LOCUS       DACAOP010000001       100259 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.001, whole genome shotgun sequence.
ACCESSION   DACAOP010000001 DACAOP010000000
VERSION     DACAOP010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 100259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100259
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.001"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(76..666)
                     /gene="paaY"
                     /locus_tag="IT892_000001"
     CDS             complement(76..666)
                     /gene="paaY"
                     /locus_tag="IT892_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
                     /protein_id="HAP3133259.1"
                     /translation="MPIYQIDGLTPVVPEESFVHPTAVLIGDVILDKGVYVGPNASLR
                     GDFGRIVVKDGANIQDNCVMHGFPEQDTVVGEDGHIGHSAILHGCIIRRNALVGMNAV
                     VMDGAVIGENSIVGASAFVKAKAEMPANYLIVGSPAKAIRELSEQELAWKKQGTHEYQ
                     VLVTRCKQTLHQVEPLREIEPGRKRLVFDENLRPKQ"
     gene            complement(648..1598)
                     /gene="paaX"
                     /locus_tag="IT892_000002"
     CDS             complement(648..1598)
                     /gene="paaX"
                     /locus_tag="IT892_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation operon negative
                     regulatory protein PaaX"
                     /protein_id="HAP3133260.1"
                     /translation="MSKLDTFIQHAVNAVPVSGTSLISSLYGDSLSHRGGEIWLGSLA
                     ALLEGLGFGERFVRTALFRLNKEGWLDVSRIGRRSFYSLSDKGLRLTRRAESKIYRAE
                     QPAWDGKWLLLLSEGLDKSTLADVKKQLIWQGFGALAPSLMASPSQKLADVQTLLHEA
                     GVADNVICFEAQIPLALSRAALRARVEECWHLTEQNAMYETFIQSFRPLVPLLKEAAD
                     ELTPERAFHIQLLLIHFYRRVVLKDPLLPEELLPAHWAGHTARQLCINIYQRVAPAAL
                     AFVSEKGETSVGELPAPGSLYFQRFGGLNIEQEALCQFIR"
     gene            complement(1699..3012)
                     /gene="paaF"
                     /locus_tag="IT892_000003"
     CDS             complement(1699..3012)
                     /gene="paaF"
                     /locus_tag="IT892_000003"
                     /EC_number="6.2.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HAP3133261.1"
                     /translation="MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKF
                     DAAGVHPDDFRELSDLRKFPCTTKQDLRDNYPFDTFAVPMEQVVRIHASSGTTGKPTV
                     VGYTQNDIDNWANIVARSLRAAGGSPKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
                     MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQLGGDASGCSLRVGVFGAEPW
                     TQAMRKEIERRLGITALDIYGLSEVMGPGVAMECLETTDGPTIWEDHFYPEIVNPHDG
                     TPLADGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRRMDRISGRSDDMLII
                     RGVNVFPSQLEEEIVKFEHLSPHYQLEVNRRGHLDSLSVKVELKESSLTLTHEQRCQV
                     CHQLRHRIKSMVGISTDVMIVNCGSIPRSEGKACRVFDLRNIVGA"
     gene            complement(3039..4244)
                     /locus_tag="IT892_000004"
     CDS             complement(3039..4244)
                     /locus_tag="IT892_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA
                     thiolase"
                     /protein_id="HAP3133262.1"
                     /translation="MREAFICDGIRTPIGRYGGALSSVRADDLAAIPLRELLVRNPRL
                     DAECIDDVILGCANQAGEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAAR
                     AIKAGDGDLLIAGGVESMSRAPFVMGKAASAFSRQAEMFDTTIGWRFVNPLMAQQFGT
                     DSMPETAENVAELLKISREDQDSFALRSQQRTAKAQSSGILAEEIVPVVLKNKKGVVT
                     EIQHDEHLRPETTLEQLRGLKAPFRANGVITAGNASGVNDGAAALIIASEQMAAAQGL
                     TPRARIVAMATAGVEPRLMGLGPVPATRRVLERAGLSIHDMDVIELNEAFAAQALGVL
                     RELGLPDDAPHVNPNGGAIALGHPLGMSGARLALAASHELHRRNGRYALCTMCIGVGQ
                     GIAMILERV"
     gene            complement(4244..4666)
                     /gene="paaI"
                     /locus_tag="IT892_000005"
     CDS             complement(4244..4666)
                     /gene="paaI"
                     /locus_tag="IT892_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyphenylacetyl-CoA thioesterase PaaI"
                     /protein_id="HAP3133263.1"
                     /translation="MSHKAWQNAHAMYENDACAKALGIDIISMDEGFAVVTMTVTAQM
                     LNGHQSCHGGQLFSLADTAFAYACNSQGLAAVASACTIDFLRPGFAGDTLTATAQVRH
                     QGKQTGVYDIEIVNQQQKTVALFRGKSHRIGGTITGEA"
     gene            complement(4656..6083)
                     /gene="paaC"
                     /locus_tag="IT892_000006"
     CDS             complement(4656..6083)
                     /gene="paaC"
                     /locus_tag="IT892_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase PaaC"
                     /protein_id="HAP3133264.1"
                     /translation="MMINVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRA
                     IDGIHARLNSRVTRGKLTAETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKAL
                     FAQLAEVCPPQTLLTTNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLA
                     TAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDA
                     ALRDGAGFPMGPLELTDLIGQDVNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGK
                     KSGLGVYDWRAEREAVVGLEAVSDSFSPMKVEKKSDGVTEIDDVLLIETQGETAQALA
                     IRLARPVVVIDKMAGKVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWR
                     TVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQH
                     HYGEERYRPCSLLRQRALLESGYES"
     gene            complement(6085..6873)
                     /gene="paaB"
                     /locus_tag="IT892_000007"
     CDS             complement(6085..6873)
                     /gene="paaB"
                     /locus_tag="IT892_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
                     isomerase"
                     /protein_id="HAP3133265.1"
                     /translation="MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVER
                     DDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPV
                     ICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA
                     MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINS
                     AETNTLDTQLDLERDYQRLAGRSADYREGVSAFLAKRSPQFTGK"
     gene            complement(6873..7640)
                     /locus_tag="IT892_000008"
     CDS             complement(6873..7640)
                     /locus_tag="IT892_000008"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dehydroadipyl-CoA hydratase"
                     /protein_id="HAP3133266.1"
                     /translation="MSELIVSRQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATD
                     TSISVCVITGNARFFAAGADLNEMAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGY
                     ALGAGCELALLCDVVVAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSG
                     ESITAQQAQQAGLVSDVFPSDLTLEYALQLASKMARHSPLALQAAKQALRQSQEVALQ
                     AGLAQERQLFTLLAATEDRHEGISAFLQKRTPDFKGR"
     gene            complement(7637..8707)
                     /gene="paaK"
                     /locus_tag="IT892_000009"
     CDS             complement(7637..8707)
                     /gene="paaK"
                     /locus_tag="IT892_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase/reductase subunit
                     PaaK"
                     /protein_id="HAP3133267.1"
                     /translation="MTTFHSLTVAKVESETRDAVTITFAVPQPLQEAYRFRPGQHLTL
                     KASFDGEELRRCYSICRSYLPGEISVAVKAIEGGRFSRYAREHIRQGMTLEVMVPQGH
                     FGYQPQAERQGRYLAIAAGSGITPMLAIIATTLQTEPESQFTLIYGNRTSQSMMFRQA
                     LADLKDKYPQRLQLLCIFSQETLDSDLLHGRIDGEKLQSLGASLINFRLYDEAFICGP
                     AAMMDDAETALKALGMPDKTIHLERFNTPGTRVKRSVNVQSDGQKVTVRQDGRDREIV
                     LNADDESILDAALRQGADLPYACKGGVCATCKCKVLRGKVAMETNYSLEPDELAAGYV
                     LSCQALPLTSDVVVDFDAKGMA"
     gene            complement(8715..9212)
                     /gene="paaD"
                     /locus_tag="IT892_000010"
     CDS             complement(8715..9212)
                     /gene="paaD"
                     /locus_tag="IT892_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415909.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate degradation protein PaaD"
                     /protein_id="HAP3133268.1"
                     /translation="MQRLATIAPPQVHEIWALLSQIPDPEIPVLTITDLGMVRNVTQM
                     GEGWVIGFTPTYSGCPATEHLIGAIREAMTTNGFTPVQVVLQLDPAWTTDWMTPDARE
                     RLREYGISPPAGHSCHAHLPPEVRCPRCASVHTTLISEFGSTACKALYRCDSCREPFD
                     YFKCI"
     gene            complement(9227..9973)
                     /gene="paaC"
                     /locus_tag="IT892_000011"
     CDS             complement(9227..9973)
                     /gene="paaC"
                     /locus_tag="IT892_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase subunit PaaC"
                     /protein_id="HAP3133269.1"
                     /translation="MNQLTAYTLRLGDNCLVLSQRLGEWCGHAPELEIDLALANIGLD
                     LLGQARNFLSYAAELAGEGDEDTLAFTRDERQFSNLLLVEQPNGNFADTIARQYFIDA
                     WHVALFTRLMESRDPQLAAISAKAIKEARYHLRFSRGWLERLGNGTDVSGQKMQQAIN
                     KLWRFTAELFDADEIDIALSEEGIAVDPRTLRAAWEAEVFAGINEATLNVPQEQAYRT
                     GGKKGLHTEHLGPMLAEMQYLQRVLPGQQW"
     gene            complement(9982..10269)
                     /gene="paaB"
                     /locus_tag="IT892_000012"
     CDS             complement(9982..10269)
                     /gene="paaB"
                     /locus_tag="IT892_000012"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit B"
                     /protein_id="HAP3133270.1"
                     /translation="MSNVYWPLYEVFVRGKQGLSHRHVGSLHAADERMALENARDAYT
                     RRSEGCSIWVVKASEIVASQPEERGEFFDPAESKVYRHPTFYTIPDGIEHM"
     gene            complement(10281..11210)
                     /gene="paaA"
                     /locus_tag="IT892_000013"
     CDS             complement(10281..11210)
                     /gene="paaA"
                     /locus_tag="IT892_000013"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit A"
                     /protein_id="HAP3133271.1"
                     /translation="MTQEERFEQRIAQETAIEPQDWMPDAYRKTLIRQIGQHAHSEIV
                     GMLPEGNWITRAPTLRRKAILLAKVQDEAGHGLYLYSAAETLGCAREDIYQKMLDGRM
                     KYSSIFNYPTLSWADIGVIGWLVDGAAIVNQVALCRTSYGPYARAMVKICKEESFHQR
                     QGFEACMALAQGSEAQKQMLQDAINRFWWPALMMFGPNDDNSPNSARSLTWKIKRFTN
                     DELRQRFVDNTVPQVEMLGMTVPDPDLHFDTESGHYRFGEIDWQEFNEVINGRGICNQ
                     ERLDAKRKAWEEGTWVREAALAHAQKQHARKVA"
     gene            11495..13540
                     /gene="paaZ"
                     /locus_tag="IT892_000014"
     CDS             11495..13540
                     /gene="paaZ"
                     /locus_tag="IT892_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation bifunctional
                     protein PaaZ"
                     /protein_id="HAP3133272.1"
                     /translation="MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAA
                     RQFAIEKGAPALRAMTFIERAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEG
                     GIGTLFTYASLGSRELPDDTLWPEDELIPLSKEGGFAARHLLTSKSGVAVHINAFNFP
                     CWGMLEKLAPTWLGGMPAIIKPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDL
                     LDHLDSQDVVTFTGSAATGQMLRVQPNIVAKSIPFTMEADSLNCCVLGEDVTPDQPEF
                     ALFIREVVREMTTKAGQKCTAIRRIIVPQALVNAVSDALVARLQKVVVGDPAQEGVKM
                     GALVNAEQRADVQEKVNILLAAGCEIRLGGQADLSAAGAFFPPTLLYCPQPDETPAVH
                     ATEAFGPVATLMPAQNQRHALQLACAGGGSLAGTLVTADPQIARQFIADAARTHGRIQ
                     ILNEESAKESTGHGSPLPQLVHGGPGRAGGGEELGGLRAVKHYMQRTAVQGSPTMLAA
                     ISKQWVRGAKVEEDRIHPFRKYFEELQPGDSLLTPRRTMTEADIVNFACLSGDRFYAH
                     MDKIAAAESIFGERVVHGYFVLSAAAGLFVDAGVGPVIANYGLESLRFIEPVKPGDTI
                     QVRLTCKRKTLKKQRSAEEKPTGVVEWAVEVFNQHQTPVALYSILTLVARQHGDFVD"
     gene            13788..16061
                     /gene="tynA"
                     /locus_tag="IT892_000015"
     CDS             13788..16061
                     /gene="tynA"
                     /locus_tag="IT892_000015"
                     /EC_number="1.4.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415904.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primary-amine oxidase"
                     /protein_id="HAP3133273.1"
                     /translation="MGSPSLYSARKTTLALAVALSFAWQAPVFAHGGEAHMVPMDKTL
                     KEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVPVVMKDNKAWVSD
                     TFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPNTRFTEISLLP
                     PDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVL
                     LDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVI
                     SYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVK
                     PMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSL
                     GGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP
                     MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENG
                     TIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDV
                     DGENNSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKE
                     NRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEG
                     KYPNRSTHDTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKP
                     WNFFDETPTLGALKKDK"
     gene            complement(16119..17618)
                     /locus_tag="IT892_000016"
     CDS             complement(16119..17618)
                     /locus_tag="IT892_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415903.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HAP3133274.1"
                     /translation="MTEPHVAVLSQVQQFLDRQHGLYIDGRPGPAQSEKRLAIFDPAT
                     GQEIASTADANEADVDNAVMSAWRAFVSRRWAGRLPAERERILLRFADLVEQHSEELA
                     QLETLEQGKSIAISRAFEVGCTLNWMRYTAGLTTKIVGKTLDLSIPLPQGARYQAWTR
                     KEPVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSETTPLTMLRVAELASEAGI
                     PDGVFNVVTGSGAVCGAALTSHPHGAKISFTGSTATGKGIARTAADHLTRVTLELGGK
                     NPAIVLKDADPQWVIEGLMTGSFLNQGQVCAASSRIYIEAPLFDTLVSGFEQAVKSLQ
                     VGPGMSPVAQINPLVSRAHCDKVCSFLDDAQAQQAELIRGSNGPAGEGYYVAPTLVVN
                     PDAKLRLTREEVFGPVVNLVRVADGEEALQLANDTEYGLTASVWTQNLSQALEYSDRL
                     QAGTVWVNSHTLIDANLPFGGMKQSGTGRDFGPDWLDGWCETKSVCVRY"
     gene            17854..18759
                     /gene="feaR"
                     /locus_tag="IT892_000017"
     CDS             17854..18759
                     /gene="feaR"
                     /locus_tag="IT892_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator FeaR"
                     /protein_id="HAP3133275.1"
                     /translation="MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLDTHFAKGL
                     KLSTVTTSGVNLSRTWQEVKGSDDAWFYTVFQLSGQAIMEQDERQVQIGAGDITLLDA
                     SRPCSLYWQESSKQISLLLPRTLLEQYFPHQKPVCAERLDADLPMVQLSHRLLQESMN
                     NPALSETESEAALQAMVCLLRPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEW
                     IAGETGMSVRSLYRMFADKGLVVAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFS
                     DQSHFSTVFKQRFGMTPGEYRRKFR"
     gene            complement(18931..19257)
                     /locus_tag="IT892_000018"
     CDS             complement(18931..19257)
                     /locus_tag="IT892_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbL family protein"
                     /protein_id="HAP3133276.1"
                     /translation="MKKTLLLCAFLVGLVSSNVMALTLDEARTQGRVGETFYGYLVAL
                     KTDAETEKLVADINAERKASYQQLAKQNNVSVDDIAKLAGQKLVARAKPGEYVQGING
                     KWVRKF"
     gene            complement(19265..19450)
                     /locus_tag="IT892_000019"
     CDS             complement(19265..19450)
                     /locus_tag="IT892_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnbE family lipoprotein"
                     /protein_id="HAP3133277.1"
                     /translation="MKILLAALTSSFMLVGCTPRIEVAAPKEPITINMNVKIEHEIII
                     KADKDVEELLETRSDLF"
     gene            complement(19447..22086)
                     /locus_tag="IT892_000020"
     CDS             complement(19447..22086)
                     /locus_tag="IT892_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbH family protein"
                     /protein_id="HAP3133278.1"
                     /translation="MLGKYKAVLALLLLIILVPLTLLMTLGLWVPTLAGIWLPLGTRI
                     ALDESPRITRKGLIIPDLRYLVGDCQLAHITNASLSHPSRWLLNVGTVELDSACLAKL
                     PQTEQSPAAPKTLAQWQAMLPNTWINIDKLIFSPWQEWQGKLSLALTSDIQQLRYQGE
                     KVKFQGQLKGQQLTVSELDVVAFENQPPVKLVGEFAMPLVPDGLPVSGHATATLNLPQ
                     EPSLVDAELDWQENSGQLIVLARDNGDPLLDLPWQITRQQLTVSDGRWSWPYAGFPLS
                     GRLGVKVDNWQAGLENALVSGRLSVLTQGQAGKGNAVLNFGPGKLSMDNSQLPLQLTG
                     EAKQADLILYARLPAQLSGSLSDPTLTFEPGALLRSKGRVIDSLDIDEIRWPLAGVKV
                     TQRGVDGRLQAILQAHENELGDFVLHMDGLANDFLPDAGRWQWRYWGKGSFTPMNATW
                     DVAGKGEWHDSTITLTDLSTGFDQLQYGTMTVEKPRLILDKPIVWVRDAQHPSFSGAL
                     SLDAGQTLFTGGSVLPPSTLKFSVDGRDPTYFLFKGDLHAGEIGPVRVNGRWDGIRLR
                     GNAWWPKQSLTVFQPLVPPDWKMNLRDGELYAQVAFSAAPEQGFRAGGHGVLKGGSAW
                     MPDNQVNGVDFVLPFRFADGAWHLGTRGPVTLRIAEVINLVTAKNITADLQGRYPWTE
                     EEPLLLTDVSVDVLGGNVLMKQLRMPQHDPALLRLNNLSSSELVSAVNPKQFAMSGAF
                     SGALPLWLNNEKWIVKDGWLANSGPMTLRLDKDTADAVVKDNMTAGSAINWLRYMEIS
                     RSSTKINLDNLGLLTMQANITGTSRVDGKSGTVNLNYHHEENIFTLWRSLRFGDNLQA
                     WLEQNARLPGNDCPQGKECEEKQ"
     gene            22294..23283
                     /gene="ldhA"
                     /locus_tag="IT892_000021"
     CDS             22294..23283
                     /gene="ldhA"
                     /locus_tag="IT892_000021"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HAP3133279.1"
                     /translation="MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANG
                     CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDP
                     EAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAML
                     RILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEA
                     AFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVI
                     QDDVFRRLSACHNVLFTGHQAFLTAEALTSISQTTLQNLSNLEKGETCPNELV"
     gene            23394..23816
                     /gene="hslJ"
                     /locus_tag="IT892_000022"
     CDS             23394..23816
                     /gene="hslJ"
                     /locus_tag="IT892_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HslJ"
                     /protein_id="HAP3133280.1"
                     /translation="MKKVAAFVALSLLMAGCVSNDKIAVTPEQLQHHRFVLESVNGKP
                     VTSDKNPPEISFGEKMMISGSMCNRFSGEGKLSNGELTAKGLAMTRMMCANPQLNELD
                     NTISEMLKEGAQVDLTANQLTLATAKQTLTYKLADLMN"
     gene            complement(23813..24079)
                     /locus_tag="IT892_000023"
     CDS             complement(23813..24079)
                     /locus_tag="IT892_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HAP3133281.1"
                     /translation="MRAAFWVGCAALLLSACSSEPVQQATAAHVAPGLKASMSSSGEA
                     NCAMIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY"
     gene            24353..27877
                     /gene="nifJ"
                     /locus_tag="IT892_000024"
     CDS             24353..27877
                     /gene="nifJ"
                     /locus_tag="IT892_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAP3133282.1"
                     /translation="MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGL
                     KNVWGDTPRVVEMQSEAGAIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTP
                     FVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISQIATLKSR
                     VPFIHFFDGFRTSHEINKIIPLADDTILDLMPQVEIDAHRARALNPEHPVIRGTSANP
                     DTYFQSREATNPWYNAVYDHVEQAMNDFSAATGRQYQPFEYYGHPQAERVIILMGSAI
                     GTCEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGSVRSVAVLDRTKEPGAQAE
                     PLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCVLAVFAELNAAKPKARF
                     TVGIYDDVTNLSLPLPENTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQ
                     GYFVYDSKKAGGLTVSHLRVSEQPIRSAYLISQADFVGCHQLQFIDKYQMAERLKPGG
                     IFLLNTPYSADEVWSRLPQEVQAVLNQKKARFYVINAAKIARECGLAARINTVMQMAF
                     FHLTQILPGDSALAELQGAIAKSYSSKGQDLVERNWQALALARESVEEVPLQPVNPHS
                     ANRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIP
                     IWKEELCTQCNHCVAACPHSAIRAKVVPPEAMENAPASLHSLDVKSRDMRGQKYVLQV
                     APEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKINYDFFLNLPEIDRSKL
                     ERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLP
                     STPYTTDANGRGPAWANSLFEDNAEFGLGFRLTVDQHRVRVLRLLDQFADKIPAELLT
                     ALKSDATPEVRREQVAALRQQLNDVAEAHELLRDADALVEKSIWLIGGDGWAYDIGFG
                     GLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMM
                     MYGHVYVAQISLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQL
                     TATGFWPLYRFDPRRADEGKLPLALDSRPPSEALEETLLHEQRFRRLNSQQPEVAEQL
                     WKDAAADLQKRYDFLAQMAGKAEKSNTD"
     gene            28244..29377
                     /gene="ompN"
                     /locus_tag="IT892_000025"
     CDS             28244..29377
                     /gene="ompN"
                     /locus_tag="IT892_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpN"
                     /protein_id="HAP3133283.1"
                     /translation="MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNSAKDGDQSYARLGFKGETQINDQLTGYGQWEYNIQANNTESSKNQSWTRLAFAGL
                     KFADYGSFDYGRNYGVMYDIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFF
                     GLVNGLNFAVQYQGNNEGASNGQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAY
                     TSSDRTNDQVNHTAAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDSDYAVAN
                     KTQNFEVTAQYQFDFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADIGATY
                     YFNKNMSTYVDYKINLLDEDDSFYAANGISTDDIVALGLVYQF"
     gene            29518..29952
                     /gene="uspF"
                     /locus_tag="IT892_000026"
     CDS             29518..29952
                     /gene="uspF"
                     /locus_tag="IT892_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415894.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspF"
                     /protein_id="HAP3133284.1"
                     /translation="MNRTILVPIDISDSELTQRVISHVEEEAKIDDAEVHFLTVIPSL
                     PYYASLGLAYSAELPAMDDLKAEAKSQLEEIIKKFKLPTDRVHVHVEEGSPKDRILEL
                     AKKIPAHMIIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR"
     gene            30129..31064
                     /gene="ttcA"
                     /locus_tag="IT892_000027"
     CDS             30129..31064
                     /gene="ttcA"
                     /locus_tag="IT892_000027"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HAP3133285.1"
                     /translation="MSQNQEISKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMV
                     CLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKI
                     VEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
                     NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPN
                     LQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGD
                     LAFDREEIPLQPACWQPEEDENQLDELRLNVVEVK"
     gene            complement(31193..32566)
                     /gene="dbpA"
                     /locus_tag="IT892_000028"
     CDS             complement(31193..32566)
                     /gene="dbpA"
                     /locus_tag="IT892_000028"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
                     /protein_id="HAP3133286.1"
                     /translation="MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVR
                     VQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTK
                     ILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
                     MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQ
                     QFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLE
                     QRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWDPEVHVHRIGRTAR
                     AGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKK
                     AKMRPGDVLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKT
                     CRVRLLK"
     gene            complement(33044..34027)
                     /gene="zntB"
                     /locus_tag="IT892_000029"
     CDS             complement(33044..34027)
                     /gene="zntB"
                     /locus_tag="IT892_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZntB"
                     /protein_id="HAP3133287.1"
                     /translation="MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLH
                     LNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPD
                     QLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSE
                     FIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPW
                     MSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMV
                     FLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHRSKWL"
     gene            34282..35514
                     /gene="dgcM"
                     /locus_tag="IT892_000030"
     CDS             34282..35514
                     /gene="dgcM"
                     /locus_tag="IT892_000030"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415857.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcM"
                     /protein_id="HAP3133288.1"
                     /translation="MITHNFNTLDLLTSPVWIVSPFEEQLIYANSAAKLLMQDLTFSQ
                     LRTGPYSVSSQKELPKYLSDLQNQHDIIEILTVQRKEEETALSCRLVLRKLTETEPVI
                     IFEGIEAPATLGLKASRSANYQRKKQGFYARFFLTNSAPMLLIDPSRDGQIVDANLAA
                     LNFYGYNHETMCQKHTWEINMLGRRVMPIMHEISHLPGGHKPLNFVHKLADGSTRHVQ
                     TYAGPIEIYGDKLMLCIVHDITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQM
                     QHLAIAQDYSLLLIDTDRFKHINDLYGHSKGDEVLCALARTLESCARKGDLVFRWGGE
                     EFVLLLPRTPLDTALSLAETIRVSVAKVSISGLPRFTVSIGVAHHEGNESIDELFKRV
                     DDALYRAKNDGRNRVLAA"
     gene            complement(35535..36098)
                     /gene="smrA"
                     /locus_tag="IT892_000031"
     CDS             complement(35535..36098)
                     /gene="smrA"
                     /locus_tag="IT892_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA endonuclease SmrA"
                     /protein_id="HAP3133289.1"
                     /translation="MNLDDKSLFLDAMEDVQPLKRATDVHWHPTRNQRAPQRIDTLQL
                     DNFLTTGFLDIIPLSQPLEFRREGLQHGVLDKLRSGKYPQQASLNLLRQPVEECRKMV
                     FSFIQQALADGLRNVLIIHGKGRDDKSHANIVRSYVARWLTEFDDVQAYCTALPHHGG
                     SGACYVALRKTAQAKQENWERHAKRSR"
     gene            complement(36428..37336)
                     /locus_tag="IT892_000032"
     CDS             complement(36428..37336)
                     /locus_tag="IT892_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3133290.1"
                     /translation="MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELE
                     EGLAAQLFFRRSKGVTLTDAGESFYQHASLILEELRAAQEDIRQRQGQLAGQINIGMG
                     ASISRSLMPAVISRFHQQHPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHE
                     FTFEKLLEKQFAIFCRPGHPAIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQT
                     PQVGVVCETFSACISLVAKSDFLSILPEEMGCDPLHGQGLVMLPVSEILPKAAYYLIQ
                     RRDSRQTPLTASLITQFRRECGYLQS"
     gene            37512..38822
                     /locus_tag="IT892_000033"
     CDS             37512..38822
                     /locus_tag="IT892_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit A"
                     /protein_id="HAP3133291.1"
                     /translation="MESLNQFVNSLAPKLSHWRRDFHHYAESGWVEFRTATLVAEELH
                     QLGYSLALGREVVNESSRMGLPDEFTLQREFERARQQGALAQWIAAFEGGFTGIVATL
                     DTGRPGPVMAFRVDMDALDLSEEQDVSHRPYRDGFASCNAGMMHACGHDGHTAIGLGL
                     AHTLKQFESGLHGVIKLIFQPAEEGTRGARAMVDAGVVDDVDYFTAVHIGTGVPAGTV
                     VCGSDNFMATTKFDAHFTGTAAHAGAKPEDGHNALLAAAQATLALHAIAPHSEGASRV
                     NVGVMQAGSGRNVVPASALLKVETRGASDVINQYVFDRAQQAIQGAATMYGVGVETRL
                     MGAATASSPSPQWVAWLQSQAAQVAGVNQAIERVEAPAGSEDATLMMARVQQHQGQAS
                     YVVFGTQLAAGHHNEKFDFDEQVLAIAVETLARTALNFPWTRGI"
     gene            38822..40267
                     /locus_tag="IT892_000034"
     CDS             38822..40267
                     /locus_tag="IT892_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit B"
                     /protein_id="HAP3133292.1"
                     /translation="MQEIYRFIDDAIEADRQRYTDIADQIWDHPETRFEEFWSAEHLA
                     SALESAGFTVTRNVGNIPNAFIASFGQGKPVIALLGEYDALAGLSQQAGCAQPTSVTP
                     GENGHGCGHNLLGTAAFAAAIAVKKWLEQYGQGGTVRFYGCPGEEGGSGKTFMVREGV
                     FDDVDAALTWHPEAFAGMFNTRTLANIQASWRFKGIAAHAANSPHLGRSALDAVTLMT
                     TGTNFLNEHIIEKARVHYAITNSGGISPNVVQAQAEVLYLIRAPEMTDVQHIYDRVAK
                     IAEGAALMTETTVECRFDKACSSYLPNRTLENAMYQALSHFGTPEWNSEELAFAKQIQ
                     ATLTSNDRQNSLNNIAATGGENGKVFALRHRETVLANEVAPYAATDNVLAASTDVGDV
                     SWKLPVAQCFSPCFAVGTPLHTWQLVSQGRTSIAHKGMLLAAKTMAATTVNLFLDSGL
                     LQECQQEHQQVTDTQPYHCPIPKNVTPSPLK"
     gene            40304..41830
                     /gene="abgT"
                     /locus_tag="IT892_000035"
     CDS             40304..41830
                     /gene="abgT"
                     /locus_tag="IT892_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415852.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate transporter"
                     /protein_id="HAP3133293.1"
                     /translation="MSMSSIPSSSQSGKLYGWVERIGNKVPHPFLLFIYLIIVLMVTT
                     AILSAFGVSAKNPTDGTPVVVKNLLSVEGLHWFLPNVIKNFSGFAPLGAILALVLGAG
                     LAERVGLLPALMVKMASHVNARYASYMVLFIAFFSHISSDAALVIMPPMGALIFLAVG
                     RHPVAGLLAAIAGVGCGFTANLLIVTTDVLLSGISTEAAAAFNPQMHVSVIDNWYFMA
                     SSVVVLTIVGGLITDKIIEPRLGQWQGNSDEKLQTLTESQRFGLRIAGVVSLLFIAAI
                     ALMVIPQNGILRDPINHTVMPSPFIKGIVPLIILFFFVVSLAYGIATRTIRRQADLPH
                     LMIEPMKEMAGFIVMVFPLAQFVAMFNWSNMGKFIAVGLTDILESSGLSGIPAFVGLA
                     LLSSFLCMFIASGSAIWSILAPIFVPMFMLLGFHPAFAQILFRIADSSVLPLAPVSPF
                     VPLFLGFLQRYKPDAKLGTYYSLVLPYPLIFLVVWLLMLLAWYLVGLPIGPGIYPRLS
                     "
     gene            41841..42356
                     /gene="ogt"
                     /locus_tag="IT892_000036"
     CDS             41841..42356
                     /gene="ogt"
                     /locus_tag="IT892_000036"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAP3133294.1"
                     /translation="MLRLLEEKIATPLGPLWVICDEQFRLRAVEWEEYSERMVQLLDI
                     HYRKEGYERISATNPGGLSDKLREYFAGNLSIIDTLPTATGGTPFQREVWKTLRTIPC
                     GQVMHYGQLAEQLGRPGAARAVGAANGSNPISIVVPCHRVIGRNGTMTGYAGGVQRKE
                     WLLRHEGYLLL"
     gene            42551..43303
                     /locus_tag="IT892_000037"
     CDS             42551..43303
                     /locus_tag="IT892_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007849744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FNR family transcription factor"
                     /protein_id="HAP3133295.1"
                     /translation="MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDN
                     IIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFD
                     AIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
                     LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRF
                     QKSGMLAVKGKYITIENNDALAQLAGHTRNVA"
     gene            43455..44405
                     /gene="uspE"
                     /locus_tag="IT892_000038"
     CDS             43455..44405
                     /gene="uspE"
                     /locus_tag="IT892_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspE"
                     /protein_id="HAP3133296.1"
                     /translation="MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDF
                     SYEMTTLLSSDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQ
                     EVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
                     NLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYN
                     DAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGI
                     SAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD"
     gene            complement(44455..44712)
                     /locus_tag="IT892_000039"
     CDS             complement(44455..44712)
                     /locus_tag="IT892_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2534 family protein"
                     /protein_id="HAP3133297.1"
                     /translation="MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIP
                     LSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFLGGEEQ"
     gene            44956..45987
                     /gene="ynaI"
                     /locus_tag="IT892_000040"
     CDS             44956..45987
                     /gene="ynaI"
                     /locus_tag="IT892_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low conductance mechanosensitive channel YnaI"
                     /protein_id="HAP3133298.1"
                     /translation="MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHA
                     VQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDFICTSLIAVILTIKLFLLINQFE
                     KQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAG
                     KDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKITTFDNRPLYVPN
                     SLFSSISVENPGRMTNRRITTTIGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLV
                     YFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSHGADFAFPSQTLYMD
                     NITPPEQGR"
     gene            complement(46038..47651)
                     /locus_tag="IT892_000041"
     CDS             complement(46038..47651)
                     /locus_tag="IT892_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3133299.1"
                     /translation="MKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDE
                     PASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDNA
                     KWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTA
                     VDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKERV
                     VNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKL
                     LKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTIDRRLMTEKVLGTGEKPA
                     WHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQ
                     KIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLL
                     TSTHSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAEKILMEQAPIAPIYQYTNG
                     RLIKPWLKGYPINNPEDVAYSRTMYIVKH"
     gene            complement(47988..48887)
                     /locus_tag="IT892_000042"
     CDS             complement(47988..48887)
                     /locus_tag="IT892_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3133300.1"
                     /translation="MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEE
                     RLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDSAMASLSDLQNRPSGTIRITTVE
                     HAAKTILLPAMRTFLKSHPEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
                     GPDIPMAIVGSPDYFSRRSVPTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVR
                     MEGQLLLNTIDLIIDAAIDGHGLAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYY
                     PHRRHAGSAFSLFIDRLKYKGAV"
     gene            49025..49945
                     /locus_tag="IT892_000043"
     CDS             49025..49945
                     /locus_tag="IT892_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415843.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP3133301.1"
                     /translation="MMNNKVSFTNSNNPTISLSAVIYFPPKFDETRQYQAIVLSHPGG
                     GVKEQTAGTYAKKLAEKGFVTIAYDASYQGESGGEPRQLENPYIRTEDISAVIDYLTT
                     LSYVDNTRIGAMGICAGAGYTANAAIQDRRIKAIGTVSAVNIGSIFRNGWENNVKSID
                     ALPYVEAGSNARTSDISSGEYAIMPLAPMKESDAPNEELRQAWEYYHTPRAQYPTAPG
                     YATLRSLNQIITYDAYHMAEVYLTQPTQIVAGSQAGSKWMSDDLYDRASSQDKRYHIV
                     EGANHMDLYDGKAYVAEAISVLAPFFEETL"
     gene            49945..50010
                     /locus_tag="IT892_000044"
     CDS             49945..50010
                     /locus_tag="IT892_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133302.1"
                     /translation="MKHIQIRNSDMDWHIAANNLG"
     gene            50016..50153
                     /locus_tag="IT892_000045"
                     /pseudo
     CDS             50016..50153
                     /locus_tag="IT892_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707232.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dehydratase"
     gene            50280..51008
                     /gene="mpaA"
                     /locus_tag="IT892_000046"
     CDS             50280..51008
                     /gene="mpaA"
                     /locus_tag="IT892_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415842.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide amidase MpaA"
                     /protein_id="HAP3133303.1"
                     /translation="MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLI
                     LAGTHGDENSSVVTLSCALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFP
                     AANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPL
                     ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCEDLNLHCITAEFPPISSDE
                     ASEKYLFAMANLLRWHPKDAIRPS"
     gene            complement(50983..51948)
                     /gene="ycjG"
                     /locus_tag="IT892_000047"
     CDS             complement(50983..51948)
                     /gene="ycjG"
                     /locus_tag="IT892_000047"
                     /EC_number="5.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415841.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-Ala-D/L-Glu epimerase"
                     /protein_id="HAP3133304.1"
                     /translation="MRTVKVFEEAWPLHTPFVIARGSRSEARVVVVELEEEGIKGTGE
                     CTPYPRYGESDASVMAQIMSVVPQLEKGLTREELQKILPAGAARNALDCALWDLAARR
                     QQQSLADLIGITLPETVITAQTVVIGTPDQMANSASTLWQAGAKLLKVKLDNHLISER
                     MVAIRTAVPDATLIVDANESWRAEGLAARCQLLADLGVAMLEQPLPAQDDAALENFIH
                     PLPICADESCHTRSNLKALKGRYEMVNIKLDKTGGLTEALALATEARAQGFSLMLGCM
                     LCTSRAISAALPLVPQVSFADLDGPTWLAVDVEPALQFTTGELHL"
     gene            52067..52573
                     /gene="tpx"
                     /locus_tag="IT892_000048"
     CDS             52067..52573
                     /gene="tpx"
                     /locus_tag="IT892_000048"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HAP3133305.1"
                     /translation="MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFA
                     GKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNN
                     VITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYE
                     AALAVLKA"
     gene            complement(52617..54158)
                     /gene="tyrR"
                     /locus_tag="IT892_000049"
     CDS             complement(52617..54158)
                     /gene="tyrR"
                     /locus_tag="IT892_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TyrR"
                     /protein_id="HAP3133306.1"
                     /translation="MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFA
                     ELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKV
                     DMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLME
                     ITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVE
                     QAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRAGKPYLALNCASIPEDAVESELF
                     GHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVR
                     VICATQKNLVELVQKGMFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQ
                     GVPRPKLAADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATV
                     AVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQ
                     KKNEE"
     gene            complement(54306..55367)
                     /locus_tag="IT892_000050"
     CDS             complement(54306..55367)
                     /locus_tag="IT892_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01620 family protein"
                     /protein_id="HAP3133307.1"
                     /translation="MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDE
                     AQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVAL
                     GGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQ
                     QAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMI
                     AVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVR
                     EVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRR
                     QLIGQVKETLQKGKTPSEK"
     gene            complement(55364..56761)
                     /locus_tag="IT892_000051"
     CDS             complement(55364..56761)
                     /locus_tag="IT892_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjX family protein"
                     /protein_id="HAP3133308.1"
                     /translation="MKRLKNELNALVNRGVDRHLRLAVTGLSRSGKTAFITAMVNQLL
                     NIHAGARLPLLSAVREERLLGVKRIPQRDFGIPRFTYDEGLAQLYGDPPAWPTPTRGV
                     SEIRLALRFKSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMTGLL
                     NGQRGEWSAKWRMMSEGLDPLAPADENRLADIAAAWTDYLHHCKEQGLHFIQPGRFVL
                     PGDMAGAPALQFFPWPDVDTWGESKLAQADKHTNAGMLRERFNYYCEKVVKGFYKNHF
                     LRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTLFRRLFSPVIDKLLF
                     AATKADHVTIDQHANMVSLLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGIIDVNG
                     EKIPALRGNRLSDGAPLTVYPGEVPARLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHI
                     RLDAALEFLIGDKLR"
     gene            56917..57915
                     /locus_tag="IT892_000052"
     CDS             56917..57915
                     /locus_tag="IT892_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP3133309.1"
                     /translation="MSPTIYDIARVAGVSKSTVSRVLNKQTNISPEAREKVLRAIEEL
                     QYQPNKLARALTSSGFDAIMVISTRSTKTTAGNPFFSEVLHAITAKAEEEGFDVILQT
                     SHNPAEDLQKCESKIKQKMIKGIIMLSSPADESFFAQLDKYDIPVVVIGKVEGQYAHV
                     YSVDTDNFGDSIALTDALIESGHQNIACLHAPLDVHVSVDRVNGYKQSLAAHNIAVRD
                     EWIVDGGYTHETALKAARQLLSQSPLPEAVFATDSLKLMSIYRAAAEKNIAIPQQLAV
                     VGYSNETLSFILTPAPGGIDVPTQELGQQSCELLFRLISGKPSPQNITVATHMTLK"
     gene            complement(58026..58931)
                     /gene="ompG"
                     /locus_tag="IT892_000053"
     CDS             complement(58026..58931)
                     /gene="ompG"
                     /locus_tag="IT892_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monomeric porin OmpG"
                     /protein_id="HAP3133310.1"
                     /translation="MKKLLPCTALVMCAGMACAQAEERNDWHFNIGAMYEIENVEGYG
                     EDMDGLAEPSVYFNAANGPWRIALAYYQEGPVDYSAGKRGTWFDRPELEVHYQFLEND
                     DFSFGLTGGFRNYGYHYVDEPGKDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFAN
                     DLNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYL
                     PLTLGNHSVTPYTRIGLDRWSNWDWQDDIEREGHDFNRVGLFYGYDFQNGLSVSLEYA
                     FEWQDHDEGDSDKFHYAGVGVNYSF"
     gene            complement(58976..60058)
                     /locus_tag="IT892_000054"
     CDS             complement(58976..60058)
                     /locus_tag="IT892_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP3133311.1"
                     /translation="MAQLSLQHIQKIYDNQVHVVKDFNLEIADKEFIVFVGPSGCGKS
                     TTLRMIAGLEEISGGDLLIDGKRMNDVPAKARNIAMVFQNYALYPHMTVYDNMAFGLK
                     MQKIAKEVIDERVNWAAQILGLREYLKRKPGALSGGQRQRVALGRAIVREAGVFLMDE
                     PLSNLDAKLRVQMRAEISKLHQKLNTTMIYVTHDQTEAMTMATRIVIMKDGIVQQVGA
                     PKTVYNQPANMFVSGFIGSPAMNFIRGTIDGDKFVTETLKLTIPEEKLAVLKTQESLH
                     KPIVMGIRPEDIHPDAQEENNISAKISVAELTGAEFMLYTTVGGHELVVRAGALNDYH
                     AGENITIHFDMTKCHFFDAETEIAIR"
     gene            complement(60072..60731)
                     /gene="pgmB"
                     /locus_tag="IT892_000055"
     CDS             complement(60072..60731)
                     /gene="pgmB"
                     /locus_tag="IT892_000055"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP3133312.1"
                     /translation="MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESL
                     KGISRDESLRRILQHGGKEGDFNSQERAQLAYRKNLLYVHSLRELTVNAVLPGIRSLL
                     ADLRAQQISVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
                     GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTESLTWPRLSAFWQN
                     V"
     gene            complement(60728..62995)
                     /gene="ycjT"
                     /locus_tag="IT892_000056"
     CDS             complement(60728..62995)
                     /gene="ycjT"
                     /locus_tag="IT892_000056"
                     /EC_number="2.4.1.230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kojibiose phosphorylase"
                     /protein_id="HAP3133313.1"
                     /translation="MTRPVTLSEPHFSQHTLNKYASLMAQGNGYLGLRASHEEDYTRQ
                     TRGMYLAGLYHRAGKGEINELVNLPDVVGMEIAINGEVFSLSHEAWQRELDFASGELR
                     RNVVWRTSNGSGYTIASRRFVSADQLPLIALEITITPLDADASVLISTGIDATQTNHG
                     RQHLDETQVRVFGQHLMQGSYTTQDGRSDVAISCCCKVSGDVQQCYTAKERRLLQHTS
                     AQLHAGETMTLQKLVWIDWRDDRQAALDEWGSASLRQLEMCAQQSYDQLLAASTENWR
                     QWWQKRRITVNGGEAHDQQALDYALYHLRIMTPAHDERSSIAAKGLTGEGYKGHVFWD
                     TEVFLLPFHLFSDPTVARSLLRYRWHNLPGAQEKARRNGWQGALFPWESARSGEEETP
                     EFAAINIRTGLRQKVASAQAEHHLVADIAWAVIQYWQTTGDESFIAHEGMALLLETAK
                     FWISRAVRVNDRLEIHDVIGPDEYTEHVNNNAYTSYMARYNVQQALNIARQFGCSDDA
                     FIHRAEMFLKELWMPEIQPDGVLPQDDSFMAKPAINLAKYKAAAGKQTILLDYSRAEV
                     NEMQILKQADVVMLNYMLPEQFSAASCLANLQFYEPRTIHDSSLSKAIHGIVAARCGL
                     LTQSYQFWREGTEIDLGADPHSCDDGIHAAATGAIWLGAIQGFAGVSVRDGELHLNPA
                     LPEQWQQLSFPLFWQGCELQVTLDAQRIAIRTSAPVSLRLNGQLITVAEESVFCLGDF
                     ILPFNGTATKHQEDE"
     gene            complement(62992..64047)
                     /locus_tag="IT892_000057"
     CDS             complement(62992..64047)
                     /locus_tag="IT892_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP3133314.1"
                     /translation="MKSAMTSSPLRVAIIGAGQVADKVHASYYCTRNDLELVAVCDSR
                     LSQAQALAEKYGNASVWDDPQAMLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCE
                     KPPAMTPEQAREMCDTARKLGKVLAYDFHHRFALDTQQLREQVTNGVLGEIYVTTARA
                     LRRCGVPGWGVFTNKELQGGGPLIDIGIHMLDAAMYVLGFPAVKSVNAHSFQKIGTQK
                     SCGQFGEWDPATYSVEDSLFGTIEFHNGGILWLETSFALNIREQSIMNVSFCGDKAGA
                     TLFPAHIYTDNNGELMTLMQREMADDNRHLRSMEAFINHVQGKPVMIADAEQGYIIQQ
                     LVAALYQSAETGTRVEL"
     gene            complement(64057..64845)
                     /locus_tag="IT892_000058"
     CDS             complement(64057..64845)
                     /locus_tag="IT892_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP3133315.1"
                     /translation="MKIGTQNQAFFPENILEKFRYIKEMGFDGFEIDGKLLVNNIEEV
                     KAAIKETGLPVTTACGGYDGWIGDFIEERRLNGLKQIERILEALAEVGGKGIVVPAAW
                     GMFTFRLPPMTSPRSLDGDRKMVSDSLRVLEQVAARTGTVVYLEPLNRYQDHMINTLA
                     DARRYIVENDLKHVQIIGDFYHMNIEEDNLAQALHDNRDLLGHVHIADNHRYQPGSGT
                     LDFHALFEQLRADNYQGYVVYEGRIRAEDPAQAYRDSLAWLRTC"
     gene            complement(64864..65916)
                     /locus_tag="IT892_000059"
     CDS             complement(64864..65916)
                     /locus_tag="IT892_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAP3133316.1"
                     /translation="MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVD
                     FRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVG
                     DSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
                     VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEI
                     KTLTGKQGADVIIETSGYADALQSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNN
                     AKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLIDPVVTFANSPESYMQ
                     YVDQHPEQSIKMGVTF"
     gene            complement(65947..66789)
                     /locus_tag="IT892_000060"
     CDS             complement(65947..66789)
                     /locus_tag="IT892_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP3133317.1"
                     /translation="MATNKRTLSRIGFYCGLALFLIITLFPFFVMLMTSFKGAKEAIS
                     LHPTLLPQQWTLEHYVDIFNPMIFPFVDYFRNSLVVSVVSSVVAVFLGILGAYALSRL
                     RFKGRMTINASFYTVYMFSGILLVVPLFKIITALGIYDTEMALIITMVTQTLPTAVFM
                     LKSYFDTIPDEIEEAAMMDGLNRLQIIFRITVPLAMSGLISVFVYCFMVAWNDYLFAS
                     IFLSSASNFTLPVGLNALFSTPDYIWGRMMAASLVTALPVVIMYALSERFIKSGLTAG
                     GVKG"
     gene            complement(66776..67657)
                     /locus_tag="IT892_000061"
     CDS             complement(66776..67657)
                     /locus_tag="IT892_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP3133318.1"
                     /translation="MNRLFSGRSDMPFALLLLAPSLLLLGGLVAWPMVSNIEISFLRL
                     PLNPNIESTFVGVSNYVRILSDPGFWHSLWMTVWYTALVVAGSTVLGLAVAMFFNREF
                     RLRKTARSLVILSYVTPSISLVFAWKYMFNNGYGIVNYLGVDLLHLYEQAPLWFDNPG
                     SSFVLVVLFAIWRYFPYAFISFLAILQTIDKSLYEAAEMDGANAWQRFRIVTLPAIMP
                     VLATVVTLRTIWMFYMFADVYLLTTKVDILGVYLYKTAFAFNDLGKAAAISVVLFIII
                     FAVILLTRKRVNLNGNK"
     gene            complement(67678..68970)
                     /locus_tag="IT892_000062"
                     /pseudo
     CDS             complement(67678..68970)
                     /locus_tag="IT892_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415826.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
     gene            complement(68984..70663)
                     /locus_tag="IT892_000063"
     CDS             complement(68984..70663)
                     /locus_tag="IT892_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415825.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAP3133319.1"
                     /translation="MKQKITDYLDEIYGGTFTATHLQKLVTRLESAKRLITQRRKKHW
                     DESDVVLITYADQFHSNDLKPLPTFNQFYHQWLQSIFSHVHLLPFYPWSSDDGFSVID
                     YHQVASEAGEWQDIQQLGECSHLMFDFVCNHMSAKSEWFKNYLQQHPGFEDFFIAVDP
                     QTDLSAVTRPRALPLLTPFQMRDHSTRHLWTTFSDDQIDLNYRSPEVLLAMVDVLLCY
                     LAKGAEYVRLDAVGFMWKEPGTSCIHLEKTHLIIKLLRSIIDNVAPGTVIITETNVPH
                     KDNIAYFGAGDDEAHMVYQFSLPPLVLHAVQKQNVEALCAWAQNLTLPSSNTTWFNFL
                     ASHDGIGLNPLRGLLPESEILELVEALQQEGALVNWKNNPDGTRSPYEINVTYMDALS
                     RRESSDEERCARFILAHAILLSFPGVPAIYIQSILGSRNDYAGVEKLGYNRAINRKKY
                     HSKEITRELNDEATLRHAVYHELSRLITLRRSHNEFHPDNNFTIDTINSSVMRIQRSN
                     ADGNCLTGLFNVSKNIQHVNITNLHGRDLISEVDILGNEITLRPWQVMWIK"
     gene            complement(70876..71190)
                     /gene="pspE"
                     /locus_tag="IT892_000064"
     CDS             complement(70876..71190)
                     /gene="pspE"
                     /locus_tag="IT892_000064"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase PspE"
                     /protein_id="HAP3133320.1"
                     /translation="MFKKGLLALALVFSLPVFAAEHWIDVRVPEQYQQEHVQGAINIP
                     LKEVKERIATAVPDKNDTVKVYCNAGRQSGQAKEILSEMGYTHVENAGGLKDIAMPKV
                     KG"
     gene            complement(71265..71486)
                     /gene="pspD"
                     /locus_tag="IT892_000065"
     CDS             complement(71265..71486)
                     /gene="pspD"
                     /locus_tag="IT892_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="HAP3133321.1"
                     /translation="MNTRWQQAGQKVKPGFKLAGKLVLLTALRYGPAGVAGWAIKSVA
                     RRPLKMLLAVALEPLLSRAANKLAQRYKR"
     gene            complement(71495..71854)
                     /gene="pspC"
                     /locus_tag="IT892_000066"
     CDS             complement(71495..71854)
                     /gene="pspC"
                     /locus_tag="IT892_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="HAP3133322.1"
                     /translation="MAGINLNKKLWRIPQQGMVRGVCAGIANYFDVPVKLVRILVVLS
                     IFFGLALFTLVAYIILSFALDPMPDNMAFGEQLPSSSELLDEVDRELAASETRLREME
                     RYVTSDTFTLRSRFRQL"
     gene            complement(71854..72078)
                     /gene="pspB"
                     /locus_tag="IT892_000067"
     CDS             complement(71854..72078)
                     /gene="pspB"
                     /locus_tag="IT892_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="HAP3133323.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRSGRSELSQSEQQRLA
                     QLADEAKRMRERIQALESILDAEHPNWRDR"
     gene            complement(72132..72800)
                     /gene="pspA"
                     /locus_tag="IT892_000068"
     CDS             complement(72132..72800)
                     /gene="pspA"
                     /locus_tag="IT892_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="HAP3133324.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVR
                     STSARALAEKKQLTRRIEQASAREVEWQEKAELALLKEREDLARAALIEKQKLTDLIK
                     SLEHEVTLVDDTLARMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGK
                     LDEAMARFESFERRIDQMEAEAESHSFGKQKSLDDQFAELKADDAISEQLAQLKAKMK
                     QDNQ"
     gene            72967..73944
                     /gene="pspF"
                     /locus_tag="IT892_000069"
     CDS             72967..73944
                     /gene="pspF"
                     /locus_tag="IT892_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415819.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="HAP3133325.1"
                     /translation="MAEYKDNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKEL
                     IASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGG
                     TLFLDELATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGT
                     FRADLLDRLAFDVVQLPPLRERESDIMLMAEYFAIQMCREIKLPLFPGFTERARETLL
                     NYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKRRPPEDAIAVSETTSLPTLP
                     LDLREFQMQQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI"
     gene            complement(74064..75329)
                     /locus_tag="IT892_000070"
     CDS             complement(74064..75329)
                     /locus_tag="IT892_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate aminotransferase PuuE"
                     /protein_id="HAP3133326.1"
                     /translation="MSNNEFHQRRLSATPRGVGVMCNFFAQSAENATLKDVEGNEYID
                     FAAGIAVLNTGHRHPDLVAAVEQQLQQFTHTAYQIVPYESYVTLAEKINALAPVSGQA
                     KTAFFTTGAEAVENAVKIARAHTGRPGVIAFSGGFHGRTYMTMALTGKVAPYKIGFGP
                     FPGSVYHVPYPSDLHGISTQDSLDAIERLFKSDIEAKQVAAIIFEPVQGEGGFNVAPK
                     ELVAAIRRLCDEHGIVMIADEVQSGFARTGKLFAMDHYADKPDLMTMAKSLAGGMPLS
                     GVVGNANIMDAPAPGGLGGTYAGNPLAVAAAHAVLNIIDKESLCERANQLGQRLKNTL
                     IDAKESVPAIAAVRGLGSMIAVEFNDPQTGEPSAAIAQKIQQRALAQGLLLLTCGAYG
                     NVIRFLYPLTIPDAQFDAAMKILQDALSD"
     gene            complement(75367..76647)
                     /locus_tag="IT892_000071"
     CDS             complement(75367..76647)
                     /locus_tag="IT892_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAP3133327.1"
                     /translation="MTEHTSSYYAASANKYAPFDTLNESITCDVCVVGGGYTGLSSAL
                     HLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYSRDIDVIEKSYGMDTARMLGSMMFE
                     GGEIIRERIKRYQIDCDYRPGGLFVAMNDKQLATLEEQKENWERYGNKQLELLDANAI
                     RREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLNGGRVYELSAVTQIQHTTPAVV
                     RTAKGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGTQVITTERLSEDLARSLIPKNY
                     CVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVERLVVPKLLKTFPQLKGVKIDY
                     RWTGNFLLTLSRMPQFGRLDTNIYYMQGYSGHGVTCTHLAGRLIAELLRGDAERFDAF
                     ANLPHYPFPGGRTLRVPFTAMGAAYYSLRDRLGV"
     gene            complement(76649..78136)
                     /gene="puuC"
                     /locus_tag="IT892_000072"
     CDS             complement(76649..78136)
                     /gene="puuC"
                     /locus_tag="IT892_000072"
                     /EC_number="1.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase PuuC"
                     /protein_id="HAP3133328.1"
                     /translation="MNFHHLAYWQDKALSLAIENRLFINGEYTAAAENETFETVDPVT
                     QAPLAKIARGKSVDIDRAMSAARGVFERGDWSLSSPAKRKAVLNKLADLMEAHAEELA
                     LLETLDTGKPIRHSLRDDIPGAARAIRWYAEAIDKVYGEVATTSSHELAMIVREPVGV
                     IAAIVPWNFPLLLTCWKLGPALAAGNSVILKPSEKSPLSAIRLAGLAKEAGLPDGVLN
                     VVTGFGHEAGQALSRHNDIDAIAFTGSTRTGKQLLKDAGDSNMKRVWLEAGGKSANIV
                     FADFPDLQQAASATAAGIFYNQGQVCIAGTRLLLEESIADEFLALLKQQAQNWQPGHP
                     LDPATTMGTLIDCAHADSVHSFIREGESKGQLLLDGRNAGLAAAIGPTIFVDVDPNAS
                     LSREEIFGPVLVVTRFTSEEQALQLANDSQYGLGAAVWTRDLSRAHRMSRRLKAGSVF
                     VNNYNDGDMTVPFGGYKQSGNGRDKSLHALEKFTELKTIWISLEA"
     gene            complement(78411..78968)
                     /gene="puuR"
                     /locus_tag="IT892_000073"
     CDS             complement(78411..78968)
                     /gene="puuR"
                     /locus_tag="IT892_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator PuuR"
                     /protein_id="HAP3133329.1"
                     /translation="MSDEGLAPGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDK
                     VSPAISTLQKLLKVYGLSLSEFFSEPEKPDEPQVVINQDDLIEMGSQGVSMKLVHNGN
                     PNRTLAMIFETYQPGTTTGERIKHQGEEIGTVLEGEIVLTINGQDYHLVAGQSYAINT
                     GIPHSFSNTSAGICRIISAHTPTTF"
     gene            complement(78995..79759)
                     /gene="puuD"
                     /locus_tag="IT892_000074"
     CDS             complement(78995..79759)
                     /gene="puuD"
                     /locus_tag="IT892_000074"
                     /EC_number="3.5.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415814.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase"
                     /protein_id="HAP3133330.1"
                     /translation="MENIMNNPVIGVVMCRNRLKGHATQTLQEKYLNAIIHAGGLPIA
                     LPHALAEPSLLEQLLPKLDGIYLPGSPSNVQPHLYGENGDEPDADPGRDLLSMAIINA
                     ALERRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAPSHEVQ
                     VEEGGLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLVEAVSVINHPFALG
                     VQWHPEWNSSEYALSRILFEGFITACQHHIAEKQRL"
     gene            79971..81389
                     /locus_tag="IT892_000075"
     CDS             79971..81389
                     /locus_tag="IT892_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415813.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HAP3133331.1"
                     /translation="METNIVEVENFVQQSEERRGSAFTQEVKRYLERYPNTQYVDVLL
                     TDLNGCFRGKRIPVSSLKKLEKGCYFPASVFAMDILGNVVEEAGLGQEMGEPDRTCVP
                     VLGSLTPSAADPEFIGQMLLTMVDEDGAPFDVEPRNVLNRLWQQLRQRGLFPVVAVEL
                     EFYLLDRQRDAEGYLQPPCAPGTDDRNTQSQVYSVDNLNHFADVLNDIDELAQLQLIP
                     ADGAVAEASPGQFEINLYHTDNVLEACDDALALKRLVRLMAEKHKMHATFMAKPYEEH
                     AGSGMHIHISMQNNRGENVLSDAEGEDSPLLKKMLAGMIDLMPSSMALLAPNVNSYRR
                     FQPGMYVPTQASWGHNNRTVALRIPCGDRHNHRVEYRVAGADANPYLVMAAIFAGILH
                     GLDNELPLQEEVEGNGLEQEGLPFPIRQSDALGEFIENDHLRRYLGERFCHVYHACKN
                     DELLQFERLITETEIEWMLKNA"
     gene            81538..81702
                     /locus_tag="IT892_000076"
     CDS             81538..81702
                     /locus_tag="IT892_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133332.1"
                     /translation="MPMIKSPHGEGGCVCAPPATDWTPPPLLPLLNRFDFRSTRPQTL
                     LRRGGSNYGY"
     gene            81692..83077
                     /gene="puuP"
                     /locus_tag="IT892_000077"
     CDS             81692..83077
                     /gene="puuP"
                     /locus_tag="IT892_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415812.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PuuP"
                     /protein_id="HAP3133333.1"
                     /translation="MAINSPLNIAAQPGKTRLRKSLKLWQVVMMGLAYLTPMTVFDTF
                     GIVSGISDGHVPASYLLALAGVLFTAISYGKLVRQFPEAGSAYTYAQKSINPHVGFMV
                     GWSSLLDYLFLPMINVLLAKIYLSALFPEVPPWVWVVTFVAILTAANLKSVNLVANFN
                     TLFVLVQISIMVVFIFLVVQGLHKGEGVGTVWSLQPFISENAHLIPIITGATIVCFSF
                     LGFDAVTTLSEETPDAARVIPKAIFLTAVYGGVIFIAASFFMQLFFPDISRFKDPDAA
                     LPEIALYVGGKLFQSIFLCTTFVNTLASGLASHASVSRLLYVMGRDNVFPERVFGYVH
                     PKWRTPALNVIMVGIVALSALFFDLVTATALINFGALVAFTFVNLSVFNHFWRRKGMN
                     KSWKDHFHYLLMPLVGALTVGVLWVNLESTSLTLGLVWASLGGAYLWYLIRRYRKVPL
                     YDGDRTPVSET"
     gene            83211..83456
                     /locus_tag="IT892_000078"
     CDS             83211..83456
                     /locus_tag="IT892_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmjA family protein"
                     /protein_id="HAP3133334.1"
                     /translation="MNHDIPLKYFDIADEYATECAEPVAEAERTPLAHYFQLLLTRLM
                     NNEEISEEAQHEMAAEAGINPVRIDEIAEFLNQWGNE"
     gene            83769..85412
                     /gene="sapA"
                     /locus_tag="IT892_000079"
     CDS             83769..85412
                     /gene="sapA"
                     /locus_tag="IT892_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein SapA"
                     /protein_id="HAP3133335.1"
                     /translation="MRQVLSSLLVIAGLVSGQAIAAPESPPHADIRDSGFVYCVSGQV
                     NTFNPSKASSGLIVDTLAAQFYDRLLDVDPYTYRLMPELAESWEVLDNGATYRFHLRR
                     DVPFQKTDWFTPTRKMNADDVVFTFQRIFDRNNPWHNVNGSNFPYFDSLQFADNVKSV
                     RKLDNHTVEFRLAQPDASFLWHLATHYASVMSAEYARKLEKEDRQEQLDRQPVGTGPY
                     QLSEYRAGQFIRLQRHDDFWRGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAAS
                     QLSILRDDPRLRLTLRPGMNVAYLAFNTAKPPLNNPAVRHALALAINNQRLMQSIYYG
                     TAETAASILPRASWAYDNEAKITEYNPAKSREQLKSLGLENLTLKLWVPTRSQAWNPS
                     PLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMSHDLTLSGWATDSNDPDSFFRP
                     LLSCAAIHSQTNLAHWCDPKFDSVLRKALSSQQLAARIEAYDEAQSILAQELPILPLA
                     SSLRLQAYRYDIKGLVLSPFGNASFAGVYREKQDEVKKP"
     gene            85409..86374
                     /gene="sapB"
                     /locus_tag="IT892_000080"
     CDS             85409..86374
                     /gene="sapB"
                     /locus_tag="IT892_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapB"
                     /protein_id="HAP3133336.1"
                     /translation="MIIFTLRRILLLIVTLFLLTFVGFSLSYFTPHAPLQGASLWNAW
                     VFWFNGLIHWDFGVSSINGQPIAEQLKEVFPATMELCILAFGFALIVGIPVGMIAGIT
                     RHKWQDNLINAIALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKPITGFA
                     LIDAWLSDSPWRDEMIMSAIRHMILPVITLSVAPTTEVIRLMRISTIEVYDQNYVKAA
                     ATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAI
                     RQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEWYALR"
     gene            86361..87251
                     /gene="sapC"
                     /locus_tag="IT892_000081"
     CDS             86361..87251
                     /gene="sapC"
                     /locus_tag="IT892_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapC"
                     /protein_id="HAP3133337.1"
                     /translation="MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCI
                     FGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGA
                     FVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
                     AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVT
                     EITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMIS
                     VLLVNLLGDGVRRAIIAGVE"
     gene            87251..88243
                     /gene="sapD"
                     /locus_tag="IT892_000082"
     CDS             87251..88243
                     /gene="sapD"
                     /locus_tag="IT892_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapD"
                     /protein_id="HAP3133338.1"
                     /translation="MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGS
                     GKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCL
                     DPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
                     EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHD
                     LQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLN
                     TLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE"
     gene            88245..89051
                     /gene="sapF"
                     /locus_tag="IT892_000083"
     CDS             88245..89051
                     /gene="sapF"
                     /locus_tag="IT892_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapF"
                     /protein_id="HAP3133339.1"
                     /translation="MIETLLEVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLA
                     IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPSTSLN
                     PRQRISQILDFPLRLNTDLEPEQRRKQIIETMRMVGLLPDHVSYYPHMLAPGQKQRLG
                     LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS
                     DQVLVMHQGEVVERGSTADVLASPLHELTKRLIAGHFGEALTADAWRKDR"
     gene            89119..89472
                     /locus_tag="IT892_000084"
     CDS             89119..89472
                     /locus_tag="IT892_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF559 domain-containing protein"
                     /protein_id="HAP3133340.1"
                     /translation="MIDKIKSNARDLRRNLTLQERKLWRYLRSRRFSDFKFRRQHPVG
                     SYILDFACCSARVVVELDGGQHDLAVAYDSRRTSWLESQGWTVLRFWNNEIDCNEETV
                     LENILQELNRRSPSP"
     gene            89840..90628
                     /gene="fabI"
                     /locus_tag="IT892_000085"
     CDS             89840..90628
                     /gene="fabI"
                     /locus_tag="IT892_000085"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAP3133341.1"
                     /translation="MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL
                     KGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDG
                     DYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG
                     LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR
                     TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK"
     gene            90772..91899
                     /locus_tag="IT892_000086"
     CDS             90772..91899
                     /locus_tag="IT892_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415803.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CMD domain-containing protein"
                     /protein_id="HAP3133342.1"
                     /translation="MEQRHITGKSHWYHETQSSTTEYDVLPLVPEAAKVSDPFLLDVI
                     LEKETLAPFLSWLDPARVLAVDLFPDQLTVTRSQTFTAYERLSTALTVAQVCGVQRLC
                     NYYSARLTPLPGPDSTRESNHRLAQITQYARQLASSPSIIDNRSRQHLNDVGLTAWDC
                     VIISQIIGFIGFQARTIATFQAYLGHPVRWLPGLEIQNYADASLFADESLRWRSSYEV
                     EKLPEEHTKSSTAELCQLAEILSLHPISLSLLEKLLNSTRGNTQPDNQLAALLCARIN
                     GSPACFATCMDSSNEYKKISTLMRKGENEINQWADRHSVERATVQAIQWLTRAPDRFS
                     AAQFSPLLEHEKSSTQIINLLVWSGLCGWINRLKIALGETY"
     gene            91967..93901
                     /gene="rnb"
                     /locus_tag="IT892_000087"
     CDS             91967..93901
                     /gene="rnb"
                     /locus_tag="IT892_000087"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease II"
                     /protein_id="HAP3133343.1"
                     /translation="MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSY
                     FIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPD
                     HPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP
                     WWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALP
                     DDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRAN
                     EVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIA
                     EQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA
                     MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFC
                     KLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINH
                     RLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAA
                     EIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVI
                     DVTIAEVRMETRSIIARPVA"
     gene            complement(93979..94083)
                     /locus_tag="IT892_000088"
     CDS             complement(93979..94083)
                     /locus_tag="IT892_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133344.1"
                     /translation="MTYMKLTAAKRIVFFIYLFVIQFWKNASFQTKVS"
     gene            94137..96122
                     /gene="pdeR"
                     /locus_tag="IT892_000089"
     CDS             94137..96122
                     /gene="pdeR"
                     /locus_tag="IT892_000089"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HAP3133345.1"
                     /translation="MKTVRESTTLYNFLGSHNPYWRLTESSDVLRFSTTETTEPDRTL
                     QLSAEQAARIREMTVITSSLMMSLTVDESDLSVHLVGRKINKREWAGNASAWHDTPAV
                     ARDLSHGLSFAEQVVSEAHSAIVILDSRGNIQRFNRLCEDYTGLKEHDVIGQSVFKLF
                     MSRREAAASRRNNRVFFRSGNAYEVELWIPTCKGQRLFLFRNKFVHSGSGKNEIFLIC
                     SGTDITEERRAQERLRILANTDSITGLPNRNAMQDLIDHAINHADNNKVGVVYLDLDN
                     FKKVNDAYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLVLASNTSQSALEAMA
                     SRILTRLRLPFRIGLIEVYTSCSVGIALSPEHGSDSTAIIRHADTAMYTAKEGGRGQF
                     CVFTPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPER
                     GLIPPLDFISYAEESGLIVPLGRWVILDVVRQVAKWRDKGINLRVAVNISARQLADQT
                     IFTALKQVLQELNFEYCPIDVELTESCLIENDELALSVIQQFSQLGAQVHLDDFGTGY
                     SSLSQLARFPIDAIKLDQVFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKE
                     DAFLTKNGINERQGFLFAKPMPAVAFERWYKRYLKRA"
     gene            96270..96443
                     /locus_tag="IT892_000090"
     CDS             96270..96443
                     /locus_tag="IT892_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133346.1"
                     /translation="MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVA
                     ESTPDIPKAPWEI"
     gene            96533..97282
                     /locus_tag="IT892_000091"
     CDS             96533..97282
                     /locus_tag="IT892_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP3133347.1"
                     /translation="MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKL
                     SYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLA
                     RTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
                     SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVE
                     RFNRVITDSKIRASDLMHLEHSKLTVHVVDI"
     gene            97551..97769
                     /gene="osmB"
                     /locus_tag="IT892_000092"
     CDS             97551..97769
                     /gene="osmB"
                     /locus_tag="IT892_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmB"
                     /protein_id="HAP3133348.1"
                     /translation="MFVTSKKMTAAVLAITLAMSLSACSNWSKRDRNTAIGAGAGALG
                     GAVLTDGSTLGTLGGAAVGGVIGHQVGK"
     gene            complement(97895..98221)
                     /gene="yciH"
                     /locus_tag="IT892_000093"
     CDS             complement(97895..98221)
                     /gene="yciH"
                     /locus_tag="IT892_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HAP3133349.1"
                     /translation="MSDSNSRLVYSTETGRIDEPKAAPVRPKGDGVVRIQRQTSGRKG
                     KGVCLITGVDLDDAELTKLAAELKKKCGCGGAVKDGVIEIQGDKRDLLKSLLEAKGMK
                     VKLAGG"
     gene            complement(98221..98958)
                     /gene="pyrF"
                     /locus_tag="IT892_000094"
     CDS             complement(98221..98958)
                     /gene="pyrF"
                     /locus_tag="IT892_000094"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAP3133350.1"
                     /translation="MTLTASSSSRAVTNSPVVVALDYHNRDDALAFVDKIDPRDCRLK
                     VGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASG
                     GARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLVDLGMTLSPADYAERLAALTQK
                     CGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALSAGVDYM
                     VIGRPVTQSVDPAQTLKAINASLQRSA"
     gene            complement(99152..>100259)
                     /gene="lapB"
                     /locus_tag="IT892_000095"
     CDS             complement(99152..>100259)
                     /gene="lapB"
                     /locus_tag="IT892_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HAP3133351.1"
                     /translation="RSAQQNKQDEANRLSRDYVAGVNFLLSNQQDKAVDLFLDMLKED
                     TGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLTYEQRLLAIQQLGRDYMAAGLY
                     DRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKAIDVAERLVKLGKDKQRVEIAH
                     FYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSIMMGRVFMAKGEYAKAVESLQR
                     VISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAVEENTGADAELMLADIIEARDG
                     SEAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRAKESLMVLRDMVGEKVRSKPRY
                     RCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL"
BASE COUNT        24355 a        26333 c        24713 g        24858 t
ORIGIN      
        1 atactcaaat aaataaagca gagcttaaac ataactctgc tttataatta aagggacaaa
       61 ataattttac atctgttact gtttcggtcg cagattctca tcaaatacca ggcgtttcct
      121 gccaggttca atttcccgca atggctcgac ttgatgtaac gtctgcttac agcgtgtcac
      181 cagcacctgg tactcatgcg taccctgctt tttccatgcc aactcctgct cactgagttc
      241 acgaatcgct ttcgccgggc tgccgacaat caggtaatta gctggcattt ctgctttggc
      301 tttcacaaat gcggatgcac caacaatgct gttctcgcca atcaccgcac cgtccatcac
      361 taccgcgttc attcccacta atgcattgcg gcggataatg cagccgtgaa ggatagcgct
      421 atgaccaata tgtccatctt ctcctacaac agtatcctgc tcgggaaaac cgtgcataac
      481 gcaattatcc tgaatgttcg cgccatcttt caccacgata cgaccaaaat cgccacgcag
      541 gctggcattt ggcccaacgt aaacgccctt gtcgagaata acatcgccga tcaataccgc
      601 tgtcggatgg acaaaactct cttctggcac aaccggagtc agaccgtcta tctgataaat
      661 tggcataacg cctcctgttc aatattcaag ccgccaaaac gttgaaaata caggcttccc
      721 ggcgcaggca gttcaccgac cgaggtttca cctttttcac taacgaacgc taaagcagca
      781 ggcgctacgc gctgataaat gttgatacac agctgacgcg ccgtatgccc tgcccagtgt
      841 gccggaagca actcctccgg caacaatggg tctttaagga cgacacggcg ataaaaatgg
      901 atcagtaaaa gctgaatatg aaatgcccgc tccggggtta actcgtctgc cgcctctttt
      961 aaaagcggca ccagcgggcg gaatgactga ataaaggttt cgtacatggc attttgttca
     1021 gttaaatgcc agcactcttc tactctggca cgcagtgctg cgcgagaaag cgccagtggt
     1081 atttgcgctt caaaacaaat cacgttatcc gccacacccg cttcatgcaa aagtgtctgt
     1141 acatcggcca gtttttgcga cggcgatgcc atcaggctgg gtgccagtgc gccaaaacct
     1201 tgccagatca actgcttttt gacatcagcc agcgttgatt tatctaaacc ttccgagagc
     1261 aacaggagcc atttaccatc ccatgcaggt tgctctgcgc gataaatttt actttctgcc
     1321 cgtcgcgtca ggcgcaagcc tttatcactg aggctataga aactgcgtcg cccgatgcgg
     1381 gaaacatcca gccagccttc tttattaaga cgaaacaaag cggtgcgcac gaaacgctca
     1441 ccaaatccca gcccttccag caaagcagcc agactaccca accagatttc accaccacga
     1501 tgggaaagcg aatcaccata cagagaggag atcaaagatg tgccactgac cggaacagcg
     1561 tttacagcat gttggataaa agtatcaagt ttactcattc gcttcagtct gttgttattg
     1621 ttgtgattta tgaatcatag cacaggtcgt atcgacttct ggccctggcg ctttacccca
     1681 ccagggccag acgatacgtc aggcaccaac aatattgcgc agatcaaaca cccgacacgc
     1741 cttgccttct gaacgcggga tactgccaca gttaacgatc atcacatcgg tagagatccc
     1801 caccatcgac ttaatccgat ggcgcagctg gtggcatacc tggcaacgct gctcatgcgt
     1861 caatgtcagg ctactttctt tcaactccac tttcacagaa agtgaatcaa gatgcccccg
     1921 gcggttcacc tccagttggt aatgcggcga taaatgttcg aatttgacaa tctcttcttc
     1981 cagttgtgac ggaaagacat ttacaccgcg aataatcaac atgtcatcgc tgcgtccgct
     2041 gatgcgatcc atgcggcgca tagtccgcgc cgttcctggt aacagtcggg ttaaatcacg
     2101 cgtgcggtaa cgaatgaccg gcaatgcttc tttggtcagc gtggtgaata acagttcgcc
     2161 atgttcacca tcggcaagcg gtgtgccgtc atgaggatta acaatttcag gatagaaatg
     2221 atcttcccaa atggttgggc cgtcggtagt ttccagacac tccatcgcca cccccggccc
     2281 catcacttct gacaggccat aaatatccag tgcggtgatc cccaggcgac gctcaatctc
     2341 tttacgcatg gcctgtgtcc acggctcagc accaaatact ccaacccgca gcgagcaacc
     2401 gctggcatca ccgcccaact gccgctccag ctcttcaatc aggttaaggc aataagatgg
     2461 cgtaaccatg atcatatctg gttgaaaatc acggatcagt tgcgcttgtt tttccgtctg
     2521 cccgccagac atcgggatca ccgtagcgcc cagacgttcg gcaccatagt gcgcacccag
     2581 cccaccagta aacaggccgt aaccataggc aacatgaatt ttgtctttgg gcgagccccc
     2641 tgccgcacgc aaagaacgcg ctacaatatt ggcccagtta tcaatatcgt tttgcgtata
     2701 gccgacaact gtcggtttac ctgtggttcc cgaagaagca tgaatgcgca ccacttgttc
     2761 cattggcacg gcaaaggtgt caaagggata gttgtcgcgc agatcctgtt tggtggtaca
     2821 gggaaattta cgcaggtctg aaagttccct gaaatcatca ggatgtacgc ctgctgcgtc
     2881 gaatttgcgc cgatacatcg gcacattttc atacgcgtgt ttgagcgtcc atttcagacg
     2941 ctgtgtttgc aacgcctgta actcatcaac agacgcggtt tcaatcgggt caagctttgt
     3001 attggttatc attgtagggt actcgcaggt tgatatgctc aaacacgctc cagaatcatg
     3061 gcgatgccct gaccgacacc gatgcacatg gtgcacaatg cgtaacgacc gttacgccga
     3121 tgcagctcat ggctggcagc cagtgccagg cgggcaccac tcattcccaa cggatggcct
     3181 aaggcgatag cgcctccgtt ggggttaaca tgtggggcat catcaggcag ccccaattcg
     3241 cgtagtacac ccaacgcctg ggccgcgaac gcttcgttca gttcaatcac gtccatatcg
     3301 tgaatactca gccctgcgcg ttccagcacc cggcgagttg caggcaccgg accaagcccc
     3361 atcaggcgcg gttccacccc ggcggttgcc atggctacga tacgcgcccg cggtgtcagt
     3421 ccttgcgctg ctgccatctg ttcactggca ataatcaacg cagcggctcc gtcattcacc
     3481 ccggaagcat tgcctgcggt aatcacccca ttggcacgaa atggtgcttt taacccacgt
     3541 aactgttcca gcgtcgtttc cgggcgcaga tgctcatcat gttgtatttc tgttacaaca
     3601 cctttcttgt ttttcaacac aaccggaaca atctcctcag ccagaatgcc tgaggattgc
     3661 gcttttgccg tacgttgctg actgcgtagc gcaaaactat cttgatcttc tcgtgagatt
     3721 tttaacagtt cagctacatt ctctgccgtt tccggcatgc tgtcagttcc aaattgctga
     3781 gccatgagcg ggttcacaaa tcgccagcca atagtggtat cgaacatctc agcctgacga
     3841 gaaaatgcac tggctgcctt gcccataaca aacggtgccc gtgacattga ctccacgcca
     3901 ccggcgatca gcaaatcgcc atcgcccgct ttaatcgccc gtgcggcaaa ccccagtgcg
     3961 tccagcccgg aaccacacaa gcggttaatg gttgtgccgg aaacactctg cggcagcccc
     4021 gccagtaaag tcgccatccg ggctacgtta cggttatctt ctcccgcctg attagcacag
     4081 ccgaggatca catcatcgat acactccgca tcgagacgcg ggtttcgcac cagcagttcc
     4141 cgcaaaggga tagcagccag atcatcagcc cgaacacttg ataatgcccc gccgtagcga
     4201 ccaattggcg tacgaattcc gtcacaaata aaggcttcac gcatcaggct tctcctgtaa
     4261 tggtgccgcc gatgcggtga gatttaccgc gaaacagcgc aaccgttttt tgttgttggt
     4321 taacaatttc gatgtcgtaa acaccggttt gcttgccctg atgacgtacc tgcgcagtag
     4381 cagttaaggt gtctccggca aagcctggac gcaaaaaatc aatcgtgcag gcagaagcga
     4441 cggctgccag cccctggcta ttgcaggcgt aggcaaaggc agtatcagcc agtgaaaata
     4501 gctgcccgcc gtggcaactt tgatgaccgt taagcatttg tgcagtgacg gtcatggtca
     4561 ctacagcaaa gccttcatcc attgagataa tgtcgatgcc aagcgctttg gcgcaggcat
     4621 cgttctcata cattgcatgg gcattttgcc aggccttatg actcataacc gctctccaga
     4681 agcgcccgtt ggcgcagcaa tgaacatggg cgatagcgtt cttcgccata gtgatgctgt
     4741 agattttcaa ggagccttaa tattcgctgc cagccaagtt gcgctcccca ggcaagtggg
     4801 ccatatggat aattcacccc aagacgcatg gcggtatcga tatcctgttc agaggccacg
     4861 cctttttgaa gcgcatcaag ggcttcattg atgatcattg ctaccgttcg ccaaatcagc
     4921 attcctgggt aatctgcaat ttgcagcact gttttgccct gctgttgcag gtaataaatg
     4981 gccttgcggg tcgctgagtc cgggttcacc gctgcagcag caatggtcac caccttgccc
     5041 gccattttat cgatcactac caccgggcgt gccagtcgta ttgccagcgc ctgtgccgtc
     5101 tcgccttgtg tctcaatcaa taaaacatcg tcaatttccg tgacaccgtc acttttcttt
     5161 tctactttca ttgggctaaa actgtcgctt accgcttcca ggccaacaac tgcctcacgt
     5221 tccgcgcgcc agtcgtacac gcccagccca cttttcttgc ccaaccgtcc accaatcacc
     5281 agttcctgtt gcaccagcga aggtaaaaaa cgacgctcct gccagaaagc gttaaacacc
     5341 gaacaggtga cagcaaaatt gacgtcctga ccaatcagat cggttaattc cagcggcccc
     5401 atcgggaaac cagcgccatc gcgaagtgca gcgtcaatca cttctggtgc agcaacctgc
     5461 tcttccagtg cccgccaggc ctcggaataa taaggacgcg caacacggtt aacgataaat
     5521 ccaggagtcg aatgacagcg cacaggctgc ttaccccaac tcaacgttag ttcacacaac
     5581 tgctcaacaa cttccgccgc cgttgccagc ccactgacca cctccaccaa cttcatcacc
     5641 ggtgccgggt taaaaaaatg cagccccgca acacgttcag gattttttat ctccgcagca
     5701 atcgcggtta tagagattga cgaagtgtta gtggtcaata gcgtttgtgg cgggcaaact
     5761 tccgccagct gtgcaaagag cgcttttttg acttccagac gttcagacgc cgcttcaatg
     5821 accaggtccg cagctgccag cgcgtgaata tcggtcaccg ggatcaggcg tttcaatgtg
     5881 cgttcacagg tttcagcagt cagttttccc cgcgtcacgc gtgaatttag ccgcgcgtgt
     5941 atcccgtcga ttgcgcgggt cagcgcttca gcagaaatgt catacagtaa aacctggtgt
     6001 ccatgactgg cagcaacttc agcaatgcct gcccccatgg tgccgctccc aatcactgcc
     6061 acagtttgca catttatcat catgctattt ccccgtgaac tgcggtgagc gtttagccag
     6121 gaacgcactg acaccttcac gataatctgc gctccgtccg gcaagtcgct gatagtcacg
     6181 ttccagatcc agttgcgtat cgagcgtatt ggtttcagcg ctatttatcg cttgcttgat
     6241 aagtccaaga ccaaatgtcg gttgtgtcgc cagatgccgt gccagctgtt gcgcggtatc
     6301 tgccagcgtt tcatcatcaa caacctgcca gatcatcccc cattcgtgcg cctgttcagc
     6361 actcagttga ttccccagca gtgccagccc catggcgcgc gctcgtccgg caacgcgtgg
     6421 cagtaaccag gttccaccgc aatcgggtat taagcctaac ttactaaacg ccatgacgaa
     6481 ttttgctgaa cgggcagcaa taacgatgtc gccccccagt gccagtgttg cgcctgcccc
     6541 tgccgccacg ccattgactg cacagatcac cggttttggc agttttgcca ggcgacgtac
     6601 cagtgggtta tagaaacgtt caactgacat ccctaaatcc ggtgcggggc ctgtgggatc
     6661 aacgttacga tcgttaagat cctgaccagc acaaaatccg cgcccggcac ctgtaagtaa
     6721 caggcaacgg atagtgtcgt cgcgctcgac ctgtttcagg cactctgcca gttgtgcgtg
     6781 catctcatca ttaaaactgt tcaggcgttc cgggcggttg agcgttagtg tcatcacgcc
     6841 cttttctaca tgactgagga tgaattccat cattagcgtc ctttaaagtc gggcgtgcgt
     6901 ttttgtaaga aagcggagat gccttcatga cgatcttctg ttgccgccag caaggtgaat
     6961 aactgtcgct cctgggcaag tccggcttgc aaagccactt cctgcgactg gcgcagcgct
     7021 tgctttgccg cttgtaaggc cagcggcgag tgacgtgcca ttttcgatgc cagctgtaag
     7081 gcgtattcga gggttaaatc gctggggaag acgtcgctaa ccagcccggc ctgctgtgct
     7141 tgctgagcgg tgatactttc tccgctcagc accattttgc tggctaacga tttaccgaca
     7201 ctacggatta aacgttgcgt tccgcctgcg ccaggcatga tgccgagagt gatttccggc
     7261 aacccaaaac gcgcgttctc tccggcaacc accacatcgc acaacaatgc cagttcgcaa
     7321 cccgccccaa gcgcgtaacc attgacggct gcgataagtg gtttattaaa ggcctgcaat
     7381 cgcgcccata gctgcggacg tgtatcgttt aaggtggccg cgagatcttt ttctgccatt
     7441 tcgttgagat cggccccagc ggcaaaaaag cgtgcattac cggtaatcac acagaccgaa
     7501 atgctggtat cggtagccgc agcttccagt tcatttacca gttgcatcag cagggcatta
     7561 tttagcgcat tacgtgcggc gggacggtta agggtcagca acaatactcg ttgctgacgg
     7621 ctgacgatca gttcgctcat gccatcccct tcgcgtcaaa gtcaaccacc acatcgctgg
     7681 tcagcggcag tgcctggcaa ctcaacacat aacctgcggc cagttcatcc ggttccagac
     7741 tgtaattggt ttccatcgcc actttgccac gcagcacttt gcatttgcag gtcgcacaga
     7801 cgccgccttt gcaggcatag ggcagatccg ccccctggcg caatgccgca tcgagaatgc
     7861 tttcatcgtc ggcattaagc acgatttccc gatcccgccc atcctgacgt acagtcactt
     7921 tttgtccgtc actttgcacg ttaacgctac gtttgacgcg cgtgccaggc gtattaaacc
     7981 gctccagatg aatggtttta tctggcattc ccagtgcttt taaggcggtt tccgcgtcat
     8041 ccatcatcgc cgccggacca caaataaatg cctcatcata aagacgaaaa ttaatgagcg
     8101 aggccccaag tgactgtaat ttttcaccgt caatacgccc gtgaagcaga tcgctgtcga
     8161 gggtttcctg actgaaaatg cacaacaact gtaaacgctg aggatatttg tctttcaggt
     8221 ctgccagtgc ctggcgaaac atcatgctct ggctggtacg gttaccgtag atcagggtga
     8281 actgactttc aggctcggtt tgtaaagtgg tggcgataat cgccagcatt ggcgtaatac
     8341 ctgatcctgc tgcaattgcc agatagcgcc cctggcgttc ggcctgcggc tgatagccga
     8401 aatgcccctg cggcaccatg acctccagcg tcataccctg gcggatgtgt tcgcgggcat
     8461 agcgggagaa acgtccgcct tcaatggctt tcaccgccac actaatttcg ccaggcagat
     8521 agctgcggca aatggagtaa caacggcgta attcttcacc atcaaagctg gcttttaagg
     8581 tcaaatgttg accggggcga aagcgatacg cctcctgcaa aggctggggc accgcaaagg
     8641 taatggtcac cgcatcacgg gtttccgact cgacttttgc cactgttaag gaatgaaacg
     8701 ttgtcatggc atcctcaaat acatttgaaa taatcgaaag gttcgcggca actatcgcag
     8761 cggtacaatg ctttgcaggc cgtggaacca aattcactga taagtgtggt atggacgctg
     8821 gcgcagcgcg ggcaacgtac ttctggcggc aaatgggcat ggcaactgtg tccggcgggc
     8881 gggctaatgc catactctcg cagacgctca cgggcatcgg gggtcatcca gtcggtggtc
     8941 catgccgggt cgagttgcag cacaacctga acgggggtaa acccgttggt tgtcattgcc
     9001 tcacgtatcg cgccaatcaa atgttccgtt gccggacaac cggaatatgt cggcgtaaag
     9061 ccgatcaccc atccttctcc catctgtgtc acattacgca ccatgcctaa atcagtaatg
     9121 gtcagcaccg ggatctccgg gtccgggatc tggctgagta gcgcccatat ctcatgaacc
     9181 tgtggcggtg caatggtggc cagacgttgc atacccatct cctctgttac cattgctgac
     9241 cgggcaagac acgctggaga tactgcattt ctgccagcat gggtccaagg tgttcggtat
     9301 gcagtccttt tttaccgcca gtgcgatacg cctgctcttg cggtacgttc aatgtggctt
     9361 cgttgatccc ggcaaaaact tcggcttccc acgctgcgcg taaagtgcgt ggatcaaccg
     9421 caataccctc ttcactcagt gcaatatcaa tctcgtcggc atcgaacagt tcggcggtaa
     9481 aacgccacaa cttgttgatg gcctgctgca tcttttgccc tgatacgtca gtaccattgc
     9541 ccagtcgctc cagccagcca cgactaaaac gcaggtgata gcgcgcttct ttaattgctt
     9601 tggcagaaat cgccgccagt tgcggatcac ggctttccat cagacgggta aagagcgcca
     9661 catgccatgc atcgatgaaa tactggcgtg caatggtgtc ggcaaaattg ccgtttggtt
     9721 gttcaaccaa caataagttg ctgaactggc gctcgtctcg ggtgaaggcc agggtatctt
     9781 catcgccttc tcccgctaat tcagcggcat acgataagaa gttgcgtgcc tgacctaata
     9841 aatcgaggcc aatgtttgcc agtgcgagat cgatttccag ttccggtgcg tgaccgcacc
     9901 attcacccaa ccgctgggag agcaccaggc agttatcgcc caggcgcaag gtgtaagccg
     9961 ttaactgatt catttccgac ctcacatgtg ctcaatgcca tcagggatgg tgtaaaacgt
    10021 tggatggcga tagaccttgc tttcagccgg atcaaaaaat tcaccgcgtt cttccggttg
    10081 cgaggcaaca atttcactcg ccttcaccac ccaaattgaa catccttcgc tacgacgggt
    10141 gtaagcatca cgggcatttt ccagtgccat ccgctcatcg gcagcatgta aactgccaac
    10201 atggcggtgt gataagccct gtttgccacg cacgaaaact tcgtataacg gccagtaaac
    10261 attactcatt ttgaatctcc ttatgcgacc ttacgggcat gttgtttttg tgcatgggcc
    10321 agcgctgctt cccgtaccca ggtaccttct tcccaggctt tacgtttggc gtcgagcctc
    10381 tcctgattac aaattccgcg accgttaatt acttcgttaa actcctgcca gtcgatctca
    10441 ccaaagcggt agtgaccgct ttcagtgtca aaatgcagat ccgggtcagg aacggtcata
    10501 ccgagcattt caacctgtgg aacggtgtta tccacgaaac gctggcggag ttcgtcgttg
    10561 gtgaaacgtt tgattttcca ggtgagactt ctggcgctgt ttggcgagtt atcatcgttt
    10621 ggcccgaaca tcattaaggc tggccaccag aaacggttaa tggcgtcttg caacatctgc
    10681 ttttgagctt cgctgccctg cgccagtgcc atgcaggctt caaacccctg acgctggtga
    10741 aaactctctt ctttgcagat tttcaccatt gctctggcat acgggccata agaagtgcgg
    10801 cataacgcca cctgattgac gatcgctgcg ccatccacca gccagccgat aacaccgata
    10861 tcagcccaac tcaatgtcgg ataattaaag atggaggaat atttcatccg tccgtcgagc
    10921 attttttggt agatgtcttc tctggcgcag cccagtgttt cggcggcgct atagagatac
    10981 agaccatgac cggcttcatc ctgcactttg gccaacagaa tggctttacg ccgcaaggtt
    11041 ggtgcgcgag tgatccagtt accttcaggc aacataccaa caatctcgga gtgcgcatgc
    11101 tgcccaatct ggcggatcaa tgtctttcgg taagcatcgg gcatccagtc ctgtggctcg
    11161 atagccgttt cctgggctat ccgttgctca aagcgttctt cttgggtcac gtcatcacct
    11221 ttacgattcc agttttcgtg aattaattaa aaacacgaat cacattgttt tatgaaagtt
    11281 acacaatagt taagtaaaat cacaaatttt gtatgtttga actgtgacgg atttcgcacc
    11341 ctatttttat aaatcattat ttatcagtgc attaatgttt tccgcagttg ctatacagat
    11401 cgcatagtta acatttcgtt aaaagatccc ttgcttttta tgattcgcga tttaactatt
    11461 agcaacagaa atgtgaaaca tctggagagt agcgatgcag cagttagcca gtttcttatc
    11521 cggtacctgg cagtctggcc ggggccgtag ccgtttgatt caccacgcta ttagcggcga
    11581 ggcgttatgg gaagtgacca gtgaaggtct tgatatggcg gctgcccgcc agtttgccat
    11641 tgaaaaaggt gcccccgccc ttcgcgctat gacctttatc gaacgtgcgg cgatgcttaa
    11701 agcggtcgct aaacatctgc tgagtgaaaa agagcgtttc tatgctcttt ctgcgcaaac
    11761 aggcgcaacg cgggcagaca gttgggttga tattgaaggt ggcattggga cgttatttac
    11821 ttacgccagc ctcggtagcc gggagctgcc tgacgatacg ctgtggccgg aagatgaatt
    11881 gatcccctta tcgaaagaag gtggatttgc cgcgcgccat ttactgacct caaagtcagg
    11941 cgtggcagtg catattaacg cctttaattt cccctgctgg ggaatgctgg aaaagctggc
    12001 accaacgtgg ctgggcggaa tgccagccat catcaaacca gctaccgcga cggcccaact
    12061 gactcaggcg atggtgaaat caattgtcga tagtggtctt gttcccgaag gcgcaattag
    12121 tctgatctgc ggtagtgctg gcgacttgtt ggatcatctg gacagccagg atgtggtgac
    12181 tttcacgggg tcagcggcga ccggacagat gctgcgagtt cagccaaata tcgtcgccaa
    12241 atctatcccc ttcactatgg aagctgattc cctgaactgc tgcgtactgg gcgaagatgt
    12301 caccccggat caaccggagt ttgcgctgtt tattcgtgaa gttgtgcgtg agatgaccac
    12361 aaaagccggg caaaaatgta cggcaatccg gcggattatt gtgccgcagg cattggttaa
    12421 tgctgtcagt gatgctctgg ttgcgcgatt acagaaagtc gtggtcggtg atcctgctca
    12481 ggaaggcgtg aaaatgggcg cactggtaaa tgctgagcag cgtgccgatg tgcaggaaaa
    12541 agtgaacata ttgctggctg caggatgcga gattcgcctc ggtggtcagg cggatttatc
    12601 tgctgcgggt gccttcttcc cgccaacctt attgtactgt ccgcagccgg atgaaacacc
    12661 ggcggtacat gcaacagaag cctttggccc tgtcgcaacg ctgatgccag cacaaaacca
    12721 gcgacatgct ctgcaactgg cttgtgcagg cggcggtagc cttgcgggaa cgctggtgac
    12781 ggctgatccg caaattgcgc gtcagtttat tgccgacgcg gcacgtacgc atgggcgaat
    12841 tcagatcctc aatgaagagt cggcaaaaga atccaccggg catggctccc cactgccaca
    12901 actggtacat ggtgggcctg gtcgcgcagg aggcggtgaa gaattaggcg gtttacgagc
    12961 ggtgaaacat tacatgcagc gaaccgctgt tcagggtagt ccgacgatgc ttgccgctat
    13021 cagtaaacag tgggtgcgcg gtgcgaaagt cgaagaagat cgtattcatc cgttccgcaa
    13081 atattttgag gagctacaac caggcgacag cctgttgact ccccgccgca caatgacaga
    13141 ggccgatatt gttaactttg cttgcctcag cggcgatcgt ttctatgcac atatggataa
    13201 gattgctgct gccgaatcta ttttcggtga gcgggtggtg catgggtatt ttgtgctttc
    13261 tgcggctgcg ggtctgtttg tcgatgccgg tgtcggtccg gtcattgcta actacgggct
    13321 ggaaagcttg cgttttatcg aacccgtaaa gccaggcgat accatccagg tgcgtctcac
    13381 ctgtaagcgc aagacgctga aaaaacagcg tagcgcagaa gaaaaaccaa caggtgtggt
    13441 ggaatgggct gtagaggtat tcaatcagca tcaaaccccg gtggcgctgt attcaattct
    13501 gacgctggtg gccaggcagc acggtgattt tgtcgattaa tcggtgaatg aagggcaacg
    13561 gcgaatagtt gcccttttat ttcactaagt tttgtgacat tgtcacatta tgcatgatgt
    13621 gtacatctat tttcagggca tccactgtat gaaaagctgg cacacctgcc aaacaacctg
    13681 gcaggtgcag gcaatcccct ttgcatcagt actgataatg tgaacctgac taaaccgccc
    13741 acagagcgcg gttgctaaca agaacacaac atctgacgag gttaataatg ggaagcccct
    13801 ctctgtattc tgcccgtaaa acaaccctgg cgttggcagt cgccttaagt ttcgcctggc
    13861 aagcgccggt atttgcccac ggtggtgaag cgcatatggt gccaatggat aaaacgctta
    13921 aagaatttgg tgccgatgtg cagtgggacg actacgccca gctctttacc ctgattaaag
    13981 atggcgcgta cgtgaaagtg aagcctggtg cgcaaacagc aattgttaat ggtcagcctc
    14041 tggcactgca agtaccggta gtgatgaaag acaataaagc ctgggtttct gacaccttta
    14101 ttaacgatgt tttccagtcc gggctggatc aaacctttca ggtagaaaag cgccctcacc
    14161 cacttaatgc gctaactgcg gacgaaatta aacaggccgt tgaaattgtt aaagcttccg
    14221 cggacttcaa acccaatacc cgttttactg agatctccct gctaccgcca gataaagaag
    14281 ctgtctgggc gtttgcgctg gaaaacaaac cggttgacca gccgcgcaaa gccgacgtca
    14341 ttatgctcga cggcaaacat atcatcgaag cggtggtgga tctgcaaaac aacaaactgc
    14401 tctcctggca acccattaaa gacgcccacg gtatggtgtt gctggatgat ttcgccagtg
    14461 tgcagaacat tattaacaac agtgaagaat ttgccgctgc cgtgaagaaa cgcggtatta
    14521 ctgatgcgaa aaaagtgatt accacgccgc tgaccgtagg ttatttcgat ggtaaagatg
    14581 gcctgaaaca agatgcccgg ttgctcaaag tcatcagcta tcttgatgtc ggtgatggca
    14641 actactgggc acatcccatc gaaaacctgg tggcggtcgt tgatttagaa cagaaaaaaa
    14701 tcgttaagat tgaagaaggt ccggtagttc cggtgccaat gaccgcacgc ccatttgatg
    14761 gccgtgaccg cgttgctccg gcagttaagc ctatgcaaat cattgagcct gaaggtaaaa
    14821 attacaccat tactggcgat atgattcact ggcggaactg ggattttcac ctcagcatga
    14881 actctcgcgt cgggccgatg atctccaccg tgacttataa cgacaatggc accaaacgca
    14941 aagtcatgta cgaaggttct ctcggcggca tgattgtgcc ttacggtgat cctgatattg
    15001 gctggtactt taaagcgtat ctggactctg gtgactacgg tatgggcacg ctaacctcac
    15061 caattgctcg tggtaaagat gccccgtcta acgcagtgct ccttaatgaa accatcgccg
    15121 actacactgg cgtgccgatg gagatccctc gcgctatcgc ggtatttgaa cgttatgccg
    15181 ggccggagta taagcatcag gaaatgggcc agcccaacgt cagtaccgaa cgccgggagt
    15241 tagtggtgcg ctggatcagt acagtgggta actatgacta catttttgac tggatcttcc
    15301 atgaaaacgg cactattggc atcgatgccg gtgctacggg catcgaagcg gtgaaaggtg
    15361 ttaaagcgaa aaccatgcac gatgagacgg caaaagatga cacgcgctac ggcacgctta
    15421 tcgatcacaa tatcgtgggt actacacacc aacatattta taatttccgc ctcgatctgg
    15481 atgtagatgg cgagaataac agcctggtgg cgatggaccc agtggtaaaa ccgaatactg
    15541 ccggtggccc acgcaccagt accatgcaag ttaatcagta caacatcggc aatgaacagg
    15601 atgccgcaca gaaatttgat ccgggcacga ttcgtctgtt gagtaacccg aacaaagaga
    15661 accgcatggg caatccggtt tcctatcaaa ttattcctta tgcaggtggt actcacccgg
    15721 tagcaaaagg tgcccagttc gcgccggacg agtggatcta tcatcgttta agctttatgg
    15781 acaagcagct ctgggtaacg cgttatcatc ctggcgagcg tttcccggaa ggcaaatatc
    15841 cgaaccgttc tactcatgac accggtcttg gacaatacag taaggataac gagtcgctgg
    15901 acaacaccga cgccgttgtc tggatgacca ccggcaccac acatgtggcc cgcgccgaag
    15961 agtggccgat tatgccgacc gaatgggtac atactctgct gaaaccatgg aacttctttg
    16021 acgaaacgcc aacgctaggg gcgctgaaga aagataagtg attgtttcag acaaaaaaac
    16081 ggcaccaggt gccgtttttt acttatgagc gaaccagatt aataccgtac acacaccgac
    16141 ttagtttcac accaaccgtc cagccagtcg gggccaaaat cacggcccgt tcctgactgc
    16201 ttcatcccac caaacggtaa gttagcgtca attaaggtat ggctgtttac ccacaccgtc
    16261 cctgcctgta agcgatcgct atattccaga gcctgggaga gattttgcgt ccagacactg
    16321 gcagttaagc catattccgt gtcgtttgcc agttgtaacg cctcttctcc atccgctact
    16381 cgcaccaggt ttaccaccgg accaaacacc tcttcacgag ttaagcgcaa tttagcatcg
    16441 ggatttacca ccagcgttgg cgcaacataa tacccctctc cggctggtcc attcgacccg
    16501 cgaatcagct ctgcttgctg tgcctgcgca tcgtcgagga atgaacacac tttgtcgcag
    16561 tgcgcacgag aaaccaaagg gttaatctgt gcaacaggtg acatccccgg tcccacttgc
    16621 aacgatttta ccgcctgctc aaatccacta accagcgtgt caaacaacgg cgcttcaata
    16681 taaattcgcg aactggcggc gcatacttgc ccttgattca ggaagcttcc ggtcatcaag
    16741 ccttcaataa cccattgcgg atcagcatct tttaatacaa ttgccgggtt tttaccgccc
    16801 agttccagcg ttacacgcgt taagtgatca gcagcagttc tggcaatacc ttttcccgtc
    16861 gcggttgaac cggtaaaact gattttcgca ccatgaggat gtgacgtcag ggccgcgccg
    16921 catacagcac ctgacccggt gacgacatta aaaacgccat cagggatacc agcctcgctg
    16981 gccagttccg ccacgcgcaa catcgtcagt ggcgtggttt ccgaaggctt aatcacgatt
    17041 gaacagcctg ctgccagtgc tggcatcacc ttccacatac caatcatcaa cggaaagttc
    17101 catggcacaa ttcccgccac tacgccaacc ggctctttac gcgtccaggc ctgataacgc
    17161 gccccctggg gtaagggaat cgacaagtcc agcgttttac ccacgatttt ggtcgttaac
    17221 ccggcggtat aacgcatcca gttcagcgta cagcccactt caaaagcacg ggaaatggca
    17281 attgacttgc cttgctccag ggtttccagt tgcgccagct cctcactgtg ctgctccacc
    17341 agatcagcaa aacgtagcag aatacgttca cgctctgcgg gtaatcgccc ggcccagcga
    17401 cgcgagacaa aggcccgcca ggcagacatg actgcgttat ctacatccgc ttcgttggca
    17461 tcagcagtag acgcaatttc ttgcccggtg gccggatcaa agatcgccaa ccgtttttca
    17521 ctttgtgcgg ggccaggacg accatcaata taaagaccgt gttgacgatc gagaaactgt
    17581 tggacctggc ttaatactgc tacatgcggc tctgtcatca cttttcctta ttatttaccc
    17641 agtgtgattt cagtgtacgc agcgacaaga aaagtcactt ttttcgctgt gacattcgct
    17701 ttgtcagctg tgacaagctc cgcaaatcgt gacaataacc gcttatgtct ctatgcctga
    17761 caagacttat ttcctatagt caggctcatt agcttcgttt attgcaacac aaatgcaaca
    17821 ataaaaatac atttcacaga gcgaaaacgt gccatgaacc ccgcagtgga taatgagttt
    17881 cagcaatggc tttcccaaat caatcaggta tgcggaaatt ttaccggacg cctgctgact
    17941 gagcgttaca cgggtgtact ggacacgcat tttgccaaag gactaaagct gagtaccgtg
    18001 acaaccagcg gggtgaattt atcccgcacc tggcaggaag taaaaggcag cgacgatgcc
    18061 tggttttaca ccgtttttca gcttagtggt caggcaataa tggagcagga tgagcgtcag
    18121 gtgcagattg gcgctggcga tattacgtta ctcgatgcct cacgcccctg ttcgctttac
    18181 tggcaggagt cttctaaaca gatttcatta cttttgccac gcactctgct ggaacaatat
    18241 tttccccatc aaaaacctgt ctgcgcagaa agactggacg ctgacttacc catggtgcaa
    18301 ctcagtcatc gcctgttaca ggagagcatg aataatccgg cactttctga aacagaaagt
    18361 gaagctgcgc tacaggcgat ggtgtgtctg ctgcgcccgg tacttcatca gcgggaatct
    18421 gttcaacctc gtcgtgaacg tcagtttcaa aaagtggtta cgttgataga cgataatatt
    18481 cgcgaagaga tattacgccc ggagtggata gccggagaga caggtatgtc agtacgtagt
    18541 ttgtaccgaa tgtttgccga taaaggtttg gtagtcgcgc aatatattcg taaccgtcgt
    18601 ctcgattttt gtgcagatgc gattcgccat gccgcagatg atgaaaaact ggcaggcatc
    18661 ggctttcatt ggggattttc tgaccagagt catttttcaa cggtatttaa gcaacgcttt
    18721 gggatgacgc caggcgagta tcgacgtaaa ttccgctaac taattggcgt tgcatgtact
    18781 gcaacgccaa ttagttaaaa cagatatttg actatgcatt tttcagggca aaaggcaatt
    18841 tgacaggagt ttttgaatat tcaccttgtt tcaggaaaat agatcaatcg ccttctcctg
    18901 tagcgttatc ccgatattgc ggttttgcta ttaaaatttt cgcacccatt taccgtttat
    18961 cccttgtaca tattcccccg gtttggcccg agctacgagc ttttgcccgg cgagtttcgc
    19021 gatatcatct accgacacat tattttgctt tgccagttgt tggtaactcg ctttacgttc
    19081 ggcattaatg tcggctacta atttctctgt ttcagcatcc gttttcagcg caaccagata
    19141 accgtaaaat gtttcaccta cccgcccctg agttctggct tcatccagag tcaatgccat
    19201 tacattgctg cttaccagcc caacaagaaa cgcacaaaga agtaatgttt tcttcatcat
    19261 cacctcagaa aagatcgcta cgagtttcaa gcagctcttc gacatctttg tctgccttga
    19321 tgatgatctc atgctcaatt ttaacgttca tattgatagt gatcggttcc ttaggtgcag
    19381 cgacttcaat gcgaggcgta cagccaacca gcataaaaga tgacgtcaac gcagccagta
    19441 aaattttcat tgtttttcct cacactcttt tccttgcgga cagtcatttc ccggcagacg
    19501 tgcgttctgc tccagccatg cctggagatt atcgccaaag cgtaaactgc gccacagcgt
    19561 aaaaatattc tcttcatgat ggtaattaag gtttaccgta ccgcttttac catcaacgcg
    19621 actggtacct gtaatgttgg cctgcatggt taataaaccg agattatcta aattaatttt
    19681 tgtcgatgaa cggctaattt ccatatagcg caaccagtta attgctgaac ccgcagtcat
    19741 attgtctttt accaccgcat ccgcagtgtc tttatccagt cgcaatgtca tcggcccgct
    19801 attcgccagc cagccatctt tcacaatcca tttttcattg ttcagccata acggcagtgc
    19861 accactaaat gccccggaca tggcgaattg tttcggattg acggcgctaa ccagttcgct
    19921 ggatgagaga ttattcagcc gcaacagcgc cgggtcatgt tgcggcatac gtaattgttt
    19981 catcagtacg ttaccgccta acacatcgac gctaacatca gtcaacagca agggttcttc
    20041 ttcagtccac ggataacgcc cttgcaaatc agccgtaata tttttcgctg tcaccagatt
    20101 aatcacttcg gcaattcgca acgtaacggg gccgcgagtc cccagatgcc aggctccatc
    20161 ggcaaaacgg aaaggcagga caaaatcgac accgttaacc tgattatctg gcatccaggc
    20221 actaccgcct ttcaacacgc cgtgtcctcc cgcgcggaat ccttgttcag gcgcagcaga
    20281 aaatgcaacc tgagcataca gttcaccatc gcgtaagttc atcttccagt cgggtggcac
    20341 cagcggctgg aatacggtca gtgattgttt aggccaccag gcgttaccgc gcagacgaat
    20401 accgtcccag cgaccattta cccgaaccgg gccaatctca ccagcatgta aatcgccttt
    20461 aaagaggaaa taggtaggat cgcgcccatc gacgctaaat tttaaggttg atggcggtaa
    20521 cacactgccg ccagtgaaca gcgtttgccc ggcgtccagt gacagcgcgc cgctaaagga
    20581 gggatgctgt gcgtcacgta cccagacgat gggcttgtcg agaattaatc gcggcttttc
    20641 taccgtcatc gtaccgtatt gtaactggtc gaaaccggtg gagagatcgg tcagcgtaat
    20701 cgtgctgtca tgccactcac cttttcctgc gacatcccag gtggcattca tcggtgtaaa
    20761 actccctttt ccccagtagc gccactgcca gcggccagcg tcagggagaa aatcattcgc
    20821 cagcccatcc atatgcagca cgaaatcgcc cagttcattt tcatgcgcct gcaagatggc
    20881 ctgcaaacgt ccgtcaacac cacgttgggt gacttttaca cccgctaaag gccagcggat
    20941 ttcatcgatg tccagcgaat cgatgactct tccctttgaa cgaagtaacg cgcctggctc
    21001 aaaggtcagc gttgggtcag acagacttcc acttagctgc gcaggtaaac gggcatataa
    21061 aatgaggtcc gcctgtttcg cttcaccggt cagctgcaga ggcagctgac tgttatccat
    21121 gcttaatttt cctgggccaa aattaagcac cgcgttgccc ttacccgctt gcccctgggt
    21181 cagcacactc agtcgtccgc tgaccagagc gttctcaagc cctgcctgcc agttgtcgac
    21241 tttgacaccc agtcggccac tcaaaggaaa acctgcatac ggccagctcc agcgaccatc
    21301 gcttacggtc aattgttgac gagtaatttg ccacggcaaa tcgagcaacg gatcgccgtt
    21361 atcccgtgcc agcacgatca attgcccgct attttcctgc cagtccagct cggcatccac
    21421 cagtgacggt tcctgcggca agtttaacgt cgcagtagca tgcccactta caggaagtcc
    21481 atccggcacg agcggcatag caaattcccc caccagtttt accggcggct gattttcaaa
    21541 cgcgacgaca tccagttcgc tgactgtaag ttgttgccct ttcagctggc cttgaaattt
    21601 aactttttcg ccctgataac gcagttgctg gatatcagag gttaatgcga gagagagttt
    21661 tccctgccat tcctgccagg gagaaaaaat cagtttatcg atattgatcc aggtgttagg
    21721 cagcatggcc tgccactgcg cgagtgtttt tggagcggct ggcgattgct ccgtctgcgg
    21781 caatttcgcc agacaagcag aatcaagttc taccgtgccg acgttcaata accagcggct
    21841 gggatgtgaa aggctggcgt tggtgatatg cgcaagctga caatctccca ccagataacg
    21901 gagatcggga atgattaaac ctttacgcgt aatgcgtggg ctttcatcta atgcaatacg
    21961 tgtcccgagc ggtagccaga tgcccgccag cgtgggaacc cacagcccga gcgtcatcag
    22021 cagcgtcaac ggcacaagaa taatcagtaa taacagcgcg agaacggctt tatatttacc
    22081 cagcatgggt agttaatatc ctgatttagc gaaaaattaa gcattcaata cgggtattgt
    22141 ggcatgttta accgttcagt tgaaggttgc gcctacacta agcatagttg ttgatgaatt
    22201 tttcaatatc gccatagctt tcaattaaat ttgaaatttt gtaaaatatt tttagtagct
    22261 taaatgtgat tcaacatcac tggagaaagt cttatgaaac tcgccgttta tagcacaaaa
    22321 cagtacgaca agaagtacct gcaacaggtg aacgagtcct ttggctttga gctggaattt
    22381 tttgactttc tgctgacgga aaaaaccgct aaaactgcca atggctgcga agcggtatgt
    22441 attttcgtaa acgatgacgg cagccgcccg gtgctggaag agctgaaaaa gcacggcgtt
    22501 aaatatatcg ccctgcgctg tgccggtttc aataacgtcg accttgacgc ggcaaaagaa
    22561 ctggggctga aagtagtccg tgttccagcc tatgatccag aggccgttgc tgaacacgcc
    22621 atcggtatga tgatgacgct gaaccgccgt attcaccgcg cgtatcagcg tacccgtgat
    22681 gctaacttct ctctggaagg tctgaccggc tttactatgt atggcaaaac ggcaggcgtt
    22741 atcggtaccg gtaaaatcgg tgtggcgatg ctgcgcattc tgaaaggttt tggtatgcgt
    22801 ctgctggcgt tcgatccgta tccaagtgca gcggcgctgg aactcggtgt ggagtatgtc
    22861 gatctgccaa ccctgttctc tgaatcagac gttatctctc tgcactgccc gctgacaccg
    22921 gaaaactatc atctgttgaa cgaagccgcc ttcgaacaga tgaaaaatgg cgtgatgatc
    22981 gtcaatacca gtcgcggtgc attgattgat tctcaggcag caattgaagc gctgaaaaat
    23041 cagaaaattg gttcgttggg tatggacgtg tatgagaacg aacgcgatct attctttgaa
    23101 gataaatcca acgacgtgat ccaggatgac gtattccgtc gcctgtctgc ctgccacaac
    23161 gtgctgttta ccgggcacca ggcattcctg acagcagaag ctctgaccag tatttctcag
    23221 actacgctgc aaaacttaag caatctggaa aaaggcgaaa cctgcccgaa cgaactggtt
    23281 taatcttgcc gctcccctgc attccagggg agctgattca gataatcccc aatgaccttt
    23341 catcctctat tcttaaaata gtcctgagtc agaaactgta attgagaacc acaatgaaga
    23401 aagtagccgc gtttgttgcg ctaagcctgc tgatggcggg atgtgtaagt aatgacaaaa
    23461 ttgctgttac gccagaacag ctacagcatc atcgctttgt gctggaaagc gtaaacggta
    23521 agcccgtgac cagcgataaa aatccgccag aaatcagctt tggtgaaaaa atgatgattt
    23581 ccggcagcat gtgtaaccgc tttagcggtg aaggcaaact gtctaatggt gaactgacag
    23641 ccaaagggct ggcaatgacc cgtatgatgt gcgctaaccc gcagcttaat gaactcgata
    23701 acaccattag cgaaatgctg aaagaaggtg cacaagtgga tctgaccgcg aaccagttaa
    23761 cgctggcgac cgcaaaacag acattaactt ataagctggc ggatttaatg aattaatagc
    23821 tgccacagct cccggcggca agtgactgtt cgctacagcg tttgccgttg ggtaatgcac
    23881 acatcccaat cgccgtacca tccagttgac gggcaacaga aagcgaaccg ccgatcattg
    23941 cacaatttgc ttctccacta ctggacatcg acgcttttaa acctggcgct acgtgcgcgg
    24001 cagtcgcctg ctgaacaggt tcactactac acgccgacaa caataaagcg gcacacccta
    24061 cccaaaacgc tgctcgcatc ttttcttcct ctgatcttca agccaaacga caccgccata
    24121 aataataggc agcacagagg gcggcgtcga gagctgtcct gcgcgttgcc ccgcattttt
    24181 acttttttat ggctattttt ttgccctctg tttgatcaaa acattcatta cgctgatgtg
    24241 ggggacacaa aagcgaaaat gcagaagaaa gccatttgct aaaattgaaa gattactact
    24301 gggcgcgcag caatttcgtg cgcccctcat ttgcgcaatg taagggtgtc atatgattac
    24361 tattgacggt aatggcgcgg ttgcttcggt cgcatttcgc accagtgaag ttatcgccat
    24421 ctaccctatt acccccagtt ccacgatggc agaacaggct gatgcctggg ccggaaacgg
    24481 cttaaagaac gtttggggag acacaccacg cgtggttgaa atgcagtcgg aagcgggtgc
    24541 tatcgctacc gtgcatggcg ctttgcagac gggtgccctt tcaacatcgt ttacgtcatc
    24601 gcagggtttg ctgctgatga tcccgacgct gtacaaactg gcaggcgaac taacaccgtt
    24661 tgtcctgcat gtagcggcac gtaccgttgc cacacatgca ctctctattt ttggcgatca
    24721 ttccgacgtt atggcggtgc gccagacggg ttgcgcgatg ttgtgtgcag caaacgtcca
    24781 ggaagcgcaa gactttgctc tcatttcgca aatcgcgacg ctgaaaagcc gcgtgccatt
    24841 tattcatttc tttgatggtt tccgcacgtc ccacgaaatc aataaaatta tcccgctggc
    24901 cgatgacacg attcttgatc tcatgccgca ggtcgaaatt gatgctcatc gcgcccgggc
    24961 actcaacccg gaacatccgg tgatccgcgg tacgtccgcc aatcctgaca cttatttcca
    25021 gtctcgcgaa gccaccaacc catggtacaa cgcggtctat gaccatgttg aacaggcgat
    25081 gaatgatttc tctgccgcga caggtcgtca gtatcagccg tttgaatatt acgggcatcc
    25141 gcaagcggaa cgggtgatta tcctgatggg ctctgccatt ggcacctgtg aagaagtggt
    25201 tgatgaattg ctaacccgtg gcgaaaaagt tggcgtgctg aaagttcgcc tgtaccgccc
    25261 cttctccgct aaacatttac tgcaagctct gccgggatcc gtacgcagcg tggcggtact
    25321 ggacagaacc aaagaacccg gtgcccaggc agaaccgctc tatctggatg taatgaccgc
    25381 actggcagaa gcctttaata atggcgagcg cgaaactctg ccccgtgtca ttggtgggcg
    25441 ctatggtctt tcatccaaag aatttggccc agactgtgta ctggcggtat ttgccgagct
    25501 caacgcggct aaaccgaaag cgcgctttac ggttggtatt tacgatgatg tgaccaatct
    25561 gtcactgccg ttgccggaaa acaccctgcc aaactcggcg aaactggaag ccttgtttta
    25621 tggccttggt agtgatggca gcgtttccgc gaccaaaaac aatatcaaga ttatcggtaa
    25681 ttccacgccg tggtacgcac agggctattt tgtttacgac tccaaaaagg cgggcggcct
    25741 gacggtttct caccttcgag tgagcgaaca gccgattcgt tccgcttatc tcatttccca
    25801 ggctgatttt gttggctgcc accagttgca gtttatcgat aaatatcaga tggctgagcg
    25861 tttaaaacct ggcggcattt tcctgctcaa cacgccgtac agcgcagatg aagtgtggtc
    25921 gcgcttgccg caagaagttc aggccgtgtt aaaccagaaa aaagcgcgct tctatgtgat
    25981 taacgcggcg aaaatcgccc gcgaatgtgg cctggcggcc cgtattaata ccgtcatgca
    26041 gatggctttt ttccatctga cgcaaattct gcctggcgat agcgccctcg cagaattgca
    26101 gggtgcgatt gccaaaagtt acagtagcaa aggccaggat ctggtggaac gcaactggca
    26161 ggctctggcg ctggcgcgtg aatccgtaga agaagttccg ttgcaaccgg taaatccgca
    26221 cagcgccaat cgaccgccag tggtttccga tgccgcccct gatttcgtga aaaccgtaac
    26281 cgctgcgatg ctcgccgggc ttggtgacgc cctccccgtt tcggcgctgc cgccagacgg
    26341 cacctggccg atgggcacta cgcgctggga aaaacgcaat atcgccgaag agatccccat
    26401 ctggaaagag gaactctgta cccaatgtaa ccactgcgtt gccgcttgcc cacactcagc
    26461 tattcgcgca aaagtggtgc cgcctgaagc gatggaaaac gcccctgcca gcctgcattc
    26521 gctggatgtg aaatcgcgtg atatgcgcgg gcagaaatat gtcttgcagg tggcaccgga
    26581 agattgcacc ggttgtaacc tgtgcgtcga agtttgcccg gcgaaagacc gtcagaatcc
    26641 agagattaaa gccatcaata tgatgtctcg cctggaacat gtcgaagaag agaaaatcaa
    26701 ttacgatttc ttcctcaacc tgccagaaat cgaccgtagc aaactggaac gtattgatat
    26761 tcgtacatcg cagctgatta caccgctgtt tgaatattca ggtgcttgct ccggttgtgg
    26821 cgagacgccg tatattaaat tactgactca gctctatggc gaccggatgt tgatcgctaa
    26881 cgccactggc tgttcttcaa tttatggcgg taacctgccc tctacaccgt ataccaccga
    26941 tgccaacggt cgtgggccgg catgggcgaa ctctctattt gaagataatg ccgaatttgg
    27001 ccttggtttc cgcctgacgg tcgatcaaca ccgtgtccgc gtgctgcgtc tgctggatca
    27061 atttgccgat aaaatcccgg cggaattact gacggcgttg aaatcagacg ccacgccaga
    27121 ggttcgtcgt gaacaggttg cagctttacg ccagcaactc aacgatgttg ccgaagcaca
    27181 tgaactgcta cgtgatgcag atgcactggt ggaaaaatca atctggctga ttggtggtga
    27241 tggctgggct tacgatatcg gctttggcgg tctggatcat gtattgagtt tgacggaaaa
    27301 cgtcaacatt ctggtgctgg atacgcaatg ctattccaac accggtggtc aggcgtcgaa
    27361 agcgacaccg ctgggtgcag taactaaatt tggcgagcac ggcaaacgta aagcgcgtaa
    27421 agatcttggc gtcagtatga tgatgtacgg tcatgtttat gtggcgcaga tttctctcgg
    27481 cgcgcagctg aaccagacgg tgaaagcgat tcaggaagcg gaagcgtatc cggggccatc
    27541 gctgatcatt gcttatagcc cgtgtgaaga gcatggttac gatctggcac tcagccacga
    27601 ccagatgcgc caactcacag ctaccggctt ctggccgcta tatcgctttg atccgcgtcg
    27661 tgccgatgaa ggcaaactgc cgctggcctt ggattcacgc ccgccgtcag aagcactgga
    27721 agaaacgtta cttcacgagc aacgtttccg tcggctgaat tcgcagcagc cagaagtggc
    27781 agaacagtta tggaaagatg ctgcagctga tttgcaaaaa cgctatgact tcctggcaca
    27841 aatggccgga aaagcggaaa aaagcaacac cgattaaatg ctctggataa ggattatcca
    27901 attctaaaaa aaaagcccgg acgactgttc gggcttgtct ttttatatgt tggaaaatca
    27961 gtggcaatgc aatggcccaa cagaaaataa aatctgtgac aataaaggca tataacccgc
    28021 gcagaataac gtatagcaaa ttaaaagtat aatttttatt ttgtatgtat tatcttcgat
    28081 acattcacca gacttattat catttcagag gaattatttg attaaggttt tacttaaggc
    28141 gtaacaaatg atatttatcg gctaactgaa cttctccttt aggatgtttt cactccccga
    28201 aatggggata aaaggcaaat aaaataacta aaggatttat tcaatgaaaa gcaaagtact
    28261 ggcactttta attcctgccc tgctcgccgc aggtgctgca catgcagccg aagtttataa
    28321 taaagacggc aacaaattag atctgtatgg caaagttgat ggcctgcatt atttttctga
    28381 taattcagcg aaagatggcg accagagcta tgcgcgtctg ggttttaaag gcgaaaccca
    28441 aattaacgat caactcactg gctacggtca atgggaatac aatattcagg caaacaacac
    28501 tgaatcttca aaaaaccagt catggacccg tctggcattt gccgggctga aatttgcaga
    28561 ttacggttct ttcgattacg gacgtaatta tggcgtaatg tacgacatcg aaggctggac
    28621 cgatatgctg cctgaatttg gcggtgactc ttataccaat gcagacaact ttatgactgg
    28681 tcgagccaat ggcgtcgcga cttatcgtaa tactgatttc ttcggtctgg taaatggtct
    28741 gaacttcgcg gtgcagtatc aaggtaacaa cgaaggagcc agtaatggtc aggaaggcac
    28801 caacaacgga cgtgatgttc gccatgaaaa cggtgacggc tggggtcttt ccacaacata
    28861 tgatttaggc atgggcttta gcgctggtgc ggcatacacc tcttctgacc gcaccaatga
    28921 ccaggttaac catactgcgg cgggtggtga taaagcagac gcgtggactg ctgggctaaa
    28981 atacgatgct aacaatattt acctggcaac catgtattca gaaacgcgta atatgacccc
    29041 gtttggcgac agcgattatg ctgtggcaaa caaaacccag aattttgaag tcactgcaca
    29101 gtaccagttt gattttggtc tgcgtccggc agtctctttc ctgatgtcta aaggccgtga
    29161 cctgcacgct gcgggtggtg cagacaaccc ggcaggtgtt gatgataaag atctggttaa
    29221 atacgccgat attggcgcga cttactattt caataaaaac atgtccacct acgttgacta
    29281 taaaatcaac ctgttggatg aagatgacag cttctacgct gccaatggca tctctaccga
    29341 tgatattgtc gctttaggtc tggtttatca gttctaaatc ctcctgcccg ctgttatggc
    29401 gggctttttc tgcttattct tcctcctttg atctaaatta aaaatgtgaa ctccgtcatt
    29461 acacaaaaag tgtcatctgg cgttacactt tatgcggata ctaaaacagg aggttttatg
    29521 aacagaacga ttcttgtccc tatcgatatt tccgattcag aattaactca acgcgtgatt
    29581 agccacgttg aggaagaggc aaagattgat gatgcagagg ttcatttcct gacggtaata
    29641 ccttcactgc cctactatgc ctctctgggt ttagcgtatt ccgcagaatt accggcaatg
    29701 gatgacctga aagcggaagc caaatcgcaa ctggaagaga tcattaaaaa atttaaactg
    29761 ccaaccgaca gagtgcatgt ccatgttgag gaaggctcgc ccaaagaccg cattctggaa
    29821 ttggcgaaga agatccccgc tcatatgatc atcattgctt cccatcgacc ggatatcacc
    29881 acttatctgc tcggttccaa cgccgcagct gtagtgcgtc acgcagagtg ctccgtgctg
    29941 gttgtgcgct gacactaacg cccgcacatt gctgcgggct ttttgattca tttcgcaaat
    30001 gtgctgacat tttcccctct aatccgtacc atacacgcca cagtttttta tatcagattt
    30061 cttatgctgg gcgttccggc atgacgcata ctcttctgat gccatataac gaattgagtc
    30121 gcttttaaat gtcgcaaaat caagaaatta gtaagaaaga acaatacaac ctgaacaaat
    30181 tacaaaaacg tctgcgtcgt aacgtgggcg aagccattgc tgacttcaat atgattgaag
    30241 aaggcgatcg catcatggtt tgcctctccg ggggtaaaga cagctatacc atgctggaga
    30301 ttctgcgcaa tttgcagcaa agcgcgccaa tcaatttttc gctggtggct gttaacctcg
    30361 atcaaaagca accgggcttc ccggaacacg ttctgcccga gtatcttgaa aagctgggcg
    30421 ttgagtacaa gattgttgaa gagaatactt acggtatcgt gaaagagaag attccagagg
    30481 gcaaaaccac ttgctcactg tgttctcgcc ttcgtcgcgg tatcctttat cgtaccgcaa
    30541 cggaactggg ggcgacgaag atcgcgttgg gtcaccatcg tgacgatatc ctgcaaacgt
    30601 tgttcttaaa tatgttctac ggcggtaaga tgaaaggtat gcctccgaaa ctgatgagcg
    30661 atgatggcaa acatatcgtt attcgtccgc tggcctactg ccgcgagaaa gatattcagc
    30721 gatttgccga tgcaaaagcg ttcccgatta ttccgtgcaa cctgtgcggt tcacagccta
    30781 acctgcaacg tcaggtgatt gctgacatgt tgcgtgactg ggataaacgt tatccagggc
    30841 gtatcgagac gatgttcagc gcgatgcaga atgtggtgcc gtcgcatctg tgcgatacca
    30901 acctgttcga tttcaaaggc atcacccacg gttctgaagt ggttaacggg ggtgatctgg
    30961 cgtttgatcg cgaagagatc ccactacaac cggcgtgctg gcagccagaa gaagatgaaa
    31021 atcagttgga tgagttacgg ctgaatgtgg ttgaagtgaa ataaccagga tagcgcccga
    31081 tgcgcaagcg tatcgggcta ctcttatgga ggccggataa gacgcggcca gcgtcgcatc
    31141 cggcaatccc gaataagatg tttactcttg cacccggcaa ttcaacattt cattatttta
    31201 ataaccgcac ccggcacgtt tttcctttaa tcttcccgcc ctgtaactgt ttccatgctt
    31261 tatgagcaac agcctgacgg accgcgacat agacatgcgc cggatgcacg gcgattttgc
    31321 caatatctgc gccatcaagc ccgatatctc ctgtcagtgc acctaataca tcacccgggc
    31381 gcattttggc ttttttcccg ccatcgatac acaacgttgc catttctgct tccagcgtcg
    31441 caatggaact attagctggc ggcgtttgcc agttaagttt tatctgcaac atgtcagaaa
    31501 tgatattggc ccgctgtgct tcttccggag cacagaaact gatcgccaga ccgctatttc
    31561 ctgcacgagc tgtacgaccg atgcgatgta catgaacttc agggtcccac gccagctcaa
    31621 agttcaccac cagctcaagc gatttaatat ccagaccacg cgcagcaaca tcagtcgcga
    31681 ccagtacacg ggcgctaccg ttagcaaaac gtaccagggt ctgatcgcga tcgcgttgct
    31741 ccaaatcgcc gtgtaatgac aatgcacttt gccctacttc attcagcgcg tcgcagacag
    31801 cctggcaatc ttttttggta ttgcaaaaca ccacgcaaga ggatggctga tgcaagctta
    31861 ataaccgttg caacagagga attttgcctt tgctggatgt ctcataaaat tgttgttcaa
    31921 tgggtggcaa agcatctgtt gagtcaattt caatcgccaa aggatcgcgt tgcactcgtc
    31981 cgctgattgc agcgatggct tccggccagg ttgccgaaaa cagaagcgtc tgtcgagatg
    32041 caggcgcaaa acggatgaca tcatcaatgg catcgctaaa tcccatatcc agcatgcggt
    32101 cggcctcatc catcaccagc gtattcaacg catccagtga taccgtgcct ttttgcaggt
    32161 gatccagcaa acgccccggc gttgccacga taatatgcgg cgcatgttgc aacgaatcac
    32221 gctgcatacc gaacggttga ccaccgcaca acgtcaaaat tttggtattt ggcagaaaac
    32281 gcgccagccg acgcaattca cctgccacct gatccgccag ttcacgcgta ggacacagca
    32341 ctaaagcctg ggtttgaaat agcgacgcat caatttgctg taacaagccg aggccaaaag
    32401 ccgccgtttt gccgctgccg gttttcgcct gcacgcgaac atcttttccg gcaagaatcg
    32461 ccggaagcgc ggcggcctgc accggcgtca tggttaaata acccaactca ttaaggttcg
    32521 tgagttgggc gggaggcaaa acattcaggg tagaaaaagc ggtcacaatc tattctcgtg
    32581 gtcatcgacg caaagttagc aggcgcgtat cctcgcagat ctacgctcac gatgcgacaa
    32641 tttaatcggt tcttcatcgg gtggtgggtc aggcatgggt tgcgggcgag ggatcggatc
    32701 gggcactgga acaggatcgc caggaatcgg ttcagggaca ggaatttgca aataaataag
    32761 tgtcgtcata tttccctctg gtcattgggt ggactcttaa agggtagacg ctgataaata
    32821 acaggcaaaa aaaagccgac tcatcaaagt cggcgtcgta cgaatcaatt gtgctatgca
    32881 gtaattcaaa aaaggaagta agacaatatg gagcgcaacg cccatcgctt gacgttgcat
    32941 tcacctgcaa gagagatatt gccctgaatg ggtagagagt ttattgactt cgctcaaact
    33001 ttgcggcgtt tttgtataca gacagccgga aaaattgctt ttgttacaac catttactac
    33061 gatgcaacca taaagcaaca ccaccaataa gaacaactaa cagaatacaa aaaattgaaa
    33121 atccgaattg ccacccgccg ccagggatcc caccaaggtt gacgccaaat aacccggtca
    33181 gaaaggtact gggtaaaaag accattgcca tcaacgacat tgtataggta cgacgagcta
    33241 aattttcctg catcacctga gcgatttcat ccgccatcac gccagtccgt gctatacagg
    33301 cgtcgatttc gtcaaggccg cgcccaaggc gatcggcaat atcctgcatc cgacggcgtt
    33361 ggtcatcgct catccacggc aaacgttcac tggcaagacg agcataaaca tcacgttgcg
    33421 gtgccatata gcgacgcatc acaattaatt gtttgcgcag cagagccagg aatccacgcg
    33481 gtggaatttg ctgatcaagg agattatctt caaggtcgat aattttatcg tgcagctgct
    33541 cgataaattc actggaatga tcggtcaacg catcgcacac atccaccagc catcccccgc
    33601 aatcggtcgg acccgtgccc tcttccagat cgctcaccac atcgtccagc gccagcactt
    33661 tgcgttgtcg ggtcgaaaca attaaccgcc cgtccatata tacacgcatg gcgaccagtt
    33721 gatcggggcg ttcatcggtg ctgccattta tacagcgcaa tgtaatcagc gtgccttcac
    33781 cgagacggct gactcgggga cgcgtgctct cgcccgccag cgcatcacgt acgttattgg
    33841 gaagcagcgg tgttgtcgcc agccattggg cgctatcatg gtgtacataa ttaaggtgga
    33901 gccaacaggg atgcgcttca tcaatcacat ctgtattttc cagcggttta acgccgcctc
    33961 taccatccag catccaggca aatactgcat ccgggacatt aacgtccgat cccttaatcg
    34021 cttccacagt gcctccatca tcaacgcatt attttgtagt ctagccttct ggccctgtta
    34081 cgcaacatct catcacccca ttaccctgaa atgattaata aaattctgtc taaattgaat
    34141 acaaaaagca aaatgctttt ccgtatacaa accgtgtgaa gtgttaaata gcgtctatca
    34201 ttatcagaat tatctgatca tatgacgtgg cttttttgcg atcggatagc aacaaaaatt
    34261 gataaaaata acgggatctc aatgattacg cacaacttca ataccctgga cttactcacc
    34321 agtcctgtct ggatcgtttc gccctttgag gaacagttaa tttatgccaa tagcgcggcg
    34381 aaactgttga tgcaagacct cacgtttagt cagctacgaa ccggacccta ttccgtctcc
    34441 tcacaaaaag aactgccgaa atacctctcc gatctgcaaa accaacacga tattatcgaa
    34501 atcctcactg ttcagcgtaa agaagaggaa acagcattga gctgtcggct tgttttgcga
    34561 aagctgacag aaacagaacc ggtgattatt ttcgaaggta tcgaagcgcc ggcaacgctg
    34621 ggtttaaaag ccagtcgctc ggcaaattat cagcgcaaaa aacaaggttt ttatgcgcgc
    34681 ttttttctga ctaactctgc accaatgttg ttgattgacc cgtcacgaga tggacaaatc
    34741 gtcgatgcta acctcgccgc gctcaatttc tatggttata accatgaaac gatgtgccag
    34801 aaacatacct gggaaataaa tatgctcggg cgtcgcgtca tgcctatcat gcatgaaatc
    34861 tcgcatttac ccggtggtca taaacctttg aattttgttc ataaactggc ggatggttcg
    34921 actcgtcatg tgcagaccta tgccggaccg attgaaattt atggcgacaa gctcatgtta
    34981 tgtattgtgc atgatattac tgagcaaaaa cggctggagg agcagctgga acatgctgct
    35041 caccatgacg cgatgaccgg attactgaat cggcgacagt tttatcacat tacggaacca
    35101 ggccaaatgc agcatctcgc catcgctcag gattacagct tgttgctcat cgacaccgat
    35161 cgttttaaac acattaacga tctctatggg cattctaaag gtgatgaggt gttatgcgcc
    35221 ctcgcccgca ccctcgaaag ttgcgctcgc aaaggcgatt tggtgtttcg ttggggaggc
    35281 gaagagtttg tcttattgct accaagaacc ccactggata ccgcgctttc gctggctgaa
    35341 actatccgcg taagcgtggc aaaagtgagt atttcgggct taccacgctt taccgtcagc
    35401 attggtgtgg cgcatcacga aggaaatgaa agcatcgatg aactgtttaa acgcgttgat
    35461 gatgctttgt atcgggcgaa aaatgatgga cgcaaccgcg tgctggcggc ataagccgcg
    35521 gatgcatctc gagatcaacg actgcgctta gcgtggcgct cccagttttc ttgcttcgcc
    35581 tgcgccgttt tacgtagtgc gacgtaacac gccccgctgc cgccatgatg cggtagcgcg
    35641 gtgcaatatg cctgaacatc atcaaattcg gtcagccagc gcgccacata gctgcggaca
    35701 atattggcat gcgatttatc atcccgccct ttaccatgaa taatcagcac gttacgcaaa
    35761 ccatccgcca gggcttgttg aataaaactg aacaccattt tgcggcactc ttccaccggc
    35821 tggcgcaaaa gattcaggct cgcctgttgc ggatatttac cactgcgcag cttatccagc
    35881 accccatgtt gcaacccttc ccgccgaaac tccagcggct gacttagtgg gatgatgtcg
    35941 agaaatccgg tggtgaggaa attatcaagc tgcagcgtgt cgatacgctg cggcgcacgt
    36001 tggttacgcg ttggatgcca gtggacatcg gtagcacgtt tcagcggctg gacatcttcc
    36061 atggcgtcaa gaaacagcga tttgtcgtca aggttcatgt tacatcctcc cgcaattaag
    36121 agcgcgatat gataaccaga ccgggtcggt ccaacaacgt attacccaaa tttccagtaa
    36181 taagttccaa atattgccga tattttaagc aaaatactta tgcatgatta ttcattcacg
    36241 atattaataa tgtaacttat attttcgtga aatctgtcac tgaagaaaat tggcaactaa
    36301 aggttaaaac cgttataaca cagtcaccgg cgcagaggag acaatgccgg atttaagacg
    36361 cggatgcact gctgtgtgta ctgtagagtc tggcggatgt cgacagactc tattttttta
    36421 tgcagtttta actttgcaga tagccgcatt ctcgccggaa ttgcgtgatt aatgacgcgg
    36481 tcagtggtgt ctggcgacta tcacgccgct gaatcaaata ataggccgct ttcggtaaaa
    36541 tttcgctaac cggcaacatc accagcccct gtccgtgcaa gggatcgcag cccatttctt
    36601 caggcagtat gctgagaaaa tcgctttttg ccaccagact gatacaggct gagaacgtct
    36661 cgcagactac accgacctgt ggcgtttgcg cctgatcgtc aagcaattca ctcaactgtt
    36721 tgtagtagct gccgtgtggc gtcggcattg tccagctgta atccagtaac tgtttgatcg
    36781 aacgggcacc aatggcgggg tgtcccgggc ggcaaaagat cgcgaattgc ttttccagta
    36841 atttctcaaa agtaaattcg tggtcgtacg gtccctgata ataggtattg atggtgaaat
    36901 ccaattctcc ctgacgcaat tcattaatca tcgacaccag ttgcccttcc ataatgcgta
    36961 cttttacctg cggatgctgc tgatgaaaac gagatatgac agctggcatc agactgcggg
    37021 aaatactggc ccccatgccg atattaatct gccctgccag ttgcccttgt cgttggcgaa
    37081 tatcctcttg ggctgcgcgc agctcttcaa gaattagact ggcgtgctga taaaaacttt
    37141 caccggcatc agttaacgtc acgcctttac tacggcgaaa aaagagttgc gccgctaacc
    37201 cttcttctag ctcctgaata gatttactca gtgccggttg cgacatattc aacattcggc
    37261 tcgctccgcg aatgctgccc tgacgagcca cttcaacaaa agcccgaatt tgatgaattt
    37321 ttacctgaaa agccatgacg ccaccgataa ccgttattta tcagaccaaa gaaactggca
    37381 tctactttaa tgcagatgat tgtgtcaggg taatttatga acggttaaaa ctgtgaaaaa
    37441 tcagttagtg ataagtaaaa actatcgcta cgtgaaccgg gtcacacttt ttactgatga
    37501 cgggaaaggt tatggagtct ttgaatcaat ttgttaattc gcttgcccca aaattatcgc
    37561 actggcgacg tgattttcat cactatgcag agtctggctg ggtggaattc cgcactgcca
    37621 cccttgttgc ggaagaattg caccagctcg gctattcact ggcgctgggt cgcgaagtag
    37681 ttaatgaaag tagccggatg ggattacctg atgaattcac tctacaacgc gaattcgagc
    37741 gcgctcgtca acagggtgcg ctagcacaat ggattgcggc ttttgaaggt ggtttcactg
    37801 gtatcgtcgc caccctggat accggtcgcc ccggtccggt gatggctttc cgtgtcgata
    37861 tggacgcgct ggatctcagt gaagagcagg atgtcagcca tcgcccctac cgcgacggtt
    37921 ttgcgtcatg taacgccgga atgatgcatg cctgtggtca tgatggacat accgccattg
    37981 ggcttgggct ggcgcatacc cttaaacagt tcgagtccgg actacatggc gtcatcaaac
    38041 tgatttttca gcctgcagag gaaggtacgc gtggcgcgcg ggcgatggtc gatgcaggtg
    38101 tcgtagatga tgttgattat tttactgccg tgcacattgg cactggcgta cctgcgggca
    38161 ccgtggtgtg cggcagtgat aattttatgg caaccaccaa atttgacgcg cacttcaccg
    38221 gtaccgccgc tcacgcaggc gcaaaaccag aagacggtca caatgccttg ttggcggcag
    38281 cacaagccac tcttgcactg catgcaatcg ccccgcacag cgaaggagct tccagagtaa
    38341 acgtgggcgt tatgcaggca ggaagcggtc gtaacgttgt tcctgcctcg gcgttgctga
    38401 aagtggaaac acgcggggcc agcgacgtca ttaatcaata tgtttttgac cgtgcacaac
    38461 aagcgattca gggcgcagca accatgtatg gtgtcggcgt tgaaactcgt ctgatgggtg
    38521 cagctaccgc cagttctcct tcgccgcaat gggtcgcatg gttgcaaagt caggcggctc
    38581 aggtcgcggg ggtcaatcag gccattgaac gtgttgaagc gcctgcgggt tccgaagatg
    38641 ccacattaat gatggcccgc gtgcagcaac atcaagggca agcctcctac gtggtgtttg
    38701 gcacacagct ggcggcaggt catcacaacg aaaaattcga ttttgacgag caggttctcg
    38761 ctattgccgt cgaaacgctg gcgcgcaccg cgctcaattt tccctggacg cgaggtatct
    38821 gatgcaggaa atctatcgtt ttatcgacga tgcgattgaa gccgatcgcc aacgttatac
    38881 cgatattgcc gatcaaatct gggatcatcc agaaacacgt tttgaagagt tctggtcagc
    38941 ggagcatctg gcttcggcgc tggaatctgc aggcttcacc gttacccgca acgtaggcaa
    39001 tatcccaaat gcctttattg cttcgtttgg tcaaggcaaa ccggttatcg ccctgctggg
    39061 agaatatgac gccctggcag gtttaagtca gcaagcaggt tgcgcgcaac ctacatccgt
    39121 gacgcccggt gaaaatggtc acggttgcgg acacaatttg ctgggaaccg ccgcctttgc
    39181 cgctgcaata gccgtcaaga aatggctgga acaatatggg caaggcggca cggtgcgctt
    39241 ttatggttgt cctggcgaag aaggcggctc gggtaaaacg ttcatggttc gcgagggggt
    39301 atttgatgat gtggatgcgg cactcacctg gcacccggaa gcctttgccg gtatgttcaa
    39361 tacccgcacg ctggcaaaca ttcaggcatc atggcgcttt aaagggatcg cagcacatgc
    39421 cgcgaattcc cctcatttgg gacgcagcgc ccttgatgcc gtaacgttga tgaccactgg
    39481 caccaacttc ctcaacgaac atattattga aaaagcgcgc gtacactatg ccatcacaaa
    39541 tagcggcggg atctcgccca acgtggtcca ggcgcaggca gaagtgcttt atcttatccg
    39601 cgcccccgaa atgaccgacg tgcagcatat ttatgatcgg gtcgccaaaa tcgccgaagg
    39661 tgcggcattg atgaccgaaa ccacggttga atgccgcttc gacaaagcct gttccagtta
    39721 tctcccgaat cgcaccttag aaaatgccat gtaccaggcc ctatcccatt ttggtacccc
    39781 ggaatggaac tccgaagaac tggcttttgc gaaacaaatt caggctacgc tcacctccaa
    39841 cgatcggcaa aacagtctga ataatatcgc cgcaaccggt ggcgaaaacg gcaaggtttt
    39901 tgcactacgt catcgtgaaa cggtactggc gaatgaagtc gctccatatg ccgccaccga
    39961 taacgtgctt gcggcatcga ctgatgtcgg cgacgtcagt tggaaactgc ctgttgccca
    40021 gtgtttcagc ccctgttttg ccgtcggtac accgctacat acgtggcaac tggttagcca
    40081 ggggcgaaca tctattgctc ataaaggaat gctgctggcg gcgaaaacta tggcagcaac
    40141 cacagtcaat ctcttccttg attcagggct attgcaagaa tgccaacaag agcatcagca
    40201 agtaacggac acgcaaccgt atcactgccc tatcccgaaa aacgtgacac cgtcaccttt
    40261 aaaataacaa caacaacgca aacacaacaa ccgaggaatg cccatgagta tgtcatccat
    40321 accgtcgtcc tcccaatccg ggaagctcta tggctgggtc gaaagaattg gtaacaaggt
    40381 tccccatcct tttctgctct ttatctattt gattatcgta ctcatggtga cgacggcaat
    40441 tttgtcggcc tttggcgtca gtgcgaaaaa cccgaccgat ggtacgccgg tcgtggtgaa
    40501 aaacctgctc agtgtggaag gattacactg gtttttaccc aatgttatta aaaactttag
    40561 cggttttgct ccacttggtg cgatcctggc gctggtttta ggtgccggtc tggcggagcg
    40621 cgtcggctta ctgccagcac taatggttaa aatggcatcg catgttaatg cccgctacgc
    40681 cagttatatg gtgctgttta ttgctttttt cagccacatt tcttccgatg cggcgttagt
    40741 gatcatgcca ccgatgggtg cgctgatttt tctggcggtg ggcaggcatc cagttgcagg
    40801 tttactggct gccattgcag gcgtaggttg cggctttacg gctaatttac tgattgtcac
    40861 aaccgacgtg ttgctgtcgg ggatcagcac ggaagcggca gctgcgttca atccgcaaat
    40921 gcacgtcagt gtaattgata actggtattt tatggccagc tccgtagtcg tactgacgat
    40981 tgttggcggc ctgataaccg acaaaatcat cgagccacgg ttaggtcaat ggcagggaaa
    41041 cagcgatgag aaactgcaga cattgaccga aagtcagcgt tttggtttac gcatagcagg
    41101 tgtcgtatcg ctacttttta ttgctgcgat tgcgctgatg gtgatcccgc aaaacgggat
    41161 attgcgcgat ccgattaatc acaccgtgat gccatcaccc tttattaaag gtatcgtgcc
    41221 actgatcatt ctttttttct ttgttgtctc gctggcttat ggcatcgcta cccgcacaat
    41281 tcgacgtcag gcggatttac cgcatttaat gattgaaccg atgaaagaga tggcgggatt
    41341 tatcgtgatg gtttttcccc tcgcccaatt tgtcgccatg tttaactgga gcaacatggg
    41401 gaaattcatc gccgtggggc tgaccgatat actggaaagt tcagggctta gcggcatccc
    41461 ggcgtttgtc ggtctggcgt tgctttcctc tttcttatgc atgtttattg ccagcggttc
    41521 cgcaatctgg tcgattcttg cccccatttt cgtaccaatg tttatgctac ttggctttca
    41581 cccggcattt gcgcaaatcc tctttcgtat tgccgactca tccgtattgc ctttagcgcc
    41641 ggtatctcct tttgttccac tgtttcttgg attcctgcaa cgctacaaac cagacgcgaa
    41701 actgggtact tactattcgt tagtcttgcc ctatccactt atctttttgg tggtatggct
    41761 gctgatgttg ctggcgtggt atcttgtcgg tctgccgata ggtccgggta tttacccacg
    41821 tttgtcttaa gagagaacgg atgctgagat tacttgaaga aaaaattgcc acgccactgg
    41881 gtccactgtg ggtgatttgc gatgagcaat ttcgcctgcg ggcggttgaa tgggaagagt
    41941 acagcgaacg catggtgcag ctgctggaca tccattatcg caaagaaggc tatgagcgca
    42001 tttctgccac caatccaggc ggtttaagcg acaagcttcg tgaatatttt gccggtaatc
    42061 ttagcattat tgatacgctt cccactgcta cgggggggac gccatttcag cgcgaagtct
    42121 ggaaaacact acgcactatc ccctgcgggc aggtaatgca ttacggccaa ctggctgagc
    42181 aattgggccg tcctggcgcg gcgcgtgccg ttggtgcggc aaacggatcg aatcccatca
    42241 gcatcgtcgt accttgccat cgggttattg gccgaaacgg caccatgacc ggatatgcag
    42301 gcggagttca gcgaaaagag tggttattgc gccatgaagg ttatcttttg ctgtaaacat
    42361 taaacaattt gtgccagctt gttcacactt ttatgtaaag ttacccttaa caacttaagg
    42421 gttttcaaat agatagacat atatttacat ctaatatcgg aattctctgc tgttaaggtt
    42481 tgcttagact tacttgctcc ctaaaaagat gttaaaattg acaaatatca attacggctt
    42541 gagcagacct atgatcccgg aaaagcgaat tatacggcgc attcagtctg gcggttgtgc
    42601 tatccattgc caggattgca gcatcagcca gctttgcatc ccgttcacac tcaacgaaca
    42661 tgagcttgat cagcttgata atatcattga gcggaagaag cctattcaga aaggccagac
    42721 gctgtttaag gctggtgatg aacttaaatc gctttatgcc atccgctccg gtacgattaa
    42781 aagttatacc atcactgagc aaggcgacga gcaaatcact ggtttccatt tagcaggcga
    42841 cctggtggga tttgacgcca tcggcagcgg ccatcacccg agcttcgcgc aggcgctgga
    42901 aacctcgatg gtatgtgaaa tcccgttcga aacgctggac gatttgtccg gtaaaatgcc
    42961 gaatctgcgt cagcagatga tgcgtctgat gagcggtgaa atcaaaggcg atcaggacat
    43021 gatcctgctg ttgtcgaaga aaaatgccga ggaacgtctg gctgcattca tctacaacct
    43081 gtcccgtcgt tttgcccaac gcggcttctc ccctcgtgaa ttccgcctga cgatgactcg
    43141 tggcgatatc ggtaactatc tgggcctgac ggtagaaacc atcagccgtc tgctgggtcg
    43201 cttccagaaa agcggcatgc tggcagtcaa aggtaaatac atcaccatcg aaaataacga
    43261 tgcgctggcc cagcttgctg gtcatacgcg taacgttgcc tgatttttcc gcataactca
    43321 ctatccttct gtcatatcat taaatttttc tgatttattg atctggcaga aggttcatca
    43381 ctgtttcatt caccagatat gggttaatct tttaattaca aactgcgttg acagttgttg
    43441 taaggagacc ctgtatggct atgtatcaga acatgctcgt tgttatcgat cctaaccagg
    43501 acgaccaacc agcattgcgg cgagctgttt atttacatca acggattggt ggcaaaatta
    43561 aagccttttt gccgatctat gacttctcat acgaaatgac caccctgctc tcctcggacg
    43621 aacgtaccgc tatgcgtcag ggcgtcatca gccagcgtac agcctggatc cacgagcagg
    43681 caaaatatta tctcaatgct ggcgttccca ttgaaattaa agtggtctgg cataaccgtc
    43741 ctttcgaagc catcattcag gaagtgatca gcggcggaca cgatttggtg ctaaaaatgg
    43801 cgcaccaaca tgaccgtctg gaagcggtga tttttacgcc aacggactgg catctgttac
    43861 gcaaatgccc aagcccggtg tggatggtga aagaccagcc gtggccggaa ggaggcaagg
    43921 cgctggtggc ggtgaatctc gccagtgaag agccgtatca taatgcgctc aatgaaaaac
    43981 tggtcaaaga gacgatcgaa ctggcagaac aagtcaacca taccgaagtt catctggttg
    44041 gcgcttatcc ggtaacgcca attaatatcg cgattgaact gccggaattt gacccgagcg
    44101 tttataacga tgccattcgt gggcaacatt tgctggcaat gaaagccctg cggcagaaat
    44161 tcggcattaa tgaaaacatg acgcacgtag aaaaaggtct gccagaagag gtgattcctg
    44221 atttggcgga gcacttacag gcggggattg tggttctggg cacggtagga cgcaccggta
    44281 tttcagcagc attcctcggc aacacggcgg aacaggtgat tgatcatctt cgctgcgacc
    44341 tgctggtcat taaacctgac cagtatcaga cacccgttga actggatgac gaagaagacg
    44401 attaacgact cttcaataac tgacaaggcc cgagttatcg ggcctatttt ttacttactg
    44461 ctcttcgccg ccaaggaaat aaattcccaa cgggattgcc agcaacacag taaagaccag
    44521 gctataaaca aaaatcatcg atgactgaat cacatacatt gatgtcgtcc actcagacag
    44581 cggaatattg tactgttcta taacgccgcc gatggtcgcg cgagtcacaa ccgacgccgc
    44641 aataatgaaa accgccaaca aaccaaagag aaatttcttc cctttcgctg acttcagttt
    44701 cgccataatc atgatgtaat ccttgtgcag acaaatttct tgttacctaa acgtaacaat
    44761 accatgacat ttcaccgttg tctgctctga aaacctcacc tcttagctgg atttacaatc
    44821 aacgcattga ttagttagct aatgttgcta cttccttccc tgactattga tgatctgaat
    44881 gaattgtcgc ggtaaaatag ccccgccagg ggtttccggc atgacgacaa ttatctggag
    44941 gagcctgata aaacaatgat cgctgaactg tttacaaata atgcgcttaa tctggtcatt
    45001 attttcggta gctgcgcagc attgattctg atgagctttt ggtttcgccg tggaaatcgt
    45061 aaaagaaaag gatttttatt ccatgcggtg caatttttaa tctacaccat aattatcagt
    45121 gctgttggta gcattattaa ttatgttata gaaaactata aactcaaatt tatcacccca
    45181 ggcgttatcg attttatctg tacgtccctg attgcggtta ttctgacgat taagctattt
    45241 ctgctgatta atcagtttga aaaacagcag attaaaaaag gtcgcgatat caccagtgcg
    45301 cggattatgt cgcgtatcat caaaatcacc attattgtgg tgcttgttct gctttatggc
    45361 gaacatttcg gcatgagcct ttctggcttg ctgacctttg gtggtattgg tggtctggct
    45421 gtcggtatgg ccggtaaaga tattctgagt aacttctttt ccgggattat gctctatttc
    45481 gaccgtcctt tcagtattgg cgactggatc cgttcaccgg acagaaatat cgaaggtaca
    45541 gtagcggaaa ttggctggcg aattaccaaa attacgacct ttgataatcg tccattgtac
    45601 gtaccgaact cgctgttttc gtcgatcagc gtagaaaacc caggacgaat gaccaaccgc
    45661 cgcattacca cgaccattgg tttacgttat gaggatgcgg caaaagtggg cgttattgtc
    45721 gaagctgtac gtgagatgct gaaaaatcac ccggccatcg accagcgaca aaccttactg
    45781 gtttatttca accagtttgc tgactcttca ttgaatatta tggtttattg ctttaccaaa
    45841 accacggtat gggctgaatg gcttgctgca cagcaagacg tttatttgaa gattatcgat
    45901 attgtacagt cacacggcgc ggactttgcc ttccccagcc agacgctgta tatggataac
    45961 attacaccgc cggaacaggg tcgctaaatc agacatcact ggcgttatgc acaagggtaa
    46021 cgccagttcc catcacatca atgcttcaca atatacatag tccgactgta cgccacatct
    46081 tcaggattat taatgggata acctttcagc cacggcttga ttaatcgtcc attggtatat
    46141 tgataaattg gtgcaatcgg tgcttgctcc atgaggattt tttctgccgc gttgtaatcg
    46201 gcattacgcg ctttaacggt attttccgtc gatgcctggg ccagaacttt gtcatatgcc
    46261 ggattgttaa agcgtgaaat atttcctgaa tgcgttgacg ttaataatgt caggaaagtg
    46321 gagggttcat tataatcccc cacccacgag gcgcggataa catcaaaatt gccggtgtta
    46381 cggctatcga tataggtttt ccattcctga ttttgcaatt taacatctac gccaaggttc
    46441 tttttccaca tcgatgctac agcaatcgca attttttgat ggttttctga agtgttatac
    46501 aaaagcgtca gcttcagcgg tttttgcgga ccataaccag ctgcgctcaa caaagttttt
    46561 gcctgcgcat tcagttcttc ctgactcatt tgttcaaacg gcgaaggttc cggcgtaaat
    46621 cccgcggtaa catctggtgt aaaatgccac gctggctttt cgcccgtccc taatactttt
    46681 tcggtcatca ggcggcgatc tatcgtcata cttaatgcca gacgaacgcg ctgatctgcc
    46741 gtcggccctt tttgcgtgtt aaacgcataa taataggtcc cgagctgcgg cggcgtataa
    46801 acctgccccg gaatatcctt caacagcttc tgatacatat ttttcgggaa ggattcggtg
    46861 atatcaatat cccccgcgag gtaacgctta gtggctgcgg attcctgatt aattggcagg
    46921 aaggtcactt tttgcagtac cgttttggcg ttatcccaat aatgggtatt cggtaccacg
    46981 accagttttt cattgactac gcgctcttta agaacataag cgccattgcc gatcagattt
    47041 ccgggtttcg tccactcttt accgctttct acgttggctt tttgcaccgg gaagaaggca
    47101 aagttagcgg ttaaattcac aaaccacggc aacggtttat caagctgaat tttcaaagta
    47161 tgggcatcaa ctgcggtgac gccaagctgg tcaggcgtag ctttaccatc aataatcgcc
    47221 tgtgcgttgt tgattcccgc cagcgcggca aaccatgcaa atggcgacaa tgtttttggg
    47281 tccaccagac gttgccagct gtagacaaaa tcttgcgccg ttaccggtgt gccatccgcc
    47341 cattttgcgt tatcgcgcag ggtaaaagtc cagatacggt tgtcattact tttccactga
    47401 gtcgcaacgc cggggacaat ctcccctttt tcgttctgat tcaccagacc ttcaaacaga
    47461 tcgcgaatga cctgaatctc tggcaggccc acggctttag cgggatccag cgacgcaggc
    47521 tcatctttaa tgtggcgcac cagctcctgc ttctctgcca gtactgtgcc gctcggaact
    47581 tctgcagcat acgaaagaga aatgctgctg accaacagcg cacaacacgt gactgaaaca
    47641 gagtgcttca taagtttccc tctaaccgac attaaaattg atgcgtaatt atttgtttcg
    47701 ccttaaagaa atgcaaacaa cttccatcaa aaaagtgaca aaggaagcat caaatgtttt
    47761 aagtatcaat atatcaaatc agatttagtg taaataatag tctccaaaat gcggtaaagc
    47821 acatagaact ccgaacacta cgttcgggct tcgcacgttc aaacccgttt tcggtatcat
    47881 aatcagcatc tgtcgccatt gtacgaagaa taaaaaatga ccaaaacgtt gaaaggaact
    47941 gagaatacgt taagagaaga attaaattaa tgtatcagca agtagtgcta aacagcacct
    48001 ttatacttca gcctatctat aaataatgag aatgccgagc cagcatgtcg acggtgtgga
    48061 tagtacaggt gataaccggg taaatctggt gtgaatttat ccaaaacacg tatcagtttt
    48121 ttttctttaa tagcccgctc aacctgatca taaggtagat acgccaatcc atgcccatca
    48181 attgcagcat caatgatcag gtctatcgta ttcagtaaaa gctgaccttc catgcgaaca
    48241 cgaacttcac gtccaccgcg tattaatctc cagcgatttg ctgtacccga tgtgggaaga
    48301 tacaaattaa ttgcctgatg atctattaat tgtgacactg acgttggaac acttcggcga
    48361 gaaaaataat ccggtgagcc aacaatagcc attggtatat ctggcccgat tcgaatggcg
    48421 atcatatctt tatccatctc cccacccaga cggacgcctg catcaaaacg ttcagaaacg
    48481 acatcggtca aaccataatc aatggtgagc tgaatatcaa tttcaggatg cgatttcagg
    48541 aatgtgcgca ttgctggtaa caatatcgtt tttgctgcat gttctacagt agtaatacgt
    48601 attgtcccgg atgggcggtt ctgcagatcg ctcagggatg ccatggctga atctatgtca
    48661 tgcaacatag ggccaagaac agacaaaaga tgctcgcccg cttcagttgg aacaacgctg
    48721 cgcgtggttc gcgtcagaag ccgcaatccc aatcgttctt ctatacgacg cactatctgg
    48781 cttaaagctg actgcgccat gctcaggcgg gctgctgcac gagtgaagct acgctcctct
    48841 gcaacgacga caaacgccat cagatcagcg atttcttcac gcttcattca gtatctccat
    48901 gcaatctatt aatcatttaa atgataggtc taatcatgat tttgggtcta atcaacttaa
    48961 tgatcaatat ctatagtgat atcaccaacc gttaaaacga accgacaact ccatgaggaa
    49021 cggaatgatg aataataaag tcagcttcac taacagcaat aatccaacca tctctttgtc
    49081 tgcagtgatc tatttccctc caaaatttga tgaaacccgt cagtatcagg caattgtgtt
    49141 atctcaccca ggtgggggcg ttaaagaaca aacggccgga acctatgcca aaaaactggc
    49201 ggaaaaggga tttgtcacta ttgcttatga cgcatcttat caaggtgaaa gtggcggcga
    49261 gccgcgtcag ttagaaaacc catacattcg tactgaagac atcagtgccg tgattgatta
    49321 cctgacaacg ctttcttatg tcgacaatac ccgaattggt gcgatgggaa tttgtgccgg
    49381 tgcaggatat acagccaatg ctgcaattca ggatcgccgc atcaaggcca tcggtaccgt
    49441 tagtgcggtc aatattggtt cgatattccg taatggttgg gaaaacaatg tgaaatctat
    49501 tgatgccctg ccatacgttg aagcgggttc aaacgccaga accagcgata ttagcagcgg
    49561 agaatacgcc attatgccac tggcaccaat gaaggagtcc gatgcgccga acgaagaact
    49621 gcgtcaggcc tgggagtatt accacacccc tcgcgcgcag tatccaacag caccgggtta
    49681 cgctactttg cgcagcctta accagattat tacctatgat gcttaccata tggcggaagt
    49741 gtacctgact cagccgacgc agattgtggc gggcagccag gcagggagca aatggatgag
    49801 tgacgacctg tacgatcgag catcaagcca ggataaacgc tatcacattg ttgaaggcgc
    49861 aaaccatatg gatctttatg acggcaaagc ctatgtggct gaagcaattt cagtattagc
    49921 tccgttcttt gaggaaactc tgtaatgaaa catattcaaa tccgcaatag tgatatggac
    49981 tggcatattg ctgccaataa tctgggataa ttttcatgaa aaatgtactg attcttggtg
    50041 ctggcggtca gatagcccgc catgtgatta atcaactggc agataagcaa accattaaac
    50101 aaactttatt tgcccgtcag ccagcaaaaa tccacaaacc ctatccaact aataaaatgc
    50161 aaacaacttc cggcaaaaaa gtgatacaag atcgatgaca tagcgttgaa gaaaaggatt
    50221 tgataatccg caaaatttgc acaacactgc ctgtaatact tcctgaacca gagacgatca
    50281 tgaccgtaac ccgcccacgc gccgaacgcg gcgcatttcc gcccggaaca gaacattacg
    50341 gacgttcatt attgggcgcg ccgttaatct ggtttcctgc ccctgcagcc agccgcgaaa
    50401 gtggtttgat tctggctggc actcacggtg atgaaaactc ttcggtcgtc acgctctcct
    50461 gtgctctgcg gacgttgaca ccttctttgc gccgtcatca tgtggtgctg tgtgtgaatc
    50521 ctgacggctg ccagttgggg ttacgggcca atgctaatgg tgtggattta aacagaaact
    50581 ttccggcggc gaactggaag gaaggtgaaa ccgtttatcg ctggaacagc gccgctgaag
    50641 aacgcgatgt cgtattactg acaggtgaca aacctggctc cgaacctgaa acccaggcgc
    50701 tgtgccagct tatacaccgc attcaacctg cctgggtggt ctcattccac gatccactgg
    50761 cctgtattga agatcccaga cacagcgaat taggcgaatg gctggctcag gcgtttgaat
    50821 tgcctctggt aaccagcgtc ggttatgaaa cgcctggctc tttcggcagt tggtgtgaag
    50881 atctgaactt gcattgcatc accgcagagt ttccgcccat ctcctccgac gaagccagcg
    50941 aaaaatatct ctttgcgatg gcaaacttgc tgcgctggca tcctaaagat gcaattcgcc
    51001 cgtcgtgaac tgaagcgccg gttccacatc taccgccagc caggtcggtc cgtcaagatc
    51061 ggcgaaactg acctgcggca ccagcggtaa agcggcgcta atggcacgag aggtacacaa
    51121 catgcagccc agcatcagac tgaaaccttg tgcacgcgct tcagtcgcca gcgccagcgc
    51181 ttccgtcaga cccccggttt tatcgagctt aatattaacc atctcatagc gccctttcag
    51241 cgccttcaaa ttgctacgag tatgacaact ttcatcagca caaatcggca acggatgaat
    51301 aaaattctcc agcgccgcat cgtcctgcgc aggaagcggt tgttcaagca tcgcaacgcc
    51361 taaatccgcc aatagctggc aacgcgccgc caacccttct gcacgccagg attcatttgc
    51421 atcaacgatc agcgtcgcat cgggcacagc tgtgcgaatt gccaccatcc gctcactgat
    51481 aagatggtta tccagcttca ctttcagtaa tttcgcgcct gcctgccaga gtgttgatgc
    51541 actattggcc atctgatcag gcgtaccgat gacaaccgtc tgtgcagtga taactgtctc
    51601 gggaagcgtt atgccgatca aatcagccag cgattgctgc tgtcttcgcg cggccagatc
    51661 ccacaatgca caatccagcg cattacgtgc tgcgccggca gggagaattt tttgcaactc
    51721 ctcccgtgtc agccctttct ctagttgcgg cacgacgctc ataatttgcg ccattaccga
    51781 ggcatcactt tccccataac gcggatacgg cgtgcattcg ccggtgcctt taataccctc
    51841 ttcttccagt tcaaccacca ccacgcgcgc ttcactgcga cttccccggg caatcacaaa
    51901 cggggtatgt aagggccagg cttcctcgaa taccttaacg gttctcatct ttactccttg
    51961 ttgtcgcggt ggtctgcgga ttaagcgcaa atagcgtttg ctgtgttatt gacagttagc
    52021 ataaactagg tgtgacgtta actatatgta aacaggaaag ataatcatgt cacaaaccgt
    52081 tcatttccag ggcaacccgg ttacagtcgc caattccatc ccgcaggcgg gtagcaaagc
    52141 gcagactttt actctcgtgg caaaagatct gtctgacgtc accctcggtc agtttgcggg
    52201 taaacgcaaa gtgctgaaca ttttcccgag tattgatacc ggtgtttgcg ccgcatcagt
    52261 acgtaagttt aaccaactgg caactgagat cgacaacacc gttgtgctgt gtatctctgc
    52321 cgatctgccg ttcgcccagt ctcgtttctg cggcgcagaa ggtctgaaca acgttatcac
    52381 cctctccact ttccgtaacg ctgaatttct gcaagcttac ggtgtggcaa ttgctgatgg
    52441 cccactgaaa ggtctggcag cgcgtgccgt tgtggttatt gacgaaaatg acaatgtgat
    52501 tttcagccag ctggtggatg aaatcaccac cgagccggat tacgaagcag ctctggctgt
    52561 actgaaagca taatttaata tgcctgatgg tgttgcacca tcaggcatat tcgcgcttac
    52621 tcttcgttct tcttctgact cagaccatat tcccgcaact tattggcaat cgcggtatgt
    52681 gaaacgccga gacgttttgc cagtttgcgc gtgctgggat aattgcgata aagctgggtt
    52741 aataccgagc gttcaaaacg gctggtgatt tcgtccagcg aaccttccat cgcatcttcg
    52801 cccacggcta ccgttgcggc gtcataatcc ggcaacaaaa tatcctgtgg acgcagctca
    52861 taaccgtcca gttgtgtcag tgcgcgatag atagcgttct ttaactgccg cacatttccc
    52921 ggccacgcat aacgcgtaag tacagtattc aggtcagcgg ccagtttcgg acgcggcacg
    52981 ccctgctcgt cggcaaagcg ggcgacgaac agctcagtta acggcatgat gtcctgcgga
    53041 cagtcacgta gcggcggcag attgagcgtc aacacgttca gacgataata gagatcttca
    53101 cggaacatgc ctttttgcac cagttcgacc agattcttct gcgtagcgca aatcacccgc
    53161 acatcgacat gcacctcatg gtcttcgcca acccgacgga aagtgccatc attaaggaaa
    53221 cgcagtaatt tcgcctgcat ccgtggtgac atttccccta tttcatccaa cagcaccgaa
    53281 ccaccgttcg cctgctcaaa gaatcctttc ttcccttccg gagcatgacc aaacagttca
    53341 ctctcgaccg catcttccgg tatagacgca cagttcagcg ccaggtaagg tttgcccgct
    53401 ctggggcttg cctgatggca ggcgtaggca aagagatctt tacctgtacc tgtgtcaccc
    53461 gtaatcagca gcggcgcgct tagcatcgcc agtttctgcg cctgttcgac aacatgcttc
    53521 attttcgggc tgacggcgac aatttgactg aaggcgctga cgtcctgggc ggcgacattt
    53581 tgcaactggc ggcccatacg aatcgttgat cgcaacatca ccaccgcacc ggtcaggacg
    53641 tgttgatcat tttcatcctg aagataaaca ggcgtaatct ccatcaggaa attctgccca
    53701 ttaataacga catgctcgtt atgcgaatct tgcggttcgc tttccagcca acgtaaaaaa
    53761 ttaaagccgt taatcaattg tgcggcggta tggttgcgca ggcgatccaa tttttgccca
    53821 aaaagctgac agctcgccgg gttcgccata tccactttgc ttttcatatc gacagagagc
    53881 acaggttcag gcaacgcctc cagtaacgcg ctcaacgcca gatgctcacg ttcggaaggc
    53941 atccacggga cagtacgcac atcggtaaca cccgcaatac ggcgtatttc ggccatcaga
    54001 ctgctgaaac tctcaaactc cagttcagca aaattgaggt agattcgccc aatgggatca
    54061 atctcaatac cgcgtaaatc aatgcctctt agcacgagta gatcgagtaa ttcgcgggtc
    54121 agaccgagtc ggtcttcaca aaagacttcc agacgcatgg gaaccttcac ctgaaaaaag
    54181 aacaattaat atgatgatat gacactattt ggatagcagg aaggtttctg tcaacaatca
    54241 ttgacacaaa gacggaaaaa cgggcacttc ggcgtaaaga tatccggtca gcacccgata
    54301 ttgcattatt tttcgctggg cgttttgcct ttttgcagcg tttctttcac ctgaccgata
    54361 agctgacgac ggaaatcccc gaggcgaggt ttgtcatcgt caatccacgg cagcgggcgg
    54421 caaagctcca tagctttaat cccgagtcgt gccgtcagaa gtcctgcacc aatcccctga
    54481 gctgcgcggg tagacaaacg agcagcgaga tcttgcgaca tccagtccat ccccacttcg
    54541 cgcaccagtt cgctggctcc ggcaaaagcg atattcagca ataccagctt aaacagacgc
    54601 aaacggctgt aataccccag ttcaatgcca tacagcgtgg cgatgcgatt aattaaacgc
    54661 agattgcgcc aggcgataaa cgccatatcg accaacgcca gcgggctgac cgcaatcatc
    54721 aacgttgatt ccgccgccga acggctgatt tcgcgccgcg cctgggcatc taaaactggc
    54781 tggaccaaat gcgcatacag gctgaccact tcacggtcgt tttgcgtttc atggattgag
    54841 gcataccagc gttgcagcgc cggatgcgac tgatcaatac ccgcctgctg cgccagtttt
    54901 tcgcaaaatg cgcggccttt gcccgtgccg tggctatgca ataaatcacg cgcttcgtcg
    54961 cgttcatggg cgcgctgtcg caagcgccat aagcgccgcc actctgttac cacagaacct
    55021 acgccagcgc cgataatcaa tgccccagcg gcacatccac ccagcgccac ccagtcctgg
    55081 gtttgccagg cattcattgt ccactgtaca ccctgcccga caacgcttgc gccaaacaga
    55141 gccagccctc ccatcaccat tttgcgccac aggctgcgtt tcggacgtaa cgctgcgtcc
    55201 attaccgctt cgacttgccc ctcttcttcc tgcgcttcgt cgagcgtggc cggggcaaaa
    55261 ttttgcgcct gattttcgtc aaaggtctgc tgcgccctga atttaggatt ctgatcgacc
    55321 tccagaggac cgtcgaaatc aatacgtggt tttaacggtt cggtcatcgc aatttatctc
    55381 ctattaaaaa ttccagcgca gcatcaagac gaatatgcgg tagtggtttg tcgacatcca
    55441 tcacctgcgg acgaaatgcc tcaaactgga agccttgctt atcccagaac gcctgaccag
    55501 gcaaacgtgc gggaacttcg ccaggataaa cagtgagcgg tgcgccatcg ctaagtcgat
    55561 taccacgcag cgccgggatt ttctcaccgt taacatcaat aatgccgctg gtggtcgcct
    55621 gaactgacgc cagccccagg cagtccatgc tgatcccttc gaacgccgca ttttgccagg
    55681 catcctgaat cagttgttgc agtaatgaaa ccatattagc gtgctgatcg atggtcacat
    55741 ggtccgcttt agtggcagca aacaatagct tatcgataac cggcgaaaac aaacgccgga
    55801 acagggtacg ctgcccgtag tgaaaacttt gcatcagctg cgtcagtgcc agacgcatat
    55861 cattaaatgc ctgtggccca ctgttgagag gttgcaggca atccaccagc acaatctggc
    55921 ggtcaaagcg cagaaaatga ttcttataga accccttcac caccttctcg cagtaataat
    55981 taaagcgctc gcgcagcatt ccggcattgg tatgcttatc ggcctgcgcc agtttggact
    56041 cgccccaggt atcgacatcc ggccacggga agaattgcag cgcgggcgca cctgccatat
    56101 ctcccggcaa gacaaagcgc ccaggctgaa taaagtgcag cccctgctct ttacagtggt
    56161 ggagataatc ggtccacgcg gcggcaatgt ccgccagccg gttttcgtcg gcaggcgcta
    56221 gcgggtccag cccttcgctc atcattcgcc atttcgccga ccattctccg cgctgaccat
    56281 tgagtaagcc cgtcatctgg cgcgaccagc ttaaatagtc ctgcgccagc atcggcaggt
    56341 cgagcaacca ttcgccggga taatccacaa tttccagata cagcgtggag gtatccttaa
    56401 agtggcgtag cagcgaatca ttcgatttaa aacgtagcgc caggcggatt tcactgacgc
    56461 cgcgcgttgg cgttggccag gcgggtggat cgccatataa ctgcgccagc ccttcgtcat
    56521 aggtgaagcg cggaatgcca aagtcacgct ggggaatgcg tttcacgccc agcaggcgct
    56581 cttcacgcac cgcacttaac agcggcaaac gtgctccggc gtgaatatta agcaactgat
    56641 taaccatcgc ggtgataaac gctgttttgc cgctgcggct aagtccggtt acagcgaggc
    56701 gcagatgtct gtcgacaccc cgattcacca gcgcattgag ttcattttta agtcgcttca
    56761 ttgctgtcct gtgctgctct gaagaccaga aaaaaaatca ttcgtaagga tatgaatgtg
    56821 ggggccaggc cattgattat caactgcccg tgttgtcatc gaccggcgaa ctccataaga
    56881 tgtgcagcat tcacgttcgg acggagttcc tgacctatgt cccctactat ttatgatatt
    56941 gccagggttg caggcgtatc aaaatccacc gtatcacgcg tgctgaataa gcaaactaat
    57001 atctccccgg aagcgcgcga aaaagtgtta cgggccattg aagaattaca gtatcagcca
    57061 aacaagctgg cccgcgcgct gacctcttcg ggttttgatg ccattatggt gatttctacc
    57121 cgttcgacca aaactacggc gggtaatccg tttttctctg aagttttgca tgccatcacc
    57181 gccaaagctg aagaagaagg tttcgacgtg atattacaaa cgtcgcacaa tccggcagaa
    57241 gatctgcaaa aatgcgaaag caaaattaag cagaaaatga ttaaaggcat tattatgctc
    57301 agttcgccag cggatgagtc attttttgcc caactcgata aatatgatat tccggtggtg
    57361 gtgattggca aagttgaagg tcaatatgcc catgtttatt ctgtcgatac cgataatttt
    57421 ggcgacagca ttgcgttgac cgatgcatta attgaaagtg ggcatcaaaa tattgcctgc
    57481 ctgcatgctc cgcttgatgt ccatgtttcg gttgatcgcg ttaatggtta taagcagagc
    57541 ctggctgcgc ataatattgc agtgcgtgat gaatggattg ttgatggcgg ttatacccat
    57601 gaaactgcat taaaagcagc acggcaatta ttaagccagt caccgttgcc tgaggcggtg
    57661 tttgccactg acagcctgaa attaatgagc atttatcgtg cggcagcaga gaaaaatatt
    57721 gctattccgc agcagttagc ggtggtgggt tatagcaatg aaacgctgtc atttatttta
    57781 acgcctgcac cgggcggcat cgatgttccg acgcaggagt taggtcaaca aagctgcgag
    57841 ttattattcc gcttaatttc tggaaaaccg tcaccacaga atattaccgt tgccacgcat
    57901 atgacgctga aataaatacc agctaccttg cctgaatgcc agatgcgatg ctagcgcatc
    57961 ttatccggcc tacatttata gatcggataa agtactcgcg ccgcatccgg caatttagcc
    58021 cattatcaga acgagtaatt tacgccgaca cctgcataat ggaatttatc actgtcgcct
    58081 tcgtcgtgat cctgccactc aaacgcgtat tccagcgaaa cggaaagtcc gttctggaaa
    58141 tcataaccgt aaaataaacc tacacggtta aaatcatggc cttcacgttc aatatcatcc
    58201 tgccagtccc agttactcca gcgatccagc ccaatgcgcg tatacggcgt caccgagtgg
    58261 ttgccgagcg tcagcggcaa ataggcgcga atttcttgcg tggaaaactc accgttattg
    58321 cggctgtcgt ccatattgaa gccgcgctcg agataatagt tcactcgcaa ggcaaccgtt
    58381 tcgttgaagg tatattgcag acctgtttcc gtttcgacac gggtatcagc gtaaccggta
    58441 gtgttcagat cgttggcaaa tttatacatc gacaaccaac cgttgaaacg taaatcgtca
    58501 gtcagtttca catcccagtc tggcgcgatt ttccagcgct gcatattcgc cgtgtcttta
    58561 cccggttcat caacgtagtg ataaccataa ttacggaaac cgccggtcag gccgaaactg
    58621 aaatcatcgt tttcgaggaa ctgataatgc acctccagct ccgggcgatc aaaccacgtt
    58681 ccacgtttac ccgcgctata atctaccggc ccttcctgat aataggccag agcaattctc
    58741 cacggcccgt tggcggcatt aaaatagact gaaggctccg ccagcccatc catatcttcg
    58801 ccataaccct cgacgttttc tatttcgtac atcgcgccga tattaaagtg ccagtcgttc
    58861 ctttcctcgg cctgtgcgca ggccattccc gcacacatca ccagtgcggt acagggtaat
    58921 aactttttca ttattgttcc ttgtattatc ctgggggaat gccttccccc tgtatttagc
    58981 gaattgctat ttccgtttct gcatcaaaga aatgacattt cgtcatatca aaatgaatag
    59041 tgatattttc tcctgcatga taatcattta acgcaccagc acggaccact aactcgtgcc
    59101 ccccaaccgt ggtgtagagc ataaattccg caccggttaa ttctgccacg ctaattttgg
    59161 cggaaatgtt attttcctct tgcgcgtccg gatgaatatc ttccggtcgt attcccatca
    59221 cgatgggctt atgcaaactt tcctgtgttt tcagaaccgc taatttctct tcgggaatgg
    59281 ttaatttaag cgtttccgta acgaatttat cgccatcgat cgtgccgcga ataaaattca
    59341 tcgctggtga tccaataaat ccggaaacaa acatattcgc gggttggtta taaacggttt
    59401 tcggcgcacc tacttgctga acaatcccgt ctttcataat cacaatccgc gtcgccatgg
    59461 tcatcgcttc ggtctgatcg tgggtcacgt agatcatggt ggtgttcagt ttctgatgca
    59521 gcttgctgat ctctgcgcgc atttgcacgc gcagcttggc atcaaggtta gagagcggtt
    59581 catccattaa aaacacgccc gcttcgcgta caatcgcccg cccaagcgcc actcgctgac
    59641 gttgcccgcc ggaaagcgcc cccggcttac gtttcaggta ctcacgcagg ccgagaattt
    59701 gcgccgccca gttcacccgc tcatcaatca cctctttggc gattttttgc atcttcagac
    59761 caaacgccat gttgtcgtaa accgtcatat gcggatacaa cgcgtagttc tggaacacca
    59821 tcgctatatt gcgtgctttg gctggaacgt cattcattcg tttgccgtcg atcaacagat
    59881 cgccgccgct gatctcctca agcccggcaa tcatgcgcag ggtggtcgac ttaccgcagc
    59941 ccgacgggcc gacaaacacg atgaactctt tatcggcaat ttccaggttg aagtccttca
    60001 ccacatgcac ctggttatcg tagatttttt gaatatgttg taacgaaagc tgagccatgt
    60061 tgattccttt gctatacgtt ttgccagaag gccgataacc gcggccaggt gagtgattcc
    60121 gttgaaggca acagtaattg cgccccggtt aagcccgcgc cgatccccac cgagcgcata
    60181 ccgctggcgt taatggcgtc aatgcccgcc tgcgcatctt caatgccgat acatgcctgc
    60241 ggcggcacgc ccagccctgc acaggcggcg agaaagattt ccgggtccgg tttcgagttt
    60301 ttaagttggg aagcatccgc gcagaaggtg aaaaactcgc gcagctccag cgccgctaaa
    60361 atcgtcggcg cattcaggga gacagaagcc agcccaaccg agatctgctg tgcacggaga
    60421 tctgccagca aagagcgaat gccgggtaga acagcgttga ccgtcaactc gcgtagtgag
    60481 tggacataga gcagattttt gcgatacgcc agttgcgccc tctcctgcga gttaaagtcg
    60541 ccctctttgc ccccgtgttg cagaatgcgc cgcagagact catcgcggct gatccctttt
    60601 agggattcgt taaactgcgc atcaatgctg atgccaattt cagcggcaat ctgctgccac
    60661 gcctggaaat gcagatgcgc ggtatcggtg attacaccat ccagatcgaa aattacccct
    60721 tgcagtttca ttcatcctcc tgatgtttgg tagcggtccc attgaagggc aaaataaaat
    60781 cacccaaaca gaaaacagat tcttcagcca cggttataag ctgaccgttc aaacgcagtg
    60841 aaacgggcgc agaagttcga atcgcaatac gctgcgcgtc aagagtgacc tgtaattcgc
    60901 agccctgcca gaacagaggg aaagacaact gttgccactg ctcaggtaac gccggattga
    60961 gatgcaattc accgtcacgc acgctcaccc cggcaaaacc ctgaatcgcc cccagccaga
    61021 tagcgccagt tgcggcagca tggataccat catcacaact atgcggatca gcaccaagat
    61081 cgatttcagt cccctcgcgc cagaactgat aactttgggt cagcaggcca cagcgtgcgg
    61141 caacaatgcc gtggattgct ttacttaatg acgagtcgtg aatagtgcgc ggttcataaa
    61201 attgcagatt ggcaagacac gatgccgctg agaactgctc cggcagcatg taattgagca
    61261 tcaccacatc agcttgtttg aggatctgca tctcgttcac ttctgcgcgt gaataatcca
    61321 gcagtatggt ttgcttcccc gccgccgctt tgtatttcgc cagattaatc gccggcttag
    61381 ccataaacga atcatcctgc ggcaaaacgc cgtcgggctg aatttctggc atccatagct
    61441 ctttgaggaa catttcggcg cgatggataa acgcatcgtc gctacagccg aactggcggg
    61501 caatattcag cgcctgttga acgttgtagc gggccatata gctggtgtat gcattattat
    61561 tgacatgttc ggtatattcg tctggcccaa taacatcatg aatttccaga cgatcgttaa
    61621 ctctcaccgc gcggctaatc cagaactttg ccgtctccag aagtagcgcc atgccttcat
    61681 gcgcaatgaa actttcatcc cccgtggtct gccagtattg aataaccgcc caggcgatat
    61741 cggccaccag atgatgttcc gcctgcgccg aggccacttt ttgccgcagc ccggtgcgaa
    61801 tgttaatggc ggcaaattcc ggcgtctctt cttcgccgct gcgcgcgctt tcccacggaa
    61861 atagcgcgcc ctgccagccg ttgcgtcgcg ctttctcctg cgcgcctggc aagttgtgcc
    61921 agcgataacg cagtaaactt cgggcaaccg tcggatcgct aaacagatga aacggtaaca
    61981 aaaatacttc tgtatcccag aaaacgtggc ctttgtagcc ttcgccggtt aagccttttg
    62041 ccgcaatgct gctgcgctcg tcgtgggcag gcgtcatgat gcgcagatga taaagcgcat
    62101 aatctaacgc ttgctgatcg tgcgcttcgc cgccatttac cgtgatacga cgtttctgcc
    62161 accattgacg ccagttttct gttgatgctg caagaagttg gtcgtaactc tgctgcgcgc
    62221 acatttcaag ctggcgaagc gacgcgctgc cccactcgtc taaagcagct tgcctgtcat
    62281 cccgccagtc gatccacacc agtttttgca acgtcattgt ctcgcctgca tgaagctgcg
    62341 cactggtatg ttgcagtaaa cggcgctctt tggcggtata gcattgctgc acatcaccgc
    62401 tcaccttaca gcaacagctg atggccacat cactgcgtcc atcctgggtg gtgtagctcc
    62461 cctgcatcag atgctgacca aacacccgca cctgggtttc gtcgagatgt tggcgaccgt
    62521 gattggtttg cgtggcgtca atgcctgttg aaatcagcac tgacgcgtcg gcgtccagtg
    62581 gcgtaatagt gatttccagc gcaatgagcg gcagttggtc tgccgaaaca aagcgacggc
    62641 tggcgatggt gtaacctgag ccgttgctgg tacgccagac aacattgcgg cgtaattcgc
    62701 cactggcaaa gtcaagctca cgctgccagg cttcgtggga taacgagaaa acctcaccat
    62761 ttatggcaat ctccatcccc acgacatcag gcaggttcac cagttcgttg atttcacctt
    62821 ttcccgcccg atgatacagc cccgccagat acatccctcg cgtctggcgc gtgtaatctt
    62881 cttcatggct ggcgcgaagc ccaagatagc cgttcccctg cgccatcagc gatgcatact
    62941 tgttcagggt atgctggctg aaatggggtt ctgataacgt tactggcctg gtcataattc
    63001 cacacgcgtc cctgtttctg cggattgata caacgccgcc accagttgct ggatgatgta
    63061 cccctgctcg gcgtcggcta tcatcacggg cttgccctgt acgtgattga taaaggcttc
    63121 catgctgcgc aaatggcggt tgtcgtctgc catttcccgt tgcatcagcg tcattaattc
    63181 accgttgtta tcggtgtaga tatgtgctgg aaacagcgtc gcaccagctt tatcaccaca
    63241 aaagctgacg ttcataatcg actgttcgcg gatgttgagt gcaaatgacg tttccagcca
    63301 cagaatgccg ccgttatgaa attcaatggt gccaaacagc gaatcttcga cgctgtaagt
    63361 tgccggatcc cactcaccaa attgaccaca gctcttttgc gtgccgatct tttgaaagct
    63421 atgcgcattc acgcttttca ccgccggaaa gcccagcaca tacatcgcag catccagcat
    63481 atgaatgccg atgtcgatca gcgggccacc accctgcagt tctttattgg taaagacacc
    63541 ccagccggga acgccgcagc gacgcagggc gcgggcggtg gtaacgtaaa tctctcccaa
    63601 aacgccgttg gtcacctgtt cacgcagctg ttgcgtatcg agcgcaaaac gatggtgaaa
    63661 gtcgtaggcc agcaccttgc ccagtttgcg cgcggtatcg cacatttccc gcgcctgttc
    63721 tggcgtcatg gcgggcggtt tttcgcacat cacatggcag cccgcttcca gtgccatcag
    63781 ggtatgttcg taatgaaaac ggttaggtga gcagacgcta accacatcag gtttcaccgc
    63841 cagcagcatg gcctgcggat cgtcccacac ggatgcattc ccgtattttt ctgccagcgc
    63901 ctgcgcctgg gaaaggcggc tgtcacagac agccaccagt tccagatcgt tgcgggtgca
    63961 gtagtacgaa gcatgaacct tatccgccac ctggcctgcg cctattatcg cgacccgcag
    64021 cggagagctt gtcattgcac ttttcacaaa gacctcttag caggtacgca accaggccaa
    64081 cgaatcacgg tacgcctggg caggatcttc cgcccggata cgcccttcgt acactacata
    64141 gccctgatag ttatccgcgc gcagctgttc aaacagcgcg tggaaatcca gggtgccgct
    64201 gcccggctgg tagcgatggt tatccgcaat atgcacatga ccgagcaggt cgcggttgtc
    64261 atgcagcgcc tgcgccaggt tatcttcttc gatattcatg tgatagaaat cgccgataat
    64321 ctgtacatgt ttaagatcgt tttcgacgat gtaacggcgg gcatcggcga gggtgttgat
    64381 catatgatcc tgatagcggt ttaacggttc gagatacacc acggttccgg tacgcgcggc
    64441 gacctgttcc agtacgcgca gggaatcact caccattttg cggtcgccgt ccaggctacg
    64501 cggcgaggtc atcggcggta agcggaaggt aaacatgccc cacgcagccg gaacgacgat
    64561 gcctttaccg cccacttctg ccagcgcttc gagaatgcgc tcgatctgct ttaagccatt
    64621 aagacgacgc tcttcgataa agtcgccaat ccatccgtca tagccaccgc aggcggtggt
    64681 caccggtaaa ccggtttctt tgatcgccgc tttgacttct tcgatgttgt taaccagcag
    64741 tttgccgtca atctcaaaac catcgaagcc catctctttg atataacgaa atttctccag
    64801 aatgttttcc ggaaagaacg cctgattctg tgtgccgatt ttcatttttt tcattccttt
    64861 gaattaaaac gtaacgccca ttttgatgct ctgttccgga tgctggtcga catactgcat
    64921 atagctttcc gggctattgg caaaggtcac caccgggtcg attaaatctt cgcaattgag
    64981 ataaccgttc atcagcagtt cccaacaggt ttcttcaata cgcttgcggc tccagcgcgg
    65041 ataatccggg ttcggttcgc tgcacgcgcg agagaagaca attttggcgt tattgaaatg
    65101 cgcttcgcgt ccgaggttaa aaccttcggc aaacggcttg gcaaacgcga cataggagat
    65161 ggtgccgcca taagccagac cgcggagcgc cgattgcagc gcgtcggcgt agccgctggt
    65221 ttcgataatc acatcggcac cctgcttgcc ggtcagcgtt ttgatctctt tacctacatc
    65281 agtgccgatg gggttaaggc agaaatccgc gccgtggcga cgggcaatat cacagcgatg
    65341 ggcgatagga tcgacgccaa tcaccacaga agcgccagcg cgtttagcca gttggatggc
    65401 aatttgaccg attgcgccaa gccctaccac caccacaaaa tcccctacgc gcacgttggc
    65461 atcgcgcacg ccgctcatgg caaactgcgc cgggtcgtag cagacggcgt ttttccagga
    65521 gctgccttgc ggcattttgc gcagcttgta gttattcact gcgttaatga tgaccgtctc
    65581 ggagagcggg ccgtagccgc atacgctgtc gcccaccgcg tagtcggtaa cgtcgctgcc
    65641 gcactcgata atgtcgccaa ccaccatgtt gccaagctgg aatttgccaa actcaatgcc
    65701 gcgcggcgca tctgccggac gcggagtgaa catctgccat tcgccgttaa agtcttcatc
    65761 aataaacggg ctggcggcgc ggaagtcgac cacttccgtt ccgtgtttcg gtgcgccgaa
    65821 acgcacgcgg atcttcactt cattagctaa aatcgcccga tcttcatact caaccagcgc
    65881 agcaacacgc ggtgctgtgg ctactaactt tttcatttaa aactccttgt aaagaaactg
    65941 gccgctttag cccttcacgc caccggcggt caaaccactc ttaataaaac gttccgaaag
    66001 cgcatacata atcaccaccg gcaatgcggt caccagtgag gccgccatca tccgtcccca
    66061 gatgtaatct ggcgtactga acagcgcgtt caggcccacc ggtaaggtga aattgctggc
    66121 gctggagagg aaaatcgacg caaacagata gtcgttccac gccaccataa agcagtagac
    66181 gaacacggat atcagcccgg acatcgccaa cggcacggtg atgcggaaga taatttgcag
    66241 acggttgagg ccatccatca tcgccgcttc ttcgatctca tcggggatgg tgtcgaagta
    66301 gcttttcagc ataaacacgg cggtgggcag agtttgcgtc accatggtga tgatcagcgc
    66361 catctcagtg tcgtaaatgc caagcgcggt gatgattttg aaaagcggca ccaccagcaa
    66421 aatgccagag aacatataca ccgtgtaaaa gctggcgttg atggtcatcc gacctttaaa
    66481 gcgcaggcgg gaaagcgcgt aagccccaag aatgccgagg aataccgcca ccacggatga
    66541 aaccacagac accaccagac tgttacggaa gtagtcgaca aacgggaaaa tcatcgggtt
    66601 aaaaatgtcg acgtaatgct ccagcgtcca ctgctgcggc agcagcgtag gatgcagtga
    66661 gatcgcctct ttcgcgccct tgaacgaggt catcagcatc acaaaaaatg gaaacagcgt
    66721 gatgatgaga aacagcgcca gcccgcagta aaaaccgatg cgactgagtg tgcgtttatt
    66781 tgttgccatt gaggttcacc cgtttcctgg tcagcagaat gacagcgaaa ataatgatga
    66841 agagcaccac cgagatcgcc gccgcttttc ctaaatcatt aaaggcaaag gcggttttgt
    66901 agagatatac accgagaata tcgaccttgg tcgtcagcaa ataaacatcc gcgaacatgt
    66961 agaacatcca gatggtgcgc agtgtcacca ccgtcgccag gaccggcata attgcgggca
    67021 gcgtgacgat acgaaaccgt tgccaggcat tagcgccatc catctctgcc gcttcgtaca
    67081 gcgatttgtc gatggtctgc aaaatcgcca gaaacgagat aaaggcatac gggaagtagc
    67141 gccagatggc gaacagcacc accagcacaa agctactgcc cggattatcg aaccacagcg
    67201 gtgcctgctc atagagatgc agaagatcga cgccgaggta gttaacaatg ccgtagccgt
    67261 tgttgaacat gtatttccag gcgaacacca gcgaaatgga cggcgttacg taggagagga
    67321 tcaccagcga acgcgcggtt ttgcgcaggc ggaactcgcg gttgaaaaac atcgccaccg
    67381 ccagcccgag cacggtgctg cccgccacca ccagcgcggt ataccagacc gtcatccaca
    67441 gcgaatgcca gaagccggga tcggagagga tacgcacata gttgctcacc ccaacaaacg
    67501 ttgactcgat gttgggattg agcggcagac gtaaaaaact gatttcgata ttcgacacca
    67561 tcggccacgc caccagaccg cccagcagta ataagctggg cgcgagaagc agcagcgcaa
    67621 agggcatatc ggaacgacct gaaaaaagcc tgttcattgc ggattcctgt cctgggttta
    67681 gtgctgttcg atcagttcat ccagtttttt ctggctcgct tgcagcgtag tagagagatc
    67741 ggctttaccc acggtgacgt tatgcaccat tgaactcacc acgccagaac ccgtcacatc
    67801 acccatgcgg gtaaagtttt tatcccctac tgcgccaaaa acctgaatat ttggcagttc
    67861 accgattagc tgattcggta gttcacccag cgccttaata acgtcgttgt ctttccaggt
    67921 ggcggtagtc accaccgctt tattcaccgg cagcgcagca cctggcgaca tcatcaccca
    67981 gtcggcaatg ttgtctgcct gctccataaa ggtgacaaat ttttctgctg cttccgtctc
    68041 ttcggtcttt tgcccggcgg taatggtcag cgaggtcaac atgccgtaga ccgcagagtt
    68101 tttctcggtt ggcaccacga aaccgacgtt tttcgggtcg ccttctttaa tcacagccgg
    68161 aaggatatag gtggagtaaa tcgccatcgg cgcggtgccg ttcataaagg cgtctttcac
    68221 ttccatgatg tcgttagaac ccggcatagt gttggcagca aggtcgcggt aataggtcag
    68281 tgcctgcatc atctctggtg tatcaagggt gattttgcct tcggcgttaa agacgttagc
    68341 ctggttggat aacgcaaact gggagaagga ttgttccgtc aacacgcttt ctgctgtagg
    68401 cagcgcaatg ccgtattttt tattcgccgg gtcattcagt ttctgtgcaa cgtccagcag
    68461 ctgttgctag tttttcggct cctcaagccc cgcttttgcc agcacatctt tgcgatacca
    68521 gataccgcca atccaggcgc tgacaggaac accggtccat gcgctaccat cttcggtacg
    68581 cacaatacgc agtacgccat cgtaaaacgc gccttcacca acgttgctga tgactgtggc
    68641 aaccgctttg cgatcgataa gctgctcttt gtccatcact ttggcgtagt catggctggt
    68701 ttcgatcact tccggcagcg aaccgctacg tgaaagagta atgactttag tgttataggc
    68761 atcttcttcc acgggcactt gcttaacggt gatgccaggg ttttcttttt caaaacgggc
    68821 aatcaattta ctgataacgg cctggcgctc ctgctccacc gaagaatgca taaattcgat
    68881 ggatacattc gttttatttt cttctttaca gcctgaaatc agggcgcatg aaaccagtgc
    68941 tgataacagc acgatttttg atttaatcat gagatgttcc tttttattta atccacataa
    69001 cctgccaggg gcgcagcgtt atttcattac ccaatatatc aacttcacta atcagatccc
    69061 gaccatgcag attagtaata tttacatgct gaatattttt actgacatta aacaatccag
    69121 tcagacaatt accatcagcg ttacttcttt gaatacgcat tacggatgaa ttaatcgtat
    69181 caatggtaaa attattatcc ggatgaaact cgttatggct gcgacgaagt gtaattaaac
    69241 gcgacaactc atgatatacc gcatgcctta atgtagcttc atcgttcagt tctcgggtta
    69301 tctctttact gtgatatttt ttacggttaa tcgcacggtt atatccgagt ttttcgacac
    69361 ctgcgtaatc attacgcgag ccaagaatac tttgaatata tatcgctggc acaccgggga
    69421 aacttaacaa aatcgcatgg gcaaggataa acctggcgca acgttcttca tcgctactct
    69481 cacggcggct taacgcatcc atataggtca catttatttc atacggactg cgtgtaccgt
    69541 cgggattatt tttccagttt actaatgcac cttcctgctg taacgcctcg accagctcta
    69601 atatttcgct ttcaggcaac aagccccgta gcgggtttag cccgatgcca tcgtgagagg
    69661 cgaggaagtt aaaccaggtg gtgttgctgg aaggtagtgt caggttttgc gcccacgcac
    69721 aaagcgcctc aacgttctgt ttttgcaccg catgcagcac cagtggcggc agcgagaact
    69781 ggtacaccat atgtgcttcg tcatcgcctg cgccaaagta agcaatgttg tctttatgcg
    69841 gaacattggt ctcggtaatg atcactgtac ctggcgcaac gttatcaata atcgaccgta
    69901 acagtttgat aatcagatgt gttttttcca gatggatgca gcttgttccc ggctctttcc
    69961 acataaagcc aacggcatcc aggcggacat actcagcacc tttcgcaagg taacagagta
    70021 aaacatccac catcgccagc aacacttcag ggctacggta attcaggtca atttgatcgt
    70081 cactaaaggt ggtccataaa tggcgcgttg aatgatcgcg catctggaat ggcgttaata
    70141 acggtaacgc acgcgggcga gtgacggcgc tgagatcggt ttgcgggtca acggcaataa
    70201 aaaaatcttc aaaacctgga tgctgttgta aatagttttt aaaccattca ctttttgccg
    70261 acatatggtt gcagacaaaa tcaaacatta aatgactgca ttcaccgagt tgctgaatat
    70321 cctgccactc ccccgcttca ctggcgacct gatgataatc aattaccgaa aagccatcat
    70381 cagatgacca tggataaaac ggcaacaaat gaacatgtga aaaaatgctt tgcagccatt
    70441 gatggtaaaa ctgattaaat gtgggtaatg gttttaaatc attgctgtga aattgatcgg
    70501 cataggtaat taacacgaca tcactttcat cccagtgttt tttacgtcgc tgtgtaatta
    70561 atcgtttcgc actctcaaga cgcgttacaa gtttctgtaa atgagttgcg gtaaatgttc
    70621 caccgtagat ttcgtccagg taatccgtaa ttttctgttt catgttgcct ttccgtggta
    70681 gcggtcccat gaaacgagag actactccgc agaaaataaa ctgtcaattg agcacaaggg
    70741 ttttagtcac gcaggaaatc attttttacc agggaaaaag cgtatttgtg agctgacgca
    70801 aataatctat ggggatgtaa ataaggtgtg acagaaaaaa aaacggcgca taagcgccgc
    70861 tcatggtgaa ttcttttaac ctttgacctt cggcattgcg atgtctttca ggccaccggc
    70921 gttctcaacg tgggtatatc ccatctcgct aaggatctct tttgcttgcc ctgactggcg
    70981 tccggcattg caatacactt tcacggtgtc gtttttatcc ggaacggcgg tggcaatgcg
    71041 ctctttcact tccttcaggg gaatattgat ggccccctga acgtgctctt gctgatactg
    71101 ctctggaaca cgaacatcga tccagtgttc agcggcgaaa acgggcagtg aaaacaccag
    71161 tgccagagca agtaagcctt ttttaaacat gtaagcgtcc ttctatggat gaaaattgcc
    71221 atccattata cgcctgagat ttaacaattt ttgcgaaact cccctcacct tttataacgc
    71281 tgtgccagtt tattagcagc ccgacttaac agcggttcca gcgccacagc cagcaacatt
    71341 ttcagcggtc ggcgagcaac tgattttatc gcccagcccg ccacacccgc cgggccatag
    71401 cgcagtgcgg taagaagtac cagcttgcct gctaatttga aaccaggctt taccttttgc
    71461 ccggcctgtt gccagcgagt attcataact ttcctcacag ttgacggaaa cggctacgta
    71521 acgtgaaagt atcggaagtg acataacgtt ccatctcgcg taaacgcgtt tcacttgccg
    71581 ccagttcacg gtcgacttca tccagcaatt cgctgctgga aggtagctgc tcaccaaagg
    71641 ccatgttgtc cggcattgga tcaagcgcaa atgacaaaat gatgtaagca accagggtaa
    71701 acagcgccag accgaagaaa atcgacagca ccaccaggat acgcaccagt tttaccggta
    71761 catcaaaata gttggcaatc ccggcgcaga cgccgcggac catgccctgc tgtggaatac
    71821 gccataattt tttattgaga ttaatgcccg ccattagcga tccctccagt tcggatgttc
    71881 tgcatcaaga atagattcca gcgcctgaat acgttcgcgc atccgttttg cttcatcagc
    71941 cagttgcgct aatcgctgct gctcactttg cgacaattca ctgcgaccag aacgattgct
    72001 gtaatgcagc cataaccaga tcggtaaaac aaacagcaca aaaatggtta acggaatagc
    72061 cagaaatagc gcgctcataa gtactcctta gacgatgagc ggcggcgcgt tcggacgccg
    72121 cctggatgtt attattgatt gtcttgcttc attttggctt ttaattgtgc cagttgttcg
    72181 ctgattgcat catcggcttt cagttcggca aactgatcgt ccagcgattt ttgtttaccg
    72241 aagctgtggc tttctgcttc cgcttccatc tggtcaatac gacgttcgaa agattcgaaa
    72301 cgagccattg cttcatccag tttgccactg tccagctgac gacgcacatc gcgcgacgag
    72361 tttgccgcct gatgacgtaa catcaatgcc tgctggcgag cgcgtgtttc gctcaatttg
    72421 ttttccagct cgccaatctc tttcttcatg cgtgccagcg tatcgtccac cagcgtcact
    72481 tcatgttcca gggacttaat cagatcggtc agtttctgtt tttcaattaa cgctgcacgt
    72541 gccagatcct ctctctcttt cagcagcgcc agttcggctt tttcctgcca ttcaacctca
    72601 cgcgccgacg cttgttcaat acggcgagtc agctgtttct tttctgccaa cgcgcgcgcc
    72661 gaagtagaac gtacttcaac cagtgtatct tccatctcct ggatcatcag acgaaccagt
    72721 ttctgtggat cttccgcttt ctctaacaga gcgttgatgt tggcattcac gatgtcggca
    72781 aagcgagaaa aaatacccat aatgttgtcc tcttgatttc tgcgttcagg attgtcctgc
    72841 tgaactgtta atacaatttg cgtgccaatt ttttatcttt ttgatttata aagatctgat
    72901 tgaagaatca acagcaacat gccaggatga gttagcgaat tacactaaca agtggcgaat
    72961 ttcatcatgg cagaatacaa agataattta cttggtgagg cgaacagctt tctcgaagtg
    73021 ctggaacagg tttcgcatct cgcaccgctg gacaaaccgg tgctcatcat cggcgaacgc
    73081 ggcaccggta aagagctgat tgccagccgc ctgcattatc tctcctcccg ttggcaaggg
    73141 ccgtttattt cccttaactg cgcggcgtta aatgaaaatc tgctggattc cgaactgttt
    73201 ggtcacgaag cgggggcgtt taccggtgcg caaaaacgtc atccagggag atttgaacgt
    73261 gccgacggcg gtacgctatt tcttgatgaa ctcgctacgg caccgatgat ggtgcaggag
    73321 aaattattgc gcgtgattga gtacggtgaa ctggagcgcg ttggcggcag ccagccattg
    73381 caggtgaatg tgcggttggt atgcgcgacg aatgccgatc tcccggcgat ggtcaatgaa
    73441 ggcacttttc gcgctgacct gctcgaccga ctggcttttg atgttgtaca actgccacca
    73501 ctgcgcgagc gcgaaagcga cataatgttg atggcagaat actttgccat ccagatgtgt
    73561 cgggaaatca agctgcctct gttcccgggg tttacggagc gcgccagaga aacattgctg
    73621 aattatcgtt ggccgggaaa tattcgtgaa ttgaaaaacg tggtggaacg ttcagtgtat
    73681 cgccacggca ccagcgatta tccgcttgat gacatcatta ttgatccctt taaacggcgt
    73741 ccgcctgaag acgctatcgc cgtttcagaa accacctcgc ttccaacact gccgctggat
    73801 ttacgtgagt ttcagatgca gcaggaaaaa gagttgctgc aactcagttt gcaacaaggg
    73861 aaatataacc agaagcgcgc ggctgaatta ctggggttaa cttatcatca gttccgcgcg
    73921 ttgttgaaaa agcaccagat ttagcgaagt tgagcaatac aacttgccgg atgcggcgtg
    73981 aatgctttat tcggcataca taatcaatac gtcgtttgca ggcctgataa gcgcagcgca
    74041 tcagacatta ttgcgttggg ctattaatcg ctcagcgcat cctgcaaaat tttcattgcc
    74101 gcatcgaatt gcgcatccgg gatggtcagc ggatacagga agcgaatcac gttgccgtat
    74161 gcgccacagg tcagcaggag cagcccctgc gccagcgcgc gttgctggat tttctgtgca
    74221 atcgccgctg acggctcgcc cgtttgcgga tcgttaaact ctaccgcaat catcgacccc
    74281 aggccgcgta ccgcagcaat ggccggaacg ctttctttgg catcaatcaa cgtgtttttg
    74341 agacgctggc ccagttgatt cgcgcgttcg cagagtgatt ctttgtcgat aatgttgagc
    74401 accgcgtgcg cggcagccac cgccagcggg ttaccggcgt aggtgccgcc aagcccgccc
    74461 ggcgcgggtg cgtccataat attcgcgtta ccgaccacgc ccgaaagcgg catcccgccc
    74521 gcgaggcttt tcgccatcgt cattaaatcc ggcttatcgg cgtaatgatc catggcaaac
    74581 agcttaccgg tacgcgcaaa gccgctttgc acttcatcag caatcatcac aataccgtgc
    74641 tcgtcgcaca ggcggcgaat agcggcaacc agctcttttg gcgcaacgtt gaaaccgccc
    74701 tcgccctgca ccggttcgaa aataatcgcc gccacctgct tcgcttcgat gtctgattta
    74761 aacaagcgtt cgatggcgtc gagggagtcc tgtgttgaaa tgccgtgtaa atctgacgga
    74821 taaggtacgt gatacaccga accagggaac gggccgaagc cgattttgta cggcgcaact
    74881 tttccggtca gcgccatggt catatacgta cgaccgtgaa agccgccgct aaacgcaatc
    74941 acgccagggc gtccggtatg ggcgcgagca attttcaccg cgttttccac cgcttccgca
    75001 ccggtggtga agaacgcggt tttggcctgc ccgctcaccg gggcaagggc gttgattttc
    75061 tccgccaggg tgacgtagct ttcatacggc acaatctgat acgcggtgtg ggtaaactgt
    75121 tgcagttgct gctccaccgc cgcgaccaga tcagggtggc gatgtccggt attcagcacc
    75181 gcaatgcctg cggcgaaatc gatgtactcg ttgccctcaa catccttcag cgtggcgttt
    75241 tcagccgact gggcgaagaa gttacacatc acgccaaccc cgcgcggagt ggcagaaaga
    75301 cgacgctgat ggaattcatt gttgctcatg tttcacacct tttgactctt cacggttaat
    75361 cggaaattaa acgcccagac gatcgcgcag gctgtaatac gccgcgccca tcgcggtaaa
    75421 cggcacacgc agcgtgcgcc cgccggggaa cgggtaatgc ggcagattgg cgaaggcatc
    75481 gaaacgttcg gcgtcgccgc gcagcagttc ggcaatcaaa cgtccggcta gatgagtaca
    75541 ggtcacgccg tggccgctgt agccctgcat gtaatagatg ttggtatcga ggcgaccaaa
    75601 ctgcggcata cgcgacaggg tcagcaggaa gttgcccgtc cagcggtaat caattttcac
    75661 gcccttcagc tgcgggaagg ttttcagcag tttcggcacc acaaggcgct caacgtcatc
    75721 cgggtcgcgc gcgccgtaga ccacgccgcc gccgtacagc aggcggttgt cggcggtaag
    75781 acggtagtaa tcaagcagat agttacagtc ttccacacag tagtttttcg ggatcagcga
    75841 acgggctaaa tcttccgaca gccgttcggt ggtgatcacc tgcgtgccgc acggcatgct
    75901 gcgtttcgcc agttccggct ctactttatc gcccagatac gcattcccgg cgacaatcac
    75961 atacttcgcc gtcacctgac ctttggcagt tcgcacaacg gctggcgtgg tgtgctggat
    76021 ctgcgtcacg gcagaaagtt catacacgcg cccgccgttg aggcggatgg cgtccgcttc
    76081 gccaatggca aggtttagcg gatgaatatg cccaccgctg tgatccagca gcgcaccggt
    76141 atagcgatcg ctggctactt cacggcgaat ggcgttggcg tccagcaatt ccagctgttt
    76201 attgccgtag cgttcccagt tctctttctg ctcttcaagt gtggcgagct gtttatcatt
    76261 catcgccaca aacaggccgc cggggcggta gtcgcagtca atctgataac gtttgatacg
    76321 ttcgcggatg atctcaccac cttcgaacat catgctgccg agcatacggg cggtgtccat
    76381 gccgtagctt ttttcgatca cgtcgatgtc gcggctgtag gagttcacaa gctgtccgcc
    76441 attgcgcccg cttgcgccaa agccgatgcg tgaggcttcg agaaccacta cgtcaaagcc
    76501 cgcttccgcc agatgcagcg cggaggagag cccggtatag ccgccgccaa ccacgcaaac
    76561 gtcgcaggtg attgactcat tcagcgtgtc gaatggtgca tatttattcg cactggcggc
    76621 gtagtaactg ctggtatgtt cggtcatttc aggcctccag gcttatccag atggttttca
    76681 gttcagtgaa tttttcaagg gcatgcaggg atttgtcgcg accgttgccg ctctgcttat
    76741 agccgccaaa cggcacggtc atatcgccgt cgttgtagtt attgacgaag acggaaccgg
    76801 ctttcaggcg tcggctcatg cggtgcgcgc gggagaggtc gcgcgtccat accgccgcgc
    76861 caaggccgta ctggctgtcg ttggcaagct gtagcgcctg ttcttctgat gtgaaacgcg
    76921 tgaccaccag caccggaccg aaaatctctt cgcgacttaa ggacgcattc gggtccacat
    76981 ccacaaagat ggtcgggccg atggcggcag ccagcccggc gttacggcca tccaacaaca
    77041 gttgcccttt gctttcgcct tcccgaataa agctatggac cgagtcggcg tgggcgcagt
    77101 cgattaaggt gcccatggtg gttgcgggat caagtggatg gcccggctgc cagttttgcg
    77161 cctgctgttt taacagggct aagaattcat cggcgatgct ctcttccagc aacaggcgcg
    77221 ttccggcgat gcacacctgt ccctggttgt agaaaatgcc tgctgcggtg gcgcttgccg
    77281 cctgttgcaa atccgggaag tcagcgaaaa cgatgttggc gcttttgccg cccgcttcca
    77341 gccagacgcg tttcatgttg ctgtcgcccg catctttcag cagctgtttc ccggtacggg
    77401 ttgaaccggt aaaggcaatg gcgtcgatat cgttatgacg cgacagcgcc tgcccggctt
    77461 catgaccaaa acccgtcacc acgttcaaca caccatccgg caagcctgct tctttcgcca
    77521 gccccgcgag acgaatcgca ctgagcggtg atttttcaga cggttttaga atcacgctgt
    77581 ttcccgccgc cagcgccggg ccgagtttcc agcaagtcag caacagcggg aagttccacg
    77641 gcacgatggc ggcaatcacg ccgaccggtt cacgcacgat catcgccagc tcatggctac
    77701 tggtggtcgc cacttcgcca tacactttgt cgatcgcttc ggcgtaccag cgaatggcgc
    77761 gcgccgcgcc gggaatatca tcacgcagac tgtgacgaat cggtttgccg gtgtcgagag
    77821 tttccagcag tgccagctct tcggcgtggg cttccattaa atcggcgagt ttattcagta
    77881 ccgctttacg tttagccgga gaagagagtg accagtcgcc gcgttcaaat acgccgcgtg
    77941 ctgcgctcat cgcacggtcg atatcgacgc tcttgccgcg ggcaattttc gccagcggtg
    78001 cctgggtgac cggatcaacg gtttcaaagg tttcattttc cgccgcagca gtatattcac
    78061 cgttaataaa taagcggttt tcaatggcga gacttaacgc tttatcctgc cagtaagcca
    78121 gatgatgaaa attcattatg actcctgttt cacgtctatc agatatatgc agtttgtgaa
    78181 cgtcagggcg cagagatccc cgggccgtat gcccgtttat ttctggcgac attctttata
    78241 tacacttcat ccttcaagcc gcctctgcct tggctgcgtt cgctcccccg aatcacttac
    78301 ctgagtaagc tcatcgggat tcgctcactt gccgccttga tgcaacttga atgattttgt
    78361 gtatagattg ccgggcgcat tgcgcttacc cggcttacag aacaaaaaga ttaaaacgtg
    78421 gtgggcgtat gggcgctgat aattcggcaa atacctgccg acgtattact gaaactgtgc
    78481 gggatgccgg tattaatggc ataactttgc cccgcgacga ggtggtaatc ctgaccatta
    78541 atcgtcagaa caatttcacc ttccagtaca gtgcctattt cctcaccctg atgcttaatt
    78601 ctttccccag tggttgtgcc cggctggtac gtttcaaaga tcatcgccag cgtgcgattc
    78661 gggttaccgt tatgaaccag cttcattgac acaccctgac tacccatctc aattaagtcg
    78721 tcctgattaa tgacgacctg cggctcatca ggtttttccg gctcggaaaa gaattccgag
    78781 agtgacagac catacacctt cagcagcttt tgcagcgtac tgatggcagg gctgacttta
    78841 tcttgttcta tcgtactgat agcactgtga gtcagcccgg agagttcggc ggcacgacgt
    78901 tgtgaaagcc cctgctgctg gcggatttcc gacaagcgtt ttcctggcgc cagtccctca
    78961 tcactcatat ttgcatttcc ttaaactgta gtggtcagag tcgctgtttt tcagcgatat
    79021 ggtgctgaca agcggtgata aagccctcga acaatatacg cgaaagcgcg tactcgctac
    79081 tgttccattc cgggtgccac tgtacgccca gcgcaaaagg atgattgatg acgctaaccg
    79141 cctcaactaa gccatccggc gagcgagctt caacacgcaa ccgtgggcta acgaccttcg
    79201 ccccttgtcc atgtagagag tttacccaaa agttgctaca ttcaggtaac aacgcagaca
    79261 gtaatccccc ctcttcaacc tgaacttcat gcgacggtgc atattgctgt tccaccggca
    79321 gttcgggatc ttcccgatgt tccagcaatt caggctgttc gcacagcttg cgatgcaacg
    79381 aaccaccggt tgccaccacc agttcttgta aaccccggca gatggcgaaa atggggatgc
    79441 gcctttcgag tgcggcatta attatcgcca tgctcagaag atcacgcccg ggatcggcgt
    79501 caggctcatc gccgttttca ccatataggt gcggctgcac attgctggga ctaccaggaa
    79561 gataaatgcc atcgagtttc ggcaaaagtt gttcaagtaa tgacggttcc gccagcgcat
    79621 gtggtagcgc aataggcaag ccgcctgcat ggatgatggc attcaggtac ttttcttgca
    79681 gagtctgggt cgcatgaccc ttaagcctgt tcctgcacat tacgacaccg ataaccggat
    79741 tgttcattat attttccatg ctcaatctca caaagtggac taaattatcg ccattactgc
    79801 gctttaaatg acctttatgt tcaatatttt ttcaatctag cagtgggttt tcatttttgc
    79861 aaactcaatt taacatttga caaacattta gtttgcatac agattcgaat ggtggtcatt
    79921 atattttacg ctttgataac gagcggaaaa caaaccaaag gcgaagaatc atggaaacca
    79981 atatcgttga agtagagaac tttgttcagc agtcagaaga gaggcggggt agcgccttta
    80041 cgcaggaagt gaaacgctac ctggagcgct acccgaatac gcaatatgtt gatgttttac
    80101 ttaccgattt aaatggttgc ttccgtggaa agcgtattcc tgtttcaagc ctgaagaagc
    80161 tcgagaaagg gtgttatttc ccggcctcgg tatttgcaat ggatattctg ggcaacgtag
    80221 tagaagaagc aggtctgggt caggaaatgg gcgagccgga tcgtacctgt gttcctgttc
    80281 tcggttcctt aactccttct gccgccgatc cagagtttat cggtcagatg ctcctgacca
    80341 tggtcgatga agatggcgct ccctttgacg ttgagccgcg gaacgttctt aaccgcctgt
    80401 ggcagcagct gcgccagcgc ggattgttcc cggtcgtagc ggtagagctg gagttctatt
    80461 tactggatcg ccagcgcgac gctgaagggt atctgcaacc gccctgcgcg cctggcaccg
    80521 atgaccgcaa tacacaaagc caggtttact ccgttgataa cctcaaccac ttcgccgacg
    80581 tgctcaatga tattgatgaa ctggcgcagt tacagctgat tccggcagat ggcgcggtcg
    80641 ctgaggcctc gccgggtcag tttgaaatca acctttacca tactgataac gtgctggaag
    80701 cctgcgatga tgcgctggca ctaaaacgcc tggtgcgtct gatggcagaa aagcataaga
    80761 tgcacgccac ttttatggcg aagccgtatg aagagcacgc gggcagcgga atgcatatcc
    80821 atatcagtat gcaaaataat cgtggcgaga acgtgctttc tgacgcggaa ggcgaagatt
    80881 cgccgctgct gaaaaagatg ctcgccggga tgattgacct gatgccgtcg tcgatggcgt
    80941 tgctggcacc aaacgtgaac tcgtatcgcc gcttccagcc gggaatgtat gtgccgacgc
    81001 aggcgtcgtg gggccataac aaccgcaccg tcgccctgcg tattccgtgc ggcgaccgtc
    81061 ataatcaccg cgtggaatat cgcgtggcgg gtgccgatgc caacccatat ctggtgatgg
    81121 cagcgatttt tgccggtatt ttgcatggcc ttgataacga gctgccgttg caggaagaag
    81181 tcgaaggcaa cgggctggaa caggaaggct taccctttcc gattcgccag agcgatgccc
    81241 tgggtgagtt tatcgagaat gatcacctgc gccgctattt aggcgaacgc ttctgccatg
    81301 tctatcacgc ctgtaaaaat gatgagctgt tgcagtttga gcgcctcatc acagaaacag
    81361 aaattgagtg gatgttgaaa aacgcgtaat accccttgcg gggttgtttc atcggcctga
    81421 gcggagccag gcctgacatt tgctggtaat ccagacattt cccggatgtc gcgttatgga
    81481 gcgcgggcgg caacgggctt ccgttaacga ttaagactgt gacgaggaaa tgagatgatg
    81541 ccgatgatta aatccccgca tggcgaggga ggctgcgtat gcgcccctcc tgctactgac
    81601 tggactccgc cccctttgct tcccttgcta aacaggtttg atttcaggtc gacacgaccg
    81661 caaaccttat tacgcagggg aggcagcaat tatggctatt aattcaccac tgaatattgc
    81721 tgcgcaaccc ggcaaaaccc gtctgcgaaa atcactgaaa ttgtggcagg tggtgatgat
    81781 gggtctggcc tatctcacgc cgatgaccgt atttgatact tttggtattg tctccggcat
    81841 tagcgacggt cacgttccgg cgtcctattt gctggcgctg gcgggtgtgc tgtttaccgc
    81901 tatcagctac ggcaaactgg ttcgccagtt tccggaggcc ggttcggcct atacctacgc
    81961 gcaaaagtcg attaacccgc acgtcggatt tatggtcggc tggtcatcgc tgctggatta
    82021 tctctttttg ccgatgatta acgtcttgtt ggcgaaaatc tatctctccg ccctcttccc
    82081 ggaagtgccg ccgtgggtgt gggtggtaac cttcgtcgcc attttaaccg ccgcgaatct
    82141 gaagagcgtc aacctggtcg ctaacttcaa taccctgttt gtactggtgc aaatctccat
    82201 catggtggtg tttatcttcc tggtagttca gggactgcat aaaggagaag gcgttggcac
    82261 cgtctggtca cttcagccgt ttatcagcga gaacgcgcac ctgatcccga ttattaccgg
    82321 ggcgacgatt gtctgtttct ccttcctcgg tttcgatgcg gtgaccacgc tttcggaaga
    82381 gacgccggac gccgcacgcg tgatcccgaa agccatcttc ctgacggcgg tctacggtgg
    82441 cgttatcttt atcgcggcgt cgttctttat gcagctgttc tttcccgata tcagccgctt
    82501 taaagatccg gatgccgcac tgcctgaaat tgcgctgtac gtcggcggca agctcttcca
    82561 gtcgattttc ctctgcacca cgtttgtgaa caccttagcc tctggcctgg cttcacatgc
    82621 cagcgtgtcg cgtctgctgt atgtgatggg gcgtgacaat gtgtttccgg agcgcgtgtt
    82681 tggctatgtg cacccaaaat ggcggactcc ggcactcaac gtcattatgg tcgggattgt
    82741 cgcgttgtcg gcgctgttct tcgatttagt taccgccaca gcgttaatta acttcggtgc
    82801 tctggtggcg tttaccttcg tgaatctgtc ggtgtttaat catttctggc ggcgtaaagg
    82861 aatgaataaa agctggaagg atcacttcca ctatttgctg atgccgctgg ttggcgcgct
    82921 gacggtgggt gtgctgtggg ttaacctcga gtcaacgtca ctgacactcg gtctggtatg
    82981 ggcttcgtta ggcggcgcat atttatggta tctgatccgc cgctatcgca aagtgccgtt
    83041 gtatgatggt gacagaacgc cggtgagtga aacgtaatag tcggatgcgc ggcgcattat
    83101 cctgcctgag ggtaacgcgc cgcgccatta actataaaaa gatgtatgac ccggatcacg
    83161 agtgctatca tccgccctta tgcttagcgc attaacccca ggggcaaata atgaaccacg
    83221 atatcccgct aaaatatttt gatattgccg atgagtacgc gaccgaatgc gcagagcctg
    83281 tcgcagaggc tgaacgcaca ccgctggccc actacttcca gttactgctc acccgtttga
    83341 tgaacaatga agagatcagc gaagaagccc aacatgaaat ggctgctgaa gcggggatta
    83401 atcccgtacg cattgatgag atcgcagagt ttttgaatca atggggtaat gagtaatgat
    83461 ttaattgcag acgatcggtc agtatcgttg tccggataaa gcgttcacgc cgcatctggc
    83521 taacaatgac acgcactgca gcgtgcttta atgggtttct cacgatcgta ccgctctgct
    83581 cctcgctaag ttgttctgtg agttatagtt atagagaaat cacgggtacg aatgttgaac
    83641 agatggcgac gtcacctgtt caacgaccaa ccacacggcc ctcattacga cccctgaaca
    83701 caaacggtaa tggcaaatgt cattaaatat tagtaagata gcctctttac ataaaatccc
    83761 ttaatattat gcgccaggta ttatcgtctc ttttggtgat tgctggactt gtgagtggtc
    83821 aggcaatcgc cgcgcctgaa tctcccccgc atgctgatat ccgcgacagc ggttttgtct
    83881 attgcgtcag cgggcaagtc aacaccttta acccatccaa agcgagcagt gggttaattg
    83941 tcgataccct tgccgcccag ttttatgatc gactgctgga tgtcgatccc tatacctatc
    84001 gcctgatgcc ggaacttgcc gaaagctggg aagtactcga caacggcgcg acctatcgct
    84061 tccacctgcg tcgcgatgtt ccgtttcaaa aaaccgactg gtttactccc actcgtaaaa
    84121 tgaatgccga cgatgtggtg tttaccttcc agcgaatttt tgaccgcaac aacccgtggc
    84181 ataacgtcaa cggcagcaac ttcccctact tcgacagcct gcaatttgcc gataacgtga
    84241 aaagcgtccg caaactggat aatcataccg ttgagttccg actcgcccag ccggatgctt
    84301 cttttttgtg gcacctcgca acccattatg cttcggtcat gtcggcagaa tatgcccgga
    84361 agttagagaa agaagatcgc caggagcaac tcgaccgtca accggtcggc accggtccgt
    84421 atcagttgtc ggaataccgc gccgggcaat ttattcgcct acaacgtcat gatgacttct
    84481 ggcgcggtaa accgttaatg ccgcaggtag tggtggattt aggctccggc ggcaccggac
    84541 gtctgtcgaa actcctgacc ggggaatgcg acgttctggc ctggcctgct gccagccagc
    84601 tatccatttt gcgtgacgac ccgcgcttgc gtttaacgct gcgtcctggg atgaacgtcg
    84661 cctatctggc atttaacacc gccaaaccgc cgctaaataa tcccgctgtc cgccatgcgc
    84721 tggcactggc gattaataac cagcgcctga tgcaatccat ctattatggt acggctgaaa
    84781 cggcggcctc tattttaccg cgcgcctcgt gggcctatga caacgaggct aaaattactg
    84841 aatacaatcc ggcgaaatcg cgcgaacagt tgaagtcgtt ggggctggaa aatttaacgc
    84901 tgaaactgtg ggtgcccaca cgttcgcagg cgtggaaccc cagtccactg aaaactgccg
    84961 aactgattca ggcggatatg gcgcaggttg gcgtaaaagt ggtgattgtg ccggtagaag
    85021 gtcgctttca ggaggcgcgg ttgatggata tgagccatga tctgacgtta tccggttggg
    85081 cgacggacag taacgacccg gacagtttct tccgtccgtt actgagctgc gcggcaattc
    85141 attcgcagac caacctcgcc cactggtgcg atccgaaatt cgacagcgta ttgcgtaagg
    85201 cgctctcttc gcagcagctg gcggcgcgta ttgaagccta tgacgaagcg cagagtattc
    85261 tggcgcagga attgcccatt ttgccgctgg cgtcgtcatt gcgtttgcag gcctatcggt
    85321 acgatatcaa aggtctggta cttagcccgt ttggtaacgc ctcctttgct ggggtgtatc
    85381 gcgagaaaca ggatgaggtg aaaaaaccat gattatcttc accttacgcc gcattttgtt
    85441 attgattgtc accttgttcc tgctgacctt cgttggcttc agcttgagct atttcacccc
    85501 tcatgcgccg ttacaaggcg cgtcactgtg gaatgcctgg gtgttctggt ttaacggcct
    85561 gatccactgg gattttggtg tttccagcat taacggtcaa ccgattgccg aacagttaaa
    85621 agaggtcttc ccggcgacga tggaactgtg catcctcgcc ttcggttttg cgctgattgt
    85681 tggcatcccc gtggggatga ttgccgggat tacgcgccat aagtggcagg ataacttgat
    85741 caacgccatc gccttactgg gcttttcaat cccggtgttc tggctggcgc ttctgttgac
    85801 gctgttttgt tcactcacgc taggttggtt gcccgtttca gggcgtttcg atctgctcta
    85861 cgaagtgaaa ccgattaccg gttttgcgtt gattgatgcc tggctttcgg actcaccatg
    85921 gcgggatgaa atgatcatga gcgcaatccg ccatatgata ttgcccgtga tcaccctgtc
    85981 ggttgcgcca acaactgaag tgatccgcct gatgcgtatc agcactatcg aagtgtatga
    86041 ccagaactat gtaaaagcgg cggcgacccg cggtttgtcg cgctttacta ttttgcgtcg
    86101 ccacgttctg cataacgcgt taccgccggt tattcctcgc ctgggcttac agttttccac
    86161 catgctgacg ctggcgatga tcaccgaaat ggtttttagc tggccgggtt tagggcgctg
    86221 gttaattaac gccatccgcc agcaggatta cgcagccatt tccgccggag tgatggtgtg
    86281 tggctcactg gtcattattg ttaacgtgat ttctgatatt ttgggtgcca tggctaaccc
    86341 tctgaaacat aaggaatggt atgccttacg atagcgtata cagcgaaaag cgcccgccgg
    86401 gcacgctgcg taccgcctgg cgcaaatttt atagtgacgc ctctgcgatg gtcggcctgt
    86461 acggctgcgc ggggctggct gtactgtgta tttttggcgg ctggtttgcg ccttacggca
    86521 tcgaccagca atttctcggt tatcaattat tgccgccgtc atggtcgcgc tatggcgaag
    86581 tttctttctt cctggggact gacgacctcg gacgcgatgt tttaagccgt ttactgagcg
    86641 gagctgcgcc aaccgtgggt ggcgcatttg tggtgacgct tgccgcgacg atctgtggcc
    86701 tggtactggg caccttcgcc ggggcgacac acggcctccg ctcagcggtg cttaaccata
    86761 ttctggatac cttactggcg atcccttcgc tgctgttggc aattatcgtt gtagcgtttg
    86821 ccggaccgag tttgtcccac gctatgtttg ctgtctggct ggcattgctg ccgcgtatgg
    86881 tacgttcgat ttacagcatg gtgcatgacg aactggaaaa agagtacgtt atcgccgccc
    86941 gtctggatgg cgcatcaacg ctgaatattc tctggtttgc tgtgatgcca aacatcaccg
    87001 ccgggctggt caccgagatc acccgcgcac tgtcgatggc aattctcgat atcgccgcgc
    87061 tgggctttct cgatctcggc gcacaactcc cctcgcctga atggggagcg atgctcggtg
    87121 atgcgctgga actgatttat gtcgccccgt ggactgtcat gctgccaggt gcggcaatta
    87181 tgattagcgt gttgttggtt aacctccttg gcgatggcgt tcgtcgtgcg attattgcgg
    87241 gggtggaata atgccattac tcgatattcg taacctgacc attgaattta aaaccggtga
    87301 tgagtgggtt aaagccgtcg accgggtaag tatgacctta accgaaggtg aaatccgcgg
    87361 tcttgttggt gaatccggtt ccggcaagag tttgattgcg aaagcgattt gtggggtgaa
    87421 taaagataac tggcgtgtta ctgctgaccg tatgcgtttt gatgatatcg atttgctgcg
    87481 tctctccgca cgcgaacggc gcaaactggt tggccataac gtgtcgatga ttttccagga
    87541 accgcagtcg tgtcttgacc cttcagaacg tgtgggccgc cagttgatgc aaaacatccc
    87601 agcctggacc tataaaggcc gttggtggca gcgttttggc tggcgcaaac gccgtgccat
    87661 tgaactgctg caccgcgtgg ggattaaaga tcacaaagat gcgatgcgca gttttcccta
    87721 tgagttgacc gaaggtgaat gtcagaaagt gatgatagcc attgcactgg cgaatcaacc
    87781 gcgtctgctg attgctgacg aaccgaccaa ctcaatggag ccaacaaccc aggcgcaaat
    87841 ctttcgcctg ctgacgcgtc tcaaccaaaa cagcaatacc actattttgc ttatcagcca
    87901 tgacttacaa atgcttagcc aatgggcgga taaaattaac gtgctttact gcggtcaaac
    87961 agtggaaacc gcgccgagta aggagttggt gacgatgcca catcatcctt atacccaggc
    88021 gctgatccgc gcgataccag acttcggcag cgcgatgccg cataaaagtc gcctcaatac
    88081 gctgcccggc gctatcccac tgctggaaca gttaccgatt ggttgtcgtc tggggccacg
    88141 ttgcccgtat gcacaacgag aatgcattgt gacgccacgt ttgacggggg cgaaaaatca
    88201 tctctatgcc tgtcatttcc cgctgaacat ggagaaagag tgagatgatc gaaacgctgc
    88261 ttgaagtgcg taatttaagt aaaacgttcc gctaccggac cggctggttt cgtcgtcaga
    88321 ccgtagaagc ggtaaaaccc ttgagcttta cgctacgtga aggccagaca ctggcgatta
    88381 ttggcgagaa tggttcgggt aaatccacgc tggcaaaaat gctggcggga atgatagagc
    88441 ctaccagcgg cgagttattg attgacgatc atccactgca ttttggcgat tattccttcc
    88501 gcagtcagcg tattcgcatg atttttcagg atccttcgac ctcgttgaat ccccgtcaac
    88561 gtatctcgca aattctggat tttccactgc gcctgaacac cgacctggaa ccggaacagc
    88621 gtcgcaaaca gattattgaa acgatgcgta tggttgggct gctaccggat cacgtcagtt
    88681 actatccgca tatgttggca cccggacaaa aacagcgtct gggtctggcg cgcgcgctga
    88741 tattgcgccc aaaagtcatt attgccgatg aagccctcgc ttcactggat atgtcgatgc
    88801 gttcgcagtt gattaatctg atgctggaat tacaggaaaa acagggcatt tcgtatattt
    88861 atgttaccca gcatatcgga atgatgaagc acattagcga ccaggtgctg gtgatgcatc
    88921 agggcgaggt tgtcgagcga ggcagcaccg cggatgtgct ggcatcgccg ctgcatgaac
    88981 tcaccaaacg gctgattgcc ggtcattttg gcgaggcatt gacggcggat gcgtggcgta
    89041 aagatcgcta attttctgaa tcctccttcc agattattca cctcattctg acaaaagatt
    89101 aaatcttgtc agaatgaggt gatagataaa attaaatcaa atgcgcgtga tttaagacgc
    89161 aatctcactt tgcaggaacg aaagctctgg cgatatcttc gcagccgacg ttttagtgat
    89221 ttcaaatttc gccgtcaaca tccagtgggg agctacattc tcgattttgc ttgctgctcg
    89281 gcgcgtgtag tcgttgagct ggatggtggg cagcatgatt tagcagttgc ctatgattcc
    89341 aggcgcacta gctggcttga gtcgcagggc tggaccgtgc tgcgtttctg gaataacgag
    89401 attgattgta atgaggagac ggtgctggag aatattctgc aggaactgaa ccgccggtca
    89461 ccctctccct gaaagagcga gggggcagac cgagccgaat agctgttgtg gtgaaaacat
    89521 ggagacggtg ctggagaata ttcggcaagg tctgaaccgt cccagccatc gccatgaaag
    89581 ggttaggggc tgtatgagcc tgtttgttgc tggggtaaca atatttgcac aatacggtcc
    89641 cctcgcccct ctggggagag ggttagggtg aggggaaaag cgccccccct gccgcagcct
    89701 gctccggtcg gacctggcaa ctatagctac tcacagccag gttgattata ataaccgttt
    89761 atctgttcgt actgtttact aaaacgacga atcgcctgat tttcaggcac aacaagcatc
    89821 aacaataagg attaaagcta tgggttttct ttccggtaag cgcattctgg taaccggtgt
    89881 tgccagcaaa ctatccatcg cctacggtat cgctcaggcg atgcaccgcg aaggagctga
    89941 actggcattc acctaccaga acgacaaact gaaaggccgc gtagaagaat ttgccgctca
    90001 attgggttct gacatcgttc tgcagtgcga tgttgcagaa gatgccagca tcgacaccat
    90061 gttcgctgaa ctggggaaag tttggccgaa atttgacggt ttcgtacact ctattggttt
    90121 tgcacctggc gatcagctgg atggtgacta tgttaacgcc gttacccgtg aaggcttcaa
    90181 aattgcccac gacatcagct cctacagctt cgttgcaatg gcaaaagctt gccgctccat
    90241 gctgaatccg ggttctgccc tgctgaccct ttcctacctt ggcgctgagc gcgctatccc
    90301 gaactacaac gttatgggtc tggcaaaagc gtctctggaa gcgaacgtgc gctatatggc
    90361 gaacgcgatg ggtccggaag gtgtgcgtgt taacgccatc tctgctggtc cgatccgtac
    90421 tctggcggcc tccggtatca aagacttccg caaaatgctg gctcattgcg aagccgttac
    90481 cccgattcgc cgtaccgtta ctattgaaga tgtgggtaac tctgcggcat tcctgtgctc
    90541 cgatctctct gccggtatct ccggtgaagt ggtccacgtt gacggcggtt tcagcattgc
    90601 tgcaatgaac gaactcgaac tgaaataatc gttctgttgg taaagatggg cggcgttctg
    90661 ccgcccgtta tctctgttat acctttctga tatttgttat cgccgatccg tctttctccc
    90721 cttcccgcct tgcgtcagga taacgatttc ctttacgacc aaggagcgcc catggaacaa
    90781 cgccacatca ccggcaaaag ccactggtat catgaaacgc aatccagtac tacggagtat
    90841 gacgttctgc ctctggtccc ggaagccgca aaggtcagcg atccctttct actcgacgtg
    90901 atccttgaaa aagaaacgct ggcccccttc ctttcatggc tggaccctgc gcgtgttctt
    90961 gcagtggatt tgttccctga ccagcttacc gtgacccgtt cacagacctt caccgcttat
    91021 gaacgcttgt cgacggccct gacggttgct caggtttgcg gcgtccagcg gttatgtaac
    91081 tactattcgg cgcgacttac gccgctcccc gggcctgatt ccaccaggga aagtaatcat
    91141 cggttggcac aaatcacgca atatgcccgc caactggcta gctcgccttc tattatcgac
    91201 aaccgatcgc gccagcatct gaatgacgtc ggtcttactg cctgggactg tgtgatcatt
    91261 agccaaatca ttggttttat tggctttcag gcgcggacaa ttgcgacatt tcaggcttat
    91321 ctcgggcatc cggtacgctg gttacccggg ctggagatac aaaactacgc cgacgcgtca
    91381 ctgtttgctg atgaatcatt acgctggcga agcagctatg aggtggaaaa actacctgaa
    91441 gagcacacaa aaagttcaac tgcagaactt tgccaactgg ccgaaatact ctctctccac
    91501 cctatttcac tttcccttct cgaaaagttg ttaaacagca cacggggcaa tacacagccg
    91561 gataatcagc ttgcggcgtt gttatgcgcg cgtataaatg gcagtcctgc ttgttttgcc
    91621 acctgtatgg attcatcaaa tgaatataaa aaaatcagca cccttatgcg caagggcgaa
    91681 aatgaaatta accaatgggc tgaccgtcat tctgttgagc gcgctaccgt tcaggcgata
    91741 caatggctga cccgagcacc cgatcgcttt agcgccgccc agttcagccc tttactcgaa
    91801 cacgaaaaat catcaacgca gattattaat ctgctggtat ggagcgggct gtgtggctgg
    91861 ataaatcgct taaaaatcgc gttgggtgag acatattaac cttgccgcgt cagacagatt
    91921 cgcgtaaaac tgtcagccgc tctaatggcc accaaaatag acaattatgt ttcaggacaa
    91981 cccgctgcta gcgcagctta aacagcaact gcattcccag acgccacgcg ctgaaggggt
    92041 ggtaaaagcc acagaaaaag gctttggctt cctggaagtc gacgcgcaaa aaagttattt
    92101 cattccgccg ccgcagatga aaaaagtcat gcatggcgac cgaattatcg cggtgatcca
    92161 cagtgaaaaa gaacgtgaat ccgcagagcc agaagaactg gttgaaccgt tcctgactcg
    92221 tttcgtgggt aaggttcagg gcaaaaatga ccgtctggcc atcgttcctg atcatccact
    92281 cttaaaagac gccattcctt gccgcgcagc ccgtggcctg aaccacgagt ttaaagaagg
    92341 cgactgggcg gttgccgaaa tgcgccgtca tccgctgaaa ggcgatcgtt ctttctatgc
    92401 agaactgaca caatacatca cttttggtga cgatcacttt gtaccgtggt gggttaccct
    92461 tgcacgccat aatctggaaa aagaagcacc agacggcgtc gctaccgaaa tgctcgatga
    92521 aggtctggtt cgtgaagatc tgaccgcgct ggattttgtc accatcgaca gtgccagcac
    92581 agaagatatg gatgacgccc ttttcgctaa ggcgttgccg gatgacaaac ttcagctgat
    92641 tgtggcgatt gccgatccaa ccgcgtggat tgctgaaggc agcaagctgg acaaagccgc
    92701 gaaaattcgc gcattcacca actatctgcc tggcttcaac atccctatgc tgcctcgcga
    92761 gctttctgac gatctctgct cactgcgcgc caatgaagtc cgcccggtac tggcatgccg
    92821 catgacgctc tccgctgatg gcaccattga agataatatc gaattctttg ccgccaccat
    92881 cgaatccaaa gcaaagctgg tgtatgacca ggtttctgac tggctggaaa ataccggtga
    92941 ctggcagcct gaaagtgaag caattgccga acaagtccgt ttgctagcgc aaatttgcca
    93001 acgccgcggc gagtggcgtc ataaccacgc actggtgttt aaagatcgcc cggattaccg
    93061 ctttattctc ggtgaaaaag gtgaagtgct ggatatcgtc gccgagcctc gtcgcattgc
    93121 caaccgtatc gtcgaagaag cgatgattgc cgctaacatt tgtgcggccc gcgtactgcg
    93181 cgataagctc ggttttggca tctataacgt gcatatgggc tttgatccgg cgaatgccga
    93241 cgcgctggca gcgttgctga aaacgcacgg tctgcatgtc gatgccgaag aagtgctcac
    93301 gctggacggt ttctgcaaac tgcgtcgtga actggacgcg caaccaactg gtttcctcga
    93361 cagccgcatt cgtcgcttcc agtcatttgc tgaaattagc actgaacccg gtcctcactt
    93421 tggcctcggt ctggaagcat acgccacctg gacttcgccg atccgtaaat atggcgacat
    93481 gatcaaccac cgtctgctga aagcggttat caaaggcgaa actgcgacgc gcccacagga
    93541 tgaaatcact gtccaaatgg ccgagcgtcg ccgtctcaac cggatggcag aacgtgatgt
    93601 tggtgactgg ttatacgcac gcttcctgaa agacaaagcc gggaccgaca cccgtttcgc
    93661 agcggaaatt gtcgatatca gccgtggcgg catgcgtgtt cgtttggttg ataacggcgc
    93721 tatcgccttt attccggcac ctttcttaca cgctgtgcgc gatgaactgg tttgcagcca
    93781 ggaaaacggc actgtacaaa ttaaaggtga aacggtttac aaagtgactg acgttattga
    93841 cgtcactatt gccgaagtcc gcatggaaac ccgcagcatt attgcgcgcc cggtcgcgta
    93901 atctcctttc acggcccatt cctcatggat gggccgttta tttccccgct ctaccttcgt
    93961 tatatccagg cagatttttt aactgacttt cgtttgaaaa ctggcgtttt tccaaaactg
    94021 gattacaaat aaatatataa aaaaaacaat gcgtttagcc gccgttaatt tcatgtaagt
    94081 catgttgttc cttttattta accgcggact ccgctgttaa ccggaggata tgcatcatga
    94141 aaaccgttag ggagtccaca acgttgtaca actttctcgg atcgcacaat ccatactggc
    94201 ggttgacgga aagcagcgat gttttgcgct tttctaccac cgaaaccaca gaacctgatc
    94261 gtacattgca gttatctgcc gaacaggctg ctcgcatcag ggaaatgacg gtcatcacct
    94321 ccagcctgat gatgagtctg accgtcgatg aaagcgatct ttctgtgcat ctggtaggac
    94381 gaaaaatcaa taaacgggaa tgggctggca acgcgtctgc atggcatgac acaccggcgg
    94441 ttgctcgtga tttatcacac gggctttcct ttgctgagca ggtagtttct gaagcacatt
    94501 ccgcaatagt gattctcgac agccggggga atatccaacg cttcaatcgg ttatgtgaag
    94561 attacacagg gttgaaagaa cacgacgtca ttgggcaaag cgtgtttaaa ctgtttatga
    94621 gccgtcgtga agctgcggca tccaggcgca ataaccgtgt attttttcga agcggcaatg
    94681 catatgaagt cgaactgtgg ataccaacat gtaaaggcca gcggctgttt ctgtttcgca
    94741 ataaatttgt ccacagcggc agtggcaaaa acgagatttt tttaatctgt tccggcaccg
    94801 acattaccga agagcgccgc gctcaggagc gactgcgtat tctggcaaat accgacagta
    94861 tcaccggact gccgaatcgt aacgcaatgc aggatttaat cgatcacgct attaatcatg
    94921 cagataacaa taaagttggg gttgtgtatc ttgatttgga taatttcaaa aaggtcaacg
    94981 acgcctatgg gcatttgttt ggtgaccagt tattacgcga cgtgtcattg gctattttaa
    95041 gctgtctcga acatgaccag gtgttggcgc gtccaggtgg ggatgagttt ctggtactgg
    95101 catccaacac ctcacaaagc gcgctggaag caatggcatc acgaattttg acccgcttac
    95161 ggctcccctt tcgcattggt ttaattgaag tttataccag ctgttcagta ggtattgcac
    95221 tctctcccga acatggttca gacagcacgg ctattattcg tcacgccgac acagcaatgt
    95281 acacagcgaa ggaaggcgga cgaggacaat tttgcgtttt taccccagaa atgaatcaac
    95341 gggtatttga atatctctgg ctggatacca acttgcgtaa agcactggaa aacgatcagt
    95401 tggttattca ctatcaaccg aaaatcacct ggcgtggcga agtgcgcagt ctggaagcac
    95461 tagtacgttg gcagtcacct gaacgtgggt tgattccacc gttggacttc atttcctacg
    95521 ccgaagagtc agggctaatt gtgcctttag gccgttgggt gattctcgat gtcgtacgcc
    95581 aggtggcaaa gtggcgggat aaaggcataa acctgcgagt ggcggtaaat atttctgcac
    95641 gtcagctcgc cgatcaaacc attttcaccg ccctgaaaca ggttctccag gaactcaatt
    95701 ttgaatactg ccctatagat gttgaactga cagagagttg tctgattgag aatgatgaac
    95761 tggcactgtc tgttattcaa caatttagcc aactaggtgc gcaagtgcat ctggatgatt
    95821 ttggtaccgg ctactcttca ctttcgcaac tggcgcgctt tccgatcgat gccatcaaac
    95881 ttgaccaggt ttttgttcga gatattcaca aacaacctgt ctcgcagtca ctggtccggg
    95941 cgatcgtcgc tgtggcccag gcattgaatc ttcaggtgat cgccgaaggt gtagagagtg
    96001 caaaggaaga tgctttttta accaagaacg ggatcaatga gcggcaagga tttttgtttg
    96061 ccaaaccgat gcccgccgtc gccttcgaac gctggtataa acgctatctg aagcgcgcat
    96121 aagtagatga atatatatac ttagcgctat atcccgtcat tatatatcgt attcctggat
    96181 gataattagc cgttgctgtt aaacacttct cttttagcgg caatttttgc attattcatt
    96241 ttcccccttt tgctataagg atgtccttga tgtctgaatt tgatgcccag cgcgttgccg
    96301 aacgtattga tattgtgtta gatatccttg tggcaggcga ttaccactct gcgatccata
    96361 atctcgagat acttaaagca gaactcttgc gccaggttgc tgaatctacg ccagacatcc
    96421 cgaaggcacc gtgggagatt taacaatcgt gccttcaggt tttcctattt gaggatgccc
    96481 ggcgcgtcag tattttttta ttaagtatta taacgttata agaattacag cgatgaattc
    96541 ccgacaacaa actattctac agatggtcat tgaccagggt caggttagcg taaccgatct
    96601 ggcaaaagcc actggagttt ctgaagttac cattcgccag gatctcaaca cactcgaaaa
    96661 actgagttac ctccgccgtg cacatggctt tgctgtttcg cttgatagtg atgacgtcga
    96721 aacccgtatg atgagcaact atacgctgaa gcgtgaactc gccgagtttg ccgcgtcgct
    96781 ggttcaaccg ggcgaaacca tctttatcga aaatggcagc agcaatgccc tactcgcccg
    96841 gactctgggc gagcagaaga aaaatgtcac tatcatcacg gtcagcagct acatcgcgca
    96901 tttgctgaaa gacgcgcctt gtgaagttat tttgctcggt ggcgtgtatc agaaaaaaag
    96961 cgaaagtatg gttggccctt tgacacgcca gtgcatccaa caggtgcatt tcagcaaagc
    97021 atttattggt attgatggct ggcaacctga aactggattt accggtcgcg atatgatgcg
    97081 taccgatgtg gtcaatgccg tgctggaaaa agagtgcgaa gcgatagtcc tgactgacag
    97141 ctcgaaattt ggtgctgtac attcatactc catcggtccc gttgagcgat tcaatcgcgt
    97201 gattaccgat tcgaaaatac gcgccagcga tctgatgcat cttgagcaca gtaaactcac
    97261 cgttcacgtc gttgacattt aaccatttcc cttctctacg gatgatttgc agtttggcaa
    97321 atcatccgct ctaagatgat tcctggttga taattaagac tatttacctg ttattaacac
    97381 tctcaagata taaaattatt atcagcgata taacaggaag tcattatcac ctgcgtgata
    97441 taaccctgcg cgcgagcaga tttcacggaa taatttcacc aggcttattc ttagctatta
    97501 tagttataga gagcttactt ccgtgaatca taaattcagg agagagtatt atgtttgtaa
    97561 cgagcaaaaa aatgaccgcg gctgttctgg caattacttt ggcaatgtct ctgagtgcct
    97621 gttctaactg gtctaaacgg gaccgcaaca ccgcaatcgg cgcgggtgca ggggcattag
    97681 gcggtgcagt actgaccgat ggcagtacgt tgggtacatt aggtggtgca gctgtcggtg
    97741 gtgttattgg tcaccaggtc ggtaaataat cgtaaataaa tgtcgattat cgactcgcaa
    97801 ttataatacg cttgattctg ttcagtacga aataactgaa taatacgcac agtaaaatat
    97861 tcgaaagcca cggatatatc cgtggctttt tatgttaacc gcctgcgagt tttaccttca
    97921 tccctttcgc ttcaagtagt gattttaata aatcacgctt atcgccctgg atttcaataa
    97981 ctccatcttt aactgctccg ccgcagccgc attttttctt cagttccgct gcaagttttg
    98041 tcagttcggc atcatcgaga tcgacaccgg taatcaggca aacgccctta cctttacgtc
    98101 cactggtctg acgctgaata cgcaccacac cgtcgccttt agggcgtaca ggggccgctt
    98161 tgggctcatc aatacgtccg gtttccgttg agtagaccag acggctgttg gaatcactca
    98221 tcatgcactc cgctgtaaag aggcgttgat cgctttcagc gtctgcgctg gatctaccga
    98281 ttgcgttacc gggcgaccaa tcaccatata atcaacacca gccgacaacg cctgttctgg
    98341 cgtcataatg cggcgctggt caccagcttc actcccctgc ggacgaatgc ccggcgtaac
    98401 cagtttgaac tcctgaccga atacctgttt aaagcgcaca gcttcctgag cagaacacac
    98461 cacaccatca aggccacatt tttgcgtcag tgccgccaga cgttctgcat aatctgcagg
    98521 tgacagtgtc atgccaagat cgaccaggtc gctggcttcc atgctggtca acactgtcac
    98581 agcaatcaaa agcggtgcat ctttgccaaa cggaaccagt gcctcacgcg ctgcggtcat
    98641 catacgcgcc ccaccagagg catgaacatt caccatccac acgcctaagt cagctgcagc
    98701 agcgacagcg tgcgctgcag tgttggggat atcgtggaat ttcaggtcaa gaaagatatc
    98761 aaaaccacgc tgttgaagtt cgcgcacaaa ctgtggccca aacaatgtaa acatctcttt
    98821 gccgaccttc agacgacaat cgcgtgggtc gatcttgtcg acaaaggcca gcgcgtcatc
    98881 acgattatga taatcaaggg caacaaccac aggagaattc gtaacagcgc gggaagaaga
    98941 tgaagcagtt aacgtcatga ccagaccttc ttgatgatgg gcaccggaag tggcgcgaaa
    99001 caggtaaacg gcgagcattc tacccgtgga aataaaaaat taacagttgc gatttctccc
    99061 ctggcaggct ttttctgcgc cgtcgttgcc ggagcacaat ggaacattaa taattagtat
    99121 gttgtaacta aagtcggatt ttttttaaaa attacaggcc atcaagaccg cgaatcggtt
    99181 taatggttga ccaggcccga caagacggac aatgccagta gagggtgtat gcggtaaaac
    99241 cacatttctg gcaacgataa cgaggcttac tacgtacctt ctcgccaacc atgtcacgca
    99301 gcaccatcag gctctctttg gcacgccctt cttccgcttc atttaagtgg taatccatta
    99361 acttatggaa cacacgcatg gtcggatgac gctgaagctg gcgcgtaata tagacctgtg
    99421 cggcctcact accgtcgcgc gcttcgatga tatcagcaag catcaattca gcatcggcac
    99481 cggtgttctc ttccaccgca cgctgcagga attctgccca ttcggcagtt ttacccaact
    99541 gctgatagca ggtttgcaac atttccagcg tttcgctgac cagttctctg tcctgggata
    99601 tcacgcgttg cagactttcg acggctttgg cgtattctcc tttcgccata aacacgcgtc
    99661 ccatcattat ggatacgcgg gcgctgtttt tatctgccgc cgcccctttt tttagcaagg
    99721 tcatggcacg atcgagatcg tcgctggcca tatgctgcag ggctaactca cagtagaaat
    99781 gggcaatttc gacgcgctgt ttatctttac ccagcttcac caggcgttcg gcaacatcaa
    99841 ttgctttctg ccactcactg gtagcctggt agatttgtag caactgttgc agcgcgccaa
    99901 tgcggaagtc agtttcatcg gtcagctgat tgaacatgtc ttccgcgcgg tcatataacc
    99961 cggcggccat gtaatcacgc cccagttgtt gaatcgccaa cagacgctgt tcataggtca
   100021 gcgaggcgct ttccattagg gtctgatgga tgcgaatagc gcgatcaact tcgccacgcg
   100081 aacggaacag gtttccgagc gtaaggtggg cttcaacggt gcctgtatcc tctttaagca
   100141 tatcgagaaa caggtctacc gctttatcct gttgattact aagcaggaag ttaacccccg
   100201 ctacgtaatc acgcgacaag cggttggctt catcttgctt gttttgttgc gcacttctg
//
LOCUS       DACAOP010000002        94315 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.002, whole genome shotgun sequence.
ACCESSION   DACAOP010000002 DACAOP010000000
VERSION     DACAOP010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 94315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94315
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.002"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..279)
                     /gene="tdcR"
                     /locus_tag="IT892_000096"
     CDS             complement(<1..279)
                     /gene="tdcR"
                     /locus_tag="IT892_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TdcR"
                     /protein_id="HAP3133352.1"
                     /translation="MTGITIFYGDNIIRYVVNTKKGLRPYFKQLPDNYQANFELNLMS
                     KFSNFIINKSFSAINNAARHIFSRYLLENKHLFYQYFKISNTGIDHLEQ"
     gene            469..1407
                     /gene="tdcA"
                     /locus_tag="IT892_000097"
     CDS             469..1407
                     /gene="tdcA"
                     /locus_tag="IT892_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TdcA"
                     /protein_id="HAP3133353.1"
                     /translation="MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIIND
                     IEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFG
                     FPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKL
                     QDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNG
                     ISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAV
                     WSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG"
     gene            1506..2495
                     /gene="tdcB"
                     /locus_tag="IT892_000098"
     CDS             1506..2495
                     /gene="tdcB"
                     /locus_tag="IT892_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HAP3133354.1"
                     /translation="MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEI
                     FLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGK
                     VVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIA
                     GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAA
                     SFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQR
                     NKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA"
     gene            2517..3848
                     /gene="tdcC"
                     /locus_tag="IT892_000099"
     CDS             2517..3848
                     /gene="tdcC"
                     /locus_tag="IT892_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine transporter TdcC"
                     /protein_id="HAP3133355.1"
                     /translation="MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRA
                     GFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITF
                     LYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLM
                     VKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIM
                     VFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLF
                     TLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGH
                     YLGTLEGLNGLILKFGYKGDKTKVSLGKLNTLSMIFIMGSTWVVAYANPNILDLIEAM
                     GAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF"
     gene            3874..5082
                     /gene="tdcD"
                     /locus_tag="IT892_000100"
     CDS             3874..5082
                     /gene="tdcD"
                     /locus_tag="IT892_000100"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417585.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HAP3133356.1"
                     /translation="MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAF
                     LSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITD
                     EVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
                     WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQS
                     VDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLS
                     SDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLI
                     RRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHL
                     GKVNAPAEFA"
     gene            5116..7410
                     /gene="tdcE"
                     /locus_tag="IT892_000101"
     CDS             5116..7410
                     /gene="tdcE"
                     /locus_tag="IT892_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-ketobutyrate formate-lyase/pyruvate
                     formate-lyase"
                     /protein_id="HAP3133357.1"
                     /translation="MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGD
                     ESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIV
                     GLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPD
                     MLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGIRYLVRERELQFADLQSRLEKGEDL
                     EATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNG
                     GAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSG
                     DPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYA
                     AQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYA
                     INGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDK
                     YSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDG
                     EYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNT
                     PDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKE
                     DPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGY
                     AVRFNALTREQQQDVISRTFTQAL"
     gene            7424..7813
                     /locus_tag="IT892_000102"
     CDS             7424..7813
                     /locus_tag="IT892_000102"
                     /EC_number="3.5.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enamine/imine deaminase"
                     /protein_id="HAP3133358.1"
                     /translation="MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPA
                     DVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATY
                     PTRSCVQVARLPKDVKLEIEAIAVRSA"
     gene            7885..9249
                     /gene="tdcG"
                     /locus_tag="IT892_000103"
     CDS             7885..9249
                     /gene="tdcG"
                     /locus_tag="IT892_000103"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HAP3133359.1"
                     /translation="MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSH
                     IVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGA
                     HIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLS
                     HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHD
                     GIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISG
                     AEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPC
                     IERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIK
                     VVCG"
     gene            9524..10855
                     /locus_tag="IT892_000104"
     CDS             9524..10855
                     /locus_tag="IT892_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026203.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HAP3133360.1"
                     /translation="MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMS
                     IGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSV
                     ISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGL
                     VLICILVAISSRGEKLLFKISTDMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLV
                     KNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFF
                     YAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTTFFG
                     VYLGFREATQGIVMNILRRKIPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTS
                     ICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS"
     gene            10883..12193
                     /locus_tag="IT892_000105"
     CDS             10883..12193
                     /locus_tag="IT892_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HAP3133361.1"
                     /translation="MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAEL
                     EGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQ
                     AIADAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNG
                     VVFTQQACVTEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEG
                     LSGNWGLHIGATLEKQCARGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQ
                     GITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAA
                     GMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDT
                     AVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR"
     gene            complement(12326..12490)
                     /locus_tag="IT892_000106"
     CDS             complement(12326..12490)
                     /locus_tag="IT892_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312016.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133362.1"
                     /translation="MSKKSAKKRQPVKPVVAKEPARTANNFGYEEMLSELEAIVADAE
                     TRLAEDEATA"
     gene            complement(12513..13214)
                     /locus_tag="IT892_000107"
     CDS             complement(12513..13214)
                     /locus_tag="IT892_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HAP3133363.1"
                     /translation="MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLN
                     QEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQTSTGEVLLLSTQPGVSYS
                     EHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMSKQQLIASPEGGMGSLQLRQQVW
                     LHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHYEEKAALTCGDGAFIRDEANITL
                     VADSPLRALLIDLPV"
     gene            13319..14215
                     /locus_tag="IT892_000108"
     CDS             13319..14215
                     /locus_tag="IT892_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3133364.1"
                     /translation="MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQK
                     LEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIV
                     TEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSS
                     EINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLD
                     KQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWR
                     RDSMGEAKSWCLREIPKLFSGK"
     gene            complement(14266..14622)
                     /locus_tag="IT892_000109"
     CDS             complement(14266..14622)
                     /locus_tag="IT892_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HAP3133365.1"
                     /translation="MQWYLSVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLIL
                     GLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEG
                     NSGSNRYGNDPKFGSN"
     gene            complement(14864..15229)
                     /locus_tag="IT892_000110"
     CDS             complement(14864..15229)
                     /locus_tag="IT892_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HAP3133366.1"
                     /translation="MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKML
                     GWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFN
                     CQAGTPGENRFGPDPKLEP"
     gene            complement(15512..16498)
                     /locus_tag="IT892_000111"
     CDS             complement(15512..16498)
                     /locus_tag="IT892_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HAP3133367.1"
                     /translation="MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTG
                     TGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSF
                     PGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAF
                     DALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVVKVFESLA
                     RLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRD
                     IYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG"
     gene            complement(16568..17050)
                     /locus_tag="IT892_000112"
     CDS             complement(16568..17050)
                     /locus_tag="IT892_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HAP3133368.1"
                     /translation="MILSIDSNDANTAPLHKKTISSLSGAVESMMKKLEDVGVLVARI
                     LMPILFITAGWGKITGYAGTQQYMEAMGVPGFMLPLVILLEFGGGLAILFGFLTRTTA
                     LFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
                     "
     gene            complement(17147..17446)
                     /locus_tag="IT892_000113"
     CDS             complement(17147..17446)
                     /locus_tag="IT892_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133369.1"
                     /translation="MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWN
                     MLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGLWSAWRLVKTTLKQQQLRG"
     gene            complement(17436..17840)
                     /locus_tag="IT892_000114"
     CDS             complement(17436..17840)
                     /locus_tag="IT892_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133370.1"
                     /translation="MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEK
                     ANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIW
                     TLRKSRKSTLLRHTRHELANDRQLLEEESREQ"
     gene            complement(17843..18148)
                     /locus_tag="IT892_000115"
     CDS             complement(17843..18148)
                     /locus_tag="IT892_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HAP3133371.1"
                     /translation="MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAE
                     QALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR"
     gene            complement(18186..18554)
                     /locus_tag="IT892_000116"
     CDS             complement(18186..18554)
                     /locus_tag="IT892_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1090 domain-containing protein"
                     /protein_id="HAP3133372.1"
                     /translation="MKYRIALAVSLFALSAGSYATTLCQEKEQNILKEISYAEKHQNQ
                     NRIDGLNKALSEVRANCSDSQLRADHQKKIAKQKDEVAERQQDLTEAKQKGDADKIAK
                     RERKLAEAQEELKKLEARDY"
     gene            complement(18701..19084)
                     /gene="mzrA"
                     /locus_tag="IT892_000117"
     CDS             complement(18701..19084)
                     /gene="mzrA"
                     /locus_tag="IT892_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EnvZ/OmpR regulon moderator MzrA"
                     /protein_id="HAP3133373.1"
                     /translation="MQIPRMSLRQLAWSGAVLLLVGTLLLAWSAVRQQESTLAIRAVH
                     QGTTMPDGFSIWHHLDAHGIPFKSITPKNDTLLITFDSSDQSAAAKAVLDRTLPHGYI
                     IAQQDNNSQAMQWLTRLRDNSHRFG"
     gene            complement(19088..19750)
                     /locus_tag="IT892_000118"
     CDS             complement(19088..19750)
                     /locus_tag="IT892_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HAP3133374.1"
                     /translation="MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLP
                     AAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNW
                     LSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMS
                     GLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGN
                     RG"
     gene            complement(20095..20871)
                     /gene="exuR"
                     /locus_tag="IT892_000119"
     CDS             complement(20095..20871)
                     /gene="exuR"
                     /locus_tag="IT892_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ExuR"
                     /protein_id="HAP3133375.1"
                     /translation="MEITEPRRLYQQLAADLKERIEQGVYLVGDKLPAERFIADEKNV
                     SRTVVREAIIMLEVEGYVEVRKGSGIHVVSNQPRHQQAADNNMEFANYGPFELLQARQ
                     LIESNIAEFAATQVTKQDIMKLMAIQEQARGEQCFRDSEWDLQFHIQVALATQNSALA
                     AIVEKMWTQRSHNPYWKKLHEHIDARTVDNWCDDHDQILKALIRKDPHAAKLAMWQHL
                     ENTKIMLFNETSDDFEFNADRYLFAENPVVHLDTATSGSK"
     gene            complement(21001..22299)
                     /locus_tag="IT892_000120"
     CDS             complement(21001..22299)
                     /locus_tag="IT892_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708898.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3133376.1"
                     /translation="MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNIST
                     QQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLA
                     VARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVM
                     HSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVDTAKKM
                     SVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFA
                     DLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCI
                     GGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSP
                     LFAVLAVFDLLGALVIWTVLQNKPAIEVAQESHNDPAPQH"
     gene            22782..24194
                     /gene="uxaC"
                     /locus_tag="IT892_000121"
     CDS             22782..24194
                     /gene="uxaC"
                     /locus_tag="IT892_000121"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAP3133377.1"
                     /translation="MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAED
                     YRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYH
                     WTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
                     IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADL
                     QTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFK
                     TAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLL
                     SKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMER
                     QMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLG
                     EMVKNICFNNARDYFAIELN"
     gene            24209..25696
                     /locus_tag="IT892_000122"
     CDS             24209..25696
                     /locus_tag="IT892_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAP3133378.1"
                     /translation="MQYIKIHALDNVAVALADLAEGTEVSVDNQTVTLRQDVARGHKF
                     ALTDIAKGANVIKYGLPIGYALADIAAGEHVHAHNTRTNLSDLDQYRYQPDFQDLPAQ
                     AADREVQIYRRANGDVGVRNELWILPTVGCVNGIARQIQNRFLKETNNAEGTDGVFLF
                     SHTYGCSQLGDDHINTRTMLQNMVRHPNAGAVLVIGLGCENNQVAAFRETLGDIDPER
                     VHFMICQQQDDEIEAGIEHLHQLYNVMRNDKREPGKLSELKFGLECGGSDGLSGITAN
                     PMLGRFSDYVIANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIA
                     HDQPIYENPSPGNKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAP
                     GNDAVATSALAGAGCHMVLFSTGRGTPYGGFVPTVKIATNSELAAKKKHWIDFDAGQL
                     IHGKAMPQLLEEFIDTIVEFANGKQTCNERNDFRELAIFKSGVTL"
     gene            25779..26330
                     /locus_tag="IT892_000123"
     CDS             25779..26330
                     /locus_tag="IT892_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgjV family protein"
                     /protein_id="HAP3133379.1"
                     /translation="MTAYWLAQGVGVIAFLIGITTFFNRDERRFKKQLSVYSAVIGVH
                     FFLLGTYPAGASAILNAIRTLITLRTRSLWVMAIFIVLTGGIGLAKFHHPVELLPVIG
                     TIVSTWALFRCKGLTMRCVMWFSTCCWVIHNFWAGSIGGTMIEGSFLLMNGLNIIRFW
                     RMQKRGIDPFKVEKTPSAVDERG"
     gene            complement(26335..27579)
                     /gene="sstT"
                     /locus_tag="IT892_000124"
     CDS             complement(26335..27579)
                     /gene="sstT"
                     /locus_tag="IT892_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAP3133380.1"
                     /translation="MTTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVG
                     LLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVF
                     SFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLG
                     FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQL
                     LVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMA
                     LCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVA
                     SLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTD
                     VLFTAAACQAEDDRLANSALRN"
     gene            complement(28195..29160)
                     /gene="alx"
                     /locus_tag="IT892_000125"
     CDS             complement(28195..29160)
                     /gene="alx"
                     /locus_tag="IT892_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family membrane protein Alx"
                     /protein_id="HAP3133381.1"
                     /translation="MNTVGTPLLWGGFAVVVAIMLAIDLLLQGRRGAHAMTMKQAAAW
                     SLVWVTLSLLFNAAFWWYLVQTEGRAVADPQALAFLTGYLIEKSLAVDNVFVWLMLFS
                     YFSVPAALQRRVLVYGVLGAIVLRTIMIFTGSWLISQFDWILYIFGAFLLFTGVKMAL
                     AHEDESGIGDKPLVRWLRGHLRMTDTIDNEHFFVRKNGLLYATPLMLVLILVELSDVI
                     FAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAERFSMLKYGLAVILVFI
                     GIKMLIVDFYHIPIAVSLGVVFGILVMTFIINAWVNYRHDKQRGE"
     gene            complement(29444..30430)
                     /locus_tag="IT892_000126"
     CDS             complement(29444..30430)
                     /locus_tag="IT892_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311996.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP3133382.1"
                     /translation="MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFAN
                     DFSVEHLFTSLEAMAESDAIDAVYIASPNALHFSQTQLFLSHKIHVICEKPLASNLAE
                     VDAAIACARENQVVLFEAFKTAYLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
                     DGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAHGVVVMD
                     YGDFSVTLQHSKVSDSVLASEIQGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHI
                     NTMLYEAELFAELVDEHLVDHPGLTVSRITAKLLTEIRRQTGVIFPADSVKL"
     gene            complement(30509..31201)
                     /locus_tag="IT892_000127"
     CDS             complement(30509..31201)
                     /locus_tag="IT892_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin high temperature exclusion protein"
                     /protein_id="HAP3133383.1"
                     /translation="MLRAFARLLLRICFSRRTLKIGCLLLLTAGATLFIADRVMVNTS
                     KQLTWSDVNAVPARNVGLLLGARPGNRYFTRRIDTAAALYHAGKVKWLLVSGDNGRKN
                     YDEASGMQQALIAKGVPAKVIFCDYAGFSTLDSVVRAKKVFGENHITIISQEFHNQRA
                     IWLAKQYGIDAIGFNAPDLNMKHGFYTQLREKLARVSAVIDAKILHRQPKYLGPSVMI
                     GPFSEHGCPAKE"
     gene            complement(31278..31781)
                     /locus_tag="IT892_000128"
     CDS             complement(31278..31781)
                     /locus_tag="IT892_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HAP3133384.1"
                     /translation="MSNLTYLQGYPDQLLSQVRTLINEQRLGDVLAKRYPGTHDYATD
                     KALWQYTQDLKNQFLRNAPPITKVMYDNKIHVLKNALGLHTAISRVQGGKLKAKAEIR
                     VATVFRNAPEPFLRMIVVHELAHLKEKEHNKAFYQLCCHMEPQYHQLEFDTRLWLTQL
                     SLGQDKI"
     gene            31866..33002
                     /gene="rlmG"
                     /locus_tag="IT892_000129"
     CDS             31866..33002
                     /gene="rlmG"
                     /locus_tag="IT892_000129"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(1835)-N(2))-methyltransferase
                     RlmG"
                     /protein_id="HAP3133385.1"
                     /translation="MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEI
                     RGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTAD
                     YPQQPGVVLIKVPKTLALLEQQLRALRKVVTPDTRIIAGAKARDIHTSTLELFEKVLG
                     PTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGAR
                     FFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNM
                     PEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKING
                     ELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR"
     gene            complement(33120..35138)
                     /locus_tag="IT892_000130"
     CDS             complement(33120..35138)
                     /locus_tag="IT892_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
                     /protein_id="HAP3133386.1"
                     /translation="MSYPSLFAPLDLGFTTLKNRVLMGSMHTGLEEYPDGAERLAAFY
                     AERARHGVALIVSGGIAPDLTGVGMEGGAMLNDASQIPHHRTITEAVHQEGGKIALQI
                     LHTGRYSYQPHLVAPSALQAPINRFVPHELSHEEILQLIDNFARCAQLAREAGYDGVE
                     VMGSEGYLINEFLTLRTNQRNDQWGGDYPNRMRFAVEVVRAVRERVGNDFIIIYRLSM
                     LDLVEGGGTFAETVELAQAIEAAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKL
                     KGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSKAQSGRADEINT
                     CIGCNQACLDQIFVGKVTSCLVNPRACHETKMPILPAVQKKNLAVVGAGPAGLAFAIN
                     AAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYRRMIEVTGVTLKLNHTVT
                     ADQLQSFDETILASGIVPRIPPIDGIDHPKVLSYLDVLRDKAPVGKKVAIIGCGGIGF
                     DTAMFLSQPGESTSKNIAEFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVMLQRKAS
                     KPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDDDGLHVVINGETQVLAVDNVVIC
                     AGQEPNRALAQPLIDSGKTVHLIGGCDVAMELDARRAIAQGTRLALEI"
     gene            complement(35364..37715)
                     /gene="ygjK"
                     /locus_tag="IT892_000131"
     CDS             complement(35364..37715)
                     /gene="ygjK"
                     /locus_tag="IT892_000131"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP3133387.1"
                     /translation="MKIKTILTPVTCALLISFSAHAADADNYKNVINRTGAPQYMKDY
                     DYDDHQRFNPFFDLGAWHGHLLPDGPNTMGGFPGVALLTEEYINFMASNFDRLTVWQD
                     GKKVDFTLEAYSIPGALVQKLTAKDVQVEMTLRFATPRTSLLETKITSNKPLDLVWDG
                     ELLEKLEAKEGKPLSDKTIAGEYPDYQRKISATRDGLKVTFGKVRATWDLLTSGESEY
                     QVHKSLPVQTEINGNRFTSKAHINGSTTLYTTYSHLLTAQEVSKEQMQIRDILARPAF
                     YLTASQQRWEEYLKKGLTNPDATPEQTRVAVKAIETLNGNWRSPGGAVKYNTVTPSVT
                     GRWFSGNQTWPWDTWKQAFAMAHFNPDIAKENIRAVFSWQIQPGDRVRPQDVGFVPDL
                     IAWNLSPERGGDGGNWNERNTKPSLAAWSVMEVYNVTQDKAWLAEMYPKLVAYHDWWL
                     RNRDHNGNGVPEYGATRDKAHNTESGEMLFTVKKGDKEETQSGLNNYARVVEKGQYDS
                     LEIPAQVAASWESGRDDAAVFGFIDKEQLDKYVANGGKRSDWTVKFAENRSQDGTLLG
                     YSLLQESVDQASYMYSDNHYLAEMATILGKPEEAQRYRQLAQQLADYINTCMFDPTTQ
                     FYYDVRIEDKPLANGCAGKPIVERGKGPEGWSPLFNGAATQANADAVVKVMLDPKEFN
                     TFVPLGTAALTNPAFGADIYWRGRVWVDQFWFGLKGMERYGYRDDALKLADTFFQHAK
                     GLTADGPIQENYNPLTGAQQGAPNFSWSAAHLYMLYNDFFRKQ"
     gene            complement(37732..38802)
                     /gene="ygjJ"
                     /locus_tag="IT892_000132"
     CDS             complement(37732..38802)
                     /gene="ygjJ"
                     /locus_tag="IT892_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgjJ"
                     /protein_id="HAP3133388.1"
                     /translation="MKLITAPCRALLALPFCYAFSAAGEEVRPAEHDDTKTPAITSMS
                     SPSFRFYGELGVGGYMDLEGENKHKYSDGTYIEGGLEMKYGSWFGLIYGEGWTVQADH
                     DGNAWVPDHSWGGFEGGINRFYGGYRTNDGTEIMLSLRQDSSLDDLQWWGDFTPDLGY
                     VIPNTRDIMTALKVQNLSGNFRYSVTATPAGHHDESKAWLHFGKYDRYDDKYTYPAMM
                     NGYIQYDLAEGITWMNGLEITDGTGQLYLTGLLTPNFAARAWHHTGRADGLDVPGSES
                     GMMVSAMYEALKGVYLSTAYTYAKHRPDHADDETTSFMQFGIWYEYGGGRFATAFDSR
                     FYMKNASHDPSDQIFLMQYFYW"
     gene            complement(38936..40369)
                     /locus_tag="IT892_000133"
     CDS             complement(38936..40369)
                     /locus_tag="IT892_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP3133389.1"
                     /translation="MSDTKRNTIGKFGLLSLTFAAVYSFNNVINNNIELGLASAPMFF
                     LATIFYFIPFCLIIAEFVSLNKNSEAGVYAWVKSSLGGRWAFITAYTYWFVNLFFFTS
                     LLPRVIAYASYAFLGYEYIMTPVATTIISMVLFAFSTWVSTNGAKMLGPITSVTSTLM
                     LLLTLSYILLAGTALVGGVQPADPITVDAMIPNFNWAFLGVTTWIFMAAGGAESVAVY
                     VNDVKGGSKSFVKVIILAGIFIGVLYSVSSVLINVFVSSKELKFTGGSVQVFHGMAAY
                     FGLPEALMNRFVGLVSFTAMFGSLLMWTATPVKIFFSEIPEGIFGKKTVELNENGVPA
                     RAAWIQFLIVIPLMIIPMLGSNTVQDLMNTIINMTAAASMLPPLFIMLAYLNLRAKLD
                     HLPRDFRMGSRRTGIIVVSMLIAIFAVGFVASTFPTGANILTIIFYNVGGIVIFLGFA
                     WWKYSKYIKGLTAEERHIEATPASNVD"
     gene            complement(40432..40881)
                     /locus_tag="IT892_000134"
     CDS             complement(40432..40881)
                     /locus_tag="IT892_000134"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit beta"
                     /protein_id="HAP3133390.1"
                     /translation="MRIIDNLEQFRQIYASGKKWQRCVEAIENIDNIQPSVAHSIGDS
                     LTYRVENDSATDALFTGHRRYFEVHYYLQGQQKIEYAPKETLQVVEYYRDETDREYLK
                     GCGETVEVHEGQIVICDIHEAYRFICNNAVKKVVLKVTIEDGYFHNK"
     gene            complement(40878..43970)
                     /gene="ebgA"
                     /locus_tag="IT892_000135"
     CDS             complement(40878..43970)
                     /gene="ebgA"
                     /locus_tag="IT892_000135"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311985.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit alpha"
                     /protein_id="HAP3133391.1"
                     /translation="MNRWENIQLTHANRLAPRAYFFSYDSVAQARTFARETSSLFLPL
                     SGQWNFHFFDHPLQVPEAFTSELMADWGHITVPAMWQMEGHGKLQYTDEGFPFPIDVP
                     FVPSDNPTGAYQRIFTLSDGWQGKQTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF
                     DISAMVKTGDNLLCVRVMQWADSTYVEDQDMWWSAGIFRDVYLVGKQLTHINDFTVRT
                     DFDEAYCDATLSCEVVLENLAASPVVTTLEYTLFDGERVVHSSAIDHLAIEKLTSASF
                     AFTVEQPQQWSAESPYLYHLVMTLKDADGNVLEVVPQRVGFRDIKVRDGLFWINNRYV
                     MLHGVNRHDNDHRKGRAVGMDRVEKDLQLMKQHNINSVRTAHYPNDPRFYELCDIYGL
                     FVMAETDVESHGFANVGDISRITDDPQWEKVYVERIVRHIHAQKNHPSIIIWSLGNES
                     GYGCNIRAMYHAAKALDDTRLVHYEEDRDAEVVDIISTMYTRVPLMNEFGEYPHPKPR
                     IICEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVWEWCDHGIQAQDDNGNVWYKFGGD
                     YGDYPNNYNFCLDGLIYSDQTPGPGLKEYKQVIAPVKIHALDLTRGELKVENKLWFTT
                     LDDYTLHAEVRAEGETLATQQIKLRDVAPNSEAPLQITLPQLDAREAFLNITVTKDSR
                     TRYSEAGHSIATYQFPLKENTAQPVPFAPNNARPLTLEDDRLSCTVRGYNFAITFSKM
                     SGKPTSWQVNGESLLTREPKINFFKPMIDNHKQEYEGLWQPNHLQIMQEHLRDFAVEQ
                     SDGEVLIISRTVIAPPVFDFGMRCTYIWRIAADGQVNVALSGERYGDYPHIIPCIGFT
                     MGINGEYDQVAYYGRGPGENYADSQQANIIDIWRSTVDAMFENYPFPQNNGNRQHVRW
                     TALTNRHGNGLLVVPQRPINFSAWHYTQENIHAAQHCNELQRSDDITLNLDHQLLGLG
                     SNSWGSEVLDSWRVWFRDFSYGFTLLPVSGGEATAQSLASYEFGAGFFSTNLHSENKQ
                     "
     gene            complement(44154..45137)
                     /gene="ebgR"
                     /locus_tag="IT892_000136"
     CDS             complement(44154..45137)
                     /gene="ebgR"
                     /locus_tag="IT892_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator EbgR"
                     /protein_id="HAP3133392.1"
                     /translation="MATLKDIAIEAGVSLATVSRVLNDDPTLNVKEETKHRILEIAEK
                     LEYKTSSARKLQTGAVNQHHILAIYSYQQELEINDPYYLAIRHGIETQCEKLAIELTN
                     CYEHSGLPDIKNVTGILIVGKPTPALRAAACALTDNICFIDFHEPGSGYDAVDIDLAR
                     ISKEIIDFYINQGVNRIGFIGGEDEPGKADIREVAFAEYGRLKQVVREEDIWRGGFSS
                     SSGYELAKQMLAREDYPKALFVASDSIAIGVLRAIHERGLNIPQDISLISVNDIPTAR
                     FTFPPLSTVRIHSEMMGSQGVNLVYEKARDGRALPLLVFVPSKLKLRGTTR"
     gene            45356..45688
                     /locus_tag="IT892_000137"
     CDS             45356..45688
                     /locus_tag="IT892_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HAP3133393.1"
                     /translation="METVAYADFARLEMRVGKIVEVKRHENADKLYIVQVDVGEKTLQ
                     TVTSLVPYYSEEELMGKTVVVLCNLQKAKMRGETSECMLLCAETDDGSESVLLTPERM
                     MPAGVRIV"
     gene            complement(45730..47220)
                     /gene="ygjG"
                     /locus_tag="IT892_000138"
     CDS             complement(45730..47220)
                     /gene="ygjG"
                     /locus_tag="IT892_000138"
                     /EC_number="2.6.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311982.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine aminotransferase"
                     /protein_id="HAP3133394.1"
                     /translation="MITTFVFIPIFAIAAGVAQSLQYLNRYHVIREPPEHILNRLPSS
                     ASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGA
                     VEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLD
                     PLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFH
                     GKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALSECKKTGDDVAAVILEP
                     IQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILC
                     LAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNL
                     PAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEIGYNFASEMFRQRV
                     LVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA"
     gene            47527..49047
                     /locus_tag="IT892_000139"
     CDS             47527..49047
                     /locus_tag="IT892_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HAP3133395.1"
                     /translation="MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYT
                     LQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPM
                     VREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLP
                     LRWRARGVMTLMFILLAVMLWFVAAPVVTYILCALVVLLASACFEWQIVRPIENVARQ
                     ALKVATGERNSVEHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAK
                     GTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAM
                     TTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGE
                     VRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQIS
                     HSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQVSAMVKHRASRLEDAVTVLH"
     gene            complement(49154..49777)
                     /locus_tag="IT892_000140"
     CDS             complement(49154..49777)
                     /locus_tag="IT892_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP3133396.1"
                     /translation="MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCG
                     GRHGRGGGRRQRFFGHGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYP
                     TLDFLQEQSLITIREEEGGKKQIALTEQGAQWLEENREQVEMIEERIKARCVGAALRQ
                     NPQMKRALDNFKAVLDLRVNQSDITDAQIKKIIAVIDRAAFDITQLD"
     gene            50054..50818
                     /gene="nfeF"
                     /locus_tag="IT892_000141"
     CDS             50054..50818
                     /gene="nfeF"
                     /locus_tag="IT892_000141"
                     /EC_number="1.16.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent ferric chelate reductase"
                     /protein_id="HAP3133397.1"
                     /translation="MNNSPRYPQRVRNDLRFRELTVLRAERISAGFQRIVLGGEALDG
                     FTSRGFDDHSKLFFPQSDAHFVPPTVTEEGIVWPEGPRPPSRDYTPLYDELRHELAID
                     FFIHDGGVASSWAMQAQPGDKLTVAGPRGSLVVPEDYAYQLYVCDESGMPALRRRLET
                     LSKLAVKPQVSALVSVRDHACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYF
                     IWITGEGKVVKNLSRRFEAEQYDPQRVRAAAYWHAK"
     gene            complement(50872..50947)
                     /locus_tag="IT892_000142"
     tRNA            complement(50872..50947)
                     /locus_tag="IT892_000142"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(50912..50914),aa:Ile,seq:cat)
     gene            51072..51578
                     /gene="mug"
                     /locus_tag="IT892_000143"
     CDS             51072..51578
                     /gene="mug"
                     /locus_tag="IT892_000143"
                     /EC_number="3.2.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="HAP3133398.1"
                     /translation="MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQA
                     GFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQ
                     ALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELD
                     QALVVRGR"
     gene            complement(51657..53498)
                     /gene="rpoD"
                     /locus_tag="IT892_000144"
     CDS             complement(51657..53498)
                     /gene="rpoD"
                     /locus_tag="IT892_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAP3133399.1"
                     /translation="MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDI
                     IQMINDMGIQVMEEAPDADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYM
                     REMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSD
                     LITGFVDPNAEEDLAPTATHVGSELSQEDLDDDEDEDEEDGDDDSADDDNSIDPELAR
                     EKFAELRAQYVVTRDTIKAKGRSHAAAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM
                     MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVS
                     EEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAK
                     KYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
                     RIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISME
                     TPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGID
                     MNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD"
     gene            complement(53693..55438)
                     /gene="dnaG"
                     /locus_tag="IT892_000145"
     CDS             complement(53693..55438)
                     /gene="dnaG"
                     /locus_tag="IT892_000145"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAP3133400.1"
                     /translation="MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHN
                     EKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAG
                     SGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVATSARQYLEKRGLSHEVIARFAIGF
                     APPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGF
                     GGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQY
                     GINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQ
                     LRFMFLPDGEDPDTLVRKEGKQAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLS
                     TLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTT
                     MRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYR
                     GTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNE
                     ERLELWTLNQELAKK"
     gene            complement(55549..55764)
                     /gene="rpsU"
                     /locus_tag="IT892_000146"
     CDS             complement(55549..55764)
                     /gene="rpsU"
                     /locus_tag="IT892_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAP3133401.1"
                     /translation="MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTE
                     RKRAKASAVKRHAKKLARENARRTRLY"
     gene            56002..57015
                     /gene="tsaD"
                     /locus_tag="IT892_000147"
     CDS             56002..57015
                     /gene="tsaD"
                     /locus_tag="IT892_000147"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAP3133402.1"
                     /translation="MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVP
                     ELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAW
                     DVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
                     AAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFA
                     ANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLR
                     AKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAEL
                     PAA"
     gene            complement(57058..58521)
                     /locus_tag="IT892_000148"
     CDS             complement(57058..58521)
                     /locus_tag="IT892_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HAP3133403.1"
                     /translation="MKPSTEWWRYLAPLAVIAIIALIPVPAGLESHTWLYFAVFTGVI
                     VGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSV
                     IWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSA
                     RGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLL
                     IGLMKSASHATLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETEL
                     QAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSN
                     KAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLNGYSPTMVMVALIVVFYLLRY
                     FFASATAYTSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYG
                     SGYLPTVDYWRLGAIFGLIFLVLLVITGLLWMPMVLL"
     gene            complement(58570..59175)
                     /gene="ttdB"
                     /locus_tag="IT892_000149"
     CDS             complement(58570..59175)
                     /gene="ttdB"
                     /locus_tag="IT892_000149"
                     /EC_number="4.2.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit beta"
                     /protein_id="HAP3133404.1"
                     /translation="MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELK
                     RPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGK
                     GGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEF
                     GPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK"
     gene            complement(59172..60083)
                     /gene="ttdA"
                     /locus_tag="IT892_000150"
     CDS             complement(59172..60083)
                     /gene="ttdA"
                     /locus_tag="IT892_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit alpha"
                     /protein_id="HAP3133405.1"
                     /translation="MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAE
                     TSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVE
                     EATVKAPLRHNAVEIFDEVNTDKNTGSGVPWVTWDIVPDGDDAEIEVYMAGGGCTLPG
                     RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPI
                     GSRHPNPKAAELELRLEEGLNRLGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTG
                     CWAHRRGTLLVHADLTFENLSHTRSAL"
     gene            60290..61222
                     /gene="ttdR"
                     /locus_tag="IT892_000151"
                     /gene_synonym="dan"
     CDS             60290..61222
                     /gene="ttdR"
                     /locus_tag="IT892_000151"
                     /gene_synonym="dan"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TtdR"
                     /protein_id="HAP3133406.1"
                     /translation="MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQIL
                     ENTLATTLLNRSARGVALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGC
                     SFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAH
                     LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVK
                     VSGHLSSNSGEIVLQWALEGKGIMLRSEWDVLPFLESGKLVRVLPEYAQSANIWAVYR
                     EPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQIM"
     gene            complement(61235..61852)
                     /gene="plsY"
                     /locus_tag="IT892_000152"
     CDS             complement(61235..61852)
                     /gene="plsY"
                     /locus_tag="IT892_000152"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAP3133407.1"
                     /translation="MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGAT
                     NVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGF
                     KGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
                     QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE"
     gene            61957..62325
                     /gene="folB"
                     /locus_tag="IT892_000153"
     CDS             61957..62325
                     /gene="folB"
                     /locus_tag="IT892_000153"
                     /EC_number="4.1.2.25"
                     /EC_number="5.1.99.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional dihydroneopterin
                     aldolase/7,8-dihydroneopterin epimerase"
                     /protein_id="HAP3133408.1"
                     /translation="MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKS
                     DDVADCLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKPGAV
                     ARAANVGVIIERGNNLKENN"
     gene            62416..63237
                     /gene="bacA"
                     /locus_tag="IT892_000154"
     CDS             62416..63237
                     /gene="bacA"
                     /locus_tag="IT892_000154"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAP3133409.1"
                     /translation="MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT
                     AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPA
                     VVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
                     GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGF
                     LTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF"
     gene            complement(63318..64556)
                     /gene="cca"
                     /locus_tag="IT892_000155"
     CDS             complement(63318..64556)
                     /gene="cca"
                     /locus_tag="IT892_000155"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused tRNA nucleotidyltransferase/2',3'-cyclic
                     phosphodiesterase/2' nucleotidase/phosphatase Cca"
                     /protein_id="HAP3133410.1"
                     /translation="MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGR
                     DFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDD
                     NGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLALM
                     REMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPA
                     PARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPA
                     GVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQR
                     VEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREEL
                     TRRRIAAVASWKEQRCPKPD"
     gene            complement(64620..65240)
                     /locus_tag="IT892_000156"
     CDS             complement(64620..65240)
                     /locus_tag="IT892_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HAP3133411.1"
                     /translation="MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDHY
                     RLVGTVNAGEEVTLLQTDANTNYAQVKDSSGRTAWIPLKQLSTEPSLRSRVPDLENQV
                     KTLTDKLTNIDNTWNQRTAEMQQKVAQSDSVINGLKEENQKLKNELIVAQKKVDAASV
                     QLDDKQRTIIMQWFMYGGGVLGLGLLLGLVLPHLIPSRKRKDRWMN"
     gene            65482..66783
                     /locus_tag="IT892_000157"
     CDS             65482..66783
                     /locus_tag="IT892_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic triphosphatase"
                     /protein_id="HAP3133412.1"
                     /translation="MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETP
                     DNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEV
                     WPNGELPTDLASRVQPLFSTDFYREKWLVEVDGSQIEIALDQGEVKAGEFAEPICELE
                     LELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAK
                     ADVEQGLEAALELALAQWQYHEELWVRGNDAAKEQVLAAISLVRHTLMLFGGIVPRKA
                     STHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQSKI
                     SDSFKRFADIHLSRHAAELKSVFCQPLGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQ
                     AWLENWQGLRHAIATGQRIEIEHFRNEANNQEPFWLHSGKR"
     gene            66806..69646
                     /gene="glnE"
                     /locus_tag="IT892_000158"
     CDS             66806..69646
                     /gene="glnE"
                     /locus_tag="IT892_000158"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HAP3133413.1"
                     /translation="MKPLSSPLQQYWQTVVERLPEPLAEESLSAQAKSVLTFSDFVQD
                     SVIAHPEWLTELESQPPQADEWQHYAAWLQEALCNVSDEAGLMRELRLFRRRIMVRIA
                     WAQTLALVTEESILQQLSYLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGM
                     GKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGF
                     VYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELR
                     AMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQ
                     LIRGGREPSLQSRSLLPTLSAIAELHLLSENDAEQLRVAYLFLRRLENLLQSINDEQT
                     QTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSE
                     QWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLM
                     PHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIA
                     SQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQ
                     LLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRG
                     FAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFS
                     TRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQ
                     LTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIE
                     FITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHL
                     ALQELPGHVSEDCFTAERELVRASWQKWLVEE"
     gene            69694..71127
                     /gene="hldE"
                     /locus_tag="IT892_000159"
     CDS             69694..71127
                     /gene="hldE"
                     /locus_tag="IT892_000159"
                     /EC_number="2.7.1.167"
                     /EC_number="2.7.7.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     D-glycero-beta-D-manno-heptose-7-phosphate
                     kinase/D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase HldE"
                     /protein_id="HAP3133414.1"
                     /translation="MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVN
                     TIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHP
                     TITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASV
                     QQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMK
                     LIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAA
                     GNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAA
                     ARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNP
                     LEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANG
                     GEVLVLNFEDGCSTTNIIKKIQQDKKG"
     gene            complement(71247..71306)
                     /gene="ibsE"
                     /locus_tag="IT892_000160"
     CDS             complement(71247..71306)
                     /gene="ibsE"
                     /locus_tag="IT892_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsE"
                     /protein_id="HAP3133415.1"
                     /translation="MMKLVIILVVLLLLSFPTY"
     gene            complement(71622..71681)
                     /locus_tag="IT892_000161"
     CDS             complement(71622..71681)
                     /locus_tag="IT892_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HAP3133416.1"
                     /translation="MMKLVIILIVLLLVSFAAY"
     gene            complement(71922..73583)
                     /locus_tag="IT892_000162"
     CDS             complement(71922..73583)
                     /locus_tag="IT892_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAP3133417.1"
                     /translation="MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVR
                     TGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRSTIDSLITKDRMRVDVVVAFF
                     VRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
                     VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRR
                     ERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQEQQVKTRTAEQNARIAAFEA
                     ERRREAEQTRILAERQIQETEIDREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKS
                     IAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETK
                     AVELTVRAKAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLK
                     FKLALLQALPAVIEKSVEPMKSIDGIKIIQVDGLNRGGAAGDANTGNVGGGNLAEQAL
                     SAALSYRTQAPLIDSLLNEIGVSGGSLAALTSPLTSTTPVEEKAE"
     gene            complement(73610..74239)
                     /locus_tag="IT892_000163"
     CDS             complement(73610..74239)
                     /locus_tag="IT892_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqiJ family protein"
                     /protein_id="HAP3133418.1"
                     /translation="MILFADYNTPYLFAISFVLLIGLLEIFALICGHMLSGALDAHLD
                     HYDSITTGHISQALHYLNIGRLPALVVLCLLAGFFGLIGILLQHACIMVWQSPLSNLF
                     VVPVSLLFTIIAVHYTGKIVAPWIPRDHSSAITEEEYIGSMALITGHQATSGNPCEGK
                     LTDQFGQIHYLLLEPEEGKIFTKGDKVLIICRLSATRYLAENNPWPQIL"
     gene            74508..74708
                     /gene="glgS"
                     /locus_tag="IT892_000164"
     CDS             74508..74708
                     /gene="glgS"
                     /locus_tag="IT892_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface composition regulator GlgS"
                     /protein_id="HAP3133419.1"
                     /translation="MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTW
                     FCARYAWYCQQMMQARELELEH"
     gene            complement(74751..75815)
                     /locus_tag="IT892_000165"
     CDS             complement(74751..75815)
                     /locus_tag="IT892_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3133420.1"
                     /translation="MRYLLIVITFFMGFSSLPAWAMDCYAEHEGGNTVVIGYVPRISI
                     PSDGKKGDKIWQSSEYFMNVFCNNALPGPSPGEESPSAWANIMMLLASGQDFYNQNSY
                     TFGVTYNGVDYDSTSPLPIAAPVCIDIKGAGTFGNGYKKPAVCSGGPEPQLSVTFPVR
                     VQLYIKLAKNANKVNKKLVLPDEYITLEFKGMSGAGAIEVDKNLTFRIRGLNNIHVLD
                     CFVNVDLEPADGVVDFGKINSRTIKNTSVSETFSVVMTKDPGAACTEQFNILGSFFTT
                     DILSDYSHLDIGNGLLLKIFHNDGTATEFNRFSQFASFSSSSAPSVTAPFRAELSANP
                     AETVVEGPFSKDVILKITYN"
     gene            complement(75817..76566)
                     /locus_tag="IT892_000166"
     CDS             complement(75817..76566)
                     /locus_tag="IT892_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417519.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HAP3133421.1"
                     /translation="MRYLNTKNIIAAGVLLSCMSSIAWGAIIPDRTRIIMNESDKGEA
                     LKLTNQSKNLPYLAQTWIEDTKGNKSRDFIVTVPPMVRLNPSEQIQIRMITQEKIAQL
                     PKDRETLFYFNVREIPPKTDKKNVMQVTMQHALKLFWRPKAIELEDDGVMTYEKVEII
                     RRNDGSIRFNNKMPYHVTLGYIGTNGVTMLPQTQSLMVTPFSYANTQFKNVPSTFQVG
                     YINDFGGLSFYEINCPVVNNICNISVANRDQ"
     gene            complement(76582..79086)
                     /locus_tag="IT892_000167"
     CDS             complement(76582..79086)
                     /locus_tag="IT892_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HAP3133422.1"
                     /translation="MYKKLKLTTISELIKNIYCSLSVIIIGCASAYAVEFNKDLIEAE
                     DRENVNLSQFETDGQLPVGKYSLSTLINNKRTPIHLDLQWVLIDNQTAVCVTPEQLTL
                     LGFTDEFIEKTQQNLIDGCYPIEKEKQITTYLDKGKMQLSISAPQAWLKYKDANWTPP
                     ELWNHGIAGAFLDYNLYASHYAPHQGDNSQNISSYGQAGVNLGAWRLRTDYQYDQSFN
                     NGKSQATNLDFPRIYLFRPIPAMNAKLTIGQYDTESSIFDSFHFSGISLKSDENMLPP
                     DLRGYAPQITGVAQTNAKVTVSQNNRIIYQENVPPGPFAITNLFNTLQGQLDVKVEEE
                     DGRVTQWQVASNSIPYLTRKGQIRYTTAMGKPTSVGGDSLQQPFFWTGEFSWGWLNNV
                     SLYGGSVLTNRDYQSLAAGVGFNLNSLGSLSFDVTRSDAQLHNQDKETGYSYRANYSK
                     RFESTGSQLTFAGYRFSDKNFVTMNEYINDTNHYTNYQNEKESYIVTFNQYLESLRLN
                     TYVSLARNTYWDASSNVNYSLSLSRDFDIGPLKNVSTSLTFSRINWEEDNQDQLYLNI
                     SIPWGTSRTLSYGMQRNQDNEISHTASWYDSSDRNNSWSVSASGDNDEFKDMKASLRA
                     SYQHNTENGRLYLSGTSQRDSYYSLNASWNGSFTATRHGAAFHDYSGSADSRFMIDAD
                     GTEDIPLNNKRAVTNRYGIGVIPSVSSYITTSLSVDTRNLPENVDIENSVITTTLTEG
                     AIGYAKLDTRKGYQIIGVIRLADGSHPPLGISVKDETSHKELGLVADGGFVYLNGIQD
                     DNKLALRWGDKSCFIQPPNSSNLTTGTAILPCISQN"
     gene            complement(79146..79697)
                     /locus_tag="IT892_000168"
     CDS             complement(79146..79697)
                     /locus_tag="IT892_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein"
                     /protein_id="HAP3133423.1"
                     /translation="MSAFKKSLLVAGVAMILSNNVFADEGHGIVKFKGEVISAPCSIK
                     PGDEDLTVNLGEVADTVLKSDQKSLAEPFTIHLQDCMLSQGGTTYSKAKVTFTTANTM
                     TGQSDLLKNTKETEIGGATGVGVRILDSQSGEVTLGTPVVITFNNTNSYQELNFKARM
                     ESPSKDATPGNVYAQADYKIAYE"
     gene            complement(79981..80271)
                     /locus_tag="IT892_000169"
     CDS             complement(79981..80271)
                     /locus_tag="IT892_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory factor UbiK family protein"
                     /protein_id="HAP3133424.1"
                     /translation="MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRQTLQAQLTRL
                     DLVSREEFDVQTQVLLRTREKLALLEQRISELENRSTEIKKQPDPETLPPTL"
     regulatory      80393..80541
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            80645..81298
                     /gene="ribB"
                     /locus_tag="IT892_000170"
     CDS             80645..81298
                     /gene="ribB"
                     /locus_tag="IT892_000170"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HAP3133425.1"
                     /translation="MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMI
                     FPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAA
                     EGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
                     MTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS"
     gene            81560..81730
                     /locus_tag="IT892_000171"
     CDS             81560..81730
                     /locus_tag="IT892_000171"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133426.1"
                     /translation="MFIAWYWIVLIALVVVGYFLHLKRYCRAFRQDRDALLEARNKYL
                     NSTREETAEKVE"
     gene            complement(81788..82561)
                     /gene="zupT"
                     /locus_tag="IT892_000172"
     CDS             complement(81788..82561)
                     /gene="zupT"
                     /locus_tag="IT892_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HAP3133427.1"
                     /translation="MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIM
                     LLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLP
                     KSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
                     YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVD
                     ELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG"
     gene            82677..83492
                     /gene="ygiD"
                     /locus_tag="IT892_000173"
     CDS             82677..83492
                     /gene="ygiD"
                     /locus_tag="IT892_000173"
                     /EC_number="1.13.11.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417511.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,5-DOPA dioxygenase extradiol"
                     /protein_id="HAP3133428.1"
                     /translation="MTPLVKDIIMSSTRMPALFLGHGSPMNVLEDNLYTRSWQKLGMT
                     LPRPQAIVVVSAHWFTRGTGVTAMETPPTIHDFGGFPQALYDTHYPAPGSPALAQRLV
                     ELLAPIPVTLDKEAWGFDHGSWGVLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLA
                     ALRDEGIMLVASGNVVHNLRTVKWHGDSSPYPWATSFNEYVKANLTWQGPVEQHPLVN
                     YLDHEGGTLSNPTPEHYLPLLYVLGAWDGQEPITIPVEGIEMGSLSMLSVQIG"
     gene            complement(83530..84690)
                     /locus_tag="IT892_000174"
     CDS             complement(83530..84690)
                     /locus_tag="IT892_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HAP3133429.1"
                     /translation="MERVSITERPDWREKAHEYGFNFHTMYGEPYWCEDAYYKLTLAQ
                     VEKLEEVTAELHQMCLKVVEKVIASDELMTKFRIPKHTWSFVRQSWLTHQPSLYSRLD
                     LAWDGTGEPKLLENNADTPTSLYEAAFFQWIWLEDQLNAGNLPEGSDQFNSLQEKLID
                     RFVELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCATEAEIATEFLYIDDIGLGEKGQ
                     FTDLQDQVISNLFKLYPWEFMLREMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEM
                     FPNHPNLLPAYFAEDDHPQMEKYVVKPIFSREGANVSIIENGKTIEAAEGPYGEEGMI
                     VQQFHPLPKFGDSYMLIGSWLVNDQPAGIGIREDRALITQDMSRFYPHIFVE"
     gene            complement(84696..85367)
                     /locus_tag="IT892_000175"
     CDS             complement(84696..85367)
                     /locus_tag="IT892_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417509.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 family protein"
                     /protein_id="HAP3133430.1"
                     /translation="MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETV
                     SLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPA
                     QAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
                     TDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSS
                     RSMGG"
     gene            complement(85515..86996)
                     /gene="tolC"
                     /locus_tag="IT892_000176"
     CDS             complement(85515..86996)
                     /gene="tolC"
                     /locus_tag="IT892_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane channel protein TolC"
                     /protein_id="HAP3133431.1"
                     /translation="MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAA
                     DRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSK
                     WRALTLQEKAAGIQDVTHQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLD
                     QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAAL
                     NVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTAST
                     GISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGA
                     SEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIV
                     DVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
                     NVAPQTPEQNAIADGYAPDSPAPVVQQTSARTTTSNGHNPFRN"
     gene            87201..87830
                     /gene="nudF"
                     /locus_tag="IT892_000177"
     CDS             87201..87830
                     /gene="nudF"
                     /locus_tag="IT892_000177"
                     /EC_number="3.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase"
                     /protein_id="HAP3133432.1"
                     /translation="MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQ
                     MSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEG
                     ESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLA
                     DENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA"
     gene            87831..88253
                     /locus_tag="IT892_000178"
     CDS             87831..88253
                     /locus_tag="IT892_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1249 family protein"
                     /protein_id="HAP3133433.1"
                     /translation="MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQ
                     YRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARY
                     DYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY"
     gene            88278..89105
                     /gene="cpdA"
                     /locus_tag="IT892_000179"
     CDS             88278..89105
                     /gene="cpdA"
                     /locus_tag="IT892_000179"
                     /EC_number="3.1.4.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-AMP phosphodiesterase"
                     /protein_id="HAP3133434.1"
                     /translation="MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQA
                     VLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY
                     SALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
                     LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLL
                     ATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY"
     gene            89105..89686
                     /gene="yqiA"
                     /locus_tag="IT892_000180"
     CDS             89105..89686
                     /gene="yqiA"
                     /locus_tag="IT892_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase YqiA"
                     /protein_id="HAP3133435.1"
                     /translation="MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYP
                     SDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDY
                     LGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
                     SCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL"
     gene            89715..91607
                     /gene="parE"
                     /locus_tag="IT892_000181"
     CDS             89715..91607
                     /gene="parE"
                     /locus_tag="IT892_000181"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAP3133436.1"
                     /translation="MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSV
                     DEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSN
                     KNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN
                     TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDG
                     LNDYLAEAVNGLPTLPEKPFIGNFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQG
                     GTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTK
                     ERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLT
                     SGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEV
                     SSDEVLAAQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVK
                     HFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNVQRFKGL
                     GEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGD
                     MAEIEV"
     gene            complement(91655..91969)
                     /locus_tag="IT892_000182"
     CDS             complement(91655..91969)
                     /locus_tag="IT892_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAP3133437.1"
                     /translation="MLTVIAEIRTRPGQHHRQAVLDQFAKIVPTVLKEEGCHGYAPMV
                     DCAAGVSFQSMAPDSIVMIEQWESIAHLEAHLQTPHMKAYSEAVKGDVLEMNIRILQP
                     GI"
     gene            complement(92000..92581)
                     /gene="mdaB"
                     /locus_tag="IT892_000183"
     CDS             complement(92000..92581)
                     /gene="mdaB"
                     /locus_tag="IT892_000183"
                     /EC_number="1.6.5.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone oxidoreductase MdaB"
                     /protein_id="HAP3133438.1"
                     /translation="MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRA
                     DSDYDVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRK
                     DPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
                     EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG"
     gene            92900..93232
                     /locus_tag="IT892_000184"
     CDS             92900..93232
                     /locus_tag="IT892_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeO family protein"
                     /protein_id="HAP3133439.1"
                     /translation="MLKQKIKTIFEALLYIMLTYWLIDSFFAFNKYDWMLESGGNICS
                     IPSVSGEDRILQAMIAAFFLLTPLIVLILRKLFMREMFEFWVYVFSLGICLVCGWWLF
                     WGRFIFCY"
     gene            complement(93278..>94315)
                     /gene="qseC"
                     /locus_tag="IT892_000185"
     CDS             complement(93278..>94315)
                     /gene="qseC"
                     /locus_tag="IT892_000185"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     QseC"
                     /protein_id="HAP3133440.1"
                     /translation="GEDIPYSYQREGFADGQLVGEDDPWRFVWMTSPDGKYRIVVGQE
                     WEYREDMALAIVAGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKP
                     LNATGVPSEVRPLVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQL
                     SDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVM
                     DIYHTAQQAKIDVRLTLNAHSIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTLNA
                     DNFIVRDNGPGVTPEALARIGERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVEFGNA
                     EQGGFEAKVSW"
BASE COUNT        22738 a        23399 c        24666 g        23512 t
ORIGIN      
        1 ttgttcgaga tgatcaatac ctgtattcga aattttaaaa tattgataaa ataaatgttt
       61 gttctccaac aaatagcgtg aaaaaatgtg acgtgccgca ttatttatcg ctgaaaatga
      121 tttatttata ataaaatttg agaacttgct cattaaattt aactcaaaat ttgcctggta
      181 attatccggt aattgcttga aatatggtct cagccccttt tttgtattaa ccacataacg
      241 aataatgtta tcgccataaa atatggttat ccccgtcatt ttttttgaca aaaatcaggg
      301 tttatgctga tttttatact ttaacttatt tgatatataa agatatttaa ttggaataac
      361 gataccctga aaagtattga aagttaattt gtgagtggtc gcacatatcc tgttcatttc
      421 attttgatac acttcatgcc gtcaatgagg taattaacgt aggtcgttat gagcactatt
      481 cttcttccga aaacgcagca cctggtagtc tttcaggaag tcattagaag tggctctatc
      541 ggctcggctg caaaagaatt agggttaact caaccggccg tcagtaaaat cattaacgat
      601 attgaagatt attttggcgt ggaattagtg gtgcggaaaa ataccggtgt aacattaaca
      661 cctgccggtc aattgttact ctcccgttcc gaatccatta cccgtgaaat gaaaaatatg
      721 gttaatgaga taagcggtat gtcttctgag gcggtggtgg aagtctcatt tggttttcct
      781 tcattgattg gttttacttt tatgtcaggg atgatcaaca agttcaaaga ggtgttcccg
      841 aaagcgcagg tttctatgta tgaagcgcaa ctgtcttcgt tcttaccggc aatccgcgac
      901 ggtcgactgg attttgcgat tggtacgtta agcgcagaaa tgaagcttca ggatttacat
      961 gttgagccgc tgttcgagtc cgagtttgtg ctggtagcca gtaagtcccg aacatgcacc
     1021 ggtaccacca cgctggagtc gttgaagaac gaacagtggg tgttgccaca aaccaatatg
     1081 gggtactaca gcgagctact tactacgtta caaagaaatg gcatcagtat tgaaaacatc
     1141 gttaaaaccg actcagtcgt gacaatttat aatcttgttc tcaatgctga tttcttaact
     1201 gtaattcctt gtgatatgac atcacctttt ggttcaaatc aatttattac tattccggtt
     1261 gaagaaacat tacctgtggc acaatatgcc gcggtatggt cgaaaaatta tcgtattaaa
     1321 aaagcagcat cggttttggt ggaattagcc aaagagtatt catcttataa tgggtgtaga
     1381 cgaaggcaat taattgaagt tggttagtta tttgttttta tttaaacata aataatccac
     1441 ctgtctgttt tgcaggtgtc ggttacggtt acctacatat ttaattcaga ctaagaggtt
     1501 ttataatgca tattacatac gatctcccgg ttgctattga tgacatcatt gaagcaaaac
     1561 aacgactggc tgggcgaatt tataaaacag gcatgcctcg ctccaactat tttagtgaac
     1621 gttgcaaagg tgaaatattc ctcaaattcg aaaacatgca gcgtaccggt tcatttaaaa
     1681 ttcgtggcgc atttaataaa ttaagttcac tgaccgatgc ggaaaaacgt aaaggtgtag
     1741 tggcctgctc tgcgggcaac catgcgcaag gggtttcgct ctcctgcgcg atgctgggta
     1801 tcgacggtaa agtggtgatg ccaaaaggcg cgccgaaatc caaagtagcg gcaacgtgcg
     1861 actactctgc agaagtcgtt ctgcatggtg ataacttcaa cgacactatc gctaaagtga
     1921 gcgaaattgt cgaaatggaa ggccgtattt ttatcccacc ttatgatgat ccgaaagtga
     1981 ttgctggcca gggaacgatt ggtctggaaa ttatggaaga tctctatgat gtcgataatg
     2041 tgattgtgcc aattggtggt ggcggtttaa ttgctggtat tgcggtggca ataaaatcta
     2101 ttaacccgac cattcgtgtt attggcgtac agtcagaaaa cgttcacggc atggcggctt
     2161 ctttccactc cggagaaata accacgcacc gaactaccgg caccctggcg gatggttgtg
     2221 atgtctcccg cccgggtaat ttaacttacg aaatcgttcg tgaattagtc gatgacatcg
     2281 tgctggtcag cgaagatgaa atcagaaaca gtatgattgc cttaattcag cgcaataaag
     2341 tcgtcaccga aggcgcaggc gctctggcat gtgctgcatt attaagcggt aaattagacc
     2401 aatatattca aaacagaaaa accgtcagta ttatttccgg cggcaatatc gatctttctc
     2461 gcgtctctca aatcaccggt ttcgttgacg cttaattaat tcgttgagga taggatatga
     2521 gtacttcaga tagcattgta tccagccaga caaaacaatc gtcctggcgt aaatcagata
     2581 ccacatggac gttaggcttg tttggtacgg caatcggcgc cggggtgctg ttcttcccta
     2641 tccgcgcagg ttttggcgga ctgatcccga ttcttctgat gttggtatta gcatacccca
     2701 tcgcatttta ttgccaccgg gcgctggcgc gtctgtgtct ttctggctct aacccttccg
     2761 gcaacattac ggaaacggtg gaagagcatt ttggtaaaac aggcggcgtg gttatcacgt
     2821 tcctgtactt cttcgcgatt tgcccactgc tgtggattta tggcgttact attaccaata
     2881 cctttatgac gttctgggaa aaccagctcg gctttgcacc gctgaatcgc ggctttgtgg
     2941 cgctgttcct gttgctgctg atggctttcg tcatctggtt tggtaaggat ctgatggtta
     3001 aagtgatgag ctacctggta tggccgttta tcgccagcct ggtgctgatt tctctgtcgc
     3061 tgatccctta ctggaactct gcagttatcg accaggttga cctcggttcg ctgtcgttaa
     3121 ccggtcatga cggtatcctg atcactgtct ggctggggat ttccatcatg gttttctcct
     3181 ttaacttctc gccaatcgtc tcttccttcg tggtttctaa acgtgaagag tatgagaaag
     3241 acttcgggcg cgacttcacc gaacgtaaat gctcccaaat catttctcgt gccagcatgc
     3301 tgatggttgc agtggtgatg ttctttgcct ttagctgcct gtttacgctg tctccggcca
     3361 acatggcgga agccaaagcg cagaatattc cagtgctttc ttatctggct aaccactttg
     3421 cgtccatgac cggtaccaaa acaacgttcg cgattacact ggaatatgcg gcttccatca
     3481 tcgcactcgt ggctatcttc aaatctttct tcggtcacta tctggggacg ctggaaggct
     3541 tgaatggcct gattctgaag ttcggttata aaggtgacaa aaccaaagtg tcgctgggta
     3601 aactgaatac cctcagcatg atcttcatca tgggctccac ctgggttgtt gcctacgcca
     3661 acccgaacat cctcgacctg attgaagcca tgggcgcacc gattatcgca tcactgctgt
     3721 gcctgttgcc gatgtatgcc attcgtaaag cgccgtctct ggcgaaatac cgtggtcgtc
     3781 tggataacgt gtttgttacc gtgattggtc tgctgaccat cctgaacatc gtatacaaac
     3841 tgttttaatc cgtaactcag gatgagaaaa gagatgaatg aatttccggt tgttttggtt
     3901 attaactgtg gttcgtcttc gattaagttc tccgtgctcg atgctagcga ctgtgaagta
     3961 ttaatgtcag gtattgccga cggtattaac tcggaaaatg cattcttatc cgtaaatggg
     4021 ggagagccag caccgctggc tcaccacagc tacgaaggtg cattgaaggc aattgcattt
     4081 gaactggaaa aacggaattt aaatgacagt gtggccttaa ttggccaccg catcgctcac
     4141 ggcggcagta tttttaccga gtccgccatt attaccgatg aagtcattga taatatccgt
     4201 cgcgtttctc cactggcacc cctgcataat tacgccaatt taagtggtat tgaatcggcg
     4261 cagcaattat ttcctggcgt aactcaggta gcggtatttg ataccagttt ccaccagacg
     4321 atggctccgg aagcttattt atacggcctg ccgtggaaat attatgaaga gttaggtgta
     4381 cgccgttatg gtttccacgg cacgtcgcac cgctatgttt cccagcgcgc gcattctttg
     4441 ctgaatctgg cggaagatga ctccggcctg gttgtggcgc atcttggcaa tggcgcgtca
     4501 atctgcgcag ttcgcaacgg tcagagtgtt gatacctcaa tgggaatgac gccgctggaa
     4561 ggcttgatga tgggtacccg cagtggtgat gtcgacttcg gggcgatgtc ctgggtcgcc
     4621 agccaaacca accagagcct gggtgacctg gaacgcgtag tgaataaaga gtcgggatta
     4681 ttaggtattt ccggtctttc ttcggattta cgtgttctgg aaaaagcctg gcatgaaggt
     4741 cacgaacgcg cgcaactggc aattaaaacc tttgttcacc gaattgcccg tcatattgcc
     4801 ggacacgcag cctcattacg tcgcctggat ggaattatat tcaccggcgg aataggagaa
     4861 aattcaagtt taattcgtcg tctggtcatg gaacatttgg ctgtattagg cgtagagatt
     4921 gatacagaaa tgaataatcg ctctaactcc tgtggagagc gaattgtttc cagtgaaaat
     4981 gcgcgtgtca tttgcgccgt tatcccaacc aacgaagaaa aaatgattgc tttggatgcc
     5041 attcatttag gcaaagtgaa cgcgcccgca gaatttgcat aatttagttg aagtattgta
     5101 gagagattat ttttcatgaa ggtagatatt gataccagcg ataagctgta cgccgacgca
     5161 tggcttggct ttaaaggtac ggactggaaa aacgaaatta atgtccgcga ttttattcaa
     5221 cataactata caccgtatga aggtgatgaa tcttttctcg ccgaagcgac gccagccacc
     5281 acggaattgt gggaaaaggt gatggaaggc attcgtatcg aaaacgcaac ccacgcgccg
     5341 gttgatttcg atactaatat tgctaccacc attaccgctc atgatgcggg atatattaac
     5401 cagccgctgg aaaaaatagt gggcctgcaa acggatgcgc cattaaagcg tgcgctgcat
     5461 ccgttcggtg gcattaatat gattaaaagt tcattccacg cctatggccg tgaaatggac
     5521 agtgaatttg aatatctgtt taccgatctg cgtaaaaccc ataatcaggg cgtatttgat
     5581 gtttactcac cggatatgct gcgctgccgt aaatctggcg tactgaccgg tttgccagat
     5641 ggttatggcc gtgggcgcat tattggtgac taccgccgcg tggcgctgta tggcattcgt
     5701 tatctggtac gtgaacgcga actgcaattt gccgatctcc agtcccgtct ggaaaaaggc
     5761 gaggatctgg aagccactat ccgtctgcgt gaggagctgg cagagcatcg tcatgcgctg
     5821 ttgcagattc aggaaatggc ggcgaaatat ggctttgata tctctcgccc ggcgcagaat
     5881 gcgcaggaag cggtgcagtg gctctacttc gcttatctgg cggcagtgaa atcgcaaaat
     5941 ggcggcgcga tgtcgctggg gcgcacggca tcgttcctcg atatctacat tgagcgcgac
     6001 tttaaagctg gcgtactcaa tgagcagcag gcacaggaac tgatcgatca cttcatcatg
     6061 aagatccgta tggtacgctt cctgcgtaca ccggaatttg attcgctgtt ctccggcgac
     6121 ccaatctggg cgacggaagt gatcggcggg atggggctgg acggtcgtac gctggtgacc
     6181 aaaaactcct tccgctattt gcacaccctg cacactatgg ggccggcacc ggaacctaac
     6241 ctgaccattc tttggtcgga agaattaccg attgccttca aaaaatatgc cgcgcaggtg
     6301 tcgatcgtca cctcttcctt gcagtatgaa aacgacgatc tgatgcgtac tgacttcaac
     6361 agcgacgatt acgcgattgc ctgctgcgtc agcccaatgg tgattggtaa gcaaatgcag
     6421 ttctttggtg cacgcgctaa cctggcgaaa acgctgctgt acgcaattaa cggcggggtg
     6481 gatgagaagc tgaagattca ggtcggtccg aaaacggcac cgctgatgga cgacgtgctg
     6541 gattacgaca aagtgatgga cagtctcgat cacttcatgg actggctggc ggtgcagtac
     6601 atcagtgcgc tgaatatcat tcactacatg cacgacaagt acagctacga agcttcgctg
     6661 atggcgctgc acgatcgtga tgtctatcgc actatggcat gcggcatcgc gggcctgtcg
     6721 gtggcgacgg actccctgtc tgccatcaaa tatgcccgcg tgaaaccaat ccgtgacgaa
     6781 aacggcctgg cggtggactt tgaaatcgac ggcgaatatc cgcagtacgg taacaacgac
     6841 gagcgcgtag acagcattgc ctgcgatctg gttgaacgct ttatgaagaa aattaaagcg
     6901 ctgccaacct atcgcaacgc cgtccctacc cagtcgattc tgactatcac ttctaacgtg
     6961 gtgtacggcc agaaaaccgg taatacgccg gacggtcgtc gcgccggaac accgttcgcg
     7021 ccgggcgcta acccgatgca cggtcgtgac cgcaaaggtg cggtagcctc gctgacgtcg
     7081 gtggcgaaac tgccgttcac ctacgccaaa gacgggatct cgtacacctt ctcgatcgtg
     7141 cctgcggcgc tgggcaaaga agatccagta cgtaaaacca accttgtcgg cctgctggat
     7201 gggtatttcc accacgaagc ggatgtcgaa ggcggtcaac acctcaacgt caacgtaatg
     7261 aatagggaaa tgctgctgga tgccatcgag cacccggaaa aatatcctaa cctgacaatc
     7321 cgtgtctctg gctacgccgt gcgcttcaac gcactgaccc gtgaacagca acaggatgtt
     7381 atttcacgta cttttaccca ggcgctctga cgccggagga tgtatgaaaa agattatcga
     7441 aacgcaacgt gccccaggcg caatcggccc ttatgttcag ggcgttgatt taggcagcat
     7501 ggtcttcacc tccgggcaaa ttccggtttg cccacagacc ggtgagatcc cggctgatgt
     7561 gcaagatcag gcgcgtttaa gcctcgaaaa cgtcaaagcg atcgtggttg ctgccgggct
     7621 gagcgtgggc gatatcatca agatgaccgt gttcatcacc gatctgaatg attttgccac
     7681 catcaacgaa gtctataagc agttcttcga tgagcatcag gcgacctacc cgacccggag
     7741 ctgtgtacag gtcgcgcgtt tgccgaaaga tgtgaagctg gaaattgaag ccatcgcagt
     7801 acgtagtgcg taaagcctcg tgagcgggac ggtcgcaagg tcgttccgct ccacttcact
     7861 gaacggcaat ccgagggtgt ggatatgatt agtgcattcg atattttcaa aattgggatt
     7921 ggtccctcca gttcgcatac cgtggggcca atgaatgccg gaaaaagttt tattgatcgg
     7981 ctggaaagta gcggcttatt aaccgcgacg agccatattg tggtcgatct gtacgggtcg
     8041 ttgtcactga cgggcaaagg ccatgccacg gatgtcgcca tcatcatggg actggcagga
     8101 aacagtccgc aggatgttgt cattgatgag atccctgcat ttatagagtt agtaacgcgc
     8161 agcgggcggc tgccagtggc atctggtgcg catattgttg attttcctgt agcaaagaac
     8221 attatcttcc atcccgaaat gttgcctcgc catgagaacg gaatgcggat cactgcctgg
     8281 aagggacagg aagcgctatt aagtaaaacc tattactctg tcggcggcgg gtttattgtc
     8341 gaagaagaac acttcggcct gtcgcacgat gtcgaaacgt ccgtacctta cgatttccac
     8401 tcagcaggtg aactgctgaa aatgtgtgat tacaacggcc tgtctatatc tggtctgatg
     8461 atgcacaacg agctggcgct gcgcagcaaa gcggaaattg acgcagggtt tgcccgtatc
     8521 tggcaagtga tgcatgacgg tattgaacgc gggatgaaca ctgaaggcgt gctgcctggt
     8581 ccgctcaatg tgccgcgtcg tgccgtagcg ctgcgtcgtc agctggtttc cagcgataac
     8641 atctctaacg atccgatgaa tgtcatcgac tggatcaata tgtacgcgct ggcggttagt
     8701 gaagaaaacg cagctggcgg gcgtgtggta acggcaccga ctaacggtgc gtgcggcatt
     8761 attccggcag tgctggctta ttacgataag ttccgtcgtc cggtaaacga gcggtcaatt
     8821 gcccgctatt ttctggccgc gggagctatt ggcgcgctgt ataaaatgaa cgcctccatc
     8881 tctggcgcgg aagtcggctg tcagggggag attggcgtgg cctgttcaat ggcggcggca
     8941 gggttaactg aactactggg cggcagtccg gcgcaggtat gcaatgcggc ggaaatcgcg
     9001 atggagcata accttgggct gacctgcgat ccggttgccg gacaggtaca aatcccgtgc
     9061 attgaacgta atgccattaa tgccgtgaaa gcagtaaatg ccgcacggat ggcgatgcgc
     9121 cgcacctcgg caccacgtgt ttcactcgat aaagtgatcg agacgatgta tgaaaccggc
     9181 aaagatatga acgataaata ccgcgaaaca tcacgcggag gactggccat taaagtggtc
     9241 tgcggctgac attactgtca gctttcatcc ttgggtgcac aaatgtgcac cttttttttg
     9301 tgatctgccg caaatagaga atgaatattc tcttgtgatt aatttagtag aaaattctta
     9361 tccatctccg ttatttcaaa gtcttgattg tgaagatttt ctctgacctc gcgcgtatca
     9421 tttctttatt ctaataactc gcctgcaaaa acgtagaccg catatcgcct tgatgcggct
     9481 cggaaaaaaa taataagccc tacaaaatat tgagcgagaa attatggaaa ttgcatcgaa
     9541 taaaggcgtc attgcagacg cttcgacccc ggcgggtcgt gctggaatga gtgagagcga
     9601 gtggcgagaa gcgatcaaat tcgacagtac tgacaccggc tgggtgatta tgagtatcgg
     9661 gatggcgatt ggcgcgggga ttgtttttct cccggtgcag gtcggtttga tgggattgtg
     9721 ggtatttttg ctctcatcgg tgattggtta cccggcaatg tatctgtttc agcgattgtt
     9781 tattaatacg ctggcagaat caccagaatg taaagattac ccgagtgtca ttagcggtta
     9841 tttaggtaaa aactggggca tcctgttagg tgcgctctat ttcgtaatgc tggtgatttg
     9901 gatgttcgtc tattccaccg ccatcaccaa cgatagtgct tcctacctgc ataccttcgg
     9961 cgtgacggaa gggttgctgt cagacagtcc cttttatggt ctggtactga tttgcattct
    10021 ggtggcgatc tcctcacgcg gcgagaaatt gttatttaaa atttcgaccg acatggtgct
    10081 gaccaagctg ctggtggtcg cggcgctggg cgtgtcgatg gtgggaatgt ggcatctgta
    10141 taacgtcggt tcgctaccgc cgctggggct gctggtgaaa aacgccatta ttacgctgcc
    10201 gtttaccctg acgtcgattc tgtttatcca gacgttaagc ccgatggtga tctcttatcg
    10261 ctcgcgggaa aaatcaattg aagtggcgcg gcataaagca ttgcgggcaa tgaatatcgc
    10321 gtttggcatt ttgtttgtca ccgtcttttt ctacgccgtg tcgttcacgc tggcgatggg
    10381 acatgacgaa gcggtaaaag cctacgagca gaatatttcc gcgttggcga ttgccgcaca
    10441 gtttattagc ggtgacggcg cagcgtgggt gaaagtggtc agcgtcattc tcaatatctt
    10501 tgctgtcatg actacattct ttggcgtcta tttaggcttt cgcgaagcaa cgcaagggat
    10561 cgtaatgaac atcctgcgtc gcaagatacc tgccgagaag attaacgaaa atctcgttca
    10621 gcgcggcatc atgattttcg ccattttgct ggcctggagc gccatcgtac tgaacgcccc
    10681 ggtgttgagc ttcacctcta tctgtagccc gattttcggc atggtagggt gcctgatccc
    10741 ggcgtggctg gtttacaaag taccggcatt gcacaaatac aaagggatgt ctctgtacct
    10801 gattatcgtc actggtttgt tgctttgtgt ttctccgttc ctggcatttt cttgatttac
    10861 ctgaaatttt aaggttttta atatgtttga ttcgacttta aatccgttat ggcagcgtta
    10921 catcctcgcc gttcaggagg aggtaaaacc ggcgctgggg tgtactgaac cgatttcact
    10981 ggcgctggcg gcggcggttg ctgcggcaga actggaaggt ccggttgaac gtgtagaagc
    11041 ctgggtttcg ccaaatctga tgaagaacgg tctgggcgtc accgttcccg gcacgggaat
    11101 ggtggggctg ccgattgcgg cggcgctggg agcgttaggt ggaaatgcta acgccgggct
    11161 ggaagtgctg aaagatgcaa ctgcgcaggc aattgccgat gccaaagcac tgctggcggc
    11221 ggggaaagtc tcagttaaga tccaggaacc ttgcgatgaa atcctcttct cacgcgccaa
    11281 agtctggaac ggtgagaagt gggcgtgtgt caccattgtc ggcgggcata ccaacattgt
    11341 gcatattgag acgcacaatg gtgtggtgtt tacccagcag gcgtgtgtga cagagggcga
    11401 gcaagagtcg ccgctgacgg tgctttccag gacgacgctg gctgagatcc tgaagttcgt
    11461 caatgaagtc ccgtttgcgg cgatccgctt tattctcgat tctgcgaagt taaattgtgc
    11521 gttatcgcag gaaggtttga gcggtaactg ggggctgcat attggtgcga cgctggaaaa
    11581 acagtgcgcg cgcggtttgc tggcgaaaga tctctcttca tccattgtga ttcgtaccag
    11641 cgcggcatcc gatgcgcgta tgggcggtgc tacgcttccg gcgatgagta attcaggctc
    11701 gggtaaccag gggatcactg caacaatgcc tgtggtggtg gtagcagaac acttcggggc
    11761 cgatgatgaa cggctggcgc gtgcgctgat gctttcgcat ttgagcgcga tttacatcca
    11821 taaccagtta ccgcgtttgt ctgcgctttg tgccgcaacg accgcagcaa tgggggccgc
    11881 cgccgggatg gcatggctgg tggatgggcg ttatgaaacc atttcgatgg cgatcagcag
    11941 tatgatcggc gatgtcagcg gcatgatttg cgatggagcg tcgaacagct gcgcgatgaa
    12001 ggtttcgacc agtgcttcgg ctgcgtggaa agcggtgtta atggcgctgg atgataccgc
    12061 agtgaccggc aatgaaggga ttgtggcgca tgatgttgag cagtcgattg ccaacctgtg
    12121 tgcgttagca agccattcga tgcagcaaac ggatcggcag attatcgaga ttatggcgag
    12181 caaggccaga taaacgccag gttttgggta tcgtgccgga tgcgatgctg gcgcatctta
    12241 tccggcctac gaattgcaca atttgttgat gttgttgggt tttgtaggcc ggataaggcg
    12301 tttacgccgc atccggcacc tgtctttacg cggtagcttc atcctcggct aaacgcgttt
    12361 cagcatccgc gacgatggct tccagctcgc tcaacatctc ttcatagcca aaattattgg
    12421 cggtgcgagc aggttctttc gccaccacgg gcttcactgg ctgacgcttt ttggccgatt
    12481 ttttactcat catcatctcc ctgtaaaaac aactagacag gcaaatctat cagcaaagcg
    12541 cgcagtgggg aatcggcaac cagcgtaatg ttagcctcgt cacgaataaa cgccccatca
    12601 ccgcaggtca gcgccgcttt ctcttcataa tgcgtaagcg catgaaattt cccgtgaatc
    12661 gattgcaaat acgcgcgtgg cccatgcaac tggaaattcg cactttcgcc tttgtcgagc
    12721 acgatatggt gcagccacac ttgctggcgc aattgcaggc ttcccatccc accttctggc
    12781 gaggcgatta attgctgctt gctcatatta agcgccagtt tttgaatcag cggattctct
    12841 cgttgtgggc aggcatccag ccaaagctgc attcgcgtta acggtttgtc tttgctgaga
    12901 ttgtgttcgc tatagctgac acccggctgg gtagagagca gcaacacctc accagtgctg
    12961 gtctgaacat gattgccttc gctgtcgcga tactcagctt ctccatccag aatcacattt
    13021 aaaatatcga ctttgggata ggttcgcggc tgaaaggcgg cacctggggc cagcacttcc
    13081 tggttaagca cgcgcaggga ggcatagcct aacaatttcg ggtcgaagta gtgtccaaag
    13141 gaaaaagtat accgggcctg caaccatccg tagtctgctt gtccacactg cctggcagtt
    13201 cgggtagtaa tcataattct tgacctctct ttacttcctt ttatggtaag gggctggacg
    13261 ctacattgtt agccagatat tctgcccggt atgttcaaat ttcctgaatg agaacgaaat
    13321 ggccaaagaa agggcattaa cgctggaagc actacgggtt atggatgcga tcgatcgccg
    13381 gggcagtttt gcggcggcgg cggatgagct gggacgcgtg ccttccgcac ttagctacac
    13441 catgcaaaaa ctggaagaag agcttgatgt ggtgctgttt gaccgctcgg gccatcgcac
    13501 caaattcacc aatgtcggga ggatgttgct ggagcgaggg cgcgttttgc tggaagccgc
    13561 agataaactg actaccgatg cggaagctct cgcgcgcggt tgggaaacgc atctcaccat
    13621 tgtgaccgaa gcgctggtac cgacacctgc ctttttcccg ttaattgaca aactggcggc
    13681 aaaagccaat acccaactgg caatcatcac cgaagtgctg gcgggggcgt gggaacgact
    13741 ggagcagggg cgggcggata tcgttatcgc gccggatatg cattttcgtt cctcgtcgga
    13801 gatcaactcg cgcaagctct atacgttaat gaacgtctac gttgccgcgc ctgatcaccc
    13861 gattcatcag gagccggaac cgttatctga agtgacgcgc gtgaaatatc gtggaattgc
    13921 ggtggcggat accgctcgtg agcgcccggt attgaccgta cagctactgg acaaacagcc
    13981 gcgtttaacg gtgagcacga ttgaagataa acgtcaggca ttactggcgg ggcttggcgt
    14041 ggcgacgatg ccgtatccga tggtcgaaaa agatatcgcg gaagggcggt tgcgtgtcgt
    14101 cagcccagaa tcgactagcg agatcgatat tattatggcc tggcgtcgtg acagtatggg
    14161 ggaagcgaaa tcctggtgtc tgcgggaaat tcccaaactt tttagcggaa aataatattt
    14221 gttattgtta ataaaaaggg gcgaaatatc gccccaattt taagattaat ttgaaccaaa
    14281 cttcggatcg tttccgtaac gattgctgcc agaattgccc tctaaacagg caaatacaaa
    14341 cagaactaac cagccaatga tcggtaccag atagagaagc gcccacgcac ctgaacggtc
    14401 agtatcatgc agacgacgaa cgcacagagc aatgaccgga atgattgttg ctgccaggta
    14461 aatgagagaa aggaacggaa actctaaacc taaaatcaat tgaatgacat tgataatagc
    14521 gccgacgatg gcgttaatca gagtaaacat ccagtactct ttacgacgtg cgcgaccaga
    14581 gaaaccaaca taatttttta atacggataa ataccactgc ataaaaacat ccctttaatt
    14641 aaaagtgacg aaagtttatt ccgggtattg tgtaaatgct attcgtatct ttctttttcg
    14701 gatgttataa aggttttgat atttaagata aatacatggt tattttttat atgtaattta
    14761 tataacgaca ttgaaatatt ttaaataaac attagtaaat tattcattca tcaacataat
    14821 gataaaagcc ggatgagtca gacatccggc gagtagattt gttttaaggt tccagttttg
    14881 gatcaggtcc aaagcggttt tcgcctggcg tacccgcctg gcagttaaag acgatgataa
    14941 taagccagcc gataaacggg attaagaata gcagtgccca ccacgccgag cggtcggtgt
    15001 cgtgcaggcg gcggaactga actgcccacc atggtaaaaa caccagaata ccgtagattg
    15061 tcgtcaggat gccttcgcca ccggcacgtt gccagcctaa cattttatcc agtagcccca
    15121 gcacgaacgt aaagatgatg ttgaccagaa taaacatcca gtactctttg cgccgcgcac
    15181 gaccccggaa accgacataa ttttttagta ctttcagata ccagtccatt tttgcctcaa
    15241 ttttgctcaa tcacttgttt ttaaagcagc aaattaagaa tagacgtgaa tgaaatggca
    15301 gtaaatatta tcgcgatgaa ttaataaggc gctgtgaagg ataagggcaa gcgcaaaatc
    15361 gccagatgcg ctacgcttat ctggcctacg cggtcattgt aacatattga atataaacgt
    15421 tttgtgggtt taataaggcg ttcacgccgc atccgacatg aacaacatgc acttagctaa
    15481 ttatcagagg cacctcgtaa ggtgcctttt tttaaccgaa gcgaacatct cgaccatgcg
    15541 gttcatcgag atcctgccac ggaccaattg aaataatccc cgtagggttg atggtcttat
    15601 ggctgcggaa gtagtgatta cggatgtgat cgaaattgac tgtttcggcg atccccggca
    15661 tctggtagat atcgcgcagg aagccataca gattcaggta atcgctgatg cggtgcttat
    15721 cacacttgaa gtgggtgaca tacaccggat caaaacgcac cagcgtggtc cacaggcgaa
    15781 tatcggcttc ggttagctgg ttgccggtca ggtaacgatg ctggcctaaa atctgctcca
    15841 gtcgcgccag cgattcaaac actttcacta ccgcctcgtc gtaggcttgc tggctggtgg
    15901 caaaaccggc tttatacacg ccattgttaa cggtgtcata aatccagccg ttaagttcgt
    15961 caattttcgt ttgcagggct ggtgggtagt aatcacccgc tttcgcgccc agcgcatcaa
    16021 acgcggtatt gaacatgcgg atgatttccg ctgattcgtt gctgacgatg gtgtggttct
    16081 ttttgtccca gagtacggga acagtaactc gtccgctgta gtgtggatcg gcgtggagat
    16141 aaagctgata cagaaattca tgttgataga gtgtatcgcc ggttgcaccc ggaaaactgt
    16201 catcaaaggt ccagccgttt tccagcatca gcgggttcac tacggaaacg gaaataaacg
    16261 gttccagtcc tttgagttta cgcatgatca gcgtgcggtg cgcccacggg caggcgagtg
    16321 aaacatagag atgataacga tctttctctg cgataaaacc gcctgtgcca gtggggcctg
    16381 gcgcgccatc ggcagtgagc cagttacgaa atgcggaagc tgaacgttga aatttaccgc
    16441 cggtagattt ggtatcgtac caggtgtcat gccagacgcc gtcaatcagt tgacccatat
    16501 ttctctcctc caatagcaaa aacgaggagc ttcctcctcg ttttttatcg ttaagtatag
    16561 cgcgtgctta ccacttttta ttcagcaggc ggtcgatgct atacgcgccc ggaccggtaa
    16621 ttgccagcag caggaatccg ccagaaattg tcaggttttt catgaacatc agcgagttga
    16681 cgccttcagc aaagttgctg tgaaataaaa atgccgtcag cagcgtaaag cccgcagtaa
    16741 acagggctgt ggtgcgagtc aggaaaccga acaggattgc cagaccacca ccaaactcaa
    16801 gcagaatcac cagcggcagc ataaagcctg ggacacccat cgcttccata tattgttggg
    16861 tacccgcgta gccagtaatt tttccccagc ctgcggtaat aaacagaatc ggcattaaaa
    16921 tgcgcgctac cagtacacca acatcttcta attttttcat catactctcc actgcgccac
    16981 tcaggctgct gattgttttt ttgtgcaagg gcgcggtatt agcgtcgttg ctgtcgatgg
    17041 agagaatcat aaacgtggtg aatgatgatt gttagcaagg aaaactgtca aaaatcttca
    17101 aaaaatttga gggataaggc cggaatggct ccggccagag aggttattaa ccgcgaagct
    17161 gttgctgctt gagggtcgtt ttaaccagac gccaggcgct ccataagcca aaaccgcgtc
    17221 tggcccagcg gaccagcata ttaggatggc gaatcgtcca gatcgccatc acgctactgc
    17281 caaccagcgc ccaggagcgc agacttagca gcatattcca gcgacgatcg taagcgcctg
    17341 ttgcctccag ccattcacga cgactggcag aaagatccag ccgttgttgc tggatctggc
    17401 taagcagttg cgccttacgt cgttcacgtt cgactttact gctcacggga ctcctcctcg
    17461 agcagctgcc gatcgtttgc cagctcatgg cgtgtatggc gcagcaaggt ggatttacgc
    17521 gatttacgta acgtccagat accgccaatc agtgccagta gcagcaacac cacggtggtg
    17581 gcaatcatcg cattcaggcg atattgcgga tcaaccgccc aaataatcag caccatcagg
    17641 ctcataagac caaatgcagc gaaaagcatc gtcaggccca gcatcagtaa aagttgaaag
    17701 agattcgctt tttcctcttc cagctccacc accgccagcc gcagacgtgt ttccaccatt
    17761 tcaaccatga tggaaacaat tcgctgcccg atgcccagaa cgcttttacc gggcccttgc
    17821 gcgtgatgag tgtccgccat aattaacgac gcgatagcag aacgccgagc actacaccga
    17881 ttgcagcgcc aatgcccacg cccgtccatg gattttcacg cacatactca tcggcacgcg
    17941 ccgccgcgac acgggtttgt ttggcgatgg catcaccggt ttcacccagg cgataacggc
    18001 tctgtttcag tgcctgctcc gctttgctac gaatcttact caactcttct ttcgacttct
    18061 cgccagatga gctaagcacc tcttccagcg tatcggaaag ggatttcaac tcagcacgca
    18121 gatgttccgt agtgtgttct ttcgacatag ttttctccag gtgagtaagt agtgactatt
    18181 gtgagttagt agtcgcgcgc ttccagcttt ttcagctctt cctgcgcttc tgccagtttc
    18241 cgttcgcgtt tggcaatctt atcggcatcg cctttttgct tcgcctcggt taaatcttgc
    18301 tggcgttccg ccacctcatc tttctgcttt gcgattttct tctgatgatc ggcacgcagc
    18361 tggctatctg aacagttggc ccggacttca ctcagggctt tattcagacc gtcaatacga
    18421 ttctggtttt ggtgtttttc ggcatagctg atctccttaa ggatattttg ctccttttcc
    18481 tgacacaggg tagtggcata actaccggca ctaagagcaa agagagaaac agctaaagcg
    18541 atgcggtatt tcattcttga accttccatt gtgattcgga cctattacaa aggaacgatt
    18601 gtccagacaa cgaagcggta gtgttaacca ccgcctcatt aatcatagac agttacggtg
    18661 aaatcaccaa agtcagtgat atgtttcgga taacaggaag ttatccgaag cgatgagagt
    18721 tatcccgcaa ccgggtcagc cactgcatag cctgactatt attgtcctgc tgcgcgatga
    18781 tgtagccatg gggcaatgtt ctgtcgagga ccgcttttgc ggcggcactc tggtcgctgg
    18841 agtcaaaggt aattaacaga gtgtcatttt tgggggtgat acttttgaaa ggaatgccgt
    18901 gagcgtcaag gtgatgccag attgaaaaac cgtctggcat cgttgtccct tgatgaacgg
    18961 cacgaatcgc cagcgtagac tcttgctggc gaaccgcgga ccaggccagc aacagtgtgc
    19021 cgaccagaag taaaacagcg ccggaccagg ctagctggcg aagcgacatg cgaggtattt
    19081 gcatccctta cccccgattt ccatatttct ttttccataa cacgaccaga gaacctgcca
    19141 ggccaaacac cagcagcacc accgggagca gcatcaggca tgacatcagc tggtcctcgt
    19201 actttaaaaa taccggcgtt ttgccgagca tgtaacccag agttgtcagg atcaataccc
    19261 acagcagacc gctcatccag ttgaagaact gaaagcgcgc gttattcagc cctgataatc
    19321 cggcaatcgt cggcagtagt gttctgacaa atgcaataaa gcgaccaatt aacagcgccg
    19381 ataaaccgtg tttatgaaaa agatggtgtg cgcgttgatg ataatgcgcg ggtaaatgag
    19441 atagccagtt ttgtactgtg cgggtattgc ccagccatcg cccctgaata tagctgaccc
    19501 agcaaccgag gctggcggca acggtcagca gcagaatcgt ttgcggatag cccatcgcgc
    19561 ctttcgcaat caatacgccg accaacacca gtaaactgtc gcccggtaaa aaggccgccg
    19621 gaagcaagcc gttttcaagg aacaaaatta caaacaagac aaaatacaac atgccaatca
    19681 tcgacggatt ggccagggtt tcaaaatcct gcgcccacag ggcttgcagc aattgggtca
    19741 aaagttccat tcattattcc tggtgaatcg gttaacgcca cgctggtttt aaaagatgca
    19801 ctaccgcaat gttattgctg ttttggtatg ttttgcgggt ttgatacatc aacacagcct
    19861 gaactattcc ctgttaaatc gtgagataag aaagcattca aaagcataaa ttcaaattga
    19921 atctaattgt aacaaaggtc aacgttgttc gttatcaaaa ttacatgtcc gtagagtctg
    19981 attttgctga ttgcagggga gggtggcgag aggatttaca caggctgaca ctttatactt
    20041 ttcgcttacc gacgaagcaa acaggcgcat tgcagcgcct gtcggatgga aatttcattt
    20101 gctgccgctg gtggccgtat cgagatgcac aaccgggttt tctgcgaaca gatagcggtc
    20161 ggcattgaac tcgaaatcgt cgctggtttc gttaaataac atgattttgg tgttttccag
    20221 atgctgccac attgccagct tagcagcatg aggatctttg cgaatcagcg ccttgaggat
    20281 ttgatcgtgg tcatcacacc agttatcgac ggtacgggca tcaatgtgtt cgtgcagttt
    20341 tttccagtac gggttatgac tacgctgggt ccacattttt tcaacgatag ccgccagggc
    20401 ggagttctgc gtcgccaggg ctacctgaat gtggaactgc aaatcccact cggaatcacg
    20461 gaagcattgt tcgccgcgcg cctgctcctg gatggccatc agtttcatga tgtcctgttt
    20521 cgttacctga gttgccgcga attcggcaat attactttcg atgagctggc gagcctgaag
    20581 caactcaaac ggaccgtaat tggcgaattc catattattg tcagccgcct gctgatggcg
    20641 cggctggttg gaaaccacat gaatacctga acctttacgc acttcgacat agccttcaac
    20701 ttccagcatg atgatggctt cacgaaccac ggtgcggctg acgttttttt catcggcaat
    20761 aaagcgctca gcaggcagtt tatcacccac cagatagacg ccctgttcga tgcgctcttt
    20821 cagatcagcg gcaagttgtt gatacaaacg gcgtggttca gtgatttcca tatgcgctcc
    20881 aggcatgata cggcagacta tatttgttat accacttttg cgagtttagc tctactcaca
    20941 gtgatgaaaa agccgcctga gaaggcggct ttgaagggaa actaaaactt acacgaagcc
    21001 ttaatgttgc ggtgcgggat cgttatgtga ttcctgcgcc acctcaatcg ccggtttgtt
    21061 ctgcaacacg gtccagataa ccagtgcacc taacaggtcg aacactgcca gaactgcgaa
    21121 cagcgggctg aagccgatgg tgtcagccag tgcaccgact accagtgcaa acagcgtact
    21181 tgccagccat gcggacatcc cggttaaacc gttcgccgtc gccacttcgt tacgaccgaa
    21241 cacgtcagaa gagagcgtaa tcagcgcgcc agacagtgcc tggtgagcaa aaccaccgat
    21301 acacagcagc ataatcgcga catacgggtt ggtgaacaga ccgatcatac ccgggccaat
    21361 catcagcaca gcacccagcg ttacgaccat cttacgggaa acgatcaggt tcacaccaaa
    21421 ccaacgctgg aacagcggcg gcaggtaacc accgaggata caaccgaggt cagcaaatag
    21481 catcggcatc caggcaaaca tcgcgatctc tttcaggtta aagccgtaaa ctttaaacat
    21541 gaacagcggg atccacgcgt taaaagtacc ccatgccggt tctgccagga agcgcggcag
    21601 cgcgataccc cagaactgac ggttacgcag gatctgacca acggacattt tcttcgctgt
    21661 gtcaacctgg tgctgggctt cctgaccatt aataatgtag tcgcgttctt catcggtcag
    21721 atgcttctgg tcgcgcggat gtttatagaa aatcagccat gccattgccc agataaagct
    21781 caacgcaccg gagatgataa atgccatctg ccagctgtgc attacgattg cccataccac
    21841 cagcggcggt gcaatcatcg caccaataga agaacctacg ttaaagtaac ctaccgcgat
    21901 ggaacgctct ttcgccggga accattcgga gctggctttc agacccgccg ggatcatcgc
    21961 tgcttccgcg gcaccgaccg caccacgagc aacagccagg ccgccccagc tacctgccag
    22021 cgcggttgca ccacagaaca cggcccacag cacagcaaac attgcataac cgattttcgt
    22081 acccagcaca tccagtacat aacctgctac cggttgcatg accgtataag cagcagaata
    22141 ggctgcgatg atataggaat actgttgggt ggagatgttt aactcttcca tcagagttgg
    22201 cgcagctgcc gccacagtgt tacgcgtcag gtaaccaagc acggtgccga gcgtcaccag
    22261 tgcgatcata taccaacgta accctttaat tttacgcatg taaaacctca tcgttttgtt
    22321 atatccgcag gaagcgcggc catcatcccg ccagaggctg aagatgttag ttacgaccgg
    22381 gtaaccgaaa aaaaaccggc acgccccgaa cgttgccatg aaagtttcgt gctaattcgg
    22441 cttccgtacc ggttaacccg attcatctaa caaatgaatg aatcggcaat ttgcattccg
    22501 tcgacttatg atttgcgacg gcagaaagat aacttgtcat acaactttaa aaggtgagag
    22561 ccatcacaaa tgtgggaata tttgtaggga cattacctga cgacagcgag gccagtactg
    22621 gcgcggcctg cagcgagatt taccactttg agagtaattt ttttaactac gtttattgat
    22681 ctatctcacg aaaatatctt cggactctgg aaattggtgt gataactttg tcagcatcgc
    22741 accataagca agctagctca ctcgttgaga ggaagacgaa aatgactccg tttatgactg
    22801 aagatttcct gttagatacc gaatttgccc gccgtctgta tcacgactac gcaaaagacc
    22861 agccgatttt cgattaccat tgccatttgc cgccgcagca gattgcggaa gactatcgtt
    22921 ttaaaaacct gtatgacatc tggctgaaag gcgatcacta caaatggcgt gctatgcgta
    22981 ccaacggtgt ggccgagcgt ctgtgtaccg gtgatgcgtc tgaccgtgaa aaatttgacg
    23041 cctgggcggc gactgttccg cacactatcg gcaacccgtt ataccactgg acgcatcttg
    23101 aactgcgtcg tccattcggt atcactggca aattgctttc tccgtcaact gccgatgaaa
    23161 tctggaacga atgtaacgaa ctgttggcgc aggataactt ctccgcgcgc ggcatcatgc
    23221 agcagatgaa cgtgaaaatg gtcggcacga ccgatgaccc gatcgattct ctggagcatc
    23281 acgcagagat cgccaaagac ggctctttca ccatcaaagt gctgccgagc tggcgtcctg
    23341 ataaagcctt caacatcgaa caggcgacct ttaacgacta catggcgaag ctgggcgaag
    23401 tttccgatac cgacatccgc cgctttgctg atctgcaaac tgccctgacc aaacgtctgg
    23461 atcacttcgc cgctcacggc tgtaaagtgt ctgaccacgc gctggatgtg gtgatgtttg
    23521 ctgaagcgaa cgaagcggaa ctggacagca ttctggcgcg tcgtctggct ggcgaaaccc
    23581 tgagcgagca cgaagtggca cagttcaaaa ctgcggtgct ggtgttcctt ggtgccgaat
    23641 atgcacgtcg cggctgggta cagcagtacc acattggcgc actgcgtaat aacaacctgc
    23701 gtcagtttaa actgctgggg ccggatgtcg gctttgactc catcaacgac cgtccgatgg
    23761 cggaagagct gtctaagctg ctgagcaagc agaacgaaga aaacctgcta ccgaaaacca
    23821 ttctctactg cctgaacccg cgcgataacg aagtgctggg caccatgatc ggtaacttcc
    23881 agggcgaagg tatgccgggc aaaatgcagt tcggttccgg ctggtggttt aacgatcaga
    23941 aagacggtat ggaacgtcag atgacccaac tggcgcagct cggtctgttg agccgctttg
    24001 tcggtatgct gactgacagc cgtagcttcc tgtcatacac ccgtcacgaa tacttccgcc
    24061 gcattctgtg ccagatgatc ggtcgctggg tggaagcggg cgaagcaccg gcggatatca
    24121 acctgctggg cgagatggtg aaaaatattt gctttaacaa tgcgcgtgac tacttcgcca
    24181 ttgaactgaa ctaaggtctg gggttgatat gcaatacatc aagatccatg cgctggataa
    24241 cgtcgcggtc gctttagcgg atttggctga aggcacagaa gtcagtgtcg ataaccagac
    24301 tgttacgctg cgccaggatg ttgctcgtgg acataaattt gcgttaacgg atatcgcaaa
    24361 aggggccaac gtcatcaaat atggcctgcc gattggttat gcattggcgg atattgcggc
    24421 gggggaacac gtccacgccc acaatacgcg cacgaatctg agcgatttgg atcagtatcg
    24481 ctatcaacct gattttcagg atctgcctgc gcaagcggca gatcgtgaag tgcagatcta
    24541 tcgtcgcgct aacggcgatg tcggggtgcg caatgagctc tggatcctgc caaccgtggg
    24601 ctgtgttaac ggcatcgcgc ggcagatcca gaaccgtttc ctgaaagaga ccaacaacgc
    24661 cgaaggtact gacggcgtat tcctcttcag ccacacctac ggctgctcgc agctgggcga
    24721 cgatcacatc aatacccgca ccatgctgca aaatatggtg cgccacccga acgcgggcgc
    24781 agtgctggtg attggcctgg gttgtgaaaa caaccaggtt gccgcattcc gtgaaacgct
    24841 gggcgatatc gatcctgaac gcgttcattt catgatctgc caacagcagg atgatgagat
    24901 cgaagccggg atcgagcatc tgcatcagct gtataacgtg atgcgcaacg acaagcgcga
    24961 gccaggcaaa ctcagcgaac tgaagtttgg tctggagtgc ggtggttctg acggtctttc
    25021 tggtattact gctaacccga tgctggggcg tttctctgac tacgtgattg ctaacggcgg
    25081 tactaccgta ctgaccgaag tgccggagat gtttggcgca gagcagttgc tgatggacca
    25141 ttgtcgtgac gaagcaacgt ttgaaaaact ggtcaccatg gtcaatgact tcaagcagta
    25201 ctttattgcc catgaccagc cgatttacga aaacccatca ccggggaaca aagcgggtgg
    25261 tatcaccacg ctggaagaca aatcacttgg ctgtacccag aaagccggtt ccagtgtcgt
    25321 ggttgacgtg ctgcgttacg gcgagcgtct gaaaacgccg gggctgaact tgttaagtgc
    25381 gccaggtaac gatgccgtag cgaccagcgc cctggcgggt gcgggctgcc atatggtgct
    25441 gttcagtact ggtcgcggca cgccatacgg cggctttgta ccgacggtga aaatcgccac
    25501 caacagcgaa ctggcggcga agaaaaaaca ctggatcgac tttgacgcgg gtcagttgat
    25561 ccacggtaaa gcgatgccgc agttgctgga agaattcatc gataccatcg ttgagtttgc
    25621 caacggtaag caaacctgta acgagcgtaa cgacttccgc gaactggcga tcttcaaaag
    25681 cggcgtaacg ctataaagtc gaaatgagtt gttaataaaa aacggcgttt cataatgtga
    25741 agcgccgttt gcttttccat acctgctaag gatttatcat gaccgcgtat tggctggccc
    25801 agggcgtggg tgtcatcgcc tttctgattg gtatcacaac atttttcaat cgtgacgaac
    25861 gtcgcttcaa aaagcagctt tcggtctata gcgccgttat tggcgtacat ttttttcttc
    25921 tgggcaccta tcccgctggt gccagtgcca tccttaatgc cattcgtaca ttgattacct
    25981 tacgcacgcg cagcttatgg gtaatggcga tttttattgt gctgactggc ggaattggcc
    26041 tcgcgaagtt ccatcatcct gtcgaactat tgccggttat cggcacgatt gtcagtacct
    26101 gggcgctgtt tcgctgtaaa gggctgacca tgcgctgcgt gatgtggttt tcaacgtgtt
    26161 gctgggtgat tcacaacttc tgggcggggt cgataggcgg cacgatgatt gaggggagtt
    26221 ttctgcttat gaatggcctg aatatcattc gtttctggcg gatgcagaaa agggggattg
    26281 atccgtttaa agtagagaaa accccttccg ccgtagacga aaggggttaa acaattaatt
    26341 acgcagggcg ctatttgcca gacgatcgtc ttccgcctgg caagctgccg cagtgaacag
    26401 cacgtcagtt gaagagttca gcgcggtttc gcaagagtcc tgcaatacgc cgatgataaa
    26461 gccgacggca accacctgca tggcgatatc gttcgaaata ccgaacatat tacaggccag
    26521 cgggatcagc agcagagaac cccccgccac gccggatgcg ccacaggcac acagagaagc
    26581 cacaacgctc aacagcagcg ctgtgggcag atcgaccgga atacccagcg tattaactgc
    26641 agccagcgtc aacacggtaa tggtgattgc tgcgcccgcc atattgatgg tggcacccag
    26701 cggaatagaa acggaatagg tatcgcgatc cagattcagc ttttcacaca gcgccatatt
    26761 caccggaatg ttcgctgcag agctgcgggt gaagaaggca tacacaccgc tttcacgcag
    26821 gcacagcagc accagcggga acgggttacg acgaattttc caccacacca gcaatgggtt
    26881 aaccaccagc gccaccagta acatacagcc aaccagcacg accagcagtt gcgcgtagcc
    26941 ccacagtgtg gagaaaccgg tggttgccag ggtagaagaa accagaccaa aaataccgat
    27001 cggtgcgaag cgaatgacca gtttcaccat aaaggtgacg gcattcgaca tatcgttgac
    27061 caggtttttg gtggtctcgt taccgtgacg cagtgcgaaa ccgaggccaa ttgcccacac
    27121 cagaatcccg atgtagttac ctttcagcag cgcgtcgatg gggttggaaa ccatgctcat
    27181 taccagcccg cgcatcactt cgacaatgcc tgacggcggc gaaatatcac ccgcgctact
    27241 ggacaagtgc agggtagaag ggaaggcaaa gctgaagact actgcggcca gagcagcaga
    27301 gaaggtgccc agtagataga ggaacaaaat aggacggata ttggttttct gcccgtgctg
    27361 gtggttagca atagacgcca ttaccagcat caacaccagg atgggggcaa cggctttcag
    27421 tgcgccgacg aacaaagtac ctaacagacc aacagcttcc gccgcgggtt ttgagatcca
    27481 tgccagaaga atccccagaa caaggccgac caggatttgt tttaccaggc tgccatgagc
    27541 cagacgccgg aatagccccg gtgaacgttg cgtagtcatt tttcgatcct ttcattgtgt
    27601 tgtcgcacat ccctggtgcg ttctgtcgac gcatctttca ggatgtaaca aagtgtttgc
    27661 aaggtcgagt ataaggaaag ttacagcttc gggaagcgaa aaatgctgga ttttaaagag
    27721 aggtcatatt ttgcaactta atggttacat ttatttgaca taaacagagg gaaggactgg
    27781 ctactaaggc tgattagata acatatgggc aaaactattt ggaatatgag aacggttgcg
    27841 ctcctttaat gtgctatgcc atataaagtc aatgccgcag ggagcgcgca gggggcggcc
    27901 aatcgccgcc gccccctgca cccccaggct ctggcgaaca aaatcgccgc tgcgcggttc
    27961 cctcagctta tcccttgcgg ctaccgggtc gggcgcaagg gaacgtccct gtaagatgcg
    28021 ccctcgccgc gcatccatgc gcgtcgcccc ggcctccagg gaacgcttcg gcgattttga
    28081 cgccaccaac acccgtgcgg tctttttgta aagagctata agccgattac ataattaata
    28141 gctcaccttt gtctggaatg agttatctct agtaatggct taatatacag cgaatcattc
    28201 tccccgctgc ttatcatgcc gataattcac ccaggcgttg ataataaacg tcatcaccag
    28261 aatgccaaac accacgccca gcgagacggc gattggaata tggtagaagt cgacaatcag
    28321 catcttgata ccgataaaca ccagaatcac cgccaggcca tatttgagca tcgagaaacg
    28381 ttctgctacg cccgccagca ggaaatacat cgcacgcagg ccgaggatcg caaacaggtt
    28441 tgaggtcagc acaatgaacg ggtcagtggt cacggcgaag atagccggaa tgctatccac
    28501 ggcgaaaatc acgtcgctca attccaccag aatcagcacc agcatcagcg gcgtggcata
    28561 cagcaagcca tttttacgca caaagaaatg ctcgttgtcg atggtgtcgg tcatacgcaa
    28621 atgaccgcgc agccagcgca ccagcggctt gtcgccaatg cctgattcat cttcatgggc
    28681 cagcgccatc ttcacgccgg taaacagcag gaaggcaccg aagatataca ggatccagtc
    28741 gaactgcgaa atcagccagc tgccagtgaa gatcatgatg gtacgcagaa caatcgcccc
    28801 gagcacgcca tacaccagca cgcggcgttg taatgccgcc ggaacagaga aatagctgaa
    28861 caacatcagc cagacaaaga cgttatcgac cgccagcgat ttctcaatca gataacccgt
    28921 gagaaaggcc agtgcctgtg gatcggcaac ggcgcgacct tcggtttgca ccagatacca
    28981 ccagaaagcg gcgttaaaca gtaacgacag cgtcacccag accagcgacc aggccgcagc
    29041 ctgtttcatg gtcatggcat gtgccccacg acgcccctgc aacaacaggt cgatagccag
    29101 cataatggcg acaacaacag cgaatccgcc ccatagcaac ggcgtgccga cagtattcat
    29161 agaagttcct tacacataaa aaaaacggcc aacgtcggaa gacgtcagcc gctgcttttt
    29221 atgcatagac ctcgccttcc ggcaaggtct cacttacaac aaaaaaggaa tacgtctgcg
    29281 tattcctttc gggttgcccg gtgaccggat gtggtttttc acacatcgta atgacgatcg
    29341 accggcaatg aagttactcc cctttgcagg taacaaagta tgacagacca ttcagccagt
    29401 caatggtctg ttacatacct tttacactgt tttactttgg caattatagt tttacgctat
    29461 ctgctggaaa aatcacccca gtctggcggc ggatctcggt cagcagtttg gcggtgatgc
    29521 gactgaccgt cagccctgga tgatccacca gatgctcatc caccagttca gcaaacagct
    29581 ctgcttcgta gagcatggta ttaatatgct gcggctgggt gagatcctgc atctggctgc
    29641 cacgcggcac aaagcagact ttctggcatt cagacagttt ttcaatcacc agcgatcctg
    29701 cttcgccctg aatctcgctt gccaggacag aatcactcac ttttgagtgc tgcaaggtga
    29761 cgctgaaatc accgtaatcc atcaccacca cgccgtgggc atctacgccg cttgccaaca
    29821 aactggcggt tgcctgcacg cttttcggtt caccaaataa cgctaccgcc gacgccaggc
    29881 agtaaaagcc gatatccata atcgaaccgt tagagaatgc tggattaaag gtgttgggat
    29941 tctcaccgtc caggtaacgt tgataccgcg aggaatactg gcaatagttg aaaaagactt
    30001 tacgcagttt gccgactttc ggcagtgcct ggcgtaacag atgaaagttc ggcaggtagg
    30061 ccgttttaaa tgcctcaaac agcaccacct gattttcccg cgcacaggca atggcggcat
    30121 ccacttccgc cagattcgat gccagcggct tctcgcaaat cacatgaatt ttgtggctaa
    30181 ggaaaagttg tgtctgggaa aagtgcaggg cattcgggct ggcaatatac accgcgtcaa
    30241 tggcatcgct ttccgccatc gcttccagcg acgtaaacag atgctcgaca gaaaaatcat
    30301 tggcaaagtg ctgggcctgt tcaaggctgc gggaatatac ggcggttaac ttgtatttac
    30361 cgctctcatg ggcggcctcg acgaactggc gagtgatcca gttcgtacca atcacagcga
    30421 aacgtatcat aacgcgtgga tactccataa agggattctg tcgtcaatgt agcacgcctt
    30481 tttcatcttc gacgtgcgca gatacgcatt attctttcgc cggacagcca tgctcactaa
    30541 acggcccaat catgaccgat ggcccgagat atttcggctg gcgatggagg atttttgcgt
    30601 caatcaccgc gctgactctg gcgagtttct cccgtaactg agtataaaaa ccgtgcttca
    30661 tattgaggtc tggcgcgtta aagccgatag cgtcgatgcc gtactgtttt gccagccaga
    30721 tggcgcgttg gttatgaaat tcttgcgaaa taatggtgat atggttttcc ccaaacacct
    30781 ttttggcacg cactaccgaa tccagcgttg agaatccggc atagtcgcag aagatcactt
    30841 tcgccggtac gcctttagcg atcaaagcct gctgcatacc tgaggcttca tcgtaatttt
    30901 tacgtccgtt atcgccactt accagtagcc atttcacttt tccggcgtgg tacaacgctg
    30961 ctgcggtatc aatacgtcgg gtaaagtagc gattacccgg cctcgccccc agcaataaac
    31021 ccacgttacg cgccggaact gcgttgacat cgctccaggt cagctgcttg ctggtgttga
    31081 ccataacgcg atcggcaata aaaagggtcg ctcctgctgt aagcaacaat aaacagccaa
    31141 tcttaagagt ccggcgagaa aaacaaatac ggagaagaag gcgggcaaag gcgcgcagca
    31201 tggtcgttat ccttaacgaa aggggggagg tcgattttag gcgctaaagg aagaaaagat
    31261 aacgcctgac atcattttca gattttgtcc tgcccaagtg acaactgcgt tagccacaga
    31321 cgagtgtcga attcaagctg gtggtactgc ggctccatat gacagcacaa ttgatagaac
    31381 gctttgttat gctctttctc cttcaggtgc gccaactcgt gcaccacgat catgcgcaaa
    31441 aacggttccg gcgcgttgcg aaacacggta gcgacgcgga tctccgcctt tgctttcagc
    31501 ttaccgccct gcacacgcga aatagcggta tgtaacccga gcgcgttttt cagcacatgg
    31561 atcttattgt catacatcac tttagtgatc ggcggggcat tgcgcagaaa ctgatttttc
    31621 agatcctggg tatattgcca gagggcttta tcggtggcgt agtcgtgtgt tcccggatag
    31681 cgttttgcca gcacatcgcc cagacgctgt tcgttaatca gcgttcgcac ctgggaaagt
    31741 agctggtcgg gataaccctg aagataagta agattgctca taaccgccca cgaaaaagag
    31801 aaaaagggta tactcacgca cccttttcag gggcaacgtc gaaattttat cattcaggag
    31861 ggccgatgag ccacttagac aacggtttcc gttcactgac actacaacgt tttccggcga
    31921 cggatgacgt taacccgcta caggcgtggg aagcggcgga tgaatatttg ctgcaacagt
    31981 tggacgacac agaaatccgc ggcccggtgt tgatcctgaa tgatgccttt ggtgcgttaa
    32041 gttgtgcact ggcggaacat aagccttaca gcattggcga ctcatacatc agcgaactgg
    32101 cgacgcgcga gaatttacgc ctcaacggga ttgatgaatc gagcgtgaag tttctcgaca
    32161 gcaccgctga ctacccgcaa cagccgggcg tggtactgat caaagtaccg aaaacactgg
    32221 cgttgctgga acaacaactg cgtgcgctgc gcaaagtggt cacgccggat acacgtatta
    32281 ttgccggtgc caaagcccgt gacatccaca cttccacgct ggaactgttc gaaaaagtgc
    32341 tcggcccgac caccaccacg ctggcatgga agaaggcacg cttaattaac tgtactttca
    32401 acgagccgcc gctggccgat gcgccgcaga ccgttagctg gaaactggaa ggtactgact
    32461 ggactatcca caaccatgcg aatgtcttct cccgcaccgg gctggatatt ggcgcgcgct
    32521 tctttatgca gcatctgcca gagaatctcg aaggtgagat tgtcgatctc ggttgtggta
    32581 atggcgttat tggtctgacg ctgcttgata aaaacccgca ggcgaaagtg gtgtttgtcg
    32641 atgaatcgcc gatggcggtt gcttccagcc gtttgaacgt tgaaaccaac atgccagagg
    32701 cgttggatcg ctgcgagttt atgatcaaca acgcgctctc cggcgtggag cctttccgct
    32761 ttaatgctgt gctctgcaac ccgccgtttc atcagcaaca tgcgctgacc gataacgtcg
    32821 cctgggagat gttccaccac gcccgccgct gtctgaaaat caacggcgag ctgtatatcg
    32881 ttgccaaccg tcacctggat tacttccata aactgaagaa gattttcggc aactgcacca
    32941 ccatcgccac gaataataaa tttgtggtgc tgaaagcagt gaagctgggg cgtcgtcggt
    33001 aagattggca gctacctgcc agataaggcg taaacgcctt atctggcata cgttcagcac
    33061 attaccccca ggtcggataa gacgcggcaa gcgtcgcatc cggcacttca atgcacgatt
    33121 taaatctcca gcgccagccg tgttccctgg gcaattgccc gtcgtgcgtc cagctccata
    33181 gctacatcgc agccgccaat taaatgcaca gttttcccgc tatcaatcag cggttgcgcc
    33241 agcgcgcggt ttggctcttg ccctgcgcag atcaccacat tgtccactgc taatacctgc
    33301 gtttcgccgt tgatcaccac atgcagcccg tcatcgtcga tcttctgata acttacgcct
    33361 gggatcattt tcacgccgcg cgagagcagg gtggtgcgat ggatccagcc ggtggttttg
    33421 cctaacccct gtcccggttt gctggctttg cgctggagca tcacaatctg ccgtgggcta
    33481 cgcgggatct gcattccctg cgggcttaag ccaccagcct gttgcaggct gctgtcgatc
    33541 ccccactcat tacagaactc ggcaatgttc ttgctggtgg actcacccgg ctgacttaaa
    33601 aacatcgccg tatcaaaacc aatcccgcca caaccgatga ttgctacctt tttgcccaca
    33661 ggcgctttgt cgcgcagtac gtcgagataa ctcaacacct tcggatgatc gattccgtcg
    33721 ataggtggaa tgcgcggtac gatcccgcta gcgaggatcg tttcatcgaa cgactgtaac
    33781 tgatccgccg tcacggtgtg attgagtttc agcgtcacgc ctgttacttc gatcatccgg
    33841 cggtaatagc gcagcgtttc gtaaaactcc tctttgccag ggatctgttt ggcgatatta
    33901 aactgaccgc cgatctcact gtgagcatca aacaacgtta cctgatgacc acgtgccgcc
    33961 gcgttaatgg caaacgccag cccagccgga ccagcgccga ccaccgccag attttttttc
    34021 tgcacggcgg gaaggatcgg cattttggtt tcgtggcagg cgcgaggatt caccaggcac
    34081 gaggtgactt tgccaacgaa gatctgatcg aggcaggctt gattgcagcc aatacaggtg
    34141 ttgatctcat cggctcgccc cgattgcgct tttgacagca gttccgcatc agcaagaaac
    34201 ggtcgcgcca tcgataccat atcggcatca ccgcgcgaga gaatgtcgtc ggcaacctgc
    34261 ggatcgttaa tccggttggt ggtcaccagc ggtagcgaga cgtggccttt cagtttgcgc
    34321 gtgacccagc taaatgcgcc gcgcggcacg ggcgtggcga tggtcggaat acgcgcttca
    34381 tgccagccaa tgccagtatt aataatggtt gcgcccgccg cttcgatggc ctgcgccagt
    34441 tctaccgttt cggcaaaagt accgccgcct tcgaccaggt cgagcatcga cagacggtag
    34501 ataataatga agtcattgcc gacgcgttcg cgcactgctc gcaccacttc aactgcaaag
    34561 cgcatccggt tagggtaatc gccgccccac tggtcgttac gctggttagt gcgcagggtc
    34621 agaaattcgt tgatcaaata cccttcggaa cccatcacct ctacgccatc gtatccggcc
    34681 tcccgcgcca gttgcgcgca gcgggcgaaa ttgtcgatca gttgcaggat ctcttcatgg
    34741 cttaactcat ggggcacgaa acggttgatg ggagcctgca atgcggaagg agcgaccaga
    34801 tgcggttggt agctgtagcg cccggtatgc aaaatttgca gggcgatttt gccgccttcc
    34861 tgatgtacgg cttcggttat ggtgcgatgg tgcgggatct ggcttgcgtc attgagcatt
    34921 gcgccgcctt ccatgccaac gcctgttaaa tctggtgcaa taccgccgct gacaatcaac
    34981 gccacgccat gacgggcgcg ttccgcgtaa aacgctgcca gccgttcagc gccgtccggg
    35041 tattcctcca gtcccgtgtg cattgaaccc atcagtactc ggttttttaa cgtggtgaag
    35101 cctaaatcca gcggggcgaa cagcgacggg tagctcataa aattgtccag tatgtaaaat
    35161 aattgttatg tggtcggatg agttctaatt tagccgtcgc cggagaaaag ggaaaagggg
    35221 agtgcggggt ttgtgatggg attcaaaaag aatacgcccg gtggtaacgc cggatgcaac
    35281 gcttgccgcg ttttatccgg cctgggggat tgcacatgta gggcggataa ggcgtttacg
    35341 ccgcatccgc cagccattgc aaattactgc ttacggaaaa aatcgttata caacatatac
    35401 aaatgcgcgg cactccagga gaaattgggt gctccttgct gcgcgccagt gagcgggttg
    35461 taattctcct gaatcggacc atcggcggtt aatcctttgg cgtgctggaa gaacgtatcc
    35521 gccagcttca gggcatcatc gcgataaccg taacgctcca tccctttcag accaaaccag
    35581 aactgatcca cccacacgcg cccgcgccag taaatatctg cgccaaaggc cggattggtt
    35641 aacgccgccg ttcccagcgg aacaaaggtg ttgaactctt taggatcgag catcaccttc
    35701 accaccgcgt cggcgttggc ctgcgttgct gcaccgttaa acagcggtga ccagccttct
    35761 ggccctttac cgcgctcgac aatcggtttg cccgcgcagc cgttcgccag tggtttatct
    35821 tcaatgcgca cgtcatagta gaattgtgta gtcgggtcga acatacaggt gttgatgtag
    35881 tccgcgagct gctgtgccaa ctggcgatag cgttgggcct cttccggctt accgagtatg
    35941 gttgccatct ccgccagata atggttatcg ctgtacatat agctggcctg atccaccgac
    36001 tcctgcaata gcgagtagcc cagcaacgtt ccgtcctgac tgcggttttc ggcgaatttc
    36061 accgtccagt cgctacgttt gccgccatta gcgacatatt tatccagctg ttctttgtcg
    36121 ataaacccaa agacggcggc gtcatcacga cctgattccc acgacgcagc aacctgtgcc
    36181 ggaatttcca gactgtcgta ctggcctttc tccaccacac gggcgtagtt gttcagccca
    36241 gactgcgtct cttctttgtc gccttttttc accgtaaaca gcatctcgcc gctctcggtg
    36301 ttgtgggctt tgtcgcgggt cgcgccatat tccggcacgc cgttgccgtt gtgatcgcgg
    36361 ttacgtaacc accagtcgtg ataggccacc agcttcgggt acatctctgc caaccaggct
    36421 ttatcctggg tgacgttgta cacttccatc accgaccagg cggcaaggct gggtttggta
    36481 ttacgttcgt tccagttgcc gccatcgccg ccacgctcgg ggctaaggtt ccacgctatc
    36541 aggtcgggaa caaagcccac atcctgcgga cgcacgcggt cgccgggctg gatctgccag
    36601 gagaagaccg cgcggatatt ctctttggcg atgtccggat tgaaatgcgc catcgcaaac
    36661 gcctgcttcc aggtatccca cggccaggtc tgattgccgg agaaccagcg cccagtcacc
    36721 gacggcgtga cggtgttata tttcaccgca ccgcccggtg agcgccagtt accgttgagc
    36781 gtttcgatcg ctttcaccgc gacgcgcgtc tgttccggcg tcgcatccgg attggttaac
    36841 cctttcttca gatactcttc ccagcgttgc tgcgaggcgg tgagataaaa cgccggacgc
    36901 gccagaatat cgcggatctg catttgctct ttgctaactt cctgagcggt cagcagatgg
    36961 gaataggtgg tgtagagcgt cgtcgaaccg ttgatatgcg ccttactggt aaagcgatta
    37021 ccgttgattt cagtctgcac cggcagggat ttatgcacct gatattctga ttcaccggag
    37081 gtcagcagat cccaggtggc gcgcactttg ccaaaggtga ctttcaggcc atcacgggtg
    37141 gcgctgattt tgcgctgata gtcagggtac tcgccagcaa tggttttatc ggaaagcggt
    37201 ttcccttctt tcgcttccag tttttccagc agttcaccgt cccacaccag atccagcggt
    37261 ttattgctgg tgattttggt ttccagtagt gacgtgcgcg gcgtggcgaa gcgaagagtc
    37321 atttcgacct gcacatcttt tgctgtcagt ttttgcacca gcgcgccggg aatactgtat
    37381 gcctccagcg tgaagtcgac tttcttgccg tcctgccaga cggtcaggcg gtcgaaattg
    37441 ctggccataa agttgatgta ttcttccgtc agcagcgcaa cgcctggaaa accgcccatg
    37501 gtattcgggc cgtctggcaa cagatgacca tgccaggctc cgagatcgaa aaacggatta
    37561 aaacgctggt gatcgtcgta atcgtaatcc ttcatgtact gcggcgcgcc agtacggtta
    37621 atcacgtttt tataattgtc ggcgtcagcg gcatgggcgg aaaaacttat cagcagagcg
    37681 caggttactg gcgttaaaat agtttttatt ttcatgagat tacagtcctt attaccagta
    37741 aaaatattgc atcaggaaga tttggtcgct gggatcgtga gaggcatttt tcatgtagaa
    37801 gcggctatca aaagccgttg cgaaacgtcc gccgccgtat tcgtaccaga taccaaactg
    37861 catgaaagag gtggtttcat cgtcagcgtg gtcagggcga tgtttggcgt aggtgtaagc
    37921 ggtggagaga taaacgccct ttaacgcttc atacatggcg ctcaccatca tcccgctttc
    37981 acttcccggt acgtccagcc cgtcggcgcg tccagtatgg tgccaggcgc gagcggcaaa
    38041 gttaggagta agcaggcccg tgagatagag ctgtcctgtg ccgtcggtga tttccagacc
    38101 gttcatccag gtgatgcctt cggcaaggtc atactggatg taaccgttca tcattgccgg
    38161 ataggtgtat ttgtcgtcgt agcgatcgta cttgccaaaa tgtagccagg ctttgctttc
    38221 gtcatgatgt ccggcaggtg tggcggtaac gctataacga aagttgccgc ttaagttctg
    38281 caccttcagc gcggtcataa tgtcgcgggt attgggaatg acgtagccca gatcgggggt
    38341 gaaatcgccc caccattgca ggtcatccag tgaggaatcc tgacgcagac tgagcatgat
    38401 ttcggtgcca tcattggtac gataaccgcc atagaaacgg ttaattccgc cctcgaaacc
    38461 accccagcta tggtctggca cccaggcatt gccgtcgtgg tcggcctgca cggtccagcc
    38521 ttcgccgtaa atcaggccga accaggatcc gtacttcatc tccaggccac cttcaatata
    38581 ggtgccgtcg ctgtatttat gtttattctc accctctaaa tccatatatc caccaacccc
    38641 taattcgccg taaaaacgaa atgaaggaga agacatcgag gtaatggcgg gcgtttttgt
    38701 gtcgtcatgt tctgccggac gtacttcttc tcctgccgca gaaaaggcgt agcaaaacgg
    38761 cagagcaagt aatgctctgc atggtgcagt gattaatttc attgtgttaa tccatgagct
    38821 aaagaaaaaa tacagccttt tatcgttgta attataaaaa tataaaggca gaaactattt
    38881 tccctctcct catccaggaa gagggaaaat gcctgctcat tttttattag tctgcttaat
    38941 caacattgct ggctggcgtc gcttcaatat ggcgctcttc agccgttaat ccctttatat
    39001 atttactgta tttccaccac gcaaagccga ggaagataac aataccgccg acgttataaa
    39061 aaatgatggt cagaatattc gcgccagtcg ggaatgtcga agcgacaaac cctacggcaa
    39121 atatcgcaat cagcattgaa acaacgataa taccggtgcg gcgggagccc atacggaaat
    39181 cgcgtggcag gtgatctaat ttggcgcgta aattcaggta agccagcatg atgaataacg
    39241 gcggaagcat ggacgctgcg gcggtcatat taataatggt attcatcaga tcctgcacgg
    39301 tattggaacc gagcatcggg ataatcatca gcgggatgac gatcaggaac tggatccacg
    39361 ctgcgcgcgc cggaacgccg ttttcgttca gttcgacggt tttcttacca aagatgcctt
    39421 ccgggatttc ggagaagaaa attttcaccg gcgttgcggt ccacatcagc agggaaccga
    39481 acatcgcggt aaaggacacc agaccgacaa agcgattcat caacgcttcc ggcagaccaa
    39541 aatacgccgc cataccgtgg aatacctgca ccgatccgcc agtaaatttc aactctttgc
    39601 tgctgacgaa gacgttaatc agcaccgagg agacggaata cagtacgccg ataaaaatcc
    39661 cggcgaggat gatcacttta acgaacgatt tcgaaccgcc tttgacgtcg ttaacgtaca
    39721 cagcgacgga ctccgcgcca cctgcggcca taaagatcca ggtggtcacg ccgaggaacg
    39781 cccagttgaa gttcgggatc atcgcgtcaa cggtgatcgg atcggcaggc tgtacgccgc
    39841 caaccagcgc cgtgcctgcc agtaaaatgt aggagagcgt taacagcagc atcagcgttg
    39901 aagtgacgga ggtgattggc cccagcattt tcgccccgtt ggtggaaacc catgtggaga
    39961 aggcgaacag caccatactg ataatggtgg tagcaaccgg tgtcataata tattcgtagc
    40021 cgaggaaggc atacgaagca taagcaataa cgcgcggcaa cagcgaggtg aaaaagaaca
    40081 ggtttacgaa ccaataggta taggcagtaa taaatgccca acgtccgccc agcgaacttt
    40141 ttacccacgc gtagacacca gcttctgagt ttttatttaa cgaaacaaat tctgcgatga
    40201 tcagacagaa gggaataaaa taaaaaatcg tcgcgaggaa aaacatcggt gccgaggcca
    40261 gtccaagctc aatattatta ttgataacgt tgttaaagct gtaaactgcg gcaaaagtca
    40321 gcgagagtaa gccgaatttg ccgattgtat tacgtttggt atcagacata acacatctcc
    40381 gaaaatgtgt agggtagcgg tggcggcaaa ctccttttgc cgccgtagtt gttatttgtt
    40441 atggaaataa ccatcttcga tggtgacttt gagaaccact tttttgaccg cgttattgca
    40501 gataaaccga tacgcttcat ggatatcgca aataacgatt tgcccttcgt ggacctcaac
    40561 ggtttctccg cagcctttta aatattcacg gtcagtttca tcacgataat attccactac
    40621 ctgtaatgtc tctttcggcg catattcaat tttttgctgc ccttgcaggt agtaatgcac
    40681 ttcaaaatag cgtcgatgtc cggtaaatag cgcatcggtc gcggagtcat tttccacacg
    40741 gtaggtcaat gaatcaccga tggagtgggc gacgctaggc tgaatgttgt cgatattttc
    40801 aatcgcttca acgcagcgtt gccacttctt gccagaggcg taaatctggc ggaactgttc
    40861 taagttatcg atgatcctca ttgcttattc tcgctgtgca aattcgtgga aaagaaccct
    40921 gcgccgaact catacgacgc caggctttgc gcggtagctt ctccgccaga aaccggcagc
    40981 aacgtaaagc cgtagctgaa gtcacggaac cagacgcgcc aggagtccag cacctcgctg
    41041 ccccaggagt tggagccgag gccaagcagc tggtggtcga gattcagggt gatgtcatca
    41101 ctgcgctgca actcgttaca gtgctgggca gcgtggatgt tttcctgggt gtagtgccag
    41161 gcactgaagt taattgggcg ctgcggaacc accagcagac cgttgccgtg gcggttagtc
    41221 agtgccgtcc agcggacatg ctgacggttg ccgttgttct gcgggaaggg atagttctcg
    41281 aacatggcat cgacggtgct gcgccagata tcgatgatgt tagcctgctg gctgtcggcg
    41341 tagttttcgc ccggtccacg accgtaatac gccacctgat cgtattcgcc gttaatcccc
    41401 atagtgaaac cgatgcacgg aatgatgtgc ggatagtcgc cgtaacgctc gccggaaagc
    41461 gccacgttaa cctggccatc ggcagcgatg cgccagatgt aggtgcagcg catcccgaaa
    41521 tcaaacaccg gcggggcaat aaccgtgcgg ctgatgatca acacttcacc atcgctctgt
    41581 tctacggcaa agtcgcgcag atgttcctgc atgatctgca aatgattcgg ttgccacagc
    41641 ccttcgtact cctgcttgtg gttgtcgatc atcggcttga agaagttgat ctttggctcg
    41701 cgggtcagca gcgactcgcc atttacctgc caggatgtcg gtttgccact catttttgag
    41761 aaggtgatcg cgaagttgta gccgcgaacg gtgcagctca aacgatcgtc ttccagcgtc
    41821 agcggacgcg cattatttgg tgcgaaaggc actggctgcg cggtgttttc cttcagcggg
    41881 aactgataag tggcgataga atgcccggct tcgctgtagc gggtgcggga atctttggtc
    41941 accgtaatgt tgaggaacgc ttcgcgggcg tccagctgcg gcagcgtgat ctgtaagggg
    42001 gcttcgctat tcggcgcaac gtcgcgcagt ttaatctgct gcgtcgcgag cgtttcacct
    42061 tcggcgcgca cctctgcgtg cagggtgtag tcatcaagcg tggtaaacca cagtttattt
    42121 tcgactttca gctcgccgcg agtcagatcc agcgcgtgga tttttactgg cgcgataacc
    42181 tgtttgtact ctttcaggcc cggtcccggc gtctgatcgg aatagatcaa accatcaaga
    42241 cagaagttat agttgttggg atagtcgccg tagtcgccgc cgaatttata ccagacattg
    42301 ccgttgtcat cctgcgcctg gatcccgtgg tcgcaccatt cccagacata atgtccctga
    42361 atgcaatcgt gcttatagaa gacgttctgg tactccgtca gcccgcccgg tccgttcccc
    42421 atcgcatgag catattcaca gatgatgcgc ggcttcggat gcgggtattc accaaactca
    42481 ttcatcagcg gcacgcgggt gtacatggtg gaaataatat cgaccacttc agcatcgcga
    42541 tcttcttcgt aatgcaccag tcgcgtgtca tccagcgcct tcgccgcatg gtacatcgcg
    42601 cggatgttac agccatagcc ggattcattg cccagcgacc agatgatgat cgaaggatgg
    42661 tttttctgcg cgtgaatatg gcgaacaatg cgctcgacgt agactttttc ccactgcgga
    42721 tcgtcggtaa tacggctgat atcgccgacg ttagcaaagc cgtgcgattc gacgtcggtt
    42781 tccgccatca caaacaggcc gtagatatca cacagttcgt aaaaacgcgg atcgttcggg
    42841 tagtgagcgg tacgcacgga gttgatgttg tgctgcttca tcaactggag atctttctcg
    42901 acgcgatcca ttccaacggc gcggcctttg cgatgatcgt tgtcgtgacg gttgacgccg
    42961 tgcagcatca cataacggtt attgatccag aacagaccgt cgcgcacttt gatatcacgg
    43021 aagccaacgc gttgtggcac cacttccaga acgttgccgt cggcgtcttt cagcgtcatg
    43081 accaaatggt aaagataagg ggattctgct gaccattgct gcggctgttc gacagtaaaa
    43141 gcaaagctgg cgctggtcag tttttcaatt gccaaatgat caatggcgct actgtgcacc
    43201 acgcgttcgc catcaaacag ggtatattcc agcgttgtga cgacagggga ggcggcgaga
    43261 ttttccagca ccacttcgca ggaaagcgtg gcatcgcaat aggcttcgtc aaagtcggta
    43321 cgaacggtga aatcgttaat atgcgtgagt tgttttccga ccagataaac atcgcggaaa
    43381 atccccgccg accaccacat atcctggtct tccacgtagg tggaatccgc ccactgcatc
    43441 acgcgcacac acaacaggtt gtcgccagtt ttaaccatcg cgctgatgtc aaactctgcg
    43501 gtcaggcgac tgcccttgct gaaccccaca tactgaccgt taacgtagac ttcaaaatag
    43561 gtttcgacgc cgtcaaattt gatcagcgtc tgtttaccct gccagccgtc gctgagggtg
    43621 aaaatacgtt gataggcacc ggttgggtta tcgctgggga caaacggcac atcgatgggg
    43681 aacggaaaac cttcgtcggt atattgcagt ttgccgtgac cttccatttg ccacatggcg
    43741 gggacggtaa tatgccccca gtcagccatt aactcagagg tgaaggcttc tggcacttgc
    43801 agcggatggt caaaaaagtg gaaattccac tgaccgctta agggcagaaa caggctgctg
    43861 gtttcacggg caaaggtacg cgcttgcgca acagaatcat atgaaaaaaa gtacgcacgc
    43921 ggcgcaagtc ggtttgcgtg ggtgagctga atgttttccc agcgattcat agggcctccc
    43981 ggtagagaga aatcggaacc attcatggtg atggtagttt gtgtaattgc tggggagttt
    44041 agtaaaattt ttactaaaaa gtagcaggta aatgcattta ctttaactgg atcacgaaaa
    44101 taaacggcag cactgtccgg caaaaacgat tgccggacag tgtgtaaggg gatttaacgg
    44161 gtcgtgccgc gcagttttaa tttgctggga acgaagacta acagcggcag cgcgcgacca
    44221 tcgcgggctt tttcatacac caggttaacg ccctggcttc ccatcatttc ggaatggatg
    44281 cgcacggtgg agagcggcgg aaaggtaaat cgcgcggtgg ggatatcatt aacgctgata
    44341 agcgaaatat cctgtgggat gttcaggcca cgttcatgaa tcgcccgcag tacgccgata
    44401 gcaatggaat cggaagcaac aaacagtgcc ttcggatagt cttcccgcgc caacatttgt
    44461 tttgccagtt catagcccga cgaactggaa aagcctccgc gccagatatc ctcttcgcgt
    44521 accacttgtt tcagtcggcc atattccgca aaggcgacct cacgaatatc cgccttgcca
    44581 ggctcatctt caccgccaat aaaaccaatg cgattaacgc cctggttgat atagaagtcg
    44641 atgatttctt tactgatgcg tgccagatcg atatccaccg catcgtaacc gctgccgggt
    44701 tcgtgaaagt cgataaaaca gatattgtcg gtcaacgcac aggcggcggc gcgcagggcg
    44761 ggcgtgggtt tgccgacaat taaaataccg gtgacgtttt taatgtctgg taatccgctg
    44821 tgttcataac agttggtcag ttcgatcgcc agcttttcgc actgagtttc aatgccgtgg
    44881 cggatcgcca gatagtaagg atcgttgatc tccagctcct gttggtagct gtagatagcc
    44941 agaatatggt gttggttgac tgcacctgtc tggagtttac gggcactact ggtcttgtac
    45001 tccagctttt cggcgatctc gagaatgcga tgtttcgtct cttctttcac attcaatgtt
    45061 ggatcgtcat ttaagaccct ggatactgtc gccagggata cgccagcttc gattgcgatg
    45121 tcttttagtg ttgccatgtt tacctttttt actttccctg atgtgcgccc ccattgtaga
    45181 ggaagtgctt atcgggtcac ctgttttcag taaataaagc gcgtttcttt gacgctgtaa
    45241 cggtaacaca gcggctcacg aatgtgatca cgcctgcatt ctccattttt agcctacagg
    45301 attgagaaaa acttttgcta tagtttagta aaattttacc cgaagggagg aaacaatgga
    45361 aaccgtggct tacgctgatt ttgcacgtct ggaaatgcgc gtcggaaaga ttgtggaagt
    45421 gaaacgccat gaaaacgccg acaagctgta catcgtacag gttgatgtgg gggaaaaaac
    45481 actgcaaacc gtgactagcc tggtgccgta ctacagcgaa gaagagctga tggggaaaac
    45541 ggtggtggtc ttatgcaatc tgcaaaaagc gaaaatgcgt ggtgaaacgt cggaatgcat
    45601 gctgttgtgt gcggaaaccg atgacggcag tgaaagcgtg ttgttaacgc cggagcggat
    45661 gatgcctgcg ggcgttcgta tcgtataaaa caatcggatg gcgacgtcga atcgccatcc
    45721 gatttgatat tacgcttctt cgacacttac tcgcatggcc gccagcgcct tacgcgccgc
    45781 tttgatcacc agttcacact gttcaatggt cagtgtcagt ggcggttcaa tgcggatcgt
    45841 tttggcgtta ttgagcgttc cggccaccag aacgcgctgg cggaacatct cgctggcaaa
    45901 gttatagccg atttcgttat caacaaactc aatcgccatt aacatccctt taccacgcgc
    45961 ttcctgtacc agatcgggat attcccgcgc cagttgacgg aaaccgtcca gcaacatatc
    46021 gcctttttgt tcagcctgag ccggtaagtt ttgttccagc aacacattga tggtcgccag
    46081 cgccgccgca caggccagcg ggttgccgcc aaaggtggtg gtatgcagga acgggttgtc
    46141 gaacaggact gagaacacct cttcagtagc gatggttgcg ccaatcggca tcacgccgcc
    46201 gccgagggct tttgccaggc acaggatgtc cggctgtacg ttctcatgtt cgcaggcgaa
    46261 catcttgccc gtgcgcccca taccggtttg tacttcatcg aggatcatca gtgcgccgaa
    46321 ctcatcgcac agcttacgca cggcggtgag atagcccggc ggcggcagaa ttacgccacc
    46381 ttcaccctga atcggttcga ggatcactgc agccacatca tcaccggttt ttttgcactc
    46441 gctaagggcc gtgcgcatgg cttcgatatt gccaaacggt acatgacgga accctggcag
    46501 cagcggcata aatggtttgc ggaaggtcga tttcgccgtg gccgacagcg cgccaagtga
    46561 tttaccgtgg aacgcgccgc tggtggcaat aaaagtaaac ttgccgcgcg gtgactgata
    46621 agccttcgcc agcttcagcg ctgcttcaac ggactcggtg ccgctattac agaagaagct
    46681 gtatttcagt ttaccgggcg ttagcgccgc aagggttttc gccagcatcg cccgtaacgg
    46741 atcgagcagc tcctggctgt gcagcggttg tttcgcaagt tgattctgta cggcggaaac
    46801 cacaactgga ttacggtgcc ccacgttgaa aattccaaaa cctccaaggc agtcgataaa
    46861 ctcctgtccc tgggtgtcga caagcgtatt taaacctccc gcttgccact ctacggctcc
    46921 gtaatccccg ccggcggtaa cagatttgcg atactctaaa aaccccggat tgacatgctc
    46981 tttgaagtat tcaatcacct cccggttaag tgctttcatc tcctcatgat ctagtgttcg
    47041 cttctcaatg agattcaggg cgtgggcgct gcacgctaaa gccgatgcgc tcgaaggtaa
    47101 cctgttcaaa atatgctccg gaggctcgcg tatcacatga taccgattta agtattgcag
    47161 ggattgcgcc actccggctg cgatcgcgaa aatcgggata aacacaaatg tggttatcat
    47221 ttgcgcaata tttaatgcta tttgttaaca tctgttgtta ttttgcacgg tttttgtcgg
    47281 gtatggattt ggcgattgct gcgcaaatgc acactttcag ggcaacaact gcctgatttt
    47341 tgggcaagat aattaacgtt ttcgtatagt aacagagtga aagtatttta aatcaaggga
    47401 ttagatttat gctttaatcg caaattgcga tctaaatcaa attaatcagt taaagataac
    47461 cgcagcgggg ccgacataaa ctctgacaag aagttaacaa ccatataacc tgcacaggac
    47521 gcgaacatgt cttctcatcc gtatgtcacc cagcaaaata ccccgctggc ggacgatacc
    47581 actctgatgt ccactaccga tctgcaaagc tatatcactc atgctaatga cacttttgtg
    47641 caggtgagcg gctatacctt gcaagagtta caaggtcaac cgcacaacat ggtgcgtcac
    47701 ccggatatgc caaaagcggc gtttgcggat atgtggttca ccctgaaaaa aggggagccc
    47761 tggagcggca tcgtgaaaaa tcgccgcaaa aatggcgacc attattgggt gcgggccaat
    47821 gcggtaccga tggtgcgcga gggaaaaatc agtggctata tgtcgattcg cacccgggcg
    47881 acggatgaag agatcgcggc ggtagagccg ctgtacaaag cgttgaacgc cggacgtacc
    47941 agtaagcgta ttcataaagg cctggtggtg cgtaaaggct ggctgggtaa actgccttca
    48001 ttaccgcttc gctggcgggc gcgtggcgtg atgaccctga tgtttatctt gctggcggtc
    48061 atgctttggt ttgttgctgc cccagtggtg acgtatatcc tctgtgcgtt agtggtattg
    48121 ttggcaagcg cctgttttga atggcagatt gtccgcccga tagaaaatgt cgcccgtcag
    48181 gcactgaagg tggcgaccgg agagcgtaat agtgttgagc atctgaatcg cagcgatgag
    48241 ctggggctga cattacgcgc ggtagggcag cttggcctga tgtgccgttg gctaattaac
    48301 gatgtctcaa gccaggtgtc cagtgtcaga aatggcagtg agacgctggc gaaaggcacc
    48361 gatgaactga acgaacatac ccagcagaca gttgataacg ttcagcaaac ggtggcgacc
    48421 atgaaccaaa tggcggcgtc ggtgaaacag aactctgcca cggcgtcggc tgccgataaa
    48481 ctttctatca ctgccagtaa tgcggcagtg cagggcgggg aggcgatgac cacggtgatc
    48541 aagacaatgg acgatatcgc cgacagtacc cagcgcattg gcaccattac ttcgctgatt
    48601 aacgatattg cgtttcagac caatattctg gccctgaatg cggcggtgga agcggcacga
    48661 gccggcgaac aaggcaaagg ttttgcagtg gtggcagggg aagtgcgtca tttagccagc
    48721 cgcagcgcca atgctgccaa cgatattcgc aagctgattg atgccagtgc tgataaggtg
    48781 caatccggtt cgcagcaggt acatgcagcc ggacggacga tggaagatat tgtggcacag
    48841 gtgaaaaacg tcacccaatt gatcgcccag attagccatt caacgctgga acaggccgat
    48901 gggctttcca gcctgacccg tgcagtggat gagcttaacc tcatcaccca gaaaaatgcc
    48961 gagctggtgg aagagagtgc gcaggtgtcg gcgatggtaa aacaccgcgc cagccgactg
    49021 gaagacgcgg tgacggtgct gcattaatcg atatgccgga tccggtgttt gatacacgat
    49081 gcctgatgcg atgctggcgc atcttatcag gcctacgggg tgtgtagggt acgccgcatc
    49141 cggcaatcgg tgattaatcc agttgcgtaa tatcaaaagc ggcgcggtcg atcaccgcaa
    49201 tgatcttttt tatctgcgca tcagtgatat cgctctggtt gacgcgtaaa tccagcaccg
    49261 ctttaaaatt atccagcgcc cgcttcattt gcgggttctg gcggagtgca gcaccaacgc
    49321 aacgcgcttt gatgcgttct tcgatcatct ccacctgttc gcggttttct tccagccact
    49381 gcgcgccctg ttcggtcagt gcaatctgct tcttaccacc ttcctcttcg cggatggtaa
    49441 tcagcgactg ctcctgcaga aaatccagcg ttgggtagat gacgcccggg cttggggtgt
    49501 aattcccctg ggttagattc tcaatcgctt taatcaattc gtaaccgtgg ctgtcatcgc
    49561 gcgagagaat atccagaatc accagacgca attcaccgtg accaaagaaa cgctgccgac
    49621 gaccgccgcc gcgaccgtgg cgaccaccgc agcattgacc gtgttcatgc tggtgaccgt
    49681 gtccgcagtg ctcatgttct gacttctcac ctttgcagca gccttcatgg cgtggctggc
    49741 cttcatgttt acaacaccct tcgtgatgat ggctcatatc agcctccttt tgcttaatta
    49801 gatatatcta atttatatct gatatgagcg cttttgcaag tataaaaatg atttttaaac
    49861 gtgaatacac ctcacatcca ggccggataa ttcgttcacg ccgcatccgg cagccttgct
    49921 acgacgctga atgtcttctc atacttcaga tatatcagtt ctacaaatcg cttgcattta
    49981 tcatgattaa caatcattat catttgcgaa atttatttag atatatctga ttactatcac
    50041 gaaggcgata acaatgaata actccccccg ctacccgcag cgcgttcgca atgatctgcg
    50101 cttccgtgaa ttgactgtgc tacgcgctga gcgtattagc gccggttttc agcgcattgt
    50161 ccttggcggc gaggcgctgg acggttttac atcgcgcggc tttgacgatc acagcaaact
    50221 cttctttcct caatctgatg ctcactttgt gccgccaacg gtaacggaag agggcatcgt
    50281 ctggccggaa ggaccacgcc caccgtcgcg tgactatacg ccgctgtatg acgaactacg
    50341 ccatgaactg gcgattgatt tctttattca cgacggtggc gtcgccagca gctgggcaat
    50401 gcaggcgcaa ccgggcgata aactcacggt ggcaggtccg cgcggttcgc tggtggtgcc
    50461 agaggattac gcgtatcagc tgtatgtctg cgatgaatcc ggaatgcccg cactgcgccg
    50521 ccgcctggaa acgttgagca aacttgctgt taaaccgcaa gttagcgcac tggttagcgt
    50581 gcgggatcac gcctgccagg attatctcgc gcaccttgat ggttttaata tcgaatggct
    50641 ggcgcatgat gagcaggcgg tagatgcgcg tctggcgcag atgcaaatcc ctgccgatga
    50701 ttacttcatc tggataaccg gcgaaggcaa agtcgttaag aatttaagcc gccgctttga
    50761 agcggaacag tatgacccac agcgggtacg tgcagcggct tactggcacg caaagtaact
    50821 gatatataaa aagaaaaagg ctgacgattt ctcgtcagcc tttgctatat ctggtggccc
    50881 ctgctggact tgaaccagcg accaagcgat tatgagtcgc ctgctctaac cactgagcta
    50941 aggggccatg gtagcggatt ataaagtaac tccgtgtcgc aatccagcca ttaccgcgcg
    51001 cctgctgttt ttataaacaa tgtattttca atccgttata cttttcctgg tgatgttaga
    51061 aaggagtaaa tatggttgag gatattttgg ctccagggtt acgggtcgtg ttttgcggta
    51121 tcaaccctgg gctttcatcc gccgggactg gttttccctt tgctcatccg gcaaatcgct
    51181 tctggaaggt gatatatcag gccgggttta ccgaccgtca gttgaagccg caggaggcac
    51241 agcatctgct ggattatcgt tgtggcgtca ccaaactggt agaccgtcca acggtgcaag
    51301 ccaatgaagt ttcaaagcag gagctacacg caggcgggcg taagctgatt gaaaaaattg
    51361 aagattatca gccgcaggcg ttggcgattc tgggcaaaca agcatatgaa cagggattca
    51421 gccagcgcgg tgcacagtgg gggaaacaaa cgctcaccat tggttcgacg cagatttggg
    51481 tgctgccaaa tcccagtggt ttaagtcgcg tttcactgga gaaactggtt gaagcgtatc
    51541 gcgagctgga ccaggcgctg gtagtgcgtg ggcgataaaa aacgccaccg aaaaggtggc
    51601 gtttgtgcag agggcctagt gccgggtgcg gcgtaacgcc tgatccggcc taccgattaa
    51661 tcgtccagga agctacgcag cacttcagaa cggctcgggt gacgcagttt gcgcagcgcc
    51721 ttcgcttcga tctgacggat acgttcgcgg gtaacgtcga actgtttacc cacttcttcc
    51781 agcgtgtggt cggtgttcat atcgataccg aaacgcatac gcagaacttt tgcttcacgc
    51841 gcggtcaggc cagccagcac gtcgtgcgtt gccgcacgca ggctttcggt ggtcgcagaa
    51901 tccagcggca gctcgagggt ggtatcctcg atgaaatccc ccagatgcga atcttcatca
    51961 tcaccgatcg gcgtttccat ggagattggc tctttggcga tcttcagcac tttgcggatc
    52021 ttgtcttccg gcatcagcat acgttcagcc agttcttccg gcgtcggttc acggcccatc
    52081 tcttgcagca tctggcgaga aatacggttg agtttgttga tagtctcaat catatgcacc
    52141 ggaatacgga tggtgcgcgc ctgatccgcg atagaacggg tgatcgcctg acggatccac
    52201 caggttgcgt aggtggagaa cttgtaacca cggcggtatt cgaatttatc aaccgctttc
    52261 atcaggccga tgttaccttc ctgaatcagg tcaaggaact gcaagccacg gttggtgtat
    52321 ttcttggcga tagaaataac cagacgtaag ttcgcttcaa ccatctcttt cttcgcacgg
    52381 cgggcttttg cttcaccgat ggacatacga cggttgatat ctttaacctg ctcgatggtc
    52441 aggccggttt cttcttcaat ctgctgcagt ttctgcaggg cgcgatgcac ttcttcagag
    52501 acatcgtgca gtttttccga ccacggcttg ttcatcgcaa ttgccgcgtt gaaccaggta
    52561 tcgctggttt cgttgccggt aaacagggta atgaagtttt tcttcggcat tttgcactgc
    52621 tcaacacaga gcttcatgat cagacgttct tgcgtacgaa cgcggtccat catgacgcgc
    52681 atgctgttga ccaggtagtc aaactgcttc ggcaccaggc ggaactgttt gaatacttca
    52741 gacagtttca ggatctcttc ctgagcggca gcgtgactgc gacctttcgc tttgatggtg
    52801 tcacgcgtta caacgtactg agcgcgcagt tccgcaaatt tttcacgagc cagttccggg
    52861 tcgatgctgt tgtcatcatc ggcgctgtcg tcatcgccat cttcttcgtc ttcatcttcg
    52921 tcatcgtcca gatcttcctg ggaaagctca gaaccgacgt gagtggcggt aggtgccaga
    52981 tcttcttctg cgttcgggtc aacaaagccg gtgatcagat cggacagacg cgcttcttct
    53041 gcttcaacac gatcgtactg ttccagcaga taggtgatcg cttccggata ttcagcaacg
    53101 gagcattgaa cctggttgat cccgtcttca atacgcttag cgatgtcaat ttcgccttcg
    53161 cgggtcaaca gttcaacggt gcccatttca cgcatgtaca tgcgtaccgg gtcagtcgtg
    53221 cgcccgattt cagattccac gctggaaagc acctgcgcgg cggcttcggc agcatcttcg
    53281 tccgcggtgt tttcagccag catcagatca tcggcatccg gtgcttcttc catcacctga
    53341 atgcccatgt cgttgatcat ttggatgatg tcttcgatct gatctgaatc gacgatatct
    53401 tccggcagat ggtcattgac ctcggcatag gtcagatagc cttgctcctt accacgggtg
    53461 acaagaagtt tcagctgtga ctgcgggttt tgctccataa gacggtatcc acacttattt
    53521 catgaggttg gtgttgggcg attgacccga tgtccttcag ccgttaacgc tgaaatccaa
    53581 cggttgttta ccgccaacga taattacgag ggcgtactta tatatttgcc gctgcctctc
    53641 agtgcggctg tcgggggctt cccgatcgct cttcggcact taagccgtta aatcactttt
    53701 tcgccagctc ctggtttaat gtccagagct ccaggcgttc ttcgttgctt aaaccatgcg
    53761 tgcgctcacg agcgattaac tcttcctggc gcagttcaag cagcgaatca aacatatggt
    53821 tgagtgagtc ggtgaaggtt tgctcagcaa tattcttatc tgctatatcg tcccacatcg
    53881 acagtttttc aagggtggca gcattatttg taccacgata gtgctctaaa agttgcccgg
    53941 tggtcagacc tggctgagag agacaagtgt tgaccagttc tctgaataag ccaagtccag
    54001 ggagcttatt ttcatccaga ttctcaagcg gcgggaccaa cgtcgctaat tctggatttt
    54061 gcaccagcaa ccctataagt atacgcatgg tcgtgcgttt tagctgcgga acagggcgag
    54121 aaacgccgct ctctgccgct tttggcatta atcgttcaag ctggctgtca tcaagtatgc
    54181 ctaatttgtt gcctaattcc tgacgaagat atattcgcag cgtttcgccc ggcacttgcg
    54241 atatcaatgg cagtgccagc gtactcaaac gtgcgcgccc gtcaggggta ctcagatcaa
    54301 cttgcggcat caggctgtta aacagaaatg cggagagcgg catcgcctgc tccatccgcg
    54361 cttcaaacgc ttgtttacct tcttttcgta ccagcgtgtc agggtcttcg ccatcaggca
    54421 aaaacataaa gcgtagctga cgaccgtctg tcatgtaagg cagcgccgtt tccagcgctc
    54481 gccaggcggc atcgcggcct gcacggtcgc cgtcataaca gcaaatgaca ttgttggtcg
    54541 cgcggaacaa cagttgtatg tgatcggcgg tggttgacgt acctaacgac gcaacggcgt
    54601 aattaatgcc gtattgcgcc agcgccacca cgtccatata gccttcgacc acaagcagac
    54661 gattgggttc agcgttatcc tgctgcgctt cataaagacc gtaaagctgg cggcctttat
    54721 ggaaaatgtc cgtttccggc gagttcaggt atttgggggt atcgttgccc agcacgcgtc
    54781 caccaaaacc aatcacccga ccgcgtttat cacgaatggg gaacatcacc cgctcgcgga
    54841 aacggtcgta actgcgcccc tgatcgttag tgaccaacat gcccgcatca atcaatgact
    54901 ggcgattttc tggattgccg ccaaaccgct tcaggacgtt gtcccagccg gggggcgcaa
    54961 aaccaatcgc aaagcgggcg ataacctcgt ggcttaatcc gcgtttttcc agatactggc
    55021 gcgcagacgt ggcaacaggt tgctgtaaag attgttggta aaacgtattc agaccgtcca
    55081 tcaactgata aagcgtttgc ctctgatggc gctcgatctg gctggggccg ctgcctgctt
    55141 caaatggcac ttcaagattg tgcattgctg ccagctcttc gaccgtttcg acgaactcga
    55201 gcttgtcgta gttcatcagg aagtcgatcg cgttgccgtg cgcgccacat ccaaagcagt
    55261 ggtaaaactg tttctcaccg ttaacggtga atgacggggt tttctcgttg tggaatggac
    55321 aacacgcgtg gaaattcttg ccctgctttt tcagcttcac acgggcatcg atcagatcga
    55381 cgatgtcagt gcgtgccagc agatcattaa tgaatacgcg tgggattcgt ccagccatag
    55441 gccccgattt ttagcaattc ataaacgaaa ataagccgcg cattcctttc ggaagcacgg
    55501 ccttacaact acaactcggt ctgatcggag agcaacgctc tcggggaatt agtacagacg
    55561 agtgcggcgt gcgttttcgc gagccagttt cttcgcgtga cgtttcactg cagaagcttt
    55621 agcgcgctta cgttcggtag tcggtttttc atagaactca cgacgacgaa cttccgccag
    55681 aacacctgct ttttcgcagg aacgcttgaa gcgacgcaga gctacgtcga acggctcgtt
    55741 ttcacgtact ttaattaccg gcatgtgcct ctcacctttg attaattcgg tttgccgctg
    55801 gcatcaacgc cagcttattt caaaatggtg cggaatttta ctgcaattgc tgctgctttg
    55861 taaagcaccg cggccttttt tgaaagggac ttttataagg gtgaggagta tacacgaggc
    55921 tttctccagg ggcgaacaaa gttttacatc aacccgcatt ggtcctacac tgcgcggtaa
    55981 taaagcgagg taaaacaagt catgcgtgta ctgggtattg aaacttcctg cgatgaaacc
    56041 ggcatcgcca tttacgacga tgaaaaaggt ttgttagcca accaattgta tagtcaggtg
    56101 aaattgcacg ctgactacgg cggcgtcgtg cctgaactgg cctcccgcga tcacgtgcgt
    56161 aaaaccgtac cgttgatcca ggcggcgcta aaggagtcag gtttaacggc aaaagacatt
    56221 gatgctgtgg cctataccgc aggccctgga ttagtcggcg cgctgctggt tggcgcgacc
    56281 gtggggcgtt ctctggcgtt tgcctgggac gttccggcga tcccggtaca ccatatggaa
    56341 gggcatctgt tagcgccgat gctggaagat aacccaccgg aatttccgtt tgtcgcgctg
    56401 ctggtttccg gcggtcatac gcagttaatc agcgtgactg gcattggtca gtacgagctg
    56461 ctcggcgagt ctatcgatga tgcggctggt gaagcgtttg ataaaaccgc gaagctgctg
    56521 gggctggatt atcctggcgg gccattactg tcgaaaatgg cggctcaggg tactgccggg
    56581 cgctttgtct tcccgcgccc gatgaccgac cgtccggggc tggatttcag cttttctggt
    56641 ctgaaaacct tcgcggcaaa taccattcgt gataacggca ccgacgacca gacgcgtgct
    56701 gatatcgccc gcgcctttga agatgcggtg gtcgatacgt tgatgattaa gtgtaagcga
    56761 gcgctggatc agacgggctt taagcgactg gtaatggcag gtggcgtgag tgctaaccgc
    56821 acgttacggg cgaagctggc tgaaatgatg aaaaaacgcc gtggcgaagt gttctacgcg
    56881 cgtccggaat tttgtactga taacggcgcg atgatcgcct atgccggaat ggtgcggttt
    56941 aaagcaggcg cgacggcgga tcttggcgtt agcgtgcgtc cgcgctggcc gctggcagag
    57001 ttaccggccg cgtaaaacta ttaggtgccg gagagtcact tccggcaccg tcctcactta
    57061 aagcaacacc atgggcatcc acagtaagcc ggtaatcacc agcaacacga ggaatatcag
    57121 cccaaaaatt gcccccagtc gccagtaatc caccgttggc agataaccac taccgtagta
    57181 aatcggactg ggtccggtgg cgtatggcgt aagaatgctc cccagaccaa ttgccgcgcc
    57241 aaccatcagg cagaacacgg gaagcgggat ttccggcatc gccagcgcgg cggcaatcat
    57301 catcggcgcg agagcggagg tatacgccgt ggcgctggca aagaagtagc gcagcagata
    57361 aaagaccaca atcaacgcca ccatcaccat cgttggcgaa taaccgttta agctgcctgc
    57421 taacagtttg ccaaaccagc taataaaacc ggtgttgttg agtccggtag cgagggtgat
    57481 aagcgaggcc agccagaaga aaacgttcca cgccgcttta ttactgacaa tgtcgtccca
    57541 actgataatg cgcagaagca gcatcagcgc caccacgctg taaccgacca tcgcggcatc
    57601 gatataatca ccgccgaaaa tccacagcac cagcgcgcct accatcagcc ccagcatccg
    57661 tttttcacgc gaacagagcg ggcccattgc ctgcagttcc gtctctgccc agcgcggcac
    57721 ctgatcacca gacttcagta ccggcgggta cagcacgtaa gccagccagg gaaccagcag
    57781 aaccagtaaa atactgagcg gcaacatccc gaggaaccag tcgccccaac tcagtgtggc
    57841 gtgagatgcg cttttcatca ggccaattaa cagcaagtta ggtgccatcg ccgtcaggaa
    57901 aatggcgctg gtcacgcagt cggcaacaat ccccatccac atgatgtacg agccaatgct
    57961 gcgcgaactg ctgtcgtttg gttgtgattg atagagcggt ggcaggttac ggatgatggg
    58021 atagataatc cccgcaccgc gcgccgagtt ggacggtgtt acaggtgcca ggatcagctc
    58081 ggagaacatc accgcatagc cgagaaacag cgtacgatgc cccatctttt tcaccagaat
    58141 cagcgcaatg cggcgtccaa gcccggtttt ttcatagcct gtgccaaaca taaaggcggc
    58201 gaaaatcagc cagataaccg aattagaaaa accagaaacc gcccacgaga gggatttggc
    58261 ggtgaactta aaacctggtt gggcgagctg ctccgggcta aacagcagcc acggcgagag
    58321 aatggcgata atggagatac ccaccatcgc caccacggcc cccggcacgg gttcgaggat
    58381 cagtccaacg atcacgccag taaaaacggc aaagtagagc caggtatgac tctccagccc
    58441 tgcgggaacc ggaattagag caataatggc gatgaccgcc agcggcgcaa ggtatcgcca
    58501 ccattcagtg gaaggtttca tcgtgttatg cctgcgaaaa aggagagggg gtgagcctct
    58561 ccgggagggt tatttgatgt agtggacgtg ctcgcaaatc tcttccacga tgggatcgcg
    58621 gcgttcggcg aacagctttt tgttttcggc tatcaggttg ttgccgtggg tatcaataga
    58681 gacaatcagc ggaccgaact ctttgacccg gcagacccac agcgactccg gcatcccgag
    58741 ttctgtccag tgcacttctt caatctcttc cacctgggtt gccgccagta ctgcgcagcc
    58801 tgccgggaaa atcacatgta gcgccttgaa tttctgacag ccttcttcgg tcagcggccc
    58861 cattccgcct ttgccgacca ccagtttcac gccggtctgt tcgataaatt cacgttcaaa
    58921 actttccata cgcatactgg ttgtcgggcc gacggatacc atctcccatt tgtcgccgtt
    58981 tttgcgcacg atggggccag cgtggaaaat cgctttgccg ttgagatcgt aagggatcgg
    59041 acgtttcagt tcgatcaagc ggcggtgaca aacgtcgcgg caggttacca gcgtacctgt
    59101 caggtagatc acatcgccga cgcgaatatc ttgcagatct tcagctttga tcggggttgt
    59161 caggatcttt ttcataacgc gctccgggtg tgagacagat tttcaaaggt gagatcggca
    59221 tgaaccagca gtgtgccgcg acgatgcgcc cagcagcctg tagaaacagc aacgccgatg
    59281 gttgacggat ggcgggcggc agattcgata tgtacgccca tcactgaact gttgccagtc
    59341 agcccttgtg gaccaatccc caaacggttg agtccttctt ccaggcgtag ctccagctct
    59401 gccgctttcg gattggggtg gcggctgcca atcgggcgca aaatggcttt acgcgagagc
    59461 actgcggcgg tttccaccga ggtggcgatg cccacgccta ccagtaccgg tggacaggcg
    59521 tttacggcga gggtggaaat attttcgaag acgaatttca ctacgccttc gtagccttct
    59581 gacggcatta acactttcga gcggccaggt agcgtgcagc cgccgcctgc catgtaaact
    59641 tcgatttccg catcgtcacc gtcggggacg atatcccagg tgacccacgg tacgccgctg
    59701 ccggtatttt tgtcggtgtt cacttcgtca aaaatttcca ccgcgttgtg gcgcagtggc
    59761 gctttgacgg ttgcttcttc cacagcttgc ttaagaatgc tttgcagctc gccaagcagc
    59821 gggaaacggg aaccgacttt aacgaagaac ataatctccc cggtgtcctg acaggcagga
    59881 cgattcaggt cgattgcttt ttgcatgttg tcgaacatcg tgtggtagat gattttcccc
    59941 atcgacgacg tttcggcatc ctttagctgt tttagtttat ccaccacgtc atcgggcatt
    60001 cgggtagaaa tcatggcggt aaagttagcg acaatctccg tcaacttatt cactgcctgt
    60061 tgcttattac tttcgctcat catggcaact ccagtttatg tatttgtctg gaaaaattca
    60121 ccgccacaaa ctaccactaa aaatgtggtt ttatattttt tgccaccgtg aatatgtaat
    60181 tcacagttcg tgaatcaacg cgaaaataag aatgaatatt gcgccagagc agggaatggc
    60241 aatgttttgc gaaatacact gcgcttatca caactgcgga taattaacga tgctgaatag
    60301 ctggccttta gccaaagact tgcaggtact ggtagaaatc gtccacagcg ggagttttag
    60361 tgctgcagcg gcgacgcttg ggcaaacgcc tgcatttgtc accaagcgga tccaaatcct
    60421 tgaaaatacg ctggcaacaa cgctgctgaa ccgctccgct cgcggcgtgg cgctgactga
    60481 aagtggccaa cgttgttacg agcatgcgct ggaaatcctc acccaatatc agcgactggt
    60541 cgatgacgtt acgcaaatca aaacgcgccc ggaggggatg attcgtattg gctgtagttt
    60601 tggttttggg cgcagccata ttgcgccagc cattaccgaa ctgatgcgca attatcctga
    60661 gttacaggtg cattttgaat tgttcgatcg gcaaattgat ttagtgcagg ataatattga
    60721 tctggatatt cgtattaatg acgaaattcc tgattattat attgcgcatc ttttgacaaa
    60781 aaataaacga atattatgtg cagcacctga gtatctgcaa aaatatccgc agccacaatc
    60841 cttacaggaa ttaagtcgtc atgattgtct ggtgaccaaa gagcgtgata tgacccacgg
    60901 aatatgggag ttggggaacg gtcaggagaa aaaatcggtg aaggtaagcg ggcatctttc
    60961 ctccaatagc ggcgagattg tgctgcaatg ggcgctggaa ggaaaaggaa ttatgctgcg
    61021 ttctgagtgg gatgttttac cgtttctgga gagtggcaaa ctggtgcgag tattgccgga
    61081 gtacgcacaa agcgccaata tctgggctgt ttaccgggag ccgctctatc gcagcatgaa
    61141 attacgtgtc tgcgtggaat ttctggcggc atggtgccag caacggctgg gcaagcccga
    61201 cgaaggctat cagattatgt agatccacca gaaatcactc gggatccttt tcgcgctttc
    61261 ttttgaattt cgtccagatt tttgtctcct gacgacgcca cagacgctgg atgttgtcat
    61321 gatgacgcag caggatcagg caagagagca tcgaaaccgg gaaggtgaat tgtggcttaa
    61381 accaccagac ataaaacgga gcaatcagtg cactgacaat cgctcccagc gacgaatatc
    61441 cgctcaatag cacggtcagt aaccaggttc ccgccattac tccggtgaga tcccagccaa
    61501 ttggtgcgat ggcaccaaaa gcggtagcaa cgccttttcc tcctttaaaa ccgaagaaaa
    61561 cgggccagat atgtccaaga caggcggcga tggcaattaa gcctagccag aaggggctga
    61621 cacctaattc atacgcgccc cagacaggca acattccttt cagaacgtcg aaaatcagta
    61681 ctgctacggc tgctcccttg ccaccgatac gtaacacatt ggttgcgcct ggattgccgg
    61741 agccgctggt tcgcggatcg ggcagcccac acaagcggca aaccagaatg gcactggaga
    61801 tggagccgca gaggtacgcg atgaggatca ttccaggcgc gattgcactc ataagctgtt
    61861 ccgttttgaa aattcgtgtt caacgatgaa tctgtggata atacgcacat ttcgccggaa
    61921 gtggtatccg gttagccaaa aagcaggcag gacgtgatgg atattgtatt tatagagcaa
    61981 ctttcggtaa tcaccactat tggtgtttac gactgggaac agaccatcga acagaagtta
    62041 gtgttcgata tcgaaatggc gtgggataac cgtaaagcgg cgaaaagtga tgatgtggcg
    62101 gattgcctca gttacgctga cattgcagaa acggtagtca gccacgtcga gggggcgcgt
    62161 tttgcgctgg tggaacgtgt ggcggaagag gtggcggagc tgctgttagc acgcttcaac
    62221 tcgccgtggg tgcgtatcaa actcagcaag ccaggcgcag tggcgcgggc ggcgaatgtt
    62281 ggcgtcatca ttgagcgtgg caataatctg aaagaaaata attaatttta cagctgttaa
    62341 accaaacggt tataacctgg tcatactgca gtagttcgga caagcgttac atttttataa
    62401 tttaggggtt tattgatgag cgatatgcac tcgctgctga tagcggcaat attgggtgtg
    62461 gtcgaaggat tgacagaatt tctgccggta tccagcacgg gccatatgat tattgtcggt
    62521 cacttgttgg gatttgaggg cgacacggcg aaaacctttg aagtcgtgat ccagttagga
    62581 tcaattctgg cggtagtagt gatgttctgg cggcgtctgt ttggcctgat tggcatccac
    62641 tttggtcgcc cgttgcagca cgaaggagaa agcaaaggcc gtttaacgct gatccacatt
    62701 ttgctgggga tgattccggc ggtggtactg gggctgttgt tccacgacac gattaaatca
    62761 ttgtttaacc cgataaatgt gatgtatgca ctggtcgttg gcggtctgtt gctgattgcc
    62821 gctgaatgcc tgaagccgaa agagccgcgt gcgccgggtc ttgatgatat gacctatcgt
    62881 caggcgttta tgattggctg tttccagtgt ctggcgctgt ggccgggttt ctcccgttcc
    62941 ggggcgacca tttcaggtgg gatgctgatg ggggtgagcc gttacgctgc ttccgagttt
    63001 tcgttcctgc tggcggtgcc gatgatgatg ggcgcaacgg cgctcgatct ctacaaaagc
    63061 tggggcttcc tgacaaccgg cgatatcccg atgtttgccg ttgggtttat caccgctttt
    63121 gtggtggcgc tgatagcgat taaaaccttc ctgcaattga ttaagcgcat ttcgtttatc
    63181 ccgttcgcca tttatcgctt tattgtggcg gctgcggtgt atgtcgtgtt cttttgattg
    63241 aggaatagtg tcggatatga cgcttgtgcg tcttatccga cctggccggt gtttgcaata
    63301 aattgaaatt caagtgctta atcaggcttt ggacaacgtt gttccttcca gctggctacc
    63361 gccgcaatcc gccgtcgggt cagctcctcg cgaatctcca cacctttaaa tcccgcttca
    63421 acgacggctt ttgttggcac tgactgtgcc acttcccagg cttcgcgcaa ccagcggcct
    63481 tgcgggtagt ccgctgattc aaaaccggtt ctgccgcgca cgtcagcctc gctggtcagc
    63541 gccagttgct cgacacgctg cggtttacgc caggcgtcga tggaatcaaa caatttgacg
    63601 atggtttttg ggttcagcat tgggaaggtg tggatgagat cgtgaaactc agccaccagt
    63661 ctggctaaat cgcgaatttc atttggcacg cgcagacgct gacagagttg ttccactaac
    63721 ttaacacccg ccgggccatg accatgatga cgcggccaaa gttctggtgg cgtcagtcct
    63781 ttaccgagat cgtggcataa agttgcgaaa cggacatcga cctgcggact tagcatcgcc
    63841 gccattgaga gcgtcattaa ggtgtgaata ccggtgtcga tttccggatg ccacctggca
    63901 ggggccggaa cgccaaacag ggcgtcaatt tccgggaata aaacgcgtag tgcaccacaa
    63961 tcgcgcagta cctggaagaa cacctgggga ttgcgggtgg tgagggcgct ttccgtctct
    64021 ttccataccc gttcaggcgt caggtgttcc agttcacccg catgggtcat ctcgcgcatc
    64081 agtgccagag tttcatcggc aatacgaaaa ccgaggtggg cataacgcgc agcaaaacgc
    64141 gccacgcgca atacgcgtaa cggatcttcg ccaaaagcgg gggaaacatg gcgcaacaga
    64201 cgattttgca gatcgcccag accgttgtac gggtcgataa tctcgccgtt atcgtcctgg
    64261 gccagcgcat taatggtcag atcgcgacgc ttaagatcat cttccagcgt gacatccggt
    64321 gcggcatagc aggtaaaacc ggtgtaaccg gaaccggatt tccgttcagt acgtgccagc
    64381 gcatactctt catgcgtttg cggatgcaga aaaacaggaa aatcgcggcc tacctgctgg
    64441 tagcccgcgt cgagcatctc ctgtggcgta ctgccgacca ccacccaatc tctgtctttg
    64501 accggtagcc ctaacaatgc atcccgaaca gcaccaccga ccagataaat cttcacgcca
    64561 tcatcccttc gtcaaataca caattcctaa taataagaca gtgcaacgaa gaaggcgatt
    64621 tagttcatcc agcgatcttt gcgtttgcgg cttgggatca ggtgcggcag taccagaccg
    64681 agcagcaagc caagccccag cacgccgccg ccatacataa accattgcat gatgatggtg
    64741 cgctgtttgt catccagctg tacgctggcg gcatcgacct ttttctgcgc gacaatcagc
    64801 tcgtttttca gtttctgatt ttcttctttt aacccgttga tcacgctgtc gctctgcgcc
    64861 actttttgct gcatttctgc ggtgcgctga ttccaggtgt tatcgatatt ggtgagttta
    64921 tcggtcaggg ttttgacctg attttccaga tctggcacac gggagcgcag gcttggctca
    64981 gtgctaagtt gtttcaacgg gatccaggcg gtacggccag agctgtcttt cacctgggca
    65041 taattggtgt tggcgtcagt ttgtaataag gtcacttcct cgccggcatt aaccgtgccc
    65101 acgaggcgat aatgatctcc cggaccgcta cggacccagg tattcagttc gtcggaaaca
    65161 tagcgcgttt cttcagcgtg tgagacggca gtggcgctaa gtgcgagtaa agttaatccg
    65221 atcaggcgta attttggcat caggctgtcg ttattgtcat ggaaagtgga acgatagtag
    65281 tggcatcagt gtcgctacgc aaagcattcg acatcaatcg gaatcctctg tgtcaggtct
    65341 tgccactgct tcaaactttt acgcccgtca aattgcccgt tgcatggcaa tttggcgcaa
    65401 aatactatct actgacaaaa aagatcgcat taagttcgcc gttcatcgtc acttatgtga
    65461 cataaccgat aagtaaaggc catggctcag gaaatcgaat taaagtttat tgttaatcac
    65521 agtgccgttg aggcgttgcg tgaccatctc aatacgctgg gcggcgagca ccatgacccc
    65581 gtgcagttgt tgaatattta ctacgaaacg ccggataact ggctgcgtgg gcacgacatg
    65641 ggcttgcgta ttcgtggcga aaacggtcgc tatgagatga ccatgaaagt tgcaggaaga
    65701 gtgacaggcg gcttacacca gcgcccggaa tataacgtgg cgttgagcga accgacgctc
    65761 gacctggcgc agttaccgac ggaagtctgg ccgaacggcg aattgcctac cgatctcgct
    65821 tcccgcgtgc agccgctgtt cagcaccgat ttttatcgcg aaaagtggct ggtagaggtc
    65881 gatggtagcc aaattgaaat cgctctcgac cagggggaag tgaaagcggg ggaatttgct
    65941 gagcctatct gcgagctgga actggaactg cttagcggcg acacgcgcgc ggtgctgaaa
    66001 ctggcgaacc aactggtatc gcaaaccgga ttacgccagg gcagcctgag caaagcggcg
    66061 cgtggctatc atctggcgca gggcaatccg gcgcgtgaaa tcaaaccgac caccattttg
    66121 catgttgcgg caaaagccga tgtggaacag gggctggaag cggcgctcga gctggcgtta
    66181 gcgcaatggc agtatcatga agaactgtgg gtacgcggca acgatgcggc gaaagaacag
    66241 gtgctggcag ccattagcct ggtccgtcat acgctgatgc tgttcggtgg tattgtgccg
    66301 cgtaaagcga gcactcactt acgtgatctg ctgactcaat gcgaggcgac cattgcttct
    66361 gcggtgtctg ccgtgacggc ggtctactct accgaaacgg caatggcgaa gctggcgttg
    66421 accgaatggc tggtaagcaa agcctggcag ccgtttttag atgccaaagc gcagagcaaa
    66481 atcagcgatt ccttcaaacg ctttgccgat atccatcttt cccgccatgc cgctgaactg
    66541 aagagcgttt tctgccagcc gttgggcgat cgctaccgtg accagttgcc acgcctgacg
    66601 cgtgatattg actcaatcct gttgctggcg ggttactacg atcctgtcgt cgcgcaagcc
    66661 tggctggaga actggcaggg gctgcgtcac gctattgcta ccgggcaacg catcgaaatt
    66721 gaacatttcc gtaatgaggc aaacaatcag gaaccgttct ggttgcacag cggaaaacgt
    66781 taatcaggca aggataaaat cgcttatgaa gccgctctct tcaccgttac agcagtactg
    66841 gcagaccgtt gttgagcggc tgccagagcc tttagccgag gaatcactta gcgcacaggc
    66901 gaagtcagta cttactttta gtgattttgt gcaggacagc gtgattgcgc atccagagtg
    66961 gctgacggaa ctggaaagcc aaccgccgca ggccgacgaa tggcagcatt acgcggcatg
    67021 gttgcaggag gcgctctgta atgtgagtga cgaagccggg ttaatgcgcg agctgcggct
    67081 attccggcgg cgcattatgg tgcgcatcgc ctgggcgcaa acgctggcac tggttactga
    67141 agagagcata ttgcagcagc tcagctatct ggcggagacg ctgattgttg cggcgcgtga
    67201 ctggctgtat gacgcctgct gccgcgagtg gggaacgccg tgcaatgcgc agggcgaagc
    67261 gcaaccgctg ctgattttag gcatgggtaa gctgggcggt ggggagctga atttctcctc
    67321 tgatatcgat ctgatttttg cctggccgga acatggttgt acgcagggtg gacgccggga
    67381 actggataac gcgcagtttt ttacccgcat ggggcagcgg ctgattaaag tgctggatca
    67441 accaacgcag gatggcttcg tctatcgcgt ggatatgcgg ctgcgtccgt ttggcgaaag
    67501 tggcccgctg gtgctgagct ttgccgcgtt ggaagattat taccaggagc aggggcgcga
    67561 ctgggagcgt tacgcgatgg tcaaggcgcg gattatgggc gatagcgaag gcgtctatgc
    67621 taacgagttg cgtgcgatgc tgcgcccgtt tgttttccgt cgttacatcg atttcagcgt
    67681 gattcagtcg ctgcgcaaca tgaaagggat gattgcccgt gaagtgcgtc gacgtggttt
    67741 gaccgacaat atcaaactcg gcgcaggcgg cattcgcgaa attgaattta tcgttcaggt
    67801 gttccagctc attcgcggcg gacgcgaacc gtcgctgcaa tcgcgctctt tactgccaac
    67861 gctcagcgcc attgccgagc tgcatctgct ttctgaaaac gatgctgaac aattgcgagt
    67921 ggcgtatctg ttcctgcggc gtctggaaaa cctgctgcaa agcattaacg acgaacaaac
    67981 ccagacgctt ccttctgatg agcttaatcg tgcgcggctg gcgtgggcga tggactttgc
    68041 tgactggccg caactgaccg gggcgctgac cgcacatatg accaatgtgc gccgggtgtt
    68101 taatgaattg attggcgacg atgaaagtga aactcaggaa gagtcgctgt cggaacagtg
    68161 gcgtgagctg tggcaggatg cgttgcagga agatgacact acgccagtgc tggcgcatct
    68221 tagcgaggat gatcgcaaac aggtgctaac gctgattgcc gatttccgca aagagctgga
    68281 taagcgcacc atcgggccgc gaggacgtca ggtgctcgac catctgatgc cgcatctgct
    68341 aagtgatgtc tgtgcgcgtg aagacgctgc cgttacgctg tcgcgcatta ccgccttgct
    68401 ggtggggatt gttacccgca ccacctattt agaattgctc agtgaattcc ccgcggcgct
    68461 taaacatttg atttctctgt gtgccgcgtc gccgatgatt gccagccagc tggcgcgtta
    68521 tccattattg ctggatgaat tgctcgatcc aaacaccctt taccagccga cggcgaccga
    68581 tgcctaccgc gatgagttgc gccagtattt gctgcgcgtg ccggaagatg acgaagagca
    68641 acagcttgag gcgctgcgtc agttcaaaca ggcgcagctg ttacgcatcg ccgcagcgga
    68701 tatcgccggt acgctaccgg tgatgaaagt gagcgatcac ttaacctggc tggcggaagc
    68761 catgatagat gccgtcgttc agcaggcgtg ggttcaaatg gttgcccgct acggtaagcc
    68821 gaatcacctg aacgaacgcg aagggcgtgg ttttgcggtg gtcggctacg gcaagctggg
    68881 cggctgggag ttaggctaca gttccgatct tgaccttatc ttcctccatg attgcccaat
    68941 ggatgcgatg actgacggtg agcgggaaat cgacgggcgg cagttttatc tgcgtctggc
    69001 gcaacgcatt atgcatctgt tcagtacgcg tacctcttcc ggcattttgt atgaagtgga
    69061 tgctcgactg cgtccgtccg gggcggcggg aatgctggtg acatccgcag aagcatttgc
    69121 cgattatcag aaaaacgagg cctggacgtg ggaacatcag gcgctggtgc gtgcgcgtgt
    69181 agtgtacggc gatccgcagc tcaccgcgca ctttgacgca gtgcgtcgcg agattatgac
    69241 gctgccgcgt gaaggtaaaa ctctgcaaac ggaagtgcgg gaaatgcgcg agaaaatgcg
    69301 cgctcatctc ggcaataaac atcgcgatcg ctttgatatc aaagctgatg aagggggaat
    69361 taccgatatc gaatttatta cccaatatct ggtgttgcgc tacgctcatg aaaaaccgaa
    69421 gttaacgcgc tggtcagaca acgtgcgtat tctggaacta ctggcgcaaa acgacattat
    69481 ggaagagcag gaagcgatgg cgctgacccg tgcttacact acgcttcgcg atgaacttca
    69541 tcatctggca ttacaggaat tgccgggcca tgtgtcggag gattgcttca ccgcagagcg
    69601 tgaactggtg cgggcaagct ggcagaagtg gctggtggaa gaatgaagta tggtattatc
    69661 gcgcgcaaat tttgaatctc tcaggagaca ggaatgaaag taacgctgcc agagtttgaa
    69721 cgtgcaggag tgatggtggt tggtgatgtg atgctggatc gttactggta cggccccacc
    69781 agtcgtatct cgccggaagc gccggtgccc gtggttaaag tgaataccat cgaagaacgt
    69841 ccgggcggcg cggctaacgt ggcgatgaat atcgcttctc tcggtgctaa tgcacgcctg
    69901 gtcgggttga cgggcattga cgatgcagcg cgcgcgctga gtaaatctct ggccgacgtc
    69961 aacgtcaaat gcgacttcgt ttctgtaccg acgcatccga ccattaccaa attacgggta
    70021 ctttcccgca accaacagct gatccgtctg gattttgaag aaggtttcga aggtgttgat
    70081 ccgcagccgc tgcacgagcg gattaatcag gcgctgagtt cgattggcgc gctggtgctt
    70141 tctgactacg ccaaaggtgc gctggcaagc gtacagcaga tgatccaact ggcgcgtaaa
    70201 gcgggtgttc cggtgctgat tgatccaaaa ggtaccgatt ttgagcgcta ccgcggcgct
    70261 acgctgttaa cgccgaatct ctcggaattt gaagctgttg tcggtaaatg taagaccgaa
    70321 gaagagattg ttgagcgcgg catgaaactg attgccgatt acgaactctc ggctctgtta
    70381 gtgacccgtt ccgaacaggg tatgtcgctg ctgcaaccgg gtaaagcgcc gctgcatatg
    70441 ccaacccaag cgcaggaagt gtatgacgtt accggtgcgg gcgacacggt gattggcgtc
    70501 ctggcggcaa cgctggcagc gggtaattcg ctggaagaag cctgcttctt tgccaatgcg
    70561 gcggctggcg tggtggtcgg caaactggga acctccacgg tttcgccgat cgagctggaa
    70621 aatgctgtac gtggacgtgc agatacaggc tttggcgtga tgaccgaaga ggaactgaag
    70681 ctggccgtag cggcagcgcg taaacgtggt gaaaaagtgg tgatgaccaa cggtgtcttt
    70741 gacatcctgc acgccgggca cgtctcttat ctggcaaatg cccgcaagct gggtgaccgc
    70801 ttgattgttg ccgtcaacag cgatgcctcc accaaacggc tgaaagggga ttcccgcccg
    70861 gtaaacccac tcgaacagcg tatgattgtg ctgggcgcac tggaagcggt cgactgggta
    70921 gtgtcgtttg aagaggacac gccgcagcgc ttgatcgccg ggatcttgcc agatctgctg
    70981 gtgaaaggcg gcgactataa accagaagag attgccggga gtaaagaagt ctgggccaac
    71041 ggtggcgaag tgttggtgct caactttgaa gacggttgct cgacgaccaa catcatcaag
    71101 aagatccaac aggataaaaa aggctaaccg gaaagcggtt cacagatctc gcttcgtaca
    71161 tggcaggcct attgacgctg ttgttttttc aacctagagt aaaggaacaa gggtaaggga
    71221 ggatttctcc cccctctgat gagttgttag taagtcggga aacttaacag taacaacaca
    71281 accagtatga tgacgagctt catcataacc ctttccttat acaaggcccc ttcttcggga
    71341 ggggctttcc cgtttcagcc ccttgctgcc ccccgattgt tgatgggcgc cggaccccgc
    71401 gcaatgcttt cccagaggca attttgcctt ccccgagcgg tcacgcaaaa cgctgcaacg
    71461 tcctgagcat ttgcaccttt tagcggaacg cagatataaa aaatccccgg ctttttgggc
    71521 cagggatatg tgttaatgaa accttcttga cgctgatttt ttttcaacct aaagtaaagg
    71581 aacaagggtg agggaggatt tctcccccct ctgattggct gttaataagc tgcgaaactt
    71641 acgagtaaca acacaatcag tatgatgacg agcttcatca taaccctttc cttctgtaag
    71701 gcccccttct tcgggagggg ctttcccgtt tcagccccct gctgactccc cgattgttga
    71761 tgagcgccag accccacgca atgctttctc tgatgcagtt ttgccttccc cgagccgtca
    71821 cgcaaaatgc tgcaacaacc tgatcatttg cactttttag cggaacgcag atataaaaaa
    71881 tccccggctt tttgggccag ggattattcc tggaagaggg tttactctgc tttttcttcg
    71941 acgggagttg ttgaggttaa gggtgaagtc aatgccgcca gtgagccgcc tgaaacgcca
    72001 atttcattga gcaaggagtc aatcagcggt gcctgtgtgc ggtaagagag agcggctgat
    72061 aatgcttgtt ccgccaggtt tccgcccccc acattacccg tgtttgcatc acccgcagcg
    72121 ccgccacgat tcagaccatc gacctgaata atcttgatac cgtcgattga cttcatcggc
    72181 tcaacggatt tctctattac cgcaggcagc gcctgcaaca aggccagttt gaatttaagg
    72241 ctggtttgtt catcagaaag tacgttgata gcatcgttca gcgcacgttg tgcttctgct
    72301 tccgccagac cctttttacg tgtagcttcg gctaactcaa cgatagccgc cgcctgcatc
    72361 tctgcggctt ctttttctgc tttcgcccgc acggtcagtt caaccgcttt ggtttctgca
    72421 tcctgcgcgg cagcgattag ggcaacttgt ttagcacgat cggcttcggc agtctggcga
    72481 gtggtttcta cgttttgttg ggcgcttacc gcttctgcaa gtgcgagatt agcacgcgct
    72541 tctgcctggg actgttgttc cgatttggcg gcaatagcga tcgatttcgt ctggttagcg
    72601 atttcggtga cctgctgctg ttcgatctct ttaatgcgaa cttcacgttc agcttcaacc
    72661 tttcttgagc ggacggcctg ttcgcggtcg atttctgttt cctgaatctg tcgttcagcc
    72721 agaattcgtg tctgctctgc ttcacgacga cgttcagctt caaaagccgc aatacgtgca
    72781 ttctgttcgg cagtacgggt tttaacctgc tgctcctgct caagcgtcat aaacgcttct
    72841 tgctgttcaa tctccagctt gcgcgatagc gcatcgcgat ttttttcacg caccgcaact
    72901 tctacatcct gttcaacttc gttacgttcg cggcgacggc gctctgtttc ctgagtcagt
    72961 ttggttaaac cttcggcgtc aaaggcattg ttcggattga aatgttcttt cgaggtctgg
    73021 ttaaagttgg taagtgaaac gctctccagt tccagaccgt ttttcgacag gtcttctgcc
    73081 actgtatttt gcaccccctg cacaaagttc tcgcgggtat cctgtaactc atgcatggtc
    73141 atttgcgcag ctgttgcacg gagggcatcg acaaatttat cttcaaccaa catacgtaag
    73201 tcttcaggcg acagggtgcg ttgccccagc gtctgggcag cggtggcaat cccttctact
    73261 gaaggtttta cccgcacaaa gaaagcgact actacatcga cgcgcatacg atctttcgta
    73321 atcaggctat caatggttga gcggctgact tccagcttca gagtattcat attgatgggg
    73381 attatttcat gaaagatcgg catcacgatt gcgccaccgc tcattaccac tttttgccca
    73441 cctaaaccag tacgaacaaa agcttgctct gccgaagcgc gacgatagag cctggcgaaa
    73501 ataattccaa taataaacag aatgcatacg gcaataattg cggtaaacat ccaggagggc
    73561 acagaattaa caatatcatc cattattaaa tttccttttg attaataaat tacaatattt
    73621 ggggccaggg attattttcc gccaaatatc gcgttgcaga aagtcggcaa ataattaaca
    73681 ctttgtctcc tttagtgaaa atttttcctt cttcaggctc cagtagtaaa taatgtattt
    73741 ggccaaattg atcggtgagt tttccttcgc agggattacc tgaagtggct tgatgaccgg
    73801 taattaacgc catgctacca atatattctt cttctgtaat agctgaacta tggtcgcgtg
    73861 gaatccaggg cgcaactatt ttaccggtat aatgcaccgc aataatcgta aacagtaaac
    73921 tgacaggaac cacgaacagg ttcgacagtg gtgattgcca gaccatgatg caggcatgct
    73981 gcaacaggat gccaataaga ccaaaaaaac cagccagtaa gcagagaacg acgagagctg
    74041 gcaatcttcc aatattgaga taatgaagtg cctggctaat atgacctgtg gttatagaat
    74101 cataatggtc aagatgtgca tcaagagcac cggagagcat gtgaccgcag ataagcgcaa
    74161 aaatttctaa caggccgatc aacagtacaa aggaaatagc gaaaagataa ggggtgttat
    74221 agtcggcgaa taaaatcata tatcactcca atgtccattt agtgacgcaa tatttacttt
    74281 gtaatagttt ccttgcttac atttatctgt gttaataata acacaggtta gagaagttct
    74341 ggaagagaaa gtcttttaat atggtttttt atttttcact aaaaagtgtg atcggggaca
    74401 atatatttac gcacgttatg tttaaaggca ctacactgat tggggaatac tgaaatcaga
    74461 aaaagcatat ggccttaaaa ggtatgcgat aaccggagga tgtgcttatg gatcatagtc
    74521 ttaattcttt aaataatttc gatttcctgg cgcgtagttt tgccagaatg cacgcagaag
    74581 gtcgcccggt cgatattctg gccgttactg gtaacatgga tgaagaacat agaacctggt
    74641 tttgcgcacg ttatgcctgg tattgtcaac agatgatgca ggcaagagag ctggagttag
    74701 agcactgata taacgggcct gatggcccgt tttagtgttt gtattagata ctagttatag
    74761 gtgattttca ggattacgtc tttactaaac ggtccctcaa caaccgtttc tgccgggttc
    74821 gcactcagtt ctgccctgaa tggtgcggtg accgaaggcg cactagacga tgaaaaagaa
    74881 gcaaattgtg agaagcggtt aaattccgtt gctgttccat cgttatgaaa tatcttcaat
    74941 agcagaccat tacctatatc cagatggcta taatcactca aaatatccgt agtgaaaaaa
    75001 ctccctaaaa tattaaactg ctcagtacag gccgcacccg gatctttggt catgactacg
    75061 ctaaacgtct cactcacgct ggtattttta attgttcggg aatttatttt accaaagtcg
    75121 acaacgccat cagctggttc cagatcaaca ttaacaaagc agtcaaggac atgaatgtta
    75181 tttaatccgc gaatcctgaa ggtcagattt ttatctactt ctatagcacc tgctccgctc
    75241 atacctttaa attcaagtgt tatatattcg tcaggtaata caagtttttt atttacttta
    75301 ttggcatttt tagctagctt aatatatagc tgcactcgta ctggaaaagt tactgataat
    75361 tgcggttcag gaccgccact acagactgcg ggctttttgt agccattccc gaaggttccg
    75421 gctcctttta tatcaataca tacaggtgct gcaataggta gtggagatgt agaatcataa
    75481 tcaaccccat tataagttac accgaaagta taagagtttt gattataaaa gtcttgacct
    75541 gatgctaaca acatcattat atttgcccat gcagatgggg attcttctcc tggagatggg
    75601 cctggtagtg cattattaca gaaaacattc ataaaatatt cactgctttg ccagatttta
    75661 tcaccttttt taccatcgct ggggatagag attcttggta cgtaaccaat gacaacggta
    75721 tttccacctt catgttcagc atagcagtcc attgcccatg caggtaatga actaaaaccc
    75781 ataaaaaaag taataacaat taacaagtag cgcatattat tgatctcggt tggctacaga
    75841 aatattacaa atgttattta ctacagggca gtttatttca taaaaactta atccaccaaa
    75901 gtcattgata taacccacct gaaaagttga cggaacattt ttaaactgcg tatttgcata
    75961 gctaaaaggg gttaccatta agctttgcgt ttgtggtaac atcgttaccc catttgttcc
    76021 gatataaccc agcgtaacgt gataaggcat cttattgtta aagcggatcg aaccgtcatt
    76081 tctacgaatg atttcaactt tttcgtaagt cattacccca tcgtcttcta attcaatggc
    76141 ttttggccgc cagaatagtt tcaatgcgtg ctgcatagtg acttgcatca catttttttt
    76201 atctgttttg ggcggtattt ctcgcacgtt aaaatagaag agcgtttctc tgtctttagg
    76261 aagttgagca attttttcct gagttatcat tcttatttga atttgctcac tgggatttaa
    76321 acgcaccatt ggaggaacag tgacaataaa gtcacgcgat ttattgcctt tcgtatcttc
    76381 tatccatgtt tgggccagat agggcaggtt tttactttga ttagtaagtt ttaatgcttc
    76441 gcctttatct gactcattca ttatgatacg ggtacgatcc gggatgatgg caccccaggc
    76501 aatgctgctc atacaggaga gtaatactcc tgctgcaatg atattctttg tatttaagta
    76561 gcgcattagt ttcatcctga attaattttg gctaatacac ggtaaaatag ccgttccggt
    76621 ggttaagttg ctgctattgg gtggttgaat aaaacaagat ttgtcacccc agcgtaaagc
    76681 aagtttgtta tcatcctgaa tgccgttgag gtatacaaag ccgccatcag caaccagtcc
    76741 taattctttg tggctggttt catcttttac gctaatcccc agtggtggat gactaccatc
    76801 tgccaggcga ataaccccta tgatttggta gcccttgcgg gtatcaagtt tggcgtagcc
    76861 aatagcaccc tcggttaagg tggtggtgat aaccgagttt tcgatatcca cattttctgg
    76921 cagatttcgg gtatcaacac ttaatgatgt tgttatgtaa ctgctgactg atggaataac
    76981 tccgatgcca taccgattag ttaccgcgcg tttattgttc aacggaatat cttcagtgcc
    77041 gtctgcgtcg atcataaaac gcgagtcagc actaccgcta tagtcgtgga aagcggcacc
    77101 gtggcgagtc gcagtgaatg aaccattcca actggcattc agagaataat aactgtctcg
    77161 ctgtgatgta ccggagaggt agagtcgacc gttctcggta ttatgctgat aactggcgcg
    77221 tagtgacgct ttcatatctt tgaattcatc attgtcgcct gaagcagaaa cgctccagga
    77281 attatttcga tcggaagagt cataccacga agcagtatgc gaaatctcat tatcctgatt
    77341 tcgttgcata ccatagctca atgttctact agttccccag ggaatcgaaa tatttaggta
    77401 cagttgatcc tggttgtctt cttcccagtt tattcggcta aatgttagag aagtggagac
    77461 gttttttaat ggcccgatat caaaatcgcg gctaagtgat aatgaataat tcacattact
    77521 gctggcgtcc cagtaagtat tacgagccaa acttacgtat gtatttaacc ttaatgattc
    77581 aagatactgg ttaaacgtga caatataact ctctttttca ttctgataat tcgtgtaatg
    77641 gttagtgtca ttgatatatt cattcattgt cacaaagttt ttatcagaga aacggtaacc
    77701 agcgaaagtg agctggctac cggtagattc aaaacgtttt gaatagttag cgcggtagct
    77761 ataacccgtt tctttatcct gattatgcaa ctgagcatca gatcgtgtga catcaaaaga
    77821 taatgaacct aatgagttaa ggttaaaacc aacgccggca gccagagatt gataatcacg
    77881 gtttgttaaa actgaaccac catacaggga tacattgttc agccaccccc atgagaattc
    77941 accagtccag aagaagggtt gttgtaagga atcaccacca acgctggtcg gtttacccat
    78001 agcagtggtg tagcgaatct gccctttacg cgtcagataa ggaatactat tagatgcaac
    78061 ttgccattgc gtaacgcgtc cgtcctcttc ttcaaccttg acgtcaagtt gcccctgtaa
    78121 tgtattgaat aaattggtaa tagcaaatgg gcctggagga acattttctt gataaataat
    78181 acggttgttc tgtgagacag tgacctttgc attcgtttgt gcgacacccg tgatttgcgg
    78241 tgcgtaacca cgtaggtctg gcggtaacat attctcatcg cttttcaacg aaatgccaga
    78301 aaaatggaaa gagtcgaaaa tagaggattc agtatcgtat tgacctatag ttagttttgc
    78361 attcattgct gggattgggc gaaacaaata aatacgcgga aaatccaggt tggtcgcctg
    78421 gcttttgcca ttgttaaatg actgatcgta ctggtaatca gtacgcaggc gccaggcccc
    78481 aagattaacc ccagcctgcc cataggaact tatattttgc gaattatcgc cctgatgtgg
    78541 tgcataatga gaggcatata aattgtagtc aagaaatgcc ccagcaatac catgattcca
    78601 aagttcagga ggcgtccagt ttgcatcttt gtattttaac catgcctgag gtgcagatat
    78661 ggataattgc attttccctt tatcgagata agttgtaatt tgtttttctt tttcgatagg
    78721 gtaacaacca tcgatcaggt tttgctgagt tttttcaata aattcatcag taaatcctaa
    78781 taatgttaat tgctctggtg tcacgcaaac tgcagtttgg ttatcaatta atacccattg
    78841 gaggtcaagg tggattggcg tcctcttatt attaatcaga gtgcttagtg aatatttgcc
    78901 gacgggtaat tggccatcag tttcaaattg ggaaaggtta acgttttcac gatcttcggc
    78961 ttcgattaaa tctttgttga attcaacggc ataagctgac gcacaaccaa tgatgataac
    79021 ggataatgaa caataaatat ttttaatcaa ttcgcttatt gtggttaatt ttaatttttt
    79081 atacatctga tccacttatc attaatccgt taatgatgtg gccgggcgaa cccggccaaa
    79141 tgcgattact cgtaagcaat cttgtagtca gcctgagcgt aaacgttgcc cggggtggca
    79201 tctttgcttg gggattccat acgagctttg aaattcagtt cctgatagct gttggtattg
    79261 ttgaacgtaa ttactaccgg agtacctaaa gttacttcgc cgctctggct gtccagaata
    79321 cgtacgccaa cgccagtggc gccgccgatt tcagtttctt tggtattttt cagaagatca
    79381 gactgacccg tcatggtatt tgctgtagtg aaagtaacct tcgcttttga ataagtagtt
    79441 ccaccctgac tcagcatgca gtcctgcagg tgaatagtga aaggttcagc caaagatttc
    79501 tgatcgcttt tcagtacggt atctgctact tcacccagat ttacagttaa atcttcgtca
    79561 cctggtttaa tagaacatgg agcagagata acttcacctt taaatttaac aataccgtga
    79621 ccttcatcag caaacacgtt attggaaaga atcattgcta cgccagcaac aagaagtgac
    79681 tttttaaaag cggacataat attcctttat ataaagataa gtagaaaaga gaatgattag
    79741 taactgttat ttaaggactg ctaatcattg aaatatgata ttttattttg tgttttttat
    79801 aaaattagtt tatctaaata tcgattaagt aaaacttaaa aaatacattg caattatact
    79861 ttcaattgta ctcattcatt tttgtgatgg ttttctgaat gggattacgc gataaggtaa
    79921 tagaaagcac tataaattag aggattaatt cataatttac agtgcattaa agacgaatgt
    79981 ttacagcgtt ggggggagag tctctggatc tggctgcttt ttgatctcag tactgcgatt
    80041 ttccagttcg ctgattcttt gttcaagcag cgccagtttt tcacgagtcc gtaacaggac
    80101 ttgcgtttgg acgtcgaact cttcacggct tacaaggtcg aggcgcgtca gctgcgcttg
    80161 tagggtttgg cggatttttt tctccacatc ttccccgaac tccctgattc ctttaggcat
    80221 tgattcgtga acctggcgag cgatttgctc aatttttttc gggtcaatca ttgtagtttc
    80281 cctgtactga taggtgttga gtgccattgt agtgcgataa gggtaagtca taaaccagaa
    80341 ttatgtgaag ctatgcgttg ctgccgctaa tcattagcgt tatagtgaat ccgcttattc
    80401 tcagggcggg gcgaaattcc ccaccggcgg taaatcaact cagttgaaag cccgcgagcg
    80461 ctttgggtgc gaactcaaag gacagcagat ccggtgtaat tccggggccg acggttagag
    80521 tccggatggg agagagtaac gattctgtcg ggcatggacc cgctcacgtt attttggcta
    80581 tatgccgcca ctcctaagac tgccctgatt ctggtaacca taattttagt gaggtttttt
    80641 taccatgaat cagacgctac tttcctcttt tggtacgcct ttcgaacgtg ttgaaaatgc
    80701 actggctgcg ctgcgtgaag gacgcggtgt aatggtgctt gatgatgaag accgtgaaaa
    80761 cgaaggtgat atgatcttcc cggcagaaac catgactgtt gagcagatgg cgctgaccat
    80821 tcgccacggt agcggtattg tttgcctgtg cattactgaa gatcgccgta aacaactcga
    80881 tctgccaatg atggtagaaa ataacaccag cgcctatggc accggtttta ccgtgaccat
    80941 tgaagcagct gaaggtgtga ctaccggtgt ttctgccgct gaccgtatta cgaccgttcg
    81001 cgcagcgatt gccgatggcg caaaaccgtc agatctgaat cgtcctggcc acgttttccc
    81061 acttcgcgct caggcaggtg gtgtactgac gcgtggcggt catactgaag caactattga
    81121 tctgatgacg ctggcaggct ttaaaccggc tggtgtactg tgtgagctga ctaatgacga
    81181 tggcacgatg gcgcgtgcac cagagtgtat tgagtttgcc aataaacaca atatggcgct
    81241 cgtgactatt gaagacctgg tggcataccg tcaggcacat gagcgtaaag ccagctgaaa
    81301 accgctgctt aatttactgc cttaatcaag aaaccgaagt tgtagcaggc ttcggttttt
    81361 atttttccct gctatgcaag atgttaattc cgcttctctt tctatgagaa aatttcatta
    81421 atatcaggca ttctttttca ttatgatcaa aatcatataa ttgttccgtt attatgcgac
    81481 catatgaata tatccgaaaa aggatatgtg aaatttatac gctaaatgtt tagtattgtt
    81541 aaatattaag ggtaaaagga tgtttatcgc ctggtactgg attgtattga ttgctctggt
    81601 tgtggtgggt tatttcctgc atttgaaacg ttattgtcgg gcgtttcgcc aggacagaga
    81661 cgcactgctt gaagcgcgga acaaatactt aaacagtacg agagaagaga cagccgaaaa
    81721 ggtagaataa ggctttcgtg aagctggcag aagttgtcca tgcgctggac aacttctgat
    81781 gttgttttta accaattccc gccgtttgta gcagcactaa actgaatccc atcactgaca
    81841 ttccacatag tacgccatag ctggggttat tattagggtc aatctctttg gcgagcggca
    81901 ttaattcatc aaccgagagc gccaccataa ttcctgcaac cgccgccatg attgccgcca
    81961 tgaccaccgg ggaaatcatg ctaccgagga ttaaccacgc cagcacacca ccaagaattt
    82021 ctgctagtcc agaaattccc gcccacagaa tcgcggtgcg tttagacccc gttgccgcat
    82081 aaaccgggcc tgccactgcc agaccttcag ggatattgtg caacgcgacg gccagtgcga
    82141 tgccaaatcc cagctccagg ttgctgctcg ccgtgacaaa ggtggcaatc ccttccggga
    82201 agttatgcag actgatgccg agagtgagca gaatggctgt gcgcttgatc gattttggca
    82261 acggctgcac cgatttttgc attaaatcct gcggatgagc atgtggcaac atgcggtcca
    82321 ggccaaaata gccaagcaga ccgaagataa acattccata acccaacaca ggcgacattc
    82381 cttcagctgc tagtgcggca ggaagcattt ccattaatga gatgagcaac atgatccccg
    82441 ccgcaaaacc tagcgaaaac gccagtaagc ggttcgaggg tttttgcccg agaacgccga
    82501 gaaacgcgcc aataaacgtg gctgcccccg ccagtatggt cagaatgaga ggtactgaca
    82561 tcgacaactc cttataaatc ttcaccttca ggcagatcgt caaaataact gatgatcatc
    82621 atcattgtta tccgggttct tactccgccg aacaagcgta ttgtgaggat atcaaaatga
    82681 cacctttagt taaggatatc atcatgtctt caacacgtat gccagcattg tttttaggtc
    82741 acggtagtcc gatgaacgtg ctggaagata atttgtatac ccgcagctgg cagaagttgg
    82801 ggatgacatt gccacgcccg caagcgattg tggtggtttc ggctcactgg tttacccgtg
    82861 gaacaggagt gaccgcgatg gagacgccgc ccacgattca tgactttggt ggcttcccgc
    82921 aggcgctgta cgatacgcat tatcctgctc cgggttcgcc tgcgctggca cagcgtctgg
    82981 ttgagctgtt agcgccgatc ccggtgacgc tggataaaga agcctggggc tttgaccacg
    83041 gctcgtgggg cgtgctgatt aagatgtatc ctgacgctga tatcccgatg gtgcagttga
    83101 gtatcgacag tagcaaacct gccgcctggc atttcgaaat ggggcgcaaa ctggcagcgc
    83161 tgcgagatga aggaataatg ttggtcgcca gcggtaacgt ggtgcataac ctgcgcacag
    83221 tgaagtggca cggtgatagt tcaccgtatc cgtgggcgac gtcgtttaat gagtatgtga
    83281 aagcgaatct gacgtggcaa gggccagtgg aacaacatcc tctggtgaat tacctcgacc
    83341 atgaaggtgg cacgttatcg aacccaacgc cagagcatta tttgccgttg ttgtatgtgt
    83401 taggtgcgtg ggatgggcag gagccaatta ccattccggt tgagggtata gaaatgggca
    83461 gcctgagtat gctgtcggtg cagataggct aacaattacc ggatggcgag tgccatccgg
    83521 tatcgtggct tattcaacaa aaatatgtgg ataaaaccga gacatatcct gggtgatcaa
    83581 tgcacggtct tcacgaatgc caattccggc gggttgatcg ttcaccagcc agctaccaat
    83641 cagcatatag ctgtcgccga atttcggtaa cgggtggaat tgctgaacaa tcatcccttc
    83701 ttcgccatac ggaccttccg ctgcttcaat ggttttgccg ttctcaatga tcgacacgtt
    83761 tgcgccttca cgggagaaga tcggtttaac cacatatttt tccatttgcg gatgatcatc
    83821 ttccgcaaaa taagcgggca gcaggttcgg gtgattcggg aacatctccc acagtagcgg
    83881 tagaagtgcc ttgttggaga taatgctctt ccacgccggt tccagccagc gtacgcctgc
    83941 atcctccagc ttggttgaga acatctcacg caacataaat tcccacggat acagtttgaa
    84001 caggttggaa attacctgat cctgtaaatc cgtgaactga cctttttcac ctaacccgat
    84061 atcatcgatg tagaggaact cagtagcaat ttcagcttcc gttgcgcagt cctgcaaata
    84121 ctgaatggtt ccgcgatctt ccaccgtgtc gcgacagcag gtgagatgca gcaactggaa
    84181 gccatactgt tcacgcagct caacgaagcg atcgatcagt ttttcttgca gactgttaaa
    84241 ctggtcgctg ccctccggca agttaccggc gttaagctga tcttccagcc agatccactg
    84301 aaagaacgcc gcctcgtata gtgacgttgg cgtatcggcg ttattttcca gaagtttagg
    84361 ttcaccagtg ccatcccacg ccagatcaag acgcgaataa agcgatggct ggtgcgtcag
    84421 ccatgactgg cgcacaaaac tccaggtgtg ttttggaatg cggaatttgg tcatcagctc
    84481 atcgctggcg atcacttttt ccaccacttt caggcacatc tggtgcagtt cggcggtgac
    84541 ttcttccagc ttttcaacct gggcgagggt caacttgtag taagcatctt cacaccagta
    84601 cggctcgccg tacatggtgt gaaaattgaa accgtattcg tgggctttct cacgccagtc
    84661 cgggcgctcg gtaatactga ctctttccat cggtatcagc cacccattga acgagaagag
    84721 gtaccggttg cactacgctg catagtgctt tgtttggcaa cagattcacc aaaaccgcca
    84781 cgggtaacgg tagtggtggt cgccggtttt ggtgccattg ccgtcttcgg tacggtcatg
    84841 gtgcggcctg gctgggctgc gccatagttt ttacccgtcg cgtcggtata tttaccgtaa
    84901 gccggactgg ctgggttttt cgaggagaac agcggctgct gtgcaaatcc cgcgccgccg
    84961 cccatcagac gccccatcat gtaaccggcc atcagcggca tccagaaact cccgctggat
    85021 tgctgggcct gcgcctggtt ttctggtgcc atgccagcct gggctggtgc ctgctggcac
    85081 tgaccttcac caaattcagc aacacagtct tcacgggtgg cgtatttcgg cgcagtacgt
    85141 tcggcttctt tcagcgcatt gttgtacgcg gtggtacatt cggcgctttt gcctgggttt
    85201 gcagctgaac agtcgtcagc attttgatag agagacactg tttcatcact cttttcacag
    85261 ccagccagca taaaaacagt ggcaaccgcg agagcgactg gtgtcagatg gcgtgcgctc
    85321 cagtttttgc ggaacgatgc gtggcgtatg gattttgtcc gtttcatttt tgtcttccgg
    85381 gaccagtggt aaatacccat cagaatagag gatggctggt cgaaattgaa gcgagaaggg
    85441 ggaagaatgc ggcagataac ccgtatcttt acgttgcctt acgttcagac ggggccgaag
    85501 ccccgtcgtc gtcatcagtt acggaaaggg ttatgaccgt tactggtggt agtgcgtgcg
    85561 gatgtttgct gaacgactgg tgccgggcta tcaggcgcat aaccatcagc aatagcattc
    85621 tgttccggcg tttgcggtgc aacgttttcc ggattagtgg aaaccggttt gctcagcgca
    85681 ttgttcagtg ccagcagatc ctgctcgttc aacgtaccca gagctgactt aatattcagc
    85741 tgattaatca ggtagttata acgcgcattc gccagctctt gcttggcgtt gtacaacgtg
    85801 gtggtcgcat ccaacacatc aacaatggta cgcgtaccga ccgagtagcc cgcttccatc
    85861 gcgtctaatg agctttgagc ggaaactacg gcttgtttgt aggcgttaat gctactgata
    85921 gatgcattaa tgttgttgaa ggaggaacgc acggtctgca cgacgctacg atgggcactt
    85981 tccagttgct cgctggcacc gacaaagttg tactgtgcct gtttcacctg cgagttaacc
    86041 attccgccct gataaatcgg cagcgagaag ctcaggccaa ctttgttctg gcccatattg
    86101 ctatcgtcat actgggtacc agcggcacca cgggttttcg aaccgctata agaggtgtca
    86161 gaaatcccgg tagaagccgt taaatccaga gtcggtaagt gaccatcctg cgcctggcga
    86221 atttgctcgc gcgccaggtc ctggctcaag cgtgcctgta acagcgacag gttgcgtttt
    86281 tcggcttctt tcagcagcgc gttaaccggc tgtggtttgt cggttttaaa gttttcgaca
    86341 ttcagcgcag ccagttccgg atagtagtta ccggtgatct ggcgcagctg ctctaccgcg
    86401 ttatcaaggt tattacgtgc ggtcacttcg ttcgccagca cggtatcgta ctgtgcgcgg
    86461 gcgttctgca cgtcggtgat cgctaccagg cccacgttaa aacgttgggt ggtttgatct
    86521 aattgacggt agatcgcttc tttttgtgcc tgtgtatagg aaagaacgtc aatagcattc
    86581 aacacgttga aataagcggt cgcggtgttg aggatcaagg tttgctgatc ggtctgatgc
    86641 gtgacgtcct gaatccctgc tgctttttcc tgcagcgtta acgcacgcca tttcgacata
    86701 tcaaaaatgg attgagttaa ctgcaaggac gcactggtcg cgttagagtt gatgccgttc
    86761 gcgtcgcggt agccgttgct ataggtgtaa tctgcaccta aacctagctg tggcagtaat
    86821 ggactgcgcg cttcattaat tttttcaaag gcagcatcac gatcggcggc agacttacgc
    86881 aattccgggt tactaaggcg tgcttgctga taaacttgca tcaggttctc ggcctggctc
    86941 aacgaactga acccagaaag gctcaggccg ataagaatgg ggagcaattt cttcatttgc
    87001 attccttgtg gtgaagcagt atttagcgcg atcaaactgt aaaattattg cggattctag
    87061 cagaagccgc taccgcaaaa ggttggcgtt acgtgccata gggcgttaat gtgcctcaat
    87121 ttaacacatg actgctcaaa cggcagtcaa acgtcgctga aattcacatt taattcacta
    87181 ttagtgccag gacattaaca atgcttaagc cagacaacct gcccgttaca tttggcaaaa
    87241 acgatgtaga aattattgca cgagaaacac tttatcgcgg ctttttttca ttagatcttt
    87301 atagatttcg tcatcgtcta ttcaacgggc aaatgagtca tgaggtgcgg cgggaaattt
    87361 ttgagcgcgg tcacgccgca gtcttgctac cctttgaccc agtgcgtgat gaagttgtgc
    87421 tgattgagca gattcggatt gccgcgtacg acaccagcga aaccccttgg ctactggaga
    87481 tggttgccgg gatgattgaa gagggtgaaa gtgtggaaga tgttgcccgt cgcgaagcga
    87541 ttgaagaggc gggactgata gtcaaacgga ccaaaccggt gttaagtttc ctggcaagcc
    87601 cggggggcac cagtgagcgt tcgtcaatta tggtgggcga agtggacgcc acgaccgcaa
    87661 gcggtattca cggtctggct gatgaaaacg aagatattcg cgttcatgtg gtaagccggg
    87721 aacaggcata ccagtgggta gaagagggga aaatcgacaa cgcagcgtcg gtcatcgctt
    87781 tgcaatggct gcagctgcat catcaagcgt taaaaaatga gtgggcataa atgaagcgtt
    87841 acacacctga ctttcctgaa atgatgcgcc tgtgcgagat gaacttttca caattgcgcc
    87901 gtttgttacc gcgcaatgac gcacccggcg aaactgtaag ctatcaggtg gcaaacgcac
    87961 aatatcggct gacgattgtg gaatcgaccc gatacactac cctggtgaca atagaacaga
    88021 ctgcgcccgc gatcagttac tggagccttc cgtcaatgac ggtgcgtctg tatcatgacg
    88081 cgatggtggc tgaagtgtgt tcaagccagc agatttttcg cttcaaagcg cggtatgatt
    88141 atcctaataa aaagttgcat caacgcgacg aaaagcatca aattaatcag tttttagcgg
    88201 actggttgcg atactgttta gcacatggag cgatggcgat tccggtttat tagcgtcgtg
    88261 aaacctaagg acaccatttg gaaagcctgt taacccttcc tctggctggt gaggccagag
    88321 tcaggatttt acaaattacc gacactcacc tgtttgcaca aaagcacgaa gccctgttag
    88381 gggtaaacac ctgggagagt taccaggcgg tgctggaggc gattcggcca caccagcacg
    88441 aattcgacct gattgtcgcg acaggtgatt tagcgcagga tcaatcctct gcggcctatc
    88501 agcatttcgc tgaaggcatc gcaagttttc gtgcgccctg cgtctggctg ccgggcaacc
    88561 acgatttcca gcccgcgatg tacagcgcgt tacaggatgc gggtatctcc ccggcgaagc
    88621 gcgtgtttat tggtgagcaa tggcaaatcc tgttgctgga tagccaggtg tttggcgtgc
    88681 cgcacggtga gctgagcgag tttcagcttg agtggctgga acgtaaactg gccgatgcgc
    88741 cagaacgcca tacgttgctg ctgctgcatc atcatccgct acctgcgggt tgtagttggc
    88801 tcgatcaaca cagtctgcgt aacgcgggcg aactggatac cgtgctggcg aagtttccgc
    88861 acgtcaaata cttgctgtgc ggtcatattc atcaggagct ggatctcgac tggaatggtc
    88921 gccgcctgct ggcaacgccg tcgacctgtg tgcagtttaa gccgcactgt tccaacttta
    88981 cgctggatac catcgcgccc ggctggcgta ctctcgagtt acatgctgat ggcacgctga
    89041 ccaccgaggt gcatcgcctg gcggacacac gtttccaacc tgataccgct tcagaaggct
    89101 actgatgtct acgcttcttt atttacacgg tttcaacagc tcgccgcgct ctgcaaaagc
    89161 gagcttgtta aaaaactggc tggcggaaca tcaccctgac gttgagatga tcattccgca
    89221 gttgccgccg tatccttccg acgcggcaga gctgctggaa tccattgtcc tggaacatgg
    89281 cggtgattcg ctgggtattg tcggttcgtc actgggggga tattacgcca cctggttgtc
    89341 acaatgtttt atgctgcccg cagtggtggt aaacccggcg gtgcgcccgt ttgaactgct
    89401 gacggactat ctcggtcaga acgagaaccc ctacaccggg cagcaatatg tgctagagtc
    89461 acgccatatt tacgatctta aagtcatgca gattgacccg ctggaagcgc cggatttgat
    89521 ctggctgctg caacagacgg gagatgaagt gctggattac cgccaggcgg tggcgtacta
    89581 cgcttcctgc cgccagactg tcatagaagg cggcaaccac gcattcacgg gcttcgaaga
    89641 ttatttcaac ccgatcgtcg attttcttgg tctgcaccat ctctgacgat caactcgaat
    89701 tactaactta aaccatgacg caaacttata acgctgatgc cattgaggta ctcaccgggc
    89761 ttgagccggt tcgccgccgt ccggggatgt ataccgatac cactcgccct aaccatttgg
    89821 ggcaagaagt cattgataac agtgtggatg aagcactggc gggtcacgca aaacgcgtgg
    89881 acgttatttt acatgctgac cagtcgttag aagttattga cgatgggcgc gggatgccgg
    89941 tggatattca cccggaagag ggtgtaccgg cggttgaact gattctttgc cgtctgcatg
    90001 caggcggtaa attctctaac aaaaattacc agttctctgg cggcctgcat ggcgtgggga
    90061 tttcggtggt taacgccctg tcgaagcgcg tagaagttaa cgtgcgccgc gatggtcagg
    90121 tttataacat cgcctttgaa aatggcgaaa aggtgcagga tttacaggtt gtcggcactt
    90181 gcggtaaacg caatactggt accagtgtgc acttctggcc ggatgaaacc ttctttgaca
    90241 gcccgcgatt ttctgtttca cgcctgacgc atgtgctgaa agccaaagcg gtattgtgcc
    90301 ctggcgttga gatcactttt aaagatgaga tcaacaatac cgaacaacgc tggtgctatc
    90361 aggacggtct gaatgattac ctggcggaag cggtaaatgg tctgccgacg ctgccggaaa
    90421 aaccgtttat cggtaatttc gctggtgata ctgaagctgt ggactgggcg ctactgtggc
    90481 tgccggaagg cggtgaactg ctgaccgaaa gctacgtcaa ccttatccca acgatgcagg
    90541 gcggtaccca tgttaatggt ctgcgtcagg gcctgttgga cgcgatgcgt gagttctgtg
    90601 aataccgcaa tattctgccg cgcggtgtaa agctgtcggc ggaagatatc tgggatcgct
    90661 gcgcctatgt gctgtcagta aaaatgcagg atccgcagtt tgccgggcag acgaaagagc
    90721 gtctctcttc gcgtcaatgc gcggcattcg tttctggcgt ggtgaaagat gcctttatcc
    90781 tgtggctgaa ccagaacgtt caggcggctg aactgctggc ggagatggcg atttccagcg
    90841 cccagcgccg tatgcgtgcg gccaaaaaag tggtgcgtaa aaagctgacc agcggcccgg
    90901 cgttgcctgg caaactggct gattgtaccg cgcaggacct taaccgtacc gagctgttcc
    90961 ttgtggaagg tgactccgca ggcggatctg ccaagcaggc gcgcgatcgc gaatatcagg
    91021 cgatcatgcc actgaaaggt aagatcctta acacctggga agtctcttcc gacgaagtgc
    91081 tggctgcgca ggaagtgcac gatatttcgg tagcgatcgg tatcgatcct gacagcgacg
    91141 atctgagcca gcttcgttat ggcaaaatct gtatcctcgc ggatgcggac tctgatggtc
    91201 tgcacattgc cacgctgctc tgcgctttgt tcgtaaaaca tttccgcgcg ttggtgaaac
    91261 acggtcacgt ttacgtcgca ctgccaccgc tctaccgtat tgatctcggg aaagaggttt
    91321 attacgcgct gacggaagaa gagaaagagg gcgtacttga gcaattaaaa cgcaagaaag
    91381 gcaagccgaa cgtccagcgt tttaaaggtc tgggggaaat gaacccgatg caattgcgcg
    91441 aaaccacgct tgatccgaac actcgccgtc tggtgcagtt gactatcgat gatgaagacg
    91501 atcagcgtac tgacgcgatg atggatatgc tgctggcgaa gaaacgctcg gaagatcgcc
    91561 gcaactggtt gcaagagaaa ggcgacatgg cggagattga ggtttaaagg aaagaacatt
    91621 gcccggtcag gatggccggg caaacaaggc aggattaaat ccctggctgc agaatacgga
    91681 tattcatctc cagcacgtca ccttttacgg cttcgctata cgccttcatg tgcggggttt
    91741 gcagatgcgc ttcaagatgc gcgatgcttt cccactgctc aatcatcacg atagaatccg
    91801 gtgccataga ctggaaactc acgccagctg cgcaatccac cattggcgca tagccgtggc
    91861 aaccttcttc tttcagtacg gttggaacga ttttagcaaa ctgatccaat accgcctgac
    91921 ggtgatgttg accaggacga gtacggattt ctgcgattac ggtaagcatg gttaactcct
    91981 tctaaagcct gagctctagt taaccaaaaa tttccacaag atgcttgcga tattcttcag
    92041 tatagcgggg aacatcaggc atttttatca cgtcattagc gataaatgtc ggcagcggtt
    92101 ccataccgag gaattggttt gctttatgga acggcagata cacaccgtca acgccaacgc
    92161 cgtggaagaa ctgatctttt tcggtgaagg cttccattgg tgcgttccag gtcagagaaa
    92221 gcatatattt tttgccctgt accaggccgc cggaaccgta ttttttcgac ggatctttgc
    92281 gggtacgacc atcgctggca tacagcgtcc cgtgaccttc ggtgaataca tcatcaatgt
    92341 attttttcac tgtccacggc gcgcccatcc accagcctgg catctgccag atcaccacat
    92401 cagcccagag aaagttttgt acttccgctt tgacatcgta gtcgctgtcg gcgcgaacga
    92461 tgcggacatc atgcccaagg tcgcgcagtg tgccatccgc gacttcggtc agggtgtcgt
    92521 tcagttgacc attggagtgg gcgaattttt tcgcgccgtt gataatcagg atgttgctca
    92581 ttttttaacc tcaaggtgag acgtttgccg actatagtac gtcacagagc ggtacggtga
    92641 aattagcaaa atgtgcaaag tcttttgcga atttagcaaa agtctgatct tactctgact
    92701 caccgatgca ggataaatat tttctgaaaa tgacaatact gatagccatt cctcataatt
    92761 cttactcgca ccggaataat ttacacgttt ggttcggttt ttttggggat tgaaaatatg
    92821 gctttgaata agtaaaagat gaaagtatca acgtgtcatg ttgataatta taaatggatt
    92881 tttatgagcg tactgatata tgttaaagca gaaaattaaa acaatatttg aagcattgct
    92941 atatataatg cttacttatt ggttaataga ttcttttttt gctttcaata agtatgactg
    93001 gatgcttgag tcgggaggaa atatttgcag tataccttcc gtttcaggcg aagatcgtat
    93061 attgcaagca atgattgcag cattttttct tcttacgcca cttattgttc ttatcttaag
    93121 aaaactcttt atgcgggaaa tgttcgagtt ttgggtatat gtattctcgc tcggtatttg
    93181 tctggtttgt ggttggtggc ttttttgggg acggtttata ttttgctatt agtaaaatct
    93241 atgagagtcg ttttaacggc tctcatagac agagaagtta ccagcttacc ttcgcctcaa
    93301 atccaccttg ttccgcattc ccaaattcaa cattcatgcc atgcaatttg gcgattcgct
    93361 ggacaatcga tagcccaagc ccgctgccgg tagcggtttg tccgggtggg cgatagaagc
    93421 gttcgccaat tcgcgccagt gcctctggtg tcacaccggg gccgttatcc ctcacgatga
    93481 aattatcagc attcagcgtg acgtctacca cgctgccctg tggactgtag cgcacggcgt
    93541 tatccagcaa atttcgcacc aacaaactta gcaatagcgg ttgcccggtg cgtttgatgc
    93601 tgtgggcatt gagtgtcagt cgcacgtcaa ttttcgcctg ctgcgccgtg tggtaaatat
    93661 ccatcaccga cgattgcagg agatcttcaa gcgggatctc cgcgacgtcc tgaaggttat
    93721 ccagtgagtc cagccgcgat agcgtgagca gttgatcaac cagacgagta gcgcgatcga
    93781 tcccggaatg taattggagc agtgcttttt tccgcgcctg cggatcatcg tcagagagct
    93841 gcgcaacttc ggtttgcact ttcagcgccg ttaacgggct acgaagttcg tgagctgcgt
    93901 cggaggtaaa gcgtcgttca cgaaccatca tcgcatgtgt gcgggcgaac agttgattta
    93961 gcgactcaac cagtggccgc acttcgctgg gtacgccagt cgcgtttagt ggtttttccg
    94021 agtcagggtc acgcatacgt agtgccagcg ccagtttgtt cagcggcgcg agttcacgac
    94081 ccagtagtac catcatgatg attaacataa tcggcagtgc gaccagccac gggatcaatt
    94141 gcccggcaac aatcgccagc gccatgtctt cacggtattc ccattcctgg ccaacaacga
    94201 tgcgatattt gccatcaggt gaggtcatcc agacaaaacg ccaaggatcg tcttcaccga
    94261 ccagttgccc gtcagcaaaa ccttcccgtt gatagctata gggaatatct tctcc
//
LOCUS       DACAOP010000003        91155 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.003, whole genome shotgun sequence.
ACCESSION   DACAOP010000003 DACAOP010000000
VERSION     DACAOP010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 91155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91155
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.003"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..738)
                     /locus_tag="IT892_000186"
     CDS             complement(<1..738)
                     /locus_tag="IT892_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP3133441.1"
                     /translation="MIEEGLLLPMNVLLQGQKLTLLDPEMWFLRGNENKDVTLVITIG
                     NNHQKLMVVEDILLLIDRSQIEVTAGKVIYHPLRIDILSKLLAFIDESTGSVEREHHK
                     LFADALPFASEVVLFSKVASEAWFLATYLSSDNINEILFQHLRKTECYKLVRYLLSQS
                     LIQTSLYDLGELYGVSYSHFRRLCSYALGGKVKTELCGWRVARAVLEIIEGNSDMTTI
                     AHKYGYSSSSHFSAEVKSRLGKTPRELC"
     gene            complement(1084..1263)
                     /locus_tag="IT892_000187"
     CDS             complement(1084..1263)
                     /locus_tag="IT892_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GhoT/OrtT family toxin"
                     /protein_id="HAP3133442.1"
                     /translation="MINKLLLAYLIGLVVTSTLIFIFSEEKVTYRLFAAVITGLTWPL
                     SLIPSIISLMIRKSD"
     gene            complement(1329..2939)
                     /locus_tag="IT892_000188"
     CDS             complement(1329..2939)
                     /locus_tag="IT892_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133443.1"
                     /translation="MKGKSTLTLLLAGIFSCGTCQATGAEVTSESVFNILNSTGAATD
                     KSYLSLNPDKYPNYRLLIHSAKLKNEIKSHYTKDEIQGLLTLTENTRKLTLTEKPWGT
                     FILASTFEDDKTAAETHYDAVWLRDSLWGYMALVSDQGNSVAAKKVLLTLWDYMSTPD
                     QIKRMQDVISNPKRLDGISGQMNAVHIRFDSNSPVMADVQEEGKPQLWNHKQNDALGL
                     YLDLLIQAIDTGTINAEDWQKGDRLISIALLVAYLDKANFYVMEDSGAWEEDARLNTS
                     SVALVTSGLERLSNLLSKKDSVFISDLLREAKANELDEPLSTTRLNHLIDKGYERITL
                     QLDLGGESPGYLEKDKHYREADAALLNVIYPANLSKINTRRKEQVLKIVKKLAGPYGI
                     KRYEKDNYQSANFWFNDIKTDTDQNSHAKREMSFIPSTEAEWFFDSWYAKSAAIVYKE
                     SRKEEYLNDSVQFMNRSLAQITGENMIGANGRSVPEMALPESYNYIHKSGTLHEAPSP
                     IIPLNWSKASMTLMLKEMSNLINDEGIK"
     gene            complement(3172..3245)
                     /locus_tag="IT892_000189"
     tRNA            complement(3172..3245)
                     /locus_tag="IT892_000189"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3211..3213),aa:Gly,seq:ccc)
     gene            complement(3324..4076)
                     /locus_tag="IT892_000190"
     CDS             complement(3324..4076)
                     /locus_tag="IT892_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311765.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP3133444.1"
                     /translation="MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTV
                     KRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQKLKLGGAKSSSTRKSTAKSTTK
                     TASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYAA
                     GAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGSTD
                     AASVRLHFQIRYRATAIDPLRYLPPQGSKPKC"
     gene            4492..6789
                     /gene="xdhA"
                     /locus_tag="IT892_000191"
     CDS             4492..6789
                     /gene="xdhA"
                     /locus_tag="IT892_000191"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdenum-binding
                     subunit XdhA"
                     /protein_id="HAP3133445.1"
                     /translation="MEAREATATGESCMRVDAIAKVTGRARYTDDYVMAGMCYAKYVR
                     SPIAHGYAVSINDEQARSLPGVLAIFTWEDVPDIPFATAGHAWTLDENKRDTADRALL
                     TRHVRHHGDAVAIVVARDELTAEKAAQLVSIEWQELPVITTPEAALADDAEPIHNGGN
                     LLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMESVTSLAWMEDDSRITIVSST
                     QIPHIVRRVVGQALNIPWSCVRVIKPFVGGGFGNKQDVLEEPMAAFLTSKLGGIPVKV
                     SLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAGGN
                     KVAYLYPRCAYAYSSKTCYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEI
                     RLRNAAREGDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAECQNQQGNLRRGVGVA
                     CFSYTSNTWPVGVEIAGARLLMNQDGTINVQSGATEIGQGADTVFSQMVAETVGVPVS
                     DVRVISTQDTDITPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAAVMLHQSAMNL
                     TLIKGHIVLVERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPPAFGCTFVD
                     LTIDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGV
                     VRNPNLLDYKMPTMPDLPQLESAFVEINEPQSAYGHKSLGEPPIIPVAAAIRNAVKMA
                     TGVAINTLPLTPKRLYEEFHLAGLI"
     gene            6800..7678
                     /gene="xdhB"
                     /locus_tag="IT892_000192"
     CDS             6800..7678
                     /gene="xdhB"
                     /locus_tag="IT892_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase FAD-binding subunit XdhB"
                     /protein_id="HAP3133446.1"
                     /translation="MFDFASYHRAATLADAINLLTDNPQAKLLAGGTDVLIQLHHHND
                     RYRHIVDIHNLAELRGITLAEDGSLRIGSATTFTQLIEDPVTQRHLPALCAAASSIAG
                     PQIRNVATYGGNICNGATSADSATPTLIYDAKLEIHSPRGVRFVPINGFHTGPGKVSL
                     EHDEILVAFHFPPQPKEHAGSAHFKYAMRDAMDISTIGCAAHCRLDNGNFSELRLAFG
                     VAAPTPIRCQHAEQTAQNAPLNLQTLEAISESVLQDVAPRSSWRASKEFRLHLIQTMT
                     KKVISEAVAAAGGKLQ"
     gene            7675..8154
                     /gene="xdhC"
                     /locus_tag="IT892_000193"
     CDS             7675..8154
                     /gene="xdhC"
                     /locus_tag="IT892_000193"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase iron sulfur-binding
                     subunit XdhC"
                     /protein_id="HAP3133447.1"
                     /translation="MNHSETITIECTINGMPFQLHAAPGMPLSELLRDQGLLSVKQGC
                     CVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGAVQ
                     CGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK"
     gene            complement(8194..9972)
                     /locus_tag="IT892_000194"
     CDS             complement(8194..9972)
                     /locus_tag="IT892_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HAP3133448.1"
                     /translation="MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAG
                     TGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTP
                     VILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
                     IFATMIDNMDQGVLVVDDDNRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTH
                     GHMQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGEC
                     RVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPE
                     QLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAR
                     EILPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQED
                     IELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGE
                     VIDSTLLPPNLLNNGTTEQSDVTEVSEAHLALDDAGGTALEEMEKQMIREALSRHNSK
                     KQVADELGIGIATLYRKIKKYELLNT"
     gene            10451..11638
                     /gene="ygeW"
                     /locus_tag="IT892_000195"
     CDS             10451..11638
                     /gene="ygeW"
                     /locus_tag="IT892_000195"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="knotted carbamoyltransferase YgeW"
                     /protein_id="HAP3133449.1"
                     /translation="MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAAL
                     KALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGE
                     TVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC
                     DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFG
                     MDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKV
                     MEERTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADI
                     SGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQE
                     RVK"
     gene            11696..12892
                     /gene="dpaL"
                     /locus_tag="IT892_000196"
     CDS             11696..12892
                     /gene="dpaL"
                     /locus_tag="IT892_000196"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HAP3133450.1"
                     /translation="MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRP
                     TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSF
                     EHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAE
                     CIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMR
                     EMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIV
                     NVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRI
                     ISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEG
                     KHAVAP"
     gene            12950..14161
                     /locus_tag="IT892_000197"
     CDS             12950..14161
                     /locus_tag="IT892_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HAP3133451.1"
                     /translation="MAKNIPFKLILEKAKDYQADMTRFLRDMVAIPSESCDEKRVVHR
                     IKEEMEKVGFDKVEIDPMGNVLGYIGHGPRLVAMDAHIDTVGIGNIKNWDFDPYEGME
                     TDELIGGRGTSDQEGGMASMVYAGKIIKDLGLEDEYTLLVTGTVQEEDCDGLCWQYII
                     EQSGIRPEFVVSTEPTDCQVYRGQRGRMEIRIDVQGVSCHGSAPERGDNAIFKMGPIL
                     GELQELSQRLGYDEFLGKGTLTVSEIFFTSPSRCAVADSCAVSIDRRLTWGETWEGAL
                     DEIRALPAVQKANAVVSMYNYDRPSWTGLVYPTECYFPTWKVEEDHFTVKALVNAYEG
                     LFGKAPVVDKWTFSTNGVSIMGRHGIPVIGFGPGKEPEAHAPNEKTWKSHLVTCAAMY
                     AAIPLSWLATE"
     gene            14214..15599
                     /locus_tag="IT892_000198"
     CDS             14214..15599
                     /locus_tag="IT892_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311773.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-phenylhydantoinase"
                     /protein_id="HAP3133452.1"
                     /translation="MRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEI
                     DATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCR
                     LRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKL
                     NDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAE
                     AIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYD
                     TEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCP
                     NGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVV
                     IIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRF
                     LRRKPFVPPVL"
     gene            15647..16579
                     /gene="arcC"
                     /locus_tag="IT892_000199"
     CDS             15647..16579
                     /gene="arcC"
                     /locus_tag="IT892_000199"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAP3133453.1"
                     /translation="MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIV
                     THGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGI
                     NKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAEQLTKQGYTLKEDAGRGYRRVV
                     ASPKPVDIIEKETVKALVDAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLA
                     EMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAA
                     ASFARSRAGREALITVLSKAKEGIEGKTGTVICQ"
     gene            complement(16621..18246)
                     /locus_tag="IT892_000200"
     CDS             complement(16621..18246)
                     /locus_tag="IT892_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HAP3133454.1"
                     /translation="MNIFTEAAKLEEQNCPFAMAQIVDSRGSTPRHSAQMLVRADGSI
                     VGTIGGGMVERKVIEESLQALQERKPRLFHGRMARNGADAVGSDCGGAMSVFISVHGM
                     RPRLVLIGAGHVNRAIAQSAALLGFDIAVADIYRESLNPELFPPSTTLLHAESFGAAV
                     EALDIRPDNFVLIATNNQDREALDKLIEQPIAWLGLLASRRKVQLFLRQLREKGVAEE
                     HIARLHAPVGYNIGAETPQEIAISVLAEILQVKNNAPGGLMMKPSHPSGHQLVVIRGA
                     GDIASGVALRLYHAGFKVIMLEVEKPTVIRCTVAFAQAVFDGEMTVEGVTARLATSSA
                     EAMKLTERGFIPVMVDPACSLLDELKPLCVVDAILAKQNLGTRADMAPVTIALGPGFI
                     AGKDCHAVIETNRGHWLGQVIYSGCAQENTGVPGNIMGHTTRRVIRAPAAGIMRSNVK
                     LGDLVKEGDVIAWIGEHEIKAPLTGMVRGLLNDGLAVVGGFKIGDIDPRGETADFTSV
                     SDKARAIGGGVLEALMMLMHQGVKATKEVLEVA"
     gene            complement(18294..19064)
                     /gene="yqeC"
                     /locus_tag="IT892_000201"
     CDS             complement(18294..19064)
                     /gene="yqeC"
                     /locus_tag="IT892_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HAP3133455.1"
                     /translation="MKSIVDPSALFIDLGAQKRPTVISVVGAGGKTSLLFWLAELLQA
                     SGRRVLITTTTHMFMPTSHWPVVFCRDPAMLPHASLTSPISFCFHSWKANQGKVQGFT
                     PEAIDALVQRPECDVILIEADGSRGMPLKAPDEHEPCIPKSSCCVIAVMGGHILGAKV
                     STENVHRWSQFADITGLTPDAPLQLSDLVALVRHPQGAFKNVPQGCRRVWFINRFSQC
                     ENAIAQSELLQPLQQHNVEAIWLGDIQEHPAIARRFVN"
     gene            19167..19745
                     /gene="mocA"
                     /locus_tag="IT892_000202"
     CDS             19167..19745
                     /gene="mocA"
                     /locus_tag="IT892_000202"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HAP3133456.1"
                     /translation="MSAIDCIITAAGLSSRMGQWKMMLPWQQGTILDTSIKNALQFCS
                     RIILVTGYRGNELHERYANQSNITIIHNPDYAQGLLTSVKAAVPAVKTEYCFLTHGDM
                     PTLTIDIFRKIWSLRNDGAILPLHNGIPGHPILVSKPCLMQAIQRPNITNMRQALLMG
                     DHYSVEIENAEIILDIDTPDDFITAQKRYTKI"
     gene            20067..23165
                     /gene="ygfK"
                     /locus_tag="IT892_000203"
     CDS             20067..23165
                     /gene="ygfK"
                     /locus_tag="IT892_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenate reductase subunit YgfK"
                     /protein_id="HAP3133457.1"
                     /translation="MGDIMRPIPFEELLTRIFDEYQQQRSIFGIPEQQFYSPVKGKTV
                     SVFGETCATPVGPAAGPHTQLAQNIVTSWLTGGRFIELKTVQILDRLELEKPCIDAED
                     ECFNTEWSTEFTLLKAWDEYLKAWFALHLLEAMFQPSDSGKSFIFNMSVGYNLEGIKQ
                     PPMQQFIDNMMDASDHPKFAQYRDTLNKLLQDDAFLARHGLQEKRECLQALPARIPTS
                     MVQGVTLSTMHGCPPHEIEAICRYMLEEKGLNTFVKLNPTLLGYARVREILDVCGFGY
                     IGLKEESFDHDLKLTQALEMLERLMVLAKEKSLGFGVKLTNTLGTINNKGALPGEEMY
                     MSGRALFPLSINVAAVLSRAFDGKLPISYSGGASQLTIRDIFDTGIRPITMATDLLKP
                     GGYLRLSACMRELEGSDAWGLDHVDVERLNKLAADALTMEYTQKHWKPEERIEVAEDL
                     PLTDCYVAPCVTACAIKQDIPEYIRLLGEHRYADALELIYQRNALPAITGHICDHQCQ
                     YNCTRLDYDSALNIRELKKVALEKGWDEYKQRWHKPAGSGSRHPVAVIGAGPAGLAAG
                     YFLARAGHPVTLFEREANAGGVVKNIIPQFRIPAELIQHDIDFVAAHGVKFEYGCSPD
                     LTVEQLKNQGFHYVLIATGTDKNSGVKLAGDNQNVWKSLPFLREYNKGTALKLGKHVV
                     VVGAGNTAMDCARAALRVPGVEKATVVYRRSLQEMPAWREEYEEALHDGVEFRFLNNP
                     ERFDADGTLTLRVMSLGEPDEKGRRRPVETNETVTLHVDSLITAIGEQQDTEALNAMG
                     VPLDKNGWPDVDHNGETRLTDVFMIGDVQRGPSSIVAAVGTARRATDVILSRENIRSH
                     QNDKYWNNVNPAEIYQRKGDISITLVDSDDRDAFVAQEAARCLECNYVCSKCVDVCPN
                     RANVSIAVPGFQNRFQTLHLDAYCNECGNCAQFCPWNGKPYKDKITVFSLSQDFDNSS
                     NPGFLVEDCRVRVRLNNQSWVLNIDSEGQFNNVPPELNDMCRIISHVHQHHHYLLGRV
                     EV"
     gene            23168..24496
                     /gene="ssnA"
                     /locus_tag="IT892_000204"
     CDS             23168..24496
                     /gene="ssnA"
                     /locus_tag="IT892_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HAP3133458.1"
                     /translation="MLILKNVTAVQLHPAKVQEGVDIAIENDVIVAIGDALTQRYPDA
                     SYKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCPDFISTLKNLWWRLDRALDEES
                     LYYSGLICSLEAIKSGCTSVIDHHASPAYIGGSLSTLRNAFLKVGLRAMTCFETTDRN
                     NGIKELQEGVEENIRFARQIDEAKKAATEPYLVEAHIGAHAPFTVPDAGLEMLREAVK
                     ATGRGLHIHAAEDLYDVSYSHHWYGKDLLARLAQFDLIDSKTLVAHGLYLSKDDIALL
                     NQRDAFLVHNARSNMNNHVGYNHHLSDIRNLALGTDGIGSDMFEEMKFAFFKHRDAGG
                     PLWPDSFAKALANGNELMSRNFGAKFGLLEAGYKADLTICDYNSPTPLLADNIAGHIA
                     FGMGSGSVHSVMVNGVMVYEDRQFNFDCDSIYAQARKAAASMWRRMDALA"
     gene            24547..25326
                     /locus_tag="IT892_000205"
     CDS             24547..25326
                     /locus_tag="IT892_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     FAD-binding subunit"
                     /protein_id="HAP3133459.1"
                     /translation="MIEQFFRPDSVEQALELKRRYKDEAVWFAGGSKLNATPTRTDKK
                     IAISLQDLELDWVDWDNGALRIGAMSRLQPLRDARFIPAALREALGFVYSRHVRNQST
                     IGGEIAARQEESVLLPVLLALDAELVFGNGETLSIEDYLACPCDRLLTEIIIKDPYRT
                     CATRKISRSQAGLTVVTAAVAMTDHDGMRIALDGVASKALRLHDVEKQNLEGNALEQA
                     VANAIFPQEDLRGSVAYKRYITGVLVADLYADCQQAGEEAV"
     gene            25323..28193
                     /locus_tag="IT892_000206"
     CDS             25323..28193
                     /locus_tag="IT892_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     Mo/Fe-S-binding subunit"
                     /protein_id="HAP3133460.1"
                     /translation="MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFA
                     GSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYND
                     PAAALIITDLLDRIDAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATID
                     IAPTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHL
                     DVSKAEALPGVVHVITHLNCPDIYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVV
                     AESEEIALEALKLIDVEYEVLKPVMSIDEAMAEDAPVVHDEPVVYVAGAPDTLEDDNS
                     HAAQRGEHMIINFPIGSRPRKNIAASIHGHIGDMDKGFADADVIIERTYNSTQAQQCP
                     TETHICFTRMDGDRLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQD
                     ILLEEVCAWATCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDF
                     RANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYGAPKGNF
                     AITMALAELAEQLQIDQLEIIERNRVHEGQELKILGAIGEGKAPTSVPSAASCALEEI
                     LRQGREMIQWSSPKPQNGDWHIGRGVAIIMQKSGIPDIDQANCMIKLESDGTFIVHSG
                     GADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARL
                     AAENLREKILFHGAQMLGEPVADVQLATPGVVRGKKGEVSFGDIAHKGETGTGFGSLV
                     GTGSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGAT
                     LRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLVPSDDKVGPFGAKS
                     ISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI"
     gene            28358..29758
                     /gene="xanQ"
                     /locus_tag="IT892_000207"
     CDS             28358..29758
                     /gene="xanQ"
                     /locus_tag="IT892_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanQ"
                     /protein_id="HAP3133461.1"
                     /translation="MSDINHAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPAL
                     IVGAALQLSAETTAYLVSMAMIASGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIA
                     LGSSMKSDGFHEELIMSSLLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGL
                     SLIKVGIIDFGGGFAAKSSGTFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGL
                     CVGYIASLCLGMVDFSSMRNLPLITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGD
                     ITATAMVSRRPIQGEEYQSRLKGGVLADGLVSVIASAVGSLPLTTFAQNNGVIQMTGV
                     ASRYVGRTIAVMLVILGLFPMIGGFFTTIPSAVLGGAMTLMFSMIAIAGIRIIITNGL
                     KRRETLIVATSLGLGLGVSYDPEIFKILPASIYVLVENPICAGGLTAILLNIILPGGY
                     RQENVLPGITSEEEMD"
     gene            29776..31092
                     /gene="guaD"
                     /locus_tag="IT892_000208"
     CDS             29776..31092
                     /gene="guaD"
                     /locus_tag="IT892_000208"
                     /EC_number="3.5.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HAP3133462.1"
                     /translation="MSGEHTLKAVRGSFIDVTRTVDNPEEIASALRFIEDGLLLIKQG
                     KVEWFGEWEDGKHQIPDTIRVRDYRGKLIVPGFVDTHIHYPQSEMVGAYGEQLLEWLN
                     KHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINM
                     RMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQM
                     AMAKRLKEEYPDTWVHTHLCENKDEIAWVKELYPEHDGYLDVYHQYGLTGKNCVFAHC
                     VHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFN
                     MLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEP
                     TATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN"
     gene            31128..32495
                     /locus_tag="IT892_000209"
     CDS             31128..32495
                     /locus_tag="IT892_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP3133463.1"
                     /translation="MSGDILQTPDAPKSQGALDNYFKITARGSTVRQEVLAGLTTFLA
                     MVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLLMGLWANLPMAIGCAISLTAFTA
                     FSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
                     LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIA
                     ISIIGLIFDPAVKYHGLVAMPSLTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVF
                     DATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGAAPAAVYIESAAGTA
                     AGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFI
                     DAMAGLVCAVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYA
                     GGWAI"
     gene            complement(32531..33019)
                     /locus_tag="IT892_000210"
     CDS             complement(32531..33019)
                     /locus_tag="IT892_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417362.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAP3133464.1"
                     /translation="MKSLIIVNPADCIGCRTCEVACVVAHPSEQELNADVFLPRLKVQ
                     RLDCISAPVMCHQCENAPCVGACPVGALTMGEQVVQANSARCIGCQSCVSACPFGMIT
                     IQSLPGDTRQQIVKCDLCEQREEGPACVESCPTQALQLLTERELRRVRQQRIVASGEN
                     PL"
     gene            complement(33019..34938)
                     /gene="ygfT"
                     /locus_tag="IT892_000211"
     CDS             complement(33019..34938)
                     /gene="ygfT"
                     /locus_tag="IT892_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     YgfT"
                     /protein_id="HAP3133465.1"
                     /translation="MNKFIAAEAAECIGCHACEIACAMAHNQENWPLSHSDFRPRIHV
                     VGKGQAANPVACHHCNNAPCVTACPVNALTFQPDSVQLDEQKCIGCKRCAIACPFGVV
                     EMVDTIAQKCDLCNQRSSGTQACIEVCPTQALRLMDDKGLQQIKVARQRKTAAGKASS
                     DAQPSRSAALLPVNSRKGADKISASERKTHFGEIYYGLDPQQATYESDRCVYCAEKAN
                     CNWHCPLHNAIPDYIRLVQEGKIIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKD
                     HSGAVSIGNLERYITDTALAMGWRPDVSKVVPRIEKVAVIGAGPAGLGCADILARAGV
                     QVDVFDRHPEIGGMLTFGIPPFKLDKTVLSQRREIFTAMGIDFHLNCEIGRDITFSDL
                     TSEYDAVFIGVGTYGMMRADLPHEDAPGVIQALPFLTAHTRQLMGLPESEEYPLTDVE
                     GKRVVVLGGGDTTMDCLRTSIRLNAVSVTCAYRRDEVSMPGSRKEVVNAREEGVEFQF
                     NVQPQYIACDEDGRLTAVGLIRTAMGEPGPDGRRRPRPVAGSEFELPADVLIMAFGFQ
                     AHAMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHLKKVFAGGDAVHGADLVVTAMAAGR
                     QAARDMLTLFDTKAW"
     gene            35374..36822
                     /locus_tag="IT892_000212"
     CDS             35374..36822
                     /locus_tag="IT892_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAP3133466.1"
                     /translation="MSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAG
                     AVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFA
                     AVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGL
                     SIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFG
                     FLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFL
                     ALGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVC
                     ISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYN
                     LYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHAD
                     LVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE"
     gene            36824..36949
                     /locus_tag="IT892_000213"
     CDS             36824..36949
                     /locus_tag="IT892_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133467.1"
                     /translation="MNLLMRAIFSLLLLFTLSIPVISDCVAMAIESRFKYMMLLF"
     gene            complement(36946..37017)
                     /locus_tag="IT892_000214"
     CDS             complement(36946..37017)
                     /locus_tag="IT892_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133468.1"
                     /translation="MINQVSVYRQPPVLSGCRQVKTI"
     gene            37072..37620
                     /gene="idi"
                     /locus_tag="IT892_000215"
     CDS             37072..37620
                     /gene="idi"
                     /locus_tag="IT892_000215"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAP3133469.1"
                     /translation="MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKG
                     QLLVTRRALSKKAWPGVWTNSVCGHPQQGESNEDAVIRRCRYELGVEITPPESIYPDF
                     RYRATDPNGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLRGIDATPWAFSP
                     WMVMQAANSEARKLLSAFAQHN"
     gene            complement(37663..39180)
                     /gene="lysS"
                     /locus_tag="IT892_000216"
     CDS             complement(37663..39180)
                     /gene="lysS"
                     /locus_tag="IT892_000216"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAP3133470.1"
                     /translation="MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDH
                     TSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGA
                     AARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAG
                     DDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK"
     gene            complement(39190..40288)
                     /gene="prfB"
                     /locus_tag="IT892_000217"
     CDS             complement(join(39190..40212,40214..40288))
                     /gene="prfB"
                     /locus_tag="IT892_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311790.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAP3133471.1"
                     /translation="MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQP
                     DVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAE
                     LDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRG
                     FKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFS
                     SAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQN
                     DRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIK
                     DLRTGVETRNTQAVLDGSLDQFIEASLKAGL"
     gene            complement(40379..42112)
                     /gene="recJ"
                     /locus_tag="IT892_000218"
     CDS             complement(40379..42112)
                     /gene="recJ"
                     /locus_tag="IT892_000218"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAP3133472.1"
                     /translation="MKQQIQLRRREVDETADLPAELPPLLRRLYASRGVRSAQELKRS
                     VKGMLPWQQLSGVEKAVEILYNAFREGTRIIVVGDFDADGATSTALSVLAMRSLGCSN
                     IDYLVPNRFEDGYGLSPEVVDQAHARGAQLIVTVDNGISSHAGVEHARSLGIPVIVTD
                     HHLPGDTLPAAEAIINPNLRDCNFPSKSLAGVGVAFYLMLALRTFLRDQGWFDERGIA
                     IPNLAELLDLVALGTVADVVPLDANNRILTWQGMSRIRAGKCRPGIKALLEVANRDAQ
                     KLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNIGEARVLANELDALNQTRKEIEQ
                     GMQVEALTLCEKLERSRDTLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAG
                     DGTLKGSGRSIQGLHMRDALERLDTLYPGMMLKFGGHAMAAGLSLEEDKFELFQQRFG
                     ELVTEWLDPSLLQGEVVSDGPLSPAEMTMEVAQLLRDAGPWGQMFPEPLFDGHFRLLQ
                     QRLVGERHLKVMVEPVGGGPLLDGIAFNVDTALWPDNGVREVQLAYKLDINEFRGNRS
                     LQIIIDNIWPI"
     gene            complement(42118..42828)
                     /gene="dsbC"
                     /locus_tag="IT892_000219"
     CDS             complement(42118..42828)
                     /gene="dsbC"
                     /locus_tag="IT892_000219"
                     /EC_number="5.3.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein-disulfide
                     isomerase/oxidoreductase DsbC"
                     /protein_id="HAP3133473.1"
                     /translation="MKKGFMLFTLLAAFSGFAQADDAAIQQTLAKMGIKSSDIQPAPV
                     AGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPVNVTNKMLLKQLNALEKEMIVYK
                     APQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLESQAEQQMKAIW
                     CAKDKNKAFDDVMAGKAATPASCDIDIADHYALGVQLGVSGTPAIVLSNGTLVPGYQP
                     PKDMKEFLDEHQKMTSGK"
     gene            complement(42853..43749)
                     /gene="xerD"
                     /locus_tag="IT892_000220"
     CDS             complement(42853..43749)
                     /gene="xerD"
                     /locus_tag="IT892_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAP3133474.1"
                     /translation="MKQDLARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRG
                     LTLATAQSDDLQALLAERLEGGYKATSSARLLSAVRRLFQYLYREKFREDDPSAHLAS
                     PKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
                     SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQM
                     TRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTT
                     QIYTHVATERLRQLHQQHHPRA"
     gene            43861..44382
                     /gene="fldB"
                     /locus_tag="IT892_000221"
     CDS             43861..44382
                     /gene="fldB"
                     /locus_tag="IT892_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldB"
                     /protein_id="HAP3133475.1"
                     /translation="MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLME
                     QYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALG
                     ILHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQNW
                     CEQILNEMAEHYA"
     gene            complement(44422..44829)
                     /locus_tag="IT892_000222"
     CDS             complement(44422..44829)
                     /locus_tag="IT892_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133476.1"
                     /translation="MVLWQSDLRVSWRAQWLSLLIHGLVAAVILLMPWPLSYTPLWMV
                     LLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQEWSIVKAPWMIKSGMMLRLRSD
                     SGKRQHLWLAADSMDEAEWRDLRRILLQQETQR"
     gene            complement(44810..45076)
                     /gene="sdhE"
                     /locus_tag="IT892_000223"
     CDS             complement(44810..45076)
                     /gene="sdhE"
                     /locus_tag="IT892_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD assembly factor SdhE"
                     /protein_id="HAP3133477.1"
                     /translation="MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFI
                     RLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRNRERGPVAI"
     gene            45319..46299
                     /gene="ygfZ"
                     /locus_tag="IT892_000224"
     CDS             45319..46299
                     /gene="ygfZ"
                     /locus_tag="IT892_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-modifying protein YgfZ"
                     /protein_id="HAP3133478.1"
                     /translation="MAFTPFPPRQPTASARLPLTLITLDDWALATITGADSEKYMQGQ
                     VTADVSQMTENQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYA
                     VFSKVTIAPDDERVLLGVAGFQARAALANIFSELPSKEKQVVKEGATTLLWFEHPAER
                     FLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQA
                     LGGISFKKGCYTGQEMVARAKFRGANKRALWLLTGSASRLPEAGEDLELKMGENWRRT
                     GTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE"
     gene            complement(46376..47035)
                     /locus_tag="IT892_000225"
     CDS             complement(46376..47035)
                     /locus_tag="IT892_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP3133479.1"
                     /translation="MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDL
                     NASATAITSYSLYGGSMILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPF
                     LLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
                     IKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQ
                     A"
     gene            complement(47199..47510)
                     /locus_tag="IT892_000226"
     CDS             complement(47199..47510)
                     /locus_tag="IT892_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAP3133480.1"
                     /translation="MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRF
                     EDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLLELKKVIADIYPGQTQFYVIEFKC
                     L"
     gene            47555..48988
                     /locus_tag="IT892_000227"
     CDS             47555..48988
                     /locus_tag="IT892_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311800.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP3133481.1"
                     /translation="MKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHG
                     VPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEA
                     QPNEEGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAE
                     VVFERYKYKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFV
                     ASALAVKAARRINPEMKVGCMLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGY
                     YPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFE
                     GSVPNPYVKASDWGWQIDPVGLRYALCELYERYQKPLFIVENGFGAYDKMEEDGSIND
                     DYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDD
                     GTGDMSRSRKKSFDWYKEVIASNGEKL"
     gene            complement(49152..52025)
                     /gene="gcvP"
                     /locus_tag="IT892_000228"
     CDS             complement(49152..52025)
                     /gene="gcvP"
                     /locus_tag="IT892_000228"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HAP3133482.1"
                     /translation="MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQ
                     IVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNM
                     LENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
                     AKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQ
                     QVGTTGEIHDYTTLISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVP
                     MGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNI
                     CTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLC
                     VEVADKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLDID
                     TLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIP
                     LGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVC
                     MQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVAC
                     DKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDG
                     ANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVV
                     QIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQD
                     AFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLM
                     VEPTESESKVELDRFIDAMLAIRAEIDQVKAGAWPLEDNPLVNAPHIQSELVAEWAHP
                     YSREIAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ"
     gene            complement(52144..52533)
                     /gene="gcvH"
                     /locus_tag="IT892_000229"
     CDS             complement(52144..52533)
                     /gene="gcvH"
                     /locus_tag="IT892_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HAP3133483.1"
                     /translation="MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVD
                     LPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWI
                     FKIKASDESELESLLDATAYEALLEDE"
     gene            complement(52557..53651)
                     /gene="gcvT"
                     /locus_tag="IT892_000230"
     CDS             complement(52557..53651)
                     /gene="gcvT"
                     /locus_tag="IT892_000230"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HAP3133484.1"
                     /translation="MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDA
                     GMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVY
                     YFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLF
                     NDAQRHAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKP
                     CGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREH
                     GTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGI
                     GETAIVQIRNREMPVKVTKPVFVRNGKAVA"
     gene            53942..54025
                     /locus_tag="IT892_000231"
     CDS             53942..54025
                     /locus_tag="IT892_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133485.1"
                     /translation="MSKNTKSKIRGIRKYNAKTEVKLVYFK"
     gene            complement(54099..55301)
                     /gene="ubiI"
                     /locus_tag="IT892_000232"
                     /gene_synonym="visC"
     CDS             complement(54099..55301)
                     /gene="ubiI"
                     /locus_tag="IT892_000232"
                     /gene_synonym="visC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent 2-octaprenylphenol hydroxylase"
                     /protein_id="HAP3133486.1"
                     /translation="MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADA
                     PPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYS
                     HLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
                     IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLS
                     DPHLCSIVWSLSPEEAQRMQQASEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYA
                     RQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRR
                     YERSRKHSAALMLAGMQGFRDMFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGL
                     NDLPEWLR"
     gene            complement(55324..56502)
                     /gene="ubiH"
                     /locus_tag="IT892_000233"
                     /gene_synonym="visB"
     CDS             complement(55324..56502)
                     /gene="ubiH"
                     /locus_tag="IT892_000233"
                     /gene_synonym="visB"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="HAP3133487.1"
                     /translation="MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPG
                     FDGRAIALAAGTCQQLARIGVWQSLADCATAITSVHVSDRGHAGFVTLAAEDYQLAAL
                     GQVVELHNVGQRLFALLRKAPGVTLHCPDRVANVARTQSHVEVTLECGETLTGRVLVA
                     ADGTHSALATVCGVDWQQEPYEQLAVIANVATSVAHEGRAFERFTQHGPLAMLPMSDG
                     RCSLVWCHLLERREEVLSWSDEKFCRELQSAFGWRLGKITHAGKRSAYPLALTRAARP
                     ITHRTVLVGNAAQTLHPIAGQGFNLGMRDVMSLAETLTQAQERGEDIGDYGVLCRYQQ
                     RRQSDREATIGVTDSLVHLFANRWTPLVVGRNIGLMTMELFTPARDVLAQRTLGWVAR
                     "
     gene            complement(56499..57824)
                     /gene="pepP"
                     /locus_tag="IT892_000234"
     CDS             complement(56499..57824)
                     /gene="pepP"
                     /locus_tag="IT892_000234"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="HAP3133488.1"
                     /translation="MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPY
                     RQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEK
                     LGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADEIVNSALEKLRKGSRQNLTAP
                     ATMIDWRPIVHEMRLFKSPEEIAVLRRAGEITALAHTRAMEKCRPGMFEYHLEGEIHH
                     EFNRHGARYPSYNTIVGSGENGCILHYTENESELRDGDLVLIDAGCEYKGYAGDITRT
                     FPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSMQEVTGEVVRIMVSGLVKLGILKG
                     DVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPD
                     ADVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMAAARKQ"
     gene            complement(57850..58428)
                     /gene="ygfB"
                     /locus_tag="IT892_000235"
     CDS             complement(57850..58428)
                     /gene="ygfB"
                     /locus_tag="IT892_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YgfB"
                     /protein_id="HAP3133489.1"
                     /translation="MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDS
                     SWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRA
                     DALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEE
                     IIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH"
     gene            58596..58925
                     /gene="zapA"
                     /locus_tag="IT892_000236"
     CDS             58596..58925
                     /gene="zapA"
                     /locus_tag="IT892_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAP3133490.1"
                     /translation="MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKER
                     TRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITE
                     KTNQNFE"
     gene            58967..59150
                     /gene="ssrS"
                     /locus_tag="IT892_000237"
     ncRNA           58967..59150
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IT892_000237"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            59171..59773
                     /locus_tag="IT892_000238"
     CDS             59171..59773
                     /locus_tag="IT892_000238"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAP3133491.1"
                     /translation="MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMM
                     TYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQ
                     SELVMNRLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
                     HYKMQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW"
     gene            complement(59874..59933)
                     /gene="ibsC"
                     /locus_tag="IT892_000239"
     CDS             complement(59874..59933)
                     /gene="ibsC"
                     /locus_tag="IT892_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsC"
                     /protein_id="HAP3133492.1"
                     /translation="MMRLVIILIVLLLISFPAY"
     gene            complement(60162..61394)
                     /locus_tag="IT892_000240"
     CDS             complement(60162..61394)
                     /locus_tag="IT892_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAP3133493.1"
                     /translation="MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDD
                     EQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVF
                     NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
                     HIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTK
                     NMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDP
                     FTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL
                     HGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEK
                     ALQAMKAIPGTIRARLLY"
     gene            complement(61650..62309)
                     /gene="rpiA"
                     /locus_tag="IT892_000241"
     CDS             complement(61650..62309)
                     /gene="rpiA"
                     /locus_tag="IT892_000241"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAP3133494.1"
                     /translation="MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKG
                     QIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTR
                     EKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGV
                     VTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIV
                     K"
     gene            complement(62365..62595)
                     /locus_tag="IT892_000242"
     CDS             complement(62365..62595)
                     /locus_tag="IT892_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001328908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133495.1"
                     /translation="MHFAQRVRALVVLNGVALLPQFACKQGLVNGELVRLFAPWSGIP
                     RLLHALFAGRKGMPAIARYFMDELTTRLANGV"
     gene            62737..63630
                     /locus_tag="IT892_000243"
     CDS             62737..63630
                     /locus_tag="IT892_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator ArgP"
                     /protein_id="HAP3133496.1"
                     /translation="MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLEN
                     MFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSL
                     ATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
                     ALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPC
                     HIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPES
                     RMMRKVTDALLDYGHKVLRQD"
     gene            63834..65978
                     /gene="scpA"
                     /locus_tag="IT892_000244"
     CDS             63834..65978
                     /gene="scpA"
                     /locus_tag="IT892_000244"
                     /EC_number="5.4.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase"
                     /protein_id="HAP3133497.1"
                     /translation="MSNVQEWQQLANKELSRREKTVDSLVHQTAEGIAIKPLYTEADL
                     DNLEVTGTLPGLPPYVRGPRATMYTAQPWTIRQYAGFSTAKESNAFYRRNLAAGQKGL
                     SVAFDLATHRGYDSDNPRVAGDVGKAGVAIDTVEDMKVLFDQIPLDKMSVSMTMNGAV
                     LPVLAFYIVAAEEQGVTPDKLTGTIQNDILKEYLCRNTYIYPPKPSMRIIADIIAWCS
                     GNMPRFNTISISGYHMGEAGANCVQQVAFTLADGIEYIKAAISAGLKIDDFAPRLSFF
                     FGIGMDLFMNVAMLRAARYLWSEAVSGFGAQDPKSLALRTHCQTSGWSLTEQDPYNNV
                     IRTTIEALAATLGGTQSLHTNAFDEALGLPTDFSARIARNTQIIIQEESELCRTVDPL
                     AGSYYIESLTDQIVKQARAIIQQIDEAGGMAKAIEAGLPKRMIEEASAREQSLIDQGK
                     RVIVGVNKYKLDHEDETDVLEIDNVMVRNEQIASLERIRATRDDAAVTAALNALTHAA
                     QHNENLLAAAVNAARVRATLGEISDALEVAFDRYLVPSQCVTGVIAQSYHQSEKSASE
                     FDAIVAQTEQFLADNGRRPRILIAKMGQDGHDRGAKVIASAYSDLGFDVDLSPMFSTP
                     EEIARLAVENDVHVVGASSLAAGHKTLIPELVEALKKWGREDICVVAGGVIPPQDYAF
                     LQERGVAAIYGPGTPMLDSVRDVLNLISQHHD"
     gene            65971..66966
                     /gene="meaB"
                     /locus_tag="IT892_000245"
     CDS             65971..66966
                     /gene="meaB"
                     /locus_tag="IT892_000245"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl Co-A mutase-associated GTPase
                     MeaB"
                     /protein_id="HAP3133498.1"
                     /translation="MINEATLAESIRRLRQGERATLAQAMTLVESRHPRHQALSTQLL
                     DAIMPYCGNTLRLGVTGTPGAGKSTFLEAFGMLLIREGLKVAVIAVDPSSPVTGGSIL
                     GDKTRMNDLARAEAAFIRPVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQS
                     ETEVARMVDCFISLQIAGGGDDLQGIKKGLMEVADLIVINKDDGDNHTNVAIARHMYE
                     SALHILRRKYDEWQPRVLTCSALEKRGIDEIWHAIIDFKTALTASGRLQQVRQQQSVE
                     WLRKQTEEEVLNHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQLSEFIQTQYFD"
     gene            66977..67762
                     /gene="scpB"
                     /locus_tag="IT892_000246"
     CDS             66977..67762
                     /gene="scpB"
                     /locus_tag="IT892_000246"
                     /EC_number="7.2.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA decarboxylase"
                     /protein_id="HAP3133499.1"
                     /translation="MSYQYVNVVTINKVAVIEFNYGRKLNALSKVFIDDLMQALSDLN
                     RPEIRCIILRAPSGSKVFSAGHDIHELPSGGRDPLSYDDPLRQITRMIQKFPKPIISM
                     VEGSVWGGAFEMIMSSDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKEL
                     IFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEELRVLGE
                     AHTMNSDEFERIQGMRRAVYDSEDYQEGMNAFLEKRKPNFVGH"
     gene            67786..69264
                     /gene="scpC"
                     /locus_tag="IT892_000247"
     CDS             67786..69264
                     /gene="scpC"
                     /locus_tag="IT892_000247"
                     /EC_number="2.8.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionyl-CoA:succinate CoA transferase"
                     /protein_id="HAP3133500.1"
                     /translation="METQWTRMTANEAAEIIQHNDMVAFSGFTPAGSPKALPTAIARR
                     ANEQHEAKKPYQIRLLTGASISAAADDVLSDADAVSWRAPYQTSSGLRKKINQGAVSF
                     VDLHLSEVAQMVNYGFFGDIDVAVIEASALAPDGRVWLTSGIGNAPTWLLRAKKVIIE
                     LNHYHDPRVAELADIVIPGAPPRRNSVSIFHAMDRVGTRYVQIDPKKIVAVVETNLPD
                     AGNMLDKQNPMCQQIADNVVTFLLQEMAHGRIPPEFLPLQSGVGNINNAVMARLGENP
                     VIPPFMMYSEVLQESVVHLLETGKISGASASSLTISADSLRKIYDNMDYFASRIVLRP
                     QEISNNPEIIRRLGVIALNVGLEFDIYGHANSTHVAGVDLMNGIGGSGDFERNAYLSI
                     FMAPSIAKEGKISTVVPMCSHVDHSEHSVKVIITEQGIADLRGLSPLQRARTIIDNCA
                     HPMYRDYLHRYLENAPGGHIHHDLSHVFDLHRNLIATGSMLG"
     gene            complement(69261..70157)
                     /locus_tag="IT892_000248"
     CDS             complement(69261..70157)
                     /locus_tag="IT892_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417396.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3133501.1"
                     /translation="MDIFISKKMRNFILLAQTNNIARAAEKIHMTASPFGKSIAALEE
                     QIGYTLFTRKDNNISLNKAGQELYQKLFPVYQRLSAIDNEIHNSGRRSREIVIGIDNT
                     YPTIIFDQLISLGDKYEGVTAQPVEFSENGVIDNLFDRQLDFIISPQHVSARVQELEN
                     LTISELPPLRLGFLVSRRYEERQEQELLQELPWLQMRFQNRANFEAMIDANMRPCGIN
                     PTIIYRPYSFMAKISAVERGHFLTVIPHFAWRLVNPATLKYFDAPHRPMYMQEYLYSI
                     RNHRYTATMLQHIAEDRDGTSH"
     gene            complement(70324..71064)
                     /locus_tag="IT892_000249"
     CDS             complement(70324..71064)
                     /locus_tag="IT892_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress defense protein"
                     /protein_id="HAP3133502.1"
                     /translation="MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVPDI
                     ATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQIAKKDISSANLRTQPDYDYQDG
                     KSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
                     AIDNAIHQAQELANGFHRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQA
                     AIQFDDQVDVVFQLEPVDQQPAKTPAAQ"
     gene            complement(71157..71792)
                     /gene="argO"
                     /locus_tag="IT892_000250"
     CDS             complement(71157..71792)
                     /gene="argO"
                     /locus_tag="IT892_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine exporter ArgO"
                     /protein_id="HAP3133503.1"
                     /translation="MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCA
                     ISDLVLICAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGAFKTAMSSNIELASAE
                     VMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
                     FGLALLAAWLAPRLRTAKAQRIINLVVGCVMWFIALQLARDGIAHAQALFS"
     gene            complement(71931..72791)
                     /locus_tag="IT892_000251"
     CDS             complement(71931..72791)
                     /locus_tag="IT892_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small-conductance mechanosensitive channel MscS"
                     /protein_id="HAP3133504.1"
                     /translation="MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLII
                     ARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGA
                     AGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADG
                     KIIVIPNGKIIAGNIINFSREPVRRNEFIIGVAYDSDIDQVKQILTNIIQSEDRILKD
                     REMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVN
                     FKRVKEDKAA"
     gene            complement(73149..74228)
                     /gene="fbaA"
                     /locus_tag="IT892_000252"
     CDS             complement(73149..74228)
                     /gene="fbaA"
                     /locus_tag="IT892_000252"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HAP3133505.1"
                     /translation="MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSIN
                     AVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISGAHHVHQMAEHYG
                     VPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSK
                     YLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFT
                     IAASFGNVHGVYKPGNVVLTPTILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIK
                     DSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVW
                     LRAGQTSMIARLEKAFQELNAIDVL"
     gene            complement(74443..75606)
                     /gene="pgk"
                     /locus_tag="IT892_000253"
     CDS             complement(74443..75606)
                     /gene="pgk"
                     /locus_tag="IT892_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAP3133506.1"
                     /translation="MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTI
                     ELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVA
                     EGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
                     ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIA
                     NTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVND
                     VKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEA
                     FSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK"
     gene            complement(75656..76675)
                     /gene="epd"
                     /locus_tag="IT892_000254"
     CDS             complement(75656..76675)
                     /gene="epd"
                     /locus_tag="IT892_000254"
                     /EC_number="1.2.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythrose-4-phosphate dehydrogenase"
                     /protein_id="HAP3133507.1"
                     /translation="MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGM
                     AHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGV
                     YGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCI
                     IPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAG
                     ITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIV
                     DYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMA
                     TVAFR"
     gene            complement(76960..77673)
                     /locus_tag="IT892_000255"
     CDS             complement(76960..77673)
                     /locus_tag="IT892_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside/nucleotide kinase family protein"
                     /protein_id="HAP3133508.1"
                     /translation="MKIELTVNGLKIQAQYQNEEIENVHKPLLHMLAALQTVNPQRRT
                     VVFLCAPPGTGKSTLTTFWEYLAQQDPELPAIQTLPMDGFHHYNSWLDAHQLRPFKGA
                     PETFDVAKLTENLRQVVEGDCTWPQYDRQKHDPVEDALHVTAPLVIVEGNWLLLDDEK
                     WLELASFCDFSIFIHAPAQILRERLISRKIAGGLTRQVAEAFYARTDGPNVERVLMNS
                     RQANLIVEMTEEGRYHFTS"
     gene            complement(77670..78179)
                     /gene="fumE"
                     /locus_tag="IT892_000256"
     CDS             complement(77670..78179)
                     /gene="fumE"
                     /locus_tag="IT892_000256"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarase E"
                     /protein_id="HAP3133509.1"
                     /translation="MATLTEDDVLEQLDAQDNLFSFMKTAHTILLQGIRQFLPSLFVD
                     NDEEIVEYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQD
                     ETPGFADDMTWDFISNVNSITRNAMLYDALKAMKFADFSVWSEARFSGMVKTALTLAV
                     TTTLKELTP"
     gene            complement(78201..79166)
                     /gene="yggF"
                     /locus_tag="IT892_000257"
     CDS             complement(78201..79166)
                     /gene="yggF"
                     /locus_tag="IT892_000257"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HAP3133510.1"
                     /translation="MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALN
                     DVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVDIAVDPIEGTRMVAMGQSNALAV
                     MAFAPRDSLLHAPDMYMKKLVVNRLAAGAIDLSLPLTDNLRNVAKALGKPLDKLRMVT
                     LDKPRLSAAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISAC
                     AVKALGGDMQAELIDFCQAKGDYTENRQIAEQERKRCKAMGVDVNRVYSLDELVRGND
                     ILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSLH"
     gene            complement(79163..80440)
                     /locus_tag="IT892_000258"
     CDS             complement(79163..80440)
                     /locus_tag="IT892_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HAP3133511.1"
                     /translation="MKTKVAAIYGKRDVRLRVFELPEITDNELLVSVISDSVCLSTWK
                     AALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKNLTGKYKKGQRFVLQPAMGLPSG
                     YSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
                     TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQV
                     QKLLPVELAASKGIELVYVNTKGMSDPVQMLRALTGDAGFDDIFVYAAVPAVVEMADE
                     LLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQL
                     QPSFMVTHIGGLDAVPETVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKE
                     LARLVEETHGIWNEQAEKYLLAQFGVDIGEAAQ"
     gene            complement(80455..81843)
                     /locus_tag="IT892_000259"
     CDS             complement(80455..81843)
                     /locus_tag="IT892_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HAP3133512.1"
                     /translation="MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWL
                     PNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAVMGGIDTIGVIVGAEIPMFLGSM
                     IMGPLGGLVIKYVDKALEKRIPAGFEMVINNFSLGIAGMLLCLLGFEVIGPAVLIANT
                     FVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMV
                     ASNPGPGLGLLLAFTLFGKGMSKRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIA
                     GGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGVTVGTLVSFAITSLI
                     LKMEKTVETESEDEFAQSANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFR
                     KRLEKAGLAIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLD
                     TLFNQLTAEHKH"
     gene            complement(81898..82314)
                     /gene="cmtB"
                     /locus_tag="IT892_000260"
     CDS             complement(81898..82314)
                     /gene="cmtB"
                     /locus_tag="IT892_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IIA"
                     /protein_id="HAP3133513.1"
                     /translation="MRLSDYFPESSISVIHSAKDWQEAIDFSMVSLLDKNYISENYIQ
                     AIKDSTINNGPYYILAPGVAMPHARPECGALKTGMSLTLLEQGVYFPGNDEPIKLLIG
                     LSAADADSHIGAIQALSELLCEEEILEQLLTASSEK"
     gene            complement(82628..84619)
                     /gene="tkt"
                     /locus_tag="IT892_000261"
     CDS             complement(82628..84619)
                     /gene="tkt"
                     /locus_tag="IT892_000261"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAP3133514.1"
                     /translation="MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDF
                     LKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPE
                     VGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
                     GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDG
                     HDAASIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQ
                     LGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMP
                     SDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSG
                     SKAINEDAAGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAAL
                     MKQRQVMVYTHDSIGLGEDGPTHQPVEQVASLRVTPNMSTWRPCDQVESAVAWKYGVE
                     RQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGSEVELAVA
                     AYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVG
                     LNGAIVGMTTFGESAPAELLFEEFGFTVDNVVAKAKELL"
     gene            84897..85655
                     /locus_tag="IT892_000262"
     CDS             84897..85655
                     /locus_tag="IT892_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417411.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease LoiP"
                     /protein_id="HAP3133515.1"
                     /translation="MKIRALLVAMSVATVLTGCQNMDSNGLLSSGAEAFQAYSLSDAQ
                     VKALSDQACQEMDSKATIAPANSEYAKRLTTIANALGNNINGQPVNYKVYMAKDVNAF
                     AMANGCIRVYSGLMDMMTDNEVEAVIGHEMGHVALGHVKKGMQVALGTNAVRVAAASA
                     GGIVGSLSQSQLGNLGEKLVNSQFSQRQEAEADDYSYDLLRQRGISPAGLATSFEKLA
                     KLEEGRQSSMFDDHPASAERAQHIRDRMSADGIK"
     gene            complement(85861..86781)
                     /gene="speB"
                     /locus_tag="IT892_000263"
     CDS             complement(85861..86781)
                     /gene="speB"
                     /locus_tag="IT892_000263"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HAP3133516.1"
                     /translation="MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDM
                     ATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMS
                     EKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
                     FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQ
                     IVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVA
                     PAYDQSEITALAAATLALEMLYIQAAKKGE"
     gene            complement(86919..88895)
                     /gene="speA"
                     /locus_tag="IT892_000264"
     CDS             complement(86919..88895)
                     /gene="speA"
                     /locus_tag="IT892_000264"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HAP3133517.1"
                     /translation="MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWW
                     GNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRS
                     INAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
                     HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPR
                     LGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQ
                     MANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNE
                     YANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAE
                     DAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGIFSLQERAWAEQ
                     LYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVL
                     PLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
                     AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQF
                     RDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE"
     gene            complement(88904..89035)
                     /gene="yqgB"
                     /locus_tag="IT892_000265"
     CDS             complement(88904..89035)
                     /gene="yqgB"
                     /locus_tag="IT892_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response protein YqgB"
                     /protein_id="HAP3133518.1"
                     /translation="MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII"
     gene            89171..89386
                     /locus_tag="IT892_000266"
     CDS             89171..89386
                     /locus_tag="IT892_000266"
                     /inference="COORDINATES: protein motif:HMM:NF037550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133519.1"
                     /translation="MGITSAGMQSRDAECGERIFTRTVRQVKQQTTVHYFVSPPRPPV
                     KTNPQAKTLISTRLEVATRKKRRVLFI"
     gene            89690..90844
                     /gene="metK"
                     /locus_tag="IT892_000267"
     CDS             89690..90844
                     /gene="metK"
                     /locus_tag="IT892_000267"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAP3133520.1"
                     /translation="MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACET
                     YVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPD
                     INQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
                     LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLT
                     SATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFF
                     DLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK"
BASE COUNT        22544 a        23918 c        22447 g        22246 t
ORIGIN      
        1 acatagttct ctcggtgttt ttcctaaccg gctttttact tcggctgaaa agtgtgatga
       61 ggatgagtag ccatatttat gcgcaatagt tgtcatatca ctgtttcctt caatgatttc
      121 caacacggct ctggcaactc tccagccaca taattccgtt ttaactttac cacccaatgc
      181 ataactacat aaacggcgaa aatgtgaata cgatacgccg taaagttcac caagatcata
      241 gagtgaagtc tgtatgagcg attgcgataa taaatagcga accagtttat agcattctgt
      301 ttttcttaga tgctgaaaca gaatttcatt aatattatcg ctgctcagat aagtggctaa
      361 aaaccaggct tcacttgcaa ctttactgaa tagcacaact tctgatgcaa agggtaaggc
      421 atcagcaaac aacttatggt gttccctttc cacactcccc gttgattcat ctataaaagc
      481 taataattta ctcaggatat caatgcgaag tggatgataa attactttcc ctgcagttac
      541 ctcaatttgg cttcggtcaa tgagcagtaa tatatcttcc actaccatta atttttgatg
      601 gttattaccg atcgtaataa caagggttac atccttgttt tcatttcccc gtaagaacca
      661 catttcaggg tccagtaggg ttaacttctg tccttgaagc aaaacattca ttggaagtaa
      721 cagcccttct tcaatcatgt ttcatctcct tattccatat tctcattctc cataaacttg
      781 caataaaaac atgattaaaa agtgatgatt cctatttata aaataatgat tttgttatga
      841 gcgaatagct atcagctact tacagtagta agtcattctg tccatataca gaattgcaac
      901 tgttgatatg ttttacttaa acataccccg tatttcttat aacacttgtt tggtgactat
      961 tttcaataaa aatcatattt gttagttaca cattaacgca ctgcgagtgt tttgttactc
     1021 cctgcatata ttttattctc tttttcgatt ctatttttct taatcgttca tataattttc
     1081 ttgttagtcg gatttacgaa tcatgagact tatgatggat ggaatgaggc taagcggcca
     1141 ggtcaaccct gtaattactg cagcaaacaa ccgatatgtt actttttctt ccgagaagat
     1201 aaatattaag gtcgatgtca caaccagacc tatcaggtaa gctaacagta atttattgat
     1261 cacttttacc tcccttacga tttctctttg agcggtcctt ttaatccagg accgcctcat
     1321 tatgaaaact atttaattcc ctcatcattg ataaggttgg acatctcttt caacatgaga
     1381 gtcattgaag ctttcgacca atttagcgga atgatagggc ttggcgcttc atgcaaagtt
     1441 cccgacttgt ggatatagtt atagctttcg ggaagtgcca tttcaggtac actcctgcca
     1501 tttgcaccaa tcatattctc gcctgttatt tgggccaatg atctattcat aaattgcact
     1561 gagtcattca aatactcttc ttttcttgat tctttataaa caattgctgc tgattttgca
     1621 taccatgagt caaaaaacca ttctgcttct gttgatggaa tgaagctcat ttctcttttc
     1681 gcatgtgaat tttgatcggt atcagtttta atatcattga accaaaaatt tgccgactga
     1741 taattatcct tctcgtatct ttttatacca tacggacctg ctagtttttt aactattttt
     1801 agaacttgct cttttcttct ggtatttatc tttgaaagat ttgcaggata aataacatta
     1861 agtaaagccg catcggcttc tctgtaatgt ttatcttttt ccagataacc tggggattct
     1921 ccccctaaat caagctgtaa cgttattctt tcataacctt tatctatgag gtggttcaac
     1981 ctcgttgttg aaagtggttc atccagttca ttggctttag cttcgcgtag taaatcagag
     2041 ataaaaacag agtctttctt cgagagtaag ttcgacaaac gttccagtcc tgaggtcacc
     2101 agtgcaacgg aagatgtgtt taatcgggca tcttcttccc acgctccaga atcttccata
     2161 acatagaaat tggctttatc cagataagca accaacagcg caatcgatat taatcggtca
     2221 cctttttgcc aatcttcagc attaatagta ccagtgtcga ttgcttgtat aaggagatca
     2281 agataaagac ctaacgcatc attttgttta tggttccaca gctgcggctt gccttcttcc
     2341 tgcacatctg ccatcacggg ggagttgctg tcaaatcgga tatgcacagc attcatttgc
     2401 ccggaaattc catccagtcg ttttgggttg ctaatgacgt cctgcatccg cttaatctgg
     2461 tcgggcgtag acatataatc ccacagagtg agcagaacct tttttgcggc tacactattt
     2521 ccctgatctg atactaatgc catatagccc cataaactat ccctcagcca gacagcatca
     2581 tagtgggttt ctgccgctgt tttgtcatct tcgaaagtag aagcaagaat aaatgttccc
     2641 cagggtttct ccgtcaacgt taactttcgt gtattttctg ttaatgttaa caatccttga
     2701 atttcgtctt tggtatagtg gctctttatt tcatttttta atttggctga gtgaatcaga
     2761 agacgataat taggatactt atctggattt aacgataaat aacttttatc agttgctgcc
     2821 cccgtggaat taagaatgtt aaatacagat tcactcgtca cttctgcccc tgtcgcctgg
     2881 catgtgccgc atgaaaatat accagcgagc agaagagtta atgtagattt ccctttcata
     2941 aaagattcca tcaatcgttt gttaaaagcg tagataacca cttatttaac aacttgaaaa
     3001 taaggtattt tacctgggtt gttacaaatg gattgcattg cgtaaacgct tttatttaca
     3061 aaaaaatggg gaagtattac ggcgattgcg aaaagtctga agcgattgaa ttaagataat
     3121 atagaaaatc agatacaaca aaaatggcag gttgatgagg tgaagataaa ttggagcggg
     3181 cgaagggaat cgaaccctcg tatagagctt gggaagctct cgttctacca ttgaactacg
     3241 cccgcttcga gatgcgtaag gcattataaa ccttacgctc tccttagcaa gtgccgcgct
     3301 gctgactgct gattaattcg ccatcagcat tttggcttgc tgccctgagg cggcaagtaa
     3361 cgcagcggat caattgccgt agcacggtaa cgaatctgga aatgcaggcg aaccgatgcc
     3421 gcatcagtgc tccccatagt ggcgattttt tgcccagcct tcacgctttg cccattattt
     3481 accagcatcg tgtcattatg ggcgtaagcc gtaatgtaat cttcactgtg tttaatcatg
     3541 atgagattac cgtagccacg cagctggttg cccacataca ccacctttcc tgcacccgcg
     3601 gcgtaaatag gtgtaccccg tggagctgag atatcaatcc ctttattgcc gccatcagct
     3661 gtcgaatacg gcatgataac tttccctgtc gttggccata accaacaacg ttgccctact
     3721 ggcggccagg aagatttcgg tactgctgat gacggtgtaa ccgatgcggt tttggtcgtt
     3781 gatttggcgg ttgatttacg tgtactgcta cttttcgccc cacccagttt tagtttctga
     3841 ccaacttcaa tggtgtaagg gggggaaatg ccgttcagtc gcgccagctc ttttacgctg
     3901 gttcccgtgg tgcgcgaaat acgatatagc gtatcccccc gtttcacggt gtaaacggag
     3961 ccggaatacg ttcctgtatc ggatgacttg ctacccgagc agcccgccaa aagcagtcca
     4021 accgataaca acatcacgat acccagagat tttttattca ggcgtcccgc actcaaaatc
     4081 tttcctcgct taaaaaacaa gacgccatat catagcagcc agcctctgga tacccaatct
     4141 cttgcttctc gaaaaacgcg gtaatagaga aagaggttaa tttcatttgg caaagggaag
     4201 tatcatcagc aaaatattcg ctgcagaggt atcgaatttc ctgacttttt taccctattt
     4261 cccatcctga tgcgtaataa tcctgattta tcacattgat tttatcgcca ctcatattga
     4321 tacgtatcac tgcccctatt cagagtcctg tttcgtatca tatctgtgtt tttttaacgt
     4381 catcacactt ccttcctccc ctaacgctta tcgtcgtttc tggcgtaaat cttgcctgct
     4441 tagactaaat ctttgccata agaaccaaat gttcaaatcg aggggatttc tatggaagcg
     4501 cgggaagcaa ccgctacggg tgaatcttgc atgcgcgtcg atgccattgc taaggtcacc
     4561 gggcgggcac gatatactga cgattatgtt atggcgggca tgtgttacgc gaaatatgta
     4621 cgtagcccta tcgcacatgg ttatgccgta agtattaatg atgaacaagc cagaagttta
     4681 ccaggcgtac tggcgatttt tacctgggaa gatgtacctg atatcccatt cgctacagct
     4741 gggcatgcct ggacacttga cgaaaacaag cgcgataccg ccgatcgcgc actgctaact
     4801 cgccatgttc gtcaccatgg agacgccgtt gccatcgtcg tggcccgtga tgaactcacg
     4861 gcagaaaaag cggcgcaatt ggtcagcatt gagtggcaag aattacccgt tatcaccacc
     4921 ccagaagcgg cgctggctga tgacgctgaa ccaatccata acggcggcaa tttactaaaa
     4981 caaagcacga tgtcgacggg caatgtccaa caaacaatcg atgccgccga ctaccaggta
     5041 caggggcact atcagacgcc ggtcattcaa cattgtcaca tggaaagcgt gacatcgctg
     5101 gcatggatgg aggatgactc gcgaattacc atcgtttcca gcacccagat cccgcacatt
     5161 gttcgccgtg tggttggtca ggcgctgaat attccctggt catgcgtacg agtcatcaaa
     5221 ccgtttgtcg gtggcggttt tggtaataaa caggatgtac tggaagagcc aatggcggca
     5281 ttcctgacca gcaagcttgg cggcattccg gtgaaagttt cccttagtcg tgaagaatgt
     5341 ttcctcgcaa cccgtacccg ccacgctttc actattgacg ggcaaatggg cgtgaaccgc
     5401 gacggaacat tgaaaggtta tagtctggat gttctgtcta acaccggcgc ttatgcatct
     5461 cacgggcact ccatcgcttc tgcgggaggg aataaagtcg cttaccttta tcctcgttgt
     5521 gcctacgctt acagttcaaa gacctgctat accaacctcc cctcggctgg tgcgatgcgt
     5581 ggttatggcg cgccacaagt cgtatttgcc gttgagtcta tgcttgatga cgccgcgaca
     5641 gcgttaggta ttgatcctgt tgaaattcgt ttacgcaacg ccgcccgcga aggagatgct
     5701 aatccgctca caggaaaacg tatttacagc gcagggttgc cggagtgtct tgaaaaaggc
     5761 cggaaaatct ttgaatggga aaaacgccgt gcagagtgcc agaaccagca aggcaattta
     5821 cgccgcggcg ttggcgtcgc ctgttttagc tacacctcta acacctggcc tgtcggcgta
     5881 gaaatagcag gcgcgcgcct gttgatgaat caggatggaa ccatcaacgt gcaaagcggc
     5941 gcgacagaaa tcggtcaggg tgccgacact gtcttctcgc aaatggtggc agaaaccgtg
     6001 ggggttccgg tcagcgacgt tcgcgttatt tcaacccaag ataccgacat tacgccgttc
     6061 gatcccggtg catttgcctc acgccagagc tatgttgccg cgcctgcgct gcgcagtgcg
     6121 gcactgttat taaaggagaa aatcatcgct cacgccgctg tcatgctaca tcagtcagcg
     6181 atgaatctta ccttgataaa aggccatatc gtgctggttg aacgaccgga agagccgtta
     6241 atgtcgttaa aagatttggc gatggatgcc ttctaccacc ctgaacgcgg cgggcagctc
     6301 tctgccgaaa gctccatcaa aaccaccact aacccaccag cgtttggctg tacctttgtt
     6361 gatctgacga tcgatattgc gctgtgcaaa gtcaccatca accgcatcct caacgttcat
     6421 gattcgggcc atattcttaa tccgctactg gcagaaggtc aggtacacgg cggaatggga
     6481 atgggcattg gctgggcgct atttgaagag atgatcattg atgcgaaaag cggcgtggtc
     6541 cgtaacccca acctgctgga ttacaaaatg cccaccatgc cggatctgcc acaactggaa
     6601 agcgcgttcg tcgaaatcaa tgagccgcaa tccgcatacg gacataagtc actgggtgag
     6661 ccaccaataa ttcctgttgc cgctgctatt cgtaacgcgg tgaagatggc taccggtgtt
     6721 gcaatcaata cactgccgct gacgccaaaa cggttatatg aagagttcca tctggcagga
     6781 ttgatttgag gataacatca tgtttgattt tgcttcttac catcgcgcag caacccttgc
     6841 cgatgccatc aacttgctga ctgacaaccc gcaggccaaa ttgctcgccg gtggcactga
     6901 cgtactgatt cagctccacc atcacaatga ccgttatcgc catattgttg atattcacaa
     6961 tctggcggag ctgcggggaa ttacgctggc ggaagatggc tcactacgta tcggctctgc
     7021 aacgacattt acccagctca ttgaagatcc tgtaactcaa cgtcatctcc cggcgttatg
     7081 tgctgcggcc tcgtccattg ctggaccaca gatccgtaat gtcgctacct acggtggaaa
     7141 tatttgcaac ggtgccacca gcgcagattc tgccacgcca acgctgattt atgacgcgaa
     7201 actggagatc cactccccgc gcggtgttcg tttcgtcccg attaatggct ttcacaccgg
     7261 accgggcaaa gtgtctcttg agcatgacga aatccttgtc gcctttcact ttccgcccca
     7321 gccgaaagaa cacgcgggca gcgcgcattt taaatatgcc atgcgcgacg caatggatat
     7381 ttcaacgatt ggctgcgccg cacattgccg actggataac ggcaatttca gcgaattacg
     7441 tctggcattt ggtgttgccg cgccaacgcc gattcgctgc caacatgccg aacagactgc
     7501 acaaaatgcg ccattaaacc tgcaaacgct ggaagctatc agcgaatctg tcctgcaaga
     7561 tgtcgccccg cgttcttcat ggcgggccag taaagagttt cgtctgcatc tcatccagac
     7621 gatgaccaaa aaagtgatta gcgaagccgt cgccgcggcg gggggaaaat tgcaatgaat
     7681 cacagcgaaa caattaccat cgaatgcacc attaacggga tgccttttca gcttcacgcc
     7741 gcaccaggca tgccgctctc ggaattactc cgcgatcaag gactgttaag tgtcaaacaa
     7801 gggtgctgcg tgggtgaatg tggtgcctgt acggtgctgg tcgacggcac agcaatagac
     7861 agttgcttat accttgccgc ctgggctgaa ggaaaagaga tccgcacgct ggaaggtgaa
     7921 gcgaaaggcg gaaaactttc tcatgttcag caggcttatg cgaaatccgg cgcggtgcag
     7981 tgcgggtttt gtacgcctgg cctgattatg gctaccacgg caatgctggc aaagccgcgc
     8041 gagaagccat taaccattac ggaaattcgt cgcggtctgg cgggaaatct ttgtcgctgc
     8101 acggggtatc agatgattgt aaatacagtt ctggattgcg agaaaacgaa gtaaaaggat
     8161 atccggcctg aattcaggcc ggattcactg aggttatgtg tttaacaact catatttctt
     8221 aatcttgcga tagagcgtag caataccgat gcccagttca tcagcaactt gcttcttgct
     8281 gttatgacgt gaaagcgcct cgcggatcat ttgcttttcc atctcctcca gcgccgtgcc
     8341 gcccgcatca tcgagtgcca ggtgcgcctc gctgacctct gttacatcac tttgttccgt
     8401 tgtgccatta ttcagcagat ttggcggcaa tagcgtgcta tcgataactt cacctgaagg
     8461 aacaacgtta accagatatt ccatcaaatt gcttaactcg cgcaggtttc cgggccaacg
     8521 atgcttacgc aatatttcga cgacatcagg agcaatgcca ggataaaccg atcccagacg
     8581 acgggtatgc agatgtaaaa agtaatgcac cagtagttca atatcttcct ggcgttcacg
     8641 cagcggtgga agagttatcg ggataacatt aagtcggtag aagagatctt cgcggaattt
     8701 accttcggca atgaactggg ccaaattctg gttagttgca gaaatgatgc gaatgtcgac
     8761 ttgtattggg ctactggcac caatcggcag aatttcacgt gcctcaatag cgcgcagtaa
     8821 tttagcctgc aacattaatg gcatatcacc tatttcatcg agaaacagcg tgcccgtatt
     8881 cgccgcctga atcaaccctg ttttaccgtt ggcagaagcg ccagtaaatg cgcctttaac
     8941 ataaccgaac agttcgctct ccagaagctg ctccggaatc gcggcacagt tgatagcaat
     9001 aaaaggttta ttccgtcttc cgctcaactt atggattgca cgggcgacga cttctttacc
     9061 cgtgccgctt tcaccaacca ccataacgct ggatgggctg ggtgcaatac ggctaatgag
     9121 tcgttttaat tgccgcataa cacggcactc gccaaccaat tgttcaatat gcggttcatc
     9181 aggtgcattt gctacagaaa aactggtatg cgattggtga aacgccatta aaaataattg
     9241 tcggccctga atgttatgca attgaccaat gattaactca cttttatcgt cccacgaaac
     9301 aatatgctgc atatgtccat gggtaaaatt actctcaaat gttaatggtc tgaaacggat
     9361 aggtttccca ataatattat tttgcacaac accgagtgtt tttaaggctg tctgattaac
     9421 aaactgaacc cgattatcgt catcaacaac taatacaccc tgatccatat tatcgatcat
     9481 ggtcgcgaat attttactga tgttatctcc tggtccctga tcctccagaa gtttcgaaac
     9541 aaaaatggtg gatatatggc gaacgtaatc agaaaattcg cgtaaattat cactaatatg
     9601 ctcttgttgc tcgtgggtaa cggcaatcaa acttatcacc ccaacacaac gatcctgtaa
     9661 aatgacaggc gtacccagaa atgctttttc gcggcaattt tctttactat cgcaaccttc
     9721 acaaagggga tcgaagcgag actgtgtcac aactttttca gttttcgttt ccaggacgtg
     9781 gcggagcagg cgtgagttgc cgctcaactg gcgaccaaga aacttcccat acgcgcccgt
     9841 tccggcgacg cgacacaagt tttcatcaac gatctcaacc tcaagctgca aaacgctggc
     9901 aagcattctg gcaaaacgct gaattgtcgg ttgaatttgc atcaatactg actgcgtagt
     9961 agcaagctcc atagctttac cttccagact tacttaaaag tcgatcattg aagacgttga
    10021 tggttcatag atcatgatga tattaactca ggcgaaattg gctttgataa aaacataaga
    10081 tttttatcac tttctaatga aattatggaa gagatatcac atttctatat caatatgaga
    10141 attacggcgg tgagtttatc aaactgacga gggataacct gcccctttat cttatttctg
    10201 atacttagca gcaaataaat aacgcgataa aaaaagccaa acgttttcgt attttacaaa
    10261 caaccagaag ctggcatcaa tttgtgatca accccacaca ttacccgtca aattagtctt
    10321 ttgcagccgc ttggataatt ctggcacagt tattgttagt cccaggtata gctgtgaaaa
    10381 caccaatcac tttggcaagt cacagtgaaa taaacctctt tgcctgtcat tccactaccg
    10441 ggactttatg atgaaaactg ttaatgagct gattaaggat atcaattcgc tgacctctca
    10501 ccttcacgag aaagattttt tgttaacgtg ggaacagacg ccagatgaac tgaaacaagt
    10561 actggacgtt gccgcagcat taaaagcact gcgtgctgaa aacatctcaa ccaaagtctt
    10621 taatagtgga ttaggtattt ccgtattccg cgacaactcc acccgtaccc gcttctctta
    10681 tgcttccgcg cttaacctgc tcggccttgc acagcaagat ctcgacgaag gcaaatcaca
    10741 aatcgctcac ggcgaaaccg tgcgtgaaac cgccaatatg atctccttct gcgccgatgc
    10801 catcggtatt cgtgacgata tgtatctggg cgcaggcaac gcctatatgc gtgaagttgg
    10861 cgctgcactt gatgacggtt acaagcaggg tgtgctgccg caacgtccgg ctttagtgaa
    10921 cctgcaatgc gatattgacc acccgactca gtcaatggct gacctggcat ggttacgtga
    10981 acactttggt tcactggaaa acctgaaagg taaaaaaatc gccatgacct gggcctactc
    11041 cccaagctat ggcaaaccgc tctctgtacc acaaggcatc atcggtctga tgactcgctt
    11101 cggtatggat gtcaccctgg cccatccgga aggctacgac ctgatcccgg atgtggttga
    11161 agtggcgaaa aacaatgcta aagcatccgg tggtagcttc cgtcaggtca ccagcatgga
    11221 agaagccttc aaagacgcag acatcgttta tccgaagtca tgggcacctt acaaagtgat
    11281 ggaagagcgt actgaattgc tgcgtgcgaa cgaccacgaa ggcttaaaag cactggaaaa
    11341 acagtgtctg gcacagaacg cgcaacacaa agactggcat tgtactgaag agatgatgga
    11401 actgacccgt gatggcgaag ccctgtacat gcactgcctt ccagctgata tcagcggcgt
    11461 atcctgtaaa gaaggtgaag tgactgaagg cgtattcgaa aaataccgta tcgcaaccta
    11521 caaagaagcc agctggaagc cttatatcat cgccgcgatg atcctgtccc gtaaatacgc
    11581 caaaccaggt gcactgctcg agcaactgct gaaagaagcg caagaacgcg tgaaataacc
    11641 cctcgggccg atcagctggt cggccctcta tttccagagg ccaaaaggat aggatatgtc
    11701 cgttttctca ttgaagattg atatcgccga taacaaattt ttcaacggcg aaacatcacc
    11761 gctcttttcg caaagccagg ccaaactggc gcgccagttc caccagaaaa ttgctggtta
    11821 tcgcccaaca ccgctttgtg cgctggacga tctcgcaaac ctttttggtg tgaagaaaat
    11881 tctcgtcaaa gacgaatcaa aacgattcgg tctgaacgcc ttcaaaatgc tcggcggtgc
    11941 atacgccatc gctcaattat tgtgcgaaaa atatcatctt gatatcgaaa cgctgtcatt
    12001 tgagcacctg aaaaatgcca tcggcgaaaa aatgactttc gcgaccacca ccgacggcaa
    12061 ccacgggcgc ggtgtggcgt gggcagcaca gcaactcgga cagaatgcgg tgatttacat
    12121 gccgaaaggt tctgctcagg aacgcgttga cgccattctg aacctcggtg ccgagtgcat
    12181 cgtcacggat atgaactatg acgataccgt tcgcctgacc atgcaacacg cgcagcagca
    12241 cggctgggaa gtggtacagg acacagcatg ggaaggttac accaaaatcc caacctggat
    12301 catgcaaggc tacgcaacac tggcagatga agccgtcgag caaatgcgtg aaatgggcgt
    12361 aaccccgaca cacgttctgc tgcaagccgg tgtcggtgca atggccggtg gtgtgctggg
    12421 ttatctggtc gacgtctaca gcccgcaaaa tctgcacagc attattgttg aacctgacaa
    12481 agctgactgt atttatcgct ccggcgtcaa aggcgacatc gtcaacgttg gcggtgatat
    12541 ggccaccatc atggcgggcc tggcctgcgg cgaacctaac ccgctgggct gggaaatcct
    12601 acgtaactgc gccacccaat tcatctcctg ccaggacagc gttgccgcat taggtatgcg
    12661 tgtgctgggt aatccgtacg gcaatgaccc gcgcatcatc tccggtgaat ccggcgctgt
    12721 cggtttgggc gttctcgcag cggttcatta tcacccgcaa cgtcaaagcc tgatggaaaa
    12781 actggcgctg aacaaagatg ccgtagtgct ggttatcagc actgaaggcg acaccgacgt
    12841 gaagcactac cgcgaagttg tctgggaagg caaacacgct gtagcacctt aatcacccta
    12901 ttggaactgc tccctgcaaa acggggagta aaaaatctgg agaaaaataa tggctaagaa
    12961 tattccattc aaactgattc ttgaaaaagc aaaagattac caggcggaca tgactcgctt
    13021 cctgcgcgac atggttgcta ttcccagtga aagctgcgac gaaaaacgcg tagtacatcg
    13081 tattaaagaa gagatggaaa aagtcggctt cgataaagtt gaaatcgacc cgatgggcaa
    13141 cgttctcggt tatatcggcc acggcccgcg tctggtggca atggacgctc atatcgatac
    13201 cgtcggcatt ggcaacatca aaaactggga cttcgatccg tacgaaggca tggaaactga
    13261 tgagctgatc ggtggtcgcg gtacttccga ccaggaaggc ggcatggcat ctatggttta
    13321 tgccggtaaa atcattaaag acctcggtct ggaagatgaa tataccctgc tggttaccgg
    13381 tactgtgcag gaagaagact gcgacggcct gtgctggcag tacattattg aacaatccgg
    13441 cattcgcccg gaatttgtgg tcagtaccga accaaccgac tgccaggtat accgtggtca
    13501 gcgcggtcgt atggaaattc gtattgatgt tcagggtgtt agctgccacg gttctgcacc
    13561 agaacgcggt gacaacgcca ttttcaaaat gggtccgatt cttggcgaat tacaagaact
    13621 ctcccaacgt ctgggttatg acgaattcct cggcaaaggc accctcaccg tttctgaaat
    13681 cttcttcaca tccccaagcc gttgcgctgt agcagatagc tgcgccgtct ctattgaccg
    13741 ccgtctgacc tggggcgaaa cctgggaagg cgcgctggac gaaatccgcg ccctgcctgc
    13801 agtacagaaa gctaacgcgg ttgtttctat gtacaactac gaccgtccgt cctggactgg
    13861 cctggtttac ccaaccgaat gctacttccc gacctggaaa gtggaagaag atcacttcac
    13921 cgttaaagca ctggtgaatg cctacgaagg tctgtttggc aaagcgccgg ttgttgataa
    13981 gtggaccttc tcaactaacg gcgtatctat catgggccgt cacggcattc cggtgatcgg
    14041 ctttggcccg ggtaaagaac ctgaagcgca tgcacctaac gaaaaaacct ggaaatctca
    14101 cctggtgacc tgtgccgcga tgtacgctgc aatcccgtta agctggctgg caaccgaata
    14161 attactcttc acttattccc ctccggttcg ccggagggtt tttggagttt gctatgcgcg
    14221 tattgatcaa aaacggcact gtcgttaacg cagatggaca agccaaacag gatttgctga
    14281 ttgaaagcgg gattgttcgc cagttgggca acaatatttc gccacagctc ccgtatgaag
    14341 aaattgatgc cactggctgt tacgttttcc ctggcggcgt ggatgtccat acgcatttca
    14401 atattgatgt cggcatcgcg cgcagttgtg atgatttttt taccggtacc cgcgcagctg
    14461 cgtgtggcgg tacaacaacc attattgacc atatgggatt tggcccgaat ggctgccggt
    14521 tacgccatca actggaggtt tatcgtggtt atgccgccca taaggcggtc atcgactaca
    14581 gctttcacgg tgtgatccag cacattaatc acgccatcct cgacgaaatc ccgatgatgg
    14641 tcgaggaagg gctgagcagt tttaaactct atttaaccta tcaatacaaa ctcaacgatg
    14701 atgaagtgtt gcaggcatta cgccgcttgc atgaatccgg cgcgctgacc accgtgcacc
    14761 cggaaaatga tgcggctatc gccagcaagc gggcggagtt tattgccgca gggttaaccg
    14821 cgccgcgcta tcacgccttg agtcgccctc tggaatgcga agcggaagcc atcgcccgca
    14881 tgattaacct ggcacaaatt gccggtaacg ccccgctcta tatcgtgcac ctgtctaacg
    14941 gcttaggtct ggattatctg cgtcttgccc gtgcgaatca ccagccagtc tgggttgaaa
    15001 cctgcccaca atatctcctg ttggacgaac gcagttacga tacagaagat ggcatgaagt
    15061 tcattcttag cccaccgctg cgtaacgtac gcgagcagga caaactgtgg tgtggcatca
    15121 gcgatggtgc gattgacgtg gtggcaaccg atcactgcac cttctcgatg gctcaacgcc
    15181 tgcaaatttc taaaggcgat ttcagtcgct gcccaaatgg cttacccggt gtggaaaacc
    15241 gcatgcagtt actgttttcc agtggcgtga tgacgggacg tataacaccg gaacgctttg
    15301 ttgaattaac cagcgcaatg cccgccaggc tgtttggcct gtggccgcaa aaaggattat
    15361 tagcgcccgg ttccgatggc gacgtggtga ttatcgaccc acgtcagagc caacaaattc
    15421 agcatcgcca tctccacgac aacgccgact actcgccatg ggagggtttt acctgtcagg
    15481 gcgcgattgt cagaacctta tcccgtggtg aaacgatttt ctgtgacggc acctttacag
    15541 gcaaagccgg gcgaggtcga ttcctgcgac gcaaaccgtt tgtccctccc gtgctctaac
    15601 cactgccagg gatctataca caatcaagaa tgatgagtga ggaaaaatga gtaagaaaat
    15661 tgttctcgcc ctgggcggga atgcgctggg cgatgacctg gccggacaaa tgaaagcggt
    15721 aaaaattact tctcaggcaa ttgttgattt aattgcccag ggacatgagg tcatcgtcac
    15781 tcatggtaac gggccgcagg tgggcatgat taaccaggcc tttgaagctg ccgcaaaaac
    15841 tgaagcgcac tcgccaatgc tgccgatgtc tgtctgtgtt gccttaagcc agggttatat
    15901 tggttacgat ctacaaaatg ccttaagaga agaactgctt tctcgtggca ttaataaacc
    15961 tgtagcaacg ctggttaccc aggtcgaagt cgacgctaac gatccggcat tcctcaaccc
    16021 gaccaagccg atcggttcgt tctttaccga gcaagaagca gagcaactga caaaacaggg
    16081 ttacactctg aaagaagatg ctggtcgcgg ctatcgccgt gttgttgcct cgccaaaacc
    16141 ggttgatatc attgaaaaag aaacggttaa agcgttggta gatgcaggcc aggtggtgat
    16201 caccgttggc ggtggtggta tccctgttat tcgtgaaggt aaccacctgc gtggtgccag
    16261 tgcggttatc gataaagact gggccagcgc ccgtttagca gaaatgattg atgccgatat
    16321 gctgatcatt ctgactgcgg tagaaaaagt ggccattaac ttcggtaaag agaatgaaca
    16381 gtggctcgat cgcctgtcat taagtgatgc tgaacgcttt atcgaagaag gtcattttgc
    16441 gaaaggttct atgctgccta aagtggaagc tgccgcctcg tttgctcgct ctcgcgcagg
    16501 tcgtgaagca ctgattaccg tattgagcaa agcgaaagaa gggattgaag gcaaaaccgg
    16561 aacggtgatt tgtcagtaat ttaaaggccg ggtgggtaaa taccatccgg ccattttcat
    16621 ttaagccact tccagcactt ctttcgtcgc tttaacaccc tgatgcatca acatcattaa
    16681 cgcctcaagt acgccgccgc caatcgcccg ggctttatca gaaacgctgg tgaaatcagc
    16741 cgtttcacca cgaggatcga tatcaccaat tttaaaacca ccgaccactg ctagtccgtc
    16801 gttcaacaag ccacgcacca tccccgtcaa cggtgcttta atttcatgct caccaatcca
    16861 ggcaatcaca tcgccctctt tcaccagatc gcctaatttc acgttggatc gcataatgcc
    16921 tgcagcagga gcacggatca cccgtcgggt ggtatgcccc ataatattgc caggaacacc
    16981 ggtattctcc tgcgcacaac cagagtaaat cacctgaccg agccagtgcc cgcgatttgt
    17041 ttcaattacc gcatgacaat ccttccctgc aataaagccc ggcccaagcg cgattgttac
    17101 tggtgccata tctgcccgcg tccccaaatt ctgtttcgcc agaatagcgt ccaccacgca
    17161 aagcggtttc agttcatcaa gcaatgaaca ggcgggatct accatcacag ggatgaatcc
    17221 gcgttcggta agtttcatcg cttccgcaga gctggttgcc aggcgggcag tgacgccttc
    17281 gaccgtcatt tcgccatcga acacggcctg ggcaaacgcc acggtacaac gaatcactgt
    17341 cggtttttcc acttccagca tgatcacttt aaaacccgca tgatacagac gtagcgccac
    17401 accactggcg atatcccccg caccgcgaat caccaccagc tggtgtccgg aaggatgaga
    17461 aggtttcatc atcagcccac ccggcgcgtt atttttcacc tgtaatattt ctgccagcac
    17521 gctgatggcg atctcctgcg gcgtttccgc acctatgttg taaccaacag gcgcatgtaa
    17581 acgggcaata tgttcttcag ccacgccttt ctcacgcaat tgacgcagga aaagctgaac
    17641 cttgcgacga cttgccagca accccaacca tgcaatgggc tgttcaatga gtttgtcgag
    17701 ggcttcacga tcctgattat tcgtggcaat caggacaaaa ttatcagggc gaatatccag
    17761 tgcttccact gccgcaccaa acgactcagc atggagaagc gtggttgatg gtgggaataa
    17821 ttcaggatta aggctttcgc gataaatatc ggcaacggca atatcaaatc ctaatagcgc
    17881 cgcactctgg gctatcgccc ggttgacatg ccccgcgcca atcaacacca gacgtggacg
    17941 cataccatgg acgctgataa atactgacat tgcacctcca caatctgacc cgacagcatc
    18001 cgcaccgtta cgagccatac gtccatggaa taatcgcggc ttacgttcct gcaatgcctg
    18061 aagcgactct tcaatcacct tccgctcaac cattcctcca ccaattgtac cgacgataga
    18121 accatcggcg cgcactaaca tttgtgcaga atggcgggga gtagagcctc ggctatctac
    18181 aatttgcgcc atcgcaaacg gacaattttg ctcttcgagt tttgcagcct ctgtgaaaat
    18241 attcatacca acctcaatgg atatcctttc agtaacccgg aatacccggg ccgctaattc
    18301 acaaatctgc gcgcgattgc aggatgttct tgtatatcgc ccagccagat tgcctctacg
    18361 ttgtgttgtt gcagcggttg aaggagctcg ctttgcgcaa tcgcattctc acattgagaa
    18421 aaacggttaa tgaaccagac tcgccgacaa ccttgcggta cgtttttaaa cgcgccctga
    18481 gggtggcgaa ccagcgcaac gagatcgctc agttgcaagg gtgcatcagg tgttaaccca
    18541 gtaatatcag caaactgcga ccagcgatgg acattttctg tgctcacttt tgcacccaaa
    18601 atatgtcctc ccatcacagc aatcacgcag caactgcttt taggtatgca aggttcgtgc
    18661 tcatcaggcg cttttaacgg cattccacgc gagccatctg cctcaatgag aattacgtca
    18721 cactctggtc gttgcaccag tgcatcaatc gcttctggcg taaatccctg cacctttccc
    18781 tggttcgctt tccagctgtg aaaacaaaat gaaatggggg atgtaagaga cgcatgagga
    18841 agcatggcgg gatcacgaca gaaaaccacg ggccagtgag acgttggcat aaacatatgt
    18901 gtcgtcgtag tgattaacac acgcctgccg ctagcctgga gcagttctgc cagccaaaaa
    18961 agcaagctgg ttttcccccc agccccaaca acagaaatca cagtgggacg tttctgcgcg
    19021 cctaaatcaa tgaataatgc cgatgggtca actatacttt tcacgagtct ttatgacctc
    19081 tctgggataa attatcccca acttaatcca tcaggaagta acgcaattat caggcgttat
    19141 tagcccctat aaataatgga accactatgt cagccatcga ctgtataatt accgctgccg
    19201 gattatcatc aagaatgggg caatggaaaa tgatgttacc ctggcaacag ggaacaattc
    19261 ttgatacaag tatcaaaaat gcgttgcagt tttgtagccg aattatttta gtcaccggct
    19321 atcgtggtaa tgaactgcac gaacgttatg cgaaccagag caatatcact attattcaca
    19381 acccagatta tgcgcagggt ttactcacat cagtaaaggc cgcagtaccc gcggtaaaaa
    19441 cagaatattg ttttctcacc cacggtgaca tgcctaccct caccatcgat atttttagaa
    19501 aaatctggtc gttacgaaat gatggcgcaa tactgccact ccataatggc attcccggcc
    19561 atccgatttt agtgtcaaag ccatgcctga tgcaggcaat ccagcgtccc aatatcacca
    19621 atatgcgtca ggcactcctt atgggagatc attattccgt cgaaatagaa aatgcagaaa
    19681 taattttaga tattgatact ccggacgact ttattacagc gcaaaaaagg tatactaaaa
    19741 tttagaaaat gtagttaaac gattgcgttc aaatatttaa tccctccagc actctttatc
    19801 ataatgataa ggaatcactg attttgagaa aagagaaaaa gtgataaatg ggctggcaat
    19861 aataattttc aggagtgatt ttaattctca tttggcacct gtgagttcat tcacaaaaag
    19921 ctcctaagtt tcgagccgcc tcacattttt ttatatttcc cgccaaacct ggcaagagtg
    19981 gtgcgattgt tgctctatcc ccctaaacca ccggatttct caacaccggt cactcaatga
    20041 tatctgtata agctaaggag agggttatgg gggatattat gcgtcccatt ccgtttgagg
    20101 aacttttgac gcgcatattt gatgaatacc aacaacaacg ctcaatcttt ggtattcccg
    20161 agcaacagtt ttactcaccc gtaaaaggta aaactgttag cgtcttcggt gaaacctgtg
    20221 ccactcccgt cggccctgcc gctggcccgc acacgcagct cgcgcaaaat attgtcactt
    20281 cctggctgac tggcgggcgc ttcatcgaac taaaaaccgt ccaaattctt gaccgtctgg
    20341 agctggaaaa gccctgtatc gatgccgaag acgagtgctt taacaccgaa tggtctaccg
    20401 aatttaccct gcttaaagcc tgggatgaat acctcaaagc ctggtttgcc ctgcaccttc
    20461 tcgaagcgat gttccagcct tctgattccg gtaaatcgtt catctttaat atgagcgtcg
    20521 gttataacct cgaaggtatt aagcaaccgc cgatgcaaca gttcatcgac aatatgatgg
    20581 atgcatctga ccatccgaaa ttcgctcaat atcgcgatac gctgaataaa ttactccagg
    20641 atgacgcatt tttagcccgc cacggattgc aggaaaaacg cgaatgcctg caggccttac
    20701 cggcacgcat ccccaccagc atggtacaag gcgttaccct ctccaccatg cacggctgtc
    20761 ctccgcatga aatcgaagcc atttgccgct acatgctgga agaaaaaggg ctcaatacct
    20821 ttgtgaaact caacccgacc ttactggggt acgcgcgtgt tcgtgagatc ctcgatgtct
    20881 gcggtttcgg ttacataggc ttaaaagaag agtcatttga tcacgacctc aagctgacgc
    20941 aagcgttgga aatgctggaa cgcctgatgg tactggcaaa agaaaaatca ctcggctttg
    21001 gcgtaaaact gactaacact ctcggcacca tcaacaataa aggcgcactg cctggtgaag
    21061 agatgtatat gtcaggccgt gcgctgttcc cgctctccat caatgttgca gcagttctct
    21121 ctcgcgcctt tgacggcaaa ctgcccattt cttattccgg tggtgccagt cagctgacta
    21181 tccgcgatat ttttgatact ggtattcgcc ctattactat ggcaaccgac ctgctgaaac
    21241 ctggcggcta tctgcgctta agtgcctgca tgcgcgagct ggaaggctcc gacgcctggg
    21301 ggcttgacca tgttgacgtc gaacgcctga acaaactggc agcagacgcg ttaaccatgg
    21361 aatacactca gaaacactgg aagccagaag agcgtattga agtggcagaa gacctgccgc
    21421 tgaccgactg ctacgttgca ccgtgcgtta ctgcttgcgc cattaaacag gatattccgg
    21481 aatacatccg tctgcttggc gaacaccgct atgccgacgc actggaactc atctaccaac
    21541 gcaacgccct gcccgccatt accggtcata tttgcgatca ccagtgccaa tacaactgta
    21601 cccgcctgga ttacgacagt gcgctgaata tccgcgaact gaaaaaagtc gcgctggaaa
    21661 aaggttggga tgaatataag caacgctggc acaaaccagc cggttctggt tcacgccatc
    21721 cggttgccgt gattggtgca ggtccggcgg gtctggcagc aggttacttc cttgccagag
    21781 cgggccatcc ggttacgctg tttgaacgcg aagccaatgc gggcggcgtg gtgaaaaata
    21841 tcattcctca gttccgtatt cctgcagagt taattcagca cgatatcgat tttgttgccg
    21901 ctcacggcgt gaaatttgag tatggctgct cacccgattt gaccgttgaa cagttaaaaa
    21961 atcagggctt ccactatgtt ctgattgcca ccggcactga taaaaatagc ggtgtgaaac
    22021 tggcgggcga caaccaaaat gtctggaaat cactcccctt cctgcgtgaa tacaacaagg
    22081 gcacagcgct caagctgggc aaacatgtgg tcgttgtcgg ggcgggtaac acggcaatgg
    22141 actgcgctcg tgcggcgtta cgcgttccag gcgtagaaaa agcaacggtc gtttaccgtc
    22201 gttcactgca agagatgcca gcatggcgcg aagagtatga agaagcgttg cacgacggcg
    22261 tggagttccg tttcctgaat aatccggaac gtttcgatgc tgatggcacc ttaaccttgc
    22321 gcgttatgtc gcttggcgaa cctgatgaga aaggtcgtcg ccgtccggtt gaaaccaacg
    22381 aaacagtaac actgcatgta gacagcctga tcaccgccat tggtgaacag caggatactg
    22441 aagccctgaa tgcgatgggc gtgccgctgg acaaaaacgg ctggccagac gtcgaccata
    22501 atggcgaaac tcgtctgact gacgtcttta tgatcggcga cgtacagcgc ggaccatcct
    22561 ccattgtcgc tgctgtcgga accgcgcgtc gggcgaccga tgtcatcctt agtcgggaaa
    22621 acatccgttc ccaccagaac gataaatact ggaacaacgt caatccggcg gaaatctatc
    22681 aacgcaaagg cgatatctct atcaccctgg tggatagcga cgatcgtgac gcgtttgtcg
    22741 cccaggaagc cgcacgctgc cttgaatgta actacgtttg cagcaagtgt gtggatgtct
    22801 gcccgaaccg cgccaacgta tccattgcgg tcccaggctt ccagaaccgt ttccagacgc
    22861 tgcacctcga cgcttactgt aacgaatgcg gcaactgcgc tcagttctgc ccgtggaacg
    22921 gtaaaccgta caaagacaaa atcaccgtct tcagcctgtc gcaagacttt gataacagca
    22981 gcaatcctgg cttccttgtg gaagattgcc gggtacgagt acgtctgaat aaccaaagct
    23041 gggtgttaaa catcgacagc gaaggtcagt tcaacaacgt accaccggag ctgaacgata
    23101 tgtgccgcat tattagccat gtccaccagc atcatcatta tctgctgggc cgcgtggagg
    23161 tgtaatcatg ttgattctga agaatgtcac cgcagtgcag ttacacccgg cgaaagtgca
    23221 ggaaggcgtt gatatcgcca tcgaaaatga tgtgattgtc gctatcggcg atgccctgac
    23281 gcaacgctac cccgatgcca gctacaaaga gatgcatggt cggattgtga tgccgggaat
    23341 tgtctgctcg cacaaccatt tttactcggg actgtcccgc ggaattatgg caaacatcgc
    23401 cccctgcccg gatttcatct caacgctgaa aaatctctgg tggcgactcg atcgcgccct
    23461 tgatgaagag tcgctctatt acagcggact gatttgttcc ctggaagcga ttaagagcgg
    23521 atgtacatcg gttatcgatc accatgcctc tccggcgtat atcggcgggt cgctctccac
    23581 attgcgcaac gcatttttaa aagttggcct gcgcgcgatg acctgttttg aaactactga
    23641 ccgtaacaac ggcatcaaag agttgcagga aggtgtagaa gaaaacatcc gcttcgcccg
    23701 tcagattgat gaggcgaaga aagcagcaac cgagccgtat ctggtggaag cacatatcgg
    23761 cgctcacgcg ccgtttaccg tgccggatgc cggtctggag atgctgcgtg aagccgtgaa
    23821 agccacaggt cgtggtttgc atattcacgc tgcggaagac ctttacgacg tttcctacag
    23881 tcaccactgg tacggcaaag acctgctggc acgactggcg caattcgatc tcatcgacag
    23941 caaaacgctg gtcgctcatg ggctgtactt gtcgaaagat gacatcgccc tactcaatca
    24001 gcgcgatgcg ttcctggtgc ataacgcccg ttcaaacatg aacaaccatg tcggctacaa
    24061 ccatcacctt agcgacatcc gcaatctggc gttgggaact gacggcattg gttcggacat
    24121 gtttgaagag atgaaatttg ccttctttaa acatcgcgat gcgggtggtc cgctgtggcc
    24181 tgacagtttt gccaaagcac tggctaacgg caacgaactg atgagccgca actttggcgc
    24241 gaaatttggc cttctggaag ccggttacaa agccgattta accatttgcg attacaactc
    24301 gccgacaccg ctgcttgcag acaatatcgc cgggcatatc gctttcggta tgggctcagg
    24361 cagcgttcat agcgtgatgg tcaatggcgt gatggtctat gaagaccgtc agtttaactt
    24421 cgattgcgat tccatttatg cgcaagccag aaaagccgct gccagtatgt ggcgtcggat
    24481 ggatgcgctg gcataaatga caaataccct cttcccgcag ggaagagggt taaataagga
    24541 aagaagatga ttgaacaatt tttcaggccc gactctgtcg aacaggcgct ggaactgaag
    24601 cgccgctaca aggatgaagc cgtctggttc gccgggggca gcaaactcaa cgctacacca
    24661 acccgtaccg ataaaaagat tgccatttcc ttacaggatc tggaactgga ctgggttgac
    24721 tgggataacg gtgcactgcg gattggtgca atgtctcgct tgcagccact gcgtgatgcg
    24781 cgatttattc ctgcagcact gcgtgaagcc ctcggttttg tttactcacg ccatgttcgt
    24841 aatcagtcga ccattggtgg tgaaatcgcc gcccggcagg aagagtcggt gctgcttccc
    24901 gtcctgctgg cactggatgc tgaactggtt tttggcaacg gcgaaacgct gtcaatcgag
    24961 gactacctgg cctgcccatg cgatcgcctg ctaaccgaaa ttatcattaa agatccgtat
    25021 cgcacctgtg cgacccgcaa aattagccgt tctcaggcag gtttaaccgt cgtgacggca
    25081 gccgttgcaa tgacagacca cgacggtatg cgaattgcgc tggatggcgt cgccagtaaa
    25141 gccctgcgtc tgcacgatgt cgaaaaacaa aatctggaag gcaatgcact tgaacaggct
    25201 gtcgccaacg ccattttccc gcaggaagat ttgcggggca gcgtggccta taaacgctat
    25261 atcacgggag ttctggtagc cgacctgtat gccgactgcc aacaggctgg ggaggaagcc
    25321 gtatgatcat ccactttact ttaaatggcg cgcctcagga gctaaccgtt aatccaggcg
    25381 aaaacgtgca aaagctgttg tttaacatgg gaatgcactc tgtacgcaac agtgatgatg
    25441 gctttgggtt tgccggttct gacgcaatta tctttaacgg taatatcgtt aacgcgtcct
    25501 tgcttatcgc cgcacagtta gagaaggcag atattcgtac tgcagaatct ctgggcaaat
    25561 ggaatgagtt aagtctggtt caacaggcca tggttgatgt tggcgtggtg cagtctggtt
    25621 ataacgatcc agctgcagct ctgattatca ccgatcttct cgatcgcatc gacgcaccta
    25681 cccgcgaaga gatcgacgat gcactctcag gtctgtttag ccgcgatgct ggctggcagc
    25741 aatactatca ggtcattgaa ctggcggttg cacgtaaaaa taatccgcag gccaccattg
    25801 atatcgctcc gactttccgt gacgaccttg aagtcattgg caagcattat cctaaaactg
    25861 atgccgcgaa aatggtgcag gcgaaaccct gctatgttga agaccgcgta acggctgacg
    25921 cctgcgtcat taaaatgtta cgtagcccac acgctcacgc actgattact catctggatg
    25981 tcagcaaagc tgaagcctta ccgggcgttg ttcacgttat tactcacctg aattgcccgg
    26041 atatctacta taccccgggc ggtcagagcg caccggaacc gtcaccgctt gaccgccgta
    26101 tgttcggcaa gaaaatgcgt cacgtcggcg atcgcgttgc tgcggtcgtc gcagaaagtg
    26161 aagaaattgc gctcgaagca ctgaagctca tcgacgttga atatgaagtg cttaaacctg
    26221 taatgtcgat cgacgaagca atggcggaag atgcgcctgt cgtgcacgat gaaccggtgg
    26281 tgtatgttgc tggtgcgcca gatactctgg aagacgataa cagccatgca gcccagcgcg
    26341 gcgagcatat gatcatcaac ttcccgatcg gttctcgccc tcgcaaaaat atcgccgcca
    26401 gtattcatgg tcatattggc gatatggaca aaggctttgc cgatgccgat gtgatcattg
    26461 agcgaaccta taactcaacg caggcgcagc agtgcccgac tgaaacacat atctgcttta
    26521 cccgtatgga cggcgatcgt ctggttatcc acgcctccac ccaggtacca tggcacttac
    26581 gccgccaggt cgcgcgcctc gtgggcatga aacaacataa agttcatgtc attaaagagc
    26641 gagttggcgg cggttttggg tctaaacagg acatcctgct ggaagaagtg tgcgcctggg
    26701 caacctgcgt gaccgggcgt ccggtactgt tccgctacac ccgtgaagaa gagtttattg
    26761 ctaacacctc tcgtcacgtc gcgaaagtca ccgtcaaact gggagcgaaa aaagatggtc
    26821 gcctgacggc agtgaagatg gatttccgcg ccaacactgg cccttacggc aaccactcac
    26881 tcaccgtacc gtgtaacgga ccggcgctgt cgctgccgtt atatccgtgc gataacgtcg
    26941 atttccaggt caccacctac tacagcaaca tttgcccaaa tggtgcttat cagggttatg
    27001 gcgcaccgaa aggtaacttc gctatcacca tggcattagc ggaactggct gaacagttac
    27061 agatcgacca actggaaatt atcgaacgta accgggtaca cgaagggcaa gagctgaaaa
    27121 ttctcggtgc aatcggtgaa ggtaaagcgc cgacctccgt tccttccgcc gccagctgcg
    27181 cactggaaga gatcctgcgt cagggtcgcg agatgatcca atggtcttca ccaaaaccac
    27241 aaaacggtga ctggcacatc ggtcgcggcg tcgccattat catgcagaaa tcgggtatcc
    27301 cggatatcga tcaggctaac tgtatgatca aactggaatc agacggtacc tttatcgttc
    27361 attctggcgg tgcggatatt ggtactggtc tggataccgt ggtgacgaaa ctggcagcag
    27421 aagtgctgca ctgcccaccg caggacgtgc atgttatctc cggtgatacc gatcatgcgt
    27481 tgtttgataa aggcgcatat gcctcgtccg gtacttgctt ctcgggtaac gcggcgcgtt
    27541 tggcagcaga aaatctgcgg gagaaaatac tgttccacgg cgcgcaaatg ttgggtgagc
    27601 cagtggcaga tgttcaacta gcaacgccgg gcgtcgtgcg cggcaagaaa ggcgaagtta
    27661 gtttcgggga tattgcccat aaaggcgaaa ccggcaccgg ctttggttca ctggtgggaa
    27721 ctggcagtta tatcacgcct gatttcgctt tcccgtatgg cgcaaacttc gctgaagttg
    27781 ccgtcaacac gcgtacgggt gaaatccgcc tggataaatt ctacgccttg ctggactgcg
    27841 gtacaccggt caatccagag ttagcgttgg gacaaatcta cggggccacc ctgcgtgcta
    27901 tcggccacag tatgagcgaa gagatcattt atgacgccga aggtcacccg ttaacgcgtg
    27961 atttacgcag ttacggtgca ccgaaaattg gtgacattcc gcgtgatttc cgcgctgtgc
    28021 tggtgccgag cgacgataaa gtcggcccgt tcggggccaa atcgatctcg gaaatcggtg
    28081 taaatggcgc agctccggcg attgctaccg caattcacga tgcatgcggc atctggttac
    28141 gcgaatggca tttcacaccg gagaaaatac tcaccgcgct ggaaaaaata taaataataa
    28201 atggccgctt cggcggcctg tttctctgtt tggacgatga ctaaatagtg actgcgaaaa
    28261 tgagataagc cgttctcaag gcgtcctgcg ccccaaattc gtgggaattt attttactga
    28321 ttcagatgat caaatttact ttaaaaggag tgaagggatg tctgatataa accatgcagg
    28381 ttctgacctt atatttgaac tggaggatcg ccctcccttt catcaggctc tcgttggtgc
    28441 cattacccat ctgttggcaa ttttcgttcc gatggtaacc cccgcgttaa tcgtgggtgc
    28501 ggccttacag ctttccgctg aaacaaccgc ttatctggtt tctatggcga tgatcgcctc
    28561 tggtattggt acctggttac aagtaaaccg ctacggcatc gtcggttctg gtcttctctc
    28621 aattcagtca gtcaattttt catttgttac ggtcatgatt gcgctgggca gcagcatgaa
    28681 aagcgacggt tttcacgaag agttaatcat gtcgtcgctc ctcggcgtct ccttcgttgg
    28741 cgcatttctg gttgtcggct cttcttttat cctgccctat ttacgtcggg ttattacgcc
    28801 tactgtcagc ggtattgtgg tactgatgat cggcttaagc ctgattaaag tcggcattat
    28861 cgattttggt ggaggatttg cagccaaaag cagcggtacg ttcggcaatt acgaacatct
    28921 cggcgttggt ttattggttt tgattgtggt gatcggcttt aactgctgtc gcagtccgtt
    28981 gctacgcatg ggagggatcg ccattgggct atgcgtcggt tatatcgcgt cgttatgcct
    29041 gggtatggtg gatttcagca gtatgcgcaa tttgccgtta atcaccatcc cgcatccatt
    29101 caaatacggg tttagtttca gcttccatca gttcctggtg gttggcacga tttatttgct
    29161 tagcgtgctg gaagctgtcg gcgatatcac cgccacggca atggtttctc gccgccctat
    29221 tcagggggaa gagtatcagt cccgactgaa aggcggcgtg ctggcagatg gtctggtttc
    29281 tgttatcgcc tccgctgtcg gttcattacc cttaaccacg tttgcgcaaa ataatggggt
    29341 tattcagatg actggcgtcg cttcacgtta tgtcgggcga accatcgcgg taatgctggt
    29401 tatcctcggc ttgtttccga tgattggcgg cttcttcaca accataccct cggcagttct
    29461 gggaggcgca atgacgttga tgttttccat gattgctatc gctgggattc gcatcatcat
    29521 caccaacggt ttaaagcgcc gagaaacact tattgtcgcc acttctttag gtttaggact
    29581 tggcgtctcc tacgatcccg aaatttttaa aatattgcca gcctctattt atgtactagt
    29641 tgaaaaccct atttgtgctg gcgggttaac tgcgatttta ttaaatatta tcctccctgg
    29701 tggctaccga caggaaaacg ttctgcctgg tattacctca gaggaagaga tggattaaca
    29761 gtaaaggagt caatgatgtc aggagaacac acgttaaaag cggtacgagg cagttttatt
    29821 gatgtcaccc gtacagtcga taacccagag gagattgcct ctgcgctgcg gtttattgag
    29881 gatggtttat tactcattaa acagggaaaa gtggaatggt ttggtgaatg ggaagacgga
    29941 aagcatcaaa ttcctgacac tattcgcgtg cgcgactatc gcggcaaact gatagtaccg
    30001 ggctttgtcg atacacatat ccattatccg caaagtgaaa tggtgggggc ctatggtgaa
    30061 caattgctgg agtggttgaa taaacacacc ttccctactg aacgtcgtta tgaggattta
    30121 gagtacgccc gcgaaatgtc ggcgttcttc atcaagcagc ttttacgtaa cggaaccacc
    30181 acggcgctgg tgtttggcac tgttcatccg caatccgttg atgcgctgtt tgaagccgcc
    30241 agccatatca atatgcgtat gattgccggt aaggtgatga tggaccgcaa cgcaccggat
    30301 tatctgctcg acactgccga aagcagctat caccaaagca aagaactgat cgagcgctgg
    30361 cacaaaaatg gtcgtctgtt gtatgcgatt acgccacgct tcgcccctac ctcatctcct
    30421 gaacagatgg cgatggcgaa acgcctgaaa gaagaatatc cggatacgtg ggtacatacc
    30481 catctctgtg aaaacaaaga tgaaattgcc tgggtgaaag aactttatcc tgaacatgat
    30541 ggctatctgg atgtttatca ccagtatggc ctgacaggta aaaactgtgt ctttgctcac
    30601 tgcgtccatc tcgaagaaaa agagtgggat cgtctcagcg aaaccaaatc cagcattgct
    30661 ttctgtccga cctccaacct ttacctcggc agcggcttat tcaacttgaa aaaagcatgg
    30721 cagaagaaag tcaaagtggg catgggaacg gatatcggtg ccggaacaac tttcaacatg
    30781 ctgcaaacgc taaacgaagc ctacaaagtg ttgcaactac aaggctatcg cctctcggca
    30841 tatgaagcat tttacctggc cacgctcggc ggagcgaaat ctctgggcct tgacgatttg
    30901 attggcaact ttttacctgg caaagaggct gatttcgtgg tgatggaacc caccgccact
    30961 ccgctacagc agttgcgcta tgacaactct gtttctttag tcgacaaatt gttcgtgatg
    31021 atgacgttgg gcgatgaccg ttcgatctac cgcacctacg ttgatggtcg tctggtgtac
    31081 gaacgcaact aataataaaa ctttaacatc ctcgtgagga catcattatg tctggagaca
    31141 tcctacaaac accggacgca ccaaagtcac agggcgcgct ggataattat tttaaaatta
    31201 ccgctcgtgg cagtaccgtt cgtcaggaag tactggctgg cttaacgacc tttctggcca
    31261 tggtttattc cgttatcgtt gttccgggaa tgctgggcaa agcaggtttt cctcccgcag
    31321 ctgtgtttgt tgccacctgt ctggtcgcgg gcttcggctc gttgctgatg gggttatggg
    31381 ccaatttgcc aatggcgatt ggttgcgcga tttccctgac ggcgtttacc gcattcagtc
    31441 tggtactcgg gcaacaaatt agcgttcctg tcgcactggg cgcggtcttt ctgatgggcg
    31501 tcatcttcac cgccatttcc gtaaccggtg tgcgtacctg gatcttacgt aatttaccga
    31561 tggggatagc tcacggtaca ggtatcggta tcggcctgtt tctgctgctg attgctgcta
    31621 acggtgtggg aatggttatc aaaaacccga ttgaaggctt gccagtggcg ctcggtgcgt
    31681 ttacctcctt cccggtgatg atgagcttgc tggggctggc ggtcatcttc ggtctggaaa
    31741 agtgccgcgt acccggcggg atcttgttgg tgattattgc aatttcgatc atcggcttaa
    31801 tctttgaccc agcggtgaag taccacggtc tggtggcgat gccaagcctg actggcgaag
    31861 atggtaagtc tctgattttc agcctcgata ttatgggcgc actccagcca actgtacttc
    31921 cgagtgtact ggcattggtg atgaccgcag tgttcgacgc cactggcacc atccgtgccg
    31981 tcgccggtca ggcgaatttg ttggataaag acaaccagat catcaacggc ggcaaagccc
    32041 tgaccagtga ctcagtaagt tcaatattct ccggtctggt gggcgcagcg cccgcagcgg
    32101 tttatatcga atcagcggca ggaaccgccg ccgggggtaa aacagggttg accgcaaccg
    32161 tagtgggggc gttattcctg ctgattttgt tcttatcacc gctgtcattt ttgatccctg
    32221 gttacgccac tgcacccgct ctgatgtacg taggtttgct gatgttaagt aacgtctcga
    32281 agctggattt caatgatttt atcgacgcaa tggctggcct ggtgtgtgcc gtgttcatcg
    32341 ttctgacttg taatatcgtt accggtatta tgctgggctt tgtgacactg gtcgtaggcc
    32401 gcgtctttgc acgcgaatgg caaaagctga atattggtac ggtgatcatt actgccgcac
    32461 tggtcgcgtt ttacgcgggt ggttgggcaa tctaatagat tctccgcgcc tttcagcgcg
    32521 gagatttctt tcagagagga ttctcaccgc tggcaacaat acgctgctgg cggactcgcc
    32581 tgagttctct ttcagtaagc aactgtagcg cctgtgtcgg gcaagattca acgcaggcag
    32641 gcccctcttc ccgctgttca cagagatcgc atttcacaat ttgttgccgg gtatcccccg
    32701 gcaacgactg aatggttatc atcccaaacg ggcacgcact gacgcaactc tgacagccaa
    32761 tacaacgggc agaattggcc tgcaccacct gctcgcccat cgtcagcgct cccacggggc
    32821 aagcgccaac acaaggggcg ttttcacact gatggcacat caccggcgca ctgatgcagt
    32881 ccagtcgctg taccttcagc cggggtaaaa agacatcggc attcaactcc tgttctgaag
    32941 ggtgagcgac cacacaggcc acttcacaag tacggcagcc aatacagtca gccggattaa
    33001 cgataattaa cgatttcatc accatgcctt cgtatcaaac agagttaaca tatcgcgcgc
    33061 cgcctgcctt cctgcggcca ttgcagtgac aaccagatcc gcgccatgaa ctgcatcccc
    33121 accagcaaag acttttttca ggtgcgtctg ggtaggtaaa tacccgacgt cgccggtttg
    33181 aatcaggccc catttatcga gtttaattcc gctgccctgc aaccacggca tggcatgcgc
    33241 ctggaaacca aaggccataa tcagaacatc ggcgggcaat tcaaattctg aacccgctac
    33301 cggacgagga cgacggcgac catccggccc cggctcaccc atggctgtac gaatcaggcc
    33361 caccgcagtt aaacgcccat cttcgtcaca agcgatatat tgcggctgaa cattgaactg
    33421 aaactcgaca ccttcctcgc gcgcattgac cacctctttg cgcgagcccg gcatactgac
    33481 ttcatcacga cgatacgcgc aggtcacgct gacggcattg aggcggatgg aagtccgcaa
    33541 acaatccatg gtcgtatcgc caccgcccaa taccacgacc cgcttacctt ccacatccgt
    33601 cagcggatac tcttcagact ccggcaaccc catgagctgg cgggtatggg cagtcaggaa
    33661 cggtagagcc tgaatgacac cgggcgcatc ttcatgcggc agatctgctc gcatcatccc
    33721 gtaagtcccc acgccgatga aaactgcatc atattcagaa gttaaatcgc taaaggtaat
    33781 atcgcggcca atttcacagt taagatgaaa gtcgattccc attgcggtga atatctctcg
    33841 ccgctggctt aataccgttt tatcgagttt gaaaggagga atgccaaaag tcagcatacc
    33901 gccaatttct ggatggcgat caaagacatc aacctgaact cctgcgcgcg ccagaatatc
    33961 agcacaccct aaccctgcag gcccagcgcc aatcaccgcc actttttcga tacggggaac
    34021 aactttgctg acatcgggac gccagcccat cgccagcgcg gtatcggtga tatagcgttc
    34081 cagattcccg atagagactg cgccagagtg atctttcaaa gtacatgcgc cttcacaaag
    34141 acggtcctgt ggacataccc tgccgcagat ttctggtaag gaactggtct ggtggcaaag
    34201 ttctgccgct tcaataatct ttccttcctg caccagacgg atgtaatccg gaatagcgtt
    34261 atgcagcggg caatgccagt tgcagttagc tttttcggcg caataaacac agcggtcact
    34321 ctcataagtc gcttgttgtg gatccagccc gtaatagatt tcgccaaagt gggttttccg
    34381 ttcactcgct gaaattttat ctgcgccttt acgcgagtta acggggagca acgctgcact
    34441 gcgagatggc tgagcgtctg atgacgcttt tcctgctgcc gttttgcgct ggcgggccac
    34501 ctttatctgc tgcaaccctt tatcgtccat cagccgtaac gcctgtgttg ggcagacttc
    34561 aatacaggct tgcgtgccgg aactgcgctg gttacaaagg tcgcatttct gcgcaatcgt
    34621 atcgaccatc tcaacgacgc caaaggggca agcgattgcg catcttttac aaccaataca
    34681 tttttgctcg tccagttgta cgctatcggg ctggaaagtc agagcattaa ccggacaagc
    34741 cgtaacgcaa ggggcattgt tgcagtgatg gcaggccacc ggattcgcag cctggccttt
    34801 ccctacaacg tggatacgcg gtcgaaagtc actgtgactc agcggccagt tttcttgatt
    34861 atgtgccatc gcacaggcaa tttcacaagc atgacagcct atacattccg cagcttcagc
    34921 agcgataaac ttattcattt gcatcccttt catttaatga gttatgtctt ctcaaatttc
    34981 gcgatgcaat aaatgggcat atattaggta gcatggccga tttaattata attttgcgac
    35041 tgagttcaaa ttattgcccc tcaatctgtg ccgctttcat tatttcaaca ttgccgacca
    35101 aaagagatct aaccagataa aaacgattaa atacgagagt gcgacatgcc agaatgatta
    35161 atgaaatatc aatatgagaa aattacagat aattccattg tcaggttctc ttctcatttt
    35221 cgtggtttaa ccacgattat gtgattgcct ccgcaattcc tgtctctaac tccccttcct
    35281 cgcaaaaact ggcactccac gagcatgtgt ttagacagtt tcattaacgt aaacggttgc
    35341 tttttactct ggcgggcgaa aggagaaaca ctgatgagcg ccatagattc ccaacttccc
    35401 tcatcttcag ggcaagaccg cccaactgat gaggttgacc gcatattatc accaggaaag
    35461 ctgatcatac tcggtctgca acacgtcctt gtcatgtacg caggtgcagt cgctgttcct
    35521 cttatgattg gtgaccgact gggcctctca aaagaagcta ttgcgatgct cattagctcg
    35581 gatctctttt gctgcgggat cgtcacatta ttgcaatgta tcggtatcgg ccgctttatg
    35641 gggatccgcc tgccggtgat tatgtcggtg acctttgctg ctgtaacacc aatgatagcc
    35701 attgggatga acccggatat cggcctgctg gggatatttg gtgccactat cgccgcgggt
    35761 tttatcacca cattattagc gccacttatc ggtcgcttga tgcctttatt cccgccactg
    35821 gttaccggtg tggttattac ttctatcgga cttagcatca ttcaggtggg tattgactgg
    35881 gccgcaggag gtaaagggaa tccgcaatat ggtaatcccg tttatttagg tatctccttt
    35941 gccgtcttaa ttttcatctt gctcattact cgctatgcga aaggatttat gtccaacgtc
    36001 gccgtattac tggggattgt atttggcttt ttactttcgt ggatgatgaa tgaagtcaat
    36061 ttatccgggc tacatgatgc ctcgtggttt gcgattgtta cgccgatgtc gtttggtatg
    36121 ccgatttttg atcccgtttc cattctgacc atgactgccg tgttaatcat cgtgtttatc
    36181 gagtcgatgg ggatgttcct ggcactgggt gaaatagtcg gtcgtaaact ctcttcacac
    36241 gatattattc gcgggctgcg tgtcgatggc gtagggacaa tgataggcgg aacgtttaac
    36301 agctttcccc acacgtcatt ttctcaaaac gttggcctgg ttagcgtgac gcgcgttcat
    36361 agccgctggg tgtgtatttc ttcgggaatt atattaatcc tgtttggcat ggtgccaaaa
    36421 atggcggtgc tggtcgcctc cattccgcaa tttgtgctgg gcggtgctgg gctggtgatg
    36481 ttcggcatgg tactggcgac agggattcga attctgtcgc gctgtaacta caccaccaat
    36541 cgttacaacc tctatattgt ggcgatcagt ctcggcgttg gcatgactcc gacgctctct
    36601 cacgatttct tttctaagtt accggccgta ctgcaaccgt tgctgcatag cggcattatg
    36661 ctcgcaaccc ttagcgccgt tgtgctgaac gtcttcttta atggctatca gcatcatgct
    36721 gatctggtga aggaatccgt ctctgataaa gatttaaaag tcaggacagt acgtatgtgg
    36781 cttctgatgc gcaagctgaa gaaaaatgag catggagaat aatatgaatc ttttaatgcg
    36841 cgctatattc agtctgttgt tgctttttac tctctctatt cctgtcattt ctgactgtgt
    36901 tgcaatggcc attgaaagtc gcttcaaata tatgatgctg cttttttaaa tggtttttac
    36961 ctgtcgacat ccgctcaaaa cgggcggttg tcgataaacg ctcacttggt taatcatttc
    37021 actcttcaat tatctataat gatgagtgat tagaattaca tgtgagaaat tatgcaaacg
    37081 gaacacgtca ttttattgaa tgcacaggga gttcccacgg gtacgctgga aaagtatgcc
    37141 gcacacacgg cagacaccct cttacatctc gcgttctcca gttggctgtt taatgccaag
    37201 gggcaattat tagttacccg ccgcgcactg agcaaaaaag catggcctgg cgtgtggact
    37261 aactcggttt gtgggcaccc acaacaggga gaaagcaacg aagacgcagt gatccgccgt
    37321 tgccgttatg agcttggcgt ggaaattacg cctcctgaat ctatctatcc tgactttcgc
    37381 tatcgcgcca ccgatccgaa tggcattgtg gaaaatgaag tgtgtccggt atttgccgca
    37441 cgcaccacca gtgcgttaca gatcaacgat gatgaagtga tggattatca atggtgtgat
    37501 ttagcagatg tattacgcgg tattgatgcc acgccgtggg cgttcagtcc gtggatggtg
    37561 atgcaggcag ccaatagtga agcaagaaaa ttgttgtctg ctttcgcgca gcacaattaa
    37621 aaaaccccga catttgccgg ggttgtgagc ataacgtaat gcttatttta ccggacgcat
    37681 cgccgggaac agaataacgt cgcggatggt atggctgttg gtgaacagca ttaccatacg
    37741 gtcgatacca attcccagac ctgctgtcgg cggtaagccg tgttccagtg cggtgacata
    37801 atcttcgtcg tagaacatcg cttcgtcgtc gcctgcgtct ttcgcggcaa cctgatccag
    37861 gaagcgctgc gcctgatctt ccgcgtcatt cagctcgcta aagccgttac cgatttcacg
    37921 accaccaatg aagaactcaa agcggtctgt gatttccggg ttaacgtcgt tacgacgcgc
    37981 tagcggagaa acttctgccg gatattcagt aatgaaggtc ggctgaatca gatgtgcttc
    38041 tgccacttct tcgaagatct cggtaacgat acggcccaga ccccagctct tttcaacgtg
    38101 gatgccgata gattcagcaa tcgctttcgc agagtcgaag ttatccagat ccgccatgtc
    38161 ggtttccggg cgatatttct tgatcgcttc acgcatggtc agtttttcga acggtttacc
    38221 gaagtccagc gttacgtcgc cgtaggtcac ttccgtctta ccgagaatat cctgtgccag
    38281 agtacggaac agcgattcgg tcagctcgat cagatctttg taatctgcgt aagccatata
    38341 gagttccatc atggtgaact ctgggttatg acgtacggaa ataccttcgt tacggaagtt
    38401 acggttgatt tcgaatacac gctcgaagcc accgaccacc agacgcttga ggtacagttc
    38461 cggcgcgata cgcaggtaca tgtcgagatc cagcgcgtta tggtgggtga taaacggacg
    38521 cgcagcggca ccgccaggga tcacctgcat catcggcgtt tcaacttcca taaagccgcg
    38581 gttcaccatg aactggcgaa taccagagag gatctgcgag cgcactttaa aggtgttgcg
    38641 ggattcatcg ttagagatga gatccagata acgctgacga tagcgcgctt cctgatcctg
    38701 caagccgtgg aatttgtccg gcagcggacg cagtgctttg gtcagcagac gcagctcggt
    38761 gcagtggata gacagttcgc cggttttggt tttgaacagt ttacctttcg cgccgaggat
    38821 gtcgccgagg tcccattttt tgaactgctc gttgtaaacg ccttccggca gatcgtcacg
    38881 ggcaacgtac agctgaatgc ggccacccac atcctgcagg gtaacgaaag acgctttacc
    38941 cataatacgg cgggtcatca tgcggccagc aacggcaact tcgatgttca gcgcttccag
    39001 ttcttcgttc tctttaccgt cgaattctgc gtgcaattgg tcagaggtat gatcgcgacg
    39061 gaaatcgttc gggaaggcaa tcccctgctc gcgcaggttc gccagcttct cacgacgcgt
    39121 tttcagttca ttgttaagat cgactaccgc gtcagcgccc tgtgcgtgtt gttcagacat
    39181 gttggttcct cataaccctg ctttcaaact tgcttcgata aattgatcca ggctgccgtc
    39241 cagcacggcc tgcgtgttgc gggtttctac cccggtacgc agatctttaa tgcgggagtc
    39301 atcaaggaca taagaacgaa tctggctgcc ccagccgatg tcggatttat tgtcttccat
    39361 cgcctgtttc tcggcatttt tcttctgcat ctccagttca taaagcttcg ctttcatctg
    39421 cttcatggcc tggtctttgt tcttgtgctg ggaacggtcg ttctggcact gagtcacgat
    39481 cccggtcggg atgtgagtaa tacgcaccgc agattcggta cggttaacgt gctgaccgcc
    39541 cgcgccggac gcgcgataaa cgtcaatgcg cagatccgcc ggattgattt cgatatcgat
    39601 atcgtcatca acttccgggt aaacaaacgc ggagctgaac gacgtgtggc gacgaccgcc
    39661 ggagtcaaac gggctcttac gcaccaggcg gtgaacgcca gtttctgtac gcagccagcc
    39721 gtaagcgtaa tcgccggaga ttttgatcgt tacggattta atacccgcca cttcaccttc
    39781 cgactcttcg atgatttcag ttttgaaacc acgcgactcc gcccagcgca gatacatacg
    39841 ctcaagcatg ctcgcccagt cctgtgcttc cgtgccgcca gaccccgcct gaatatcgag
    39901 gtagcagtcg gcgctgtcat attcgccaga gaacatacgg cggaactcaa gctgcgccag
    39961 tttttcttcc agggcgtcga gttcagcaac ggcttcgtta aaggtttctt cgtcgtcagc
    40021 ttctacagcc agttccagca gaccagaaac atcttccagc ccctgtttca tttggtcaag
    40081 ggtgtcgaca acggcttcga gggaggaacg ctctttaccc agcgcctgtg cgcgttcggg
    40141 ttcgttccag acatccggct gttccagctc ggcgtttact tcttccagac gctctttctt
    40201 ggcgtcatag tcaaagatac cccctaagaa cgtcggagcg ttccgtgagg tcctgaatgc
    40261 gattatttac cggattaatt tcaaacatgg tctgatttct tttcttgagc tagtcaaaat
    40321 gcggtgataa gagcgggatt gtacccaatc cacactcttt tttatagaga agatgacgct
    40381 aaattggcca gatattgtcg atgataattt gcaggctgcg attgccgcga aactcgttga
    40441 tatcaagctt ataagccagt tgcacttcgc gcacgccgtt atccggccaa agggcggtat
    40501 caacgttaaa ggcaatgccg tccagcagcg ggccgccgcc gaccggttca accatgacct
    40561 tcaaatggcg ctcgcccacc agtcgttgtt gcagaaggcg gaaatgaccg tcaaacagcg
    40621 gttccgggaa catctgtccc cacgggccag catcgcgcag taactgcgcc acttccatgg
    40681 tcatttcggc cgggcttaac ggaccgtctg acaccacttc gccttgcaat agtgaagggt
    40741 ccagccactc agtcaccagt tcgccaaagc gttgctgaaa gagttcgaat ttatcctctt
    40801 ccagtgacag cccggccgcc attgcatggc cgccaaactt aagcatcata ccggggtaga
    40861 gcgtgtccag ccgctccagc gcatcgcgca tatgcaaccc ctgaatggaa cgaccagaac
    40921 ctttcagcgt accgtcgccc gcaggggcaa aggcgataac cggacggtga aaacgctctt
    40981 tgatacgcga tgccagaatg ccaacaacgc cctgatgcca ttcagggtga tacattgcca
    41041 gcccgccggg tagcgtgtca cggctgcgct ccagtttctc gcacagggtc agggcttcaa
    41101 cctgcattcc ttgttcgatc tcttttcgcg tctggtttag cgcatcgagt tcatttgcca
    41161 gcacgcgcgc ttcgccgatg ttgtcgcaca gcaacagtgc cacaccaacg gacatatcat
    41221 ccagtcgccc ggcagcattg agacgtggcc ccagcgcaaa acctaaatcg ctggcggcga
    41281 gtttttgtgc atcacggttg gccacttcca gcagcgcttt aatccccgga cggcactttc
    41341 cggcacggat gcgactcatc ccctgccacg tcagaatgcg attattagcg tccagcggca
    41401 cgacgtccgc cactgttccc agcgcgacca gatccagcag ttctgccaga ttaggaattg
    41461 cgatgccgcg ctcatcaaac cagccctgat cgcgcaaaaa agtgcgcaga gccagcatca
    41521 gataaaacgc cacacccacg cctgccagtg atttcgacgg gaaattacag tcgcgcaagt
    41581 tagggttaat gatcgcttcc gctgcgggta atgtgtcgcc cggcaaatgg tgatcggtaa
    41641 caataaccgg gatgcccaac gagcgagcat gttcaacccc cgcatgggag gaaataccgt
    41701 tatccaccgt gacaattaac tgcgcgccac gggcatgggc ctgatcgacc acttccgggc
    41761 ttaagccgta accgtcttcg aaacggtttg gtaccaggta gtcgatattg ctgcaaccaa
    41821 gcgagcgcat cgccagcacg cttagagccg tgctggtcgc gccgtcggcg tcgaaatcac
    41881 cgaccacaat aatccgcgtt ccttcgcgaa aagcgttgta aaggatctca acggcctttt
    41941 cgacgccgct cagttgctgc cagggcaaca tacctttaac actgcgtttc agttcttgcg
    42001 cactgcgtac tccccggctg gcgtataaac ggcgcagcaa gggaggcaat tcagcgggca
    42061 agtctgccgt ttcatcgact tcacggcgac gaagttgtat ctgttgtttc acgcgaatta
    42121 tttaccgctg gtcatttttt ggtgttcgtc gaggaattct ttcatgtctt tcggtggctg
    42181 gtaacccgga acaagtgtgc cattgctcag cacaattgcc ggagtgccgc taacgccaag
    42241 ctggacgcca agtgcgtaat gatcggcaat atcgatatcg caacttgccg gagtggcagc
    42301 tttaccagcc atcacatcat caaacgcttt gtttttatct ttcgcacacc agatggcttt
    42361 catttgttgc tcagcctggc tctccagccc ctggcgtggg aaagcaagat aacgcacggt
    42421 gatccccagt gcgttgtagt ctgccatttg ctcatgcagt ttgtggcagt aaccacaggt
    42481 aatatcagta aacacggtga tgacgtgttt ttcctgtggc gctttataaa cgatcatctc
    42541 tttttcaagc gcattcaact gctttaacag catcttattg gtgacattga ccggagctgt
    42601 gccactaacg tcatacattg gcccctgaat gatatgttta ccatcatcgg tgatgtacaa
    42661 cacaccgctg ttagtcagaa ctgtcttcat gccagctacg ggcgcgggct gaatatcgct
    42721 gcttttgatg cccattttgg ctaacgtttg ttgaattgcc gcgtcatcag cctgagcaaa
    42781 gcctgaaaac gccgctaaca aagtaaacaa cataaaacct ttcttcataa atcttcccgt
    42841 tcttttcaga catcacgccc gcgggtgatg ctgttgatga agttgccgca gacgctcggt
    42901 agcgacatgc gtataaattt gcgtggtgga gagatcgctg tggcccagta gcatctgcac
    42961 cacgcgtaaa tccgcaccat gatttaataa atgagtggca aaagcgtgac gcaagacatg
    43021 cggtgacagc ttttcgctgt cgatacccgc cagcacggca taatgtttaa tgcggtgcca
    43081 gaaggtctgt cgcgtcatct gctgcgcacg ctggctgggg aacaacacat caatagagac
    43141 accgttcaac aaccacggtc gcccatgctc gagatacgtt tccagccagt aaaccgcctc
    43201 ttcacctaac ggcaccaggc gctctttgtt gcctttacca atgacccgca ctacgccctg
    43261 acgcaggctg atatcactca ttgtcagccc gaccagttca gagacacgca gcccggtagc
    43321 atacaacact tcaagcatgg ctttatcgcg tagctccagt ggctgatcaa ttaatggtgc
    43381 ctgtaataaa cgttcgacct gcgcttcgct taaatctttt ggcaaacgct ggggcaattt
    43441 cggtgaagca agatgcgcac tgggatcgtc ttcacgaaac ttttcgcgat aaagatactg
    43501 gaacaatcgg cgcactgcac tcagcaaacg cgctgagctg gtggctttat acccgccctc
    43561 cagccgttct gccagtaatg cctgcaaatc gtcactttgc gccgtcgcca gcgtcaaccc
    43621 gcggtgatgc aaccactcca ccatcattga cagatcgcga cggtaagcgt tcaacgtatt
    43681 ttcagccaga tttttttcca gccacagagc atcaagaaac tgctcgatgc gtgccagatc
    43741 ctgtttcact tgcgcccctt atggtcactc atttgatcca ttatgcctta ttgtgccgtg
    43801 actaaagcga ttctgataca ctagccacaa aagccacagc agaatcgaga agcttacgtt
    43861 atgaatatgg gtctttttta cggttccagc acctgttaca ccgaaatggc ggcagaaaaa
    43921 atccgcgata ttatcggccc agaactggtg accttacata acctcaagga cgactccccg
    43981 aaattaatgg agcagtacga tgtgctcatt ctgggtatcc cgacctggga ttttggtgaa
    44041 atccaggaag actgggaagc cgtctgggat cagctcgacg acctgaacct cgaaggtaaa
    44101 attgttgcgc tgtatgggct tggcgatcaa ctgggatacg gcgagtggtt cctcgatgcg
    44161 ctcggtatac tgcatgacaa gctctcgacc aaaggcgtga agttcgtcgg ctactggcca
    44221 acggaaggat atgagtttac cagcccgaaa ccggtgattg ctgacgggca actgttcgtg
    44281 ggtctggcgc tggacgaaac taaccaatat gaccttagcg acgagcgtat tcagaactgg
    44341 tgcgagcaaa tcctcaacga aatggcagag cattacgcct gatgtcactg acggcttagc
    44401 gcatatgctt tgccgtcatc tttatctttg cgtctcttgt tgcaacaata tccgccgtaa
    44461 atcccgccat tcggcttcgt ccatgctgtc ggctgccagc cataaatgtt gccgtttacc
    44521 gctgtcagaa cgtaaacgca gcatcatgcc gctcttaatc atccacggcg ctttgacgat
    44581 gctccactcc tgcccttgcc agcgcaaacg cccgtccatc aacaggcgaa tttccccctg
    44641 gcgagcatta atgcgccgct ggctgcgaac gcaatcaaac accaccagcg aaagtaacac
    44701 catccataac ggggtgtaac tgagcggcca gggcatgagt aaaataacag cggcaaccag
    44761 cccgtggatc agcaaggaaa gccactgtgc gcgccaggag acgcgcagat cagattgcca
    44821 caggaccacg ttcccggttc cgtgtctgga tgagtcggac catcatttcc agttctgcat
    44881 cggccggttt accgtggttc atcagccagt taaacagatc gggatcgtca cactccagca
    44941 gacgaataaa gatgcgtttt tcgtcatcgc ttaagctgtc gtactcatgt tcgaaaaacg
    45001 gcatgattga aatatcgagt tcgcgcatac cacggcggca tgcccaatga atgcgggctt
    45061 tgttgttaat gtccatcttc ttcctgtctc acgaaaatcc agtacctggc tattgtaacg
    45121 tgtttttcga cttcttttgc gggaatatca gtaaacacaa tcgcgatcgc gaaattaatt
    45181 cacaacaatt caagggcttc atttttttgg aagtcgcctc gcagaaggca cagatcgcgt
    45241 agtgaaagca cttgcattgc ctcatagctc ttttaccatt agtcattaat acgccgttaa
    45301 gcaactcagg actctattat ggcttttaca ccttttcctc cccgtcagcc tacggcgtct
    45361 gcccgtttac cgctgacgct gataacgctt gatgactggg cgcttgccac cattactggc
    45421 gcggacagcg aaaaatatat gcagggtcag gtgacagcag atgtcagcca gatgacagaa
    45481 aatcagcatc tgctcgccgc ccattgcgac gccaaaggta aaatgtggag caatttacgt
    45541 ctgttccgcg acggcgatgg ctttgcatgg attgaacggc gcagtgtgcg tgaaccgcag
    45601 ctgactgaac tgaaaaaata tgcggtgttc tctaaagtga ccatcgcgcc ggacgatgag
    45661 cgtgtgctgc ttggtgttgc cggttttcag gcgcgcgccg cgctggcaaa tatctttagt
    45721 gaactgcctt cgaaagaaaa acaggtagtt aaagaaggcg cgaccacttt gctatggttt
    45781 gaacaccctg cagaacgttt cctgatcgta accgatgaag ccactgccaa tatgctgacc
    45841 gataaactgc gcggtgaagc ggaactgaac aatagccaac agtggctggc attaaacatt
    45901 gaagcgggtt tcccggtgat tgatgccgcc aacagcgggc agtttatccc acaggcgacc
    45961 aacctccagg cgctgggcgg cattagcttt aaaaaaggct gctataccgg acaagagatg
    46021 gtggcgcgag ctaaattccg tggtgccaac aaacgcgcgc tctggttgct gacgggtagc
    46081 gccagccgac tgccggaagc cggtgaagac ttagagctga aaatgggcga gaactggcgt
    46141 cgtaccggaa ccgtgctggc tgcggtaaaa ctggaagatg gtcaggtcgt ggtacaggtc
    46201 gtcatgaata acgatatgga accggacagc atcttccgcg tgcgtgacga tgcgaataca
    46261 ttgcatatcg agccgctgcc gtattcactc gaagagtaaa tctctgtgtc gcatcatgca
    46321 tttatcgcct gatgcgacaa gggtgtgtct tttcaggcct acaaaggcac acccattacg
    46381 cctgcccaat atataaatag atcgccagaa agtggcacac gctgccgccg agcacaaagc
    46441 cgtgccagat ggcatggttg tagggaatgc gtttgcagac gtagaaaatc accccgagcg
    46501 agtaaaccac gccgcctaca gccagtaagg taacgctgcc cgccgcaagc ttaattgcca
    46561 tttcataaat caccaccagc gacagccagc ccatcgccag ataggtcacc agagataaaa
    46621 ttttgaatcg gtgcgcgatg gtcagtttga acagaatccc cagcaatgcc aggctccaga
    46681 taacaatcat caacccgcgc gctaacggag aatccagccc caccagcaaa aacggcgtgt
    46741 aggttccggc aatcaatagg taaatagcgc aatggtcaaa tttcttcagc cacatttttg
    46801 cccgttgatg aggaatggcg tgatagagcg tcgaagcgag gaacagcagg atcatactgc
    46861 caccatagag gctgtaactg gttatcgctg tggcgctggc attgagatcc accgcctgaa
    46921 ccagtagcaa caccagccca acgataccaa acaccaaccc aatgccgtga ctgacgctgt
    46981 tggcaatttc ctctgccagc gaatatccct gcttaatgag gggcttctga accataactt
    47041 actccggaga aacgtacacg cacatgtata cctctccagc gtaactgaga atagttccag
    47101 tgaacacctg ttagctaaaa taaattctga tttgggacta atctcctaaa aatcatgaaa
    47161 ttaaatgcaa aatttcaact aacaggcgtg agttcaattt aaaggcattt aaattcaatc
    47221 acataaaact gtgtctggcc gggatagatg tcggcaatga cctttttcag ttctagcagg
    47281 gtcatattct cctgctctgc atgtttttcc gtcagcgtat ccagcgttac ggttgaggtt
    47341 gcggtgactt caatcgtgca aaaataaccg tcatcttcaa aacgcccgac acgaagcaca
    47401 tcacccgttt tgaagtgcga ttcagactcg tcgcggatgg tgatagtttt acgcccagcc
    47461 agaatgtcat cctggaaacg ttgaaaaaaa gtgatgtcgt ttggctgcat ggtactattt
    47521 cctgtaagaa ttgactcatc tggagcctat gatagtgaaa aaactcacct taccgaaaga
    47581 tttcttatgg ggcggcgcag ttgccgctca tcaggtcgaa ggcggctgga acaaaggcgg
    47641 caaagggccg agcatttgtg acgttctgac cggtggcgca cacggcgtgc cgcgcgaaat
    47701 caccaaagaa gtgttgccag gaaaatacta tccgaaccat gaagccgttg atttttatgg
    47761 tcattacaag gaagacatca agctatttgc cgaaatgggc ttcaaatgtt ttcgtacatc
    47821 catcgcctgg acgcgcattt ttccaaaagg tgatgaagct cagccaaacg aagaagggct
    47881 gaagttctac gatgatatgt tcgatgaact gctgaaatac aacatcgaac cagtgatcac
    47941 cctctcccac tttgaaatgc cgctgcatct ggtgcagcaa tacggtagct ggaccaaccg
    48001 taaagtggtt gatttctttg tccgtttcgc ggaagtggta tttgaacgct ataagtataa
    48061 agtcaaatac tggatgacct tcaacgaaat taacaaccag cgtaactggc gtgcaccgct
    48121 gttcggttac tgctgctccg gcgtggttta taccgagcat gagaacccgg aagagacgat
    48181 gtatcaggtg ctgcatcacc agtttgtcgc cagcgccctg gcggtgaaag ccgcgcgtcg
    48241 cattaacccg gaaatgaaag tcggctgtat gctggcgatg gtgccgcttt acccttactc
    48301 ctgtaatccg gacgatgtga tgttcgccca ggagtcgatg cgcgaacgct acgtctttac
    48361 cgatgtgcaa ctgcgtggct attacccgtc ctatgtgttg aacgagtggg agcgtcgcgg
    48421 atttaacatc aaaatggaag acggcgatct cgatgtgctg cgcgaaggca cctgcgatta
    48481 tctcggtttc agctattaca tgaccaacgc ggtgaaggcc gaaggcggca ccggcgatgc
    48541 gatctctggt tttgaaggca gcgtaccaaa cccgtatgtt aaagcgtctg actggggctg
    48601 gcagattgat cctgtgggtc tgcgctatgc actttgcgaa ctgtatgagc gttatcagaa
    48661 gccgctgttt attgtcgaaa acggttttgg cgcttacgac aagatggaag aagatggcag
    48721 catcaacgac gactaccgca ttgactacct gcgcgcccat attgaagaga tgaaaaaagc
    48781 ggtgacttac gatggcgtgg atctgatggg ctacacaccg tggggctgca tcgactgcgt
    48841 gtcgttcact accgggcagt acagcaaacg ctacggcttt atctatgtga ataaacatga
    48901 cgacggtact ggcgatatgt cgcgttcacg taagaagagc tttgactggt acaaagaggt
    48961 gattgccagc aacggcgaga agctttaatt acccgatgtg cctgatgcgc cccgctcatc
    49021 aggcctggcg ctcctgtcat atattgaact ccaggagttt atatttacgc ttcatccgac
    49081 acacaaagcg cactttatta acaagctaaa aaggcgccga agcgccttta gaagatagtc
    49141 gaatcagtaa attactggta ttcgctaatc ggtacgcagg agcagaacag gttacggtcg
    49201 ccgtaaacat catccagacg tttcactgtc ggccagtatt tgtctgccac gcctgccggg
    49261 aataccgcaa tttcacggct gtacggatgc gcccactcgg cgaccagttc gctctgaatg
    49321 tgcggcgcgt tcaccagcgg gttatcttcc agcggccagg ctccggcttt cacctggtcg
    49381 atttctgcgc ggatagccag catcgcgtcg ataaagcgat ccagttccac tttgctttca
    49441 gattcagtcg gttcaaccat cagcgtaccc gccaccggga acgacatcgt cggcgcgtgg
    49501 aaaccgtagt cgatcagacg cttggcaata tccagttcgc tgatgccggt ttcttctttc
    49561 agcggacgaa tatcaagaat acattcgtgc gccacgcgac cgtcgcgacc ggtatacagc
    49621 actgggaaag catcctgcag gcggctggca atatagttgg cgttaagaat tgccacctgg
    49681 cttgcttttt tcagcccttc tgcgcccatc atgcggatgt acatccagct gattggcaga
    49741 atggatgcgc taccgaacgg tgccgcagaa accgcgccct gacgggttaa catgccttca
    49801 atttgtacca cgctatgacc tggcacaaac ggtgccagat gcgctttcac gccgatcggt
    49861 cccatacctg ggccgccgcc accgtgcgga atgcagaaag ttttatgcag gttaaggtgc
    49921 gaaacgtccg cgccaataaa gcccggtgag gtgatgccga cctgggcgtt catgttcgcg
    49981 ccatcaaggt aaacctgacc gccgaactga tgcacgactt cacacacttc acggatcgtt
    50041 tcttcgtaca cgccgtgggt ggaaggataa gtcaccatga tgcaggagag attatcgccc
    50101 gcttgttccg ctttcgcgcg caggtcagtc agatcgatgt tgccattttt atcacatgcc
    50161 acaactacca cctgcattcc tgccatatgt gcagaagcgg ggttagttcc gtgcgcagaa
    50221 gccgggatca agcagatatc gcgatgccct tcgttgcggc tttcatgata atgacgaatc
    50281 gccagcaggc ccgcatattc gccctgtgcg ccagagttcg gctgcataca aacggcgtcg
    50341 taaccggtca gtttcaccag ccagtcagcc agttgcgcaa tcatctgctg ataaccttcg
    50401 gcctgttccg gcgggcagaa cgggtgcagt tcggcaaatt ccggccaggt gatggggatc
    50461 atctcggcgg cggcgttcag tttcatggtg caggaaccca gcgggatcat cgcctgattc
    50521 agcgccagat ctttacgctc cagcgagtgc atatagcgca tcatttcggt ttcgctgtgg
    50581 tagcgattaa acaccggatg ggtgaggatt tcgtcgtcgc gcaacattgc aggctgaata
    50641 gagcggctat cgtgagccac gtctttgtcc agcgtgtcga tgtccagtcc gtggttatcc
    50701 cccagcagta cgctgaaaag ctgcatcacg ttttcgcgcg tggtggtttc atcaagggtg
    50761 atcccaaccg cgttcaggat atcgctacgc aggttgattt cagccgcttc ggcacgcgcc
    50821 agtacgcccg ccttgtcggc cacttccaca cacagagtgt cgaaatagtg cgcatggcgc
    50881 agcttcagac ctttttgttg caggcctgcc gccaggatat cggtcagacg gtgaatgcgg
    50941 ttagcgatac gtttcaggcc aaccgggccg tgataaacgg catacaggct ggcgatgttt
    51001 gccagcagca cctgggaagt acaaatgttg gagttcgctt tctcacgacg aatatgttgc
    51061 tcgcgagtct gcatcgccat gcgcagagcg gtgttgccag ctgcatcttt cgatacaccg
    51121 ataatacggc ccggcattga gcgtttgtat tcgtctttcg ccgcaaagaa tgccgcgtgt
    51181 gggccaccgt agcccatcgg tacgccaaag cgttgcgccg aaccaaaaac aatatccgcg
    51241 ccctgtttac ccggcgcagt taacagcacc agcgccataa tatcggcggc gacactgacc
    51301 acaattttgc gtgatttcag ttcgctaata agcgtggtgt agtcgtgaat ttcaccagta
    51361 gtgccgacct gctgtaacag cacgccgaag acgtcctggt ggtcgagcac tttttgcgcg
    51421 tcatcgacaa tcacttcaaa accaaaggtt tcagcacgag tacggaccac atcgagcgtt
    51481 tgcggatgaa cgtcagaagc aacaaagaag cggttggcat ttttcagttt gctgacgcgt
    51541 ttagccatcg ccattgcttc ggcggcagcg gtggcctcgt ccagaagaga agcagaggcc
    51601 atatccagtc cagtcaaatc cagcgttacc tgctggaagt tgagcagtgc ctcaaggcgg
    51661 ccctgggaga cttcaggttg atacggagta tacgcggtat accagcccgg attttccagc
    51721 atgttacgca gaataaccgg cggtagctgc acggcggtgt aacccatgcc gatgtaagac
    51781 gtgaagcgtt tattgcgact ggcaatagcc ttgagttccg ccagcgcggc gtattcggtc
    51841 gccggtgcgc caacctgcgg cggggtcgca agctgaatat ctttcggtac aatctggccg
    51901 gtcagcgcgt ttaacgattg tgcgccaacg gcattcagca tttcttgctg ttgcgcggcg
    51961 tccggtccga tatggcgttc aataaaagcg ccgctgtttt caagctggct taacgtctgt
    52021 gtcatgagcg atggttcctg aaacgtgcag tgaattgtga acctctctcc ttgcgaagag
    52081 agtgagggtg aggcgtaaaa gttcctcacc ctgatcctct cccgcagaag aggaataaag
    52141 ccgttactcg tcttctaaca atgcttcgta tgcggtcgca tccagcagtg attccagttc
    52201 gctttcatcg ctggctttga ttttaaagat ccagccgcct gcatacggtt cgctgttcac
    52261 cagttccggg gaatcgctca gtgcgtcgtt taccgccacg atttcaccgc ttactggcgc
    52321 ataaatgtct gacgccgctt ttaccgattc ggcaaccgcg cagtcatcgc ccgcgctaac
    52381 cgttgcgccc acttccggca ggtcaacaaa caccatatcg cctaacagct cctgggcatg
    52441 ttcggtgata ccaacggtgt aagtgccgtc ggcttcttta cgcagccatt cgtgttcttt
    52501 gctgtatttc agttctgctg gtacgttgct catcaatcaa tctccaaaaa agtaaatcac
    52561 gcgacggctt taccgttacg cacaaaaaca ggtttcgtca ctttaaccgg catttcacgg
    52621 ttgcgaattt gcacaatcgc cgtttcacca ataccttccg gcacacgcgc cagcgcaatg
    52681 ctgtaaccca gcgtcgggga gaaagtaccg ctggtgataa tgccttcatg ctggttgccc
    52741 tgcgcatcag taaaacgtac cggcagttca ttacgcagca cgcctttttc agtcatcacc
    52801 agaccaacca gtttttctgt gccatgttca cgctgcactt ccagggcttc acgaccgatg
    52861 aagtcacgat ctgccggttc ccaggcgata gtccagccca tgttggcggc taacggagag
    52921 atggtttcgt ccatctcctg accataaaga ttcatgcccg cttccagacg cagcgtgtca
    52981 cgcgcgccca gaccgcatgg cttaacgccc gcttccacca gcgcgcgcca gaaatcggcc
    53041 gctttttcat tgggcagcgc aatttcgtag cccgcttcac cggtgtaacc ggtggtggca
    53101 ataaacagat cgcccgcctg cacgccaaag aacggtttca tcccttccac cgcatgacgc
    53161 tgagcgtcat taaacagtgt ggcagctttt gcctgcgcat tcggcccttg cacggcaatc
    53221 atggaaaggt catcacgaac ggtaatttcg atgccgaaag gttcagcgtg ttgggtaatc
    53281 caggagaggt ctttttcgcg ggtggcggag ttaacaacga ggcggaagaa atcttcagta
    53341 aagtagtaga cgatgaggtc atctatcaca ccgccagagg cattcaacat ccccgagtaa
    53401 agggctttgc cgcttttggt gagtttcgcc acatcgttcg ccagcagata acgcaaaaac
    53461 tcccgggtgc ggctgccgcg aagatcgacg atggtcatat gtgacacatc aaacattccg
    53521 gcatcggtac gtaccgcatg atgttcgtcg atttgcgaac cgtaatgcag cggcatcatc
    53581 cagccgtgga aatccaccat gcgagcgccg caaagcgtgt gttgttcgta caaaggagtc
    53641 tgttgtgcca tcttgtcctc attgaataag cggggctgac aacttttcca tggcgaaatt
    53701 atcaccacga aacccagcat cggagccact cccggtcccc aacgcaatcg ttctcttttg
    53761 cctgaactta ccaccgaaac agactgttaa ccataaggta aaattgatca tcacattagc
    53821 ttatggttaa aaaacgccaa aatcacaaca gaataaaaaa ccaaaaaaca caccaatttc
    53881 tatagaaaga tgatgcgatg aggaaattaa tttgaataag gcaatattaa gagctgaaaa
    53941 aatgtcaaaa aacactaaat caaaaattcg tggcattaga aaatataatg cgaaaacgga
    54001 ggtgaaatta gtttatttca aatgaggaaa atctcccggc gaaaaaaccg ggagatgaaa
    54061 gtgtgatggg tatcaaataa acagcagaag agaaattttt aacgcagcca ttcaggcaaa
    54121 tcgtttaatc ccattgcctg gcggataagt tgtggtttaa cgccaggaag cgtgtcggcc
    54181 agtttcaaac caatatcacg cagcagtttt ttcgccggat tggtaccgga aaacatatcg
    54241 cggaatccct gcataccagc cagcatcagc gccgcactgt gcttgcggct acgctcatag
    54301 cgacgcagat aaatgtactg cccgatgtct ttcccctgac gatgcaaccg tttcagttcg
    54361 gcaatcagct ctgcggcatc cataaagccg agattaacgc cctgccccgc gagcgggtga
    54421 atggtatgcg cggcgtcgcc caccaacgcc agacggtgcg cggcaaattg gcgcgcataa
    54481 cgccccgtca gtgggaacac ctgacgcgca ctctcaacct tgcataagcc aaggcgatta
    54541 tcaaaagcga tatttaacgc gcgattaaat tcgtcttcac ttgcctgctg catccgctgc
    54601 gcttcctctg gcgacagtga ccagacaatc gagcaaagat gcggatcgct aagcggtaaa
    54661 aaggccagaa tgccttcgcc atggaaaacc tgccgcgcca ccgcatcatg cggttcttcc
    54721 gtgcgaatgg tcgctaccag cgcgtgatgc tgataatccc agaaagtcag cggaatatcg
    54781 gctttgttgc gcaaccagga attagcgccg tccgcgccaa tcaccagacg cgccgttaac
    54841 atgctgccat ctttcagcgt caggaaggtt tcattttctc cccaggcgac ctgctgtaat
    54901 tctgcggggg ccaacagagt gatatctgac gactgctgcg ctttgttcca cagcgcgtag
    54961 tgaatcactg agttttcaac gatatgccca agatggctat agcccatgct ttgatcgtca
    55021 aacgaaatgt gaccaaaact gtctttgtcc cacacttcca taccgtgata acaactggcc
    55081 ctacgagaga gaatgtcctg ccagacgcca agacgggtga gtaatttttc gctggcggca
    55141 ttgatagccg aaacgcgcag ttgtggtggt gcatccgccg ccagaggttc cggtacgcgc
    55201 tgctccagta cggcaacgcg taagccgctc ccctgtaagc cgcaggcaac cgccagcccc
    55261 accatgccgc cgccaacaat ggctacatca acactttgca ttgtttattc cttaaaaccg
    55321 ccttcaacgc gccacccaac cgagggtgcg ctgcgccagc acatcgcgtg ccggggtaaa
    55381 taattccatc gtcatcagcc cgatgttgcg cccgacaacc agcggcgtcc aacggttggc
    55441 aaaaagatgt acaaggctgt ccgtgacacc gatggttgct tcgcgatcgc tctgtcgacg
    55501 ctgctgataa cggcacaata cgccgtaatc acctatgtct tctccgcgct cctgcgcctg
    55561 agtcaaggtt tccgcaaggc tcatgacatc ccgcataccg aggttgaacc cttgcccggc
    55621 aatcgggtgc agagtttgcg ccgcattgcc caccagcacg gtacgatggg taataggtct
    55681 ggcggcgcgg gttaacgcca gcggataagc actgcgttta ccagcgtggg taattttccc
    55741 aagtcgccaa ccaaaggccg actggagttc acggcaaaac ttctcgtcgc tccacgacag
    55801 tacctcttcg cgccgttcca gtagatgaca ccagaccagc gaacagcgtc cgtcagacat
    55861 cggcaacatc gccagcgggc catgttgcgt aaagcgttca aaagcgcgcc cttcgtgcgc
    55921 aacggaagtc gcaacgttgg caatcacagc cagttgttcg taaggctcct gctgccagtc
    55981 aacgccgcac acagtggcta acgctgaatg ggtgccatca gcggctacca gcacgcggcc
    56041 cgtcagcgtt tcgccacact ccagcgtcac ttcaacgtga ctctgagtac gggcaacgtt
    56101 agccacgcga tcagggcaat gcagcgttac gccaggtgct ttacgcagca atgcaaacag
    56161 ccgttgcccg acattgtgca attcgacaac ctgtcccagc gccgccagtt ggtaatcttc
    56221 tgcggcgagg gtgacaaatc cagcgtgacc acgatcgctg acatgcacgc tggtgatggc
    56281 ggttgcgcaa tccgccagag attgccaaac gccgatgcgc gccagttgct gacaggtacc
    56341 cgccgccagc gcaatagctc gtccatcaaa gcccggatga gcatgtgact ctggcgcagt
    56401 cgcttcaatc aaatgtaccg gcagcgcccc gtgacttaac cgggaaatag ccagcgccag
    56461 cgtcgcgccc gccatgccgc caccgacgat gattacgctc attgctttct cgcagcagcc
    56521 atcaacgctt cgatttcttc cggctttttc accacgctgg cggtgaggtt ttcgttgccg
    56581 gtttcggtaa tcacaatgtc gtcttcaata cgaatgccga taccgcgata ttgttctggc
    56641 acatccgcat ccggcgcgat atacagacca ggctctacgg tcagtaccat ccccggttcc
    56701 agaatgcgcg agcgatcctg accataaacg ccaacgtcat ggacatccag tcctaaccag
    56761 tggctaaggc catgcataaa gaaaggacga tgggcgttct gagcgatcag ttcatcaaca
    56821 tcacctttca ggatgccgag ttttaccagg ccgctaacca tgatacgcac cacttcacca
    56881 gtgacttcct gcatggaagt tcccggacga tacaggcgca ggctggtttc aagagactcc
    56941 agcacaatgt cgtagatttc acgctgggcc tgagtgaatt tgccgttgac cgggaaggtg
    57001 cgggtaatat cgcccgcgta acctttgtat tcacaacccg cgtcaatcaa caccaggtca
    57061 ccgtcgcgca gttcactctc gttttcggtg tagtgcagaa tgcagccgtt ttcaccgctg
    57121 ccgacgatgg tgttgtagga cggataacgc gcaccgtggc ggttaaattc gtggtgaatt
    57181 tcgccttcca gatggtactc gaacattccc ggacggcatt tttccatcgc ccgggtatgc
    57241 gccagggcgg taatttcccc cgcgcggcga agtacggcaa tctcttccgg cgatttgaac
    57301 aggcgcattt catgaacaat gggacgccag tcgatcatcg ttgccggtgc ggtaagattt
    57361 tgccgcgagc ctttacgcag tttttccagc gcactgttca cgatttcatc agcatatgca
    57421 tattcgccct gggcgtggta aaccacatcc agaccattaa gtagttgata aagttgctga
    57481 ttaatttcgc tgaatgccag agcgcgatca acacccagtt tctctggcgc ggcatcctga
    57541 cctaagcgac gaccaaacca gatctctgcc gtcaggtcgc gaacgcggtt aaacaaaacg
    57601 ctgtggttat gagtgtcatc gcttttaatc agcaccagca ccgcttccgg ttcgttaaag
    57661 ccggtgaagt accagaagtc actgttctga cgataggggt attcgctgtc ggcgctacgt
    57721 gttacttctg gtgcagcaaa aatcagcgcg gcgctgccgg gttgcatttg ctccaccagg
    57781 gcctgacggc gacgctgaaa ctcttgccgg gatatctcac tcataacact ctccttacgt
    57841 tttttgtttt tagtgtagag tcggtttttg tacttctggc gcggtcggtt gcggatgagt
    57901 aaaggtgtcg tggcataaca gcgcggcaac acgaacgtat tcgatgatct cttcaagcga
    57961 catttcaagc tcttcctgat cttcgtcttc gtcgtagccc agctgcgcga tgttacgcag
    58021 atcgtcgatg gcttcaccgg tttcgccggt cactttgtcc agcttcggtt gcgtaacgcc
    58081 aagaccaagc aggaagtgat tgacccaacc tgccagcgca tcagcccgat cgaaaacgct
    58141 gacatcatcg ccatcaggca gataaagctg aaaaaggaag ccgtcatcct gcagggcatc
    58201 gctggtggca gagtgcattt tacgcagtgc ctgtgccagc tcatgaccga aagccatgcc
    58261 ttcgttcgtc aggtcgtgaa gtagcggcag ccatgagctg tcatcgttac cgccacatat
    58321 catcccactg attaaaccat gcatctcagc aggggtcaga cccgtccctt gttggttcag
    58381 atactggttc atttcgttgt aaccaggcat ttcgttctgt atagacataa gcattcgtcg
    58441 tcaaagggag gaatattcat gatatgctac cactttgggc cctggtggac cagaaaaggg
    58501 cttgtctctt ctcatcaggg tagctatagt gtcgcccctt cgcagaccat gggtctaaag
    58561 acgaaggcag cgcagtcaat cagcaggaag gtggcatgtc tgcacaaccc gtcgatatcc
    58621 aaatttttgg ccgttcactg cgtgtgaact gcccgcctga ccaaagggat gcgttgaatc
    58681 aggcagcgga cgatctgaac caacggttgc aagatctgaa agaacgcact agagtcacaa
    58741 atactgaaca gttggtcttc attgccgcat tgaatatcag ctatgagtta gcgcaagaaa
    58801 aagcgaagac tcgtgactac gcggcaagta tggaacagcg tattcggatg ctgcagcaga
    58861 ccatagaaca agcgttactt gaacaaggtc gcatcaccga aaaaactaac caaaactttg
    58921 aatgacactt ttcggtttac tgtggtagag taaccgtgaa gacaaaattt ctctgagatg
    58981 ttcgcaagcg ggccagtccc ctgagccgat atttcatacc acaagaatgt ggcgctccgc
    59041 ggttggtgag catgctcggt ccgtccgaga agccttaaaa ctgcgacgac acattcacct
    59101 tgaaccaagg gttcaagggt tacagcctgc ggcggcatct cggagattcc cttcttatct
    59161 ggcaccagcc atgacgcaac taccagaact cccactgaca ttatcccgac aagaaatccg
    59221 caaaatgatt cggcaacgtc gtcgtgcgtt aacgccggaa caacagcagg aaatgggtca
    59281 acaagctgct acccggatga tgacttatcc cccagtggtg atggcgcata cggtcgctgt
    59341 attcctctct tttgatggcg aactcgacac ccagccactt atagaacaac tctggcgcgc
    59401 cggtaagcgc gtatatcttc cagttttgca tccctttagt gccggtaatt tgctgttcct
    59461 gaattaccat ccgcaaagcg aactggtgat gaacaggttg aagatccatg agccaaaact
    59521 ggatgtgcgt gacgtgctcc ccctttcccg attagacgtg ttgatcacac cgctggtcgc
    59581 ctttgatgag tacggccagc gcctgggaat gggcggtggt ttttatgatc ggaccttaca
    59641 aaactggcag cactataaaa tgcaaccggt gggttatgcg catgattgtc agttggtgga
    59701 aaaactcccc gttgaagagt gggatatccc tcttcctgcg gtggttacac cgtcgaaagt
    59761 ctgggagtgg tgagggcgac acacctgcat cgccctgatt gacatcgttg attctttaac
    59821 ctaatttagt gagtaagggt aagggaggat tactcctccc ctgagactga ctgttaataa
    59881 gctgggaaac ttatgagtaa cagtacaatc agtatgatga caagtcgcat cataaccctt
    59941 ctccttcaag ccctcgcttc ggtgagggct ttaccgttac agccctgtgc tgtcctgcca
    60001 tcgtaaatcc ccattaaata aacacaacgc attgatctga ctttgattta ttttctggag
    60061 cagactcgca aagtagaatg cgcaatgcgg caacggtgtg gaaaagggat aaaaaaacgg
    60121 gcaagtcagt gacctgcccg ttaattttca gagaagggga attagtacag cagacgggcg
    60181 cgaatggtac ccggaatagc tttcattgcc tgcagcgctt tttcggcaac gtcttcgtcg
    60241 gcttcaatat caataaccac ataacccatc tgggcggaag tttgtagata ttgcgcggcg
    60301 atgttgacgc cctgctcggc gaagattttg ttcagcgcag ttagcacgcc cggacggttt
    60361 tcgtggatgt gcatcagacg acgcccaccg tgcagtggca gcgagacttc cgggaagttc
    60421 accgcagaga gcgttgagcc attgtcagaa tacttgatca atttacccgc aacttccagg
    60481 ccgatattct cctgcgcttc ctgagtcgaa ccgccaatgt gtggcgtcag aaggacgttg
    60541 tcgaattcac acagcggaga ggtaaatgga tcgctattgg ttgccggttc cgtcggaaat
    60601 acgtcgattg ccgcccccgc cagatgtttg ctcgccagcg cgtcacacag cgccggaata
    60661 tccaccacag taccgcgcga agcattaatc agcagcgagc cgggcttcat tagtgaaatc
    60721 tctttcgcac ccatcatatt tttggtggac ggattctctg gtacatgcag actcaccaca
    60781 tcgctcatat tcagcaggtc agaaagatgc tgtacctgag tggcgttgcc cagcggcagt
    60841 ttgttttcaa tatcataaaa gtaaacatac attcccagcg attcagccag aatgcccaat
    60901 tgcgtaccaa tatgaccgta gccgatgata cccagctttt tgccgcgcgc ttcaaaagaa
    60961 cccgccgcca gtttgttcca cacgccacgg tgcgctttag cattggcttc cggcacgccg
    61021 cgcaatagca gcagcagttc gccaatcacc agctccgcaa cagagcgcgt atttgagaac
    61081 ggtgcgttaa ataccgggat cccgcgcttt gccgccgcat ccagatcaac ctggtttgtt
    61141 ccgatacaga aacagccaat agcgaccagt ttttctgcgg cgttgatcac gtcttcagtc
    61201 agatgggtac gggatcgcag gccgatgaag tgggcatcgc ggatggattc ttttaattgt
    61261 tcatcatcca gcgcgccttt gtgaaattcg atgttggtgt aaccagctgc acgaaggctt
    61321 tccagcgcct tttggtgcac gccttctacc agcagaaact taatcttgtc tttctccagc
    61381 gatacctttg ccatttaccc aatcctgtct tttgaaatgt tgtgtgcgga tttgcgtccg
    61441 cctttcaaca tatcaaaaaa taatattgcg gcaatatgaa cgtttgcgtc gcgatgttga
    61501 ggaaatatca cgcaaaggta attcttggat gaatatgctg gtttagaaga tttatttaga
    61561 gcaatcgaca atagccaggt aaaaacgtga cacatgtcac caaatttaat gaagagaatt
    61621 tttttaacgg gggaggttcc cccgtcagat catttcacaa tggttttgac accgtcaggt
    61681 gtgccaatca gcgcaacgtc cgcgccacgg ttagcaaaca agccaacagt caccacgcca
    61741 ggaatcgcat ttatggcgtt ttccatcgct atcgggtcaa ggatttccat gccgtggacg
    61801 tcgaggatca cgttgccatt atcggtcacc acgccctgac ggtattccgg acgaccgccc
    61861 agtttcacca gctgacgcgc cactgcacta cgtgccatcg ggataacttc tactggcagc
    61921 gggaatttac ccagaatatc aacctgcttg gaagcgtctg caatacagat aaatttttct
    61981 gcaaccgaag caatgatttt ttcacgggtc agcgccgcgc cgccgccttt gatcatttgc
    62041 atgtggccgt tgatttcatc tgcgccatca acgtagatgc caaggctgtc gacttcgttg
    62101 agatcaaaaa cgtgaatgcc gaggcttttc agtttttcag tggaagcatc tgaactggaa
    62161 acggcccctt caatctggcc tttcattgta ccgagcgcgt caataaagtg tgcggcggtg
    62221 gaacctgtac ctacaccaac aatggtgccg ggctggacat actgaagtgc cgcccatcct
    62281 actgcttttt tcaattcatc ctgcgtcatg atcgtttcgc ctgtggtatg aaatttcaca
    62341 cgcattatat acaaaaaaag cgattcagac cccgttggca agccgcgtgg ttaactcatc
    62401 cataaaatat cgcgcaatgg caggcatccc ctttcgcccc gcaaataagg catgcaacaa
    62461 tctgggtatg ccgctccacg gagcaaacag gcgcaccagt tcaccgttca caagcccctg
    62521 tttacaggca aattgaggca ataacgccac gccattcaac acaaccaggg cgcgaactcg
    62581 ctgagcgaaa tgcattagcg caaatccctg atcttttaag ctgcgcgttt aaccacgaat
    62641 acaaatgtta cccgccgacg gcttcggtat atgcaacctg acacaaaatt gtgtcatagt
    62701 gcaggaaaaa gcatttacca ggagcagaca acagcaatga aacgcccgga ctacagaaca
    62761 ttacaggcac tggatgcggt gatacgtgaa cgaggatttg agcgcgcggc acaaaagctg
    62821 tgcattacac aatcagccgt ctcacagcgc attaagcaac tggaaaatat gttcgggcag
    62881 ccgctgttgg tgcgtaccgt accgccgcgc ccgacggaac aagggcaaaa actgctggca
    62941 ctgctgcgcc aggtggagtt gctggaagaa gagtggctgg gcgatgaaca aaccggttcg
    63001 actccgctgc tgctttcact ggcggtcaac gccgacagtc tggcgacgtg gttgcttcct
    63061 gcactggctc ctgtgttggc tgattcgcct atccgcctca acttgcaggt agaagatgaa
    63121 acccgcactc aggaacgtct gcgccgcggc gaagtggtcg gcgcggtgag tattcaacat
    63181 caggcgctgc cgagttgtct tgtcgataaa cttggtgcgc tcgactatct gttcgtcagc
    63241 tcaaaaccct ttgccgaaaa atatttccct aacggcgtaa cgcgttcggc attactgaaa
    63301 gcgccagtgg tcgcgtttga ccatcttgac gatatgcacc aggccttttt gcagcaaaac
    63361 ttcgatctgc ctccaggcag cgtgccctgc catatcgtta attcttcaga agcgttcgta
    63421 caacttgctc gccagggcac cacctgctgt atgatcccgc acctgcaaat cgagaaagag
    63481 ctggccagcg gtgaactgat tgacttaacg cctgggctat ttcaacgacg gatgctctac
    63541 tggcaccgct ttgctcctga aagccgcatg atgcgtaaag tcactgatgc gttactcgat
    63601 tatggtcaca aagtccttcg tcaggattaa tccatcaaat aatgcctgat agcacatatc
    63661 aggcgttgtc ctcacttctt tttgtattcc ttgaatcaca tcacaaaata gacaaatctc
    63721 aggcggcaaa aaacgacgtc tgaatgcatt ttttttgctg gcgacaaacc cacgtaaaaa
    63781 gctcaccgta ggcgcaaata ccctcatttt gattgcgttt tacggagcaa ataatgtcta
    63841 acgtgcagga gtggcaacag cttgccaaca aggaattgag ccgtcgggag aaaactgtcg
    63901 actcgctggt tcatcaaacc gcggaaggga tcgccatcaa gccgctgtat accgaagccg
    63961 atctcgataa tctggaggtg acaggtaccc ttcctggttt gccgccctac gttcgtggcc
    64021 cgcgtgccac tatgtatacc gcccaaccgt ggaccatccg tcagtatgct ggtttttcaa
    64081 cagcaaaaga gtccaacgct ttttatcgcc gtaacctggc cgccgggcaa aaaggtcttt
    64141 ccgttgcgtt tgaccttgcc acccaccgtg gctacgactc cgataacccg cgcgtggcgg
    64201 gcgacgtcgg caaagcgggc gtcgctatcg acaccgtgga agatatgaaa gtcctgttcg
    64261 accagatccc gctggataaa atgtcggttt cgatgaccat gaatggcgca gtgctaccag
    64321 tactggcgtt ttatatcgtc gccgcagaag agcaaggtgt tacacctgat aaactgaccg
    64381 gcaccattca aaacgatatt ctcaaagagt acctctgccg caacacctat atttacccac
    64441 caaaaccgtc aatgcgcatt atcgccgaca tcatcgcctg gtgttccggc aacatgccgc
    64501 gatttaatac catcagtatc agcggttacc acatgggtga agcgggtgcc aactgcgtgc
    64561 agcaggtagc atttacgctc gctgatggga ttgagtacat caaagcagca atctctgccg
    64621 gactgaaaat tgatgacttc gctcctcgcc tgtcgttctt cttcggcatc ggcatggatc
    64681 tgtttatgaa cgtcgccatg ttgcgtgcgg cacgttattt atggagcgaa gcggtcagtg
    64741 gatttggcgc acaggacccg aaatcactgg cgctgcgtac ccactgccag acctcaggct
    64801 ggagcctgac tgaacaggat ccgtataaca acgttatccg caccaccatt gaagcgctgg
    64861 ctgcgacgct gggcggtact cagtcactgc ataccaacgc ctttgacgaa gcgcttggtt
    64921 tgcctaccga tttctcagca cgcattgccc gcaacaccca gatcatcatc caggaagaat
    64981 cagaactctg ccgcaccgtc gatccactgg ccggatccta ttacattgag tcgctgaccg
    65041 atcaaatcgt caaacaagcc agagctatta tccaacagat cgacgaagcc ggtggcatgg
    65101 cgaaagcgat cgaagcaggt ctgccaaaac gaatgatcga agaggcctca gcgcgcgaac
    65161 agtcgctgat cgaccagggc aagcgtgtca tcgttggtgt caacaagtac aaactggatc
    65221 acgaagacga aaccgatgta cttgagatcg acaacgtgat ggtgcgtaac gagcaaattg
    65281 cttcgctgga acgcattcgc gccacccgtg atgatgccgc cgtaaccgcc gcgttgaacg
    65341 ccctgactca cgccgcacag cataacgaaa acctgctggc tgccgctgtt aatgccgctc
    65401 gcgttcgcgc caccctgggt gaaatttccg atgcgctgga agtcgctttc gaccgttatc
    65461 tggtgccaag ccagtgtgtt accggcgtga ttgcgcaaag ctatcatcag tctgagaaat
    65521 cggcctccga gttcgatgcc attgttgcgc aaacggagca gttccttgcc gacaatggtc
    65581 gtcgcccgcg cattctgatc gctaagatgg gccaggatgg acacgatcgc ggcgcgaaag
    65641 tgatcgccag cgcctattcc gatctcggtt tcgacgtaga tttaagcccg atgttctcta
    65701 cacctgaaga gatcgcccgc ctggccgtag aaaacgacgt tcacgtagtg ggcgcatcct
    65761 cactggctgc cggtcataaa acgctgatcc cggaactggt cgaagcgctg aaaaaatggg
    65821 gacgcgaaga tatctgcgtg gtcgcgggtg gcgtcattcc gccgcaggat tacgccttcc
    65881 tgcaagagcg cggcgtggcg gcgatttatg gtccaggtac acctatgctc gacagtgtgc
    65941 gcgacgtact gaatctgata agccagcatc atgattaatg aagccacgct ggcagaaagt
    66001 attcgccgct tacgtcaggg tgagcgtgcc acactcgccc aggccatgac gctggtggaa
    66061 agccgtcacc cgcgtcatca ggcactaagt acgcagctgc ttgatgccat tatgccgtac
    66121 tgcggtaaca ccctgcgact gggcgttacc ggcacccccg gcgcggggaa aagtaccttt
    66181 cttgaggcct ttggcatgtt gttgattcga gagggattaa aggtcgcggt tattgcggtc
    66241 gatcccagca gcccggtcac tggcggtagc attctcgggg ataaaacccg catgaatgac
    66301 ctggcgcgtg ccgaagcggc gtttattcgc ccggtaccat cctccggtca tctgggcggt
    66361 gccagtcagc gagcgcggga attaatgctg ttatgcgaag cagcgggtta tgacgtagtg
    66421 attgtcgaaa cggttggcgt cgggcagtcg gaaacagaag tcgcccgcat ggtggactgt
    66481 tttatctcgt tgcaaattgc cggtggcggc gatgatctgc agggcattaa aaaagggctg
    66541 atggaagtgg ctgatctgat cgttatcaac aaagacgatg gcgataacca taccaatgtc
    66601 gccattgccc ggcatatgta cgagagtgcc ctgcatattc tgcgacgtaa atacgacgaa
    66661 tggcagccac gggttctgac ttgtagcgca ctggaaaaac gtggaatcga tgagatctgg
    66721 cacgccatca tcgacttcaa aaccgcgcta actgccagtg gtcgtttaca acaagtgcgg
    66781 caacaacaat cggtggaatg gctgcgtaag cagaccgaag aagaagtact gaatcacctg
    66841 ttcgcgaatg aagatttcga tcgctattac cgccagacgc ttttagcggt caaaaacaat
    66901 acgctctcac cgcgcaccgg cctgcggcag ctcagtgaat ttatccagac gcaatatttt
    66961 gattaaagga atttttatgt cttatcagta tgttaacgtt gtcactatca acaaagtggc
    67021 ggtcattgag tttaactatg gccgaaaact taatgcctta agtaaagtct ttattgatga
    67081 tcttatgcag gcgttaagcg atctcaaccg gccggaaatt cgctgtatca ttttgcgcgc
    67141 accgagtgga tccaaagtct tctccgcagg tcacgatatt cacgaactgc cgtctggcgg
    67201 tcgcgatccg ctctcctatg atgatccatt gcgtcaaatc acccgcatga tccaaaaatt
    67261 cccgaaaccg atcatttcga tggtggaagg tagtgtttgg ggtggcgcat ttgaaatgat
    67321 catgagttcc gatctgatca tcgccgccag tacctcaacc ttctcaatga cgcctgtaaa
    67381 cctcggcgtc ccgtataacc tggtcggcat tcacaacctg acccgcgacg cgggcttcca
    67441 cattgtcaaa gagctgattt ttaccgcttc gccaatcacc gcccagcgcg cgctggctgt
    67501 cggcatcctc aaccatgttg tggaagtgga agaactggaa gatttcacct tacaaatggc
    67561 gcaccacatc tctgagaaag cgccgttagc cattgccgtt atcaaagaag agctgcgtgt
    67621 actgggcgaa gcacacacca tgaactccga tgaatttgaa cgtattcagg ggatgcgccg
    67681 cgcggtgtat gacagcgaag attaccagga agggatgaac gctttcctcg aaaaacgtaa
    67741 acctaatttc gttggtcatt aatccctgcg aacgaaggag taaaaatgga aactcagtgg
    67801 acaaggatga ccgccaatga agcggcagaa attatccagc ataacgacat ggtggcattt
    67861 agcggcttta ccccggcggg ttcgccgaaa gccctaccca ccgcgattgc ccgcagagct
    67921 aacgaacagc atgaggccaa aaagccgtat caaattcgcc ttctgacggg tgcgtcaatc
    67981 agcgccgccg ctgacgatgt actttctgac gccgatgctg tttcctggcg tgcgccatat
    68041 caaacatcgt ccggtttacg taaaaagatc aatcagggcg cggtgagttt cgttgacctg
    68101 catttgagcg aagtggcgca aatggtcaat tacggtttct tcggcgacat tgatgttgcc
    68161 gtcattgaag catcggcact ggcaccggat ggtcgagtct ggttaaccag cgggatcggt
    68221 aatgcgccga cctggctgct gcgggcgaag aaagtgatca ttgaactcaa tcactatcac
    68281 gatccgcgcg ttgcagaact ggcggatatt gtgattcctg gcgcgccacc gcggcgcaat
    68341 agcgtgtcga tcttccatgc aatggatcgc gtcggtaccc gctatgtgca aatcgatccg
    68401 aaaaagattg tcgccgtcgt ggaaaccaac ttgcccgacg ccggtaatat gctggataag
    68461 caaaatccca tgtgccagca gattgccgat aacgtggtca cgttcttatt gcaggaaatg
    68521 gcgcatgggc gtattccgcc ggaatttctg ccgctgcaaa gtggcgtggg caatatcaat
    68581 aatgcggtaa tggcgcgtct gggggaaaac ccggtaattc ctccgtttat gatgtattcg
    68641 gaagtgctac aggaatcggt ggtgcattta ctggaaaccg gcaaaatcag cggggccagc
    68701 gcctccagcc tgacaatctc ggccgattcc ctgcgcaaga tttacgacaa tatggattac
    68761 tttgccagcc gcattgtgtt gcgtccgcag gagatttcca ataacccgga aatcatccgt
    68821 cgtctgggcg tcatcgctct gaacgtcggc ctggagtttg atatttacgg gcatgccaac
    68881 tcaacacacg tagccggggt cgatctgatg aacggcatcg gcggcagcgg tgattttgaa
    68941 cgcaacgcgt atctgtcgat ctttatggcc ccgtcgattg ctaaagaagg caagatctca
    69001 accgtcgtgc caatgtgcag ccatgttgat cacagcgaac acagcgtcaa agtgatcatc
    69061 accgaacaag ggatcgccga tctgcgcggt ctttccccgc ttcaacgcgc ccgcactatc
    69121 attgataatt gtgcacatcc tatgtatcgg gattatctgc atcgctatct ggaaaatgcg
    69181 cctggcggac atattcacca cgatcttagc cacgtcttcg acttacaccg taatttaatt
    69241 gcaaccggct cgatgctggg ttaatgactc gtcccgtcac gatcttcagc aatatgctga
    69301 agcatcgtgg cggtataacg atgatttctg attgaataaa gatattcctg catatacatc
    69361 ggcctgtgcg gtgcatcaaa atatttcagc gttgccggat tcaccagtcg ccaggcaaaa
    69421 tgcgggatca ccgtcagaaa atgtccgcgc tccacggcgc tgattttggc cataaaactg
    69481 tagggacgat aaataatggt tggattgatc ccacaaggtc gcatattcgc atcaatcatt
    69541 gcttcgaagt tggcccggtt ctgaaagcgc atttgtagcc agggcagctc ctgaagcagc
    69601 tcttgctctt gtcgctcttc ataacggcga gaaacgagaa agcctaatcg cagcggtggt
    69661 agttcactga tagtcaggtt ttccagttcc tgaactcgtg cagatacatg ctgtggggag
    69721 ataataaaat ctaactggcg gtcaaaaaga ttatcgataa cgccattttc gctgaactca
    69781 actggctggg cggtcacgcc ttcatactta tctccgagac taatcaactg atcgaaaata
    69841 attgtcggat aagtattatc tatgccaatc acaatttctc gtgaacgacg ccctgagtta
    69901 tggatttcat tatcaatcgc agaaagccgt tgataaaccg ggaacagttt ttgatacagt
    69961 tcctgtccgg ctttattgag gctgatatta ttatctttgc gggtaaatag cgtatagcca
    70021 atttgttctt ccagcgcggc aatgctttta ccaaatggcg aagccgtcat atggattttt
    70081 tctgccgccc gggcaatatt attggtttgc gctaataaaa tgaaattgcg catctttttc
    70141 gaaataaaaa tgtccatccc cctcccccgc atccttgtcc gcttaaccgt ttcagtcagc
    70201 ctatccttga tgaaaccgcg agcaaagata ggtgattacg tcatggtttt acagaaaatt
    70261 acagaaaaag gaggcaatat cgggtaaagg cattagcccg acgaatacgt cgggctacaa
    70321 atattattgt gctgcaggtg ttttagcggg ttgttgatcc acaggttcta actggaagac
    70381 cacatcgacc tgatcatcaa actgaatagc ggcctgctcg taagtttcct gggcggacac
    70441 cggcgcggca tcggctttca tcatccgcac cattgggctg ggctgatagt tggaaacatg
    70501 gtagcgcacg ctatataccg gccccagttt acgatgaaag ccgttcgcca gttcctgcgc
    70561 ctgatgaatc gcgttatcaa tcgctgcctt acgcgctttg tctttatagg catccggctg
    70621 cgccacgccc agcgacacag aacgaatttc gttaagaccc gccttcagcg cgccatccag
    70681 caaggaattc agtttgtcta actgacggag cgtgacttcc accgttctca cagcgcggta
    70741 gcctttaagg atacttttac catcctgata atcataatct ggctgggtgc gtaagttcgc
    70801 tgagctgata tcttttttcg cgatctgatt gagttcaagg aaggaaatgt attgtgcgac
    70861 gcgctcatct gcctgtttct tggcagtagc ggcatccttc gcggccacgt taacttcaat
    70921 cgcaagagtg gcaatgtctg gcaccgcatc cacgcttgcc gtaccggagg tgacaatatg
    70981 cggtccatcc ggcaattcgt tagcctgcgc tgccatcccg ctaataccca ttaatgccgc
    71041 cagggcgata actttgaact tcacgttagt ctctccgtgt taattgactt gcccaaaatt
    71101 caggacctct ggaggcaagc ttagcgcctc tgttttattt ttccatcaga tagcgcctaa
    71161 ctgaacaagg cttgtgcatg agcaataccg tctctcgcca gctgcaaggc aataaaccac
    71221 ataacacatc ccacaaccag attgataatg cgctgtgctt ttgccgtgcg cagacgcggt
    71281 gccagccagg ctgcgagaag agccagacca aagaaccaca ggaaagaggc gctaattgtc
    71341 ccgagtgcaa accagcgttt tggttccaca tcaagttgcc cgccaaggct gcccagtaca
    71401 acaaaagtat ccaggtaaac atgcggattc agccaggtca ctgccaacat ggtggcgata
    71461 attttccatc tgccttgctt catgacttcg gcgctggcta actcaatatt actgctcatt
    71521 gctgttttaa aagcgccaaa accataccac agcaagaagg ctacgccgcc ccaggtgacc
    71581 agcgccagca accacggcga ctgcatcaat aacgcgctgc caccaaaaat cccggcgcaa
    71641 atcaggacca aatcgctgat agcacaaagt aaggcaatca taatgtggta ctgacgacgt
    71701 atgccctgat tcatcacaaa agcattttgt ggaccgagcg gtaggatcat agccgcccca
    71761 agtgcaagac cttgaaagta ataagaaaac acgttggata ttccgaatta agtatctgat
    71821 gcagagacta tatcgcggga ttgttattag cggaaattga taatattaat tggcaatcag
    71881 aaaaactaat aagagagagg ccagagagta ttatctggcc tcagcgttga ttacgcagct
    71941 ttgtcttctt tcacccgctt aaagttcaca tccatttgcg ggtacgggaa gctgataccg
    72001 gcggcatcaa attcacgttt aatacgctcc agcacatccc agtacacgtt ttgcagatcg
    72061 ccgctgttgc tccagacgcg gaccacgaaa ttaatcgacg atgcaccaag ttcgttcagg
    72121 cgcacagtca tttcgcgatc tttcaaaatg cgatcttcag actggataat attggtcagg
    72181 atctgcttaa cctgatcgat atcggaatca tacgccacgc caataataaa ttcgttacgg
    72241 cgaactggct cgcgggagaa gttaataata tttccggcaa taattttacc gttcggaata
    72301 acgataattt taccgtctgc agtacgcatg gtggtggaga aaatctgcac actcagcaca
    72361 gtaccggcta cgccgcccag gtcaacatat tctccggcac ggaacgggcg gaacatgaca
    72421 agtaacacgc cagcggccag gttagacagt gacccctgca aagccagacc aacagctaag
    72481 cctgcggcac cgagtacagc aatgactgac gcggtttgta cacccacgcg tcccagtgca
    72541 gcgattagcg taaaggcgat aataccgtaa cggactaatg cagaaagaaa atcagcaaca
    72601 gtggcatcga ttttacggga gatcatcagg cgattcaccg cgttggaaat catccgcgcg
    72661 ataatcaaac caacgatgat gatcgcgagt gccgccacga tgtttactgc ataacttagc
    72721 agcagcgcct ggttagctac cagccagctt cccgcgccgt ttatgctatc gacaacattc
    72781 aaatcttcca ttcaatattc cttttcaact gactcaaaat ggagaaatac actccgccgc
    72841 cttatgacgg gcagtctgac aagggtaaac aataaagcat aattttgcca aatagatcac
    72901 agatttctca tctgaatcac cttgcttttg gcgaaaaaat ccccgcagag cggggctcag
    72961 acagatatca atgtgcgctt tgtcatgccg gatgcggcgt gaacgcctta tccggcctac
    73021 aaaaacctgc aaattcaata tattgcagga tacgtgtagg cctgataagc gtagcgcatc
    73081 aggcaatttt gcttttggcg aaaaaaagac ccgcagagcg ggccttgaga taagcagaaa
    73141 ggaatatctt acagaacgtc gatcgcgttc agttcctgga atgctttctc cagacgagcg
    73201 atcatcgaag tctgaccggc acgcagccat acgcgcggat cgtagtattt cttgttcggc
    73261 tgatcttcgc ctttcgggtt acccagctga ccctgcagat aagcttcgtt cgctttgtag
    73321 tagttcagaa cgccttccca ggttgcccat tgggtatcgg tatcgatgtt catttttact
    73381 acgccgtagc ttacggagtc tttgatttcc tgagcagtag aaccggaacc accgtggaat
    73441 acgaagttca ggctgttgtg cggcaggttg tgtttcttgg aaacatattc ctgagaatca
    73501 cgcaggatgg tcggagtcag aaccacgtta cccggcttgt aaacaccgtg tacgttaccg
    73561 aaggacgctg cgatggtgaa acgcgggctg attttgctca gttcggtgta tgcgtaatca
    73621 acgtcttccg gctgggtgta cagtgcagaa gcgtccatgt ggctgttgtc cacgccgtct
    73681 tcttcaccac cggtgcaacc cagttcgatt tccagagtca tgccgatttt ggacatgcgc
    73741 tccaggtatt tagagcagat ttcgatgttc tcttgcagag attcttcaga caggtcgatc
    73801 atgtgagaag agaacagcgg cttaccggta gctgcgaagt gtttttcacc cgcgtccaac
    73861 agaccgtcga tccacggcag cagtttcttc gcgcagtggt cagtgtgcag gataaccgga
    73921 acaccataat gttcagccat ctggtgaacg tgatgcgcac cagagatcgc gcccaggata
    73981 gcagcaccct gcggaacgtc agatttcacg cctttaccag cgataaagga agcaccaccg
    74041 ttggagaact gaacgataac cggcgcttta actttagcag cggtttccag tacggcgttg
    74101 atggagtcag taccgacgca gtttactgct ggcagtgcga agttgttttc ttttgctacc
    74161 tggaaaactt tctgtacgtc atcaccagtg attacgccag gttttacgaa atcaaaaatc
    74221 ttagacatgt ctcttgtcct gtatcgtcgg gccttatact cgtcatactt caagttgcat
    74281 gtgctgcgtc tgcgttcgct caccccagtc acttacttat gtaagctcct ggggattcac
    74341 tctcttgtcg ccttcctgca actcgaatta tttagagtat gaaaaattgc gtgctctaaa
    74401 agcgcgctga aacaagggca ggtttccctg ccctgtgatt ttttacttct tagcgcgctc
    74461 ttcgagcatc gctactgcag gcagtacttt accttccacg aattcgagga atgcgccgcc
    74521 gccagtggag atgtaggaga ttttgtcagc aatgccgaac aggtcgattg ctgccagagt
    74581 gtcgccgccg ccagcgatgg agaacgcttc gctgtctgcg atagcgttag ccacgatttc
    74641 agtacctttg cggaagttcg ggaattcgaa cacgccaacc ggaccgttcc acagaatggt
    74701 tttcgcattc ttcaggattt cagccagttc ctgagcggaa gcatcaccga tatccaggat
    74761 ctgctcgtca gctttcacat cgttaacaga tttcagggta gccggtgcag tttcagagaa
    74821 ctcggttgct acgcgaacat cagacggaac cgggatgttg caggtggtca gcagacgttt
    74881 agcttcgtca accaggtcag cttcgtacag ggatttaccc acatcgtggc cttgtgccgc
    74941 gataaaggtg ttagcgatac caccaccaac aatcagctgg tcagcgattt tagacaggga
    75001 gtccagaacg gtcagtttgg tagatacttt agaaccacca acgatagcca ccatcgggcg
    75061 agcaggttct ttcagtgctt tacccagcgc gtccagttca gctgccagca gcgggcctgc
    75121 gcacgcaacg tcagcgaatt taccgatacc gtgagtagaa gcctgcgcgc ggtgagcagt
    75181 accgaatgcg tccattacga acacgtcaca cagtgcagcg tattttttgg acagggtttc
    75241 gtcgtctttc ttctcgcctt tgttgaagcg aacgttttcc agaacaacca gttcaccttc
    75301 agcaacgtca acgccgtcga ggtaatcttt aaccagacga accgggttag acagtttgtc
    75361 tttcaggtag ttaacaaccg gcagcagaga gaattcttcg ttgtactcgc cttcggtagg
    75421 acgacccagg tgggaagtta ccatcacttt tgcgccttgt ttcagggcca gttcgatggt
    75481 cggcagagaa gcacggatac gcgcgtcgct ggttactttc ccgtctttta ctggtacgtt
    75541 cagatccgca cggataaata cacgtttccc agcaagatcc agatcggtca tcttaattac
    75601 agacatggtg aatcctctcg ttgattctaa aagttttgca gacgctgctt gcgtcttacc
    75661 tgaaagcaac agtagccata gctaacgtcg tgtcgagcat tcggttagca aagccccatt
    75721 cgttatcgca ccagaccaac gttttgatca ggtgtgcgcc actgacccgg gtttgggtgc
    75781 catcgacaat ggcactgtgc ggatcgtggt taaaatctac agagaccaac ggcaattccg
    75841 tatagtcaac tataccatga aatgcacctt gtgctgcttt ttgcagcaat aggttgactt
    75901 cattggcttt tacaggtttc ttcaccgtca cgcttaaatc gattgccgtc acatttatgg
    75961 ttggcacacg taccgcaatc gcttcaaagc gatcgttaaa ttgcggaaaa aatcgtgtga
    76021 taccggcggc cagtttagta tcgaccggaa tgatcgactg gctggctgcc cgggtgcgac
    76081 gcaggtcagg atggtatgca tcaataacct gttgatcgtg catggcggag tgaattgtgg
    76141 tcacagtgcc ggactcaata ccgtacgcat catctaacaa tttgatgacg ggaattatgc
    76201 aattcgtggt acaggaagcg ttagaaacga tgcggtgttc cgcacgaagt tgatcctgat
    76261 tgacgccgta aacaacggtc gcgtcgagat cgttactgcc aggatgtgaa aagagcactt
    76321 ttttggcccc ggcggcaata tgcgcttcgc catgctcgcg ggagccatat acgccggtgc
    76381 agtcgaggac tacatcaacg ccaagttcac gccaggggag cgattgcagt gaacgttcat
    76441 gcaatacgcg gatggcgtca tcaccaacaa aaagttgatc gcgttcctgt cgtacttccc
    76501 atgcaaaacg gccatggctg gtgtcatatt tcaacaaatg cgccatgccc gcagcatccg
    76561 ccagttcgtt gattgccacc acggtaattt ccgcccggcg tccggattca tacaaagcac
    76621 gaaccacatt acgcccgatg cgaccgaagc catttatcgc tacgcgtacg gtcatagatc
    76681 tcctgcaagg ttttccctga gcaaatttgc cagacagagt aatccagcaa atcgtccggg
    76741 gaaaccttac ctgtcgcaaa ctgcgactga ttggttaatt gtcgaacatt taatcgactg
    76801 aaacgcttca gctaggataa gcgaaacgtg gaataaaagg aatgtttgtc cagccgaaga
    76861 agacatttat ctgactcaca tcacactttt atcccctttt gtgggaagct ttattccagg
    76921 ctggcgtaat aataacccta caataactgg aataaattgt cagcttgtga agtgataccg
    76981 gccttcttca gtcatctcta ctatcagatt ggcctgacgg ctattcatca gcacacgctc
    77041 gacattgggg ccatcggtgc gggcataaaa tgcttcggct acttgccgcg ttaatcctcc
    77101 cgcaatttta cgactaatca agcgctcccg cagaatttga gcaggtgcat gaataaaaat
    77161 agaaaaatcg cagaaagatg ccaactccag ccacttttca tcatccagta acaaccagtt
    77221 tccttcgacg atgacgagtg gtgcggtaac gtgcaacgca tcttcaacag gatcatgctt
    77281 ttgtcgatcg tactgcggcc acgtacaatc cccttccacg acctggcgca gattttccgt
    77341 cagtttcgca acgtcaaatg tctctggtgc gcctttgaag gggcgcaatt gatgcgcatc
    77401 cagccagcta ttgtaatggt gaaaaccatc catcgggagc gtctgaatag cgggcagttc
    77461 cgggtcttgt tgcgcgagat attcccagaa ggtggttagg gttgatttac ccgtccccgg
    77521 cggagcgcaa agaaaaacca ccgtacgccg ctgcggattt accgtctgta aggccgccaa
    77581 catgtgcagc aacggtttat gtacattttc aatctcttcg ttctggtact gtgcctgtat
    77641 cttcagccca ttcaccgtta attcaatttt cacggcgtta attcctttaa ggtggtcgtt
    77701 actgccagcg tcagcgccgt tttgaccatt ccgctaaaac gcgcctctga ccagacggag
    77761 aaatcagcga acttcatcgc ttttaacgcg tcatagagca tcgcattgcg ggttatgcta
    77821 ttgacgttgc tgataaaatc ccaggtcatg tcatcggcaa atccgggcgt ttcatcctgt
    77881 tcgttcaggt aatgccagaa ctgggaaaaa tgcgtgatat cggcgtacaa ccatttatcc
    77941 attttcccca acgcataaat caaacgcagt gcaacatcaa tatcgtcaag cgggccgctt
    78001 tgggcgagta acggcttcac tgcatattcc acgatctctt catcgttatc gacaaacagc
    78061 gacggcagaa actggcgtat cccctggagc aaaatggtat gcgcagtttt cataaatgaa
    78121 aataaattgt cctgtgcatc cagttgctca agcacatcat cttctgtcag cgtcgccatt
    78181 ggtcttccga tagatcacca tcaatgcagg gagtctatta tattacacgt ttggtccgcg
    78241 ccgccgatca gtaatgtctg cgtccgcacc ccattcgccg tctgttggat accgttcacc
    78301 agctcaccgc ccgtcacgcc cgtagcgcta aagaggatat cgttccccct caccagttca
    78361 tcgagcgagt acacacggtt aacgtcaacg cccattgcct tgcaacgctt gcgctcctgc
    78421 tctgcaatct gccgattttc cgtgtaatcc cctttagcct ggcaaaagtc aatcagctcg
    78481 gcctgcatat ccccgcctaa tgctttaacg gcacaggcag aaatcacgcc ttctggcgca
    78541 ccgccgatgg tgtacatcac atcgtaagga ttatcctgcc agcaggtcag cacgctggcg
    78601 gcgacatcgc catccggcag ggcaaaaacc ttcacgccca gctgtgttgc ttcctcaatc
    78661 gcggcactca ggcgcggttt atccagcgta accatgcgca gcttatccag cggtttgcct
    78721 aacgctttcg ccacgttgcg caggttgtcc gtcagaggca aagacagatc aatcgcgccc
    78781 gccgccagcc gattaacaac cagctttttc atatacatat cgggcgcatg taacaggcta
    78841 tctcgagggg cgaaagccat gaccgccagc gcattgctct gccccatcgc caccatccgc
    78901 gtgccttcaa tgggatcaac cgcgatatcg acttctggcc catcgccttt gcccacctct
    78961 tcgccaatcc acagcatcgg cgcatggtca atttctcctt cgccgataac cactcgtcca
    79021 cgaaaagcga cgtcgtttaa tgcctggcgc atcgcggtga ccgccaggcc atcaatttta
    79081 tttttgtcgc cacatccggt ttgcggccag gcagccaacg ctgcctgttc cgtaacgcga
    79141 aataatggcc acgccaggga catcattgcg cggcctcccc gatatcaacg ccaaattgtg
    79201 ccagcagata tttctcggcc tgttcattcc agatgccgtg cgtttcctca accagccgcg
    79261 ccaactcttt aaacagcgga tcggttttgc ctttttcggc aaaatcggca atggcagtga
    79321 gcggcatggt cacgccgtta taaatgagtt ttttaccgcc agggatatcc ggcagattga
    79381 gcacggtttc tggcaccgca tccaggccac cgatatgggt caccataaac gacggctgta
    79441 actgcccagt ggcgctaagg gcaatcgcct ctttcatgtc gtccgttgaa ccgccagatg
    79501 taccgacgac gtgcgtgctg ttgtaatgga cgttgtagaa attaaacggc actttgaagt
    79561 ttttatccgt cggcccggca aagaagttca gacagccatc ttccgccagt aattcatcag
    79621 ccatctcaac gacagcaggc accgccgcat aaacaaaaat gtcatcgaac ccggcatctc
    79681 ctgtcagcgc ccgcagcatc tggacaggat cgctcatccc tttggtattc acatacacca
    79741 gctcaatgcc tttactggcc gccagttcca ccggcagcag cttctgtacc tgcgccagac
    79801 gtttgtcgtc gatatcgacc accaccaccc gcgacggttg tatgccgccg ttaatggcgt
    79861 aatcgatagc gccaatgccc atcggacctg cacacgccag cagtgcaata ttgccgccag
    79921 gtttgacgcc catgcgatgc tcataaacat attgcgtggt gtgataattg gcatgataag
    79981 caccaataat gcagcacata ggctctgcca gcgacgccgc agcaaaataa gagccgtgat
    80041 acggtaatac gcagcccaaa ttaatggcga tttcgggaat aatcatataa gtggcattgc
    80101 cgccaaaata ttcgtagctg tagcccgctg aatatccgct tggtaacccc atcgccggtt
    80161 gcaatacaaa acgctggcct tttttatatt tgccagtgag atttttaccc acttcgacaa
    80221 taaccccggc acattcatgc ccggtaatga ccggatgatt ttctaaatcg tcgggtacgc
    80281 gtttatgttc actaccgagt aacgccgctt tccaggtcga taaacagacg ctgtcagaaa
    80341 ttacactcac cagtaattca ttatcggtaa tttctggcag ttcaaatacg cgcagacgga
    80401 catcccgctt gccataaata gcagcaactt tggttttcat ttttacctct gtaatcagtg
    80461 tttatgttcg gcggttaatt gattaaataa agtgtcgagt tttggatcgc caatatagtt
    80521 attaatcaat atcagtggtt tatccgtcac acgtttcacg cgcccttcca gactggcatg
    80581 agtaacgacg atatccgcat ccgcaggcac gttttctatg gcgtaatgtt ttacttcaat
    80641 tgccagcccc gctttttcca ggcgtttacg gaaggtggtc gcgcccatcg cactggagcc
    80701 catccccgca tcgcaaacaa aggcgatacg cttaaccctg cttaacgaga atgcaccctc
    80761 ttgtttcatc gccttaaccg cattggctga ctgagcaaac tcatcttcgc tctccgtttc
    80821 caccgttttt tccatcttca gtatcagcga agtaatagca aaggacacca gggtacctac
    80881 cgtaacaccg gcaattgtcg ccaggaacga gcctttcggc gtcagtgcca ggtaagcaaa
    80941 gatagacccc ggacttgggc cagccaccag accaccgtcc agtaagttaa acatccaggt
    81001 gccagacata ccgcccgcaa tcatggcaat aatggtcagc ggcttcatca gcacatacgg
    81061 gaaatacagt tcgtggatcc caccgaggaa gtgaataatc atcgccccgg gcgcagaacg
    81121 tttactcatc cctttaccaa acaaggtaaa cgccagcagc agccccaggc ccggacctgg
    81181 gttagaggcc accataaaga agatggattt accgttaacc gaagcctgtt gcattcccag
    81241 cggataatag acgccctgat cgatcgcatt attgaggaaa agcactttcg ccggttcatt
    81301 gatgactgac aacaatggca gataacccgc atgtaccagc gcctcaatac actctttgac
    81361 gaaagtattg gcaattaaca ccgccgggcc gataacttca aaacccagca gacaaaggag
    81421 catccccgcg atacctaatg agaagttatt gataaccatc tcaaaaccgg caggtatgcg
    81481 tttttccagt gccttatcga catattttat gaccaaccca ccgagcggcc ccatgatcat
    81541 tgagccaagg aacatcggga tctctgcgcc aacgatcaca ccaatagtat ctattccgcc
    81601 catgaccgcc ccgcgtttac cgccgaccag atgaccacct gtagaaccaa tcatcacggg
    81661 caataaatag gtaatcatcg ggccgacaat tttggcgaaa tgttcgttag gcagccaacc
    81721 ggtgggaata aataacgcag taataaaacc ccaggcaata aaagcaccaa tattggggat
    81781 gaccattgca gtcaaaaagc ccccaaaagc ctggaccttt gcacgagcag acttgttttc
    81841 cataatatta tcctgtagag gagagagtaa ttatccgcgg ctgataatgt ccgctaatta
    81901 tttttctgat gatgctgtta agagttgttc gagtatttct tcttcgcaca gtaattcact
    81961 taacgcctga atagcgccaa tgtgcgaatc ggcatcggca gcagagagtc cgatgagtaa
    82021 tttaattggt tcgtcattcc ccggaaaata aacaccttgt tcaagtaatg tcaaagacat
    82081 cccggtttta agcgccccac attccggtcg cgcatgaggc attgccacgc ctggtgcgag
    82141 aatataataa gggccattgt taatggtgga atctttaatt gcctgaatgt aattctcgct
    82201 gatatagttt ttatccagca atgataccat cgagaaatcg atagcttcct gccaatcttt
    82261 tgctgaatgt ataactgaga ttgatgattc tggaaaataa tcactaagcc gcataaatta
    82321 tccttatttt atttttaggg taccgtccgg cggtaaaaat aaaatactcg tgcggtttaa
    82381 tgaaagcaat tgagcaggga aaccggtgtt ttgaaaacag tgaattatta atttcttata
    82441 taacattgag ttatagatat aacaacaaat gtcaatacgc atatcgtgat gcatattaca
    82501 taattgatat ttattgcata taaatatttg tgatctacaa gacgccttat ctattgcttg
    82561 tccgcaaacg gacatatcaa ggtaataaaa aaggtcgccg aagcgacctt tttacccgaa
    82621 atgctaatta cagcagttct tttgctttcg caacaacgtt atcaacagtg aagccgaact
    82681 cttcaaacag cagctctgcc ggagcagatt caccgaaggt ggtcataccg acgatagcac
    82741 cgttcaggcc aacatacttg taccagtagt cagcaatacc cgcttctaca gcaacgcgtg
    82801 cagtaaccgc tttcggcagt acggattcac ggtaagcagc atcctgcttg tcaaatgcgt
    82861 cggtagacgg catggacacc acgcgcgctt tcacgccttc ggcagtcagt ttttcgtagg
    82921 cagcaacagc cagttcaact tctgaaccgg tagcgatgaa aatcagttcc ggctgaccgg
    82981 cgcagtcttt cagcacataa ccaccgcgcg cgatgtttgc cagttgctct tcagttcgtt
    83041 cctgctgcgc caggttctga cgggagagga tcagtgcggt cgggccgtcc tgacgctcaa
    83101 caccgtattt ccacgcgacc gcggattcaa cctggtcaca cggacgccat gtagacatgt
    83161 tcggggttac gcgcagagaa gcgacctgct caaccggctg gtgagtcggg ccgtcttcgc
    83221 ccagaccgat ggagtcgtgg gtgtaaacca tcacctgacg ctgtttcatc agcgcagcca
    83281 tacgtacggc gttacgtgcg tattccacga acatcaggaa ggtggaggtg tacggcagga
    83341 agccaccgtg cagggagata ccgttagcaa tcgcggtcat accgaactcg cgaacaccgt
    83401 agtggatgta gttacccgca gcatcttcgt tgattgcttt agaaccagac cacagggtca
    83461 ggttagacgg cgccaggtca gcagaaccgc cgaggaattc cggcaacagc ggaccgaacg
    83521 cttcgatagc attctgagac gctttacggc tggcgatttt cgccggatta gcctgcagtt
    83581 tagcgatgaa ctctttcgct ttagcgtcga agtcagacgg catttcgcct ttcatacggc
    83641 gggtaaattc agcggcttcc tgcggataag ctttcgcgta agcagcgaat ttctcgttcc
    83701 atgcggattc tttcgcctgg cctgcttctt tcgcatccca ctgagcatag atttcagacg
    83761 ggatttcgaa cggcgcatat ttccagccca gttgttcgcg ggtcagggca atttcagcgt
    83821 cgcccagcgg cgcaccgtgg gagtcgtggg taccggcttt gttcggggaa ccgaaaccga
    83881 tgatggtttt gcacatcagc agggaaggtt tgtcagtcac tgcgcgcgct tcttctactg
    83941 cgcgtttgat agatgccgcg tcatgaccgt cgatgtcgcg aataacgtgc cagccgtaag
    84001 cttcgaaacg cattgcggtg tcgtcggtga accagccttc aacgtgacca tcgatagaaa
    84061 taccgttgtc atcgtagaat gcaatcagtt tacccagctt cagcgtaccc gccagagagc
    84121 aaacttcgtg ggagatgcct tccatcatgc agccgtcgcc catgaaggcg taggtgtagt
    84181 ggtcgacaat gtcgtggccc ggacggttaa actgcgccgc cagcgttttt tctgcaatcg
    84241 ccataccgac tgcgttggca ataccctgac ccagcggacc ggtggtggtt tccacaccag
    84301 cggtgtaacc cacttccggg tgacccggag ttttagagtg cagctgacgg aagtttttca
    84361 gttcttccat cggcagatcg taaccggtga ggtgcagcag gctgtagatc agcatggagc
    84421 cgtggccgtt ggacagcacg aagcggtcac ggtcagccca ggacggattc tgcgggttgt
    84481 gtttcaggaa atcacgccac aggacttcgg caatgtcagc catacccata ggggcacccg
    84541 ggtgaccgga tttggctttc tgtactgcgt ccatgctcag cgcacgaata gcattggcaa
    84601 gctctttacg tgaggacatt ttgactccag atcggatgat gaagggcacg cccttaacga
    84661 cttgacgaca gcgcgttttg ggctacgccg gaaaatttgc caacaattta ccgcaagccg
    84721 cgcgtcatgt acatggaaca tccttttgcc gcttcagaaa tctctggatc atgctcgcat
    84781 gttgcgcaat ctactcgccc gtccgctgcg cttttcctta tactgagact gagcgtcgat
    84841 tcacctgcaa acggcgcatt tttagaataa tcctgacctt gtgcggaaga gaaaacatga
    84901 aaattcgcgc cttattggta gcaatgagcg tggcaacggt actgaccggt tgccagaata
    84961 tggactccaa cggactgctc tcatcaggag cggaagcttt tcaggcttac agtttgagtg
    85021 atgcgcaggt gaaagccctg agcgatcagg catgtcagga gatggacagc aaggcgacga
    85081 ttgcgccagc caatagcgaa tacgctaaac gtctgacaac tattgccaat gcgctaggca
    85141 acaatatcaa cggtcagccg gtaaattaca aagtgtatat ggcgaaggat gtgaacgcct
    85201 ttgcaatggc taacggctgt atccgtgtct atagcgggct gatggatatg atgacggata
    85261 acgaagtcga agcggtgatc ggtcacgaaa tggggcacgt ggcgttaggc catgtgaaaa
    85321 aaggaatgca ggtggcactt ggtacaaatg ccgtgcgagt agctgcggcc tctgcgggcg
    85381 ggattgtcgg aagtttatct caatcacaac ttggtaatct gggcgagaaa ttagtcaatt
    85441 cgcaattctc ccagcgccag gaagcagaag ccgatgatta ttcttacgat cttctgcgcc
    85501 aacgcggcat cagcccggca ggtcttgcca ccagctttga aaaactggca aaactggaag
    85561 aaggtcgcca aagctcaatg tttgacgacc atcctgcatc cgccgaacgc gcccagcata
    85621 ttcgcgatcg catgagcgcg gatgggatta agtaaagcct ggtggtgtcg aacgtaggtc
    85681 agataaggcg ttcacgccgc atctgacatg aatggcacat ttgttacctt gtgcgcattg
    85741 ccggatgcga tgctggcgca tcttatccgg cctacgggtg ccgaacgtag gtcggataag
    85801 gcgttcacgc cgcatccgac attaatggca cgttttaccc gtgcgcatcg catctggtgc
    85861 ttactcgccc tttttcgccg cctgaatata cagcatttcc agcgccagcg ttgccgctgc
    85921 cagagcagtg atttccgact gatcgtatgc cggagccact tccactacgt ccatcccaac
    85981 aatgttgaga tctttcaggc cgcgtaccag tttaatagcg cgatcggagg tcaggccgcc
    86041 aatcactggc gtaccggtgc ctggtgcaaa agcaggatcc aggcagtcga tatcaaaagt
    86101 caggtaaacc ggcatatcac ccacaatctg tttcacttgg gcgataacgt catccacgct
    86161 gcgatcgttc acctggcagg cgtccagcac ggtaaagccg ttgtctttat caaactcggt
    86221 acgaatacca atctgcacgg aatgattcgg gtcgatcaga ccttctttcg gcgcggtata
    86281 gaacatagtg ccgtggtcaa attcacaacc gttcgcatag gtatcggtgt gggcgtcaaa
    86341 gtgtaccagc gccattttgc cgaaatgctt cgcatgagca cgcagcagcg gcagcgtaac
    86401 aaagtggtca ccaccgaaag agagcatacg cttaccggca gccagcagct tctcggcgtg
    86461 cgcctgcagc ttttcgctca tctcacgggc atcgccaaag gcatatacca gatcgccgca
    86521 gtccacgacg ttcagacgct cacgcatgtc gaaattccac gggaagcggt tgtgttccca
    86581 ggccagattc gtcgaaacct gacggatcgc tgccggaccg tggcgaccac ccgcacgacc
    86641 agaagtggcc atatcgaacg gcacgccagt aatcacccag tctgcatcgc tgtcatacgg
    86701 ctggaagttc atcggcaggc gtaaaaaacc aaaggcattg gaaaccagtg agttatcgta
    86761 ttgatgacct aaggtgctca tggatggact cctattacaa agtcgatata aaaaaaccct
    86821 tccgcgtcgt taggcccgac gaggaagggt tggatttgtc acaataaatt gtggcggatt
    86881 atcaccgcta aattaagcgg attcaagtaa cacaggactt actcatcttc aagataagta
    86941 taaccgtaca aacctgcctc gaactcttca aggaactgtt gttgcagttc agcatcaaga
    87001 tcggttttct tcacttgatc gcggaactgg gttaacagcg ttttcggatc gagctgtaca
    87061 tattgcagca tgtccgccac ggtatcgcct tcgtcagaca gttctacttc tacgctaccg
    87121 tcagggaaga cgaacacgtc aaccgcttcg gtatcaccga acaggttgtg catgttgccg
    87181 aggatctcct gatatgcgcc gaccataaag aaaccgagca tcggcggatt ctctggatcg
    87241 tactccggca ttggcattgt cgtggcaata ccgtcaccat caatatagtg gtcgatagca
    87301 ccgtcagagt cacaggtaat atccagcagc acagcgcgac gttccggcac ttgatccagc
    87361 ccttccagcg gcagaaccgg gaacaactgg tcgatccccc atgcgtccgg catcgactgg
    87421 aacagcgaga agttgacgta cattttgtcc gccatacgtt cctgcagctc gtcgataatc
    87481 ggacgatgag cacggttttg cggatccagc tgcttttgca cttcatggca catgctcaaa
    87541 taaagctgct cagcccatgc acgttcttgc aggctaaaga tgccggaaga gtagccgata
    87601 tgaatgtcgt gcagatccat ctgactgtcg tgtaaccatt cacgcagaga acggcgagtt
    87661 cccggttcgt gcatctcctg ccaggtttcc cacatgcttt gcagcgcgcg cggcgcatct
    87721 tctgcaggcg cggtcggcac cgtgtattcg ttacgttcca cgccgatgat attagacacc
    87781 agcacggtgt gatgcgcagt caccgcacga cccgattcgg tgattaccgt cggatgcggc
    87841 agaccgtttt cttcacacgc atcgccaatc gcccagataa tgttgttggc gtattcattg
    87901 aggccgtagt tcaccgaaca gtcggactgc gaacgagtac cttcataatc cacgcccaga
    87961 ccgccgccga cgtcgaagca ctgaatattg acgcccagct tgtgcagttc cacatagaaa
    88021 cgcgcggatt cacgaacgcc tgtcgcgata tcgcgaatat tcgccatctg cgaaccgagg
    88081 tggaagtgca gtagttgcag gctgtcgaga cgcccggctt cacgcagggt ttcaaccagt
    88141 tgcagtacct gagtcgcagc caggccgaac ttcgattttt ccccgccgga ggactgccat
    88201 ttacccgaac cctgcgaagc cagacgtgca cgcacgccca gacgaggaac gacattcaga
    88261 cgttctgctt catccagcac aatggcgatt tctgacatct tctcaatgac cagatagacc
    88321 ttgtgcccca tcttctcgcc aattaatgcc aggcggatat attcgcggtc tttataaccg
    88381 ttgcagacga tgacgctacg ggtcatgcca gcatgtgcca gtactgccat caactcggct
    88441 ttggaaccgg cttccagacc cagcggttcg cccgaatgaa tcagggactc aatcacgcgg
    88501 cggtgctggt taactttgat cggataaaca aggaagtaat cgccgttata gccgtaggat
    88561 tccctcgcac gtttgaacgc ggcgttaatg gaacgcaaac ggtgctgcag gatctgtggg
    88621 aaacagaaca gtgcaggcag acgctggccc tgtgcttcac gagttttcac taactgcgcg
    88681 agatcgacgc gagcttccgg gacgtccggg tccgggcaca cgctaatgtg gcccagctcg
    88741 ttaacgtcat agtagttatt gccccaccag gcaatattgt aagtacgcag catcttgctg
    88801 gcttcctggg agctcattgc aacctcctgc atggagcgta gtacaccgtg ttcgcccgct
    88861 gacgaaggca aacccataga catgtcgtca gacatagcga acctcaaatt attttattaa
    88921 gtgtaaaaca gttaacgact atcgcagcct ggaactgcga taacaaccca taagcacatg
    88981 gattttccag cagtgaatgc tgacgctcca actgcgcaac cggtttcttt ttcataacat
    89041 tattaagcac ataaccgaac gtaagtgtga aagttcggcg aaaccacgag aaaactcttg
    89101 tttttacaag agcgcccttg ttcagtcctc agtaactgta accagctctt gaatcctgag
    89161 aagcgccgag atgggtataa catcggcagg tatgcaaagc agagatgcag agtgcgggga
    89221 acgaatcttc accagaacgg tgagacaggt taagcagcag acaacggttc attatttcgt
    89281 atcacctcca cggccgcctg ttaagacgaa cccacaagcc aaaactctga tttcaacccg
    89341 gctggaagtg gcaacacgaa agaaacgtcg tgtgcttttt atttaagccg cgcgccgcgt
    89401 tttatacccc acaatggcag aaaattgcaa aagataaata cgcagaatgc cggcattgtc
    89461 aggaaaaatt tccagccacg tttttaacag aatgagacac gattcaaaaa aaagtggaaa
    89521 tagggtgaag aattgaccta aaatagccat ccagatgtta atccatccat accgattaac
    89581 actcagactg ccagtgtttt taacctgcag agtcgtggta ggatccgcta ccacagaaaa
    89641 tccacacaac agtttgagct aaccaaattc tctttaggtg atattaaata tggcaaaaca
    89701 cctttttacg tccgagtccg tctctgaagg gcatcctgac aaaattgctg accaaatttc
    89761 tgatgccgtt ttagacgcga tcctcgaaca ggatccgaaa gcacgcgttg cttgcgaaac
    89821 ctacgtaaaa accggcatgg ttttagttgg cggcgaaatc accaccagcg cctgggtaga
    89881 catcgaagag atcacccgta acaccgttcg cgaaattggc tatgtgcatt ccgacatggg
    89941 ctttgacgct aactcctgtg cggttctgag cgctatcggc aaacagtctc ctgacatcaa
    90001 ccagggcgtt gaccgtgccg atccgctgga acagggcgcg ggtgaccagg gtctgatgtt
    90061 tggctacgca actaatgaaa ccgacgtgct gatgccagca cctatcacct atgcacaccg
    90121 tctggtacag cgtcaggctg aagtgcgtaa aaacggcact ctgccgtggc tgcgcccgga
    90181 cgcgaaaagc caggtgactt ttcagtatga cgacggcaaa atcgttggta tcgatgctgt
    90241 cgtgctttcc actcagcact ctgaagagat cgaccagaaa tcgctgcaag aagcggtaat
    90301 ggaagagatc atcaagccaa ttctgcccgc tgaatggctg acttctgcca ccaaattctt
    90361 catcaacccg accggtcgtt tcgttatcgg tggcccaatg ggtgactgcg gtctgactgg
    90421 tcgtaaaatt atcgttgata cctacggcgg catggcgcgt cacggtggcg gtgcattctc
    90481 tggtaaagat ccatcaaaag tggaccgttc cgcagcctac gcagcacgtt atgtcgcgaa
    90541 aaacatcgtt gctgctggcc tggccgatcg ttgtgaaatt caggtttcct acgcaatcgg
    90601 cgtggctgaa ccgacctcca tcatggtaga aactttcggt actgagaaag tgccttctga
    90661 acaactgacc ctgctggtac gtgagttctt cgacctgcgc ccatacggtc tgattcagat
    90721 gctggatctg ctgcacccga tctacaaaga aaccgcagca tacggtcact ttggtcgtga
    90781 acatttcccg tgggaaaaaa ccgacaaagc gcagctgctg cgcgatgctg ccggtctgaa
    90841 gtaatctttc ttcacctgcg ttcaaaggcc agcctcgcgc tggccttttt cttttggata
    90901 ggcgttcacg ccgcatccgg caaaaaaaac cgcccgcaca ataacatcat tcttcctgat
    90961 cacgtttcac cgcagattat catcacaact gaaaccgatt acaccaacca caacagacaa
    91021 agatttgtaa tattttcata ttattattcg gttttcacag ttgttacatt tcttttcagt
    91081 aaagtcttaa ttgcagataa cagcgtttaa tctatgatga tataactcaa ttattttcat
    91141 gcacttaaat cataa
//
LOCUS       DACAOP010000004        88223 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.004, whole genome shotgun sequence.
ACCESSION   DACAOP010000004 DACAOP010000000
VERSION     DACAOP010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 88223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88223
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.004"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..434
                     /locus_tag="IT892_000268"
     CDS             <1..434
                     /locus_tag="IT892_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133521.1"
                     /translation="RLAIIESIPRATLTDELENELTKEIYKSSSKINNYLSRIKLPEM
                     KAFSLEKIDYYIDIIIKDYESVKENAYLIVPKINYNTDLNIEDSSSEEFLPDNTIEKD
                     ENSPDNCFEVVKYNTYEAYNSEKQYYTREDYTYDYDLLNAI"
     gene            complement(825..1201)
                     /gene="rnpB"
                     /locus_tag="IT892_000269"
     ncRNA           complement(825..1201)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IT892_000269"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            complement(1234..2379)
                     /gene="garK"
                     /locus_tag="IT892_000270"
     CDS             complement(1234..2379)
                     /gene="garK"
                     /locus_tag="IT892_000270"
                     /EC_number="2.7.1.165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312029.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 2-kinase"
                     /protein_id="HAP3133522.1"
                     /translation="MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADG
                     GEGTVEAMIAATQGSERHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAE
                     KRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
                     IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAM
                     IVELDNNLSHYADVIKKALHVDVKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTAL
                     NLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYNKPVIGIAGSLTNDVGVVH
                     QHGIDAVFSVLTSIGTLDEAFRGAYDNIYRASRNIAATLAIGMRNAG"
     gene            complement(2476..3366)
                     /gene="garR"
                     /locus_tag="IT892_000271"
     CDS             complement(2476..3366)
                     /gene="garR"
                     /locus_tag="IT892_000271"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HAP3133523.1"
                     /translation="MTMKVGFFGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAA
                     GAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLA
                     SREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVV
                     HTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD
                     AKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQAVRADGLGT
                     ADHSALACYYEKLAKVEVTR"
     gene            complement(3396..4166)
                     /gene="garL"
                     /locus_tag="IT892_000272"
     CDS             complement(3396..4166)
                     /gene="garL"
                     /locus_tag="IT892_000272"
                     /EC_number="4.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyglucarate aldolase"
                     /protein_id="HAP3133524.1"
                     /translation="MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWL
                     VLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVET
                     KEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDN
                     VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAP
                     VEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK"
     gene            complement(4182..5516)
                     /locus_tag="IT892_000273"
     CDS             complement(4182..5516)
                     /locus_tag="IT892_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3133525.1"
                     /translation="MILDTVDVKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEV
                     AKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGF
                     VDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
                     LALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISE
                     NGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIY
                     LVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLL
                     ASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGN
                     VASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK"
     gene            5891..7462
                     /gene="garD"
                     /locus_tag="IT892_000274"
     CDS             5891..7462
                     /gene="garD"
                     /locus_tag="IT892_000274"
                     /EC_number="4.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate dehydratase"
                     /protein_id="HAP3133526.1"
                     /translation="MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLE
                     LIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTL
                     PLATKVPAPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL
                     LPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKL
                     QPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQVAERHLHKLNQRQRET
                     CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP
                     RAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGK
                     SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVP
                     VIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW
                     GLHNQLAVFNPAPVT"
     gene            7611..7946
                     /gene="prlF"
                     /locus_tag="IT892_000275"
     CDS             7611..7946
                     /gene="prlF"
                     /locus_tag="IT892_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PrlF"
                     /protein_id="HAP3133527.1"
                     /translation="MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHY
                     EILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFNIQQGKKLVAGMDVN
                     IDDEIGDDE"
     gene            7946..8410
                     /locus_tag="IT892_000276"
     CDS             7946..8410
                     /locus_tag="IT892_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YhaV family
                     toxin"
                     /protein_id="HAP3133528.1"
                     /translation="MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKA
                     ATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKNKDWSRVKFGAGRYRLFFRYSEK
                     EKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWETLTRETEEPH"
     gene            complement(8465..9274)
                     /gene="agaR"
                     /locus_tag="IT892_000277"
     CDS             complement(8465..9274)
                     /gene="agaR"
                     /locus_tag="IT892_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aga operon transcriptional regulator AgaR"
                     /protein_id="HAP3133529.1"
                     /translation="MSNTDASGEKRMTGTSERREQIIQRLRQQGSVQVNDLSALYGVS
                     TVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVE
                     LIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
                     RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERII
                     VVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE"
     gene            9523..10803
                     /gene="kbaZ"
                     /locus_tag="IT892_000278"
     CDS             9523..10803
                     /gene="kbaZ"
                     /locus_tag="IT892_000278"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaZ"
                     /protein_id="HAP3133530.1"
                     /translation="MKHLTEMVRQHKEGKTNGIYAVCSAHPLVLEAAIRYASANQTPL
                     LIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQSLPA
                     AQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCL
                     EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWS
                     RIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLV
                     IDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLENVMLDRPEYWQSH
                     YHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQY
                     VKVRSGKLQPTPRELIINHIQDILAQYHTACEGQ"
     gene            10826..11299
                     /gene="agaV"
                     /locus_tag="IT892_000279"
     CDS             10826..11299
                     /gene="agaV"
                     /locus_tag="IT892_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312038.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HAP3133531.1"
                     /translation="MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQ
                     QNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKILLVCKTPADFLTLVKGGVPVNRI
                     NVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKAAGVECFVQGVPTEPAVDLFKLL"
     gene            11310..12089
                     /locus_tag="IT892_000280"
     CDS             11310..12089
                     /locus_tag="IT892_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HAP3133532.1"
                     /translation="MEISLLQAFALGIIAFIAGLDMFNGLTHMHRPVVLGPLVGLVLG
                     DLHTGILTGGTLELVWMGLAPLAGAQPPNVIIGTIVGTAFAITTGVKPDVAVGVAVPF
                     AVAVQMGITFLFSVMSGVMSRCDRMAENADTRGIERVNYLALLALGTFYFLCAFLPIY
                     FGAEHAKTIIDVLPQRLIDGLGVAGGIMPAIGFAVLLKIMMKNVYIPYFILGFVAAAW
                     LKLPVLAIAAAALAMALIDLLRKSPEPTQPAAQKEEFEDGI"
     gene            12079..12957
                     /locus_tag="IT892_000281"
     CDS             12079..12957
                     /locus_tag="IT892_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019079236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAP3133533.1"
                     /translation="MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRV
                     AWRSMLLQASFNYERMQASGWLYGLLPALKKIHTNKRDLARAMKGHMGFFNTHPFLVT
                     FVIGIILAMERSKQDVNSIQSTKIAVGAPLGGIGDAMFWLTLLPICGGIGASLALQGS
                     ILGAVVFIVLFNVVHLGLRFGLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGA
                     LVATYVRLSTTLEITAGDAVVKLQADVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLI
                     AITVVLGIVGKFCHFL"
     gene            12975..13409
                     /locus_tag="IT892_000282"
     CDS             12975..13409
                     /locus_tag="IT892_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP3133534.1"
                     /translation="MLSIILTGHGGFASGMEKAMKQILGEQSQFIAIDFPETSSTALL
                     TSQLEEAIAQLDCEDGIVFLTDLLGGTPFRVASTLAMQKPGCEVITGTNLQLLLEMVL
                     EREGLSGEEFRVQALECGHRGLTSLVDELGRCHEECPVEEGI"
     gene            13406..14539
                     /gene="nagA"
                     /locus_tag="IT892_000283"
     CDS             13406..14539
                     /gene="nagA"
                     /locus_tag="IT892_000283"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAP3133535.1"
                     /translation="MTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDA
                     ELLCPAYIDTHVHGGAGVDVMDDAPDVLDKLAMHKAREGVGSWLPTTVTAPLNTIHAA
                     LKRIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHT
                     LRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMT
                     GLHHREPGMVGAGLTDKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGM
                     PDGRYTLCGEEVQMHGGVVRTASGGLAGSTLSVDAAVRNMVELTDVTPAEAIHMASLH
                     PARMLGVDDVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF"
     gene            14890..16044
                     /locus_tag="IT892_000284"
     CDS             14890..16044
                     /locus_tag="IT892_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AgaS family sugar isomerase"
                     /protein_id="HAP3133536.1"
                     /translation="MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALRSALNNF
                     LEPLLRKENLRVILTGAGTSAFIGDIIAPWLASHTDKNFSAVPTTDLVTNPMDYLNPA
                     HPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALL
                     MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQSFRDVADRCQAILTSLGDFSEGV
                     FGYAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDNET
                     LVVVFVSSHPYTRQYDLDLLAELRRDNQAMRVIAIAAESNDVITAGPHIILPPSRHFI
                     DVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA"
     gene            16057..16917
                     /gene="kbaY"
                     /locus_tag="IT892_000285"
     CDS             16057..16917
                     /gene="kbaY"
                     /locus_tag="IT892_000285"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaY"
                     /protein_id="HAP3133537.1"
                     /translation="MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSP
                     VILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAM
                     IDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEA
                     KRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFV
                     RRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKIN
                     VCGSANRISA"
     gene            17084..17560
                     /gene="agaB"
                     /locus_tag="IT892_000286"
     CDS             17084..17560
                     /gene="agaB"
                     /locus_tag="IT892_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HAP3133538.1"
                     /translation="MSSPNILLTRIDNRLVHGQVGVTWTSTIGANLLVVVDDVVANDD
                     IQQKLMGITAETYGFGIRFFTIEKTINVIGKAAPHQKIFLICRTPQTVRKLVEGGIDL
                     KDVNVGNMHFSEGKKQISSKVYVDDQDLTDLRFIKQRGVNVFIQDVPGDQKEQIPD"
     gene            17599..18402
                     /locus_tag="IT892_000287"
     CDS             17599..18402
                     /locus_tag="IT892_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylgalactosamine permease IIC component 1"
                     /protein_id="HAP3133539.1"
                     /translation="MHEITLLQGLSLAALVFVLGIDFWLEALFLFRPIIVCTLTGAIL
                     GDIQTGLITGGLTELAFAGLTPAGGVQPPNPIMAGLMTTVIAWSTGVDAKTAIGLGLP
                     FSLLMQYVILFFYSAFSLFMTKADKCAKEADTAAFSRLNWTTMLIVASAYAVIAFLCT
                     YLAQGAMQALVKAMPAWLTHGFEVAGGILPAVGFGLLLRVMFKAQYIPYLIAGFLFVC
                     YIQVSNLLPVAVLGAGFAVYEFFNAKSRQQAQPQPVASKNEEEDYSNGI"
     gene            18392..19183
                     /gene="agaD"
                     /locus_tag="IT892_000288"
     CDS             18392..19183
                     /gene="agaD"
                     /locus_tag="IT892_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708938.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IID"
                     /protein_id="HAP3133540.1"
                     /translation="MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKK
                     IYKDDKPGLSAAMKDNLEFINTHPNLVGFLMGLLISMEEKGENRDTIKGLKVALFGPI
                     AGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGV
                     KAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDSTHSVALQQDFFDK
                     VFPNILPMAYTLLMYYFLRVKKAHPVLLIGVTFVLSIVCSAFGIL"
     gene            19184..19951
                     /locus_tag="IT892_000289"
     CDS             19184..19951
                     /locus_tag="IT892_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosamine-6-phosphate isomerase"
                     /protein_id="HAP3133541.1"
                     /translation="MERGTASGGASLLKEFHPVQTLQQVENYMALSERASEYLLAVIR
                     SKPDAVICLATGATPLLTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETF
                     LQQHIVQPLGLREDQLISFRSEEINETECERVTHLIARKGGLDLCVLGLGKNGHLGLN
                     EPGESLQPACHISQLDARTQQHEMLKTAGRPVTRGITLGLKDILNAREVLLLVTGEGK
                     QDATERFLTAKVSTAIPASFLWLHNYFTCMIDEMCRR"
     gene            complement(20001..20864)
                     /gene="rsmI"
                     /locus_tag="IT892_000290"
     CDS             complement(20001..20864)
                     /gene="rsmI"
                     /locus_tag="IT892_000290"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAP3133542.1"
                     /translation="MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAE
                     DTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPG
                     YHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
                     AEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVK
                     EDENRRKGEMVLIVEGHKAQEDDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNA
                     LYKYALEQQGE"
     gene            20929..22965
                     /locus_tag="IT892_000291"
     CDS             20929..22965
                     /locus_tag="IT892_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708948.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator"
                     /protein_id="HAP3133543.1"
                     /translation="MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQ
                     ADSAFYLQQMQQSSDDTRINWQLLAIRALVKEDKTGQAVELFNQLPQELNDSQRREKT
                     LLAAEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIA
                     QEPLLGAKEKQQNIDATWQTLSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDP
                     DMMKAGIADWQKRYPNNPGAKILPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTI
                     QQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQ
                     PVPVSAPAATTAAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNV
                     EELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIP
                     RSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGSPITPRATT
                     DSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATL
                     YASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMG
                     VDAWSLANHFSQMRQVQGFEINGNTGSLTANPDCVINRKLSWLQYQQGQVVPAS"
     gene            22923..23318
                     /locus_tag="IT892_000292"
     CDS             22923..23318
                     /locus_tag="IT892_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HAP3133544.1"
                     /translation="MATVPTRSSSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVN
                     ERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGS
                     FDTVDCRFDVVAFTGNEVEWIKDAFNDHS"
     gene            23338..23928
                     /gene="diaA"
                     /locus_tag="IT892_000293"
     CDS             23338..23928
                     /gene="diaA"
                     /locus_tag="IT892_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001483830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA initiator-associating protein DiaA"
                     /protein_id="HAP3133545.1"
                     /translation="MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKI
                     LCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQ
                     VRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
                     IRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDV"
     gene            23938..24513
                     /gene="yraP"
                     /locus_tag="IT892_000294"
     CDS             23938..24513
                     /gene="yraP"
                     /locus_tag="IT892_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divisome-associated lipoprotein YraP"
                     /protein_id="HAP3133546.1"
                     /translation="MKALSPIAVLLSALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQ
                     VDDGTLEVRVNSALSKDEQIKKEARINVTAYQGKVLLVGQSPNAELSARAKQIAMGVD
                     GANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMG
                     LVTEREAKAAADIASRVSGVKRVTTAFTFIK"
     gene            complement(24626..25666)
                     /locus_tag="IT892_000295"
     CDS             complement(24626..25666)
                     /locus_tag="IT892_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAP3133547.1"
                     /translation="MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWQPYYGKAFTA
                     AETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLR
                     TLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPLLNPAT
                     LVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFS
                     RWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGAVDNSLMWVIAMAVAGCLFVI
                     PTAAEIPIVQTMMLAGMGIAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAV
                     SGVIVGGLALLV"
     gene            complement(25739..26374)
                     /locus_tag="IT892_000296"
     CDS             complement(25739..26374)
                     /locus_tag="IT892_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312060.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HAP3133548.1"
                     /translation="MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGV
                     FNPHDPQLTDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLG
                     AQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
                     TLFAPLFRLLPGNWKSIDARDVARVMLAEAMRPEHEGVTILSSSELRKRAE"
     gene            26502..27020
                     /gene="yhbO"
                     /locus_tag="IT892_000297"
     CDS             26502..27020
                     /gene="yhbO"
                     /locus_tag="IT892_000297"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein/nucleic acid deglycase"
                     /protein_id="HAP3133549.1"
                     /translation="MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVK
                     GKKGEASVAIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFA
                     ICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
                     AFNREALRLLGS"
     gene            complement(27000..27443)
                     /locus_tag="IT892_000298"
     CDS             complement(27000..27443)
                     /locus_tag="IT892_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbP family protein"
                     /protein_id="HAP3133550.1"
                     /translation="METLTAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFY
                     ILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGMQFKGEIRRLEGEESDLARQAYN
                     RRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRNSGTEQA"
     gene            27493..27795
                     /gene="yhbQ"
                     /locus_tag="IT892_000299"
     CDS             27493..27795
                     /gene="yhbQ"
                     /locus_tag="IT892_000299"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708956.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage response exodeoxyribonuclease YhbQ"
                     /protein_id="HAP3133551.1"
                     /translation="MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKG
                     ELTLAFSAPVGDRSLALRAEYRVKKLTKRQKERLVAEGAGFAELLSSLQTPEIKSD"
     gene            complement(27782..28285)
                     /locus_tag="IT892_000300"
     CDS             complement(27782..28285)
                     /locus_tag="IT892_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP3133552.1"
                     /translation="MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGL
                     VATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNE
                     FGYAAVVTLGDPALYSRFGFELAAHHDLRCCWPGTESAFQVHRLADDALNGVTGLVEY
                     HEHFNRF"
     gene            complement(28279..28803)
                     /locus_tag="IT892_000301"
     CDS             complement(28279..28803)
                     /locus_tag="IT892_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HAP3133553.1"
                     /translation="MLDKLRSRIVHLGPSLLSVPVKLTPFALKRQVLEQVLSWQFRQA
                     LDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVVSQNAQADVSFSADASDLLMIAA
                     RKQDPDTLFFQRRLAIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMK
                     TAPETKQTSVGEPC"
     gene            29012..30007
                     /locus_tag="IT892_000302"
     CDS             29012..30007
                     /locus_tag="IT892_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017457364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP3133554.1"
                     /translation="MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTE
                     KKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRAVDMAAQLGADALILADLAMLEY
                     AAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPVPL
                     EVFAFGSLCIMSEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNEVLID
                     RYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQR
                     SPAYVSQVAKVWRQAIDRCKADPQNFIPQSAWMETLGSMSEGTQTTLGAYHRKWQ"
     gene            30016..30894
                     /locus_tag="IT892_000303"
     CDS             30016..30894
                     /locus_tag="IT892_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417628.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP3133555.1"
                     /translation="MKYSLGPVLWYWPKETLEEFYQQAATSSADVIYLGEAVCSKRRA
                     TKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGELKRYVENGEFLIEASDLGVVNM
                     CAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRN
                     QFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLN
                     GIQTMSGYVYNLGNELTSMQGLVDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANS
                     DCNGYWRRLAGLELQA"
     gene            30975..31982
                     /locus_tag="IT892_000304"
     CDS             30975..31982
                     /locus_tag="IT892_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HAP3133556.1"
                     /translation="MTDKTIPFSLLDLAPIPEGSSAREAFSHSLDLARLAEKRGYHRY
                     WLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLY
                     PGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPG
                     YGEKIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKP
                     YAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGV
                     QQALSMSLVGDKAKVRHGLQSILRETDADEIMVNGQIFDHQARLHSFELAMDVKEELL
                     G"
     gene            complement(32100..33344)
                     /gene="mtr"
                     /locus_tag="IT892_000305"
     CDS             complement(32100..33344)
                     /gene="mtr"
                     /locus_tag="IT892_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan permease"
                     /protein_id="HAP3133557.1"
                     /translation="MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWS
                     MAALIFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYIL
                     TYAYISASGSILHHTFAEMSLNVPARAAGFGFALLVAFVVWLSTKAVSRMTAIVLGAK
                     VITFFLTFGSLLGHVQPATLFNVAESNASYAPYLLMTLPFCLASFGYHGNVPSLMKYY
                     GKDPKTIVKCLVYGTLMALALYTIWLLATMGNIPRPEFIGIAEKGGNIDVLVQALSGV
                     LNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSAMGRLKTALLTFAPPV
                     VGGLLFPNGFLYAIGYAGLAATIWAAIVPALLARASRKRFGSPKFRVWGGKPMIALIL
                     IFGVGNALVHILSSFNLLPVYQ"
     gene            complement(33498..35387)
                     /locus_tag="IT892_000306"
     CDS             complement(33498..35387)
                     /locus_tag="IT892_000306"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH family ATP-dependent RNA helicase"
                     /protein_id="HAP3133558.1"
                     /translation="MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGR
                     DVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMR
                     GVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
                     MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRP
                     DISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALN
                     GDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIG
                     RTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQ
                     QQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKR
                     EFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAI
                     ANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPH
                     TGGERRGGGRGFGGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRR
                     FGGDA"
     gene            complement(35380..35460)
                     /gene="yrbN"
                     /locus_tag="IT892_000307"
     CDS             complement(35380..35460)
                     /gene="yrbN"
                     /locus_tag="IT892_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrbN"
                     /protein_id="HAP3133559.1"
                     /translation="MKIADQFHDELCRLAAINFEAHVLHG"
     gene            complement(35567..36451)
                     /gene="nlpI"
                     /locus_tag="IT892_000308"
     CDS             complement(35567..36451)
                     /gene="nlpI"
                     /locus_tag="IT892_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpI"
                     /protein_id="HAP3133560.1"
                     /translation="MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVIL
                     ARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYL
                     GIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
                     PNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMER
                     LKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALL
                     ELSLLGQDQDDLAESDQQ"
     gene            complement(36560..38695)
                     /gene="pnp"
                     /locus_tag="IT892_000309"
     CDS             complement(36560..38695)
                     /gene="pnp"
                     /locus_tag="IT892_000309"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAP3133561.1"
                     /translation="MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTV
                     VGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPL
                     FPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
                     YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQN
                     INELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSE
                     TIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVL
                     PRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGM
                     VGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
                     MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMD
                     IKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIK
                     DVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRV
                     YNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQ
                     GRIRLSIKEATEQSQPAAAPEAPAAEQGE"
     gene            complement(38942..39211)
                     /gene="rpsO"
                     /locus_tag="IT892_000310"
     CDS             complement(38942..39211)
                     /gene="rpsO"
                     /locus_tag="IT892_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAP3133562.1"
                     /translation="MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFA
                     EHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR"
     gene            complement(39360..40304)
                     /gene="truB"
                     /locus_tag="IT892_000311"
     CDS             complement(39360..40304)
                     /gene="truB"
                     /locus_tag="IT892_000311"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAP3133563.1"
                     /translation="MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHT
                     GALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVT
                     FDTEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLF
                     IRHEGNELELEVHCSKGTYIRTIIDDLGEKLDCGAHVIYLRRLAVSKYPVERMVTLEH
                     LRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAP
                     LEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA"
     gene            complement(40304..40705)
                     /gene="rbfA"
                     /locus_tag="IT892_000312"
     CDS             complement(40304..40705)
                     /gene="rbfA"
                     /locus_tag="IT892_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAP3133564.1"
                     /translation="MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMS
                     RDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNS
                     LVEGMRMSNLVTSVVKHDEERRVNPDDSKED"
     gene            complement(40864..43536)
                     /gene="infB"
                     /locus_tag="IT892_000313"
     CDS             complement(40864..43536)
                     /gene="infB"
                     /locus_tag="IT892_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAP3133565.1"
                     /translation="MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQT
                     LIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERL
                     AAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSN
                     QQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDN
                     AEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADRE
                     EARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIK
                     AMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAP
                     VVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAA
                     FTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPD
                     RVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMAS
                     GAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSI
                     PVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMT
                     EGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASN
                     AILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLA
                     EVRDVFKSPKFGSIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVR
                     NGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA"
     gene            complement(43561..45048)
                     /gene="nusA"
                     /locus_tag="IT892_000314"
     CDS             complement(43561..45048)
                     /gene="nusA"
                     /locus_tag="IT892_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAP3133566.1"
                     /translation="MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEID
                     VRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESVTF
                     DRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEA
                     VILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGE
                     EVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLW
                     DDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGW
                     ELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKEL
                     LEIEGLDEPTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGIDRDLAFKLAA
                     RGVCTLEDLAEQGIDDLADIEGLTDEKAGALIMAARNICWFGDEA"
     gene            complement(45076..45528)
                     /gene="rimP"
                     /locus_tag="IT892_000315"
     CDS             complement(45076..45528)
                     /gene="rimP"
                     /locus_tag="IT892_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAP3133567.1"
                     /translation="MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSED
                     GINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLV
                     LRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF"
     gene            complement(45735..45811)
                     /locus_tag="IT892_000316"
     tRNA            complement(45735..45811)
                     /locus_tag="IT892_000316"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45775..45777),aa:Met,seq:cat)
     gene            46159..47502
                     /gene="argG"
                     /locus_tag="IT892_000317"
     CDS             46159..47502
                     /gene="argG"
                     /locus_tag="IT892_000317"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HAP3133568.1"
                     /translation="MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTAN
                     LGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNT
                     TPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDT
                     DFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVN
                     PIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMS
                     DQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQG
                     RWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKG
                     DSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ"
     gene            complement(47510..49135)
                     /locus_tag="IT892_000318"
     CDS             complement(47510..49135)
                     /locus_tag="IT892_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417641.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HAP3133569.1"
                     /translation="MTVFNKFVRSFKSHWLLYLCVIVFGITNLVASSGAHMVQRLLFF
                     VLTILVVKRISSLPLRLLVAAPFVLLTAADMSISLYSWCTFGTTFNDGFAISVLQSDP
                     DEVVKMLGMYIPYLCAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQ
                     FAYKDAKNKKAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVR
                     DTGIDTYVLIVGESVRVDNMSLYGYTRSTTPQVEAQRKQIKLFNQAISGAPYTALSVP
                     LSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETV
                     YVRGFDELLLPHLSQALQQKTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDAC
                     YDNSIHYTDSLLGQIFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHV
                     PMFIWYSPVLGDGVDRTTENDIFSTAYNNYLINAWMGVTKPEQPKTLEEVIAHYKGDS
                     RVVDANHDVFDYVMLRKEFTEDKQGNPTPEGQG"
     gene            complement(49592..49678)
                     /locus_tag="IT892_000319"
     tRNA            complement(49592..49678)
                     /locus_tag="IT892_000319"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(49642..49644),aa:Leu,seq:gag)
     gene            complement(49693..50025)
                     /gene="secG"
                     /locus_tag="IT892_000320"
     CDS             complement(49693..50025)
                     /gene="secG"
                     /locus_tag="IT892_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAP3133570.1"
                     /translation="MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFAAGASATLFG
                     SSGSGNFMTRMTALLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPA
                     KPTSDIPN"
     gene            complement(50253..51590)
                     /gene="glmM"
                     /locus_tag="IT892_000321"
     CDS             complement(50253..51590)
                     /gene="glmM"
                     /locus_tag="IT892_000321"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003905541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAP3133571.1"
                     /translation="MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRK
                     IIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISAS
                     HNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
                     FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVG
                     ATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQL
                     RGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLD
                     KTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVK
                     AVTAEVEAALGSRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV"
     gene            complement(51583..52431)
                     /gene="folP"
                     /locus_tag="IT892_000322"
     CDS             complement(51583..52431)
                     /gene="folP"
                     /locus_tag="IT892_000322"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312083.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HAP3133572.1"
                     /translation="MKLYAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHA
                     NLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIPVVEAIAQRFEVWISVDTSKPEV
                     IRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGM
                     SRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAK
                     ENKRYE"
     gene            complement(52521..54455)
                     /gene="ftsH"
                     /locus_tag="IT892_000323"
     CDS             complement(52521..54455)
                     /gene="ftsH"
                     /locus_tag="IT892_000323"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAP3133573.1"
                     /translation="MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNND
                     QVREARINGREINVTKKDSNRYTTYIPVQDPKLLDNLLTKNVKVVGEPPEEPSLLASI
                     FISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA
                     KEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISG
                     SDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLN
                     QMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVH
                     MRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKI
                     MMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLP
                     EGDAISASRQKLESQISTLYGGRLAEEIIYGPEHVSTGASNDIKVATNLARNMVTQWG
                     FSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQLLTD
                     NMDILHAMKDALMKYETIDAPQIDDLMARRDVRPPAGWEEPGASNNSGDNGSPKAPRP
                     VDEPRTPNPGNTMSEQLGDK"
     gene            complement(54555..55184)
                     /gene="rlmE"
                     /locus_tag="IT892_000324"
     CDS             complement(54555..55184)
                     /gene="rlmE"
                     /locus_tag="IT892_000324"
                     /EC_number="2.1.1.166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uridine(2552)-2'-O)-methyltransferase
                     RlmE"
                     /protein_id="HAP3133574.1"
                     /translation="MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQ
                     SDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRD
                     ELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGS
                     FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP"
     gene            55310..55603
                     /gene="yhbY"
                     /locus_tag="IT892_000325"
     CDS             55310..55603
                     /gene="yhbY"
                     /locus_tag="IT892_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAP3133575.1"
                     /translation="MNLSTKQKQHLKGLAHPLKPVVLLGSNGLTEGVLAEIEQALEHH
                     ELIKVKIATEDRETKTLIVEAIVRETGACNVQVIGKTLVLYRPTKERKISLPR"
     gene            complement(55759..56235)
                     /gene="greA"
                     /locus_tag="IT892_000326"
     CDS             complement(55759..56235)
                     /gene="greA"
                     /locus_tag="IT892_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006178768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAP3133576.1"
                     /translation="MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKE
                     NAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDSDEE
                     QTYRIVGDDEADFKQNLISVNSPIARGLIGKEEDDVVVIKTPGGEVEFEVIKVEYL"
     gene            56483..57916
                     /gene="dacB"
                     /locus_tag="IT892_000327"
     CDS             56483..57916
                     /gene="dacB"
                     /locus_tag="IT892_000327"
                     /EC_number="3.4.16.4"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001212660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HAP3133577.1"
                     /translation="MRFSRFIIGLTSCIAFSVQAANVDEYITQLPAGANLALMVQKVG
                     ASAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVENGVLKGDLV
                     ARFGADPTLKRQDIRNMVATLKKSGVNQIDGNVLIDTSIFASHDKAPGWPWNDMTQCF
                     SAPPAAAIVDRNCFSVSLYSAPKPGDMAFIRVASYYPVTMFSQVRTLPRGSAEAQYCE
                     LDVVPGDLNRFTLTGCLPQRSEPLPLAFAVQDGASYAGAILKDELKQAGITWSGTLLR
                     QTQVNEPGTVVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHARFNVPGTWRAGSD
                     AVRQILRQQAGVDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPL
                     AGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAV
                     EPADQRNRRIPLVRFESRLYKDIYQNN"
     gene            complement(57956..59128)
                     /gene="cgtA"
                     /locus_tag="IT892_000328"
     CDS             complement(57956..59128)
                     /gene="cgtA"
                     /locus_tag="IT892_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Obg family GTPase CgtA"
                     /protein_id="HAP3133578.1"
                     /translation="MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGD
                     VWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTG
                     ETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLA
                     DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLI
                     EGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAK
                     PRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIE
                     NPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR"
     gene            complement(59144..60109)
                     /locus_tag="IT892_000329"
     CDS             complement(59144..60109)
                     /locus_tag="IT892_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012135318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HAP3133579.1"
                     /translation="MKQQAGIGILLALTTAICWGALPIAMKQVLEVMEPPTIVFYRFL
                     MASIGLGAILAVKKRLPPLRVFRKPRWLILLAVATAGLFGNFILFSSSLQYLSPTASQ
                     VIGQLSPVGMMVASVFILKEKMRSTQVVGALMLLSGLVMFFNTSLVEIFTKLTDYTWG
                     VIFGVGAATVWVSYGVAQKVLLRRLASPQILFLLYTLCTIALFPLAKPGVIAQLSHWQ
                     LACLIFCGLNTLVGYGALAEAMARWQAAQVSAIITLTPLFTLFFSDLLSLAWPDFFAR
                     PMLNLLGYLGAFVVVAGAMYSAIGHRIWGGLRKHTTVVSQPRAGE"
     gene            complement(60236..60493)
                     /gene="rpmA"
                     /locus_tag="IT892_000330"
     CDS             complement(60236..60493)
                     /gene="rpmA"
                     /locus_tag="IT892_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007369914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAP3133580.1"
                     /translation="MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTK
                     FHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE"
     gene            complement(60514..60825)
                     /gene="rplU"
                     /locus_tag="IT892_000331"
     CDS             complement(60514..60825)
                     /gene="rplU"
                     /locus_tag="IT892_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAP3133581.1"
                     /translation="MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANG
                     EEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGIS
                     A"
     gene            61084..62055
                     /gene="ispB"
                     /locus_tag="IT892_000332"
     CDS             61084..62055
                     /gene="ispB"
                     /locus_tag="IT892_000332"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HAP3133582.1"
                     /translation="MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGG
                     KRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA
                     FGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
                     ENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNA
                     DGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMN
                     ACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQRDR"
     gene            62283..62561
                     /gene="sfsB"
                     /locus_tag="IT892_000333"
     CDS             62283..62561
                     /gene="sfsB"
                     /locus_tag="IT892_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SfsB"
                     /protein_id="HAP3133583.1"
                     /translation="MESNFIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALSR
                     PWPKGEMIIAKALGTDPWIIWPSRYHDPQTHEFIDRTQLMRSYTKPKK"
     gene            complement(62609..63868)
                     /gene="murA"
                     /locus_tag="IT892_000334"
     CDS             complement(62609..63868)
                     /gene="murA"
                     /locus_tag="IT892_000334"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP3133584.1"
                     /translation="MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNV
                     PKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVA
                     RFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK
                     VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGV
                     ERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVG
                     EDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMH
                     VPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRI
                     YHIDRGYERIEDKLRALGANIERVKGE"
     gene            complement(63923..64177)
                     /gene="ibaG"
                     /locus_tag="IT892_000335"
     CDS             complement(63923..64177)
                     /gene="ibaG"
                     /locus_tag="IT892_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015585657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family iron metabolism protein IbaG"
                     /protein_id="HAP3133585.1"
                     /translation="MENNEIQSVLMNALSLQEVHVSGDGSHFQVIAVGELFDGMSRVK
                     KQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF"
     gene            complement(64337..64630)
                     /gene="mlaB"
                     /locus_tag="IT892_000336"
     CDS             complement(64337..64630)
                     /gene="mlaB"
                     /locus_tag="IT892_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HAP3133586.1"
                     /translation="MSESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDL
                     SRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDKVYTLAKLYNLPADVLPR"
     gene            complement(64630..65265)
                     /gene="mlaC"
                     /locus_tag="IT892_000337"
     CDS             complement(64630..65265)
                     /gene="mlaC"
                     /locus_tag="IT892_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HAP3133587.1"
                     /translation="MFKRLMMVALLVIAPLSAATAADQTNPYKLMDEAAQKTFDRLKN
                     EQPQIRANPDYLRTIVDQELLPYVQVKYAGALVLGQYYKSATPAQREAYFAAFREYLK
                     QAYGQALAMYHGQTYQIAPEQPLGDKTIVPIRVTIIDPNGRPPVRLDFQWRKNSQTGN
                     WQAYDMIAEGVSMITTKQNEWGTLLRTKGIDGLTAQLKSISQQKITLEEKK"
     gene            complement(65284..65835)
                     /gene="mlaD"
                     /locus_tag="IT892_000338"
     CDS             complement(65284..65835)
                     /gene="mlaD"
                     /locus_tag="IT892_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HAP3133588.1"
                     /translation="MQTKKNEIWVGIFLLAALLAALFVCLKAANVTSIRTEPTYTLYA
                     TFDNIGGLKARSPVSIGGVVVGRVADITLDPKTYLPRVTLEIEQRYNHIPDTSSLSIR
                     TSGLLGEQYLALNVGFEDPELGTAILKDGDTIQDTKSAMVLEDLIGQFLYGSKGDDNK
                     NSGDAPAAAPGNNETTEPVGTTK"
     gene            complement(65840..66622)
                     /gene="mlaE"
                     /locus_tag="IT892_000339"
     CDS             complement(65840..66622)
                     /gene="mlaE"
                     /locus_tag="IT892_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014071945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HAP3133589.1"
                     /translation="MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLL
                     VRQLYNVGVLSMLIIVVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPV
                     VAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTV
                     IFVAVGIWGGSLVGVSWKGIDSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISL
                     FNGYDAIPTSAGISRATTRTVVHSSLAVLGLDFVLTALMFGN"
     gene            complement(66630..67439)
                     /gene="mlaF"
                     /locus_tag="IT892_000340"
     CDS             complement(66630..67439)
                     /gene="mlaF"
                     /locus_tag="IT892_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid ABC transporter ATP-binding protein
                     MlaF"
                     /protein_id="HAP3133590.1"
                     /translation="MEQSVANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSG
                     IGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNV
                     FDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
                     LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWIL
                     ADKKIVAHGSAQALQANPDPRVRQFLDGIADGPVPFRYPAGDYHADLLPGS"
     gene            67649..68626
                     /locus_tag="IT892_000341"
     CDS             67649..68626
                     /locus_tag="IT892_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HAP3133591.1"
                     /translation="MLLATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTV
                     VSIGTSLPEIIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLR
                     RELPLMLLVSVVAGSVLYDGQLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTR
                     EQLAELPRDGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAI
                     GTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAYSRDY
                     SVMLLVSIIFALLCWRRSPQSGRGVGVLLTGGFIVWLAMLYWLSPILVE"
     gene            68640..69626
                     /gene="kdsD"
                     /locus_tag="IT892_000342"
     CDS             68640..69626
                     /gene="kdsD"
                     /locus_tag="IT892_000342"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase KdsD"
                     /protein_id="HAP3133592.1"
                     /translation="MSHVELQPGFDFQQAGKEVLAIERECLAELDQYINQNFTLACEK
                     MFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFFVHPGEAAHGDLGMVTPQDVVIA
                     ISNSGESSEITALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVAKEACPLGLAP
                     TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPH
                     VKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMGVDVRQLSIADV
                     MTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLRAGVV"
     gene            69647..70213
                     /gene="kdsC"
                     /locus_tag="IT892_000343"
     CDS             69647..70213
                     /gene="kdsC"
                     /locus_tag="IT892_000343"
                     /EC_number="3.1.3.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate-8-phosphatase KdsC"
                     /protein_id="HAP3133593.1"
                     /translation="MSKAGASLATCYGPVSADVIAKAENIRLLILDVDGVLSDGLIYM
                     GNNGEELKAFNVRDGYGIRCALTSDIEVAIITGRKAKLVEDRCATLGITHLYQGQSNK
                     LIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTRIA
                     GGRGAVREVCDLLLLAQGKLDEAKGQSI"
     gene            70210..70785
                     /gene="lptC"
                     /locus_tag="IT892_000344"
     CDS             70210..70785
                     /gene="lptC"
                     /locus_tag="IT892_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HAP3133594.1"
                     /translation="MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKS
                     EHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAK
                     LTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
                     LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP"
     gene            70754..71311
                     /gene="lptA"
                     /locus_tag="IT892_000345"
     CDS             70754..71311
                     /gene="lptA"
                     /locus_tag="IT892_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide ABC transporter
                     substrate-binding protein LptA"
                     /protein_id="HAP3133595.1"
                     /translation="MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQS
                     LDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGKEVIDGYGKPATFYQMQDNG
                     KPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
                     TTVLVPSQLQDKNNKGQTPAQKKGN"
     gene            71318..72043
                     /gene="lptB"
                     /locus_tag="IT892_000346"
     CDS             71318..72043
                     /gene="lptB"
                     /locus_tag="IT892_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004091254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HAP3133596.1"
                     /translation="MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT
                     TFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAV
                     LQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL
                     LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAH
                     GTPTEILQDEHVKRVYLGEDFRL"
     gene            72091..73524
                     /gene="rpoN"
                     /locus_tag="IT892_000347"
     CDS             72091..73524
                     /gene="rpoN"
                     /locus_tag="IT892_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAP3133597.1"
                     /translation="MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALESN
                     PLLEQIDTHEEIDTRETQDSETLDTADALEQKEMPEELPLDASWDTIYTAGTPSGTSG
                     DYIDDELPVYQGETTQTLQDYLMWQVELTPFSDTDRAIATSIVDAVDETGYLTVPLED
                     ILESIGDEEIDIDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKTTPWLEEARL
                     IISDHLDLLANHDFRTLMRVTRLKEDVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDV
                     LVRKHNGHWTVELNSDSIPRLQINQHYASMCNNARNDGDSQFIRSNLQDAKWLIKSLE
                     SRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
                     PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQG
                     IMVARRTVAKYRESLSIPPSNQRKQLV"
     gene            73547..73834
                     /gene="hpf"
                     /locus_tag="IT892_000348"
     CDS             73547..73834
                     /gene="hpf"
                     /locus_tag="IT892_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007369896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation promoting factor"
                     /protein_id="HAP3133598.1"
                     /translation="MQLNITGNNVEITEALREFVTAKFAKLEQYFDRINQVYVVLKVE
                     KVTHTSDATLHVNGGEIHASAEGQDMYAAIDGLIDKLARQLTKHKDKLKQH"
     gene            73952..74443
                     /gene="ptsN"
                     /locus_tag="IT892_000349"
     CDS             73952..74443
                     /gene="ptsN"
                     /locus_tag="IT892_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HAP3133599.1"
                     /translation="MTNNDTTLQLSSVLNRECTRSRVHCQSKKRALEIISELAAKQLS
                     LPPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDTLRAVGVFVQLETPIAFDAIDNQ
                     PVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAAQSDEELYQIITDTEGTP
                     DEA"
     gene            74489..75343
                     /gene="rapZ"
                     /locus_tag="IT892_000350"
     CDS             74489..75343
                     /gene="rapZ"
                     /locus_tag="IT892_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAP3133600.1"
                     /translation="MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTL
                     ADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRL
                     HPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
                     TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNF
                     IYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRH
                     RTLEKRKP"
     gene            75340..75612
                     /gene="npr"
                     /locus_tag="IT892_000351"
     CDS             75340..75612
                     /gene="npr"
                     /locus_tag="IT892_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS phosphocarrier protein NPr"
                     /protein_id="HAP3133601.1"
                     /translation="MTVKQTVEITNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEA
                     EANSVIALLMLDSAKGRQIEVEATGPQEEEALAAVIALFNSGFDED"
     gene            75826..76458
                     /gene="yrbL"
                     /locus_tag="IT892_000352"
     CDS             75826..76458
                     /gene="yrbL"
                     /locus_tag="IT892_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP regulatory network protein YrbL"
                     /protein_id="HAP3133602.1"
                     /translation="MIRLSEQSPLGTGRHRKCYAHPEDAQRCIKIVYHRGDGGDKEIR
                     RELKYYAHLGRRLKDWSGIPRYHGTVETDCGTGYVYDVIADFDGKPSITLTEFAEQCR
                     YEEDIAQLRQLLKQLKRYLQDNRIVTMSLKPQNILCHRISESEVIPVVCDNIGESTLI
                     PLATWSKWCCLRKQERLWKRFIAQPALAIALQKDLQPRESKTLALTSREA"
     gene            complement(76455..77183)
                     /gene="mtgA"
                     /locus_tag="IT892_000353"
     CDS             complement(76455..77183)
                     /gene="mtgA"
                     /locus_tag="IT892_000353"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HAP3133603.1"
                     /translation="MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAV
                     MVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEKA
                     LAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
                     YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRS
                     RQAWILRQMYQLGGEPFMQQHQLD"
     gene            complement(77180..77833)
                     /gene="elbB"
                     /locus_tag="IT892_000354"
     CDS             complement(77180..77833)
                     /gene="elbB"
                     /locus_tag="IT892_000354"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709007.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenoid biosynthesis glyoxalase ElbB"
                     /protein_id="HAP3133604.1"
                     /translation="MKKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQ
                     QVDVINHLTGEAMTETRNVLIEAARITRGEIRPLAQADAAELDALIVPGGFGAAKNLS
                     NFASLGSECTVDRELKALAQAMHQAGKPLGFMCIAPAMLPKIFDFPLRLTIGTDIDTA
                     EVLEEMGAEHVPCPVDDIVVDEDNKIVTTPAYMLAQNIAEAASGIDKLVSRVLVLAE"
     gene            complement(78063..80399)
                     /gene="arcB"
                     /locus_tag="IT892_000355"
     CDS             complement(78063..80399)
                     /gene="arcB"
                     /locus_tag="IT892_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobic respiration two-component sensor
                     histidine kinase ArcB"
                     /protein_id="HAP3133605.1"
                     /translation="MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTM
                     VLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDL
                     SLNVQLKDNIAQLNQEIAVREKAEAELQETFGQLKIEIKEREETQIQLEQQSSFLRSF
                     LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPADVYSPEAAAKVIETDEK
                     VFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDAL
                     ERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQEKYLKTIHVSAVTLGNI
                     FNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSALQAQQKGLRFNLEPTLPLPHQV
                     ITDGTRLRQILWNLISNAVKFTQQGQVTVRVRYDEGDMLHFEVEDSGIGIPQDELDKI
                     FAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVTSEQGKGSTFTLTIHAPSV
                     AEEVDDAFDEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFK
                     PGEYDLVLLDIQLPDMTGLDISRELTKRYPREDLPPLVALTANVLKDKQEYLNAGMDD
                     VLSKPLSVPALTAMIKKFWDTQDDEESTVTTEENSKSEALLDIPMLEQYLELVGPKLI
                     TDGLAVFEKMMPGYVSVLESNLTAQDKKGIVEEGHKIKGAAGSVGLRHLQQLGQQIQS
                     PDLPAWEDNVGEWIEEMKEEWRHDVEVLKAWVAKATKK"
     gene            complement(80495..81424)
                     /locus_tag="IT892_000356"
     CDS             complement(80495..81424)
                     /locus_tag="IT892_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312117.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAP3133606.1"
                     /translation="MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGG
                     CTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQ
                     QAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
                     HDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHI
                     VKGSIMAKAWEAGRLNGIELEDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWC
                     ENRWTGMVELDRYLNEHGVQGSALGRPWLPPTE"
     gene            82099..86559
                     /gene="gltB"
                     /locus_tag="IT892_000357"
     CDS             82099..86559
                     /gene="gltB"
                     /locus_tag="IT892_000357"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HAP3133607.1"
                     /translation="MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGA
                     ILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIV
                     EEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
                     RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPTDLPRFYLDLADLRLESAICLFHQRF
                     STNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLHDAAPFVNET
                     GSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWD
                     GPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVG
                     PGELMVIDTRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLSDEEVGSRELD
                     DDTLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQ
                     QFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLT
                     TMKEEHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLP
                     VPAPMAVGAIQTRLVDQSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETL
                     GRLIDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHDDV
                     VGLCFQGAVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPD
                     VVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFK
                     RFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGR
                     FGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHH
                     DIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGT
                     GASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAE
                     SFGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYFEFIARE
                     TRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHPGKALYCTEN
                     NPPFDNGLLNAQLLQQAKPFVDERQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLA
                     ADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSH
                     EASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCIL
                     GKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLSVDALAIHEEHLRGLITEHVQ
                     HTGSQRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ"
     gene            86572..87990
                     /locus_tag="IT892_000358"
     CDS             86572..87990
                     /locus_tag="IT892_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase"
                     /protein_id="HAP3133608.1"
                     /translation="MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQA
                     DRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDR
                     LCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLA
                     CADVLTRNGVKAVVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTE
                     VGRDVQLDDLLSDYDAVFLGVGTYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGE
                     TRDEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRRDEENMPGSRREVKN
                     AREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPA
                     DAVIMAFGFRPHNMEWLAKHSVELDSQGRIIAPEGSDNAFQTSNPKIFAGGDIVRGSD
                     LVVTAIAEGRKAADGIMNWLEV"
BASE COUNT        21535 a        23777 c        22038 g        20873 t
ORIGIN      
        1 tgagacttgc aattatagaa tctataccaa gagcaactct aacagatgaa ttagaaaatg
       61 aattaacaaa agaaatatat aaaagctcat cgaaaattaa caattacttg agcagaatta
      121 aattaccaga gatgaaagca ttctcattag aaaaaataga ttattacatc gatataatca
      181 ttaaagatta tgaaagcgtc aaagaaaatg cttatctaat cgttccaaaa attaattaca
      241 atacagattt aaacatagag gactctagct cagaggaatt ccttccagat aatacaatcg
      301 agaaagacga aaattctcca gacaattgct ttgaagtcgt aaaatataat acatatgaag
      361 cttataactc agagaagcaa tattatacca gagaggacta tacgtatgat tacgaccttt
      421 taaatgcaat atagacttaa taacttctta caaagtctat tattaatacc gtagatattc
      481 atcttaccct gtgcaccaaa agcaaaaact tatcgacgcg ggtttgaaac tgattgcaac
      541 cgcaaaaatg cctgatgcgc tacgcttatc aggcctacgc catctctgca atatattgaa
      601 tttgcgtgct tttgtaggca ggataaggcg ttcacgccgc atccggcatg aataaagcgc
      661 actcaacaat ctgaaacccg ccagtttacg ctgccgggtt ttcgttaaaa gaggtgaaac
      721 tgaccaataa gccgctttct tttgagtata gtgtcgtgga cagtcattca tctttctgcc
      781 cctccaaaag caaaaacccg ccgaagcggg tttttacgta aatcaggtga aactgaccga
      841 taagccgggt tctgtcgtgg acagtcattc atctaggcca gcaatcgctc actggctcaa
      901 gcagcctacc cgggttcagt acgggccgta ccttatgaac ccctatttgg ccttgctccg
      961 ggtggagttt accgtgccac ggactgttac cagccgcgcg gtgcgctctt accgcaccct
     1021 ttcaccctta cctgatcccg cttgcgcggg ccatcggcgg tttgctctct gttgcactgg
     1081 tcgtgggttt cccccccagg cgttacctgg caccctgccc tatggagccc ggactttcct
     1141 cccctccgcc cgtctccccc gaagaggacg acgacgaagc ggcgactgtc tggtcagctt
     1201 cggcgcgcag tatagagggt ttgcgcgccc ttgtcacccc gcgttgcgca ttccaatcgc
     1261 cagtgtcgcg gcgatattac gtgaagcacg gtaaatattg tcataagccc cgcggaatgc
     1321 ttcgtccaac gtaccaatac tggtcaatac gctgaagacc gcatcaatgc catgctgatg
     1381 tacaacgcca acatcattgg tcaggctacc cgcaatgcca atcaccggtt tattgtactt
     1441 tttcgccacg tttgcgacgc caatcggaac cttgccgtgt atactctggc tgtcaatacg
     1501 cccttcaccg gtgatcacta gcgtacaatc gtgaatatgt tcctccagat tcagcgccgt
     1561 agtgacgatt tcaataccac ttttcagttc cgcaccaaga aacgccatta gcgccgcgcc
     1621 cataccaccc gcagctcctg cgccggggac atctttcaca tcaacatgca gcgctttttt
     1681 aatgacatcg gcatagtgag agaggttatt gtccagctca acaatcatcg cttcactggc
     1741 tcccttttgt gggccaaaga tgcgcgatgc accgttatcg cccaccagcg gattggtgac
     1801 atcacaagcg acgcgaatga cgcaatcttt taagcgcgga tcgaggccgg aaatatcaat
     1861 atcattcaga gtattaagac taccgccgcc aaaaccaatt tcattgccgt tggcgtcgca
     1921 taatttcgcc cccagcgcct gtaccatgcc tgcaccgcca tcatttgtag cgctaccgcc
     1981 aatgccgata ataatgtttg tcgcgccgct ctccagcgcc tgcaggatta actcgcctgt
     2041 gccgcgtgaa gtggtcacga gtggatcgcg tttttccgca ggtaccagct ccagcccact
     2101 ggccgccgcc atttcaataa acgcggtttt gccatcgccg gagatccccc aactggcatt
     2161 caccttctcg cccagcggcc ctgtaaccca ggcgtgacgt tcggaaccct gggtggctgc
     2221 aatcatcgct tccaccgttc cttcgccacc gtcggcaacc ggaacagaaa cgtactgtgc
     2281 atcaggaaaa atttcccgaa atcctttttc tatcgcctgc gcaacctcgc tggcagataa
     2341 actttcttta taagagtctg gggcgattac gattttcata cctatgcctg ttaccacatg
     2401 acgccggagg gcgtttctct tattcggcct ggattccagg cccggattgc aatacgccat
     2461 ccgggcacga cgtcattaac gagtaacttc gactttcgcc agtttttcgt agtagcacgc
     2521 cagggcgcta tgatctgccg ttcctaaacc atctgctcgc actgcctgca tcatctccat
     2581 aaccgcagct gtgagcggca gttgcgcgcc gacgccgtgg gaagtatcca gcgcatttgc
     2641 cagatcctta atatgcagat caatacggaa gcccggcttg aagttgcggt ccatcaccat
     2701 cggcgctttg gcatccagca cggtactgcc cgccagtcca ccgcgaattg cctgatacac
     2761 caaatccggg ttaacgcccg ctttggttgc cagcgttaac gcttctgaca tcgcggcaat
     2821 attcagcgcc acaatgacct gatttgccag tttggtgacg ttacctgcac cgatttcccc
     2881 ggtatgcacc acggaacccg ccatcgcttt catcaaatca tagtatttgt cgaaaatagc
     2941 cttgtcgccg cccaccatca ctgacagcgt accgtcgata gctttcggtt caccgccgct
     3001 caccggagca tccagcatat caatgccttt cgctttcagc gcttcgctga tttcacggct
     3061 tgccagcggt gcgatagaac tcatatcgat caataccgta cctggcttcg cgccttcaat
     3121 aatgccattc tcacccagcg ccacctcttt cacatgaggg gagtttggta gcatggttat
     3181 gatgacgtcg cactgttcag cgatcgcttt agccgtagag gctgtttctg cacctgcagc
     3241 aatcacgtca gcaatagctt ctgggttacg gtcagcaacc accagcgagt aacctgcttt
     3301 cagaaggttt ttactcattg gtttacccat aatccccagg ccaaaaaaac caactttcat
     3361 agtcatatca atcatctctc ttgttgcggt ggtggttatt ttttaaaggt atcagccagt
     3421 ttctgagtgg cagagcggaa gacgccgaga tcgctgccga cagccacaaa cgtcgccccc
     3481 cattccagat aacgacgcgc atcggcttcg accggtgcga ggataccgct gggtttgccg
     3541 tgcgcactgg cacggttaaa aatatgctga attgcttttt gtacatccgg gtgcgaggca
     3601 ttgccgagat ggcctaatgc cgcagccaga tcgctggggc cgacgaagat accgtctacg
     3661 ccttcggtag cggcaatggc atcgacgtta tctacgccct gctgactttc tatctggacc
     3721 agaatggtga tgttcttgtt cgactgagcg aaataatccg ccacggtgcc aaacatattg
     3781 gcgcggtgag aaacggagac gccgcgaatg ccttccggtg ggtaacgggt tgatgccacc
     3841 gcctgctctg cttcctcttt tgtttctaca aaaggaatca ggaagttata gaaaccgata
     3901 tccagaagac gcttaataat taccggctcg ttggtcggca ctcgcactac tggcgcgctg
     3961 gcgctgcctt tcagggccat taactgcgga ataaacgtgg agatatcgtt tggcgcatgt
     4021 tcgccatcca gcaccagcca gtcaaaccca gccaaaccaa gaacttcagt gctaatcggg
     4081 ttagagagtg ctgaccagca accaatttgt acctgtttcg cagccagtgc ggctttgaat
     4141 ttattcggga aaacatcgtt attcatcgct tatacctttg cttatttctg caattccata
     4201 cgtttaatgt cgccaactac aaagaggtag cagaccatcg ccatcagcgc tgaacatccc
     4261 acgaaaacca gtgctgcatt gaaggagtgc agttcactta ccagatagcc aatcaccagt
     4321 ggagtgacaa tggaggcaac attgccaaag acgttaaaga cgccgccgca gaggccaaca
     4381 atctctttcg gcgcggtgtc agaaattacc ggccagccca gcgcaccaaa tcctttgcca
     4441 aagaaagcca gcgccatcag catgaccacc agcgtggtgt tgttggtgta gttacataag
     4501 atgatggtgg aagccagcaa cattcccagc acaatcggta gcttacgtgc cagggtcagg
     4561 gacaaaccgc gtttgatcag ataatccgag aagacacctc ccagcacgcc gcccgcaaag
     4621 ccacacagtg ccggaatcga ggcgaccaga cccactttca gaatcgacat gcctttttcc
     4681 tgcaccagat aaattgggaa ccaggtgagg aaaaaccagg tgatggtgtt gataaaatat
     4741 tgtccgaaaa atacgcccag catcatgcgg ttagagagca attgcttgat gtaatgcagt
     4801 ttgggaccgc ttgctgccgc actgcccggc tttttatggt ccatatcgac caccgcgcca
     4861 ttttctgaga taaacttcag ctcttccgca gacatacgtg ggtgatctgt cgggttatga
     4921 atcaacttga tccacagcgc cgtcagcaca aaaccaatta cccccataac ggtaaagacg
     4981 tgctcccagc cccaggcgaa agtcagccag ccaagcagcg gcgaaaagag cgccagcgag
     5041 aaatattgcg ccgagttaaa gatggcggag gcagtaccac gttctttcgt cgggaaccag
     5101 gcggcgacaa tacgggcgtt cgccgggaat gatggcgctt ccgagaaccc cagcataaag
     5161 cgcataaaga acatggagat ccctgcccag gccaacggga acatatcaac aaagccttgc
     5221 aggaaggtga acagcgacca gaaaaagagg ctgtaggtgt aaactttttt cgagccaaac
     5281 ttatcaagca accagccgcc ggggatttgc atcagcaggt aggcccagcc aaaagcggag
     5341 aagatgtaac ccatcgaaac cgcacttaac tgcaactctt ttgccacttc ggtaccagca
     5401 atagacagcg ttgcacgatc ggcgtagtta acggcggtaa caataaaaat aatcagtaat
     5461 attaaatagc gggtatgcac gcctttcttt tttacgtcaa cggtgtctag aatcatttta
     5521 tttacctcgg gtacttatgc tgatttttat tattatgggg aaggtgttat ttatgagttt
     5581 tatttatgcc gttacggcaa tgaactcggg aattagtata agcagcgcga gaataataat
     5641 cattgtgcaa atgctaattt aattaatact atttaaatat tattttgagc atatgcacat
     5701 aaggttgcgc gctaaagcac agatttgcgc tttaccttac cgtgcggcac tgcaatccct
     5761 gaaatgattg acattgatca catttctgcg tttaaactcc tgacattctt atttcaccca
     5821 atgaagtcat ttatttttaa atgagaccag gtcctcattt taataacccc tggctggaga
     5881 atattgcaca atggccaaca tcgaaatcag acaagaaacg ccaactgcgt tttatataaa
     5941 agttcacgac acagataatg tggcaattat tgttaatgat aatggcctga aagcaggaac
     6001 gcgttttccg gatgggctgg aattaattga acatattccc caggggcata aagtcgcatt
     6061 gctggacatt ccggctaatg gtgaaattat tcgttatggc gaagtgattg gttacgccgt
     6121 gcgcgcaatc ccacgcggaa gctggatcga cgaatcaatg gttgtactac cggaagcgcc
     6181 gccgttacac acgctgccac tggcaaccaa agtcccggcc cccttaccgc cactggaagg
     6241 atacaccttt gagggctatc gcaatgccga tggcagcgtg ggcaccaaaa acctgctcgg
     6301 catcaccacc agcgtccact gtgtggcagg cgtggtggac tatgtagtaa aaatcattga
     6361 acgcgatctg ctaccgaaat acccgaacgt cgatggcgtg gtggggctga atcatttgta
     6421 cggctgtggc gtggcgatta atgcaccggc ggcagtggtg cctattcgta ccatccacaa
     6481 tatttcgctg aaccctaact ttggcggcga agtaatggtg attggtctgg gttgtgaaaa
     6541 gttgcagcct gagcgcctgc tgactggaac ggatgatgtg caagctattc cagtagaaag
     6601 cgccagcatt gtcagtttgc aggatgaaaa gcatgtcggc tttcagtcca tggtcgagga
     6661 tattttgcag gtcgccgaac gccatttgca caaactgaat caacggcagc gagaaacctg
     6721 tccggcttca gaactggttg tcggcatgca gtgcggcggc agcgatgcgt tttctggcgt
     6781 aacggcaaac ccggcggttg ggtatgcgtc tgatctactg gtgcgctgcg gcgcaacggt
     6841 gatgttttca gaagtcacgg aagtgcgtga cgcgatccat ctgctgacac cacgcgcagt
     6901 gaacgaagag gtcggcaaac ggctgctgga ggagatggag tggtacgata actatctcaa
     6961 tatgggaaaa accgaccgca gcgccaaccc ttcgccgggc aacaagaaag gcggtctggc
     7021 aaacgtggtg gagaaagcgc tcggctccat tgctaaatcg ggtaaaagtg caattgttga
     7081 agtgctgtcg cccggtcaac gcccgactaa acgcggatta atttacgccg cgacgccagc
     7141 cagcgatttt gtctgtggca cgcaacaggt ggcttcaggg attaccgtgc aagtgtttac
     7201 gaccggtcgc ggtacgccgt acggcctgat ggcggtaccc gtcattaaaa tggcgacccg
     7261 caccgagctg gcgaaccgct ggtttgattt aatggatatt aatgcgggca ccatcgctac
     7321 cggcgaagaa actattgaag aggtgggctg gaagttgttc cactttattc tcgacgtcgc
     7381 cagcgggaag aagaaaacct tctcagatca atggggactg cataaccagc tggcggtgtt
     7441 taacccagca ccggtgacct gatttctttt ggaacgtccc tcgcaaaaca tggccttagt
     7501 gccatgtttt tattgtttaa agtccccacg tccattaata atgcatttgc attaccttag
     7561 ttcaagctta taatttgagc agaaaacagg ctgtaaaagg acagtgaatc atgcccgcta
     7621 atgctcgctc tcacgctgta ctgaccactg aatcaaaggt cacgatacgc ggacaaacaa
     7681 ctatccccgc gccagtgcgt gaggccttaa aactgaagcc aggccaggac agcattcatt
     7741 acgaaattct gcctggtggg caagtattta tgtgccgact gggagatgaa caggaggatc
     7801 atactatgaa tgcatttttg cgttttctgg atgcagatat ccagaacaac ccgcaaaaaa
     7861 ctcgtccatt caacattcaa caaggaaaga aacttgtcgc tggcatggac gtcaacattg
     7921 atgatgagat tggcgacgac gaataatgga ttttccacaa agggttaatg gttgggcgct
     7981 atatgctcat ccctgttttc aggaaaccta cgacgcttta gttgccgaag tcgagacatt
     8041 aaagggaaaa gatcctgaaa attatcagag aaaagccgcc acaaagttat tggcggtagt
     8101 ccataaagtg attgaggagc atatcacggt caatccatca tcaccggcat tccgtcatgg
     8161 caagtcgtta ggctctggga aaaataaaga ctggtcacgg gtaaaatttg gtgctggtcg
     8221 ttatcgtctc ttctttcgtt atagtgaaaa agagaaagtc atcattctgg gatggatgaa
     8281 cgatgaaaac actctgcgca cctacggtaa aaaaacagat gcctataccg tattcagcaa
     8341 aatgttaaaa agaggacatc ctcctgccga ctgggaaacc ctcacccgag agacagaaga
     8401 accccattga tggtgttcac aatgcccgcc gaacgcattc gtgttgacca gcgggcaccc
     8461 tttctcactc cccgaccaga atcacttcaa ccccagcctt tcgcagccct tccaggctat
     8521 ccgcaggaat gccttcatca acaatgatca tgtcgatacg ttgagtatca atgatcttat
     8581 gtaaactgga acgattgaat ttactggaat cggtgaccac gatgatccgt tccgcaactt
     8641 cgcacatccg gcggtttaaa cgggcttcat cttcattatg cgtactgacg ccgcgctcca
     8701 gatcgatcgc atctacgcca agaaacagca tatcgaagtg gtaattttgc agcgattgtt
     8761 cagcctgatc gccgtaaaaa gattgcgact gacggcgcaa atgcccgccg gtcatcagca
     8821 gctcaacgcc ttccgcttcc agcaacgcat tagccacgtt cataccgttg gtcatcgcaa
     8881 ttacgtcagt gtgcttgcgc atcagacgag caatctcaaa agtggtggtc ccggaatcga
     8941 ggatcacccg atgacctggc tgaatcaact caacggcagc tttcgcaacg ctgcgtttca
     9001 tcgcggtgtt cagcgcgctt ttatcttcca ctgatggctc gactgacggc gtggtgctat
     9061 cgcagatcaa cgcgccgcca taggcacgca cagcgatccc ctgcttttcc agaaacgcca
     9121 gatcgttgcg gatcgtcaca gtagatacgc catacaatgc cgacagatcg ttaacctgca
     9181 cactcccttg ctgtcgcaga cgctgaatga tctgttctcg tcgctcgctg gtgcctgtca
     9241 ttcgcttctc acctgaagcg tcggtattac tcatagtaag tcctttcgta aaactttcgt
     9301 ttcatttcgt tttgcctatt aacgcctttc tattaagcaa atgcaagccc accttaccca
     9361 ttggcgcaag ctactctcgt ttcagtggct ttcattatgt ttcttttgtg aatcagatca
     9421 gaaaactatt atctttcgtt ttatttttat ctcaccatgg cgcagtatca actgaaacaa
     9481 aacgaaagat taatatcgca gtaatctgaa ctggagagga aagtgaaaca tctgacagaa
     9541 atggtgagac agcacaaaga gggcaaaaca aatgggattt atgccgtttg ttccgcacat
     9601 ccgctggtgc tggaagctgc aatccgctac gccagtgcaa accaaacgcc gttactgatt
     9661 gaagcaacct ccaatcaggt agaccagttc ggcggttata ccggaatgac gcccgccgat
     9721 tttcgcggct ttgtttgtca gctcgccgac tcgttgaatt tcccacagga tgcgttgatt
     9781 ctgggtggcg accatctggg tccaaaccgc tggcaaagcc tgcctgccgc tcaggcaatg
     9841 gccaatgccg atgatttgat taaaagctac gtggcggcag gattcaaaaa aattcacctt
     9901 gattgcagca tgtcctgtca ggacgatcca attcccttaa ctgatgacat cgtggctgaa
     9961 cgcgccgcac gtctggcgaa agtggcggaa gaaacctgtc ttgaacactt tggcgaagcc
    10021 gatctggagt atgtcattgg taccgaagta ccggtacctg gcggcgcgca tgaaacctta
    10081 agcgagctgg cggtcaccac gccggatgcc gcccgcgcca cgctggaagc ccatcgtcac
    10141 gcctttgaaa agcaaggttt gaatgccatc tggtcacgca tcattgccct ggtggttcaa
    10201 cccggcgtcg aattcgatca caccaacgtt attgattatc agcccgccaa agcgagcgcc
    10261 ttaagccaga tggtcgaaaa ctacgaaacg ctgattttcg aagcgcactc taccgattat
    10321 caaacgccgc aatcgctgcg ccagctggtg attgaccact ttgccattct gaaagttggc
    10381 ccggcgctga ccttcgccct gcgtgaagct ctgttctctc tggcggcgat tgaagaagaa
    10441 ctggtaccag cgaaagcctg ttccggtctg cgtcaggtgc tggaaaacgt gatgctcgac
    10501 cgcccggaat actggcaaag ccactaccac ggtgacggca acgcacgtcg cctggcgcgt
    10561 ggttatagct actcggatcg cgtgcgctat tactggccgg acagccagat tgatgacgct
    10621 ttcgctcatc tggttcgtaa tctggcggat tcaccaattc cgctaccgct catcagccag
    10681 tatctgccgc tgcaatacgt gaaagttcgc tccggcaagc tgcaaccgac gccacgggaa
    10741 ctcattatca accatattca ggacatcctg gcgcagtacc acacagcctg tgaaggccaa
    10801 taagcaaaac aaagaggaac acgctatgcc aaatattgtt ttaagccgga ttgatgaacg
    10861 cttgattcac ggtcaggtcg gcgttcagtg ggtcggattt gcgggggcaa atctggtgct
    10921 ggtagccaac gatgaggttg ccgaagatcc ggtacaacaa aacctgatgg aaatggtact
    10981 ggcagaaggg atcgccgtac gtttctggac gctgcaaaaa gtcatcgaca acattcatcg
    11041 cgccgccgat cgacagaaaa tcctgctggt ttgtaaaaca cctgccgatt tcctgacgct
    11101 ggtgaaaggt ggcgttccgg tgaatcgcat taacgttggc aatatgcact acgccaatgg
    11161 caagcaacaa atcgccaaaa cggtttctgt ggatgcgggc gatatcgcag catttaacga
    11221 cctgaaagcc gctggggtgg aatgcttcgt tcagggcgtc ccgacagagc ctgctgtgga
    11281 cctctttaaa ttactttgag ggattcatca tggaaatcag tctgttgcag gcattcgcgt
    11341 tgggcattat cgcctttatc gctggcctgg atatgtttaa cggcttaacc catatgcacc
    11401 gcccggtggt cctcggccca ttggtcgggc tggtacttgg cgatctgcat accggtattt
    11461 taaccggcgg tacgctggaa ctggtgtgga tggggctggc cccgctggca ggcgcacaac
    11521 cgcctaacgt gattatcggt actatcgtcg gcacggcgtt tgccattact actggcgtga
    11581 aacccgatgt cgcggtcggt gtcgccgtac ctttcgctgt cgcagtacag atggggatta
    11641 ccttcctgtt ctcggtgatg tctggcgtga tgtcccgctg cgaccggatg gcggagaacg
    11701 ccgatacacg cggcattgaa cgcgtgaact atctggcatt gctggcactc ggcactttct
    11761 attttctctg cgctttcctg cctatctact tcggcgcaga acatgccaaa accatcattg
    11821 atgtcctgcc gcaacgatta atcgacggcc tcggcgtcgc gggcggcatc atgccagcaa
    11881 tcggttttgc cgtgctgctg aaaatcatga tgaaaaacgt ctacatcccc tacttcatcc
    11941 tgggctttgt tgccgcagcc tggctcaagt tacctgtgct ggctattgct gccgccgcgc
    12001 tggcgatggc gctgatcgac ctgctgcgta aatctcctga accgactcaa cctgcggcac
    12061 agaaagagga atttgaagat ggcatctaat caaaccaccc tgccgaacgt cagtgaaaac
    12121 gaagaaacac tgctgactgg cgtcaatgaa aacgtgtatg aagatcagag cattggcgcg
    12181 gagctgacga aaaaagatat caaccgcgtc gcctggcgtt ccatgctgtt acaagcgtct
    12241 tttaactacg aacgtatgca ggcttctggc tggttgtacg gtctgctgcc tgctctgaaa
    12301 aagatccaca ctaataaacg cgacctggcg cgcgccatga aagggcatat gggtttcttc
    12361 aatacccatc cgtttctggt gacgtttgtt atcggcatta tccttgcgat ggagcgttct
    12421 aagcaggacg ttaacagtat tcagagcacc aaaattgccg tcggtgcgcc gctcggcggg
    12481 attggcgatg cgatgttctg gctaacgcta ctgccgattt gtggcgggat aggcgcaagc
    12541 ctcgcgctac aaggctctat tcttggcgct gtcgtcttta ttgtgctgtt caacgtggtg
    12601 cacctggggc tgcgttttgg tctggcgcat tatgcttacc gcatgggcgt ggcggcgatt
    12661 ccactcatta aagcaaatac caaaaaagtc ggccatgcgg catctatcgt tgggatgacg
    12721 gtaatcggcg cgctggtggc aacctatgtt cgtttaagca ccacgctgga aatcaccgcg
    12781 ggcgacgcag tggttaagtt acaggctgat gttatcgaca aactgatgcc agccttctta
    12841 ccgctggtct acaccctgac catgttctgg ctggtacgcc gcggctggag tccgctgcgc
    12901 ctgattgcga ttaccgtggt tctcggcatc gtcggtaaat tctgccattt cctttaaata
    12961 caatgaggta ttagatgtta agtattattt tgacagggca tggcggattt gccagcggca
    13021 tggaaaaagc aatgaagcaa atcctcggcg agcaatcgca gtttattgcc atcgattttc
    13081 ccgaaacctc aagcaccgcg ctgcttacat cgcagcttga agaggccatc gcccaactcg
    13141 attgtgaaga cggcattgtt tttctgacgg atttgctggg cggcacgccg tttcgcgtag
    13201 cttcaacgct ggcgatgcaa aaaccgggct gtgaagtgat caccggcacc aatttgcaac
    13261 tgctactgga gatggtgctg gagcgcgaag ggttaagcgg tgaagagttc cgtgtgcagg
    13321 cgctggagtg tggacatcgt gggctgacca gtctggtgga cgagttaggc cgctgccatg
    13381 aagaatgtcc ggtcgaggaa ggaatatgac acacgttctg cgcgccagaa ggctgctgac
    13441 tgaagaggga tggctcgatg accatcagtt gcgtattgct gacggtgtaa tcgcagcaat
    13501 cgaaccgatt ccagtgggcg tgactgaacg cgatgcggaa ctgctctgcc ccgcttacat
    13561 cgacacccat gtacatggtg gtgcgggcgt tgatgtaatg gatgacgcgc cggatgtgct
    13621 cgacaagctg gcaatgcaca aagcacgcga aggtgtcggc agttggttac cgaccaccgt
    13681 aaccgcgccg cttaatacca ttcatgcggc gctgaaacgt attgctcaac gttgccaacg
    13741 cggcggacct ggtgcgcaag tgctggggag ttatctcgaa ggaccgtact tcacgccgca
    13801 gaataaaggc gcgcatccgc cggagctgtt tcgcgagctg gaaattgccg agctggatca
    13861 attgattgcc gtttctcagc acaccttgcg cgtggtagcg ctggcaccgg aaaaagaagg
    13921 ggcattgcag gccatccgcc atcttaaaca gcaaaacgta cgggtgatgc tggggcatag
    13981 cgcggcgacc tggcaacaaa cccgtgccgc gtttgacgct ggtgccgacg gcctggtgca
    14041 ttgctataac gggatgacag gtttacatca ccgcgaaccg ggaatggttg gcgcgggatt
    14101 aacggacaag cgcgcctggc tggaactgat agccgatggt catcatgtgc atccggcggc
    14161 gatgtcgctg tgttgttgct gtgcgaaaga gagaatcgtg ctgatcaccg acgcgatgca
    14221 ggcagccggg atgccggatg gtcgctatac gttatgtggc gaagaagtgc agatgcacgg
    14281 tggcgttgtc cgtaccgcgt ccggtggact ggcgggcagt acgctgtctg ttgatgcggc
    14341 agtgcgcaat atggtcgagt tgacggacgt aacgcctgcg gaagccatcc atatggcgtc
    14401 gctgcatccg gcgcgtatgc tgggtgttga tgatgttctg ggatcgctta aaccgggcaa
    14461 acgcgccagc gtcgttgcgc tggatagcgg gctgcatgtg caacaaatct ggattcaggg
    14521 tcaattagct tcgttttgat ggtttgctcc tttattgggc cttcacttcc cccgtaaggc
    14581 ctttcttttt ctttcttttt gatctgtgca gcggtgtcgg atgcgacgct gacgcgtctt
    14641 atgcgaccta cggtacgccg catccggcaa tcggtgcaca tagcaacgtc atcatgcaat
    14701 tctttaatct tcccttgtct tttctttcaa cgatcacaaa tttcgtttta tttctttttt
    14761 ctccattgaa ctttcagttt cttttctata gattttaatc aacgaaagac atcaccaaat
    14821 gaaatgaaac gaaaggtaag cgaaagcgac aacgcccgac gtcaagttca tcagactaag
    14881 gattgagtta tgccagaaaa ttacacccct gctgctgccg caaccggtac atggactgaa
    14941 gaagagatcc gccatcagcc tcgcgcatgg atccgttcac tcaccaacat cgacgcgcta
    15001 cgttccgcgc tcaataactt ccttgaaccg ttactgcgca aagagaatct gcgggtaatc
    15061 ctgaccggag ccggaacctc ggcatttatc ggtgacatca tcgcgccgtg gctcgccagc
    15121 cataccgata aaaacttcag cgccgtaccg accaccgatc tggtcaccaa tccgatggac
    15181 tacctgaatc cagctcatcc actgctgttg atctccttcg gtcgatccgg caacagcccg
    15241 gaaagcgtcg ccgccgtgga actggcaaat caatttgtac ccgagtgcta tcacctgccg
    15301 atcacctgca acgaagcggg cgctctttac caaaacgcga tcaacagcga caacgcgttt
    15361 gccctgctga tgcccgcaga aacgcacgat cgcggctttg cgatgaccag cagcattacc
    15421 accatgatgg ccagctgcct cgcggttttc gcacctgaga cgatcaacag ccagagcttc
    15481 cgcgacgtgg cggatcgttg ccaggcgatc ctgacctcac tgggcgattt cagcgaaggt
    15541 gtgtttggtt acgcaccgtg gaaacggatc gtttatctcg gcagcggtgg cttacagggc
    15601 gcagcacgcg agtcggcgct gaaagtactg gaactgacgg cgggtaaact ggcggccttt
    15661 tatgattccc cgaccggatt ccgtcatggc ccgaaatcgc tggtcgataa cgaaacgctg
    15721 gtggtggtat ttgtctccag ccacccttac acccgccagt atgatcttga tctgctggct
    15781 gaacttcgtc gtgacaacca ggcaatgcgc gtaatcgcta tcgccgcgga aagcaacgac
    15841 gttattaccg ccggtccaca tatcatcctg ccgccgtcac gtcactttat cgacgttgag
    15901 caggcatttt gcttcctgat gtacgcccag acgtttgcac tgatgcagtc gctgcacatg
    15961 ggcaatacgc cggatacccc atcagccagt ggcaccgtta accgcgtggt gcaaggcgta
    16021 atcattcatc cgtggcaggc ataagaggat cgcattatga gcattatctc caccaaatat
    16081 ctgttacagg acgcccaggc caatggctac gcggtgcctg cctttaacat tcataacgcc
    16141 gagacgatcc aggcgatcct cgaagtgtgc agtgaaatgc gatcgccggt gatcctcgcc
    16201 ggaacgccgg ggacctttaa acatatcgcg ctggaagaga tctacgccct gtgtagcgcc
    16261 tattccacaa cctacaacat gccactggcg ctgcatctcg accaccacga atcgctggat
    16321 gatattcgcc gtaaagtcca cgcaggcgtg cgcagtgcga tgatcgacgg cagccacttc
    16381 ccgtttgccg agaacgtaaa gctggtgaaa tcggttgtcg acttctgcca ctcacaggat
    16441 tgcagcgtgg aagcagaact gggccgcctg ggcggtgttg aagatgacat gagcgttgac
    16501 gccgaaagtg cattcctgac cgatccacaa gaagctaaac gctttgtcga actgactggc
    16561 gtcgacagcc tggcggtagc gattggtacg gcgcacggct tatacagcaa aacgccgaag
    16621 attgatttcc agcggctggc ggaaattcgt gaagtggtgg atgttcctct ggtgctgcat
    16681 ggtgccagcg atgtcccgga tgaatttgtc cgtcgcacta ttgaacttgg cgtcacaaaa
    16741 gtgaacgttg ccacagaatt aaaaatagcc ttcgctggcg cggttaaagc ctggtttgcg
    16801 gaaaatccgc agggtaatga tcctcgttat tatatgcgcg tcggtatgga tgcgatgaaa
    16861 gaagttgtca gaaataaaat taatgtctgt ggttcagcga atcgaatttc agcataatca
    16921 ttagtttttt atgatttatc ccaatgtact tcccgattaa tatcggggag tgccttaatg
    16981 gtaaaggaga taactaaacc ttaataaata catcagtaca ataccgcaac aataatatat
    17041 ttaaaaagat tatattattc aactttatgg tgaggattac acaatgagca gtccaaatat
    17101 tctcttaacc cgtattgata accgtctggt tcacggtcag gttggcgtga cctggacatc
    17161 caccatcggt gcgaatctgc tggtagtcgt ggatgatgtt gtcgctaacg atgatattca
    17221 acagaaatta atgggtatta ccgcagaaac ctacggcttt ggcattcgtt tctttactat
    17281 cgaaaaaacc attaacgtca tcggcaaagc tgcaccgcat cagaagatct tcctgatttg
    17341 ccgcacgcca caaacggtac gtaaattggt agaaggtggc attgacctga aagatgtcaa
    17401 cgtcggcaat atgcatttct cggaagggaa aaagcaaatc agcagtaaag tttatgtcga
    17461 tgaccaggat ctcacggact tacgttttat taaacaacgt ggcgtgaatg ttttcattca
    17521 ggacgtccct ggcgatcaaa aagaacaaat ccctgactaa atctaaaatc gccttaatat
    17581 tggtttgagg taataaaaat gcatgaaata accctacttc agggattatc cctggcggcg
    17641 ttagttttcg ttctggggat tgatttttgg ctggaagcct tatttttatt ccgcccgata
    17701 atcgtttgta ccctaactgg cgctattctc ggtgatattc agactggctt aattaccggt
    17761 ggtctgacag agttggcttt cgccggatta acccctgcag gtggtgttca gccgcccaac
    17821 ccgattatgg cgggtctgat gaccactgtc attgcatggt ctacgggcgt tgatgccaaa
    17881 acggcaattg gtcttggcct gccgtttagt ttgttaatgc agtacgtcat tctgttcttc
    17941 tattccgctt tctcattatt tatgaccaaa gccgataaat gcgcaaaaga ggcggatacg
    18001 gcagcgtttt cccgacttaa ctggacaacg atgctcatcg tcgcttcagc gtatgcggtg
    18061 attgctttcc tctgtactta cctggcacag ggggcgatgc aggcgctggt gaaagcgatg
    18121 cccgcctggc tgacccacgg ctttgaagtg gctggcggta ttctgcctgc cgttggtttt
    18181 ggcttgctgc tgcgcgtgat gttcaaagcg caatatatcc cttacctgat cgccggtttc
    18241 ctgtttgttt gctacatcca ggtcagcaac ctgttgccgg ttgccgtact gggcgcaggc
    18301 tttgcggtgt atgagttttt caatgcgaaa tcccggcagc aagcgcaacc gcagcccgtt
    18361 gccagtaaaa atgaagaaga ggactacagc aatgggatct gaaatcagta aaaaagatat
    18421 cacccgtctg ggctttcgtt cgtcactgct gcaagcgagc tttaattacg aaaggatgca
    18481 ggcgggcggt tttacctggg cgatgttgcc gatcctgaaa aagatttata aggacgacaa
    18541 accgggccta agcgcggcga tgaaagataa cctcgaattt attaataccc acccgaatct
    18601 ggtcggattc ctgatggggt tattaatttc gatggaagaa aaaggagaaa accgcgacac
    18661 cattaaaggc ctcaaagtag cactgtttgg cccaatcgcc gggattggcg atgcgatttt
    18721 ctggtttacc ttattgccga ttatggcggg aatttgctca tcatttgcca gccagggaaa
    18781 cttgctgggg ccgattctat ttttcgccgt ttacctgctt atctttttcc tgcgcgtcgg
    18841 ctggacccac gtcggttatt cagtcggcgt gaaggcgatc gataaagtgc gagagaactc
    18901 gcagatgatt gctcgctcgg caaccatcct cgggatcacg gtaatcggcg ggctgatcgc
    18961 ttcgtatgtg catattaacg tggtgacatc gtttgccatc gacagtaccc acagcgtcgc
    19021 gctgcaacag gatttcttcg ataaagtctt cccgaacatt ttaccgatgg cctacaccct
    19081 gctgatgtat tactttctgc gggtgaaaaa agcgcatccg gtgctgttaa tcggcgtgac
    19141 ttttgtgctc tctattgttt gttccgcatt cggcattttg taaatggaac gaggcactgc
    19201 gtctggtggt gcctctttac ttaaggaatt tcatcctgtg caaacccttc agcaagttga
    19261 aaactatatg gcgttaagtg aacgtgccag cgaatattta ttggccgtga tccgtagcaa
    19321 accggatgcc gtgatttgcc tggcgaccgg agccacgcca ttactgacgt atcattatct
    19381 ggtagaaaaa atccaccagc agcaggttga tgtcagccag ctcaccttcg tgaagctcga
    19441 cgaatgggtg gatctgccat taactatgcc tggtacctgc gaaactttcc tgcaacagca
    19501 tatcgtgcag ccgctggggc tgcgtgaaga ccagctcatc agctttcgct ccgaagagat
    19561 aaatgagaca gagtgcgaac gggtaacgca cctgattgcg cgcaaaggcg gtctggattt
    19621 atgcgttctc gggttgggga aaaacggtca tcttgggctg aacgaaccgg gagaaagcct
    19681 gcaaccggcc tgccatatca gtcaacttga tgccagaaca cagcaacatg agatgttaaa
    19741 aaccgcgggc cgtcccgtga ctcgtgggat caccttaggc ctgaaggata ttctcaatgc
    19801 ccgcgaagtt ttgttactgg tgactggcga aggaaagcag gatgcgacag aacgttttct
    19861 cacggctaaa gtctctaccg ctatcccggc ttcattttta tggctgcata actatttcac
    19921 atgcatgatt gatgagatgt gtcgtcgtta actcgcctgc tacaggcgtt gcaacgctat
    19981 tcctgctgcg acgcctgtaa tcactctccc tgctgctcca gtgcatactt atacagcgca
    20041 tttttcttca cgccgtgaat ttctgctgcc agcgccgccg cttttttcag cggcagttct
    20101 gcctgtagca gcgccagcgt gcgcagggca tcagcaggca ggtcatcttc ctgcgcttta
    20161 tggccttcga caatcagcac catttcgcct ttgcgacggt tttcatcttc tttgacccac
    20221 gccagcagct cgccaacggg cgcgccgtga atggtttccc aggttttggt cagctcacgc
    20281 gccagaacga cgtagcggga ttcgcctaat accgcaacga tatcttccag gctatctaac
    20341 agacggtggg tagattcata aaaaatcagc gtgcgcggct ccgcttcaat ggcttttagc
    20401 gcatcacggc ggccttttga tttggcaggt aaaaagcctt cataacaaaa acgatcggat
    20461 ggtaaacccg cggcgcttaa cgcagtgata gcagcacacg gcccgggtag cggcaccacg
    20521 cgaatccccg cttcacggca ggtacgcacc agatggtagc caggatcgtt aattagcggc
    20581 gttccggcat cggaaaccag cgcaatgttt tgcccctctt gcagcttcgc cagcagcgtt
    20641 tcggcttttt gttgttcgtt atggtcgtgc agcgcaaaca accgagcatt aatcccaaaa
    20701 tgttgcagca ataaaccggt gtgacgcgta tcctcggcgg caatcagatc aacggcctgt
    20761 aatacctcca acgcacgctg ggtgatatcc gccagattgc cgattggcgt cggtacaatg
    20821 taaagctggc cctgagaatt atccgccgat tggtgttgtt tcattgtgtc gtccgtattg
    20881 ccgatttaat attgagcatt gcgtaaaaaa aatatcactg gatacattat ggtaccctca
    20941 acattttctc gtttgaaagc cgcgcgttgt ctgcctgttg ttctggcagc cctgattttc
    21001 gccggttgtg gcacccatac tcccgatcag tccactgctt atatgcaggg cacggcgcag
    21061 gctgattctg ccttttacct gcaacagatg cagcaaagtt ctgatgatac caggatcaac
    21121 tggcaattac tcgccattcg tgcactggtg aaagaagaca aaaccgggca ggcggttgag
    21181 ttgtttaacc aactaccgca agaactgaac gattctcagc gtcgcgagaa aacactgctg
    21241 gcggcagaga ttaaactggc gcagaaagat tttgctggcg cgcaaaactt gctggcgaaa
    21301 atcacacctg cagatttaga acaaaaccag caagcgcgtt actggcaggc aaaaatcgat
    21361 gccagccagg ggcgtccttc cattgattta ctgcgcgcgt taattgctca ggaaccgctg
    21421 ctcggcgcga aagaaaaaca gcagaatatt gacgccacct ggcagacgct ctcctccatg
    21481 actcaggaac aggcgaatac gctggtgatc aacgccgacg aaaatattct gcaaggctgg
    21541 ctggatctgc agcgcgtctg gtttgataac cgtaacgatc ccgacatgat gaaagccggg
    21601 atcgccgact ggcagaaacg ttatccgaac aacccgggcg cgaaaattct gccaacgcag
    21661 ttggttaacg taaaagcgtt taaaccagcc tcgaccaaca aaatcgccct gctgttgccg
    21721 ctgaatggcc aggcagcggt atttggtcgc actattcagc aaggctttga agcggcgaaa
    21781 aatatcggca ctcagccagt ggcggctcag gtagctgccg cacctgccgc agacgtagca
    21841 gaacaacctc agccgcaaac cgtggatggc gttgccagcc cggcacaagc ctcggttagc
    21901 gatctgaccg gtgaacaacc tgcggcccag ccggtgcctg taagcgcccc ggcggcaacc
    21961 accgcagcgg taagcgcacc cgcgaatcca tccgcagagc tgaaaatcta cgatacatca
    22021 tcacaaccac ttagccagat cttaagccag gttcaacagg atggcgcgag tattgtggtc
    22081 ggtccgttgc tgaaaaataa cgttgaagag ttgctgaaga gcaacacccc gctgaacgtg
    22141 ctggcactga accagccgga gaacatcgaa aaccgcgtca atatttgtta cttcgcgctt
    22201 tcaccggaag acgaagcgcg cgatgcagcg cgtcatattc gtgaccaggg taaacaagcg
    22261 ccgctggtgc tgatcccacg cagttcattg ggcgatcgcg tagccaatgc gtttgcgcaa
    22321 gagtggcaga aactgggtgg cggcaccgtt ctgcaacaaa aatttggttc caccagcgaa
    22381 ttacgcgcgg gtgttaacgg cggttctggt attgctttaa cgggtagccc gattactccc
    22441 agagcgacaa ccgactccgg catgacgacc aacaatccaa cgctgcaaac cacgccaacc
    22501 gatgaccagt tcaccaataa tggcggtcgt gtcgatgcgg tgtacattgt ggcaacgccg
    22561 ggtgaaatcg cttttatcaa accgatgatc gccatgcgta acggtagcca gagcggtgca
    22621 acgctgtacg ccagttcccg cagcgcacaa ggcaccgcag gcccggattt ccgtctggag
    22681 atggaaggct tgcagtacag cgaaatcccg atgctggcag gcggtaatct gccgttaatg
    22741 cagcaggcgc tcagcgcggt gaacaacgat tattcgctgg ctcgcatgta tgcgatgggc
    22801 gtcgatgcct ggtcgttggc aaatcatttc tcacaaatgc gccaggttca gggttttgaa
    22861 atcaacggta ataccggaag tctgacggct aacccggatt gcgtgattaa caggaagtta
    22921 tcatggctac agtaccaaca aggtcaagta gtccccgcca gttaaccacc aaacagaccg
    22981 gcgatgcgtg ggaagcacaa gcgcgtcgct ggctggaagg caaaggactg cggtttatcg
    23041 ccgctaacgt gaacgagcgt ggcggcgaga tcgatctgat aatgcgtgaa ggccggacca
    23101 ccgtttttgt cgaggtgcgt taccgccgct ctgcgcttta tggcggcgcg gcagccagtg
    23161 tgacccgcag caaacaacac aaattattac agactgcccg cttgtggctc gcgcgtcata
    23221 atgggagttt tgatactgtg gattgccggt tcgatgtggt agccttcacc gggaatgagg
    23281 ttgagtggat taaggatgcc tttaatgacc actcataatt aaggtttaag gattagcgtg
    23341 caagaaagaa ttaaagcttg cttcactgaa agcattcaaa ctcaaattgc ggcggcagag
    23401 gcgcttccgg atgccatctc gcgtgcagcc atgacgctgg ttcagtctct gctcaatggc
    23461 aacaaaatcc tctgttgtgg taatggaact tccgctgcca atgcacagca ttttgctgcc
    23521 agcatgatca accgtttcga aacggagcgg cccagcttac ctgccattgc actaaatact
    23581 gataatgttg tcttaacggc gattgccaac gatcgcttac atgatgaagt gtatgcaaaa
    23641 caggtgcggg cgctgggtca tgcgggagat gtattgttag ccatttccac ccgtggcaac
    23701 agccgcgata ttgtaaaagc ggtagaagct gccgttacgc gtgatatgac cattgtggca
    23761 ttaaccggct atgacggcgg tgaacttgca ggtttgttag ggccacagga tgtggagatc
    23821 cgcattcctt cgcatcgtag tgctcgcatt caggaaatgc atatgctgac ggtaaattgc
    23881 ctgtgcgatc tgatcgataa cacgcttttc cctcaccagg atgtttaagg agaatacatg
    23941 aaggcattat cgccaatcgc agtccttctt tccgcgctgc tgttgcaagg ttgtgttgcc
    24001 gctgccgtag tgggtaccgc tgctgtaggt accaaagccg caactgaccc acgcagtgtc
    24061 ggcacccagg tggacgatgg taccctggaa gtgcgcgtaa acagcgcatt gtcgaaagac
    24121 gaacagatta agaaagaagc gcgcattaat gtaacggcct atcagggcaa agtgctgctg
    24181 gttgggcagt caccaaacgc tgaactttcg gctcgcgcca aacagattgc tatgggcgta
    24241 gacggtgcca acgaagtgta taacgagatt cgtcagggcc agccgattgg tctgggcgaa
    24301 gcgtctaacg atacgtggat caccaccaaa gtgcgttcgc agctcttaac cagcgacctg
    24361 gtgaaatcgt ccaacgtgaa agtgaccacc gaaaacggtg aagtgttcct gatggggctg
    24421 gtgactgaac gtgaagcgaa agcggcggca gatattgcca gccgggtaag cggcgtgaag
    24481 cgggtaacca cagcgtttac gtttattaaa tagcagccct tgtaatgcct gatgcgacgc
    24541 ttgccgcgtc ttatcaggcc tacaacgatg caaactgtag gtcgaataac gcgtttacgc
    24601 cgcatccgac atgttttccc tcaaatcaaa ccaacagcgc cagcccgccg acaatcacac
    24661 ctgacactgc caccatcgcc cccgtcagcc ataaggcttt cgccgggaac gctttacgca
    24721 acataatcag tgacggcaaa ctcaccgccg ggagcgtcat caacaatgcc agcgccggag
    24781 cgattcccat gcctgccagc atcatcgttt gtacaattgg aatttctgct gccgtgggaa
    24841 tgacaaacaa gcatcccgct accgccatcg caatcaccca catcaggctg ttatcgacag
    24901 caccatcagc atgggggaat aaccagacgc gagcggcacc caacaccagt actgcaagga
    24961 tgtaaaccgg gatcgtactc cagaaaagcg tccatagcgc cctgccccag cggctaaaaa
    25021 atccgccctg cgcttccggt atgtcaattt cgaccggtgc ctgcgtttgc ggtgtttcac
    25081 gcacccattt ttgcaccagc gtcgcaatca gcaacaccat caccagcccc gccaccagac
    25141 gaatcgccgc aaacccccag ccgaggacaa accccataaa caccagcgtc gccgggttta
    25201 acaacggatt ccccatccag aatgccagcg caccgcccat cgatacctgt tggcgacgca
    25261 ttcccgccgc gaccggagcc gcacagcagg tacacatcat acccggcagc gaaaacagcg
    25321 ttcccagcag cgtgccgcga aagcgcgatt gcccaagcgt acgcagcaac cagtcacgcg
    25381 ggatcagcac ctgaatcaac gaaccgagga tcacccccag caccgccgct ttccataccg
    25441 cgaggaaata gatcatcgcg taatccaacg ccgcctgcca cggattagca tccgcctgcg
    25501 caaggataga tttaccgata ctgtgggttt cggcagcagt aaacgctttg ccgtagtaag
    25561 gttgccattt cacataccag agaccagcaa tgacaacgag aaagaaaagc gcgggtttcc
    25621 accactgaat gggcgttgcc gcctgagatg aagactgacc agtcatagca ttccccagga
    25681 ataagatatg ataattgagc gcgtgaatat tacgctcgct atcaattctt gggaataatt
    25741 attcagctct tttgcgtaat tctgaagagc ttaaaatcgt cacaccttca tgctcaggcc
    25801 gcatcgcctc tgccagcatg acccgcgcca cgtctctcgc atcaatggat ttccagttac
    25861 cgggtaacaa acggaataga ggcgcaaaaa gcgtttcgtt catccgctgt ttgctacgat
    25921 cgcccagtaa catcgacggg cgagcaatgg tcaatttcgg ccagttctgg gcgattaatg
    25981 cttcttccat ctcccctttg acgcggttat agaaaaacgg cgagtgggca ttagcaccca
    26041 tagcactgac caccagcata tgctgcgcac cgagccgccg cccggttaat gcggtatcca
    26101 ccaccagcgt gtaatcggca tgaataaacg cctctttact ccccgcttct cgccgcgtgg
    26161 tgccgagaca acaaaacaca atgtcgatgg gatcggtgac ctgcgccagc gcgtcagtca
    26221 gttgcggatc atggggatta aacaccccgg gcatatcgcc caacggacgt cgcgtcggcg
    26281 cggctatggc gttaactttc ggttcgttaa tcaacatccg cagcaggtga ccgcccacca
    26341 gccccgttgc gcctgtaatc agtacctgac tcatcttcgc tcctttacag aattgtctgc
    26401 cttgcgctcc acggctcatg caccaggctt aatagaccat gaggtaatta tccccgattg
    26461 tgggaaattc gcctcatcca atgcaacatc gcggaggaag catgagtaag aaaattgccg
    26521 ttttaatcac tgatgaattt gaggattcag aatttacttc acccgcagac gagttccgta
    26581 aagccggaca cgaagtgatt accattgaaa aacaagcggg taaaacggtg aaaggcaaaa
    26641 aaggagaagc cagcgtggcc atcgataaat ccatcgatga agtgacgccc gcagagttcg
    26701 atgccctgct gctaccgggc ggtcattcac cagattatct gcgtggcgac aaccgttttg
    26761 tcaccttcac ccgcgatttt gtgaacagtg gcaaacctgt tttcgccatc tgtcacggtc
    26821 cccagttgct gatcagcgcc gatgtgatcc gtggtcgtaa gctgaccgcc gttaaaccaa
    26881 tcattattga tgttaaaaac gcgggcgcgg aattttacga tcaggaagtg gtggtcgata
    26941 aagatcagct ggttaccagc cgcacaccgg acgatctgcc agcgtttaac cgcgaggcat
    27001 tacgcctgct cggttcctga gttacgtagc cagatcattt ttttaccaaa gcccagcgtg
    27061 ttgtcggtga atttgatttc atcaagccgg atttcccaca ccggggccga cagcattctg
    27121 gcaaccggaa agcgacgatt gtacgcctgg cgtgcgaggt cgctttcctc accttcaagc
    27181 ctgcggatct cgcctttaaa ttgcatgccg cgaattaacg ctaccgtttt cggctgaccg
    27241 tttaccgttc cggcaactgc cgcctgcggc ccactcatct gcgcgtggcg cgttttttct
    27301 tccgtcaaaa tgtagaaggc gactttctgc gcatcaaaaa gataaaaggc attagcgcac
    27361 cagagttccc cttcctgctg cacacaccag gtgacaacat gttgttttgc cagccaacgg
    27421 ctgatggcgg tgagtgtttc catagctgtt ctcttttata ctgtggcctg accttaacat
    27481 gcgacgcaga cgatgacacc ctggtttctt tacttgatcc gtaccgccga caataagctt
    27541 tataccggga tcaccacaga tgtcgaacgc cgctatcagc agcaccaaag cggcaaaggg
    27601 gcgaaagcac tgcgcgggaa aggagaacta acgctggcgt tttccgcgcc agtgggcgat
    27661 cgttcactgg cactacgggc ggaatatcgc gttaagaaac tgaccaaacg gcaaaaagag
    27721 cgtctggtag cggaaggcgc agggtttgca gagctgttga gcagcctgca aaccccggag
    27781 attaaaagcg attgaagtgc tcgtgatact caaccagacc ggttacgccg ttcagcgcgt
    27841 catccgctaa acgatgtacc tggaaggcgc tttcagtgcc cggccagcag caacgcagat
    27901 cgtgatgcgc cgccagctca aagccgaaac gactgtacag cgccggatcg cccagcgtca
    27961 ccactgcggc atagccgaac tcattaagcg aatcgagtcc ttcatagacc agttggcgtg
    28021 ccagcccctg tccacggtat ttttcatcaa ccgccaacgg tgccatgccg acccattgca
    28081 ggtcttcgcc ctgcacatca accggactaa atgccacata gccaatgacc tgaccttcgt
    28141 catctgtcgc caccagcccc agcgtcagaa agccatcttc acgcagatcg tgaaccagct
    28201 tcgcttccgc atcactttcg aatgaacgac gcagcagggc atcaataccc ggcgcatcaa
    28261 tgggaatttc tactcgaatt agcatggttc acctaccgat gtctgtttgg tttcaggcgc
    28321 ggttttcatt cccgcctcaa caaaatccgc cagttgcagc agcatcatgc gtaaggcttt
    28381 cggcatttgc tccagttcaa tggcgtccat caggtttttc acatacagcc ccagctccgt
    28441 atcgccttca atcgccagcc gacgctggaa gaagagcgta tccggatctt gtttacgcgc
    28501 cgcaatcatc agcagatcgc tggcgtcggc actaaaactc acatcagctt gcgcgttctg
    28561 gctaacgacc agtttgccat tcaccaccga ggtaaaccat tgcaggtcaa tatcacgcac
    28621 atgaatactt aaccagcggc cttcaagaaa ctccagctcg ccatcatcca gcgcctgacg
    28681 gaattgccag cttaagacct gctcaagaac ctggcgtttt agcgcaaatg gcgtcagttt
    28741 taccggtaca ctcaacagag atggccccaa atgcacaata cgggaacgca gtttatccaa
    28801 cacgagtttt actccctgtt tcaacaatca tcctattttg ccatatcaga aaaataacat
    28861 agcggtataa atcaacaatt ccatatgaaa ttgctgctac caccaataca actttaactg
    28921 ccttaaatca aaaattgtcg cagcaaggtt aactaaaatc ccagttcgtt aacatttttg
    28981 cgctttgata gcgcaacctt caggaaaaat tatggagctg ctctgccctg ccggaaatct
    29041 cccggcgctt aaggcggcca tcgaaaacgg cgcagatgct gtttatatcg ggctaaaaga
    29101 tgatactaat gcccgtcact tcgccggcct taactttacc gagaaaaaat tgcaggaagc
    29161 ggtgagtttt gtccatcaac atcgccgcaa acttcacatc gcgattaaca cttttgcgca
    29221 tccggacggt tacgcccgct ggcagcgcgc cgtggatatg gcggcgcagc tgggtgccga
    29281 cgcgctgatc ctcgccgacc tcgccatgct ggagtacgcc gccgagcgtt acccgcatat
    29341 tgaacgtcac gtatcggtgc aggcttcggc gaccaatgaa gaggcgatta acttttatca
    29401 tcgccatttt gacgttgcac gcgtggtgct gccgcgcgtg ttgtcgattc atcaggtgaa
    29461 acaactggcg cgggtcacgc ctgtaccact ggaagtattc gctttcggca gcctgtgcat
    29521 tatgtcggaa ggccgttgct atctgtcgtc gtatctgacg ggtgagtcgc ccaacactgt
    29581 gggtgcgtgt tctccggccc gtttcgtgcg ctggcagcaa acgccgcagg ggctggaatc
    29641 ccgcctgaac gaagtgctga tcgaccgtta tcaggacggc gaaaacgcag gttatccgac
    29701 gctgtgtaaa gggcgttatc tggtggacgg cgagcgctat cacgcgctgg aagaacccac
    29761 cagtctcaat accctggaac tgctgccgga gttaatggcg gcgaatatcg cttcggtgaa
    29821 aattgaaggc cgccagcgta gcccggcgta tgtcagccag gtggcaaaag tctggcgtca
    29881 ggctatcgac cgttgtaagg ccgatccgca aaacttcata ccgcaaagcg cgtggatgga
    29941 gacgctcggg tcgatgtccg aaggcacgca gaccaccctt ggcgcgtatc accgtaaatg
    30001 gcagtgagaa gagcaatgaa atattcctta gggccagtgc tgtggtactg gccaaaagag
    30061 acgctggaag aattttatca gcaggccgcc accagcagcg ccgacgtgat ttatcttggt
    30121 gaagcggtct gtagcaagcg ccgggcaacc aaagttggcg actggctgga gatggcaaaa
    30181 tcgctcgccg gaagtggtaa gcagattgtg ctctccacgc tggcgctggt gcaggcatcc
    30241 tccgaactgg gcgaactgaa acgctatgtt gagaacggtg agtttctgat tgaagccagc
    30301 gatctcggcg tggtgaatat gtgcgctgaa cgcaaactgc cgttcgtcgc cgggcacgcg
    30361 ctgaactgct acaacgcggt gacactgaaa atattgctca aacagggcat gatgcgctgg
    30421 tgtatgccgg tggagctatc ccgcgactgg ctggtgaatc tgcttaatca gtgcgatgag
    30481 ctgggcattc gcaaccagtt tgaagtggaa gtcctgagct acggtcatct gccgctggcc
    30541 tactccgccc gctgctttac cgcgcgttcg gaagaccgcc cgaaagatga gtgtgaaacc
    30601 tgctgcatta agtatccgaa cgggcgcaac gtgctatcgc aggaaaacca acaagtgttt
    30661 gtactcaatg gcattcagac catgagcggc tacgtttaca acctcggtaa cgagctgaca
    30721 tccatgcagg ggctggtcga tgtggtccgc ctgtcaccgc agggtactga cactttcgcg
    30781 atgctcgacg ccttccgcgc taatgaaaat ggcgcggcac cactgccgtt gacggcaaac
    30841 agcgattgta acggctactg gcggcggctg gccgggctgg agctgcaagc gtaagtatat
    30901 agctcacttt gttaacaact ttaactactc tttaatgcag tattaaagat taatcggtaa
    30961 caaagtgagc tgttatgact gataaaacca ttccgttttc gctactcgat ctggccccta
    31021 ttcccgaagg ttcttcagcg cgagaagcgt tctcccactc tctcgacctc gcccgtctgg
    31081 ctgaaaagcg cggctatcat cgctactggc tggctgaaca ccacaatatg accggtattg
    31141 ccagtgctgc aacatcagta ttgattggct atctggcggc gaataccact acgctgcatc
    31201 tggggtctgg cggcgtgatg ttgcctaatc actcaccatt ggtgatcgcc gaacagttcg
    31261 gcacgcttaa tacgctctat ccggggcgaa tcgatttggg gctgggtcgt gctccgggta
    31321 gtgaccagcg aaccatgatg gctctacgtc gtcatatgag cggcgatatt gataatttcc
    31381 cccgcgatgt cgcggagctg gtggactggt ttgacgcccg cgatcccaat ccgcatgtgc
    31441 gcccggtacc gggctatggc gagaaaatcc ccgtgtggtt gttaggctcc agcctttaca
    31501 gcgcgcaact ggcggcgcag cttggtctgc cgtttgcgtt tgcctcacac ttcgcgccgg
    31561 atatgttgtt ccaggcgctg catctttatc gcagcaactt caaaccgtcg gcacggctgg
    31621 aaaaaccgta tgcgatggtg tgcatcaata ttatcgccgc cgacagcaac cgcgacgctg
    31681 aatttctctt tacctcaatg cagcaagcct ttgtgaagct gcgccgtggc gaaaccgggc
    31741 aactaccgcc gccgattcaa aatatggatc agttctggtc accgtccgag cagtatggcg
    31801 tgcagcaggc gctgagtatg tcgctggtgg gtgataaagc gaaagtgcgt catggcttgc
    31861 agtcgatcct gcgcgaaacc gacgccgatg agattatggt taacgggcag attttcgacc
    31921 accaggcgcg cctgcattcg tttgaactgg cgatggatgt taaggaagag ttgttgggat
    31981 agtgtgtctt aacgcgggaa gccttatccg agctggcaac gctgtcctac gtaggactga
    32041 taagcgaagc gcatcaagca ttgtgtaggc agcagaaatg tcggataagg caccgctgat
    32101 tactgataca ccggcagcaa attaaagctc gataaaatat gcaccagtgc gttgccgacg
    32161 ccaaatatca gaatcagcgc aatcatcggc ttgccgcccc agacgcggaa tttcgggctg
    32221 ccaaagcgtt tacgcgatgc gcgggccaac agcgccggta caattgccgc ccagatagta
    32281 gctgctaagc cagcatagcc aatggcgtac aggaatccgt tcgggaacag aagtccccca
    32341 acaacaggcg gggcaaaggt cagcaacgct gttttcaagc ggcccatagc cgagtcatcg
    32401 aaaccaaaca gatctgccag atagtcaaac aaacccagcg ttacgccgag gaacgaactc
    32461 gctaccgcaa agtttgagaa gacgaccagc agcagatcca ggctacggct gttcagcacg
    32521 ccgcttaacg cctgtaccag cacatcaata ttaccgccct tctcggcgat gccgataaac
    32581 tccggacgag ggatgttgcc catcgtcgcc agcaaccaga tggtatacag cgccagcgcc
    32641 atcagcgtac cgtacaccag gcatttcacg atggttttcg gatctttgcc gtaatacttc
    32701 atcaggctcg gcacgttacc gtgataacca aacgatgcca gacagaatgg cagtgtcatc
    32761 agcagatacg gcgcataaga cgcattgctt tcggcgacgt tgaacaatgt cgcaggctgt
    32821 acatgcccca gcaggctgcc gaaggtgagg aagaaagtaa tgactttcgc ccccagcaca
    32881 attgctgtca tccggctgac agctttcgta ctcaaccaca ccacgaacgc taccagcagt
    32941 gcaaaaccaa atccagctgc ccgtgcaggg acgttcagcg acatctccgc gaaggtgtga
    33001 tgcagaatcg aaccgctggc agaaatatag gcgtaagtca ggatatagag cacaaaggca
    33061 atggaaatgc cgttgactac gttccagcct ttgcccagca aatctttggt gatggtgtca
    33121 aagctagaac cgattcgata attcaggtta gcttccagaa tcatcaagcc ggaatgcagc
    33181 atacagaacc aggtaaagat cagcgccgcc attgaccaga agaaccacgc cccggacatg
    33241 accacaggca gagaaaacat ccctgcgcca ataatggtgc cgccgatgat caccacgccg
    33301 ccaagcagcg acggtgacgt ttgggtggtg gttagtgttg ccatgagggc ttctctccag
    33361 tgaaaaatag tgcgactgcg ttgttatgca ctgcactgta ccagtacacg agtacaaaag
    33421 acagaaaaaa agccccgatg gtaaaaatcg gggctgtata tattatttta cagattgtgt
    33481 tcgctgttta gcgaagatta cgcatcacca ccgaaacgac gacgaccggt agagtcatca
    33541 cgacgcggag cgcggccttc acgacgttcg ccgctaaaac gacgaccatc accacgacca
    33601 ccttcacggc gttcaccgct gaagttacga ccgccttcac gacgttcgcc accgaaacca
    33661 cgaccaccgc cacgacgctc accgccagta tgcggctgtg catcgcccag taactgcatg
    33721 ttcatcggct tgttgagaat gcgagtgcgc gtaaagtgtt gcagcacttc acccggcata
    33781 cctttcggca gttcgatggt ggagtgagaa gcaaacagct tgatgttacc aatgtaacgg
    33841 ctgctgatgt caccttcgtt agcaatcgcg ccaacgatat gacgaacttc aacaccatca
    33901 tcgcggccca cttcaatgcg gtacagctgc atatcgccaa catcacgacg ttcacgacgc
    33961 ggacgatctt cacggtcacc acgcgggcca cggtcgttac gatcgcgcgg accacgatca
    34021 tcacggtcac ggaattcacg tttcggacgc atcggcgcat ctggcggaac aatcagagta
    34081 cgttcaccct gtgccatttt cagcagtgcg gcggccagag tttcgagatc cagctcttca
    34141 ccttctgccg tcggctgaat tttgctcagc agtgcacggt attgatccag atcgctgctt
    34201 tccagctgct gctgtacttt agcggcgaat ttttccagac gacgtttgcc cagcagttct
    34261 gcgttcggca gttcaacttc cggaatggtc agcttcatgg tgcgttcaat gttacgcagc
    34321 agacgacgct cacggttctc aacgaacagc agcgcacggc cagcacggcc cgcacgaccg
    34381 gtacgaccga tacggtgaac gtaagactca gaatccatcg ggatatcgta gttaaccacc
    34441 aggctgatac gctcaacgtc caggccacgg gccgcaacgt cggtcgcaat caggatgtcc
    34501 agacgaccgt ctttcaggcg ttccagagtc tgttcacgca gcgcctggtt catgtcaccg
    34561 ttcagcgcgg cgctgttgta gccgttacgc tcaagagctt cagccacttc cagagtcgca
    34621 tttttggtac gaacgaagat aatcgccgca tcaaaatctt ccgcttccag gaaacgtacc
    34681 agtgcttcgt ttttacgcat accccagaca gtccagtagc tctggctgat gtcaggacgg
    34741 gtagtcacgc tggactgaat gcgcacttcc tgcggctctt tcataaagcg gcgggtaatg
    34801 cgacgaatcg cttccggcat ggttgcagag aacagagcgg tctgatgacc ttccgggatc
    34861 tgcgccataa tggtttcaac gtcttcgatg aagcccatgc gcagcatttc gtcagcttca
    34921 tccagaacca gaccgctcag tttagagagg tccagagtgc cacgtttcag gtggtccagc
    34981 agacggcccg gagtaccgac aacgatctgc ggcccctgac gcagggcgcg taattgcacg
    35041 tcataacgct ggccgccgta cagggcaacc acgtttacgc cgcgcatgtg tttagagaaa
    35101 tccgtcattg cttcagcaac ctgtaccgcc agttcgcggg tcggtgccag caccagaatc
    35161 tgtggtgctt tcagctcagg atcaagattc tgcagcagag gtaaagagaa tgctgcagtt
    35221 tttccgctcc ccgtctgggc catacccaga acgtcgcggc cattcagcag atgtggaata
    35281 cactctgcct gaattggaga tggtttttcg taacccagat cgttaagggc ttcaaggata
    35341 ggagccttca ggcccagatc tgcaaaagtg gtttcgaatt cagccatgta gtacgtgtgc
    35401 ctcaaaatta atggcggcca gtctacataa ctcatcatga aattgatcag caattttcat
    35461 tgaaaagtgt gaaccggctc aaagtaggtg tattaacgaa caacaacgcc ctcacccgtt
    35521 aaggtgatgg caatcaaaaa agattacggg ctgatgtgta cgtcagctat tgctggtccg
    35581 attctgccag gtcatcttgg tcctggccca ggagcgataa ttccaacaat gcgtatcggt
    35641 gctcaacaaa gttatgaacg ttgttggcaa ccgccagttt gaacagtgcc gtggcgctgt
    35701 ccaaatcccc cagacttagg tagtacttac ctaaatagaa gttggtttca ctgagatgct
    35761 cagcgagcga ggtgttatcc gttgcgtccg ccttgagcct ttccattaac gtttgttcgc
    35821 taatgttgcc caggtagaac tcgacaatgt tccatcccca ctgttcctta tccgattttt
    35881 cgaagtgctg tttcaacact tctttagcct gcttctcatc gagcttctgc tcggcgagat
    35941 aaagccacag actacggaaa ggatcattgg gatcgtcttg ataaaacgcc agcagatcat
    36001 cttgcgctaa cttgtcacga ccgccgtaat ataatgcgat cccgcgattc aagtgcgcgt
    36061 agttgtaagt tggatcaagc tcaagtacag aatcaaacgc ttcataggca gcatcaaaat
    36121 tgcctgcctg cgttaaatat atgcctaagt aattgaatac ttcaggcata tccggtcgga
    36181 ttgccagcgc ttgcgaaaaa tcgttacgcg ctaatgccct cagaccgaga ctatcataca
    36241 acactccgcg ctcatataaa agctgtgcgc gttcgtcatc ggttaaagcc cgactggcaa
    36301 ggatttgttc catacgtgcc agaatcactt cctgctgtaa agtcggttgc aatggtaccg
    36361 cgaggacttc acttttacgc caggaagtat tactgcatcc tgcaagcgta agtgctgtcg
    36421 caacgaaaca ccagcgcaaa aaaggcttca tttcccactc ccgaagacca cggttgaatg
    36481 aacgtcctgt tcccggttgc taacaaggcg tcctgcccgg ttaaaagccc cccgccgcag
    36541 cggagggcaa atggcaacct tactcgccct gttcagcagc cggagcttcc ggtgctgcag
    36601 caggttgaga ctgctcagtc gcttctttaa tgctcagacg gatacggccc tggcgatcaa
    36661 cttccagaac tttcaccggt acttcctgac ccatctgcag gtaatcggtc actttctcaa
    36721 cgcgtttgtc agcgatctga gagatgtgta ccagaccttc tttaccgccg ccgatggcaa
    36781 caaatgcgcc aaagtcaacg atacgggtca ctttaccatt gtagacgcgg cccacttcga
    36841 tttctgcagt gatctcttcg atacgacgaa tagcatgttt cgctttctcg ccgtcggtcg
    36901 ctgcgatctt cacagtaccg tcatcttcga tttcgatggt ggtgccagtt tcttcggtca
    36961 gggcacggat aacagagccg cctttaccga taacgtcttt gatcttgtcc gggttgatct
    37021 tgatggtatg gatacgcgga gcgaactcag agatatcgcc acgtggcgcg ttgattgcct
    37081 gttccattac gcccaggata tgcagacgcg cacctttagc ctgattcagc gcaacctgca
    37141 tgatctcttt ggtgatacct tcaattttga tatccatctg cagtgcagag ataccgtcgc
    37201 gggaacccgc aactttgaag tccatatcgc ccaggtgatc ttcgtcgccc aaaatgtcag
    37261 acagtacaac gtagttgtcg ccttctttca ccagacccat tgcgataccc gcaacagcag
    37321 ctttgattgg cacacctgcg tccatcagcg ccagggacgc gccgcacacg gaagccatag
    37381 aagaagaacc gttggattcg gtgatttcag acaccacacg tacggtgtac gggaatttgt
    37441 ccatatccgg catgactgcc agcacaccgc gcttcgccag acgaccgtga ccaatttcac
    37501 gacgtttcgg agaaccgacc atgccggttt cgcctacgga gtacggaggg aagttgtagt
    37561 ggaacaggaa ggtgtcagta cgttcgccca tcagttcatc aagaacctgc gcgtcacgtg
    37621 cagtacccag cgttgcggta accagcgcct gggtttcacc acgggtgaac agcgcagaac
    37681 cgtgagtacg cggcagcacg ccagtacgca catccagacc acgaatcata tctttttcac
    37741 gaccgtcgat acgcggttcg cctgccagta cgcggctacg aacaacgttt ttctcgatag
    37801 cgtgcagaat ttcacccagt tcgttttcgt ccagggtttc atcttcagca agcagcgtcg
    37861 cgatggtttc agatttgatg acatcaacct gcgcataacg ctcttgtttg tcggtgatgc
    37921 ggtaagcatc gctcagacga gcttcagcca gtgcagcaac gcgcgcgttc agcgcttcgt
    37981 ttaccggctc cggctgccag tcccaacgcg gtttaccggc ttctttcacc agttcattga
    38041 tgttctgaat aacaacctgc tgttgttcat gaccgaacac tactgcgccc agcatctggt
    38101 cttcgctcag cagttcagct tcagattcaa ccatcagtac agcggcttca gtaccggcaa
    38161 caaccagatc cagtttgctc tctttcagct cgtcctgagt cgggttcagt acgtactggt
    38221 cattgatgta acctacgcgg gcagcaccaa tcggaccatt gaacggaata ccagacagag
    38281 acagtgctgc ggaagcacca atcatcgcga cgatatccgg gttaacctgc gggttaacag
    38341 aaaccacggt ggcgataacc tgaacttcgt tgacgaagcc ttccgggaac agcgggcgaa
    38401 tcgggcggtc aatcagacgc gcgatcaggg tttcgccttc gcttgggcgg ccttcacgac
    38461 ggaagaagct acccgggata cgaccagcag cgtaggtacg ctcctgatag ttaacggtca
    38521 gtgggaagaa gtcctgacct ggtttggctt ttttctgtcc aacaacggta acgaataccg
    38581 cggtgtcatc catgctaacc ataacagcgg cagtagcctg acgagccatc atgccggttt
    38641 ccagagtcac ggtgtgttgg ccgtactgga atttacgaac gatcggatta agcaatgtaa
    38701 tatcctttct ctttcttaga cagtacctta cggcactggt gttaataccc gatcttctgc
    38761 gcatcctcgc gactaatgac aaccctaacc cagcccaatg tgggtaaagc ctctcattag
    38821 ccgcgcgaac ctctgcaacg gaagatcatt catagcaaca atacattagt ttccagtgaa
    38881 ttgctgccgt cagcttgaaa aaaggggcct ctcaggcccc cttttctgaa actcgcaaga
    38941 attagcgacg cagacccagg cgctcgatga gctgggtgta acgtgctacg tctttacgtt
    39001 tcaggtagtc gagcagttta cgacgctgag aaaccatgcg cagcagacca cgacggctgt
    39061 ggtgatcttt tttgtgctct gcaaagtggc cctgcaggtg gttgatctgt gcagtcagca
    39121 gtgctacctg aacttcggta gaaccggtgt cgtttgcgtc acgaccaaac tcagaaacga
    39181 ttttagctgt tgcttcagta cttagagaca ttttaaaact ccaaagtata tagaatgaaa
    39241 ggacgccgat ctctaattca gcgatcccag tgtacgttac gcaaagtgtt aaacaattta
    39301 cgcgacgtta agcggcagta ttctactcgt agcgacctgt tatcgcaaga cggttaacat
    39361 tacgccgggt attcaaccac caggcgacga ggcgcgacgc ggccttcatc gtcaatttcg
    39421 cccataccga taaacttgcc gttctcacct tctgtaacgc gaaccagtcc ttccagcggc
    39481 gcaccggatg tacgaaccgg gttaccattt ttgaagtaaa cagaagacgt taacggaaga
    39541 ttcaccaccg ggtagtccga agctggactg tccattggca tcagtaatgg atcaagtaac
    39601 tccgcggctg gaatatcctg ctgttcggct tgttcaacca gttcacgcag atgttccagg
    39661 gtcaccatcc gttcaaccgg atatttactt accgccagac gacgcaggta aataacatgc
    39721 gcgccacaat cgagtttttc acccaggtca tcaatgatgg tgcggatata ggtcccttta
    39781 gagcaatgaa cttccagctc cagttcattg ccttcatggc gaataaacag caattcataa
    39841 acggtaatcg ggcgtgcttc acgcggaact tcaatgccct gacgcgcata ttcgtacagt
    39901 tttttgccct ggtatttcag tgctgaatac atcgatggga tctgttcgat atcgccacgg
    39961 aaagtatcca gtgccgccgc cagttgctct gtgtcaaagg ttaccggacg ttcttcaacg
    40021 atttgtccat cggcgtcaga cgtatcggta cgctgtccaa gacgcgcaat cacccgatag
    40081 cgtttgtcgg agtccagcag atactgggaa aacttcgtcg cttccccgag gcaaattggc
    40141 aacatgccag ttgccagcgg gtccagcgca ccggtatgcc cggcacggtt ggcgttataa
    40201 atccgtttca ctttttgcag cgcatcattg ctggacatac cctgcggttt atccagcaac
    40261 aaaacgccgt taatgtcgcg accgcgacga cgaggacgac tcattagtcc tccttgctgt
    40321 cgtccgggtt aacacgacgt tcttcgtcat gtttgaccac gctggtcacc aggtttgaca
    40381 tgcgcatccc ttcaaccagc gagttgtcgt agaagaaggt cagttccggc acgatacgca
    40441 ggcgcatcgc tttccccagc aggctgcgga tgaaaccaga agcttcctgc aacgctttga
    40501 tgcccgcttt aaccgcgtct tcatctttgt cgttgaggaa cgttacatat actttggcat
    40561 acgccaggtc gcgagacatt tcgacaccgg aaacggtggt catcatgccc agacgaggat
    40621 ctttaatttc acgctgcagg atgagagcga tctctttttg catttcctgc gctacgcgct
    40681 gcgggcgacc aaattctttc gccataataa attctcctga caaaaaaggg gccatagccc
    40741 cttttaaaat taatctcagg tggaaagggc tgtgtaggcc tgataagacg cgcgagcgcc
    40801 gcatcaggca acggctgccg gatgcggcgt aaaagcctta tccggcctac aacccagaca
    40861 accttaagcg atggtacgtt ggatttcgat gatttcgaat acttcgatca catcgccagt
    40921 gcggacgtcg ttgtagttct taacgccgat accacattcc ataccgttac ggacttcgtt
    40981 aacgtcatct ttgaagcggc gcagggactc cagctcgcct tcgtagataa ccacgttgtc
    41041 gcgcagaacg cggatcgggt tgtgacgttt aaccacacct tcggtaacca tacaacctgc
    41101 gatggaacca aatttcggtg atttgaatac gtcacgaact tccgccagac cgataatctg
    41161 ttgtttcagt tccggagaca gcataccgct cattgccgct ttcacttcgt cgatcaggtt
    41221 atagatgacg gagtagtaac gcagatccag gctttccgct tcaatcactt tacgtgcaga
    41281 ggcatcagca cgtacgttga agccaaccag gatggcgttg gacgccgcag ccagggtagc
    41341 gtcggtttcg gtgataccac ctacgccaga accgatgatc ttcactttaa cttcgtcagt
    41401 agacagtttc agcaaggagt cggagatagc ttccacagaa ccctgtacgt ctgccttcag
    41461 gacgatattc acttcgtgaa cttcgccttc ggtcatgttg gcgaacatgt tctcgagttt
    41521 agatttctgc tgacgcgcca gtttaacttc gcggaattta ccctgacgat agagtgcaac
    41581 ttcacgcgct ttcttctcgt cacgtacaac ggtaacttca tcacccgcag ccggaacgcc
    41641 ggacaggccg aggatttcca ccggaatgga cggacccgct tccagcactt cctgacccag
    41701 ttcgttacgc atcgcacgaa cacgaccgta ttcgaagcca cacagaacga tatcgccctt
    41761 gtgcagagta ccttcacgta ccagaacggt agcaaccgga ccacgacctt tatcgaggaa
    41821 ggattcgata accgcaccgc tcgccatgcc tttacgtacc gctttcagtt ccagaacttc
    41881 cgcctgcagc aggatagcgt ccagcagctc atcgatacca gtacccgctt tcgcagacac
    41941 atgtacgaac tggctttcac cgccccactc ttccggcagg atgccgtact gggagagttc
    42001 gttcttaacg cgatccggat cggcttctgg tttatcgatc ttgttcactg caaccaccac
    42061 cggaacctgc gccgctttcg cgtgctggat tgcttcgatg gtctgcggca ttacgccgtc
    42121 gtcggcagca acaaccagga ctacgatgtc cgttgcctgc gcaccacgag cacgcattga
    42181 agtaaacgcg gcgtgccccg gggtgtccag gaaggtgatc atgccgtttt cagtttcaac
    42241 gtggtatgca ccaatgtgct gggtaatgcc gcccgcttcg ccagaggcca ctttcgttga
    42301 acgaatgtag tccagcagag aggttttacc gtggtcaacg tgacccatga tggtcacaac
    42361 cggcgcgcgc ggttccgccg ctgcccccgt gtcacggtcg ctcattaccg cttcttccag
    42421 ctcgttttca cgacgcagga taactttgtg gcccatctct tcagcaacca gctgtgcggt
    42481 ttcctgatcg ataacctggt tgatggttgc cattgcgccc agtttcatca tcgctttgat
    42541 gacctgagag cctttaacag ccatcttgtt cgccagttcg ccaacggtga tggtttcgcc
    42601 gatcacaacg tcacggttaa cggcctgagc aggcttctgg aagccttgct gcagcgaaga
    42661 acctttacgt tttccgcctt taccgccacg tactgctgcg cgtgcttctt cacgatcagc
    42721 ttttgattca gcgtgtttgt tgcctttctt cggacgcgca gctttcgcgt tacgaccacg
    42781 gccacggccg ccttcgactt cacgatcgct ttcgtcttct gcctggcgag catgttgaga
    42841 agtagtgacg tgataatcgc tggaatcttc agtcggttcc gcgttatcag tccatttgtt
    42901 ttcttccgcc atacgacgtg cttcttcagc aacgcgacgt gcttcttctt cgagtttacg
    42961 acgcgcttct tcttcggctt tacgcttgag ctctgcagct tcctgctcac ggcgggcttt
    43021 ttcagcctgg gcgtttttag tcatatcgtc ttgttgattg ctcactttgt ctttttccgc
    43081 agcttcacgt ttcgcttgtt cagcagcttc acgcttagct tgttctgcgg cctcacgttc
    43141 agctttttgt tgcgcctcac gtttggccga ttcttctgcc tcacgacggg cttgctcttc
    43201 cgcttcacgc tgcgcttgct cttccgcagc aaggcgttca gcctcttgcg gatcgcgttt
    43261 cacaaaggtg cgtttcttgc ggacttcgat ttgtaccgat ttgctttttc caccggtacc
    43321 aggaatgtta agggtgctgc gtgttttacg ttgcagcgtc aatttgtccg ggcctgaatt
    43381 tttctgattc aggtggtcaa tcaaagtctg tttctcttgt gcggacacag agtcgtcagc
    43441 agacttccgg atacctgcat cagcaaattg ctgtaccagg cgttccacgg aggtctgtcg
    43501 ctctgcggcc agcgttttaa tcgttacatc tgtcatgctg ttccttcctg ctacagttta
    43561 ttacgcttcg tcaccgaacc agcaaatatt acgggcagcc ataatcagtg ctccggcttt
    43621 ttcgtcggtc aacccttcga tatcagccag atcatcaatg ccctgttcgg cgagatcttc
    43681 cagcgtacaa acgccacggg cggccagttt gaatgccaaa tcacgatcta tcccttcaag
    43741 gttcagcaga tcgtcagccg gtttgttatc accgaggctt tcttcctggg cctgtgcaat
    43801 ggtggccagt gcatttttag cacgctcgcg cagtgcttca acggtcggct catcaaggcc
    43861 ttcgatttcc aacagctctt tcatcggcac ataggccagt tcttccagcg tcgagaagcc
    43921 ttcttctacc agaacagtcg cgaagtcttc gtcgatgtcg agatatttgg tgaaggtgtc
    43981 gatcgctgcg tgcgcttccg cctgatgctt agcctgcagg tcgtcaacgg tcatcacgtt
    44041 gagttcccaa ccgctcagct gcgaagccag acgcacgttc tgaccattac ggccaatcgc
    44101 ctgcgccagg ttaccggctt caacggcgat atccatggtg tgtttatctt catccaccac
    44161 gatagaagca acgtctgccg gtgccattgc gttaatcacg aactgcgccg ggttatcatc
    44221 ccacaggacg atatcgatac gctcgccgcc cagttcagta gaaaccgcct gaacacgtgc
    44281 gccacgcata cctacgcaag cacctaccgg atcgatacgt ttatcgttgg ttttcaccgc
    44341 gattttcgca cgagaacccg ggtcgcgagc cgctgcttta atttcaatca cttcttcgcc
    44401 gatttctggc acttcaatac ggaacagttc gatcagcatt tccggcttgg aacgagtgac
    44461 gaacaattgc gcaccacgcg cttccgggcg aacggaatag agcacgccac gaacacggtc
    44521 gccagggcgg aagttttcac gcggcagcat atcttcgcgc aggatcacgg cttcagcgtt
    44581 gttgcccaga tccagagaga tgttgtcgcg gtttactttt ttcaccacgc cggtgatgat
    44641 ttcaccttca tgttcacgga actgatcaac caccatcgca cgttcggctt cacgcacttt
    44701 ctgcacgata acctgttttg ccgtctgggt ggtgatacgg tcaaaggtaa cagactcaat
    44761 ctgatcttca acgtaatcgc ccagattcag gctttcatct tcataacgtg cggcttcaag
    44821 ggtgatttcc ttggtcggct gggtgacttc atcaacaact aaccagcgac ggaaggtgtc
    44881 aaaatcaccg cttttgcgat cgatctgtac gcggacgtcg atctcttgtt catatttttt
    44941 ctttgttgct gtcgccagcg cgctttccaa tgcttcgaaa atcttctcgc gaggtagcgc
    45001 cttttcattg gatacggctt caactacagc caaaatttct ttgttcatcg cgggcttttc
    45061 acctcatcca gactattaaa agtggggaac caggttcgcc ttctggatat tactcagcgc
    45121 gaacacttca tctttacctt cgacggtaac tgtgatcatt tcaccgtcta ccgctttgat
    45181 aacgccctgc catttacgac ggttttgtac cgccatgcgg agaaccagag tcacctcttc
    45241 tccgacgaaa cgggcgtagt gttcagccgt gaacagtggg cgatcgagac ccggtgagga
    45301 gacttccagg ttataagcaa cggtgatggg atcttcaaca tccagcacag cacttacctg
    45361 gtggctcaca tcagcacaat catcaacatt gatgccatct tcactatcaa tatagatgcg
    45421 cagtgtggat gtgcgaccgc gaataaattc gatgccaacc agttcaaaac ccagggcctc
    45481 aactggcgca gtaatcatct ctgttaattt ttgctctaat gtggacaagc ccacccccaa
    45541 gacataaaaa aagggcctaa agcccagtta ttctgtagtc agataacaaa aaaccccgat
    45601 aaatcggggc tttatataac tgaaccctat aaccgcaact gcggtctgga gcactttcca
    45661 gaaggatttt ttcaaatccc actacgaagg ccgaagtctt cacagtatat ttgaaaaagg
    45721 actctaaggg aaagtggttg cgggggccgg atttgaaccg acgaccttcg ggttatgagc
    45781 ccgacgagct accaggctgc tccaccccgc gcctgaaacg tggcaaattc tactcgtttt
    45841 gggtaaaaaa tgcaaatact gctgggattt ggtgtaccga gacgggacgt aaaatctgca
    45901 ggcattatag tgatccatgc cacattttgt caacgtttat tgctaatcac gtgaatgaat
    45961 atccggttca ctttcatttg ttgaatactt ttgccttctc ctgctctccc ttaagcgcat
    46021 tattttacaa aaaacacact aaactcttcc tgtctccgat aaaagatgat taaatgaaaa
    46081 ctcatttatt ttgcataaaa attcagtgag agcggaaatc caggctcatc atcagttaat
    46141 taagcagggt gttattttat gacgacgatt ctcaagcatc tcccggtagg tcaacgtatt
    46201 ggtatcgctt tttccggcgg tctggacacc agtgccgcac tgctgtggat gcgacaaaag
    46261 ggagcggttc cttatgcata tactgcaaat ctgggccagc cagacgaaga ggattatgat
    46321 gcgatccctc gtcgtgccat ggaatacggc gcggagaacg cacgtctgat cgactgccgc
    46381 aaacaactgg tggccgaagg tattgccgct attcagtgtg gcgcatttca taacaccacc
    46441 ggcggcctga cctatttcaa cacgacgccg ctgggccgcg ccgtgactgg taccatgctg
    46501 gttgctgcca tgaaagaaga tggcgtgaat atctggggtg acggtagcac ctataaagga
    46561 aacgatatcg aacgtttcta tcgttacggt ctgctgacca atgctgaact gcagatttac
    46621 aaaccgtggc ttgatactga ctttattgat gaactgggcg gccgtcatga gatgtctgaa
    46681 tttatgattg cctgcggttt cgactacaaa atgtctgtcg aaaaagccta ctccacggac
    46741 tccaacatgc ttggtgcaac gcatgaagcg aaggatctgg aatacctcaa ctccagcgtc
    46801 aaaatcgtca atccaattat gggcgtgaag ttttgggatg agagcgtgaa aatcccggca
    46861 gaagaagtca cagtacgctt tgagcaaggt catccggtgg cgctgaacgg taaaaccttt
    46921 agcgacgacg tagaaatgat gctggaagct aaccgcatcg gcggtcgtca cggcctgggc
    46981 atgagcgacc agattgaaaa ccgtatcatc gaagcaaaaa gccgcggcat ttatgaagcc
    47041 cctgggatgg cactgctgca cattgcgtat gaacgtttgt tgaccggtat tcacaacgaa
    47101 gacaccattg agcagtatca cgcgcatggt cgtcagttgg gccgtctgct gtaccaggga
    47161 cgttggtttg actcccaggc gctgatgctg cgggactctc tgcaacgctg ggttgccagc
    47221 cagatcactg gtgaagttac tctggagctg cgccgcggga acgattattc aatcctgaat
    47281 accgtctcag agaacctgac ctacaagcca gagcgtctga cgatggaaaa aggcgactcg
    47341 gtgttctcgc cagatgatcg tatcggtcaa ttgaccatgc gtaacctgga tatcaccgat
    47401 acccgcgaga aacttttcgg ttatgccaaa actggcctcc tctcctcctc tgccgcttca
    47461 ggcgtgccgc aggtggagaa tctggaaaat aaaggccagt aattcgacat caaccctgcc
    47521 cttcaggggt ggggttacct tgcttatcct ctgtaaactc ctttctgagc atcacataat
    47581 cgaaaacatc atggtttgca tccacaaccc gtgagtctcc tttatagtgt gcaatcactt
    47641 cctccagcgt tttcggctgt tccggctttg ttacccccat ccacgcatta ataaggtaat
    47701 tattgtacgc agtggaaaag atatcgtttt ccgttgtacg atcaacgcca tccccaagaa
    47761 cggggctata ccagataaac atcgggacat gatatgcctg ctggctggcc tccctgcctc
    47821 catgaaaata gacgttcttc ttcgtagggt cgcgttccag gccgtggtcg gcaaaataca
    47881 tgaccgaggc gcggcgatct tttaataatt caaaaatctg acctagcaaa ctatctgtgt
    47941 aatgaatgga gttgtcatag caggcatcct gatcgtcctg cggttgaaac acggcgctgg
    48001 attgcggata ggcgctacaa gccggttcat ggcttccatt taaatgaaga acaatcagtt
    48061 tcttttgctg cgtcttttgc tgtaacgctt gcgataaatg cggcaacaac aattcatcaa
    48121 atcctctgac atagactgtt tccatggcgc gcatggcgat actagtaact gctgtaccat
    48181 tctgccgaaa agcggattgc gagcttagcc agaaagtctg aaatcctgct tgattagcca
    48241 tattaataat gttgtccggg taattatgaa tgtcatgact caaaacagaa tcagcagtta
    48301 aagaaagggg aaccgacagc gcagtgtaag gtgcaccgct tattgcttga ttaaacagtt
    48361 tgatctgttt tctttgtgct tcgacttgcg gtgtcgtaga gcgtgtgtat ccatacaaag
    48421 acatattgtc gacacgtaca gactccccca caatcaacac gtaggtatca atacctgtat
    48481 ccctgactga taattgaaaa tatggcaccg tgtttgcaat tgagagtaat ctttgatgct
    48541 ctttcgctgc taaagcaaaa taattgagat tgaaaaacgg cgtataggta gcaaatcgcg
    48601 acgctagtat atatggactg aacgcttttt tattttttgc atctttataa gcaaattgac
    48661 aagcggaaaa taaactgccc gaaatgacaa tcagcaataa tattcctgtc acttttttcg
    48721 tcggcaagga aacatcatat tttattatta ctgccaaaaa aagaagggat aaaaaggcaa
    48781 aagcacatag ataagggata tacatcccca gcattttgac aacttcatcc ggatcactct
    48841 gcagcacact aatcgcaaat ccatcattga aagttgtacc aaaggtacac catgaataga
    48901 ggctaatact catgtctgcc gctgtcagta acacaaatgg tgcggcaaca agcaggcgaa
    48961 gcggaaggga tgatatacgt ttaacaacca ggatggtcag aacgaagaac agcaatcgct
    49021 gaaccatatg cgctccggaa gaggcgacta agttcgtaat accaaaaaca ataacacaaa
    49081 gatacaacaa ccaatgagat ttaaaacttc taacaaattt gttgaatact gtcatccaga
    49141 aatccaagtt cacaaccaat ataaacaatt atcaacaatg ttcaatttta tatcagacat
    49201 gtttttcaac tctgatccat atcagaccga aacactgtta gttttttctt tttaaatgat
    49261 gcggccattg ttctcagtaa ttaaataaca ttatcaatgc gtctctaaac attacgcaga
    49321 acgtagccat cagtagttat actgacagga gcaggatggt ttatcgagaa gtaaacatat
    49381 ccgtattcgt accggaactg gagttgacac aataaagtgc caattatgtc agcagaaggg
    49441 aaaagtttat aactaaggcg taccggcacc atcgtttcaa agtaccagct acgagtaaag
    49501 caactggacg agatacagat acctgacaac cattcctcag atcaggacca aaacgaaaaa
    49561 agacgctttt cagcgtctct tttctggaat ttggtaccga ggacgggact tgaacccgta
    49621 agccctattg ggcactacca cctcaaggta gcgtgtctac caattccacc acctcggcac
    49681 ggatactact ttttagttcg ggatatcgct ggtcggctta gccggagcag ctggctgagt
    49741 ttgttcggtt ttggccggcg cactcaggtt ttcccattcg ctacctttat tggttttgtt
    49801 gctattgatg ttacccagta ccagactgat gatgaagaat aacgttgcca gcagcgccgt
    49861 catgcgggtc atgaagttac cagaaccact tgaaccaaac agcgtagcgg aagcgcctgc
    49921 tgcgaaggag gctcccatat cagcgccttt accttgctgc agcatgatca gaccaacaag
    49981 gccaattgcc acaataagga aaactaccaa aagagcttcg tacataatca acctgttcct
    50041 tgcggagttg ccgcgtacca atgcttcaac caataaagcg ggagttttta atctttccca
    50101 ctgaagcggg tgtgaatact aaccaaagcg aatgaccttc gcaagggcaa ttttatcgca
    50161 ttgtatcaac tgcggaaaaa aacagcaaaa ccgatgtgtt cgccgagaaa aaaggcgaca
    50221 atcgccgcct ttttagccag tcatctaacg ctttaaacgg cttttactgc atcggcgata
    50281 cggtgtgcaa attcagttac ctgcgcttcg tcttcacctt ctaccatcac gcgaattaac
    50341 ggctcggtgc cagatttacg cagcaaaacg cgtccacggc tacccagcgc cgcttcaact
    50401 tctgcggtca cagctttgac tgattcatgc tccagcggat cgccgctacc tgcggtgtaa
    50461 cgcacgttaa ccagaatctg cgggaacatt ttcatgccgc tgcaaaggtc gtgcaggctc
    50521 atatgattac gtgccatcgc cgccagcacc tgcaagccag caacgatgcc gtcaccggta
    50581 gtggttttat ccagcaggat cacatgaccg gagttctctg caccgatacg ccagcctttc
    50641 tcctgcattt tttccagtac gtagcggtca cccactttcg cgcgcgcaaa tggaatacct
    50701 aactgtttca gcgccagttc aagccccatg ttgctcatca atgtacccac cgcgccacca
    50761 cgcagctggc cctgacgaag accttcacgc gcgatgatat acatgatctg atcgccatcg
    50821 actttattgc cttcatggtc aaccataatc acgcgatcgc cgtcgccgtc gaaggcaata
    50881 ccgagatccg ctttttcagc cagcacacga gcctggagcg cgcgaacgtc ggtagccccc
    50941 acttcggcat tgatgtttac accgttcggc tcacaaccga tagcgataac gttcgccccc
    51001 agttcgcgca gcacgttcgg cgcgatgtga taagtcgcac cgtttgcgca atccaccaca
    51061 atcttcagtt cactgaggct aagttcgttc gggaacgtgg ctttgcaaaa ctcgatatag
    51121 cgacccgcag catcaacgat acggctggct ttacccagtt ctgccgaatc aacacagctg
    51181 atctcttttt ccatttccgc ttcgatggct tcttcaactg catccggcag cttagtaccg
    51241 tcaatagaaa agaatttaat gccgttatcg tagaatgggt tatgcgatgc agaaattaca
    51301 atcccggcct ctgcgcggaa ggtacgcgtc agataagcca cggcaggtgt aggcatcggg
    51361 cctgtaaaga gtgcggaaag gcccgcagcc gccagacccg cttccagtgc tgactccagc
    51421 atatagccag aaatacgcgt gtctttacca ataatgatct tacgggagcc gtggcgcgcc
    51481 agcactttac ccgcggccca acccagctta agcacaaaat caggggtgat cggcgcatcc
    51541 cctacacgac cacgaatccc atcggtaccg aaatatttac gattactcat agcgtttgtt
    51601 ttcctttgca gacagagtgg cttccaccac ccgcatcgct tctacggttt ctttgacgtc
    51661 atgaacacga atgatatgcg cgccttgcat agcggcaatg accgcacaag ccagactacc
    51721 gctcagacgc tcagatggcc ccacgttcag caattgccca atcatcgatt ttcgtgacat
    51781 acccaccaac agcggcaggt tgaaatgatg aaattcagcc aggcgcgcca gtaatgaata
    51841 gttatgggag agatttttac cgaaaccgaa tccggggtcg agcaacaatt tctcttttgc
    51901 gatacccgcc tgctcgcaac gtgctatttg ctcaataaag tagcgattca cttctgcaaa
    51961 gacatcgtca tacttcgggg cttcctgcat ggtttttgga tttccctgca tatgcatcag
    52021 acaaaccggt aaaccggttt ctgcagccgc ctccagagcg ccaggttcgg aaagggagcg
    52081 gatatcgtta ataatgtgag cgccaacttt cgctgactca cggatgactt ctggtttgga
    52141 tgtatctacc gagatccaga cttcgaagcg ttgagcaatt gcctcaacca caggaataac
    52201 acgttgcaac tcttcttcaa cgctaacttc cgccgcccct gggcgcgtgg actcaccacc
    52261 aacgtcaatg atcgtcgcgc cagcgttgat catcagattc gcatgtttca ccgcatctat
    52321 cagcgagtta tgcgtgccgc catccgaaaa ggaatcaggc gtgacgttga ggatccccat
    52381 tacgtgagga tggctaaggt ccagtgaagt gccctgggca tagagtttca tggtgttatc
    52441 cctagtatga attgataaga aaaaaccccg gagcacgccc cggggttttc ggtacaaata
    52501 cagtcatctg atgcgggaac ttacttgtcg cctaactgct ctgacatggt gttacccggg
    52561 ttcggcgtac gcggttcatc aaccggacgt ggagcctttg gactaccatt gtcgccagaa
    52621 ttgttagaag cgcctggttc ttcccagccc gctggcggac gtacatcgcg acgtgccatc
    52681 aggtcatcaa tctgcggtgc gtcgatagtc tcatatttca tgagagcatc tttcatcgca
    52741 tgcagaatat ccatattgtc ggtcagaagc tgacgcgcac gattatagtt acgctcaatc
    52801 agtgctttca cttcctggtc gatgatacgt gcagtttcat cggacatatg tttcgctttc
    52861 gctacgctac ggccgaggaa cacttcacct tcttcttccg cgtacagcag tggacccaat
    52921 ttctcagaga agccccactg agtcaccatg ttacgtgcca ggttggtcgc aactttaata
    52981 tcgttggacg caccggtaga aacatgttcc ggcccgtaga tgatctcttc tgccagacga
    53041 ccaccgtaca gcgtagaaat ctggctttcc agtttctgac ggctggcgct gattgcgtcg
    53101 ccctcaggca agaagaaagt cacacccagc gcacgaccgc gtgggataat cgtcactttg
    53161 tgcaccggat cgtgttccgg caccaggcga ccgataatcg cgtgacccgc ttcgtggtaa
    53221 gccgtcgatt ctttctgcgc ttccgtcatc accatggagc gacgttccgc acccatcatg
    53281 attttgtctt tcgctttctc gaactcaacc atcgacacaa cgcgtttgtt gccacgagca
    53341 gcgaacagtg ccgcttcgtt caccaggttc gccaggtcag caccggagaa acctggagta
    53401 ccacgggcaa tgattgccgc gtcgatatcg ggtgccaatg gtacacgacg catgtgaact
    53461 ttcaggatct gctcacgacc gcgaacatct ggcaagccaa ccacaacctg acggtcgaaa
    53521 cggccaggac gcagcagcgc cgggtcgaga acgtccggac ggttagttgc ggcgataacg
    53581 atgatacctt cgttaccttc gaagccatcc atctcaacca gcatctggtt cagagtctgt
    53641 tcacgttcat cgtgaccacc gcccaggcct gcgccacgct ggcggcctac ggcgtcgatt
    53701 tcatcgataa agatgataca cggtgccgct ttcttcgcct gttcgaacat gtcacgaaca
    53761 cgggatgcac ccacaccgac gaacatttcg acgaagtcag aaccggagat agtaaagaac
    53821 ggaactttcg cttcgcctgc aatcgctttc gccagcagcg ttttaccggt acccggagga
    53881 ccgaccatca gaacgccttt cgggatctta ccgccgagtt tctggaagcg gctcggctcg
    53941 cgcagatact caaccagttc agcaacttct tcttttgctt cgtcgcagcc cgcaacgtca
    54001 gcaaaggtcg ttttgatctg atcttcagtc agcatgcgcg ctttgctctt accaaacgac
    54061 atggcacctt tgccaccgcc gccttgcatt tgacgcatga agaagatcca gacaccaatc
    54121 agcaacagca tcgggaacca ggagatgaag atagaagcca gcaggcttgg ttcttcaggc
    54181 ggttcaccga caaccttgac gttcttggtc aacaggttat ccagtaattt cggatcctga
    54241 accggaatgt aagtggtata acggttacta tctttcttgg taacgttgat ttcacgtccg
    54301 ttgatacgcg cttcacgaac ctggtcgtta ttgacctctt gtaggaaggt agagtaatcc
    54361 accttacggc cattagactc gctgggccca aagctctgga atactgacat cagcacaacg
    54421 gcaatgacca gccagagtat taggtttttc gccatgtcac tcaagggatt aacctcttat
    54481 tacaactgtg ttaaaaacag cgtcaggata ctctatatcc agcatctttc aaactttcgt
    54541 ctgaaatctc ccggttaggg tttacgcccg gtcgctacaa tatacacttc ccgcgaacgt
    54601 gcacgagaag agtccggctt acgaactttg accttcgtaa acagggagcg aatttccctt
    54661 agatactcat cgaaaccttc gccctggaac accttcacta caaaactgcc acctggcgct
    54721 aatacatcac gacacatttc tagcgccagt tccaccagat acatggcacg ggggatatcc
    54781 accgccggtg ttccgctcat gtttggtgcc atatcggaca tgacaacctg gactttgctg
    54841 tcgccaacgc gctccagcag tgctttcatc accagttcat cacgaaaatc gccctgaaga
    54901 aagtccacac caacgatagg atccataggt aaaagatcgc aagcgatgat gcggcctttg
    54961 ccgccaattt gggtgaccac atattgtgac caaccacccg gagcagcacc aaggtcgaca
    55021 accgtcattc ccggtttaaa gagtttgtca ctttgctgta tttcatcaag tttaaaccag
    55081 gcacgggaac gtaacccctt tttctgtgcc tgttgaacat atttatcgct aaagtgttcc
    55141 tgaagccagc ggctggagct ggcagaacgc ttcttacctg tcatttaact ttcccatggg
    55201 gataactcat cgtaaccaat tgcgtaaatt tttacgcgcc tatttggtga tatatgggag
    55261 atggcggtag aatgacccgt tttcaatccc aacgtaagca aaaaatacga tgaatctgag
    55321 tactaaacaa aaacagcacc tgaaaggtct ggcacatccg ctcaagccag ttgttctgct
    55381 tggcagtaat ggtttgaccg aaggggtgct ggccgagatt gaacaagcgt tagagcacca
    55441 tgaactcatc aaggtgaaaa tcgccaccga agatcgcgaa actaaaacct tgatcgtgga
    55501 agctatcgtg cgcgaaaccg gcgcctgtaa tgtacaggtc atcggtaaaa cgctggtgct
    55561 ttatcgccca actaaagaac gtaaaatctc gctgccacgc taagattatc ctaaagttac
    55621 acacatttgc tgtgtaaaac gaggggtttt ccgcaggcag gagagcaaaa tgccacgctc
    55681 tgttcgttga taaaaggccg catagcggcc tttttccttt ctttacaata catcaacatc
    55741 ttgagtattg ggtaattctt acaggtattc caccttaatt acttcaaatt ctacttcgcc
    55801 gcccggcgtt ttgatgacca caacatcatc ttcttctttg ccgatcaggc cacgagcaat
    55861 aggcgagttt acagaaatca ggttttgttt aaagtcagct tcgtcatcgc caacgatgcg
    55921 ataagtctgt tcttcgtcag aatcgagatt cagcaccgtt acggtagcac caaaaataac
    55981 gcgcccattg ttgggcattt tggtgacatc aatcacctgc gcgttcgaca gcttggcttc
    56041 gatgtctttg atacggcctt cgcagaagcc ctgctgttca cgagctgcgt ggtattcggc
    56101 gttttctttc aggtcgccat gctcacgcgc ttccgcgata gcagcaatga tttcaggacg
    56161 gcgcacagat ttcagaaaat ccagctcttc gcgtaatttt tcagcgccgc gtaaggtcat
    56221 cggaatagct tgcatttgtt atacctcttg aatattcctg atggggcaag tcttcaccca
    56281 ccccggctgt tcggcctgcc cggcataact cctcaccggg accagaagca aaaaaatacc
    56341 gacccgggta caagtcccag gtcagctaca attcacattt tgatagtcat tttaccctga
    56401 agttcctgaa gggtcatcgt ttactttata gggcgttgcg ccgtagtatg acggctcgat
    56461 tccaggttgt tagcgcgaga ttatgcgatt ttccagattt atcatcggat tgaccagctg
    56521 tatagcgttc agtgttcagg ccgcaaatgt tgatgagtat attactcaac tccccgctgg
    56581 tgccaacctt gccctgatgg tgcaaaaagt cggcgcgtcg gcccccgcta ttgattacca
    56641 cagtcagcag atggcgctgc ccgccagtac gcagaaagtg attacagcgc tagcggcgtt
    56701 gattcaactc ggccccgatt ttcgttttac cacgacgctt gaaaccaaag gtaatgtgga
    56761 aaacggcgta cttaagggtg acttagtggc gcgatttggt gccgatccga cgttaaaacg
    56821 tcaggatatt cgcaatatgg tcgcgacttt gaaaaaatct ggcgtcaacc aaatcgatgg
    56881 caatgtgttg atagatacct ccattttcgc cagccacgat aaagcccccg gctggccatg
    56941 gaatgacatg acacaatgct ttagcgctcc gcctgccgcc gccatagttg accgcaactg
    57001 tttctccgtc tcgctctaca gtgccccaaa acctggtgat atggctttta tacgcgtggc
    57061 atcttattac cccgttacga tgttcagcca ggtacgcacc ctcccccgtg gttctgccga
    57121 agcgcaatac tgcgaactgg atgtcgtacc aggcgacctg aaccgcttta cgctgacggg
    57181 atgcctgccg caacgttctg agccgctccc gttggctttt gccgtgcagg atggagccag
    57241 ctatgccggg gcaattctga aagatgagtt aaaacaggcg ggtatcacct ggagcggaac
    57301 actgctgcgc cagactcagg ttaacgaacc tggaacggta gttgccagta aacagtcggc
    57361 cccgctgcac gatctgctta agattatgct gaaaaagtcg gacaacatga tcgccgatac
    57421 ggttttccgc atgataggcc atgcgcgctt caatgtgcct ggaacatggc gggccgggtc
    57481 ggacgccgtg cgtcagatcc tgcgccagca agccggtgtc gatattggaa acaccattat
    57541 tgccgatggt tcagggcttt cgcggcataa cctgattgcc cccgccacca tgatgcaggt
    57601 gctgcaatac attgcccaac acgacaatga acttaacttt atctccatgc tgccgctggc
    57661 gggctatgac ggctctttgc agtaccgtgc aggtctgcat caggcgggcg tggatggcaa
    57721 agtctcagcg aaaaccggtt cgttgcaggg ggtatataac ctggcgggat tcattaccac
    57781 agcgagcggg caacgaatgg catttgtaca atatctttct ggctatgcag tagaacccgc
    57841 ggatcagcgt aatcgccgta ttccgttagt gcgttttgaa agccgtttgt acaaagatat
    57901 ttatcagaac aattagtcaa aaagaaaccc cggcgcatgg ccggggtttt gctgattaac
    57961 gcttgtaaat gaactcaacg ccttcttcgt cgtcttcgtc ccaatcgtca tcccagtctt
    58021 catcatcctc ttcagcaatc tcttcaagct gctggcggtg ataatcatcc cacatgaatt
    58081 cgactttctc tggctgtttc gcttcttcag cctgcacgac cgggttttca atgataaagg
    58141 tcatcacatc ccagcagaga tctttcacgc ccagtccgct cgccgcagag atcagataat
    58201 atttatcttc ccagcccaac gcttcagcga tcgctttcgc tttctcttcg gcttctgcct
    58261 tatccagcag atcgatcttg ttgaagacta accaacgcgg tttcgccgcc agatcctggc
    58321 tgtatttttc cagctcgctg ataataatac gcgcgttttc aaccggatcg gtgccgtcaa
    58381 tcggatcgat atcgatgagg tgcaacagga cgcggcaacg ttccaggtgc ttcaggaagc
    58441 gaatgcccag acctgcgcct tccgcagcgc cttcaatcag tcctggaata tcggcaacaa
    58501 cgaagctctt ttcgttgtcc attcgtacca cacccagact tggcaccaga gtggtaaacg
    58561 gataatccgc cactttcggt ttagccgccg ataccgcgcg aataaaggtc gatttacccg
    58621 cgtttggcat ccccaacata ccgacgtcag ccagcagcat cagctccagc agcagctcac
    58681 gcttatcgcc cggcgtaccg ttagttttct gccgtggtgt acggttaact gacgatttga
    58741 aacgggtatt gcccagaccg tgccagccgc ccttggcaac cagcagacgc tgaccgtgtt
    58801 tggtcatatc gcccatggtt tcaccggtac cctggtcgat aacacgcgta cctaccggca
    58861 ctttaatcgt cacgtcttta ccgcgcttac cggtacagtc gcggcttgcg ccattctgac
    58921 cacgctctgc gcggaaagat ttttcaaaac gataatcgat aagcgtgttc aggttctcgt
    58981 cggcttccat ccatacgtca ccgccgtcac cgccgtcgcc gccatccggg ccgcctttcg
    59041 gaatatactt ttcgcggcgg aagctcacgc aaccattacc gccatcacct gcaacgacca
    59101 gaatcgatgc ttcatcaaca aacttcattt tattctccgt aaatcattcg cctgcgcggg
    59161 gttgcgatac caccgttgta tgcttacgta atccgcccca aatacgatga ccaatggcgg
    59221 aatacatcgc gcccgcaacc acgacaaacg caccgagata acctaaaagg tttaacatcg
    59281 gtctggcgaa gaaatcgggc caggccagtg ataaaagatc tgaaaaaaac agcgtaaaca
    59341 gtggggtgag cgtaatgatc gcgctcacct gcgctgcctg ccagcgagcc atcgcttccg
    59401 ccagggcgcc atatcctacc aatgtattca gtccgcaaaa aattaaacat gcgagctgcc
    59461 agtggctaag ctgcgctatc actccaggct ttgccagagg gaagagcgca attgtacata
    59521 aagtgtacag taaaaacaga atctgcggtg aggccagccg acgcaataaa accttttgcg
    59581 ccacgccata actcacccaa accgtcgcag caccgacccc aaagataact ccccaggtgt
    59641 aatcggtgag ctttgtaaat atctcgacca gactggtgtt aaaaaacatc accaggccgc
    59701 tcaggagcat caatgcccct acaacctgag tgctgcgcat tttctctttc aggataaata
    59761 cgctggcaac catcatgcca actggcgaga gttgcccaat cacctgcgaa gcggtcggac
    59821 tcaggtattg caaggatgag ctgaacagga tgaagttccc aaacagcccg gcggtcgcca
    59881 ctgccaacaa aatcaaccag cgtggcttac gaaacacgcg taatggcggc aacctcttct
    59941 tcaccgcaag aatggcacca aggccaatac tcgccatcaa gaaacggtaa aacacgattg
    60001 tcggaggttc catcacctcc agcacctgct tcattgcgat tggcaacgcc ccccagcaaa
    60061 ttgctgtggt gagcgccaaa agaatgccaa tgcctgcctg ctgcttcata ccgtattccc
    60121 tgcaaagcgc atttgcgaat taacgtcgca ccatgcgcat ttttaccggt tatcgaatgt
    60181 aaaaagcccc gcaacgtgtt gcggggcttt catccgttac cgggacgcga aaaacttatt
    60241 cagcttcgat gctgataaat ttacggtttt tcgggccttt aacttcgaat ttcactttac
    60301 cgtctgcttt agcaaacaga gtgtggtcac gaccgcaacc tacgttagcg ccagcgtgga
    60361 atttggtacc acgttgacga acgatgatgc tacccgccag aacggattcg ccaccgaaac
    60421 gcttaacgcc caggcgttta gcttctgaat cgcgaccgtt acgtgtggag ccgccagcct
    60481 ttttatgtgc catttgaaat ctctcctcag gtcttaggcg ctgatgccag taattttcac
    60541 atcagtgaac cactgacgat ggccctgctg cttacgatag tgtttacgac gacgaaactt
    60601 aacgatttta actttctcgc cacgaccgtg agcaacaact tcagctttga ttacgccgcc
    60661 atcaacgaaa ggaacgccga ttttgacttc ttcaccgttt gcgatcatca gcacttcagc
    60721 gaactcaaca gtttcgccag ttgcgatgtc cagcttttcc aggcgaacgg tctgaccttc
    60781 gcttactcgg tgttgtttac caccactttg gaaaaccgcg tacatataaa actccgcttc
    60841 cgcgcacacc ttttcaatga ttcagagtgc gctataaata ttcacaatag ggcgcgaata
    60901 ttacgcaaaa cgcacgcctt tgacaagtgc tacagtcaat acacgaagaa aaaaaacaca
    60961 acttgtacgg taacgtttat ctgtgccatt ttttcagtac aatcacccta tattcctaac
    61021 cataaaccct aagttgcctt tgttcacagt aaggtaatcg gggcgaaaag cccggctttt
    61081 gcgatgaatt tagaaaaaat caatgagtta accgcgcaag atatggcggg tgttaatgcg
    61141 gcaatccttg agcagcttaa ttccgacgtc caactgatca atcagttagg ctattacatc
    61201 gtcagcggcg gcggtaaacg tattcgtccg atgattgctg tactggctgc acgagctgtt
    61261 ggctatgagg gaaatgcgca tgtcaccatt gctgccctga tcgagtttat ccacacggcg
    61321 actctgctgc acgacgacgt tgtggatgaa tcagatatgc gcaggggtaa agctaccgcc
    61381 aacgccgcat ttggcaatgc cgccagcgtg ctggtaggcg attttattta tacccgcgcg
    61441 ttccagatga tgaccagcct cggctcgctc aaagtgctgg aagtcatgtc agaagccgta
    61501 aacgtcatcg cagaaggtga agttctgcaa ctgatgaacg ttaacgatcc ggacatcact
    61561 gaagaaaact acatgcgcgt tatctatagc aaaaccgcgc gtctgtttga ggctgccgcg
    61621 cagtgttccg gtattctggc tggctgtacg ccggaggagg agaaaggcct gcaggattat
    61681 gggcgctatc tcggcactgc tttccagttg atcgacgatt tactcgatta caatgccgat
    61741 ggcgaacagt taggtaaaaa cgtcggcgac gatctgaacg aaggtaaacc gacgctgccg
    61801 ctgctgcatg caatgcatca tggcacacca gaacaggcac agatgattcg taccgccatc
    61861 gaacagggta acggtcgcca tcttctggaa ccggttctgg aagcaatgaa cgcttgtgga
    61921 tctcttgaat ggacgcgtca gcgtgccgag gaagaagcag acaaagccat cgcagcgtta
    61981 caggtgctcc cggacacccc gtggcgagaa gcactcatcg gcctcgcgca catcgctgtt
    62041 caacgcgatc gttaatcccc tccccgcatc ccgcgcagtg cgtgggatga ttccaataag
    62101 ttccataaaa acacttattc agctctatag cacctgaaaa atagggctgt acatctttat
    62161 atattctgaa tattcacact ctttacagga actttttaga gcaataggcc atcaggagta
    62221 tagtgatgct cgacagaaga agtgttctga atgaaagcga ctaacttaag gagtgaggaa
    62281 agatggaaag taatttcatt gactggcatc ccgctgacat cattgcgggt ttgcgcaaga
    62341 agggaacgtc aatggcggcg gaatctcgca gaaatggttt gagttcctca acgctggcga
    62401 acgcattatc gcgcccctgg ccgaaaggag agatgattat tgcgaaagcc ctgggaactg
    62461 acccctggat tatctggcca tctcgctacc atgatccgca gacccatgag tttatcgaca
    62521 gaacacagtt gatgcgtagc tacactaaac cgaaaaaatg agtggtctgg cggtagcccc
    62581 gcgaacgggg ctgccagctc tcagacaatt actcgccttt cacacgctca atatttgcac
    62641 ctaaagcgcg cagtttgtct tcaatgcgtt cgtagccacg atcgatgtga taaatacgat
    62701 caactaccgt cgtcccttcc gcaatacagc cagccagcac caggcttgct gatgcacgca
    62761 gatcggttgc cataacctgt gcgccagaaa gtttttcaac accgtgacaa ataacggtat
    62821 tgctttcgat ttcggcgtgc gcgcccatac ggctcagctc tggcacatgc ataaagcggt
    62881 tttcaaagac cgtttcggtg atgaagccgg tcccttctgc caccaggttc aacagcgtga
    62941 actgggcctg catatcggtc gggaatgccg gatgcggcgc ggtacgtacg ttaacagcct
    63001 tcggacgttt gccatgcata tccaggctaa tccagtcttc gccgacttcg atgtctgctc
    63061 cagcgtcacg cagtttcgcc agcacggcgt cgagagtatc tggctgcgcg ttacggcaga
    63121 taattttgcc gcgagagatc gccgccgcca ccaggaaagt accggtttcg atacgatccg
    63181 gtagcacgcg atagacaccg ccgcctaaac gttccacacc ttcgatgacg atacgatcgg
    63241 tgccctgacc gctaattttc gcacccagcg taatcaggaa gttcgcagta tcgacgattt
    63301 ccggttcacg cgctgcgttt tcaataatcg tggtgccttc cgccagggtt gcagcacaca
    63361 tgatggtcac cgttgcgcca acgctgactt tatccatcac gatatgtgcg cctttcagac
    63421 gaccatcgac ggaagcttta acgtaacctt cttccagttt gatggtcgcg cctaattgtt
    63481 cgaggccaga aatgtgtaga tcaaccggac gtgcaccgat cgtacaaccg ccaggcagtg
    63541 aaacttgccc ctgaccaaag cgcgctacca gcggccccag tgcccagata gaagcacgca
    63601 tggttttaac cagatcgtaa ggtgcgcaga atacattaac gtcgcgggca tcaatatgca
    63661 cagaaccatt acgttctact ttcgcaccca gctggcttag cagcttcatt gatgtatcga
    63721 cgtctttcag tttcgggacg ttctggatct ctaccggttc ttccgccagt agtgcggcaa
    63781 aaaggatagg cagagcagca tttttagcgc cggaaattgt gacttcgccc tggagcttcg
    63841 ttggcccctg aacacgaaat ttatccattt agtttgttct cagttaacaa ttcatatccg
    63901 ctaccggcga atcgcccata gctcaaaagc cgttcagttt gcgatcgcgc gcccactccg
    63961 caggggtata cgctttgatc gacacagcat gaatgcggtt atccgcaata tattccatca
    64021 gcgggccata gaccgtctgc tgttttttaa cccgactcat gccgtcaaac aactcaccca
    64081 cggcaataac ctgaaagtgg ctgccatcgc cggaaacgtg gacttcctgg agggagagag
    64141 cgttcatcaa cacgctctga atttcattat tttccatggg atcttcaatc atcagttaat
    64201 aaaccagcga aacatcttag agcaaagttg cgctggcata aataagcaaa aagcctcgct
    64261 gataaatcag acaaggctcg acttgcaggc aggtttgccg gacaggcggt taacgccata
    64321 tccggcctga aaaaatttaa cgaggcagaa catcagcagg caaattatac aatttcgcca
    64381 gggtatacac tttatcgttt accccctgaa gcgtcacgtt gttgccctgc tttttcgcca
    64441 gatcgataag atggagcagc agtgccagtc cacccgtatc cacgcgggac acacggctaa
    64501 gatcgatgca ggtaatcccc ttcaccgctt cctcacgcat ttcccaaagc ggtagcagaa
    64561 cgtcctgatc cagctctccg gatagcgcca gcgtgtcacc cgtctgcatc cagctcagtg
    64621 actcgctcat tattttttct cttccagagt gattttctgt tgagaaatcg atttcagttg
    64681 cgcagtcagg ccgtcgatac ctttggtacg cagcagcgtt ccccactcgt tttgtttggt
    64741 ggtgatcata ctgacgcctt cagcaatcat gtcgtaagcc tgccagttgc ccgtctggga
    64801 gtttttacgc cactggaagt ccagacgcac cggcgggcga ccattcgggt caataatggt
    64861 aacgcgaata ggcacaatgg ttttatcacc cagcggctgt tctggcgcaa tctgataggt
    64921 ttgaccgtga tacatcgcca gcgcctgacc gtaagcctgc ttcaggtact cacggaaagc
    64981 ggcaaagtag gcttcacgtt gagctggggt cgcactcttg taatactggc ccagcaccag
    65041 cgcaccggcg tatttcacct gtacgtatgg cagcagttcc tgatcgacaa tggtacgcag
    65101 ataatccggg ttggcccgaa tttgcggttg ctcattcttc aggcgatcga acgttttctg
    65161 cgccgcctcg tccatcagct tatacggatt ggtctggtct gccgcggttg ccgcactcag
    65221 cggtgcaatc accagcaaag cgaccatcat taaacgttta aacatgcgtc ggttctcctg
    65281 aaattatttc gttgtaccca caggttcagt ggtttcatta ttacctggcg cagcagctgg
    65341 cgcatcgcca ctattcttat tgtcatcgcc tttactaccg taaaggaact gaccaataag
    65401 atcttccagc accatcgcag acttggtgtc ctgaattgta tcgccatcct tcaggatagc
    65461 agtccccagt tccgggtctt caaaaccgac gtttaatgcc agatattgtt cccccagcag
    65521 gccggaagta cgaatgctca gcgaactggt atcaggaatg tggttataac gttgttcaat
    65581 ttccagcgtt acgcgcggca gataggtttt cgggtccagc gtaatatccg ccacccggcc
    65641 cacaacaaca ccaccaatgc tgaccggaga gcgcgctttc aggccgccaa tgttatcgaa
    65701 cgtcgcataa agcgtgtagg tcggttcagt acgtatggac gtcacgttcg ccgccttcag
    65761 gcaaacaaac agcgccgcca gtagtgctgc taataaaaag atacccaccc aaatttcatt
    65821 ttttttcgtt tgcatgaact caattcccaa acatcaatgc ggtcagcaca aaatccagcc
    65881 ccagaacagc cagagacgag tggacaacgg tgcgagtggt tgcccggcta atcccggcag
    65941 acgtcgggat ggcgtcgtag ccgttaaaca acgaaatcca cgtcaccgtg atggcgaaca
    66001 ccacgctctt aatcagacag ttgaccagat ccatacgcca gtcgacggca ttttgcattg
    66061 ccgaccagaa gaacccgcta tcaatgcctt tccaactgac gccgaccaga gatccgcccc
    66121 agatccccac ggcgacgaaa ataaccgtca acagtggtaa tgaaataacc ccagcccaga
    66181 aacggggaga aataacccga cgcagcggat ccaccgccat catctccata ctggagagtt
    66241 gctctgtagc gcgcatcagg ccgatttctg cggttagcgc cgaaccagca cgcccggcaa
    66301 acaacaacgc ggcaaccacc ggccccagtt cacgcagtag cgataacgcc accagcatac
    66361 ccagactggt ttccgcacta taagtggtca gaaccagata accttgcagc cccaacacca
    66421 ttccgatgaa cacgccagaa actacaataa tcagcatcga caggacgccg acattataga
    66481 gctggcgcac cagcagcggc gcatgtttgc gaaattccgg tttgccgacc agcgcattga
    66541 ataacattaa cccggcccgc ccgaacgttc tcagggtttt aatcccttta tgtccgagcg
    66601 acgccagcgc atttaacagc atgagtggct taactccctg gtaaaagatc agcgtgataa
    66661 tcgccggcag gatagcggaa cggaacaggc ccgtcagcta tcccgtccag aaactgacgt
    66721 acgcgtggat caggattcgc ctgcaacgcc tgggcactgc catgagcgac aatttttttg
    66781 tccgccagga tccaggcgtg atcggcaata cttaacactt ccggcacatc gtgagaaacc
    66841 accacacaag tcacacccag cgcgctgttc agctcagaaa tcagcttcac cagtacgccc
    66901 atggtgatgg gatcttgccc aacaaagggt tcatcaaaca tgatgagatc cggctccagc
    66961 gcaatcgcac gcgccagcgc tgcacgccgc gccatcccac cggaaagttc agaaggcatt
    67021 agtttagccg ctccacgcag ccccacggcc tccagcttca tcatcaccgt actatgcaac
    67081 aatggcgcgg gaagttgagt atgttcgcgc agtggatagg cgacgttgtc aaatacgttc
    67141 atatcagtga acaacgcccc ggactgaaat aacatgctca tccgtttgcg cactgtatac
    67201 aggcgcgaac gagacatcgc cggaatattc tcaccatcga aaagaatctc accatgatct
    67261 ggtgcgattt gcccgccaat cagacggagt agcgtcgttt taccgatgcc cgatggcccc
    67321 atgatcgccg tgatcttccc tcgcggcacg gtcagggaaa tattatcgaa gatgcagcga
    67381 ttgccacgcg taaaactgac atcgcgcata tcgactaaat tcgccacaga ctgctccata
    67441 attcaccctt cgtcttgcgt tgattttcta agcatggcgc tcaatttaac cttgaaccca
    67501 acatatttac agaatattac ccgccgtggt tagcgaaagc tggcatttgt tttacttttt
    67561 agccgcataa agtcaaaatt aagaatccgt tacggctttc tgaaaatctt cagcggaccg
    67621 gcgagtatac ctgaagaaag gacgttagat gcttttagct acggcactgt taattgttgg
    67681 tttacttttg gtcgtttaca gtgccgaccg cctggttttt gccgcgtcta ttctttgccg
    67741 aacctttggc atcccgccgc tgatcatcgg catgacggtg gtcagtattg gtacatcgtt
    67801 accagaaatc atcgtctcgc ttgccgcgtc tctgcacgaa caacgcgatt tagccgttgg
    67861 tacagccctc ggctcaaaca ttatcaatat attgctgatc ctcggtctgg ctgcgctggt
    67921 tcgtcctttt accgtccatt ctgatgttct acgccgtgaa ttacccttaa tgttgttggt
    67981 cagcgtggtg gccggttccg tactctatga cggacaactt agtcgcagcg atggtatctt
    68041 tctcctcttt ctggctgtgc tatggctgct gttcattgtt aaacttgcac gtcaggctga
    68101 acgtcagggg actgacagcc tgaccagaga gcagcttgca gagctgcctc gtgacggcgg
    68161 attgcccgtc gcgtttttat ggctcggcat tgcgcttatc atcatgccag tggccacgcg
    68221 gatggtggtt gataacgcca cggtgctggc gaattacttt gccatcagcg agttgacgat
    68281 gggtctgacg gcaattgcta tcggaaccag cctgccggaa ctggcaaccg caatagcggg
    68341 ggttcgcaaa ggtgaaaacg acattgctgt cggaaatatc attggcgcaa acatttttaa
    68401 tattgtcatc gtgttgggtt tacccgcgct gataacgcca ggagagattg atccactggc
    68461 gtacagtcgt gactacagcg tgatgttgct ggtgagcatt atttttgcgt tgctgtgctg
    68521 gcggcgctcc ccgcaatcgg gccgtggtgt aggggtatta ttaacaggcg gatttatcgt
    68581 atggctggcg atgttgtact ggttatcgcc aatactcgtt gaataactgg aaacgcatta
    68641 tgtcgcacgt agagttacaa ccgggttttg actttcagca agcaggtaaa gaagtcctgg
    68701 cgattgaacg tgaatgcctg gcggagcttg atcaatacat caatcagaat ttcacgcttg
    68761 cctgtgaaaa gatgttctgg tgtaaaggga aagttgtcgt catggggatg ggaaaatcgg
    68821 ggcatattgg gcgaaaaatg gcggcaacgt ttgccagcac cggtacacct tcatttttcg
    68881 tccatcctgg tgaagccgcg catggtgatt taggcatggt taccccacag gatgtggtga
    68941 ttgctatctc taactctggt gaatccagcg aaatcacggc cttaattcca gtgcttaagc
    69001 gtcttcacgt accgttaatc tgcatcaccg gtcgcccgga gagcagcatg gcgcgcgccg
    69061 cagatgtgca tctgtgtgtt aaagtagcga aagaagcctg tccgttaggg ctggcaccga
    69121 ccagcagcac caccgccacg ctggttatgg gcgatgccct cgctgtcgcg ctgttaaaag
    69181 cacgcggctt tactgctgaa gattttgcgc tctcacaccc aggcggcgca ctgggtcgta
    69241 aacttctgct gcgcgtaaac gatattatgc atacgggcga tgagatcccg catgttaaga
    69301 aaacggccag tctgcgtgac gcgttgctgg aagttacccg caaaaatctt ggtatgactg
    69361 tcatttgcga tgacaatatg atgattgaag gcatctttac cgacggtgat ttacgccgtg
    69421 tcttcgatat gggcgtggat gttcgtcagt taagtattgc cgatgtgatg acgccggggg
    69481 gaatacgtgt gcgccctggc attctggccg ttgaggcact gaacttaatg cagtcccgcc
    69541 atatcacctc cgtgatggtt gccgatggcg accatttact cggtgtgtta catatgcatg
    69601 atttactgcg tgcaggcgta gtgtaaagat tcaaggataa acaacaatga gcaaagcagg
    69661 tgcgtcgctt gcgacctgtt acggccctgt cagcgccgac gttatagcaa aagcagagaa
    69721 cattcgtctg ctgatcctcg atgtcgatgg cgtactgtca gatggcctga tttatatggg
    69781 caataatggc gaagagctga aagcgttcaa tgttcgtgac ggttatggca ttcgttgtgc
    69841 gctcacctct gatattgaag tcgctatcat taccgggcga aaggctaaac tggtagaaga
    69901 tcgttgtgcc acattgggga tcactcactt gtatcagggg cagtcaaaca aactgatcgc
    69961 ctttagcgat ctgctggaaa aactggcgat tgccccggaa aatgtggctt atgtcggcga
    70021 tgatctcatc gactggccgg taatggaaaa agtgggttta agcgtcgccg tggccgatgc
    70081 gcatccactg ttgatcccgc gcgccgatta cgtgacgcgc attgctggcg gtcgtggcgc
    70141 agtgcgcgaa gtttgcgact tattactcct ggcgcagggc aaactggatg aagccaaagg
    70201 gcaatcgata tgagtaaagc cagacgttgg gttatcattg tgctatcact ggcggttctg
    70261 gtgatgatcg gcattaatat ggccgaaaaa gacgataccg cccaggtggt cgtcaacaac
    70321 aatgatccca cctataaaag cgagcatacg gacacgctcg tctataaccc agaaggggca
    70381 ctaagctatc gattgattgc tcaacacgtt gaatattatt ccgatcaggc cgtttcgtgg
    70441 tttacgcagc cggtacttac cacgtttgat aaggataaaa tcccgacatg gtccgtaaaa
    70501 gcagataaag ccaagctgac caatgaccgg atgctctatt tatatggaca cgttgaagtc
    70561 aacgcacttg tgccagactc tcaacttcgc agaatcacga cggataacgc gcagatcaat
    70621 ctggtgacgc aggatgttac ctctgaagac ctcgtcacgt tatacggaac aacatttaac
    70681 tccagcggtc tgaaaatgcg cggcaactta cgcagcaaga acgccgagct gattgaaaag
    70741 gttagaacat cctatgaaat tcaaaacaaa caaactcagc cttaatcttg tgcttgccag
    70801 ctcacttctg gccgccagca ttccggcatt tgccgtaacc ggagacactg atcagccgat
    70861 ccacattgaa tcggaccagc aatctcttga tatgcaaggc aacgtggtta cctttaccgg
    70921 taatgtcatc gtcacccagg gcaccatcaa aattaatgcc gacaaagtgg tcgttacccg
    70981 tccgggcggc gaacaaggta aagaagtgat tgacggctac ggtaaaccgg caacgttcta
    71041 ccagatgcag gacaacggta aacccgttga aggtcacgct tcccagatgc actacgaact
    71101 ggcaaaagat tttgtcgttc tgacgggtaa tgcttatctg cagcaggtcg atagcaacat
    71161 taagggcgat aagatcactt acctggtgaa agagcagaaa atgcaggctt tcagcgacaa
    71221 aggcaagcgc gtaacaaccg ttctggtgcc gtcgcagctg caggacaaaa acaacaaagg
    71281 ccagaccccg gcacagaaga agggtaatta attcgttatg gcaacattaa ctgcaaagaa
    71341 ccttgcaaaa gcctataaag gccgtcgcgt ggtagaagac gtcagcctga ccgtcaactc
    71401 cggggaaatt gtcggtctgc tggggccaaa cggtgccggt aagaccacca ctttctacat
    71461 ggttgtaggc attgtgccgc gcgatgcggg caacatcatt attgatgatg acgatatcag
    71521 tctgctgcct ctgcatgcac gcgcgcgccg cggtatcggc tatctgccac aggaagcctc
    71581 cattttccgt cgcctcagcg tttacgataa cctgatggcg gtactgcaaa ttcgtgacga
    71641 cttgtctgct gaacaacgtg aagaccgcgc gaacgagctg atggaagagt ttcacattga
    71701 gcacctgcgt gacagcatgg ggcagtcact ctccgggggt gaacgtcgcc gtgtagaaat
    71761 tgcccgcgca ctggctgcga atccgaaatt tattctgctc gacgaaccgt ttgccggggt
    71821 tgacccgatc tcggttatcg acattaaacg catcattgag cacctgcgcg acagcggcct
    71881 gggcgtgctg atcactgacc acaacgtgcg tgaaacactg gcggtttgtg aacgcgctta
    71941 tatcgtcagt caggggcatt tgatcgccca cggcacgcct acagaaatct tacaagacga
    72001 acacgttaag cgtgtatacc ttggggaaga cttcagactc tgatagggta gaagtttgcg
    72061 acgttttagc aggagagtac gattctgaac atgaagcaag gtttgcaact caggcttagc
    72121 caacaactgg cgatgacgcc acagctccaa caggcaattc gtctgttgca gttgtcgacg
    72181 ctggaacttc agcaggagct acagcaggcg ctggagagta atccgctgct tgagcaaatc
    72241 gacactcatg aagaaatcga cacccgcgaa acgcaagaca gtgaaacgct ggacaccgcc
    72301 gacgcgctcg aacaaaaaga gatgccggaa gagctgccgc tcgatgccag ttgggacacc
    72361 atttacaccg ctggtacacc atccggcacc agcggtgact acattgacga cgagctgccg
    72421 gtctaccagg gcgaaacgac gcagaccttg caggattacc tgatgtggca ggttgagctg
    72481 acaccgtttt ccgacactga ccgcgctatt gctacctcta tcgtcgatgc cgttgatgaa
    72541 accggttatc tgactgtccc gctggaagat attctcgaaa gtataggcga tgaagagatc
    72601 gacatcgacg aagttgaagc cgtccttaag cggatccaac ggtttgatcc ggtcggtgtg
    72661 gcggcaaaag atctgcgtga ctgtctgctg atccaactct cccaattcga taagaccacg
    72721 ccgtggctgg aagaggccag actgatcatt agcgatcatc tcgatctgtt agccaatcac
    72781 gacttccgca ctttaatgcg cgtcacgcgt ctgaaagaag atgtgctgaa agaagccgtc
    72841 aatctgatcc agtcgctcga tccgcgcccc gggcagtcga tccagactgg cgaacctgag
    72901 tatgtcattc cagatgtgct ggtgcgtaag cataacggtc actggacggt agaactcaac
    72961 agtgacagca ttccgcgtct gcaaatcaac cagcactacg cctcgatgtg caataacgcg
    73021 cgcaacgatg gtgacagcca gtttatccgc agcaatctgc aggatgccaa atggttgatc
    73081 aagagtctgg aaagccgtaa cgatacgcta ctgcgcgtga gtcgctgtat cgttgaacag
    73141 cagcaagcct tctttgagca aggtgaagaa tatatgaaac cgatggtact ggccgatatc
    73201 gcccaggctg tcgaaatgca tgaatcgacg atatctcgcg tgaccacgca aaaatacctg
    73261 catagtccac gaggcatttt tgaactgaag tatttctttt ccagtcacgt caataccgag
    73321 ggcggcggcg aagcttcctc cacggcgatt cgtgcgctgg tgaagaaatt aatcgcggcg
    73381 gaaaacccag cgaaaccgtt gagcgacagc aagttaacct ctttgctgtc ggaacaaggt
    73441 atcatggtgg cacgccgcac tgttgcgaag taccgagagt ctttatccat tccgccgtca
    73501 aaccagcgta aacaactcgt ttgacccaac cgataaggaa gacactatgc agctcaacat
    73561 taccggaaat aacgtcgaga tcaccgaggc actgcgcgaa tttgttacag ccaaatttgc
    73621 caaacttgag caatattttg accgaatcaa ccaggtctat gttgttctga aagtggagaa
    73681 agtcacccac acctcagatg caacactgca tgtaaacggt ggtgaaattc atgccagcgc
    73741 ggaaggtcag gacatgtacg ctgccattga tggcttaatt gataagctgg cacgccagtt
    73801 gaccaaacat aaagataaac tgaaacaaca ctaattgtcc gggcaattag catgtgcatg
    73861 gcggtctgtt gtgcggcaca acgggccatt tgtacggtta atgctccgag cctgttccac
    73921 tgtttgagtg ggcaggttct taggtgaaat tatgacaaat aatgatacaa ctctacagct
    73981 tagcagtgtt cttaacaggg aatgtacgcg aagccgcgtc cactgtcaga gcaaaaaacg
    74041 cgccctggaa atcatcagcg agctggcggc gaaacaactt agcctgccgc ctcaggtggt
    74101 ttttgaagct atcctgacgc gggaaaaaat gggcagtacc ggtatcggca atggtattgc
    74161 cattccgcat ggcaaactgg aagaagatac tctgcgcgcc gttggcgttt tcgttcagct
    74221 cgaaacgcct atagctttcg atgccatcga caaccaaccg gtggacttac tttttgccct
    74281 gctggtgccg gcagaccaaa ctaaaacgca cctgcatact ctgtcgctgg tggcgaaacg
    74341 tctggcggac aaaaccatct gccgccgttt acgcgcagcc cagagcgatg aagagctgta
    74401 tcaaatcatt acggataccg aaggtactcc ggatgaagcg tagttattcg gtaatgtctc
    74461 ttttagacgt tgtgaggaga aacagtacat ggtactgatg atcgtcagcg gacgttcagg
    74521 ttcaggtaaa tctgtcgccc tgcgtgcgct ggaagatatg ggtttttact gcgtggataa
    74581 ccttcccgta gtgttgttac ccgatctggc tcgaaccctg gccgatcgcg agatttctgc
    74641 cgccgtcagc attgatgttc gtaatatgcc ggagtcacca gaaatattcg aacaggcgat
    74701 gagtaacctg cctgacgctt tctcaccgca actcctgttc ctggatgccg accgtaatac
    74761 cttaattcgt cgttacagtg acacgcgccg actgcatccg ctttccagca aaaacctgtc
    74821 gctggaaagt gctatcgaca aagaaagcga tttgctggag cctctgcgtt cgcgagcgga
    74881 tctgattgtc gatacctcag aaatgtccgt tcacgagctg gctgaaatgc tgcgtacccg
    74941 tctgctgggt aaacgtgaac gcgaactgac catggtcttt gagtctttcg gcttcaaaca
    75001 cggtatccct atcgatgcag attacgtctt tgacgtgcgc ttcttgccga acccgcactg
    75061 ggatccgaaa ctgcgtccaa tgacaggtct tgataaacct gtcgccgcgt tcctcgaccg
    75121 ccacacagaa gtacacaatt ttatctacca gacgcgaagc tatcttgagc tatggttacc
    75181 tatgctggaa accaacaacc gtagctactt gacggtcgcc attggttgta ccggcgggaa
    75241 gcaccgttcg gtgtatattg cagagcaact ggcagactac ttccgctcgc gcggtaaaaa
    75301 cgtccagtca cgccatcgta cgctggaaaa acgtaaacca tgaccgtcaa gcaaactgtt
    75361 gaaatcacaa acaagctggg catgcatgcc cggcctgcaa tgaagctgtt tgaattaatg
    75421 cagggttttg acgctgaagt gctcttacgt aatgacgaag gcaccgaggc tgaagccaac
    75481 agcgttattg cgctgctgat gttggattct gccaaaggac ggcagattga agttgaagcg
    75541 accggtccac aggaagagga agcactggcc gccgttatcg ccctctttaa ttctggtttt
    75601 gatgaagatt aatcttcatc actttgacat acaactccct tcaaactccc cccgacaata
    75661 agaaaatcac gtactgaaat cgttctcaat caacgtcatt tgtacatttt gtgcgctttt
    75721 cactttcaga agaaccttaa gaaaacctta agaggcattg tttaggtttt gtttaagtta
    75781 atcgaccata ctggagatcg tcagaaaata tttccaggag atggcatgat tcgcttatct
    75841 gaacaaagtc ccctgggcac cggaagacat cggaaatgtt atgcgcatcc ggaagatgcc
    75901 caacgctgta tcaagattgt ctaccatcgt ggcgatggtg gcgataaaga gatccgccgt
    75961 gagttaaagt actacgcgca tcttggtcgc cggttaaaag actggagtgg aataccgcgc
    76021 tatcacggta ccgttgagac ggattgcgga accggttatg tctacgatgt gattgcagat
    76081 tttgacggca agccttccat tacgctgacc gaatttgctg aacaatgccg ttacgaagaa
    76141 gacattgcac aactgcgcca gctactgaaa cagctgaagc gttatttgca ggataaccgt
    76201 atcgtgacga tgtcgctgaa gccgcagaat atcctctgtc accgcatcag tgagtcagag
    76261 gttatcccgg tcgtctgcga caacattggt gaaagcacat tgattccact ggcgacctgg
    76321 tcgaagtggt gttgtctgcg taagcaagag cggttatgga aacgatttat cgcccaaccg
    76381 gcgctggcta ttgccctgca gaaagatctg caacctcgtg agagcaaaac gctggccctc
    76441 acttcgcgcg aagcttaatc cagctggtgt tgttgcataa acggctcacc gcctaactga
    76501 tacatctgcc gtaaaatcca cgcctgacgg ctacgcacgt agcccgatgg cgaggagact
    76561 ttgaaacgaa gtggattagg taatacagct gccagtaatg cagcttccga ccgggtaagt
    76621 ttgctcgcgg gtttgtggaa ataacgttgt gccgcagctt cgacgccaaa cacaccgtcg
    76681 ccaaattcgg cgatattcag gtaaaccgtc aggatacgct ttttgctcca gaccgtttct
    76741 atccccagcg ttaatccggc ttccagccct tttcgaaccc agctacgccc atcccataaa
    76801 aagagatttt tggctgtctg ttgagaaatc gttgaagcac cgcgaatacg gttttcattg
    76861 cgctcgttgt gcgccagggc tttctcaatg gaagcgacat caaagcccca gtgctcagga
    76921 aatttctgat cttctgcggc aatcaccgcc agtcccatcc acggcgagat ttgatccata
    76981 ctgacccagt cagaatgtgc cacgtaacga aaattgccat gcagccaggc gctgacctgt
    77041 cgctcgacca ttaccgctga gaagggaaca ggcgcaacgc taaacaacgc gatgcccccg
    77101 ccccagaaaa cggcgaggac aaccattaac cgcaaaagaa aacggcgaac gaaactaaac
    77161 accgttaagc ggcttttact cattcagcca gaaccagcac gcgggaaacc agcttatcaa
    77221 tgccgctcgc cgcttctgca atgttctgcg ccagcatata tgctggggtg gtgacaatct
    77281 tattgtcttc atcaaccacg atatcatcga caggacacgg cacatgctcc gcgcccatct
    77341 cttccagcac ttctgcggta tcgatatcag taccgatggt caaacgcagc gggaaatcga
    77401 aaattttcgg cagcatcgcc ggggcaatac acataaaacc aagcggtttt ccggcctgat
    77461 gcatcgcttg tgccagcgcc tttaattcac ggtcaacggt gcattcgcta ccaagactgg
    77521 caaaattgct taaattcttc gccgcgccaa acccccccgg cacaatcaac gcatccagtt
    77581 cagcggcatc ggcctgggcc agaggacgga tttcaccgcg cgttattcgt gccgcttcaa
    77641 tcagcacatt gcgcgtttcc gtcatcgctt cgccagttaa atggttgata acatcaacct
    77701 gctgcttatc cggtgcaaag cagaccgcct gcgcaccgct gcgtgaaata gctaacaacg
    77761 tcaacaccgc ttcatgaatt tcagaaccgt catagacgcc gcatccgctc agaattacgc
    77821 caattttctt cattgtgatc atcctttcgc aattgactga aacacattaa tttttttaat
    77881 aaaaatggta cgcatcacac atttaactga ttcatgtaac aaatcattta agttttgcta
    77941 tcttaactgc gtgcggcctg aaaaacagtg ctgtgccctt gtaactcatc ataataattt
    78001 acggcgcagc caagatttcc ctggtgttgg cgcagtattc gcgcaccccg gtctagccgg
    78061 ggtcattttt tagtggcttt tgccacccac gctttcagca cttctacgtc gtgacgccac
    78121 tcttctttca tctcttcaat ccattcaccg acgttatctt cccaggccgg aaggtcagga
    78181 gactgaattt gctgacccag ctgttgcaga tggcgtaacc ccactgaccc cgccgcacct
    78241 ttaattttat gtccttcctc aacaatgcct tttttatcct gcgccgtcag attcgactcc
    78301 agcacgctga catagcccgg catcatcttc tcaaacaccg ctaacccgtc ggtgatcagc
    78361 ttcggtccta caagttcgag atactgttcc agcatgggaa tatcgagcaa tgcttctgat
    78421 ttactgttct cttctgtcgt caccgtactc tcctcatcat cctgggtatc ccagaatttc
    78481 ttgatcatcg cggttagcgc cggaacagaa agcggcttac tcagcacatc atccattcca
    78541 gcattgaggt actcttgttt gtctttcagc acgttagcgg ttaaggccac cagcggcggt
    78601 aaatcctcgc gcggataacg tttcgtcagt tcacgagaga tatccagccc ggtcatatct
    78661 ggcaactgaa tatccagcaa caccaggtcg tattcgcccg gtttaaacat ctccagcgcc
    78721 gccttgccgg tcatggcgac atcaacgctg ttacctaatt tttccagcac agaacgcgca
    78781 acaatcacgt tcagttcaat gtcttccacc agcagcacat tcagcgccgg taaaggcata
    78841 tcgtcttcat caaacgcatc atcgacctct tctgctaccg acggtgcgtg gatcgtcaac
    78901 gtaaaggttg aacctttgcc ctgttcgctg gtaaccgtaa tatcgccgcc catatttttc
    78961 gccagacgac gagaaacggc cagaccaata ccggtgccgg tggcaggttt accgccatga
    79021 ctgtctttca cctggtaata catggcgaaa attttatcca gctcatcctg cggaatgccg
    79081 ataccagagt cttccacttc aaaatgcagc atatcgcctt catcgtagcg cacgcgcacg
    79141 gtaacctggc cttgctgggt gaatttgacg gcgttactga tgaggttcca caggatctgc
    79201 cgtaaacgcg tcccgtcggt aatgacctga tgcggtaatg gcagcgtcgg ctccaggtta
    79261 aagcgcaatc ctttttgttg cgcctgcaat gcggagagat tttccagatc ggcaaggaag
    79321 ctggtgaaat caaccggttg attatcaagc tggaccttgc gccgttccat cttatccatg
    79381 tcgataatat cgttaaagat attccccagc gtgacggccg aaacatggat ggtcttgaga
    79441 tatttttcct gctcggcggt gagttcggta tccagcagaa tgcggctcag accgacgata
    79501 ccgttcagcg gtgtacgcaa ttcgtgactg atggtggaga taaacgtcgt tttgtcgcgg
    79561 ctggcccgtt caagcgcatc ctgataccgc ttacgctcgg taatgtcgcg accaaagccc
    79621 atcaaaccgt gacgtttacc cacgcggtcg tagtacggca ctttacggat ttcaaagcag
    79681 gctttgcgcc cgtccgggta atccagccac tgttcatagg tcagtgacac attatgacgg
    79741 aacacttttt catcggtttc aatgactttt gcggcggctt ccggtgagta aacatcagca
    79801 ggtttcaggt gaaccagttg tttttcgctt tttccggtca gcagctccat cgcgcggtta
    79861 cagccggaaa actctttatc ttcgttacga taaaaaacca ggtcgggtga agcatcaagg
    79921 aaggaacgta agaatgagga ttgctgctcg agctgaattt gtgtctcttc gcgctctttg
    79981 atttcaattt tcagttggcc gaaggtttcc tgcagttctg cttccgcttt ttcacgaacg
    80041 gcaatttcct gatttagctg ggcaatatta tcttttaact gaacgttgag gctcaaatcg
    80101 cgctcgcgca tctcctccag tttttgcacc agccgtgaca gacgttgtcg tgactcctcc
    80161 agttgctcga cgaccaccga tagaaagtag accgcccacg gcgtaatcag caaaccaaag
    80221 aagatagaac gaataacatc aatgctttcg acctgaccat gcagcaccat ggttaccgcc
    80281 atttgtacca caatggcaag aacgacgagg gccagcgcca gcaacattga gaagcgcacc
    80341 agacctaact tcatcatcag gtcaacataa tactgcgcca gcagacgaat ttgcttcatt
    80401 agggaattcc ttcacgacaa cctgccccaa taatacccaa ttctgacagt tacgttataa
    80461 attgtgtgag aaatgcggaa ttcccctcaa cgacctactc cgttggaggt agccacggac
    80521 gtcccagcgc cgatccctgt acgccatgtt cattcagata gcgatccagc tcgaccattc
    80581 ccgtccatcg attttcgcac cacagcggag caagcagcgt cgggcgacgg gcgctggcgg
    80641 aaatgcggtg gtagatcact tccggtggcg tatggcgaat catttctccg gcagtgagcg
    80701 tgtaatcctc cagttcaata ccgttcaaac gccccgcttc ccaggctttc gccataatgc
    80761 tgcctttcac aatatgcagc ggatgcagct ttatgccgtc cacgccggtt tcaaccactc
    80821 gctccagcgt ttgcaaacat tcagcctgcc cttcgccagg caggccgaca attaagtggg
    80881 aacacacctt cagcccgcgc tgacgtgcca gctgggttgt acgctgataa caggcaaaat
    80941 catggccgcg gttgatgcga tgcagtgttt tgtcgtgggc ggtttgtagc cccagctcca
    81001 gccacacttc gtaaccctgg tccttatatt cgcaaagcag atccagcacc gcatccggca
    81061 cgcagtccgg gcgggtaccc acacacaaac cgacaatatt ggcctggctc accgcctgct
    81121 gatacataga acgcagcacc tgaacttccg caaaggtgct ggtatacgcc tgaaagtagg
    81181 ccagatagcg tttagcgcgg ttaactaaat tcgcctggtg cgccagttgc tcggcaatgg
    81241 aacgatgctg ctgcgcttca tcggcaaacg aggcaacatt acagaatgtg cagccaccac
    81301 gcccgatggt accgtcacgg ttagggcagc taaaaccgcc gtgcagcgtc agcttatgca
    81361 ccttttgccc ataacgacgg gtgagatcac caccaaacat attgactaat ttctgtaact
    81421 gcataatctg atagaccgcg ccttgaaaag aggccaaagc ctgccatttt tagctcaatt
    81481 cggcgatgac ctggatcaat cgtcccggcc tgcttttatc aaccgcataa tcaatcaaaa
    81541 ttaccgaaat ttcatgcata atcacataaa tcacttttgc ttatcttgtg tcagattttt
    81601 ttatctcctg atggatttta ggcaaaaaca gtagcatgaa acgtcattac caattaaggc
    81661 agtataaaat gctggttttg tcgtcagttc aaggcaggat aagggttaac acacctttat
    81721 gacagtcagg aattgactgt ttctctaacg acttcccttt tagccttaaa gataaaatcc
    81781 attttaattt cagtcattta ataaagaatt ttgcgctaaa gcacatttct gtaccaataa
    81841 gcttgccatt tgacctgtat cagctttccc gataagttgg aaatccgctg gaagctttct
    81901 ggatgagcag cctgctcatc atatttatgc agtaattgag atcccctctt caccgtatta
    81961 accgatgcga aaaggacaac aagggggcga atgcgaggcg cgcgtatgac acgcaaaccc
    82021 cgtcgccacg ctctttctgt gcccgtgcgc agcggttcgg aagtggggtt cccgcagagc
    82081 ctgggggagg ttcacgatat gttgtacgat aaatcccttg agagggataa ctgtggtttc
    82141 ggcctgatcg cccacataga aggcgaacct agccacaagg tagtgcgtac tgcaatacac
    82201 gcactggccc gcatgcagca ccgtggcgcg attctcgccg atggtaaaac cggcgacggt
    82261 tgcggcttgc tgttacaaaa accggatcgc ttttttcgca tcgttgcgca ggagcgcggc
    82321 tggcgtttag caaaaaacta cgctgtcggg atgctcttcc tgaataaaga tcctgaactc
    82381 gccgctgccg cacgccgcat cgttgaagaa gaactgcaac gcgaaacctt gtcgattgtg
    82441 ggctggcgtg atgtccccac taacgaaggc gtgctgggtg aaatcgccct ctcctctctg
    82501 ccacgcattg agcaaatttt tgtgaacgcc ccggcaggct ggcgtccacg cgatatggag
    82561 cgccgtctgt ttatcgcccg ccgccgcatt gaaaagcgtc tcgaagccga caaagacttc
    82621 tacgtctgta gcctgtcgaa tctggtgaac atctataaag gtctgtgtat gccgacggat
    82681 ctgccgcgct tttatctgga tcttgcggac ctgcgtctgg aatcggccat ttgcctgttc
    82741 caccagcgct tctccactaa caccgtaccg cgctggccgc tggcgcaacc gttccgctat
    82801 ctggcgcata acggtgaaat caacaccatc accggtaacc gccaatgggc gcgtgcgcgt
    82861 acttataaat tccagacacc gcttatccct gacctgcacg acgccgcacc gttcgtcaac
    82921 gaaaccggct ctgactccag ttcgatggat aacatgctgg aactgctgct ggcaggcggg
    82981 atggatatca tccgcgccat gcgtctatta gtaccacccg cctggcagaa caacccggat
    83041 atggacccgg aactgcgtgc cttctttgac tttaactcca tgcatatgga gccgtgggat
    83101 ggcccggcgg gcatcgtgat gtccgacggt cgttttgccg cctgtaacct cgaccgtaac
    83161 ggtctgcgtc cggcgcgcta cgtcatcacc aaagataagc tcatcacctg cgcctctgaa
    83221 gtcggtatct gggattacca gcctgacgaa gtggtcgaaa aaggccgcgt cgggccaggc
    83281 gaactgatgg ttatcgacac ccgcagtggg cgtattctgc actcggcaga aaccgatgac
    83341 gatctgaaaa gccgccatcc atataaagag tggatggaga aaaacgtccg ccgactggta
    83401 ccgtttgaag atctgtccga tgaagaagtg ggtagccgcg aactggacga cgacacgctt
    83461 gccagctacc agaaacagtt taactacagc gcggaagagc tggactccgt aattcgcgta
    83521 ctgggcgaaa acggtcagga agcggtcggt tcgatgggcg atgatacccc attcgccgtg
    83581 ctctccagtc agccgcgcat tatttacgac tacttccgcc agcagtttgc ccaggtgact
    83641 aacccgccaa tcgacccgct gcgtgaagcg catgttatgt cgctcgccac cagtatcggt
    83701 cgtgaaatga acgtcttttg cgaagcagag ggccaggcgc accgtttaag ttttaaatcg
    83761 ccgattctgc tctactccga tttcaaacag ctcacgacga tgaaagagga gcactaccgc
    83821 gcagatacgc tggatatcac ctttgacgtc actaaaacca cgctcgaagc gacagtcaaa
    83881 gagctgtgcg acaaagccga aaaaatggta cgtagcggca ccgtgctgct ggtgctctcc
    83941 gaccggaata tcgctaaaga tcgcctgccg gttccagccc cgatggcggt tggcgcgatc
    84001 cagacccgtc tggtcgatca aagcctgcgt tgcgatgcca acatcatcgt cgaaaccgcc
    84061 agcgcccgcg atccgcacca cttcgccgtg ttgctgggct tcggcgcgac ggctatttat
    84121 ccataccttg cctatgaaac gctgggccgc ctgatagaca cccatgcgat tgccaaagat
    84181 tatcgtaccg tgatgctcaa ctaccgtaac ggcatcaaca aaggcttgta caaaatcatg
    84241 tccaaaatgg gcatctccac catcgcctct taccgctgct cgaaactgtt tgaagcggtc
    84301 ggtctacacg atgatgtagt gggcctgtgc ttccaggggg cggtcagccg cattggtgga
    84361 gcaagctttg aagacttcca gcaggatctg ctgaatctgt cgaaacgtgc ctggctggcg
    84421 cgtaagccca tcagccaggg cggtctgctg aaatacgtcc acggcggcga ataccacgcc
    84481 tacaacccgg acgtggtgcg cacgctgcaa caagcggtac aaagcggcga gtacagcgac
    84541 tatcaggaat acgcgaagct ggttaatgag cgtccggcaa ccacgctgcg cgatctgctg
    84601 gcaattacgc cgggtgaaaa cgcggtcaac attgctgatg ttgaaccggc aagcgaactg
    84661 tttaaacgct ttgataccgc cgcgatgtct atcggcgcgt taagcccgga agcccacgag
    84721 gcgctggcgg aagcgatgaa cagcatcggc ggtaattcga actccggtga aggcggcgaa
    84781 gacccggcgc gctacggcac caacaaagtg tcgcgcatca agcaggtggc ttccggtcgc
    84841 tttggggtta ctccggcgta tctggtcaat gccgacgtca ttcagattaa agtcgcccag
    84901 ggcgcgaagc caggcgaagg cggtcagttg ccgggtgata aagtcacgcc ttacatcgcc
    84961 aaactgcgct attcggtgcc cggagtgacg ctgatctccc cgccgccgca ccacgatatc
    85021 tactctatcg aggacttagc gcagctcatt ttcgacctca agcaggttaa cccgaaagcg
    85081 atgatctccg tgaagctggt ttccgaaccg ggagtaggca ccatcgcgac tggcgtggca
    85141 aaagcttatg cggacttgat caccatcgca ggctatgacg gcggcaccgg cgcaagtccg
    85201 ctttcatcgg tgaaatacgc aggctgtccg tgggagctgg ggcttgttga aacccagcag
    85261 gcgctggttg ctaacggctt gcgtcacaag atccgtttgc aggtcgatgg cggcctgaaa
    85321 acgggtgtcg atatcatcaa ggcggcgatt ctcggcgcag aaagcttcgg cttcggcact
    85381 ggcccgatgg tggcgctcgg ctgtaaatat ctacgtattt gccatctgaa caactgcgca
    85441 acgggtgtag caactcagga tgacaaactg cgtaagaacc actatcacgg cctgccattc
    85501 aaggtgacga attactttga gtttatcgcc cgtgaaaccc gcgagctgat ggcacagctt
    85561 ggcgtaacac gtctggtgga tctgattggt cgcaccgacc tgctgaaaga gctggacggt
    85621 ttcaccgcca aacagcagaa gctggcgctg tcgaagctgc tggagactgc cgaaccgcat
    85681 ccaggtaagg cactctactg caccgaaaac aacccgccgt ttgataacgg cctgctgaac
    85741 gcgcagttgc tgcaacaggc gaaaccgttt gtcgatgagc gccagagcaa aaccttctgg
    85801 ttcgatattc gcaacaccga ccgttctgtc ggcgcgtcgc tttcaggcta tatcgcccag
    85861 acgcacggcg atcaggggct ggcagccgat cctatcaaag cgtacttcaa cggcaccgca
    85921 ggccagagct tcggcgtgtg gaacgcgggc ggcgtggaac tgtacctgac cggtgatgcc
    85981 aacgactatg tcggtaaagg catggcgggc ggcttaatcg ccattcgtcc tccggttggt
    86041 tccgccttcc gcagccatga agcaagcatt atcggcaaca cctgcctgta tggcgcgacc
    86101 ggtggtcgtc tgtatgccgc aggccgcgcg ggtgaacgtt tcggcgtgcg taactccggt
    86161 gctatcaccg tggtagaagg cattggcgac aacggttgtg aatatatgac gggtggtatc
    86221 gtctgcattc tgggtaaaac cggcgttaac ttcggtgcgg gcatgaccgg cggtttcgct
    86281 tacgttctcg atgaaagcgg cgatttccgc aaacgcgtta acccggaact ggtcgaggtc
    86341 ttaagcgttg acgctctggc gatccatgaa gagcatctgc gtggtcttat caccgagcat
    86401 gtgcagcata ccggctctca gcgcggtgaa gagattctgg cgaactggtc aaccttcgcc
    86461 actaaatttg cgctggttaa accgaagtcc agtgatgtaa aagcactgct gggtcaccgt
    86521 agtcgtagcg cagctgagtt gcgcgtgcag gcgcagtaag gggtagcaac aatgagtcag
    86581 aatgtttatc aatttatcga cctgcagcgc gttgatccgc caaagaaacc gctgaagatc
    86641 cgcaaaattg agtttgttga aatttacgag ccgttttccg aaggccaggc caaagcgcag
    86701 gctgaccgct gcctgtcgtg cggcaaccca tactgcgagt ggaaatgccc ggtacacaac
    86761 tacatcccga actggctgaa gctcgccaac gaggggcgta tttttgaagc ggcggaactg
    86821 tcgcaccaga ccaacaccct gccggaagtt tgcggacgag tctgcccgca agaccgtctg
    86881 tgcgaaggtt cctgcactct gaacgatgag tttggcgcgg tgaccatcgg caacattgag
    86941 cgctatatca acgataaagc gttcgagatg ggctggcgtc cggatatgtc tggtgtgaaa
    87001 cagaccggta aaaaagtggc gattatcggc gcaggcccgg caggtctggc gtgtgcggat
    87061 gtcctgacgc gtaacggcgt aaaagccgtt gtcttcgacc gtcatccaga aattggcggg
    87121 ctgctgacct tcggtattcc ggccttcaag ctggaaaaag aggtaatgac gcgtcgccgt
    87181 gaaatcttca ccggcatggg tattgaattc aaactcaata ccgaagtggg ccgcgacgta
    87241 cagctggacg atctgctgag tgattacgat gccgtgttcc ttggcgtcgg gacttatcag
    87301 tcaatgcgcg gcgggctgga aaacgaagac gccgatggcg tgtacgcagc gctgccgttc
    87361 ctcatcgcca acaccaaaca gttaatgggc tttggtgaaa cccgcgacga accgttcgtc
    87421 agcatggaag gcaaacgcgt ggtggtcctt ggcggtggcg acactgcgat ggactgcgtg
    87481 cgtacgtccg tgcgccaggg agcgaagcac gttacctgtg cctatcgtcg tgatgaagag
    87541 aacatgccgg gttcccgccg cgaagtgaaa aacgcgcggg aagaaggcgt agagttcaaa
    87601 ttcaacgtcc agccgctggg tattgaagtg aacggtaacg gcaaagtcag cggcgtaaaa
    87661 atggtgcgta ccgaaatggg cgaaccggac gccaaaggcc gtcgccgcgc ggagatcgtt
    87721 gcaggttccg aacatatcgt tccggcagat gcggtgatca tggcgtttgg tttccgtcca
    87781 cacaacatgg aatggctggc aaaacacagc gtcgagctgg attcacaagg ccgcatcatc
    87841 gccccggaag gcagcgacaa cgccttccag accagcaacc cgaaaatctt tgctggcggc
    87901 gatatcgtcc gtggttccga tctggtggtg accgctattg ccgaaggtcg taaggcggca
    87961 gacggtatta tgaactggct ggaagtttaa gcgaggtaac aatgaattcg ccagactgtg
    88021 tctggcgaat caaattactg acgaagtgcg cgttgttttc tggcaaatgc ggcatgagcg
    88081 tttgaccttt cctataatag ggataatttt caataaattg tgctttgttc accaagtctg
    88141 atgagtgaag cacatcaagc aatttctcat ttacaatccg tctcaattac ttgttaacac
    88201 ctctgacaat accgattctg caa
//
LOCUS       DACAOP010000005        88118 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.005, whole genome shotgun sequence.
ACCESSION   DACAOP010000005 DACAOP010000000
VERSION     DACAOP010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 88118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88118
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.005"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(11..556)
                     /gene="hemG"
                     /locus_tag="IT892_000359"
     CDS             complement(11..556)
                     /gene="hemG"
                     /locus_tag="IT892_000359"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HAP3133609.1"
                     /translation="MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQ
                     WENYDRVVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQTN
                     SYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTD
                     WEQVANFAREIAHLTDKPTLK"
     gene            complement(568..2019)
                     /gene="trkH"
                     /locus_tag="IT892_000360"
     CDS             complement(568..2019)
                     /gene="trkH"
                     /locus_tag="IT892_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkH"
                     /protein_id="HAP3133610.1"
                     /translation="MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFF
                     VALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAF
                     FESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
                     YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATI
                     AIGGFSTHDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRM
                     FIGVQFTLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAGFTTDSIARWPLFLP
                     VLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPER
                     ILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSM
                     NPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE"
     gene            complement(2058..2672)
                     /locus_tag="IT892_000361"
     CDS             complement(2058..2672)
                     /locus_tag="IT892_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418290.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HAP3133611.1"
                     /translation="MESWLIPAAPVTVVEEIKKSRFITMLAHTDGVEAAKAFVESVRA
                     EHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRY
                     YGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYHQLTGIEALLGQCDG
                     KIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE"
     gene            complement(2672..4003)
                     /gene="pepQ"
                     /locus_tag="IT892_000362"
     CDS             complement(2672..4003)
                     /gene="pepQ"
                     /locus_tag="IT892_000362"
                     /EC_number="3.4.13.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidase"
                     /protein_id="HAP3133612.1"
                     /translation="MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLD
                     DHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTE
                     DVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRS
                     FKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIV
                     ALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKD
                     VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMP
                     HGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIES
                     LLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA"
     gene            4193..6382
                     /gene="fadB"
                     /locus_tag="IT892_000363"
     CDS             4193..6382
                     /gene="fadB"
                     /locus_tag="IT892_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001490315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadB"
                     /protein_id="HAP3133613.1"
                     /translation="MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIG
                     VLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLP
                     VPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGA
                     DSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAKAVLRQAINGDLDWKAKRQPK
                     LEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKS
                     FVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAW
                     KGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDR
                     VDIVVEAVVENPKVKKAVLAETEQKVRQDTVLASNTSTIPISELANALERPENFCGMH
                     FFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFA
                     GFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQK
                     DYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSE
                     EEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAK
                     YLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA"
     gene            6392..7555
                     /gene="fadA"
                     /locus_tag="IT892_000364"
     CDS             6392..7555
                     /gene="fadA"
                     /locus_tag="IT892_000364"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadA"
                     /protein_id="HAP3133614.1"
                     /translation="MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPA
                     LEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAA
                     RMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGI
                     SREMQDAFAARSHARAWAATQSAAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEA
                     LATLRPAFDPVNGMVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCD
                     PSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLIEQIDEKINL
                     NGGAIALGHPLGCSGARISTTLLNLMERKDVQFGLATMCIGLGQGIATVFERV"
     gene            complement(7838..8539)
                     /gene="fre"
                     /locus_tag="IT892_000365"
     CDS             complement(7838..8539)
                     /gene="fre"
                     /locus_tag="IT892_000365"
                     /EC_number="1.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-flavin reductase"
                     /protein_id="HAP3133615.1"
                     /translation="MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDER
                     DKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDE
                     ERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHP
                     GLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSER
                     NAREDRLFGDAFAFI"
     gene            complement(8585..10078)
                     /gene="ubiD"
                     /locus_tag="IT892_000366"
     CDS             complement(8585..10078)
                     /gene="ubiD"
                     /locus_tag="IT892_000366"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HAP3133616.1"
                     /translation="MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLR
                     AGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPK
                     GFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLIT
                     WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVS
                     VALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGY
                     IEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGV
                     ALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQF
                     MYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
                     MGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA"
     gene            10245..10733
                     /gene="rfaH"
                     /locus_tag="IT892_000367"
     CDS             10245..10733
                     /gene="rfaH"
                     /locus_tag="IT892_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="HAP3133617.1"
                     /translation="MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRT
                     AVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGASPAIVPSAVIHQLSVYKPK
                     DIVDPATPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFR
                     KL"
     gene            complement(10730..11512)
                     /gene="tatD"
                     /locus_tag="IT892_000368"
     CDS             complement(10730..11512)
                     /gene="tatD"
                     /locus_tag="IT892_000368"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' ssDNA/RNA exonuclease TatD"
                     /protein_id="HAP3133618.1"
                     /translation="MFDIGVNLTSSQFAKDRDDVVACAFDAGVNGLLITGTNLRESQQ
                     AQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNFST
                     PEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREE
                     MQACVAHGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSS
                     RRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF"
     gene            complement(11554..12330)
                     /gene="tatC"
                     /locus_tag="IT892_000369"
     CDS             complement(11554..12330)
                     /gene="tatC"
                     /locus_tag="IT892_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatC"
                     /protein_id="HAP3133619.1"
                     /translation="MSVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHL
                     VSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKH
                     ERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
                     LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLL
                     AIPMYCLFEIGVFFSRFYVGKGRNREEENDAEAESEKTEE"
     gene            complement(12333..12848)
                     /gene="tatB"
                     /locus_tag="IT892_000370"
     CDS             complement(12333..12848)
                     /gene="tatB"
                     /locus_tag="IT892_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatB"
                     /protein_id="HAP3133620.1"
                     /translation="MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLAT
                     TVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPE
                     KASDEAHTIHNPVVKDNEAAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKT
                     AAPSPSSSDKP"
     gene            complement(12852..13121)
                     /gene="tatA"
                     /locus_tag="IT892_000371"
     CDS             complement(12852..13121)
                     /gene="tatA"
                     /locus_tag="IT892_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HAP3133621.1"
                     /translation="MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMS
                     DDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV"
     gene            complement(13200..14840)
                     /gene="ubiB"
                     /locus_tag="IT892_000372"
     CDS             complement(13200..14840)
                     /gene="ubiB"
                     /locus_tag="IT892_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HAP3133622.1"
                     /translation="MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWM
                     PNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDG
                     KLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
                     PVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRR
                     NFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFF
                     TQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFN
                     RDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTAR
                     RFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAF
                     KEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGAT
                     LVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR"
     gene            complement(14837..15442)
                     /gene="ubiJ"
                     /locus_tag="IT892_000373"
     CDS             complement(14837..15442)
                     /gene="ubiJ"
                     /locus_tag="IT892_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein UbiJ"
                     /protein_id="HAP3133623.1"
                     /translation="MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGF
                     STSLILVFSERQVDVLGEWAGDADCTVIAYASVLPKLRDRQQLTALIRSGELEVQGDI
                     QVVQNFVALADLAEFDPAELLAPYTGDIAAEGISKAMRGGAKFLHHGIKRQQRYVAEA
                     ITEEWRMAPGPLEVAWFAEETAAVERAVDALTKRLEKLEAK"
     gene            complement(15456..16211)
                     /gene="ubiE"
                     /locus_tag="IT892_000374"
     CDS             complement(15456..16211)
                     /gene="ubiE"
                     /locus_tag="IT892_000374"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HAP3133624.1"
                     /translation="MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMS
                     FGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLK
                     MGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVL
                     KPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQ
                     DTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF"
     gene            complement(16306..17733)
                     /gene="rmuC"
                     /locus_tag="IT892_000375"
     CDS             complement(16306..17733)
                     /gene="rmuC"
                     /locus_tag="IT892_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HAP3133625.1"
                     /translation="MDFSIMVYAVIALVGVAIGWLFASYQHAQQKAEQLAEREEMVAE
                     LSAAKQQITQSEHWRAECELLNNEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIR
                     QMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLSPLREQLDGFRRQVQDSF
                     GKEAQERHTLTHEIRNLQQLNAQMAQEAINLTRALKGDNKTQGNWGEVVLTRVLEASG
                     LREGYEYETQVSIENDARSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTR
                     ESALQEHIASVRNHIRLLGRKDYQQLPGLRTLDYVLMFIPVEPAFLLALDRQPELITE
                     ALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQQIADRASKLYDKMRLFIDDMSAI
                     GQSLDKAQDNYRQAMKKLSSGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVSQDEEY
                     RLRSVPEQPNDEAYQRDDEYNQQSR"
     gene            complement(17874..18635)
                     /gene="udp"
                     /locus_tag="IT892_000376"
     CDS             complement(17874..18635)
                     /gene="udp"
                     /locus_tag="IT892_000376"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HAP3133626.1"
                     /translation="MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKL
                     ASHREFTIWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHI
                     NVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSD
                     TFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAG
                     VIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL"
     gene            18897..19712
                     /locus_tag="IT892_000377"
     CDS             18897..19712
                     /locus_tag="IT892_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HAP3133627.1"
                     /translation="MATTQQSGFAPAASPLASTIVQTPDDAIVAGFTSIPSQGDNMPA
                     YHARPKQSDGPLPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFA
                     DIPTLLSGLVAKVPDSQVLADLDHVASWASRNGGDVHRLMITGFCWGGRITWLYAAHN
                     PQLKAAVAWYGKLTGDKSLNSPKQPVDIATDLNAPILGLYGGQDNSIPQESVETMRQA
                     LRAANAKAEIIVYPDAGHAFNADYRPSYHAASAEDGWQRMLEWFKQYGGKKSL"
     gene            complement(19752..22013)
                     /gene="metE"
                     /locus_tag="IT892_000378"
     CDS             complement(19752..22013)
                     /gene="metE"
                     /locus_tag="IT892_000378"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAP3133628.1"
                     /translation="MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELR
                     ARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRG
                     RAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPV
                     LLGPVTWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELP
                     QAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAEL
                     HKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSV
                     ETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAV
                     EKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKG
                     NLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGW
                     VQSYGSRCVKPPIVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPRE
                     DVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEA
                     FRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDY
                     PNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAAL
                     ANMVQAAQNLRRG"
     gene            22250..23203
                     /gene="metR"
                     /locus_tag="IT892_000379"
     CDS             22250..23203
                     /gene="metR"
                     /locus_tag="IT892_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MetR"
                     /protein_id="HAP3133629.1"
                     /translation="MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRL
                     GFRLFVRKSQPLRFTPQGEILLQLANQVLPQISQALQACNEPQQTRLRIAIECHSCIQ
                     WLTPALENFHKNWPQVEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
                     YEVRLVLAPDHPLAAKTRITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSLKSV
                     DNTLLLIQMVAARMGIAALPHWVVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQP
                     VTEAFIRSARNHACDHLPFVKSAERPTYDAPTVRPGSPARL"
     gene            complement(23091..23990)
                     /gene="bioP"
                     /locus_tag="IT892_000380"
     CDS             complement(23091..23990)
                     /gene="bioP"
                     /locus_tag="IT892_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter"
                     /protein_id="HAP3133630.1"
                     /translation="MALLIITTILWAFSFSFYGEYLAGHVDSYFAVLVRVGLAALVFL
                     PFLRTRGNSLKTVGLYMLVGAMQLGVMYMLSFRAYLYLTVSELLLFTVLTPLYITLIY
                     DIMSKRRLRWGYAFSALLAVIGAGIIRYDQVTDHFWTGLLLVQLSNITFAIGMVGYKR
                     LMETRPMPQHNAFAWFYLGAFLVAVIAWFLLGNAQKMPQTTLQWGILVFLGVVASGIG
                     YFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPTFITGALVILASLWVH
                     RKWVAPRSSQTADDRRRDCALSE"
     gene            complement(24066..24866)
                     /gene="yigL"
                     /locus_tag="IT892_000381"
     CDS             complement(24066..24866)
                     /gene="yigL"
                     /locus_tag="IT892_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar/pyridoxal phosphate phosphatase YigL"
                     /protein_id="HAP3133631.1"
                     /translation="MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR
                     HHVDVGQIRDNLEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII
                     TNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPL
                     EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND
                     AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS"
     gene            complement(24874..25896)
                     /gene="pldB"
                     /locus_tag="IT892_000382"
     CDS             complement(24874..25896)
                     /gene="pldB"
                     /locus_tag="IT892_000382"
                     /EC_number="3.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase L2"
                     /protein_id="HAP3133632.1"
                     /translation="MFQQQKDWETRENAFAAFTMGPLTDFWRQRDEAEFTGVDDIPVR
                     FVRFRAQHHDRVVVICPGRIESYVKYAELAYDLFHLGFDVLIIDHRGQGRSGRLLADP
                     HLGHVNRFNDYVDDLAAFWQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIA
                     LTAPMFGIVIRMPSFMARQILNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRY
                     RRNLRFYADDPTIRVGGPTYHWVRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNR
                     MHDRFCELRTAAGHPVEGGRPLVIKGAYHEILFEKDAMRSVALHAIVDFFNRHNSPSG
                     NRSTEV"
     gene            26007..26627
                     /gene="rhtB"
                     /locus_tag="IT892_000383"
     CDS             26007..26627
                     /gene="rhtB"
                     /locus_tag="IT892_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HAP3133633.1"
                     /translation="MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIA
                     GLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSL
                     ASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDII
                     VMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA"
     gene            complement(26689..27309)
                     /gene="rhtC"
                     /locus_tag="IT892_000384"
     CDS             complement(26689..27309)
                     /gene="rhtC"
                     /locus_tag="IT892_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine export protein RhtC"
                     /protein_id="HAP3133634.1"
                     /translation="MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLG
                     ITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEAVSAP
                     APQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVET
                     LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR"
     gene            complement(27373..29202)
                     /gene="recQ"
                     /locus_tag="IT892_000385"
     CDS             complement(27373..29202)
                     /gene="recQ"
                     /locus_tag="IT892_000385"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026263.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAP3133635.1"
                     /translation="MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCL
                     VVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTRE
                     QQLEVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRP
                     EYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLM
                     EKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRA
                     DVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA
                     EAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEG
                     RQEPCGNCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDY
                     GHDKLKVYGMGRDKSHEHWVSVIRQLIHLGLVTQNIAQHSALQLTEAARPVLRGESSL
                     QLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFNDATLIEM
                     AEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE"
     gene            complement(29335..30204)
                     /gene="pldA"
                     /locus_tag="IT892_000386"
     CDS             complement(29335..30204)
                     /gene="pldA"
                     /locus_tag="IT892_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HAP3133636.1"
                     /translation="MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQ
                     EHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGIL
                     GPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGY
                     NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLK
                     IGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQ
                     TRVGVGVMLNDLF"
     gene            30369..30836
                     /locus_tag="IT892_000387"
     CDS             30369..30836
                     /locus_tag="IT892_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HAP3133637.1"
                     /translation="MSAVLTAEQALKLVGEMFVYHMPFNRALGMELERYEKEFAQLAF
                     KNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGSTLTRHETISEDELRQRLSRMGTI
                     DLRVDYLRPGRGERFTATSSLLRAGNKVAVARVELHNEEQLYIASATATYMVG"
     gene            30888..31778
                     /gene="rarD"
                     /locus_tag="IT892_000388"
     CDS             30888..31778
                     /gene="rarD"
                     /locus_tag="IT892_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HAP3133638.1"
                     /translation="MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVI
                     WSFFFMVVLMSICRQWSYLKTLIQTPQKIFMLAVSAVLIGGNWLLFIWAVNNHHMLEA
                     SLGYFINPLVNIVLGMIFLGERFRRMQWLAVILAICGVLVQLWTFGSLPIIALGLAFS
                     FAFYGLVRKKIAVEAQTGMLIETMWLLPVAAIYLFAIADSSTSHMGQNPMSLNLLLIA
                     AGIVTTVPLLCFTAAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEKPGADKMVTFAFI
                     WVALAIFVMDAIYTQRRTSK"
     gene            31837..32253
                     /locus_tag="IT892_000389"
     CDS             31837..32253
                     /locus_tag="IT892_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709624.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133639.1"
                     /translation="MLTGDSYKDVKFMLRIFIPTSNGKISRRRYIFSFILINFIFAFL
                     IIFFNDGEAGFLVIVSTIVLHYLVINMNCQRLRDSGFIYIKTYVFGTLAVYIISIITM
                     IAEDFACSGNGSMIFLICYFSTFSMLMLAPTDSSKQ"
     gene            32267..32647
                     /locus_tag="IT892_000390"
     CDS             32267..32647
                     /locus_tag="IT892_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2628 domain-containing protein"
                     /protein_id="HAP3133640.1"
                     /translation="MSKEYMNDGSLSEKWKYRFNFYDQHGFPGFWGATPEYKAAFKAL
                     KVRQRLTIQMNFIAFFCSWIYLFVLGLWKKAIIVLLLGILSLFVGALIGVNILGIAVA
                     AYVAVNTNKWFYEKEVKGLNTWSL"
     gene            complement(32690..33640)
                     /gene="corA"
                     /locus_tag="IT892_000391"
     CDS             complement(32690..33640)
                     /gene="corA"
                     /locus_tag="IT892_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HAP3133641.1"
                     /translation="MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQS
                     ELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPAAIIFMILAGLAPYLYFKRKNWL"
     gene            34010..34774
                     /locus_tag="IT892_000392"
     CDS             34010..34774
                     /locus_tag="IT892_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="HAP3133642.1"
                     /translation="MAHQLLIGKGMITLNLKRIFLALTLLPLFAVAADDCALSDPTLT
                     VQAYTVNPQTERVKMYWQKANGEAWGTLHALLADINSQGQVQMAMNGGIYDESYAPLG
                     LYIENGQQKVALNLASGEGNFFIRPGGVFYVAGDKVGIVRLDAFKTSKEIQFAVQSGP
                     MLMENGVINPRIHPNVASSKIRNGVGINKHGNAVFLLSQQATNFYDFACYAKAKLNVE
                     QLLYLDGTISHMYMKGGAIPWQRYPFVTMISVERKG"
     gene            complement(34921..37083)
                     /gene="uvrD"
                     /locus_tag="IT892_000393"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
     CDS             complement(34921..37083)
                     /gene="uvrD"
                     /locus_tag="IT892_000393"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HAP3133643.1"
                     /translation="MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIA
                     WLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHH
                     MDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
                     SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNIL
                     VDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAET
                     IRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVV
                     NRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDAL
                     SYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKAL
                     AGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIEN
                     LEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLE
                     FPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
                     VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFG
                     EGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLESV"
     gene            complement(37167..37883)
                     /gene="yigB"
                     /locus_tag="IT892_000394"
     CDS             complement(37167..37883)
                     /gene="yigB"
                     /locus_tag="IT892_000394"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase YigB"
                     /protein_id="HAP3133644.1"
                     /translation="MRFYRPLGRISALTFDLDDTLYDNRPVILRTEREALTFVQNYHP
                     ALRSFQNEDLQRLRQAVREAEPEIYHDVTRWRFRSIEQAMLDAGLSAEEASAGAHAAM
                     INFAKWRSRIDVPQQTHDTLKQLAKKWPLVAITNGNAQPELFGLGDYFEFVLRAGPHG
                     RSKPFSDMYFLAAEKLNVPIGEILHVGDDLTTDVGGAIRSGMQACWIRPENGDLMQTW
                     DSRLLPHLEISRLASLTSLI"
     gene            complement(37883..38779)
                     /gene="xerC"
                     /locus_tag="IT892_000395"
     CDS             complement(37883..38779)
                     /gene="xerC"
                     /locus_tag="IT892_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAP3133645.1"
                     /translation="MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENG
                     LQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVS
                     APKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
                     DLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISAR
                     NVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYT
                     HLDFQHLASVYDAAHPRAKRGK"
     gene            complement(38776..39483)
                     /locus_tag="IT892_000396"
     CDS             complement(38776..39483)
                     /locus_tag="IT892_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 domain-containing protein"
                     /protein_id="HAP3133646.1"
                     /translation="MKQPGEELQETLTELDDRAVVDYLIKNPEFFIRNARAVEAIRVP
                     HPVRGTVSLVEWHMARARNHIHVLEENMALLMEQAIANEGLFYRLLYLQRSLTAASSL
                     DDMLMRFHRWARDLGLAGASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQ
                     HYLGPLNGPELLVVLPEAKAVGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLH
                     EIALMLPELLERWIERV"
     gene            complement(39480..40304)
                     /gene="dapF"
                     /locus_tag="IT892_000397"
     CDS             complement(39480..40304)
                     /gene="dapF"
                     /locus_tag="IT892_000397"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAP3133647.1"
                     /translation="MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQ
                     LLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANG
                     RMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
                     VIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACG
                     SGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL"
     gene            complement(40341..40544)
                     /locus_tag="IT892_000398"
     CDS             complement(40341..40544)
                     /locus_tag="IT892_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP3133648.1"
                     /translation="MKNVFKALTVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKPVET
                     QTQSTVPDKNDRATGDGPSQVNY"
     gene            41007..41327
                     /gene="cyaY"
                     /locus_tag="IT892_000399"
     CDS             41007..41327
                     /gene="cyaY"
                     /locus_tag="IT892_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HAP3133649.1"
                     /translation="MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFE
                     NGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGET
                     VSFR"
     gene            complement(41367..43913)
                     /gene="cyaA"
                     /locus_tag="IT892_000400"
     CDS             complement(41367..43913)
                     /gene="cyaA"
                     /locus_tag="IT892_000400"
                     /EC_number="4.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate cyclase"
                     /protein_id="HAP3133650.1"
                     /translation="MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHY
                     HHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMG
                     STSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENR
                     FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTL
                     YAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP
                     NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVC
                     EKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQ
                     SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLT
                     FIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLY
                     IKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF
                     RNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTIL
                     GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVS
                     GQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEG
                     IIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGS
                     SFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQYFS"
     gene            44300..45241
                     /gene="hemC"
                     /locus_tag="IT892_000401"
     CDS             44300..45241
                     /gene="hemC"
                     /locus_tag="IT892_000401"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HAP3133651.1"
                     /translation="MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTR
                     GDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICERE
                     DPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
                     NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAA
                     LNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGER
                     RGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA"
     gene            45238..45978
                     /gene="hemD"
                     /locus_tag="IT892_000402"
     CDS             45238..45978
                     /gene="hemD"
                     /locus_tag="IT892_000402"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HAP3133652.1"
                     /translation="MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGQQLPQLA
                     DQLAALGESDLLFALSQHAVAFAQSQLHQQDRKWPRLPDYFAIGRTTALALHTVSGQK
                     ILYPQDREISEVLLQLPELQNIAGKRALILRGNGGRELIGDTLTARGAEVTFCECYQR
                     CAIHYDGAEEAMRWQAREVTMVVVTSGEMLQQLWSLIPQWYREHWLLHCRLLVVSERL
                     AKLARELGWQDIKVADNADNDALLRALQ"
     gene            46000..47181
                     /gene="hemX"
                     /locus_tag="IT892_000403"
     CDS             46000..47181
                     /gene="hemX"
                     /locus_tag="IT892_000403"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HAP3133653.1"
                     /translation="MTEQEKTSAVVEETREAVDTTSQPVATEKKSKNNTALILSAVAI
                     AIALAAGIGLYGWGKQQAVNQTATSDALANQLTALQKAQESQKAELEGIIKQQAAQLK
                     QANRQQETLAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAA
                     LLKSADASLADMNDPSLITVRRAITDDIASLSAVSQVDYDGIILKLNQLSNQVDNLRL
                     ADNDSDGSPMDSDGEELSSSISEWRINLQKSWQNFMDNFITIRRRDDTAVPLLAPNQD
                     IYLRENIRSRLLVAAQAVPRHQEETYRQALENVSTWVRAYYDTDDATTKAFLDEVDQL
                     SQQNISMDLPETLQSQAMLEKLMQTRVRNLLAQPAAGTTEAKPAPAPQADTPAAAPQG
                     E"
     gene            47184..48380
                     /gene="hemY"
                     /locus_tag="IT892_000404"
     CDS             47184..48380
                     /gene="hemY"
                     /locus_tag="IT892_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX biogenesis protein HemY"
                     /protein_id="HAP3133654.1"
                     /translation="MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGL
                     AIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQ
                     VEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRV
                     RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTGAWSSLLDIIPSMAKAHV
                     GDEEHRAMLEQQAWIGLMDQARADNGSEGLRNWWKNQSRKTRHQVALQVAMAEHLIEC
                     DDHDTAQQIIIDGLKRQYDDRLLLPIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTL
                     GQSLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTL
                     QNNPPQ"
     gene            49059..50714
                     /locus_tag="IT892_000405"
     CDS             49059..50714
                     /locus_tag="IT892_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HAP3133655.1"
                     /translation="MEFSFSPKRLVVAVAAALPLMASAADTPSTATARKGFAGYDHPN
                     QYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVG
                     FNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMY
                     GQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYT
                     EWRDVHVNPEVALSPDRSEYIKQLPFSKDDVHAVRGGEQQAIADITPKYMEDLDQRWM
                     DYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDVFA
                     NLYKTLEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWK
                     GMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQS
                     NRKAEHYFLNGKLAAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLY
                     TDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD"
     gene            complement(50873..52108)
                     /locus_tag="IT892_000406"
     CDS             complement(50873..52108)
                     /locus_tag="IT892_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase AslB"
                     /protein_id="HAP3133656.1"
                     /translation="MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTH
                     MDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLGLAFYRRAVALQAKYGAGRKISN
                     SFQTNGVLLDDEWCAFLAEHHFLVGLSLDGPPEIHNQYRVTKGGRPTHKLVMRALTLL
                     QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETTARDGLKLH
                     APGDIQGELTEWSVRPEEFGEFLVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVC
                     HHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMIDSPQQQAFGEDKFKQ
                     LPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLL
                     AHGRPASDIMHAHLLVVSK"
     gene            complement(52255..52331)
                     /locus_tag="IT892_000407"
     tRNA            complement(52255..52331)
                     /locus_tag="IT892_000407"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52295..52297),aa:Pro,seq:tgg)
     gene            complement(52374..52460)
                     /locus_tag="IT892_000408"
     tRNA            complement(52374..52460)
                     /locus_tag="IT892_000408"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52424..52426),aa:Leu,seq:cag)
     gene            complement(52481..52556)
                     /locus_tag="IT892_000409"
     tRNA            complement(52481..52556)
                     /locus_tag="IT892_000409"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52521..52523),aa:His,seq:gtg)
     gene            complement(52615..52691)
                     /locus_tag="IT892_000410"
     tRNA            complement(52615..52691)
                     /locus_tag="IT892_000410"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(52655..52657),aa:Arg,seq:ccg)
     gene            complement(52794..54179)
                     /locus_tag="IT892_000411"
     CDS             complement(52794..54179)
                     /locus_tag="IT892_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP3133657.1"
                     /translation="MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPS
                     VLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMA
                     VGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
                     IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVEL
                     IGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFA
                     KIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVA
                     GVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAA
                     IASHPFRSILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGL
                     NRHGKAHKLEE"
     gene            complement(54370..55110)
                     /gene="rffM"
                     /locus_tag="IT892_000412"
     CDS             complement(54370..55110)
                     /gene="rffM"
                     /locus_tag="IT892_000412"
                     /EC_number="2.4.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /protein_id="HAP3133658.1"
                     /translation="MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAI
                     NAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMA
                     RAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASG
                     AQIVTVAMGSPKQEIIMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWL
                     YRLLSQPSRIKRQLRLLRYLRWHYTGNL"
     gene            complement(55113..56465)
                     /gene="wzyE"
                     /locus_tag="IT892_000413"
     CDS             complement(55113..56465)
                     /gene="wzyE"
                     /locus_tag="IT892_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen assembly polymerase"
                     /protein_id="HAP3133659.1"
                     /translation="MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFL
                     LTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPR
                     RPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKR
                     FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIG
                     IIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLA
                     LLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAIS
                     PTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIF
                     NMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
                     "
     gene            complement(56462..57541)
                     /gene="rffT"
                     /locus_tag="IT892_000414"
                     /gene_synonym="wecF"
     CDS             complement(56462..57541)
                     /gene="rffT"
                     /locus_tag="IT892_000414"
                     /gene_synonym="wecF"
                     /EC_number="2.4.1.325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDP-N-acetylfucosamine:lipid II
                     N-acetylfucosaminyltransferase"
                     /protein_id="HAP3133660.1"
                     /translation="MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDD
                     GLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPS
                     QFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGEL
                     LFFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVP
                     MGYPPNNEAYIEEVRQAGLELFSEENLQILSEKLEFDAYLALLRQCDLGYFIFARQQG
                     IGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKN
                     TIAFFSPNYLQGWQRALAIAAGEVA"
     gene            complement(57538..58788)
                     /gene="wzxE"
                     /locus_tag="IT892_000415"
     CDS             complement(57538..58788)
                     /gene="wzxE"
                     /locus_tag="IT892_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid III flippase WzxE"
                     /protein_id="HAP3133661.1"
                     /translation="MSLAKASLWTAASTLVKIGAGLLVGKLLAVSFGPAGLGLAANFR
                     QLITVLGVLAGAGIFNGVTKYVAQYHDNPQQLRRVVGTSSAMVLGFSTLMALVFVLAA
                     APISQGLFGNTDYQGLVRLVALVQMGIAWGNLLLALMKGFRDAAGNALSLIVGSLIGV
                     LAYYVSYRLGGYEGALLGLALIPALVVIPAAIMLIKRGVIPLSYLKPSWDNGLAGQLS
                     KFTLMALITSVTLPVAYIMMRKLLAAQYSWDEVGIWQGVSSISDAYLQFITASFSVYL
                     LPTLSRLTEKRDITREVVKSLKFVLPAVAAASFTVWLLRDFAIWLLLSNKFTAMRDLF
                     AWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEVSQFTLLMVFAHWLIPAHGALGAAQ
                     AYMATYIVYFSLCCGVFLLWRRRA"
     gene            complement(58790..59920)
                     /gene="rffA"
                     /locus_tag="IT892_000416"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
     CDS             complement(58790..59920)
                     /gene="rffA"
                     /locus_tag="IT892_000416"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
                     /EC_number="2.6.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="HAP3133662.1"
                     /translation="MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRF
                     GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRP
                     DTMNIDETLIEAAITDKTRVIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMST
                     YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFR
                     GQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGR
                     IELPSIPDGCVQNAHMFYIKLRDIDDRSALINFLKEAEIMAVFHYIPLHGCPAGEHFG
                     EFHGEDRYTTKESERLLRLPLFYNLSPVNQRTVIATLLNYFS"
     gene            complement(59925..60599)
                     /locus_tag="IT892_000417"
     CDS             complement(59925..60599)
                     /locus_tag="IT892_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-fucosamine acetyltransferase"
                     /protein_id="HAP3133663.1"
                     /translation="MPVRASIEPLTWENAFFGVNSAIVRITSEAPLLTPDALAPWSRV
                     QAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASA
                     AFAQSRFRAPWYAPDASSRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNA
                     TDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVEST
                     AYWLYR"
     gene            complement(60577..61458)
                     /gene="rfbA"
                     /locus_tag="IT892_000418"
     CDS             complement(60577..61458)
                     /gene="rfbA"
                     /locus_tag="IT892_000418"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAP3133664.1"
                     /translation="MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLA
                     GIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS
                     CLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK
                     PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRG
                     FAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT
                     GYGQYLLELLRARPRQY"
     gene            complement(61477..62544)
                     /gene="rffG"
                     /locus_tag="IT892_000419"
     CDS             complement(61477..62544)
                     /gene="rffG"
                     /locus_tag="IT892_000419"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAP3133665.1"
                     /translation="MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSL
                     APVAQSERFAFEKVDICDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKSLPVYG
                     NGQQIRDWLYVEDHARALYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPN
                     KPHGVAHYRDLITFVADRPGHDLRYAIDASKIARELGWLPQETFESGMRKTVQWYLAN
                     ESWWKQVQDGSYQGERLGLKG"
     gene            complement(62544..63806)
                     /gene="wecC"
                     /locus_tag="IT892_000420"
     CDS             complement(62544..63806)
                     /gene="wecC"
                     /locus_tag="IT892_000420"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HAP3133666.1"
                     /translation="MSFATISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINR
                     GEIHIVEPDLASVVKTAVEGGFLRASTTPVEADAWLIAVPTPFKGDHEPDMTYVESAA
                     RSIAPVLKKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPER
                     VLPGQVMVELIKNDRVIGGMTPVCSARASELYKIFLEGECVVTNSRTAEMCKLTENSF
                     RDVNIAFANELSLICADQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVA
                     QNPQQARLIRTAREVNDHKPFWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNI
                     DDLRESPAMEIAELIAQWHSGETLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVM
                     LVDHSQFKVINGDNVHQQYVVDAKGVWR"
     gene            complement(63803..64933)
                     /gene="wecB"
                     /locus_tag="IT892_000421"
     CDS             complement(63803..64933)
                     /gene="wecB"
                     /locus_tag="IT892_000421"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HAP3133667.1"
                     /translation="MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLD
                     QVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLAT
                     SLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLREN
                     VADSRIFITGNTVIDALLWVRDQVMSSDKLRSELAANYPFIDPDKKMILVTGHRRESF
                     GRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPF
                     VWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVE
                     EVTRLLKDENEYQAMSRAHNPYGDGQACSRILEALKNNRISL"
     gene            complement(64989..66035)
                     /gene="wzzE"
                     /locus_tag="IT892_000422"
     CDS             complement(64989..66035)
                     /gene="wzzE"
                     /locus_tag="IT892_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA polysaccharide chain length modulation
                     protein"
                     /protein_id="HAP3133668.1"
                     /translation="MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIA
                     LAYTFFARQEWSSTAITDRPTVNMLGGYYSQQQFLRNLDVRSNMASADQPSVMDEAYK
                     EFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDS
                     VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKA
                     IYDRRMNSIEQALKIAEQHNISRSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGP
                     AFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGG
                     LIGAGVALTRRCSK"
     gene            complement(66047..67150)
                     /gene="wecA"
                     /locus_tag="IT892_000423"
     CDS             complement(66047..67150)
                     /gene="wecA"
                     /locus_tag="IT892_000423"
                     /EC_number="2.7.8.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /protein_id="HAP3133669.1"
                     /translation="MNLLAVSTDLISIFLFTTLFLFFARKVAKKVGLVDKPNFRKRHQ
                     GLIPLVGGISVYAGICFTFGIVDYYIPHASLYLACAGVLVFIGALDDRFDISVKIRAT
                     IQAAVGIVMMVFGKLYLSSLGYIFGSWEMVLGPFGYFLTLFAVWAAINAFNMVDGIDG
                     LLGGLSCVSFAAIGMILWFDGQTSLAIWCFAMIAAILPYIMLNLGILGRRYKVFMGDA
                     GSTLIGFTVIWILLETTQGKTHPISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPD
                     RQHIHHLIMRAGFTSRQAFVLITLAAALLASIGVLAEYSHFVPEWVMLVLFLLAFFLY
                     GYCIKRAWKVARFIKRVKRRLRRNRGGSPNLTK"
     gene            complement(67390..68649)
                     /gene="rho"
                     /locus_tag="IT892_000424"
     CDS             complement(67390..68649)
                     /gene="rho"
                     /locus_tag="IT892_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAP3133670.1"
                     /translation="MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAK
                     SGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIR
                     PPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
                     VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTE
                     MQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNT
                     VVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEE
                     FKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGE
                     IDAMEFLINKLAMTKTNDDFFEMMKRS"
     gene            complement(68734..68835)
                     /gene="rhoL"
                     /locus_tag="IT892_000425"
     CDS             complement(68734..68835)
                     /gene="rhoL"
                     /locus_tag="IT892_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rho operon leader peptide rhoL"
                     /protein_id="HAP3133671.1"
                     /translation="MRSEQISGSSLNPSCRFSSAYSPVTRQRKDMSR"
     gene            complement(68976..69305)
                     /gene="trxA"
                     /locus_tag="IT892_000426"
     CDS             complement(68976..69305)
                     /gene="trxA"
                     /locus_tag="IT892_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HAP3133672.1"
                     /translation="MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILD
                     EIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
                     FLDANLA"
     gene            69436..70701
                     /gene="rhlB"
                     /locus_tag="IT892_000427"
     CDS             69436..70701
                     /gene="rhlB"
                     /locus_tag="IT892_000427"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlB"
                     /protein_id="HAP3133673.1"
                     /translation="MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTL
                     AGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHA
                     DAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
                     VVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEY
                     IEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHL
                     AADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLP
                     DDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTD
                     LPKPLRLTRPRTGNGPRRTGAPRNRRRSG"
     gene            70837..72321
                     /gene="gppA"
                     /locus_tag="IT892_000428"
     CDS             70837..72321
                     /gene="gppA"
                     /locus_tag="IT892_000428"
                     /EC_number="3.6.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-5'-triphosphate,3'-diphosphate
                     diphosphatase"
                     /protein_id="HAP3133674.1"
                     /translation="MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAA
                     GLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQE
                     ILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSL
                     SMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQAL
                     QEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIF
                     TELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVA
                     ANFFDQVENEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPA
                     QKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMT
                     LQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWPLEVH"
     gene            complement(72368..74389)
                     /gene="rep"
                     /locus_tag="IT892_000429"
     CDS             complement(72368..74389)
                     /gene="rep"
                     /locus_tag="IT892_000429"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HAP3133675.1"
                     /translation="MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMK
                     ANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGER
                     DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQD
                     TNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQN
                     YRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGELIAH
                     HFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV
                     LTNPDDDSAFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGY
                     EALTRFTHWLAEIQRLAEREPIAAVRDLIHGMDYESWLYETSPSPKAAEMRMKNVNQL
                     FSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFP
                     YVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRP
                     EPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRGK"
     gene            74606..75054
                     /locus_tag="IT892_000430"
                     /pseudo
     CDS             74606..75054
                     /locus_tag="IT892_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            75253..75534
                     /gene="ppiC"
                     /locus_tag="IT892_000431"
     CDS             75253..75534
                     /gene="ppiC"
                     /locus_tag="IT892_000431"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004097481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PpiC"
                     /protein_id="HAP3133676.1"
                     /translation="MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSG
                     KRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN"
     gene            complement(75621..77096)
                     /gene="ilvC"
                     /locus_tag="IT892_000432"
     CDS             complement(75621..77096)
                     /gene="ilvC"
                     /locus_tag="IT892_000432"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HAP3133677.1"
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVG
                     CGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLV
                     INLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
                     VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDL
                     MGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDR
                     LSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREET
                     GKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLH
                     ELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPE
                     GAVDNGQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG"
     gene            77246..78139
                     /gene="ilvY"
                     /locus_tag="IT892_000433"
     CDS             77246..78139
                     /gene="ilvY"
                     /locus_tag="IT892_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator IlvY"
                     /protein_id="HAP3133678.1"
                     /translation="MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLG
                     QPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTIDQQGPSLSGELHIFCSVTAA
                     YSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSM
                     LENLAVVLIAPALPCPVRNQVSVEKPDWSTVPFIMADQGPVRRRIELWFRRNKISNPM
                     IYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCA
                     QKKRLHEPLIEAFWKILPNHK"
     gene            complement(78191..79735)
                     /gene="ilvA"
                     /locus_tag="IT892_000434"
     CDS             complement(78191..79735)
                     /gene="ilvA"
                     /locus_tag="IT892_000434"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HAP3133679.1"
                     /translation="MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRL
                     DNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLG
                     VKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHP
                     MVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSA
                     CLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKD
                     LFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSGANVNFHGLRYVSERCELG
                     EQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEER
                     KEILQMLNDGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRF
                     LNTLGTYWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLNELGYDCHDETNNPAF
                     RFFLAG"
     gene            complement(79738..81588)
                     /gene="ilvD"
                     /locus_tag="IT892_000435"
     CDS             complement(79738..81588)
                     /gene="ilvD"
                     /locus_tag="IT892_000435"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HAP3133680.1"
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFT
                     QFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
                     KLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGN
                     GSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMG
                     GSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIG
                     ILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFS
                     QDCRWDTLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTG
                     PAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKAC
                     ALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELA
                     ARREAQDARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG"
     gene            complement(81653..82582)
                     /gene="ilvE"
                     /locus_tag="IT892_000436"
     CDS             complement(81653..82582)
                     /gene="ilvE"
                     /locus_tag="IT892_000436"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HAP3133681.1"
                     /translation="MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYD
                     SHKGPVVFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLIF
                     VGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAK
                     AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSAL
                     PGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEG
                     RCGPVTKRIQQAFFGLFTGETEDKWGWLDQVNQ"
     gene            complement(82602..82865)
                     /gene="ilvM"
                     /locus_tag="IT892_000437"
     CDS             complement(82602..82865)
                     /gene="ilvM"
                     /locus_tag="IT892_000437"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 small subunit"
                     /protein_id="HAP3133682.1"
                     /translation="MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQN
                     INIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRA"
     gene            complement(82862..84508)
                     /locus_tag="IT892_000438"
     CDS             complement(82862..84508)
                     /locus_tag="IT892_000438"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 catalytic subunit"
                     /protein_id="HAP3133683.1"
                     /translation="MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGVEHLLC
                     RHEQGAAMAAIGYARATGKTGVCIATSGPGATNLITGLADALLDSIPVVAITGQVSAP
                     FIGTDAFQEVDVLGLSLACTKHSFLVQSLEELPRIMAEAFDVACSGRPGPVLVDIPKD
                     IQLASGDLEPWFTTVENEVTFPHAEVEQARQMLAKAQKPMLYVGGGVGMAQAVPALRE
                     FLAATKMPATCTLKGLGAVEADYPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDR
                     VTGKLNTFAPHASVIHMDIDPAEMNKLRQAHVALQGDLNALLPALQQPLNINDWQQHC
                     AQLRDEHSWRYDHPGDAIYAPLLLKQLSDRKPADCVVTTDVGQHQMWAAQHIAHTRPE
                     NFITSSGLGTMGFGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTVKRKQLPLKI
                     VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLMLASAFGIHGQHITRKDQVEAAL
                     DTMLNSDGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS"
     gene            complement(84511..84561)
                     /locus_tag="IT892_000439"
     CDS             complement(84511..84561)
                     /locus_tag="IT892_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133684.1"
                     /translation="MNNSTKFCFSRFRTGN"
     gene            complement(84648..84746)
                     /gene="ilvL"
                     /locus_tag="IT892_000440"
     CDS             complement(84648..84746)
                     /gene="ilvL"
                     /locus_tag="IT892_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilv operon leader peptide"
                     /protein_id="HAP3133685.1"
                     /translation="MTALLRVISLVVISVVVIIIPPCGAALGRGKA"
     gene            85099..86619
                     /locus_tag="IT892_000441"
     CDS             85099..86619
                     /locus_tag="IT892_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418214.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HAP3133686.1"
                     /translation="MSLSIVHTRAALGVNAPPITVEVHISKGLPGLTMVGLPETTVKE
                     ARDRVRSAIINSGYEYPAKKITINLAPADLPKEGGRYDLPIAIALLAASEQLTANKLD
                     EYELVGELALTGALRGVPGAISSATEAIKSGRKIIVAKDNEDEVGLINGEGCLIADHL
                     QAVCAFLEGKHALERPKPTDAVSRALQHDLSDVIGQEQGKRGLEITAAGGHNILLIGP
                     PGTGKTMLASRINGLLPDLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSASLT
                     AMVGGGAIPGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITY
                     PARFQLVAAMNPSPTGHYQGNHNRCTPEQTLRYLNRLSGPFLDRFDLSLEIPLPPPGI
                     LSKTVVPGESSATVKQRVMAARERQFKRQNKLNAWLDSPEIRQFCKLESEDAMWLEGT
                     LIHLGLSIRAWQRLLKVARTIADIDQSDIITRQHLQEAVSYRAIDRLLIHLQKLLT"
     gene            complement(86644..86982)
                     /gene="maoP"
                     /locus_tag="IT892_000442"
     CDS             complement(86644..86982)
                     /gene="maoP"
                     /locus_tag="IT892_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ori organization protein MaoP"
                     /protein_id="HAP3133687.1"
                     /translation="MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGYAFNE
                     LDLGKREPVTEEEKLFVAVCRGEREPVTEAERVWSKYMTRIKRPKRFHTLSGGKPQVE
                     GAEDYTDSDD"
     gene            87101..87940
                     /gene="hdfR"
                     /locus_tag="IT892_000443"
     CDS             87101..87940
                     /gene="hdfR"
                     /locus_tag="IT892_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator HdfR"
                     /protein_id="HAP3133688.1"
                     /translation="MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLG
                     VNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWEC
                     MLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
                     LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQ
                     IAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLD
                     EVY"
     gene            complement(88036..88111)
                     /locus_tag="IT892_000444"
     tRNA            complement(88036..88111)
                     /locus_tag="IT892_000444"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(88076..88078),aa:Trp,seq:cca)
BASE COUNT        21400 a        23947 c        22415 g        20356 t
ORIGIN      
        1 ttctttatgc ttatttcagc gtcggtttgt cggttaaatg ggcgatttct cgggcgaaat
       61 tcgccacctg ctcccaatcg gtatagacaa cttctttgcg cgtatccgtt tcaccgcctg
      121 acatcttcat aatcagcttg atcataaaac ggtcgtacca gcgataacgt gggtaacgca
      181 gcgccccggc aatgaccgcg cagcgatcgg gacgccattg cgagttcatc agaaacttgc
      241 gcgcgtagct gttggtctgt ggagtacgct tctccggttt gcgcgccacc agattcacgg
      301 agtaaaaggc gctcggcatc gaattcagcc gcgtcgcatg ttttttgaca aattcctgga
      361 acgctgaatg gtagtgacca tagcgaatag aagcaccaat gaccacacgg tcatagtttt
      421 cccactgtgg ttcttcaatg cggtgcacat tggcgacatc cgcctggatc cccagttctt
      481 tcagttccga agccaggtag gaggcaatct cgcgcgtttg tccgtccctt gttgagaaaa
      541 gaattaatgt tttcacgtat tactccatca ttcacgccag aaagtcgggg taaagagcac
      601 cagcaatgta aagacctcga gacgaccaaa cagcatgttg gcaatcagga tccatttagc
      661 caccgggttc atactggtaa agttatcagc aaccacgcca agccctggcc ccaggttatt
      721 caatgtcgca acaaccgacg caaaggcaga aaagtcatcc acgcccgtgg cgataatcgc
      781 cagcatactg acaataaaca ccaatgcata ggcggagaaa aatccccaaa cggcttcgag
      841 gatacgttcc ggcagtgcgc gattccccag cttaatgcta tagacggcgt tcggatgcac
      901 cagtcgtttc agctcacggt tcccctgctt aaacagcagc aggatgcgga tcaccttcag
      961 gccaccgccc gttgacccgg cgcaaccgcc gataaaggct gaacataaaa gcagtaccgg
     1021 caaaaagagc ggccagcggg caatgctgtc agttgtaaac ccggcggttg tcgccatcga
     1081 caccacctgg aaaaacgcct ggttaattgt catcagcgcc gaactgtaga cattatgaaa
     1141 ccacagtacg agggtacaaa taaccaccag cgtaaactgt acgccgataa acatgcgaaa
     1201 ttccggatcg cgccaataaa ccttcagact acgcccactt aacagtgaaa agtgcagacc
     1261 gtagttacag ccggagatca gcaggaagat agcaatgata gtgttaatag tcgggctatc
     1321 gaaataaccg atactggcat catgtgtcga gaagccgcca atagcgatag tcgcaaagct
     1381 atggccgatg gcatcaaagg catccattcc ggcaaaccac aacgccagcg cacaggcgac
     1441 ggtcagcaag acataaatca accacagggt tttcgccgtt tccgcaattc gcgggcgcat
     1501 tttgttatct ttcagcgggc cgggcatttc tgcgcgatag agctgcatcc cacccacgcc
     1561 gaggataggc agtatcgcaa ccgccaacac gatgatcccc atcccgccaa accattgcag
     1621 catctggcga taaaagagga tggcgtgagg gagcgaatcc agccccacca gcgtagtggc
     1681 tcccgtagtg gtcaggccag agaaagattc aaaaaacgca tcggtaatcg tgaggttcgg
     1741 gctttccgag aagataaaag ggagcgcacc gacgctaccc agcacggtcc agaacagcac
     1801 cactatcaga aacccctcac gggatttaag ttcgcctttc tctttgcggt tcggccacca
     1861 cagcatagag ccaatggcga gggcgacaaa aaaggtctgg gtaaaagcgc ggcccgctcc
     1921 atcccggtag atgagtgcta ccagcccagg gataatcatg gtccctgaaa ataagatgac
     1981 cagtagtcca acgattcggg taatggcgcg aaaatgcatc tctgccgctt ccttagttct
     2041 gcaaaacgaa gtggggatta ttcttcaatc gctaacaatt gcaatgaacc acggctaaaa
     2101 tccgccagct ttgcggaaaa ttcagccact ttcgccgccg gaagcgccac ccgcagcaga
     2161 acgaatgcct gataatcact gttgataatt ttgccgtcac actgccccag caacgcttca
     2221 atgccggtta actgatgata ttcacattgc aaagtatatt cggttaatgg cgtcttgcgt
     2281 tgggtcgtta gctggcgcag cgcctgattc acgccgccgc catacgcttt cactaaccca
     2341 ccggtgccaa gcaatatgcc gccgtagtag cgcactacca cagcggtaat ttccccgacg
     2401 ccgctgccca ttagctgggc gagcatcggt ttacctgccg ttcccgccgg ctccccgtcg
     2461 tcagagaaac ccagctgttg agaatcatcc ggcgcacccg cgacccacgc cacgcaatgg
     2521 tgccgggcat cggggtgttc tgcccgcacc gattcaacaa acgctttcgc cgcctcaacg
     2581 ccatcggtat gcgccaacat cgttatgaag cggctctttt tgatctcttc aacgaccgtg
     2641 accggtgccg caggaattaa ccagctttcc atcacgccag tttcagatcc cgggtcatgt
     2701 tttccacgtt gttttcgtgg atcaccacgt tgtcttcgat acgaatgccg ccgaacggtt
     2761 tcagtgcttc aattttctgc cagttgaagt gcttgctgaa ctgcccttca cgccacggtg
     2821 ccagtagcga ttcgatgaag tagatacccg gttcgatggt taacaccatg cccggctgga
     2881 gaatacgggt gcagcgcagg tacggatatt ttgccggtgc cgcgaggtgc gtaccgctat
     2941 catcctgcat aaaaccagcg acgtcatgca cctgcaggcc cagcggatgg ccgataccat
     3001 gcggcataaa cggcccggta agatcgtttt cgaccatcgc ttcttcactc atatcggtga
     3061 tgatttgatg tttacgcagc agtttggcga tgcgctgatg gaactggatg tggtaatcca
     3121 catagctgac gcctgctttc atggtggcga tcagcgccag ttgttcatca ttaacgtcct
     3181 tcaccagctg cgcgtagtcg ttgtcacttt ttgccgacca ggtacgggtc aggtcagccg
     3241 catagccgtt atattctgcc ccggcatcca gcaggaagct gcgcatctct tccggtgcct
     3301 gatggtccag tttggtgtaa tgcagtaccg cagcgtgttc gttaagcgcc acaatgttgc
     3361 tgtaaggtac gtcggtatca cgatgaccgg tcgcggtcag ataggcaatg ttgatatcga
     3421 actcgctcat gccagaacgg aacgcttctt ctgccgcgcg gtgaccgttg accgccattt
     3481 tctgcgcttc acgcatacag gccagttcgt actcagtttt gaaggagcga tagtaatgca
     3541 ggtagtcgat aacccctttc gggttgatgt tgctggcctc aatacccagt tgcagcgcac
     3601 gttccggcac cggaccgata taaccgatat tgccgcgcgc agcaggcagc aggctaccaa
     3661 tgccatcggc tttcggcagc gcgatcactt ccacatcttc agtccagaaa gaggtcggca
     3721 gcggttcgac gttgtgccag taatcaaccg gcagatagaa ccacagtttc ggcttgttca
     3781 cgccatccac cagcaaccag cagtttggca cctgagttac cggcacccac gctttgaatt
     3841 gcgggttcac tttaaacgga tagggatgat cgtcgagaaa aacattgaac agctcgccgg
     3901 agtgaataag taacgcatcc agcttgaagc gcgccagcgc atcgcgagtc cgttcttgta
     3961 aggtagctat atgattttta tagagcgagg ccagtgattc cattttttac ccttctgttt
     4021 ttttgacctt aagtctccgc atcttagcac atcgttcatc cagagcgtga tttctgccga
     4081 gcgtgatcag atcggcattt ctttaatctt ttgtttgcat atttttaaca caaaatacac
     4141 acttcgactc atctggtacg accagatcac cttgcggatt caggagactg acatgcttta
     4201 caaaggcgac accctgtacc ttgactggct ggaagatggc attgccgaac tggtatttga
     4261 tgccccaggt tcagttaata aactcgacac tgcgaccgtc gccagcctcg gcgaggccat
     4321 cggcgtgctg gaacagcaat cagatctaaa agggctgctg ctgcgttcga acaaagcagc
     4381 ctttatcgtc ggtgctgata tcaccgaatt tttgtccctg ttcctcgttc ctgaagaaca
     4441 gttaagtcag tggctgcact ttgccaatag cgtgtttaat cgcctggaag atctgccggt
     4501 gccgaccatt gctgccgtca atggctatgc gctgggcggt ggctgcgaat gcgtgctggc
     4561 gaccgattat cgtctggcga cgccggatct gcgcatcggt ctgccggaaa ccaaactggg
     4621 catcatgcct ggctttggcg gttctgtacg tatgccacgt atgctgggcg ctgacagtgc
     4681 gctggaaatc attgccgccg gtaaagatgt cggcgcggat caggcgctga aaatcggtct
     4741 ggtggatggc gtagtcaaag cagaaaaact ggttgaaggc gcaaaggcgg ttttacgcca
     4801 ggccattaac ggcgacctcg actggaaagc aaaacgtcag ccgaagctgg aaccactaaa
     4861 actgagcaag attgaagcca ccatgagctt caccatcgct aaagggatgg tcgcacaaac
     4921 agcggggaaa cattatccgg cccccatcac cgcagtaaaa accattgaag ctgcggcccg
     4981 ttttggtcgt gaagaagcct taaacctgga aaacaaaagt tttgtcccgc tggcgcatac
     5041 caacgaagcc cgcgcactgg tcggcatttt ccttaacgat caatatgtaa aaggcaaagc
     5101 gaagaaactc accaaagacg ttgaaacccc gaaacaggcc gcggtgctgg gtgcaggcat
     5161 tatgggcggc ggcatcgctt accagtctgc gtggaaaggc gtgccggttg tcatgaaaga
     5221 tatcaacgac aagtcgttaa ccctcggcat gaccgaagcc gcgaaactgc tgaacaagca
     5281 gcttgagcgc ggcaagatcg atggtctgaa actggctggc gtgatctcca caatccaccc
     5341 aacgctcgac tacgccggat ttgaccgcgt ggatattgtg gtagaagcgg ttgttgaaaa
     5401 cccgaaagtg aaaaaagccg tactggcaga aaccgaacaa aaagtacgcc aggataccgt
     5461 gctggcgtct aacacttcaa ccattcctat cagcgaactg gccaacgcgc tggaacgccc
     5521 ggaaaacttc tgcgggatgc acttctttaa cccggtccac cgaatgccgt tggtagaaat
     5581 tattcgcggc gagaaaagct ccgacgaaac catcgcgaaa gttgtcgcct gggcgagcaa
     5641 gatgggcaag acgccgattg tggttaacga ctgccccggc ttctttgtta accgcgtgct
     5701 gttcccgtat ttcgccggtt tcagccagct gctgcgcgac ggcgcggatt tccgcaagat
     5761 cgacaaagtg atggaaaaac agtttggctg gccgatgggc ccggcatatc tgctggacgt
     5821 tgtgggcatt gataccgcgc atcacgctca ggctgtcatg gcagcaggct tcccgcagcg
     5881 gatgcagaaa gattaccgcg atgccatcga cgcgctgttt gatgccaacc gctttggtca
     5941 gaagaacggc ctcggtttct ggcgttataa agaagacagc aaaggtaagc cgaagaaaga
     6001 agaagacgcc gccgttgaag acctgctggc agaagtgagc cagccgaagc gcgatttcag
     6061 cgaagaagag attatcgccc gcatgatgat cccgatggtc aacgaagtgg tgcgctgtct
     6121 ggaggaaggc attatcgcca ctccggcgga agcggatatg gcgctggtct acggcctggg
     6181 cttccctccg ttccacggcg gcgcgttccg ctggctggac accctcggta gcgcaaaata
     6241 cctcgatatg gcacagcaat atcagcacct cggcccgctg tatgaagtgc cggaaggtct
     6301 gcgtaataaa gcgcgtcata acgaaccgta ctatcctccg gttgagccag cccgtccggt
     6361 tggcgacctg aaaacggctt aaggagtcac aatggaacag gttgtcattg tcgatgcaat
     6421 tcgcaccccg atgggccgtt cgaagggcgg tgcttttcgt aacgtgcgtg cagaagatct
     6481 ctccgctcat ttaatgcgta gcctgctggc gcgtaacccg gcgctggaag cggcggccct
     6541 cgacgatatt tactggggtt gtgtgcagca gacgctggag cagggtttta atatcgcccg
     6601 taacgcggcg ctgctggcag aagtaccaca ctctgtcccg gcggttaccg ttaatcgctt
     6661 gtgtggttca tccatgcagg cactgcatga cgcagcacga atgatcatga ctggcgatgc
     6721 gcaggcatgt ctggttggcg gcgtggagca tatgggccat gtgccgatga gtcacggcgt
     6781 cgattttcac cccggcctga gccgcaatgt tgccaaagcg gcgggcatga tgggcttaac
     6841 ggcagaaatg ctggcgcgta tgcacggtat cagccgtgaa atgcaggatg cctttgccgc
     6901 gcggtcacac gcccgcgcct gggccgccac gcagtcggcc gcatttaaaa atgaaatcat
     6961 cccgaccggt ggtcacgatg ccgacggcgt cctgaagcag tttaattacg acgaagtgat
     7021 tcgcccggaa accaccgtgg aagccctcgc cacgctgcgt ccggcgtttg atccagtaaa
     7081 cggtatggta acggcgggca catcttctgc actttccgat ggcgcagctg ccatgctggt
     7141 gatgagtgaa agccgcgccc atgaattagg tcttaagccg cgcgctcgtg tgcgttcgat
     7201 ggcggtcgtt ggttgtgacc catcgattat gggttacggc ccggttccgg cctcgaaact
     7261 ggcgctgaaa aaagcggggc tttctgccag cgatatcggc gtgtttgaaa tgaacgaagc
     7321 ctttgccgcg cagatcctgc catgtattaa agatctggga ctaattgagc agattgacga
     7381 gaagatcaac ctcaacggtg gcgcgatcgc gctgggtcat ccgctgggtt gttccggtgc
     7441 gcgtatcagc accacgctgc tgaatctgat ggaacgcaaa gacgttcagt ttggtctggc
     7501 gacgatgtgt atcggtctgg gtcagggtat tgcgacggtg tttgagcggg tttaaccact
     7561 tgccggatgc ggcgtgaacg ccttatccgg tctaccgatc cggcaccaat gtaggcctga
     7621 taagacgcgc cagcgtcgca tcaggcatca tgcaccaatt gccggatgcg gcgtaaacgc
     7681 cttatccggc ctacggttcg gactatttgt aggcacgata agacgcgaca gcgtcgcatc
     7741 gggcatggtt tgccagatac gtcatagatc taaatgccac tgaataacag tttagttgcc
     7801 gttcttcccg cctgtcaggg gcgggttttt ttatatctca gataaatgca aacgcatcgc
     7861 caaacaggcg atcttcccgc gcattacgct cactgcaaaa cagatcgcgg gcaattttcg
     7921 ccatctcaaa acgtccggca atatagatat catgctctgc cagcgtaccg tgatcctgca
     7981 ataccgccgt taacacggtg ccagtacgcc cacgccagcc cgcttccggt tgttcaacca
     8041 ccggcaccac ttgcagacca ggatgcttca acgaaagcgc ctcaagctcg cagagatcat
     8101 acagatgctg ctcttcacgc ccgccccagt aaatggtgat atcacggttt gggttacgcg
     8161 ccaacgctgt cagcaaaatc gagcgggcat aagagaaccc ggtgccgccc gcaatcaaaa
     8221 tcatcggacg ctcttcatca tcgcgcagcc acgcttctcc gtggggaatg tcgaccacga
     8281 tttgatgatc tttgaggatg cggtccatga ctgctttcgc gtaaaggttg atttcagaag
     8341 cgccaatatg cagctcgata aacccttttt catccggcgt cgaagccatt gagaacggac
     8401 gtttgtcgcg ctcatccatc actaccatca aatactgacc agcacgaaaa gaaaaggccg
     8461 cgtctggcac gatgcggaca cgatatacgg tatccgtgat agcttctacc gaggtcactt
     8521 tacagcttaa ggttgtcatg cgctttctct gtcggatcga taaatagggc aaaacaaacg
     8581 cgcatcaggc gcttttaccg ttgttaaaaa tagccagttc atcccagatg gcgtcaatat
     8641 gcgcgacaac atctggatct tttttgatgg gacgtcccca ttcacgctgg gtttcccccg
     8701 gccatttatt cgtggcatcc agccccattt ttgaacccag cccggagaca ggcgaggcaa
     8761 aatccagata atcaataggc gtattttcta ccagaacagt atcccgcgcc gggtccatac
     8821 gggtggtaat cgcccaaatc acatcgttcc agtcgcgtgc gttaacgtca tcatcgcaaa
     8881 cgatcacaaa tttagtgtac ataaactggc gtaagaacga ccagacgccc atcatgacgc
     8941 gcttcgcgtg tccggcgtac tgttttttga ttgtcactac cgccaggcga taagagcagc
     9001 cttccggcgg caggtaaaaa tcgacaattt ccgggaactg tttttgcaga atcggcacaa
     9061 acacttcgtt cagtgcgaca cccagcaccg cgggctcatc tggcggacgc ccggtatagg
     9121 tggaatggta aatcgcatct tcacgctggg taatatgcgt cacggtaaat accgggaaac
     9181 tatcgacttc attatagtaa ccggtgtggt cgccatacgg cccttccggc gcagtttcgc
     9241 cttgttcgat atacccttcc agcacaatct ccgcactggc gggcacttca agatcattgg
     9301 agatacactt caccacttcg gtcttggtgc cacgtagcaa tccggcaaac gcatactctg
     9361 aaagcgtatc cggaacggga gtgactgcac cgagaatcgt ggcgggatcg gcacccagcg
     9421 ccacagaaac cgggaaacgt tcgcccggat gcgccgcaca ccactcctga taatccagcg
     9481 cgccgccgcg atgcgacagc cagcgcataa tcagtttgtt tttaccaatc agctgctggc
     9541 gataaatgcc cagattctgc cgctctttat gtgggccgcg cgtcactgtc agcccccagg
     9601 taatcagcgg cgcggcatct tccggccagc aggtcataat gggaatgcga ttgagatcga
     9661 cgtcatcgcc agagacgatt ttttgttggc agggcgcacc acgcagccgc tttgtcggca
     9721 tgttcaatac ttgcttaaac tgcggcagtt tatcaaacag gtcgcggaaa ccttttggcg
     9781 gctccggctc tttcagaaac gccaataatt taccaacttc acgcagcgcc gaaacatctt
     9841 cctgccccat gcccatcgcc acgcgctttg gcgtaccgaa caggttgcac agcaccggca
     9901 ttgagtagcc tttagggttt tcgaacaaca gcgcaggccc accggcacgc aaagtgcggt
     9961 cagcaatttc agtgatttcc agatgcggat ccaccgggag cgtgatacgt tttagctcac
    10021 cctgctgttc aagcagcgtc aagaagtcgc gtaaatcgtt atatttcatg gcgtccattg
    10081 tagcctctta atctgcgccc attatacggc gttcatcttt gcgatgctgt aaatttgtta
    10141 aattagcgtg aactctgacg gtataacgca aaccggggaa tataattaac ttagcgtaaa
    10201 gcttttgcta tccttgcgcc ccgattaaac ggataagagt cattatgcaa tcctggtatt
    10261 tactgtactg caagcgcggg caacttcaac gtgcccagga acacctcgaa agacaggctg
    10321 tgaattgcct ggcaccgatg atcaccctgg aaaaaatcgt gcgtggaaaa cgtactgcag
    10381 tcagtgagcc attgttcccc aactacctgt ttgtggaatt tgacccagaa gtgattcata
    10441 ccacgactat caacgcgacc cgcggtgtca gccacttcgt gcgctttggc gcgtcgccag
    10501 cgatagtccc atcggcggtt attcatcagc tatcggtata taaaccgaaa gacattgtcg
    10561 atccggcaac cccttatccg ggtgataagg tgattattac cgaaggcgcg ttcgaaggct
    10621 ttcaggccat tttcaccgaa cccgatggtg aggctcgctc catgctattg cttaatctta
    10681 ttaataaaga gattaagcac agtgtgaaga ataccgagtt ccgcaaactc taaaacgcaa
    10741 tcccaaacag tgttttgaca ttagcatccg tggtggcagc cagccatgcg gcatcttctc
    10801 cacgccagtg cgcaatacgt tgcaaaatat ggggcagatg ggctggctcg ttgcgccggg
    10861 atgatggctt tggcgtgaga tcgcgaggga gcagatacgg cgcatcagtt tcgatcagta
    10921 atttttccgc cggaatcaac ggcaaaagtt cccgcagctc cagtccgcgt cgttcatcgc
    10981 aaacccaacc ggtaatgccg atataaattc catgcgccac gcacgcctgc atctcttcgc
    11041 gtgtgccggt aaagcaatga agaaccgcac caggcagttt atccagccac ggctccagca
    11101 atgtcataaa ccgctcgtgg gcatcgcgac agtgcataaa taccggcatg tttaaatctg
    11161 cggcaatgcg tagctgggca acaaaagcgc gttcctgctc ttccggcgtc gaaaagttgc
    11221 ggttaaagtc gagaccacat tcaccaatcg ccaccacttc tggctgcgcg gccagctcaa
    11281 taatcgcttc ttcagtcgca gcttgccact ggctgctgtc gtgaggatgt acgcccgccg
    11341 ttgaccaaca ggacgaatac tgacgcgcca gcttttgcgc ctgctggctt tcacgcaggt
    11401 tagtgccggt gatgagtagc ccattaactc ccgcgtcaaa agcgcacgct acaacatcat
    11461 cacggtcttt cgcaaattgc gaactggtca aattaacgcc gatatcaaac atcctgtact
    11521 ccatatgaca accgccctga cgggcggttg aatttattct tcagtttttt cgctttctgc
    11581 ttcagcgtcg ttttcctctt cccgatttcg ccctttacca acgtaaaagc gtgagaagaa
    11641 gacaccgatt tcaaacagac agtacatcgg gatcgccaac agcgtttgcg agaagacatc
    11701 cggcggcgtc agcaacatcc cgacaacgaa tgcaccaacc agcacatacg ggcgtttttt
    11761 gcgtaagtct tctggcgagg taatccccat ccagcacagc agcacaattg ctaccggcac
    11821 ttcaaaggag acaccaaacg ccataaacag cgccataacg aagcttaaat agctggcgat
    11881 gtcggtggat acctgcaccc cttccggcgc ggtattggca aggaagccaa atgccagcgg
    11941 aaagaccaca aagtaggcga atgccatgcc gatataaaac agcagagagc tggaaaccag
    12001 cagcggcacc accaggcgac gttcatgctt atacagcgct ggggcgataa atgcccacac
    12061 ctgatagaga atcaccggcg ctgacagaat cagcgacacc ataaaggtca gcttgatcgg
    12121 cgtaaagaac ggcgaggcca cgtcggtggc gatcatcgtt gaaccttgcg gcaactgctt
    12181 gatcaatggc gcggatacca ggtgatagat gtcattggcg aaatagacca gacacaggaa
    12241 tatcacgatc accgcgataa tgcagttcag cagacgctta cgcagctcaa tcagatgcgt
    12301 gataagcggt tgagtatctt ctacagacat gtttacggtt tatcactcga cgaaggggaa
    12361 ggtgcagcgg ttttcggttc agcgtccgca gcaggtttta ccaccggctc tggcgtggtt
    12421 tctggcttct gttccggcga actggcctgc gtttgtgcag cggcaggcgt tacgccctca
    12481 tgcgcagctt cattatcttt caccaccggg ttatggatgg tgtgcgcttc atcgctcgcc
    12541 ttttcaggat cgtttgcaac gtaggaacgc ttcatcgact ccgcggcctg gcgtagttca
    12601 tccatcgacg ctttcagttc gggcgtcagg ttagtgaggc tcgccttttc aacctttttc
    12661 agactgtcct gaaactcctg gagttttaac tcctgggtca gttcgttctg caccgttgtc
    12721 gccagtgaac gcaacgcgcg aatccagccc gctaccgttt ttaccgccac aggcagtcgt
    12781 tgcggcccca gaacgacgag gccgatgatg aacaccaata gcagttcgct aaaaccgata
    12841 tcaaacacgg attacacctg ctctttatcg tggcgcttcg cgtcttctgt tttagcctgt
    12901 tcctgattcg tatccgcctg cttatcggcg atagttttcg cagtaaaatc agcatcctga
    12961 ctggttttat cctgctttgg ttcatcatcg ctcattgctt ttttaaagcc tttgatcgac
    13021 gcaccaagat cggaaccgat ggagccgagc tttttggtgc caaaaagcag tacaacgatg
    13081 acggcaataa tcaataactg ccaaatactg ataccaccca tacatgttcc tctgtggtag
    13141 atgatgatta aacaaagccg cattatacgt tacacggccc gccttgagcg atgaaaaaat
    13201 cagcgtgttt tgcgccaacc gacaaaccag gcgatcagac cacctgccat taaccagccg
    13261 ggcatcagcc cccattcagg tcggctgacc aacaagaatg tgccacttaa tactaacgta
    13321 gcgccaattc cgagaaaata acgcgattgt ccctgacgta catgatttga ctgaagctcg
    13381 cgggcaatct tatcaacact gtgctgtaaa tacttgccct ggcgcaaact gtcgtaaacc
    13441 aattcaggca gttctggcat tttttcgacc cagaacggcg ctttttcttt aaatgctctc
    13501 accagcgcag gaataccgac ctgatcttta atccacgact ccaggaaagg cttcgccgtt
    13561 ttccataaat cgagttgcgg ataaagctgg cgtcctaccc cttcgacgta gagcagggtt
    13621 ttctggagta acaccagttg cggctgcact tccatattga agcgacgcgc cgtattaaac
    13681 agatttaaca gtacatgtcc aaacgaaatt tcggccagcg gtttctcaaa gataggttca
    13741 cagaccgtac gaatggcaaa ttcgaactct tcaacgttgg tatctggtgg cacccagcca
    13801 gaatcgacgt gtagctctgc cactttgcga tagtcgcgat taaagaaggc gataaagttt
    13861 tctgccagat agcgtttatc ttctttgttt agcgagccaa caatcccgca atcaatgccg
    13921 atatatttcg ggttttccgg gtgttcatag cttacgaaga tgttgccagg gtgcatatcg
    13981 gcatggaaaa agctgtcgcg aaagacctga gtgaagaaca cctgcacgcc gcgttccgcc
    14041 agcaatttca tgttagtgcc gtttttctcc agcgccgcaa catcagacac cggaatgccg
    14101 taaatgcgct ccatcaccat catcccttca ctacaatagt cagggtaaac ttccgggatg
    14161 tagagcatcg ggctgtcttc aaaattgcgc cgaagctgaa tggcgttggc agattcccgc
    14221 agcaaattca gttcatcaat caatgtcttt tcgtactcgc gcaccacttc ggttgggcgc
    14281 agacggcgac catccggcag caaacgcggc acccagcgag ccagacggta gataagtttc
    14341 agatccgctt taataaccgg caaaatatcc gggcggatga ctttaatcac cacctcttta
    14401 ccattcgatt tcaatcgcgc ggtatgaacc tgggcgatag aagcagaagc cagcggcttg
    14461 atttcaaaat cgtcaaacca cgcttctacc ggcaagccgc ccattgcagc ttcaatctgc
    14521 tgcttcgcca gcttgccatc aaacggagca actttgtcct gcaataacgc cagctgatcg
    14581 gcaatatgcg gtggaaaaag atcgcggcgg gttgataaca tttgcccgaa cttgatccaa
    14641 accggcccca gttcttgcag ggccagtcgt agtcgctcac ctaaaagttt gtctttatgc
    14701 cgatttggca tccagaataa tgagtatcgc catagccgta gcggcagggt gatacgcatt
    14761 ttggggatca gttcatcaag tccgtagctt aaaaaagtgc gaatgatgaa atataggcgc
    14821 cgtacttcac ctggcgtcat ttagcctcca gtttttccag ccgtttggtc agggcatcaa
    14881 cagcacgctc gacggcagcc gtctcttccg caaaccaggc cacttcaagc ggaccgggtg
    14941 ccatacgcca ctcttcagta atggcttccg ccacataacg ttgctggcgc ttaatgccgt
    15001 gatgcaggaa ctttgcgcct ccgcgcatgg ctttgctgat tccttcagcg gcgatatcac
    15061 cggtataagg ggccagcagt tccgcagggt cgaactctgc cagatctgcc agcgcaacga
    15121 agttttgcac cacctgaata tcgccctgca cttccagctc accactgcga atcagtgcgg
    15181 taagctgctg gcgatcgcga agtttcggca acacactggc gtaggcgata acggtgcagt
    15241 cagcatcgcc tgcccattcg cccagtacat caacctggcg ttcgctgaac accagaatca
    15301 atgacgtcga aaagcctttt acctccacgc gcaatacttt acccagcaga cgcgagcggg
    15361 ccgttttcag cgcgggtgag cgatacagga aggtgttgag cagactttca attcctgccg
    15421 tcactaaagg tttaaaaggc atttccggtc tcctgtcaga acttataacc acgatgcagc
    15481 gccacaaccc ctgccgtcag attgtagtag tcgacacttt cgaatccggc atcctgcatc
    15541 atggctttca gggtatcctg atcgggatgc atacggatgg attctgccag ataacggtag
    15601 ctgtcggcgt cgttcgcgac cagtgagcca atacgcggca gcacatggaa ggagtatgca
    15661 tcataggctt tgctcagcgg ctcgataatt ggcttcgaga actcaagcac cagcaggcgg
    15721 ccgccgggtt tcagcacgcg atacattgaa cgcagtgctt tatctttgtc ggtgacgtta
    15781 cgcagaccaa acgaaatggt gatgcaatca aaggtgttat ccgggaacgg cagcgcctca
    15841 gcgttcgcct gaacatactc aacgttgcca atcacaccga tattacgcag cttctcgcgg
    15901 cccattttga gcatggattc attgatatca gcaaggacca ctttgccagt ttctccgacc
    15961 aggcgggaga atttcgctgt caggtcgccg gtgccaccag ccagatccag cacggtctgc
    16021 ccacggcgta cgccgctgca atcaatcgtg aatcgcttcc acaaacgatg aataccaaat
    16081 gacatcaaat cattcatgac atcgtatttt gatgccacgg aatggaaaac gtgggcgacc
    16141 atatccgctt tttgttcctt cgcgacggtc tgaaaaccaa agtgcgtcgt ttcttgtgac
    16201 ttatccacca tctcaatgcc tgctcatcaa aaaattgttc cagaagtgta acagattggg
    16261 cgtcgatgcc ctagatttct acccggctta actactccca atgggctagc gcgactgctg
    16321 attatattca tcatcgcgtt gataagcttc atcattcggc tgctccggaa ccgaccgaag
    16381 tcgatactct tcatcctggc tcaccgcctg ttcagccaaa tccggattaa tctcgcgttt
    16441 aatttctact cctaaaccgc gaaacgcttc tgcctgcgcc agcacatttc cgcgccctga
    16501 agagagtttt ttcattgcct gccgataatt atcctgcgct ttgtcgagac tttgaccaat
    16561 cgcggacatg tcatcgatga acaaacgcat cttgtcgtac agcttgctgg cacgatcggc
    16621 gatttgctgg gcgttgcggc tttgatgctc ataacgccac aggttggcga tagtgcgcag
    16681 cgccaccagc agcgtagtcg ggctaaccag catgatgttg tttttcaacg cttcggtgat
    16741 cagctccggc tggcggtcaa gcgccagtaa aaaagcgggt tcaacgggaa taaacatcag
    16801 cacgtaatcc agagttcgta gccccggcag ctgttgataa tctttgcgtc ccagcaaacg
    16861 gatatggtta cgcaccgacg cgatatgttc ctgtagcgcg ctttcgcggg tgtagtcgtc
    16921 ttcggcgtta aaatagcgtt cataggcgac cagcgtcatt ttggcgtcga tcaccacatc
    16981 ttttccctgc ggcaggcgca cgatgacatc cggctgcatc cgcgagcggg cgtcattttc
    17041 gatgctgacc tgggtttcat attcataccc ttcacgcaga ccggaagcct ccagcacccg
    17101 cgtcaatact acctcgcccc agttgccctg ggttttattg tcgcctttca gcgcgcgcgt
    17161 caggttgatc gcttcctggg ccatttgcgc gttgagttgc tggagattgc gaatttcgtg
    17221 ggtcagggta tggcgttctt gtgcttcttt accgaagctg tcctgaacct gacggcggaa
    17281 accgtccagt tgttcacgta gcggcgacaa caggctgttc agactctgac ggttttgctc
    17341 atcaacccgg cgattgctgt gctcaaaaat acggttggcg aggttttcaa actgctcact
    17401 gaggcgctgc tcgctgttaa tcatctggcg aattttatcg tcagcatgtt gctgtgcggc
    17461 ttccatccgc gtggttactt cacgcagatc ggcctccaga gaggtgttaa tactttgcag
    17521 gctgcgcact tcgttattga gtaactcgca ctctgcacgc cagtgctcgc tttgggtaat
    17581 ttgttgtttt gccgcgctta actccgcgac catctcttca cgttcagcta attgctcggc
    17641 tttttgctgc gcatgttgat aactggcaaa cagccagcca attgccacac ccaccaacgc
    17701 aataactgcg taaaccatga ttgagaaatc cacaacgcct cctgacgcaa caacttaccc
    17761 gcacaaaata gaattgtgct gtacaaacgt ccagttggaa aggcatttcc tgcgaggcgc
    17821 tacgcaaaaa tacaaaaggc cgaacgcgtc ggccttcaga caggagaaga gaattacagc
    17881 agacgacgcg ccgcttccac cacgattttc accgcatggc tttcggtttg tttcatcgtc
    17941 tcagcattcg ggatctcttg ctgggtgcgg ttaacgataa cacccgctac cataccggca
    18001 cgcaggccct gacttgcaca catggtcagc agggttgcag attccatttc atagttcatt
    18061 acgcccatcg cctgccactc ttccatagaa cctttaaagt gacgaactac gcgaccagag
    18121 taagtatcgt aacgttcctg acctgggtag aaggtatcag aagaagctgt cacgccaacg
    18181 tgagttgtcg cgccaatgga tttcgcagct tcaaccagcg cagtcgtaca ttcgaaatca
    18241 gcgacagccg ggaattccag cggtgcgaag tgcaggctcg cgccatccag acggacagac
    18301 gccgtggtaa ccaggacatc acccacatta atatgcggct gaatagcgcc cgttgtaccg
    18361 atacgcagga aggtgcgaat gcccagctgt gccagctctt caacagcaat agaggtagac
    18421 gggccgccga taccggtaga gcagacgata acaggtttac catccagctc tgcacgccag
    18481 atagtgaatt cgcggtgaga tgccagctta accggcttat ccatcagcgc ggcgatcttt
    18541 tccacacgat ccgggtcgcc agggacgatg gcaagcgtag ccccttgtaa atcgttttta
    18601 gtgaggccga gatgaaaaac atcagacttg gacatataca actcctctgt gaatcggttt
    18661 agtcagaaga agcaaaaaga cactttaccg aagggtttaa cattttttcg tgatactcat
    18721 caccatgacg caaatgcgtt gcataaattt acccaccaaa agtgatgcaa atcacataaa
    18781 tcacccttca ttctgcagga ctgcataaaa gatgagccga ttcaggcaat gtgatttgtt
    18841 gcatgctgac tatagttaac attgcgcaac atttttataa gggtacggag aataccatgg
    18901 caacaacaca acaatctgga tttgcacctg ctgcatcgcc tctcgcttcg accatcgttc
    18961 agaccccgga cgacgcgatt gtggcgggct tcacctctat cccttcacaa ggggataaca
    19021 tgcctgctta ccatgccaga ccaaagcaaa gcgatggccc actgccagtg gtcattgtag
    19081 tgcaggaaat ttttggcgtg catgaacata tccgcgacat ttgtcgccgt ctggcgctgg
    19141 aggggtatct ggctatcgca cctgaacttt acttccgcga aggcgatccg aatgattttg
    19201 ccgatatccc cacgttgctt agcggtctgg tagcaaaagt gcctgactcg caggtgctgg
    19261 ccgatctcga tcatgtcgcc agttgggctt cccgcaacgg cggcgatgtt catcgtttaa
    19321 tgatcaccgg attctgctgg ggtggacgta tcacctggct gtatgccgcg cataatccac
    19381 agctaaaagc cgcagtggcg tggtacggca aactgacggg cgacaagtcg ctgaattcac
    19441 cgaaacaacc tgttgatatc gcaaccgatc ttaacgcgcc gattctcggc ttatatggtg
    19501 gtcaggataa cagcattccg caggagagcg ttgaaaccat gcgccaggcg ctgcgggctg
    19561 ctaatgcgaa agcagagatt atcgtgtacc cggacgccgg gcatgcattc aacgctgatt
    19621 atcgcccgag ctatcatgcc gcatctgcag aagatggctg gcagcgtatg ctggaatggt
    19681 ttaagcagta tggtgggaag aagtcgctgt aatgagaaaa gaccgggtgg tattaccacc
    19741 cggtttggat tttacccccg acgcaagttc tgcgccgcct gcaccatgtt cgccagtgcc
    19801 gcgcgggttt ctggccagcc gcgcgttttc aggccacagt ccgggttgac ccacaggcgc
    19861 tctgccggaa tgcgttttgc cgctttcttc agcaaggctt caatccattc cacgctcggt
    19921 acgtttggcg agtgaatgtc atagacgcca ggaccgattt catttggata atcaaactct
    19981 tcaaacgact ccagcaactc catgtcggaa cgcgaggttt cgatggtgat gacgtctgcg
    20041 tccagcgccg caatcgaatc catgatgtcg ttgaactcgc aataacacat gtgagtgtgg
    20101 atttgtgtgt catctttcgc cacggcggcg ttgatacgga aggcctctac gccccactgg
    20161 agatacgcat cccagtcgct acgacgcagc ggtaaacctt cgcgcagcgc cggttcgtca
    20221 atctggatga tgccaattcc agcggcttcc agatcggcca cttcatcacg cagcgccagc
    20281 gcaatctgtt tggcgatggt ttcacggctg acatcttcac gcgggaacga ccagcagagt
    20341 atggtcaccg gccccgtcag catccctttc accggtttgt cggtcagcga ttgcgcatac
    20401 ttcgcccact ccacggtaat cggtgccggg cggctaatgt caccaatgac aatcggtggc
    20461 ttcacgcagc gggaaccgta gctctgtacc caaccgtttt gcgtaaagac aaatccgtcg
    20521 aggtgctcgc caaagtattc caccatgtca ttacgctcgg cctcgccatg taccagcaca
    20581 tccagtccca aacgttcctg ctcaacaatg gcctgcttga tatgttccgc aatgcccgtg
    20641 cggtagttgt tggcgtcgag attgcccttt ttgaaatcca gacgcagggt acgaatttcc
    20701 gtggtttgcg ggaaggaacc aatcgtggtg gtcggccacg ctggcagttt aaaacgcgca
    20761 cgctgggctt cagcacgcac ttcatagaca ttcgcacgct ggctgtcctg ggcggtgatc
    20821 gccgccagac gcttttctac cgccggatta tgtacgcggg tagagtgacg acgtgcctga
    20881 atcggggcgc tccactctgc cagagctgcc gtgtcaccac tgttcagcgc atcgcgcagc
    20941 agtgccagtt catggcattt ttgtagggcg aaggcaaacc agcttttcac ttctgcatca
    21001 agacgcgttt ccacgctcag gtcgatgggg ctgtgcagca acgagcagga agatgccacc
    21061 cacaaatcac gtttgccgac aatgtcctta atttgcgcat atttctcggt aagatcggcg
    21121 cgccagacgt tacgaccatt gatcagaccc gcagacagca accagtcaga aggcaggcgc
    21181 ttgtgcagtt cagcaacgtc atctttacca tgtacgaggt caacatgcag accctgaaca
    21241 ggcagcgcag taatcgtgtc gagatttggc gttacgcctt caaaataggt ggtcagcagc
    21301 agtttcacct gtccctggag cgcgtcgtaa gcgggtttgt atgcgtccag ccacgcctgt
    21361 ggtagttcca gtaccagcgc gggttcatca atctgtaccc actcgatgcc gcgtttcgcc
    21421 agttctgcca gcacttgctg ataaaccggc agaatgtcgt tcagcaggct caggcggtca
    21481 aattgttcac ctttcacttt ccccagccac agccaggtaa ccggccccag cagcacaggt
    21541 ttcaccttgt ggcccagcgc cagcgcctcg tccacttcgt ccagcagctg cgtccaggtc
    21601 agtttgaact gttggccttt aacgaactcc ggcaccatgt agtgatagtt ggtgttaaac
    21661 catttggtca tttccgctgc cgccgcaggt tcgccagtcg gcgcacgtcc acgaccaata
    21721 cggaacaggg tgtcgatatc taccgaacca tctttgttct gatgacgcgc cggaacgtta
    21781 cccagcagca gactggtggt cagtacatga tcgtaccagg caaaatcgcc caccggcagc
    21841 aggtcgatac ccgcttgctt ttgttgatcc cagtgacgag cacgcaattc acgccctacc
    21901 gccagcagtt cttcacgcgt ggagttcccc gcccaataac tttcttgcgc ttttttcagc
    21961 tcgcgacgca ggccaacgcg agggaaaccg agggtgtgat tcaatattgt cattttttct
    22021 tcctctaatt atatgtaaat cctatggatt ttgaatttag ggaaggcggc aagtttattc
    22081 atccccggga gcttactgaa gtaagtgacc ggggtggaga aacgcagcca acgcaccata
    22141 aatttaaaag acgaaggatt ttagccgtcc agatgtttac acatccataa ttggcggtta
    22201 ctgtatattc ctcaagcgca aattattcat gccgaagtga aggactttca tgatcgaagt
    22261 aaaacacctg aaaacgctac aagcgttgcg gaactgcggc tcgctcgcag ccgctgcggc
    22321 gacgttgcat cagacgcaat ccgccctgtc tcaccagttt agcgatctgg aacaacgcct
    22381 tggcttccgg ctatttgtgc gtaagagcca gccgctacgc tttacaccgc agggagaaat
    22441 cctgttgcaa ctggcaaacc aggtactgcc gcaaattagc caggccctgc aagcctgcaa
    22501 tgaaccgcag cagacgcgtc tgcgcattgc cattgagtgc catagctgta ttcagtggct
    22561 gacacccgcg ttagaaaatt tccataagaa ctggccgcag gtagagatgg attttaaatc
    22621 gggcgtgaca tttgacccgc agcccgcctt gcaacaggga gagctggatc tggtaatgac
    22681 gtccgatatt ctgccgcgca gtggcctgca ttattcgccg atgttcgact atgaagtgcg
    22741 tctggtgtta gcacctgacc atccactggc ggcgaaaacg cgaattacac cggaagatct
    22801 cgccagcgag acgctattaa tttatccggt gcagcgtagt cgactggatg tctggcggca
    22861 ttttcttcag ccggcaggcg tcagcccgtc actgaaaagc gtcgataaca ccttattgtt
    22921 gattcagatg gttgccgcgc ggatgggtat tgccgcgcta ccgcattggg tagtagagag
    22981 ttttgagcgc cagggtctgg tggtgaccaa aaccctgggc gaaggcttgt ggagccgact
    23041 gtacgccgcc gtgcgcgatg gcgagcagcg tcagccagtt acggaagcgt ttattcgctc
    23101 agcgcgcaat cacgcctgcg atcatctgcc gtttgtgaag agcgcggagc gacccactta
    23161 cgatgcaccc acagtgaggc caggatcacc agcgcgcctg taataaacgt tggccagtgc
    23221 ggctgttggt gccagatagc caggtttacc agcagccctg ccggaacgtg catattattc
    23281 ataatgccca gcgttccggc gtccacctgc gtcgcgccgt agttccacat aaagtagcca
    23341 atcccggaag ccaccacgcc aagaaacacc agaatgcccc attgcagcgt ggtttgcggc
    23401 attttctgcg catttcccag caagaaccat gcaatcactg ccaccagaaa cgcgccaaga
    23461 tagaaccacg caaaggcgtt atgctgtggc atcgggcgag tttccatcag gcgtttgtaa
    23521 cccaccatgc caatggcaaa agtgatattg gagagttgca ccagcagcaa gccagtccag
    23581 aaatggtcgg tgacctgatc atagcgaata atcccggcac caatcaccgc cagcaaggcg
    23641 ctaaaggcat agccccagcg cagacggcgc ttactcatga tgtcataaat cagcgtgatg
    23701 tagagcggcg tcagcacggt gaacagcagc agctcggaaa ccgtcaggta gagataagcg
    23761 cggaaactca gcatatacat cacgccaagc tgcatcgcgc ccaccagcat atacaggccg
    23821 accgttttca ggctattgcc acgggtacgc agaaacggca gaaaaacgag tgccgccagg
    23881 ccaacgcgca ccagcaccgc aaaatagcta tcgacgtgcc ccgcaaggta ctcgccataa
    23941 aagctaaagg agaaggccca cagaatcgtg gtgatgataa gtagcgccac aatggaaaac
    24001 tctttgatta acgggtatcc attgtagcga agtatcaggt tgacaactga ccaaataaag
    24061 aacgattacg ataaatagag tttacgcaga taatgcggca ccgcgtcgtc ggcattagta
    24121 ccaatcactt ccagctcggg atgaaggtct ttcagacgct ggtgcgcact gcccataatg
    24181 cagcctttcc ccgccatcga cagcatttcg gcgtcgttca tcccgtcacc aaacgcaata
    24241 caatccttca ggctgtagcc cagtttcttc gccaccgctt ccagcgcatg gccttttgaa
    24301 acgccgcccg ccatcacttc cagacaggtt aaggtagaga aactgacgtt gacgcgatcg
    24361 ccccaacgag cgttaatcgc ctgctccagc ggcagcagtt gttcatggga atcgcaggtg
    24421 aagaacactt tgctgacgcc ttccggctcc agtaatccag gctcatacag cgcatattgg
    24481 aacaccgctt ctttaaaaaa gcgcatctct tccgggcgat ggcgattcat aaaccattcg
    24541 tcgtcgcgat aaacgttagt aatgatgtcc ggattgtcgt tgactacgcc aaacagatcg
    24601 ctggcaatgt cgcgatccag gttatgagca aaaatcagat taccatccag atcgtgaacg
    24661 cgcgcaccat tggaggtaat catgtaagac ttaatctcca gattatcgcg aatttgcccc
    24721 acatcaacgt ggtgacgacc ggtcgcaaac acaaagttga tgccgcgcgc ggtgagcagc
    24781 ttcagagttt ctttggcgta aggggataac gtatggtcgg gagaaagtaa cgtgccatct
    24841 aaatcagacg caacaacctg gtacataaga aatttaaacc tctgtagagc ggtttccgct
    24901 gggtgagtta tgcctgttga aaaaatcaac gatggcgtgg agcgcgactg agcgcattgc
    24961 gtccttttca aaaaggatct catggtaagc acctttaatt accaacggcc gtcctccttc
    25021 gacaggatgg cccgcggcgg tgcggagttc acaaaaacgg tcatgcatgc ggttatccac
    25081 cacgcgttcc tcttcagcct gcaagagaag cgttggcgtg gcgtcatcac ccgcaccggc
    25141 taacacctgt tcgccagcca gaatactttc gcgtacccaa tggtaggtcg gcccaccgac
    25201 gcgaatcgtt gggtcatcag catagaagcg taagttacgt cgatatcgct gtctgctgtg
    25261 ggtcagtacg ttgatagcaa acggcaacgc gcgccagcgc ccggtgccta ttgcatagcc
    25321 atcacggaaa cgtggatgcg cttcggccca gttgaggatc tgccgtgcca taaatgacgg
    25381 catacgaatc acgatcccaa acattggcgc agttagcgca atggcgtcac atacacctgg
    25441 atggcgttgc agaaataatg tggagatcgc accgcccatc gaatgtgcca gtatatagcg
    25501 tttacgccac ggaccgggct gaacctcctg ctgccagaat gccgccagat catcaacata
    25561 atcattaaag cgattaacat gcccgagatg cggatcggct aacaggcgac cggaacgtcc
    25621 ctgcccgcga tggtcgatga ttaagacatc aaaccccaaa tggaacaggt cataggccag
    25681 ttccgcatat tttacgtagc tctcaatacg ccccgggcag atgactacca cccggtcatg
    25741 gtgctgtgcg cgaaaacgga caaagcgcac cggaatgtca tccacaccag taaactctgc
    25801 ttcatcacgc tgacgccaga aatcagtcag cggtcccatg gtaaaagcag caaacgcgtt
    25861 ttctcttgtt tcccagtctt tttgctgctg aaacatcggg taatctgcct cttaaaccac
    25921 gtaaaatcgt tttttttagc gtgcctgaca caacgctgcg acagtagcgt attgtggcac
    25981 aaaaatagac acaccgggag ttcatcatga ccttagaatg gtggtttgcc tacctgctga
    26041 catcgatcat tttaagcctg tcgccaggct ctggtgcaat caacactatg accacctcgc
    26101 tcaaccacgg ttatcgcggc gcggtggcgt ctattgctgg gcttcagacc ggactggcga
    26161 ttcatattgt gctggttggc gtggggttgg ggacgctatt ttcccgctca gtgattgcgt
    26221 ttgaagtgtt gaagtgggca ggcgcggctt acttgatttg gctgggaatc cagcagtggc
    26281 gcgccgctgg tgcaattgac cttaaatcgc tggcctctac tcaatcgcgt cgacatttgt
    26341 tccagcgcgc agtttttgtg aatctcacca atcccaaaag tattgtgttt ctggcggcgc
    26401 tatttccgca attcatcatg ccgcaacagc cgcaactgat gcagtatatc gtgctcggcg
    26461 tcaccactat tgtggtcgat attattgtga tgatcggtta cgccaccctt gctcaacgga
    26521 ttgctctatg gattaaagga ccaaagcaga tgaaggcgct gaataagatt ttcggctcgt
    26581 tgtttatgct ggtgggagcg ctgttagcat cggcgaggca tgcgtgaaaa ataatgtcgg
    26641 atgcggcgta aacgccttat ccgacttact ctgaagacgc gtctggcatc accgcgaaat
    26701 aatcaaatga atgccaaatc cggcaaataa cgccccggca aaaccatcaa tccacttcgc
    26761 cagacgttga taaccacggc gcatttgcgg cagggcaaac aggctggcaa cgacggtaaa
    26821 ccacgccagc gtttcgacaa tgatcagcgc aaaaatgccc cagcgcgcgg tagtgccaac
    26881 gttatcaccg acaaacaatg agaacaccga gccaaagtag ataatcgctt tcggattagc
    26941 gagattggtc agtaaacctt tcaggaaact gcgcccactt ttcgccagct cgacctgtgg
    27001 cgcaggtgca gaaaccgcct cttttttcag tgcaccacgt agcatctggt aacccatcca
    27061 gcagagatac aggccaccgc ccaccataat cagcgtatgc agccaggcca ttttttcgat
    27121 aatcaaatgc aggccaagca gcgcaatccc agcccaaacc attacgccgc aggtaatgcc
    27181 cagcacgccc atcatcgctt ctttacggga acgactgaca gcggtctgag agacaaaaaa
    27241 gaaatcggga ccggggctca taagcgccac aatgtgcacc atggcgacgg tgagaaataa
    27301 catcaacata catttgactc gcgggggaaa cgtttacgga gtcttcatac tggcactttt
    27361 ttatgctgct gactactctt cgtcatcgcc atcaacatgc gcacgaatca gcgccataaa
    27421 cggtttgcca aagcgttcca gcttgcgcat cccaacgccg ttaacgctga gcatttcgct
    27481 ggcggtgatc ggcatctgtt cagccatctc aatcaaggtt gcgtcgttaa acaccacgta
    27541 cggcgggaca ttactttcat cggctatcga tttacgcagt ttgcgtaatt tggcgaacag
    27601 tttgcgatca tagttgccgc cgaacgattt ctgcatcgct ttcggtttga gcgccacgat
    27661 acgcggcacg gcaagttgca aagaggattc gccgcgcagc accgggcgcg cggcctctgt
    27721 cagttgtagg gcagaatgct gggcaatatt ttgcgtcacc aggccgaggt gaatcagctg
    27781 gcggatcacg ctcacccaat gttcatggct tttatcacgg cccatgccat agactttcag
    27841 tttgtcatga ccatagtcgc ggatacgctg gttattagca ccacgaatca cttccaccac
    27901 ataacccatc ccaaaccgct gattcacacg accaatggtg gaaagggcaa tctgagcatc
    27961 ggttgaaccg tcgtactgtt tcggcggatc gaggcagata tcgcagttcc cgcacggctc
    28021 ctgacgccct tcgccaaaat agttcagcaa taccagacga cggcaagttt gcgcttcggc
    28081 aaacgcgccc atcgcattga gtttgtggcg ctcgatatcc tgcaactgcc cctgcggctt
    28141 ctcttccaga caacggcgca gccacgccat atcagccgga tcgtaaaaca gcatcgcttc
    28201 cgcgggcagg ccatcacgcc cggcgcgtcc ggtttcctga taataggatt cgatattgcg
    28261 cggaatatca aagtggacca cgaagcgaac gtttggttta ttgatgccca tgccgaacgc
    28321 caccgtcgcc accacaattt gcaggtcatc gcgctggaat ttttcctgca catcggcgcg
    28381 aacattattt tccagcccgg catgataggc cgccgcgcta attcccttgc tttgcaggcg
    28441 cgcagcggtg tcttctactt tcgcgcggct gttgcagtag ataatgcctg acttaccgcg
    28501 ctgttcctgc acgtagcgca tcaactgatc gagcggtttg aacttctcca tcagcatgta
    28561 gcgaatattc ggacggtcaa aactgctgat ttgaatcagc ggatcgttca gccccagcag
    28621 gcgcacgata tcctggcgcg tggtgtcgtc ggctgtggcg gtcagcgcca taaacggcag
    28681 cgtcgggaac cgctggcgca actgaccgag cgcggcatat tccgggcgga aatcgtggcc
    28741 ccattgggag atacagtgcg cttcatcaac ggctaataac accggattcc agtgcgccag
    28801 atgctcaaga aagttatcca gcatcaggcg ttccggggcg atataaagca gacgaatttg
    28861 cccggtgcgg cagcctgtca tcacttcaag ttgctgttcg cgggtttgcg tcgagttaag
    28921 gcacgccgcc gccacgccgt tggcttgcag ttgatccacc tgatctttca tcaacgaaat
    28981 cagcggtgaa acaaccacgg taaggccgtt tagcaataag gcagggattt gatagcaaag
    29041 ggattttccg ccaccagtgg gcatgacgac gaggcaatcg cggccggaaa gcacagtgtc
    29101 gataatttct tcctggccgg ggcgaaactg ttggtagcca aaggtttctt gtaaaacctg
    29161 tttagctccg gactccagat tcaacacttc cgcctgcgcc acattcaccc cgattgcctg
    29221 aaataaaaac aggcgctatt ttcagcgcct gcgcgagaaa ctgcaatgct tttagtctct
    29281 gagagggtaa tcctggatgc tggattccag atttgccaac cactcaaccg ttcatcaaaa
    29341 caaatcgttt agcataaccc ccacaccgac acgggtctgg ttgaagttat agtcgatgag
    29401 cgattcgcca tagccgctgt aaacctgagt ataaaggcgc acatgtttgg tgatcgggta
    29461 acttaagcct aactccgcgc cgccgtagcc ggtgttccag ttgtactgtc ctttcgcact
    29521 gagcaccgca tcaccgaggt gatagccgat tttaagctgg tagtaaccca tatatttggt
    29581 gatatccggg ttatcgtcag tattacccac cacataccac ggcttcactt ctaccagcca
    29641 gttaccgttt tctgccatca ggcgagtata aaggcggttc cagctgcggg aggtcgggtc
    29701 ggaacgcccg ttagagtcgt ggttataccc catctccaca tcgcgcagcg tccaacctgc
    29761 aaaacggtaa tcggtggcaa aaccgaggaa caattgcggt tcgtagttgg tttcacgaaa
    29821 cggtgaagac tcttcgctat tggacagttg ccaccaggat ttttgcgtat aagacgcacc
    29881 caacaccgag ttcgggccta aaatcccacg ccacagcgga aatgccaggc tcaactgaaa
    29941 ctttacttca tccttacgcg cattttccgc ccagtcgtaa ctggcaatcg cttctttatt
    30001 cagatcgctg gtttgggtgt aaatgaggta gttggtgtca taaggataga gcgtgaacgg
    30061 attgtcatgc tcctgcagca tattggcgat aatactgcca cgcaccgctg gcgcgtcatg
    30121 cacctctttc accgttgcct cttgtgcata tactgccata ggcaacataa acaccggcaa
    30181 caaccagccc tgcagagtcc gcatcggtcg tgttctccgt aacgaattat tgataaggtg
    30241 aatatttttc tgcgggctat tttacatact taactccata gccgttagtt atcccttcct
    30301 aaagtagaaa ccaacaacaa agaagcataa aatcaacatt tcattaacca atgaagtgta
    30361 aggatgatat gtctgccgta ctgaccgctg aacaagccct gaaattagtg ggtgagatgt
    30421 ttgtttatca catgccattt aaccgcgcat tggggatgga actggagcgt tacgaaaaag
    30481 agttcgcaca gctggccttt aaaaatcagc caatgatggt gggcaactgg gcgcaaagca
    30541 ttttgcacgg cggggtcatt gcgtcggcgc tggatgtcgc cgccggtctg gtgtgcgtgg
    30601 gaagtacctt aacccgccac gaaaccatca gtgaagatga actacgccag cggctatcgc
    30661 ggatggggac cattgatctt cgcgttgatt atctgcgccc aggcaggggc gagcgtttta
    30721 ctgctactag tagcctgttg cgtgcaggca ataaagtcgc cgtcgcccgc gttgaattac
    30781 acaatgaaga acagctttat attgccagtg ccaccgccac ctatatggta ggttgaagac
    30841 ataaaagcag gtaaactgct gttaccaatt aaaaatgagt attcccgatg gatgcaaaac
    30901 aaacgcggca gggcgtatta ctcgctcttg ccgcttattt tatttggggt atagcgccag
    30961 cgtacttcaa gttgatttac tacgtgcccg ccgatgaaat cctgacgcat cgcgtgatct
    31021 ggtcgttttt ctttatggtg gtgctgatga gcatttgccg ccagtggtcc tatttaaaaa
    31081 cgctgattca gacgccacag aaaattttta tgctggcagt ctctgccgtg ctgattggtg
    31141 gcaactggct actgtttatc tgggcggtga acaatcacca tatgctggaa gcgagccttg
    31201 gttactttat taacccgctg gtgaacattg tgctggggat gattttcctc ggcgagcgat
    31261 tccgccggat gcaatggctg gcggtgattc tggcgatatg tggcgtgtta gtccagctgt
    31321 ggacttttgg ttcgctacct attatcgcgc tgggactggc atttagtttt gccttctacg
    31381 gtctggtacg caagaagatt gccgttgaag cgcaaaccgg catgttaatc gaaaccatgt
    31441 ggctgctgcc cgtggcggca atttacctgt ttgctattgc cgacagctca accagccata
    31501 tggggcaaaa cccgatgtcg ctgaatttac tgctgatcgc cgccggtatt gtcactaccg
    31561 taccgctgtt gtgttttacc gccgctgcca cgcgcttgcg tctctcaacg ttaggctttt
    31621 tccagtacat tggcccgacg ctgatgttcc tgctggctgt gacgttttat ggtgaaaaac
    31681 cgggtgccga taagatggtg actttcgcct ttatttgggt ggcgctggca atttttgtga
    31741 tggatgcgat ttatacgcag cgtagaacgt ccaaataaaa aataaatata ttctgaaaaa
    31801 atatgccgac tcttgcatga gagtgggcat attgccatgc tgaccggaga ctcatacaag
    31861 gatgtaaaat ttatgttacg catatttatc ccaacatcta acggtaagat ttccagacgt
    31921 cgttatatat tttcatttat tttaataaat ttcatttttg cctttcttat tatctttttt
    31981 aacgatggag aagcaggctt tcttgttata gtctctacca tcgtactcca ttatctcgtc
    32041 atcaacatga attgccagcg actccgtgat agtggtttca tctatataaa aacttatgtt
    32101 tttggtacat tagcagtata tatcatctct atcatcacaa tgatagccga agattttgcc
    32161 tgttcaggca atggttcgat gatttttttg atttgttatt tttccacttt cagtatgcta
    32221 atgcttgcac ctactgattc atcaaaacaa tagttatgga gtatttatga gtaaggaata
    32281 tatgaacgat ggttcattaa gtgaaaaatg gaaataccga tttaattttt atgatcaaca
    32341 tggttttcct ggattctggg gggcaacacc agaatataaa gcagcattta aagcattaaa
    32401 agtaagacaa cgcttaacta ttcaaatgaa tttcattgct ttcttctgtt cctggatata
    32461 tttatttgtc ctggggttat ggaaaaaagc aattatagtt ctattacttg gtattctatc
    32521 tctatttgtt ggtgcactaa ttggcgttaa cattctggga attgccgtag cagcctatgt
    32581 tgctgttaac acgaacaaat ggttctatga gaaagaggta aaagggttaa atacctggag
    32641 cctttgaata acaggtggct tagccagact aagccaccgc tctcgttttt tacaaccagt
    32701 tcttccgctt aaagtacaga tacggtgcca ggcccgcgag gatcataaag ataatcgcgg
    32761 cagggtagcc gaagctccac ttcagttctg gcataaactc aaagttcatg ccatagctgg
    32821 aagcaacgag cgtcggcggc aggaatacca cggataccac cgagaagatt ttgatgatgc
    32881 ggttctgctc gatgttgata aaacccattg ccgcctgcat caggaagttc accttctgga
    32941 acagggattc gttatgcggc agcagggatt cgatatctcg caggatttca cgcgcctgct
    33001 ccagttgccc acccggtaaa cgcgctttac gcaccaggaa gttgagcgcg cgctgggtat
    33061 ccatcagaca caggcgaact ttccagccga tatcttccag ttccgccaga gtggagagcg
    33121 cctcgtcgta ctcatcgccc tgatgccctt ccataatcac ccggctcaac tgctccaggt
    33181 cgctatagat attttcaatt tcatctgcca actgttcgat tttggtttcg aacagatcca
    33241 gcagcaactc gtaggcgtta ccgtctacca tcgactggct acgggcacgc atacgataca
    33301 gacgaaaagc gggcagttca cgctcacgca gagtaaacag acgaccatca cggatggtaa
    33361 atgccacagt ggagttaccg gcgtgatctt ccgcatcttc aaagaagaag aaggagtgaa
    33421 tatgcaggcc gtcgtcgtct tcaaagaaac gtgccgatgc ttcgatgtct tccagttccg
    33481 ggcgggttgc caggctctgg ccaagttcag attgtacgcg cagtcgctcg tcgtcgtccg
    33541 gttcgacaag atcaatccat actgcattta caaggggttg tgactcttcg acttccagcc
    33601 gggtcagtcg gttattttcc agttgaaatg cgctcagcat gaccgggact cccaatgctt
    33661 aaaatatcgg acagttcggt gggcacacag aaacaaattg ggtttcagac cattaaacag
    33721 cctgactcag cgcgacggga aaaattgagg tcgctgacaa ccgctaaggc tatcagcaaa
    33781 aagggatagc cttaggagtt gatcctggat gacaggatag tgagccagta tctactgggt
    33841 gtgtccaagg cgaatgtcct cttagagtga tcgtgcgcgc atgttacgcc agcaaaattt
    33901 tgccgtcaac acgcaacaga acaccacaga acaatagttg aacttcgcgc tttttggtac
    33961 tcgtcaaggt cgctaacagg ataaaaaaat cccacatcca ggacctataa tggcgcatca
    34021 gctactcatt ggtaaaggaa tgatcacctt gaatctcaaa cggatttttc tcgccctcac
    34081 cttacttccc ttgtttgctg ttgccgctga tgattgcgca ctctcagatc cgacgctgac
    34141 cgtacaggcg tataccgtta atcctcaaac agagcgggtg aaaatgtact ggcaaaaagc
    34201 caatggcgaa gcgtggggaa cgttacatgc tctgctggcg gatattaata gtcagggtca
    34261 ggtgcagatg gcgatgaacg gcggcatcta tgatgaaagc tatgcgccgc tcggtttgta
    34321 catcgaaaac ggtcagcaga aggtggcgtt aaatctcgct tcaggtgaag ggaatttctt
    34381 tatccgtcct ggcggcgtgt tttatgtcgc gggagataaa gtcggcatcg ttcgtctgga
    34441 tgccttcaaa accagtaaag agattcagtt tgcggtgcag tcagggccaa tgttgatgga
    34501 aaacggtgta attaatccgc gtattcatcc caacgtcgcc tcaagcaaaa ttcgtaacgg
    34561 tgttgggatt aataaacatg ggaacgccgt gtttttgttg agccagcagg caacaaattt
    34621 ttatgatttt gcctgttatg ccaaagcgaa actgaacgtt gagcagctgc tttatcttga
    34681 tggcacgatt tcacatatgt atatgaaagg cggggcaatc ccgtggcaac gctatccttt
    34741 tgtcaccatg atttccgtcg agcggaaagg ttaaaacgat agttttgtgt cagatactga
    34801 agatggcgca gatgccggat gcggcgtaaa cgccctatcc ggcctacatg acgttgcaat
    34861 ttattgaatc tgaatgattt tttaggccaa ataaggtgcg cagcaccgca tccggcaacg
    34921 ttacaccgac tccagccggg cgtatgccgc caccagccat ttaataccct ggccctgaaa
    34981 tgccacctgc aaacggctat gctcaccgct gccttccata ttgacaatgg tgccttcacc
    35041 aaacttagcg tggcgtacgc gctggccgag cttgtagccg ctgtcgttct cgaccatcgg
    35101 cgtacccatc cgctgatggc tgaccgggcg gcttaccgtg gcgcgcaggc gcacctcttc
    35161 cacacactct tccggcagct cgccgataaa gcgcgacggg cgatggtaaa cctctttacc
    35221 atacagacgg cgggtttccg cgtaggtcag cgtcagtttc tgcatcgcgc gggttacgcc
    35281 aacgtaggcc agacggcgtt cttcttccag acgcccgcct tcatccagcg acatctggct
    35341 tgggaacatg ccctcttcca taccaacgat aaacacctgc gggaactcca ggcctttcgc
    35401 cgagtgtagc gtcatcaact gcaccgcatc ctgccaggta tccgcctgcc cttcacctgc
    35461 ttccagtgcc gcatgggaga ggaacgcctg cagcggcatt aaatcttcgt cttcttcgtt
    35521 gtagctgaac tggcgcgttg ccgtcaccag ttcctctaag ttttcgatac gcgtctgacc
    35581 tttttcgccc ttctcctgct catacatggt acgcaggccg gagtctttaa ttacccggtc
    35641 agtctgtaca tgcagcggca tatcggcagt ttcctgcgct aaggcgtcga ttaattccat
    35701 aaatcgctgc aaggcgctgg cagctcgccc ggcgagggct ttttcctgca acagctcacg
    35761 acatgcctgc cagagtgtta actggcgatc gcgcgatgtc tgacgtacca cgtccagcgt
    35821 ccggtcacca ataccccgcg ttggcgtatt caccacacgc tcaaaggccg cgtcgtcgtt
    35881 gcggttggca atcaggcgca gatacgagag cgcatctttg atttcctggc gttcgaagaa
    35941 gcgcatcccg ccgtaaatac ggtacggcat actggcctgc aataacgcct cttcgagcac
    36001 ccgcgactgg gcgttgctgc ggtagagaat ggcgcactcg gcaagcgctc cgccgttgtc
    36061 ctgccaggtt ttgatgcggt taaccacaaa acgcgcttca tcgagttcgt taaaagcgca
    36121 atagagggaa ataggctcac cgtccgcgcc atcggtccac agttttttac ccagacgccc
    36181 gttattgttt tcaatcaggg cgttagcggc gctcagaata ttgctggtag agcggtagtt
    36241 ttgctccaga cgaatagttt cggcaccggg gaaatcatta aggaaacgct gaatattctc
    36301 cacctgcgcc ccgcgccagc cgtagattga ctggtcgtca tcaccgacga tcatcacttt
    36361 gccggtgtcg cccgccagca ggcggatcca cgcgtactga atgttgttgg tatcctggaa
    36421 ttcgtccacc aggatattgg taaaacgttc gcggtagtgt tgcaggatat gcggcttgtt
    36481 aagccacaac tcgtgagcgc gcagcagcag ctcggcgaag tccaccaggc ccgcgcggtc
    36541 acacgcttcc tgatacgcct gatacacctt ctgccaggtc tgctccaccg gattaccgta
    36601 gctttgaata tgatgcggac gcaggccttc atctttctgg ctgttgatgt accacattgc
    36661 ctgccgcggc ggccactgct tctcgtcgag gttcatggct ttgatcagac gcttaagcag
    36721 gcgtagctgg tcttcactgt cgaggatctg gaaatcctgc ggcagattgg cgtccatatg
    36781 gtgcgcacgc agcaaacggt gcgccagccc gtggaaggtg ccgacccaca taccgccctg
    36841 gctcgtgccc atcagttgcc cgatacgatg acgcatctcc gccgccgctt tgttggtaaa
    36901 cgtcaccgcc ataatcgagt atggcgagca gttttccacg ctcatcaacc aggcgatacg
    36961 atgcaccagt acgcgcgtct taccactgcc cgcgcccgcc agcaccagaa ggttgctgcg
    37021 tggcgcggcc accgcttcgc gctgtttgtc attaaggctg tcgagcaggt aagaaacgtc
    37081 cattggcacc gccgcgtaaa aataggttgg gcggagaagc gcaacgccct ccgccaaaaa
    37141 gctgggtata tatacagatt tgctgattat atcagcgagg tcagagatgc caaccgggaa
    37201 atttccagat gcggcagtaa acggctgtcc caggtttgca tcagatcgcc attttccggt
    37261 ctgatccaac aagcctgcat tccgctgcga attgccccac ccacgtcagt ggtgagatcg
    37321 tccccaacat gtaagatctc gccgatcggc acgttgagtt tttccgcagc caaaaagtac
    37381 atatcgctga acggttttga gcgcccgtgc gggccagcgc gcagcacaaa ctcaaaataa
    37441 tcccccaaac caaacagctc cggctgggcg ttaccgttgg tgatcgccac cagcggccat
    37501 ttcttcgcca gctgttttaa ggtgtcgtga gtttgctgcg ggacgtcgat tcggctgcgc
    37561 catttggcaa agttgatcat tgctgcgtgt gcgcctgcac tggcttcttc ggcactcagc
    37621 ccggcgtcga gcatcgcttg ttcaatcgaa cgaaaacgcc agcgcgtcac gtcgtgataa
    37681 atctcgggtt ccgcttcccg taccgcctgg cgcaggcgtt gcagatcttc attctggaag
    37741 ctgcgcagcg ccggatgata attttgcaca aaggtaagcg cctctcgctc ggtgcgcaaa
    37801 atcaccggac ggttatcgta aagggtatca tccaggtcaa aggtgagcgc cgagatgcgc
    37861 cccaaaggcc ggtaaaaacg cattatttcc cccgtttggc gcgtggatgc gccgcatcgt
    37921 acaccgaggc aaggtgttga aaatcaagat gagtatagat ttgcgtggtg gagaggttgg
    37981 catgacccag cagctcctgc acaccacgaa gatcgccgct cgactccagc atatgcgtgg
    38041 cgaacgagtg acgtaattta tgcggatgaa cgtgattatt cagcccttgt tttatgcccc
    38101 attcggcaaa gcgtttctgc acattacgcg cggagatacg cttgcccagt ttcgacagaa
    38161 aaagcgcgtc gtcttcgcta ccaaacaggt cgcgcaaatc aagccagtgc tcaatccacg
    38221 ccacagcgtt gcgaccaatc ggcaggcggc gctctttgct gcctttcccc ataacccaca
    38281 cttcaccaga ctccaggtcg aggtgtttaa tatccagccc caccagctca gaaagacgca
    38341 gacccgcgcc gtacatcact tccagcattg cacggtcgcg tacagcgagg ggatcattga
    38401 tatcaatatc cagcagccga ttcatatcgt cgacgtcgat gtttttcggc agatgacgcg
    38461 gcgctttcgg tgccgaaaca cctttcgccg ggttagcttt gagttcgttc tggctgacca
    38521 gccagtcaaa aaagctacgt agcgcagaaa gccgtaacgc cagacttgct gctcccagcc
    38581 ctttacggcg actgcgtaca gcaaaattgc gcaccatcgt cacatcacat tgctgccagc
    38641 tttgcaggcc gttttcgctg gcaaaattga tgatcgcctc aagctgacgc tggtagttaa
    38701 gcagggttat cgggctaagc tggcgctcca cgctcagata acgtaggtag cgttctacat
    38761 cggtgtgtaa atcggtcata cgcgttcaat ccaacgctcc agaagctccg gcaacatcag
    38821 cgcaatttca tgaagtaact gcgttccttg cccttgttga tagtgactgg catcgcgact
    38881 ggtaaacagc acgacaccca aatcagcatc gcttcccagc atcgacatcg ccaccgatcc
    38941 caccgctttc gcttccggta gcaccaccag cagctctggt ccgttaagcg gcccaagata
    39001 gtgctgttcc tgccccaaac gctgaatacg cagcggttcg aaagactgac ggcttaatgc
    39061 cagatgagtg tggttcgacg gcgcacctaa gcgccagcga tccggaaaca ggcgcagact
    39121 cgcacctgcc aggccgagat cgcgcgccca gcggtgaaag cgcatcagca tatcgtcgag
    39181 actgctggcg gcggtgagac tgcgctgcag gtagagtagg cgataaaaca ggccttcgtt
    39241 ggcgatagcc tgttccatca acagcgccat gttctcttcc agaacatgaa tatgattacg
    39301 tgcgcgggcc atgtgccact cgaccaacga aacggtgccg cgtaccggat gcggcacacg
    39361 tatcgcttct actgcgcgcg cattacggat aaaaaactca ggatttttaa tcagataatc
    39421 gacaaccgcc cggtcatcaa gctccgtgag tgtttcctgc agttcttccc ctggttgctt
    39481 catagatgaa taaatccgtc gtagacatgt accgccgggc cagtcatata taacgggtga
    39541 cccggacctt tccaggcgat atcaagacga ccgccgggga gttccacgcg tacttcttcg
    39601 gccagcaaac cttgctgaat ccctactgca accgccgcac acgcgccgct gccgcaggcc
    39661 tgggtttctc ctgccccacg ctcataaacg cgtaaacgaa tatgctcgcg cttaaccact
    39721 tgcataaaac cgatattggc gcgctccgga aaacgctcgt ggctttccag aacaggacca
    39781 agcgtttcta ccgccgcggt atcgacatca tcgacctgaa tcacgcaatg cggatttccc
    39841 atcgacacca cgccgcataa gattgtctgc tcggcggcgc gcataatata ggtcttttcc
    39901 gctttgttag cgcgaaacgg cacggcggaa ggttcgaagt tgggttcgcc catatttacg
    39961 cggaccagat catcatcggt gacggtcaga accatccgcc cgttggcggt gctgacgcgg
    40021 atatcacgct tattggtcag tcctttcaga cgcacaaaac gggcaaagca gcgcgcaccg
    40081 ttgccgcact gcgccacttc actgccatca gcattgaaaa tgcgatagtg aaaatccagt
    40141 tcaggatcat acggcggctc aaccaccagc agttggtcaa accctacccc caggtgccga
    40201 tcagccaggc gacgaatcag ctccggtgaa aaaaagacat tctgcgttac cgcgtcgacg
    40261 accataaaat cgttgccaag gccatgcatt ttcgagaact gcatcattta ctccaatcac
    40321 gcgggtacag aaactgactt ttagtaattc acctgggatg gaccatcgcc agtggcgcga
    40381 tcgtttttat ccggcaccgt ggattgcgtt tgcgtctcta ccggtttggt cggcggcggt
    40441 gcgtttttat ctgcaggcgg gaaatagagc ggacctttca gaccgcagcc cgtcaggctg
    40501 aagagagtaa gtaatacagt gagtgcctta aacacgtttt tcattatgga ttgcctgtaa
    40561 agttcatcgc tttctgcttt ctatcatcgc aggagaagac gtaaaagcaa gcgtttagcg
    40621 actctttatg aagtctgaaa agtgaggaaa tgctgcgagt ataacgctta ctcgtgggga
    40681 tttatgtttt gctggtagtt tcgtgatcgg cacctcgcgc caggatggct ttatgcacta
    40741 tcgcaatgtg gtttgtttgt tgtctttttt agttccgtca gcgtgaggat gctcgctcgg
    40801 taaacctgat cataatgttt accagaaaca gggaaagacg tggtgtaact gcgccctaat
    40861 gaagagacaa atctttcgct acacagagac atcattattc cggtgacgga tgaatcgtgc
    40921 cggaacgcag ccgcagaggt gcaaactttg aagccctgac cccatgccgc tatactgccg
    40981 ccatcactta aaaacaggat acaacaatga acgacagtga atttcatcgc ctggctgatc
    41041 aactctggct gaccattgaa gaacgcctgg acgactggga tggcgacagc gatatcgact
    41101 gcgaaatcaa cggcggcgta ctgaccatta cctttgagaa tggcagcaaa atcattatca
    41161 accgccagga gccgctgcac caggtatggc tggcaaccaa acagggcggc taccattttg
    41221 acctgaaagg cgatgagtgg atttgtgatc gcagcggcga aaccttctgg gatttgctgg
    41281 aacaggcggc gacgcagcag gcgggtgaaa cagtcagttt ccgctaagat tgcatgccgg
    41341 ataagcctcg ctttccggca cgttcatcac gaaaaatatt gctgtaatag cggcgtatcg
    41401 tgatcctgat tggcaggcgg catgttaccg atagattttg tgcggaacgg aatcacctgt
    41461 tcacgaccat caaccttcac aatctgatag aactgcggca ggttgaagtt gatgaagctt
    41521 gagccgtagg taaaacggtc atgcgatgac gagtagaagc gactgacgtc acgtaccagc
    41581 tcctctttgc tgccttcgca gtggtgatat acctcaaccc ggttgctttc gtcgagaatg
    41641 tagatattaa agccattctc gtcttgcgtt tcttcgaaaa agaactggat gatcccttcg
    41701 ctggcaaagc cgtccaccac cgccggtaat ttgacgtgat tggtttcaac ctgcactgac
    41761 aggccgtgca gtttgttatg cgaaatcgcg ccataaaact cgatggcgtt ttccagtttc
    41821 tgtaccgata cattcaggcg ttcgaagaac aacccccagg tttgaccaga aacgcgcagc
    41881 gccttgaaac gcccggtttc ctggcgggtg ctggaaagac gcaattcaat acactcagaa
    41941 accagttgct gcacgcgagt acgaattaag ccgcgcagat gctggctata acagaagact
    42001 tccacgctat ctggcggtgc ggcgtcctga tgcattttgc cgagaatagt tttcagggct
    42061 tcgatcatcg attgctcgcc gttgaagtgc agcgtacgca cttcgttcca cgagttgcgg
    42121 tacagcaggt caacgctacc taccaggcaa ttttgattct cgccaaagct gaagacatcc
    42181 agcttacgga aatcgaaatg caccacctga ttgcggaacg ccgctgtcgg gtcatattcc
    42241 aggttaacga taatcgccag atggcggatc tcacacgggc tgtagagcgc cttcggtgtc
    42301 ggtgcaggta agcgcagcgg gaaatggtgc gacacgtcgg cgaccatctc ctgcaactta
    42361 ggcaaatcga caatgccgtt acctttaata tacaaacggg tgcgcgaggt cagcaggccg
    42421 ttaaaccatg cccacgccac cagtttattc aggtaacggt tatattccag cggctgatgg
    42481 ctgatgatcg actcaatatt tggcgcgcgg ttatacagat accaacctga acggttagcc
    42541 cggcccggcg gcacataaat aaaggtcaga ttcggttccg agagatcggg tgaaatctgc
    42601 gggtttacca gcgtcacttt acctggtaat gcttcaaacg cggcatacag cttacgcgtc
    42661 agcacgccga tatcctgcgg actggcggag acgctaaggt tattgcgacg cgcaaagcgg
    42721 atcagattac ggtagctctg catcatcgcg tcgagcaact cgttgtgcgc ctcacgcacc
    42781 tgatcaatct tccagttagc gcggttatcg agcattgcca gacgagcttc gtcccaaccc
    42841 cactcgctca ctaactggct caacactgcg cgacgccagc ctacgcaggc gcgttcacgg
    42901 ctgagctttt cgcacacttt taaatagaag cagcgacgta ctaaatccag acgggtaaaa
    42961 tcttcaatcg ccgtcaggta ttcagtaaca cgctccagca tcatgcagta tggatcgaga
    43021 ccaaacgata caatctcgcc gtcgtgcaaa cgctgtttga tatctttcgc cagcagacgt
    43081 gggttcgggt attcccagga ataggcttcc agcagcagtg ttttcagtac cgctttgtat
    43141 ggggaatcga tactcttgta gagctgccaa aggctggcac caaagtactc ttcagcagaa
    43201 agcgagctta agccaccgag atccagccat tcatttggcg tcagcacgcc ctgcgcgtaa
    43261 agcgtcatca catagtcgtc gtaatgctct tcttcgtcgc acggcaccat attccacaga
    43321 atacgcttac cggcgagacg cacggcggta cgataaaatt cgtcaagcag cagtatatgc
    43381 tgggtggagc cacaatcttc gccccccagg ctgccgcttt cattatgacg gaagcggttt
    43441 tcatcaatca ggaagaagct gacttccaca cccagcgagg cggcccagtt ttccagcagg
    43501 ctacatttac gttgtagcaa ttggcgctct tcgctatcga gccaggattg atgacagacc
    43561 cagatatcca ggtcagagga acaactttgc cctacggacg aggtgctgcc catggtgtat
    43621 acaccagtaa ttggaagctc acctttcggc ggatcctgta ctgacattcc acgatacagt
    43681 tcaagctcgt tcaggtagtg gcgttgagtt tcatcaggcg tgtaaaggca aatgcctttg
    43741 ggaacgttac catcaaggta acccggcatt agcggatggt gatagtgcaa caatgtcggc
    43801 agtagactgt agacctgttg gaatgcaggc cccatagcag caagcgcgcg atccacacgc
    43861 aattgattta tggcatccag tctctgtttc agagtctcaa tatagaggta caagacgtat
    43921 cgcctgattt gctacccgtc atgactgtga ttccgccaac atcaacggta acacgcggca
    43981 ttcgggatat ttcgtatgtc aaaggtaacc gttaccactt ttcgcgcctg gtttttttag
    44041 tttcacgacg aaaaaatggt ctaaaacgtg atcaatttaa caccttgctg attgaccgta
    44101 aagaaagatg cgctacatac aagtgtagca ccgtttattc tctgtaaatt ccttattaca
    44161 acggcgtgaa acgcctgtca ggatccactg ccagacctca ttttacggtt tgcgcaggcg
    44221 tctacgtttc accacaacac tgacatcact ctggcaagga tgttaggatg gaccacggat
    44281 gataatgacg gtaacaagca tgttagacaa tgttttaaga attgccacac gccaaagccc
    44341 acttgcactc tggcaggcac actatgtcaa agacaagttg atggcgagcc atccgggcct
    44401 ggtcgttgaa ctggtaccga tggtgacgcg cggcgatgtg attcttgata cgccgctggc
    44461 gaaagtaggc ggaaaaggct tatttgtaaa agagctggaa gtcgcgctcc tcgaaaatcg
    44521 cgccgatatc gccgtacact caatgaaaga tgtgccggtt gaattcccgc aaggtctggg
    44581 actggtcact atttgtgagc gtgaagatcc tcgcgatgcc tttgtgtcca ataactatga
    44641 cagtctggat gcgttaccgg caggcagtat cgtcgggacg tccagtttac gtcgccagtg
    44701 ccaactggct gaacgccgtc cggatctgat tatccgctcc ctgcgcggca acgtcggcac
    44761 tcgcctgagc aaactggata acggcgaata cgatgccatc attcttgccg tagccggact
    44821 aaaacgttta ggtctggagt cacgtattcg cgccgcgttg ccacccgaga tttctcttcc
    44881 ggcggtagga caaggtgcgg tgggtattga atgccgcctt gatgattcac gcactcgcga
    44941 gctgcttgcc gcgctgaatc accacgaaac tgcactgcgc gttaccgcag aacgcgccat
    45001 gaatacccgt ctcgaaggcg gatgtcaggt gccaattggt agctacgccg agcttattga
    45061 tggcgaaatc tggctgcgtg cgctggtcgg cgcgccggac ggttcgcaga ttattcgcgg
    45121 tgaacgccgc ggtgcgccgc aagatgccga acaaatgggg atttcgctgg cagaagagct
    45181 actgaataac ggcgcgcgcg agatcctcgc tgaagtctat aacggagacg ccccggcatg
    45241 agtatccttg tcacccgccc gtctcccgct ggagaagagt tagtgagccg tctgcgcaca
    45301 ctggggcagg tggcctggca ttttccgctg attgagtttt ctccgggtca acaattaccg
    45361 caacttgctg atcaactggc agcgctgggg gagagcgatc tgttgtttgc cctctcgcaa
    45421 cacgcggttg cttttgccca atcacagctg catcagcaag atcgtaaatg gccccgacta
    45481 cctgattatt tcgccattgg acgcaccacc gcactggcac tacataccgt aagcggacag
    45541 aagattctct acccgcagga tcgggaaatc agcgaagtct tgctacaatt acctgaatta
    45601 caaaatattg cgggcaaacg tgcgctgata ttacgtggca atggtggtcg tgagctaatt
    45661 ggggataccc tgacggcgcg cggtgctgag gtcacttttt gtgaatgtta tcaacgatgc
    45721 gcaatccatt acgatggtgc agaagaagcg atgcgctggc aagcccgcga ggtgacgatg
    45781 gtcgttgtta ccagcggtga aatgttgcag caactctggt cgctgatccc acaatggtat
    45841 cgtgagcact ggttactaca ctgtcgacta ttggtcgtca gtgagcgttt ggcgaaactc
    45901 gcccgggaac tgggctggca agacattaag gtcgccgata acgctgacaa cgatgcgctt
    45961 ttacgggcat tacaataact ctcataacag gaagccataa tgacggaaca agaaaaaacc
    46021 tccgccgtgg ttgaagagac cagggaggcc gtggacacca cgtcacaacc tgtcgcaaca
    46081 gaaaaaaaga gtaagaacaa taccgcattg attctcagcg cggtggctat cgctattgct
    46141 ctggcggcgg gcatcggttt gtatggctgg ggtaaacaac aggccgtcaa tcagaccgcc
    46201 accagcgatg ccctggctaa ccaactgacg gcattgcaaa aagcccagga gagccaaaaa
    46261 gccgagctgg aaggcattat taagcaacaa gctgcacaac ttaagcaggc gaatcgtcag
    46321 caagaaacgc tggcaaaaca gttggatgaa gtccaacaaa aggtcgccac catttccggc
    46381 agcgatgcta aaacctggct gctggctcag gccgattttc tggtgaaact cgccggacgg
    46441 aagctgtgga gcgatcagga cgtcacgacc gctgcagcgt tgctgaaaag tgcagacgcc
    46501 agcctggcgg atatgaatga cccgagtctg attaccgttc gtcgggcaat taccgatgat
    46561 atcgccagcc tttctgcagt atcgcaggtg gattatgacg gcatcatcct taagcttaat
    46621 cagctttcaa atcaggtaga taacctgcgt ctagccgata atgacagcga tggttcgccg
    46681 atggattcag acggtgaaga gctttccagt tccatcagcg aatggcgtat caatctgcaa
    46741 aaaagctggc agaactttat ggacaacttc attacgattc gccgtcgtga tgacaccgcc
    46801 gtaccgctgt tagcgccaaa tcaggatatc tatctgcgcg aaaatattcg ctctcgcctg
    46861 ctggtcgcag cacaagctgt accgcgtcac caggaagaga cttatcgcca ggcgctggag
    46921 aacgtctcca cctgggtacg tgcttactac gatactgatg atgccaccac caaagcgttc
    46981 ctcgacgagg tggaccagtt aagccagcaa aatatctcga tggatcttcc ggaaaccctg
    47041 caaagccagg cgatgctgga aaaactgatg cagactcgcg tgcgtaacct gctggcacaa
    47101 ccggcagcgg ggacaacgga agctaaacct gcacctgcac cgcaagctga tactccggca
    47161 gccgcgccgc aaggagaata accatgctaa aagtgttatt gctctttgtg ttgctgattg
    47221 cggggatcgt ggttggcccg atgattgccg gccatcaggg ttatgtgctg atccagaccg
    47281 acaactacaa tatcgaaacc agcgtcacgg gcctggcgat catattgatt ctggcgatgg
    47341 tagtgctgtt tgccattgag tggctactgc ggcggatctt ccgcactggc gcgcacaccc
    47401 gtgggtggtt tgtcggacgt aagcgtcgcc gtgcacgtaa gcagaccgaa caggcgctgc
    47461 tgaaactggc ggaaggcgat tatcagcaag ttgaaaagct gatggcgaaa aatgccgatc
    47521 acgcggaaca accggtggtg aactatctac tggctgccga agccgcgcaa caacgtggtg
    47581 atgaagcacg cgccaaccaa catctggaac gcgcagcgga gctggccggc aacgacacca
    47641 ttccggtaga aatcacccgc gtacgtctgc aactggcccg taatgaaaac catgctgcac
    47701 gccacggcgt ggataagctg ctggaagtta cgccacgcca tccggaagta ttacgtctgg
    47761 cggaacaggc gtatatccgc acaggtgcat ggagttcgct gctggatatt atcccatcaa
    47821 tggcgaaagc ccatgttggt gatgaagaac atcgtgcaat gctggaacaa caggcatgga
    47881 ttggcctgat ggatcaggcg cgtgccgata acggtagcga aggtttgcgt aactggtgga
    47941 aaaaccaaag ccggaaaacg cgtcatcagg tagcgttgca ggtggcaatg gcggaacatc
    48001 ttattgaatg tgacgatcat gatactgccc agcaaattat catcgatggc ctgaaacgcc
    48061 agtacgacga tcgcctactg ctgccgattc ctcgactgaa aacaaacaat ccggaacagc
    48121 tggaaaaagt gctgcgccag caaatcaaaa acgtcggcga tcgcccgctg ttgtggagca
    48181 cactgggcca gtcactgatg aagcacggag aatggcagga agcatcgctc gccttccgcg
    48241 cagcgctgaa acaacgtccg gacgcctacg attacgcatg gcttgccgac gcgctggaca
    48301 gactgcacaa gccggaagaa gctgcagcga tgcgtcgcga cggtttgatg ttaacgttgc
    48361 agaataaccc gccacagtag ttccttctca cccggaggca agcacctccg gggccttcct
    48421 gatacataaa aaaacgcctg ctcttattac ggagcaggcg ttaaaacagg tctgtatgac
    48481 aacaagtggg tgcttcactc aacgttgtgt ccatggtgtc tgatgaggca taagcgacat
    48541 ctgtcagtgg acgataagca ccgtaaacgg ctctgcgtca ttccggagtt tatgaggcac
    48601 taaggcgaac ataagagatg gaatgagcat ctactcgttt attatgccac agagaatcgg
    48661 gaaataacat cccttaacac ttgttatgag ataattctgt aatcctcttt gcttcctgag
    48721 taataacttc ctgagtgaat atttaacctg agcttgatcc tacacatact tattatgaat
    48781 gataaaattc attcaattaa taacacatat attaattgcc gttaaaacta aaaacagcat
    48841 caataatcaa cgcgatataa taaacctgcc ttacatatca actgcgccag aggtaggatt
    48901 gaaaacgctc tcctgatttt ccaattcatt ttctggataa ataaataatt tatttttgtc
    48961 actattattt atgtaatcat cctgtcaggg agagggatct caattatcaa tgcttaatta
    49021 cgtcatcatt ttgatgacat gaaaccggag cattttgcat ggaattttcg ttttcaccca
    49081 aacgtcttgt tgttgctgtc gccgccgctc ttcctctcat ggccagcgca gcagataccc
    49141 cgtcaactgc caccgcacgc aaaggctttg ccggatacga tcacccaaac cagtatctgg
    49201 ttaaaccggc gaccactatt gccgacaata tgatgccagt aatgcagcat ccggcgcagg
    49261 ataaagaaac ccagcagaag ctggcagaac ttgagaaaaa aaccggtaag aaaccgaatg
    49321 tggttgtttt cttgctggac gatgtgggct ggatggacgt cggttttaac ggtggcggcg
    49381 tggcggtggg taaccctaca ccagatatcg acgccgttgc cagccagggg ctgattttaa
    49441 cttcggcgta ttctcaacca agctcttccc caacccgcgc caccattctc accggacaat
    49501 actccatcca ccacggcatt ctgatgccgc caatgtacgg gcaaccgggc gggctgcaag
    49561 ggttaaccac gctgccgcag ttgctgcacg atcagggcta cgtcactcag gccatcggaa
    49621 aatggcatat gggggaaaac aaagagtcgc agccgcagaa cgttggcttt gatgatttcc
    49681 gtggctttaa ctcggtgtct gatatgtaca ccgaatggcg cgacgttcac gtcaatccgg
    49741 aagtggccct gagtccggac cgttctgaat acatcaagca attaccgttc agcaaagatg
    49801 acgttcatgc ggtgcgcggc ggcgaacaac aggccattgc cgacattacg ccgaaatata
    49861 tggaagatct ggatcaacgc tggatggact atggcgttaa gttcctcgac aagatggcga
    49921 agagcgataa accattcttc ctctactacg gcactcgtgg ctgccacttc gataactacc
    49981 caaatgcgaa atatgcgggt agctctccgg cacgcacctc gtatggcgac tgcatggtgg
    50041 agatgaacga tgtgttcgct aatctgtata aaacactgga gaaaaacggt cagcttgata
    50101 acacgctgat cgtctttacc tccgataacg gaccggaagc cgaagtaccg ccgcacggac
    50161 gcaccccgtt ccgtggtgcg aaaggttcga cctgggaagg cggcgttcgc gtaccgactt
    50221 tcgtttactg gaaagggatg atccaaccgc gtaaatctga cggtattgtc gatctggcag
    50281 atctcttccc taccgcgctg gatctggcag ggcatcctgg agcgaaagtg gcgaatttag
    50341 tgccgaaaac cacctttatc gatggtgtgg accagacatc cttcttcctg ggaacaaatg
    50401 gtcagtctaa ccgtaaggcc gagcactact tcctcaacgg taaactcgct gctgtgcgta
    50461 tggatgagtt caagtatcac gtcctgattc agcaacctta cgcttatacc cagagcggat
    50521 atcagggtgg attcaccggc acagtaatgc aaacggcggg atcgtcggtg tttaacctct
    50581 acaccgatcc gcaggaaagc gactccatcg gcgtgcgcca tattccgatg ggtgtaccgc
    50641 tacagaccga aatgcacgcg tatatggaga tcctgaaaaa atatccacca cgcgcgcaga
    50701 ttaaatctga ctaagccggc gctatcgctg agatctgcct ttgccggatg cgatgctgac
    50761 gcatcttatc cagcctacag aacgctgcaa tttattgaat ttgcacgatc atgtaggccg
    50821 gataaggcgt ttacgccgca tccggcaatc aaccgcaggc ggccgccgat ttctacttac
    50881 tcaccaccag caaatgcgca tgcataatgt cgctggccgg gcgaccgtgc gccagcaaat
    50941 cagccattgc tttaagatat ggcggtagat ggcggaaata acgctgatac ccggcacaca
    51001 aataattcag tcccggtttg ccgctggcat cgagcatgaa gcggtgtttc gggcagcctc
    51061 cccagcacgc ttttaacacg ttacaactgc gacactgcgc cggtaactgc ttaaatttat
    51121 cttcaccaaa cgcctgctgt tgcggggaat cgatcatttc tgcaattgtt tgctggtgca
    51181 tattccccag ccgatattgc ggataaacat agtgatcaca ggcgtaaacg tcgccgttgt
    51241 gctcaacaat caccgagcgc ccacaggttg gctgatgatg gcaaaccgca cccggcgcac
    51301 cgacaaaatt ggcaaacgcc cattcgatat tcatcacgaa aatcttgccg acgtcgcgtt
    51361 tgatccagtg gtcgaatatc gccaccagaa actcaccgaa ctcctcgggg cgcaccgacc
    51421 attccgttag ctcaccctga atatcaccag gcgcatgtaa cttaagtcca tcgcgggcag
    51481 ttgtttcatc agccaggcgc tcgaccaccg gaataaactg gatgaattcg actcccgcat
    51541 cgcacaaaaa atcatatacc tgcaacggtt gctgcgcgct ggtgcgatta acgcagacca
    51601 gcacgttata gtcgacatga tgtttttgca ggagcgtcag ggcacgcatc accagcttat
    51661 gcgtgggtct gccaccttta gtcacgcgat attgattgtg gatctcaggc gggccatcca
    51721 gcgataaacc aacaagaaaa tgatgctccg cgagaaacgc gcaccattcg tcatccagca
    51781 gcacgccgtt agtctggaag ctgttactta tcttcctgcc agcaccatat ttcgcctgta
    51841 gcgctacggc acggcggtaa aacgccagcc cgagtagcgt tggttcgccg ccctgccagg
    51901 taaaagccac ttcgttttgc ggttcgctgg cagcgatata gtgacggaca tacgcttcca
    51961 gcgtgtcatc gtccatatgc gtgactggct tttcgcggta aagggattgt ttttcgagat
    52021 aaaaacagta gtcacagttc agattacaat cggaaccgct cggtttcgcc atcacatgaa
    52081 aagcacgcgt tggaacctgt tgcagcatgg tcgctccttg cctgaagtca tccttcaata
    52141 cgttaagggc gaaatcatac cgtggggcaa tgagttatta cgggcgttta ttgcgaaggg
    52201 agggtgacga aatgcacaga aaacaaaaaa ccccgccgaa gcggggttca aaattggtcg
    52261 gcgagagagg attcgaacct ccgacccact ggtcccaaac cagttgcgct accaagctgc
    52321 gctactcgcc gaaatactgc tttttgaatt tttagttcaa ttctttaaag tcgtggtgcg
    52381 agggggggga cttgaacccc cacgtccgta aggacactaa cacctgaagc tagcgcgtct
    52441 accaattccg ccaccttcgc attgtcacaa cttctaataa tggggtggct aatgggattc
    52501 gaacccacga caactggaat cacaatccag ggctctacca actgagctat agccaccact
    52561 acaaatcttg ttacgcggta ttactaccac cgcagctcaa gcgccgggac taaatggcgc
    52621 gcccgacagg attcgaacct gagacctctg cctccggagg gcagcgctct atccagctga
    52681 gctacgggcg cttagcgccg ttgcgggggt ggataatacg gacttcccac ccctctgtct
    52741 agtccctttt taaataaatt gcgcgtttgg ttacggtttg tgcgttttgc tgcttattcc
    52801 tccagtttat gcgctttccc gtggcgatta aggccaaaaa ctttataaat cgccgtcacc
    52861 gccagcataa agatgatgcc aacaaacagc gacatacgcg tatcttcatt aaagtacatg
    52921 ccgatcaaaa cgcaaatcag gaatgccatt gttacgtaat tggcccacgg gaacaggatt
    52981 gagcggaacg gatggctggc aatcgccgct ttatgtgcac gccgaaaacg cagctggctt
    53041 atcaatatca caaaccatgg caccatcccc ggaagcacgc tggcactgta gacgtagaca
    53101 aacacacgct gcggattggg aatgatgtag ttcaggcatg agccaattag cagaatagca
    53161 atagatactg ccacacccgc aaccggtacg ccgtgacggg aaactttcgc cattgccgcc
    53221 ggtaactgac ggtttttcgc cagtgcgtag agcatacgtc cgcaactgta catgccgctg
    53281 ttacagccag agagcgcagc cgtcagcacc acaaagttga taatgcccgc cgctgcggta
    53341 ataccgattt tggcaaaagt cagtacgaac gggctgccgt tgctgcctat ttcattccac
    53401 gggaagatgg tgacgataac gaaaatcgcg cctacgtaga aaatcaggat ccgccacagc
    53461 accttgccta cggcactgcg cagcgtcacc tgcggattct tcgcttcacc ggcagtaatg
    53521 ccaatcagct ccacgccctg gtaggacgcc accacaatac acagagcggt caggaaccct
    53581 ttccagccac ccgcaaagaa accgccatgc tctgtgagat tgctaaaacc aatcgactgc
    53641 ccgccattgc caaagccaaa gaaaatcacg cccaggccaa tgacaatcat cacgataatc
    53701 gtggtgactt tgatcatcgc gaaccagaac tcgatttcgc cgtacaaccg caccgccgcc
    53761 agattcgcca acgccaccag cgccactgcg atcaatgcgg gtatccactg cgccatctcc
    53821 gggaaccaga actggacata aacgccaatg gcggtgattt cagagatccc caccgccatc
    53881 cacataaacc agtaagacca ggcggtgaga tagccaaaga acgggctcat ataacgatgc
    53941 gcataaacgg cgaacgaacc ggtaaccggt tcgaggaaca acatttcgcc cattgaacgc
    54001 atgatgaaaa agacgaacag cccggcgatg atataggcca acaatacgga tggcccggcc
    54061 catttcaggg tactggcggc ccccataaac aggccgacgc caatggtgcc ccccagggcg
    54121 atgagttcga tatgtcgagc ttccagccca cgctgtagct ctggtttgtt atctgccata
    54181 aatcctcgtg ttgtgtttgc atgctttccg gtgttaccgg ttatcgttat gggtacatcg
    54241 agtgttgcaa atgttttcgt aattcaggag aaatggcaaa taaagcatta aaaatttgaa
    54301 tgctttgtgt aataaaaaag cagacaggcg acggagtgac cactccgtcg ctttacaaag
    54361 agaggaaaat cataggttgc cggtgtagtg ccagcgtaaa taacgcagca aacgaagctg
    54421 acgcttaatg cggctcggct gcgaaagcag gcggtagagc cactccagcc ccagcgtttg
    54481 ccagattttc ggtgcgcgtt ttacgtgacc ggtgaaaaca tcgtaagtcc cgccaacgcc
    54541 catatacagc gcatctggat gtaccagacg gcagtcgcgc atgatgatct cctgctttgg
    54601 cgatcccatc gcaacggtga cgatttgcgc accgctggca tgaatgcgtt caaacagcgc
    54661 ctgacgctgc tcgggtttaa aataaccatc ctgactgcca acgatattca cattccactg
    54721 gttgcgcagt ttagcttcag tttgcgccag cacttcaggt ttaccgccca caagaaatac
    54781 cggcgtccct tctttgcctg cgcgcgccat cagctcttcc cagagatcgg caccggcaac
    54841 gcgggaaacc tgcgcctgcg ggtacttttt acgtactgaa cgtacaacgc tgatgccatc
    54901 cgcatattta aattcggcag cgttaattaa ctccctgacc tcggcgttat cttcaatagt
    54961 cagcattttt tcagcattaa tggcaaccag cgttccctgc ttaagctgcc cgtcagcaaa
    55021 cagataatcg agggcgtgct gcatatcacg ccaaccaatc aactgtaagc cacgcagcgt
    55081 ataggttggt gccgtggtgt tgttattcat tgttatcctt caacctgcgt ccggagcgat
    55141 gattttgtac gtttatgaat gagtccggcg ctttcaaaaa gccagtacaa cagttttgcg
    55201 atcatcagac atgcgccgaa gaccacgata aaaaagacca cgcgtgagac aaacgaatcc
    55261 agcccttcac gcgccagcac gatcatattg aagatcgccc caaagcagaa actgtgcaat
    55321 atcgcagctt tatagcgatt aggctcgcgg ttgcccagct catacagcca gtcgaaccat
    55381 ttgatgatca gaccaaccac gatcgccccg agcgggatga acaacgcgcc gcccatcacc
    55441 accagtgagc ctataagcgt aggcgagatc gccagtccgg agtggttatt cagcacttcc
    55501 caggtaaagt agttggctga gttcagcacc atactcgggc gacccggcca cagccaggaa
    55561 gggataaaga catagaaatc gcggacaatt ggagccaggc cctggaagtc gatgttgtcg
    55621 tagttctgca acagcaacgc cagattctcc cacggcgaga aggtgtcgcg agtgagatag
    55681 agaaacgtat agaacgcttc atcgccgctc acattcattc catagcgttt tagtgccagc
    55741 cagaacatgc caacaatccc cagcacgccc gccgccgcca gcatccacaa cgaaatccag
    55801 ccgcgaataa tgccaataaa caggaagata gcgaatgcga tgatgatatt ggcgcgagtg
    55861 ccgccgacaa tcatataagt cagcaagcca aaggcgaccg tgctgacgag gaaaaacagc
    55921 cacgctttgc tgtcctggcg cagaaagtag accaccagca tcgccgggat gaaaaagtaa
    55981 aagaagcgtt ttaacgccac gccggagact tcactggaaa agatctgact gtaggagtta
    56041 agccggaaca gcaaaaagcc gttgtgcatg aagaagatgc cgacgcttac cagcgcgata
    56101 cccatcagga tcacccacgt aagattggtc tccacgcggt tcatggtaaa cagcggacgg
    56161 cgcggtacat cagcaacgcg tttgcgtagg cgggttttgt aggtgacata gtaaaccgcg
    56221 tagaagcagc ccgcagaaag caacgcctgc aacaagattt ctggcggcgc gacaccaaca
    56281 tcaaagcgaa ataccagcac gctggtcagc gggaagccga agaaaaaggt gagcaaaaac
    56341 agcaatgaaa agaagacatt gaagttaaag cgcacacggc gaaactcaaa ccaggtcagc
    56401 gtggcaataa acagcgtgca gagcagccag acaacaaaca ggccactgaa ttgcagcaga
    56461 ctcatgcgac ctccccggcg gcaatcgcca acgcccgctg ccagccttgt agatagttag
    56521 ggctaaagaa ggcaatggtg tttttatcca ccgacgccaa ctggcgctgc gcttcacgca
    56581 caatatcctc gttgagatcg tcggtagtaa acagcaccgg caaatgttgt tccgtcatat
    56641 cctgccagaa cggattttcc cggttaagca cacaaggaat gcccgcctga atcagtaagc
    56701 acagcgtacc aatgccctgc tggcgggcaa aaataaagta accaagatcg cactgacgaa
    56761 gtagcgccag ataggcgtca aattccagtt tttcgctcag aatttgtaga ttttcttcgc
    56821 tgaataactc cagccccgcc tgacgaactt cctcaatgta cgcttcgtta ttaggcggat
    56881 atcccatcgg caccaccact tttaccgtat cgccaaattg ctgatgaacg gcgcgcaagg
    56941 cagcaatatg ctcattgctg cggtcgccgg agttccccac cagaatggtc attttccctt
    57001 cacgttgccg atcgttcgcc atcgtattga gcgaagggtc catccgcgtc gggaagaaca
    57061 gcagttcgcc ccgcaccttt gggtgcgttt tggcaaaaaa gctcaaatcg ccgcgggtgg
    57121 caaatacaca gccgactcgc ttttgcgcca ggcgacgtag tgggtaaaaa agcttatatc
    57181 tcaagccact ggaaagctca tacaggtctg ccccccagat atgccagaaa aactggctgg
    57241 gcttaatgcc accactcagc agagccagcc acagtgtggg attgaactga ccgtggaaga
    57301 aaaaacgctg ctgacggtta gcttttgctt tcgcgatgac cgcttccgcc agcgattttt
    57361 tcccagggaa aaattgcaca gaaagcgccg gacagctatc acttaagccg tcgtccttgc
    57421 caacaaccat aaactcgcgc gcgtgctcgc tcgtcgcggc cagcgcgtca ttgaaaaacc
    57481 gcaaaacggt tcggttatgg tgagggatat ccgatcccag tacgtgaatc agtacagtca
    57541 tgcccgccta cgccagagta aaaacacgcc acaacaaaga gaaaaataga cgatataagt
    57601 tgccatatat gcctgcgccg cgcccagtgc accatgcgca gggattagcc agtgggcaaa
    57661 taccatcaat aaagtgaact ggctgacttc cgccagaata taaaaccgca gtgacgcttt
    57721 ggcgatcacc agataaccaa agacataagc gcccactttt aacacatcac ccactaactg
    57781 ccaggcaaag agatcgcgca tagcggtaaa tttattcgac aacagcagcc agatagcaaa
    57841 atcacgcagc agccagacgg taaaactcgc cgccgccact gccggtaaga cgaatttcag
    57901 cgatttaacc acttcccggg tgatatcgcg cttttccgtt agccgcgaca acgtgggcag
    57961 caaatatacg ctgaacgatg ccgtaataaa ttgcaggtag gcatcggaaa tactgctcac
    58021 cccttgccag atccccacct catcccagct atactgcgcc gccagcagtt tacgcatcat
    58081 gatgtaagca acaggcaagg tcaccgacgt aatcaacgcc atgagcgtaa atttgctcaa
    58141 ctgccctgcc agaccgttat cccagctggg tttcagatag cttaacggga tgacaccacg
    58201 tttgatcaac atgatggcgg caggaattac caccagcgcg ggaatcagcg ccagacccag
    58261 caacgcccct tcataaccgc ccaaacggta actgacgtag tacgcgagaa cgccaatcaa
    58321 gctgccgaca atcagcgata acgcattacc tgcggcatcg cgaaagcctt tcatcagcgc
    58381 cagtaacagg ttgccccagg cgatccccat ttgcaccagc gccactaaac gcaccagccc
    58441 ctgatagtcg gtattaccaa acaatccctg gctgattggc gcagctgcca gcacaaaaac
    58501 cagcgccatc agcgtagaga aaccaagtac catcgctgat gaagtgccga ccacgcggcg
    58561 cagctgttgc ggattatcat ggtactgggc aacgtatttg gttacaccgt taaagatgcc
    58621 agccccggca agcacgccga gcacggtaat caactggcgg aaatttgccg ccagcccaag
    58681 ccccgccgga ccaaatgaca ccgccagcaa cttaccgacc agtaacccgg caccaatctt
    58741 gaccagtgta ctggccgccg tccacaagga cgcttttgcc aacgacatat caggaaaagt
    58801 agttcaacaa agtcgcaatt accgtacgct gattgacggg cgacaggttg tagaacagcg
    58861 gcaggcgcag caggcgctcg ctctctttgg tggtgtagcg atcttcaccg tggaactcac
    58921 caaagtgttc ccccgcaggg caaccgtgca gcggaatgta atgaaacacc gccatgattt
    58981 ccgcttcttt cagaaagtta atcaacgcgc tccggtcatc aatatcccgc agtttaatgt
    59041 agaacatatg cgcgttctgc acgcagccat cgggaatcga cggcagctcg atacgcccgg
    59101 ctttcgccag aggcgctaac gcatcgtagt agttttgcca cagcgccaga cgttgctggt
    59161 tgatacgatc cgctgcttcc agttgcgccc acaggtatgc agcttgcaga tcggacatca
    59221 aatagctgga gccaatatcg cgccaggtat atttatcgac ctgaccacgg aagaactggc
    59281 tgcggttagt gcccttttca cggatgatct cggctcgttc gattaacgct ttatcgttaa
    59341 tcagcgtcgc gccgccttca ccgcccgccg tgtagttttt ggtttcatgg aagctaaagc
    59401 agccaatatg accaatggtt cccagtgcac gccctttgta agtggacatc acgccctgag
    59461 cggcatcttc taccacaaac aaattatgct ttttcgccaa cgccataatg gtgtccattt
    59521 cgcaggccac acccgcgtaa tggaccggca cgataacgcg cgttttgtcg gtgatcgccg
    59581 cttcaatcag cgtttcgtcg atgttcatgg tgtccgggcg aacatccaca aaaacgattt
    59641 ttgcgccacg cagcacaaag gcattggcgg tggagacaaa ggtgtagctc ggcatgatca
    59701 cttcatcgcc aggctggata tcgagcagca gcgccgccat ctccagcgaa gcggtgcagg
    59761 acggcgtcag taacactttg gcgctgccaa aacgttgctc cagccactgc tggcagcgac
    59821 gggtaaaacc gccatcgcca cacagtttgc cgctacccat tgccgactgc atatagtcga
    59881 gttcggttcc caccaccggc ggtgcgttaa atggaatcat gtgatcacct gtataaccag
    59941 tacgcggtgc tttctacatt cgcaccactt tgtatgtatc gtttaagcgc ggcggtgttg
    60001 cccatttggg tcgccacccg caaagttgtt ttaccgcgag catacgccca gtttagcgcc
    60061 gtttgcatca gctcagcacc tgcaccgcgt ccagccagca ggccaattcg cgcatctgtc
    60121 gcattgagtt cccgtaaaga gacatagccg cgaatatcgc cggacgccgc acgtaaaatc
    60181 agacattgat gatcaaaggt gccgcgcacg gcattttcaa tccactgtgc ataaaagcga
    60241 ctgctggcgt caggcgcata ccacggcgca cgaaaacggc tttgcgcaaa tgcggcgctg
    60301 gctaactgac gtaatgcggg aatatcggtc tcttgtgcca ctacagcacc gctatcactg
    60361 gcattgttca cgggtagcgc caaatcaact tcaccttcta ccagggagaa tcccagctgt
    60421 tgcagggcat ccagttcacc cgtatttgat gccgcaattt tggcctgcac ccgtgaccac
    60481 ggcgctaacg cgtctggcgt caggagcggt gcttcagacg taatgcgcac gatggcgctg
    60541 ttaacaccaa agaaggcgtt ttcccaggtt agtggctcaa tactggcgcg gacgggcacg
    60601 aagtaactcc agcagatatt ggccgtagcc agttttcgct aatgaactgg cagcacgctt
    60661 cacaccctcg tcatcgagcc agccgttacg ccaggcaatc tcttccaggc aggcaatctt
    60721 aaagccctgg cgtttttcca ccgtctgtac aaaggtgctg gcttcaatca ggctgtcgtg
    60781 agtgccggta tccagccagg caaatccgcg cccgagcagt tcaacggtca ggttgcccgc
    60841 ctcgaggtac atctggttga tggaggtaat ctccagttca ccacgctccg acggcttcac
    60901 ctgctttgcg tactccacga ctttactgtc gtagaaataa agcccggtca ccgcccagtt
    60961 tgacttcggc tgttttggct tttcttccag cgagatagcg cggaaattgt cgtcaaactc
    61021 caccacgcca aagcgttccg ggtccatcac ctgatagcca aaaaccgtcg ccccttcggt
    61081 gcgcgccgca acatgacgca gcttcggact gaagccctga ccgaagaaga tgttatcgcc
    61141 cagcaccaga caagaaggtt caccattaag gaaggtttca ccgatgataa aggcctgcgc
    61201 cagaccgtcc gggctgggct gttcggcata ttccagctgg ataccgaact cactaccatc
    61261 gcccagcagg cgctggaaat aacctttatc ttccggcgta gtgatgatga gaatttcgcg
    61321 gataccggcc agcatcagca ccgacagcgg atagtaaatc attggcttat cgtaaatcgg
    61381 caacagttgc ttcgatacgc cgcgcgtaat cggatgcaat cgggtgccgg aaccgcccgc
    61441 caggataata cctttcatgt ttgcctccgc tgaaaattag cctttcagac ctaaacgctc
    61501 gccctgatag ctgccgtcct gcacctgctt ccaccagctt tcattagcca gataccactg
    61561 aaccgtttta cgcattccac tttcaaaggt ttcctgcggc agccagccaa gttcacgggc
    61621 aattttcgaa gcatcaatgg cataacgcag atcatgcccc ggacggtcag cgacaaaggt
    61681 gatcaggtca cgatagtgcg ccacgccgtg cggcttgttc ggagccagtt cttccagcag
    61741 ctcgcaaatg gtttccacaa catcgagatt cttacgctcg ttgtgaccac caatattata
    61801 ggtttcaccg actttcccgg tggtcgccac gcaatacagc gcgcgggcgt gatcttccac
    61861 atacagccag tcacggattt gctgcccgtt gccatatacc ggcagcgatt tacccgccag
    61921 cgcgttgagg atcatcagcg ggatcagttt ttccggaaag tggtaagggc cgtagttatt
    61981 cgagcagttg gtgataagcg tcggcagacc ataggtccgc agccaggcgc gcaccagatg
    62041 gtcgctgctg gcttttgacg cggaataagg gctgctcggc gcatacggcg tggtttcggt
    62101 gaagaaatca tccgtcgagt gcaggtcacc atatacttcg tcagtggaga tatgatgaaa
    62161 acggaacgct gattttttat cttccgtcag cgcattccag taagcccgcg ccgcttcaag
    62221 caatgtataa gtcccgacaa tgttggtttc aataaacgct gccgggccgt caatagaacg
    62281 gtcaacatgg ctttcggctg ccagatgcat gacacagtct ggctgatgct cagtgaatac
    62341 gcgtgccagt tctgcccgat cgcagatatc aactttctca aaggcaaagc gctcgctttg
    62401 cgcgaccggt gccagcgaca tcaggtttcc ggcgtaggtc agcttatcga ccactaccac
    62461 cgcgtcgctc gtttcgttga tgatataacg caccagcgcc gagccaataa acccggcacc
    62521 acctgttatc agaatttttc tcatcagcgc cagactcctt tggcatcgac gacatactgc
    62581 tgatggacat tgtcgccatt gataactttg aactgactat gatcgaccag catcaccagc
    62641 acgtctgccg ttgccagcgc ctcgtcaagc tgcgccagag tacaaagccc ggtcagtttt
    62701 ttcggcaact ggtggatgtt aggctcaaca accagagttt cgccgctatg ccactgggcg
    62761 atcagttcag cgatttccat cgccgggctt tcgcgcaggt catcaatatt cggtttaaac
    62821 gccagaccaa agcaggcgat tttcagttca ctggcgcgtt tatcggtagc cgccaggcaa
    62881 tcagccaccg ccgctttcac ctgatcgata acccagaacg gtttgtgatc gttcacttcg
    62941 cgcgcggtac ggataagccg cgcctgctgg gggttctgtg ccacgataaa ccacggatca
    63001 acagcaatgc agtgaccgcc cacgccaggg ccaggctgaa gaatattaac gcgagggtga
    63061 cgattcgcca ggcgaatcag ttcccagacg ttaatcccct gatcggcaca aatcagcgac
    63121 aattcattag caaaagcgat attcacatcg cggaagctgt tttcggtgag cttacacatt
    63181 tccgccgtcc gcgagttagt gacgacacac tcaccttcga ggaaaatttt gtacagttcg
    63241 ctggcgcggg ccgaacaaac cggcgtcata ccaccaatca cgcgatcgtt tttaatcagc
    63301 tcgaccatta cctgtcctgg taacacgcgt tccgggcagt aagcaatgtt gacgtccgcc
    63361 tgctcgccca cctgctgcgg gaaagtgaga tccggacgca tctctgctaa ccattctgcc
    63421 atcttctcgg ttgaccccac cggcgaggtg gattcaagga tcaccagcgc gccttttttc
    63481 agcactggcg caatggagcg agcagccgat tcaacgtagg tcatatctgg ctcatgatcg
    63541 cccttaaacg gcgtgggtac agcaatcagc caggcatccg cttcaactgg cgtcgtgctc
    63601 gctcgtaaaa aaccgccttc tacggcagtt tttactacac tcgccaaatc aggttcgacg
    63661 atatggattt cgccacgatt gatggtatca accgcatgtt ggttgatatc gacaccaatt
    63721 acctgttttt gccgtgaggc aaacgctgct gccgttggca gcccgatata acccagtccg
    63781 ataacagaaa tggtcgcaaa actcatagtg atatccgatt attttttaac gcttccagaa
    63841 tgcgagagca tgcctgacca tcaccatacg ggttatgggc gcggctcata gcttgatatt
    63901 cgttttcgtc ttttaaaaga cgcgtcactt cctcgacaat tcgctgctta tccgtgccta
    63961 ccagacgcac cgtacccgcc gtcaccgctt ccggacgctc agtggtatcg cgcatcacca
    64021 gcacaggttt ccccagcgaa ggcgcttctt cctgaatgcc gcctgagtcg gtcaaaatca
    64081 gccaggcgtg gttcatcagc cagacaaacg gtaaatactc ctggggatcg atcagaatga
    64141 catttttcac atgccccaga atgcgattga ccggctctct gacgttcggg ttgagatgca
    64201 ccggatagac aatctggatg tcctggtgcg tggtggcgat gtctgccagc gcgtggcaga
    64261 tttcttcaaa gccacgaccg aaactctcac gcctgtgacc ggtcaccaga atcatctttt
    64321 tatcggggtc gataaacggg taatttgccg ccagttctga acgcagcttg tcgctgctca
    64381 tcacctggtc acgcacccat aacagtgcat caatgactgt attaccggta atgaagattc
    64441 ggctatccgc aacgttttca cgcagcaagt tttgccggga agtttcggtt ggagagaagt
    64501 gatacatcgc cagatgcccg gtcaatgtac ggttagcctc ttccggccac ggcgaataga
    64561 gatcgcccgt gcgcagacca gcctcaacgt gaccaacagg aatacgctga taaaacgccg
    64621 ccaggctggt tgccagcgtc gtcgtcgtat cgccgtgaac cagcacgacg tctggtttga
    64681 actcggcaag aataggtttt agcccttcca gaatccgaca ggttatctct gtcaggccct
    64741 gtcctggctg cattatgttg agatcgtagt caggtacaat ggaaaagagt ttcagcacct
    64801 gatcgagcat ctcccgatgc tgcgcagtga cgcaaacttt agcctcaaaa aaaggatctt
    64861 ttgccaacgc atgcaccaac ggcgccatct tgatggcttc cgggcgcgta ccaaatacag
    64921 tcagtacttt cacatcgatt ctcttcgaat aagcggcgag cgcctttgcg ctcaccgcag
    64981 cagtgttgct atttcgagca acggcgggtt aatgcgacac cagccccgat cagccccccg
    65041 acaatgcccc acataatcat caggaaggca cgacgtgggc tatcgcgttt taccggttct
    65101 tccggcgtac gcaaatagcg ataggtctga aaacgcggat ccagggttgg accaacattc
    65161 agggtgttta acatggcccg attctgatca tagtcgagat caaaggccgg accgacggcc
    65221 tgtaaatttt ccagtcgagc ctgaagcatt ggacgcccaa gcaggaacat ttctgaatca
    65281 ggtaattcct cggcaggtac atctgtcgca ctgcgcgaaa tattatgctg ctcagcaatt
    65341 ttcagcgcct gctcaatgct gttcatccgg cggtcgtaga tggctttcgc cacctcttcc
    65401 tgacgcttca cctgagcttt catctggatg gtacgcgccg cccatgcgcc tttcagctca
    65461 tcattcagat ggctggctgc acgctggctg gcaaaagcaa catactgacg taacaggtta
    65521 ttagcgtcag gcgcggtttc ggcaataagc ttcacgctgt cattgaccgc gcgggtaaag
    65581 tctccgggga taaactggat gttgttaatc atttcatcca gcaacgccgc atcggctttg
    65641 ctgttgccca ccatccgctg tttgtaatag tcggtttgca gccagaactc tctgcgggta
    65701 tcccacgagg ccagttgcat aacaaactct ttataggctt cgtccatgac cgatggttgg
    65761 tcggcagaag ccatgtttga acggacatcc aggttacgca aaaattgctg ctgcgagtaa
    65821 tatcccccca gcatattcac cgttggacga tcggtaatcg ccgtcgagct ccactcctga
    65881 cgagcaaaaa acgtatacgc cagcgcgatt aacgcaaacg ccagccccat gccaataatc
    65941 catagcttcc cagcccacaa ggtacgaaac aacccacgaa tatccagttc attttcagcg
    66001 tcttcggccg gtttcccagg cattggttgt gtcatcacat cctcatttat ttggttaaat
    66061 tggggctgcc accacgattt ctacgcagtc tgcgttttac gcgcttaata aagcgagcaa
    66121 ctttccaggc acgcttaatg caatatccat agaggaagaa tgctagcaaa aagagcacca
    66181 gcatgaccca ctccgggaca aaatgagaat attctgccag cacgccaatg gaagcgagca
    66241 gtgctgcggc aagggtaatc agcacaaacg cctgacggga agtaaacccg gcacgcatga
    66301 tcaaatggtg aatatgctga cggtcaggag agaatgggct catgccttta cgcaggcgac
    66361 ggtacataat cgccaccata tccattagcg gaatggcgat tatccacaaa gcggtaaccg
    66421 ggctgatggg atgggttttg ccctgggtcg tttcgagcag gatccagata acggtaaaac
    66481 caatcagcgt actgcccgca tcacccataa agactttgta gcggcgaccc aggataccaa
    66541 ggttaagcat gatgtatggc aggatggcgg cgatcatcgc aaagcaccag attgcgaggc
    66601 tggtttgccc gtcgaaccac aaaatcatac cgattgctgc aaacgagacg caggacaacc
    66661 cgcccagcaa gccatcaatg ccatcaacca tgttgaacgc attaatggcc gcccagacgg
    66721 caaatagcgt caggaagtaa ccaaacggtc cgagcaccat ctcccaggag ccaaagatat
    66781 aacccaggct actgagataa agcttgccga acaccatcat aacaatgcca acagcggcct
    66841 gtatggtggc acggattttt acgctgatat caaaacggtc atccagcgcg ccaatgaaaa
    66901 caagcacacc ggcacaagcg agatagagag atgcatgcgg aatatagtaa tcgacaattc
    66961 cgaacgtgaa gcaaatccct gcgtaaaccg aaatcccccc aacgagaggt atcaatccct
    67021 ggtgacgttt gcggaagttt ggtttatcca ctaaaccgac tttttttgcc accttacggg
    67081 caaaaaacag aaacagtgtc gtgaataaaa aaatactgat gagatcagta ctcactgcca
    67141 gtaaattcac aatgcatgct ctcagagaaa attattagca gaagtataac cacgaagacc
    67201 tttattcaga agggaaagtc cgttccaaac ccaccagtcc tgtgcaaaaa ttaaccattt
    67261 gatatgcaaa ttgcataaca tgccagcaaa ttccaggaat tttcctaaca tcgccagcgc
    67321 ggcattaaga ttacagatat aaaagcaaaa cgccacgtaa acacgtggcg tttttggcat
    67381 aagacaaatt tatgagcgtt tcatcatttc gaagaaatcg tcattggtct tggtcattgc
    67441 cagtttatta atgaggaatt ccattgcatc gatttcgccc atcgggtgaa tgattttgcg
    67501 caggatccac attttctgca gttcttcctg agtcgtgagc agctcttctt tacgggtacc
    67561 agaacggttg tagtcgatag ccgggaagac gcgtttttca gcgatcttac gagagaggtg
    67621 cagttccatg ttgcctgtac ctttaaactc ttcgtagata acttcgtcca ttttagaacc
    67681 ggtatcgata agcgccgtcg cgataatggt caggctgccg ccctcttcca cgttacgcgc
    67741 cgcaccaaag aagcgtttcg gacgatgcag ggcgttggca tccacaccac cggtcaacac
    67801 tttacctgac gccggaacaa cggtgttgta agcgcgcgcc agacgagtga tggagtcgag
    67861 cagaatgata acgtctttct tgtgctcaac caggcgtttg gccttctcga tcaccatttc
    67921 cgcaacctga acgtggcgag atgcgggttc gtcaaaggta gaagcaacaa cttcaccttt
    67981 taccagacgc tgcatctcgg ttacttcttc cggacgttcg tcgatcagca gaaccatcag
    68041 cacacaatcc gggtggttgt aagcaatgct ctgagcaatg ttctgcagca gcatggtttt
    68101 accggctttc ggcggtgcca caatcagacc acgctgacca cgaccgatag gtgatgccag
    68161 atccagtacg cgagcagtta aatcttcagt agaaccgtta ccacgttcca tacgcagacg
    68221 agagtttgcg tgcagcgggg ttaagttctc aaagaggatt ttgttgcggg cgttttcagg
    68281 tttgtcgaag ttaacttcgt taactttcag cagcgcaaaa tagcgttcac cttctttcgg
    68341 cgggcgaatc ttaccagaga tggtatcacc agtgcggagg ttgaaacggc ggatttggct
    68401 aggggaaacg tagatgtcat caggaccggc gaggtaggag ctgtctgcgg aacggaggaa
    68461 accaaatcca tcctgcaata tctccagtac gccatcacca aagatatctt cgccactctt
    68521 tgcgtgctgc ttcaggatgg caaaaataat gtcctgctta cgcatacgag ccaggttttc
    68581 cagccccata ttttcgccga gagtgatcag ctcagaaacc ggcgtattct ttaattcggt
    68641 aagattcata gtggtgtgag ttcttaaact tggggtaaat ctcgaactta atgttgtgaa
    68701 tggtatggca ggatcatcca tgcctgttta cggtcatcga ctcatgtctt ttcgctgcct
    68761 ggtcacagga gagtacgcag aactgaaacg acaagacgga ttgagtgacg agccagaaat
    68821 ctgttcactt cgcatttaag ataaaacggg aagcgttgga aattacaaga ttcaaactta
    68881 ataaggtatg tttaatacga agtcaacact aagttagcat gactcacgcc gggcgtccag
    68941 tttttagcga cggggcaccc gaacatgaaa ttcccttacg ccaggttagc gtcgaggaac
    69001 tctttcaact gacctttaga cagtgcaccc actttggttg ccgccacttc accgtttttg
    69061 aacagcagca gagtcgggat accacggatg ccatatttcg gcgcagtgcc agggttttga
    69121 tcgatgttca gttttgcaac ggtcagtttg ccctgatatt cgtcagcgat ttcatccaga
    69181 atcggggcga tcattttgca cggaccgcac cactctgccc agaaatcgac gaggatcgcc
    69241 ccgtccgctt tgagtacatc cgtgtcaaaa ctgtcgtcag tcaggtgaat aattttatcg
    69301 ctcatatata actccacagg aataagcctg gcgtgttggt ttcgttgttg gtgtaacatt
    69361 aaccaactaa aggttgactt tatttcaccg gatacgcttt cgtaaagcaa tagtaagctg
    69421 atattctacc acactatgag caaaacacat ttaacagaac agaagttttc cgacttcgcc
    69481 ctgcatccga aggttgtaga agcccttgaa aaaaaagggt ttcataactg tacgcccatt
    69541 caggcactgg cccttccgct gacgctggcg ggtcgtgacg tagccgggca ggcgcaaacc
    69601 ggtaccggga aaacgatggc gtttcttacg tcaacgtttc attatcttct ctctcatcct
    69661 gcgattgccg atcgcaaggt gaatcagccg cgtgccttaa ttatggcacc gacgcgtgaa
    69721 cttgccgtgc agatccatgc cgacgcagaa ccgctggcgg aagctactgg cctgaagctg
    69781 ggtctggctt acggtggtga tggctacgac aaacagctga aagtgctgga aagcggcgtt
    69841 gacattctga ttggcaccac ggggcgttta attgactacg ccaagcagaa ccacattaac
    69901 ctcggtgcca ttcaggtggt ggtactggac gaagccgatc gcatgtacga tctgggcttt
    69961 attaaagata tccgctggct gttccgccgt atgccgcctg caaaccagcg cctcaacatg
    70021 ctgttctccg ccacgctttc gtaccgggta cgtgaactgg cgttcgagca gatgaacaat
    70081 gccgaatata ttgaagtgga accggaacag aaaacgggcc accgtattaa agaagagctt
    70141 ttctaccctt ctaacgaaga aaaaatgcgt ttgctgcaaa cgctgatcga agaagagtgg
    70201 ccagacagag cgattatttt cgccaacacc aaacaccgtt gtgaagagat ctggggccac
    70261 ctggcagcag atggtcatcg tgtcggttta ttgacaggcg atgtcgcgca gaaaaaacgt
    70321 ctgcgtattc ttgatgaatt tacccgtggc gatctggata ttctggttgc caccgacgtt
    70381 gccgcgcgtg gtttgcatat tccggcagtg acgcacgtct ttaactacga tttacccgat
    70441 gactgtgaag attacgttca ccgtattggt cgtacaggtc gcgcaggcgc aagcggtcac
    70501 tctatcagcc tggcgtgtga agagtatgca ttgaatttgc ctgctattga gacctatatt
    70561 ggtcactcaa ttccggtaag caaatacaat ccggacgcat tgatgaccga tctgccaaaa
    70621 ccgctgcgcc tcacgcgccc gcgcacaggc aatggtccgc gtcgtactgg cgctccgcgt
    70681 aatcgtcgtc gttcaggtta aataaaaaat gtcatactca aaatcattca aactgtatca
    70741 agatggcaag agaatgaatc ccgatgagct tactgtagta agtgattcag gtgaaagaat
    70801 gcagccaaca cagagacaga ttgaaggatg aagagtatgg gttccacctc gtcgctgtat
    70861 gcagccattg atctcggttc gaatagtttt catatgctgg ttgtgcgcga ggtggctgga
    70921 agcatccaga cgctgacgcg aataaaacgc aaagtgcgtc tggctgctgg cctgaatagc
    70981 gaaaatgccc tctccaatga agcaatggag cgcggttggc aatgtttgcg cctgtttgct
    71041 gaacgtctgc aagatattcc tccctcgcaa attcgcgttg tcgctacggc gacgttacgc
    71101 cttgccgtca atgcgggtga ttttattgcc aaagcgcagg aaattctcgg ttgtccggta
    71161 caggtgatca gcggtgaaga ggaagcacgt ctgatttatc agggcgttgc tcacaccact
    71221 ggtggtgccg atcagcgcct ggtggtggat ataggcggag ccagtactga actggtaacc
    71281 ggcacgggtg cacaaaccac ctcgttgttc agcctgtcga tgggctgcgt cacctggctg
    71341 gaacgctatt ttgccgatcg taatctgggg caggaaaatt ttgatgctgc agaaaaagcg
    71401 gcacgcgaag tgttacgtcc ggttgccgat gaattacggt atcacggctg gaaagtgtgc
    71461 gttggtgctt ccggcaccgt gcaggcgtta caggaaatca tgatggcaca ggggatggat
    71521 gaacgcatta ccctggaaaa gttgcagcaa ttgaaacagc gagccattca ttgcggtcgg
    71581 ctggaggaac tggagattga cgggctgacg ctggaacgtg cgttagtgtt cccgagtggt
    71641 ctggcgatcc tgatcgccat ttttaccgaa ctgaatattc agtgtatgac cctggcgggc
    71701 ggtgcgctgc gtgaaggcct ggtctacggc atgttgcatc tggccgtcga gcaggatatt
    71761 cgcagccgta cgctgcgtaa tattcaacgc cgctttatga tcgatattga tcaggcacag
    71821 cgcgtagcca aagttgcggc taacttcttc gatcaggtgg aaaacgaatg gcatcttgaa
    71881 gcaataagcc gcgatttgct catcagcgcc tgtcagcttc atgaaatcgg cctgagcgtt
    71941 gacttcaaac aagcgccgca acacgctgct tatctggtgc gtaatctgga tcttcccggt
    72001 tttacccccg cacagaaaaa attgctggcg acgctactgc tcaaccagac taatccggtc
    72061 gatctctcat cgctgcatca gcaaaatgcc gtaccgccgc gcgtcgcaga acaactctgc
    72121 cgtttactac gcctggccat catttttgcc agccgtcgcc gtgacgatct cgtgccagag
    72181 atgacattac aggctaacca tgaactgttg accttgacgc ttccgcaagg ttggctaacc
    72241 caacatccgc tgggtaaaga gattattgct caggaaagcc agtggcagag ctatgtccac
    72301 tggccgctgg aagtgcatta atgagtaagt gccggatgcg atgctgacgc atcttttccg
    72361 gccttgatta tttccctcgt tttgccgcca tcatcgcttt cagattcgcc agatggcttt
    72421 gccctttctg catccgttct tcggcgctga ccactttgcg ctcctgttcc caaatcagat
    72481 catcctgcgg cagctccagc aaaaagcggc tcggctccgg gcgcaccagt tcgccgtact
    72541 gacggcgttc tttacacagc gtaaaggtca attccttctg ggcgcgggta atgccgacat
    72601 aggccagccg ccgctcctca tcgatattat cttcatcgat gctgctctgg tgcggcaaaa
    72661 acccttcttc cataccgacc atgtagacat aaggaaactc cagccctttc gacgcgtgga
    72721 gagtcatcag ttgcacctga tccagctctt cttcactctc accacgctcc atcatgtcgc
    72781 gcaaagtaaa gcgcgtcacc acctgggtga gcgtcatcgg ctcatccagt tcactgcctt
    72841 ccagcatctc cgtcatccag ctaaacagtt ggttgacgtt cttcatgcgc atttcggcgg
    72901 ctttcgggct gggcgatgtt tcgtacagcc aggattcata atccatgcca tggatcagat
    72961 cacgcaccgc ggcaatcggc tcccgctccg ccagacgctg gatttctgcc aaccagtgag
    73021 tgaagcgggt caatgcttca taaccacgtc cgctaagcgt ctgactcagg cccatatcaa
    73081 agctggcggt aaacatgctt ttattgcgcg tcatcgccca ctcacccagc tttttcagcg
    73141 tagccgggcc aatctctcgc ttcggcgtgt taacgatacg cagaaatgcg ctgtcatcgt
    73201 ccgggttagt cagcacgcgc agataagcca gcaagtcctt gatttcagga cgagagaaaa
    73261 acgacgtacc accagatatt ttgtacggga tgcggttttg catcaggaat ttttcaaaca
    73321 cccgcgactg atggttaccg cgataaagaa tggcgtaatc tttgtactgc gttttattga
    73381 cgaagtgatg ggcgatcagc tcgccagtaa cgcgctcagc ctcatgttct tcgttattcg
    73441 cgcttaatac ttttagctcc gcgccataac ccagttcgga gaacagacgc ttttcaaaga
    73501 cgtgcgggtt attggcgatc aggatgttcg ccgctttcag aatacgcccg gaagagcgat
    73561 agttctgctc aagcttaatc accttcagcg ccggaaaatc ctgactcagc agcaccaggt
    73621 tttgcggacg tgcaccgcgc caggagtaga tcgactggtc atcgtcaccc accacggtaa
    73681 agcgcgcgcg gctgcccacc agcagtttca ccagctcata ctggctggtg ttggtgtcct
    73741 gatactcatc caccagcaga tagcgaattt tgttctgcca gcgctcgcgg acttcttcat
    73801 tgcgttgcag cagcaacgtc ggcaataaaa tcagatcatc gaagtcgaga acgttacagg
    73861 ctttcaggtg tgcatcatac agcccataac aatgggcaaa aatacggtcc cgctcgccaa
    73921 tcgcacttgc tgccgcctgg gacggtgttt tgagatcatt cttccagtta gagatggtcg
    73981 aaatcagttg ttgcaggaga actttgtcat cttcaatcag cccctcggtc aactctttaa
    74041 gcaaagcaag ctgatcggta tcgtcaaaca acgagaagtt cgctttcatc ccaagcgccg
    74101 catactcgcg tttgatgata tccagcccca acgtatggaa agtggagatc atcagcccac
    74161 gcgcctcttt gcgccccagc gtctgcccta cacgctcttt catctcgcgc gctgctttat
    74221 tagtaaaggt caccgccgca atgtgccgcg cctgataacc gcaaccgcgg atcagatggg
    74281 cgattttatt ggtgataaca cgagttttac cggaacccgc gcccgccagc accaggcagg
    74341 ggccggtaac gaattcgaca gcttgttgtt ggccggggtt tagacgcata ggtgtattgc
    74401 tcaatcttcg aacgggggga ggattgtagc agaatcgcat ttgaatgtga ccgcgtgtaa
    74461 gccgctaacc ggttggctgc ggatgtttaa atcagagaga gaagaccgaa atcggagttc
    74521 atcgtgaatc cattagactt agaaaatatc gggtcgtaac gttgtgttat tactttttca
    74581 gagtttacta aggagaggtt tactcgtggc gattaatttc agccctaagg ttggtgaaat
    74641 actggaatgc aactttggta actatcctgt tagccaaaat ggaccgttca gcacgacgta
    74701 ttacgatggc cgcattcctc ctgaaatgat aaaaaacagg ttagttgtcg tgctcaacgg
    74761 aaaaattaat ggcaacgcat gcatcgtcgt tccattatca accactcgcg accagacaag
    74821 ttaaaacgtg gaatgcatgt tgaaatagcc agtaatgtta tcaatgacct gcaattcttt
    74881 gatcagcaga ttcgttgggc caaagccgac ctggtacaac aagtcagtcg aaacagatta
    74941 aacagagcaa ggacttacag agggtatctt aatcaatgtt tgccacatga gttggttgca
    75001 gacatacaga gggcggtcat caagtcaatc aatgccatat cgctcataaa ttgacaataa
    75061 aataaccatc cccgataatg actttgtagc ccatagaggc cctaagtttt ctccccttga
    75121 gggacctgcg aagcccggat tttccgggct tttgccatat atgtaccagc cactccctga
    75181 ctgacaatta cgttagcatc tgcggatcat gctaaaatcg ccgcctgaca attattcact
    75241 caaggcacga tcatggcaaa aacagcagca gcactgcata tccttgtaaa agaagagaaa
    75301 ctggctctgg atcttctcga gcagattaag aacggggccg atttcggcaa gctggcgaag
    75361 aaacactcca tttgcccatc aggcaaacgc ggcggtgatt taggtgaatt ccgccagggt
    75421 cagatggttc cggcgttcga taaagtggtt ttctcttgtc cggtactgga gccgaccggc
    75481 ccgctgcaca cccagttcgg atatcacatc attaaggtgc tgtaccgcaa ctaatagcaa
    75541 ggccttctcc aggagaaggc cttgagtgtt ttctccctct ccctgtggga gagggtcggg
    75601 gtgagggcat cagcgcgcac ttaacccgca acagcaatac gtttcatatc tgtcatatag
    75661 ccgcgcagtt tcttacctac ctgctcaatc gcatggctgc gaatcgcttc gttcacatca
    75721 cgcagttgcc cgttatctac cgcgccttcc ggaatagctt tacccaggtc gcccggttgc
    75781 agctctgcca taaacggttt cagcaacggc acacaagcgt aagagaacag atagttaccg
    75841 tactcagcgg tatcagagat aaccacgttc atttcgtaca gacgcttacg ggcgatggtg
    75901 ttggcaatca gcggcagctc gtgcagtgat tcataatatg cagactcttc aatgatgccg
    75961 gaatcgacca tggtttcgaa cgccagttca acgcccgctt tcaccatcgc aatcatcagt
    76021 acgcctttat cgaagtactc ctgctcgccg attttgcctt catactgcgg cgcggtttca
    76081 aacgcggttt tgccggtctc ttcacgccag gtcagcagtt tcttatcatc gttggcccag
    76141 tccgccatca taccggaaga gaattcgccg gagatgatgt cgtccatatg tttctggaac
    76201 aggggtgcca tgatctcttt cagctgttca gaaagcgcat aagcacgcag tttcgccggg
    76261 ttagagagac ggtccatcat cagggtgatg ccgccctgtt tcagtgcttc ggtgatggtt
    76321 tcccaaccga actgaatcag tttttctgcg tatgctggat cggtaccttc ttccaccagc
    76381 ttgtcgaagc acagcagaga gccagcctgc aacataccgc acaggatggt ttgctcgccc
    76441 atcaggtcag atttcacttc cgcaacgaag gacgattcca gcacacccgc acggtgacca
    76501 ccggttgcag ccgcccaggc tttggcaatc gccatgcctt cgcctttcgg atcgttttcc
    76561 gggtgaacgg caatcagcgt cggtacgccg aacccacgtt tgtactcttc acgcacttcg
    76621 gtgcctgggc atttcggcgc aaccatcact acggtgatat ctttacggat ctgctcgccc
    76681 acttcgacga tgttgaaacc gtgcgagtag cccagcgccg cgccgtcttt catcagtggc
    76741 tgtacggtgc gcactacatc agagtgctgc ttgtccggcg tcaggttaat caccagatcc
    76801 gcctgtggga tcagttcttc gtaagtaccc actttaaaac cattttcggt cgctttacgc
    76861 caggacgcgc gcttctcggc aatcgcttct ttacgcagag cgtaggagat atcgagacca
    76921 gaatcacgca tgttcaggcc ctggttcaga ccctgtgcgc cacagccgac gatgactact
    76981 tttttaccct gaaggtagct cgcgccatcg gcgaattcat cgcggcccat aaagcgacat
    77041 ttgcccagct gtgccagctg ctggcgcaga ttcagtgtat tgaagtagtt agccatggtg
    77101 attcctcgtg atgttgtgct tcttattgtt cggttcgcgt ttgcgagatt gaattcacta
    77161 tatgacagga aatttattgc ggaaattgat atattcacaa cgtcacattg caatttttgc
    77221 aacgtcaaca tcgagggctg tccctgtgga tttacgcgat ctgaaaacct tcctgcatct
    77281 ggcggaaagc cgccattttg gccgcagcgc gcgggcgatg cacgttagcc catccacgct
    77341 ctcacggcag attcagcgcc tggaagaaga tctcggtcag ccgctgtttg tgcgcgataa
    77401 ccgcacggtg acgctgactg aagcgggcga agagctgcgc gttttcgccc agcaaacgct
    77461 gttgcagtat cagcagttgc gccacaccat cgatcagcaa gggccgtcgc tctctggcga
    77521 attacatatc ttctgctcgg tgaccgctgc ctacagccat ctgccgccga ttctggatcg
    77581 cttccgcgcg gaacacccgt cggtggagat taaacttact actggtgatg cggcagatgc
    77641 gatggaaaag gtggtcactg gtgaagcgga tctggcgatt gcgggtaaac cggaaacctt
    77701 gcccggcgca gtggcgtttt cgatgctgga gaatctggca gtagtgctga ttgcccccgc
    77761 gctgccctgc ccggtgcgta atcaggtgtc ggtagagaag ccggactggt caacggtgcc
    77821 gtttattatg gccgatcagg ggccggtacg ccgccgcatt gaactgtggt ttcgacgcaa
    77881 taaaatcagt aacccgatga tttacgccac ggttggcggg catgaagcga tggtatcgat
    77941 ggtggcactc ggctgtggcg tggcattgtt gccggaagtg gtgctggaaa acagccccga
    78001 accggtgcgt aaccgcgtga tgattttaga gcgcagcgat gagaaaacgc cgtttgagct
    78061 gggcgtgtgt gcgcagaaaa agcggctaca tgagccgcta attgaggcat tctggaagat
    78121 tttgccgaac cacaaatgac gttgtcgcgc gggtaggcct gataagcgaa gcgctatcag
    78181 gcatttttcc ctaacccgcc aaaaagaacc tgaacgccgg gttattggtt tcgtcgtggc
    78241 aatcgtagcc cagctcattc agccgggttt cgaaatccgg ttcatggtcg ccaagttcga
    78301 acgccgccag tacgcgcccg tagtcggtgc catggctgcg atagtggaac aaagaaatgt
    78361 tccagtacgt acccagcgtg ttgaggaagc gcagcagcgc gcccggtgat tccgggaatt
    78421 cgaagctgta gaggcgttcc tgcaacggat gcgatggacg tccgccgacc atatagcgca
    78481 cgtgtagctt cgccatttcg tcgtcggaga gatcaaccac gctgtagccg ccgtcgttga
    78541 gcatctgcaa aatttctttg cgctcttcga ggccgcggct caggcgcaca ccgacaaaga
    78601 tgcaggcgtt tttggcatcg gcaaaacggt agttgaactc ggtgaccgaa cgcccgccaa
    78661 gcagttggca gaatttgagg aagctgcctt tttcttccgg aatggtcacc gccaacaacg
    78721 cttcacgctg ttcgcccagt tcgcagcgtt ctgagacgta gcgcaggccg tggaagttca
    78781 cgttggcacc ggaaagaata tgcgccagcc gttcgccgcg aatgttgtgc agggcgatat
    78841 attttttcat tcccgccagc gccagcgcgc cagagggttc cgccaccgcg cgcacatctt
    78901 cgaataaatc cttcatcgcc gcacagatcg catcgctatc gacggtgatg atgtcgtcga
    78961 gatactcctg gcataaacgg aaggtttcgt caccgatgcg ttttaccgct acgccttcag
    79021 caaatagccc tacgcgcggc agatcaaccg gatgacccgc atccagcgct gctttcaggc
    79081 aggcggagtc ttccgcttct acggcgatca ctttgatttg cggcatcagt tgtttgatca
    79141 gcaccgccac gccagcagcc agaccgccgc cgccgactgg cacaaatacg cggtcgagat
    79201 gggcgtcctg ctggagcagt tccagcgcca gcgtgccttg cccggcaatc accatcggat
    79261 ggtcgaacgg cggcacccag gtgaacccct gctgctgtga cagttcgatc gctttggctt
    79321 tcgcttcatc aaagttcgcg ccgtggagca gcacttcgcc gccgaagccg cgcaccgcgt
    79381 cgactttgat gtcggcggtg gcggttggca taacgatcag ggccttcacg cctaaccgcg
    79441 cagaagaaaa cgcgacgccc tgcgcgtggt tacccgcaga agcagtgatc acgccgtgcg
    79501 ctttctgttc ttccgtcagg cccgccatca tggcgtatgc gccgcgcagc ttaaagctgt
    79561 gcactggctg gcgatcttcg cgcttcacca gaatgacgtt atcaagacgc gacgacagtt
    79621 tttccatttt ttgtagcggc gtaacctgcg ccgcctcgta aaccggcgcg cgcagcactg
    79681 ctcttaaata ttcggcacct tccggagcac cggacagggg ttgcgagtca gccattatta
    79741 accccccagt ttcgatttat cgcgcaccgc gcctttgtcg gcgctggttg ccaggctggc
    79801 ataagcacgc agggcaaagg agacctgacg ttcacgattt ttcggcgtcc aggctttgtc
    79861 acctcgagcg tcctgcgctt cacgacgcgc cgccagttcg gcatcgctta cctgtaactg
    79921 aatgccacgg ttcgggatgt cgatagcgat caggtcacca tcttcaatca ggccaatgct
    79981 gccgccgctt gccgcttccg gtgagacgtg gccgatggaa agaccagagg tgccaccaga
    80041 gaaacgaccg tcggtgatca gcgcacaggc tttgccgaga cccattgatt tcaggaagct
    80101 ggttgggtag agcatttcct gcatccccgg accgcctttc gggccttcat agcgaattac
    80161 taccacatct ccggcgacaa ctttaccgcc gagaatcgct tctaccgcat cgtcctggct
    80221 ttcgtacact ttcgccgggc cggtgaattt gaggatgctg tcatcgacgc ctgccgtttt
    80281 cacgatgcag ccgttttccg caaagttacc gtagagcacc gccaggccgc cgtctttgct
    80341 gtaggcgtgt tccagcgagc ggatacagcc attggcgcga tcgtcgtcca gcgtatccca
    80401 acggcaatct tgcgagaatg cctgtgtggt acgaatgcct gcaggacctg cgcggaacat
    80461 attttttacc gcgtcatcct gggtcagcat aacgtcgtat tgttccagcg tttgcggcaa
    80521 cgtcaggcca agtacgtttt tcacatcacg gttcagtaac cccgcgcgat ccagttcgcc
    80581 gagaataccg ataacaccac cagcacggtg aacatcttcc atatggtatt tctgggtgct
    80641 cggcgcaact ttacacagct gtggaacctt gcgggaaagc ttatcgatat cactcatggt
    80701 gaagtcgatt tccgcttcct gcgccgccgc cagcaggtga agtacggtgt tagtcgatcc
    80761 acccatcgcg atatccagcg tcatggcgtt ttcaaacgcc gccttactgg cgatattacg
    80821 cggcagtgca ctttcgtcgt tttgctcgta ataacgtttg gtcaattcaa caatgcgttt
    80881 accagcatta aggaacagct gcttacggtc ggcgtgggtt gccagcagcg agccgttgcc
    80941 cggctgcgac aggcccagcg cttcggtcag gcagttcatt gagttagcgg taaacatccc
    81001 ggagcaggaa ccgcaggtcg gacacgcgga acgttcaacc tgatcgctct gggagtcaga
    81061 tactttcggg tctgcgccct ggatcatcgc atcaaccaga tcgagcttga tgatctgatc
    81121 ggaaagtttg gttttcccgg cctccatcgg gccgccggaa acaaagatca ccggaatatt
    81181 caggcgcagg gaagccatca gcatccccgg ggtgattttg tcgcagttag agatgcagac
    81241 catggcgtcg gcgcagtggg cgttgaccat atactcaacg gaatcagcga tcagttcgcg
    81301 agatggcagt gaataaagca tccccccgtg gcccatggca atcccatcat ccaccgcaat
    81361 ggtgttgaac tctttggcaa cgccgccagc cgcttcaatt tgttcggcga ccagtttacc
    81421 gagatcgcgc agatggacgt gacccggtac aaattgggtg aacgagttca caaccgcgat
    81481 aatcggctta ccgaaatcgg cgtcggtcat tccggtggcg cgccacagcg cacgagcacc
    81541 cgccatatta cgaccatgag tggtggtggc ggaacggtac ttaggcatac tttatttact
    81601 cccagtgtct gtctcgtaaa tgggacggtg cgtgccgtcc cattttttgt atttattgat
    81661 taacttgatc taaccagccc catttatctt cggtttcgcc agtgaagagg ccgaagaagg
    81721 cttgctgaat gcgtttggta accgggccac aacggccttc gccaacctga ataccgtcta
    81781 cgctgcgcac tggcgtgatt tctgccgccg taccggacat aaacacttca tccgccaggt
    81841 acagggattc gcgcgacagc acctgctcac gtacttcaat tcccagctct ttcgccagtt
    81901 tgatgatggc atcacgggta atacccggca gcgcggagga ggtgaacggt ggggtgaaca
    81961 gcacaccatc tttcacttca aacaggtttt cgcctgcgcc ttcagagata taaccgttca
    82021 catccagcgc gataccttcc tgataaccgt ggcggcgcgc ttcgctaccc accagcaggg
    82081 aagagaggta gttaccaccg gcttttgccg ccgtcgggat ggtgtttggt gctgcgcggt
    82141 tccaggagga aaccatcgca tcgatcccct gctccagcgc ttctgcgccc agatacgctc
    82201 cccacgggaa agcagcgata atcacgtcgg ttgagtatcc cgctggcggg tttactccca
    82261 tgccaacatc accgacgaag atcagcggac ggatataggc gctggtgaga ttgtttttgc
    82321 ggatcacgtc acgacaagct tccatcagct catcaatgct ctgcgaaacc gggaagcgat
    82381 agattttggc ggagtcatgc agacgctgca tatgctcacg atggcggaat acaaccggtc
    82441 ctttgtgcga gtcgtagcaa cggatgcctt caaaaaccga agtgccatag tgcagcgcgt
    82501 gcgacatcac atgcaccttc gcgtcttccc agcgaaccat ctccccattg aaccaaatgt
    82561 aatcagcttt cttcgtggtc atttttatat tccttttgcg ctcaggcgcg gatttgttgt
    82621 gatgtggttg tgctctggca gatggcaacg tgtgcgacgt ccaccagttt atttaactga
    82681 ctaaacagta agtcgaccga ccgtgggctg gcaacggtca attcgatatt tatattttgt
    82741 gcatcgctgg cggcggccat attcattgag cagacgtgga aaccacgatg acgcaccacg
    82801 cgtaaaacac gttctaaggt ttctggattg aagcgagccg atacattgac ctgatgttgc
    82861 atcatgataa tttctccaac atttctgaat tactggcgcc aggcggcacc agcggccaga
    82921 cgttctcaag ttcgtcgatt gagacatgaa gcaggtatgg cccatcactg ttcagcatgg
    82981 tgtcgagtgc cgcttcaacc tggtctttcc gggtgatgtg ttggccatgg atgccgaagg
    83041 cgctggctaa catgaggaaa tcggggttat cagtaagggt ggtttcgctg tatcgttcct
    83101 gaaaaaacag ttgctgccat tgtcgaacca tccctaaccg ttggttatcg agtaagacga
    83161 ttttcaacgg taactgcttg cgttttacgg tgcccagctc ttgcacattc atcatgaaag
    83221 agccgtcacc ggagatacag acaacggtat cgttcggtcg cgcgacttgt gcgccaaccg
    83281 ccgccggtaa accaaaaccc atggtaccta aaccgctgga ggtgatgaaa ttttccgggc
    83341 gagtgtgggc gatgtgctgc gcagcccaca tctggtgctg ccccacatct gtggtcacga
    83401 cgcaatccgc aggtttacga tccgacagtt gttttaacaa caacggcgcg tagatagcgt
    83461 caccgggatg gtcgtaacgc caggaatgtt catcacgcag ctgcgcgcag tgttgctgcc
    83521 agtcattgat atttaacggc tgctgtaatg ctggtaacag agcatttaaa tcaccttgta
    83581 atgccacatg tgcctgacgc agcttgttca tttctgccgg gtcgatatcc atatggataa
    83641 cactggcgtg tggcgcgaag gtgttcagtt tgccggtcac ccggtcatca aaacgtgcgc
    83701 ccacggcgat cagcaggtca cactcctgca ccgcgaagtt tgccgctttg gtgccgtgca
    83761 tccccagcat gcccagatag tacggataat ctgcttctac tgcgcccagc cctttcagcg
    83821 tacaggtggc aggcattttt gtggcagcga gaaattcacg caaagccgga actgcctgcg
    83881 ccatacccac gccaccgcca acgtacagca tcggtttttg cgcttttgcc agcatctggc
    83941 gcgcttgctc aacttcggca tgtgggaaag tcacttcgtt ttcaacggtg gtgaaccacg
    84001 gttccaggtc accgctggct aactggatat cttttgggat atcgaccaga accggaccag
    84061 gacgacctga gcaggcaacg tcgaatgctt cagccatgat gcgcggcaac tcttccagcg
    84121 actgcaccag aaagctgtgc ttggtacagg ctaacgacaa tcccaggaca tccacttcct
    84181 gaaatgcgtc agtgccgata aacggtgcgg acacttgacc ggtgatggca acaacaggga
    84241 tggaatctaa cagtgcgtcc gcaagcccgg ttatcaggtt ggttgcgccc ggaccagacg
    84301 tggcgataca tacgccagtt ttgccggtag cacgagcata accgatagcc gccattgccg
    84361 caccctgctc atgtcggcat agcaagtgct ccacgccgcc gtcatacaat gcatcgtaaa
    84421 ccggcataat tgcgccaccc ggataaccga aaacggtgtt cacaccctgt gcccgcaacg
    84481 catgtaccac ccactgtgcg ccattcatag ttagttcccc gtcctgaatc ttgagaaaca
    84541 gaattttgtg ctgttattca ttgtctgctc ctcggttatg tttttaaggt caaaaaaaac
    84601 ccccggacct ttcggtgcgg gggtcttagt tcgttaaggc ttgatctcta agcctttcct
    84661 cgtccaagtg cagccccgca cggtgggata ataatcacca ccacgctaat cacgaccagg
    84721 ctaatcactc gtagaagggc tgtcattttg tcttttcttg catcttgttc gaaggaatgt
    84781 ctaaagagtt accataggtt ttgtaaatag tacaagatat tttttggccg atttttatga
    84841 tgcgtttaat aatttcaata taaattgttg ttttttaaaa ataaaatagt gagtgaaaaa
    84901 aattcaattt cagtatgaat gttgttccct tcctcgtagt tcatcctttg tccgctgcat
    84961 ttttgcgagc atcattccac cgccagaaca actcaacttc acttgcacaa ataaacagga
    85021 atcagccact aaaattcacg aattagcggg ctacagcagc gatatcttat gcacataatg
    85081 gtgactcaag gagggcttat gtcactgtca attgttcata cccgcgcagc cctgggagta
    85141 aatgcgcccc cgatcactgt tgaggtacat atcagtaaag gtctacccgg cttaacgatg
    85201 gtgggcttac cagaaacaac ggtaaaagaa gctcgcgatc gcgtgcgcag cgccattatc
    85261 aatagcggat atgaatatcc ggcgaaaaaa atcaccatca acctggctcc agctgatctg
    85321 ccaaaagaag ggggacgata tgatttacct atcgccattg cgttgctggc ggcctcagaa
    85381 cagcttacag ccaataagtt agatgaatat gaattagtcg gagaactggc gcttacaggc
    85441 gctctgcgtg gcgttcccgg cgcaatctcc agtgcaactg aagctattaa gtcgggcaga
    85501 aaaattatcg tcgcgaaaga taacgaagat gaagtggggc taattaacgg tgaaggatgc
    85561 ctgatagccg atcatctgca agctgtctgt gcgtttctgg aaggtaagca cgctctcgaa
    85621 cgcccgaaac caactgatgc agtatcccgg gcgctacaac atgatctcag tgatgttatc
    85681 ggtcaggaac aaggaaagcg aggactggaa attaccgctg ctggcgggca caacatttta
    85741 ctgattgggc cgccgggaac aggtaaaaca atgctcgcca gccgtattaa tggcctgttg
    85801 ccagatttaa gcaatgaaga ggcactggag agtgctgcga tattaagtct ggtaaatgct
    85861 gaatcagtac aaaaacaatg gcggcagcgc ccgttccgct cacctcatca cagtgcatcg
    85921 ttaactgcga tggtaggcgg tggcgcaatt ccagggcccg gtgaaatttc gctggcgcat
    85981 aacggcgtgc tttttcttga tgagctacct gaatttgaac ggcgtacact ggatgccttg
    86041 cgagagccga ttgaatccgg gcagatccat ctttcacgca cacgagcaaa aataacctat
    86101 ccagcccgtt tccagcttgt tgcggcgatg aatcccagcc ctaccggaca ttatcaggga
    86161 aaccataacc gctgcacgcc agaacagaca ttacgttatc tcaaccggct ctcggggccc
    86221 tttctcgacc gcttcgatct ctcactggag atcccattac caccccccgg cattttgagt
    86281 aaaacggtag tgccgggaga aagcagcgcc accgttaaac aacgcgtaat ggccgccaga
    86341 gagcgccaat ttaagcggca gaataaactg aatgcctggc tggatagtcc ggaaatacgc
    86401 caattctgca aacttgagag cgaagatgcg atgtggttgg aaggaacact gatccatctg
    86461 gggttatcga ttcgtgcctg gcagcggtta ttgaaagttg cacgaaccat tgctgatatt
    86521 gatcagtctg acattatcac acgtcagcat ttgcaggagg cagttagcta tcgagcgatt
    86581 gaccgtttgc tcatccatct gcagaaacta ctgacataaa aaaagggcat ttcgcccttt
    86641 ttattaatcg tcagaatcgg tgtagtcttc agcaccttca acctgcggtt taccgccgga
    86701 aagggtgtga aaacgttttg gacgcttaat acgcgtcata tacttggacc acacgcgttc
    86761 tgcttctgtc actggctcac gttcgccacg gcatactgct acgaagagtt tctcttcctc
    86821 ggtaaccggc tcgcgtttgc caagatccaa ctcattgaag gcataaccat gacgctcaag
    86881 cagttgtgcc tctttgatgg tgaaatcacc atgacgagag aatccacgtg gataatgttt
    86941 attgtcgaaa tatcgattag tcgtcgtaaa gctttccgcc atcctgcacg ctcctaattc
    87001 tttgaccgag ctagttatgg cgcggagtat tagttacgct tgacagagtg taaaacaaaa
    87061 catttaaatc ataacgacaa ataattttgc ggagagcact gtggatacgg aattgttaaa
    87121 aactttcctg gaagttagcc gaacgcgtca ctttggtcga gcggctgaat cgctctatct
    87181 gacccagtca gcagtgagct ttcgaatcag acaactggaa aatcaactgg gtgtgaacct
    87241 tttcacccgc cacagaaaca atatccgttt aaccgctgcc ggtgaaaaac tactgcctta
    87301 tgcagaaacg ctcatgagca cctggcaggc cgcccgtaag gaggtggcgc atacctcacg
    87361 acataacgag ttttctatcg gtgccagcgc ctcgttgtgg gaatgtatgc ttaatcagtg
    87421 gctgggacgc ttgtatcaaa atcaggatgc ccatacaggc ttacagttcg aagcgcgaat
    87481 tgcccaacgg cagtctctgg taaaacagct gcatgaacgc cagcttgatc ttcttattac
    87541 cactgaagcg cccaaaatgg acgaatttag tagtcagttg ctgggatatt tcactttagc
    87601 gctttatacc agtgcccctt caaaactaaa gggagatctt aattatctgc gacttgagtg
    87661 ggggccagat tttcaacagc atgaggcagg tttgatcggt gctgacgaag tgcccattct
    87721 gacaaccagt tctgctgaac tggcacagca acagattgcg atgcttaatg gttgcacctg
    87781 gctacccgtc agctgggcgc gtaaaaaagg cggcctgcat accgttgtcg atagcacaac
    87841 actttcacgg ccgctttatg ccatatggct gcaaaatagc gataaaaatg cgttgattcg
    87901 cgatcttttg aaaattaacg tgctggatga agtgtattaa tatgaatggc tggcaaggat
    87961 gccggtagaa ggatttactt cggagagggt tatttcagat aaaaaaaatc cttagctttc
    88021 gctaaggatg atttctggca ggggcggaga gactcgaact cccaacaccc ggttttggag
    88081 accggtgctc taccaattga actacgcccc taattagg
//
LOCUS       DACAOP010000006        86679 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.006, whole genome shotgun sequence.
ACCESSION   DACAOP010000006 DACAOP010000000
VERSION     DACAOP010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 86679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86679
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.006"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..84
                     /locus_tag="IT892_000445"
     ncRNA           <1..84
                     /ncRNA_class="other"
                     /locus_tag="IT892_000445"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            361..1404
                     /gene="nadA"
                     /locus_tag="IT892_000446"
     CDS             361..1404
                     /gene="nadA"
                     /locus_tag="IT892_000446"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HAP3133689.1"
                     /translation="MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVM
                     VAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEK
                     TILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
                     ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEY
                     PDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPD
                     KELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEGSNHEVHVDERLRERALVP
                     LNRMLDFAATLRG"
     gene            1442..2161
                     /locus_tag="IT892_000447"
     CDS             1442..2161
                     /locus_tag="IT892_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HAP3133690.1"
                     /translation="MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEK
                     ISNYFFGLINVTLFGIIFFQIQLYASLLLQVFFFAANIYGWYAWSRQTSQNEAELKIR
                     WLPLPKALSWLAVCVVSIGLMTVFINPVFAFLTRVAVMIMQALGLQVVMPELQPDAFP
                     FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYIILTFIA
                     LNGSRMWINSARERGSRALSH"
     gene            complement(2158..3099)
                     /gene="zitB"
                     /locus_tag="IT892_000448"
     CDS             complement(2158..3099)
                     /gene="zitB"
                     /locus_tag="IT892_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc transporter ZitB"
                     /protein_id="HAP3133691.1"
                     /translation="MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGS
                     LALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVIT
                     ILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
                     LGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPV
                     SLDIAELKRRMCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYL
                     MDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH"
     gene            complement(3213..3593)
                     /locus_tag="IT892_000449"
     CDS             complement(3213..3593)
                     /locus_tag="IT892_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133692.1"
                     /translation="MKMTKLATLFLTATLSLASGAALAADSGAQTNNGQANAAADAGQ
                     VAPDARENVAPNNVDNNGVNTGSGGTMLHSDGSSMNNDGMTKDEEHKNTMCKDGRCPD
                     INKKVQTGDGINNDVDTKTDGTTQ"
     gene            3909..4961
                     /gene="aroG"
                     /locus_tag="IT892_000450"
     CDS             3909..4961
                     /gene="aroG"
                     /locus_tag="IT892_000450"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HAP3133693.1"
                     /translation="MNYQNDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIH
                     KILKGNDDRLLVVIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTV
                     GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
                     AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHS
                     AIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKAGLPAQVMIDFSHANSSKQFK
                     KQMDVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGEPLAYGKSITDACIGWEDT
                     DALLRQLANAVKARRG"
     gene            complement(5119..5871)
                     /gene="gpmA"
                     /locus_tag="IT892_000451"
     CDS             complement(5119..5871)
                     /gene="gpmA"
                     /locus_tag="IT892_000451"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP3133694.1"
                     /translation="MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKL
                     LKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAE
                     TAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDR
                     VIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEF
                     DENFKPLKRYYLGNADEIAAKAAAVANQGKAK"
     gene            complement(6073..7113)
                     /gene="galM"
                     /locus_tag="IT892_000452"
     CDS             complement(6073..7113)
                     /gene="galM"
                     /locus_tag="IT892_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-epimerase"
                     /protein_id="HAP3133695.1"
                     /translation="MLNETPALAPDGQPYRLLTLRNNAGMVVTLMDWGATLLSARIPL
                     SDGSVREALLGCASPECYQDQAAFLGASIGRYANRIANSRYTFDGETVTLSPSQGVNQ
                     LHGGPEGFDKRRWQIVNQNDRQVLFALSSDDGDQGFPGNLGATVQYRLTDDNRISITY
                     RATVDKPCPVNMTNHVYFNLDGEQSDVRNHKLQILADEYLPVDEGGIPHDGLKSVAGT
                     SFDFRSAKIIASEFLADDDQRKVKGYDHAFLLQAKGDGKKVAAHVWSADEKLQLKVYT
                     TAPALQFYSGNFLGGTPSRGTEPYADWQGLALESEFLPDSPNHPEWPQPDCFLRPGEE
                     YSSLTEYQFIAE"
     gene            complement(7107..8255)
                     /gene="galK"
                     /locus_tag="IT892_000453"
     CDS             complement(7107..8255)
                     /gene="galK"
                     /locus_tag="IT892_000453"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001713229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAP3133696.1"
                     /translation="MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVL
                     PCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKH
                     LQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE
                     AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTL
                     VGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTV
                     EAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGG
                     GFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC"
     gene            complement(8259..9305)
                     /gene="galT"
                     /locus_tag="IT892_000454"
     CDS             complement(8259..9305)
                     /gene="galT"
                     /locus_tag="IT892_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HAP3133697.1"
                     /translation="MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQV
                     LPAHDPDCFLCAGNVRVTGDKNPDYTGTYVFTNDFAALMSDTPDAPESHDPLMRCQSA
                     RGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGC
                     SNPHPHGQIWANSFLPNEAEREDRLQKEYFAEQKSPMLVDYVQRELADGSRTVVETEH
                     WLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPY
                     SMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAER
                     LRAVSDIHFRESGV"
     gene            complement(9315..10331)
                     /gene="galE"
                     /locus_tag="IT892_000455"
     CDS             complement(9315..10331)
                     /gene="galE"
                     /locus_tag="IT892_000455"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415280.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAP3133698.1"
                     /translation="MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVI
                     ERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVN
                     GTLRLISAMRAANVKNFIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
                     TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIF
                     GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVNAF
                     SKACGKPVNYHFAPRREGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQ
                     GYPD"
     gene            complement(10592..12064)
                     /gene="modF"
                     /locus_tag="IT892_000456"
     CDS             complement(10592..12064)
                     /gene="modF"
                     /locus_tag="IT892_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter ATP-binding protein
                     ModF"
                     /protein_id="HAP3133699.1"
                     /translation="MSSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSA
                     LARALAGELPLLKGERQSQFSHITRLSFEQLQKLVSDEWQRNNTDMLGPGEDDTGRTT
                     AEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
                     EPFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGA
                     KEELLQQALVAQLAHSEQLEGVQLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPIL
                     NNLSWQVNPGEHWQIVGPNGAGKSTLLSLVTGDHPQGYSNDLTLFGRRRGSGETIWDI
                     KKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDK
                     RTADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISE
                     GETQLLFVSHHAEDAPACITHRLEFVPDGGLYRYVLTKIY"
     gene            complement(12132..12920)
                     /gene="modE"
                     /locus_tag="IT892_000457"
     CDS             complement(12132..12920)
                     /gene="modE"
                     /locus_tag="IT892_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum-dependent transcriptional regulator"
                     /protein_id="HAP3133700.1"
                     /translation="MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGIS
                     YKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTRYGQRLIQLYDLLAQIQQKAFDV
                     LSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKV
                     AITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCE
                     VLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSVIIATLC"
     gene            13049..13198
                     /locus_tag="IT892_000458"
     CDS             13049..13198
                     /locus_tag="IT892_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump-associated protein, AcrZ
                     family"
                     /protein_id="HAP3133701.1"
                     /translation="MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQ
                     PGQNH"
     gene            13365..14138
                     /gene="modA"
                     /locus_tag="IT892_000459"
     CDS             13365..14138
                     /gene="modA"
                     /locus_tag="IT892_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3133702.1"
                     /translation="MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDI
                     ATQFKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQ
                     TLLGNSLVVVAPKASVQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKL
                     GAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGIKVVATFPEDSHKKV
                     EYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTIK"
     gene            14138..14827
                     /gene="modB"
                     /locus_tag="IT892_000460"
     CDS             14138..14827
                     /gene="modB"
                     /locus_tag="IT892_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HAP3133703.1"
                     /translation="MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGK
                     ALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVM
                     SFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
                     LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEW
                     LARISRERAGR"
     gene            14830..15888
                     /gene="modC"
                     /locus_tag="IT892_000461"
     CDS             14830..15888
                     /gene="modC"
                     /locus_tag="IT892_000461"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein
                     ModC"
                     /protein_id="HAP3133704.1"
                     /translation="MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAI
                     SGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMS
                     KSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
                     IPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWG
                     SSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQ
                     ASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELA
                     IKPGLWLYAQIKSVSITA"
     gene            complement(15889..16707)
                     /locus_tag="IT892_000462"
     CDS             complement(15889..16707)
                     /locus_tag="IT892_000462"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphatase"
                     /protein_id="HAP3133705.1"
                     /translation="MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTG
                     RHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHI
                     HGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
                     THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENV
                     VAFGDSFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI"
     gene            16862..17857
                     /gene="pgl"
                     /locus_tag="IT892_000463"
     CDS             16862..17857
                     /gene="pgl"
                     /locus_tag="IT892_000463"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HAP3133706.1"
                     /translation="MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVS
                     PDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYN
                     AGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG
                     HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTL
                     DMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQ
                     PRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH"
     gene            complement(17898..18851)
                     /locus_tag="IT892_000464"
     CDS             complement(17898..18851)
                     /locus_tag="IT892_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308823.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3133707.1"
                     /translation="MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEED
                     LHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPT
                     AVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFT
                     PLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLD
                     WFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKD
                     AVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG"
     gene            19035..20087
                     /locus_tag="IT892_000465"
     CDS             19035..20087
                     /locus_tag="IT892_000465"
                     /EC_number="5.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalomesaconate tautomerase"
                     /protein_id="HAP3133708.1"
                     /translation="MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGND
                     LEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGA
                     FAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVA
                     LTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELD
                     ADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRA
                     LAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRAS
                     VIRTTRKIFSGEVYLP"
     gene            20163..21596
                     /locus_tag="IT892_000466"
     CDS             20163..21596
                     /locus_tag="IT892_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HAP3133709.1"
                     /translation="MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIV
                     GLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAA
                     FVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSV
                     AVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISW
                     GGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLG
                     VFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGII
                     GLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAML
                     PVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGA
                     VLTILTFLVHITLGVWWWNMLIGWNML"
     gene            21779..24040
                     /locus_tag="IT892_000467"
     CDS             21779..24040
                     /locus_tag="IT892_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydratase"
                     /protein_id="HAP3133710.1"
                     /translation="MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSS
                     HNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGT
                     INGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTM
                     AVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVK
                     NKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQL
                     NPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAH
                     GKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
                     SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREG
                     SKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQG
                     FVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRS
                     NPIGLAEFTLSRRDPGYVSRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPL
                     QTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQM
                     AEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIK
                     AGSLINFNKNRQM"
     gene            complement(24274..25557)
                     /locus_tag="IT892_000468"
     CDS             complement(24274..25557)
                     /locus_tag="IT892_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioester hydrolase"
                     /protein_id="HAP3133711.1"
                     /translation="MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPI
                     LSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVD
                     AAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPA
                     DWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENT
                     LGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVT
                     NSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFN
                     AFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVD
                     DNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK"
     gene            complement(25709..26185)
                     /locus_tag="IT892_000469"
     CDS             complement(25709..26185)
                     /locus_tag="IT892_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase inhibitor"
                     /protein_id="HAP3133712.1"
                     /translation="MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTK
                     SFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTG
                     YDGAAPPKGETHRYIFTVHALDIERIDVDEGASGAMVGFNVHFHSLASASITAMFS"
     gene            complement(26244..27533)
                     /gene="bioA"
                     /locus_tag="IT892_000470"
     CDS             complement(26244..27533)
                     /gene="bioA"
                     /locus_tag="IT892_000470"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HAP3133713.1"
                     /translation="MTTDDLAFDQRHIWHPYTSMTSPLPVYPVVSAEGCELILSDGRR
                     LVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQP
                     LECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNS
                     MHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAG
                     GMRMYHPEWLKRIRKICDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKAL
                     TGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQQ
                     QVADIEVQLREQLAPARDAEMVADVRVLGAIGVVETTHPVNMAALQKFFVEQGVWIRP
                     FGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ"
     gene            27620..28660
                     /gene="bioB"
                     /locus_tag="IT892_000471"
     CDS             27620..28660
                     /gene="bioB"
                     /locus_tag="IT892_000471"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HAP3133714.1"
                     /translation="MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVST
                     LLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAW
                     KNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEF
                     YGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPES
                     VPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMC
                     FMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMT
                     PDTDEYYNAAAL"
     gene            28657..29811
                     /gene="bioF"
                     /locus_tag="IT892_000472"
     CDS             28657..29811
                     /gene="bioF"
                     /locus_tag="IT892_000472"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HAP3133715.1"
                     /translation="MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNF
                     SSNDYLGLSHHPQIIRAWQQGAEQFGIGSGGSGHVSGYSVVHQALEEELAEWLGYSRA
                     LLFISGFAANQAVIAAMMAKEDRIAADRLSHASLLEAASLSPSQLRRFAHNDVTHLAR
                     LLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRG
                     SCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQAL
                     RASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQL
                     AEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG"
     gene            29798..30553
                     /gene="bioC"
                     /locus_tag="IT892_000473"
     CDS             29798..30553
                     /gene="bioC"
                     /locus_tag="IT892_000473"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HAP3133716.1"
                     /translation="MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYT
                     HVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATA
                     TFDLAWSNLAVQWCGNLSTALRELYRVVRPKGVVAFTTLVQGSLPELHQAWQAVDERP
                     HANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRIL
                     TRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE"
     gene            30546..31223
                     /gene="bioD"
                     /locus_tag="IT892_000474"
     CDS             30546..31223
                     /gene="bioD"
                     /locus_tag="IT892_000474"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HAP3133717.1"
                     /translation="MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGS
                     EKTPEGLHNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAG
                     LRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTA
                     QVIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGK
                     YINLALL"
     gene            31802..33823
                     /gene="uvrB"
                     /locus_tag="IT892_000475"
     CDS             31802..33823
                     /gene="uvrB"
                     /locus_tag="IT892_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HAP3133718.1"
                     /translation="MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSG
                     KTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYV
                     PSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
                     LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFD
                     EEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLE
                     NNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGL
                     LVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYV
                     SATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVL
                     VTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLRE
                     GLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIG
                     ETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVP
                     MDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS"
     gene            complement(34015..34923)
                     /gene="yvcK"
                     /locus_tag="IT892_000476"
     CDS             complement(34015..34923)
                     /gene="yvcK"
                     /locus_tag="IT892_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HAP3133719.1"
                     /translation="MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDN
                     GGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLK
                     ALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTP
                     IQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMV
                     YIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVL
                     EASDIPYRHDRQLLHNALEKALQALG"
     regulatory      35188..35332
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01055"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="molybdenum cofactor riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="molybdenum cofactor"
                     /db_xref="RFAM:RF01055"
     gene            35320..36309
                     /gene="moaA"
                     /locus_tag="IT892_000477"
     CDS             35320..36309
                     /gene="moaA"
                     /locus_tag="IT892_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HAP3133720.1"
                     /translation="MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNK
                     GFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNG
                     YRLERDVASWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVK
                     VNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELL
                     RRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLF
                     GEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG"
     gene            36331..36843
                     /gene="moaB"
                     /locus_tag="IT892_000478"
     CDS             36331..36843
                     /gene="moaB"
                     /locus_tag="IT892_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HAP3133721.1"
                     /translation="MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHV
                     VDKAIVKENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVEGF
                     GEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENIIAPQLDARTR
                     PCNFHPHLKK"
     gene            36846..37331
                     /gene="moaC"
                     /locus_tag="IT892_000479"
     CDS             36846..37331
                     /gene="moaC"
                     /locus_tag="IT892_000479"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HAP3133722.1"
                     /translation="MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMI
                     IDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETL
                     CRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEAD
                     D"
     gene            37324..37569
                     /gene="moaD"
                     /locus_tag="IT892_000480"
     CDS             37324..37569
                     /gene="moaD"
                     /locus_tag="IT892_000480"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase sulfur carrier subunit"
                     /protein_id="HAP3133723.1"
                     /translation="MIKVLFFAQVRELVGTDATEVAADFPTVEALRQHMAAQSDRWAL
                     ALEDGKLLAAVNQTLVSFDHPLTDGDEVAFFPPVTGG"
     gene            37571..38023
                     /gene="moaE"
                     /locus_tag="IT892_000481"
     CDS             37571..38023
                     /gene="moaE"
                     /locus_tag="IT892_000481"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HAP3133724.1"
                     /translation="MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLG
                     DSVNALTLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVTSA
                     HRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW"
     gene            38160..38864
                     /locus_tag="IT892_000482"
     CDS             38160..38864
                     /locus_tag="IT892_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAP3133725.1"
                     /translation="MDRFPRSDSIVQPRAGLQTYMAQVYGWMTVGLLLTAFVAWYAAN
                     SAAVMELLFTNRVFLIGLIIAQLALVIVLSAMIQKLSAGVTTMLFMLYSALTGLTLSS
                     IFIVYTAASIASTFVVTAGMFGAMSLYGYTTKRDLSGFGNMLFMALIGIVLASLVNFW
                     LKSEALMWAVTYIGVIVFVGLTAYDTQKLKNMGEQIDTRDTSNLRKYSILGALTLYLD
                     FINLFLMLLRIFGNRR"
     gene            39069..39782
                     /locus_tag="IT892_000483"
     CDS             39069..39782
                     /locus_tag="IT892_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAP3133726.1"
                     /translation="MESYSQNSNKLDFQHEARILNGIWLITALGLVATAGLAWGAKYL
                     EITATKYDSPPMYVAIGLLLLCMYGLSKDINKINAAIAGVIYLFLLSLVAIVVASLVP
                     VYAIIIVFSTAGAMFLISMLAGLLFNVDPGSHRFIIMMTLTGLALVIIVNAALMSERP
                     IWVISCLMIVLWSGIISHGRNKLLELAGKCHSEELWSPVRCAFTGALTLYYYFIGFFG
                     ILAAIAITLVWQRHTRFFH"
     gene            complement(39818..40774)
                     /locus_tag="IT892_000484"
     CDS             complement(39818..40774)
                     /locus_tag="IT892_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0104 family protein"
                     /protein_id="HAP3133727.1"
                     /translation="MSKSHPRWRLAKKILTWLFFIAVIVLLVVYAKKVDWEEVWKVIR
                     DYNRVALLSAVGLVVVSYLIYGCYDLLARFYCGHKLAKRQVMLVSFICYAFNLTLSTW
                     VGGIGMRYRLYSRLGLPGSTITRIFSLSITTNWLGYILLAGIIFTAGVVELPDHWYVD
                     QTTLRILGIGLLMIIAVYLWFCAFAKHRHMTIKGQKLVLPSWKFALAQMLISSVNWMV
                     MGAIIWLLLGQSVNYFFVLGVLLVSSIAGVIVHIPAGIGVLEAVFIALLAGEHTSKGT
                     IIAALLAYRVLYYFIPLLLALICYLLLESQAKKLRAKNEAAM"
     gene            complement(40774..42015)
                     /gene="clsB"
                     /locus_tag="IT892_000485"
     CDS             complement(40774..42015)
                     /gene="clsB"
                     /locus_tag="IT892_000485"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HAP3133728.1"
                     /translation="MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFE
                     DDVGKQLHAALLAAAQRGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLF
                     GMRTNVFRRMHRKIVVIDARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDIL
                     QFELENLPGQSAARRWWRRHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQ
                     ARREVIIANAYFFPGYRFLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVK
                     GGVQVFEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRD
                     NLNGIIAADCQQVDETMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPRLAQVDP
                     PAQPTMETQDRVETENTGVKP"
     gene            complement(42012..42773)
                     /locus_tag="IT892_000486"
     CDS             complement(42012..42773)
                     /locus_tag="IT892_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAP3133729.1"
                     /translation="MPDQTQQFSFKVLTINIHKGFTAFNRRFILPELRDAVRTVSADI
                     VCLQEVMGAHEVHPLHVENWPDTSHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRY
                     PIEHYENRDVSVDGAEKRGVLYCRIVPPMTGKAIHVMCVHLGLREAHRQAQLAMLAEW
                     VNELPDGEPVLVAGDFNDWRQKANHPLKVQAGLDEIFTRAHGRPARTFPVQFPLLRLD
                     RIYVKNASASAPTALPLRTWRHLSDHAPLSAEIHL"
     gene            42906..43316
                     /locus_tag="IT892_000487"
     CDS             42906..43316
                     /locus_tag="IT892_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133730.1"
                     /translation="MKWQQRVRVATGLSCWQIMLHLLVVALLVVGWMSKTLVHVGVGL
                     CALYCVTVVMMLVFQRHPEQRWREVADVLEELTTTWYFGAALIVLWLLSRVLENNFLL
                     AIAGLAILAGPAVVSLLAKDKKLHHLTSKHRVRR"
     gene            complement(43278..44384)
                     /locus_tag="IT892_000488"
     CDS             complement(43278..44384)
                     /locus_tag="IT892_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3133731.1"
                     /translation="MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLE
                     VTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFP
                     ADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
                     VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQI
                     FIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISS
                     LCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK
                     DASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM"
     gene            complement(44395..45528)
                     /locus_tag="IT892_000489"
     CDS             complement(44395..45528)
                     /locus_tag="IT892_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3133732.1"
                     /translation="MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFG
                     YGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRG
                     LVVIPVDFAEQMERANATAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
                     FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLS
                     TEITRTELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTL
                     GMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFV
                     STLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD"
     gene            complement(45521..47257)
                     /locus_tag="IT892_000490"
     CDS             complement(45521..47257)
                     /locus_tag="IT892_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415315.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP3133733.1"
                     /translation="MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGA
                     GKTTLMRMLAGLLKPDSGSATVIGFDPIKNDGALHAVLGYMPQKFGLYEDLTVMENLN
                     LYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
                     LLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQ
                     GGPKALTQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKEATPD
                     DIRHADGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKE
                     LTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMD
                     LKESSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGL
                     KSIASHATDELPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVE
                     KGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTMEQAFIQ
                     LIHDWDKEHSNE"
     gene            complement(47250..48248)
                     /gene="hlyD"
                     /locus_tag="IT892_000491"
     CDS             complement(47250..48248)
                     /gene="hlyD"
                     /locus_tag="IT892_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD"
                     /protein_id="HAP3133734.1"
                     /translation="MMKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRT
                     VNLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLML
                     AGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQA
                     TLKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTR
                     AVEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQ
                     IGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE"
     gene            complement(48248..48919)
                     /gene="cecR"
                     /locus_tag="IT892_000492"
     CDS             complement(48248..48919)
                     /gene="cecR"
                     /locus_tag="IT892_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415317.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CecR"
                     /protein_id="HAP3133735.1"
                     /translation="MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQN
                     IAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRA
                     CRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
                     NDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGL
                     SQRSL"
     gene            49148..50512
                     /gene="rhlE"
                     /locus_tag="IT892_000493"
     CDS             49148..50512
                     /gene="rhlE"
                     /locus_tag="IT892_000493"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="HAP3133736.1"
                     /translation="MSFDSLGLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMAS
                     AQTGTGKTAGFTLPLLQHLITRQPHAKGRRPVRALILTPTRELAAQIGENVRDYSKYL
                     NIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQVEILVLDEADR
                     MLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALAEKLLHNPLEIEVARRNTASD
                     QVTQHVHFVDKKRKRELLSHMIGKGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIH
                     GNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIG
                     RTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAIPGYEPDPSIKAEPIQNGRQ
                     QRGGGGRGQGGGRGQQQPRRGEGGAKSASAKPAEKPSRRLGDAKPAGEQQRRRRPRKP
                     AAAQ"
     gene            complement(50744..51226)
                     /gene="ybiA"
                     /locus_tag="IT892_000494"
     CDS             complement(50744..51226)
                     /gene="ybiA"
                     /locus_tag="IT892_000494"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-glycosidase YbiA"
                     /protein_id="HAP3133737.1"
                     /translation="MPVRAQRIQHVMQDTIINFYSTSDDYGDFSNFAAWPIKVDGKTW
                     PTSEHYFQAQKFLDEKYREEIRRVSSPMVAARMGRDRSKPLRKNWESVKEQVMRKALR
                     AKFEQHAELRALLLATAPAKLVEHTENDAYWGDGGHGKGKNRLGYLLMELREQLAIEK
                     "
     gene            51346..53496
                     /gene="dinG"
                     /locus_tag="IT892_000495"
     CDS             51346..53496
                     /gene="dinG"
                     /locus_tag="IT892_000495"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HAP3133738.1"
                     /translation="MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAG
                     EEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKK
                     IIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLK
                     GDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAE
                     VVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQL
                     DLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEH
                     RFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRA
                     LGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWR
                     SIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVE
                     PSIDNEEQHIAEMAAFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGD
                     QPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVI
                     TEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKR
                     LLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR"
     gene            53524..54486
                     /gene="ybiB"
                     /locus_tag="IT892_000496"
     CDS             53524..54486
                     /gene="ybiB"
                     /locus_tag="IT892_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
                     /protein_id="HAP3133739.1"
                     /translation="MDYRKIIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGG
                     VLIALRIKGEGEAEMLGFYEAMQNHTIKLTPPAGKPMPIVIPSYNGARKQANLTPLLA
                     ILLHKLGFPVVVHGVSEDPTRVLTETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGA
                     FCPPLEKQLAMRWRMGVRNSAHTLAKLATPFAEGEALRLSSVSHPEYIGRVAKFFSDI
                     GGRALLMHGTEGEVYANPQRCPQINLIDREGMRVLYEKQDTAGSELLPQAKDPETTAQ
                     WIERCLAGSEPIPESLKIQMACCLVATGEAATISDGLARVNQAF"
     gene            54627..55712
                     /locus_tag="IT892_000497"
     CDS             54627..55712
                     /locus_tag="IT892_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate/lactate/ureidoglycolate dehydrogenase"
                     /protein_id="HAP3133740.1"
                     /translation="MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAG
                     HDSHGIGMIPSYVRSWSQGHLQINHHAKTVKEAGAAVTLDGDRAFGQVAAHEAMALGI
                     EKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRF
                     GTNPFCVVFPRKDNFPLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPA
                     VMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTHQETLQTSPDAILNCMTTII
                     INPELFGAPDCNAQTEAFAEWVKASPHDDDKPILLPGEWEVNTRRERQKQGIPLDAGS
                     WQAICDAARQIGMPEETLQAFCQQLAS"
     gene            complement(55941..56201)
                     /locus_tag="IT892_000498"
     CDS             complement(55941..56201)
                     /locus_tag="IT892_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HAP3133741.1"
                     /translation="MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADG
                     ASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSGTAVIYK"
     gene            complement(56466..56732)
                     /gene="ybiI"
                     /locus_tag="IT892_000499"
     CDS             complement(56466..56732)
                     /gene="ybiI"
                     /locus_tag="IT892_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-type zinc finger protein YbiI"
                     /protein_id="HAP3133742.1"
                     /translation="MASGWANDDAVNEQINSTIEDAIARARGEIPRGESLDECEECGA
                     PIPQARREAIPGVRLCIHCQQEKDLQKPAYTGYNRRGSKDSQLR"
     gene            complement(56806..57483)
                     /gene="ybiX"
                     /locus_tag="IT892_000500"
     CDS             complement(56806..57483)
                     /gene="ybiX"
                     /locus_tag="IT892_000500"
                     /EC_number="1.14.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415325.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKHD-type hydroxylase YbiX"
                     /protein_id="HAP3133743.1"
                     /translation="MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQ
                     QVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVR
                     SHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCV
                     TPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGESEEILSLLNLYHNL
                     LREWSEI"
     gene            complement(57525..59807)
                     /locus_tag="IT892_000501"
     CDS             complement(57525..59807)
                     /locus_tag="IT892_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor Fiu"
                     /protein_id="HAP3133744.1"
                     /translation="MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTL
                     VVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVG
                     AFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
                     YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGE
                     KTHDAGRDKVKNERYGVAPSVAFGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSA
                     PSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVK
                     QDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGH
                     DVSTGVEFTRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYA
                     FDTLQITRDFELNGGIRLDNYHTEYDSATACGGSGRGAITCPTGVAKGSPVTTVDTAK
                     SGNLMNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKA
                     NTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNI
                     TPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGAR
                     YIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYVASINKS
                     GYRYHPGEPRTFLLTANMHF"
     gene            complement(60073..60333)
                     /locus_tag="IT892_000502"
     CDS             complement(60073..60333)
                     /locus_tag="IT892_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415327.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HAP3133745.1"
                     /translation="MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATG
                     ASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFGTATIYK"
     gene            60609..61535
                     /gene="rlmF"
                     /locus_tag="IT892_000503"
     CDS             60609..61535
                     /gene="rlmF"
                     /locus_tag="IT892_000503"
                     /EC_number="2.1.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415328.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(1618)-N(6))-methyltransferase
                     RlmF"
                     /protein_id="HAP3133746.1"
                     /translation="MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSV
                     DFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIP
                     ANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISSNPGLNRAIRLR
                     RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGG
                     QQQELWCEGGEVTFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVV
                     KKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR"
     gene            complement(61532..63757)
                     /gene="ybiO"
                     /locus_tag="IT892_000504"
     CDS             complement(61532..63757)
                     /gene="ybiO"
                     /locus_tag="IT892_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="HAP3133747.1"
                     /translation="MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQ
                     KKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEPVPKIVPPTLVEEQTVLQKVTEV
                     SRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL
                     PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRT
                     IAFQQSLFLNAFALIEFFKAVLRLIFCPNVAELRPFTIQDESARYWSRRLSWLSSLIG
                     YGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKEITQHLLNFAEHSLA
                     FFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSG
                     MFSRWLAKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFD
                     FWNWLQNGAGQKTVDILIRIALILFFSAVGWTVLASLIENRLASDIHGRPLPSARTRT
                     LLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGV
                     FIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGI
                     GSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLSNTAFTL
                     RVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQVLPAPGATPAEPLPPGEPT
                     L"
     gene            complement(64018..64740)
                     /gene="glnQ"
                     /locus_tag="IT892_000505"
     CDS             complement(64018..64740)
                     /gene="glnQ"
                     /locus_tag="IT892_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017491583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein
                     GlnQ"
                     /protein_id="HAP3133748.1"
                     /translation="MIEFKNVSKHFGPTQVLHNIDLNIAQGEVVVIIGPSGSGKSTLL
                     RCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGP
                     LRVRGANKEEAEKLARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
                     DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDG
                     NPQVLIKNPPSQRLQEFLQHVS"
     gene            complement(64737..65396)
                     /gene="glnP"
                     /locus_tag="IT892_000506"
     CDS             complement(64737..65396)
                     /gene="glnP"
                     /locus_tag="IT892_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015367581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease GlnP"
                     /protein_id="HAP3133749.1"
                     /translation="MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFAR
                     TFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSG
                     AYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
                     DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKI
                     L"
     gene            complement(65535..66281)
                     /gene="glnH"
                     /locus_tag="IT892_000507"
     CDS             complement(65535..66281)
                     /gene="glnH"
                     /locus_tag="IT892_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein GlnH"
                     /protein_id="HAP3133750.1"
                     /translation="MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGD
                     KYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAID
                     FSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
                     IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDEL
                     RDKVNGALKTLRENGTYNEIYKKWFGTEPK"
     gene            complement(66685..67188)
                     /gene="dps"
                     /locus_tag="IT892_000508"
                     /gene_synonym="pexB"
     CDS             complement(66685..67188)
                     /gene="dps"
                     /locus_tag="IT892_000508"
                     /gene_synonym="pexB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein Dps"
                     /protein_id="HAP3133751.1"
                     /translation="MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLS
                     LITKQAHWNMRGANFIAVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKT
                     PLKSYPLDIHNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLW
                     FIESNIE"
     gene            complement(67487..68374)
                     /gene="rhtA"
                     /locus_tag="IT892_000509"
     CDS             complement(67487..68374)
                     /gene="rhtA"
                     /locus_tag="IT892_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/homoserine exporter RhtA"
                     /protein_id="HAP3133752.1"
                     /translation="MPGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVT
                     ALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGVSLGGMNYLFYLSIQTVPLGIAVA
                     LEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACW
                     AIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGALQAGEALWHWSVIPLGLAVAILS
                     TALPYSLEMIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAAS
                     MGSTLTVRKESKIKELDIN"
     gene            68609..68674
                     /locus_tag="IT892_000510"
     CDS             68609..68674
                     /locus_tag="IT892_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133753.1"
                     /translation="METFCYMKWPVRHHKSRRVSH"
     gene            68727..69242
                     /gene="ompX"
                     /locus_tag="IT892_000511"
     CDS             68727..69242
                     /gene="ompX"
                     /locus_tag="IT892_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpX"
                     /protein_id="HAP3133754.1"
                     /translation="MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKM
                     GGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASI
                     YGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
                     GTWIAGVGYRF"
     gene            complement(69291..70874)
                     /locus_tag="IT892_000512"
     CDS             complement(69291..70874)
                     /locus_tag="IT892_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HAP3133755.1"
                     /translation="MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTA
                     AFTAILLLLWRTLPRVQKVLVGVSSLVAACYFPFAQAYGAPNFNTLLALHSTNMEEST
                     EILTIFPWYSYLVGLFIFALGVIAIRRKKENEKARWNTFDSLCLVFSVATFFVAPVQN
                     LAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQT
                     YVVVIGESARRDALGAFGGHWDNTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVD
                     GKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEVYFLKEGNFEADK
                     NTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTQGKYETFVQSKETSCYLY
                     TMTQTDDLLRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVP
                     FMVISSDDKAHRVIKARRSANDFLGFFSQWTGIKAKEINIKYPFISEKKAGPIYITNF
                     QLQKVDYNHLGTDIFDPKP"
     gene            complement(71146..71274)
                     /gene="mntS"
                     /locus_tag="IT892_000513"
     CDS             complement(71146..71274)
                     /gene="mntS"
                     /locus_tag="IT892_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganase accumulation protein MntS"
                     /protein_id="HAP3133756.1"
                     /translation="MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK"
     gene            71460..71927
                     /locus_tag="IT892_000514"
     CDS             71460..71927
                     /locus_tag="IT892_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MntR"
                     /protein_id="HAP3133757.1"
                     /translation="MSRRAGTPTAKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVEL
                     ISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLATMGLIEMIPWRGVFLTAEGEKLA
                     QESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK"
     gene            71924..73042
                     /locus_tag="IT892_000515"
     CDS             71924..73042
                     /locus_tag="IT892_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion transporter"
                     /protein_id="HAP3133758.1"
                     /translation="MSLPFLRTLQGDRFFQLLILVGIGLSFFVPFAPKSWPAAIDWHT
                     IITLSGLMLLTKGVELSGYFDVLGRKMVRRFATERRLAMFMVLAAALLSTFLTNDVAL
                     FIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLLTPIGNPQNILIWGRSGLSFAGFI
                     AQMAPLAGAMMLTLLLLCWCCFPGKAMQYHTGVQTPEWKPRLVWSCLGLYIVFLTALE
                     FKQELWGLVIVAAGFALLARRVVLSVDWTLLLVFMAMFIDVHLLTQLPALQGVLGNVS
                     HLSEPGLWLTAIGLSQVISNVPSTILLLNYVPPSLLLVWAVNVGGFGLLPGSLANLIA
                     LRMANDRRIWWRFHLYSIPMLLWAALVGYVLLVILPAN"
     gene            complement(73101..74021)
                     /gene="ldtB"
                     /locus_tag="IT892_000516"
     CDS             complement(73101..74021)
                     /gene="ldtB"
                     /locus_tag="IT892_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HAP3133759.1"
                     /translation="MNMKLKTLFAAAFAVVGFCSTASAVTYPLPTDGSRLVGQNQVIT
                     IPEGNTQPLEYFAAEYQMGLSNMMEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGIV
                     INSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAE
                     YRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNEDI
                     KFLFEKVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGQEIVPITLTKS
                     VQTVTGQPDVDQVVLDEAIKNRSGMPVRLN"
     gene            74240..75832
                     /locus_tag="IT892_000517"
     CDS             74240..75832
                     /locus_tag="IT892_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HAP3133760.1"
                     /translation="MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFM
                     KILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRI
                     YALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
                     KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMV
                     CTHMADLDYGELRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANA
                     SKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPL
                     FKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHE
                     YEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFG
                     KLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRILEI
                     TPERVIDFSGNYEDYLRSKGIE"
     gene            complement(76073..77338)
                     /locus_tag="IT892_000518"
     CDS             complement(76073..77338)
                     /locus_tag="IT892_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1479 domain-containing protein"
                     /protein_id="HAP3133761.1"
                     /translation="MASTFTSDTLPADHKAAIRQMKHALRAQLGDVQQIFNQLSDDIA
                     TRVAEINALKAQGDAVWPVLSYADIKAGHVTAEQREQIKRRGCAVIKGHFPREQALGW
                     DQSMLDYLDRNRFDEVYKGPGDNFFGTLSASRPEIYPIYWSQAQMQARQSEEMANAQS
                     FLNRLWTFESDGKQWFNPDVSVIYPDRIRRRPPGTTSKGLGAHTDSGALERWLLPAYQ
                     RVFANVFNGNLAQYDPWHAAHRTEVEEYTVDNTTKCSVFRTFQGWTALSDMLPGQGLL
                     HVVPIPEAMAYVLLRPLLDDVPEDELCGVAPGRVLPVSEQWHPLLIEALTSIPKLEAG
                     DSVWWHCDVIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYAHKVKAALEKGASPGDFP
                     REDYETNWEGRFTLADLNIHGKRALGMDV"
     gene            complement(77490..78305)
                     /gene="ybiV"
                     /locus_tag="IT892_000519"
     CDS             complement(77490..78305)
                     /gene="ybiV"
                     /locus_tag="IT892_000519"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase YbiV"
                     /protein_id="HAP3133762.1"
                     /translation="MSVKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIKFVVAS
                     GNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
                     NFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLNLPDEQIPL
                     VIDKLHVALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGN
                     DAEMLKMARYSFAMGNAAENIKQIARYATDDNNHEGALNVIQAVLDNTSPFNS"
     gene            complement(78451..80883)
                     /locus_tag="IT892_000520"
     CDS             complement(78451..80883)
                     /locus_tag="IT892_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HAP3133763.1"
                     /translation="MTTLKLDTLSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHL
                     DKPIPVRRALALAHHLANRTIWIKHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDL
                     ADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMT
                     SGDAHLAVNFPLLLEKGLDGLREKVAERRSRINLTVLEDLHGEQFLKAIDIVLVAVSE
                     HIERFAALAREMAATETRESRRDELLAMAENCDLIAHQPPQTFWQALQLCYFIQLILQ
                     IESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKLLEVNKIRSGSH
                     SKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGM
                     SNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKW
                     GYRCTGMSFINFARVMLAALEGGHDATSGKVFLPQEKALSAGNFNNFDEVMDAWDTQI
                     RYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGI
                     ANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDDDT
                     VDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRK
                     AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESDKQK
                     LMILLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVAGYSAFFTALSPDA
                     QDDIIARTEHML"
     gene            complement(80889..81788)
                     /locus_tag="IT892_000521"
     CDS             complement(80889..81788)
                     /locus_tag="IT892_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415345.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HAP3133764.1"
                     /translation="MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARTQDL
                     LYDARLCLEGCELCAKAAPEVIERALNGLLIHREKLTPEHLTALTDCCPTQALTVCGE
                     VKSVEEIMTTVLRDKPFYDRSGGGLTLSGGEPFMQPEMAMALLQASHEAGIHTAVETC
                     LHVPWKYIAPSLPYIDLFLADLKHVADAPFKQWTDGNAARVLDNLKKLAAAGKKIIIR
                     VPLIQGFNADETSVKAITDFAADELHVGEIHFLPYHTLGINKYHLLNLPYDAPEKPLD
                     APELLDFAQQYACQKGLTATLRG"
     gene            81919..82581
                     /gene="fsa"
                     /locus_tag="IT892_000522"
     CDS             81919..82581
                     /gene="fsa"
                     /locus_tag="IT892_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415346.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAP3133765.1"
                     /translation="MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAAGKKPLDVVLP
                     QLHEAMGGQGRLFAQVMATTAEGMVNDALKLRSIIADIVVKVPVTAEGLAAIKMLKAE
                     GIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPQA
                     KVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVDAAVAKFEQDWQGAFGRT
                     SI"
     gene            complement(82657..83406)
                     /gene="moeB"
                     /locus_tag="IT892_000523"
     CDS             complement(82657..83406)
                     /gene="moeB"
                     /locus_tag="IT892_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HAP3133766.1"
                     /translation="MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLIVGLGGLGC
                     AASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPHIA
                     ITPVNALLDDAELAALIAEHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQ
                     ITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKMLAGYGKP
                     ASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ"
     gene            complement(83406..84641)
                     /gene="moeA"
                     /locus_tag="IT892_000524"
     CDS             complement(83406..84641)
                     /gene="moeA"
                     /locus_tag="IT892_000524"
                     /EC_number="2.10.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HAP3133767.1"
                     /translation="MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDV
                     VSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGA
                     PVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAE
                     LPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGC
                     EVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKL
                     AIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVR
                     TASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGN
                     VEVGEWVEVEPFNALFGGL"
     gene            84845..85810
                     /gene="iaaA"
                     /locus_tag="IT892_000525"
     CDS             84845..85810
                     /gene="iaaA"
                     /locus_tag="IT892_000525"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAP3133768.1"
                     /translation="MGKAVIAIHGGAGAISRAQMSLQQELRYIEALSAIVETGQKMLE
                     AGESALDVVTEAVRLLEECPLFNAGIGAVFTRDETHELDACVMDGNTLKAGAVAGVSH
                     LRNPVLAARLVMEQSPHVMMIGEGAENFAFARGMERVSPEIFSTPLRYEQLLAARKEG
                     ATVLDHSGAPLDEKQKMGTVGAVALDLDGNLAAATSTGGMTNKLPGRVGDSPLVGAGC
                     YANNASVAVSCTGTGEVFIRALAAYDIAALMDYGGLSLAEACERVVMEKLPALGGSGG
                     LIAIDHEGNVALPFNTEGMYRAWGYAGDTPTTGIYREKGDTVATQ"
     gene            85797..>86679
                     /locus_tag="IT892_000526"
     CDS             85797..>86679
                     /locus_tag="IT892_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP3133769.1"
                     /translation="MPHSDELDAGNVLAVENLNIAFMQDQQKIAAVRNLSFSLQRGET
                     LAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLQRRSREVIELSEQNAAQMRHVR
                     GADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQT
                     ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEM
                     SMGVIFITHDMGVVAEIADRVLVMYQGEAVETGTVEQIFHAPQHPYTRALLAAVPQLG
                     AMKGLDYPRRFPLISLEH"
BASE COUNT        20665 a        21998 c        23095 g        20921 t
ORIGIN      
        1 gagttgagcg cagcgaaaca acggagccgc tcgcggcgac ggcccgaagg gcgagcgaag
       61 cgagtcatcc tgcacgaccc accaatgtaa aaaagcgccc taaaggcgct tttttgctat
      121 tcaggcatcc tcaatttcac tttgtaaacc tgatgacatc gtcagagctt actgtgcaag
      181 caactctatg tcggtggaat taggcgtaaa atgacgcatc ctgcacatta ggcgtaattc
      241 gagtgacttt tccccaccat tcgactatct tgtttagcat ataaaacaaa ttacaccgat
      301 aacagcgaat attacgctaa tgtcggtttt aacgttaagc ttgtaaaacg agatggtaag
      361 atgagcgtaa tgtttgatcc agacacggcg atttatcctt tccccccgaa gccgacgccg
      421 ttaagcattg atgaaaaagc gtattaccgc gagaagataa aacgtctgct aaaagaacgt
      481 aatgcggtga tggttgccca ctactatacc gatcccgaaa ttcaacaact ggcagaagaa
      541 accggtggct gtatttctga ttctctggaa atggcgcgct tcggtgcaaa gcatcccgct
      601 tctactttgt tagtcgctgg ggtgagattt atgggagaaa ccgccaaaat tctcagtccg
      661 gaaaaaacaa ttctgatgcc gacacttcag gctgaatgtt cactggatct cggctgccct
      721 gttgaagaat ttaacgcatt ttgcgatgcc catcccgatc gtactgtcgt cgtctacgcc
      781 aacacttctg ctgcggtaaa agcgcgcgca gattgggtgg taacttcaag cattgccgtc
      841 gaacttattg atcatcttga tagtttgggt gaaaaaatca tctgggcacc cgacaaacat
      901 ctggggcgtt acgtgcaaaa acagacgggt ggagacattc tatgctggca gggtgcctgt
      961 attgtgcatg atgaatttaa gactcaggcg ttaacccgct tgcaagaaga atacccggat
     1021 gctgccatac tggtgcatcc agaatcacca caagctattg tcgatatggc ggatgcggtc
     1081 ggttccacca gtcaactgat cgctgctgcg aaaacattgc cacatcagag gcttattgtg
     1141 gcaaccgatc ggggtatttt ctacaaaatg cagcaggcgg tgccagataa agagttactg
     1201 gaagcaccaa ccgcaggtga gggtgcaacc tgccgcagct gcgcgcattg tccgtggatg
     1261 gccatgaatg gccttcaggc catcgcagag gcattagaac aggaaggaag caatcacgag
     1321 gttcatgttg atgaaaggct gcgagagagg gcgctggtgc cgctcaatcg tatgctggat
     1381 tttgcggcta cactacgtgg ataacgaata ataaggcgta acgttacgct ttgggggaaa
     1441 gatggatttt tttagtgtgc agaatatcct ggtacatata ccaatagggg caggcggtta
     1501 tgatctctca tggatcgaag cggtaggcac gatcgccggg ttgctgtgta ttggccttgc
     1561 cagtctggag aagatcagca actacttctt tggcctgatc aacgtcacct tgtttggcat
     1621 tattttcttt cagattcagc tgtatgccag cctgctatta caggtgtttt tctttgccgc
     1681 gaatatttac ggttggtatg cgtggtcgcg acaaaccagt cagaacgagg cggagttgaa
     1741 aattcgctgg ttgccattgc cgaaggcact cagctggttg gcggtttgcg ttgtttcgat
     1801 tggtctgatg acggtattta tcaatccggt gtttgcattt ttgacccgcg tggcagtcat
     1861 gatcatgcaa gcattaggat tacaggttgt gatgcctgaa ctgcaaccgg acgctttccc
     1921 gttctgggat tcatgcatga tggtgttatc tatcgtggca atgattctga tgacgcgtaa
     1981 gtatgtggaa aactggctgt tgtgggtgat tattaacgtg attagcgtcg ttatttttgc
     2041 acttcagggc gtttacgcca tgtctctgga gtacatcatc ctgaccttta ttgcgctcaa
     2101 cggcagccgg atgtggatca acagcgcacg tgaaagaggc tcacgcgcgc tgtcccatta
     2161 atggtgatga tgtgaatggc cagacacccc ttcattcagg tggcagtctg gcccatgaca
     2221 aggttgatat tccatctgaa tggtggcgtg ctcaatctga tagtgatcca tcaggtagtg
     2281 ttggatctga tccaacaagg catcgtgatc gtgtggcggg atcacctgca catgcaacgt
     2341 catcaccggc ttctcgccta ccatccatac atgtacatgg tgcacattgc ggacttccgg
     2401 gatttcccgg cacatacgac gcttcagttc agcgatatcc agcgataccg gtgcaccttc
     2461 aagtaattca ttcacgctat ctttcaacag tcgccacgcg ctacgcagaa ccagaagcga
     2521 caccagtatc gagagaatgg ggtcagcagg tgtccagcca gtccagataa taatcaacgc
     2581 ggcaataata gccccaaccg aacccagcag gtccccgagc acatgcagtg ccgctgctcg
     2641 tacgttgagg tttttctctt cgctgccgtg atgaagtaac cagaaagaaa gtatatttgc
     2701 cagcaaccca gccacggcaa ttgccatcat catgccgccc tcgaccggac gcggcgtgcg
     2761 gaagcgttct atcgcctccc agacaatcaa aatggtaatt accacgaggg ctatggcatt
     2821 cacaaacgcc gcgagcgtgg tcagtcttag ccaaccgaaa gtgtggcgaa tggtgggagg
     2881 acgacgtgaa aattgcacgg cgagtagggc gaaaagcagg gcggcagtat cggtcaacat
     2941 atgacccgca tcggccagca atgccagaga accagaaaga aaaccaccaa cgacttctac
     3001 cagcataaac ccggcagtca cgccgaaagc atacaacaag cgacgagcat tattatcttc
     3061 tggcaggtgt gaggacgtgt gtgagtgtga gtgcgccatg acgagtcatc ccttaattat
     3121 tctcacttaa ctttatgaca tcatactgct tttagaagtg aaaaattaaa agggagagac
     3181 tccgctctcc cattattggc tattttgcag ggttactgcg tggtaccgtc ggttttggta
     3241 tcgacatcat tattgatgcc atcaccggtt tgtacctttt tattgatatc cggacagcga
     3301 ccatctttgc acatggtgtt cttgtgctct tcatctttgg tcattccgtc attgttcatt
     3361 gaagaaccat ccgaatgcag cattgtgccg ccagaaccgg tatttacccc gttattgtcg
     3421 acgttatttg gcgcgacatt ttcacgggcg tcaggggcta cctggcccgc atcagctgcg
     3481 gcgtttgcct ggccgttatt agtttgcgct ccgctatcgg cagccagtgc ggcaccgctg
     3541 gcaaggctta gagtggcagt cagaaataat gtggccagtt ttgtcatttt cataggatgc
     3601 tcctgttatg gtcgttatgt cggataacct cttccaacag tgcatttgca ggtgaatata
     3661 aggcattggt ttaagatttc agccaggtta tgaaacgcag cagagaatct tgaaataatt
     3721 aacaaacaaa ggagttacag ttagaaattg taggagagat ctcgtttttc gcgacaatct
     3781 ggcgtttttc ttgctaattc caggattaat ccgttcatag tgtaaaaccc cgtttacaca
     3841 ttctgacgga agatatagat tggaagtatt gcattcacta agataagtat ggcaacactg
     3901 gaacagacat gaattatcag aacgacgatt tacgcatcaa agaaatcaaa gagttacttc
     3961 ctcctgtcgc attgctggaa aaattccccg ctactgaaaa tgccgcgaat acggttgccc
     4021 atgcccgaaa agcgatccat aagatcctga aaggtaatga tgatcgcctg ttggttgtga
     4081 ttggcccatg ctcaattcat gatcctgtcg cggcaaaaga gtatgccact cgcttgctgg
     4141 cgctgcgtga agagctgaaa gatgagctgg aaatcgtaat gcgcgtctat tttgaaaagc
     4201 cgcgtaccac ggtgggctgg aaagggctga ttaacgatcc gcatatggat aatagcttcc
     4261 agatcaacga cggtctgcgt atagcccgta aattgctgct tgatattaac gacagcggtc
     4321 tgccagcggc aggtgagttt ctcgatatga tcaccccaca atatctcgct gacctgatga
     4381 gctggggcgc aattggcgca cgtaccaccg aatcgcaggt gcaccgcgaa ctggcatcag
     4441 ggctttcttg tccggtcggc ttcaaaaatg gcaccgacgg tacgattaaa gtggctatcg
     4501 atgccattaa tgccgccggt gcgccgcact gcttcctgtc cgtaacgaaa tgggggcatt
     4561 cggcgattgt gaataccagc ggtaacggcg attgccatat cattctgcgc ggcggtaaag
     4621 agcctaacta cagcgcgaag cacgttgctg aagtgaaaga agggctgaac aaagcaggcc
     4681 tgccagcaca ggtgatgatc gatttcagcc atgctaactc gtccaaacaa ttcaaaaagc
     4741 agatggatgt ttgtgctgac gtttgccagc agattgccgg tggcgaaaag gccattattg
     4801 gcgtgatggt ggaaagccat ctggtggaag gcaatcagag cctcgagagc ggggagccgc
     4861 tggcctacgg taagagcatc accgatgcct gcatcggctg ggaagatacc gatgctctgt
     4921 tacgtcaact ggcgaatgca gtaaaagcgc gtcgcgggta aggtttaatt gtcggatgcg
     4981 ccgtcagagt ggcgtatccg atgaatcacc acaggcctga taagtcgcgc agcgtcgcat
     5041 caggcaatgt gctccattgt tagcaacaaa aaagccgact cacttgcagt cggctttctc
     5101 attttaaacg aatgacgttt acttcgcttt accctggttt gcaaccgccg ctgctttcgc
     5161 tgcgatctcg tcagcattac ccagataata gcgtttcagc ggtttgaaat tctcgtcgaa
     5221 ctcatacacc agcggcacgc cagtcgggat attaagctca agaatctctt cttcgctcat
     5281 gttatcaaga tatttcacca gcgcacgtaa agagttaccg tgtgcagcga tgatcacgcg
     5341 ctcaccgctc ttcatacgcg gcagaatagt ttcattccag taagggatca cgcggtcaat
     5401 ggtcagcgcc aggctttccg tcagcggcag ttctttctcg ctcagtttcg cgtaacgcgg
     5461 atcgtgaccc ggataacgct catcatcttt agtcagttcc ggcggagtca ctgcaaaacc
     5521 acgacgccac tgtttcacct gctcgtcgcc atacttttca gcagtttccg ctttgttcag
     5581 accctgcaac gcaccgtagt gacgttcgtt cagtttccag gatttctcaa cgggcagcca
     5641 tgcctgatcc agttcgtcca gcacattcca cagggtatgg atagcgcgtt tcagcacaga
     5701 agtgtaagca aagtcaaagc tgtaaccttc ctctttcagc agcttacctg ctgcttttgc
     5761 ttcgcttacg cctttctcag acagatccac gtcgtaccaa ccggtgaaac ggttttcttt
     5821 gttccactga ctttcgccat gacgaaccag aaccagctta gttacagcca tatacttact
     5881 cctcaaatca tcttttaatg ataataattc tcattatatt gccgcgacga agcaacagca
     5941 atgcttacgc ataaccatag cgaaaatagt ggcgcagtgt aaggttgttg tgaatattga
     6001 gttgcaaata tgtcggtgtt tgctggtgat ttgaacaata tgagataaag ccctcatgac
     6061 gagggcgtaa cattactcag caataaactg atattccgtc aggctggaat actcttcgcc
     6121 aggacgcagg aagcagtccg gttgcggcca ttcagggtgg ttcgggctgt ccggtagaaa
     6181 ctcgctttcc agagccagcc cttgccagtc ggcgtaaggt tcggttcccc gcgacggtgt
     6241 gccgccgagg aagttgccgg agtagaattg cagagccgga gcggtggtgt agaccttcag
     6301 ctgcaatttt tcatctgctg accagacatg cgccgccact ttcttgccat cgcctttggc
     6361 ctgtaacaag aatgcgtgat cgtaaccttt cactttgcgc tgatcgtcgt cggcaagaaa
     6421 ctcactggcg atgattttgg cgctgcggaa atcaaaagac gttccggcga cagatttcag
     6481 gccgtcgtgc ggaatgccgc cttcatcaac cggcagatat tcgtccgcca gaatctgcaa
     6541 cttgtgattg cgcacgtcag actgctcgcc gtcaagattg aaatagacgt gattagtcat
     6601 attcaccggg caaggtttat caactgtggc gcgataagta atggagatac ggttatcgtc
     6661 ggtcagacga tattgcaccg tcgcgccgag attacccggg aagccctgat caccatcatc
     6721 tgaactcagg gcaaacagca cctgacgatc gttctggttc acaatctgcc agcgacgttt
     6781 gtcgaaccct tccggcccgc cgtgcagctg gttaacgccc tgacttggcg aaagcgtcac
     6841 ggtttcaccg tcaaaggtat aacggctatt ggcgatacgg ttggcataac gaccaataga
     6901 ggcccccaga aacgcggcct gatcctgata gcattccggg ctggcacagc cgagcagcgc
     6961 ctcgcggacg ctgccatcgg aaagcggaat acgggcggaa agtaaagtcg caccccagtc
     7021 catcagcgtg actaccatcc ctgcgttgtt acgcaaagtt aacagtcggt acggctgacc
     7081 atcgggtgcc agtgcgggag tttcgttcag cactgtcctg ctccttgtga tggtttacaa
     7141 acgtaaaaag tctctttaat acctgttttt gcttcatatt gttcagcgac agcttgctgt
     7201 acggcaggca ccagctcttc cgggatcagc gcgacgatac agccgccaaa tccgccgccg
     7261 gtcatgcgta cgccaccttt gtcgccaatc acagctttga cgatttctac cagagtgtca
     7321 atttgcggca cggtgatttc gaaatcatcg cgcatagagg catgagactc cgccatcaac
     7381 tcgcccatac gtttcaggtc gccttgctcc agcgcgctgg cagcttcaac ggtgcgggcg
     7441 ttttcagtca gtatatgacg cacgcgtttt gccacgatcg ggtccagttc atgcgcaaca
     7501 gcgttgaact cttcaatggt gacatcacgc agggctggct gctggaagaa acgcgcaccg
     7561 gtttcgcact gttcacgacg ggtgttgtat tcgctgccaa ccagggtacg tttgaagtta
     7621 ctgttgatga tgacgacagc cacacctttg ggcatggaaa ctgctttggt ccccagtgag
     7681 cggcaatcga tcagcaaggc atgatctttc ttgccgagcg cggaaattag ctgatccatg
     7741 atcccgcagt tacagcctac aaactggttt tctgcttcct gaccgttaag cgcgatttgt
     7801 gcgccgtcca gcggcagatg ataaagctgc tgcaatacgg ttccgaccgc gacttccagt
     7861 gaagcggaag aacttaaccc ggcaccctgc ggcacattgc cgctgatcac catgtccacg
     7921 ccgccgaagc tgttgttacg cagttgcaga tgtttcacca cgccacgaac gtagttagcc
     7981 cattgatagt tttcatgtgc gacaatgggc gcatcgaggg aaaactcgtc gagctgattt
     8041 tcataatcgg ctgccatcac gcgaacttta cggtcatcgc gtggtgcaca actgatcacg
     8101 gtttgataat caatcgcgca gggcagaacg aaaccgtcgt tgtagtcggt gtgttcacca
     8161 atcaaattca cgcggccagg cgcctgaatg gtgtgagtgg cagggtagcc aaatgcgttg
     8221 gcaaacagag attgtgtttt ttctttcaga ctcatttctt acactccgga ttcgcgaaaa
     8281 tggatatcgc tgactgcgcg caaacgctct gctgcctgtt ctgcggtcag gtctcgctgg
     8341 gtctctgcca gcatttcata accaaccata aatttacgta cggtggcgga gcgcagcaga
     8401 ggcggataaa agtgcgcgtg cagctgccag tgttgattct cttcgccatt aaatggcgcg
     8461 ccgtgccagc ccatagagta ggggaaggag cactggaaga ggttgtcata acgactggtc
     8521 agctttttca acgccagcgc cagatcgctg cgctgggcgt cggtcaaatc ggtgatccgt
     8581 aaaacgtggg ctttgggcag cagtagcgtt tcgaacggcc aggcagccca gtaaggcacg
     8641 acggctaacc agtgttcggt ttcgacaacg gtacggctac cgtctgccag ctcgcgctga
     8701 acataatcca ccagcattgg tgatttctgt tcggcaaaat attctttttg caggcggtct
     8761 tcgcgctcag cttcgttagg caggaagcta tttgcccaaa tctgaccgtg cggatgcggg
     8821 ttagagcagc ccatcgccgc gcctttgttt tcaaaaacct gcacccatgg gtacgttttc
     8881 cccagttctg cggtttgctc ctgccaggtt ttgacgattt ccgtcaatgc tgcaacgctg
     8941 agctctggca gcgttttact gtgatccggt gaaaagcaga tcacccggct ggtgccgcgc
     9001 gcgctctggc aacgcatcag cggatcgtga ctttctggcg catctggcgt gtcagacatc
     9061 aaagccgcaa agtcattagt gaaaacgtaa gtcccggtgt aatcggggtt tttatcgcct
     9121 gtcacccgca cattacctgc gcagaggaag caatctggat cgtgcgcagg taacacctgt
     9181 ttggctggcg tttcctgcgc cccctgccag gggcgcttag cgcggtgcgg tgaaaccaga
     9241 atccattgcc cggtgagcgg gttgtagcgg cgatgtggat gatcaacggg attaaattgc
     9301 gtcatggtcg ttccttaatc gggatatccc tgtggatggc gtgactgcca gtgccaggtg
     9361 tcctgcgcca tttcatcgag tgtgcgcgtt acgcgccagt tcagttcacg gtcggctttg
     9421 ctggcgtccg cccagtaggc cggaaggtcg ccctcgcgac gcggtgcaaa atgataatta
     9481 accggtttgc cgcaggcttt gctgaaggca ttaaccacgt ccagcacgct gttgcctacg
     9541 ccagcgccga ggttgtagat gtgtacgcct ggcttgttcg ccagtttttc catcgccacg
     9601 acgtgaccgt ccgccagatc cattacgtgg atgtaatcgc gtacgccagt accatcttcg
     9661 gtcggataat cgttaccaaa aatcgccagc gagtcgcgac ggcctacagc aacctgggcg
     9721 atgtatggca tcaggttatt cggaatgcct tgcggatctt cgcccatatc gcccgacgga
     9781 tgcgcgccaa ccgggttgaa gtagcgcagc agggcaatgc tccagtccgg ctgggctttt
     9841 tgcagatcgg tgaggatctg ttccaccatc agcttgcttt tgccgtaagg gctttgcggt
     9901 gtgccggtcg ggaagctttc aacgtatgga attttgggct gatcgccata aacggtggcg
     9961 gaggagctaa aaataaagtt tttgacgtta gcggcgcgca tggcgctaat caggcgcaga
    10021 gtgccgttga cattgttgtc gtaatattcc agcggttttt gtaccgattc gcccacggct
    10081 ttcagcccgg cgaagtggat cacggtgtcg atagcgtgat cgtgcaggat ctcggtcatc
    10141 aacgcttcgt tacgaatatc gccttcaaca aacgttggat gtttgccgcc taaacgctcg
    10201 ataacaggca gtacgctgcg cttactgtta cagaggttat caagaatgat gacatcatga
    10261 ccgttttgca gtaattgcac acaggtatga cttccaatgt aaccgctacc accggtaacc
    10321 agaactctca taattcgctc cattaggctt atggtatgaa ataaccatag cataacaaag
    10381 atgcgaaaag tgtgacatgg aataaattag tggaatcgtt tacacaagaa tttagccgtt
    10441 ttttatgcgc gattaagtga ttataaaaca gagggtttat gaatgattgc gctttttatc
    10501 tgaaaaaaga cgcggtttca tgcctgcatg cgtcgaaccg ttggccggag agggcgctaa
    10561 ggccgcctcc ggcaaggtca gcactaccga ctcaatatat ttttgtcagc acatagcgat
    10621 agagtccacc gtccggcacg aactcaagac gatgggtaat acaggcaggc gcatcttcag
    10681 cgtggtgcga aacaaacaac aattgcgttt caccttcgct aatcagcaca tcaacaaaac
    10741 ggcggataag ctggcgattc agcggatcaa gcccctgtag tggttcatcg agaataagca
    10801 acgtcggatg tttcaccagt gcgcggacaa tcagcgccag acgctgctgt ccccaggaaa
    10861 gactatggaa cggagcgtca gccgtgcgtt tatcaatgcc gagaatatcc agccactgct
    10921 gcaccagttt ttgctggcga tccgaaacgg cctgataaat gccaatcgaa tcaaaatagc
    10981 cagaaagaat cacattacgc acggtagtgc tgacccggta atccagatgc aaactactgc
    11041 tgacgtaacc gatatgcttt ttgatatccc agatggtttc gccgctgccg cgacgtcgtc
    11101 cgaaaagcgt caaatcgttg ctgtaacctt gcggatgatc gccagtaacc aggcttaata
    11161 acgtcgattt tcctgcacca tttggcccga caatttgcca gtgttcgcct ggattcacct
    11221 gccagctaag gttattaaga atggggcgat cgttataaga aaccacgcca ttgttcagca
    11281 caatgcgcgg ttcgttggcg ggtaaggcgt gacgtgctga aggttcatcc ggctccggca
    11341 gttgcacacc ttcaagctgt tcactatgcg ccagttgcgc gacgagtgct tgttggagca
    11401 gttcctcttt agcgccagtt tccgctaacg tgcaatccgc cagcacgcca gcaaactgga
    11461 caaactccgg gatctcatcg aagcgattga gcaccagtac cagagtaata ccggactgat
    11521 gtaacgaggc gagtcgctca gccagctgct gacgtgaggc aacatccagg ccatcgaacg
    11581 gctcatcaag aatcaacaag tcaggctccg acatcagcgc ctgacacagc agggtttttc
    11641 gcgtctcgcc agtggaaagg tatttaaagc gtcggtcgag gagggcggta ataccgaact
    11701 gctgcgccag ttgcatgcaa cgcggtgcat cctttacttc atcctgaatg atctcagccg
    11761 tagtgcgtcc ggtgtcatct tcgccagggc cgagcatatc ggtgttattc cgctgccatt
    11821 cgtcgctgac gagtttttgc aattgctcga aggagagacg agtgatgtgg gaaaactggc
    11881 tttgccgttc acctttcaaa agcggaagtt cccccgccag cgcgcgggcc agggccgatt
    11941 tcccgcttcc attcgaaccg acaaacgccc aactatcacc cgcgtttaac gttagctgag
    12001 gcaattgcag cgtttttgtg tcgctaagac gaaacgtgcc ttgcaaaatt tgcaacgatg
    12061 acattttata tcccactttg tgcagcgatt actgacaggg atacgtgttt cataacaaat
    12121 tgtcaacacg cttagcacag cgtggcgata atcacgctgt cggcattaaa gtaggccgtg
    12181 acattctgtc cttgctgaag agaagtcgct tcatttaccg gcactgtggc gcacagtgtt
    12241 tgcccgtcgg gtagcgccat taatacttcg cactgctctg cgccgcgctc aatatgacta
    12301 ataatacccg gtaattggtt gtcagcgttt tgcgcgaccg cctcgtcctg agtaatacct
    12361 acccacggcg cttttagcaa tatcaacact tctttgcctt catccagccc cagacgcgcg
    12421 ccgctttgtg cggtaattgc gactttcagg cgtgtttttc cgtcagccag taagacatca
    12481 acatgctgtt gaacgtcatc atgatcgcgg gcggtgatgg taccgaacca ctggttacgg
    12541 gcgctggttt gcagtgaaaa acgtgagatc gcggccagca ggctgttcag cggcagggcg
    12601 tcatcgtcac ttaacacatc aaaggctttt tgctggattt gcgccagtaa gtcatagagc
    12661 tgaatcagtc gctgaccata gcgggtcagt actgcgccgc cgccaccttt accgcctgtt
    12721 gcgcgctcga ccagaatatg ctcacttaac tgattcatct cgttaatggc atcccaggcg
    12781 cttttatagc taataccggc atctttcgct ccctggctaa tggaaccgga aagcgcaatg
    12841 tgttttagta gcgaaatgcg gcgcgggtcg gcgaataatt tttgttggag cttaagggtg
    12901 agaaggattt cggcctgcat aacaatgtcc tggcaaaagt cttattgtga cggaaaacga
    12961 gcgccacgca aagctgaccg cacaaaaggg gagtgctttt ctgtgcttag cggttagaat
    13021 agtctcatga ctatatctgg agttgaccat gttagagtta ttaaaaagtc tggtattcgc
    13081 cgtaatcatg gtacctgtcg tgatggccat catcctgggt ctgatttacg gtcttggtga
    13141 agtattcaac atcttttctg gtgttggtaa aaaagaccag cccggacaaa atcattgatt
    13201 ccctgaatgc ccgcttagtc gggcattttc tttttctcaa cttcctgctt ttcctgccga
    13261 tattttttct tatctacctc acaaaggtta gcaataactg ctgggaaaat tccgagttag
    13321 tcgttatatt gtcgcctaca taacgttaca ttaaggggtt accaatggct cgtaaatggt
    13381 tgaacttgtt tgccggggcg gcactctctt tcgctgttgc tggcaatgca ctggcagatg
    13441 aagggaaaat cacggtgttc gccgccgcat cactgactaa cgcaatgcag gacattgcta
    13501 cgcagtttaa aaaagagaaa ggcgtggatg tggtttcttc tttcgcttcg tcatctactc
    13561 tcgcccgtca gattgaagcg ggtgcgcctg cggatctgtt tatttctgcc gatcagaaat
    13621 ggatggatta tgcggttgat aaaaaagcga tcgatacagc tacgcgtcag acactgctcg
    13681 gcaatagcct ggtcgttgta gcaccgaaag ccagcgtgca gaaagatttc accatcgaca
    13741 gcaaaaccaa ctggacttca ctgctgaatg gcggtcgcct ggcggttggc gatccggaac
    13801 atgttcccgc tggcatttat gcaaaagaag cactgcaaaa actgggcgca tgggatacgc
    13861 tctctccgaa actggcccca gcggaagatg ttcgtggggc gctggcgctg gtcgaacgta
    13921 acgaagcgcc tctgggcatt gtctacggtt ctgacgcagt tgccagcaaa gggataaaag
    13981 tggttgccac cttcccggaa gattcacata aaaaagtgga atatccggtt gctgttgtgg
    14041 aagggcataa caatgcgaca gtgaaagcat tttatgatta tctgaaggga ccgcaggcag
    14101 cggaaatctt taaacgttac ggatttacaa tcaagtaatg atactgaccg atccagaatg
    14161 gcaggcagtt ttattaagcc tgaaagtttc ttccctggct gtgctgttta gcctgccgtt
    14221 tgggatcttt tttgcctggt tactggtgcg ttgcacgttt ccgggcaaag ctctgctcga
    14281 cagcgtactg catctaccgc tggtgttacc gcccgtggtc gtcggttact tattattagt
    14341 ttcgatggga cggcgcggat ttatcggtga acgtctgtat gactggtttg gtattacctt
    14401 cgcctttagc tggcgcggcg cggttctcgc tgccgccgtc atgtcgtttc cgctgatggt
    14461 gcgggcaatt cgtctggcgc tggaaggggt tgatgtcaaa ctggaacagg ccgcaagaac
    14521 actgggggcc gggcgctggc gcgttttctt tactatcacg ttaccgctga ccttaccggg
    14581 aattattgtt ggtacggtac tggcttttgc tcgttctctc ggtgagtttg gtgcaaccat
    14641 cacctttgtg tcgaacattc ctggtgaaac gcgaaccatt ccttctgcca tgtataccct
    14701 gatccagacc cccggcgggg aaagtggagc ggcgagactg tgcattattt ctattgcgct
    14761 ggcgatgatc tccctgttga tttcagaatg gctggccaga atcagccgtg aacgggcggg
    14821 gcgctaatca tgctggaact gaatttttcc cagacgttgg gcaaccattg cctgactatt
    14881 aatgaaacgc tgcccgccaa tggcatcact gctatctttg gcgtctccgg tgccggaaaa
    14941 acttcgctga ttaacgccat cagtggactg acgcgcccgc aaaaagggcg gattgtcctc
    15001 aatgggcggg tactaaatga tgccgaaaaa ggtatctgcc tgacgccgga aaagcgtcgc
    15061 gttggctatg tttttcagga tgcgcggctg ttcccgcatt acaaagtgcg tggcaatctg
    15121 cgctacggca tgtcgaaaag tatggtcgat cagtttgata agctggtggc gcttttaggc
    15181 attgaaccgt tgcttgaccg tttaccaggc agcctgtccg gaggcgaaaa acagcgcgtg
    15241 gcgattggtc gggctttgct gacagcaccg gaattgctgt tgctggatga accgctggcg
    15301 tcactggata ttccgcgtaa acgcgaactg ttgccttatc tgcaacggct gacacgggaa
    15361 atcaacattc cgatgttgta tgtcagccat tcgctggatg agatcctcca tctggcagac
    15421 agagtgatgg tactggaaaa cggtcaggtg aaagcctttg gcgcgctgga ggaagtgtgg
    15481 ggcagtagcg tgatgaatcc gtggctgccg aaagagcaac aaagtagcat tctgaaagtg
    15541 acggtgcttg agcatcatcc gcattacgcg atgaccgcgc tggcgctggg cgatcagcat
    15601 ttgtgggtca ataagctgga cgaaccgctg caagctgcgc tacgtatccg cattcaggct
    15661 tccgatgttt ctctggtttt acaaccgccg cagcaaacca gcattcgtaa cgtattgcgg
    15721 gcaaaagttg ttaatagtta tgacgacaac ggccaggtgg aagtggaact ggaagtcggc
    15781 ggtaaaacgc tgtgggcgcg tatcagcccg tgggccaggg atgaactggc gatcaaacct
    15841 ggcctgtggc tgtacgcgca aattaaaagt gtgtcgataa ccgcctgatt aaatcaggtg
    15901 gctataaatg aactgggcaa tgctgtcggt ggtgttatca ccaatcacaa tgttggcgcg
    15961 cgcttttacc gcgtcatcgg cgttgcccat cgccacgcct gtaccagcgg cttccagcat
    16021 actgatatca ttaaagctat cgccgaatgc cacgacgttt tccatcgacc aaccttgcgc
    16081 ctcaacccat ttcgtcaaac gtttaccttt gctgttgccg ccgcgtgcaa tatcaacctg
    16141 atcgtgccag gaccattcac actccagtcc cagttcatgt tcgacatgct taccaaaatg
    16201 ctgcaattgc ggcaggtcat cgtgcgtcag ggcgaacttc catacggcgt taacttgttg
    16261 cgccgtttca gccagagaag cgacttgtgt gaaagtcgga cgctgttccg gcggcagggt
    16321 ttgcgcccag ttagatgtgc gaatgacatg cccggtcggg tgctcataga ccattgcatc
    16381 atcgacatac atcagaccgt gaatgtggtg ttcattcagc atctcaatga gttgcagggc
    16441 tttaataacg ggcattgggt ccgcttccag cacggttttt gcatgataat catacaaata
    16501 ggtgccatta cagcaaatag caggtgtatc cagcgccagc gcctgataaa aaggatgaat
    16561 agcgacgtga tggcgacctg tgacgatgat taattgatag cctgcttcgc gagcgcgggc
    16621 cagggcttct atcgatgaag gaagcagggt ctttttcggg gtcaataagg tgccgtctaa
    16681 gtcgagagca atcacgcgtg tggtcatggc gtattccaga ttaaggttaa gaattttcgt
    16741 ctgcgcgaat ggtacaccga taccactatc ggacaaaatt ctgcgtttta attcagcatt
    16801 caccgccaaa agcgactaat tttagctgtt acagtcagtt gctaaatgca aaggagcatt
    16861 catgaagcaa acagtttata tcgccagccc tgagagccag caaattcacg tctggaatct
    16921 gaatcatgaa ggcgcactga cgctgacaca ggttgtcgat gtgccggggc aggtgcagcc
    16981 gatggtggtc agcccggaca aacgttatct ctatgttggt gttcgccctg agtttcgcgt
    17041 cctggcgtat cgtatcgccc cggacgatgg cgcactgacc tttgccgcag agtctgcgct
    17101 gccgggtagt ccgacgcata tttccaccga tcaccagggg cagtttgtct ttgtaggttc
    17161 ttacaatgcg ggtaacgtga gcgtaacgcg tctggaagat ggcctgccag tgggcgtcgt
    17221 cgatgtggtc gaggggctgg acggttgcca ttccgccaat atctcaccgg acaaccgtac
    17281 gctgtgggtt ccggcattaa agcaggatcg catttgcctg tttacggtca gcgatgatgg
    17341 tcatctcgtg gcgcaggacc ctgcggaagt gaccaccgtt gaaggggccg gcccgcgtca
    17401 tatggtattc catccaaacg aacaatatgc gtattgcgtc aatgagttaa acagctcagt
    17461 ggatgtctgg gaactgaaag atccgcacgg taatatcgaa tgtgtccaga cgctggatat
    17521 gatgccggaa aacttctccg acacccgttg ggcggctgat attcatatca ccccggatgg
    17581 tcgccattta tacgcctgcg accgtaccgc cagcctgatt accgttttca gcgtttcgga
    17641 agatggcagc gtgttgagta aagaaggctt ccagccaacg gaaacccagc cgcgcggctt
    17701 caatgttgat cacagcggca agtatctgat tgccgccggg caaaaatctc accacatctc
    17761 ggtatacgaa attgttggcg agcaggggct actgcatgaa aaaggccgct atgcggtcgg
    17821 gcagggacca atgtgggtgg tggttaacgc acactaaccg ctgatttacc cggcgcagtc
    17881 tctcctgcgc cggtgtatta acctatctcc tgtaacgcgt gtctctggcg ttcgacgata
    17941 ttggtccaca aattgtcttt atcgtcagtc cataaattaa tcagcaaggc aaaaaagcgt
    18001 tctgctgctg gagaaagtac ggcatcttta cggcgaatta ttcccaatgt tcgacgtata
    18061 acgggttcca ccaatgggat accaataatc gaagaatagg gcgcatgagg cattgccagg
    18121 ccaggaagcg ccgaaatccc cagtcccgcc tccaccagtc ctaatgacgt cgaaagatga
    18181 cgcacttcgt aaaaccagtc cagcttccag ggcttgtcgg ccagctgttg ttctatcaac
    18241 agtcggttgc cgctggagga gcgtacgcca atcattttgt aacccactaa ctcctgccat
    18301 tctacaagct gctttttggc caatggatgg tcacgccgac aggccagcac gaacggctcg
    18361 ttgaccagtg gggtaaaatc aatggatgaa tttgtgacgt tgttcatgtt tatgccaaag
    18421 tctgattcgt tacacagcac cgattccatg caattattcg tgccttgttc cagaatccgc
    18481 actttaatat tgggatacag ctcattaaat ttaccgattg ccagcggtaa aaaataaaat
    18541 actgcggtcg gaatacacgc taacgtcacc ataccacgat gataagcatt catatcacga
    18601 atattaaaaa gcgtttcatc gaatttcttt attaattccc gcgcctccgg gagcaacctt
    18661 tttcctgctt ttgttaacgt aaccttgcga gttgtacgct caaatagttg aatatgtaaa
    18721 tcttcctcca tcttttttat tcttcgcgtt aatgcaggtt gcgtaatatt gagtaattta
    18781 gcggcattgt taaacgaact ggactctgcc agtatgacaa atgccttcat acttgataat
    18841 tcatgcttca ttattactcc ggaaaatgga agcgacgatt ttgggtggct ggccgttaaa
    18901 aattttaact gcatttagcc aacttaaatt aatgaaaaaa tgttattaat cgttgagcta
    18961 aagtcattag agatgctttg cccttaatgt aaccatatcg caataagtta tgtttttaaa
    19021 ttgagggcat tattatgaaa aaaataccct gcgtgatgat gcgaggtgga acctcgaggg
    19081 gcgcgttcct gttagcggaa catttacccg aagatcaaac gcagcgcgat aaaatattga
    19141 tggcaattat gggttccggt aacgatctgg aaattgacgg tattggcggc ggtaatccac
    19201 tgaccagtaa agtcgccatt attagccgtt ccagcgatcc gcgtgctgat gtcgattatc
    19261 tgtttgcgca ggtaatcgtt catgagcaac gtgtcgatac cacgcctaac tgcggcaata
    19321 tgctgtctgg tgttggggca ttcgccattg aaaatggttt gattgcagcg acttcgccag
    19381 ttactcgcgt acgtatccgc aacgtcaata cgggtacgtt catcgaagct gatgtgcaaa
    19441 cgccaaatgg tgttgtcgag tacgagggta gcgccagaat tgacggcgta ccgggtactg
    19501 ccgcaccggt tgcgctcact ttcctgaatg ccgctggaac caaaaccgga aaagttttcc
    19561 cgactgataa tcagattgat tattttgacg atgtcccggt gacctgtatc gatatggcga
    19621 tgccagtcgt cattattccg gctgaatatc tgggaaaaac aggttatgaa ttaccggcgg
    19681 aactggatgc cgacaaagca ttattagccc gcattgaatc tatccgtcta caagcgggta
    19741 aagcaatggg cttaggtgat gtcagtaata tggttatccc taaacctgtg cttatttctc
    19801 cagcgcagaa aggcggggca attaatgtgc gttattttat gccgcattct tgccatcgcg
    19861 cgctggcgat aaccggtgct attgctattt ccagtagttg tgcattggaa ggcaccgtca
    19921 cccgacaaat cgtcccttct gtaggatacg gcaatatcaa tattgaacac cccagtggtg
    19981 cgctcgacgt tcatttaagt aatgaaggtc aggatgccac gacgttacgc gcatctgtta
    20041 ttcggacgac cagaaaaata ttttccggtg aagtttatct tccctgaaaa aattcgttgt
    20101 caggataagg acaatcaata aaggacttct gtatgagtca tacagaaaga acaggatttt
    20161 aaatgaataa gaaatcgtta tggaagctaa ttctgatatt agcgatccca tgtattattg
    20221 gttttatgcc agctccggca ggattaagcg aactggcgtg ggtgcttttt ggtatttacc
    20281 tggcggccat tgtggggctg gttatcaagc ctttcccgga acctgtcgta ctgttaattg
    20341 ccgttgctgc ctcaatggtg gtggtcggta acttatccga cggtgcgttt aaaaccaccg
    20401 ccgtattaag cggttactct tcaggtacca cctggctggt gttctcggcg tttaccttaa
    20461 gcgccgcatt tgtgaccacc ggtttaggta aacgtattgc ctatctgctg attggtaaaa
    20521 tcggtaacac cacgctgggt ctgggttacg ttacggtatt cctcgatctg gtactggctc
    20581 cggcaacacc gtctaacacc gcgcgtgcgg gcggcattgt gttaccgatc atcaacagcg
    20641 tggcggtggc tttggggtcc gaaccggaaa aaagtccgcg tcgtgtcgga cattacctga
    20701 tgatgtccat ttacatggtc accaaaacca ccagctatat gttctttacc gcaatggcgg
    20761 ggaacattct ggcgctgaaa atgatcaacg acattctgca cctgcaaatt agctggggtg
    20821 gatgggcgct ggcagccgga ttgccgggca tcattatgct gctggtcacc ccgctggtga
    20881 tttacaccat gtatccacca gaaattaaga aggtggataa caaaaccatc gctaaagcgg
    20941 gccttgccga actaggaccg atgaaaatcc gcgaaaaaat gctgctcggt gtctttgtgc
    21001 tggcgctgct gggctggatt ttcagtaagt ctctgggggt tgatgaatcc accgtggcaa
    21061 tcgttgttat ggcaaccatg ctgctgctgg gtatcgttac ctgggaagac gtggttaaaa
    21121 ataaaggcgg ctggaatacc ttaatctggt acggcggtat tatcggctta agctccttat
    21181 tatcgaaagt taaattcttc gaatggttag ctgaagtctt taaaaataac ctggcatttg
    21241 atggtcacgg taacgttgct ttcttcgtta ttattttcct cagcattatc gtgcgttatt
    21301 tcttcgcttc cggtagtgcc tatatcgttg ctatgttacc ggtatttgcc atgctggcga
    21361 acgtctccgg cgcaccgtta atgttaaccg cgctggcact gttgttctcc aactcctatg
    21421 gcggcatggt tactcactat ggcggcgcgg caggtccggt catctttggc gtgggttata
    21481 acgatattaa atcctggtgg ttggtcggtg cggtactgac gatattaacc ttcctggtgc
    21541 atatcaccct cggcgtgtgg tggtggaata tgctgatcgg ctggaacatg ctgtaaatat
    21601 tctcgtcata cttcaagttg catgtgctgc gtctgcgttc gctcacccca gtcacttact
    21661 tatgtaagct cctggggatt cactcgcttg tcgccttcct gcaactcgaa ttatttagag
    21721 tatatccatt tattatcttt ctgcgcactt cacggtgcgc agatatctgg agcatttgat
    21781 gatcaagtta tctgaaaaag gcgtgtttct cgccagtaat aacgaaataa ttgccgaaga
    21841 acatttcacc ggcgaaatta aaaaagaaga agccaaaaaa ggcactattg cctggtctat
    21901 tctctcttcg cataatacgt ccggaaatat ggataaactt aaaattaagt ttgattcatt
    21961 agcctctcac gatattacct ttgttggtat tgtacagacc gctaaagcgt ccggtatgga
    22021 acgtttcccg ctgccgtatg tgctgaccaa ctgccataac tcactctgcg ccgtcggcgg
    22081 cactattaac ggtgatgacc atgtttttgg tttatcggcg gcccagcgtt atggcggtat
    22141 ttttgtgcct ccgcatattg cggtcatcca tcaatatatg cgtgagatga tggcaggcgg
    22201 cggcaaaatg atcctcgggt cagacagcca cacccgttac ggtgcattag ggacaatggc
    22261 agtcggtgag ggcggcggtg agttggtaaa acagctgctt aatgacacct gggatatcga
    22321 ctatccgggc gtggttgcgg tgcatctgac cggaaaacct gcgccgtatg tggggccaca
    22381 ggatgtggcg ctggctatca ttggcgcggt gttcaaaaac ggttacgtca aaaacaaagt
    22441 catggagttc gttggaccgg gcgttagcgc gctctctacc gatttccgta acagcgttga
    22501 cgtgatgacc actgaaacga cctgtttaag ttctgtctgg caaaccgatg aagaagtcca
    22561 taactggctg gcgctgcacg gtcgcggcca ggattactgc cagcttaacc ctcaaccgat
    22621 ggcgtactac gatggctgca tcagcgttga tttaagcgcc atcaaaccaa tgattgcgct
    22681 gccgttccac ccgagcaacg tgtatgaaat cgacacactg aaccagaacc tgaccgacat
    22741 tctgcgtgag attgaaattg agtccgaacg cgtggcgcac ggtaaagcca aactctcgct
    22801 gctggataaa gtggaaaatg gtcgcctgaa agtgcagcag gggattatcg cgggctgttc
    22861 tggcggtaac tacgaaaacg tcatcgcggc ggcgaatgca ctgcgcggtc aatcctgtgg
    22921 caatgacacc ttctcgctgg cagtttaccc gtcatcacag ccggtgttta tggatctcgc
    22981 caaaaaaggt gtggtagcag atttgattgg cgcaggcgca atcatcagaa ccgcgttctg
    23041 cggcccatgc tttggcgcgg gcgatacgcc aatcaacaac ggtttgagta ttcgccacac
    23101 cacgcgtaac ttcccgaacc gcgaaggctc taagccagct aatgggcaga tgtcagcggt
    23161 ggcgttgatg gacgctcgtt ctatcgctgc gactgcggca aacggtggct atttaacctc
    23221 tgccagcgaa cttgattgct gggacaacgt gccggagtac gccttcgatg taacgccgta
    23281 taaaaaccgt gtttatcagg gctttgtgaa aggggcaact cagcaaccgc tgatttacgg
    23341 gccgaacatt aaagactggc cggaattggg tgcgctgact gacaatatcg tcctgaaagt
    23401 gtgctcgaag atcctcgacg aagtgaccac caccgacgaa ctgattcctt ccggtgaaac
    23461 ctcttcttat cgttcaaatc cgattggtct ggcggagttt accctgtctc gccgcgatcc
    23521 cggttatgtt agcagaagta aagcgactgc tgagctggaa aatcagcgtc tggcggggaa
    23581 tgtcagcgag ctgacagagg tgtttgcgcg cattaagcag attgctggtc aggagcatat
    23641 tgatccgctg caaactgaaa ttggcagcat ggtctatgcg gtgaaaccag gcgatggttc
    23701 tgcgcgtgaa caggcggcga gctgccagcg tgtgattggc ggtctggcga atattgccga
    23761 ggagtacgcg actaaacgct atcgttctaa cgtcatcaac tgggggatgt taccgctgca
    23821 aatggcggaa gtaccaacct ttgaagtggg ggattacatt tacatccctg gcattaaagc
    23881 ggcgctggat aatccgggta cgacgtttaa aggttatgtg atccatgaag atgcgccggt
    23941 aacggaaatt acgctctata tggaaagtct gactgctgaa gagcgcgaga ttatcaaggc
    24001 gggtagtttg attaacttca ataaaaaccg tcagatgtaa aaagcgccat gtgaatgtag
    24061 gtcgcattcg gcacttattg tcggatgcga tgcttgcgca tcttatccga cctacgaatc
    24121 gcatcgaatc tgtaggccag ataaggcatt ttcgcagcat ccggcactta ttgtcggatg
    24181 cgatgcttgc gcatcttatc cgacctacaa atcgcatcga accgtaggcc ggataaagcg
    24241 tttacgccgc atccggcaaa tagttaattg ctcttacttc ttcgcctctg caaccacttt
    24301 actacccacg ccgcggttat tgtattccca catgcggttg tagttagtgt cattcagatt
    24361 gcgctgtatt tcgtcgttat catctacgct gccggtatta cccgcaaacg gacgattaga
    24421 gatcaccgca tcggcccacg gtttagccgt gttaaaacct tcgttgatgg cgctatcacg
    24481 gatcaccacc tgaccgttgg tattggcatc aacatccagc gagcggccca gttgcgccac
    24541 accatcaccg aaagcattga aacggctgtt tacggcgagg aaaccgtagt aaatgttgga
    24601 cagcgtagcc ggtgcaaaca catacgcttc ttgctgagta cgtgagttca ccacgcggaa
    24661 ttcggtgtta tcgaacacca ctgcgccgcg accagaaacg atatccacat ccccttcaat
    24721 gtagctgttg gtcaccagcg tacgcggctg acgattcgtt tccagacggt tctgcacacc
    24781 gctgttggtg acaaagaagg tgttctgacg accgagaatg ttaacgttgt taatctgtac
    24841 ctggtcacca tcagtacgca gtgccaccgc cggatggtta cctgcatcta cgctatcgcc
    24901 cagcgtgttt tcgatggtca gattttgcag ttgcaggcca ttgttttgtg accagaagac
    24961 cgcagagcag agaacaccga tactgtcgct gcgtttgctc tggcagctat cgtacatata
    25021 ccacgctggt ttacctggca tatatttgcc gcgcgggttg acgtcgtgac gccagtcggc
    25081 agggctcatg ccaccatcaa gggaaagccc aatcttcaca tcaatcggtt tttcacctgt
    25141 accgtacaga gtaattccac ccggagcggc agggacatat accgttccct gatactcacc
    25201 aggcatcacg gcaatatact ggcgcttgtt ggtacgcttg ataattgccg catctaccgc
    25261 cgcctgaatc gtggtatgcg ttacaccttg agtgcccgcc gggccgacaa caaagtcagg
    25321 ttgcgcaggc agggtaatcg gggaaggatt ccacgctgca gcacctggtg tcagggatgc
    25381 aaaatagtgt tgagcatcga aattctgcgc ttcttttgcc gacagaatcg ggcgagaaga
    25441 ggtaccaggc gcggtttgat cagaaggacg ttgatcgggc ggggttgagc tacaggcggt
    25501 cagcgtcacg ccaaaagcca atgccagcgc cagacgggaa actgaaaatg tgttcacagg
    25561 ttgctccggg ctatgaaata gaaaaatgaa tccgttgaag cctgcttttt tatactaact
    25621 tgagcgaaac gggaaggtaa aaagacaaaa agttgttttt aataccttta agtgatacca
    25681 gatggcattg cgccatctgg cagagtgatt aactaaacat cgcagtaatc gaggcgcttg
    25741 ccagagagtg gaaatgaacg ttaaacccga ccatcgcgcc gctggcacct tcatcgacat
    25801 caatacgttc tatatccagc gcgtgaacgg taaaaatgta gcgatgagtt tcgcctttcg
    25861 gcggtgctgc gccatcgtac ccggttttac caaagtcggt acgcgtctgc aaaacgccgt
    25921 ctggcattgc taccagacca gagccaaacc cttgcggtaa tacgcgggta tcagcgggta
    25981 agttaacaac tacccagtgc caccagccgg agccggttgg cgcatccggg tcgtagcagg
    26041 tgacaacaaa acttttcgtt cccgcaggaa catcatccca cgccagatgc ggtgaaatat
    26101 tatcgccatc gtaacccatg ccgttaaaga catgacgatg cggcaattta tcgccatcgc
    26161 gcagatcgtt actgatgagt ttcatgaacc ctcctttctt gtttgcagaa agtgtagcca
    26221 gaaaccctca cgcggacttc tcgttattgg caaaaaaatg tttcatcctg taccgcgcgg
    26281 ttaaccgctg cggtcagacg ctgcaactgt tgcgggagaa taatataggg cggcatcagg
    26341 taaatcagtt tgccaaaagg ccggatccag acaccctgtt cgacaaagaa tttttgcagc
    26401 gccgccatat tcaccggatg agtggtttcg accacgccaa tggcccccag tacgcgcaca
    26461 tcggcaacca tttcggcatc acgggcgggg gcaagttgct cgcgcagctg tacttcaata
    26521 tccgccacct gttgctgcca gtcgccagat tcgagaatcg ccaggctggc gtttgctgcc
    26581 gcgcaggcca gcggattgcc cataaaagtt ggcccatgca taaagcaacc ggcttcaccg
    26641 ttactgatgg tttctgcaac ctcgcgcgtg gtgagtgtgg cggaaagggt cattgtgccg
    26701 ccggttaagg ctttaccgag gcacaaaatg tccggcgcga tttctgcatg ttcacaggca
    26761 aacagtttcc cggtacgacc aaatccagtg gcgatctcgt cggcaatcag caagatacct
    26821 tcgcgatcgc atattttgcg gattcgtttt aaccattccg gatggtacat gcgcatcccg
    26881 cctgcgccct ggacaatcgg ttcaatgatc accgccgcga tttcatgacg atgcgccgcc
    26941 atcaggcggg caaagcccac catatcgcgc tcatcccatt cgccatccat gcggctttgc
    27001 ggggcgggag caaacaggtt ttctggcagg tagcctttcc acagactgtg cattgagtta
    27061 tccggatcgc acaccgacat cgcgccaaag gtatcgccat gataaccatt gcggaaggtc
    27121 agaaaacgct ggcgcgcttc gcctttggct tgccagtact gcaacgccat tttcatcgcc
    27181 acttccaccg ctacggaacc ggagtccgcg agaaaaacgc actccagcgg ttgcggcgtc
    27241 atcgccacca gtttgcggca cagctcaatg gctggcgcat gggtgatacc gccaaacatc
    27301 acatgcgaca tggcatcaat ttgcgacttc atcgccgcat taagctgcgg gtgattgtag
    27361 ccgtggatcg ccgcccacca ggacgacata ccgtcaacca ggcgtctgcc gtcagacaaa
    27421 atcagctcgc aaccttcggc gctcaccacc ggataaaccg gcagagggga ggtcatggat
    27481 gtgtatgggt gccagatatg gcgttggtca aaggcaagat cgtccgttgt cataatcgac
    27541 ttgtaaacca aattgaaaag atttaggttt acaagtctac accgaattaa caacaaaaaa
    27601 cacgttttgg agaagcccca tggctcaccg cccacgctgg acattgtcgc aagtcacaga
    27661 attatttgaa aaaccgttgc tggatctgct gtttgaagcg cagcaggtgc atcgccagca
    27721 tttcgatcct cgtcaggtgc aggtcagcac gttgctgtcg attaagaccg gagcttgtcc
    27781 ggaagattgc aaatactgcc cgcaaagctc gcgctacaaa accgggctgg aagccgagcg
    27841 gttgatggaa gttgaacagg tgctggagtc ggcgcgcaaa gcgaaagcgg caggatcgac
    27901 gcgcttctgt atgggcgcgg cgtggaagaa tccccacgaa cgcgatatgc cgtacctgga
    27961 acaaatggtg cagggggtaa aagcgatggg gctggaggcg tgtatgacgc tgggcacgtt
    28021 gagtgaatct caggcgcagc gcctcgcgaa cgccgggctg gattactaca accacaacct
    28081 ggacacctcg ccggagtttt acggcaatat catcaccaca cgcacttatc aggaacgcct
    28141 cgatacgctg gaaaaagtgc gcgatgccgg gatcaaagtc tgttctggcg gcattgtggg
    28201 cttaggcgaa acggtaaaag atcgcgccgg attattgctg caactggcaa acctgccgac
    28261 gccgccggaa agcgtgccaa tcaacatgct ggtgaaggtg aaaggcacgc cgcttgccga
    28321 taacgatgat gtcgatgcct ttgattttat tcgcaccatt gcggtcgcgc ggatcatgat
    28381 gccaacctct tacgtgcgcc tttctgccgg acgcgagcag atgaacgaac agactcaggc
    28441 gatgtgcttt atggcaggcg caaactcgat tttctacggt tgcaaactgc tgaccacgcc
    28501 gaatccggaa gaagataaag acctgcaact gttccgcaaa ctggggctaa atccgcagca
    28561 aactgccgtg ctggcagggg ataacgaaca acagcaacgt cttgaacagg cgctgatgac
    28621 cccggacacc gacgaatatt acaacgcggc agcattatga gctggcagga gaaaatcaac
    28681 gcggcgctcg atgcgcggcg tgctgccgat gccctgcgtc gccgttatcc ggtggcgcaa
    28741 ggagccggac gctggctggt ggcggatgat cgccagtatc tgaacttttc cagtaacgat
    28801 tatttaggtt taagccatca tccgcaaatt atccgtgcct ggcagcaggg ggcggagcaa
    28861 tttggcatcg gtagcggcgg ctccggtcac gtcagcggtt atagcgtggt gcatcaggca
    28921 ctggaagaag agctggccga gtggcttggc tattcgcggg cactgctgtt tatctctggt
    28981 ttcgccgcta atcaggcagt tattgccgcg atgatggcga aagaggaccg tattgctgcc
    29041 gaccggctta gccatgcctc attgctggaa gctgccagtt taagcccgtc gcagcttcgc
    29101 cgttttgctc ataacgatgt cactcatttg gcgcgattgc ttgcttcccc ctgtccgggg
    29161 cagcaaatgg tggtgacaga aggcgtgttc agcatggacg gcgatagtgc gccactggcg
    29221 gaaatccagc aggtaacgca acagcacaat ggctggttga tggtcgatga tgcccacggc
    29281 acgggcgtta tcggggagca ggggcgtggc agctgctggc tgcaaaaggt aaaaccagaa
    29341 ttgctggtag tgacttttgg caaaggattt ggcgtcagcg gggcagcggt gctttgctcc
    29401 agtacggtgg cggattatct gctgcaattc gcccgccacc ttatctacag caccagtatg
    29461 ccgcccgctc aggcgcaggc attacgtgcg tcgctggcgg tcattcgcag tgatgagggt
    29521 gatgcacggc gcgaaaaact ggcggcactc attacgcgtt ttcgtgccgg agtacaggat
    29581 ttgccgttta cgcttgctga ttcatgcagc gccatccagc cattgattgt cggtgataac
    29641 agccgtgcgt tacaactggc agaaaaactg cgccagcaag gctgctgggt cacggcgatt
    29701 cgcccgccaa ccgtacccgc tggtactgcg cgactgcgct taacgctaac cgctgcgcat
    29761 gaaatgcagg atatcgaccg tctgctggag gtgctgcatg gcaacggtta ataaacaagc
    29821 cattgcagcg gcatttggtc gggcagccgc acactatgag caacatgcag atctacagcg
    29881 ccagagtgct gacgccttac tggcaatgct tccacagcgt aaatacaccc acgtactgga
    29941 cgcgggttgt ggacctggct ggatgagccg ccactggcgg gaacgtcacg cgcaggtgac
    30001 ggccttagat ctctcgccgc caatgcttgt tcaggcacgc cagaaggatg ccgcagacca
    30061 ttatctggcg ggagatatcg aatccctgcc gttagcgact gcgacgttcg atcttgcatg
    30121 gagcaatctc gcagtgcagt ggtgcggtaa tttatccacg gcactccgcg agctgtatcg
    30181 ggtggtgcgc cccaaaggcg tggtcgcgtt taccacgctg gtgcagggat cgttacccga
    30241 actgcatcag gcgtggcagg cggtggacga gcgtccgcat gctaatcgct ttttaccgcc
    30301 agatgaaatc gaacagtcgc tgaacggcgt gcattatcaa catcatattc agcccatcac
    30361 gctgtggttt gatgatgcgc tcagtgccat gcgttcgctg aaaggcatcg gtgccacgca
    30421 tcttcatgaa gggcgcgacc cgcgaatatt aacgcgttcg cagttgcagc gattgcaact
    30481 ggcctggccg caacagcagg ggcgatatcc tctgacgtat catctttttt tgggagtgat
    30541 tgctcgtgag taaacgttat tttgtcaccg gaacggatac cgaagtgggg aaaactgtcg
    30601 ccagttgtgc acttttacaa gccgcaaagg cagcaggcta ccggacggca ggttataaac
    30661 cggtcgcctc tggcagcgaa aagaccccgg aaggtttaca caatagcgac gcgctggcgt
    30721 tacagcgcaa cagcagcctg cagctggatt acgcaacagt aaatccttac accttcgcag
    30781 aacccacttc gccgcacatc atcagcgcgc aagagggcag accgatagaa tcattggtaa
    30841 tgagcgccgg attacgcgcg cttgaacaac aggctgactg ggtgttagtg gaaggtgctg
    30901 gcggctggtt tacgccgctt tctgacactt tcacttttgc agattgggta acacaggaac
    30961 aactgccggt gatactggta gttggtgtga aactcggctg tattaatcac gcgatgttga
    31021 ctgcacaggt aatacaacac gccggactga ctctggcggg ttgggtggcg aacgatgtta
    31081 cgcctccggg aaaacgtcac gctgaatata tgaccacgct cacccgcatg attcccgcgc
    31141 cgctgctggg agagatcccc tggcttgcag aaaatccaga aaatgcggca accggaaagt
    31201 acataaacct tgccttgttg tagccattct gtatttggtt aaattgcgag cgagatcgcg
    31261 tcttcgattg actgcaattt aaccaattaa attctaaaat aatcacgaaa aaaattttac
    31321 ttccgcctca tgcggcgaat gtgggaattg cccaggcggc gggggatagg ggctggagac
    31381 agttatccac tattcctgtg gataaccatg tgtattagag ttagaaaaca cgaggcaagc
    31441 gagagaatac gcggcttgca cgcgaattgg cgttaaagac ggctcaaaga aatatctttt
    31501 attttttaac tggttagata aatgcaatgg cagtcactga acaggcatct cttgccataa
    31561 aactgtcatc actcatcttg acaaatgtta aaaaagccgt tgctttgggg ataacccggt
    31621 aaggccggag ttttatctcg ccacagagta aattttgctc atgattgaca gcggagttta
    31681 cgctgtatca gaaatattat ggtgatgaac tgttttttta tccagtataa tttgttggca
    31741 taattaagta cgacgagtaa aattacatac ctgcccgccc aactccttca ggtagcgact
    31801 catgagtaaa ccgttcaaac tgaattccgc ttttaaacct tctggcgatc agccagaggc
    31861 gattcgacgt ctcgaagagg ggctggaaga tggcctggcg caccagacgt tacttggcgt
    31921 gactggctca gggaaaacct tcaccattgc caatgtcatt gctgaccttc agcgcccaac
    31981 catggtactt gcgcccaaca aaacgctggc ggcccagctg tatggcgaaa tgaaagagtt
    32041 cttcccggaa aacgcggtgg aatatttcgt ttcctactac gactactatc agccggaagc
    32101 ctatgtaccg agttccgaca ctttcattga gaaagatgcc tcggttaacg aacatattga
    32161 gcagatgcgt ttgtccgcca ccaaagcgat gctggagcgg cgtgatgtgg ttgtggtggc
    32221 gtctgtttcc gcgatttatg gtctgggcga tcctgattta tatctcaaga tgatgctcca
    32281 tctcacggtc ggtatgatta tcgatcagcg cgcgattctg cgccgactgg cggagctgca
    32341 atacgctcgt aatgatcaag cattccagcg tggtactttc cgcgttcgtg gcgaggtgat
    32401 agatatcttc ccggcagaat cggatgacat tgcacttcgc gtggaactgt ttgacgagga
    32461 agtggaacga ttgtcgttat ttgacccgct gaccgggcag attgtttcca ctattccacg
    32521 ttttaccatc tacccgaaaa cgcactacgt cacaccgcgc gagcgcatcg tacaggcgat
    32581 ggaggagatc aaagaagagc tggccgccag acgcaaagtg ctgttggaaa acaacaaact
    32641 gctggaagag cagcggctga cccagcgtac ccagtttgat ctggagatga tgaacgagct
    32701 gggctactgt tcggggattg aaaactactc gcgcttcctc tccggtcgtg gaccgggtga
    32761 gccaccgccg acgctgtttg attacctgcc tgccgatggg ctgctggtcg tcgatgaatc
    32821 tcacgtcacc attccacaaa ttggcggcat gtatcgcggt gaccgggcgc gtaaagagac
    32881 actggtggag tacggcttcc gcctgccatc agcgctggat aaccgtccgc ttaagtttga
    32941 agagttcgaa gcattagcgc cgcaaaccat ctatgtttcg gcgacgccgg gtaattacga
    33001 gctggaaaaa tccggcggcg atgtggtgga tcaggtggtg cgtccaaccg gattgcttga
    33061 cccgattatc gaagtgcggc cggtggcgac acaggttgat gatcttcttt cggagattcg
    33121 tcagcgagcg gcaattaacg aacgcgtact ggtcaccaca ctgaccaagc ggatggcgga
    33181 agatcttacc gaatatctcg aagaacatgg cgagcgcgtg cgttatcttc actcagatat
    33241 cgacaccgtc gaacgtatgg agattatccg cgacttgcgt ctgggtgagt tcgacgtgct
    33301 ggtagggatc aacttactgc gcgaaggtct ggatatgccg gaagtgtcgc tggtggcgat
    33361 cctcgacgct gacaaagaag gcttcctgcg ttccgaacgt tcgttgatcc agaccattgg
    33421 tcgtgcggca cgtaacgtta acggtaaagc gattctctac ggcgataaga tcaccccatc
    33481 aatggcgaaa gcgattggcg aaaccgaacg tcgccgtgag aaacagcaga agtacaacga
    33541 ggaacacgga attacgccgc aaggcttgaa caagaaagtg gtcgatatcc tggcgctggg
    33601 gcagaacatt gccaaaacca aagcgaaggg cagaggaaaa tcgcgcccga ttgttgagcc
    33661 ggataatgtg ccgatggata tgtcgcctaa agcgttgcag cagaaaatcc atgagctgga
    33721 agggttgatg atgcaacacg cgcagaatct ggagttcgaa gaagcggcgc aaattcgtga
    33781 ccagttgcat cagctgcgtg agctgtttat cgcggcatcg taacaggata gcgaagaaga
    33841 ctgatgacaa acggaaaaca gcctgatgcg ctacgcttat caggcctaca ttttctccgc
    33901 aatatattga atttgcgcgg tttgtaggcc ggataaggcg ttcacgccgc atccggcata
    33961 aacaacgcgc actttgtctt caataggaag ccggaatttt ccttcggatt tccgttaacc
    34021 taaagcctgt aacgcctttt ccagcgcgtt atgtaacaac tggcggtcat gacgatacgg
    34081 aatatcgctg gcctccagta cctcctggat cacaatccgc tctttcaccg ccgagacatc
    34141 cacttttggc ccgacgatga ccgcatcaat gaccttttta ccaacatact gctccataat
    34201 tgccagcttg ctttccagct tcaaattagc cgcaggtaaa ctcaactcac gccccagatt
    34261 gccgatataa accatcggcg ctggcgtgcg gcgtaatgcc tgggcgattt ccttcagcag
    34321 cagaattggc atcaggctgg tataaaaact gccaggccca ataatgatga gatccgcttc
    34381 attgatagcg tgaaccgcct cacgcgttgc gggtacatta ggcgttaaca ataactcttg
    34441 aatcggcgta gttaactggt cgatattgac ctcgccgtaa acttcatgcc cctgatcgtc
    34501 aatcgccatc agatcaacag gatgctctga cattggaatc aaatgcgtat ccactttcag
    34561 cagattacga attaaattga tggcttccag aggccgcacg ctaaggtgat ccagcgcctt
    34621 taacatcaag tttccgagat tatgaccgga aagttcgcca ttgccaccaa aacggtattc
    34681 aaacatcgcg gaggcgacgc tcggttccgt tatcagctgg ttgaggcagt tgcgcatatc
    34741 gccccaggca atgccgcctt ctgaacggcg aatacgcccc gtcgagccac cattatcggt
    34801 ggtggtgacg atacccgtta aacgagaacc caaagacgaa agtgatgaga gaacgcgtcc
    34861 cagtccatgc cctccgccga gagcaacgac acgatcaaga tcagccagcg tacgattgcg
    34921 catatagttt cctggagtca gattatccgc gctacagtag cgcaaattgc ggggaaacag
    34981 caattaacct gccaatattg aggatacaaa ctattttctt ctacctctaa aggacgatgc
    35041 acgctatgcc tccctgatga tgtatatcaa agtaaaaccg ccattttccc ttattctgta
    35101 gcgaaatagc acgatcatga cgctatatac atgattacat agcgaaagtg tggatggtaa
    35161 aaatctcatt tacacgctag tatcggcata accactaaac actctagcct ctgcacctgg
    35221 gtcaactgat acggtgcttt ggccgtgaca atgctcgtaa agattgccac cagggcgaag
    35281 gaagaaatga cttcgcctcc cgtatctgga aaggtgtaca tggcttcaca actgactgat
    35341 gcatttgcgc gtaagtttta ctacttgcgc ctgtcgatta ccgatgtgtg taactttcgt
    35401 tgcacctact gcctgccgga tggctacaaa ccgagcggcg tcaccaataa aggctttctt
    35461 accgtcgatg aaattcgccg ggttacgcgc gccttcgcca gtctgggcac cgaaaaagtg
    35521 cgcctgacag gaggagagcc gtctttacgc cgcgacttta ccgatatcat cgccgctgtg
    35581 cgggaaaacg acgctatccg ccagattgcg gtcacaacca atggttaccg tctggaacgc
    35641 gatgtggcga gctggcgcga tgcgggactt actggcatta acgtcagtgt cgacagtctg
    35701 gacgcccgcc agtttcacgc tattaccggg caggataaat tcaaccaggt catggcaggg
    35761 attgatgctg catttgaggc cggttttgag aaggtcaaag tcaataccgt gctgatgcgt
    35821 gatgttaatc atcaccagct cgacaccttt ctgaactgga tccagcatcg ccctatccag
    35881 ctgcgtttca tcgaactgat ggaaacgggc gagggcagcg agctcttccg taagcatcac
    35941 atctctggtc aggttctgcg tgacgaacta ctgcgtcgcg gctggatcca ccaattacgt
    36001 caacgcagcg acggtcccgc gcaagtcttt tgccatccag attacgccgg agagattggc
    36061 cttatcatgc cgtatgaaaa agacttctgc gccacttgca accgcctgcg cgtttcctcc
    36121 attggtaaac tccatctctg cctgtttggt gaaggcggcg ttaacctgcg cgatctgctg
    36181 gaagacgata cccagcaaca ggcgctggaa gcgcgtattt cagcggcgct gcgggagaag
    36241 aaacagaccc atttcctgca tcaaaacaac accggtatta cgcaaaactt atcgtacatt
    36301 ggcggctaaa acgtcaaaag gagagatcag atgagtcagg taagcactga atttatcccg
    36361 acccgtattg ctattcttac ggtttctaat cgtcgcggtg aagaagacga tacctccggt
    36421 cactatctgc gcgattcggc gcaagaagcg ggccatcacg ttgtcgataa agccattgtg
    36481 aaagaaaacc gctacgctat tcgcgctcag gtatctgcgt ggatcgccag cgacgatgta
    36541 caagtggtat tgattacggg tggtactggc ctgacggaag gtgatcaggc tcccgaagca
    36601 ttgctgccgt tgttcgaccg tgaagttgaa ggttttggtg aagtgttccg gatgttgtcg
    36661 tttgaagaga ttggcacttc cacgttgcaa tctcgtgcgg tagcgggcgt cgccaacaaa
    36721 acgctgattt tcgccatgcc gggttcgacc aaagcgtgcc gtaccgcatg ggaaaatatc
    36781 atcgcgccgc agctggatgc ccgtacgcgt ccgtgtaatt tccatccaca tttgaagaaa
    36841 taagtatgtc gcaactgacc catatcaacg ccgctggcga agcgcacatg gtggatgtct
    36901 ccgccaaagc ggaaaccgtg cgtgaagcgc gggcggaagc ctttgtcacc atgcgcagcg
    36961 agacgctggc gatgattatt gatggtcgcc accacaaagg cgacgtattt gccactgcgc
    37021 gtattgccgg tattcaggcg gcaaaacgca cctgggatct gatcccgctc tgtcatccgc
    37081 tgatgctcag caaagttgaa gtcaatttac aggccgagcc ggagcacaat cgggtgcgta
    37141 tagaaacctt atgccgcctg accgggaaaa ccggtgtcga aatggaagca ttaaccgcgg
    37201 cctccgtggc ggcgctgacc atttatgaca tgtgcaaagc ggtgcaaaaa gatatggtga
    37261 ttggtccggt acgtttgctg gcgaagagcg gcggcaagtc gggtgacttt aaggtggaag
    37321 cggatgatta aagttctttt tttcgcccag gtgcgcgagt tggtgggaac agatgcaacc
    37381 gaagtggctg cggatttccc aactgttgaa gcgttacgcc agcacatggc tgcgcagagc
    37441 gatcgctggg cgctggcgct ggaagatggc aaattactgg ctgccgtcaa ccagacgctg
    37501 gtgagttttg accatccgct gactgacggc gacgaagtag ctttcttccc gccggtaacc
    37561 ggaggttaag atggcagaaa ccaaaattgt tgttggtccg cagccgttca gcgtaggaga
    37621 agagtacccg tggctggcgg agcgtgacga agacggtgcg gtagtcacct ttactggtaa
    37681 ggtgcgcaac cataacctgg gcgacagcgt caacgcatta accctcgaac actatccggg
    37741 gatgactgaa aaagcactgg cagaaattgt tgatgaagcg cgtaaccgct ggccgctggg
    37801 gcgcgtcact gtgattcacc gcatcgggga attatggccg ggcgatgaaa tcgtttttgt
    37861 cggtgtcacc agtgcgcatc gcagcagtgc gtttgaagcc gggcagttta ttatggatta
    37921 tctcaaaacc cgcgcaccgt tctggaagcg cgaagccacg ccggaaggcg accgctgggt
    37981 tgaagctcgg gagagcgatc agcaggcggc aaaacgctgg tagttttttg ttagccggat
    38041 aaggcaccgc tgcgtccggc aatttcaccg ctcagtacat acgtttacgc tgcgtcgatg
    38101 cacagcctca tcattttgca gtatccttaa gatattcctt atatcttcag gagatcgtca
    38161 tggacagatt cccacgttct gattcaatcg tacaaccccg ggctggcttg caaacttata
    38221 tggctcaagt ctatggctgg atgaccgttg gcttgttgct gaccgcattt gttgcctggt
    38281 atgcggctaa ttccgcggcc gtgatggagc tgttgttcac taaccgtgtc tttttaatcg
    38341 gtctgatcat cgcgcaatta gcattggtta ttgtgttatc agcgatgatt caaaagctga
    38401 gcgcaggtgt aacgacgatg ctctttatgc tttattcggc gctgacgggt cttacgcttt
    38461 ccagtatatt cattgtctat accgctgctt ctatcgccag tactttcgtc gttactgccg
    38521 ggatgttcgg cgcaatgagc ctgtacggtt acaccacgaa gcgcgattta agtggctttg
    38581 gcaatatgct gtttatggcg ttaatcggca ttgtgctggc atcgctggtc aacttctggt
    38641 tgaaaagcga agcattgatg tgggcagtta cctacatcgg cgtgattgtc tttgtcggat
    38701 tgacggcgta tgacacgcag aaactgaaaa atatgggtga gcagattgat acccgcgaca
    38761 cgtcgaacct gcgcaaatat tccattcttg gcgcgttaac cttgtatctg gacttcatca
    38821 acctgttcct gatgttgttg cggatcttcg gcaaccgccg ttaattcttt ttcaccatca
    38881 ctatcccggc catgtgtcgg gatttttttc ttactaaaaa cgacacttaa caagtaccag
    38941 gtataaaata tgccttatgg acgagcggaa gcgttttctg tatccataaa tgcaaaagta
    39001 ttttgtatgc gtggttttaa atttattgat ggtgaatatt aatatttttt ctaaggataa
    39061 ctaaaagaat ggaatcatac tcgcaaaaca gcaataaatt agattttcag cacgaggcca
    39121 ggatattaaa cggtatatgg ctcattaccg ctttaggttt ggtggcaacc gcaggactag
    39181 cctggggagc taagtatctc gaaattacgg caaccaaata tgattcacca ccaatgtatg
    39241 tcgccatagg gttattatta ctttgtatgt atggcttaag taaggatatc aacaagataa
    39301 atgccgccat cgcgggcgta atatatctgt ttttactctc tttggtggcg attgtcgttg
    39361 caagtttagt tcctgtatat gccattatca tcgtgttcag cactgcgggc gcgatgtttt
    39421 taatcagtat gctggccggt ttattattta atgttgatcc tggttctcac cgttttatca
    39481 ttatgatgac gttgacaggg ttggccctgg taatcatcgt gaatgcggca ttaatgagtg
    39541 aacggcccat ttgggtaata agttgcttaa tgattgtgtt atggtcaggc attatctcgc
    39601 atggacgaaa taagctcctt gaattggcgg ggaaatgcca tagtgaagag ttgtggagtc
    39661 cggttcgttg cgcttttaca ggtgcattaa cactctatta ctattttatc ggcttctttg
    39721 ggatacttgc cgcgatagct ataacgcttg tctggcaaag gcatacgcgt ttttttcatt
    39781 agccgtaaat gcacatacta aagaacttaa ctaaacttca catcgccgct tcatttttcg
    39841 cccgtagctt cttcgcctgg ctttccagca acaggtaaca gatcagcgcc agcagcagtg
    39901 ggataaagta atacagcaca cggtaagcga gtagggcggc gataattgta cctttggagg
    39961 tatgctcccc agccagtagt gcgataaaca ccgcttccag cacaccgatc cccgccggaa
    40021 tatgcacgat gacgccagca atactactaa ccagtaacac gcccagtaca aagaaatagt
    40081 tcacgctttg accaagtaac agccagataa tcgcccccat taccatccag ttaacgctgg
    40141 aaatcagcat ctgagcgagg gcgaatttcc atgaaggcag caccagcttt tgccctttga
    40201 tggtcatatg gcggtgcttc gcgaaagcgc aaaaccacaa ataaaccgcg ataatcatca
    40261 gtaagccaat gccgagaata cgcagcgtag tttgatcgac ataccagtga tccggcaact
    40321 ccaccacgcc tgcggtaaag ataatccctg ccagtaaaat gtagcccagc cagttggtgg
    40381 taatactgag cgagaaaatc cgcgtaatag tgctaccggg caaccccaga cgagagtaca
    40441 aacgatagcg cataccaatg ccgccgaccc aggtactgag cgtcaggttg aaggcgtagc
    40501 agataaacga caccagcatc acctggcgct tcgccagttt gtgaccgcag taaaagcggg
    40561 cgagcaggtc atagcagccg taaatcagat agctgacgac caccagcccg accgcactaa
    40621 gcagcgcaac gcgattgtag tcgcggatga ccttccagac ctcttcccag tccacttttt
    40681 tggcgtagac caccagcaac acaatcaccg cgataaaaaa cagccaggtg aggatcttct
    40741 ttgctaagcg ccagcgcggg tgtgatttac tcatcagggt tttacccccg tgttttcagt
    40801 ttctacccga tcctgcgttt ccattgtcgg ttgtgcgggc ggatcaacct gcgccagacg
    40861 tggcgtgtgt gccggaagcc agccaaccag cgccgggaag tggcgtaaaa agtggaacgc
    40921 cagcacgctt ttggtcaggt tccaccaggt gcgtttgggc agcatggttt catccacctg
    40981 ctgacaatct gcggcaataa tgccgttcag attatcgcgc agcgtctggt taaaatgacg
    41041 atcgtggatg atgacatttg cttcgagatt cagtgacaaa ctgagcggat cgagattact
    41101 ggaccctact gtcgcccagt gatcgtccat caatgccact ttgccgtgga gcgggcggcg
    41161 gcggtactca aaaacctgaa cgccgccttt aaccagatag ttatacagca agcgcgcacc
    41221 gactctgaca atcggcatat ccggttcgcc ctgaatgatc agtttgatcc gcaccccgcg
    41281 ccgtgccgct ttacgcaagg cgtgtaaaaa tcgatagccg gggaagaagt aggcgttggc
    41341 gataatcact tcccgccgcg cctgagtgag cattttcaaa taatggcgtt caatatcatc
    41401 gcgatgttct tcgttatcgc gccagaccag caatacctgc gcttctcccg gctggcggtt
    41461 ctcttccgct ttgtgatgac gtcgccacca gcgtcgtgcc gcgctctgtc caggcaggtt
    41521 ttccagctca aactggagaa tatcttcgac aatcggccct tcaaggcgta ccgcgtaatc
    41581 ctgtttagcc tctggaccgt agctggacat atgctcggcg gagtaattca gcccgccaat
    41641 aaaggctata cgcgcgtcga tcaccacaat tttgcgatgc atccggcgaa acacattggt
    41701 gcgcatacca aaaaggcgag ggcggggatc gtagtagcgg aacactacgc cagctgccgt
    41761 cagttcattg acaaactcat cgctgagatc cggcgaaccg tagccatcca gcaagacttc
    41821 cgctttaacc ccgcgttgcg ctgctgccag tagtgccgca tgcagttgtt tgccgacgtc
    41881 atcctcaaac cagataaacg tttcaagaat gatgcgttct tgtgcctcgc caatcgcctt
    41941 aaacaccgcg ggataatatt gctcgccgtt ttccagcaac tggatcttat tgccttcgcg
    42001 ccagctacat ttcataaatg aatctccgca cttaaagggg catgatcaga aaggtgtcgc
    42061 catgtccgca gcggcaacgc ggttggcgcg ctggcgctgg catttttgac gtagatcctg
    42121 tccagtcgta gtagaggaaa ttgcaccgga aacgtgcgcg ccgggcgtcc gtgggcgcgg
    42181 gtaaaaatct catccagtcc ggcctgcact tttaacggat gattagcttt ttgccgccag
    42241 tcattgaaat cacccgccac caataccggt tcgccgtccg gtagctcatt cacccattcg
    42301 gcgagcatcg caagctgcgc ctgacggtgc gcctcacgca ggcccagatg tacgcacatc
    42361 acatgaatcg cttttccggt catcggcggc acaatgcggc agtagagcac gccgcgcttt
    42421 tccgcaccat cgaccgaaac atcgcgattc tcataatgtt caatgggata acgcgacagt
    42481 acggcgttgc cgtgatgccc ttccgggtat acggcattgc gaccgtaggc aaaatcgctc
    42541 cacatagtgt cggcgagaaa ctcgtagtgc gaggtatcgg gccagttttc cacatgcagc
    42601 ggatgaactt cgtgcgcgcc catcacttcc tgcaggcaaa caatatcggc gctgacggta
    42661 cgcacggcgt cgcgaagttc cggcaaaatg aagcgtcggt taaacgcggt aaagcctttg
    42721 tgaatattga tggtgagcac cttgaacgaa aattgttgtg tttgatcggg cataattttc
    42781 ctgtctttgc ctcttatctc attgaaatag tgtagtcggc gtcacaaaaa ggtgcggtct
    42841 tacggaattt tccgtaaagt tcggtactct gagtaagtag agataaatta ttcaggagag
    42901 aagccatgaa gtggcaacaa cgtgttcgtg tcgcaacggg tctaagttgc tggcagatta
    42961 tgttgcattt actggtagtg gcgctgctgg tggtgggctg gatgagtaag actctggttc
    43021 acgtcggcgt gggattatgc gcactgtatt gtgtcacggt agtgatgatg ctggtgtttc
    43081 agcgccaccc cgagcaacgc tggcgtgagg tggcagacgt gctggaagag ctgaccacga
    43141 cctggtattt tggcgcagcg ctgattgtgc tgtggctgtt gtcccgcgtt ctggaaaaca
    43201 actttttgct ggcaattgca gggctggcaa tccttgccgg cccggcggta gtgtctttgc
    43261 tggcgaaaga taagaagtta catcacctta cgtctaaaca tcgcgtacgc cgctgaccct
    43321 gtcgtggccg ttatcaccag tagcggccac aaactattcc acacaatatc cagactcgca
    43381 tccttcaaat aaatctgctt ggtaatgtcc gtaaagtggc gaatagggtt aatccacgtc
    43441 aggttttgca gccataccgg catgttttcc accggagaaa cgtaaccgga aaggagaatg
    43501 gcgggcatca taaagacaaa cacgccgata aacgcctgct gttgtgttga acagagtgat
    43561 gaaatcaaca gaccgaatcc caccagcgat aaaccataaa tcaccatcgt aaagtagaac
    43621 agcgccagcg atccggcgaa ggggatttga tacgcccaga taccaatcgc cagcacaatg
    43681 gtggcctgga aggtggcgac aattaacgcc ggtacggctt tgccgatgaa gatctgccag
    43741 gtggtgagcg gcgaaaccag tagctgatcg agcgtacctt gttcacgttc gcgggcgacg
    43801 gaaagtgaag tgacgatcat tacgccgata gtggtgatca tggcgatcag tgacggcacc
    43861 acaaaccatt tgtagtcgag attcgggtta taccagttgc gtaccaccag ctcgctgttg
    43921 ttaggtttcg gttttccttc cagcagctcc tgctgataat ttttgacgat ctgttgcagg
    43981 tagttggcgg caatttgcgc actgttggag ttacgcccgt cgaggatcaa ctgcaaaggc
    44041 gcggtctgga aggtatccag tttgcgcgag aagtcagccg ggaaacgcac cagtagtaac
    44101 gccttttgtg tgtcgatggt tgggcggatc tcctgtgggc ttttcagcag cagcacatga
    44161 gtaaaggcgc tggcgcgggc aaaacgttgg gtcagctcca ccgaatgctc gccgttatct
    44221 tcatcgtaga tggcgatggt ggcgttagtc acttccagcg tggcggcgaa cgggaacagg
    44281 atcacctgaa ttagcacggg taaaatcaga atcgcgcggg tttgcggttc gcgcagcaac
    44341 gactgcaact ctttgcggat taacgtccat aagcgatgaa acatgctctt ctccctaatc
    44401 cagccgacgt ttggttttca gccacgtcag gccgataaac atcaccgccg aagcgatcaa
    44461 aaacagcacg tttaccacca gcaccactgg aatattcccg gcgaggaaca ggctttgcag
    44521 ggtgctgacg aaataacgag cgggaataat gtacgtcacc gcgcggatca ccgcgggcat
    44581 actgtcgatc tgaaaaataa agccggaaag cataatcgac ggcagaaaag cggcgttcag
    44641 ggcgacctga gcggcattga actggttgcg ggtaatcgtg gaaatcagca gccccatccc
    44701 cagggtactg agtaaaaaca ggctggagat aaaaaacaga atcagcagcg acccgcgata
    44761 cggcacgccg agaataaaca ctgacaccag catacacagc aacatcgcca gcatcccgag
    44821 aaagtaataa gggatcagct tacacagcag cagttccgtg cgggtaatct ccgtagagag
    44881 cagagcctcc atggtgccgc gttcccattc tcgcgccacc accagcgagg tgagaatcgc
    44941 gccgatgacc gtcatgataa tggtcaccgc accggggata atgaagtgct ggctaatcgc
    45001 cgccgggtta aaccagtagc gggtttgtac atcaataagc ggttcaaaag tctgcccgtt
    45061 gtcctccgct cgctgcattt gccagatctg ccagatccct tcgacatacc cctgtacaaa
    45121 gttagcggta ttcggctcac tgccgtcggt gatcacctga atcggtgcgg tggcgttggc
    45181 gcgctccatc tgttccgcaa aatccaccgg aataaccacc agaccgcgaa ttttccccgc
    45241 ctgcattttg gcgatcagtt cctgacggtt atcgctgatg gtggcgtcga tgtagggcga
    45301 accggtcatg gtgtgggtga aatccagcgc cgcttcgcta cgctgttcca gtaaaatccc
    45361 gacccgcagc ttgctggagt cgaggttaat gccgtaacca aaaataaaca gcagtagcag
    45421 cgggatcact accgcaatca gccagctact cggatcgcga acgatctgcc gcgtctcttt
    45481 aacgcacagc gcccgtacgc gacgccagga caggatcggg ttactcattg ctatgctcct
    45541 tatcccagtc gtggatcaac tgaataaagg cttgctccat ggtgggatcg ggttgctcat
    45601 cgttagccga ctgtgctttc aaatcgtccg gcgtgccgct ggcgattaat ttcccgcggt
    45661 acaccaggcc gatgcggtcg caatattccg cttcatccat aaagtgggtg gtgaccatca
    45721 ccgtgacgcc tttctctacc atgctgttga tgtgcagcca aaattcacgg cgggtgaggg
    45781 ggtcaacgcc ggaagtcggt tcgtcgagaa acagaatgtc cggttcatgc atcagcgaac
    45841 aggccagcgc cagccgctgt ttaaaaccta atggcagttc atcggtggcg tgggaggcga
    45901 tacttttcag gccgaacgcc tcgctcatgc gggagatttt ttcgttctgc gcccgaccgc
    45961 gtaagccata cacaccagag aaaaagcgta aattctgttc gaccgtcagg ttaccgtaga
    46021 gcgaaaattt ttgcgccata tagccgagat gctggcgcgc tttaccggaa ctctctttca
    46081 gatccatccc cagcaccagc gcctggccgg aagtcggcac cagcaaaccg cacatcatct
    46141 taaaggtggt cgatttaccc gcgccgtttg gccccagcaa accaaaaatc tccccacgtt
    46201 taacggcaaa gttgacgtga tcggtggcgg caaaatcccc aaatttcttg gtcagttctt
    46261 tcgcttcgat caccgtctcg ccgggtgtgc cttctaccgt atgtaatatt gcgcccagcg
    46321 gcgattccga ggttccggca ccgcccagca aatcaataaa cgcatcttca aaacgcggcg
    46381 tagtttcgtt gatgttgatt tccggcatcc cgtcggcatg gcgaatatcg tctggtgtgg
    46441 cctctttttt gaggatcaga cgtaccgatt tcccctgaat catgccgtcg ctgacctgcg
    46501 gcagtttcaa ggcgcgttgc aacagtttgc ggttgccctc gtgtggactg gtcatcagaa
    46561 agctgcgtcc ggccatggtt tgtgtcaggg cttttggtcc tccctgatac agcaactcgc
    46621 cttcgttcat cagtaacacg tcacggcact gctcggcttc gtcgagatac gaggtactcc
    46681 agaggattaa catcccttcg cccgccagct catgcaccat ctgccacagt tcgcgccgtg
    46741 agatagggtc aacgccgacg ccgggttcat cgagcagcaa cactttcggt tcgcccacca
    46801 gggtacaggc caggccgagt ttttgtttca tcccaccgga gagcttgccc gccaggcgtc
    46861 cggtaaacgg cccaagagac gtaaactcca gcaggcgagc aaaagtttgc ttacgtgcct
    46921 cgccggtgac gctgcgcaaa tccgcgtaca gattgaggtt ctccatcacc gtgagatctt
    46981 catacagacc aaatttctgc ggcatataac cgagcacggc gtgcagcgcg ccgtcgtttt
    47041 tgatcggatc aaagccaatc accgtggcac tgccgctgtc gggtttcagt aatcccgcca
    47101 acatccgcat cagcgtggtt ttacctgcac cgtccggccc caccaacccc gtcacataac
    47161 cggcgtgaat ggtacaatcg agcggcgcga cggcgggctt gtccatgccc ggaaagcgtt
    47221 tttccaggcc gttcagcgtg ataacggcat cattcatgtc ctgcctcgtc accgaattgt
    47281 accgtcactg gcattccctg gcgtaacgca tcatcggcgt cggtcaccac aatacgcagg
    47341 cgatagacga ggtcggtacg cagatccggc gtttcgacgg ttttcggggt aaattcagca
    47401 gtcggcgaaa cgaaaccaat ctgcccgtga tacggcttgt ccgggcgacc atcggtataa
    47461 agcagcactt tgcgccccgg ctgggcctgg tcaagattac gttcatcaac ataagcgcgc
    47521 acccacaccg gacgcgttag tgaaacggta aacaccgtgc caccttcatt gaggaccgtg
    47581 cctggctcca ccgcgcgcgt taacagcgtg ccatcagacg gggctatcaa cgttgagtcc
    47641 tgtaaattca actccgcctg cgccagttgc gcctgcgcct gttcgaggct ggctttcgcc
    47701 tgagcgatgt cctgttcacg gttaccggaa cggtactgac gcaatttatc ctgtgctgat
    47761 ttcagcgttg cctgcgcctg gtcgcgcgag gagcgggcat tttccaggtc atttgccgaa
    47821 atagtgcggc ttttccacaa cccttgctgg cggttataga agttctgcgc atagtcatag
    47881 gcggcttgcg cctgtttcac cgctgcggcg gcctgagcga tttcttcatc gcgatacccg
    47941 gcaagcatca ggtcatactg cgcctgtgcc accgaaacac ccgctttcgc ctgcatcagg
    48001 gcaatctcat acggcttgtg atccagttcg cccagcacct ggcccgcttt gatagcatca
    48061 ccttcgtcca ccgccagcga ttcaacgcgc cccccaacac ggaaactaag atttaccgta
    48121 cgaatatcca cgttgccata cagcgtcagg ccgttatcct ggcggctttg ataccaccag
    48181 tagcctccgg caaccacggc ggcaagtacc actaccgcca atccgatcac gacaggtttt
    48241 ttcatcacta caaactcctt tgcgataatc cttgcaaaat caggtcgata tgacaggtca
    48301 ccgtctggtt gatcagttcg gtcttttctt catcgaacgc ggtccagccg gtacgtaaca
    48361 gaattgtttc tttgccaaga cggaacgcca gaatctcacc aatcaacgca tgggtatgaa
    48421 ggatcatgcg ggtgtcattg gcgtcgcagc cggtccaggc ggcaatcagg cgtgtcaggt
    48481 ggctgtgtag cggactaatc acctgttcgt gcaccaggtg gtaggctgcc gtgggagaga
    48541 gctgctcacg ggagataaac ttgctgaggt tgacggtgtc atcctgggtg agcagcttaa
    48601 tcatgttcct gcaggcgcga aggatcagtt cacggatggc agcccgatca ggctgtggtt
    48661 gcgcgaacaa gcgttcggct tcctcggcat gcggacggaa ctgctcgcca ataaaatcgg
    48721 caatccactg ggcgcaggcg aggtacaaat cttctttcga accgaagtag taggtgatgg
    48781 cagcgatatt ctgcccggcc tgggcggcta tctcgcgagt ggtggcgttc attccatatt
    48841 caccaaactg cgccagtgcg gcagcaatca gctgtttttt cgcctgttca cccttgattg
    48901 tcatggcagg attattcatc gcacagtcca ttcttaatca aatgattgat taagattatg
    48961 actccatagg ggagttgtcc agtatggcta agaattttag caacgccagt cacagggata
    49021 atttatgcgc tgcgtcacaa aaactgctac actccgctcc ctcatgacat tgtggttttt
    49081 gtcattttcc ttttcagtat ctccctgaaa actacaccgg taacggtcgg ggcggttcgg
    49141 agtagttatg tctttcgatt ctttgggttt aagccctgat atcctgcgcg ccgttgccga
    49201 gcagggttac cgtgaaccca cccctattca gcagcaggcg atccctgcgg tgctggaagg
    49261 ccgcgacctg atggctagcg cccagaccgg caccggcaaa acagcgggct ttacgctgcc
    49321 gctgttgcaa cacctgatca ctcgccagcc gcacgccaaa gggcgtcgtc cggtacgtgc
    49381 gctcattctt accccgaccc gtgaactggc ggcgcagatt ggcgaaaacg tccgtgatta
    49441 cagcaaatac ctgaacattc gttcgctggt ggtgtttggt ggtgtgagta ttaacccgca
    49501 gatgatgaaa ctgcgtggcg gcgttgatgt gctggtggca accccgggac gtttgctgga
    49561 cctggaacat cagaatgcag tgaagctgga tcaggttgaa atcctcgtcc tcgatgaagc
    49621 tgaccgcatg ctcgacatgg gctttatcca cgatatccgt cgcgtgttaa caaaactacc
    49681 tgcgaagcgc cagaacctgt tattctccgc gaccttctct gacgatatta aagccctggc
    49741 ggaaaaactg ttgcacaacc cgctggaaat cgaagtggca cgccgcaata ccgcgtctga
    49801 tcaggtgacc cagcacgttc actttgtcga taagaaacgc aaacgcgaat tgctgtcgca
    49861 catgattggg aaagggaact ggcagcaggt gctggtgttt acccgtacca aacacggcgc
    49921 taaccatctg gctgaacagc tcaataaaga tggcatccgt agtgcggcga tccacggcaa
    49981 taaatcgcaa ggtgcgcgta ctcgtgcgct ggctgatttt aaatcgggcg atattcgtgt
    50041 actggtggca actgacatcg ctgcgcgcgg cctggatatt gaagagctgc cgcacgtcgt
    50101 caactatgaa ctgccaaacg tacctgaaga ttatgtccac cgtatcgggc gtaccggtcg
    50161 tgcggctgct accggtgaag cgttgtcgct ggtgtgtgtt gatgaacaca aactgctgcg
    50221 tgatatcgaa aaactgctga aaaaagagat cccgcgcatt gcgattccgg gctatgagcc
    50281 ggacccgtca atcaaagccg aaccgatcca gaacggtcgc cagcaacgtg gcggcggcgg
    50341 tcgtgggcaa ggtggtggtc gcggtcaaca gcaaccacgc cgtggggaag gtggcgcaaa
    50401 atctgcaagc gcgaaacctg cagaaaaacc gtctcgccgc ctcggcgatg ccaaaccggc
    50461 aggcgaacaa caacgtcgcc gccgtccgcg taaacctgcc gctgcgcagt aatcttttat
    50521 gccgggctat gcccggcatc aggctgatga acaaacgcaa aactgcctga tgcgctacgc
    50581 ttatcaggcc tacgtgaact ctgcaatata ttgaatttgc atgcttttgt aggccggata
    50641 aggcgtttac gccgcatccg gcatttcaca acaagcactt gtcagcaatt tgagaacacg
    50701 ggaaaaaatt tatctgtttt accgcccata agccaccgag acgttacttc tctatagcca
    50761 attgttcgcg caactccatt aaaaggtagc ccagtcgatt cttgccctta ccatgaccac
    50821 cgtctcccca gtaagcatcg ttttccgtat gctcaaccag ttttgcgggc gcggttgcca
    50881 gcaagagcgc acgcagttct gcatgctgtt cgaatttagc gcgaagtgct tttcgcatca
    50941 cctgttcttt gaccgactcc cagtttttac gcagaggctt agaacgatcg cgccccatgc
    51001 gtgcggcgac cataggggaa gaaacccgac ggatctcttc gcggtatttt tcatcaagga
    51061 atttttgtgc ctgaaaatag tgttctgagg tgggccaggt tttcccgtca accttgatgg
    51121 gccaggcggc aaagttagaa aaatcaccgt agtcatcgct ggtgctgtag aaatttatga
    51181 tggtgtcttg catgacgtgt tggatccttt gtgctcgaac gggcattaaa ccgcattatg
    51241 ttggtggtta ttgcgagccg ctttccagaa acagaaaaac cattacccct gaaaaccgaa
    51301 aaatgccaca atattggctg tttatacagt atttcaggtt ttctcatggc attaaccgcc
    51361 gcgcttaaag cgcaaattgc cgcctggtat aaggcgcttc aggaacagat ccccgacttt
    51421 attccccgtg cgccgcagcg gcagatgatt gcggacgtcg ccaaaacgct ggccggagaa
    51481 gaagggcgac atctggcgat tgaagccccc accggcgttg ggaaaacgct ctcttatttg
    51541 attcccggca tcgccattgc ccgcgaagag caaaaaacgc tggtggtgag taccgccaac
    51601 gtggcattgc aggatcagat ttacagcaaa gatttaccgc tgctgaaaaa gatcattccc
    51661 gatcttaaat tcactgccgc ttttgggcgt gggcgctacg tttgtccgcg taatctgacg
    51721 gcgctcgcca gtactgaacc cacgcaacag gatctgctgg cgtttcttga cgacgaactg
    51781 acgccgaaca atcaggaaga gcaaaaacgt tgtgcgaagc tgaagggcga tctcgatact
    51841 tataaatggg atggtctgcg cgatcatact gatatcgcta tagatgacga tctctggcgt
    51901 cgtttaagta ccgacaaagc cagctgcctc aaccgcaatt gttactacta tcgtgaatgc
    51961 ccgttttttg tcgctcgtcg ggagattcag gaagcggaag tggtggtggc aaaccatgcg
    52021 ctggtgatgg cggcgatgga aagcgaagcg gtattgcctg acccgaaaaa tttactgctg
    52081 gtgctggacg aaggccatca cctgccggat gtggcgcggg atgcgcttga gatgagcgcc
    52141 gaaatcaccg cgccgtggta tcggctacag ctggacttgt tcacgaaact ggtcgctacc
    52201 tgcatggagc agtttcgccc gaagaccatc ccaccgctgg cgatccctga acgtttgaat
    52261 gcgcattgtg aagagttgta tgagcttatc gcctcgttaa acaacattct caatctctac
    52321 atgcctgccg ggcaggaggc agagcaccgt tttgcgatgg gcgaactgcc agatgaagtg
    52381 ctggagatct gccagcggct ggcaaaactc accgagatgc tgcgtggcct ggcggagtta
    52441 tttcttaacg atttaagtga gaaaaccggc agccatgaca ttgtacgtct gcatcggttg
    52501 attttgcaga tgaaccgcgc gttggggatg ttcgaggcgc aaagcaaact ctggcggctg
    52561 gcttcgctgg cgcaatcttc cggtgcaccg gtgaccaaat gggcgacgcg ggaagagcgc
    52621 gaagggcagc tacacctctg gtttcactgc gtgggaatac gtgtcagcga tcagctggaa
    52681 aggctgctgt ggcgcagtat tccgcacatt attgtcacct ccgcaacctt gcgttcgctg
    52741 aacagttttt cgcgtttgca ggagatgagt ggtctgaaag agaaagcggg cgaccgtttt
    52801 gtggcgctgg attccccctt taaccactgc gaacagggca aaattgttat tccccggatg
    52861 cgcgttgagc cttccatcga caacgaagag cagcatattg ccgaaatggc ggcctttttc
    52921 cgtaagcagg tggagagcaa aaaacatctc ggtatgttgg tactgtttgc cagcggacgg
    52981 gcgatgcagc gctttctcga ctatgtgacg gatttacgtc tgatgttgct ggttcagggc
    53041 gatcagccgc gttaccgttt agttgaactg caccgcaaac gcgtcgccaa cggtgagcgc
    53101 agcgtgctgg tgggcttaca gtcatttgcc gaaggacttg atttgaaagg tgatctgctc
    53161 agccaggtgc atatccacaa aatcgctttt ccgcccatcg acagcccggt ggtgatcacc
    53221 gaaggggaat ggctgaaaag cctcaaccgc tatccgtttg aggtgcaaag cctgccgagc
    53281 gcctcgttta acctgattca gcaggttggg cgactgattc gaagccacgg ttgctggggc
    53341 gaagtggtta tctacgacaa acgcttgctg accaaaaatt atggcaagcg actactggat
    53401 gcattaccgg tatttccgat agagcaaccg gaagtccctg aaggtatagt taaaaagaaa
    53461 gaaaaaacga aatccccacg ccgtcggcgg cgttaatgat gtgagtcagg taaggagtcg
    53521 taaatggact atcgcaaaat cattaaagag atcgggcgcg ggaaaaacca cgcgcgcgat
    53581 ttagaccggg atactgcgcg cggtctgtat gctcatatgc tcaatggtga agtccctgac
    53641 cttgagttgg gcggcgtatt gattgcgctg cgtatcaaag gagaagggga agcagagatg
    53701 ctcggctttt acgaagccat gcaaaatcac accatcaagc tgacgccgcc agcaggcaag
    53761 ccgatgccga ttgtcatccc cagttacaac ggcgcgcgta aacaggccaa cctgacgccg
    53821 ttgttggcga ttctcctgca caaactcggt tttcctgtgg tggttcacgg ggttagcgaa
    53881 gatccaaccc gcgtgctgac tgaaaccatt tttgaattga tgggtattac gccaacgttg
    53941 cacggcgggc aggcgcaggc gaagctcgac gaacatcaac cggtgtttat gccagtcggc
    54001 gcgttttgcc cgccgctgga aaaacaactg gcgatgcgct ggcggatggg cgtgcgtaac
    54061 agtgcacata ccctggcgaa actggcgacg ccatttgccg aaggtgaggc gctgcgtctt
    54121 tccagcgttt cgcatccgga atacattgga cgcgtcgcga agttctttag cgatatcggc
    54181 gggcgggcgc tactaatgca tggtactgaa ggtgaagtgt atgctaatcc gcagcgctgc
    54241 ccgcagatca atctcattga ccgtgaaggg atgcgggtgc tgtatgaaaa acaggacact
    54301 gctggtagcg agttactgcc acaagcaaaa gatccggaaa ccacggcgca gtggattgag
    54361 cgttgccttg ctggcagcga accgattccc gaatcgctga aaatccagat ggcttgctgc
    54421 ctggtggcta cgggtgaagc ggcaactatc agcgacggcc tggcgcgcgt taatcaggca
    54481 ttttaattct tttctcagcc ggatgagcca tgtcatccgg cttttacccc accgcaatat
    54541 gaaattcctg catctttatt gaccttccca cgcccggcgt gcagcataaa aatacaacaa
    54601 acacataaca taaacaggag ttaaccatgg aaagtggtca tcgctttgat gctcagacgc
    54661 tgcacagttt tattcaggct gtatttcgtc agatgggtag cgaggaacaa gaagcgaaat
    54721 tagttgccga tcatttaatc gcggcaaacc tggcagggca tgattcacat ggtattggca
    54781 tgatcccaag ctatgtacgc tcctggagtc aggggcacct gcaaattaac catcatgcca
    54841 aaaccgttaa agaggcgggg gcggcggtca cgctcgatgg cgatcgcgca tttggtcagg
    54901 tcgcggcaca tgaagcgatg gcgctgggga ttgagaaagc gcatcagcac ggtattgccg
    54961 ccgtggcgct acataactcg catcatatcg gccgtatcgg ttactgggcg gagcagtgtg
    55021 cagcggcggg gtttgtctct atccactttg ttagcgtggt cggtattcca atggtcgcgc
    55081 cgttccacgg tcgcgacagc cgctttggca ccaatccgtt ctgtgtggtt ttccctcgta
    55141 aagataattt cccgctgttg cttgattacg ccaccagcgc cattgcattt ggcaaaaccc
    55201 gcgtcgcctg gcataaaggc gtccccgtgc cgccaggttg cctgattgac gttaacggcg
    55261 tgccgacgac caatccggcg gtaatgcagg agtcgccgtt gggttcgctg ttgacctttg
    55321 ccgaacataa aggctacgcc cttgcagcga tgtgtgaaat tcttggcggg gcgctttccg
    55381 gcggtaaaac gacgcatcag gaaacgttac aaaccagtcc cgatgccatt cttaactgca
    55441 tgaccactat catcatcaac ccggaactct tcggcgcgcc ggattgtaac gcgcagaccg
    55501 aagcctttgc cgagtgggtg aaagcctcgc cgcatgatga tgataagccg attttgctac
    55561 cgggcgagtg ggaagtgaac acgcgtcgcg aacggcagaa gcaggggatt ccactggatg
    55621 cgggaagctg gcaggccatt tgtgatgcag cgcggcagat tggtatgccg gaagagacgt
    55681 tgcaggcttt ctgtcagcag ttagccagct aaaaaaaagc ccgtccagtg gcggacgggc
    55741 aaacaagggt aacataggat caatgagggt tagagcatat gcgtctgtcg gcaaacagac
    55801 agggaaatac ttgtgctgga cgtagcgtaa acgcctgatc cgtccaacgg ttcggatttt
    55861 gtaggcctga taagacgcgg tagcgtcgca tcaggcatct gttgccggat gcggcgtaaa
    55921 cgccttatcc gtcctacgaa ttacttataa attaccgcag taccgcttaa tttattgttg
    55981 ttggtggcgg aagtgatgct gtatccactg gcaccggctg ccgcggcttt ctcagccagt
    56041 ttcgcttcca gggcatcgag ggtggatgcg ccatcggcag aaaccacgcc gattttattc
    56101 atgttctgtg cctgggatgc cgttaccggt tccgccgcga acacgccaaa tgacagagtt
    56161 gaaagagcca tagcagcaac aacagtattg atagttttca taattaatct ctcgcaggtg
    56221 atttttgtat aagtgacgtt gtttcgtcga tgtgatgagt atcacgtttt tttacgagag
    56281 ataaaatcga agagaattga ccgccttgtt caaataaatt gattgatatc taacctactg
    56341 ataaaccatt tatttgttgt acttatgaac ttgttttata ccgcgtggca gtcacagcag
    56401 cgttaaaggc acggaatgac acgcaaaata caaattatac tcgctatgca tctcgccagt
    56461 tgtagttaac gtaactggct gtctttcgaa cctctgcgat tatatcctgt ataagctggt
    56521 ttttgtaaat ctttctcctg ctgacaatga atacataagc gcacgccagg aatggcttcc
    56581 cgacgggcct gcgggatggg ggcaccgcac tcttcacatt catccaggct ttcgccgcgc
    56641 ggaatttcac cccgagcgcg ggcaatcgca tcttcaattg tactgttgat ctgttcgttg
    56701 acggcgtcat cgttagccca accggatgcc atatcgacct ccccatatca atacttgtac
    56761 agttaagtgt agctaatcca gggacgaact cgggcagttc aagcatcaga tctccgacca
    56821 ttcccgcagc agattatgat aaagattaag cagcgacagg atctcttcac tttcgccgta
    56881 gcggcttttc agcgactgaa tattgttgtc cagttcaaac agcatggcgc gctttttatc
    56941 atcgcggatc atcgactgga tccacataaa tgatgccact cgtacgccgc gggttacggg
    57001 tgtcacgcaa tgcaggctgc tggagggata caacacgaga tcgcctgccg ggagttttac
    57061 ccgatgttgt ccgaaggtgt cattaacgac cagttcgccg ccgtcgtagc tttgtggatc
    57121 gcttaaaaac agcgtggcag aaaggtcagt acgcatccag ccgttttgtg gatggctgcg
    57181 tactgcgcca tccacatgga aaccataggt ttcattgttc tgatagcgat taaacagcgg
    57241 cgtggaaagg gtacgcggca aggccgcggc aaagaataaa gcatgttggt taaccgcgtt
    57301 cagcacctca ttttgcaggg cggcgtataa cgtgctgcgg gtgtcgacct gttgattgtt
    57361 cttaacttgc gcaccttgtg cgccggtggt gacgcgtcca tccacccatt cggcttgttc
    57421 cagttgttcg cgaaaacgag cgacgtcctg tggcgataac acgccgggaa tgtggtacat
    57481 catacaattt ctccaaaaag tggggcctgc gccccacatc tgaatcagaa atgcatattg
    57541 gctgtgagca agaaggttct tggctcgccc gggtgataac ggtagccgct cttgttgatt
    57601 gaggcgacgt aatcggtatc aaacaggttg taaacgttta gctggaagtc gagattgcga
    57661 ttaactcgat accccagttt ggcatcggcg acccagtaac cttcggtaaa cgctggcgtt
    57721 cccaccgcgc cgtctgaacc tttatgcata ctgccgatat agcgtgcgcc cgcgccaaca
    57781 gagatatcgt cggttgcctg atattggctc cataaggtga aggcgtgctc cggggtatac
    57841 ggcagcgatg aggaaccatc ctgggcaaca tctttgccgt ttttgatggt tgctttttgc
    57901 tgggtatagc cgccaatcac ctgccacgcg ggagtgatat tcccggccac ggatatctca
    57961 tagccttcga cgcgtttctt accgtattgc gagtaagttc cgtcatcatt ttgctcaact
    58021 tcattttcga tatcagtgcg gaacagcgcg gcggtgagca acagacgttt atccagaacc
    58081 tgccatttgg tgccaatctc gctggtgttg gctttttgcg gtttaaaatc ggtgcggttg
    58141 gcactgttac cgctgccaga ctgcgcaagg gcgaagttgt tgccgcccgg aggctgctgg
    58201 gaaacggcat agttaatata gacattgccg ttttccgtca ggtgatacag cgccccggct
    58261 ttccagttca tcagattgcc cgacttggcg gtgtcgacgg tggtgaccgg agaacctttt
    58321 gccacaccag ttgggcaggt gatggcaccg cgtccgctgc cgccgcaggc ggtggcactg
    58381 tcatattcag tatgataatt atccagacgg atcccgccgt tcagctcaaa atcacgggtg
    58441 atttgcagcg tatcaaaggc gtaaattgcg aaggtatccg tctgaccatt ggcgtttgcg
    58501 ccgttgcgcg tcaggccgcc gggatgaatg ctgctgtcag gatgataaat atttaccgcg
    58561 ggtaacgtca ccggattaac gccgtagtta gtctgcgttt cacgggtaaa ttccacgccg
    58621 gtactgacat catgaccgat agaaccggta tagaacgtcg aggtcaggtt ggtctggttg
    58681 gtgagaattt tattactcac atctttggta ttcgccgtgc gtgaccaggt ccagctattc
    58741 acatcgctgg tgggctgagt aatattcgac gccccgccca taatcgccgt catcaggtaa
    58801 tcctgcttta cgcgcgacca acgggtagta ttgcgaatgg tggtgttatc gttgatgtcg
    58861 tgctcaaaac gcatggtggc ggtgtcggtg gtcgaatcgt cgtaatcgga atccgtgccg
    58921 taaaagttat gagtatcaac ttttccggaa tgattcaggg ccgccgttcc cgcagatggg
    58981 gcagaatagc ccggcaaacc gatggtcgga atgccgccgt ctggcgtgtt gtgctgggtg
    59041 acatgcagat aattaagata caaacgattc gctgtaccaa ggccaaaagc gacagaaggg
    59101 gcgacgccgt aacgctcatt tttgactttg tcgcgtccgg catcgtgcgt tttttcgccc
    59161 attacattca ggcgcaccgc ggtggtatca ccaatgacct gattgacgtc cagcgtgccg
    59221 cggcggaacc aggcgctgcc aatactggcg gaggcgtcaa tgccggaatc attgcgcggc
    59281 tgcttgctga tcatattgat cgagcctgtc ggtgcgctgc gcccgtagtc ggtgccggac
    59341 ggccctttaa tcacttcgac ctgctcggta ttgaaggtgt cgcgcgagac gctgccgata
    59401 tcgcgaatgc catcaatata aatactgtta gaggtatcgg caccacgcat ataaatggcg
    59461 tcgccagtgg tggagttacc gttctcaccc gcaaaaaacg cacccacgcc ggggacgttt
    59521 ttgagcgcgt cggtaaggtt ggttgcgccc tgatctttaa tcacttgttc agaaattacc
    59581 gtcatcgtgc gggtagtatc cgctaccgga cgcgagaatt tcggatcggc agattgttgt
    59641 ggcgcataaa gcgaaggcgt tgatgcttcg acaaccagcg tgtcatccgc gttagtttgc
    59701 ccttcggcgg cgagtgcctg agccacaggc gtgatgccaa tacaaagacc ggcaaagaac
    59761 gtgagcgaat gaaattgtct ggcagggaaa ttgcgattgt tttccatttt gcaggtgact
    59821 ttttcttata tgttgaaatt ttcactgcca cgagaaagcc tctctgcgga agcgatgcca
    59881 ctgttaatcc cgtgatagtg ctcgtgaaag tgataataat tttgataagc attatcactt
    59941 ggagcgattt tctatcaccc attgcgcgaa aaagaaatac atttatttac attgagttca
    60001 tatttgatgt ttttttgatt acaaaacaga cgaaaactgc atccagaggc gaatgcagtt
    60061 acgttggtgg ggttatttgt agatggttgc agtaccgaac atctggtcat ttccgcctgc
    60121 ggaattaatg acataacctt tcgcgccttg ttcgcgcgct ttttctgcca gtttatcctc
    60181 cagatcgctt aggtttgatg cgccagttgc cgaaacggta ccggcgggcc gtagctgacc
    60241 gctgtccagg ttactcatcg gttgcgcggc ataagccgtg agagagattc cgctcaggac
    60301 ggtggcaatc agtagtgtga ggcacttttt cataatgaca tcctcataaa tacaacgggt
    60361 agtgcctgat aagtgtaggt cgcctgcgcg atgcaaatga cgcaaaaaat tgacagagat
    60421 gtgcttattt tttgaacgat atatttttac aaaataagac aaatcaatga catgcataat
    60481 gctgattttt atgatgaatt gccataaacc atagccatgt taaggttttg gggaatgata
    60541 aacgcagcca gatatttacc ctgtcgcgtt atgcgggtat cttacgccgc tgcttaaagg
    60601 agaatgctat gtccgcccag aaaccggggt tgcatccgcg caaccgtcat cacagccgct
    60661 acgatctcgc cacgctttgt caggtcaatc ctgaactcag gcaattcctc acgcttacac
    60721 ccgccgggga gcaaagcgta gactttgcca atccgctggc ggtgaaggcg ctcaataagg
    60781 cgttgctggc ccatttttac gccgtagcga actgggatat ccccgacggt tttctctgcc
    60841 caccagtacc gggccgggcg gattatattc atcaccttgc cgatttactg gcagaagcaa
    60901 gcggaacaat tccagcgaat gccagcattc tggatatcgg cgttggtgcg aactgtattt
    60961 atccgctgat tggcgtacat gaatatggct ggcgttttac cggtagtgaa accagcagcc
    61021 aggcgttaag cagtgcgcag gcgattatca gttctaatcc ggggcttaac cgcgccattc
    61081 gtctgcgtcg gcaaaaagag agtggggcga tttttaacgg catcatccat aaaaacgagc
    61141 aatacgacgc gaccttgtgt aacccgccat tccacgattc cgccgctgcg gcacgggcag
    61201 gtagtgagcg taaacgccgt aacctggggc tgaacaaaga cgatgcactg aactttggcg
    61261 gccagcaaca ggagttgtgg tgtgaaggcg gtgaagtcac ctttatcaaa aagatgattg
    61321 aagagagcaa aggcttcgcg aagcaggtga tgtggtttac atcactggta tctcgtggtg
    61381 aaaacttacc gccgttgtat cgtgccctga cggacgtggg cgcggtgaag gtggttaaaa
    61441 aagagatggc ccaggggcaa aagcagagtc gctttattgc ctggaccttt atgaacgacg
    61501 agcagcgccg ccgttttgtc aatcgccagc gttaaagcgt tggttccccc ggcggtaacg
    61561 gttcagccgg ggtcgcgccc ggagcaggca gcacctgata agtctgcact ggcgcgcgaa
    61621 cgcccgccag gtcgaaatgt tttttcacct ggctgtcgag ggcaaagcgt accgtccact
    61681 gtttgagtgg cagcgtggtg aacgaaacac gcagtgtaaa cgcggtattg cttaagccga
    61741 caatcccggc aaaattcggt tcaccaataa tcagcccgcg aatttcttcg ttttccatta
    61801 attccgctac cgcatctttc agtgcctgat tggctttatc agcatcttca tggcgatcaa
    61861 catcataatt tgccaccacc gaaccaatgc cgcggacaaa gttagcaaag gtggttatcg
    61921 aagaccacgg aatgatgtga tacgccccgg tatcctgtcg tacgcccacg gagcgaatcg
    61981 acatccgttc cactgtgccg gtcaacggcc cgatagtcac caaatctcca gtgttcatgc
    62041 cgttttcaaa ctgaataaat accccggtga taatatcttt caccagcgtt tgcgaaccaa
    62101 acgagatagc cagacctaat gccccggcac ctgccagcaa tggcgcgata ttgacgccga
    62161 tttccgacaa cacaatcatg atggtgatgg tactgataat caccgccagc gcgttacgaa
    62221 acagcgtaag cagggtacgc gtgcgggcgc tgggtagcgg gcggccatga atatccgaag
    62281 ccagccggtt ttcgatcaaa ctggcgagca ccgtccagcc aaccgccgag aagaaaagaa
    62341 tgagtgcgat acggatcagg atatctacgg ttttctgccc cgcgccgttt tgcagccagt
    62401 tccagaaatc gaacaatccc catgcgctca acagcaacat taccgccacg cagactgtca
    62461 gaatacgcgc cgttttcagc gccgccgaca gccagccatt caaccgtttt tgcagctccg
    62521 gatagttacg ctgagtatgt ggcgagagag tgatggtttt cgccagccag cgggaaaaca
    62581 taccggaaac aaacgctgcg ataccaataa tcgccaggct gcgcaccgtt gcacccatca
    62641 taaatttcag gctgttgccc ggatcgaaca acgaaaagaa aaacagcacg ataaaatagg
    62701 cgcttgccag ccagtgccac accagcgcaa aggcgcggat aaacaggctg aaaaaggcca
    62761 gcgaatgctc cgcgaagttg agcaaatgct gggtaatctc ttttttatta cgaaagatca
    62821 ggtacaacgc ccagacggtc atgcacagca taatgatgac gttcgccagc gcacctatct
    62881 gtacattcac ctgattagag ataatcggca cggccacaat caggccataa cctatcaaac
    62941 tgcttaacca gctcaggcga cgactccagt aacgggcgct ctcgtcctga atcgtgaacg
    63001 ggcgcagctc cgccacgttt gggcaaaaaa tcaggcgtag tacggctttg aaaaattcaa
    63061 tgagggcaaa ggcgttgaga aacaaacttt gttggaaagc gatggtgcga ctgcctgcat
    63121 tcaggttgtc gcttaatacc tggccgacaa ataatgtcag ggccagtaac agcaggtcga
    63181 taataaacgc cccgataatc atcgccggaa gctgcaacca gttgctgcgc tcacgatttt
    63241 tttgccgcgc ccactgaccc attttgcgat acagcggcag tgcgcacagg cgaatcagcc
    63301 agtaaaaacc aaacactaat accgctaaca ttgaaaaatg ggtcagcgca ttgctgaagg
    63361 tttgtggatt aaacggctta tgcggggagc cggtgatatt gcgataaagt tgcccgaagc
    63421 gggcggaaag ggcttcacca taatggcggc tgacttcggt gaccttttgc agcacggttt
    63481 gctcttcgac cagcgtcggc ggcactattt ttggtaccgg ttcagcaggg ggcgtagcgg
    63541 caacggtgcg caactggtcg atcaactctt tacgcgaggt gtcattatcc agcacatccg
    63601 ccagtgcgcc ataggccgct tttttttgtt cgatatccgg ttccggggcc ggttcagtcg
    63661 ttgagtccgt tgtcgttgtg gttgtaacgc cgggtatgga taccgcgtgg gcaggtgcgc
    63721 ccagcaggca gaagaggatg aacaggatcc accgcatgac tcctccagtg agaaaataga
    63781 gcaaaaagat aagtatagat gctggaggag gggcgatttt aaatgagagg aatctggtgt
    63841 gcctcccttt cgggtgaaag ggaggaaggg atattaagca ggttgctgac aacgtgcggg
    63901 cttttttgcc ggatgcggcg tgaacgcctt atccgtccta caagttcatg caattttaat
    63961 aagttgccag atatcctgta ggcctgataa gcgtagcgca tcaggcaatg tgtcttatta
    64021 agagacgtgc tgcaaaaatt cctgcaagcg ctggctcggc gggttcttga tcaacacctg
    64081 cggattgcca tcttccgcaa tccggccttt gtcgataaag atcagccgcg aagctacttt
    64141 ctcggcaaaa ccgatttcgt gggtcacgat caccatcgtc atcccttctt cagccagatc
    64201 ctgcataacc ttcagcactt catggcgcag ttccgggtca agagcggaag tcggttcatc
    64261 aaacagcatc attttcggct tcaccgccag cgcgcgggca atcgccacac gctgctgttg
    64321 accaccagaa agttcggaag ggtagtgatg tgcacgttct gccagaccga ctttcgccag
    64381 cagctcacgt gccagttttt ccgcctcttc tttgttcgcg ccacgcacgc gtagcgggcc
    64441 aaacatgacg ttttccagcg ctgtcagatg cgggaagagg taaaactgct ggaacaccat
    64501 acctgcttcc tggcgaatca ggcgctcgtc aactttcgga tcgttaacct tcaggccatc
    64561 gacaatcaga tcgccggagg tgatttcttc cagtttgttg atgcagcgca gcagggtcga
    64621 tttaccggaa ccggacggcc cgataatcac cacgacttcg ccctgggcaa tgttcaaatc
    64681 gatattgtgc agcacctggg ttgggccaaa gtgcttggag acgtttttaa attcaatcac
    64741 aggattttca tccttctttc cagacgacgc agaataaagc tcagcaccag ggtaataatc
    64801 agatagaaca ccgccacggc gctccagatc tcaagggcgc ggaagttacc ggcaataatt
    64861 tcttgcccct gacgggtcag ttccgccacg ccgatcacaa taaacagcga ggtgtcttta
    64921 atgctgatga tccactggtt acccagcggc ggcagcatac gacgcagtgc cagcggtaaa
    64981 atgacgtagc gaatggtttc ccaacgtgaa agaccgagcg ccagtcctgc ttcacgaaaa
    65041 cctttgtgga tagacagcac cgcaccacgc gtgatttccg caatatacgc gccggagttg
    65101 atcatgatgg tgaccaccgc cgcagtaaat gggtcgatgc gtaagtcgtt aaacgccatc
    65161 ggcagggcga aataaataaa catcacctgg acgacgatag gtgtgccgcg gatcacttca
    65221 ataaagacca gcgcgacgtg gttggctatc caacctccga aggtgcgtgc aaaacctgcc
    65281 agcaatccga ttaccagacc gcctgccaga ccgaggaccg aaatccacag ggtcattttg
    65341 gcaccttcaa tcagaagcgg aatggcaggc cagatggcac tccagtcaaa ctgcatatgt
    65401 tgttcctgtt accgtggtgt aaataatcaa attcagggta attaatggcc ccggagcggg
    65461 tttgcgcccc tcaccctaat cctctcccca taggggagag ggaactgcca gtgcgtttta
    65521 caggtgtagc gttattattt cggttcagta ccgaaccatt ttttgtagat ttcgttgtaa
    65581 gttccgttct cgcgcagggt tttcaacgcg ccgttgactt tgtcacgcag ctcgtcgcta
    65641 cctttcggga acgcaatacc gtattgctgc gcttccagag agtcacctac cgctttgaac
    65701 tgaccgttac cggcggtttt gatgaagtac agaatgtttg gcgtatcgtg cagaacggcg
    65761 tctgcgcggt tggtgcccag ttccatatag gcgttatcga tgttcgggaa ctgacgcaga
    65821 tctttagttt tgatgtttgc tttcgcgtaa tcaacggagc cagtaccgct cttcacagca
    65881 accactttcc cgtcgagatc tttcacgctt ttcacatcgt tattgttagc tttcaccatc
    65941 actaacaggc cgcttttgta gtagccgtca gagaaatcga tcgctttttt acgctcgtcg
    66001 gtgatggtaa tgcccgccag cgccagatcg acgtttttgg tttgcagtgc cggaatgatc
    66061 ccactgaaat ccatcggctt cagttcgtaa tccagcttca gctctttagc gatggcagcc
    66121 cacagatcaa cgtcaaagcc cacatattta tcgccctgtt taaattcaaa cggaacgaag
    66181 gcggtatccg tcgcgacaac taatttttta tccgcggcat gagaagaaac cgcaaaagcc
    66241 agggtcagtg cagccagtga aacttttaat acagacttca tagcatttcc ttttttctat
    66301 ccacgggacg atcccctgcg tgacattcac atatatgaaa aaatcgtgcc agttttgcaa
    66361 ctccttgatt tttcgagatg cggcaaaaac gtgatgcacg atttataggg caataccctg
    66421 aagatgcacc attctggggc accaatctgg tgcgctaaaa ttgtgcactc aacacagtga
    66481 ttatttagcg taaaacctga tgaaaaaaca atctttatgt aacgattgtg tgatgatgtg
    66541 gatacaaaaa atttacttaa tcagctggag atagcagatg gatgcactaa ataagtgcgt
    66601 tgaggtgggc tgcaaaacaa aacggcctcc tgtcaggaag ccgcttttat cgggtactaa
    66661 agttctgcac catcagcgat ggatttattc gatgttagac tcgataaacc acaggaattt
    66721 atccaggtcg cgagacgcgg cggtcaggat atctgcggtg tcgtcatctt tcgcttcgcc
    66781 aatcgctttg cgtacgtcat tagcgacgat tgcgtaacgg tcagccagtt ctttcaggtg
    66841 atcctgaacg ttgtggatgt ccagcgggta acttttcagc ggggttttgc tgttgataac
    66901 ttgagtggtc cccagagcta caccgcccag ctgcactgca cgttctgcca tggtatccag
    66961 atgatcgatc agtgcggtgc ggaagccatc cagcatttca tgtacggcaa tgaagttagc
    67021 gccgcgcatg ttccagtgcg cttgtttggt aatcaaagaa agatcaataa actggataac
    67081 ctggcgattc agcaactcta ctgttgcttt tttctcgctg tcggagacat cgttgcgggt
    67141 ataaagcaga ttggtcgctt ttgatttaac taatttagcg gtactcataa tttcatatcc
    67201 tcttgatgtt atgtcccagt aattaacgag actaagtata gcaccggcta tgtgttccgc
    67261 tattctggct gttcctatca cactaatagt ggtaacaagc gtgaaaaaca aaactaataa
    67321 agattcaatg agttagatat attgataaga acaattctta tttatctgct cgccaggaat
    67381 tttcggaata aatatgcttt tgcataattc gatatataaa gacggtgtag aggaaaagta
    67441 gcgagaaatt ctgcatggtt atgcataacc atgcagaaat gtaaatttaa ttaatgtcta
    67501 attcttttat tttgctctct ttgcgtactg tcagcgtaga ccccattgaa gcggcgatga
    67561 tagcgccgag cgccagtagc tgtatgggtg tcagtgtttc tccgaggaaa atcatcccgg
    67621 aaacggcagc cagcgccggt tccatgctca tcagcgtacc aaatgtccgt gttggcaaac
    67681 gggtgagggc aatcatttcc agcgaataag gcagagcggt cgagagaata gcgacagcca
    67741 gacccaatgg aataaccgac cagtgccaga gtgcttcacc agcctgaagc gctccaattg
    67801 gcacgaaaat taacgctgca atcaacgaac caattgccac cgtcgcaggg ccatgttccg
    67861 ctcctgcgcg ttgcccactt aaaatgtaaa tagcccaaca agccccggcc cccagtgcca
    67921 gcgcacagcc ggttaaatcg acatgggaaa cgtcttgccc cagcggtagc aggaaccaca
    67981 gaccaagaac cgccagcaca acccagacga aatctaccgg gcgacgagaa gagaacagcg
    68041 ccaccgccag tggtccggtg aactccagcg ccaccgcaat acccagcggt actgtctgaa
    68101 tagaaagata aaaaagataa ttcatcccac ccagcgaaac gccgtaaaac aacagcggta
    68161 accgttgctc tttggcaaag cgcagtcgcc atggcttaaa gaacgcgatg aggatcagcg
    68221 ttcctaatgc cagacgcagc gcagtgacac ccggtgcgcc caccagagga aaaagtgact
    68281 tagctaacga ggctccaccc tgaatagacg ccatggcaac gagcaatatg actattggta
    68341 accagaccgg cattttacgt aatgaaccag gcatcctttc tcccacaaat atctagactt
    68401 aagtaaagcg tggagtgtac tggatatacc caatgctggt tgagcatttg ttgaaaaaat
    68461 tttcccccgt tttgactaaa atgcgccagg attgatggaa tcattagtct ggtgattagg
    68521 aataatctgg atgaatgaca gggaaaacat gcgtaatact tacgcagttc tctgaaaaag
    68581 tgatttaaat ttagatggat agcggtgtat ggaaacgttc tgttacatga aatggcccgt
    68641 tagacatcac aaatcgcgaa gagtttccca ttaatttttg atatatttaa aacttaggac
    68701 ttatttgaat cacatttgag gtggttatga aaaaaattgc atgtctttca gcactggccg
    68761 cagttctggc tttcaccgca ggtacttccg tagctgcgac ttctactgta actggcggtt
    68821 acgcacagag cgacgctcag ggccaaatga acaaaatggg cggtttcaac ctgaaatacc
    68881 gctatgaaga agacaacagc ccgctgggtg tgatcggttc tttcacttac accgagaaaa
    68941 gccgtactgc aagctctggt gactacaaca aaaaccagta ctacggcatc actgctggtc
    69001 cggcttaccg cattaacgac tgggcaagca tctacggtgt agtgggtgtg ggttatggta
    69061 aattccagac cactgaatac ccgacctaca aacacgacac cagcgactac ggtttctcct
    69121 acggtgcggg tctgcagttc aacccgatgg aaaacgttgc tctggacttc tcttacgagc
    69181 agagccgtat tcgtagcgtt gacgtaggca cctggattgc cggtgttggt taccgcttct
    69241 aatcactttg gtgatataaa aaatccgcct ctcggggcgg atttttgttt ttaaggtttc
    69301 gggtcgaaaa tatcggttcc gagatggttg taatccacct tctgtaactg gaagttggtg
    69361 atgtatatcg gcccggcttt cttctcagat ataaacgggt atttgatgtt aatttccttc
    69421 gctttaatcc ccgtccactg ggagaaaaag cctaagaagt cattggctga gcggcgggct
    69481 ttaatcacac gatgcgcttt atcgtcgctg gaaatgacca taaaaggcac ctggaaattt
    69541 tgctgatatt tatcatcatg ggcaaggtat tgcacgtctt taccgcgctc tttaaaggcc
    69601 agaccgtggt cagaaaagta aaccagcgag aagctgctgc cgctgttgcg taactgatcg
    69661 tacagcttgc gcagtaaatc gtccgtttgc gtcatggtat agagatagca cgacgtttct
    69721 ttcgattgca caaaggtttc gtattttcct tgtgtcctgt cgcaggcctg cggatgtgag
    69781 cccatcagat gtagaacaat cagctgcggt tgcgagtgct cttgcgccag cacttgagcg
    69841 gtcatatcca gtaacgcttc gtctttggtg tttttatctg cttcaaaatt accttctttc
    69901 aggaagtaca cttcatctgc tcgtttggcg atgctggcga tagcggtatc gtattcgccg
    69961 atttgaccct ggttggaaaa ccaccaggtc tggaagcccg cgcgatttgc cagggtgaca
    70021 aagttatcct gaaactgtgg tttgccatcg acaacgcgat tgagcgttaa gccaagcgat
    70081 ttctgcgtgg agccactggc ggcaatgtag tcagcaaata tcaaaccgtt aacgctgctg
    70141 gcaaacgggg tattgtccca gtgaccgcca aaggcaccga gggcatcgcg acgcgcgctt
    70201 tcaccgatca ccaccacata ggtctgatac ttcggcttaa cggcagtgac cgtccaggta
    70261 tctttcattc cggaaagttt tgccatccgt tcttgctctt caatcacctc gttattattg
    70321 acgatgacat ccttagcaaa acgaaatacc ggatagccag tatctttcag tttaaatacg
    70381 ccaccccagg ccaggttttg cacgggagca acaaaaaatg tcgccacact gaataccaga
    70441 cacaggctgt cgaaggtatt ccagcgcgct ttttcattct ctttttttcg cctgattgct
    70501 attacgccga gcgcaaaaat aaataagccg accaggtagc tgtaccacgg aaaaatcgtc
    70561 aggatttcgg tcgactcttc catattggtg gagtgcaatg ccagcaatgt attgaaatta
    70621 ggcgcgccgt aggcctgagc aaaagggaaa taacaagccg ccaccagcga actgacaccg
    70681 accagaactt tttgtacgcg aggcaatgtt cgccatagca aaagcaaaat agccgtaaac
    70741 gcagcggtgt agagcaaact gaaggggtaa cctaagccga ggttaattaa tagcgactgt
    70801 aaaaagtaga acgcagtcca cgggctaaat acccggctac gggtaacaag cgattctttg
    70861 agggttaaat tcatatgcca ctatcgtaac aaacgccatg tgcttaccct ggcgtcaagg
    70921 gtcaatacct gcaagagtgc gtgaagagtg gaaaggggtc cgcatccgcg agccgcaata
    70981 tacgcagggc tgcaagaaga tagagcgagc cgccgttcag gtcaactact gacgaacaaa
    71041 tcttttgcga aggggattgc aaatccgaca aaaagtgggg tttttcagac caaaacgcgt
    71101 tatgcctgca tgaaagcagg agtgaagcgg cgtaccgcga cgccgctatt tatcggaagg
    71161 tttatcttgc tgcggtttgt tgttgaccat atcgcacaac atagagagca gcattaaccg
    71221 tactttaaag ggagaatgac taaacacgcg catacacctc ttgaactcat tcataagacc
    71281 tcctgacttg ctaatcccgt cgatccttga gggatgattg cattacatac agatatagca
    71341 caggctatat tatatagcta ttgctaaaac gttaattttt tgtaccttcg caactctggt
    71401 ttacaatgtg cgcacgaaat gagaacgcta tgtatgcgtc accataatga ggaagcacaa
    71461 tgagtcgtcg cgcaggtacg ccaacagcaa aaaaagtgac gcagttagtg aacgtggaag
    71521 agcacgttga agggttccgc caggtcagag aggcgcatcg gcgcgagctt attgatgatt
    71581 acgttgagct gatttctgac ttgatcaggg aagtggggga agctcgtcag gtggacatgg
    71641 ctgctcgtct gggagtttcg caaccgacgg tggctaaaat gcttaagcgg ctggcaacca
    71701 tggggctgat tgaaatgatc ccctggcgtg gcgtgttttt aacggcagaa ggagagaagc
    71761 tggcgcagga aagccgcgag cgacatcaga tagtcgaaaa tttcttgttg gtgttgggcg
    71821 tcagtccgga aatcgcccgt cgcgacgcgg aaggcatgga gcaccatgtt agtgaagaga
    71881 cgctcgacgc ttttcgtttg tttacccaga aacacggtgc caaatgagcc tgcctttttt
    71941 acgcacgctg caaggcgatc gtttttttca gttattaatt cttgttggta tcggattaag
    72001 ctttttcgtg ccctttgcac cgaaatcctg gcctgctgct atcgactggc acaccatcat
    72061 caccttaagc ggcctgatgc tgctgaccaa aggtgtggag ttaagcggtt attttgatgt
    72121 gctggggcgc aaaatggtgc gccgctttgc tacggagcgt cggctggcga tgtttatggt
    72181 gctggcggcg gcgctgcttt ctacctttct gaccaacgat gtcgcgctgt ttattgttgt
    72241 tccgctgact atcacgctaa aaagactgtg tgagatcccg gttaatcggc tgattatttt
    72301 tgaggcgctg gcagtcaacg ctggttcgct actgacgcca attggcaacc cgcaaaatat
    72361 tcttatctgg ggacgttctg gtctttcgtt tgccggattt attgcccaaa tggcaccgct
    72421 ggctggcgca atgatgctga cgctcctgct cctgtgctgg tgttgtttcc ctggaaaggc
    72481 gatgcaatac catacggggg tgcaaacacc ggagtggaaa ccgcggctgg tgtggagttg
    72541 tctggggctg tatatcgtct ttctgacggc gctggagttc aaacaagagc tgtggggact
    72601 ggtgattgtg gcggcaggct ttgcgctgct ggcacgtcgc gtggtgctca gtgtggactg
    72661 gacgctgctg ctggtgttta tggcgatgtt tatcgacgtc catttactga cccagcttcc
    72721 agcgttgcaa ggcgtgttgg gtaacgtgag tcatctatct gaacccgggt tatggttaac
    72781 ggcaatcggt ttatcgcagg tgatcagtaa cgtgccgagt accatattgt tgctgaacta
    72841 tgtgccgccg tctttattac tggtatgggc ggtaaacgta ggtggctttg ggttattacc
    72901 cggatcgctg gcaaatttga ttgcgctacg tatggcgaac gatcgccgca tctggtggcg
    72961 tttccatctc tattcaatac cgatgctgtt gtgggcggcg ttggtgggat atgttttgtt
    73021 agttatactc ccggccaact agggtctggc aaataaaaaa ggcggattat gagtccgcct
    73081 tttgctttaa gttttgaaga ttaattcaga cgaaccggca tcccggagcg gtttttaatc
    73141 gcttcatcaa gaacaacctg gtcaacatct ggctgaccgg tcactgtctg cacgctcttc
    73201 gtcagggtaa ttggcacaat ttcctgacct tcaaactggg cttcggtggt agacagcggg
    73261 ttatggactt caatataacg gctgccgtct ggctcggtgg tcgcttttac cggctcatca
    73321 ataaactgta cgcgggtacc gaccggtact ttctcgaaca ggaatttgat gtcttcgtta
    73381 cgcagacgca cacaaccatg acttacacgc aggccgatac cgaagttggc gttggtgcca
    73441 tggatagcat acaggcgacc gatatagagt gcatacagcc ccatcgggtt atccggacct
    73501 gccggaacga cagccggaag cggttcgccc gcagcgcggt actctgcgtg cattttggcg
    73561 gtcggcgtcc aggtcgggcc tgctttttta cgctcaactt tggtggtcca gttgataggc
    73621 gtatctttgc ctaactgacc aatgccgatc ggcagcacga taacggtgtt ggtccctttc
    73681 ggatagtaat aaagacgcat ctcagcactg ttaatgacga tgccttcatg aacggtatcc
    73741 ggcaggatca gctgctgcgg aatgttcagt acagtaccgc ctttcggcag gaaggtatcc
    73801 acacccgggt tcgcttccat catattggaa agccccatct ggtactcggc ggcaaaatac
    73861 tccagcggct gagtgttacc ttcaggaatg gtgatcacct gattctgacc aaccaggcga
    73921 ctcccgtcgg ttggcagagg ataagttacc gcagaggcgg tactgcaaaa gccgacaaca
    73981 gcgaaggccg ctgcgaataa tgttttcaat ttcatattca tgttaagcga gattttgtgc
    74041 ctggcaggcc attgggttga gaatattaga gtattggaag cgcattataa gttcattcca
    74101 gctcacagtg aaatcagatg tgtacgaaat cacatttttt gcctttggct tgagtgtaga
    74161 ccttaagcga ggagcaggat cttctttcag acttatggca taatgcgcgg tttgtcatat
    74221 ctcttttcag gatacgcctg tgttagtttc cagtaacgtc accatgcagt tcggcagtaa
    74281 gccgttgttt gaaaacattt ccgtcaaatt tggcggcggc aaccgttacg gcctgattgg
    74341 cgcgaacggt agtggtaaat ccacctttat gaagatcctc ggcggcgacc ttgagccgac
    74401 gctgggtaac gtttccctcg atcccaacga gcgcattggt aaactgcgtc aggatcagtt
    74461 tgcctttgaa gagttcactg tgctggatac ggtgatcatg gggcataaag agttgtggga
    74521 agtgaagcag gagcgcgacc gcatctatgc tttgccggaa atgagtgaag aagacggcta
    74581 taaagtggcc gatctggaag ttaaatacgg cgaaatggac ggttactctg cggaagctcg
    74641 cgccggtgaa ctgttgcttg gcgtgggaat tccagtggaa cagcactacg gcccgatgag
    74701 tgaagttgct cctggctgga agctgcgtgt gcttctggcg caggcgctgt ttgctgatcc
    74761 ggatattctc ctgctcgacg aaccgaccaa caacctcgac atcgacacca ttcgctggct
    74821 ggaacaggtg ctgaacgagc gtgacagcac catgatcatc atctcgcacg accgtcactt
    74881 ccttaacatg gtctgtaccc acatggcgga tctggattac ggcgagctgc gcgtttatcc
    74941 gggtaactac gatgagtaca tgacggcggc gacccaggcg cgtgaacgtc tgctggccga
    75001 taacgccaag aagaaagcgc agattgctga gttgcaatct ttcgttagcc gctttagcgc
    75061 caacgcctcg aaatctcgcc aggcaacttc gcgcgcgcgc cagattgata aaatcaaact
    75121 ggaagaggtg aaagcctcca gccgtcagaa cccgttcatc cgttttgaac aggataagaa
    75181 actgttccgt aacgcgctgg aagtggaagg tctgaccaaa gggtttgata acggtccgct
    75241 gtttaaaaat ctcaacctgc tgctggaagt gggtgaaaaa ctggcggtac tgggtaccaa
    75301 cggcgtcggt aaatcaacgc tgctgaaaac gctggtgggc gatctgcaac cggacagcgg
    75361 caccgtaaaa tggtctgaga acgcgcgcat tggttactat gctcaggacc acgaatatga
    75421 gtttgaaaat gatctgaccg tgttcgaatg gatgagccag tggaagcagg aaggcgatga
    75481 cgagcaggcg gtacgcagta ttctcggtcg tttgctgttc agccaggacg acatcaaaaa
    75541 gccagctaaa gtgctttccg gtggggaaaa agggcggatg ctgtttggta agttaatgat
    75601 gcagaagccg aacattctga tcatggacga accgaccaac cacctggata tggaatccat
    75661 tgagtcgctg aacatggcac tggaactgta tcagggcacg ctgatctttg tttcacacga
    75721 ccgtgagttc gtaagctccc tggcgacccg cattctggaa atcaccccgg aacgcgtgat
    75781 cgactttagc ggtaattacg aagattacct gcgtagtaaa gggatcgagt aagtgattat
    75841 ccgtcacccc gatactgtcg gggtgacggc ggctgatgac aaatgcaaaa tagcctgatg
    75901 cgctacgctt atcaggccta cgcagtacct gcaatatatt gaatctgcag gactttgtag
    75961 gccggataag gcgttaacgc cgcatcaggc attaacaaag cgcatttgtc agcaatctga
    76021 gtaacgtcga atcgattttc ttaatcccac atcaattcac ttccattaat tctcaaacat
    76081 ccatgcccaa cgctcgctta ccgtgaatgt tgaggtcggc aagcgtaaag cgtccttccc
    76141 agtttgtttc atagtcctcg cgcgggaagt cgcccggcga tgcgcctttt tccagtgcgg
    76201 ccttcacctt gtgcgcgtag gcaagatttt tctcgcacat cggtgccgca ggaatgtaca
    76261 tcacgttgcc ccaaccttgt tgattttcaa cgggggcaac ggaatggatg acgtcgcagt
    76321 gccaccagac ggagtctccg gcttcgagtt ttggaatgct ggttaacgcc tcaatcaaca
    76381 gtggatgcca ttgctctgat accggcaata ctcttccggg cgctacgccg cacagttcat
    76441 cctccggcac atcatcaagc agcggacgta acagtacgta cgccatagct tcaggaatgg
    76501 gcacgacgtg cagcagcccc tgaccaggca gcatatcaga gagcgctgtc cagccctgga
    76561 atgtccgaaa cacggaacat ttggtggtgt tgtccaccgt gtactcttca acttccgtac
    76621 gatgtgccgc atgccaggga tcatattgcg ccagattgcc attaaagacg ttggcgaaaa
    76681 cgcgctgata cgctggaagc agccagcgtt ccagtgcccc ggagtcggta tgcgctccaa
    76741 gacctttgga ggtcgttccg ggcggacggc ggcggatacg gtcagggtag atgacgctca
    76801 catccgggtt aaaccattgc tttccatcac tttcaaatgt ccacagacga ttgagaaacg
    76861 actgcgcatt cgccatttct tcactctggc gggcctgcat ttgcgcctgc gaccagtaga
    76921 tggggtaaat ctcgggacgt gaagcgctga gcgtcccgaa gaaattatcg ccggggcctt
    76981 tgtagacctc gtcaaagcgg ttgcggtcca gatagtccag catcgactga tcccagccta
    77041 gcgcttgttc gcgggggaaa tggcctttta tcaccgcaca accgcgacgt ttaatctgtt
    77101 cgcgctgctc tgcagtaaca tgacctgctt tgatatcggc ataagacagc accggccaga
    77161 cggcatcgcc ctgtgctttg agtgcgttga tttcagccac tcgcgtggca atgtcatcgc
    77221 ttagctgatt aaagatctgc tggacgtcgc caagctgcgc ccgcagcgcg tgcttcatct
    77281 gacggatagc tgctttgtga tcggcaggca atgtgtcgct ggtaaaagta gaagccataa
    77341 ccacctctca ttaactttca ttcgaaacca ttctgatttg catgtgacaa tataagttat
    77401 aaataagtta atgcaagttt aatgatttga tgtgatgtac aggatgtaaa aagaagggaa
    77461 aaccggagcg cacggctccg gtagagaggt cagctgttaa aaggggatgt gttatccagc
    77521 accgcctgaa tcacattcag cgcgccttca tgattattat catcggtagc gtaacgggcg
    77581 atttgtttaa tgttttccgc agcattgccc atcgcaaagg aataacgcgc cattttcagc
    77641 atctccgcat cgttaccgct gtcgccaatc gctaccacat tttgcggtga cagatcccag
    77701 cgtttcagta accgcgaaat accgtttgct ttatgtagac cgggaataat caggtcgata
    77761 aagccaaaac cactggtaac gggtttcata atgccatcga gcgctacgtg cagtttgtcg
    77821 atcactaacg ggatttgttc atccggcagg ttgagcgaaa acttgaacag tacgtcgtca
    77881 atctcctgat aatcttttac aggtttcagg cgatggtagt gttttgccat cagtgcgaca
    77941 aatgcttcgg gggcattttc gctgacatat gcactttgca gaccgcaggc gacaaaattg
    78001 agttgcttat cttttagcaa ctcgccaata acaatccgcg attcatgtcg ggtcagttcg
    78061 ccgtggaaca actgcttgcc atgttcgtaa accagtgcgc cgttttccgc gacaaaagag
    78121 atctcatcct ttagctcagg aaagaatgaa ataagctggt aatactgatt accgctggca
    78181 acaacgaact taatgccgcg ctttttcagt tcctgatatt gcgccataaa acgtggttgg
    78241 ttgtacgttt tggcgtcgtt aagaaaagta ccgtccatgt ctgtgacgat aacttttacg
    78301 ctcataggtg tgctcctggc tcgaaaatga aaccgtaaca gtgtaataac aatgtgacgc
    78361 agagcacaaa ttatatttcg aatgaaagta aggatgaaat tgatgatgtg aatgatttag
    78421 cccggcgacg acgccgccgg gccgaggaga ttacagcata tgttcagtac gggcgatgat
    78481 atcgtcctga gcgtctggag agagcgcggt gaagaacgcg gaatagcccg cgacacgcac
    78541 taccagatcg cgatactgat cgggatgttt tttcgcatcc agcagcgttt cgcgggaaac
    78601 gatgttgtac tgaatatgcc agcctttatg cacttcaaag aaggtacgca gcaggatcat
    78661 cagtttctgc ttgtcagatt cgttctccag cgttgccgga ttcagtttct ggttgagcaa
    78721 cacgccgccg agaatcgctg ccgtaggcag tttacccact gagccaatga ccgcagtagg
    78781 gccaagatgg tcagtaccgg aggccgggct tgcgccttct gccagcgggg tgtgggcttt
    78841 acgcccgtcc ggtgttgcca tagtctgcgc gccaaacggt acgttagcgg agattgatga
    78901 cgtacccgcg taatagttgc cgccaaccgg accacgaccg tagcgcggat tatggtactg
    78961 tttcagttcg tcgatatagg tctgataagc gcgagccagc agcgtatcga cagtatcatc
    79021 gtcgttgccg tacttcggcg caccgttaat cagccgctga cgcagctgct cgtgagtcag
    79081 gccgtcgaag tcatctgcca gtgcggcagc aagctgttgc tgaccaatcg caccttgttc
    79141 aaacaccagt ttcttcactg ccgccaggct gttgccgagg ttggcaatgc cgacctgcag
    79201 gccagaaacc cagtcatatt tcgcgccgcc ttgcttgata cttttcgctc gctcaataca
    79261 gtcatccacc agcgccgagc agagaatatc gtgcacgttc tcttccagca tggtgtcgac
    79321 gacatattcg atttcgattg atttgcgggt gtagtaacgg atttgcgtat cccacgcgtc
    79381 catcacttca tcgaagttgt tgaagttacc tgccgacaac gctttttctt gtggcaggaa
    79441 cactttgccg ctggtggcat catgcccgcc ttccagcgcc gccagcatca cgcgggcgaa
    79501 gttgataaag ctcatgccgg tacagcgata gccccatttg ccaccgacgg cggtttctat
    79561 acaaccaatc gctgcgtagt cataagcgtc ctgcggttca ataccgagtt taataaattc
    79621 cgggatcacg atttcgtcgt tgttgaacgc cggcatcccg aagccgcaac ggatcacctg
    79681 tacgcaggcg tcgaggaaat cgttgctcat tcctgcatgg taacgcacgc tgaggttagg
    79741 ctgagtggaa cgcaggcgac cgcaggattc gaggatcgcg taagagagtg gattcaccgc
    79801 gtccattggt tgaccatcaa ccagattttg cccgccaata gtgacgttct gatacagcgg
    79861 acttcccgca gaggcttttg agtgtgagcc ggagcggatc ttgttcactt ccagcagttt
    79921 cagccagcag ctatgcagca tctcgatggc gtgttcgcga tccagcgtct ggttgagttc
    79981 aacgtcgcgg cgatagtacg ggtagagata ctggtccata cgaccaaacg atactgagtg
    80041 accgttagat tcgatctgca aaatcaactg gatgaagtaa cacagttgca gcgcctgcca
    80101 gaaagtctgc ggcggctggt gggcgataag atcgcagttt tctgccatcg ccagcagttc
    80161 atcgcgacgg ctttcgcggg tttcggtcgc ggccatttca cgcgccaggg cagcgaaacg
    80221 ttcaatgtgt tcactgactg ccaccagcac gatatcaatc gctttcagga attgctcacc
    80281 gtgtaaatct tccagcaccg tcaggttgat gcgcgagcga cgttccgcta ctttctcgcg
    80341 cagaccatca agcccttttt ccagcagcag cgggaaattc accgccaggt gcgcatcgcc
    80401 ggaggtcata ttgccttccg ctttaatgat tccggtcgcc agcagacctt tttgctcatc
    80461 ggtaaacatg ccgtagcagc gatcctgtac ggtctgaccg cgccaccacg ggcacacttc
    80521 atgcagaacg cgtttgttct cttcgctcac cgcaaagcca gcaccgggac gatctgccag
    80581 atcatcaatc tctttttcga tccacgagac agtatattcc gggaagatcg gcgcggcgcg
    80641 aacttcgctt gcctggttgc caatgatcaa ctcatcgtgt ttgatccaga tggtgcgatt
    80701 cgccaggtga tgcgccagtg ccagcgcgcg acgtaccggg atcggcttat cgagatgttg
    80761 ttgatacatc tcggtatagt gctgcgcgcg ctcggtacag actggcggtt tcacaatatg
    80821 caccagcgca tttttgtgcg ctttaatgcg gtcgctgagc gtgtccagtt tcagtgtggt
    80881 catggttgtt atcctcgtaa ggtcgcggtt aaccctttct ggcaggcata ctgctgggca
    80941 aagtcgagca gttctggcgc atcaagcggt ttttccgggg cgtcataggg cagattaagt
    81001 aagtgatatt tgttgatgcc cagcgtgtgg tagggcagaa aatgaatttc gccaacgtgc
    81061 agctcgtcgg cggcaaaatc ggtaatggct tttacagagg tttcgtcggc attaaagccc
    81121 tgaatcagcg gcacgcggat aatgattttt ttgcccgctg cggcgagttt tttcaggtta
    81181 tccagcactc tggcggcgtt accgtcggtc cactgtttaa acggcgcgtc ggcaacgtgt
    81241 tttaaatcgg caagaaacag atcgatatag ggcagagaag gggcgatata tttccacggc
    81301 acatgcagac aggtttctac cgcagtatga atgcctgcct cgtggctggc ttgcagtagc
    81361 gccatcgcca tttccggctg cataaagggc tcaccacccg aaagcgttaa accgccgccg
    81421 ctgcgatcgt aaaacggttt atcgcgcaga acggtcgtca tgatctcctc aacgcttttc
    81481 acttcaccac acacggttaa tgcctgtgtc ggacagcagt cggttaacgc cgtcagatgc
    81541 tccggggtta acttttcccg atgaataagc aaaccattca gcgcgcgctc aatcacttcc
    81601 ggcgcggcct tagcgcacag ctcgcagcct tccagacaca gtcgtgcgtc atacagcaga
    81661 tcctgcgtgc gggcgcggct ttccgggttc tgacaccagc ggcagcccag cgaacagcct
    81721 ttaagaaata cgaccgtgcg gataccgggg ccatcatggg tcgagtagcg ctgaatattg
    81781 aaaatcatag ttgcctctct atttcgttca agcattaaaa tactttcgaa tgaaagttag
    81841 attgatgtgc gtcaactgtt cagagagttt tcccgtgata gtctacattc agacaaaaag
    81901 tacattttga ggatggttat ggaactgtat ctggatactt cagacgttgt tgcggtgaag
    81961 gcgctgtcac gtatttttcc gctggcgggt gtgaccacta acccaagcat tatcgccgcg
    82021 ggtaaaaaac cgctggatgt tgtgcttccg caacttcatg aagcgatggg cggtcagggg
    82081 cgtctgtttg cccaggtaat ggctaccact gccgaaggga tggttaatga cgcgcttaag
    82141 ctgcgttcta ttattgcgga tatcgtggtg aaagttccgg tgaccgccga ggggctggca
    82201 gctattaaga tgttaaaagc ggaagggatt ccgacgctgg gaaccgcggt atatggcgca
    82261 gcacaagggc tgctgtcggc gctggcaggt gcggaatatg ttgcgcctta cgttaatcgt
    82321 attgatgctc agggcggtag cggcattcag actgtgaccg acttacacca gttattgaaa
    82381 atgcatgcgc cgcaggcgaa agtgctggca gcgagtttca aaaccccgcg tcaggcgctg
    82441 gactgcttac tggcaggatg tgaatcaatt actctgccac tggatgtggc acaacagatg
    82501 attagctatc cggcggttga tgccgctgtg gcgaagtttg agcaggactg gcagggagcg
    82561 tttggcagaa cgtcgattta accggacgtt ctgcatcctc ataaattgct gatgacgtgg
    82621 cggagtgccg cgtcttatca ggcctggagg tggcaattac tgcccacaca cctcacaccc
    82681 cggattacgc atcagtttca tttcgcgaaa ctgacaggtc atcgcatcgt acatgacgat
    82741 tttcccgctg gccggtttgc cataacctgc cagcattttg atcgcttcca ttgcctgcaa
    82801 cgaaccaatt acgccgatca acggtgccat tacgcctgct tccacgcagg ttaatgcatt
    82861 ttcaccaaac aaacggctaa ggcagcgata gcacggttca ccgtcctgat aagtaaagac
    82921 ggtgatttga ccttccatac gaattgccgc gccggaaacc agcggtacct tcgcggcaaa
    82981 acagcctgcg ttcagttgat tacgtaccgc aacgttatcc gtacagtcga gcaccagatc
    83041 gtgttcagca atcaatgctg caagttctgc gtcatccagc agtgcattga ctggcgtaat
    83101 cgcgatatgt gggttgatcc gcgtcagggc gtcacgggcg gattccacct tcggttgccc
    83161 gaccgtggca tcactgtgca gtgtctggcg ttgcagattc gagagcgaaa ccgtgtcgaa
    83221 gtcgagcagc gtcaggttac cgacaccggc gcttgccaga tactgcgagg ctgcacagcc
    83281 gaggccgccc aggcccacta tcagcacgcg agaatctttc agcgcctcct ggccgtcaaa
    83341 atcaaagccg cgcagaatga tttgccggtt gtagcgcagc atctcctgat cgctgagttc
    83401 cgccattaca ggcctccgaa caacgcgtta aacggttcta cttccaccca ttcgcccact
    83461 tccacattgc cgcgatcgcg ttccagcacg ataaagcagt tgccgaggct aaaggagcta
    83521 aatatatgtg aaccctgatg tccggtggtc gtcacttcca gttcgccatc ggcgttgcgt
    83581 tgcagcacgc cgcgctggaa atcaagacgt cctggcgttt ttttcaggcg ggacgctgtg
    83641 cgtacgcgct ggcgcgcggg caggccgctg gcggtgttac cgcttagttt tgccagcaaa
    83701 ggctgtacca gttgatagaa ggtcagcgtc gctgaaaccg ggttgcccgg caggccgcag
    83761 aaccagctat tgctgagttt accgaacgcg aacggtttac ctggtttaat cgccagcttc
    83821 cagaaggcga tctcccccag ctcttcaaga atcgttttgg tgtaatccgc ctcacccact
    83881 gaaacaccgc cggaactgat caccacatcc gcctggctgt cggcttcaat aaatgcggcg
    83941 cgcagggcat ggggatcgtc gcggataatc cctaagttaa ttacctcgca tcccaactgt
    84001 tctaacatca ggtgtacggc gagacggttg gtatcgtaga tttggccgtc gcccagcggc
    84061 tgaccgggca actggagttc atcaccggta gaaaaaagcg ctacacgcac tttacgaatc
    84121 accggaactt cggcaatccc cagtgaagca attactggca gctctgcggt agtcaggcga
    84181 gttcccgccg ggaaaacaac cgcacctgca gagatatctt caccgcgacg gcgaatattt
    84241 tgcccgctac gcacttcagc agtaaaacgc acgccattgt ccatttgttc agtctgctcc
    84301 tgcatcacca ccgcttcgca gccttccggc accggcgcac cggtcataat acgaatgcag
    84361 gtacccgcag gccattcacc atggtatggc tgaccggcaa aggatttacc ggcaacgggc
    84421 agcggttgcc cggaggcaat atcggctaaa cgcaccgcgt agccgtccat tgcggagtta
    84481 tcaaaccccg gaacatcaag cggcgaaacg acatcgctcg ccagaatacg accaaaacac
    84541 tgtaccagtg gcagcgtttc ctgggcggtc agtggggtga cgcgagaaag catctcatta
    84601 agcgcggtgt cgagcgacat caatccggtg gtaaattcca tgaaaacact cctgcggagg
    84661 caaaatcgaa tttgcctatt atgtcagaaa aacgccacag actgtatgcc acctcgggcg
    84721 tagcgctggg tcctgccttt acatgccata tccatctttc tatattcaaa aattgaatga
    84781 gtaattcata aaaattctga tatttatagc aaaagtggcg aaccaccctt aatggacgaa
    84841 tactatgggc aaagcagtca ttgcaattca tggtggcgca ggtgcaatta gccgcgcgca
    84901 gatgagtctg caacaggaat tacgctacat cgaggcgttg tctgccattg ttgaaaccgg
    84961 gcagaaaatg ctggaagcgg gcgaaagtgc gctggatgtg gtgacggaag cggtgcgtct
    85021 gctggaagag tgtccactgt ttaacgccgg aattggcgct gtctttacgc gtgatgaaac
    85081 ccatgaactg gacgcctgtg tgatggatgg taacaccctg aaagccggtg cggtggcggg
    85141 cgttagtcat ctgcgtaatc cggttcttgc cgcccggctg gtgatggagc aaagcccgca
    85201 tgtgatgatg attggcgaag gggcagaaaa ttttgcgttt gctcgtggca tggagcgcgt
    85261 ctcgccggag attttctcca cgcctttgcg ttatgaacaa ctactggcag cgcgcaagga
    85321 aggggcaacc gtcctcgacc atagcggtgc gccactggat gaaaaacaga aaatgggcac
    85381 cgtgggggcc gtggcgttgg atttagacgg caatttggcg gcagccacgt ccacaggcgg
    85441 aatgaccaat aaattacccg gacgagttgg cgatagtccc ttagtgggtg ccggatgcta
    85501 cgccaataac gccagtgtgg cggtttcttg taccggcacg ggcgaagtct tcatccgcgc
    85561 gctggcggca tatgacatcg ccgcgttaat ggattacggc ggattaagtc tcgcggaagc
    85621 ctgcgagcgg gtagtaatgg aaaaactccc tgcgcttggc ggtagcggtg gcttaatcgc
    85681 tatcgaccat gaagggaatg tcgcgctacc gtttaacacc gaaggaatgt atcgcgcctg
    85741 gggctacgca ggcgatacgc caaccaccgg tatctaccgt gaaaaagggg acaccgttgc
    85801 cacacagtga tgaacttgat gccggtaatg tgctggcggt tgaaaatctg aatattgcct
    85861 ttatgcagga ccagcagaaa atagctgcgg tccgcaatct ctcttttagt ctgcaacgcg
    85921 gtgagacgct ggcaattgtt ggcgaatccg gctccggtaa gtcagtgact gcgttggcat
    85981 tgatgcgcct gttggaacag gcgggcggtt tagtacagtg cgataaaatg ctgttgcagc
    86041 ggcgcagtcg cgaagtgatt gaacttagcg agcagaacgc tgcacaaatg cgccatgttc
    86101 gcggtgcgga tatggcgatg atatttcagg agccgatgac atcgctgaac ccggtattta
    86161 ctgtgggtga acagattgcc gaatcaattc gtctgcatca gaacgccagt cgtgaagaag
    86221 cgatggtcga ggcgaagcgg atgctggatc aggtacgcat tcctgaggca caaaccattc
    86281 tttcacgtta tccgcatcaa ctctctggcg ggatgcgcca gcgagtgatg attgcgatgg
    86341 cgctgtcatg ccgcccggcg gtgctgattg ccgatgagcc aaccaccgcg ctggatgtca
    86401 ctattcaggc gcagatcctg caattaatca aagtattgca aaaagagatg tcgatgggcg
    86461 ttatctttat cactcacgat atgggcgtgg tggcagagat tgccgatcgg gtactggtga
    86521 tgtatcaggg cgaggcggtg gaaacgggta ccgtcgaaca gatttttcat gcaccgcaac
    86581 atccttacac ccgtgcgctg ttagctgctg ttccgcaact tggtgcgatg aaagggttag
    86641 attatccccg acgtttcccg ttgatatcgc ttgaacatc
//
LOCUS       DACAOP010000007        80660 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.007, whole genome shotgun sequence.
ACCESSION   DACAOP010000007 DACAOP010000000
VERSION     DACAOP010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 80660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80660
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.007"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..1152)
                     /locus_tag="IT892_000527"
     CDS             complement(<1..1152)
                     /locus_tag="IT892_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAP3133770.1"
                     /translation="MAMSDEAMFAPPQGITIEAVNGMLAERLAQKHGKASLLRAFIPL
                     PPPFSPVQLIELHVLKSNFYYRYHDDGSDVTATTEYQSEMVDYSRHAVLLGSSGMAEL
                     RFIRTHGSRFTPQDCTLFNWLARIITPVLQSWLNDEEQQVALRLLEKDRDHHRVLVDI
                     TNAVLSHLDLDDLIADVAREIHHFFGLASVSMVLGDHRKNEKFSLWCSDLSASHCACL
                     PRCMPGESVLLTQTLQTRQPTLTHRADDLFLWQRDPLLHLLASNGCESALLIPLTFGN
                     HTPGALLLAHTSSTLFSEENCQLLQHIADRIAIAVGNADAWRSMTDLQESLQQENHQL
                     SEQLLSNLGVGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVI"
     gene            complement(1182..1595)
                     /gene="hyfJ"
                     /locus_tag="IT892_000528"
     CDS             complement(1182..1595)
                     /gene="hyfJ"
                     /locus_tag="IT892_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416985.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 assembly chaperone HyfJ"
                     /protein_id="HAP3133771.1"
                     /translation="MAEECREIVFWTLRKKFVASSDEMPEHSSQVMYYSLAIGHHVGV
                     IDCLSVAFRCPLTEYEDWLALVEEEQARRKMLGVMTFGEIVIDASHTALLTRAFAPLA
                     DDAMSAWQARSIQFIHLLDEIVQEPAIYLMARKIA"
     gene            complement(1588..2346)
                     /gene="hyfI"
                     /locus_tag="IT892_000529"
     CDS             complement(1588..2346)
                     /gene="hyfI"
                     /locus_tag="IT892_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfI"
                     /protein_id="HAP3133772.1"
                     /translation="MSPVLTQHVSQPITLDEQTQKIKQHLLQDIRRSAYVYRVDCGGC
                     NACEIEIFAAITPVFDAERFGIKVVSSPRHADILLFTGAVTRAMRMPALRAYESAPDH
                     KICVSYSACGVGGGIFHDLYSVWGGSDTIVPIDVWIPGCPPTPAATIHGFAVALGLLQ
                     QKIHAVDYRDPTGVTMQPLWPQIPPSQRIAVEREARRLAGYRQGREICDRLLRHLSDD
                     PTGNRVNTWLREADDPRLNSIVQQLFRILRGLHG"
     gene            complement(2343..2888)
                     /gene="hyfH"
                     /locus_tag="IT892_000530"
     CDS             complement(2343..2888)
                     /gene="hyfH"
                     /locus_tag="IT892_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit H"
                     /protein_id="HAP3133773.1"
                     /translation="MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACG
                     ACACACPANALTIQTDDQQNTRTWQLYLGRCIYCGRCEEVCPTRAIQLTNNFELTVTN
                     KADLYTRATFHLQRCSRCERPFAPQKTVALAAELLAQQQNAPQNREMLWAQASVCPEC
                     KQRATLINDDTDEPLVAKEQL"
     gene            complement(2898..4613)
                     /gene="hyfG"
                     /locus_tag="IT892_000531"
     CDS             complement(2898..4613)
                     /gene="hyfG"
                     /locus_tag="IT892_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfG"
                     /protein_id="HAP3133774.1"
                     /translation="MNVNSSSNRGEAILAALKTQFPGAVLDEERQTPEQVTITVKINL
                     LPDVVHYLYYQHDGWLPVLFGNDERTLNGHYAVYYALSMEGAEKCWIVVKALVDADSR
                     EFPSVTPRVPAAVWGEREIRDMYGLIPVGLPDQRRLVLPDDWPEDMHPLRKDAMDYRL
                     RPEPTTDTETYPFINEGNSDARVIPVGPLHITSDEPGHFRLFVDGEQIVDADYRLFYV
                     HRGMEKLAETRMGYNEVTFLSDRVCGICGFAHSVAYTNSVENALGIEVPQRAHTIRSI
                     LLEVERLHSHLLNLGLSCHFVGFDTGFMQFFRVREKSMTMAELLTGSRKTYGLNLIGG
                     VRRDILKEQRLQTLKLVREMRADVSELVEMLLATPNMEQRTQGIGILDRQIARDYSPV
                     GPLIRGSGFARDLRFDHPYADYGNIPKTLFTFTGGDVFSRVMVRVKETFDSLAMLEFA
                     LDNMPDTPLLTEGFSYKPHAFALGFVEAPRGEDVHWSMLGDNQKLFRWRCRAATYANW
                     PVLRYMLRGNTVSDAPLIIGSLDPCYSCTDRVTLVDVRKRQSKTVPYKEIERYGIDRN
                     RSPLK"
     gene            complement(4603..6183)
                     /gene="hyfF"
                     /locus_tag="IT892_000532"
     CDS             complement(4603..6183)
                     /gene="hyfF"
                     /locus_tag="IT892_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit F"
                     /protein_id="HAP3133775.1"
                     /translation="MSYSVMFALLLLTPLLFSLLCFACRKRGHSATLAVTVLHSLGIT
                     LLLILALWVVQTAADAGEIFAAGLWLHIDGLGGLFLAILGVIGFLTGVYSIGYMRHEV
                     AHGELSPVTLCDYYGFFHLFLFTMLLVVTSNNLIVMWAAIEATTLSSAFLVGIYGQRS
                     SLEAAWKYIIICTVGVAFGLFGTVLVYANAASVMPQAEMAIFWSEVLKQSSLLDPTLM
                     LLAFVFVLIGFGTKTGLFPMHAWLPDAHSEAPSPVSALLSAVLLNCALLVLIRYYIII
                     CQAIGSDFPNRLLLIFGMLSVAVAAFFILVQRDIKRLLAYSSVENMGLVAVALGIGGP
                     LGIFAALLHTLNHSLAKTLLFCGSGNVLLKYGTRDLNVVCGMLKIMPFTAVLFGGGAL
                     ALAGMPPFNIFLSEFMTVTAGLARNHLLLIVLLLLLLTLVLAGLVRMAARVLMAKPPQ
                     AVNRGELGWLTTSPMVILLVMMLAMGTHIPQPVIRILAGASTIVLSGTHDLPAQRSTW
                     HDFLPSGTASVSEKHSER"
     gene            complement(6188..6838)
                     /gene="hyfE"
                     /locus_tag="IT892_000533"
     CDS             complement(6188..6838)
                     /gene="hyfE"
                     /locus_tag="IT892_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 membrane subunit"
                     /protein_id="HAP3133776.1"
                     /translation="MTGSMIVNNLAGLMMLTSLFVISVKSYRLSCGFYACQSLVLVSI
                     FATLSCLFAAEQLLIWSASAFITKVLLVPLIMTYAARNIPQNIPEKALFGPAMMTLLA
                     ALIVLLCAFVVQPVKLPMATGLKPALAVALGHFLLGLLCIVSQRNILRQIFGYCLMEN
                     GSHLVLALLAWRAPELVEIGIATDAIFAVIVMVLLARKIWRTHGTLDVNNLTALKG"
     gene            complement(6850..8289)
                     /locus_tag="IT892_000534"
     CDS             complement(6850..8289)
                     /locus_tag="IT892_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit D"
                     /protein_id="HAP3133777.1"
                     /translation="MENLALTTLLLPFIGALVVSFSPQRRAAEWGVLFAALTTLCMLS
                     LISAFYQADKVAVTLTLVNVGDVALFGLVIDRVSTLILFVVVFLGLLVTIYSTGYLTD
                     KNREHPHNGTNRYYAFLLLFIGAMAGLVLSSTLLGQLLFFEITGGCSWALISYYQSDK
                     AQRSALKALLITHIGSLGLYLAAATLFLQTGTFALSAMSELHGDARYLVYGGILFAAW
                     GKSAQLPMQAWLPDAMEAPTPISAYLHAASMVKVGVYIFARAIIDGGNIPHVIGGVGM
                     VMALVTILYGFLMYLPQQDMKRLLAWSTITQLGWMFFGLSLSIFGSRLALEGSIAYIV
                     NHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLHTLPLPGVGFCVAALAITGVPPFNGF
                     FSKFPLFAAGFALSVEYWILLPAMILLMIESVASFAWFIRWFGRVVPGKPSEAVADAA
                     PLPGSMRLVLIVLIVMSLISSVIAATWLQ"
     gene            complement(8306..9253)
                     /gene="hyfC"
                     /locus_tag="IT892_000535"
     CDS             complement(8306..9253)
                     /gene="hyfC"
                     /locus_tag="IT892_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfC"
                     /protein_id="HAP3133778.1"
                     /translation="MRQTLCDGYLIIFALAQAVILLALTPLFTGISRQIRARMHSRRG
                     PGIWQDYRDIHKLFKRQEVAPTSSGLMFRMMPWVLISSMLVLAMALPLFITVSPFAGG
                     GDLITLIYLLALFRFFFALSGLDTGSPFAGVGASRELTLGILVEPMLILSLLVLALIA
                     DSTHIEMISKTLATGWNSPLTTVLALLACGFACFIEMGKIPFDVAEAEQELQEGPLTE
                     YSGAGLALAKLGLGLKQIVMAALFVALFLPFGRAQELSLACLLTSLVVTLLKVLLIFV
                     LASIAENTLARGRFLLTHHVTWLGFSLAALAWVFWLTGL"
     gene            complement(9264..11282)
                     /gene="hyfB"
                     /locus_tag="IT892_000536"
     CDS             complement(9264..11282)
                     /gene="hyfB"
                     /locus_tag="IT892_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit B"
                     /protein_id="HAP3133779.1"
                     /translation="MDALQLLTWSLILYLFASLASLFLLGLDRLAIKLSGITSLVGGV
                     IGIISGITQLHAGVTLVARFATPFNFADLTLRMDSLSAFMVLVISLLVVVCSLYSLTY
                     MREYEGKGAAAMGFFMNLFIASMVALLVMDNAFWFIVLFEMMSLSSWFLVIARQDKTS
                     INAGMLYFFIAHAGSVLIMIAFLLMGRESGSLDFASFRTLSLSPGLASAVFLMAFFGF
                     GAKAGMMPLHSWLPRAHPAAPSHASALMSGVMVKIGIFGILKVAMDLLAQTGLPLWWG
                     ILVMAIGAISALLGVLYALAEQDIKRLLAWSTVENVGIILLAVGVAMVGLSLHDPLLT
                     VVGLLGALFHLLNHALFKGLLFLGAGAIISRLHTHDMEKMGALAKRMPWTAAACLIGC
                     LAISAIPPLNGFISEWYTWQSLFSLSRVEAVALQLAGPIAMVMLAVTGGLAVMCFVKM
                     YGITFCGAPRSTHAEEAQEVPNTMIVAMLLLAALCVFIALSASWLAPKIMHIAHAFTN
                     TPPVTVASGIALVPGTFHTRVTPSLLLLLLLAMPLLPGLYWLWCRSRRAAFRRTGDAW
                     ACGYGWENAMAPSGNGVMQPLRVVFCALFRLRQQLDPTLRLNKGLAHVTARAQSTEPF
                     WDERVIRPIVSATQRLAKEIQHLQSGDFRLYCLYVVAALVVLLIAIAV"
     gene            complement(11282..11899)
                     /gene="hyfA"
                     /locus_tag="IT892_000537"
     CDS             complement(11282..11899)
                     /gene="hyfA"
                     /locus_tag="IT892_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311370.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfA"
                     /protein_id="HAP3133780.1"
                     /translation="MNRFVVAEPLWCTGCNTCLAACSDVHKTQGLQQHPRLALAKTST
                     LTAPVVCHHCEEAPCLQVCPVNAISQRDDAIQLNESLCIGCKLCAVVCPFGAISASGS
                     RPVNAPAQYVFQADGSLKDGEENAPTQHALLRWEPGVQTVAVKCDLCDFLPEGPACVR
                     ACPNQALRLITDDSLQRQMKEKQRLAASWFANGGEDPLSLTQEQR"
     gene            complement(12152..12622)
                     /gene="bcp"
                     /locus_tag="IT892_000538"
     CDS             complement(12152..12622)
                     /gene="bcp"
                     /locus_tag="IT892_000538"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HAP3133781.1"
                     /translation="MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTP
                     GCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDEDHQVCEQ
                     FGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA"
     gene            complement(12622..13194)
                     /locus_tag="IT892_000539"
     CDS             complement(12622..13194)
                     /locus_tag="IT892_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     repressor"
                     /protein_id="HAP3133782.1"
                     /translation="MTLSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAML
                     GEEFTFIMLLSGSWNAITLIESTLPLKGAELDLLIVMKRTTARPRPPMPASVWVQVDV
                     ADSPHLIERFTALFDAHHMNIAELVSRTQPAENERAAQLHIQITAHSPASADAANIEQ
                     AFKALCTELNAQGSINVVNYSQHDEQDGVK"
     gene            13340..14218
                     /gene="dapA"
                     /locus_tag="IT892_000540"
     CDS             13340..14218
                     /gene="dapA"
                     /locus_tag="IT892_000540"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAP3133783.1"
                     /translation="MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGT
                     TGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLT
                     VTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGI
                     KEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAAHDMAQMC
                     KLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITD
                     SGRETVRAALKHAGLL"
     gene            14235..15269
                     /gene="bamC"
                     /locus_tag="IT892_000541"
     CDS             14235..15269
                     /gene="bamC"
                     /locus_tag="IT892_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708316.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HAP3133784.1"
                     /translation="MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEA
                     APLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGD
                     TASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGR
                     YQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAAN
                     AAQNRASTTMDVQSAADDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNM
                     AVTYKPLSDSDWQELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDAL
                     VAVFQAAFSK"
     gene            15482..16195
                     /gene="purC"
                     /locus_tag="IT892_000542"
     CDS             15482..16195
                     /gene="purC"
                     /locus_tag="IT892_000542"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAP3133785.1"
                     /translation="MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFD
                     RKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLV
                     KRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKAND
                     VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSL
                     GGLIEAYEAVARRLGVQLD"
     gene            16363..17226
                     /locus_tag="IT892_000543"
     CDS             16363..17226
                     /locus_tag="IT892_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HAP3133786.1"
                     /translation="MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLIVV
                     LVAGYYGVDLTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMG
                     KTYQQPKLVMYRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFA
                     QGYVIAHEVGHHVQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWGHSMQ
                     QQGVLETGDLEEALNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGD
                     PAQCNTFGKSI"
     gene            17241..19256
                     /locus_tag="IT892_000544"
     CDS             17241..19256
                     /locus_tag="IT892_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(Met) cytidine acetyltransferase"
                     /protein_id="HAP3133787.1"
                     /translation="MAELTALHTLTAQMKREGIRRLLVLSGEEGWCFDHALKLRDALP
                     GDWLWISPQPVAENHCFPSALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWL
                     VLLLPVWEEWENQPDADSLRWSDCPDPIATPHFVQHLKRVLTANNDAILWRQNQPFTL
                     VHFAPRTDWHPATGTPQPEQQQLLQQLLTMPPGVAAVTAARGRGKSALAGQLISRIAG
                     SAIVTAPAKAATDVLAQFAGEKFRFIAPDALLASDEQADWLVVDEAAAIPAPLLHQLV
                     SRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRWAQGCPLEKMVSEAL
                     VFDDENFTHEPQGDIVISAFEQTLWRSEPETPLKVYQLLSGAHYRTSPLDLRRMMDAP
                     GQHFLQAAGENEIAGALWLVDEGGLSQELSQAVWAGFRRPRGNLVAQSLAAHGSNPLA
                     ATLRGRRVSRIAVHPARQREGTGRQLIAGALQYTQDLDYLSVSFGYTGELWRFWQRCG
                     FVLVRMGNHREASSGCYTAMALLPMSDAGKQLAEGEHYRLRRDAQALAKWNGETLPVD
                     PLNDAVLSDDDWLELAGFAFAHRPLLTSLGCLLRLLQTSELALPALRGRLQKNVSDAQ
                     LCTTLKLSGRKLLLVRQREEAAQALYALDDVRTERLRDRITQWQFFH"
     gene            19330..20028
                     /gene="ypfH"
                     /locus_tag="IT892_000545"
     CDS             19330..20028
                     /gene="ypfH"
                     /locus_tag="IT892_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311362.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAP3133788.1"
                     /translation="MKHDHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIGSWFAPLFP
                     DALVVSVGGAEPSGNPAGRQWFSVQGITEDNRQERVDAIMSTFIETVRYWQKQSGVGA
                     NATALIGFSQGAIMALESIKAEPGLASRVIAFNGRYASLPETASTATTIHLIHGGEDP
                     VIDLAHAVAAQEALISAGGDVTLDIVEDLGHAIDNRSMQFALDHLRYTIPKHYFDEAL
                     SGGKPGDDDVIEMM"
     gene            complement(20109..20309)
                     /locus_tag="IT892_000546"
     CDS             complement(20109..20309)
                     /locus_tag="IT892_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpfN family protein"
                     /protein_id="HAP3133789.1"
                     /translation="MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPP
                     HRDFNDKWDDDDDWPKKDQPKK"
     gene            complement(20337..21464)
                     /gene="dapE"
                     /locus_tag="IT892_000547"
     CDS             complement(20337..21464)
                     /gene="dapE"
                     /locus_tag="IT892_000547"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HAP3133790.1"
                     /translation="MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMD
                     FADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKG
                     SLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKVVEALMARNERLDYCLV
                     GEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIE
                     WDQGNEFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLE
                     KHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMG
                     AQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA"
     gene            complement(21468..21824)
                     /locus_tag="IT892_000548"
     CDS             complement(21468..21824)
                     /locus_tag="IT892_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HAP3133791.1"
                     /translation="MVTLYGIKNCDTIKKARRWLEANNIDYRFHDYRVDGLDSELLNG
                     FINELGWEALLNTRGTTWRKLDETTRNKIIDAASAAALMTEMPAIIKRPLLCAPGKPM
                     LLGFSDSSYQQFFHEV"
     gene            22205..22264
                     /gene="ypfM"
                     /locus_tag="IT892_000549"
     CDS             22205..22264
                     /gene="ypfM"
                     /locus_tag="IT892_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YpfM"
                     /protein_id="HAP3133792.1"
                     /translation="MIERELGNWKDFIEVMLRK"
     gene            complement(22363..25476)
                     /gene="acrD"
                     /locus_tag="IT892_000550"
     CDS             complement(22363..25476)
                     /gene="acrD"
                     /locus_tag="IT892_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease AcrD"
                     /protein_id="HAP3133793.1"
                     /translation="MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVR
                     VTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDE
                     AVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
                     NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQ
                     LGGTPSVDKQALNATINAQSLLQTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYD
                     YLSRFNGKPASGLGVKLASGANEMATAELVLNRLDELAQYFPHGLEYKVAYETTSFVK
                     ASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNT
                     LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVLVAMILTPALCATLLKPLKKGEHHGQ
                     KGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFLPLE
                     DRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVA
                     RMFIRLKDWSERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDME
                     LQDHAGAGHDALMTARNQLLALAAENPELTRVRHNGLDDSPQLQIDIDQRKAQALGVA
                     IDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP
                     FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLE
                     WTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLAT
                     WMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPI
                     LMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF
                     PLKPRPE"
     gene            complement(25640..27340)
                     /gene="narQ"
                     /locus_tag="IT892_000551"
     CDS             complement(25640..27340)
                     /gene="narQ"
                     /locus_tag="IT892_000551"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarQ"
                     /protein_id="HAP3133794.1"
                     /translation="MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAIN
                     IAGSLRMQSYRLGYDLQSGSPQLNAHRQLFQQALHSPVLTNLNVWYVPEAVKTRYAHL
                     NANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIG
                     IFTLVFFTLRRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTSLPNELGLLAKTFNQM
                     SSELHKLYRSLEASVEEKTRDLHEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRD
                     NEAAEYLELNVGENWRISEGQPNPELPMQILPVTMQETVYGELHWQNSHVSSSEPLLN
                     SVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIP
                     EDNATAQSIMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAK
                     LTLDCRLPTLALDAQMQVHLLQIIREAVLNAMKHANASEIAVSCVTAPDGNHTVYIRD
                     NGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEGEESQLM
                     "
     gene            27546..29525
                     /gene="aegA"
                     /locus_tag="IT892_000552"
     CDS             27546..29525
                     /gene="aegA"
                     /locus_tag="IT892_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     AegA"
                     /protein_id="HAP3133795.1"
                     /translation="MNRFIMANSQQCLGCHACEIACVMAHNDEQHVLSQHHFHPRITV
                     IKHQQQRSAVTCHHCEDAPCARSCPNGAISHVDDSIQVNQQKCIGCKSCVVACPFGTM
                     QIVLTPVAAGKVKATAHKCDLCAGRENGPACVENCPADALQLVTDAALSGMAKSRRLR
                     TARQEHQPWHASTAAQEMPVMSKVEQMQATPARGEPDKLAIEARKTGFDEIYLPFRVD
                     QAQREASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITG
                     RVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDLSHVTKVDKRVAIIG
                     AGPAGLACADVLTRNGVEVTVYDRHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGI
                     HFELNCEVGKDVSLDSLLEQYDAVFVGVGTYRSMKAGLPNEDAPGVYDALPFLIANTK
                     QVMGLEELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPG
                     SKKEVKNAREEGANFEFNVQPVALELNEQGHVCGIRFLRTRLGEPDAQGRRRPVPVEG
                     SEFVMPADAVIMAFGFNPHGMPWLESHGVMVDKWGRIIADVESQYRYQTTNPKIFAGG
                     DAVRGADLVVTAMAEGRHAAQGIIDWLGVKSVKSH"
     gene            29593..30168
                     /gene="nudK"
                     /locus_tag="IT892_000553"
     CDS             29593..30168
                     /gene="nudK"
                     /locus_tag="IT892_000553"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphatase NudK"
                     /protein_id="HAP3133796.1"
                     /translation="MTQQITLIKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDR
                     GNGATILLYNAKKKTVVLIRQFRVATWVNGNESGQLIETCAGLLDNDEPEVCIRKEAI
                     EETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDSQRANAGGGVEDEDIEVLELPF
                     NKALEMIKTGEIRDGKTVLLLNYLQMSHLMD"
     gene            30294..31337
                     /locus_tag="IT892_000554"
     CDS             30294..31337
                     /locus_tag="IT892_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1176 domain-containing protein"
                     /protein_id="HAP3133797.1"
                     /translation="MRYRIFLLFFFALLPTSLVWAAPAQRAFSDWQVTCNNQNFCVAR
                     NTGDHNGLVMTLSRSAGAHTDAVLRIERGGLKSPDASEGEIAPRLLLDGEPLALSGDK
                     WRISPWLLVTDDTATITAFLQMIQEGKAITLRDGNQTISLSGLKAALLFIDAQQKRVG
                     SETAWIKKGDEPPLSVPPAPALKEVAVVNPTPTPLSLEERNDLLDYGNWRMNGLRCSL
                     DPLRREVNVTALTDDKALMMISCEAGAYNTIDLAWIVSRKKPLASRPVRLRLPFNSGQ
                     ETNELELMNATFDEKSRELVTLAKGRGLSDCGIQARWRFDGQRFRLVRYAAEPTCDNW
                     HGPDAWPTLWITR"
     gene            complement(31440..33443)
                     /gene="tkt"
                     /locus_tag="IT892_000555"
     CDS             complement(31440..33443)
                     /gene="tkt"
                     /locus_tag="IT892_000555"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAP3133798.1"
                     /translation="MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFL
                     KHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEI
                     GYTPGVETTTGPLGQGLANAVGLAIAARTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
                     ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGH
                     DPQAVKKAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKL
                     GWHHPPFEIPKEIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPK
                     DWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGS
                     VSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALM
                     KARQIMVYTHDSIGLGEDGPTHQAVEQLASLRLTPNFSTWRPCDQVEAAVGWKLAVER
                     HNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEMEITLQA
                     AEKLAGEGRNVRVVSLPSTDIFDAQDEEYRESVLPSNVAARVAVEAGIADYWYKYVGL
                     KGAIVGMTGYGESAPADKLFPFFGFTAENIVAKAHKVLGVKGA"
     gene            complement(33463..34413)
                     /gene="tal"
                     /locus_tag="IT892_000556"
     CDS             complement(33463..34413)
                     /gene="tal"
                     /locus_tag="IT892_000556"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HAP3133799.1"
                     /translation="MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGL
                     SQYEHLIDDAIAWGRKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSF
                     DKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
                     AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYE
                     TIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMS
                     EAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL"
     gene            34702..36981
                     /gene="maeB"
                     /locus_tag="IT892_000557"
     CDS             34702..36981
                     /gene="maeB"
                     /locus_tag="IT892_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxaloacetate-decarboxylating
                     malate dehydrogenase"
                     /protein_id="HAP3133800.1"
                     /translation="MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVA
                     APCLEIEKDPLKAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFA
                     GIDVFDIEVDELDPDKFIEVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
                     DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVV
                     CDSKGVIYQGREPNMAETKAAYAVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKK
                     MARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDV
                     GATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKI
                     APAVAKAAMESGVATRPIADFDVYIDKLTEFVYKTNLFMKPIFSQARKAPKRVVLPEG
                     EEARVLHATQELVTLGLAKPILIGRPNVIEMRIQKLGLQIKAGVDFEIVNNESDPRFK
                     EYWTEYFQIMKRRGVTQEQAQRALISNPTVIGAIMVQRGEADAMICGTVGDYHEHFSV
                     VKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNDEPDAEELAEITLMAAETVRRFG
                     IEPRVALLSHSNFGSSDCPSSSKMRQALELVRERAPELMIDGEMHGDAALVEAIRSDR
                     MPDSPLKGSANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVAKPVHVLTPIASV
                     RRIVNMVALAVVEAQTQPL"
     gene            37274..37609
                     /gene="eutS"
                     /locus_tag="IT892_000558"
     CDS             37274..37609
                     /gene="eutS"
                     /locus_tag="IT892_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HAP3133801.1"
                     /translation="MDKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIM
                     TLTPGETAMIAGDLALKAADVHIGFLDRFSGALVIYGSVGAVEEALSQTVSGLGRLLN
                     YTLCEMTKS"
     gene            37622..38101
                     /gene="eutP"
                     /locus_tag="IT892_000559"
     CDS             37622..38101
                     /gene="eutP"
                     /locus_tag="IT892_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutP"
                     /protein_id="HAP3133802.1"
                     /translation="MKRIAFVGTVGAGKTTLFNALQGDYTLARKTQAVEFNDKGDIDT
                     PGEYFSHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLLDIGVSKRQIAVISKTD
                     MPDADVAATRKLLLETGFEEPIFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHSE"
     gene            38076..38777
                     /gene="eutQ"
                     /locus_tag="IT892_000560"
     CDS             38076..38777
                     /gene="eutQ"
                     /locus_tag="IT892_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutQ"
                     /protein_id="HAP3133803.1"
                     /translation="MKKLITANDIREAHARGEQAMSVVLRASIITPEAREVADLLGFT
                     ITECDESTPVTASVPACVPADKTESQRIRETIIAQLPEGQFTESLVAQLMEKVMKEKQ
                     SLEQGAMQPSFKSVTGKGGIKVIDGSSVKFGRFDGAEPHCVGLTDLVTGDDGSSMAAG
                     FMQWENAFFPWTLNYDEIDMVLEGELHVRHEGETMIAKAGDVMFIPKGSSIEFGTTSS
                     VKFLYVAWPANWQSL"
     gene            38774..39577
                     /gene="eutT"
                     /locus_tag="IT892_000561"
     CDS             38774..39577
                     /gene="eutT"
                     /locus_tag="IT892_000561"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization cob(I)yrinic acid
                     a,c-diamide adenosyltransferase EutT"
                     /protein_id="HAP3133804.1"
                     /translation="MKDFITEAWLRANHTLSEGAEIHLPADSRLTPSARELLESRHLR
                     IKFIDEQGRLFVDDEQQQPQPVHGLTSSDEHRQACCELCRQPVAKKPDTLTHLSAEKM
                     VAKSDPRLGFRAVLDSTIALAVWLQIELAEPWQPWLADIRSRLGNIMRADALGEPLAC
                     QAIVGLSDEDLHRLSHQPLRYLGHDHLVPEASHGRDAALLNLLRTKVRETETVAAQVF
                     ITRSFEVLRPDILQALNRLSSTVYVMMILSVTKQPLTVKQIQQRLGETQ"
     gene            39574..40590
                     /gene="pta"
                     /locus_tag="IT892_000562"
     CDS             39574..40590
                     /gene="pta"
                     /locus_tag="IT892_000562"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAP3133805.1"
                     /translation="MIIERCRELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPIL
                     VANPFELRQFALSHGVAMDGLQVIDPHGNLAMREEFALRWLARAGEKTPPDALEKLTD
                     PLMFAAAMVSAGTADVCIAGNLSSTANVLRAGLRIIGLQPGCKTLSSIFLMLPQYSGP
                     ALGFADCSVVPQPTAAQLADIALASAETWRAITGEEPRVAMLSFSSNGSARHPCVANV
                     QQATEIVRERAPKLVVDGELQFDAAFVPEVAAQKAPASPLQGKANVMVFPSLEAGNIG
                     YKIAQRLGGYRAVGPLIQGLAAPMHDLSRGCSVQEIIELALVAAVPRQTEVNRESSLQ
                     TLVE"
     gene            40629..40922
                     /gene="eutM"
                     /locus_tag="IT892_000563"
     CDS             40629..40922
                     /gene="eutM"
                     /locus_tag="IT892_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HAP3133806.1"
                     /translation="MEALGMIETRGLVALIEASDAMVKAARVKLVGVKQIGGGLCTAM
                     VRGDVAACKAATDAGAAAAQRIGELVSVHVIPRPHGDLEEVFPIGLKGDSSNL"
     gene            41029..41316
                     /gene="eutN"
                     /locus_tag="IT892_000564"
     CDS             41029..41316
                     /gene="eutN"
                     /locus_tag="IT892_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutN"
                     /protein_id="HAP3133807.1"
                     /translation="MKLAVVTGQIVCTVRHHGLAHDKLLMVEMIDPQGNPDGQCAVAI
                     DNIGAGTGEWVLLVSGSSARQAHKSETSPVDLCVIGIVDEVVSGGQVIFHK"
     gene            41328..42731
                     /locus_tag="IT892_000565"
     CDS             41328..42731
                     /locus_tag="IT892_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase EutE"
                     /protein_id="HAP3133808.1"
                     /translation="MNQQDIEQVVKAVLLKMQSSDTPPAAVHEMGVFASLDDAVAAAK
                     IAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTP
                     GVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAP
                     HPAAKKVSQRAITLLNQAIVAAGGPENLLVTVANPDIETAQRLFKFPGIGLLVVTGGE
                     AVVEAARKHTNKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNIICADEKVLI
                     VVDSVADELMRLMEGQHAVKLTAEQAQQLQPVLLKNIDERGKGTVSRDWVGRDAAKIA
                     AAIGLKVPEQTRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHH
                     TAAMHSRNIENMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSAR
                     TFVRLRRCVLVDAFRIV"
     gene            42742..43578
                     /gene="eutJ"
                     /locus_tag="IT892_000566"
     CDS             42742..43578
                     /gene="eutJ"
                     /locus_tag="IT892_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HAP3133809.1"
                     /translation="MAHDEQWLTPRLHIAATLCNQTPAATESPLWLGVDLGTCDVVSM
                     VVDRDGQPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGRRFSHAATSFPP
                     GTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVT
                     YSADEATGGHHISLTLAGNRRISLEEAEQYKRGHGEEIWPAVKPVYEKMADIVARHIE
                     GQGITDLWLAGGSCMQPGVAELFCKQFPALQVHLPQHSLFMTPLAIASSGREKAEGIY
                     AK"
     gene            43568..44755
                     /gene="eutG"
                     /locus_tag="IT892_000567"
     CDS             43568..44755
                     /gene="eutG"
                     /locus_tag="IT892_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization ethanol dehydrogenase
                     EutG"
                     /protein_id="HAP3133810.1"
                     /translation="MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGAMSSCGQQA
                     QTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQL
                     RESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
                     GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAI
                     EAYSALNATPFTDSLAIGAIAMIGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAG
                     LGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRERFSQIGRALRTKKSDDRD
                     AINAVSELIAEVGIGKRLGDIGATSAHYGAWAQAALEDICLRSNPRTASLEQIVGLYA
                     AAQ"
     gene            44925..46151
                     /gene="eutH"
                     /locus_tag="IT892_000568"
     CDS             44925..46151
                     /gene="eutH"
                     /locus_tag="IT892_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HAP3133811.1"
                     /translation="MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGS
                     GGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACD
                     MGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
                     GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVLIVAVLVALGLKFIPE
                     KMINGFQIFAKFLVALITLGLAAAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEV
                     IGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVATLANNIPMFGMMK
                     QMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLV
                     PKEDATAAKTEAEAQS"
     gene            46148..47551
                     /gene="eutA"
                     /locus_tag="IT892_000569"
     CDS             46148..47551
                     /gene="eutA"
                     /locus_tag="IT892_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HAP3133812.1"
                     /translation="MNTRQLLSVGIDIGTTTTQVIFSHLELVNRAAVSQVPRYEFIKR
                     EISWQSPVFFTPVDKQGGLKEAELKTLILEQYQAAGIAPESVDSGAIIITGESAKTRN
                     ARPAVMTLSQSLGDFVVASAGPHLESVIAGHGAGAQTLSEQRLCRVLNIDIGGGTANY
                     ALFDAGKISGTACLNVGGRLLETDSQGRVVYAHKPGQMIVDECFGAGTDARSLTGAQL
                     VQVTRRMAELIVEVIDGTLSPLAQALMQTGLLPAGVTPEIITLSGGVGECYRHQPADP
                     FCFADIGPLLATALHDHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEGVQL
                     PLRNLPVAIPIDETDLVSAWQQALIQLDLDPNSDAYVLALPASLPVRYAAVLTVINAL
                     VDFVARFPNPHPLLVVAGQDFGKALGMLLRPQLQQLPLAVIDEVIVRAGDYIDIGTPL
                     FGGSVVPVTVKSLAFPS"
     gene            47563..48924
                     /locus_tag="IT892_000570"
     CDS             47563..48924
                     /locus_tag="IT892_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HAP3133813.1"
                     /translation="MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQER
                     VAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLS
                     DETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSAR
                     LQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNI
                     PTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFN
                     RIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEY
                     LYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIM
                     GMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKWAGDPS
                     LFF"
     gene            48945..49832
                     /locus_tag="IT892_000571"
     CDS             48945..49832
                     /locus_tag="IT892_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HAP3133814.1"
                     /translation="MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTTCTTPVTSESCA
                     LDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRS
                     KDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPD
                     VQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILG
                     AKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVI
                     VDLAKRMLEQKASGINMTR"
     gene            49842..50501
                     /gene="eutL"
                     /locus_tag="IT892_000572"
     CDS             49842..50501
                     /gene="eutL"
                     /locus_tag="IT892_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HAP3133815.1"
                     /translation="MPALDLIRPSVTAMRVIASVNAEFARELKLPPHIRSLGLISADS
                     DDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDA
                     MVAHIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATY
                     GIDAALKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQR
                     A"
     gene            50514..51014
                     /gene="eutK"
                     /locus_tag="IT892_000573"
     CDS             50514..51014
                     /gene="eutK"
                     /locus_tag="IT892_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311336.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutK"
                     /protein_id="HAP3133816.1"
                     /translation="MINALGLLEVDGMVAAIDAADAMLKAANVRLLSHEVLDPGRLTL
                     VVEGDLAACRAALDAGCAAAMRTGRVISRKEIGRPDDDTQWLVTGFNRQPKQPVKEPD
                     APVIVVESADELLALLTSVRQGMTAGEVAAHFGWPLEKARNALEQLFSAGTLRKRSSR
                     YRLKPH"
     gene            51060..52112
                     /gene="eutR"
                     /locus_tag="IT892_000574"
     CDS             51060..52112
                     /gene="eutR"
                     /locus_tag="IT892_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator EutR"
                     /protein_id="HAP3133817.1"
                     /translation="MKKTRTANLHHLYHEPLPENLKLTPKVEVDNVHQRQTTDVYEHA
                     LTITAWQQIYDQLHPGKFHGEFTEILLDDIQVFREYTGLALRQSCLVWPNSFWFGIPA
                     TRGEQGFIGSQCLGSAEIATRPGGTEFELSTPDDYTILGVVLSEDVITRQANFLHNPD
                     RVLHMLRSQSALEVKEQHKAALWGFVQQALATFCENPENLHQPAVRKVLGDNLLMAMG
                     AMLEEAQPMVTAESISHQSYRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNA
                     FHAILGIGPNAWLKRIRLNAVRRELISPWSQSTTVKDAAMQWGFWHLGQFATDYQQLF
                     AEKPSLTLHQRMREWG"
     gene            complement(52118..53017)
                     /gene="hemF"
                     /locus_tag="IT892_000575"
     CDS             complement(52118..53017)
                     /gene="hemF"
                     /locus_tag="IT892_000575"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HAP3133818.1"
                     /translation="MKPDAHQVKQFLLNLQDTICQQLSTVDGTEFVEDSWQREAGGGG
                     RSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYV
                     PTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEDDAIHWHRTARDLCQPFGEDVY
                     PRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTNAYLPIVE
                     RRKTMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEY
                     DYQPEAGSPEAALSEFIKVRDWV"
     gene            complement(53021..53890)
                     /gene="amiA"
                     /locus_tag="IT892_000576"
     CDS             complement(53021..53890)
                     /gene="amiA"
                     /locus_tag="IT892_000576"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiA"
                     /protein_id="HAP3133819.1"
                     /translation="MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKDEPLKTSNG
                     HSKPKAKKSGGKRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDA
                     RLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
                     KYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKL
                     HSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISFF
                     HWFDNQKAHSRKR"
     gene            54104..54529
                     /locus_tag="IT892_000577"
     CDS             54104..54529
                     /locus_tag="IT892_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase YpeA"
                     /protein_id="HAP3133820.1"
                     /translation="MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSL
                     FLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPK
                     IQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY"
     gene            54516..54965
                     /locus_tag="IT892_000578"
     CDS             54516..54965
                     /locus_tag="IT892_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2919 domain-containing protein"
                     /protein_id="HAP3133821.1"
                     /translation="MKSTEFHPVHYDAHGRLRLPLLFWLVLLLQARTWVLFVIAGASR
                     EQGTALLNLFYPDHDNFWLGLIPGIPAVLAFLLSGRRASFPRIWHVLYFLLLLAQVVL
                     LCWQPWLWLNGESVSGIGLALVVADIVALIWLLTNRRLRACFNEEKE"
     gene            55026..55601
                     /locus_tag="IT892_000579"
     CDS             55026..55601
                     /locus_tag="IT892_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpoE-regulated lipoprotein"
                     /protein_id="HAP3133822.1"
                     /translation="MISLRLMLCAMPLMLTGCSTMSSVNWSAANPWNWFGSSTKVSEQ
                     GVGELTASTPLQEQAIADALDGDYRLRSGMKTANGNVVRFFEVMKGDNVAMVINGDQG
                     TISRIDVLDSDIPADSSVKIGTPFSDLYSKAFGNCQKADGDDNRAVECKAEGSQHISY
                     QFSGEWSGPEGLMPSDDTLKNWKVSKIIWRR"
     gene            55697..56596
                     /gene="yfeX"
                     /locus_tag="IT892_000580"
     CDS             55697..56596
                     /gene="yfeX"
                     /locus_tag="IT892_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311329.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphyrinogen peroxidase"
                     /protein_id="HAP3133823.1"
                     /translation="MSQVQSGILPEHCRAAIWIEANVKGEVDALRAASKTFADKLATF
                     EAKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFPGYGKGLAPTTQFDVLIHILSLR
                     HDVNFSVAQAAMEAFGDCIEVKEEIHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
                     KDGVDAGGSYVFVQRWEHNLKQLNRMSVHDQEMMIGRTKEANEEIDGDERPETSHLTR
                     VDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAM
                     LRFTKPVTGGYYFAPSLDKLMAL"
     gene            56796..57254
                     /gene="tnpA"
                     /locus_tag="IT892_000581"
     CDS             56796..57254
                     /gene="tnpA"
                     /locus_tag="IT892_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAP3133824.1"
                     /translation="MGNEKSLAHTRWNCKYHIVFAPKYRRQVFYREKRRAIGSILRKL
                     CEWKSVRILEAECCADHIHMLVEIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRN
                     REFWCRGYYVDTVGKNTAKIQDYIKHQLEEDKMGEQLSIPYPGSPFTGRK"
     gene            complement(57365..58666)
                     /gene="pbp4b"
                     /locus_tag="IT892_000582"
     CDS             complement(57365..58666)
                     /gene="pbp4b"
                     /locus_tag="IT892_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin binding protein PBP4B"
                     /protein_id="HAP3133825.1"
                     /translation="MKRTMLYLSLLAVSCSVSAAKYPVLTESSPEKAGFNVERLNQMD
                     RWISQQVDAGYPGVNLLIIKDNQIVYRKAWGAAKKYDGSVLMEQPVKATTGTLYDLAS
                     NTKMYATNFALQKLMSEGKLHPDDRIAKYIPGFADSPNDTIKGKNTLRISDLLHHSGG
                     FPADPQYPNKAVAGALYSQDKGQTLEMIKRTPLEYQPGSKHIYSDVDYMLLGFIVESV
                     TGQPLDRYVEESIYRPLGLTHTVFNPLLKGFKPQQIAATELNGNTRDGVIHFPDIRTS
                     TLWGQVHDEKAFYSMGGVSGHAGLFSNTGDIAVLMQTMLNGGGYGDVQLFNAETVKMF
                     TTSSKEDATFGLGWRVNGNATMTPTFGTLASPQTYGHTGWTGTVTVIDPVNHMAIVML
                     SNKPHSPVADPQKNPNMFESGQLPIATYGWVVDQVYAALKQ"
     gene            complement(58671..60095)
                     /gene="murP"
                     /locus_tag="IT892_000583"
     CDS             complement(58671..60095)
                     /gene="murP"
                     /locus_tag="IT892_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylmuramic acid transporter subunit
                     IIBC"
                     /protein_id="HAP3133826.1"
                     /translation="MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVD
                     PNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQL
                     KAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALN
                     FMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPTATTGYYAGFHDF
                     FGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIM
                     PLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNS
                     LFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMK
                     PFITACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAG
                     GILVAWVCGFIFTTLFGCRNVNLD"
     gene            complement(60099..60995)
                     /gene="murQ"
                     /locus_tag="IT892_000584"
     CDS             complement(60099..60995)
                     /gene="murQ"
                     /locus_tag="IT892_000584"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP3133827.1"
                     /translation="MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERV
                     LPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGG
                     EYAIQHAVEGAEDSREGGVNDLKNINLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
                     TVGISCNPGSAVSTTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGK
                     VFGNLMVDVVATNEKLHVRQVNIVKNATGCSAEQAEAALVACERNCKTAIVMVLKNLD
                     AAEAKKRLDQHGGFIRQVLDKE"
     gene            61159..62016
                     /gene="murR"
                     /locus_tag="IT892_000585"
     CDS             61159..62016
                     /gene="murR"
                     /locus_tag="IT892_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MurR"
                     /protein_id="HAP3133828.1"
                     /translation="MLYLTKIRNAESEFTGNEQKIADFLRANVSELKSVSSRKMAKLL
                     GISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIA
                     RKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
                     GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSL
                     TDSPLRRLAHYTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIER
                     SSELTQRLK"
     gene            62145..62936
                     /gene="ucpA"
                     /locus_tag="IT892_000586"
     CDS             62145..62936
                     /gene="ucpA"
                     /locus_tag="IT892_000586"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416921.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase UcpA"
                     /protein_id="HAP3133829.1"
                     /translation="MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEK
                     LADELCGRGHRCTAVVADVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMS
                     DEDRDFHIDINIKGVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKA
                     AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAIPM
                     RRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPETVSVGI"
     gene            63107..64123
                     /locus_tag="IT892_000587"
     CDS             63107..64123
                     /locus_tag="IT892_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3133830.1"
                     /translation="MAVNLLKKNSLALVASLLLAGHVQATELLNSSYDVSRELFAALN
                     PPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKL
                     IPADWQTRLPNNSSPFYSTMGFLVRKGNPKNIHDWNDLVRSDVKLIFPNPKTSGNARY
                     TYLAAWGAADKADGGDKAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFE
                     SEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKNVQANGTEKAAKAYLNWLYSPQA
                     QTIITDYYYRVNNPEVMDKLKDKFPQTELFRVEDKFGSWPEVMKTHFTSGGELDKLLA
                     AGRN"
     gene            64123..64956
                     /gene="cysT"
                     /locus_tag="IT892_000588"
     CDS             64123..64956
                     /gene="cysT"
                     /locus_tag="IT892_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysT"
                     /protein_id="HAP3133831.1"
                     /translation="MFAVSSRRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLSEMSW
                     AQYWEVITNPQVVAAYKVTLLSAFVASIFNGVFGLLMAWILTRYRFPGRTLLDALMDL
                     PFALPTAVAGLTLASLFSVNGFYGEWLAKFDIKVTYTWLGIAVAMAFTSIPFVVRTVQ
                     PVLEELGPEYEEAAETLGATRWQSFCKVVLPELSPALVAGVALSFTRSLGEFGAVIFI
                     AGNIAWKTEVTSLMIFVRLQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRRVVG
                     H"
     gene            64956..65831
                     /gene="cysW"
                     /locus_tag="IT892_000589"
     CDS             64956..65831
                     /gene="cysW"
                     /locus_tag="IT892_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysW"
                     /protein_id="HAP3133832.1"
                     /translation="MAEVTQLKRYDARPINWGKWFLIGIGMLVSAFILLVPMIYIFVQ
                     AFSKGLMPVLQNLADPDMLHAIWLTVMIALIAVPVNLVFGILLAWLVTRFNFPGRQLL
                     LTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFSWPGMVLVTIFVTCPF
                     VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEF
                     GAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRL
                     ENQEKRAQQEEHHEH"
     gene            65821..66918
                     /gene="cysA"
                     /locus_tag="IT892_000590"
     CDS             65821..66918
                     /gene="cysA"
                     /locus_tag="IT892_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter ATP-binding
                     protein CysA"
                     /protein_id="HAP3133833.1"
                     /translation="MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL
                     LRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQHYALFRHMTVFDNIAFGLTVL
                     PRRERPNAAAIKAKVTKLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL
                     DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQA
                     DAPDQVWREPATRFVLEFMGEVNRLQGTIRGGQFHVGAHRWPLGYTPAYQGPVDLFLR
                     PWEVDISRRTSLDSPLPVQVLEASPKGHYTQLVVQPLGWYNEPLTVVMHGDDAPQRGE
                     RLFVGLQHARLYNGDERIETRDEELALAQSA"
     gene            67052..67963
                     /gene="cysM"
                     /locus_tag="IT892_000591"
     CDS             67052..67963
                     /gene="cysM"
                     /locus_tag="IT892_000591"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase B"
                     /protein_id="HAP3133834.1"
                     /translation="MSTLEQTIGNTPLVKLQRMGPNNGSEIWLKLEGNNPAGSVKDRA
                     ALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAA
                     MRAYGAELILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQ
                     QTGGRITHFVSSMGTTGTITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPAEYLP
                     GIFNASLVDEVLDIHQREAENTMRELAVREGIFCGVSSGGAVAGALRVAKANPGAVVV
                     AIICDRGDRYLSTGVFGEEHFSQGAGI"
     gene            complement(67966..68334)
                     /locus_tag="IT892_000592"
     CDS             complement(67966..68334)
                     /locus_tag="IT892_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeK family protein"
                     /protein_id="HAP3133835.1"
                     /translation="MKKIICLVITLLMTLPVYAKLTAHEEARINAMLEGLAQKKDLIF
                     VRNGDEHTCDEAVSHLRLKFGNTRNRIDTAEQFIDKVASSSSITGKPYIVKMPGKSDE
                     NAQPFLHALIAQTDKTVPAQ"
     gene            68439..69290
                     /gene="pdxK"
                     /locus_tag="IT892_000593"
                     /gene_synonym="thiJ"
     CDS             68439..69290
                     /gene="pdxK"
                     /locus_tag="IT892_000593"
                     /gene_synonym="thiJ"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine/pyridoxal/pyridoxamine kinase"
                     /protein_id="HAP3133836.1"
                     /translation="MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGL
                     NVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQ
                     IKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
                     FELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNV
                     ISHSRVKTDLKGTGDLFCAQLISGLLKGKALNDAVHRAGLRVLEVMRYTQQHESDELI
                     LPPLAEA"
     gene            complement(69332..69841)
                     /gene="crr"
                     /locus_tag="IT892_000594"
     CDS             complement(69332..69841)
                     /gene="crr"
                     /locus_tag="IT892_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP3133837.1"
                     /translation="MGLFDKLKSLVSDDKKDTGTIEIIAPLSGEIVNIEDVPDVVFAE
                     KIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGE
                     GFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
                     ETPVIRIKK"
     gene            complement(69882..71609)
                     /gene="ptsI"
                     /locus_tag="IT892_000595"
     CDS             complement(69882..71609)
                     /gene="ptsI"
                     /locus_tag="IT892_000595"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase
                     PtsI"
                     /protein_id="HAP3133838.1"
                     /translation="MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFL
                     SGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADA
                     AAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA
                     ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYL
                     ILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIG
                     TVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTM
                     DIGGDKELPYMNFPKEENPFLGWRAIRIAMDRKEILRDQLRAILRASAFGKLRIMFPM
                     IISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFS
                     IGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGD
                     ERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVN
                     KFIEEKTIC"
     gene            complement(71654..71911)
                     /gene="ptsH"
                     /locus_tag="IT892_000596"
     CDS             complement(71654..71911)
                     /gene="ptsH"
                     /locus_tag="IT892_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein Hpr"
                     /protein_id="HAP3133839.1"
                     /translation="MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASA
                     KSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE"
     gene            complement(72295..73266)
                     /gene="cysK"
                     /locus_tag="IT892_000597"
     CDS             complement(72295..73266)
                     /gene="cysK"
                     /locus_tag="IT892_000597"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAP3133840.1"
                     /translation="MSKIFEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCR
                     IGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRK
                     LLKALGANLVLTEGAKGMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPE
                     IWEDTDGQVDVFIAGVGTGGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGE
                     EIKPGPHKIQGIGAGFIPANLDLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGA
                     AVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ"
     gene            complement(73451..74212)
                     /gene="cysZ"
                     /locus_tag="IT892_000598"
     CDS             complement(73451..74212)
                     /gene="cysZ"
                     /locus_tag="IT892_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter CysZ"
                     /protein_id="HAP3133841.1"
                     /translation="MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMG
                     GAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAP
                     FNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIP
                     GIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSL
                     FTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR"
     gene            74442..75440
                     /gene="zipA"
                     /locus_tag="IT892_000599"
     CDS             74442..75440
                     /gene="zipA"
                     /locus_tag="IT892_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA"
                     /protein_id="HAP3133842.1"
                     /translation="MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRM
                     KSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPR
                     QPVQQPPEAQVPPQHAPRPAQPVQQPVQQPAYQPQPEQPLQQPVSPQVASAPQPVHSA
                     PQPAQQAFQSAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLN
                     SIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQV
                     PSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA"
     gene            75511..77526
                     /gene="ligA"
                     /locus_tag="IT892_000600"
     CDS             75511..77526
                     /gene="ligA"
                     /locus_tag="IT892_000600"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAP3133843.1"
                     /translation="MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRE
                     LETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRL
                     KSNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH
                     GENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKR
                     PLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEED
                     RPTLGFDIDGVVIKVNSLTQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRT
                     GAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVL
                     SERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMD
                     VDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTF
                     ARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAE
                     ESNRNVISELLAEGVHWPEPIIINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVEL
                     GAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS"
     gene            77528..77746
                     /locus_tag="IT892_000601"
     CDS             77528..77746
                     /locus_tag="IT892_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133844.1"
                     /translation="MEKEQLIEIANTIMPFGKYKGRRLIDLPEEYLLWFARKDEFPAG
                     KLGELMQITLLIKTEGLTQLVQPLKRPL"
     gene            complement(77743..78741)
                     /locus_tag="IT892_000602"
     CDS             complement(77743..78741)
                     /locus_tag="IT892_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter"
                     /protein_id="HAP3133845.1"
                     /translation="MKLFRILDPFTLTLITVVLLASFFPARGDFVPFFENLTTAAIAL
                     LFFMHGAKLSREAIIAGGGHWRLHLWVMCSTFVLFPILGVLFAWWKPVNVDPMLYSGF
                     LYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNVHGAGGS
                     LEQVGKIMLQLLLPFVLGHLSRPWIGDWVSRNKKWIAKTDQTSILLVVYTAFSEAVVN
                     GIWHKVGWGSLLFIVVVSCVLLAIVIVVNVFMARRLGFNKADEITIVFCGSKKSLANG
                     IPMANILFPTSVIGMMVLPLMIFHQIQLMVCAVLARRYKHQTEQLQAQQESRANKA"
     gene            78831..79757
                     /locus_tag="IT892_000603"
     CDS             78831..79757
                     /locus_tag="IT892_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3133846.1"
                     /translation="MNYSLKQLKVFVTVAQEKSFSRAGERIGLSQSAVSHSVKELENH
                     TGVRLLDRTTREVVLTDAGQQLALRLERLLDELNSTLRDTGRMGQQLSGKVRVAASQT
                     ISAHLIPQCIAESHRRYPDIQFVLHDRPQQWVMESIRQGDVDFGIVIDPGPVSDLQCE
                     AILSEPFFLLCHRDSALAAEDYVPWQALQGAKLVLQDYASGSRPLIDAALARNGIQAN
                     IVQEIGHPATLFPMVAAGIGISILPALALPLPEGSPLVVKRITPVVERQLMLVRRKNR
                     SLSTAAQALWDVVRGQGRALMAGREGDPLYQI"
     gene            complement(79796..80560)
                     /locus_tag="IT892_000604"
     CDS             complement(79796..80560)
                     /locus_tag="IT892_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133847.1"
                     /translation="MKKHLFTLTLSSVLAIPAVSHAEFKGGFADIGVHYLDWTSRTTE
                     KSSTKSHKDDFGYLEFEGGANFSWGEMYGFFDWENFYNGRHNKPGSEQRYTFKNTNRI
                     YLGDTGFNFYLHAYGTYGSANRVNFHDDMFLYGIGYNFTGSGWWFKPFFAKRYTDQTY
                     YTGDNGYVAGWVAGYSFMLGSEKFTLTNWNEYEFDRDATYAAGNGGKEGLNGAVALWW
                     NATSHITTGIQYRYADDKLGEDFYQDAIIYSIKFNF"
BASE COUNT        19309 a        20859 c        22142 g        18350 t
ORIGIN      
        1 gatcacctct ttgccggttc cggtttcacc acaaatcaac accgtactgt cgctcttcgc
       61 cacaatatct acctgctgga gcaaatcttc cattgcctgg ctttgataga taatgtcacc
      121 gacgcccaga ttcgaaagga gctgctcgct aagctggtgg ttttcttgct gcaagctttc
      181 ctgcaaatcg gtcatgctgc gccaggcatc ggcattgcca acggcaatag cgatgcgatc
      241 ggcaatatgt tgtagtagct ggcagttttc ctcactaaag agagtggaag aggtatgcgc
      301 cagcaacaat gcgcccggtg tatggttgcc aaaggtgagc ggtataagga gcgcagattc
      361 gcagccgtta gatgcaagta agtgtaataa cgggtcgcgt tgccagagaa acagatcgtc
      421 tgcacggtgc gtcaaggtcg gttgtcgggt ttgtagcgtt tgtgtcagca atacactttc
      481 gccaggcata cagcgtggca gacacgcaca atgtgaggca gaaagatcgc tgcaccacag
      541 gctgaacttc tcgttctttc gatgatcgcc cagtaccata ctgactgaag ccagaccgaa
      601 aaaatgatgg atctcacgag cgacgtcagc gatcagatcg tcgagatcaa gatgtgacaa
      661 cactgcatta gtgatatcca ccagtacccg atgatgatcg cgatctttct ccagcaaacg
      721 cagcgccacc tgctgttctt catcattgag ccatgattgc agaaccgggg tgattatccg
      781 cgccagccag ttaaacagtg tgcaatcctg gggagtaaaa cgactgccgt gggtgcgaat
      841 aaagcgtagc tccgccattc cactactgcc gagaaggacg gcgtggcgcg aataatcgac
      901 catctcactc tgatactctg ttgttgccgt cacatcgctg ccatcatcat ggtagcggta
      961 atagaagttg cttttgagaa catgcagttc aataagttgt accgggctga acggcggcgg
     1021 cagcgggatg aaggcgcgta ataaagacgc cttgccgtgt ttctgcgcta accgctccgc
     1081 gagcattccg tttaccgctt caattgttat tccttgcggc ggggcaaaca tcgcctcgtc
     1141 tgacatagcc atcaacagtc cttattaatg agaaatcctt ctcacgcaat ttttctggcc
     1201 atcagataga tggccggttc ctgcacaatt tcatccaaca gatgaatgaa ttgaatgcta
     1261 cgcgcctgcc acgccgacat cgcgtcatct gccagtggcg cgaatgcccg ggtcaacagg
     1321 gcggtgtggc tggcgtcaat aacaatctca ccaaaggtca tcacccccag catcttacgt
     1381 cgggcttgct cctcttcgac cagtgcaagc caatcttcgt attccgtcag tgggcagcgg
     1441 aaggcgacac tcaggcaatc aatcacgcca acgtgatgac cgatagccag cgagtaatac
     1501 attacctgag agctgtgttc cggcatctcg tcgctactgg cgacaaactt ttttcgcagc
     1561 gtccagaaaa caatttccct gcactcctca gccatgtaac ccccggagaa tgcgaaagag
     1621 ttgctgaacg atactattga gacgcggatc gtcagcttcg cgcaaccagg tgttaacccg
     1681 atttcctgta ggatcgtcgc ttaaatggcg caggagccga tcgcaaattt ctcgcccctg
     1741 acgatagccc gccagccgcc gcgcttctcg ctcaacggcg atacgctgtg atggcgggat
     1801 ctgcggccac agcggttgca tggtcacccc ggtgggatcg cgataatcca ccgcgtgaat
     1861 cttctgttgc agcaaaccga gcgccacggc gaaaccgtga atggtggcgg ccggtgttgg
     1921 cgggcagccg gggatccaaa catcaatggg gacaatggtg tcgctgccgc cccagacgct
     1981 gtagagatcg tggaaaatac cgccgccgac accacacgcg ctgtaggaaa cacagatttt
     2041 atgatcgggg gcagactcat atgcccgaag tgcaggcata cgcatcgctc gggtgactgc
     2101 gccagtaaat aacaaaatat cggcgtgacg tggtgatgaa acaaccttaa tgccaaaacg
     2161 ttctgcgtcg aatacgggtg tgatggcggc aaaaatttcg atttcgcagg cgttgcagcc
     2221 gccgcaatcg acgcgataaa cgtaagccga gcgacggata tcctgtagca aatgctgctt
     2281 tatcttttgc gtttgctcgt ccagcgttat gggctggctg acatgttgcg taagcactgg
     2341 actcatagct gctccttagc caccagcggt tcatctgtgt cgtcgttgat cagcgtcgcg
     2401 cgttgtttgc actccgggca gacgctcgct tgcgcccata acatttcgcg gttttgtggc
     2461 gcattttgtt gctgtgccaa caattcagca gccagtgcga cggttttttg cggggcaaac
     2521 gggcgttcgc aacggctgca acgttgtaga tggaacgtcg cgcgggtata gagatcggct
     2581 ttattggtga cggtcagttc aaagttattg gtaagctgaa tggctctggt cgggcacact
     2641 tcttcacaac gtccgcagta aatacaacgc cccagataga gctgccaggt gcgcgtattt
     2701 tgctggtcgt cggtctggat agtcagcgca tttgccggac aagcacaagc gcaggcaccg
     2761 caggcaatac attggctggg catcaggtcc ggtttcccgc gaaagcctgg gctgacctcc
     2821 agtggcgcga agggatattt caccgtcgcg gttccggcgc gcataatagt tttcagtaac
     2881 ttcagcatct tctgtcctta cttcagcggc gaacggttac gatcaatgcc gtagcgttcg
     2941 atctctttat acggcacggt ttttgactgg cgcttgcgca catcaaccag cgtcacacgg
     3001 tcggtacagg agtagcaggg atcaaggcta ccgataatca gcggtgcgtc agaaacggta
     3061 ttgccgcgca gcatgtaacg cagcactggc cagttggcgt aggtggcggc acgacagcgc
     3121 cagcggaaca atttttggtt atcaccgagc atgctccagt gcacgtcttc accacgtggc
     3181 gcttcaacaa agcccagcgc gaatgcgtga ggtttatagc taaagccttc ggtcagcagt
     3241 ggggtatccg gcatgttgtc gagggcaaat tccagcattg ccagcgaatc aaacgtctct
     3301 ttgacacgga ccatcacgcg ggagaagaca tcgccgccgg taaaggtaaa cagcgttttg
     3361 ggaatattgc cgtagtcggc gtaggggtga tcaaagcgca aatcacgggc aaaaccactg
     3421 ccgcggatca gcggcccgac agggctataa tcacgggcga tttgtcggtc gagaatgcca
     3481 atgccctgag tgcgttgttc catattcggc gtggcaagca gcatctctac cagctccgac
     3541 acgtcggcgc gcatctcgcg caccagtttc agcgtttgca gacgttgctc tttgagaata
     3601 tcgcggcgaa caccaccaat cagattcaga ccgtaggttt tacgcgaccc ggtcagcaat
     3661 tccgccatcg tcatcgactt ttcccgcacg cggaaaaatt gcataaagcc ggtatcaaat
     3721 ccaacaaaat ggcaggagag gccaaggttg agcaaatgac tatgcagccg ttcgacttcc
     3781 agcagaatcg agcgaatagt atgcgctcgt tgcggcacct caatccccag tgcattttca
     3841 accgagttgg tataggccac actgtgggca aaaccgcaaa tcccacacac gcggtcggat
     3901 aagaaggtca cttcgttgta gcccatccgc gtttctgcca gtttctccat gccgcgatgg
     3961 acataaaaca ggcggtaatc agcatcgaca atttgctcgc catccacaaa caagcggaag
     4021 tgacctggtt catcggaggt gatatgcagc gggccgacag ggataacccg cgcatcgctg
     4081 ttgccctcgt tgataaacgg atacgtttcg gtatcagtcg tcggttctgg gcgcagtcga
     4141 taatccatcg cgtctttgcg cagcggatgc atatcttccg gccagtcatc gggcaacacc
     4201 agccgacgct gatccggcag gccaaccgga atcagcccgt acatatcgcg aatttctcgc
     4261 tcgccccaga ccgcggcagg gacgcgcggt gtgactgacg gaaactcccg actgtcggca
     4321 tcgaccagtg ccttcaccac gatccagcat ttttcggccc cttccataga aagggcataa
     4381 taaaccgcgt aatgaccgtt aagtgtccgc tcgtcgttgc caaacaggac tggaagccag
     4441 ccatcatgtt gataataaag ataatgcaca acgtcaggca gcagattgat tttcaccgta
     4501 atggtgacct gttcaggcgt ttgtcgctct tcatccagca ccgcgccggg gaactgcgtt
     4561 ttcagggcgg cgagaatcgc ttcgccacga tttgacgatg aattaacgtt cactgtgttt
     4621 ctccgaaaca gatgcggtgc ctgaaggcaa aaaatcatgc caggtgctac gttgtgcagg
     4681 caggtcgtgc gtccctgaga ggactatagt ggaagcgccc gccaggatcc tgatgacagg
     4741 ttgtggaata tgcgttccca tcgccagcat catgaccagc agaatcacca ttggcgaggt
     4801 ggtcaaccag ccaagttcac cccggttaac ggcctgcggc ggtttcgcca ttaacacccg
     4861 cgcagccatc cgtaccaggc ccgccagcac cagcgttaac agcaataaca gcaggacgat
     4921 aagcagcaga tgattacgcg ccagtccggc ggtaacggtc ataaattcgc taagaaaaat
     4981 gttgaagggc ggcatcccgg ccagcgccag cgcaccgccg ccaaacaaca cggcggtaaa
     5041 tggcatgatt ttaagcattc cgcagacgac gttgagatcg cgcgtgccgt acttgagcag
     5101 tacattgccg gaaccgcaga acaacagcgt ttttgccaga ctgtggttta aggtgtgcag
     5161 cagcgcggca aaaattccca gcggcccgcc aatgcctagc gccaccgcga ccagtcccat
     5221 gttctccacg ctggagtacg ccagcagacg cttaatgtcc cgctgtacca gaatgaaaaa
     5281 tgccgccacg gcaaccgaca acatgccgaa gatgagcaac aaccggttgg ggaaatcgct
     5341 gccgatggcc tggcaaataa tgatgtaata gcgaatcagc accaacagcg cgcagttcag
     5401 caatacggcg gagagcaggg cgctgaccgg actcggcgct tcactgtgag catctggcag
     5461 ccaggcgtgc atggggaata gcccggtttt agtgccaaag ccaattagca cgaacacaaa
     5521 ggccaacagc attaatgttg ggtcaagcaa ggacgattgc ttaagaacct cgctccagaa
     5581 tatcgccatt tctgcctgcg gcataacgct ggcggcgttg gcgtatacca gcacggtacc
     5641 gaacagacca aaagcgacac caacagtaca aataatgatg tacttccatg cagcttccag
     5701 cgatgaacgc tgaccgtaaa tgcctaccag aaacgccgag cttaaggtgg tggcttcgat
     5761 cgccgcccac atcacaataa ggttattgct ggtgacaacc agcagcatgg tgaacaaaaa
     5821 cagatggaag aaaccgtagt aatcgcacag cgtaacgggt gaaagctcgc cgtgtgccac
     5881 ttcatgacgc atgtagccaa tcgagtaaac accggtgaga aagccaatca caccaagaat
     5941 ggcgaggaac aaaccgccca gaccatcaat atgaagccac agtcccgcag cgaatatttc
     6001 tcccgcatca gcggcagttt ggaccaccca cagtgccaga atcagtagca gtgtgatccc
     6061 taagctatgt aatactgtca ccgcgagagt cgcagagtgc ccccgtttcc gacaggcaaa
     6121 acagagcagc gaaaaaagca gcggcgtgag caggagtaaa gcgaacatca cagaataact
     6181 catctcatta tcccttcagc gcggtcaagt tattcacgtc cagcgtgccg tgggtacgcc
     6241 atatttttct tgccagtaac accatcacaa tgacggcgaa gatggcgtcg gtagcgatac
     6301 caatttccac cagttccggt gcacgccagg ctagaagcgc cagcaccaga tgggagccgt
     6361 tttccatcag gcagtaacca aaaatttgcc gcaggatatt gcgctggctg acaatgcaca
     6421 gcaggccaag cagaaaatga cctaacgcca ccgccagcgc cggtttcagc ccggtagcca
     6481 tcggtagctt cacgggctga acgacaaatg cgcaaagcag gacaattaac gccgcgagca
     6541 gtgtcatcat tgccggaccg aataacgctt tttccgggat gttctgggga atatttcgtg
     6601 cagcgtaagt catgattaac ggtaccagca gcactttggt gataaaggcg ctggcggacc
     6661 agatcagcag ttgctctgcg gcgaacaggc acgagagagt ggcgaaaata gacaccagca
     6721 ccagcgactg gcaggcgtaa aatccgcatg acaggcgata gcttttgacg ctaatcacaa
     6781 acagcgatgt cagcatcatc agtcccgcca gattatttac gatcatagaa ccggtcattc
     6841 atcatctcct tactgcaacc aggtcgcggc gattacgctg gaaatcagcg acatcacaat
     6901 cagtacaatc aacaccaggc gcattgatcc tggcagcggt gcggcatcgg cgacggcctc
     6961 gctcggtttg ccaggcacga cgcgaccaaa ccagcgaata aaccaggcga aactggcgac
     7021 cgattcaatc atcagcagaa tcatggcggg cagcaggatc cagtactcca ctgacaacgc
     7081 aaaaccggcg gcaaacagcg ggaatttact gaagaagccg ttgaacggcg gtacgccggt
     7141 aatcgccagc gctgccacgc agaaacccac gcctggcaac ggcagggtgt gcaatacgcc
     7201 acgcagacgc ggcaacaagc gcgtgccgca gctgtaactc agcgcacctg ctacaaggaa
     7261 aaacaggctt ttagcgaacg cgtggttgac gatgtaggcg atgctgccct ccagcgccag
     7321 ccgcgagccg aagatggaga gcgacaagcc gaaaaacatc cagccaagtt gagtgatggt
     7381 cgaccaggcc agcaaccgct tcatatcctg ctgtggcaaa tacatcagga agccataaag
     7441 aatggtgacc agtgccataa ccatgccaac gccgccaatc acatgcggga tattgccgcc
     7501 gtcgataatg gcacgggcaa aaatgtaaac gcccactttc accatcgatg cggcgtggag
     7561 ataggcgctg atcggtgttg gcgcttccat tgcatccggt agccacgctt gcatcggtag
     7621 ctgggccgat ttcccccacg cggcaaacag gatgccacca taaaccagat agcgtgcgtc
     7681 gccgtgtaac tcgctcatcg cgctaagcgc aaacgttccg gtctgcaaaa acagcgtggc
     7741 ggcggcaaga tacaacccca acgaaccgat atgggtaata agcaacgctt ttagtgccga
     7801 acgctgcgct ttatcgctct ggtaataact gatcaacgcc caggagcagc cgcccgtaat
     7861 ttcaaaaaac aacaactgac cgagcagcgt cgaagagagt accagtcccg ccatcgcgcc
     7921 gataaacagc agcaaaaatg cgtaataacg attcgtgccg ttatgcgggt gttcgcgatt
     7981 tttatccgtc agataacccg tggagtagat cgtgaccagc aaaccgagga acaccaccac
     8041 aaacagaatc agcgtactca cgcgatcaat gaccaggcca aacaacgcca catcccccac
     8101 gttgaccaac gtcaacgtga cggcaacttt atcggcctga taaaacgcgg agatcagtga
     8161 caacatgcac agcgtggtca gcgcggcgaa caaaaccccc cattcggcgg cccgacgttg
     8221 tggcgaaaac gaaacgacca gtgcgccgat aaaaggcagc aataacgtcg tcagagcaag
     8281 attttccata ttccgtcagt gctccttaca gaccggttaa ccagaagacc catgcaagcg
     8341 cagcaaggct gaagccaagc caggtcacat ggtgagtgag taaaaaacgc ccgcgtgcca
     8401 gcgtgttttc tgcgattgag gccagtacaa aaatcagcaa aaccttgagc agcgtaacga
     8461 caagtgaagt cagcaggcag gcgagagaaa gttcttgcgc gcgcccaaag ggcagaaaca
     8521 gggccacaaa cagtgctgcc atcacgatct gtttcagccc cagccccaac ttcgccagcg
     8581 ccagcccggc accggaatat tcggtcagcg ggccttcctg taattcctgt tctgcttcag
     8641 caacatcaaa gggaattttt cccatctcaa tgaagcaggc aaaaccacag gccagtaacg
     8701 ccagtacggt ggttagcggc gagttccagc ccgtcgccag cgtcttgctg atcatctcga
     8761 tatgcgtgga atccgctatc agcgccaata ccagcagtga gagaatgagc atgggttcga
     8821 ccagaatgcc gagcgtcaac tcgcgactgg caccgactcc cgcaaacggg cttccggtat
     8881 ccagcccgga aagagcaaag aaaaaacgaa acagggcaag aagatagata agggtgatca
     8941 gatcgccgcc gcccgcaaaa ggggaaacag taataaatag tggtagggcc atcgccagca
     9001 ccagcatgct gctgattaat acccacggca tcatgcggaa catcagacct gaagatgtcg
     9061 gcgcaacttc ctggcgttta aacagtttgt ggatatcgcg ataatcctgc cagatccccg
     9121 gtccgcgacg ggagtgcata cgcgcgcgta tctgccggga aatccccgta aaaagcgggg
     9181 ttagcgccag cagaatcacg gcctgtgcta acgcaaaaat gatcagatat ccgtcgcaaa
     9241 gagtttgtct catggtgatt tccttagacg gcaatagcga ttagcagcac aaccagtgcg
     9301 gcgaccacat acaggcaata gagacgaaag tcgccgcttt gcagatgctg tatttctttg
     9361 gccagccgtt gggtggcgct cacgatgggg cggatcaccc gctcatccca gaagggttct
     9421 gtgctctgag ccctggcggt gacgtgcgca agacctttgt tcagcctcag cgtagggtcg
     9481 agctgttgtc gtagacgaaa taacgcacaa aagaccacac gcagcggctg catcacgcca
     9541 ttgcctgacg gggccatcgc attttcccag ccgtagccgc atgcccaggc atctcctgtg
     9601 cgacgaaacg ctgcgcggcg cgaacgacac catagccagt aaaggccagg cagcaaaggc
     9661 atcgccagta gtaacagcaa cagtaatgag ggagtgaccc gtgtatgaaa cgtgccgggt
     9721 acaagtgcta ttccgctggc gacagtgacg ggaggggtat tggtaaacgc atgggcaatg
     9781 tgcattatct tcggtgccag ccaactggca ctaagcgcaa tgaatacgca gagtgccgcg
     9841 agcagtagca tggcgacgat catcgtattt ggcacttcct gtgcctcttc agcgtgtgta
     9901 ctgcgcggcg ctccacagaa agtaataccg tacattttga cgaagcacat tactgccagc
     9961 ccaccagtga ctgccagcat caccatagca ataggacccg caagttgtag cgctacggct
    10021 tccacacgac ttagtgagaa cagcgactgc caggtgtacc attcgctgat aaaaccattc
    10081 agcggaggaa tggctgatat cgcgaggcaa ccaatcaggc atgctgcggc tgtccacggc
    10141 atccgttttg ccagtgcccc cattttttcc atgtcgtggg tatgcaaacg cgaaataatc
    10201 gcacccgcgc cgagaaacag cagccctttg aacagcgcat ggttgagcag atgaaacagc
    10261 gcgccgagca gtccaacaac ggtgagcagc gggtcgtgca gtgacagacc gaccatcgcc
    10321 acaccgaccg ccagcaaaat aatgccgacg ttttcgacgg tactccaggc cagcagccgt
    10381 ttgatatcct gttccgccag cgcatacagc acgcccagga gcgcggagat tgcgccgatc
    10441 gccatcacca gaatgcccca ccacagcggc aaacccgttt gcgccagcag gtccatcgct
    10501 actttcagga tgccgaaaat accgattttg accattacgc cagacatcaa cgccgaagcg
    10561 tgcgatggtg cggcagggtg agcgcgtggc aaccagctgt gcaacggcat catcccggct
    10621 ttcgcgccaa aaccaaagaa ggccatcagg aacaccgccg acgccagccc cggagaaagt
    10681 gaaagcgtgc ggaaactggc aaaatcgagg ctgccgcttt cgcgccccat cagcaagaag
    10741 gcgatcataa tcagtaccga tccggcgtgg gcgataaaaa agtagagcat gccagcgttg
    10801 attgacgttt tatcctgcct ggcaatgacc agaaaccagg aagacagcga catcatttca
    10861 aacagcacga tgaaccaaaa agcgttgtcc atcaccagca gggcaaccat cgatgcgatg
    10921 aaaagattca taaagaagcc catcgccgcc gcgcctttgc cctcgtattc gcgcatataa
    10981 gtcaatgaat agagcgaaca aaccaccacc agcaaggaga taaccagcac cataaatgcc
    11041 gagaggctat ccattcgcag ggttaaatcg gcaaagttaa aaggcgtggc aaaacgggcg
    11101 actaaagtta cgcctgcatg taattgcgta attccgctga tgatgccaat cacgccaccc
    11161 accagcgatg tgatgccgga aagcttaata gccagtctgt ccagaccgag taaaaacagc
    11221 gaagccagac tggcaaacag atagaggatc agcgaccagg ttaataattg cagggcatcc
    11281 attagcgttg ctcctgagtg agggaaaggg gatcctcccc gccattggca aaccagcttg
    11341 cggcaaggcg ctgtttttct ttcatctgac gttgcaggct atcgtcggtg atcagccgta
    11401 acgcctgatt cgggcaagcg cgaacgcagg ccggaccttc tggcaagaaa tcacacaggt
    11461 cgcatttcac cgcgacggtc tggacacccg gttcccagcg cagcaaagca tgttgggtcg
    11521 gcgcgttttc ttcgccgtct ttgagtgagc catcagcctg aaaaacatat tgcgccgggg
    11581 cattcaccgg acggcttcct gaagcgctga ttgcaccaaa tgggcagacc acggcgcaaa
    11641 gcttgcaacc aatacaaagg ctttcgttga gttggatcgc atcatccctc tgggagatgg
    11701 cattgaccgg gcagacctgc aggcaagggg cttcctcaca gtgatgacac acgacagggg
    11761 cagtgagtgt tgacgtcttc gccagggcca ggcgcgggtg ttgctgtaaa ccttgcgttt
    11821 tatgcacgtc cgaacaggca gcgagacagg tattacatcc tgtacaccac agtggttcgg
    11881 ccaccacaaa gcggttcatg tcggctcctt gaaaatgata tgaaacattg catttcatat
    11941 tgcataaagg atgccagtct gattaattta atgtattcaa taagttatga attaactgta
    12001 ttctgaacgg tacaaaaatg atggtcatta acgttcagca aaaaatgaat tcgacacccg
    12061 tgtcgcaggg gaaagcgaga atgtgatctt gatcacgaga agtgaggtgt gctgaccgca
    12121 agcgcagcca gcacggaatg gagcaaagta atcaggcgtg ttctttcagc cagttcagca
    12181 caacgtcgtg gtgattgctg gttttgaaat cgtcaaagac atgttcgatt ttgccatcag
    12241 cgtcaatcag gaagctgatg cgatgaatac catcgtaggt tttgcccatg aaggactttt
    12301 caccccagac gccgaattgt tcgcacacct ggtggtcctc atcagacagg agcgtaaagt
    12361 taagcagctc tttttccgca aaacgggaga gtttttcggg tttatcggtg ctgataccca
    12421 gcacatcaac gcccgctttt ttcaactcat ccatgttatc gcgtaagccg caggcctgta
    12481 cggtacagcc gggggtcatg gctttcgggt agaaataaac cagaacacgc tgtccctgga
    12541 agtcggtcaa attaacttgt tctccgtctt gatccggcaa gctaaatttc ggtgcgatat
    12601 caccggcttt cagtggattc attacttaac tccatcctgt tcatcatgtt gggaataatt
    12661 gacgacgtta atactgcctt gtgcattgag ttctgtacat agggctttga acgcttgctc
    12721 aatatttgct gcgtccgcag atgcggggct gtgggcggtt atctgaatat gcaactgcgc
    12781 agcccgttca ttttcagcag gttgcgtgcg tgacaccagc tccgcaatgt tcatatgatg
    12841 cgcgtcgaaa agtgctgtga agcgttcaat taaatgcggg gagtctgcca catcgacctg
    12901 aacccagaca gatgctggca ttggcggacg cggacgcgcc gtcgtgcgct tcatcacgat
    12961 taaaagatcc agttctgcac ctttcaacgg taacgttgat tcaatcagag taatggcatt
    13021 ccatgaaccg gaaagcagca tgataaacgt gaactcttct cccagcatcg ccaggcgact
    13081 gtcttcaata ttacagccgc aactactgac atgacgggtg atggtgttca caattccagg
    13141 gcgatcggca cccaacgcag tgatcaccag ataatgttgc gatgacagtg tcaaactggt
    13201 tattccttta aggggtgagt tgttcttaag gaaagcataa aaaaaacatg catacaacaa
    13261 tcagaacggt tctgtctgct tgcttttaat gccataccaa acgtaccatt gagacacttg
    13321 tttgcacaga ggatggccca tgttcacggg aagtattgtc gcgattgtta ctccgatgga
    13381 tgaaaaaggt aatgtctgtc gggctagctt gaaaaaactg attgattatc atgtcgccag
    13441 cggtacttcg gcgatcgttt ctgttggcac cactggcgag tccgctacct taaatcatga
    13501 cgaacatgct gatgtggtga tgatgacgct ggagctggct gacgggcgca ttccggtgat
    13561 tgccgggacc ggcgctaacg ctactgcgga agccattagc ctgacgcagc gcttcaatga
    13621 cagtggtatc gtcggctgcc tgacggtaac cccttactac aatcgtccgt cgcaagaagg
    13681 tttgtatcag catttcaaag ccatcgctga acatactgac ctgccgcaaa ttctgtataa
    13741 tgtgccgtcc cgtactggct gcgatctgct cccggaaacg gtgggccgtc tggcgaaagt
    13801 aaaaaatatt atcggaatca aagaggcaac agggaactta acgcgtgtaa accagatcaa
    13861 agagctggtt tcagatgatt ttgttctgct gagcggcgat gatgcgagcg cgctggactt
    13921 catgcaatta ggcggtcatg gggttatttc cgttacggct aacgtcgcag cgcatgatat
    13981 ggcccagatg tgcaaactgg cagcagaagg gcattttgcc gaggcacgcg ttattaatca
    14041 gcgtctgatg ccattacaca acaaactatt tgtcgaaccc aatccaatcc cggtgaaatg
    14101 ggcatgtaag gaactgggtc ttgtggcgac cgatacgctg cgcctgccaa tgacacctat
    14161 caccgacagt ggtcgtgaga cggtcagagc ggcgcttaag catgccggtt tgctgtaaag
    14221 tttagggaga tttgatggct tactctgttc aaaagtcgcg cctggcaaag gttgcgggtg
    14281 tttcgcttgt tttattactc gctgcctgta gttctgactc acgctataag cgtcaggtca
    14341 gtggtgatga agcctacctg gaagcggcac cgcttgcgga gcttcatgcc ccggctggaa
    14401 tgattttgcc ggtgacctcc ggtgattatg caatcccggt gaccaacggt agtggtgctg
    14461 tcggtaaggc gctggacatt cgtccaccag cccagccgct ggcactggtt tctggcgcgc
    14521 gtacccagtt cacgggcgat accgcttcat tgctggtgga aaatggtcgt ggcaatactc
    14581 tgtggccgca ggtggttagc gtgctgcagg cgaaaaacta caccatcacc caacgtgatg
    14641 atgctggtca gacactgacc accgattggg tacaatggaa ccgtctggac gaagacgagc
    14701 agtatcgtgg tcgttatcaa atctctgtta agccgcaggg ttatcagcag gcggttacgg
    14761 ttaaactgct gaacctggaa caggcgggca aaccggttgc agacgcggct tccatgcagc
    14821 gttacagcac ggagatgatg aacgttattt ccgccggtct ggataaatct gccactgacg
    14881 ccgcgaacgc tgcgcaaaat cgtgcctcca ccactatgga cgtacaaagt gcagctgatg
    14941 acaccggttt accgatgctg gtcgtacgcg ggccgttcaa tgtggtttgg caacgtctgc
    15001 cagcggcgct ggaaaaagtg ggcatgaaag tgaccgacag cacccgttcg cagggtaaca
    15061 tggccgtaac ttacaagccg ctgtctgaca gcgactggca ggaactgggc gcgagcgatc
    15121 caggcctggc atccggtgac tataaactgc aggttggcga tttagataac cgcagcagcc
    15181 tacagttcat cgatccgaaa ggtcatactc tgactcagag tcagaacgac gcgctggtag
    15241 ctgtcttcca ggctgcgttt agcaagtaaa aatacagggc tggagtcatc cggccctttt
    15301 ttctgatatg atacgcaaac gtgtgcgtcg gcagaaaaat gcgattttag cggtaattcg
    15361 cacaaaattt gtttgtcgga cgtaggtcgg ataaggcgtt cttgccgcat ctgacaaaac
    15421 atccggcaca ccagacagca aaagatttta aaacgttaat tcacacccag gagtgataaa
    15481 gatgcaaaag caagctgagt tgtatcgtgg taaagcgaaa accgtataca gcacggaaaa
    15541 cccggacctg ttggtgctcg aattccgcaa tgatacgtca gcaggggatg gcgcgcgcat
    15601 tgagcagttt gatcgcaaag gtatggtgaa caacaagttc aactacttca ttatgagcaa
    15661 actggctgaa gcgggtatcc cgactcaaat ggagcgtctg ctctccgaca ccgaatgtct
    15721 ggtgaaaaag ctggatatgg tgccggttga gtgtgtcgtg cgtaaccgtg ctgctggctc
    15781 tctggtgaaa cgacttggaa tcgaagaagg tattgagctg aacccgccgc tgttcgatct
    15841 gttcctgaaa aacgacgcca tgcacgatcc gatggtcaac gaatcttact gcgaaacctt
    15901 tggctgggta agtaaagaga acctggcgcg tatgaaagag ctgacctaca aagcgaacga
    15961 cgtgctgaaa aaactgttcg atgatgctgg tctgattttg gtcgacttta aactggagtt
    16021 tggcctgtac aaaggtgaag tggtactggg cgatgagttc tccccggacg gcagccgcct
    16081 gtgggacaaa gaaacgctgg agaaaatgga caaggaccgt ttccgccaga gcctcggtgg
    16141 cctgatcgag gcctatgaag ccgtcgcccg ccgcctgggt gtacagctgg actgattttt
    16201 ctgctcatca tcttgccgtg cagctggcac ggcaagacaa ccgctctcat aagatgtgca
    16261 ttgaacgctc attcctccgc catttcatcc cgctttactg tggtaatctt cctctgaacc
    16321 acctacgatc atttctataa tgaatatatt gttgaggtat ctatgcgttg gcaagggcga
    16381 cgtgaaagtg acaatgttga agacaggcgc aacagctctg gtggtccgtc tatgggcggt
    16441 cccggttttc gcctgccaag cggtaaaggc gggctgattt tactgattgt cgtgctggtt
    16501 gcaggctact atggcgttga tttaaccggg ttgatgaccg gacagccggt ttctcaacag
    16561 caatcaacgc ggtcaattag cccaaatgaa gacgaagccg caaaattcac ctcggtgatt
    16621 ctggcaacca cggaagacac ctggggacag cagttcgaga agatgggtaa gacctatcag
    16681 caaccgaagc tggtcatgta ccgtggaatg acgcgcaccg gatgcggggc gggccagtcc
    16741 attatgggac cgttctattg cccggcggat ggcacggttt atatcgatct ctccttctat
    16801 gatgacatga aagacaaact tggcgcggat ggcgattttg cccaggggta cgttatcgcc
    16861 catgaagtcg gtcatcatgt gcagaaactg ttaggcatcg agccgaaagt tcgtcaactg
    16921 caacaaaacg cgacgcaggc ggaagtgaac cgcttatctg tgcgtatgga actccaggcc
    16981 gactgttttg ccggtgtctg ggggcatagt atgcagcagc aaggtgttct ggaaaccggc
    17041 gatctggaag aggcgctgaa cgcggcgcag gccatcggcg atgaccgttt acaacagcaa
    17101 agtcaggggc gagtagtacc agacagtttc actcatggca cttctcagca acgctacagc
    17161 tggtttaaac gtggtttcga cagcggtgat ccggcacaat gcaatacttt tggtaaaagc
    17221 atttaacttc cggggcaggg atggctgaac tgactgcgct tcacacatta acagcgcaaa
    17281 tgaaacgtga agggatccgc cgcttgctgg tgttgagcgg ggaagagggt tggtgttttg
    17341 atcatgcgct taagttgcgt gatgccttac ctggcgactg gctgtggatt tcgccgcagc
    17401 cagtcgctga aaaccactgt tttccctcgg cgctacaaac tttacttggg cgcgaattcc
    17461 ggcatgcggt attcgacgcc cgccacggct ttgatgccgc tgcctttgca gcacttagcg
    17521 gaacgttgaa agcgggaagc tggctggtgt tgttactccc tgtatgggaa gagtgggaaa
    17581 accaacctga tgccgactcg ctgcgctgga gtgattgccc tgaccctatt gcgacgccgc
    17641 attttgtcca gcatctcaaa cgtgtactta cggcgaataa cgacgccatc ctctggcggc
    17701 aaaaccagcc gttcacgttg gtgcattttg ctccccgtac tgactggcac cccgcgaccg
    17761 gcacaccaca accagaacaa cagcaactct tacagcagtt actgaccatg ccgccgggcg
    17821 tggcagcggt aacggctgcg cgtgggcgcg gtaaatcggc gttggcaggg caactcattt
    17881 ctcgtattgc gggcagtgcg attgtcaccg cgcccgcaaa agcggcaacg gatgtactgg
    17941 cacaatttgc gggcgagaag tttcgcttta ttgcaccgga tgccttgtta gccagcgatg
    18001 agcaagccga ctggctggtg gtcgatgaag ccgcagccat acctgcgccg ttgttgcatc
    18061 aactggtatc gcgttttcct cgaacgttgt taaccactac ggtgcagggc tatgaaggca
    18121 ccggacgtgg ttttttgctg aaattttgcg ctcgctttcc acatttacac cgttttgaac
    18181 tgcaacaacc gatccgctgg gcgcagggat gcccgctgga aaaaatggtt agtgaggcac
    18241 tggtttttga cgacgaaaac ttcactcacg aaccacaagg tgacatcgtc atttctgctt
    18301 ttgaacagac gttatggcga agcgaaccag aaacgccgtt aaaggtatat cagctattgt
    18361 ctggcgcgca ctaccggact tcgccgctgg atttacgccg catgatggat gcaccagggc
    18421 aacatttttt acaggcggct ggcgaaaacg agattgccgg agcgctgtgg ctggtggatg
    18481 agggcggatt atctcaagaa ctcagtcagg cggtatgggc gggttttcgt cgcccgcggg
    18541 gtaatctggt ggcccagtcg ctggcggcgc acggcagcaa tccactggcg gcgacattgc
    18601 gcggacggcg ggttagccgg atagcagttc atccggctcg tcagcgggaa ggcacagggc
    18661 ggcaacttat tgctggtgct ttgcaatata cgcaggacct cgactatctt tcggtgagtt
    18721 ttggttacac cggggaatta tggcgtttct ggcaacgctg cggttttgtg ctggtgcgaa
    18781 tgggtaatca tcgtgaagcc agcagcggtt gctatacggc gatggcgctg ttaccgatga
    18841 gtgatgcggg taaacaactg gctgaaggtg agcattaccg tttacgtcgc gatgcgcaag
    18901 ctctcgcaaa gtggaatggc gaaacgcttc ctgttgatcc actaaacgat gccgtccttt
    18961 ctgacgacga ctggcttgaa ctggccggtt ttgctttcgc tcatcgtccg ctattaacat
    19021 cgttaggttg cttattgcgt ctgctacaaa ccagtgaact ggcattaccg gcgctgcgtg
    19081 ggcgtttaca gaaaaacgtc agtgacgcgc agttatgtac cacacttaaa ctttcaggcc
    19141 gtaagctgtt actggtccgt caacgcgaag aagccgcgca ggcgctatac gcacttgatg
    19201 atgttcgcac tgagcgtctg cgcgatcgca taacgcaatg gcaatttttt cactgactcc
    19261 ttcaattttc tcccatggtc attgtgagtc agcggcgtaa aattaatgac atcagttaag
    19321 gagttcgcca tgaaacatga ccattttgtt gttcaaagcc cggataaacc tgcgcaacag
    19381 ttgttactgc ttttccacgg tgtcggggat aacccggtgg caatggggga aataggtagc
    19441 tggtttgcac cgctgtttcc tgatgcgctg gtggtgagtg tcggtggcgc ggagccgagc
    19501 ggtaatccgg cggggcgtca gtggttttcg gtgcagggta ttacggaaga taatcgccag
    19561 gagcgtgtgg atgccatcat gtcgacgttt attgaaacgg tacgctactg gcagaaacaa
    19621 agcggagtag gggctaacgc cacggcgcta atcggtttct cacaaggcgc gattatggcg
    19681 ctggagagca ttaaagccga accgggcctt gcttcgcgcg tcattgcctt caacggacgc
    19741 tacgcgagcc tgccggaaac cgcgtctaca gccacgacaa ttcacttgat tcatggcggt
    19801 gaagatccgg ttatcgatct ggcgcatgcg gttgcggcgc aggaagcgtt aatcagtgcc
    19861 ggtggtgacg tgacgctgga tatcgtggag gatttaggcc atgcgatcga caatcgcagt
    19921 atgcaatttg ccctggatca cttgcgttat accattccga aacattattt cgacgaagcg
    19981 ctaagcggcg gtaagcctgg cgatgatgat gtgattgaaa tgatgtaata atagccgggt
    20041 aggcctgata agactgtatc aggcatcatg gccggatgtg gcgtgaacgc cttatccggc
    20101 cgctcagctt acttcttcgg ttgatccttt ttcggccagt cgtcgtcatc gtcccactta
    20161 tcgttgaaat cacgatgcgg gggaagctcc ggcttgttgg cgagaaattt cttatggtcg
    20221 acgcgcttga gatctttaat cacgttcagc aggacgccta ccaaaaagac aatcaccaga
    20281 atccaccaat atttagccag ccagtccatg cttatttcct cttgcagaac cactcatcag
    20341 gcgacgagct gttccatgat acgttgatac atacgggcaa gtagctgcag gtcggcagcg
    20401 ttcacacatt cattaatttt atgaatagtg gcattgaccg gcccgagttc caccacctgc
    20461 gcccccatgc gggcaataaa gcgcccgtcg gacgttccgc ctgtggtcag tagctgcggt
    20521 ttaatttcat tatagtgctc aaccgcgtta acgaccgcat ccaccagttt accgcgcgcg
    20581 gtcaaaaatg gctgcccgga aagccaccaa tccaccgtat agcgcagttg atgtttttca
    20641 agcagggcaa gtacctgcgc tttgatcatc tcatcagtca gttcggtgct gaagcggaag
    20701 ttaaactgca caaacagttc acccggaata acgttgttac tgcccgttcc cgcctgaata
    20761 ttggcaatct gcatactggt cgccgggaag aattcattgc cctgatccca ctcaatagcc
    20821 actaattcat taaggaaagg tgctgcgcga tgtaccggat tgtcagccag atgtgggtag
    20881 gcaacatgcc cctgcacgcc atgaatggtg aggttgcagg ttaacgatcc gcgacgacca
    20941 tttttcacca catcaccaac cacttcgata ctcgacggtt cgccgaccag gcagtaatcg
    21001 agacgctcat tacgcgccat taacgcttcg acgactttta ccgtaccgtt atgggcactg
    21061 gcttcttcat cagaagtgat cagaaatgcc agtcgccccg tatggttggg atgttgtgcg
    21121 acaaagcgtt ctgccgctac caccatcgcc gccagcgagc ctttcatatc tgccgcaccg
    21181 cgcccgaata acatgccgtc acgaatggtg ggttcaaacg gcggattgat ccaacgatcg
    21241 gcgtcgccag gcggcaccac gtcggtatgc ccggcaaagg ccaacgtttc accttgccca
    21301 cgccatgccc aaaaattctg cgtatcggca aagtccatgc gttcaacggt aaaaccgatc
    21361 gcctgcaaac gttcaatcaa caaagcctgg catcctgcat catcaggact cagggaaggg
    21421 cggcgaataa gctgttgtgt cagctcaata accgggcacg acatagacta cacctcatgg
    21481 aaaaattgct gataactgga atcactgaaa cccagcagca taggcttacc aggcgcgcag
    21541 agcaatggac gtttgataat tgcaggcatt tcagtcatta atgccgccgc agaggccgca
    21601 tcgatgattt tattgcgggt ggtttcgtcc agtttacgcc aggttgtacc acgggtgttg
    21661 agtaacgctt cccagcctaa ttcgttgata aaaccgttca ataattcgct gtccagccca
    21721 tcgacgcggt aatcatgaaa acgatagtcg atgttattgg cttccagcca acggcgagcc
    21781 tttttaatgg tgtcacaatt tttgatgccg taaagtgtaa ccataatgaa tcctttttcg
    21841 atttatgaga ataaatactc atttaagggt gaaaacattt tgcctgcaaa tgattatcag
    21901 gaaatataac attatcgaag tattcaaatt aacaactatt aaataatatt aaacattttt
    21961 aacgtaaaca ttaagaatat tcatcttgtt atctgcctgt attttaacca gaattaaatc
    22021 agtattagat gccgtatgaa tatctcgaaa tgttgctgtg tatcacatac aaatcatcac
    22081 cgcaggacca tagtatttac ataaggtttg tcccccggag gtagtcatcg cagcaatcga
    22141 gtaaattagc ttcaccacgg tatattgttt ccgtagaata cccataatta taagagaggt
    22201 tgttatgatt gaacgtgaac tggggaactg gaaagacttt atcgaagtta tgcttcgtaa
    22261 gtaattcctg agacaaagta caaacagcaa gaacccgctg agcaggttct taatcggaaa
    22321 gttgaaaaag gcgacacatt ggcatgtcgc cttttttatt gcttattccg ggcgcggctt
    22381 tagcgggaag cggcggcgca ccagcacaaa gaacagcggc acgaagtaaa tagccagaat
    22441 agtggccgaa atcatcccgc ccattacgcc agtacccacc gcatgctgac caccggaacc
    22501 ggcacccgtg ctggttgcca ttggcaatac gccgaagata aatgccagcg aggtcatcag
    22561 aattgggcgt aaacgctgac ggcaggcgtg gagcgtcgct tcaaacaggt cgtggccttt
    22621 ttggttcatc tcgttagcaa actcgacgat caggatggcg tttttcgccg ataaaccaat
    22681 gaccgttaac aggcccacct ggaagtaaac gtcgttttcc agcccgcgca tccaggttgc
    22741 cagcagcgcg ccgataaccc ccagcggcac gaccagcatt accgagaacg gcaccgacca
    22801 gctttcatac agcgccgcca gacacaggaa taccaccagc aaggaaatag cgtacagcgc
    22861 cggagcctgc gcgccggaaa gccgctcctg atacgacatc gccgtccact ccagaccaaa
    22921 gccgtttggc agctgcttca ctaacgattc cataatatcc atcgccgtac cggtactgac
    22981 ccccggtgcg gcttccccaa caatctcaac cgcagaataa ccgttatagc gttccagacg
    23041 cggcgagcct gtctcccagc gtgaggtcgc gaaagcagag aagggcacca tgccgccatc
    23101 tttatttcgg acataccaga gattgatgtc atctggcagc atgcgatacg gcgcagctgc
    23161 ctgcacatag actttcttca cgcgaccgcg atccataaag tcattcacat agctcgaacc
    23221 ccaggcggtt tgcagtgtgt cgttaatatc gtcgatagca acgcccagcg cctgagcttt
    23281 acgctggtcg atatcaatct gcaactgcgg actgtcgtcg aggccgttat ggcgcacacg
    23341 ggttagctcc gggttttccg ctgccagcgc cagcaactgg tttcgtgctg tcatcagcgc
    23401 atcgtgaccc gctccagcgt ggtcctgcaa ctccatatca aaacccgcag aactaccaag
    23461 accgctaatt gctggcgggc tgctggcgat aacgcgagct tctttaatct tgttaaacgc
    23521 cttcgttgca cgctcgataa tggcaaacga ggtgccggtc ttactgtcgc gttcgctcca
    23581 gtctttcagg cggataaaca ttctcgccac gttttgcccg ttacccccag ggccagaacc
    23641 aacggtggca aacaccgaca tgatgttgtc tttttcatgg gtgaagtagt atttctcgat
    23701 ttgctcaacg actttcaggg tctgttgttg ggttgaaccg ctgggcaact gtaccgaggt
    23761 agtaaacatg ccccggtctt ccagtggcaa gaacgacgtc ggcaaacgca ggaacaggaa
    23821 caccatgccg ccaagcagca ggacataaat cacaatccag cgcaggctac ggtggagaat
    23881 tttcgccacc cctttttcgt agcgttcggc gttgcggtta aacatctggt taaaccaggc
    23941 aaaaaagcct ttttgcccgt gatgctcacc ctttttcagt ggcttaagta gcgtggcaca
    24001 cagagccgga gtgaggatca tcgctaccag tactgacagc accatcgccg caacaatggt
    24061 aatagagaac tggcgataga tggcaccggt ggtgccgccg aagaaggcca ttggtacaaa
    24121 taccgccgaa agcaccatcg caatcccgac cagtgccccc tggatctgcc ccatcgattt
    24181 acgtgtggct tcgcgaggag tgagtccttc ctcactcata atacgttcga cgttttccac
    24241 caccacgatg gcgtcatcca ccagcagacc gatcgccagc accattgcga acatggttaa
    24301 ggtgttgacg ctgtaaccga aggcgtaaag tacggagaag gttcccatca acaccaccgg
    24361 cacggcgata gtgggtatca gcgtggcgcg gaagttttgc aggaacagat acataacgag
    24421 gaaaaccaga gcgatagctt ccagcagcgt tttcaccacg tcttcaatgg aggctttaac
    24481 aaacgaggtg gtttcatacg ccaccttgta ttccagtccg tgcgggaaat actgcgccag
    24541 ctcgtcgaga cgattgagca ccagctccgc tgtcgccatt tcgttcgcgc cggaggccag
    24601 ttttaccccc aacccggagg ctggcttacc attgaagcgg ctaagataat cgtatttctc
    24661 cgcccccatt tcgacggtgg cgacatcgcc cagccttacc tctgagccgt cctgattcac
    24721 ccgcaaggtg atatcgcgga actgttctgg tgtttgcagc agtgactggg cgttaatggt
    24781 ggcgttgagc gcctgcttat cgacggaagg cgtaccacca agttgcccaa ccgcaatctg
    24841 cgcgttctgt gactcaatgg catcagtgac atctttagcc gtcatctgga aactgttgag
    24901 tttcgccggg tccagccaga tacgcatgga atattgcgaa ccataggcat cgatatcccc
    24961 gacgccattc acgcggctta acggatcctg aatattactg gcaacgtaat cggcaatatc
    25021 ctgtttatcc atcgaaccat cggtagagac gaaggcaatg gtcagaatgt tggtatcgcc
    25081 ggttttacgc accgtcacgc cctgattttg caccgcctgc ggtaactttc gcatggctga
    25141 ttgcagctgg ttttgtactt gctgcacggc ttcgtccgga tcggtgcctg ctttaaaact
    25201 taaagtgaca gatgcctggc cggtgccact gctctgagac gacatataca tcagattatc
    25261 gagaccggtc atattttgct cgataacctg ggtcacggtg ttttccagcg tctgggccga
    25321 tgcgccggga tagttagcgg tcactcgcac attcggtggc gcgagatcgg ggtattgttc
    25381 aacgggcaat gagaaaatcg ccagggtccc tgtcagacac aacaggattg ccagcaccca
    25441 ggcaaaaatg gggcgatcaa taaagaaatt cgccattaaa agaggacctc gtgtttctgc
    25501 gtatcgttgt aggcttgact tgcttcactg tagcggcaag gtacgagcca atcgtggaga
    25561 aaaaaaggag ttaatgtaaa ttatcatgcc cttttatact gaaccttaag tgccactatt
    25621 ctttggtcaa taagaggcat tacatcagct gactttcctc accctccgca gagcgaaagc
    25681 taatactcac taacgtgccg ccgccggaag gttgcgaaaa agtcagcgtc ccacccaatc
    25741 tttccgcgcg ttcgcgcatg atattcagac cataatggcc ttcgggttct ttcggttcac
    25801 cgatgccaat cccgttgtcg cgaatataga ccgtgtgatt gccatccggc gcggtgacgc
    25861 agctaacggc gatttcgctg gcgttggcgt gcttcatcgc attcagcacc gcttcgcgaa
    25921 taatttgcaa caaatgcacc tgcatttgcg catccagcgc cagggttggc aggcggcagt
    25981 cgagggtcag tttagcgctg gtttgatttt gtaacgtatc cagcatttcc ctcaacgcgg
    26041 aggggagatc tgcctgctgc agcgtcaggc ggaaagtagt caacagctcg cgtaactgcc
    26101 gataagcatc attcaacgcc tgggaaaaat cggccatgat actttgtgcg gtggcgttat
    26161 cttccggtat cgaacgcttc agtaacgtca actggatacg taagtaagaa agtacctgag
    26221 ccagcgagtc gtgcaattcg cgggcgatgg tcgcacgttc ttccatcaac aataactgct
    26281 gaaaatgctt ctgcgcctga ttaaagtaca aaccgcgtcc cagcatcgac gaaacgctgt
    26341 taagcagcgg ttctgatgat gaaacgtgac tattttgcca gtgcagttcg ccgtaaaccg
    26401 tctcttgcat tgtcactggt aaaatctgca tcggcaattc cgggtttggt tgcccttcgc
    26461 taatccgcca gttttcaccg acatttaact ccagatattc agccgcttcg ttgtcgcgca
    26521 caatctgcaa aatatggcgg aaacaatgca catcaatctg gctggtgttc agcgcctgcg
    26581 aacactgata caacacctcc aggcgacgct tggcctcgtg gaggtcgcgg gtcttttctt
    26641 ctactgacgc ctccagcgaa cggtacaatt tatgtagctc gctcgacatc tggttaaagg
    26701 ttttggcaag caggccaagc tcattcggca ggctggtatc cagcggcggc gagtcgaact
    26761 gtccgtgttc aatacgctga ctggcggtaa ccagctgatt cagcggggca accacctgat
    26821 ggcgtatgcg gcgcaaagta aaaaagacca gcgtgaaaat accgatgccg ccagccaggg
    26881 aaatcgccac caccagcagc attttgcgtt cagcgtagtg ctgtaaagcc agcacgaaca
    26941 ggtctatttg attaacataa ttattaatat tggcctgata ccacggcaag tcgcccttgc
    27001 tgagccgatt attcatctcc agccagttgg cattcagatg cgcgtagcgg gtttttactg
    27061 cctctggcac ataccagacg ttgagattgg ttaataccgg tgaatgcagt gcctgctgaa
    27121 acaactggcg atgtgcattg agttgtggac tgccactttg caagtcgtag cccaggcggt
    27181 aactctgcat acgcagcgat ccggcaatat tgatagcctc agcgtcgcgt aaactgctcg
    27241 ccagcgttag cagagcgata cccgtggaaa gaatcgacag cagcacaatg taaaaaaagg
    27301 cccgggccag actggccgag acgggtcgtt taacaatcac acgcgtcttc tccacaaaaa
    27361 atcattaatg ttccagttcg ctgaaacgca atttagtcag tgatgggatt atttgatctg
    27421 ccacagttta tagcgaaata gttacttatt ctgggcacat gaacattgcc gattcccctg
    27481 taagtcgggt aataacaaca ctcatataaa gcataaggtt tttacaacca aaaaagaagg
    27541 tcgttatgaa tcgttttatt atggccaaca gtcagcaatg tctgggttgt catgcttgtg
    27601 aaatcgcctg tgtcatggct cacaatgatg agcaacatgt cctgagccaa caccattttc
    27661 atccccgaat tacggttatc aaacatcagc agcaacgtag tgcagtgacc tgtcaccatt
    27721 gcgaagatgc gccctgcgcc cgtagttgcc ctaatggcgc aatcagccac gttgatgaca
    27781 gcattcaggt caatcagcaa aagtgtattg gctgtaaatc ctgcgtggtg gcctgtccat
    27841 ttggtacgat gcaaatcgtc ctgacacccg tcgcggcggg caaagtaaaa gccacggcgc
    27901 ataaatgcga cctttgtgca gggcgcgaaa acggtcctgc ctgtgtcgag aattgcccgg
    27961 cggacgcgct gcaactggtc actgatgccg cactctccgg catggcgaaa tcccgccgcc
    28021 tgcgcaccgc acgtcaggaa catcaaccgt ggcatgccag taccgcggca caagaaatgc
    28081 cggtaatgag taaagtcgag caaatgcagg caacgcccgc gcgtggcgag ccggataaac
    28141 tggcgattga agcgcgcaaa accggttttg atgaaattta tctgccattc cgtgtcgatc
    28201 aggcacaacg ggaagcctcg cgctgcctta aatgcggcga gcacagcgtt tgtgaatgga
    28261 cctgcccgct gcataaccat attccgcagt ggattgaact ggtgaaagcc ggaaacatcg
    28321 acgccgccgt cgagctttct caccagacca acaccctgcc ggaaattacc ggacgcgttt
    28381 gtccgcaaga ccgtttgtgt gaaggtgcct gtactattcg cgatgagcac ggcgcagtaa
    28441 ctatcggcaa cattgaacgc tacatttcag atcaggcgtt ggcgaaaggt tggcgtcctg
    28501 acttaagcca tgtcaccaaa gtggacaagc gggtggcgat tatcggtgcg ggtccggcag
    28561 ggctggcctg tgcggatgtt ctgacccgca atggcgtaga ggtgacggtg tacgatcgcc
    28621 atccagaaat cggtggcttg ctcactttcg gcattccttc tttcaaactg gataaatccc
    28681 tgctggcacg ccgtcgggaa atcttcagcg cgatggggat tcacttcgaa ctcaattgtg
    28741 aagtgggtaa agatgtctct ttggattcgc ttttggaaca atacgacgcg gtcttcgttg
    28801 gcgtaggcac ttaccgttcc atgaaagcgg gtttacccaa tgaagatgcg ccgggcgttt
    28861 atgacgcgct gccgttcctc attgccaaca ctaaacaggt gatgggactc gaagagctac
    28921 cggaagagcc gtttatcaat accgccggac tcaacgtcgt ggtactgggc ggcggcgaca
    28981 ccgcgatgga ctgtgtgcgt actgcgctgc gccacggcgc gagtaacgtc acctgcgctt
    29041 atcgtcgtga tgaagctaac atgccaggct cgaagaaaga ggtgaagaac gcccgcgaag
    29101 agggggccaa cttcgaattt aacgtccagc cggtggcgct tgagctgaat gaacaaggtc
    29161 acgtttgcgg gattcgtttc ctgcgtacgc gtcttggcga gccggatgcc caggggcgtc
    29221 ggcgtccagt accggtggaa ggcagtgaat ttgtcatgcc agccgacgcg gtgattatgg
    29281 cgtttggctt caatccgcac gggatgccgt ggctggagtc gcacggtgta atggtagaca
    29341 aatggggccg catcatcgcg gatgtggaaa gccagtaccg ttaccagacc accaatccga
    29401 aaatcttcgc tggtggtgac gccgtgcgtg gtgcggatct ggtggttacc gcaatggcag
    29461 aaggacgtca tgcggcacag gggattattg actggctggg ggtaaaatca gtcaaatctc
    29521 actgatagcc tgcgcagaca aacccgactt cacagcgtaa gataattgtt catttcgcgc
    29581 tgtggagtcg gtatgacgca acaaatcacc ctcattaaag acaaaattct ctccgataac
    29641 tatttcaccc tgcacaacat tacctacgat ctcacgcgca aagatggcga agttatccgc
    29701 cataaacgtg aagtttacga tcgcggtaat ggtgcgacga tcctcctgta caacgcgaag
    29761 aaaaagaccg tggttctgat tcgtcagttc cgcgtcgcta cctgggttaa tggcaatgaa
    29821 agcgggcagc tgattgaaac ctgcgccggg ctgctggata acgacgaacc ggaagtgtgt
    29881 attcgtaaag aagcgattga agagacgggt tatgaagtgg gcgaagtgcg caaattattt
    29941 gaactgtata tgtcgccagg cggtgtgact gagctaatcc acttctttat cgccgaatac
    30001 agtgacagcc agcgcgctaa cgccggtggt ggtgtcgaag atgaagatat tgaagtgctc
    30061 gagctgccgt tcaacaaggc gctggagatg atcaaaactg gcgagatacg tgacggtaag
    30121 acggtgttat tgcttaacta tttgcaaatg tcacatttaa tggactgaaa aataacaata
    30181 atatttcgtt gtttattatt ggctcaatcc gataaatccg attgagccgc gctacctgcg
    30241 caacgaagat acgacttgtg ctgtttgttt gaacttctgg ggtcgtaccg tccatgcgct
    30301 atcgcatttt ccttctcttt tttttcgctt tgttgccgac gtctttggtg tgggcggcac
    30361 cagcgcaacg ggcgttttcc gactggcagg tcacctgtaa taaccaaaac ttctgcgtgg
    30421 cgcgtaatac gggcgatcat aacggactgg tgatgaccct gagccgcagc gccggggcgc
    30481 atacggatgc cgttttacgt attgagcgcg gcgggttgaa gtcgccggat gcgtctgaag
    30541 gggagatagc gccacggctg ctgttagatg gcgagccgtt ggcgttaagt ggtgacaagt
    30601 ggcggatttc accatggtta ttagtaaccg atgatacggc aaccatcacc gcgtttttgc
    30661 agatgattca ggaagggaag gcgatcacct tacgcgacgg caatcagacc atttctctga
    30721 gtggcttaaa agcggcgttg ttgtttatag atgctcagca aaagcgcgtt ggcagtgaaa
    30781 ccgcgtggat aaagaaaggg gatgaaccgc cgctcagcgt accgcccgcg cctgcgctga
    30841 aagaggtcgc ggtggttaac ccaacgccga cgccactctc actcgaagaa cgcaacgatt
    30901 tgctggatta tggaaactgg cggatgaatg gtctgcgctg ctcgcttgat ccgttacgtc
    30961 gtgaggtgaa tgtcactgcg ctgaccgatg ataaagcgct gatgatgatt agctgtgagg
    31021 caggggccta taacaccatt gatttggctt ggattgtgtc gcgtaaaaag ccactggcct
    31081 cgcgcccggt tcggttacgt ttgccgttca acagcggtca ggagacgaat gaactggaac
    31141 tgatgaacgc aacattcgat gaaaaatcgc gtgaactggt gaccttagca aaagggcgcg
    31201 gattaagcga ttgtggcatt caggcgcgct ggcgctttga cggtcagcgt tttcgcctgg
    31261 tgcgttatgc cgcagaaccc acctgcgata actggcatgg gccagacgcc tggcccacgt
    31321 tgtggatcac ccgttaaaca aaatcccaga tgcgccccta aaaagcgcac ggactgtccc
    31381 ctcgcccctc tggggagagg gttagggtga ggggaacata cagcatccgg cgatcaccat
    31441 caggcacctt tcactcccag caccttatgc gcttttgcca caatattctc ggcggtaaag
    31501 ccaaagaacg ggaacagctt atctgccgga gcagattccc catagccggt catcccgaca
    31561 attgcccctt tcagaccaac atatttgtac cagtaatcgg cgatgcctgc ttccaccgcc
    31621 acgcgagccg caacgttaga aggcaacacc gactcgcgat attcctcatc ctgggcgtcg
    31681 aaaatatcgg tcgagggcag ggaaactacg cgtacattgc gaccttctcc cgctaatttc
    31741 tctgccgctt gcagggtgat ttccatctct gaaccggtgg caatcaaaat aatatctggc
    31801 ttaccgccgc tgtctttcag tacataaccg ccacgagcaa tctctttaac ctgatccggc
    31861 gtacgttcca cctgggccag attctgcctg gagaggatca gtgccgtcgg tccgttgtgg
    31921 cgctcaacgg ccagcttcca gcccaccgct gcttccacct gatcgcacgg tcgccaggtg
    31981 ctgaaatttg gcgttaagcg cagactggcc agttgctcaa cagcctggtg cgtaggacca
    32041 tcttcgccca gaccaattga gtcgtgggta taaaccataa tctgccgcgc tttcattagt
    32101 gccgccatcc gcgcggcgtt acgggcgtat tcaacaaaca tcaggaacgt cgcggtatac
    32161 ggcacaaagc cgccgtggtg cgcgatgccg ttggcgatag cggtcatgcc aaattcacgc
    32221 accccgtagt gaatgtagtt gcccgccgga tcttccttca gcgaaacaga acctttccag
    32281 atggtcaggt tgctgggagc cagatccgcc gaaccgccga gcaactcagg cagcatcggc
    32341 ccgtaagcgt taagcgtatt ttgcgaagcc ttacgggtag cgattttcgc cggatttgcc
    32401 tgtaattcat tgatatattt ctgagtcgtt ttctcccagt ccttcggcaa accgccgctc
    32461 atccgacggg taaactcttc tgccagttgc ggatgggcct ttttataggc ggcaaacttc
    32521 tcattccagc tctgctgcgc tttttcgcct ttttcgcggg catcccaggc gtgataaatc
    32581 tctttaggga tctcaaatgg cggatggtgc cagcccagtt tttgccgtgc cagcgccact
    32641 tcttcttccc ccagcggtgc gccgtgcgcc tcttccttac ctgctttatt cggcgaacca
    32701 aagccaatta ctgtgcggca gataatcagc gacggcttat ctttcacgct ttgcgcttca
    32761 aggatcgctt tcttcaccgc ctgcggatcg tgaccgtcga tttcatggat cacatgccag
    32821 tgataggctt caaaacgttt tgctgtatcg tcggtaaacc agccttcggt ttcaccgtcg
    32881 atggaaatac cgttgtgatc gtaaaaacca atcagcttgc ccagtcccag cgtgcccgcc
    32941 agcgaacaga cttcgtggga aataccttcc atcaggcaac cgtcgcccat aaacacatag
    33001 gtgaagtgat cgacaatttc atgatccggc tggttaaact gcgccgccag tgtacgcgct
    33061 gctatcgcca gtccgacggc gttcgccaaa ccttgtccaa gtggaccggt ggtggtttca
    33121 acacctggcg tatagccaat ctccgggtga cctggggttt ttgaatgcaa ctgacggaag
    33181 ttcttcagct cttccagcgg caggtcgtaa ccggtcagat gtagcaaact gtagagcagc
    33241 atcgacgcgt ggccgttgga aagaataaag cggtcgcgat cataccaggt tgggtcggtg
    33301 gggttatgtt taagaaaatc gttccacagc acttcggcaa tatcagccat gcccatcggc
    33361 gcgccgggat gaccagaatt ggctttttgt accgcatcca tactgagtgc gcgaatcgca
    33421 ttggcaaggt cttttcggga catataacac tccgtggctg gtttatagtt tggcggcaag
    33481 aagatcttcc agtttgcgtt gatcaacggc gaacagacga atgccttcag acagtttttc
    33541 taccgccatc gcatcctgat tgtgctccca acggaactcc gcttcgctca tgggagcggg
    33601 gcgtgggaac gtctgagaag gtgggattaa tttacgtacc actggcgaaa ctttttcctg
    33661 cagctccttc agcaaattcg gtgcgatagt cagtcgatcg cagccggtta aggcgaggat
    33721 ttgttcggtg cgacggaagc tcgcgcccat cacaatggtt tcatagtggt gttgcttata
    33781 gtagtcgtag atattgcgta ctgatttaac gcctggatct tcttccacca catacgggtc
    33841 catcggcttg cgtgcctgat accagtcata aatacgcccg acaaacggcg aaatcagaaa
    33901 aacgcctgct tctgcacagg cccgcgcctg tgcaaaagaa aacagcagcg tcaggttgca
    33961 gttaatacct tctttttcca gctcttctgc cgcgcgaatt ccttcccagg tcgaagccag
    34021 tttgatcaga atgcgtgatt tctcaacgcc ttgttgctga tacaagtcca ccagatggcg
    34081 cgccttctca atactctttt ctttatcaaa agagaggcgt gcatcaactt ctgttgacac
    34141 gcgaccgggt acgattttga gaatttcagc accgaaattg accgccagtt tgtcacacgc
    34201 tgcgaccacc tgttgttcct gggttttgcc attttttcta ccccaggcga tagcatcgtc
    34261 tattaaatgc tcatattgtg ataatccggc agccttgagt aacagcgaag gattggtggt
    34321 ggcatcctgg ggatgataat ggcgaatgga ctcaatatcg ccgctgtctg ccacgacagt
    34381 ggtgaactgt ttgatgccgt ctaactcgtt cataggaaat actccttgaa aagtaaagtg
    34441 ttagatgagt gcgttaattc acacttctga gaaatttcgc taaacgcatc aaaaaagcat
    34501 agcagacagg catggtattg ctggattaag caggtaacat cagtgttata ggattattac
    34561 caaaacatta tattaatggt gatagtttgg acttgctcaa agtctgtaga ctccggcagg
    34621 gtaataatgt gcgccacgtt gtgggcaggg gctgttgccc acacacttta tttgtgaacg
    34681 ttacgtgaaa ggaacaacca aatggatgac cagttaaaac aaagtgcact tgatttccat
    34741 gaatttccag ttccagggaa aatccaggtt tctccaacca agcctctggc aacgcagcgc
    34801 gatctggcgc tggcctactc accaggcgtt gccgcacctt gtcttgaaat cgaaaaagac
    34861 ccgttaaaag cctacaaata taccgcgcgc ggtaacctgg tagcggtgat ctctaacggt
    34921 acggcggtgc tggggttagg caacattggc gcgctggcag gcaaaccggt gatggaaggc
    34981 aagggcgttc tgtttaagaa attcgccggg attgatgtat ttgacattga agttgatgaa
    35041 ctcgacccgg acaaatttat tgaagtcgtc gccgcgcttg aaccgacctt cggcggcatc
    35101 aacctcgaag acattaaagc gccagaatgt ttctatattg aacagaaact gcgcgagcgg
    35161 atgaatattc cggtattcca cgacgatcag cacggcacgg caatcatcag cactgccgcc
    35221 atcctcaacg gtttgcgcgt ggtggagaaa aacatctctg acgtgcggat ggtggtttcc
    35281 ggcgcgggtg ccgcagcaat cgcctgtatg aacctgctgg tagcgctggg tctgcaaaaa
    35341 cataacatcg tggtttgcga ctcaaaaggc gttatctatc agggccgtga accaaacatg
    35401 gcggaaacca aagccgcata tgcggtggtg gatgacggca aacgtaccct cgatgatgtg
    35461 attgaaggcg cggatatttt cctgggatgt tccggcccga aagtgctgac ccaggaaatg
    35521 gtgaagaaaa tggcccgtgc gccaatgatc ctggcgctgg cgaacccgga accggaaatt
    35581 ctgccgccgc tggcgaaaga agtgcgtccg gatgccatca tctgtaccgg ccgttccgac
    35641 tacccgaacc aggtgaacaa cgttctttgc ttcccgttca tcttccgtgg cgcgctggac
    35701 gttggcgcaa ccgccatcaa cgaagagatg aaactggcgg cggtacgcgc gattgcagaa
    35761 ctggcccatg cggaacagag tgaagtggtg gcttcagctt atggcgatca ggatctgagc
    35821 tttggtccgg aatacatcat tccaaaaccg tttgatccgc gcttgatcgt taagatcgct
    35881 cctgcggtcg cgaaagcagc gatggagtcg ggcgttgcga cgcgtccgat tgctgatttc
    35941 gacgtctaca tcgacaagct gactgagttc gtttacaaaa ccaacctgtt tatgaagccg
    36001 attttttccc aggctcgcaa agcgccgaag cgcgtcgttc tgccggaagg tgaagaggcg
    36061 cgcgttctgc atgccactca ggaactggta acgctggggc tggcgaaacc gatccttatc
    36121 ggtcgtccga acgtgatcga aatgcgcatt cagaaactgg gcttgcagat caaagcgggt
    36181 gttgattttg agatcgtcaa taacgaatcc gatccgcgct ttaaagagta ctggactgaa
    36241 tacttccaga tcatgaagcg tcgcggtgtc actcaggagc aggcgcagcg tgcgctgatc
    36301 agtaatccga cagtgattgg cgcgatcatg gttcagcgtg gcgaagccga tgcaatgatc
    36361 tgcggtacgg tgggcgatta tcatgaacat tttagcgtgg tgaaaaatgt ctttggttat
    36421 cgcgatggcg ttcacaccgc aggtgccatg aacgcgctgc tgctgccgag tggtaacacc
    36481 tttattgccg atacatacgt taatgacgaa ccagacgcag aagagctggc ggagatcacc
    36541 ttgatggcgg cagaaactgt ccgtcgtttc ggtattgaac cgcgcgttgc tctattgtcg
    36601 cactccaact ttggttcttc tgactgcccg tcttcgagca aaatgcgtca ggcgctggaa
    36661 ctggtcaggg aacgtgcacc agaactgatg attgatggtg aaatgcacgg cgatgcagcg
    36721 ctggtggaag cgattcgcag cgaccgtatg ccggacagcc ctttgaaagg ttccgctaat
    36781 attctggtga tgccgaacat ggaagctgcc cgcattagtt acaacttatt gcgcgtttcc
    36841 agctcggaag gtgtgactgt cggcccggtg ctgatggggg tggcgaaacc ggttcacgtg
    36901 ttaacgccga tcgcatcggt acgtcgtatc gtcaacatgg tggcgctggc tgtggttgaa
    36961 gcgcaaaccc aaccgctgta attcattctt aactctcacg cttaccctga atattcaggg
    37021 taagcggttt tcctgaaata tattagtaaa gcttattact gagtttacga ataataaaaa
    37081 aagcagtata tgaaatatct cgatattatt ttatttatat tcatgcgtcg catatgaaag
    37141 tttattcata acagtaaata tctctccatt cttagtgatc tacctcacct tttaaacgcg
    37201 cttgccgaat tttgttattt actctgacga aaaattgtca cgatacacga aagtttttca
    37261 caggcggcga ctcatggata aagaacgcat cattcaggaa tttgtgcccg gtaaacaggt
    37321 cacactggcg catctcatcg cgcatcccgg cgaggaactg gcgaagaaaa tcggcgttcc
    37381 tgatgcgggc gcaatcggca ttatgacgct aactcccggc gaaacggcga tgatcgccgg
    37441 tgatttagca ctaaaagccg ccgatgtgca tatcggtttt ctcgaccgtt ttagcggcgc
    37501 gttggtgatt tatggctcgg tgggtgcagt agaagaagcg ttatcacaaa ccgtcagcgg
    37561 tttagggcgt ttattaaatt atacgctttg tgaaatgacc aaaagttaat acgaggcatt
    37621 catgaaacga attgcgtttg tgggtaccgt cggggcagga aaaacaacgt tatttaatgc
    37681 gttgcaggga gattataccc tcgccagaaa aacgcaggcc gtagaattta atgataaggg
    37741 tgatattgat acgccgggtg aatattttag ccatccccgc tggtatcacg ccttaattac
    37801 cacgctacag gatgtggaca tgctgatcta tgtccacggc gcgaatgacc cggaaagtcg
    37861 gttgcctgcc gggttgctgg atattggcgt cagcaaacgg caaatcgccg tcatcagtaa
    37921 aacggacatg ccagatgctg acgtcgccgc aacgcgaaag ttattgcttg agacgggctt
    37981 cgaagagccg attttcgagc taaacagcca cgacccgcaa agcgtgcagc aactggtgga
    38041 ttatctggca tctctcacca aacaggagga agcaggtgaa aaaactcatc acagcgaatg
    38101 atattcgtga agcacacgcg cgcggcgaac aggcaatgtc cgtggttctg cgcgccagca
    38161 ttattacccc ggaagcccgt gaagtggcag atctactggg ttttaccatc actgaatgtg
    38221 atgaatcgac cccggtaacg gcgtccgttc ccgcctgcgt gccagccgat aaaaccgaaa
    38281 gccagcgtat ccgcgaaacc atcatcgccc agctaccgga aggccagttt accgaaagcc
    38341 tggtcgcgca gctgatggaa aaagtgatga aggaaaaaca gtcactggag cagggtgcaa
    38401 tgcagccgag tttcaaatcg gtgaccggca aaggcggcat caaagttatt gatggcagca
    38461 gcgtcaagtt tggtcgtttc gacggcgcag agccgcattg cgtgggcttg actgatcttg
    38521 tgaccggaga cgacggcagc agcatggccg ccggttttat gcagtgggag aacgcattct
    38581 tcccgtggac cctgaactac gacgaaatcg acatggtgct ggaaggggag ctgcatgttc
    38641 gccacgaagg cgaaaccatg atcgccaaag caggcgacgt aatgtttatc ccgaaaggct
    38701 ccagcatcga atttggtacg acatccagcg tgaaattcct gtatgtcgcc tggccggcta
    38761 actggcaatc cctatgaaag atttcatcac cgaagcatgg ctaagagcga atcatacgct
    38821 tagcgaaggc gcagagatcc atctccctgc ggacagtcgc ctgacgccct ctgcccggga
    38881 gttgctggaa agccgccatc tgcgcatcaa gtttattgac gagcagggcc gcctgtttgt
    38941 tgacgatgaa cagcagcagc cgcagcccgt tcacgggctg accagtagtg atgaacatcg
    39001 gcaggcgtgc tgcgaactgt gccgccagcc ggtggcgaaa aagccggaca cgctgactca
    39061 cctgtcggcg gaaaaaatgg tcgccaaaag cgatccgcgt ctgggttttc gcgcggttct
    39121 cgacagcacc attgcgctgg cagtgtggct gcaaattgaa ctggcggaac cgtggcagcc
    39181 gtggctggcg gacatccgct cgcgtcttgg caacattatg cgcgccgatg cgctggggga
    39241 accgctggcc tgccaagcga ttgtcgggct ttctgacgaa gatctgcatc ggctttctca
    39301 tcagccgctg cgctatcttg gtcacgatca tctggtgccg gaagccagcc acgggcgcga
    39361 tgcggcgtta ctcaatctgc tacgcaccaa agtgcgggaa accgaaaccg tagcggcgca
    39421 ggtgtttata acccgcagtt ttgaagtatt acgcccggac atcttgcagg cgctgaaccg
    39481 cctttcgagc acggtctacg tgatgatgat cctgagcgta acgaagcagc cgctaacggt
    39541 gaagcagatc caacaacgac tgggggaaac gcaatgatta ttgaacgttg tcgtgaactg
    39601 gcgttgcgag cgcccgccag agtggttttt ccggatgcgt tagatcaacg tgtgctgaaa
    39661 gccgcgcaat atttacatca acaaggtctg gcaacgccca ttctggtcgc caatccgttt
    39721 gaacttcgtc agtttgcgct cagtcacggc gtggcgatgg acgggctaca ggtgatagat
    39781 ccgcatggca acctcgcaat gcgggaagaa tttgctctcc gctggctggc ccgtgcgggc
    39841 gaaaaaacgc cgccggatgc gttggaaaaa ctcaccgatc cgctgatgtt cgctgccgca
    39901 atggtcagcg ccgggacagc ggatgtctgt atcgcgggca atctctcttc cacggcgaat
    39961 gtgctgcgtg ccggattacg cattattggc ttacagccag gctgtaaaac gctctcctcc
    40021 attttcctga tgctgccaca gtacagtggc cccgcattgg gctttgccga ttgcagcgta
    40081 gtgccacagc cgacggcggc gcaactggcg gatatcgcgc ttgccagcgc cgaaacctgg
    40141 cgcgccatca ccggagaaga accgcgcgtg gcgatgctgt cgttttccag caacggtagt
    40201 gcccgtcacc cctgcgttgc caacgtccag caggcgacag aaatcgtccg tgagcgcgca
    40261 ccgaagctgg tggtggatgg cgagttgcag tttgacgccg ccttcgtgcc ggaagtggcg
    40321 gcgcaaaaag cgcctgccag cccgctacaa ggcaaggcca atgtgatggt ttttccgtcg
    40381 ctggaagccg gaaatattgg ctacaaaatc gcacaacgac tcggcggata tcgtgccgtc
    40441 gggccattga tacaagggct tgccgcgccg atgcacgatc tctctcgtgg ttgtagcgtg
    40501 caggaaatta tcgagctggc gctggtggca gctgtgccgc gtcagacaga agtgaaccgc
    40561 gaaagcagtt tacaaacact ggttgaatga acggtcccgt tctggaccct gataaagagg
    40621 aaagcacaat ggaagcatta ggaatgatcg aaacccgggg cctggttgca ctgattgagg
    40681 cttctgacgc gatggtgaaa gctgcgcgcg tcaagctggt tggtgttaag cagattggcg
    40741 gcggcctgtg tactgccatg gttcgtggtg atgttgcagc ctgtaaagcc gcgaccgacg
    40801 caggtgccgc cgcggcacag cgtatcggcg agctggtatc tgtacacgtt atcccgcgtc
    40861 cgcacggcga cctggaagaa gtcttcccga tcggcctgaa aggcgatagc agcaacctgt
    40921 aatcaccctg tgtgacgtcg attcgggcgt cacgctctct cctttttcag tttaccttcc
    40981 gcggagggta gggggagctt ttacctgaaa tacgccacgg aggcgggtat gaaactggca
    41041 gtcgtcactg gacaaattgt ttgtaccgta cgccatcacg gactggcgca tgacaaattg
    41101 ctgatggtgg aaatgattga tccacaaggt aatcctgacg ggcaatgcgc cgtcgccatc
    41161 gacaatattg gcgcgggaac cggggagtgg gtgttgctgg tgagtggcag ttccgcccgc
    41221 caggcgcata aaagcgaaac gtcaccggtc gatctgtgcg tgattggcat tgtcgatgag
    41281 gtggtgtctg gcggtcaggt aattttccac aaataaggca gaacatcatg aatcaacagg
    41341 atattgaaca ggtggtgaaa gcggtactgc tgaaaatgca aagcagtgat acgccgcccg
    41401 ccgccgttca tgagatgggc gttttcgcgt ccctggatga cgccgttgcg gcagccaaaa
    41461 ttgcccagca agggttaaag agcgtggcaa tgcgccagtt agccattgct gccattcgtg
    41521 aagcaggcga aaaacacgcc agagatttag cggagcttgc cgtcagtgaa accggcatgg
    41581 gccgcgtcga agataaattt gccaaaaacg ttgctcaggc gcgcggcaca ccgggcgttg
    41641 agtgcctctc tccgcaggtg ctgactggcg acaacggcct gactttaatt gaaaacgcgc
    41701 cctggggcgt ggtggcttcg gtaactccgt ccaccaaccc ggcggcaacc gtaattaata
    41761 acgccataag cctgattgcc gcgggcaaca gcgtcatttt tgccccgcat ccggcggcga
    41821 aaaaagtctc ccagcgggcg attacgctgc tcaaccaggc gattgttgcc gcaggcgggc
    41881 cggaaaactt actggttact gtggcaaatc cggatatcga aaccgctcaa cgtttgttca
    41941 agtttccggg catcggcctg ctggtggtga ccggcggcga agcggtagta gaagcggcgc
    42001 gtaaacacac caataaacgt ctgattgccg caggcgctgg caacccgccg gtagtggtgg
    42061 atgaaaccgc tgacctcgcc cgtgctgctc agtccatcgt caaaggcgcg tctttcgata
    42121 acaacatcat ttgtgccgac gaaaaggtac tgattgttgt ggatagcgta gccgatgaac
    42181 tgatgcgtct gatggaaggc cagcacgcgg tgaaactgac cgcagagcag gcgcagcagc
    42241 tgcaaccggt gttgctgaaa aatatcgacg agcgcggaaa aggcaccgtc agccgtgact
    42301 gggttggtcg cgatgcggcg aaaatcgcgg cggcaatcgg ccttaaagtt ccggaacaaa
    42361 cgcgactgct gtttgtagaa accaccgcag aacatccgtt tgctgtgact gaactgatga
    42421 tgccggtgct gcccgtcgtg cgcgtcgcca acgtggcgga tgccattgcg ctggcggtga
    42481 aactggaagg cggttgccat cacacggcgg caatgcactc gcgcaacatc gaaaacatga
    42541 accagatggc gaatgccatt gataccagca ttttcgttaa gaacggaccg tgtattgccg
    42601 ggctggggct gggcggggaa ggctggacca ccatgaccat caccacgcca accggtgaag
    42661 gggtaaccag cgcgcggacg tttgtccgtc tgcgtcgctg tgtattagtc gatgcgtttc
    42721 gcattgttta aggagtaaca gatggcgcac gacgaacaat ggctcacccc acgtctgcac
    42781 atagcagcaa cgctgtgtaa ccagacgcct gccgcgacgg aatctccgct gtggctgggg
    42841 gtggatctgg gcacctgcga tgtggtgtcg atggttgttg accgcgacgg tcagccggtg
    42901 gcggtatgcc tcgactgggc tgatgtggtc cgcgacggca tcgtctggga tttcttcggt
    42961 gcggtcacca ttgttcgtcg ccatctcgac accctcgagc agcaattcgg tcgccgtttt
    43021 agccatgcgg cgacctcttt tcctccaggt acggacccgc gtatttccat caacgtgctg
    43081 gagtctgccg ggctggaagt gagccatgtg ctggatgagc caaccgcagt cgcggatctg
    43141 ctgcaactgg acaacgccgg tgtagtggat atcggcggcg gcaccaccgg cattgccatc
    43201 gtgaaaaagg gcaaggtgac ttactcggca gatgaagcca ccggcggaca tcatatctct
    43261 ctgactctcg ccggaaatcg ccgtatttcg ctggaagagg cggagcagta caagcgcggt
    43321 cacggtgaag agatttggcc cgcggtgaaa ccggtgtacg aaaaaatggc ggacattgtc
    43381 gcccggcata ttgaagggca gggcattact gatttatggc tggcgggcgg ctcctgtatg
    43441 caaccgggcg ttgcggaact gttttgcaaa caattcccgg cgttacaggt gcatttaccg
    43501 cagcacagtt tgtttatgac cccgctggcg atcgccagta gcgggcgaga gaaagcggag
    43561 gggatctatg caaaatgaat tgcagaccgc gctctttcag gcgttcgata ccctgaatct
    43621 gcaacgggta aaaacattta gcgttccacc ggtgacgctt tgcggtccgg gcgcgatgag
    43681 cagttgcggg cagcaagcgc aaacgcgtgg gctgaaacat ctgttcgtga tggcagacag
    43741 ctttttgcat caggcgggga tgaccgccgg gctgacgcgt agcctggccg ttaaaggtat
    43801 cgccatgacg ctctggccat gtccggtggg cgaaccgtgc atcaccgacg tgtgtgcagc
    43861 cgtggcgcag ttgcgtgaat caggttgtga cggggtgatc gcgtttggcg gcggctcggt
    43921 gctggatgcg gcgaaagccg tggcgttgct ggtgacaaac ccggatagca cgctggcaga
    43981 aatgtcagaa accagcgttc tgcaaccgcg cctgccgttg attgccattc caacgaccgc
    44041 cggaaccggt tctgaaacca ccaacgtaac ggtgattatc gacgcggtga gcgggcgcaa
    44101 gcaggtgtta gcccacgcct cgctgatgcc ggatgtggcg attctcgacg ctgcgctgac
    44161 cgaaggcgtg ccgtcgcatg tcacggcgat gaccggtatc gacgcgttaa cccatgctat
    44221 tgaagcgtac agcgcgctga acgccacacc gtttaccgac agtctggcga ttggcgcaat
    44281 cgcgatgatt ggtaaatcac tgccgaaagc ggtgggctac ggtcatgacc ttgccgcgcg
    44341 cgagagcatg ttgctggctt catgcatggc gggaatggcg ttttccagtg cggggcttgg
    44401 gttatgccac gcgatggcgc atcagccggg ggcggcgctg catattccgc acggtctggc
    44461 gaacgccatg ttgttgccaa cggtgatgga atttaaccgg atggtttgtc gtgaacgctt
    44521 tagtcagatt ggtcgggcgc tgcgaactaa aaaatccgac gatcgtgacg ctattaacgc
    44581 ggtaagtgag ctgattgcgg aagtcgggat tggtaaacga ctgggcgata ttggtgcgac
    44641 atctgcgcat tacggtgcat gggcgcaggc cgcgctggaa gatatttgtc tgcgcagcaa
    44701 cccgcgtacc gccagcctgg agcagattgt cggcctgtac gcagcggcgc aataaaagtg
    44761 tacggacagt cccctcgccc ctttggggag agggttaggg tgaggggaac agagtcgcgc
    44821 cggtgcaaac aattaccctc accccggccc ctcggcttcc agagtgaggg aaaaacccac
    44881 tttcagcatt ggcaataaat aacaactaac agggagtaaa ggcgatggga attaacgaaa
    44941 tcatcatgta catcatgatg ttctttatgc tgatagctgc cgtagacagg atcctgtcgc
    45001 agttcggcgg ttctgctcgt ttcctcggta agttcggtaa aagtatcgaa ggatccggcg
    45061 ggcagttcga agaaggcttt atggcaatgg gcgcactggg cctggcgatg gttggtatga
    45121 ccgcgctggc acctgttctg gcccacgtac tcggaccggt gattatcccg gtttacgaaa
    45181 tgctcggcgc taacccatcg atgttcgccg gaacactgct ggcgtgcgat atgggcggct
    45241 tcttcctcgc caaagagctg gcgggcggcg acgtagcagc gtggctatac tctgggttaa
    45301 ttctcgggtc gatgatgggg ccaacgattg tgttttccat tccggtggcg ctcggcatta
    45361 tcgaaccttc tgaccgtcgt tatctggcgc tcggcgtgct ggcgggcatt gtgaccattc
    45421 cgattggctg tattgctggt ggtctggttg ctatgtactc cggtgtgcag atcaacggtc
    45481 agccggtgga attcaccttt gcgctgatcc tgatgaacat gatcccggta cttatcgttg
    45541 cggtgctggt ggcgctgggg ctgaaattca tcccggaaaa aatgatcaac ggcttccaga
    45601 tcttcgccaa attcctcgtt gcattgatca ccctcggtct tgctgccgcg gtagtgaaat
    45661 tcctccttgg ctgggaactg attcccggtc tggatcctat ctttatggcc cctggcgaca
    45721 aacccggtga agtgatgcgc gccattgaag ttatcggttc tatctcctgc gttctgttag
    45781 gggcgtaccc gatggtactg ctgctgaccc gctggtttga aaaaccgctg atgagcgtcg
    45841 gtaaagtgct gaatatgaac aacatcgcgg cagccggcat ggtggcaacg cttgccaaca
    45901 acatcccgat gtttggcatg atgaagcaga tggatacccg cggcaaagtg atcaactgcg
    45961 ccttcgccgt ttccgctgct ttcgccctgg gcgaccactt aggcttcgcc gctgccaaca
    46021 tgaacgccat gattttcccg atgattgtcg gcaaattgat cggcggcgta acggcgattg
    46081 gcgtggcgat gatgctggtg ccaaaagaag acgcgaccgc ggctaaaacc gaagcggagg
    46141 cacaatcgtg aacactcgcc agctactgag cgtcggtatc gatatcggca ccaccaccac
    46201 ccaggtgatc ttctcccacc tggagctggt taaccgtgcg gcggtgtcgc aggtgccgcg
    46261 ctacgaattc atcaaacgcg aaattagctg gcaaagcccg gtgttcttta cccctgtcga
    46321 taaacagggt ggtttaaaag aagcggaact gaaaacctta atcctcgagc aatatcaggc
    46381 tgcgggcatt gcgccggaaa gcgttgattc tggtgccatc atcatcaccg gtgaaagcgc
    46441 gaaaacccgc aacgctcgcc cggcggtgat gacgctctcc cagtcgctgg gcgattttgt
    46501 cgtcgccagc gccgggccgc atctcgaatc cgtgatcgcc ggtcacggtg ccggggcgca
    46561 aaccctttct gaacaacggc tgtgtcgggt actgaatatc gacatcggcg gtggcaccgc
    46621 gaactacgcc ctgttcgatg ccggaaaaat cagcggcact gcctgcctca acgtcggtgg
    46681 tcgcctgctg gaaaccgaca gccaggggcg cgtggtttac gctcataaac cggggcagat
    46741 gattgtggat gagtgcttcg gcgcaggcac cgacgcccgt tcgctgaccg gcgcgcagct
    46801 ggtgcaggtt acccggcgga tggcagagct gattgtcgaa gtgattgacg gaacgctctc
    46861 gccgctcgcg caggcattga tgcaaaccgg tttgctgccc gcaggtgtta cgcccgaaat
    46921 cattacgctt tctggcggcg tgggcgaatg ttatcgccac cagcccgccg acccgttctg
    46981 ttttgccgat attggcccgc ttctggcaac ggcgctgcat gaccatccgc gcctgcgtga
    47041 gatgaacgtg cagtttccgg cgcaaaccgt acgcgccacg gtgattggcg cgggtgcaca
    47101 taccctttcg ctctctggca gcacaatctg gctggagggc gtacaactgc cgctgcgcaa
    47161 tttgccggtg gcgatcccaa ttgatgaaac ggatctggtg agtgcctggc aacaggcgct
    47221 gattcagctg gatcttgatc ccaattctga cgcgtacgtg ctggcgcttc ccgcctcgct
    47281 gcctgtgcgt tacgccgcgg tactgacggt catcaacgcg ctggtcgatt tcgtcgcgcg
    47341 ttttccgaat ccgcatcccc tgctggtggt ggccgggcag gactttggta aagctctggg
    47401 catgttgttg cgcccacagc tacaacaact cccgttggca gtcattgacg aagtgattgt
    47461 ccgcgcgggg gactatatcg acattggtac gcctcttttt ggcggatcgg ttgtgccggt
    47521 gacggtgaaa tcactcgcat ttccttcctg agggaacgac ttatgaaact aaagaccaca
    47581 ttgttcggca atgtatatca gtttaaggat gtaaaagagg tgctggctaa agccaacgaa
    47641 ctgcgttcgg gggatgtgct ggcgggcgtt gcagcggcaa gctcacagga gcgcgtggcg
    47701 gcaaagcagg tgttgtcgga aatgaccgta gcggacatcc gcaataatcc ggtgattgcc
    47761 tatgaagatg actgtgtgac gcggctgatt caggacgatg ttaacgaaac ggcctacaac
    47821 cagattaaaa actggagcat cagcgaactg cgtgagtatg tgctgagcga tgaaaccagc
    47881 gtggacgaca ttgcctttac ccgcaaaggg ttgacctcgg aagtggtcgc ggcggtggcg
    47941 aagatttgct ccaacgcgga cctgatctac ggcgcgaaga aaatgccggt aatcaaaaag
    48001 gccaatacca ccatcggtat tccgggcacc ttcagcgccc gtttgcagcc aaatgacacc
    48061 cgtgacgacg tgcaaagtat cgctgcgcaa atctacgaag ggctttcctt cggggtgggc
    48121 gatgcggtga tcggcgtcaa cccggtgacg gacgacgtgg aaaacttaag ccgcgtgctg
    48181 gacaccatct acggcgtgat cgacaaattc aacatcccaa ctcagggctg cgtgctggcg
    48241 cacgtcacca cccagattga agcgatccgt cgtggcgcac caggcgggct gattttccag
    48301 agtatctgcg gcagcgaaaa agggctgaaa gaatttggcg tggagctggc gatgctcgac
    48361 gaagcgcgcg cagtgggcgc agagttcaat cgtatcgccg gggaaaactg cctctacttc
    48421 gaaaccggac aaggttcggc gctgtctgct ggcgctaact tcggcgcaga ccaggtgacg
    48481 atggaagcgc gtaactacgg gctggcgcgt cattacgatc cgtttatcgt caacaccgtg
    48541 gtcggcttta ttgggccgga gtatctctac aacgaccgcc agattatccg tgcgggctta
    48601 gaagatcact ttatgggtaa gctgagcggc atctctatgg gctgtgactg ctgctacacc
    48661 aaccacgctg acgctgacca gaacctcaac gaaaacctca tgatcctgct cgccaccgca
    48721 ggctgcaact acatcatggg gatgccgctg ggcgatgaca tcatgctcaa ctatcagacc
    48781 acagcattcc acgacactgc cactgtgcgt cagttactca acctgcgccc gtcaccggag
    48841 tttgaacgct ggctggaaag catgggcatt atggcaaacg gtcgcctgac caaatgggcg
    48901 ggcgatccgt cactgttctt ctgatgacgc ggagataaca catcatggat caaaaacaga
    48961 ttgaagaaat tgtacgcagc gtgatggcgt caatgggaca agcggccccc gcgccgtcag
    49021 aagcaaagtg cgccaccacc acctgtacga caccagtgac ctcggaaagc tgcgcgctgg
    49081 atttaggctc tgcggaagca aaagcgtgga ttggtgtgga aaacccacat cgtgcggatg
    49141 tgttaacaga actgcgtcgc agcaccgtgg cccgcgtttg taccggtcgt gccggtccgc
    49201 gtccgcgtac ccaggcgttg ctgcgtttcc tggccgatca ctctcgttcg aaagataccg
    49261 tactgaaaga agtgccggaa gagtgggtga aagcgcaggg cttgctggaa gtccgctctg
    49321 aaattagcga caaaaatctt tacctgactc gtccggatat gggccgccgc ctgtgtgcag
    49381 aagctgttga agcgctgaaa gcacagtgtg ttgctaatcc ggacgtacag gtcgttattt
    49441 ctgatggcct gtcaactgat gcgatcaccg tgaactacga agagatcctg ccaccgctga
    49501 tggcgggcct gaaacaggcc gggctgaaag tcggtacgcc attctttgtt cgttatggtc
    49561 gcgtgaagat tgaagatcag atcggtgaga tcctcggcgc gaaagtagtg atcctactgg
    49621 tgggggaacg cccgggatta gggcagtcag aaagcctctc ctgctacgcc gtttactcgc
    49681 cgcgtatggc aaccaccgtt gaggccgacc gtacctgtat ctctaacatt caccagggcg
    49741 gcacgccgcc ggttgaagcc gcagccgtca ttgtggattt ggcgaaacgt atgctggagc
    49801 agaaagcatc cggcatcaac atgacccgat aaggaggcat catgccagct ttagatttga
    49861 ttcgaccgtc ggtcaccgcc atgcgggtga ttgcctctgt taacgccgaa tttgcgcgtg
    49921 aactgaaatt gccgccgcat attcgtagcc ttgggctgat ttctgctgat tccgatgacg
    49981 tcacctacat tgcggctgac gaagcgacca agcaggcgat ggtcgaagtg gtgtatggcc
    50041 gctcgctgta tgcgggagct gcacacggac cgtcaccgac tgccggtgaa gtgctgatta
    50101 tgctcggtgg gccaaacccg gcggaagtgc gtgctggtct ggatgcgatg gttgcgcata
    50161 ttgaaaatgg cgcggctttc cagtgggcta atgacgcaga aaacacagct ttcctggcac
    50221 atgtagtttc gcgtaccggt tcttatctct catcaaccgc cgggatcacg cttggcgatc
    50281 cgatggcgta tctggtggca ccgccgctgg aagcgaccta cggcattgat gcggcgttga
    50341 aatctgccga cgtgcagctg gtgacctatg tcccgccgcc gtctgaaacc aactactcgg
    50401 cagcattttt aaccggtagc caggccgcgt gtaaagcagc ctgtaacgct tttaccgatg
    50461 cagtgctgga aatcgcgcgt aatccaatcc agcgtgcgta acggaggttg ccgatgatca
    50521 atgcactggg attgctggaa gtggacggca tggtcgccgc gatagatgca gcggatgcca
    50581 tgctcaaagc agctaacgtt cgtctgctca gtcacgaagt gcttgaccct ggtcgcctaa
    50641 cgctggtggt ggaaggcgat ctggcggcgt gtcgtgcggc gctggacgca ggttgtgctg
    50701 ccgcgatgcg taccgggcgt gtcatcagcc gtaaggagat cggtcggcca gacgatgaca
    50761 cccagtggct ggttactggc tttaaccgcc agccgaagca acccgtaaag gaacccgacg
    50821 cgccagttat cgtcgtggaa tctgctgacg agttgttggc gctgttaaca tcagtacgtc
    50881 agggaatgac ggcaggagaa gtggctgccc actttggctg gccgctggaa aaagccagaa
    50941 atgcgctcga acagctcttt tctgccggga cgttacgtaa acgcagtagt cgttatcgtc
    51001 tcaagcccca ttaacctgtc ggaggtgccg ggtgtcctac aacacccggc attaacatca
    51061 tgaaaaagac ccgtacagcc aatttgcacc atctttatca tgaaccctta cccgaaaacc
    51121 tgaagctcac gccgaaggtc gaagtggata atgttcatca acgacagaca acggatgtct
    51181 atgaacatgc tttgacgatt accgcctggc agcagattta cgatcagctg catccgggca
    51241 agtttcatgg tgaatttacg gaaattctac tcgatgatat tcaggttttt cgtgaataca
    51301 ccggtctggc gctgcgtcag tcgtgcctgg tctggccgaa ctcgttctgg tttggcattc
    51361 cggcgacgcg cggtgagcag ggatttatcg gttcgcaatg tctgggaagc gcagaaatag
    51421 cgacgcgccc tggtggaacc gagtttgaat taagtacgcc ggacgattac acgatcctgg
    51481 gcgtagtgct ttctgaagat gtcatcaccc gtcaggctaa ctttttgcat aatccggatc
    51541 gggtattaca tatgctgcgt agccagtcgg cgctggaagt gaaagaacag cataaagccg
    51601 cgctgtgggg ctttgtccaa caggcgctgg cgacgttttg cgagaatccc gagaatttgc
    51661 atcagcctgc ggtgcgaaaa gtgctggggg ataatttgct catggcgatg ggggcgatgc
    51721 tggaagaagc gcagccaatg gtgacggcgg aaagcatcag tcatcagagt taccgtagat
    51781 tactttcccg cgcccgtgaa tatgtgctgg aaaacatgtc cgaaccggtg acggtgctgg
    51841 acttgtgtaa tcaactgcat gtcagtcgcc gcacgctaca aaacgcgttt cacgctattt
    51901 taggcattgg cccgaacgcg tggctgaaac gcattcgcct gaacgccgta cgccgcgaac
    51961 tgataagccc gtggtcgcaa agcacaacgg taaaagacgc cgccatgcag tggggattct
    52021 ggcatctggg gcaatttgcc acggattacc agcagctgtt tgccgagaag ccgtcgttga
    52081 cgttgcatca gcggatgcgg gaatgggggt gagggagtta cacccaatcc ctgaccttaa
    52141 taaactcact caacgccgct tccgggctgc ctgcttctgg ctgataatcg tactcccagc
    52201 gtaccagcgg cggcattgac atcaggatag actcggtgcg cccgccggtt tgcaggccaa
    52261 acagtgtgcc acgatcccag accagattga actcgacata acgaccacga cgatataact
    52321 ggaaattgcg ctcgcgctcg ccgtaggcca tcgttttacg tcgctctaca attggtaaat
    52381 aagcgttggt gtagcctttg cctaccgcct gcataaaggc aaaacagtgg tcaaagtctg
    52441 gcgtgttcag gtcatcaaag aacaggccgc caatgccgcg ttgttcgtta cgatgtttga
    52501 ggtagaagta ttcgtcgcac cactttttgt aacgcggata aacgtcttcg ccaaatggct
    52561 ggcacaggtc acgggcggtg cggtgccagt gaatagcatc gtcttcaaag ccatagaaag
    52621 gggttaagtc gaagccgccg ccaaaccacc agacgggttc ggcacccggt ttttcggcaa
    52681 taaaaaagcg cacattcgcg tggctggtgg gaacatacgg attatgcgga tgcactacca
    52741 gtgaaacgcc catcgcctcg aaactgcgcc cggcaagttc cgggcgatga gcggtggcgg
    52801 aagcaggcat cgcctcaccg tggacatgcg aaaagttaac gcccgcctgt tcgaaaacac
    52861 caccattacg caacacccgg ctacgtccgc cgccgccagc ttcgcgctgc cagctatctt
    52921 cgacaaattc tgtgccatcg acggtgctca actgctgaca aatcgtatcc tgaaggttga
    52981 gcagaaactg tttaacctgg tgtgcgtcgg gtttcatcac ttaccgcttt ctcgagtgtg
    53041 ctttctggtt gtcaaaccag tggaaaaaac tgatcacgcc ttcggcaatc gctgtggcga
    53101 ttttctggcg aaatgccgcc gtgcctaaca gccgctcttc ttccgggttg gtgataaacg
    53161 aagtttccac cagcaccgaa ggaaccgacg gcgacttcaa caccacaaac gcggcttgtt
    53221 cggtgttgcg gctgtgcagt ttatgcaccg gcttaatctt cttcagaata tgcgagccga
    53281 gcgtcaggct gtttttaata gtatcggttt gcaccagatc aaacagcact tgctgcaata
    53341 ggtgatcctt gtcagtcgcc tttttaccag caacttcatc ggcgcggttt tcgcgttcag
    53401 acaggtattt cgccattgcg ctacttgccc cacggttaga gagggcaaat accgaagcac
    53461 cggcagcttt cgggttggta aagccgtcgg catgaattga cataaacaga tctgcgccat
    53521 gtttatgggc gatttcaacg cgatcgtata gtgggataaa cgtatcgcca gaacgcgtta
    53581 aacgcgcatc aatgccatga ttacgcaaaa tggaacggac gtttttagca atcgccagca
    53641 ccacatgttt ttctttcgaa ccgttgcgtc cgatcgctcc ggtatcaatc cctccgtggc
    53701 ctggatcgag aacaacgaca cgtttgccgc cagatttttt ggctttcggc ttgctgtgtc
    53761 cgttgctggt ttttaaaggt tcgtctttgg cgatggcttg cgacattcct gacaacgtca
    53821 gggcagccaa accggctttc agcacctggc ggcgcgaagt gagtgttttt agtggtttaa
    53881 aagtgctcat acggcctgag ttgtaataat aaagttccag atgttatatc gtatcgcgta
    53941 atccgttacg accgtttgct gatgagaatt gttttacttt tcatttcaat agttgacaac
    54001 tccccattat gccacttttt caaccgattt tcgtcagata ttggctaatt cgaccgttca
    54061 cgccataatc agccttttaa cccgcaaaaa ggtaacgaat accatggaga tacgcgtatt
    54121 tcgccaggaa gatttcgaag aggtcatcac cctttgggag cgttgcgact tgctgcgtcc
    54181 gtggaacgat ccggaaatgg acatcgagcg taagatgaac catgacgtca gtttgtttct
    54241 ggtcgctgag gtaaacggtg aagtggtcgg aacggtgatg ggcggttatg acgggcatcg
    54301 cgggtctgct tattatcttg gcgtgcatcc agagtttcgt gggcgtggga ttgccaatgc
    54361 gttgcttaat cggttggaga aaaagctgat tgctcgcggc tgcccgaaaa ttcagatcaa
    54421 cgtgccggaa gataacgaca tggtgctcgg aatgtatgaa cgcctgggat atgaacacgc
    54481 cgacgtgctg agtttgggta agcgtttgat tgaagatgaa gagtactgag tttcatcctg
    54541 tccattatga tgcgcacggt cgcctgcgtt tacccttgct cttctggctt gtgctattgc
    54601 ttcaggcgcg aacctgggtg ctgtttgtca ttgccggtgc gtcgcgcgag cagggtactg
    54661 cactgctaaa tctgttttat cccgatcacg ataatttctg gctggggttg attcccggca
    54721 ttccggcggt gctggcgttt ttgctgagtg gtcggcgggc ttcatttccc cgtatctggc
    54781 atgtgctcta ttttctgttg ctgttggcgc aggtggtttt actttgctgg caaccgtggc
    54841 tgtggctgaa cggtgaatcc gttagcggta tcgggctggc gctggtagtg gcggatattg
    54901 tggcgttaat ctggctgctg accaatcgac gtttacgcgc ttgttttaat gaagaaaaag
    54961 aataacggca ctttttggtg aatttgcact ccaagcaacg ttattgaata accaaaggaa
    55021 gtgacatgat atcgctgcgt ttaatgttat gcgctatgcc gttgatgctg accggctgtt
    55081 ccacgatgtc gtcagttaac tggtctgccg ctaacccgtg gaactggttt gggtcgtcca
    55141 ccaaagtgag cgagcagggc gttggtgaat taacggcgtc cacaccactg caagaacaag
    55201 ccattgctga tgcgcttgat ggcgattatc gcctgcgcag cggaatgaaa accgcgaacg
    55261 gcaacgtggt gcgctttttt gaagtgatga aaggcgacaa cgtggcgatg gtgattaacg
    55321 gcgatcaggg cacgatcagc cgcattgatg tgctggatag cgatattcca gctgactcca
    55381 gtgttaaaat cggtacaccg tttagcgacc tttacagcaa agcatttggc aattgccaaa
    55441 aagctgatgg tgatgataat cgtgccgtcg aatgtaaagc cgaaggcagt caacatatta
    55501 gctaccagtt cagcggggaa tggagtggtc ctgaagggtt aatgccttcg gacgataccc
    55561 tgaaaaactg gaaagtcagt aaaattatct ggcggcgtta atttgcgtct gaacaaaccg
    55621 ccgccgcgaa aaaacacgta aaatagcgcc caacaatgcc acggattgcg tggcattctt
    55681 attttcagga ggaataatgt ctcaggttca gagtggcatt ttgccagaac attgccgcgc
    55741 ggcgatttgg atcgaagcca acgtgaaagg ggaagttgac gccctgcgtg cggccagtaa
    55801 aacatttgcc gataaactgg caacttttga agcgaaattc ccggacgcgc atcttggtgc
    55861 ggtggttgcc tttggtaaca acacctggcg cgctctgagc ggcggcgttg gggccgaaga
    55921 gctgaaagat tttccgggct acggtaaagg ccttgcgccg acgacccagt tcgatgtgtt
    55981 gatccacatt ctttctctgc gtcacgacgt aaacttctct gtcgctcagg cggcgatgga
    56041 agcctttggt gactgcattg aagtgaaaga agagatccac ggcttccgtt gggttgaaga
    56101 gcgtgacctg agcggcttcg ttgacggtac tgaaaacccg gcgggtgaag agacgcgccg
    56161 tgaagtggcg gttatcaaag acggcgtgga tgcgggcggc agctatgtgt ttgtgcagcg
    56221 ttgggagcac aacctgaagc agctcaaccg gatgagcgtt cacgatcagg agatgatgat
    56281 cgggcgcacc aaagaggcca acgaagagat cgacggcgac gagcgtccgg aaacctctca
    56341 cctgacccgc gttgatctga aagaagatgg caaagggctg aagattgttc gccagagcct
    56401 gccgtacggc accgccagtg gcactcacgg tctgtacttc tgcgcctact gcgcgcgtct
    56461 gcataacatt gagcagcaac tgctgagcat gtttggcgat accgatggca aacgtgatgc
    56521 gatgttgcgt ttcaccaaac cggtcactgg cggctattac ttcgcgccgt cgctggacaa
    56581 gttgatggcg ttgtaatcgt ttctgattcg atgatttaag gccagccagt atcacaactg
    56641 actggccttt ttgtgcacag aaaaccccca gctaggctgg gggttccgga aagctttcag
    56701 ctttaagcca gttattaaaa ccccttttga tttgttaaaa caccttgcgg tctggcaact
    56761 gcaagtgtca aacaagaaat caaaaggggg tcccaatggg gaacgaaaag agcttagcgc
    56821 acacccgatg gaactgtaaa tatcacatag tttttgcgcc aaaataccga agacaggtgt
    56881 tctacagaga gaagcgtaga gcaataggca gtattttgag aaagctgtgt gagtggaaaa
    56941 gtgtacggat tctggaagct gaatgctgtg cagatcatat ccatatgctt gtggagatcc
    57001 cgcccaaaat gagcgtatcc ggctttatgg gatatctgaa agggaaaagc agtctgatgc
    57061 tttacgagca gtttggtgat ttgaaattca aatacaggaa cagggagttc tggtgcagag
    57121 ggtactacgt cgatacggtg ggtaagaaca cggcgaagat acaggattac ataaagcacc
    57181 agcttgaaga ggataaaatg ggagagcagt tatcgattcc ctatccgggc agcccgttta
    57241 cgggccgtaa gtaacgaagt tggatgcaaa tgtcagatcg tgtgcgcctg ttagggcgcg
    57301 gctggtaaga gagccttata ggcgcatttg aaaaacctcc ggctatgccg gaggatattt
    57361 attattactg ctttaacgcc gcatacacct gatcaactac ccaaccataa gttgcaatcg
    57421 gtagctgacc gctttcgaac atattgggat ttttttgtgg atcggcaact ggcgaatgtg
    57481 gcttgttgct taacatcaca atcgccatat gattcaccgg atcgataacg gtcaccgtcc
    57541 cggtccagcc agtgtgaccg taggtttgcg ggcttgccag cgtgccaaac gtcggcgtca
    57601 tggtggcatt accattcacg cgccagccaa ggccaaaagt ggcatcttcc ttagagctgg
    57661 tggtgaacat cttcaccgtt tctgcattga acaactgcac atcgccatag ccgccgccgt
    57721 tcagcatcgt ttgcattaac accgcaatat cgccggtatt ggaaaacaac cctgcatgcc
    57781 cggaaacgcc gcccatcgaa taaaaggctt tttcatcgtg cacctgaccc cagagagtgg
    57841 aggtgcggat atccgggaaa tggatcacgc catcgcgggt attgccgttg agttccgtgg
    57901 cggcaatttg ttgcggttta aagcctttca gtagcggatt aaacaccgta tgcgtcaggc
    57961 cgagcgggcg ataaatcgac tcttcaacat agcggtcaag tggctgaccg gtaaccgact
    58021 cgacgataaa tccaagcagc atataatcga catcgctgta gatatgcttg ctgccgggct
    58081 gatactccag cggcgtgcgc ttgatcatct ccagcgtctg gcctttatcc tgggaatata
    58141 acgcgcccgc gaccgcttta ttcggatatt gtgggtccgc cgggaaaccg ccgctgtgat
    58201 gcagcaggtc agaaatccgc agcgtgtttt tgcctttgat ggtgtcattt ggactatcgg
    58261 caaatcccgg aatatatttc gcaatccgat cgtcaggatg cagcttgcct tcgctcatta
    58321 gcttttgcag agcaaagtta gtggcgtaca tcttggtatt ggaagccagg tcatacagcg
    58381 tcccggtggt ggctttgaca ggctgttcca tcaatacgct gccatcgtac tttttcgccg
    58441 ctccccaggc tttgcgatac acaatctgat tatctttaat aatcagcagg tttacgccgg
    58501 gataaccggc atccacctgc tggcttatcc agcgatccat ctggttaagc cgttcgacgt
    58561 tgaaccctgc tttctctggc gaactttctg tcagaacagg gtattttgcg gcgctgacgc
    58621 tacagctgac agccagcaga gaaagataga gcattgtccg tttcatatta tcagtccaga
    58681 ttgacgttac ggcagccaaa gagcgtggtg aaaataaacc cgcaaaccca tgccaccaga
    58741 atcccgcctg cataaaccgc cattgccgga aggatgcctt gtgcggaagt catcagcggc
    58801 agcgccacca gaccagacgg cccaaaggcg ctgtttaagc ccatcggcag accccaccag
    58861 gctatcaatc cgataaacaa accgcccgcc gcgccgccta aacaggcggt aataaacggt
    58921 ttcatgcggg gcagggtgac gccataaatc aacggttcgc caacgcccag caggccggga
    58981 ataatcgccc cgcgtacctg actgcgtaat gcactgtgcg gttgcgcccg ccagtagagt
    59041 gccagcgccg cgcccacctg gcccgcgcct gccatcgaaa ggatgggaaa taagctgttg
    59101 aatccctgac tgtccattaa cgcgaggtaa acaggaataa agccctgatg cacgccaaac
    59161 accacggcga tcaggaacag cccggctaaa accgcacaac cgagcggatt actgttcagg
    59221 tgcataaaca gccacgacat gccttcaaac agccagccgc ccagcggcat aatgatcagg
    59281 taggccagcg tagcggtgat cagcagggtg attaacgagg tcaacagcat gtcgagatcg
    59341 tccggcataa agcggcgcac catgccttcg atgcgggcgc aggcccacgc ggcaatcaac
    59401 acgccgataa tattgccgcg cggatcgatg ggcagaccaa agaaatcgtg aaaaccggcg
    59461 tagtaaccgg tggttgcagt tgggttataa ccgagcaaaa agagcgcggc gataatcgcg
    59521 ccatttacgc ccgtgccgcc aaatgcctgg gcggcgttat agcccaccag aatcaccagg
    59581 aaggtgaaca aacctttgct gaacaccttc ataaaattca gcgcgtcggg tagcgtgccc
    59641 tgagcatctg ccggaacgtg catcaccgtg gcaattaacg tcgctatccc cagcagcaga
    59701 ccggcggcaa taaaaccggg gatcagcggc gtgaagatgg tggcgaattt ggcgagaaat
    59761 tgttgcacgc cggaggtttg tttggctttt aactgacgtt tgttctgggc ggcgatttct
    59821 gcggcatcct gtaccggtgc ttctcccagc agctcgctca tggcttttgc ggcacgatgc
    59881 gctttgcccg gcccaaaaac cacctgcacc tgatcgctgg tcaaaatgac gcccttcacg
    59941 ccttccagcg ttttgatatt gggatcaacc agtgaactgt catgtacacc cagacgcagg
    60001 cgcgtcatac agttaccaca actggcgata tttcccggtc cgccgacacg ggtaagaatg
    60061 gtgttcagaa gttcactgct gatctctttg gccatgggtt attccttgtc taaaacctga
    60121 cgaataaagc cgccgtgttg atcaaggcgt tttttagctt ctgcggcatc gagatttttc
    60181 agcaccatca caatggccgt tttacagttg cgctcgcagg caaccaatgc cgcttccgct
    60241 tgctctgcgc tacatccggt agcgtttttg acgatattga cctggcgcac atgcaatttt
    60301 tcgttggtgg cgaccacatc gaccatcagg ttgccgaaca ctttgccgga tttaatcatc
    60361 agcccggtgg agagcatatt gagcaccagt ttctgcgccg tacctgcttt cattcgcgaa
    60421 gaacctgtga ccacttcggc cccaacaact ggcgtaatgg caaactcagc ggtggttgaa
    60481 acggcgctcc cgggattaca ggaaattccc actgtgcggc aaccgagctg gcgggcgtat
    60541 tccagtccgg caatcacata cggcgtacga ccgctggcgg caataccgac caccacatcc
    60601 tgtgccgtta aattaatatt tttcagatcg ttaacgccgc cttcccggct atcttccgcg
    60661 ccttccaccg cgtgctgaat ggcatattcg ccgccagcaa tcaaaccaac taccaggccc
    60721 ggtttcacgc cgtaggtcgg cggacattca ctggcatcaa gaatacccag acgaccggat
    60781 gttcccgcac cgagataaat cagacgcccg ccgccgctta cctgggcgtg gataacatcg
    60841 atcgccgcgg cgatatccgg cagtacgcgc tcaacggcaa gcggcacggt tttatcttca
    60901 tcgttgataa tccggcacat ttccagcgtt gatacgcggt caatttcagc tgaggcggcg
    60961 ttcgagcctt cggtaatcat cttttcaagt tgcatcggtg gtgaccttac tatttacgat
    61021 caaataattg cagatgtatg gaatcatata tcccgaattg acagacttaa aggaatcatt
    61081 gagtctacac tcgcagagtg tgaagagcgt cataagaact taagcggaat ttttgctgcc
    61141 agcccaggag agtggaagat gttgtacctg acgaaaatac gcaatgcgga aagtgaattt
    61201 accgggaacg agcaaaaaat tgctgacttt ctgcgggcta atgtgagtga gctgaaatct
    61261 gtctcttcgc gcaagatggc gaaactgctc ggcatcagcc agtcgagtat tgtgaagttt
    61321 gcccagaagc tcggcgcgca aggatttact gaattgcgta tggcgttaat tggcgaatac
    61381 agtgccagcc gggagaaaac gaatgccacg gcgctgcacc tgcacagttc gattaccagt
    61441 gatgattcgc tggaagtgat tgcccgcaaa ctgaatcgcg aaaaagagct ggcgctggag
    61501 caaacctgcg cgttgttcga ctacgcgcgg ctgcaaaaaa tcattgaggt catcagtaaa
    61561 gcgccattta tccagataac gggcctgggc gggtcggcgc tggtggggcg cgatctttca
    61621 ttcaaactga tgaaaattgg ttatcgtgtg gcctgtgaag ctgacacgca tgtacaagcc
    61681 accgtttccc aggcgctgaa aaaaggcgat gtacaaatcg ctatctctta cagcggcagt
    61741 aaaaaagaga ttgtcttgtg cgccgaggca gcgcgaaagc agggggcaac ggtgattgcc
    61801 attacctcat taaccgattc cccgctgcgg cggctggcgc attacactct cgataccgtt
    61861 tctggcgaaa ccgaatggcg cagctcgtcg atgtccaccc gcacggcgca aaattctgtt
    61921 accgatttac tgtttgttgg ccttgtgcaa ctcaatgatg tggagtcatt gaaaatgatt
    61981 gagcgcagca gtgagctaac gcaacgcctg aaatgatgca taaagcagcg actggattga
    62041 gattttcctg aattagtgag ctgatccgca gcaatatttt gtttatcctg tattttcaga
    62101 gggaatggag tgtaacgctc tgtattaaca aggagagcat taaaatgggt aaactcacgg
    62161 gcaagacagc actgattacg ggcgcattgc agggaattgg cgaaggaatt gccagaactt
    62221 ttgcgcgtca tggcgcaaac ctaatcttgc tggatatctc ccctgagatc gaaaagctgg
    62281 cggacgaact gtgtggtcgt ggtcatcgct gtacggcggt tgtcgccgat gtgcgtgacc
    62341 cggcgtcggt cgccgcagct atcaagcgcg cgaaggaaaa agaagggcgc attgatatcc
    62401 tggtgaataa cgcaggcgtt tgtcgtctgg gcagtttcct cgatatgagc gatgaagatc
    62461 gcgatttcca tattgatatc aatattaaag gcgtatggaa cgtcacgaag gcggtgctgc
    62521 cggagatgat tgcccgcaaa gatggtcgca ttgtgatgat gtcttcagtc actggcgata
    62581 tggtggccga tccgggtgaa acggcgtatg ccttaacgaa agcggcgatt gttggcctga
    62641 ctaaatcgct ggcggtggag tacgcgcagt ctggtattcg cgttaacgcc atctgcccgg
    62701 gatacgtacg cacgccaatg gcggaaagca ttgcccgcca gtcgaacccg gaagatccag
    62761 aatcggtgct gactgaaatg gcaaaagcaa tcccgatgcg tcgcctcgcc gatccgctgg
    62821 aagtcggcga actggcagcc ttcctcgcat cggatgaatc aagttattta accggtacac
    62881 agaatgtgat tgatggcggc agcacactgc cggagacggt tagcgtcggc atctgattca
    62941 cctctgtttc ctccctgcat ttgtggggag gatttcgtct tgaacccggt tcttattccc
    63001 ttttcaactt ccaaatcacc aaacggtata taaaaccgtt actcctttca cgtccgttat
    63061 aaatatgatg gctattagaa agtcattaaa tttataaggg tgcgcaatgg ccgttaactt
    63121 actgaaaaag aactcactcg cgctggtcgc ttctctgctg ctggcgggcc atgtacaggc
    63181 aacggaactg ctgaacagtt cttatgacgt ctcccgcgag ctgtttgccg ccctgaatcc
    63241 gccgtttgag caacaatggg ccaaagataa cggcggcgac aaactgacga taaaacaatc
    63301 tcatgccggg tcatcaaaac aggcgctggc gattttgcag ggcttaaaag ccgacgttgt
    63361 cacttataac caggtgactg acgtacaaat cctgcacgac aaaggcaagc tgatcccggc
    63421 cgactggcaa acgcgcctgc cgaataacag ctcgccgttc tactccacca tgggcttcct
    63481 ggtgcgtaag ggtaacccga agaatatcca cgactggaac gatctggtgc gctccgacgt
    63541 aaagctgatt ttcccgaacc cgaaaacgtc gggtaacgca cgttacacct atctggcggc
    63601 atggggtgca gcggataaag ctgacggtgg cgacaaagcc aaaaccgaac agtttatgac
    63661 ccagttcctg aaaaacgttg aagtgttcga taccggcggt cgtggcgcga ccaccacctt
    63721 tgccgagcgc gggctgggcg atgtactgat tagctttgaa tcggaagtaa acaacattcg
    63781 taaacagtat gaagcgcagg gctttgaagt ggtgattccg aaaaccaata ttctggcgga
    63841 attcccggtg gcgtgggtcg ataaaaacgt gcaggccaac ggtacggaaa aagcagcaaa
    63901 agcttacctg aactggctct acagcccgca ggcgcaaacc atcatcaccg actattacta
    63961 ccgcgtaaat aacccggaag tcatggacaa actgaaagac aaattcccgc agaccgaact
    64021 gttccgcgtg gaagacaaat ttggctcctg gccggaagtg atgaaaaccc acttcaccag
    64081 cggcggcgag ttggacaagc tgttagcggc ggggcgtaat taatgtttgc agtttcatca
    64141 agacgcgtgc tgccgggctt taccttaagc ctcggcacca gtctgctgtt tgtgtgcctg
    64201 attttgctgc tgccgctctc cgcgctggtg atgcagctct ctgagatgag ctgggcgcag
    64261 tactgggagg tgatcaccaa cccgcaggta gtcgcggcct acaaagtgac actgctgtcg
    64321 gcgtttgtgg catcaatttt taacggcgtt ttcggcctgc tgatggcgtg gattttaacc
    64381 cgttatcgct ttccgggccg cacgctgctt gatgcgctga tggatttacc ctttgcgcta
    64441 ccgacggcgg tagccggttt gacgctggcc tcgctctttt ccgtgaacgg tttttacggt
    64501 gaatggctgg cgaagtttga tatcaaagtc acctatacct ggctggggat tgcggtggcg
    64561 atggccttta ccagcattcc gtttgtggtg cgtaccgtgc agccggtgct ggaagagtta
    64621 ggcccggaat atgaagaagc ggcggaaacg ctcggcgcaa cgcgctggca gagtttctgc
    64681 aaagtggtgc tgccggagct atctccggcg ctggtggcgg gcgtggcgct gtcgtttacc
    64741 cgtagtcttg gtgaatttgg cgcggtgatt tttatcgccg ggaacatcgc ctggaagaca
    64801 gaagtgacgt cgctgatgat ttttgttcgc ttacaggagt ttgattaccc ggcggcgagc
    64861 gcgattgctt cggtgatcct cgcggcatcc ctgctgctgc tgttctcaat taacactctg
    64921 caaagtcgct ttggtcggcg tgtggtaggt cattaatggc ggaagtgaca cagttgaagc
    64981 gttatgacgc gcgcccgatt aactggggca aatggtttct gattggcatc gggatgctgg
    65041 tttcggcgtt catcctgctg gtgccgatga tttacatctt tgtgcaggcg ttcagtaaag
    65101 ggctgatgcc agttttacag aatctggccg atccggacat gctgcacgcc atctggctga
    65161 cggtgatgat tgcgctgatt gccgtgccgg tgaacctggt gttcggcatt ctgctggcat
    65221 ggctggtgac gcgctttaac ttccccggac gccagttgct gctgacgctg ctggacattc
    65281 cgtttgccgt gtcgccggtg gttgccggtc tggtgtatct gctgttttac ggctctaacg
    65341 gcccgctcgg cggctggctg gatgaacata atctgcaaat tatgttctcc tggccgggaa
    65401 tggtgctggt caccatcttc gtgacgtgtc cgtttgtggt gcgtgagctg gtgccggtga
    65461 tgttaagcca gggcagccag gaagacgaag cggcgatttt gctgggcgca tctggctggc
    65521 agatgtttcg ccgcgtcacg ctgccgaaca tccgctgggc gctgctttat ggcgtggtgc
    65581 tgaccaacgc ccgcgcgatt ggcgagtttg gtgcggtgtc ggtggtttcc ggctcgattc
    65641 gcggcgaaac actttcgctg ccgttacaga ttgaattgct ggagcaagac tacaacaccg
    65701 tcggctcctt taccgctgcc gcgttgttga cgctgatggc gattatcacc ctgtttttaa
    65761 agagtatgtt gcagtggcgt ctggagaatc aggaaaaacg cgcgcagcag gaggaacatc
    65821 atgagcattg agattgccaa tattaagaag tcttttggtc gcacccaggt gctgaacgat
    65881 atctcactgg atattccttc tggtcagatg gtcgcgttgc tggggccgtc cggttccggg
    65941 aaaaccacgc tgctgcgcat tatcgccggg ctggagcatc aaaccagcgg gcatattcgc
    66001 ttccacggca ccgacgtcag ccgcctgcat gcgcgcgatc gtaaagttgg tttcgtgttc
    66061 cagcactatg cgctgttccg ccatatgacg gtgttcgaca atatcgcttt cggcctgacg
    66121 gtgctgccgc gtcgcgagcg cccgaatgcc gcagctatca aagcgaaagt gacaaaattg
    66181 ctcgagatgg tccagcttgc ccatctggcg gatcgttatc cggcgcagct ttccggcggc
    66241 cagaaacagc gtgtggcact ggcgcgtgcg ctggctgtag aaccgcaaat tctgctgctt
    66301 gatgaaccgt ttggcgcgtt ggatgctcag gtgcgtaaag agctgcgtcg ctggctgcgt
    66361 cagttgcatg aagagctgaa attcaccagc gtgttcgtga cccatgacca ggaagaggcg
    66421 accgaagtag ccgatcgtgt agtggtgatg agccagggca atatcgagca ggctgatgca
    66481 ccggaccagg tatggcgcga accagcgacc cgttttgtac tcgaatttat gggcgaagtg
    66541 aaccgcctgc agggaaccat tcgcggcggg cagttccatg ttggcgcaca tcgctggccg
    66601 ctgggctata cacctgcgta tcaggggcca gtggatctct tcctgcgtcc gtgggaagtg
    66661 gatatcagcc gccgtaccag cctcgattcg ccgctgccgg tacaggtact ggaagccagc
    66721 ccgaaaggcc actacaccca attagtcgtg cagccgctgg ggtggtacaa cgaaccgctg
    66781 acggtcgtga tgcacggcga cgacgccccg caacgtggcg agcgtttatt cgttggtctg
    66841 caacatgcgc ggctgtataa cggcgacgag cgtattgaaa cccgcgatga ggaacttgct
    66901 ctcgcacaaa gcgcctgata ggttgagtga atgttaaacg cccggaggcg cttcccgcga
    66961 tccgggcttt ttaatggcaa ggtttgtaac ctgtaggcct gataagacgc gcaagcgtcg
    67021 catcaggcaa caccacgtat ggacagagat cgtgagtaca ttagaacaaa caattggcaa
    67081 tacgcctctg gtgaagttgc agcgaatggg gcctaataac ggcagtgaaa tctggttgaa
    67141 actggaaggc aataacccgg caggttcggt aaaagatcgt gcggcacttt cgatgatcgt
    67201 cgaggcggaa aagcgcgggg aaattaaacc gggggacgtg ctgatcgaag ccaccagtgg
    67261 taacaccggc attgcgctgg caatgattgc cgcgcttaaa ggctatcgca tgaaattgct
    67321 gatgcccgac aacatgagcc aggaacgccg tgcggcgatg cgtgcttatg gtgcggaact
    67381 gattcttgtc accaaagagc agggcatgga aggtgcgcgc gatctggcgc ttgaaatggc
    67441 gaatcgtggt gaaggaaagc tgctcgatca gtttaataat cctgataatc cctacgccca
    67501 ttacaccacc accgggccgg aaatctggca gcaaactggc gggcgcatta cccattttgt
    67561 ctccagcatg ggaacaaccg gcactatcac cggcgtttca cgctttatgc gcgaacaatc
    67621 caaaccggtg accattgttg gcctgcagcc ggaagagggc agtagcattc ccggcattcg
    67681 ccgctggcct gcggaatatc tgccggggat tttcaacgct tctctggtgg atgaggtgct
    67741 ggatattcat cagcgagaag cggaaaacac catgcgcgaa ctggcagtgc gggaaggaat
    67801 attctgtggc gtcagctccg gcggcgcggt tgccggagca ctgcgcgtgg caaaagctaa
    67861 ccccggcgcg gtggtggtcg cgatcatctg cgatcgcggc gatcgctacc tttctaccgg
    67921 ggtgtttggg gaagagcatt ttagccaggg ggcggggatt taagattatt gcgcaggcac
    67981 cgttttatcc gtctgcgcaa tcagcgcatg taaaaaaggt tgcgcatttt catcgctctt
    68041 accgggcatc ttcacaatat acggcttccc ggtaatcgat gacgacgagg ccaccttatc
    68101 aataaactgc tcggcggtat caatgcggtt gcgcgtgttg ccgaacttca gacgcaggtg
    68161 ggaaaccgct tcatcacagg tgtgttcatc gccgttacgc acaaatatca aatccttttt
    68221 ctgtgctaat ccctccagca tggcgttgat acgggcttct tcatgggcag ttaacttcgc
    68281 gtaaacgggg agtgtcatta gcagcgtaat gaccagacaa atgattttct tcattgaatt
    68341 accttatcct tgttttgtga tagccgattt gactgccaga atcaggtaaa gtttcggttg
    68401 gaatacgatg aggatcatcg gcaaggagaa aaaattaaat gagtagtttg ttgttgttta
    68461 acgataagag cagggcattg caggcagata tcgtcgccgt gcagtcgcag gtagtgtacg
    68521 gcagcgtagg caacagcatt gccgtgcctg ctatcaaaca gaacggcctg aatgtctttg
    68581 ccgtgccgac ggtattgctg agcaatacac cgcattatga cactttctac ggtggtgcga
    68641 ttccggacga atggtttagc ggctatttgc gtgcgcttca ggagcgtgat gcgttgcgcc
    68701 aacttcgtgc tgtaaccacg ggctatatgg gaacggcatc gcaaatcaaa atccttgccg
    68761 agtggctgac tgcgctacgc aaagatcatc ctgacctatt gatcatggtc gatccagtga
    68821 ttggcgatat tgatagcgga atttatgtca aacctgacct tcccgaggcg tatcgacaat
    68881 atttactgcc gctggcgcag ggaattaccc ccaatatctt tgagctggaa atcctgaccg
    68941 gtaaaaattg ccgcgatctc gacagtgcca ttgctgccgc aaaaagtctg ctttcagaca
    69001 cattaaaatg ggtggtgatt accagcgcct ccggtaatga agaaaatcag gagatgcagg
    69061 tggtggtggt cagtgccgac agcgtgaatg tcatttccca ttcacgggta aaaaccgacc
    69121 tgaaagggac tggcgacctg ttttgtgctc agcttatcag tggtttgctg aaagggaagg
    69181 cgttaaacga tgcggtgcac cgtgcggggt tgcgcgtact ggaagtgatg cgctacaccc
    69241 agcagcatga gagcgatgaa ttgattttgc cgccgctggc ggaagcataa aaaatggcgc
    69301 cgatgggcgc catttttcac tgcggcaaga attacttctt gatgcggata accggggttt
    69361 cacccacagt cacgctaccg gacagtttga tcagttcttt gatttcgtcc atgttggaga
    69421 taacaaccgg agtcagggta gacttggctt tctcttccag cagcggcaga tcaaattcaa
    69481 tgacagtatc gccaactttc acgcgctgac cttcttcagc aatacgcttg aagccttcgc
    69541 ctttcagttc aacggtgtcg ataccgaagt ggacgaacag ttcaacgccg ctatcagatt
    69601 cgatagagaa cgcgtggttg gtttcaaaga ttttaccaat ggtgccgtct acaggcgcga
    69661 ccattttgtt tccagttggt ttgatagcaa taccatcacc aacgattttt tccgcaaaaa
    69721 cgacatccgg cacgtcttcg atattgacga tctcgccaga gagcggagca atgatctcaa
    69781 tagttccggt atccttcttg tcgtcggaaa ccagagattt cagtttatcg aacaaaccca
    69841 tgatcttctc ctaagcagta aattgggccg catctcgtgg attagcagat tgttttttct
    69901 tcaatgaact tgttaaccag cgtcattaac tcgtccgttg tcggttgagc aagagcctgc
    69961 tctgctaaca ccttcgcatc ttcgaagttc gtgttacgga taatcttctt aatgcgcggg
    70021 atagaaatgg cgctcataga gaattcgtcc agacccatcc ccagcaacag aagtgtagca
    70081 cgttcgtcgc ctgcaagctc accacacatg ccagtccatt tgccttcagc atgagaagca
    70141 tcaataactt gcttgatcaa gttcagcacg gacggtgaca ttggctggta aaggtgtgaa
    70201 atcatatcat taccacggtc aactgccaga gtgtactgcg ttaaatcatt ggtgccgata
    70261 ctaaagaaat caacttcttt ggctaaatga cgtgcaattg ttgcggcagc cggtgtttcc
    70321 accattacgc cgatttcaat tgactcgtca aacgctttac cttcgtcgcg cagttcctgt
    70381 ttgtagattt cgatctcttt gcgcagtgca cgcacttctt caacagagat gatcatcggg
    70441 aacataatgc gcaatttacc gaaagccgag gcacgcagga tagcgcggag ctgatcgcgc
    70501 aggatctctt tacgatccat cgcgatacgg atagcgcgcc agccgaggaa cgggttctct
    70561 tctttcggga agttcatgta tggcagctct ttgtcgccgc cgatgtccat ggtacgaacg
    70621 ataaccgcct gcgagccaca cgcttcagcc actgctttgt aagcagcaaa ctgttcttct
    70681 tcagtgggca gcgcgtcgcg gtccatgaac agaaactcag tacgatacag accaacgcct
    70741 tcagcgccgt tacgctctgc accttcaacg tcacgaaccg taccaatgtt agcgcacact
    70801 tctacctggt gaccgtccag cgtaatagct ggcagatctt tcagtttagc aagctctgct
    70861 ttttcagaag ccacttgctc ctgaacagcg cgcattttat caataacttc gttggttgga
    70921 ttgacgtaaa cctgattatt tacggcatcc agaatcagat agtcgtcatt tttcacctga
    70981 gaggtgacgc taccggtacc cacgatagca ggcagttcca gagaacgcgc catgatagag
    71041 gtgtgggaag tacggccacc cgcgtcggtg atgaaaccca gcaccttctt caggttcagc
    71101 tgtgcagttt cggacggcgt caggtcagcg gcaaccagaa tgacttcatc ctgaatggcg
    71161 ctcaggtcga taatcttcag gcccaggatg ttgcgcagca ggcgcttacc gatatcacgt
    71221 acgtcagccg cacgttcttt caggtattca tcatccagct cttccagggc agaagcctga
    71281 ccttcgataa cttcatgagc agctgcgtca gctgtcatgt gcttatcttt aatcagggct
    71341 atgatttcct gctccagctc ctcatcttcg agcagcataa tatgcccttc aaagatggct
    71401 tctttttctt caccgaacgt ttcaccagct ttcgttttga tcgtttccag ctgggctgat
    71461 gccttggcac gaccgctcag aaaacgttca acttcctgat caacctggtc ggcagaaatt
    71521 tttttccggt caatgacaat ttcgtcttct ttcagaagca gagctttacc gaaagcgata
    71581 cccggggatg ctaaaatgcc tgaaatcata accctacctt acttgtgact gatttttaaa
    71641 agaacccggg aaattactcg agttccgcca tcagtttaac cagatgttca accgctttct
    71701 gctcgtcttc gccttctgcg gagatagtca caacggtacc ttgagtcagg cccagagtct
    71761 gcagtttaaa caggcttttc gcgctggcgc ttttgccgtt ggaagtcaca gtaatttcag
    71821 aagtgaagcc cttagcttct tttacaaact gggcagcagg gcgggtgtgc agaccgttcg
    71881 gagcggtaat ggtaacttct tgctggaaca ttgtatttcc ccaacttata ggtttagtgt
    71941 tgtggaacta aagtctagcc tggcggttcg actttagcct gtattgttag cgccagtttt
    72001 taacagacgc gacgcacgaa gagcgcaata cagtccattg ctggcgggtg ttgaccgctg
    72061 acgtttcgta cgtcattaaa cattatgccg ctaaaggaag aattgaacca aatcataaaa
    72121 tcgattcagc tttggctttt cctgtaacga ttaatttcgc gcatcaaaat aattagtctg
    72181 gttaaatacc agttccgaca ggctgaatca atgccaggag gggcgaaagt ttgaagcagg
    72241 ccacaaaaaa gcacctgaaa aggtgctttt ttacgcattt ttaacaagct ggcattactg
    72301 ttgcaattct ttctcagtga agagatcggc aaacaatgcg gtgcttaaat aacgctcacc
    72361 cgatgatggt agaataacca caatattctt gttggtaaag ctttcatctt cttgtagttt
    72421 caacgccgcg gcaacagctg ctccagaaga gatacctgca agaatacctt cttcttccat
    72481 cagacgacgg gcggtagaaa tggcttcttc attggtgatg ccaatgactt tatcgaccag
    72541 cttgagatcg aggttagccg ggataaaacc tgcgccaata ccctgaattt tatgcgggcc
    72601 aggtttaatc tcttcaccag ccagtgcctg ggcgataact ggagaatcgg ttggctcaac
    72661 ggcgacagag ataagatcgg tcttgccttt ggtgccttta atgtagcggc tgacgccagt
    72721 cagcgtaccg ccagtcccaa cgccagcaat aaatacatca acctgaccgt cggtatcttc
    72781 ccagatctcc ggaccggtgg ttttttcgtg aatttcaggg tttgccggat tgctgaattg
    72841 ttgcagcagc aggtatttct ctggattgct ggcgacaatt tcttctgctt tttggattgc
    72901 gcctttcatg cctttagcac cttcggtcag caccaggttt gcacctaacg ctttcagcag
    72961 cttgcggcgt tcaatactca tggtttctgg catggtcagg gtaagtttgt aaccgcgagc
    73021 ggcagcgaca taggccagtg caatcccggt attaccgctg gttggttcaa ccagttcaac
    73081 gcctggtttc agcacgccgc gcttttcggc atcccaaatc atgttagcac cgatacggca
    73141 cttaacgctg aagctggggt tacgagattc caccttcgcc agaatgcgtc cgttaccgat
    73201 gcgattcagg cgaaccagcg gcgtgtgacc gatagtcagc gagttatctt caaaaatctt
    73261 actcatggcc tgtccttaac tgtatgaaat tgggatacaa caggtagcat acccgctcag
    73321 agaatatgcg gaagtaagga tttagcatat ctatatgcag aagggaaata atgacatgca
    73381 agatggaata aggggcggca taagccaccc ctgtttcaca caagcggttt acaaaataac
    73441 cggtagattg ttaccgccac atcgcgtgtt tatcgcgata gcaatcgacc cacatcgccg
    73501 tcgcaccaca aacggcaacg ggcatgatga acagattaag cagcgggatc atcgtaaaca
    73561 ggctggttaa agcaccaaac tgcatattgg tgattttgcg tgtgcgcagg gcggtgcgca
    73621 tctctttaaa cggcactttg tggttatcga aggggtaatc gcaatactgg atggctaaca
    73681 tccaggcgct aaacaggaac cacagtaccg gcgcgacggt ttgcccaata ccagggatga
    73741 agtaaagaat tagtaataca attgcgcgcg gcagatacca ggcaaatttt tgccattcgc
    73801 gtttcatgat tcgcggcaca tctttcatga taccgaaaat cccggtatct ggcggtgtag
    73861 cgccagtcaa tcgtgcttcc agttgttcag ccaataaacc attgaacgga gcggcaatcc
    73921 agttagcaat cgttgagaag aaatagccaa acactaacag cacagagatg actgccagag
    73981 gccacaacag atagctcagc cattgtaacc agtccggaac ataactcatg agagtcggga
    74041 tccagacatc gagttgcgta aatagccacc agaatgcgcc ccccatcaac aaaatattga
    74101 ccagcagcgg taaaataacg aaacgccgaa tcccaggttg cgagacgagc ttccagcctt
    74161 gcgcaaaata gtaaaaaccg ctgcgtgggg cagatgtgaa tgatgaaacc ataatcagga
    74221 tgagctcctt ttgaccaatc ccaggaaaat tctgcgtatt ttaccgggta attgcgcaat
    74281 ggacagttag gatatgttcg aaaaaacagc aaaaagcacg atttcatcta tctttgtgct
    74341 gtgaaagtta atagtgcact tgcacttgag gtaatcggca aatactctta gtgagtaaat
    74401 gtttgccgtg gtggcaaggt gttagaacaa cagagaatat aatgatgcag gatttgcgtc
    74461 tgatattaat cattgttggc gcgatcgcca taatcgcttt actggtacat ggtttctgga
    74521 ccagccgtaa agaacgatct tctatgttcc gcgatcggcc attaaaacga atgaagtcaa
    74581 aacgtgacga cgattcttat gacgaggatg tcgaagatga tgagggcgtt ggtgaggttc
    74641 gtgttcaccg cgtgaatcat gccccggcta acgcccagga gcatgaggct gctcgtccgt
    74701 cgccgcaaca ccagtaccaa ccgccttatg cgtctgcgca gccgcgtcaa ccggtccagc
    74761 agccgcctga agcgcaggta ccgccgcaac atgctccgcg tccagcgcag ccggtgcagc
    74821 aacccgtgca gcagcctgcc tatcagccgc agcctgaaca gccgttgcag cagccagttt
    74881 cgccacaggt cgcgtcagcg ccgcagccag tgcattcagc accgcaaccg gcacaacagg
    74941 ctttccagtc tgcagaaccc gtagcggcac cacagcctga gcctgtagcg gaaccggctc
    75001 cagttatgga taaaccgaag cgcaaagaag cggtgattat catgaacgtc gcggcgcatc
    75061 acggtagcga gctaaacggt gaactgcttc ttaacagcat tcaacaagcg ggcttcattt
    75121 ttggcgatat gaatatttac catcgtcatc ttagcccgga tggcagcggc ccggcgttat
    75181 tcagcctggc gaatatggtg aaaccgggaa cctttgatcc tgaaatgaag gatttcacta
    75241 ctccgggtgt cactatcttt atgcaggtac cgtcttacgg tgacgagctg cagaacttca
    75301 agctgatgct gcaatctgcg cagcatattg ccgatgaagt gggcggtgta gtgcttgacg
    75361 atcagcgccg tatgatgact ccgcagaaat tgcgcgagta ccaggacatc atccgcgaag
    75421 tcaaagacgc caacgcctga tacacttaag gcaaattaac tcctcttcga acccccgctt
    75481 gtcgggggtt tttagcattg atggtgcgat atggaatcaa tcgaacaaca actgacagaa
    75541 ctgcgaacga cgcttcgcca tcatgaatac ctttatcatg tgatggatgc gccggaaatt
    75601 cccgacgctg aatatgacag gctgatgcgc gaactgcgcg agctggaaac caaacatcca
    75661 gaactgatta cgcctgattc gcctacccaa cgtgtaggtg ctgcgccgct ggcggctttc
    75721 agccagatcc gccatgaagt accaatgttg tcgctggata acgtttttga tgaagaaagc
    75781 tttcttgctt tcaacaaacg tgtgcaggac cgtctgaaaa gcaacgagaa agtcacctgg
    75841 tgctgtgagc tgaagctgga tggccttgct gtcagtattc tgtatgaaaa tggcgtttta
    75901 gtcagtgccg cgactcgtgg cgatggcacc accggggaag atatcacgtc taatgtgcgt
    75961 actattcgcg ccattccgct gaagctgcac ggagagaata tcccggcgcg tctggaagta
    76021 cgtggtgaag tgttcctgcc acaggcgggc ttcgaaaaga ttaacgaaga tgcgcgacgt
    76081 acgggcggga aagtgtttgc taacccacgt aatgcggcag ctggttcact gcgtcagctt
    76141 gatccgcgta ttacagcgaa gcgaccgctc acttttttct gctatggcgt cggtgttctg
    76201 gaaggtggtg agctgccgga tactcatctt ggacgtttac tgcaatttaa aaagtggggt
    76261 ttgccggtca gcgaccgggt aacgctttgt gaatcggcgg aagaagtgct ggcgttctat
    76321 cacaaagtgg aagaagaccg cccgacgctg ggctttgata tcgacggcgt ggtgattaag
    76381 gtcaactcac tgacacagca ggagcagctt ggctttgtcg cgcgtgcccc gcgttgggcg
    76441 gtagcgttta aattcccggc gcaggaacag atgacctttg tgcgtgacgt cgagtttcag
    76501 gttgggcgta ctggcgcgat tacgcctgtt gcgcgtctgg aacctgtcca tgttgctggc
    76561 gtgctggtga gtaacgcaac cttacacaat gcggatgaaa tcgaacgtct tggtttacgc
    76621 attggcgata aagtggtgat tcgccgcgca ggcgacgtga tcccgcaggt ggtgaacgtc
    76681 gtgctttctg aacgcccgga agatacccgt gaggttgtat tcccgacgca ttgtccggta
    76741 tgtggttctg acgtcgagcg tgtggaaggt gaagcggttg cccgctgtac cggtggcctg
    76801 atttgcggtg cgcagcgtaa agagtcgctg aaacactttg tttcccgccg tgcgatggac
    76861 gttgacggta tgggcgacaa aatcatcgat cagctggttg aaaaagaata tgtccacact
    76921 ccggcggatc tgttcaaact caccgcaggc aaacttaccg gactggagcg tatggggcca
    76981 aaatcggcac aaaacgtggt taacgcgctg gaaaaagcga aagaaaccac ctttgctcgc
    77041 ttcctctatg cacttggcat ccgtgaagtc ggcgaggcca ccgcagcagg tctggcggca
    77101 tatttcggca cgctggaagc gctggaagcc gcttcgattg aagagctgca aaaggtgcct
    77161 gatgttggaa ttgtcgttgc ctcccacgtt cacaacttct ttgccgaaga aagcaaccgc
    77221 aatgtcatca gcgagctgtt ggcggaaggt gttcactggc ctgagccgat cattatcaac
    77281 gcggaagaga ttgacagccc gtttgctggt aaaaccgtgg tgcttacggg cagcttaagc
    77341 cagatgtcgc gtgatgacgc taaagctcga ctggtcgaac tgggcgcgaa agtcgcgggc
    77401 agcgtgtcga agaaaaccga tctggtgata gcgggtgaag ctgcaggatc taaactggcg
    77461 aaagcgcagg aactgggcat agaagttatc gacgaagcgg aaatgctgcg tttgctgggt
    77521 agctgagatg gaaaaagagc agctgattga aatagccaat acgataatgc cgtttggcaa
    77581 atacaaaggg cgtcgcttaa tcgacctgcc ggaggagtat cttctgtggt ttgcccgcaa
    77641 agatgagttc ccggcaggga agctcggtga gctaatgcaa atcacgctgc tgattaaaac
    77701 tgaggggctg acgcaactgg tccagcccct gaagcgtcct ctttaagctt tattggcgcg
    77761 gctttcctgc tgcgcctgta actgttcggt ctggtgtttg tatcgacgcg ccagcaccgc
    77821 acagaccatc aattggatct gatggaaaat catcagaggc agcaccatca taccgatcac
    77881 cgatgtgggg aacagaatgt ttgccatcgg gatgccattt gccagactct ttttcgaacc
    77941 acaaaagacg atagtaattt catctgcctt attgaagccc agtcggcgtg ccataaagac
    78001 gttaactaca atcacgatag ccagaagaac gcagctgacc accacgataa acagcaatga
    78061 tccccagcca actttatgcc agataccatt aacgacggct tcgctgaacg ctgtataaac
    78121 caccaacaga atggacgtct ggtcagtttt cgcaatccat tttttattgc gcgacaccca
    78181 gtcaccaatc cacggccggg aaagatgccc caatacaaac ggcagcagca attgcagcat
    78241 aattttaccg acctgctcaa ggctgcctcc cgcaccgtga acattcatca ccagaccaac
    78301 cagcaatggt gaaaggaaaa tccccaacag gctggatgct gacgcagaac aaaccgctgc
    78361 cgcgacgtta ccgcccgcca ttgaagtaaa ggcgattgca gactgcacgg tagcggggag
    78421 aatgcacaag tagagaaaac cggagtagag catcgggtcg acatttaccg gtttccacca
    78481 ggcaaacagc acgcccagaa tcggaaacag tacaaaggtg ctgcacatta cccacaaatg
    78541 cagtcgccag tgaccaccgc cagcaataat cgcttcacgt gacaacttcg cgccgtgcat
    78601 aaagaacagc agggcaatag ctgcggtggt cagattttca aagaagggga cgaaatcgcc
    78661 tctggccgga aagaaagagg ccagcaacac caccgtgatc agggttaagg tgaaaggatc
    78721 gaggatacga aaaagtttca taaagactcc agatgatcga tggttctatt gtgcttcttc
    78781 cagtttgaga aataaaattg atttattgca tccattcatg aagaaaacag atgaattatt
    78841 ctttaaagca attaaaggtt ttcgtcacag tagcgcagga gaaaagtttt agtcgtgcag
    78901 gagagcgtat cggcctgagt cagtcggcag taagtcacag tgtgaaggag ctggaaaatc
    78961 atactggtgt tcgcctgctg gacagaacca cgcgtgaagt ggtgcttaca gatgcagggc
    79021 agcagttggc tttgcgtctt gagcgactgc tggatgaact taacagcacg ttgcgcgata
    79081 ccgggcgtat ggggcaacaa ctgagcggaa aagttcgggt cgctgccagc cagaccattt
    79141 ccgcgcatct tattccgcaa tgcattgctg aaagccatcg ccgctatcca gatattcagt
    79201 ttgtcctgca cgatcgtccg cagcagtggg tgatggaaag tattcgccag ggagatgtcg
    79261 attttggcat cgtcatcgat ccaggcccag tgagcgatct gcaatgtgaa gcgattcttt
    79321 ccgagccttt cttcttgctt tgccatcgcg atagcgcttt ggccgcggaa gattatgtac
    79381 cctggcaggc attacaggga gcgaaattgg tgttgcagga ttacgcgtca ggcagccgac
    79441 cgctgattga cgcagctctg gcgcgcaacg gtattcaggc gaatattgtg caggagattg
    79501 gtcatccggc gacgctgttc ccgatggtag ccgcaggcat cggcatcagt attcttcccg
    79561 cactggcgct accattgcct gaaggtagcc cgctggtggt aaagcgcatt acgccggtgg
    79621 tggaacgcca gttgatgctg gtgcgcagga agaaccgttc actttccacc gccgcacaag
    79681 cgttatggga cgtggtacga ggccagggcc gtgcgctaat ggctgggcgg gaaggggatc
    79741 ctttgtatca gatatagagt gaattcatac tgccgggagc cccggcagta atcaatcaga
    79801 agttaaattt gatggagtag attatcgcat cctggtaaaa atcttcgccc agtttgtcat
    79861 ccgcataacg atactgaatc cctgtggtga tgtgtgaagt tgcattccac caaagtgcga
    79921 cggcaccgtt cagaccttct ttgccgccat tacctgccgc gtaggtggca tcacgatcaa
    79981 actcgtactc gttccagttg gtgagggtga atttctcact gcccagcata aagctgtaac
    80041 ctgcaaccca accggcgaca taaccgttat cgccggtata ataggtttgg tctgtatagc
    80101 gttttgcaaa gaacggtttg aaccaccaac cgctgccggt gaaattgtag ccgataccgt
    80161 acaggaacat atcgtcgtgg aaattcacgc gattcgcaga accgtaggtg ccatacgcat
    80221 gcaagtagaa attaaatccg gtgtcaccca ggtaaatacg gttggtattt ttaaaggtat
    80281 aacgctgctc gctacctggt ttattatggc gaccgttata gaagttttcc cagtcgaaga
    80341 acccgtacat ttctccccaa ctaaagttag cgccaccttc aaattcaaga taaccaaaat
    80401 catctttgtg tgatttggtc gacgattttt cggtagtccg gctggtccag tccagataat
    80461 gcacgccgat atctgcaaaa ccgcctttaa attctgcatg agatactgct ggtatcgcca
    80521 atacagaaga gagtgtcaga gtaaaaagat gttttttcat agcataattc cctatgccga
    80581 tcgttattag ttgattgctt aataaaaagg ttgattaaaa gcggcatatt gttaatgcaa
    80641 tggaaaggag agtaccaata
//
LOCUS       DACAOP010000008        76204 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.008, whole genome shotgun sequence.
ACCESSION   DACAOP010000008 DACAOP010000000
VERSION     DACAOP010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 76204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76204
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.008"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..865)
                     /locus_tag="IT892_000605"
     CDS             complement(<1..865)
                     /locus_tag="IT892_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP3133848.1"
                     /translation="MRAPVKDIKIVSKSIDFIELMELGMIKGIGLQNFRSFVNKTFID
                     LKPITVFVGKNSSGKSSLLRTFPLLRQSVEENTTGPILWYGRYVDFGDFTDVLSRKSE
                     KKEITFSFSLSIPPEVSQRYTYYRSTDLAKQPTDIEAELTVYSKDKKTKTKTIKLILA
                     DLTIFISMDESSNVKLLIESDDKTIERDGIIAKNLGQFIPNLILKGKEDSPPPSTSFY
                     LRHSRHDRALELSFIDSAAKYIKKYFHTKSDINQVTEAFKRIGFIPKAYASKLVAFLF
                     KEQKVFSRNFEF"
     gene            complement(1166..1390)
                     /locus_tag="IT892_000606"
     CDS             complement(1166..1390)
                     /locus_tag="IT892_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133849.1"
                     /translation="MMPVPPIHSTQNIKLMAVVHRLQQIMINENLTPDELVGCAGVVR
                     DNHRKYSDISNPKIEAFRPPNMAKPPPRRP"
     gene            complement(1407..1865)
                     /locus_tag="IT892_000607"
     CDS             complement(1407..1865)
                     /locus_tag="IT892_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HAP3133850.1"
                     /translation="MSKIHELKIAPEYFNSVISQEKRAEFRLNDRDYSSGDILGLHEW
                     EPVNRYTGKRVSVRVTNVTDLSEWAENYVMLSFQLMMPDVQCGMSLMNWKELSEKGLV
                     FRVNHEILHPLGLAIRYETLNSVSGRAYIADDGVWQYSDKLVADAKKMGG"
     gene            complement(1865..4156)
                     /locus_tag="IT892_000608"
     CDS             complement(1865..4156)
                     /locus_tag="IT892_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HAP3133851.1"
                     /translation="MAVETRGRIAPSLALPISKRTGDTFVGAYPWNAPRAAIGRDRPL
                     TRAEFRQVQGVLYRIDRLPFFLKTLFTSRYNFIRRTKSPLGALYFLKNTFERKLLPRL
                     ERVNELCGMNESASIGFLSERDEYARLPDMNDKELKKFAARIAAQLWRKYEELSDEWA
                     EAFGGKETLFTDEAQVHIYGQVAGVARAFNLTPLYWKKYRKGQITIRMAFSAISRLIK
                     DDWWVNQLKAQRMRWREALLIAAGEVNKDRSPYASKMAIREVHSRRLANLEYLKSCEL
                     ENKVTGERIDLISKVMGSISNPEIRRMELMNTIAGIERYAASVGDVGMFITLTTPSKY
                     HPTRQVGKGDSKTVQLNHGWNETAFTPKNGQRYLCRIWSLMRTAFKDNDLEVYGMRVV
                     EPHHDGTPHWHMMLFCKLSQRKAINEIMRRYALKEDGHEKGAAKQRFESRHLNQGGAA
                     GYIAKYIAKNIDGYALDGQLDHDTGKSLKDTAAAVTAWASTWRIPQFKPIGLPTMGAY
                     RELRKLPRGVSIASEFDDRVEAVRAAADEGEFDLYISAQGGANMQRDAQAVRVARKVT
                     DEVNEYEEDIEKVVGIYAPHLGVSRVHVTRTAEWRIVPKVLAVEPLTLKSGFAAPRSP
                     VNNCGKLADGGDPVMTPTPSEQAAAVLNLIEAGVIGWNEPDVMKVLNGALKAGAPRNN
                     RQQRSNAPLKTSEQAPSARMTKPERDRVAKIRFDLAQEGITPERWALEALARGATVIY
                     GDKKIKYAAADEWPGFSIQEEQN"
     gene            complement(4146..4421)
                     /locus_tag="IT892_000609"
     CDS             complement(4146..4421)
                     /locus_tag="IT892_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133852.1"
                     /translation="MSIRIEINHQYVVTSDRYQFILQEKKVATAGKNKGSEWLDTVGY
                     YPTIQKLISGLVLHDLLNGGADSFAALGEQVEQLGLQCQTAFCADGR"
     gene            complement(4444..4662)
                     /locus_tag="IT892_000610"
     CDS             complement(4444..4662)
                     /locus_tag="IT892_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000549519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2732 family protein"
                     /protein_id="HAP3133853.1"
                     /translation="MHKQNKVPTCVLSVHLAQALRDAQLDTATRLSSHFDRLIAHISK
                     LELNRTEIIELLGQESEKLHNSIFHCAC"
     gene            complement(4729..5229)
                     /locus_tag="IT892_000611"
     CDS             complement(4729..5229)
                     /locus_tag="IT892_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017441883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein B"
                     /protein_id="HAP3133854.1"
                     /translation="MTVMTLALVQKQPAALRVVIGKHLAEPRWHDTCDFYNQMMERDR
                     LTVCFHARLKQRHAVMHFEEMNDVDRERLACAIDELRAAFSKRRQVGASESAYISFLT
                     VGQRRSLFLHAGLSEVEFNQPYWRIDEDACYWREKLFRALRELFGLFEHAPTILTSVK
                     PEQYLH"
     gene            complement(5407..5682)
                     /locus_tag="IT892_000612"
     CDS             complement(5407..5682)
                     /locus_tag="IT892_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133855.1"
                     /translation="MNRVIESASDAVPYQEFARLIGKTPAAVKGMIEKGKLPIVEMTD
                     PQSTSGRAGEYWVYLPAWNKGMKMAYDSRPKEIRDGWLMWLGLGEPA"
     gene            5818..6114
                     /locus_tag="IT892_000613"
     CDS             5818..6114
                     /locus_tag="IT892_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP3133856.1"
                     /translation="MIPVNEKLAIMRESERMNRKEFSDLTGVPYSSLSSYEKGVKDMG
                     IQAVMKILNHPQFKKYTMWFMTETISPEAGQIAPALAHFGQQTTTSPHSDQKTG"
     gene            6211..7224
                     /locus_tag="IT892_000614"
     CDS             6211..7224
                     /locus_tag="IT892_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP3133857.1"
                     /translation="MSVKKLDDGRYEVDIRPAGRNGKRIRRKFDKKSEAIAFEKHTQY
                     NHHNKEWLAKPTDKRHLSELTKIWWELKGKYETHGRDYLGKLELFTKITSDPCAFQIT
                     KSLISQYSTVRRSQGIKPSSINRDLTCLSGMFTALIDAELFFGEHPFRGLKRLKEDKP
                     ETGYLTQEEIALLLSKVDGDNKKIAILCLSTGARWSEAAKLKAENIIQNRVTFVKTKT
                     NKPRTVPISEELATMITTGKRGYLFTDANYPAFRRLMKELKPDLPPGQATHALRHSFA
                     THFMINGGNIITLQRILGHSRIEQTMTYAHFAPEYLQDAITLNPLRGGVGSQSVHTVS
                     TVG"
     gene            complement(7490..7807)
                     /locus_tag="IT892_000615"
     CDS             complement(7490..7807)
                     /locus_tag="IT892_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133858.1"
                     /translation="MKKIAAISLISIFIMSGCAVHNDETSIGKFGLAYKSNIQRKLDN
                     QYYTEAEASLARGRISGAENIVKNDATHFCVTQGKKMQIVELKTEGVGLHGVARLTFK
                     CGE"
     gene            8213..9112
                     /gene="yegS"
                     /locus_tag="IT892_000616"
     CDS             8213..9112
                     /gene="yegS"
                     /locus_tag="IT892_000616"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid kinase YegS"
                     /protein_id="HAP3133859.1"
                     /translation="MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKG
                     DAARYVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATS
                     VGIPEALDKALKLAIAGDAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALG
                     SVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALIND
                     GLLQLRIFTGDEILPALVSTLKSDEDNPNIIEGASSWFDIQAPHDITFNLDGEPLSGQ
                     NFHIEILPAALRCRLPPDCPLLR"
     gene            complement(9194..9973)
                     /locus_tag="IT892_000617"
     CDS             complement(9194..9973)
                     /locus_tag="IT892_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP3133860.1"
                     /translation="MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRF
                     LEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMT
                     VILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMH
                     GSIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKF
                     NRRGFNQVLPIEKIDIIITDDAVSEVDKLALQKTRVKLITV"
     gene            complement(10073..11113)
                     /gene="gatD"
                     /locus_tag="IT892_000618"
     CDS             complement(10073..11113)
                     /gene="gatD"
                     /locus_tag="IT892_000618"
                     /EC_number="1.1.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAP3133861.1"
                     /translation="MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR
                     IFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQ
                     CAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCE
                     NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP
                     QMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKI
                     LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIA
                     RNAMPGKVLLIP"
     gene            complement(11161..12516)
                     /locus_tag="IT892_000619"
     CDS             complement(11161..12516)
                     /locus_tag="IT892_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol permease IIC component"
                     /protein_id="HAP3133862.1"
                     /translation="MFSEVMRYILDLGPTVMLPIVIIIFSKILGMKAGDCFKAGLHIG
                     IGFVGIGLVIGLMLDSIGPAAKAMAENFDLNLHVVDVGWPGSSPMTWASQIALVAIPI
                     AILVNVAMLLTRMTRVVNVDIWNIWHMTFTGALLHLATGSWMIGMAGVVIHAAFVYKL
                     GDWFARDTRNFFELEGIAIPHGTSAYMGPIAVLVDAIIEKIPGVNRIKFSADDIQRKF
                     GPFGEPVTVGFVMGLIIGILAGYDVKGVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAK
                     QARSRLQAKFGGQEFLIGLDPALLLGHTAVVSASLIFIPLTILIAVCVPGNQVLPFGD
                     LATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQTIGLHTQLAANAGALKAGG
                     MVASMDQGGSPITWLLIQVFSPQNIPGFIIIGAIYLTGIFMTWRRARGFIKQEKVVLA
                     E"
     gene            complement(12520..12804)
                     /gene="gatB"
                     /locus_tag="IT892_000620"
     CDS             complement(12520..12804)
                     /gene="gatB"
                     /locus_tag="IT892_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIB"
                     /protein_id="HAP3133863.1"
                     /translation="MKRKIIVACGGAVATSTMAAEEIKELCQNHNIPVELIQCRVNEI
                     ETYMDGVHLICTTAKVDRSFGDIPLVHGMPFISGIGIEALQNKILTILQG"
     gene            complement(12835..13287)
                     /gene="gatA"
                     /locus_tag="IT892_000621"
     CDS             complement(12835..13287)
                     /gene="gatA"
                     /locus_tag="IT892_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIA"
                     /protein_id="HAP3133864.1"
                     /translation="MTNLFVRSGISFVDRSEVLTHIGNEMLAKGVVHDTWPQALIARE
                     AEFPTGIMLEQHAIAIPHCEAIHAKSSAIYLLRPTNKVHFQQADDDNDVAVSLVIALI
                     VENPQQQLKLLRCLFGKLQQPDIVETLITLPETQLKEYFTKYVLDSDE"
     gene            complement(13297..14559)
                     /gene="gatZ"
                     /locus_tag="IT892_000622"
     CDS             complement(13297..14559)
                     /gene="gatZ"
                     /locus_tag="IT892_000622"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatZ"
                     /protein_id="HAP3133865.1"
                     /translation="MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIE
                     ATSNQVNQFGGYTGMTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENADAA
                     MEKSVELVKEYVRAGFSKIHLDASMSCAGDPIPLAPETVVERAAVLCFAAESVATDCQ
                     REQLSYVIGTEVPVPGGEASAIQSVHITHVEDAANTLRTHQKAFIARGLTEALTRVIA
                     IVVQPGVEFEHSNIIHYQPQEAQPLAQWIENTRMVYEAHSTDYQTRTAYWELVRDHFA
                     ILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVMLDEPQYWKKYYRTGF
                     NDSLLDIRYSLSDRIRYYWPHSRIKNSVDTMMVNLEGVDIPLGMISQYLPKQFERIQS
                     GELSAIPHQLIMDKIYDVLRAYRYGCAE"
     gene            complement(14588..15442)
                     /gene="gatY"
                     /locus_tag="IT892_000623"
     CDS             complement(14588..15442)
                     /gene="gatY"
                     /locus_tag="IT892_000623"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416599.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HAP3133866.1"
                     /translation="MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAP
                     VIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVM
                     IDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQA
                     REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDI
                     QQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIA
                     DCGCEGRA"
     gene            complement(15750..16802)
                     /gene="fbaB"
                     /locus_tag="IT892_000624"
     CDS             complement(15750..16802)
                     /gene="fbaB"
                     /locus_tag="IT892_000624"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HAP3133867.1"
                     /translation="MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNN
                     RPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAI
                     EAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMG
                     AVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSA
                     DLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQL
                     ANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKL
                     INAVQDVYLDSKITIA"
     gene            17059..18336
                     /locus_tag="IT892_000625"
     CDS             17059..18336
                     /locus_tag="IT892_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease"
                     /protein_id="HAP3133868.1"
                     /translation="MKTTAKLSFMMFVEWFIWGAWFVPLWLWLSKSGFSAGEIGWSYA
                     CTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGALLMYFAAQQTTFAGFFPLLLAYS
                     LTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQILGYADISPT
                     NIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILLRDKNFLVFFFCS
                     FLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLL
                     LGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGVSYDFYYVTAYIYVDKKAPVHMR
                     TAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVNGLTFNWSGMWTFGAVMIAII
                     AVLFMIFFRESDNEITAIKVDDRDIALTQGEVK"
     gene            18333..19337
                     /locus_tag="IT892_000626"
     CDS             18333..19337
                     /locus_tag="IT892_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HAP3133869.1"
                     /translation="MKTERILGALYGQALGDAMGMPSELWPRSRVKAHFGWIDRFLPG
                     PKENNAACYFNRAEFTDDTSMALCLADALLEREGKIDPNLIGRNILDWALRFDAFNKN
                     VLGPTSKIALNAIRDGKPIAELENNGVTNGAAMRVSPLGCLLPAHDVDSFIDDVALAS
                     SPTHKSDLAVAGAVVIAWAISRAIDGESWSAIVDSLPSIARHAQQKRITTFSASLAAR
                     LEIALKIVRNADGTESASEQLYQVVGAGTSTIESVPCAIALVELAQTDPNRCAVLCAN
                     LGGDTDTIGAMATAICGALHGVNAIDPALKAELDAVNQLDFNRYATALAKYRQQREAV
                     "
     gene            19334..20299
                     /locus_tag="IT892_000627"
     CDS             19334..20299
                     /locus_tag="IT892_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAP3133870.1"
                     /translation="MSGARLHTLLPELTSRQPVMVVGAAVIDVIADAYALPWRGCDIE
                     LKQQSVNVGGCALNIAVALKRLGIEAGNALPLGQGVWAEIIRNRMAKEGLISLIDNAE
                     GDNGWCLALVEPDGERTFMSFSGVENQWNRQWLARLTVAPGSLLYFSGYQLASPCGEL
                     LVEWLEKLQDVTPFIDFGPRIGDIPDALLARIMACRPLVSLNRQEAEIAAERFALSAE
                     ITTLGKQWQEKFAAPLIVRLDKEGAWYFSNDASGCIPAFPTQVVDTIGAGDSHAGGVL
                     AGLASGLPLADAVLLGNAVASWVVGHRGGDCAPTREELLLAHKNV"
     gene            complement(20273..21019)
                     /locus_tag="IT892_000628"
     CDS             complement(20273..21019)
                     /locus_tag="IT892_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP3133871.1"
                     /translation="MEQAHTQLITQLNERILAADNTPLYIKFAETVKNAVRSGVLEHG
                     NILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRSRGYGTQINNIFEYSLKEARGFS
                     QQVVLRGKKPDTLWVNKRVVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
                     VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVI
                     KQVALDQQQRPIEYSISHCRSDLYVFVCEE"
     gene            complement(21071..21889)
                     /locus_tag="IT892_000629"
     CDS             complement(21071..21889)
                     /locus_tag="IT892_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 25 family protein"
                     /protein_id="HAP3133872.1"
                     /translation="MQLRITSRKKLTSLLCALGLISIVAIYPRQTVNFFYSTAVQITD
                     YIHFYGYRPVKSFAIRIPASYTIHGIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKAT
                     EGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVAAPVQARLFLQTVDFSQGDFPAVL
                     DVEERGKLSAKELRKRVSQWLKMVEKSTGKKPIIYSGAVFYHTNLAGYFNEYPWWVAH
                     YYQRRPDNDGMAWRFWQHSDRGQVDGINGPVDFNVFNGTVEELQGFVDGIKETP"
     gene            complement(21954..22754)
                     /gene="thiD"
                     /locus_tag="IT892_000630"
     CDS             complement(21954..22754)
                     /gene="thiD"
                     /locus_tag="IT892_000630"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAP3133873.1"
                     /translation="MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQ
                     NTRGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRYQIQNV
                     VLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAPHARTEQEMLE
                     QGRSLLAMGCGAVLMKGGHLDDEQSPDWLFTREGEQRFTAPRIMTKNTHGTGCTLSAA
                     LAALRPRHTNWADTVQEAKSWLSSALAQADTLEVGHGIGPVHHFHAWW"
     gene            complement(22751..23539)
                     /gene="thiM"
                     /locus_tag="IT892_000631"
     CDS             complement(22751..23539)
                     /gene="thiM"
                     /locus_tag="IT892_000631"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HAP3133874.1"
                     /translation="MQVDLLGSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLAL
                     GASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKSSQTPWTLDPVA
                     VGALDYRRHFCHELLSFKPAAIRGNASEIMALAGIANGGRGVDTTDAAANAIPAAQTL
                     ARETGAIVVVTGEMDYVTDGHRIIGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTL
                     ENVASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA"
     regulatory      complement(23574..23670)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(23762..24034)
                     /gene="rcnR"
                     /locus_tag="IT892_000632"
     CDS             complement(23762..24034)
                     /gene="rcnR"
                     /locus_tag="IT892_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II)-binding transcriptional repressor
                     RcnR"
                     /protein_id="HAP3133875.1"
                     /translation="MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAA
                     IRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK"
     gene            24155..24979
                     /locus_tag="IT892_000633"
     CDS             24155..24979
                     /locus_tag="IT892_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt efflux protein RcnA"
                     /protein_id="HAP3133876.1"
                     /translation="MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIA
                     IKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIISTA
                     FWMFWRTWRGERNWLENMHGHDYEHHHHDHEHHHDHGHHHHHEHGEYQDAHARAHAND
                     IKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSIGLA
                     LTLVTVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR"
     gene            25198..25536
                     /gene="rcnB"
                     /locus_tag="IT892_000634"
     CDS             25198..25536
                     /gene="rcnB"
                     /locus_tag="IT892_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416610.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II) efflux transporter accessory
                     subunit RcnB"
                     /protein_id="HAP3133877.1"
                     /translation="MTIKNKMLLGALLLVTSAAWAAPATAGSTNTSGISKYELSSFIA
                     DFKHFKPGDTVPEMYRTDDYNIKQWQLRNLPAPDAGTHWTYMGGAYVLISDTDGKIIK
                     AYDGEIFYHR"
     gene            complement(25618..26652)
                     /locus_tag="IT892_000635"
     CDS             complement(25618..26652)
                     /locus_tag="IT892_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="HAP3133878.1"
                     /translation="MEIRIMLFILMMMVMPVSYAACYSELSVQHNLVVQGDFALTQTQ
                     MATYEHNFNDSSCVSTNTITPMSPSDIIVGLYNDTIKLNLHFEWTNKNNITLSNNQTS
                     FTSGYSVTVTPAASNAKVNVSAGGGGSVMINGVATLSSASSSTRGSAAVQFLLCLLGG
                     KSWDACVNSYRNALAQNAGVYSFNLTLSYNPITTTCKPDDLLITLDSIPVSQLPATGN
                     KATINSKQGDIILRCKNLLGQQNQTSRKMQVYLSSSDLLTNSNTILKGAEDNGVGFIL
                     ESNGSPVTLLNITNSSKGYTNLKEVAAKSKLTDTTVSIPITASYYVYDTNKVKSGALE
                     ATALINVKYD"
     gene            complement(26668..29148)
                     /locus_tag="IT892_000636"
     CDS             complement(26668..29148)
                     /locus_tag="IT892_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HAP3133879.1"
                     /translation="MLRMTPLASAIVALLLGIEAYAAEETFDTHFMIGGMKDQQVANI
                     RLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNPQETCLSREVIKRLGINSDNFASGK
                     QCLTFEQLVQGGSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYL
                     SQYYSDYKALGNNKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGVWKSNTLYLERGF
                     AQLLGTLRVGDMYTSSDIFDSVRFRGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVT
                     IEQNGFVVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQ
                     PGVSKYDLAAGRSHIEGASKQSDFVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGAGW
                     NTRIGAISVDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRT
                     FNDHVWANNKDNYRRDENDVYDIADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLW
                     RDYWGRSGSSKDYQLSYSNNLRRISYTLAASQAYDENHHEEKRFNIFISIPFDWGDDV
                     STPRRQIYMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSHQHQGNETTAGANL
                     TWNAPVATVNGSYSQSSTYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDA
                     YVNGQKYRTTNRNGVVIYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVL
                     VNFDTDQRKPWFIKALRADGQSLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVN
                     VAIDKQQGLSCTITFGKEIDESRNYICQ"
     gene            complement(29164..29838)
                     /locus_tag="IT892_000637"
     CDS             complement(29164..29838)
                     /locus_tag="IT892_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HAP3133880.1"
                     /translation="MKGLLSLLIFSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQG
                     NRSSLLQAWIDDGDTSLPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKES
                     IFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
                     LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGN
                     YISDKI"
     gene            complement(29918..30460)
                     /locus_tag="IT892_000638"
     CDS             complement(29918..30460)
                     /locus_tag="IT892_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3133881.1"
                     /translation="MKRSIIAAAVFSSFFMSAGVFAADVDTGTLTIKGNIAESPCKFE
                     AGGDSVSINMPTVPTSVFEGKAKYSTYDDAVGVTSSMLKISCPKEVAGVKLSLITNDK
                     ITGNDKAIASSNDTVGYYLYLGDNSDVLDVSAPFNIESYKTAEGQYAIPFKAKYLKLT
                     DNSVQSGDVLSSLVMRVAQD"
     gene            complement(30753..31034)
                     /locus_tag="IT892_000639"
     CDS             complement(30753..31034)
                     /locus_tag="IT892_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehE family protein"
                     /protein_id="HAP3133882.1"
                     /translation="MNKYWLSGIIFLAYGLASPAFSSETATLAINGRISPPTCSMAMV
                     NGQPQQHCGQLTYNVDTRHLFSSPVKGVTTEVVVAGSDSKRRIVLNRYD"
     gene            complement(31297..32406)
                     /gene="apbC"
                     /locus_tag="IT892_000640"
     CDS             complement(31297..32406)
                     /gene="apbC"
                     /locus_tag="IT892_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HAP3133883.1"
                     /translation="MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAW
                     MDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPG
                     INGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
                     RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDY
                     LVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVE
                     NMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDKGTPTVISRP
                     ESEFTAIYRQLADRVAAQLYWQGEVIPGEISFRAV"
     gene            32538..34571
                     /gene="metG"
                     /locus_tag="IT892_000641"
     CDS             32538..34571
                     /gene="metG"
                     /locus_tag="IT892_000641"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAP3133884.1"
                     /translation="MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGH
                     EVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEE
                     NRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCE
                     VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANK
                     MQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSV
                     SFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKM
                     SKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVN
                     LASRNAGFINKRFDGVLANELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALAD
                     LANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLN
                     TELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDP
                     IQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQ
                     ALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK"
     gene            34712..38506
                     /locus_tag="IT892_000642"
     CDS             34712..38506
                     /locus_tag="IT892_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WGR and DUF4132 domain-containing protein"
                     /protein_id="HAP3133885.1"
                     /translation="MRHFIYQDEKSHKFWAVEQQGNELHISWGKVGTKGQSQIKSFSD
                     AAAAEKAELKLIAEKVKKGYVEQAKDNSLQPSQTVTGSLKVADLSTIIQEQPSFVAET
                     RAPDKNTDAVLPWLAKDIAVVFPPEVVHTTLSHRRFPGVPVQQADKLTQLRRLACSVS
                     QRDNKTATFDFSACSLEWQNTVAQAISQIDGLKTTQLPSPVMAVLTALEMKCTRYKVR
                     EDVMDQIVQEVGLEYATDVIIHLQQIDIEWDYANNVIIILPSGIAPSYLEQYSRFELR
                     LRKHLSLTEESLWQKCAQKLIAAIPHIPEWRQPLIALLLPEKPEIAHEIAQRLLGQKK
                     LPSLEWLKIVATDEHILASLEKYHEPYAIFDDYYCGAIWSATVLQEQGVAALPRFAPY
                     AASDYCADVLRHINHPFALTLLIRVAGQTKRCHDRMTKAIAAFPHAAMAALTELLGQK
                     EENSWRIMLMTMLISQPALAEQVIPWLSTPAVAVLKSCQQQLTQPSNHASADLLPAVV
                     VSPPWLSKKKKSPIPVLDLAPLGIEPICYLTEEISNQLLAKYIWYSKHITVSHEESTT
                     NLLARMGFQRRIAGTYIKAPEAVVEAWLNEDYSTLLSEFKVFHSPTGHYWQLGILTTL
                     PLEKAVKAWNALTLSPHTDTEYSMLHFGLKGLPGLVNSLARYPQEALPITNYFAASEL
                     APAVARAFNKLKTLRENARSWLLKYPEHALTGLLPAALGKAGEAQDNARAALRMLTEN
                     GHQPLLQEIARRYNQPEVTDAVNALLALDPLDNHPTKIPTLPAFYQPSLWTRPVLKAN
                     AQSLPDSALLHLGEMLRFPQEEALYPGLLQVKDVCSADSLAGFAWDLFTAWQTAGAPS
                     KESWAFTALGVLGNDDTARKLTPLIRAWPGESQHKRATVGLDILAAIGSDIALMQLNG
                     IAQKLKFKALQERAKEKIADIAESRELTVAELEDRLAPDLGLDDNGSLLLDFGPRQFT
                     VSFDETLKPFVRDVSGSRLKDLPKPNKSDDETRANDAVNRYKLLKKDARTIAAQQVAR
                     LESAMCLRRRWSLENFQLFLVEHPLVRHLTRRLIWGVYSAENQLLACFRVAEDNSSST
                     ADDDLFTLPEGDISIGTPHVLEISPTDAAAFGQLFAAYELLPPFRQLDRNSYALTEAE
                     RNASELTRWAGRKCPSGRVMGLANKGWIKGEPQDGGWIGWMIKPLGRWSLIMEIDEGF
                     AVGMSPAELSAEQLLSKLWLWEGKAERYGWGSNSTQEAQFSVIDAITASELINDIEAL
                     FE"
     gene            38516..42148
                     /locus_tag="IT892_000643"
     CDS             38516..42148
                     /locus_tag="IT892_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HAP3133886.1"
                     /translation="MDKELPWLADNAQLELKYKKGKTPLSHRRWPGEPVSVITGSLIQ
                     TLGDELLQKAEKKKNIVWRYENFSLEWQSAITQAINLIGEHKPSIPARTMAALACIAQ
                     NDSQQLLDEIVQQEGLEYATEVVIARQFIARCYESDPLVVTLQYQDEDYGYGYRSETY
                     NEFDLRLRKHLSLAEESCWQRCADKLIAALPGITKVRRPFIALILPEKPEIANELVGL
                     ECPRTHFHSKEWLKVVANDPTAVRKLEHYWSQDIFSDREASYMSHENHFGYAACAALL
                     REQGLAAIPRLAMYAHKEDCGSLLVQINHPQVIRTLLLVADKNKPSLQRVAKYHKNFP
                     HATLAALAELLALTEPPARPGYPIIEDKKLPAQQKARDEYWRTLLQTLMASQPQLAAE
                     VMPWLSTQPQSVLKSYLSAPPKPVIDGTDNSNLPEILVSPPWRSKKKMTAPRLDLAPL
                     ELTPQVYWQPGEQERLAATEPARYFSTESLAQRMEQKSGRVVLQELGFGDDVWLFLNY
                     ILPGKLDAARNSLFVQWHYYQGRVEEILNGWNSPEAQLAEQALRSGHIEALINIWEND
                     NYSHYRPEKSVWNLYLLAQLPREMALTFWLRVNEKKHLFAGEDYFLSILGLDALPGLL
                     LAFSHRPKETFPLILNFGATELALPVAHVWRRFAAQRDLARQWILQWPEHTASALIPL
                     VFTKPSDNSEAALLALRLLYEQGHGELLQTVANRWQRTDVWSALEQLLKQGPMDIYPA
                     RIPKAPDFWHPAMWSRPRLITNNQPVTGDALEIIGEMLRFTQGGRFYSGLEQLKTFCQ
                     PQTLAAFAWDLFTAWQQAGAPAKDNWAFLALSLFGDESTARDLTTQILAWPQEGKSAR
                     AVSGLNILTLMNNDMALIQLHHISQRAKSRPLRDNAAEFLQVVAENRGLSQEELADRL
                     VPTLGLDDPQALSFDFGPRQFTVRFDENLNPVIFDQQNVRQKSVPRLRADDDQLKAHE
                     ALARLKGLKKDATQVSKNLLPRLEAALRTTRRWSLADFHSLFVNHPFTRLVTQRLIWG
                     GYPANEPRRLLNAFRVAAEGEFCNAQDEPIDLPADALIGIAHPLEMAVEMRSEFAQLF
                     ADYEIMPPFRQLSRRTVLLTPDESTSNSLTRWEGKSATVGQLMGMRYKGWESGYEDTF
                     VYDLGEYRLVLKFSPGFNHYNVDSKALMSCRSLRVYRDNKSVTFAELDVFDLSEALSA
                     PDVIFH"
     gene            42209..42526
                     /locus_tag="IT892_000644"
     CDS             42209..42526
                     /locus_tag="IT892_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133887.1"
                     /translation="MIVQKELVAIYDYEVPVPEDPFSFRLEIHKCSELFTGSVYRLER
                     FRLRPTFHQRDREDADPLINDALIYIRDECIDERKLRGESPETVIAIFNRELQNIFNQ
                     EIE"
     gene            42833..43921
                     /locus_tag="IT892_000645"
     CDS             42833..43921
                     /locus_tag="IT892_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416623.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAP3133888.1"
                     /translation="MSPQNNHLQRPPAAVLYADELAKLKQNDNAPCPPGWQLSLPAAR
                     AFILGDEAQNISRKVVISPSAVERMLVTLATGRGLMLVGEPGTAKSLLSELLATAISG
                     DAGLTIQGGASTTEDQIKYGWNYALLINHGPSTEALVPAPLYQGMRDGKIVRFEEITR
                     TPLEVQDCLLGMLSDRVMTVPELTGEASQLYAREGFNIIATANTRDRGVNEMSAALKR
                     RFDFETVFPIMDFAQELELVASASARLLAHSGIPHKVPDAVLELLVRTFRDLRANGEK
                     KTSMDTLTAIMSTAEAVNVAHAVGVRAWFLANRAGEPADLVECIAGTIVKDNEEDRAR
                     LRRYFEQRVVTHKEAHWQAYYQARHRLP"
     gene            43932..46211
                     /locus_tag="IT892_000646"
     CDS             43932..46211
                     /locus_tag="IT892_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133889.1"
                     /translation="MSEPLIVGIRHHSPACARLVKSLIESQRPRYVLIEGPADFNDRV
                     DELFLAHQLPVAIYSYCQYQDGAAPGRGAWTPFAEFSPEWQALQAARRIQTQTYFIDL
                     PCWAQSEEEDDSPDTQDESQALLLRATRMDNSDTLWDHLFEDESQQTALPSALAHYFA
                     QLRGDASGDALNRQREAFMARWIGWAMQQNNGDVLVVCGGWHAPALAKMWRECPQKIN
                     KPELPSLADAVTGCYLTPYSEKRLDVLAGYLSGMPAPVWQNWCWQWGLQKAGEQLLKT
                     ILTRLRQHKLPASTADMAAAHLHAMALAQLRGHTLPLRTNWLDAIAGSLIKEALNAPL
                     PWSYRGVIHPDTDPILLTLIDTLAGDGFGKLAPSTPQPPLPKDVTCELERTAISLPAE
                     LTLNRFTPDGLAQSQVLHRLAILEIPGIVRQQGSTLTLAGNGEERWKLTRPLSQHAAL
                     IEAACFGATLQEAARNKLEADMLDAGGIGSITTCLSQAALAGLASFSQQLLEQLTLLI
                     AQENQFAEMGQALEVLYALWRLDEISGMQGAQILQTTLCAAIDRTLWLCESNGRPDEK
                     EFHAHLHSWQALCHILRDLHSGVNLPGVSLSAAVALLERRSQAIHAPALDRGAALGAL
                     MRLEHPNASAEAALTMLAQLSPAQSGEALHGLLALARHQLACQPAFIAGFSSHLNQLS
                     DDDFINALPDLRAAMAWLPPRERGTLAHQVLEHYQLAQLPVSALQMPLHCPPQAIAHH
                     QQLEQQALASLQHWGVFHV"
     gene            46204..47340
                     /locus_tag="IT892_000647"
     CDS             46204..47340
                     /locus_tag="IT892_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP3133890.1"
                     /translation="MSELNDLLTTRELQRWRLILGEAAETTLCGLDDNARQIDHALEW
                     LYGRDPERLQRGERSGGLGGSNLTTPEWINSIHTLFPQQVIERLESDAVLRYGIEDVV
                     TNLDVLERMQPSESLLRAVLHTKHLMNPEVLATARRIVRQVVEEIMARLAKEVRQAFS
                     GVRDRRRRSSIPLARNFDFKSTLRANLQHWHPQHGKLYIESPRFNSRIKRQSEQWQLV
                     LLVDQSGSMVDSVIHSAVMAACLWQLPGIRTHLVAFDTSVVDLTADVADPVELLMKVQ
                     LGGGTNIASAVEYGRQLIEQPAKSVIILVSDFYEGGSSSLLTHQVKKCVQSGIKVLGL
                     AALDSTATPCYDHDTAQALVNVGAQIAAMTPGELASWLAENLQS"
     gene            47337..49337
                     /locus_tag="IT892_000648"
     CDS             47337..49337
                     /locus_tag="IT892_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HAP3133891.1"
                     /translation="MNSLRPELLELTPQALTALSNAGFVKRSLKELENGNVPEISHEN
                     GALIATFSDGVRTQLANGQALKEAQCSCGASGMCRHHVMLVLSYQRLCATAQPTGKEE
                     EWDPAIWLEELATLPDATRKRAQALVAKGITIELFCAPGEIPSARLPMSDVRFYSRSS
                     IRFARCDCIEGTLCEHVVLAVQAFVEAKTQQAEFNHLIWQMRSEHVTSSDDPFASEEG
                     KTCRQYVQQLSQALWLSGISQPLIHYEAAFSRAQQAAERCNWRWVSESLRQLRASVDA
                     FHARASHYHAGECLCQLAALNSRLNCAHEMAQRDSVGEIPPMPWRTVVGAGIAGEAKL
                     DHLRLVSLGMRCWQDIEHYGLRIWFTDPDTGSILHLSRSWPRSEQENSPAATRRLFSF
                     QAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDAWQMLSAPLRQPGIVALR
                     EYLRQRPPACIRPLNQVDNLFILPVAECISLGWDSSRQTLDAQVISGEGEDNLLTLSL
                     PASASAPYAVERMAALLQQTEDPVCLVSGFVSFVEGQLTLEPQVMMTKTRAWALDAET
                     APVAPLPSASVLPVPSTAHQLLIRCQALLIQLLHNGWRYQEQSAIGQAELLANDLTAV
                     GFYRLAHVLGQFRNTESEARVEAMNNVVLLCEQLFPMLQQQG"
     gene            49462..49923
                     /locus_tag="IT892_000649"
     CDS             49462..49923
                     /locus_tag="IT892_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416627.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HAP3133892.1"
                     /translation="MKAFNKLFSLVVASVLVFSLAGCGDKEESKKFSANLNGTEIAIT
                     YVYKGDKVLKQSSETKIQFASIGATTKEDAAKTLEPLSAKYKNIAGVEEKLTYTDTYA
                     QENVTIDMEKVDFKALQGISGINVSAEDAKKGITMAQMELVMKAAGFKEVK"
     gene            complement(49964..50434)
                     /locus_tag="IT892_000650"
     CDS             complement(49964..50434)
                     /locus_tag="IT892_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAP3133893.1"
                     /translation="MLSNDILRSVRYILKANNNDLVRILALGNVEATAEQIAVWLRKE
                     DEEGFQRCPDIVLSSFLNGLIYEKRGKDESAPALEPERRINNNIVLKKLRIAFSLKTD
                     DILAILTEQQFRVSMPEITAMMRAPDHKNFRECGDQFLRYFLRGLAARQHVKKS"
     gene            complement(50481..51200)
                     /gene="yehT"
                     /locus_tag="IT892_000651"
     CDS             complement(50481..51200)
                     /gene="yehT"
                     /locus_tag="IT892_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310963.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BtsR"
                     /protein_id="HAP3133894.1"
                     /translation="MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVH
                     KLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKP
                     IDEARLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRM
                     SGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILR
                     NGLTVPVSRRYLKSLKEAIGL"
     gene            complement(51197..52882)
                     /gene="btsS"
                     /locus_tag="IT892_000652"
     CDS             complement(51197..52882)
                     /gene="btsS"
                     /locus_tag="IT892_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulatory system sensor histidine
                     kinase BtsS"
                     /protein_id="HAP3133895.1"
                     /translation="MYDFNLVLLLLQQMCVFLVIAWLMSKTPLFIPLMQVTVRLPHKF
                     LCYIVFSIFCIMGTWFGLHIDDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSM
                     GGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQMLIILA
                     IARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSATALKVAAS
                     TEGILRQGFNEVNSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISST
                     YTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQRVMGTIKLYEAKNR
                     LFSSINRTLGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIK
                     AVIRRDSEQASQLVQYLSTFFRKNLKRPSEFVTLADEIEHVNAYLQIEKARFQSRLQV
                     NIAIPQELSQQQLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNA
                     GLYQPVTNASGLGMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLPWRDEA"
     gene            53104..53843
                     /gene="mlrA"
                     /locus_tag="IT892_000653"
                     /pseudo
     CDS             53104..53843
                     /gene="mlrA"
                     /locus_tag="IT892_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416631.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MlrA"
     gene            53903..54010
                     /locus_tag="IT892_000654"
     CDS             53903..54010
                     /locus_tag="IT892_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohO"
                     /protein_id="HAP3133896.1"
                     /translation="MRIAKIGVIALFLFMALGGIGGVMLAGYTFILRAG"
     gene            complement(53991..54722)
                     /gene="yehW"
                     /locus_tag="IT892_000655"
     CDS             complement(53991..54722)
                     /gene="yehW"
                     /locus_tag="IT892_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehW"
                     /protein_id="HAP3133897.1"
                     /translation="MKMLRDPLFWLIALFVALIFWLPYSQPLFAALFPQLPRPVYQQE
                     SFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWGAEFRPLVETIAAVGQTFPPVAV
                     LAIAVPVIGFGLQPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRLR
                     KVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGAL
                     LVALAAIIADRLFERLVQALSQHAK"
     gene            complement(54727..55653)
                     /gene="yehX"
                     /locus_tag="IT892_000656"
     CDS             complement(54727..55653)
                     /gene="yehX"
                     /locus_tag="IT892_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter ATP binding
                     protein YehX"
                     /protein_id="HAP3133898.1"
                     /translation="MIEFSHVSKLFGAQKAVNDLNLNFQEGSFSVLIGTSGSGKSTTL
                     KMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWSVAQNIATVPQL
                     QKWSRARIDDRIDELMALLGLESNLRERYPHQLSGGQQQRVGVARALAADPQVLLMDE
                     PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDHGEVVQQGN
                     PLTMLTRPANDFVRQFFGRSELGVRLLSLRSVADYVRREERADGEALAEEMTLRDALS
                     LFVARGCEVLPVVNMQGQPCGTLHFQDLLVEA"
     gene            complement(55646..56803)
                     /gene="yehY"
                     /locus_tag="IT892_000657"
     CDS             complement(55646..56803)
                     /gene="yehY"
                     /locus_tag="IT892_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehY"
                     /protein_id="HAP3133899.1"
                     /translation="MTYFRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQL
                     WPQTIWMLVGVGCAWLTACFIPGKKGSICALILAQFVFVLLVWGAGKAATQLAQNGSA
                     LARTSLGSGFWLAAALALLACSDAIRRISTHSLWRWLLHMQIAIIPLWLLYSGTLNDL
                     SLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNV
                     IQTVPSVALFGLLIAPLAALVTAFPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVV
                     GLNQIPRDVLESARAMGMSGARRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIG
                     AGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALLKVKRND"
     gene            complement(56810..57727)
                     /gene="osmF"
                     /locus_tag="IT892_000658"
     CDS             complement(56810..57727)
                     /gene="osmF"
                     /locus_tag="IT892_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein OsmF"
                     /protein_id="HAP3133900.1"
                     /translation="MPLLKLWAGSLVMLAAVSLPLQAASPVKVGSKIDTEGALLGNII
                     LQVLESHGVPTVNKVQLGTTPVVRGAITSDELDIYPEYTGNGAFFFKDENDAAWKNAQ
                     QGYEKVKKLDSEHNKLIWLTPAPANNTWTIAVRQDVAEKNKLTSLADLSRYLQEGGTF
                     KLAASAEFIERADALPAFEKAYGFKLGQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMA
                     YGTDGPVAALGLQTLSDPKGVQPIYAPAPVVRESVLREYPQMAQWLQPVFASLDAKTL
                     QQLNASIAVEGLDAKKVAADYLKQKGWTK"
     gene            complement(57979..60276)
                     /gene="bglX"
                     /locus_tag="IT892_000659"
     CDS             complement(57979..60276)
                     /gene="bglX"
                     /locus_tag="IT892_000659"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HAP3133901.1"
                     /translation="MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKK
                     MTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRL
                     KIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVD
                     VSRDPRWGRASEGFGEDTYLTSTMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEG
                     GKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRD
                     QWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLIKS
                     GKVTMAELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVAR
                     ESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNAV
                     GENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAV
                     VGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADA
                     ILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKP
                     NKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKRE
                     GATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYD
                     AEPGKFNVFIGTDSARVKKGEFELL"
     gene            60472..62187
                     /gene="dld"
                     /locus_tag="IT892_000660"
     CDS             60472..62187
                     /gene="dld"
                     /locus_tag="IT892_000660"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HAP3133902.1"
                     /translation="MSSMTTTDNKAFLNELARLVGHSHLLTDPAKTARYRKGFRSGQG
                     DALAVVFPGSLLELWRVLKACVTADKIILMQAANTGLTEGSTPNGNGYDRDIVIISTL
                     RLDKLHVLGKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
                     GSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRH
                     DGRHAHDYDYVHRVRDIEADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQ
                     QVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIAEKYGKDTFLMIDKLGT
                     DKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHL
                     LLKMAGDGVGEAKSWLVDYFKQAEGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSD
                     EVEDILALDIALRRNDTEWYEHLPPEIDSQLVHKLYYGHFMCYVFHQDYIVKKGVDVH
                     ALKEQMLELLQQRGAQYPAEHNVGHLYKAPETLQKFYRENDPTNSMNPGIGKTSKRKN
                     WQEVE"
     gene            complement(62225..63157)
                     /gene="pbpG"
                     /locus_tag="IT892_000661"
     CDS             complement(62225..63157)
                     /gene="pbpG"
                     /locus_tag="IT892_000661"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311048.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HAP3133903.1"
                     /translation="MPKFRVSLFSLALMLAVPLAPQAVAKTAAATTASQPEIASGSAM
                     IVDLNTNKVIYSNHPDLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVY
                     SRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTR
                     FVEPTGLSVHNVSTARDLTKLLIASKQYPLIGQLSTTREDMATFSNPTYTLPFRNTNH
                     LVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTW
                     IETGKVMPVPAAALSYKKQKAAQMAAAGQTAQND"
     gene            complement(63331..63918)
                     /locus_tag="IT892_000662"
     CDS             complement(63331..63918)
                     /locus_tag="IT892_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014170891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HAP3133904.1"
                     /translation="MSHVWGLFSHPDREMQVINRENETISHHYTHHVLLMAAIPVICA
                     FIGTTQIGWNFGDGTILKLSWFTGLALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPS
                     LAHCMVFAGYVATPLFLSGLVALYPLVWLCALVGTVALFYTGYLLYLGIPSFLNINKE
                     EGLSFSSSTLAIGVLVLEVLLALTVILWGYGYRLF"
     gene            64088..64666
                     /locus_tag="IT892_000663"
     CDS             64088..64666
                     /locus_tag="IT892_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HAP3133905.1"
                     /translation="MDLNTLISQYGYAALVIGSLAEGETVTLLGGVAAHQGLLKFPLV
                     VLSVALGGMIGDQVLYLCGRRFGGKLLRRFSKHQDKIERAQKLIQRHPYLFVIGTRFM
                     YGFRVIGPTLIGASQLPPKIFLPLNILGAFAWALIFTTIGYAGGQVIAPWLHTLDQHL
                     KHWVWLILVVVLVVGVRWWLKRRGKKKPDHQA"
     gene            complement(64796..65557)
                     /locus_tag="IT892_000664"
     CDS             complement(64796..65557)
                     /locus_tag="IT892_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP3133906.1"
                     /translation="MAQVAIITASDSGIGKECALLLAQQGFDIGITWNSDEEGGKDTA
                     REVVSHGVRAEIVQLDLGKLPEGAQALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFD
                     EWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRVINITSVHEHTPLPDASAYTAAKHAL
                     GGLTKAMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIA
                     SLVAWLCSEGANYTTGQSLIVDGGFMLANPQFNPE"
     gene            complement(65610..67136)
                     /gene="mdtQ"
                     /locus_tag="IT892_000665"
     CDS             complement(65610..67136)
                     /gene="mdtQ"
                     /locus_tag="IT892_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311052.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance outer membrane protein
                     MdtQ"
                     /protein_id="HAP3133907.1"
                     /translation="MPLMYCHAKLKNISQHTVIFAHLFLPDYSPMNRDSFYPAIACFP
                     LLLMLAGCAPMHETRQALSQQTPAAQVDTALPTALKNGWPDSQWWLEYHDNQLTSLIN
                     NALQNAPDMQVAEQRIQLAEAQAKAVATQDGPQIDFSADMERQKMSAEGLMGPFALND
                     PAAGTTGPWYTNGTFGLTAGWQLDIWGKNRAEVTARLGTVKARAAEREQTRQLLAGSV
                     ARLYWEWQTQAALNTVLQQIEKEQNTIIATDRQLYQNGITSSVEGVETDINASKTRQQ
                     LNDVAGKMKIIEARLSALTNNQTKSLKLKPVALPKVASQLPDELGYSLLARRADLQAA
                     HWYVESSLSTIDAAKAAFYPDINLMAFLQQDALHLSDLFRHSAQQMGVTAGLTLPIFD
                     SGRLNANLDIAKAESNLSIASYNKAVVEAVNDVARAASQVQTLAEKNQHQAQIERDAL
                     RVVGLAQARFNAGIIAGSRVSEARIPALRERANGLLLQGQWLDASIQLTGALGGGYKR
                     "
     gene            67270..67353
                     /gene="yohP"
                     /locus_tag="IT892_000666"
     CDS             67270..67353
                     /gene="yohP"
                     /locus_tag="IT892_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohP"
                     /protein_id="HAP3133908.1"
                     /translation="MKIILWAVLIIFLIGLLVVTGVFKMIF"
     gene            complement(67726..68673)
                     /gene="dusC"
                     /locus_tag="IT892_000667"
     CDS             complement(67726..68673)
                     /gene="dusC"
                     /locus_tag="IT892_000667"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(16) synthase DusC"
                     /protein_id="HAP3133909.1"
                     /translation="MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVK
                     VFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKT
                     VNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQA
                     GATELVVHGRTKEQGYRAEHIDWQAIGDIRQRLNIPVIANGEIWDWQSAQQCMAISGC
                     DAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQW
                     LSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDIEKL"
     gene            68912..69310
                     /locus_tag="IT892_000668"
     CDS             68912..69310
                     /locus_tag="IT892_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAP3133910.1"
                     /translation="MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGML
                     ILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAV
                     STLVVFLVVSWSSQLVHGERKVVGQKGSEE"
     gene            69307..70002
                     /locus_tag="IT892_000669"
     CDS             69307..70002
                     /locus_tag="IT892_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidB/LrgB family autolysis modulator"
                     /protein_id="HAP3133911.1"
                     /translation="MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPF
                     LMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVA
                     MVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
                     FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLI
                     APFLFPIILAVMG"
     gene            70132..71016
                     /gene="cdd"
                     /locus_tag="IT892_000670"
     CDS             70132..71016
                     /gene="cdd"
                     /locus_tag="IT892_000670"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAP3133912.1"
                     /translation="MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSA
                     TGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVH
                     AEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDY
                     LPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECK
                     DGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDAT
                     SATLKALGCHSIDRVLLA"
     gene            71166..71885
                     /gene="sanA"
                     /locus_tag="IT892_000671"
     CDS             71166..71885
                     /gene="sanA"
                     /locus_tag="IT892_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane permeability protein SanA"
                     /protein_id="HAP3133913.1"
                     /translation="MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPY
                     RQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTM
                     RKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
                     GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPED
                     AQGYPAVTPEQLLELQKKQGK"
     gene            71888..72127
                     /locus_tag="IT892_000672"
     CDS             71888..72127
                     /locus_tag="IT892_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2542 family protein"
                     /protein_id="HAP3133914.1"
                     /translation="MDVQQFFVVAVFFLIPIFCFREAWKGWRAGAIDKRVKNAPEPVY
                     VWRAKNPGLFFAYMVAYIGFGILSIGMIVYLIFYR"
     gene            72321..73559
                     /locus_tag="IT892_000673"
     CDS             72321..73559
                     /locus_tag="IT892_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAP3133915.1"
                     /translation="MPQQNYLDELTPAFTSLLAIKEASRCLLCHDAPCSQACPAQTDP
                     GKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQSGCTRAGVDAPIDIGRLQ
                     RFVTDFEQQTGMEIYQPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAHPG
                     GWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEVGNTLTLEQLKAENRAVLVTVG
                     LSSGSGLPLFEHSDVEIAVDFLQRARQAQGDISIPQSALIIGGGDVAMDVASTLKVLG
                     CQAVTCVAREELDEFPASEKEFTSARELGVSIIDGFTPVAVEGNKVTFKHVRLPGELT
                     MVADKIILAVGQHARLDAFAKLEPQRNTIKTQNYQTRDPQVFAAGDIVEGDKTVVYAV
                     KTGKEAAEAIHHYLEGACSC"
     gene            73553..74788
                     /gene="preA"
                     /locus_tag="IT892_000674"
     CDS             73553..74788
                     /gene="preA"
                     /locus_tag="IT892_000674"
                     /EC_number="1.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="HAP3133916.1"
                     /translation="MLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGV
                     VFKTIGFFIANEVSPRFDHLVKEDTGFIGFKNMEQIAEHPLEENLAALRRLKEDYPDK
                     VLIASIMGENEQQWEELARLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYC
                     RAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMP
                     IVNGKSSISGYSGKAVKPIALRFIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGA
                     ATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFDSLQEMVGLANNNIVPAEDLDRSYI
                     VYPRINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGC
                     IELGEVKFKKGEKEHPVTL"
     gene            complement(74859..75869)
                     /gene="mglC"
                     /locus_tag="IT892_000675"
     CDS             complement(74859..75869)
                     /gene="mglC"
                     /locus_tag="IT892_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HAP3133917.1"
                     /translation="MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSN
                     ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMAT
                     MPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
                     ISGFDSGFSTFAQGFVVLGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPE
                     AAKVSGVNVGLNLLMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGG
                     VSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYAR
                     KK"
     gene            complement(75885..>76204)
                     /locus_tag="IT892_000676"
     CDS             complement(75885..>76204)
                     /locus_tag="IT892_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP3133918.1"
                     /translation="TQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEI
                     YQLIAELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQNEILRLAS
                     LHL"
BASE COUNT        19033 a        19782 c        18441 g        18948 t
ORIGIN      
        1 gaaattcaaa gtttctacta aaaacttttt gttccttaaa tagaaaagca actaatttac
       61 tagcgtacgc tttgggtata aagccaattc ttttgaatgc ctctgtcact tgatttatat
      121 cagatttagt atggaaatat ttctttatat atttcgccgc tgaatcaata aatgacaatt
      181 ctaacgccct gtcatgccta gaatgtctca aatagaatga tgtgcttgga ggaggactgt
      241 cttccttacc cttcaaaatt agatttggta tgaactgccc aagattttta gctattatcc
      301 catcacgctc tattgtttta tcatctgatt caatgagtaa tttaacatta ctactctcat
      361 ccattgaaat aaatattgtt aaatcagcca atataagctt aatcgttttc gtttttgttt
      421 ttttatcttt agagtaaaca gttaactctg cttcaatatc tgttggttgc tttgctaaat
      481 cagtagaacg ataatatgta tatctttgtg aaacctctgg cggaattgag agtgaaaaac
      541 taaacgtaat ttcttttttt tcagactttc gggaaagtac atctgtaaaa tcgccaaaat
      601 ccacatatct cccataccat agtattgggc cagtagtatt ttcttctaca gattgacgaa
      661 gtaaaggaaa tgtgcgcaat agggaacttt taccactgct gttcttacca acaaatactg
      721 taattggttt taaatcaata aacgttttgt tgacaaagct cctgaagttt tgaagaccta
      781 tacccttaat cattcctagc tccattagtt caataaaatc aatcgatttt gagacaatct
      841 taatatcttt gacaggcgcg cgcaatgctt accccgcctc gcctgcccgc tttatgggtc
      901 gtttttaatg cagttgcatg accactctgg atccgcgcct gctctggcgg cgcgcggcca
      961 gaacaggcat ccccaacgca tgcaaaaaaa tgcacctgtt gcatgcacgg ctaaaaaacc
     1021 gggaaattgt gggaaaattg cataataaaa ccgactttaa tcgtgccggt tgggggtggt
     1081 ctctacggtg caggctaacg tctcgcgggg ctcgttgctc aacaccgctg gcactgaaaa
     1141 caagtttcag caccggcggc gtttgctatg gtcgacgcgg tggtggcttt gccatatttg
     1201 gtggccgaaa cgcctcaatt ttcggattgc tgatatcgct gtatttgcgg tgattatccc
     1261 ggacgacacc ggcacacccg accagttcgt caggggtcag attctcgtta atcataattt
     1321 gttgcaggcg atgtacgacg gccatcagct taatgttttg cgttgaatgt atcggcggca
     1381 ctggcatcat tcgcatatga ctcattttaa ccacccattt ttttagcatc tgcgaccaac
     1441 ttgtcggaat attgccagac accatcatca gcgatgtaag ccctaccaga aacgctgtta
     1501 agtgtttcat atctaatagc cagccctaac gggtgtagaa tttcgtgatt aactctgaaa
     1561 acaagcccct tctcgcttaa ctctttccag ttcattaggg acataccgca ctggacatct
     1621 ggcatcatta actgaaaact cagcatcaca taattttccg cccattcaga taaatccgta
     1681 acgtttgtca ccctcactga tacacgtttc ccggtatatc tgtttaccgg ttcccattca
     1741 tgcaacccga gaatatcacc gctagaataa tcgcggtcat tgagacgaaa ttcagcacgt
     1801 ttttcctgag atatcacaga gttaaaatac tcaggtgcaa tttttaactc atggattttg
     1861 ctcattaatt ctgctcctct tgaattgaga atcccggcca ctcatcagca gccgcgtatt
     1921 tgattttttt atcgccataa atcaccgttg ccccacgcgc cagcgcttcg agcgcccacc
     1981 gttccggggt aatgccctcc tgagccaaat cgaaacgaat tttcgccacg cgatcccttt
     2041 ctggttttgt catcctggct gatggagctt gctcgctcgt tttgagtggc gcattgcttc
     2101 tttgctggcg attattgcga ggtgcgccag cttttaacgc gccgttaaga accttcatga
     2161 cgtctggctc attccagccg ataaccccgg cctcaatcaa atttaacacc gctgcggctt
     2221 gctcagacgg tgtaggtgtc ataactggat cgccaccgtc ggcaagcttt ccacagttat
     2281 tgacaggact ccgaggcgcg gcaaagccgc tttttaaggt caaaggctca acggccaaaa
     2341 cctttggaac tatgcgccat tccgctgtac gggttacatg tacgcggctc accccaagat
     2401 gaggggcata aataccgacc actttctcga tatcctcctc gtattcgttt acctcatccg
     2461 tcaccttacg ggcgaccctg accgcctgag catcacgctg catgtttgcc ccaccctgcg
     2521 cgctgatgta caggtcaaat tccccctcat ctgcagcagc ccggacggcc tcgacacggt
     2581 cgtcaaactc gctggcgata ctcaccccgc gcggcagctt acgcagttcg cggtaagcgc
     2641 ccattgtcgg gaggccaatc ggtttaaact gagggatacg ccatgtagac gcccatgcgg
     2701 ttacggctgc ggccgtatct ttcagagatt tgccggtatc gtgatcgagc tgaccgtcaa
     2761 gcgcgtagcc gtcgatattt ttggcaatgt atttggcgat ataacccgcc gcgcccccct
     2821 gattaaggtg acgcgactca aagcgctgtt ttgccgcgcc cttttcgtgt ccgtcctctt
     2881 tgagggcata acgacgcata atttcgttga tagctttacg ctgactgagt ttgcaaaaaa
     2941 gcatcatatg ccagtgtggc gtgccgtcgt ggtgcggctc gacaacgcgc atcccataca
     3001 cttccaaatc gttatctttg aaagcggtac gcatcaggct ccagattcgg cacagatagc
     3061 gctggccgtt tttaggggtg aatgcggttt cgttccagcc gtgattgagc tgcaccgttt
     3121 tgctgtcacc tttgccgacc tgtcgggtcg ggtgatactt cgacggcgtg gtcagcgtga
     3181 taaacattcc cacatcacca acgctggccg catagcgttc aattccggca atggtgttca
     3241 tcagctccat acggcgtatt tcagggtttg aaatactccc catgacttta ctgatgaggt
     3301 cgatacgttc gccggtaact ttgttttcca gctcacagga tttcaggtat tcgagattag
     3361 ccagccggcg cgagtgaacc tcgcggatcg ccattttgct ggcgtaaggt gaacggtctt
     3421 tgttgacttc accggcagcg ataagcagcg cctcgcgcca gcgcatacgc tgcgccttga
     3481 gctggttaac ccaccaatca tcttttatca gacgggaaat agcggaaaac gccatgcgga
     3541 tcgttatctg acccttacgg tattttttcc agtagagcgg ggttaagttg aacgcgcgtg
     3601 caacaccagc cacctgacca tatatgtgca cctgcgcctc atcggtgaaa agggtctctt
     3661 taccgccgaa tgcctcagcc cattcgtcgc tgagttcctc gtatttacgc cagagctgcg
     3721 cggcaattct ggccgcaaat tttttcagct ctttgtcatt catatcaggc aagcgcgcat
     3781 attcgtcacg ctcagacaag aaaccaatcg acgcagattc attcatcccg cacagctcgt
     3841 taacgcgctc aagacgcggc aacagcttcc gctcaaaggt gtttttcagg aaatagagcg
     3901 ccccgagcgg gctctttgtg cgacgaatga agttataacg ggaagtaaac aacgtcttaa
     3961 gaaagaaagg caggcggtca atccggtata aaacaccttg cacctgacgg aattcggcac
     4021 gtgtaagggg tctgtcacgg ccaatggcag cgcggggagc attccaggga taagcaccaa
     4081 cgaaagtatc gccggtgcgc ttagatattg gcagggctag cgagggggca atacgccccc
     4141 gagtctcaac ggccatcagc acaaaacgcg gtctgacatt gcagtcccaa ctgctcgacc
     4201 tgctcaccca acgccgcaaa actatcagca ccgccattta aaaggtcatg tagcaccaga
     4261 ccagaaatca gtttttgaat cgtcgggtaa tacccgacag tatcaagcca ttcgctacct
     4321 ttattttttc cagcagtcgc cactttcttt tcctgcaaaa tgaactggta gcgatcgctt
     4381 gtaactacat actgatgatt tatctcgata cggatactca tttttgtctc cttctaaaat
     4441 tgattagcaa gcacaatgaa aaattgagtt gtgcaatttt tcggactctt gccccaatag
     4501 ctcgatgatc tcggtgcggt tgagttctaa cttactgatg tgcgcaatta ggcgatcaaa
     4561 atgagaggat aaacgggtcg cggtatcgag ctgcgcatcg cgcaacgctt gcgccagatg
     4621 taccgagagc acacacgtcg gcactttatt ttgtttatgc atttgcctat ctccagacaa
     4681 aaggaatccc cacgcagtaa ggcgtgtaat aaaacgaatc cagattaatt aatgtaaata
     4741 ctgctcaggc tttaccgagg ttaatatcgt tggcgcgtgt tcaaataacc caaaaagctc
     4801 acgcaaagcg cggaatagtt tctctcgcca ataacaagca tcttcgtcaa tgcgccagta
     4861 aggctgattg aactcgacct cactcaatcc cgcgtgtaga aataaagagc ggcgctgacc
     4921 caccgttaga aaactaatat atgcagattc acttgcgcca acctgacgac gttttgaaaa
     4981 agcagcgcgc agctcatcga tagcacaagc cagacgttcg cggtcgacat cattcatttc
     5041 ttcaaagtgc attactgcgt gacgctgttt taaccgagca tgaaaacaga cagtcaagcg
     5101 gtcacgctcc atcatctgat tataaaaatc acaggtatcg tgccagcgag gttccgcaag
     5161 atgctttcct ataacgacgc gtagagctgc aggttgtttt tgaactaatg caagagtcat
     5221 aaccgtcata acgatatccc tcgggatttc ataaagcgtt tagccatagc aataaatcca
     5281 ggcttgcgag tgcggatgat gatgccttta cgccctttac catgagtgat gttgaacttc
     5341 atcgggcgtg gactttcgtt acgcagtaac tgagctatac aacgtggctc tttcatttct
     5401 ggctccttat gctggttcac ctaatcccaa ccacatcaac caaccatcac gaatttcttt
     5461 agggcgactg tcataggcca tcttcatgcc tttgttccat gctggcagat atacccagta
     5521 ttcccctgct ctcccacttg tagactgcgg atcagtcatc tcaactatcg gtagtttgcc
     5581 tttctcaatc atccctttga cagcagcagg ggttttacca ataagacgcg caaactcctg
     5641 atacggaacc gcgtcgctcg cgctctcaat gaccctattc atttgtgact attcctcgtt
     5701 agtgttttaa ttgctcctaa tggcttttaa ttgccatatt ggagccataa atctgcggta
     5761 acgaagcgaa tattactccg ttatcgtttt tctatcaata gtggagtgtt aattacgatg
     5821 atacccgtca acgagaagct ggccatcatg cgtgagtcgg aacgtatgaa tagaaaagaa
     5881 ttcagtgact taactggagt tccgtatagc tctctttcta gttatgagaa gggagtaaaa
     5941 gatatgggca tacaagcagt gatgaagatt ttgaatcatc cacagttcaa aaaatatacc
     6001 atgtggttca tgactgagac gatatcacca gaagctgggc agattgcacc ggctctcgcg
     6061 cactttgggc agcagacaac aacgtcaccc cactcagacc agaaaactgg ctaaccattt
     6121 acggtgctta tctgtgcagt aaatgcacgg tgagtttttg ttatttaaat caggaaattg
     6181 aagtacgcag taacatcatc gggaggcttt atgtctgtta aaaagctcga tgatggtcgt
     6241 tatgaagtgg acattagacc tgcagggcgc aacggaaagc gcatccgcag gaaatttgac
     6301 aagaaaagcg aagctatcgc tttcgagaag catacccagt acaaccatca caacaaagaa
     6361 tggttggcga aaccgacaga taagcggcat ctgtcagagc taacaaaaat ctggtgggag
     6421 ctgaaaggca agtatgaaac tcacggccga gattacctgg gcaagttaga gttgttcaca
     6481 aagataacca gtgacccttg tgcctttcag attactaagt cattgataag ccaatacagc
     6541 actgtgcggc gttctcaagg catcaagcca tcgagtataa atcgtgattt aacgtgtctt
     6601 agcgggatgt ttaccgcgtt gatagatgcg gagctatttt tcggggagca tcctttccga
     6661 ggtcttaaaa gactcaaaga ggataagcca gaaaccggct acctgacgca agaggagatc
     6721 gcgcttctgc tgtcaaaagt ggacggtgat aataaaaaaa ttgcgattct ttgccttagc
     6781 accggcgcga gatggagtga ggcagcaaaa ctgaaagcgg aaaatatcat tcaaaatcgc
     6841 gtcactttcg ttaagacaaa aaccaacaag ccgcgaaccg ttcctatatc cgaggaactg
     6901 gcaacaatga tcacaacggg taagcgtggc tatctgttca ctgatgctaa ctatcccgcg
     6961 ttcagacggc taatgaagga gctgaaaccc gacctaccac cgggtcaggc tacgcacgca
     7021 ttgcggcaca gcttcgccac gcactttatg ataaacggag gcaacattat cacgcttcag
     7081 agaatacttg ggcattcaag aattgagcag acaatgacat atgcgcactt cgcccctgag
     7141 tacctacagg acgcgataac gcttaatcct ctacgtggtg gtgttggctc tcagagtgtc
     7201 cacacagtgt ccacagtagg gtagtttatt atggctttca gtggtcttgc gtgccgcgca
     7261 aacccgcatt gcaccgctga aagcccctgt tgtaagggta tataaacgcc cttacacggg
     7321 cttatttttt tatgcataag ccctatctct ggtaaccgtc ttccattgac cacatcgata
     7381 gaatcctcct tcatagcacg atgcctttca cttatcggca tcgtgctccc acaggttccg
     7441 gctacgcaca gccagaacgc gcatatttga cgcttaccaa aaaatattct cactctccac
     7501 atttgaatgt cagacgagcg acaccatgta atcctacacc ttctgtcttc agctcaacta
     7561 tttgcatttt tttgccctga gtaacacaga aatgagttgc atcatttttt actatatttt
     7621 ctgcaccaga tattctaccc ctggctaaag aagcttcggc ttcggtgtag tattggttat
     7681 cgagtttacg ctgaatatta cttttatatg caagaccaaa tttaccgata cttgtctcat
     7741 cattatgcac agcacaacca gacataataa aaatactaat taatgatata gcagctatct
     7801 ttttcatctc accttccccc attaaatacc aacgacactc tctagtgttt aaatataata
     7861 atggcatgat tattataatt gaataggatt ataataaatg ttctgtacaa catttcctac
     7921 ataagtagga attacggaca ttgaggccct tcagggtaac tccatggggg ctttaatata
     7981 ttatattgaa gatgccactg tttagttgaa tattaggtat atgctctttt ttgaaattta
     8041 tcggtggcag ccgttagtat tcgctgtccc cattgcaagc tcctggtggt aaccactgaa
     8101 tcctccatac ttgaactgac tttttatcct ccgactttca tcctgttctg actccacctt
     8161 ttgttttctg ctctacacta tctacagacc aatcataaag gcacatacga tcatggcaga
     8221 atttcccgcc agcttactga ttcttaatgg caaaagtact gacaatctac ccttgcgcga
     8281 agcaattatg ctgttgcgtg aggaaggaat gacgatccat gtgcgggtca cctgggagaa
     8341 aggcgatgcc gcacgatatg tagaggaggc ccggaagttg ggcgtcgcaa cggtgattgc
     8401 cggtggtggc gatggcacca ttaatgaagt ttctacggcg ttgattcagt gtgaggggga
     8461 tgacataccc gcgctgggaa ttttgccatt aggaaccgcc aatgattttg ccaccagtgt
     8521 agggattcct gaggcactgg ataaggcgct gaaactggca attgccggtg acgccattgc
     8581 gatagatatg gcgcaggtca acaaacaaac ctgttttatt aatatggcga caggcggatt
     8641 tgggacgcgt attaccacag aaacgccgga aaaattaaaa gccgcgctgg gtagcgtctc
     8701 ttacatcatt catggcttaa tgcgtatgga tactctgcaa ccggaccgtt gtgaaatccg
     8761 cggtgaaaac tttcactggc aaggtgacgc cctggtcatt ggtattggta acgggcgtca
     8821 ggccggtggc ggtcagcaat tgtgtccgaa cgcgttaatt aacgatggct tgctgcaact
     8881 gcgcattttt accggcgatg aaatacttcc ggctctcgta tcaaccttaa aatctgacga
     8941 agataacccg aatattatcg aaggcgcttc gtcgtggttt gatattcagg caccacacga
     9001 catcaccttt aatcttgatg gcgaaccgtt gagtgggcaa aattttcata ttgaaatact
     9061 tccggcagcg ttgcgttgtc gattaccacc agattgtcca ctgttgcgtt aatcaaacta
     9121 ttctctcttg aaccagggag aatccgtaat gccggatgcg gtgtaaacac cttatccggc
     9181 atacagaaca atactacacc gtaattaatt ttacccgcgt cttctgcaat gccagtttat
     9241 ccacctctga cacagcatca tcggtaataa taatgtcaat tttttcgatt ggtagtacct
     9301 gattaaaacc gcgacggtta aatttcgatg aatcgagaac ggcaatcact ttattagcgg
     9361 ctgtgaccat cgcaccgcta atagaataac cttcattaaa ggtcgtaata ccattaaccg
     9421 catcaatacc atcagcaccg acaaacatta aatcggcatt aatatcctgt aatgaacgct
     9481 cggcaatgga accatgcatc gagcgcgttt tatggcggac cgtgccacca cagacgacca
     9541 gagtaatgtc tttattttcg gaaagggcaa acgctgccgg gagactgttg gtaatcaccg
     9601 tgatattttt ggcggtcatt aatccttcgg cgataagcat tgtcgtactt ccgctgtcga
     9661 gaataacggt catcccttcg tggatcattt tgactgccgc ctgcgctatt ctgttttttg
     9721 gcgcgctggc gagctgaaat cgctctttaa acccgacttc ctgggtctcg gtttcactat
     9781 taccagacat tattttcgcc gcaccgccat gaaagcgcgt aaccacgcct ttttgttcga
     9841 gaaagcgcaa atcggcacgg attgtcgctt ccgaggcagc aaatactccc gccagatcct
     9901 gaacaagcac ggttccctgt tcattcacta attggatgat cttattcctt cgctcgaatg
     9961 aattcatcgt catttaccca tattcaattg tggctagtgt aaacgaaggg ggaccattgg
    10021 tgaatgatct gttttgcaca ataccgggcc agcatcacgc tggcccgcgg tttcagggaa
    10081 tgagcaacac tttgcccggc atagcattac gagcgatgtc acgcaccgcc tgggcgaagc
    10141 tttcaaagct tccacggtga gcgattaatg gctccaggct taacttacgt tctgtcagca
    10201 accggctcgc cgtttcccac tcctgccccg gccaagggct ggagtagttc atccaactgc
    10261 cgataaccgt cagctcttta cgcaatattt tgccaaacgt tgccgatgtt aaatgcagat
    10321 cctgatgcaa cgtgcccacc agcgccagtt gggcatgagg accggcaatc tctaccgcca
    10381 gttcgacagt ttgcggtacg ccagccgtct cgaggataag ctgattaaag cgcagttcgc
    10441 gtaaaacgct ctgcatttgc ggcgcgctca tttcgctact gttaaatgtt tgcatcgcac
    10501 cgaaagattt tgccagtgcc agtttttctg aactaatgtc gatcgccgtc acactctttg
    10561 ctcccagcgc gacagcgcac tgaatggcca gcaggccaat ggttccggca ccaataataa
    10621 taacgttttt attctcacaa ccttgcgcta aatgaaaagc atgcagacca acggtaatcg
    10681 gctcaataaa agccccatcc tcaataggca tatccgtggg tagagcaaag acattttttc
    10741 gcttaacgac aatatattca gcaaatccac catcacgccg cgagccaata aaatcatatt
    10801 ttgcgcactg ggaataaaac cctttcagac actctggaca agtaaaacag ggtaataacg
    10861 gcacacaggc aaccgcatcg ccagggtgta aatcatcaac accggatccc accgcatcaa
    10921 tatagccgct aaattcatgg cctaacgtta ttggataata atgtgcacca tttttaaata
    10981 tcctgggtaa atcggaacca cataagcccg agctggcaat ttttacccgc acctcatcct
    11041 gatgtttaat ttcaggaatg acgctttctg caacgcgcac gataccatca gtatcattca
    11101 ccactgattt cataaaaact cctgattgtt aagggggata acctccccct caggtaaaaa
    11161 ttattctgcg agaacgactt tctcttgttt aataaagcca cgcgctctac gccaggtcat
    11221 gaaaataccg gtcagataaa ttgcaccgat aataatgaaa ccgggaatat tttgcgggga
    11281 gaaaacctga atcagtaacc aggtaatggg agaaccgccc tgatccattg aagccaccat
    11341 acccccggct tttaacgccc cagcattagc cgccagttgg gtgtgcaaac caatagtttg
    11401 cgtcgcgatc cacagggtga tgctcataat gatgacaccc gagattaagg tgcggaacag
    11461 atttccacga tgcacggcga ccgccatcgc cacgaagaag ccgatggtgg caagatcgcc
    11521 aaacggcagc acctgattac ccggcacaca aacagcaatt aaaatggtga gtgggataaa
    11581 aatcaggctt gccgatacca ccgccgtatg tcccagcagc aacgccggat caaggccaat
    11641 caggaactcc tgaccgccga acttcgcctg taaacgacta cgagcctgct tagcgatggg
    11701 cgttaaacca tccatgatgg gtttaatcac ccgtggcatt agcagcatca ctgccgccgt
    11761 ttttaccgcc agctgcaata cacctttgac atcgtaaccc gcgaggatgc cgataatcag
    11821 ccccatcaca aaacccacgg tgacaggctc gccaaatgga ccaaatttgc gctgaatatc
    11881 gtcggcgcta aatttaattc ggttaacgcc tgggattttc tcgatgatag catcgaccag
    11941 caccgcaatc ggccccatat acgccgacgt accgtgcgga atagcaatac cttccagctc
    12001 aaagaaattt cgggtatcgc gggcaaacca gtcgccgagc ttataaacaa acgccgcgtg
    12061 aattaccaca cctgccatcc ctatcatcca tgaaccggtt gccagatgca gcaacgcgcc
    12121 ggtgaaggtc atatgccaga tattccagat atcaacattt accacccgcg tcatacgggt
    12181 cagtaacatg gccacgttaa ccagaatcgc aatcggaatc gccaccagcg caatttgcga
    12241 cgcccaggtc attggtgaag agcccggcca gccaacatcg accacatgca gattcaggtc
    12301 gaaattttcc gccatcgctt tcgccgccgg gccaatggaa tccagcatta agccaatcac
    12361 aaggccaatg ccaacaaagc caatcccgat atgcagaccc gctttaaagc aatcgcctgc
    12421 cttcatgcct aatattttag aaaaaataat gatgacaatc ggcagcatca ccgtagggcc
    12481 gaggtcgaga atataacgca tgacttctga aaacataggt cacccctgta agatagtcag
    12541 aattttattt tgtaatgctt cgataccgat accagaaata aaaggcatgc cgtgaactaa
    12601 cggaatatcg ccaaaactac gatccacttt ggcagtggtg catatcaaat gcacaccatc
    12661 catataggtt tctatttcat taacccgaca ctggattaat tcaacaggaa tattatgatt
    12721 ctgacacaac tctttaattt cttccgccgc catcgtagag gtcgcaaccg cgcctccgca
    12781 agcgacaata atcttgcgtt tcataaatag tcctttttat tgttacagag ggatttattc
    12841 gtctgaatct aaaacatact ttgtgaagta ttcctttaac tgggtttcag gaagagtgat
    12901 tagtgtctcg acgatatcgg gctgttgtaa cttgccaaat aaacagcgta aaagtttcaa
    12961 ttgctgctgc ggattttcca caatcaacgc aataaccaac gataccgcca cgtcgttatc
    13021 atcatccgct tgctgaaaat gaactttatt tgttggcctt aacagataaa tggctgacga
    13081 cttagcatga atcgcctcac aatgcggtat tgcaatagcg tgctgctcaa gcattatccc
    13141 ggtagggaat tctgcttctc tggcaattaa tgcctgtggc caggtatcat gaaccacacc
    13201 tttggcgagc atctcattac cgatatgggt taaaacttcg ctacgatcga caaaagaaat
    13261 tccgctacga acaaacaggt tagtcatata ccgtccttat tccgcacagc cgtagcgata
    13321 ggcgcgcaaa acatcataaa ttttatccat aatcagctga tgcggtattg ctgataattc
    13381 cccggactga atgcgttcaa attgtttggg aagatactga ctaatcatgc ccagtgggat
    13441 gtccacgcct tcaagattca ccatcatcgt atcgacgcta tttttaatcc gactatgcgg
    13501 ccagtaataa cgaatacgat ccgacaggct gtaacgaata tccagtaatg aatcgttaaa
    13561 acccgtacga taatattttt tccagtattg cggttcgtcg agcatcactt cttcaattac
    13621 cgccaggcaa ccgctgcgat tttcaggggc gataagttcc tgctcaattt gtgccagtgc
    13681 aaatatcgcc tcgcgtaaag caaaggttaa tgcgggaccg actttcaata ttgcaaagtg
    13741 atcgcggact aattcccaat aagccgtccg ggtctggtaa tcggtagaat gtgcttcata
    13801 aaccattcgg gtgttttcta tccattgcgc cagcggctgc gcttcctgcg gctgataatg
    13861 gataatattg ctgtgttcaa attccacacc cggctgcacc acgatggcaa tcacacgtgt
    13921 taacgcctct gtcagcccac gggcaataaa ggccttttga tgcgtacgta aagtattggc
    13981 ggcatcttca acatgggtga tgtgtactga ctgaatggcg ctggcctcac cgcccggaac
    14041 cggaacttcg gtgccaatga catagctcag ttgctcacgc tggcaatctg tcgccacact
    14101 ttccgcagca aagcaaagca cagcagctcg ttccacaacc gtttctggtg ctaacggtat
    14161 gggatccccc gcgcaggaca ttgacgcatc aagatgaatt ttactgaagc cggcacgaac
    14221 atattccttt accagctcga cggatttttc catcgccgca tccgcatttt cttgctgcca
    14281 gcagtttggc cccagatgat cgccgccgag aataatgcgt tcgcgtgcaa acccaacttt
    14341 atcggcaatc gtaaaaacaa attcgcgaaa gtctgccggt gtcattccgg tataaccgcc
    14401 aaattgattg acctggtttg acgttgcttc aatcagcact ttgcgcgtgc tgttgcgatc
    14461 aaatgccagc gccgcttcga taaccaacgg atgggcagaa cagactgaac atatgccgat
    14521 atgttcacca gctttatgcc gggcaattaa cgttttcatg ttttttcctt gttaaatggc
    14581 aggtgcgtta tgccctgccc tcgcagccac aatcggcaat cactttgctc accacatcgc
    14641 gcattgcgga tttagccgac tgcaaataat cccggggatc ggtcgcttca gggtgctcgg
    14701 tcaggtaatt ttttaacgcc tgcgagaagg catttttcag ctccgttgca acgttgattt
    14761 tgcatatccc cagtttgatg gtttgctgaa tatccttagt cgataaccct gacgcgccat
    14821 gcagcaccag cggtaagttc acccactggc gaatgttctc cagtctagaa aaatcaagcg
    14881 ccggtgcgct ggcatacatc ccatgagccg tgccgatggc gaccgccagg gaatcaattc
    14941 cggttgcctc ggcaaattca cgcgcctgag cggggttggt gtacaacgca tcggcttcat
    15001 tgacttgcac atcatcttcc tggccgccaa gttgccccag ctccgcctcg acgctgacat
    15061 caaagcgatg gcaaaaatcc accacctctt tgacccgtga aatattttgc gcaaaaggca
    15121 aatgcgaggc gtcaatcatg actgagcgca cgccagaacg aaccttctga gcgatatcgt
    15181 caaatttcgt gtgatggtcg agatgaattg ccagtggatg gtgatattgc ttcgccatcg
    15241 cgctgaccag cgccaacaga ttttctgtac cagcatgagt aaatgtgcca ggcgttccgg
    15301 cgatgatgac cggcgcatgc aggttggcag cggtttctac caccacttgc atcgtttcga
    15361 gattgtgaat attgaatgcc ggaaccgcat aaccgccgcg ctgtgcgttg ttcagcatct
    15421 gctttgtcga taccacgtac attttcatat cctgtcgttt gttttcgatt tcaaaatata
    15481 atgaaattat ttatttttaa atatcgagat aacgatcaca aaaacgacaa tatgaaaatt
    15541 gttcgaggag tgaaaggcaa aaaaacggcc tcccgatagg gaagccgtag caaagtgcgc
    15601 gtgtttttat gccggatgcg gtgtaaacat acgtggcagt gctatgtagg catgataaga
    15661 cgcttcagcg tcgcatcagg cataggttgc cggatgcagc gtaaacgcct tatccgtcct
    15721 acggggtggt gttgttcgta taaggcgtat caggcgatag taattttgct atcgagataa
    15781 acgtcctgca cggcgttaat cagtttcacg ccgtcagcca tcgatttctt gaacgcttta
    15841 cgtccaagaa tcagccccat tccgccagcg cgtttgttga taaccgcagt acgcactgca
    15901 tcactgaggt cagtttcacc gcccgcagca ccgccggagt ttatcaaccc agcccggccc
    15961 atatagcagt tagctaactg ataacgcacc agatcaatcg ggttttcgct ggttaacttg
    16021 ctgtacacgc gatcgtcggt ataaccgtaa ttaatcgctt tataaccgcc gttattttcc
    16081 gccattttct gtttgacgat gtccgcgcca atggtcgccg ccagatggtt cgcctgacca
    16141 gtcaggtcgg cggaaacatg gtaatcaacg ccatctttct taaaggcgga gttacgcaaa
    16201 taggcccaca gcactgtcac catgcccagc tcgtgcgcac gttcaaaagc cgcagaaatt
    16261 tcttcaatct ggcgacgtga ctcttccgag ccaaaataga tagtcgcacc aaccgcaacc
    16321 gcgcccatgt tgaacgcctg ctccacgctg gcatacagcg tttgatcgta ggtattcggg
    16381 taacttagcg tctcgttgtg attaagtttg acaaggaatg gaatgcgatg cgcataacgc
    16441 cgcgataccg acgccagcac gccgtaagtt gacgccacac agttacagcc cgcttcgatc
    16501 gccagttcaa caatgttttt cgggtcaaag tagagcgggt tagcagcaaa tgaagctccg
    16561 gcagagtgct caacgccctg gtcaaccggc agaatagaaa gatatcctgt gccagccaga
    16621 cgcccggtgt tgtacaacgt ctgcatatta cgtaacaccg caggcgggcg attattgtca
    16681 atcatcacgc ggtctacgta gtcatgtccg gggagataaa gctggtcaga aggaatagtc
    16741 atacaacggt gctgtaaaag gttgtcggcg tctttgccaa gcaactgcgc aatatctgtc
    16801 attactatgc tcccgtaaat tccgattgga tatcggctat ggattttcct ggcccgcctt
    16861 ttgcgggcaa tcataatcct ggtcgttacg ggcgagtttt tccatctttt ggatgttttt
    16921 tcagcgtttt ctgttggctc gattcatcag aaaaaatgtt agtgcggtca agttttcacc
    16981 gcaaaggtat ttaaaaggta ttattaagtg gtattgtcat cgcgtacctt acattacctg
    17041 tcatgaagga attaaaagat gaaaacaaca gcaaagctgt cgttcatgat gtttgttgaa
    17101 tggtttatct ggggcgcgtg gtttgtgcca ttgtggttgt ggttaagtaa aagcggtttt
    17161 agtgccggag aaattggctg gtcgtatgcc tgtaccgcca ttgcggcgat cctgtcgcca
    17221 attctggttg gctccatcac tgaccgcttt ttctcggcgc agaaagtgct ggcggtattg
    17281 atgttcgcag gcgcgctgct gatgtatttc gctgcgcaac agaccacttt tgccgggttc
    17341 ttcccgttac tgctggccta ctcgctaacc tatatgccga ccattgcgct gactaacagc
    17401 atcgcttttg ccaacgtgcc ggatgttgag cgtgatttcc cgcgcattcg tgtgatgggc
    17461 actatcggct ggattgcctc cggtctggca tgtggtttct tgccgcaaat actggggtat
    17521 gccgatatct caccgactaa catcccgctg ctgattaccg ccggaagttc tgctctgctc
    17581 ggtgtgtttg cgtttttcct gcccgacacg ccaccaaaaa gcaccggcaa aatggatatt
    17641 aaagtcatgc tcggcctgga tgcgctgatc ctgctgcgcg ataaaaactt cctcgtcttt
    17701 ttcttctgtt cattcctgtt tgcgatgcca ctagcgttct attacatctt tgccaacggt
    17761 tatctgaccg aagttggcat gaaaaacgcc accggctgga tgacgctcgg ccagttctct
    17821 gaaatcttct ttatgctggc attgccgttt ttcactaaac gctttggtat caaaaaggta
    17881 ttattgcttg gtctggtcac cgctgcgatc cgctatggct tctttattta cggtagtgcg
    17941 gatgaatatt tcacctacgc gttactgttc ctcggtattt tgcttcacgg cgtaagttac
    18001 gatttttact acgttaccgc ttacatctat gtcgataaaa aagcccccgt gcatatgcgt
    18061 accgctgcgc aggggctgat cacgctctgc tgccagggct tcggcagttt gctcggctat
    18121 cgtcttggcg gtgtgatgat ggaaaagatg ttcgcttatc aggaaccggt aaacggactg
    18181 actttcaact ggtccgggat gtggactttc ggcgcggtga tgattgccat tatcgccgtg
    18241 ctgttcatga tttttttccg cgaatccgac aacgaaatta cggctatcaa ggtcgatgat
    18301 cgcgatattg cgttgacaca aggggaagtt aaatgaaaac agaacgtatt ctcggtgctc
    18361 tttatgggca ggcgttaggg gatgcgatgg ggatgccctc cgagctttgg ccacgcagcc
    18421 gcgttaaagc acactttggc tggattgacc gttttcttcc tggaccaaag gagaataacg
    18481 cggcctgtta ttttaaccgc gccgaattca ccgacgatac ctcgatggcg ctgtgtctgg
    18541 cggatgcgtt actggaacgt gaaggcaaga tcgatccgaa tctgattggg cgtaatattc
    18601 tcgactgggc gctgcgtttc gacgccttta acaaaaacgt acttggtccg acctcgaaga
    18661 ttgcgcttaa cgccattcgc gacggtaaac ccattgctga actggaaaac aacggcgtga
    18721 ccaacggcgc agcgatgcgc gtctcgccat taggttgttt gcttccggcg cacgatgttg
    18781 attcctttat tgatgatgtg gcgctggcgt ccagcccgac ccataaatcc gatctggcgg
    18841 ttgcaggcgc ggtagtcatc gcatgggcga tttctcgtgc cattgacgga gaaagctggt
    18901 cagcgattgt agattcactg ccttcaattg cgcgacatgc acagcaaaaa cgcatcacta
    18961 ccttcagcgc ctcactggca gcacgtctgg agattgcgct gaaaattgtg cgcaatgccg
    19021 acggcaccga atccgccagc gaacagcttt accaggtcgt tggcgcaggt accagcacta
    19081 ttgagtccgt tccgtgcgcc attgcgctgg ttgaactggc acaaaccgac ccgaatcgct
    19141 gcgccgtcct gtgcgctaac cttggcggcg acacagacac catcggcgct atggcgacgg
    19201 cgatttgcgg cgcgttgcat ggcgttaacg ctatcgatcc tgcattaaag gcggaactgg
    19261 atgcggtaaa tcagcttgat ttcaaccgct atgccacagc gctggcgaaa tatcgtcaac
    19321 aacgggaggc ggtatgagcg gcgctcgatt acacacgctg ctgcctgaat taacctcgcg
    19381 tcagccggtg atggtcgtcg gcgcggcggt cattgatgtg atcgccgacg cttatgccct
    19441 cccctggcgc gggtgcgata tcgaactgaa gcagcagagc gttaacgttg gcggctgcgc
    19501 actgaatatt gccgtggcgt taaagcgcct cggcatcgaa gcgggtaatg ccttgccgct
    19561 cggtcagggc gtgtgggcgg agattattcg caaccggatg gcgaaagagg ggttaatcag
    19621 cctgatcgat aacgccgaag gcgataacgg ctggtgtctg gcgctggttg agccggatgg
    19681 cgaacgcact tttatgtcat tcagcggtgt ggaaaatcag tggaatcgcc agtggctggc
    19741 gcgattaacc gttgcgcctg gcagcctgct ctatttttcc ggttatcaac tggcctcgcc
    19801 ctgcggcgaa ttgttagtgg aatggctgga aaagctgcaa gacgtgacgc cgtttatcga
    19861 ttttggccca cgtatcggcg atatcccgga cgcattactg gcgcggatca tggcctgtcg
    19921 acctttagta tcactcaatc gtcaagaggc tgagattgcc gccgaacgtt ttgctttatc
    19981 cgcagagata acaacacttg gcaagcaatg gcaggagaaa tttgccgcgc cgttgatcgt
    20041 tcgtctcgat aaagagggtg catggtattt cagcaacgac gcttctggct gcattccggc
    20101 atttccaacg caagttgtag acaccattgg ggcgggcgac agtcatgcag gtggcgtact
    20161 tgccgggctg gcctctggtc tgccactggc ggatgccgta ttactgggca atgcagtggc
    20221 gtcgtgggtt gtcgggcatc ggggcggtga ttgtgcgcca acgcgcgagg aactactcct
    20281 cgcacacaaa aacgtataga tcgctgcgac agtggctaat gctgtactca ataggccgtt
    20341 gctgttggtc aagcgccact tgcttgatca ccagcaccgg tattttgcta tctaactgaa
    20401 tatgtgactg aaactcggca tccggcatcc gggcgctaac gcgggaacgt gtacgttgtg
    20461 ggtaaatgtg ctggctgcgg aaatagtcat aaagtgaaat cccgatggca tcaacatcat
    20521 gaattaaatg cgccggaacc cacgattcct caatcgatac cgcttcttca tcgacatagc
    20581 gaatacgctt aagcaaaaag acatcacttc ctgcttcgac cgccagctgc tgcgcgactt
    20641 cttcgggaca tttcacgaca cgcttgttaa cccatagcgt atcgggcttt ttcccgcgca
    20701 ataccacctg ctgagaaaaa cctcgcgctt ctttcaacga gtattcgaag atgttgttga
    20761 tctgcgtgcc gtaaccgcgc gaacgcgtca ccacaccctc ttcttccagc gcctgcatcg
    20821 ccttgcgcac cgtaatgcgc gaaacgccgg ttaactgact taaatcacgc tcaccgggca
    20881 aaatattgcc atgctccagc accccgctgc gcacggcatt ttttaccgtt tcggcaaact
    20941 taatataaag cggcgtgtta tccgcagcta aaatacgctc gttcagttgg gtaatcagct
    21001 gggtatgcgc ttgttccatt tgtctttttc ctgccaggga gtctggtggg agtatatcac
    21061 tgcttcttat ttaaggcgtt tctttaatcc catcaacgaa tccctgcaac tcctccaccg
    21121 tgccattaaa cacattaaaa tccaccggac cattgatgcc atctacctgt ccacggtcgg
    21181 aatgctgcca gaagcgccag gccattccgt cattgtccgg acgacgttga taatagtgag
    21241 ccacccacca cggatattca ttgaaatagc ccgccagatt ggtgtgataa aaaacggctc
    21301 ctgagtaaat aatcggcttt tttcccgtac ttttttcgac catttttagc cactgactta
    21361 ctcgcttgcg taattctttt gccgataatt ttccccgttc ttctacgtcc agtaccgcag
    21421 ggaaatcgcc ttgtgagaaa tccaccgttt gcagaaataa tcgtgcctga accggcgctg
    21481 ctaccgacgg ggagaaataa tgatacgccc cgcgcagcag gccattttcg cggcttagtt
    21541 gccagttacg cgaaaaatac gggtccacca gcttttcgcc ttccgtcgcc ttaataaaag
    21601 caaactgtaa gcggataccg ttgtcgcgca tttttgccac ccgctgccag tcgatccgct
    21661 cctgccagcg agaaacatct attccgtgaa tggtgtaact ggcaggaatg cgaatagcga
    21721 aagatttaac cgggcgataa ccgtagaaat ggatgtagtc tgtaatctga actgctgtcg
    21781 aatagaaaaa attcaccgtc tgacgcggat aaattgcaac gatggaaatt agcccaagag
    21841 cgcataatag agaggtgagt ttttttcgac tggtaattct tagctgcatt ggtttcatcc
    21901 ctgaatgtca gtgccaaagg ctgacaataa ccaaagcagc tatagtacgg tgctcaccac
    21961 caggcgtgga agtggtgaac cggaccaata ccgtgaccaa cttccagcgt gtcggcttgg
    22021 gctaacgccg atgaaagcca gctttttgcc tcctgtacgg tgtcagccca gtttgtatgg
    22081 cgcgggcgta gtgcagccaa cgccgcagag agtgtacaac cagtgccgtg ggtgtttttg
    22141 gtcataatgc gcggtgcggt aaaccgttgt tcaccctcgc gggtaaacag ccagtccggg
    22201 ctttgctcat catccagatg accacctttc attagcactg cgccacagcc catcgccaac
    22261 agcgatcgcc cttgttccag catttcctgt tcggtgcgcg cgtgtggcgc gtcgagcaag
    22321 gcggcagctt cgggcaagtt tggcgttatt aatgaaacct gtggcaataa tcgactgcgc
    22381 agcgtagcaa ccgccgaagg tgaaagcagc gggtcgccgc tttttgccag cataacggtg
    22441 tcgagtacca cgttttggat ctgataacgt tgcaaccgtt ctgccaccgc ttcaacaata
    22501 tcggtttccg ccagcatacc gattttagtg gtatcgattc gcacatcgct gaacaccgaa
    22561 tcgagctggg cggcgacaaa atcaggctca atgcgataca ccgactgtac gccacgggta
    22621 ttttgcgcca ccagtgcagt aataactgag caaccataag cgccaagtgc cgagaaggtt
    22681 ttaagatcgg cctgaatccc cgcaccacca ctcggatcag taccggcaat cgtcagagcg
    22741 ttaattcgtt tcatgcctgc acctcctgcg tcaattgcca gagcgcatca aggaaatgtg
    22801 gaacaaaact gcctggcccc tcgcttctgg cgactgcgcg ttctccggct tgtttcatcc
    22861 agtgacaggc agatgcgaca ttttccagcg tatcgcctgg taacgcacag caggcagcga
    22921 caaccgccga taatgcacag ccagttccta ccactttggt cattaacgga tcaccaccgt
    22981 gaataccaat gatacgatgt ccatcggtaa cataatccat ctcgccagtg accacgacga
    23041 ttgcgccagt ttcccgtgcc agtgtttgtg cagcgggtat cgcgttagct gcggcgtcag
    23101 tggtatccac tccccgtccg ccattagcaa tgccagctaa tgccatgatt tccgaagcat
    23161 taccacgtat cgctgccggt ttaaaagata aaagttcatg acaaaaatgg cggcgataat
    23221 cgagcgcacc caccgctact ggatcaagcg tccagggtgt ttgagagctt tttgcttgct
    23281 caacggcagc acgcatcgcc tgagcgcgtg gctgcgtcag tgtgccaacg ttaatcaaca
    23341 aggcactggc gatagccgca aactgactgg cctcttcggt ttcgataacc atcgctggcg
    23401 atgcaccgag cgccagcaag gtattggcgg taaaggtttg caccacatca ttggtcatgc
    23461 agtgcacaag aggggaatgt tggtgaaaaa ggtgtaacgc gtgcgcagat tgcgctgaac
    23521 ccagcaggtc gacttgcata gtttgctcct gccataacgt gaagaagcaa tgacctggtg
    23581 gtccgtgact tccctacgct ggcattatcc agatcaggtg atacgggtat ttctcagcct
    23641 tcacgcagaa gggcaccccg agtcgtttgg ttgcgatgat aaatcgcaga ggaggatggt
    23701 aatgtccagc gcacgcgttg taaacgagga aaaacggcag ttttacaatc gcgttaataa
    23761 attatttgat atatgaatcc agcaccttca gaacgacatc cagatcttct tcacgtttta
    23821 gctcatcccc ctggtgaacg atgtgttccg tcagatgacc tttaatcact tcccgcatca
    23881 gaccgtttac cgcgccacgg atagcagcaa tctgttgtaa aactgcagcg cattcgtgcg
    23941 gctcgtcgag cattttcttg agcgccacga cctggccctg aatcttactg gcacgcgctt
    24001 tcagtttctg tttatcacgg attgtatgag acatggcaac acctggttaa caagaatatg
    24061 aaaaatcata gcactattaa tctactgggg ggtagtatca ggtactgggg gggagtagaa
    24121 tcagattgcc gaattaatac taagaattat tatcatgacc gaatttacaa ctcttcttca
    24181 gcaaggaaac gcctggttct tcatccccag cgccatctta cttggtgcgc ttcatggcct
    24241 ggaaccaggg cactcaaaaa cgatgatggc ggcgtttatc atcgccatca aaggcaccat
    24301 taaacaagcg gtgatgctcg gactggcagc aactatttcg cataccgcag tggtctggtt
    24361 aattgccttt ggcgggatgg tgatcagcaa gcgctttact gctcaatcag cagaaccgtg
    24421 gctccagctg atttccgcag tgatcattat tagcaccgcg ttctggatgt tctggcgtac
    24481 ctggcgcggc gaacgcaact ggctggagaa tatgcacggg catgattatg agcatcatca
    24541 tcacgatcac gaacatcacc acgaccatgg acatcatcac catcacgaac atggcgagta
    24601 tcaggatgcc catgcacgag cccatgccaa tgacattaaa cgacgctttg atggtagaga
    24661 ggtcaccaac tggcaaattt tgttatttgg cttaaccggt ggccttatcc cctgcccggc
    24721 agcaattacc gtgctgttga tatgcattca gttgaaagcc ctgacactgg gcgcaacact
    24781 ggtcgtcagt ttcagcattg gcctggcgtt aacgcttgtc accgtaggcg ttggcgcagc
    24841 aatcagcgtt cagcaggtcg caaaacgctg gagcggattt aacactctcg ctaaacgcgc
    24901 cccctatttt tccagtctgt tgattggctt agtcggtgtg tatatgggcg tacatggctt
    24961 catgggcata atgcgataac tcaatccttt aggcttgcat gttatcttca gcccaggatg
    25021 attcttaaat cagctatttc cgctgactct ctgctcgcta aggatgcttt tagggcatcc
    25081 tttcatttac actttttacg aaatcatggg atcactaaca aaatatcgct tgtcagttat
    25141 attgtatggc aggaaagata tgcgactgat attacagatc cccaaagtgg agagtttatg
    25201 accattaaaa ataagatgtt gctgggtgcg cttttgctgg ttaccagtgc cgcctgggcc
    25261 gcaccagcca ccgcgggttc gaccaatacc tcgggaattt ctaagtatga gttaagtagt
    25321 ttcattgctg actttaagca tttcaaacca ggggacaccg taccagaaat gtaccgtacc
    25381 gatgactaca acattaagca gtggcagttg cgtaacctgc ccgcgcctga tgccgggacg
    25441 cactggacct atatgggtgg cgcgtacgtg ttgatcagcg acaccgacgg taaaatcatt
    25501 aaagcctacg acggtgagat tttttatcat cgctaaaaaa agccccctca tcatgagggg
    25561 gaaatgcaga caccttgtta ttttttatta ttagccactt gctcgtcttg cttgttatta
    25621 gtcgtatttc acgttgatta atgcggttgc ctccagtgcg ccagatttaa ctttgtttgt
    25681 atcgtagacg tagtaactgg ctgttatcgg aattgaaacc gttgtatctg taagttttga
    25741 cttcgccgca acttccttta aatttgtata tcctttactg ctgttagtga tatttaaaag
    25801 tgtgactggc gaaccattac tttcaagaat aaatcctacg ccattatctt ccgcaccttt
    25861 cagtattgtg ttgctgttgg ttaacaagtc agaacttgat aaatacacct gcattttccg
    25921 tgatgtttga ttttgttgac ctaataaatt tttacaacgc agaataatat ccccttgttt
    25981 actatttatt gttgctttgt tacctgtggc tggtaattgt gaaacgggaa tactgtctaa
    26041 agtaattaat aaatcgtccg gtttgcaggt tgtggttatc gggttgtatg acaatgtcag
    26101 attaaaggaa tagacacctg cattttgtgc caatgcattt ctgtagctat ttacacatgc
    26161 atcccatgac ttgccaccta ataaacacag tagaaattgt actgcggcac tcccgcgtgt
    26221 cgatgatgaa gcactggata atgtcgcaac accattaatc atcactgaac cgccgccccc
    26281 cgcagaaaca ttcacttttg cattactggc cgcaggtgtc accgtaactg aataaccact
    26341 ggtgaaactg gtctgattat ttgacaacgt gatgttgttt ttattggtcc attcaaaatg
    26401 taaatttaat tttatggtat cgttataaag tccaacaata atatccgacg ggctcatagg
    26461 ggtgatagta tttgtactta cgcatgacga atcattaaaa ttatgctcat atgtcgccat
    26521 ttgtgtttga gtaagtgcaa aatccccctg aacaaccaag ttgtgctgaa cagataactc
    26581 actataacat gccgcatagc tcacaggcat aaccatcatc attaatataa atagcattat
    26641 gcgaatttcc atagaaccac ctgactatta ctggcaaata taatttctac tttcatcaat
    26701 ctctttaccg aaggtgattg tgcatgaaag tccttgttgc ttatcaattg ccacattaac
    26761 cgatggcggt acttcattgg tgcgaataaa taactgactt ccctggccga caacgccaat
    26821 attatgacca tggatatcat tgacttcata accaaacgtt aatgattgcc catctgctct
    26881 taacgctttt ataaaccatg gcttgcgctg atcggtatca aaattaacca gtacaaccgc
    26941 gccgcgataa ggggcggcaa ttttccggtt gccacgtaat tctgcttcgc tatcgctttg
    27001 cgacacatcc agcatcaggt gattttcccg ataaggtgtc attccgtcgt atatcaccac
    27061 tccattacgg tttgttgtgc gatatttttg cccattgaca taagcatctt taattcctgg
    27121 cgcattcatc acagcaaacg tttcggaaag acggttcgcc agattaacgc cacccgacca
    27181 ggcgacaatg ccccctgaaa cactggctcc agcctgtcga taagtactcg actgactata
    27241 actgccattc actgtcgcaa ccggcgcgtt ccaggtcaaa ttcgccccag ctgtcgtttc
    27301 atttccctga tgttgatgac tcaggttgac accataattg aactgatccc gactccctac
    27361 tgttcctgat aatcccgtat tatttgaggc aaacccctga tcatcaaacg tcgttgagtt
    27421 agacatatat atttgccgac gaggcgtcga aacgtcatca ccccaatcaa agggaatcga
    27481 tataaaaata ttaaaacgtt tctcttcatg atgattctcg tcataagcct ggcttgccgc
    27541 gagggtatag cttatccgtc gcaggttgtt ggaataactc aactgataat ccttactact
    27601 gccgctacgc ccccagtaat ctcgccataa cgtacttaat gacacagacc cccaaccttc
    27661 tggcaatgac tggctcatat tggcggaaaa gctatttttg cggccaaaat cgttctggta
    27721 ataatcggca atgtcataga catcgttttc atcacggcga taattatctt tattgtttgc
    27781 ccaaacgtga tcgttaaatg tccggtaatc acgcgacgaa taacgccagg ccgccagacc
    27841 aaaacgcgtc gacgtttggc tcacaaattt gttgtaggca atttgataac tttgcccgtc
    27901 aaacacatcg ccgttgtctt gtttactatg cgacttagtg gcatcgacgg aaatggcacc
    27961 aatgcgtgta ttccagccag cccccaaagt aaacgcgtaa taattattcg cgaccatcga
    28021 gccaccatac agcgtcaata aattattaaa accatactga taacccgcct ggacaaaatc
    28081 actttgtttg ctcgcccctt caatatggct acgacccgcc gctaaatcat atttcgacac
    28141 gccgggttgc agcatatttg gcaccgctgc ataaggcacc agataggtgg ttaccgagcc
    28201 gtccgcctct ttcacgctga catcaagatc tgctccacca ccggccaact gcaaatctgt
    28261 aatcgcgaac gggccaggag gaacctcttt ctgataaacc acaaaaccat tctgttcaat
    28321 agttaccagc gcgttactct gagcaatccc ctgcacccgt ggcgtaaaat tttgtttcga
    28381 gttaggcaac atctgcatat cacgaaacaa ccgcacacct ctgaagcgaa cagaatcaaa
    28441 aatatcgctt gatgtgtaca tatcacccac gcgaagcgtg ccgagaagtt gggcaaatcc
    28501 acgttccaga tacagggtat tgcttttcca cacccctgga ttgttatttg ttttactgaa
    28561 actggcatca gaatgcagtt gccaccccag taaatttaac ccgctgttaa aacgtacata
    28621 tgtactcttg ttattaccca acgctttata gtcgctgtaa tactgactca gataataaga
    28681 ggtataaaac gcattaatac cccgctccca gttttccggt ggaacatagc cactttccag
    28741 ttcttccacc caggcctgcg ggacactgaa atcgagacga aaaaccccga tatcccaggt
    28801 atagctccca ccctgaacaa gttgctcaaa tgttaaacat tgcttaccgc tggcgaagtt
    28861 atcgctatta atgcctaacc gcttgataac ttctcttgat aaacatgttt cttgcgggtt
    28921 gtctttaaca ataatctcat atttcccgcg ccattgctta ttgacataaa tatcgatgtc
    28981 atactgcccc ggtaagggtt gattatcatc aagacgaata tttgcaacct gctggtcttt
    29041 cattccacct atcataaaat gggtatcaaa ggtttcttca gctgcataag cttcaatgcc
    29101 gagcaataac gctacgattg ctgatgcaag tggggtcatt ctcaacatag gcagctcctg
    29161 caattaaatt ttgtcactaa tatagttgcc atggtcatcg ataatggtca gatgccagtt
    29221 atttgcatta ttacttttga cattaacact ctgactttct aagggggcaa tcataatagt
    29281 ttcataattg actttgacat tattagcttt gacatccgaa atcgtcaccc aattagctga
    29341 gtcatttttt atcaccaaac cattgccact gcgatttacc agcaattttt taaatgtcgc
    29401 tttatttacc ggagcaatac ccgctggccg gtaaaacaac ttaattctgt tttgcatcgc
    29461 aaacttcagt gcattcttac cttcttgctc tggactattt ggtggaatat ccagaacatt
    29521 cagataaaaa atgctttctt tattagtggg cagtttattc ggcataattt tgatttttac
    29581 ttgctgcccg gaatttgccc ctatttttgc cactggtggc gttaacatga aaggaacctg
    29641 aattttttct ggtggtaatg acgtatcgcc atcatcaatc cacgcctgca gcagcgaaga
    29701 acggtttccc tggttcatca actgcaccat cacttcttta ttttctgccg ggtaaataat
    29761 gcgcgtcccg tagataacaa ttccggcatg tgcaggaagg accatagaaa aaatgagtaa
    29821 agataataat cctttcattt taatgcctct taaattaaaa ggccgccatg ggatagcggc
    29881 catgtttatt acctggagaa acttacaatt ttatttatta atcctgcgcc acacgcataa
    29941 ccagagaaga taacacatca cctgattgca ctgagttatc tgtcagtttc aggtattttg
    30001 ctttaaacgg aatagcatat tgaccttccg ctgttttata actctcaatg ttaaaaggtg
    30061 cagaaacatc caggacatcg ctgttatcac ctaaatagag atagtaaccc acggtatcgt
    30121 tgctactggc tatcgcctta tcgttaccgg ttattttatc gttggtaatc aacgagagtt
    30181 ttacaccagc aacttctttc gggcagctaa tttttaacat gctgctggtt acaccgactg
    30241 catcatcata ggtagaatat ttagctttac cttcaaagac actggttggt acagtcggca
    30301 tattaatact tactgaatca ccacccgctt cgaatttaca cggagattct gcaatattcc
    30361 ccttaatagt taatgttccg gtatcaacgt ctgcagcaaa tactccagcg ctcataaaaa
    30421 aagaagaaaa gacagcggca gcaataattg aacgtttcat aatatgttcc ttaataaaat
    30481 ttatttttgg ttgttaagag tctgtatctc ttggaaacaa atttctcaca tcaaaaaagt
    30541 tgccgcaatg taaacacatt gttttattga tttaaaacaa attaaccatt gcaatataaa
    30601 tacaacaaat atttaagagt attaactatt tatcgcatct atcaattaat gtagatttat
    30661 gtaaatggta ttgttgatat caataaaaaa gccgaaatca tttatataaa tgatttcggc
    30721 tttctaaatg caattaaaat caggttgcca aattaatcgt agcgatttaa cacgattcga
    30781 cgtttgctat cgctacctgc aacaaccact tctgtcgtta cacctttgac gggcgaagaa
    30841 aacagatgac gggtgtcaac attatacgtt aactgaccac aatgctgttg aggttgacca
    30901 ttaaccatag ccatactgca tgttggggga ctgatcctgc cattaatcgc taatgtggca
    30961 gtctctgaag agaatgcggg agaagccaat ccataggcaa gaaaaataat tcctgacagc
    31021 caatacttat tcattgaacg ttatccctgt agtaaaggtt atgcctggat agaatgagtg
    31081 cataacaaac tatagctgta catccactac acagccacga aggatgataa tgaagcattg
    31141 cctgtatgat caatcgactt tgtagagttt cggacgaagg tccgcagaat attcgcagta
    31201 ttaaataagt gttcattaat gcggcaaaaa ctaatacacc gcatcaatgt aacatctctg
    31261 cggtgtatga agaataacca gaatggttaa taggcgttag accgcgcgga aggaaatctc
    31321 gcctggaatg acttcaccct gccagtagag ctgagctgca acgcggtcag ccagctggcg
    31381 gtagatagcg gtaaattcgc tctccggacg gctgataacc gttggcgtac ctttatcgag
    31441 atcctcacgt aaggagatgt gtaacggcat ctgccccagc agctgtgtat ggtatttttc
    31501 agccagtttc tctgcaccac cggtaccgaa aatcggttca tggtgaccac agttactgca
    31561 aatatgcaca ctcatgttct cgacaatacc gagcaccgga acctcgactt tctcgaacat
    31621 cacaatgcct tttttcgcat cgatcagcgc gatgtcctgc ggggtggtga ccacgactgc
    31681 accggttact ggaatgtttt gcgccagcgt caattgaatg tcaccggtgc ctggcggcat
    31741 atcaagcacc agatagtcga gatccggcca caaggtttcc tgcaacatct gcattaacgc
    31801 cttgctcgcc atcggtccac gccacaccat cgcattgtcg tcagtgacca gataaccaat
    31861 tgaattggtt gccaggccat gagacataat cggtgccata tgggtaccgt ccggcgaagt
    31921 tggacgctga ttttctgcgc ccaacattgt tgggattgat gggccgtaga tatcggcgtc
    31981 cagaatgccg actttcgccc cttctgccgc cagcgccagt gccaggttta ccgccgtgga
    32041 cgatttaccc acgccgcctt taccggaact caccgcgata atgttcttca caccgttaat
    32101 tcccggctga ttcttcacgc gtttcagagt ggctatgtta tgcgacagtt tccagtcgat
    32161 agctttcgcc ccggtgatgc gcagcagttc ggcgctacat tgctctttta actcttcgaa
    32221 cgcgctatgc cagacaaacg gcataaccag ttccacatgc aacgtgtcgt ccatccaggc
    32281 gacatggtgc aacgctttca gcgtggtgag gttatgcttc agggttgggt gctgaaaatt
    32341 ggccagtgtc ccggcgacca ttgcgcgcaa ggcttctggt gatttggcct gggattgttc
    32401 gttcatcccg actccttttt tgtatagata aaccatcagc tgatagttta cctgaagaat
    32461 atagagaagt acttacttaa cattttccca tttggtacta tctaacccct tttcactatt
    32521 aagaagtaat gcctactatg actcaagtcg cgaagaaaat tctggtgacg tgcgcactgc
    32581 cgtacgctaa cggctcaatc cacctcggcc atatgctgga gcacatccag gctgatgtct
    32641 gggtccgtta ccagcgaatg cgcggccacg aggtcaactt catctgcgcc gacgatgccc
    32701 acggtacacc gatcatgctg aaagctcagc agcttggtat caccccggag cagatgattg
    32761 gcgaaatgag tcaggagcat cagactgatt tcgcaggctt taacatcagc tatgacaact
    32821 atcactcgac gcacagcgaa gagaaccgcc agttgtcaga acttatctac tctcgcctga
    32881 aagagaatgg ttttattaaa aaccgcacca tctctcagct gtacgatccg gaaaaaggca
    32941 tgttcctgcc ggaccgtttt gtgaaaggca cctgcccgaa atgtaaatcc ccggatcaat
    33001 acggcgataa ctgcgaagtc tgcggcgcga cctacagccc gactgaattg atcgagccga
    33061 aatcggtggt ttctggcgct acgccggtaa tgcgtgattc tgaacacttc ttctttgatc
    33121 tgccctcttt cagcgaaatg ttgcaggcat ggacccgcag cggtgcgttg caggagcagg
    33181 tggcaaataa aatgcaggag tggtttgaat ccggcctgca acagtgggat atctcccgcg
    33241 acgcgccata ctttggtttt gaaattccga acgcgccggg caaatatttc tacgtctggc
    33301 tggacgcacc gattggctac atgggttctt tcaagaatct gtgcgacaag cgcggcgaca
    33361 gcgtaagctt cgatgaatac tggaagaaag actccaccgc cgagctgtac cacttcatcg
    33421 gtaaagatat cgtttacttc cacagcctgt tctggcctgc catgctggaa ggcagcaact
    33481 tccgcaagcc gaccaacctg tttgttcatg gctatgtgac ggtgaacggc gcgaagatgt
    33541 ccaagtctcg cggcaccttt attaaagcca gcacctggct gaatcatttt gacgctgaca
    33601 gcctgcgtta ctactacact gcgaaactct cttcgcgcat tgatgatatc gatctcaacc
    33661 tggaggattt cgttcagcgc gtgaatgccg atatcgttaa caaagtggtt aacctggcct
    33721 cccgtaacgc gggctttatc aacaaacgtt ttgacggcgt gctggcaaac gaactggctg
    33781 acccgcagtt gtacaaaacc ttcactgatg ccgctgaagt gattggtgaa gcgtgggaaa
    33841 gccgtgaatt tggtaaagct gtgcgcgaaa tcatggcgct ggctgatctg gctaaccgct
    33901 atgtcgatga acaggctccg tgggtagtcg caaaacagga aggtcgcgat gctgacctgc
    33961 aggcgatttg ctcaatgggc atcaacctgt tccgcgtgct gatgacttac ctgaagccgg
    34021 tactgccgaa actgaccgag cgtgcagaag ccttcctcaa tacggaactg acctgggatg
    34081 gtatccagca accgctgctg ggccacaaag tgaatccgtt caaggcgctg tataaccgca
    34141 tcgatatgaa acaggttgaa gctctggtgg aagcctctaa agaagaagtg aaagcagctg
    34201 ccgcgccagt tactggccca ctggcagatg atccgattca ggaaaccatc acctttgacg
    34261 acttcgccaa agttgacctg cgcgtagcgc tgatcgaaaa cgcagagttt gttgaaggtt
    34321 ctgacaaact gctgcgcctg acactggatc tcggcggtga aaaacgcaat gtcttctccg
    34381 gtattcgttc tgcctacccg gatccgcagg cactgattgg tcgtcacacc attatggtgg
    34441 ctaacctggc accacgtaaa atgcgctttg gaatctccga aggcatggtg atggctgccg
    34501 gtccaggcgg gaaagatatc ttcctgctaa gcccggatgc tggtgctaaa ccgggtcatc
    34561 aggtgaaata atcccccttc aaggcgctgc atcgacagcg ccttttcttt ataaattcct
    34621 aaagttgttt tcttgcgatt ttgtctctct ctaacccgca taaatactgg tagcatctgc
    34681 attcaactgg ataaaattac agggatgcag aatgagacac tttatctatc aggacgaaaa
    34741 atcacataaa ttctgggcgg tggagcaaca gggaaacgag ttgcatatca gttggggaaa
    34801 agttggcacc aaagggcaaa gtcagataaa aagtttttca gatgctgcgg cagcggaaaa
    34861 agcggaactt aagctgattg cggagaaggt gaagaagggg tatgtggagc aagcgaagga
    34921 taattctttg caaccttccc aaacggtaac gggctctctc aaggtagcgg acttatccac
    34981 cattattcag gaacaaccct ctttcgtagc agaaacccgt gcgcctgaca aaaatacaga
    35041 tgctgtttta ccgtggctgg cgaaagatat tgctgtcgtt tttccgcccg aagttgtaca
    35101 caccacgtta agtcatcgcc gctttcccgg agttcctgtt cagcaagcag acaaattgac
    35161 ccaattacgt cgcttagcct gtagtgtgtc gcaacgggat aataaaacag ccacatttga
    35221 cttcagcgcc tgttctttag aatggcaaaa caccgtcgcc caggcgatca gtcagatcga
    35281 cggcctgaaa acaacacagt taccatcacc agtaatggct gtactcacgg cacttgaaat
    35341 gaaatgcaca agatataaag tgcgtgagga tgttatggat cagatcgtcc aggaagtcgg
    35401 tctggaatat gctactgatg taataataca ccttcaacag attgatattg aatgggatta
    35461 tgcgaataat gtcattatta ttctgccgtc tggcattgca cctagctact tggagcaata
    35521 ttccagattt gaattacgcc tacgtaaaca tttatcactg acggaagagt ctctctggca
    35581 aaaatgtgca caaaaactta ttgccgcaat tccacatatt ccagaatggc ggcaaccatt
    35641 aattgctttg ttattacccg aaaaaccaga aattgcacat gaaattgccc agcgtctact
    35701 ggggcaaaaa aaattaccct cgcttgagtg gttaaaaata gtggcgactg atgagcacat
    35761 tcttgcctca ttagaaaaat atcacgaacc atatgccatt tttgatgatt actattgtgg
    35821 tgcgatatgg tcagccaccg tattacagga gcaaggtgtt gcagccctgc cccgatttgc
    35881 tccctatgcc gcaagtgact actgcgccga tgtgttgcgt catatcaatc atccgttcgc
    35941 attgacactg cttatacgtg tagccgggca aactaaacgc tgtcacgatc ggatgacgaa
    36001 agccattgct gcgttcccac atgcagcaat ggcggcactg acggaacttc ttgggcaaaa
    36061 agaagagaac agttggcgca ttatgctaat gacaatgctt atctcacaac cagcactggc
    36121 agaacaggtc attccctggc tctcgacacc cgcagttgcc gtactgaaat catgccagca
    36181 acaactgaca cagccctcaa accatgccag cgccgatcta ctgccagccg tagtagtctc
    36241 ccctccctgg ctttcgaaaa agaaaaaatc gccgattccg gtgctggatt tagcgccatt
    36301 aggcattgag ccaatctgtt atctgacaga agaaatcagt aatcaacttt tggcgaaata
    36361 tatctggtat tcaaaacaca tcacggttag ccatgaagaa agtactacca acctgttggc
    36421 aaggatgggt tttcaacgac ggatcgctgg tacatatatt aaagctcccg aagcggtagt
    36481 tgaggcatgg ctaaatgaag attattcaac cttactaagt gaatttaagg tgtttcattc
    36541 acctaccggg cattattggc agttggggat tttgacaaca ttgccgctgg agaaagcagt
    36601 aaaagcatgg aatgccctta ccctatctcc acataccgat accgaatact ccatgttaca
    36661 ttttggactc aaagggttac ctgggttagt aaactcactt gcacgctatc cacaagaagc
    36721 cttgcccatc acgaattact tcgcagcgag tgagctggct cctgccgtcg cccgtgcctt
    36781 caacaaactg aaaacgctac gcgaaaacgc ccgtagctgg ctgttgaaat acccggaaca
    36841 tgcccttacc ggcctgctgc ctgcggcgct cggcaaagcc ggtgaagcac aggataacgc
    36901 ccgcgctgcc ttgcgtatgc ttaccgaaaa cggtcatcag ccattactgc aagaaatcgc
    36961 ccgacgttat aaccagccgg aagtaaccga tgcggtgaac gctctgcttg cgctcgatcc
    37021 cttagataat cacccgacaa aaatccccac tcttccggcc ttttatcagc catcgctctg
    37081 gacgcgcccg gtattaaaag caaatgccca atcactgcca gatagcgccc tcctccacct
    37141 cggtgaaatg ctccgcttcc ctcaggaaga ggctctgtat ccgggattat tgcaggtgaa
    37201 agacgtctgt tccgccgact cactggcggg atttgcctgg gatctgttta ccgcctggca
    37261 gaccgctggc gcgccgtcga aagagagttg ggcgttcact gcgttaggcg ttctcggtaa
    37321 cgatgacacc gcccgcaaac tgacgccatt aatacgcgcc tggcctggtg aatcccagca
    37381 taaacgcgcc accgttgggt tggatattct cgctgctatc ggtagtgata tcgcccttat
    37441 gcagcttaac ggcatcgccc agaaactgaa attcaaagca ttacaggagc gggcaaaaga
    37501 aaaaattgcc gacattgccg agagccgcga actcacggtg gcggagcttg aagatcggtt
    37561 agcaccggat ctcggtctgg atgataacgg ttcgctgctg ctggattttg gcccacggca
    37621 gttcaccgtc agctttgatg aaaccttaaa accgtttgtg cgtgatgttt ccggcagccg
    37681 cctgaaagac ctgcccaaac cgaacaaaag cgatgatgaa acgcgggcga acgatgcggt
    37741 taaccgctac aaattgctga aaaaagatgc gcgtaccatc gccgcccagc aggtagcaag
    37801 gctggaatcc gccatgtgcc tgcgccgccg ctggtcgctg gaaaacttcc agctcttcct
    37861 ggttgagcat ccgctggttc gtcacttaac ccgccgtctg atttggggcg tttatagcgc
    37921 cgaaaaccag ctactggctt gctttcgcgt agcagaagat aacagctcca gcaccgctga
    37981 cgatgatctt ttcaccctgc cggaaggcga tatctctatc ggcactcctc acgttctgga
    38041 aatatcacca acggatgctg ccgcctttgg tcagcttttt gccgcctacg aactgctacc
    38101 accgttccgc cagctcgacc gtaacagcta cgccctgaca gaagccgagc gcaatgccag
    38161 tgaactgacc cgctgggcag gcagaaaatg cccgagtggt cgggtcatgg ggctggcgaa
    38221 taaaggctgg ataaagggcg aaccacagga tggaggctgg atcggatgga tgatcaaacc
    38281 tttgggtcgc tggtcgttaa tcatggaaat cgatgaaggc tttgcggtag gcatgtcgcc
    38341 agccgaactc agcgctgagc agctcttaag caagctgtgg ctatgggaag gcaaagcaga
    38401 aagatatggc tgggggagta attcaacaca ggaagcgcag ttctccgtaa tcgatgccat
    38461 caccgccagc gagctaatta acgatattga agccctgttt gaataaggaa agagcatgga
    38521 caaggaatta ccgtggctgg cggataacgc ccaactggaa ctgaaatata aaaaaggcaa
    38581 aacgccgctc agtcatcgtc gctggccggg cgaaccagtg tccgttatca ctggaagtct
    38641 catccagaca ttgggtgatg aattgctaca aaaagctgag aagaaaaaaa acattgtctg
    38701 gcgttatgag aatttttcac tggagtggca gtccgccatc acgcaggcca tcaacttgat
    38761 cggcgaacac aaaccctcaa tcccggcccg gacaatggcg gcgctagcct gtatcgcgca
    38821 aaatgacagc caacagttgc tcgacgaaat cgtccaacaa gaggggctgg aatatgcgac
    38881 tgaggtggtg attgcacgcc agtttattgc gcggtgttat gagagtgatc ctctggtagt
    38941 gacattgcag tatcaggacg aggattatgg ctatggttat cgctcagaaa cctataacga
    39001 attcgatctc cgactgcgta agcatctctc tctggcagag gaaagctgct ggcagcgttg
    39061 cgccgacaaa ctcattgccg cactaccagg aataaccaaa gttcgccgcc cttttattgc
    39121 gctgatcctc ccggaaaaac cagaaatagc caatgagttg gtaggccttg aatgcccgcg
    39181 aactcatttt cattctaagg agtggttaaa agttgttgct aatgacccca cagcggtgag
    39241 aaaactcgaa cactactgga gccaggatat atttagcgat cgagaagcca gctacatgtc
    39301 gcatgaaaac cacttcggct acgcggcctg cgccgccctt ttgcgcgaac aaggactggc
    39361 agccattccg cgcctcgcga tgtatgccca taaagaagat tgcggcagtc tgctggtaca
    39421 aattaaccat ccgcaagtca tccgcacctt gctactggtg gctgataaaa acaaacccag
    39481 cctgcaacgt gtagctaaat accataaaaa cttcccccat gcgacgctcg ccgcactggc
    39541 agaactgctg gcgttaacag aaccaccagc ccgccctggt tatccaatca tcgaagacaa
    39601 aaagctgcct gcacagcaaa aagcacgcga tgaatactgg cgtacgctgt tacaaacgct
    39661 gatggcatcg cagccacaac tggcagcaga agtgatgccg tggttaagta ctcaacccca
    39721 gtcagtgctg aagagttatt tatcggcacc gcccaaaccg gttattgatg gcaccgataa
    39781 cagcaatctg ccagaaatcc tcgtttcacc accgtggcgt agtaagaaaa aaatgacagc
    39841 tccacgtctt gatttggcac cgctcgaatt aactccgcaa gtttactggc aaccaggcga
    39901 acaagagagg cttgccgcca ctgagcctgc ccgttatttc agcacggaat ctcttgcgca
    39961 acgcatggaa caaaaaagtg gacgagttgt attacaggaa ctgggttttg gggatgatgt
    40021 atggctgttt ctgaattata tactccccgg aaaactggat gctgcacgca attcactctt
    40081 tgttcagtgg cattactacc aggggcgggt tgaagagatc ctgaatggct ggaactcccc
    40141 ggaagcacaa ttagcagaac aggcgctccg cagcggtcac atagaagcgt taattaacat
    40201 atgggaaaat gacaactact cacattatcg tccggaaaag agtgtctgga acctgtattt
    40261 attggcacag ttgccgcgtg agatggcttt gaccttctgg ctgcgtgtca atgagaaaaa
    40321 gcatctgttc gcgggtgagg actattttct cagtatcctc ggattggatg cgctaccagg
    40381 tctgctgttg gctttttcac atcgtccaaa agaaacattt ccgttaattt taaattttgg
    40441 cgcaacagaa ctggcgctgc ctgttgccca cgtctggcga cgtttcgcgg cgcagcgtga
    40501 tctggctcgc cagtggattt tacaatggcc ggaacatacg gctagtgcac ttatccctct
    40561 tgtctttacc aaacccagcg ataatagcga agccgcatta cttgccctgc gtttactgta
    40621 cgaacaggga catggcgaat tgctacaaac cgtggcaaac cgctggcagc gtacagatgt
    40681 atggtctgcc ctggagcagt tgcttaaaca gggtccaatg gacatttacc cggcacgcat
    40741 tccaaaagcc cctgatttct ggcatccggc aatgtggtcc aggcctcgac ttatcactaa
    40801 taatcagcct gttaccggtg acgctctgga aattatcggc gaaatgctgc gctttaccca
    40861 ggggggacgt ttttatagcg ggctggaaca actgaaaacg ttctgccagc cacaaacgct
    40921 ggcagctttt gcctgggatc tcttcactgc gtggcaacaa gctggtgccc ccgcaaaaga
    40981 caactgggca tttctggcgt taagtctctt tggtgacgaa agcacggcac gggatctgac
    41041 gacacagatc ctcgcctggc cacaagaagg caaatctgcc cgtgctgtca gcggcctgaa
    41101 catccttacc ctgatgaata atgatatggc gctgatacag ctgcatcata tatcgcaacg
    41161 ggctaaatcc cgccccttac gtgataacgc ggcggaattt cttcaggtgg tcgcagaaaa
    41221 tcgcgggcta agccaggaag agctagcgga cagattagtc ccaaccctgg gccttgatga
    41281 tccgcaggcg ttgagttttg attttggtcc ccggcagttt accgttcgct tcgatgaaaa
    41341 cctcaacccg gttatctttg atcagcaaaa cgttcgccag aaaagcgttc cccgtttgcg
    41401 cgccgatgac gatcaactga aagcgcacga ggcactggcc cgactaaaag ggctaaaaaa
    41461 agatgctact caggtgagca aaaacctgct cccgcgtctt gaagctgccc tacgtaccac
    41521 ccgacgctgg tcgctggcag attttcattc tctgtttgtt aatcatccct ttacccgtct
    41581 ggttacccag cgattaatat gggggggtta tccggcaaat gaaccgcgtc gtttactcaa
    41641 cgcctttcgt gtggccgcag agggggagtt ctgcaatgcg caagatgagc caattgacct
    41701 gcctgcggac gctctgattg gcattgccca cccgttagaa atggcagtag aaatgcgcag
    41761 tgaatttgca cagctttttg ccgattacga aattatgccg ccttttcgcc agttgtcgcg
    41821 ccgcacggtg ctgctcacac ctgacgagtc aaccagtaac agcctgactc gctgggaagg
    41881 taaatccgct accgttgggc aacttatggg aatgcgatac aaaggctggg agtcaggcta
    41941 tgaggacaca tttgtctatg acctgggcga gtaccggctg gtccttaagt tttcacccgg
    42001 ttttaaccac tacaatgttg atagcaaagc gttaatgagc tgccgttctc ttcgagtgta
    42061 ccgtgacaat aaatccgtca cttttgccga acttgatgtg tttgatttga gtgaggcgtt
    42121 aagcgcacct gacgtcattt tccattaaaa cacagcgggc agtgatgcga ctgcccgtta
    42181 tctacacgac ttaccagcgg ggaaagcgat gatcgtgcaa aaagagctgg ttgctattta
    42241 cgattatgag gtccctgtac ctgaagatcc gttttccttc agacttgaga tccataaatg
    42301 ctctgaatta tttacaggtt ccgtctatcg actggagcga ttccggctac gtccaacatt
    42361 tcatcaacgt gatcgagaag atgctgaccc gctaataaat gatgcgttga tttatataag
    42421 agatgagtgt attgatgagc ggaaattacg aggtgaatca cctgaaactg taatagcaat
    42481 ttttaatcgt gaactacaga atatattcaa ccaagaaata gaataatata ctctaaataa
    42541 ttcaaattgg tccgatccgg cgcaacgtcc caatggcctg gattataaat ctcattatct
    42601 taattgcaac ggggtccagc cgtggttata attcgttcgt tggaacacga tgttgcacag
    42661 gctgtggtgt taggcctgaa aatagtaaat aaaagaacct gcctcaccag caggtttttt
    42721 tatttactgt gatctgcttt ccagatattt ttcgctcaaa caactaatgc gccaaacatt
    42781 tattgcgcgt aaaatatcgt ttatttcatt aatacatttc agggatgaat atatgtcacc
    42841 gcagaataat catctgcagc gtccgcctgc tgctgtgtta tacgccgatg aactggcaaa
    42901 attaaaacaa aatgataacg caccttgccc gcccggttgg cagttaagtt tgcctgcggc
    42961 ccgtgctttt atccttggcg acgaagcgca aaatatcagc cgtaaagtgg tgattagccc
    43021 ctccgctgtc gaacgtatgt tagtcactct tgctaccggc cgcggtttga tgttggtggg
    43081 ggaaccgggt accgcaaaat ctcttctttc tgaattactg gcaaccgcta ttagcggcga
    43141 tgccgggtta accatccagg gcggggcatc taccaccgaa gatcaaatca agtatggctg
    43201 gaactacgcc ctgcttatca atcatggtcc gtcaacggaa gcgctggtcc ctgccccgct
    43261 ttatcaggga atgcgcgacg gcaaaatcgt ccgtttcgaa gagataacgc gtacaccgct
    43321 ggaagtgcag gactgtctgt taggtatgct ttctgacagg gtgatgacgg tgccggaact
    43381 cactggtgaa gccagtcagc tctatgcgcg agaaggcttt aatattattg ccactgccaa
    43441 tacccgcgat cgcggcgtca atgaaatgag tgctgcgcta aagcgtcgct tcgattttga
    43501 aacggttttt ccgattatgg atttcgccca ggagttggaa ctggtcgcca gtgcttcggc
    43561 gcgtttgctg gcccatagcg gtattccgca taaagtgcct gacgcggtac tggaattact
    43621 ggtccgcacc ttccgcgatc tgcgtgccaa cggcgaaaag aaaacgtcaa tggatacact
    43681 gacagcgatt atgtccaccg ctgaagccgt gaacgtggcc catgctgtgg gcgtccgcgc
    43741 ctggttttta gcgaatcgcg cgggggagcc tgccgacctg gtggaatgta ttgccggaac
    43801 catcgtcaaa gataacgaag aagatcgcgc gcgtctgcgc cgttacttcg aacagcgtgt
    43861 cgtcacacat aaagaagctc actggcaggc ttattatcaa gcccgccacc gcctgccgtg
    43921 aggaaagatg catgagcgag ccgttaattg tcggcatccg gcatcatagt ccggcctgcg
    43981 cccggctggt gaaatcgtta atcgaaagcc agcggccacg atacgtgttg attgaaggcc
    44041 cggctgattt taatgaccgg gtagacgaac tgtttttagc ccaccagctt ccggtagcta
    44101 tttacagtta ttgccagtat caggacggtg cagcccccgg gcgtggtgcc tggacgccat
    44161 ttgctgaatt ttcgccggag tggcaggcgc tacaagccgc acgtcgcatt cagacacaaa
    44221 cttacttcat cgatttgcct tgctgggcgc agagtgaaga agaggacgat tcgcctgata
    44281 cgcaagatga aagccaggcc ttactgctgc gtgccacccg catggataac agcgataccc
    44341 tgtgggatca cttgttcgaa gatgaaagcc agcaaactgc attaccctct gcgctggcgc
    44401 actattttgc ccaactgcgg ggcgacgcct ccggcgatgc gctcaatcgt cagcgcgaag
    44461 cctttatggc ccgctggatt ggatgggcga tgcagcaaaa taatggcgac gtgttagttg
    44521 tctgcggtgg ctggcacgct ccggcactgg caaagatgtg gcgcgaatgc cctcagaaaa
    44581 ttaacaagcc agaattgccc tcgctggcag atgccgttac aggttgttat ctcacaccct
    44641 acagtgaaaa gcgccttgat gtgctggcag gatacctttc aggaatgcct gccccggtat
    44701 ggcaaaactg gtgctggcag tggggcttgc agaaggccgg tgaacaactg ctaaaaacta
    44761 tccttacccg tttgcgccag cacaaattgc ccgcttctac cgcggatatg gctgccgctc
    44821 atctgcatgc gatggcgctg gcacagttgc gcggtcatac actaccgtta cgcactaact
    44881 ggctggatgc catagcaggc tcgctgatta aagaagccct gaacgcgccg ttgccgtgga
    44941 gctatcgcgg cgttattcat cccgataccg atccgattct gctaacgttg atagacacat
    45001 tagcgggtga cggattcggt aaacttgccc cttctacgcc acaaccgcct ctgccaaaag
    45061 atgtcacctg cgaactggaa cgtaccgcaa tctcccttcc ggcggagctt accttaaatc
    45121 gctttacccc cgatgggctg gcgcaaagtc aggtgttaca tcggctggca atactggaga
    45181 tccctgggat tgtacgccag cagggaagta cactgacact tgcaggcaac ggtgaagaac
    45241 gctggaaatt aacccgcccg cttagccagc atgcggcatt gattgaggcc gcctgttttg
    45301 gtgccacact ccaggaagcc gcacgcaata aattagaagc cgatatgctg gacgcgggcg
    45361 gaatcggcag tatcaccaca tgtcttagcc aggcggcgtt agcgggtctg gcgtccttca
    45421 gtcaacaatt actggagcaa ctcacactat taatcgccca ggaaaatcaa tttgccgaaa
    45481 tgggccaggc gctggaagtg ctatatgcct tatggcggct ggatgaaatt agcggtatgc
    45541 aaggcgcgca gatattacaa acgacgttat gcgcggctat cgatcgcacg ctgtggctgt
    45601 gtgaatctaa cggcagaccg gatgaaaagg agtttcacgc tcacctgcat agctggcaag
    45661 cgctttgcca tatcctgcgc gatctacata gcggcgttaa tttacccggc gtttctcttt
    45721 ctgcggcggt agccttactg gagcgacgca gtcaggcgat tcatgccccg gcgctggatc
    45781 gcggcgcggc tcttggcgca ctaatgcgtc tggaacatcc caacgccagt gccgaagcgg
    45841 cgctgacgat gctggcgcag ttatccccgg cacaatccgg tgaggcgctg cacggtttgc
    45901 tggcattagc ccgtcatcaa ctggcctgtc aacctgcatt tatcgccggt ttcagcagtc
    45961 atttaaatca actaagtgac gacgatttta ttaacgccct gcccgattta cgcgcggcaa
    46021 tggcctggct accgccacga gaacgcggga cgctggcgca tcaggtgctt gagcattacc
    46081 agcttgcgca gcttcctgtt tcagcgctgc aaatgccgtt gcattgtcca ccacaggcca
    46141 ttgcacatca tcaacaactc gaacagcagg cactggcatc gctgcaacac tggggagttt
    46201 tccatgtctg aactgaacga tcttctgacc acccgtgagc tacaacgctg gcgattaatt
    46261 cttggcgaag cggcagaaac gacgctttgt gggctggatg acaacgcccg gcagatagac
    46321 cacgcgctgg aatggctgta tgggcgcgat cctgaacggc tccagcgtgg tgaacgctcc
    46381 ggtggattag gtggctcaaa tctcaccacc cctgagtgga tcaacagtat tcacacgctg
    46441 tttccgcaac aggtgattga gcggctggaa agcgatgccg tactgcgcta tggcattgaa
    46501 gatgtggtga cgaatctcga cgtgctggaa cgtatgcagc cttctgaaag cctgctacgc
    46561 gccgttttgc ataccaaaca tctgatgaac cccgaagtac tggctaccgc ccgccggata
    46621 gtgcgccagg ttgttgaaga aattatggct cgactggcaa aggaagttcg tcaggctttt
    46681 tctggtgtcc gcgatcgccg tcgccgctca tctattccac tggcgcgaaa ctttgatttc
    46741 aaaagtactc tacgcgccaa cctgcaacac tggcacccac aacacggcaa gttgtatatc
    46801 gaatcccccc gctttaacag ccgcattaaa cgccaaagcg aacaatggca actggtctta
    46861 ctggttgatc aaagcggctc gatggtcgat tcggtgatcc actctgcggt gatggcggcc
    46921 tgtttatggc agttacccgg cattcgtacc catctggtcg cttttgacac cagtgtggtt
    46981 gatctcacgg cagacgttgc cgatccggta gagttattaa tgaaagtgca attaggcggc
    47041 ggaaccaata tcgccagtgc cgtggagtat ggtcggcaac ttattgaaca accagcgaaa
    47101 agcgtcatta tcctcgtgag cgatttttac gaagggggtt catcatcatt actgacgcat
    47161 caggtgaaaa agtgtgtcca gagcggcatc aaagtgctgg gactggcagc gctcgatagc
    47221 acagcaacac cttgctatga ccacgatacg gcccaggcgc tggtaaatgt cggcgcacaa
    47281 atagccgcca tgacaccggg cgagctggca tcatggcttg cggagaatct tcagtcatga
    47341 attcactacg tccggaatta ttagaactga caccgcaggc cctgacggcg ttaagcaatg
    47401 ccggttttgt taagcgcagt cttaaggaac tggaaaatgg caacgtcccg gaaatcagcc
    47461 atgagaacgg cgctttaatc gccaccttca gtgacggtgt ccgtacccag ctggcgaacg
    47521 gccaggcact gaaagaggct cagtgcagct gcggggccag cggtatgtgc cgtcatcacg
    47581 tgatgctggt gttaagttat caacgacttt gtgctaccgc ccagcctacg ggaaaagaag
    47641 aggaatggga tccggcaatc tggctggaag aactggctac ccttcccgat gccacccgca
    47701 aacgcgcaca ggcgctggtc gctaaaggca tcaccattga gttgttctgt gcgccgggtg
    47761 aaattccctc tgcccgctta ccgatgagcg atgtgcgttt ttattcccgc agcagtattc
    47821 gtttcgcccg ttgtgattgt attgaaggca cactttgcga acatgtcgta ctggctgtgc
    47881 aggccttcgt cgaggccaaa actcagcaag cggaatttaa ccatttgatc tggcagatgc
    47941 gcagcgaaca cgtcacatca tctgacgatc cgtttgccag cgaagaaggc aaaacgtgtc
    48001 gtcaatatgt tcagcaatta agccaggcat tatggctgag cggcatcagc cagccgctta
    48061 ttcactacga ggccgctttc agccgcgcgc agcaagcggc ggaacgctgc aactggcgat
    48121 gggtgagtga atcgctacgg caactgcgcg ccagcgttga tgccttccac gcccgcgcaa
    48181 gccattatca tgccggagaa tgcttgtgtc agcttgcggc attaaacagt cgattaaatt
    48241 gcgcacacga aatggcgcag cgcgacagtg ttggtgaaat tcctcccatg ccgtggcgca
    48301 cggtcgttgg cgcaggcatt gccggagaag caaagcttga tcatctgcgg ctggtgtctt
    48361 taggtatgcg ttgctggcag gatattgagc attatggttt acgcatctgg tttaccgatc
    48421 ccgacaccgg cagtattttg cacctttcgc gcagttggcc gcgaagcgaa caggaaaact
    48481 caccggcagc tacgcgtcgg ctgtttagtt ttcaggctgg cgcactggcg ggtgggcaaa
    48541 ttgtttcaca agcagcaaaa cgcagtgccg atggcgagct gctgttagct acccgcaacc
    48601 gcttaagcag cgttgtgccg ctgtcgcctg atgcctggca aatgttgagc gcgccgttac
    48661 gccagccggg cattgtggct ttgcgggaat atttacgcca gcgtcccccc gcctgcatac
    48721 ggcctcttaa tcaggtcgat aacttattta ttctgccggt cgctgagtgt atttcgctcg
    48781 gttgggatag cagccgccag acgctggatg cgcaggtcat tagcggcgaa ggtgaagata
    48841 atctgctgac gttatcactg ccagcctcag ccagcgcgcc ttatgccgtt gaacgcatgg
    48901 cggcgctttt gcaacaaaca gaggaccccg tgtgtctggt ttctggcttt gtcagttttg
    48961 tagaggggca attgacactg gaaccacagg taatgatgac aaagactcgt gcctgggcgc
    49021 tggacgctga aactgcgcct gtggcaccgc taccttctgc cagcgttttg cctgtgccgt
    49081 ctactgctca tcagttgctg atacgctgcc aggcgttact tattcaactg ctccataacg
    49141 gctggcgcta tcaggaacaa agtgctattg gtcaggcaga gttgctggcg aatgacctca
    49201 ccgccgtggg tttttatcgg ctggcacatg tgttgggaca atttcgtaat acagaaagcg
    49261 aggcacgggt agaagcaatg aataacgttg ttttgctttg cgaacaatta ttccccatgc
    49321 ttcagcaaca aggatgaaat agtgcttttt actaagagtt ctactccagt tccggactgc
    49381 tcacgccacg gtattaggca tatcctatat agcccctggt gagagtcacc agttccttga
    49441 ttaaataaaa tggagtttta catgaaggct ttcaataagc tgttttccct tgttgttgca
    49501 tctgttctgg ttttctctct tgctggctgc ggtgacaaag aagaatcgaa gaaattcagc
    49561 gccaatctga acggcactga aattgccatt acctatgtct acaaaggtga caaggtgctt
    49621 aagcaatctt ctgaaaccaa aattcaattt gcctccatag gtgctaccac caaagaagat
    49681 gctgccaaga cacttgagcc gttaagcgcc aaatacaaaa acatcgcggg tgttgaagaa
    49741 aaattaacct ataccgatac ctacgcgcag gaaaacgtga ctatcgatat ggaaaaagtg
    49801 gattttaaag ccctgcaggg tatttcagga atcaacgttt ctgctgaaga tgccaaaaaa
    49861 ggtatcacta tggcgcaaat ggaactggtg atgaaagccg ctggttttaa agaagtgaaa
    49921 taatctgtcg gcggccatgt ttcgcatggc cgccataccc gtcttagctt ttcttcacat
    49981 gctggcgcgc tgccagtcca cgcagaaaat aacgtaaaaa ttgatcgccg cattcgcgga
    50041 agtttttatg atccggtgca cgcatcatcg ccgtaatttc cggcatcgaa acgcggaact
    50101 gctgttcggt gaggatcgcc agaatgtcat cggttttcag cgaaaacgcg atgcgtaatt
    50161 ttttcagcac gatgttgtta ttaatgcgac gttccggctc cagtgccgga gcagactcat
    50221 ccttgccgcg tttttcataa atcaggccat tgaggaatga cgacaaaaca atgtccggac
    50281 aacgctgaaa accctcttcg tcttctttac gtagccagac ggcgatctgt tccgcggtgg
    50341 cttcgacatt acccagcgcc agaatacgca ccaggtcatt attattggct ttcaaaatgt
    50401 agcgcacgct gcgcagaata tcgttactta gcatgaggcc ttcaggtgtt gatgaggcaa
    50461 aaagccattt tagcagtctt ttacaggcca atcgcctctt ttaagctttt cagataacgg
    50521 cggctgaccg gcacggttaa gccattacgc aaaatcaact cggcctggcc gttatcttcc
    50581 agacgaatct cctgtaaatg cgcgaggtta accagatact gacgatggca gcgcagtagt
    50641 ggtgtacgac tttccagggt acgtaatgtc aattcggtaa agccctcttt cccttcgtgg
    50701 ctggtaacgt agacaccgct catccgactg ctgacaaatg ccacatcttt catttgcagc
    50761 aaataaatcc gactatgccc agtacaaggg ataaatttca gcgcctgttg attttctggt
    50821 aacagcgaaa catcctgctt gctgcgttcc tgccgcaaac gcgccagcgt tttctccagt
    50881 cgcgcttcat caattggctt cagcagataa tcaaaggcgt gttcttcaaa ggctttaatg
    50941 gcgtattcgt caaacgcggt gagaaaaaca atatacggac gatgttccgg gtcgagcatc
    51001 cccaccattt ccagaccact gatgcgcggc atctggatat cgagaaacag cacatccggg
    51061 cgcagtttat gcaccgcgcc gatcccttcc acggcgtttg aacactcacc aacgatttca
    51121 atatcgctct gctcctgcaa aaatacgcgc aggttctccc gtgctaacgg ttcatcatcg
    51181 acaattaaga ctttaatcat gcctcgtccc tccatggtag tcgtaacgtt attcgggtgt
    51241 aactatcagg ctcacaggcg acgcttatcc catagtcatc gccaaaccgt tcacgtaaac
    51301 gcttatccac cagattcatc cccagcccac tggcattggt taccggttga tacaaaccgg
    51361 cattgtcttc gatctccagc attaaatgtt gcccctcacg tcgggcgctg attgccactc
    51421 gccctgtatc cagcagttgt gatgtcccat gtttaatggc gttttccact atcggttgca
    51481 gggtaaacgc gggcaattgc tgctgggata attcttgcgg aatagcaatg ttgacctgca
    51541 accgcgactg gaagcgcgcc ttttcaattt gcagataagc attcacatgt tcaatttcgt
    51601 cggcgagagt aacaaactcc gaaggccgct ttaagttttt gcggaaaaaa gtggaaagat
    51661 actgcaccag ctggctggcc tgttcgctgt cgcgacggat caccgcttta atggtgttaa
    51721 gcgcattaaa caaaaaatgg ggattcacct gggcgtgaag cagtttgatc tctgactggg
    51781 tgagcatcgc tttttgccgc tcatattgcc cggcaaggat ctgcgccgaa agcagttgcg
    51841 caatcccctc acccaacgtg cggttgattg aactgaataa acggtttttg gcttcataca
    51901 atttgatggt gcccatcacc cgctgatttt caccacgcaa cggaattacc agcgtcgacc
    51961 ccagtttgca ttgcggatgc aaagagcaac ggtaaggtac ttcgttgcca tcagcgtaga
    52021 ccacttcacc ggtttcaatc gcttttaagg tataagtcga agaaatcggt ttgccgggta
    52081 aatggtggtc gtcaccaatt ccggtaaagg ctagcaattt ctctcgatcg gtaatcgcga
    52141 ctgcaccaat atccagctcc tgatacagca cctgtgccac tttcatgctg ttcacttcgt
    52201 taaacccctg gcgcaaaatg ccttccgtcg aggccgccac tttcagcgca gtggcagaaa
    52261 aagctgaagt gtatttttca aacatcgcgc gtttatcgag caatatacgc ataaacagcg
    52321 ccgcgccgac ggtattggtg accatcattg gcgcagcaat attactcacc agacgtaccg
    52381 catcttcata aggtcgggcg atcgccagga tgatcaacat ttgcaccatt tcagcgacga
    52441 acgtgacggc accggcggta atggggttaa agactttatc agtgcgcccg cgacggatca
    52501 gaatgctgtg taccaggccg ccgagcaatc cttcaacgat ggttgagatc atgcaactta
    52561 gcgcggtcat gccccccatc gaatatcgat gtaagccgcc ggtcagacca accagcccac
    52621 cgacgaccgg accgccgagt aagccgccca ttaccgcgcc tatcgcacgg gtattggcaa
    52681 tagaatcgtc aatgtgcaac ccaaaccagg tgcccatgat gcagaagatg gaaaagacga
    52741 tgtagcagag aaatttatgc ggcagacgaa ccgtgacctg cattaacggt atgaataatg
    52801 gcgttttact cattaaccac gcaatgacta aaaaaacgca catctgctga agcagcagca
    52861 acaccagatt aaaatcgtac atacccgcaa accacacttc cctttaaaac gcgtaacata
    52921 cattgcctgc gtttaacttt ctttgaactc ttgcagaaaa atgagaattc gtgagtacga
    52981 tcactcaaaa tcgcctggca aaaataaaat caccctatag atgcacaaaa aacgggcaaa
    53041 actacctggt tcgcaaaact gcgtctaaag ttaaaccggg acctcgcgag caagggtgag
    53101 acgatggcgc tttacacaat tggtgaagtg gcgttgcttt gtgatattaa tcctgtcacg
    53161 ttacgcgcgt ggcagaggcg ttacggattg ctgaaaccgc aacggacaga cggcggtcat
    53221 cggctgttca acgatgccga tattgaccgg atccgcgaga tcaaacgctg gatcgacaac
    53281 ggcgtgcagg tcagcaaagt taaaatgctg ctcagtaatg aaaatgttga tgtgcagaac
    53341 ggctggcgcg atcagcaaga aacattactg acttacctgc aaagcggcaa tctacatagc
    53401 ctgcgaacgt ggatcaaaga gcgcggtcag gattaccccg cccagacact caccacacat
    53461 ctgtttattc ctctgcgccg acggcttcag tgccaacaac cgactctcca ggcgctgctg
    53521 gcgatcctcg acggcgtact gatcaactac atcgccattt gtctggcttc ggcacgtaaa
    53581 aaacagggta aagatgcgct ggtggttggc tggaatattc aggataccac ccgtctgtgg
    53641 ctggagggct ggagggctgg attgccagtc aacaaggatg gcgcattgat gtcctcgccc
    53701 actcgctcaa tcaactacgc cctgaactat tcgaaggccg tacattgctg gtgtggtgcg
    53761 gtgaaaatcg aacctccgcc caacagcagc aactcaccag ttggcaagaa caaggccatg
    53821 atattttccc actcggcatt taatgattcg ttaacaaatg cgctttactg tacaatcctt
    53881 tcgttaacat aaggagtgca ttatgcgcat agctaaaatt ggggtcatcg ccctgttcct
    53941 gtttatggcg ttaggcggaa ttggtggcgt catgctcgca ggttatacct ttattttgcg
    54001 tgctggctaa gcgcctgcac cagcctttca aacaggcggt ctgcgatgat cgccgccagt
    54061 gccaccagta acgccccctg gatcacatac gcggtattaa atccgctaag cccgatgatg
    54121 atgggcgtac ccagcgtgct ggcccctacc gttgaggcga tcgtcgccgt accaatgttg
    54181 ataatcaccg aagttcgcac gcccgccaga atcaccggag ccgccagcgg tagctcgacc
    54241 ttacgcagtc gctgaccacg actcattccc atacctttcg caacttctgt cacgctggca
    54301 tcaatcgctc ccagcccggc aagtgtcgcc tgcaggacgg gcagcacacc gtaaaggatc
    54361 aaggcgataa tcgctggttg cagaccaaag ccgatcaccg gaacggcgat cgccagcact
    54421 gcgacgggcg gaaaagtctg tccaacggcg gcaatagttt ccaccagtgg gcgaaattcc
    54481 gcgccccacg ggcgagtgac agcaattccg gcaccagtgc caatgatcac cgcaaacaaa
    54541 ctcgaaattc ccaccagcca gaaatgagcc agtgccagag ctgcaaaact ttcttgctga
    54601 taaacgggtc gtggcagttg tgggaacaag gcagcaaaca gcggctggct gtaaggcagc
    54661 cagaaaatca gcgccacaaa cagagcaatg agccagaaca gcggatcgcg caacatcttc
    54721 atacgcttac gcctccacca gcagatcctg aaaatgcagc gtgccgcaag gctggccctg
    54781 catgttcacc accggcagca cctcgcatcc ccgcgcaaca aacagagaga gcgcatcgcg
    54841 tagcgtcatc tcttctgcca gtgcctcacc atctgctcgt tcttcgcgac gcacgtaatc
    54901 cgccacacta cgtaacgaaa gcaggcgcac acccagttca ctacgtccaa aaaactggcg
    54961 gacaaaatca ttcgccggac gagtcagcat cgtcagcgga ttgccctgct gcactacttc
    55021 accgtgatcc atcaatacca gatgttctgc cagccgtagc gcctcatcaa tatcatgagt
    55081 gaccagcaca atggtacgcc ccagcaaacg gtgaatgcgc gtcatctctt gttgcaacgc
    55141 gccgcgcgtt accgggtcca gtgcgccaaa aggttcatcc attagtaaga cttgcggatc
    55201 ggcagccagt gcacgcgcca ctcccacacg ttgctgctga ccaccggaaa gctgatgcgg
    55261 ataacgctca cgcaaatttg actccagccc cagtagcgcc attaattcgt cgatacgatc
    55321 gtcaatccgc gcccgcgacc atttttgtaa ttgcggcacg gtagcgatgt tttgcgccac
    55381 gctccagtgg gggaacaggc caatagattg aatggcatag cccatccggc ggcgcaactc
    55441 cagtactggc agcgagcgaa tttcttctcc ggcaaagcgg atcactccgc tgtcatgctc
    55501 caccaggcgg ttaatcattt tcagggtggt ggatttgccg gagccagatg tgccaatcag
    55561 caccgaaaaa ctcccttcct gaaaattgag attgagatcg ttaacggctt tttgtgcgcc
    55621 gaacagtttg ctgacatggc taaattcaat cattacgttt caccttcagc agtgcgataa
    55681 gcaaatcgaa cagcgcgtcg gtaagcaccg ccagaacaat taccgggatc acccccagca
    55741 acactaaatc aatggcgctg cttagcagcc cctggaaaac cagcgcacca aaaccgcctg
    55801 cgccgattaa cgccgcaatc accgccatac ctacagtttg caccatcacc acccgcaggc
    55861 tgcgcagaaa taccggtaac gccagtggta actgaacatg caggaatcgc cgcgccccgc
    55921 tcatgcccat cgctctggcg ctctccagca catcgcgcgg gatctggttc aagccgacta
    55981 ccacgccgcg caccagcggc agcaaggcat agagcaccag cgcaatcagt gcgggtgtca
    56041 ttccggttcc tgctatgccg agcttcccca gccacggaaa ggccgtcacc agcgcggcaa
    56101 gcggcgcaat caacaggcca aagagcgcca ccgaaggcac ggtctgaatg acattgagca
    56161 gagaaaaaat tgccccctgc cgagcagtgg aaaagtagca ccagatgccc aacggcacac
    56221 caatcactaa cgcaggcagc accgcaccaa acagcaacgt cagatgttgt gccagcgcgt
    56281 cgtcaaacac atcctgacgg ttggcgtatt ctttcattag tgagagatcg ttaagcgtgc
    56341 cggagtacag caaccacagc ggaataatgg caatctgcat atgcaacaac cagcgccaca
    56401 gcgaatgcgt ggagattcgg cggatggcat cgctacaggc cagcaatgcc agcgccgcag
    56461 ccagccagaa accactgccg aggctggtac gcgccagcgc actgccattt tgcgccagtt
    56521 gggtcgccgc ctttccagct ccccacacca gcaatacgaa gacgaattgc gccagaatga
    56581 gtgcacaaat gctgcctttt ttaccgggaa taaaacaggc cgtcagccag gcgcaaccaa
    56641 cgcccaccag catccagatc gtttgcggcc acagctgcca gagatgacgc ccctcacccg
    56701 aaactaaacg attaggcgcg taactgataa acggcagcgc cgctgcgatt gccgtcagca
    56761 acagcagcag cgccagaaca ggattaatac ggaaataagt cacgggaaat tacttcgtcc
    56821 accctttttg tttcaggtag tcggcagcca cttttttggc atccagtcct tccacagcaa
    56881 tgctggcatt cagttgctgc aatgtttttg catcgaggct ggcgaagact ggctgtagcc
    56941 actgtgccat ttgcggatac tccctcaaca ccgactcacg caccactggt gcaggcgcgt
    57001 agataggttg cacacctttc ggatcgctta aggtttgcag ccccagcgcc gctaccgggc
    57061 cgtcagtgcc gtaagccatt gcagcattaa cgccagaggt ttgctgggca gcggctttga
    57121 tcgtcaccgc cgtgtcgcca ccagccagtg acagcaactg atcctgaccg agcttaaagc
    57181 cataggcttt ttcaaacgcg ggtaacgcat cggcgcgttc gataaactct gccgaggctg
    57241 ccagtttgaa ggtgccgccc tcttgcagat aacgactcag gtcggcaagc gaagtgagtt
    57301 tatttttctc tgccacatcc tgacgcacgg cgatagtcca ggtgttattt gcaggcgcgg
    57361 gcgtcagcca gattaacttg ttgtgctccg aatcgagctt tttgactttc tcgtaacctt
    57421 gctgcgcgtt tttccacgct gcatcgtttt catctttaaa gaagaaagcg ccattgccgg
    57481 tatattccgg atagatatcc agttcatcgg aagtaatcgc cccgcgcacc acaggagtcg
    57541 ttccgagttg cactttattc accgtcggta cgccgtggct ttccagcacc tgcaaaatga
    57601 tattgccgag tagcgcacct tcggtatcga tttttgaacc gactttaacg ggggaagccg
    57661 cctgtagcgg caggctcacg gctgccaaca taaccagtga acctgcccag agctttaaga
    57721 gtggcatgat gctttcctca ttcttttact gttgttttca gcgaattaag agaaaagcat
    57781 agttgataat ggcggggtta gcttgagcgg aaggattcag ttgcagaatc agataaatac
    57841 ttaagaggca tattcggtcc ggcgtttcct gccggatgcg gcgcgagcgc cttatccggc
    57901 ctacaaaggg cgaaaattca gcaagttaag atatgaacat caggcaaagg gcgcaaacgt
    57961 cgcgccctta caaaagcatt acagcaactc aaactcgcct ttcttaacgc gtgcggaatc
    58021 agtgccgata aagacattga acttgccagg ctcggcgtca tatttcatct gttgattcca
    58081 gaacttcagc gcctcaatat caatcgggaa gctgacggtc tgagtttcgc ccggcttcag
    58141 ggtgattttc tcaaagcctt tcagctgttt cacagggcga ctcatggaag ccgtcacatc
    58201 ctgcaagtac atctgcacta ccgtggcacc ctcgcgctta ccggtgttcg tcacctgcac
    58261 gctggccgtc actttgccgt cacgcttcat ggtcggcgca gaaagtttca catcagagac
    58321 ggtgaaagtg gtatagctca gaccatagcc gaacggataa agcgccccgt tagcttcatc
    58381 aaaataacgc gaagtgtatt tgttcggctt gtcggcatta tacggacgac cggtgttcag
    58441 atggctgtag tacaccggga tctgcccgac agaacgcggg aaggacatcg gcagcttgcc
    58501 ggacgggttg taatcgccaa acaacacatc ggcaattgca ttaccgcctt cagtccccgc
    58561 aaaccaggtt tccagaatcg catcagcctg ctgatcttct ttcaccagcg ccagcggacg
    58621 cccgttcata agcaccagca ccagcggttt accggtggct ttcagcgccg caatcaagtc
    58681 acgttggctt tgcggaatag tgatatcggt ccggctggag gcttcgtgcg ccatcccctg
    58741 tgcttcaccg actacagcca ccaccacatc agattgtttc gccgtctgca ccgcttcatc
    58801 aatcatctct tgcggcgaac gcggatcgac tttgaccgct tcttcatact gattcaggaa
    58861 atcgataatg cctttgtcac tggtaacgtt cgcccctttg gcatacagca ctttaccgtt
    58921 ttcaccgacg gcatttttaa tcccggtcag tacggtcacg gattgatcgg caacaccggc
    58981 tgcggaccag ctgcccatca cgtcacgttt actgtccgcc agtggcccaa ccaccgcaat
    59041 ggtggccgat tttttcagcg gtaacgtttc gagacggttt ttcagcaaca ccaagctttc
    59101 gcgcgctact tcacgcgctt ctttacggtg caggcggctt tcggcattgg tatccaccgg
    59161 gtcagactct ttcggcccca aatggctgta tgggtcgtta aacaacccca tatcatattt
    59221 aacgttcagt acatggcggg cagcatcgtc cagctctgcc atcgtcactt tgccggattt
    59281 aatcaaccca ggcagatact tcgagtagta ctcgtcactc atgctcatgt tgattccgga
    59341 tttcagcgcc acgcgcaccg catcttccgg gtctgccgcc gtgccatgtt taatcagctc
    59401 tttgattgca ccgtgatcgg aaacggtgat gcctttaaag ccccactggt cgcgcagaac
    59461 atctttcagc agccaggaat cggaggtggc tggcgtgccg ttcagcgagt tcagcgccac
    59521 catcaccgcg ccgctgcctg cgtccagccc cgctttgtac ggcggcatat aatcattaaa
    59581 caggcgctgc ggactcatat cgacggtgtt gtactcttta ccgccttcta ccgcgccgta
    59641 tgcggcaaag tgtttgacgc tggtcatcac cgagtagcga tctgccgggc ttttaccctg
    59701 catcgcttcc accatggttt tacccattgt tgaggtgaga tacgtatctt cgccaaaacc
    59761 ttcggaagca cgtccccagc gcggatcgcg cgagacatcg accatcggtg cccaggtcat
    59821 attcaggcca tcatctgccg cttcataagc agagacacgt ccgaccgttt tcactgcatc
    59881 gaggttaaaa gacgaggcca gaccgaggct aatcgggaac accgtgcgct gaccgtgcag
    59941 cacgtcgtaa gcaaagaaaa gaggaatttt caggcggctt aattccatca cctgatcctg
    60001 catggcgcgg atatcctgac gggttacggt gttgaaaatc gccccaacct gaccgtcttt
    60061 gatcatctcg cggatcgcct ctttcgggtt atccgggccg acgctgatta agcgcagctg
    60121 accaattttc tcatcaactg tcattttctt aagcagttcg gtgacgaacg catcccgcgc
    60181 ttcgggcgtt aatggatggt tgccgaataa atcatccgcc agtgctggct gcagggccag
    60241 actcaccgcg attcctactg aacatagcca tttcatatgg atttttcttc ctctgttgcc
    60301 cgacgaggca gcgaaaatgg tgcaaaaacc gtagtttgcc ataagcatga tggagagaga
    60361 aaaagaatgc tcagtttatt gtctgaattt tcaaaatatt cactcgctga attgtcatac
    60421 aaggcgctat tctagtttgt gatatttttt cgccaccaca aggagtggaa aatgtcttcc
    60481 atgacaacaa ctgataataa agcctttttg aatgaacttg cccgtctggt cggtcattca
    60541 cacctgctca ccgatcccgc aaaaacggcc cgctatcgca agggcttccg ttctggtcag
    60601 ggcgacgcgc tggctgtcgt tttccctggc tcactactgg aattgtggcg ggtgctgaaa
    60661 gcctgcgtca ccgccgacaa aattattctg atgcaggctg ccaatacagg cctgaccgaa
    60721 ggatcgacgc caaacggtaa cggctatgat cgcgatatcg tgatcatcag caccctgcgt
    60781 ctcgacaagc tgcacgttct tggcaagggc gaacaggtgc tggcctatcc gggcaccacg
    60841 ctctattcgc tggaaaaagc cctcaaaccg ctgggacgcg aaccgcactc agtgattgga
    60901 tcatcgtgta taggcgcatc ggtcatcggc ggtatttgta acaactccgg cggctcgctg
    60961 gtgcaacgtg gcccggcgta taccgaaatg tcgttattcg cgcgtataaa tgaagacggc
    61021 aaactgacgc tggtgaacca tctggggatt gatctgggcg aaacgccgga gcagatcctt
    61081 agcaagctgg atgatgatcg catcaaagat gacgatgtgc gtcacgatgg tcgtcacgcc
    61141 cacgattatg actatgtcca ccgcgttcgt gatattgaag ccgacacgcc cgcacgttat
    61201 aacgccgatc ctgatcggtt atttgaatct tctggttgcg ccgggaagct ggcggtcttt
    61261 gcagtacgtc ttgatacctt cgaagcggaa aaaaatcagc aggtgtttta tatcggcacc
    61321 aaccagccgg aagtgctgac cgaaatccgc cgtcatattc tggctaactt cgaaaatctg
    61381 ccggttgccg gggaatatat gcaccgggat atctacgata ttgcggaaaa atacggcaaa
    61441 gacaccttcc tgatgattga taagttaggc accgacaaga tgccgttctt ctttaatctc
    61501 aagggacgca ccgatgcgat gctggagaaa gtgaaattct tccgtccgca ttttactgac
    61561 cgtgcgatgc aaaaattcgg tcacctgttc cccagccatt taccgccgcg catgaaaaac
    61621 tggcgcgata aatacgagca tcatctgctg ttaaaaatgg cgggcgatgg cgtgggcgaa
    61681 gccaaatcgt ggctggtgga ttatttcaaa caggccgaag gcgatttctt tgtctgtacg
    61741 ccggaggaag gcagcaaagc gtttttacac cgtttcgccg ctgcgggcgc agcaattcgt
    61801 tatcaggcgg tgcattccga tgaagtcgaa gacattctgg cgttggatat cgctctgcgg
    61861 cgtaacgaca ccgagtggta tgagcattta ccgccggaga tcgacagcca gctggtgcac
    61921 aagctctatt acggccattt tatgtgctat gtcttccatc aggattacat agtgaaaaaa
    61981 ggcgtggatg tgcatgcgtt aaaagaacag atgctggaac tgctacagca gcgcggcgcg
    62041 cagtaccctg ccgagcataa cgtcggtcat ttgtataaag caccggagac gttgcagaag
    62101 ttctatcgcg agaacgatcc gaccaacagc atgaatccgg ggatcggtaa aaccagtaaa
    62161 cggaaaaact ggcaggaagt ggagtaaaaa ttacggatgg cagagtatcg ccatccgaat
    62221 tcacttaatc gttctgtgcc gtctgccccg ccgccgccat ttgggcggct ttttgttttt
    62281 tatagctcaa cgctgctgcc ggcacaggca tcactttacc ggtttcaatc caggtacgca
    62341 ggcggctggc atcggcaaaa tgggtatatt tgccaaacgc gtccatcact accagcgcca
    62401 ccggtttatt attgataacc gtacgcatca ccagacaatg gcccgccgca ttggtaaagc
    62461 cggttttggt taactgaata ttccagttat cgcgatacac cagatgatta gtattgcgga
    62521 acggcagcgt atacgtcgga ttagagaagg ttgccatatc ttcccgggta gtacttaact
    62581 gcccgatcaa cggatattgt ttgctggcaa tgagcagttt ggttaagtca cgggcagttg
    62641 aaacgttatg caccgacaat ccggtaggtt caacaaagcg cgtgttgttc attccgagcg
    62701 atttcgcttt cgcattcatt gccttaataa aggctttgta accaccggga taatggtgcg
    62761 caaggcttgc cgccgcgcgg ttttctgaag acatcagcgc cagcaacagc atatctttac
    62821 ggctgatttc gctattcagt cgtacgcgcg aatagacccc tttcatctcc ggcgtctggc
    62881 tgatatccac ttttagtttt tcatccagcg gcagtcgtgc atccagcaca accatcgcgg
    62941 tcattaattt gctgatagac gcaatcggac gcaccagatc cgggtggttc gaatagatca
    63001 ctttgttggt attcagatca acaatcatcg cgctaccgga ggcaatttcc ggttgtgaag
    63061 cggtggtagc ggctgccgtt ttcgcaacgg cctgcggtgc caaaggcaca gccagcatca
    63121 gggccaggct aaataaagaa actcgaaatt tcggcatgat gagcattcag atagtggttc
    63181 acgcgcacgg gttgcgcacc gccggagtaa ggatttactg aggctagcga cgccatcata
    63241 acgagcaaaa agtgcgatcg tcaaaggaga atcgtgagga aatgctgcat tgctgacatt
    63301 tacgccagca atgcaacgtc aaagaacttt ctagaacaaa cgataaccgt agccccatag
    63361 tataacggtt agggcgagca gcacttccag taccagcacg ccaatcgcca gcgtcgaact
    63421 agagaagcta aggccttcct ctttgttgat attcaggaag ctcggaatac caaggtaaag
    63481 caggtagccg gtgtaaaaca gcgccaccgt gccgaccagc gcacacaacc agaccagtgg
    63541 ataaagcgcc accagaccgc ttaaaaacag cggagttgca acgtagcccg cgaagaccat
    63601 gcagtgcgca agtgacggac gctgcggata attacgcgcc atccaccaga tgacccgccc
    63661 cattaccgca accccagcca gcataacgcc ataaaacagg acagccagcg ccagtccggt
    63721 aaaccaggat aacttcagga tagtgccatc gccaaaattc cagccaatct gtgtagtgcc
    63781 aatgaaggcg caaatcaccg gaatcgccgc catcagcaaa acgtggtggg tgtaatggtg
    63841 agaaatcgtt tcgttttcgc gattaatcac ctgcatttca cgatcgggat gggaaaacag
    63901 tccccagaca tggctcatac cgcccccttg ttgtgagttc atgaacctga cagttcaagt
    63961 ataagtcagc ttgtgattat tttttgttcg ctcatgtaat ttgcaccgtc tgatgtacgt
    64021 cctttttcag cgtgaatgat ttccagggtg tatgcttaaa ggcaaccaaa gggagacaga
    64081 ctggcctatg gatctcaata cactcatctc acaatatggt tatgccgcgc tggtgatcgg
    64141 tagcctggcg gaaggtgaaa ccgtgacttt gctgggaggc gttgcggcac atcaggggct
    64201 attaaagttc ccgctggtgg tactttctgt ggcgcttggc ggcatgattg gcgaccaggt
    64261 gctttatctg tgcgggcggc ggtttggcgg caagctgtta cgccgtttct cgaaacatca
    64321 ggataaaatt gagcgggcgc agaaacttat ccaacgccat ccgtatctgt ttgtcattgg
    64381 tacgcgcttt atgtatggct ttcgggtgat tggcccgacg ctgattggtg ccagccagct
    64441 gccgccgaaa atctttctgc cgcttaatat tctcggcgca tttgcctggg cgttgatttt
    64501 taccactatc ggttacgctg gtggtcaggt gattgcgccg tggttgcaca ctctcgacca
    64561 gcatttgaag cactgggtct ggttgattct ggtcgtggtt ctggtggtag gcgtgcgctg
    64621 gtggctgaaa cggcgcggga agaaaaagcc ggatcatcag gcgtaaaacc attgccctgg
    64681 gtaaggcgtt cgcgccgcat ccgacatccg gtgcaccatg cctgatgcga cgcttgtgcg
    64741 tcttatcatg cctaccaaaa ttttacccat tgaaataacc acgcacctca ctgcgctatt
    64801 ctgggttgaa ctgcggattc gccaacataa agccgccatc cactatcaac gactgcccgg
    64861 tggtgtaatt tgcgccctct gagcacagcc acgctaccag gctggcaatc tcatgcgttg
    64921 cgccaaaacg ccgcagagga atcgaaggct ccgcgtcggg cttcacgtcg ctgtcatcca
    64981 tgccattcat tggcgtggcg atcgccccag gcgcgactgc gttcaccaaa atcttatgcc
    65041 tgaccagctc cagcgccatc gctttggtta acccaccgag cgcatgttta gcggctgtgt
    65101 aggcgctggc atccggcagc ggcgtatgtt catgtaccga cgtaatgttg atgacgcgac
    65161 cgccctgccc ttgtttcacc atctggcggg ccgcaatttg tgagcataaa aatgcaccat
    65221 cgacatcaac ggtaaaaatc ttgcgccact catcgaaagc catatcaaga aacggcgctt
    65281 tggtcattgc gcccgcatta ttcaccagca catcaatacg ccccagccgt tgaatgagtt
    65341 tctccagcgc ctgcgcacct tctggcagtt taccgagatc cagctgcacg atctccgcac
    65401 gtacgccgtg gctaactacc tcacgcgcgg tatcttttcc cccttcttca tctgagttcc
    65461 aggtaatacc aatatcaaac ccctgctgcg ccagtaataa cgcgcactct ttgccgatcc
    65521 ccgaatcgga ggcggtaata atcgcaacct gtgccatcga gttctccact taacgctgaa
    65581 taaacgttaa gtatagaagg cgcatatcat cagcgtttgt aacccccgcc caacgcacca
    65641 gtgagttgaa tggaggcatc cagccactgc ccttgcaata acaggccatt ggcccgctca
    65701 cgcagcgcgg ggattctggc ttcgctgacg cgggaaccag caatgatgcc cgcgttaaag
    65761 cgcgcctgcg caagacctac cacacgcaag gcatcgcgct caatttgcgc ctgatgctgg
    65821 tttttctccg ccagtgtctg aacctgactg gctgcccgcg ccacgtcatt caccgcttca
    65881 accaccgctt tgttgtagct ggcgatagac aagttgcttt cggcttttgc gatatcgaga
    65941 ttggcgttaa gacgaccact atcgaaaatg ggtagcgtca ggcctgccgt aacgcccatt
    66001 tgctgcgcgg aatgacggaa cagatcgctt aagtgcaacg catcctgttg caggaaggcc
    66061 atcaggttga tgtcaggata aaatgccgct tttgccgcat caatggtgct tagcgatgac
    66121 tcaacgtacc agtgcgccgc ctgcaaatct gcccgccggg ccagtaagga gtaccccagt
    66181 tcatcaggaa gctggcttgc cactttcggc aacgcgaccg gtttaagctt caatgacttt
    66241 gtctggttat ttgtaagtgc gcttaaccgt gcctcaataa ttttcatttt ccccgcgaca
    66301 tcgttgagct gctgccgggt tttgctggca ttaatatcgg tttccacacc ttcaactgaa
    66361 gaagtaatcc cgttctgata tagctggcga tcggtcgcga taatggtgtt ctgctctttt
    66421 tctatttgct gcaagaccgt gtttaacgcc gcctgggttt gccactccca gtacaggcgg
    66481 gctacgctgc cagccagcaa ttggcgggtt tgctcgcgtt ccgccgcccg tgctttaacc
    66541 gtacccaggc gggcagtaac ctccgcccga ttctttcccc agatatcgag ctgccagccc
    66601 gccgttaagc caaaagtacc gttggtgtac cacgggccgg tcgtacctgc ggccggatcg
    66661 ttcagagcaa acggccccat taagccttct gccgacattt tttgccgctc catatccgcc
    66721 gaaaagtcga tctgcggacc atcctgagtg gcaactgcct tcgcctgggc ttcagctagc
    66781 tgaatgcgct gttcagccac ctgcatatcc ggtgcgttct gtagtgcatt gttaattaag
    66841 gaagtgagtt gattatcgtg atactccagc caccattggc tgtctggcca accatttttc
    66901 agcgccgtgg gtaatgcggt gtcaacttgt gcagcgggcg tttgctggct taacgcctgg
    66961 cgggtttcat gcataggcgc acacccggcc agcatcagta acagcggaaa acaggcgatg
    67021 gctggataaa aggaatcacg attcatgggg gaataatcag gtaagaaaag gtgcgcgaag
    67081 attaccgtgt gttgcgatat attttttagt ttcgcgtggc aatacatcag tggcaataaa
    67141 acgacatatc cagaaaaata tacactaagt gaatgatatc ttccgattta tcttaatcgt
    67201 ttatggataa cggcaaaggg cttcgttttt tcctatactt attcagcact cacaaataaa
    67261 ggaacgccaa tgaaaattat actctgggct gtattgatta ttttcctgat tgggctactg
    67321 gtggtgactg gcgtatttaa gatgatattt taaaattaat taatgtcatc aggtccgaaa
    67381 ataacgagaa tatttcagtc tctcatcctg ttgcgctcct gtcatgtgca ttgcttcata
    67441 taatcactgg cgcaaggagc gcgcaggggg cggccaatcg ccgccgcccc ctgcaccccc
    67501 gggctctggc gaacaaaatc gccgctgcgc ggtgccctcg gcttatccct tacggctacc
    67561 gggtcgggcg cgaggtaaca tccctgtaaa acgcgccctc agcccacatc catgtgggct
    67621 gccccggcct tcagggaacg cctcggcaat tttgacgcca ccaaacaacc gtgcggccta
    67681 ttgataaaga gctaacacat tgtcaaaaaa catcactatg gttttttaga gtttctcgat
    67741 atcaattgcc tgaatagccc ttgcaatatc aggggaatta ttcaacaccc gaacatgctg
    67801 aaataattcc gttgcttcat cgtattcttt acgcaaataa ctcaaccact gtttaatccg
    67861 cgcaacgtga tataacccgg tatcgccctg cttttccaga cgggtatatt tttgcagcaa
    67921 agcaaccacc tccggccacg gcattcgcgg ttcgttatat tttaccaccc ggctcaggtt
    67981 gggaatattg agcgccccgc gaccaatcat cactgcgtcg cagccgctga tcgccatgca
    68041 ttgttgcgcg ctctgccagt cccagatttc accgttggca atcaccggaa tattcagccg
    68101 ctggcgaata tcgccaatcg cctgccagtc aatatgctcc gcgcggtaac cctgctcttt
    68161 cgtccgccca tgcaccacca gctccgtagc gccagcctgt tgaaccgcat cggcgatttc
    68221 aaatttcttc tcaccgctgt cccagcccag acgcactttc acgctgacgg gcaaatgcgc
    68281 cggtacagct tcacgcatcg cttttgcacc ctggtagatg agttcaggat ctttgagtaa
    68341 cgtcgccccg ccgccgctac cgttaaccgt tttcgacggg cagccgcaat tgagatccac
    68401 gccccaggaa cctaactcca ccgcacgggc ggcgttctct gccagccatt gtgggaactg
    68461 acctaacaac tgcacgcgca ccagcgtacc agatggtgtc cggctggcgt tttgtagctc
    68521 agggcaaatg cgatgaaaga cttttaccgg cagcagttga tccaccacgc ggacaaactc
    68581 ggtgatgcac agatcgtagt cgttaacttc ggtcagcaat tcacgcacca gagagtcaag
    68641 cactccctcc atcggtgcca gtaacacacg catatcatca cccgcaaaaa aatgaggcgc
    68701 tatgttagcg cctatggtca gcggattaaa ggtctgcaaa gagggattgc tgcaaactgc
    68761 aatccctctc tatgcttgat gtatgcctga gttcgctgcg cattgcgtaa tgccggggaa
    68821 cgaaaaaata agcgctgatt tcttaatgtg atcggtagca cgttttacga attaattgta
    68881 tgatgaatcc atctcatctg gggtgttgat tatgagtaag acactgaaca ttatctggca
    68941 atatttacgc gctttcgtcc tgatttatgc ctgcctgtat gcaggcattt tcattgcttc
    69001 cctgctaccg gtaaccattc cgggcagcat catcgggatg ctgatcctgt ttgtcctgct
    69061 ggccttgcaa attcttccgg caaaatgggt caatccgggg tgctacgtac tgattcgcta
    69121 tatggcgcta ttgtttgtgc cgattggcgt aggcgtcatg caatattttg atttgctccg
    69181 cgcacagttt ggcccggtag tggtttcctg tgcagtcagt acgctggtgg tttttctggt
    69241 ggtgagctgg agttcgcaac tggtacacgg tgaacgtaaa gtcgtaggtc agaaaggatc
    69301 agaagaatga tggcgaatat ctggtggtca ttaccgctga cattgattgt cttttttgcc
    69361 gcccgcaaac tggcggcacg gtataagttt cccttgctta acccgttgct ggtagcaatg
    69421 gtggtgatca ttcctttttt aatgctgact ggcatctctt acgacagcta ctttaaaggt
    69481 agcgaagtgc taaacgatct gctgcaaccg gcggtcgtcg cgctggccta tcctttatat
    69541 gagcagctac accagatccg cgcgcgctgg aaatcgatca tcaccatctg ttttatcggc
    69601 agcgtggttg cgatggtgac ggggacttcc gtggcattgt tgatgggcgc ttcaccggaa
    69661 atcgccgcgt caatcctgcc gaaatcagtc accacgccta ttgcaatggc ggttggcggc
    69721 agtattggcg gtattccggc aatcagcgca gtttgcgtga ttttcgtcgg catcctcggc
    69781 gcggtatttg gccatacatt gcttaatgcg atgcgtattc gtaccaaagc tgcgcgcggt
    69841 ctggcaatgg ggactgcctc gcacgccctc ggtacggcgc gctgcgccga gctggattat
    69901 caggaaggtg catttagttc gctagcgctg gtgttatgcg ggataattac ttcgctgatc
    69961 gcaccgttcc ttttcccgat tattctggca gtaatgggct aaaatttgcg atgcgtcgcg
    70021 catttttgat gtaagtttca cgcgttgcat aattaatgag attcagatca catataaagc
    70081 cataacgggt tcgtaaactg ttatcccatt acatgattat gaggcaacgc catgcatcca
    70141 cgttttcaaa ccgcttttgc ccaacttgcg gataacttgc aatctgcact ggaacctatt
    70201 ctggcagaca agtacttccc cgctttgttg accggggagc aagtctcatc gctgaagagc
    70261 gcaacggggc tggacgaaga cgcgctggca ttcgcactac ttccgctggc ggcggcctgt
    70321 gcgcgtacgc cattgtcgaa ttttaatgtt ggcgcaattg cgcgcggtgt gagcggaacc
    70381 tggtattttg gtgccaatat ggaatttatt ggtgcgacaa tgcagcaaac cgttcatgcc
    70441 gaacaaagcg cgatcagcca cgcctggttg agtggtgaaa aagcgcttgc agccatcacc
    70501 gttaactaca cgccttgtgg tcactgccgt cagtttatga atgaactgaa cagcggtctg
    70561 gatctgcgta ttcatctgcc gggccgcgag gcacacgcgc tgcgtgacta tctgccggat
    70621 gcctttgggc cgaaagatct ggagattaaa acgctgctga tggacgagca ggatcacggc
    70681 tatgcgctga ctggtgatgc gctttctcag gcggcgattg cggcggcaaa ccgttcgcac
    70741 atgccttaca gtaagtcgcc aagcggtgtt gcgctggaat gtaaagacgg tcgaattttc
    70801 agcggcagct acgctgaaaa cgccgcattc aacccgactc tgccaccgtt gcagggagcg
    70861 ttaattctat tgaatctcaa gggttatgat tacccggata tccagcgcgc ggttctggca
    70921 gaaaaagccg atgcgccgtt gattcagtgg gatgccacct ccgcaacgct gaaagctctc
    70981 ggctgtcaca gtatcgaccg cgtacttctc gcttaagcct ggtgccggat gcggcgtgaa
    71041 cgccttgtcc ggcttgccag ccctctcctg gtgtcgaaaa tcccggcaaa cagtttgccg
    71101 tttcttgcgc aaaaccagcg ggtaaagtag cctgatggaa attttcctta gatcgagtct
    71161 cctgcatgtt aaagcgcgtg ttcctcagcc tgttagtcct gatcggcttg ctgctgttga
    71221 ctgtgctcgg cctcgatcgc tggatgagct ggaaaaccgc gccttatatc tacgacgaat
    71281 tgcaggatct cccctaccgc caagtcggtg tggtgctcgg aacagcaaaa tattatcgta
    71341 ctggcgtaat taatcagtat tatcgctacc gcattcaagg agcgattaat gcctataaca
    71401 gcggtaaggt aaattatcta ttactgagcg gcgataacgc attgcaaagt tataatgagc
    71461 cgatgaccat gcgcaaagat ttaatcgctg ctggtgtcga cccatcagat attgttctcg
    71521 attacgcagg ctttcgtacg ctggattcca tcgtgcgtac acgcaaagtt ttcgatacta
    71581 atgatttcat tattatcacc caacgtttcc actgtgagcg agcattattt attgcgctgc
    71641 atatggggat tcaggctcag tgttatgccg taccgtcacc gaaagatatg ctgtcagtac
    71701 gtattcgtga atttgccgcc cgtttcggtg cgctggctga cctttatatt tttaaacgtg
    71761 aaccgcgttt tttagggccg ctggtcccta ttccggctat gcaccaggta ccggaagatg
    71821 cgcaggggta tcccgccgtc acacccgaac agttacttga attacaaaag aaacaaggaa
    71881 agtagttatg gatgtacagc agttttttgt cgttgccgtt tttttcctta tcccgatatt
    71941 ttgtttccgc gaagcatgga aaggctggcg cgcaggcgcg attgataaac gggttaaaaa
    72001 tgcaccggaa ccggtgtatg tctggcgagc aaaaaatccc ggactctttt tcgcttatat
    72061 ggtggcatat atcggcttcg gaattttatc tatcggcatg attgtttatc ttattttcta
    72121 tcgttaatat tcccctctcc agttaattat tgagaataat tattacttca cctgataagc
    72181 tgcggatatc acattcctaa ccgcagctat ttgtgaatct tttcacagtt taaattcccc
    72241 cgcacgctta gccttaatat cagtacatta ttatttacta aacgctcgcc ttaattacct
    72301 atagcattaa ggaagatcac atgccgcaac aaaattatct ggatgaactc actccggctt
    72361 ttacgtcttt actggcgatt aaagaagcct ctcgctgttt attatgtcac gacgctccct
    72421 gtagtcaggc ttgcccggca cagaccgatc cggggaaatt tattcgctca atctactttc
    72481 gtaattttaa aggcgctgcc gagacaattc gcgaaaataa tgccctcggt gccgtttgtg
    72541 ccagagtgtg cccaacggag aaattatgcc aaagcggttg tacccgtgcc ggtgttgatg
    72601 ctcccattga tatcggccgc ttacagcgtt ttgttactga ttttgaacaa caaaccggaa
    72661 tggaaattta tcagcccggt actaaaacgc tcggcaaagt cgcgattatt ggcgcaggtc
    72721 ctgccggatt gcaggccagt gtgacactga caaaccaggg ttatgacgtc acgatttatg
    72781 agaaagaagc gcaccccggt ggctggttgc gtaacggtat tccgcaattc cggttaccgc
    72841 aatcagtgct ggatgcagag atcgcccgta ttgaaaaaat gggcgtgacc attaagtgca
    72901 acaacgaagt cggtaacaca ctcaccctgg agcaactgaa agcggaaaac cgcgcggtac
    72961 tggtcaccgt ggggttatca agcggttccg ggctaccgct gtttgagcat agcgacgttg
    73021 agattgccgt cgacttcttg caacgtgcac gacaggcgca aggcgatatc agcattccac
    73081 aaagcgcatt aattatcggc ggcggtgatg tcgcgatgga cgtagccagc acgctgaaag
    73141 ttctcggctg tcaggcggta acttgcgtag cgcgtgaaga gttagatgag tttccggcaa
    73201 gcgaaaaaga gtttaccagc gcccgggagc tgggcgtttc gatcatcgat ggattcacgc
    73261 cagtagccgt ggaaggcaat aaagtcacgt ttaagcatgt acggttaccg ggcgaactga
    73321 cgatggtggc agataaaatt attctcgccg tcggtcagca tgccagactg gatgcctttg
    73381 cgaagttaga gccgcagcgt aacaccatca aaacacaaaa ttatcagacc cgcgatccgc
    73441 aagtctttgc tgctggcgat attgttgagg gtgacaaaac cgtggtctat gccgtgaaaa
    73501 ccgggaaaga agccgccgag gcgattcatc actatttaga gggagcttgc tcatgttaac
    73561 gaaagatctt tcgattacct tttgcggcgt gaagtttccc aacccgttct gcctctcttc
    73621 ttcgccggta ggcaactgct atgagatgtg tgccaaagcc tacgacacag gttggggcgg
    73681 cgtggtgttt aaaacgatcg gcttttttat cgccaacgaa gtctcgccgc gttttgatca
    73741 tctggtgaaa gaagataccg gttttatcgg cttcaaaaat atggagcaga ttgccgagca
    73801 tccgttggaa gagaatctgg ccgccctgcg tcggctgaag gaagattacc cggacaaagt
    73861 attgatcgct tcgatcatgg gggaaaatga gcagcaatgg gaggagctgg cgcgcctggt
    73921 gcaagaagct ggcgcggata tgatcgagtg taacttctcc tgtccgcaaa tgacgtctca
    73981 tgcgatgggt agcgatgtcg ggcaaagccc ggagctggta gaaaaatatt gtcgggcagt
    74041 taaacggggt tccacgctgc cgatgctggc gaagatgaca ccgaatatcg gtgatatgtg
    74101 cgaagtggcg ctggcggcga agcgcggcgg cgcagatggc attgcggcaa ttaacaccgt
    74161 taaatccatc accaatatcg atcttaatca gaaaatcggt atgccgatcg tgaacggtaa
    74221 atcgagtatt tccggatatt ccggtaaagc ggtaaaaccg atcgccctgc gctttattca
    74281 gcaaatgcgc acccatccag aactgcgcga tttcccgatc agcggtatcg gcggcattga
    74341 aacctgggaa gatgcggcgg agtttttatt gctcggcgca gcaacgttac aggtcaccac
    74401 cggcattatg cagtacggct atcggatagt ggaagatatg gcgagcgggt tgtcgcatta
    74461 tctcgccgat caagggtttg attcgttgca ggagatggta ggtctggcga ataacaatat
    74521 tgtcccggcg gaagatttag accgcagtta tattgtctat ccccgtatca atcttgataa
    74581 atgtgttggc tgtggacgct gttatatttc ctgttacgac ggcggtcacc aggcgatgga
    74641 atggagcgag aaaacccgca caccgcattg taataccgag aaatgtgtgg gttgtctgct
    74701 ttgtggtcac gtctgcccgg tgggttgtat tgagctcggg gaagtgaagt ttaagaaagg
    74761 cgagaaagaa cacccggtaa cgttgtaaaa ccagagacgc atccggcatt tggcaccgat
    74821 tgccggatgc agcgcatccg gcaatatcca caatcacatc acttcttacg cgcgtatttc
    74881 agtgaatcca gcgctacggc gaagataata atcgcccctt tgatgatgta ctgccagtat
    74941 gggtttacgc cgatatacgt caggccatag ttgatgacgg taaaaataat taccccggtc
    75001 accacgccaa tcaccgtccc cacaccgccg ctgaacgata caccgcctac cacgcacgcc
    75061 gcgatagcat ccagctcata cataaagccg aggttgttgg tggcagagcc gatacgtccg
    75121 gcttctaaca tcccgccgaa ggcatagaac acaccagaca acgcgtagat catcagcagg
    75181 ttcaggccga cgttgacacc agatactttt gccgcttccg ggttaccgcc aatggcaaaa
    75241 atgttcttac cgaagcgggt tttgttccac aacacccaga cgaacgccac cgcaatcaac
    75301 gcgtagaagg tgatgtaaga gagacggaaa ctccccagca cgacaaagcc ctgagcaaag
    75361 gtagagaagc cactgtcaaa accagaaatt ggcgacgccc cgacaaagtc gtaatagagc
    75421 gagttgatgc catagacgat gatcatcgtg ccgagcgtgg taatgaacgg cgtcacgttg
    75481 agataagcga taatcagacc gttgatcaaa ccgatcaccg caccaatggc acagacaatc
    75541 agaataacca gcgcaatcgg catcgtcgcc atttccggga acactttgtt ggcgttatcc
    75601 atggactgca ataatgtcgc agccaccact gccgccagcc ctacctgacg accagcagaa
    75661 agatcggtcc cctgggtgac aattaaccct gccacaccga gcgcgataat aatacgcacc
    75721 gatgactggg tgagaatatt acttaagttc aacagactta aaaatgttgg gtcctggaaa
    75781 ataataatcg ccagcaaaac taaaagaacg acgtaaatac cgccctcttt caggtaagta
    75841 agaaaacttt tcttatttaa cgcactcatg ggaagcccct aatcttaaag gtgcaaagac
    75901 gcaagacgca gaatttcgtt ttgcgttgtt gtttttgtgt cgacaattcc ggaaacgaga
    75961 ccattgctca tgaccagaat acggtctgtt atccctaaca actcaggcat ttcagaggag
    76021 ataataataa tccccttgcc tttcttcgcc agttcggcaa ttaactgata aatttcaaac
    76081 ttcgccccga catcaatacc gcgcgtcggt tcatcgagca ttaatatttc tggttgcgtt
    76141 agtagccagc gaccaataat caccttttgc tgattaccac cggagagcga accaatttgc
    76201 gtcc
//
LOCUS       DACAOP010000009        75576 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.009, whole genome shotgun sequence.
ACCESSION   DACAOP010000009 DACAOP010000000
VERSION     DACAOP010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 75576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75576
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.009"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..701
                     /locus_tag="IT892_000677"
     CDS             <1..701
                     /locus_tag="IT892_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP3133919.1"
                     /translation="LEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRP
                     NLLLLDEPTNHLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYLVHDRKVEP
                     FDGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIA
                     RLEKEMEKLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEA
                     QEQLEQMLLEGQSN"
     gene            701..1723
                     /locus_tag="IT892_000678"
     CDS             701..1723
                     /locus_tag="IT892_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP3133920.1"
                     /translation="MAQITTTDANEFSSSAEFIPMRGFSNCHLQTMLPRLFRRQVKFT
                     PYWQRLELPDGDFVDLAWSENPAQAQHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGW
                     LGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
                     CLLAKEGNDLPVDAAVIVSAPFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAY
                     PGTLPINLAQLKSVRRIREFDDLITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIH
                     AKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTY
                     LEAKSC"
     gene            1717..1935
                     /locus_tag="IT892_000679"
     CDS             1717..1935
                     /locus_tag="IT892_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheU family protein"
                     /protein_id="HAP3133921.1"
                     /translation="MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKR
                     QLQCGEAVLVWSELHETVNIMPRSQFRE"
     gene            1989..2858
                     /locus_tag="IT892_000680"
     CDS             1989..2858
                     /locus_tag="IT892_000680"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HAP3133922.1"
                     /translation="MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSF
                     HRYTRPEMDMAIRKARDAGRHISYFGPEANDFGLLEQTFIEYGQSGKGKSRKYLHTYD
                     EAVPWNQVPGTFTPWQPLPEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLE
                     WIQKLIRDTSERGHSREAVMDSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFA
                     AKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIML
                     PLVQRLMEGKKIE"
     gene            complement(2913..3317)
                     /locus_tag="IT892_000681"
     CDS             complement(2913..3317)
                     /locus_tag="IT892_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HAP3133923.1"
                     /translation="MQARVKWVEGLTFLGESASGHQILMDGNSGDKAPSPMEMVLMAA
                     GGCSAIDVVSILQKGRQDVVDCEVKLTSERREEAPRLFTHINLHFIVTGRDLKDAAVA
                     RAVDLSAEKYCSVALMLEKAVNITHSYEVVAA"
     gene            3619..4251
                     /gene="crp"
                     /locus_tag="IT892_000682"
     CDS             3619..4251
                     /gene="crp"
                     /locus_tag="IT892_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cAMP-activated global transcriptional regulator
                     CRP"
                     /protein_id="HAP3133924.1"
                     /translation="MVLGKTQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIV
                     KGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKK
                     FRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
                     PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR"
     gene            4302..6392
                     /locus_tag="IT892_000683"
     CDS             4302..6392
                     /locus_tag="IT892_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312236.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133925.1"
                     /translation="MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVP
                     ACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLLLAKDVPLPFLLTGLTLVLGVTA
                     ELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
                     LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLS
                     AQNNTDYKRMLRIFQEALDLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARL
                     RVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWHFSRIARVLRTQKPL
                     YARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWI
                     LMTVLLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASY
                     LILRKNYGWATVGFTITAVYTLQLLWLNGEQYILPRLIDTIIGCLIAFGGTVWLWPQW
                     QSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLNQAMQEP
                     AFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQ
                     RLEYDEPGSSGDANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPH
                     HGIWLSRKLRDSKA"
     gene            complement(6459..7679)
                     /gene="argD/dapC"
                     /locus_tag="IT892_000684"
     CDS             complement(6459..7679)
                     /gene="argD/dapC"
                     /locus_tag="IT892_000684"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     acetylornithine/succinyldiaminopimelate transaminase"
                     /protein_id="HAP3133926.1"
                     /translation="MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEY
                     VDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERV
                     VFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
                     FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQ
                     HQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAF
                     HPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSD
                     IRGMGLLIGAELKPQYKGRARDFLYAGAEAGVMVLNAGPDVMRFAPSLVVEDADIDEG
                     MQRFAHAVAKVVGA"
     gene            complement(7765..8328)
                     /gene="pabA"
                     /locus_tag="IT892_000685"
     CDS             complement(7765..8328)
                     /gene="pabA"
                     /locus_tag="IT892_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 2"
                     /protein_id="HAP3133927.1"
                     /translation="MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKP
                     QKIVISPGPCTPDEAGISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVMHG
                     KTSPITHNGEGVFRGLANPLTVTRYHSLVVEPDSLPACFDVTAWSETREIMGIRHRQW
                     DLEGVQFHPESILSEQGHQLLANFLHR"
     gene            complement(8360..8962)
                     /locus_tag="IT892_000686"
     CDS             complement(8360..8962)
                     /locus_tag="IT892_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenosine monophosphate-protein
                     transferase Fic"
                     /protein_id="HAP3133928.1"
                     /translation="MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRA
                     ATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNAL
                     MQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
                     SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE"
     gene            complement(8952..9119)
                     /locus_tag="IT892_000687"
     CDS             complement(8952..9119)
                     /locus_tag="IT892_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfG family protein"
                     /protein_id="HAP3133929.1"
                     /translation="MKKLTDKQKSRLWELQRNRNFQASRRLEGVEMPLVTLTAAEALA
                     RLEELRSHYER"
     gene            complement(9224..9796)
                     /gene="ppiA"
                     /locus_tag="IT892_000688"
                     /gene_synonym="rotA"
     CDS             complement(9224..9796)
                     /gene="ppiA"
                     /locus_tag="IT892_000688"
                     /gene_synonym="rotA"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase A"
                     /protein_id="HAP3133930.1"
                     /translation="MFKSTLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELEL
                     DKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEAD
                     NGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
                     KISQVPTHDVGPYQNVPSKPVVILSAKVLP"
     gene            10067..11248
                     /gene="tsgA"
                     /locus_tag="IT892_000689"
     CDS             10067..11248
                     /gene="tsgA"
                     /locus_tag="IT892_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter TsgA"
                     /protein_id="HAP3133931.1"
                     /translation="MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSS
                     MSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSAA
                     MFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSI
                     EWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCY
                     ILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTV
                     LAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVL
                     TCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTS
                     H"
     gene            11510..14053
                     /locus_tag="IT892_000690"
     CDS             11510..14053
                     /locus_tag="IT892_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase large subunit"
                     /protein_id="HAP3133932.1"
                     /translation="MSKVRLAIIGNGMVGHRFIEDLLDKSDAANFDITVFCEEPRIAY
                     DRVHLSSYFSHHTAEELSLVREGFYEKHGIKVLVGERAITINRQEKVIHSSAGRTVFY
                     DKLIMATGSYPWIPPIKGSDTQDCFVYRTIEDLNAIESCARRSKRGAVVGGGLLGLEA
                     AGALKNLGIETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGV
                     EARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLDVAPRGGIVINDSCQTSDPDI
                     YAIGECASWNNRVFGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLKLLGVDVGGIG
                     DAHGRTPGARSYVYLDESKEIYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIE
                     LPENPDSLILPAHSGSGKPSIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALK
                     AETKAGTGCGGCIPLVTQVLNAELAKQGIEVNNNLCEHFAYSRQELFHLIRVEGIKTF
                     EELLAKHGKGYGCEVCKPTVGSLLASCWNEYILKPEHTPLQDSNDNFLANIQKDGTYS
                     VIPRSPGGEITPEGLMAVGRIAREFNLYTKITGSQRLAMFGAQKDDLPEIWRQLIEAG
                     FETGHAYAKALRMAKTCVGSTWCRYGVGDSVGLGVELENRYKGIRTPHKMKFGVSGCT
                     RECSEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLLAADIDRETLIKYLDRFMMFY
                     IRTADKLTRTAPWLENLEGGIDYLKAVIIDDKLGLNAHLEEEMARLREAVLCEWTETV
                     NTPSAQTRFKHFINSDKRDPNVQMVPEREQHRPATPYERIPVTLVEDNA"
     gene            14050..14376
                     /gene="nirD"
                     /locus_tag="IT892_000691"
     CDS             14050..14376
                     /gene="nirD"
                     /locus_tag="IT892_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HAP3133933.1"
                     /translation="MSQWKDICKIDDILPETGVCALLGDEQVAIFRPYHSDQVFAISN
                     IDPFFESSVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYEARVKDG
                     VVQLRG"
     gene            14502..15308
                     /gene="nirC"
                     /locus_tag="IT892_000692"
     CDS             14502..15308
                     /gene="nirC"
                     /locus_tag="IT892_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026212.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite transporter NirC"
                     /protein_id="HAP3133934.1"
                     /translation="MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIIL
                     IFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTFGVKAGSISHGQMW
                     AILPQTWLGNLVGSVFVAMLYSWGGGSLLPVDTSIVHSVALAKTTAPAMVLFFKGALC
                     NWLVCLAIWMALRTEGAAKFIAIWWCLLAFIASGYEHSIANMTLFALSWFGNHSEAYT
                     LAGIGHNLLWVTLGNTLSGAVFMGLGYWYATPKANRPVADKFNQTETAAG"
     gene            15327..16700
                     /gene="cobA"
                     /locus_tag="IT892_000693"
     CDS             15327..16700
                     /gene="cobA"
                     /locus_tag="IT892_000693"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HAP3133935.1"
                     /translation="MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALA
                     FIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNV
                     VDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQ
                     LRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEV
                     VLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHC
                     VPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAAS
                     GCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQ
                     KLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDK
                     LNWFSNH"
     gene            16947..17114
                     /locus_tag="IT892_000694"
     CDS             16947..17114
                     /locus_tag="IT892_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfL family protein"
                     /protein_id="HAP3133936.1"
                     /translation="MNKFIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISIS
                     KIIGGCGPTAQ"
     gene            17358..18746
                     /gene="frlA"
                     /locus_tag="IT892_000695"
     CDS             17358..18746
                     /gene="frlA"
                     /locus_tag="IT892_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine/psicoselysine transporter"
                     /protein_id="HAP3133937.1"
                     /translation="MTANSPLQRIGQEKGIAMGSQELQRKLGFWAVLAIAVGTTVGSG
                     IFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGS
                     RPLAFLSGWASFWDNDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHL
                     RSVEGGAAFRTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGI
                     SATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKL
                     ANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFF
                     KCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWC
                     RKRDDYKPLWRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICAVIVIATGLPAYAF
                     WAKRSRQLNALS"
     gene            18767..19789
                     /gene="frlB"
                     /locus_tag="IT892_000696"
     CDS             18767..19789
                     /gene="frlB"
                     /locus_tag="IT892_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417830.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-phosphate deglycase"
                     /protein_id="HAP3133938.1"
                     /translation="MLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHAIVEEMVKRDI
                     DRIYFVACGSPLNAAQTAKHLADRFSDLQVYAISGWEFCDNTPYRLDDRCAVIGVSDY
                     GKTEEVIKALELGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHLLLCYSVV
                     LEMITRLAPNAEIGKIKNDLKQLPNALGHLVRTWEEKGRQLGELASQWPMIYTVAAGP
                     LRPLGYKEGIVTLMEFTWTHGCVIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTER
                     AINFVKQRTDNVIVIDYAEISQGLHPWLAPFLMFVPMEWLCYYLSIYKDHNPDERRYY
                     GGLVEY"
     gene            19839..20669
                     /gene="frlC"
                     /locus_tag="IT892_000697"
     CDS             19839..20669
                     /gene="frlC"
                     /locus_tag="IT892_000697"
                     /EC_number="5.1.3.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 3-epimerase"
                     /protein_id="HAP3133939.1"
                     /translation="MKTGMFTCGHQRLPIEHAFRDASELGYDGIEIWGGRPHAFAPDL
                     KAGGIKQIKALAQTYQMPIIGYTPETNGYPYNMMLGDEHMRRESLDMIKLAMDMAKEM
                     NAGYTLISAAHAGYLTPPNVIWGRLAENLSELCEYAENIGMDLILEPLTPYESNVVCN
                     ANDVLHALALVPSPRLFSMVDICAPYVQAEPVMSYFDKLGDKLRHLHIVDSDGASDTH
                     YIPGEGKMPLRELMRDIIERGYEGYCTVELVTMYMNEPRLYARQALERFRALLPEDER
                     "
     gene            20666..21451
                     /gene="frlD"
                     /locus_tag="IT892_000698"
     CDS             20666..21451
                     /gene="frlD"
                     /locus_tag="IT892_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAP3133940.1"
                     /translation="MKTLATIGDNCVDIYPQLNKAFSGGNAVNVAVYCTRYGIQPGCI
                     TWVGDDDYGTKLKQDLARMGVDISHVHTKHGVTAQTQVELHDNDRVFGDYTEGVMADF
                     ALSEEDYAWLAQYDIVHAAIWGHAEDAFPQLHAAGKLTAFDFSDKWDSPLWQTLVPHL
                     DFAFASAPQEDETLRLKMKAIVARGAGTVIVTLGENGSIAWDGAQFWRQAPEPVTVID
                     TMGAGDSFIAGFLCGWSAGMTLPQAIAQGTACAAKTIQYHGAW"
     gene            21551..22282
                     /gene="phoB"
                     /locus_tag="IT892_000699"
     CDS             21551..22282
                     /gene="phoB"
                     /locus_tag="IT892_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417834.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator PhoB"
                     /protein_id="HAP3133941.1"
                     /translation="MSATDRYSHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQ
                     YNVSRITIRKAISDLVADGVLIRWQGKGTFVQSQKVENALLTVSGFTDFGVSQGKATK
                     EKVIEQERVSAAPFCEKLNIPGNSEVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEI
                     YVEGSSTYQLFQERFDTRVVSDKKTIDIFAATRPRAKWLKCELGEPLFRISKIAFDQN
                     DKPVHVSELFCRANRITLTIDNKRH"
     gene            complement(22434..23519)
                     /locus_tag="IT892_000700"
     CDS             complement(22434..23519)
                     /locus_tag="IT892_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAP3133942.1"
                     /translation="MKTFPLQSLTIIEAQQKQFALVDSICRHFPGSEFLTGGDLGLTP
                     GLNQPRVTQRVEQVLADAFHAQAAALVQGAGTGAIRAGLAALLKPGQRLLVHDAPVYP
                     TTRVIIEQMGLTLITVDFNDLSALKQVVDEQQPDAALVQHTRQQPQDSYVLADVLATL
                     RAAGVPALTDDNYAVMKVARIGCECGANVSTFSCFKLFGPEGVGAVVGDADVINRIRA
                     TLYSSGSQIQGAQALEVLRGLVFAPVMHAVQAGVSERLLALLNGGAVPEVKSAVIANA
                     QSKVLIVEFHQPIAARVLEEAQKRGALPYPVGAESKYEIPPLFYRLSGTFRQANPQSE
                     HCAIRINPNRSGEETVLRILRESIASI"
     gene            complement(23531..24835)
                     /locus_tag="IT892_000701"
     CDS             complement(23531..24835)
                     /locus_tag="IT892_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133943.1"
                     /translation="MDLYIQIIVVACLTGMTSLLAHRSAAVFHDGIRPILPQLIEGYM
                     NRREAGSIAFGLSIGFVASVGISFTLKTGLLNAWLLFLPTDILGVLAINSLMAFGLGA
                     IWGVLILTCLLPVNQLLTALPVDVLGSLGELSSPVVSAFALFPLVAIFYQFGWKQSLI
                     AAVVVLMTRVVVVRYFPHLNPESIEIFIGMVMLLGIAITHDLRHRDENDIDASGLSVF
                     EERTSRIIKNLPYIAIVGALIAAVASMKIFAGSEVSIFTLEKAYSAGVTPEQSQTLIN
                     QAALAEFMRGLGFVPLIATTALATGVYAVAGFTFVYAVGYLSPNPMVAAVLGAVVISA
                     EVLLLRSIGKWLGRYPSVRNASDNIRNAMNMLMEVALLVGSIFAAIKMAGYTGFSIAV
                     AIYFLNESLGRPVQKMAAPVVAVMITGILLNVLYWLGLFVPA"
     gene            complement(24847..25200)
                     /locus_tag="IT892_000702"
     CDS             complement(24847..25200)
                     /locus_tag="IT892_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2620 domain-containing protein"
                     /protein_id="HAP3133944.1"
                     /translation="MKKIGVAGLQREQIKKTIEATAPGCFEVFIHNDMEAAMKVKSGQ
                     LDYYIGACNTGAGAALSIAIAVIGYNKSCTIAKPGIKAKDEHIAKMIAEGKVAFGLSV
                     EHVEHAIPMLINHLK"
     gene            complement(25211..26089)
                     /locus_tag="IT892_000703"
     CDS             complement(25211..26089)
                     /locus_tag="IT892_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase-related protein"
                     /protein_id="HAP3133945.1"
                     /translation="MSFDPTGYTLAHEHLHIDLSGFKNNVDCRLDQYAFICQEMNDLM
                     TRGVRNVIEMTNRYMGRNAQFMLDVMRETGINVVACTGYYQDAFFPEHVATRSVQELA
                     QEMVDEIEQGIDGTELKAGIIAEIGTSEGKITPLEEKVFIAAALAHNQTGRPISTHTS
                     FSTMGLEQLALLQAHGVDLSRVTVGHCDLKDNLDNILKMIDLGAYVQFDTIGKNSYYP
                     DEKRIAMLHALRDRGLLNRVMLSMDITRRSHLKANGGYGYDYLLTTFIPQLRQSGFSQ
                     ADVDVMLRENPSQFFQ"
     gene            complement(26086..27312)
                     /locus_tag="IT892_000704"
     CDS             complement(26086..27312)
                     /locus_tag="IT892_000704"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAP3133946.1"
                     /translation="MARFVVLVIDSFGVGAMKDVTLVRPQDAGANTCGHILSQLPHLQ
                     LPTLEKLGLINALGYAPGDMQPSDSATWGVAELQHEGGDTFMGHQEILGTRPLPPLRM
                     PFRDVIDRVEQALVSAGWQVERRGDDLQFLWVNQAVAIGDNLEADLGQVYNITANLSV
                     ISFDDAIKIGRIVREQVQVGRVITFGGLLTDSQRILDAAESKEGRFIGINAPRSGAYD
                     NGFQVVHMGYGVDEKVQVPQKLYEAGVPTVLVGKVADIVNNPYGVSWQNLVDSQRIMD
                     ITLNEFNTHPTAFICTNIQETDLAGHAEDVARYAERLQVVDRNLARLVEAMQPDDCLV
                     VMADHGNDPTIGHSHHTREVVPVLVYQQGMIATQLGVRTTLSDVGATVCEFFRAPPPQ
                     NGRSFLSSLRFAGDTL"
     gene            complement(27312..28475)
                     /locus_tag="IT892_000705"
     CDS             complement(27312..28475)
                     /locus_tag="IT892_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfX family PLP-dependent enzyme"
                     /protein_id="HAP3133947.1"
                     /translation="MFVEALKRQNPALISAALSLWQQGKIAPDSWVIDVDQILENGKR
                     LIETARLYGIELYLMTKQFGRNPWLAEKLLALGYSGIVAVDYKEARVMRRAGLPVAHQ
                     GHLVQIPCHQVADAVEQGTDVITVFTLDKAREVSAAAVKAGRIQSVLLKVYSDDDFLY
                     PGQESGFALKVLPEIVAEIQNLPGLHLAGLTHFPCLLWDEAVGKVLPTPNLHTLIQAR
                     DQLAKSGIALEQLNAPSATSCTSLPLLAQYGVTHAEPGHALTGTIPANQQGDQPERIA
                     MLWLSEISHHFRGDSYCYGGGYYRRGHAQHALVFTPENQKITETNLKTVDDSSIDYTL
                     PLAGEFPVSSAVVLCFRTQIFVTRSDVVLVSGIHRGEPEIVGRYDSLGNSLGA"
     gene            complement(28559..28921)
                     /locus_tag="IT892_000706"
     CDS             complement(28559..28921)
                     /locus_tag="IT892_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417841.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP3133948.1"
                     /translation="METRLNLLCEAGVIDKDICKGMMQVVNVLETECHLPVRSEQGTM
                     AMTHMASALMRSRRGEEIEPLDNELLAELAQSSHWQAVVQLHQVLLKEFALEVNPCEE
                     GYLLANLYGLWMAANEEV"
     gene            complement(28938..29843)
                     /locus_tag="IT892_000707"
     CDS             complement(28938..29843)
                     /locus_tag="IT892_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3133949.1"
                     /translation="MRRTFIKKEGVVITTLARYLLGEKCGNRLKTIDELANECRSSVG
                     LTQAALKTLESSGAIRIERRGRNGSYLVEMDNKALLTHVDINNVVCAMPLPYTRLYEG
                     LASGLKAQFDGIPFYYAHMRGADIRVECLLNGVYDMAVVSRLAAESYLTQKGLCLALE
                     LGPHTYVGEHQLICRKGESANVKRVGLDNRSADQKIMTDVFFGGSDVERVDLSYHESL
                     QRIVKGDVDAVIWNVVAENELTMLGLEATPLTDDPRFLQATEAVVLTRVDDYPMQQLL
                     RAVVDKHALLAHQQRVVSGEQEPSY"
     gene            complement(30133..31137)
                     /gene="trpS"
                     /locus_tag="IT892_000708"
     CDS             complement(30133..31137)
                     /gene="trpS"
                     /locus_tag="IT892_000708"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAP3133950.1"
                     /translation="MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQ
                     HAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFG
                     ELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
                     AQRFNALYGEIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVK
                     KIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGE
                     VADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKP
                     "
     gene            complement(31130..31888)
                     /gene="gph"
                     /locus_tag="IT892_000709"
     CDS             complement(31130..31888)
                     /gene="gph"
                     /locus_tag="IT892_000709"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HAP3133951.1"
                     /translation="MNKFEDIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEE
                     RVITWIGNGADVLMERALTWARQERATQRKTMGKPPVDDDIPAEEQVRILRKLFDRYY
                     GEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGG
                     DDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGE
                     AIDLSQPDVIYQSINDLLPALGLPHSENQESKND"
     gene            complement(31881..32558)
                     /gene="rpe"
                     /locus_tag="IT892_000710"
     CDS             complement(31881..32558)
                     /gene="rpe"
                     /locus_tag="IT892_000710"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAP3133952.1"
                     /translation="MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVP
                     NLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRT
                     LQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
                     VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSE
                     LAKVSHE"
     gene            complement(32576..33412)
                     /gene="dam"
                     /locus_tag="IT892_000711"
     CDS             complement(32576..33412)
                     /gene="dam"
                     /locus_tag="IT892_000711"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HAP3133953.1"
                     /translation="MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLN
                     TDFSRYILADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQ
                     DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFF
                     YCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVE
                     RHIPVLISNHDTMLTREWYQRAKLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPA
                     KK"
     gene            complement(33519..34805)
                     /gene="damX"
                     /locus_tag="IT892_000712"
     CDS             complement(33519..34805)
                     /gene="damX"
                     /locus_tag="IT892_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DamX"
                     /protein_id="HAP3133954.1"
                     /translation="MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDI
                     ELDDTDDRRPTRAQKERNEEPEIEEEIDESEDETVDEERVERRPRKRKKAASKPASRQ
                     YMMMGVGILVLLLLIIGIGSALKAPSTTSSDQTASGEKSIDLAGNATDQANGVQPAPG
                     TTSAENTQQDVSLPPISSTPTQGQTPVATDGQQRVEVQGDLNNALTQPQNQQQLNNVA
                     VNSTLPTEPATVAPVRNGNASRDTAKTQTAERPSTTRPARQQAVIEPKKPQATVKTEP
                     KPVAQTPKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASPAQTTATPAAGAKTA
                     GNVGSLKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVSGV
                     YASKEEAKKAVSTLPADVQAKNPWAKPLRQVQADLK"
     gene            complement(34897..35985)
                     /gene="aroB"
                     /locus_tag="IT892_000713"
     CDS             complement(34897..35985)
                     /gene="aroB"
                     /locus_tag="IT892_000713"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAP3133955.1"
                     /translation="MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNET
                     LAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVAL
                     GGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
                     ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYC
                     IRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAA
                     RTSERLGQFSSAETQRIITLLKRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLIL
                     PLAIGKSEVRSGVSHELVLNAIADCQSA"
     gene            complement(36042..36563)
                     /gene="aroK"
                     /locus_tag="IT892_000714"
     CDS             complement(36042..36563)
                     /gene="aroK"
                     /locus_tag="IT892_000714"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004709337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroK"
                     /protein_id="HAP3133956.1"
                     /translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTG
                     ADVGWVFDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVY
                     LETTIEKQLARTQRDKKRPLLHVETPPREVLEALANERNPLYEEIADVTIRTDDQSAK
                     VVANQIIHMLESN"
     gene            complement(36964..38202)
                     /gene="hofQ"
                     /locus_tag="IT892_000715"
     CDS             complement(36964..38202)
                     /gene="hofQ"
                     /locus_tag="IT892_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA uptake porin HofQ"
                     /protein_id="HAP3133957.1"
                     /translation="MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQE
                     KLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSVHSIAWQNNNIA
                     RQEAEQARAQANLPLENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
                     KTALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTT
                     LGSDLSVATATTHVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIK
                     QGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQA
                     DGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDG
                     KEDERRELVVFITPRLVSSE"
     gene            complement(38114..38518)
                     /gene="hofP"
                     /locus_tag="IT892_000716"
     CDS             complement(38114..38518)
                     /gene="hofP"
                     /locus_tag="IT892_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417851.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofP"
                     /protein_id="HAP3133958.1"
                     /translation="MRVKRWLLAGIALCLLTGMRDPFKPPEDLCRISELSQWRYQGMV
                     GRGERIIGVIKDGQKKWRRVQQNDVLENGWTILQLTPDVLTLGTGTNCEPPQWLWQRQ
                     GDTNEAMDSRTTVDADTRRTGGKAAKSDADGG"
     gene            complement(38508..38948)
                     /gene="hofO"
                     /locus_tag="IT892_000717"
     CDS             complement(38508..38948)
                     /gene="hofO"
                     /locus_tag="IT892_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofO"
                     /protein_id="HAP3133959.1"
                     /translation="MNMFFDWWFATSPRLRQLCWAFWLLMLVTLIFLSSTHHEERDAL
                     IRLRASHHQQWAALYRLVDTTPFSEEKTLPFSPLDFQLSGAQLVSWHPSAQGGELALK
                     TLWEAVPSAFTRLAERNVSVSRFSLSVEGDDLLFTLQLETPHEG"
     gene            complement(38932..39471)
                     /locus_tag="IT892_000718"
     CDS             complement(38932..39471)
                     /locus_tag="IT892_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofN"
                     /protein_id="HAP3133960.1"
                     /translation="MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTG
                     SAEARIDAVLLQAEQQLARSLQITKPRLLEQQQLREQRSQRQRQRQFTRDWQSALEAL
                     AALLPEHAWLTTISWQQGTLEIKGLTTSITALNALETSLRQDASFHLNQRGATQQDAQ
                     GRWQFEYQLTRKVSDEHVL"
     gene            complement(39471..40250)
                     /gene="hofM"
                     /locus_tag="IT892_000719"
     CDS             complement(39471..40250)
                     /gene="hofM"
                     /locus_tag="IT892_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofM"
                     /protein_id="HAP3133961.1"
                     /translation="MAFKIWQIGLHLQQQEAVAVAIVRGAKECFLQRWWRLPLENDII
                     KDGRIVDAQQLAKTLLPWSRELPQRHHIMLAFPASRTLQRSFPRPSMSLGEREQTAWL
                     SGTMARELDMDPDSLRFDYSEDSLSPAYNVTAAQSKELATLLTLAERLRVHVSAITPD
                     ASALQRFLPFLPSHQQCLAWRDNEQWLWATRYSWGRKLAVGMTSAKELAAALSVDPES
                     VAICGEGGFDPWEAVSVRQPPLPPPGGDFAIALGLALGKAY"
     gene            40370..42922
                     /gene="mrcA"
                     /locus_tag="IT892_000720"
     CDS             40370..42922
                     /gene="mrcA"
                     /locus_tag="IT892_000720"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417855.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /protein_id="HAP3133962.1"
                     /translation="MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRL
                     QIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIF
                     RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL
                     ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRA
                     VARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRY
                     GESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNN
                     KITDTLKALPTYGPLLPAAVTSANPQQATAMLADGSTVALSMEGVRWARPYRSDTQQG
                     PTPRKVTDVLQTGQQIWVRQVGDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQ
                     SKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDASAGSDWQPKNSP
                     PQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSA
                     SFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDT
                     QKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFL
                     IKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVW
                     IGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG
                     IVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF"
     gene            complement(43088..43648)
                     /gene="nudE"
                     /locus_tag="IT892_000721"
     CDS             complement(43088..43648)
                     /gene="nudE"
                     /locus_tag="IT892_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP compounds hydrolase NudE"
                     /protein_id="HAP3133963.1"
                     /translation="MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRP
                     TNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGF
                     GANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLE
                     DPDFNEARNVSALFLVREWLKGQGRV"
     gene            43968..46103
                     /gene="igaA"
                     /locus_tag="IT892_000722"
     CDS             43968..46103
                     /gene="igaA"
                     /locus_tag="IT892_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular growth attenuator protein IgaA"
                     /protein_id="HAP3133964.1"
                     /translation="MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRK
                     LTPEERSAVENYLESLTQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGIST
                     DDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETR
                     SYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFF
                     CLITPDVFVPWLTGGALLLLGAGLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQE
                     QINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHVVRQGRYLSLHDEVKNFPL
                     QHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRV
                     GDTLRISGTGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATAL
                     TEAVNRQLHPKPEDESRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCSAKDDCVRLK
                     NALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFITHETARA
                     AQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNA
                     EGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQR
                     HRTRMMEIQAYYESCLNPQLITPSESLIE"
     gene            46168..46836
                     /gene="yrfG"
                     /locus_tag="IT892_000723"
     CDS             46168..46836
                     /gene="yrfG"
                     /locus_tag="IT892_000723"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP/IMP nucleotidase"
                     /protein_id="HAP3133965.1"
                     /translation="MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNG
                     VTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFL
                     EALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAE
                     ATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLI
                     PSLM"
     gene            46847..47248
                     /gene="hslR"
                     /locus_tag="IT892_000724"
     CDS             46847..47248
                     /gene="hslR"
                     /locus_tag="IT892_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated heat shock protein Hsp15"
                     /protein_id="HAP3133966.1"
                     /translation="MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSK
                     PSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAALLYEETAESVEKREKMALAR
                     KLNALTMPHPDRRPDKKERRDLLRFKHGDSE"
     gene            47273..48151
                     /gene="hslO"
                     /locus_tag="IT892_000725"
     CDS             47273..48151
                     /gene="hslO"
                     /locus_tag="IT892_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAP3133967.1"
                     /translation="MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNV
                     LAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENA
                     DLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGD
                     VDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEV
                     TVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMD
                     IAEIRNNASPADPQVH"
     gene            complement(48214..49938)
                     /locus_tag="IT892_000726"
     CDS             complement(48214..49938)
                     /locus_tag="IT892_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4153 domain-containing protein"
                     /protein_id="HAP3133968.1"
                     /translation="MDNVELSPATRWGMIATGLLQGLVCYLLIAWLSGKNHSWIVYGV
                     PATVAFSSVLLFSVISFKQKRLWGWLALVFIATLGMSGWLKWQTDGMNPWRAEKALWD
                     FGCYLLLMAMLLLPWIQQSLRIRNDSSRYRYFYQSVWHNVLILLVIFLANGLTWLVLL
                     LWSELFKLVGITFFNTLFFATDWFIYLTLGLVTALAVILARTQSRLIDSIQKLFTLIA
                     TGLLPLVSLLTLMFIITLPFTGLSAISRHISAAGLLLTLAFLQLILMAIVRDPQKASL
                     PWTGPLRCLIKTALLVAPLYVFVAAWALWLRVAQYGWTVDRLQGVLAVLVLLVWSLGY
                     FVSIVWRKGQNPVVLQGKVNLAVSLLVLVILVLLNSPVLDSMRISVNSHMARYQSGKN
                     TSDQVTIYMLEQSGRYGRAALESLKSDAGFMKDPKRARDLLMALDGEQHLQQQVSEKV
                     LADNVLIAPGSVKPDATFWSALIQDRYNVMTCIEKDACVLVEQDLNSDGQAERILFAF
                     NDDRVIVYGFDSDRKEWDALDMSLLPNEITKEKLLTAAKDGKLGTKPKAWRDLVVDGE
                     RLNVNLNE"
     gene            50317..51939
                     /gene="pckA"
                     /locus_tag="IT892_000727"
     CDS             50317..51939
                     /gene="pckA"
                     /locus_tag="IT892_000727"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAP3133969.1"
                     /translation="MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGY
                     ERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETW
                     QHLKGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEEL
                     AGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSM
                     MNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDD
                     GVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRV
                     SYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLA
                     GTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRI
                     SIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQE
                     KAETLAKLFIDNFDKYTDTPAGAALVAAGPKL"
     gene            complement(52015..53367)
                     /gene="envZ"
                     /locus_tag="IT892_000728"
     CDS             complement(52015..53367)
                     /gene="envZ"
                     /locus_tag="IT892_000728"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /protein_id="HAP3133970.1"
                     /translation="MRRLRFSPRSSFARTLLLIVTLLFASLVTTYLVVLNFAILPSLQ
                     QFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYSNEAAEEAGLRWA
                     QHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
                     FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTR
                     AFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEE
                     CNAIIEQFIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIETALYPGSIEVKMHP
                     LSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVR
                     GDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTKEG
                     "
     gene            complement(53364..54083)
                     /gene="ompR"
                     /locus_tag="IT892_000729"
     CDS             complement(53364..54083)
                     /gene="ompR"
                     /locus_tag="IT892_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018150685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HAP3133971.1"
                     /translation="MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLL
                     TRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDY
                     IPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
                     LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAH
                     PRYIQTVWGLGYVFVPDGSKA"
     gene            54275..54787
                     /gene="greB"
                     /locus_tag="IT892_000730"
     CDS             54275..54787
                     /gene="greB"
                     /locus_tag="IT892_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709179.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HAP3133972.1"
                     /translation="MRIIKQTKGINEMKTPLVTREGYEKLKQELNYLWREERPEVTKK
                     VTWAASLGDRSENADYQYNKKRLREIDRRVRYLTKCLENLKIVDYSPQQEGKVFFGAW
                     VEIENDDGVTHRFRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPAGEASW
                     YVNAIEYVKP"
     gene            54884..57205
                     /locus_tag="IT892_000731"
     CDS             54884..57205
                     /locus_tag="IT892_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417866.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAP3133973.1"
                     /translation="MMNDSFCRIIAGEIQARPEQVDAAVRLLDEGNTVPFIARYRKEI
                     TGGLDDTQLRNLETRLSYLRELEERRQAILKSISEQGKLTDDLAKAINATLSKTELED
                     LYLPYKPKRRTRGQIAIEAGLEPLADLLWSDPSHTPEVAAAQYVDADKGVADTKAALD
                     GARYILMERFAEDAALLAKVRDYLWKNAHLVSTVVSGKEEEGAKFRDYFDHHEPLSTV
                     PSHRALAMFRGRNEGVLQLSLNADPQFDEPPKESYCEQIIMDHLGLRLNNAPADSWRK
                     GVVSWTWRIKVLMHLETELMGTVRERAEDEAINVFARNLHDLLMAAPAGLRATMGLDP
                     GLRTGVKVAVVDATGKLVATDTIYPHTGQAAKAAMTVAALCEKHNVELVAIGNGTASR
                     ETERFYLDVQKQFPKVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRL
                     QDPLAELVKIDPKSIGVGQYQHDVSQTQLARKLDAVVEDCVNAVGVDLNTASVPLLTR
                     VAGLTRMMAQNIVAWRDENGQFQNRQQLLKVSRLGPKAFEQCAGFLRINHGDNPLDAS
                     TVHPEAYPVVERILAATQQALKDLMGNSSELRNLKASDFTDEKFGVPTVTDIIKELEK
                     PGRDPRPEFKTAQFADGVETMNDLQPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISS
                     LSNKFVEDPHTVVKAGDIVKVKVLEVDLQRKRIALTMRLDEQPGETNARRGGGNERPQ
                     NNRPAAKPRGREAQPAGNSAMMDALAAAMGKKR"
     gene            57662..57889
                     /gene="feoA"
                     /locus_tag="IT892_000732"
     CDS             57662..57889
                     /gene="feoA"
                     /locus_tag="IT892_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HAP3133974.1"
                     /translation="MQYTPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAP
                     LGDPIHIETRRVSLVLRKKDLALLEVEAVSC"
     gene            57906..60227
                     /gene="feoB"
                     /locus_tag="IT892_000733"
     CDS             57906..60227
                     /gene="feoB"
                     /locus_tag="IT892_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HAP3133975.1"
                     /translation="MKKLTIGLIGNPNSGKTTLFNQLTGSRQRVGNWAGVTVERKEGQ
                     FSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNL
                     YLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
                     LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAY
                     AGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDK
                     IVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDW
                     LTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGK
                     SFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQN
                     GALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRL
                     KGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHED
                     NWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAIDETWQSL
                     KDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMG
                     AIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQHPTYSLVCILAVILFNIVVIG
                     LLRRARSRVDIELLATRKSVSSCCAASTTGDCH"
     gene            60227..60463
                     /gene="feoC"
                     /locus_tag="IT892_000734"
     CDS             60227..60463
                     /gene="feoC"
                     /locus_tag="IT892_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-S]-dependent transcriptional repressor FeoC"
                     /protein_id="HAP3133976.1"
                     /translation="MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMG
                     KAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR"
     gene            60666..61544
                     /gene="rpnA"
                     /locus_tag="IT892_000735"
     CDS             60666..61544
                     /gene="rpnA"
                     /locus_tag="IT892_000735"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnA"
                     /protein_id="HAP3133977.1"
                     /translation="MSKKQSSTPHDALFKLFLRQPDTARDFLAFHLPAPIHALCDMKT
                     LKLESSSFIDDDLRESYSDVLWSVKTEQGPGYIYCLIEHQSTSNKLIAFRMMRYAIAA
                     MQNHLDAGYKTLPMVVPLLFYHGIESPYPYSLCWLDCFADPKLARQLYASAFPLIDVT
                     VMPDDEIMQHRRMALLELIQKHIRQRDLMGLVEQMACLLSSGYANDRQIKGLFNYILQ
                     TGDAVRFNDFIDGVAERSPKHKESLMTIAERLRQEGEQSKALHIAKIMLESGVPLADI
                     MRFTGLSEEELAAASQ"
     gene            complement(61573..62343)
                     /gene="bioH"
                     /locus_tag="IT892_000736"
     CDS             complement(61573..62343)
                     /gene="bioH"
                     /locus_tag="IT892_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HAP3133978.1"
                     /translation="MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHL
                     VDLPGFGRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQAL
                     VTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARA
                     LKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPML
                     DKLWPHSESYIFAKAAHAPFISHPAEFCHLLVALKQRV"
     gene            62381..63064
                     /gene="gntX"
                     /locus_tag="IT892_000737"
     CDS             62381..63064
                     /gene="gntX"
                     /locus_tag="IT892_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417872.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein GntX"
                     /protein_id="HAP3133979.1"
                     /translation="MLTVPGLCWLCRMPLALGHWGICSVCSRATRTDKTLCPQCGLPA
                     THSHLPCGRCLQKPPPWQRLVTVADYAPPLSPLIHQLKFSRRSEIASALSRLLLLEVL
                     HARRTTGLQLPDRIVSVPLWQRRHWRRGFNQSDLLCQPLSRWLHCQWDSEAVTRTRAT
                     ATQHFLSARLRKRNLKNAFRLELPVQGRHMVIVDDVVTTGSTVAEIAQLLLRNGAAAV
                     QVWCLCRTL"
     gene            63123..63698
                     /gene="nfuA"
                     /locus_tag="IT892_000738"
     CDS             63123..63698
                     /gene="nfuA"
                     /locus_tag="IT892_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016942932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S biogenesis protein NfuA"
                     /protein_id="HAP3133980.1"
                     /translation="MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYC
                     PPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVA
                     DDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLK
                     EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY"
     gene            64058..65374
                     /gene="gntT"
                     /locus_tag="IT892_000739"
     CDS             64058..65374
                     /gene="gntT"
                     /locus_tag="IT892_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HAP3133981.1"
                     /translation="MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLD
                     KVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVV
                     LTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGP
                     TAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEE
                     MPSFGVSVWTSLVPVVLMAMRAIAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFT
                     FGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNI
                     SPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSH
                     VNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI"
     gene            complement(65485..67569)
                     /gene="malQ"
                     /locus_tag="IT892_000740"
     CDS             complement(65485..67569)
                     /gene="malQ"
                     /locus_tag="IT892_000740"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HAP3133982.1"
                     /translation="MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQR
                     TATKVAVTPVPNVMVYTSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPT
                     KLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWG
                     IGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNA
                     VEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDE
                     QMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFC
                     EEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDREL
                     YCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHV
                     MSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGK
                     LRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWESGDLTLGKT
                     LGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRY
                     IADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWRRKLSATLESMFADDGVNKLLKD
                     LDRRRRAAAKKK"
     gene            complement(67579..69972)
                     /gene="malP"
                     /locus_tag="IT892_000741"
     CDS             complement(67579..69972)
                     /gene="malP"
                     /locus_tag="IT892_000741"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="HAP3133983.1"
                     /translation="MSQPIFNDKQFQEALSRQWQRYGLNSAAEMTPRQWWLAVSEALA
                     EMLRAQPFAKPVANQRHVNYISMEFLIGRLTGNNLLNLGWYQDVQDSLKAYDINLTDL
                     LEEEIDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVDGKQVEAPD
                     DWHRSNYPWFRHNEALDVQVGIGGKVTKDGRWEPEFTITGQAWDLPVVGYRNGVAQPL
                     RLWQATHAHPFDLTKFNDGDFLRAEQQGINAEKLTKVLYPNDNHTAGKKLRLMQQYFQ
                     CACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRVLIDEHQMSWDDAW
                     AITSKTFAYTNHTLMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEK
                     VWAKLAVVHDKQVHMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTN
                     GITPRRWIKQCNPALAALLDKSLQKEWANDLDQLINLEKFADDAKFRQQYREIKQANK
                     VRLAEFVKVRTGIEINPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVP
                     RVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIP
                     AADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVE
                     QVKAILAKGYDPVKWRKKDKVLDAVLKELESGKYSDGDKHAFDQMLHSIGKQGGDPYL
                     VMADFAAYVEAQKQVDVLYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR"
     gene            70584..73289
                     /gene="malT"
                     /locus_tag="IT892_000742"
     CDS             70584..73289
                     /gene="malT"
                     /locus_tag="IT892_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MalT"
                     /protein_id="HAP3133984.1"
                     /translation="MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYG
                     KTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQY
                     ASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR
                     NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGW
                     ATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAI
                     LRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQW
                     ELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSL
                     LEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAE
                     FNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSL
                     ALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQL
                     PMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGD
                     LDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFA
                     NNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQ
                     AGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRI
                     LREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQI
                     AGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV"
     gene            complement(73332..74348)
                     /gene="rtcA"
                     /locus_tag="IT892_000743"
     CDS             complement(73332..74348)
                     /gene="rtcA"
                     /locus_tag="IT892_000743"
                     /EC_number="6.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 3'-terminal phosphate cyclase"
                     /protein_id="HAP3133985.1"
                     /translation="MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAK
                     PGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVL
                     QTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFY
                     PAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSL
                     HEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLAS
                     TAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFSLIETDGVTR
                     VSIE"
     gene            complement(74352..75536)
                     /locus_tag="IT892_000744"
     CDS             complement(74352..75536)
                     /locus_tag="IT892_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
                     /protein_id="HAP3133986.1"
                     /translation="MWTKGVPVEADARQQLINTAKMPFIFKHIAVMPDVHLGKGSTIG
                     SVIPTKGAIIPAAVGVDIGCGMNALRTALTAEDLPENLAELRQAIETAVPHGRTTGRC
                     KRDKGAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHLGTLGTGNHFIEICL
                     DESDQVWIMLHSGSRGIGNAIGTYFIDLAQKEMQETLETLPSRDLAYFMEGTEYFDDY
                     LKAVAWAQLFASLNRDAMMENVVTALQSITQKTVRQPQTLAMEEINCHHNYVQKEQHF
                     GEEIYVTRKGAVSARAGQYGIIPGSMGAKSFIVRGLGNEESFCSCSHGAGRVMSRTKA
                     KKLFSVEDQIRATAHVECRKDAEVIDEIPMAYKDIDAVMAAQSDLVEVIYTLRQVVCV
                     KG"
BASE COUNT        17940 a        20624 c        19255 g        17757 t
ORIGIN      
        1 agctggaaca aaaactgcgt gactacctcg gcggctttgg tttccagggc gataaagtaa
       61 ccgaagaaac gcgccgcttc tccggtgggg aaaaagcccg cctggtgctg gcattaattg
      121 tctggcagcg gccgaatctg ctgctgctcg acgaaccgac taaccacctt gacctcgaca
      181 tgcgtcaggc actcaccgaa gcattaatcg agtttgaagg cgcgctggtt gtcgtttcgc
      241 acgaccgtca tttgctgcgt tccaccactg acgatctcta cctggttcac gatcgtaaag
      301 tcgaaccgtt cgacggcgat ctggaagatt atcaacagtg gttgagcgac gtacaaaagc
      361 aggaaaacca gaccgacgaa gcgccaaaag agaatgcgaa cagcgcccag gcacgtaaag
      421 atcagaagcg tcgggaagct gagctgcgtg cgcaaaccca gccactgcgt aaagagattg
      481 cccgtctgga aaaagagatg gagaagctga acgcgcaact ggcgcaggcg gaagagaaac
      541 tcggcgacag cgaactgtat gaccagagcc gtaaagcgga gttgaccgcc tgcctgcaac
      601 agcaagccag cgccaaatcc ggcctggaag agtgcgaaat ggcatggctg gaagcccagg
      661 agcagcttga gcagatgctg ctggaaggcc aaagcaactg atggcgcaga taacgacgac
      721 cgatgccaat gaattcagca gcagtgctga attcatcccc atgcgcggct ttagcaattg
      781 tcatctgcaa accatgctgc cgcgtctgtt tcgtcgtcag gtgaaattca ccccgtactg
      841 gcagcggctg gagttgcccg acggcgattt tgtcgatctt gcgtggagtg aaaaccctgc
      901 acaggcgcaa cataaacctc gtctggtggt gtttcacggg ctggaaggca gtctcaacag
      961 cccttacgcc cacggtctgg ttgaggcggc gcaaaagcgc ggctggctgg gcgtggtgat
     1021 gcattttcgc ggatgcagcg gtgaaccaaa ccgtatgcac cgcatttacc attcgggcga
     1081 aaccgaagac gccagttggt ttttacgctg gctgcaacgc gaatttggtc atgcgccaac
     1141 ggctgccgtc ggctattcgc tcggcggtaa tatgctggcc tgtttgctgg caaaggaagg
     1201 caatgatctc ccggttgatg cggcggtgat tgtctctgcg ccgtttatgc tggaagcctg
     1261 tagctatcat atggaaaagg gcttttcccg cgtttatcag cgttacttgc tgaacctgtt
     1321 aaaagccaat gccgcgcgca agctggcagc ctaccccgga acgctgccga ttaatctcgc
     1381 gcagttaaaa tcggtacgtc gcatccgtga atttgacgat ctcatcaccg ccagaattca
     1441 cggctacgcc gacgctatcg actattatcg tcagtgtagc gccatgccga tgctgaaccg
     1501 gatcgccaaa ccgacgctga ttattcacgc caaagacgat ccgtttatgg atcatcaggt
     1561 gatcccgaaa ccggaaagtc tccccccgca ggtggagtat caactgactg aacatggcgg
     1621 tcatgttggc tttattggcg gtacattact tcatccacaa atgtggctgg agtcacgcat
     1681 tcctgactgg ttaacaacgt atctggaggc gaaatcatgt tgattccgtg gcaagacctc
     1741 tcccccgaaa cgctggaaaa tttaattgaa agctttgtgt tacgtgaagg caccgattat
     1801 ggtgaacatg agcgtacact tgaacagaaa gtcgccgacg tcaaacgcca gctacagtgc
     1861 ggagaagcgg tgctggtatg gtcggagctg cacgaaacgg tcaatattat gccgcgcagt
     1921 cagtttcgcg aataacctgc aaccgtcggc ggacgagata ataatgatag ctaagtcatg
     1981 gagttactat gtctgccaaa catccggtca ttgcggtaac aggatccagc ggcgcgggga
     2041 ccaccaccac cagcctcgcg tttcgtaaaa tattcgcgca gttaaatctg catgcagctg
     2101 aggtggaagg cgacagtttt caccgttaca cccgcccgga aatggacatg gcgatccgca
     2161 aagcgcgcga cgccgggcgg catatcagct acttcggccc cgaggctaac gacttcggcc
     2221 tgctggaaca aaccttcatt gaatacggtc agagcggcaa agggaaatct cgcaaatatc
     2281 tgcataccta cgacgaagcc gtaccgtgga atcaggtacc ggggacattc accccctggc
     2341 aacctttacc ggaacccact gatgtactgt tttatgaagg tttacacggc ggcgtagtca
     2401 cgccacagca taacgttgcg cagcatgtgg acttactggt cggcgtggtg cctatcgtta
     2461 accttgagtg gattcaaaaa ctgatccgcg acaccagcga gcgcgggcac tcacgagaag
     2521 cagtgatgga ctcagtagtg cgttcaatgg aagactatat caactacatc acaccgcagt
     2581 tttcccgcac ccatcttaac ttccagcgcg ttcccaccgt cgacacttca aacccgttcg
     2641 cggcaaaagg tatcccgtcg ctcgatgaaa gctttgtggt gatccatttt cgtaatctgg
     2701 aagggatcga tttcccctgg ctgctggcga tgttgcaagg ctcattcatt tcccacatca
     2761 atacgttagt ggtaccgggc ggcaaaatgg gtctggcaat ggaattaatt atgctgccgc
     2821 tggtgcaacg attgatggaa ggaaagaaaa tcgagtaact ctgctattac gccggataaa
     2881 atactatccg gcttcacaac gggatagtta agtcacgcgg caaccacttc atacgagtga
     2941 gtaatattca ccgctttttc cagcatcaac gccactgaac aatatttctc ggcagagaga
     3001 tcaaccgcac gcgcaaccgc tgcgtctttc aggtcgcgac cggtgacgat aaaatgcaga
     3061 ttaatgtgcg taaacaggcg tggtgcctct tcgcggcgtt cagaggtcaa ttttacttca
     3121 caatcgacca catcctgacg ccctttttgc aggatcgaaa ccacatcgat ggcactgcaa
     3181 ccacccgccg ccatcaacac catttccatc ggacttggtg ctttatcgcc tgagttgccg
     3241 tccattaaaa tctgatgacc agaggcggat tcgcccagaa aagttaaccc ttcgacccac
     3301 ttcactcgcg cttgcatttt tgctactcca ctgcgtcaat tttcctgaca gagtacgcgt
     3361 actaaccaaa tcgcgcaacg gaaggcgacc tgggtcatgc tgaagcgaga caccaggaga
     3421 cacaaagcga aagctatgct aaaacagtca ggatgctaca gtaatacatt gatgtactgc
     3481 atgtatgcaa aggacgtcac attaccgtgc agtacagttg atagcccctt cccaggtagc
     3541 gggaagcata tttcggcaat ccagagacag cggcgttatc tggctctgga gaaagcttat
     3601 aacagaggat aaccgcgcat ggtgcttggc aaaacgcaaa cagacccgac tctcgaatgg
     3661 ttcttgtctc attgccacat tcataagtac ccatccaaga gcacgcttat tcaccagggt
     3721 gaaaaagcgg aaacgctgta ctacatcgtt aaaggctctg tggcagtgct gatcaaagac
     3781 gaagagggta aagaaatgat cctctcctat ctgaatcagg gtgattttat tggcgaactg
     3841 ggcctgtttg aagagggcca ggaacgtagc gcatgggtac gtgcgaaaac cgcctgtgaa
     3901 gtggctgaaa tttcgtacaa aaaatttcgc caattgattc aggtaaaccc ggacattctg
     3961 atgcgtttgt ctgcacagat ggcgcgtcgt ctgcaagtca cttcagagaa agtgggcaac
     4021 ctggcgttcc tcgacgtgac gggccgcatt gcacagactc tgctgaatct ggcaaaacaa
     4081 ccagacgcta tgactcaccc ggacggtatg caaatcaaaa ttacccgtca ggaaattggt
     4141 cagattgtcg gctgttctcg tgaaaccgtg ggacgcattc tgaagatgct ggaagatcag
     4201 aacctgatct ccgcacacgg taaaaccatc gtcgtttacg gcactcgtta atcccgtcgg
     4261 agtggcgcgt tacctggtag cgcgccattt tgtttccccc gatgtggcgc agactgattt
     4321 atcaccccga tatcaactat gcacttcgac aaacgctggt gctatgtttg cccgtggccg
     4381 ttgggttaat gcttggcgaa ttacgattcg gtctgctctt ctccctcgtt cctgcctgtt
     4441 gcaatattgc gggccttgat acgcctcata aacgtttttt caaacgctta atcattggtg
     4501 cgtcgctgtt tgccacctgt agcttgctga cacagctact actggcaaaa gatgttcccc
     4561 tgcccttttt gctgaccgga ttaacgctgg tacttggcgt cactgctgag ctggggccat
     4621 tgcacgcaaa attgcttcct gcatcgctgc tcgccgccat ttttaccctc agtttggcgg
     4681 gatacatgcc ggtctgggaa ccgttgctca tctatgcgtt gggcactctc tggtacggat
     4741 tgtttaactg gttttggttc tggatctggc gcgaacaacc gctgcgcgag tcactaagtc
     4801 tgctgtaccg tgaactggca gattattgtg aagccaaata cagcctgctt acccagcaca
     4861 ccgaccctga aaaagcgctg ccgccgctgc tggtgcgcca gcaaaaagcg gtcgatctaa
     4921 ttacccagtg ctatcagcaa atgcatatgc tttccgcgca aaataatact gactacaagc
     4981 ggatgctgcg tattttccag gaggcgctgg atttacagga acatatttcg gtcagtttgc
     5041 atcagccgga agaggtgcaa aagctggtcg agcgtagcca tgcggaagaa gttatccgct
     5101 ggaatgcgca aaccgtcgcc gctcgcctgc gcgtgctggc tgatgacatt ctttaccatc
     5161 gcctgccaac gcgttttacg atggaaaagc aaattggcgc actggaaaaa atcgcccgcc
     5221 agcatccgga taatccggtt gggcaattct gctactggca tttcagccgc atcgcccgcg
     5281 tgctgcgcac ccaaaaaccg ctctatgccc gtgacttact ggccgataaa cagcggcgaa
     5341 tgccattact tccggcgctg aaaagttatc tgtcactaaa gtctccggcg ctacgcaatg
     5401 ccggacgact cagtgtgatg ttaagcgttg ccagcctgat gggcaccgcg ctgcatctgc
     5461 cgaagtcgta ctggatcctg atgacggtat tgctggtgac acaaaatggc tatggcgcaa
     5521 cccgtctgag gattgtgaat cgctccgtgg gaaccgtggt cgggttaatc attgcgggcg
     5581 tggcgctgca ctttaaaatt cccgaaggtt acaccctgac gttgatgctg attaccaccc
     5641 tcgccagcta cctgatattg cgcaaaaact acggctgggc gacggtcggt tttactatta
     5701 ccgcagtgta taccctgcaa ctattgtggt tgaacggcga gcaatacatc cttccgcgtc
     5761 ttatcgatac cattattggt tgtttaattg ctttcggcgg tactgtctgg ctgtggccgc
     5821 agtggcagag cgggttattg cgtaaaaacg cccatgatgc tttagaagcc tatcaggaag
     5881 cgattcgctt gattcttagc gaggatccgc aacctacgcc actggcctgg cagcgaatgc
     5941 gggtaaatca ggcacataac actctgtata actcattgaa tcaggcgatg caggaaccgg
     6001 cgtttaacag ccattatctg gcagatatga aactgtgggt aacgcacagc cagtttattg
     6061 ttgagcatat taatgccatg accacgctgg cgcgggaaca ccgggcattg ccacctgaac
     6121 tggcacaaga gtatttacag tcttgtgaaa tcgccattca gcgttgtcag cagcgactgg
     6181 agtatgacga accgggtagt tctggcgatg ccaatatcat ggatgcgccg gagatgcagc
     6241 cgcacgaagg cgcggcaggt acgctggagc agcatttaca gcgggttatt ggtcatctga
     6301 acaccatgca caccatttcg tcgatggcat ggcgtcagcg accgcatcac gggatttggc
     6361 tgagtcgcaa gttgcgggat tcgaaggcgt aatgcaggct aaaccatcgg ataaggcatt
     6421 cacgccgcat ccgacatctt ttgcctgatg cttcgtattt acgccccaac caccttcgcc
     6481 accgcgtggg cgaaacgttg catcccttca tcgatatccg catcttccac caccagcgac
     6541 ggtgcaaaac gcatcacatc cggtccggca ttcagcacca ttacgccagc ctctgcgccc
     6601 gcatacagga aatcacgcgc ccgacctttg tactgtggtt tcagctctgc gccaatcaac
     6661 agccccatac cgcgaatatc gctaaataca tcgtactgct gatcgatctt ctgcagatgg
     6721 tcaacaaaac gctggcgttt cgcctgaatg ccttccagca cttcaggggt attgatgata
     6781 tcaaacgccg cccccgctac tgcacaggcc agaggattac cgccgtaggt ggaaccgtga
     6841 gaaccaggat gaaacgcaga agcaatttcc gccgtggtca gcatggcgct aatcgggaag
     6901 ccgccgccta acgctttcgc agaggtcaga atatccggcg taacgccgta gtgcatgtaa
     6961 gcaaacaaat cgccggtccg ccccatcccg cactgcactt catcaaacac caataatgcc
     7021 tgatgttgat cgcacagctc gcgcaagccc tgcaaaaact ctggcgtcgc tgccgtcaca
     7081 ccgccctcgc cctggatcgg ctcaaccacc accgcacagg tgtgatcatc catcaccgct
     7141 ttcactgcat ggagatcgtt aaagggaacg tggatgatgt ctgccggttt cggcccaaag
     7201 ccgtcggaat attttggctg cccacccacc gaaacggtaa acagcgagcg accatgaaaa
     7261 gcgttatgga aggcaataat tttggttttg aacgggctat gacgcacaca ggcgtaatgg
     7321 cgtgccagtt taaaggcggt ttcgttagct tccgtgccgg agttcataaa caccacgcgt
     7381 tcggcaaacg ttgcctcaat cagtttacgc ccaagacgca gcgccggttc attggtgaaa
     7441 acgttactga tatgccacag agtttcgccc tgggttttta acgcgttcac cagcgcagga
     7501 tggcaatggc ccaacgccgt aactgcaatg ccacccgcga aatcgacata ctccttgcct
     7561 tgctgatccc agattcggct gccctgacct tttaccggaa taaactctgc cggagcataa
     7621 atcggcagga tcacttcatc gaaagtcgcg cgtgtaattg ctgtttgttc aattgccatc
     7681 tcatgatcac cctgttacgc ataaacaaat gtgaaattat aaccacaaaa tatgcataaa
     7741 aaatcactaa atggcaatca gaaatcagcg atgcaggaaa ttagccagca gttgatgtcc
     7801 ttgttcgcta agaatacttt ctggatggaa ctgcacacct tccagatccc actggcgatg
     7861 gcgaatcccc ataatctcgc gggtttcgct ccaggccgtc acgtcaaagc acgctggtaa
     7921 tgagtcaggt tccaccacca gcgaatggta gcgtgtcacg gtaagtggat ttgccagccc
     7981 ccgaaatacg ccctcaccgt tatgtgtaat cggcgaggtt ttgccgtgca tgacctttgc
     8041 ggcgcgcaca actttaccgc caaatgcctg cgccattgcc tgatgaccga ggcagacgcc
     8101 aagaatcggc aagcgcccgg catagtggcg aataacgtca agggagatcc cggcttcatc
     8161 tggcgtacag gggccaggtg agatgacaat tttttgtggt ttaagggcgt cgatatccgc
     8221 cagcgtcaac gcatcgttgc gcttaaccag cacatccgcc cccagttcac aaaagtactg
     8281 gtagaggttc caggtaaaag aatcgtagtt atctataagc aggatcatgg cggctccggt
     8341 acaaaagaac cgcgctattt tactcagatt ccccggcttc gcttaccact ttgctaaata
     8401 tcatctgcag tgcggtgaga tcccccattg ccccactctg atttgcctga ttccaggcct
     8461 ctttttcgat accctgccag ctcagttgat atccggcatg aatcgccagt tgctcgaaga
     8521 agatccgctg tgccagacca cttcccaccc ggaagggatg cagcacgttg atttcacaat
     8581 agtaatgcgc cagccgctcg acgaacttcg ctttctccag gccaaccaga taaccttctt
     8641 cctccagatc ctgcatcagg gcattgccct ctttttcgat ataagcaaag tggcagaacg
     8701 gcgtatcacc ctgataaata tcaacttcac gcagttgccc tgcccagtcg aaaatatcct
     8761 gatacagctg gcgatggata gttcgcaaat gcggtaaacc gcgcaccagc ggaccaagct
     8821 caatggtcgc agcacgcagc gccgtcattt cgtaagcggc ctgttccagc cgctgctgct
     8881 ggcggatgtt cagccggtta cgcatgatat caaggcctgg ataaagatac ggatcgcgcc
     8941 cttcgccgaa tttatcgctc atagtgactc ctcagctctt caaggcgcgc taaagcctct
     9001 gcggcagtaa gagtgactaa aggcatctcg acgccttcaa gacggcgact ggcctgaaaa
     9061 ttacgattac gctgaagctc ccagagacgg gacttttgct tatcggtgag tttcttcact
     9121 tgatgcctcc ctgaacgtgt ccatttgcca caagtataag cggcaaatcc gggttacgcc
     9181 gggagagcag aagcgcgggc aagattgccc gcgcgagaaa tcattacggc aggactttag
     9241 cggaaaggat aactaccggt tttgacggca cattctggta cggaccaacg tcatgagtcg
     9301 gcacctggga aatcttatcg gcaacgtcca tgcctttcac cactttacca aataccgcgt
     9361 aaccgaaatc acgctgacca tggtcaagga aggcgttatc ggcaacgttg ataaagaact
     9421 ggctggtggc gctgtctttg tcagcggtac gtgccatcgc gatggtgcca cgcgtgttgc
     9481 gcaggccgtt atcggcttca tttttgattg gcgggtttgg ttttttctgc tgcatctgct
     9541 cggtgaaacc gccgccctga atcataaagc caggaatgac gcggtgaaag gtagtgttgt
     9601 tataaaaacc gctgttcaca taatcgacaa agttttgcac agacactggc gctttttgtt
     9661 tatccagctc cagttcgatg ttaccagctg aggttgtcaa caatacgtgc gggtcccctt
     9721 tcgctgccat tgctgcggga gaaagagcag aaagagcgaa aacagcagcc atcgccgcca
     9781 gggtcgattt gaacatgaga tttccttaac aaacagagca gaaaaaaagc aagtgaagag
     9841 attctaaata gccttcaaga acaaggccat ccctttacct aattttacgt atctgaaata
     9901 tatgtaacct gacgatcact ttttattccg tgatcaaaat cacctcttaa aatgcaattt
     9961 agcaaccgat tgcaataaaa catttaaaca gatcacaaaa tcacctaaaa tcgcccgctc
    10021 gcggcatatc ccgctatgcc attttatttt tgaacgcagg ccaatcatga ctaacagcaa
    10081 tcgcatcaag ctcacatgga ttagctttct ctcctacgca ctgactggtg cgttggttat
    10141 tgtcaccggg atggtgatgg gaaatatcgc cgattatttc aatctgcctg tttccagtat
    10201 gagtaatacc ttcaccttcc tcaacgccgg cattttaatc tctatcttcc tcaacgcctg
    10261 gctgatggaa atcgtcccgt tgaaaacgca gttacgtttt ggctttctcc tgatggtgct
    10321 ggcggttgcc ggtttgatgt tcagccacag cctggcgctg ttctcggcgg cgatgttcat
    10381 tctcggggtg gtcagcggca tcaccatgtc gattggtaca ttcctggtaa cacaaatgta
    10441 tgaagggcgt cagcgcggtt cccgcctgtt atttaccgac tccttcttca gtatggctgg
    10501 gatgattttc ccaatgatcg ccgcgtttct actggcgcgc agcattgagt ggtactgggt
    10561 ttatgcctgc atcgggctgg tgtatgtcgc tatttttatt ctgaccttcg gctgtgagtt
    10621 cccggcgctg ggcaaacatg cgccaaaaac ggatgctccg gtagagaaag aaaagtgggg
    10681 gatcggcgta ctgtttctct ctgttgcggc gttgtgctac atcctcggtc agttaggttt
    10741 tatctcctgg gtgcctgagt atgccaaagg cctgggcatg agcctgaacg acgcgggcac
    10801 gctggtgagt aacttctgga tgtcatacat ggtcggcatg tgggcgttca gctttattct
    10861 tcgcttcttt gatttgcaac gcattctgac cgtactggct ggtctggctg cgattctgat
    10921 gtacgtcttt aacaccggaa caccagcaca tatggcgtgg tcaattctcg ctctgggctt
    10981 cttctccagc gcgatctata ccaccatcat caccctgggt tcacagcaga ccaaagtacc
    11041 gtcgccaaaa ctggttaact ttgtcctgac ctgcggaacc atcggtacta tgttgacctt
    11101 tgtggttacc ggcccgatcg ttgaacatag cggtccgcag gcggcactgc ttacagcaaa
    11161 cggtctgtac gctgtcgtct ttgtgatgtg cttcctgtta ggtttcgtca gccgtcaccg
    11221 tcagcataac accctgacct ctcattaatt gctcatgccg gacggcacta tcgtcgtccg
    11281 gccttttcct ctcttccccc gctacgtgca tctatttcta taaacccgct cattttgtct
    11341 attttttgca caaacatgaa atatcagaca attccgtgac ttaagaaaat ttatacaaat
    11401 cagcaatata cccattaagg agtatataaa ggtgaatttg atttacatca ataagcgggg
    11461 ttgctgaatc gttaaggtag gcggtaatag aaaagaaatc gaggcaaaaa tgagcaaagt
    11521 cagactcgca attatcggta acggtatggt cggccatcgc tttatcgaag atcttcttga
    11581 taaatctgat gcggccaact ttgatattac cgttttctgt gaagaaccgc gcatcgctta
    11641 tgaccgcgta cacctctcgt cttacttctc tcaccacacc gccgaagagc tgtcgctggt
    11701 gcgcgaaggc ttctacgaga aacacggcat caaagttctg gtcggcgaac gcgctatcac
    11761 catcaaccgt caggagaagg tgattcactc cagcgccgga cgtaccgttt tttatgacaa
    11821 gctgatcatg gcaaccggtt cctacccgtg gatcccgcca atcaaaggtt ctgatactca
    11881 ggactgcttt gtctatcgca ctattgaaga cctcaacgcc attgaatcct gcgcccgtcg
    11941 cagcaaacgc ggtgccgttg ttggtggcgg cctgttaggt ctggaagccg caggcgcgct
    12001 gaaaaactta ggtattgaaa cccacgttat cgaatttgcc cctatgctga tggcagaaca
    12061 gcttgatcag atgggcggcg agcagctgcg tcgcaaaatc gaaagtatgg gcgtgcgcgt
    12121 tcacaccagc aaaaacaccc ttgagattgt gcaggaaggt gttgaagcgc gtaaaaccat
    12181 gcgttttgcc gacggcagcg aactggaagt cgactttatc gtcttctcta ccggtatccg
    12241 tccgcgcgat aagctggcaa cccagtgtgg tctggacgtt gctccgcgtg ggggtattgt
    12301 cattaatgat tcctgccaga cttccgatcc ggatatctac gccatcggtg aatgcgcaag
    12361 ctggaacaac cgtgtatttg gtctggtagc acctggctac aaaatggcgc aggtcgccgt
    12421 tgaccatatt ctcggtagcg aaaacgcctt tgaaggtgct gaccttagcg ccaagctgaa
    12481 actgctgggc gtagacgtag gcggtattgg tgatgcgcac ggtcgcacgc ctggcgcacg
    12541 tagctacgtt tacctcgacg aaagtaaaga gatctacaaa cgcctgattg tcagcgaaga
    12601 caacaaaacc ctgctcggtg cggtactggt gggcgatacc agcgactacg gtaacctgct
    12661 gcaactggtg ctgaacgcta tcgaactgcc ggaaaacccg gattccctga tcctgccagc
    12721 acactcgggt agcggcaagc cgtctatcgg tgttgataaa ctgccggaca gcgcgcaaat
    12781 ctgctcctgc ttcgacgtca ccaaaggtga tctgattgct gccatcaaca aaggctgcca
    12841 cacagttgcg gcgctgaaag ctgaaaccaa agcgggtact ggctgcggtg gctgtatccc
    12901 gctggtcact caggtactga acgcggaact ggcgaaacag ggcatcgaag ttaacaacaa
    12961 cctgtgcgaa cactttgctt attcgcgtca ggaactgttc catttgatcc gcgttgaagg
    13021 cattaaaacc ttcgaagaac tgctggcgaa acacggcaaa ggctacggtt gtgaagtttg
    13081 taaaccaacc gtcggttcgc tgctggcctc ctgctggaac gaatacattc tgaagccgga
    13141 acatactccg ctgcaggatt ctaacgacaa cttcctcgct aacatccaga aagacggcac
    13201 ctactcggtg atcccgcgtt ctccgggcgg tgaaatcacc ccggaagggc tgatggcggt
    13261 aggtcgtatc gcgcgtgaat ttaatctcta caccaagatc actggctccc agcgtctggc
    13321 gatgtttggc gcacagaaag acgatctgcc ggagatctgg cgtcagctga ttgaagccgg
    13381 cttcgaaacc ggtcatgcct atgcgaaagc actgcgtatg gcgaaaacct gcgtgggtag
    13441 cacctggtgc cgctacggcg ttggcgacag cgtcggcctc ggcgtggaac tggaaaaccg
    13501 ctacaaaggc atccgtacgc cgcacaaaat gaagttcggt gtctccggct gtacccgtga
    13561 atgttcagaa gctcagggta aagacgtggg tattatcgcc actgaaaaag gctggaacct
    13621 gtatgtttgc ggtaacggcg gcatgaaacc gcgtcatgcg gatctgctgg cggcggatat
    13681 cgatcgcgaa acgctgatca aatatctcga ccgcttcatg atgttctaca tccgtactgc
    13741 cgacaaactg acgcgtaccg caccgtggtt agaaaacctc gaaggcggca tcgattacct
    13801 gaaagcagtg atcattgacg acaaactggg gctgaacgca catctggaag aagagatggc
    13861 gcgcctgcgt gaagcggtac tgtgtgagtg gactgaaacg gtcaatacgc cgtctgcgca
    13921 gactcgcttc aaacacttca tcaacagcga caagcgtgac ccgaacgtgc agatggtgcc
    13981 agagcgcgaa cagcaccgtc cggcaacgcc gtatgaacgt atcccagtaa ctctggtgga
    14041 ggacaacgca tgagccagtg gaaagacatc tgcaaaatcg atgacatcct gcctgaaacc
    14101 ggcgtctgcg cgctgttagg tgacgagcag gtcgcgattt tccgcccgta tcacagcgat
    14161 caggtgtttg cgatcagcaa catcgacccg ttcttcgagt ccagcgtgct gtcacgcgga
    14221 ctgattgcgg aacaccaggg cgagctgtgg gtcgccagcc cgctgaaaaa acagcgtttt
    14281 cgcttaagcg acggcttgtg catggaagac gaacagtttt ccgtcaaaca ttacgaagcg
    14341 cgagtgaaag acggcgtggt gcagctgcgc ggttaatgtt ttaacgggag gcgcaatgcc
    14401 tccccttttt gcatggtcct gtaataatct tcggtatatt gcaggacatt ttttaaactt
    14461 tttgttttat tttttgtttt tattttttaa aggataatca aatgtttaca gacactatta
    14521 ataagtgtgc ggctaacgct gcgcgcattg cacgcctgtc ggcaaataac ccgctcggct
    14581 tttgggtcag ctccgccatg gcgggcgcgt atgtgggtct tgggatcatc ctgattttca
    14641 cgctcggtaa tttgctcgat ccatccgtac gccctttggt gatgggcgcg acctttggta
    14701 tcgccttaac gctggtgatt atcgccggtt ctgaactgtt caccggacac accatgttcc
    14761 tcacctttgg ggtaaaagcg ggcagcatca gccacgggca aatgtgggca atcctgccgc
    14821 aaacctggct gggtaacctg gtcggttccg tcttcgttgc catgctctat agctggggcg
    14881 gcggtagcct gctgccggta gataccagca tcgttcactc cgtcgcgctg gctaaaacca
    14941 ctgcaccggc aatggtactc ttcttcaaag gtgcattgtg taactggctg gtttgcctgg
    15001 caatctggat ggcgctgcgc actgaagggg cggcgaaatt tatcgctatc tggtggtgtc
    15061 tgctggcatt tatcgcgtcc ggctacgagc actctatcgc taacatgacg ctgttcgcgc
    15121 tctcctggtt cggcaaccac agcgaagcct acacgctggc gggtattggt cataacctgc
    15181 tgtgggtgac gctgggtaat actttatcag gtgccgtatt catgggattg ggttattggt
    15241 atgctacgcc gaaagcgaat cgtccggttg cggacaaatt taatcaaact gaaacggctg
    15301 ccggttaatt actaaggggt ttttacgtgg atcatttgcc tatattttgc caattacgcg
    15361 atcgcgactg tctgattgtc ggcggtggtg atgtcgcgga acgcaaagca aggttgctgt
    15421 tagacgcagg cgctcgctta acggtgaatg cattagcgtt tattccacag ttcaccgcat
    15481 gggcagatgc aggcatgtta accctcgtcg aagggccatt tgatgaaagc cttctcgaca
    15541 cctgctggct ggcgattgca gcgacggatg atgacgcgct taaccagcgc gtcagcgaag
    15601 ccgctgaagc tcgtcgcatc ttctgtaacg tggtcgatgc gccgaaagcc gccagcttta
    15661 ttatgccgtc gattattgac cgctcaccgc tcatggtagc ggtctcctct ggcggcacct
    15721 ctccggttct ggcacgcctg ttgcgcgaaa aacttgaatc actgctgccg ttacatctgg
    15781 gccaggtagc gaaatacgcc gggcaattac gcgggcgagt gaaacaacag ttcgccacga
    15841 tgggtgagcg tcgccgtttc tgggagaaat tgttcgttaa cgaccgcctg gcgcagtcgc
    15901 tggcaaacaa cgatcagaaa gccattactg aaacgaccga acagttaatc aacgaaccgc
    15961 tcgaccatcg cggtgaagtg gtgctggttg gtgcaggtcc gggcgatgcc gggctgctga
    16021 cactgaaagg actgcaacaa attcagcagg cagatgtggt ggtctacgac cgtctggttt
    16081 ctgacgatat tatgaatctg gtacgccgcg atgcggaccg tgttttcgtc ggcaaacgcg
    16141 cgggatacca ctgcgtaccc caggaagaga ttaaccagat cctgctgcgg gaagcgcaaa
    16201 aaggcaaacg cgtggtgcgg ctgaaaggtg gcgatccgtt tatttttggc cgtggtggcg
    16261 aagagctgga aacactgtgc aacgcgggta ttccgttctc ggtggttccg ggtattaccg
    16321 cagcttctgg ttgctctgcc tattcgggta ttccactcac gcatcgcgat tatgcccaga
    16381 gcgtacgctt aattaccgga cacttaaaaa ccggtggcga gctggactgg gaaaacctgg
    16441 cggcagaaaa acagacgctg gtgttctata tggggttgaa tcaggccgcg actattcagc
    16501 aaaagctgat tgaacacgga atgccaggcg aaatgccggt ggcaattgtc gaaaacggta
    16561 cggcagtcac gcagcgcgtg attgacggta cgctcacaca gctgggagaa ctggcgcagc
    16621 aaatgaacag tccatcgcta attattattg gtcgggttgt tggcctgcgc gataaactga
    16681 actggttctc caaccattaa tttaacccgg gccagagaat tctggccttc ttaatgactc
    16741 tttttatata ttcagcaaat aaaacatagc cccttaataa atattatctg ctaatgggtt
    16801 atattcaccg ttacagcgac ttacaaaatt aagtcattcg ctcactgacg ccaattaaat
    16861 attcctgtat cgttcttaac gagcagtctg cttatattca tataatcaat gaatattaat
    16921 taatatataa tacataggga atgtaaatga acaaatttat taaagttgca ctggtaggtg
    16981 cagtactggc tacgttaact gcatgtactg gtcatattga aaaccgtgat aagaactgct
    17041 cttacgacta cctgctgcac ccggcaattt ctatttctaa aatcattggc ggttgcggtc
    17101 ctactgcaca gtaagtctct gacagaaatc ggctaacacc ggtttaattg cccgacgccc
    17161 tctggatttt ccgagggcgt atttgtttct atgtccttct tgcccccgcc cgtaaaaata
    17221 ttttcacttt aaattcaatt tgataactac atccattagc cacagcgcga tcctgtgcga
    17281 aattttgtga tcttcctcca cattacataa catcatatgt tgttatattc atcatgcatt
    17341 gtcatgttac cttttaaatg actgcaaact ctcccctaca acgtattgga caagaaaaag
    17401 gtatcgctat gggaagccag gaactccaac gcaagctcgg attttgggcc gttcttgcaa
    17461 tcgccgtcgg gacaaccgtc ggctccggta tttttgtatc tgtgggtgaa gtggcaaaag
    17521 cagcgggcac gccgtggctt acggtgctcg cgtttgtcat tggcgggtta attgtgatcc
    17581 cgcaaatgtg cgtctatgcg gaactatcca ccgcttatcc ggaaaatggc gcagattatg
    17641 tttatctgaa aaatgccgga agccgaccgc tggctttcct ctccggctgg gccagcttct
    17701 gggacaacga tgcgccgtca ttgtcgatta tggcgctggc gattgtcagc aatcttggct
    17761 ttttaacgcc tatcgatccg ttgctcggta aatttatcgc cgccggatta attatcgcct
    17821 ttatgttgct acacctgcgc tccgttgaag gcggcgcagc gtttcggacg ctaattacca
    17881 tcgccaaaat tatcccgttc actatcgtca ttggccttgg gatcttctgg tttaaagcgg
    17941 agaattttgc cgcccctacc accactgcga ttggcgcaac gggcagcttt atggcgctgc
    18001 tggcggggat ctctgccacc agttggtcgt ataccggcat ggcctctatc tgttatatga
    18061 ccggcgaaat taaaaacccc ggaaaaacca tgccacgagc gctgattggt tcctgtctgc
    18121 tggttctggt gctctacacc ctgctggcgc tggtgatttc cggcctgatg cccttcgaca
    18181 aactcgccaa ttctgaaacg ccgatttccg acgccctgac ctggatcccc gcactcggca
    18241 gcaccgctgg gatctttgtt gccatcacgg cgatgatcgt cattcttggt tcgctttcca
    18301 gctgcgtgat gtaccagccg cggctggaat acgcgatggc gaaagacaac ctgttcttta
    18361 aatgcttcgg ccatgtgcat ccgaaataca acacgccgga tgtctccatc atcctgcaag
    18421 gggcgctggg gatcttcttc atcttcgttt ccgatctcac cagcctgctg ggttatttca
    18481 ccctggtgat gtgtttcaaa aataccctca ccttcggctc catcatctgg tgtcgtaaac
    18541 gcgacgatta caaaccgctg tggcgtactc cggctttcgg gctgatgacc accctcgcca
    18601 ttgcgtcaag cctcattctg gtcgcctcaa cctttgtctg ggcaccgatt cccggcctta
    18661 tctgcgccgt catcgttatt gctactggtc tgcctgctta cgccttctgg gcgaagcgta
    18721 gccgccagct caacgctttg tcgtaatgtt atctggagaa aataaaatgt tggatattga
    18781 taaaagcacc gtggactttc tggtcaccga aaatatggtt caggaagtgg aaaaagttct
    18841 cagccatgac gttccgctgg tgcacgccat cgtggaagag atggtgaagc gcgacattga
    18901 tcgtatttat ttcgttgcct gcggatcgcc actcaacgcg gcgcaaacgg cgaaacatct
    18961 ggcggatcgc ttttccgatc ttcaggtcta cgccatttcc ggctgggagt tctgcgataa
    19021 caccccgtat cgcctcgacg atcgttgcgc agtaattggc gtttctgact acggtaaaac
    19081 cgaagaggta atcaaagcgc tggagctggg ccgggcctgc ggcgcactca ctgcggcgtt
    19141 caccaaacgc gcggatagcc cgattacctc ggcggcggaa tttagcattg attatcaggc
    19201 cgactgtatc tgggaaattc acctgctgct ctgctacagc gtggtgctgg agatgatcac
    19261 ccgcctcgcg ccgaacgcgg aaatcggcaa gatcaaaaac gatctcaagc agttgccgaa
    19321 tgcgctcggt catctggtac gcacctggga agaaaaaggc cgccagcttg gtgaactggc
    19381 cagccagtgg ccgatgattt ataccgttgc tgcgggtccg ctgcgtccgc tgggttacaa
    19441 agaaggcatt gtaacgctga tggaatttac ctggacgcac ggctgcgtga ttgagagcgg
    19501 agagttccgc catggcccgc tggagattgt cgaaccgggc gttccgttcc tgttcctgct
    19561 cggcaatgat gaaagtcgcc acaccaccga acgcgccatt aactttgtta aacagcgtac
    19621 tgacaacgtg atcgtcatcg attacgccga aatttcgcaa gggctgcacc cgtggctggc
    19681 accgttcctg atgttcgtgc caatggagtg gctctgctac tacctgtcta tttacaaaga
    19741 tcacaacccg gatgaacgcc gctattacgg tggtctggtg gaatattaat ccctctcccg
    19801 gcccggcaac ggggcggatt tacgcaagga gttacccgat gaaaacaggt atgtttacct
    19861 gcggccacca gcggctgcct attgaacacg catttcgtga tgcaagcgag ctgggttacg
    19921 acggcatcga aatttggggc ggtcgcccgc acgcgttcgc gccggactta aaagcgggcg
    19981 gcatcaaaca aatcaaggcg ctggcgcaga cgtatcagat gccgattatc ggctatacgc
    20041 cagaaaccaa cggctatccg tataacatga tgctgggcga tgaacatatg cgtcgcgaaa
    20101 gcctcgacat gatcaagctg gcgatggata tggcaaaaga gatgaacgcg ggttatacgc
    20161 tgatttccgc ggcccacgcg ggctatctca cgccacctaa tgttatctgg ggacggctgg
    20221 cagagaacct aagcgaactg tgtgagtacg cggaaaacat cggcatggat ctaatcctcg
    20281 aaccgttaac gccgtatgaa tcgaacgtcg tgtgtaatgc taatgatgtg cttcatgcgc
    20341 tggcgctggt gccttcgccg cgcctgttca gcatggtcga catttgcgcg ccgtatgtcc
    20401 aggcggaacc ggtgatgagt tatttcgaca aactgggcga taaattacgt catctgcata
    20461 ttgtcgacag cgacggggcc agcgacacgc attacattcc tggagaaggc aaaatgccgc
    20521 tgcgggaact gatgcgcgat attattgagc ggggctatga gggttactgt acggtggagc
    20581 tggtgacgat gtatatgaac gagcccagac tctatgcccg ccaggcgctg gaacgctttc
    20641 gcgcgctgct gccggaggat gagagatgaa aaccctggcg acaatcggcg ataactgcgt
    20701 cgatatctac ccgcaactga ataaagcgtt ttctggcggt aatgcggtca atgtggcggt
    20761 gtactgcact cgctacggca tacagccggg atgcattacc tgggtgggtg acgatgacta
    20821 cggcacaaag ctgaagcagg atctcgcccg catgggcgtc gatatcagcc atgtccatac
    20881 gaaacacggc gttaccgcac aaactcaggt ggaactgcac gacaatgatc gcgtttttgg
    20941 cgactacacc gaaggcgtga tggccgactt tgccctgagt gaagaggatt acgcctggct
    21001 ggcgcagtat gacattgtgc acgcggcaat ctggggacat gcggaagacg cattcccaca
    21061 gctgcacgct gcgggcaaac ttaccgcttt cgacttctcc gacaagtggg acagcccgct
    21121 ctggcagaca ctggtgccgc atctcgattt tgcctttgcc tccgcaccgc aagaagacga
    21181 aacgctgcgt ctgaagatga aagcgattgt tgcccgtggc gcaggaacag tgattgtcac
    21241 gctgggtgaa aacggcagca ttgcctggga tggcgcgcag ttctggcgtc aggctcctga
    21301 accggtgacg gttatcgaca ccatgggtgc cggagattcg ttcattgccg gattcctttg
    21361 cggctggtct gcggggatga cattaccgca ggcgatagcg cagggaacgg cgtgcgcggc
    21421 gaaaaccatt cagtaccacg gtgcctggta ggtataacgt tggcgtgagc atcttcacgc
    21481 caacgtgctg ttacttgccg gaaaacgacc ctataatccg agtaattcat tctttatttc
    21541 agggtcgatt atgtcagcta cggaccgcta ctctcatcaa ctcctctacg ctaccgtccg
    21601 ccagcgactg ctggatgata tcgcgcaggg ggtttaccag gccgggcaac agatccctac
    21661 cgaaaacgag ctttgtacac aatataacgt cagccgcatt accattcgca aagccatcag
    21721 cgacttagtg gcagacggcg tactgatccg ctggcaggga aaaggcacct ttgtacaaag
    21781 ccagaaagtt gaaaacgccc tgcttactgt cagtggtttt accgattttg gcgtctcaca
    21841 aggcaaggcg acgaaagaga aagtgatcga acaggaacgg gtcagcgccg cgccgttttg
    21901 cgaaaagctg aacatccccg gaaacagcga agtgttccat ctctgccggg tgatgtatct
    21961 cgataaagag ccgctgttta ttgatagttc atggatcccg ctgtcgcgtt atcctgactt
    22021 tgatgagatt tacgtcgaag gaagctccac ctatcagtta tttcaggagc gttttgacac
    22081 gcgagtggtc agcgacaaaa agaccatcga tatctttgcc gccacccgcc cgcgggcaaa
    22141 atggctgaaa tgcgaactgg gcgaaccgtt gtttcgcatc agcaaaatcg cctttgatca
    22201 gaatgacaaa ccggtgcacg tctccgaact cttctgccgc gccaatcgca tcaccttaac
    22261 tattgataat aaaagacatt aaccgtaggc cggataagat gcgccagcat cgcatccggc
    22321 gatgctggcg cgttgaattt tacatcccgt acgttcccct caccctaacc ctctccccaa
    22381 aggggcgagg ggaccgttca gtacggaatt tagcttgacg gtgctatcca gcattaaata
    22441 ctggcaatac tctcacgcaa aatccgcagc accgtctctt caccgctgcg attcgggtta
    22501 atgcgaatcg cacaatgttc tgattgtgga ttcgcctggc gaaacgttcc ggaaaggcga
    22561 taaaagagcg gcgggatttc atatttcgac tctgcaccca ccgggtaagg caaggcaccg
    22621 cgcttttgcg cctcttccag cactctggcg gcaatcggct gatgaaactc gacaatcaac
    22681 accttcgact gcgcattagc aatcaccgcg cttttcactt ccggcaccgc accaccgtta
    22741 agcaaagcca gcaaccgttc agatacccct gcctgcaccg cgtgcatcac tggcgcaaac
    22801 accagaccac gcaatacttc cagcgcctgt gcgccctgga tctggctacc gctggagtaa
    22861 agcgtggcgc gaatacggtt gataacatca gcatcgccga ccactgcacc aacaccctct
    22921 ggcccaaata gcttgaagca ggaaaatgtc gagacattcg cgccgcattc acagccgatt
    22981 cgagccacct tcatcaccgc atagttgtca tcggttaacg ctggaacacc tgccgcgcgc
    23041 aacgttgcca gcacatctgc cagcacgtag ctgtcctgcg gctgctggcg cgtatgctgc
    23101 accagcgccg catccggttg ttgctcgtcg acgacctgct tcagtgccga caggtcattg
    23161 aaatcaacag taataagcgt cagccccatc tgctcaataa taacccgtgt cgtcgggtaa
    23221 acaggcgcgt catgcaccag aagacgctgc cccggtttga gcaaagccgc cagcccggcg
    23281 cgaatcgcgc cagtccccgc gccctgcacc agcgccgcag cctgtgcgtg aaatgcatca
    23341 gccagcacct gttccacacg ctgggtaacg cgcggttgat tcagtcctgg cgttaagcct
    23401 aaatcaccgc cagtaagaaa ctcgctgccg gggaaatggc gacaaatgct atccaccagc
    23461 gcaaactgct tttgctgcgc ctcaataatc gtcaggcttt gcagaggaaa cgtcttcata
    23521 ggtgccttcc ttaagccgga acgaacaggc caagccagta aagaacattc agcagaatac
    23581 cggtgatcat tactgccacg accggtgccg ccattttctg taccggacgg cccagggatt
    23641 cgttgaggaa gtaaatggca accgcgatag agaatccggt ataacccgcc atcttaattg
    23701 ctgcgaaaat cgaaccgacc agcagcgcca cttccatcag catattcatg gcgttacgga
    23761 tgttatccga cgcattacgc accgacgggt agcgtcccag ccatttgccg atcgaacgaa
    23821 gcagcaagac ttccgccgaa ataaccactg cgcctaatac cgctgcaacc atcggattcg
    23881 gcgagagata gcccaccgca taaacaaagg taaagcccgc aactgcatac acacccgttg
    23941 ctaacgcggt ggtggcaatc aacggcacaa accccagtcc gcgcataaat tctgccagag
    24001 ccgcctgatt aatcagcgtt tgcgattgtt ccggcgttac gcctgcggaa tatgctttct
    24061 ccagtgtgaa gatcgacact tcactgccag caaaaatctt catgctggca acggcggcaa
    24121 tcaatgctcc cacgatggcg atatagggta agtttttgat aatccgtgac gtgcgttctt
    24181 caaacaccga aagcccgctg gcatcaatgt cattttcatc acgatgacgc aggtcgtgag
    24241 ttatcgcgat ccccagcagc atcaccatgc caataaagat ttcgatggat tcagggttaa
    24301 gatgtgggaa atagcgcacg actaccacac gggtcatcag taccaccacg gcggcgatca
    24361 gactttgctt ccagccaaac tggtagaaaa tcgccaccag cgggaacagt gcaaaagctg
    24421 aaaccaccgg cgagcttaat tcccccaggc tacctaatac atccaccggc agcgcggtca
    24481 gcagctggtt tactggcaac aggcaagtaa ggatcaacac gccccagata gcgccaagac
    24541 caaacgccat caggctgttt atcgccagga cgccgaggat atcggtagga agaaagagta
    24601 accatgcgtt gagcagcccg gttttcaggg taaaagagat ccccaccgag gccacaaaac
    24661 caatgctcag accaaaagcg atactccccg cctcgcgacg gttcatatag ccttcaatca
    24721 gttgcggcag gatcgggcgg atgccgtcat gaaaaacagc cgccgagcga tgcgccagaa
    24781 gcgatgtcat acccgtcagg cacgccacca cgataatctg aatatacaga tccatagtcg
    24841 tgccttttat ttcagatggt taatcagcat cggaatcgcg tgttcgacgt gctcaacgga
    24901 aaggccaaac gccacttttc cttcagcgat cattttggcg atatgctcgt ctttcgcttt
    24961 aatgcctggt ttggcaatgg tgcaactttt gttatagcct atcaccgcga tggcaatcga
    25021 caatgccgcg cccgcaccgg tattacacgc gccgatgtaa taatccagtt gcccggattt
    25081 caccttcatt gccgcttcca tgtcgttgtg aatgaaaact tcaaaacagc caggagccgt
    25141 cgcttcaata gtttttttaa tctgctcacg ctgtaagcct gcaacgccaa tctttttcat
    25201 gagtctgtcc ttattggaaa aattgagagg gattttcacg taacatcaca tccacatcgg
    25261 cctgactgaa tcctgactgg cgcaattgcg gaataaaggt ggttagtaaa tagtcatagc
    25321 cataaccacc gttggctttt aaatgggagc ggcgcgtaat atccatcgac agcatgacgc
    25381 ggttcagcaa cccacggtcg cgtagcgcat gaagcatcgc aatacgcttt tcgtccgggt
    25441 agtaactgtt cttgccgatg gtgtcgaact gcacgtacgc gccgagatcg atcatcttca
    25501 aaatgttgtc gaggttgtct ttcagatcgc agtgaccaac ggtgacgcgc gaaagatcaa
    25561 ccccgtgggc ttgtagcaac gccagttgct ccagccccat cgtgctgaac gacgtatgcg
    25621 tggagatcgg gcgtccggtc tggttatgcg ccagcgcagc ggcaataaat accttctctt
    25681 ccagcggcgt aatctttcct tcgctggtgc cgatctccgc gatgatcccg gctttcagct
    25741 ccgtgccatc gataccctgt tcaatttcat cgaccatctc ctgcgccagt tcctgcacgc
    25801 tgcgggtcgc cacatgttcc gggaaaaacg cgtcctggta ataaccggta caggccacca
    25861 cgttgatccc cgtctcgcgc attacatcaa gcataaattg cgcattgcgc cccatgtaac
    25921 ggttggtcat ctcaatcaca ttacgcacgc cccgggtcat caggtcgttc atctcctggc
    25981 aaatgaacgc atactgatca aggcggcagt ccacgttgtt tttaaagccg gagagatcaa
    26041 tatgcagatg ctcatgggcg agggtgtaac ccgtcggatc aaaactcata gggtgtctcc
    26101 tgcaaaccgg agggaggaaa gaaaagagcg accattttgt ggcggtggcg cgcggaaaaa
    26161 ttcacacacg gtagccccca catcagaaag cgtggtgcgc acaccgagct gcgtagcgat
    26221 catcccttgc tgataaacca gcactggcac cacttcgcgg gtatggtggc tgtgaccaat
    26281 ggtcggatcg ttgccgtgat ccgccatcac gaccaggcaa tcatctggct gcatcgcctc
    26341 aacaagccgg gcaaggttac ggtcaacgac ctgcaaacgt tcggcataac gtgcgacgtc
    26401 ttctgcatga ccagcgaggt cggtttcctg aatgttggtg caaataaacg ccgtcggatg
    26461 ggtgttaaat tcgttgaggg tgatatccat aatccgctgg ctatccacca gattttgcca
    26521 gctcacgcca taaggattgt tgacgatatc tgccacctta cccaccagca cggttggcac
    26581 gcctgcttca tacagttttt gtggcacctg cactttttca tcgacgccat agcccatatg
    26641 cacgacctgg aaaccgttgt cataagcgcc agaacgcggc gcattgatac caataaagcg
    26701 cccttctttg ctttctgcgg catcgagaat gcgttgactg tcggttaaca ggccaccaaa
    26761 tgtaatgacc cgaccgacct gtacctgctc acgcacgata cgaccaattt tgattgcgtc
    26821 gtcaaaagag atcacagaga gattggcggt aatgttatag acctggccta aatccgcctc
    26881 gagattatcg ccaatcgcaa ccgcctgatt gacccacaga aattgcagat catcgccacg
    26941 gcgctccacc tgccagccag cggaaactaa tgcctgctca acacggtcaa tcacatcgcg
    27001 aaaaggcatc cgcagcggcg gtaacgggcg cgtgcctaaa atttcctgat gccccataaa
    27061 ggtatcgcca ccttcatgtt gcagctctgc cacgccccag gttgcggaat ctgacggctg
    27121 catatcgcct ggcgcataac ccaatgcgtt gattagcccc agcttctcca gcgttggtag
    27181 ctgcaaatgc ggcaactggc tcaggatgtg accacatgta ttcgctcccg catcttgcgg
    27241 acgcaccagc gtgacatctt tcattgcccc tacgccaaag ctatcaatca ctaacaccac
    27301 aaatcgcgcc attacgcccc cagagagttt ccaagactgt cataacgacc gacgatttcc
    27361 ggttcgccac gatgaatacc ggacaccagc accacatcgc tacgggtgac aaaaatctgc
    27421 gtgcgaaaac agagcaccac tgcactgctt accggaaact cgcctgccag cggcagggtg
    27481 tagtcgatac tgctgtcatc cacagttttg agattggttt cagtaatctt ttgattttct
    27541 ggcgtaaaca ccaacgcatg ttgcgcatga ccacgacgat agtaaccgcc gccgtagcag
    27601 tagctgtcgc cacggaaatg atgggagatt tcacttaacc agagcatcgc gatacgttca
    27661 ggctgatcgc cctgctggtt tgccggaata gtgcccgtca gcgcatgacc gggttcggca
    27721 tgagtcacac cgtattgcgc cagtaatggc agcgaagtgc agctggtcgc tgaaggcgcg
    27781 ttcagttgct caagtgcaat accagatttc gccagttgat cccgtgcctg tatcagcgtg
    27841 tgaagattcg gtgtcggcaa aacttttccg acagcctcat cccaaagcag gcaagggaaa
    27901 tgggtaagtc cggctaaatg cagccctggc agattctgga tttcggcgac aatctccggc
    27961 aacaccttga gggcaaaacc gctctcctgg cccggataaa gaaaatcatc gtcgctataa
    28021 actttaagca gcacagactg gattcgcccg gccttcaccg ccgccgcaga aacttcccgc
    28081 gctttgtcga gagtaaacac ggtgatgacg tcggtgccct gttcaacggc gtcagcaacc
    28141 tgatgacaag ggatttgtac cagatgcccc tgatgcgcca caggcaaacc agcgcggcgc
    28201 atgactcgcg cctctttgta atccaccgcc acaatgccgc tgtagcctaa tgccagcaat
    28261 ttttccgcca gccacggatt acgaccaaac tgcttggtca tcagatacag ttcaatgccg
    28321 taaagccgcg ccgtctcaat cagccgctta ccgttttcca gtatctgatc cacgtcgatc
    28381 acccagctgt ccggggcgat cttgccctgc tgccacaggc ttagtgcggc ggaaatcagc
    28441 gccgggttct ggcgtttcaa tgcttctaca aacatcttgt tgcctcgttt ctgttccttg
    28501 aattaaatat tcattttttt gaatatttag gttgtgcgac gtggatttgt cgggagcttc
    28561 aaacctcttc gttagcagcc atccataatc cataaaggtt ggccagcaaa tagccttctt
    28621 cacacgggtt aacttccagt gcgaattcct tcaacaacac ctgatgcaat tgcacaacgg
    28681 cttgccagtg gctggattgc gccagttctg ccagcaactc gttatccagc ggctctattt
    28741 cttcaccacg gcgactgcgc atcagtgcac tcgccatatg tgtcatcgcc atcgttcctt
    28801 gctcactgcg caccggcaga tggcactctg tttccagtac gttgacgacc tgcatcatgc
    28861 ctttgcagat gtccttatca ataacgcctg cctcgcaaag caggttgagt ctggtttcca
    28921 tatcagatgc ctttcgttta ataactcggt tcctgttccc cactcactac ccgttgttga
    28981 tgggcgagca gggcgtgttt atctacaacg gcacgcagca gttgttgcat tgggtaatca
    29041 tcgactcgcg tcaggaccac ggcttcggtg gcctgtaaaa atcgcggatc gtctgtgagc
    29101 ggcgtcgcct ctaatcccag catggtcagt tcgttttccg ccaccacgtt ccagatcacc
    29161 gcatcgacat cgcctttaac aatgcgttgt aaactctcgt gataagagag atcgactcgt
    29221 tccacatcac taccgccaaa aaaaacatcg gtcatgattt tctgatccgc cgaacggtta
    29281 tccagcccca cgcgcttcac gtttgcggac tcgcctttac ggcaaatcaa ctggtgctcg
    29341 ccaacgtagg tgtgcggccc caactccagc gcgaggcata agcctttttg cgtgagataa
    29401 ctttccgccg ctagtcgcga aaccaccgcc atgtcataca cgccattaag cagacactcc
    29461 acgcgaatat ccgcgccacg catgtgcgca tagtaaaaag gaatgccatc aaactgggct
    29521 ttcaatccgc tcgccaggcc ttcgtacaaa cgggtatagg gcaagggcat tgcacatacc
    29581 acgttgttga tatccacatg agtcagcaat gctttgttat ccatctcgac cagataactg
    29641 ccattgcgcc cacggcgttc aatccgtatc gctccgcttg attccagcgt tttcaacgcg
    29701 gcctgcgtca ggccaacgga tgaacggcat tcatttgcca gctcatctat ggttttcaat
    29761 cgattaccgc acttttcacc caacaaataa cgggccagcg tcgtgatgac gacgccttct
    29821 tttttgataa acgttcgacg cataataaat tttcagtaaa ttgaatattt atatcttcag
    29881 gaatttgaag ataaggcgca acagcgagat gtggaaacgg cgaggcactt cacatttttt
    29941 cggattattg caaatgagga taaaaaaacc gggtttcccc ggtttcagag tgatgataaa
    30001 agcaaaattg cctgatgcgc tacgcttatc aggcctacat ttccttgcaa tatgtgcatt
    30061 actttgtagg ccggataagg cgttcacgcc gcatccggca tgaacaaagc gcaatttgcc
    30121 agcaatagtg aattacggct tcgccacaaa accaatcgct tcgtacaccg cttttagcgt
    30181 acgggaagcg tgcgcgctgg ctttttccgc gccatctttc atcacctgtt gcaggaaggc
    30241 ttcatcgttg cggaaacggt gatagcgttc ctgcaattca gtcagcatac cggaaacggc
    30301 atcagccact tcacctttca gatgaccata catcttgcct tcgaactgtt tttccagttc
    30361 tgggatgctc tggcccgtta ccgctgaaag gatatccaac aggttggaaa cgcccgcttt
    30421 gttctgcaca tcgtagcgaa ctaccggcgg ctcgtcggag tcagtgaccg cacgtttgat
    30481 tttcttcact accgatttcg gatcttccag caggccgata acgttattgc gattatcgtc
    30541 agacttggac atcttcttgg tcggctccag cagcgacatt acgcgcgcgc cagatttcgg
    30601 aataaacggc tccggcacct taaagatctc gccatacagc gcgttgaaac gctgggcaat
    30661 atcgcggctc agttcgaggt gctgtttctg gtcttcaccc accggtacca gattagtttg
    30721 atacagcagg atgtccgctg ccatcagcac cggatagtca aacagaccag cgttgatgtt
    30781 ctcggcataa cgcgcagatt tatctttaaa ctgcgtcatg cgactcagtt cgccgaagta
    30841 ggtatagcag ttcagtgccc agcctaactg tgcatgttcc ggcacgtggg actgaacaaa
    30901 aatggtgctt ttctcaggat cgataccaca agccagatac aaggccagcg tatccagcgt
    30961 cgctttacgc agcttctgtg catcctggcg cacggtgatc gcgtgttggt caacgataca
    31021 gtaaatgcaa tggtagtcat cctgcatgtt tacccactga cgcagcgcac ccatgtagtt
    31081 accaatggtc aattcacctg agggctgtgc gccactaaaa acgatgggct tagtcatttt
    31141 tcgattcctg attttcgcta tgcggaagcc ctaatgcggg cagaaggtca tttatagact
    31201 gataaattac atcaggctgg ctgagatcga tagcctcgcc gtagttatat ccgtaggtta
    31261 agccaactga tgggcaacct gccgcttttg ccgcctgaat atcattgcgt gagtcgccga
    31321 caaacagcat ctgttgtggg gcaattccca tccgctcagc caccagtaac agcgggtccg
    31381 gatgcggttt tttgttttgc acatcatcac caccaatcac cacgctgaag tatttggcga
    31441 tatctaaggc ttcgagcagc ggcgcgacga acggcgtcgg tttgttggtg accaggccta
    31501 gcggcaggcc tttagcctgc aacgcgccca acgtatcggc aacgtgcggg aacaaaaacg
    31561 tcccctcttc ggcaacctcg ccatagtagc gatcgaacag tttacgcaga atacgtacct
    31621 gttcttctgc cggaatgtcg tcatcaacgg gcggtttacc cattgtttta cgctgagtcg
    31681 cacgttcctg acgcgcccag gtcaatgcgc gctccatcag aacatctgcg ccgttaccaa
    31741 tccaggtaat aacgcgttct tcacctgcga cgggcaactc cagcgcatac agcgccatat
    31801 ctaccgcagc agcaagacca ggagcactgt cgaccagcgt accatcaaga tcaaaagcga
    31861 cgccgcgaat atcttcaaac ttattcatga cttacctttg ccagttcact gcgcatttca
    31921 tcaatgactt ttttgtagtc tggctggtcg aagattgccg aaccggcgac gaacatatcc
    31981 gcgcccgccg cagcgatttc gccaatgttg ttcaccttca cgccaccgtc cacttctagt
    32041 cgaatgtcaa agccagactc gtcgatacgg cgacgtactt cgcgcagttt atccagtgtt
    32101 tgaggaatga aagactgacc gccgaaacca gggttgacgg acatcagcag gatcacatcc
    32161 agcttatcca tcacgtaatc cagatagctc agaggtgtcg ccgggttaaa taccagaccc
    32221 gctttacagc cattttcttt aatcagttgc agcgtgcggt caacatgctc ggaggcttct
    32281 ggatgaaagg taatgatgct ggcaccagcg gcagcgaaat caggcacaat gcgatcgacg
    32341 ggtttcacca tcaggtgtac gtcgataggg gcggtaatgc catagttacg caaggatttc
    32401 agcaccattg gcccaatcgt cagattggga acatagtggt tatccatgac gtcaaaatgc
    32461 acgacatcag cgccagctgc cagggctttt gcggtatctt cacccaggcg ggcaaaatca
    32521 gccgacagaa ttgagggggc aatcaaatac tgtttcatcc gcttctcctt gagaattatt
    32581 ttttcgcggg tgaaacgact cctggtttgt acaaagccag cagttcgtcc acctttttac
    32641 gtgtgccgcc gttgctgctt atactgcgtc gaactttgac gacatgcaat tttgcgcgct
    32701 gataccactc acgcgttaac atcgtatcgt gattggagat cagcactgga atatggcgct
    32761 caaccagacc ttcggcgatc tccgccagat gcgcttgttg ttcaagcgta aaactgtttg
    32821 tgtgatacgc cgtaaagttg gcggtcgcag acagcggtgc ataaggcgga tcgcaataga
    32881 cgacggatgc atcatctgcg cgcgccatgc tatcggcgta agactcacaa tagaaaaagg
    32941 cattctgcgc tttttcagcg aagtgataca actctgcttc cgggaaatag ggttttttgt
    33001 agcggccgaa cggcacgtta aactcaccgc gcagattgta acgacacagg ccgttgtaac
    33061 cgtagcggtt caaatataaa aacagtaccg cccgacggaa cggatcctgg cttttgttga
    33121 actcttcgcg gaactgatag taaacctcgg cgcaatttgt ttcgggaaca aacagctcgc
    33181 gtgcggcctg tacgtactca tcagtacgca tcttcacaat gttatagaga ctgatcaggt
    33241 cgctattgat atcggcaagg atataacgag aaaagtcggt gttgagaaac accgacccgg
    33301 cacctacaaa aggctcaacc agacattcgc ccttgggcaa atgccgttta atatcatcaa
    33361 gcaggggata cttgccccct gcccacttca aaaaagcgcg atttttcttc atgctgacta
    33421 actaattaca ccttctccgg ctgtggagaa agctccgaca gcatccagcg cttcaggcaa
    33481 ctcccgcaac gataaaccat tgcgggagat aaccttgatt acttcagatc ggcctgtacc
    33541 tgacgcagcg gtttcgccca cgggtttttg gcctggacat ctgctggcaa tgtagatacc
    33601 gcttttttcg cctcttcttt cgaagcgtac acgccagaaa ccaggacata ccacggctga
    33661 ccattacgcg tcgtttcata gacaacgtag tttttcagat tctctttctt cgcccaaccg
    33721 ttcaggttgt cgtagttaga ggaactgctc agctgcagag tgtaatggct ggacggtgcc
    33781 gatttcaacg aaccaacatt acctgcggtc ttcgccccag cagcgggtgt tgctgtggtt
    33841 tgcgccgggg atgccgtctg tactggagcc gtagtcgccg tctcttttgg tgctggcgta
    33901 gaagtcgcag ccggtgcctt cgtgctcgcc acaggggcag ctggttcagt acgcttcggc
    33961 gtctgtgcta ccggcttcgg ctccgttttc acggttgctt gcggtttttt cggttcaatc
    34021 accgcctgct gacgagctgg gcgcgtagtg gacggacgtt cagcggtttg cgttttcgcc
    34081 gtgtcacgcg atgcattgcc attgcgaaca ggcgcaaccg ttgcgggttc agtcggcaac
    34141 gtggaattga ccgccacatt gttcagctgt tgctgatttt gtggctgggt cagcgcattg
    34201 ttcaggtcac cctgcacttc aacacgttgt tgaccatccg ttgccaccgg ggtttgccct
    34261 tgagtcggcg tagaagagat cggtggcaga gaaacatcct gctgagtatt ttccgcagac
    34321 gtggttcccg gcgctggctg cacgccattc gcctgatcgg tcgcattgcc agcaagatca
    34381 atactcttct cgccagacgc ggtttgatcg ctggaagtgg tcgagggggc ttttagcgca
    34441 gaaccgatac cgatgatcaa cagcagtaga accagaatgc cgacgcccat catcatatac
    34501 tgacgagaag cgggtttact ggctgctttt ttgcgcttac gcggacgacg ctctacgcgc
    34561 tcttcatcca cggtttcatc ttcggattcg tcaatttctt cttcgatttc cggttcctca
    34621 ttgcgctctt tttgcgcacg agtcggacgg cgatcgtcag tgtcatcaag ttcaatatca
    34681 tcaaaattga tctgcggttc gccacgttca gtacgctcag aacgttcaga agattgacga
    34741 gaacgaccag tacgacgatc gctgggatcg ggtttcagct cgtcttctgg tttgaattca
    34801 tccatttaac accccactaa aaggttaatg cttaccacgt tgcaattaac ctgaagctaa
    34861 tagaccgctt gataagcggc ctgacctttc ttgttgttac gctgattgac aatcggcaat
    34921 ggcgttaaga acaagctcgt gcgaaacgcc gctgcgaact tcactcttac caattgccaa
    34981 cggaagaatt aagcgcatct ctcccgcaag gactttcttg tcacgcagca tatgcggtaa
    35041 atacgcctgc gcggacattt cgcgcggccc attgaccggt aacccagccc gcttgagcag
    35101 ggttataata cgctgcgttt cggcagaact aaactgcccg agacgttccg acgtccgcgc
    35161 cgccatcacc atacccgcag cgaccgcttc accatgtaac caattgccat accccatttc
    35221 agcttcaatg gcatgaccaa aggtgtgtcc cagattcagt aaagcacgta acccggtttc
    35281 gcgctcgtcg gcggcgacaa cttctgcctt cagttcacaa caacggcgaa tacagtacgc
    35341 cattgccgga ccgtccagac gcaacaacgc atccagattc tcttccagcc agttaaaaaa
    35401 cgcaccgtca agaataatgc cgtatttgat gacttctgcc agccccgacg ctaactcacg
    35461 cgggggaagc gttttcagac agtcgagatc caccaccact gaagcaggtt ggtagaacgc
    35521 gccaatcatg tttttaccga ggggatggtt gaccgcagtt ttgccgccaa cggaggaatc
    35581 gacctgcgac agtaacgtcg tcgggacttg aatgaaacgg acaccgcgct gataactcgc
    35641 cgccgcgaag ccggtcagat cgcccactac gccgccgcca agcgccacca gcgtagtatc
    35701 gcgaccatgc ggtttttgta acaacgccgt aaagacggta tcgagtacag ccaggctttt
    35761 atactgctcg ccgtcaggga ggataacgct atcgacgtta acacccgcct gttcaagtac
    35821 gccgcggacc ttatcgagat acagaggagc cagggtttcg ttggtgacca acatgacctg
    35881 ctcgcccgat ttcagcggta agaatgaagc tggttcatta aacaaaccag atgcgatggt
    35941 aattgggtaa ctacgttccc cgagagtaac gacaatcctc tccataacgc gacatccacc
    36001 ttaattactg tacccgcaga cgagtgtata taaagccaga attagttgct ttccagcatg
    36061 tgaataatct ggtttgcaac cactttagcg ctttgatcat cagtacgaat ggtcacgtcg
    36121 gcaatctctt catacagcgg attgcgttca ttggccaacg cttccagaac ttcacgcggc
    36181 ggtgtttcaa cgtgcagcaa cgggcgtttt ttatcacgct gcgtgcgtgc aagttgcttt
    36241 tcgatggtcg tttcaagata aacgacaacg ccacgagcgg aaagacggtt acgcgtttca
    36301 cgggatttca cagagccgcc gccagtagcc agcacaatac cctgtttctc ggtcaactca
    36361 ttgatgacct tttcttcgcg atcgcggaag ccttcttcgc cttctaaatc gaaaacccag
    36421 cccacatcag ctccggttcg tttctcaatc tcttgatcgg aatcgtaaaa ttccatattg
    36481 agttgttgag ctaactggcg cccaatagtg ctttttccgg cacccatagg cccaaccaga
    36541 aagatattgc gtttctctgc cattttttcg gtactactaa gactattcgt taatgataaa
    36601 cccgcttcgc tcagagagcg ccgcaggaca tgaactgaaa cctcataaga tattgcgaga
    36661 gtcagactga aaattatctc aatactccag cgggtttggc aactgaataa atcacccatc
    36721 cctctgcata tctggtcgct gcaagcgcgc tgccttgcta ccaccgctct ggcgataaat
    36781 caccgggtaa gattagcgta aaaaagacag caaaatgccg cctgaatgat aaatcatcat
    36841 catggaacgc aggcagcgaa gagcaccaac tctcaaatcg gtactccttg tatgctaaat
    36901 acctgcgcgc gtcaaataga tgaaacacgt tcagcgtaaa aacattaccg cttttacggc
    36961 tgtttactca ctggaaacca gtcgtggcgt gataaacacc actaactcgc gtcgttcatc
    37021 ttcttttccg tcatgacgaa ataattgccc gaaccaggga atgtcgccaa gcaacggtac
    37081 gctatcctga cccgatttat ttttacgggt aaaaatgccg cccagcgcca acgtttctcc
    37141 gcttttgacc tcgacctgcg tttcgatctc ctgcttatca atcgccagca cttcgccatc
    37201 ggcctgctgt agcacctgcc ccggaacgtt ctggctgatg tgtaatttca gccggatgcg
    37261 acctttttgt aacaccgtgg gcgtgacctc catccccagg acggcctctt taaattccac
    37321 cgacgtcgcg ccactttccc cgctggaaac ctgatatgga atttcgctcc cctgtttaat
    37381 gctggcaggc tgaagatgtg aggccagcag acgcggactg gcgataatat ccagctgctg
    37441 tttttgttcg agcgcggaaa gctcaagatc cagcaagcgt ccgttgatgc gcccaatgtt
    37501 aaaaccgaca tgcgttgtcg ccgtcgctac ggagaggtcg ctaccaagcg tggtgacttg
    37561 cccaacgcca ccagcgtgtt gcgcatcggc cagcgtccat ttcacgccta actcacgcaa
    37621 acttttttca ttaatggtga caatatgcgc cgacagctca acctgcccga ccggcagatc
    37681 catttgcgct acccactgtt caagcgcgct taacgccgtt ttgttatctc gtagcaaaag
    37741 gcgattggtg cgtttatcga cggtcatact ccctttggca ctcagtagct tctcccccgc
    37801 tttcgccagt tctcccgcgt cggcgtattg cagggttata ctgcgatttt ccagcggcag
    37861 atttgcctgc gcccgcgcct gctccgcctc ctggcgggcg atattgttat tctgccaggc
    37921 aatggaatgc actgagagaa tgttgccttc ctgccgcgtt atcagtccgg cgcttttcac
    37981 tacagtttgt agtgcctgct tccagggaac atctgttaga tgtaacgaca ccgtaccgct
    38041 gacgtctggc gacacgacca ggttcaactt ctcctgttca gccagcgcct gcaacacctg
    38101 agctaccgga acgtcatcca ccatcagcgt cactttttgc ggctttgccg cctgtacgcc
    38161 gggtatcagc atcaacagta gtgcggctat ccattgcttc atttgtatct ccttgccgtt
    38221 gccacaacca ttgtggcggt tcgcagtttg tcccggtacc cagcgttagt acgtctggcg
    38281 tcagctgtaa aattgtccag ccgttttcca gcacatcgtt ttgctgcacc cgtcgccatt
    38341 tcttttgccc gtcttttatt acaccgatga tgcgctcgcc tcgccctacc atcccctgat
    38401 agcgccactg gctaagttcg ctaatccggc atagatcttc cggcggttta aaagggtcac
    38461 gcataccggt taaaaggcac aatgcaatac ctgccaacaa ccagcgttta accctcatgc
    38521 ggcgtctcca gttgtagcgt gaacaaaaga tcatcacctt ccacgcttaa cgaaaaacgg
    38581 ctcacgctga cgttgcgctc tgccagccgt gtaaatgccg acggcactgc ttcccacagc
    38641 gttttcaacg ccaactcgcc tccctgcgcg gatggatgcc aggaaaccag ttgcgcgccg
    38701 gataactgaa aatccagtgg cgaaaagggc agcgtttttt cctcgctgaa gggagtggtg
    38761 tctaccaggc gatacagtgc ggcccactgc tggtgatgac ttgcccgtag tcgaattaat
    38821 gcgtcgcgct cttcatggtg tgtcgatgac agaaaaatga gcgtaactaa catcagcaac
    38881 cagaatgccc agcaaagctg gcggaggcgg ggtgatgtgg cgaaccacca gtcaaagaac
    38941 atgttcatcg ctaaccttcc ttgttaactg atactcaaat tgccagcgtc cctgcgcatc
    39001 ctgctgcgtg gctccccgct gattgagatg aaaagatgca tcctggcgga gtgacgtttc
    39061 tagtgcgttt aacgcggtaa tgcttgttgt cagccccttg atctccagcg ttccctgctg
    39121 ccagcttatc gttgtcagcc aggcgtgctc gggtaaaagc gccgccagtg cttccagcgc
    39181 agattgccag tcgcgggtaa attgtcgctg gcgctgccgt tgcgaacgct gttcgcgtaa
    39241 ctgctgttgc tccagcaaac gtggcttcgt tatctgtaag ctgcgggcga gttgttgttc
    39301 cgcctgaagc aaaactgcgt ctatgcgcgc ttcggcgctg cctgtcagac gcagtattag
    39361 cgttatcccg acggccagca gcagaggcgc aacgaacatc agcaaccaga aacgcagaaa
    39421 agcggtccgg cgttgctgtc gccagggcaa aaaattaatt ggcgggttca tcagtacgcc
    39481 ttcccaagcg ccagccccag cgcgatggca aagtctccac ctggcggcgg tagcggcggc
    39541 tgacgaacag aaacggcctc ccagggatca aatccgcctt cgccacatat cgcgacgctt
    39601 tcgggatcaa cggataacgc tgccgccagc tccttcgcgc tagtcatccc caccgccagt
    39661 ttgcgccccc agctatagcg cgtcgcccac agccactgtt cgttatcacg ccaggccaga
    39721 cattgctgat gagaaggtaa aaaaggcagg aatcgctgta atgcactggc atccggggtg
    39781 atcgcgctca catgaacacg caacctttct gccagagtaa gcagcgttgc cagctctttg
    39841 ctttgcgcgg cagtcacgtt ataggcggga ctgagtgagt cttcgctgta atcgaagcgc
    39901 agggagtccg gatccatatc cagctcgcgg gccatcgtcc ctgacagcca ggccgtttgc
    39961 tcccgctcac caagggacat cgacgggcgc ggaaatgacc gctgtaatgt gcgactggcg
    40021 ggaaacgcca acataatgtg atgacgctgc ggcagttcgc gactccacgg taacaacgtt
    40081 ttagccagct gctgcgcatc aacaatccgc ccatctttga taatgtcgtt ctccagcggc
    40141 aaccgccacc agcgttgcaa aaagcattct tttgcgcccc gcacgatcgc aaccgctacc
    40201 gcttcttgct gttgtaaatg caaaccaatt tgccagatct taaatgccat tgtgatgatc
    40261 tccttatcac ccgtcactct gacgggtata tcaatgcgtc tggcttgcct ttatactacc
    40321 gcgcgtttgt ttataaactg cccaaatgaa actaaatggg aaatttccag tgaagttcgt
    40381 aaagtatttt ttgatccttg cagtctgttg cattctgctg ggagcaggct cgatttatgg
    40441 cctataccgc tacatcgagc cacaactgcc ggatgtggcg acattaaaag atgttcgcct
    40501 gcaaattccg atgcagattt acagcgccga tggcgagctg attgctcaat acggtgagaa
    40561 acgtcgtatt ccggttacgt tggatcaaat cccaccggag atggtgaaag cctttatcgc
    40621 gacagaagac agccgcttct acgagcatca cggcgttgac ccggtgggga tcttccgtgc
    40681 agcaagcgtg gcgctgttct ccggtcacgc gtcacaaggg gcaagtacca ttacccagca
    40741 gctggcgaga aacttcttcc tcagtccaga acgcacgctg atgcgtaaga ttaaggaagt
    40801 cttcctcgcg attcgcattg aacagctgct gacgaaagac gagatcctcg agctttatct
    40861 gaacaagatt taccttggtt accgcgccta tggtgtcggt gctgcggcac aagtctattt
    40921 cggaaaaacg gtcgaccaac tgacgctgaa cgaaatggcg gtgatagccg ggctgccgaa
    40981 agcgccttcc accttcaacc cgctctactc gatggatcgt gccgtcgcgc ggcgtaacgt
    41041 cgtgctgtcg cggatgctgg atgaagggta tatcacccaa caacagttcg atcagacacg
    41101 cactgaggcg attaacgcta actatcacgc gccggagatt gctttctctg cgccgtacct
    41161 gagcgaaatg gtgcgccagg agatgtataa ccgttatggc gaaagtgcct atgaagacgg
    41221 ttatcgcatt tacaccacca tcacccgcaa agtgcagcag gccgcgcagc aggcggtacg
    41281 taataacgtg ctggactacg acatgcgcca cggctatcgc ggcccggcaa atgtgctgtg
    41341 gaaagtgggc gagtcggcgt gggataacaa caagattacc gatacgctga aggcgctgcc
    41401 aacctatggt ccgctgctgc ctgccgcagt caccagcgcc aatcctcagc aagcgacggc
    41461 gatgctggcg gacgggtcga ccgtcgcatt gagtatggaa ggcgttcgct gggcgcgtcc
    41521 ttaccgttcg gatactcagc aaggaccgac gccgcgtaaa gtgaccgatg ttctgcaaac
    41581 gggtcagcaa atctgggttc gtcaggttgg cgatgcatgg tggctggcac aagtgccgga
    41641 agtgaactcg gcgctggtgt cgatcaatcc gcaaaacggt gccgttatgg cgctggtcgg
    41701 tggctttgat ttcaatcaga gcaagtttaa ccgcgccacc caggcactgc gtcaggtggg
    41761 ttccaacatc aaaccgttcc tctacaccgc ggcgatggat aaaggtctga cgctggcaag
    41821 tatgttgaac gatgtgccaa tttctcgctg ggatgcaagt gccggttctg actggcagcc
    41881 gaagaactca ccaccgcagt atgctggtcc aattcgctta cgtcaggggc tgggtcagtc
    41941 gaaaaacgtg gtgatggtac gcgcaatgcg ggcgatgggc gtcgactacg ctgcagaata
    42001 tctgcaacgc ttcggcttcc cggcacaaaa cattgtccac accgaatcgc tggcgctggg
    42061 ttcagcgtcc ttcaccccaa tgcaggtggc gcgcggctac gcggtcatgg cgaacggcgg
    42121 cttcctggtg gacccgtggt ttatcagcaa aattgaaaac gatcagggcg gcgtgatttt
    42181 cgaagcgaaa ccgaaagtag cctgcccgga atgcgatatt ccggtgattt acggtgatac
    42241 gcagaaatcg aacgtgctgg aaaataacga tgttgaagat gtcgctatct cccgcgagca
    42301 gcagaatgtt tctgtaccaa tgccgcagct ggagcaggca aatcaggcgt tagtggcgaa
    42361 gactggcgcg caggagtacg caccgcacgt catcaacact ccgctggcat tcctgattaa
    42421 gagtgctttg aacaccaata tctttggtga gccaggctgg cagggtactg gctggcgtgc
    42481 aggtcgtgat ttgcagcgtc gcgatatcgg cgggaaaacc gggaccacta acagttcgaa
    42541 agatgcgtgg ttctcgggtt acggtccggg cgttgtgacc tcggtctgga ttggctttga
    42601 tgatcaccgt cgtaatctcg gtcatacaac ggcttccgga gcgattaaag atcagatctc
    42661 aggttacgaa ggcggtgcca agagtgccca gcctgcatgg gacgcttata tgaaagccgt
    42721 tcttgaaggt gtgccggagc agccgctgac gccgccaccg ggtattgtga cggtgaatat
    42781 cgatcgcagc accgggcagt tagctaatgg tggcaacagc cgcgaagagt atttcatcga
    42841 aggtacgcag ccgacacaac aggcagtgca cgaggtggga acgaccatta tcgataatgg
    42901 cgaggcacag gaattgttct gattaaaaag gcgcttcggc gccttttcag tttgctgaca
    42961 aagtgcactt gtttatgccg gatacggcgt gaacgcgtta tccggctaac aaaatcgtga
    43021 aaactcaata aattgcagaa accccataag cctgataaac attgtgcatc aggcaaactt
    43081 cacgcattta cactcgcccc tgccctttca accattcgcg cacgaggaac agcgcactga
    43141 cattgcgcgc ttcattgaag tcagggtctt ccagcaaatc catcatatgc gccagcggcc
    43201 agcgcacctg tggtagcggc tctggctcat cgccttccag tgattccggg tagagatctt
    43261 gcgctaccac gatattcatt ttgctggaaa agtaagacgg tgccatgctg agcttcttca
    43321 aaaaagtcag atcgttcgct ccaaatccaa cctcttcttt tagctcgcgg ttagcggctt
    43381 cgtagacgct ttcacccgga tcaattaatc ctttcgaaaa acctaattcg taggattcag
    43441 ttcccactgc gtattcgcgg atcaggatca ggtgatcgtc cacaatcggc acaatcatca
    43501 ctgcttcccg gttggttgga cgcattcgtt cataaacacg ccgcacgcca ttgctgaact
    43561 ccagatccac gctctcgacg gtaaacagtc gggaacgggc tacagtttca acattcagaa
    43621 tggtgggttt ttgtaatgat ttgctcatcg tgggatctat gctgtgaaat cagcggttat
    43681 tgtgcgatat cggacacgct ttcggcaatg tgaattgcat gttatttaca tttatgtaac
    43741 ttaataaata atcgtcctca aatcaaatta aaagtcaata ggttgaaata actccaggaa
    43801 tttgctgata ttccgccttc agagggtttg ctatgatcag cggttactgt gatgtgctta
    43861 atgatgctca agttaaactc cacgcttgcc gatagccaac cgcagaatca tgtattgtgt
    43921 ccggtgcgac tgaccacgcc tgacagacta agtaagatgg ggaaagcatg agcaccattg
    43981 tgattttttt agctgctttg ctggcctgct cactacttgc gggatggctg ataaaagtgc
    44041 gatccagacg gcgtcagctg ccctggacca acgccttcgc ggatgcgcaa acgcgtaaac
    44101 tcacacctga agaacgtagc gccgttgaaa attatcttga gagcctgacg caggtattac
    44161 aggtgcctgg cccaacggga gccagcgcgg caccgatctc tctggcgctg aatgccgaaa
    44221 gcaacaacgt catgatgctg acacacgcta tcacgcgtta cggcatctct accgacgatc
    44281 cgaataaatg gcgttactac ctcgattcgg tagaagtcca cctgccccct ttctgggaac
    44341 agtacatcaa cgatgagaat accgttgaac tgattcatac cgattcgctg ccgctggtta
    44401 tttcactcaa cggtcatacg ctgcaggagt acatgcagga aactcgcagc tatgccttgc
    44461 aacctgttcc gtcaacgcag gcgtcgattc gcggggaaga gagtgagcaa atcgagctac
    44521 tcaatattcg caaagaaacg catgaagaat atgcgctgag tcgtccgcgc gggctgcgtg
    44581 aagcgttgct gatcgtcgcc tccttcctga tgttcttttt ctgcctgatt accccggatg
    44641 tatttgttcc gtggctgaca ggcggcgcgt tactgctgct gggcgcaggt ctgtgggggc
    44701 tattcgcgcc cccggcaaaa tcctccctgc gggaaattca ttgtctgcgc ggtacacccc
    44761 gtcgttgggg attgtttggc gaaaacgatc aggaacagat caacaatatt tcactcggta
    44821 ttatcgacct ggtctatccc gcacactggc agccatacat tgctcaggat ctcggtcaac
    44881 aaaccgatat cgatatctat ctcgaccgcc atgtagtgcg tcagggacga tatctttcac
    44941 tgcatgatga agtaaaaaac tttccgttac agcactggct gcgcagtacg attatcgctg
    45001 cgggctcgct gctggtgctg tttatgctgt tattctggat cccgctggat atgccgctga
    45061 aattcactct ctcatggatg aaaggcgcgc agaccattga agccaccagc gtaaaacaac
    45121 tggctgacgc tggcgtgcgg gtaggcgata cattgcgtat tagcggtacg ggaatgtgta
    45181 atattcgaac ttccggaacc tggagcgcga aaaccaattc acctttttta ccgtttgact
    45241 gctcgcagat catctggaac gacgcccgct cattgccatt accagaatct gaactggtca
    45301 acaaagcgac ggcattgact gaagcagtta atcgccagct gcaccctaaa ccggaagatg
    45361 aatctcgcgt cagtgcctca ttacgttcag caattcaaaa atccggcatg gtattgcttg
    45421 atgattttgg cgacattgta ctgaagacag cggatttatg ttctgccaaa gatgactgtg
    45481 tgcgactgaa aaatgcgctg gtcaatctcg gcaacagtaa agactgggac gcgctggtaa
    45541 aacgcgccaa cgccgggaag ctcgatggcg tgaatgtgtt attacgcccg gtgagtgcgg
    45601 aatcgctgga taacctagtg gcaacctcca ccgcgccatt tatcacgcat gaaacggcgc
    45661 gagcggcaca atcactaaac agtccggccc ccggcggatt cctgattgtc agcgacgaag
    45721 gcagcgattt tgttgatcag ccctggcctt cggcatcact ttacgactac ccgccgcaag
    45781 aacagtggaa cgctttccag aaactggcac aaatgctgat gcatacgccg tttaacgccg
    45841 agggtatcgt cacaaaaatc ttcactgacg ccaatggtac gcagcatatt ggccttcatc
    45901 cgatcccgga tcgttccggc ctgtggcgct atctcagcac cacattgctg ctactgacga
    45961 tgctgggtag cgccatttac aatggcgtac aggcctggcg tcgttaccag cgtcatcgca
    46021 ctcgcatgat ggagattcag gcctattatg aaagctgcct gaacccgcaa ctgatcaccc
    46081 cttcagaaag ccttatcgaa taacacgttt gcgcggcagg ttatgctacc ctgtcgcgca
    46141 aattgcttca ctctggagat ttccctcatg catatcaaca ttgcctggca ggacgtagat
    46201 accgttctgc tggatatgga cggcacgttg ctcgacctcg ccttcgataa ctatttctgg
    46261 caaaagctgg tgcctgaaac atggggcgcg aaaaacgggg ttacgccaca ggaagcgatg
    46321 gaatatatgc gccagcaata tcacgacgta cagcatacgc taaactggta ctgtcttgat
    46381 tactggagtg agcaactggg tctggatatc tgtgcgatga ccaccgagat gggaccgcgt
    46441 gccgtactgc gtgaagatac cattccgttt cttgaggcac tgaaagccag cggtaagcag
    46501 cgaattttgc tcaccaatgc gcatccgcac aacctggcgg taaaacttga gcataccggt
    46561 ctggacgcac accttgattt attactttcc acccacacat ttggttatcc gaaagaggat
    46621 cagcggttat ggcatgcggt ggccgaagct acgggtctga aagctgaaag aacgctgttt
    46681 attgatgaca gcgaagcgat tctcgatgct gccgcgcaat ttggtattcg ttactgcctc
    46741 ggcgtgacta atcctgattc cgggattgcc gagaaacagt atcaacgcca tccgtcactg
    46801 aatgactacc gccgcctgat cccctcgcta atgtgaagga gacgccatga aagagaaacc
    46861 tgctgttgag gttcgactgg ataaatggct atgggctgcc cgtttttata aaacccgcgc
    46921 gctggcccgt gaaatgattg aaggcggtaa ggtgcattac aacgggcagc gcagcaagcc
    46981 gagcaaaatc gtcgagctga atgccacgct cactctgcgc cagggaaatg acgaacgcac
    47041 ggtgattgta aaggcgatta ctgaacagcg tcgccccgcc agcgaggcag ccttgctgta
    47101 tgaagagact gcggaaagtg tagagaaacg cgaaaaaatg gcgctggcac gtaaacttaa
    47161 tgccttaacc atgccgcacc cggaccgacg cccggacaaa aaagagcgcc gcgacctgtt
    47221 acgatttaaa cacggcgaca gtgaataact gtcacctgca agagagatga ttatgccgca
    47281 acatgaccaa ttacatcgct atctgtttga aaactttgcc gtgcgcggcg aactggtaac
    47341 cgtttcggaa accctgcaac agatccttga gaaccacgat tatccgcagc ccgttaaaaa
    47401 cgtgctggca gaactgctgg ttgcgaccag cctgttaacc gctacgctga agtttgatgg
    47461 tgatatcacc gtacagctgc agggcgacgg tccgatgaat ctggcggtta ttaacggtaa
    47521 caataaccag cagatgcgcg gtgtggcgcg cgtgcagggc gaaattccag aaaatgccga
    47581 cctgaaaacg ctggtcggca atggttacgt ggtgatcacc attaccccga gcgaaggcga
    47641 acgctatcag ggcgtagttg gtctggaagg tgataccctg gcggcctgcc tggaagatta
    47701 ctttatgcgt tctgaacagc tgccgacgcg cctgtttatt cgcaccggcg acgtagacgg
    47761 caaaccggct gcaggcggta tgttgttgca ggtaatgcct gcgcaaaatg cccagcagga
    47821 cgactttgac cacctggcga cgctaaccga aaccatcaaa accgaagaac tgctgacctt
    47881 accggcaaac gaagtgttgt ggcgtttgta tcacgaagaa gaggtgacgg tttacgatcc
    47941 gcaggatgtg gagttcaaat gcacctgctc gcgtgaacgt tgcgccgatg cgctgaaaac
    48001 gctgcctgat gaagaagttg atagcatcct ggcggaagat ggcgaaattg acatgcattg
    48061 tgattactgc ggtaaccact atctgttcaa tgcgatggat attgctgaaa tccgcaacaa
    48121 cgcgtctccg gcagatccgc aagttcatta atgagtatgt ccggcagaga gggctctgcc
    48181 ggattttacg actaatacac ctgatgcgct ttgtcactca ttcagattca cattcagcct
    48241 ttcaccatcc actacaagat cgcgccacgc tttaggcttc gtccccagtt ttccatcctt
    48301 cgcagctgtg agtaattttt ctttcgttat ttcgttcgga agtaaactca tatcaagcgc
    48361 gtcccattct tttctgtctg agtcaaagcc atagacaatg actctgtcat cattaaaagc
    48421 aaacaggatc cgctccgcct gaccatcact attcagatct tgctcgacca ggacgcaggc
    48481 gtctttttca atacaggtca tcacgttata gcgatcctgg attaaggccg accagaatgt
    48541 cgcatcaggt ttaacagaac caggggcaat taacacatta tcggctaata ctttttccga
    48601 tacctgttgc tgaagatgtt gctctccatc taacgccatc agcagatccc gcgcgcgttt
    48661 cgggtctttc ataaacccgg catcgctttt cagcgactca agcgcagcac gtccatagcg
    48721 accgctctgc tcgagcatgt agatagttac ctggtctgac gtgtttttgc cgctctgata
    48781 acgcgccata tggctgttca cgctaatgcg catactgtcc agcaccggcg aattaagaag
    48841 caccagtatc accaacacca ataacgaaac cgcaaggttc actttgccct gaagaacaac
    48901 gggattttgc cctttacgcc agacgatgct gacaaaatac cccagcgacc acaccagtaa
    48961 caccagcacc gccagcacgc cctgcaagcg gtcgacagtc cagccgtact gagcgacccg
    49021 cagccataac gcccaggcgg cgacgaacac atacagcgga gcaaccagca aagcggtttt
    49081 aatcaggcaa cgcaacggcc ctgtccaggg aagtgacgct ttttgcggat cgcggacaat
    49141 agccattaag atcaattgca aaaaggccag cgtcaacagc aacccggcgg cggagatgtg
    49201 gcgagaaatc gcgctcaggc ccgtaaacgg cagggtgatg ataaacatca gggttagcaa
    49261 tgatactaac ggcagcaacc ccgtggcgat taacgtgaac aacttttgaa tagagtcgat
    49321 taaacgtgac tgtgttcgcg cgaggatcac cgccagcgcg gtaaccagac ctaacgtgag
    49381 ataaataaac cagtcggttg caaaaaagag cgtattgaaa aacgtgatgc caacaagttt
    49441 aaacaactca ctccacagta aaagcaccag ccacgtcaag ccattggcga gaaaaatcac
    49501 cagtaatata agtacgttat gccatactga ctggtaaaaa tagcgatagc ggctactgtc
    49561 attgcggatg cgaaggcttt gttgtatcca cggtagcaac aacattgcca tcaacagcag
    49621 atagcaacca aaatcccaaa gcgccttttc agctctccag gggttcatgc catcagtttg
    49681 ccacttcagc cagccgctca tccccagcgt ggcaataaac actagcgcca gccatcccca
    49741 aaggcgcttc tgtttaaaag agatcacgga gaagagtaaa acggatgaaa acgcgacggt
    49801 cgcaggcacg ccataaacaa tccaactgtg attttttccg gaaagccagg cgatcagcag
    49861 gtagcaaacc agaccctgaa gtaatccggt agcaatcatc ccccagcgtg ttgcgggtga
    49921 aagttcaacg ttatccatgt tggttatcca gaatcaaaag gtgggttaat tatcgcatcc
    49981 gggcagtagt attttgcttt tttcagaaaa taatcaaaaa aagttagcgt ggtgaatcga
    50041 tactttaccg gttgaatttg catcaatttc attcaggaat gcgattccac tcacaatatt
    50101 cccgccatat aaaccaagat ttaacctttt gagaacattt tccacaccta aaatgctatt
    50161 tctgcgataa tagcaaccgt ttcgtgacag gaatcacgga gttttttgtc aaatatgaat
    50221 ttctccagat acgtaaatct atgagccttg tcgcggttaa cacccccaaa aagactttac
    50281 tattcaggca atacatattg gctaaggagc agtgaaatgc gcgttaacaa tggtttgacc
    50341 ccgcaagaac tcgaggctta tggtatcagt gacgtacatg atatcgttta caacccaagc
    50401 tacgacctgc tgtatcagga agagctcgat ccgagcctga caggttatga gcgcggggtg
    50461 ttaactaatc tgggtgccgt tgccgtcgat accgggatct tcaccggtcg ttcaccaaaa
    50521 gataagtata tcgtccgtga cgataccact cgcgatactt tctggtgggc agacaaaggc
    50581 aaaggtaaga acgacaacaa acctctctct ccggaaacct ggcagcatct gaaaggcctg
    50641 gtgaccaggc agctttccgg caaacgtctg ttcgttgtcg acgctttctg tggtgcgaac
    50701 ccggatactc gtctttccgt ccgtttcatc accgaagtgg cctggcaggc gcattttgtc
    50761 aaaaacatgt ttattcgccc gagcgatgaa gaactggcag gtttcaaacc agactttatc
    50821 gttatgaacg gcgcgaagtg cactaacccg cagtggaaag aacagggtct caactccgaa
    50881 aacttcgtgg cgtttaacct gaccgagcgc atgcagctga ttggcggcac ctggtacggc
    50941 ggcgaaatga agaaagggat gttctcgatg atgaactacc tgctgccgct gaaaggtatc
    51001 gcttctatgc actgctccgc caacgttggt gagaaaggcg atgttgcggt gttcttcggc
    51061 ctttccggca ccggtaaaac caccctttcc accgacccga aacgtcgcct gattggcgat
    51121 gacgaacacg gctgggacga tgacggcgtg tttaacttcg aaggcggctg ctacgcaaaa
    51181 actatcaagc tgtcgaaaga agcggaacct gaaatctaca acgctatccg tcgtgatgcg
    51241 ttgctggaaa acgtcaccgt gcgtgaagat ggcactatcg actttgatga tggttcaaaa
    51301 accgagaaca cccgcgtttc ttatccgatc tatcacatcg ataacattgt taagccggtt
    51361 tccaaagcgg gccacgcgac taaggttatc ttcctgactg ctgatgcttt cggcgtgttg
    51421 ccgccggttt ctcgcctgac tgccgatcaa acccagtatc acttcctctc tggcttcacc
    51481 gccaaactgg ccggtactga gcgtggcatc accgaaccga cgccaacctt ctccgcttgc
    51541 ttcggcgcgg cattcctgtc gctgcacccg actcagtacg cagaagtgct ggtgaaacgt
    51601 atgcaggcgg cgggcgcgca ggcttatctg gttaacactg gctggaacgg cactggcaaa
    51661 cgtatctcga ttaaagatac ccgcgccatt atcgacgcca tcctcaacgg ttcgctggat
    51721 aatgcagaaa ccttcactct gccgatgttt aacctggcga tcccaaccga actgccgggc
    51781 gtagacacga agattctcga tccgcgtaac acctacgctt ctccggaaca gtggcaggaa
    51841 aaagccgaaa ccctggcgaa actgtttatc gacaacttcg ataaatacac cgacacccct
    51901 gcgggtgccg cgctggtagc ggctggtccg aaactgtaat gatttgaagc tggagaatat
    51961 ctatccagta tcttatagaa agcaaaacgg gaggcacctt cgcctcccgt ttatttaccc
    52021 ttcttttgtc gtgccctgcg cccgcgttac cggcactggc agccaggcgc gaatggaaag
    52081 cccgccccgc tcgctggtgc caagctccag catcccgtta tggttatcca cgatacgctg
    52141 cacaattgcc agccctaatc ccgtgccgct aatggtgcgc gcactgtcgc cgcggacaaa
    52201 cggctggaac aggtgcttac gttgttccgg cgcaattccc ggaccgtcat cttccacctg
    52261 gaaccaggcg cgattcggct ccgttccgct gctgactttg atccagccat tgccataacg
    52321 ggcggcgttg accaccatat tcgccaccgc gcgtttgatc gacagcgggt gcattttcac
    52381 ttcaatgctg ccggggtaaa gcgcggtttc aatttcccgc tcatagccac tttcggcagc
    52441 aatcacctca ccgagtactg cattaagatc cgccatttcc atcggcatct cctgcccggt
    52501 gcgcaggtag tcgataaact gctcaatgat ggcgttgcac tcttcgatat ctttattgat
    52561 cgattctgcc agatagccat cctgctcgct catcatctca gtcgccaggc gaatacgcgt
    52621 cagcggcgtg cgcaagtcgt gacttacccc cgccatcagc agcgtgcggt catccgccag
    52681 ttgcttaaca ccagccgcca tatggttaaa ggcacgggta acggaacgca cctccgaagc
    52741 gccatactca cgcagcggcg gcggaataat ccctttacca acctgcaagg ctgcgtgttc
    52801 gagatcgacc aacggtcggt tctggatacg aataaacagc cacgccccgc ctatcgccaa
    52861 tagcataatc gccagcgtat agcggaacag cggagagaaa tcgccctgat gaatttcggt
    52921 cagcggcacg cgtacccaga tattgggcga cagccaggtt ttcagccaga cgacaggcga
    52981 acttttgttg acctcaacgc gcacttccgt cgggccgccc agttgctgcg ccatctgatg
    53041 gcttaagaat tcatagtgtt gcgcccaacg cagacctgcc tcttcggcag cctcgttgga
    53101 gtagagagag atccccagct cacggtagat ctcccgacgg aaagcgggag gcacaaccaa
    53161 ctgcgtgccg tcctccagtt gcagtttgtc ggtcatcaac atacgcactt cgtacgcgag
    53221 gactttatta aactgctgga ggctcggcaa aatcgcgaag ttcagcacca ccagataagt
    53281 cgtcaccagg ctggcgaaca gcaaggtgac gatgagcaat aacgtacggg caaatgaact
    53341 tcgtggcgag aagcgcaatc gcctcatgct ttagagccgt ccggtacaaa gacgtagccc
    53401 agaccccaga cggtctgaat gtaacgcgga tgcgctggat cttcttccac catgcggcgc
    53461 agacgcgaaa tctgcacgtc gatggagcgt tccattgcgg aatattcacg accacgggca
    53521 aggttcatca gcttatcgcg ggagagcggc tcacgcggat ggctgaccag tgccttcagt
    53581 accgcaaact caccgctggt gagcggcatc ggctcgtctt cgcggaacat ttcgcgcgta
    53641 ccgaggttaa gtttgaactt accgaaagca attaccgcct cttcctgtga cggtgcgcct
    53701 ggcagttcgt tcgcctgacg acgcagcacc gcacggatac gggccagcag ttcacgcggg
    53761 ttaaacggtt ttggaatgta gtcgtcagcg ccaatctcca ggcctacgat acggtccact
    53821 tcttcccctt tcgccgtcac cataatgatc ggcatcgggt tgctctgact acgaagacgt
    53881 cggcaaatcg acaagccatc ttcaccaggt aacattaaat ccagtaccat aagatggaaa
    53941 gattcacgag tcagcaggcg atccatctgt tctgcattag cgacgcttcg aacctggaag
    54001 ccttgttcgg tgagataacg ttccagcagc gcacgcaggc gcatgtcgtc atcgaccacc
    54061 agaatcttgt agttctcttg cattgtttgt actcccaaag gttcgcaaca atttgtaagc
    54121 gtgtattctt aaaaaagctc acgttcgtca ccagctaaat ctggtatgaa tttcagccta
    54181 aattgttaca aagcatatta aacagcagct taagtataca atttattcgg cgaaacatta
    54241 ttgattctgt tgatatgatc acgttatacc caatgtgcgc attatcaaac agacaaaggg
    54301 aatcaacgag atgaaaacgc ccctggttac ccgggaaggg tatgaaaaac tcaaacaaga
    54361 gcttaattat ctctggcgtg aagaacgccc ggaggtcaca aaaaaggtga cctgggccgc
    54421 aagtctgggc gaccgcagcg aaaatgctga ctatcagtat aataaaaagc gtctgcgtga
    54481 aatcgaccgt cgcgtgcgct atctcactaa atgcctggaa aatctcaaaa tcgtcgatta
    54541 ctcccctcag caggaaggca aagtcttttt tggcgcgtgg gtggagattg aaaacgacga
    54601 tggcgtgact caccgtttcc gtattgtcgg ctacgatgaa atttttggcc gtaaagatta
    54661 catctctatc gattccccga tggcccgcgc attgctgaaa aaagaagtcg gcgatctggc
    54721 ggtggtgaat acccctgccg gggaagcgag ctggtatgtt aatgctatcg agtacgtgaa
    54781 accgtaagga agagtcttaa cctcctgccg atggctggca tttttgccag ccagtccgta
    54841 taactatccc ctgatttttg atccgaaaag atgaactcaa accatgatga atgattcgtt
    54901 ctgccgcatt attgcgggtg aaattcaggc gcgcccggaa caggttgacg ctgccgttcg
    54961 cctgcttgac gaagggaata ccgtgccgtt tatcgcacgt tatcgtaagg aaatcaccgg
    55021 cggtctggat gacacgcagc tgcgtaatct ggaaacgcgt ctgagctatc tgcgcgagct
    55081 ggaagagaga cgtcaggcga tcctcaagtc catttccgag caaggcaaac tcaccgatga
    55141 tctggcgaag gccatcaacg ccaccctaag caaaaccgaa ctcgaagacc tctacctgcc
    55201 ctacaaacct aaacgccgca cccgcgggca aatcgccatt gaagcagggc ttgagccgtt
    55261 ggctgacctg ctgtggagcg atccgtcaca cacgccagaa gtcgccgctg cacaatatgt
    55321 tgatgccgat aaaggcgtgg cagataccaa agccgcgctg gatggcgcgc gctatatcct
    55381 gatggaacgg tttgccgaag atgccgcgct gctggcgaaa gtgcgtgatt atctgtggaa
    55441 gaacgcgcat ttggtttcta cggtggtgag cggtaaagaa gaggaagggg cgaaattccg
    55501 cgactatttc gatcatcacg aaccgttgtc cacggtgcct tctcaccgcg cgctggcgat
    55561 gttccgtggg cgtaacgaag gcgtacttca gctttcgctg aatgccgatc cacagttcga
    55621 tgagccgccc aaagagagct attgcgagca aatcatcatg gatcaccttg gcctgcgcct
    55681 gaacaatgcc ccggcggata gctggcgcaa aggcgtggtg agctggacgt ggcgcatcaa
    55741 ggtgctgatg catctggaaa ccgaactgat gggcaccgtg cgcgaacgtg cggaagatga
    55801 agcaatcaac gtctttgccc gtaacctgca cgatctgctg atggcggccc ctgccggact
    55861 gcgtgcaacg atgggcctcg atccgggtct gcgtactggg gtaaaagtgg cggtggtcga
    55921 tgccactggc aaactggtgg cgaccgacac catttacccg cacaccggac aggccgcaaa
    55981 agcagcgatg accgttgctg cgctgtgtga aaaacataac gttgaactgg tagcgatcgg
    56041 taacggtaca gcttcccgcg aaactgagcg tttctatctc gatgtgcaga agcagttccc
    56101 gaaagtgacc gcgcagaaag taatcgtcag cgaagcaggc gcgtcggttt actcggcttc
    56161 cgagctggct gcacaggagt tcccggatct cgacgtttcg ctgcgtggcg cggtgtctat
    56221 cgcccgccgt ttgcaggatc cgctggcgga gctggtgaaa atcgatccga aatctatcgg
    56281 cgtaggtcag tatcagcatg acgtcagcca gacgcaactg gcccgcaaac tggacgcagt
    56341 agtagaagac tgcgtaaacg ccgttggcgt cgatctcaac actgcttctg ttccgctgtt
    56401 aacccgcgtg gcgggcctga cgcgcatgat ggcgcaaaac atcgttgcct ggcgcgatga
    56461 gaacggtcag ttccagaacc gtcagcaact gttaaaagtg agccgtctgg ggccgaaagc
    56521 cttcgagcag tgcgcgggct tcttgcgcat taaccacggt gataacccgc tggacgcgtc
    56581 taccgttcac ccggaagcct atccggtggt ggaacgcatt ctggcagcaa cacagcaggc
    56641 actgaaagat ctgatgggta acagcagcga actgcgtaac ctgaaagcgt ctgactttac
    56701 tgatgagaaa ttcggtgtgc cgacggtaac cgacatcatc aaagagctgg aaaaaccggg
    56761 tcgcgatccg cgtccggaat ttaaaaccgc tcagtttgcc gatggcgtcg agacaatgaa
    56821 cgacctgcaa ccgggtatga tcctcgaagg cgcagtgacc aacgtcacca actttggcgc
    56881 gtttgtcgat attggcgtgc atcaggacgg cctggttcac atctcttcat tgtcgaacaa
    56941 gtttgtggaa gatccgcata ccgtggtgaa agcgggcgac attgtgaagg tgaaagtgct
    57001 ggaagtggat cttcagcgta aacgtatcgc cctgactatg cgcctggatg agcagcctgg
    57061 cgaaaccaac gctcgtcgcg gcggcggtaa tgaacgcccg caaaacaacc gcccggcagc
    57121 caaaccacgc ggtcgtgaag cgcagcctgc cggtaatagc gcgatgatgg atgcgctggc
    57181 ggcggcaatg ggcaaaaaac gttaaacgcc cgtactggcc tacggttcga atttgcacga
    57241 aatcgtaggg cagataaggc gttcacgccg catctggcaa cgaacgcctt gcctgacata
    57301 aaagtgccgg agaatatctc cggcattttt attccacagc caaactcata atatattccg
    57361 gcaatattta tcatttcatt aacaactgaa accttaatta aacattagcc agtccgggta
    57421 attcactatt cgaattatat tttcgctgcg atataacctt gagccacatc aacattgagt
    57481 cagattatta ttcaaaccaa cattcgcaca cattttaagt attgctgata gaaaccattc
    57541 tcattatcat tgtgttgttg attatttaat ctctcctttg ttggcaaatc atctggtctc
    57601 atgtcgctgt caaacgcccc atgaggtagt tatccagtta atgagaaaca agtaggcacc
    57661 tatgcaatac actccagata ctgcgtggaa aatcactggc ttttcccgtg aaatcagccc
    57721 ggcatatcgc caaaaactgc tttctcttgg catgttacct ggctcctctt ttaatgtggt
    57781 gcgcgtcgct ccactcggcg accccattca tatcgaaacc cgtcgtgtga gcctggtatt
    57841 acgcaaaaaa gatctggcct tattagaagt ggaagcggtt tcctgttaat acggtgataa
    57901 caacaatgaa aaaattaacc attggcttaa ttggtaatcc aaattctggc aagacaacgt
    57961 tatttaacca gctcactggc tcacgtcagc gtgtaggtaa ctgggctggc gttaccgtcg
    58021 aacgtaaaga agggcaattc tccaccaccg atcatcaggt cacgctggtg gacctgcccg
    58081 gcacctattc tctgaccacc atctcatcgc agacctcgct cgatgagcaa atcgcctgtc
    58141 actacatttt gagtggcgac gccgacctgc tgattaacgt ggtggatgcg tctaaccttg
    58201 agcgtaacct gtacctgacg ctacaactgc tggaactcgg cattccctgc attgtggcac
    58261 tgaacatgct cgacattgcc gagaagcaaa atattcgtat tgaaattgat gctctgtcgg
    58321 cgcgtctggg ctgtccggtg atcccgctgg tttcaacccg tggtcgcggt attgaagcgc
    58381 tcaagctggc gattgatcgc tataaagcta acgagaatgt ggaactggtg cattacgcac
    58441 agccgctgct caacgaagca gattcactgg caaaagtgat gccttccgac atcccgctga
    58501 aacaacgtcg ctggctgggc ctgcaaatgc tggaaggcga tatctacagc cgcgcctacg
    58561 ccggtgaagc gtcgcagcat ctggatgccg ccctcgcccg tctgcgtaat gagatggacg
    58621 atccggcgct gcacattgcc gatgcgcgtt accagtgcat tgctgccatc tgtgatgtgg
    58681 taagcaacac cctgacggca gaacccagcc gtttcaccac tgcggtagat aaaatcgtgc
    58741 tcaaccgttt cctcggtctg ccgattttcc tctttgtgat gtacctgatg ttcctgctgg
    58801 ctatcaacat cggcggggcg ttacagccgc tgtttgacgt cggctccgtg gcgctatttg
    58861 tgcatggtat tcaatggatt ggctacacgc tccacttccc ggactggctg actatcttcc
    58921 tcgcccaggg cctgggtggc ggcattaaca ccgtgctgcc actggtgccg cagattggca
    58981 tgatgtacct gttcctctcc ttccttgagg actccgggta tatggcgcgt gcggcgtttg
    59041 tgatggaccg tctgatgcag gcgctgggct tgccggggaa atcctttgtg ccgctgatcg
    59101 tcggtttcgg ttgtaacgta ccgtcggtaa tgggtgcacg tacgcttgat gcaccgcgtg
    59161 aacgtctgat gaccatcatg atggcaccgt ttatgtcctg cggcgcgcgt ctggctatct
    59221 tcgcagtatt cgcggctgcc ttcttcgggc agaacggtgc gctggcggtc ttctcgctgt
    59281 atatgctggg tattgtgatg gcggtgctga ctggcctgat gctcaagtac accatcatgc
    59341 gcggtgaagc gacgccgttt gtcatggagt tgccggtcta tcatgtacca cacgttaaaa
    59401 gcctgattat ccagacctgg cagcgtctga aaggcttcgt tctgcgtgct ggtaaagtga
    59461 tcatcatcgt cagcattttc ctgagcgctt tcaacagctt ctcgctgagc gggaaaatcg
    59521 tcgataacat caacgactcg gcgctggcgt ccgtcagccg ggtgatcacc ccggtcttca
    59581 agccaattgg cgtgcatgaa gataactggc aggcaacggt tggcctgttt acaggtgcca
    59641 tggcgaaaga agtggtagtg ggtacgctca acaccctcta caccgcagaa aatattcagg
    59701 acgaagagtt caatccggca gaatttaacc tcggtgaaga gctgttcagt gcgatagatg
    59761 aaacctggca gagcctgaaa gacaccttca gccttagcgt actgatgaac cccattgaag
    59821 ccagcaaagg cgacggcgaa atgggtaccg gggcgatggg cgtgatggat cagaaattcg
    59881 gtagcgcagc agcagcttac agctacctga ttttcgtcct gctgtatgta ccatgtatct
    59941 cggtgatggg ggctatcgcc cgtgaatcaa gccgtggctg gatgggcttc tccatcctgt
    60001 gggggctgaa tatcgcttac tcactggcaa cattgttcta tcaggtcgcc agctacagtc
    60061 agcatccaac ttacagcctg gtgtgcattc tggcggttat cctgtttaac atcgtggtta
    60121 tcggtctgct gcgccgcgcg cgtagccggg tggatatcga actgctggca acccgcaagt
    60181 cggtaagcag ttgctgcgca gccagcacca ccggtgattg ccattaatgg cttcacttat
    60241 tcaggtgcgc gatttgctgg cgttacgggg ccgtatggaa gcggcccaga taagccagac
    60301 attgaacact ccacagccaa tgattaacgc catgctgcaa caactggaaa gtatgggcaa
    60361 agccgtgcgg attcaggaag aacctgacgg ctgcctctct ggcagttgta aaagctgccc
    60421 ggaaggaaaa gcctgtctgc gcgagtggtg ggcgctgcgt taaccttact ccatcgcctg
    60481 ttttggaaag cccggtatgc gtctgcatcc gggctttttt gcgtgcggct ttccataaaa
    60541 atgcaactct tgcagcacgg cgtaagttcc tttgaaagca tctcgcaggg atgaaaactc
    60601 gctaatacac aggtgtggag tggcgcgtag agtcgcggca ttcaaacaac aggtgaagga
    60661 acgccatgag caaaaagcag agttccaccc cacacgatgc gctgttcaaa ctctttttac
    60721 gccaaccgga cacggctcgt gattttcttg cgtttcattt accggcaccc attcacgcgc
    60781 tttgtgatat gaaaaccctc aagctggagt cgagcagctt tattgatgac gatctgcgtg
    60841 aaagctattc cgatgtgctg tggtcggtga aaacggaaca aggaccagga tacatctatt
    60901 gtctgattga acatcaaagc acctcaaaca aactgatcgc atttcgcatg atgcgttacg
    60961 ctattgccgc aatgcaaaat caccttgatg ctggatacaa aacgttgccg atggtggtgc
    61021 cattgttgtt ttaccacggt attgaaagcc cctatcccta ttcgctgtgt tggctggatt
    61081 gtttcgccga tcccaaactg gcaaggcagc tttatgcctc cgcatttccg ctgattgatg
    61141 tcaccgtcat gcctgatgat gaaatcatgc agcaccgacg tatggcgctg ctggagttaa
    61201 ttcaaaaaca tattcgtcaa cgcgacctga tggggctggt agagcaaatg gcctgcttat
    61261 taagtagtgg atacgctaat gacagacaaa tcaaagggct gtttaattac atactgcaaa
    61321 ctggcgacgc tgtacgtttt aacgatttta tcgacggcgt tgccgaacgt tcaccgaaac
    61381 acaaggagag tttaatgact attgcggaaa gattgcggca ggagggggaa caatccaaag
    61441 ccctgcatat agccaaaata atgcttgaat ccggagttcc tcttgcagac atcatgcgct
    61501 ttaccgggct gtcagaagaa gagttggctg cggcgagtca gtaaagttct gtctcgccat
    61561 ttcaaaagcc acctacaccc tctgcttcaa cgccaccagc aggtgacaaa actcggccgg
    61621 atgcgaaata aatggcgcat gggccgcttt ggcgaagata tatgattcgc tgtgaggcca
    61681 aagtttatcc agcatcggca ccactttgcg cggcaccaga ccgtcgagat agccatacaa
    61741 tcgcaaaaac ggcatggaca cgttttgcag cggctgacgg agatcgaccg ttttcaggat
    61801 ttccagcccg ccattaagca cgtcaacctc cggcatcggt aacgccagaa cggttttctt
    61861 caacgcccgc gcatcctggc gcgccgtttc agtccccatg gtttgtaacg ccaggaaccg
    61921 ctccactgta cgctgaaaat catcactgag ttgctgctga aatcccgcca gcacgtccgg
    61981 ttttatcccc ggccactcgt cacgagcact aaaacaaggt gacgacgcca cggtgaccag
    62041 cgcctgaaca cgctcgggat gggttaacgc aatctggctt gccaccagcc cgcccagact
    62101 ccagcctaac caaatggctt tatcaggtgc ctgttgcagc acggcttcgg ccatatcagc
    62161 aagtgacagc gcaccaaatc cccggctacg cccgaagccg ggcaggtcaa caaggtgcag
    62221 cgtaaaatgc gagctaagtt cctcgtcaat gcaacgccac acttcggcat tcagtcccca
    62281 tccgtgcagc agcacaagat gaacattccc ctgacctttg gtctgccacc agatgttatt
    62341 catccgctat tgttctcttt tgacttacaa ggatgaacat atgctaacag taccgggatt
    62401 atgctggcta tgccgaatgc cactggcgtt aggtcattgg gggatttgtt cggtctgttc
    62461 acgcgccacc cgcacagata aaacgttatg cccacaatgt ggattacccg ccacacactc
    62521 ccatcttccc tgcggtcgct gcctgcaaaa accgccgccc tggcaaagac tggtcacggt
    62581 tgccgactat gcgccgccgt taagtccgct tatccaccag cttaaatttt cccggcgcag
    62641 tgaaatcgcc agcgccctgt cacgtctgtt actattggaa gtcttacacg ctcgtcgcac
    62701 caccgggttg caattgccgg atcgcatcgt cagcgttccg ttatggcagc ggcgtcactg
    62761 gcgtcgggga tttaatcaga gcgatttgct gtgtcagccg ttatcacgct ggttgcactg
    62821 ccaatgggat agcgaagccg tcacacgtac acgggccact gcgacccagc attttctcag
    62881 tgcccggctg cgcaagcgca acctgaaaaa tgcctttcgt cttgaattgc ccgtgcaagg
    62941 tcgccatatg gtgattgtgg atgatgtcgt taccaccgga agtaccgtcg cagagattgc
    63001 gcagttgctt ttacgcaatg gtgcggcggc tgtccaggtc tggtgccttt gtcgaacctt
    63061 gtagagcctc gatgatgggc gtattataac caactaaaat agtcaactat taggccatta
    63121 ctatgatccg tatttccgat gctgcacaag cgcactttgc caaactgctg gcaaatcagg
    63181 aagaagggac acaaatccgc gtatttgtga ttaaccctgg cacgcctaac gctgaatgtg
    63241 gcgtttctta ttgtccgccg gacgctgtgg aagccaccga cacagccctg aaatttgacc
    63301 tgctgaccgc gtatgttgat gagttaagcg caccatacct ggaagatgca gagatcgatt
    63361 ttgttaccga ccagttgggt tcccagttaa cgctgaaagc cccgaacgcc aaaatgcgta
    63421 aagtggcaga cgatgcaccg ctgatggagc gcgtggagta tatgctgcag tcgcagatca
    63481 acccacagct tgctggtcac ggtggtcgcg tttcgctgat ggaaatcacc gaagacggtt
    63541 acgccattct gcaatttggc ggcggctgta acggttgttc catggtcgat gtgacgctga
    63601 aagaagggat cgagaagcag ctgctgaacg aattcccgga gctgaaaggt gtgcgcgatc
    63661 tcaccgaaca ccagcgcggc gaacactcct actactaagt tatcccctct tttgtagatt
    63721 gcccgatgcg acgctaaagc gtcatttcgg gcctacgttg aacatgtgcc agacgttggc
    63781 gcagcattgc tttgtcaaat cctcggttcg tttccccgcg ataatatgac caacctctca
    63841 taatttaaat ttaccccgct ctggtgattc tcaaacgcca gatgttaccc gtatcattca
    63901 catgggtacc aaacatactc ctgacatctg actacaataa ttagttttag tgggtatcag
    63961 tcgtggtgcc gcaatatctc tgttcccgat tgggataatt agagtttgtc gtcagaaaat
    64021 tgacgttacc cataacaaat gaaaggccag gtaaatcatg ccattagtca ttgttgctat
    64081 cggtgtaatc ttgttgttgc tcctgatgat ccgcttcaaa atgaacggct tcatcgctct
    64141 cgtcctcgtg gcgcttgctg ttggattaat gcaaggaatg ccgctggata aagttattgg
    64201 ctccatcaaa gccggtgtcg gcgggacgct cggtagcctt gccctgatca tgggttttgg
    64261 cgcaatgctg ggcaaaatgc tggcagactg cggtggcgca caacgtatcg ccaccacgct
    64321 gattgccaaa tttggtaaaa aacacatcca gtgggcggtg gtactgaccg gttttaccgt
    64381 tggttttgcc ctgttctatg aagtgggctt tgtgctgatg ctgccgctgg tgtttaccat
    64441 cgcggcttct gcgaatattc cactgctgta tgttggtgta ccaatggcgg ctgcactgtc
    64501 tgtgacccac ggcttcctgc caccgcatcc gggtccgact gcgattgcca ccattttcaa
    64561 tgccgatatg ggtaaaaccc tgctgtacgg tactattctg gcaatcccga ccgtgattct
    64621 cgccggtccg gtttacgctc gcgtgttgaa aggtatcgat aagccaattc cggaaggtct
    64681 ctacagcgcg aaaaccttca gcgaagaaga gatgccgagc tttggcgtca gcgtctggac
    64741 ctctctggtg ccggtagtac tgatggcgat gcgtgcgatt gccgaaatga tcctgccgaa
    64801 aggtcacgct ttcctgccgg tagcggagtt cctcggtgac ccggtaatgg caacgctgat
    64861 tgccgtgctg attgcgatgt tcacctttgg tctaaaccgt ggtcgttcaa tggatcagat
    64921 taacgacacg ctggtttctt ccatcaaaat cattgcgatg atgctgttga tcatcggtgg
    64981 tggcggtgcg ttcaagcagg tgctggtaga cagcggcgtg gacaaataca ttgcttccat
    65041 gatgcacgaa accaacattt ctccgctgct gatggcctgg tcgattgctg ccgtactgcg
    65101 tatcgcgctg ggttccgcaa ccgttgcggc aatcactgcg ggtggtatcg cggcaccgct
    65161 gattgcaacg acgggtgtta gcccggagct gatggttatt gcggttggtt ccggtagtgt
    65221 gattttctct catgtgaacg atccgggctt ctggctgttc aaagagtact ttaacctgac
    65281 tatcggcgag accatcaaat cctggtcgat gctggaaacc attatctcgg tgtgcggtct
    65341 ggtaggctgt ctgctgctga atatggtgat ttgataacac tgactgccgg atgcggcgtg
    65401 accgccttat ccggcctacg attcgggatg aattagtagg ccggataaga cgcgtcaagc
    65461 atcgcatccg gcatcaaccg cactctactt cttcttcgct gcagctctgc gccgtctgtc
    65521 caaatccttc agcaacttgt tcacgccatc atcggcaaac atcgactcaa gcgttgcgga
    65581 aagcttgcgt cgccagtttt tatactggta actggtgcca ggaatattca ccggttcggc
    65641 catatccagc cagtcttccg gctgtagtcc taacagagca ctgttactgt cggcaatgta
    65701 gcgctgcaaa ccacggttca gcgtcggcgt catcgacatc aacgatgcct tatgcccggc
    65761 acgtttcggc agacaaccat atttatgcag tgcatccagc agcccttgct tcgccagttc
    65821 gcgatcctga tacagaccgc gcagtaccac ttcatccgga tacagcccca gggttttgcc
    65881 cagcgttaga tccccgctct cccagtaacc gcgcagcgtt ggcaggtcat gtgtcgccgc
    65941 aaccgccatc gactgctccg gatacgcttt cggtgcacgg aacgtcttct cgtggtcgtt
    66001 ttcgaaatag agcactttgt aagagtacac accgctgctg cgcagcttac cgacaatctc
    66061 taccggtacg gtaccgagat cttcaccaat caccatacag cgatgacgtt tactttcgag
    66121 tgccagaatc gagagcagat catccaccgg atagtgaaca tacgcgccct gatctgccgt
    66181 ctcgccatac ggtatccacc acaaacgcag catcgacatc acatggtcaa ttcgtaatgc
    66241 gccgcagttt tgcatattgg cacgcaacag ctcgataaac ggttcatagg cacgcgcggt
    66301 gatgatatgc gggtccattg gcggtaatcc ccagttctgc cccaacgggc cgaggatatc
    66361 cggcggcgcg ccaaccgatg ctttcaggca atatagttca cggtcacacc aggtttccgc
    66421 cccaccttcc gctacgccaa ccgccagatc acgatacaag ccaatcggca tttcatagcc
    66481 ctggcttatc tcccagcagg cggcaaactg gctgtaagcc agccactgca accagagata
    66541 aaaatcgacg tcatcacgat gttcttcgca gaactgacgc acttctggtg aatccacgtt
    66601 ctgatacatc tctggccatg caggccagcc ccagcgcatt tcgtcctctt tcacttgctg
    66661 ggcatgtagc gcatcaaagg ctgcctgcca gaacaggctg tcgccctgct ctgcaacaaa
    66721 ctggcgaaac gcggccatct gctcatcatc acgttgcgcg aaacctttcc acgccattcg
    66781 taatgctgtc atttttaggg cggtaaccgt ggagtaatcg acccagtcgg catcgcgcgc
    66841 ctgttgcagc gtctgttgcg tggtcggcaa ctgccaccag gcctgagcct cttcgctaag
    66901 atggaaatct tcaacggcgt taacgtcgat ataaatcaca ttcagccaac ggcgagaaga
    66961 cgggctgtat gggctggcgc tctccggatt tgccggatag agcgcatgaa tcgggttcag
    67021 gccaatgaac gacccgccac gttttgccac atccaccagc atcgctttga gatcgccaaa
    67081 atccccaata ccccagtttt tttccgatcg cagcgtataa agctgaacgc aggcacccca
    67141 cagcttttgt ttattcagca acgcctgcgg ttcgtaacag cgtttcgggg cgacaatcac
    67201 ccggcaatgc gcgcgctggt cgtcctgggt gagtgtcagc gtgtgataac cttccggcag
    67261 cttcgtcggt agattgaacg ctttgccccc cgttacatgg cctttgtact gcgttccttc
    67321 ttcggtggtc agcagccagc tatattcgcc gctgccctcc accaccatcg gcattttttt
    67381 gccgctggta taaaccatga cattcgggac tggcgttacc gccactttcg tggcggtacg
    67441 ttgatgcatc gcgtcaagca aacgccgttt ggtttcggcg ctaatcgact gcggtttacc
    67501 gtgggcattg atgtaattgg ggctaatccc cgccgccagc gcggcattat ccagacgttt
    67561 gctttccatc gagcttcctt agcgttttgc ctgccagata cgagcctgat aatcgcgaat
    67621 agagcgatcc gagctaaaca taccgcagcg ggcggtattg aggatcgccg cgcgagtcca
    67681 ggcctcctgg tcgcggtaca gcacatccac ctgcttttgt gcctctacat aggctgcgaa
    67741 atccgccatc accagatacg gatcgccgcc ctgtttgccg atactgtgca gcatctggtc
    67801 gaaggcatgc ttatcgccgt cgctgtattt accgctttcc agctctttca atactgcgtc
    67861 cagcacctta tctttcttcc gccatttcac cgggtcgtag cctttggcca gaattgcctt
    67921 cacttgttcc acggtatgac caaaaataaa gatattttct tcaccgactt tctcggcgat
    67981 ttcaacgttc gccccatcca gcgtaccgac agtaagcgca ccattgagcg ccagtttcat
    68041 attgccggta ccggaagctt ctttacctgc agtcgaaatt tgttcggaga tatccgccgc
    68101 cgggatcagt ttttccgccg ccgaaacgca ataatccggc aggaacacca ccttcaactt
    68161 atcgccaacc agcggatcgt tgttgatcac gtcagccact ttgttgatcg caaagataat
    68221 attcttcgcc aggtagtagc ccggtgccgc tttcgcgccg aagaggaaga cgcgcggtac
    68281 gcgatcagcc tgcgggtttt cacgaatttc tttgtacaac gccagaatat gcagcagatt
    68341 caggtgctgg cgtttgtact catgcaaacg tttgatctga atatcgaaaa tcgcctgtgg
    68401 attgatctca ataccggtac gaactttcac aaactccgcc agacggactt tattcgcctg
    68461 cttgatctcg cgatattgct gacggaattt cgcatcatca gcgaattttt ccagattgat
    68521 cagctgatcg agatcgttag cccactcttt ttgcagtgat ttatccaaca gagccgccag
    68581 tgccgggttg cactgtttga tccagcgacg tggggtaata ccgttggtga cgttatggaa
    68641 tttgttcggc catagctggt gatattccgg gaacagatct ttcaccacca gatccgagtg
    68701 cagcgccgca acaccgttca ccgcgaaacc gccaaccaca cacaggttcg ccatatgcac
    68761 ttgtttgtcg tgcaccaccg ccagtttggc ccacactttt tcatcgcccg gccaggtttt
    68821 ctctaccagc gttttaaagc gagtattaat ttcgttaata atctgcatgt ggcgcggcag
    68881 taagcctttc accagtttca catcccagcg ttccagcgct tctggcatca gggtatggtt
    68941 ggtgtaagcg aaagttttgc tggtaatggc ccaggcgtca tcccagctca tctggtgctc
    69001 atcgatcagc acgcgcagca gttctggaat cgcgatagtt gggtgggtat cgttcagctg
    69061 aataacttcg taatccgcca gttcgtgcag tttacgcccc gccagatgat ggcgacgcaa
    69121 aatatccgct accgaacagg cacactggaa gtattgctgc atcaggcgca gctttttacc
    69181 ggcagtatgg ttgtcgtttg gatagagaac tttggtcagt ttttccgcat tgatgccctg
    69241 ctgttcggca cgcaagaaat caccgtcgtt aaatttagtc agatcaaacg gatgcgcgtg
    69301 cgtcgcctgc cacagacgca gcggctgcgc cacgccatta cgatagccga caacggggag
    69361 atcccacgct tgaccggtaa tggtaaactc cggctcccag cgtccgtctt tcgtcacttt
    69421 accgccaatc cctacctgca catccagtgc ttcgttgtgg cggaaccacg ggtagttact
    69481 gcgatgccag tcatccggcg cttcaacctg tttgccatcg acaaaagact ggcggaacaa
    69541 accatattga tagttcagac cgtaacccgt cgcagactga ccgacagttg ccattgagtc
    69601 gaggaagcac gccgccagac gtcccagacc accgttaccc agcgccgggt cgatctcttc
    69661 ttccagcagg tccgtcagat tgatgtcata agccttcaac gaatcctgta catcctgata
    69721 ccagccgaga ttcaacaggt tgttgcccgt caggcgacca atcaaaaact ccattgagat
    69781 gtagttaaca tgtcgctgat tcgccaccgg cttggcgaat ggctgagcac gcagcatttc
    69841 ggccagtgct tcactcactg ctagccacca ctggcgagga gtcatttcag ccgcagaatt
    69901 taagccataa cgctgccact gacgtgaaag cgcttcctga aattgcttat cgttaaaaat
    69961 aggttgtgac ataggagttc cacttttctt agattttcaa cacaacgtta tcgctagttt
    70021 gccaggctcg atgttgacct tcctcatcct gcgggggatt aggcagggag gagttgcggg
    70081 gatgagcaag gaaatgtgat ctcaaccact taaagctagt gcaaaccaca ggattagcat
    70141 caaatcaatg caatacagcg cagaaaatct gtatctaagt gcaaaaaatg gccgttgcgt
    70201 attttcaaaa agcggaaggt aactctataa attaagtaaa ggagtgaaac agtttcataa
    70261 gtaaaatatc cagtgtgctc catctcattc ttaatagatt tattaagatc atctttttag
    70321 atggcacttt catcaggaat gaagaagaaa cccttgctta aatgaatctg atgaacataa
    70381 gggaaaccag tattcacgct ggatcagcgt cgttttaggt gagttgttaa taaagatttg
    70441 gaattgtgac acagtgcaaa ttcagacaca taaaaaaacg tcatcgcttg cattagaaag
    70501 gtttctggcc gaccttataa ccattaatta cgaagcgcaa aaaaaataat atttcctcat
    70561 tttccacagt gaagtgatta actatgctga ttccgtcaaa actaagtcgt ccggttcgac
    70621 tcgaccatac cgtggttcgt gagcgcctgc tggctaaact ttccggcgcg aacaacttcc
    70681 ggctggcgct gatcacgagt cctgcgggct acggaaagac caccctcatt tcccagtggg
    70741 cggcaggcaa aaacgatatc ggctggtact cgctggatga aggtgataac cagcaagagc
    70801 gtttcgccag ctatctcatt gccgccgtgc agcaggcaac caacggtcac tgtgcgatat
    70861 gtgagacgat ggcgcaaaaa cggcaatatg ccagcctgac gtcactcttc gcccagcttt
    70921 tcattgagct ggcggaatgg catagcccac tttatctggt catcgatgac tatcatctga
    70981 tcactaatcc agtgatccac gagtcaatgc gcttctttat tcgccatcaa ccagaaaatc
    71041 tcaccctggt ggtgttgtca cgcaaccttc cgcaactggg cattgccaat ctgcgtgttc
    71101 gtgatcaact gctggaaatt ggcagtcagc aactggcatt tacccatcag gaagcgaagc
    71161 agttttttga ttgccgtctg tcatcgccga ttgaagccgc agaaagcagt cggatttgcg
    71221 atgacgtttc cggttgggcg acggcactac agctaatcgc cctctccgcc cggcagaata
    71281 cccactcagc ccataagtcg gcacgccgcc tggcgggaat caatgccagc catctttcgg
    71341 attatctggt cgatgaggtt ttggataacg tcgatctcgc aacgcgccat tttctgttga
    71401 aaagcgccat tttgcgctca atgaacgatg ccctcatcac ccgtgtgacc ggcgaagaaa
    71461 acgggcaaat gcgcctcgaa gagattgagc gtcaggggct gtttttacag cggatggatg
    71521 ataccggcga gtggttctgc tatcacccgc tgtttggtaa cttcctgcgc cagcgctgcc
    71581 agtgggaact ggcggcggag ctgccggaaa tccaccgtgc cgccgcagaa agctggatgg
    71641 cccagggatt tcccagcgaa gcgattcatc atgcgctggc ggcaggcgat gcgctgatgc
    71701 tgcgcgatat tctgcttaat cacgcctgga gtctgttcaa ccatagcgaa ctgtcgctgc
    71761 tggaagagtc gcttaaggcc ctgccgtggg acagcttgct ggaaaatccg cagttggtgt
    71821 tattgcaggc gtggctgatg caaagccaac atcgctacgg cgaagttaac accctgctag
    71881 cccgtgctga acatgaaatc aaggacatca gagaagacac catgcacgca gaatttaacg
    71941 ctctgcgcgc ccaggtggcg attaacgatg gtaatccgga tgaagcggaa cggctggcaa
    72001 aactggcact ggaagagctg ccgccgggct ggttctatag ccgcattgtg gcaacctcgg
    72061 tgctgggtga agtgctgcac tgcaaaggcg aattgacccg ctcactggcg ctaatgcagc
    72121 aaaccgaaca gatggcacgc cagcacgatg tctggcacta cgctttgtgg agtttaatcc
    72181 agcaaagtga aattctgttt gcccaagggt tcctgcaaac cgcgtgggaa acgcaggaaa
    72241 aagcattcca gctgatcaac gagcagcatc tggaacagct gccaatgcat gagtttctgg
    72301 tgcgcattcg tgcgcagctg ttatgggcct gggcgcggct ggatgaagcc gaagcgtcgg
    72361 cgcgtagcgg gattgaagtc ttgtcgtctt atcagccaca gcaacagctt cagtgcctgg
    72421 caatgttgat tcaatgctcg ctggcccgtg gtgatttaga taacgcccgt agccagctga
    72481 accgtctgga aaacctgctg gggaatggca aatatcacag cgactggatc tctaacgcca
    72541 acaaagtccg ggtgatttac tggcaaatga ccggcgataa agccgccgct gccaactggt
    72601 tgcgtcatac ggctaaacca gagtttgcga acaaccactt cctgcaaggt caatggcgca
    72661 acattgcccg tgcacaaatc ttgctgggcg agtttgaacc ggcagaaatt gttctcgaag
    72721 aactcaatga aaatgcccgg agtctgcggt tgatgagcga tctcaaccgt aacctgttgc
    72781 tgcttaatca actgtactgg caggccggac gtaaaagtga cgcccagcgc gtgttgctgg
    72841 acgcattaaa actggcgaat cgcaccggat ttatcagcca ttttgtcatc gaaggcgaag
    72901 cgatggcgca acaactgcgt cagctgattc agcttaatac gctgccggaa ctggaacagc
    72961 atcgcgcgca gcgtattctg cgagaaatca atcaacatca tcggcataaa ttcgcccatt
    73021 tcgatgagaa tttcgttgaa cgtctgctaa atcatcctga agtacctgaa ctgatccgca
    73081 ccagcccgct gacgcaacgt gaatggcagg tactggggct gatctactct ggttacagca
    73141 atgagcaaat tgccggagaa ctggaagtcg cggcaaccac catcaaaacg catatccgca
    73201 atctgtatca gaaactcggc gtggcccatc gccaggatgc ggtacaacac gcccagcaat
    73261 tgctgaagat gatggggtac ggcgtgtaag tttagccgga taacgcgcca gatccggctt
    73321 acatctctgc atcattcaat gctcacccgc gttacgccat ctgtttctat caaactaaac
    73381 cgcaccggca agaaacgctc caccaccgcg atattggtca gcagatggca tgagggatgg
    73441 gcgaccgtaa attcccccgc gcccgccagc gccatcggta gcaccagttg gtcagcaaga
    73501 tattccccca ccgccgccgt gcttgccagg tagcgtttca cctctttcac caactgtgcc
    73561 gcaaccacct cggcactgac gcgcttttca ccgacgacaa aaaagcgttc ggtgatattt
    73621 tcactttcga cttcaagcga gacggtatta cccggcccct ggtcgcgcgg caggttatga
    73681 atattctgtt catgcaggga aaaactcccc gccagtgtag cgatttcacg ctcagcaaca
    73741 tggcgcggca caccagctaa tagaacttct ccacgcatct gcacaatgtt cccgcgctcg
    73801 ccaagttgca aggtgttaaa cgatgccacg ggcgagactt ccgttgccac cacaccgcct
    73861 ccggcagggt aaaaaccgtg gcgtaacagc gtggtttgct gatgaattcc tattttcgcc
    73921 agcagcggct ccagcacccg gcggataaaa tccgcaggcg gcgccgacgg gttatcggtg
    73981 ccgccgctca cttcaacacg cgaaggtcca tcggcaaacc acagcgcggg cagcaccgtt
    74041 tgcagcacca gcgtacaact tccggcgcta ccgatagcaa agcggtaatc gccgccgcgc
    74101 acggtgccgg gccggaagag cagacgctgc gaccccagct ccgcgccttc cacggttgct
    74161 ccgcaaattt ccgtcgccgc ctttaccgcg gtcagatgct ggcgcaacag ccccggtttc
    74221 gcccgcccgg cacgaatgct ggtgatggta aatggctggc cggttatcat cgacaggctc
    74281 agcgccgagc gcaggatctg cccgccacct tcgccctgtg cgccatccag cgcaatcatc
    74341 cttttcatca tttatccttt tacgcacacc acctgacgca gggtatagat aacttccacc
    74401 agatcgcttt gtgccgccat caccgcatca atatctttat acgccatcgg gatttcgtcg
    74461 atcacttcgg catctttacg gcattccaca tgcgcggtgg cacgaatttg atcttccacg
    74521 ctgaacagtt ttttcgcttt agttcggctc attacccgcc cggcaccgtg gctgcacgaa
    74581 cagaacgact cttcatttcc cagcccacgg acgataaagc tttttgctcc catcgaaccg
    74641 ggaataattc catattgacc agcacgcgca gacaccgcgc ctttacgcgt cacgtagatc
    74701 tcttcaccaa agtgctgttc tttttgcaca tagttgtggt gacagttgat ctcttccatc
    74761 gccagcgttt gtggctgtct gaccgttttc tgcgtaatgc tctgcaatgc cgttaccacg
    74821 ttttccatca tcgcatcgcg gttaaggctg gcaaaaagct gcgcccaggc cacggctttc
    74881 aggtaatcat caaagtattc cgtaccttcc ataaagtacg ccagatcacg cgacggcaac
    74941 gtctcaagcg tttcctgcat ctctttttgt gccagatcga taaagtaagt cccgatggcg
    75001 ttaccaattc cgcgtgaacc ggagtgcagc ataatccaca cctggtccga ctcatcaagg
    75061 cagatttcaa taaagtggtt accggttccc agcgttccca ggtgtttata gttattggta
    75121 ttcaggaaac ggggatattt ttgcgttaac cactgataac cggcttcaag ctcagcccat
    75181 ttagcatcga cgttaacagg tggattttcc caggcacctt tatcacgttt acaacggcca
    75241 gtggtacgcc cgtgcggcac ggccgtttca atcgcctgac gcagctctgc caggttttca
    75301 ggcaggtctt ccgccgttaa cgcggtacgc agcgcgttca ttccacagcc aatatccacg
    75361 cccaccgccg ccggaataat cgcccctttg gtcgggatca cgctaccaat ggtggaacct
    75421 ttacccaggt gtacatcagg cattaccgca atatgtttga aaataaacgg catcttcgcc
    75481 gtattaataa gttgctgacg cgcatcggcc tctaccggca cgcctttggt ccacattttt
    75541 accggggcat tttcagtggt cagtaattcg taattc
//
LOCUS       DACAOP010000010        72665 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.010, whole genome shotgun sequence.
ACCESSION   DACAOP010000010 DACAOP010000000
VERSION     DACAOP010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 72665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72665
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.010"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(189..265)
                     /locus_tag="IT892_000745"
     tRNA            complement(189..265)
                     /locus_tag="IT892_000745"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(229..231),aa:Arg,seq:acg)
     gene            complement(269..361)
                     /locus_tag="IT892_000746"
     tRNA            complement(269..361)
                     /locus_tag="IT892_000746"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Ser,seq:gct)
     gene            complement(677..862)
                     /gene="csrA"
                     /locus_tag="IT892_000747"
     CDS             complement(677..862)
                     /gene="csrA"
                     /locus_tag="IT892_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HAP3133987.1"
                     /translation="MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHR
                     EEIYQRIQAEKSQQSSY"
     gene            complement(1097..3727)
                     /gene="alaS"
                     /locus_tag="IT892_000748"
     CDS             complement(1097..3727)
                     /gene="alaS"
                     /locus_tag="IT892_000748"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAP3133988.1"
                     /translation="MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGM
                     NQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDY
                     FKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDN
                     KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQ
                     FNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDL
                     SNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKL
                     VGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDG
                     ETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMI
                     RVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGD
                     KGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSA
                     THLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNL
                     PIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRI
                     ISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTR
                     QLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLG
                     STIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTD
                     AAALPAALASVKGWVSAKLQ"
     gene            complement(3856..4356)
                     /gene="recX"
                     /locus_tag="IT892_000749"
     CDS             complement(3856..4356)
                     /gene="recX"
                     /locus_tag="IT892_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAP3133989.1"
                     /translation="MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKN
                     GPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGIS
                     REATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDI
                     WRNFAD"
     gene            complement(4425..5486)
                     /gene="recA"
                     /locus_tag="IT892_000750"
     CDS             complement(4425..5486)
                     /gene="recA"
                     /locus_tag="IT892_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAP3133990.1"
                     /translation="MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTG
                     SLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDP
                     IYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
                     GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKF
                     YASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
                     DLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNS
                     TPDFSVDDSEGVAETNEDF"
     gene            complement(5566..6063)
                     /gene="pncC"
                     /locus_tag="IT892_000751"
     CDS             complement(5566..6063)
                     /gene="pncC"
                     /locus_tag="IT892_000751"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HAP3133991.1"
                     /translation="MTDSELMQLSEQVGQALKARGATVTTAESCTGGWVAKVITDIAG
                     SSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSEPVVVEMAIGALKAARADYAVSI
                     SGIAGPDGGSEEKPVGTVWFAFATARGEGITRRECFSGDRDAVRRQATAYALQTLWQQ
                     FLQNT"
     gene            complement(6208..7293)
                     /gene="mltB"
                     /locus_tag="IT892_000752"
     CDS             complement(6208..7293)
                     /gene="mltB"
                     /locus_tag="IT892_000752"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HAP3133992.1"
                     /translation="MFKRRYVTLLPLFVLLAACSSKPKPTETETTTGTPSGGFLLEPQ
                     HNVMQMGGDFANNPNAQQFIDKMVNKHGFDRQQLQEILSQAKRLDSVLRLMDNQAPTT
                     SVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIG
                     VETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFA
                     GAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMAN
                     GQAPGLPNGFKTKYSISQLTAAGLTPQQPLGNHQQASLLRLDVGTGYQYWYGLPNFYT
                     ITRYNHSTHYAMAVWQLGQAVALARVQ"
     gene            7549..8112
                     /gene="srlA"
                     /locus_tag="IT892_000753"
                     /gene_synonym="gutA"
     CDS             7549..8112
                     /gene="srlA"
                     /locus_tag="IT892_000753"
                     /gene_synonym="gutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAP3133993.1"
                     /translation="MIETITHGAEWFIGLFQKGGEVFTGMVTGILPLLISLLVIMNAL
                     INFIGQHRIERFAQRCAGNPVSRYLLLPCIGTFVFCNPMTLSLGRFMPEKYKPSYYAA
                     ASYSCHSMNGLFPHINPGELFVYLGIASGLTTLNLPLGPLAVSYLLVGLVTNFFRGWV
                     TDLTTAIFEKKMGIQLEQKVHLAGATS"
     gene            8109..9068
                     /gene="srlE"
                     /locus_tag="IT892_000754"
                     /gene_synonym="gutE"
     CDS             8109..9068
                     /gene="srlE"
                     /locus_tag="IT892_000754"
                     /gene_synonym="gutE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAP3133994.1"
                     /translation="MTRIRIEKGTGGWGGPLELEATPGKKIVYITAGTRPAIVDKLAQ
                     LTGWQAIDGFKEGEPAEAEIGVAVIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLEQY
                     IVEDIYVSGVKEENITVVGDATPQPSSVGRDYDTSKKITEQSDGLLAKVGMGMGSAVA
                     VLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGLVMLA
                     LICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACDFIPV
                     GLSLAEARQDTVRVGVPSVLVSRFLTGAPTVLIAWFVSGFIYQ"
     gene            9079..9450
                     /gene="srlB"
                     /locus_tag="IT892_000755"
                     /gene_synonym="gutB"
     CDS             9079..9450
                     /gene="srlB"
                     /locus_tag="IT892_000755"
                     /gene_synonym="gutB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP3133995.1"
                     /translation="MTVIYQTTITRIGASATDALSDQMLITFREGAPADLEEYCFIHC
                     HGELKGALHPGLQFSLGQHRYPVTAVGSVAEDNLRELGHVTLRFDGLNEAEFPGTVHV
                     AGPVPDDIAPGSVLKFESVKE"
     gene            9454..10233
                     /gene="srlD"
                     /locus_tag="IT892_000756"
     CDS             9454..10233
                     /gene="srlD"
                     /locus_tag="IT892_000756"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HAP3133996.1"
                     /translation="MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQ
                     EINAEYGEGMAYGFGADATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQL
                     GDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
                     GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPDQVEQYYIDK
                     VPLKRGCDYQDVLNMLLFYASPKASYCTGQSINVTGGQVMF"
     gene            10339..10698
                     /gene="gutM"
                     /locus_tag="IT892_000757"
     CDS             10339..10698
                     /gene="gutM"
                     /locus_tag="IT892_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HAP3133997.1"
                     /translation="MVSALITVAVIAWCAQLALGGWQISRFNRAFDTLCQQGRVGVGR
                     SSGRFKPRVVVVIALDDQQRIVDTLFMKGLTVFARPQKIPAITGMYAGDLQPDVIFPN
                     DPLSQNALSLALKLKRG"
     gene            10765..11538
                     /gene="srlR"
                     /locus_tag="IT892_000758"
                     /gene_synonym="gutR"
     CDS             10765..11538
                     /gene="srlR"
                     /locus_tag="IT892_000758"
                     /gene_synonym="gutR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol operon DNA-binding transcriptional
                     repressor SrlR"
                     /protein_id="HAP3133998.1"
                     /translation="MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILE
                     HAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIILDAGST
                     VLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
                     FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNV
                     VCSLESVDKLITDAGIDPAFRQALEKKGIDVIITGESNE"
     gene            11531..12496
                     /gene="gutQ"
                     /locus_tag="IT892_000759"
     CDS             11531..12496
                     /gene="gutQ"
                     /locus_tag="IT892_000759"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase GutQ"
                     /protein_id="HAP3133999.1"
                     /translation="MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGK
                     VVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGA
                     KELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
                     LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASV
                     MDAMLELSRTGLGLVAVCDAQQQVQGVFTDGDLRRWLVGGGALTTPVNEAMTTGGTTL
                     QAQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII"
     gene            complement(12493..14007)
                     /gene="norR"
                     /locus_tag="IT892_000760"
     CDS             complement(12493..14007)
                     /gene="norR"
                     /locus_tag="IT892_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311592.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase transcriptional regulator
                     NorR"
                     /protein_id="HAP3134000.1"
                     /translation="MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALL
                     RYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLI
                     PGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
                     LLIEQLESQNMLPGDATPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETG
                     TGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFE
                     MADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREE
                     VLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGAR
                     NLLQHYSFPGNVRELEHAIHRAVVLSRATRSGDEVILEAQHFAFPEVTLPPPEAAAVP
                     VVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD"
     gene            14194..15633
                     /gene="norV"
                     /locus_tag="IT892_000761"
     CDS             14194..15633
                     /gene="norV"
                     /locus_tag="IT892_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic nitric oxide reductase
                     flavorubredoxin"
                     /protein_id="HAP3134001.1"
                     /translation="MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEK
                     NVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYC
                     TANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDA
                     VLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNL
                     PVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGI
                     AETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLR
                     FRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREI
                     ARQWALAPLPQSTVNTVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGT
                     PWSEVPDNFLCPECSLGKDVFDELASEEK"
     gene            15630..16763
                     /gene="norW"
                     /locus_tag="IT892_000762"
     CDS             15630..16763
                     /gene="norW"
                     /locus_tag="IT892_000762"
                     /EC_number="1.18.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavorubredoxin reductase NorW"
                     /protein_id="HAP3134002.1"
                     /translation="MSNGIVIIGSGFAARQLVKNIRKQDASIPLTLIAADSMDEYNKP
                     DLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTWVTDIDAEAHVVKSQNNQWQYDK
                     LVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
                     CRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILA
                     TLDRQRSIEVDTVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCAE
                     INGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLR
                     WQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPV"
     gene            complement(16841..19081)
                     /gene="hypF"
                     /locus_tag="IT892_000763"
     CDS             complement(16841..19081)
                     /gene="hypF"
                     /locus_tag="IT892_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HAP3134003.1"
                     /translation="MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGD
                     GVEVRLLEDPETFLVQLHQHCPPLARIDSVEREPFIWSQLPTEFTIRQSAGGVMNTQI
                     VPDAATCPACLAEMNTPGERRWRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCP
                     ACDKEYRDPLDRRFHAQPVACPECGPHLEWISHGEHAEQEAALQAAIAQLKMGNIVAI
                     KGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVAEGLPDAARQLLTTPAAPIV
                     LVDKKYVPELCDDIAPGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISN
                     EQALADLQGIADGFLLHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALALPPGFKNVP
                     PVLCLGADLKNTFCLVRGEQAVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTPQYVV
                     HDVHPGYVSSQWAREMNLPTQTMLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGE
                     NGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAKQPWRNLLAQCLRFVPEWQNYPE
                     TASVQQQNWSVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEA
                     LAASCDGVTHPVTMPLVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMRE
                     QATMRGITTLVFSGGVIHNRLLRTRLSHYLADFTLLFPQSLPAGDGGLSLGQGVIAAA
                     RILHTA"
     gene            complement(19234..19761)
                     /gene="hydN"
                     /locus_tag="IT892_000764"
     CDS             complement(19234..19761)
                     /gene="hydN"
                     /locus_tag="IT892_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport protein HydN"
                     /protein_id="HAP3134004.1"
                     /translation="MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRI
                     HVIKGVNISTATVCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYG
                     AMEVVVRPVIRNSGAGLNVRADKAEANKCDLCNHREDGPACMAACPTHALICVDRNKL
                     EQLSAEKRRRTALMF"
     gene            complement(19910..20923)
                     /locus_tag="IT892_000765"
     CDS             complement(19910..20923)
                     /locus_tag="IT892_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311597.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP3134005.1"
                     /translation="MMTTMLEVAKRAGVSKATVSRVLSGNGYVSQETKDRVFQAVEES
                     GYRPNLLARNLSAKSTQTLGLVVTNTLYHGIYFSELLFHAARMAEEKGRQLLLADGKH
                     SAEEERQAIQYLLDLRCDAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRKNSSHSV
                     WCDHKQTSFNAVAELINAGHQEIAFLTGSMDSPTSVERLAGYKDALAQHGIALNEKLI
                     ANGKWTPASGAEGVETLLERGAKFSALVASNDDMAIGAMKALHERGVAVPEQVSVIGF
                     DDIAIAPYTVPALSSVKIPVTEMIQEIIGRLIFMLDGGDFSPPKTFSGKLIRRGSLIA
                     LSQ"
     gene            21180..22637
                     /gene="ascF"
                     /locus_tag="IT892_000766"
     CDS             21180..22637
                     /gene="ascF"
                     /locus_tag="IT892_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose/arbutin/salicin transporter
                     subunit IIBC"
                     /protein_id="HAP3134006.1"
                     /translation="MAKNYAALARSVIAALGGVNNISAVTHCMTRLRFVIKDDQLIDS
                     PTLKTISGVLGVVRSDNQCQVIIGNTVSQAFQEVVSLLPGDMQPAQPVGKPKLTLRRI
                     GAGILDALIGTMSPLIPAIIGGSMVKLLAMILEMSGVLTKGSPTLTILNVIGDGAFFF
                     LPLMVAASAAIKFKTNMSLAIAIAGVLVHPSFIELMAKAAQGEHVEFALIPVTAVKYT
                     YTVIPALVMTWCLSYIERWVDSITPAVTKNFLKPMLIVLIAAPLAILLIGPIGIWIGS
                     AISALVYTIHGYLGWLSVAIMGALWPLLVMTGMHRVFTPTIIQTIAETGKEGMVMPSE
                     IGANLSLGGSSLAVAWKTKNPELRQTALAAAASAIMAGISEPALYGVAIRLKRPLIAS
                     LISGFICGAVAGMAGLASHSMAAPGLFTSVQFFEPANPMSIVWVFAVMALAVVLSFIL
                     TLLLGFEDIPVEEATAEARKHQSAQPTVAKEVSLN"
     gene            22646..24070
                     /locus_tag="IT892_000767"
     CDS             22646..24070
                     /locus_tag="IT892_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP3134007.1"
                     /translation="MSVFPEGFLWGGALAANQSEGAYREGGKGLTTVDMIPHGEHRMA
                     VKLGLEKRFQLRDDEFYPSHEATDFYHRYKEDIALMAEMGFKVFRTSIAWSRLFPQGD
                     ELTPNQQGIAFYRAVFEECKKYGIEPLVTLCHFDVPMHLVTEYGSWRNRKLVEFFSRY
                     ARTCFEAFDGLVKYWLTFNEINIMLHSPFSGAGLVFEEGENQDQVKYQAAHHQLIASA
                     LATKIAHEVNPQNQVGCMLAGGNFYPYSCKPEDVWAALEKDRENLFFIDVQARGAYPA
                     YSARVFREKGVTIDKAPGDDEILKNTVDFVSFSYYASRCASAEMNANNSSAANVVKSL
                     RNPYLQVSDWGWGIDPLGLRITMNMMYDRYQKPLFLVENGLGAKDEFAANGEINDDYR
                     ISYLREHIRAMGEAIADGIPLMGYTTWGCIDLVSASTGEMSKRYGFVFVDRDDAGNGT
                     LTRTRKKSFWWYKKVIASNGEDLE"
     gene            complement(24149..24568)
                     /locus_tag="IT892_000768"
     CDS             complement(24149..24568)
                     /locus_tag="IT892_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP3134008.1"
                     /translation="MTANAARAVKATRELVNAVPFLGGSDSEDDYREALELVEYLIEE
                     DDTNPLIDFLASRIAEYENNNEKFAEFDKAVAAMPVGVALLRTLIDQHNLTYADLKNE
                     IGSKSLVSQILSGQRSLTISHIKALSARFGVKPEWFL"
     gene            complement(24565..24876)
                     /locus_tag="IT892_000769"
     CDS             complement(24565..24876)
                     /locus_tag="IT892_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HAP3134009.1"
                     /translation="MHIISKAPFEECARKYPNDALALYSLYRVIKETDFSTPEEMRTA
                     FPNLDNFRYRNKWYVLDVGGNNLRVIAYINFVNKRFFVKHITNHAEYDKLTRYYRENK
                     E"
     gene            complement(25043..25513)
                     /gene="hycI"
                     /locus_tag="IT892_000770"
     CDS             complement(25043..25513)
                     /gene="hycI"
                     /locus_tag="IT892_000770"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HAP3134010.1"
                     /translation="MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPE
                     NDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPDDIAEMFMMTTHNMPLNYLIDQLK
                     EDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWEGNGGFAQLAVEEE"
     gene            complement(25506..25916)
                     /locus_tag="IT892_000771"
     CDS             complement(25506..25916)
                     /locus_tag="IT892_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HycH family protein"
                     /protein_id="HAP3134011.1"
                     /translation="MSEKVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDC
                     LEAALTCPWDEYLAWIATLEAGSEARRKMEGVPKYGEIVIDINHVPMLANAFDKARAA
                     QTSQQKEWSTMLLSMLHDIHQENAIYLMVRRLRD"
     gene            complement(25913..26680)
                     /gene="hycG"
                     /locus_tag="IT892_000772"
     CDS             complement(25913..26680)
                     /gene="hycG"
                     /locus_tag="IT892_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycG"
                     /protein_id="HAP3134012.1"
                     /translation="MSNLLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVD
                     CGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQS
                     APDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMAL
                     GLLEQKIHARGPGEQDEQPAEILHGDMVQPLRVKVDREARRLAGYRYGRQIADDFLTQ
                     LGQGEEQVARWLEAENDPRLNEIVSHLNHVVEEARIR"
     gene            complement(26680..27222)
                     /gene="hycF"
                     /locus_tag="IT892_000773"
     CDS             complement(26680..27222)
                     /gene="hycF"
                     /locus_tag="IT892_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycF"
                     /protein_id="HAP3134013.1"
                     /translation="MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEQNPQQCIGCA
                     ACVNACPSNALTVETDLATGELAWEFNLGRCIFCGRCEEVCPTAAIKLSQEYELAVWK
                     KEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR
                     QKCLVPSDRIELTRHMKEAI"
     gene            complement(27232..28941)
                     /locus_tag="IT892_000774"
     CDS             complement(27232..28941)
                     /locus_tag="IT892_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase large subunit"
                     /protein_id="HAP3134014.1"
                     /translation="MSEEKLGQHYLAALNEAFPGVVLDHAWQTKDQLTVTVKVNYLPE
                     VVEFLYYKQGGWLSVLFGNDERKLNGHYAVYYVLSMEKGTKCWITVRVEVDANKPEYP
                     SVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSMDYRQRPA
                     PTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHR
                     GMEKLAETRMGYNEVTFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILL
                     EVERLHSHLLNLGLASHFTGFDSGFMQFFRVRETSMKMAEILTGARKTYGLNLIGGIR
                     RDLLKDDMIQTRQLAQQMRREVQELVDVLLSTPNMEQRTVGIGRLDPEIARDFSNVGP
                     MVRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTALNMIDYGLD
                     NLPGGPLMVEGFTYIPHRFALGFAEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPT
                     LRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPYKELERYSIERKNS
                     PLK"
     gene            complement(28959..29882)
                     /gene="hycD"
                     /locus_tag="IT892_000775"
     CDS             complement(28959..29882)
                     /gene="hycD"
                     /locus_tag="IT892_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycD"
                     /protein_id="HAP3134015.1"
                     /translation="MSVLYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYR
                     DIIKLLGRQSVGPDASGWVFRLTPYVMVGVMLTIATALPVVTVGSPLPQLGDLITLLY
                     LFAIARFFFAISGLDTGSPFTAIGASREAMLGVLVEPMLLLGLWVAAQVAGSTNISNI
                     TDTVYHWPLSQSIPLVLALCACAFATFIEMGKLPFDLAEAEQELQEGPLSEYSGSGFG
                     VMKWGISLKQLVVLQMFVGVFIPWGQMETFTVGGLLLALVIAIVKLVVGVLVIALFEN
                     SMARLRLDITPRITWAGFGFAFLAFVSLLAA"
     gene            complement(29885..31711)
                     /gene="hycC"
                     /locus_tag="IT892_000776"
     CDS             complement(29885..31711)
                     /gene="hycC"
                     /locus_tag="IT892_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit 3"
                     /protein_id="HAP3134016.1"
                     /translation="MSAISLINSGVAWFVAAAVLAFLFSFQKALSGWIAGIGGAVGSL
                     YTAAAGFTVLTGAVGVSGALSLVSYDVQISPLNAIWLITLGLCGLFVSLYNIDWHRHA
                     QVKCNGLQINMLMAAAVCAVIASNLGMFVVMAEIMALCAVFLTNNSKEGKLWFALGRL
                     GTLLLAIACWLLWQRYGTLDLRLLDMRMQQLPLGSDIWLLGVIGFGLLAGIIPLHGWV
                     PQAHANASAPAAALFSTVVMKIGLLGILTLSLLGGNAPLWWGIALLVLGMITAFVGGL
                     YALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALEQPALIALGLVGGLYHLLNHSL
                     FKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEW
                     VIYQSFFKLSNSGAFVARLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAEN
                     ATCAPLLMSVSVVALAICCVIGGVAAPWLLPMLSAAVPLPLEPANTTVSQPMITLLLI
                     ACPLLPFIIMAICKGDRLPSRSRGAAWVCGYDHEKSMVITAHGFAMPVKQAFAPVLKL
                     RKWLNPVSLVPGWQCEGSALLFRRMALVELAVLVVIIVSRGA"
     gene            complement(31708..32319)
                     /locus_tag="IT892_000777"
     CDS             complement(31708..32319)
                     /locus_tag="IT892_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAP3134017.1"
                     /translation="MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEK
                     ESAPQLCHHCEDAPCAVVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGS
                     RPLDIPANANTPKAPPAPPAPARVSTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCP
                     TKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK"
     gene            complement(32444..32905)
                     /gene="hycA"
                     /locus_tag="IT892_000778"
     CDS             complement(32444..32905)
                     /gene="hycA"
                     /locus_tag="IT892_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase regulator HycA"
                     /protein_id="HAP3134018.1"
                     /translation="MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHH
                     AMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYYVETKDGEDKQRIAQAQLSIDGM
                     IDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPAA"
     gene            33117..33467
                     /gene="hypA"
                     /locus_tag="IT892_000779"
     CDS             33117..33467
                     /gene="hypA"
                     /locus_tag="IT892_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HAP3134019.1"
                     /translation="MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSL
                     AFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVA
                     DDGLQIRRIEIDQE"
     gene            33471..34343
                     /gene="hypB"
                     /locus_tag="IT892_000780"
     CDS             33471..34343
                     /gene="hypB"
                     /locus_tag="IT892_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HAP3134020.1"
                     /translation="MCTTCGCGEGNLYIEGDEHNPHSAFRSAPFAPAARPKMKITGIK
                     TPEFTPSQTEEGDLHYGHGEAGTHAPGMSQRRMLEVEIDVLDKNNRLAERNRARFAAR
                     KQLVLNLVSSPGSGKTTLLTETLMRLKDSVPCAVIEGDQQTVNDAARIRATGTPAIQV
                     NTGKGCHLDAQMIADAAPRLPLDDNGILFIENVGNLVCPASFDLGEKHKVAVLSVTEG
                     EDKPLKYPHMFAAASLMLLNKVDLLPYLNFDVEKCIACAREVNPEIEIILISATSGEG
                     MDQWLNWLETQRCA"
     gene            34334..34606
                     /gene="hypC"
                     /locus_tag="IT892_000781"
     CDS             34334..34606
                     /gene="hypC"
                     /locus_tag="IT892_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 3 maturation protein HypC"
                     /protein_id="HAP3134021.1"
                     /translation="MCIGVPGQIRTIDGNQAKVDVCGIQRDVDLTLVGSCDENGQPRV
                     GQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPDVGALLYGEEK"
     gene            34606..35727
                     /gene="hypD"
                     /locus_tag="IT892_000782"
     CDS             34606..35727
                     /gene="hypD"
                     /locus_tag="IT892_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HAP3134022.1"
                     /translation="MRFVDEYRSPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGH
                     THAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRIDTCVEIASHPEVIFCTFGDAMRV
                     PGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
                     AKARDVQNFYFFCQHITLIPTLRSLLEEPDNGIDAFLAPGHVSMVIGTDAYNFIASDF
                     HRPLVVAGFEPLDLLQGVVMLVEQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCV
                     NGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPRARCGEVLTGKCKPH
                     QCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA"
     gene            35724..36734
                     /gene="hypE"
                     /locus_tag="IT892_000783"
     CDS             35724..36734
                     /gene="hypE"
                     /locus_tag="IT892_000783"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417210.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation carbamoyl dehydratase
                     HypE"
                     /protein_id="HAP3134023.1"
                     /translation="MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLA
                     QLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEE
                     GLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPANIHWG
                     AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKA
                     LRDATRGGVNAVVHEFAAACGCGIEISEAALPVKPAVRGVTELLGLDALNFANEGKLV
                     IAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
                     IC"
     gene            36808..38886
                     /gene="flhA"
                     /locus_tag="IT892_000784"
     CDS             36808..38886
                     /gene="flhA"
                     /locus_tag="IT892_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase transcriptional activator
                     FlhA"
                     /protein_id="HAP3134024.1"
                     /translation="MSYTPMSDLGQQGLFDITRTLLQQPDLASLCEALSQLVKRSALA
                     DNAAIVLWQAQTQRASYYASREKDTPIKYEDETVLAHGPVRSILSRPDTLHCSYEEFC
                     ETWPQLAAGGLYPKFGHYCLMPLAAEGHIFGGCEFIRYDDRPWSEKEFNRLQTFTQIV
                     SVVTEQIQSRVVNNVDYELLCRERDNFRILVAITNAVLSRLDMDELVSEVAKEIHYYF
                     DIDDISIVLRSHRKNKLNIYSTHYLDKQHPAHEQSEVDEAGTLTERVFKSKEMLLINL
                     HERDDLAPYERMLFDTWGNQIQTLCLLPLMSGNTMLGVLKLAQCEEKVFTTTNLSLLR
                     QIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVL
                     KQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDL
                     FGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSN
                     KIIQTDVRLIAATNRDLKKMVADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAF
                     TFKIARRLGRNIDSIPAETLRTLSNMEWPGNVRELENVIERAVLLTRGNVLQLSLPDI
                     ALPEPETPPAATVVAQEGEDEYQLIVRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMK
                     RLGIDKSALI"
     gene            38931..39359
                     /locus_tag="IT892_000785"
     CDS             38931..39359
                     /locus_tag="IT892_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013364999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HAP3134025.1"
                     /translation="MAVSARNQLTGTVSAVAMGAVNDEVELTLAGGAKLVAIVTHSSQ
                     QALGLAKGKEAIALIKAPWVTLATEGCGLKFSARNQFAGSVSTITEGAVNATVHIKTD
                     AGFEIVAVVTNESQDEMKLTTGSRVIALIKASAILIATKA"
     gene            complement(39398..39742)
                     /locus_tag="IT892_000786"
     CDS             complement(39398..39742)
                     /locus_tag="IT892_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide-stimulated promoter family
                     protein"
                     /protein_id="HAP3134026.1"
                     /translation="MSGKRISREKLTIKKMIDLYQAKCPQASAEPEHYDALFAYAQKR
                     LDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWAGPRMLWRHPILTVRHLIDDKRP
                     VPELPEKYRPKK"
     gene            complement(39819..39953)
                     /locus_tag="IT892_000787"
     CDS             complement(39819..39953)
                     /locus_tag="IT892_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134027.1"
                     /translation="MIPELIISGEEANGEFLMVIPGKMLFCSFCVMLMKQVRKIASVE
                     "
     gene            40029..42590
                     /gene="mutS"
                     /locus_tag="IT892_000788"
     CDS             40029..42590
                     /gene="mutS"
                     /locus_tag="IT892_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP3134028.1"
                     /translation="MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDA
                     KRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATS
                     KGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEP
                     ADRETMAAELQRTNPAELLYAENFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFG
                     TRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRN
                     LEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDF
                     TAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLENVDSAPVQA
                     LREKMGEFAELRDLLERAIIDTPPVLVRDGGVIAPGYNEELDEWRALADGATDYLERL
                     EVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKE
                     YEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLN
                     YTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYM
                     RQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILH
                     NATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKME
                     GVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELES
                     ISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV"
     gene            42696..43352
                     /gene="pphB"
                     /locus_tag="IT892_000789"
     CDS             42696..43352
                     /gene="pphB"
                     /locus_tag="IT892_000789"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HAP3134029.1"
                     /translation="MPSTRYQKINAHHYRYIWAVGDIHGDYQLLQSRLHQLSFFPETD
                     LLISVGDNIDRGPESLNVLRLLNQPWFTSVKGNHEAMALDAFETGDGNMWLASGGDWF
                     FELNETEQQEAINLLLKFHRLPHIIEITNDIIKYVIAHADYPGNEYLFGKEIAERELL
                     WPVDRVQKSLNGELQQINGADYFIFGHMMFDNIQTFANQIYIDTGSPKSGRLSFYKIK
                     "
     gene            complement(43403..44200)
                     /locus_tag="IT892_000790"
     CDS             complement(43403..44200)
                     /locus_tag="IT892_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP3134030.1"
                     /translation="MSAGQRKEQKLIPVERRQIILEMVAEKGIVSIAELTDRMNVSHM
                     TIRRDLQKLEQQGAVVLVSGGVQSPGRVAHEPSHQVKTALAMTQKAAIGKLAASLVQP
                     GSCIYLDAGTTTLAIAQHLIHMESLTVVTNDFVIADYLLDNSNCTIIHTGGAVCRENR
                     SCVGEAAATMLRSLMIDQAFISASSWSVRGISTPAEDKVTVKRAIASASRQRVLVCDA
                     TKYGQVATWLALPLSEFDQIITDDGLPESASRALAKQDLSLLVAKNE"
     gene            44366..45274
                     /locus_tag="IT892_000791"
     CDS             44366..45274
                     /locus_tag="IT892_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAP3134031.1"
                     /translation="MKTGSEFHVGIVGLGSMGMGAALSCVRAGLSTWGADLNSNACAT
                     LKEAGACGVSDNAATFAEKLDALLVLVVNAAQVKQVLFGETGVAQHLKPGTAVMVSST
                     IASADAQEIATALAGFDLEMLDAPVSGGAVKAANGEMTVMASGSNIAFERLAPVLEAV
                     AGKVYRIGAEPGLGSTVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTNAAG
                     NSWMFENRMRHVVDGDYTPHSAVDIFVKDLGLVADTAKALHFPLPLASTALNMFTSAS
                     NAGYGKEDDSAVIKIFSGITLPGAKS"
     gene            45271..46533
                     /locus_tag="IT892_000792"
     CDS             45271..46533
                     /locus_tag="IT892_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="four-carbon acid sugar kinase family protein"
                     /protein_id="HAP3134032.1"
                     /translation="MIKIGVIADDFTGATDIASFLVENGLPTVQINGVPTGKMPEAID
                     ALVISLKTRSCPVVEATQQSLAALSWLQQQGCKQIYFKYCSTFDSTAKGNIGPVTDAL
                     MDALDTPFTVFSPALPVNGRTVYQGYLFVMNQLLAESGMRHHPVNPMTDSYLPRLVEA
                     QSTGRCGVVSAHVFEQGVDAVRQELARLQQEGYRYAVLDALTEHHLEIQGEALRDTPL
                     VTGGSGLAIGLARQWAQENGNQARKAGHPLAGRGVVLSGSCSQMTNRQVAHYRQIAPA
                     REVDVARCLSIETLAAYAHELAEWVLGQESVLAPLVFATASTDALAAIQQQYGAHKAS
                     QAVETLFSQLAARLAAEGVTRFIVAGGETSGVVTQSLGIKGFHIGPTISPGVPWVNAL
                     DKPVSLALKSGNFGDEAFFSRAQREFLS"
     gene            46530..47168
                     /locus_tag="IT892_000793"
     CDS             46530..47168
                     /locus_tag="IT892_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAP3134033.1"
                     /translation="MSDFAKVEQSLREEMTRIASSFFQRGYATGSAGNLSLLLPDGNL
                     LATPTGSCLGNLDPQRLSKVAADGEWLSGDKPSKEVLFHLALYRNNPRCKAVVHLHST
                     WSTALSCLQGLDSSNVIRPFTPYVVMRMGNVPLVPYYRPGDKRIAQDLAELAADNQAF
                     LLANHGPVVCGESLQEAANNMEELEETAKLIFILGDRPIRYLTAGEIAELRS"
     gene            47173..47949
                     /locus_tag="IT892_000794"
     CDS             47173..47949
                     /locus_tag="IT892_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HAP3134034.1"
                     /translation="MPRFAANLSMMFTEVPFIERFAAARKAGFDAVEFLFPYDYSTLQ
                     IQKQLEQNHLTLALFNTAPGDINAGEWGLSALPGREHEAHADIDLALEYALALNCEQV
                     HVMAGVVPAGEDAERYRAVFIDNLRYAADRFAPHGKRILVEALSPGVKPHYLFSSQYQ
                     ALAIVEEVARDNVFIQLDTFHAQKVDGNLTHLIRDYAGKYAHVQIAGLPDRHEPDDGE
                     INYPWLFRLFDEVGYQGWIGCEYKPRGLTEEGLGWFDAWR"
     gene            48038..49402
                     /locus_tag="IT892_000795"
     CDS             48038..49402
                     /locus_tag="IT892_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family transporter"
                     /protein_id="HAP3134035.1"
                     /translation="MSTITLLCIALTGVIMLLLLVIKAKVQPFVALLLVSLLVALAAG
                     IPAGEVGKVMIAGMGGVLGSVTIIIGLGAMLGRMIEHSGGAESLANYFSRKLGDKRTI
                     AALTLAAFFLGIPVFFDVGFIILAPIIYGFAKVAKISPLKFGLPVAGIMLTVHVAVPP
                     HPGPVAAAGLLHADIGWLTIIGIAISIPVGIVGYFAAKIINKCQYAMSVEVLEQMQLA
                     PASEEGATKLSDKINPPGVALVTSLIVIPIAIIMAGTVSATLMPPSHPLLGTLQLIGS
                     PMVALMIALVLAFWLLALRRGWSLQHTSDIMGSALPTAAVVILVTGAGGVFGKVLVES
                     GVGKALANMLQMIDLPLLPAAFIISLALRASQGSATVAILTTGGLLSEAVMGLNPIQC
                     VLVTLAACFGGLGASHINDSGFWIVTKYLGLSVADGLKTWTVLTTILGFTGFLITWCV
                     WAVI"
     gene            complement(49441..49677)
                     /locus_tag="IT892_000796"
     CDS             complement(49441..49677)
                     /locus_tag="IT892_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134036.1"
                     /translation="MICPRCADEQIEVMAKSPVKDVWTVYQCQHCLYTWRDTEPLRRT
                     SREHYPEAFRMTQKDIDDAPMVPSIPPLLAEGKR"
     gene            complement(49688..51115)
                     /locus_tag="IT892_000797"
     CDS             complement(49688..51115)
                     /locus_tag="IT892_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAP3134037.1"
                     /translation="MAFDDLRSFLQALDDHGQLLKISEEVNAEPDLAAAANATGRIGD
                     GAPALWFDNIRGFTDARVAMNTIGSWQNHAISLGLPPNTPVKKQIDEFIRRWDNFPIA
                     PERRANPAWAQNTVDGDEINLFDILPLFRLNDGDGGFYLDKACVVSRDPLDPDNFGKQ
                     NVGIYRMEVKGKRKLGLQPVPMHDIALHLHKAEERGEDLPIAITLGNDPIITLMGATP
                     LKYDQSEYEMAGALRESPYPIATAPLTGFDVPWGSEVILEGVIESRKREIEGPFGEFT
                     GHYSGGRNMTVVRIDKVSYRTRPIFESLYLGMPWTEIDYLMGPATCVPLYQQLKAEFP
                     EVQAVNAMYTHGLLAIISTKKRYGGFARAVGLRAMTTPHGLGYVKMVIMVDEDVDPFN
                     LPQVMWALSSKVNPAGDLVQLPNMSVLELDPGSSPAGITDKLIIDATTPVAPDNRGHY
                     SQPVVDLPETKAWAEKLTAMLAARK"
     gene            complement(51115..51708)
                     /locus_tag="IT892_000798"
     CDS             complement(51115..51708)
                     /locus_tag="IT892_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAP3134038.1"
                     /translation="MRLIVGMTGATGAPLGVALLQALREMPNVETHLVMSKWAKTTIE
                     LETPYSARDVAALADFSHNPADQAATISSGSFRTDGMIVIPCSMKTLAGIRVGYADGL
                     VGRAADVVLKEGRKLVLVPREMPLSTIHLENMLALSRMGVAMVPPMPAFYNHPETVDD
                     IVHHVVARVLDQFGLEHPHARRWQGLPQVRNFSQENE"
     gene            51855..52262
                     /locus_tag="IT892_000799"
     CDS             51855..52262
                     /locus_tag="IT892_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP3134039.1"
                     /translation="MALRNKAFHQLRQLFQQHTARWQHELPDLTKPQYAVMRAIADKP
                     GIEQVALIEAAVSTKATLAEMLARMENRGLVRREHDAADKRRRFVWLTAEGEKVLAAA
                     IPIGDSVDEEFLGRLSAEEKELFMQLVRKMMSK"
     gene            complement(52383..53375)
                     /gene="rpoS"
                     /locus_tag="IT892_000800"
     CDS             complement(52383..53375)
                     /gene="rpoS"
                     /locus_tag="IT892_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HAP3134040.1"
                     /translation="MSQNTLKVHDLNEDAEFDENGVEVFDEKALVEEEPSDNDLAEEE
                     LLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV
                     VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMN
                     QTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNER
                     ITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLAR
                     RFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE"
     gene            complement(53438..54577)
                     /gene="nlpD"
                     /locus_tag="IT892_000801"
     CDS             complement(53438..54577)
                     /gene="nlpD"
                     /locus_tag="IT892_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator NlpD"
                     /protein_id="HAP3134041.1"
                     /translation="MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAP
                     ANTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVAQQPVQMENG
                     RIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVG
                     QTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSA
                     NKMLPNNKPTATTVTAPVTVPTASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASE
                     GGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLV
                     REQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR"
     gene            complement(54717..55343)
                     /gene="pcm"
                     /locus_tag="IT892_000802"
     CDS             complement(54717..55343)
                     /gene="pcm"
                     /locus_tag="IT892_000802"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HAP3134042.1"
                     /translation="MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKA
                     WDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCS
                     VERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMT
                     QLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA"
     gene            complement(55337..56098)
                     /gene="surE"
                     /locus_tag="IT892_000803"
     CDS             complement(55337..56098)
                     /gene="surE"
                     /locus_tag="IT892_000803"
                     /EC_number="3.1.3.5"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HAP3134043.1"
                     /translation="MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNS
                     LTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVI
                     YSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
                     PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVD
                     EGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW"
     gene            complement(56079..57128)
                     /gene="truD"
                     /locus_tag="IT892_000804"
     CDS             complement(56079..57128)
                     /gene="truD"
                     /locus_tag="IT892_000804"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HAP3134044.1"
                     /translation="MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHI
                     LVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLS
                     AFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYF
                     GAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQ
                     VVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQ
                     AAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVV
                     RELINTTGDYAHIAE"
     gene            complement(57125..57604)
                     /gene="ispF"
                     /locus_tag="IT892_000805"
     CDS             complement(57125..57604)
                     /gene="ispF"
                     /locus_tag="IT892_000805"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HAP3134045.1"
                     /translation="MRIGHGFDVHAFGGEGPLIIGGVRIPYEKGLLAHSDGDVALHAL
                     TDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQA
                     PKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK"
     gene            complement(57604..58314)
                     /gene="ispD"
                     /locus_tag="IT892_000806"
     CDS             complement(57604..58314)
                     /gene="ispD"
                     /locus_tag="IT892_000806"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HAP3134046.1"
                     /translation="MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHA
                     LLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWV
                     LVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGL
                     WHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPE
                     DLALAEFYLTRTIHQENT"
     gene            complement(58333..58644)
                     /gene="ftsB"
                     /locus_tag="IT892_000807"
     CDS             complement(58333..58644)
                     /gene="ftsB"
                     /locus_tag="IT892_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HAP3134047.1"
                     /translation="MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNA
                     KLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNN
                     R"
     gene            complement(58838..59161)
                     /locus_tag="IT892_000808"
     CDS             complement(58838..59161)
                     /locus_tag="IT892_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3561 family protein"
                     /protein_id="HAP3134048.1"
                     /translation="MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPML
                     IYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALF
                     MWLLG"
     gene            complement(59211..59816)
                     /gene="cysC"
                     /locus_tag="IT892_000809"
     CDS             complement(59211..59816)
                     /gene="cysC"
                     /locus_tag="IT892_000809"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HAP3134049.1"
                     /translation="MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTV
                     AGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLV
                     VLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
                     GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS"
     gene            complement(59816..61243)
                     /gene="cysN"
                     /locus_tag="IT892_000810"
     CDS             complement(59816..61243)
                     /gene="cysN"
                     /locus_tag="IT892_000810"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HAP3134050.1"
                     /translation="MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLI
                     GRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYF
                     STEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGI
                     KHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSE
                     SMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQ
                     RVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAV
                     QSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNG
                     IGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSA
                     FELELNALVRRHFPHWGARDLLGDK"
     gene            complement(61245..62153)
                     /gene="cysD"
                     /locus_tag="IT892_000811"
     CDS             complement(61245..62153)
                     /gene="cysD"
                     /locus_tag="IT892_000811"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HAP3134051.1"
                     /translation="MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVML
                     HLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINP
                     FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP
                     KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE
                     RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVST
                     TSERQGRVIDRDQAGSMELKKRQGYF"
     gene            62405..63442
                     /gene="iap"
                     /locus_tag="IT892_000812"
     CDS             62405..63442
                     /gene="iap"
                     /locus_tag="IT892_000812"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase isozyme conversion
                     aminopeptidase"
                     /protein_id="HAP3134052.1"
                     /translation="MFSALRHRTAALALGVCFILPVHASSAKPGDFANTQARHIATFF
                     PGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIA
                     AHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKN
                     TPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGV
                     KTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEVFDKAGIAVLSV
                     EATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIM
                     LPLVKELAKAS"
     repeat_region   63466..64040
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=63588..63613
                     /rpt_unit_seq="tttatccccgctggcgcggggaacac"
     gene            complement(64137..64430)
                     /gene="cas2"
                     /locus_tag="IT892_000813"
     CDS             complement(64137..64430)
                     /gene="cas2"
                     /locus_tag="IT892_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endoribonuclease
                     Cas2"
                     /protein_id="HAP3134053.1"
                     /translation="MSMVVVVTENVPPRLRGRIAIWLLEVRAGVYVGDTSKRIREMIW
                     QQISQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGVRLVSFLPVDNQ"
     gene            complement(64427..65350)
                     /gene="cas1e"
                     /locus_tag="IT892_000814"
     CDS             complement(64427..65350)
                     /gene="cas1e"
                     /locus_tag="IT892_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endonuclease Cas1"
                     /protein_id="HAP3134054.1"
                     /translation="MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHI
                     PVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQ
                     AKLALTEDLRLKVVRKMYELRFREPPPARRSVEQLRGIEGSRVRQTYALLAKQYGVKW
                     NGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYD
                     IADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSSKLTGKLIPLIEEVLAAGE
                     IEPPQPAPDMLPPAIPEPETLGDSGHRGRGG"
     gene            complement(65347..65997)
                     /gene="cas6e"
                     /locus_tag="IT892_000815"
     CDS             complement(65347..65997)
                     /gene="cas6e"
                     /locus_tag="IT892_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas6/Cse3/CasE"
                     /protein_id="HAP3134055.1"
                     /translation="MYLSRITLHTGQLLPAQLLHLVGRGEYVMHQWLWDLFPGGKERQ
                     FLYRREELQGAFRFFVLSQERPAESDIFTIECRPFAPELRTGQSLCFNLRANPTICKA
                     GKRHDLLMEAKRQVRGQVEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQ
                     LRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA"
     gene            complement(65979..66725)
                     /gene="cas5e"
                     /locus_tag="IT892_000816"
     CDS             complement(65979..66725)
                     /gene="cas5e"
                     /locus_tag="IT892_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cas5/CasD"
                     /protein_id="HAP3134056.1"
                     /translation="MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGV
                     GIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSAPD
                     LLSAIISRRDYYTDAWWMVAVATTPDASYRLEQLQDGLRHPVFPLYLGRKSHPLALPL
                     APLLLEGNASDVLRNAYQQYQDSFRELKVSLPKLQDECWWEGEHDGLVASKILRRRDV
                     PLNRQQWLFGERTINQGPWLSKEEPCTSQE"
     gene            complement(66736..67791)
                     /gene="cas7e"
                     /locus_tag="IT892_000817"
     CDS             complement(66736..67791)
                     /gene="cas7e"
                     /locus_tag="IT892_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas7/Cse4/CasC"
                     /protein_id="HAP3134057.1"
                     /translation="MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSL
                     KRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAK
                     NDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVD
                     IAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGE
                     TGFGSALFYTYICIDKDLLVENLGGDEALANQTLRAFTEAALKVSPTGKQNSFASRAY
                     ASWALAEKGTEQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECVSFD
                     VMNKQGSMKDVLDFICA"
     gene            complement(67806..68342)
                     /gene="casB"
                     /locus_tag="IT892_000818"
     CDS             complement(67806..68342)
                     /gene="casB"
                     /locus_tag="IT892_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse2/CasB"
                     /protein_id="HAP3134058.1"
                     /translation="MSIVKEEHKATLRKWHEELQEKRGNRASLRRSTTVNDVCLSEGF
                     RSLLMQTHTLWKIEAQEWRFTALALVAAVSANVKAIDERQPFAAQLAAVMSEGRFTRL
                     SAVKTPDDLLRQLRRAVKLLNGSVNLISLAEDIFRWCQESDDLLNHHRRQQRPTEFIR
                     IRWALEYYQAGDADNEQN"
     gene            complement(68339..69901)
                     /gene="casA"
                     /locus_tag="IT892_000819"
     CDS             complement(68339..69901)
                     /gene="casA"
                     /locus_tag="IT892_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse1/CasA"
                     /protein_id="HAP3134059.1"
                     /translation="MNSFSLLTTPWLPVRYKDGTTGKLAPVDLADENVVDIAAPRADL
                     QGAAWQFLLGLLQTSFAPKDHRRWDDIWEDGLESEKLREALLSLEHAFQFGPDSPSFM
                     QDFEALTGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEYLCPHCSALALFSLQLNA
                     PSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWLNVMPQDEADLPLPKKFDD
                     LVFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQNDA
                     LLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKS
                     ENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLDKKEGQIP
                     KLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRHIE
                     EGQDADELLSKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQNA
                     KAAREKKQEAAE"
     gene            complement(69999..72656)
                     /locus_tag="IT892_000820"
     CDS             complement(69999..72656)
                     /locus_tag="IT892_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HAP3134060.1"
                     /translation="MTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKSNCF
                     GLTDYFRQLGFADTEQAAQFFAWLLCWHDTGKFARSFQQLYLHPQLKVPEGARKNYEK
                     ISHSTLGYWLWHHYLSEYEELLPSSSLSPRKLKRVMEMWMPITTGHHGRPPDRIDELD
                     NFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGS
                     STRFFPRVAHPMDIKGYWQKTLVQAQNALTVFPLKAKVAPFTGINTLFPFIENPTPLQ
                     QKVLDLDISQPGPQLFILEDVTGAGKTEAALILAHRLMAAGKAQGLFFGLPTMATANA
                     MYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGC
                     AAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYM
                     SCILEGLIERQARGGNSVILLSATLSQQQCDKLVAAFARGTEGQQEAPFLEKDDYPWL
                     THVTKSDVHSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQGKCIAWIRNSVDDA
                     IKVYRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKEDSSQRAGKVLICTQ
                     VLESSVDCDMDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILA
                     PVWDDAPGDEWFGSAMRNSAYVYPDHGRIWLTQRVLREQGAIQMPHAARLLIESVYGE
                     DVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESV
                     SLWLATCIASVVKPYANGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRQWCIEQRK
                     DPEMANVILVTDDESCGYSAMEGLTGKVG"
BASE COUNT        17109 a        19817 c        18717 g        17022 t
ORIGIN      
        1 ttactttact gcagattttt tgataccgct actaaagccg tatcaagtaa gagatggtgc
       61 atccgggagg attactcgcc ttgcggctcg cccttcgggc cgttgctaaa gcaacgttat
      121 cctccctggt gcctgcggtt attaccgcca cctcttccat accttcatcg ctgaaagtac
      181 gtagaatatg gtgcatccgg gaggattcga acctccgacc gctcggttcg tagccgagta
      241 ctctatccag ctgagctacg gatgcaaatg gcggtgaggc ggggattcga accccggatg
      301 cagcttttga ccgcatactc ccttagcagg ggagcgcctt cagcctctcg gccacctcac
      361 cacacgcctc ttacgagtgc ttcgaagaac ttgtttatcg ctcatcgtcg ctgcgtggcg
      421 cacatattac tttctgagac ttataagtca aacaattttt cccacacttt tatcgtttgc
      481 acacttcacg ctcaattagt ctgtaaaaac gtcaaaaaga gtgttttatc aacagaaaaa
      541 cggaggtctg acagatagca gtaatgcaaa aaaatggaga cttaagttga atgaacggga
      601 gtaaagcgaa aagactatag agtgaaggag agattttgag ggtgcgtctc accgataaag
      661 atgagacgcg gaaagattag taactggact gctgggattt ttcagcctgg atacgctggt
      721 agatctcttc acggtgaaca gaaacttcct tcggggcatt tacgccaata cgtacctggt
      781 tgccctttac ccctaaaact gtcacggtga cctcatcccc aatcatgagg gtctcaccaa
      841 ctcgacgagt cagaatcagc attctttgct ccttgaaaga ttaaaagagt cgggtctctc
      901 tgtatcccgg cattatccat catataacgc caaaaagtaa gcaatgacaa acacattaca
      961 tgtaagcagt catggcatta cattctgtta aacctaagtt tagccgatat acacaacttc
     1021 aacctgactt tatcgttgtc gatagcgtta atgcgaatgc cgtgaagcga gtccacggca
     1081 ttgcctgacg cttatattat tgcaatttcg cgctgaccca gcctttcaca ctggctaacg
     1141 ctgcaggtaa ggccgcagca tccgtaccac cggcttgcgc catgtcagga cgtccaccac
     1201 ccttgccgcc cacctgctga gcgaccatac caatcagttc ccctgctttc acacgatctg
     1261 tgacgtcctt agatacgcct gcaatcagag aaaccttacc ttcggctacc gttgccagca
     1321 cgataattgt cgaccccagc tgatttttta aatcgtcaac catggtacgc aacattttcg
     1381 gctcaacacc gctaagctcg ctaaccaaca gcttaacacc attaacatca attgccttac
     1441 tggaaagatt tgcgctctcc tgtgcggcag cttgttcttt aagctgttgt agttcttttt
     1501 ctaactgacg cgtacgttcc agtactgagc gcactttatc agccagatta ttgctatcgc
     1561 ctttcagcag atgcgcgact tcgcttaagc gatcgctgtc tgcatgaacg gtggcgatag
     1621 cgccttctcc ggttaccgct tcgatacgac gaacgcctgc agcagtaccc gattcagaga
     1681 tgatgcggaa cagaccaata tcaccggtgc ggctggcgtg agtaccgcca cacagctcgg
     1741 tggagaaatc gcccatgctc agcacgcgta cgcgctcatc atacttctcg ccgaacagcg
     1801 ccatcgcacc tttcgctttc gccgcttcga gatccatgat gttggtttcg atcggcaagt
     1861 tacggcgaat ctgtgcgttc accaggtctt cgaccgcacg aatctcttct ggtttcatcg
     1921 cttcgttgtg tgagaagtcg aagcgcagca ctttgtcgtt aaccagtgaa cctttctgcg
     1981 atacatgagt acccagaacc tggcgcagcg cagcgtgcat caggtgcgtt gcggagtgat
     2041 tcagacgaat acgggcgcga cgagcttcat caacatcagc ctgcaccgcg tcgcccactt
     2101 tcagagaacc cgcagcaagt ttaccgatgt gaccaatcgc ctggccgtat ttctgcgtat
     2161 cttccaccgc aaaggagaag ttagcgcctt tcagttcgcc tttatcacca acctgaccgc
     2221 cggattccgc atagaatggc gtttgatcca gcacgaccac agcttcctgg cctgcattga
     2281 tggcatcaac cgctttacca tcaacaaaca gcgcggtcac tttgccgttc agttccagat
     2341 ggtcatagcc tttaaattca gatgcgctgt caacacggat cattgcgttg taatcggcac
     2401 caaagccgct ggcttcgcgc gcgcgacgac gctgctcttc cattgctgct tcgaaaccag
     2461 cttcgtcaac tttgatgttg cgctcacgac aaacatcagc cgtcaggtca accgggaagc
     2521 cataggtgtc gtacagacgg aaagccgttt cgccatccag cgtatcacca gaaagttttg
     2581 ccagctcttc atccagcagc gccagaccgc gctccagagt acgggcaaac tgctcttctt
     2641 cagtcttcag cacctgctca acctgcgcct gctggcgttt caggtcttca cccgcagagc
     2701 ccataacgtc gatcagcgga ccaaccagtt tgtagaagaa ggtttctttc gcgccgagca
     2761 tattaccgtg acgcactgcg cgacgaatga tacgacgcag tacataacca cggttttcat
     2821 tggacggcat tacgccatcc gcgatcagga acgcacaaga acgaatgtgg tcagcgatta
     2881 cacgcagcga tttgttgctc aaatcggtcg cgccagtgac tttcgctacc gcctggatca
     2941 gcgtacggaa caggtcgatg tcatagttag agttaacgtg ttgcagcacc gcagcaatac
     3001 gctccagacc cataccggta tctacagacg gcttcggcag cggttccatc gtgccatctg
     3061 cctggcggtt gaactgcatg aagacgatgt tccagatctc aatgtagcgg tcgccatctt
     3121 cttccggact tcccggaggg ccaccccaaa tgtggtcgcc gtgatcgtag aagatttcgg
     3181 tgcacgggcc gcacggacca gtgtcaccca tctgccagaa gttgtcagat gcgtatggcg
     3241 cacctttgtt atcgccgatg cgaataatac gttcgcgcgg gatccctact tctttttccc
     3301 agatttcgta ggcttcgtcg tcgctttcat agacggtaac ccacagacgc tctttcggca
     3361 gggcaaacca tttttcactg gtcagcagtt cccatgcaaa ctgaatggca tcgtgtttga
     3421 aatagtcgcc gaagctgaag ttgcccagca tttcgaagaa ggtatggtga cgcgcggtgt
     3481 aaccgacgtt ttccaggtcg ttgtgtttac cacccgcacg cacgcagcgt tgggaagtgg
     3541 tagcgcggga ataattacgc ttgtcgagcc caaggaacac atccttgaac tggttcatcc
     3601 cggcgttggt aaacaacaaa gttgggtcgt tatggggtac cagggagctg ctggcaacta
     3661 cctgatgtcc cttactatgg aaaaagtcga gaaacgcctg acggatctca gcggtgctct
     3721 tgctcataat tatcctgaaa tcaagctaac gaaatatcgc taccagccgt tgcgtgtcgt
     3781 taaccgccgg gctggtaact gaaaagtggg aataagataa gttttcttga ctgggaagta
     3841 aaatcccgta tgcgttcagt cggcaaaatt tcgccaaata tcctggatat cttccatcag
     3901 atagccacga tagagcagaa aacgctggat cttaactttt tctgaaaaga cagttggcaa
     3961 aggttcgcca tattttcgcg tcgcctgatc gcgcgccagt gcgcaccagt cgatgtcaca
     4021 ttcacgcatc gctttttctg tcgcttcgcg ggaaatacct ttctgattca gttcctgacg
     4081 aatacgcgca ggtccataac ctttgcggct acggctggcg ataaagcgcg caacaaatcg
     4141 actgtcatcg agatagccat gttcatggca ccaggcgata acgcgctcgt aatcttctgc
     4201 cgtggcatca atctcttccg ggccattttt gcccatgatc ggtgccgcga gtttacgtcg
     4261 caattcttgc tcactgtgat cgcgcaccgc cagaatgcgt accgcacgat ccaacaggcg
     4321 agcatatgcc gggcgacggg acgttgattc tgtcatggca tatccttaca acttaaaaaa
     4381 gcaaaagggc cgcagatgcg acccttgtgt atcaaacaag acgattaaaa atcttcgtta
     4441 gtttctgcta cgccttcgct gtcatctaca gagaaatccg gcgttgagtt cgggttgctc
     4501 agcagcaact cacgtacttt cttctcgatc tctttcgcgg tttccgggtt atctttcagc
     4561 caggcagtcg cattcgcttt accctgaccg atcttctcac ctttgtagct gtaccacgca
     4621 cctgctttct cgatcagctt ctctttcacg cccagatcaa ccagttcgcc atagaagttg
     4681 ataccttcgc cgtagaggat ctggaattca gcctgtttaa acggagcagc gattttgttc
     4741 ttcaccactt tcacacgggt ttcgctaccc accacgtttt cgccctcttt caccgcgccg
     4801 atacgacgga tgtcgagacg aacagaggcg tagaatttca gcgcgttacc accggtagtg
     4861 gtttccgggt taccgaacat cacaccaatt ttcatacgga tctggttgat gaagatcagc
     4921 agcgtgttgg actgcttcag gttacccgcc agcttacgca tcgcctggct catcatacgt
     4981 gccgcaaggc ccatgtgaga gtcgccgatt tcgccttcga tttccgcttt cggcgtcagt
     5041 gccgccacgg agtcaacgac gataacgtct actgcaccag aacgcgccag ggcgtcacag
     5101 atttccagtg cctgctcgcc agtgtccggc tgggagcaca gcaggttgtc gatatcgacg
     5161 cccagtttac gtgcatagat tgggtccagc gcgtgttcag catcgataaa cgcacaggtt
     5221 ttaccttcac gctgcgctgc ggcgatcacc tgcaacgtca gcgtggtttt accggaagat
     5281 tccggtccgt agatttcgac gatacggccc atcggcagac cacctgcccc aagcgcgata
     5341 tccagtgaaa gcgaaccggt agagatggtt tccacatcca tggaacggtc ttcacccagg
     5401 cgcatgatgg agcctttacc aaattgtttc tcaatctggc ccagtgctgc cgccaacgct
     5461 ttctgtttgt tttcgtcgat agccattttt actcctgtca tgccgggtaa taccggatag
     5521 tcaatatgtt ctgttgaagc aattatactg tatgctcata cagtatcaag tgttttgtag
     5581 aaattgttgc cacaaggtct gcaatgcata cgcagtagcc tgacgacgca ccgcatcacg
     5641 gtcaccgctg aagcattccc gccgggtaat accttcgccg cgggcggtgg caaaagcaaa
     5701 ccagacggtg ccgacaggct tctcttcact gccgccatcc ggcccggcga taccactaat
     5761 agacacagca taatcagcac gagccgcttt cagtgcgcct atcgccattt ccaccacgac
     5821 aggttcgctc accgcgccat gctgcgccag cgtctcttcg cgtacaccga tcatttgcgc
     5881 tttcgcttcg ttactgtagg tgacaaatcc gcgttcaaac caggcggaac tgccggcaat
     5941 atcggtaatc actttcgcta cccaaccacc ggtacaagac tcagcagttg ttacggttgc
     6001 gccacgggct ttcagcgcct gcccaacctg ttcgcttaac tgcatcagtt cactgtcagt
     6061 catcacaacc tctgtcagtc aaaaatttat gccggacaag atagcacttt cgtcaggaag
     6121 atggtgttgg cgttgcaatt ttacgaggag gattcagaaa aaagctgatt agccagaggg
     6181 aagctcacgc tcccctcttg caaatagtta ctgcacgcgc gccagcgcca cggcttgtcc
     6241 taactgccag accgccattg cgtaatgggt gctgtggtta taacgggtaa tggtgtagaa
     6301 gttcggcaga ccgtaccagt actggtaacc tgttccaaca tccagacgca gcaggctggc
     6361 ttgttgatgg ttgcccagcg gctgctgtgg cgttaaacct gccgcggtaa gctgcgaaat
     6421 gctgtacttg gttttgaagc catttggcaa gcctggagcc tgaccgtttg ccattaccgc
     6481 gacctgatcg cctttcaccc agccgtgcgc tttgaaatag ttcgccacgc taccgatcgc
     6541 atcaaccgga tcccacaggt tgatatgccc gtcgccgctg aaatctaccg catattgttt
     6601 gtaagacgac ggcataaact gtccgtagcc catcgccccg gcaaaggaac ctttcagatt
     6661 gagcggatcg tcctgctcat cgcgcgccat cagcaggaaa gtttccagct cgccagagaa
     6721 atactccgcg cggcgtgggt agttaaatga cagcgttgcc agcgcatcga ggatacgggt
     6781 tttccccatc acgcgccccc agcgggtttc aacgccgata atcccgacga taatttccgg
     6841 cggtacgcca tacacctgcc acgcgcgatt caacgcatct tcatactgat tccagaaaac
     6901 cacaccattc tgcacgttgt ccggcgtaat aaattttttg cgataacgca gccatgcgcc
     6961 gttcggacct gatggcggtt tcaccgatgt ggttggtgcc tggttatcca tcagccgcag
     7021 taccgaatcc agacgtttcg cctgagagag aatttcctgc aactgctgac gatcgaaacc
     7081 gtgtttgttc accattttgt cgatgaactg ctgggcattc gggttattgg cgaagtcacc
     7141 gcccatctgc atcacattgt gctgcggctc aagcaggaag ccgccagacg gcgttccggt
     7201 ggtcgtttca gtctcagtag gttttggctt gctgctacag gcggcaagca acacaaaaag
     7261 gggaagcaat gttacataac gacgcttgaa catgaggggt ccatttaaca gattcaacca
     7321 agggcaagta tggtaaagca tcacgccccg cacaaggaag cggtagtcac tgcccgatac
     7381 ggactttaca taactcaact cattctcctc gctatccttt tattcaaact ttcaaattaa
     7441 aatatttatc tttcattttg cgatcaaaat aacactttta aatctttcaa tctgattaga
     7501 ttaggttgcc gtttggtaat aaaacaataa atcctgaagg agagaacaat gatagaaacc
     7561 attactcatg gtgcagagtg gtttatcggg ctgttccaaa agggcggaga ggtgtttacc
     7621 gggatggtga ccggcattct tccgctgttg attagtctgc tggttatcat gaacgcactg
     7681 attaatttta tcggtcagca tcgtattgaa cgttttgctc aacgttgcgc cggtaaccct
     7741 gtttcccgtt acctgctgct accgtgcatt ggtacgtttg tcttttgtaa tccaatgacc
     7801 ctaagcctgg gtcgctttat gccggaaaaa tacaaaccca gctactacgc agcggcctct
     7861 tatagctgcc actccatgaa tggcctcttc cctcatatca accctggcga actgtttgtt
     7921 tatcttggca ttgccagcgg tctgacgacg ctgaatctgc cacttggccc actggcagtg
     7981 agttatctgc tggttggttt ggtcaccaac ttcttccgcg gctgggtgac cgatctgacc
     8041 accgccattt ttgagaaaaa gatgggtatt caacttgaac aaaaagttca cctggcagga
     8101 gcaacatcat gacgcgtatt cggatcgaaa aaggaacggg tggctggggc ggcccgcttg
     8161 agctggaagc cacgccgggc aaaaaaatcg tctatatcac cgccggtacc cggcctgcga
     8221 ttgttgacaa actggcacag cttactggct ggcaggctat tgacggattt aaagaaggtg
     8281 aacccgcgga ggcggaaatt ggtgtcgcgg taatcgactg tggcggcaca ttacgctgcg
     8341 gcatctatcc gaaacgacgt attcccacca ttaatatcca ctcgacgggc aagtccggtc
     8401 cactggagca gtacattgta gaagatattt atgtctctgg cgtaaaagaa gaaaacatca
     8461 ctgtagtggg tgatgcgaca ccacaaccct cttccgtggg ccgtgactat gacaccagca
     8521 agaaaatcac cgaacaaagc gatggtttac tggcgaaggt gggaatgggt atgggttctg
     8581 ccgttgccgt gttgtttcaa tctggtcgtg acaccatcga cactgtatta aaaaccattc
     8641 tgccgtttat ggcgttcgtc tcggcgctta tcggcatcat tatggcttcc ggtcttggcg
     8701 actggattgc ccacggtctt gctccgctgg ctagccatcc tctggggctg gtcatgctgg
     8761 cgctcatctg ctccttcccg ctgctttcac ctttcctcgg cccaggcgca gttatcgcac
     8821 aggttatcgg cgtattgatt ggcgtgcaga ttggtctcgg caatattccg ccgcatctgg
     8881 ctttacctgc actgtttgcc atcaacgcgc aggcggcctg cgacttcatc ccggtcggtt
     8941 tgtcgctggc ggaagcccgt caggacacgg ttcgcgtcgg tgtcccttct gttctggtga
     9001 gccgcttttt aaccggcgcg ccaactgtac tgatcgcctg gtttgtctcc ggttttatct
     9061 atcaatagag gctgaaacat gaccgttatt tatcagacca ccatcacccg tatcggcgcg
     9121 agtgccactg acgccctcag cgaccagatg ctcatcacct ttcgtgaagg cgcgcctgcg
     9181 gatctcgaag agtattgctt cattcattgc cacggcgagt tgaaaggtgc actccatccc
     9241 ggtttgcaat tttcgctcgg gcagcatcgc tatccggtga ccgccgttgg cagcgtggcg
     9301 gaagacaacc ttcgcgaact gggtcatgtc accctgcgct tcgatggttt aaacgaagcg
     9361 gaattcccgg gcactgtcca tgtggcaggc cctgtacccg acgatatcgc gccgggatcg
     9421 gttttgaagt ttgaatctgt taaggagtaa aaaatgaatc aggttgccgt tgttatcggt
     9481 ggtgggcaaa ccttaggcgc gttcctgtgc cacggtctgg ctgccgaggg gtatcgcgtc
     9541 gcggttgtcg atattcagag cgacaaagcc gcaaatgtgg cacaagaaat taacgccgaa
     9601 tatggtgaag gtatggcgta cggttttggt gctgacgcca ccagtgagca aagcgttctg
     9661 gcgctctctc gtggggtaga tgaaatcttt ggtcgcgtgg atttgctggt ctacagcgcc
     9721 ggaattgcaa aagcagcctt tatcagcgac ttccagctcg gcgattttga ccgttcgcta
     9781 caagtgaatc tggtgggtta tttcctgtgt gcccgtgaat tttcgcgttt gatgatccgc
     9841 gacgggattc aggggcgcat tattcagatc aactcgaaat ccggcaaagt gggcagcaaa
     9901 cacaactctg gttatagcgc cgcgaaattt ggtggcgtcg ggctgactca atcactggcg
     9961 ctggatctgg cggagtacgg cattacggtg cattcactga tgctcggtaa tctgctgaaa
    10021 tcgccgatgt tccagtcgct gttgccacaa tacgcgacca agctgggtat caaaccggat
    10081 caagtcgagc agtattacat cgataaagta ccgctcaaac gcggctgcga ttatcaggat
    10141 gtactgaata tgctgctgtt ctacgccagt cctaaggcgt cgtactgcac tggtcagtcg
    10201 atcaatgtca ccggcggtca ggtgatgttc tgatcaacag cggagatccg ttaaggatct
    10261 ccgcgagact aataaaatgc ctgatgcgct acgctcatca ggcatacagg acttccgcca
    10321 ctacattacg gagaagttat ggtatccgca ctcatcaccg tcgccgttat cgcctggtgt
    10381 gcgcaactgg ccttaggcgg ttggcaaatt tctcgtttta accgtgcctt cgacacacta
    10441 tgccagcaag ggcgggttgg cgtgggccgt tccagcgggc gctttaaacc gcgggtcgtg
    10501 gtcgtcatcg ccctggacga tcagcaacgc atcgtcgaca ccttgtttat gaaaggactg
    10561 accgtcttcg cccgaccaca aaaaattccc gcaattaccg gtatgtatgc gggtgattta
    10621 cagcccgatg tgatctttcc caatgatcca ctatcacaga atgctctatc attggcgctt
    10681 aaactgaaac gtggataatt tcgttgtgaa tgttacttgc ttgcgaagtt atcattttga
    10741 aacctaaatc aggtaatcac gcccatgaaa cctcgtcagc gtcaggccgc cattctggag
    10801 tatctgcaaa agcagggtaa atgctcggtt gaagaattgg cgcaatactt tgacaccaca
    10861 ggcacaacca ttcgcaaaga tctggtcatt ctggaacatg ccggaaccgt cattcgtact
    10921 tatggcggag tggtgttgaa taaagaggaa tccgatccgc ctatcgatca taaaacactc
    10981 atcaacaccc acaagaaaga gctgattgca gaagctgccg ttagttttat ccatgatggc
    11041 gattcgatca ttcttgatgc tggcagtacc gttttgcaga tggttcccct gctctcgcgc
    11101 tttaataaca tcacagtgat gaccaacagc ctgcatatcg tcaatgcgct atccgaactg
    11161 gataacgaac aaactatcct gatgccaggc ggaacatttc gtaaaaaatc ggcctcattt
    11221 cacgggcaac tggcagagaa tgccttcgag catttcacct tcgataaatt gtttatgggc
    11281 accgacggca tcgatctcaa tgcgggcgta accacgttca acgaggttta taccgtcagt
    11341 aaggcaatgt gcaatgccgc gcgcgaagtg attttgatgg cagactcatc aaagtttggc
    11401 cgtaaaagcc ccaacgtagt ttgcagtctt gaaagcgtcg ataagctaat taccgacgca
    11461 ggtatcgatc cggcgtttcg tcaggcgctg gaaaagaaag ggatcgatgt gatcataacc
    11521 ggagagagca atgagtgaag cactactgaa cgcgggacgt cagactttaa tgctggagtt
    11581 gcaggaagca agccgtttac cggaacgtct gggcgatgat tttgttcgcg ccgccaatat
    11641 catcctgcac tgcgaaggca aagtggtggt ttcgggaatt ggcaaatcgg gccacattgg
    11701 taagaaaatc gccgcaacgc ttgccagtac cggcacaccg gctttttttg tccatccggc
    11761 agaggcactg cacggcgatc tggggatgat cgaaagccgc gatgtgatgc tgtttatctc
    11821 ttactccggt ggcgcgaagg aactggatct gattattccg cgtctggaag ataaatctat
    11881 cgcactgctg gcgatgaccg gcaaaccgac gtcaccgctg ggcctggcgg cgaaagcggt
    11941 gctggatatc tccgtagaac gcgaagcctg tccgatgcac cttgcgccga cctccagcac
    12001 cgtgaatacc ctgatgatgg gtgacgcgct ggcgatggcg gtcatgcagg cgcgcggatt
    12061 taatgaagaa gattttgccc gctcccaccc tgctggagca ttgggtgctc gcttgctgaa
    12121 taaagtgcat catctgatgc gccgtgatga cgctatcccg caggtagcgt taaccgccag
    12181 cgtgatggat gcgatgctgg aactcagccg cactggtctg gggctggtgg cggtatgtga
    12241 cgctcaacaa caggtacaag gcgtctttac cgacggcgat ttacgtcgct ggctggttgg
    12301 cggcggcgca ctcaccacgc cagttaatga agcgatgacg acaggcggca ccacattaca
    12361 ggcgcaaagc cgtgccatcg acgccaaaga gatcctgatg aagcgcaaaa tcactgccgc
    12421 accggtggtg gatgaaaacg gcaaactcac cggcgcaatt aacttgcagg atttctatca
    12481 ggccgggatt atttaatcct tcaatcccag acgtttcgcc agccgatgca ggttggcgac
    12541 gtcggtttcc agcatccgcg cacaggcagc ccagttgtga tgattttgtg ccagtgcctg
    12601 acgaatagtt tcacgctgga acgcttctgt cgcttcacgc aggttttgct taacaacggg
    12661 caccgccgcc gcttctggcg gcggcaacgt cacctcagga aaagcaaaat gttgcgcctc
    12721 aagaatcact tcatcgccgc tgcgagtggc tctcgacagt actaccgccc gatgaatagc
    12781 atgttccagt tcgcgcacgt ttcccggaaa actgtagtgt tgcagtaaat ttcgcgcccc
    12841 ggcacttaat accacgcggg agagccccag ccgcaaacga cactgctcgc agaaataccc
    12901 cgccagcaga atgacatcat cgccccgctc acgcagcggc ggcaccgaaa gtggaaacac
    12961 gctcaggcga tgaaacaaat cggcgcggaa tcgccctgcc agcacctctt cgcgtaaatc
    13021 gcggttagtc gccgccagca cgcgcacatc gacccgcaaa ctgcggtcat cgccaacgcg
    13081 ctgaatatcg ccatactgca acaccctcag cagcttggcc tgcaatgcca acgacaactc
    13141 gccgatctca tcgagaaaca gtgtgccgtt atccgccatt tcaaacttcc cgctgcggtt
    13201 actgatagca ccagtaaacg cccctttcac atgcccgaac agttcacttt ccgccacact
    13261 ttccggcagt gcggcacagt tgagatagac cagcggattc accgcccttg gcgaggcttc
    13321 atgaatcgct ttcgccacca gctccttacc ggttcccgtc tcaccgctga ttaagacgtt
    13381 gagatcggac gccgccacaa tctcaatctc tttttttaat tgcgtcatac ctggcgacag
    13441 accgatcatc tgcgtctgtt tcaccgcttc aaacggcgtg gcatcgcctg gcagcatatt
    13501 ctggctttcc agttgttcaa tcagcaacgc attgcttaac gctcccgccg ccagcgcggc
    13561 aatcaggcgt aactcttcgt cgctgaaaac atcgaactga tcgggctgca tcccgtcgag
    13621 cgtcaatgcg ccgatcaggt tttgcccggc aaacaatggc agaccaacgc aggcgtgaac
    13681 cttcagactc tcctgcccgg gaatcaaacc gtcataggga tcgggcaatt cgctgtctgc
    13741 gggaaagcgc accacgtccc cggcgcgggc aatcgcttcc agccgtggat gcccttccag
    13801 cgcaaagcgt ctaccgagta catcctttgc cagcccgtcg atggcaagcg gaataaactg
    13861 ccgcgagtcg taacgtagca atgcagacgc atcgcactcc agcacctgac gcagcgtggt
    13921 gatcaggcgc tgaaaacgat cctgatgacc aatcccacgc tgcaattcga tggcgatatt
    13981 cgccagcaca tcaacggaaa aactcatctt tgcctcactg tcaatttgac tatagatatt
    14041 gtcatatcga ccatttgatt aatagtcatt ttgactactc attaatgagc ataattttat
    14101 ttatagagta aaaacaatca gataaaaaac tggcacgcaa tctgcaatta gcaagacatc
    14161 tttttagaac acgctgaata aattgaggtt gctatgtcta ttgtggtgaa aaataacatt
    14221 cattgggttg gtcaacgtga ctgggaagtg cgtgattttc acggcacgga atataaaacg
    14281 ctgcgcggca gcagctacaa cagctacctc atccgcgaag aaaaaaacgt gctgatcgac
    14341 accgtcgacc ataaattcag ccgcgaattt gtgcagaacc tgcgtaatga aatcgatctg
    14401 gcggatatcg attacatcgt gattaaccat gctgaagagg accacgccgg ggcgctgacc
    14461 gaactgatgg cgcaaattcc cgatacgccg atctactgta ctgctaacgc tatcgactcg
    14521 ataaatggtc atcaccatca tccggagtgg aattttaatg tggtgaaaac tggcgacacg
    14581 ctggatatcg gcaacggcaa acagctcatt tttgtcgaaa cgccaatgct gcactggccg
    14641 gacagcatga tgacttacct gacaggcgac gcggtgctat tcagtaacga tgctttcggt
    14701 cagcactact gcgacgagca tctgttcaac gatgaagtgg atcagacgga gcttttcgag
    14761 cagtgccagc gttactacgc caatatcctg acgccgttca gccgcctggt aacgccgaaa
    14821 attaccgaga tcctgggctt taacttacca gtcgatatga tagcgacctc tcacggcgtg
    14881 gtatggcgcg ataacccgac gcaaattgtc gagctgtacc tgaaatgggc ggcggattat
    14941 caggaagaca gaatcaccat tttctacgac accatgtcga ataatacccg catgatggct
    15001 gacgctatcg cccagggtat tgcggaaacc gacccacgcg tggcggtgaa aattttcaac
    15061 gtcgcccgaa gcgataaaaa cgaaatcctg accaatgtct tccgctcaaa aggcgtgctg
    15121 gttggcactt cgacgatgaa taatgtgatg atgccgaaaa tcgccgggct ggtggaagag
    15181 atgaccggat tacgcttccg taacaaacgc gccagtgctt tcggctctca cggctggagc
    15241 ggcggtgcgg tggatcgtct ttccacacgc ctgcaggatg caggtttcga aatgtcgctt
    15301 agcctgaaag ccaaatggcg accggaccag gacgctctgg agttatgccg tgaacacggt
    15361 cgcgaaatcg cccgtcagtg ggcgctcgcg ccgctgccgc agagcacggt gaatacggtg
    15421 gttaaagaag aaacctctgc caccacgacg gctgacctcg gcccacggat gcagtgcagc
    15481 gtctgccagt ggatttacga tccggcaaaa ggcgagccaa tgcaggacgt tgcgccagga
    15541 acgccgtgga gtgaagtccc ggataacttc ctgtgcccgg aatgctccct tggcaaagac
    15601 gtctttgacg aactggcatc ggaggaaaaa tgagcaacgg cattgtgatc attggttcgg
    15661 gctttgccgc ccgccaactg gtgaaaaata ttcgcaaaca ggacgccagt attccattaa
    15721 ccctgattgc cgccgacagc atggatgagt acaacaaacc ggacctcagc catgttatca
    15781 gtcaggggca acgtgccgac gaccttaccc gccagacggc gggtgaattt gccgagcagt
    15841 ttaatctgcg cctgtttccg cacacctggg taacggatat cgatgccgaa gcccatgtgg
    15901 tgaaaagtca gaataatcag tggcaatacg acaagttagt gctggcaact ggtgccagtg
    15961 cctttgtccc gccagtgcct gggcgtgagt taatgctgac gttaaatagt cagcaagagt
    16021 atcgcgcctg tgaaacgcaa ctgcgggatg cccgacgcgt gttgattgtc ggcggtggtt
    16081 tgattggtag cgaactggcg atggattttt gtcgtgcagg caaagcggtc acgctaatcg
    16141 acaacgctgc cagtattctg gcgtcgttaa tgccaccaga agtaagcagc cgcttgcagc
    16201 atcggttgac ggagatgggc gttcatctgc tgttgaaatc tcagttgcag gggctggaaa
    16261 aaacggattc tggcattctg gcaacgctgg accgccagcg tagcatcgaa gtggatacgg
    16321 taattgccgc caccggactg cgcccggaaa ccgccctggc acgacgcgcc gggctgacga
    16381 ttaatcgcgg cgtttgcgtc gatagttatc tgcaaaccag taatgccgat atttatgcgc
    16441 tgggcgattg cgcggaaatt aacggtcagg tattgccgtt cctccagccg attcaactta
    16501 gcgcgatggt gctggcaaaa aatcttctcg gcaataacac gccgctgaaa ctcccggcga
    16561 tgctggtgaa aatcaaaacg ccggaattac ctctgcatct ggcaggcgaa acccagcgtc
    16621 aggatttacg ctggcaaatt aataccgaac gccagggaat ggtggcgcgc ggtgttgatg
    16681 atgccgacca gcttcgcgcc tttgtggtca gtgaggatcg gatgaaagag gcgtttggat
    16741 tgttgaaaac gttgccggta taggcatgtt tttctccctc gcccaaaggg cgaggggact
    16801 gtccgcgctc tatttacgct tagttacgcc acatccgcca ctatgcagta tgcaggatgc
    16861 gcgccgcagc aataaccccc tgccccagag acaaaccgcc atcacctgcc ggtaaactct
    16921 gcggaaagag taatgtgaaa tcagcgagat aatgcgacag acgtgtacgc agcaatcggt
    16981 tatgaataac cccaccgcta aataccagcg tagtgatacc gcgcatcgtg gcctgctcac
    17041 gcatcaacgc ggcaaaaccc tgcgccagcg catcatgaaa cgcccacgcg cgttgattaa
    17101 ccggtgcctg ccagttcagc cactgctgcc agaaagtggc gagatccagt tgattgtcca
    17161 ccagcggcat cgtcaccgga tgcgtcactc cgtcgcacga agctgcgagc gcctccagag
    17221 cacaagccgc ttcaccttca taacttaacg tggctggcgc gcagcccagc gccgccgcca
    17281 cagcatcgaa caaacgccca cacgatgacg ccagcggcgc gttaattcca cgctcaatgg
    17341 cccgcgccag cacgctccag ttttgctgtt gcacacttgc cgtttcaggg taattctgcc
    17401 actccggcac aaagcgcagg cactgcgcca gcaggttacg ccacggctgc tttgcagcca
    17461 aatcgccccc cggaagcgcc accgcaggca agccgcccag gtgctcacat tcgcgatagt
    17521 tcacccgcag gcattcaccg ccccacaaag cgccgttctc ccccataccg ataccgtcga
    17581 gcgtcaacgc aatgacatca ccgccatcca gcggccactg atgctctgcc agacacgccg
    17641 ccgcatgagc atgatgatga agcatcgttt gcgtcggcag attcatttcg cgcgcccact
    17701 ggctggagac atagcccgga tgcacgtcat gcacaacgta ttgcggggta aaatcgtaga
    17761 tgttttgcat caggcgtaac gcttcgcgcc actgcatctg gatgccatcg tcacttaaat
    17821 cgcccagatg ctgactcaac accgcttgtt cgccgcgcac caggcagaag gtgtttttca
    17881 gatccgcgcc gagacacagc acaggcggaa catttttaaa gcccggaggc aaagccagcg
    17941 catccggcac atacccccgc gaacggcgca gcatttcgcc gctttcgcgc actaccgaat
    18001 catccatccg ctgcacgatg tcgcggttat gtagcaagaa tccgtcggca atgccctgca
    18061 aatccgccag cgcctgttcg ttgctgatag ccggtggttt accgctcagg ttgccggagg
    18121 tcatcaccag cggacattgc agttcctgta acagcaaatg ctgaagcgga ttcgcaggca
    18181 acatcacccc aacttcgtta aggccagggg cgatatcatc acaaagctca ggaacgtatt
    18241 ttttatccac cagcacaatc ggcgcggcgg gtgtggtaag caactgacgg gcagcgtctg
    18301 gtaaaccttc tgccactggc aacataaccg ccagcggttt cgccgggcga tgtttgcgcg
    18361 cccgcagtgt cgccaccgcg ttactgttac gcgcatcgca ggcgagatga aatccgccaa
    18421 tccctttgat ggcgacaatg ttgcccattt ttaactgtgc gatagctgcc tgtaatgccg
    18481 cctcttgttc tgcatgttca ccatgactta tccattcaag atgtgggcca cactccgggc
    18541 aggccaccgg ctgggcgtgg aagcgacgat cgagcgggtc gcgatattct ttgtcacagg
    18601 ccggacacag cggaaacgcc gccatcacgg taaacgggcg atcgtaaggc atcgcgcgaa
    18661 taatggtgaa acgcgggcca cagtgggtac agttgataaa cggataacgc cagcgtcgtt
    18721 cgcctggggt attcatttcg gcaaggcaag caggacaagt cgcggcatcg ggaacaattt
    18781 gcgtattcat gacgccaccc gcgctctggc ggatggtgaa ctcagtgggc agttgtgacc
    18841 agataaacgg ctcacgctcg acgctatcaa tacgcgccag tggcgggcag tgctgatgca
    18901 attgaacaag aaacgtttcc ggatcttcca gcagccggac ttctacgcca tcgccgtcat
    18961 tacagacatc gccgtgaaga tttaattgct gtgccagttg ccagacaaac ggacgaaaac
    19021 cgacgccctg cactttgcca cgaatacgca gttggacacc gcaagatgtg ttttttgcca
    19081 ttgagttatt cccgccatca tgaattgcgt aacccgccca gccggacacg agcgcgtcgc
    19141 atccggcaat cacaggtcgg cgataccgcc cgctccgtat tctacgaata tttccgggaa
    19201 ttcctttgat gccagaacag ttcagtaaga tttttagaac atcagcgccg tacggcgacg
    19261 tttttctgcg ctcagttgtt caagtttatt acgatcgaca caaatcagcg catgagtcgg
    19321 gcaagccgcc atacacgccg ggccgtcttc acgatggttg cacaggtcac atttattggc
    19381 ttcggctttg tcagcccgta cattcagccc cgcgccgctg ttgcgaatca ccggacgtac
    19441 caccacttcc atcgcgccat acgggcaagc cacaacgcag gttttgcaac caatgcaacg
    19501 ttcctgcatc acatgaacaa accctttatc acggctgata gcaccattcg ggcagacgtt
    19561 agcgcacggt gcatcttcac actgacggca gactgttgcc gtggaaatgt tcacaccttt
    19621 aatgacatgg attcgcggta aaaaagtttc cggggtcagc gatgcacagt cctgattctc
    19681 ctgatgagaa accacgcacg ccacttcaca ggtacggcaa ccaatacatt tactcgcgtc
    19741 agcaatgatg aaacggttca tcaaattctc cagcaatgac agttaatgcg ccgatacatt
    19801 cacaaatcat gccagttttt aatttactgt tatttaaaga aattaaattc tgtaatgcag
    19861 gaaaaacgat gtcatcgaca ctagtgacga tgacatgtga tgacaatgtt tattgcgaaa
    19921 gagcaatgag ggagccgcgg cggatcagtt ttccgctgaa ggttttcggc ggtgagaaat
    19981 ccccgccatc gagcataaaa atcagccgtc caataatttc ctgaatcatc tcagtcaccg
    20041 gaatttttac gctggagagc gccggaacgg tgtagggggc aatagcgata tcatcgaatc
    20101 cgataactga cacctgctct ggcaccgcta cgccgcgctc gtgtaacgct ttcatcgcac
    20161 ctatcgccat atcgtcgtta ctggcaacta acgcgctaaa tttagcccca cgttcgagca
    20221 acgtttctac cccttcggcc ccgctggcgg gcgtccattt accgttagcg ataagttttt
    20281 cattgagcgc aataccatgc tgcgccagcg cgtctttata cccggcaaga cgttcaacgc
    20341 tggtggggga atccatcgag ccggtaagga aagcaatctc ctgatgtccg gcgtttatca
    20401 actctgccac ggcgttaaag ctggtctgtt tatgatcgca ccagacgcta tggctgctgt
    20461 ttttgcgcag gcggcgatta agcaccatta tcggctgact gtgtgcgtca atgatgtcat
    20521 caatctcatc cacgcttaaa aaacgcgggt aaatcataat ggcgtcgcag cgcaaatcca
    20581 gcagatactg aatcgcctgg cgctcttctt cggcgctgtg tttaccatct gccaatagca
    20641 actgtcgccc tttctcttcc gccattcgcg cggcatgaaa cagtaattca ctaaaataaa
    20701 tgccgtggta aagcgtgttg gtcacgacca gccccagcgt ctgagtactc ttcgccgaca
    20761 gattgcgcgc cagcaagttt ggacggtaac cgctctcttc taccgcctga aacacgcgat
    20821 ctttagtctc ctggctgacg tagccattac ctgaaagcac gcgggaaacg gtcgcttttg
    20881 aaaccccggc gcgcttcgcc acttccagca tcgtcgtcat cattttcatc cctttacacg
    20941 caatcaacgc agtgtactgc accgtttgcc gattgtcctt gcgcaatcgg cgggaaaaat
    21001 attcaggtga ccggtttcac aaatataaaa aatgaacaat taactctctt gcttattcag
    21061 tgacaactat tcatgatttt gtgaaaccgg tttcctaatt ccgtttcagc atcggcattt
    21121 ttccgtcacg tcgactgata acaactacat ctaccctact gataacagga taaaatccga
    21181 tggccaaaaa ttatgcggcg ctggcacgct cggtgatagc ggcactgggc ggcgttaata
    21241 acatctcggc agtcacgcac tgtatgacgc gtttgcgctt tgttatcaaa gatgaccagc
    21301 ttatcgacag tccgacgttg aaaaccatct ccggcgtgct cggcgtggta cgtagtgaca
    21361 accagtgtca ggtgattatc ggcaataccg tttcacaagc ctttcaggaa gtcgtcagcc
    21421 tgctgccggg agatatgcag cccgcacagc ccgtgggtaa acccaaactt acgctacgtc
    21481 gcataggtgc ggggatcctc gatgcgctga tcggcaccat gtcaccgctg atcccggcga
    21541 ttatcggcgg atcgatggtc aaactgctgg cgatgatcct cgagatgagc ggcgtgctga
    21601 caaaaggatc gccgacctta accattctga atgtgattgg tgacggtgct ttcttcttcc
    21661 tgccgctgat ggtcgcggct tctgccgcca tcaaatttaa aaccaatatg tcgctggcga
    21721 ttgccatcgc gggtgtgctg gtacatccga gttttattga attaatggcg aaagcggccc
    21781 agggtgaaca tgtcgaattt gccctgattc cggtcaccgc ggtgaaatac acctacacgg
    21841 tgatcccggc gctggtgatg acctggtgcc tgtcatatat cgaacgctgg gtggacagca
    21901 ttacaccggc ggtgactaaa aacttcctca agccaatgct gattgtgttg attgccgcac
    21961 cgctggcaat tctgctgatt ggcccgattg gtatctggat cggtagcgcc atttcggcgc
    22021 tggtttacac cattcatggt tatctgggct ggctttcagt cgccattatg ggtgcgctgt
    22081 ggcctctgct ggtaatgacc gggatgcacc gcgtctttac gccaaccatc attcagacca
    22141 ttgccgaaac cggcaaagaa gggatggtca tgccgtcaga gatcggcgct aacctgtcgc
    22201 tgggcggttc atcactggcg gtggcgtgga aaacgaaaaa cccggaactg cgccagacgg
    22261 cgctggctgc ggcggcatca gccattatgg cggggatttc cgaaccggcg ttatatggcg
    22321 tggcgatccg cctgaaacgt ccgcttatcg ccagtcttat cagcggtttt atttgcggcg
    22381 cggttgccgg tatggcgggg cttgccagcc actcaatggc agcgccgggg ctatttacca
    22441 gcgtgcagtt cttcgagccg gcgaatccaa tgagcatcgt ctgggtgttc gcggtcatgg
    22501 cgctggcggt ggtgctgtcg ttcatcctca cactgttgct cggctttgag gatattcctg
    22561 ttgaggaagc gactgccgag gcgcgaaagc atcagagcgc acaaccgacc gtcgccaaag
    22621 aagtaagtct taattgagga tgaaaatgtc agtatttcca gaaggttttt tatggggcgg
    22681 cgcgcttgcc gccaaccagt ctgaaggtgc gtaccgtgaa ggtggcaaag ggctgaccac
    22741 cgtcgatatg atcccgcacg gcgagcatcg aatggcggtg aaactggggc tggaaaaacg
    22801 ttttcagttg cgcgatgacg agttttatcc cagccatgag gcgacggatt tttatcatcg
    22861 ttataaagaa gatatcgccc tgatggcaga gatgggattc aaagtgttcc gtacctcaat
    22921 tgcctggagc cgcctcttcc cgcagggcga tgaactgacg cccaaccagc agggcattgc
    22981 cttttaccgc gcggtatttg aagagtgtaa aaagtacggt atcgaaccgc tggtcacgtt
    23041 gtgccacttc gatgtgccga tgcatctggt caccgaatat ggctcctggc gtaaccgcaa
    23101 gctggtggag tttttcagcc gctacgcccg gacctgcttt gaagcatttg atggcctggt
    23161 gaaatactgg ctcaccttca atgaaatcaa cattatgttg catagcccgt tctccggcgc
    23221 gggtctggtg tttgaagaag gcgaaaatca ggatcaggtg aaatatcagg ctgcgcatca
    23281 ccaactgatt gccagtgcat tagccaccaa aatcgcccat gaggttaacc cgcaaaatca
    23341 ggtgggctgt atgctggcgg gcggtaactt ctacccttac agttgcaagc cggaagatgt
    23401 ctgggcggcg ctggagaaag atcgggaaaa cctgtttttt atcgatgtgc aggcgcgggg
    23461 cgcgtatccg gcttactctg cccgcgtatt ccgcgaaaaa ggggtaacca tcgacaaagc
    23521 accgggcgat gatgagatcc tgaaaaacac cgtcgatttt gtctctttca gctattacgc
    23581 ctcacgctgc gcctcggcgg agatgaacgc caacaatagc agtgcggcga acgtagtgaa
    23641 atcgctgcgt aacccgtatc tgcaagtgag cgactggggc tggggtattg atccactcgg
    23701 tctgcgtatc accatgaaca tgatgtacga ccgctatcag aagccgctgt ttctggtgga
    23761 aaacggcctg ggcgcaaaag atgaatttgc ggccaatggt gagattaacg atgactatcg
    23821 catcagctat ttacgcgaac atatccgcgc aatgggcgaa gcgattgcag atggcattcc
    23881 gctgatgggc tacaccacat ggggctgtat tgatttagtt tccgcctcta cgggtgaaat
    23941 gagcaaacgc tacggttttg tctttgttga ccgtgacgac gcaggcaacg gtacgctgac
    24001 gcgcacgcgt aagaaatcgt tctggtggta taaaaaagtg attgccagta atggtgagga
    24061 tttagagtaa gtaactaccg tcgcacgaac caggaaagcc cgataagcgt tgcgcatcgg
    24121 gcaatcttgg gtttggcatc agtcaaaatc aaagaaacca ttccggctta acaccaaatc
    24181 gggctgaaag tgccttaatg tgggatatcg tcagggatcg ttgcccagac aaaatctgac
    24241 tgaccaggga tttagagccg atttcgttct tcaaatccgc gtaggtcaga ttatgttgat
    24301 caatcagcgt acgaagtaac gccacgccaa ccggcattgc tgcaacggct ttgtcgaact
    24361 cggcaaactt ttcgttgttg ttttcatatt ctgcaatgcg gctcgccaga aagtcgataa
    24421 gtggattggt gtcatcttct tcaatcaaat attcgaccag ttccagtgct tcacgataat
    24481 catcttctga gtcactacct cccagaaagg ggactgcatt gaccagttct cttgttgctt
    24541 taacagcgcg tgcagcatta gcagtcattc tttgttctct ctgtagtaac gtgtcagttt
    24601 gtcatactct gcgtgattcg ttatgtgctt cacaaagaac cgcttattaa caaagtttat
    24661 gtaggcaata accctaagat tgttcccgcc gacatccaga acgtaccatt tgttgcgata
    24721 tctaaaattg tcgaggttgg gaaacgccgt tcgcatttct tctggtgtag aaaaatccgt
    24781 ttccttaata acccgataca atgagtatag agccagagcg tcgttaggat atttgcgcgc
    24841 acactcttca aatggcgctt tcgaaatgat gtgcatttta acttccttat tagcgcctga
    24901 atgactaaac ctggactacc attccttcgg atttattttc ctatagtagt tgatcacacg
    24961 ggtgttcaca atatgtaaac acccgtctac acgtcacaat tgcacgtcca aattccaaaa
    25021 cgtgaacatg tttgtctacg aactactctt cttccaccgc taactgcgcg aatccgccat
    25081 tcccttccca gccttccagt cgttgataaa cggtttctac cgcatcttta atcggctggg
    25141 tcatcgggta gtaaaagccg acgatatccg gctggatgcc gaggaaaatc acttcgccaa
    25201 tgtcttcttt taactggtcg ataaggtagt tcaacggcat gttatgggta gtcatcataa
    25261 acatctcggc gatatcatcc ggatcgatga tgcggatctc gccggggttt agccccatat
    25321 ccgtggcgtc gacaatcagc agtcgtgtcg ggcgcagttc gcgaatagcg acaatgtcgt
    25381 tttccggtgc gctaccgccg tcaatcacca cccagttacc tttcggcgcg gcggcgcact
    25441 tttccgccag cagcggacct gcgccatcat cgcccatcat gctattgcca acacagagta
    25501 aaacgtcagt cacgcaatct cctcaccatc aaatagatgg cgttttcctg atgaatatca
    25561 tgcagcatac ttaacagcat tgtactccat tccttctgct gcgaagtttg cgcagcccgg
    25621 gctttatcga atgcgttggc cagcatcggc acatggttaa tgtcgatgac gatctcacca
    25681 tatttcggca cgccttccat tttgcggcgg gcttcgctgc ccgcctccag agtggcaatc
    25741 catgccagat attcatccca cggacaggtg agcgccgctt ccaggcaatc gataacccca
    25801 aggtggtgac caatcgccag gctgtaatag accacctgct gcgcctcggc gggcgtggca
    25861 tcgttctcat caataaattt acggctcagt tgactgaaca ccaccttttc actcatcgga
    25921 tacgcgcctc ttcaacaaca tgattcagat ggctgacaat ctcgttcaga cgcggatcgt
    25981 tttccgcttc cagccagcgt gcaacctgct cttcgccctg ccctaactgt gtcaggaagt
    26041 catcggcaat ctggcgaccg taacggtaac ccgccaggcg gcgagcttcg cgatccactt
    26101 tcacgcgcag cggctgcacc atatcgccat gcaggatctc cgccggttgt tcatcctgct
    26161 cacccggccc acgggcgtga attttctgct ccagcaggcc gagcgccatt gcaaagccgt
    26221 acagcgtggc ggcaggcgtt ggcgggcagc cagggatata aacatccacc gggacgattt
    26281 tatccgtacc gccccacacg cagtagagat cgtggaagat cccgccgctg ttaccgcagg
    26341 caccgtagga gatacaaatt ttcgggtccg gcgcggactg ccacgcacgc agcgcagggg
    26401 atcgcattgc acgggtgacc gcgccggtaa acagtaaaat atccgcatga cgcggtgaag
    26461 gaacgacttt aatgccgaag cgttctgcat caaacagcgg cgaaagcgtg gcgaaaattt
    26521 cgatttcgca gccgttgcag ccgccgcagt ccacgcggta aacgtaggca gaacgtttga
    26581 tttttttcag taacgacgcc ttcatgctgg cgatggattc atccaccgtc atcgggaccg
    26641 gaatgccgtt ggcgtcacgg gggcctaata aattgctcat cagatggcct ctttcatatg
    26701 gcgagtcagt tcaatacggt cggacggcac caggcatttc tggcgcttac attccgggca
    26761 agtctcaaag ctttcgcggt ggttttccgc gcggctgtcg ccgttgtgct tgagcagcgc
    26821 aatggcgtag tcgatctctt tctggacggc gaaaggacga ttgcagacgc gacagttgca
    26881 cagcgcgaag cgggactgtt gcaggaagtc ttctttcttc cacaccgcca gttcgtactc
    26941 ttgcgacagc ttaatcgccg ccgtcgggca aacttcttcg cagcgtccac agaagatgca
    27001 gcgcccgaga ttaaactccc aggcaagctc tcctgtggcg aggtcagttt caaccgttaa
    27061 ggcgtttgac gggcaggcat tgacgcaggc cgcgcagccg atgcactgct gcgggttctg
    27121 ctctggctta ccacggaagt ttttatcaac cgcaatcggc tccagcggat aagacgaggt
    27181 cgccgtgccg gttttgataa cttttttgat aaaggtaaac atggcgattc cttatttcag
    27241 cggcgagttt ttacgctcaa tgctgtaacg ctcgagttct ttgtacggca ccactttgct
    27301 cttcttctta cgcacatcga ccacggtcat gcggtcggta caggagtagc aagggtccag
    27361 gctaccgata atcagcggcg catcggaaac ggtgttgccg cgcagcatgt agcgcagggt
    27421 cggccagttc gcgtaggtcg cggcacggca gcgccagcgg tacagcttct ggttgtcgcc
    27481 ggtcatgctc cagtggatat cgtcgccgcg cggcgcttcg gcaaagccca gcgcaaaacg
    27541 gtgcggaata taggtaaagc cttccaccat cagcggaccg cccggcaggt tatccagacc
    27601 gtagtcgatc atgttcagcg cggtatagac ctcgttgata cgcactttca gacgggaaat
    27661 aacgtcgcag ccctgctcgc tgtggacttc cattggcagc aggccataac caacaaacgg
    27721 gtgatcggca cgggtatcgc gggcgtgacc gctggcgcgg accatcgggc caacgttact
    27781 gaaatcgcgg gcgatttccg ggtccagacg accaatgccg acagtacgct gttccatgtt
    27841 cggtgtgctc agcagcacat ccaccagctc ctgcacttca cgacgcatct gttgcgccaa
    27901 ctggcgggtc tggatcatgt catctttcag cagatcgcga cgaattccgc cgatcaggtt
    27961 caggccgtag gttttacgcg caccggtaag gatctctgcc attttcatgg aggtttcacg
    28021 cacgcggaag aactgcataa agccggagtc gaagccggta aagtgactgg cgaggccgag
    28081 gttgagcaga tgcgagtgca ggcgttctac ctccagcaga atggcgcgga tcatctgcgc
    28141 acgttctggc acctgaatac ccatcgcgtt ttccaccgac gtggtgtagg cggtgctgtg
    28201 agcaaagccg cagatcccgc acacacggtc agagaggaag gtcacttcgt tgtaacccat
    28261 gcgggtttcc gccagttttt ccatgccgcg atggacatag aacaggcggt agtcggcgtc
    28321 gataatgttt tcgccatcga cgaacagacg gaagtgaccc ggttcgtcgg aagtgacgtg
    28381 cagcggacca atcggcacga cgttgttttt cttgtcgccc agttcgttga tgaactcgta
    28441 ggtttcagca tcggtagtcg gtgccggacg ttgacgataa tccatgctgt ctttacgcag
    28501 cggataaagt tcatccggcc agtcatccgg cagcaccaga cgacgttcat ccggcagccc
    28561 taccggaatc aaaccgtaca tatcgcgcac ttcacgctcg ccccataccg ccgccggaac
    28621 gcgcggcgtt acggacggat attccggttt gttggcgtca acttcaacgc gcacggttat
    28681 ccagcatttg gtgcccttct ccatcgacag cacgtagtaa acggcgtaat gaccattaag
    28741 tttgcgttcg tcgttaccaa acagcaccga cagccagccc ccctgcttgt agtagagaaa
    28801 ctccaccact tccggcaggt agttcacctt cacggtcacg gtcagctgat ctttggtctg
    28861 ccaggcgtgg tccagcacga cgcccggaaa tgcctcattc agcgcagcga gataatgttg
    28921 acctaatttt tcttcagaca tgctcaaact ctctttaatc acgccgccag caaggagacg
    28981 aacgctaaaa atgcaaagcc aaacccagcc caggtaatgc gcggagtaat atcaagacgc
    29041 agacgggcca tgctgttttc gaacagcgcg ataaccagga cgccaaccac cagtttgacg
    29101 atggcaatca ccagcgccag cagcagccca ccgacggtga aggtttccat ttgtccccac
    29161 ggaataaaca ccccgacgaa catctgcaac accaccagct gtttcaggct gataccccat
    29221 ttcatgacgc caaagccgct gccgctatac tcagagagcg gaccttcctg caactcctgc
    29281 tcggcttccg ccaggtcgaa cggcagtttg cccatttcga taaaggtggc gaatgcacag
    29341 gcacaaagcg ccagcaccag cggaatgctc tggctcagcg gccagtgata aacggtgtcg
    29401 gtgatgttgc tgatgttggt ggaaccggca acctgtgcgg cgacccacag accaagcagc
    29461 agcatcggtt caaccagcac gccaagcatc gcttcacggc tcgcgccgat agcggtaaac
    29521 gggctaccgg tatccagacc agaaatggca aagaagaaac gcgcgatggc aaagagatac
    29581 agtaaagtga tcaaatcgcc cagctgcggc agcggagaac caacggtcac caccggcagc
    29641 gcagtagcga tagtcagcat gacgcccacc atcacatacg gcgtcaggcg gaacacccag
    29701 ccggaggcat ccgggccaac gctctggcga cccagcagtt tgataatgtc gcgatactcc
    29761 tgcaacacgc ccggcccgcg acggttatgc aagcgggcgc gcgccacgcg ggttataccg
    29821 gagagcagcg gcgcaacggc aaataacacc agcgcctgaa ttaacggata taaaacactc
    29881 attctcaggc tcctcgtgaa acaataatca ccaccagcac cgccagttca accagcgcca
    29941 tccggcggaa cagcaacgca ctgccttcgc actgccagcc cggcaccagc gacaccggat
    30001 tcagccattt gcgcagtttc agcactggcg caaacgcctg tttcaccggc atggcaaaac
    30061 cgtgagcggt aatcaccatt gatttttcgt ggtcgtagcc gcacacccag gccgcgccgc
    30121 gggaacgcga cggcaaacgg tcgcctttgc aaatcgccat aatgatgaat ggcagcagcg
    30181 ggcaggcaat cagcagcaac gtgatcatgg gttgagaaac ggtggtgtta gcaggctcca
    30241 gcggcagagg tacagcagca gagagcatcg gcagcagcca cggcgcagca acaccgccaa
    30301 ttacgcagca aatcgccagt gccactacgc ttacgctcat caggagcggc gcacaggtgg
    30361 cgttttcggc ttctttggta cgcggcgcgc cgaggaacgt gacgccatag actttcgcca
    30421 tacacatcac cgctagcgca ccggtaattg ccagacccac tgcgagcagc ggccccagca
    30481 gacgggcaac aaacgcgcca ctattgctca gtttgaagaa ggattgatag ataacccatt
    30541 ccccggcaaa cccgttcagc ggcggcaacg cagccattgc catcagccca actaacatgg
    30601 cgatggagat aaccggcatt ttcttgccaa taccaccgag tttttcgata tcgcgatgac
    30661 cggtacggaa ccagacgctc cccgccccga ggaaaagtac gcttttgaac aggctatggt
    30721 taagcagatg gtacagacca ccgaccaggc caagagcaat cagcgccggt tgttcgagcg
    30781 cgatacccgt tacgccagcg cccagcccca gcaggataat gccgatattt tccagggtgt
    30841 ggtaagccag caggcgctgg atgttgtgtt ccatcaacgc atacagacca ccgacgaacg
    30901 cggtgatcat gccgagcacc agcagcgcga ttccccacca cagcggtgca ttaccgccca
    30961 gcagtgacag ggttaaaatg cccagcaggc caattttcat gactaccgtg gaaaacaacg
    31021 cggcagctgg cgcagaggcg ttagcatgtg cctgcggcac ccagccgtgc agcggaataa
    31081 tcccggccag caggccaaag ccaatcacac cgagcagcca gatatcggaa ccgagcggca
    31141 gctgttgcat acgcatatcc agcaggcgca gatccagcgt gccgtaacgc tgccacagca
    31201 gccagcaagc aatcgccagc agcagagtgc caagacgccc cagtgcaaac cacagtttgc
    31261 cctctttgct gttgttggtg aggaacaccg cgcacaaggc catgatttct gccattacca
    31321 cgaacatacc gaggttgctg gcgatgacag cacagacggc agcagccatc aacatattga
    31381 tctgcaagcc gttgcacttc acctgcgcgt ggcgatgcca gtcaatgttg tagaggctga
    31441 caaacagacc gcacaggccg agcgtaatca gccaaatcgc gttaagcgga gagatttgca
    31501 catcgtagct tactagcgac agcgcaccgc tcacgccaac cgcgccagtc agtacagtga
    31561 agcccgcggc tgccgtatac agactaccca ccgcgccgcc aattccggct atccagccgc
    31621 ttagcgcctt ttgaaaagaa aagagaaatg ccagaacagc ggcggcgaca aaccacgcca
    31681 cgccgctatt gatcagggaa attgcgctca tttagcctct ccactttgag cctgctgaaa
    31741 caaggtgaga tcgccaaagt ccgtgttaaa ggtcagctca cgcttacgtt tgctgacgcg
    31801 ggcgatatcg gtgttatcca ccagatgcag ggctttagtc gggcacatcc gcacgcaggc
    31861 cggaccttgt tcatcaaagc tacaaaggtc acatttgacg gcgatcgcgc gaatacctgg
    31921 cacccagtca agcaatgtgc tgacacgcgc cggagcaggc ggtgccggtg gcgctttcgg
    31981 ggtattggcg tttgccggaa tatccagcgg acggctgccg gaaaattcaa ttgcgccaaa
    32041 cgggcaggcg atgccgcata gtttgcagct tacgcacagg ctttcattca actgcacggc
    32101 cccatcaacg cgggtgatgg cgttaaccgg gcagaccacc gcacagggcg catcttcaca
    32161 gtggtgacag agctgcggcg cagattcttt ttcattgagc atcactcgca ggcgcggcat
    32221 tgattgcagg ccgtgctggc gatgcgtctc tgaacaggcg gcctcacagg tgtggcagcc
    32281 gatacagagc gtggagtcag caattacaaa acgattcacc aggcattcct caggtgattg
    32341 tcatttttga cgaaaacatg ccgatgaaat gtcattttcg acactcatcg acacgcccat
    32401 ccccaaacag gcgtaacgcc tgcaaaacgg gcaaagcctc agctcatgct gccgggcttt
    32461 gtccctttac cagttggctt aaattcaccg gcacattgtt ttcaatggcg gtgtataagc
    32521 tgtcgtaaac gccagcgatt ttttcgagat agtgttccag aacctgttcg cgatcgcgga
    32581 tgttgacctt gccatcaatc atgccgtcaa tgctcagttg cgcctgcgca atccgctgtt
    32641 tgtcttcacc atcttttgtt tcgacgtaat actcgatggt gtggctgtta aagccatccg
    32701 ccagggtgac gtaaatgcga aaatgttcaa aaaggacgaa acagagttct ttgtccggcg
    32761 cgcagctcat ggcgtgatgc aggcgcgctt tcgataacgt gatcccctga accagcgaat
    32821 tgcagtagat gtgccactgg tcctgtaggc gacgatgccg ctgtgcgatg taatcggctt
    32881 tctcgcttat ttcccaaata gtcattgtca ggttacccgt ttaacagaga tgccagcttt
    32941 aagcattttt tgtgccaact tttaatttat tgttattaaa gcgattttta agctaaagat
    33001 gaatttcgtc gccgtgtcga cgtgtcattt cgacatcatc gacattattc accgcaggga
    33061 taatcaacac tggcacaatt attgcttgta gctggcaata gttaatggga ggcgatatgc
    33121 acgaaataac cctctgccaa cgggcactgg aattgatcga acagcaggcc gcaaaacacg
    33181 gcgcaaaacg cgtaactggg gtctggctca aaattggcgc attttcttgt gtcgaaacca
    33241 gctctcttgc cttttgtttt gatctggttt gccgcggcag cgtggcggaa ggttgtaaac
    33301 tgcacctcga agaacaagag gccgaatgct ggtgtgaaac atgccaacag tatgtgacgc
    33361 tactgaccca gcgcgtccgc cgctgtccac agtgtcatgg tgacatgcta cagattgtgg
    33421 cagacgacgg tttacagatt cggcggatag aaatagacca ggagtgagcg atgtgtacaa
    33481 catgcggttg cggtgaaggc aacctgtata tcgagggtga tgaacataac cctcattccg
    33541 cgtttcgtag cgcgccattt gccccggcgg cacgcccgaa gatgaaaatc accggcatta
    33601 aaacgcctga atttaccccc agccagactg aagaaggcga cctgcattac ggtcatggcg
    33661 aagcgggcac tcacgcgccg ggcatgagcc agcgtcggat gctggaagtc gaaattgacg
    33721 tgctggacaa aaataaccgt ctggctgaac gcaaccgcgc gcgctttgct gcccgcaagc
    33781 aactggtgct caacctggtt tccagccctg gttccggtaa aaccaccctg ctgacggaaa
    33841 ccttaatgcg cctgaaagac agcgttccgt gcgcggttat tgaaggcgat cagcaaaccg
    33901 tgaacgatgc cgcacgcatt cgcgctaccg gcacaccagc gattcaggtg aataccggta
    33961 aaggctgcca tcttgacgca cagatgattg ccgacgccgc accgcgcctg ccactggacg
    34021 ataacggtat tctgtttatc gaaaacgtcg gcaacctcgt gtgcccggcc agcttcgatc
    34081 tcggtgaaaa acacaaagtg gcggtgcttt ccgttaccga aggtgaagac aaaccgctga
    34141 aatatccgca tatgtttgcc gcagcttcgc tgatgctgct caacaaagtt gacttgctgc
    34201 cgtatctcaa ctttgacgtt gagaagtgca tcgcctgcgc ccgcgaagtc aatccagaaa
    34261 ttgaaatcat ccttatttcc gccaccagcg gcgaagggat ggaccagtgg ctgaactggc
    34321 tggagacaca gcgatgtgca taggcgttcc cggccagatc cgcaccattg acggcaacca
    34381 ggcgaaagtc gacgtctgcg gcattcagcg cgatgtcgat ttaacgttag tcggcagctg
    34441 cgatgaaaac ggtcagccgc gcgtgggcca gtgggtactg gttcacgttg gctttgccat
    34501 gagcgtaatt aatgaagccg aagcgcgcga cactctcgac gccttacaaa acatgtttga
    34561 cgttgagccg gatgtcggtg cgctgttgta tggcgaggaa aaataatgcg ttttgttgat
    34621 gaatatcgct cgccggaaca ggtgatgcag ttaattgagc atctgcgcga acgtgcttca
    34681 catctctctt acaccgccga acgccctctg cggattatgg aagtgtgcgg tggtcatacc
    34741 cacgccattt ttaaattcgg cctcgaccag ttgctgccgg aaaacgttga gtttatccac
    34801 ggtcccggtt gcccggtgtg tgtactgccg atgggtagaa tcgacacctg cgtggagatt
    34861 gccagccatc cggaagtcat cttctgtacc tttggcgacg ccatgcgcgt gccggggaaa
    34921 cagggatcgc tgttgcaggc aaaagcacgc ggtgccgatg tgcgcatcgt ttactcgccg
    34981 atggatgcgt tgaaactggc gcaggagaat ccaacccgca aagtggtgtt cttcggctta
    35041 ggttttgaaa ccaccatgcc gacgacggcc atcactctgc aacaggcgaa agcgcgtgat
    35101 gtgcagaatt tttacttctt ctgccagcat attacgctta tcccgacgct gcgcagtttg
    35161 ctggaagagc cggataacgg tatcgacgcg tttcttgcgc ccggtcacgt tagtatggtt
    35221 atcggcactg atgcctataa ttttatcgcc agcgattttc atcgtccgct ggtggtcgct
    35281 ggtttcgaac cccttgatct actgcaaggc gtggtcatgc tggtggagca gaaaatagcg
    35341 gcccacagca aggtagagaa tcagtatcgt cgggtggtgc cggatgccgg taacctgctg
    35401 gcgcaacagg cgattgccga tgtgttctgt gtcaacggcg acagcgaatg gcgcggctta
    35461 ggcgtgattg aatcttctgg tgtacacctg acgccggatt atcaacgatt cgatgccgaa
    35521 gcgcatttcc gcccggcacc gcagcaggtc tgcgatgacc cgcgcgcacg ttgtggcgaa
    35581 gtattaacgg gcaaatgtaa gccgcatcaa tgcccgctgt ttggtaacac ctgtaatcct
    35641 caaaccgcgt ttggtgcgct gatggtttcc tccgaaggag cgtgcgccgc gtggtatcag
    35701 tatcgtcagc aggagagtga agcgtgaata atatccaact cgcccacggt agcggcggcc
    35761 aggcgatgca gcaattaatc aacagcctgt ttatggaagc ctttgccaac ccgtggctgg
    35821 cagagcagga agatcaggcc cgtcttgatc tggcgcagct ggtagcggaa ggcgaccgtc
    35881 tggcgttctc caccgacagt tacgtcattg acccgctgtt ctttcctggc ggtaatatcg
    35941 gcaagctggc gatttgcggc accgcgaatg acgtagcggt cagtggcgct attccgcgct
    36001 atctctcctg tggctttatc ctcgaagaag gattgccgat ggagacactg aaagccgtag
    36061 tgaccagcat ggcagaaacc gcccgcgcgg caggcattgc catcgtcact ggcgatacta
    36121 aagtggtgca gcgcggcgcg gcagataaac tgtttatcaa caccgctggc atgggcgcaa
    36181 ttccggcgaa tattcactgg ggcgcacaga cgctaaccgc aggcgatgta ttgctggtta
    36241 gcggtacact cggcgaccac ggggcgacta tccttaacct gcgtgagcag ctggggctgg
    36301 atggcgaact ggtcagcgac tgcgcggtgc tgacgccgct tattcagacg ctgcgtgaca
    36361 ttcccggcgt gaaagcgctg cgtgatgcca cccgtggtgg tgtgaacgcg gtagttcatg
    36421 agttcgcggc agcctgcggt tgcggtattg aaatttcaga agcggcactg ccggttaaac
    36481 ctgctgtgcg cggcgttacc gaactgctgg gactggacgc ccttaacttt gccaacgaag
    36541 gcaaactggt gatcgccgtt gaacgcaacg cggcagagca agtgctggca gcgttacatt
    36601 cccatccact gggaaaagac gcggcgctga ttggtgaagt ggtggaacgt aaaggtgttc
    36661 gtcttgccgg tctgtatggc gtgaaacgaa ccctcgatct accgcacgcc gaaccgcttc
    36721 cgcgtatatg ctaataaaat tctaaatctc ctatagttag tcaatgacct tttgcaccgc
    36781 tttgcggtgc tttcctggaa gaacaaaatg tcatatacac cgatgagtga tctcggacaa
    36841 caagggttgt tcgacatcac tcggacacta ttgcagcagc ccgatctggc ctcgctgtgt
    36901 gaggctcttt cgcaactggt aaagcgttct gcgctcgccg acaacgcggc tattgtgttg
    36961 tggcaagcgc agactcaacg tgcgtcttat tacgcatcgc gtgaaaaaga cacccccatt
    37021 aaatatgaag acgaaactgt tctggcacac ggtccggtac gcagcatttt gtcgcgccct
    37081 gatacgctgc attgcagtta cgaagaattt tgtgaaacct ggccgcagct ggccgcaggt
    37141 gggctatacc ccaaatttgg tcactattgc ctgatgccac tggcggcgga agggcatatt
    37201 tttggtggct gtgaatttat tcgttatgac gatcgcccct ggagcgaaaa agagttcaat
    37261 cgtctgcaaa catttacgca gatcgtttct gtcgtcaccg aacaaatcca gagccgcgtc
    37321 gtcaataatg tcgactatga gttgttatgc cgggagcgcg ataacttccg catcctggtt
    37381 gccattacca acgcggtgct ttcccgcctg gatatggacg aactggtcag cgaagtcgcc
    37441 aaagaaatcc attactactt cgacattgac gatatcagca tcgtcttacg cagccaccgt
    37501 aaaaacaaac tcaacatcta ctccactcac tatcttgata aacagcatcc cgcccacgaa
    37561 cagagcgaag tcgatgaagc cggaaccctc accgaacgcg tgttcaaaag taaagagatg
    37621 ttgttgatta atctccacga gcgggacgat ttagccccct atgaacgcat gttgttcgac
    37681 acctggggca accagattca aaccttgtgc ctgttaccgc tgatgtctgg caacaccatg
    37741 ctgggcgtgc tgaaactggc gcaatgcgaa gagaaagtat ttaccactac caatctgagc
    37801 ttactgcgcc agattgccga acgtgtggca atcgctgtcg ataacgccct cgcctatcag
    37861 gaaattcatc gtctgaaaga acggctggtt gatgaaaacc tcgccctgac cgagcagctc
    37921 aacaatgttg atagtgaatt tggcgagatt attggccgca gcgaagccat gtacagcgta
    37981 cttaaacaag ttgaaatggt ggcgcaaagt gacagtaccg tgctgatcct cggtgaaact
    38041 ggcacgggta aagagctgat tgcccgtgct atccataatc tcagtgggcg taataatcgc
    38101 cgcatggtca aaatgaactg cgcggcaatg cctgccggat tgctggagag cgatctgttt
    38161 ggtcatgagc gtggggcttt taccggtgcc agcgcccagc gtatcggtcg ttttgaactg
    38221 gcggataaaa gctccctgtt cctcgacgaa gtgggcgata tgccactgga gttacagccg
    38281 aagttgctgc gtgtattaca ggaacaggag tttgaacgtc tcggcagcaa caaaatcatt
    38341 cagacggacg tgcgtctaat cgccgcaact aaccgcgatc tgaaaaaaat ggtcgccgac
    38401 cgtgagttcc gtagcgatct ctattaccgc ctgaatgtat tcccgatcca cctgccgcca
    38461 ctacgcgagc gtccggaaga tattccgctg ctggcgaaag cctttacctt caaaattgcc
    38521 cgtcgtctgg ggcgcaatat cgacagcatt cctgcggaga cgctgcgcac cttgagcaac
    38581 atggagtggc cgggtaacgt acgcgaactg gaaaatgtca ttgagcgcgc ggtattgcta
    38641 acacgcggca acgtgctgca gctgtcattg cctgatattg ctttaccgga gcctgaaacg
    38701 ccgcctgccg caacggttgt cgcccaagag ggcgaagatg aatatcagtt gattgttcgc
    38761 gtgctgaaag aaaccaacgg cgtggttgcc gggcctaaag gcgctgcgca acgtctgggg
    38821 ctgaaacgca cgaccctgct gtcacggatg aagcggcttg gaattgataa atcggcattg
    38881 atttaacaga tgtggttata ctcgatcaac attcaatgaa aggaggcagt atggcagttt
    38941 cagcaagaaa tcaattaacc ggaacagtta gcgcagtagc aatgggcgct gtgaatgatg
    39001 aagtagaact gacgctggca ggtggtgcaa agctggtggc aattgtgact cacagcagcc
    39061 agcaagcgct gggtctggcg aaagggaaag aagcgattgc cctgattaaa gccccgtggg
    39121 taacgctggc aacggaaggc tgtggactga aattctctgc tcgcaaccag tttgctggca
    39181 gcgtgtcgac aatcaccgaa ggcgcagtga acgccactgt ccatatcaaa acggatgcgg
    39241 gttttgaaat tgtggcagtg gtaacaaatg aaagtcagga tgaaatgaaa ctcaccactg
    39301 gctcgcgcgt tattgcattg atcaaagcat cagccatcct gattgccacc aaagcgtaaa
    39361 cgccttattt gccggagagt atggctctcc ggcagattta tttctttgga cgatattttt
    39421 ctggcaactc cggcaccgga cgcttgtcat cgatgagatg acgcacggtt aagatcggat
    39481 gacgccacag cattctcggc ccggcccaac gcataatctg tttcatctct tcacgctttg
    39541 caggctggta acagtgcacc ggacactgct tacaggctgg tttctcttcg ccgaacacac
    39601 atttatccag ccgcttttgc gcgtaggcaa acagcgcgtc gtaatgctcc ggctccgctg
    39661 acgcctgcgg gcatttcgct tgataaagat cgatcatttt tttaatcgtc agtttttcac
    39721 gagagatacg cttgccggac atgctgcctc catactctta aggtgtattt atattacaac
    39781 ttaatttgaa aggggactat ggctctgaag gaggaggttt attcaaccga cgcaattttg
    39841 cgtacctgct tcataagcat cacgcaaaag ctgcaaaaca gcatctttcc cggaatcacc
    39901 atcaagaact cgccgttcgc ttcttcccct gaaatgatta actccggtat catgtgcgcc
    39961 ttatgtgatt acaacgaaaa taaaaaccat cacacctcat ttaatatcag ggaaccggac
    40021 ataaccccat gagtgcaata gaaaatttcg atgcccatac gcccatgatg cagcagtatc
    40081 tcaagctgaa agcccagcat cccgagatcc tgctgtttta ccggatgggt gatttttatg
    40141 aactgtttta tgacgacgca aaacgcgcgt cgcaactgct ggatatttca ctgaccaaac
    40201 gcggtgcttc ggcgggagag ccgatcccga tggcggggat cccctaccat gcggtggaaa
    40261 actacctcgc caaactggtg aatcagggcg agtccgttgc catctgcgaa caaattggcg
    40321 atccagcgac cagcaaaggt ccggttgagc gcaaagttgt gcgtatcgtt acgccgggca
    40381 ccatcagcga tgaagcgctg ttgcaggagc gtcaggataa cctgctggcg gctatctggc
    40441 aggacagcaa aggtttcggc tacgcgacgc tggatatcag ttccgggcgt tttcgcctga
    40501 gcgaaccggc tgaccgcgaa acgatggcgg cagagctgca acgcactaat ccggcagagc
    40561 tgttgtatgc agaaaatttc gccgagatgt cgctgattga aggtcgtcgc ggactgcgcc
    40621 gtcgcccgct gtgggagttt gaaatcgaca ccgcgcgcca gcagttgaat ctgcaatttg
    40681 gcacccgcga tctggtcggt tttggcgtcg agaacgcgcc gcgcggactt tgtgctgccg
    40741 gttgtctgtt gcagtatgcg aaagatactc aacgcacgac cctgccgcat attcgttcta
    40801 tcaccatgga acgtgagcag gacagcatca ttatggatgc cgcgacgcgt cgtaacctgg
    40861 aaattaccca gaacctggcg ggcggtgcgg aaaatacgct ggcttctgtg ctcgactgca
    40921 ccgtcacgcc gatgggcagc cgtatgctga aacgctggct gcatatgcca gtgcgcgata
    40981 cccgcgtctt gcttgagcgc cagcaaacta ttggcgcatt gcaggatttc accgccgagc
    41041 tgcagccggt actgcgtcag gtcggcgacc tggaacgtat tctggcgcgt ctggctttac
    41101 gaactgctcg cccacgcgat ctggcccgta tgcgtcacgc tttccagcaa ctgccggagc
    41161 tgcgcgcgca gttagaaaat gtcgatagcg ctccggtaca ggcgctgcgt gaaaaaatgg
    41221 gcgagtttgc cgagctgcgc gatctgctgg agcgagcaat catcgacaca ccgccggtgc
    41281 tggtacgcga cggtggtgtt atcgcaccgg gctataacga agagctggat gagtggcgcg
    41341 cgctggctga cggcgcgacc gattatctgg agcgtctgga agtccgcgag cgtgaacgta
    41401 ctggcctgga caccctgaaa gtcggcttta acgcggttca tggttattac attcagatca
    41461 gccgtggaca aagccatctg gcacccatca attacatgcg tcgccagacg ctgaaaaacg
    41521 ccgagcgcta cattattcca gagctaaaag agtacgaaga caaagttctc acttcaaaag
    41581 gcaaagcact ggcactggaa aaacagcttt atgaagagct gttcgacctg ctgttgccgc
    41641 atctggaagc gttgcaacag agcgcgagcg cactggcgga actcgacgtg ctggtgaacc
    41701 tggcggaacg ggcctatacc ctgaactaca cctgcccgac ctttattgat aaaccgggta
    41761 ttcgcatcac cgaaggccgc catccggtgg ttgaacaggt gctgaatgag ccgtttatcg
    41821 ccaacccgct gaacctgtcg ccgcagcgtc gcatgttgat cattaccggt ccgaatatgg
    41881 gcggtaaaag tacctatatg cgccagaccg cactgattgc gctgatggcc tacatcggca
    41941 gctatgtacc ggcacaaaaa gtcgagattg gacctatcga tcgcatcttt acccgcgtag
    42001 gggcagcgga tgatctggca tccgggcgtt caacctttat ggtggaaatg accgaaaccg
    42061 ccaatatttt acataacgcc accgagtaca gtctggtact gatggatgag attgggcgcg
    42121 ggacgtccac ttacgatggt ctgtcgctgg cgtgggcgtg cgcggaaaat ctggcgaata
    42181 agattaaagc gttgacgttg tttgccaccc actatttcga gctgacccag ttaccggaga
    42241 aaatggaagg cgtcgccaac gttcatctcg atgcactgga gcacggcgac accattgcct
    42301 ttatgcacag cgtgcaggat ggcgcggcga gcaaaagcta cggcctggcg gttgcagccc
    42361 ttgcgggcgt gccaaaagag gtgatcaaac gcgcgcggca gaaactgcgt gagctggaga
    42421 gcatttcgcc gaatgccgcc gcgacgcagg tagatggcac gcagatgtct ttgctgtccg
    42481 taccagaaga aacttcgcct gcggtcgagg cactggaaaa cctcgacccg gattcactga
    42541 ctccgcgtca ggcgctggag tggatttatc gcttgaagag tctggtgtaa taacaattcc
    42601 cgatagtctt ttgctatcgg gaatattaac gacaactgac gaatcaaata aaaacaccct
    42661 gtataatagg aaatcttatt ttacagggta aaaccatgcc atctacacgc tatcaaaaaa
    42721 ttaatgccca tcactatcgt tatatatggg ccgttggtga tattcatggt gactatcaat
    42781 tattacaatc ccgcttacat caactctctt ttttccctga aaccgactta cttatttctg
    42841 tcggcgataa tattgatcgt gggccggaga gtcttaacgt actacgcctg ttaaaccagc
    42901 cctggtttac atcggttaaa ggcaaccatg aagcgatggc gcttgatgca ttcgaaactg
    42961 gcgatggaaa tatgtggctt gccagcggcg gcgactggtt ctttgaatta aatgagacgg
    43021 aacaacaaga agcaataaat ctgttgctga aatttcatcg ccttccacat attattgaaa
    43081 tcactaacga cataataaaa tatgtcatcg cacatgcaga ttatccgggg aatgaatatc
    43141 tctttggcaa agaaatagcg gagagagaac tactctggcc tgttgatcgt gtgcagaaat
    43201 cgcttaatgg cgagttacaa caaataaacg gcgctgatta ttttatattt ggacatatga
    43261 tgtttgataa cattcagacg ttcgcaaacc agatttatat tgataccgga tcgccgaaaa
    43321 gcgggcggct gtcattttat aaaataaagt agtctcatgc ttcttctgtg aagcatgagt
    43381 aacccggtgt tattgcaggc cattattcat ttttcgctac cagcaaagag agatcctgct
    43441 tcgccagcgc gcgactggca ctctccggca aaccgtcgtc tgtaataatc tgatcaaact
    43501 cgcttaatgg taacgccagc catgtcgcca cctgaccata tttcgtcgca tcacagacca
    43561 aaactcgctg gcggctggca ctggcaatcg cccgtttcac cgtgacttta tcttccgctg
    43621 gcgtagaaat cccccgcaca ctccatgacg atgcagaaat aaaagcctga tcaatcatca
    43681 ggctgcgcag catggtcgca gcggcttccc cgacacagga acggttttcc cgacacactg
    43741 caccgccagt gtgaataatt gtgcaattac tgttgtcgag caagtagtcc gcaataacga
    43801 aatcgtttgt gaccacagtc agtgactcca tgtgaatcag atgctgtgct atcgctagcg
    43861 tggtcgttcc cgcatccaga tagatacaac ttcccggctg aacaagactt gccgccagct
    43921 tgccaatagc cgctttttgc gtcattgcca gcgcagtttt tacctgatga gaaggttcat
    43981 gcgccacgcg tcccggagac tggacgcctc cggacaccag cacaacggct ccctgctgct
    44041 ccagtttttg taaatcccga cgaatggtca tatgtgacac attcattctg tccgttagtt
    44101 cagcaatact gacaatgcct ttttcagcta ccatctcaag gatgatttgg cgacgctcta
    44161 cgggtatcaa cttttgctcc ttcctttgtc ctgctgacat tctacgctat ttgcctgcga
    44221 aacgtgcgcg gcgcaactaa cgcttagttc acataaaata acacacaatg ttaatttttg
    44281 tgaatcagct caccatatcg ttatcttcca gcgcctatat tcacaatatc aaacaaaata
    44341 tcacttaaat taacaaggag agcagatgaa aacgggatct gagtttcatg tcggtatcgt
    44401 tggcttaggg tcaatgggaa tgggagcagc actgtcatgt gtccgcgcag gtctttctac
    44461 ctggggcgca gacctgaaca gcaatgcctg cgctacgttg aaagaggcag gtgcttgcgg
    44521 ggtttctgat aacgccgcga cgtttgccga aaaactggac gctctgctgg tgctggtggt
    44581 caatgcggcc caggttaaac aggtgctgtt tggtgaaaca ggcgttgcac aacatctgaa
    44641 acccggtacg gcagtaatgg tttcttccac tatcgctagt gctgatgcgc aagaaattgc
    44701 taccgctctg gctggattcg atctggaaat gctggatgcg ccagtttctg gtggtgcagt
    44761 aaaagccgct aacggtgaaa tgactgtcat ggcctccggt agcaatattg cctttgaacg
    44821 actggcaccc gtgctggaag ccgttgccgg aaaagtttat cgcataggtg cagaaccggg
    44881 actaggttcg accgtaaaaa ttattcacca gttgttagcg ggcgtacata ttgctgccgg
    44941 agccgaagcg atggcacttg cagcccgtgc ggggatcccg ctggatgtga tgtatgacgt
    45001 cgtgaccaat gccgccggaa attcctggat gttcgaaaac cggatgcgtc atgtggtgga
    45061 tggcgattac accccgcatt cagccgtcga tatttttgtt aaggatcttg gtctggttgc
    45121 cgatacagcc aaagccctgc acttcccgct gccattggcc tcaacagcat tgaatatgtt
    45181 caccagcgcc agtaacgcgg gttacgggaa agaagacgat agcgcagtta tcaagatttt
    45241 ctctggcatc actctaccgg gagcgaaatc atgatcaaga ttggcgttat cgccgatgat
    45301 tttaccggcg cgacggatat cgccagtttt ctggtggaaa acggtctacc aacggtacaa
    45361 attaacggtg ttccaacagg taaaatgccg gaagcaatcg acgcactggt gatcagcctg
    45421 aaaacgcgtt cctgtccggt tgttgaagcc acacagcaat cgctggcggc tctgagctgg
    45481 ttgcaacagc aaggttgcaa acagatctat ttcaaatact gctctacttt cgacagtacg
    45541 gcgaaaggta atatcggccc ggttaccgat gcattaatgg atgctctcga cacgccgttt
    45601 acggtcttct ctccggccct gccggtcaac ggacgtacgg tttatcaggg gtatttgttc
    45661 gtaatgaatc aactgctggc cgaatctggg atgcgccatc acccggtaaa tcccatgacc
    45721 gacagctatc ttccccgtct ggttgaagcg caatccacag ggcgctgcgg cgtcgtttcg
    45781 gcacatgttt tcgaacaagg tgtggatgcc gttcgtcaag agctggctcg cttacagcaa
    45841 gagggctacc gctacgcggt gcttgatgcg ctgaccgaac accatctgga aattcaggga
    45901 gaagccttgc gcgatacccc actggtaacg ggcggttctg gtctggcgat tggccttgcc
    45961 cggcagtggg cgcaagaaaa cggtaaccag gctcgcaaag cagggcatcc gctcgctggg
    46021 cgcggcgtag tgctctccgg ttcatgctct caaatgacca accgccaggt agcacattac
    46081 cgtcaaattg caccagcccg tgaagttgat gtggcacgct gcctctcaat tgaaactctg
    46141 gccgcttatg cacacgaact ggcagagtgg gttctgggcc aggaaagtgt acttgctcca
    46201 ctggtttttg ccaccgccag cactgacgca ttggcagcaa ttcaacagca atacggtgca
    46261 cataaagcca gtcaggcagt agaaacactg ttttctcaac tagcagcgcg gttagcagcg
    46321 gaaggcgtga cacgctttat tgtcgcaggc ggtgagacct ccggcgtagt cacacagagc
    46381 ctgggaataa aagggtttca tattggccca accatttctc ccggcgtgcc gtgggtaaac
    46441 gcactggata aacctgtctc actcgccctt aaatctggca acttcggtga tgaagccttt
    46501 ttttcacgag cccaaagaga gtttttatca tgagcgattt cgcaaaagta gagcagtctt
    46561 tgcgagagga gatgacgcgg attgccagtt cattctttca gcgcggctat gcaaccggtt
    46621 cggctggcaa tttgtcgctg cttttacctg acgggaattt actggcgaca ccgacaggtt
    46681 catgcctggg caatctcgat ccgcagcggc tttccaaagt cgccgcggat ggcgaatggt
    46741 taagtggtga caaaccctcg aaagaggtgc tctttcatct ggcgctgtat cgcaacaatc
    46801 cgcgctgtaa agcggtggtg catttgcaca gcacatggtc gacggcgctt tcctgcctgc
    46861 aagggctgga cagcagcaac gttattcgtc cgttcacacc atacgtggtg atgcggatgg
    46921 gaaatgtccc gctggtgcct tattaccgac cgggcgataa acgcatcgca caggatctgg
    46981 cggaactggc agcagacaat caggcttttt tactggcaaa tcatggccca gtggtttgcg
    47041 gtgaaagcct gcaagaagcc gccaacaata tggaagagct ggaggaaacg gcaaagctga
    47101 tttttattct cggtgaccgc ccgatccgtt atctgaccgc aggtgaaatt gcggaattaa
    47161 ggagttaatg caatgcctcg ttttgcagct aatttatcca tgatgttcac cgaagtgcct
    47221 tttattgaac gcttcgccgc agcgcgaaaa gccgggttcg atgctgtgga atttctgttt
    47281 ccctatgact actccaccct gcaaatccaa aagcaactgg agcaaaacca tctgacactg
    47341 gcgctgttca ataccgctcc cggagatatt aatgcggggg aatggggatt atccgccctt
    47401 cccggacgtg agcacgaagc acacgcagac atcgacctgg cactggaata tgcattggcg
    47461 ctcaattgtg aacaagtcca tgtgatggca ggcgtcgtgc ccgctggcga agatgctgaa
    47521 cggtacaggg cagtatttat cgataatctc cgctacgctg ccgaccgctt tgcgccacac
    47581 ggcaagcgaa tattagttga agcactcagc cccggcgtta agcctcatta tctcttctcc
    47641 agccagtatc aggcactggc tattgttgaa gaagttgcgc gagataacgt gtttattcaa
    47701 ctagatactt ttcatgcgca aaaagtagat ggcaacctga cgcatttaat ccgcgactac
    47761 gccgggaaat atgcgcacgt acaaattgcc ggactacctg atcgacatga accggacgat
    47821 ggagaaatca actatccgtg gctgttccgc ctgttcgatg aggtgggata tcagggctgg
    47881 atcggttgtg aatataaacc tcgtggcctc accgaagaag ggcttggctg gtttgacgcc
    47941 tggcgctaat tcgttaaatc cctaattaca acgtacccat acatcccccc atctacggat
    48001 ggggtaggtt aactataact ttcagacagg gtttcccatg tccacaatta cattgttatg
    48061 cattgcgtta actggcgtaa tcatgctgtt gctgctggtc atcaaggcaa aggtacaacc
    48121 attcgttgct ctgctcctcg tcagcctgtt agtcgcactt gcggcgggta taccggcggg
    48181 cgaagtgggt aaagtgatga tcgccgggat gggcggtgtg cttggttccg tcactattat
    48241 tattggtctg ggcgctatgc tggggcgtat gatcgaacac tctggtggtg cagagtcact
    48301 ggctaattat ttcagtcgca agttaggtga caaacgaact atcgctgcgc tgactctggc
    48361 agcgttcttc ctcggtattc ccgtcttctt tgatgtcggc tttattattc ttgcgccaat
    48421 catttacggt tttgccaagg ttgccaaaat atcgccactc aaatttggcc tgcctgtcgc
    48481 tggaatcatg ctaactgttc atgtggcggt accgccgcat ccaggccctg tcgccgcagc
    48541 ggggttactc cacgcagaca tcggctggct aaccatcatc ggtattgcga tttctattcc
    48601 cgtagggatt gttggctact ttgcagcgaa aataatcaat aagtgccaat atgcgatgtc
    48661 ggtggaagta ctggaacaga tgcaactggc tccggccagt gaggaaggcg cgacaaaatt
    48721 aagcgataaa ataaatccac cgggcgtcgc gctggtcacc tcgctaattg ttattcctat
    48781 cgcgattatc atggcgggta cggtttccgc aacactgatg ccgccttcgc atcccctgct
    48841 tggtacgcta cagctgatcg gctcaccaat ggtagctcta atgattgcgc tggtgctggc
    48901 attctggtta ttggctttac gtcgcggctg gagcttacaa cacaccagcg acattatggg
    48961 ctcagccctt cccaccgcgg cggtagtgat tttggttact ggtgctggag gggtatttgg
    49021 caaagtgctg gtggaatcgg gcgtcggcaa agcccttgcc aacatgctac aaatgattga
    49081 cctgcctctg ttaccagccg catttattat ttcactggcg ctgcgtgcat cgcaggggtc
    49141 agcaaccgta gcaatcctga caaccggcgg gttactctca gaagcggtga tgggattgaa
    49201 tccgattcag tgcgtattgg tgacgctggc agcctgcttt ggtgggcttg gcgcgtcaca
    49261 tattaatgac tcagggttct ggattgtgac caaatatctg gggttatcgg tagcagacgg
    49321 tctgaaaacc tggacagtgt taacgaccat tctcggtttt accggattct taattacctg
    49381 gtgcgtatgg gcggtaattt gaccttaata aaaaggtccg atgggcatcg gaccttttat
    49441 ttagcgctta ccttccgcta gcagcggcgg gatgctcggc accatcggcg cgtcatcaat
    49501 atctttctgt gtcatgcgga acgcttcggg ataatgttcg cggctggtgc ggcgtagcgg
    49561 ttcggtatcg cgccaggtat agaggcaatg ctggcactgg tagaccgtcc agacatcttt
    49621 taccggcgat ttcgccatca cttcaatctg ttcatcagca caacgtggac aaatcatctt
    49681 gttctcctta tttacgtgcg gccagcatag cggtcagttt ttcagcccag gctttggttt
    49741 ccggtaaatc caccaccggc tggctgtagt gaccacggtt gtccggggcg acaggcgtgg
    49801 tggcgtcgat aatcagcttg tcggtgatac cggccgggct tgagccgggg tcgagttcca
    49861 gcacggacat attcggcaac tgcaccaaat cccctgccgg gttcactttc gaagagagcg
    49921 cccacatcac ctgcggcagg ttgaacggat caacgtcttc atcgaccata atcaccatct
    49981 tcacgtagcc cagaccgtgt ggcgtggtca tcgcacgcag gcccaccgcg cgggcaaagc
    50041 caccgtagcg ttttttggtg gagataatcg ccagcaggcc gtgggtgtac atggcgttca
    50101 ccgcctgcac ttccgggaac tcggctttca gttgctgata cagcggcacg caggtggctg
    50161 gccccatcag gtagtcgatt tctgtccacg gcatgccgag gtacagcgat tcgaaaatcg
    50221 gcctggtgcg gtaagagact ttatcgatac gcaccacggt catgttacgc ccgccggagt
    50281 agtgcccggt aaactcaccg aacggccctt cgatttcgcg tttacgactt tcgatgaccc
    50341 cttcgaggat cacttctgaa ccccacggca catcaaaacc agtcagcggg gcggtggcga
    50401 tcgggtacgg gctttcacgc agcgcgcctg ccatttcgta ctcggactga tcatatttca
    50461 gcggcgtggc ccccatcagc gtgatgatcg gatcgttacc caaggtgatg gcaatcggca
    50521 gatcttcacc gcgttcttcc gctttatgca gatgcagggc gatatcgtgc atcggcaccg
    50581 gttgcaggcc gagcttacgt ttgcccttca cttccatacg atagataccg acgttctgct
    50641 tgccgaagtt atccgggtcg agcggatcgc gggaaaccac gcacgctttg tcgagataga
    50701 aaccgccatc gccatcgttt aaacgaaaca gcggcaggat atcgaacagg ttgatctcgt
    50761 cgccatcgac ggtgttctgc gcccaggctg gattggcgcg gcgctccggg gcaatcggga
    50821 agttatccca gcggcggata aactcatcaa tctgcttttt gaccggggtg tttggcggca
    50881 ggccgaggga aatcgcgtgg ttctgccagg aaccgatggt attcatcgcc acacgggcat
    50941 cggtaaagcc gcgaatattg tcaaaccaca gcgcgggcgc gccgtcgccg atacgcccgg
    51001 tggcgttagc tgctgctgcc agatccggtt ccgcgttcac ctcttcgctg attttcagta
    51061 actgtccgtg gtcatcaagc gcctgtaaaa agctgcgtaa atcatcaaat gccattattc
    51121 attctcctga gaaaaattcc ggacctgcgg caatccttgc cagcgcctgg cgtggggatg
    51181 ttcgaggcca aattgatcca gcacgcgggc taccacgtgg tggacaatgt catctaccgt
    51241 ttcgggatgg ttataaaagg caggcatcgg cggcaccatc gccacgccca tgcgtgaaag
    51301 tgcgagcata ttttcgagat ggatggtgct aagcggcatt tcacgcggca ccagcactag
    51361 tttgcggcct tctttgagca cgacgtccgc cgcgcgccct accaggccat cggcgtaacc
    51421 gacacggata ccggcgagcg ttttcatact gcacggaata acgatcatgc cgtcggtacg
    51481 aaaggaacct gaggagatgg tcgccgcctg atccgccggg ttatgactga agtctgcgag
    51541 ggcagcaaca tcgcgagcgc tgtaaggcgt ttccagttca atggtggttt tcgcccactt
    51601 cgacatcacc agatgagtct cgacattcgg catctcccgc agcgcttgca gtaatgccac
    51661 cccaagaggc gcaccggtag cccctgtcat cccgacgatc agtctcattg tttattctct
    51721 taattgttcg tatacgaacg ttattattaa aatacgcctc tgttttcatc gcggcaagca
    51781 ctgaaaagta acaacatctt cttcgtcact gaaaaaccgc tatgatagcg gcagatagtt
    51841 tgcccggagt ttacatggcg ttacgaaata aagcgttcca tcagttacga cagctttttc
    51901 agcagcacac ggctcgctgg cagcacgagt tacctgacct caccaaacca cagtacgcgg
    51961 tgatgcgcgc cattgctgat aagcctggta tcgaacaggt ggcactgata gaagcagcag
    52021 tcagcaccaa agcaacgctg gcagaaatgt tggcaagaat ggaaaatcgt ggcttagtca
    52081 gacgtgaaca tgacgccgct gacaagcggc gtcgctttgt ctggctgact gccgaaggag
    52141 aaaaggtact tgctgcggcg atccccattg gtgacagtgt ggatgaggaa tttttggggc
    52201 gtttgagtgc agaagagaag gagctgttta tgcagttggt gcgcaagatg atgagcaaat
    52261 aggatgctga ttgccgggta ggacgctgac gagtcttatc caggcgacaa aacacaccga
    52321 cttcccaaac aaaagaaaaa ggccagcctc gcttgagact ggcctttctg acagatgctt
    52381 acttactcgc ggaacagcgc ttcgatattc agcccctgcg tttgcaggat ttcgcgcaaa
    52441 cggcgcaggc cttcaacctg aatctggcga acacgttcac gggtgaggcc aatttcacga
    52501 cctacatctt ccagtgttgc cgcttcgtac cccagcaaac cgaatcgacg tgccagtact
    52561 tcacgctgtt tggcgttcag ctcgaacagc catttgacga tgctctgctt catatcgtca
    52621 tcttgcgtgg tatcttccgg accgttctct ttttcatcgg ccaggatgtc cagcaacgct
    52681 ttttcggaat caccacccag cggggtgtct accgaggtaa tgcgctcgtt aagacgaagc
    52741 atacggctga cgtcatcaac tggcttatcc agttgctctg cgatctcttc cgcacttggt
    52801 tcgtggtcca gtttatggga caactcgcgt gcggttcgca ggtaaacgtt cagctccttt
    52861 acgatgtgaa tcggcaaacg aatagtacgg gtttggttca taatcgcccg ttcgatcgtc
    52921 tggcgaatcc accaggttgc gtatgttgag aagcggaaac cacgttccgg gtcaaacttc
    52981 tctaccgcgc ggatcagccc caggttgccc tcttcgatca ggtccagcaa cgccagacca
    53041 cgattgccat aacggcgggc aatttttacc accagacgca agttactctc gatcatccgg
    53101 cggcgggagg caacatctcc acgcagtgcg cgacgcgcaa aataaacttc ttcttcggcc
    53161 gttaacagtg gtgaataacc aatctcacca aggtaaagct gagtcgcgtc caacacacgc
    53221 tgtgtggctc cctgcgataa cagttcctct tcggccaaat cgttatcact gggttcctct
    53281 tctactaagg ccttttcgtc aaaaacctca actccgttct catcaaattc cgcatcttca
    53341 tttaaatcat gaactttcag cgtattctga ctcataaggt ggctcctacc cgtgatccct
    53401 tgacggaaca ttcaagcaaa agcctggttc cgccgattta tcgctgcggc aaataacgca
    53461 gcgggtttac ggatttcccc ttgtaacgaa tttcaaaatg caagcgtgtt gaactggttc
    53521 cggtgctacc catggttgct attttttgcc ccgccttcac ttcttgttgt tcccggacca
    53581 gcattgtgtc gttatgggcg taggcactca ggtaatcatc attatgtttg atgataatca
    53641 gattaccgta gccgcgcagc gcgttaccgg cataaacaac gcggccatct gcggtcgcga
    53701 taattgcctg tcctttgctg cctgcgatat caatcccctt gttgcccccc tcagaagcgc
    53761 caaaggtttc gatcactttg ccctcagtcg gccagcgcca ggtggagata ggcgtactgg
    53821 ttgatgtact gctgacagtc ggctcggttg tgcttgctgt tggcaccgtt acaggcgctg
    53881 tgaccgtggt cgcagttggc ttgttgttcg gcaacatttt gttagcactc tgttcacccg
    53941 aagactcaga atacgtaatt gtcggttgcg acgcaacagc aacggtggaa ttttgtgcag
    54001 gcttgatcac aactccttgc tctgctgcgt cggcctgggt aatggcattt ccgccagtga
    54061 ttggcgtacc ggaagcatta cccacctgca aggtctgacc aacgttcagc gcgtatggtg
    54121 cctgaatatt gttgcgctga gcaaggtcac ggaaatcgtt gccagtaatc caggcgatat
    54181 agaaaagtgt gtcgcctttt ttcacggtat aggtactgcc gctataactg cctttcggaa
    54241 tgttcccata ctgacggtta tagacgatgc gtccgttttc catctgtacc ggctgctgag
    54301 ctactggctg caccggctgg atttgcggtt gttgagtggc ctgaatttgt ggctgctgta
    54361 ccggctgaat ttgcggttgc tgagctgtag acgtcgttcc cattttcggc ggcggcgtaa
    54421 tcaacatacc agaattggta tttgcaggcg cattgccatt aacggagctg accggtgccg
    54481 gtggatttga agtgtcagaa cagcctgcca gccatagcga aaccagtgac aaagccgcaa
    54541 tgcggcgaac ggtgaatttt gggcttcccg cgctcattta tcccccagga aaaattggtt
    54601 aataaccagt gacataatta ccgtgcaagg caccatactg aacactggaa aagatgttca
    54661 cgatacgctg acctgcggca aaataaccag gaaaaatcca ggtatttcct cacgttttaa
    54721 gccagctcac ccttcactaa agggacaaag cgcacggcct ccacggtatc gataataaat
    54781 tcgcctcccc gacgacgcac ccgtttcaaa tactggtgct cctcccctac gggtaagacg
    54841 agaatcccgc cttcgtccag ctgcgtcatt agcgcagttg gaatttccgg cggtgccgcc
    54901 gtaacaatga tagcgtcaaa cggcgcacgt gcctgccaac cttgccatcc atcgccatga
    54961 cgggttgaaa cattatgtaa atcaagattt ttcaggcggc gacgcgcctg ccactgcaag
    55021 cctttaatcc gttcgaccga gcaaacatgc tggacaagat gcgccaggat tgccgtttga
    55081 tatcccgaac cggtgccaat ttccagcacc cgcgactgcg gcgtcagttc gagtaattcg
    55141 gtcattcgcg ccaccatata cggctgcgaa attgtctgcc cctgacctat cggcaaggcg
    55201 atattgtccc aggctttttg ttcaaacgct tcatcaacga atttttcacg cggcacggcg
    55261 gcaagtgcat tcagcacctg ctcatcctga ataccttgcg cacgtaattg atccagaagt
    55321 gcttgtacgc gtctgcttac cattgcgtgc caactcccac gctgtttaac cagtctgaaa
    55381 ccacatcttg cgcgctatgc gcagttaaat ccacatgcag cggcgtgatg gagacatagc
    55441 cctcatctac cgcagcaaaa tcggtccccg gaccggcatc acatttaccg cccggcgggc
    55501 caatccaata cagcgtattg ccgcgcggat cttgctgcgg gatcacctga tctgccggat
    55561 gtcgtgtacc gcagcgcgtc acgcgaatac ctttgatttg atccaagggt aaatccggaa
    55621 cgttaatatt aagaatacgt ccggtgcgca gcggctcttt acacagtgcg cgcaaaattg
    55681 aacaggttac cgccgcggca gtgtcgtaat gtttatgccc gtcaagcgag acggcaagcg
    55741 ccggaaaacc taaatgacgg ccttccatcg cggcggctac cgtaccggaa taaataacat
    55801 catcccccag attcggcccg gcgttaattc cggacacaac aatgtccggg cgcggacgca
    55861 tcagagcatt cacgccaaga tagacgcaat cggtcggggt tcccatttgc acagcaatat
    55921 caccattttc aaaggtaaac gtgcgcaggg aggattccag tgttagagaa tttgaagcgc
    55981 cgctgcggtt acgatcgggg gcgaccacct gaacgtcagc aaactcacgc aaggctttcg
    56041 ccagcgtttg tataccgggt gcatgtaccc cgtcatcatt actcagcaat atgcgcataa
    56101 tcacctgttg tgttgataag ttccctgaca acgctggttg caaaactacc cgccggaagc
    56161 cagaaacgga tttctacggt gacgtcatcc caccagttcc agcttaattg ttgcggatac
    56221 agcagcatcg ctctgcgcgc ggcttcaact ttttcgcgca ccagtaaggc ttgtaattca
    56281 gtttctgcgg cgacagctgc ttgttcgaat gccagcgctt cacgctgagt tccccattcg
    56341 ccactgcccg gcaatgcggc ggttatcatt agctctttat cgttgacgcg acgctgtaat
    56401 tccgccagtt cttcggtggt tgcgacaaac cagctaccac gtccggctaa ttgtagcgca
    56461 tcgccgtcaa caacttgatt aacgtctgct tttttgaggc gctcagcaac aatctgatta
    56521 aacaacgcac tgcgggctgc cgacaaccaa aaactccgtt tattgcgatc gcgcaccgga
    56581 gtattggttt gcgcccagcg cagcgcgccc tgcaagttgc taccgccaat cccaaaacgt
    56641 tgggcaccaa aatagttagg cacgcctttt acgcaaatat cgatcagacg ttgttcaacg
    56701 tcatcgcgat tgctcacttc gcgcagaacc agggtaaagg cgttaccttt cagcgcgcct
    56761 aaacgcagct tgcgcttgtg ccgcgcatac tccagcacct ggcagccttc cagttgaaag
    56821 gcgctcagat cgggcatttc cttgcccggc acgcgagcac ataaccactg ttccgttaca
    56881 gcatgtttgt ctttttgccc agcgaagctg acttcacggg catgaatttt aaggaatttc
    56941 gccagtgcat ccgccacaaa acgggtattg cagccgtttt tgaggattct aaccagaata
    57001 tgctcacctt caccatcagg ctcaaagccc aaatcttcca ccaccacaaa gtcttccgga
    57061 ttggctttca gcagcccagt gccttgcggt ttaccgtgga ggtaagtgag attatcaaac
    57121 tcaatcattt tgttgcctta atgagtagcg ccaccgcttc acaggcaatc ccttccccac
    57181 gtccggtaaa tccaagtttt tccgtagtag tggctttcac gttaacatca tccatatggc
    57241 agccgagatc ttcggcaata aacacgcgca tttgtggaat gtgcggcaac atcttcggtg
    57301 cctgagcgat gatagtgaca tcgacgttgc ccagggtata acccttcgcc tgaatacgac
    57361 gccaggcttc gcgtagcagc tcgcggctgt cggcaccttt aaatgccgga tcggtatccg
    57421 ggaacagttt gccgatatcc cccagcgccg ccgcgccaag caatgcatcg gtcaacgcat
    57481 ggagcgccac gtcgccatca gaatgcgcca gcaatccttt ttcgtaagga atgcgtacgc
    57541 caccaatgat aagtgggcct tcaccgccaa aggcgtgtac gtcaaaaccg tgtccaattc
    57601 gcattatgta ttctcctgat ggatggttcg ggtgaggtaa aactcggcca gtgccaaatc
    57661 ttccggtcgc gtgactttaa tgttatccgc gcggccttcg accaactgcg gatggaatcc
    57721 gcaatattcc agcgccgagg cttcgtcggt aatggtagcg ccttcattta gagcgcgcgt
    57781 caggcagtca tgtaacagct cgcgagggaa aaattgcggc gtcagcgcgt gccataagcc
    57841 gttgcgatca acggtatgag caatggcatt tttgcccggt tcggcacgtt tcatcgtatc
    57901 gcgcactggt gcggcgagga tcccccccgt gcggctggtt tcgctcaacg ccaacaatcg
    57961 cgcgaggtca tcctgatgca gacaaggacg agcggcgtca tgcaccaata cccactgcgc
    58021 gtcgccagcg gctttcagac ctgccagcac cgaatcggca cgctcatcac cgccatctac
    58081 aacggtgatt tgcggatgat tcgccagagg aagttgtgca aaacggctat cgccaggact
    58141 tatggcaatg acgacacgtt tcacccgggg atgcgccagc agcgcatgca ccgagtgttc
    58201 aagaatggtt tgattaccga ttgagagata ttgcttagga cattccgttt gcattcgacg
    58261 gccaaatccg gccgccggaa ccacggcgca aacatccaaa tgagtggttg ccatgttaat
    58321 tcccgggctg atttatcgat tgttttgccc cgcagactgt gcgcgcttcg acgcgtcagg
    58381 caccagacga taaaaagttt cgcccggcct ggtcatgctg agttcattac gcgcacgctc
    58441 ttcgagcgcc tcctggccgc cattgagatc gtcaatttcg gcaaaaagtt gatcgtttcg
    58501 cgctttaagt ttcgcgtttg tagcttgctg tgccgccaca tcatcattga cgcgggtata
    58561 gtcatgtata ccgttcttac cgaaccacag cgaatactgt agccagacca gaatagccag
    58621 caacagcagc gttagtttac ccatcctgcc ccctgaaaaa cggcatcatc atcccatgca
    58681 tccgaagacg actctacatc ctctgttggg gataccgcga caacgcgggc aaatgtacca
    58741 catttgtcca ttgttacgta tacccagggc gtgcagaaca taatctcatt attagttacg
    58801 gtttgaatta tgaacagagg agacaagaaa gtacaaatta gcccagtagc cacataaaca
    58861 gtgcgccaaa cataatgcct actgtcacca gggtgaaaac aatactgtag cgtagctttc
    58921 cgtccatcaa tgaatgcagc gcaatcccca ccactaccgc gacaggcatc agtgccagaa
    58981 agaaaggcca ggtgtagata aagaaaaaca gcgtgttaga gccataaatc aacatcggca
    59041 tcgccagcgc aaataaccag gagataaaac cgaccacagc accaggcagt gaccatgtgg
    59101 tttcttcatc ctcagtaagg ctgtcgttat ttgttagtgt aatgttatgg ctattacgca
    59161 tatttgatcc tgttactttg acgaaccggg catggaaacc cggtggtgtc tcaggatctg
    59221 ataatatcgt tctgtctcaa cagatctaat aattgctgta ccaaatttgt tactaattgt
    59281 tcaccattga gatgaatttc tgccgattca ggcgcttcgt aaacggaatc tattcccgta
    59341 aagttgcgca gttcaccggc acgcgctttc ttatataagc cttttggatc gcgggcttcg
    59401 caaatcgcca gcggcgtatc gacaaacact tcgataaagc gcccttctcc tacgcgttca
    59461 cgaaccatct ggcgttcggc gcggtgtggc gagatgaatg cggtcagcac caccagtccg
    59521 gcttcaacca tcaaattcgc cacttcaccg acgcgacgga tattctcttt acgatcggca
    59581 tcgctaaaac cgagatcgct gcataatccg tggcgaacat tgtcgccatc cagcagatac
    59641 gtactgacgc cgagtttatg taacgcctcc tccagcgccc cggcgaccgt tgatttaccg
    59701 gacccggaga ggccggtaaa ccacagcact acaccacgat gaccgtggtg tagctcgcgt
    59761 tgttgcacag tgaccggatg gctatgccag acgacgtttt cgtcatgcag cgccattatt
    59821 tatcccccag caaatcgcgt gcgccccagt gcggaaagtg gcgacgaacc agggcattca
    59881 attccagttc gaatgcactg aattcagatg gcgcagcagt tgcctggcta actggctcgt
    59941 gcaccatacc ggcacccacg gtcacattgc tcaggcgatc gataaaaatc agcccaccgg
    60001 taaccggatt ttgctgataa cgatctaaca ccagtggctc gtcaaaagtg agatccacca
    60061 ggccgatgcc gttcagcggc aggttttcaa cttcgcgttg ggtaaggtta ttaatatcaa
    60121 cctgataacg aatgccatca acacgagcac gtgtcttctt accggcaatt ttgatgtcgt
    60181 aactctggcc tggggaaagc ggctgttccg ccatccatac cacatccacc gacgcgctct
    60241 gcacagccgg taacgcttcg tctgccgcca gcagcagatc gccacggctg atgtcgatct
    60301 catccgtcag cactagggtg atcgcttctc cggcaaaggc ttcttcgcga tcgccatcaa
    60361 aagtcacgat ccgcgcgacg tttgattcca caccagaggg cagcactttg acacgttgcc
    60421 cgacttccac tcgaccggat gccagcgttc cggcgtagcc acgaaaatcg agattcgggc
    60481 gattaacgta ctgcaccggg aagcgcattg gctgggcatc caccactcgc tggatctcca
    60541 cggtttccag cacttcgagc agtgtcggac cgctgtacca cggcatactt tcactttgcg
    60601 aagccacgtt gtcaccttcc agtgcagaga gcggcacaaa gcggatatcc agattacccg
    60661 gcagctgccc ggcaaaggtc agataatctt cgcgaatacg ggtgaacgtc tcttcactgt
    60721 aatccaccag atccattttg ttgatcgcca cgaccagatg tttgatcccc aacagtgtgg
    60781 agataaaact gtgacgacgg gtttgatcga gcacgccttt acgggcatcg atcagtaaga
    60841 tcgccagttc acatgtcgat gcgccagtcg ccatattgcg agtgtactgc tcgtgccctg
    60901 gggtatcggc gataataaat ttacgcttct cggtagagaa ataacggtaa gccacgtcaa
    60961 tggtgatgcc ctgttcgcgc tcagcttgca ggccgtccac cagcagtgcc agatccagtt
    61021 tttcgccctg ggtgccgtga cgtttactgt cgttatgcag cgatgagagc tgatcttcgt
    61081 agatttggcg ggtatcgtgc agcaggcgac caatcagggt acttttgccg tcatcgacgc
    61141 taccacaggt cagaaaacgc agcaggcttt tatgttgttg tgcaatcatc caggcttcga
    61201 cgccgccttc attggcgatt tgttgtgcaa gtgcggtgtt catcttaaaa atacccctga
    61261 cgttttttca actccatgga tcccgcctgg tcgcggtcaa tcacgcgacc ctgacgttca
    61321 ctggtggtgg aaaccagcat ctcttcgatg atttccggca gtgtttgtgc atttgactcc
    61381 accgcaccgg tcagcggcca gcagcccagc gtacggaaac gcaccatccg ttttttaatc
    61441 acttctcccg gttgcaggtc gatacggttg tcatcaatca tcatcaacat accgtcgcgt
    61501 tccagaaccg gtcgttccgc agcgagatac agcggcacaa tgtcgatatt ttccagccag
    61561 atgtattgcc agatatcctg ctcggtccag ttagagagcg ggaagacgcg aatgctttcg
    61621 cctttgttaa tttgcccgtt gtagttgtgc cacagctccg ggcgctgatt tttcggatcc
    61681 cagcgatgga agcggtcacg gaaagagtag attcgctctt tagcacggga tttctcttcg
    61741 tcgcggcgtg caccaccgaa ggcggcatca aaaccgtatt tattcagcgc ctgtttcagg
    61801 ccttcagttt tcataatatc ggtatgtttc gcgctgccat gaacgaatgg attaatcccc
    61861 atcgccacgc cttccgggtt tttatgcacc agcagctcgc agccgtaggc tttagccgta
    61921 cgatcgcgga actcatacat ctcgcggaat ttccagccgg tatcgacatg cagcaacggg
    61981 aaaggcagcg tacctggata aaacgccttg cgcgccagat gcagcatgac gctggaatct
    62041 ttaccgatag agtagagcat caccggattt gagaattctg ccgccacctc gcgaataatg
    62101 tggatgcttt ccgcctccag ttgccgcagg tgagtaagtc gtttttgatc cataaccgtt
    62161 cctttgcaat accgctattt tcttgccatc agatgtttcg actataggga gcgtaagaga
    62221 acgaatgaaa ttaccaatta gaatgagtag ttccttaacg gaataacgat ttggcaaagc
    62281 taatatcaaa aagtgcttaa ggcaccggat ttcgggcgtt taggaagatt tgaaattgtt
    62341 ttagcgcatc ggcagtttca tactatggcg gtaaaaaaat ttgcatggta tttaaggact
    62401 cactatgttt tccgcattgc gccaccgtac cgctgccctg gcgctcggcg tatgctttat
    62461 tctccccgta cacgcctcgt cagctaaacc tggcgatttt gctaatactc aggcacgaca
    62521 tattgctact ttctttccgg gacgcatgac cggaactcct gcagaaatgt tatctgccga
    62581 ttatattcgc caacagtttc agcaaatggg ttatcgcagt gatattcgga catttaatag
    62641 tcggtatatt tataccgccc gcgataatcg caagagctgg cataacgtga cgggaagtac
    62701 ggtgattgcc gctcatgaag gcaaagcgcc gcagcagatc atcattatgg cgcatctgga
    62761 tacttacgcc ccgctgagcg atgctgacgc cgatgccaat ctcggcggac tgacgttaca
    62821 aggaatggat gataacgctg caggtttagg tgtcatgctg gaactggcag aacgcctgaa
    62881 aaatacgcct accgagtatg gtattcgatt tgtggcgacc agcggcgaag aggaagggaa
    62941 attaggcgct gagaatttac tcaagcggat gagtgacacc gaaaagaaaa atacgctgct
    63001 ggtgattaat ctcgataact taattgttgg cgataaattg tatttcaaca gcggtgtaaa
    63061 aacccctgaa gcagtaagga aattaacgcg cgacagggcg ctggcaattg cgcgtagtca
    63121 tggaattgcc gcaacgacca atccgggttt gaataaaaat tatccgaagg gtactggctg
    63181 ttgtaatgat gccgaagttt tcgacaaagc cggtattgcc gtactttcag tagaagcaac
    63241 aaattggaat cttgggaata aggatggtta tcagcaacgc gcaaaaacag ctgcattccc
    63301 tgcgggaaat agctggcatg acgtaagact ggataatcaa caacatattg ataaggcact
    63361 tcctggaaga atagaacgtc gctgccgtga tgttatgcgg ataatgctac cgctggtgaa
    63421 ggagctggcg aaggcgtctt gatgggtttg aaaatgagag ctgggagttc taccgcaggg
    63481 gcggggaact ccaagtgatg tccatcatcg catccagtgc gtccggttta tccccgctga
    63541 cgcggggaac acgtcaatag gcggcgtccc gtagccgtcc ccttcggttt atccccgctg
    63601 gcgcggggaa cacgttgagg tcgataagta cgaacggttt ccctgcggtt tatctccgct
    63661 ggcgcgggga acacgatcgc ctgctccagc gtcactccct gcccctcgat ttatccccgc
    63721 tggcgcgggg aacacttctg atacgtactg aggccggttg tgatacgcga tttatccccg
    63781 ctggcgcggg gaacactaac ccccaatgaa gttaataaag tctatggccg atttatcccc
    63841 gctggcgcgg ggaacaccag cgtggcgcga taaagcaatg tgtctggctc gatttatccc
    63901 cgctggcgcg gggaacacca gaggcaaccg acgcggattc agtaggaaag cgatttatcc
    63961 ccgctggcgc ggggaacacc gatagacact ttgcggtcat tgtctattcg gcgatttatc
    64021 cccgctggcg cggggaacac actaagcata cataactgtt tttaaacaaa tttattccgc
    64081 atcaacaatc taccaactaa attaaaacat ttccttattt ttaaagaaca gataacttat
    64141 tgattatcaa caggaagaaa agaaaccaaa cgcaccccat ccaaatccac cggaatacgt
    64201 ctattttcac cccaggtctg aaattcaaaa cccgactcgg tattggtcgc ccaggccatt
    64261 accacatttc cgcaacctgc cagttgagag atttgctgcc agatcatctc ccgaatacgt
    64321 ttggacgtat ctccgacata aacaccggca cgcacttcca ggagccagat cgcgatccgt
    64381 ccacgtaagc gcggagggac attttctgta acaacgacga ccatactcat ccgccgcgtc
    64441 cccggtgacc gctatcgccc agcgtttcag gttcagggat ggcaggcggt aacatatccg
    64501 gcgcgggttg tggtggttca atttcacctg cggcaagcac ttcctcgatt aacggaatta
    64561 atttgcccgt taacttactg ctacggaaaa tatcacgaca ggccaacctg acttctttat
    64621 ctggttctgc gggttgcctc gctgctattt caaatgcctt tggcacaacc gaatcaaatt
    64681 taatgatatc ggctatgtca taaacaaatg aaagcggttt gccactatgg ataaatccaa
    64741 tagcgggcgc atatcccgcg gctaatactg ccgcttcaga aataccgtac agacatgatg
    64801 tggcagcact gatgcagcga ttcacaacat cgcctttttc ccagtcttta ggatcgtatt
    64861 tgcgaccatt ccatttcaca ccatattgtt tcgccagtaa tgcatacgtc tggcgaacgc
    64921 gggatccctc aattccacgt agctgctcca ctgaacggcg agctggcggt ggctcacgaa
    64981 aacgtaattc atacattttg cgcaccacct tcagacgtag atcttccgtt aaagccagct
    65041 ttgcctggta gagtaactta tcagcacgcg ccccaccggg ttgtccggaa gagtagacgc
    65101 gaacacccgc ttcaccgacc cagaccagta gcgtccccac cgtggcggcc agatgcaccg
    65161 ccgcgtggga aactctcgtt cccggttcga gcataatgca ggcgaccgat cccaccggaa
    65221 tgtgcgtgcg gatcccggtt ttgtcgatca gcacgaaagc gccgtccagt acgtcgattt
    65281 gaccgtactg gaggaagatc atagaggtgc gatcttttaa cgggatcgga ctcagtggta
    65341 caaacgtcac gcctctgctc cgggtttgat cagcatcaga ccacagccga acgcgcggct
    65401 tttgccatac ccctggctca gacgttgcag aaataaccca ggatcggtga ccgtaagcat
    65461 ccccgtataa tccacgctac tgaactggat cagttgccgg gagttttccc gccgcagttg
    65521 ctgttgtcgg taggcatcga ccgaggtatc cagtagtgta aaaccgcttc tttccccctg
    65581 cgctgccagc cagtccagcg ccgcctgttg ttgatgcaac cagacatcac ttccttccac
    65641 ctgccccctc acctgccgtt tcgcctccat cagcaagtcg tggcgtttgc ccgctttaca
    65701 aattgttgga ttcgcccgca ggttgaaaca aagggattgt ccggtacgca actctggcgc
    65761 aaatggtcgg cattcgatgg tgaaaatatc actttccgcc gggcgttcct gcgacaggac
    65821 aaaaaagcga aacgccccct ggagttcttc ccgacgataa agaaattgcc tttctttgcc
    65881 gccaggaaaa agatcccaca gccactgatg cattacatat tcaccgcgac ccaccaaatg
    65941 cagcaactgc gcaggcaaaa gctggccggt atgtaaggtt attcttgaga ggtacatggt
    66001 tcctccttgc tgagccacgg cccctgattg atggtgcgtt ccccaaacag ccactgctga
    66061 cgatttaaag gaacatcccg gcgacgtaat attttgctcg cgaccaggcc gtcgtgttcc
    66121 ccttcccacc agcattcatc ctgaagtttc gggagtgaga ctttcagttc gcggaaacta
    66181 tcctgatact gttggtatgc gttacgtaag acatcagacg cgttgccttc gagcagtaac
    66241 ggcgcaagtg gtaacgccag cggatgactt tttcgcccca gataaagcgg aaaaaccgga
    66301 tgacgtaaac cgtcctgcaa ctgttcaagc ctgtaagacg catcgggggt tgttgccacc
    66361 gccaccatcc accaggcatc ggtgtagtag tcgcgccggg agataatcgc gctcagaaga
    66421 tcaggggcgc tcaactcttc gcgacggctg aaataacgcg ctttacgtac ctcttttggc
    66481 atctggaccg tgtgataatc ccgtgcccag cgcgggttac ggctggcgca aaccaccagt
    66541 gaatagtggc ggttaaacgc gtttaatcgt tcggtatcat cacgccgaat ccctaccccg
    66601 gcagccagca gccccagcaa tgctgagcgc gaaggcagtt catgggtatg acgcacttcg
    66661 ccgggggcat cgacgcccca ggatgccatt ggcccatgaa gctgaaaaat caaatattgg
    66721 ctcattagcc gccccttacg cgcagataaa gtccagcacg tccttcatgc ttccctgttt
    66781 gttcatcacg tcaaagctta cgcattcggt cttctgttca tagaccgtat tcatattttc
    66841 gcgaagcgtt gtaatacgct gcaccgccac atctaactgc cgggtgccat taatgggttc
    66901 atagaaagcc gccgccagag agcgtggttg ttcagtgcct ttttctgcca gcgcccagga
    66961 ggcgtaggca cggctggcaa agctgttctg tttgccggtt ggggagactt taagtgcggc
    67021 ttccgtaaag gcgcgcaagg tctgattagc taacgcttcg tcaccgccga ggttttcgac
    67081 cagcagatct ttatcgatgc agatataggt gtagaacagc gcagaaccga atccggtttc
    67141 accaagatgc ccggcaccgg catcttcaga agcctggcgc aaatcatcaa cggcggtgaa
    67201 aaaatcatct tcgacaatcg tttcactgac accaaatgca tgcgcgacct ggcaggcggc
    67261 ttcaacatta aattcgggtt tattcgccag catacgacca aacatagcga tatctaccgc
    67321 catgcgatct ttacgtaaca aagcgagatc ttcctctttt ggcgcgcgct tttcttcggc
    67381 cagttgatgg gccagcgctt ttacggcgtc aaattctgcc gggctgatat ggactagctg
    67441 ttcagtttcg gcgttagtga gcggatcttt tggttttttg tcgtttttag ctttcccaag
    67501 ataatccgca atttttgccg cccattcgat ggcttttttc tcttcgatgc ctttctcaat
    67561 caggatagtt gccgcctcac gcgcaatacg cccactgcga ataccaatat ggcccgccag
    67621 tgcctgttca aaaagtgcag aagtgcgcca cgcacgtttc agactttgtg aggaaacgcg
    67681 cagacgcgtt gctccaccca gtaccacagt ttttggcgca ccggtgtcat cacggttaag
    67741 gttggcagca gggtaagcgg ttaacaaatg aagctgaata aatgtcgtca tgagatagtc
    67801 ctttattaat tttgttcgtt atcggcgtcg ccagcctggt aatattccag cgcccagcgg
    67861 atacggataa attctgttgg ccgctgctgg cggcggtgat gattgagcag gtcgtcgctc
    67921 tcctggcacc agcggaaaat atcttctgcc aaagagataa gattgacgga accatttaat
    67981 aatttgaccg cgcgacgtaa ctgacgcagt aaatcatcag gcgtttttac tgccgacagg
    68041 cgagtaaaac gcccctccga cattaccgcc gccagctgcg cggcaaaagg ctgccgttca
    68101 tcaatagctt taacattggc gctaactgcg gcgaccagcg ccagtgcggt aaaacgccac
    68161 tcttgtgctt caattttcca caaagtgtgg gtctgcatca gcagagaacg aaacccttct
    68221 gacagacaaa catcattaac cgttgtgcta cgccgcagac tggcacgatt gccgcgtttt
    68281 tcctgcaact cttcgtgcca tttacgcagc gtggctttgt gctcctcttt tacaatactc
    68341 attcagcagc ctcctgcttt ttctccctgg cggctttagc attttgcttc tccgccgatg
    68401 ttgtaaaata tttcttgcgc gcggtcatga cgcgtttcaa atcaacgggc tcatatggat
    68461 tggtgaagac acgctcgtca aaatcctgac gcgcgaataa ccaaatttcc ttttgccatt
    68521 tgctgagtaa ttcatccgca tcctgacctt cttcaatgtg gcgcactaac ctcaggaagc
    68581 gatgctgagt tttgttccag aagtcgatat ccacaaaact gaaatcaccc cgtgcacctt
    68641 ttggatcgga gaaccacgct tctttcaatg cactccgtaa cagactcaga atccgtgaag
    68701 ccgtttgcgc agccagccgc agcttcggta tctggccttc ttttttatcg agcagcagcg
    68761 gaaaatggtg ttcgtaccaa cagcgcgctt tcatgttgtc aaaatcataa ccaaatcccc
    68821 acaggcccac ttttgcctgc ttgagactgc tggcattaaa gagtttcacc accagcgcgg
    68881 gaagttccgt attgttttct gatttacccg tttcgataag gcctaaccag tcgcgccaga
    68941 ttaaaccgcc tggttgtggt ttgaccgagt aaaactcgcc gccctcttta aggggtacac
    69001 ggtaaggcgt taagggatgc tgccacatgg cataattcgc gccgtaattt ttggtcgtca
    69061 tcaggctcag gagcgcgtcg ttctgctcgc cgcaaatatc gcagttgccg actgtcgtgg
    69121 tattaaaatc aatacgaata cgccgcggca ttccccagta cgcctggagt ttattaacct
    69181 gatcatcggt taccaccgca ccggccagtt cgctggtacg cgtcgggcca agccagggga
    69241 aaaccagatc gtcaaatttt ttgggtagcg gtaagtcggc ttcgtcctgc ggcatcacat
    69301 tgagccacag tttgcgccac aagggcgttt gttgattgcc ctgatattcc tgtaattcaa
    69361 tcagagtggt catcggccca ccgccgcgta aaccggtgcg gtagccttta ccacctgacg
    69421 gcgcatttaa ctgtagggag aacagagcta acgcagaaca atgtgggcac aggtattccg
    69481 ttacaccacg cttgataaag tggtctttat taaacttcgt tgtttgagcg ccgggaatct
    69541 caggcagtag cgaagcgacc tgaactttat ctcctgtgag cgcctcgaaa tcctgcataa
    69601 atgaagggga atctggccca aactggaaag cgtgttctaa ggacagcaat gcttcccgta
    69661 gcttttcaga ttccagtccg tcttcccaga tatcatccca acgacgatga tcttttggcg
    69721 caaagctggt ttgtagtagc cccagcaaaa actgccatgc cgctccctgg agatctgccc
    69781 gtggcgcagc aatatcgaca acattttcat ccgccagatc gacaggcgcc agtttgcctg
    69841 tcgttccgtc tttataacga acgggcaacc acggggttgt cagaagtgaa aacgagttca
    69901 tacgcatcct ctcgtaaaaa agaccatccc aggtcggttg tccatcattc catccttttc
    69961 ggtgtatcaa ctattcagag agccctgtcg caggcatctc aaccaacctt gccagtcaat
    70021 ccttccatag ccgaataccc gcaactttcg tcatcggtaa ctaaaatcac gtttgccatc
    70081 tccggatctt tccgctgttc aatgcaccac tgcctgaacg cttccccttc cagtaaagaa
    70141 aactcatccc gatgtttttt ccaccagctt cgacgcactc tgacaacgct catttcccat
    70201 gcgtgagcac cgttggcata aggcttcacc acactggcaa tacaggtagc cagccacagg
    70261 gaaacagact cctccgccag acgtgtcgac agcttttccg gaaggtaatc gttgatattg
    70321 gcggcatagc caggcctgaa gttcagcaca aactttttag ccattgcgcg atcgcagtaa
    70381 tatttgccca cttgctcctg ctcgctgcgg gcaaatcctt ccggcattac cacgtcctca
    70441 ccgtagactg attcaataag aaggcgggct gcgtgtggca tttgaatagc gccttgctca
    70501 cgcagtacac gctgcgtcag ccagattcgt ccatgatcgg gatagacata tgcactgtta
    70561 cgcatggcac tgccgaacca ttcgtcacct ggagcgtcgt cccagacggg ggccagaatc
    70621 agcaattcag gaggggaacg ctcgtctttt ccgtcacgct ttaactgacc attaatatcg
    70681 cggatatgcc gctgtaatcg ccccgctcgc tggatcagca aatcaacagg ggccaggtcg
    70741 gaaatcattt cgtccatatc gcaatcaacg ctcgactcta agacctgagt acaaatgagg
    70801 acttttccgg cacgctgtga gctatcttct ttaccgaagc gtgccagcgt ttccgtttca
    70861 attcgctggc gatcgctaaa agcaaagcgg ctatgaaaca gagaaaggct ggaagcagga
    70921 atgacgccgc gggcaagcaa ctgacgataa accttaatag cgtcatcgac agaattccgg
    70981 atccaggcga tgcatttccc ctgacttact gccgattcga tacgcgcaat acattcttgt
    71041 tcgctatgaa gccaacccac gctcacgcta cgctcaacgt ctttgcgcgt cgctacccgg
    71101 tgtgaatgca catcggattt cgtaacgtgc gtcagccagg ggtaatcatc cttttccagg
    71161 aacggagctt cttgctggcc ctctgtacca cgcgcaaagg cagcaacgag tttgtcgcac
    71221 tgctgttgag ataacgtggc agaaagcaaa atgacgctgt ttccgccacg cgcctgccgc
    71281 tcgatcagcc cttcaagaat gcatgacatg taagcgtcac aggcatggat ctcatcagcc
    71341 agcaggattt tgttactcag tcccagaagc cgcagattat tatgtttgaa cggcatcaca
    71401 gccatcatcg cctgatccag cgtgccgacg ccaatttcag ccagtagcgc cttcttgtta
    71461 ctgtcggcaa accaggccgc acatccctga ctgaacgttt gttcatccgg ttcttctgac
    71521 ccgactaaat caccggacca gagtgattca ttaaagcggt ccattaatgt tcgggcactg
    71581 tgtgccagca ccaggctggg gcgggactct ggcgaataga aagcaagcca ggttttgacc
    71641 agtcgatcgt acatggcatt ggccgttgcc attgttggca ggccaaaaaa caaaccctgc
    71701 gctttacccg cagccatcaa cctgtgcgcc aggataagcg ccgcttccgt tttacctgcg
    71761 ccagtcacat cttccagaat aaataactgt ggccctggct ggctgatatc cagatccagc
    71821 accttttgct gtaacggtgt cggattctca ataaaaggaa acagcgtatt aattccggtg
    71881 aaaggcgcga cttttgcttt tagaggaaag acggttaagg cgttttgagc ctgaactaaa
    71941 gttttctgcc agtaaccttt aatatccatt gggtgtgcga cgcgtggaaa aaatcgcgtt
    72001 gacgaacccg tccagtctgc gagcacgacg gttgcagaga tataccagga aaggtgtttt
    72061 ataagttcaa tgccctcatc atcatcccag aatgcgggga tctctatgag cggaaacagt
    72121 ggtttgattt caagaagaaa atctcgcgcg gcagctttgt cttcaggcag aaaattatcc
    72181 agttcatcaa tacggtcagg cgggcgacca tgatgcccgg tagttatggg catccacatc
    72241 tccatcaccc gtttaagttt gcgcggagag agtgaagatg aaggaagcaa ttcttcgtat
    72301 tcacttaaat aatgatgcca cagccagtag cccagcgttg aatgagagat cttttcgtaa
    72361 ttctttcttg cgccttccgg aaccttgagt tgtgggtgca ggtaaagttg ctgaaaagag
    72421 cgggcaaatt ttccagtatc gtgccagcac aatagccagg cgaaaaattg tgctgcctgc
    72481 tccgtatcag cgaaacctag ttgacgaaaa tagtcagtca gcccgaagca attgctttta
    72541 accattaaat agcccatcgc ggctacatcc agcgaatgcc agcaaagaag gtgatagtcg
    72601 tcgcccccgt ctttctcgcc gcgtcgggtt tttccccaga aatcaaaaaa agtcacaata
    72661 ttttt
//
LOCUS       DACAOP010000011        71849 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.011, whole genome shotgun sequence.
ACCESSION   DACAOP010000011 DACAOP010000000
VERSION     DACAOP010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 71849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71849
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.011"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            221..787
                     /gene="mntP"
                     /locus_tag="IT892_000821"
     CDS             221..787
                     /gene="mntP"
                     /locus_tag="IT892_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HAP3134061.1"
                     /translation="MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFG
                     AVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRR
                     HGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGS
                     IIGKKAEILGGLVLIGIGVQILWTHFHG"
     gene            complement(784..1593)
                     /gene="rlmA"
                     /locus_tag="IT892_000822"
     CDS             complement(784..1593)
                     /gene="rlmA"
                     /locus_tag="IT892_000822"
                     /EC_number="2.1.1.187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(745)-N(1))-methyltransferase"
                     /protein_id="HAP3134062.1"
                     /translation="MSFSCPLCHQPLSREKNSYICPQRHQFDMAKEGYVNLLPVQHKR
                     SRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLRERLDDKATAVLDIGCGEGYYTHA
                     FADALPEITTFGLDVSKVAIKAAAKRYPQVTFCVASSHRLPFSDTSMDAIIRIYAPCK
                     AEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLEGFTLQQSAELCY
                     PMRLRGDEAVALLQMTPFAWRAKPEVWQTLAAKEVFDCQTDFNIHLWQRSY"
     gene            complement(1759..1968)
                     /gene="cspE"
                     /locus_tag="IT892_000823"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(1759..1968)
                     /gene="cspE"
                     /locus_tag="IT892_000823"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HAP3134063.1"
                     /translation="MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTL
                     AEGQNVEFEIQDGQKGPAAVNVTAI"
     gene            complement(1981..2124)
                     /locus_tag="IT892_000824"
     CDS             complement(1981..2124)
                     /locus_tag="IT892_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YobF family protein"
                     /protein_id="HAP3134064.1"
                     /translation="MCGIFSKEVLSKHVDVEYRFSAEPYIGASCSNVSVLSMLCLRAK
                     KTI"
     gene            complement(2794..3081)
                     /locus_tag="IT892_000825"
     CDS             complement(2794..3081)
                     /locus_tag="IT892_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134065.1"
                     /translation="MNEVVNSGVMNIASLVVSVVVLLIGLILWFFINRASSRTNEQIE
                     LLEALLDQQKRQNALLRRLCEANEPEKADKKTVESQKSVEDEDIIRLVAER"
     gene            complement(3156..3299)
                     /gene="mgrB"
                     /locus_tag="IT892_000826"
     CDS             complement(3156..3299)
                     /gene="mgrB"
                     /locus_tag="IT892_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP/PhoQ regulator MgrB"
                     /protein_id="HAP3134066.1"
                     /translation="MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQF
                     IPW"
     gene            3458..3697
                     /locus_tag="IT892_000827"
     CDS             3458..3697
                     /locus_tag="IT892_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134067.1"
                     /translation="MRFIIRTVMLIALVWIGLLLSGYGVLIGSKENAAGLGLQCTYLT
                     ARGTSTVQYLHTKSGFLGITDCPLLRKSNIVVDNG"
     gene            complement(3841..4632)
                     /gene="kdgR"
                     /locus_tag="IT892_000828"
     CDS             complement(3841..4632)
                     /gene="kdgR"
                     /locus_tag="IT892_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator KdgR"
                     /protein_id="HAP3134068.1"
                     /translation="MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMS
                     KSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMRELSR
                     LTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
                     KQILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFG
                     VVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQIGYHDYPF"
     gene            4809..6182
                     /locus_tag="IT892_000829"
     CDS             4809..6182
                     /locus_tag="IT892_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416342.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3134069.1"
                     /translation="MPKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIAT
                     DLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSD
                     SLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
                     AAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLL
                     ITALSGFAQGQSLTLIAAELVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICT
                     SVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAG
                     LLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRE
                     RSGGASGMLGTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILAVIAACVSGLRI
                     TQPRSRA"
     gene            complement(6228..7109)
                     /gene="htpX"
                     /locus_tag="IT892_000830"
     CDS             complement(6228..7109)
                     /gene="htpX"
                     /locus_tag="IT892_000830"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014229823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HAP3134070.1"
                     /translation="MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGF
                     GGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAP
                     DINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVN
                     TFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFS
                     RHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMALCINGKSKSLSELFMTH
                     PPLDKRIEALRTGEYLK"
     gene            complement(7301..9349)
                     /gene="prc"
                     /locus_tag="IT892_000831"
     CDS             complement(7301..9349)
                     /gene="prc"
                     /locus_tag="IT892_000831"
                     /EC_number="3.4.21.102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy terminal-processing peptidase"
                     /protein_id="HAP3134071.1"
                     /translation="MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATV
                     SERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGD
                     ELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
                     ELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAF
                     AREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAI
                     SVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLT
                     RERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDL
                     RSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFS
                     ASASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTI
                     QKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTA
                     FEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRL
                     ARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
                     "
     gene            complement(9369..10067)
                     /gene="proQ"
                     /locus_tag="IT892_000832"
     CDS             complement(9369..10067)
                     /gene="proQ"
                     /locus_tag="IT892_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone ProQ"
                     /protein_id="HAP3134072.1"
                     /translation="MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVD
                     RVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQ
                     LEEAKARVQAQRAEQQAKKREAAATAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQK
                     PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLN
                     SGMSLIVRAEHLVF"
     gene            complement(10164..10661)
                     /locus_tag="IT892_000833"
     CDS             complement(10164..10661)
                     /locus_tag="IT892_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416346.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAP3134073.1"
                     /translation="MNKTEFYADLNRDFNALMAGETSFLATLANTSALLYERLTDINW
                     AGFYLLEDDTLVLGPFQGKIACVRIPVGRGVCGTAVARNQVQRIEDVHVFDGHIACDA
                     ASNSEIVLPLVVKNQIIGVLDIDSTVFGRFTDEDEQGLRQLVAQLKKVLATTDYKKFF
                     ASVAG"
     gene            10791..12074
                     /gene="yebS"
                     /locus_tag="IT892_000834"
     CDS             10791..12074
                     /gene="yebS"
                     /locus_tag="IT892_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity lipid transport subunit YebS"
                     /protein_id="HAP3134074.1"
                     /translation="MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEIN
                     SHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLGIRIDANV
                     MQGIWQMTKQGDAITGSMVFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLK
                     EWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFY
                     PQRPATRRDEKLRVCLGCHFTGYPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVL
                     LLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIASILVPFTKVIVMFT
                     LLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAA
                     FYFGAAVILTILAVEWLDSRLLWDAHESGNARFDD"
     gene            12043..14676
                     /gene="yebT"
                     /locus_tag="IT892_000835"
     CDS             12043..14676
                     /gene="yebT"
                     /locus_tag="IT892_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-binding membrane homeostasis protein YebT"
                     /protein_id="HAP3134075.1"
                     /translation="MSQETPASTTEAQIKNKRRISPFWLLPFIALMIASWLIWDSYQD
                     RGNTVTIDFMSADGIVPGRTPVRYQGVEVGTVQDISLSDDLRKIEVKVSIKSDMKDAL
                     REETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKEQDHFVALDTQPKYRLDNGD
                     LMIHLQAPDLGSLNSGSLVYFRKIPVGKVYDYAINPNKQGVVIDVLIERRFTDLVKKG
                     SRFWNVSGVDANVSISGAKVKLESLAALVNGAIAFDSPEESKPAEAEDTFGLYEDLAH
                     SQRGVIIKLELPSGAGLTADSTPLMYQGLEVGQLTKLDLNPGGKVTGEMTVDPSVVTL
                     LRENTRIELRNPKLSLSDANLSALLTGKTFELVPGDGEPRKEFVVVPGEKALLHEPDV
                     LTLTLTAPESYGIDAGQPLILHGVQVGQVIDRKLTSKGVTFTVAIEPQHRELVKGDSK
                     FVVNSRVDVKVGLDGVEFLGASASEWINGGIRILPGDKGEMKASYPLYANLEKALENS
                     LSDLPTTTVSLSAETLPDVQAGSVVLYRKFEVGEVITVRPRANAFDIDLHIKPEYRNL
                     LTSNSVFWAEGGAKVQLNGSGLTVQASPLSRALKGAISFDNLSGASASQRKGDKRILY
                     ASETAARAVGGQITLHAFDAGKLAVGMPIRYLGIDIGQIQTLDLITARNEVQAKAVLY
                     PEYVQTFARGGTRFSVVTPQISAAGVEHLDTILQPYINVEPGRGNPRRDFELQEATIT
                     DSRYLDGLSIIVEAPEAGSLGIGTPVLFRGLEVGTVTGMTLGTLSDRVMIAMRISKRY
                     QHLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQEGK
                     HFLLQESEPKEWREWGTALPK"
     gene            14756..16195
                     /gene="rsmF"
                     /locus_tag="IT892_000836"
     CDS             14756..16195
                     /gene="rsmF"
                     /locus_tag="IT892_000836"
                     /EC_number="2.1.1.178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1407)-C(5))-methyltransferase
                     RsmF"
                     /protein_id="HAP3134076.1"
                     /translation="MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVN
                     TLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEA
                     SSMLPVAALFADGNAPQRVMDVAAAPGSKTTQISARMNNEGAILANEFSASRVKVLHA
                     NISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESN
                     QEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDAVEFLPLGD
                     LFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPFSPVKD
                     REAGQIRQAATGVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHN
                     KGYRWQHEAVIALASPDNMNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPI
                     GLAKRIGSRLKNSYPRELVRDGKLFTGNA"
     gene            16313..16549
                     /locus_tag="IT892_000837"
     CDS             16313..16549
                     /locus_tag="IT892_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1480 family protein"
                     /protein_id="HAP3134077.1"
                     /translation="MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAW
                     DAETSIPALLNGEHSVLYRTRYDQQSDAWIMRLA"
     gene            16570..16845
                     /locus_tag="IT892_000838"
     CDS             16570..16845
                     /locus_tag="IT892_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebW family protein"
                     /protein_id="HAP3134078.1"
                     /translation="MAGYLSWLFPRCKISPKLNGTAPHFGDEMFALVLFVCYLDGGCE
                     DIVVDVYNTEQQCLYSMSDQRIRQGGCFPIEDFIDGFWRPAQEYGDF"
     gene            complement(16846..17502)
                     /gene="pphA"
                     /locus_tag="IT892_000839"
     CDS             complement(16846..17502)
                     /gene="pphA"
                     /locus_tag="IT892_000839"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416352.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HAP3134079.1"
                     /translation="MKQPAPVYQRIAGHQWRHIWLSGDIHGCLEQLRRKLWHCRFDPW
                     RDLLISVGDVIDRGPQSLRCLQLLEQHWVCAVRGNHEQMAMDALASQQMSLWLMNGGD
                     WFIALADNQQKQAKTALEKCQHLPFILEVHSRTGKHVIAHADYPDDVYEWQKDVDLHQ
                     VLWSRSRLGERQKGQGITGADHFWFGHTPLRHRVDIGNLHYIDTGAVFGGELTLVQLQ
                     "
     gene            complement(17898..18239)
                     /locus_tag="IT892_000840"
     CDS             complement(17898..18239)
                     /locus_tag="IT892_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebY family protein"
                     /protein_id="HAP3134080.1"
                     /translation="MMKKSILAFLLLTSSAAALAAPQVITVSRFEVGKDKWAFNREEV
                     MLTCRPDNALYVINPSTLVQYPLNDIAQKEVASGKTNAQPISVIQIDDPNNPGEKMSL
                     APFIERAEKLC"
     gene            complement(18252..19124)
                     /gene="copD"
                     /locus_tag="IT892_000841"
     CDS             complement(18252..19124)
                     /gene="copD"
                     /locus_tag="IT892_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis membrane protein CopD"
                     /protein_id="HAP3134081.1"
                     /translation="MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLAKRFL
                     RLQQHAAVWSLISATAMLAVQGGLMGTGWTDVFSPNIWQAVLQTQFGGIWLWQIVLAL
                     VTLIVALMQPRNMPRLLFMLTTAQFILLAGVGHATLNEGVTAKIHQTNHAIHLICAAA
                     WFGGLLPVLWCMQLIKGRWRHQAIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPT
                     LTTYWGQLLLLKAILVMIMVVIALANRYVLVPRMRQDEDRAAPWFVWMTKLEWAIGAV
                     VLVIISLLATLEPF"
     gene            complement(19128..19502)
                     /gene="yobA"
                     /locus_tag="IT892_000842"
     CDS             complement(19128..19502)
                     /gene="yobA"
                     /locus_tag="IT892_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopC domain-containing protein YobA"
                     /protein_id="HAP3134082.1"
                     /translation="MASTARSLRYALAILTTSLVTPSVWAHAHLTHQYPAANAQVTAA
                     PQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKRNEQDQKQLIVPLADSLKPGTYT
                     VDWHVVSVDGHKTKGHYTFSVK"
     gene            19641..19871
                     /locus_tag="IT892_000843"
     CDS             19641..19871
                     /locus_tag="IT892_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit theta"
                     /protein_id="HAP3134083.1"
                     /translation="MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQ
                     PEHLRSWFRERLIAHRLASVNLSRLPYEPKLK"
     gene            19973..20629
                     /locus_tag="IT892_000844"
     CDS             19973..20629
                     /locus_tag="IT892_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HAP3134084.1"
                     /translation="MSFWKVAAAQYEPRKTSLTEQVAHHLEFVRAAARQQCQLLVFPS
                     LSLLGCDYSRRALPAPPDLSLLDPLCYAATTWRMTIIAGLPVEYNDRFIRGIAVFAPW
                     RKTPGIYHQSHGACLGRRSRTITVVDEQPQGMDMDPTCSLFTTGQCLGEPDLLASARR
                     LQFFSHQYSIAVLMANARGNSALWDEYGRLIVRADRGSLLLVGQRSSQGWQGDIIPLR
                     "
     gene            20653..21315
                     /gene="exoX"
                     /locus_tag="IT892_000845"
     CDS             20653..21315
                     /gene="exoX"
                     /locus_tag="IT892_000845"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease X"
                     /protein_id="HAP3134085.1"
                     /translation="MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPIS
                     PQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKL
                     ARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
                     MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLE
                     NT"
     gene            complement(21312..23372)
                     /gene="ptrB"
                     /locus_tag="IT892_000846"
     CDS             complement(21312..23372)
                     /gene="ptrB"
                     /locus_tag="IT892_000846"
                     /EC_number="3.4.21.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase B"
                     /protein_id="HAP3134086.1"
                     /translation="MLPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQEN
                     SYGHRVMASQQALQDRILKEIIDRIPQREVSAPYIKNGYRYRHIYEPGCEYAIYQRQS
                     AFSEEWDEWETLLDANKRAAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNL
                     ETGNWYPELLDNVEPSFVWANDSWIFYYARKHPVTLLPYQVWRHAIGTPASQDKLIYE
                     EKDDTYYVSLHKTTSKHYVVIHLASATTSEVRLLDAEMADAEPFVFLPRRKDHEYSLD
                     HYQHRFYLRSNRHGKNFGLYRTRMRDEQQWEELIPPRENIMLEGFTLFTDWLVVEERQ
                     RGLTSLRQINRKTREVIGIAFDDPAYVTWIAYNPEPETARLRYGYSSMTTPDTLFELD
                     MDTGERRVLKQTEVPGFYAANYRSEHLWIVARDGVEVPVSLVYHRKHFRKGHNPLLVY
                     GYGSYGASIDADFSFSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKKNTFNDY
                     LDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVDVVTTML
                     DESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNVTAQAYPHLLVTTGLHDSQVQYWE
                     PAKWVAKLRELKTDDHLLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGTLPA
                     TPAD"
     gene            complement(23581..24240)
                     /locus_tag="IT892_000847"
     CDS             complement(23581..24240)
                     /locus_tag="IT892_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HAP3134087.1"
                     /translation="MANWLNQLQSLLGQSSSSTSSSADQGLVKLLVPGALGGLAGLLV
                     ANKSARKLLTKYGTNALLVGGGAVAGTVLWNKYKDKIRAAHQDEPQFGAQSTPLDERT
                     ARLILALVFAAKSDGHIDAKERAAIDQQLRGAGVEEQGRVLIEQAIEQPLDPQRLATG
                     VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQDVRDGIERDLEQQKRTLA
                     E"
     gene            complement(24567..24923)
                     /gene="yebF"
                     /locus_tag="IT892_000848"
     CDS             complement(24567..24923)
                     /gene="yebF"
                     /locus_tag="IT892_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310584.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YebF"
                     /protein_id="HAP3134088.1"
                     /translation="MKKRGAFLGLLLVSACASVFAANNETSKSVTFPKCEGLDAAGIA
                     ASVKRDYQQNRVARWADDQKIVGQADPVAWVSLQDIQGKDDKWSVPLTVRGKSADIHY
                     QVSVDCKAGMAEYQRR"
     gene            complement(24990..25280)
                     /gene="yebG"
                     /locus_tag="IT892_000849"
     CDS             complement(24990..25280)
                     /gene="yebG"
                     /locus_tag="IT892_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein YebG"
                     /protein_id="HAP3134089.1"
                     /translation="MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTN
                     SPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSPQVVGAESEEEDASHAA"
     gene            25414..26592
                     /gene="purT"
                     /locus_tag="IT892_000850"
     CDS             25414..26592
                     /gene="purT"
                     /locus_tag="IT892_000850"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HAP3134090.1"
                     /translation="MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRY
                     ADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVV
                     PCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSS
                     SGKGQTFIRSAEQLAQAWKYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFC
                     APVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVI
                     FSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQN
                     VTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
                     "
     gene            complement(26648..27289)
                     /locus_tag="IT892_000851"
     CDS             complement(26648..27289)
                     /locus_tag="IT892_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAP3134091.1"
                     /translation="MKNWKTSAESILTTGPVVPVIVVKKLEHAVPMAKALVAGGVRVL
                     EVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLK
                     AATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCP
                     TGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL"
     gene            complement(27326..29137)
                     /gene="edd"
                     /locus_tag="IT892_000852"
     CDS             complement(27326..29137)
                     /gene="edd"
                     /locus_tag="IT892_000852"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020244583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HAP3134092.1"
                     /translation="MNPQLLRVTNRIIERSRETRSAYLARIEQAKTSTVHRSQLACGN
                     LAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVG
                     QVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
                     LTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAP
                     GTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWM
                     PIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMA
                     RLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGEL
                     DWREGAEKSLDSNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVV
                     FESQHDVMPAFEAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRCFKIALVT
                     DGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE
                     PHIPDLSASRVGTGRELFSALREKLSGAEQGATCITF"
     gene            complement(29372..30847)
                     /gene="zwf"
                     /locus_tag="IT892_000853"
     CDS             complement(29372..30847)
                     /gene="zwf"
                     /locus_tag="IT892_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAP3134093.1"
                     /translation="MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQLNPDTR
                     IIGVGRADWDKAAYTKVVREALETFMKETIDEGLWDTLSARLDFCNLDVNDTAAFSRL
                     GAMLDQKNRITINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSQEIN
                     DQVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVG
                     IEGRWGYFDKAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDR
                     SNVREKTVRGQYTAGFAQGKKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFY
                     LRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPG
                     LDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVD
                     SITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE"
     gene            31185..32054
                     /locus_tag="IT892_000854"
     CDS             31185..32054
                     /locus_tag="IT892_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP3134094.1"
                     /translation="MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAAMALEA
                     NVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPYVNRNVNEDDSVKSYTGKIFESA
                     MATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYS
                     DDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLARE
                     ATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKES
                     RFDKQLLNLSDDR"
     gene            32182..33624
                     /locus_tag="IT892_000855"
     CDS             32182..33624
                     /locus_tag="IT892_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase II"
                     /protein_id="HAP3134095.1"
                     /translation="MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSP
                     EDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGK
                     GEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
                     GINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDA
                     KIVAKVERAEAVCSQDAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQL
                     NRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAM
                     ARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTA
                     LMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGY
                     LMSGDLVIVTQGDVMSTVGSTNTTRILTVE"
     gene            complement(33755..34726)
                     /gene="lpxM"
                     /locus_tag="IT892_000856"
                     /gene_synonym="msbB"
     CDS             complement(33755..34726)
                     /gene="lpxM"
                     /locus_tag="IT892_000856"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416369.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HAP3134096.1"
                     /translation="METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFR
                     DPILARLGRFAGRLGKSSRRRALINLSLCFPERSEAEREAIVDEMFATAPQAMAMMAE
                     LAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAM
                     FHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSE
                     FVDFFATYKATLPAIGRLMKVCRARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHT
                     IARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK"
     gene            complement(34846..36168)
                     /gene="mepM"
                     /locus_tag="IT892_000857"
     CDS             complement(34846..36168)
                     /gene="mepM"
                     /locus_tag="IT892_000857"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein DD-endopeptidase MepM"
                     /protein_id="HAP3134097.1"
                     /translation="MQQIARSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHRD
                     ATPIVKTIELEQNEIRSLLPEASEPIDQAAQEDEAIPQDELDDKIAGEAGVHEYVVST
                     GDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRE
                     TRTYDRTAANGFKMTSEMQQGEWVNNLLKGTVGGSFVASARNAGLTSAEVSAVIKAMQ
                     WQMDFRKLKKGDEFAVLMSREMLDGKREQSQLLGVRLRSEGKDYYAIRAEDGKFYDRN
                     GTGLAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFAMPQGTPVLSVGDGE
                     VVVAKRSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGP
                     HLHYEVWINQQAVNPLTAKLPRTEGLTGSDRREFLAQAKEIVPQLRFD"
     gene            complement(36184..37116)
                     /gene="znuA"
                     /locus_tag="IT892_000858"
     CDS             complement(36184..37116)
                     /gene="znuA"
                     /locus_tag="IT892_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     ZnuA"
                     /protein_id="HAP3134098.1"
                     /translation="MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIAD
                     GVTETEVLLPDGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPGAKQV
                     TIAQLEDVKPLLMKSIHGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
                     KLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFG
                     LTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMG
                     TLDPLGTNIKLGKTSYSEFLSQLANQYASCLKGD"
     gene            37195..37950
                     /gene="znuC"
                     /locus_tag="IT892_000859"
     CDS             37195..37950
                     /gene="znuC"
                     /locus_tag="IT892_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein ZnuC"
                     /protein_id="HAP3134099.1"
                     /translation="MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKS
                     TLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDIL
                     PALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
                     DLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFG
                     PRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS"
     gene            37947..38732
                     /gene="znuB"
                     /locus_tag="IT892_000860"
     CDS             37947..38732
                     /gene="znuB"
                     /locus_tag="IT892_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease subunit ZnuB"
                     /protein_id="HAP3134100.1"
                     /translation="MIELLFPGWLAGIMLACAAGPLGSFVVWRRMSYFGDTLAHASLL
                     GVAFGLLLDVNPFYAVIAVTLLLAGGLVWLEKRPQLAIDTLLGIMAHSALSLGLVVVS
                     LMSNIRVDLMAYLFGDLLAVTPEDLISIAIGVVIVVAILFWQWRNLLSMTISPDLAFV
                     DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAV
                     LVGMVAVTGGLTFSAVYDTPAGPSVVLCAALLFILSMMKKQAS"
     gene            complement(38879..39889)
                     /gene="ruvB"
                     /locus_tag="IT892_000861"
     CDS             complement(38879..39889)
                     /gene="ruvB"
                     /locus_tag="IT892_000861"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017441950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAP3134101.1"
                     /translation="MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIF
                     IKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLT
                     NLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
                     TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARG
                     TPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKF
                     FGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPE
                     MP"
     gene            complement(39898..40509)
                     /gene="ruvA"
                     /locus_tag="IT892_000862"
     CDS             complement(39898..40509)
                     /gene="ruvA"
                     /locus_tag="IT892_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAP3134102.1"
                     /translation="MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQE
                     AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV
                     EREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAE
                     QEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL"
     gene            complement(40648..40713)
                     /locus_tag="IT892_000863"
     CDS             complement(40648..40713)
                     /locus_tag="IT892_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134103.1"
                     /translation="MYIFITHFFTEYVILKYLLPI"
     gene            40784..41386
                     /locus_tag="IT892_000864"
     CDS             40784..41386
                     /locus_tag="IT892_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebB family permuted papain-like enzyme"
                     /protein_id="HAP3134104.1"
                     /translation="MNINYPAEYEIGDIVFTCIGAALFGQISAASNCWSNHVGIIIGH
                     NGEDFLVAESRVPLSTITTLSRFIKRSSNQRYAIKRLDAGLTERQKQRIVEQVPSRLR
                     KLYHTGFKYESSRQFCSKFVFDIYKEALCIPVGEIETFGELLNSNPNAKLTFWKFWFL
                     GSIPWERKTVTPASLWHHPGLVLIHAEGVETPQPELTEAV"
     gene            complement(41388..41909)
                     /gene="ruvC"
                     /locus_tag="IT892_000865"
     CDS             complement(41388..41909)
                     /gene="ruvC"
                     /locus_tag="IT892_000865"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005068993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HAP3134105.1"
                     /translation="MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSR
                     LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY
                     AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
                     SESRLNLARGRLR"
     gene            complement(41944..42684)
                     /locus_tag="IT892_000866"
     CDS             complement(41944..42684)
                     /locus_tag="IT892_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP3134106.1"
                     /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD
                     ANPRLRAAVDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECL
                     SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
                     DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMR
                     LIDMLEDCDDVQEVYHNGEISDEVAATL"
     gene            complement(42713..43165)
                     /gene="nudB"
                     /locus_tag="IT892_000867"
     CDS             complement(42713..43165)
                     /gene="nudB"
                     /locus_tag="IT892_000867"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HAP3134107.1"
                     /translation="MKDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVE
                     EGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESW
                     FCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA"
     gene            complement(43283..45055)
                     /gene="aspS"
                     /locus_tag="IT892_000868"
     CDS             complement(43283..45055)
                     /gene="aspS"
                     /locus_tag="IT892_000868"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAP3134108.1"
                     /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI
                     VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTII
                     NRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
                     ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD
                     EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE
                     RRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQI
                     DEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMI
                     FFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHP
                     FTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEE
                     EQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE
                     APSFANPTALAELSIQVVKKAENN"
     gene            45365..45931
                     /locus_tag="IT892_000869"
     CDS             45365..45931
                     /locus_tag="IT892_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416381.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP3134109.1"
                     /translation="MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKF
                     RASGQPVFLVRVGWSADYAEALKQPVDAPSPAKVLPENWWQHPAALGATDSDIEIIKR
                     QWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAAS
                     AEQHNNSINHIYPRIARVRSVEEILNAL"
     gene            45928..46746
                     /locus_tag="IT892_000870"
     CDS             45928..46746
                     /locus_tag="IT892_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAP3134110.1"
                     /translation="MIYIGLPQWSHPKWVRLGITSLEEYARHFNCVEGNTTLYALPKP
                     EVVLRWREQTTDDFRFCFKFPATISHQAALRHCDDLVTEFLTRMSPLAPRIGQYWLQL
                     PATFGPRELPALWHFLDSLPGEFNYGVEVRHPQFFAKGEEEQTLNRGLHQRGVNRVIL
                     DSRPVHAARPHSEAIRDAQRKKPKVPVHAVLTATNPLIRFIGSDDMTQNRELFQVWLQ
                     KLAQWHQTTTPYLFLHTPDIAQAPELVHTLWEDLRKTLPEIGAVPAIPQQSSLF"
     gene            46799..47194
                     /locus_tag="IT892_000871"
     CDS             46799..47194
                     /locus_tag="IT892_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134111.1"
                     /translation="MVSALYAVLSALLLMKFSFDVVRLRMQYRVAYGDGGFSELQSAI
                     RIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRS
                     GMSATWCALLLMVLANLWYMPWELVFSLR"
     gene            47235..47978
                     /gene="cmoA"
                     /locus_tag="IT892_000872"
     CDS             47235..47978
                     /gene="cmoA"
                     /locus_tag="IT892_000872"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy-S-adenosyl-L-methionine synthase CmoA"
                     /protein_id="HAP3134112.1"
                     /translation="MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIIS
                     MIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHI
                     DAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGAL
                     VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
                     HNAGFEHSELWFQCFNFGSLVALKAEDAA"
     gene            47975..48946
                     /gene="cmoB"
                     /locus_tag="IT892_000873"
     CDS             47975..48946
                     /gene="cmoB"
                     /locus_tag="IT892_000873"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /protein_id="HAP3134113.1"
                     /translation="MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSN
                     AVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNID
                     TEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQ
                     FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVN
                     EGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVS
                     VTTTEEQRRTEWMVTESLADFLDPHDPGKTVEGYPAPKRAVLIARKP"
     gene            complement(49133..50083)
                     /locus_tag="IT892_000874"
     CDS             complement(49133..50083)
                     /locus_tag="IT892_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HAP3134114.1"
                     /translation="MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILSAGRW
                     GAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPA
                     KGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
                     YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPL
                     NTLKIAWSSTDEQGLEYFHQLKKSGKPVIAIDPIRSETIEFFDDNATWIAPNMGTDVA
                     LMLGIAHTLMTQGKHDKVFLEKYTTGYRKIYGQCTEVNGV"
     gene            complement(50108..51208)
                     /locus_tag="IT892_000875"
     CDS             complement(50108..51208)
                     /locus_tag="IT892_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome C"
                     /protein_id="HAP3134115.1"
                     /translation="MRGKKRIGLLFLLIAVVVGGGGLLLAQKALHKTSDTAFCLSCHS
                     MSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDYLFAKLKASKDIYHEFVSGKIDS
                     DDKFEAHRQEMAETVWKELKATDSATCRSCHSFDAMDIASQSESAQKMHNKAQKDSET
                     CIDCHKGIAHFPPEIKMDDNAAHELESQAATSVTNGAHIYPFKTSHIGELATVNPGTD
                     LTVVDASGKQPIVLLQGYQMQGSENTLYLAAGQRLALATLSEEGIKALTVNGEWQADE
                     YGNQWRQASLQGALTDPALADRKPLWQYAEKLDDTYCAGCHAPIAADHYTVNAWPSIA
                     KGMGARTSMSENELDILTRYFQYNAKDITEKQ"
     gene            complement(51596..52342)
                     /gene="cutC"
                     /locus_tag="IT892_000876"
     CDS             complement(51596..52342)
                     /gene="cutC"
                     /locus_tag="IT892_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025309.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAP3134116.1"
                     /translation="MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLK
                     SVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVD
                     MPRMEKIMAAAGPLAVTFHRAFDMCANPLHTLNNLAELGIARVLTSGQKSDALQGLSK
                     IMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSS
                     DEHADEYSRYIVDGAAVAEMKGIIERHQAK"
     gene            complement(52356..52922)
                     /locus_tag="IT892_000877"
     CDS             complement(52356..52922)
                     /locus_tag="IT892_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416389.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP3134117.1"
                     /translation="MANWQSIDELQDIASDLPRFIHALDELSRRLGLNITPLTADHIS
                     LRCHQNATAERWRRGFEQCGELLSENMINGRPICLFKLHEPVQVAHWQFSIVELPWPG
                     EKRYPHEGWEHIEIVLPGDPETLNARALALLSDEGLSLPGISVKTSSPKGEHERLPNP
                     TLAVTDGKTTIKFHPWSIEEIVASEQSA"
     gene            53138..54871
                     /gene="argS"
                     /locus_tag="IT892_000878"
     CDS             53138..54871
                     /gene="argS"
                     /locus_tag="IT892_000878"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAP3134118.1"
                     /translation="MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGM
                     MAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALAS
                     DRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
                     DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQ
                     SGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKG
                     LAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVL
                     YYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLAD
                     LLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNML
                     AFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLT
                     VVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGL
                     DTLGIETVERM"
     gene            55048..55536
                     /locus_tag="IT892_000879"
     CDS             55048..55536
                     /locus_tag="IT892_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416391.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HAP3134119.1"
                     /translation="MFKFLVLTLGIISCQAYAEDTVIVNDHDISAIKDCWQKNSDDDT
                     DVNVIKSCLRQEYNLVDAQLNKAYGEAYRYIEQVPRTGVKKPDTEQLNLLKKSQRAWL
                     DFRDKECELILSNEDVQDLSDPYSESEWLSCMIIQTNTRTRQLQLYRNSEDFYPSPLT
                     RG"
     gene            complement(55656..56048)
                     /locus_tag="IT892_000880"
     CDS             complement(55656..56048)
                     /locus_tag="IT892_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlhE"
                     /protein_id="HAP3134120.1"
                     /translation="MRTLLAILLFPLLVQAAGEGMWQASSVGITLNHRGESMSSAPLS
                     TRQPASGLMTLVAWRYQLIGPTPSGLRVRLCSQSRCVELEGQSGTTVAFSGIAAAEPL
                     RFIWEVPGGGRLIPPLKVQRNEVIVNYR"
     gene            complement(56048..58126)
                     /gene="flhA"
                     /locus_tag="IT892_000881"
     CDS             complement(56048..58126)
                     /gene="flhA"
                     /locus_tag="IT892_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HAP3134121.1"
                     /translation="MSNLAAMLRLPANLKSTQWQILAGPILILLILSMMVLPLPAFIL
                     DLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLFTTLLRLALNVASTRIILMEGHT
                     GAAAAGKVVEAFGHFLVGGNFAIGIVVFVILVIINFMVITKGAGRIAEVGARFVLDGM
                     PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVI
                     NVVGGLLVGVLQHGMSMGHAAESYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQD
                     VGEQMVNQLFSNPSVMLLSAAVLGLLGQVPGMPNLVFLLFTAGLLGLAWWIRGREQKA
                     PAEPKPVKMAENNTVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRK
                     KFAQEMGFLPPVVHIRDNMDLQPACYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLP
                     GEATVDPAFGLNAIWIESALKEQAQIQGYTVVEASTVVATHLNHLISQHAAELFGRQE
                     AQQLLDRVAQEMPKLTEDLVPGVVTLTTLHKVLQNLLDEKVPIRDMRTILETLAEHAP
                     IQSDPHELTAVVRVALGRAITQQWFPGKDEVHVIGLDTPLERLLLQALQGGGGLEPGL
                     ADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRH
                     IRMTATIGGK"
     gene            complement(58119..59267)
                     /gene="flhB"
                     /locus_tag="IT892_000882"
     CDS             complement(58119..59267)
                     /gene="flhB"
                     /locus_tag="IT892_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HAP3134122.1"
                     /translation="MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVSV
                     IWFGGVSLARRLSGMLSAGLHFDHSIIKDPNLILGQIILLIREAMLALLPLISGVVLV
                     ALISPVMLGGLVFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAILKTILVGSVTG
                     FFLWHHWPQMMRLMAESPITAMGNAMDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKK
                     LRMSRQDIRDEFKQSEGDPHVKGRIRQMQRAAARRRMMADVPKADVIVNNPTHYSVAL
                     QYDENKMSAPKVVAKGAGLVALRIREIGAENNVPTLEAPPLARALYRHAEIGQQIPGQ
                     LYAAVAEVLAWVWQLKRWRLAGGQRPVQPTHLPVPEALDFINEKPTHE"
     gene            complement(59469..60113)
                     /gene="cheZ"
                     /locus_tag="IT892_000883"
     CDS             complement(59469..60113)
                     /gene="cheZ"
                     /locus_tag="IT892_000883"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HAP3134123.1"
                     /translation="MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEA
                     AEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPI
                     DLADARELVTDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIE
                     RQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQDQVDDLLDSLGF"
     gene            complement(60124..60513)
                     /gene="cheY"
                     /locus_tag="IT892_000884"
     CDS             complement(60124..60513)
                     /gene="cheY"
                     /locus_tag="IT892_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheY"
                     /protein_id="HAP3134124.1"
                     /translation="MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALN
                     KLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLEEKLNKIFEKLGM"
     gene            complement(60528..61577)
                     /locus_tag="IT892_000885"
     CDS             complement(60528..61577)
                     /locus_tag="IT892_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator protein-glutamate
                     methylesterase"
                     /protein_id="HAP3134125.1"
                     /translation="MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDL
                     IKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAI
                     DFVTKPQLGIREGMLAYSEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIA
                     IGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGE
                     RVLPGHAYIAPGDRHMELARSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAV
                     GVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVS
                     QQMLAKISAGQAIRI"
     gene            complement(61580..62440)
                     /gene="cheR"
                     /locus_tag="IT892_000886"
     CDS             complement(61580..62440)
                     /gene="cheR"
                     /locus_tag="IT892_000886"
                     /EC_number="2.1.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HAP3134126.1"
                     /translation="MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLAD
                     HKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSGEWQAFINSLTTNLTAFFREAHH
                     FPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTKVL
                     EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHEGLVRVRQELANYVDFAPLNLLAKQY
                     TVPGPFDAIFCRNVMIYFDQNTQQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLR
                     GQTVYALSKD"
     gene            complement(62459..64060)
                     /gene="tap"
                     /locus_tag="IT892_000887"
     CDS             complement(62459..64060)
                     /gene="tap"
                     /locus_tag="IT892_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein IV"
                     /protein_id="HAP3134127.1"
                     /translation="MFNRIRISTTLFLILILCGILQIGSNGMSFWAFRDDLQRLNQVE
                     QSNQQRAALAQTRAVMLQASTALNKAGTLTALSYPADDIKTLMTTARASLTQSTTLFK
                     SFMAMTAGNEHVRALQKETEKSFARWHNDLEHQASWLESNQLSDFLTAPVQGSQNAFD
                     VNFEAWQLEINHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPL
                     AIIGSHFDSIAAGNLARPIAVYGRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIG
                     IAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTAQ
                     AGGVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGF
                     AVVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMIDIVSSVTRVND
                     IMGEIASASEEQQRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRV
                     AVFPLEEHEVARHESVQLQIAPVVS"
     gene            complement(64106..65767)
                     /gene="tar"
                     /locus_tag="IT892_000888"
     CDS             complement(64106..65767)
                     /gene="tar"
                     /locus_tag="IT892_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein II"
                     /protein_id="HAP3134128.1"
                     /translation="MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSN
                     QLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAAT
                     HYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNA
                     MGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLT
                     PLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIY
                     AGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDT
                     AQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR
                     GFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRV
                     TDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQ
                     AVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF"
     gene            complement(65912..66415)
                     /gene="cheW"
                     /locus_tag="IT892_000889"
     CDS             complement(65912..66415)
                     /gene="cheW"
                     /locus_tag="IT892_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HAP3134129.1"
                     /translation="MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQ
                     VTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVV
                     DGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
                     SAASEVA"
     gene            complement(66436..68400)
                     /gene="cheA"
                     /locus_tag="IT892_000890"
     CDS             complement(66436..68400)
                     /gene="cheA"
                     /locus_tag="IT892_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HAP3134130.1"
                     /translation="MSMDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIF
                     RAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQL
                     DAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQSPR
                     RIILSRLKAGEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEA
                     DQITFETVEVSPKISTPPVLKLAAEQAPTGRVEREKTTRSNESTSIRVAVEKVDQLIN
                     LVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFS
                     RYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKR
                     LAAGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEV
                     AMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGTGTTIRILLPLT
                     LAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIVELWK
                     VFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAAT
                     ILGDGSVALIVDVSALQAINREQRMANTAA"
     gene            complement(68405..69331)
                     /locus_tag="IT892_000891"
     CDS             complement(68405..69331)
                     /locus_tag="IT892_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="motility protein MotB"
                     /protein_id="HAP3134131.1"
                     /translation="MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVM
                     WLISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPN
                     IEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPM
                     FRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRA
                     NASRRELMVGGLDSGKVLRVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHE
                     NAESQNEPVSALEKPEVAPQVSVPTMPSAEPR"
     gene            complement(69328..70215)
                     /gene="motA"
                     /locus_tag="IT892_000892"
     CDS             complement(69328..70215)
                     /gene="motA"
                     /locus_tag="IT892_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HAP3134132.1"
                     /translation="MLILLGYLVVLGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGS
                     FIVGNNGKAIKGTLKALPLLFRRSKYTKAMYMDLLALLYRLMAKSRQMGMFSLERDIE
                     NPRESEIFASYPRILADSVMLDFIVDYLRLIISGHMNTFEIEALMDEEIETHESEAEV
                     PANSLALVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYG
                     FISPLATVLRQKSAETSKMMQCVKVTLLSNLNGYAPPIAVEFGRKTLYSSERPSFIEL
                     EEHVRAVKNPQQQTTTEEA"
     gene            complement(70342..70920)
                     /gene="flhC"
                     /locus_tag="IT892_000893"
     CDS             complement(70342..70920)
                     /gene="flhC"
                     /locus_tag="IT892_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HAP3134133.1"
                     /translation="MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLY
                     KELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLY
                     LEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
                     QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV"
     gene            complement(70923..71273)
                     /gene="flhD"
                     /locus_tag="IT892_000894"
     CDS             complement(70923..71273)
                     /gene="flhD"
                     /locus_tag="IT892_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416406.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
                     /protein_id="HAP3134134.1"
                     /translation="MHTSELLKHIYDINLSYLLLVQRMIVQDKASAMFRLGINEEMAT
                     TLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLN
                     DVNQPEEALRKKRA"
BASE COUNT        17256 a        18824 c        17569 g        18200 t
ORIGIN      
        1 tggggagtag ccgatttcca gattccggaa atgtacgtgt caacatactc gttgcaaaac
       61 gtggcacgta cggactgaat actttcagtc aggcgagacc atatgcacat caatcgctat
      121 gcctgcatga acgcgaaaac catcacggct tgttgttcat gtatgcatgt ttgctggggg
      181 cgatgatgtg ttttatggat accccggtca ggacattgtc atgaatatca ctgctactgt
      241 tcttcttgcg tttggtatgt cgatggatgc atttgctgca tcaatcggta aaggtgccac
      301 cctccataaa ccgaaatttt ctgaagcatt gcgaaccggc cttatttttg gtgccgtcga
      361 aaccctgacg ccgctgatcg gctggggaat gggcatgtta gccagccggt ttgtccttga
      421 atggaaccac tggattgcgt ttgtgctgct gatattcctc ggcgggcgaa tgattattga
      481 gggttttcgt ggcgcagatg atgaagatga agagccgcgc cgtcgacacg gtttctggct
      541 actggtaacc accgcgattg ccaccagcct ggatgccatg gctgtgggtg ttggtcttgc
      601 tttcctgcag gtcaacatta tcgcgaccgc attggccatt ggttgtgcaa ccttgattat
      661 gtcaacatta gggatgatgg ttggtcgctt tatcggctca attattggga aaaaagcgga
      721 aattctcggc gggctggtgc tgatcggcat cggcgtccag atcctctgga cgcacttcca
      781 cggttaataa gaacgctgcc agaggtgaat attaaagtcc gtctggcagt cgaacacttc
      841 ttttgctgcc agtgtttgcc agacttctgg cttcgcacgc caggcaaacg gcgtcatctg
      901 caataatgcg acggcttcat caccgcgaag acgcatcgga taacacaact ccgcactctg
      961 ctgtaatgta aaaccttcca gttgttctgc atgaggtgca tgaagatgta cttcattgta
     1021 aatcagcccc ttcagctcca tcaaatgtcg cggtcccggc gtggcagtaa tgacccagcc
     1081 gccgggcttc actactcgtg ctaattcttc tgctttacac ggcgcgtaaa tacgtattat
     1141 ggcgtccata ctggtatcgg aaaacggcaa acggtggctg gaagcgacac aaaaagtgac
     1201 ctgcggatag cgtttcgccg ccgcttttat cgctaccttc gaaacatcca gaccaaacgt
     1261 ggtgatttcg ggcaacgcat cggcaaatgc gtgtgtgtaa tacccttcac cacagccaat
     1321 atccagcacc gccgtggcct tatcatcaag ccgttccctc agttgggcga caattgcatc
     1381 acgcagcggc tgataatgtc cggcatctaa gaatgcgcgg cgtgcttgca tcatttccgc
     1441 gctgtcgccc ggatcacgag accgtttatg ctgaacgggc agcagattga catacccttc
     1501 tttcgccata tcaaactgat gtcgctgggg acagatatag ctgttttttt cacgcgaaag
     1561 aggctgatgg caaagtggac aggaaaaaga catgacaact ccggcaggat actaaaggcc
     1621 gcaagtgtaa cgcgaatcac gcggcgggca aatatccgaa cgccaggagc gaagataaag
     1681 catagtaaaa agcctcgcat tcgacgaggc tttatagcga gattgaagcg tattcacact
     1741 tcagatcagt ggattcgatc agatagctgt tacgttaaca gctgccggac ctttctggcc
     1801 gtcctgaatt tcgaactcaa cgttctgacc ttcagccaga gttttgaagc cattaccctg
     1861 gatagcggag aagtgtacga acacatcttt gctgccatca gccggagtaa tgaagccaaa
     1921 acctttagac tcgttgaacc acttaacctg acctttaatc tttgccattt gaaaaattcc
     1981 ttagattgtt ttcttcgccc gcaggcataa catagataaa actgacacat tactgcatga
     2041 ggcaccaata taaggctcgg cagagaagcg gtattcaacg tcaacgtgtt tactcaggac
     2101 ttctttactg aaaatgccac acataaacag aactgtacct cgtttaaccc gaaatctgtt
     2161 atcacataca acgttaatta tggcaagcca tttttaaaca tgtctcgatc agacgcacaa
     2221 atctcgatac gtcttccact ttttttgcac acttatgcaa cggaatacgc gccgatatat
     2281 cattgtgctt aaccttgcca gttcaggcag atacttaaac tggcgtattt tctaacatag
     2341 ttcaataagt tcagttgttc caggccagtg ggagaagtta ttacatagtg cgtgcaatat
     2401 cacatttttt gctatgcaat gaataaaaag ttatatcact ttttctcata aaacagtcag
     2461 ttaacggcta ttaattaccc taaagagaag tcaatcccca aagggattgt aaatttaaaa
     2521 taagaaaaat tgatgaatga gcaaaaaaat caagagagaa atgtttcgct aataaataat
     2581 accacgctta atcacaaatc cgatgtaaac atcctaataa attaatgggg taaatatctt
     2641 tttctgatat cccgttacgc aaataaataa tatgataatt atttgaagtc agaccagagt
     2701 tttaatttga agcagttgca ccatgacagt gcgtataatc aggatgaatt gagtaaccct
     2761 tcaacgacgg ggttactcaa gattgaggaa ggattatcgt tcggcgacca gacgaataat
     2821 atcttcgtct tcaaccgatt tttgactctc aacggtcttt ttatctgctt tctctggttc
     2881 gtttgcttcg cacaaacgac gtaacagtgc attttgacgt ttttgctgat ccagcaacgc
     2941 ctcaagcagt tcaatctgtt cgttagtccg tgaactggca cgattgataa aaaaccacaa
     3001 gatgagcccg ataagaagaa ccaccaccga tacaaccaaa gacgcaatgt tcatcacgcc
     3061 tgaatttaca acttcgttca tttcaccacc tctgagtaga ggcgctattc taccactgct
     3121 ggagaggaag aaaatctagt gctgaaaaaa tgatatcacc acgggataaa ctggttaatg
     3181 gcacaaattc cgctgaaaaa ttgtacatcc tgatcgcaca tcatgttgaa tacctgcgcc
     3241 caaagcagca agcaagccaa caccacgaca accagaacga cccatcgaaa ctttttcact
     3301 ccaatctccg tttcacctac cttatgtcat taaactagca tgcgttagtt aaacagcgcc
     3361 taactatgtc gatattcgtg ctttttcgga atgagtcgct tgcttcagcg catattgccg
     3421 ctacgattaa gcgaacataa aaagagaaga ggttgtaatg cgattcatca ttcgcacagt
     3481 tatgctgata gcactggtat ggataggatt attactcagc ggatatggcg ttttgattgg
     3541 aagcaaagag aatgccgcag gattaggttt gcaatgtacc tatctgactg ccagaggcac
     3601 cagcacggta caatacttgc acactaaaag tggttttttg gggataacag attgcccgct
     3661 gttacgcaaa agcaatatcg tggtcgataa tggttaaggg caataaataa ccagattctc
     3721 actcctgagt aaaatactct tatagcaagc gcgtttaata taacgccacc ttcaacttta
     3781 tttttctcat gctaaataaa gaacctgtct gtttgatatt ccgacaggtt cttactctca
     3841 tcagaacgga tagtcgtgat aacctatttg ggcagaaatt ttgcgcgctg cggtatgcaa
     3901 cattgcgaca tattcctgta aacgctcttc agagaaacgc aacgtcggga aggagatgct
     3961 caaaccggca atgaccacgc caaagcgatc aaataccggt accgcaatgc atcgcagccc
     4021 ttcttcctgc tcttcattat cttcgccata cccctgctcg cgcacctggt ccagaacggg
     4081 taataacgct tctgtactgg tgatggtccg ctcggtactg cgtttatact ccacgccctc
     4141 aagaatttgc ttcacttcat cgcgatcgcg ccatgccagc agtaccttac caatcgcggt
     4201 gctgtacagc ggattacgac gcccaatccg tgaatacatg cgcaaattgt acatagagtc
     4261 aattttgtga atgtaaacaa tactgtcttc gtccagtgcg ccgaggtgga tagtttcttt
     4321 ggtcaggcgg gagagctcac gcatctggat atctgcgcta cgaattaaat cgacgttttg
     4381 taacgcgcga gcgcccagtt caaacaattt cagggtcagg gaatatttct ccgactcccc
     4441 ttcctgcgcc acataaccta aggttttcat ggtctgtaaa aagcgataaa cggtgctttt
     4501 tgacatcatg acgcgctgcg acagctcggt tatccctatt tcgcgctctt cacccagcgc
     4561 ctgcaaaatg ccaaaaactt ttagcacgga agatacagaa tcaggctgtt tatccagatc
     4621 tgcgttagcc atttatcacc tcattgcgag tgttttataa aaatcagaac tgttttttat
     4681 tataatttcg caccagggtg gtcgcaatcc atcttttgcc ggttagttac aattctgcga
     4741 catccaccgt gaatatcagt gctagaatca tacccctgtt gattattcac caaagatata
     4801 aaattcctat gccaaaagtt caggccgacg gcctgccatt gccccagcga tacggtgcga
     4861 tattaaccat tgtgattggt atttcgatgg ccgtccttga cggcgcaatc gccaacgtcg
     4921 ccctgccaac aatcgccacg gaccttcatg ccacgccagc cagttccatc tgggtagtga
     4981 acgcctatca aatcgccatt gtcatctccc tgctctcgtt ttcgtttctg ggcgatatgt
     5041 ttggctatcg acgtatttat aaatgcggtc tggtcgtttt tctgttgtct tcactgttct
     5101 gcgccctttc tgattcgctg caaatgctca cccttgcgcg tgtcatacaa ggtttcggcg
     5161 gtgcagcgtt gatgagcgtt aataccgcac ttatccgcct gatctatcca caacgttttc
     5221 tgggtagagg gatgggcata aactcgttta ttgttgccgt ctcttctgct gccgggccga
     5281 caattgctgc agcaatcctc tccatcgcat cctggaaatg gttattttta atcaacgtac
     5341 cgttaggtat tatcgccctg cttctggcga tgcgtttttt gccacccaat ggttctcgcg
     5401 ccagtaaacc ccgtttcgac ctgcccagcg ccgtgatgaa cgcgttaacc ttcggcctgc
     5461 ttatcactgc gttgagtggt ttcgctcagg ggcaatcgct gacgttaatt gctgcggaac
     5521 tggtggtaat ggttgttgtt ggtattttct ttattcgccg ccagctttct cttcccgtac
     5581 cgctgctacc ggtggattta ctgcgtatcc cgctgttttc actttctatt tgcacatctg
     5641 tttgctcttt ctgcgcacaa atgctggcaa tggtttccct gcccttttac ctgcaaaccg
     5701 tgctcgggcg tagtgaagtc gaaacaggtt tacttctgac accgtggccg ttagcaacga
     5761 tggtgatggc tccgctggca ggctatttga ttgaacgcgt acatgcagga ttgctggggg
     5821 ctttagggtt gttcatcatg gctgcggggc ttttttccct ggttctgctg cccgcgtcac
     5881 ctgcggatat caatattatc tggccgatga tcttatgtgg tgctggattt ggcttattcc
     5941 agtcacccaa taaccacacc attattacct ccgcgcctcg cgaacgtagc ggtggagcca
     6001 gtggcatgtt aggaacggct cgtctactgg gtcagagtag cggcgcggcg ctggtggcgc
     6061 tgatgctaaa tcagtttgga gataatggta cacacgtctc gctgatggct gcggctattc
     6121 tggcagtgat tgctgcctgt gtcagtggtt tacgtatcac tcagccacga tccagggcat
     6181 aaaaaaagcg cgtcgatcag gacgcgcttt ttagtattta cttcatatta cttcaggtat
     6241 tcacccgtac gcagagcttc aattcgttta tccagcggcg ggtgggtcat gaacaactca
     6301 ctgagcgatt tcgacttacc gttaatgcag agagccatca tgctggttgc ttcttgcggt
     6361 tcatagctgg ttttcaggcg ctgcagcgcg gcaatcattt tctcgcgacc aaccagtttt
     6421 gccgaaccgg catcagcatg gaattcacga tgacgcgaga accacatggt gataatgctc
     6481 gccagaatac caaacaccag ttccagaacc gttgcaaccg caaagtagat cagcgggttg
     6541 ccgttgctct cttcaccttc atcacgattt ccgcccataa aacccgcggc aagctgcgcc
     6601 agaatacggg aaataaagat aacgaaggtg ttcaccacgc cctgaatcag cgtcatggtg
     6661 accatatcac cattggcgat gtggctgatt tcgtgagcaa ttaccgcctc ggcttcatcc
     6721 gggctcatgt tctgcagcaa accggtgctg acagcaacca gagaggcatc acggcgcgca
     6781 ccggttgcaa aagcgttgat gtccggcgca tggtagatag ccacttgcgg catagcgatc
     6841 cccgcctgac gagcctgggt tgctacagta ttgaccagcc aacgttccct ttcgttacgc
     6901 ggttgctcga tcacttcccc gccaacagat cgtaatgcca tccatttgga catcagaagc
     6961 gaaacgaagg aaccaccaaa accgaacagc aaggccatga tcatcagccc ctgaacgctg
     7021 ctcgactgta tccctgtcag gctcagtacc agcccgaaaa cgaccattac ggccaggttc
     7081 gttagcagga agagcgcgat tcgcatcata attttctttt tacctcagtt taacaaaacg
     7141 caatatgcga tacccacatc gtatgggtta cgcgactatt ttcaagtctg gatagtgcgt
     7201 aagtcaccag aaagacacaa ctttacattt tgtagcatct gatttacggc atcttgtcgc
     7261 tgttaaaaaa tcaggcacaa tttcttgtgc ctgattgata ttacttgacg ggagcgggtt
     7321 gttccgcggg tctggctttt tcaagcttcg ccagatcgag tgcgatattc accgtctcat
     7381 ccagataagg atccggctcc tggtaatctt tcggtagatc atccagtttc ttcaactccg
     7441 gtttaccttc gcgtttaaag cgttcgttca aacgcgccag acgcgtcgca tcatcttcat
     7501 tattctcttt ctcacgcaca gcgtaattca gagaaacgat attgcgcttg tccttcatag
     7561 cgttgaagcg cgcgatatcc ttcatgatgt tctggaactc aggatctttc gcgatacgcg
     7621 cattatgttc cttcagcagc tccggttcaa aggccgttaa atctcctgat ttcacataag
     7681 tcgcggcatc aatgctatcc cacggcagcg cgttatcttc gaatttctca cccgtttccg
     7741 tttcttcatt acccgtcggc atgatgatgt ctggcgttac gcctttacgt tgcgtactgc
     7801 cgccgttaac gcgatagaat ttctggatcg tgtactgcac agaacccagc gctggccatt
     7861 caggacgtaa catctgatcg taaatacggt tcaatgaacg gtattgctga acggtgcctt
     7921 taccaaacgt cggttcaccc acaaccagcg cacgaccgta atcctgcatt gccgcggcaa
     7981 agatttctga agccgaagca ctgaagcggt caaccagcac caccagcggg cctttataga
     8041 aaacctgtcc gtcggtatcg ctatcttcac gaaccttgcc gttgttatcg cggacctgaa
     8101 caatgggacc cgcaggaata aacagaccgg agagcgatac ggcttcagtt aacgccccac
     8161 cgccattgct acgcaggtcg atgatgacgc tgctgacatt ctgtttttcc agtttctgca
     8221 gttgcacttt gacatcgtct gtcaaaccca catagaagcc cggaatatcc agcacgccga
     8281 ctttctcttt accgacggtc ttcaccgaca ttttaaccgc gcggtcttcg agacgaatac
     8341 gttcacgggt caacgttaca gtacgggtct tggtcccttt accagcaggt aaaatttcca
     8401 gacgaacttt actgcccttc ggccctttaa ttaaggcaac cacatcatca agacgccagc
     8461 caatcacgtc aaccatcggc ttgcctgttt gaccaacacc gacaattttg tcaccaacgc
     8521 tgatagcttt actcttcgct gccggaccac ctgccaccat cgaattgata acggtgtagt
     8581 catcatccat ttgcagcact gcgccaatac cttccagcga caaactcatt tcagtgttga
     8641 actgttcggt attacgcggg gaaagatagt tggtatgcgg gtcgatttca cgcgcaaacg
     8701 ccgtcattgc cagcgagaaa acatcttcgc tgttggtttg cgccagacga cgaatggcaa
     8761 atttgtagcg gcgagtcagg gtttcacgaa tttctttatc cgtttttcct gtcagcttca
     8821 ggcttaactc gtcgaatttg actttactgt cccacagcgc gttcaactca gcctcgtttt
     8881 tcggccaggg cgctttgctg cggtcaaggt tataagtgtc gttgccggtg aaatccatcg
     8941 gcttttccag taccgacaaa gcgtactggt aacgctcaaa acggcgcttt tgcgccagat
     9001 tgtagagatc gtagaaaacg tcgagtttgc ctgaacgcag ttcatcgcct aactcggttt
     9061 tctttttcgc gaactgttca acatcgcttg ccagcagcac gttgtggctg taatcgagca
     9121 gattcaggta gcggtcaaag attttggccg aaaatgcctg atcgaggtcg aactggcgat
     9181 aatgagaacg ggtgaagcgc gacgttacgc gctcacttac cgtcgcatgc tgcgtctctt
     9241 cctttaatac cggaatttga tcagcacgcg tgatatcttc tacagcgaag gtctggcctg
     9301 ctattgcaag caggccagct aacgcggtaa gcctaaaaaa catgttcatg cctggcccgg
     9361 cctccgtttc agaacaccag gtgttctgcg cgcacaatca aagacatacc cgaattcagc
     9421 tggacgcgga cgccgtcttt ggtgatttct aatacggtgg catccatcgc gttttgaccc
     9481 gctttcacct tcagggcttg tccgacagtc aaagctgaaa tgtcagaaac cggggtgtgc
     9541 tgttcttcgc gaggtgcttt tactgttttt ggcgctttct ctaccggctt ttgcgcacga
     9601 ggtttacgtt cagcgccttc tttgcggcgt ggcgtagtcg gacgtggctt gcgttcgcgg
     9661 cgcggtgcgt cttctttctc accagcagtt gcggcagctt cgcgtttttt cgcttgctgt
     9721 tcagcacgct gtgcctgaac acgcgctttc gcttcttcaa gctgcttgcg agcatgctct
     9781 acatgttgct cgtccagctc accgcatggg ttgccgtcaa gatcgacacg cgttgcgccg
     9841 ggtttaacac cgtaaagata acgccagctc gaagtgtaga gacgtaaagc ggatcgcaat
     9901 tgcgttttgc tcaggttcat ttccccagca acacgatcga ccaaatcctg aaaaataccg
     9961 attttcagcg gacgcgcttc accttccgca ctgaaacagt ggggaaaacg ttcggccaga
    10021 aacgcgatta cttctttact gctattcaac ttaggttgat tttccatgaa atttcctgat
    10081 tacaacggac gtagccaaca agcgcaggca tgaacaggcg tcattataat gacgctatca
    10141 gtaaatgcta cgttatccgt tgattatcct gcgacgctcg caaagaattt tttgtaatcc
    10201 gtcgttgcaa gcactttttt aagctgtgcc acaagctgac gtaagccttg ctcgtcctcg
    10261 tctgtaaagc gaccgaagac ggtactatcg atgtcgagaa caccaataat ctgatttttc
    10321 accaccagcg gcagaacaat ttcagaatta ctcgccgcat cacaggcaat atgcccgtca
    10381 aacacatgaa catcctcgat acgctgcact tgattgcggg caaccgcagt gccgcacacg
    10441 ccgcgcccga cgggtatccg gacacaggca attttgccct gaaatggtcc gagtaccagt
    10501 gtatcgtcct caagcaaata aaaacctgcc cagtttatgt cagtgagacg ctcatataac
    10561 aacgcactgg tgttcgcaag cgttgccaga aaactggttt ctcccgccat cagcgcgtta
    10621 aagtcgcgat ttaaatccgc gtaaaattct gttttgttca ttatataatc acttggttgt
    10681 cttacctgga tctgccagcc tattaaaata agcattaaat gcgttaatgc tcaagatcat
    10741 tcccatcatg ggttaagatt aatgttaatt cttattacat ttggcacgtc atggctctta
    10801 acacaccaca aattacgccg acaaaaaaga taacagtgag ggcaatcggc gaggaactgc
    10861 cgcgtggtga ttaccaacgt tgcccgcaat gtgacatgct gtttagcctg cccgagataa
    10921 attctcatca aagtgcctat tgtccgcgct gtcaggcaaa aattcgtgac gggcgcgact
    10981 ggtcgctaac gcgcctggcg gcaatggcct tcaccatgct gttgcttatg ccgtttgcct
    11041 ggggcgaacc gctgttgcat atctggctgt taggcattcg tattgacgcc aacgttatgc
    11101 aaggcatctg gcaaatgacc aaacagggcg atgcgataac ggggtcgatg gtctttttct
    11161 gcgttattgg tgccccgctc attctggtga cctccatagc ttatttatgg tttggtaacc
    11221 gactgggaat gaatttacgt ccggtactgc tgatgcttga gcgacttaaa gagtgggtaa
    11281 tgctcgatat ctacctggtc ggcattggcg ttgcttctat aaaggtacag gattatgccc
    11341 atatccaggc tggtgtcggc ttgttctctt ttgtggcgtt ggtgatttta acgacggtga
    11401 cgttgtcaca tcttaatgtc gaagaactgt gggagcgatt ttatccgcag cgccccgcta
    11461 cgcgtaggga cgagaaactt cgtgtctgtc ttgggtgcca ttttaccggc tatccagatc
    11521 agcgtggtcg ctgcccgcgt tgccatatcc cgctacgcct gcgtcgccgt catagtctgc
    11581 aaaaatgctg ggcggcgctg ttagcgtcaa tcgttttatt gttacctgcc aacctgttgc
    11641 ctatttctat catttatctg aacggaggac ggcaggaaga tacaattctt tccggaatta
    11701 tgtcgctggc aagtagcaac attgcggttg caggaatcgt gtttatcgcc agtattctgg
    11761 taccgtttac taaagtgatc gtcatgttca ctttactgtt gagcattcat tttaaatgcc
    11821 agcaaggttt acgcacacgc attctgttac tgcggatggt gacctggatt ggtcgctggt
    11881 cgatgctcga cctgtttgtc atatctttaa ccatgtcgct gattaatcgc gatcagatcc
    11941 tcgcttttac tatgggaccg gctgcgtttt atttcggcgc agcggtaatt ttgactattc
    12001 ttgctgtgga atggctggac agccgcttac tttgggatgc acatgagtca ggaaacgccc
    12061 gcttcgacga ctgaagcgca gattaaaaat aaacgccgta tctcaccttt ctggctgctg
    12121 ccgttcatcg cgctaatgat tgccagttgg ctgatttggg acagttatca ggaccggggt
    12181 aataccgtca ccatcgactt tatgtcggcg gatggtattg ttccaggccg tacgcctgtt
    12241 cgttatcagg gcgttgaagt cggaacagtg caggatatca gcctcagcga cgatcttcgt
    12301 aagattgaag tcaaggtcag catcaagtcc gatatgaaag atgcgctgcg cgaagagact
    12361 cagttctggc tggtgacgcc aaaagcatcg ttggcaggtg tctccgggct ggacgccctc
    12421 gtcggtggga actatatcgg catgatgccg ggtaaaggta aagagcagga tcactttgtc
    12481 gcactcgata cccaaccgaa atatcggctg gacaatggcg atctgatgat ccacctgcaa
    12541 gcccccgatc tcggttcgct gaacagcggt tcattggtct atttccgcaa gatcccggtg
    12601 ggaaaagtct acgactatgc catcaatccc aacaagcaag gcgtggtgat tgatgtcctg
    12661 atcgagcggc gttttaccga tctggtgaaa aaaggtagcc gtttctggaa cgtttccggc
    12721 gttgatgcca acgtcagtat cagtggcgcg aaggtgaaac tggaaagcct ggcggcactg
    12781 gttaacggtg cgattgcctt cgattcacca gaagagtcga aacctgccga ggcggaagat
    12841 acctttggtc tgtatgaaga tctggcccac agccagcgtg gcgtaataat aaaactggaa
    12901 ctgccgagtg gggccggatt aaccgccgac tcgacgccgt taatgtatca ggggctggaa
    12961 gtcggacagc tgactaaact ggatttaaat cctggtggta aagtcacagg ggaaatgacc
    13021 gttgatccca gcgtcgttac cctgcttcgt gaaaataccc gcatcgaatt acgcaacccg
    13081 aaattatccc ttagcgatgc taatctcagc gccctgctga ccggcaaaac cttcgagctg
    13141 gtgcccggcg atggcgagcc acgcaaagag ttcgttgttg tgccaggcga aaaagcactg
    13201 ctgcatgaac ctgatgttct gacgctgacc ctgaccgcgc cggaaagtta cggtattgat
    13261 gcgggtcagc cgctcattct tcacggcgtg caggtaggcc aggttatcga tcgtaaactc
    13321 accagcaaag gcgtcacctt taccgtcgcc atcgagcctc agcatcgcga actggtaaaa
    13381 ggcgatagca aatttgtcgt caacagccgt gtcgatgtga aggtggggct ggatggcgtt
    13441 gagtttctcg gtgccagcgc ctcagaatgg atcaatggcg ggatacgtat tctgccgggc
    13501 gataaaggtg agatgaaagc cagctatcca ctgtatgcca atttggaaaa agcgctggag
    13561 aacagcctta gcgatttacc caccacaacc gtgagtttga gtgcagagac gctgccggat
    13621 gtgcaggcag gatcggtagt gctgtaccgt aaatttgaag ttggtgaagt gattaccgtg
    13681 cgtccgcgag ctaacgcgtt tgatatcgat ctgcatatta agccggagta tcgcaacctt
    13741 ctgaccagca atagcgtgtt ctgggcagaa ggcggggcga aagttcagct gaatggtagt
    13801 ggtctgaccg tacaggcatc cccgctctcc agagcattaa agggagccat tagcttcgac
    13861 aacctcagcg gtgccagcgc cagtcagcgt aaaggcgata agcgtattct gtatgcttcc
    13921 gaaacagcgg cccgtgcggt tggcgggcag attacgcttc acgctttcga tgccggaaaa
    13981 ctggcggtcg ggatgccaat tcgctatctc ggtattgata tcgggcaaat ccagacgctg
    14041 gatctgatta ccgcacgcaa tgaagtacag gcaaaggcgg tactttaccc ggaatatgtc
    14101 cagacctttg ctcgcggtgg tacgcgcttc tcagtggtca caccgcaaat ttcggcagct
    14161 ggcgttgagc atcttgatac tatcctccag ccgtatatca acgtcgaacc aggccggggc
    14221 aatcctcgcc gcgactttga attacaagag gccaccatta ctgattcgcg ttacctggat
    14281 ggcttaagca ttattgttga agcgccggaa gccggttcgt taggcatcgg tacgcctgtg
    14341 ctgttccgtg gtctggaagt cggtacggtt acaggaatga cgctggggac attgtcagat
    14401 cgcgtgatga ttgcgatgcg catcagtaaa cgctatcaac acctggtgcg taacaattcc
    14461 gtcttctggt tggcatcggg ttacagtctg gactttggtc tgacgggcgg cgtagtgaaa
    14521 accggcacct ttaaccagtt tatccgtggc ggcatcgcct tcgccacgcc tccgggtacg
    14581 ccactggcac cgaaagccca ggaaggcaaa cacttcctgt tgcaggaaag tgaaccgaaa
    14641 gagtggcgtg aatggggaac tgcgcttccc aaataatgcc cactgctccg gcgtgcctgc
    14701 gccggagcgt ttatgctaaa ctgcgcgcct gtttttttgc cagtggtaca tgctcgtggc
    14761 ccaacacacc gtttatttcc cggacgcctt tctgacacaa atgcgcgaag cgatgccttc
    14821 gacgctctca tttgatgatt ttcttgccgc ctgtcagcgc ccgttgcgcc gcagcattcg
    14881 cgttaatacg ctgaaaatct ccgttgctga tttcctgcaa ttaaccgctc cttatggctg
    14941 gacgcttacg ccaattccgt ggtgtgaaga aggtttctgg attgaacgcg acaatgaaga
    15001 tgcattgcca ttgggtagta ccgccgagca tttaagtggc ctgttttata ttcaggaagc
    15061 cagttcaatg ttgcctgttg ccgccttgtt tgctgacggt aatgcaccac agcgggtgat
    15121 ggatgtcgct gccgcgcctg gctccaaaac gacgcaaatt tccgcgcgga tgaataacga
    15181 aggggcaatc cttgccaatg agttttccgc cagtcgggta aaagtgttac atgccaatat
    15241 cagccgctgt ggtatcagta atgttgcgct cacacatttt gatggccgcg tgtttggtgc
    15301 ggcagtgcca gaaatgttcg atgccatttt gctggacgct ccctgctctg gcgaaggcgt
    15361 ggtgcgtaaa gatcccgatg cgctaaaaaa ctggtcacca gaaagcaatc aggaaatcgc
    15421 agctacacaa cgggagctta tcgacagcgc ctttcatgca ttacgtcctg gtggtacgct
    15481 ggtttactcg acctgtacct taaaccagga agaaaacgaa gccgtttgcc tgtggctgaa
    15541 agagacttac cccgacgcag tagagttttt accacttggc gatctcttcc ctggtgcaaa
    15601 caaagcgctg accgaagaag gctttttgca tgttttccca caaatttacg actgcgaagg
    15661 cttcttcgtt gctcgtctgc gtaaaactca ggcgattccc gccttacccg cccccaaata
    15721 caaagtcggt aattttccgt tcagcccggt gaaagatcgc gaagctggac aaattcgtca
    15781 ggcggctaca ggtgttggct taaactggga tgaaaacctg cgcctctggc agcgtgacaa
    15841 agaactgtgg ttgttcccgg tgggcattga agccctgatc ggtaaagtcc gattttctcg
    15901 gttggggatt aaacttgccg agacgcacaa caaaggttat cgctggcagc atgaagcggt
    15961 tattgctctt gcctcacccg ataatatgaa tgcattcgag ctgacaccgc aggaagcgga
    16021 ggagtggtat cgcgggcgcg atgtttaccc gcaagccgcg ccagtggcgg atgatgtatt
    16081 ggttactttc cagcatcaac cgattggttt agccaaacgg attggttcgc gattgaaaaa
    16141 cagctatccg cgtgaactgg tgcgcgatgg gaaacttttt accggtaacg cctgacagcg
    16201 cacaaaaaaa gcgcactttt tgactggcac attcggctgc ctcaactagg ctgaaaaatg
    16261 gtgcgatcgg actggtcgta ccacaatcgg cagctaaatg gagagcacga agatgaaaac
    16321 cagtgtgcgc ataggcgctt ttgaaatcga cgacggcgaa ttacacggtg aatcgccagg
    16381 tgatcgaacg ttaaccattc cttgtaaatc tgaccccgat ttatgtatgc aactggatgc
    16441 ctgggatgct gaaaccagta tccctgccct gctaaatggc gaacactctg tcctttaccg
    16501 tacccgttac gatcaacaat ctgatgcctg gattatgcgt cttgcctgat ccaaaaagaa
    16561 cccgtcggca tggcgggtta tttgtcctgg ttattccccc gttgtaaaat ctctcctaaa
    16621 cttaacggta cggcaccaca cttcggggat gaaatgttcg cgctggtact ttttgtttgc
    16681 tacctggatg gcggttgtga agatattgtt gtggatgtct acaacacgga acagcagtgt
    16741 ctttattcta tgagcgatca acggatccgc cagggcggtt gttttccgat tgaggatttt
    16801 atagatggtt tctggcgacc tgcacaggag tacggtgatt tttaattatt gcaattgcac
    16861 aagagtcagt tcgcccccaa agacagcacc ggtatcaata taatgcaggt tgccaatatc
    16921 cacgcgatgt cgcaacggtg tatgaccaaa ccagaaatga tcagcacctg taattccctg
    16981 ccctttttgg cgttcaccta atcgcgagcg gctccacaag acctgatgca aatcaacgtc
    17041 cttttgccat tcataaacat catctggata atcggcatga gcaataacat gcttgccggt
    17101 gcgactgtgt acttcaagaa taaagggcaa atgctgacat ttttccagcg ccgttttcgc
    17161 ttgtttctgt tgattatctg ccagcgcaat aaaccagtcg ccgccattca tcaaccacaa
    17221 agacatctgc tgggatgcca gcgcatccat cgccatctgt tcatgattgc ctcttaccgc
    17281 acaaacccaa tgttgttcca gtaactgcag acaacgtaaa ctttgcggcc cacgatcgat
    17341 aacgtctccc actgagataa gtaaatctcg ccacggatca aaacgacaat gccataattt
    17401 gcggcgcaac tgctcaagac aaccgtgtat atcgccagaa agccagatat gtcgccattg
    17461 atgacccgca attctctgat aaacgggcgc aggctgtttc atcaatattt tcctcccgcg
    17521 ctaaagaaca cataatctta acaagaatgt taaaaaacgc tggactcaga cagtagagtg
    17581 tgtgttatgg ttgactataa agtcagcgaa ggaaatgctt ctggctttta acagataaaa
    17641 agagaccgaa cacgattcct gtattcggtc cagggaaatg gctcttggga gagagccgtg
    17701 cgctaaaagt tggcattaat gcaggcttag ttgccttgcc ctttaagaat agatgacgac
    17761 gccaggtttt ccagtttgcg tgcaaaatag tcaataaaaa gcgtggtggt catcagctga
    17821 aatgttaaaa accgcccgtt ctggtgaaag aactgaggcg gtttttttat tggaaatcaa
    17881 aaggctattt taggtaatta acagagtttt tcagctcgtt ctataaacgg tgccagactc
    17941 attttttcgc cgggattgtt aggatcatca atctgaatca ccgaaatggg ttgggcattg
    18001 gtcttcccac tggcaacttc cttttgtgcg atatcgttta aaggatactg cacgagggta
    18061 ctcggattaa taacatacaa agcattatcc ggtcggcaag tcagcatcac ctcttcgcga
    18121 ttaaacgccc atttgtcttt acccacttca aaacgactga cggtaatcac ctgcggtgca
    18181 gccagcgccg ctgcagaact ggtgagtaac agaaacgcca gaatactttt tttcatcatt
    18241 ttcgtaatcc atcaaaaagg ttcgagagtc gcaagcaggc tgatgatcac cagcactacc
    18301 gcacctatcg cccattcgag tttagtcatc cacacaaacc agggtgccgc acgatcttca
    18361 tcctgcctca tgcgcggtac aagaacataa cgattagcca gcgcaatgac caccataatc
    18421 atcaccagga tggctttgag caataagagt tggccccagt aagtcgtaag cgtgggggga
    18481 aatccggtaa tcaacaatgc attaagcacg ccgcttgcca gtacgccgat caccgcaaaa
    18541 tgcccgcacc aggaaaaacg catcagcgcc tgaatagcct ggtgtcgcca acggcctttg
    18601 atgagttgca tacaccagag caccggcagt aatcccccaa accacgccgc cgcacaaatc
    18661 aggtgaatcg cgtgattagt ctgatggatt ttcgctgtta ccccttcatt cagcgtcgca
    18721 tgccccactc ccgccagcag aataaattgc gcggtagtga gcataaacag caaacgtggc
    18781 atattccgcg gttgcataag ggcgacgatc aacgttacga gggcgagaac aatttgccat
    18841 aaccagatgc caccaaactg cgtttgcaaa acagcctgcc aaatgtttgg cgaaaataca
    18901 tctgtccatc ccgttcccat caacccgccc tgaacggcga gcattgcagt ggcactgatc
    18961 aaactccaga cggcagcgtg ctgttgtaaa cgcagaaaac gcttcgccag caagcgacga
    19021 atcgtcaagg gggccagcca ggcaccgtac attgcgaagc caaaaaccag catcagcgag
    19081 gtgaaatgga taaatcgcag cgcgatccag gtaaacgcca gcatgattta tttcacgcta
    19141 aaggtgtagt gtcctttcgt tttatgcccg tccaccgaaa caacatgcca gtcaacggtg
    19201 taggttccgg gtttcagcga atcggccagt ggaacaatca gttgcttttg gtcctgctca
    19261 tttcgcttcg ccggtaatgt tttaatattt tcgttttttg gccccgtgat ttttgcacca
    19321 ctgaatcctg tttcaacacc ttccgagaag tttaaagtga ttgcctgcgg tgcagctgtc
    19381 acttgcgcgt ttgccgcagg atactgatgc gttaaatgcg catgtgccca gacggaaggt
    19441 gtcaccaacg aagtggtcag gattgccagc gcgtagcgaa gggagcgtgc agttgaagcc
    19501 atattatcta ttcctttttg taataacttt tttacagagc ataaccttgt ctaatgtctg
    19561 agtcgaggat catcaattcc ggcttgccat cctggctcac tcttagtaac ttttgcccgc
    19621 gaatgatgag gagattaaga atgctgaaga atctggctaa actggatcaa acagaaatgg
    19681 ataaagtgaa tgtcgatttg gcggcggccg gggtggcatt taaagaacgc tacaatatgc
    19741 cggtgatcgc tgaagcggtt gaacgtgaac agcctgaaca tttgcgcagc tggtttcgcg
    19801 agcggcttat tgcccaccgt ttggcttcgg tcaatctgtc acgtttacct tacgagccca
    19861 aacttaaata aaacttatac agagttacac tttcttacat aacgcctgct aaattatgag
    19921 tattttctaa accgcactca taatttgcag tcattttgaa aaggaagtca ttatgtcgtt
    19981 ctggaaagtt gcagcagcgc aatatgagcc tcgtaaaacc tcactcaccg aacaggtagc
    20041 tcatcatctg gagtttgtga gggccgccgc caggcaacaa tgtcagctgt tagtttttcc
    20101 atcgctttct ttactggggt gtgattattc gcgacgtgcc cttcctgccc cacccgatct
    20161 ctcactgtta gacccgcttt gttatgccgc aacgacctgg cgaatgacca tcattgccgg
    20221 ccttcccgtt gaatataacg atcgctttat tcgtggaatt gcggtgttcg caccgtggcg
    20281 aaaaacgcct gggatctacc atcagagtca tggtgcatgt ctgggccgtc gttccagaac
    20341 catcacggtg gtcgatgaac aaccgcaagg tatggatatg gacccgacct gttcactgtt
    20401 tactacaggg caatgtctgg gagaacccga cctgctggcg tcggcccgtc gcttacaatt
    20461 tttttcacat cagtactcga ttgccgtgct gatggcaaat gcccgtggta acagtgcact
    20521 atgggatgaa tatggtcgtc tcatcgttcg cgccgatcgt ggttcattat tgttagtcgg
    20581 tcagcgttca tcacagggtt ggcaaggcga tatcattcca ttacgctagg ctttttcggc
    20641 ctggagcatg ccatgttgcg cattatcgat acagaaacct gcggtttgca gggagggatc
    20701 gttgagattg cctctgttga tgtcattgac ggaaaaatcg tcaaccccat gagccacctg
    20761 gtgcgccccg atcgtcctat tagtccacaa gcgatggcga ttcatcgcat caccgaagcc
    20821 atggtcgccg ataaaccgtg gattgaagat gtgatcccac actattacgg tagtgaatgg
    20881 tatgtcgcgc ataacgccag ctttgaccgc cgcgtactgc ctgagatgcc cggtgagtgg
    20941 atttgcacta tgaaactggc ccgtcgtttg tggcctggga tcaagtacag caatatggcg
    21001 ttatataaaa cacgcaagct caatgtacag acgccgccgg gcctgcatca tcaccgcgcg
    21061 ttgtatgact gttatatcac cgccgcgttg cttatcgata ttatgaacac ctccggctgg
    21121 acggcagaac agatggccga tatcaccgga cgtccgtcgt tgatgacgac cttcaccttt
    21181 ggcaaatacc gtggcaaagc ggtttccgac gttgccgaac gcgatccggg ctatctgcgc
    21241 tggttattta ataacctgga cagcatgagc ccggagctgc gtttaacact gaaacattat
    21301 ctggaaaata cttagtccgc aggcgtagcg ggtaatgttc cctgcgccag cgcgaccaga
    21361 aaagcatatt ccatcgctac gccttcgtac gatttaaagc gaccagattt accgccatgg
    21421 cctgagtcca tgtcggtaca gagcaataaa agatggtcat cggttttcag ctcgcgcaat
    21481 ttagcgaccc attttgccgg ttcccaatat tgcacctgag aatcgtgcaa accggtcgtt
    21541 accagtaaat gcggataagc ctgtgcggtg acgttgtcat acgggctgta gcttttcatg
    21601 tactcgtaat attgcggatc ctgcgggtta ccccactctt caaactcacc agtggtaaga
    21661 ggaattgatt catcaagcat cgttgttaca acatcaacaa acggtacctg ggcgataacg
    21721 ccgtggaata attccgggcg ttgattaatt gcaacgccca tcaacatgcc ccccgcactc
    21781 ccgcccatcg cataacaaag cgaaggagag ccatagccca gttttaacaa tgcatcgcag
    21841 gcatcaagat aatcattaaa cgtatttttc ttcttcagaa attttccgtc ttcgtaccat
    21901 tgttgcccca gctcaccacc gccgcgaaca tggacaatgg cgtagacaaa gccacgatct
    21961 aacaaactca agcggctaaa actgaaatcg gcatcaatac ttgcgccgta agaaccatag
    22021 ccatacacca gcaacgggtt gtgtcctttg cgaaaatgtt tgcgatggta gaccaacgaa
    22081 accggaactt cgacgccatc acgggcgact atccacaggt gttcactgcg gtaattcgcc
    22141 gcataaaaac caggaacttc cgtttgtttt aatacacgac gctcaccggt atccatatcc
    22201 agttcaaaca aagtgtctgg tgtagtcatg gaagaataac cataacgcaa tcgcgcggtt
    22261 tcaggttctg gattgtaggc aatccaggtc acataggccg gatcatcaaa ggcaatacca
    22321 atgacttccc gggtcttgcg gttaatttgg cgcaaactgg ttaacccgcg ctgacgctct
    22381 tcaaccacca gccagtcggt aaacagcgta aacccttcca gcatgatgtt ttcgcgtggc
    22441 ggaattaact cttcccactg ttgctcatca cgcatacggg tacggtataa gccaaagttt
    22501 ttgccgtggc ggttggaacg cagataaaaa cgatgctggt agtgatcaag gctgtattcg
    22561 tgatctttgc ggcgcggcag aaaaacaaac ggctcggcat cggccatttc cgcgtccagc
    22621 aggcgaactt cactggtggt ggcgctggcc aaatgaatga ctacatagtg cttcgaggtc
    22681 gttttatgca ggctgacgta ataggtatcg tctttttctt cgtagatcag tttatcttgc
    22741 gatgctggcg taccgatggc gtgacgccag acctgataag gcagcagcgt caccggatgc
    22801 ttgcgagcat agtagaaaat ccaggagtca tttgcccaga caaagctggg ttcaacgtta
    22861 tccagcagtt ccgggtacca gttaccagtt tccagattac gaaaacgaat gccgtactgg
    22921 cgtcgggaaa gaaaatcttc tgccagcgcc ataatggtgt tatcgggcgt aatcgccatt
    22981 ccgcccatcg aataaaactc actatgagct gcgcgcttat tggcatcgag caatgtttcc
    23041 cactcatccc actcttcact gaatgccgat tgacgctggt agatagcata ttcacagcct
    23101 ggttcataaa tatgccgata gcggtagcca tttttgatgt agggcgcaga aacttctcgt
    23161 tgcggaatgc ggtcgatgat ttcctttaag atgcgatcct gcaaggcttg ttgtgaggcc
    23221 atcacccgat gaccgtaact attttcttgt tgcaggtagt ccaggacttc tggctgagaa
    23281 cgcgtatcat cccgcagcca gtagtaatta tcgatgcgcg tatcgccatg aagcgtcatg
    23341 gcgtggggaa tgcgggcggc ttttggtagc atgttattgt tctttctggt tgaaacatct
    23401 tataagggtg gcaaaactca ccggggatgc aagcgaaaca ggggagtcat tgcttagatg
    23461 atgacaggta atggcgcgga tatcgaatgt tatgcagaca gagaaaatca gcctgttcaa
    23521 atggctgtgc gattctggat agcccgaaat agtcaacttc aggctatcca gagagcggaa
    23581 ttattccgcc aaagtgcgtt tttgctgttc gagatcgcgt tcaatgccgt cacgaacatc
    23641 ctgggggatt ttcagcgcgt cacccagtgc attcaggtaa ctgcgttcca taaaatggtc
    23701 aatatcaata gccgcgcaac tcaggaaata gatttccagc gcctcttctt cattgcggac
    23761 cccggtagcc aggcgttgtg gatccagcgg ttgttcgatt gcctgctcaa tgagtacacg
    23821 cccctgctct tccacgccgg ctccacgcaa ttgctggtcg attgccgcac gttctttggc
    23881 atcaatatga ccatcacttt tagcggcaaa gaccagcgca aggatcaaac gtgctgtacg
    23941 ctcatccagc ggcgtacttt gcgcgccaaa ctgcggttcg tcctgatgcg ccgcgcgaat
    24001 tttatctttg tatttattcc acagcaccgt acccgctacc gctccgccgc caaccagtaa
    24061 cgcgttggtg ccatatttcg taagaagttt acgtgctgat ttatttgcga ccagcagccc
    24121 agccagtccg cctaatgcgc ctggcactaa cagtttgacc aatccctgat ccgcagacga
    24181 ggaggtagaa gaactgcttt gcccaagcag ggattgcagt tgatttaacc agttagccat
    24241 atttgctcct caataaccat ttttagtgcc tgtagcatag cggatgagga tgtcagaaaa
    24301 tgtatatcga gacaaaagat gcgcaaataa gcggggcggt aggccgttat tcaaagaaat
    24361 tcgcgccagg taaggtattt actgtatatc aggtgataag ggtattttag gtgaaagtag
    24421 tttgtcgttt tgagtggcat tgtttgatgc tgattgcccg atgcgacgct gttgcgtctt
    24481 ctcaggccta cgattgtggt gcgttctggg gcggacaagg cactcgcgcc gcatccgcca
    24541 acagtcaatc gaattatcag aagccattaa cgccgctgat attccgccat tcccgctttg
    24601 cagtccacgc tgacctggta atgaatatcg gcacttttac cacgcacggt tagcggtact
    24661 gaccatttat catctttacc ctgaatgtcc tgcaaactga cccaagccac gggatcggcc
    24721 tgaccgacaa ttttttgatc atctgcccaa cgcgccacgc gattttgttg ataatcacgt
    24781 tttacgctcg cggcaattcc ggcagcatcc agaccttcac actttgggaa agtgaccgac
    24841 ttgctggttt cattattggc agcgaaaact gatgcgcagg cagaaaccaa caacagccct
    24901 aaaaacgccc ctcttttttt catgtttttc tccatagcac aatgattcag gagaaagcat
    24961 ggtacaaatt gtcaggagcg caagttgctt caggccgcgt gtgaggcatc ttcctcttcg
    25021 gattcagcac cgacgacctg tggggacggt aatttgccgg ttttcagaat ggtgctcagc
    25081 acatcttttt gttctgccag ccatagcgaa agggcttcac gttgctcgtc ttccatttgc
    25141 actggagaat ttgtcagcca ggtgtcaagc agatccgccg tatcaagcat tttgtcataa
    25201 gcatcggctt cctttttgct ggtaaacgac attttctctt cgccctcacg aatgactacg
    25261 tatttaactt caaccgccat ttgcagcctc tcataataac tgtgatttta tacagtatat
    25321 ttcttttcgg ttgagaaatc aacatcagca ataaagacac acgcaaacgt tttcgtttat
    25381 actgcgcgcg gaattaatca ggggatattc gttatgacgt tattaggcac tgcgctgcgt
    25441 ccggcagcaa ctcgcgtgat gttattaggc tccggtgaac tgggtaaaga agtggcaatc
    25501 gagtgtcagc gtctcggcgt agaggtgatt gccgtcgatc gctatgccga cgcaccagcc
    25561 atgcatgtcg cgcatcgctc ccatgtcatt aatatgcttg atggtgatgc attacgccgt
    25621 gtggttgaac tggaaaaacc acattatatc gtgccggaga tcgaagctat tgccaccgat
    25681 atgctgatcc aacttgaaga ggaaggactg aatgttgtcc cctgcgctcg cgcaacgaaa
    25741 ttaacgatga atcgcgaggg tatccgtcgc ctggcggcag aagagctgca gctgcccact
    25801 tccacttatc gttttgccga tagcgaaagc cttttccgcg aggcggttgc tgacattggc
    25861 tatccctgca ttgtaaaacc ggtgatgagc tcttccggca aggggcagac gtttattcgt
    25921 tctgcagagc aacttgctca ggcatggaag tacgctcagc aaggcggtcg cgccggagcg
    25981 ggccgcgtaa ttgttgaagg cgtcgttaag tttgacttcg aaattaccct gctaaccgtc
    26041 agcgcggtgg atggcgtcca tttctgtgca ccagtaggtc atcgccagga agatggcgac
    26101 taccgtgaat cctggcaacc acagcaaatg agcccgcttg cccttgaacg tgcgcaggag
    26161 attgcccgta aagtggtgct ggcactgggc ggttatgggt tgtttggtgt cgagctattt
    26221 gtctgtggtg atgaggtgat tttcagtgag gtctcccctc gtccacatga taccgggatg
    26281 gtgacgttaa tttctcaaga tctctcagag tttgccctgc atgtacgtgc cttcctcgga
    26341 cttccggttg gcgggatccg tcagtatggt cctgcagctt ctgccgttat tctgccacaa
    26401 ctgaccagtc agaatgtcac gtttgataat gtgcagaatg ccgtaggcgc agatttgcag
    26461 attcgtttat ttggtaagcc ggaaattgat ggcagccgtc gtctgggggt ggcactggct
    26521 actgcagaga gtgttgttga cgccattgaa cgcgcgaagc acgccgccgg acaggtaaaa
    26581 gtacagggtt aaacccggca aaaaaacgct acaaaaatgc ccgatcctcg atcgggcatt
    26641 ttgactttta cagcttagcg ccttctacag cttcacgcgc cagcttagta atgcggtcgt
    26701 aatcgcccgc ttccagcgca tctgccggaa ccagccagga accaccgatg cacagcacgc
    26761 ttttcagcgc caggtagtca cggtagttag ccggagaaat accacccgtc gggcagaaac
    26821 ggacctggga gaacggaccc gcgatcgcct gcagggcttt cacgccgccg ttagcttcag
    26881 ccgggaagaa tttgaactct ttcaaaccgt agtccatacc cagcatcagt tcggaaacag
    26941 tgctgatccc cggaatcaga ggaatagtcc cttcggtagc agctttcagc agcggctcgg
    27001 tcagacccgg gctaattgcg aactgtgcac ccgcttcagt gacttctgcc agctgctgtg
    27061 gattcagcac cgtaccggca cccacaatcg cttcaggcac ttctttggcg atagcacgga
    27121 tagcgtcaac tgcacactcg gtacgcagag tcacttccag aacgcgcacc ccaccagcaa
    27181 ccaacgcttt tgccatcggc accgcgtgtt ccagtttttt taccacgata accggtacaa
    27241 ccgggccggt ggtcaggatt gattctgcac ttgttttcca gtttttcatc agagttttct
    27301 ctcgcctgat tacaaatttg tcgtcttaaa aagtgataca ggttgcgccc tgttcggcac
    27361 cggacagttt ttcacgcaag gcgctgaata attcacgtcc tgttcccacg cgtgacgcgc
    27421 tcaggtcagg aatgtgcggt tcgcgagcag ccagttccgc ttcgtctacc agcagcgtca
    27481 gttcgcctgt ctgtccattc acacgaatga tgtccccgtc gcgcactttt gccagcagcc
    27541 cgccatcgta ggcttctggt gttacgtgga tagctgacgg cactttacct gaagcgccgg
    27601 agagtcgtcc atcggtaact aacgcaattt tgaaacaccg gtccaataat acaccaagtg
    27661 gcggcatgag tttatgtaat tctggcattc cgttcgcttt tggcccctga tgacggacaa
    27721 caacgacaca atcgcggtcc agcaaacccg cttcaaaggc cggcataacg tcatgctggc
    27781 tttcaaaaac aaccgctggc gcttcaatca cctggttctc aaccggcacg gcagaggttt
    27841 tcataaccgc acggcccagg ttaccgctta acacttttgt cccaccatga tgagagaaag
    27901 gttgttcgaa ggaagcgatc acattgctgt cgagtgattt ttccgcccct tcccgccagt
    27961 ccagttcacc attattcagc catggttcaa gggtataacg agacagacca aaacctgcca
    28021 ccgtattgac atcttcatgc agcaggcctg ctttgagcag ttcacgcacc agaaccggta
    28081 cgccacctgc cgcctggaag tggttaatat cggccggacc gttcgggtag agacgtgcca
    28141 tcagcggtac aacatcagaa aggtcagaga agtcatccca gttaatctga ataccggccg
    28201 cgcgcgccat cgccaccagg tgcatggtgt ggttagtgga accaccggtc gccagcagtg
    28261 caacgatacc gttcaccacc actttctcat cgatcatctt accgatcggc atccattcat
    28321 taccattacc ggtcatgcgt gtaacctgac gcgcagctgc ggcggtcaaa gcatcgcgca
    28381 gcggagaatc cggatgaaca aaagaagagc ctggcaactg catccccata aactccacca
    28441 ccatctggtt ggtgttggca gtaccgtaga aagtacatgt tcccggcgca tggtaagacg
    28501 cggcttctga ctccagtaag gccatgcggt ccactttacc ttcggcataa agctggcgaa
    28561 tacgcacttt ttctttattt ggcaaaccgc ttgccatcgg tccagacggc acaaacaccg
    28621 caggcaaatg accaaacgac agggctgcca tcgtcagacc cgggacaatc ttgtcgcaca
    28681 caccgaggaa cagagcacca tcaaacatgt tatgggacag ccccaccgcc gcagacatcg
    28741 ctatcacttc gcggcttagc agcgacaatt ccattccatc ctgcccctgg gtgacaccat
    28801 cacacatcgc cggaacaccg cccgcaacct gaccaaccgc attcgcttca tgcagggctt
    28861 tacgaatgat ttctggatag tgttcataag gctggtgcgc ggagagcatg tcgttatagg
    28921 aggtgatgat ggcgatattg ttacgcaaca tgcttttcaa agaggctttg tcttctggct
    28981 ggcaggcagc gaaaccgtgt gccaggttac cgcatgccaa ctgcgaacga tgaacggtcg
    29041 aagttttcgc ttgttctatc cgggcgagat aagcagagcg agtctcgcgc gaacgttcaa
    29101 tgattcgatt tgttacgcgt aacaattgtg gattcataaa ggctcctgaa attgagttgt
    29161 cagagcagga tgattcacaa cgcgtttcat tcagaggatt tatgactgaa acgcctgtaa
    29221 ccggagctca tagggcaaaa acgtttcagt cagtgtaata aaaaaagcct cgtgggtgaa
    29281 tccgcacgag gcctgaaagt gtaaaaattg ttctacaatc tgcgcaagat catgttaccg
    29341 gtaaaataac cataaaggat aagcgcagat attactcaaa ctcattccag gaacgaccat
    29401 cacgggtaat catcgccacc gaggcaacgg gtccccaggt tccggcctga tacggtttcg
    29461 gcgcatcatt gtccatcgcc cacgcctcag taatggagtc tacccatttc caggcttctt
    29521 ccacttcgtc gcgacgtaca aacagtgcct gaataccacg catggtttcc agcagcaaac
    29581 gttcataggc atccgccaga tgcgtctgat taaaggtttc tgaatagctc agatccagct
    29641 tggtgatttg caggttatgt ttgtggtcaa ggccaggaac tttattcagt acctggatat
    29701 ccacgccttc atcaggttgc agacggatag tcagtttatt ctgcggcaga tcctgccacg
    29761 attctttaaa cagattcagt tcaggtgttt tgaaatagac cacgacttca gaacatttgg
    29821 tcggcagacg tttaccagta cgcaggtaga atggcacacc ggcccagcgc cagttatcaa
    29881 tgtcgacgcg gatcgccacg aaagtttctg tattgctgct cttgttcgcg ccctcttctt
    29941 ccagatatcc cggcactttt ttgccctggg cgaagcccgc agtatattgc ccgcgtacgg
    30001 ttttttcgcg tacgttggag cggtcgatgc ggcgcagaga cttcagtact ttcacttttt
    30061 catcgcggat gctgtctgcg ctcaggtcag acggcggaga catcgcaatc atgcaaagaa
    30121 tttgcagcag gtggttctgg atcatgtcgc gcatctgacc ggctttatca aaatagcccc
    30181 agcgcccttc gatccccact tcttctgcca cggtaatctc aacatgatca atggtgcgat
    30241 tgtcccagtt attcacaaac agggagttag caaaacgcag cgccaacagg ttcagcaccg
    30301 tttctttacc aagatagtgg tcgatacggt aaacctggca ctcctcgaag tattcgccaa
    30361 cctgatcatt gatttcctgc gaggtcgcca gcgacgtccc cagcggtttc tccatgacta
    30421 cgcgtgccgg tttagcattc agttttgcct cgccaagccc tttgcaaatt gcgccaaaag
    30481 tgctgggcgg catggcaaag tagttaatgg tgatacgatt tttttgatcc agcatcgcgc
    30541 cgagacggct gaatgcagca gtgtcattga catcgagatt acaaaaatcc agacgtgcac
    30601 tcagggtgtc ccataaacct tcatcaatgg tttctttcat gaaagtttcg agcgcctcgc
    30661 ggacaacttt ggtatatgcc gctttatccc agtcagcacg ccctacgccg ataatccggg
    30721 tgtccgggtt gagctgaccg gctttttcca gttgatacag ggaaggcagc aatttacgac
    30781 gcgcaaggtc gcctttcgcg ccgaaaatga ccaggtcaca ggcctgggct gtttgcgtta
    30841 ccgccatgtc attctcctta agttaactaa cccggtactt aagccagggt atacttgtaa
    30901 ttttcttacg gtgcactgta ctgcttttac gagcttgcga aaactgtaaa cgcttatcca
    30961 cccgtgcgat tacgggaaaa gcgcgcaaag tgcggcaaaa ctgataaaaa aatcatcgtt
    31021 ttccattggg taaaaatctg acactgatca tgttatgaaa aaaaataaca acttttttat
    31081 ctgcttttgt cattaacacg gcacacaggc gtaatatctg acaaaactgc atttcgattt
    31141 ctttcagtgc ggaaatcgtc attacccgtg agtctcttta catcatgaat atgctggaaa
    31201 aaatccagtc tcagctggaa catttgagca aatcagagcg caaagttgcc gaggtcattc
    31261 tggcttcgcc cgataacgcg atccattcga gtattgctgc tatggcactg gaagccaatg
    31321 ttagcgaacc gacggtgaat cgtttctgtc gcagcatgga cacgcgcggt tttcctgatt
    31381 ttaaacttca tctggcacag agtctggcga atggcactcc ctatgttaat cgcaatgtca
    31441 atgaagatga cagcgttaaa tcatacacag ggaaaatatt tgagtccgca atggcaacgc
    31501 ttgatcatgt ccgtcattca ctggataaat ctgccatcaa ccgcgccgtc gacttgctca
    31561 ctcaggcaaa aaaaatcgcc tttttcggat taggctcttc agccgccgtt gcccacgatg
    31621 cgatgaataa gttctttcgt tttaatgttc cggtggtgta ctccgatgat atcgtgctgc
    31681 aacgcatgag ttgtatgaat tgtagcgacg gagacgtggt ggtgctgatt tctcacactg
    31741 gaagaacaaa aaatctggtc gagctggcgc agctggcacg cgaaaacgac gccatggtga
    31801 ttgccctcac ctctgcgggt accccgctcg cccgggaagc aacgctggca attaccctcg
    31861 acgtaccgga agatactgac atttatatgc ccatggtttc tcgacttgca cagctgaccg
    31921 tgatagatgt gctggcgaca ggatttactt tgcgacgcgg tgcaaaattc agagataact
    31981 tgaagcgggt caaagaagcg ctgaaggaat cgcgttttga taagcagtta cttaatttaa
    32041 gtgacgatcg ctaaaaacga ctgtcactgt cctaatctta tacgacatcc gaatgagatt
    32101 aatttatcgc catcgcggcg ttatttcatt cggatttcat gttcaagcaa cacctggttg
    32161 tttcagtcaa cggagtatta catgtccaga aggcttcgca gaacaaaaat cgttaccacg
    32221 ttaggcccag caacagatcg cgataataat cttgaaaaag ttatcgcggc gggtgccaac
    32281 gttgtacgta tgaacttttc tcacggctcg cctgaagatc acaaaatgcg cgcggataaa
    32341 gttcgtgaga ttgccgcaaa actggggcgt catgtggcta ttctgggtga cctccagggg
    32401 cccaaaatcc gtgtatccac ctttaaagaa ggcaaagttt tcctcaatat tggggataaa
    32461 ttcctgctcg acgccaacct gggtaaaggt gaaggcgaca aagaaaaagt cggtatcgac
    32521 tacaaaggcc tgcctgctga cgtcgtgcct ggtgacatcc tgctgctgga cgatggtcgc
    32581 gtccagttaa aagtactgga agttcagggc atgaaagtgt tcaccgaagt caccgtcggt
    32641 ggtcccctct ccaacaataa aggtatcaac aaacttggcg gcggtttgtc ggctgaagcg
    32701 ctgaccgaaa aagacaaagc agacattaag actgcggcgt tgattggcgt agattacctg
    32761 gctgtctcct tcccacgctg tggcgaagat ctgaactatg cccgtcgcct ggcacgcgat
    32821 gcaggatgtg atgcgaaaat tgttgccaag gttgaacgtg cggaagccgt ttgcagccag
    32881 gatgcaatgg atgacatcat cctcgcctct gacgtggtaa tggttgcacg tggcgacctc
    32941 ggtgtggaaa ttggcgaccc ggaactggtc ggcattcaga aagcgttgat ccgtcgtgcg
    33001 cgtcagctaa accgagcggt aatcacggcg acccagatga tggagtcaat gattactaac
    33061 ccgatgccga cgcgtgcaga agtcatggac gtagcaaacg ccgttctgga tggtactgac
    33121 gctgtgatgc tgtctgcaga aactgccgct gggcagtatc cgtcagaaac cgttgcagcc
    33181 atggcgcgcg tttgcctggg tgcggaaaaa atcccgagca tcaacgtttc taaacaccgt
    33241 ctggacgttc agttcgacaa tgtggaagaa gctattgcca tgtcagcaat gtacgcagct
    33301 aaccacctga aaggcgttac ggcgatcatc accatgaccg aatcgggtcg taccgcgctg
    33361 atgacctccc gtatcagctc tggtctgcca attttcgcca tgtcgcgcca tgaacgtacg
    33421 ctgaacctga ctgctctcta tcgtggcgtt acgccggtgc actttgatag cgctaatgac
    33481 ggcgtagcag ctgccagcga agcggttaat ctgctgcgcg ataaaggtta cttgatgtct
    33541 ggtgacctgg tgattgtcac ccagggcgac gtgatgagta ccgtgggttc tactaatacc
    33601 acgcgtattt taacggtaga gtaagtacgt tgccggatgc ggcgaaaacg ccacatccgg
    33661 cctacagttc aatgatagtt caacagattt cgaatattct gaagcaaact tgaacttatc
    33721 atcaggcgaa ggcctctcct cgcgagaggc ttttttattt gatgggataa agatctttgc
    33781 gcttatacgg ctggatttcg cccggtttgc gagttttcag caattttagt atccaggtgt
    33841 attgttctgg tcgcggacca acaaaaatct cgacttcttc attcatccgc cgcgcaatcg
    33901 tatgatcatc cgcctctaac agatcatcca tcggtgggcg cacctgaatc gtcagacgat
    33961 gcgtcttgcc atcataaatc ggaaacagcg gtacaacgcg cgcacggcac actttcatca
    34021 aacgaccaat cgcgggcaac gtcgctttat aggtggcaaa gaaatccaca aattcgctgt
    34081 gctctgggcc atgatcctga tcgggtaaat aatatcccca gtacccctga cgtaccgact
    34141 ggatgaatgg tttaataccg tcatttctcg catgcagacg accgccaaag cgacgacgca
    34201 ccgtgttcca gacataatca aaaaccgggt tgccctgatt atggaacatc gctgccattt
    34261 tctgcccttg cgaggccatc agcatggcag gaatatcgac ggcccaaccg tgcggcacca
    34321 gaaagataac tttctcgtta ttacgccgca tctcttcgat gatctccagc ccttgccagt
    34381 caacgcgcgg ctgaattttc tccggcccgc gtattgccaa ctcagccatc attgccatcg
    34441 cttgcggcgc ggtggcaaac atctcatcaa caatcgcttc gcgttcagct tcactacgtt
    34501 ctggaaagca gagcgacaga ttgattaacg cacgacggcg tgagcttttt cccagtcgtc
    34561 cggcaaaacg tcccagccgt gccagaatgg gatcacggaa ctttggcggc gttaaagcga
    34621 tacccgccat cgctgctacg cccagccatg ctccccagta gcgcgggtgg cgaaaggatt
    34681 tatcaaactc aggaatgtat tcgctattat tttttttcgt ttccatgctt ttccagtttc
    34741 ggataaggca aaaatcaatc tggtgatagt gtagcggcgc aacttgcccc gcaccaaata
    34801 aaaaaagccg gtactgactg cgtaccggct gcgaatggat gttaattaat caaaccgtag
    34861 ctgcggcaca atctctttgg cctgcgccag gaattcgcga cgatcggagc cggtcagccc
    34921 ttcggtacgc ggcagttttg ccgtcagcgg gtttacggcc tgctggttta tccatacttc
    34981 atagtgcaga tgcggcccgg ttgaacgtcc ggtattaccg gaaagcgcga tacggtcgcc
    35041 acgtttcacc ttctgtcccg gtttcaccag aatcttgcgc aagtgcatat aacgcgtggt
    35101 gtagctgcga ccatgacgaa tagccacata ataacctgct gcgccactgc gtttggcaac
    35161 caccacttca ccgtcaccca ctgaaagcac tggcgtaccc tgcggcatgg cgaaatcaac
    35221 acctctgtgt ggtgcaacgc gaccggtcac cggattagta cgacgcgggt taaagttaga
    35281 cgagatacgg aactgtttcg ccgtcgggaa tcgcaagaat cctttcgcca gaccagtacc
    35341 gttacgatcg tagaatttgc catcttcagc gcggatagcg taataatctt taccttctga
    35401 acgcaaacgt acgcccagca gctggctttg ctcacgttta ccatcaagca tttctcgaga
    35461 cattaacacc gcaaattcat cgcctttttt cagtttgcgg aaatccattt gccactgcat
    35521 ggctttaatc actgcgctca cttcggcgct ggttaaaccg gcgtttctgg cgctggcaac
    35581 aaagcttccc ccgacggtac ctttcagcag attgttaacc cactctcctt gctgcatttc
    35641 gctggtcatt ttaaaaccgt tagcggcagt acggtcatag gttcgggttt cacgacgaga
    35701 cacttcccag gtgaggcgct gcagttcgcc gtccgcggtt aatgtccagg agagttgttg
    35761 accgattttc aggttacgca attctttgtc ggccgcagcc agttgggtga tatcacccat
    35821 atcaatacca tactgattga gaatgctgct tagcgtatcg ccagtggaaa caacatattc
    35881 atgcacgccc gcttcaccgg cgattttgtc atccagttcg tcctggggaa tggcttcatc
    35941 ttcttgtgca gcttgatcaa tcggctcact ggcttcaggt aagagcgaac gaatttcgtt
    36001 ctgttccagc tcaatggttt tgacaattgg cgtggcatca cggtgataaa cataaggccg
    36061 ccagacagcg acggccagag taagaacggt gagcgacccc aacataacgc ggtgtggtcg
    36121 cggtaaatta ttaaacgcca gggcgacaga gcgggctatc tgttgcacgt aatcacttcc
    36181 tcattaatct cctttcaggc agctcgcata ctggttggct aattgactca ggaattctga
    36241 atagcttgtt ttacccagtt tgatattcgt ccccagggga tccaacgttc ccatacgaac
    36301 ggatgtccct cgtgcgacgc tctcaacgac cgctggcctg aactgtggct cagcaaaaac
    36361 gcaggttgct ttttgctcaa ccaactgtgt tcttatttca tgtaaacgct gcgcgccagg
    36421 ttgaatctca gggttaacgg taaaatgacc aagcggtgtc agtccaaact gtttttcgaa
    36481 atagccgtaa gcatcgtgaa aaacgaaata acctttcccc ttgagcggcg cgagctcgtt
    36541 accaacctgc gtttcggttg aggctaattg tgcctcaaaa tccttcaggt tggcgtcaag
    36601 tttggctcga ctttgcggca taagttccac taattttcca tggattgcaa ccgctgtagc
    36661 ccgcgctatc tctggggaaa gccaaagatg catgttgaaa tcgccgtgat ggtgatcttc
    36721 gtcacttttt tccgcgtggt cgtgatcatc atcatcgccg tgaatacttt tcatcagtag
    36781 cggtttcaca tcttcaagct gcgcaatcgt tacctgcttc gctcctggta atttgcttac
    36841 cggtttttgc ataaacgctt ccatctccgg gccaacccaa acgactaagt ccgcgttctg
    36901 taagcgtttt acatccgatg ggcgcagtga ataatcatgt tctgaagcgc cgtcaggaag
    36961 taaaacctct gtttctgtta ccccatcagc aatggcagaa gcgatgaacc caacgggttt
    37021 aagcgaagcg acaacggcgg catctgcggc ctgtgttgca cctccccaga gagcggcgga
    37081 taatgctgcg aaaagaagcg tttttttatg taacataatg cgaccaataa tcgtaatgaa
    37141 tatgagaagt gtgatattat aacatttcat gactactgca agactaaaat taacatgaca
    37201 agtctggttt ccctggaaaa tgtctcggtt tcttttggcc aacgccgcgt cctctctgat
    37261 gtgtcgctgg aacttaaacc tggaaaaatt ttgactttac ttgggccaaa tggcgcaggt
    37321 aagtcgacac tggtacgggt agtgctcggg ctggtaacac ccgatgaagg ggttatcaag
    37381 cgcaacggaa aactgcgcat cggctatgta ccgcagaagc tgtatctcga caccacgttg
    37441 ccactgaccg taaaccgttt tttacgctta cgccctggta cacataaaga agatattttg
    37501 cctgcactga aacgtgtcca ggccgggcac ctgattaacg caccgatgca aaagctctct
    37561 ggtggcgaaa cgcagcgtgt actattagcg cgagcattgt taaatcgccc gcaattatta
    37621 gtgctggatg aacccactca aggcgtggat gtaaatggcc aggtggcgtt atatgacctt
    37681 attgaccaac tgcgtcgtga actggattgt ggcgttttaa tggtttctca cgatctgcat
    37741 ctggtgatgg caaaaaccga tgaagtgctg tgcctgaatc accacatttg ttgttccggc
    37801 acaccggaag ttgtttccct gcatccggag tttatttcaa tgtttggtcc tcgtggtgct
    37861 gaacaactgg gtatctatcg ccatcatcat aaccatcgtc acgatttaca gggacgaatt
    37921 gttttgcgtc ggggaaatga tcgctcatga ttgaattatt atttcccggt tggttagccg
    37981 ggatcatgct cgcctgtgcc gcgggtccgc tgggttcgtt tgtagtctgg cgtcgtatgt
    38041 cttatttcgg tgatacgctg gctcatgcct cattacttgg cgtcgcgttt ggtttgttgc
    38101 tggacgtgaa tccattctat gcggtgattg ccgttacgct gctgctggcg ggcggtctgg
    38161 tatggctgga gaagcgtcca cagctggcga tcgacacgtt attagggatt atggcgcaca
    38221 gtgccctgtc gctgggcctg gtggtcgtga gtctgatgtc taatattcgt gttgatttga
    38281 tggcttacct gttcggtgat ttgctggcag tgacgccaga agatctcatc tctattgcga
    38341 ttggcgtggt catcgtggtg gctattttgt tctggcaatg gcgcaatttg ctgtcaatga
    38401 cgataagccc ggatctggcg tttgttgatg gtgtgaaatt acagcgagtg aaattgttgt
    38461 tgatgctggt gacggcattg acgattggtg tagcgatgaa atttgtcggt gcgttgatta
    38521 ttacttcgtt gctgattatt cctgctgcta ctgcgcgtcg ctttgcccgc acgccggaac
    38581 agatggctgg tgtcgctgtt ttggtgggga tggtggcagt gactggcggt ttaacctttt
    38641 ccgcggttta cgatacgccg gcgggtccgt cggtggtgct atgtgcggca ctgttattta
    38701 ttctcagtat gatgaaaaag caggccagct aatctatcgc tgaacacatt tgtcggatgc
    38761 ggcgcgagcg ccttatccga cctacggttc ggtatctctg gtagtcctgg taagacgcga
    38821 acagcgtcgc atcaggcata ttgccagtgc cggatgcggc gcgagcgacc aatccgactt
    38881 acggcatttc tggcggcgtt atgccaaagt gattccacgc ccgcgtcgtc gccatacgcc
    38941 cacgcggtgt acgctgcaaa aagccttgct gaatcaaata aggttccagc acatcctcaa
    39001 tggtttcacg ttcttcgcca atggctgccg ccaggttatc cagacctaca ggtccaccaa
    39061 agaacttatc gattaccgcc agcaacaatt tgcggtccat ataatcgaaa ccttcagcat
    39121 cgacattcaa catatccagc gcctgagcag cgatatctgc cgagatggtg ccatcgtgct
    39181 tcacttcggc gaaatcacgc actcgacgca gcagacggtt ggcaatgcgc ggcgtaccgc
    39241 gagcgcgacg agcaacttcc agcgcgccgt catcactcat ctcaagcccc ataaagcgtg
    39301 cgctgcgact gacgatatat tgcagatccg gcacctgata aaactccaga cgttgcacaa
    39361 taccaaaacg gtcgcgcaac ggtgatgtca gcgaacctgc gcgcgtggtt gcaccaatca
    39421 gggtaaacgg cggcaaatca attttaatgg agcgtgccgc cggaccttca ccaatcatga
    39481 tatccagttg gtagtcttcc attgccgggt acagcacttc ttcaacaact ggcgatagac
    39541 ggtggatctc atcaataaac agcacgtcat gcggttcaag gttagtgagc atcgcagcca
    39601 aatcgcccgc cttttccagc accggaccag aagtcgtgcg taaattaacg cccatttcat
    39661 tggcgacaat gttggcaagc gtagttttac ccaaccccgg aggaccaaaa atcaacaaat
    39721 gatcgagggc atcgccgcgc agtttcgctg ctttgatgaa aatctccatc tgtgaacgaa
    39781 cctgcggctg accaacatac tcttccagta atttggggcg aatggcgcga tctgctacat
    39841 cttccggcaa agtggtaccg gcagaaatca gacggtctgc ttcaatcatc ctttacctca
    39901 taacgcggcg cgtagggctt cgcgaattaa agtttcactg ctggcgtcag ggcgagcgat
    39961 tttgctcacc atgcggcttg cttcttgtgg tttatagccc agcgccacca gcgcggcaac
    40021 cgcttcttgt tcagcatcgt cggtcgccgg gctggcagga gacgtgagta ccaggtcggc
    40081 ggctggcgta aagagatcgc catgcaaacc tttaaatcgg tctttcattt caacaatcaa
    40141 gcgttcggcg gtttttttgc caatacccgg cagtttcacc agtgccccca cttcttcacg
    40201 ctcaacggca ttaacgaact gctgcgctga cattccggag aggatcgcca gcgccaactt
    40261 cgggccgacg ccgttggttt tgatcaactc tttgaacaat gtgcgctctt gtttattgtt
    40321 aaaaccgtac agcagttgcg cgtcttcacg caccacaaag tgggtgaaaa cgatcgcttc
    40381 ctgacccgct tcagggagtt cataaaaaca ggtcatcggc atatgcactt catagcctac
    40441 gccgcccact tcaattaaca ccagcggggg ttgtttttca atgatgatgc ctctgagtct
    40501 gcctatcaca tgacgctcct gcgtaatgaa tcaaagataa tgctgtatga taaaaaaatg
    40561 ctggatagat atccagcgaa ggatgaagaa aacttgcgag gtgtctcgat gaactgaaaa
    40621 atggcacagt ataatttatt ctacaggtta tattggaagc aaatatttta atattacata
    40681 ttcagtgaag aaatgcgtaa taaaaatata cattgcgcct cctgaaaaaa taaatttttt
    40741 atgctattac gtatatttgt atctatttca atggaatgac aacgtgaata ttaattaccc
    40801 tgctgaatat gaaattggag atatcgtctt tacatgtata ggtgctgcct tatttggtca
    40861 aatatcagct gcatcaaatt gctggagtaa tcacgtcggg atcattatcg gtcataacgg
    40921 tgaagacttc ctggttgcag aaagccgggt tcccctttca accatcacca cgctatctcg
    40981 ttttattaaa cgttcgtcta atcaacgcta tgctataaag cgattagacg ctgggctgac
    41041 agaacgacaa aaacaacgaa ttgttgaaca ggttccctcc cggctacgca aactttacca
    41101 caccggtttt aaatacgaat cttcgcgcca gttctgttca aaatttgttt ttgatattta
    41161 taaagaagcg ctatgtattc cggtgggtga aatagagacg tttggagaat tgttaaatag
    41221 caatccgaat gcaaaactca ctttctggaa attctggttc ctgggttcta ttccgtggga
    41281 gcgtaaaacc gtcacgccag ccagtttgtg gcatcatccg ggtttggtgt tgattcatgc
    41341 ggagggagtg gaaacgcctc agccggaact gaccgaggcg gtataactta acgcagtcgc
    41401 cctctcgcca ggttcagccg cgattcgctc atctgcatcg cattctgact aacgtggcag
    41461 tgggtgatag caatcgccag cgcatcggcg gcatccgcct gtggattagc gggcagtttc
    41521 agcaaggtgc ggaccatatg ctgcacctgg cttttttcgg cactgccaat acctaccacc
    41581 gtttgcttta cctgacgtgc cgcgtattca aatactggca actcctgatt caccgccgcc
    41641 acaatcgcca cgccgcgcgc ctggcccagt ttcagggctg agtcagcgtt ctttgccata
    41701 aagacttgtt caatggcgaa ataatcaggc tggaactggg tgatgatttc cgtcacgccc
    41761 gcatagatga gtttcagacg agacggtaaa tcatccactt tggtgcggat gcatccgcta
    41821 cccaggtagg acagttgcct acctacctgg cggatgacgc cgtagccggt cacgcgcgaa
    41881 cccggatcaa tgccgagaat aatagccatc acgcgtctcc gttttgctgt ttagcaggcc
    41941 tcatcagaga gtcgctgcga cctcatcaga gatttcaccg ttatggtaaa cttcctgcac
    42001 gtcgtcgcaa tcttccagca tatcgatcag acgcatcagt ttcggtgcgg tttctgcatc
    42061 catatcagct ttggtagacg ggatcatgga aacttccgcg ctgtctgctt tcagacctgc
    42121 cgcttccaga gcgtcgcgca ctttacccat ttcttcccat gcagtgtaga catcaatcgc
    42181 gccgtcatca taggtcacaa cgtcttcagc acctgcttcc agtgctgctt ccatgatggt
    42241 gtcttcatcg cctttctcga aggagatcac gccttttttg ctgaacagat aggcaacgga
    42301 accatcagta ccgaggttac cgccacattt gctaaatgca tgacgcactt cagcaacggt
    42361 acggttgcgg ttgtcagaca gacattcaat catgattgcc gtgccgccag gaccgtaacc
    42421 ttcgtagatg atggtttcca tgtttgcatc atcatcaccg cccacaccac gtgcaattgc
    42481 gcggttcagt gtgtcacggg tcatgttgtt agacagtgct ttatccaccg ccgcacgcag
    42541 acgcgggtta gcgtccggat cgccaccgcc cagcttagcc gcggttacca gctcacgaat
    42601 gattttagtg aagattttac cgcgcttagc atcctgcgca gctttacgat gtctggtgtt
    42661 ggcccattta ctatgacctg ccataaaaat atctccagat agccctgcct gttcaggcag
    42721 cgttaattac aaactgttca atcgcctgcc ggttgctcca ggacttagtg agcgccgccg
    42781 cagcaggcgc atcaagccac ttgtaagcca gatgttcagt gaaaacgatc tgccgctcgt
    42841 gcggaagcgc aagacagaac catgattccg tattacgcgt cacgcccggc gcatagcgat
    42901 gacgtaaatg tgaaaaaatt tcaaactcta ccgtgcgctg acagtcaatt aaggtcagtt
    42961 gttcagcgac aacatcaatg gtgacctctt cctttacttc gcgcatggca gcttgcggcg
    43021 cggtttcacc ctcttccacg ctgccggtta ccgactgcca gaaatcggga tcgtcacgcc
    43081 gctgcaacat cagcacccgt ttcgtatctt gtgcgtagat gaccactaag atcgaaacgg
    43141 gacgcttata cactttatcc ttcacgctgc ctcttcgttg actgccttcg ctcatcccat
    43201 tcacatagtt atctatgctc atgggagttc actcagttgc cgcctcgatg caacgcgaat
    43261 gatttcgtgt atttgagtca tatcagttat tctcagcctt cttcacaacc tgaatgctca
    43321 gctcagccag tgcagtcggg ttagcaaagc tcggtgcttc agtcatcaga cacgctgccg
    43381 ccgtggtttt cgggaaggcg ataacgtcac ggatattgtc ggtgccggtc agcagcatgg
    43441 tcagacggtc aagaccgaat gccagacctg cgtgcggcgg agtaccgtat ttcagagcgt
    43501 cgagcaggaa gccgaatttc tcgcgctgtt cctcttcgtt gatacccaga ataccaaaca
    43561 ccgtctgctg catatcacca ttatggatac gtactgaacc accgcccact tcgtaaccat
    43621 tgatgaccat atcgtaagcg ttcgccaccg cattttccgg tgcagctttc agttctgcag
    43681 ccgtcatatc tttcggtgag gtgaacggat ggtgcattgc cgtcaggccg ccttcaccgt
    43741 cgtcttcaaa catcgggaag tcgataaccc acagcggtgc ccatttgctt tcgtcggtca
    43801 gaccaaggtc tttacccact ttcaggcgca gtgcacccat cgcgtcggca acaattttct
    43861 tgttgtcggc accgaagaaa atcatatcgc catcttgcgc ggcagtacga tccaggatgt
    43921 cttcgatgat ttctgcatta aggaacttcg ctaccgggct gttgatacct tccagacctt
    43981 tcgcgcgttc gttaactttg atgtaagcca gacctttcgc gccgtagatt ttaacgaagt
    44041 taccgtattc gtcgatctgc ttacgggtca gcgatgcgcc gcccggaacg cgcagagccg
    44101 ctacgcgacc tttcggatcg ttcgccggac ctgcaaatac agcaaactca acagatttca
    44161 gcagatcagc aacgtcagtc agttccatcg ggttacgcag atccggttta tcagaaccat
    44221 aacggcgttc tgcttccgca aaggtcatta ccgggaaatc gcccagatcc acacccttca
    44281 cttccagcca cagatgacgc accagcgctt ccatcacttc acgcacttgc ggcgcggtca
    44341 tgaaagaagt ttccacatcg atctgagtaa attcaggctg acggtcagca cgcaggtctt
    44401 cgtcacggaa gcatttaacg atctgatagt aacggtcaaa accggacatc atcagcagct
    44461 gtttgaacaa ctgcggggat tgcggcagtg cgtagaattt acctttgtgc acacgagaag
    44521 gcaccaggta gtcacgcgcg ccttccggcg tggctttggt cagcatcgga gtttcgatgt
    44581 cgaggaagcc gtggtcatcc ataaaacggc gcaccaggct ggtgatttta gcgcgggttt
    44641 tcaggcgctg agccatttcc ggacgacgca ggtcgaggta gcggtatttc agacgcgctt
    44701 cttcggtgtt gacgtggtta gagtcaagcg gcagaacatc tgcgcggttg atgatagtca
    44761 gcgaggacgc cagcacttcg atttcgccgg tcgccatatc gcggttaata tttttttcgt
    44821 cacgcgcacg tacggtgccc gtgacctgaa tgcagaactc attacgcagt tcagaggcca
    44881 gctttaacgc gtccgcacga tccggatcga aaaatacctg cacgatacct tcgcggtcgc
    44941 gcatatcgat gaagatcagg ctaccaagat cacgacgacg gttgacccaa ccacacagag
    45001 tcacctgctg ccccacgtgg gacaaacgga gctgtccaca atattctgta cgcatgagat
    45061 atcccttaac ttagctgccg gcggatgccc cctgctgcgc aggtgaccaa gtcgcagcgt
    45121 tagctgtatg tcacaactga atgaaaaaag gcggctatta tactggaaat tctgccgcac
    45181 cgtaagagcc tggcccgcgc tggaacgcct cgttaccact ttatatcggg cctgaaatca
    45241 gactctacgc cagtttgcta taaaggtgtt gcccgaactc ataaaaatta acaaaatttg
    45301 tcgttccgcc atcggctaat cgcattaagg tgtgaggcac gattttgttt tttcaggagt
    45361 cattatgctt gaacttaatg ctaaaaccac tgcgctggtg gtgatcgatt tacaagaagg
    45421 catcttacct tttgccggtg gtccacatac tgccgatgag gtagttaatc gcgccgggaa
    45481 gctggcggcg aaatttcgcg ccagcggtca gcccgtgttt ctggtgcgcg taggctggtc
    45541 tgccgattac gctgaagcat taaaacagcc ggtcgatgcg ccctcaccgg ctaaagtgtt
    45601 gcccgaaaat tggtggcaac atcctgctgc attaggtgca accgacagcg atatcgaaat
    45661 catcaaacgt caatggggtg cgttttacgg tacggatctg gagttgcaat tacgccgccg
    45721 aggtatcgat acaatagtgt tatgtgggat ctcgaccaat atcggtgttg aatccaccgc
    45781 ccgcaatgcc tgggaacttg gctttaatct ggtgattgcc gaagacgcct gtagtgccgc
    45841 cagcgccgag cagcacaata acagtatcaa ccatatctac ccgcgcatcg cccgtgtgcg
    45901 tagcgtggaa gagatcctca acgcgttatg atttacatcg gtctaccgca atggtcgcat
    45961 cctaaatggg tgcggttggg gatcaccagc cttgaagagt atgcccgcca ctttaactgc
    46021 gtggagggca acaccacgct ttacgccctg ccgaaacccg aggttgtcct gcgctggcgt
    46081 gagcagacca cagatgactt ccgcttctgt tttaagtttc cggcgaccat ttcgcatcag
    46141 gcagcattac ggcattgcga tgatttagtg actgaatttt tgacccgcat gtcaccgttg
    46201 gctccgcgca ttgggcaata ctggctgcaa ctgcctgcca cattcggccc acgggagctg
    46261 cctgcgcttt ggcattttct cgattctctt cctggcgaat ttaattatgg cgtggaagtc
    46321 cgccatccac agtttttcgc caaaggagaa gaggaacaaa cgcttaatcg cggtttacat
    46381 cagcgcggcg ttaatcgggt gattttagac agccgcccgg ttcatgcagc acgtccacac
    46441 agtgaagcta ttcgcgacgc tcaacgaaaa aaacctaaag ttccggtaca tgctgtactg
    46501 acggcgacaa atccgctgat ccgttttatc ggtagtgatg atatgacgca aaaccgggaa
    46561 ttatttcagg tctggttaca aaaattagcg cagtggcatc agaccactac gccttatctt
    46621 tttttacata cgccagacat tgcccaggca ccggaactgg tacataccct gtgggaagac
    46681 ttacgtaaaa cgcttccaga gatcggagca gttccggcta ttccacagca atcttctctt
    46741 ttctgaattt gccacctatc atagacaggt gccatcggcc attttaaagg gagtttgtat
    46801 ggtaagcgcg ctgtacgccg ttttaagtgc gttgttatta atgaagttct cttttgatgt
    46861 cgttcgcctg cgaatgcagt accgcgttgc ctatggcgac ggcggtttta gcgaactgca
    46921 aagcgctatt cgcattcatg gtaacgcggt ggaatatatt cccatcgcga ttgtgctgat
    46981 gctgtttatg gaaatgaatg gcgcagaaac ctggatggtg catatttgcg gcatcgtttt
    47041 gcttgctggt cgtctgatgc attattacgg ttttcatcac cgtctgttcc gctggcgacg
    47101 ttccggcatg agcgccacct ggtgtgcgct gttgctgatg gtgctggcga atctttggta
    47161 tatgccctgg gagttggttt tctccctgcg ttagcgcaca atacgccact ttctttttcc
    47221 cggattttta cgttatgtct caccgcgaca cgctattttc tgcccctatc gccagactgg
    47281 gcgactggac ctttgatgaa cgggtagctg aagtcttccc ggatatgatc cagcgttccg
    47341 tacccggcta ttccaatatt atttccatga ttggtatgtt agccgagcgc ttcgttcaac
    47401 ctggtacgca ggtttacgat ctgggttgtt ctctgggcgc ggcgacgctc tcggtgcgtc
    47461 gcaacattca tcatgataat tgcaaaatta ttgccatcga caactccccg gcgatgattg
    47521 aacgctgccg tcgtcatatt gacgcctata aagcccctac gccagtagac gtcattgaag
    47581 gtgatattcg cgatatcgcc attgaaaacg catcgatggt ggtgctgaat tttaccctgc
    47641 aattcctgga accttccgag cgccaggcgt tactggataa aatttatcaa gggctgaacc
    47701 ccggcggcgc gctggtgctt tcggaaaaat tcagtttcga agatgccaaa gttggtgaac
    47761 tgttgttcaa catgcaccac gactttaaac gtgccaacgg ttacagcgaa ctggagatca
    47821 gccagaagcg cagcatgctg gaaaacgtga tgctgaccga ttccgtggaa acccataaag
    47881 cacgcctgca taacgccggt tttgagcata gtgagctgtg gttccagtgc tttaactttg
    47941 gttcactggt ggcattaaaa gcagaggacg ctgcatgatc gactttggta acttttattc
    48001 tctgattgcc aaaaatcatc tttcacactg gctcgaaacg ctgcccgcgc agattgctaa
    48061 ctggcagcgc gagcagcagc acgggttgtt taagcagtgg tcaaatgcgg tggagtttct
    48121 acctgaaatt aaaccgtatc gtcttgattt attgcatagc gttacggcag aaagcgaaga
    48181 gccactgagc gcagggcaaa ttaaacgcat tgaaacgctg atgcgcaacc tgatgccgtg
    48241 gcgcaaaggg ccgttctcac tgtatggcgt caacatcgat accgaatggc gttccgactg
    48301 gaaatgggat cgtgttctgc cccatctttc tgatttaacc ggacgcacca ttctggatgt
    48361 cggctgcggc agcggttatc acatgtggcg catgattggc gcaggcgcgc acctcgcggt
    48421 ggggatcgac cctacgcaac tgtttctgtg ccagtttgaa gcggtgcgta aactactggg
    48481 taatgatcag cgcgcgcatt tgttaccgtt aggtattgaa caacttccgg cactgaaagc
    48541 ctttgatacc gtcttttcga tgggcgtgct ttaccatcgc cgttcaccgc tggagcatct
    48601 atggcagttg aaagatcaac tggtcaatga aggtgaactg gtgctggaaa cgctggttat
    48661 tgatggtgat gagaacacgg tgctggtacc aggcgatcgt tacgcgcaaa tgcgtaatgt
    48721 ctatttcatc ccttccgcgc tggcgctgaa aaactggctg aagaagtgtg gttttgtaga
    48781 tatccgcatt gcggatgtga gcgttaccac cacagaagag cagcgacgca ccgaatggat
    48841 ggttaccgaa tcgctggccg atttcctcga cccacatgat ccgggtaaaa cggtggaagg
    48901 ttatccggca cctaaacgcg cggtgctgat tgcgcgcaag ccgtaaaggt ctggtattac
    48961 tgccggatgc ggcgtgaacg ccttatccgg cctacaaaac cttgctaatt caatatattg
    49021 cagggactat gtaggcctga taagcatagc gcatcaggca gctttacgtt tgcataacct
    49081 cagcgcccgt ttccgggcgc tattcacgtc ttacgcctga acagctggct gatcaaacgc
    49141 cgttaacttc ggtgcattgc ccgtatattt ttcgataccc ggtagtgtat ttttcaagga
    49201 acactttatc gtgtttgcct tgtgtcatca gggtatgcgc aatccctaac atcagtgcca
    49261 cgtcggtgcc catattcggc gcgatccagg tggcattatc gtcaaagaat tcgatggttt
    49321 cggagcggat aggatcaatg gcaatcactg gtttgccaga ttttttcagc tgatggaagt
    49381 attccagccc ttgctcatcg gtactgctcc aggcaatttt taaggtattc agcgggttca
    49441 ttccccacag caccacaacc tggctgtttt ccagaatcag cggccaggag gtctgctgtt
    49501 catacacctc tacagaaccg accacatgcg gcatgatcac ctgtgctgcc ccggttgaat
    49561 aatcgccgct atgcccggaa taaccgcccg ccaggttcat ataacgttgc agtaaggttt
    49621 gcgctttatg caacacgcca gaagagcgcc agccgtaaga tccggcaaaa atggccgatg
    49681 gtccgttagc tttacgaata cgatcatgtt gctcatgaat cagttttaat gcctgttccc
    49741 agctcacctg tacataggta tcttcgccac gacctttcgc cggttgcagt ggattatcga
    49801 gatagctttt tctcaccatc ggatgctgaa tacgcgccgt ggtgtgtacc tgatccgccg
    49861 ccgtagactg taaggaattc ggtatggttt tcgccagcgc gcctgttgaa gaaacaatct
    49921 tgccgtcctt cacttctacg ttcatcgctc cccaacgtcc cgcggagagg attttaccgc
    49981 ccttctcttc tgcccatgcg gggagcggtg ctgccgatgt caccaccagc gctccagcgg
    50041 caataccgct gtgtttaata aattcacgtc ttgttaatgt cataacttcc tccctgatca
    50101 acgaggatca ctgtttctcg gtaatatctt tggcgttgta ctggaaatac cgcgttaaaa
    50161 tgtccagttc gttttcgctc atgctggttc gtgcccccat tcctttggca atggacggcc
    50221 acgcattgac ggtgtaatgg tcggcggcaa taggggcatg acaaccagcg caataggtat
    50281 cgtcaagttt ttcagcgtat tgccatagcg gtttacggtc cgctaatgcg ggatcggtaa
    50341 gcgcaccctg taaagacgcc tgacgccatt gattgccgta ttcgtcagcc tgccattccc
    50401 cgtttacagt gagcgccttg ataccttctt cacttaatgt ggctagcgcc agccgttgac
    50461 ctgccgccag gtagagcgtg ttttcactgc cctgcatttg ataaccctgc aacagaacga
    50521 tcggctgttt gccactggca tcaacgacgg tgagatcggt tccaggattc acggtagcca
    50581 gctcgcctat gtgagaagtt ttgaaaggat aaatatgtgc gccattagtc actgaagtag
    50641 cggcctgact ttccagctca tgcgccgcgt tgtcatccat ttttatttct ggcggaaaat
    50701 gggcaatgcc tttatgacaa tcgatacagg tttcgctgtc cttttgtgct ttgttatgca
    50761 ttttctgcgc agattcactt tgcgaggcaa tatccatggc atcaaaagaa tggcaactac
    50821 ggcacgttgc agagtcagtg gcttttaatt ctttccatac tgtttcggcc atttcctggc
    50881 gatgagcttc gaacttatcg tcactgtcta ttttgccgct aacaaattca tgataaatat
    50941 ctttagatgc ctttaattta gcaaataaat aatccatccc tgactttgga atatggcaat
    51001 cggcacattc cgcacgtatc cctttctggt tcgaaaagtg gacagttccc tgatattcct
    51061 caaaaggttt actcatcgag tggcaggaaa ggcaaaatgc tgtatccgac gttttatgta
    51121 aggctttttg cgccagcaat aacccgccgc caccaaccac aaccgctatc agcaaaaaca
    51181 ataacccaat gcgttttttc cctcgcatag attcctctaa ttaaattact ggacaccgaa
    51241 atcattgtat aattaaatat acaacgaatt aaccgcttgc ataattaggc acaacactgc
    51301 ctgaaacaat cgataaagaa tatgatttat tacaatgtaa tcattaattg ctaaggaata
    51361 acccagttgc tatttagaat atatatttat cagttttagt aatttaaatc ccataattaa
    51421 tgtgaatata tacaatattt ttagcacaac gctatgcgca ctgtcacccg ctcaacagat
    51481 cacggttatc gttcgttttt tatactgttc agggataaaa aaaggcccct gttgaaattg
    51541 caggggcctg gtacgagcaa gcatcatatt gggcgacatg atgcaacggt aaaaatcatt
    51601 tggcctgatg gcgttcaatg attcctttca tttcagcaac cgccgccccg tctacgatat
    51661 aacgcgaata ctcgtccgcg tgttcatctg atgacatgga caatccttga ttacgataac
    51721 gcatcggtga ggcttgccac gctcccgcgg agctatggac ttccagcact ccggcatcga
    51781 ggaagtggtg caggttttct gcacggactc ctgctccggc cataatgatt ggagcatcac
    51841 gatgggcaat aagttccata atttttgata aaccttgcag tgcgtctgat ttttgccctg
    51901 atgtcagtac ccgggcaatg cccaattccg caagattatt gagtgtatgt aaagggttag
    51961 cgcacatatc gaaggcgcga tgaaaagtca ctgccagcgg accggcagca gccattattt
    52021 tttccattcg tggcatatcg acattcccgt caacatcgag aacgcccgtc accagtccag
    52081 gaaaacctaa ttcgcggacc gtgcgcacat cctcaagaat ggcggcaaac tcaccgtcgc
    52141 tgtagcaaaa atcaccaccg cgtgggcgaa ttatcggatg cacagggatc gtcacccgct
    52201 ggcgcacgga tttcagtaca cccaacgacg gcgttaagcc cccctctttt ggggctgcgc
    52261 ataattcaac tctgtctgcg ccgttttgct gcgccgttag tgcacattcc atgctgtaac
    52321 agcaaatttc cagtaatgcc atttttactc cttaattacg ccgactgctc gctggcaacg
    52381 atctcttcaa tggaccacgg atgaaactta atagttgttt tgccatcggt gaccgccagc
    52441 gtcggattcg gtaatcgctc atgctcacct tttggcgaac tggttttcac tgagatcccc
    52501 ggtaggctga gtccttcatc agaaagcaat gccagcgcac gggcattcag cgtttctgga
    52561 tcacccggca gaacgatttc aatatgttcc caaccttcgt gtgggtaacg tttttccccg
    52621 ggccacggta gctccacaat agaaaactgc cagtgcgcaa cctgtaccgg ttcatgcaat
    52681 ttaaacagac aaatcggtct gccattgatc atattttctg acaaaagctc gccacactgt
    52741 tcaaacccgc gacgccagcg ttcagcagtg gcgttttgat ggcaacgcaa agaaatgtga
    52801 tcggcagtca gcggagtgat attcaacccc agacggcggg aaagttcatc taatgcgtgg
    52861 ataaatcgcg gtaaatccga tgcaatatcc tgcagctcgt cgatagattg ccagttcgcc
    52921 ataatcactc ttcgtctttc agtaaaagcg ttaatttacc ctgttgccct gtgccaacca
    52981 accgctgatt tcacgccgct tctgatgcaa tagtgaaaac ggcaatacgc cacgcgcacg
    53041 ttgctgacga aaacagccat ttgcagtata ctcccgccct aatttcttta actggtgcgg
    53101 gcaatttttg ctcgcttcat caatgtaagg tattccggtg aatattcagg ctcttctctc
    53161 agaaaaagtc cgtcaggcca tgattgcggc aggcgcgcct gcggattgcg aaccgcaggt
    53221 tcgtcagtca gcaaaagttc agttcggcga ctatcaggct aacggcatga tggcagttgc
    53281 taaaaaactg ggtatggcac cgcgacaatt agcagagcag gtgctgactc atctggatct
    53341 taacggtatc gccagcaaag ttgagatcgc cggtccaggc tttatcaaca ttttccttga
    53401 tccggcattc ctggctgaac atgttcagca ggcgctggcg tccgatcgtc tcggtgttgc
    53461 tacgccagaa aaacagacca ttgtggttga ctactctgcg ccaaacgtgg cgaaagagat
    53521 gcatgtcggt cacctgcgct ctaccattat tggtgacgca gcagtgcgta ctctggagtt
    53581 cctcggtcac aaagtgattc gcgcaaacca cgtcggcgac tggggcactc agttcggtat
    53641 gctgattgca tggctggaaa agcagcagca ggaaaacgcc ggtgaaatgg agctggctga
    53701 ccttgaaggt ttctaccgcg atgcgaaaaa gcattacgat gaagatgaag agttcgccga
    53761 gcgcgcacgt aactacgtgg taaaactgca aagcggtgac gaatatttcc gcgagatgtg
    53821 gcgcaaactg gtcgacatca ccatgacgca gaaccagatc acctacgatc gtctcaacgt
    53881 gacgctgacc cgtgatgacg tgatgggcga aagcctctac aacccgatgc tgccaggaat
    53941 tgtggcggat ctcaaagcca aaggtctggc agtagaaagc gaaggggcga ccgtcgtatt
    54001 ccttgatgag tttaaaaaca aggaaggcga accgatgggc gtgatcattc agaagaaaga
    54061 tggcggctat ctctacacca ccactgatat cgcctgtgcg aaatatcgtt atgaaacact
    54121 gcatgccgat cgcgtgctgt attacatcga ctcccgtcag catcaacacc tgatgcaggc
    54181 atgggcgatc gtccgtaaag caggctatgt accggaatcc gtaccgctgg aacaccacat
    54241 gttcggcatg atgctgggta aagacggcaa accgttcaaa acccgcgcgg gtggtacagt
    54301 gaaactggcc gatctgctgg atgaagccct ggaacgtgca cgccgtctgg tggcagaaaa
    54361 gaacccggat atgccagccg acgagctgga aaaactggct aacgcggttg gtattggtgc
    54421 ggtgaaatat gcggatctct ccaaaaaccg caccacggac tacatcttcg actgggacaa
    54481 catgctggcg tttgagggta ataccgcgcc atacatgcag tatgcataca cgcgtgtatt
    54541 gtccgtgttc cgtaaagcag aaattgacga agagcaactg gctgcagctc cggttatcat
    54601 ccgtgaagat cgtgaagcgc aactggcagc tcgcctgctg cagtttgaag aaaccctcac
    54661 cgtggttgcc cgtgaaggca cgccgcatgt aatgtgtgct tacctgtacg atctggccgg
    54721 tctgttctct ggcttctacg agcactgccc gatcctcagc gcagaaaacg aagaagtgcg
    54781 taacagccgt ctaaaactgg cacaactgac ggcgaagacg ctgaagctgg gtctggatac
    54841 gctgggtatt gagactgtag agcgtatgta atcgattttt cgtgagagtg aagcctgatc
    54901 agggttagcc gatcaggctt ttttattgcc atctaaatgt attctgaaaa tggacatgcc
    54961 attgttttct cactgttgga taagaggcca gaagcgtaat atccggcccc agggaaacga
    55021 taacggttga atttaaggaa taccgcagtg tttaaatttc ttgtattaac attaggcatt
    55081 atctcttgcc aggcttacgc agaagatacg gttatagtaa acgaccatga catttcagcc
    55141 atcaaagatt gttggcaaaa aaattcagat gatgatactg acgttaacgt gatcaaatca
    55201 tgcctgcgac aagaatacaa tctcgtcgat gcgcaattaa ataaagccta tggtgaagct
    55261 tatcgttata tagaacaagt gccacgcaca ggtgtaaaaa aacctgatac cgaacaactt
    55321 aacttgctta aaaaatcaca gcgagcctgg ctggatttta gggacaaaga atgtgaatta
    55381 atcctttcaa atgaggacgt tcaggattta agtgaccctt attctgaatc agaatggctc
    55441 tcatgtatga tcatacagac caatacgcga actcgccagt tgcagctata ccgtaactct
    55501 gaagattttt atccaagccc tttgacaaga ggataattca catctttttg gcatgttttg
    55561 ttgcaagcta ttcctgataa ataattgcaa caagacatcg agcctttttc actgagttat
    55621 taaacatact cgcgagcgcg taattttttt gtccttcagc gataattcac aatcacttca
    55681 ttacgttgta cctttagcgg tggaattaac cgcccaccgc ctggcacttc ccagataaat
    55741 cgcaacggtt ctgctgccgc tataccggaa aaggccacgg tggttccgct ctgcccctct
    55801 aattcgacac aacgagattg cgaacacaag cgaacccgca gtcctgaagg tgtcgggccg
    55861 ataagctgat aacgccacgc taccagcgtc atcaatcctg aagcaggttg tcgcgtagaa
    55921 agaggcgcag acgacatcga ctcaccgcga tgatttagcg taattcctac actacttgcc
    55981 tgccacatcc cctccccggc ggcttgcacc agcagcggaa acaataatat tgctaataag
    56041 gttctcatta tttgccgcca attgtcgccg tcatgcggat atgtcggtta tcagacagtt
    56101 ccagattcga caggaccact aactgcggca agctgcggcg caggaagcga gacaataatg
    56161 gtcgcagcgc gtggttcacc aacaatactg gcggcgcacc cagcatctcc tgacgggata
    56221 gcgcttcctg agtttgcgcc agtaaacgat ccgccagccc tggctccagt cctcccccgc
    56281 cctgcagcgc ctgtagtaac aaacgttcca gcggtgtatc gaggccaata acatggactt
    56341 catctttgcc aggaaaccac tgctgggtaa tcgcccgtcc caacgccacg cgcacgacgg
    56401 cggttaattc atgtggatcg ctttggatgg gcgcatgttc cgccagcgtt tcgagaatgg
    56461 tgcgcatatc gcgaatcggt actttttcat cgaggagatt ttgcagcact ttatgcagtg
    56521 tggtgagcgt gacgacgcca ggaacgagat cttccgtcag ctttggcatc tcctgggcga
    56581 cgcgatccaa cagctgttgc gcctcctgac gaccaaacag ctctgcggca tgctggctaa
    56641 tgaggtggtt aagatgcgtt gctaccaccg tgctggcctc aaccactgtg tacccctgaa
    56701 tctgcgcctg ttcttttagc gcactttcaa tccagatagc attcaggcca aatgccggat
    56761 cgacggtcgc ctcaccaggt aacgtcccgg cagcggttcc agggttaatc gccagccagc
    56821 gccccggata agcatcacca ctgccaatct ccacgccttt catcaaaatg cgatagcagg
    56881 caggttgcag atccatattg tcgcgaatgt gcaccactgg cggcagaaat cccatctcct
    56941 gggcaaattt cttgcggata ctgcgtatac ggcccaacaa ctcaccatcc tgctggaaat
    57001 cgaccatcgg gatcagtcga taacccactt ccattcccag agaatcttcc agttgtacat
    57061 cgttccacgt cgcttcgaca acggtattat tctctgccat ttttaccggt ttgggttcgg
    57121 caggcgcttt ttgttcgcgt ccgcgtatcc accaggccag cccgagcaat ccggcagtga
    57181 acagcaaaaa taccaggttc ggcattccag gcacctggcc gagtaaaccg agcacggcgg
    57241 cgcttaacaa cataacgctt gggttactga aaagctgatt caccatctgc tcgccaacat
    57301 cctgatcggt gctgacacgc gtaacgatga cccccgcggc ggtagaaatc accagcgccg
    57361 gaatttgtgc caccagaccg tcgccaatgg tcaatagcgt ataactttcc gccgcgtgtc
    57421 ccatgctcat gccatgttgc agcacgccga ccagcaaccc gccgacaacg ttaatgacca
    57481 tgatgaggat cccggcgatg gcatcgccgc gaacaaactt acttgccccg tccattgagc
    57541 cgtaaaaatc ggcttcctga gtcacttcgg agcggcgttt tttcgcctca tcttcaccaa
    57601 tcaatccggc gttaaggtcg gcgtcaatcg ccatctgctt acccggcata ccatcgagaa
    57661 caaagcgcgc acccacttct gcgatacgcc cggcaccttt ggtaatgacc ataaagttga
    57721 tgatcacgag aatgacaaac accacgatac cgatagcgaa attgccacca acgaggaagt
    57781 gaccgaacgc ttcgaccacc ttccctgccg ccgccgcgcc ggtatgccct tccattaaaa
    57841 tgatacgggt tgaagccacg ttaagtgcca gacgcaacag cgtggtaaac aacagaatgg
    57901 tcggaaacgc agcaaactca agcgtgcgct gggtaaacat cgccaccagc aacaccatga
    57961 tcgacaaggc aatattgaag gtaaacaaca ggtcgagtat gaatgcgggc agtggcagca
    58021 ccatcatcga caagatcaac aggatcaaaa tcggtccggc aaggatctgc cattgtgtcg
    58081 atttcaggtt tgcgggcagg cgcagcatcg cggccagatt actcatgggt cggtttctcg
    58141 ttaataaaat ccagggcttc cggcaccgga agatgagtag gttgtacagg gcgctgtcca
    58201 ccagccagac gccagcgttt cagttgccag acccaggcca gcacttccgc caccgcggcg
    58261 tacagttgac ccgggatttg ttgaccaatc tccgcatgtc gatacagcgc tcgcgccagc
    58321 ggcggcgctt caagcgtcgg gacgttattt tcagcgccaa tttcacgaat gcgcagcgcg
    58381 accagccctg cacctttagc gaccactttc ggtgcgctca ttttgttttc gtcatactgc
    58441 aacgctaccg aatagtgggt cgggttattg acaatgacat ccgctttcgg cacatcggcc
    58501 atcatccgac gccgtgcggc agctcgctgc atctgacgga tccgtccttt aacatggggg
    58561 tcgccttcgc tttgtttgaa ctcatcacga atatcctgcc gcgacattcg cagctttttc
    58621 aggtggctga agatttggaa aaagacgtca aatcccacca ttggaatgac accaagcacc
    58681 accagcagtg cgcatagccc taccaaatcc atcgcattac ccatggcggt aatcggagac
    58741 tcggccatta agcgcatcat ctgcggccag tgatgccaga gaaaaaaccc cgtcacgctg
    58801 ccaaccagga tggttttcaa aattgcttta agcaactccg cgccagtctg agccgagaac
    58861 atccgtttaa tgcccggtag cgggttgagt ttggaaaact tcggctgcaa ggatttgccg
    58921 ctaaatacca gccctcccag catgaccgga gaaatgagcg ccaccagtac cacgccgcta
    58981 atcagtggca gcagcgccag catggcttct ctgatcagca gaataatctg cccgaggatc
    59041 agattcgggt ctttgataat actgtgatca aaatgcagcc cagcggagag catgcccgac
    59101 aatcgacggg ccagcgacac accgccaaac cagataacac taacgcccac cagcaaaatc
    59161 agcagtgagg tcagttcacg ggaacgcggg atttgcccct cttcccgcgc tttttctagt
    59221 cggtgaggtg tgggggcttc tgttttgtcg tcgctctcgt cagacacgtc gccaatcctg
    59281 gaaagagtat taagcgtgaa tgatgccaga gcgcaaagcg ttcaatggtt tgagtaaggg
    59341 gcaaaacagg cgggatttag ggcttttgct gccacacatc aagcatagtg tgcgtttgtc
    59401 ggatgcggcg tcatcgcctt atcagaccgc ctgatatgac gtggtcacgc cacatcaggc
    59461 aatacaaatc aaaatccaag actatccaac aaatcgtcca cctgatcctg actggctacc
    59521 acaccggctt tgctggtatc gacctgaggt ccattaagca aactctggtt ttcacgtttt
    59581 ggacgcgact cctgttccgg gatgttttcc aacagcacca tcagcaactg gcgttcgatc
    59641 tcctgaatga catccatcat ccgcttaatg acctgcccgg tgagatcctg aaaatcctgc
    59701 gccatcatga tttccagcag ttgcgcgtta gtaaagctgg tatgcgcggg tacatctgcc
    59761 agaaattgtc gtgtatctgt taccagttca cgggcgtcgg caaggtcaat cggatcggca
    59821 aaccagtcat cccaacgttg ggttaacgct tttgctgatt tctccatttg atcctgatgc
    59881 ggttgtgacg cctcaacact gttcagcgcc cgctccgcag cctgggcggt catctgcaca
    59941 acatagtaca aacgatcgcg cgcatcgggg atggcttccg ccgcttcggc aatggcctga
    60001 tccagcccca gttcccgcaa actgtcgcgc agcatacgcg tcaggctgcc gatgcgcgca
    60061 atgatatcgc cagctgaatg ctcgtcagca ggtttgattg atggttgcat catagtcgca
    60121 tcctcacatg cccagtttct caaagatttt gttgagtttt tcctccagcg tcgcggcggt
    60181 aaatggcttc accacatagc cactggcccc cgcttgcgcc gcagcaatga tgttctcttt
    60241 cttcgcttct gcagtcacca ttaacactgg caatgccgac atcgcgccat ccgcacgaat
    60301 tgttttcagc aattccaggc catccatatt gggcatgttc cagtcggaga taacaaatcc
    60361 ataaccgcct gcctgcaact tattgagagc gtcgacgcca tcttccgctt cctcaacatt
    60421 attgaatccc agctctttca gcaggttacg cactatgcgt cgcatggtgg aaaagtcatc
    60481 cacaaccaaa aatttaagtt ctttatccgc catttcacac tcctgattta aatacgtatc
    60541 gcctgtccgg cactaatttt tgccaacatt tgctggctta cctggctaag atcgaccact
    60601 tcgcagacac cacccatatt gatggcctcg cgcggcatgc cgaacaccac gcaacttgct
    60661 tcgttttgcg caagggtcca tgcccccgcc tgacgcatcg ccaacattcc tgccgcgccg
    60721 tcgttgccca taccggtcag gatcacccca accgcattac gccccgcctg tttggcgaca
    60781 gaatggaaca acacatctac cgaaggccga tgacggttaa ccgccgggcc atcatgaatt
    60841 ttgatttggt aatttgcgcc actacgcgcc agctccatat gccgatcgcc cggcgcgata
    60901 taggcatgcc ccggcaaaac acgttctccg tcttcggctt ctttaacccc gatctgacaa
    60961 agcttattaa gtctgtcggc aaaagagcgg gtgaaaccag gcggcatatg ctgggtaatt
    61021 aacagtgccg ggctggaaag cggcaacggt tgcagtacgt gacgaattgc ctcagttcca
    61081 cccgttgaag caccaatcgc aatcagtttt tcagaactca acaacggccc tgccttcagc
    61141 gttgtcggtg ccgacaatgg cttatgtgct gcaaggctcg cctttgctgc tgtacgcacc
    61201 ttttcagcaa tcatttcgct atacgccagc attccttcgc gaatacccag ttgcggtttg
    61261 gtgacaaaat ctatcgcccc cagctccagc gcgcgcagcg tgacttctga ccctttgccg
    61321 gtcagggaag aaaccatcac tacgggcatt ggacgcaaac gcattaattt ttcgaggaaa
    61381 tccagtccgt ccatccgcgg catttcaaca tccagcgtca gcacatcggg attgaatttc
    61441 ttaatcaagt cacgcgcgac cagcggatca ggcgcggtcg ccaccatttc catgtcgcta
    61501 tggctgttga tgatttctgt catgatctgg cgcatcagtg ccgaatcatc gacagataac
    61561 accctgattt tgctcatcgt taatccttac ttagcgcata caccgtctga ccacgcagcg
    61621 tgaagcggcg ctcaaggtgg ctaaagtttt cagagtgacc cgcaaacagc aatccgtcgg
    61681 gtttaaggag cggaacaaag cggcgcaaaa tctcctgctg ggtattttga tcgaagtaga
    61741 tcatgacgtt acgacagaag atcgcatcaa acggccccgg cacggtgtac tgtttcgcca
    61801 gtagattcag cggggcaaaa tcaacatagt tcgccagctc ctgacgcacg cgtaccagcc
    61861 cttcatgcgg tcccgtccct cgcatgaaat accgttgcag ttgctgcggc gtcaggtttt
    61921 tcaactcttc atggcgataa ataccgcttc tggctttttc cagcactttg gtgtcgatat
    61981 cactggcaaa cactttccag cgtccgggcg cggtgcccaa tgtgtcagcc agcgtcatcg
    62041 caatgctgta cggctcttcg ccggtcgaag ccgccgcgct ccatacgcga tactcgccag
    62101 aacggcgacg tgcgtgatcc gcgagcagag ggaaatggtg tgcctcacgg aaaaatgccg
    62161 tcagattcgt ggtcagcgaa ttgataaacg cctgccactc accgctgtgc tgattagatt
    62221 ccagcaagtt cagataatga ccgaaatccg tcagtcccag cgaacgcaaa cgacgaacca
    62281 gtcggttgta aaccatgtcg cgtttatggt cagccagaac gatcccggct cgttgataga
    62341 tcaattgact tatccgccga aaatgcgcgt cggaaagcgc caggcgctcg gtcatctgta
    62401 acaataaaga cgtttgccca cagggcagag atgaagtcat agcgccttct caatcacttc
    62461 aggataccac tggcgcaatt tgtaactgca ccgactcatg tcgtgctact tcatgttctt
    62521 caaggggaaa taccgccaca cgcgacgaaa gatggtcggc ctgattcgcc agttgttccg
    62581 ttgccaccgc cgcttcttct accagcgagg cgttctgctg agtcacctga tccatctggc
    62641 tgacagcctg tgcaacctgc tcaatccccc gctgttgttc ttccgacgca gaggcaattt
    62701 ctcccataat gtcgttcacg cgggtcaccg aactgacaat atcgatcatg gtcgcggcgg
    62761 cgttattcac cagtttcgaa ccctgctgga cacgattgac tgactcttcg atcagccctt
    62821 tgatctcttt tgctgcctgc gcgctacggc tggcaagatt gcgcacttca cctgccacta
    62881 ccgcaaaacc acgcccctgc tctccggcgc gagccgcttc cactgccgca ttcagggcca
    62941 gaatattggt ctggaaagca attccgtcga taacgctgat aatgtcgcca attttttgcg
    63001 agctggtggc gatctcctgc atggtgtgag tcatggtact gacctgaaca ccgcccgcct
    63061 gcgccgttgt cgcggcattt tttgccagtt ccgacgcctg tcgtgcgtta tcggcgtttt
    63121 gccctaccgt ggcggttaat tgctccatac tggcggccgt ttgtgccagc gatgccgcct
    63181 gctgttcggt acgacttgag agatcgttat tgcctgcgac aatctccgcg ataccaatgt
    63241 gcatctcctg gcttccctta cgcacatcac ttaccgtccc acgcaaagcc tgctgcatgg
    63301 tcttcagact ggcaaaaatg gcggtgatct cattacgacc atataccgca atcggacgcg
    63361 ccagattacc cgcagcaatg ctgtcaaaat ggctaccgat aatggccagt ggttgaacaa
    63421 tcatcttgcg cgtccaccac agcgcactgc tgatgtagat cgccgcaaca ataatcatgc
    63481 tgataaacac cagtgccgaa atctgatagt tacgctggct ttgcgcactg gcggcttcca
    63541 gcacatggtt gatctccagc tgccaggcct caaagttaac gtcaaacgca ttctgtgatc
    63601 cctgcaccgg cgcagtgagg aaatccgaaa gttgattact ttcaagccag ctcgcctgat
    63661 gttcgagatc gttgtgccag cgggcaaaac ttttctccgt ctctttttgc aatgccctga
    63721 cgtgctcgtt gcccgcagtc atcgccataa aacttttaaa cagcgtggtg gattgcgtca
    63781 gactggcgcg cgccgtcgtc atcaacgttt taatgtcatc cgccggatag ctaagtgccg
    63841 tcagagtgcc cgctttgttc agcgcggtac tggcctgtaa cattaccgcc cgagtttgcg
    63901 ctaatgccgc acgttgctga ttgctctgct cgacctgatt cagtcgttgc aaatcgtcgc
    63961 gaaatgccca aaaagacatg ccgttactgc caatctgcaa aatcccgcag agaatcaaaa
    64021 ttaaaaacag cgtggtcgaa attcgaatac gattaaacat caacgctccc catcaggcgg
    64081 caatgaccgc gttagtaaat actcgtcaaa atgtttccca gtttggatct tgttcagcaa
    64141 ttcgcagtcg tggctgtgcc ggtggttgct cactggcagg acgggatggt gtttgcggtt
    64201 tattggtgag tgggctggct gccagacgga acgcggaaac cgcttgcgtt aaacgactcg
    64261 cctgttcttc cagcgcagcg gcggcggcag ctgattcctg caccagcgat gcgttctgtt
    64321 gcgtgacgcg atccatttcc gaaaccgcca atgcgacttg atcgatgcca cggctctgtt
    64381 catccgatgc cgatgcaatc tcgcccataa tgtcagtcac gcgagtgaca gcattgacga
    64441 tattgttcat tgtttccccg gcgctttcga ccagcaccga accggtatca acgcgtgaga
    64501 cggagtcttc aatgagggct ttgatctctt ttgccgcctg ggcgctgcga ctggcaagat
    64561 tacgcacttc acccgccacc acggcaaaac cacggccctg ttcacccgca cgcgcggctt
    64621 caaccgcggc attcagcgcg aggatattag tctggaaggc aataccgtcg ataacgctga
    64681 taatgtcggc aattttcttc gaactatcgg cgatctcatg catcgttttc actacgccat
    64741 ccaccacttt gccgccgtgc tgggcggtgt cggaggcact ttgcgccagt tgcgaggcct
    64801 ggcgggcgtt atcggcgttt tgcttcactg tcgcggtgag ctgctccatg ctggcggcag
    64861 tttcttccag cgcggatgcc tgctgttcag tacgggagga aagatcggtg ttgcccgccg
    64921 caatttcacg ggtaccggca tagatggcat ctgaaccttc gcggacatga gtgacggtgt
    64981 cagtcaaaga gcgttgcata tgtgaaacgc tctgcgccag gtcgcccatt tcactgcgcc
    65041 cgtcaatggt cagggtattc gccaggttac caccggcgat ttcgcgaatg tgagcaataa
    65101 tttttgccag cggagtaagc aacatacggc gaatgccgta ccacgccacc agcagaatca
    65161 ataccaccac cagcgcgata accgccagtt gccactgggc aaatcggtaa tcatctgcgt
    65221 tgtcagtgac gatatcgcga tacagttttt cactgctgag ggcgtactga gcaaacgctt
    65281 cgcccattgc attttgcatt ccctgggttg gctgagcgaa ataagctcca gtattgccat
    65341 aatctagata atcaatcagt tcagttaacg ctgtgtaata gtttttatat ttttcatcaa
    65401 tattacgact ggtagcgacc atttcaggta acggtgccat gcttttgaat tttttataat
    65461 gcgtcgctgc ctgcgccaat gttttcctgg cgctatcgag caattcaact ttggcgttac
    65521 tttgttgatt ggaggaatcc atcatcatcc gtaccgctga acgactcagg ttaatgcgcg
    65581 tttgcagcat taaatcccag gttgacgtca gctcgccctg ctgttcccgt aattgattgg
    65641 aaaccacaaa gctcttctgg ctatggtgaa gggaagaaaa aaacagactg ccggaaataa
    65701 gctgtaacag tgcgaatacc cccagcacca ttaccaacag cgtgactacg cggatacggt
    65761 taatcataag gcaccttcct gaaaacaagt tgatctcgtt atcggcaagg aggggggaaa
    65821 ctttattgct gatgccaccc gccgcgaaat tgaaataaaa aacccgatgc gcagatcatc
    65881 gggttcattt caattgagga aatcgggaga attacgccac ttctgacgcc gcgctatcta
    65941 acagcgccat ctcttcgctg ttcagcagtt tttcgatgtt caccagaatc aacatccggt
    66001 cgcccagtgc gcccagtcca gtgagatatt ctgttgaaag cgtcacggca aattccggtg
    66061 ccggacgaat ttgctccgcc gtcaatgaaa gcacgtctga gacgccgtca accacgatgc
    66121 cgaccacccg ctgtccgaga ttcaggacga taactaccgt gttgtcgtta tagtccacat
    66181 ccacctggct gaacttaatt cgtaagtcaa caatcggcac aataacgccg cgcagattcg
    66241 tgacgccttt gataaacgct ggcgtgttcg caatccgtgt tacctgatcg tagccacgga
    66301 tctcctgcac tttcaggata tcaataccgt actcttcatc accaagggta aataccagaa
    66361 attcctggcc tgacggctcg ctggccagct ttgttacatt cgtcataccg gtcatattgt
    66421 taccttttta ctcattcagg cggcggtgtt cgccatacgt tgttcgcggt ttatcgcctg
    66481 caaggcggag acatcaacaa tcagtgccac gctgccgtcg ccaagaatgg tcgcagcaga
    66541 aatgccgggg actttgcgat agttactttc aaggttttta accacaacct ggtgttgacc
    66601 aattaattga tccaccagca aggcgtagcg gcgaccgcca ctttgtaaga tcaccacaat
    66661 tccctgggtg gcttcggttt tcgcgcccgc gacgttgaac actttccaca gttcgacgat
    66721 gggcagatat tcaccccgca cttccagcac ccgctcgccg ccggccagtg gatggagatc
    66781 ggcttcacgg ggttgcagtg attccataac agcattcagc ggcagaatga aaacttcatc
    66841 cgcaacgcgt acggacatgc cgtcgaggat ggccagcgtc agcggcagta aaatgcggat
    66901 cgtagtgcca gtaccctgct tcgactggat ttcgacatga ccgcccatct cctggatatt
    66961 acgtttaacg acgtccatgc cgacgccgcg cccggagacg tcggtgacct gctctgccgt
    67021 ggagaagcca ggtgcaaata tcagcatcgc gacttcgtcg tcgctcatgt tttcgctgac
    67081 agtcaaacct tgcgaggccg cttttgccag aattcgctca cggtttagcc ccgccccatc
    67141 gtcggtcact tcaatgcaaa tgttgccgcc ctgatgttcg gcagacagaa ttaaatttcc
    67201 gacgctgttt ttacctgcgg cgagccgttt ttctggcagt tcaataccgt gatcgaggct
    67261 attgcgtacc aggtgggtca gcgggtcgat aatgcgttct atcaggcttt tgtcgagttc
    67321 agtagaactg cccaccagcg tcagttctac ctgcttgccg agttttcccg ccagatcacg
    67381 caccagccgg ggatagcgac taaaaacata ttccatcggc atcatgcgaa tcgacatcac
    67441 tgattcctgc aaatcacggg cgttacgttg taactgcccc atgctggtta tcaaatcacc
    67501 atgattaacc gggtccagtt cgctggaacg ctgggcaagc atggactggg tgataaccag
    67561 ctcgccgacg aggttaatta attgatcaac cttttctacc gctacacgga tgctggtgga
    67621 ttcattgctg cgcgtcgttt tttcccgctc cacgcggccg gttggcgctt gttcggctgc
    67681 cagtttaagc actggtgggg tggatatttt tggcgagact tctactgttt caaaggtaat
    67741 ctgatcggct tcaatcacaa aacagagtac cgctgtgatg tcatcttcgg cgatgtcgcc
    67801 cggtaatatt gccgagagcg aatccgcccc tttcaccacg tcagttaacg ttgtcagatg
    67861 tcccagttct tcttccagca ggtcgacttc cccggccttc aggcgcgaaa ggataattcg
    67921 tcgcggcgac tgactgcgac tctgctcatc ttgcggttca cttttggcaa ccacacttaa
    67981 tcgggtcact gcggatggcg tttcgccttt cgcttctaat gccagttgac gcaaggcctg
    68041 gcagatataa tcgaagctgg cggcatccgg ctcttgcgac tgtttataag cgtcgagctg
    68101 ttcttgcatg atgtccttcg tttccaaaaa cagattgata atgtcggtgt tgagttgcat
    68161 ctcacctcgt ctggcttcat cgagcaggtt ttccatcaga tgcgtggttt cctgcaaaac
    68221 gctgaagcca aaagttcctg cccctccttt gatcgagtgg gcagcccgaa agatggcatt
    68281 caattgttcg gcatctggcg cttccggctg caaaaccagc aaatgctgct ccatgtcagc
    68341 caacagttcg tccgcttcat caaaaaatgt ctgataaaaa tcgcttatat ccatgctcac
    68401 gctgtcacct cggttcggct gatggcattg tgggaacact gacctgtggt gcaacctcag
    68461 gtttttccag ggcgcttact ggctcattct ggctttcggc gttttcatgc aaaatggcct
    68521 gttcggcttg tttgttcagt accagcaggc tgatgcgacg gttgacggca tcatcaggtc
    68581 cgcgatcgct taagcgcatc gttgccgcca tgccgacgac acgtaacact ttgccgctat
    68641 ccaaccctcc gaccatcagt tcgcggcggg atgcattggc ccgatcggca gaaagctccc
    68701 agttgctata tcctttctca ccgctggcgt aggggaaatc atcggtatga cctgaaaggc
    68761 taatacggtt gggaataccg ttcagtacag gcgcaatggc gcgcagaatg tcgcgcatat
    68821 agggttcgac atcggcactg ccggttctaa acatcgggcg attctggcta tcgatgatct
    68881 gaatacgtag accttcctgg accagatcga ttttgagatg gggacgtaac gcccgcagtt
    68941 tcggatcgga ctctatcaac tggtcgagat caccccgcaa tttccgcaat cgactttgct
    69001 ccatgcgttt tttcagctct tcgatgttcg gctgcttatt cacttccccc tggctttggg
    69061 tgtaatcatc accaccgccg ggaattgggc tttcactatt agaaatgcga tcgccgcccg
    69121 taaccgcagt cgccagtgga gtccggaagt actccgcaat ctgaatcagc tcttttgggc
    69181 tggagatgga gatcagccac atcaccagaa aaaaggccat catcgcagtc ataaagtcgg
    69241 cataagcaat cttccacgat ccatgtgctg ccccgtggct tttggctttg cgtcgtttga
    69301 cgacaataat cggatgcgct tgattcttca tgcttcctcg gttgtcgtct gttgttgcgg
    69361 atttttcacc gcacgcacat gctcttccag ttcaataaac gacggacgtt cgctggaata
    69421 gagcgttttg cgaccaaact caacggcgat aggcggtgcg taaccgttca gattagaaag
    69481 cagagtgact ttgacgcact gcatcatttt gctggtttcg gcgcttttct gacgtaaaac
    69541 agtcgctaat ggggaaataa atccgtaagc caataaaatg ccgaggaaag tccccaccat
    69601 cgcatgtgcg ataagcgcac ccagctcggc ggcaggacga tcggctgaac ctaacgcgtg
    69661 aacgaccccc attacagccg caacaatacc aaacgccgga agtgagtccc cgaccagcgc
    69721 cagactgttc gccgggactt ctgcctcgct ttcgtgcgtc tcaatctctt catccatcag
    69781 ggcttcgatt tcgaaggtgt tcatgtgacc gctgataatc aggcgcagat aatcgacgat
    69841 aaaatcaagc atgacgctat ccgcgaggat gcgtgggtag ctggcgaaga tctcgctctc
    69901 acggggattt tcaatatcac gttccagcga aaacatcccc atctgccgcg attttgccat
    69961 caaccgataa agcagagcca gcagatccat atacattgct ttggtgtatt tggagcgacg
    70021 aaacagcaac ggcagcgcct tcagcgtgcc tttaatcgct ttgccattat tgccgacgat
    70081 aaacgaccca atccctgcac cggcaataat caccagttca gcgggttgat agagtgctcc
    70141 aaggcttcca ccggtcatca aataaccgcc gaaaactgta ccgagaacaa ccaggtaacc
    70201 taataagata agcacgacat catccttcca ctgttgacca tgacaggatg ttcagtcgtc
    70261 aggcgttaac gcgcgattgg ggcaaaaaaa agcagcggta cgtcgttacc gctgctggaa
    70321 tgttgcgcct caccgtatca gttaaacagc ctgtactctc tgttcatcca gcagttgtgg
    70381 gataatatcg gcaggattct gggaaagttt acgtcttttt actgccctgg atggcggttg
    70441 acataagctg caggcaaagc tgccaacagg ctggtgagcg tgggtaataa aattgccgcc
    70501 gcagcagttg cagctggaaa gttgcagtaa tccactttca acaaaccgca ccaatgtcca
    70561 ggcacgagtt aatgccagca gtggtccttc ttctgcttgt gggcactgtt caaggtataa
    70621 acggtaggct ttgatcaccg catcgacgcc attacacaaa ccggttttca gtaaaaactg
    70681 ccatgcatta cagaacatcg aagcatgaac gttttgttcc caggtcataa accagtcggt
    70741 tgagaatggc agcatgcctt tcggcggtgg gcttccgcgc agttctttat aaagttttat
    70801 caggcgtccg cgacttaact gtgtttcgct ttccagcatc tgcaaacgag cgcccagggt
    70861 gatcaattcc attgccagct gaatatcccg cgcttcctga acaatgcttt tttcactcat
    70921 gatcaggccc ttttcttgcg cagcgcttct tcaggctgat taacatcatt cagcaagcgt
    70981 gttgagagca tgatgccggt atgaatttgc tggagatcgt caacgcggga atcttgcgtc
    71041 aactgagtaa tcgtctggtg gctgtcaaaa cggaagtgac aaaccagctg attggtttct
    71101 gccagcttaa ccatttgcgg aagagtcagt gccgctaatg ttgtcgccat ttcttcattt
    71161 atgccgagac gaaacatagc ggacgctttg tcctgaacaa tcatacgctg tacaagtagt
    71221 aaatatgaca agttgatgtc ataaatgtgt ttcagcaact cggaggtatg cattattccc
    71281 acccagaata accaacttta tttttatgcg gtttcaccgc accctgtgat gtcgccggga
    71341 agccccggta aaaataatta gcattagaat agttgcgata agctgcaata agcagagcca
    71401 cctttttggt ttaataagtc cttacaaata gaagggggtc tttacactta tctaagattt
    71461 ttcctaaatc gacgcaactg tactcgtcac tacacgcaca tacaacgcag ggggctgcga
    71521 ttttcaataa tgtgtgatgc agatcacaca aaacactcaa ttacttaaca taaatgtata
    71581 agtcatactt ttgttttggg tgtatttcaa tctgttaaaa agtttttcgc tacgctagca
    71641 agcaaaaatg aaacaggaat aatcgaaatg ggatgttgcg cacagttaaa ataactcacc
    71701 gtaaataatc atctgctata aataatcact ttcatgcaat accagataag ctatttttaa
    71761 acagacactt accgcacaac aaactaatta aatacaaaga aaggcaacaa tcaacataat
    71821 gttaatgaaa tgttttacat atattaacc
//
LOCUS       DACAOP010000012        68823 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.012, whole genome shotgun sequence.
ACCESSION   DACAOP010000012 DACAOP010000000
VERSION     DACAOP010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 68823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68823
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.012"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(86..1216)
                     /gene="dnaJ"
                     /locus_tag="IT892_000895"
     CDS             complement(86..1216)
                     /gene="dnaJ"
                     /locus_tag="IT892_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAP3134135.1"
                     /translation="MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDQEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     gene            complement(1305..3221)
                     /gene="dnaK"
                     /locus_tag="IT892_000896"
     CDS             complement(1305..3221)
                     /gene="dnaK"
                     /locus_tag="IT892_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAP3134136.1"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     gene            3598..4002
                     /locus_tag="IT892_000897"
     CDS             3598..4002
                     /locus_tag="IT892_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2541 family protein"
                     /protein_id="HAP3134137.1"
                     /translation="MKSVFTISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLAL
                     KLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     gene            4028..4741
                     /gene="msyB"
                     /locus_tag="IT892_000898"
     CDS             4028..4741
                     /gene="msyB"
                     /locus_tag="IT892_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HAP3134138.1"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPEQHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKNMDEEHKQEFLHAVDARVNELEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVT
                     IPAVLQIACLRRMVSATQV"
     gene            4890..5456
                     /gene="satP"
                     /locus_tag="IT892_000899"
     CDS             4890..5456
                     /gene="satP"
                     /locus_tag="IT892_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HAP3134139.1"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     gene            complement(5491..6078)
                     /gene="mog"
                     /locus_tag="IT892_000900"
     CDS             complement(5491..6078)
                     /gene="mog"
                     /locus_tag="IT892_000900"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HAP3134140.1"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAAGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE"
     gene            complement(6193..7146)
                     /gene="tal"
                     /locus_tag="IT892_000901"
     CDS             complement(6193..7146)
                     /gene="tal"
                     /locus_tag="IT892_000901"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HAP3134141.1"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL"
     gene            7425..8855
                     /locus_tag="IT892_000902"
     CDS             7425..8855
                     /locus_tag="IT892_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HAP3134142.1"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDANGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
                     IQANAVARALSFSFDFPPLVTGIILAVFALLAITRGLHGVARLMQGFVPLMAIIWVLT
                     SLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAVAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRYPDIGRQLSPDAWDDVSQE"
     gene            8925..9701
                     /gene="yaaA"
                     /locus_tag="IT892_000903"
     CDS             8925..9701
                     /gene="yaaA"
                     /locus_tag="IT892_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HAP3134143.1"
                     /translation="MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPP
                     QISTLMRISDKLASINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDNFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR"
     gene            complement(9854..10150)
                     /locus_tag="IT892_000904"
     CDS             complement(9854..10150)
                     /locus_tag="IT892_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HAP3134144.1"
                     /translation="MKKMQSIVLALSLVLVAPMAAQAAEITLVPSVKLQIGDRDNRGY
                     YWDGGHWRDHGWWKQHYEWRGNRWHPHGPPPPPRHHKKAPHDHHGGHGPGKHHR"
     gene            complement(10364..11650)
                     /gene="thrC"
                     /locus_tag="IT892_000905"
     CDS             complement(10364..11650)
                     /gene="thrC"
                     /locus_tag="IT892_000905"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HAP3134145.1"
                     /translation="MKLYNLKDHSEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     gene            complement(11651..12583)
                     /gene="thrB"
                     /locus_tag="IT892_000906"
     CDS             complement(11651..12583)
                     /gene="thrB"
                     /locus_tag="IT892_000906"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HAP3134146.1"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETF
                     SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
                     QRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN"
     gene            complement(12585..15047)
                     /gene="thrA"
                     /locus_tag="IT892_000907"
     CDS             complement(12585..15047)
                     /gene="thrA"
                     /locus_tag="IT892_000907"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HAP3134147.1"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLTAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHLLRHAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEG
                     KVLRYVGNIDEDGACRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     gene            complement(15128..15193)
                     /gene="thrL"
                     /locus_tag="IT892_000908"
     CDS             complement(15128..15193)
                     /gene="thrL"
                     /locus_tag="IT892_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="HAP3134148.1"
                     /translation="MKRISTTITTTITITTGNGAG"
     gene            complement(15407..16093)
                     /locus_tag="IT892_000909"
     CDS             complement(15407..16093)
                     /locus_tag="IT892_000909"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HAP3134149.1"
                     /translation="MRITIILVAPARAENIGAAARAMKTMGFSELRIVDSQAHLEPAT
                     RWVAHGSGDIIDNIKVFPTLAESLHDVDFTVATTARSRAKYHYYATPVELVPLLEEKS
                     SWMSHAALVFGREDSGLTNEELALADVLTGVPMVADYPSLNLGQAVMVYCYQLATLIQ
                     QPAKSDTTADQHQLQALRERAMALLTTLAVADDIKLVDWLQQRLGLLEQRDTAMLHRL
                     LHDIEKNITK"
     gene            complement(16493..16633)
                     /locus_tag="IT892_000910"
     CDS             complement(16493..16633)
                     /locus_tag="IT892_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134150.1"
                     /translation="MTKVRNCVLDALSINVNNIISLVVGTFPQDPTVSKTADILTILT
                     AT"
     gene            16729..17445
                     /gene="arcA"
                     /locus_tag="IT892_000911"
     CDS             16729..17445
                     /gene="arcA"
                     /locus_tag="IT892_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003856501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator ArcA"
                     /protein_id="HAP3134151.1"
                     /translation="MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILS
                     EYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYIT
                     KPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
                     LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDT
                     PEIIATIHGEGYRFCGDLED"
     gene            complement(17504..18856)
                     /gene="creD"
                     /locus_tag="IT892_000912"
     CDS             complement(17504..18856)
                     /gene="creD"
                     /locus_tag="IT892_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein CreD"
                     /protein_id="HAP3134152.1"
                     /translation="MLKSPLFWKMTTLFGAVLLLLIPIMLIRQVIVERADYRSDVEDA
                     IRQSTSGPQKLVGPLIAIPVTELYTVQEEDKTVERKRSFIHFWLPESLMVDGNQNVEE
                     RKIGIYTGQVWHSDLTLKADFDVSRLSELDAPNITFGKPFIVISVGDARGIGVVKAPE
                     VNGTALTIEPGTGLEQGGQGVHIPLPEGDWRKQNLKLNMALNLSGTGDLSVVPAGRNS
                     EMTLTSNWPHPSFLGDFLPAKREVSESGFQAQWQSSWFANNLGERFASGNDTGWENFP
                     AFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQRLHPMQYLLVGLSLV
                     MFYLLLLALSEHTGFTVAWIIASLIGALMNGIYLQAVLKGWRNSMLFTLALLLLDGVM
                     WGLLNSADSALLLGTSVLVVALAGMMFVTRNIDWYAFSLPKMKASKEVTTDDELRIWK
                     "
     gene            complement(18914..20338)
                     /gene="creC"
                     /locus_tag="IT892_000913"
     CDS             complement(18914..20338)
                     /gene="creC"
                     /locus_tag="IT892_000913"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CreC"
                     /protein_id="HAP3134153.1"
                     /translation="MRIGMRLLLGYFLLVAVAAWFVLAIFVKEVKPGVRRATEGTLID
                     TATLLAELARPDLLSGDPTHGQLAQAFNQLQHRPFRANIGGINKVRNEYHVYMTDSQG
                     KVLFDSANKAVGQDYSRWNDVWLTLRGQYGARSTLQNPADPESSVMYVAAPIMDGSRL
                     IGVLSVGKPNAAMAPVIKRSERRILWASAILLGIALVIGAGMVWWINRSIARLTRYAD
                     SVTDNKPVPLPELGSSELRKLAQALESMRVKLEGKNYIEQYVYALTHELKSPLAAIRG
                     AAEILREGPPPEVVARFTDNILTQNARMQALVETLLRQARLENRQEVVLTVVDVAALF
                     RRVSEARTVQLAEKNITLHVMPTEVNVAAEPALLEQALGNLLDNAIDFTPESGRITLS
                     AEVDQEHVALKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSEVARLFN
                     GEVTLRNVQEGGVLASLRLHRHFT"
     gene            complement(20338..21027)
                     /gene="creB"
                     /locus_tag="IT892_000914"
     CDS             complement(20338..21027)
                     /gene="creB"
                     /locus_tag="IT892_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CreB"
                     /protein_id="HAP3134154.1"
                     /translation="MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKAR
                     QQAPDVMILDVGLPDISGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYV
                     AKPFSPREVCARVRTLLRRVKKFSSPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEF
                     LLLKTLLKSPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLRAKLRAINPDLSPINT
                     HRGMGYSLRGL"
     gene            complement(21040..21513)
                     /gene="creA"
                     /locus_tag="IT892_000915"
     CDS             complement(21040..21513)
                     /gene="creA"
                     /locus_tag="IT892_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CreA"
                     /protein_id="HAP3134155.1"
                     /translation="MKYKHLILSLSLIMLGPLAHAEEIGSVDTVFKMIGPDHKIVVEA
                     FDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAISCQQVGPIELSDRIKNGKAQGE
                     VVFKKRTSLVFKSLQVVRFYDAKRNALAYLAYSDKVVEGSPKNAISAVPVMPWRQ"
     gene            21724..22593
                     /gene="robA"
                     /locus_tag="IT892_000916"
     CDS             21724..22593
                     /gene="robA"
                     /locus_tag="IT892_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     RobA"
                     /protein_id="HAP3134156.1"
                     /translation="MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKD
                     VTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPAL
                     YRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR
                     YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVM
                     LQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRP
                     INLRCELLIPIRR"
     gene            complement(22590..23237)
                     /gene="gpmB"
                     /locus_tag="IT892_000917"
     CDS             complement(22590..23237)
                     /gene="gpmB"
                     /locus_tag="IT892_000917"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase GpmB"
                     /protein_id="HAP3134157.1"
                     /translation="MLQVYLVRHGETQWNAERRIQGQSNSPLTAKGEQQAMQVATRAK
                     ELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEEN
                     WRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
                     ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR"
     gene            23289..23801
                     /gene="yjjX"
                     /locus_tag="IT892_000918"
     CDS             23289..23801
                     /gene="yjjX"
                     /locus_tag="IT892_000918"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-canonical purine NTP phosphatase"
                     /protein_id="HAP3134158.1"
                     /translation="MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQ
                     PFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENTSQRGEARSA
                     TLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVIL
                     ALSPFHNAVY"
     gene            complement(23948..24274)
                     /gene="trpR"
                     /locus_tag="IT892_000919"
     CDS             complement(23948..24274)
                     /gene="trpR"
                     /locus_tag="IT892_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon repressor"
                     /protein_id="HAP3134159.1"
                     /translation="MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLT
                     PDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEE
                     VLLKSD"
     gene            complement(24364..26301)
                     /gene="sltY"
                     /locus_tag="IT892_000920"
     CDS             complement(24364..26301)
                     /gene="sltY"
                     /locus_tag="IT892_000920"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase"
                     /protein_id="HAP3134160.1"
                     /translation="MEKAKQVTWRLLAAGVCLLTVSSVARADSLDEQRSRYAQIKQAW
                     DNRQMDVVEQMMPGLKDYPLYPYLEYRQITDDLMNQPAVTVTNFVRANPTLPPARTLQ
                     SRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWNTGQSEEAWQGAKELWLTGK
                     SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPADYQTIASAI
                     ISLANNPNTVLTFARTTGATDFTRQMAAVAFASVARQDAENARLMIPSLAQAQQLNED
                     QIQELRDIVAWRLMGNDVTDEQAKWRDDAIMRSQSTSLIERRVRMALGTGDRRGLNTW
                     LARLPMEAKEKDEWRYWQADLLLERGREAEAKEILHQLMQQRGFYPMVAAQRIGEEYE
                     LKIDKAPQNVDSALTQGPEMARVRELMYWNLDNTARSEWANLVKSKSKTEQAQLARYA
                     FNNQWWDLSVQATIAGKLWDHLEERFPLAYNDLFKRYTSGKEIPQSYAMAIARQESAW
                     NPKVKSPVGASGLMQIMPGTATHTVKMFSIPGYSSPGQLLDPETNINIGTSYLQYVYQ
                     QFGNNRIFSSAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAY
                     YRYFMGDKPTLMSATEWGRRY"
     gene            26512..28179
                     /gene="ettA"
                     /locus_tag="IT892_000921"
     CDS             26512..28179
                     /gene="ettA"
                     /locus_tag="IT892_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HAP3134161.1"
                     /translation="MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAG
                     KSTLLRIMAGIDKDIEGEARPQPDIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALK
                     RLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKI
                     ANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHD
                     RYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWV
                     RQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYG
                     DRLLIDDLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVD
                     QFRDSMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGER
                     GRLHLAKLLQVGGNMLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIA
                     THILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYKRIAK"
     gene            complement(28487..29719)
                     /gene="nadR"
                     /locus_tag="IT892_000922"
     CDS             complement(28487..29719)
                     /gene="nadR"
                     /locus_tag="IT892_000922"
                     /EC_number="2.7.1.22"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463436.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional transcriptional
                     regulator/nicotinamide-nucleotide
                     adenylyltransferase/ribosylnicotinamide kinase NadR"
                     /protein_id="HAP3134162.1"
                     /translation="MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPS
                     AQKLEALHRFLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGFDD
                     TRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
                     IKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIDTVLVDPKRTFMSISGAQIRENPFRY
                     WEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDE
                     IALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALI
                     DEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEDDYD
                     SRFLRCVELVREMMGEQG"
     gene            complement(29740..31122)
                     /gene="radA"
                     /locus_tag="IT892_000923"
     CDS             complement(29740..31122)
                     /gene="radA"
                     /locus_tag="IT892_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAP3134163.1"
                     /translation="MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEVRLAASPT
                     VARNERLSGYAGSAGVAKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGG
                     NPGAGKSTLLLQTLCKLAQQMKTLYVTGEESLQQVAMRAHRLGLPTDNLNMLSETSIE
                     QICLIAEEEQPKLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMV
                     GHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQG
                     LREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLE
                     QNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQ
                     DLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKAPEGMQIFGVKKL
                     SDALSVFDDL"
     gene            complement(31171..32139)
                     /gene="serB"
                     /locus_tag="IT892_000924"
     CDS             complement(31171..32139)
                     /gene="serB"
                     /locus_tag="IT892_000924"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HAP3134164.1"
                     /translation="MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYG
                     RGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLAGSLTARATRLAHEAQLDVAPLG
                     KIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEMVAEVTERAMRGELDFTASLRS
                     RVATLKGADANILQQVRENLPLMPGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKL
                     RLTAVVANELEIMDGKFTGNVIGDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGAND
                     LPMIKAAGLGIAYHAKPKVNEKTEVTIRHADLMGVFCILSGSLNQK"
     gene            32245..32889
                     /locus_tag="IT892_000925"
     CDS             32245..32889
                     /locus_tag="IT892_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtjB family periplasmic protein"
                     /protein_id="HAP3134165.1"
                     /translation="MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQ
                     LEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQLTDESRILDAGVYDEQGDLIAR
                     SGESVEVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDN
                     TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEESEKKE"
     gene            32917..33933
                     /gene="lplA"
                     /locus_tag="IT892_000926"
     CDS             32917..33933
                     /gene="lplA"
                     /locus_tag="IT892_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase LplA"
                     /protein_id="HAP3134166.1"
                     /translation="MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTV
                     VIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIST
                     SIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLS
                     RLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITEAFFAHYGERVEA
                     EIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHI
                     TRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPDQEKELRELSTWIA
                     GAVR"
     gene            complement(34389..35108)
                     /gene="deoD"
                     /locus_tag="IT892_000927"
     CDS             complement(34389..35108)
                     /gene="deoD"
                     /locus_tag="IT892_000927"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP3134167.1"
                     /translation="MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVR
                     GMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLR
                     DVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLF
                     YSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAER
                     QTTFNDMIKIALESVLLGDKE"
     gene            complement(35188..36411)
                     /gene="deoB"
                     /locus_tag="IT892_000928"
     CDS             complement(35188..36411)
                     /gene="deoB"
                     /locus_tag="IT892_000928"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAP3134168.1"
                     /translation="MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEAD
                     NGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGH
                     WEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEH
                     MKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIG
                     DKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKAT
                     GLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMS
                     LLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLA
                     KYFGTSDMEYGKAMF"
     gene            complement(36463..37785)
                     /gene="deoA"
                     /locus_tag="IT892_000929"
     CDS             complement(36463..37785)
                     /gene="deoA"
                     /locus_tag="IT892_000929"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313368.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HAP3134169.1"
                     /translation="MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAM
                     TIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMV
                     AACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL
                     APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSE
                     ALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVT
                     MALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYL
                     PTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQ
                     VDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE"
     gene            complement(37912..38691)
                     /gene="deoC"
                     /locus_tag="IT892_000930"
     CDS             complement(37912..38691)
                     /gene="deoC"
                     /locus_tag="IT892_000930"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005097947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAP3134170.1"
                     /translation="MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTA
                     AICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVD
                     VVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIK
                     AGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAI
                     ADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY"
     gene            38949..40499
                     /locus_tag="IT892_000931"
     CDS             38949..40499
                     /locus_tag="IT892_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HAP3134171.1"
                     /translation="MPTSHENALQQRCQQIVTSPVLSPEQKRHFLALEAENNLPYPQL
                     PAEARRALDEGVICDMFEGHAPYKPRYVLPDYARFLANGSEWLELEGAKDLDDALSLL
                     TILYHHVPSVTSMPVYLGQLDALLQPYVRILTQDEIDVRIKRFWRYLDRTLPDAFMHA
                     NIGPSDSPITRAILRADAELKQVSPNLTFIYDPEITPDDLLLEVAKNICECSKPHIAN
                     GPVHDKIFTKGGYGIVSCYNSLPLAGGGSTLVRLNLKAIAERSESLDDFFTRTLPHYC
                     QQQIAIIDARCEFLYQQSHFFENSFLVKEGLINPERFVPMFGMYGLAEAVNLLCEKEG
                     IAARYGKEAAANEVGYRISAQLAEFVANTPVKYGWQKRAMLHAQSGISSDIGTTPGAR
                     LPYGDEPDPITHLQTVAPHHAYYYSGISDILTLDETIKRNPQALVQLCLGAFKAGMRE
                     FTANVSGNDLVRVTGYMVRLSDLEKYRAEGSRTNTTWLGEEAARNTRILERQPRVISH
                     EQQMRFSQ"
     gene            40471..41334
                     /gene="yjjW"
                     /locus_tag="IT892_000932"
     CDS             40471..41334
                     /gene="yjjW"
                     /locus_tag="IT892_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HAP3134172.1"
                     /translation="MNSRCALVSKIIPFSCVDGPGSRLALFLQGCNLRCKNCHNPWTM
                     GRCNHCGECVPQCPHQALQIVDGKVVWNAAVCEQCDTCLKRCPQHATPMAQSMSVDEV
                     LSHVRKAVLFIEGITVSGGEATTQLPFVVALFTAIKNDPQLRHLTCLVDSNGMLSETG
                     WEKLLPVCDGAMLDLKAWGSECHQQLTGRDNQQIKRSICLLAERGKLAELRLLVIPGQ
                     VDYLQHIEELAAFIKGLGDVPVRLNAFHAHGVYGEAQSWASATPEDVEPLADALKVRG
                     VGRLIFPALYL"
     gene            complement(41851..42633)
                     /locus_tag="IT892_000933"
     CDS             complement(41851..42633)
                     /locus_tag="IT892_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP3134173.1"
                     /translation="MICRFIDTHCHFDFPPFSGDEEASLQRAAQAGVGKIIVPATEAE
                     NFARVQALAEKYQPLYAALGLHPGMLEKHSDVSLDQLQQALERRPAKVVAVGEIGLDL
                     FGDDPQFERQQWLLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRHDLPRAGVVHGFS
                     GSQQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASLLLETDAPDMPLNGFQG
                     QPNRPEQAVRVFDVLCELRPEPEDEIAEVLLNNTYALFSVSG"
     gene            complement(42630..43703)
                     /locus_tag="IT892_000934"
     CDS             complement(42630..43703)
                     /locus_tag="IT892_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin family protein"
                     /protein_id="HAP3134174.1"
                     /translation="MGQRIPVTLGNIAPLSLRPFQPGRIALVCEGGGQRGIFTAGVLD
                     EFMRAQFNPFDLYLGTSAGAQNLSAFICNQPGYARKVIMRYTTKREFFDPLRFVRGGN
                     LIDLDWLVEATASQMPLQMDTAARLFDSGKSFYMCACRQDDYAPNYFLPTKQNWLDVI
                     RASSAIPGFYRSGVSLEGINYLDGGISDAIPVKEAARQGAKTLVVIRTVPSQMYYTPQ
                     WFKRMERWLGDSSLQPLVNLVQHHETSYRDIQQFIEKPPGKLRIFEIYPPKPLHSIAL
                     GSRVPALREDYKLGRLCGRYFLATVGKLLTEKAPLTRHLVPVVTPESIVIPPAPVAND
                     TLVAEVSDAPQANDPTFNNEDLA"
     gene            complement(43825..43986)
                     /locus_tag="IT892_000935"
     CDS             complement(43825..43986)
                     /locus_tag="IT892_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HAP3134175.1"
                     /translation="MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLV
                     SLFMGRKRP"
     gene            complement(44113..44718)
                     /gene="osmY"
                     /locus_tag="IT892_000936"
     CDS             complement(44113..44718)
                     /gene="osmY"
                     /locus_tag="IT892_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone OsmY"
                     /protein_id="HAP3134176.1"
                     /translation="MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVD
                     SSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVKTDQKVVTLSGFVESQAQAEEA
                     VKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRHVKVE
                     TTDGVVQLSGTVDSQAQSDRAESIAKAVDGVKSVKNDLKTK"
     gene            complement(45111..46700)
                     /gene="prfC"
                     /locus_tag="IT892_000937"
     CDS             complement(45111..46700)
                     /gene="prfC"
                     /locus_tag="IT892_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAP3134177.1"
                     /translation="MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAG
                     TVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRT
                     LTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVEN
                     ELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAA
                     VGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWA
                     PAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQV
                     RTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPN
                     FAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVV
                     SRLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSM
                     VNLRLAQERYPDVQFHQTREH"
     gene            complement(46791..47468)
                     /gene="yjjG"
                     /locus_tag="IT892_000938"
     CDS             complement(46791..47468)
                     /gene="yjjG"
                     /locus_tag="IT892_000938"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HAP3134178.1"
                     /translation="MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQA
                     VNKPLWVDYQNGAITSLQLQHGRFESWAERLNVEPGKLNEAFINAMAEICTPLPGAVS
                     LLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYAL
                     EQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHHREQPEGIAPTWTVSSLHEL
                     EQLLCKH"
     gene            complement(47483..47929)
                     /gene="rimI"
                     /locus_tag="IT892_000939"
     CDS             complement(47483..47929)
                     /gene="rimI"
                     /locus_tag="IT892_000939"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP3134179.1"
                     /translation="MNTISSLETTDLPAAYHIEQRAHAFPWSEKTFASNQGERYLNFQ
                     LTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWL
                     EVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM"
     gene            complement(47898..48311)
                     /gene="holD"
                     /locus_tag="IT892_000940"
     CDS             complement(47898..48311)
                     /gene="holD"
                     /locus_tag="IT892_000940"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit psi"
                     /protein_id="HAP3134180.1"
                     /translation="MTSRRDWQLQQLGITQWSLRRPGALQGEIAIAIPAHVRLVMVAN
                     DLPALTDPLVSDVLRALTVSPDQVLQLTPEKIAMLPQGSRCNSWRLGTDEPLSLEGAQ
                     VASPALTELRANPTARAALWQQICTYEHDFFPRND"
     gene            48414..49445
                     /gene="rsmC"
                     /locus_tag="IT892_000941"
     CDS             48414..49445
                     /gene="rsmC"
                     /locus_tag="IT892_000941"
                     /EC_number="2.1.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1207)-N(2))-methyltransferase
                     RsmC"
                     /protein_id="HAP3134181.1"
                     /translation="MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRA
                     HTQQFHHWQVLSRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLL
                     PVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWG
                     EYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHS
                     PKIRLTLCDVSAPAVEASRATLAANGVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQ
                     TSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRA
                     IMTRQAKKG"
     gene            49746..49832
                     /locus_tag="IT892_000942"
     tRNA            49746..49832
                     /locus_tag="IT892_000942"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49780..49782,aa:Leu,seq:cag)
     gene            complement(49871..50107)
                     /locus_tag="IT892_000943"
     CDS             complement(49871..50107)
                     /locus_tag="IT892_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313355.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1435 domain-containing protein"
                     /protein_id="HAP3134182.1"
                     /translation="MLQRTLGSGWGVLLPGLLIAGLMYADLSPDQWRIVILMGLILTP
                     VMLYHKQLRHYILLPSCLALSAGIMLMLMNLNQG"
     gene            50248..51036
                     /gene="fhuF"
                     /locus_tag="IT892_000944"
     CDS             50248..51036
                     /gene="fhuF"
                     /locus_tag="IT892_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-iron reductase FhuF"
                     /protein_id="HAP3134183.1"
                     /translation="MAYRSAPLYEDIIWRTHLQPQDAGLAQAVRATIAEHREHLLEFI
                     RLDEPAPLNAMTLAQWSSPNALSSLLAVYSDHIYRNQPTMIRENKPLISLWAQWYIGL
                     MVPPLMLALLTQEKALDVSPEHFHAEFHETGRAACFWVDVCEDKNATPHSPQQRMETL
                     ISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHAIFFEK
                     TLTNGEDNPLWRTVVLRDGLLVRRTCCQRYRLPDVQQCGDCTLK"
     gene            complement(51074..51751)
                     /gene="bglJ"
                     /locus_tag="IT892_000945"
     CDS             complement(51074..51751)
                     /gene="bglJ"
                     /locus_tag="IT892_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418786.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator BglJ"
                     /protein_id="HAP3134184.1"
                     /translation="MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGTPYKLHTYTSQ
                     ESFQDAISRISFAAVIFSFSAMRSERREGLSCLTELAIKFPRTRRLVIADDDIEARLI
                     GSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREI
                     LRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCEA
                     SNVLHPY"
     gene            complement(51709..52434)
                     /locus_tag="IT892_000946"
     CDS             complement(51709..52434)
                     /locus_tag="IT892_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP3134185.1"
                     /translation="MLPGCCKNGIVISKIPVMQAGLKEVMRTHFPEYEIISSASAEDL
                     TLLQLRRSGLVIADLAGESEDPRSVCEHYYSLISQYREIHWVFMVSRSWYSQAVELLM
                     CPTATLLSDVEPIENLVKTVRSGNTHAERISAMLTSPAMTETHDFSYRSVILTLSERK
                     VLRLLGKGWGINQIASLLKKSNKTISAQKNSAMRRLAIHSNAEMYAWINSAQGARELN
                     LPSVYGDAAEWNTAELRREMSHS"
     gene            53053..53823
                     /locus_tag="IT892_000947"
     CDS             53053..53823
                     /locus_tag="IT892_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HAP3134186.1"
                     /translation="MQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMD
                     SVESSISSNAIVLTTIKDGQCLTSTRKNHDRGINMHVVTEVQHIVILAEHHLLDYKGV
                     EKRFSQIQPLRYPRWLVALMVGLSCACFCKLNKGGWDGAVITFFASTAAMYIRQLLAQ
                     RHLHPQINFCLTAFAATTISGLLLQLPTFSNTPTIAMAASVLLLVPGFPLINAVADMF
                     KGHINTGLARWAIASLLTLATCVGVVMALTIWGLRGWV"
     gene            53814..54287
                     /locus_tag="IT892_000948"
     CDS             53814..54287
                     /locus_tag="IT892_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAP3134187.1"
                     /translation="MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAI
                     GHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISA
                     YTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV"
     gene            54394..54933
                     /gene="dnaT"
                     /locus_tag="IT892_000949"
     CDS             54394..54933
                     /gene="dnaT"
                     /locus_tag="IT892_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaT"
                     /protein_id="HAP3134188.1"
                     /translation="MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYA
                     VTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFI
                     RLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPK
                     RDVNTVSEPDSQIPPGFRG"
     gene            54936..55673
                     /gene="dnaC"
                     /locus_tag="IT892_000950"
     CDS             54936..55673
                     /gene="dnaC"
                     /locus_tag="IT892_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001731874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HAP3134189.1"
                     /translation="MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAAL
                     ERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIASF
                     IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDL
                     SNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVM
                     DRMRLGNSLWVIFNWDSYRSRVTGKEY"
     gene            55722..56216
                     /locus_tag="IT892_000951"
     CDS             55722..56216
                     /locus_tag="IT892_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2501 domain-containing protein"
                     /protein_id="HAP3134190.1"
                     /translation="MMKTVKHLLCCAIAASALISTGVHAASWKDALSSAASELGNQNS
                     TTQEGGWSLASLTNLLSSGNQALSADNMNNAAGILQYCAKQKLASVTDAENIKNQVLE
                     KLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGL
                     NFIS"
     gene            56470..58761
                     /gene="opgB"
                     /locus_tag="IT892_000952"
     CDS             56470..58761
                     /gene="opgB"
                     /locus_tag="IT892_000952"
                     /EC_number="2.7.8.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase"
                     /protein_id="HAP3134191.1"
                     /translation="MSELLSFALFLASVLIYAWKAGRNTWWFAAMLTVLGLFVVLNIT
                     LFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRR
                     HHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDP
                     KLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVAS
                     QCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKS
                     HGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVD
                     THHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIAAFINKIKASPWFKDTVIVVS
                     SDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNY
                     LGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGS
                     HFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELA
                     LSTDWCVSQGQLGGQQIVQHVDKTTWQGKTAFKDTVIDMARYKGNVDTLKIVDNDIRY
                     KADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITA
                     KAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGN
                     ILGHSPRKLGIGMVEIKVVEREG"
     gene            complement(58901..59923)
                     /locus_tag="IT892_000953"
     CDS             complement(58901..59923)
                     /locus_tag="IT892_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418778.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP3134192.1"
                     /translation="MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDI
                     HAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGR
                     TNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
                     APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARRDHVATRLELPLLDPSAEDF
                     DAQLRAQFGGSLAQKVIDATGNQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHK
                     KETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYPFATLAETYERDVINNRELI
                     KGVITF"
     gene            60062..60976
                     /locus_tag="IT892_000954"
     CDS             60062..60976
                     /locus_tag="IT892_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313344.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP3134193.1"
                     /translation="MSRSQNLRHNVINQVIDDMVRGHIPSPLPSQSALAEMYNISRTT
                     VRHILSHLRECGVLTQVGNDYVIARKPDHDDGFACTTASMSEQNKVFEQAFFTMINQR
                     QLRPGETFSELQLARAAGVSPVVVREYLLKFGRYNLIQSEKRGQWSMKQFDQSYAEQL
                     FELREMLETHSLQHFLNLPDHDPRWLQAKTMLERHRLLRDNIGNSFRMFSQLDRDFHS
                     LLLSAADNIFFDQSLEIISVIFHFHYQWDESDLKQRNIIAVDEHMTILSALICRSDLD
                     ATLALRNHLNSAKQSMIRSINENTRYAH"
     gene            61190..62551
                     /locus_tag="IT892_000955"
     CDS             61190..62551
                     /locus_tag="IT892_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3134194.1"
                     /translation="MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAM
                     LLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLD
                     RKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
                     IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYR
                     NREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLY
                     LAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKIC
                     IIAGMFCSAAFTLVVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASV
                     GSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDP
                     RKD"
     gene            complement(62600..64264)
                     /gene="tsr"
                     /locus_tag="IT892_000956"
     CDS             complement(62600..64264)
                     /gene="tsr"
                     /locus_tag="IT892_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HAP3134195.1"
                     /translation="MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQ
                     TIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGSTVAELMESASISLKQAE
                     KNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
                     DGFEKQYVAYMEQNDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASL
                     VAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANA
                     IYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSAS
                     ETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQ
                     GRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVT
                     RVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRL
                     TEAVAVFRIQQQQQQQRETSAVVKNVTPATPRKMAVADSGENWETF"
     gene            64641..66791
                     /gene="btsT"
                     /locus_tag="IT892_000957"
     CDS             64641..66791
                     /gene="btsT"
                     /locus_tag="IT892_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter BtsT"
                     /protein_id="HAP3134196.1"
                     /translation="MDTKKIFKHIPWVILGIIGAFCLAVVALRRGEHVSALWIVVASV
                     SVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFGHHFAAIAGAG
                     PLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGPV
                     PGTIALFGCFLIMIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFIRPG
                     RVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALTFKDTTITFALIGYAFVSALLPVWL
                     ILAPRDYLATFLKIGVIVGLALGIVVLNPELKMPAMTQYIDGTGPLWKGALFPFLFIT
                     IACGAVSGFHALISSGTTPKLLANETDARFIGYGAMLMESFVAIMALVAASIIEPGLY
                     FAMNTPPAGLGITMPNLHEMGGENAPIIMAQLKDVTAHAAATVSSWGFVISPEQILQT
                     AKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHFGILFEALFILTALDAG
                     TRSGRFMLQDLLGNFIPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLW
                     PLFGISNQMLAAVALVLGTVVLIKMKRTQYIWVTVVPAVWLLICTTWALGLKLFSTNP
                     QMEGFFYMASQYKEKIANGTDLTAQQIANMNHIVVNNYTNAGLSILFLIVVYSIIFYG
                     FKTWLAVRNSDKRTDKETPYVPIPEGGVKISSHH"
     gene            66841..67044
                     /locus_tag="IT892_000958"
     CDS             66841..67044
                     /locus_tag="IT892_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HAP3134197.1"
                     /translation="MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSY
                     EEFFRERQNARYGGDGKGGMRCC"
     gene            67055..68011
                     /gene="yjiA"
                     /locus_tag="IT892_000959"
     CDS             67055..68011
                     /gene="yjiA"
                     /locus_tag="IT892_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313338.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HAP3134198.1"
                     /translation="MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVS
                     VDDQLIGDRATQIKTLTNGCICCSRSNELEDALLDLLDNLDKGNIQFDRLVIECTGMA
                     DPGPIIQTFFSHEILCQRYLLDGVIALVDAVHADEQMNQFTIAQSQVGYADRILLTKT
                     DVAGEAEKLRERLARINARAPVYTVTHGDIDLGLLFNTNGFMLEENVVSTKPRFHFIA
                     DKQNDISSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGV
                     QRLYSADWDRPWGDEKPHSTMVFIGIQLPEEEIRAAFAGLRK"
     gene            complement(68045..68347)
                     /locus_tag="IT892_000960"
     CDS             complement(68045..68347)
                     /locus_tag="IT892_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006686551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="HAP3134199.1"
                     /translation="MSMVKHKRGTSSTLDVQHEAELKALTNKSDEDIDYSDIPPSSDE
                     QWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKGYQTRLNAILREAMLRDQNKK"
     gene            complement(68334..68621)
                     /locus_tag="IT892_000961"
     CDS             complement(68334..68621)
                     /locus_tag="IT892_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="HAP3134200.1"
                     /translation="MPMEFEWDENKAKSNRVKHGIRFEDAVLLFDDPQHLSQQERIEN
                     GEYRWQTIGLVYGIVVILVAHTIRFESGNEIIRIISARKADRKERNRYEHG"
BASE COUNT        16261 a        18545 c        17206 g        16811 t
ORIGIN      
        1 atccccgcca ctttacaggt gctcgcatat cttcaacgca ccctattttt acccaagcct
       61 gcccacgggc aggcttttgg ggtggttagc gggtcaggtc gtcaaaaaac ttcttcacac
      121 catcaaagaa gctctttgag cgcgggctgt tgtgctcgcc ggttgggcca ccgaagcttt
      181 cttgcagctc ttgcagcagc tgtttctgct tctcgttcag gcctaccggt gtttcgacga
      241 caacgcggca cagcaaatca ccctgtgcgc caccgcggac agacttgacg cctttaccgc
      301 gcatacggaa aagcttaccg gtctgggttt cgccaggcac tttcagtttg acgcgaccat
      361 caagggtcgg tacttcgatt tcgccaccca gcgccgccat agcgaagttg atcgggactt
      421 cgcaatacag gttgttgcct tcacgctcga aaatcgggtg ctgtttaacc tgaacctgaa
      481 cgtacagatc gcctgccggt gcgccatgct cgcccgcttc accttcgccc gcaagacgga
      541 tgcggtctcc agtgtccacc cctgccggga ttttaacgga cagcgttttg ctgcgctcaa
      601 cacgaccatg accatgacat ttgttgcacg gatctttgat cagcgtaccg cggccctgac
      661 agtgtggaca ggtctgctgc acggcaaaga aaccctgacg catctgcacc tgaccagaac
      721 catgacaggt cggacaggtc tgcggctgtg tacctggttt tgcaccgcta ccgtggcaaa
      781 cgtcacactc ttccagagtc ggaatgcgga tctctttggt cacgccacgt acagcttctt
      841 cgagggtgag ctccatgtta tagcgtaaat cagcaccgcg cgccgcacgt tgacgaccac
      901 gtccgccgcc aaaaatatcg ccgaaaacgt caccaaaaat atcgctgaag tctgcgccgc
      961 cgccaaaacc gccgccgccc ataccacctt gctcaaacgc agcatgacca tactgatcgt
     1021 atgccgcacg tttttgcgag tcggtcagaa cttcataagc ttccttgatc tctttaaatt
     1081 tcgcctcggc ctcttggtca ccctggttac ggtccgggtg gtatttcatg gccaggcgtt
     1141 tgtaggcctt tttgatttca cgctcttccg ctgttttgga aacgcctaaa atctcgtaat
     1201 aatcttgctt agccatcttt tttaaattgc ccctagatga atgcacgggc ggagaggaaa
     1261 ttccccttcg cccgtgtcag tataattacc cgtttatagg gcgattattt tttgtctttg
     1321 acttcttcaa attcagcgtc gacaacatcg tcatctttcg cgttgtttgc agaagcatca
     1381 gcaccggcag tctgctgctg ggcatgttgc tgctgggcga tttccatcag tttctgggaa
     1441 acctgtgcca gctcctgcat tttcgcttcg atagcggctt tgtcttcacc tttcagagca
     1501 gtttccagtg cagtcagtgc agactcgata gcagttttgt cgtcagccgg cagtttgtcg
     1561 cctgcttctt caacctgctt acgggtgctg tgcagcagat ggtcgccctg gttgcgagtc
     1621 tgtaccagct cttcaaactt acggtcagct tcggcgttag cttctgcgtc gcgtaccatt
     1681 ttctggattt catcttcgtt cagaccagaa gaagccttga tggtgatctt ctgctcttta
     1741 ccgctgtttt tatctttcgc ggaaacgtgc aggataccgt cagcatcgat atcgaaggta
     1801 acttcgatct gcggcatgcc gcgcggtgcc gggttgatac catccaggtt gaactgaccc
     1861 agagatttgt tatcagccgc acgtttacgt tcaccctgca gcacatggat ggttaccgca
     1921 gactggttgt cttcagcggt agagaacacc tggctgtgct tggtcgggat agtggtgttt
     1981 ttcgcgatca gcgtcgtcat cacaccgccc atggtttcga tacccagaga cagcggggta
     2041 acgtccagca gcagtacgtc tttcacgtca ccagtcagaa caccaccctg aacagcagca
     2101 ccgattgcta cagcttcgtc cgggttaacg tctttacgcg gctctttacc aaagaactca
     2161 gcaactttct tctgaaccat tggcatacga gtctgaccac caacgaggat aacgtcgtcg
     2221 atatcagata cggacaggcc agcgtcctgc agtgcaactt tcagcggctc aatggaacgg
     2281 tttaccagat cttcaaccag gctttccagt ttcgcacgag tcactttgat gttcatgtgt
     2341 ttcggaccgg tcgcatctgc agtgatgtac ggcaggttaa cgtcggtctg ctgagcggaa
     2401 gacagttcga ttttcgcttt ttctgccgct tctttcaggc gctgcattgc cagcggatcg
     2461 ttgcgcaggt caatgccctg atctttcttg aattcttcaa ccaggtagtt gatcagacgg
     2521 ctgtcgaagt cttcaccacc caggtgggta tcaccgttgg tagccagaac ttcgaaggtt
     2581 ttttcgccgt caacttcgtc gatttcgata atagaaatat cgaaagtacc accacccagg
     2641 tcataaaccg cgatagtacg gttgccagta cctttgtcca gaccgtaagc cagcgcagct
     2701 gcggtcggtt cgttgatgat acgttttact tccagaccag cgatacggcc tgcgtctttg
     2761 gttgcctgac gctgagcatc gttaaagtat gccggtacgg tgataacagc ttcagttacc
     2821 ggttcaccca agtaatcttc agcggttttc ttcatttttt tcagcacttc agcagagatc
     2881 tgcggcggtg ccattttctg gcctttaact tcgacccatg cgtcgccgtt atcagcagca
     2941 ataattttga acggcatgat ggaaacatca cgctgtactt cttcgtcctg gaagcggcga
     3001 ccaatcaggc gtttaatcgc aaacagggtg ttttgcgggt tcgtcactgc ctgacgttta
     3061 gccggctgac caaccagagt ttcaccatcc tgggtatagg caatgataga aggcgtggtg
     3121 cgatcgcctt cggcgttctc cagcacacga ggagtggtgc catccataat cgctacacaa
     3181 gagttggtag tacccaggtc gataccaatt attttaccca tctaaacgtc tccactatat
     3241 attcggtcat catgtggttg tgagtctgta ataggggcga aacgtctggt ttcaactgcc
     3301 caatttcatt tttttgcaga ctcactcact gcggttgact actaaatggg gtcgtaaccc
     3361 acgtcatcaa gggggagatg caaaaatttt ttgtgctttt gcgcagaaat ttcgcgatat
     3421 agcaggacaa gacgtgaaac tgacagcaat tttattcata taaagaatga atcgcagcca
     3481 agacattcat caaaaaattg taataaaaag aaaacattac gcacctgaat cttctcttta
     3541 tcagcagtaa actagtgggt atccatcccc ctacctctcc ccactaagag aatccttatg
     3601 aaatccgttt ttacgatttc cgccagcctg gcgattagtc tgatgctgtg ctgcacggcg
     3661 caggcaaacg accataaaat cctcggcgtc attgcgatgc cacgtaacga aaccaacgat
     3721 ctggcgctga aacttcctgt ttgccgaatt gttaaacgca tacaactctc tgccgaccat
     3781 ggcgatttac agttaagcgg tgcatcggtt tatttcaaag ccgcccgtag cgccagtcag
     3841 agcctgaata ttccttcaga aataaaagaa gggcaaacca ctgactggat caacattaac
     3901 agcgataacg acaataaacg ctgcgtctca aaaatcacct tttccggtca tacggtgaac
     3961 tcatcggata tggccacgct gaaaattatc ggcgacgact aacgccagaa tatagaagcc
     4021 acaaaaaatg aatgttaatt acctgaatga ttcagatctg gattttctcc agcattgcag
     4081 tgaggaacag ttggcaaatt tcgcccgatt gctcacccat aatgaaaaag gcaaaactcg
     4141 cctctccagc gtactgatgc gcaacgaact gtttaaatcg atggaagggc atcccgagca
     4201 acatcgccgc aactggcagc tgattgctgg agaattacag cattttggtg gcgatagtat
     4261 cgccaacaaa ctgcgcggac acggtaaatt gtatcgggcc attttgctcg atgtttcaaa
     4321 acgattgaag ctgaaagccg acaaagagat gtctacgttt gagattgagc aacagttact
     4381 ggaacaattt ctgcgtaaca cctggaagaa tatggacgag gaacataaac aggagtttct
     4441 gcacgcggtc gatgcgaggg tgaatgagct ggaagagctg ctgccgctgc tgatgaaaga
     4501 caaattattg gcaaaaggcg tgtcgcattt gctttccagc caactgaccc gcattttacg
     4561 cacccacgca gcaatgagcg tacttgggca tggtttgctg cgcggcgcgg ggctgggagg
     4621 ccctgtaggt gcggcactaa atggggttaa agcggtcagc ggcagcgcct atcgcgtgac
     4681 gattccagcc gtactgcaaa tcgcctgcct gcgccggatg gttagcgcca ctcaggtctg
     4741 ataccggaaa ccggggaaaa ttttcatttt cccctcaaaa gatcgtagac actgccccac
     4801 tggctgatta ttatgccgcg ccctgaaaac actatagtta ttcagggaaa ttatttcacc
     4861 attcattcga tgatgatttt tgaggaatta tgggcaacac taagttggct aatccggcac
     4921 cgctgggcct gatgggcttc ggcatgacca ccattctgct taacctgcac aacgtgggtt
     4981 atttcgctct ggacggtatt attcttgcca tgggcatttt ctacggcggc atcgcgcaaa
     5041 tttttgctgg tctgctggag tacaaaaaag gcaacacttt cggtttaacc gcattcacct
     5101 cttacggttc tttctggctg acgctggttg cgattctgct gatgccgaaa ctgggtctga
     5161 ccgatgcgcc aaatgcacag ttccttggtg tctacctggg tctgtggggc gtatttacgc
     5221 tgtttatgtt cttcggcacg ctgaaaggcg cacgcgttct gcaattcgtt ttctttagcc
     5281 tgaccgtgct gtttgccctg ctggcgatcg gtaacattgc cggtaacgcc gcaatcatcc
     5341 actttgccgg ctggattggg ctgatttgcg gtgccagcgc aatctatctg gcgatgggtg
     5401 aagtactgaa cgagcagttt ggtcgcaccg ttctgccgat tggtgaatcc cactaattgt
     5461 tttgagatcc ccccgctcgg ggggattttt ttattcgcta acgtcgcgtc ttgcactctt
     5521 cggtctgaat gcagcaacca cttctggtgc cgtttcaacg tatggccctt ccagcaactg
     5581 aatgcagtac ggtacgctgg caaaaatacc gtgtaccaca acgttacccg cagcgtcctt
     5641 cacaccttcc agcgtctctt taatagactt cggctgaccg ggtaagttaa ggatcagcgc
     5701 ctgtttgcga atcacgccca cctgacgcga aaggatagca gttggtacaa aatgcaggct
     5761 gatctggcgc atctgttcac caaagccagg catctcgcgg tccgctactg ccagcgtcgc
     5821 atcgggcgtt acgtcacgac gcgccgggcc agttccgccc gtggtgagca ccagatggca
     5881 actcatttca tccaccagct cacacaacgt ttgctcgatg atcgcctgct catcggggat
     5941 taagcgggtt tccagttcaa acggcgtggt tagcgccgat gtcagccatt cttccagtgc
     6001 agggatacct ttatcctgat aaacgccgct ggatgcgcga tcagagatgg aaactaagcc
     6061 aatacgtaaa gtattcatca agatttttcc gtttaaacag tctcgttaaa cagaatgata
     6121 cactgcgaag ggagtgacag acaggcttca gaagaggtag cgtgaccgac ttcccggtca
     6181 cgctaagaat gattacagca gatcgccgat cattttttcc agtttttcct ggtcaatagc
     6241 aaacttacgg ataccttccg ccagtttatc tactgccatt ggatcctggt tgtgctgcca
     6301 caggaactcg gactcagtga tacgcgccgg acgcgctttc acttcgccgg tgtaagacag
     6361 tttacgttca atagcccctt cgctctcagc cagctctttc agcagtgccg gtgcgatggt
     6421 cagacggtcg cagcctgcca gttccagaat ttcgccgatg ttacggaagc ttgcgcccat
     6481 aaccacggtt tcataaccgt gctctttgta gtactggtag atttcagata cagaaaccac
     6541 acccggatct tctgccggag cgtactcttt cttatcggta ttcgctttgt accagtcaag
     6601 aatacggcca acaaacggcg agatcaggaa cacgcccgct tccgcacaag cacgagcctg
     6661 agcgaaggag aacagcaggg tcaggttaca gttgatacct tctttttcca gctgttctgc
     6721 agcacgaata ccctgccagg tagaagccag tttgatcaga atacgatcgt tgctaatacc
     6781 tgcatcgttg tagagtttga tcaggcgttt tgctttcgca attgacgctt cggtgtcata
     6841 ggaaagacgc gcatcaactt cagttgagat acggcccgga accagtttca ggatttccag
     6901 accaatattt actgccagtt tgtcggtcgc gtccacgatc tgctgcgcgc gatcgttgct
     6961 ctgctgtttc gcccaggcga cagcatcatc aatcaactta cggtattccg gaatctgcgc
     7021 tgcgttaaga atgagagaag ggttggttgt ggcatcctgc ggttgataca gcttcattgc
     7081 cgcgatgtcc ccagtgtcgg ccactacggt ggtgtactga cgaagggagg tcaatttgtc
     7141 cgtcatgata gtatttctct ttaaacagct tgttaggggg atgtaaccgg tctgccctga
     7201 tgatatcacg acgcaacgtc agcgcaaccg ccgacaagac ggttatcgcc aggcgagact
     7261 gtttcggatt tctgacactg cgttgatatc gcccgccatt tttatacaaa acctcatgta
     7321 tgctacgcag aagttatcaa gtacctcgta gcgtatatac ttcttaaaca attggtaacg
     7381 tttacacagg aaagtcatcg cgaccggcaa taagagggat atgcatgcca gattttttct
     7441 cctttattaa cagcgtcctt tggggatcgg taatgattta cctgctcttc ggcgcaggtt
     7501 gttggttcac ttttcgcacc ggatttgtgc agtttcgcta catccgccag tttggcaaaa
     7561 gtcttaaaaa tagcattcat ccacagccag gcggtttaac ctcatttcag tcattgtgta
     7621 ccagtcttgc ggcgcgcgtg ggtagcggca acctggccgg cgttgcgctg gcaattaccg
     7681 ccggtggacc tggagccgtc ttctggatgt gggttgccgc gtttatcggc atggcgacct
     7741 cgtttgccga atgttccctc gcacagcttt ataaagaacg tgatgccaat gggcagtttc
     7801 gtggcggacc ggcatggtat atggcgcgcg ggctggggat gcgctggatg ggcgttctgt
     7861 tcgccgtctt tttgctcatc gcctacggca taattttcag cggaattcag gcgaacgccg
     7921 ttgcgcgagc cctgagtttt tcttttgatt ttcccccgct ggtgacaggt attattctcg
     7981 ctgtctttgc tctgctggcg atcactcgcg gtcttcatgg cgtcgcccgg ctcatgcagg
     8041 ggtttgtccc gttgatggcg ataatctggg tactgaccag cctggtgatt tgcgtaatga
     8101 atatcgggca acttccccac gtcatttggt ctatttttga gagtgctttt ggctggcagg
     8161 aagcggcagg cggcgcggcg ggatatacct taagccaggc gattactaac ggttttcagc
     8221 gcagtatgtt ttccaatgag gcgggaatgg ggtcgacgcc aaacgcggta gcggcagcgg
     8281 cgtcctggcc tccgcatccg gcagcgcaag ggattgtcca gatgattggc atttttatcg
     8341 acaccctggt catctgtacg gcaagcgcca tgctgatatt actggcgggt aacggcacaa
     8401 cctacatgcc gctggaaggt attcagctta tccagaaggc gatgcgggtg ctaatgggtt
     8461 cctggggtgc tgagtttgtt accctcgtgg ttattctgtt tgccttcagc tccatcgttg
     8521 ccaactacat ttacgccgaa aacaatctct tctttttacg cctgaacaac cctaaagcga
     8581 tctggtgttt gcggatctgc accttcgcaa cggtcatcgg cggcaccttg ctaagtcttc
     8641 cgctgatgtg gcaactggca gatatcataa tggcctgcat ggctattacc aatttgaccg
     8701 ccattttact gctctcgcct gtggttcata ccattgccag tgattatcta cgccagcgta
     8761 aactcggcgt gcgcccggtg tttgatccgt tgcgttatcc ggatatcggc cgccagcttt
     8821 ctccggacgc gtgggatgat gtttcgcagg agtaatcaca actatcgatc aactcattct
     8881 ctttttttgc taaagtcggc ataaatttcc tgcaaggact ggatatgctg attcttattt
     8941 cacctgcgaa aacgcttgat taccaaagcc cgttgaccac cacgcgctat acgctgccgg
     9001 agctgttaga caattcccag cagttgatcc atgaagcgcg gaaactgacg cctccgcaga
     9061 ttagcacgct gatgcgcatc agcgacaaac tggcgagtat caacgccgct cgctttcatg
     9121 actggcagcc agatttcacg ccggagaatg cccgccaggc gattctggcg tttaaaggtg
     9181 atgtctacac cggcttgcag gccgaaactt tcagcgaaga caatttcgat tttgcccaac
     9241 agcatttgcg aatgctttcc ggcttgtatg gcgtactgcg cccgctcgat ttaatgcagc
     9301 cttatcgtct ggaaatgggg atccgtcttg agaatgcccg agggaaagat ctgtatcaat
     9361 tctggggaga tatcatcacc aacaagctga acgaggcgct cgcagcacaa ggcgataatg
     9421 tggtgattaa tctggcgtca gatgagtatt ttaaatcggt gaagccgaag aaattgaatg
     9481 ccgagattat caagccggtg ttcctcgatg agaagaacgg caaatttaag atcatcagct
     9541 tctacgctaa gaaagcacgc ggtctgatga gtcgttttat tattgaaaat cggctgacca
     9601 aaccagagca actgactggt tttaatagcg aaggttactt ctttgatgaa gcttcctcca
     9661 gcaatggaga actggtgttt aaacgctacg agcagcgtta agtttgcagt caatgccgga
     9721 tgcggcgtga acgccttatc cggcctacaa aagcatgcag attcaatata ttgcagaatt
     9781 cacgtaggcc tgataagacg cgccagcgtc gcatcaggcg ctgaatgccg gattgttacc
     9841 cggcatttgt catttagcgg tgatgtttgc ctggaccatg accgccgtga tgatcatgag
     9901 gagctttctt atggtgacgc ggcggtggcg gcggtccgtg tgggtgccag cgattgcctc
     9961 gccattcata atgttgtttc caccagccgt ggtcgcgcca gtgaccgcca tcccagtaat
    10021 agccacgatt atcacgatcg cctatctgta attttactga cgggactaac gtaatttccg
    10081 cagcctgcgc tgccatggga gcgaccagaa ccagggaaag tgcgagtacg atagattgca
    10141 tctttttcac aggttactcc ttttatcatt gcccgttatg ggtcgatatc cggagattac
    10201 gcgatgagaa cggcggttgt tattctccgc aatcctaata tctaagttac cgcatttatt
    10261 gagaatttct cctttttccc tgtcgtttct ctccatattt tcttcacaaa aaagccgggc
    10321 tgcataaaag caaacccggc ctgattgaga taatgaaaag atattactga tgattcatca
    10381 tcaatttacg caacgcagca aaatcggcgg gcagattatg tgaaagcaag ggtaaatcag
    10441 cacgttctgc cagctctttt ggcagatcca acgtttcacc gagaatcgct tccacgctct
    10501 ctttaaattt cgccggatgc gcggtgccga ggaacaagcc atattcgcct ggattcaact
    10561 ggtcacgcag cgcacgatac gctacggcag cgtgcggctc cgaggtgtag cccagttctt
    10621 ttaactcacg cattgtctgt tgcgtggttt catcatccac ggctgcataa cccagctctt
    10681 tcagttgcca gattttgcgg cggaacaact cttcaacacg cggccagttg tttggctgac
    10741 tcacgtccat cgcgttggat aacgtcgcct gagtcgcttt gggtgaccac tgaccatcgt
    10801 gcaggaaacg tggcacggta tcgttcacgt tggtcgcagc aataaaacgt ttcaccggca
    10861 gaccgagtga cttcgccagc agacccgccg tcaaatcgcc gaagtttccg cttggcaccg
    10921 agacaaccag ctggttgcgc gcttcctgcg gcagctgcgc aacagcttca aagtagtagc
    10981 aaatctgcgc cagcaaccgg ctgatgttaa tcgagttagc tgagtttaac cccagcgcca
    11041 ctttcagctc ttcatcatca aacgcctgct tcaccagcgc ctgacaggca tcgaaatcgc
    11101 cgtcgatggc aacagtttcg atattgccgc ccaatgtaca gaacagtttt tcttgcagtg
    11161 gactgatttt gcctcgtgga tagaggataa ccactttcac attcggtaaa ccgtagaaag
    11221 catgagccac tgccgctccg gtatcaccgg aggtcgcggt cagaatggtc actggcttat
    11281 cgcccgcaat atgggtcagc atttgtgcca taaagcgacc gccgaaatct ttaaatgcca
    11341 gcgttggccc gtggaacaat tccagacaac cgacatcgct ttcaacattg gcgaccggag
    11401 ccgggaaggc aaacgccgcg cgcacgcgct cttccaggat ttcctgcggg atttcatcac
    11461 caataaacgc cgagaggatc ttcgcactgc gggtgacaaa atccagcttc agcatctcat
    11521 caatttcagt caggctgaat tccggcaggt catgcggaaa aaacagcccc tgatttttgc
    11581 ccaacccctg ggttacggct tgcgcaaagc tgacctgctc gctgtgatct ttcagattgt
    11641 agagtttcat ttagttttcc agtactcgtg cgcccgccgt atccagccgg caaatatgaa
    11701 caaaaccttc ctgattttgc aggtagttct tacccaacca gtcggcaacg cgctgggcgg
    11761 tatccggctt gtcacacaga gcgaacaagg tcgggccgga gccggagata ccgctcgcta
    11821 ccgcgccgat ttccgcgacc gcctgccgcg cctgccggaa gccaggcagt aaccgttcac
    11881 ggtagggttc tgcgataaca tctttcatca gcttcgcggc aagctcaggc tgacgggaat
    11941 agcaggcgtg aatgaagcct gccagatgtc gcccgtgcgc aatgcaatcc tggcggcgat
    12001 actgcgccgg taaaatagcc cgggcttctg ccgtcgagac tttaatcccc ggatacgcca
    12061 gcacccacag ccactcatca aaccctggca cttgctggct gatgatgtcg ttttcttcga
    12121 tcatcaactg cataccacca agaaaacacg gtgccacgtt gtcgtaatga atgctgccgg
    12181 agattcgtcc ttccagctcg cccatcaaag ccagcaaacg agtgtcatta agcggcttgc
    12241 cacagtgttc attcatcgcc atcagcgccg cgaccaccga acaggcgctg gagcctaagc
    12301 ccgagccgat cggcatattc ttttccagag tcatcgccac tggaatttgc ttgccaagct
    12361 cctggcaaaa acgctcccag cactgataaa cgatattttc ccgtggttct gacggcagct
    12421 tatcggcaaa gcgtccgagg ttgttgagac tgaatgtctc tgccgcctca accgtgacta
    12481 catctccgag caatgcacca tcaacaggtg tcaccgccgc cccgagcaca tcaaacccga
    12541 cgctcatatt ggcactggaa gccggggcat aaactttaac catgtcagac tcctaacttc
    12601 catgagaggg tacgtagcag atcggcaaag acaccggcag ctgtaacgtc attgcccgca
    12661 ccatatccgc gcagcaccaa cggcagcggc tgataatagt ggctataaaa ggccagggcg
    12721 ttttcgccat ttttcacttt gaacagcgga tcattaccat ccacttcggc aatcttcacg
    12781 cggcaggcac catcttcatc aatattgcca acatagcgca aaacttttcc ttcatcacgg
    12841 gccttcgcca cgcgcgcggc aaagagatcg tcgagctgtg acagattcgc cataaaagcg
    12901 gcaacatcac cctcagcgtt aaactctgcg ggcagcacag gttcaatttc aatatccgcc
    12961 agctccagtt cacgtcccgt ttcacgagcg agaatcaata gcttacgcgc tacatccata
    13021 ccagaaagat catctcgcgg atccggttcg gtataaccca tttcccgcgc cagagtagtc
    13081 gcctcggaga aactcatgcc ttcgtctaac ttgccgaaga tataagaaag cgaacctgaa
    13141 agaatgccgg agaacttcat caattcatca ccagcattga gcagattttg caggttctca
    13201 ataaccggta atccagcccc aacgttggtg tcatagagga atttacgccg cgatttttcc
    13261 gccgcatgac gcaacagatg gtagtaatcc atcgacgagg tgttggcctt tttgttcggc
    13321 gtgacaacgt ggaaaccttc gcgcaagaag tcggcatatt gatccgccac tgcctggctg
    13381 gaagtgcagt caacaatgac cgggttcagc agatgatatt ctttcacgag gcgaattaag
    13441 cgcccgagat taaacggctc tttggcttgc gccagttctt cctgccagtt ttccaggttt
    13501 aggccatgca cattggtaag cagagccttc gagttggcaa cgccgcagac acgtaagtcg
    13561 atatgtttat tcttcagcca gctttgttga cgcttcagtt gctccagcag cgcaccgcca
    13621 acgccaccga cgccaatcac aaatacttcg ataacctgat cggtattgaa cagcatctga
    13681 tgagtaacgc gcacgccagt ggtcgcatca tcgttattta ccacgacaga gattgagcgt
    13741 tcagaagatc cctgagcaat ggcgacaatg ttgatattgg cgcgggccag cgcggcaaag
    13801 aatttcgccg agatcccacg caaggtgcgc ataccatcac ctaccaccga gataatggcc
    13861 agccgttccg tcaccgccag cggctccagt aagccttctt tcagttccag gtagaactct
    13921 tcctgcattg cccgttcagc tcgcacacag tcgctttgcg gaacgcagaa actgatactg
    13981 tattcggaag atgattgcgt aatcagcacc acggaaatac gggcgcgtga catcgctgca
    14041 aacacgcgcg ccgccatgcc gaccattcct ttcatccccg ggccggaaac gctgaacatt
    14101 gccatgttat tcagattgga aatgcccttg accggtaatt cgtcttcatc acggctggca
    14161 ccaatgagcg tacctggtgc ttgaggattt ccggtatttt taatcaggca agggatctgg
    14221 aactgggcga tgggggtaat ggtgcggggg tgaagaactt tagcgccgaa gtaggaaagc
    14281 tccatcgctt cctggtagga catcgacttc aacaacctcg catcgggcac ctgacgcggg
    14341 tcgcaggtat agaccccgtc aacgtccgtc caaatctcgc aacaatcggc gcgtaaacag
    14401 gcagccagca ccgccgcgga gtagtcggaa ccgttgcgtc caagcaccac cagttcgcct
    14461 ttttcattac cggcggtgaa acctgccatc agcaccatgt gatcagccgg aatacgactt
    14521 gccgcaatac ggcgggtgga ctcagcaata tcgacggtag attcgaggta atgccccact
    14581 gccagcagtt tttcgaccgg atcgataacg gtaacgttgt gaccacgcgc ttctaacacg
    14641 ccggccataa tggcgatcga cattttctcg ccacggcaaa tcagcgcagc gttgatgcta
    14701 tccgggcact gccccaacaa actaatgcca tgcaggacat gttttatttg ggcaaattcc
    14761 tggtcgacga aagttttcag ttgcgccagc gggaatcccg gctgggcggc ggtgagtccc
    14821 gtcagaagtt cggcaaaaat acgttcggca tcgctgatat tgggtaaagc atcctggccg
    14881 ctaatggttt tttcaatcat cgccaccagg tggttggtga ttttggcggg ggcagagagg
    14941 acggtggcca cctgcccctg cctggcattg ctttccagaa tatcggcaac ccgcagaaaa
    15001 cgttctgcat ttgccactga tgtaccgccg aacttcaaca ctcgcatggt tgttacctcg
    15061 ttacctttgg tcgaaaaaaa agcccgcact gtcaggtgcg ggcttttttc tgtgtttcct
    15121 gtacgcgtca gcccgcaccg ttacctgtgg taatggtgat ggtggtggta atggtggtgc
    15181 taatgcgttt catggatgtt gtgtactctg taatttttat ctgtctgtgc gctatgccta
    15241 tattggttaa agtatttagt gacctaagtc aataaaattt taatttactc acggcaggta
    15301 accagttcag aagctgctat cagacactct ttttttaatc cacacagaga catattgccc
    15361 gttgcagtca gaatgaaaag ctgaaaaata cttactaagg cgttttttat ttggtgatat
    15421 ttttttcaat atcatgcagc aaacggtgca acattgccgt gtctcgttgc tctaaaagcc
    15481 ccaggcgttg ttgtaaccag tcgaccagtt ttatgtcatc tgccactgcc agagtcgtca
    15541 gcaatgccat ggctcgttcg cgtaaagctt gcagttgatg ttggtctgcc gttgtgtcac
    15601 ttttcgccgg ttgttgtatt aatgttgcta attgatagca atagaccatc accgcctgcc
    15661 ccagattgag cgaaggataa tctgccacca tcggcacacc agtaagaacg tcagccaacg
    15721 ctaactcttc gttagtcagc ccggaatctt cgcgaccaaa caccagcgcg gcatggctca
    15781 tccatgaaga tttttcctct aacagcggta ccagttctac tggcgtagcg tagtaatgat
    15841 atttcgcccg actgcgcgca gtggtggcga cagtgaaatc gacatcgtgt aacgattcag
    15901 ccagtgtcgg gaaaacttta atattatcaa taatatcacc agatccatgt gcaacccagc
    15961 gggtggctgg ctccaggtgt gcctgactat cgacaatccg cagttcgcta aaccccatcg
    16021 ttttcattgc ccgcgccgct gccccaatat tttctgctct ggcgggtgcg accagaataa
    16081 tcgttatacg catattgcca ctcttcttga ccaaatgacc gcgaacaggg tgatcactgt
    16141 caacttatta cgcggtgcga atttacaaat ccttaacgta agtcgcagaa aaagcccttt
    16201 acttagctta aaaaaggcta aactatttcc taactgtact aacggttgaa ttgttaaaaa
    16261 atgctacata tccttctgtt tacttaggat aattttataa aaaataaatc tcgacaattg
    16321 gattcaccac gtttattagt tgtatgatgc aactagttgg attattaaaa taatgtgacg
    16381 aaagctagca tttagatacg atgatttcat caaactgtta acgtgctaca attgaacttg
    16441 atatatgtca acgaagcgta gttttattgg gtgtccggcc cctcttagcc tgttatgttg
    16501 ctgttaaaat ggttaggatg tcagccgttt ttgacactgt cgggtcctga gggaaagtac
    16561 ccacgaccaa gctaatgatg ttgttgacgt tgatggaaag tgcatcaaga acgcaattac
    16621 gtactttagt catgttacgc cgatcatgtt aatttgcagc atgcatcagg caggtcaggg
    16681 acttttgtac ttcctgtttc gatttagttg gcaatttagg tagcaaacat gcagaccccg
    16741 cacattctta tcgttgaaga cgagttggta acacgcaaca cgttgaaaag tattttcgaa
    16801 gcggaaggct atgatgtttt cgaagcgaca gatggcgcgg aaatgcatca gatcctctct
    16861 gaatatgaca tcaacctggt gatcatggat atcaatctgc cgggtaagaa cggtcttctg
    16921 ttagcgcgtg aactgcgcga gcaggcgaat gttgcgttga tgttcctgac tggccgtgac
    16981 aacgaagtcg ataaaattct cggcctcgaa atcggtgcag atgactacat caccaaaccg
    17041 ttcaacccgc gtgaactgac tattcgtgca cgcaacctgc tgtcccgtac catgaatctg
    17101 ggtactgtca gcgaagaacg tcgtagcgtt gaaagctaca agttcaatgg ttgggaactg
    17161 gacatcaaca gccgttcgtt gatcggccct gatggcgagc agtacaagct gccgcgcagc
    17221 gagttccgcg ccatgcttca cttctgtgaa aacccaggca aaattcagtc ccgtgctgaa
    17281 ctgctgaaga aaatgaccgg ccgtgagctg aaaccgcacg accgtactgt agacgtgacg
    17341 atccgccgta ttcgtaaaca tttcgaatct acgccggata cgccggaaat catcgccacc
    17401 attcacggtg aaggttatcg cttctgcggt gatctggaag attaatcggc tttaccaccg
    17461 tcaaaaaaac ggcgcttttt agcgccgttt ttatttttca accttatttc cagatacgta
    17521 attcatcgtc cgttgtaact tctttactgg ctttcatttt cggcagtgaa aacgcatacc
    17581 agtcgatatt acgggtcaca aacatcatgc cggccagcgc caccaccagc acactggttc
    17641 ccaacaacag cgcgctatcg gcagagttga gcagtcccca catcacacca tccagcaaca
    17701 acagcgcgag ggtaaacaac atgctgttgc gccagccttt caataccgcc tgcaaataaa
    17761 taccgttcat taacgcccca atcagactgg cgattatcca tgccacggta aaaccggtat
    17821 gttcagaaag cgccagcaaa agcaaataaa acatcaccaa tgaaagcccc accagcaaat
    17881 attgcattgg gtgtaagcgt tgcgcggtga gcgtttcaaa aacaaagaac gccataaaag
    17941 tcagcgcaat cagcagaatg gcatacttag tcgcccggtc agttaattgg tattgatcgg
    18001 ctggcgtcgt cactgcgacg ctaaacgcgg ggaagttttc ccagccggta tcattgcctg
    18061 aagcaaaacg ctcaccgaga ttatttgcaa accagctgct ttgccattgc gcctgaaaac
    18121 ctgactcgct aacttcccgt ttggctggca aaaaatcacc taaaaaactg ggatgcggcc
    18181 agttgctggt taaggtcatt tcgctattac gcccggcagg caccacagaa agatcgccgg
    18241 taccgcttaa attcagggcc atattcagct tcaggttctg cttccgccag tccccttcgg
    18301 gtaaagggat atgcacgccc tgcccgcctt gctctaaccc ggtgccgggt tcaatggtca
    18361 gcgccgttcc gttaacttca ggcgctttca ccacaccaat accacgcgca tccccgacgc
    18421 taatcacaat aaatggcttg ccaaaggtga tatttggcgc gtcgagttcg ctaagacgcg
    18481 aaacatcgaa atcggctttt agcgttaaat cactgtgcca gacctgaccg gtataaatcc
    18541 ctatcttgcg ttcttccacg ttctgattgc catcaaccat caatgactca ggtaaccaaa
    18601 aatggataaa acttcgtttc cgctccacgg ttttatcctc ttcctgcacc gtataaagct
    18661 cggtcacagg aatagcgata agcggcccaa cgagtttttg cggcccgctg gtactttggc
    18721 gaatcgcatc ttccacatcg ctacggtaat cggcacgttc gacaatcact tgccgaatca
    18781 gcattatcgg aatcaacaac agcaatactg caccaaacaa ggtggtcatt ttccagaaca
    18841 ggggggattt caacatagtc ttctcctttg caatggcagc aggttacgaa ggctatgtgg
    18901 gaagaatttg aagctatgtg aagtgacggt gaagtcgaag cgaggccagc acgccacctt
    18961 cctgcacgtt gcgcagcgtg acttcgccgt taaacaaacg ggcgacctca ctgacgaacg
    19021 ccaaccccag accgctgctt ttttgcccat ttgcacgcgg caaagagtaa aagcgttcaa
    19081 aaatacgtga cagcgcgtag tcaggaatac cactaccggt atccagcacc ttaagggcga
    19141 cgtgttcctg atccacttcg gcgcttagcg ttatgcgacc gctctcgggg gtaaaatcga
    19201 tggcgttatc cagtaaattc cccagcgcct gctccagtaa cgccggttca gcagcaacat
    19261 taacctcagt gggcataaca tgtagagtga tgtttttttc tgccaactgc acggtgcgcg
    19321 cttcgctgac gcggcgaaat aatgccgcca catcaacaac agtcaaaacg acttcctgac
    19381 gattctccag tcttgcctgg cgtagtaacg tttccaccag tgcctgcatt cgcgcatttt
    19441 gcgtcagaat gttgtcggta aaacgagcca ccacttccgg tggcggacct tcgcgtaaaa
    19501 tttccgccgc gccacgaatc gccgccagtg ggctttttag ctcatgagtt aacgcataaa
    19561 catactgctc aatatagttt ttcccttcca gcttcacgcg catactttcc agcgcctgcg
    19621 caagcttacg caactcgcta ctgccgagtt caggaagagg aacgggctta ttgtcagtga
    19681 cggaatcggc atagcgagtg agccgggcaa tggagcggtt gatccaccaa accatgcctg
    19741 cgccaatcac cagtgcaatc cccagcaaaa tggcgctggc ccataaaatt cgccgctcgc
    19801 tacgcttaat gaccggagcc atcgccgcgt tcggtttgcc tacgctcaaa acgccaataa
    19861 gccgcgagcc gtccataatc ggcgcggcaa catacatcac cgaactttcg ggatcggcag
    19921 gattttgcaa cgtgctgcgc gcaccatact gaccacgcaa cgttagccag acgtcattcc
    19981 agcgcgaata atcctgccca acggctttat ttgccgaatc gaacaatact ttaccctgcg
    20041 aatcggtcat atagacatga tattcattgc gcactttgtt aatgccaccg atattggcgc
    20101 gaaacgggcg atgttgtagc tgattaaacg cctgcgccag ttgcccatgc gttgggtccc
    20161 cagagagcaa atcgggacgc gccagctccg ccagcaacgt tgcggtgtcg atcaacgtcc
    20221 cctccgttgc tcttcgcacg cccggtttaa cttctttgac aaaaatagcc agtacgaacc
    20281 aggccgccac cgccaccagt aaaaaatagc ccagcagcaa ccgcatgccg atacgcatta
    20341 caggcccctc aggctatatc ccatgccgcg atgagtatta atcggtgaaa gatcggggtt
    20401 gatggcgcgc agcttggcac gcaacgtttt aatgtgggta tcaacggtgc gatcgtaggt
    20461 gtcctgcgca tcttcccaca cgctatccat tagttgctgg cgggaccaga cgcggcctgg
    20521 cgacttgagt aacgtcttca gcaataaaaa ctcataccgc gtcagcgtta atggcgtgtc
    20581 aaaccagctg atctgcgccg cgggttcatt caattcaaaa tgaccaatac ggatgacggg
    20641 agacggcgac gagaacttct tcacccgacg cagtaaggtg cgcaccctgg cgcacacttc
    20701 gcggggtgaa aacggtttag ccacatagtc gtcagcgcca atttccagcc caagcaggcg
    20761 atcgacctct tcacttcggg ccgtcaggaa cagtacaggt aacgccggat ggagcgccag
    20821 taactggcgg cataattcaa agccgctgat atcaggcaaa ccaacatcga gaatcatgac
    20881 gtcgggagcc tgctggcgag ctttatccag caccggcaag cctcgctcaa agacctcgac
    20941 ggcaaaacct tcctgctgca acatgtagac cagcgtgtcg gctatccctt gctcatcttc
    21001 cactaaccag accgtttccc gttgcataaa tcgcctctgt tattgccgcc acggcatgac
    21061 aggaaccgcg ctaatcgcgt ttttcggcga accttctaca actttgtcgg agtaagccag
    21121 ataagcgagc gcgttgcgtt tggcgtcata aaagcgcacg acctgtaacg acttaaagac
    21181 cagggacgtg cgttttttga atactacctc gccctgagct ttgccgtttt taatacgatc
    21241 cgacagttca atcggcccga cttgctgaca agaaatagcc gcatcggagg tatcttccgc
    21301 cagacccaat ccccctttaa taccacctgt tttcgcccgg ctcacataac aggtgacatt
    21361 tttcacatcg ggatcgtcaa aggcttccac aacaattttg tgatccgggc cgatcatttt
    21421 aaatacggtg tcgaccgaac caatctcttc tgcatgagcc aatggcccca gcattatcag
    21481 gcttaaagac aggatcaaat gcttgtattt catattgtta ccatttttat ctattacacg
    21541 agcaattagt tcgtcacggt aaataacata ttgattaaga acaaaatctc aatactttta
    21601 tttccgtcaa gacctaaaac atactctact aagaaaaaaa cactgaatgc taaaacagca
    21661 aaaaatgcta ttatccaatt acctgatgtc aggtgctcgt tgttgaaagg atgaggatat
    21721 tttatggatc aggccggcat tattcgcgac cttttaatct ggctggaagg tcatctggat
    21781 cagcccctgt cgctcgacaa tgtagcggcg aaagcaggtt attccaagtg gcacttacag
    21841 agaatgttta aagatgtcac tggccatgct attggcgcgt atattcgtgc tcgtcgtttg
    21901 tcgaaatcgg cggtcgcact acgcctgact gcgcgtccga ttctggacat cgcgctgcaa
    21961 taccgcttcg actctcaaca gacatttacc cgcgcattca agaagcagtt tgcccagact
    22021 cctgcacttt accgccgttc tcctgaatgg agcgcctttg gtattcgccc gccgctgcgt
    22081 ctgggtgaat tcactatgcc agagcataaa tttgtcaccc tggaagatac gccgctgatt
    22141 ggtgttaccc agagctactc ctgttcgctg gagcaaatct ctgatttccg ccatgaaatg
    22201 cgttatcagt tctggcacga ttttctcggc aacgcgccga ccattccgcc agtgctctac
    22261 ggcctgaatg aaacgcgtcc gagtcaggat aaagacgacg aacaagaggt attctatacc
    22321 accgcgttag cccaggatca ggcagatggc tatgtactga cggggcatcc ggtgatgctg
    22381 cagggcggcg aatatgtgat gtttacctat gaaggtctgg gaaccggcgt gcaggagttt
    22441 atcctgacgg tatacggaac gtgcatgcca atgctcaacc tgacgcgccg taaaggtcag
    22501 gatattgagc gatactaccc ggcagaagac gccaaagcgg gagatcgccc aattaatctg
    22561 cgctgtgaac tgctgattcc tatccgccgt taacgctgca gctcatctaa tgcaggggcg
    22621 tccagatgcg agatgtcccc tgcggtttca acgacccagc cagacgccag ccacaggctt
    22681 tcctgataat ccacgcgcga aatagaacag ttacgcagac gtaagcggcg ctctgcccat
    22741 gctggtaatc cgagaatcgt actcaccagg catcccagtg caataccatg actcaccagc
    22801 agcggtcggc ttccctgcgg taagtcccgg caagattcca gtgccgcatt gacgcgatcg
    22861 ctgagctcct gcattgactc gccttcagga atacgcccgt caacggtgcc attgaccagc
    22921 tgccgacgcc agttctcttc ttcttcggtc agagaatcga tatgtctttt ttccagcaca
    22981 cccatgttta attcacgcag gcgagaatca aagatgatgt cacagccgca ggcctgggcg
    23041 atgatttccg ccgtacgccg ggtgcgccct aaatcgctac tgatgatatg cgtaatgcca
    23101 agctctttgg cacgcgtcgc cacctgcatc gcctgttgct cacctttggc ggtcagcggg
    23161 ctgttagact ggccctgaat acgtcgctcg gcgttccact gcgtttcacc gtggcggact
    23221 aggtatacct gtaacatgct ttttttccgt atactgctgt aacgttaatt ttctgagtaa
    23281 tgctgattat gcaccaagtt gtctgtgcga ccaccaatcc cgctaaaatt caggccattc
    23341 tgcaggcatt tcacgagatc ttcggcgaag gatcctgcca tattgcatcc gttgccgtcg
    23401 agagcggtgt accggaacag ccctttggca gtgaggaaac gcgcgctggc gcacgaaatc
    23461 gggtagcaaa tgcccgccgt ttacttccag aggctgattt ttgggtggcg attgaagctg
    23521 gcattgatgg cgacagcact ttcagttggg tggtgattga aaacaccagc cagcgcggcg
    23581 aggcgcgttc ggcaactttg ccgttgcctg cggtgatatt ggaaaaagta cgtgaaggtg
    23641 aggcgcttgg tcccgtgatg tcgcgttata ccggtattga tgagattggt cgtaaggaag
    23701 gggcgatcgg cgtgtttacc gccgggaaac tcactcgcgc cagcgtctat caccaggcgg
    23761 tgatcctggc gctgagtccg tttcataatg cggtgtatta agcgcctgat gcgacgctgc
    23821 cgcgtcttat catgcctacc aaacatattg aaattacggg tatttgtagg acggataagg
    23881 cgttcacgcc gcatccggca ttcggtgcac gatgcctgat gcgccacgtc ttatcaggcc
    23941 aacaaaatca atcgcttttc agcaacacct cttccagcca ctggcgcagc tcaacgggcg
    24001 cggctttcag gctgttagat ccacgcgtaa tcgtcgcgat gcccgcgccg agttcatttt
    24061 ttaactcacg ctggctcatt tcgccgcgca acagctcttc gacaatacgc acgcgagtcc
    24121 ccaacgcttc gcgctcatct ggcgtcagca tcaggtttaa caacggtaaa tggagatcgt
    24181 tttggtaggc attcttaagc aggtcgacaa aacgtaacca ctcctggtga cgctgttctg
    24241 ccatcgctgc tgaatagggt gattgttggg ccataatatg tcgccattgt tagcggggga
    24301 agcaaaatgc ctcccccggt tgtactcgct aaagagtacg atagcatatc ataaacgtgc
    24361 ggatcagtaa cgacgtcccc attccgtggc gctcatcaac gtcggtttat cccccatgaa
    24421 ataacggtag taagcgtcat aagccagcac gttcttcaca taaccgcgcg tctcggagaa
    24481 cggaatactc tcgacaaatg ccacagcgtc gatacgcccg gcgctgttgc caagccaggt
    24541 tcgcacccgt ccaggtccgg cgttataagc tgctgaggag aaaatacggt tattgccaaa
    24601 ctgctgataa acatattgca ggtaactggt gccaatgttg atattcgttt ccggatccag
    24661 caattgccca gggctgctat aaccaggaat agagaacatc ttcaccgtat gggtcgctgt
    24721 accaggcata atctgcatca ggccgctggc ccctaccggt gatttcactt tcggattcca
    24781 ggcgctctcc tgacgggcaa tcgccatcgc atagctttgc gggatctctt tcccactggt
    24841 gtaacgtttg aaaagatcgt tgtaagccag cgggaatcgc tcttccagat gatcccaaag
    24901 cttcccggcg atcgttgcct gaacgctaag atcccaccat tggttattga aagcataccg
    24961 agccagttga gcctgctctg tttttgactt gctcttcacc agattggccc actcgctacg
    25021 cgcggtgtta tcgagattcc agtacatcaa ctcgcgcacg cgcgccatct ccggcccctg
    25081 agtcagggcg ctgtcaacat tctgcggcgc tttatcaatc ttcagctcat actcttctcc
    25141 gatgcgttgt gctgcaacca tcgggtagaa accacgctgt tgcatgagtt gatgcaaaat
    25201 ctctttcgct tcagcttcac gtccgcgttc cagcaataaa tccgcctgcc agtaacgcca
    25261 ttcatctttc tcttttgctt ccatcggcag acgcgccagc caggtattca ggccgcgacg
    25321 atcgccggtg ccaagtgcca ttcgcacacg gcgttcaatc aacgacgtgg attgcgagcg
    25381 cataatggcg tcatcgcgcc atttcgcctg ctcgtcggtg acatcgttgc ccatcaaacg
    25441 ccaggcgacg atatcgcgca gctcctgaat ctgatcttca ttaagctgct gcgcctgggc
    25501 aagcgacggg atcatcagcc gtgcattttc agcatcctgc cgcgccacac tggcaaacgc
    25561 caccgctgcc atttgacggg taaaatcggt cgctccggtt gtacgcgcga aggtcagtac
    25621 cgtattaggg ttattcgcca gtgaaatgat tgccgaggcg atagtctggt aatcggcagg
    25681 catctgccct gccagcactg ttaccaggcc agtgttaccc gctttcatcg ccagacggat
    25741 acgctctaaa tacgccagcg gatcttgttt acctgacgca cgccagacgc taaataactt
    25801 gtcacaggca ttaggctggc tcttgccggt tagccacagc tctttcgccc cttgccaggc
    25861 ttcttcactc tgcccggtgt tccatttcgc atagtagtaa ttacattgcg cttcggtagt
    25921 tccgggcttt tccgggctaa aggctaacaa gccacgccag tcttcacgcc gcgccagttc
    25981 attgacgaaa cgagattgca gcgtgcgagc gggaggaagc gtggggttag cgcgaacaaa
    26041 gttagtgacc gtcaccgccg gttgattcat cagatcatcg gtgatctggc ggtattccag
    26101 gtagggataa agcggataat ccttcagtcc aggcatcatt tgttcgacca catccatctg
    26161 tcgattatcc caggcctgct tgatttgcgc gtaacggcta cgctgctcat ccagtgagtc
    26221 ggctcgcgcc acgctgctga ccgtcagcag acagacaccg gcagccaaca gccgccaggt
    26281 aacttgtttg gctttttcca caagcgcatc ctctaagtgt aaatacatca atgcagcgtc
    26341 atgccgcgta atagatttat gctaaccagt cattgccgtt tacgccacgt tacggacact
    26401 tttttacttt tactgcgaag gtgatcgacc aactgggatt aggcggggaa aaaggctaca
    26461 cttcgccttt gaaaactcat catcacgata aacatagagg cgaagtccaa cgtggctcaa
    26521 ttcgtttata ccatgcatcg tgtcggcaaa gttgttccgc cgaaacgtca tattttgaaa
    26581 aacatctctc tgagtttctt ccctggggca aaaattggtg tcctgggtct gaacggcgcg
    26641 ggtaagtcta ccctgctgcg cattatggcg ggcattgata aagacatcga aggtgaagca
    26701 cgtccgcagc cagacatcaa gattggttat ctgccgcagg aaccgcagct gaacccggaa
    26761 cacaccgtgc gtgagtccat tgaagaagcg gtttctgaag tggttaacgc cctgaaacgc
    26821 ctggatgaag tgtatgcgct gtacgccgat ccggatgccg attttgacaa gctggccgct
    26881 gaacaaggcc gtctggaaga gatcattcag gctcacgacg gtcataacct gaacgtacag
    26941 ctggagcgtg cggcggatgc gctgcgtctg ccggactggg acgcgaaaat cgctaacctc
    27001 tccggtggtg agcgtcgtcg cgtggcgttg tgccgcctgc ttctggaaaa accagacatg
    27061 ctgctgctcg acgaaccgac caaccacctg gatgccgaat ccgtggcctg gctggaacgc
    27121 ttcctgcacg acttcgaagg caccgttgtg gcgattactc acgaccgtta cttcctcgat
    27181 aacgttgcag gctggatcct cgaacttgac cgcggtgaag gtattccgtg ggaaggcaac
    27241 tactcctcct ggctggagca gaaagatcag cgcctggcgc aggaagcttc acaagaagcg
    27301 gcgcgtcgta agtcgatcga gaaagagctg gagtgggtac gtcagggaac taaaggccgc
    27361 cagtcgaaag gtaaagcacg tctggcacgc tttgaagagc tgaacagcac cgaatatcag
    27421 aaacgtaacg aaaccaacga actgtttatt ccacctggac cgcgtctggg cgataaagtg
    27481 ctggaagtca gcaacctgcg taaatcctac ggtgatcgcc tgctgattga tgacctgagc
    27541 ttctcgatcc caaaaggggc aatcgtcggg atcatcggtc cgaacggcgc gggtaaatcg
    27601 accctgttcc gtatgatctc tggtcaggaa cagccggaca gcggcaccat cactttaggt
    27661 gaaacggtga aactggcatc ggttgatcag ttccgtgact caatggataa cagcaaaacc
    27721 gtttgggaag aagtttccgg cgggctggat attatgaaga tcggcaacac cgagatgcca
    27781 agccgcgcct acgttggccg ctttaacttt aaaggggttg atcagggtaa acgcgttggt
    27841 gaactttccg gtggtgagcg cggtcgtctg catctggcga agctgctgca ggttggcggc
    27901 aacatgctgc tgctcgacga accaaccaac gacctggata tcgaaaccct gcgcgcgctg
    27961 gaaaacgccc tgctggagtt cccgggctgt gcgatggtta tctcgcacga ccgttggttc
    28021 ctcgaccgta tcgccacgca catcctggac taccaggatg aaggtaaagt tgagttcttc
    28081 gaaggtaact ttactgagta cgaagagtac aagaaacgca cgctgggcgc agacgcactg
    28141 gagccgaagc gtatcaagta caagcgtatt gcgaagtaat gcgtaaaatg ccggatgcgg
    28201 cgtgaacgcc ttatccggcc tacaaaccaa gaaatttcaa tacgttgtga atctccaggc
    28261 ctgataagac gcggtaagcg tcgcatcagg cattgagcac cgaatgccgg atgcggcgtg
    28321 aacacctttt ccggtctaca acagccttag catccgcaat ttcgtagcgg gtcatccgtg
    28381 ctggttcttt caaaccttgt ttaatctcga cagcctcttc cagagaggtt ttcaactcat
    28441 caaaaaaact cattttatac ctcgcctttg agccgtttca tcgcggttat ccctgctccc
    28501 ccatcatctc ccgcaccagc tccacgcagc gaaggaaacg gctgtcataa tcgtcctctt
    28561 caacccgcac gaattcgata ttgttctctt ccagcatctc caccagcaag ttctggaact
    28621 ctttgcgatc caccgaactg ccgaggctgc gtaaaccatc cgccacccac ggcgtgttgt
    28681 tctccagcag gatcaccaga tcgaaacggt attcatcaat caacgcctgt acgaacggat
    28741 gctcacgccc ttcgtacttt ttgcagaacg cctgggtagt gacaaaatca gtgtcaataa
    28801 acgccacttt attggcatat ttcactgcaa aatcaatgta ttgtgcgtgg cccagcgcga
    28861 ttttatcgta atcggaatac tgcaatgcga tctcatcacc gccgaggtgt gaaaagacat
    28921 aatcgcgacc atattcccac gcactggtgg tattgaagat attggcaagt ttgtttacca
    28981 gggtggattt accgctcgac tcgccaccaa ggatcgccac ggtacgtaca aagaacggct
    29041 tcacttccgt aggaatatat tcccagtagc ggaacgggtt ttcgcggatc tgcgcaccgc
    29101 tgatactcat aaaggtacgt ttcggatcga ccagcaccgt atcgatcccc agatgttcca
    29161 tatactgtgg cgcatcggct tcttccgagg tgtagatcag gtccggctga atcccctttt
    29221 cagccataaa ctttttgatg ccgttgctcc acacatccca gccgtgcgga tacggctcca
    29281 tgccctcttc gttgaaagca tgaatgcgaa tatttttctg atatttaaaa gtttgtaata
    29341 accagcgcag acgatccggc accgtgggct gctgcgacat ggcgctgtct tcaaacaacg
    29401 cgcggtcgcg ggtatcgtca aaacccataa tgatatgcag ctcgtcaacc tggctacagg
    29461 cgcgctggat aaggtagata tgtccggtat gcagcgggta gaacttaccg aatacgacac
    29521 caatggtttt cttctgtcgg ggaaattcaa gccccaaaaa acggtgcaac gcctccagct
    29581 tttgcgcgct ggggctttta attttggcat tcagtaactg gcttaaatac cctttggtca
    29641 taccgctggc atcagctacc tgctgtagcg tgcagccctg ttgcttgatg gcagttttca
    29701 ggtaatcaaa tgacgacata tctccctccg tatctctcat tataagtcgt cgaacacgct
    29761 aagcgcgtcg gagagttttt taacgccaaa aatctgcatc ccttccggcg cttttttcgg
    29821 tacgttagcc gccggaacaa tcgcccggcg aaaaccgtgt ttcgccgctt cagagattcg
    29881 ttcctgaccg ctgggcaccg ggcggatctc ccctgccagc ccgacttcac caaacaccac
    29941 cagatcctgt ggcagcggtc tgtcacgcag gctggaaacc atcgccagca gtaacgctaa
    30001 gtcggcgctg gtttccgtta ccttcacgcc gccgaccacg ttcacaaaca catcctgatc
    30061 ggccatttgc agaccaccgt gacggtgcaa gacagccagc aggatcgcca gacggttttg
    30121 ctccagacct accgccacgc ggcgcggatt cgccatcatc gagtgatcga ccagcgcctg
    30181 gatctccacc agcaacggac gtgttccttc ccataccacc atcactgaac taccagaggt
    30241 cacttcatcg ccacggctta aaaagatggc ggaagggttg ctgacttcac gcagcccctg
    30301 ttcggtcatc gcgaagacgc ccagctcatt caccgcgccg aagcggtttt tatggctgcg
    30361 taaggtgcga aaacgggagt cggcatcgcc atccagaagc accgaacagt cgatacagtg
    30421 ttccagcact ttcgggccag ccagcgagcc atctttggtt acgtgcccca ccatgacaat
    30481 cgccacaccg cgcgttttgg cgaagcgtgt caaataagcc gccgtttcac gcacctgcgc
    30541 cacgctacca ggcgatgact gtacatccgc catatgcatc acctggatgg agtcaattac
    30601 catcagcttc ggttgctctt cttcggcaat caggcagatc tgctcgatgc tggtttccga
    30661 caacatattg agattgtcag tcggcaggcc aaggcgatga gcgcgcattg ccacctgttg
    30721 cagcgactct tcgccggtga catacagcgt tttcatctgc tgggccagtt tgcacagcgt
    30781 ttgcagcaac agcgtggatt tccccgcgcc tgggttaccg ccaatcagaa tggcacttcc
    30841 cggtaccacg ccgccgccta atacgcggtc gaactcttta aatccggtgg aaaaacgcgg
    30901 cagctcttca aggctgatgt cggagagttt ctggactttt gccaccccgg cgctaccggc
    30961 atagccactg agacgctcgt tacgcgccac cgttggcgac gcagcaagac gcacctcggt
    31021 gatggtgttc caggcatgac aggcactgca ctgcccctgc cagcgcggat aatcggcccc
    31081 gcattcatta caaacaaagg cgcgttttgg agcttttgcc acggtgtacc tcgttaatgc
    31141 tgtgccgccc gcaggatgac gggcaggcaa ttacttctga ttcaggctgc cagagaggat
    31201 gcagaatacc cccatcaggt cagcgtgacg gatggtgact tccgtctttt cattcacttt
    31261 tggcttggca tggtaggcaa tccccagccc tgccgctttg atcatcggca ggtcattggc
    31321 tccatcgcca atcgccacgg tctgcgccag cgggatttca tactcctgcg cgaggcgggt
    31381 cagagttttc gctttgtact gcgcgtcaac gatgtcgccg atcacattgc cggtaaattt
    31441 accgtccatg atctccagtt cattggctac cacggcggtc aggcgcagct tgtcgcgcag
    31501 gtattcagca aagaaagtaa agccgccgga ggcaatcgcc actttccagc ccagcgtttc
    31561 cagcttgagc accagctgcg ttaagcctgg catcagcggc agattttcac gcacctgttg
    31621 cagaatattg gcatcagcgc ctttcagcgt cgccacgcgg ctgcgcaggc tggcggtaaa
    31681 atcgagttcg ccgcgcatcg cccgttcggt tacctccgcc accatctcgc ccgttccggc
    31741 cagtttggca atttcatcaa tacattcaat ctggatggcg gtggaatcca tgtccatcac
    31801 cagcaaaccc ggcgtgcgca ggtgcgggat tttccccagc ggcgcgacat ccagttgcgc
    31861 ttcatgggcc aggcgcgtag cgcgcgcggt gagtgaacct gccagacgaa tcacctgata
    31921 atcttccacg caccaggcgg caacaatcac catcgccgcg cccagtttgc tctggtattg
    31981 ggtcaggcgt tgtttatcca gcccacgacc atacagcagc cagccgctac gacctgcgtg
    32041 gtaatccagt ggcatcactt catcaccact taatgaaaga ggcagacccg gccataaaga
    32101 gacatcttca ggcaggtcgc accaggtaat gttaggcatt aaggctcctg taaaatcgtt
    32161 cgaagcaggg aaaataacgc atgaggctac cttgtatcca ttgcttctgg caacattaag
    32221 tctcaaattt tcaaagggtg gaagatggct cgcacaaaac tgaaattccg gctgcatcgg
    32281 gcagtgattg tcctgttctg tcttgccttg ttagtggcgc tgatgcaggg agcgtcatgg
    32341 tttagtcaaa accaccagcg acaacgtaat ccacagctgg aagaactggc ccgcaccctg
    32401 gcgcgtcagg taacgctgaa cgttgcaccg ctgatgcgta ccgactcgcc ggatgaaaaa
    32461 cgcattcagg cgatcctcga tcagttaacg gatgaaagcc gtatcctcga cgcgggcgtg
    32521 tatgacgaac aaggcgatct tatcgcccgt tctggcgaaa gcgtcgaagt gcgcgaccgg
    32581 ctggcgctcg acggtaaaaa agcgggcggc tattttaacc agcagattgt cgaaccaatt
    32641 gccgggaaaa acggaccgct cggctatctg cgcctgacgc tcgacaccca tacgctcgcc
    32701 accgaagccc aacaggtgga taacaccact aacattttac gcctgatgtt gctgctttca
    32761 ctggcaatcg gcgtagtgct gacccgcacg ctgctacagg gtaaacgtac ccgctggcag
    32821 caatcgccct tcctgttaac cgccagcaaa ccggtgccgg aagaggaaga aagcgagaaa
    32881 aaagagtgac ccattactac aagaaaggaa atcgttatgt ccacattacg cctgctcatc
    32941 tctgactctt acgacccgtg gtttaacctg gcggtggagg agtgtatttt tcgccagatg
    33001 cccgccacgc agcgcgttct gtttctctgg cgcaatgccg acacggtagt gattggtcgc
    33061 gcgcagaacc cgtggaaaga gtgtaatacc cggcggatgg aagaagataa cgtccgcctg
    33121 gcacggcgca gtagcggtgg cggcgcggtg ttccacgatc tcggcaatac ctgctttacc
    33181 tttatggctg gcaagccgga gtacgataaa accatctcca cgtcgattgt gctcaatgcg
    33241 ctgaacgcgc ttggcgtcag cgccgaagcg tccgggcgta acgatctggt ggtgaaaacc
    33301 gccgaaggcg accgcaaagt ctcaggatcg gcctatcgcg aaaccaaaga tcgtggcttc
    33361 caccacggca ccttgctgct caatgccgac cttagccgcc tggcaaacta tctcaatccg
    33421 gataaaaaga aactggcggc gaaaggcatt acgtcggtac gttcccgcgt gaccaacctc
    33481 accgagctgt tgccggggat cacccatgag caggtttgcg aggccataac cgaggccttt
    33541 ttcgctcatt atggcgagcg tgtagaagcg gaaatcatct ccccggacaa aacgccagac
    33601 ttgccgaact tcgccgaaac ctttgcccgc cagagtagct gggaatggaa cttcggtcag
    33661 gctccggcat tctcgcatct gctggatgaa cgctttacct ggggcggcgt ggaactgcat
    33721 ttcgacgttg aaaaaggcca tatcacccgc gcccaggtgt ttaccgacag cctcaacccc
    33781 gcgccgctgg aagccctcgc cgggcgactg caaggctgcc tgtaccgcgc ggatatgctg
    33841 caacaagagt gcgaagcgct gttggttgac ttcccggacc aggaaaaaga gctacgggag
    33901 ttgtcgacgt ggatagcggg ggcggtaagg taactcgctg attaaaatac caaaggaagg
    33961 gaatatgatc gatctggaaa accaggagcg ggagattatc aatttaatgt taagccagcg
    34021 tatttcctgg ctagccgccg tgcgtatcag gcataaatta tcgcttgctg aagtaagtaa
    34081 aatgttaggt atctcgatta attctctaaa atagatcgaa aagacggaac ggtttagctc
    34141 aaacatcaaa agcaaaatgg cagaaattta tggttgtcca ccagagttgc tgatatgccc
    34201 ttcctggatg acggctgaac ataaatgaat agattcgtga atagatactt gaatagattt
    34261 tattttctat ccatatgaaa aataatagta aatctataaa tcagttgcta ttgatgaata
    34321 gatactaaaa agccggagca gtctcccact ccggcttcac acgacaatcg cctttcagcg
    34381 aaacacaatt actctttatc gcccagcaga acggattcca gtgcgatttt gatcatgtcg
    34441 ttgaaggtgg tctgacgctc agcggcagtg gtctgctcgt gagtgcggat gtggtcagac
    34501 acggtacaga tggtcagggc tttcgcgcca aattctgcag cgacgccgta gataccagcc
    34561 gcttccattt ccacgccgag gatgccgtat ttttccatca cgtcgaacat ttcgccgtcc
    34621 ggagagtaga acaggtcagc ggagaacagg ttaccaacgc gagcatcaat gcccagtgct
    34681 ttagccgcgt ctaccgcgtt acgcaccatg tcaaagtcag cgatagcggc aaagtcatga
    34741 tctttaaaac ggatgcggtt aactttggaa tcggtgcagg cacccatacc gataacgacg
    34801 tcgcgcagtt ttacgtgcgg cagaactgcg ccacaggaac ccacgcggat aattttcttc
    34861 acgccgaaat cggtgatcag ttctttggtg tagatggagc aggacgggat acccataccg
    34921 tgacccatta cggaaatttt gcggcctttg taagtaccgg tgaagcccag cataccgcga
    34981 acgttgttca cttcacgggc atcttcaagg aaagtttcag caatatactt cgcacgcagc
    35041 gggtcgcctg gcatcaaaac tacgtcagcg aaatcgccca tttctgcatt aatgtgtggg
    35101 gtagccattg ttttatcctt atcaacatgt tttcaccctc tccctgaggg agagggccgg
    35161 ggtgagggca tcaagccgca cccattatca gaacatggct ttgccatatt ccatatcaga
    35221 agtaccaaaa tattttgcca gagtctggcc gatatccgcg aaggtttcac gatgacccag
    35281 tgagcccggt tttactttcg ggccgtatac cagtaccgga atgtgttcac gcgtgtggtc
    35341 agtaccggtc caggtcggat cgcaaccgtg gtcagcggtg aggatcagga tgtcgtcatc
    35401 gcgcagcaga gacatcagct ccggcagacg gcggtcgaac agttccagac ccgcggcata
    35461 accggcgacg tcgcgacggt ggccccagga agagtcgaag tcaacgaagt tggtgaagac
    35521 gatggtgtta tcacccgctt ctttcatctc tttgatggtg gcgtcaaaca gcgcgtccag
    35581 gccagtcgct ttcacttttt tggtgatacc gcagttggcg tagatgtctg caattttacc
    35641 gacagaaacc acctggccgt gtttttcatc aaccagtttc tgcagcacgg tcggtgctgg
    35701 cggctcaaca gccaggtcgt gacggttacc ggtacgctgg aagttaccgg ctttgtcacc
    35761 gataaacgga cgagcgataa cacgtccgat gttgtagccg ccgttggtca gctcttcacg
    35821 ggcgatttcg cacagttcgt agagtttatc caggccaaag gtttcttcat ggcaggcaat
    35881 ctggaacacg gagtcagcgg aggtatagaa aatcggcttg ccggttttca tgtgctcttc
    35941 gcccagttga tccagaatga ccgtaccgga agagtggcag ttaccgaggt aacccggcag
    36001 attagcgcgt tcgaccagtt tatccagcag ctcttgcggg aagctgtttt cgtgatcgga
    36061 gaaatatccc cactcaaaca gaaccgggac accggcgatt tcccagtgac cagacggggt
    36121 atctttaccg gatgacattt cgtgcgccca tgcgtacgcg ccgataactt cagcgttgcc
    36181 gtccattccc gccggaatga aaccggtaga accttcgtgt gctttcgcca gccccagacg
    36241 ggtcagattt ggcagattga gcgggccttt acgaccgtta tcagcttcgc ctttggcaca
    36301 agcttctgcg atatgaccca gggtgtcagc cccgacgtca ccaaagcgtt ctgcatcttc
    36361 tgtagcgccg atgccgaatg agtccagcac cataataaat gcacgtttca tatgttctcc
    36421 gtactcagtg cttcaaattt aaatgatcag atcagtatac cgttattcgc tgatacggcg
    36481 atagacagtt ggtgtgcttt ccggtgcttt atcggcaagt ttaattgccg ctttcaccgc
    36541 tttcgccgct tcctgccagc tgttttcgtc tttcgcgtgg ataaccgcca gcggacgctg
    36601 accgtctacc tggtcgccca gacgtgccat atcagtaaag ccgacgctgt aatcgatggt
    36661 gtcagatgcc tgacggcgtc cgccgcccat tgcaaccact gccatcccca gcgcgcgggt
    36721 atccatttca ctgacaaaac cttcggtatc agcatagact gctttcgtca gcatcgctgt
    36781 cggcagatac ttcgcgtagt tctcaacgaa gtcggttggg cctttttgtg ccgctaccat
    36841 acgaccaaag acttctgccg ctttaccgtt gtccagcacc gcctgcaatt tcgcgcgcgc
    36901 ttcggcgtca tctttcgcca gtttgccgga gatcagcatc tccacgcaca gcgccatcgt
    36961 gacatcaaac agacgcgggt tacgatattc acccgtcagg aactgcaccg cttcacgaac
    37021 ttcaaccgcg ttacctgcac tggaggccag tacctgattc atatcggtga gcagcgcggt
    37081 ggtgcgcacg ccagcgccgt tagccacgcc aacaatcgct tcggcaaggg cttcagagag
    37141 ttcgtaggtc ggcataaacg cgccgctacc cactttcacg tccatcacca gcgcatccag
    37201 accttccgcc agtttcttcg ccaggatcga ggcagtgatc agcgggatgg agtccacggt
    37261 tgcggtaata tcacgggtcg cgtagaaacg tttatccgcc ggagccagtg agctggtctg
    37321 gccgataatc gctacgccga cgtctttaat aatttcgcgg aaacggttgt catccgggaa
    37381 aatgtcgaag ccagggatgg attccagttt gtcgagcgta ccgccagtat gaccgaggcc
    37441 gcgaccggag atcatcggaa tatagccgcc gcaggctgcg accatcggcc ccaacatcag
    37501 cgaagtcaca tcgccgacgc cgccggtgga gtgtttatca acaatcgggc cattcagatg
    37561 caggcttttc cagtcgagaa cggttcctga atctcgcatc gccatggtca gcgagacacg
    37621 ctcaggcatt gtcatatcgt ggaagaaaat ggtcatcgcg agggcggcaa tctgcccttc
    37681 ggagatagtg ttgtcgcgaa taccgttgat aaagaaacga atttcttcat cgctcagcgc
    37741 atgaccatca cgttttttac gaataatttc ttgtgcgaga aacaaggtaa cctcccgagg
    37801 aaaagagtat gaggcggctt ttgccggatg cgtctacgcc ttatccggcc tacgggtaga
    37861 tacgtttcgt aggcctgata agcgcagcgc atcaggcgta aagcatctta cttagtagct
    37921 gctggcgctc ttaccgtcac cgtggcccag cgctttcaac aggcttgcca gcaggctgga
    37981 agcaccaaag cggtagtgac gcgcatctgc ccagtcagca ccgaacagtt catctgcgat
    38041 ggcgagatat ttctgcgcat cttccgcagt acgcacgccg cccgctggtt tgaaaccaac
    38101 ggttttttct acgcccatat cacggatcac ttccatcatg atgcgcgcgc tttccggcgt
    38161 cgcgttcaca gccactttac cggtagaggt tttgatgaag tccgcacccg ctttgatgga
    38221 gatttcagac gctttacgga tcagcgcttc gtctttcagt tcgccggttt cgatgatcac
    38281 tttcagcagt acattcgctg ccgcgcaagc ctctttacag gctttcacca ggtcaaaacc
    38341 aacctgctcg ttacccgcca tcagcgcgcg gtacgggaac acaacgtcaa cttcatcagc
    38401 accgtaggcg attgccgcac gggtttctgc cagcgcgatt tcgatgtcat cgttaccgtg
    38461 tgggaagttg gttaccgtag cgattcggat ttccggggtg ccctgctctt tcagcgtttt
    38521 gcgagcaatc gggataaagc gaggatagat acagatagcg gcggtattgc cgaccggagt
    38581 tttggcctga tgacacagag caattacttt ctcgtcggtg tcgtcgtcat tcagggtggt
    38641 caggtccatc aatttcagtg cacgcaggct gcttgctttc agatcagtca tttcattctc
    38701 ctggcttgtt gccaataaaa ttcaccttgc gagtttgtta gtattctaac atctactccg
    38761 caacacactt cgatatacat cacaattaag gaaatctact tacaagtttg catcactgta
    38821 atgcgatctg gttcaaataa ttcactttca aatgaatgcg tcagtggtgg caaacgcatc
    38881 aggatcaaag tgaacatcac gaaacttctt acaatggcgc atcaccttcg gcataaaagg
    38941 aaaagaagat gcccacttct catgaaaatg cactgcaaca acgttgccag caaattgtca
    39001 ccagcccagt gcttagcccg gagcagaagc gccattttct ggctctggaa gcagaaaaca
    39061 atctgcctta tccgcagctt cctgccgaag cccgccgcgc gctggatgag ggtgtaatct
    39121 gcgatatgtt tgaaggtcat gcgccgtaca aaccgcgcta tgtcttaccc gattacgccc
    39181 gttttctggc gaacggttcc gaatggctgg agctggaagg cgcgaaagat cttgatgacg
    39241 cactctctct gctgaccatt ctttaccacc acgtaccgtc ggtcacatcg atgccggtct
    39301 acctggggca actggatgcg ttgttgcaac cgtatgttag aattctaaca caagacgaga
    39361 tcgatgttcg aataaaacgt ttctggcgtt acctcgacag aaccctgcca gacgccttta
    39421 tgcacgccaa tatcggcccg tctgattcgc ccattacccg cgcgatctta cgtgcagacg
    39481 cagagttgaa gcaggtttca ccgaacctga cctttatcta cgatcctgaa atcacccctg
    39541 atgacctgct gctggaagtg gcgaagaaca tctgtgaatg tagcaaaccg cacatcgcca
    39601 acggtccggt gcatgataaa attttcacaa aagggggcta cgggattgtg agctgttaca
    39661 actcactgcc gctggcgggt ggtggcagca cgctggtacg ccttaacctg aaagccattg
    39721 ccgagcgcag cgaatcgctg gatgacttct ttacgcgcac tctaccgcac tattgccagc
    39781 agcagatcgc catcatcgat gcgcggtgtg aattcctcta tcaacaatca cacttctttg
    39841 agaatagctt cctggtgaaa gaagggctga ttaaccctga acgttttgtg ccaatgtttg
    39901 gcatgtatgg gctggcggaa gcggttaact tgctgtgtga gaaagaaggg attgccgcac
    39961 gttacggtaa agaagccgcc gcaaatgaag tgggttatcg catcagcgcg caactggcgg
    40021 agtttgtcgc caataccccc gtgaaatatg gatggcaaaa acgcgccatg ttacacgcac
    40081 agtcggggat cagttccgat atcggcacca cgccgggcgc gcgtttaccc tatggcgatg
    40141 agccagatcc gatcacccat ctgcaaactg tcgccccgca tcatgcttat tattattccg
    40201 gcatcagcga cattctgacg ctcgacgaaa ccatcaaacg taatccgcag gcgctggtac
    40261 agctttgcct cggtgccttt aaagccggaa tgcgtgaatt taccgccaat gtcagcggta
    40321 acgatctggt tcgcgttacc ggttatatgg tgcgtttgtc ggatttagaa aaatatcgcg
    40381 ccgaaggttc acgcaccaac accacctggc tgggcgaaga agccgcacgc aacactcgta
    40441 ttctggaacg ccagccgcgc gtgataagcc atgaacagca gatgcgcttt agtcagtaag
    40501 attatcccct tctcctgcgt tgacgggcca ggcagtcgtc tggctctgtt tttgcagggc
    40561 tgcaatctgc gctgcaaaaa ctgtcacaat ccgtggacga tggggcgctg taatcattgc
    40621 ggagagtgcg tgccacagtg tccgcatcag gcgttgcaga ttgttgacgg caaagtggtg
    40681 tggaacgctg cggtctgcga gcagtgtgat acctgcctga agaggtgtcc gcaacatgcc
    40741 acgccgatgg cgcaatccat gagcgtggac gaagtgctta gccatgtccg caaagcggtg
    40801 ctgtttattg aagggataac ggtaagcggc ggcgaagcca cgacccaact gccgtttgta
    40861 gtggcgctgt ttactgctat caaaaacgat ccgcaactgc gccatctcac ctgtctggtg
    40921 gacagtaacg gcatgttgag cgaaaccggc tgggaaaaat tactcccggt gtgtgacggc
    40981 gcaatgctcg atctcaaagc atggggtagc gaatgtcatc aacaattaac cggacgcgat
    41041 aatcagcaga ttaagcgcag catctgtttg ctggcagagc gcggcaagct ggcggaactg
    41101 cgtttgctgg taatccctgg ccaggtggat tatttgcaac acatcgaaga actggcggcg
    41161 tttatcaagg gacttggcga tgttccggta cgcctgaacg cgtttcatgc ccacggcgtg
    41221 tatggcgagg cgcaaagctg ggcgagcgcc acgccggaag acgttgagcc gttggctgat
    41281 gcattaaagg tgcgcggggt gggccggttg atatttccgg cgctgtattt gtgacatgcc
    41341 ggatgcggcc tacggttcgg cacagacttg taggcatgat aagacgcgtc cagcgtcgca
    41401 tcaggcattg tgcgccaact gccggatgcg gcgtgaacgc cttatccggc ctacggttcg
    41461 gcacaaacct gtaggcctga taagacgcga caagcgtcgc atcaggcatt atgcgccgac
    41521 tgccggatgc ggcgtgaacg ccttatccgg cctacggttc ggcacagact tgtaggcatg
    41581 ataagacgcg acaagcgtcg catcaggcat tgtgcgccaa ctgccggatg cggcgtaaac
    41641 gccttatccg gcctacggtt cggcacagat ttgtaggcat gataagacgc gtcaagcgtc
    41701 gcatcaggca ttgtgtgccg actgccggat gcggcgtgaa cgccttatcc ggcctacggt
    41761 tcggcacaaa cctgtaggca tgataagacg cgacaagcgt cgcatcaggc attatgcgcc
    41821 gactgccgga tgctgcctac gaagggtaaa ctacccacta acgctaaaca acgcatacgt
    41881 attattaagc aacacttcgg caatctcatc ttctggttcc gggcgcaact cgcaaagcac
    41941 atcaaacacc cgcacagcct gttccggtcg gttaggctgc ccctgaaagc cgttgagcgg
    42001 catatccggc gcgtcggttt ccagcaacaa cgatgccagc ggtaattttg cgatgacatc
    42061 gcgggtttta ctggcgcgtg gataggtgat agtaccgcct acgccgattt tgtagcccag
    42121 ctgtacaaac cgttcagcct gttgctggct gccagaaaat ccgtggacaa caccagcacg
    42181 cggcaaatcg tggcgtttaa gatgcatcgc cagtttgtcg tgtgtgcgcc gtgaatgcag
    42241 gatcaccggc agatcgtagc gtttcgccag tttcagttgt tcgtcgagta accactgctg
    42301 cctctcaaat tgcggatcgt cgccgaagag atccagaccg atctccccca ccgccaccac
    42361 cttcgccgga cgcctttcca gcgcctgctg tagctgatca agagacacat cgctatgttt
    42421 ttccaacatc cccggatgca accccaatgc ggcatacagc ggttgatatt tttccgctaa
    42481 cgcctgcacg cgggcaaaat tttccgcctc tgtcgccgga acaatgatct tgcctacgcc
    42541 cgcttgtgcc gcgcgttgca ggctggcctc ttcatcgcca ctaaacggcg ggaaatcaaa
    42601 atggcagtgg gtatcgataa aacggcaaat caagccagat cctcattgtt aaatgtcggg
    42661 tcgttcgcct gcggagcatc gctcacttcg gcaaccagcg tatcgttggc gactggcgca
    42721 ggcggaataa cgatcgattc cggcgtcacc actggcacca gatggcgggt aagcggcgct
    42781 ttttcagtta atagcttgcc aaccgtggcg aggaaataac gaccgcataa acgcccaagt
    42841 ttatagtctt cacgcagcgc cggaacccga ctgccaagcg cgatactatg taatggcttc
    42901 ggcggataaa tttcgaatat ccgcagcttg cccggtggtt tctcaataaa ttgctgaatg
    42961 tcacgatagc tggtttcatg atgctgcacc agattgacca gcggctgcag gctactgtca
    43021 cccagccagc gttccatgcg tttgaaccac tgcggcgtgt agtacatttg tgacggcaca
    43081 gtgcggatga cgaccaacgt tttagcgccc tgccttgccg cctctttaac cggaatcgca
    43141 tcactgatcc cgccatccag gtagttaatg ccttccagcg acactccgct acgataaaag
    43201 ccaggtatcg cactggaggc gcgaatcaca tccagccagt tttgtttggt tggtaaaaag
    43261 taattcggcg cgtagtcatc ctgacgacag gcgcacatat aaaacgattt gccgctgtca
    43321 aacaaccgcg cggcggtatc catttgcaac ggcatctggc ttgcggtggc ctccaccagc
    43381 cagtcgagat cgataagatt tcctccacgg acaaagcgca atggatcgaa aaattcgcgt
    43441 tttgtggtat agcgcatgat gactttgcgc gcgtaaccgg gctgattgca gataaacgcc
    43501 gagaggttct gcgccccggc agatgtgccg agataaagat cgaaaggatt aaactgcgcg
    43561 cgcataaact catccagcac gccagccgtg aaaattccac gctgtccgcc gccttcgcac
    43621 accagagcta ttcgtccagg ctggaacggc cttagcgaca acggcgcaat attaccaagc
    43681 gttacaggta ttcgctgccc cacctctgcc ttcctgtttt tgttgtgaaa gaatgacaaa
    43741 gtaacgcaat ttattattcg ctaaaaccgc aaaagccagt ccgctggact ggctttggat
    43801 aaaattttct taatggtctg aaatctaggg tcgttttcgg cccatgaaca aactcaccag
    43861 gaacagaata atcccgacga caaagacaat tttagctgcg cctgcagcgg taccggccag
    43921 accaccaaac ccaagtgcgg cggcgattaa cgcgataacc agaaatatga tgccccaacg
    43981 aaacataagc gtctccttta ccatagttaa tgtcaccgct tgatatgagc gtgaaaatca
    44041 ctcaatgcga tatttttagt gtggtgcaca tcgcgcctcc cgacaaagtt cgggaggacg
    44101 aattacgacg aattacttag ttttcagatc atttttaacg cttttcacac catctaccgc
    44161 tttggcgata ctttcagcac ggtcactttg tgcctgagaa tctacggtac cggagagctg
    44221 aaccacgcca tcggtggttt caactttcac atgacgggaa gggacgatat cgtccgccag
    44281 cagtttggct ttgatttcac tggtggtggc ggtgtcaccc gcgtagccct tcaccgagcc
    44341 ttctttagcg tcgcgaacgt gcagtttgtc gctgacagag gtcacccctt caacgccttt
    44401 cgccactttc actgcctctt cggcctgagc ctggctttca acaaaaccgc tcagggtcac
    44461 gactttttga tcggttttta cagagatatc ggtgctcttg atgttgtcat gatccaccag
    44521 ggccgccttc actttcgcgg tgatggcgct gtcatccatg aaattaccga ctttattcat
    44581 agagctatcg actttttgcc ctgcgctttc attggtagtc tgtgcgttgt tttccgcgta
    44641 ggcagagccg gtcgcgacgg cagaggtcaa cattacagcc agcagagttt tcgaaatctt
    44701 cagtcttgtc atagtcatcg atttattcct gtatgtttgc tcgtaatttg agcctggcaa
    44761 cacgaggttg cattgctgaa tagggagaga cttcaccctc tacagaagtc aatggtcgcc
    44821 atcacaaaag cgatgggtga tgaataacga ccattacagc ctctgaatca gttattaata
    44881 tcggtagaat gacaatcgac ggctttagat actgatatct acgcattgaa cggtatttaa
    44941 cgccgtcaga aatgtcatta ctttgttaaa tatagatcac aattttgaaa ccgctcggga
    45001 tatcagcgaa aacataagca aaagtgaatg ttttaagaac attccgtaag cggctaataa
    45061 ggaagggaaa ttgacagggc gcagcggcta ccgcgccctg gaggcaagaa ttaatgctcg
    45121 cgggtctggt ggaactgaac gtcgggataa cgttcctgcg ccaggcgcag gttgaccatg
    45181 ctggtagcga tgtaagcgag gttatcgccg ccatcaagcg ccagttggct ttcgttctta
    45241 cgcttgaact cttcgaattt cttcgcgtcc gcacattcta cccagcgggc agtggcaacg
    45301 ttgactgatt catatactgc ttcaacgttg tattcgctct tcaggcgcga taccaccaca
    45361 tcaaactgca gcacaccaac agcaccaacg atcaaatcgt tgttggagat cggacggaac
    45421 acctgcaccg cgccctcttc ggaaagctgt accagccctt tgagcagctg tttttgcttc
    45481 agcggatctt tcaggcggat acgacggaac agttctggtg cgaagttcgg aataccggtg
    45541 aacttcatca tctcaccctg ggtaaaggtg tcgccgatct gaatagtgcc gtggttgtgc
    45601 aggccgagga tatcgcccgg atacgcttct tcaacgtgcg aacggtcgcc cgccataaag
    45661 gtcagcgcgt cggagataac cacatctttc gcagtacgca cctggcgcag cttcatgcct
    45721 ttttcatatt taccggatac tacgcgcata aacgccacgc ggtcgcggtg tttcgggtcc
    45781 atgttggcct gaattttaaa tacgaagccg gtaaatttgt cttcgctcgc ctctacggta
    45841 cgggtatcag tctgacgcgg catcggcgca ggggcccact ccaccaggcc atccagcata
    45901 tgatcaacgc cgaagttacc cagcgcagta ccgaagaata ccggagtgat ttcgcccgca
    45961 aggaacaatt ctttgtcgaa ctcgttagac gcgcctttca ccagttccag ttcgtcacgt
    46021 agctgctgtg ccagatcttc accaaccgca gcgtcgagat ccgggttatt cagcccttta
    46081 acaatacgga cttcctgaat cgtgtggcct ttaccgctct gatagagata ggtttcgtct
    46141 ttataaaggt ggtaaacgcc tttaaacagc ttgccgcagc caatcggcca ggtgatcggt
    46201 gcgcagccga ttttcagctc gttctcaact tcatcgagca gttccatcgg gtcgcggata
    46261 tcacggtcaa gtttgttcat aaaggtgagg atcggcgtgt cgcgcagacg ggtaacttcc
    46321 atcagcttac gggtacgatc ttcaacacct tttgcggcgt cgataaccat caggcagcag
    46381 tccaccgccg tcagggtacg ataggtatct tccgagaagt cttcgtgccc cggggtgtcg
    46441 agcaggttaa ccaggcaatc gtgatacgga aactgcatca cagacgtagt aatggagatc
    46501 ccacgctgct tttccatctc catccagtcc gacttagcgt gctggttgga accacggcct
    46561 tttactgtac cggcggtctg aatggcctgt ccgaacagca gcaccttctc ggtgatggta
    46621 gtcttaccgg cgtccgggtg agaaataatg gcaaaagtgc ggcgcttcgc cacctcttgc
    46681 aaataaggag acaacgtcat aattctttct tcttgagtaa gcggcatcgc gccgcgcttg
    46741 ttgaaaacga aaaattgcgg ctattttacc catcaacggg ggggaggcaa tcagtgttta
    46801 cacaggagct gctccagttc gtgcaacgat gaaacggtcc aggtgggcgc gatgccttct
    46861 ggttgctcgc gatggtgcgc attcagccag caggtcgcaa gcccggcgtt gatgccaccg
    46921 agaatatcgg actcagcagt gtcgccaacc atcagcacgc gtgaacggtc aggattgccc
    46981 gcctgttcca gcgcataatc gaaaattttc ttattcggtt tagcaacgcc aacttcttcg
    47041 gaaatcacca gcaaatcgaa gtaatcacgc aggcccgtac gttccagacg cacttgctgc
    47101 aaggcgctaa agccgttggt gatgatgccg attttggcgt tgccacgaat ggcgttaagc
    47161 agagaaaccg cgcccggcag cggcgtacag atttccgcca tcgcattaat aaaggcttcg
    47221 ttgagtttac ccggctcgac gttcagccgt tcggcccagc tctcaaaccg cccgtgctga
    47281 agctgtaatg aagtgatcgc gccgttttga taatccaccc acagtggctt gttaacggcc
    47341 tgatagtcct gaaaatcttc agcggtaaag gtgacgctgt aatcaagaaa catccgctgc
    47401 aggccggtga atgagtcaaa ggtaaacagc gtttcatcgg catcaaagaa aatccagtcc
    47461 cacttcatta ttccaccttg tattacatac tgattggcaa cgccatgatg atggcgtctt
    47521 cgcgaccgtc cgtggtgggg tagtaattgc ggcgaatcgt cgcctcgtta aagcctaaac
    47581 tttcgtacag ggcaatggcg gcagcgtttg aggcacggac ttccagccat agcgtcgcca
    47641 caccgcgttt ttccagttcg tcgatcagat gttccagcag cgcccttccc aatccctgac
    47701 gctgatagtc gggatcgacc gcaatattga acaatgtagc ttcatccagc accacttgcg
    47761 taatcgcaaa cgccgccatt ttgccgtttt gcgttaactg aaagttgaga taacgctcgc
    47821 cctggttgct ggcaaaggtt ttttcactcc acggaaaggc gtgggcgcgt tgttcaatgt
    47881 ggtaagccgc cggtaaatca gtcgtttcga gggaagaaat cgtgttcata tgtgcaaatc
    47941 tgttgccata acgcggcgcg tgccgttggg tttgcccgta attcggtgag cgccggtgat
    48001 gccacctgag cgccttccag tgatagcggt tcgtcagtac ccaaccgcca gctgttgcag
    48061 cgactgcctt gcggcagcat cgcgattttt tctggcgtca gttgcagcac ctggtcgggg
    48121 ctgacggtta atgcgcgcag aacatcgctc actaaaggat cagtcagggc gggaagatcg
    48181 tttgccacca tcaccagacg gacgtgtgcc gggatcgcaa tggcaatctc cccctgcaac
    48241 gcgccagggc gacgcagcga ccactgggta atgcccagtt gctgtaactg ccagtctcgt
    48301 cgggatgtca tagcgaatcg ctcctgttgt caggggcgca aatatagcaa attcgtcgat
    48361 accgcgccaa catatggcta taatcgccgc cagtatcaat tgaggagcat tccatgtctg
    48421 catttacccc ggcaagtgaa gtcttgctgc gtcacagtga tgatttcgaa caaagccgta
    48481 ttctgtttgc cggagactta caggatgacc tgcccgcgcg tttagatacc gcggccagcc
    48541 gtgctcatac ccagcaattc caccactggc aggtgttaag ccgccagatg ggggataacg
    48601 cccgttttag tctggtcgcc acggcggatg acgtcgcaga ttgcgatacg ctgatttact
    48661 actggccgaa gaacaaaccg gaagcccagt tccagttgat gaatttactt tctctgctgc
    48721 cagtggggac agatattttt gtcgttggcg agaaccgcag cggcgtgcgc agcgccgagc
    48781 agatgctggc agattatgcg ccgttgaata aagtcgacag cgctcgtcgc tgtggcctct
    48841 attttggtcg tctggaaaaa cagccggtat ttgatgccga taaattctgg ggcgaataca
    48901 gcgtcgatgg cctgacggtc aaaacgctgc ctggcgtgtt tagccgcgac ggtctggatg
    48961 tcggtagcca gttgctgctc tcgacgttaa ctccgcacac gaaaggtaaa gtgctggatg
    49021 tcggctgtgg cgcgggtgtg ctttcagttg cctttgcgcg ccattcgccg aaaatccgtc
    49081 tcaccttgtg cgatgtctct gccccggcgg tagaagccag ccgcgcgacg cttgcagcca
    49141 acggtgttga aggtgaagtc tttgccagca acgtcttttc cgaggtgaaa ggtcgttttg
    49201 atatgatcat ctccaacccg ccgttccacg atgggatgca aaccagcctg gatgcggcgc
    49261 aaacgctgat tcgcggtgcg gtgcgtcatc ttaatagcgg cggcgagctg cgaattgtag
    49321 cgaacgcctt cctgccttat ccggacgtgc tggatgagac atttggcttc catgaagtta
    49381 tcgcgcaaac cgggcgcttc aaggtgtatc gcgccattat gacccgccag gcgaagaaag
    49441 gttaagtatc ccgccgcaag ccttgccgga tgcggcgtaa acgccttatc cgacatacca
    49501 aacctgcacg ttagcccttg taggccagat aagacgcgcc agcgtcgcat ctggcatctg
    49561 cccccgaatg ccgtgtcgga tgcggcgtga acgccttatc cgacctacaa acgaattatc
    49621 cacaatccgc tgatggccat ttttccagca attacacctc cggcgataat taactattga
    49681 cgaaaagctg aaaaccacta gaatgcgcct ccgtggtagc aattcttttt aagaattgat
    49741 ggtatgcgaa ggtggcggaa ttggtagacg cgctagcttc aggtgttagt gtccttacgg
    49801 acgtgggggt tcaagtcccc cccctcgcac caattatctt tacttccttt cttgtttctt
    49861 ccttgatttt tcatccctga ttcaaattca ttagcatcag catgatacca gcactaagcg
    49921 ccaggcacga tggtagcaaa atgtaatgcc gtaactgttt gtgatacagc atcaccggcg
    49981 tcaatatcaa tcccatcaga atgacaatcc gccactgatc cggcgataaa tccgcataca
    50041 tcagccctgc aatcagcaat cccggcagca acactcccca gccactgccc agcgtacgtt
    50101 gcaacatggt ttcatctctt tcattgataa tgataaccga tatcatatga taatttttat
    50161 catttgcaag ccagagaaat cccttgctat cgggtaaacc tatcgctagg attagcaatc
    50221 attatcattt agattactat cacgattatg gcctatcgtt ccgcaccgct ctatgaagat
    50281 atcatctggc gaacgcatct ccagccacag gatgctgggc ttgcacaagc cgtacgtgcg
    50341 acgatcgccg aacatcgtga acatttgctg gagtttatcc gcctggatga acccgctccg
    50401 cttaacgcca tgacgctggc gcaatggtca tcaccgaatg cgctaagttc tctactcgcg
    50461 gtctattccg atcatatcta tcgcaaccaa ccaacgatga tccgcgagaa caaaccgctg
    50521 atctcactat gggcacaatg gtatatcggc ctgatggtgc caccattaat gctggcgcta
    50581 ctgacgcagg aaaaagcatt agatgtgtcg ccggaacatt tccatgctga gtttcacgaa
    50641 accggccgtg ccgcctgttt ctgggtcgat gtgtgtgaag ataaaaacgc aacaccacat
    50701 tcgccgcagc agcgaatgga aacgttaatc agccaggcgc tggttccggt tgtgcaggca
    50761 ctagaagcga ccggagagat aaacggcaaa cttatctgga gtaataccgg ttatttgatc
    50821 aactggtatc tcactgagat gaagcaactg ctcggcgagg cgacggttga atcgctgcgc
    50881 catgccatct tttttgagaa aacgctcacg aacggtgaag ataatccact ctggcgtacc
    50941 gtggtactgc gcgacggcct gctggtgcgc cgcacttgct gccagcgtta tcgcttaccg
    51001 gatgtgcagc aatgtggcga ttgtacgctg aaatgaaagc actgccgggg aagtaaaccc
    51061 ggcatcatgc ggattaatag ggatgcaaca cattacttgc ttcgcaatgc cgcatacata
    51121 acagaatatc tgcggcctcc aacaatcctg catcagaact gacgcccagt ttcgacatca
    51181 cattaaattt atgcgcgcgg atcgttttga tattgcgttt aagctgctcg gcaatttgtg
    51241 tcattgagta gccacgcgac ataaagcgca atatttctct ctccgtcggg cttagcgtcc
    51301 ggctttggtt aatgtaccac tgattgttca gtcggtcggt cgcctgacgt acaccattta
    51361 atgacaaaaa gagttcctga tgaaaaatct ccagcgttga cgctttactt aatacaccgt
    51421 ccagcggtga tggcgacaat gaaccaatca gccgagcttc aatatcatca tccgcaataa
    51481 ctaaacgccg ggtacgcgga aacttaatcg ccagttcagt caggcaagat aatccctctc
    51541 tgcgctcact tctcatggca gaaaaagaaa aaatgaccgc cgcaaacgag atccgcgata
    51601 tggcatcctg aaatgactcc tgactggtat aggtatggag cttataaggg gtgcccgcaa
    51661 actttctgaa taaactctca ataccgatac tactcatgac gcatttttct atgagtgcga
    51721 catttctctt cttaattcgg ctgtgttcca ttctgcggca tctccataaa cagaaggcaa
    51781 gttaagttct cttgcaccct gcgcgctatt tatccatgca tacatttcag cgttgctgtg
    51841 aattgccagt cgacgcatcg cactgttttt ttgggcgctg atagttttat tacttttctt
    51901 aagcaatgaa gctatctggt tgatgcccca tcctttacct aatagccgca gtaccttgcg
    51961 ctctgaaaga gtgagaatga cggagcgata gctaaaatca tgagtttcag tcattgccgg
    52021 ggaggtcagc atggcgctga tacgctctgc gtgcgtattg ccggaacgta cggtcttgac
    52081 cagattctca atgggttcaa catcagacaa taacgtcgcc gtagggcaca tgagcagttc
    52141 tactgcctgg gaataccagg agcgtgacac catgaaaacc cagtgaattt cccgatattg
    52201 tgagattaaa gaataataat gttcacaaac agaacgtgga tcttcacttt caccggctaa
    52261 atcagcaatg actaatccgg aacgacgtaa ttgtaataag gtaaggtcct ccgcagaggc
    52321 gctggatatt atttcatatt cagggaagtg agtcctcatg acctctttta accctgcttg
    52381 cataacaggt attttactga taacaattcc atttttgcag catcctggca acatatttcc
    52441 tccacatcca ctgtctaaaa attatgatgg tttattcagg atattcattc cttaaatgtt
    52501 tccagcaaat taatagatta agcgaataaa ttatccttag cattcacttt catatcagca
    52561 tactcctgct gcacaacaac tccactgcat gtgtcagaag gttagcatca aatgataacc
    52621 tggtgaaata gcctggagac atttaaaata tctacattaa gttgttagga atacttaatg
    52681 aaaaacagaa atcacattca tttaatttat aattaaatga tatcccttcc cgcagaatga
    52741 aaaatcacac aaccaatatt tattcaatga aatctgatgg ttttaacttg ttaacattaa
    52801 aaaacgtgcc cggttatcta ttattctggt tcgtaaagga caaacaataa attcattatg
    52861 gtgataatat tcatgtgata gtttgtttgc gacgagagat aattcgcttt ttatcaccga
    52921 gcttgtcccg ataaccagga ttaatcagcg caattttgat cttaacctac cgcaaaacaa
    52981 ccgtgcttca tgatacaaat ggattctcat tatctgaaca atacgcagca cgtctatgac
    53041 aaagggcgag ttatgcaaac tgagcaacag cgagccgtaa cacggctttg tatccagtgt
    53101 ggattatttc ttttgcaaca tggtgcggaa agcgcgttgg ttgatgagct ttcctcacga
    53161 ctgggtcggg cgttggggat ggacagcgtc gaaagttcta tctcttcgaa cgccatagtg
    53221 ctgacaacca ttaaagatgg gcaatgcctg acatcgacac gtaaaaatca cgatcgcggc
    53281 attaatatgc atgtggtgac tgaagtccag cacattgtga ttctggcgga gcaccatctg
    53341 ctggattaca aaggcgtaga gaaacgattt agccaaattc agccattacg ttacccaaga
    53401 tggctggtag ccttaatggt tggcctttct tgcgcctgtt tctgcaaact caataaaggt
    53461 ggctgggatg gtgccgtcat caccttcttt gccagtacgg ccgcgatgta tatccgccag
    53521 ctgctggcac aacgtcatct tcatccgcag atcaactttt gcctcaccgc tttcgccgcc
    53581 accaccattt ccggattgct tttgcaactt cccactttca gcaatacacc cactatcgcg
    53641 atggccgcca gcgttctgct gctggtgccg ggatttccgt tgattaatgc cgtcgccgat
    53701 atgtttaaag gccacatcaa taccggactg gcacgctggg cgatcgccag tctgctgaca
    53761 ctggctacct gcgtcggcgt agtgatggca ctgacgattt gggggctacg cggatgggtg
    53821 tgatcgaatt tctgttagcg ttggcgcagg atatgatcct cgccgccatt cctgcggtcg
    53881 gctttgcgat ggtgttcaac gttcccgttc gggcgttacg ctggtgtgcg ctgcttggcg
    53941 cgattggtca tggttcacga atgatcttaa tgaccagcgg gctgaatatt gagtggtcaa
    54001 cttttatggc ttctatgctg gtcggcacca ttggtattca atggtcgcgc tggtatctgg
    54061 cgcatccgaa agtgtttacc gtggcggccg ttatccctat gttcccgggc atatcggctt
    54121 ataccgcaat gatttcggcg gtaaaaatca gccagttagg ttacagcgaa ccgttgatga
    54181 ttaccctgtt aaccaacttt cttacagctt catcgattgt tggtgcgtta tccatcggtc
    54241 tttccattcc tggattatgg ttgtaccgca agcgccctcg cgtataaaat tgcctcgctt
    54301 aagcacacgg atgagagaca gcctcctctc ctccgtgtgt tactataaaa gttatctccc
    54361 ttctcgttca tcgttccata tttgagaaac agtatgtctt ccagagtttt gaccccggac
    54421 gtcgttggta ttgacgccct ggtacacgat caccaaaccg ttctggcaaa agctgaaggc
    54481 ggtgtggttg ccgtatttgc taacaatgcc ccggcgtttt atgccgtcac gcctgcacgc
    54541 ctggctgaac tgctggcgct ggaagaaaag ctggcgcgtc cgggaagcga tgtcgctctg
    54601 gacgatcaac tctatcagga accgcaagcc gctcccgttg ctgtccccat ggggaaattc
    54661 gccatgtatc cggactggca acccgatgcc gactttatcc gcctggcggc gctatggggc
    54721 gtggcgctaa gagagccggt gaccaccgaa gaactggcct cattcattgc ctactggcag
    54781 gcggaaggta aagtctttca ccatgtgcag tggcaacaaa aactggcgcg cagcctgcaa
    54841 atcggtcgtg ccagcaacgg cggactgccg aaacgagatg tgaatacggt cagcgaacct
    54901 gacagccaaa ttccaccagg attcagaggg taacgatgaa aaacgttggc gacctgatgc
    54961 aacgcctgca aaaaatgatg cctgcccata tcaaacctgc attcaaaacg ggtgaagagc
    55021 tactggcctg gcagaaagaa caaggggcga tccgctccgc cgctctcgaa cgtgaaaatc
    55081 gggcgatgaa aatgcagcgc acctttaacc gctccggtat tcgtccactg catcagaact
    55141 gctcctttga gaactatcgc gttgagtgtg aagggcagat gaatgcgtta agcaaagcgc
    55201 gccagtatgt cgaagagttt gacggcaaca tcgccagctt catcttttct ggtaagccag
    55261 gaaccggcaa aaaccatctg gcggcggcaa tctgcaacga gctgctgcta cgcggtaaat
    55321 ccgtattgat catcaccgtg gccgatatta tgtcggcgat gaaagatacc ttcaggaata
    55381 gcggtaccag tgaagaacaa ctgcttaacg atctgagcaa cgttgatctg ctggtgatcg
    55441 atgagatcgg cgtgcagacc gaatcgaaat acgaaaaagt gatcatcaac cagatcgtcg
    55501 atcgccgctc ttcttccaaa cgcccaaccg ggatgctgac caacagtaat atggaagaga
    55561 tgaccaagtt gctgggcgaa cgcgtgatgg accgtatgcg cctgggtaac agtttgtggg
    55621 tgatcttcaa ctgggatagc taccgtagcc gggtaacagg taaagagtat taatccccgt
    55681 ttctggcggt atactgcgac acaattccac cttgagtaat gatgatgaaa actgttaaac
    55741 atcttctgtg ctgtgccatt gccgccagcg cattaatttc caccggggtg catgctgcgt
    55801 cctggaaaga tgcgctctcc agcgccgcca gcgaacttgg caaccaaaac agcacgacac
    55861 aggaaggcgg ttggtcgctc gcgtcattaa ctaacttgct tagcagcgga aaccaggcct
    55921 taagcgcaga taacatgaac aatgccgcag gcattctgca atactgcgcg aagcaaaagc
    55981 tggcgtcggt aaccgatgcc gaaaacatca agaatcaggt actggaaaaa ctgggcctga
    56041 acagtgaaga gcaaaaagaa gacaccaact atctggatgg cattcagggt ttgctgaaaa
    56101 ctaaagatgg tcagcaactc aatctggata atatcggaac gactccgctg gcagaaaagg
    56161 tgaaaaccaa agcctgcgat ctggtgttaa agcaggggct gaacttcatt tcctgaaccg
    56221 cgaaacgccg cgttttagct gttacccggc tgacgcggct ctctcctgcc cttttccctg
    56281 ctcctggacg gttttccccc tgttacacgg gaagcgaccg taatcaaaaa agtctgttta
    56341 taaactaatt cctaacaaca tcgcattttt ttgacactag aattgcagca atatggcgac
    56401 gccattacat tgtgcttctc aaaaagctta aacgttggct aaacggcccg gtttagtgag
    56461 gatcgcccgt tgtcagaact actctctttc gccctttttc tcgcctctgt gctgatttac
    56521 gcatggaaag cgggacgtaa cacctggtgg tttgcagcca tgttaacggt gctggggcta
    56581 tttgtcgttt taaatatcac cctgtttgcc agcgactatt ttactggcga tggtattaac
    56641 gacgcggttc tctatacctt aaccaacagc ctgaccggtg ctggtgtcag caaatacatt
    56701 cttccgggta tcggcattgt gctggggctg acggcggtgt tcggtgcgct gggctggatc
    56761 ctgcgccgtc gtcgccatca tccgcaccat tttggttaca gcctgctggc actcttactg
    56821 gcgctgggtt cagtggatgc cagcccggca tttcgtcaga taacggaact ggtgaaatcc
    56881 cagtcacgcg atggcgaccc ggactttgcg gcttattata aagagccgtc gaaaactatc
    56941 cctgacccga aactcaacct ggtttatatc tacggcgaaa gtctcgagcg gacctatttt
    57001 gataacgaag ctttcccgga tctcacgcct gaactgggcg cgttgaaaaa tgaaggcctg
    57061 gatttcagcc acacgcagca gctgccagga acggattaca cgattgcggg catggtggct
    57121 tctcagtgcg gcataccgct gtttgccccc tttgaaggca acgcctccgc ctctgtctcc
    57181 agcttcttcc cgcagaacat ctgtctgggc gatatcctga aaaactcggg ttatcagaac
    57241 tatttcgtgc agggcgcgaa tctgcgtttt gccggtaaag atgtgttcct gaagtcgcat
    57301 ggcttcgacc acttatacgg ctcagaagag ctgaaaagcg tggtggccga cccgcactat
    57361 cgcaacgact ggggattcta cgacgatacc gttctcgatg aagcgtggaa aaagtttgaa
    57421 gagctttccc gctcaggtca gcgattctca ctgtttaccc tgacagtcga tacccatcac
    57481 ccggatggtt ttatctcgcg tacctgtaac cgcaaaaaat atgattttga cggtaagccg
    57541 aaccagtcat tcagcgcggt aagttgcagc caggagaata tcgcggcgtt tatcaacaaa
    57601 atcaaagcgt caccgtggtt taaagatacc gtcatcgtcg tctcttctga ccatttagcg
    57661 atgaacaaca cggcgtggaa ataccttaat aagcaggatc gcaataacct gttttttgtc
    57721 attcgtggcg acaagccgca gcaagagacg ctggcagtga agcgtaacac gatggataac
    57781 ggcgcgacgg tgctggacat tctcggtggc gataactatc tcggacttgg tcgtagcagt
    57841 ttatccgggc agtcaatgtc ggaaatcttc ctcaatatca aagagaaaac attggcgtgg
    57901 aagccggata tcatccgcct gtggaaattc cctaaagaga tgaaagagtt caccatcgac
    57961 cagcagaaaa acatgattgc cttctcgggt agccatttcc gtttgccact gctgttgcgg
    58021 gtttcagaca aacgcgtgga accgctgccg gaaagcgaat actcagcacc gctgcgtttc
    58081 cagctggccg atttcgctcc acgcgacaat ttcgtctggg ttgaccgttg ctataagatg
    58141 gcacaactct gggctccgga actggcactc tccaccgact ggtgtgtctc gcaagggcag
    58201 cttggcggtc agcaaattgt tcagcatgtt gacaaaacaa catggcaggg caaaacggca
    58261 tttaaagata cggtcatcga catggcgcgt tataaaggca atgtcgatac gctgaaaatt
    58321 gttgataacg atattcgcta caaagccgac agtttcatct tcaacgtcgc cggtgcgcca
    58381 gaagaggtga aacagtttag tgggatttcc cgtccagagt cgtggggccg ctggtccaac
    58441 gcgcagctgg gcgatgaagt aaaaatcgag tacaagcatc cgctgccgaa gaaatttgac
    58501 ctggtgatta ccgccaaagc atacggcaat aacgccagcc gtcctattcc ggtacgcgta
    58561 ggcaatgaag aacaaactct tgtgctgggc aatgaagtga ccaccaccac actgcatttc
    58621 gataacccaa ccgatgccga cacactggta attgtgccgc cggaacctgt ctcaaccaac
    58681 gaagggaata tcctcggaca ctcgccgcgt aagctcggga tcggcatggt ggaaattaaa
    58741 gttgtggaac gtgaagggta atttctgact gatgtgtagg tcgcataagg tgcgacctac
    58801 acatcttctc cggcctacaa aacatcattg agaaacagaa aaaaaacagc gcccaacact
    58861 tccccggacg ctgcatggca actttaataa tctcgcctta tcagaaagta attacaccct
    58921 taatcaactc acgattgtta atcacatcgc gctcgtaggt ttctgccagc gtggcgaacg
    58981 gatagcgatg ggttaacatc atgtcggcag tgatttttcc ttccgccatc agtcgaccga
    59041 ctttagcaaa atcttccggc gtggcgttgc ggctgcccat catcgtcgtt tcttttttat
    59101 ggaattccgg atcggagaac tgcaactcac ctttaaacag gccgacaaat accaccgtgc
    59161 cgccgtgacg aatcaaattc acggtgttat tcatcgcatg ttgattacct gtcgcgtcga
    59221 tcactttctg cgccagcgaa ccaccaaact gcgcccgtag ctgcgcgtca aaatcttcgg
    59281 ctgacgggtc cagtaaaggt aattccagac gcgttgccac atggtcacgg cgcgccggac
    59341 tggtatccgc caccaccacc tgtgcgccat cggctttagc gattgccgcc gcgcccagac
    59401 cgattggccc cgccccgacc accagcacct gctcgccggg agcaatggct gcgcgacgca
    59461 ccgcatgagc gctaatagcg aaaggttcaa tcaatgctgc cgcctgcggg tcaataccgt
    59521 ctgcgggcaa aatgttcgcc accggcacgc tcaaatactc actaaaaccg ccatcctgat
    59581 gcacgccaat gactgaaatt ttttcacagc aattggtacg cccgctttta cacgccgggc
    59641 attgctgaca ggcaacataa gggatcacag caacttgctg accattttta agatcagcaa
    59701 tatttttacc cagcccaaca atctccccac atatttcatg gcctaaaaca cgtggataac
    59761 taaaaaatgg ttgatttcca ccccaggcat gaatatcggt accacaaatc ccgacagact
    59821 taatttttat taatgcttca ttgtcacccg gaataggtat ctcgcgttgt ttccagacta
    59881 attctttcgg ctgctggcaa attaaaacat tcatcgtaga catgattcgg ctctccattt
    59941 tttgttgcct tagatatcaa taaaaatgaa aaatggcagc ggaacggaaa atctgttttg
    60001 tgaaaacaca cgcataaaaa tgttttaaat cgggttttaa tggactcaca aggaggaaaa
    60061 tatgagtcgt tcacaaaatt tacgccacaa tgtgattaac caggtcattg atgatatggt
    60121 gcggggtcat atcccttccc cacttccatc gcaaagtgcg ctggcggaaa tgtacaacat
    60181 cagccgcact acagtgcgtc atattctcag ccacttacgc gaatgcggcg tcttaacgca
    60241 ggttggaaac gactatgtga ttgcgcgtaa acctgaccat gatgacggtt tcgcctgtac
    60301 taccgcttca atgagtgaac aaaacaaagt gtttgagcag gcttttttca cgatgataaa
    60361 ccagcgccag ttacgccctg gggaaacttt ttctgaactg caactggctc gggccgcggg
    60421 tgtcagcccg gttgtagtaa gagaatatct tttaaaattc ggccgttata atcttattca
    60481 aagcgaaaag cgcggccagt ggagcatgaa gcaattcgat caatcctacg ccgagcagct
    60541 gtttgaacta cgcgaaatgc tcgaaacaca ttcacttcag cactttctca acctgcctga
    60601 tcatgatccc cgctggctgc aggcgaaaac catgctcgaa cgtcatcggc tactgcgtga
    60661 caacatcggc aatagctttc gcatgttctc gcaacttgac agagattttc actccttact
    60721 gctttcagct gccgacaata tcttttttga tcaatctctt gagatcatct cagtcatctt
    60781 tcattttcac tatcaatggg acgaaagcga tcttaaacag cgcaatatca ttgccgtcga
    60841 tgagcatatg accattctca gcgctctgat ttgccgcagt gaccttgatg ccacccttgc
    60901 gctccgtaac catttgaatt cagctaaaca atcaatgatt cgatccatta atgagaacac
    60961 gcgttatgct cattaagtac ggattaaaaa cagcaaacta ttagcggtgc acggttttat
    61021 caaaagataa ataccgggaa attcccgctt acctatgctc acaatcagtc gactaaaaat
    61081 gtttttgtga gcggtagtaa agtcctaaaa ctttaacctg ccgttaatgt caaccttgcg
    61141 taatgcacaa ttacgtaaac aattaaaatt ataaatacag gagtccggcg tggaaaaaga
    61201 aaatatcacc ctcgatccgc gttcttcatt tactccatct tcgtcggcag atattcccgt
    61261 gccaccagat ggattagttc aacgcagtac ccgaattaaa cgcattcaaa ccaccgccat
    61321 gttgttatta ttttttgcgg cggtaatcaa ttatctcgac cgcagttcgc tgtcggtagc
    61381 aaatttaacg attcgtgaag aattgggatt aagtgccacc gaaatcggcg ctttgctctc
    61441 cgtgttttca ctcgcttacg ggattgcgca acttccttgc ggcccactat tggatcgtaa
    61501 aggcccacgc ctgatgctgg gactggggat gttcttctgg tcactgttcc aggccatgtc
    61561 tggcatggtg cacagcttta cgcagttcgt gttggtgcgt atcggtatgg ggattggtga
    61621 agcgccgatg aacccatgtg gcgtaaaagt cattaacgac tggttcaaca tcaaagagcg
    61681 cggacgcccg atgggcttct tcaacgcagc ttctaccatt ggcgttgccg taagcccacc
    61741 gattctggcg gcgatgatgc tggtgatggg ctggcgtggg atgtttatta ccattggtgt
    61801 gctggggatt tttctcgcca ttggctggta tatgctctat cgcaaccgcg agcacgtaga
    61861 actgactgcc gttgaacaag cttatctcaa tgcaggtagc gtcaatgccc gccgagatcc
    61921 gctcagtttt gccgaatggc gcagcctgtt ccgtaaccgc acaatgtggg gaatgatgct
    61981 cggattcagt ggcatcaact acactgcgtg gctgtatctg gcctggcttc ctggttacct
    62041 gcaaacagcc tataacctgg atttaaaaag cacagggttg atggcggcta tccctttcct
    62101 gtttggggct gccgggatgc tggtcaacgg ttacgttact gactggctgg tcaaaggggg
    62161 aatggctccg attaaaagcc gtaagatctg cattattgcc gggatgttct gttctgccgc
    62221 ctttacgctg gtcgtaccgc aagcgacaac atccatgacg gcggttctgc tgattggcat
    62281 ggcactgttc tgtattcact ttgccggaac atcctgctgg ggcttgatcc acgtcgcagt
    62341 tgcttctcgc atgacggcgt cggtgggcag tatccagaac tttgccagct tcatctgcgc
    62401 ctcttttgcg ccgatcatta ctggttttat tgttgatacc acccactcat tccgtctggc
    62461 actaatcatc tgcggttgcg tcaccgcagc gggagcactg gcgtacatct tcctggttcg
    62521 tcagccgatc aacgacccgc gtaaagatta aactccctat gcccgataac attttgctta
    62581 tcgggcattt ttatggcgat taaaacgttt cccagttctc cccgctatct gccactgcca
    62641 ttttacgcgg cgtagctggc gtcacgtttt ttaccacagc cgatgtttca cgctgctgtt
    62701 gctgctgttg ctgaatccgg aacactgcca cagcttcggt caggcgactg gcctgctctt
    62761 ccagcgcggc ggcggcagcg gcagattctt ccaccagcgc agcgttctgt tgagttaccc
    62821 ggtccatctc agcaaccgct aagccaacct gatcgatacc acggctctgc tcatcagaag
    62881 cagaagcaat ttcgcccata atgtccgtca cgcgggtcac ggcactgaca atctccgcca
    62941 ttgtttcccc tgcgctttcg accagcgtag agccaacatc tactttcccc accgagtctt
    63001 caatcaggct tttaatttca cgagccgcct gagcgctgcg ctgggccaga ttacgcactt
    63061 cacccgcgac caccgcaaaa ccgcgccctt gctcacccgc gcgcgctgct tcaaccgccg
    63121 cgttcaaagc cagaatattg gtctggaagg caatgccgtc aattacgctg ataatatcgg
    63181 cgattttctg cgaactggtg gagatatcgc gcatagtctg caccacgtta tctaccactt
    63241 tgccgccgcg ttgcgccgtt tcagaagcac ttaacgccag gtggctggcc tggcgcgcat
    63301 tttcggcgtt ctgtttcacc gttgcggtca gttgctccat gctggctgcc gtctcttcca
    63361 gcgaagcggc ctgttgctcg gtgcgcgaag agagatcgtt attgccggta gcgatttcgc
    63421 tggcaccgct atagatggca ttggccccgt tgcgcacatc accgacggta cgcatcagct
    63481 ctccctgcat atggcgcaaa ctctctgcca gttgccccat ctcattagag ccatccacct
    63541 caatcggttt caccagatcg ccgcctgcaa tatgacgaat gctgtcaatc aggcgattca
    63601 ttggcgctac caacgaggct ttaataccga accagacggc gaagatgact gccagtacga
    63661 cgatcatcac gcccaccaga atccacatcg cctggctgta ggaggcatta ttatcgctga
    63721 cggcgatatc atagagccga tcgttttgct ccatgtaagc cacatactgc ttctcgaaac
    63781 cgtcctgata tccctgggtc ggctgatcaa agaactcgtt gattttgcct gcacctaaca
    63841 gttggatcag ctccgccagc gcattgtgat aaatatcgta attacgtttg atctctgccg
    63901 ctgcggcggt gctctgacgc gggtcacgcg gcaacgcttc gtaatccgcc cagttttttt
    63961 ccgcctgttt cagcgaaata ctggcactct ccatcagctc agcaacggtt gaaccgctac
    64021 caatattatt ctgatccatc atgtagcgga tacccgcgcg gttgagggtg ttacgcgtct
    64081 gcaacaacgc gacccagctg ccattcagcg tggattgctg ctggcgaatg gtttgtaaaa
    64141 cagtgaaatt ttctttgtca ttctttaagg cattaaagaa cagaccgcct gatgtcagtt
    64201 gtaaaaggcc aaaaacggcc aaaaccagca gtaagctggt cacaattttg atacgtttta
    64261 acatggtttc tctttcctgt ggaccgatgc aagattttcg gccaggaaag gaaaaacttt
    64321 atgaatatcc cgcggagatt acgccgagta attttattca cactctgaat ttaaaaagcc
    64381 attatttaca taaattactc acaatataaa tatgtgatat gaatcacata tttatcgtca
    64441 cttaaacgac gcctttgccg ctcaaccgca aaactgaccg cttacatccc taaaataacc
    64501 actcagttat ttaccttact ttacgcgcgc gtaactctgg caacatcact acaggatagc
    64561 ggtcaattta cctcctcaaa cgcaacgcaa acctagaacg gcttcggcca actattaatc
    64621 aatacatgcc aggttttact atggatacta aaaagatatt caagcacata ccctgggtga
    64681 ttctcggaat catcggtgca ttctgcctcg cggtagttgc attacgtcgg ggggagcacg
    64741 tcagcgccct gtggatcgtg gtcgcctctg tgtcggtgta tctggtggcg tatcgctact
    64801 acagtctgta catcgcccag aaggtgatga aactcgaccc cacgcgcgcg acgcctgcgg
    64861 ttattaacaa cgacggtctg aactacgttc cgaccaaccg ttacgtgttg tttggtcacc
    64921 acttcgccgc tatcgccggt gcaggtccgc tggtgggtcc ggttctcgcc gcgcagatgg
    64981 gctacctgcc tggcacgctg tggctgctgg cgggggtcgt gctggccggt gcggttcagg
    65041 actttatggt gctgtttatc tcctctcgcc gtaatggcgc atctcttggt gagatgatca
    65101 aagaagagat gggaccagta ccggggacta tcgcgctgtt tggctgtttc ttaatcatga
    65161 tcatcatcct cgccgtcctg gcgctgattg tggttaaagc cctggccgaa agtccgtggg
    65221 gtgtcttcac cgtttgctca accgtaccga ttgcgctgtt tatgggtatc tacatgcgct
    65281 ttatccgtcc ggggcgtgtg ggtgaagtct ctgtcattgg tatcgtgctg ctggttgcct
    65341 ctatctactt cggtggcgtg attgctcacg atccgtactg gggtccggca ctgaccttta
    65401 aagacaccac cattaccttc gcgctgattg gctatgcgtt tgtttccgca ctgctgccgg
    65461 tgtggctgat cctcgcaccg cgcgactatc tggcaacctt cctgaaaatc ggcgttatcg
    65521 tcggcctggc gctgggtatc gtggtgctga acccggaact gaaaatgcct gcgatgaccc
    65581 agtacattga cggtactggc ccgctgtgga aaggcgctct gttcccgttc ctgttcatca
    65641 ccatcgcctg tggtgcggta tctggcttcc acgcgctgat ctcttccggt acgacgccga
    65701 aactgctggc taacgaaacc gacgcgcgtt tcattggcta cggcgcaatg ctgatggagt
    65761 ccttcgtggc gattatggcg ctggttgctg cgtccatcat cgaaccgggt ctttacttcg
    65821 cgatgaatac cccgcctgcg ggccttggca tcaccatgcc taacctgcat gaaatgggtg
    65881 gcgagaacgc gccgatcatc atggcgcagc tgaaagacgt taccgcacac gcggcggcga
    65941 ccgtcagctc ctggggcttc gtgatttcgc cagagcagat cctgcaaacc gcgaaagaca
    66001 ttggtgagcc ttctgtcctg aaccgtgcag gtggtgcgcc gacgctggcg gtaggtatcg
    66061 ctcatgtgtt ccacaaagtg ctgccgatgg ctgacatggg cttctggtat cacttcggta
    66121 ttctgttcga agccctgttc atcctgaccg cgctggatgc gggtacccgt tctggccgct
    66181 ttatgctgca agacctgctg ggtaacttca tcccgttcct gaaaaaaacc gactctctgg
    66241 ttgccggtat catcggtact gcgggctgtg tgggtctgtg gggctacctg ctgtatcagg
    66301 gcgtggtcga tccgctgggc ggcgttaaga gcctgtggcc gctgttcggt atctccaacc
    66361 agatgctggc agccgtagcg ctggtactgg gcaccgttgt gctgattaag atgaagcgca
    66421 cccaatacat ctgggtaact gttgttccgg ctgtatggct gcttatctgc accacctggg
    66481 cgctgggtct gaaactgttc agcaccaacc cgcagatgga aggcttcttc tacatggcaa
    66541 gccagtacaa agagaagatt gctaacggta ctgacctgac ggcgcagcag attgccaaca
    66601 tgaaccacat cgttgtgaac aactacacca acgcgggcct gagtattctg ttcctgattg
    66661 tggtgtacag catcatcttc tacggtttca aaacctggct tgcggtgcgt aacagcgaca
    66721 aacgtactga caaagaaaca ccgtacgttc caatcccgga aggcggcgtg aagatctctt
    66781 cgcaccacta accgtgttta gccccgcttc ggcggggctt tgttcttatc agagtgaact
    66841 atgtttggta acttaggaca ggcaaaaaaa tatctcggcc aggcggcaaa gatgttgatt
    66901 ggcattccag actacgacaa ctacgtcgag catatgaaga ccaaccatcc cgacaagccg
    66961 tacatgagct atgaagaatt cttccgcgaa cgccagaacg cgcgctacgg cggcgatggt
    67021 aaaggcggta tgcgctgttg ttaatggaga gagcatgaac ccgattgcag ttaccctact
    67081 caccggtttt ttaggcgcgg gaaaaaccac cctgctgcgc catattctta acgaacaaca
    67141 cggctacaag attgccgtga ttgaaaacga attcggcgaa gtctccgttg atgatcaact
    67201 aattggcgac cgcgccacgc agatcaaaac gctgaccaac ggctgcatct gctgttcgcg
    67261 ctccaacgag ctggaagacg cactactcga cctgctggat aatctcgaca agggcaatat
    67321 tcagtttgac cgtctggtca ttgaatgcac cggcatggcc gatcccggcc cgattattca
    67381 gacctttttc tcccatgaga ttttatgcca gcgttacctg ctggacggtg tgattgcgct
    67441 ggtggatgcg gtacatgccg acgagcagat gaaccagttc accatcgccc agtcccaggt
    67501 tggctacgcc gaccgtattc tgctgaccaa aaccgacgtc gcaggcgaag cagaaaaact
    67561 gcgtgaacgc ctggcgcgca tcaacgcccg tgcaccggtc tacaccgtca cccacggcga
    67621 catcgacctg ggcctgctgt tcaacaccaa cggttttatg ctggaagaga acgtcgtcag
    67681 caccaaaccg cgtttccact ttatcgcgga taaacaaaac gatatttcgt cgattgtggt
    67741 ggaactggat tacccggtag atatcagcga agtttcccgg gtgatggaaa acctgcttct
    67801 ggaatcggca gataaactgc tgcgttacaa agggatgctg tggattgacg gcgaacctaa
    67861 ccgcctgctg ttccagggcg tccagcgcct ctacagcgcc gactgggacc gcccgtgggg
    67921 cgatgaaaaa ccgcatagca caatggtgtt tatcgggatt cagttgccag aggaagagat
    67981 tcgggcagcg tttgcggggt tgaggaagta attttggatg atggccgcca tgtggcggcc
    68041 tgaattattt tttgttctga tcgcgcagca tcgcttcacg taaaattgcg ttcaggcgag
    68101 tttgatagcc tttacctggt cgcttcaacc attccatcac atcagcatca atacgcaccg
    68161 aagcctgagt tttcaatggc cgataaaact taccgcgttc ggcgttagac cattgctcat
    68221 cgctggaagg tgggatatca ctgtaatcaa tatcttcgtc ggatttattc gtcagcgcct
    68281 tcagttcggc ctcatgctgc acatcgagtg tagaggaggt ccctcgttta tgtttaacca
    68341 tgctcatagc gattcctctc tttacgatct gcttttcgtg cactgatgat tcgaataatt
    68401 tcatttccgc tttcgaaacg gatggtatgc gcaaccagaa taaccacgat gccgtaaacc
    68461 aggccgattg tctgccagcg atactcaccg ttttctatgc gttcttgctg tgacaaatgt
    68521 tgtggatcat caaacaataa caccgcatct tcaaagcgga tgccatgttt cacccgatta
    68581 cttttggcct tgttttcatc ccattcaaac tccattggca taattgccat ccctaattgt
    68641 atatacaaaa atgtatctac aattattctg caattatagc gttgatgttg gaaatagcat
    68701 cacgtttcga ataatcaacc atgaaattga caatgagtaa gttggacttg attcatccaa
    68761 tagaatttct cgcctgacat ggcacactaa acacctcgct gtcgggtaat gactccaact
    68821 tac
//
LOCUS       DACAOP010000013        67597 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.013, whole genome shotgun sequence.
ACCESSION   DACAOP010000013 DACAOP010000000
VERSION     DACAOP010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 67597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67597
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.013"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            9..926
                     /locus_tag="IT892_000962"
     CDS             9..926
                     /locus_tag="IT892_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001351801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M28 family peptidase"
                     /protein_id="HAP3134201.1"
                     /translation="MIFYQPWVNALPPTPRHASPEQLEKTVRYLTQTVHPRSADNIDN
                     LKRSAEYIKEVFVSSGARVTAQDVPITGGPYKNIVADYGPADGPLIIIGAHYDSASSY
                     ENDQLTYTPGADDNASGVAGLLELARLLQQQVPKTGVQLVAYASEEPPFFRSDEMGSA
                     VHAASLERPVRLMIALEMIGYYDSAPDSQNYPYPAMSWLYPDRGDFIAVVGRMQDINA
                     VRQLKAALLSSQDLSVYSMNAPGFIPGIDFSDHLNYWQHDIPAVMITDTAFYRNKQYH
                     LPGDTADRLNYQKMAQVVDGVITLLYNSK"
     gene            1029..1532
                     /locus_tag="IT892_000963"
     CDS             1029..1532
                     /locus_tag="IT892_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HAP3134202.1"
                     /translation="MGMIGYFAEIDSEKINQLLESTEKPLMDNIHDTLSGLRRLDIDK
                     RWDFLHFGLTGTSAFDPAKNDPLSRAVLGEHSLEDGIDGFLGLTWNQELAATIDRLES
                     LDRSELRKQFSIKRLNEMEIYPGVTFSEELEGQLFASIMLDMEKLISAYRRMLRQGNH
                     ALTVIVG"
     gene            complement(1599..3056)
                     /gene="nuoN"
                     /locus_tag="IT892_000964"
     CDS             complement(1599..3056)
                     /gene="nuoN"
                     /locus_tag="IT892_000964"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HAP3134203.1"
                     /translation="MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIG
                     LNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNK
                     DEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
                     ILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKL
                     SLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAII
                     AFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYL
                     FSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGF
                     IGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQY
                     SAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM"
     gene            complement(3063..4592)
                     /gene="nuoM"
                     /locus_tag="IT892_000965"
     CDS             complement(3063..4592)
                     /gene="nuoM"
                     /locus_tag="IT892_000965"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HAP3134204.1"
                     /translation="MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMGLTLALSL
                     QLWLQGGYSLTQSAGIPQWQSEFDMPWIPRFGISIHLAIDGLSLLMVVLTGLLGVLAV
                     LCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
                     ASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYNATGVWTFNYEELLNTPMSNG
                     VEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSL
                     PLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSVSHMGFVLIAIYTGS
                     QLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFA
                     VATLGMPGTGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKS
                     QIASQELPGMSLRELFMILLLVVLLVLLGFYPQPILDTSHSAIGNIQQWFVNSVTTTR
                     P"
     gene            complement(4823..6664)
                     /gene="nuoL"
                     /locus_tag="IT892_000966"
     CDS             complement(4823..6664)
                     /gene="nuoL"
                     /locus_tag="IT892_000966"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HAP3134205.1"
                     /translation="MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALV
                     TAFIGVDFFANGEQAYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMY
                     ASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTD
                     PKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWA
                     TLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMT
                     PEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFH
                     LMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLV
                     TAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKG
                     VTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLA
                     AWLWLGKRTLVTSIANSAPGRLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLN
                     SMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR"
     gene            complement(6661..6963)
                     /gene="nuoK"
                     /locus_tag="IT892_000967"
     CDS             complement(6661..6963)
                     /gene="nuoK"
                     /locus_tag="IT892_000967"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HAP3134206.1"
                     /translation="MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASAL
                     AFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG"
     gene            complement(6960..7514)
                     /gene="nuoJ"
                     /locus_tag="IT892_000968"
     CDS             complement(6960..7514)
                     /gene="nuoJ"
                     /locus_tag="IT892_000968"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HAP3134207.1"
                     /translation="MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFF
                     SLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAI
                     MLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
                     EERAGEVLSNRKDDSAKRKTEEHA"
     gene            complement(7526..8068)
                     /gene="nuoI"
                     /locus_tag="IT892_000969"
     CDS             complement(7526..8068)
                     /gene="nuoI"
                     /locus_tag="IT892_000969"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015959823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HAP3134208.1"
                     /translation="MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRY
                     RGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFC
                     GLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
                     KDKGEAENEAKPIDVKSLLP"
     gene            complement(8083..9060)
                     /gene="nuoH"
                     /locus_tag="IT892_000970"
     CDS             complement(8083..9060)
                     /gene="nuoH"
                     /locus_tag="IT892_000970"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015875065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HAP3134209.1"
                     /translation="MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQ
                     NRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVP
                     VSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
                     GLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAE
                     QELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTA
                     FFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ"
     gene            complement(9057..11783)
                     /gene="nuoG"
                     /locus_tag="IT892_000971"
     CDS             complement(9057..11783)
                     /gene="nuoG"
                     /locus_tag="IT892_000971"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HAP3134210.1"
                     /translation="MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGA
                     CRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISIDDEEAKQFRESVVEWLMTNHPHD
                     CPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
                     YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRK
                     WDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLK
                     DRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGE
                     ENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALA
                     VRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAP
                     VEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIISGTNAGSAE
                     VIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGRADAVVV
                     LENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNE
                     GRAQRFFQVYDPAYYDSKTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPE
                     LAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDIDTMFTFSMEG
                     NNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENGLDYFTS
                     VPARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQSRMPQPYIKLNPADAAKLGVNAGT
                     RVSFSYDGNTVTLPVEIAEGLTAGQVGLPMGMSGIAPVLAGAHLEDLKEAQQ"
     gene            complement(11836..13173)
                     /gene="nuoF"
                     /locus_tag="IT892_000972"
     CDS             complement(11836..13173)
                     /gene="nuoF"
                     /locus_tag="IT892_000972"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HAP3134211.1"
                     /translation="MKNIIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTG
                     LSPDEIVNQVKDAGLKGRGGAGFSTGLKWSLMPKDESMNIRYLLCNADEMEPGTYKDR
                     LLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVNLRRAIAEATEAGLLGKNI
                     MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGVWGKPTCVNN
                     VETLCNVPAILANGVEWYQNISKSKDAGTKLMGFSGRVKNPGLWELPFGTTAREILED
                     YAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSRLGTALAMAVDHEIN
                     MVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLG
                     PGKTFCAHAPGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW"
     gene            complement(13170..13670)
                     /gene="nuoE"
                     /locus_tag="IT892_000973"
     CDS             complement(13170..13670)
                     /gene="nuoE"
                     /locus_tag="IT892_000973"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HAP3134212.1"
                     /translation="MHENQQPQTEAFELSAAEREAIEHEMHHYEDPRAASIEALKIVQ
                     KQRGWVPDGAIHAIADVLGIPASDVEGVATFYSQIFRQPVGRHVIRYCDSVVCHINGY
                     QGIQAALEKKLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHAHLTPEAIPE
                     LLERYK"
     gene            complement(13673..15475)
                     /gene="nuoC"
                     /locus_tag="IT892_000974"
     CDS             complement(13673..15475)
                     /gene="nuoC"
                     /locus_tag="IT892_000974"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C/D"
                     /protein_id="HAP3134213.1"
                     /translation="MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATR
                     TGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHL
                     ISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMM
                     PQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFL
                     NLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIE
                     YLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMT
                     PVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLA
                     SYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENF
                     DFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERT
                     LQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSY
                     AHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR"
     gene            complement(15569..16231)
                     /locus_tag="IT892_000975"
     CDS             complement(15569..16231)
                     /locus_tag="IT892_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017490251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit B"
                     /protein_id="HAP3134214.1"
                     /translation="MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLND
                     MVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTC
                     FTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
                     RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPD
                     EI"
     gene            complement(16247..16690)
                     /gene="nuoA"
                     /locus_tag="IT892_000976"
     CDS             complement(16247..16690)
                     /gene="nuoA"
                     /locus_tag="IT892_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoA"
                     /protein_id="HAP3134215.1"
                     /translation="MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARAR
                     SKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVE
                     AAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR"
     gene            complement(17321..18259)
                     /gene="lrhA"
                     /locus_tag="IT892_000977"
     CDS             complement(17321..18259)
                     /gene="lrhA"
                     /locus_tag="IT892_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LrhA"
                     /protein_id="HAP3134216.1"
                     /translation="MISANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQ
                     QMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLT
                     IGASDESADTILPFLLNRVSSVYPKLALDVRVKRNAYMAEMLESQEVDLMVTTHRPST
                     FKALNLRTSPTHWYCAAEYVLQKGEPIPLVLLDDPSPFRDMVLATLNKADIPWRLAYV
                     ASTLPAVRAAVKAGLGVTARPVEMMSPDLRVLSGVDGLPPLPDTEYLLCYDPSSNNEL
                     AQVIYQAMESYHNPWQYSPMSAPEGDDSLLIERDIE"
     gene            19179..20396
                     /locus_tag="IT892_000978"
     CDS             19179..20396
                     /locus_tag="IT892_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP3134217.1"
                     /translation="MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPA
                     PFGFDAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGN
                     GVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
                     IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDA
                     EHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRL
                     CANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSCVKPRGALYM
                     FPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSL
                     SKFARFLSSYHQL"
     gene            20480..21079
                     /gene="yfbR"
                     /locus_tag="IT892_000979"
     CDS             20480..21079
                     /gene="yfbR"
                     /locus_tag="IT892_000979"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HAP3134218.1"
                     /translation="MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHAL
                     AAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQ
                     KLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAK
                     TRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL"
     gene            complement(21138..22970)
                     /locus_tag="IT892_000980"
     CDS             complement(21138..22970)
                     /locus_tag="IT892_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HAP3134219.1"
                     /translation="MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLT
                     VPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMGTWLVKVAGNSEIKMLVLLMLTV
                     AGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
                     VNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFR
                     DLIREYRLTGRARRLAIRPGSPMIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVN
                     GVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQALDVGMAEISLIPE
                     SELIGKSVREIGFRTRYGLNVVGLKRNGEAMEGSLADEPLLLGDIILVVGNWKLIGML
                     AKQGRDFVALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLM
                     GKFRCIDAESAYKSIHWPSIILIVGMMPFAVALQKTGGVALAVKGLMDIGGGYGPHMM
                     LGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASAAFMTPV
                     SSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF"
     gene            complement(23057..23707)
                     /gene="hxpA"
                     /locus_tag="IT892_000981"
     CDS             complement(23057..23707)
                     /gene="hxpA"
                     /locus_tag="IT892_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HpxA"
                     /protein_id="HAP3134220.1"
                     /translation="MRCKGFLFDLDGTLVDSLPAVERAWSNWARRHGLAPEEVLAFIH
                     GKQAITSLRHFMAGKSEADIAAEFTRLEQIEATETEGITALPGAIALLNHLNKAGIPW
                     AIVTSGSMPVARARHKVAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
                     VEDAPAGVLSGLAAGCHVIAVNAPADTPRLNEVDLVLHSLEQITVTKQPNGDVIIQ"
     gene            complement(23718..24212)
                     /locus_tag="IT892_000982"
     CDS             complement(23718..24212)
                     /locus_tag="IT892_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007371080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HAP3134221.1"
                     /translation="MEMTNAQRLILSNQYKMMTMLDPANAERYRRLKTIIERGYGLQM
                     RELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEAR
                     YLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
                     IINA"
     gene            complement(24295..24750)
                     /locus_tag="IT892_000983"
     CDS             complement(24295..24750)
                     /locus_tag="IT892_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF412 domain-containing protein"
                     /protein_id="HAP3134222.1"
                     /translation="MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMT
                     RYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAI
                     LNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL"
     gene            25088..26290
                     /gene="ackA"
                     /locus_tag="IT892_000984"
     CDS             25088..26290
                     /gene="ackA"
                     /locus_tag="IT892_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAP3134223.1"
                     /translation="MSSKLVLVLNCGSSSLKFAIIDAVNGEEYLSGLAECFHLPEARI
                     KWKMDGNKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSS
                     VVIDESVIQGIKDAASFAPLHNPAHLIGIEEALKSFPQLKDKNVAVFDTAFHQTMPEE
                     SYLYALPYNLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVS
                     AIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKESGL
                     LGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGAYTALMDGRLDAVVFTGGI
                     GENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIA
                     QDASRLTA"
     gene            26365..28509
                     /gene="pta"
                     /locus_tag="IT892_000985"
     CDS             26365..28509
                     /gene="pta"
                     /locus_tag="IT892_000985"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAP3134224.1"
                     /translation="MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPR
                     TGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLSSNQKDVLMEEIVANYHANTKDA
                     EVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFG
                     GAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSSKAKVNNVDPAKLQESSPLPVL
                     GAVPWSFDLIATRAIDMARHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSL
                     LVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNT
                     NTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIDSLTATSERSRRLSPPAF
                     RYQLTELARKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGV
                     ELGAGIEIVDPEVVRESYVGRLVELRKNKGMTETVAREQLEDNVVLGTLMLEQDEVDG
                     LVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQL
                     AEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGP
                     LQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQG
                     MRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ"
     gene            28699..30219
                     /gene="yfcC"
                     /locus_tag="IT892_000986"
     CDS             28699..30219
                     /gene="yfcC"
                     /locus_tag="IT892_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP3134225.1"
                     /translation="MSAITESKPTRRWAMPDTLVIIFFVAILTSLATWVVPVGMFDSQ
                     EVQYQVDGQTKTRKVVDPHSFRILTNEAGEPEYHRVQLFTTGDERPGLMNFPFEGLTS
                     GSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRHTRGNEILFIPALFILFSL
                     GGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQ
                     GIAGVPVLSGSGLRIVVWVIATLIGLIFTMVYASRVKKNPLLSRVHESDRFFREKQAD
                     VEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPEIASQFFTMGLVIGIIGVVFRL
                     NGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGDASVLNTILNSIANAI
                     SGLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFG
                     DGFSHIIYPTSASLMATLGVCRVDFRNWLKVGATLLGLLFIMSSVVVIGAQLMGYH"
     gene            complement(30252..30794)
                     /gene="yfcD"
                     /locus_tag="IT892_000987"
     CDS             complement(30252..30794)
                     /gene="yfcD"
                     /locus_tag="IT892_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="HAP3134226.1"
                     /translation="MEQRRLASTEWVDIVNEENEVIAQASREQMRAQCLRHRATYIVV
                     HDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFAE
                     HGQFYFEDKNCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLKA
                     LALWMKRNAKNEAVETETAE"
     gene            complement(30852..31403)
                     /gene="yfcE"
                     /locus_tag="IT892_000988"
     CDS             complement(30852..31403)
                     /gene="yfcE"
                     /locus_tag="IT892_000988"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311211.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HAP3134227.1"
                     /translation="MKLMFASDIHGSLPATERVLELFAQSGAQWLVILGDVLNHGPRN
                     ALPEGYAPAKVAERLNEVAHKVIAVRGNCDSEVDQMLLHFPITAPWQQVLLEKQRLFL
                     THGHLFGPENLPALNQNDVLVYGHTHLPVAEQRGEIFHFNPGSVSIPKGGNPASYGML
                     DNDVLSVIALNDQSIIAQVAINP"
     gene            complement(31459..32103)
                     /gene="yfcF"
                     /locus_tag="IT892_000989"
     CDS             complement(31459..32103)
                     /gene="yfcF"
                     /locus_tag="IT892_000989"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
                     /protein_id="HAP3134228.1"
                     /translation="MSKPAITLWSDAHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGE
                     HLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRFAPPTWERIYPLDLENRARA
                     RQIQAWLRSDLMPIREERPTDVVFAGAKKAPLTAEGKASAEKLFAMAEHLLALGRPNL
                     FGEWCIADTDLALMINRLVLHGDEVPERLVDYATFQWQRASVQRFIALSAKQSG"
     gene            32243..32890
                     /gene="yfcG"
                     /locus_tag="IT892_000990"
     CDS             32243..32890
                     /gene="yfcG"
                     /locus_tag="IT892_000990"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="HAP3134229.1"
                     /translation="MIDLYFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFL
                     RISPNNKIPAIVDHSPADGGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLF
                     WQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
                     IADIACWPWVNAWSRQRIDLAMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS"
     gene            32947..33309
                     /gene="folX"
                     /locus_tag="IT892_000991"
     CDS             32947..33309
                     /gene="folX"
                     /locus_tag="IT892_000991"
                     /EC_number="5.1.99.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate 2'-epimerase"
                     /protein_id="HAP3134230.1"
                     /translation="MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADK
                     ARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDK
                     LHALRYADSVSMTLSWQR"
     gene            33330..34223
                     /locus_tag="IT892_000992"
     CDS             33330..34223
                     /locus_tag="IT892_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family protein"
                     /protein_id="HAP3134231.1"
                     /translation="MKIVITGGTGLIGRHLIPRLLDLGHQITVVTRNPQKASSVLGPR
                     VTLWQGLADHSNLNGVDAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINAS
                     DTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
                     LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRG
                     PFNMVSPYPVRNEQFAHALGHALHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRL
                     EEAGFAFRWYDLEEALADVVR"
     gene            complement(34271..35173)
                     /locus_tag="IT892_000993"
     CDS             complement(34271..35173)
                     /locus_tag="IT892_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HAP3134232.1"
                     /translation="MTISTTSTPHDAVFKSFLRHPDTARDFIDIHLPAPLRKLCDLTT
                     LKLEPNSFIDEDLRQYYSDLLWSVKTQEGAGYIYVVIEHQSKPEELMAFRMMRYSIAA
                     MQNHLDAGYKELPLVIPMLFYHGCRSPYPYSLCWLDEFAEPAIARQIYSSAFPLVDIT
                     VVPDDEIMQHRKMALLELIQKHIRQRDLLGLVDQIVSLLVTGNTNDRQLKALFNYVLQ
                     TGDAQRFRAFIGEIAERAPQEKEKLMTIADRLREEGRNDGLILGKREEALRIAQEMLD
                     RGLDRELVLMVTRLSPDDLIAQSH"
     gene            complement(35370..36143)
                     /gene="hisP"
                     /locus_tag="IT892_000994"
     CDS             complement(35370..36143)
                     /gene="hisP"
                     /locus_tag="IT892_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="HAP3134233.1"
                     /translation="MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGK
                     STFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFN
                     LWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQR
                     VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHV
                     STHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFLKGSLK"
     gene            complement(36151..36867)
                     /locus_tag="IT892_000995"
     CDS             complement(36151..36867)
                     /locus_tag="IT892_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3134234.1"
                     /translation="MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFL
                     AIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTEFLNAFFRSGL
                     NCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIAL
                     PAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLI
                     SLFRRAEKRWLQHVKPSSTH"
     gene            complement(36864..37550)
                     /locus_tag="IT892_000996"
     CDS             complement(36864..37550)
                     /locus_tag="IT892_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311219.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP3134235.1"
                     /translation="MLYGFSGVILQGALVTLELAISSVVLAVIIGLIGAGGKLSQNRL
                     SGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNTVTEAMGVGQIDIDPMVAGIITLGF
                     IYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV
                     ILKSTALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLVLERR
                     YSVGVKRADL"
     gene            complement(37640..38422)
                     /gene="hisJ"
                     /locus_tag="IT892_000997"
     CDS             complement(37640..38422)
                     /gene="hisJ"
                     /locus_tag="IT892_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="HAP3134236.1"
                     /translation="MKKLVLSLSLVLAFSSATVAFAAIPQNIRIGTDPTYAPFESKNS
                     QGELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQE
                     IAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
                     SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTG
                     MGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG"
     gene            complement(38643..39425)
                     /gene="argT"
                     /locus_tag="IT892_000998"
     CDS             complement(38643..39425)
                     /gene="argT"
                     /locus_tag="IT892_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="HAP3134237.1"
                     /translation="MKKSILALSLLVGLSAAASSYAALPETVRIGTDTTYAPFSSKDA
                     KGDFVGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQE
                     IAFSDKLYAADSRLIAAKGSPIQPTLDSLKGKHVGVLQGSTQEAYANETWRSKGVDVV
                     AYANQDLVYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGSSVKDKKYFGDGTG
                     VGLRKDDAELTAAFNKALGELRQDGTYDKMAKKYFDFNVYGD"
     gene            complement(39691..40260)
                     /locus_tag="IT892_000999"
     CDS             complement(39691..40260)
                     /locus_tag="IT892_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAP3134238.1"
                     /translation="MKRLIVGISGASGAIYGVRLLQVLRDVADVETHLVMSQAARQTL
                     SLETDFSLREVQASADVTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDG
                     LLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
                     DVINQTVNRVLDQFAITLPEDLFARWQGA"
     gene            complement(40355..41872)
                     /gene="purF"
                     /locus_tag="IT892_001000"
     CDS             complement(40355..41872)
                     /gene="purF"
                     /locus_tag="IT892_001000"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAP3134239.1"
                     /translation="MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFR
                     LRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHN
                     GNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAAT
                     NRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLG
                     FDFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSAR
                     VNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRT
                     FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVY
                     LASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIEAVRAE
                     NPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQNEVENLEMHNEG"
     gene            complement(41909..42397)
                     /gene="cvpA"
                     /locus_tag="IT892_001001"
     CDS             complement(41909..42397)
                     /gene="cvpA"
                     /locus_tag="IT892_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="HAP3134240.1"
                     /translation="MVWIDYAIIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHY
                     YTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGV
                     CFGALRGVLIVAAILFFLDSFTGVSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
                     RA"
     gene            complement(42656..43306)
                     /gene="dedD"
                     /locus_tag="IT892_001002"
     CDS             complement(42656..43306)
                     /gene="dedD"
                     /locus_tag="IT892_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="HAP3134241.1"
                     /translation="MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLV
                     PKAGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPATIAANNTEFEPEPA
                     PVVPPKPKPVEPPKPKVEAPPAPKPVVEEKAAPTGKAYVVQLGALKNADKVNEIVGKL
                     RGAGYRVYTSPSTPVQGKITRILVGPDASKDKLKGSLGELKQLSGLSGVVMGYTPN"
     gene            complement(43296..44564)
                     /gene="folC"
                     /locus_tag="IT892_001003"
     CDS             complement(43296..44564)
                     /gene="folC"
                     /locus_tag="IT892_001003"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAP3134242.1"
                     /translation="MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGV
                     LKPAPFVFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPE
                     SAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVD
                     ADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKSA
                     LLQRRGVEWNYSVTDHDWAFSDAHGTLENLPLPLVPQPNAATALAALRASGLEVSENA
                     IRDGIANAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLH
                     DKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADA
                     KAEDTVLVCGSFHTVAHVMEVIDARRSGGK"
     gene            complement(44634..45548)
                     /gene="accD"
                     /locus_tag="IT892_001004"
     CDS             complement(44634..45548)
                     /gene="accD"
                     /locus_tag="IT892_001004"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HAP3134243.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLE
                     VCPKCDHHMRMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKET
                     GEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFS
                     ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNI
                     AEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAK
                     LMNLPAPNPEAPREGVVVPPVPDQEPEA"
     gene            complement(45704..46363)
                     /locus_tag="IT892_001005"
     CDS             complement(45704..46363)
                     /locus_tag="IT892_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HAP3134244.1"
                     /translation="MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLV
                     VTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGDKLFS
                     NPDSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
                     VIGALLWVLLFTYAGYFFGTLPFIQSNLKLMIVGIIFVSILPGVFEFIRHKRAAARAA
                     K"
     gene            complement(46446..47258)
                     /gene="truA"
                     /locus_tag="IT892_001006"
     CDS             complement(46446..47258)
                     /gene="truA"
                     /locus_tag="IT892_001006"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP3134245.1"
                     /translation="MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALS
                     QVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKA
                     VPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGEND
                     FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHN
                     QPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD"
     gene            complement(47258..48271)
                     /locus_tag="IT892_001007"
     CDS             complement(47258..48271)
                     /locus_tag="IT892_001007"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAP3134246.1"
                     /translation="MSEGWNIAVLGATGAVGEALLETLAERQFPVGEIYALARNESAG
                     EQLRFGGKTITVQDAAEFDWTQAQLAFFVAGKEATAAWVEEATNSGCLVIDSSGLFAL
                     EPDVPLVVPEVNPFVLTDYRNRNVIAVPDSLTSQLLAALKPLIDQGGLSRISVTSLIS
                     ASAQGKKAVDALAGQSAKLLNGIPIDEEDFFGRQLAFNMLPLLPDSEGSVREERRIVD
                     EVRKILQDEGLMISASVVQAPVFYGHAQMVNFEALRPLAAEEARDAFAQGEDIVLSEE
                     NEFPTQVGDASGTPHLSVGCVRNDYGMPEQVQFWSVADNVRFGGALMAVKIAEKLVQE
                     YLY"
     gene            complement(48337..49473)
                     /gene="pdxB"
                     /locus_tag="IT892_001008"
     CDS             complement(48337..49473)
                     /gene="pdxB"
                     /locus_tag="IT892_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HAP3134247.1"
                     /translation="MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVR
                     SVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSS
                     LLMLAERDGFSLRERTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRS
                     LDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALL
                     TCLNEGQKLSVVLDVWEGEPELNVELLKKVDIGTPHIAGYTLEGKARGTTQVFEAYSK
                     FIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPG
                     EFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR"
     gene            49572..50567
                     /locus_tag="IT892_001009"
     CDS             49572..50567
                     /locus_tag="IT892_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulator Flk"
                     /protein_id="HAP3134248.1"
                     /translation="MIQPISGPPPGQPPGQGDNLPSGAGNQSLSSQQRTSLESLMTKV
                     TSLTQQQRAELWAGIRHDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQ
                     LGEYLRLGNNRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREAT
                     DRPLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWL
                     QARQTLSQQNTPTLESLQMALKQPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDIL
                     NQLYQRRVKGIDPRDMQPLLNPFPPMMDTLQNMATRPALWILLVAIILMLVWLVR"
     gene            complement(50564..51742)
                     /locus_tag="IT892_001010"
     CDS             complement(50564..51742)
                     /locus_tag="IT892_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose transporter"
                     /protein_id="HAP3134249.1"
                     /translation="MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHH
                     ELGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAA
                     ILPVSAPFKFALLVVGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
                     LAVGAPLGLLIHSHYGFAALALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLI
                     WKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRF
                     GGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQ
                     VRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
                     "
     gene            complement(52018..53238)
                     /gene="fabB"
                     /locus_tag="IT892_001011"
     CDS             complement(52018..53238)
                     /gene="fabB"
                     /locus_tag="IT892_001011"
                     /EC_number="2.3.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase I"
                     /protein_id="HAP3134250.1"
                     /translation="MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGM
                     RSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLI
                     AGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSIS
                     SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKA
                     SRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEG
                     AVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHS
                     LGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGF
                     GGTNATLVMRKLKD"
     gene            53397..55403
                     /gene="mnmC"
                     /locus_tag="IT892_001012"
     CDS             53397..55403
                     /gene="mnmC"
                     /locus_tag="IT892_001012"
                     /EC_number="1.5.-.-"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416827.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmD/FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HAP3134251.1"
                     /translation="MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLG
                     GNQLEARFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQAQLQRLHFISFEK
                     FPLTRADLALAHQHWPELAPWAEQLQAQWPMPLPGCHRLLLDEGRVTLDLWFGDINEL
                     TSKLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRR
                     GLQDAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSAPWFNRTGSSKREAAIIGGGIAS
                     ALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFAR
                     QFYDQLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPEELAVAVEANAVEQITGVT
                     TNCSGITYPEGGWLCPAELTRNVLELAQQQGLQIHYQYQLQDLSRKDDCWLLNFAGDQ
                     QATHNVVVLANGHQISGFSQTSTLPVYSVAGQVSHIPTTPELAKLKQVLCYDGYLTPQ
                     NPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDVSDKEARCGV
                     RCATRDHLPMVGNVPDYEATLVEYASLAEKKDEAVSAPVYDDLFMFAALGSRGLCSAP
                     LCAEILAAQMSNEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG"
     gene            complement(55459..55737)
                     /locus_tag="IT892_001013"
     CDS             complement(55459..55737)
                     /locus_tag="IT892_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcL family protein"
                     /protein_id="HAP3134252.1"
                     /translation="MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELES
                     GDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWENLFQQASQQ"
     gene            complement(55771..56319)
                     /locus_tag="IT892_001014"
     CDS             complement(55771..56319)
                     /locus_tag="IT892_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P hydroxylase"
                     /protein_id="HAP3134253.1"
                     /translation="MNSTHHYEQLIEIFNSCFADDFNTRLIKGDDEPIYLPADAEVPY
                     NRIVFAHGFYASAIHEISHWCIAGKARRELVDFGYWYCPDGRDAQTQSQFEDVEVKPQ
                     AFDWLFCVAAGYPFNVSCDNLEGDFEPDRVVFQRRVHAQVMDYLENGIPERPARFIKA
                     LQNYYHTPALTAEQFPWPEALN"
     gene            complement(56319..57128)
                     /locus_tag="IT892_001015"
     CDS             complement(56319..57128)
                     /locus_tag="IT892_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HAP3134254.1"
                     /translation="METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALM
                     AAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSGALLVQ
                     YVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFG
                     PAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVG
                     QFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAKLLYDSHGQEILHWLGIN"
     gene            complement(57128..57952)
                     /gene="mepA"
                     /locus_tag="IT892_001016"
     CDS             complement(57128..57952)
                     /gene="mepA"
                     /locus_tag="IT892_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="HAP3134255.1"
                     /translation="MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGC
                     IVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLSLGTVLIGDMGMPA
                     GGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVPTLWKPEI
                     FSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPA
                     DSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI"
     gene            complement(57956..59041)
                     /gene="aroC"
                     /locus_tag="IT892_001017"
     CDS             complement(57956..59041)
                     /gene="aroC"
                     /locus_tag="IT892_001017"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAP3134256.1"
                     /translation="MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHD
                     LDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVF
                     RPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
                     GDIPLEIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGL
                     GEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGI
                     LGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEA
                     MLAIVLMDHLLRQRAQNADVKTDIPRW"
     gene            complement(59076..60008)
                     /gene="prmB"
                     /locus_tag="IT892_001018"
     CDS             complement(59076..60008)
                     /gene="prmB"
                     /locus_tag="IT892_001018"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAP3134257.1"
                     /translation="MDKIFVDEAVNELQTIQDMLRWSVSRFSAANIWYGHGTDNPWDE
                     AVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGH
                     EFYVDERVLVPRSPIGELINNKFAGLISKQPQHILDMCTGSGCIAIACAYAFPDAEVD
                     AVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSD
                     LPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDV
                     PFTWLEFDNGGDGVFMLTKEQLLAAREHFAIYKD"
     gene            60174..60725
                     /gene="smrB"
                     /locus_tag="IT892_001019"
     CDS             60174..60725
                     /gene="smrB"
                     /locus_tag="IT892_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease SmrB"
                     /protein_id="HAP3134258.1"
                     /translation="MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPV
                     KRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHG
                     LTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
                     EYGGDAALLVLIEVDEWLPPELP"
     gene            complement(60795..61658)
                     /locus_tag="IT892_001020"
     CDS             complement(60795..61658)
                     /locus_tag="IT892_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001520950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2544 domain-containing protein"
                     /protein_id="HAP3134259.1"
                     /translation="MKIMRWILGLLISLFFSTAVQANVIVATMYTPIGYASYSTKITY
                     YLDVLTPDSVNHGVYETPNNTGLITGWIPLKSWTGPGPAPSLKVISMTAISQSSCPGL
                     AEYDSRAQRTMWTCYEIRMEVWKEDSSVHGCPWLVSTHADSIDLIDPAPGTYSGRTVS
                     NSSCPPIPLGPYDVSWNESRVVHDKTLALQSTGGIIEKTLSTYLMKDGKLCDGSKFGD
                     TDDRGAYCRWVSQMLTFTSSGCDNAKVTVTPNRHPITDKELHDMVLRVDTTSRQPIDS
                     TCRFQYVLNML"
     gene            complement(61660..62205)
                     /locus_tag="IT892_001021"
     CDS             complement(61660..62205)
                     /locus_tag="IT892_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3134260.1"
                     /translation="MNKLKKYQCIRVQTFLLGGVLVLASHSALAANNLHFYGNLMSKT
                     CTPVEQAGTLAEVQFANISHKDLMVRGQSDRVPVVFRLKDCRGPAQYSVKVTLTGTED
                     SGQPGFLALDDTSGAQGVGIGMETTDGTAVAINNTTGVTFVLNDGNNSLNFRAWLQAK
                     EGRDVTPGNFTAQLTATFEYI"
     gene            complement(62202..62681)
                     /locus_tag="IT892_001022"
     CDS             complement(62202..62681)
                     /locus_tag="IT892_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001600244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3134261.1"
                     /translation="MKRLSLILLSAFCTITHAAPEDITFTGTLIEPPVCTVSNGDDIE
                     IQFIDVIIDNIDGVNYRKDVPYQITCDPDITDDAWVMTLTWTGTQTNYNDAAIQTDVT
                     GLGIELQQNGQPFKLNTPLNVTPANLPKLKAAPVKASDATLTDGNFSAYATLQVDYQ"
     gene            complement(62678..63169)
                     /locus_tag="IT892_001023"
     CDS             complement(62678..63169)
                     /locus_tag="IT892_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000826021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3134262.1"
                     /translation="MKRLLLAGLGGVLLTGSALAGETKSVPLTLRVLVDPPPPCTVKG
                     SNVDFGDVIIKKINGTEYRKDAGYTLNCANSLSDDLQMQFKGTTTTINGETVLSTGIT
                     GFGIRIENAADNSLFAIGDNTWTPFSVSSQPQLKAVPVKQNGVTLTGAQFNASMTMVV
                     DYQ"
     gene            complement(63185..63934)
                     /locus_tag="IT892_001024"
     CDS             complement(63185..63934)
                     /locus_tag="IT892_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HAP3134263.1"
                     /translation="MTKYLSAKTLTTVLSLLAATVSFSTQASVTPDRTRLIFNESDKS
                     ISVTLRNNDPKLPYLAQSWIEDEKGVKISSPLAVLPPVQRIEAMMNGQVKIQGLPDIH
                     KLPADRESMFYFNVREIPPKSNKSNTLQIALQTRIKLFWRPKALEKNTTQNPWQHKVT
                     LTRNGQEFTVNNPTPYYVIFSNASAQKNGNPAAGFSPIVMSPKTSAPLNVKMGSVPVL
                     TYVNDYGARMPLFFTCNGNSCQVDEEQSRKG"
     gene            complement(63954..66593)
                     /locus_tag="IT892_001025"
     CDS             complement(63954..66593)
                     /locus_tag="IT892_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HAP3134264.1"
                     /translation="MPEHSFLRLRGLSWWIALAISGSPFNALADDTIQFDGRFLDLKG
                     NTKIDLGRFSQKGYVEPGKYNLRVHVNNQPLPDDYDIYWYATENDPNKSYACLSPELV
                     AQFGLKEDIAKNLQWIRDGQCLNTALLAGTEISGDLGQSALLVSVPQAYLEYTDSEWD
                     PPSRWDDGIPGLIADYSINAQTRHENGGDDTNDICGNGTVGVNVGPWRLRADWQSDYQ
                     HTRSNDDGDTDDSGTQKNWEWSRYYAWRALPSLKAKLSLGEDYLNSDIFDGFSYIGGS
                     ISTDDQMLPPNLRGYAPDISGVAHTTAKVTVTQMGRVIYETQVPAGPFRIQDIGDSVS
                     GTLHVRIEEQNGQVQEYDVSTASMPFLTRPGQVRYKVTMGRPQNWDHQVAGSFFSGGE
                     ASWGIANGWSLYGGALADENYQSAALGLGRDLALLGALAFDVTHSRVQLDDNSVYGNK
                     TLDGNSYRVSYAKDFDELNSRVTFAGYRFSEKNYMTMSEYLDANDDDRARTGNDKEMY
                     TVTYNQNFTDARVSVYLNYSHHTYWDRQDQTNYNMMLSHYFNLGSLRNLSVSLTGYRY
                     EYDKSADKGVYLSLSLPWGDNSTISYNGNYGSGADSNQVSLYHRIDDASHYTLSAGTS
                     ENHSSVDGYYSHDGTLAKVDLSANYHEGQYTSAGISLQGGATLTAHGGALHRTQNMGG
                     TRLLIDADGVANVPVEGNGSAVYTNMFGKAVVADVNDYYRNQAYIDLNKLPENAEATK
                     SVVQATLTEGAIGYRKFAVISGEKAMAVLRLQDGSHPPFGAEVKNDNQQQVGLVDDEG
                     NVYLAGVKPGEHMTVFWEGESHCDISLPDPLPNDLFNGLLLPCQQKGGSSPVIPHDIQ
                     PVIQEQTQQVTPMEPPMSVSSNQ"
     gene            complement(66677..67243)
                     /locus_tag="IT892_001026"
     CDS             complement(66677..67243)
                     /locus_tag="IT892_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3134265.1"
                     /translation="MSKFVKAAVATAMLMGALTSASVVAAGNNGTVRFYGTIEDSPCS
                     IVPDDHKLEVDMGSIGTGSLTGGKTTTPKDFQIRLQDCNFNTETTMATTFTGNPYSTN
                     ADNYSLSNMDNGTEIPNVSLVIGDQHGTGYALGAEIKQPIVKDSSTGKGKPKQTLNFK
                     AWLVGETDAVTPTPAPFETLTTFQITYL"
BASE COUNT        16715 a        18312 c        16918 g        15652 t
ORIGIN      
        1 ttccttttat tattttttac caaccctggg tcaatgcatt accgccaacg ccccgacacg
       61 caagtcctga gcaattagaa aaaacagttc gttatcttac acaaactgtg catccccgta
      121 gtgccgacaa tattgataat ctgaaaaggt ccgcagagta tataaaagag gtctttgtca
      181 gtagcggtgc cagagttacc gcgcaggacg tccccattac gggtggcccc tacaaaaaca
      241 ttgttgctga ttatggtcct gccgatggac cgctgattat tattggtgcg cactatgact
      301 ctgccagcag ttatgaaaac gatcaattga cctatacgcc gggcgcggat gataacgcca
      361 gcggcgtggc aggattactc gaactggcac gtttgttaca gcagcaagta ccgaaaactg
      421 gcgtgcagct ggtcgcctat gcgtcggaag aaccgccctt ctttcgtagc gatgaaatgg
      481 ggagcgcggt acatgcagct tcgcttgagc gtccagtgag attaatgata gcgctggaga
      541 tgattggcta ttacgactct gcgcctgata gtcagaatta cccttacccg gcaatgtcct
      601 ggctttatcc cgatcgggga gactttattg ccgtggtagg cagaatgcag gatatcaacg
      661 ccgttcgtca gctaaaagcg gcattgttgt catctcagga tttatctgtt tattctatga
      721 atgccccagg gtttattccc ggtattgatt tctctgatca ccttaattat tggcaacacg
      781 atattcccgc cgtaatgatt accgacaccg ctttttatcg taataaacaa taccacttgc
      841 ccggtgatac cgcagacaga ttgaattatc agaaaatggc tcaggtagtg gatggggtta
      901 taactttgtt atacaacagt aaataataaa aatttctcga ggcgggtcca gaaaaagcga
      961 catgtacatt ttattttccc tcgtctgttt taagatgcga aacatgaaat tcaacggagg
     1021 aaaataaaat gggaatgatt ggctattttg cagaaattga ctcagaaaag attaaccaac
     1081 tgcttgagtc tactgaaaaa cccttaatgg acaatattca tgacacgctt tcaggattac
     1141 gccgactgga tattgataaa cgctgggatt ttttacattt tggcctgaca ggcacctctg
     1201 cttttgatcc cgcgaagaat gatccgctga gtcgtgccgt gcttggtgaa cacagcctcg
     1261 aagatggcat agatggcttc ctgggattga cctggaatca ggagttagcc gcgacaatcg
     1321 atcgcctgga atcactggat cgaagtgagc tgcgtaaaca gttttccatt aaacgactca
     1381 atgaaatgga gatttaccct ggtgtgactt tttcagaaga gttagagggg caactctttg
     1441 cttcgatcat gcttgatatg gaaaagctga ttagtgcgta tcgacgtatg ctgcgacaag
     1501 ggaatcatgc gctgacggtt attgttgggt gatggtgtca gggcaccaaa aaaaaccgcc
     1561 gaacatgtcg gcggctttct gacttacaaa ctgacagctt acatcagcgg catggctaac
     1621 cgcacaatgc taatcagcgg ttgtggccat acacccagca ccagtaccaa cagtgcagag
     1681 atcagcacca cgataccacc cgcgctgtac tgccagtttg atggtgcatc gcgacccggt
     1741 tgttccgggg cgtgcaggta taagctcacc gccacgcgca ggtagtagta gaggccgatt
     1801 gccgaaccga caaccacggc acccaccagc caccacaagt gcgcctggac accgaccgcc
     1861 agcacgtaga acttaccaat aaagcccagc gtcatcggga taccggccag agacagcatc
     1921 atcaccgtca tcaccgccgc gaggatcgga cgatgccaga acagtccgcg gtaagagaac
     1981 agggaatcag catccgggcc acgatacggg ctggacatca ggctgaccac gccgaacgcg
     2041 ccaaggctgc tgaacagata accggccagg taaaccccta ccgcttccat cgacatctcg
     2101 ccggtttgca gcgcaatcag cgccaccagc agatagccga ggtgagagat agatgagtaa
     2161 ccgagcagac gtttgatatt ggtctggctc aacgccatca ggttaccgaa gatgatagag
     2221 gcaaaggcga taatcgccag caccacgcga atcgcttcgc tgtcacccac cggtgcgtag
     2281 aggaacagac gcatcaccac gccgaagata gcgattttgc tcgccgtcgc caggaaagtg
     2341 gaaaccggcg caggcgcgcc ctggtatacg tctggcgtcc acaggtggaa cggcaccaga
     2401 gagagtttga agccgaggcc aacaatcatc agtccgaaac ctgccagcaa cagcggctcg
     2461 ttgagcatac cgtcgccgag gtttttaccc agcgcgacaa acgacaggtc gccagactgc
     2521 gcatacacca gcgccatacc aaacagcagg aaagaagacg ctgcggcaga gagaatggtg
     2581 tatttgatac tggcttccag cgaacgtttc tggcggaaag cgtaaccgac caggccaaac
     2641 agcggcaaag agatcagttc gataccgagg aacagagacg ccagatggtt ggcattcgcc
     2701 agcaggatcc cgcccagcgc ggcaattaac accaacaggt agaactcatc cttgttgtcg
     2761 ttatagcctt caagccacgg gtaggcgaaa gtacaggtgg cgaggctcgc caacaatacc
     2821 agcccggtgt aaagcatggc gaaaccatca acgcgcatca gcggcgtaac gtccatagcg
     2881 cccgcctggc cgacaaacca gagcgaaacc agcgccgcgt taagcccaat aaccgagagc
     2941 gtagcgttga ggaaatgatt gcgtcgccac gcaatggaga gcatcacaac caccaccgtc
     3001 aagccgacga tcagcaacgg tagcagtgcg atcaggtttt gtggagttat tgtcatggcg
     3061 atttacggcc ttgtagtagt aacggaatta acaaaccact gctggatatt gccaatcgcg
     3121 gaatgcgagg tatccagaat cggctgcgga tagaagccca gcagtaccag cagcaccacc
     3181 agcaacagga tcataaacag ctcacgcagc gacatccctg gcagttcctg gctggcaatc
     3241 tggcttttcg ctttaccgaa gtaagcgcga tgcaacatcg ccagcgaata aacagatgca
     3301 aagaccagcc caaaggtaga gataacggta atcaccggga caacctggaa gctgccgaac
     3361 agaatcataa attcgccgac gaagttaccg gtgccaggca tcccaagcgt tgccaccgca
     3421 aagaacagcg acagtgctgg cagccatttc atcttgctcc acagaccgcc catcatgcgc
     3481 atgtcgcggg tatggatacg ttcataaagc tgaccgcaga gaataaacag acccgccgcc
     3541 gacaagccgt gcgcaatcat ctggattacc gcgccctggt aggccaactg gctgccggta
     3601 tagatagcaa tcagcacgaa gcccatgtgg gaaaccgagg tgtaggcgat cagacgtttg
     3661 atatcggtct gggcgaaggc catccacgca ccgtagaaga tgccgataac acccagccac
     3721 atagcgattg gcgcgaactc tgccgacgcg ttcgggaaca gcggtaggga gaaacgcagc
     3781 agaccgtaag cggcggtttt cagcaagatc cccgcgaggt caacggaacc ggcggttgga
     3841 gcctgtgagt gcgcatccgg cagccagcca tgcagcggaa ccaccggcat tttcaccgca
     3901 aatgcgatga agaagcccag catcagcaaa tattccacgc cgttagacat tggcgtattc
     3961 agcagctctt catagttgaa ggtccagacg ccggtcgcat tgtagtgaac aaaaaccagc
     4021 gccaggatgg cgatcaacat caccagacca ctcgcctggg tgtaaatgaa gaacttggtt
     4081 gccgccgtga tacgcgtttt accgtcagag gctttatgcc cccacagtgc gatcaggaag
     4141 tacatcggca ccagcatcat ttcccagaag aagaagaaca ggaacatgtc gatggcaagg
     4201 aacacgccga taacgccgcc caggatccac atcaggttga ggtggaagaa gccctggtat
     4261 ttttcgatct ctttccacga acagagtacc gccagcacac cgagcagacc ggtcagcacg
     4321 accatcagca gcgatagccc gtcaatggcg agatggatag agataccaaa acgcgggatc
     4381 cacggcatgt cgaattcaga ctgccactgc ggaattccgg cggattgcgt cagtgaataa
     4441 ccgccctgca accacagttg cagcgacagc gccagcgtca atcccatggt gatcagcgcg
     4501 atccagcgcg gcaccttgac gccaaagcgt tcggtctgcc agcacaggaa gccgccgata
     4561 aaggggatta gtattaacca gggtaataac atagctaagt atgtccctta tatttactcc
     4621 tgctcaggct atctcactcg ccagcccgaa tcccggcagt gctcgcaatc ctcacgtact
     4681 taagtacgct ccggttgctg tgcgctggcg gtatccggtc tgacttcgcc gatgacgcct
     4741 gtacttcagg aacagttacc taaaatttat tcttagttca cagacccggc gcaacgccgg
     4801 gtatattcac tcagccaaca actcaacgca gtaccatcaa cagtgccagc accacgaccg
     4861 caccgatgct catggatgcc acataccagc gcagataacc gttctcgctt aacagcagac
     4921 ctttacctgc aaagcgggaa aggacagccg ggatgttcat cattgagttc agcggatcgc
     4981 gtttcagcaa ccaggcaata cccaggaacg gcttgacgaa cactttgtca tacagccagt
     5041 caaatcccca ggcgttgtac caccaggtgc ccagcagacg gcccggcgca ctgttggcga
     5101 tggaggtcac cagagtacgt ttacccagcc acagccaggc tgccagcaga atgccgacca
     5161 ccgcgaccac gccagaggta atttccaggg tcaacatgct gccgtgcgcc agctccgtcg
     5221 tttgcggaag cacgccctgc agcggcggta caatcagtgc gccaacgaag gtggaaagga
     5281 tcagcagcac aatcagcggc aggctgtgag ttaccccttt cacggcgtga gcgtgaattt
     5341 gttcttttcc gtggaagacg atgaaaatca tacggaaggt gtagagcgag gtcataaacg
     5401 caccgaccag acctgccacc atcagattga tatgaccatt cgccatcgca cccgcgagga
     5461 tctcatcctt actgaagaag cccgcagtga ccagcggcag tgccgacagg gctgcgccgc
     5521 ccaccaggaa gcagagataa accagcggaa tagatttacg cagaccgccc atcttgaaga
     5581 tgttctgttc gtgatggcag gccagaatga cggaaccgga tgccaggaac agcagcgctt
     5641 taaagaacgc gtgagtcatc aagtggaaaa tcgccgcatc ccatgcctgt acgccaagcg
     5701 cgaggaacat gtagccaatc tggctcatgg tagagtaagc gagaacacgt ttgatatcgg
     5761 tctgtaccag cgcggcaaaa ccggccagca gcagcgtaac cgccccaaca atgcccacca
     5821 gatgcagaac ttccggcgtc atcaggaaca ggccgtgggt acgggcgatc aggtagacac
     5881 ccgcggttac catggttgcg gcgtggatca gcgcggagac aggcgtcggg cccgccatcg
     5941 cgtcggcaag ccatgtctgc aacggcaact gcgcagattt accgaccgca ccgcccagca
     6001 gcatcagcgt cgcccacatc agcatgttat tgccgtcagc aaagtgcgct ggtgccagtt
     6061 ccaccatttc gcggaagttc agggtgccca gttcgttgta aagaatgaac agcgcgaaag
     6121 cgaggaacac gtcacccaca cgggtcacga cgaatgcctt cattgccgct gcgccattct
     6181 tcggatcggt gtaatagaaa ccgatcagca gataggagca caggcccacc ccttcccagc
     6241 cgaggtacat cagcagcagg ttgtcggcaa gcaccagaac taccatgctg gcgatgaaca
     6301 ggttggtgta agcgaagaag cgagagtagc cctcttcacc gcgcatatac caggaggcgt
     6361 acatgtgaat aaggaaaccc acaccagtga ccaccgagag catggtcagc gacaggccgt
     6421 ccagcaccag gttaaaaccg atgttaaagt cacctaccga catccacgtc cacagcggct
     6481 ggctatatgc ctgctcgccg ttagcgaaga agtcaacgcc gataaaagcg gttaccagcg
     6541 ccgccaagcc cacagagcca acgcccacga tcgccgagac gttttcagac cagcgcccac
     6601 gggagaacgc cagcaggacg aagccaatca atggcaaaat aatggttaag gcaagcatgt
     6661 tcatccgcgc atctcactta ctgaatcgat gttcaggttc tggcgacgac ggtgaagttg
     6721 cagcagcagt gcaaggccga tacttgcttc tgccgccgcg aggctgatgg cgagaatgta
     6781 catcacctga ccgtcggtct ggccccagta gcttccggcg accacaaagg ccagcgcaga
     6841 ggcgttaatc atgatttcca gaccaatcag cataaacagc agattgcgac ggataaccag
     6901 accggttaag ccaagaacga ataagattgc cgcgaggatc agtccatgtt gtaaggggat
     6961 catgcgtgct cctccgtttt tcttttcgcg ctgtcgtctt tacgattgct cagcacttca
     7021 cccgctcgct cttcacgacc aacgtggaag gccacaacca gacccgcgag cagcagcata
     7081 gaagccagtt ccaccgccag tacgtaaggc ccgaacagcg taatacccac tgctttagca
     7141 ctgattggcg taccgtcgat accctgatcg ttaacaccaa gaatggcgta aacaatcacc
     7201 accagcatga tggccgacaa aattgccgga ccaatccaca cctgcggttt cagccactgg
     7261 cgttcctgtt caatttctga accgcccagg ttgagcatca tcaccacgaa cacgaacagc
     7321 accataatgg cacccgcgta gacaataatt tccagcgcac cggcaaagta agcgcctagc
     7381 gagaagaaca ccccggaaat cgccagcagc gaaataatca ggtacagcag tgcgtgtacc
     7441 ggattggtat gggtgatcac tcgcaaggtc gcaagtatgg ctatcaggcc acagatataa
     7501 aaagcgaact ccattgcccc tctccttacg gtaacaggct cttgacgtcg ataggcttgg
     7561 cttcgttctc tgcttcgccc ttatctttgc cgtcgattgc catacctgcc atccggtaga
     7621 agttatattc cgggtatttg cccggaccgg agatcagcag atcctctttc tcgtaaacca
     7681 gatcctggcg cttgtattcc cccatttcga aatccggggt taactgaatc gccgtggtcg
     7741 gacaggcttc ttcgcacaga ccacagaaaa tgcagcgtga gaagttgatg cggaaaaatt
     7801 ccggatacca gcgaccgtct ttggtttctg ctttttgcag cgagatacag ccgaccgggc
     7861 aggctaccgc gcagaggtta caggctacgc aacgctcttc gccgtccggg tcgcgggtca
     7921 gaacgatacg accacgataa cggggcggca gatagaccgg ctcttccggg tacattcgcg
     7981 tttcgcgttt ggcgaacgca tgcaggccga tcatccagat actacgaacc tgggtgccga
     8041 aacctactaa caattctttt aaggtcatgg tcttattgcc ccttattgcg cctgccagag
     8101 aatgacagcc gccgttacca gcaagttgat cagcgtcagc ggcaggcaga ttttccagcc
     8161 gaaggacatt acctggtcat aacgcggacg cggtaacgac gcacgaatca aaatgaacat
     8221 catcataaag aacgcggttt tcagcgcgaa ccagatgaat ggcggtaaca acgggccttg
     8281 ccagccaccg aagaacagcg tcaccatcag tgcagagatg gtcacaatcc cgatgtactc
     8341 acccacgaag aacagaccga acttcatacc ggaatattca atgtggtaac catccgccag
     8401 ttcctgctcg gcttccggct ggtcaaacgg gtgacggtga cacaccgcca cgcccgcgat
     8461 ggcaaaggta ataaaaccaa agaattgcgg gatgacgttc cacacatgcg cctggctgtt
     8521 aacgatgtcg gtcatgttga atgaaccggc ctgcgccacc acgcccatca gggaaagccc
     8581 gaggaacact tcgtagctca gagtctgcgc agaagcacgc atcgcaccca gcagcgagta
     8641 tttgttgtta cttgaccagc ccgcaaacag caccgcgtag accgccagac cggccatcat
     8701 caggaagaac aaaatcccga tgttcaggtc ggcaaccacc caacctgggc tgactggcac
     8761 aatcgcaaag gccagcagca gcgaggtaaa ggcaatcatc ggtgccaggg taaagatgac
     8821 gcgatccgag aatttcggga tccagtcttc tttaaagaac atcttgatca tgtccgcgac
     8881 cagctggagc gaaccgcccc agccaacacg gttaggtccg taacggttct ggaacagacc
     8941 cagcaggcga cgttcgccaa agctcatgaa tgccccacag gtgacaacca ccagcaggat
     9001 caccaccgct ttgaggatgg tcagcaggat ctcaatcagt tccggtgata tccaactcat
     9061 tgttgtgcct ccttgagatc ctcaagatgc gcgcccgcca gcaccggagc aatgccggac
     9121 atacccatcg gcaagcccac ctgccctgcc gtcagccctt cggcgatttc aaccggcagc
     9181 gtgaccgtgt tgccatcgta actaaaggag acgcgtgtac ccgcgttcac acccaacttc
     9241 gcggcatccg ctgggttgag tttgatgtac ggctgcggca tacggctctg gaagaccgga
     9301 gcacgctgtg acaattcatc gctgccaaac aggtggtaat acggcgcgat acgccatttc
     9361 ccgtcctgcg gctggaagcg tgccggtacg ctggtgaagt aatccagacc gttttcgctg
     9421 gtttcaaaca gacgcacgcc cggatcgcca aagcgcagtt tgccgcccac ttcgtcctgg
     9481 aatttgttcc acgcctgcgg ggagttccag cccggtgccc aggcaaacgg cacttgcgaa
     9541 cggtgcgcgg tcggctggtt gttaccttcc atcgagaagg tgaacatggt gtcaatatcc
     9601 tgcggctgac gcggctcatg aacgctgatg ttggcgcgca tggcggtacg accgctgtaa
     9661 cggtgtggtt cacgggccag tttctgtcca cggatacgga atgtcgcatc cggcgcagca
     9721 tctttgatac ctgccagctc cgggattttc gccacaacag cgtcaatcac atggtcgagc
     9781 tgcgtccagt ccacttcacg gctcagcagg gtgctgtgca gcgagtgtaa ccagcgccag
     9841 ctttccagca tgacagtttt gctgtcgtaa taggccggat cgtaaacctg gaagaaacgt
     9901 tgggcgcggc cttcgttgtt gatcaccgta ccgtcgcttt cagcaaagct ggcagcagaa
     9961 agcaccagat gggcgttttc cataatcgcc gtgcgttgat ggtcaaccac catcaccagc
    10021 ggcgctttcg ccagcgcagc attcacgcgg gtagcggaag cgtgacgatg cagatcgttt
    10081 tccagcacca ccaccgcgtc ggcgcgtccg gtttccagtt cggttaacgc ttcttcaagt
    10141 gatccaccgc ccataatgcc cagccccata ctgtttacag agcgagcaat catggtgata
    10201 ccgacgtcag cgccgcgacc tttcagggct ttcgccacgt tagccgcagc ctgaatcact
    10261 tcagcgctac cagcgttcgt cccggagata atcaacggtt tcttcgcacc cgccagagcc
    10321 tgcacgatga cgtcgatttt gctttgcagc tcaggttcga ttccgtcaac cgctggcgcg
    10381 gagttatcca gcgcatgggc gatggcaaaa cctaaacgcg cctgatcttc aaccggtgcg
    10441 cggtaagtcc acgccgcgat atcatccaga cgggtatcat caacgttggt aacaaacagc
    10501 ggatgcttcg cacgttgacc gatgttgagg attgccgcaa tctgccagtc agccactttc
    10561 tgtgctgccg ccatttcgcg cgctttacct ttcaccgcct gacgcactgc cagcgcgacg
    10621 cgcgcaccgg tctgggtaac gtcttcgccc agcaccagta ccgcatcgta agattcgatt
    10681 tcgcgcagtg ccggcgtata aatgccgcct tcacgcagca ctttcagcgc cagttgcaga
    10741 cgttcctgct caccgtgagc gataccggtg tagaagtttt cttcgcccac cagctcacgc
    10801 agcgcaaagt tgctttccac gctggcacgc ggagaaccga tgccgatcac tttcttcgac
    10861 tgacgcagaa tatctgctgc gccctgcatt gcctgttcgg cattgagggt aatgaaatca
    10921 tcgccacgac gctgtactgg ctgacgcgga cgatctttca ggttgacgta accgtaaccg
    10981 aaacgaccac ggtcgcagag gaagtagtgg tttactgtac cgttgtaacg gttttcgatt
    11041 cgacgcagtt cgccataacg ctcgccgggg ctgatgttac agccgatgga acattgctgg
    11101 cagatgctcg gcgcaaactg catatcccat ttacggttgt aacgctcgga gtgcgttttg
    11161 tcggtaaata cgccggtcgg gcaaatttcg accaggttac cggaaaattc gctttccagc
    11221 gtgccgtctt ccgggcgacc gaagtagacg ttgtcgtgtg caccgtaaac gcccaggtcc
    11281 gtgccgtcag cgtaatcttt gtagtaacgc acgcagcggt agcaggcgat gcagcggttc
    11341 atttcgtgag agatgaatgg ccccaaatcc tgattacggt gggtacgttt ggtgaaacgg
    11401 tagcgacgga agctgtgtcc ggtcatcacg gtcatatcct gaagatggca gttaccgcct
    11461 tcttcacata ccggacaatc gtgcgggtgg ttggtcatta accactcgac cacactttca
    11521 cggaactgtt tcgcttcttc atcgtcaatg gaaataaagg tgccatcgga agccggtgtc
    11581 atacaggaca tcaccaggcg accacgcgtg tcttccgcgt tttggtattg cttcaccgca
    11641 cactggcggc aagcaccgac gcttcccagc gccggatgcc agcaaaagta aggaatatca
    11701 aggcccagag acagacaagc ttccagcagg ttgtccgctc cgttgacctc gtattctttg
    11761 ccgtctacat gaattgtagc cattagcatg cttccagttt tctcagtcag agactgagcg
    11821 ttaatcgaaa ttcggttacc agcgctcttt cagcaggttc ggctgaatcc cattaatcaa
    11881 atgggtattg ctgaacggct gtttgattcc cgcctcaaat tcttcgcgga aatatttgat
    11941 ggcgctctgt aacggctcca ctgcaccagg tgcgtgggca cagaaagttt tacccgggcc
    12001 taagaatcga cacagttgct caagtgtttc gatatcgccc ggctgacctt cgccacgctc
    12061 cagcgcgcgc agaattttca cgctccacgg cagaccgtcg cggcacggcg tacaccagcc
    12121 acaggactca cgggcgaaaa actcttccag gttacgcacc agcgacacca tgttgatctc
    12181 atggtcaacc gccatcgcca gcgccgtacc cagacggctt cccgctttac cgatactttc
    12241 gaattccatc ggcaggtcaa ggtgcgcttc agtcaggaag tcagtacccg caccgcctgg
    12301 ctgccaggct ttgaatttca gaccgtcacg cataccaccg gcgtaatctt cgaggatctc
    12361 gcgagcggtg gtgccgaacg gcagttccca caggcccgga tttttcaccc gaccggagaa
    12421 gcccatcagc ttggtgccag catctttact tttcgagatg ttctgatacc actccacgcc
    12481 gttagcaagg atcgccggaa cgttacacag ggtttcgacg ttattgacac aggtcggttt
    12541 gccccatacg ccggaggttg ccgggaaggg gggtttcgag cgtgggttag cacgacgccc
    12601 ttccagggag ttgattaacg ctgtttcttc cccgcagatg tagcgccctg caccggtatg
    12661 gacgaacagt tcgaagtcga aacctgttcc cataatgttt ttgccaagca agcccgcttc
    12721 agtcgcttcg gcaatggcgc ggcgcagatt cactgccgct tcaatatatt cgccacgcag
    12781 gaagatgtag ccacggtaag ctttcagcgc aaacgcggag ataagcatac cttccaccag
    12841 caggtgcggc agttgctcca tcaacaggcg gtctttatag gtgcccggtt ccatttcatc
    12901 ggcgttacac agcaggtaac ggatgttcat ggattcgtct ttcggcatca ggctccactt
    12961 caggccagtc gaaaagcccg cgccgccgcg ccctttcaga ccagcgtctt ttacctgatt
    13021 aacgatttcg tccggagaca gcccggtcag cgccttacgc gccccttcgt aaccgttttt
    13081 gctgcggtat tcgtccagcc acactggctg tttgtcatcg cgcagacgcc aggtcagcgg
    13141 atgcgtttcg ggagtacgga taatgttttt catttatacc gctccagcag ttcagggatc
    13201 gcttccgggg tcagatgcgc gtgagtgtcc tcatcgatca tcatgtttgg ccctttatca
    13261 cagttcccca ggcagcaagt tggcagcagc gtaaagcgac cgtcaaatgt cgtttgccct
    13321 ggtttgatgt tcagcttttt ctcgagcgcc gcctgaatac cctgataacc gttgatatga
    13381 cagaccacgc tgtcgcaata acggatcaca tggcgaccaa ccggctggcg gaagatctgg
    13441 ctgtagaacg ttgccacgcc ttctacgtcg ctcgccggaa tacccagcac atcggcgatc
    13501 gcgtggatcg cgccatccgg cacccagcca cgctgcttct gaacgatttt cagcgcttca
    13561 atggacgccg cacgcgggtc ttcgtagtgg tgcatctcgt gctcaatcgc ttcacgctct
    13621 gccgcactca gctcaaaagc ctcagtttgt ggttgttgat tctcgtgcat aattagcggt
    13681 ccacatctga cataacaaaa tcgatactgc ccagataaac aatcaggtca gacaccaggc
    13741 tgccgcggat cgccgccgga atttgctgca aatgcgcata actcggcgta cggatacggg
    13801 tgcgataact catggtgcta ccgtcgctgg tcaggtagta actgttgatc cccttggtcg
    13861 cctcaatcat ctggaaagat tcattggctg gcatcaccgg accccacgac acttgcagga
    13921 agtgggtgat cagggtttcg atatgttgca acgtgcgctc tttcggcggc ggcgtggtca
    13981 gcgggtgatc cgctttgaac gggccttccg gcatgttgtt gaggcactgc tcaagaatgc
    14041 gcagactctg gcgcagctct tccactttca gcattacgcg ggtgtagcaa tcagaaacac
    14101 caccaccaac cgggatttca aagtcgaagt tttcatagcc agaatacgga cgcgccttac
    14161 gcacgtcgaa gtcgatcccg gtggcgcgca ggcccgcgcc agtggtgccc cactccagcg
    14221 cctctttcgc gccataggcg gcaacgccct gggaacgacc tttcagaata gtgttttgca
    14281 gcgccgcttt ctcgtaagac gccagacgtt tcggcatcca gtcgaggaac tcacgcagca
    14341 ggcgatccca gccacgcggc aggtcgtgcg ctacgccgcc aatacggaac cacgccgggt
    14401 gcatacggaa accagtgatt gcttccacca gatcgtaaat tttctgacga tcggtaaagg
    14461 cgaagaacac tggcgtcatt gcgccgacgt cctgaataaa ggtcgagatg tacagcaggt
    14521 ggctgttgat gcggaacagc tcagaaagca ttacgcgaat gacgttaacg cgatccggca
    14581 cggtgatccc ggccagtttc tctaccgcca gcacgtaagg catttcgtta acgcagccac
    14641 cgaggtattc gatacggtcg gtatacggaa tgtagctatg ccaggactgg cgctcgccca
    14701 ttttctccgc accacggtgg tggtagccga tatctggtac gcagtcgaca atctcttcgc
    14761 catcgagctg caaaacgata cggaaagcac cgtgcgccga cgggtggttc ggaccgaggt
    14821 tgaggaacat gaagtcctcg ttttcggtgc cgcgcttcat cccccactct tccggtttga
    14881 aggtcagggc ttccatctcc agatcctgtt tggctttggt cagctcaaac ggcgagaatt
    14941 cggtagcgcg cgccgggtaa tctttacgca gcgggtgacc tttccaggtt tgcggcatca
    15001 tgatgcggcg caggttcggg tgaccgtcga aagtaatgcc aaacagatcc caggtctcac
    15061 gctcatacca gttagcgttc gggaacagtt tggtgaaggt cggtacgtgc aggtcgtttt
    15121 ctgccagcgc caccttcaac atgatgtcgc ggttacgatc gatagaaatc agatggtaga
    15181 aaacggaaaa atccgcggca ggtaaccctt cgcggtgtgt gcgcagacgt tcgtccatgc
    15241 cgtgtaagtc aaacagcatg acgtaaggtt tcggcagttt ctttaagaaa tcgccaactt
    15301 ccagtaattg ttcacgcttg atccacacaa cgggaacccc ggtgcgagtc gcctgaacag
    15361 taaaggcatc cggcccaaaa cggttgcgca gttcgccaat caccggatca tcaagatgat
    15421 cgcgggtctg ccaggcgggt tcttgcgcgg ttaagtcggt catattgttc accattgcaa
    15481 atggtccgtg gtgactgtcg gcgcagtaag cttcgcgaaa tagatttagg aataagcgaa
    15541 gaaaaattcc tttgccgaca ggcgcaaatt aaatctcgtc aggtgtacgc aggttggtta
    15601 cggcaatgcg ttcaccgcgc ttgcgttcgc gctctgattg catattggcg cgataaacgc
    15661 cctgatcgcc aaccacccag gagagcggac gacgttcttt accgatagat tcctgcaaca
    15721 gcatcagtgc ctgcatgtac gcttcaggac gcggagggca gcccgggata tacacatcaa
    15781 ccgggatgaa tttatcgacg ccctgcacaa cggaataaat atcgtacata ccgccagagt
    15841 tggcacaggc acccattgag ataacccatt ttggctccag catctggtca tacagacgct
    15901 gaataaccgg tgccattttg gtaaagcagg ttcctgccac caccatcagg tcagcctgac
    15961 gcggcgaagc acgcaatact tctgcgccaa aacgcgccac gtcatgcacc gcggtaaacg
    16021 aagtcaccat ctcaacgtaa cagcaggaaa gaccgaagtt atacggccaa attgagtttt
    16081 tacgacccca gttaaccatg tcattgagct tgcccataaa cacgtttttg ttaacttctt
    16141 gctccagagg gtcggttacg atctcctgct tttgcagggg gtaacggtcg ttctcaccgt
    16201 tgggatctat gcgggtgagc gtataatcca tcttaatgcc tcgcggttag cgttgacgat
    16261 tagcgatact gttcgtttcc gggttcatac gctcgcggcg tgaacgcgcg ggcgtccagt
    16321 ccagcgcgcc aatacgcacc agataaacca gacctgccag taacacaaaa ataaaaattg
    16381 cagcttccac aaagcctacc cagccgcttt cgcggataga ggttgaccat gcgaacagat
    16441 acagcgcttc aacgtcgaag ataacgaaga acatggccac cagataaaac ttggcggaca
    16501 ggcgtaagcg ggcggagccg accgagtcga taccggattc aaacggcacg tttttcgacc
    16561 tcgcgcgtgc gcgaccgcct aaaaaccaac cgcctaccag catcaggcaa cacaggccaa
    16621 tggcaacgat aagaaagata gcgaatgccc agtgatgagc gatgacttca gtggatgttg
    16681 acatactcat tgcttactca tcaaaagtag cgccagattc actgctcttc acggcagatg
    16741 gacgccacat cgattcatgg ggaggaataa aaaaaaacct tacaatcact gtagaaattc
    16801 ttttatacag ctaattgatg tggtctttta ctcctttcta taaccttttg tcaactttaa
    16861 caaaagtttc ttcacattag tttacataat atcaacacca ttagcattta atgccctttc
    16921 accccagatc cttgacgact ccaggataat tagatgttgt tgaatcgtgt ccgttgtgaa
    16981 gcaatggaaa aaatacgggc ctattttgac aggaatttgt gtcgattcct ccccccaaaa
    17041 gagagtattt tcttgatctg tgacacgctt ttgtcattcc ataacaaaaa cgcatcaaca
    17101 aatttacgta ttttttaaca tcattgtagc aggtgatttt tttcaggcga ttatttgtgc
    17161 gttcgggact tgaatctctg gtgattgaaa aatgaacagt tttgtacgtt ctgcacgata
    17221 cgaggaaggc tttttactaa aaaaaagccg ctggggttta aaacaccccc agcggctcgt
    17281 ttttacacta ttgtctcaga aattatctat ggtccgtcga ttactcgata tccctttcaa
    17341 tcaacaatga gtcatcgcct tccggagcag acattgggct gtattgccac ggattatggt
    17401 agctctccat cgcctgatag atcacctgag ccagctcatt attactggac gggtcatagc
    17461 acagcaaata ttcggtatcg ggtagcggcg gtaagccatc tactccactc agcacacgca
    17521 ggtctggact catcatctcg accggccttg ccgtcacgcc aagaccggct tttactgccg
    17581 cacgaactgc cggaagcgtc gaggcgacat aagccagtcg ccatggaata tctgctttat
    17641 taagcgtcgc cagcaccata tcgcgaaacg ggctaggatc atccagcagt acaagaggga
    17701 tcggctcgcc tttttgcaat acgtattccg ctgcgcagta ccagtgtgtt ggcgaggtac
    17761 gcaggttcaa tgccttaaac gttgaaggac gatgggtggt taccatcaaa tccacttcct
    17821 gggattccag catttctgcc atataggcat tacgtttaac gcggacatcc agcgctagtt
    17881 tcggataaac cgaactcacg cgatttaaca ggaaaggtaa gatcgtatcg gcagattcat
    17941 ctgaagcacc gatagttaac acgccctgaa gattactgaa cattaatgat gagcaggcct
    18001 catcattaaa acgcagaatt tttctggcgt aaccaagaag ttgaatgcca tgttcagtta
    18061 acagtttgtt gcgaccgtga cgagcgaaca gttctttccc aacaagttgt tccagacgct
    18121 gcatttgctg acttacggcg gactgagtac gacacacagc ggcagctgcg gcagcaaaag
    18181 tgttcagatc ggcaacagca acaaatgttc tcagcagatc gaggtcgagg ttaattatcg
    18241 gacgatttgc acttatcata tattatcact tactggcggc tcatactgag ctggttaatg
    18301 ctgtgcacac acaaacaagc aattccattt gtaatgtgcc tccctggcag tttcatccgg
    18361 aacccggacg aaagtaaaaa tgcatatgag ttgcactaaa aaagcgactc acattgttcc
    18421 gttataatgc ctgaagtaga tcacagaata tatcttcagg aatcgcatat ctattaagtt
    18481 actcactctt ttgtatttat gacatgcgcg tgtttgtata aatgtaaatg tgagtccttg
    18541 ttccactctc gtgcagcatc gctggtcata cgcgaacacg tacaaacagc aatggtgagg
    18601 cggcatcaag agcagggatc cgtcatttat gcgagcattt taccccaaaa accttttatt
    18661 tataagggtc attgcgaatt atctgatgca aagttatgtt atgttaggca aagtaatctt
    18721 ctattattaa taagcacaac aaaacctttt tgaatattaa ataataatta attagcatca
    18781 tcctcataca ttaatcccgc ttaacaatag tttcacacct tgcacccatt acgacacctc
    18841 ggaaatcatc acgctgttaa actctccgta atgcggaaat atcatcatca cgattcatta
    18901 gtgaattctt aaacgaggca ttttcaaaca attatcttac agataaaaaa accacactca
    18961 caattaagat tcagaacaat tcactacata acattaatta ctaagcatat acacctcatt
    19021 attttgccat tattaagtta ttaacagcac aatcgagtct tcccctctgg caaaatctta
    19081 ttctgcagac cttcaaaacg ccgtcctggg ggagtacatt gttctaagct gacttccacg
    19141 gcagggagtg gcgataacag caaaaaaggt caagattcat gtcccccatt gaaaaatcca
    19201 gcaaattaga gaatgtctgt tacgacatcc gtggtccggt gctgaaagaa gcaaaacgcc
    19261 tggaagaaga aggtaacaag gtactgaaac tgaacatcgg caaccctgcc ccgttcggtt
    19321 ttgacgcgcc agatgaaatc ctcgttgacg tgattcgcaa cctgcctacc gctcaagggt
    19381 attgcgattc caaagggctt tactccgcgc gtaaagccat catgcagcac taccaggctc
    19441 gtggcatgcg tgatgttacc gtggaagata tttacatcgg caatggtgta tcggagctta
    19501 tcgttcaggc aatgcaggca ttgctgaaca gcggcgacga aatgttggtt cctgcacctg
    19561 attacccact ttggaccgcg gcggtttcgc tctccagcgg taaagcggtg cattatcttt
    19621 gcgatgaatc ctctgactgg ttcccggacc ttgatgatat tcgcgctaaa attacgcctc
    19681 gtacgcgtgg gatcgttatt atcaacccaa ataacccaac tggcgcggta tattccaaag
    19741 agcttttaat ggagatagtg gagattgcac gtcagcataa tctcattatc ttcgccgatg
    19801 aaatttatga caaaattctc tacgacgacg ctgagcatca ctcaattgcg ccgctggcac
    19861 ctgatctgct gactattacc tttaacggac tgtcgaaaac gtaccgcgtt gctggcttcc
    19921 gtcaggggtg gatggtgttg aacgggccga aaaaacacgc caaaggttac atcgaaggtc
    19981 tggaaatgct ggcctcaatg cgcctgtgtg ctaacgttcc tgcgcaacac gccattcaga
    20041 ctgcactagg cggttatcag agcatcagtg aatttattac tcccggcggg cgtctttatg
    20101 agcagcgtaa ccgcgcgtgg gaattgatca acgatattcc gggcgtttcc tgcgtgaaac
    20161 cgcgcggtgc gctgtacatg ttcccgaaaa tcgacgccaa acgctttaat attcacgacg
    20221 atcagaaaat ggtgctggat ttcctgttgc aggaaaaagt tctgttggtg caagggacgg
    20281 cattcaactg gccgtggccg gatcacttcc gcattgtcac gctaccgcgt gtcgatgata
    20341 tcgagctgtc tttgagcaag ttcgcgcgtt tcctttctag ttatcatcag ctgtaatctt
    20401 aatttcactg ccggagattg catccggcag tgttatcccg ccacaatgac ctgatgatgt
    20461 catcatacgt aaggtcacta tgaaacagag ccattttttt gcccatctct cccgcctgaa
    20521 actcattaac cgctggccgc tgatgcgtaa cgtgcggact gaaaatgtgt ccgaacacag
    20581 tttgcaggta gcgatggtcg cccatgcgct ggcagctatc aaaaatcgga aatttggcgg
    20641 taatgtcaac gccgaacgta tcgctttact ggcgatgtac cacgatgcct cagaagtgct
    20701 caccggcgat ctccctactc cggtgaaata cttcaattcg caaatcgctc aggagtacaa
    20761 ggcgattgaa aaaatcgctc agcaaaaact ggtcgatatg gttccggaag agctgcggga
    20821 tatctttgcg ccgttaattg acgagcatgc atatagcgat gaagaaaaat cgctggtgaa
    20881 acaggcagat gcactgtgtg catatctgaa atgtctggaa gaactcgcgg cgggaaataa
    20941 tgaattcttg ctggcaaaaa cgcgactgga agcgacgctt gaagcgcgcc gcagccagga
    21001 gatggactac ttcatggaag tctttgttcc cagcttccat ctttcgctcg atgagattag
    21061 ccaggattca ccgctgtaag cggccggagt ctgcgtcgca tcaggcaata agcgccggat
    21121 gcgacatcag gctcttgtca aaacggaaac agcatcggga tcatcaccac acaaaccgcc
    21181 atcacgataa tggtgaacgg tacccccaac ttcacaaagt cactgaagct gtaatttccc
    21241 ggacctaaaa ccagtgtgtt aacaggtgaa gaaaccggcg tcataaaggc ggcggatgct
    21301 gccatcgcca cgaccatcgc aaatggataa ggcgacacac ccatcgtttt ggcagcagcc
    21361 agcgcaatcg gagccatcaa caccgccgtt gcggtattag agataaatag cccaataacc
    21421 gccgacaaga caaacaaaca acccagcatc atatgtggcc cataaccgcc gccaatgtcc
    21481 atcagccctt tcaccgccag cgcgacacct cccgttttct gtaatgccac agcaaatggc
    21541 atcatcccaa cgatcaaaat aatgctcggc cagtgaatgg atttataggc gctttcagca
    21601 tcgatacagc ggaatttccc catcagcagg caggcgatga tagcggcaac aggattaggg
    21661 atttcatcgg tcagcattaa cgccaccatc aacaccaggc aaaaaatggc atgaggtgcc
    21721 tgactgtgtg ctggcgatgc ttcactcact tcttctggta agttcagcgc cacaaagtca
    21781 cgcccctgtt ttgccagcat accgatcagt ttccagttac ccacaaccag gatgatatcg
    21841 cccagcagca gaggctcatc cgccagcgaa ccttccatcg cctcgccatt gcgctttagc
    21901 cccaccacat tcagtccgta gcgggtacga aaaccaattt cgcgcaccga tttaccaata
    21961 agttcagact caggaattaa tgaaatctct gccatgccca catcaagtgc ctggtcagaa
    22021 aaatactcgc cgcgtagtac catcggctcc agcaactgct cactacaaaa ttgccggaga
    22081 tcgacatcag ccgcagacat atcaataagc aaaacgtcac gcgcgcgaaa ttcagaaacc
    22141 ccattaacgt tcacgataac gcgacgaaaa cgccgccagc gttcaacacc gatgacgtta
    22201 gcgccataac gctcacgtaa tttgagatcg tccagccgtt gaccaatcat tggcgatccg
    22261 gggcgaatag ccagacgtcg cgcacgcccg gtcagtcgat attcacggat aagatcgcga
    22321 aaggttcgac gcgtccagcc ttcgcgctgc ggggtctggg tatccccttt cagcatgaaa
    22381 cgcatcacta acatatacaa aatacccagc accagcacga ccaggccaat aggtgttacg
    22441 ctaaagaaac tgaagccgtg atagccttca cgcagcaatt cactgttgac taccaggttc
    22501 ggcggcgtcg ccaccagcgt catcatgccg cttatcagcc cggcaaaact taacggcatc
    22561 atcagacgcg acggcgacgt ttgcatacgc atggcaacgc ttaacaccac gggaataaag
    22621 atagcgacaa cgccggttga actcataaac gcgccaagcc ccgcgacggt cagcatcaac
    22681 aaaaccaaca ttttgatttc actgttgccc gccactttga ccagccatgt ccccattaca
    22741 gtggcaacac cagtacggac caaaccatcg ccaataataa acaaggcggc aatcaggaca
    22801 acgttaggat cggaaaagcc ggaaaatact tcggggaccg tcagcgttcc gcttaatgca
    22861 aacgcgacaa taacaaacaa agcgaccgca tccatacgca ctctgcccgt cgcaaacaag
    22921 acgatggcaa cggccagtaa tgaaagaacc caaatcaatt caccgttcac aacttatcct
    22981 tgttaattga gggggatgac ttgattctgc cataaaaaag ccccgacgag acggggctaa
    23041 atcatgatca ggtgtttcac tgaataataa catcaccatt tggctgtttg gtcacagtaa
    23101 tttgctccag actgtggagg accaaatcga cctcattcag gcgcggggta tctgccggag
    23161 cgttaaccgc aatgacatga caacccgccg ccaggccaga aagcacgcca gcgggagcat
    23221 cttccaccac cacacactcc tgcggcgcaa gccccagcag ctgcgcgcct aacagatacg
    23281 catcaggttc tggttttccg cgcttcactc gctcagcggt tacaaacacc tctggtgcgg
    23341 gaagcccagc tactttatgg cgcgctcgcg ctaccggcat ggagccagaa gtcacaatgg
    23401 cccacggaat acctgcttta ttcaaatgat tgagtaaggc gattgccccc ggaagcgcgg
    23461 taataccctc ggtttccgtg gcctcgattt gctccagacg cgtaaactcg gcggcaatat
    23521 cagcctcgga tttgcccgcc ataaaatggc gcagagaggt gatcgcctgt ttaccgtgaa
    23581 tgaaagccag cacctcttcc ggcgctaacc catgacgtct ggcccagttg ctccacgccc
    23641 gctctaccgc aggcagggaa tccaccagcg ttccatcaag atcaaacaga aaacctttgc
    23701 accgcacgcg gacctcctca ggcgttgata atttgattaa tttcgttggc gctcaaatgg
    23761 tactgacgcg ggcaggcatg ccacacatta agcatgcgct gatatttttc ccacattggc
    23821 gtctgggcgt taaaaccgtg agttccggcg tcaaaatggg tatagcgccc ttccacatta
    23881 accataaagc ggacataacc gaggtaacgt gcttcagtgg cggcgtcaaa gccgaggaag
    23941 gtaacacgac gttcatcgat ggattgctgg tcctgcaaat tagaccagga aacatgcaac
    24001 gcatgataca tctccataat gtcgatgata gtgcggcagg tttcttcttt cagctcgcca
    24061 aactcgcgat ccagttcacg catctgtaat ccataaccac gctcaatgat tgttttcagg
    24121 cgacggtaac gttcagcatt tgccggatcg agcatagtca tcatcttgta ctggttagac
    24181 aaaataagac gttgcgcgtt ggtcatttcc attgttgact cctgtatcac tctactacgg
    24241 tgaaaaaaaa gaaggctgag tatgccttct tttatatgcg taatcagggg tcaattacaa
    24301 atcatcaagg aaagttttat ccagttgttt gaaggcgcgc ttaagcgtgt cagctaatgc
    24361 ctggtaatca ggcttgcctt caacgggtgc caacacctgt ccagactcct gcaatttacc
    24421 gcgaacttca taaaaccagt tgaggatagc agggggtaat ggcgttacag aacgcttgcc
    24481 cagccaccac aatccctgca tgggtaaact taaggcgaac agcgcagtgg caactgccgg
    24541 cccaagctga ccgcccaggg caatctgcca gcagagagta aatacggcga tcggcggcat
    24601 aaaacggatc gcataacgcg tcatcttgat aacgcgattt tcgacaaaga ccggggcaag
    24661 gcgtttttcc agcggccacg tctttgagta atgctgtccc cggcgaaaca agctaaaaaa
    24721 attaacagaa cgattatccg gcgttgacat gcttcacctc aacttcacat ataaagattc
    24781 aaaaatttgt gcaaattcac aactcagcgg gacaacgttc aaaacatttt gtcttccata
    24841 cccactatca ggtatccttt agcagcctga aggcctaagt agtacatatt cattgagtcg
    24901 tcaaattcat atacattatg ccattggctg aaaattacgc aaaatggcat agactcaaga
    24961 tatttcttcc atcatgcaaa aaaaatttgc agtgcatgat gttaatcata aatgtcggtg
    25021 tcatcatgcg ctacgctcta tggctccctg acgttttttt agccacgtat caattatagg
    25081 tacttccatg tcgagtaagt tagtactggt tctgaactgc ggtagttctt cactgaaatt
    25141 tgccatcatc gatgcagtaa atggtgaaga gtacctttct ggtttagccg aatgtttcca
    25201 cctgcccgaa gcacgtatca aatggaaaat ggacggcaat aaacaggaag cggctttagg
    25261 tgcaggcgcc gctcacagcg aagcgctcaa ctttatcgtt aatactattc tggcacaaaa
    25321 accagaactg tctgcgcagc tgactgctat cggtcaccgt atcgtacacg gcggcgaaaa
    25381 gtataccagc tccgtagtga tcgatgagtc tgttattcag ggtatcaaag atgcagcttc
    25441 ttttgcaccg ctgcacaacc cggctcacct gatcggtatc gaagaagctc tgaaatcttt
    25501 cccacagctg aaagacaaaa acgttgctgt atttgacacc gcgttccacc agactatgcc
    25561 ggaagagtct tacctctacg ccctgccgta caacctgtac aaagagcacg gcatccgtcg
    25621 ttacggcgcg cacggcacca gccacttcta tgtaacccag gaagcggcaa aaatgctgaa
    25681 caaaccggta gaagaactga acatcatcac ctgccacctg ggcaacggtg gttccgtttc
    25741 tgctatccgc aacggtaaat gcgttgacac ctctatgggc ctgaccccgc tggaaggtct
    25801 ggtcatgggt acccgttctg gtgatatcga tccggcgatc atcttccacc tgcacgacac
    25861 cctgggcatg agcgttgacg caatcaacaa actgctgacc aaagagtctg gcctgctggg
    25921 tctgaccgaa gtgaccagcg actgccgcta tgttgaagac aactacgcga cgaaagaaga
    25981 cgcgaagcgc gcaatggacg tttactgcca ccgcctggcg aaatacatcg gtgcctacac
    26041 tgcgctgatg gatggtcgtc tggacgctgt tgtattcacc ggtggtatcg gtgaaaatgc
    26101 cgcgatggtt cgtgagctgt ctctgggcaa actgggcgtg ctgggctttg aagttgatca
    26161 tgaacgcaac ctggctgcac gtttcggcaa atctggtttc atcaacaaag aaggtacccg
    26221 tcctgcggtg gttatcccaa ccaacgaaga actggttatc gcgcaagacg cgagccgcct
    26281 gactgcctga tttcacaccg ccagctaagc tggcggtgct gttttgtaac ccgccaaatc
    26341 ggcggtaacg aaagaggata aaccgtgtcc cgtattatta tgctgatccc taccggaacc
    26401 agcgtcggtc tgaccagcgt cagccttggc gtgatccgtg caatggaacg caaaggcgtt
    26461 cgtctgagcg ttttcaaacc tatcgctcag ccgcgtaccg gtggcgatgc gcccgatcag
    26521 actaccacta tcgtgcgtgc gaactcttcc accacgacgg ccgctgaacc gctgaaaatg
    26581 agctacgttg aaggtctgct ttccagcaat cagaaagatg tgctgatgga agagatcgtc
    26641 gcaaactacc acgctaacac caaagacgct gaagtcgttc tggttgaagg tctggtcccg
    26701 acacgtaagc accagtttgc ccagtctctg aactacgaaa tcgctaaaac gctgaatgcg
    26761 gaaatcgtct tcgttatgtc tcagggcact gacaccccgg aacagctgaa agagcgtatc
    26821 gaactgaccc gcaacagctt cggcggtgcc aaaaacacca acatcaccgg cgttatcgtt
    26881 aacaaactga acgcaccggt tgatgaacag ggtcgtactc gcccggatct gtccgagatt
    26941 ttcgacgact cttccaaagc taaagtaaac aatgttgatc cggcgaagct gcaagaatcc
    27001 agcccgctgc cggttctcgg cgctgtgccg tggagctttg acctgatcgc gactcgtgcg
    27061 atcgatatgg ctcgccacct gaatgcgacc atcatcaacg aaggcgacat caatactcgc
    27121 cgcgttaaat ccgtcacttt ctgcgcacgc agcattccac acatgctgga gcacttccgt
    27181 gccggttctc tgctggtgac ttccgcagac cgtcctgacg tgctggttgc cgcgtgcctg
    27241 gctgccatga acggcgtaga aatcggtgcc ctgctgctga ctggcggcta cgaaatggac
    27301 gcgcgcattt ctaaactgtg cgaacgtgct ttcgctaccg gcctgccggt atttatggtg
    27361 aacaccaaca cctggcagac ttctctgagc ctgcagagct tcaacctgga agttccggtt
    27421 gacgatcacg agcgtatcga gaaagttcag gaatacgttg ctaactacat caacgctgac
    27481 tggatcgatt ctctgactgc cacttctgag cgcagccgtc gtctgtctcc gccagcgttc
    27541 cgttatcagc tgactgaact tgcgcgcaaa gcgggcaaac gtatcgttct gccggaaggt
    27601 gacgaaccgc gtaccgttaa ggcagccgct atctgtgctg aacgtggtat cgcaacttgc
    27661 gtactgctgg gtaatccggc agagatcaac cgtgttgcag cgtctcaggg tgtagaactg
    27721 ggtgcaggca ttgaaatcgt tgatccagaa gtggttcgcg aaagctatgt tggtcgtctg
    27781 gtcgaactgc gtaagaacaa aggcatgacc gaaaccgttg cccgcgaaca gctggaagat
    27841 aacgtagttc tcggtacgct gatgctggaa caggatgaag ttgatggtct ggtttccggt
    27901 gctgttcaca ctaccgcaaa caccatccgt ccgccgctgc agctgatcaa aactgcaccg
    27961 ggcagctccc tggtatcttc cgtgttcttc atgctgctgc cggaacaggt ttacgtttac
    28021 ggtgactgtg cgatcaaccc ggatccgact gcagaacagc tggcagaaat cgcgattcag
    28081 tccgctgatt ccgctgcggc cttcggtatc gaaccgcgcg ttgctatgct ctcctactcc
    28141 accgggactt ctggtgctgg tagcgacgta gaaaaagttc gcgaagcaac tcgtctggcg
    28201 caggaaaaac gtcctgacct gatgatcgac ggtccgctgc agtacgacgc tgcggtaatg
    28261 gctgacgttg cgaaatccaa agcgccgaac tctccggttg caggtcgcgc taccgtgttc
    28321 atcttcccgg atctgaacac cggtaacacc acctacaaag cagtacagcg ttctgccgat
    28381 ctgatctcca tcgggccgat gctgcagggt atgcgcaagc cggttaacga cctgtcccgt
    28441 ggcgcactgg ttgacgatat cgtctacacc atcgcgctga ctgcgattca gtctgcacag
    28501 cagcagtaat ctcgtcatca tccgcagctt tgcgctgcgg atatctgaac cggaaatagt
    28561 cactatttcc ggttttttat tctcttaatt tgcattaatc ctttctgatt atcttgctta
    28621 gctgcgctgc atcaatgaat tgcgccatct cactttgcat acttaccact ttgttttgtg
    28681 caagggaata tttgcgctat gtccgcaatc actgaatcta aaccaacaag aagatgggca
    28741 atgcccgata cgttggtgat tatctttttt gttgctattt taaccagcct tgccacctgg
    28801 gtagttccgg tggggatgtt tgacagtcag gaagtgcagt atcaggttga tggtcaaaca
    28861 aaaactcgca aagtcgtaga tccacactct tttcgcattc tgactaacga agcaggcgaa
    28921 cctgagtatc accgcgtaca gctgttcacg acgggcgatg aacgcccggg tctgatgaac
    28981 ttcccgtttg aagggttaac ctcaggatcg aaatacggga cagccgttgg catcatcatg
    29041 tttatgctgg tgattggcgg cgcgtttggc attgtgatgc gtacaggaac cattgataac
    29101 ggtatcctgg cgcttattcg ccatacccgc ggaaatgaaa ttctctttat tcctgcgctc
    29161 tttattctgt tttcacttgg cggcgcggta tttggtatgg gagaagaggc cgtcgccttt
    29221 gccattatca tcgcaccgct aatggtccgg ctaggctatg acagtattac caccgtcctg
    29281 gtgacctata tcgccacgca aatcggtttt gccagttcgt ggatgaaccc gttttgtgtg
    29341 gttgttgctc aggggattgc cggcgttccg gtgctttctg gctccgggtt gcgcatcgtg
    29401 gtgtgggtta tcgccactct gattggcctg atctttacca tggtgtacgc ctcacgagtg
    29461 aaaaagaatc ctcttctgtc acgcgtgcat gagtccgacc gcttctttcg tgaaaagcag
    29521 gcggatgttg aacaacgtcc gtttaccttt ggtgactggc tggtattgat tgtcctgacc
    29581 gccgtaatgg tctgggtgat ttggggcgtg atcgttaatg cctggtttat tccagaaatt
    29641 gccagccagt tcttcaccat gggtctggtg attggcatca tcggcgttgt tttccgcctt
    29701 aacggcatga cggttaatac catggcttca tccttcaccg aaggggcgcg aatgatgatc
    29761 gcccctgccc tgctggtagg tttcgccaaa gggattttgc tgctggtcgg taatggtgaa
    29821 gcgggtgatg ccagcgtgtt aaataccatc ctcaacagca ttgccaatgc cattagcggt
    29881 ctggataacg cggtcgcggc ctggtttatg ttgctcttcc aggcggtatt taatttcttc
    29941 gtgacgtccg gttctggtca ggcggcgtta accatgccgt tactggcacc gcttggcgat
    30001 ctggtcggtg ttaaccgtca ggttaccgtg ctggcgttcc agtttggtga tggcttcagc
    30061 cacatcattt acccgacctc agcttcgtta atggcaacgc taggtgtttg ccgggtggac
    30121 ttccgtaact ggctgaaggt gggcgcgaca ctgcttggac tgctgtttat tatgtccagc
    30181 gtcgtggtga tcggcgctca gttgatgggc taccactaaa aatgttaaga gccgcaattg
    30241 cggctctttt ttcattctgc cgtttcagtc tctacggctt catttttggc attgcgcttc
    30301 atccacaacg ccagcgcttt cagcgagtct ggagtgaact catcgcagcg tgcggtgatt
    30361 tcttccggtg tcagccagca aacttcactg acttcatctt cctgtagggc gaagggaccg
    30421 tgagagacgc aactgaacaa cgcgccccag acacggcaat ttttatcttc gaaatagaac
    30481 tgcccgtgct cggcaaaggg gacaccggca atgcccaact cttcttccgc ttcgcgacgc
    30541 gcggattcca gcagttgctc atcggcctgg actacaccgc ctgcggtcgc atctaacatg
    30601 ccgggtaaaa agtcttttgt ctcggtacga cgctggacca gaattttgcc catgccatca
    30661 tgcacgacga tgtaagttgc acgatgacgc agacactgtg cccgcatttg ttcccggctg
    30721 gcttgtgcaa tgacttcgtt ctcttcattg acaatatcca cccattcagt acttgccaaa
    30781 cgacgctgtt ccattatcag gaaaccttct ttttctggcg ctcttacggc gcattttgag
    30841 ttgtgggtaa attacggatt aatcgcgacc tgcgcaatga tactttgatc attgagtgcg
    30901 attacactaa gtacgtcatt atccagcatg ccataactcg ccggattacc gcctttcgga
    30961 atactcaccg agccggggtt aaagtggaaa atctcccccc gctgttctgc cactggcaga
    31021 tgggtatgac cgtacaccag cacatcgttc tggtttaaag caggcagatt ttccggccca
    31081 aacagatgac catgcgtcaa aaacagacgt tgtttttcca gtaatacctg ttgccacggc
    31141 gcggttatcg ggaaatgcaa aagcatttga tccacttcgc tgtcgcagtt gccgcgcaca
    31201 gcgataacct tatgtgccac ttcattaagc cgttcagcga ctttggctgg cgcgtaaccc
    31261 tccggtaaag cattacgcgg gccgtgattc aacacgtcgc caaggatcac cagccactgg
    31321 gcaccgcttt gggcaaacaa ctccagaaca cgttccgtcg ccggtaacga cccatgaatg
    31381 tccgatgcaa acatcagttt catcactcac tcctcgtcga aaaaacgtaa gctatgatac
    31441 tggattctgt cgttgctatc agccagattg cttcgccgaa agagcaataa aacgctggac
    31501 agacgctcgc tgccactgga atgtcgcata atccaccagg cgttctggca cctcatcgcc
    31561 atgtagtacc aggcggttaa tcattagcgc cagatcagta tcagcaatgc accattcacc
    31621 aaataaattc ggccgcccca gtgctaacaa atgttctgcc atcgcgaaca gtttctctgc
    31681 actggctttt ccctccgccg ttaatggcgc ttttttcgca cccgcaaaga caacatccgt
    31741 tggacgttct tcgcggatgg gcatcagatc gctacgcagc caggcctgaa tctgtcgtgc
    31801 acgcgcacga ttttctaaat caagcggata aatgcgttcc caggtcggtg gcgcaaatcg
    31861 atcttccaga tactccgcaa tggcagaaga ttcactcaac tcaaaatcat cgatttgtaa
    31921 taacggcaca cggcgtgtct gaccgtaacc ttgccacgtc ggctgcaaat gctcaccgct
    31981 gtcgaggtcg atggtcttga tatgaaacga caggcctttt tcctgcaacg ccacccaggc
    32041 ggataacaca taaggggaga aaaaatgggc atctgaccaa agcgtgatag cgggtttact
    32101 cattatgtcc tcggcaataa aggggggggg ctagctatca aactatagag cctttttgtc
    32161 actgtcacgt gacgaatact cacgcaagtc gccgcgcttt ctatacttgt ggtgttcaga
    32221 tgattagaca accggagctg caatgatcga tctctatttc gccccgacac caaatggtca
    32281 caaaattacg ctgtttctcg aagaagcaga gctggattat cgcttgataa aggtagacct
    32341 ggggaaaggc ggtcagtttc gcccggaatt tttgcgcatt tcgcctaaca acaaaattcc
    32401 ggcaattgtt gatcattctc cagccgatgg cggcgaaccg ctaagcctct ttgagtctgg
    32461 tgccattttg ttgtatctgg ctgagaaaac aggactcttt ttgagtcatg aaacgcgtga
    32521 gcgcgccgcc acattacagt ggttattctg gcaggtaggc ggactggggc cgatgcttgg
    32581 gcaaaatcat cattttaatc acgcagcccc ccaaaccatt ccttacgcta ttgaacgtta
    32641 tcaggttgaa actcagcgtc tgtaccatgt actgaacaag cggctggaaa actcgccctg
    32701 gctgggtggc gagaactaca gcattgcgga tattgcctgc tggccgtggg ttaatgcctg
    32761 gagtcgccag cgaattgacc tcgcaatgta tccggcagtc aagaactggc atgagcggat
    32821 ccgttcgcgc cctgccaccg ggcaggcact gctaaaagca caactcggtg atgagcgttc
    32881 ggatagttaa cagaaacagg ttctcgtgta ttatttcatt ctaagtaaaa caacggagaa
    32941 cctgcaatgg cacaacctgc cgctattatt cgtataaaga accttcgttt acgtacgttt
    33001 atcggaatta aggaagaaga aattaacaac cgtcaggata ttgttatcaa tgtgacgatc
    33061 cactaccccg ccgataaagc gcgcaccagc gaagatatca acgatgcgct gaattatcgc
    33121 accgtaacga aaaacattat tcagcatgta gagaataacc gtttctcttt gctggaaaaa
    33181 ttaactcagg atgtgctcga tatcgcacgt gaacatcact gggtgacgta tgctgaagtg
    33241 gagatcgata aactgcacgc gctgcgctac gccgattcgg tatccatgac cttaagctgg
    33301 cagcgttaac cgccatatcg ggaggctgca tgaagatagt gatcaccgga gggacgggat
    33361 taattggtcg ccatttgatt ccgcgtttgc tggatctggg ccatcaaatc acggtagtga
    33421 cgcgtaaccc gcagaaagcc agttccgttc tcggccctcg ggtgacacta tggcaagggc
    33481 ttgccgatca tagtaacctc aacggcgttg atgcggtaat caacctggcc ggagagccga
    33541 ttgctgataa acgctggact cacgagcaaa aagagcgtct ctgccaaagc cgctggaata
    33601 tcacgcaaaa actggtcgat ttgattaatg ccagcgacac gccaccgtcg gtactcattt
    33661 ccggctcggc aacaggctat tatggcgact taggtgaagt ggtggttacc gaagaggaac
    33721 cgccgcataa cgaatttacc cataaactct gcgcccgctg ggaagagatt gcctgtcggg
    33781 cgcaaagtga caaaacgcga gtgtgcctgc tgcgtaccgg cgtagtgctg gcaccagacg
    33841 gtggtattct cggtaaaatg ctgccgccgt ttcgtcttgg tctgggcggg ccgattggct
    33901 ccggtcggca gtatctggcc tggattcata ttgatgatat ggtcaacggc attctctggc
    33961 tgctggataa cgagctgcgc gggccattta atatggtttc gccctacccg gtacgcaatg
    34021 aacaatttgc ccatgcgctc ggtcatgcgc tgcatcgccc ggccattttg cgcgtccccg
    34081 cgaccgccat tcgactgtta atgggcgaat cttcagtact ggtattaggt ggacaacgcg
    34141 cgctgcctaa acggctggaa gaagcgggtt ttgcgtttcg ctggtacgat ttagaagagg
    34201 cgctggcgga tgttgttcgc tgatgtggtt tactgcaaac atccgccagt taactcccgg
    34261 tgttacaggg ttagtggctt tgcgcgataa gatcgtctgg tgaaagtcgg gtcaccatca
    34321 gaactaactc tcggtctaaa cctctatcca gcatctcctg agcaatacgc agggcttctt
    34381 cgcgtttgcc aagaattaat ccatcattcc gcccttcttc acgtaatctg tcagcaatag
    34441 tcatcagttt ctccttttct tgtggtgcgc gttccgctat ctcaccaata aatgcacgga
    34501 aacgctgggc atcccccgtt tgtaatacgt aattaaacag ggcttttagc tgtctgtcat
    34561 tagtgttccc tgtaactagc agcgaaacaa tttggtcgac taatcccaac agatcgcgct
    34621 gacgaatatg tttctgaatt aactccaaca gcgccatttt gcgatgttgc ataatctcgt
    34681 catccggcac cacggtaata tccaccagcg gaaaagccga tgaataaatt tggcgggcaa
    34741 tcgcaggctc ggcaaattca tcaagccagc agagtgaata tggataagga cttctgcaac
    34801 catgataaaa cagcatcggg atcactaatg gaagctcttt atagcccgca tcaagatggt
    34861 tttgcatcgc cgcaatggaa tagcgcatca tgcgaaaagc cattaattcc tctggcttac
    34921 tttggtgctc tatcaccaca taaatataac ccgctccctc ctgcgttttc acagaccaca
    34981 agaggtcgga ataatattgc cgcaggtctt catcaataaa actgtttggt tccagtttaa
    35041 gtgttgttaa atcacacagt ttgcgcagcg gcgcgggaag atgaatatca ataaaatccc
    35101 gcgcggtgtc tggatggcgt aaaaaagatt taaataccgc atcatgcggc gtggaagttg
    35161 tcgatattgt catggcgttc cgtcacccct caaatttaag atgacgcgac aataaccacg
    35221 atttacaccc aatgcagcag gcagttttta tctttggaca gcgaattcag aactattttt
    35281 agcggactgc aacttttaca tttcagcgga agcggactcg caaattcccc ttgaaaatac
    35341 tccggtagcg ttagccaccg gagggggaat tatttcagcg atcccttaag gaactgttgc
    35401 agacgagggc tttgcgggtt accaaataac tgttctggcg cgccctcttc ttctattttc
    35461 ccctgatgga ggaaaatgac gtgagtagaa acatggcgag caaagcccat ttcgtgagtc
    35521 actaccacca tggttttccc ctcttctgcc aattgctgca taatacgtaa cacttcgcct
    35581 accagttcag gatcgagcgc cgaggtaggt tcatcaaaca gtaaaacttc cggttccatc
    35641 gccagcgccc gcgcgataga aacacgctgt tgctgaccac cggacaggtg caccgggtat
    35701 ttcccctgcg cacgttcgtc tatcccgact ttcgccagat acttcaccgc ccgctcgcgc
    35761 gcttcctgct tgctcaggcc caacacctga atcggcgctt ccatgacgtt ttccagcacc
    35821 gtcatatggc tccagagatt gaagtgctgg aataccatcg tcaggcgtgt gcgcagtaag
    35881 cgcagctgat ttttatcggc gactttgagt tgaccgtctt tgtcgcgcac cagattgatc
    35941 gtctggccgt taaccacgat cgatccttcg ctcggttttt cgaggaagtt aatgcagcgc
    36001 agaaaggtac ttttccccga tcccgacgat ccgatgatgc ttatgacatc tccggcattc
    36061 gcttgcagtg agaccccttt cagcacttcg tgttcgccgt agcgtttgtg caaatcgata
    36121 acgtttaatt tattctcgga catcgtattc tcagtgcgtt gaagaaggtt tcacatgctg
    36181 caaccagcgt ttttccgctc tgcgaaagag gctgatcagg acataagaga tgattaaata
    36241 gagcaccgcg gcaatgccga aggcggtaaa aggttgatac gtggcggcgt taatatcgcg
    36301 ggctattttc agcagatccg gcacagtagc ggtgaaagcc agcgcagtag agtgcagcat
    36361 caggatcact tcgttgctgt aggccggtaa cgcaatacgc agcgccgatg gcaaaataat
    36421 gcagcgatac attttaaagg tcgagaagcc ataggctctg gcggcttcga tttccccatg
    36481 cggcactgaa cggatcgctc cggcaaaaat ctcggtggtg taagcacagg tgttaagcgt
    36541 cagcgccagc acggtacagt tcaggccact gcgaaaaaag gcgttaagaa actcggtccc
    36601 cttaacaatc tccagcgtat acatgccgga atagaacacc agcaactgaa catacagcgg
    36661 cgtaccgcga aaaatatagg taaataacca gattggaaac tggatgtatt tattactgga
    36721 gacacgacca atcgccagaa acagcgccag aactccgcct atcactaccg acaaaatcag
    36781 cagccacagg gtgatcgcca cgccagtaaa gcgataaccg tcggtccaca acaacggttt
    36841 ccagtattca tgtaagattt cgatcacagg tcagccctct tcacacccac ggagtagcgg
    36901 cgctcaagga ccagcagcac accattggaa acagtggtga aaaccaggta aatcacgcca
    36961 cagacgatgg cgaaatagaa cggttcccag gtacttttgc ctgccagctg cgtggctttg
    37021 accacatctt ccaggccaag taacgaaacc agagcggtag atttgaggat cacctgccag
    37081 ttgttgccaa tgcctggcag ggcgtaacgc atcatcgccg gaaacatgat ccgccgaaac
    37141 acttgcccac gagtgaaacc gaacgccgtc gccgcctcta tatgtccttt cggcactgcc
    37201 ataaaagcgc cacggaacgt ttcggtaaaa taagcaccgt agataaaacc gagagtaata
    37261 ataccagcga ccatcggatc gatatcaatc tgcccgacgc ccatcgcctc cgtcaccgtg
    37321 tttagtgcaa tctgcaaacc gtagaaaatt agcagcatca acaccaagtc cggcacgcct
    37381 cgaatcagcg tggtgtaccc ttcgaaaatc agccccgaaa gccgattttg cgagagctta
    37441 ccgccagcgc caattaaacc gatgattaca gcgagcacta cagagctgat agccagctcc
    37501 agcgtgacga gcgcaccctg taaaataaca cctgaaaacc catacaacat gctgcctgtc
    37561 ctgtcgtgtg tggtgaatta ccgcctcttg tctccctccg gttacccgaa gggagcggac
    37621 tttctttcac cgatggcgat taaccaccat aaacatcaaa atcgaagtac tttttcgcta
    37681 atttctcgta agtaccgtca gcgcgcattt cggcaaaggc tttgttcagt gcctcgcgca
    37741 gttcgttatc ttctttacgc aggcccatgc cggtccctac gccaaacagt ttttcatctt
    37801 taacagacgg accaccgaat ttgtaatctt taccgacggg ttgtttgagg aaaccttcgc
    37861 tggctgcgac ctcatcctgg aacgcggcat caatacgtcc ggcagtcagg tcagaataaa
    37921 tattgtcctg cccctgataa gaaacgattt caatgccttt tggtgcccag tgttcgttac
    37981 cgaacgtctc ctgggtggtg ccctgcaata cgcctacccg tttgcctttc agcgattcga
    38041 ctgtcggctg aatgtcggaa tttttcgcca ccaccagacg agaatcggct gcgtatagtt
    38101 tgtcggtgaa tgctatttct tgctgacgtt tttccgtaat ggaaagcgat gacatgatgg
    38161 cgtcaatctt cttcgctttt aaggacggga ttaacgcatc cagtgggttt tcgacaaacg
    38221 tacattgcgt attgatgcgt ttgcacaact cctttgccag atcgatatcg aagccaacca
    38281 gttcaccttg tgaatttttt gattcaaatg gcgcataggt cggatcggta ccgatgcgga
    38341 tgttttgcgg aatcgcagca aacgccacag ttgcgctgga gaaggccaga accagagaga
    38401 gcgatagcac cagttttttc ataatgtcct caactgacag tctttttata gggaatattt
    38461 acaggtttgt tacacttatc gtgccataaa attgaccatc aaggcaaaat atcccgcccc
    38521 gttagacgta ttatttttca ttaaaaatgc ttaagtatgc atttcaatgc accacgatag
    38581 tgcaacaaac ctgccgtgca ccatgatgat cattccatca ggtacagctt ccctgcgacg
    38641 tatcagtcac cgtagacatt aaagtcaaaa tactttttcg ccatcttgtc gtaggtgccg
    38701 tcctgacgca gctcgccaag cgccttatta aacgccgccg tcagttccgc atcatcttta
    38761 cgtagcccta caccggtgcc gtcaccgaag tattttttgt ctttcactga tgagccagca
    38821 aaggcgaagt ctttaccagc aggttgcttg aggaatcctt cgctggcagc aacttcatct
    38881 tgtaacgcag catccagacg tcctgcagcc agatcggaat agaccaaatc ctggttggca
    38941 taggccacca catccacacc tttgctacgc caggtctcgt tagcgtaagc ttcctgggtt
    39001 gatccctgca gcacaccaac atgtttacct ttcagtgaat ccagcgttgg ctgaatcggc
    39061 gaacctttgg cggcaatcaa acgagaatct gcggcgtaca gcttgtcgga gaaagcaatc
    39121 tcctgctgac gtttatcggt aatggaaagc gacgaaataa tggcgtcgat ttttttcgct
    39181 ttcagtgagg ggatcagcgc gtcaaagtca ctggcaaccc aggtacattt cacctgcatc
    39241 cgtttgcaca tctcgttacc gagatcgata tcaaagccaa caaagtcacc tttggcatct
    39301 ttcgatgaga acggcgcata ggtggtatca gttccgatac gtaccgtctc cggtagcgcc
    39361 gcatagctgg aagccgctgc ggagagaccg actaacaaag acagagcgag aatcgacttc
    39421 ttcatacata accctcaagt gaaaatggct tttttatgtt gtgtattgtg ttgtgtgttt
    39481 gcaggctctt tcatgcaggt cttatgccat ctttacgaca gcagtaacat tcaacgttaa
    39541 acatgttaat aagacgttgc attattgtcc tgaagttgaa gatagcaggt atggcggttg
    39601 aatcgcagcg tttcgattca tcgaaaggaa caaaatgtcg aggatttgat cgcggttgca
    39661 aaattgccct gaaacagggc aacagcggag ttatgcgccc tgccagcggg caaagagatc
    39721 ttcaggaagc gttatggcga attgatcgag tacacggtta accgtctgat ttatcacatc
    39781 atcaagggat tgcgggcgat gataaaacgc cggaacggga ggcataatca ccgcaccgat
    39841 ttctgctgcc tgagtcatta aacgcagatg gcctaagtgc aatggtgttt cacgtacgca
    39901 gagcaccaac gggcgacgct ctttcagcac cacatctgcc gcacgggtca gtaagccatc
    39961 agtatagcta tggacaatgc cggacagggt tttgattgaa cagggtaaaa tcaccatccc
    40021 cagtgtctgg aaagaaccgg aagaaatgct ggcagcaata tcgcgcgcat cgtgcgtcac
    40081 atcggctgat gcctgcactt cgcgcaggga aaaatccgtt tcgagggata aggtctggcg
    40141 cgcggcctgg ctcatcacca aatgcgtttc aacatctgcg acatcgcgca gaacctgtaa
    40201 taagcgcacg ccataaatcg cgccgctggc accgctgatg cctacaatga gtcgtttcat
    40261 aaatagttgc cctgtcagac ttgcaggcag actttgcagg atttcggcgg gagttgcaag
    40321 tcagggtgcc agaccggcac cctgagcgaa ggcatcatcc ttcgttatgc atttcgagat
    40381 tttccacttc gttctgacgt tgcactgctt tggcgtcatc attacgtaac gtatcgagga
    40441 aatcgaggta gccctgatca acatctttgg tgacgtagac gccgttgaac accgaacact
    40501 caaactgctg aatatccggg ttttcagcgc gaacggcttc gatcagatcg ttcagatcct
    40561 ggaaaatcaa cccgtcagca ccgatgatct ggcgaatttc atctacttcg cgaccgtgag
    40621 cgataagctc cgtagcgctc ggcatatcga taccgtaaac gttcgggaag cgaatctccg
    40681 gtgccgcaga agcgaggtac actttcttcg ctccggcttc gcgtgccatc tcgataatct
    40741 gctcagaagt ggtgccacgg acgatggagt cgtcgaccag caggacgttt ttatcgcgga
    40801 actcggcgcg gttggcgttc agcttacggc gcacggactt acgacgcagt tgctgacccg
    40861 gcatgatgaa ggtacggcct acatagcggt ttttaacgaa gccctgacgg tacggtttgc
    40921 ccagaatacg agcaatttcc agcgcgatat cacacgaggt ttccgggatc gggatcacca
    40981 cgtcgatatc cagatcttcc cattcgcggg caattttctc gcccagcttc gtgcccatat
    41041 tcacacgcgc gctgtaaacg gaaattttgt cgatgaacga gtccgggcga gcaaagtata
    41101 catactcaaa caggcacgga ttgctgaccg gattgtcagc acattgacgg gtaaacaact
    41161 gcccttcttc agtgatgtaa atcgcttcgc ccggcgcgac gtcacgcagg aaatcaaagc
    41221 ctagtgtatc gagcgcaacg ctttcggaag cgaccatata ttctgtgcgg ttctcgtcaa
    41281 tatcacgttt tcccagtacc agcggacgaa taccgttagg atcgcggaaa gcaaccatac
    41341 cgtggccgat aatcatcgcc acacaggcat acgcgccgcg gattaagcgg tttgtggcag
    41401 caatggcagc gaaaatattg tcggcttcca gcgggtagtg gcggaagttg tccagctcgc
    41461 tggcgaagat attaagcaga atctccgagt cggaagtggt attgatgtgg cggcgttttt
    41521 cttcaaacag ttttttacgc aactcgtgag cgttggtcag attgccgttg tgggcaagcg
    41581 taatgccata cggagagtta acgtaaaacg gctgcgcttc agaggcgctg gagctgccag
    41641 ccgtagggta acgcacatga ccaatgccca tattgccctg caaacgctgc atatggcgag
    41701 cttcaaatac atcgctcacc agcccgttcg ctttacgcaa acggaagcag ttattggcat
    41761 ctatggtgat gatgccggcg gcatcctgac cgcgatgctg aagcaccgtt aaggcatcat
    41821 aaatcgactg gttaaccggc ataacaccgg cgataccgac aataccgcac atacgtcttt
    41881 ttcctcgtta agccacatct cagagcactt acgctctggg caagaaactt gacgagcttt
    41941 gcagataatc aaaaaaccat ctgatgataa aactgaactg cgggatcagc tgtgatttgc
    42001 tccagtcttc gcttttcgac accccggtaa aggagtcgag aaagaagaga atggcggcaa
    42061 caatcaacac accgcgcaac gcaccgaaac agacgcccag cacccgatcg gtgcctgaca
    42121 accccgtttt ctccaccaac tggcctatca cgaagttcac gatagcacca acgatcaggg
    42181 tagcgataaa cagtaccgcg atggcaatcc catttcgaac cagttcgtct tcaaagcccg
    42241 taaaccagac tgacaggtaa gtgtagtaat gactggcaac aaagaaagca caaccccatg
    42301 tcaccagcga taacgcttca cgaacaaagc cgcggatcag gctaaccaga gaggaaaaag
    42361 caatcaccgc gattatggcg taatcaatcc agaccatatg tgtcccacga ttttacgccc
    42421 tgtcatcctg ttcggggcgc attctaacag aaaaagaaaa cgtttgcgta gggatttcct
    42481 tcccacgcat caataaaaat ggcgctgaaa aaatattcaa cgccatcgac tttttatgcc
    42541 tttgcggcat cgggcaatgc gtgtcggatg cggcgtaaac gccttatccg acctacgttt
    42601 ctactcctgc gtaggactga taagacgcgc cagcgtcgca tcagataaga ccgtattaat
    42661 tcggcgtata acccattacc acgccactta agccagaaag ttgcttcaac tcacccagcg
    42721 aacctttcag cttatctttc gaggcatctg gcccaaccag aatacgagta attttaccct
    42781 gcactggcgt ggatggcgac gtataaaccc gataaccggc accgcgcagc ttaccgacaa
    42841 tctcattcac tttatcggca tttttcagtg cgcccagttg tacaacatag gctttacccg
    42901 ttggcgctgc tttttcttcc acgaccggct tcggcgcagg tggtgcttca accttcggtt
    42961 tcggcggctc taccggtttc ggcttcggtg ggacgaccgg tgcaggttcc ggttcaaact
    43021 cggtgttatt ggctgcaata gtggccggat cgagcgacgg tgctgcggca tcacctgccc
    43081 gcacctcttc cgctgcgcct tccggcggct gcgtcggcag cgcctgggtg gcggctggca
    43141 tcatatcagg ctcatcgcga tcgcccgctt ttggcaccag cgggatagcc gcgaactcat
    43201 cctgataatg ttttttctgc ccgtccagca gccctggaag tacaatcacc cccagcgcca
    43261 ccagcacgat cgtgcccact aaccgattct gaaacttact tgccaccgct tctcctcgcg
    43321 tcaatcactt ccatgacatg tgcgaccgtg tggaacgaac cacacaccag cacggtatct
    43381 tccgctttag cgtccgccat tgcggcatcc catgcctgcg ccacgctatc aaatgatttg
    43441 ccgttaccca aatgctcaag cagttgttct gccgtggcac cgcgcggccc ttccagtggc
    43501 gcacaatacc agtcatcaac cacgcttttc aaccaggcca gagttccggc aatatcttta
    43561 tcatgtagca taccgataac cgccagcacg cgcccgtttt tcggtagcgc tttcatacgc
    43621 ccggtgagat attccgccgc atgtggatta tgcgcgacat caaaaataac gcgtggtgac
    43681 tcgctcacaa tctggaaacg tcccggcaaa attgcgttgg caatcccgtc gcgaatggca
    43741 ttttcactga cctccagccc gctggcacgc agtgccgcca gcgccgttgc ggcattcggt
    43801 tgcgggacaa gcggcaacgg cagattttcc agcgtgccgt gagcatcgct aaacgcccag
    43861 tcatgatcgg tgacggaata gttccactca acgccccgac gttgtaacag tgcacttttt
    43921 tcctgcgcca catcagcaat ggtagaaggc atttccggct caccgacaat tgccggtttt
    43981 tcgctgcgga agatgcctgc tttctcgcga ccaatgcttt cgcgatctgg ccccagccag
    44041 tcggtatgat ccagcgcaat gctggttact accgcaacat cggcatcgac aatattggtt
    44101 gcgtccagac gaccgcccag ccctacttcc agaatcacca cgtcaagttg tgcctgtttg
    44161 aacagccaca acgccgacag cgtaccgtac tcgaaatagg tcagggaaat atcaccgcgt
    44221 gccgattcaa tctccgcaaa agaggcggtg tgggccgatt ccggcaattc ctgcccctgc
    44281 acacgtacgc gctcggtata acgcaccaga tgcggtgaac tgtagacgcc cactttgtac
    44341 cctgccgcca tcagaatcga ctccagcgta cggcaggtgg tgcctttgcc attcgtaccc
    44401 gcaacggtaa acacaaatgg cgctggtttc agaacgccaa gacgcgccgc gacctggctc
    44461 acgcgctcaa ggccgagatc gatagtttta ctgtgcaggt tttccagata agaaagccac
    44521 gaagccagag gcgacgcggc ttgaggagtg cgtttgataa tcatggtatc cgctgattcg
    44581 ttacggtgag aatagcaaaa gggcagagcc agtggccctg cccttatcag ttatcaggcc
    44641 tcaggttcct gatctggtac cggtggcacc actacgcctt cacgcggcgc ttcaggattc
    44701 ggcgctggca gattcatcaa cttcgccaga atactcgcca gtttcaggcg catttccgga
    44761 cgacggacga tcatgtcgat cgcgcctttc tcgatcagga attcactgcg ctggaatcct
    44821 ggcggcagtt tttcgcgaac ggtctgttcg ataacacgcg gaccggcaaa gccgattaac
    44881 gctttcggtt cagcgatgtt gagatcgccc agcatggcga aacttgcaga aacaccgccc
    44941 atggtcgggt cggtcagcac ggagatgtac ggcaagccgc gctcctgcat ttttgccagt
    45001 gccgcagagg ttttcgccat ctgcatcagc gacatcagtg cttcctgcat acgtgcgcca
    45061 ccagaggcgg agaagcagat cagtgggcag ttatcttcca gcgcctgctc aacggcacgc
    45121 acgaaacgtg cacctaccac agaccccatg gaaccgccca taaaggcgaa ctcgaatgcc
    45181 gcagcgacaa ccggcattcc atacagggtg cctttcatca ccaccagcgc atctttttcg
    45241 ccggtttctt tctgcgcaga tgccagacgg tctttatact tcttggagtc acgaaacttc
    45301 agcacatctt tcggctcaag ctcgctaccc aactccacaa ggcttccttc atctaacagg
    45361 ctatgcaggc gattacgcgc tgtcatacgc atgtgatggt cacacttcgg acagacctca
    45421 agattacgtt ccagctcagc gcggtataaa acctgaccgc agctatcaca cttagtccac
    45481 accccttcag gaatgctcgc cttgcgggtg ggagtaatgt tgcttttaat tcgttcaatc
    45541 cagctcatta gggacctttc tgtctgaacc tggttcgatg ccagttttat ctttggggac
    45601 gcataatgcc atttttgccc ccaacagacc atgaatgttg cacattaaaa cataacagcc
    45661 cgaaactttg gataaaaaag tggtcgaacc gcggagttac tttttatttt gcggcgcgtg
    45721 ccgcagcgcg tttgtggcga ataaattcga aaacacctgg caatattgaa acaaaaataa
    45781 tgccaacaat catcagttta aggttgctct gaatgaaggg gagcgttccg aagaaatagc
    45841 ctgcgtaggt aaaaagcagt acccacaaca gtgcgccgat cacgttataa gcggcgaaat
    45901 gacggtacga catgtggccc attcccgcaa caaacggggc gaacgttctg acgatcggca
    45961 caaaacgggc gagaataatc gttttgccgc catgtttctc ataaaactga tgagtcttat
    46021 caagataact gcgacgaaag attttcgaat ccggattact gaacagtttg tcaccaaata
    46081 accgtccaat ggtgtagttc accgcgtcac ccacaatcgc ggcgatcagc atcagcacca
    46141 ccatcatatg gacgttgaga tcgttggttt ccagtgatgc caacgcaccg gcaacaaaca
    46201 gcaatgaatc acccggtaaa aacggcgtta ccaccaaacc ggtttcacag aacaaaatta
    46261 agaacaaaat ggcataaacc cagacgccat actccgcgac cagttctgcc agatgcacgt
    46321 caatgtgcag gataaaatcg atgaggaaat aaatcaggtc catattagcc tatgccttgt
    46381 actcgtcatc tttcaggctg taactacgtt ggctacagcc tgaaatgttc cgagcattat
    46441 tcttgttagt ccgccagaaa tagcgggccc attggcggtt ttggaagatc ataccggtca
    46501 gggtaatcca ccgcgaccag atacagccct tccgcttttg ccgttgctgc cgccagcgtt
    46561 ctgtcctttg ccgccagcaa ctctgctatc cagctctccg gctggttgtg ggcaccgact
    46621 tccatcaggc tgccgacaat attcctgacc atatgatgta caaaggcatt cgctttgata
    46681 tctaccacca cataaggacc gtgacgcgtg acattaatat gcataacgtt gcgccacggg
    46741 gttcgggatt ggcactgcac cgcacggaac gaggtgaaat cattctcgcc cagcaagcat
    46801 tgcgcggccc gatgcatccg ttcagcgtcc agcggttcgt aaaaatgggt taccccttta
    46861 ctcagtaccg ccgggcgcag ccgatgattg tagatgatgt agcgataacg gcgagccgtg
    46921 gcgctaaatc gggcatgaaa atcatcaggt acagctttaa cccaacgcac ggcgatgtca
    46981 ccaggtaaat tcgcatttac gcccaacgtc cacgcagcgt ctttgcgctg cgcggtcgtt
    47041 tcgaaatgca caacctgccc ggtgccgtgt acacctgcgt cagtacgccc ggcgcagaag
    47101 acggtgatcg gttcgttcgc cacctgggag agcgcctttt ccagcttctc ctgcacactg
    47161 cggacttcgt tctgccgttg ccagccgtaa tacttactgc cgtcgtactc aatgcccagc
    47221 gcaattttat aaactggcgg ttgttgctgg tcggacatta gtacagatac tcctgcacca
    47281 gtttctcggc gatttttact gccatcagcg cgccgccaaa gcgaacgtta tcggccaccg
    47341 accagaactg aacttgctcc ggcataccgt agtcattacg tacgcagcca acggaaagat
    47401 gcggcgtacc agaagcatcc cccacctgag tcgggaattc gttctcttca gagagcacaa
    47461 tatcttcgcc ctgagcaaac gcatcacgcg cttcttctgc cgccagcgga cgcagagctt
    47521 caaagttgac catctgggca tgaccgtaga ataccggtgc ctggacgacg cttgccgaaa
    47581 tcatcagccc ttcgtcctgc aggattttgc gtacttcgtc aacgatacga cgttcttcac
    47641 gcacgctacc ttcgctatcc ggcagtaacg gcagcatgtt gaacgccagc tgacgcccga
    47701 agaaatcttc ttcatcaatc ggaatgccgt tgagcaattt agcactctgc cccgctaacg
    47761 catcgaccgc ttttttgccc tgggcggagg ctgaaatcag gctggtaacg ctgatacgcg
    47821 acaaaccgcc ctgatcgatt aacggtttca gtgccgccag cagctgactg gtcagactgt
    47881 ctggtacggc gatgacattc cggttgcggt aatcggtcag tacaaacggg tttacttccg
    47941 gcaccaccag cggtacgtcg ggttcgagag caaacaatcc gctgctgtcg atcaccaggc
    48001 aacctgagtt ggtcgcttct tcaacccagg cagcggtagc ttctttgcct gcgacaaaaa
    48061 acgccagctg cgcctgcgtc cagtcgaatt cagcggcatc ctgcacggtg attgtcttac
    48121 caccaaagcg cagttgttcg cctgcgcttt cgttacgtgc cagtgcataa atttccccaa
    48181 ccgggaactg acgttcagcc agcgtttcaa gcagggcttc gcccacagcg ccagttgcgc
    48241 ccaggacggc aatgttccag ccttcagaca tggtggttta ctccagaaat agcaaagctc
    48301 cctgccaata ttacagcaga gagcatgaag aagagattaa cgtgccggat gatgaacggc
    48361 gttaaaaccc agtttacaca gcaatgatgc cgcgctggcg tcatcacaaa ttacatacag
    48421 agatgaccat tcacggcgct caagatagtt tttgcgcagc ttatcgaact cacccggtat
    48481 tccggcgact ttacgcagcg gtgcgtcatc gcggcgcaca tcatacacca aatgcaccag
    48541 ccttttcagc gtcggttgat cgagcgggcc atgcagcgta atgcggccaa actctggcgc
    48601 gggcagcaac gtatccagcg caacgtgttg ttcatgccca ataaacttgc tataagcttc
    48661 aaacacttgc gtagtaccgc gtgctttacc ttccagggta tagcctgcga tatgcggcgt
    48721 gccgatatcc acttttttca gcaattccac gttgagttcc ggttcgcctt cccagacatc
    48781 cagcactacg cttaacttct ggccttcgtt cagacaggtc aatagggcag tattatcgac
    48841 gactgcgcca cggcaggcgt taatcagaat cgctccgggc ttcaggctac ggatcagttt
    48901 ttcatccgcc agatgtagcg ttttgtacgg accatcttta aagagtggcg tatggaaagt
    48961 cagaatatcc gcatgctgaa ctaattcatc cagcgagcgg aaatcaccct catccccacg
    49021 gtcggcgcga ggcggatcgc aaagtaaggt tttaatccct aacgcttcca gtcgtgcctg
    49081 taaacgccga ccaacgttac caacgcccac gatccccacg gtacgctcgc gcagtgaaaa
    49141 tccatcgcgt tcggcaagca tcagcaggga ggagaaaaca tattccacca ccgcaatcgc
    49201 attacagcca ggtgccgcgg aaaaaccaat tcccgcctgc tttaaccacg cttcatcgac
    49261 atggtcggtc cccgcggtgg cagtgccaac aaatttaatg ggttttcctg ccagcaaaga
    49321 ttcattcact ttcgtgaccg aacgcaccat cagcgcatcc gcgtctgcca gttgagcgac
    49381 ggggattgga cgcccgggaa ccgcggtcac ctcacccaaa cggctaaata agtcgcgggc
    49441 ataaggcata ttttcatcaa caaggatttt cacgtttgtg ttacctgtat gagacgagag
    49501 ttaaccggac aagtgtgcca taatctcgcg gccaggcata cttgcgaaga tttcaggtat
    49561 aaggatacgt aatgatacaa cctatttccg gccctcctcc tgggcaacca ccaggtcagg
    49621 gagataacct gccgtctggc gcgggcaatc agtctttatc cagtcagcaa cgtacttcgc
    49681 tggaaagctt aatgacgaaa gtgacctcac tgacgcaaca gcaaagagca gaactgtggg
    49741 cgggtatcag gcacgatatt ggtctgtcgg gagattcacc gctgctttcg cgtcacttcc
    49801 ctgccgctga gcacaatctg gcgcaacgtc tgctggccgc gcaaaaaagc cattctgccc
    49861 gccagctttt agcgcaatta ggggagtatt tacgtctggg gaataatcgt caggcggtca
    49921 cggattatat ccgtcataac tttggtcaga cgccgctgaa tcagctctca ccggagcaat
    49981 taaagaccat tctcaccctg ttgcaggaag ggaagatggt tattccgcaa cctcagcagc
    50041 gcgaggcgac cgaccgtccg ttattaccgg cggagcacaa tgcgctcaaa cagctggtga
    50101 ccaaacttgc ggcggcaacg ggagaaccca gcaagcagat ctggcaatcg atgctggaac
    50161 tttccggggt gaaagatggt gagttaattc cagcgaaact gtttaaccat ctggtgacct
    50221 ggctgcaggc gcgtcagacg ctaagccagc aaaatacgcc gacgctggaa tcactacaga
    50281 tggcgctgaa acaaccttta gatgccagtg aactggcggc gttatcggca tatatccagc
    50341 aaaaatatgg tctttctgcg caatcatcgc tttcttcagc ccaggccgag gatattctta
    50401 atcagcttta tcaacggcgg gttaaaggga ttgatccgcg tgatatgcaa ccgctgctta
    50461 atccttttcc accgatgatg gacacgttgc aaaatatggc aacgcgtccc gcgctgtgga
    50521 tactgttagt cgcgattatc ctgatgctgg tctggctggt tcgttaaccc cgacgaaacg
    50581 acagtatcgt gacaataatt cccagcaccg cagagatcgc cccggcaaga aataccgaag
    50641 agtaaccaaa cgtggtcgcc agcattcccg ccagcggccc ggagacgccg agggcgatat
    50701 cctgaaacgc ggcgtaaccg cccaatgcgg tgccgcgaac ttgtgagggg acgcgtttaa
    50761 ccacctccac gcccagcgca ggaaagataa gcgaacatcc ggctccggtt aacgccgcgc
    50821 ccgctaatgc gacccacgca ccaggggctt gccagagcag caacaagccc accgtttcta
    50881 caagcagaga gacaatcgcc actttcacgc cgccaaaacg gtccggcatc cagccaaaca
    50941 tgacacgcat cacgacaaat gcgccgccaa acgcggtaag agtaaagccc gccatcgccc
    51001 atcctttgct ggcaaagtag agcgaaacga aagtcccgat aaccgcaaaa ccaacgcctt
    51061 gtagtgccag acctaaccca ggtttccaga taagcccgac aacactccac agcgatggac
    51121 gttctcccgc cagggccggt actttgcgca ctgtgccgtt acaggcccac gccagtaagg
    51181 gtaatgccat tgtggtgagc gccagtgcgg caaaaccgta atggctatga atcaacaggc
    51241 caagcggcgc accaacagcg agggcaccgt aaatcgccat tccgttccat gacatcactt
    51301 tgccggaatg ttttggccca acgatgccta atccccaggt cagagcgccc gtcagtaact
    51361 ggctttcacc aaagccaaga atcaaacgcc cgacgaccaa cagggcaaat ttgaacggtg
    51421 cggagacggg caaaatcgcc gccaacagca gcgcgccgcc agccagacca caagctaaca
    51481 tcccctgaag cgccgaacgt tttgcgccat attgatcggc cagtcgcccg gcatagccac
    51541 gcgtcagcac cgtagccaga aactgaatgc cgacggcaat cccgaccatg gtgttgccat
    51601 agcccagttc atgatgaaca aacagcggga taaccggcaa cggcagccct acggtcatgt
    51661 aggtgagaaa aaccgcaaaa gcgatgcgga agagcgaaaa attggcagaa gatcgtgttt
    51721 cggtttggct tacagcagtc atgcattact ccagaatgca gcgcaaggcg aggagtctcc
    51781 ccgtctcatc tctctggttt tcagggttac ggtgcgttgg caggatttaa cgcgtacgtc
    51841 ttttcagaag gaaatcgaca aagcgggaag tttgcctgga acaggcggcg attgtcaata
    51901 atgtgaaaaa gggaaccatc aggttccctt ttgcgttagt gtcggatgcc gcattggcgc
    51961 gtaatgttgg atgcgacgct ggcgcgtctt atccgaccta ctccggccta ctgcgaatta
    52021 atctttcagc ttgcgcatta ccagcgtggc gttggtgccg ccgaagccga agctgttaga
    52081 cataacggtg gtcagttcgc gatcggtcgt ttcggtcacg atgttcagac ccgcagcctg
    52141 ctcgtccagc tcttcaatgt tgatgctcgg ggcgataaag ccgtgttcca gcatcagcag
    52201 agagtagata gcttcctgta cgccagcagc gcccagagag tgaccggtca ttgctttggt
    52261 tgcagaaatc gccgggctct tatcgccgaa tacttcacgg atagccgcca gctctttcac
    52321 gtcgccaacc ggagtcgaag taccgtgaga gttcaggtag tcgattgggg tatcaacacc
    52381 gtgcatcgcc atcttcatgc agcgcactgc gccttcgcca gacggagcaa ccatgtctgc
    52441 gccatcagac gttgcgccgt agccaacgat ttcagcgtag atatgagcac cacgtgccaa
    52501 cgcgtgttcc agttcttcga ccaccaccat accgccgccg ccagcgataa cgaaaccgtc
    52561 acggtgagcg tcataagtac gggaggcttt ttccggggtg tcgttgtatt tggtagacag
    52621 cgcacccatc gcgtcgaatt cgcaagccat ttcccagcac agctcttcgc cgccgccagc
    52681 aaacacgatg tcctgtttgc ccagttggat ctgctctact gcgttaccga tacagtgtgc
    52741 ggaagtcgca cacgcggagc tgatggagta gttaacgccg tgaatcttaa acggcgtggc
    52801 gaggcaggca gaaacgccgg atgccatcgc tttggtgacc acatacgggc ctaccgcttt
    52861 caggccgcgc gggccgcgca ttgcgtcagc gccgaacacc tgaaaacgcg gggaaccgcc
    52921 gccggaacct gcaatcaggc caacgcgcgg gttattctgg taagcttccg gggagaggcc
    52981 agcatctgca attgcctgct ccatagaaag gaatgcataa atggatgcgt cgctcataaa
    53041 gcgcacaact ttgcggtcaa tgaggccagt ggtatccagt tttacgttgc cccagacgtg
    53101 gctacgcatg ccggaatcct tcagctcctg agagaaagtg atccctgaac gtccttcacg
    53161 cagagatgcc aggacttcct gctggttatt accgatgctg gaaacaatgc ccaggccagt
    53221 aatcactgca cgtttcattc aatacctctg taagtcgcac atagagtaag tttcgaatgc
    53281 acaatagcgt acacttgtac gccgaacaag tccgatcagc caattaatag agaaatttgc
    53341 gcagcctgac acacatcgct aagatcgagc caccgcctgt aagacgagta acttacgtga
    53401 aacactactc catacaacct gccaacctcg aatttaatgc tgagggtaca cctgtttccc
    53461 gagattttga cgatgtctat ttttccaacg ataacggact ggaagagaca cgctatgttt
    53521 ttctcggagg taaccaatta gaggcacgct ttcctgagca tccacatcct ctgtttgtgg
    53581 tagcagagag cggcttcggc accggattaa acttcctgac gctatggcag gcatttgatc
    53641 agtttcgcga agcacatccg caagcgcaat tacaacgctt acatttcatt agttttgaga
    53701 aatttcccct cacccgtgcg gatttagcct tagcgcatca acactggccg gaactggctc
    53761 cgtgggcaga acaacttcag gcgcagtggc caatgccctt gcccggttgc catcgtttat
    53821 tactcgatga aggccgcgtg acgctggatt tatggtttgg cgatattaat gaactgacca
    53881 gcaaactgga cgattcgcta aatcaaaaag tagatgcctg gtttctggac ggctttgcgc
    53941 cagcgaaaaa cccggatatg tggacgcaaa atctgtttaa cgccatggcc cggctggcgc
    54001 gtccgggcgg tacgctggcg acatttacgt ctgccggttt tgtccgccgc ggtttgcagg
    54061 acgccggatt cacgatgcaa aaacgtaagg gctttgggcg taaacgggaa atgctatgtg
    54121 gggtgatgga acagacatta ccgctcccct gctccgcgcc gtggtttaac cgtacgggca
    54181 gcagcaaacg ggaagcggcg attatcggcg gtggtattgc cagcgcgttg ttgtcgctgg
    54241 cgctattgcg tcgcggctgg caggtaacac tttattgcgc ggatgaggcc cccgcactgg
    54301 gtgcttccgg caatcgccag ggggcgctgt atccgctctt aagtaaacac gatgaggcgc
    54361 tgaaccgctt tttctctaat gcgtttactt ttgctcgtca gttttacgac caattacccg
    54421 ttaaatttga tcatgactgg tgcggcgtca cgcagttagg ctgggatgag aaaagccagc
    54481 ataaaatcgc acagatgctg tcgatggatt tacccgaaga actggctgta gccgttgagg
    54541 caaatgcggt tgaacaaatt acgggcgtta cgacaaattg cagcggtatt acttatccgg
    54601 aaggtggctg gctgtgtccg gcagaactaa cccgtaatgt gctggaacta gcgcaacagc
    54661 aaggtttaca gattcattat caatatcagt tgcaggattt atcccgtaag gatgactgtt
    54721 ggttgctgaa ttttgcagga gatcagcaag caacacacaa tgtagtggta ctggcgaacg
    54781 ggcatcaaat cagcggtttc agccaaacat cgactctgcc agtgtattcg gttgccggac
    54841 aggtcagcca tattccgaca acgccggaac tggcaaaact gaaacaggtg ctgtgctatg
    54901 acggttatct cacgccacaa aatccggcga atcagcacca ttgtattggt gccagttatc
    54961 atcgcggcag cgaagatacg gcgtacagtg aggacgatca gcagcagaat cgccagcggt
    55021 tgattgattg tttcccgcag gcacagtggg caaaagaggt tgatgtcagt gataaagagg
    55081 cgcgctgcgg tgtgcgttgt gccactcgcg atcatctgcc aatggtaggc aatgttcccg
    55141 attatgaggc aacactcgtg gaatatgcgt cgctggcgga gaagaaagat gaagcggtaa
    55201 gcgcgccggt ttatgacgat ctctttatgt ttgctgcttt aggttcgcgc ggtttgtgct
    55261 ctgccccgct gtgtgccgag attctggcgg cgcagatgag caacgaaccg attccgatgg
    55321 atgccagtac gctggcggcg ttaaatccga atcggttatg ggtgcggaaa ttgttgaagg
    55381 gtaaagcggt taaggcgggg taatctcctt tggcagtgtt tgccggatgc ggcgtgaacg
    55441 ccttatccgg cacattactt actgctgtga cgcctgctga aacaggtttt cccacatatc
    55501 ggtcaccagc gcctggtcac gcggcgacaa ctcaccggca ccaatggctt tttccagact
    55561 ctggctaacg gttgtatgta ccgcctgggc ggagtggtca tcaccacttt ccagttctgc
    55621 gatggctaat gtcaggtggc cacgcaaata cccactggca aacaactcat catcactggc
    55681 atggtcaacc ataccgtcga ttaatgccag aatgcgtgat tcaaactccg cgatcatctt
    55741 ctttcctcat tgtaaaacgt ggcgctggct ttagttgagc gcttccggcc acgggaactg
    55801 ttccgccgtc agtgccggcg tgtgataata attttgtaat gctttaatga agcgtgccgg
    55861 gcgttcagga atgccgtttt ccagataatc catcacctgt gcatgtaccc gccgttgaaa
    55921 taccacgcgg tccggttcga aatccccttc cagattgtcg cagctaacat taaacggata
    55981 tcccgccgcc acacagaaca accagtcgaa cgcctgcggc ttcacttcaa catcttcaaa
    56041 ctggctttgc gtttgggcat cgcgtccgtc cgggcaatac cagtagccga aatcaaccag
    56101 ctcacggcgc gctttcccgg caatacacca gtgcgaaatc tcatgaattg cgctggcata
    56161 aaagccatga gcaaagacga ttcggttata cggtacttcc gcatcagcag gaagatagat
    56221 cggttcgtcg tcgcctttaa tcagacgggt attaaaatca tcggcaaagc agctattaaa
    56281 aatttcaatc aactgctcat agtggtgtgt actgttcatt agttaatccc caaccagtgg
    56341 aggatctcct gtccgtggct atcgtaaagt aatttggcac tcatcaccgc tgagacaata
    56401 acaatcatcg ggcggatcag cttttgtcct ttgctcaaca ccagtcgtga acccatgcgc
    56461 gcgccgagga actgccccac cagcatcacg aatcctgtcg cccaaatcac tttgccaccg
    56521 agaataaaca gcagtaaacc gccgatattt gacgttgcgt tgagtaattt ggcgtgagcc
    56581 gtggctttgg cgaggttgaa tccgcacagc gtaacaaagg ccagcgcgta aaacgatccc
    56641 gctgccggac caaagaagcc gtcataaaaa ccgacgcagc caccggcaat taacgcgaag
    56701 ggtaaaccgt acatccggcg ctggcgatct tcttcaccca gctttggcat cagcaagaaa
    56761 tagaggccga tacaaatcac cagaatgggc aaaatctgcc gtaagacatc agcctgaaca
    56821 tactgcacca gcaatgcgcc gctcattgag ccgacaaagg tcatggcgat attgagtttc
    56881 tgatcgctta aactaaccac tttgcggcga ataaagtaga tagtggcgga aatagagccg
    56941 ccgcaggctt gcagtttatt ggttgccagc gcgttagcgg gagacatccc cgccgccatc
    57001 aatgccggaa tagtgagtaa cccaccgcca ccggcaatcg agtcgataaa tcccgccagc
    57061 atggcgacaa aaaagagaac tcccagcaac agcggggaaa ccataaacag gctattaaac
    57121 gtttccatta gatcacgtgc tcatccagta gcgcctggca ggaaggcggc aacggaggcg
    57181 gtgtcttctt ctcaggcttt gttgttcccg gttttggagg ttcaaaccag ctttgcagtt
    57241 ctgccccgca accatcgccc ggtggcggta aaggttgatc ttcacactcc agactatcgg
    57301 caggacaacg taatcgtaca tgcatatgcg cgcgatgctg gaaccagggt cgcactttgc
    57361 gcaaccagtc gcgatcggtg cccgcatcaa ggcaaagttg ttgtttaatc gccggattaa
    57421 caaaaatgcg tgtgacgtct ttgtcctggg cggcgagttt gatcaagctg aaaatttccg
    57481 gcttccacag cgtcgggaca acgtgtttac cgtcgcggga aactaaatct aacgcttgcg
    57541 ggcgcaagag ctgcgcggag gtccagcgtg tttttggcag ttgcaggaag atgtccacat
    57601 ccagtccggt ctggtggctg gcgtgaccgc cgttgaaacg accaccagca ggcatcccca
    57661 tatcgccaat cagcaccgtg cccaagctca gattgctcac ctggctactc agacgctgga
    57721 taaacatcac cagatccgga tgtccgaaat agcgacgctg atcggtacgc atgacctgat
    57781 aatgttcgga ctgtatcggc agcgtgtcag cgccgacgat acaaccatta gaaaaactgc
    57841 ctatcgattg tgcgctaccc ggcacaggtt gggttatttt ttgccacggc gtcgctgcca
    57901 ggctggcgct actggcaagc agggccagca gcgcaatcgc ggttttgttc attttttacc
    57961 agcgtggaat atcagtcttc acatcggcat tttgcgcccg ttgccgtaac aggtgatcca
    58021 tcaaaacgat cgccagcatc gcttctgcga tcggcaccgc acggatccca acacaaggat
    58081 cgtgacggcc tttggtgatc atctcaactt cttcgccaaa gcggttaatg gtacgccctg
    58141 gcacggtaat gctggaggtt ggcttcagcg ccatatgggc aatgatttgc tgcccgctgc
    58201 tgatgccgcc aagaatgccg cctgcatggt tgctctggaa accgtcttta gtgatttcgt
    58261 cgcggttctg gctgccacgc agcgccacca cgtcaaaacc atcaccaatt tctacgcctt
    58321 tcaccgcatt gatgctcatc agcgcatggg cgatgtcggc atccaggcgg tcaaagaccg
    58381 gctcgccaag tccggcgggg acgccactgg caacaacggt gactttcgcg ccgatggagt
    58441 cgccctcttt tttcagcgcg cgcatcagtt catctaacgc gtcgattttg tccgggtccg
    58501 ggcagaaaaa cggattttgc tcgacctgcg accagtcttt gatttccagc ggaatgtcac
    58561 ccatctgggt caggcagccg cgaatctcaa tgccaaattt ctcggcgaga tatttttttg
    58621 caatcgcccc tgccgccacg cgcatggcgg tttcacgagc ggaagagcgc ccgccgccgc
    58681 gataatcgcg cagaccgtat ttttgttcgt aggtgtaatc ggcatggcct ggacggaaaa
    58741 cgtctttaat ggcgctgtaa tcctgagaac gctggtcggt attttcgatc aacaagccaa
    58801 tgctggtgcc ggtagtaacg ccttcaaaaa caccggagag aattttgacc tgatccggct
    58861 cacgacgctg ggtggtgtag cgcgatgtcc cagggcgacg acgatcaagg tcatgttgca
    58921 ggtccgcttc cgtcagcgga atgcctggcg gaacaccatc gacgatgcag ccgagcgcca
    58981 gcccgtgcga ttcgccgaag gtggttacgc gaaagagttg tccaattgtg tttccagcca
    59041 tcacggctcc gttattgttg tgtttgcgtg tttacttaat ctttataaat cgcgaaatgt
    59101 tcacgggccg ccagcagctg ctctttggtg agcataaaca caccatcgcc gccgttatca
    59161 aactccagcc aggtgaacgg aacatccgga tattgttcca taagatgtac catgctgttg
    59221 cccacttcac aaatcagcac gccatcatca gcgaggtaat ctgccgcgtt tccgagaatg
    59281 cgacgcgtca gtttcaggcc gtcggtgcca gatgctaggc ccagttccgg ctcgtgacgg
    59341 tattcgtttg gcaggtcgga catatcttcc gcatcgacat acggcgggtt agtgacaatc
    59401 aggtcgtact gcactttcgg taaatcacgg aacagatcag agcgaatcgg aatgacgttg
    59461 tggatcagac cgtgttcttc gatgttctgt tcagcaaccg ccagcgcgtc gggagagata
    59521 tccaccgcgt caacttccgc atccgggaag gcataagcac aggcaatggc gatgcagccg
    59581 ctaccggtac acatatctaa aatatgctgc ggttgcttgc tgataagtcc ggcaaattta
    59641 ttgttgatca attcaccaat cggcgagcgc ggcaccagca cacgttcatc gacgtaaaat
    59701 tcatgaccgc agaaccacgc tttgttagtc aggtaagcca ccggaatgcg ttcattgacg
    59761 cggcggatca cgcgctcaac aatacggtgt ttttcgctgg aggtcagacg cgcggtgcgc
    59821 atatcttccg ggatatccag cggcaggtag agtgaaggca acaccagttg cacggcttca
    59881 tcccacgggt tgtcagtgcc gtggccgtac cagatattcg ccgcgctgaa gcggctcacc
    59941 gaccagcgca acatgtcctg aatggtttgc agctcattta ctgcttcatc aacgaaaatt
    60001 ttatccacgt attcctccag ggcatgatcg caataatttc ggcggctagt ttgccatgaa
    60061 gatgacgata aatcagcatt cacgcgcggt gagtgaggaa aaatacgttt aaaacgatcg
    60121 attgcgctac gagtcgggta aactgtagga aaattagaaa tagagacaga taaatgaaaa
    60181 agaaaacaac acttagcgag gaggaccagg ctctgtttcg ccagttgatg gcggggactc
    60241 gcaagattaa gcaggacacg attgtccacc gaccgcagcg taagaaaatc agcgaagtgc
    60301 cggtgaaacg gttgattcag gagcaggccg atgccagcca ttatttttcc gatgaatttc
    60361 agccgttatt gaataccgaa ggtccggtga aatatgttcg cccggatgta agccattttg
    60421 aggcgaagaa gttacgccgt ggcgattatt caccggagct gtttttggat ttgcacggtt
    60481 tgacgcagct gcaagccaag caggagttag gcgcattgat tgccgcctgt cgccgcgaac
    60541 atgtgttttg tgcctgcgtg atgcatggtc atgggaagca tattttgaag cagcaaacgc
    60601 cgctgtggct ggcgcaacat ccgcatgtga tggcatttca ccaggcacca aaagagtacg
    60661 gtggtgatgc ggcattgctg gtgttgattg aagtggatga gtggttgccg ccggaattac
    60721 cgtgaatgct ggcatcgaat gcctgataag acgcttcagc gtcgcatcag gcatcagtgc
    60781 acaacgacga gctactacag catattcagt acgtactgga atcgacaggt agaatcaata
    60841 ggttgccgcg aggtggtatc cacgcgaagc accatatcat gaagctcttt gtcggtaatg
    60901 gggtgacgat ttggtgttac cgtcactttg gcattgtcac agcccgatga ggtgaaggtg
    60961 agcatctgcg acacccaacg acaataagca ccacgatcgt cagtatcacc aaatttgctg
    61021 ccgtcacaca gtttgccgtc tttcatcagg taggtggaga gcgttttttc aattatcccg
    61081 ccggtagact ggagcgctaa cgtcttatca tgcacaaccc gactttcatt ccaggagaca
    61141 tcataaggcc ctaacggtat aggtggacaa gaagagttac tgactgtgcg tccggaatag
    61201 gttcccggag caggatcaat aagatcaatg ctatctgcat gtgtcgatac cagccacggg
    61261 cagccatgaa cgctggagtc ttccttccag acttccattc gtatttcata acaagtccac
    61321 atcgtccttt gcgcacggct gtcatactct gcaagccccg gacaagatga ttgtgatatc
    61381 gctgtcatcg atatgacttt taatgatggt gcagggccag gtcccgtcca gcttttcaaa
    61441 ggtatccatc cagtgattaa accggtgtta tttggtgtct cataaacacc gtgattgacg
    61501 ctatcggggg taagaacatc aagataataa gttatcttcg tagaatagct tgcataccct
    61561 atcggtgtat acattgttgc aacaatgaca ttcgcctgaa ctgctgtact gaagaaaagt
    61621 gatatcagca ggcccaaaat ccagcgcatt attttcatct taaatatact caaacgttgc
    61681 ggttaactgg gcggtaaaat taccaggtgt tacatcacgc ccctcttttg cctgtaacca
    61741 tgctctgaaa ttaagactgt tattgccatc attcagcaca aaggtcactc ccgtcgtgtt
    61801 attaatagca acagcagtac catcagtagt ttccatacca atgcctacgc cctgtgcacc
    61861 agaggtatca tccagagcca gaaatcccgg ttgcccactg tcttctgttc cggtcagagt
    61921 aacttttacg ctgtactgcg ctggcccacg gcaatctttc aggcgaaaaa ccaccggtac
    61981 acgatcggac tgaccgcgca ccatcaaatc tttgtggcta atattcgcaa actgtacctc
    62041 tgccaacgtt ccagcctgtt ccaccggagt acaggttttg ctcatcaggt tgccgtaaaa
    62101 atgcaaatta ttagctgcca gtgctgaatg actcgccagc accagcacac cgcccaacag
    62161 aaaggtttgc accctgatac attgatattt cttcagtttg ttcattgata atccacctgc
    62221 aatgtggcgt aagcggaaaa gttaccgtca gtcagcgtgg catcggaagc ttttacaggt
    62281 gcggccttca acttcggcag gttggcgggt gtcacgttaa gcggggtatt cagcttaaag
    62341 ggctgaccgt tttgctggag ttcaatccct aatcccgtga catccgtctg aatcgccgca
    62401 tcgttatagt tggtctgtgt accggtccag gttagcgtca ttacccaggc gtcatcggta
    62461 atatcagggt cacacgttat ctggtacgga acatctttgc ggtaattaac cccgtcaata
    62521 ttgtcgataa tgacgtcgat aaactggatc tcaatatcat caccattgct gacggtgcag
    62581 accggaggtt cgatcagcgt acccgtgaag gtgatatctt ccggtgcggc atgcgttatg
    62641 gtgcaaaaag cggataataa aattaacgag agtcgtttca ttggtaatcc accaccattg
    62701 tcatgctggc gttaaactgt gcgcctgtca gcgtcacgcc attctgtttg actggcactg
    62761 cttttagttg tggctggcta ctgacgctaa atggagtcca ggtattgtcg ccaatcgcaa
    62821 acagagagtt atctgctgca ttttcaatac gaatgccaaa cccggtaatt cccgtgctta
    62881 acaccgtttc gccattgatc gtggtggttg tgcccttaaa ctgcatctga aggtcatcgc
    62941 tcaggctatt ggcacagttc agggtataac ctgcatcttt gcgatattca gtaccattga
    63001 tttttttgat gatcacatca ccaaaatcga cgttactgcc ttttacggta caaggaggtg
    63061 gtgggtctac cagtacgcgc aatgtcaatg gcacactttt cgtttcaccg gcaagagcac
    63121 tgcccgtaag cagcactcct cccagcccgg ccaaaagtag tcgtttcatc tcacactccc
    63181 ggcctcagcc tttgcggctc tgctcttcat caacctggca actgttaccg ttgcaggtga
    63241 aaaagagcgg catccgagcg ccatagtcgt tgacataggt cagtaccggc acactcccca
    63301 tcttcacatt cagcggtgca gaggttttcg gcgacatcac tattggcgag aaaccggctg
    63361 ccggattgcc atttttctgt gcgctggcat tactgaaaat gacgtaatac ggcgtcgggt
    63421 tattgacagt aaattcctga ccgttgcggg ttaaggtcac tttatgctgc cacgggtttt
    63481 gcgtggtgtt tttttccaga gctttcggtc gccagaaaag tttgatacgc gtctgaagag
    63541 cgatttgtag cgtgttggat ttgttcgatt tcggcggaat ttcgcgcacg ttgaaataga
    63601 acatcgattc ccgatcggca ggtaatttat gaatatccgg caggccctga attttaacct
    63661 ggccattcat cattgcttca atgcgctgta caggcggcaa taccgccagc ggcgagctga
    63721 tcttgacgcc cttttcatct tcaatccagc tttgcgccag ataaggcagt ttggggtcgt
    63781 tattacgcag cgtcacactg atagatttat cgctttcatt aaaaatcagg cgagtacgat
    63841 cgggcgttac tgacgcctgg gtagaaaaac ttaccgttgc tgccagtaac gacagtaccg
    63901 ttgtcaatgt tttggcagag agatatttag tcatggatca ttccttaatc acgttattgg
    63961 ttcgatgaaa cagacatcgg cggttccatt ggtgtcacct gttgtgtctg ctcctgaatg
    64021 acgggttgaa tatcatgcgg tatgacggga gaacttcccc ccttttgctg gcatggcaac
    64081 aacaagccat tgaacaggtc attcggtaac gggtctggca ggctgatatc gcagtgagat
    64141 tcaccctccc agaaaacggt catatgttca cccggtttaa cgcctgccag ataaacatta
    64201 ccttcgtcat caaccaaccc tacttgttgt tgattatcgt ttttcacttc cgccccaaat
    64261 ggcggatggc tgccatcctg caagcgcagc actgccatcg ccttctcacc gctgattacc
    64321 gcaaatttac ggtagccaat agcgccttcc gtcagcgttg cctgaaccac tgattttgta
    64381 gcttcagcgt tttccggcag tttgttcaaa tcgatataag cctggttgcg gtagtaatca
    64441 ttaacatctg ccaccaccgc tttgccgaac atgttggtat aaacggcgga accattacct
    64501 tcaaccggca cattagcaac gccatcagcg tcgattaaca gacgtgtacc gcccatgttt
    64561 tgtgtacgat gcagtgcccc gccatgagcg gtcagcgttg ccccgccctg taaagagatc
    64621 cctgctgagg tgtattgccc ttcatggtag ttggcactga gatccacttt tgccagagta
    64681 ccatcgtggc tgtagtagcc atccacgctg ctgtggtttt cgctggttcc ggcgcttaac
    64741 gtgtagtggc tggcgtcatc aatgcggtga tacagactca cctgattgct gtcggcaccg
    64801 ctgccatagt tgccgttgta actgatggtg ctgttgtcgc cccacggcaa acttaaggac
    64861 agataaacac ccttgtcagc acttttatcg tattcgtagc gataaccggt cagagaaacg
    64921 ctcaggttgc gaaggcttcc taaattaaaa taatgagaaa gcatcatgtt gtagttggtc
    64981 tgatcctggc gatcccagta ggtatggtgg gaatagttga gatagaccga aacgcgcgca
    65041 tccgtgaagt tctggttata ggtgaccgta tacatctctt tgtcgttacc ggtgcgcgcc
    65101 cggtcgtcgt cgttcgcatc cagatactcg ctcatggtca tgtagttttt ttcagagaag
    65161 cggtatccag caaacgtcac ccgactgttg agttcatcaa aatctttggc atagctgacg
    65221 cgataagagt tgccgtccag cgttttgttg ccatacacgc tgttatcgtc gagttgaaca
    65281 cgagagtgag tgacatcaaa cgctaacgcg cctagcagcg ccaggtcacg accgaggccc
    65341 agcgccgccg actggtagtt ttcatcggct aacgcaccgc cgtagagcga ccagccattg
    65401 gcaatccccc aggatgcctc gccgcccgag aagaagctac ctgcaacctg atggtcccag
    65461 ttttgtggac gccccattgt cactttgtaa cgcacctggc cggggcgagt caggaacggc
    65521 atggacgccg tgctgacgtc gtattcctgt acctggccgt tttgttcttc aatgcggaca
    65581 tgcagcgtgc cagagacgga atcgccaata tcctggatgc ggaatggacc tgcgggtacc
    65641 tgggtttcgt aaatgacacg gcccatttgg gttacggtca ctttagcggt agtgtgtgca
    65701 acacctgaaa tatcgggggc gtagccgcgc aggtttggcg gtaacatttg atcatcggta
    65761 ctgatgctgc cgccaatgta actgaagcca tcaaaaatat cggagttgag ataatcttcg
    65821 cccagcgaaa gtttggcttt taatgacggc aaggcgcgcc aggcgtagta acgactccac
    65881 tcccagtttt tttgcgtacc gctatcgtca gtgtcgccgt catcgttact gcgggtatgc
    65941 tgataatcgc tctgccagtc agctcgtaag cgccacggcc caacgttaac gccgaccgta
    66001 ccattaccgc agatgtcgtt agtgtcatca cccccatttt catgccgggt ttgcgcgttg
    66061 atactgtaat cggcaataag cccagggata ccgtcatccc agcgcgaagg cggatcccac
    66121 tcgctgtcgg tatattccag ataagcctgc ggtacagaaa caaggagtgc agactggcct
    66181 aaatcgccgc taatttctgt acctgctaaa agtgccgtat tcagacactg accatcgcgg
    66241 atccattgca aattctttgc aatatcttcc ttcagaccaa actgggcaac cagctctggc
    66301 gataagcagg catatgattt attcggatcg ttttcagttg cgtaccagta gatatcgtag
    66361 tcgtcaggta acggctgatt atttacatga acgcgtaagt tatattttcc cggttctaca
    66421 tagccttttt gcgaaaaacg gcccaaatca attttggtat tgccttttaa atcaagaaat
    66481 cggccatcaa actgaatggt atcgtctgcc agggcattaa atggacttcc agaaattgcc
    66541 agagcaatcc accacgaaag cccccgtaaa cggagaaaag aatgttctgg catcggcgta
    66601 tccatccatg attttttata atttagttat ttggtagtta taaaccccat aactttgcag
    66661 ctatggggga aatacattag agatacgtga tctggaacgt cgtcagcgtt tcaaacggtg
    66721 ccggtgttgg tgttacagca tccgtttcac ccactaacca tgctttaaag ttcagagttt
    66781 gtttaggctt gccttttccc gttgaactgt ccttcacgat aggttgctta atctctgctc
    66841 ccagtgcata acctgtaccg tgctggtcac cgataaccag gctaacgttt ggaatttcag
    66901 ttccattatc catgttagac agagaatagt tatctgcgtt agtggagtac ggattaccgg
    66961 tgaatgtggt agccattgtc gtttctgtat tgaaattaca gtcctgtaaa cgaatctgga
    67021 aatcttttgg tgtggttgtt ttgccgccgg ttaaagaacc cgtaccgatg ctgcccatat
    67081 ccacttccag tttatgatcg tcaggaacaa ttgagcacgg ggagtcttca attgtgccgt
    67141 aaaatctcac tgtaccgttg ttccctgcgg caacgactga tgctgaagtc agcgccccca
    67201 tgagcattgc cgtggcaact gctgctttta caaacttact cattatttgt ccttaaatca
    67261 taaataatta gaatataagc caactgaaat attgacgtag agcttcttca atttttacag
    67321 cgacttttaa gcagccaatg aacagatttt cagctcctga aaaaacaggt tccttgatat
    67381 aatattcttt ggcgtgccga acatgttgat attttaatat gactgatgca atttaaattt
    67441 tctaacattc aaagttagaa atacttaatt aatggacggg gataataatt actgaaattt
    67501 ttcatctcag ttatgaagaa tgagttcaaa aaaacggcaa atgcaaaaac tcagtgaata
    67561 aatcaaagtc aaaaacaatc acatggcaat gactatc
//
LOCUS       DACAOP010000014        66305 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.014, whole genome shotgun sequence.
ACCESSION   DACAOP010000014 DACAOP010000000
VERSION     DACAOP010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 66305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66305
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.014"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            339..2990
                     /gene="ppc"
                     /locus_tag="IT892_001027"
     CDS             339..2990
                     /gene="ppc"
                     /locus_tag="IT892_001027"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HAP3134266.1"
                     /translation="MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKS
                     SRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPE
                     VIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQ
                     LDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVP
                     NYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKAT
                     DLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARL
                     KGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVR
                     IDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAE
                     TREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETL
                     DDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIK
                     TCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLP
                     EITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDVYRGYVRENKDFVPYF
                     RSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQK
                     VVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKEL
                     RNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKE
                     GQEPDPRVEQALMVTIAGIAAGMRNTG"
     gene            3172..4905
                     /gene="cptA"
                     /locus_tag="IT892_001028"
     CDS             3172..4905
                     /gene="cptA"
                     /locus_tag="IT892_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HAP3134267.1"
                     /translation="MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTN
                     GIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLF
                     VMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
                     YGLILHPIAMNTFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNE
                     NNALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPNLT
                     VFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMT
                     ARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLNDPAPKKLIIVHLLGT
                     HIKYKYRYPENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAA
                     NPNGFLVYFSDHGEEVYDTPPHKTQGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFS
                     QDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKETTRWIGNPYKKNALIDYD
                     TLPYGDQVGNQ"
     gene            5120..5971
                     /locus_tag="IT892_001029"
     CDS             5120..5971
                     /locus_tag="IT892_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP3134268.1"
                     /translation="MYHDVSYLLSRLINGPLSLRQIYFASSNGSVPDLAYQVDFPRLE
                     IVLEGEFVDTGAGATLVPGDVLYVPAGGWNFPQWQAPATTFSVLFGKQQLGFSVVQWD
                     GKQYQNLAKQHVARRGPRIGSFLLQTLNEMQMQPQEQQTARLIVASLLSHCRDLLGSQ
                     IQTASRSQALFEAIRDYIDERYASALTRESVAQAFYISPNYLSHLFQKTGAIGFNEYL
                     NHTRLEHAKTLLKGYDLKVKEVAHACGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLT
                     EKPTTPE"
     gene            complement(5958..6299)
                     /locus_tag="IT892_001030"
     CDS             complement(5958..6299)
                     /locus_tag="IT892_001030"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HAP3134269.1"
                     /translation="MAYLVAVTACVSGVAHTYMAAERLEKLCLLEKWGVSIETQGALG
                     TENRLADEDIRRADVALLITDIELAGAEQFEHCRYVQCSIYAFLREPQRVMSAVRKVL
                     SAPQQTHLILE"
     gene            complement(6301..7179)
                     /locus_tag="IT892_001031"
     CDS             complement(6301..7179)
                     /locus_tag="IT892_001031"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418387.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[formate-C-acetyltransferase]-activating enzyme"
                     /protein_id="HAP3134270.1"
                     /translation="MTSSAGQRISCNVVETRRDDVARIFNIQRYSLNDGEGIRTVVFF
                     KGCPHLCPWCANPESISGKIQTVRREAKCLHCAKCLRDADECPSGAFERIGRDISLDA
                     LEREVMKDDIFFRTSGGGVTLSGGEVLMQAEFATRFLQRLRLWGVSCAIETAGDAPAS
                     KLLPLAKLCDEVLFDLKIMDATQARDVVKMNLPRVLENLRLLVSEGVNVIPRLPLIPG
                     FTLSRENMQQALDVLIPLNIRQIHLLPFHQYGEPKYRLLGKTWSMKEVPAPSSADVAT
                     MREMAERAGLQVTVGG"
     gene            complement(7145..9442)
                     /locus_tag="IT892_001032"
     CDS             complement(7145..9442)
                     /locus_tag="IT892_001032"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAP3134271.1"
                     /translation="MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRA
                     KATAYILEHVEISIRDEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFA
                     ISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIID
                     YPRLLNHGLGELVAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCT
                     DAQRREELLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYM
                     LPFYQTSLTQGEDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT
                     ENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIF
                     NDEVVVPAFLNRGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN
                     EGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR
                     DITDGGARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGE
                     KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVP
                     LGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVK
                     FTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA
                     GYSAFFVELSKEIQDDIIRRTAHQL"
     gene            complement(9493..9813)
                     /locus_tag="IT892_001033"
     CDS             complement(9493..9813)
                     /locus_tag="IT892_001033"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HAP3134272.1"
                     /translation="MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIG
                     LENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHL
                     AQTA"
     gene            complement(9828..10907)
                     /locus_tag="IT892_001034"
     CDS             complement(9828..10907)
                     /locus_tag="IT892_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HAP3134273.1"
                     /translation="MNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGA
                     VPDAVADPNLKKLFDIGVAGLTLMVPFLAAYIGYSIAERSALAPCAIGAWVGNSFGAG
                     FFGALIAGIIGGIVVHYLKKIPVHKVLRSVMPIFIIPIVGTLITAGIMMWGLGEPVGA
                     LTNSLTQWLQGMQQGSIVMLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAI
                     AAVGICIPPLGMGLATLIGRKNFSAEERETGKAALVMGCVGVTEGAIPFAAADPLRVI
                     PSIMVGSVCGAVTAALVGAQCYAGWGGLIVLPVVEGKLGYIAAVAVGAVVTAVCVNVL
                     KSLARKNGSSTDEKEDDLDLDFEIN"
     gene            11216..13717
                     /gene="ptsP"
                     /locus_tag="IT892_001035"
     CDS             11216..13717
                     /gene="ptsP"
                     /locus_tag="IT892_001035"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAP3134274.1"
                     /translation="MALIVEFICELPNGVHARPASHVETLCNTFSSQIEWHNLRTDRK
                     GNAKSALALIGTDTLAGDNCQLLISGADEQEAHQRLSQWLRDEFPHCDAPLAEVKSDE
                     LEPLPVSLTNLNPQIIRARTVCSGSAGGILTPISSLDLNALGNLPAAKGVDAEQSALE
                     NGLTLVLKNIEFRLLDSDGATSAILEAHRSLAGDTSLREHLLAGVSAGLSCAEAIVAS
                     ANHFCEEFSRSSSSYLQERALDVRDVCFQLLQQIYGEQRFPAPGKLTQPAICMADELT
                     PSQFLELDKNHLKGLLLKSGGTTSHTVILARSFNIPTLVGVDIDALTPWQQQTIYIDG
                     NAGAIVVEPGEAVARYYQQEARVQDALREQQRVWLTQQARTADGIRIEIAANIAHSVE
                     AQAAFGNGAEGVGLFRTEMLYMDRTSAPGESELYNIFCQALESANGRSIIVRTMDIGG
                     DKPVDYLNIPAEANPFLGYRAVRIYEEYASLFTTQLRSILRASAHGSLKIMIPMISSM
                     EEILWVKEKLAEAKQQLRNEHIPFDEKIQLGIMLEVPSVMFIIGQCCEEIDFFSIGSN
                     DLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVL
                     PLLVGLGLDELSMSAPSIPAAKARMAQLDSRECRKLLNQAMACRTSLEVEHLLAQFRM
                     TQQDAPLVTAECITLESDWRSKEEVLKGMTDNLLLAGRCRYPRKLEADLWAREAVFST
                     GLGFSFAIPHSKSEHIEQSTISVARLQAPVRWGDDEAQFIIMLTLNKHAAGDQHMRIF
                     SRLARRIMHEEFRNALVNAASADAIASLLQHELEL"
     gene            13729..14391
                     /gene="fsa"
                     /locus_tag="IT892_001036"
     CDS             13729..14391
                     /gene="fsa"
                     /locus_tag="IT892_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAP3134275.1"
                     /translation="MELYLDTANVAEVERLARIFPIAGVTTNPSIIAASKESIWEVLP
                     RLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIPGIVVKIPVTSEGLAAIKILKKE
                     GITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQTLLEMHAPES
                     MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTT
                     HL"
     gene            14402..15505
                     /gene="gldA"
                     /locus_tag="IT892_001037"
     CDS             14402..15505
                     /gene="gldA"
                     /locus_tag="IT892_001037"
                     /EC_number="1.1.1.6"
                     /EC_number="1.1.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418380.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional L-1,2-propanediol
                     dehydrogenase/glycerol dehydrogenase"
                     /protein_id="HAP3134276.1"
                     /translation="MDRIIQSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFA
                     QSTVEKSFKDAGLVVEIAPFGGECSQNEIDRLRGIAETAQCGAILGIGGGKTLDTAKA
                     LAHFMGVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLPNNPNMVIVDTKIVAGA
                     PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLLEEGEKAM
                     LAAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAVHNGLTAIPDAHHYYHGEKVA
                     FGTLTQLVLENAPVEEIETVAALSHAVGLPITLAQLDIKEDVPAKMRIVAEAACAEGE
                     TIHNMPGGATPDQVYAALLVADQYGQRFLQEWE"
     gene            15780..16397
                     /locus_tag="IT892_001038"
     CDS             15780..16397
                     /locus_tag="IT892_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1287 domain-containing protein"
                     /protein_id="HAP3134277.1"
                     /translation="MKASLALLSLLTAFTSHSLKSPAVPPTVVQIQANTNLAIADGAR
                     QQIGSTLFYDPAYVQLTYPGGDVPQERGVCSDVVIRALRSQKVDLQKLVHEDMAKNFA
                     EYPQKWKLKRSDSNIDHRRVPNLETWFSRHDKTRPTSKNPSDYQAGDIVSWRLDNGLA
                     HIGVVSDGFARDGTPLVIHNIGAGAQEEDVLFNWRMVGHYRYFVK"
     gene            complement(16424..17329)
                     /gene="yijE"
                     /locus_tag="IT892_001039"
     CDS             complement(16424..17329)
                     /gene="yijE"
                     /locus_tag="IT892_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418378.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine transporter YijE"
                     /protein_id="HAP3134278.1"
                     /translation="MSAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTAL
                     RCIFGALVLFIVLLLRGRGMRPTPFKYTLAIALLQTCGMVGLAQWALVSGGAGKVAIL
                     SYTMPFWVVIFAALFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAMLAILS
                     GVSWGASAIVAKRLYARHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTVFW
                     ALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEGS
                     GIVLIVLALALVSRKKKEAVSVKRI"
     gene            complement(17422..19602)
                     /gene="katG"
                     /locus_tag="IT892_001040"
     CDS             complement(17422..19602)
                     /gene="katG"
                     /locus_tag="IT892_001040"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HAP3134279.1"
                     /translation="MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVD
                     LLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIR
                     MAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
                     DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLG
                     ATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAG
                     PTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLF
                     KYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRR
                     FLNDPQAFNEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDI
                     IDLKFAIADSGLSVSELVSVAWASASTFRGGDKRGGANGARLALMPQRDWDVNAAAVR
                     ALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQDQTDI
                     EMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFD
                     GSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESKELFEGRDRETGEVKFTASRADL
                     VFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLDRFDLL"
     gene            complement(19931..20821)
                     /gene="metF"
                     /locus_tag="IT892_001041"
     CDS             complement(19931..20821)
                     /gene="metF"
                     /locus_tag="IT892_001041"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HAP3134280.1"
                     /translation="MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNS
                     IDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTI
                     ARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAK
                     SAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFK
                     QAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
                     LNRAEMSYAICHTLGVRPGL"
     gene            complement(21170..23602)
                     /locus_tag="IT892_001042"
     CDS             complement(21170..23602)
                     /locus_tag="IT892_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase II"
                     /protein_id="HAP3134281.1"
                     /translation="MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDM
                     MVVSAAGSTTNQLINWLKLSQTDRLSAHQVQQTLRRYQCDLISGLLPAEEADSLISAF
                     VSDLERLAALLDSGINDAVYAEVVGHGEVWSARLMSAVLNQQGLPAAWLDAREFLRAE
                     RAAQPQVDEGLSYPLLQQLLVQHPGKRLVVTGFISRNNAGETVLLGRNGSDYSATQIG
                     ALAGVSRVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPV
                     SGSEIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDVCLIEFQVPASQDFKLAH
                     KEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVADSALKILDEAGLPGELRLRQGLA
                     LVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSDDGISLVAVLRTGPTESLIQGLHQ
                     SVFRAEKRIGLVLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLSYD
                     GLDASRALAFFNDEAVEQDEESLFLWMRAHPYDDLVVLDVTASQQLADQYLDFASHGF
                     HVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVGAGLPINHTVRDLIDSGDTIL
                     SISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRDDLSGKDVMRKLVILAR
                     EAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNEQMVQRLEAAREMGLVLRYVA
                     RFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGA
                     IQSDINRLAQLL"
     gene            complement(23605..24765)
                     /gene="metB"
                     /locus_tag="IT892_001043"
     CDS             complement(23605..24765)
                     /gene="metB"
                     /locus_tag="IT892_001043"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAP3134282.1"
                     /translation="MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAH
                     DYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYG
                     GSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKIC
                     HLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDV
                     VTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLY
                     HPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLI
                     SHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG"
     gene            25042..25359
                     /gene="metJ"
                     /locus_tag="IT892_001044"
     CDS             25042..25359
                     /gene="metJ"
                     /locus_tag="IT892_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015855437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="met regulon transcriptional regulator MetJ"
                     /protein_id="HAP3134283.1"
                     /translation="MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRR
                     QVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPET
                     WEY"
     gene            25543..26151
                     /locus_tag="IT892_001045"
     CDS             25543..26151
                     /locus_tag="IT892_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX family permuted papain-like enzyme"
                     /protein_id="HAP3134284.1"
                     /translation="MKNRLLILSLLVSVPAFAWQPQTGDIIFQISRSSQSKAIQLATH
                     TDYSHTGMLVIRNKKPYVFEAVGPVKYTPLKQWIAHGEKGKYVVRRVEGGLSVEQQQK
                     LAQTAKRYLGKPYDFSFSWSDDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSSPQV
                     QAKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEWPLFSW"
     gene            complement(26212..26424)
                     /gene="rpmE"
                     /locus_tag="IT892_001046"
     CDS             complement(26212..26424)
                     /gene="rpmE"
                     /locus_tag="IT892_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HAP3134285.1"
                     /translation="MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFF
                     TGKQRDVATGGRVDRFNKRFNIPGSK"
     gene            26627..28825
                     /gene="priA"
                     /locus_tag="IT892_001047"
     CDS             26627..28825
                     /gene="priA"
                     /locus_tag="IT892_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAP3134286.1"
                     /translation="MPVAHVALPVPLPRTFDYLLPEGMTVKAGCRVRVPFGKQQERIG
                     IVVSVSDASELPLNELKAVVEVLDSEPVFTHSVWRLLLWAADYYHHPIGDVLFHALPI
                     LLRQGRPAANAPMWYWFATEQGQAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEF
                     NDAALQALRKKGLCDLASETPEFSDWRTNYAVSGERLRLNTEQATAIGAIHSAADTFS
                     AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVL
                     HSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVIDEEHDSSYKQQEGWR
                     YHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRLLRLTRRAGNARPAIQHVL
                     DLKGQKVQAGLAPALITRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDH
                     YYTLHQAQHHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTLAPLFPGVPIS
                     RIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA
                     DFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAE
                     RRMMQLPPWTSHVIVRAEDHNNQHAPLFLQQLRNLILSSPLADEKLWVLGPVPALAPK
                     RGGRWRWQILLQHPSRVRLQHIINGTLALINTIPDSRKVKWVLDVDPIEG"
     gene            28981..30006
                     /gene="cytR"
                     /locus_tag="IT892_001048"
     CDS             28981..30006
                     /gene="cytR"
                     /locus_tag="IT892_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CytR"
                     /protein_id="HAP3134287.1"
                     /translation="MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRV
                     EKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAANHGYLVLI
                     GDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
                     LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVD
                     PQYIARGDFTFEAGSKAMQQLLDLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLS
                     IIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHVGSGSRLMDCELIIR
                     GSTRALP"
     gene            30098..31057
                     /gene="ftsN"
                     /locus_tag="IT892_001049"
     CDS             30098..31057
                     /gene="ftsN"
                     /locus_tag="IT892_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HAP3134288.1"
                     /translation="MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVL
                     VTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEP
                     SAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
                     QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTT
                     AQSKPQQAAPVARAADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSK
                     ITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG"
     gene            31150..31680
                     /gene="hslV"
                     /locus_tag="IT892_001050"
     CDS             31150..31680
                     /gene="hslV"
                     /locus_tag="IT892_001050"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HAP3134289.1"
                     /translation="MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVI
                     AGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADET
                     ASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDIC
                     IYTNHFHTIEELSYKA"
     gene            31690..33021
                     /gene="hslU"
                     /locus_tag="IT892_001051"
     CDS             31690..33021
                     /gene="hslU"
                     /locus_tag="IT892_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase ATPase subunit"
                     /protein_id="HAP3134290.1"
                     /translation="MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEEL
                     RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
                     LTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFR
                     KKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKI
                     KDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREG
                     VQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQA
                     LTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGA
                     RRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL"
     gene            33088..34014
                     /gene="menA"
                     /locus_tag="IT892_001052"
     CDS             33088..34014
                     /gene="menA"
                     /locus_tag="IT892_001052"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAP3134291.1"
                     /translation="MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPL
                     VALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALIIT
                     VVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVLV
                     FFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLVV
                     RLGEVNARRYHACLLMGSLVCLALFNLFSLHSLWGWLFLLAAPLLVKQARYVMREMDP
                     VAMRPMLERTVKGALLTNLLFVLGIFLSQWAA"
     gene            34107..34592
                     /gene="rraA"
                     /locus_tag="IT892_001053"
     CDS             34107..34592
                     /gene="rraA"
                     /locus_tag="IT892_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HAP3134292.1"
                     /translation="MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFED
                     NGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDL
                     EELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
                     E"
     gene            complement(34677..34922)
                     /gene="zapB"
                     /locus_tag="IT892_001054"
     CDS             complement(34677..34922)
                     /gene="zapB"
                     /locus_tag="IT892_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring assembly protein ZapB"
                     /protein_id="HAP3134293.1"
                     /translation="MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQ
                     NAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV"
     gene            35347..36192
                     /gene="glpF"
                     /locus_tag="IT892_001055"
     CDS             35347..36192
                     /gene="glpF"
                     /locus_tag="IT892_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol uptake facilitator protein GlpF"
                     /protein_id="HAP3134294.1"
                     /translation="MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEI
                     SVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAA
                     LVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILM
                     GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAG
                     WGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRHLPCDICVVEEKETTTPSE
                     QKASL"
     gene            36215..37723
                     /gene="glpK"
                     /locus_tag="IT892_001056"
     CDS             36215..37723
                     /gene="glpK"
                     /locus_tag="IT892_001056"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAP3134295.1"
                     /translation="MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPG
                     WVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAI
                     VWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGE
                     LLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEV
                     RRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNT
                     GEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFA
                     TKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDV
                     LEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGL
                     AVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE"
     gene            37858..38868
                     /gene="glpX"
                     /locus_tag="IT892_001057"
     CDS             37858..38868
                     /gene="glpX"
                     /locus_tag="IT892_001057"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HAP3134296.1"
                     /translation="MRRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIML
                     NQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGRGDAVDIAVDPIEGTRMTAMGQANALA
                     VLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALGKPLSELTVT
                     ILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSA
                     AVIRALDGDMNGRLLARHDVKGDNEENRRIGEQELARCKAMGIEAGKVLRLGDMARSD
                     NVIFSATGITKGDLLEGISRKGNIATTETLLIRGKSRTIRRIQSIHYLDRKDPEMQVH
                     IL"
     gene            38965..39711
                     /gene="fpr"
                     /locus_tag="IT892_001058"
     CDS             38965..39711
                     /gene="fpr"
                     /locus_tag="IT892_001058"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP(+) reductase"
                     /protein_id="HAP3134297.1"
                     /translation="MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEID
                     GERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDE
                     VPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEK
                     RYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMV
                     RDTQQLLKETRQMTKHLRRRPGHMTAEHYW"
     gene            complement(39716..40144)
                     /gene="uspD"
                     /locus_tag="IT892_001059"
     CDS             complement(39716..40144)
                     /gene="uspD"
                     /locus_tag="IT892_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspD"
                     /protein_id="HAP3134298.1"
                     /translation="MAYKHIGVAISENEEDALLVNKALELARHNDAHLTLIHIDDGLS
                     ELYPGIYFPATEDILQLLKNKSDNKLYKLTKNIQWPKTKLRIERGEMPETLLEIMQKE
                     QCDLLVCGHHHSFINRLMPAYRGMINKMSADLLIVPFIDK"
     gene            complement(40171..40470)
                     /locus_tag="IT892_001060"
     CDS             complement(40171..40470)
                     /locus_tag="IT892_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF406 domain-containing protein"
                     /protein_id="HAP3134299.1"
                     /translation="MKDVVDKCSTKGCAIDIGTVIDNDNCTSKFSRFFATREEAESFM
                     TKLKELAAATSSADEGASVAYKIKDLEGQVELDAAFTFSCQAEMIIFELSLRSLA"
     gene            complement(40682..41122)
                     /locus_tag="IT892_001061"
     CDS             complement(40682..41122)
                     /locus_tag="IT892_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HAP3134300.1"
                     /translation="MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLVLFSLAGKNLLDI
                     QTAAFCLVCLLWPTAAVTVKRLHDRGRSGAWAFLMIVAWMLLAGNWAILPGVWQWAVG
                     RFVPTLILVMMLIDLGAFVGTQGENKYGKDTQDVKYKADNKSSN"
     gene            41223..41822
                     /locus_tag="IT892_001062"
     CDS             41223..41822
                     /locus_tag="IT892_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiQ family protein"
                     /protein_id="HAP3134301.1"
                     /translation="MKPGCTLFFLLCSALTVTTAAHAQTPDTATTAPYLLAGAPTFDL
                     SISQFREDFNSQNPSLPLNEFRAIDSSPDKANLTRAASKINENLYASTALERGTLKIK
                     SIQMTWLPIQGPEQKAAKAKAQEYMAAVIRTLTPLMTKTQSQKKLQSLLTAGKNKRYY
                     TETEGALRYVVADNGEKGLTFAVEPIKLALSESLEGLNK"
     gene            41930..42697
                     /gene="tpiA"
                     /locus_tag="IT892_001063"
     CDS             41930..42697
                     /gene="tpiA"
                     /locus_tag="IT892_001063"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAP3134302.1"
                     /translation="MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPE
                     MYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYH
                     KESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFE
                     GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNA
                     AELFAQPDIDGALVGGASLKAETFAVIVKAAEAAKQA"
     gene            complement(42752..43507)
                     /gene="cdh"
                     /locus_tag="IT892_001064"
     CDS             complement(42752..43507)
                     /gene="cdh"
                     /locus_tag="IT892_001064"
                     /EC_number="3.6.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
                     /protein_id="HAP3134303.1"
                     /translation="MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLP
                     NQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFW
                     LAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVRKQLDNNLAN
                     ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGRYGLAMVRQS
                     DNSFVLLATQRNLLTLNRASAEEIQDHQCEILR"
     gene            complement(43614..44603)
                     /locus_tag="IT892_001065"
     CDS             complement(43614..44603)
                     /locus_tag="IT892_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3134304.1"
                     /translation="MNKWGVGLTFLLAATSVMAKDIQLLNVSYDPTRELYEQYNKAFS
                     AHWKQQTGDNVVIRQSHGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKEWI
                     KRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAW
                     GYALHHNNNDQAKAQDFIRALYKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLA
                     ANELGKDKFEIVTPSESILAEPTVSVVDKVVEKKGTKEVAEAYLKYLYSPEGQEIAAK
                     NYYRPRDAEVAKKYENAFPKLKLFTIDEEFGGWTKAQKEHFANGGTFDQISKR"
     gene            complement(44923..45885)
                     /gene="pfkA"
                     /locus_tag="IT892_001066"
     CDS             complement(44923..45885)
                     /gene="pfkA"
                     /locus_tag="IT892_001066"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAP3134305.1"
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLG
                     LYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIG
                     GDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSS
                     HQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAI
                     VAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLL
                     LAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY"
     gene            complement(46066..46968)
                     /gene="fieF"
                     /locus_tag="IT892_001067"
     CDS             complement(46066..46968)
                     /gene="fieF"
                     /locus_tag="IT892_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312867.1"
                     /note="FieF, a metal efflux transporter, is a member of
                     the CDF (cation diffusion facilitator) family of
                     transporters; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family cation-efflux transporter FieF"
                     /protein_id="HAP3134306.1"
                     /translation="MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALV
                     DSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGI
                     QHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMM
                     NGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEI
                     IDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFP
                     GSDVIIHQDPCSVVPREGKRSMLS"
     gene            complement(47117..47617)
                     /gene="cpxP"
                     /locus_tag="IT892_001068"
     CDS             complement(47117..47617)
                     /gene="cpxP"
                     /locus_tag="IT892_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-envelope stress modulator CpxP"
                     /protein_id="HAP3134307.1"
                     /translation="MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSH
                     MFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKM
                     ANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
                     SNSRSQ"
     gene            47767..48465
                     /gene="cpxR"
                     /locus_tag="IT892_001069"
     CDS             47767..48465
                     /gene="cpxR"
                     /locus_tag="IT892_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response regulator transcription
                     factor CpxR"
                     /protein_id="HAP3134308.1"
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDS
                     IDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPF
                     NDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALVLNPGRQEASFDGQTLELTGT
                     EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWF
                     KTLRGRGYLMVSAS"
     gene            48462..49835
                     /gene="cpxA"
                     /locus_tag="IT892_001070"
     CDS             48462..49835
                     /gene="cpxA"
                     /locus_tag="IT892_001070"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress sensor histidine kinase CpxA"
                     /protein_id="HAP3134309.1"
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQR
                     QGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERSEM
                     QIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
                     FDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEF
                     LAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELER
                     IETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTV
                     NFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVS
                     PEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIW
                     LPLYKRS"
     gene            complement(49941..50615)
                     /gene="yiiM"
                     /locus_tag="IT892_001071"
     CDS             complement(49941..50615)
                     /gene="yiiM"
                     /locus_tag="IT892_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein"
                     /protein_id="HAP3134310.1"
                     /translation="MRYPVDVYTGKIQAYPEGKPSAIAKIQVDGELMLTELGLEGDEQ
                     AEKKVHGGPDRALCHYPREHYLYWAREFPEQAELFVAPAFGENLSTDGLTESNVYMGD
                     IFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGKVSADAPL
                     ELVSRVSDVTVQEAAAIAWHMPFDDDQYHRLLSAAGLSKSWTRTMQKRRLSGKIEDFS
                     RRLWGK"
     gene            complement(50764..51747)
                     /gene="kdgT"
                     /locus_tag="IT892_001072"
     CDS             complement(50764..51747)
                     /gene="kdgT"
                     /locus_tag="IT892_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate transporter"
                     /protein_id="HAP3134311.1"
                     /translation="MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMI
                     TGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVE
                     VGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGT
                     AGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTV
                     IAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEM
                     VPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK"
     gene            complement(52007..52627)
                     /gene="sodA"
                     /locus_tag="IT892_001073"
     CDS             complement(52007..52627)
                     /gene="sodA"
                     /locus_tag="IT892_001073"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Mn]"
                     /protein_id="HAP3134312.1"
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALE
                     SLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAA
                     IERDFGSVDNFKAEFEKAAASRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGAS
                     GFPIMGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     gene            52912..53946
                     /gene="rhaT"
                     /locus_tag="IT892_001074"
     CDS             52912..53946
                     /gene="rhaT"
                     /locus_tag="IT892_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
                     /protein_id="HAP3134313.1"
                     /translation="MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIV
                     SWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMG
                     IGIAIGITLIVGTLMTPIINGNFDVLISTEGGRMTLLGVLVALIGVGIVTRAGQLKER
                     KMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYV
                     VIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKSLIIHNVLLSTLGGLMWYLQFFFY
                     AWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVA
                     ANIVGIGMAN"
     gene            complement(53943..54881)
                     /gene="rhaR"
                     /locus_tag="IT892_001075"
     CDS             complement(53943..54881)
                     /gene="rhaR"
                     /locus_tag="IT892_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709710.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaR"
                     /protein_id="HAP3134314.1"
                     /translation="MAFCNNANLLNVFVRHIANNQLRSLAEVATVAHQLKLLKDDFFA
                     SDQQAVAVADRYPQDVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADD
                     KHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFNASAGQPHWRLGSMGMAQARQVI
                     GQLEHESSQHVPFANEMAELLFGQLVMLLNRHRYTSDSLPPTSSETLLDKLITRLAAS
                     LKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISD
                     ISTECGFEDSNYFSVVFTRETGMTPSQWRHLNSQKD"
     gene            complement(54865..55701)
                     /gene="rhaS"
                     /locus_tag="IT892_001076"
     CDS             complement(54865..55701)
                     /gene="rhaS"
                     /locus_tag="IT892_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaS"
                     /protein_id="HAP3134315.1"
                     /translation="MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHG
                     TGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLL
                     PQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKS
                     SLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQR
                     YLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGF
                     LQ"
     gene            55989..57458
                     /gene="rhaB"
                     /locus_tag="IT892_001077"
     CDS             55989..57458
                     /gene="rhaB"
                     /locus_tag="IT892_001077"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAP3134316.1"
                     /translation="MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHS
                     QNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAY
                     RDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLM
                     PDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIG
                     HWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTA
                     LAANITNEGGAEGRYRVLKNIMGLWLLQRVLQEQQINDLPALISATQALPACRFIINP
                     NDDRFINPETMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGE
                     DFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDF
                     RQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA"
     gene            57455..58714
                     /gene="rhaA"
                     /locus_tag="IT892_001078"
     CDS             57455..58714
                     /gene="rhaA"
                     /locus_tag="IT892_001078"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAP3134317.1"
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDD
                     VSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESD
                     TPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWID
                     HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNP
                     AHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAA
                     MLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINR
                     IAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYC
                     QRHDTPAGSEWLESVRAYEKEILSRRG"
     gene            58981..59805
                     /gene="rhaD"
                     /locus_tag="IT892_001079"
     CDS             58981..59805
                     /gene="rhaD"
                     /locus_tag="IT892_001079"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAP3134318.1"
                     /translation="MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAP
                     YHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGY
                     HILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAV
                     FTRQLWEGSTECLVVFPDGVGILPWMMPGTDEIGQATAQEMQKHSLVLWPFHGVFGSG
                     PTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL"
     gene            59815..60129
                     /gene="rhaM"
                     /locus_tag="IT892_001080"
     CDS             59815..60129
                     /gene="rhaM"
                     /locus_tag="IT892_001080"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAP3134319.1"
                     /translation="MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIY
                     LDKARNLLFAMVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFY
                     LP"
     gene            60430..60876
                     /locus_tag="IT892_001081"
     CDS             60430..60876
                     /locus_tag="IT892_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP3134320.1"
                     /translation="MAALTASCIDLNIQGNGAYSVLKQLATIALQNGFITDSHQFLQT
                     LLLREKMHSTGFGSGVAVPHGKSACVKQPFVLFARKAQAIDWKASDGEDVNCWICLGV
                     PQSGEEDQVKIIGTLCRKIIHKEFIHQLQQGDTDQVLALLNQTLSS"
     gene            60887..62338
                     /locus_tag="IT892_001082"
     CDS             60887..62338
                     /locus_tag="IT892_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIBC"
                     /protein_id="HAP3134321.1"
                     /translation="MESSLRIVAITNCPAGIAHTYMVAEALEQKARSLGHTIKVETQG
                     SSGVENRLSSEEIAAADYVILATGRGLSGDDRARFAGKKVYEIAISQALKNIDQIFSE
                     LPTNSQLFAADSGVKLGKQEVQSGSVMSHLIAGVSAALPFVIGGGILVALANMLVQFG
                     LPYTDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAFLVCYLAND
                     KALLGTQSGAGFLGAVVLGLAIGYFVFWFRKVRLGKALQPLLGSMLIPFVTLLVFGVL
                     TYYVIGPVMSDLMGGLLHFLNTIPPSMKFAAAFLVGAMLAFDMGGPINKTAWFFCFSL
                     LEKHIYDWYAIVGVVALMPPVAAGLATFIAPKLFTRQEKEAASSAIVVGATVATEPAI
                     PYALAAPLPMITANTLAGGITGVLVIAFGIKRLAPGLGIFDPLIGLMSPVGSFYLVLA
                     IGLALNISFIIVLKGLWLRRKAKAAQQELVHEH"
     gene            62328..63398
                     /locus_tag="IT892_001083"
     CDS             62328..63398
                     /locus_tag="IT892_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP3134322.1"
                     /translation="MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGS
                     FVARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRFTTIGGWWNQSMLNHRVTIRTHK
                     GVKIPGVIGSVAPHALTEKQKQQPLSFDEMFIDIGANSREEVEKRGVEIGNFISPEAN
                     FACWGEDKVVGKALDNRIGCAMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEH
                     IKPDVVIVLDTAVAGDVPGIDNIKYPLKLGQGPGLMLFDKRYFPNQKLVAVLKSCAAH
                     NDLPLQFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSGMISKADYEALLTLI
                     RGFLTTLTAEKVNAFSQFRQVD"
     gene            63398..65146
                     /locus_tag="IT892_001084"
     CDS             63398..65146
                     /locus_tag="IT892_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP3134323.1"
                     /translation="MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFT
                     LNGKARIFASGSAGYQLEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALN
                     LPETWVAERLPRLKQRYERTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLA
                     GITRDNLQHLSTACDNQHRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIV
                     EHSGLFLGDNAVRTLTGLIEKQHQQAQVISADNVQGLLQRVPGIASLNIIDAQLVENI
                     TGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLREQLDIPLFDSDLIG
                     LYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLNCRVIIARSLSELVAIREE
                     IEPLLIINNSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGS
                     FHYSNVRGESWQHITRQICAQLVAQHHITADEAQRIIAREGEGENLIVNRLAIPHCWS
                     EQERRFRGFFITLAQPVEVNNEVINHVLIACAAADARHELKIFSYLASILCQHPAEII
                     AGLTGYEAFMELLHKG"
     gene            complement(65196..66251)
                     /locus_tag="IT892_001085"
     CDS             complement(65196..66251)
                     /locus_tag="IT892_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiG family protein"
                     /protein_id="HAP3134324.1"
                     /translation="MKRNLLSSAIIVAIMSLGLTGCDDKKAETETLPPANSQPAAPAP
                     EAKPTEAPVAKAEAKPETPAQPVVDEQAVFDEKMDVYIKCYNKLQIPVQRSLARYADW
                     LKDFKQGPTGEERTVYGIYGISESNLAECEKGVKSAVALTPALQPIDGVAVSYIDAAV
                     ALGNTINEMDKYYTQENYKDDAFAKGKTLHQTFLKNLEAFEPVAESYHAAIQEINDKR
                     QLAELKNIEEREGKTFHYYSLAVMISAKQINNLISQDKFDAEAAMKKVSELETLVAQA
                     KEADKGGMNFSFINSAGQYQLEAKKYVRRIRDKVPYSDWDKEQLQDANSSWMVEDSFP
                     RALREYNEMVDDYNSLR"
BASE COUNT        16106 a        17671 c        17059 g        15469 t
ORIGIN      
        1 taaggcgctc gcgccgcatc cggcactgtt gccaaactcc agtgccgcaa taatgtcgga
       61 tgcgatactt gcgcatctta tccgacctac acctttggtg ttacttgggg cgatttttta
      121 acatttccat aagttacgct tatttaaagc gtcgtgaatt taatgacgta aattcctgct
      181 atttattcgt ttgctgaagc gatttcgcag catttgacgt caccgctttt acgtggcttt
      241 ataaaagacg acgaaaagca aagcccgagc atattcgcgc caatgcgacg tgaaggatac
      301 agggctatca aacgataaga tggggtgtct ggggtaatat gaacgaacaa tattccgcat
      361 tgcgtagtaa tgtcagtatg ctcggcaaag tgctgggaga aaccatcaag gatgcgttgg
      421 gagaacacat tcttgaacgc gtagaaacta tccgtaagtt gtcgaaatct tcacgcgctg
      481 gcaatgatgc taaccgccag gagttgctca ccaccttaca aaatttgtcg aacgacgagc
      541 tgctgcccgt tgcgcgtgcg tttagtcagt tcctgaacct ggccaacacc gccgagcaat
      601 accacagcat ttcgccgaaa ggcgaagctg ccagcaaccc ggaagtgatc gcccgcaccc
      661 tgcgtaaact gaaaaaccag ccggaactga gcgaagacac catcaaaaaa gcagtggaat
      721 cgctgtcgct ggaactggtc ctcacggctc acccaaccga aattacccgt cgtacactga
      781 tccacaaaat ggtggaagtg aacgcctgtt taaaacagct cgataacaaa gatatcgctg
      841 actacgaaca caaccagctg atgcgtcgcc tgcgccagtt gatcgcccag tcatggcata
      901 ccgatgaaat ccgtaagctg cgtccaagcc cggtagatga agccaaatgg ggctttgccg
      961 tagtggaaaa cagcctgtgg caaggcgtac caaattacct gcgcgaactg aacgaacaac
     1021 tggaagagaa cctcggctac aaactgcccg tcgaatttgt tccggtccgt tttacttcgt
     1081 ggatgggcgg cgaccgcgac ggcaacccga acgtcactgc cgatatcacc cgccacgtcc
     1141 tgctactcag ccgctggaaa gccaccgatt tgttcctgaa agatattcag gtgctggttt
     1201 ctgaactgtc gatggttgaa gcgacccctg aactgctggc gctggttggc gaagaaggtg
     1261 ccgcagaacc gtatcgctat ctgatgaaaa acctgcgttc tcgcctgatg gcgacacagg
     1321 catggctgga agcgcgcctg aaaggcgaag aactgccaaa accagaaggc ctgctgacac
     1381 aaaacgaaga actgtgggaa ccgctctacg cttgctacca gtcacttcag gcgtgtggca
     1441 tgggtattat cgccaacggc gatctgctcg acaccctgcg ccgcgtgaaa tgtttcggcg
     1501 taccgctggt ccgtattgat atccgtcagg agagcacgcg tcataccgaa gcgctgggcg
     1561 agctgacccg ctacctcggt atcggcgact acgaaagctg gtcagaggcc gacaaacagg
     1621 cgttcctgat ccgcgaactg aactccaaac gtccgcttct gccgcgcaac tggcaaccaa
     1681 gcgccgaaac gcgcgaagtg ctcgatacct gccaggtgat tgccgaagca ccgcaaggct
     1741 ccattgccgc ctacgtgatc tcgatggcga aaacgccgtc cgacgtactg gctgtccacc
     1801 tgctgctgaa agaagcgggt atcgggtttg cgatgccggt tgctccgctg tttgaaaccc
     1861 tcgatgatct gaacaacgcc aacgatgtca tgacccagct gctcaatatt gactggtatc
     1921 gtggcctgat tcagggcaaa cagatggtga tgattggcta ttccgactca gcaaaagatg
     1981 cgggagtgat ggcagcttcc tgggcgcaat atcaggcaca ggatgcatta atcaaaacct
     2041 gcgaaaaagc gggtattgag ctgacgttgt tccacggtcg cggcggttcc attggtcgcg
     2101 gcggcgcacc tgctcatgcg gcgctgctgt cacaaccgcc aggaagcctg aaaggcggcc
     2161 tgcgcgtaac cgaacagggc gagatgatcc gctttaaata tggtctgcca gaaatcaccg
     2221 tcagcagcct gtcgctttat accggggcga ttctggaagc caacctgctg ccaccgccgg
     2281 agccgaaaga gagctggcgt cgcattatgg atgaactgtc agtcatctcc tgcgatgtct
     2341 accgcggcta cgtacgtgaa aacaaagatt ttgtgcctta cttccgctcc gctacgccgg
     2401 aacaagaact gggcaaactg ccgttgggtt cacgtccggc gaaacgtcgc ccaaccggcg
     2461 gcgtcgagtc actacgcgcc attccgtgga tcttcgcctg gacgcaaaac cgtctgatgc
     2521 tccccgcctg gctgggtgca ggtacggcgc tgcaaaaagt ggtcgaagac ggcaaacaga
     2581 gcgagctgga ggctatgtgc cgcgattggc cattcttctc gacgcgtctc ggcatgctgg
     2641 agatggtctt cgccaaagca gacctgtggc tggcggaata ctatgaccaa cgcctggtag
     2701 acaaagcact gtggccgtta ggtaaagagt tacgcaacct gcaagaagaa gacatcaaag
     2761 tggtgctggc gattgccaac gattcccatc tgatggccga tctgccgtgg attgcagagt
     2821 ctattcagct acggaatatt tacaccgacc cgctgaacgt attgcaggcc gagttgctgc
     2881 accgctcccg ccaggcagaa aaagaaggcc aggaaccgga tcctcgcgtc gaacaagcgt
     2941 taatggtcac tattgccggg attgcggcag gtatgcgtaa taccggctaa tcttcctctt
     3001 ctgcaaaccc tcgtgctttt gcgcgagggt tttctgaaat acttctgttc taacaccctc
     3061 gttttcaata tatttctgtc tgcattttat tcaaattctg aatatacctt cagatatcct
     3121 taaggaattg tcgttacatt cggcgatatt ttttcaagac aggttcttac tatgcattcc
     3181 acagaagtcc aggctaaacc tctttttagc tggaaagccc tgggttgggc actgctctac
     3241 ttttggtttt tctctactct gctacaggcc attatttaca tcagtggtta tagtggcact
     3301 aacggcattc gcgactcgct gttattcagt tcgctgtggt tgatcccggt attcctcttt
     3361 ccgaagcgga ttaaaattat tgccgcagta atcggcgtgg tgctatgggc ggcctctctg
     3421 gcggcgctgt gctactacgt catctacggt caggagttct cgcagagcgt tctgtttgtg
     3481 atgttcgaaa ccaacaccaa cgaagccagc gagtatttaa gccagtattt cagcctgaaa
     3541 attgtgctta tcgcgctggc ctatacggcg gtggcagttc tgctgtggac acgcctgcgc
     3601 ccggtctata ttccaaagcc gtggcgttat gttgtctctt ttgccctgct ttatggcttg
     3661 attctgcatc cgatcgccat gaatacgttt atcaaaaaca agccgtttga gaaaacgttg
     3721 gataacctgg cctcgcgtat ggagcctgcc gcaccgtggc aattcctgac cggctattat
     3781 cagtatcgtc agcaactaaa ctcgctaaca aagttactga atgaaaataa tgccttgccg
     3841 ccactggcta atttcaaaga tgaatcgggt aacgaaccgc gcactttagt gctggtgatt
     3901 ggcgagtcga cccagcgcgg acgcatgagt ctgtacggtt atccgcgtga aaccacgccg
     3961 gagctggatg cgctgcataa aaccgatccg aatctgaccg tgtttaataa cgtagttacg
     4021 tctcgtccgt acaccattga aatcctgcaa caggcgctga cctttgccaa tgaaaagaac
     4081 ccggatctgt atctgacgca gccgtcgctg atgaacatga tgaaacaggc gggttataaa
     4141 accttctgga tcaccaacca gcagacgatg accgcccgca ataccatgct gacggtattt
     4201 tcgcgccaga ccgacaagca gtactacatg aaccagcaac gtacgcagag tgcgcgtgaa
     4261 tacgacacca acgtgctgaa gccgttccag gaagtgctga atgaccctgc gccgaagaaa
     4321 ctgatcattg ttcatctgct gggtacgcat atcaaataca aataccgcta cccggaaaat
     4381 cagggcaagt ttgatggcaa taccgatcat gttccgccgg gattaaacgc ggaagagctg
     4441 gagtcatata acgattatga caacgctaac ctgtataacg atcatgtggt tgccagcctg
     4501 attaaagact ttaaagcagc aaacccgaac ggtttcctgg tttatttctc tgaccacggt
     4561 gaagaggttt acgacacgcc gccgcacaaa actcaggggc gtaatgagga caacccgacg
     4621 cgtcatatgt acaccattcc gttcctgctg tggacgtcag aaaaatggca agcgactcat
     4681 ccccgtgatt tctcgcagga tgttgatcgt aaatacagcc tggcggaact gatccacacc
     4741 tggtcagatt tggcgggctt atcttacgac ggttacgatc caacccgttc agtggtgaat
     4801 ccgcagttca aagaaactac ccgctggatt ggtaacccgt ataagaaaaa cgcactgatc
     4861 gattacgaca cactgcccta tggcgatcag gtgggtaatc agtaattatc agccaggcgc
     4921 tatttgccgg atgcgacgct tgacgcgtct tatccggcct acagatcgcg gcggtaggct
     4981 ggataaggcg tttacgccac atccggcaat acaactgccg caatgtttac atcgaactcc
     5041 cctcaggcca cacttttcag gtggcctttt ttaataatgc cagttactgt tttcccgtct
     5101 acatacctaa gggaataaca tgtatcacga cgtcagctat ctgctctccc gcctgatcaa
     5161 cggcccgctg tccctgcgcc agatttactt tgccagcagt aacggctcgg tgcccgatct
     5221 tgcgtatcag gtcgattttc cacggctgga aattgtgctg gaaggtgagt ttgttgatac
     5281 cggcgctgga gcaacgttag ttcccggcga tgtgctgtac gttcctgctg gtggctggaa
     5341 ttttccacaa tggcaagccc ccgctactac ctttagcgtg ctgtttggca aacagcaact
     5401 cggcttcagc gtcgtgcaat gggatggcaa acaatatcaa aatctggcga agcaacacgt
     5461 cgcccgacgc ggcccacgca taggttcttt tctgctacaa acgctcaatg aaatgcaaat
     5521 gcagccgcag gagcagcaaa cggcaaggct tatcgtcgcc agcctgctta gccactgccg
     5581 cgatttgctt ggcagccaaa tccagaccgc ctcacgcagc caggcactat ttgaagctat
     5641 tcgcgattat atcgacgaac gctatgcctc cgcgcttacc cgcgaatctg ttgcacaggc
     5701 gttttatatt tcgccaaatt acctctcgca cctgtttcaa aaaacggggg ccattggttt
     5761 taacgaatac ctgaatcaca cgcgactgga gcacgctaag acgttattga aaggctatga
     5821 cctgaaggta aaagaagtgg cgcacgcctg cggctttgtc gacagcaact acttctgccg
     5881 tctgtttcgt aaaaacaccg aacgctcgcc gtcggaatat cgccggcagt accacagcca
     5941 actgacagaa aaaccgacta ctccagaata agatgggttt gctgcggcgc agaaagcact
     6001 ttgcgcaccg cgctcattac ccgctgcggc tcacgcagga atgcgtagat gctgcattgc
     6061 acatagcggc aatgttcaaa ttgctcggca ccggcaagct cgatatccgt aatcaacaga
     6121 gcaacatccg cccggcggat atcctcatcc gctaaacgat tctccgttcc cagcgcgccc
     6181 tgagtttcaa tgctgactcc ccacttctct aacaggcaca acttttccag ccgttccgcc
     6241 gccatataag tatgcgccac gccgcttacg caggcggtta ctgccaccag gtatgccatt
     6301 ttaacctccc acggtaacct gaagtccggc ccgttctgcc atttcgcgca tcgttgccac
     6361 atcagctgac gacggcgcag gcacctcttt catcgaccat gttttcccca gcaggcggta
     6421 tttcggttcg ccgtactgat gaaacggtaa cagatggatc tgcctgatat tcagcgggat
     6481 cagtacatcc agcgcctgct gcatattctc ccggctgagc gtgaaaccag ggatcagcgg
     6541 taaacgcggg atcacgttga cgccctcact caccagcaaa cgcagattct ccagcacgcg
     6601 tggcaggttc atcttcacca catcccgcgc ctgagtcgcg tccataattt ttaaatcgaa
     6661 caacacttca tcgcacaatt tcgccagcgg taatagcttg ctggctggtg cgtctccggc
     6721 agtttcaatg gcgcatgaca caccccacag ccgcagtcgc tgtaaaaaac gggtagcaaa
     6781 ctccgcctgc attaacactt cgccgccaga aagcgtgacg ccgccgccgg acgtgcgaaa
     6841 gaaaatgtca tctttcatca cttcccgttc cagagcgtca aggctgatat cgcgaccaat
     6901 ccgttcaaac gccccggagg ggcattcatc cgcatcacgc aaacatttcg cacagtgcag
     6961 acatttcgcc tctctgcgta ccgtctggat tttgccggag atcgactccg gattagcaca
     7021 ccacgggcaa agatgcggac agcctttaaa aaagaccacc gtacgaatgc cctcgccgtc
     7081 attcagtgaa taacgctgaa tgttgaaaat gcgcgccaca tcatcgcggc gcgtttccac
     7141 aacgttacag ctgatgcgct gtccggcgga tgatgtcatc ctggatctcc ttcgacagtt
     7201 cgacaaagaa ggcgctgtat ccggcaacgc gcaccaccag cccggcataa tcttgtgggc
     7261 gctgttgcgc ttcccgcaac gtgtcggcgt tcaccacgtt aaactgaata tgttgtaact
     7321 taagctgggt aaacgcccgt aagaagtcgg ccagtttgcg taatcctgct tcaccttcca
     7381 gggtcgccgg agtgaatttc acgttcagca acgtaccgtt agacagcagc gtgttatcga
     7441 gcttactgac tgacttcagt accgctgttg gcccttgtgc gtcctggccc agcatgggtg
     7501 acaagccgcc gtctgccagc tgttctccgg caaaacgacc gtctggcgtc gcgccaacca
     7561 ccgatcccaa cgggacgtga gcagaaacgg tatacgatcc cggcgtgaag tagccgccgc
     7621 gcgggttctg gtatttttcc acttctttgc agtagtggcg caacagttcg gcgctgatgt
     7681 tatccacctc gtcgatatcg ttaccgtatt tctcgaagcg gttaattaag cgagcgcgga
     7741 ctttttcgcc ttctggcgtt gcgaagttgg cttttaatac cgacagcaat tcgtcaaaac
     7801 ttaaacgctg ttgctcaaaa accatccctt tcaacgcatg gagagaatcg ctcaggttgg
     7861 cgataccgat cccctgtacg ccggagaagt tataacgcgc gccgccatcg gtaatatcgc
     7921 ggcctttttc cagacaatcg ctgataaacg atgagagcag cggtacaggt gcccagtcgc
     7981 gatggccgat atcacaaata ttgctgccct caaccatcag ggtgatgtag tggctgatct
     8041 tggcgcggat ctgctcgagt aaaccttcat aagtcagcgc agcattgcct tcattttcat
     8101 gcaggcagat ttccatcact ttcagcagat taaacatcgc gatgtcatgc aagccgtagg
     8161 ttctgccggg aatagataat tccacacagc ccactacgga atagtcgcgc gcatcttcca
     8221 gcgaaacgcc acggttgagg aacgctggca ccaccacttc atcgttaaag atttgcggaa
     8281 taccggtgcc gaagcgaatg gtttcggcgg ttttcatcag gaacggcgtg tcgatcaagg
     8341 cgttagtgcg cacgccgagg ttcggttgcg gtaattgcac gctttgatag gcgtcaaggc
     8401 aaaggaacga aagcacgttc accgcgctac gtccgttctc ggttaacccg ccgagcagtg
     8461 cggtatagcc ggtcgggaaa ccggcgaaat aacgcgcgct actggtggag cgtaacagca
     8521 cgatgtcgtt gcatttcacc cataaagatt cgagcagttc tttcaggaac gccgcatctt
     8581 cgccctgggt taatgatgtc tgatagaacg gcaacatata ctggtcgaag cgccccaacg
     8641 atagcgaact ggcgttggat tcgtattgca gaatgatgtt catgtaccag aataactggc
     8701 acgcctgcca gaacgtctgc ggcttatgtt gcgcgttatg gcgggagatc tctgcaatag
     8761 tcagcagctc ttcgcgacgc tgggcatctg tgcagtttgc cgccatcgtt tccgccagtt
     8821 cggcgtaacg caaaatgtgt ttctgcgagg cttccagcag taacaacgcg gcctgataaa
     8881 agtgattctc cggctgttgc tgacaatgtt gctgcatctg tgccaccagc tcacccagcc
     8941 cgtgattcaa caggcgtggg taatcaataa taatgtgccc ctggccttta tccgtctggt
     9001 tgatgctgaa aatctgcgtg ttggtcgcgg cttttacttc atctgtcatc tgcccgttga
     9061 tgaaatcttt catcgaacgt ttttcccagt acgggaacaa ctcttcacgg tagatacgtt
     9121 tatcttcttc gctgatagca aagcggtcct gcggacgcgt cgggaattga tccagctctt
     9181 tcagcagcca gtaagggtcc atttccggcg acataatccc ggcgcgcggt tttacggtgc
     9241 ggttaccggc aatcagttct tcatcacgaa tcgaaatttc aacatgttca aggatatacg
     9301 ctgttgcttt cgcccggcgc aatatcaccg gttcgccttc ggtttgccga tggctggcgg
     9361 tataaagcag cgcccgctcc agcgagattt cacgggtatt ggcaaacagt gcagttttga
     9421 ggcgagagat acgattcgtc atgaggaact cctgtgggaa agcgaacccg cccttgcgag
     9481 cgggagaaga acttaagcgg tttgcgccag gtgagcttca attttgctca taatggcgtc
     9541 agcacgtttt actgcatcgc tgatgttgac gcgcacgatg gtcttgccag caaaacgctc
     9601 ttcaaacttg atgccgatat ctttggtcag aatcaccata tcagcgctcg ccacatcttc
     9661 cgcagtcagt tcattttcca gaccaattga cccctgggtt tctactttca cttcccagcc
     9721 tttcgctttc gcggcacttt ccagcgcctc tgctgccata taggtatggg caacacctga
     9781 aggacatgcg gttactgcaa taattttcgt catggctcgt tcctcaatta attaatttca
     9841 aaatccaaat ccaggtcgtc ttctttttca tcagtcgaag acccattttt acgcgccaga
     9901 cttttcagca cgttcacaca aacagccgtc accactgctc cgacagccac tgctgcgata
     9961 taacccagct tgccttcaac caccggcagc acaatcagac caccccagcc tgcatagcac
    10021 tgcgcaccga ccagcgccgc agttactgca ccacaaactg aaccgaccat gatggaagga
    10081 atgacacgca gcggatcggc agcggcgaaa ggaatcgccc cttcagtaac gccaacacag
    10141 cccatcacca gtgccgcttt gccggtttcg cgctcttctg cggagaaatt tttacgacca
    10201 atcagcgtcg ccagccccat ccccagcggc gggatacaaa tacccacggc agcgatggcc
    10261 accacggtat aaacaccctg agcaacgcaa atcagcatga aggcataggc cactttgtta
    10321 accggaccgc ccatatcgaa cgccagcatc agacccatga tcaccgccag cataacaatg
    10381 ctgccctgct gcatcccctg aagccactga gtcaggctgt tggtcaacgc ccctacaggc
    10441 tcgcccaagc cccacatcat gatgcctgcg gtaatcagtg tgccgacgat aggaataatg
    10501 aagataggca tcaccgagcg cagaacttta tgcaccggaa ttttcttcag gtaatgcacc
    10561 acgatgccgc cgataatccc ggcgatcagt gcaccaaaga agcccgcacc aaagctgtta
    10621 ccaacccagg caccgatagc gcacggagcc agcgcagaac gctctgcaat ggaataaccg
    10681 atgtacgctg cgaggaaagg caccatcagc gtcaagcccg caacgccgat atcaaacagt
    10741 tttttcagat ttggatcggc tacggcatcc ggcactgcgc ctttgccata caacatgacg
    10801 gaaaccgcca gcaaaatacc gcccgatacc acgaagggaa tcatgtgtga aacgcccgtc
    10861 attaaatgct gacgggtatt tttcaggatc tgcaccaact cattcataag ctgctcccgg
    10921 gcttgcgaaa gcccatgtcc atatttttga tggaggaaac aataggcaat cgcaggcgga
    10981 gcaaacagtg gataaaaagg ccatttactg gacttttgta atatcagtac aaaaatgcga
    11041 tccgcctcat aacttgcgat aaaccggaag catgccgcaa aacagcgtct tgtgagacgc
    11101 gtcgcaaatt gacggttaca ttacatttat ccagcttttg gcagatttgt cacatggcag
    11161 gccgttgccg tgcgctctta tcctgtaaac agaaaaccgt accgggagag aggcaatggc
    11221 cctgattgtg gaatttattt gtgagttacc taacggcgta catgcgcgtc cggcaagcca
    11281 cgttgaaacg ctgtgtaata ctttttcatc acaaattgag tggcataacc tgcgcactga
    11341 ccgcaagggc aacgccaaaa gcgcccttgc gctgattggc accgatacgc tggcgggcga
    11401 taactgccag ttactgattt ccggggccga cgaacaggaa gcgcaccagc gtttaagcca
    11461 atggctgcgc gatgaattcc cccactgcga tgcgccgctg gcggaagtta aatctgacga
    11521 actggaacca ctgccggttt cactgaccaa tctgaatccg caaattatcc gcgcccgcac
    11581 cgtgtgcagc ggtagtgcag gcggcattct gacgccgatc tcttctttag atctcaatgc
    11641 gctgggtaat cttcccgcag ccaaaggcgt tgacgccgag caatccgcac tggaaaacgg
    11701 cctgacgctg gtactgaaaa acattgagtt tcgtctgctg gatagcgacg gtgctaccag
    11761 cgcgattctg gaagctcacc gatccctggc tggcgatact tccctgcgcg aacatttact
    11821 ggcaggcgtc agcgccggat taagctgcgc cgaagcaatt gttgccagcg cgaatcactt
    11881 ttgcgaagag ttttcccgtt ccagcagcag ctacctgcaa gaacgtgccc tggacgtacg
    11941 cgacgtctgc ttccagttac tccagcaaat ctacggtgag caacgcttcc cggcaccggg
    12001 caaactgacg cagcccgcca tttgtatggc tgatgaactg acccccagcc agttcctcga
    12061 actggataaa aatcacctca aaggattgtt gctcaaaagc ggcggcacca cctcacatac
    12121 ggtgatcctt gcccgttcgt tcaacattcc aacgctggtt ggtgtggata ttgatgccct
    12181 tactccgtgg cagcaacaaa cgatttatat cgacggcaac gccggggcga ttgtggttga
    12241 gccaggggaa gccgtagctc gttattatca gcaagaagcc cgcgtacagg acgccctgcg
    12301 tgagcaacag cgtgtctggc tgacccaaca agcccgtacc gctgacggta tccgcattga
    12361 aattgccgct aacatcgctc actccgtgga agcgcaggcc gcattcggca atggtgcgga
    12421 aggcgttggt ttgttccgca ctgaaatgct ctatatggat cgcaccagcg caccgggcga
    12481 aagcgagttg tacaacattt tttgtcaggc gctggaatcc gccaacggac gcagcattat
    12541 tgtgcgcact atggacattg gcggcgacaa acccgttgat tatctgaaca ttcccgcaga
    12601 ggcaaacccg ttcctcggtt atcgcgccgt gcgtatttat gaagagtacg cgtcgttgtt
    12661 taccacgcag ctacggtcga tcctccgcgc ctccgctcac ggcagcctga aaatcatgat
    12721 cccgatgatc tcctcaatgg aagagatctt atgggtgaaa gaaaaactgg cggaagccaa
    12781 acagcaacta cgtaacgaac acattccgtt tgatgagaaa atccagctcg gcatcatgct
    12841 ggaagtgccg tcggtgatgt tcatcatcgg tcaatgctgc gaagagattg atttctttag
    12901 tattggtagt aatgacctga cgcagtatct gctggcggtg gatcgcgata acgctaaggt
    12961 tactcgtcac tacaacagcc tgaatccggc attcttgcgg gcgctcgatt acgccgtgca
    13021 agcggtgcat cgccagggca aatggattgg tctgtgcggt gagctgggag cgaaaggttc
    13081 cgtgctgccg ttgctggtcg gcttagggct ggatgaactc agcatgagcg caccatcaat
    13141 tccggcggcg aaagctcgga tggcgcaact tgatagccgt gagtgccgca agttgctcaa
    13201 ccaggcaatg gcctgccgta cttcgctgga agtggaacac ctgctggcgc aattccgcat
    13261 gacccaacaa gacgcaccgc tggtcaccgc cgagtgcatc acactggaaa gcgactggcg
    13321 cagcaaagaa gaagtgctca aaggcatgac cgataacctg ctgctggcgg gccgctgccg
    13381 ctatccgcgt aaactggaag ccgacttgtg ggcgcgcgag gccgttttct ctaccggtct
    13441 gggctttagt tttgccattc cacacagcaa atcagaacac attgagcaat ccaccatcag
    13501 cgtggcgcgt ctgcaagcgc cggtgcgctg gggcgatgat gaagcgcaat tcatcattat
    13561 gttaaccctg aacaaacacg ctgcgggcga tcagcatatg cgcattttct cgcgcctcgc
    13621 tcgccgcatc atgcacgaag aattccgtaa cgcgctggtt aacgccgcct ctgccgacgc
    13681 tatcgccagc ctgctgcaac atgaactgga actgtaaaag gaaacatcat ggaactgtat
    13741 ctggacaccg ctaacgtcgc agaagtcgaa cgtctggcac gcatattccc cattgccggg
    13801 gtgacaacta acccgagcat tatcgctgcc agcaaggagt ccatatggga agtgctgccg
    13861 cgtctgcaaa aagcgattgg tgatgagggc attctgtttg ctcagaccat gagccgcgac
    13921 gcgcagggga tggtggaaga agcgaagcgc ctgcgcgacg ctattccggg tattgtggtg
    13981 aaaatcccgg tgacttccga aggtctggca gcaattaaaa tactgaaaaa agagggtatt
    14041 actacacttg gcactgctgt atatagcgcc gcacaagggt tattagccgc actggcaggg
    14101 gcaaaatacg ttgctccgta tgttaaccgc gtagatgccc agggcggaga cggcattcgt
    14161 acggttcagg agctgcaaac gctgttagaa atgcacgcgc cagaaagcat ggtgctggca
    14221 gccagcttta aaacgccgcg tcaggcgctg gactgtttac tggcaggatg tgaatccatc
    14281 accctgccct tagatgtagc gcaacaaatg ctcaacaccc ctgcggtaga gtcagctata
    14341 gagaagttcg aacacgactg gaatgccgca tttggcacta ctcatctcta aaggagcaat
    14401 tatggaccgc attattcaat caccgggtaa atacatccag ggcgctgatg tgattaatcg
    14461 tctgggcgaa tacctgaagc cgctggcaga acgctggtta gtggtgggtg acaaatttgt
    14521 tttaggtttt gctcaatcca ctgtcgagaa aagctttaaa gatgctggac tggtagtaga
    14581 aattgcgccg tttggcggtg aatgttcgca aaatgagatc gaccgtctgc gtggcatcgc
    14641 ggagactgcg cagtgtggcg caattctcgg tatcggtggc ggaaaaaccc tcgatactgc
    14701 caaagcactg gcacatttca tgggtgttcc ggtagcgatc gcaccgacta tcgcctctac
    14761 cgatgcaccg tgcagcgcat tgtctgttat ctacaccgat gagggtgagt ttgaccgcta
    14821 tctgctgttg ccaaataacc cgaatatggt cattgtcgac accaaaatcg tcgctggcgc
    14881 acctgcacgt ctgttagcgg cgggtatcgg cgatgcgctg gcaacctggt ttgaagcgcg
    14941 tgcctgctct cgtagcggcg cgaccaccat ggcgggcggc aagtgcaccc aggctgcgct
    15001 ggcactggct gaactgtgct acaacaccct gctggaagaa ggcgaaaaag cgatgcttgc
    15061 tgccgaacag catgtagtga ctccggcgct ggagcgcgtg attgaagcga acacctattt
    15121 gagcggtgtt ggttttgaaa gtggtggtct ggctgcggcg cacgcagtgc ataacggcct
    15181 gaccgctatc ccggacgcgc atcactatta tcacggtgaa aaagtggcat tcggtacgct
    15241 gacgcagctg gttctggaaa atgcgccggt ggaggaaatc gaaaccgtag ctgcccttag
    15301 ccatgcggta ggtttgccaa taactctcgc tcaactggat attaaagaag atgtcccggc
    15361 gaaaatgcga attgtggcag aagcggcatg tgcagaaggt gaaaccattc acaacatgcc
    15421 tggcggcgcg acgccagatc aggtttacgc cgctctgctg gtagccgacc agtacggtca
    15481 gcgtttcctg caagagtggg aataacctac tccaaactcc cggcttgtcc gggagtttga
    15541 acgcaaaatt gcctgatgcg ctacgcttat caggcctacg caatctctgc aatatattga
    15601 atttgcgtgc ttttgtaggc cggataaggc gttcactccg catccggcac tctgtgccag
    15661 taatctgaaa ctcccacgtt gttcaggaat tttttatccg cttctggaca ttttctctac
    15721 agaacaatcg ttagcccgga aggtcgaatc tgtgactctt attttcacgg acgaaccaga
    15781 tgaaagcttc actggcgctg ctcagcctgc taacggcatt taccagccac tccttaaaat
    15841 ctcccgccgt tccaccaacc gtggtacaaa tccaggccaa taccaacctt gccatcgcag
    15901 acggtgccag acagcaaatt ggcagcacgc tattttacga tccggcgtat gtgcagctta
    15961 cttatcctgg cggtgatgtt ccgcaagaac gcggtgtatg ttccgatgtg gtgatccgcg
    16021 cattgcgcag ccagaaggtc gatttgcaga aactggttca cgaagatatg gcgaagaatt
    16081 ttgctgagta cccgcaaaaa tggaagttaa agcgctcgga cagcaacatc gatcaccgtc
    16141 gggtgcctaa tctggaaacc tggtttagcc gccatgataa aacacgcccc accagcaaga
    16201 accccagtga ctatcaagcg ggcgatattg tctcctggcg actggataac gggctggcac
    16261 atattggggt ggtttcagat ggcttcgccc gcgacggtac gccgctggtg atacataaca
    16321 ttggcgcagg cgcgcaggaa gaagatgtgc tgtttaactg gcggatggtg gggcattatc
    16381 gttattttgt taaataagag atcgccccac atgaagaaaa aattcagatc ctttttacac
    16441 tgacggcttc ttttttctta cggctcacca gcgccagtgc cagcacaatc agcacaatac
    16501 cgctaccttc aacggccccc ggattctcgc cgagcagcca ccaggaaaag agtacgccgc
    16561 aaacgggaac ggccagtgtg cttaagctgg caatactggc aggcaagttt ttcaatacaa
    16621 acaaccataa gctccacgcc agtgccgtcg ccagaatcgc actgtaggcc agcgcccaga
    16681 acacggtggg ctgccagtca atttcacgtt gcggcaccag taaagcgacc acactcatca
    16741 ccagcgccgc atacagcatc tgccaggatg ttaacgacaa taaatccacg cgcggatgac
    16801 gggcatacag acgtttagca acaatcgcgc tcgcccccca actgacgccg gagaggattg
    16861 ccagcatggc acttttcatc gaagagaaat cgagttgcca cggctgcaac accaaaaata
    16921 agccgaaagc ggcaatcaga atcgcgaaat attgcccacg tcgcaggcgt tcaccgagaa
    16981 acaacgcggc gaaaatcacc acccagaacg gcatggtata gctcaggatc gccaccttcc
    17041 ccgcacctcc gctgaccaac gcccactgcg ccagaccaac catcccgcag gtttgtaaca
    17101 gggcaatggc taaggtgtat ttaaacggtg tcgggcgcat tccgcgacca cgtaataaaa
    17161 ggacgatgaa taaaacgaga gcgccgaaaa tgcagcgtaa ggcggtaaag tcgaaggcac
    17221 cgatgtaact ggtgacttgc ttcatgaaaa tccagctata actccagata agtgtgagca
    17281 caaccaggcc actgattgcc agtgggttgc tctttcctgc ggcagacatg agagatccag
    17341 tgtgtagttt tcgttcgccc actatacgct ggtaaagaac gttcagcgac tgccagcaag
    17401 cagccgctga acggggtcag attacagcag gtcgaaacgg tcgaggttca tcactttcac
    17461 ccatgccgcc acgaagtctt taacaaactt ctcgtgggca tcgctactgg cgtaaacttc
    17521 cgccaccgca cgcaggacgg agttagaacc aaacaccaga tccgcacggc tggccgtaaa
    17581 tttcacttcg ccggtttcac ggtcacggcc ttcgaacagc tctttcgatt cgtcggtcgc
    17641 tttccactcg taacgcatat ccagcaagtt cacgaagaag tcattgctca atacgccaac
    17701 gcggtcagtg aagacgccgt ttttgctgcc atcgaagttg gcacccagta cacgcatgcc
    17761 gcccaccagc gcagtcattt ccggcgcggt cagcgtcagt tgctgtgctt tgtcgatcag
    17821 cagtgactcg gtggtggaaa cgtccagacg agcgcgatag ttacggaaac cgtcagcaat
    17881 tggctccagc agctcaaaca tctcaatgtc agtctgatcc tgacgcgcat caacgcgacc
    17941 cggcgcaaac ggtacatgaa tgctcaaacc tgcggcgctt gcggctttct caacaccaac
    18001 cacaccagcc agcactatga tatccgccag cgaggcttta ccagactctt tctggatttt
    18061 ctccagaaca ggcagagcac gaacggctgc ggcgttcaca tcccagtcgc gctgcggcat
    18121 taatgccaga cgcgcaccgt tggcaccacc gcgtttgtcg ccaccacgga aggtagaagc
    18181 agatgcccag gccaccgata ccagctcact aacagacaga ccagaatccg caatcgcgaa
    18241 tttcagatcg ataatgtcct gctcggtcgg gttgtagatc ggctgcggca gcggatcttg
    18301 ccagatcaga tcttctttcg gcacttccgg cccgatgtag cgagatttcg gccccatatc
    18361 cctgtgcgtc agtttgaacc aggcacgggc aaaggcttcg ttgaacgcct gcggatcgtt
    18421 gaggaaacga cgagagatct tctcgaactc aggatcaaaa cgcagcgtca ggtcggtcac
    18481 cagcattgtc ggtttacgtt tcttcgacgg atcaaacgga tccgggataa tttccggtgc
    18541 gtctaccgct tcgaactgga ttgcgccagc cgggctgcgg gtctgtaccc actcatactt
    18601 gaacaggttc tcgaagaaat agttgctcca ctgggtcggc gtctgggtcc agactacttc
    18661 cagaccagag gtaatggcat ctgcgccaac gccgctgccg taagtgctcg cccaacctaa
    18721 accttgttct tcaatcggtg cagcttctgg atcaggacct acatttgatg tcggaccggc
    18781 accgtgggtt ttacccagcg tatgaccacc cgcaatcagc gccacggttt cttcgtcgtt
    18841 catgcccatg ttgccgaagg tcgcgcggat agctgctgcc gcagaaagcg gttcgccgct
    18901 gtgatccggg ccttccgggt taacgtaaat cagacccatc tcggttgcac ccagcggtgc
    18961 tttcgccagc gcttccggat gacggtgagt cagccaggct ttttcatcac cccagttaac
    19021 atccagatcc ggttcccaga cgtcttcacg accggcacca aaaccgaagg tacggaagcc
    19081 ggagttttct agcgccacgt tacccgcgag gataaacagg tcggcccagg agattttctg
    19141 accatatttc tgtttgattg gccacaacag gcgacgcgct ttatcgaggc ttacgttatc
    19201 cggccaggag ttcagcggtg caaaacgttg ctgaccacga cccgcgccac cgcgtccatc
    19261 gattgaacgg taagtccccg cgccgtgcca ggccatacga ataaacagac cggcgtaact
    19321 gccccagtcg gctggccacc acggttgaga ttctgtcaac agggctttca gatctttttt
    19381 caggccgtag taatctaatt tgctgaattc tttgcggtag tcaaagtcct cacccagtgg
    19441 gttagaacga ttagaatgtt ggtttaacag gtcaacacga agttgatttg gccaccagtc
    19501 gcgagtggtt gtgcccgccc ccgcactctg gtcgtgaccg ccctgatgga acgggcattt
    19561 gccagtggct gtggtgttat ggatatcgtc tgacgtgctc atcaatgtgc tcccctctac
    19621 agtgttaccg ttacgataca cagcgttaga gagaagttat aattgaatta atccacagat
    19681 gcgatagttg agatcttaca tattgttggt taaagagatg tagatcaaat tgatcttaat
    19741 taagcttttt tgattatgtc cgaattcgga caaatgcttt ataaaaaagg gttttagctt
    19801 catatccttc aagtaatgag ggagaaaaca aggctgataa ccttattttc ccgccctcat
    19861 ttcgaggcag cattttgtgc tctgtttaaa atttgtgatc actgtgtgat tttcacaaaa
    19921 gccacactat ttataaacca ggtcgaaccc ccagcgtatg gcaaatcgcg taactcattt
    19981 cagcacggtt aagcgtatag aagtggaaat ctttcactcc ttcacggctt aaaatcttca
    20041 ccatatccat ggcaatattc gcgccaacca gtttgcgggt ttcggcatca tcatccagac
    20101 cgtcgaacat ttgcgccatc cacgccggaa tacgcacgtt ggtcatatcg gcaaatttct
    20161 tcgcctgttt aaagttagat accggcaaaa ttcccggaat aatttccaca tcaatgcccg
    20221 ccgatacaca gcggtcacga aaacgcaggt agctttcgac atcgaagaag aactgagtaa
    20281 tcgcgcggtt ggctccggca tccactttgc gtttcagatt aagcaaatcc gcctgagcgc
    20341 tttttgcttc cgggtgaact tccggatacg ccgccacgga gatatcgaaa tctgccactt
    20401 cttttaacag cgtcaccagg tcagaagcat acatttctgg cttaccactt cccggcggca
    20461 gatcgccacg cagcgccacg atatgacgaa taccgttatt ccagtagtcg cgtgcaatgg
    20521 tgcgcagctc gtcgggcgtc gcatcaatgc aagtaagatg cggtgccgct tccagaccag
    20581 tgcgctcttt aatgccttta ataatgctgt gcgtacggtc gcgctcgccg gagttcgcgc
    20641 cataggtcac cgatacaaac ttcggtttca ggctgctaag gcgatcgatg gagttccaca
    20701 gggtctgctc catttcactg gtacgcggcg ggaaaaactc gaacgaaacg ttaatctgcc
    20761 cctggacttc tgccaggctc tgattcaggg catcccgctg gctggcgtga aaaaagctca
    20821 taccttacct catcaatcgc ttgtagttat atgttgtgtt gtgcacatct atccgtttag
    20881 acgtccagat gtaaagatga aggaaaagcc gaagggcgtc aaccgaaaaa tgaccaatga
    20941 tggtgaggaa aaatcaggga agatgaaaaa acttcaggat ggtaagaaaa agaaaatccg
    21001 gtatgcaaag caaaccggac tgcaaatata aactaaccat gtacttattg cttcttgccg
    21061 gattcgtcgt aaacgcttaa tccggcctaa tcctatgata attcaatata tttcattaga
    21121 aaccataaac ccgaaaacat gagtaccggg cattattaaa tttctgaaat tacaacaact
    21181 gtgccagccg gttgatatcc gactgaatcg ccccggcggt gacgtcgcgc ccagcgccag
    21241 gtccgcggat caccagaggg ttatcgcgat accagcggct ttcgatggca aagacgttat
    21301 cgcacggcag cagtgatgcc aacggatgat cttcacgcac cgcttccacg cctacacgcg
    21361 ctttaccgtt ggcatcgaaa cgcgccacgt agcgcagcac cagccccatt tcgcgggccg
    21421 cttccagccg ttgcaccatc tgctcgttca gttcatcgcc attttcaaag aaatggtcga
    21481 tgctgccgcc ttcgcaatga gcaggcacca gcgattccac acgtacctga tccggttcga
    21541 tgttgtaacc tgcttcacgc gccagaatca ccagcttgcg catcacgtct ttgccagaga
    21601 gatcgtcacg cgggtcaggt tcggttaagc cctgctgcca cgcctgatcc accagctcgg
    21661 taaacggcac gctaccgtcg aattgcagga acagccagga gagcgtgccg gagaagatcc
    21721 cgctgatcga caaaatagta tcgccgctgt cgatcagatc gcgcacggtg tggttgatcg
    21781 gcaagcccgc accgacggtg gcattgtaca gccagtgacg cccggttttt tcgaaggcgt
    21841 cgtggatctg gcgatattta ttgctgtcgc tggctcccgc cagtttgttg gcgctgataa
    21901 cgtggaaacc gtggctggcg aaatcaagat actgatcagc aagctgctgg ctggcggtaa
    21961 cgtccagcac cactaaatca tcatacggat gggcgcgcat ccacaggaac aacgactctt
    22021 catcctgctc aaccgcttca tcgttgaaga aggctaacgc gcggctggcg tccagcccgt
    22081 catagctcaa caggctgcgg cggctgtcca ccacacctgc cagcacaaac tcaaagccgg
    22141 tacgtgccga aagcgtgctc tgctcacggg cgaacagttc cagccaacgg gaaccgatat
    22201 tgcccttacc gaacaatacc aggccgatgc gtttttctgc gcggaagacg gactgatgca
    22261 gcccctgaat caggctttcg gtcgggccgg tgcgcagtac tgccaccagg ctgatgccgt
    22321 catcggactg ccaggtaaat tcgaccggct ggcctttcag ttgctgccag aagcggtggc
    22381 aatgcagcgg gttacgggtg acgcctgcac cgaccatcgc caccagcgcc agcccctgac
    22441 gcaggcgcag ttcgccaggt aatcccgctt cgtcgaggat tttcagcgca ctgtcggcca
    22501 cttctgaggt gtagcaaaat tgcagcaact ggcgatcgtt atgtacgcca accgccagcg
    22561 ggcgtacctg cgcgcgtttc aggatttggt cgatctcttt atgcgccagt ttgaaatcct
    22621 gactggcggg cacctgaaac tcaatcaaac agacatcatc gtggctggtg acaatacgcg
    22681 caccagtacc ggaggccagc acgcgttcaa tgcgcgtgga accttgatcc ggcgtgtagc
    22741 tacagcgcag ttgcaggtcg atttcgctgc cagaaaccgg ctgtaaagta cgggcgtgaa
    22801 gaacgggagc cgccaggcgc gccagttcgc tggcctcatc cagacgcagc aacggcagca
    22861 ggcaggcatc tttcacttta cgcgggtcgg cactgtatac cccggcgacg tcgctccaga
    22921 tggttacgcg agaaacaccc gccagcgcac cgatttgtgt cgcggaatag tcggaaccgt
    22981 tacgccccag cagcaccgtt tcaccggcgt tgttgcggct gataaatccg gtcaccacca
    23041 gacgtttgcc cggatgttgc accagcagct gttgcagcaa cgggtaagaa agcccttcat
    23101 caacctgcgg ttgtgcggcg cgttcagcgc gtaaaaactc gcgggcatca agccaggccg
    23161 ctggcagccc ttgttgatta agtaccgcag acatcagacg tgccgaccat acttccccgt
    23221 ggcccaccac ttccgcatac actgcgtcgt taataccgct gtcgagcagc gccgccaggc
    23281 gctcaaggtc gctgacaaaa gcgctaatga ggctatcggc ttcttcagcg ggtagcagac
    23341 cgctaatcag atcgcactga tagcgacgca gcgtttgttg aacctgatgc gcagagagac
    23401 gatcggtctg gcttagtttc aaccagttaa tcaactggtt agtggtgcta ccggcggcgg
    23461 aaaccaccat catatcgtca ggctgagagt actccgccat aatgcccgcg acacgcaaat
    23521 aacacttcac atcagccaga ctactgccac caaatttatg cagctgacga cctttcgccc
    23581 ctgcctgcgc aatcacactc atttttaccc cttgtttgca gcccggaagc cattttccag
    23641 gtcggcaatt aaatcttcgc catcttcaat accggtggag atacgcagca gcgtctcgga
    23701 gatcccggcg gcagcacgcg cttctggtgc catgcctgca tgtgtcatgg ttgcggcgtg
    23761 agagattaaa ctttccactc cccctaatga ttccgccagc gtaaacaacg acagcccgcc
    23821 caggaaacga cgcagcgtct gctcatcgcc atccagttca aaactcaaca ttgcgccaaa
    23881 gcctttttgc tggcgcgcgg caatttcatg cccctgattt tccggcaacg acgggtgata
    23941 cagttttttc accaacggct gggtttgcag gtatttcaca atcgcctgcg cgttgcgctg
    24001 cgccagctcc atacgcggca ccagcgttcg caacccacgt agcagcagat agctgtcaaa
    24061 cgcgccgccc gtcacgccaa tattgtttgc ccaccaggcc agttcagtga caacgtccgg
    24121 gtctttagca atcaccacgc cggccactac gtctgagtga ccgttcagat atttcgtgca
    24181 tgaatgcaac accagatcgg cacctaatgc cagcggattt tgtaatgccg ggcttaagaa
    24241 ggtgttatcc accacgctca ccgccccgac ttcccttgcc agatggcaga ttttcgcaat
    24301 atccacgacg cgtaacaatg gattacttgg gctttctacc agtaccagtt tgggtttttc
    24361 tgccagcgct gcccgtaatg cctgttcatc gccttgatca acaaacaaca cgcgatagca
    24421 accgcgtttc gccagactgt cgaacaggcg atagctaccg ccgtagcagt cgtgcggcgc
    24481 aaccagcaga tcgccaggtt tcaaaaagac ggtcgttacc aggtgaatcg cggacatgcc
    24541 ggtattagta agtactgcac cagcaccacc ttccagttct gccagcgcac gctgaaccac
    24601 atcgcgcgtt gggttgccgc gacgcgagta atcatgcgcg cgcggttcat taaatccggt
    24661 aaagttatag gtgctggaaa gatggatcgg tgggacaacg caaccatact gttcgtcgtc
    24721 atttaacccg ctacgcactg cgatggtggc ctgtttacgc gtcatgtgat gaagttccct
    24781 gggctttgtc ggtgaaatgt caggcaccag agtaaacatt gtgttaatgg acgtcaatac
    24841 atctggacat ctaaacttct ttgcgtatag attgagcaaa tcccaaatag ccgttaaaat
    24901 tatatgcatt atcacgccga caggtgcatt acacgatgtc acggtaacgc ctgtacggta
    24961 aactatgcgg gtttacggtc agtacccaca tcaactgtgt ggtctggtct caatttattg
    25021 acgaagagga ttaagtatct catggctgaa tggagcggcg aatatatcag cccatacgct
    25081 gagcacggca agaagagtga acaagtcaaa aagattacgg tttccattcc tcttaaggtg
    25141 ttaaaaatcc tcaccgatga acgcacgcgt cgtcaggtga acaacctgcg tcacgctacc
    25201 aacagcgagc tgctgtgcga agcgtttctg catgccttta ccgggcaacc tttgccggat
    25261 gatgccgatc tgcgtaaaga gcgcagcgac gaaatcccgg aagcggcaaa agagatcatg
    25321 cgtgagatgg ggattaaccc ggagacgtgg gaatactaaa gcaaaaaaga gcggcgcgga
    25381 gtggaatcgc ctgatgcgct acgcttatca ggcctacgtc atattgcaat ttattgaatt
    25441 tgcacgaact tgtaggccgg ataaggcgtt cacgccgcat ccggcataaa caacgagcac
    25501 gttgtctgcg acccaccgct ttttatacat ggacgtttaa ctatgaaaaa caggctgctg
    25561 atcctcagcc tgctggtttc tgtacctgcc tttgcctggc agccacaaac cggcgacatc
    25621 atctttcaga tctctcgctc atcgcaaagt aaagcgatcc aactggcgac ccataccgat
    25681 tatagccaca ccggtatgct ggtgatacgc aacaaaaagc cctacgtttt tgaagcagtc
    25741 ggcccggtga aatacacccc gctcaagcag tggatcgccc atggtgaaaa gggcaaatac
    25801 gttgttcgcc gcgttgaagg cggactgagt gttgaacaac agcaaaaact ggcgcaaacg
    25861 gcaaaacgtt atctcggtaa accgtatgat ttcagcttct catggagcga cgatcgccag
    25921 tactgttcgg aagtggtgtg gaaggtttac cagaacgcgc tgggaatgcg cgtgggcgag
    25981 cagcagaagt tgaaagagtt cgacctgagc agcccacaag ttcaggcaaa gctcaaagaa
    26041 cgttacggca agaatattcc gcttgaggaa acggtggtct cgccacaagc cgttttcgat
    26101 gcgccacaac tcaccacggt cgccaaagaa tggccgctgt tttcgtggta atacgaccaa
    26161 aattcaggca caaaaaaagc gccgtgcggc gcttttttcg gaaatccggt cttatttgct
    26221 gcccgggatg ttgaaacgct tgttgaagcg gtcaacacgg ccaccggtag caacatcacg
    26281 ctgtttgcca gtgaagaacg ggtggcactt gctgcacacg tcgaggttca ggtcatgacc
    26341 aacggtggag cggattttca ttacgttacc gcaagagcag ctagcagtaa tttcttcgta
    26401 tttcgggtga atatcttttt tcatgggaaa acctcggttt aaggccgcgt cgctcttcca
    26461 gccctaacgc cagacaccac gcgatgttaa aagtatagct tcaatacgat catttcgtac
    26521 gaaggcgcga aatcatacag aaattaacca gcgtatgcaa actgatccgc actcttctac
    26581 ggcaatgtgt atactaaccc accgaatttc aagtcaggat gatgctatgc ccgttgccca
    26641 cgttgccttg cccgttccgc ttcctcgtac ctttgactat ctgctgccag aaggcatgac
    26701 ggttaaagct gggtgtcgcg tgcgcgtgcc gtttggcaaa cagcaggagc gcatcgggat
    26761 tgtggtatca gttagcgatg ccagcgaact gccgctcaat gagctaaaag cggtagtcga
    26821 agtgctggat agtgagccgg tgtttactca ctccgtctgg cgattgctgc tatgggcggc
    26881 agattactat catcatccga ttggcgatgt gctgtttcat gccttgccga ttttactacg
    26941 ccaggggcgg cctgcggcga acgcgccgat gtggtactgg tttgccactg aacaaggcca
    27001 ggcggtggat ctgaacagcc tgaaacgctc ccccaagcaa caacaggcgc tggcggcgtt
    27061 acggcaaggc aaaatctggc gcgaccaggt cgccacgctc gaatttaatg atgccgcgtt
    27121 gcaggcgcta cgcaaaaaag gtctgtgtga tttagcaagt gaaacaccag agtttagcga
    27181 ctggcgaacg aactatgccg tttctggtga gcggttgcga ttgaataccg aacaggccac
    27241 cgccattggc gcaattcata gcgcggcaga tactttttct gcctggctgc tggcgggcgt
    27301 taccggttcc ggtaaaacgg aggtttatct cagcgtactg gaaaacgtgc tcgctcaggg
    27361 caaacaggcg ctggtgatgg tgccggaaat cggcctgaca ccgcaaacta tcgcccgttt
    27421 tcgtgaacgt tttaatgccc ccgtggaagt tctgcattcc ggcctgaacg acagcgagcg
    27481 tctttcggcg tggctgaaag cgaaaaatgg tgaggcggcg attgtgatcg gcacccgctc
    27541 cgcgctgttt acgccgttta aaaatctcgg cgtgattgtc attgatgaag agcacgacag
    27601 ctcctacaag cagcaggaag gctggcgcta tcatgcccgc gacctggcgg tgtatcgtgc
    27661 gcacagcgag caaatcccga ttattcttgg ctccgcaacg cccgcgctgg aaacgttatg
    27721 caacgtccag cagaaaaaat accgcctgct gcgcctgacc cgtcgggcag ggaatgcgcg
    27781 tccggcaatt caacatgtgc tggatttaaa aggtcagaag gtgcaggcag gtctggctcc
    27841 ggcgttaatc actcgtatgc gccagcattt acaggctgat aaccaggtca ttctctttct
    27901 taaccgccgt ggctttgcgc ctgcactgct gtgccacgac tgtggctgga ttgccgaatg
    27961 cccacgttgc gatcactact acacgctgca tcaggcgcag caccatctgc gctgccacca
    28021 ctgtgacagt cagcgtccgg tgccgcgcca gtgcccttcc tgcggttcca cgcacctggt
    28081 ccccgtgggg ctgggcaccg aacagcttga acagacgctc gcgccgttgt tccccggcgt
    28141 gcccatttct cgtatcgacc gcgataccac cagccgcaaa ggggcgctgg aacagcaact
    28201 ggcagaagta catcgcggcg gcgcgcggat tttgattggt acacaaatgc tggcgaaagg
    28261 tcaccatttc ccggatgtga cgctggttgc attactggac gtggacggcg cgctgttttc
    28321 tgccgatttt cgctcggcag agcgtttcgc tcagctttac acccaggtcg ccggtcgtgc
    28381 cgggcgtgcg ggtaaacagg gcgaagtggt gctgcaaacg caccatccgg aacatcctct
    28441 gttgcaaacg ttgctctata aaggctacga cgcctttgcc gaacaggcgc tggctgagcg
    28501 gcgaatgatg cagctaccgc cgtggaccag ccatgtgatt gtgcgtgcgg aagatcataa
    28561 caatcagcac gcgccattgt tcctgcaaca actgcgtaat ctgatcctct ccagcccact
    28621 ggcagacgag aaactgtggg ttctcggtcc ggttccggct ctggcaccta aacgtggcgg
    28681 tcgctggcgc tggcagatat tgttgcagca cccttcccgc gtgcgcttgc aacacatcat
    28741 taacggtacg ctggcgctca tcaatacaat accggattcc cgtaaggtga aatgggtgct
    28801 ggatgttgat ccgattgagg gttaaaccgc tcacgatgcg aggcggatcg aaaaattcaa
    28861 tattcatcac acttttcatg aaaattctgt aaccgttttc acgcgctatc tgctaaaaat
    28921 gttgccgatg tgaagtaaac atggatgtag tacgcctgac gtgccaggcg aggagtgagt
    28981 gtgaaagcga agaagcagga aactgccgcg accatgaaag acgttgccct caaggcaaaa
    29041 gtctctacag cgaccgtctc ccgagcatta atgaatcccg ataaagtctc ccaggccacc
    29101 cgtaatcggg ttgaaaaagc ggcccgggaa gtgggttatt taccgcagcc tatggggcgc
    29161 aacgtcaagc gtaatgaatc ccgcaccatt ctggtgattg tcccggatat ctgcgatccc
    29221 ttctttagcg aaattattcg cggtatcgaa gttacggcgg caaatcacgg atatctggtg
    29281 ctgattggcg actgtgcgca tcaaaatcag caggaaaaaa cctttatcga tttgatcatc
    29341 accaagcaaa ttgatggcat gttgttgctg ggttcaaggc tgccgtttga tgccagcatt
    29401 gaggaacagc gtaatctgcc gccgatggtg atggcgaacg aatttgcacc ggagctggag
    29461 ctgcctacag ttcatatcga caatctgacc gccgcatttg atgcagtaaa ttatttatat
    29521 gagcaagggc ataaacggat tggctgtata gccggtcccg aagagatgcc gctgtgtcac
    29581 taccgcctgc aaggctatgt tcaggcgctg cgtcgctgcg gcattatggt tgatccgcaa
    29641 tacatcgccc gtggcgactt caccttcgaa gccggaagca aagcgatgca gcagctgctt
    29701 gatcttccac aaccgcctac tgctgtcttc tgccatagcg atgtgatggc gctcggcgca
    29761 ctttctcagg caaaacgcca ggggctgaaa gtcccggaag acctttccat aatcggtttt
    29821 gataacatcg acctgacgca attttgtgat ccgccgctga caaccatcgc gcagccgcgt
    29881 tacgaaatcg gtcgggaagc tatgctgtta ttgcttgatc aaatgcaggg gcaacacgtt
    29941 ggcagtggct ctcgtttaat ggactgcgaa cttatcatcc ggggatcaac acgcgcgtta
    30001 ccttaaagta aacctttaag actgccgtga ctggtcaaag gcccgccgct taagtaacat
    30061 ggcgggctga cgaacgaata aatacagcga aacgatagtg gcacaacgag attatgtacg
    30121 ccgcagccaa ccggcacctt cgcggcgaaa aaagagcacc tcacggaaaa agcaacgaaa
    30181 tctgcctgcg gtttctcccg ctatggtcgc tattgctgcc gccgttcttg tgacctttat
    30241 cggtggtctg tacttcatta cgcatcacaa gaaagaagag tccgagacgc tgcaaagcca
    30301 gaaagtgacc ggaaacggac taccaccaaa accagaagaa cgctggcgct acattaaaga
    30361 gctggaaagt cgccagccgg gagtgcgtgc gcccacagaa ccttctgccg gtggtgaagt
    30421 gaaaacgccg gagcaactga caccagaaca acgtcagctt cttgaacaaa tgcaggctga
    30481 tatgcgccag cagccaacgc agctggttga agttccgtgg aatgaacaga cgccggaaca
    30541 gcgtcagcaa acgctacagc gccaacgtca ggcgcagcaa ttagcggaac agcaacgcct
    30601 ggctcagcag tcgcgtacga ctgaacaaag ctggcagcag cagacgcgta cgtcgcaagc
    30661 cgcaccggta caggcgcaac cgcgccagtc taaaccggct tcttctcagc agccgtacca
    30721 ggatctgctg caaactcctg cgcacacgac tgcgcagtcg aagccgcagc aagctgcgcc
    30781 agttgctcgt gccgctgacg cgccaaaacc gacggcggag aaaaaagacg aacgccgctg
    30841 gatggtgcag tgcggttcgt tcagaggcgc ggaacaggca gagacggtac gtgctcagct
    30901 ggcgttcgaa ggctttgact cgaaaatcac caccaacaat ggctggaatc gtgtggtcat
    30961 tggcccggtg aaaggcaaag agaacgcaga cagcaccctc aatcggttga agatggcggg
    31021 tcatacaaac tgcattcggc tcgccgccgg gggttgaaac cctcaaaatc ccccccatct
    31081 ataattgcat tatgccccgt acttttgtac ggggtttgta ctctgtattc gtaaccaagg
    31141 ggtcagctcg tgacaactat agtaagcgta cgccgtaacg gccatgtggt catcgctggt
    31201 gatggtcagg ccacgttggg caataccgta atgaaaggca acgtgaaaaa ggtccgccgt
    31261 ctgtacaacg acaaagtcat cgcgggcttt gcgggcggta ctgcggatgc ttttacgctg
    31321 ttcgaactgt ttgaacgtaa actggaaatg catcagggcc atctggtcaa agccgccgtt
    31381 gagctggcaa aagactggcg taccgatcgc atgctgcgca aacttgaagc actgctggca
    31441 gtcgcggatg aaactgcatc gcttatcatc accggtaacg gtgacgtggt gcagccagaa
    31501 aacgatctta ttgctatcgg ctccggcggc ccttacgccc aggctgcggc gcgcgcgctg
    31561 ttagaaaaca ctgaacttag cgcccgtgaa attgctgaaa aggcgttgga tattgcaggc
    31621 gacatttgca tctataccaa ccatttccac accatcgaag aattaagcta caaagcgtaa
    31681 ggatctccca tgtctgaaat gaccccacgc gaaatcgtca gcgaactgga taagcacatc
    31741 atcggccagg acaacgccaa gcgttctgtg gcgattgctc tgcgtaaccg ctggcgtcgc
    31801 atgcagctca acgaagagct gcgccatgaa gtgaccccga aaaatatcct gatgatcggc
    31861 ccgaccggtg tcggtaaaac tgaaatcgcc cgtcgtctgg ctaagctggc gaatgcgccg
    31921 ttcatcaaag ttgaagcgac caaattcacc gaagtgggct acgtcggtaa ggaagtggat
    31981 tctattattc gcgatctgac cgatgccgcc gtgaaaatgg tacgcgtcca ggctatcgag
    32041 aaaaaccgtt atcgcgctga agaactggca gaagaacgta ttctcgacgt gctgatccca
    32101 cctgctaaaa acaactgggg acagaccgaa cagcagcagg aaccgtccgc tgctcgtcag
    32161 gcattccgca aaaaactgcg tgaaggccag cttgatgaca aagaaatcga gatcgatctt
    32221 gccgcagcac cgatgggcgt tgaaattatg gctcctccgg gcatggaaga gatgaccagc
    32281 cagctgcagt ccatgttcca gaacctgggc ggccagaagc aaaaagcgcg taagctgaaa
    32341 atcaaagacg ccatgaagct gctgattgaa gaagaagcgg cgaaactggt gaacccggaa
    32401 gagctgaagc aagacgctat cgacgctgtt gagcagcacg ggatcgtgtt tatcgacgaa
    32461 atcgacaaaa tctgtaagcg cggcgagtct tccggtccgg atgtttctcg tgaaggcgtt
    32521 cagcgtgacc tgctgccgct ggtagaaggt tgcaccgttt ccaccaaaca cgggatggtc
    32581 aaaactgacc acattctgtt tatcgcttct ggcgcgttcc agattgcgaa accgtctgac
    32641 ctgatcccgg aactgcaagg tcgtctgcca atccgcgttg aactgcaggc gctgaccacc
    32701 agcgacttcg agcgtattct gaccgagccg aatgcctcta tcaccgtgca gtacaaagca
    32761 ctgatggcga ctgaaggcgt aaatatcgag tttaccgact ccggtattaa acgcatcgcg
    32821 gaagcggcat ggcaggtgaa cgaatctacc gaaaacatcg gtgctcgtcg tttacacact
    32881 gttctggagc gtttaatgga agagatttcc tacgacgcca gcgatttaag cggtcaaaat
    32941 atcactattg acgcagatta tgtgagcaaa catctggatg cgttggtggc agatgaagat
    33001 ctgagccgtt ttatcctata atcgcgttca atcattttca tcattgtttg atggggctga
    33061 aaggccccat ttttattggc gcgtattatg actgaacaac aaattagccg aactcaggcg
    33121 tggctggaaa gtttacgacc taaaaccctc cccctcgcct ttgctgcaat tatcgtcggg
    33181 acagcgctgg catggtggca aggtcacttc gatccgctgg tcgccctgct ggcactaatt
    33241 accgccgggc tattacagat cctttctaac ctcgccaatg attacggcga tgcggtaaaa
    33301 ggcagcgata aacctgaccg cattgggccg ctacgcggca tgcaaaaagg ggtcattacc
    33361 cagcaagaga tgaaacgggc gctcattatt accgtcgtgc tcatctgtct ctccgggctg
    33421 gcactggttg cagtggcatg ccatacgctg gccgattttg tcggtttcct gattcttggc
    33481 gggttgtcga tcattgccgc tatcacctac accgtgggca atcgtcctta tggttatatc
    33541 ggtctgggtg atatttccgt actggttttc tttggctggt tgagtgtcat ggggagctgg
    33601 tatttacagg ctcatacatt gattccggca ctgatccttc cggcgaccgc atgcggcctg
    33661 ctggcaacgg cagtactgaa tattaataac ctgcgtgata tcaatagcga ccgcgaaaat
    33721 ggcaaaaaca cgctggtggt gcgcttaggt gaagtgaacg cgcgtcgtta tcatgcctgc
    33781 ctgctgatgg gctcgctggt gtgtctggcg ctgtttaatc tcttttcgct gcatagcctg
    33841 tggggctggc tgttcctgct ggcggcacca ttactggtga agcaagcccg ttatgtgatg
    33901 cgggaaatgg acccggtggc gatgcgacca atgctggaac gtactgtcaa gggagcgtta
    33961 ctgactaacc tgctgtttgt tttagggata ttcctaagcc agtgggcagc ataactgaca
    34021 aatatcaatt aacaattgat gattttgcca acagcccaca tagcgcgata tactgaaaat
    34081 tctcgcagca actgaatgtt aagcctatga aatacgatac ttccgagctt tgtgacatct
    34141 atcaagaaga tgttaacgtc gtggaaccgc tgttctccaa ctttggcgga cgggcgtcgt
    34201 ttggcggaca aataatcacg gtaaaatgtt tcgaggacaa cgggttgctg tacgatctgc
    34261 tcgaacagaa tggccgtggt cgtgttcttg tcgtcgatgg cggtggttct gttcgtcgcg
    34321 cactggtcga tgctgaactg gcgcgtctgg cagtacaaaa tgaatgggaa ggtctggtca
    34381 tttacggcgc ggtgcgtcag gtagatgacc tggaagagtt ggatatcggc atccaggcga
    34441 tggcggcaat tccggttggt gccgctggcg aaggcattgg cgaaagcgat gtccgcgtca
    34501 attttggcgg tgtcaccttc ttctccggcg accatcttta tgccgacaat accgggatta
    34561 ttctttcaga agatccgctg gatattgaat gataagaaag gcaccgcaag gtgccttttt
    34621 tctgcgttac ctgttggcct acacagtaaa gaaattacgc ggaagatgaa gcgtaatcag
    34681 acctcttcca tgcgacccag cagggcctgc agacgttcct gccagccgtt ctgctgttct
    34741 ttcagatggt tgttctcacg ctccagctct tcgcgctgat gctgggcatt ttgaacttcc
    34801 tgcgacagtg agttgttttt ttctttcagc tcttcgattt ccatctgcaa cagagtgatg
    34861 gtatcaatcg cctgctgtac ttttgcttcc agtttctcaa acacttctaa tgacattgtc
    34921 atacctctcc tgaattgcaa ggcgttgatg gataaaaatc ctcgtcccga ttaccggtga
    34981 cgccttaata aatacgagcg cactttagtt agctccgatt gtatgaagcc gcgccatcgc
    35041 tgtccagcgg cacgccttgc agattacggt ttgccacact tttcatcctt ctcctggtga
    35101 cataatccac atcaatcgaa aatgttaata aatttgttgc gcgaatgatc taacaaacat
    35161 gcatcatgta caatcagatg gaataaatgg cgcgataacg ctcattttat gacgaggcac
    35221 acacatttta agttcgatat ttctcgtttt tgctcgttaa cgataagttt acagcatgcc
    35281 tacaagcatc gtggaggtcc gtgactttca cgcatacaac aaacattaac tcttcaggat
    35341 ccgattatga gtcaaacatc aaccttgaaa ggccagtgca ttgctgaatt cctcggtacc
    35401 gggttgttga ttttcttcgg tgtgggttgc gttgcagcac taaaagtcgc tggtgcgtct
    35461 tttggtcagt gggaaatcag tgtcatttgg ggactggggg tggcaatggc catctacctg
    35521 accgcagggg tttccggcgc gcatcttaat cccgctgtta ccattgcatt gtggctgttt
    35581 gcctgtttcg acaagcgcaa agttattcct tttatcgttt cacaagttgc cggcgctttc
    35641 tgtgctgcgg ctttagttta cgggctttac tacaatttat ttttcgactt cgagcagact
    35701 catcacattg ttcgcggcag cgttgaaagt gttgatctgg ctggcacttt ctctacttac
    35761 cctaatcctc atatcaattt tgtgcaggct ttcgcagttg agatggtgat taccgctatt
    35821 ctgatggggc tgatcctggc gttaacggac gatggcaacg gtgtaccacg cggccctttg
    35881 gctcccttgc tgattggtct actgattgcg gtcattggcg catctatggg cccattgaca
    35941 ggttttgcca tgaacccagc gcgtgacttc ggtccgaaag tctttgcctg gctggcgggc
    36001 tggggcaatg tcgcctttac cggcggcaga gacattcctt acttcctggt gccgcttttc
    36061 ggccctatcg ttggcgcgat tgtaggtgca tttgcctacc gcaaactgat tggtcgccat
    36121 ttgccttgcg atatctgtgt tgtggaagaa aaggaaacca caactccttc agaacaaaaa
    36181 gcttcgctgt aatatgacta cgggacaatt aaacatgact gaaaaaaaat atatcgttgc
    36241 gctcgaccag ggcaccacca gctcccgcgc ggtcgtaatg gatcacgatg ccaatatcat
    36301 tagcgtgtcg cagcgcgaat ttgagcaaat ctacccaaaa ccaggttggg tagaacacga
    36361 cccaatggaa atctgggcca cccaaagctc cacgctggta gaagtgctgg cgaaagccga
    36421 tatcagttcc gatcaaattg cagctatcgg tattacgaac cagcgtgaaa ccactattgt
    36481 ctgggaaaaa gaaaccggca agcctatcta taacgccatt gtctggcagt gccgtcgtac
    36541 cgcagaaatc tgcgagcatt taaaacgtga cggtttagaa gattatatcc gcagcaatac
    36601 cggtctggtg attgacccgt acttttctgg caccaaagtg aagtggatcc tcgaccatgt
    36661 ggaaggctct cgcgagcgtg cacgtcgtgg tgaattgctg tttggtacgg ttgatacgtg
    36721 gcttatctgg aaaatgactc agggccgtgt ccatgtgacc gattacacca acgcctctcg
    36781 taccatgttg ttcaacatcc ataccctgga ctgggacgac aaaatgctgg aagtgctgga
    36841 tattccgcgc gagatgctgc cagaagtgcg tcgttcttcc gaagtatacg gtcagactaa
    36901 cattggcggc aaaggcggca cgcgtattcc aatctccggg atcgccggtg accagcaggc
    36961 cgcgctgttt ggtcagttgt gcgtgaaaga agggatggcg aagaacacct atggcactgg
    37021 ctgctttatg ctgatgaaca ctggcgagaa agcggtgaaa tcagaaaacg gcctgctgac
    37081 caccatcgcc tgcggcccga ctggcgaagt gaactatgcg ttggaaggtg cggtgtttat
    37141 ggcaggcgca tccattcagt ggctgcgcga tgaaatgaag ttgattaacg acgcctacga
    37201 ttccgaatat ttcgccacca aagtgcaaaa caccaatggt gtgtatgtgg ttccggcatt
    37261 taccgggctg ggtgcgccgt actgggaccc gtatgcgcgc ggggcgattt tcggtctgac
    37321 tcgtggggtg aacgctaacc acattatacg cgcgacgctg gagtctattg cttatcagac
    37381 gcgtgacgtg ctggaagcga tgcaggccga ctctggtatc cgtctgcacg ccctgcgcgt
    37441 ggatggtggc gcagtagcaa acaatttcct gatgcagttc cagtccgata ttctcggcac
    37501 ccgcgttgag cgcccggaag tgcgcgaagt caccgcattg ggtgcggcct atctcgcagg
    37561 cctggcggtt ggcttctggc agaacctcga cgagctgcaa gagaaagcgg tgattgagcg
    37621 cgagttccgt ccaggcatcg aaaccactga gcgtaattac cgttacgcag gctggaaaaa
    37681 agcggttaaa cgcgcgatgg cgtgggaaga acacgacgaa taatgtaaat gccgaatgaa
    37741 gcgtttatgc cgcatccggt agtcccgaaa cgtgcggggg caaccccgca cacatcaata
    37801 atccctccct tcccctgtgc tacacttcgc gccattcctt actgcttaga gtttgctatg
    37861 agacgagaac ttgccatcga attttcccgc gtcaccgaat cagcggcgct ggctggctac
    37921 aaatggttag gacgcggcga taaaaacacc gcggacggcg cggcggtaaa cgccatgcgt
    37981 attatgctca accaggtcaa cattgacggc accatcgtta ttggtgaagg tgaaatcgac
    38041 gaagcaccga tgctctacat tggtgaaaaa gtcggtactg gtcgcggcga cgcggtagat
    38101 attgctgttg atccgattga aggcacgcgc atgacggcga tgggccaggc taacgcgctg
    38161 gcggtgctgg cagtaggcga taaaggctgc ttcctcaatg cgccggatat gtatatggag
    38221 aagctgattg tcgggccggg agccaaaggc accattgatc tgaacctgcc gctggcggat
    38281 aacctgcgca atgtagcggc ggcgctcggc aaaccgttga gcgaactgac ggtaacgatt
    38341 ctggctaaac cacgccacga tgccgttatc gctgaaatgc agcaactcgg cgtacgcgta
    38401 tttgctattc cggacggcga cgttgcggcc tcaattctca cctgtatgcc agacagcgaa
    38461 gttgacgtgc tgtacggtat tggtggcgcg ccggaaggcg tagtttctgc ggcggtgatc
    38521 cgcgcattag atggcgacat gaacggtcgt ctgctggcgc gtcatgacgt caaaggcgac
    38581 aacgaagaga atcgtcgcat tggcgagcag gagctggcac gctgcaaagc gatgggcatc
    38641 gaagccggta aagtattgcg cctgggcgat atggcgcgca gcgataacgt catcttctct
    38701 gccaccggta ttaccaaagg cgatctgctg gaaggcatta gccgcaaagg caatatcgcg
    38761 actaccgaaa cgctgctgat ccgcggcaag tcacgcacca ttcgccgcat tcagtccatc
    38821 cactatctgg atcgcaaaga cccggaaatg caggtgcaca tcctctgatt gatttgatcg
    38881 attgagcctt ccagtccttc gggactggaa tttttttgtt cggagaacga agataaggca
    38941 agtcaatcaa aacaggagaa aaacatggct gattgggtaa caggcaaagt cactaaagtg
    39001 cagaactgga ccgacgccct gtttagtctc accgttcacg cccccgtgct tccgtttacc
    39061 gccgggcaat ttaccaagct tggccttgaa atcgacggcg aacgcgtcca gcgcgcctac
    39121 tcctatgtaa actcgcccga taatcccgat ctggagtttt acctggtcac cgtccccgat
    39181 ggcaaattaa gcccacgact ggcggcactg aaaccaggcg atgaagtgca ggtggttagc
    39241 gaagcggcag gattctttgt gctcgatgaa gtgccgcact gcgaaacgct atggatgctg
    39301 gcaaccggta cagcgattgg cccttattta tcgattctgc aactaggtaa agatttagat
    39361 cgcttcaaaa atctggtcct ggtgcacgcc gcacgttatg ccgccgactt aagctatttg
    39421 ccactgatgc aggaactgga aaaacgctac gaaggaaaac tgcgcattca gacggtggtc
    39481 agtcgggaaa cggcagcggg gtcgctcacc ggacggatac cggcattaat tgaaagtggg
    39541 gaactggaaa gcacgattgg cctgccgatg aataaagaaa ccagccatgt gatgctgtgc
    39601 ggcaatccac agatggtgcg cgatacacaa cagttgctga aagagacccg gcagatgacg
    39661 aaacatttac gtcgccgacc gggccatatg acagcggagc attactggta agcggttact
    39721 tatcgataaa cggcacgatg agcaaatccg cactcatctt attgatcatc ccgcgatatg
    39781 ccggcatcaa acggttgata aatgagtgat gatgaccaca gacaaggagg tcgcactgct
    39841 ctttttgcat aatttccagc agtgtttccg gcatttctcc gcgttcaata cgcagttttg
    39901 tcttcggcca ttgaatattt ttcgtcagtt tatatagctt gttatccgac ttattcttca
    39961 acaattgaag aatatcttct gttgcaggga agtagatacc cggatacaac tcgcttaagc
    40021 catcatcaat atgaattaac gtcaggtgag cgtcattatg tctggcgagc tccagggctt
    40081 tattcaccag taaggcatct tcttcattct cggaaattgc cacgccaatg tgtttataag
    40141 ccatgtttaa ctccttctaa agcaactcca tcaagctaac gaacgcagtg ataactcaaa
    40201 aataatcatc tcggcctggc atgagaaagt gaaggccgca tcaagctcaa cttgcccctc
    40261 cagatcctta atcttatagg ccacgctggc cccttcatct gcagaggatg tagcggcggc
    40321 aagctctttc agtttggtca taaaagactc tgcttcttcg cgggtggcaa aaaagcgcga
    40381 aaacttactg gtacagttgt cgttatcaat caccgtaccg atatcaatcg cacatccttt
    40441 agtactgcat ttatctacga catctttcat agggcacctc tgtatattcg cctctctgtc
    40501 gattacgact taagaataat gcgccgttaa gggaagaaca aacaagtaat gatcttatgg
    40561 attaccattt tttttgatat tgcttaaggt gaagagttca gaaggatttt ccgggtattg
    40621 tcatttgcat cgtggaaata acaatcccgg aaaaaaatag cagtaagaga tatattaaag
    40681 gttaattact tgatttattg tcggctttat acttcacatc ctgagtatct ttaccatatt
    40741 tattttcgcc ttgtgtgcca acaaacgcac caagatcgat aagcatcatc accagaatca
    40801 acgtcgggac aaaacgcccc accgcccatt gccagacacc cggtaaaatc gcccagttac
    40861 ccgccagcag catccacgcc acaatcatca gaaatgccca tgcgccggaa cgcccgcgat
    40921 catgcaagcg cttaacagtt actgccgctg ttggccagag caagcacaca aggcaaaacg
    40981 ccgcggtctg aatatcgagt agattcttac ccgccagtga gaaaagcacc agcatgcctg
    41041 cgaaccacag gcctatccaa atccagaaat cacggcgtcc aatacgccct ttaaatgaga
    41101 ataaccattg ctgtatggtc atgtaagttc cttgatggtt gtcttttcca ggattctacc
    41161 cttttgacaa gggcgacaga tatcgtttta atcggagcca gtcataacaa aaggtactgt
    41221 caatgaagcc agggtgtacg ctgttttttc tcttatgttc tgcattaacc gttacaacag
    41281 cggcgcatgc acaaacacca gatacggcaa cgaccgcgcc ttatctgctg gctggagccc
    41341 ctactttcga tctctccatc agccagtttc gagaagactt taacagccag aatcccagcc
    41401 tgccactgaa cgaatttcgt gccatcgaca gcagtcccga caaagccaat ctcactcgtg
    41461 ctgcaagtaa aattaatgag aacttgtatg cttctacagc gctggagcgc ggtaccttaa
    41521 aaatcaaaag cattcaaatg acctggctac ccatccaggg gccagagcaa aaagccgcga
    41581 aagcgaaagc tcaggaatac atggcagcgg tgatccgcac actcacccca ttaatgacca
    41641 aaacacaaag ccagaaaaaa ctgcagtcgc tactaacggc ggggaaaaac aaacgttatt
    41701 acaccgagac agaaggtgca ctgcgttatg ttgtcgcgga caacggcgaa aaggggctga
    41761 ccttcgctgt tgaaccgatt aagctggcgc tatctgaatc gcttgaaggt ttgaataaat
    41821 gacaaaaagc aaagcctttg tgccgatgaa tctctatact gtttcacaga cctgctgccc
    41881 tgcggggcgg ccatcttcct ttattcgctt ataagcgtgg agaattaaaa tgcgacatcc
    41941 tttagtgatg ggtaactgga aactgaacgg cagccgccac atggttcacg agctggtttc
    42001 taacctgcgt aaagagctgg caggtgttgc tggctgtgcg gttgcaatcg caccaccgga
    42061 aatgtatatc gatatggcga agcgcgaagc tgaaggcagc cacatcatgc tgggtgcgca
    42121 aaacgtggac ctgaacctgt ccggcgcatt caccggtgaa acctctgctg ctatgctgaa
    42181 agacatcggc gcacagtaca tcatcatcgg tcactctgaa cgtcgtactt accacaaaga
    42241 atctgacgaa ctgatcgcga aaaaattcgc ggtgctgaaa gagcagggcc tgactccggt
    42301 tctgtgcatc ggtgaaaccg aagctgaaaa tgaagcgggc aaaactgaag aagtttgcgc
    42361 acgtcagatc gacgcggtac tgaaaactca gggtgctgcg gcattcgaag gtgcggttat
    42421 cgcttacgaa cctgtatggg caatcggtac tggcaaatct gcaactccgg ctcaggcaca
    42481 ggctgttcac aaattcatcc gtgaccacat cgctaaagtt gacgctaaca tcgctgaaca
    42541 agtgatcatt cagtacggcg gctctgtaaa cgcgtctaac gctgcagaac tgtttgctca
    42601 gccggatatc gacggcgcgc tggttggtgg tgcttctctg aaagctgaaa ccttcgcagt
    42661 aatcgttaaa gctgcagaag cggctaaaca ggcttaagtc tgacaggtgc cggatttcat
    42721 atccggcact tactttcctt aactcttcgc cttaacgcaa aatctcacac tgatgatcct
    42781 gaatttcctc ggctgaagca cggttaagcg tcagtagatt tcgttgtgtc gccagcaata
    42841 caaatgagtt atcactctgc cgtaccatcg ccagcccgta gcgtcccata tgttcccgcg
    42901 cctcaggtac ttcttctgcc agcatcataa atgggctgcg ttgtaccagt tcgctttccg
    42961 ttacccgacg cgccaggtat tcatgcccgc gcaaaccacc tggcagtggc aaccagcggc
    43021 tgctgatgtt cgccagattg ttatccagct gtttgcgcac atcaggacga atacaagaga
    43081 tatgaatatg aaaatggttt tgcgtacgcc cggtgcggga gttgatcgcc aaagaaaccg
    43141 cgcgatcggg aaccggctgg ccgtattttt tgctcataaa atcacgcgcc tgccaagcca
    43201 accaaaagaa gttcggcgtt gaaggatcgg tcaacaaagg actttcagta ccgttaatac
    43261 gatacgttgg catcaacaga tattgcagtg ggccattaag atcttttaaa accacgtatc
    43321 cggcattggg tttgacttcc gcacatggcg aaggattttg attttgctgc tgattgggca
    43381 aacattcctc aaggacaatc ttacgtaatg tatccgactc ttcaccggtt aatttccagt
    43441 aaccaatacc ggcagccaca acggcgataa ctatcatcac caaaaaaaga agacccgctt
    43501 ttttcatctt tttttccctg tacctcaaag agatgcaagg gtaacgcaaa atcgtgacaa
    43561 ataaaaaacc cggtcgcgag aaaccaccgg gtttgataat tatcctgggg aaatcagcgt
    43621 ttgctgatct gatcgaacgt accgccgtta gcaaaatgct ctttttgcgc tttcgtccag
    43681 ccgccgaact cttcatcaat ggtgaataac ttcagctttg gaaacgcatt ttcgtacttt
    43741 ttcgccacct cagcgtcgcg cggacggtag tagtttttcg cggcaatttc ctgaccttct
    43801 ggcgagtaga gatatttcag gtaggcttcc gccacctctt tagtaccttt tttctcgacc
    43861 actttatcga ccaccgacac ggttggctct gcgaggatag actcactcgg cgtgacgatt
    43921 tcgaatttat ctttccccag ttcattcgct gccagcagag cttcgttttc ccaggcaatc
    43981 agtacatcgc caattccgcg ctcgacaaaa gtgttagtgg agccacgcgc gccagaatcc
    44041 agaacttcga cgtttttata cagtgcccga ataaaatcct gtgcttttgc ctgatcgttg
    44101 ttgttgtgat gcagcgcgta gccccaggct gccaggtagt tccagcgcgc gccaccagag
    44161 cttttcggat taggcgtgat caccgaaaca cccggtttaa tcagatcgtt ccagtcatgg
    44221 atctgcttcg gatttccctt acgtaccagg aaaacaatgg tggaagtgta cggtgcggag
    44281 ttatccggca gacgtttgat ccactcttta tcaatccgcc cgcgttccgc aattgcgtcc
    44341 acgtcatagg ccagagccag cgtgacaaca tcagcttcaa taccgttgat taccgacgtc
    44401 gcttgtttac ctgagccacc gtgtgactga cgaatcacca cgttatcacc agtttgctgt
    44461 ttccagtggg cgctgaatgc cttgttgtac tgttcgtaca attcgcgcgt tggatcatat
    44521 gaaacgttaa gaagctgaat atcctttgcc ataacgctgg ttgccgccag caaaaatgtt
    44581 aaccctacgc cccacttgtt catcgcccga ctctcttatg ttgtgttgtg atgagcaaag
    44641 cgtgccagaa ggttaaccaa acattaaaga ataaaaaaag attggctata acttgcgggt
    44701 atatgttgag ggattaaaaa ggcggaagaa atccgcctca tattgctgac aaagtgcgct
    44761 ttgtccatgc cggatgcggc gcgaacgcct tatccggcct acaaaagttt gcaaattcaa
    44821 taaattgcag aattcatgta ggcctgataa gcgaagcgca tcaggcattt ttgcttctgt
    44881 catcggtttc agggtaaagg aatctgcctt tttccgaaat cattaataca gttttttcgc
    44941 gcagtccagc cagtcacctt tgaacggacg cttcatgttt tcgatagcgt cgatgatgtc
    45001 gtggtgaacc agctgttcgt tctggatacc tacacaacga ccgccgtaac ctgccagcag
    45061 cagatcgata gcgtaagcgc ccatacggga agccagaata cggtcgtaag gcaccggaga
    45121 accaccgcgc tggatgtggc ccagcacagt tgcgcgggtt tcacgaccgg tttctttctc
    45181 gatgaaatgc gccagttcgt caacatcaca catatgttcg gtaatcgcca cgatcgcgtg
    45241 ttttttacct ttcgcgatac ccgctttgat ttcgtttacc aggtcttcac ggctgaattc
    45301 aacttccgga accacaacga attcacagcc accggcaatg gccgcagcca acgtcagatc
    45361 tccacaataa cggcccatca cttccaccac ggaaatacgc tggtgagaag aagaggtgtc
    45421 acgcagacgg tcgatcgctt ctacaacggt gctcagcgca gtgaagaaac cgatagtgta
    45481 gtcagtgcct ttgatgtcgt tgtcgatagt gcccggcaga ccgatgcacg ggaagcccat
    45541 ttcggtcaga cgcattgcac ccatgtagga accgtcaccg ccgataacca ccagcgcgtc
    45601 gataccacgt tttttcaggt tttcgatagc cacggcgcgg atgttctcgt cgcggaattc
    45661 cgggaaacgc gcagaaccga ggaacgtacc gccacggttg atcatgtcag acacgctgta
    45721 acggtctagc tgtaccatac ggtcttcata cagacccaga tagccgtcat aaatacccat
    45781 tacttccaga ccttctgtca gcgcagaacg aacaaccccg cgaattgcgg cgttcatgcc
    45841 tggcgcatca ccgccgcttg tcaacacacc gattttctta atcatgacta cctctgaact
    45901 ttggaatgca aaatgaaatc tgttgccgga agtcttcttg cacatcgaag tgatccaacg
    45961 aatgtgcaaa tagtataaca atcacttcct gctgaattga ttcaggtcag gccaaatggc
    46021 ggtattttat acacaaaatg cgggtctggc tctcttttat actgattatg aaagcataga
    46081 ccgtttaccc tccctgggta cgacggaaca ggggtcctga tggataatta catccgatcc
    46141 cggaaaacgc cgtaaaatag cctgctctac ctgatccgcc accatatgtg cctgaaccaa
    46201 aggcagagag tcttccattt ccaaatgaat ctgaataaag cgggtcggcc ctgactgccg
    46261 cgtgcgaaga tcgtgagcgc cgctaacacc cggccaggaa gtcacgatat caataatttc
    46321 ttgccgttcc tcatcaggca atgcgcgatc cagtaatgac tgtaccgcct catatcccat
    46381 gcgtaacgcg ctatataaaa tatagatgcc gattcccaat gcaaacagag catcggcgcg
    46441 atgccagccg taccaggaca accccagcgc cagcagaatt gcgccgttca tcataacatc
    46501 agactggtaa tgtagcatat cagcccgcac agcctggctt tgcgtccgcc gcaccaccca
    46561 acgctgaaac gagacaagga taatcgtaca aattagcgcc acaattgtca cgataacccc
    46621 gacgcctgga tctgtcatcg gtgttggaga tatcagatgt tgaatacccg tcaaaaacag
    46681 gaatagtgcc gaaccggaga taaacatact ttgcgccagc gccgcgaggg actcagcttt
    46741 accgtgacca aacgagtgat tatcgtcggc aggttgcagg gaatatcgca ccaccaataa
    46801 attcgtcaac gacgcgccga tatccaccag cgaatccacc agcgcggcga gaatactcac
    46861 cgacccggta taccaccatg caaaaatttt aatcagcaat agcagcgaag ccatcgccgt
    46921 cgcagcaatc gccgcccgac tgaccagccg tccataagat tgattcataa atactcccgc
    46981 tatcaactga cgctagtata acggaagcaa atcatctgca atgcattaag cagcaggcaa
    47041 attgaggata aaaaaaaccc ccacagcatg tgggggaaga cagggatggt gtctatggca
    47101 aggaaaacag ggtttactac tgggaacgtg agttgctact actcaatagc ttcaacgatg
    47161 aacttttttg ccattgcgtc acgtcacgca actgctccat tcgttgttga tgtttctcgt
    47221 ttaaaaccgc ttgctgctcc ggcgttaaca ggcgatacat ttggttgcgg acttttgcca
    47281 tctcaacctg acgagcaatt tgctcattcg ccattttttc tgcctgtgcg cgcacagcgt
    47341 tttcatcaaa attttctgcg gtgacaaggc gatgcattgt ctccagttcg ctaacattaa
    47401 caggaggctg ttcgtgccgg gcctgttgca taagatctcg catctgctga cgctgatgtt
    47461 cggttaaact tatgccgtcg aacatatggc tctgcgtact gcgctgcgta agttcttcac
    47521 ccggatgcca gttatcgcct gaaccgactt cagcagcgtg gcttaatgaa ctgactgcca
    47581 gcgttgaggc catgacggca gcggtaacta tgcgcatcat ttgctcccaa aatctttctg
    47641 tcgcgattca acgatagaga gtttacgatt caggctgcaa acatgcgtca gggggtgtaa
    47701 aacaacgtaa agtcatggat tagcgacgtc tgatgacgta atttctgcct cggaggtatt
    47761 taaacaatga ataaaatcct gttagttgat gatgaccgag agctgacttc cctattaaag
    47821 gagctgctcg agatggaagg cttcaacgtg attgttgccc acgatgggga acaggcgctt
    47881 gatcttctgg acgacagcat tgatttactt ttgcttgacg taatgatgcc gaagaaaaat
    47941 ggtatcgaca cattaaaagc acttcgccag acacaccaga cgcctgtcat tatgttgacg
    48001 gcgcgcggca gtgaacttga tcgcgttctc ggccttgagc tgggcgcaga tgactatctc
    48061 ccgaaaccgt ttaatgatcg tgagctggtg gcacgtattc gcgcgatcct gcgccgttcg
    48121 cactggagcg agcaacagca aaacaacgac aacggttcac cgacactgga agttgatgcc
    48181 ttagtgctga atccaggccg tcaggaagcc agcttcgacg ggcaaacgct ggagttaacc
    48241 ggtactgagt ttaccctgct ctatttgctg gcacagcatc tgggtcaggt ggtttcccgt
    48301 gaacatttaa gccaggaagt gttgggcaaa cgcctgacgc ctttcgaccg cgctattgat
    48361 atgcacattt ccaacctgcg tcgtaaactg ccggatcgta aagatggtca cccgtggttt
    48421 aaaaccttgc gtggtcgcgg ctatctgatg gtttctgctt catgataggc agcttaaccg
    48481 cgcgcatctt cgccatcttc tggctgacgc tggcgctggt gttgatgttg gttttgatgt
    48541 tacccaagct cgattcacgc cagatgaccg agcttctgga tagcgaacag cgtcaggggc
    48601 tgatgattga gcagcatgtc gaagcggagc tggcgaacga tccgcccaac gatttaatgt
    48661 ggtggcggcg tctgttccgg gcgattgata agtgggcacc gccaggacag cgtttgttat
    48721 tggtgaccac cgaaggccgc gtgatcggcg ctgaacgcag cgaaatgcag atcattcgta
    48781 actttattgg tcaggccgat aacgccgatc atccgcagaa gaaaaagtat ggccgcgtgg
    48841 aactggtcgg tccgttctcc gtgcgtgatg gcgaagataa ttaccaactt tatctgattc
    48901 gtccggccag cagttctcaa tccgatttca ttaacttact gtttgaccgc ccgctattac
    48961 tgctgattgt caccatgttg gtcagtacgc cgctgctgtt gtggttggcc tggagtctgg
    49021 caaaaccggc gcgtaagctg aaaaacgctg ccgatgaagt tgcccaggga aacttacgcc
    49081 agcacccgga actggaagcg gggccacagg aattccttgc cgcaggtgcc agttttaacc
    49141 agatggtcac cgcgctggag cgcatgatga cctctcagca gcgtctgctt tctgatatct
    49201 ctcacgagct gcgcaccccg ctgacgcgtc tgcaactggg tacggcgtta ctgcgccgtc
    49261 gtagcggtga aagcaaggaa ctggagcgta ttgaaaccga agcgcaacgt ctggacagca
    49321 tgatcaacga tctgttggtg atgtcacgta atcagcaaaa aaacgcgctg gttagcgaaa
    49381 ccatcaaagc caaccagttg tggagtgaag tgctggataa cgcggcgttc gaagccgagc
    49441 aaatgggcaa gtcgttgaca gttaacttcc cgcctgggcc gtggccgctg tacggcaatc
    49501 cgaacgccct ggaaagtgcg ctggaaaaca ttgttcgtaa tgctctgcgt tattcccata
    49561 cgaagattga agtgggcttt gcggtagata aagacggtat caccattacg gtggacgacg
    49621 atggtcctgg cgttagcccg gaagatcgcg aacagatttt ccgtccgttc tatcgtaccg
    49681 atgaagcacg cgatcgtgaa tctggcggta caggtttggg gctggcgatt gttgaaaccg
    49741 ccattcagca gcatcgtggc tgggtgaagg cagaagacag cccgctgggc ggtttacggc
    49801 tggtgatttg gttgccgctg tataagcgga gttaaacttc gcatttgcag gcaggataag
    49861 gcgtttacgc cgcatccggc atttgagcag gatgcctgat gcgacgctga tagcgtctta
    49921 tcaggcctac actccggggg ttattttccc cacaaccggc gggaaaaatc ttcgatcttg
    49981 ccgctcagtc ggcgcttttg catcgtccgc gtccagcttt tcgataaccc ggcagcggag
    50041 agtaaacggt gatattgatc gtcatcaaac ggcatatgcc atgcgatggc ggcagcctcc
    50101 tgcacggtca catcgctgac acgggaaacc aactccagcg gcgcgtccgc agacactttc
    50161 cctggcgcta tcacgctata caaccacccc accttacctg tgttttgcat caactgcgct
    50221 atatcgctga tatcaaaatg gtaattgagt ttatagcaag gcgagcgcgg ctggctgacc
    50281 tgaattaatg cctctcccca gcggaaaata tcgcccatat aaacattact ttccgtcagg
    50341 ccgtcggttg agaggttttc accaaacgca ggcgcaacaa acaactccgc ctgttccgga
    50401 aattcccgcg cccagtagag ataatgctca cgaggataat gacacagcgc tctgtctggc
    50461 ccgccgtgaa cctttttctc cgcctgctcg tcaccttcca gccccagctc cgtcagcatc
    50521 aactcaccat caacctggat tttagcaatt gcgctgggtt tgccttcggg ataagcctga
    50581 atcttgcctg tgtatacatc aaccggatat cgcatctgtt ccctctccac gagaaatttc
    50641 cccattagac catatttatt ttatgtcagg cgtgctgttt tcgcggtaag tatccaggca
    50701 ggaactcaat agcaaaccgg acgaacgtta gttcatccgg ctgtggggat taaggaagca
    50761 ggtttatttc accgtaccta aaatttcgat tttcgctgct ctggctttga ctttacgtga
    50821 ccagatagag gtaagaattg gcaccagaat cgaagtcaca atgaccgccg tcgctaccag
    50881 cgaagttgct gccggagcca tcggtttaaa cgcaggcacc atttctgcaa tcagcacagg
    50941 tgtcgctacc gcggcccctg cggaactgga agcggcaatt ccggcagtgc catcgccacc
    51001 gccaatcaat ttatcggcga taatcaacgg aataccggtc acgataatta ctgccacacc
    51061 caacaggatc cccagcaaac cagtctgggc aatcacagtc aaatcaatgg tattgcccag
    51121 cgcgaaggca aagaatggaa tcagcgtttg caccgctttg ctgaaaaatt ctcgcaattc
    51181 agggtcaagg ttccccaggg caaagcccac caggaacggt aatactgcgc cgacgaaaac
    51241 atgcggttca aacgaggcaa tcccggcagt gcccagaata atcatcgtca tgagcggccc
    51301 ggactccaac gacatcaaca caaatgcccc agcttcttct tttgtgccgt actgctgcat
    51361 gatggaagcg taaagtccgc cattggtcat atccatcgcc gccaccagcg ccagcgttga
    51421 aagtccggca aagaatccaa cttcaacacc atgttccgga ataatacgcg aggcaattgc
    51481 cgcaaccacc cacgcgacgg caattttagt taccaccagc gtaccggatt tacgcagtac
    51541 cgttcccgtc gcgcttaatt ttattgacgc ccccatgcaa aaaaaccaca ccgccagaat
    51601 gggcaccgta ccggtaatca tcccgttggt gaatgatcca aaatatttcc ccgcccccgg
    51661 cgagaaggtg tggcacagtg cgccaaggaa tagcgggacg agcatcatcc cccccgggat
    51721 tttctcaatc gagcgtttta tctgcatttc catcacctgt cggcatattt ttaagggctg
    51781 atgcgtaatt cctcaatgga gcatcagtgt tgatggaaac gaagatagac attcatttaa
    51841 tcaataaaag tgatcaaaac cacatcaatt gaaacgctgt tttattttta tcggatcatt
    51901 gtttttattt tgaaattgat cacaaaaaaa ccaccgccgt tggcgatggt tcatttttta
    51961 agctgatatg cggcctatac gcctcattgc agcaggcggc aaatgattat tttttcgccg
    52021 caaaacgtgc cgctgcttcg tcccagttca ccacgttcca gaactcttta atgtagtccg
    52081 gacggcggtt ctggaatttc aggtagtaag catgttccca cacatccagg cccataatcg
    52141 ggaagccgga agcgccagaa atagcttcac ccatcagcgg agaatcctgg ttagcagtag
    52201 aaaccaccgc cagtttatcg cctttcagca ccagccatgc ccagccggaa ccaaagcggg
    52261 aagctgccgc tttttcaaat tctgctttga agttatcaac ggagccgaag tcacgttcga
    52321 tagccgcttt caggtcaccc tgcagggtgg tgcctttttt cagacctttc cagaacaggc
    52381 tgtggttagc gtgaccgcca gcgttgttgc gcagtacggt tttcttgtct gctggcagct
    52441 ggtccagttt ggtgatcagc tcttcaaccg gcaggttggc aaattctggc aggctttcca
    52501 gcgccgcgtt ggcgttgttt acgtaggtct gatggtgttt ggtgtggtgg atttccatgg
    52561 tctgcttatc gaagtgcggt tccagggcat cgtaagcata cggcagggat ggcagggtat
    52621 agctcatatt catctccagt attgtcgggc ggccgattgt taatgccgcg taagcagttg
    52681 gttcattata gttaattaaa tgatattgaa aatgattatc aatgccgtac ttttcgtaag
    52741 ggtatggttt tgcaggaaaa tgcccgagat gtgaagcaaa tcacccactt aatgccgtga
    52801 ttgccagtaa atcgacaacg gcggcaacag gcgaaaggtt aatcgacagc acgattttta
    52861 cactcatctc gtcggagatg tgacgcgacg aaaaatgatg aggataagaa gatgagtaac
    52921 gcgattacga tggggatatt ttggcatttg atcggcgcgg ccagtgcagc ctgtttttac
    52981 gctccgttca aaaaagtaaa aaaatggtca tgggaaacca tgtggtcagt cggtgggatt
    53041 gtttcgtgga ttattctgcc gtgggccatc agcgccctgt tactaccgaa tttctgggcg
    53101 tattacagct cgtttagtct ctctacgcta ctgcctgttt ttctgttcgg cgctatgtgg
    53161 gggatcggta atatcaacta cggcctgacc atgcgttatc tcggcatgtc gatgggaatt
    53221 ggcatcgcca ttggcattac gttgattgtc ggtacgctga tgacgccaat tatcaacggc
    53281 aatttcgatg tgttgattag caccgaaggc ggacgcatga cgttgctcgg cgttctggtg
    53341 gcgctgattg gcgtagggat tgtaactcgc gccgggcagt tgaaagagcg caagatgggc
    53401 attaaagccg aagagttcaa tctgaaaaaa gggctggtgc tggcggtgat gtgcggcatt
    53461 ttctctgccg ggatgtcctt tgcgatgaac gccgcaaaac cgatgcatga agccgctgcc
    53521 gcacttggcg tcgatccact gtatgtcgct ctgccaagct atgttgtcat catgggcggc
    53581 ggcgcgatca ttaacctcgg tttctgtttt attcgtctgg caaaagtgaa ggatttgtcg
    53641 ctaaaagccg acttctcgct ggcaaaatcg ctgatcattc acaatgtgtt actctcgaca
    53701 ctgggcgggt tgatgtggta tctgcaattc tttttctatg cctggggcca cgcccgcatt
    53761 ccggcgcagt atgactacat cagttggatg ctgcatatga gtttctatgt attgtgcggc
    53821 ggtatcgtcg ggctggtgct gaaagagtgg aacaatgcag gacgccgtcc ggtaacggtg
    53881 ttgagcctcg gttgtgtggt gattattgtc gccgctaaca tcgtcggcat cggcatggcg
    53941 aattaatctt tctgcgaatt gagatgacgc cactggctgg gcgtcatccc ggtttcccgg
    54001 gtaaacacca ccgaaaaata gttactatct tcaaagccac attcggtcga aatatcactg
    54061 attaacaggc ggctatgctg gagaagatat tgcgcatgac acactctgac ctgtcgcaga
    54121 tattgattga tggtcattcc agtctgctgg cgaaattgct gacgcaaaac gcgctcactg
    54181 cacgatgcct catcacaaaa tttatccagc gcaaagggac ttttcaggct agccgccagc
    54241 cgggtaatca gcttatccag caacgtttcg ctggatgttg gcggcaacga atcactggtg
    54301 taacgatggc gattcagcaa catcaccaac tgcccgaaca gcaactcagc catttcgtta
    54361 gcaaacggca catgctgact actttcatgc tcaagctgac cgataacctg ccgcgcctgc
    54421 gccatcccca tgctacctaa gcgccagtgt ggttgccctg cgctggcgtt aaatcccgga
    54481 atcgccccct gccagtcaag attcagcttc agacgctccg ggcaataaat aatattctgc
    54541 aaaaccagat cgttaacgga agcgtaggag tgtttatcgt cagcatgaat gtaaaagaga
    54601 tcgccacggg taatgcgata agggcgatcg ttgagtacat gcaggccatt accgcgccag
    54661 acaatcacca gctcacaaaa atcatgtgta tgttcagcaa agacatcttg cggataacgg
    54721 tcagccacag cgactgcctg ctggtcgctg gcaaaaaaat catctttgag aagttttaac
    54781 tgatgcgcca ccgtggctac ctcggccaga gaacgaagtt gattattcgc aatatggcgt
    54841 acaaatacgt tgagaagatt cgcgttattg cagaaagcca tcccgtccct ggcgaatatc
    54901 acgcggtgac cagttaaact ctcggcgaaa aagcgtcgaa aagtggttac tgtcgctgaa
    54961 tccacagcga taggcgatgt cagtaacgct ggcctcgctg tggcgtagca gatgtcgggc
    55021 tttcatcagt cgcaggcggt tcaggtatcg ctgaggcgtc agtcccgttt gctgcttaag
    55081 ctgccgatgt agcgtacgca gtgaaagaga aaattgatcc gccacggcat cccaattcac
    55141 ctcatcggca aaatggtcct ccagccaggc cagaagcaag ttgagacgtg atgcgctgtt
    55201 ttccaggttc tcctgcaaac tgcttttacg cagcaagagc agtaattgca taaacaagat
    55261 ctcgcgactg gcggtcgagg gtaaatcatt ttccccttcc tgctgttcca tctgtgcaac
    55321 cagctgtcgc acctgctgca atacgctgtg gttaacgcgc cagtgagacg gatactgccc
    55381 atccagctct tgtggcagca actgattcag cccggcgaga aactgaaatc gatccggcga
    55441 gcgatacagc acattggtca gacacagatt atcggtatgt tcatacagat gccgatcatg
    55501 atcgcgtacg aaacagaccg tgccaccggt gatggtatag ggctgcccat taaacacatg
    55561 aatacccgtg ccatgttcga caatcacaat ttcatgaaaa tcatgatgat gttcaggaaa
    55621 atccgcctgc gggagccggg gttctatcgc cacggacgcg ttaccagacg gaaaaaaatc
    55681 cacactatgt aatacggtca tactggcctc ctgatgtcgt caacacggcg aaatagtaat
    55741 cacgaggtca ggttcttacc ttaaattttc gacggaaaac cacgtaaaaa acgtcgattt
    55801 ttcaagatac agcgtgaatt ttcaggaaat gcggtgagca tcacatcacc acaattcagc
    55861 aaattgtgaa catcatcacg ttcatctttc cctggttgcc aatggcccat tttcctgtca
    55921 gtaacgagaa ggtcgcgaat tcaggcgctt tttagactag tcgtaatgaa attcagcagg
    55981 atcacattat gacctttcgc aattgtgtcg ccgtcgatct cggcgcatcc agtgggcgcg
    56041 tgatgctggc gcgttacgag cgtgaatgcc gcagcctgac gctgcgcgaa atccatcgtt
    56101 ttaacaatgg gctgcatagt cagaacggct atgtcacctg ggatgtggat agccttgaaa
    56161 gtgccattcg ccttggatta aacaaggtgt gcgaggaagg gattcgtatc gatagcattg
    56221 ggattgatac ctggggcgtg gactttgtgc tgctcgacca acagggtcag cgtgtgggcc
    56281 tgcccgttgc ttatcgcgat agccgcacca atggcctaat ggcgcaggca caacaacaac
    56341 tcggcaaacg cgatatttat caacgtagcg gcatccagtt tctgcccttc aatacgcttt
    56401 atcagttgcg tgcgctgacg gagcaacaac ctgaacttat tccacacatt gctcacgctc
    56461 tgctgatgcc ggattacttc agttatcgcc tgaccggcaa gatgaactgg gaatatacca
    56521 acgccacgac cacgcaactg gtcaatatca atagcgacga ctgggacgag tcgctactgg
    56581 cgtggagcgg ggccaacaaa gcctggtttg gtcgcccgac gcatccgggt aatgtcatag
    56641 gtcactggat ttgcccgcag ggtaatgaga ttccagtggt cgccgttgcc agccatgata
    56701 ccgccagcgc ggttatcgcc tcgccgttaa acggctcacg tgctgcttat ctctcttctg
    56761 gcacctggtc attgatgggc ttcgaaagcc agacgccatt taccaatgac acggcactgg
    56821 cagccaacat caccaatgaa ggcggggcgg aaggtcgcta tcgggtgctg aaaaatatta
    56881 tgggcttatg gctgcttcag cgagtgcttc aggagcagca aatcaacgat cttccggcgc
    56941 ttatctccgc gacacaggca cttccggctt gccgcttcat tatcaatccc aatgacgatc
    57001 gctttattaa tcctgagacg atgtgcagcg aaattcaggc tgcgtgtcgg gaaacggcgc
    57061 aaccgatccc ggaaagtgat gctgaactgg cgcgctgcat tttcgacagt ctggcgctgc
    57121 tgtatgccga tgtgttgcat gagctggcgc agctgcgcgg tgaagatttc tcgcaactgc
    57181 atattgtcgg cggaggctgc cagaacacgc tgctcaacca gctatgcgcc gatgcctgcg
    57241 gtattcgggt gatcgccggg cctgttgaag cctcgacgct cggcaatatc ggcatccagt
    57301 taatgacgct ggatgaactc aacaatgtgg atgatttccg tcaggtcgtc agcaccaccg
    57361 cgaatctgac cacctttacc cctaatcctg acagtgaaat tgcccactat gtggcgcaga
    57421 ttcactctac acgacagaca aaggagcttt gcgcatgacc actcaactgg aacaggcctg
    57481 ggagctagcg aaacagcgtt tcgcggcggt ggggattgat gtcgaggagg cgctgcgcca
    57541 acttgatcgt ttacccgttt caatgcactg ctggcagggc gatgatgttt ccggttttga
    57601 aaacccggaa ggttcgctga ccggggggat tcaggccaca ggcaattatc cgggcaaagc
    57661 gcgtaatgcc agtgagctac gtgccgatct ggaacaggct atgcggctga ttccggggcc
    57721 gaaacggctt aatttacatg ccatctatct ggaatcagat acgccagtct cgcgcgacca
    57781 gatcaaacca gagcacttca aaaactgggt tgaatgggcg aaagccaatc agctcggtct
    57841 ggattttaac ccctcctgct tttcgcatcc gctaagcgcc gatggcttta cgctttccca
    57901 tgccgacgac agcattcgcc agttctggat tgatcactgc aaagccagcc gtcgcgtttc
    57961 ggcctatttt ggcgagcaac tcggcacacc atcggtgatg aacatctgga tcccggatgg
    58021 tatgaaagat atcaccgttg accgtctcgc cccgcgtcag cgtctgctgg cagcactgga
    58081 tgaggtgatc agcgagaagc taaaccctgc gcaccatatc gacgccgttg agagcaaatt
    58141 gtttggcatt ggcgcagaga gctacacggt tggctccaat gagttttaca tggggtatgc
    58201 caccagccgc cagactgcgc tgtgcctgga cgccgggcac ttccacccga ctgaagtgat
    58261 ttccgacaag atttccgccg ccatgctgta tgtgccgcag ttgctgctgc acgtcagccg
    58321 tccggttcgc tgggacagcg atcacgtagt gctgctggat gatgaaaccc aggcaattgc
    58381 cagtgagatt gtgcgtcacg atctgtttga ccgggtgcat atcggccttg acttcttcga
    58441 tgcctctatc aaccgcattg ccgcgtgggt cattggtaca cgcaatatga aaaaagccct
    58501 gctgcgtgcg ttgctggaac ctaccgctga gctgcgcaag ctggaagcgg cgggcgatta
    58561 cactgcgcgt ctggcactgc tggaagagca gaaatcgttg ccgtggcagg cggtctggga
    58621 aatgtattgc caacgtcacg atacgccagc aggtagcgaa tggctggaga gcgtgcgggc
    58681 ttatgagaaa gaaattttga gtcgccgcgg gtaaacactg ccggatgcgg cgcgagcgcc
    58741 ttatccggcc tacgggtcgg caacagttgt aggcctgata agacgcgaca gcgtcgcatc
    58801 aggcattgat tgccggatgc ggcacaagtg ccttatccgg cctacaggtc ggcaatagtt
    58861 gtaggcctga taagacgcga cagcgtcgca tcaggcattg attgccggat gcggcgcgag
    58921 cgccttatcc ggcctacggg tcgtgcatcc gacaacaccg aatttacagg aacacagaac
    58981 atgcaaaaca ttactcagtc ctggtttgtc cagggaatga tcaaagccac caccgacgcc
    59041 tggctgaaag gctgggatga gcgcaacggc ggcaacctga cgctacgcct ggatgacgcc
    59101 gatatcgcac catatcacga caatttccac caacaaccgc gctatatccc gctcagccag
    59161 cccatgcctt tactggcaaa tacaccgttt attgtcaccg gctcgggcaa attcttccgt
    59221 aacgtccagc ttgatcctgc ggctaactta ggcatcgtaa aagtcgacag cgacggcgcg
    59281 ggctaccaca ttctttgggg gttaaccaac gaagccgtcc ccacttccga acttccggct
    59341 cacttccttt cccactgcga gcgcattaaa gccaccaacg gcaaagatcg ggtgatcatg
    59401 cactgccacg ccaccaacct gatcgccctc acctatgtac ttgaaaacga caccgcggtc
    59461 ttcactcgcc aactgtggga aggcagcacc gagtgtctgg tggtattccc ggatggcgta
    59521 ggcattttgc cgtggatgat gcccggcacg gacgaaatcg gccaggcgac cgcacaagag
    59581 atgcaaaaac attcgctggt gttgtggccc ttccacggcg tcttcggcag cggaccgacg
    59641 ctggatgaaa ccttcggttt aatcgacacc gcagaaaaat cagcacaagt attagtgaag
    59701 gtttattcga tgggcggcat gaaacagacc atcagccgtg aagagttgat agcgctcggc
    59761 aagcgtttcg gcgttacgcc actcgccagt gcgctggcgc tgtaaggagc aaacatgatc
    59821 cgcaaagcct ttgtcatgca ggtaaacccc gacgcccacg aagagtatca gcgtcggcat
    59881 aatcccatct ggccagaact ggaagcagtg ctgaaatctc acggtgcgca taactacgcc
    59941 atctatctcg acaaagcgcg taatctgctg tttgccatgg tagagattga atctgaagaa
    60001 cgctggaatg cggttgccag cactgatgtt tgccaacgtt ggtggaaata tatgaccgat
    60061 gttatgcccg ctaacccgga taacagcccg gtgagtagcg agctgcaaga agtgttttac
    60121 ctgccgtaat tgcccaatgt gccagagatg cctccggcac aatattttaa atttcgattt
    60181 gaaaaattaa acatattaca tctcccggta agttatattt ccctgataca ttgtgagtaa
    60241 atcacaaaaa taatgaataa cccattaatg attcatgtgg tttatttaaa taaccattat
    60301 gtgcattact ccgcaaatct gacctttcac tctgtctcaa attgtcattg tttaccgaca
    60361 tatcgcctct catcacttaa tcgctccacc attacaattg attaaaatat attttatgga
    60421 gtccgattaa tggcagctct tactgcaagc tgtattgacc tgaatattca gggcaatggc
    60481 gcttattccg ttctgaagca gttggcgaca atagcgttac aaaacggttt tatcaccgac
    60541 tcacaccagt tcctgcaaac cctgctgctg cgcgaaaaaa tgcactctac tggatttggt
    60601 tccggtgtcg ccgtgccgca cggtaaaagc gcctgcgtta aacaaccgtt cgtattattc
    60661 gcccgcaaag cgcaggctat tgactggaaa gccagcgatg gcgaagacgt caattgctgg
    60721 atctgcctcg gcgtgccgca aagcggcgaa gaggatcagg tcaaaatcat cggcacactg
    60781 tgtcgcaaaa ttattcacaa ggaatttatt catcaactgc aacagggcga taccgaccag
    60841 gtgcttgcct tgttaaatca aaccctcagc tcataaggaa gtggcgatgg agtcatcctt
    60901 acgtattgtc gcgatcacca actgccccgc cgggatcgct cacacctaca tggtggcgga
    60961 agccctggaa cagaaagccc gttctctcgg tcataccata aaagtggaaa ctcaagggtc
    61021 cagtggcgtt gaaaaccgct tatccagcga agagattgcc gctgccgatt acgtcattct
    61081 cgctaccggg cgtggcctga gcggtgatga tcgcgcgcgg tttgccggga agaaagttta
    61141 tgagattgcc atctcccagg cgttgaaaaa tatcgaccag attttcagcg aattaccgac
    61201 aaactcgcag ctttttgccg cagatagcgg cgtgaagctt ggcaaacagg aagtgcaaag
    61261 cggtagcgtg atgagccacc tgatagcggg cgtctctgcg gcgctgccgt ttgtcatcgg
    61321 cggtggtatc ctggtggcgc ttgccaacat gctggtgcag ttcggtttgc cgtataccga
    61381 tatgtcgaaa ggcgcgccgt cgtttacctg ggtagttgaa tccatcggtt accttggctt
    61441 cacctttatg atccccatca tgggcgctta tattgcctcg tcgattgccg ataaaccggc
    61501 tttcgctccg gcgtttctgg tttgctatct ggcgaacgac aaagcgctgc tcggcaccca
    61561 gtcgggtgcg ggattcctcg gcgcggtggt gctggggctg gcgattggct atttcgtctt
    61621 ctggttccgc aaagtgcgcc ttggcaaagc attacaaccg ctgctcggtt caatgctgat
    61681 cccgttcgtt actctgctgg ttttcggcgt gctcacttac tacgttatcg ggccggtgat
    61741 gtccgacctc atgggcgggc tgctccactt cctgaatacc attcctccat caatgaagtt
    61801 tgcggcagcg tttctggtcg gtgcgatgct ggcgttcgat atgggcggcc ccatcaataa
    61861 aaccgcctgg ttcttctgct tctcactgct ggaaaaacac atttatgact ggtacgccat
    61921 cgtcggcgtt gtcgcgctga tgccgcccgt cgcggcgggt cttgcgacgt tcattgcgcc
    61981 caaactgttt acccgacagg aaaaagaggc tgccagtagt gccattgtgg tcggtgccac
    62041 agtcgcaacc gaaccggcta ttccttacgc tctggcagct ccgttgccga tgattaccgc
    62101 caatacgctg gcgggcggca ttaccggcgt gctggtgatc gctttcggaa tcaaacgtct
    62161 ggcacctggt ttgggtatct ttgacccgct gatcggcctg atgtcgccgg tgggttcgtt
    62221 ttatctggtg ctggcgattg gcctcgcgct gaacatttca ttcattatcg tcctgaaagg
    62281 attgtggtta cgccgcaaag cgaaagccgc gcaacaggag cttgtccatg aacattgagt
    62341 tactgcaaca gttgtgcgaa gccagcgccg tcagcggcga tgaacaggaa gttcgcgaca
    62401 ttctgataaa cacgctggaa ccttgcgtga atgaaatcac cttcgatggt ctgggcagct
    62461 ttgttgcccg taaggggaat aaaggtccaa aagttgccgt tgtcggacat atggatgaag
    62521 tcggctttat ggtcacccac atcgacgaga gcggttttct gcgttttacc accattggcg
    62581 gctggtggaa tcagtcgatg ctcaaccacc gggtaaccat acgcacacac aagggagtga
    62641 aaatccctgg tgtgattggt tccgtcgcgc ctcatgcgtt aacggaaaag caaaagcaac
    62701 aaccgctgtc atttgatgag atgttcattg atattggcgc gaacagtcgc gaagaggtgg
    62761 aaaagcgcgg cgtggaaatt ggtaatttta ttagcccgga agccaatttt gcctgctggg
    62821 gcgaagataa agtggtcggc aaggcgttgg ataaccgcat cggctgcgca atgatggctg
    62881 aactattgca gacggtgaat aatcccgaaa ttacgctgta tggcgttggc agtgtggaag
    62941 aagaagttgg gctacgcggg gcgcaaacct cggcggaaca cattaaaccg gacgtcgtga
    63001 tcgtgttgga taccgccgta gcgggcgatg ttccgggcat tgataacatt aaatacccgc
    63061 tgaaactggg ccaggggccg gggctgatgc tgtttgacaa gcgctacttc cccaaccaga
    63121 aactggtagc agtgttaaaa agctgtgccg cacataacga tttaccgctg caattttcca
    63181 ccatgaaaac cggtgcgacg gatggcgggc gctacaacgt gatgggcggc gggcgtccgg
    63241 ttgtcgcgct gtgtctgcca actcgttatc tgcacgccaa cagcggtatg atttcaaaag
    63301 ccgattacga agctctgctc acgctgatac ggggttttct gacgacctta actgcggaga
    63361 aagtcaacgc gtttagccag ttccgtcagg tggattaatg ctaaacgaac gccagttaaa
    63421 gattgtcgat ctgctggagc aacagccgcg cacgcctggc gagctggcgc aacagactgg
    63481 cgtttcaggc aggaccatcc tgcgtgatat tgactatctc aacttcaccc ttaacggcaa
    63541 agcccgcatt ttcgccagtg gcagtgcggg ctatcagctg gaaatcttcg agcgccgcag
    63601 cttttttcag ttgctgcaaa agcacgataa cgacgatcgg ctgctggcgc tgttattact
    63661 gaatactttc actccccgtg cgcaactcgc ctcggcgctt aatttgccag aaacgtgggt
    63721 agcagagcgt ctgccccggt taaaacagcg ttatgaacgc acttgttgcc tggccagccg
    63781 ccctggtttg ggccatttca ttgatgagac agaagagaaa cgcgttatct tgctggcgaa
    63841 cttgctgcgc aaagatccgt ttttaattcc gctggcgggc ataacacgag acaaccttca
    63901 gcatttatcc acggcctgcg acaaccaaca ccgctggccg ctcatgcagg gtgattatct
    63961 ctccagcctg attctggcga tttacgccct gcgtaatcaa ctgaccgatg agtggccgca
    64021 atatcccggt gacgagataa aacaaatcgt tgaacatagc ggtctgtttc ttggtgataa
    64081 cgctgtaaga accctgacgg gtttgataga gaaacagcat cagcaagcgc aggtaatttc
    64141 agccgataat gtgcaggggt tgctgcaaag ggtgccgggc atcgcgtcat tgaatattat
    64201 tgatgcgcag ctggttgaga atattaccgg gcatttatta cgttgccttg ccgcaccagt
    64261 gtggattgct gagcaccgcc agagcagcat gaataacctg aaagccgcct ggcctgcggc
    64321 ctttgatatg agtctgcact ttattacgct actgcgtgaa cagctcgata ttcccctttt
    64381 cgacagcgat ctgatcggtt tgtattttgc ctgtgcgctg gagcggcatc aaaacgaacg
    64441 ccagccgatc attttgctct cggaccagaa cgcgattgcc actattaatc agctcgccat
    64501 tgagcgcgat gttttaaatt gtcgggtaat tattgcccgt agcttaagcg aacttgttgc
    64561 cattcgcgaa gagattgagc cgttattgat cattaacaac agccattatt tactggatga
    64621 cgcggtaaat aattacatca ccgtaaaaaa tatcattacg gctgccggta tcgaacaaat
    64681 aaaacatttt ctggcgacgg catttattcg ccaacagccg gagcgttttt tctctgcccc
    64741 cggaagtttt cattattcga atgtacgcgg tgaaagctgg caacatatta cccggcaaat
    64801 ttgtgcgcaa ttagtcgcac aacaccatat taccgccgat gaagcacaac gcatcatcgc
    64861 ccgcgaaggc gaaggtgaaa acctgattgt taatcgcctc gccatcccac attgctggag
    64921 cgaacaggag cgacgttttc gtggattttt tattaccctc gcccaaccag ttgaggtgaa
    64981 taacgaagtc attaaccatg tcttgatcgc ctgcgccgcc gccgatgcgc gtcatgagct
    65041 aaaaatattt agctatctgg caagcatatt gtgtcagcat ccggcggaga ttattgccgg
    65101 gttaacagga tatgaggcat ttatggagtt acttcacaag gggtgaactg tgtcggatgc
    65161 gccgcatccg acactgcatt tatcatcaaa aacgtttaac gcaggctatt atagtcatca
    65221 accatttcgt tgtactcgcg taatgctctc gggaaagagt cttcgaccat ccagcttgag
    65281 tttgcgtcct gaagttgctc tttatcccag tcagagtacg ggactttatc tctgatgcgg
    65341 cgaacgtatt ttttagcctc gagttgatac tggcctgccg aattaataaa cgagaaattc
    65401 atgccgcctt tatccgcttc tttggcctgc gccactagcg tttccagttc agacactttc
    65461 ttcattgccg cttctgcatc aaacttatct tgcgatatca ggttattaat ttgtttcgct
    65521 gaaatcatga ctgccagaga gtagtagtgg aatgttttcc cttctctttc ttcaatattt
    65581 ttcagttccg caagctgacg cttatcatta atttcctgaa tcgccgcatg ataagattcg
    65641 gctacaggtt caaaggcttc cagatttttt aagaatgtct ggtgcagcgt tttccctttc
    65701 gcaaacgcat cgtctttata attttcctgg gtgtaatatt tatccatttc gttaatggta
    65761 ttacccaacg ccacggcagc atcgatataa ctcaccgcca cgccatcaat tggttgcagc
    65821 gcaggcgtta acgccacagc actttttacg cctttttcac actcagcgag gttggattca
    65881 ctaatgccgt agatgccata aacagtacgc tcttcaccgg taggcccctg tttaaaatct
    65941 ttcagccagt cagcataacg cgccagactg cgctgtaccg ggatctgtaa cttgttgtag
    66001 cacttgatat agacatccat tttttcgtcg aaaaccgctt gttcatcgac caccggttgc
    66061 gcaggtgttt caggtttagc ttctgctttt gcaacgggag cttcagtagg tttcgcttca
    66121 ggagctggtg cggcaggttg actattggca ggcgggagcg tttctgtttc ggctttttta
    66181 tcatcacaac ccgtcagacc gagggacatg atggcgacta taatagcgga agataataaa
    66241 ttccttttca tttaattgcc ttataaatat atagataaga gagtgaacat aataaatgaa
    66301 aaaag
//
LOCUS       DACAOP010000015        66246 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.015, whole genome shotgun sequence.
ACCESSION   DACAOP010000015 DACAOP010000000
VERSION     DACAOP010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 66246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66246
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.015"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..449)
                     /gene="folK"
                     /locus_tag="IT892_001086"
     CDS             complement(<1..449)
                     /gene="folK"
                     /locus_tag="IT892_001086"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HAP3134325.1"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTP
                     PLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGEMLRQILHT"
     gene            complement(446..1864)
                     /gene="pcnB"
                     /locus_tag="IT892_001087"
     CDS             complement(446..1864)
                     /gene="pcnB"
                     /locus_tag="IT892_001087"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HAP3134326.1"
                     /translation="MTLPRCTIFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQH
                     AISRKDISENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKL
                     FRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGS
                     IEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLR
                     AVRFAAKLGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEY
                     HLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLL
                     ETAQKIAQESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQG
                     KRAWKLLEHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDE
                     EPSPRRRTRRPRKRAPRREGTA"
     gene            complement(1903..2829)
                     /gene="gluQRS"
                     /locus_tag="IT892_001088"
     CDS             complement(1903..2829)
                     /gene="gluQRS"
                     /locus_tag="IT892_001088"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414686.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HAP3134327.1"
                     /translation="MLPPYFLFKEMTDTQYIGRFAPSPSGELHFGSLIAALGSYLQAR
                     ARQGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHDAYREALAWL
                     HEQGLSYYCTCTRARIQSIGGIYDGHCRVLHHGPDNAAVRIRQQHPVTQFTDQLRGII
                     HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQISLYQLF
                     GWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALQFLGQQAEAHWQDFS
                     VEQILQSAVKNWRLTAVPESAIVNSTFSNASC"
     gene            complement(2866..3321)
                     /locus_tag="IT892_001089"
     CDS             complement(2866..3321)
                     /locus_tag="IT892_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding transcription factor
                     DksA"
                     /protein_id="HAP3134328.1"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     gene            complement(3499..4203)
                     /gene="sfsA"
                     /locus_tag="IT892_001090"
     CDS             complement(3499..4203)
                     /gene="sfsA"
                     /locus_tag="IT892_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAP3134329.1"
                     /translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICVNTLWANRLTKEAILNESISELS
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     ISAEGMALKKSLPVTL"
     gene            complement(4218..4748)
                     /gene="thpR"
                     /locus_tag="IT892_001091"
     CDS             complement(4218..4748)
                     /gene="thpR"
                     /locus_tag="IT892_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HAP3134330.1"
                     /translation="MSEPQRLFFAIDLPAEIREQIIHWRATHFPPEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYAVTEFTLYASSFA
                     RGRTRYTPLKRWALTQ"
     gene            4822..7251
                     /gene="hrpB"
                     /locus_tag="IT892_001092"
     CDS             4822..7251
                     /gene="hrpB"
                     /locus_tag="IT892_001092"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HAP3134331.1"
                     /translation="MSSLPVAAVLPELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAH
                     PGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEG
                     VLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD
                     NDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRFDDAVAVATAEMLRQESGSLLLF
                     LPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE
                     TSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRLEPGISLH
                     LIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPVVNLLAAKRL
                     LQMLGALEGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMG
                     NSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDG
                     RYQLANGMGAMLDANDALSRHEWLIAPLLLQGSASPDARILLALLVDIDELVQRCPQL
                     VQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIRDKGLSVL
                     NWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLAALETWLLPHMTGVHSLRGLKSLD
                     IYQALRGLLDWGMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATN
                     PTIAQGRVPLVLELLSPAQRPLQITRDLSAFWKGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
     gene            7447..9981
                     /gene="mrcB"
                     /locus_tag="IT892_001093"
     CDS             7447..9981
                     /gene="mrcB"
                     /locus_tag="IT892_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glycosyl
                     transferase/transpeptidase"
                     /protein_id="HAP3134332.1"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRILPVWTSDPQSLCQQSE
                     MQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN"
     gene            10201..12444
                     /gene="fhuA"
                     /locus_tag="IT892_001094"
     CDS             10201..12444
                     /gene="fhuA"
                     /locus_tag="IT892_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome porin FhuA"
                     /protein_id="HAP3134333.1"
                     /translation="MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
                     TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
                     LSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
                     RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLD
                     DDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLR
                     FAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDT
                     QLQSKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLNLYNPVNTDFDFNAKDP
                     ANSGPYRILNKQKQTGVYVQDQAQWDKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQ
                     FTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKYVPEDRP
                     IVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYT
                     DAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANS
                     FKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVV
                     ATATFRF"
     gene            12495..13292
                     /gene="fhuC"
                     /locus_tag="IT892_001095"
     CDS             12495..13292
                     /gene="fhuC"
                     /locus_tag="IT892_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC"
                     /protein_id="HAP3134334.1"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     gene            13292..14182
                     /gene="fhuD"
                     /locus_tag="IT892_001096"
     CDS             13292..14182
                     /gene="fhuD"
                     /locus_tag="IT892_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD"
                     /protein_id="HAP3134335.1"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYED
                     FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRVLDNAIGGKA"
     gene            14179..16161
                     /gene="fhuB"
                     /locus_tag="IT892_001097"
     CDS             14179..16161
                     /gene="fhuB"
                     /locus_tag="IT892_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter permease
                     FhuB"
                     /protein_id="HAP3134336.1"
                     /translation="MSKRIALFPALLLALLVIVATALTWMNFSQALPRSQWAQAAWSP
                     DIDVIEQMIFHYSLLPRLVISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDRVAAERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPAGSLGAAVTLLIIMIAAGRSGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
     gene            complement(16319..17599)
                     /gene="hemL"
                     /locus_tag="IT892_001098"
     CDS             complement(16319..17599)
                     /gene="hemL"
                     /locus_tag="IT892_001098"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HAP3134337.1"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
                     LLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     gene            17824..19245
                     /gene="clcA"
                     /locus_tag="IT892_001099"
     CDS             17824..19245
                     /gene="clcA"
                     /locus_tag="IT892_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="HAP3134338.1"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYSLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASASENT"
     gene            19269..19334
                     /locus_tag="IT892_001100"
     CDS             19269..19334
                     /locus_tag="IT892_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134339.1"
                     /translation="MAIIIGLEFAQLPMSFGAKYE"
     gene            19327..19671
                     /gene="erpA"
                     /locus_tag="IT892_001101"
     CDS             19327..19671
                     /gene="erpA"
                     /locus_tag="IT892_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HAP3134340.1"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     gene            complement(19718..20341)
                     /locus_tag="IT892_001102"
     CDS             complement(19718..20341)
                     /locus_tag="IT892_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRIC cation channel family protein"
                     /protein_id="HAP3134341.1"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     gene            complement(20379..21179)
                     /gene="btuF"
                     /locus_tag="IT892_001103"
     CDS             complement(20379..21179)
                     /gene="btuF"
                     /locus_tag="IT892_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter substrate-binding
                     protein BtuF"
                     /protein_id="HAP3134342.1"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     gene            complement(21172..21870)
                     /gene="mtnN"
                     /locus_tag="IT892_001104"
     CDS             complement(21172..21870)
                     /gene="mtnN"
                     /locus_tag="IT892_001104"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAP3134343.1"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     gene            21954..23471
                     /gene="dgt"
                     /locus_tag="IT892_001105"
     CDS             21954..23471
                     /gene="dgt"
                     /locus_tag="IT892_001105"
                     /EC_number="3.1.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dGTPase"
                     /protein_id="HAP3134344.1"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAAL
                     RLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     gene            23601..25025
                     /gene="degP"
                     /locus_tag="IT892_001106"
     CDS             23601..25025
                     /gene="degP"
                     /locus_tag="IT892_001106"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegP"
                     /protein_id="HAP3134345.1"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSSS
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSTIYLLMQ"
     gene            25180..26337
                     /locus_tag="IT892_001107"
     CDS             25180..26337
                     /locus_tag="IT892_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414704.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family transcriptional regulator"
                     /protein_id="HAP3134346.1"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
                     NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQ
                     RMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKTMDNNGLLRRTLAAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
     gene            complement(26426..26812)
                     /locus_tag="IT892_001108"
     CDS             complement(26426..26812)
                     /locus_tag="IT892_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3461 family protein"
                     /protein_id="HAP3134347.1"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     gene            complement(26974..27786)
                     /gene="yaeI"
                     /locus_tag="IT892_001109"
     CDS             complement(26974..27786)
                     /gene="yaeI"
                     /locus_tag="IT892_001109"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414706.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase YaeI"
                     /protein_id="HAP3134348.1"
                     /translation="MISRRRFLQATAATIATSSGFGYMHYCEPGWFELIRHRLAFFKD
                     NAAPFKILFLADLHYSRFVPLSLISDAIALGIEQKPDLILLGGDYVLFDMSLNFSAFS
                     DVLSPLAECAPTFACFGNHDRPVGTEKNHLIGETLKSAGITVLFNQATVIATPNRQFE
                     LVGTGDLWAGQCKPPPASEANLPRLVLAHNPDSKEVMRDEPWDLMLCGHTHGGQLRVP
                     LVGEPFAPVEDKRYVAGLNAFGERHIYTTRGVGSLYGLRLNCRPEVTMLELV"
     gene            complement(27840..28664)
                     /gene="dapD"
                     /locus_tag="IT892_001110"
     CDS             complement(27840..28664)
                     /gene="dapD"
                     /locus_tag="IT892_001110"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HAP3134349.1"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     gene            complement(28695..31367)
                     /gene="glnD"
                     /locus_tag="IT892_001111"
     CDS             complement(28695..31367)
                     /gene="glnD"
                     /locus_tag="IT892_001111"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     uridylyltransferase/uridylyl-removing protein GlnD"
                     /protein_id="HAP3134350.1"
                     /translation="MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQ
                     RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDVDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVHNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGNPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
     gene            complement(31429..32223)
                     /gene="map"
                     /locus_tag="IT892_001112"
     CDS             complement(31429..32223)
                     /gene="map"
                     /locus_tag="IT892_001112"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAP3134351.1"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
     gene            32591..33316
                     /gene="rpsB"
                     /locus_tag="IT892_001113"
     CDS             32591..33316
                     /gene="rpsB"
                     /locus_tag="IT892_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAP3134352.1"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     gene            33574..34425
                     /gene="tsf"
                     /locus_tag="IT892_001114"
     CDS             33574..34425
                     /gene="tsf"
                     /locus_tag="IT892_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAP3134353.1"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     gene            34572..35297
                     /gene="pyrH"
                     /locus_tag="IT892_001115"
     CDS             34572..35297
                     /gene="pyrH"
                     /locus_tag="IT892_001115"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAP3134354.1"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     gene            35589..36146
                     /gene="frr"
                     /locus_tag="IT892_001116"
     CDS             35589..36146
                     /gene="frr"
                     /locus_tag="IT892_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAP3134355.1"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     gene            36238..37434
                     /gene="ispC"
                     /locus_tag="IT892_001117"
     CDS             36238..37434
                     /gene="ispC"
                     /locus_tag="IT892_001117"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HAP3134356.1"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
                     VMRLAS"
     gene            37623..38381
                     /gene="ispU"
                     /locus_tag="IT892_001118"
                     /gene_synonym="uppS"
     CDS             37623..38381
                     /gene="ispU"
                     /locus_tag="IT892_001118"
                     /gene_synonym="uppS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /protein_id="HAP3134357.1"
                     /translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
                     VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     gene            38394..39251
                     /gene="cdsA"
                     /locus_tag="IT892_001119"
     CDS             38394..39251
                     /gene="cdsA"
                     /locus_tag="IT892_001119"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414717.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAP3134358.1"
                     /translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
                     QLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
                     VLFYPGSAAIWRNSKTLRLIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLDVAPV
                     TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     gene            39263..40615
                     /gene="rseP"
                     /locus_tag="IT892_001120"
     CDS             39263..40615
                     /gene="rseP"
                     /locus_tag="IT892_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma E protease regulator RseP"
                     /protein_id="HAP3134359.1"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     gene            40645..43077
                     /gene="bamA"
                     /locus_tag="IT892_001121"
     CDS             40645..43077
                     /gene="bamA"
                     /locus_tag="IT892_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HAP3134360.1"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     gene            43199..43684
                     /gene="skp"
                     /locus_tag="IT892_001122"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
     CDS             43199..43684
                     /gene="skp"
                     /locus_tag="IT892_001122"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Skp"
                     /protein_id="HAP3134361.1"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     gene            43688..44713
                     /gene="lpxD"
                     /locus_tag="IT892_001123"
     CDS             43688..44713
                     /gene="lpxD"
                     /locus_tag="IT892_001123"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HAP3134362.1"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     gene            44818..45273
                     /gene="fabZ"
                     /locus_tag="IT892_001124"
     CDS             44818..45273
                     /gene="fabZ"
                     /locus_tag="IT892_001124"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP3134363.1"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     gene            45277..46065
                     /gene="lpxA"
                     /locus_tag="IT892_001125"
     CDS             45277..46065
                     /gene="lpxA"
                     /locus_tag="IT892_001125"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HAP3134364.1"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     gene            46065..47213
                     /gene="lpxB"
                     /locus_tag="IT892_001126"
     CDS             46065..47213
                     /gene="lpxB"
                     /locus_tag="IT892_001126"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HAP3134365.1"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKEHVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     gene            47210..47806
                     /gene="rnhB"
                     /locus_tag="IT892_001127"
     CDS             47210..47806
                     /gene="rnhB"
                     /locus_tag="IT892_001127"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAP3134366.1"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
                     DSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
     gene            47843..51325
                     /gene="dnaE"
                     /locus_tag="IT892_001128"
     CDS             47843..51325
                     /gene="dnaE"
                     /locus_tag="IT892_001128"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAP3134367.1"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLETELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     gene            51338..52297
                     /gene="accA"
                     /locus_tag="IT892_001129"
     CDS             51338..52297
                     /gene="accA"
                     /locus_tag="IT892_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAP3134368.1"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA"
     gene            52396..54537
                     /gene="ldcC"
                     /locus_tag="IT892_001130"
     CDS             52396..54537
                     /gene="ldcC"
                     /locus_tag="IT892_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase LdcC"
                     /protein_id="HAP3134369.1"
                     /translation="MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWF
                     FEYALGQAEDIAIRMRQYTDEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
                     SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTN
                     GTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIP
                     RREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEA
                     FMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWF
                     FDIWQPPQVDEAECWPVAPGEQWHGFNDADADHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRI
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAW
                     QRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSV
                     GQHYPGFETDIHGAKQDEDGVYRVRVLKMAG"
     gene            54594..54983
                     /locus_tag="IT892_001131"
     CDS             54594..54983
                     /locus_tag="IT892_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414729.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP3134370.1"
                     /translation="MLGLKQVHHIAIIATDYAVSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCET
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     gene            55048..56346
                     /gene="tilS"
                     /locus_tag="IT892_001132"
     CDS             55048..56346
                     /gene="tilS"
                     /locus_tag="IT892_001132"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAP3134371.1"
                     /translation="MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGVAL
                     RAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTR
                     GELVQWARQYDLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
                     QESLLDELLADDLAHCQSPQGTLQIVPMLAMSDARRAAIIRRWLAGQNAPMPSRDALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVTGQSENIVPWQTWLQPLELPA
                     GLGSVQLNAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGVFVTQEGVAEGENGVSFVWQKTLS"
     gene            complement(56395..56655)
                     /gene="rof"
                     /locus_tag="IT892_001133"
     CDS             complement(56395..56655)
                     /gene="rof"
                     /locus_tag="IT892_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho-binding antiterminator"
                     /protein_id="HAP3134372.1"
                     /translation="MSMNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASD
                     LVSRKNVEYLVVEAAGETRELRLDKITSFSHPEIGTVVVSES"
     gene            complement(56642..56842)
                     /locus_tag="IT892_001134"
     CDS             complement(56642..56842)
                     /locus_tag="IT892_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeP family protein"
                     /protein_id="HAP3134373.1"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNE"
     gene            57008..57553
                     /locus_tag="IT892_001135"
     CDS             57008..57553
                     /locus_tag="IT892_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HAP3134374.1"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFTYNSRAAQIWWQQNQSKCVQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGV
                     IWLSDDKNNLEVNLTAWQQPS"
     gene            57550..57972
                     /gene="arfB"
                     /locus_tag="IT892_001136"
     CDS             57550..57972
                     /gene="arfB"
                     /locus_tag="IT892_001136"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAP3134375.1"
                     /translation="MIVISRHVAIPDGELEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAMIKELTTEK
                     KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
     gene            57986..58696
                     /gene="nlpE"
                     /locus_tag="IT892_001137"
                     /gene_synonym="cutF"
     CDS             57986..58696
                     /gene="nlpE"
                     /locus_tag="IT892_001137"
                     /gene_synonym="cutF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414734.1"
                     /note="NlpE, an outer membrane lipoprotein, interacts
                     directly with CpxA, the sensor histidine kinase of the Cpx
                     system for response to envelope stress; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /protein_id="HAP3134376.1"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEAAQSSLPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERSYLAARGHSEKPVLLSVEGHFTLEGNPDTGAPTKVLA
                     PDTAGKFYPNQDCSSLGQ"
     gene            complement(58896..59720)
                     /locus_tag="IT892_001138"
     CDS             complement(58896..59720)
                     /locus_tag="IT892_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414735.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeF family permuted papain-like enzyme"
                     /protein_id="HAP3134377.1"
                     /translation="MDKPKAYCRLFLPSFLLLSACTVDISQPDPSATAVDAEAKTWAV
                     KFQHQSSFTEQSIKEITAPDLKPGDLLFSSSLGVTSFGIRVFSTSSVSHVAIFLGDNN
                     VAEATGAGVQIVSLKKAMKHSDKLFVLRVPDLTPQQATDITAFANKIKDSGYNYRGIV
                     EFIPFMVTRQMCSLNPFSEDFRQQCVSGLAKAQLSSVGEGDKKSWFCSEFVTDAFAKA
                     GHPLTLAQSGWISPADLMHMRIGDVSAFKPETQLQYVGHLKPGIYIKAGRFVGLTR"
     gene            complement(59774..61492)
                     /gene="proS"
                     /locus_tag="IT892_001139"
     CDS             complement(59774..61492)
                     /gene="proS"
                     /locus_tag="IT892_001139"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAP3134378.1"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYL
                     VKQIKG"
     gene            complement(61604..62311)
                     /gene="tsaA"
                     /locus_tag="IT892_001140"
     CDS             complement(61604..62311)
                     /gene="tsaA"
                     /locus_tag="IT892_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HAP3134379.1"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     gene            complement(62308..62712)
                     /gene="rcsF"
                     /locus_tag="IT892_001141"
     CDS             complement(62308..62712)
                     /gene="rcsF"
                     /locus_tag="IT892_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rcs stress response system protein RcsF"
                     /protein_id="HAP3134380.1"
                     /translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
     gene            complement(62830..63645)
                     /gene="metQ"
                     /locus_tag="IT892_001142"
     CDS             complement(62830..63645)
                     /gene="metQ"
                     /locus_tag="IT892_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter substrate-binding
                     lipoprotein MetQ"
                     /protein_id="HAP3134381.1"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKESPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     gene            complement(63685..64338)
                     /gene="metI"
                     /locus_tag="IT892_001143"
     CDS             complement(63685..64338)
                     /gene="metI"
                     /locus_tag="IT892_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease MetI"
                     /protein_id="HAP3134382.1"
                     /translation="MSEPMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIIANAKLYRTVSAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     gene            complement(64331..65362)
                     /gene="metN"
                     /locus_tag="IT892_001144"
     CDS             complement(64331..65362)
                     /gene="metN"
                     /locus_tag="IT892_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein
                     MetN"
                     /protein_id="HAP3134383.1"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEVKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     gene            65550..66125
                     /gene="gmhB"
                     /locus_tag="IT892_001145"
     CDS             65550..66125
                     /gene="gmhB"
                     /locus_tag="IT892_001145"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HAP3134384.1"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLEDMQAAVAANVGTKVLVRTGKP
                     ITPEAENAADWVLNSLADLPQAIKKQQKPAQ"
BASE COUNT        15601 a        16551 c        18265 g        15829 t
ORIGIN      
        1 gtatgtaaga tttgacgcaa catctcccca tcaggaaaca ccaactccgg cgcgatttca
       61 aacagcggcc acagcataaa tccacgattc ttcatatcgt agtgcggaac ggtcaggcgt
      121 tcagtattta tcacttcatt accaaacagc atgatgtcga gatccagcgt gcgtggtccc
      181 cagcgttcag ctttgcggac gcgaccttgc tgcaattcaa tacgctgtgt gtgattgagt
      241 agctcttcag gtgcaagaga ggtttccagc gccacggctg cgtttaagta atcgggttga
      301 tcttgcggcc ccagcggtgg ggtgcggtaa aacgaagaaa cggtaagaat gtggctttca
      361 gggatatcgc ctaatgcttt cagggcagca ttgacctgct ccagcggaga ggccagattg
      421 ctgcctatgg caatatacgc cactgtcatg cggtaccctc acgacgtggt gcgcgtttgc
      481 gtggacgacg agtacgacga cgcggtgacg gttcttcatc cagctcgttg agcatccctt
      541 tttggtctgg tggcgcggaa acctggaact caccccacca tttcaccaga cgctgcagtt
      601 cagcgttacg ctcaacttca gctcgcaagg ccaacaggtc ataagccgca cggaacttag
      661 gatgctccag cagtttccat gcgcgtttac cctgacgacg ggacatacgc aactgcaact
      721 gccagatatc gcgggttaat gtcgtcagac gtttcgggat tgccagtgaa cggcaggctt
      781 cgtccagcac gtcgttcatc gccagcgcga aagcgtcgtg ataggtcagg ccgctttcct
      841 gggcgatctt ctgtgccgtc tccagcagtg ggtaccagaa catggcggca aacaggaacg
      901 ccgggttcac gcgcatatcg ttatggatac gcgtatcggt attcttcagc acctgttcaa
      961 tgatccgctc catcgggctg tcgccatttt ccgtgaagta gcgggtaatg gtcgggaaca
     1021 gcggctggaa cagatgatat tcacacaaca gcttataggt ttcgtaaccg tagcccgctt
     1081 gtagcagttt aagcgattct tcaaacaggc gtgccggtgg gatatcgttc agcagggtag
     1141 cgaggcgagg gatcggttct gcggtttccg ggctgatgcg catacccaat ttggcggcaa
     1201 aacgtaccgc gcgcagcata cgtaccggat cttcacggta gcgcgtttcc gggttaccaa
     1261 tcagacggat aacgccgtcc ttcagatcct tcatgccgcc aacgtaatca cggacggtaa
     1321 aatccgctac gctgtaatac aggctgttga tagtgaaatc gcggcgctgg gcgtcttctt
     1381 cgatggagcc gaaaatgttg tcgcgcagca acatgccgtt ttgcccgcgt tgggaggtcg
     1441 tgcggtcgct gacgttacct tcgtggtgtc cacggaaggt cgcaacttcg ataatctccg
     1501 ggccaaacat tacatgagcc agacggaaac ggcgacccac caggcggcag ttacggaaca
     1561 gtttgcgcac ctgctcaggc gtggcgttag tggttacgtc aaaatctttc ggctttttgc
     1621 caagtaacag gtcgcgcacg ccgccgccaa ccagccaggc ttcgtatccc gctttattga
     1681 gcctgtacat taccttcagg gcattttcac tgatatcttt gcgggaaata gcatgctgct
     1741 cacgcgggat caccgtcacc tgtggacggg cgactgcctg ttcagcctcg ctttcctcgc
     1801 ggcttagcac cttgcggcaa aaattagcga ctcgggtaaa aatagtacac ctcggtagtg
     1861 tcaaacatca ttcaggacaa aaaaatagcg gctaatcata gctcagcatg acgcatttga
     1921 gaatgttgaa tttacaattg ccgactcggg cacggcggta agccgccagt ttttgacggc
     1981 tgactgaagg atttgctcga cgctgaaatc ctgccagtgt gcttctgcct gctgccccag
     2041 aaattgaagt gccgcgatta gtaccgggcg tggatcgcct ttcggcaacg caggcgcatg
     2101 attctgcttg gaaagtttag cgccttgtgg attaagcgcc agcggcagat gaatgtaatc
     2161 tggcactttc cagccaaaaa gctggtacag cgagatttgc cttactgttg gttcaatcag
     2221 atcagcccca cgcactattt ctgtaacgcc ctggaaatga tcatcaacca caacagccag
     2281 gttgtaggcg aacaacccat cacggcgatg aatgataaaa tcttcccgtg ccagtttttc
     2341 gtcggcgtga ataatgccgc gcagctggtc agtaaattgc gtgaccggat gctgctggcg
     2401 gatacgcact gcggcgttgt ctggtccatg atgcaacacc cggcaatgac cgtcgtaaat
     2461 accgccaatg ctttgaatac gcgcacgcgt acaggtgcag taataactta gtccttgttc
     2521 atgtaaccag gcgagtgctt cacgataggc gtcgtgacgt tgcgattgcc agagaacatc
     2581 gccgtcccag tgcagaccgt aatgttccag ctggcgcagg atagtttctg cggcaccggg
     2641 aacttcacga ggcgggtcga tatcttctat gcgtaccagc cagcgacctt gccgggcgcg
     2701 agcctgcaaa tagctgccga gcgcggcgat cagagagcca aaatgaagct cgccggaagg
     2761 agagggggcg aagcggccaa tatactgtgt gtctgtcatc tctttgaaca aaaaataagg
     2821 cgggagcatt tcccgcctgt ggtaaacgtg atggaacggc tgtaattagc cagccatctg
     2881 tttttcgcga atttcagcca gcgttttgca gtcgatgcac agatcggctg tcgggcgcgc
     2941 ttccagacgg cgaataccaa tttcaacacc gcaggattcg cagtagccga aatcttcgtc
     3001 ttccactttt ttcagcgtct tctcgatctt tttgatcagc ttacgctcgc gatcgcggtt
     3061 acgcagttcg aggctgaact cttcttcctg ggctgcacgg tctaccgggt ccgggaagtt
     3121 ggctgcttca tcctgcatat gtgtaacggt gcgatcgact tcatccctga gttgattacg
     3181 ccatgcttcc agaatacgac ggaagtgcgc cagctgggct tcattcatat actcttcgcc
     3241 cggcttctcc tgatatggtt ccaccccagc gatggcgaga atactcaggg acgatgtttt
     3301 acggttttgc ccttcttgca tgttgcttct ccttaacacg cactatcgat ccccatgttc
     3361 gggggaaaaa tgaggccgct ataaatagca gatgcttttc cggatagcaa ttatctaaac
     3421 gtaacacttg acaactgtgt gaggaaaagc gtatttgcgc acgcgaccag aatgtaaatt
     3481 aaccagttac ttactttact acaatgtaac cggcagtgat tttttaagag ccatgccttc
     3541 agcagaaatt tccgctttgt aagccagaat ttctaccccc ctctgttgag cttctgacaa
     3601 tagttgcgcg tatttctcat cgatgtggcg cgcgggtgaa aaccgtgtaa tggctgaatg
     3661 cagcacggcg aaaaagataa ccgcacgctg gccttcagcc gctacgctca tcaactcccg
     3721 aaggtgtttc tgacctcgtt cagtgaccgc atcgggaaaa tatccctgtt cgttctccgc
     3781 taacgtaacc gatttcactt caatatagca gtctggacgc gaatccgcct gcaacataaa
     3841 gtcaatacgg ctgcgttctg cgccgtattt tacttcgctt ttcagcgagc tatagcctga
     3901 cagttctgaa attgattcat taaggatagc ctctttcgtc aacctgttag cccaaagcgt
     3961 gttgacgcaa ataaatgcgc cgctctggct ttgagttaat tcccaggtgt gtgggtattt
     4021 ccgtttggtg ttgtctgaag tcgaatacca gacggtatcg ccaggcgttg cacaaccggt
     4081 catcgcaccc gtattcgggc agtgtagcgt taattcgcga ccatcgggtg tgatcacatc
     4141 ggctaaaaaa cgtttgtaac gctgaattag cgtcgcgcgc tgtagagggg gagaaaattc
     4201 cattgcgaca atccttgtta ttgcgttagc gcccagcgtt ttagcggcgt gtagcgtgtg
     4261 cgtccacggg caaacgagga ggcgtaaagg gtgaactccg tcaccgcata cgaccagtta
     4321 aaacctggcg gcgggattgt caccgcctcg ctggcgtcgc gcaataaggt aatatgtgga
     4381 tgaaacggac gattgctttg aaaacaaccg ctgcgggcag cctgtgaacg gagcatattc
     4441 gccagctgga ttaagccgcg tggcggctga cgcatcccta accacaccac acgcgaacgc
     4501 agccattgtc cggcgtcatc aagcgtgagt gtgaaaccag gttgacgaat ccgtccggct
     4561 aaaagagaaa gcgccttctc tttctcggcg ctcacttcgc ctaaaaatgc cagagtcaga
     4621 tgcaaattat cggcggcgac cggacgtccc gcctcaggtg ggaagtgtgt ggcgcgccaa
     4681 tggataatct gttcgcggat ttctgcaggt aagtcgatag caaagaacag acgttgcggt
     4741 tcagacatgt gaggcactcg gttatgaatt accgcgatgc tacaatgtgg cgcgaagaat
     4801 gttaaccctc tggagcgttt tgtgtcgtcg ttgcccgttg ctgccgtctt acctgaatta
     4861 cttaccgctc tcgattgtgc gccgcaggta ttattaagtg cgccgaccgg ggccgggaaa
     4921 tcaacctggc tgccgctgca actgctggcg catcccggca ttaacgggaa aattatcctg
     4981 ctggagccgc gtcgtctggc ggcgcgtaac gtcgcgcaac ggctggcgga gctgcttaac
     5041 gaaaagccag gcgataccgt tggctaccgg atgcgtgcgc aaaactgcgt cgggccgaat
     5101 acccgcctgg aagtggttac cgaaggcgtg ctgacgcgca tgatccagcg tgacccggaa
     5161 ctgagcggtg ttggactggt gatccttgat gaatttcatg agcgcagctt gcaggcggat
     5221 ttggcgttgg cgctgttact cgatgtgcaa caaggtctgc gtgatgacct taaactgctg
     5281 attatgtcgg ctaccctgga caacgaccgc ttgcagcaaa tgctgccaga agcgcctgtc
     5341 gtcatctcag aagggcgctc gtttccggtt gaacgccgtt atttaccgct gcccgcgcat
     5401 cagcgttttg acgatgccgt tgcggtagcc accgctgaaa tgctgcgtca ggaaagcgga
     5461 tcattactgt tatttttacc tggcgtcgga gaaattcagc gtgtgcagga acaactggct
     5521 tcgcgcatcg gcagtgatgt attgctctgc ccgctgtatg gcgcgttgtc gctgaacgat
     5581 cagcgaaaag cgatcctccc ggcaccgcaa gggatgcgca aagtggtgct ggcgaccaat
     5641 attgctgaaa ccagtttaac cattgaaggt attcgtctgg tggtggattg tgcccaggag
     5701 cgtgtggcgc gttttgatcc gcgcacgggg cttacgcgac tgattactca acgcgttagc
     5761 caggcatcca tgacgcagcg tgccgggcgc gccgggcgtc tggagccggg tatcagcctg
     5821 catttaatcg ccaaagaaca agcagaacgc gccgcggcgc aaagtgaacc ggagatctta
     5881 caaagcgatc tttccggttt gctgatggaa ttactgcaat ggggatgcag cgatccggcg
     5941 cagatgagct ggctggatca accgccagta gtgaatctac tggccgcgaa acgtctgtta
     6001 caaatgctgg gggcactgga gggtgaacgg cttagtgcgc aagggcaaaa aatggcagcg
     6061 ctgggtaacg atccgcgttt agcggcaatg ctggttagcg cgaagaacga cgacgaagct
     6121 gctaccgcgg caaaaattgc cgccattctc gaagagccgc cacggatggg caatagtgac
     6181 ctgggcgtgg cgttttcgcg caatcaacca gcctggcagc aacgtagtca gcaactgtta
     6241 aaacgcttaa acgtacgtgg cggtgaggca gacagttcgc ttatcgcgcc gctacttgcc
     6301 ggggcgtttg ccgatcgcat tgctcgtcgc cgtgggcaag atggacgcta tcaactggca
     6361 aacggcatgg gagcgatgct cgatgccaac gacgcgctaa gccgccacga atggttgatc
     6421 gcaccgttat tattgcaggg cagcgcctcg ccggatgcgc ggattttact ggcgctgctg
     6481 gtcgatattg atgagttagt acaacgctgc ccgcagctgg tacagcagtc tgacactgtg
     6541 gagtgggatg acgcgcaagg tacgctgaaa gcctggcgtc ggctacaaat cggtcagttg
     6601 acggtgaaag tgcagccgct ggcgaaaccg tcagaagacg agttgcatca ggcgatgctt
     6661 aatggcatcc gtgataaagg tttaagcgtg ctcaactgga cggcggaagc ggaacagcta
     6721 cgcttgcgtt tgttatgcgc cgcaaagtgg ttgccggaat atgactggcc agcggttgat
     6781 gatgaaagtt tattggcagc gctggaaacg tggctgctgc cacatatgac tggcgtacat
     6841 tcactacgcg gcctgaaatc actcgacatt tatcaggcac tacgcggatt acttgattgg
     6901 ggaatgcagc aacgtctgga tagtgaattg cctgcgcatt acactgtgcc gacgggaagc
     6961 cggatcgcca ttcgttatca tgaagataac ccgcccgcgc tggcggtgag aatgcaagag
     7021 atgtttggcg aggccaccaa tccgacgatc gcccaggggc gcgtgccgct ggtgctggag
     7081 ttgctttcac ctgcccaaag gccattacaa atcacacgag atttgagcgc cttctggaaa
     7141 ggagcgtacc gtgaggtgca aaaagagatg aaagggcgtt atcccaaaca tgtctggccg
     7201 gacgacccgg caaatactgc accgacgcga cggacgaaaa agtattcgta aggttggttt
     7261 tctccctctc cctgtgggag agggccgggg tgagggcatc agcgcgcacg ttcaccctca
     7321 ccctaaccct ctccctcaag ggagagggga ccgatcgagc acaaattttg agagatatct
     7381 tcttctgtct tgtaacagaa gaacagaaaa tcgggctttt gcgcctgaat attgcggaga
     7441 aaaagcatgg ccgggaatga ccgcgagcca attggacgca aagggaaacc gacgcgtccg
     7501 gtcaaacaaa aggtaagccg tcgtcgttac gaagatgacg atgattacga cgattatgat
     7561 gactatgagg atgaagaacc gatgccgcgc aaaggtaagg gcaaaggcaa agggcgtaag
     7621 cctcgtggca aacgcggctg gctatggcta ctgctaaaac tggctatcgt ttttgccgtg
     7681 ctgatcgcca tttacggcgt ttatctcgat caaaaaattc gtagccgtat tgatggcaag
     7741 gtctggcaac tgcctgcggc agtttatggc cgaatggtca atcttgagcc agacatgacc
     7801 atcagcaaga acgagatggt gaagctgctg gaggcgaccc agtatcgtca ggtgtcgaaa
     7861 atgacccgtc ctggcgaatt taccgtgcag gccaacagca ttgagatgat tcgccgtccg
     7921 tttgatttcc cggacagtaa agaaggacag gtgcgcgcgc gtctgacctt tgatggcgat
     7981 catctggcga cgatcgtcaa tatggagaac aaccgtcagt tcggtttctt ccgtcttgat
     8041 ccgcgtctga tcaccatgat ctcttcgcca aacggtgagc agcgtctgtt tgtgccgcgc
     8101 agtggtttcc cggatttgct ggtggatact ttgctggcga cagaagaccg tcatttttac
     8161 gagcatgatg gaatcagtct ctactcaatc ggacgtgcgg tgctggcaaa cctgaccgcc
     8221 ggacgcacgg tacagggtgc gagtacgctg acgcaacagc tggtgaaaaa cctgttcctc
     8281 tccagcgagc gttcttactg gcgtaaagcg aacgaagctt acatggcgct gatcatggac
     8341 gcgcgttaca gcaaagaccg tattcttgag ctgtatatga acgaggtgta tctcggtcag
     8401 agcggcgaca acgaaatccg cggcttcccg ctggcaagct tgtattactt tggtcgcccg
     8461 gtagaagagc taagcctcga ccagcaggcg ctgttagtcg gtatggtgaa aggggcgtcc
     8521 atctacaacc cgtggcgtaa cccaaaactg gcgctggagc gacgtaatct ggtgctgcgt
     8581 ctgctgcaac agcaacagat tattgatcaa gaactctatg acatgttgag tgcccgtccg
     8641 ctgggggttc agccgcgcgg tggggtgatc tctcctcagc cagcctttat gcaactggtg
     8701 cgtcaggagc tgcaggcaaa actgggcgat aaggtaaaag atctctccgg cgtgaagatc
     8761 ttcactacct ttgactcggt ggcccaggac gcggcagaaa aagccgccgt ggaaggcatt
     8821 ccggcactga agaaacagcg taagttgagc gatcttgaaa ctgcgattgt ggtcgtcgac
     8881 cgctttagtg gtgaagttcg tgcgatggtc ggaggttctg agccgcagtt tgcgggctac
     8941 aaccgtgcga tgcaggcgcg tcgttcgatt ggttcccttg caaaaccagc gacttatctg
     9001 acggccttaa gccagccgaa aatctatcgt ctgaatacgt ggattgcgga tgcgccaatt
     9061 gcgctgcgtc agccgaatgg ccaggtctgg tcaccgcaga atgatgaccg tcgttatagc
     9121 gaaagcggca gagtgatgct ggtggatgcg ttgacccgtt cgatgaacgt gccgacggta
     9181 aatctgggga tggcgctggg gctgcctgcg gttacggaga cctggattaa actgggcgta
     9241 ccgaaagatc agttgcatcc ggttccggca atgctgctgg gggcgttgaa cttaacgcca
     9301 atcgaagtgg cgcaggcatt ccagaccatc gccagcggtg gtaaccgtgc accgctttct
     9361 gcgctgcgtt cggtaatcgc ggaagatggc aaagtgctgt atcagagctt cccgcaggcg
     9421 gaacgtgctg ttccggcgca ggcggcgtat ctgacactat ggaccatgca gcaggtggta
     9481 caacgcggta cgggtcgtca gcttggggcg aaatacccga acctgcatct ggcagggaaa
     9541 acagggacta ccaacaataa cgtagatacc tggtttgcgg gcattgacgg cagcacggtg
     9601 accatcacct gggtcggccg tgataacaac cagccgacca aactgtatgg tgccagcggg
     9661 gcaatgtcga tttatcagcg ttatctggct aaccagacgc caacgccgct gaatcttgtt
     9721 ccgccagaag atattgcaga tatgggcgtg gactacgacg gcaactttgt ttgcagcggt
     9781 ggcatgcgta tcttgccggt ctggaccagc gatccgcaat cgctgtgcca gcagagcgag
     9841 atgcagcagc agccgtcagg caatccgttt gatcagtctt ctcagccgca gcaacagccg
     9901 caacagcaac ctgctcagca agagcagaaa gacagcgacg gtgtagccgg ttggatcaag
     9961 gatatgtttg gtagtaatta acatctaagc gtgaaatacc ggatggcgag ttgccatccg
    10021 gtaaaataac atcccatcta agatattaac cctttctttt catctggttg tttattaacc
    10081 cttcaggaac gctcagattg cgtaccgctt gcgaacccgc cagcgtttcg aatattatct
    10141 tatctttata ataatcattc tcgtttacgt tatcattcac tttacatcag agatatacca
    10201 atggcgcgtt ccaaaactgc tcagccaaaa cactcactgc gtaaaatcgc agttgtagta
    10261 gccacagcgg ttagcggcat gtctgtttat gcacaggcag cggttgaacc gaaagaagac
    10321 actatcaccg ttaccgctgc acctgcgccg caagaaagcg catgggggcc tgctgcaact
    10381 attgcggcgc gacagtctgc taccggcact aaaaccgata cgccgattca aaaagtgcca
    10441 cagtctattt ctgttgtgac cgccgaagag atggcgctgc atcagccgaa gtcggtaaaa
    10501 gaagcgctta gctacacgcc gggtgtctct gttggtacgc gtggcgcatc caacacctat
    10561 gaccacctga tcattcgcgg ctttgcggca gaaggccaaa gccagaataa ctatctgaat
    10621 ggcctgaagt tgcagggcaa cttctataac gatgcggtca ttgacccgta tatgctggaa
    10681 cgcgctgaaa ttatgcgtgg cccggtttcc gtgctttacg gtaaaagcag tcctggcggc
    10741 ctgttgaata tggtcagcaa gcgtccgacc accgaaccgc tgaaagaagt tcagtttaaa
    10801 gccggtactg acagcctgtt ccagactggt tttgacttta gcgattcgtt ggatgatgac
    10861 ggtgtttact cttatcgcct gaccggtctt gcgcgttctg ccaatgccca gcagaaaggg
    10921 tcagaagagc agcgttatgc tattgcaccg gcgttcacct ggcgtccgga tgataaaacc
    10981 aattttacct tcctttctta cttccagaac gagccggaaa ccggttatta cggctggttg
    11041 ccgaaagagg gaaccgttga gccgctgccg aacggtaagc gtctgccgac agactttaat
    11101 gaaggggcga agaacaacac ctattctcgt aatgagaaga tggtcggcta cagcttcgat
    11161 cacgaattta acgacacctt tactgtgcgt cagaacctgc gctttgctga aaacaaaacc
    11221 tcgcaaaaca gcgtttatgg ttacggcgtc tgctccgatc cggcgaatgc ttacagcaaa
    11281 cagtgtgcgg cattagcgcc agcggataaa ggccattatc tggcacgtaa atacgtcgtt
    11341 gatgatgaga agctgcaaaa cttctccgtt gatacccagt tgcagagcaa gtttgccact
    11401 ggcgatatcg accacaccct gctgaccggt gtcgacttta tgcgtatgcg taatgacatc
    11461 aacgcctggt ttggttacga cgactctgtg ccactgctca atctgtacaa tccggtgaat
    11521 accgatttcg acttcaatgc caaagatccg gcaaactccg gcccttaccg cattctgaat
    11581 aaacagaaac aaacgggcgt ttatgttcag gatcaggcgc agtgggataa agtgctggtc
    11641 accctaggcg gtcgttatga ctgggcagat caagaatctc ttaaccgcgt tgccgggacg
    11701 accgataaac gtgatgacaa acagtttacc tggcgtggtg gtgttaacta cctgtttgat
    11761 aatggtgtaa caccttactt cagctatagc gaatcgtttg aaccttcttc gcaagttggg
    11821 aaggatggta atattttcgc accgtctaaa ggtaagcagt atgaagtcgg cgtgaaatat
    11881 gtaccggaag atcgtccgat tgtagttact ggtgccgtgt ataatctcac taaaaccaac
    11941 aacctgatgg cggaccctga gggttccttc ttctcggttg aaggtggcga gatccgcgca
    12001 cgtggcgtag aaatcgaagc gaaagcggcg ctgtcggcga gtgttaacgt agtcggttct
    12061 tatacttaca ccgatgcgga atacaccacc gatactacct ataaaggcaa tacgcctgca
    12121 caggtgccaa aacacatggc ttcgttgtgg gctgactaca ccttctttga cggtccgctt
    12181 tcaggtctga cgctgggcac cggtggtcgt tatactggct ccagttatgg tgatccggct
    12241 aactccttta aagtgggaag ttatacggtc gtggatgcgt tagtacgtta tgatctggcg
    12301 cgagtcggca tggctggctc caacgtggcg ctgcatgtta acaacctgtt cgatcgtgaa
    12361 tacgtcgcca gctgctttaa cacttatggc tgcttctggg gcgcagaacg tcaggtcgtt
    12421 gcaaccgcaa ccttccgttt ctaatttctc ttttggggca cggatttccg tgcccatttc
    12481 acaagttggc tgttatgcag gaatacacga atcattccga taccactttt gcactgcgta
    12541 atatctcctt tcgtgtgccc gggcgcacgc ttttgcatcc gctgtcgtta acctttcctg
    12601 ccgggaaagt gaccggtctg attggtcaca acggttctgg taaatccact ctgctcaaaa
    12661 tgcttggccg tcatcagccg ccgtcggaag gggagattct tcttgatgcc caaccgctgg
    12721 aaagctggag cagcaaagcg tttgcccgca aagtggctta tttgccgcag cagcttcctc
    12781 cggcagaagg gatgaccgtg cgtgaactgg tggcgattgg tcgttacccg tggcatggcg
    12841 cgctggggcg ctttggggcg gcagatcgcg aaaaagtcga ggaagctatc tcgctggttg
    12901 gcttaaaacc gctggcgcat cggctggtcg atagtctctc tggcggcgaa cgtcagcggg
    12961 cgtggatcgc catgctggtg gcgcaggata gccgttgtct gttgctcgac gaaccgacct
    13021 cggcgctgga tatcgcccac caggttgatg tgctgtcgct ggtgcaccgt ttaagtcagg
    13081 agcgtggcct gacggtcatt gccgtgttgc acgatatcaa tatggcggca cgctactgtg
    13141 attatctggt cgccctgcgc ggcggtgaaa tgattgctca gggaacgcct gcggaaatta
    13201 tgcgcggcga aaccctcgaa atgatttatg gcatcccgat gggtattttg ccgcatccgg
    13261 cgggtgctgc acctgtgagt tttgtttatt gatgagcggc ttacctctta tttcgcgccg
    13321 tcgactgtta acggcgatgg cgctttctcc gttgttatgg cagatgaata ccgcccacgc
    13381 ggcggctatt gatcccaatc gtattgtggc gctggagtgg ttgccggtgg aattactgct
    13441 ggcgctcggc atcgtgcctt acggcgtggc ggataccatc aactatcgcc tgtgggtcag
    13501 cgaaccacca ttgccggact cagtgatcga cgtcggtttg cgcacagaac ctaaccttga
    13561 actgctgacc gaaatgaaac catcgtttat ggtctggtcg gcaggatatg gcccttcacc
    13621 agaaatgctg gctcgtattg cgccgggtcg cggatttaac ttcagtgacg gcaaacagcc
    13681 gttggcgatg gcgcgtaaat cgctgacgga aatggcagat ttacttaacc tgcaaagcgc
    13741 agcggaaacg catttagcgc aatatgaaga ctttatccgc agcatgaaac cccgctttgt
    13801 gaagcgtggt gcgcgtccgt tattgctgac gacgcttatc gatccgcgcc atatgctggt
    13861 cttcggtcca aacagcttgt tccaggaaat tcttgatgag tacggcatcc caaatgcctg
    13921 gcaaggggaa accaacttct ggggcagtac cgccgtcagt atcgatcgtc tggcggcgta
    13981 taaagacgtt gatgtgctct gttttgatca cgacaacagc aaagacatgg atgcgctaat
    14041 ggcaacgccg ctgtggcagg ccatgccgtt tgtccgcgcc ggacgctttc agcgcgtacc
    14101 tgcagtctgg ttttatggtg cgacgctctc ggcaatgcac tttgtgcgcg ttctggataa
    14161 cgccatcgga ggtaaagcgt gagtaaacga attgcgcttt tcccggcgtt attgctggcg
    14221 ctgttagtga ttgtcgctac ggcgctcacc tggatgaact tctcgcaggc gctgccgcgt
    14281 agccagtggg cgcaggctgc ctggtcgccg gatattgacg tcatcgagca gatgattttt
    14341 cactacagct tgttgccgcg tctggtgatt tcgctgctgg tgggcgcggg tctggggctg
    14401 gtgggcgtgc tgtttcagca agtgctgcgt aacccgctgg cggagccgac gacgcttggc
    14461 gttgctacag gcgcgcaact ggggattacc gtcactacgc tctgggcgat ccctggtgcg
    14521 atggcgagcc agtttgctgc gctggcaggg gcttgtgttg ttggcttaat tgtctttggc
    14581 gtcgcgtggg ggaaacggct gtcgccggta acgctgattc tcgcggggtt ggtagtgagc
    14641 ctttattgcg gcgcaatcaa tcagttactg gttatcttcc atcatgacca actgcaaagc
    14701 atgtttctgt ggagcactgg aacgctgacg caaaccgact ggggcggcgt tgagcgttta
    14761 tggccgcagc tgctgggcgg tgtgatgctg acgttgctgc tacttcgtcc gttaaccctg
    14821 atggggcttg atgatggcgt ggcgcgcaat ctcgggctgg ccttgtcgct tgcgcgtctg
    14881 gcggcgctgt cgctggcgat tgtcatcagt gcgctgctgg tgaacgctgt ggggattatc
    14941 ggctttatcg ggttgttcgc gccgctgctg gcaaaaatgc tgggggcgcg gcgtctgctg
    15001 ccacgactga tgctggcgtc gttgattggt gcgctgatcc tctggctttc cgatcaaatc
    15061 atcctctggc tgactcgcgt gtggatggaa gtgtccaccg gttcggtcac tgcgttgatc
    15121 ggtgcgccgc tgctactgtg gctgttgccg cgtttacgca gcattagcgc gccggatatg
    15181 aaggtcaacg atcgtgtcgc ggctgaacgc caacatgtgc tggcgtttgc cctcgcgggc
    15241 ggcgtgctgc tgttgatggc tgtggtggtg gcgctgtcgt ttggtcgtga tgcgcacggc
    15301 tggacgtggg cgagcggggc gttgctcgag gatttaatgc cctggcgctg gccgcgaatt
    15361 atggcggcgc tgtttgcggg cgtcatgctg gcggtggcgg gctgtattat tcagcgactg
    15421 accggaaacc cgatggcaag cccggaagtg ctggggatta gctccggcgc ggcgtttggc
    15481 gtggtgttga tgctgtttct ggtgccgggt aatgcctttg gctggctgtt acctgcaggc
    15541 agtctcggcg cggcggtgac gctgttgatc attatgatcg ccgccggccg cagtggattt
    15601 tccccacacc gtatgttact ggcggggatg gcgttaagca ccgcgttcac catgcttttg
    15661 atgatgttgc aggcaagtgg tgacccgcga atggcgcaag tgctgacctg gatttccggt
    15721 tcgacctaca acgcgaccga tgcgcaggtc tggcgcaccg gaattgtgat ggtgattttg
    15781 ctggcgatta ccccgctgtg ccgccgctgg ctgaccattt taccgctggg tggtgatacc
    15841 gcccgagccg taggaatggc gctgacgccg acgcgaattg cgctgctgct gttagcggct
    15901 tgcctgacgg cgaccgcgac gatgactatt ggaccgttga gttttgttgg tttaatggca
    15961 ccgcatattg cgcggatgat gggctttcga cggacgatgc cacacatcgt aatttcggcg
    16021 ctggtgggtg gtttactgct ggtgttcgct gactggtgtg ggcggatggt gctgtttcca
    16081 ttccagatcc cggcggggct gctgtcaacc tttatcggcg cgccatattt tatctatttg
    16141 ttgagaaagc agagccgtta atttttccat ataacggccc tgtacgcctg gacggataaa
    16201 gcgtttacgc gacaacggat gcccgatgcg acgctggcgc gtcttatcgg gcctacaaac
    16261 ggccccgaat cgtaggtcgg ataaggcgtt cacgccgcat ccgacaaacc atgctggatc
    16321 acaacttcgc aaacacccga cgtgcagcat cgatggtgtt attgatatct tccatgctgt
    16381 gcgccacgga cataaagccc gcttcaaacg ctgacggtgc caggtaaaca ccttcgtcca
    16441 gcatcatatg gaagaaacgc ttaaagcgtt ccacgtcaca ggccatcaca tcctgatagc
    16501 acgtcacgga ctcggcgtcg gtaaagaaaa taccgaacat gccgccaacg tggttaacga
    16561 ccagcggaat tccggcttct tctgccgctt ccagcagacc ttctgccaga cgtgttgtca
    16621 gctcatccag cgtttcgtga acgcccggct gcgcgacttc attcagacag gcgaaacccg
    16681 ctgccatcgc aatcgggtta ccggaaagcg tacccgcctg atagaccgga cccgtcgggg
    16741 ccagcgcatc cattacatca cgacgaccac cgaatgcgcc taccggcatt ccaccgccga
    16801 tgattttgcc gaggcaggtt aaatctggca ctacgccgta ataatcctgt gcgccagcta
    16861 gcgctacgcg gaaaccggtc atcacttcat cgatgatcag caacgcgcca aattcgtcgc
    16921 acagcgcgcg cagacctggc aggaactctg gcagcggcgg aacacagttc atattgcctg
    16981 ccaccggctc gacgataata caggcaatct cttgcgggta ttgctcaaat gcggcgcgta
    17041 cagaagccag atcattataa gtacaggtta aggtatgttt ggcgaaatct gccggaacgc
    17101 ccggcgagtt tggctggcct aacgtgagtg cgccagaacc ggctttcacc agcaggcagt
    17161 cagcgtgacc atggtaacac ccttcaaatt taataatttt gtcgcgaccg gtaaaaccac
    17221 gggccaggcg gatggcgctc atggtcgctt cagtgccgga gttcaccatg cgcaccatat
    17281 ccatggtcgg gaccagttcg gtcaccagtt gcgccatttt cacttccatt tcggttggtg
    17341 caccaaagct taaaccacgc tcggcggctt caatcacggc attgcggatt gccggatggt
    17401 tatggcccag caccatcggc ccccaggaac cgacataatc gatataggct ttgccatcaa
    17461 catcgtacag ataagcgccg tccgcttttt cgataaacag tggagtgccg cccacgccag
    17521 taaaggcgcg aacaggggag ttcacaccgc cagggatcag ctcgcgcgct gcgctgtaaa
    17581 gattttcaga cttactcatg gagggttcct gattcgtaga aaaagtgaat ggctgctatt
    17641 ctatgttatt cataacaagt taaatactcg tcaaacatca ggctgcttgt actggtgcaa
    17701 tcctgatttc ttagagtata aaagttttgt gcatttgaaa cattacgctt tgcaaaggat
    17761 tttcatggaa cgtgcgagta aaatgccgtc atcttatttg tatgaccaat aagtgatcat
    17821 tggatgaaaa ctgatactcc ctctttagaa acaccgcagg ccgcgcgcct gcgacgcaga
    17881 caactgattc gccaacttct tgagcgcgat aaaaccccgt tagccatttt gtttatggcg
    17941 gcagtcgtcg gcacgcttgt tgggctggca gcggttgctt ttgacaaagg tgtcgcctgg
    18001 ttgcagaacc aacgtatggg ggcgctggta catactgctg ataattattc gcttctgtta
    18061 accgtcgctt ttctctgttc ggcggtgctg gcgatgtttg gctacttttt ggtgcgcaaa
    18121 tacgcgccgg aagcaggtgg ttcggggatc ccggaaattg aaggggcgct ggaagatcaa
    18181 cgtcccgttc gctggtggcg tgtattgccg gtgaagttct ttggcgggct ggggacactc
    18241 ggcggaggca tggtgttggg gcgcgaaggg ccaaccgtgc agatcggcgg taacattggc
    18301 cgtatggtgc ttgatatttt ccgcctgaaa ggtgacgaag ctcgccatac gctgctggca
    18361 accggtgctg ctgcggggct ggctgcggcc tttaacgcgc cgctggcggg tattttgttt
    18421 attatcgaag agatgcgtcc gcagtttcgc tatacgttaa tttcgattaa agcggtattt
    18481 attggtgtca ttatgtcgac cattatgtac cggattttta atcatgaagt tgcgttgatt
    18541 gacgtcggta aactttctga tgcgccgctt aatacgctgt ggctttatct gatcctcggt
    18601 attatttttg gcattttcgg ccctattttt aataaatggg tgctggggat gcaggatttg
    18661 ctgcaccgtg tgcacggcgg caatattacc aaatgggtgc taatgggcgg tgcgattggc
    18721 ggtctgtgtg gattgctggg gtttgtggca ccagcaacgt cgggcggcgg ttttaacctg
    18781 attcctatcg ctaccgcggg gaatttcagc atgggaatgc tggtgtttat cttcgtcgcg
    18841 cgggtcatta ccaccttact ctgcttctct tccggcgcgc cgggcggtat ttttgccccg
    18901 atgctggcgc tgggtactgt gctgggaacc gctttcggaa tggttgccgt tgagctgttt
    18961 ccgcaatatc accttgaggc ggggacgttt gctattgccg gaatgggggc attactggcg
    19021 gcatctattc gcgcgccgtt aacggggatc attctggttc tggagatgac cgataactac
    19081 cagctcattt tgccaatgat tattaccggt cttggcgcaa cactattagc gcaatttacc
    19141 ggcgggaaac cgctatactc ggcgattctt gcgcgcacgc tggcaaaaca ggaagctgag
    19201 caactggcgc gaagcaaggc cgcatcagcc agcgagaata cttgaacgaa ataccagggt
    19261 attagataat ggcgattatt attgggttag aatttgccca attgccgatg tcgtttggag
    19321 caaaatatga gtgatgacgt agcactgccg ctggagttta ccgacgcagc agccaacaaa
    19381 gttaaaagcc tgatcgctga cgaagataac ccgaatctga aattacgcgt gtatatcacc
    19441 ggtggcggtt gcagcggctt ccagtatggt ttcacctttg atgatcaggt gaacgaaggc
    19501 gatatgacca tcgaaaaaca gggcgttggc ctggtggttg atccgatgag cctgcaatat
    19561 ctggtcggcg gttccgttga ttataccgaa ggtctggaag gttctcgttt catcgtgacc
    19621 aacccgaacg cgaaaagcac ctgcggttgc ggttcttcct ttagtatcta atctgttgtt
    19681 catgtgccgg ataaactatc cggcacatct tctctcttca acgcccattc tcatccagcg
    19741 caaacgtcgg tagcttaaga tgccaacgaa tagccgccag ccgaatcaat agcgtcacga
    19801 ccatgcccat catactggct gtttccagtg gtacggaaaa tgtgtaataa gccgtagcgt
    19861 ggacaatacc gccgataata caggcagttg cgtagatttc tgtacgtaaa atcatgggga
    19921 tttcgcgggc cagaacatca cgaatgatcc cgccgccaac gccagtaatg acgcccatac
    19981 aaaccgcgat taacggaccg gcttccgcat taaaggcttt attcacgcca atgccgacaa
    20041 acaccgccag accaacggcg tccagcaccg gcaacatcca ttttggtaag cgtcttggct
    20101 ggcgcaccag cacgatggtc agcatgctgg tgaccattgc aacgaccaga tcggtgggat
    20161 ctttcaccca aaataccggg ccgtgatcca gcgccatgtc gcgaattgtc ccgccgccta
    20221 ctgcggttac cacgcccagt accagaacac caaaagggtc catacgcaat tttccggcta
    20281 acaaaacgcc ggagatggca aataccgctg tgccgactat atccagccaa tagacgagca
    20341 ttgttcaatc cccactgagc acctgaaaag gtcaggcgct aatctacctg tgaaagcgca
    20401 ttacagagct gttgtgcagc gaggataata cgtgggcttg cacgttcaaa ccagtcactc
    20461 gtgagaggaa taacgggaat tttgagctgt tcaccccagt attgtttgat tttaggaatt
    20521 tggtccggtc cgcctgtaat gacaatcgcc tgtggcgagc gtgctaacac ctgttcgcgg
    20581 ctaacttgcg gccagggaac ccggctgtct ttaaagatgt tttctccgcc acaaacttcg
    20641 agtacctggt tctgaatcga ctcttttcca ctggtaaatg gcggattaat gccgaattgc
    20701 agaaaaacac gttttttagg tttatcagca tattgcgctt tcaattgcgc gtactgatcc
    20761 agcagggatt gcgcggcttg ttcggccttg tctggttgcg gactccaggg ggccagttga
    20821 cgtaacgcat tggcaatttg ttcaatgctt gtcgcatcga cccacatcac ttttattccc
    20881 agcgaagcca gctggtcaac ctgccgctcg gcattacctc cacgccaggc aatcaccaga
    20941 tcgggtttca gcgcgacaat gcgttccaga ttcatcccct gccaggtgga aacctgctca
    21001 atcttttgcg cttgtggagg atagtcggaa tagctgctga ccccaaccgg cgtgatcccg
    21061 gcggcaaagg caagttcagt gttggcggga gaaagcgtga tgacgcgcgg cgcggcgttg
    21121 agccacagtg gcgcaagaaa agacagggcg accagcgccc tgaacagtga cttagccatg
    21181 tgcaagtttc tgcaccagtg actcaaccat caggctggac tgtttagcgg caacagccag
    21241 gaactcatcg aagctaagat gagactgttg atcggccacg tcggagatgg cgcgtacgac
    21301 aacaaacggg acgttgaaat tgtggcagac atgggcgatt gccgtcgctt ccatctctac
    21361 agcaatggcc tgtgggaagt tgtggcggat tttcgccaga ccaacagaac cgttgatgaa
    21421 agcgtcgccg ctaacaatca ggccacgtac agcgttaaga ttcagttcgg caatgcaggc
    21481 ctcagcggca gcgatcagtt tatcgtcagc tttaaagcct gccggacagc ctggtaactg
    21541 accgtattca taaccaaatg ccgtgacatc cgcgtcgtga taacgtgctt cgtccgagac
    21601 aacgatatcg cccactttca acgttggtgc caggccaccg gcagaaccgg tgttaataat
    21661 cacatctggc ttgcagtgtt ccaacagcaa agtggcaccc agcgccgcag cgactttacc
    21721 gatgcccgat ttcagaagcg caacctcggt tccattcagt tggccggtat agatttcgca
    21781 accgccgaga ctgatagttt gacggttttc gattttgtca cgcagcagcg taacttcttc
    21841 ttccattgca ccaatgatgc cgattttcat agatttactc gcgataagcc cgatttgaag
    21901 gcatagttta ccatgcgctt acggggaagc gtatttctca cgcgggagag gacatggcac
    21961 agattgattt ccgaaaaaaa ataaactggc atcgtcgtta ccgttcaccg cagggcgtta
    22021 aaaccgaaca tgagatcctg cggatcttcg agagcgatcg cgggcgtatc atcaactctc
    22081 cggcaattcg tcgtctgcaa caaaagaccc aggtttttcc actggagcgc aatgccgccg
    22141 tgcgcacgcg tcttacccac tcgatggaag tccagcaggt ggggcgctac atcgccaaag
    22201 aaattttaag ccgtctgaaa gagcttaaat tactggaagc atacggcctg gatgaactga
    22261 ccggtccctt tgaaagcatt gttgagatgt catgcctgat gcacgatatc ggcaatccgc
    22321 cgtttggtca ttttggcgaa gcggcgataa atgactggtt tcgccaacgt ttgcacccgg
    22381 aagatgccga aagccagcct ctgactgacg atcgctgcag cgtggcggca ctacgtttac
    22441 gggacgggga agaaccgctt aacgagctgc ggcgcaagat tcgtcaggac ttatgtcatt
    22501 ttgaggggaa tgcacaaggc attcgcctgg tgcatacatt gatgcggatg aatctcacct
    22561 gggcacaggt tggcggtatt ttaaaatata cccgtccggc gtggtggcgt ggcgaaacgc
    22621 ctgagacaca tcactattta atgaaaaagc cgggttatta tctttctgaa gaagcctata
    22681 ttgcccggtt gcgtaaagaa cttaatttgg cgctttacag tcgttttcca ttaacgtgga
    22741 ttatggaagc tgccgacgac atctcctatt gtgtggcaga ccttgaagat gcggtagaga
    22801 aaagaatatt taccgttgag cagctttatc atcatttgca cgaagcgtgg ggccagcatg
    22861 agaaaggttc gctcttttcg ctggtggttg aaaatgcctg ggaaaaatca cgctcaaata
    22921 gtttaagccg cagtacggaa gatcagtttt ttatgtattt acgggtaaac accctaaata
    22981 aactggtacc ctacgcggca caacgattta ttgataatct gcctgcgatt ttcgccggaa
    23041 cgtttaatca tgcattattg gaagatgcca gcgaatgcag cgatcttctt aagctatata
    23101 aaaatgtcgc tgtaaaacat gtgtttagcc atccagatgt cgagcagctt gaattgcagg
    23161 gctatcgggt cattagcgga ttattagaga tttatcgtcc tttattaagc ctgtcgttat
    23221 cagactttac tgaactggta gaaaaagaac gggtgaaacg tttccctatt gaatcgcgct
    23281 tattccacaa actctcgacg cgccatcggc tggcctatgt cgaggctgtc agtaaattac
    23341 cgtcagattc tcctgagttt ccgctatggg aatattatta ccgttgccgc ctgctgcagg
    23401 attatatcag cggtatgacc gacctctatg cgtgggatga ataccgacgt ctgatggccg
    23461 tagaacaata accaggcttt tgtaaagacg aacaataaat ttttaccttt tgcagaaact
    23521 ttagttcgga acttcaggct ataaaacgaa tctgaagaac acagcaattt tgcgttatct
    23581 gttaatcgag actgaaatac atgaaaaaaa ccacattagc actgagtgca ctggctctga
    23641 gtttaggttt ggcgttatct ccgctctctg caacggcggc tgagacttct tcagcaacga
    23701 cagcccagca gatgccaagc cttgcaccga tgctcgaaaa ggtgatgcct tcagtggtca
    23761 gcattaacgt agaaggtagc acaaccgtta atacgccgcg tatgccgcgt aatttccagc
    23821 agttcttcgg tgatgattct ccgttctgcc aggaaggttc tccgttccag agctctccgt
    23881 tctgccaggg tggccagggc ggtaatggtg gcggccagca acagaaattc atggcgctgg
    23941 gttccggcgt catcattgat gccgataaag gctatgtcgt caccaacaac cacgttgttg
    24001 ataacgcgac ggtcattaaa gttcaactga gcgatggccg taagttcgac gcgaagatgg
    24061 ttggcaaaga tccgcgctct gatatcgcgc tgatccaaat ccagaacccg aaaaacctga
    24121 ccgcaattaa gatggcggat tctgatgcac tgcgcgtggg tgattacacc gtagcgattg
    24181 gtaacccgtt tggtctgggc gagacggtaa cttccgggat tgtctctgcg ctggggcgta
    24241 gcggcctgaa tgccgaaaac tacgaaaact tcatccagac cgatgcagcg atcaaccgtg
    24301 gtaactccgg tggtgcgctg gttaacctga acggcgaact gatcggtatc aacaccgcga
    24361 tcctcgcacc ggacggcggc aacatcggta tcggttttgc tatcccgagt aacatggtga
    24421 aaaacctgac ctcgcagatg gtggaatacg gccaggtgaa acgcggtgag ctgggtatta
    24481 tggggactga gctgaactcc gaactggcga aagcgatgaa agttgacgcc cagcgcggtg
    24541 ctttcgtaag ccaggttctg cctaattcct ccgctgcaaa agcgggcatt aaagcgggtg
    24601 atgtgatcac ctcactgaac ggtaagccga tcagcagctt tgccgcactg cgtgctcagg
    24661 tgggtactat gccggtaggc agcaaactga ccctgggctt actgcgcgac ggtaagcagg
    24721 ttaacgtgaa cctggaactg cagcagagca gccagaatca ggttgattcc agctccatct
    24781 tcaacggcat tgaaggcgct gagatgagca acaaaggcaa agatcagggc gtggtagtga
    24841 acaacgtgaa aacgggcact ccggctgcgc agatcggcct gaagaaaggt gatgtgatta
    24901 ttggcgcgaa ccagcaggca gtgaaaaaca tcgctgaact gcgtaaagtt ctcgacagca
    24961 aaccgtctgt gctggcactc aacattcagc gcggcgacag caccatctac ctgttaatgc
    25021 agtaatctcc ctcaacccct tcctgaaaac gggaaggggt tctccttaca atctgtgaac
    25081 ttcaccacaa ctccatacat cttcatcatc ctttaggcat ttgcacaatg ccgtacgtta
    25141 cgtacttcct tatgctaagc cgtgcataac ggaggactta tggctggctg gcatcttgat
    25201 accaaaatgg cgcaggatat cgtggcacgt accatgcgca tcatcgatac caatatcaac
    25261 gtaatggatg cccgtgggcg aattatcggc agcggcgatc gtgagcgtat tggtgaattg
    25321 cacgaaggtg cattgctggt actttcacag ggacgagtcg tcgatatcga tgacgcggta
    25381 gcacgtcatc tgcacggtgt gcggcagggg attaatctac cgttacggct ggaaggtgaa
    25441 attgtcggcg taattggcct gacaggtgaa ccagagaatc tgcgtaaata tggcgaactg
    25501 gtctgcatga cggctgaaat gatgctggaa cagtcgcggt tgatgcactt gttggcgcag
    25561 gatagccgtt tgcgggaaga actggtgatg aacctgattc aggcagagga gaatactccc
    25621 gcacttactg aatgggcgca acggctgggg atcgatctca atcaaccgcg agtggtggct
    25681 attgttgagg tcgacagcgg tcagcttggc gtggacagcg caatggcgga gttacaacaa
    25741 ctgcaaaacg cgctgactac gcccgagcgt aataatctgg tggcgattgt ctcgctaacc
    25801 gaaatggtgg tgttgaaacc ggcgttgaac tcttttgggc gctgggatgc agaagatcat
    25861 cgtaagcgag ttgaacaact gattacccgc atgaaagagt acggccagct gcgttttcgc
    25921 gtttcactgg gcaactattt taccggtcct ggcagtattg cccgatccta tcgtacggcg
    25981 aaaacgacga tggtggtggg taaacagcgg atgccagaaa gtcgctgcta tttttatcag
    26041 gatctgatgt tacctgtgtt actcgacagt ttgcgtggcg actggcaggc caacgaactg
    26101 gcgcgaccgc tggcgcggct gaaaacgatg gacaataacg gcttgctgcg acgaacgctg
    26161 gcggcgtggt ttcgccacaa tgtgcaaccg ctggcaacgt caaaggcgtt gtttattcat
    26221 cgtaataccc tggagtatcg gcttaatcgt atatcggaac tgaccgggct tgatttgggc
    26281 aattttgatg acaggttgct gctgtatgtg gcgttacaac tggatgaaga gcggtaggtt
    26341 atgcgttaag gttgaggcgg cgctggctca ttcccctcag cccgaagggt agaggggaat
    26401 gcccgaatta accgtcagtt cgggattatt tacgcgttag tttttccaga tcggcttcaa
    26461 tctcgctgat cttattggtt acgactgact ccaggtgacg taagtcgtcg aggatcttac
    26521 gcttaagatc aacttcgctg cggtcacgct ggcagatttg atcaagctca tcaatgatat
    26581 accgtagatt cgggctgatt tcctggactt ctttataacc ctgacccaca ccatcagcga
    26641 cgaccgtttt acgctgacgc ggatatttaa acttaacgct cttggcgaaa aactcgcctt
    26701 tgtctttctg gaaatagatt ttcagaatat cgttgttggc ttcctgccgg aggctgtaac
    26761 gatcaatttc ttcaggattg gtaataccca gacttttcag attgtcgtac atagcgttac
    26821 ctcaaaatga gtcagtaaat tgtgcttatt ttagcatttg gcctggcccg cccggctcga
    26881 ctgtgatcgc agaaagcctt tttcttccag acttctatca tggcgtaaaa atcaaaaaat
    26941 tacctgcttt attctggtga taaaattcac gatctacacc agttccagca tcgttacttc
    27001 cgggcggcag ttcagacgca aaccatacaa actgcccacg ccacgggttg tgtagatgtg
    27061 tctttcgcca aaggcattta atccggcgac gtaacgttta tcttcgacag gggcaaaagg
    27121 ttcaccaacc aacggtacgc gcagttgccc gccgtgagta tggccgcaca gcatcagatc
    27181 ccagggttca tcacgcatga cttctttgct gtcgggatta tgcgccagca ccagtcttgg
    27241 cagattggct tcgctggcgg gaggcggttt gcattgtccg gcccataagt caccagtgcc
    27301 taccagttcg aattgcctgt tcggcgtggc gatcaccgta gcctggttaa acaacaccgt
    27361 gatgcccgct gatttcaacg tctcgccaat taagtgattt ttttctgtac caacagggcg
    27421 atcgtggttg ccgaagcagg caaacgtcgg cgcacattcg gcaagggggg agagtacgtc
    27481 actaaacgcc gaaaaattca gcgacatatc aaataatacg taatcgccgc ccagtaatat
    27541 caaatcgggc ttttgttcta tgccaagagc aatcgcgtca gaaatcaggc ttaaaggaac
    27601 aaaacgagag taatggagat cggccagaaa aagaattttg aatggtgctg cgttgtcttt
    27661 aaaaaaggcg aggcggtgac ggattaattc aaaccagcct ggctcacagt aatgcatata
    27721 accgaaacct gagctcgtgg ctatcgtcgc ggcagtagcc tgcaaaaatc ggcggcgtga
    27781 aatcatcgct catccctgca aaaaaatcgg gcagcgtcgt gctgcccgtg tgcatacttt
    27841 tagtcgatgg tacgcagcag ttcgttaatg ccgactttgc cgcgagtttt cgcgtcaact
    27901 ttcttaacga taaccgcaca gtagaggctg tatttgccat cttttgacgg cagattacct
    27961 gaaacaacca cagaccccgc cggaacgcga ccgtagtgga tttcgccggt ttcacggtcg
    28021 taaatacggg tgctctgacc aatgtatacg cccatggaaa tgacggaacc ttcttcgaca
    28081 atcacccctt caaccacttc agagcgcgcg ccgatgaagc aattatcttc aatgatggtt
    28141 gggttagcct gcagcggttc cagcacgccg ccgatgccca cgccaccgga aaggtggacg
    28201 tttttaccaa tctgcgcaca agaaccgacg gtcgcccagg tatcaaccat ggtgccttca
    28261 tcaacatatg cgccgatgtt gacgtaagac ggcatcagca cggtgttacg ggcaataaac
    28321 gcaccctgac gtaccgccgc tggtggcaca acgcggaagc cttctttctg gaaacgtgct
    28381 tcgtcgtagt cggcgaattt catcggcact ttgtcgaagt agcggctttc tgccccttcg
    28441 atcacctgat tatcattaat acggaaagag agcagcaccg cttttttcaa ccactgatgc
    28501 gtcacccact gaccgtcaat tttttccgct acacgcagtg cgccggaatc cagcagggcg
    28561 atcacctgat ttaccgcttc gcgggtaacg gtgtctgcat tggctggcgt gatctcggca
    28621 cggcgttcaa aagcggtttc aataatgttc tgtaactgct gcattgttaa actcttttca
    28681 tatcagtaaa cacatcaccc tttatcgttt ggattgaggg cctctgtcaa ccgctgatgc
    28741 acttcctgct gcaactcgtt attaagcgca cgccggtcag cggtggcaat tatgaataaa
    28801 tcttctactc gctcgccaat ggttgtaatt cgggcaccat gaagcgaaat tcccagatcg
    28861 gcaaaaattt tcccgactcg cgccagcagt ccaggttggt cgagggcgat cagttcgagg
    28921 aacgatttgc ggtcggtatg ggtcggcaaa aacgttactt cggtttcaac agtaaaatgg
    28981 cgtaatttgg caggttggcg acggggctgc ggtggctgcc agctactttg cgtcagtact
    29041 tgctccagac caaaccgaat aacctcatga cgatctgcgg acagcgggtt gccatcgggt
    29101 tccagcacga taaaggtatc catcgccata ccgtcgcgag tggtgaaaat ttgtgcgtcg
    29161 tgaacactta aattgcggcg gtctaattcg gcacagacgg cggcaaacag ataagggcgg
    29221 tccgggctcc agataaaaat ctcggtgcct ccacgcgtag cctgcgggct aagcaatacc
    29281 agcggtttgc ttaaatcatg ctgtaataaa tggcgggcat gccaggccag ttgatttggg
    29341 ctatggcgga caaaatagtt agcacgacag cgtgaccaaa tttggtgcag cgcctcttcg
    29401 tcgatgttat ccatgcgcag tagtgccagt gcctggagtt ggtgatggcg aacccgttcg
    29461 cgcatatccg gcgtgttttg cattccgcgt cgtagctgct tttcggtggc aaagtagagc
    29521 tcacgcaaca gactttgctt ccagctattc cacagcgttt cgttggtggc gcaaatgtca
    29581 gccacagtca ggcataccag atagcgcaga cgattttccg tttgcacttc ttcggcaaac
    29641 tgcttgatga cttccgggtc ctgaatatcg cggcgttggg cggtcaccga catcaacagg
    29701 tgctggcgaa ccagccaggc gaccagctgt gtttcgcgtg agttcagccc gtggagttcg
    29761 gcaaaatgca ctacatcctg agcaccgaga atggagtggt cgccgccgcg tcctttggcg
    29821 atatcgtgaa acagcgcggc gatgaaaatc agctcagttg acggcaggcg cggccagacg
    29881 tccacacaca acggatggcg ctggcgcgtt tcttcactgg caaaactctc cagtttcagc
    29941 atcacgcgga tagtatgttc atccaccgtg taggcgtgga acagatcaaa ctgcatctgc
    30001 ccgacgatat gcgaccattg cggcatatac gcgccgagca cgctatggcg atgcattggc
    30061 aatagcccgc gccgcaccgc tccggggtga cgcagaatgc tcaaaaacag ttttcgtgct
    30121 tccggaatat tacacagcgg ttgttgcaga tggcgacggg catggcgtaa ctggcgcagc
    30181 gtggtggagt aaatgccggt gatcgcactg ttgtgcacca tggtgtagaa catacgcaag
    30241 atggcttccg gctggcgcat aaatagtgtt tcatcacgca ggtcgattag cgtaccgcgt
    30301 agctgaaact catcgtcgat tggacgtggt ttttcgtcgg cgggaagggc gaggatggct
    30361 tcatcgaaca gttgcagcag catctggttg agttcactga cgcggcgtgt aacgcggaag
    30421 taatccttca tcatccgctc gaccggttcg ttaccttcac cactgtaatt cagacgctgg
    30481 gcgacgctaa gctggcgatc gaataacagg cgattatcgt aacggctgac gaccagatgc
    30541 agggcaaagc gaatacgcca caatatatgc agacattcgt ttaattccgc ccgctccgct
    30601 gaggttaaga agccaaaccc gaccatttca tccagcgatg ttgcgccaaa atgacggcgg
    30661 gccacccatt gcagagtgtg gatatcgcgc aagccgccag ggctgctttt gatgtctggt
    30721 tcaaggttgt agctggtgcc atggtaacgc tgatggcgct ggttctgttc ttcaactttc
    30781 gccgcgtaga acttgtcgga aggccagaat ccttcgctga aaatatgttt ttgcagttcg
    30841 aggaacagcg caacatcgcc aattaataag cgggattcga ttaaattggt ggcgacggtt
    30901 aaatccgata acccttccag catgcactct tcaagcgtgc gcacgctatg accgacttcc
    30961 agctttacat cccagagcag cgttaacagc tcgcccactt tttgcgcctg atcgtccggg
    31021 agctttttac ggcttaaaat cagtaaatcg acgtctgaaa gtggatgcag ctcgccacga
    31081 ccgtagccac cgacggcgac caatgccagg tcggcaatct ggctgaatcc cgcttcaatc
    31141 cataatcgtt gcaggagctg gtcgataaac tcggtgcgcg cctcaatcaa ctgttctgca
    31201 gagatcccat tgtcaaaggc atcacccagc caacgctgga aagtatcgat atgggctttt
    31261 atcccaccga cggttaattc atcacggggc cagacgcatg gattttgcgg ttgaccgggc
    31321 agggtgggga gagcggtgtt tgcgtactgt tctggaaggg tattcattgt gcgccaccca
    31381 taagattaaa ttatcgcatt aaaaaagccg gcattcgccg gcttcatctt attcgtcgtg
    31441 cgagattatc gccgggatgg tgtcatcctt gcgtagcgtc agaatttcgc agccgttatc
    31501 agtcaccaca atagtatgct catattgtgc agacaagctg cgatctttgg tttttaccgt
    31561 ccagccatct ttcatggtgc ggatctcttt tttacccgcg ttgaccattg gctcgatggt
    31621 gaacgtcatc ccaggtttca gtacgacgtt ggtttcacgg gagtcatagt gcagcacctg
    31681 cggttcttca tggaagccgc gaccaatacc gtgtccgcaa tattcacgaa cgacggagaa
    31741 gccttctgct tcgacaaatt tctgaatcgc cgcaccgatt tcgcgcagat taatgcctgg
    31801 ttttaccatg cgtagcgcca ggtacaggct ttcttgcgtg atgcggcaca gacgttcgcc
    31861 catgatggtc ggcttaccga cgataaacat tttcgaggta tcgccgtgga aaccatcttt
    31921 gattacggtg acatcaatgt taacgatatc gccatctttc agcagcttag catcgtccgg
    31981 gataccgtgg cacaccactt cattaataga gatgcaaacg gatttcggat agccgtgata
    32041 gccgaggcag gcagaaaccg cgtgttgttc attaacaatg taatcattac agatgcgatc
    32101 cagctcgccg gtgctgacgc ccggtttaac atacggttcg atcatctcca gcacttcggc
    32161 agccagtcgg ccagcgacgc gcattttttc gatatcttct ggggtcttga ttgagatagc
    32221 cattaattct gtccatcagc gtcggtgata ccgacaatat atatgtaagt gccgtcaatg
    32281 gtatcacacc cgggcaaatt gagaatcatt ctgaatttcg ccaaacgtgc cactgaaggt
    32341 tttctataat agaaaattcg acgtctgatg ctgtacacag cgccaacaat tattggtgtc
    32401 cacgacgtat ttgtggtata aagcgcgccg gacttccgat ccatttcgta tacacagact
    32461 ggacggaagc gacaatctca ctttgtgtaa caacacacac gtatcggcac atattccggg
    32521 gtgccctttg gggtcggtaa tatgggatac gtggaggcat aaccccaact tttatataga
    32581 ggttttaatc atggcaactg tttccatgcg cgacatgctc aaggctggtg ttcacttcgg
    32641 tcaccagacc cgttactgga acccgaaaat gaagccgttc atcttcggtg cgcgtaacaa
    32701 agttcacatc atcaaccttg agaaaactgt accgatgttc aacgaagctc tggctgaact
    32761 gaacaagatt gcttctcgca aaggtaaaat ccttttcgtt ggtactaaac gcgctgcaag
    32821 cgaagcggtg aaagacgctg ctctgagctg cgaccagttc ttcgtgaacc atcgctggct
    32881 gggcggtatg ctgactaact ggaaaaccgt tcgtcagtcc atcaaacgtc tgaaagacct
    32941 ggaaactcag tctcaggacg gtactttcga caagctgacc aagaaagaag cgctgatgcg
    33001 cactcgtgag ctggagaaac tggaaaacag cctgggcggt atcaaagaca tgggcggtct
    33061 gccggacgct ctgtttgtaa tcgatgctga ccacgaacac attgctatca aagaagcaaa
    33121 caacctgggt attccggtat ttgctatcgt tgataccaac tctgatccgg acggtgttga
    33181 cttcgttatc ccgggtaacg acgacgcaat ccgtgctgtg accctgtacc tgggcgctgt
    33241 tgctgcaacc gtacgtgaag gccgttctca ggatctggct tcccaggcgg aagaaagctt
    33301 cgtagaagct gagtaataag gcttgataac tcccccaaaa tagttcgagt tgcagaaagg
    33361 cggcaagctc gagaattccc gggagcttac atcagtaagt gaccgggatg agcgagcgaa
    33421 gataacgcat ctgcggcgcg aaatatgaag ggggagagcc cttatagacc aggtagtaca
    33481 cgtttggtta gggggcctgc atatggcccc ctttttcact tttatatctg tgcggtttaa
    33541 tgccgggcag atcacatctc cgaggatttt agaatggctg aaattaccgc atccctggta
    33601 aaagagctgc gtgagcgtac tggcgcaggc atgatggatt gcaaaaaagc actgactgaa
    33661 gctaacggcg acatcgagct ggcaatcgaa aacatgcgta agtccggtgc tattaaagca
    33721 gcgaaaaaag caggcaacgt tgctgctgac ggcgtgatca aaaccaaaat cgacggcaac
    33781 tacggcatca ttctggaagt taactgccag actgacttcg ttgcaaaaga cgctggtttc
    33841 caggcgttcg cagacaaagt tctggacgca gctgttgctg gcaaaatcac tgacgttgaa
    33901 gttctgaaag cacagttcga agaagaacgt gttgcgctgg tagcgaaaat tggtgaaaac
    33961 atcaacattc gccgcgttgc tgcgctggaa ggcgacgttc tgggttctta tcagcacggt
    34021 gcgcgtatcg gcgttctggt tgctgctaaa ggcgctgacg aagagctggt taaacacatc
    34081 gctatgcacg ttgctgcaag caagccagaa ttcatcaaac cggaagacgt atccgctgaa
    34141 gtggtagaaa aagaatacca ggtacagctg gatatcgcga tgcagtctgg taagccgaaa
    34201 gaaatcgcag agaaaatggt tgaaggccgc atgaagaaat tcaccggcga agtttctctg
    34261 accggtcagc cgttcgttat ggaaccaagc aaaactgttg gtcagctgct gaaagagcat
    34321 aacgctgaag tgactggctt catccgcttc gaagtgggtg aaggcatcga gaaagttgag
    34381 actgactttg cagcagaagt tgctgcgatg tccaagcagt cttaattatc aaaaaggagc
    34441 cgcctgaggg cggcttcttt ttgtgcccat cttgtaaatt cagctaaccc ttgtggggct
    34501 gcgctgaaaa gcgacgtaca atgtcgctag tattaattca tttcaatcgt tgacagtctc
    34561 aggaaagaaa catggctacc aatgcaaaac ccgtctataa acgcattctg cttaagttga
    34621 gtggcgaagc tctgcagggc actgaaggct tcggtattga tgcaagcata ctggatcgta
    34681 tggctcagga aatcaaagaa ctggttgaac tgggtattca ggttggtgtg gtgattggtg
    34741 ggggtaacct gttccgtggc gctggtctgg cgaaagcggg tatgaaccgc gttgtgggcg
    34801 accacatggg gatgctggcg accgtaatga acggcctggc aatgcgtgat gcactgcacc
    34861 gcgcctatgt gaacgctcgt ctgatgtccg ctattccatt gaatggcgtg tgcgacagct
    34921 acagctgggc agaagctatc agcctgttgc gcaacaaccg tgtggtgatc ctctccgccg
    34981 gtacaggtaa cccgttcttt accaccgact cagcagcttg cctgcgtggt atcgaaattg
    35041 aagccgatgt ggtgctgaaa gcaaccaaag ttgacggcgt gtttaccgct gatccggcga
    35101 aagatccaac cgcaaccatg tacgagcaac tgacttacag cgaagtgctg gaaaaagagc
    35161 tgaaagtcat ggacctggcg gccttcacgc tggctcgtga ccataaatta ccgattcgtg
    35221 ttttcaatat gaacaaaccg ggtgcgctgc gccgtgtggt aatgggtgaa aaagaaggga
    35281 ctttaatcac ggaataattc ccgtgatgga taaataaggg taagattccg cgtaagtatc
    35341 gcgggggcgt aagtctggtt ataaggcgtt attgttgcag gcagtttggt cacggccagc
    35401 gcgcagcaac cggagcgtac aaaagtacgt gaggatggcg agcactgccc ggggccaaaa
    35461 tggcaaataa aatagcctaa taatccagac gattacccgt aatatgttta atcagggcta
    35521 tacttagcac acttccactg tgtgtgactg tctggtctga ctgagacaag ttttcaagga
    35581 ttcgtaacgt gattagcgat atcagaaaag atgctgaagt acgcatggac aaatgcgtag
    35641 aagcgttcaa aacccaaatc agcaaaatac gcacgggtcg tgcttctccc agcctgctgg
    35701 atggcattgt cgtggaatat tacggcacgc cgacgccgct gcgtcagctg gcaagcgtaa
    35761 cggtagaaga ttcccgtaca ctgaaaatca acgtgtttga tcgttcaatg tctccggccg
    35821 ttgaaaaagc gattatggcg tccgatcttg gcctgaaccc gaactctgcg ggtagcgaca
    35881 tccgtgttcc gctgccgccg ctgacggaag aacgtcgtaa agatctgacc aaaatcgttc
    35941 gtggtgaagc agaacaagcg cgtgttgcag tacgtaacgt gcgtcgtgac gcgaacgaca
    36001 aagtgaaagc actgttgaaa gataaagaga tcagcgaaga cgacgatcgc cgttctcagg
    36061 acgatgtaca gaaactgact gatgctgcaa tcaagaaaat tgaagcggcg ctggcagaca
    36121 aagaagcaga actgatgcag ttctgatttc ttgaacgaca aaaacgccgc tcagtagatc
    36181 cttgcggatc ggctggcggc gttttgcttt ttattctgtc tcaactctgg atgtttcatg
    36241 aagcaactca ccattctggg ctcgaccggc tcgattggtt gcagcacgct ggacgtggtg
    36301 cgccataatc ccgaacactt ccgcgtagtt gcgctggtgg caggcaaaaa tgtcactcgc
    36361 atggtagaac agtgcctgga attctctccc cgctatgccg taatggacga tgaagcgagt
    36421 gcgaaacttc ttaaaacgat gctacagcaa cagggtagcc gcaccgaagt cttaagtggg
    36481 caacaagccg cttgcgatat ggcagcgctt gaggatgttg atcaggtgat ggcagccatt
    36541 gttggcgctg ctgggctgtt acctacgctt gctgcgatcc gcgcgggtaa aaccattttg
    36601 ctggccaata aagaatcact ggttacctgc ggacgtctgt ttatggacgc cgtaaagcag
    36661 agcaaagcgc aattgttacc ggtcgatagc gaacataacg ccatttttca gagtttaccg
    36721 caacctatcc agcataatct gggatacgct gaccttgagc aaaatggcgt ggtgtccatt
    36781 ttacttaccg ggtctggtgg ccctttccgt gagacgccat tgcgcgattt ggcaacaatg
    36841 acgccggatc aagcctgccg tcatccgaac tggtcgatgg ggcgtaaaat ttctgtcgat
    36901 tcggctacca tgatgaacaa aggtctggaa tacattgaag cgcgttggct gtttaacgcc
    36961 agcgccagcc agatggaagt gctgattcac ccgcagtcag tgattcactc aatggtgcgc
    37021 tatcaggacg gcagtgttct ggcgcagctg ggggaaccgg atatgcgtac gccaattgcc
    37081 cacaccatgg catggccgaa tcgcgtgaac tctggcgtga agccgctcga tttttgcaaa
    37141 ctaagtgcgt tgacatttgc cgcaccggat tatgatcgtt atccatgcct gaaactggcg
    37201 atggaggcgt tcgaacaagg ccaggcagcg acgacagcat tgaatgccgc aaacgaaatc
    37261 accgttgctg cttttcttgc gcaacaaatc cgctttacgg atatcgctgc gttgaattta
    37321 tccgtactgg aaaaaatgga tatgcgcgaa ccacaatgtg tggacgatgt gttatctgtt
    37381 gatgcgaacg cgcgtgaagt cgccagaaaa gaggtgatgc gtctcgcaag ctgaggataa
    37441 tccggctaca gagagtcgcg ctatttgtta gcgtagggct tcagtgatat agtctgcgcc
    37501 atctgatcgt aagtagttgg ctttataagg tcaggtatgc cgtggtttta cacggctttt
    37561 ttttgtatag gcttcagtat tcctgagtac cgtaaaccct gtcagggaat aaaaaacgcg
    37621 tgatgttgtc tgctactcaa ccacttagcg aaaaattgcc agcgcatggc tgccgtcatg
    37681 ttgcgatcat tatggacggc aatggccgct gggcaaaaaa gcaagggaag attcgtgcct
    37741 ttgggcataa agccggggca aaatccgtcc gccgggctgt ctcttttgcg gccaacaacg
    37801 gtattgaggc gttaacgctg tatgccttta gtagtgaaaa ctggaaccga ccagcgcagg
    37861 aagtcagtgc gttaatggaa ctgtttgtgt gggcgctcga tagcgaagta aaaagtctgc
    37921 accgacataa cgtgcgtctg cgtattattg gcgataccag tcgctttaac tcgcgtttgc
    37981 aagaacgtat tcgtaaatct gaagcgctaa cagccgggaa taccggtctg acgctgaata
    38041 ttgcggcgaa ctacggtgga cgttgggata tagtccaggg agtcaggcaa ctggctgaaa
    38101 aggtgcagca aggaaacctg caaccagatc agatagatga agagatgcta aaccagcatg
    38161 tctgtatgca tgaactggcc cctgtagatt tagtaattag gactgggggg gagcatcgca
    38221 ttagtaactt tttgctttgg caaattgcct atgccgaact ttactttaca gatgttctct
    38281 ggcccgattt cgatgaacaa gactttgaag gggcgttaaa tgcctttgct aatcgagagc
    38341 gtcgtttcgg cggcaccgag cccggtgatg aaacagcctg atgggggtcg cttttgctga
    38401 agtatcgcct gatatctgct tttgtgttaa tacccgtcgt catcgcggcg ttgtttctgt
    38461 tgccgccggt ggggttcgcc attgtaacgc tggtggtctg catgctggca gcgtgggaat
    38521 ggggacagct tagcggtttt accactcgtt cgcagcgagt atggttggcg gtgttatgcg
    38581 ggttattgtt ggcgctgatg ctttttctgt tgccggaata tcaccgaaat attcatcaac
    38641 cgctggttga aatctcactt tgggcttcgc tgggttggtg gattgtcgcg ctattgctgg
    38701 tgctgtttta cccaggttcc gcagcaatct ggcgtaactc taaaacattg cgccttattt
    38761 ttggcgtgct aaccattgtt cccttcttct ggggcatgct ggcgttacgg gcctggcact
    38821 atgacgagaa tcattacagt ggcgcaatat ggctgctcta tgtcatgatc ctggtatggg
    38881 gcgctgactc cggcgcatat atgtttggca aattgtttgg taaacataag ctggcaccga
    38941 aggtttctcc gggtaaaacc tggcaaggct ttatcggtgg actcgctact gcagcggtaa
    39001 tctcatgggg ttatggcatg tgggcgaatc tcgacgtcgc tcccgtcacc ttactcattt
    39061 gctctattgt cgcagcgtta gcctcagtgc tcggcgatct gaccgagagt atgtttaagc
    39121 gtgaagcagg aattaaggac agcggtcatt taattccagg acacggtggt attttagatc
    39181 gtattgatag cctgacggct gcggtaccgg tctttgcttg cttgttgtta ctggtattca
    39241 ggacgcttta acggaaggta atatgctgag ttttctctgg gatttggctt cgttcatcgt
    39301 tgcactgggt gtacttatca ccgtgcatga atttggtcat ttctgggttg cccggcgttg
    39361 tggtgttcgc gttgagcgtt tctcaatagg gtttggtaag gcgctctggc ggcgaactga
    39421 taagctcggc accgaatatg ttatcgccct gatcccgttg ggcggttatg tcaaaatgct
    39481 ggatgagcgc gcagaaccgg tcgttccgga actccgccac catgccttca ataataaatc
    39541 tgtcggccaa cgagcggcga ttattgccgc aggtccggtt gcaaacttca tttttgctat
    39601 ctttgcctac tggctggttt ttattattgg tgtgcctggc gtacgtccgg tggttggcga
    39661 aatagcagcc aattcgatag ctgcggaagc acaaattgca ccaggtacgg aactaaaagc
    39721 cgtagatggt atcgaaacgc ctgattggga tgccgtgcgt ttgcagttgg tcgataaaat
    39781 tggcgatgaa agcaccacca ttacagtagc gccatttggc agcgaccaac ggcgggatgt
    39841 aaagctcgat ttacgtcact gggcgtttga gcctgataaa gaagatccgg tatcttcgct
    39901 ggggattcgt cctcgtgggc cgcaaattga acctgtactg gaaaatgtgc agccaaactc
    39961 ggcggcaagc aaggcaggtt tgcaagcagg cgacaggatc gttaaagtcg atggtcagcc
    40021 cttaacgcag tgggtgacct ttgtgatgct tgtccgggat aacccgggta aatccttagc
    40081 gttagaaatc gaaaggcagg ggagtccctt gtctttgaca ttaatcccgg agagtaaacc
    40141 gggtaatggt aaagcgattg gttttgtcgg tattgagccg aaagtcattc ctttgccaga
    40201 tgagtataaa gttgtacgcc agtatgggcc gttcaacgcc atcgtcgaag ccacggacaa
    40261 aacgtggcag ctgatgaagc tgacggtcag tatgctggga aaattgatca ccggtgatgt
    40321 gaaactgaac aacctcagtg ggccgatctc tatcgccaag ggggctggga tgacagcgga
    40381 actcggggtt gtttattacc tgccgtttct tgcgcttatt agcgtgaact tagggataat
    40441 taacctgttt ccgttgcccg tacttgacgg ggggcatctg ctgttccttg cgatcgaaaa
    40501 gatcaagggc ggaccggtat ccgagcgggt tcaagacttt tgttatcgca ttggctcgat
    40561 tctgctggtg ctgttaatgg ggcttgcact tttcaatgat ttctctcggt tatgagagtt
    40621 agttaggaag aacgcataat aacgatggcg atgaaaaagt tgctcatagc gtcgctgctg
    40681 tttagcagcg ccaccgtata cggtgctgaa gggttcgtag tgaaagatat tcatttcgaa
    40741 ggccttcagc gtgtcgccgt tggtgcggcc ctcctcagta tgccggtgcg cacaggcgac
    40801 acggttaatg atgaagatat cagtaatacc attcgcgctc tgtttgctac cggcaacttt
    40861 gaggatgttc gcgtccttcg tgatggtgat acccttctgg ttcaggtaaa agaacgtccg
    40921 accattgcca gcattacttt ctccggtaac aaatcggtga aagatgacat gctgaagcaa
    40981 aacctcgagg cttctggtgt gcgtgtgggc gaatccctcg atcgcaccac cattgccgat
    41041 atcgagaaag gtctggaaga cttctactac agcgtcggta aatatagcgc cagcgtaaaa
    41101 gctgtcgtga ccccgctgcc gcgcaaccgt gttgacctaa aactggtgtt ccaggaaggt
    41161 gtgtcagctg aaatccagca aattaacatt gttggtaacc atgctttcac caccgacgaa
    41221 ctgatctctc atttccaact gcgtgacgaa gtgccgtggt ggaacgtggt aggcgatcgt
    41281 aaataccaga aacagaaact ggcgggcgac cttgaaaccc tgcgcagcta ctatctggat
    41341 cgcggttatg cccgtttcaa catcgactct acccaggtca gtctgacgcc agataaaaaa
    41401 ggtatttacg tcacggtgaa catcaccgaa ggcgatcagt acaagctttc tggcgttgaa
    41461 gtgagcggca accttgccgg gcactccgct gaaattgagc agctgactaa gatcgagccg
    41521 ggtgagctgt ataacggcac caaagtgacc aagatggaag atgacatcaa aaagcttctc
    41581 ggtcgctatg gttatgccta tccgcgcgta cagtcgatgc ccgaaattaa cgatgccgac
    41641 aaaaccgtta aattacgtgt gaacgttgat gcgggtaacc gtttctacgt gcgtaagatc
    41701 cgttttgaag gtaacgatac ctcgaaagat gccgtcctgc gtcgcgaaat gcgtcagatg
    41761 gaaggtgcat ggctggggag cgatctggtc gatcagggta aggagcgtct gaatcgtctg
    41821 ggcttctttg aaactgtcga taccgatacc caacgtgttc cgggtagccc ggaccaggtt
    41881 gatgtcgtct acaaggtaaa agagcgcaac accggtagct tcaactttgg tattggttac
    41941 ggtactgaaa gtggcgtgag cttccaggct ggtgtgcagc aggataactg gttaggtaca
    42001 ggttatgctg ttggtatcaa cgggaccaaa aacgattacc agacctatgc tgaactgtcg
    42061 gtaaccaacc cgtacttcac cgtagatggc gtaagcctcg gtggtcgtct cttctataat
    42121 gacttccagg cagatgacgc cgacctgtcc gactatacca acaagagtta tggtacagac
    42181 gtgacgttgg gcttcccgat taacgaatat aactcgctgc gtgcaggtct gggttatgta
    42241 cataactccc tgtccaacat gcagcctcag gttgcgatgt ggcgttatct gtactctatg
    42301 ggtgaacatc cgagcacctc tgatcaggat aacagcttca aaacggacga cttcacgttc
    42361 aactatggtt ggacctataa caagcttgac cgtggttact tcccgacaga tggttcacgt
    42421 gtcaacctga ccggtaaagt gaccattcct ggatcggata acgaatacta caaagtgacg
    42481 ttagacacgg cgacttatgt gccgatcgat gacgatcaca aatgggttgt tctggggcgt
    42541 acccgctggg gttatggtga tggtttaggc ggcaaagaga tgccgttcta cgagaacttc
    42601 tatgccggtg gttccagcac cgtgcgtggc ttccagtcca ataccattgg tccgaaagca
    42661 gtttacttcc cgcatcaggc cagtaattat gatccggact atgattacga atgtgcgact
    42721 caggacggcg cgaaagacct gtgtaaatcg gatgatgctg taggcggtaa cgccatggcg
    42781 gttgccagcc tcgagttcat caccccgacg ccgtttatta gcgataagta tgctaactcg
    42841 gttcgtactt ccttcttctg ggatatgggt accgtttggg atacaaactg ggattccagc
    42901 caatattctg gatatccgga ctatagtgat ccaagcaata tccgtatgtc tgcgggtatc
    42961 gcattacaat ggatgtcccc attggggccg ttggtgttct cctacgccca gccgttcaaa
    43021 aagtacgatg gagacaaggc agaacagttc cagtttaaca tcggtaaaac ctggtaagtg
    43081 ttctccacaa aggaatgtag tggtagtgta gcgatgactt taggcgatca atataagatc
    43141 gccgggccac gcaaagaact gcaccctccg gtgcaaatgg gatggtaagg agtttattgt
    43201 gaaaaagtgg ttattagctg caggtctcgg tttagcactg gcaacttctg ctcaggcggc
    43261 tgacaaaatt gcaatcgtca acatgggcag cctgttccag caggtagcgc agaaaaccgg
    43321 tgtttctaac acgctggaaa atgagttcaa aggccgtgcc agcgaactgc agcgtatgga
    43381 aaccgatctg caggctaaaa tgaaaaagct gcagtccatg aaagcgggca gcgatcgcac
    43441 taagctggaa aaagacgtga tggctcagcg ccagactttt gctcagaaag cgcaggcttt
    43501 tgagcaggat cgcgcacgtc gttccaacga agaacgcggc aaactggtta ctcgtatcca
    43561 gactgctgtg aaatccgttg ccaacagcca ggatatcgat ctggttgttg atgcaaacgc
    43621 cgttgcttac aacagcagcg atgtaaaaga catcactgcc gacgtactga aacaggttaa
    43681 ataagtaatg ccttcaattc gactggctga tttagcgcag cagttggatg cagaactaca
    43741 cggtgatggc gatatcgtca tcaccggcgt tgcgtccatg caatctgcac aaacaggtca
    43801 cattacgttc atggttaacc caaaataccg tgagcattta ggcttgtgcc aggcgtccgc
    43861 ggttgtcatg acccaggacg atcttccttt cgcgaaaagt gccgcactgg tagtgaagaa
    43921 tccctacctg acttacgcgc gcatggcgca aattttagat accacgccgc agcccgcgca
    43981 gaacattgca cccagtgcgg tgatcgacgc gacggcgaag ctgggtaaca acgtatcgat
    44041 tggcgctaac gcggtgattg agtccggcgt tgaactgggc gataacgtga ttatcggtgc
    44101 cggttgcttc gtaggtaaaa acagcaaaat cggtgcaggt tcgcgtctct gggcgaacgt
    44161 aaccatttac catgagatcc agatcggtca gaattgcctg atccagtccg gaacagtggt
    44221 aggcgcagac ggctttggtt atgccaacga tcgtggtaac tgggtgaaga tcccacagat
    44281 tggtcgcgta attattggcg atcgcgtgga gatcggtgcc tgcacaacca tcgatcgcgg
    44341 cgcgctggat gacactatta ttggcaatgg cgtgatcatt gataaccagt gccagattgc
    44401 acataacgtc gtgattggcg acaatacggc ggttgccggt ggcgtcatta tggcgggcag
    44461 cctgaaaatt ggtcgttact gcatgatcgg cggagccagc gtaatcaacg ggcatatgga
    44521 aatatgcgac aaagtgacgg ttacgggcat gggtatggtg atgcgtccca tcactgaacc
    44581 aggcgtctat tcctcaggca ttccgctgca acccaacaaa gtctggcgca aaaccgctgc
    44641 actggtgatg aacattgatg acatgagcaa gcgtctgaaa tcgcttgagc gcaaggttaa
    44701 tcaacaagac taacgttcca tcttttgttc gccaaacttt acggcctgtc tcattcttac
    44761 gattgcggca ggccgtgtta ttattgtcgt ttcttatatt ttgacaggaa gagtatcttg
    44821 actactaaca ctcatactct gcagattgaa gagattttag aacttctgcc gcaccgtttc
    44881 ccgttcttac tggtggatcg cgtgctggat tttgaagaag gtcgttttct gcgcgcagta
    44941 aaaaatgtct ctgtcaatga gccattcttc cagggccatt tccctggaaa accgattttc
    45001 ccgggtgtgc tgattctgga agcaatggca caggcaacag gtattctggc gtttaaaagc
    45061 gtaggaaaac tggaaccggg tgagctgtac tacttcgctg gtattgacga agcgcgcttc
    45121 aagcgcccgg tcgtgcctgg cgatcaaatg atcatggaag tcactttcga aaaaacgcgc
    45181 cgcggcctga cccgttttaa aggggttgct ctggtcgatg gtaaagtagt ttgcgaagca
    45241 acgatgatgt gtgctcgtag ccgggaggcc tgatacgtga ttgataaatc cgcctttgtg
    45301 catccaaccg ccattgtgga agagggcgcg tcaattggcg cgaacgcaca cattggtcct
    45361 ttttgtatcg ttggacccca tgtcgaaatt ggtgagggta ccgtactgaa atctcacgtt
    45421 gtcgtgaatg gtcatactaa aattggccgc gataatgaga tttatcagtt cgcctccatc
    45481 ggcgaagtta accaggatct gaaatatgct ggcgaaccga cccgtgtgga aatcggcgat
    45541 cgtaaccgca ttcgcgaaag cgtcaccatt catcgtggca cagtccaggg cggtggattg
    45601 acgaaggtgg gcagcgacaa cttactgatg atcaacgcgc acattgcgca cgattgtacg
    45661 gtaggtaacc gctgtattct cgccaacaac gcaacgctgg cgggtcacgt atcggttgac
    45721 gacttcgcga tcatcggcgg catgaccgca gtccatcagt tctgcatcat tggtgcgcac
    45781 gtgatggttg gcggctgctc cggtgtggcg caggacgtcc ctccttatgt cattgcgcag
    45841 ggtaaccacg caacgccgtt cggtgtcaat atcgaagggc tgaagcgccg cggattcagc
    45901 cgtgaggcga ttaccgctat ccgcaatgcg tataagctga tttatcgtag cggtaaaacg
    45961 ctcgatgaag tgaaaccgga aattgctgaa ctggcggaaa catatccgga agtgaaagcc
    46021 tttaccgatt tctttgcacg ctcaacgcgc ggtctgattc gttaatgact gaacagcgtc
    46081 cattaacgat tgccctggtc gccggagaaa cctccggcga tatcctgggg gccggtttaa
    46141 tccgcgctct gaaagaacat gtgcccaacg cccgctttgt tggtgttgcc gggccacgaa
    46201 tgcaggctga aggctgcgaa gcctggtacg aaatggaaga actggcggtg atgggcattg
    46261 ttgaagtgct cggtcgtctg cgtcgcttac tgcatattcg tgccgatctg acaaagcgtt
    46321 ttggcgaact gaagccagat gtttttgttg gtattgatgc gcctgacttc aatattactc
    46381 ttgaaggtaa cctcaaaaag cagggtatca aaaccattca ttacgtcagt ccgtcagtct
    46441 gggcgtggcg acagaaacgt gttttcaaaa taggcagagc caccgatctg gtgctcgcat
    46501 ttctgccttt cgaaaaagcg ttttatgaca aatacaacgt accgtgccgc tttatcggtc
    46561 ataccatggc tgatgccatg ccattagatc cagataaaaa tgccgcccgt gatgtgctgg
    46621 ggatccctca cgatgcccac tgcctggcgt tgctaccggg gagccgtggt gcagaagttg
    46681 aaatgcttag tgccgatttc ctgaaaacgg cccagctttt gcgccagaca tatccggatc
    46741 tcgaaatcgt ggtgccactg gtgaatgcca aacgccgcga gcagtttgaa cgcatcaaag
    46801 ctgaagtcgc gccagacctt tcagttcatt tgctggatgg gatgggccgt gaggcgatgg
    46861 tcgccagcga tgcggcgcta ctggcgtcgg gtacggcagc cctggagtgt atgctggcga
    46921 aatgcccgat ggtggtggga tatcgcatga agccttttac cttctggttg gcgaagcggc
    46981 tggtgaaaac tgattatgtc tcgctgccaa atctgctggc gggcagagag ttagtcaaag
    47041 aattattgca ggaagagtgt gagccgcaaa aactggctgc ggcgctgtta ccgctgttgg
    47101 cgaacgggaa aaccagccac gcgatgcacg ataccttccg tgaactgcat cagcagatcc
    47161 gctgcaatgc cgatgagcag gcggcacaag ccgttctgga gttagcacaa tgatcgaatt
    47221 tgtttatccg cacacgcagc tggttgcggg tgtggatgaa gtcggacgcg ggccgttagt
    47281 tggcgcggtc gtcaccgctg cggtgatcct tgacccggcg cgcccgattg ccgggctgaa
    47341 tgattccaaa aagctgagcg aaaaacgccg tctggcgctc tatgaagaga tcaaagagaa
    47401 agcgttgagc tggagtctgg gccgcgcgga accccacgaa atcgacgagc tgaacattct
    47461 tcatgcgacc atgctggcga tgcagcgtgc cgtcgctggg ctgcatattg cgccggaata
    47521 tgtgttgatt gatggtaacc gctgcccgaa attaccgatg cctgcgatgg ctgtggtgaa
    47581 aggcgatagc cgcgtaccgg aaatcagtgc cgcgtctatc ctggcgaaag tgacgcgtga
    47641 cgccgaaatg gcggcgctgg atattgtttt cccgcaatat ggttttgccc aacacaaagg
    47701 gtacccaacc gcttttcatc tggaaaaact ggctgaacac ggcgcgaccg aacaccatcg
    47761 gcgcagcttt gggcctgtca aacgcgcact gggacttgcg tcctgattct tgtgtcgaga
    47821 ttaagtaaac cggaatctga agatgtctga accacgtttc gtacacctgc gggtgcacag
    47881 cgactactcg atgatcgatg gcctggccaa aaccgcaccg ttggtaaaaa aggcggcggc
    47941 gttgggtatg ccagcactgg cgatcaccga tttcaccaac ctttgtggtc tggtgaagtt
    48001 ctacggagcg ggacatggcg cagggattaa gcctatcgtc ggggcagatt ttaacgtcca
    48061 gtgcgacctg ctgggtgatg agttaaccca cctgacggta ctggcggcga acaataccgg
    48121 ctatcagaat ctgacgttgc tgatctcaaa agcgtatcag cgcgggtacg gtgccgccgg
    48181 gccgatcatc gatcgcgact ggcttatcga attaaacgaa gggttgatcc ttctttccgg
    48241 cggacgcatg ggcgacgtcg gacgcagtct tttgcgtggt aacagcgcgc tggtagatga
    48301 gtgtgtcgcg ttttatgaag aacacttccc ggatcgctat tttctcgagc tgatccgcac
    48361 cggcaggccg gatgaagaaa gctatctgca cgcggcggtg gaactggcgg aagcgcgcgg
    48421 tttgcccgtc gtggcgacca acgacgtgcg ctttatcgac agcagcgact ttgacgcaca
    48481 cgaaatccgc gtcgcgatcc acgacggctt taccctcgac gatcctaaac gcccgcgtaa
    48541 ctattcgccg cagcaatata tgcgtagcga agaggagatg tgtgagctgt ttgccgacat
    48601 ccccgaagcc cttgccaaca ccgttgagat cgccaaacgc tgtaacgtaa ccgtgcgtct
    48661 tggtgaatac ttcctgccgc agttcccgac cggggacatg agcaccgaag attatctggt
    48721 caagcgtgca aaagagggcc tggaagagcg tctggccttt ttattccctg atgaggaaga
    48781 acgtcttaag cgccgcccgg aatatgacga acgtctggag actgaacttc aggttatcaa
    48841 ccagatgggc ttcccgggct acttcctcat cgttatggaa tttatccagt ggtcgaaaga
    48901 taacggcgta ccggtagggc caggccgtgg ctccggtgcg ggttcactgg tggcctacgc
    48961 gctgaaaatc accgacctcg atccgctgga atttgacctg ctgttcgaac gtttccttaa
    49021 cccggaacgt gtctccatgc ctgacttcga cgttgacttc tgtatggaga aacgcgatca
    49081 ggttatcgag cacgtagcgg acatgtacgg tcgtgatgcg gtatcgcaga tcatcacctt
    49141 cggtacaatg gcggcgaaag cggtgatccg cgacgtaggc cgcgtgctgg ggcatccgta
    49201 cggctttgtc gatcgtatct cgaaactgat cccgcccgat ccggggatga cgctggcgaa
    49261 agcgtttgaa gccgagccgc agctgccgga aatctacgaa gcggatgaag aagttaaggc
    49321 gctgatcgac atggcgcgca aactggaagg ggtcacccgt aacgccggta agcacgccgg
    49381 tggggtggtt atcgcgccga ccaaaattac cgattttgcg ccgctttact gcgatgaaga
    49441 gggcaaacat ccggtcaccc agtttgataa aagcgacgtt gaatacgccg gactggtgaa
    49501 gttcgacttc cttggtttgc gtacgctcac catcatcaac tgggcgctgg agatgatcaa
    49561 caagcggcgg gcgaagaatg gcgagccgcc gctggatatc gctgcgatcc cgctggatga
    49621 taagaaaagc ttcgacatgc tgcaacgctc ggaaaccacg gcggtattcc agcttgaatc
    49681 gcgcggcatg aaggacctga tcaagcgtct acaacctgac tgcttcgaag atatgatcgc
    49741 cctagtggca ctgttccgcc ccggtccgtt gcaatcaggg atggtggata actttatcga
    49801 ccgtaaacat ggtcgtgaag agatctccta tccggacgta cagtggcagc atgaaagcct
    49861 gaaaccggta ctggagccaa cctacggcat tatcctgtat caggaacagg tcatgcagat
    49921 tgcgcaggtg ctttctggtt ataccctcgg tggcgcggat atgctgcgtc gtgcgatggg
    49981 taagaaaaag ccggaagaga tggctaagca acgttctgta tttgctgaag gtgcagaaaa
    50041 gaacggaatc aacgctgaac tggcgatgaa aatcttcgac ctggtggaga aattcgctgg
    50101 ttacggattt aacaaatcgc actctgcggc ctatgctttg gtgtcatatc aaacgttatg
    50161 gctgaaagcg cactatcctg cggagtttat ggcggcggta atgaccgccg atatggacaa
    50221 caccgagaag gtggtgggtc tggtggatga gtgctggcgg atggggctga aaatcctgcc
    50281 accagatata aactccggtc tttaccattt ccacgtcaac gacgacggcg aaatcgtgta
    50341 tggtattggc gcgatcaaag gggtcggtga aggtccgatt gaggccatca tcgaagcccg
    50401 taataaaggc ggctacttcc gcgaactgtt tgatctctgc gcccgtaccg acaccaaaaa
    50461 gttgaaccgt cgcgtgctgg aaaaactgat catgtccggg gcgtttgacc gtcttgggcc
    50521 acatcgcgca gcgctgatga actcgctggg cgatgcgtta aaagcggcag atcaacacgc
    50581 gaaagcggaa gctatcggtc aggccgatat gttcggcgtg ctggccgaag agccggaaca
    50641 aattgaacaa tcctacgcca gctgccaacc gtggccggag caggtggtat tagatgggga
    50701 acgtgaaacg ttaggcctgt acctgaccgg acaccctatc aaccagtatt taaaagagat
    50761 tgagcgttat gtcggaggcg taaggctgaa agacatgcac ccgacagaac gtggtaaagt
    50821 catcacggct gcggggctcg ttgttgccgc gcgggttatg gtcaccaagc gcggcaatcg
    50881 tatcggtatc tgcacgctgg atgaccgttc cgggcggctg gaagtgatgt tgtttactga
    50941 cgccctggat aaataccagc aattgctgga aaaagaccgc atacttatcg tcagcggaca
    51001 ggtcagcttt gatgacttca gcggtgggct taaaatgacc gctcgcgaag tgatggatat
    51061 tgacgaagcc cgggaaaaat atgctcgcgg gcttgctatc tcgctgacgg acaggcaaat
    51121 tgatgaccag cttttaaacc gactccgtca gtctctggaa ccccaccgct ctgggacaat
    51181 tccagtacat ctctactatc agagggcgga tgcacgcgcg cggttgcgtt ttggcgcgac
    51241 gtggcgtgtc tctccgagcg atcgtttatt aaacgatctc cgtggcctca ttggttcgga
    51301 gcaggtggaa ctggagtttg actaatacag gaatactatg agtctgaatt tccttgattt
    51361 tgaacagccg attgcagagc tggaagcgaa aatcgattct ctgactgcgg ttagccgtca
    51421 ggatgagaaa ctggatatta acatcgatga agaagtgcat cgtctgcgtg aaaaaagcgt
    51481 agaactgaca cgtaaaatct tcgccgatct cggtgcatgg cagattgcgc aactggcacg
    51541 ccatccacag cgtccttata ccctggatta cgttcgcctg gcatttgatg aatttgacga
    51601 actggctggc gaccgcgcgt atgcagacga taaagctatc gtcggtggta tcgcccgtct
    51661 cgatggtcgt ccggtgatga tcattggtca tcaaaaaggt cgtgaaacca aagaaaaaat
    51721 tcgccgtaac tttggtatgc cagcgccaga aggttaccgc aaagcactgc gtctgatgca
    51781 aatggctgaa cgctttaaga tgcctatcat cacctttatc gacaccccgg gggcttatcc
    51841 tggcgtgggc gcagaagagc gtggtcagtc tgaagccatt gcacgcaacc tgcgtgaaat
    51901 gtctcgcctc ggcgtaccgg tagtttgtac ggttatcggt gaaggtggtt ctggcggtgc
    51961 gctggcgatt ggcgtgggcg ataaagtgaa tatgctgcaa tacagcacct attccgttat
    52021 ctcgccggaa ggttgtgcgt ccattctgtg gaagagcgcc gacaaagcgc cgctggcggc
    52081 tgaagcgatg ggtatcattg ctccgcgtct gaaagaactg aaactgatcg actccatcat
    52141 cccggaacca ctgggtggtg ctcaccgtaa cccggaagcg atggcggcat cgttgaaagc
    52201 gcaactgctg gcggatctgg ccgatctcga cgtgttaagc actgaagatt taaaaaatcg
    52261 tcgttatcag cgcctgatga gctacggtta cgcgtaattc gcaaaagttc tgaaaaaggg
    52321 tcacttcggt ggcccttttt tatcgccacg gtttgagcag gctatgatta aggaaggatt
    52381 ttccaggagg aacacatgaa catcattgcc attatgggac cgcatggcgt cttttataaa
    52441 gatgagccca tcaaagaact ggagtcggcg ctggtggcgc aaggctttca gattatctgg
    52501 ccacaaaaca gcgttgattt gctgaaattt atcgaacata accctcgaat ttgcggcgtg
    52561 atttttgact gggatgagta cagtctcgat ttatgtagcg atatcaatca gcttaatgaa
    52621 tatctcccgc tttatgcctt catcaacacc cactcgacga tggatgtcag cgtgcaggat
    52681 atgcggatgg cgctctggtt ttttgaatat gcgctggggc aggcggaaga tatcgccatt
    52741 cgtatgcgtc agtacaccga cgaatatctt gataacatta caccgccgtt cacgaaagcc
    52801 ttgtttacct acgtcaaaga gcggaagtac accttttgta cgccggggca tatgggcggc
    52861 accgcatatc aaaaaagccc ggttggctgt ctgttttatg attttttcgg cgggaatact
    52921 cttaaggctg atgtctctat ttcggtcacc gagcttggtt cgttgctcga ccacaccggg
    52981 ccacacctgg aagcggaaga gtacatcgcg cggacttttg gcgcggaaca gagttatatc
    53041 gttaccaacg gaacatcgac gtcgaacaaa attgtgggta tgtacgccgc gccatccggc
    53101 agtacgctgt tgatcgaccg caattgtcat aaatcgctgg cgcatctgtt gatgatgaac
    53161 gatgtagtgc cagtctggct gaaaccgacg cgtaatgcgt tggggattct tggtgggatc
    53221 ccgcgccgtg aatttactcg cgacagcatc gaagagaaag tcgctgctac cacgcaagca
    53281 caatggccgg ttcatgcggt gatcaccaac tccacctatg atggcttgct ctacaacacc
    53341 gactggatca aacagacgct ggatgtcccg tcgattcact tcgattctgc ctgggtgccg
    53401 tacacccatt ttcatccgat ctaccagggt aaaagtggta tgagcggcga gcgtgttgcg
    53461 ggaaaagtga tcttcgaaac gcaatcgacc cacaaaatgc tggcggcgtt atcgcaggct
    53521 tcgctgatcc acattaaagg cgagtatgac gaagaggcct ttaacgaagc ctttatgatg
    53581 cataccacca cctcgcccag ttatcccatt gttgcttcgg ttgagacggc ggcggcgatg
    53641 ctgcgtggta atccgggcaa acggctgatt aaccgttcag tagaacgagc tctgcatttt
    53701 cgcaaagagg tccagcggct gcgggaagag tctgacggtt ggtttttcga tatctggcaa
    53761 ccgccgcagg tggatgaagc cgaatgctgg cccgttgcgc ctggcgaaca gtggcacggc
    53821 tttaacgatg cggatgccga tcatatgttt ctcgatccgg ttaaagtcac tattttgaca
    53881 ccggggatgg acgagcaggg caatatgagc gaggagggga tcccggcggc gctggtagca
    53941 aaattcctcg acgaacgtgg gatcgtagta gagaaaaccg gcccttataa cctgctgttt
    54001 ctctttagta ttggcatcga taaaaccaaa gcaatgggat tattgcgtgg gttgacggaa
    54061 ttcaaacgct cttacgatct caacctgcgg atcaaaaata tgctacccga tctctatgca
    54121 gaagatcccg atttctaccg caatatgcgt attcaggatc tggcacaagg gatccataag
    54181 ctgattcgta aacacgatct tcccggtttg atgttgcggg cattcgatac tttgccggag
    54241 atgatcatga cgccacatca ggcatggcaa cgacaaatta aaggcgaagt agaaaccatt
    54301 gcgctggaac aactggtcgg tagagtatcg gcaaatatga tcctgcctta tccaccgggc
    54361 gtaccgctgt tgatgcctgg agaaatgctg accaaagaga gccgcacagt actcgatttt
    54421 ctactgatgc tttgttccgt cgggcaacat taccccggtt ttgaaacgga tattcacggc
    54481 gcgaaacagg acgaagacgg cgtttaccgc gtacgagtcc taaaaatggc gggataactt
    54541 gccagagcgg cttccgggcg agtaacgtgc tgttaacaaa taaaggagac gttatgctgg
    54601 gtttaaaaca ggttcaccat attgcgatta ttgcgacgga ttatgcggtg agcaaagctt
    54661 tctactgcga tattcttggt ttcacgctgc aaagcgaagt ctatcgcgaa gcgcgcgact
    54721 catggaaagg ggatttggcg cttaatgggc aatatgtgat tgagcttttc tcatttccgt
    54781 tcccgccgga acgacccagc cgaccggaag cttgcggtct gcgtcatctg gcttttagcg
    54841 ttgatgacat cgatgcggca gtggcgcacc ttgaaagcca taacgtgaag tgtgaaacca
    54901 tccgtgtcga tccatacacg caaaaacgct tcaccttctt taacgatccg gacgggctgc
    54961 cgttggaact gtatgagcag taaggcttgt catcgccgca tttgcccggt aacgtgccgg
    55021 gcattgctac tgtaaaatcg caccatcatg acactcacgc tcaatagaca acttctcacc
    55081 tcacgccaga ttctggtggc ctttagcggc gggcttgact ccaccgttct gctgcatcag
    55141 ttggtgcagt ggcggacgga aaatccgggt gtcgctctgc gcgctattca tgtgcatcac
    55201 ggtttaagtg ccaatgccga tgcctgggtt acgcattgcg aaaacgtctg ccaacagtgg
    55261 caggtgccgc tggtggtcga acgcgtacaa cttgcgcaag aaggactggg cattgaggcc
    55321 caggcgcggc aggcacgtta tcaggcattt gcccgcacct tgttgcccgg tgaagtgctg
    55381 gtcaccgcgc aacatctcga cgatcaatgt gaaacctttc tgctggcgct aaaacgcggc
    55441 agtggccctg ccgggctttc ggctatggcg gaagtctcgg agtttgccgg aacgcggctt
    55501 attcgcccgt tgctcgcccg cacgcggggg gaactggtgc agtgggcgcg tcagtatgat
    55561 ttacgctgga ttgaagacga aagtaatcag gacgactcat acgatcgtaa ctttctgcgc
    55621 ctgcgcgtag tgccgttatt gcagcagcgt tggccgcatt ttgccgaagc aacggcccgc
    55681 agcgccgcac tttgtgctga acaagagagc ctgctggatg aactgctggc agatgattta
    55741 gcacactgtc aatcgccgca ggggacgctg cagattgtgc caatgctggc gatgagtgat
    55801 gcccgccgcg cggcgattat ccgccgctgg ctggcagggc agaatgcacc gatgccttcc
    55861 cgcgacgcgt tggtgaggat ctggcaggaa gtggcgctgg cgcgggaaga tgcctcaccc
    55921 tgtttacgtt tgggcgcgtt tgaaatccga cgctatcagt cgcaactgtg gtggattaaa
    55981 tccgtcaccg ggcaaagcga aaacattgtg ccgtggcaga cgtggcttca accgctggaa
    56041 ttaccggcgg ggctgggaag tgtacagctt aatgcgggag gcgatattcg ccctccgcgt
    56101 gcagacgaag cggtcagcgt gcgtttcaaa gcgccaggat tgctgcatat tgtcgggcgt
    56161 aacggcggac gtaagctaaa gaaaatctgg caagagctgg gcgtgccgcc gtggctacgt
    56221 gacaccacgc cactgctgtt ttatggcgaa acgctgattg cggcggcagg ggtatttgtg
    56281 acgcaagaag gtgtggctga aggtgagaat ggcgtaagtt ttgtctggca gaaaacgctt
    56341 agttaagtga aagccggata agacgcatca aacgtcgcat ccggcgaaag tcaatcagga
    56401 ttcgcttacc accaccgtac cgatttccgg gtggctaaag ctggtaattt tatccagacg
    56461 cagctcgcgg gtttcgccag cggcctcgac gaccaggtac tccacatttt tgcgggagac
    56521 taaatcactg gcttttgcct gcaatttttc gccatctttc agctcaagtg tcagcattaa
    56581 atgatgctgg caggcgagct caagattatc gtaatcatca caattgattg gttgatacgt
    56641 atcattcatt gacataatcg ctcaccagta agtttgccgc agcgtatgct gctttttccc
    56701 tgacagcctc agaaagggcg tcgtcggcag ccatttcatt cagcactttc aaaacgcagc
    56761 ccagcgcgtc cggaacgtat cctaagtctc cgctggcgat ttccgcgtac cgcttgcgta
    56821 ttaactcaca atatttttcc acatgccctc ctgtcagcac tctgacttaa ccgtggatgc
    56881 aagtctaagc ctacgaagat aaactctgtt tcgcaaggtg actataccac actcatttct
    56941 gcaatatcag cgccgcaact gcacgtattc cgttacaatg gcctcctgat tcgaaaggag
    57001 ttttcttatg gcgcttaaag cgacaattta taaagcgacg gttaatgtgg ccgatctcga
    57061 ccgcaaccag tttctcgatg cctctctgac gctggcgcgc catccttcag aaacccagga
    57121 gcgtatgatg ctgcgcttgc tggcgtggct gaaatatgct gatgaacgtc tgcaatttac
    57181 ccgtggtttg tgtgccgatg atgagccgga agcgtggctg cgtaacgatc acctgggcat
    57241 tgatttgtgg attgagctgg ggctgccgga tgagcggcgg attaagaaag cctgcaccca
    57301 ggccgcagaa gtggcgctgt ttacctataa tagtcgggcg gcgcaaatct ggtggcagca
    57361 aaatcagagc aaatgtgtgc agtttgccaa tctttccgtc tggtatctgg acgatgaaca
    57421 actggcgaaa gtaagcgcct ttgccgatcg taccatgacg ctgcaggcaa cgattcagga
    57481 tggcgtgatc tggttatcgg atgataagaa taatctggaa gtgaacttaa ccgcctggca
    57541 acaaccttca tgattgtgat ttcccgacat gttgctattc ccgatggtga gcttgagatc
    57601 accgccattc gtgcgcaggg cgcgggcggg cagcatgtta ataagacctc aacggctatt
    57661 catctgcgtt ttgacattcg ggcgtccagc ctgccagagt attacaaaga gcgtctgctc
    57721 gccgccagcc atcatttgat cagcagtgat ggcgtgattg tcattaaggc acaggaatac
    57781 cgcagtcagg aactgaaccg cgaagcagct ctggcccggc tggtggctat gattaaagaa
    57841 ttaacaacag aaaaaaaagc ccgacgaccc acgcggccca cccgtgcatc gaaagagcgc
    57901 aggctggcat cgaaagcaca aaaatcaagc gtgaaggcga tgcgcggcaa agtgcgcagc
    57961 ggtcgggaat aaaaagaagg aatggatggt gaaaaaagcg atagtgacag cgatggctgt
    58021 aatcagcctc tttactctga tgggatgtaa taatcgggcc gaagtcgata cgctttctcc
    58081 ggcgcaggct gccgaactga aaccgatgcc gcaaagttgg cgcggcgtgc tgccgtgtgc
    58141 cgattgcgaa ggaatcgaaa cctctctgtt cctcgaaaaa gacggaacat gggtgatgaa
    58201 tgagcgttat ctcggtgctc gtgaagaacc ttcctccttc gcttcctacg gtacatgggc
    58261 gcgaaccgct gacaagctgg tattaaccga cagcaaaggt gaaaagtcat attatcgggc
    58321 gaaaggcgat gcgctggaga tgctcgatcg tgaaggcaat ccgattgaat cgcagttcaa
    58381 ctatacgctg gaagcggcac aatccagttt acctatgacg ccgatgaccc tgcggggcat
    58441 gtatttttat atggctgatg cggcgacctt cactgattgc gcgaccggaa aacgtttcat
    58501 ggtagcgaat aacgcagagc tggagcgtag ctacctggct gcgcgcggtc acagtgaaaa
    58561 accggtgtta ctgtcagtag aaggtcactt tacgcttgag ggtaatccgg ataccggtgc
    58621 gccgactaaa gtattggcac ccgatacggc agggaaattt taccccaacc aggattgcag
    58681 tagtttgggg cagtaacccg tcttgagaca gaaacaaacg caaaacaggc cagaaggata
    58741 tatttcaaca ttttgaattt gcacgttttt tgtaggccgg ataaggcgtt tacgccgcat
    58801 ccggcaatgg tgctcaacgc ctgatgcgac gctggcgcgt cttatcatgc ctacaacccc
    58861 cctcatacct taaggcggat aaggcattta ctttatcacc gggtcaaacc aacaaagcga
    58921 cccgccttga tataaatccc aggcttcagg tgcccaacat actgtaactg cgtttctggc
    58981 ttaaacgcag agacatcacc aatacgcata tgcatcagat cggcagggct aatccagccc
    59041 gattgcgcca gtgtaagtgg atgcccggct ttggcaaagg catccgtgac aaattccgaa
    59101 caaaaccacg actttttgtc tccttcgccc acactgctta actgcgcttt cgccaggccg
    59161 ctgacgcact gttggcgaaa atcctcggag aacggattca gtgagcacat ctggcgagtc
    59221 accataaagg gaataaattc gacaatgccg cgatagttat aaccgctatc tttgatttta
    59281 ttggcaaacg cggtgatatc tgtggcttgt tgcggggtaa gatccgggac tcgtaagacg
    59341 aaaagcttat cactatgctt catcgctttt ttaagggaaa cgatctggac gccagcgcct
    59401 gtcgcttctg caacgttatt atcacccaga aagattgcaa cgtgactcac agaggaagtg
    59461 ctgaagacgc ggattccaaa tgaggttacc ccaaggcttg aggagaacag caaatcgccg
    59521 ggtttgagat caggtgccgt tatttctttt attgattgtt cggtgaaaga gctttgatgc
    59581 tggaatttga cagcccatgt ttttgcctcg gcatctactg ctgtggctga tgggtctggc
    59641 tggctgatat caacggtaca agccgaaagt aaaagaaagc tggggagaaa caggcggcag
    59701 tacgcctttg gtttatccat tttatacaat ccatgtaaaa aaagggccct gaaattcagg
    59761 accctttctg gcatcagcct ttaatctgtt tcaccagata ttcgacgatg tcaccagtct
    59821 taattaactg tttctcgccg ttgcgacgat atttatattc gatatcgtcg ttgtcgaggt
    59881 tacggtcgcc cagcacaata gtgtgcggaa taccgatcag ttccatatca gcaaacatca
    59941 cgcccggacg ctctttgcgg tcatccagca gcacttcgat accttgtgca cgcagttcgc
    60001 tgtacagttt ctcagcaagc tcttgtacgc ggaaggattt gtgcatgttc atcggcagaa
    60061 tcgccacctg gaacggcgcg atagcgtcag gccatacgat gcctcgttcg tcgtagttct
    60121 gctcaatcgc cgcagctacc acacgcgtta ccccgatacc gtagcaaccc atcgtcagga
    60181 tttggttacg gccatcttca ccctgtacgg aggctttcag tgcttcggag tacttggtac
    60241 ccagctggaa gatgtgacca acttcgatac cacgtttgat cagcagcgta ccctggccat
    60301 ccgggcttgg atcgccagcc accacgttac ggatatctgc aacttccggg gtagcgacat
    60361 cgcgatccca gttgatgccg aagtagtgtt taccatcgat gttagcacca gcagcgaaat
    60421 cactcatcgc cgcaacggta cggtcaatca ccaccggaat cggcatgttt accggaccca
    60481 gtgaacccgg accggcttta accacggcac gaatttcttc ttcggtcgcg aaagtcagcg
    60541 ggcttgcaac ctgcggcagt ttttctgctt taacttcgtt cagctcgtga tcaccgcgca
    60601 ccagcagcgc aaccagcggg aagctgctgc cttcaaccgc tttaaccagc agagtcttaa
    60661 ccgttttctc aatcggcaga ttgaactgtt caaccagttc cgcgatggtt ttcgcgttcg
    60721 gcgtatcaac cagcgtcatt tcctgggtag cagcagcgcg cggttctttc ggcgcgatag
    60781 cttctgccag ttcaatgttc gctgcatagt cagaggtgtc ggagaagacc acatcgtctt
    60841 caccgctctg cgccagcacc tggaattcgt gagaggcgct gccgccgata gaaccggtgt
    60901 cggcttgtac ggcgcggaaa tccagcccca tgcggctgaa gattttgctg taggccgcat
    60961 acattgcatc gtaggtttcc tgcagggatt cctgagaagt atggaaagag taagcatctt
    61021 tcatcaggaa ttcgcgggaa cgcatgacgc cgaaacgcgg acgcacttcg tcgcggaact
    61081 tggtctggat ctgatagaag ttcagcggca gctgtttgta agagctaagc tcgttacgaa
    61141 tcaggtcagt gataacttct tcatgagttg ggccgagtac gaacggacgc tcgccacggt
    61201 caacaaaacg cagcagttcc ggaccgtact gttcccaacg accactctct tgccacaaat
    61261 cggctggctg aaccaccggc atcgacacct cgatcgcacc ggcgttgttc atctcttcac
    61321 gcacgatgtt ttcgactttt ttcagaacgc gcacgccggt cggcagccag gtatataacc
    61381 cggaggccag cttgcggatc atcccggcgc gcagcatcag ctgatggctg atcacctcgg
    61441 cgtcggcagg tgtctccttg agagtggaga gcaggtattg gctagtacgc atgttgttac
    61501 ggttccagtt ggaaggtaga acaggctcaa ggcgagcctg ggacaaaaaa aagtgattta
    61561 gtttaccagt gcaaaagaaa tgtcaaaaga gaagggcgtg aatttaacgc ggttccagcg
    61621 caaagacttc aaaacctgcg tcggtgacgc gccagcgaac gttaaaatca tgtagccaga
    61681 cggcataggt tttgcccgtt tcctcacctt tacgataggc cgggcgcggg tcctgcgcca
    61741 gtacttcgcg gataaacagc gttaactgcg gataacgctt ctccagcgtc aaaagctgct
    61801 tttcgacctc tgcggtaaaa ctcaccgcca tctctgcagc tggcgcactt tgcgcatagc
    61861 tggcactggc atcgggaagc gattcggcaa aggggagata cggtttgata tccactaccg
    61921 gcgtaccatc gaccagatcc agactgccga gcttcagaat cacgctgtct ttatggcaaa
    61981 caacctcttt cagctctacc agcgacatgc caattgggtt agggcggaaa gtagagcgtg
    62041 ttgcgaaaac ccccattctg gcgttaccgc cgaggcgcgg tggacgcaca gtcggacgcc
    62101 agccgccttc catcgtttga tgaaagacga aaaggatcca taaatggctg aacgcttcca
    62161 ggccgcgaac ggcgtcggcc tggttgtagg gagcaatgag atgcagttcg ccgttggcgc
    62221 tttttaccag acctggctgg cgcggaacgg cgaacttttc tttatagggc gagcgaataa
    62281 cgcctatttg ctcgaactgg aaactgctca tttcgccgta atgttaagcg cagaaccgat
    62341 acatacagcc tgacgatagc agcctggcgt accgctggtg acttcgcagc tatgcagtaa
    62401 tacagcattg gctttcattt tagaggcgtt gatttgcatc cgcttacgtg cggttggaat
    62461 gctcggcgga gagtcctgat tagaggcctg gcaagagtcg ccactgactt caccgagatc
    62521 gcggaacggt ttgccgacta attcttctgc attggtataa attcggaccg gcgtggcgcg
    62581 cggcgctttc ggttttgcag gctccgcttt cggctggggt gcagtgcttt gaacgggttc
    62641 gacaggggat ctgcttaaca tggaacagcc gcttagcatg agtgctacta aacagatcgg
    62701 taaagcacgc atagtatttc ctcaatgtat gatcaaaacg tcaatattga atcaggagct
    62761 tgtaaaaatg acaagacggg caagcgcccg tcctgaatga tattacaaat tgtggaaaca
    62821 gcctaaaaat taccagcctt taacagctcc gccgttaaac actttgtttg ctgcttcgta
    62881 aacttcgtca gactgataag cctggacgaa tttcttcacg ttctcggcgt ctttgttatc
    62941 ttcacgcgtc acgatcaggt ttacgtacgg ggactcttta tcttcaacaa agataccgtc
    63001 tttcgccgga gtcaggccaa tctggctggc ataggtggta ttgataactg ccagagcgat
    63061 ttgcgcgtcg tccagagaac gcggcagttg cggtgcttcc agttcaacaa ttttcagatt
    63121 tttggggttc tcaacaacat caagaacggt cggcagcagg ccaacgccat ctttcagttt
    63181 gatcaagccc actttttgca gcagcagcag tgaacgacca aggttagttg ggtcgtttgg
    63241 cacggcaacc tgcgaaccat cctgcagttc atccagtgat ttgattttct tggagtaacc
    63301 agcaatcgga taaacaaaag tgttgcctac tgcgaccagt ttgtagccac gatctttcag
    63361 ttgctgatca aggtacggtt tatgctggaa ggcgttggcg tcgatatcgc ctttgctcaa
    63421 tgcttcgttt ggcagaacat agtcgttgaa ggttaccagc tcaacgtcca ggccatattt
    63481 gtctttcgca actttctgcg cgacttctgc aacctgctgt tcggcaccaa caatcacgcc
    63541 gactttaatg tggtttggat ctttttcatc ctgaccgcag cctaccagtg ccagtgatcc
    63601 gatcagggct cccactgccg caaaggtttt gaatttgaac gccatacctt attccttctt
    63661 caattattta tgttgtgttg aacgttactt gcgagtgaca gcccggacga tgcggtcgcc
    63721 tgcgaactga attaaataaa ccagaatgac cagcaatacc agtaccgtat tcatcaccgt
    63781 cgcgttatag ccgatgtagc catactgata gccaatctga cctaaaccac cggcaccgac
    63841 tgcaccaccc atcgcggaat aaccgaccag ggtaatcagg gtgatagttg ccgcattcac
    63901 cagacccggc agcgcttccg gtaacagcac cttacggacg atctgcatcg gcgtggcacc
    63961 cattgcgcgg gaagcttcaa ttaacccggt tgggatctcc agcagagcgt tctcgaccat
    64021 acgggcaata aacggtgctg caccaacggt taacggaaca atcgctgcct gcaaaccaat
    64081 cgatgtaccg acaataacgc gggtaaacgg aatcatccat acaagcaaga taatgaacgg
    64141 gatggaacgg aaaatgttca caatcgcaga aacggtacga tacagcttcg cgttagcaat
    64201 aatttgcccc ggacgcgtga cataaagcag aacgccaacc ggcagaccaa tcacaaagcc
    64261 aaaaaaaccg gatacgaagg tcattgccag cgtttcccat acgccacgaa ccagcagcca
    64321 catcatcggc tcagacataa cccagtacct ctacttttac atggtgttcc tgcagccagg
    64381 caatggcggc ttgcgtatct tgttgtgtgc cgtgcatttc agtcagcatg atgccgaact
    64441 taacgccacc ggcgtaatcc atctgcgcgc taataatgtt gttgttgacg ttgaaacgac
    64501 gcgcggtttc agaaagcagt ggggcatcga ccgattgacc ggtaaactcc agacgcagca
    64561 tcggcacgca gtcagtaaat ggctccgctt gcagacgttc ctggtaatct tccgggatat
    64621 ccagatgcag ggtcgactga ataaacttct gcgccagcgg cgttttcgga tgcgagaaca
    64681 cttcacttac cgtgtcctgc tcgatcagtt ctccattgct gatgaccgcc acgcaatcac
    64741 aaatgcgctt cacaacgtcc atttcgtggg tgatcaacag aatcgtcaac cccagacggc
    64801 ggttgatgtc tttcagcagt tcgagaatag aacgtgtcgt tgccgggtcc agcgcgctgg
    64861 tggcttcatc acacagcaat actttgggat tgctggctaa cgcacgggca attgccacac
    64921 gttgtttctg cccaccggaa agattcgacg ggtagctatc atgcttatcg ccaagaccaa
    64981 ccaatgacag caattccgtc acgcgacgtt tgacctcgtc tttcggtgtg ttgtccagct
    65041 ccagcggcag agccacgttg ccaaaaacag tacgcgaaga gagcaggtta aaatgctgga
    65101 aaatcatacc aatctggcgg cgagctttgg tcaactcgga ttctgacagc gtggtcagtt
    65161 cctggccatc gaccagcacg ctaccctcgg ttgggcgctc cagcaggttt acacaacgta
    65221 taagcgtact cttacccgcg cctgaggcac cgataacgcc ataaatttgt ccagctggca
    65281 catgcaggct gacgttgttc aacgcctgga tggtgcgggt gccctggtgg aacactttgg
    65341 tgatattcga aagttttatc attgattatt tattatcgtc attaagttag tcgtggcatc
    65401 tcgaatgcct gaaacgggca acgccgtcaa tgaaatggat gttaaggcat ccagacgtct
    65461 aaatcaatca ggtttatgcg aagagcactt tcttgcaggt cgaaacatgc gatactagcg
    65521 tcacatgcct tattaaggag ctataaaagg tggcgaagag cgtacccgca atttttcttg
    65581 accgtgatgg caccattaat gtcgatcacg gctatgtcca tgagatcgac aactttgaat
    65641 ttatcgacgg tgttattgac gccatgcgcg agctaaaaaa aatgggcttt gcgctggtgg
    65701 tagtaaccaa ccagtctggc attgctcgcg gtaaatttac cgaagcacag tttgaaacgc
    65761 tgaccgagtg gatggactgg tcgctggcgg accgagatgt cgatctggat ggtatctatt
    65821 attgcccgca tcatccgcag ggtagtgttg aagagtttcg ccaggtctgc gattgccgca
    65881 aaccacatcc ggggatgctt ttgtcagcac gcgattattt gcatattgat atggccgctt
    65941 cttatatggt gggcgataaa ttagaagata tgcaggcagc ggttgcggcg aacgtgggaa
    66001 caaaagtgct ggtgcgtacg ggtaaaccta ttacgcctga agcagaaaac gcggcggatt
    66061 gggtgttaaa tagcctggca gacctgccgc aagcgataaa aaagcagcaa aaaccggcac
    66121 aatgattaaa agatgagcgg ttgaaataaa aatgcatttt tccgcttgtc ttcctgagcc
    66181 gactccctat aatgcgcctc catcgacacg gcggatgtga atcacttcac acaaacagcc
    66241 ggttcg
//
LOCUS       DACAOP010000016        65603 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.016, whole genome shotgun sequence.
ACCESSION   DACAOP010000016 DACAOP010000000
VERSION     DACAOP010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 65603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65603
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.016"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            83..496
                     /locus_tag="IT892_001146"
     CDS             83..496
                     /locus_tag="IT892_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAP3134385.1"
                     /translation="MKETDIAGILTSTHTIALVGASDKPDRPSYRVMKYLLDQGYHVI
                     PVSPKVAGKTLLGQKGYGTLADVPEKVDMVDVFRNSEAAWGVAQEAIAIGAKTLWMQL
                     GVINEQAAVLARDAGLNVVMDRCPAIEIPRLGLAK"
     gene            complement(541..858)
                     /gene="hspQ"
                     /locus_tag="IT892_001147"
     CDS             complement(541..858)
                     /gene="hspQ"
                     /locus_tag="IT892_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HspQ"
                     /protein_id="HAP3134386.1"
                     /translation="MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVND
                     ELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPR
                     LRN"
     gene            complement(916..2106)
                     /gene="rlmI"
                     /locus_tag="IT892_001148"
     CDS             complement(916..2106)
                     /gene="rlmI"
                     /locus_tag="IT892_001148"
                     /EC_number="2.1.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415487.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytosine(1962)-C(5))-methyltransferase
                     RlmI"
                     /protein_id="HAP3134387.1"
                     /translation="MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVD
                     HQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFSRRLQQAQKWRDWLAQKDGLDSY
                     RLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECSIYDRSDVA
                     VRKKEGMELTQGPVTGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRY
                     VENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFV
                     RDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEGGI
                     LLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFA
                     CRVM"
     gene            2201..2479
                     /gene="yccX"
                     /locus_tag="IT892_001149"
     CDS             2201..2479
                     /gene="yccX"
                     /locus_tag="IT892_001149"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAP3134388.1"
                     /translation="MSKVCIIAWVYGRVQGVGFRYTTQYEAKRLGLTGYAKNLDDGSV
                     EVVACGEEGQVEKLMQWLKSGGPRSARVERVLSEPHHPSGELTDFRIR"
     gene            complement(2476..2805)
                     /gene="tusE"
                     /locus_tag="IT892_001150"
     CDS             complement(2476..2805)
                     /gene="tusE"
                     /locus_tag="IT892_001150"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusE"
                     /protein_id="HAP3134389.1"
                     /translation="MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGISLSPEHW
                     EVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGL
                     PKPVKCI"
     gene            complement(2896..3555)
                     /gene="yccA"
                     /locus_tag="IT892_001151"
     CDS             complement(2896..3555)
                     /gene="yccA"
                     /locus_tag="IT892_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease modulator YccA"
                     /protein_id="HAP3134390.1"
                     /translation="MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTV
                     LMLPSPGLILTLVGMYGLMFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYLSAGM
                     GDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
                     HLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASR
                     D"
     gene            complement(3762..3849)
                     /locus_tag="IT892_001152"
     tRNA            complement(3762..3849)
                     /locus_tag="IT892_001152"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3813..3815),aa:Ser,seq:tga)
     gene            4276..5394
                     /gene="hyaA"
                     /locus_tag="IT892_001153"
     CDS             4276..5394
                     /gene="hyaA"
                     /locus_tag="IT892_001153"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 small subunit"
                     /protein_id="HAP3134391.1"
                     /translation="MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAW
                     ALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAE
                     EVFEDIITQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTC
                     ASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVD
                     RMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACS
                     STRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGV
                     VAAAVGVHAVASAVDQRRRHNQQPTETEHQPGNEDKQA"
     gene            5391..7184
                     /gene="hyaB"
                     /locus_tag="IT892_001154"
     CDS             5391..7184
                     /gene="hyaB"
                     /locus_tag="IT892_001154"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase large subunit"
                     /protein_id="HAP3134392.1"
                     /translation="MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVIT
                     NAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDN
                     ANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSP
                     GYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVK
                     IHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQSIITRTADFINNVMI
                     PDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNV
                     LPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQ
                     ERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLG
                     RILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAP
                     RGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEI
                     LRTLHSFDPCLACSTHVLGDDGSELISVQVR"
     gene            7203..7910
                     /gene="hyaC"
                     /locus_tag="IT892_001155"
     CDS             7203..7910
                     /gene="hyaC"
                     /locus_tag="IT892_001155"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase b-type cytochrome subunit"
                     /protein_id="HAP3134393.1"
                     /translation="MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLP
                     SVSGEATYLFYMGYIRLIHFSAGMVFTVVLLMRIYWAFVGNRYSRELFIVPVWRKSWW
                     QGVWYEIRWYLFLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIF
                     APFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMV
                     NGYRSHKFGKISNKERS"
     gene            7907..8494
                     /locus_tag="IT892_001156"
     CDS             7907..8494
                     /locus_tag="IT892_001156"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 maturation protease"
                     /protein_id="HAP3134394.1"
                     /translation="MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEYVEIVDG
                     GTQGLNLLGYVESASHLLILDAIDYGLEPGTLRTYAGERIPAYLSAKKMSLHQNSFSE
                     VLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVP
                     QPANESRCLNYDCLSMENYEGVRLRQYRMTQEEQG"
     gene            8491..8889
                     /gene="hyaE"
                     /locus_tag="IT892_001157"
     CDS             8491..8889
                     /gene="hyaE"
                     /locus_tag="IT892_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-1 operon protein HyaE"
                     /protein_id="HAP3134395.1"
                     /translation="MSNDTPFDALWQRMLARGWTPVSESRLDDWLTQAPDGVVLLSSD
                     PKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQSEAIGDRFGVFRFPATLVFTGGN
                     YRGVLNGIHPWAELINLMRGLVEPQQERVS"
     gene            8886..9743
                     /locus_tag="IT892_001158"
     CDS             8886..9743
                     /locus_tag="IT892_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein"
                     /protein_id="HAP3134396.1"
                     /translation="MSETFFHLLGPGTQPNDDSFSMNPLPITCQVNDEPSMAALEQCA
                     HSPQVIALLNELQHQLSERQPPLGEVLAVDLLNLNADDRHFINTLLGEGEVSVRIQQA
                     DDSESEIQEAIFCGLWRVRRRRGEKLLEDKLEAGCAPLALWQAATQNLLPTDSLLPPP
                     IDGLMNGLPLAHELLAHVRNPDAQPHSINLTQLPISEADRLFLSRLCGPGNIQIRTIG
                     YGESYINATGLRHVWHLRCTDTLKGPLLESYEICPIPEVVLAAPEDLVDSAQRLSEVC
                     QWLAEAAPT"
     gene            9877..11421
                     /gene="appC"
                     /locus_tag="IT892_001159"
     CDS             9877..11421
                     /gene="appC"
                     /locus_tag="IT892_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit 1"
                     /protein_id="HAP3134397.1"
                     /translation="MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAIMETIYVVTG
                     KTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTNWSFYSNYVGDIFGAPLAMEALM
                     AFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNLSALWILNANGWMQYPTGAHFD
                     IDTLRMEMTSFSELVFNPVSQVKFVHTVMAGYVTGAMFIMAISAWYLLRGRERDVALR
                     SFAIGSVFGTLAIIGTLQLGDSSAYEVAQVQPVKLAAMEGEWQTEPAPAPFHVVAWPE
                     QDQERNAFALKIPALLGILATHSLDKPVPGLKNLMAETYPRLQRGRMAWLLMQEISQG
                     NREPHVLQAFRGLEGDLGYGMLLSRYAPDMNHVTAAQYQAAMRGAIPQVAPVFWSFRI
                     MVGCGSLLLLVMLIALVQTLRGKIDQHRWVLKMALWSLPLPWIAIEAGWFMTEFGRQP
                     WAIQDILPTYSAHSALTTGQLAFSLIMIVGLYTLFLIAEVYLMQKYARLGPSAMQSEQ
                     PTQQQG"
     gene            11433..12569
                     /gene="appB"
                     /locus_tag="IT892_001160"
     CDS             11433..12569
                     /gene="appB"
                     /locus_tag="IT892_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HAP3134398.1"
                     /translation="MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARNDD
                     ERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPL
                     AFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
                     FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLA
                     GYWLWVGIDGFVLLAQDANGPSNPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPL
                     LTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQL
                     TLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY"
     gene            12582..12674
                     /gene="cbdX"
                     /locus_tag="IT892_001161"
     CDS             12582..12674
                     /gene="cbdX"
                     /locus_tag="IT892_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit CbdX"
                     /protein_id="HAP3134399.1"
                     /translation="MWYLLWFVGILLMCSLSTLVLVWLDPRLKS"
     gene            12754..14052
                     /locus_tag="IT892_001162"
     CDS             12754..14052
                     /locus_tag="IT892_001162"
                     /EC_number="3.1.3.2"
                     /EC_number="3.1.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AppA family phytase/histidine-type acid
                     phosphatase"
                     /protein_id="HAP3134400.1"
                     /translation="MKAILIPFLSLLIPLTPQSAFAQSEPELKLESVVIVSRHGVRAP
                     TKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQS
                     GQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNA
                     NVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKREKQDESCSLTQALPS
                     ELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQF
                     YLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHDTNLANLGG
                     ALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNT
                     PPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL"
     gene            complement(14167..16347)
                     /gene="etk"
                     /locus_tag="IT892_001163"
     CDS             complement(14167..16347)
                     /gene="etk"
                     /locus_tag="IT892_001163"
                     /EC_number="2.7.10.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HAP3134401.1"
                     /translation="MTTKNMNTPPGSTQENEIDLLRLVGELWDHRKFIISVTALFTLI
                     AVAYSLLSTPIYQADTLVQVEQKQGNAILSGLSDMIPNSSPESAPEIQLLQSRMILGK
                     TIAELNLRDIVEQKYFPIVGRGWARLTKEKPGELAISWMHIPQLNGQDQQLTLTVGEN
                     GHYTLEGEEFTVNGMVGQRLEKDGVALTIADIKAKPGTQFVLSQRTELEAINALQETF
                     TVSERSKESGMLELTMTGDDPQLITRILNSIANNYLQQNIARQAAQDSQSLEFLQRQL
                     PEVRSELDQAEEKLNVYRQQRDSVDLNLEAKAVLEQIVNVDNQLNELTFREAEISQLY
                     KKDHPTYRALLEKRQTLEQERKRLNKRVSAMPSTQQEVLRLSRDVEAGRAVYLQLLNR
                     QQELSISKSSAIGNVRIIDPAVTQPQPVKPKKALNVVLGFILGLFISVGAVLARAMLR
                     RGVEAPEQLEEHGISVYATIPMSEWLDKRTRLRKKNLFSNQQRHRTKNIPFLAVDNPA
                     DSAVEAVRALRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIAQSDQKVLFI
                     DADLRRGYSHNLFTVSNEHGLSEYLAGKDELNKVIQHFGKGGFDVITRGQVPPNPSEL
                     LMRDRMRQLLEWANDHYDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFGLNTAKEVS
                     LSMQRLEQAGVNIKGAILNGVIKRASTAYSYGYNYYGYSYSEKE"
     gene            complement(16367..16813)
                     /gene="etp"
                     /locus_tag="IT892_001164"
                     /gene_synonym="yccY"
     CDS             complement(16367..16813)
                     /gene="etp"
                     /locus_tag="IT892_001164"
                     /gene_synonym="yccY"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine-phosphatase Etp"
                     /protein_id="HAP3134402.1"
                     /translation="MAQLKFNSILVVCTGNICRSPIGERLLRKRLPGVKVKSAGVHGL
                     VKHPADATAADVAANHGVSLEGHAGRKLTAEMARNYDLILAMESEHIAQVTAIAPEVR
                     GKTMLFGQWLEQKEIPDPYRKSQDAFEHVYGMLERASQEWAKRLSR"
     gene            complement(16801..17940)
                     /locus_tag="IT892_001165"
     CDS             complement(16801..17940)
                     /locus_tag="IT892_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HAP3134403.1"
                     /translation="MKKNIFKFSVLTLAVLSLTACTLVPGQNLSTSNKDVIELPDNQY
                     DLDKMVNIYPVTPGLIDQLRAKPIMSQANPELEQQIANYEYRIGIGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNADGAIFYPYIGRLKVAGKTLTQVRNEITARLDSVIESPQ
                     VDVSVAAFRSQKAYVTGEVSKSGQQPITNIPLTIMDAINAAGGLTADADWRNVVLTQN
                     GVKTKVNLYALMQRGDLRQNKLLHPGDILFIPRNDDLKVFVMGEVGKQSTLKMDRSGM
                     TLAEALGNAEGMNQDVADATGIFVIRATQNKQNGKIANIYQLNAKDASAMILGTEFQL
                     EPYDIVYVTTAPLARWNRVISLLVPTISGVHDLTETSRWIQTWPN"
     gene            complement(17986..20082)
                     /locus_tag="IT892_001166"
     CDS             complement(17986..20082)
                     /locus_tag="IT892_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HAP3134404.1"
                     /translation="MKKNSYLLSCLAIAVSSACHAEVLTYPDPLGSSQSDFGGTGLLQ
                     MPNARIAPEGEFSVNYRDNDQYRFYSTSVALFPWLEGTIRYTDVRTRKYSQWEDFSGD
                     QSYKDKSFDFKLRLWEEGYWLPQVAFGKRDIAGTGLFDGEYLVASKQAGPFDFTLGMA
                     WGYAGNAGNITNPFCRVSDKYCHRAESHDAGDISFSDIFRGPASIFGGIEYQTPWNPL
                     RLKLEYDGNNYQNDFAGKLPQASHFNVGAVYRAASWADLNLSYERGNTLMFGFTLRTN
                     FNDLRPALRDTPKPAYQPAPESEGLQYTTVANQLTALKYNAGFDAPEIQLRDKTLYMS
                     GQQYKYRDSREAVDRANRILVNNLPQGVEKISVTQKREHMAMVTTETDVASLRKQLAG
                     TAPGQSEPLQQQRVEAEDLSAFGRGYRIREDRFSYSFNPTLSQSLGGPEDFYMFQLGL
                     MSSARYWFTDHLLLDGGIFTNIYNNYDKFKSSLLPADSTLPRVRTHIRDYVRNDVYLN
                     NLQANYFADLGNGFYGQVYGGYLETMYAGVGSELLYRPLDACWALGVDVNYVKQRDWD
                     NMMRFTDYSTPTGFVTAYWNPPTLNGVLMKLSVGQYLAKDKGATIDVAKRFDSGVAVG
                     VWAAISNVSKDDYGEGGFSKGFYISIPFDLMTIGPNRNRAVVSWTPLTRDGGQMLSRK
                     YQLYPMTAEREVPVGQ"
     gene            complement(20082..20828)
                     /locus_tag="IT892_001167"
     CDS             complement(20082..20828)
                     /locus_tag="IT892_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HAP3134405.1"
                     /translation="MNKLQSYFIASVLYVMTPHAFAQGTVTIYLPGEQQTLSVGPVEN
                     VVQLVTQPQLRDRLWWPGALLTDSAAKAKALKDYQHVMAQLASWEAEADDDVAATIKS
                     VRQQLLNLNITGRLPVKLDPDFVRVDENSNPPLVGDYTLYTVQRPVTITLLGAVSGAG
                     QLPWQAGRSVTDYLQDHPRLAGADKNNVMVITPEGETVVAPVALWNKRHVEPPPGSQL
                     WLGFSAHVLPEKYADLNDQIVSVLTQRVPD"
     gene            complement(20825..21469)
                     /gene="gfcB"
                     /locus_tag="IT892_001168"
     CDS             complement(20825..21469)
                     /gene="gfcB"
                     /locus_tag="IT892_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein GfcB"
                     /protein_id="HAP3134406.1"
                     /translation="MRPLILSIFALFLAGCTHSQQSMVDTFRASLFDNQDITVADQQI
                     QALPYSTMYLRLNEGQRIFVVLGYIEQEQSKWLSQDNAMLVTHNGRLLKTVKLNNNLL
                     EVTNSGQDPLRNALAIKDGSRWTRDILWSEDNHFRSATLSSTFSFAGLETLNIAGRNV
                     LCNVWQEEVTSTRPEKQWQNTFWVDSATGQVRQSRQMLGAGVIPVEMTFLKPAP"
     gene            complement(21576..21881)
                     /locus_tag="IT892_001169"
     CDS             complement(21576..21881)
                     /locus_tag="IT892_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine-rich inner membrane protein GfcA"
                     /protein_id="HAP3134407.1"
                     /translation="MKHKLSAILMAFMLTTPAAFAAPEATNGTEATTGTTGTTTTTTG
                     ATTTATTTGGVAAGAVGTATVVGVATAVGVATLAVVAANDSGDGGSHNTSTTTSTTR"
     gene            complement(22323..22535)
                     /gene="cspH"
                     /locus_tag="IT892_001170"
     CDS             complement(22323..22535)
                     /gene="cspH"
                     /locus_tag="IT892_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspH"
                     /protein_id="HAP3134408.1"
                     /translation="MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEV
                     LIPGLRVEFCRVNGLRGPTAANVYLS"
     gene            22821..23033
                     /gene="cspG"
                     /locus_tag="IT892_001171"
     CDS             22821..23033
                     /gene="cspG"
                     /locus_tag="IT892_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspG"
                     /protein_id="HAP3134409.1"
                     /translation="MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRT
                     LNENQKVEFSIEQGQRGPAAANVVTL"
     gene            23044..23232
                     /locus_tag="IT892_001172"
     CDS             23044..23232
                     /locus_tag="IT892_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP3134410.1"
                     /translation="MTQHLHFRCPCCHGSQYRTSAFDVTERNPLGAKCIFCKSTMITF
                     DNVALQIRTDHAPLDFTK"
     gene            23207..23437
                     /gene="ymcE"
                     /locus_tag="IT892_001173"
     CDS             23207..23437
                     /gene="ymcE"
                     /locus_tag="IT892_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmcE"
                     /protein_id="HAP3134411.1"
                     /translation="MRRWISQNNIRLPRGAFFISALFFFNAVCIVSDNLLIIESFGEM
                     AYNISYLTRVPGTNTLLACCCLLRPEEVNSEY"
     gene            23427..23600
                     /locus_tag="IT892_001174"
     CDS             23427..23600
                     /locus_tag="IT892_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HAP3134412.1"
                     /translation="MNIEELKKQAETEIADFIAQKIAELNKNTGKEVSEIRFTAREKM
                     TGLESYDVKIKIM"
     gene            complement(23649..24722)
                     /locus_tag="IT892_001175"
     CDS             complement(23649..24722)
                     /locus_tag="IT892_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HAP3134413.1"
                     /translation="MAENKRTRWQRRPGTTGGKLPWNDWRNATTWRKATQLLLLAMNI
                     YIAITFWYWVRYYETASSTTFVARPGGIEGWLPIAGLMNLKYSLVTGQLPSVHAAAML
                     LLVAFIVISLLLKKAFCSWLCPVGTLSELIGDLGNKLFGRQCVLPRWLDIPLRGVKYL
                     LLSFFIYIALLMPAQAIHYFMLSPYSVVMDVKMLDFFRHMGTATLISVTVLLIASLFI
                     RHAWCRYLCPYGALMGVVSLLSPFKIRRNAESCIDCGKCAKNCPSRIPVDKLIQVRTV
                     ECTGCMTCVESCPVASTLTFSLQKPAANKKAFALSGWLMTLLVLGIMFAVIGYAMYAG
                     VWQSPVPEELYRRLIPQAPMIGH"
     gene            complement(24794..27538)
                     /gene="torS"
                     /locus_tag="IT892_001176"
     CDS             complement(24794..27538)
                     /gene="torS"
                     /locus_tag="IT892_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415513.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system sensor histidine
                     kinase/response regulator TorS"
                     /protein_id="HAP3134414.1"
                     /translation="MNLTLTRRLWMGFALMALLTLTSTLVGWYNLRFISQVEKDNTQA
                     LIPTMNMARQLSEASAWELFAAQNLTSADNEKMWQAQGRMLTAQSLKINALLQALREQ
                     GFDTTAIEQQEQEISRSLRQQGELVGQRLQLRQQQQQLSQQIVAAADEIARLAQGQAN
                     NATTSAGATQAGIYDLIEQDQRQAAESALDRLIDIDLEYVNQMNELRLSALRVQQMVM
                     NLGLEQIQKNAPTLEKQLNNAVKILQRRQIRIEDPGVRAQVATTLTTVSQYSDLLALY
                     QQDSEISNHLQTLAQNNIAQFAQFSSEVSQLVDTIELRNQHGLAHLEKASARGQYSLL
                     LLGMVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDIDSPFPETAGVRELDTIG
                     RLMDAFRSNVHALNRHREQLAAQVKARTAELQELVIEHRQARAEAEKASQAKSAFLAA
                     MSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAG
                     GKNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIRLATAIADDMPCALMGDSRRIRQVI
                     TNLLSNALRFTDEGYIILRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG
                     GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVATAPVPKTVNQAVRLDGL
                     RLLLIEDNPLTQRITIEMLKTSGAQIVAVGNAAQALETLQNSEPFAAALVDFDLPDID
                     GITLARQLAQQYPSLVLIGFSAHVIDETLRQRTSSLFRGIIPKPVPREVLGQLLAHYL
                     QLQVNNDQSLDVSQLNEDAQLMGTEKIHEWLVLFTQHALPLLDEIDIARASQDSEKIK
                     RAAHQLKSSCSSLGMHIASQLCAQLEQQPLSAPLPHEEITRSVAALEAWLHKKDLNAI
                     "
     gene            27621..28649
                     /gene="torT"
                     /locus_tag="IT892_001177"
     CDS             27621..28649
                     /gene="torT"
                     /locus_tag="IT892_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HAP3134415.1"
                     /translation="MRVLLFLLLSLFMLPAFSADNLLRWHDAQHFTVQASTPLKAKRA
                     WKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWG
                     AEAILLGSSTTSFPDLQKQVASLPVIELVNAIDAPQVKSRVGVPWFQMGYQPGRYLVQ
                     WAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQE
                     MLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASD
                     QMVWQGELAVEQAIRQLQGQSVSDNVSPPILVLTPKNADREHIRRSLSPGGFRPVYFY
                     QHTSAAKK"
     gene            complement(28622..29314)
                     /gene="torR"
                     /locus_tag="IT892_001178"
     CDS             complement(28622..29314)
                     /gene="torR"
                     /locus_tag="IT892_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TorR"
                     /protein_id="HAP3134416.1"
                     /translation="MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQN
                     QSVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTK
                     PLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTR
                     AEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQ
                     HGEGYFLAADVC"
     gene            29444..30616
                     /gene="torC"
                     /locus_tag="IT892_001179"
     CDS             29444..30616
                     /gene="torC"
                     /locus_tag="IT892_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HAP3134417.1"
                     /translation="MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTST
                     TEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQ
                     TFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
                     KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAK
                     GDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGD
                     VQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHG
                     APEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK"
     gene            30616..33162
                     /gene="torA"
                     /locus_tag="IT892_001180"
     CDS             30616..33162
                     /gene="torA"
                     /locus_tag="IT892_001180"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HAP3134418.1"
                     /translation="MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAAT
                     DAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRY
                     PMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
                     QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLV
                     LQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTH
                     EYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEK
                     DGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLA
                     AMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIP
                     IARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGLRKLETVI
                     AIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDI
                     FRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFD
                     HPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGG
                     PGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDV
                     VRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIG
                     TSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS"
     gene            33159..33758
                     /gene="torD"
                     /locus_tag="IT892_001181"
     CDS             33159..33758
                     /gene="torD"
                     /locus_tag="IT892_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HAP3134419.1"
                     /translation="MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLL
                     KSEPPLTAAVNELENRIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQ
                     EIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTA
                     LWQWLPEFVARCRQYDSFGFYAALSQLLLVLVECDHQNR"
     gene            complement(33910..34215)
                     /gene="cbpM"
                     /locus_tag="IT892_001182"
     CDS             complement(33910..34215)
                     /gene="cbpM"
                     /locus_tag="IT892_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HAP3134420.1"
                     /translation="MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWV
                     FDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP"
     gene            complement(34215..35135)
                     /gene="cbpA"
                     /locus_tag="IT892_001183"
     CDS             complement(34215..35135)
                     /gene="cbpA"
                     /locus_tag="IT892_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curved DNA-binding protein"
                     /protein_id="HAP3134421.1"
                     /translation="MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEA
                     RFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIF
                     GQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
                     NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVS
                     PWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMP
                     PKPDENTAALWQQLADAQSSFDPRKDWGKA"
     gene            35396..36652
                     /locus_tag="IT892_001184"
     CDS             35396..36652
                     /locus_tag="IT892_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccE family protein"
                     /protein_id="HAP3134422.1"
                     /translation="MGSNIHGISCTANNYLKQAWNDIKNEYEKNQTYSITLFENTLVC
                     FMRLYNELRRKVNEEDTPCLECESLEKEFEEMQNDNDLSLFMRTLRTNDTQIYSGVSG
                     GITYTIQYVRDIDIVRVSLPGRASESITDFKGYYWYNFMEYIENINACDDVFSEYCFD
                     DENISVQPERINTPGISDLDSDIDLSGISFIQRETNQALGLKYAPVDGDGYCLLRAIL
                     VLKQHDYSWALVSYKMQKEVYNEFIKMVDKKTIEALVDTAFYNLREDVKTLFGVDLQS
                     DNQIQGQSSLMSWSFLFFKKQFIDSCLNNEKCILHLPEFIFNDNKNLLALDTDTSDRI
                     KAVKNFLAVLSDSICSLFIVNSNVASISLGNESFSTDEDLEYGYLMNTGNHYDVYLPP
                     ELFAQAYKLNNKEMNAQLDYLNRYAI"
     gene            36945..38186
                     /gene="agp"
                     /locus_tag="IT892_001185"
     CDS             36945..38186
                     /gene="agp"
                     /locus_tag="IT892_001185"
                     /EC_number="3.1.3.10"
                     /EC_number="3.1.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glucose-1-phosphatase/inositol
                     phosphatase"
                     /protein_id="HAP3134423.1"
                     /translation="MNKTLIAAAVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRA
                     PLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECP
                     PPYTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     SEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQE
                     PGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTS
                     PEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNE
                     RTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCP
                     IDADGFCPMDKFDSVLNEAVK"
     gene            complement(38224..38451)
                     /locus_tag="IT892_001186"
     CDS             complement(38224..38451)
                     /locus_tag="IT892_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134424.1"
                     /translation="MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWE
                     EGSDEVLVKAFAKTDKDSLFWGEQTIERKNV"
     gene            complement(38472..39068)
                     /gene="wrbA"
                     /locus_tag="IT892_001187"
     CDS             complement(38472..39068)
                     /gene="wrbA"
                     /locus_tag="IT892_001187"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HAP3134425.1"
                     /translation="MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMP
                     PQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGA
                     LYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPY
                     GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG"
     gene            39441..39614
                     /locus_tag="IT892_001188"
     CDS             39441..39614
                     /locus_tag="IT892_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415525.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HAP3134426.1"
                     /translation="MANHRGGSGNFAEDRERASEAGKKGGQHSGGNFKNDPQRASEAG
                     KKGGKSSHGKSDN"
     gene            complement(39871..41199)
                     /gene="rutG"
                     /locus_tag="IT892_001189"
     CDS             complement(39871..41199)
                     /gene="rutG"
                     /locus_tag="IT892_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization transport protein G"
                     /protein_id="HAP3134427.1"
                     /translation="MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMF
                     GATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNG
                     QGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
                     IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLG
                     LGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGR
                     NMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAML
                     LGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTL
                     VLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP"
     gene            complement(41220..41714)
                     /gene="rutF"
                     /locus_tag="IT892_001190"
     CDS             complement(41220..41714)
                     /gene="rutF"
                     /locus_tag="IT892_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415527.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization flavin reductase protein
                     F"
                     /protein_id="HAP3134428.1"
                     /translation="MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTD
                     TPPTLLVCLNRGASVWPAFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQT
                     GVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALM
                     RPAC"
     gene            complement(41725..42315)
                     /locus_tag="IT892_001191"
     CDS             complement(41725..42315)
                     /locus_tag="IT892_001191"
                     /EC_number="1.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonic semialdehyde reductase"
                     /protein_id="HAP3134429.1"
                     /translation="MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGP
                     TSANCSPARIVFTRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFP
                     HGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFT
                     GSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL"
     gene            complement(42325..43125)
                     /gene="rutD"
                     /locus_tag="IT892_001192"
     CDS             complement(42325..43125)
                     /gene="rutD"
                     /locus_tag="IT892_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein D"
                     /protein_id="HAP3134430.1"
                     /translation="MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVC
                     YDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYP
                     ASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPR
                     LEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSS
                     ELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL"
     gene            complement(43133..43519)
                     /gene="rutC"
                     /locus_tag="IT892_001193"
     CDS             complement(43133..43519)
                     /gene="rutC"
                     /locus_tag="IT892_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein C"
                     /protein_id="HAP3134431.1"
                     /translation="MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLF
                     ADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKP
                     ARFCIQCGLVKPDALVEIATIAHIAK"
     gene            complement(43531..44223)
                     /gene="rutB"
                     /locus_tag="IT892_001194"
     CDS             complement(43531..44223)
                     /gene="rutB"
                     /locus_tag="IT892_001194"
                     /EC_number="3.5.1.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxyureidoacrylate/ureidoacrylate
                     amidohydrolase RutB"
                     /protein_id="HAP3134432.1"
                     /translation="MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVS
                     TTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQP
                     QLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTG
                     IATNVCVESTLRDGFFLEYFGVVLEDATHQAGPKFAQKAALFNIETFFGWVSDVETFC
                     DALSPTSFAHIA"
     gene            complement(44223..45314)
                     /gene="rutA"
                     /locus_tag="IT892_001195"
     CDS             complement(44223..45314)
                     /gene="rutA"
                     /locus_tag="IT892_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309285.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein A"
                     /protein_id="HAP3134433.1"
                     /translation="MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDF
                     ALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAA
                     TIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKS
                     DFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFA
                     PTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQ
                     KDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDF
                     LSGIETFGERIQPLMQCRAHLPALTQEVA"
     gene            45602..46240
                     /gene="rutR"
                     /locus_tag="IT892_001196"
     CDS             45602..46240
                     /gene="rutR"
                     /locus_tag="IT892_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator RutR"
                     /protein_id="HAP3134434.1"
                     /translation="MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQI
                     AELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKL
                     EVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQ
                     HLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR"
     gene            complement(46280..50242)
                     /gene="putA"
                     /locus_tag="IT892_001197"
     CDS             complement(46280..50242)
                     /gene="putA"
                     /locus_tag="IT892_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001462364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /protein_id="HAP3134435.1"
                     /translation="MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQL
                     ENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRP
                     ETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
                     EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGK
                     LVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLE
                     EKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALH
                     PRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEESDRLEISLDLLEKLCFEPE
                     LAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGL
                     EGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQY
                     EFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSF
                     VNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDL
                     ANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPR
                     EVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAI
                     AEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNS
                     VLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGS
                     TEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAG
                     QRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHI
                     QTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYN
                     RNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPF
                     GGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAKYPVDAQLKAALTQPLNAL
                     REWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDAL
                     TQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDS
                     DQLRALCEAVAARDGTIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
                     "
     gene            50297..50506
                     /locus_tag="IT892_001198"
     CDS             50297..50506
                     /locus_tag="IT892_001198"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134436.1"
                     /translation="MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQ
                     LTFLKGATAKNVRECNLMKNSVAEH"
     gene            50665..52173
                     /gene="putP"
                     /locus_tag="IT892_001199"
     CDS             50665..52173
                     /gene="putP"
                     /locus_tag="IT892_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HAP3134437.1"
                     /translation="MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGP
                     FVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTE
                     YNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
                     ETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEV
                     IKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMT
                     WMILCLAGAVAVGFFGIAYFNDHPALAGAVNQNAERVFIELAQILFNPWIAGILLSAI
                     LAAVMSTLSCQLLVCSSAITEDLYKAFLRKHASQKELVWVGRVMVLVVALVAIALAAN
                     PENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWL
                     GLYEIIPGFIFGSIGIVVFSLLGKAPSAAMQKRFAEADAHYHSAPPSRLQES"
     gene            52716..53546
                     /locus_tag="IT892_001200"
     CDS             52716..53546
                     /locus_tag="IT892_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family protein"
                     /protein_id="HAP3134438.1"
                     /translation="MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLL
                     AAALCLGLGIFINETTGEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLE
                     QAVDSALQCGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLAT
                     AVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFD
                     MSAVLSTHSLFGTLMEGIFGYQEAPSVSEVAVWFIYLIPALVAFALPPRAGATASRSA
                     "
     gene            53604..54731
                     /locus_tag="IT892_001201"
     CDS             53604..54731
                     /locus_tag="IT892_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake system protein EfeO"
                     /protein_id="HAP3134439.1"
                     /translation="MTINFRRNALQLSVAALFSSAFMANAADVPQVKVTVTDKQCEPM
                     TITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMT
                     CGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDA
                     IKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHR
                     LEKALFGDNTTKGMDQYAEQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKI
                     SGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANSELLAKVDANFKKVDTILAKY
                     RTKDGFETYDKLTDADRNALKGPITALAEDLAQLRGVLGLD"
     gene            54737..56008
                     /gene="efeB"
                     /locus_tag="IT892_001202"
     CDS             54737..56008
                     /gene="efeB"
                     /locus_tag="IT892_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
                     /protein_id="HAP3134440.1"
                     /translation="MQYKDENGVNEPSRRRLLKVIGALALAGSCPVAHAQKTQSAPGT
                     LSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLT
                     QGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKM
                     TRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHA
                     ARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQ
                     FRVEFWDRTPLKEQQTIFGRDKQTGALLGMQHEHDVPDYASDPEGKVIALDSHIRLAN
                     PRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALE
                     EYVKPIGGGYFFALPGVKDANDYFGSALLRV"
     gene            56353..57417
                     /gene="phoH"
                     /locus_tag="IT892_001203"
     CDS             56353..57417
                     /gene="phoH"
                     /locus_tag="IT892_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
                     /protein_id="HAP3134441.1"
                     /translation="MVTSCTGHVLDNQRATTRGVFSSGSHLVTLHFQPHPFFSCVTDA
                     VNGARSRFSAFYPKANYGLQGSQPSDVRAHNRAANGACDEYKQLKVLSMGRQKAVIKA
                     RREAKRVLRRDSRSHKQREEESVTSLVQMGGVEAIGMARDSRDTSPILARNEAQLHYL
                     KAIESKQLIFATGEAGCGKTWISAAKAAEALIHKDVDRIIVTRPVLQADEDLGFLPGD
                     IAEKFAPYFRPVYDVLVRRLGASFMQYCLRPEIGKVEIAPFAYMRGRTFENAVVILDE
                     AQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLPRGVCSGLSDALERFEEDEMVGIVR
                     FGKEDCVRSALCQRTLHAYS"
     gene            complement(57467..57880)
                     /gene="pgaD"
                     /locus_tag="IT892_001204"
     CDS             complement(57467..57880)
                     /gene="pgaD"
                     /locus_tag="IT892_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     biosynthesis protein PgaD"
                     /protein_id="HAP3134442.1"
                     /translation="MNNLIITTRQSPVRLLVDYVATTILWTLFALFIFLFAMDLLTGY
                     YWQSEARSRLQFYFLLAVANAVVLIVWALYNKLRFQKQQHHAAYQYTPQEYAESLAIP
                     DELYQQLQKSHRMSVHFTSQGQIKMVVSEKALVRA"
     gene            complement(57882..59207)
                     /gene="pgaC"
                     /locus_tag="IT892_001205"
     CDS             complement(57882..59207)
                     /gene="pgaC"
                     /locus_tag="IT892_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine synthase"
                     /protein_id="HAP3134443.1"
                     /translation="MINRIVSFFILCLVLCIPLCVAYFHSGELMMRFVFFWPFFMSIM
                     WIVGGVYFWVYRERHWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRY
                     ENIEVIAVNDGSTDKTRAILDRMAAQIPHLRVIHLAQNQGKAIALKTGAAAAKSEYLV
                     CIDGDALLDRDAAAYIVEPMLYNPRVGAVTGNPRIRTRSTLVGKIQVGEYSSIIGLIK
                     RTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWTIFYEPRA
                     LCWILMPETLKGLWKQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYCLTTIWAF
                     TCLVGFIIYAVQLAGVPLNIELTHIAATHTAGILLCTLCLLQFIVSLMIENRYEHNLT
                     SSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRARWVSPDRGILRG"
     gene            complement(59200..61218)
                     /gene="pgaB"
                     /locus_tag="IT892_001206"
     CDS             complement(59200..61218)
                     /gene="pgaB"
                     /locus_tag="IT892_001206"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     N-deacetylase PgaB"
                     /protein_id="HAP3134444.1"
                     /translation="MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPW
                     PHNGFVAISWHNVEDEAADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGK
                     PLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDELVD
                     REYFATWQQVREVARSRLVELASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYET
                     AAEYRERIRLDAVKMTEYLRTKVEVNPHVFVWPYGEANGIAIEELKKLGYDMFFTLES
                     GLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKSPQRIMHIDLDYVYDENLQQMDR
                     NIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTR
                     SGVNIYAWMPVLSWDLDPTLTRVKYLPTGEKKAQIHPEQYHRLSPFDDRVRAQVGMLY
                     EDLAGHAAFDGILFHDDALLSDYEDASAPAITAYQQAGFSGSLSEIRQNPEQFKQWAR
                     FKSRALTDFTLELSARVKAIRGPHIKTARNIFALPVIQPESEAWFAQNYADFLKSYDW
                     TAIMAMPYLEGVAEKSADQWLIQLTNQIKNIPQAKDKSILELQAQNWQKNGQHQAISS
                     QQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDLIRPEFSTAWYPKND"
     gene            complement(61227..63650)
                     /gene="pgaA"
                     /locus_tag="IT892_001207"
     CDS             complement(61227..63650)
                     /gene="pgaA"
                     /locus_tag="IT892_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine export
                     porin PgaA"
                     /protein_id="HAP3134445.1"
                     /translation="MYSSSRKRCPKTKWALKLLTAAFLAASPAAKSAVNNAYDALIIE
                     ARKGNTQPALSWFALKSALSNNQIADWLQIALWAGQDKQVITVYNRYRHQQLPARGYA
                     AVAVAYRNLQQWQNSLTLWQKALSLEPQNKDYQRGQILTLADAGHYDTALVKLKQLNS
                     GAPDKANLLAEAYIYKLAGRHQDELRAMTESLPENASTQQYPTEYVQALRNNQLAAAI
                     DDANLTPDIRADIHAELVRLSFMPTRSESERYAIADRALAQYAALEILWHDNPDRTAQ
                     YQRIQVDHLGALLTRDRYKDVISHYQRLKKTGQIIPPWGQYWVASAYLKDHQPKKAQS
                     IMTELFYHKETIAPDLSDEELADLFYSHLESENYPGALTVTQHTINTSPPFLRLMGTP
                     TSIPNDTWLQGHSFLSTVAKYSNDLPQAEMTARELAYNAPGNQGLRIDYASVLQARGW
                     PRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQAAVLTHDVVEREPQDPGVVRL
                     KRAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYSPPLKDNWRGFAGFGYADG
                     QFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDNWRIGS
                     QLERLSHRVPLRAMKNGVTGNSAQAYVRWYQNERRKYGVSWAFTDFSDSNQRHEVSLE
                     GQERIWSSPYLIVDFLPSLYYEQNTEHDTPYYNPIKTFDIVPAFEASHLLWRSYENSW
                     EQIFSAGVGASWQKHYGTDVVTQLGYGQRISWNDVIDAGATLRWEKRPYDGDREHNLY
                     VEFDMTFRF"
     gene            64237..65595
                     /locus_tag="IT892_001208"
     CDS             64237..65595
                     /locus_tag="IT892_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HAP3134446.1"
                     /translation="MEKDYLRISSTVLVSLLFGLALVLVNSWFNQPGVEEVVPRSTYL
                     MVMIALFFIDTVAFIFMQLYFIYDRRQFSNCVLSLAFLSCLIYFVITVIIIQQIIEER
                     LTSSVVQNDIAIYYLFRQMSLCILIFLALVNKVSENTKQRNLFSKKMTLCISLFFVFG
                     GPIVAHILSSHYESYNLHIAELTNENGQVVWKASYVTIMIFMWLTLLSVNLYFNGLRY
                     DIWNGVTVIAFCAVLYNISLLFMSRYSVSTWYISRTIEVVSKLTVMVIFMCHIFSALR
                     VTKNIAHRDPLTNIFNRNYFFNELTVQSASAQKTPYCVMIMDIDHFKKVNDTRGHPVG
                     DQVIKTVVNIIGKSIRPDDLLARVGGEEFGVLLTDIDTERAKALAERIRENVERLTGD
                     NPEYAIPQKVTISIGAVVTQENALNPNEIYRLADNALYEAKETGRNKVVVRDVVNFCE
                     SP"
BASE COUNT        15952 a        16457 c        17004 g        16190 t
ORIGIN      
        1 tttgctctca ttcattcgta ttagctgcat ggttggcatg tcggctttgt cgtacacttt
       61 gttaaacagt ctggaggaaa taatgaaaga aaccgatatt gcaggcattt taacgtccac
      121 tcacaccatt gcgctggtgg gggcaagcga caaacccgat cgtcccagct atcgcgtgat
      181 gaaatatcta ctcgaccagg ggtatcacgt cattccggtt tcgccaaaag ttgccggcaa
      241 aacgctgctg ggccagaagg ggtatggcac gctggcagac gttccggaaa aagtcgatat
      301 ggtcgatgtt ttccgtaatt cagaagcggc gtggggcgtg gcacaggaag ctattgccat
      361 tggcgcgaaa accctctgga tgcaactggg ggtgattaat gagcaagcgg cagtactggc
      421 acgggatgcc gggttaaatg tggtgatgga tcgctgcccg gctattgaga tccctcgcct
      481 gggcctggcc aaataaaaaa tccccggaag gcaaaaacct tccggggatt tgttcaggga
      541 ttagttacgc agacgcgggg cctggagttg tttgcggatg gtctgcgcca gctcatccat
      601 ggatggctgt tcaggatgtt catcctgcaa ttcgctactt agctgggctt cagccaggta
      661 ggtatgaacc ggtaggccgt tatcgtcctc catcactacg tgataccacg gagcggcgcg
      721 aagctcgtca ttcaccgcca gctcatcagg cgacggttca gagagcgaat aaaccgggtc
      781 gatatccacg accactccga gataacctaa cagggaatgg cggacctgct ggccgatacc
      841 gaatttgctg gcaatcatag tcacctcccg ggaaatcttt acctttgata taagggtaaa
      901 attccacatt tcaagttaca tgacgcgaca ggcaaaccct ttcagatata gcccttccgg
      961 ataggtagcg atcaccggat gatcggctgc ctgacggaac tgctctataa attgtacatc
     1021 acgaccggca tcaattgcgg catccgcgat gattttctga aataaatcgc tggtcatcag
     1081 accggaacag gagaaagtca ggagaatacc gccttcattc agcagctgaa tcgccagcat
     1141 gttgatgtct ttataaccac gacacgcgcc catcaactgg cttttattct caacaaactt
     1201 cggcgggtcc atcacgataa cgtcaaattt ttcaccgcga tcgcgataag tacgcagcaa
     1261 tttaaagaca tcatcacgga caaactcagc cttgctcaga tccagtttgt tcagctcaac
     1321 gttctgccgt gcaatatcca gcgcttcctg ggaggtatca acgctgacaa cctggctgca
     1381 accgcccatc agtgccgata cggcgaaacc accggtatag gagaaacagt tcagcacacg
     1441 tttattttca acgtagcggc gggtagccag gcggctatca cgctggtcca ggtagtagcc
     1501 cgttttgtgt ccgtgctgaa tatccaccag cagtttcatt ccgtgctctt caatcggcag
     1561 cagggcaggt ggcaactcgc cggtgacggg gccctgggtc agctccattc cttctttttt
     1621 acgtaccgcg acgtcgctgc gatcgtaaat cgaacattcc gggtacagcg tttgcagggc
     1681 actaattaat gccgcgcgct gatattctgc cccagcactc agcagttgca gcaccagaaa
     1741 attaccgaaa cgatcgatag taatacccgg caggccatca gattctccgg cgattaaacg
     1801 atagctgtcg aggccatctt tttgcgccag ccagtcacgc catttttgtg cttgttgcaa
     1861 acggcgggaa aaaaaagcaa tgtcgataga ctcagacggg tcaaacgtcc agacgcgcgc
     1921 ccggatttgc gaagctggcg aataagcgcc gcgtgctaac cattttccct gatgatcaac
     1981 aatatcgatg gtttcaccga ggctggcttt accttccatg cgggcaacgg ccccggaaaa
     2041 gacccacgga tggcgacgaa gtaatgattt ttcgcgccct ttggctaaca ctaaacgtac
     2101 actcataatt tacttttctg tcgatgcaaa gaaatgggcg tcattgtccg gagttttcca
     2161 tggatttgca acgcgtccat taaggataag gagagcagca atgtcgaaag tctgcataat
     2221 tgcctgggtt tacgggcgag ttcagggcgt aggatttcgc tacaccacac agtacgaagc
     2281 gaaaagactg ggtttaaccg ggtacgccaa aaatcttgac gatggcagcg tggaagtggt
     2341 tgcttgcggt gaagaagggc aggtggaaaa attaatgcag tggttaaaga gtggcggccc
     2401 gcgttctgcg cgtgtagaac gggtgctcag cgagccgcat catccctcgg gggaattaac
     2461 cgattttcgt atccgttaaa tacattttac cggttttggc aggccagcaa ttttggtggc
     2521 ttgcttagcc ggacctttcg gaaacagtcg gtataaatag cggctgttac ctttttcttc
     2581 gccaaattta ttcgccatcg cttttaccag catacgaatc gccggagaag tattgaattc
     2641 cagatagaaa tcacgcacaa aacgcaccac ttcccagtgt tccggtgaca gcgaaatccc
     2701 ttcgttctct gcaatcacca cagccagcgg ctcactccac tggctgcttt ctttgagata
     2761 gccttcggta tccgtttcta tctctttacc ttcgaagatc agcataatta ttactacctt
     2821 aatcagactg gcggcagtgt aacaaaaaac aaagccccgc ataaagcgag gctatgaaag
     2881 tgttagcggg tgagattaat cgcggctagc gaagcccaga atgctcagca ggctgacgaa
     2941 gatgttgtac agcgaaacat acaggctaac cgtggcacga atatagttcg tctcaccgcc
     3001 atgaatgatg ttgctggttt caaacaagat agcgccagag gagatcagaa tgaagaccgc
     3061 gctgatcgcc agatgcagag caggcagctg caggaagata ttcgcaacca taccaatcag
     3121 caccaccaca atacccgcca tcagcatacc gccgaggaac gacatatctt tgcgggtggt
     3181 cagcacatat gcagagcagc agaagaacac taacgccgtt ccgcccagtg ccatagcgat
     3241 tacgtcaccc attccggcag acagataggt gttcagaata ggtccgagga tataacccag
     3301 aaaaccggta aaggcgaatg cggagataat cccggtcggc ttattcgccg ttttataggt
     3361 caggaacatc aaaccataca tacccaccag cgtcagaatc agacccggag atggcagcat
     3421 cagcaccgta ctggcagttg cggtaatcgc cgaaaaggcc agcgtcaggc tcagcagaaa
     3481 ataggtatta cgcagcacct tatgggtgct aagcagtgat gtacggtcat gtgaagaact
     3541 aacaatacga tccattgagt cactctctat gacagatgta attaattaag cagcataatg
     3601 ataatgcgta agggcaccca gaagttttac ccatctttac gcatttgatc tggaacaggt
     3661 ttaacagcgg attatcaggt cattaagcaa atataacgcc ctgagaattt cgacaggcaa
     3721 aagaaaaagg ggttagcatt tagctaaccc cttatcttat ttggcggaag cgcagagatt
     3781 cgaactctgg aaccctttcg ggtcgccggt tttcaagacc ggtgccttca accgctcggc
     3841 cacacttccg gaatgacgcg cactataaac atcccgatgc ggcgtgtaaa cccctaattt
     3901 gtttgtttgc ctgaaaaaca gccaaaagtg cattgatagc gtgaaataac agcagattga
     3961 tcatttcatc accatgaatt ccttctcttt tactcgttta gcaaccggct aaacatcccc
     4021 accgcccggc caaaagaaaa ataggtccat ttttatcgct aaaagataaa tccacacagt
     4081 ttgtattgtt ttgtgcaaaa gtttcactac gctttattaa caatactttc tggcgacgtg
     4141 cgccagtgca gaaggatgag ctttcgtttt cagcatctca cgtgaagcga tggtttgcct
     4201 tgctacaggg acgtcgcttg ccgaccataa gcgcccggtg tcctgccggt gtcgcaagga
     4261 ggagagacgt gcgatatgaa taacgaggaa acattttacc aggccatgcg gcgtcagggc
     4321 gttacccggc gcagctttct caaatattgt agtctggctg ccacgtcgct gggattaggc
     4381 gcgggaatgg caccaaagat tgcctgggcg ctggagaaca aaccgcgcat tccggtggta
     4441 tggatccacg gtctggaatg cacctgctgt accgaatctt ttatccgctc cgctcaccca
     4501 ctggcgaagg acgtcatcct ttccctgatt tccctcgatt acgacgatac tttgatggct
     4561 gccgccggaa cccaggcgga agaagtcttt gaagacatca tcacgcaata caatggcaaa
     4621 tatatcctcg cagtagaagg taatccgccg ctgggcgagc aggggatgtt ctgtatcagc
     4681 agcggtcgac cgtttattga gaaactcaaa cgtgccgctg ccggagccag cgcgattatc
     4741 gcctggggaa cctgcgcgtc ctggggctgc gtgcaggccg cgcgacccaa tccgacgcag
     4801 gcaacgccta tcgacaaagt catcaccgac aaacccatta tcaaagtacc tggctgcccg
     4861 ccgatcccgg atgtgatgag cgccatcatt acttacatgg tgacctttga tcgcttgcca
     4921 gatgtcgaca gaatgggccg tccgctgatg ttctatggtc agcgaatcca cgataaatgc
     4981 tatcgccgcg cccacttcga cgccggagag ttcgtccaga gttgggatga tgacgctgcc
     5041 cgcaaaggtt actgcctgta caaaatgggc tgcaaagggc ctaccaccta taacgcctgt
     5101 tcctccacac gctggaatga tggcgtttct ttcccaatcc agtctggtca cggctgcctg
     5161 ggctgtgcgg aaaatggttt ctgggatcgc ggttcgttct acagccgcgt ggtcgatatt
     5221 ccgcaaatgg gtactcattc caccgccgat accgtcggtt taaccgcgct tggcgtggtg
     5281 gcagcggctg ttggtgtgca cgcagtcgcc agcgccgttg accagcgcag acgtcataac
     5341 cagcaaccta cagaaaccga acatcagcca ggcaatgagg ataaacaggc atgagcactc
     5401 agtacgaaac tcagggatac accatcaata atgccggacg ccgcctggtg gtcgacccga
     5461 ttacgcgcat cgaaggccac atgcgctgcg aagtgaatat taacgatcag aatgtgatca
     5521 ccaatgccgt ctcctgcggc accatgtttc gcgggctgga gatcatccta caagggcgcg
     5581 acccgcgcga tgcgtgggcg ttcgttgaac gtatctgcgg cgtctgtact ggcgtacacg
     5641 ccctggcttc ggtttacgcc atcgaagatg ctatcggtat taaagtgccg gacaacgcca
     5701 atatcatccg caacattatg ctggcaacgc tctggtgcca cgatcatctg gtgcacttct
     5761 atcagcttgc cgggatggac tggatcgatg tgttagatgc gctgaaagcc gacccgcgga
     5821 aaacctccga actggcgcaa agtctctcct cttggccgaa atcatcccct ggctatttct
     5881 tcgacgtaca aaaccgcctg aaaaaatttg ttgaaggcgg gcagttgggg atcttccgca
     5941 atggctactg ggggcacccg cagtacaaac tgccgccaga agctaacctg atgggctttg
     6001 cccactatct cgaagctctc gatttccagc gtgaaattgt caaaatccac gcggtctttg
     6061 gcggtaaaaa cccgcatcca aactggattg tcggcgggat gccttgcgcc atcaacattg
     6121 acgaaagcgg cgcggtcggg gcagtcaata tggaacgcct gaacctggtg cagtcaatta
     6181 tcacccgcac ggcggacttc attaacaacg tgatgatccc cgacgcctta gccatcggtc
     6241 agttcaacaa accgtggagc gaaatcggca ctggtctttc tgataaatgc gttctcagct
     6301 acggcgcatt cccggatatt gccaacgact ttggcgagaa aagtctgctg atgcctggcg
     6361 gcgcggtgat taacggcgac ttcaacaatg tgctgccagt ggatttggtt gatccgcagc
     6421 aggtgcagga gtttgtcgac cacgcctggt atcgatatcc caacgatcag gtcgggcgtc
     6481 atccgttcga tggcatcacc gacccgtggt acaaccccgg cgatgtcaaa ggcagcgata
     6541 ccaacattca gcagctgaat gaacaggaac gctactcgtg gatcaaagcg ccacgctggc
     6601 gcggtaacgc gatggaagtg gggccgctgg cgcgcacgtt aatcgcttat cacaaaggcg
     6661 atgctgcgac cgttgagtcg gtcgatcgca tgatgtcggc gttgaacctg ccgctttccg
     6721 gtatccagtc aacgttaggc cgcattttgt gccgcgcgca cgaagcgcag tgggccgcag
     6781 gtaagttgca gtatttcttc gacaagctga tgaccaacct gaaaaacggc aatctcgcca
     6841 ctgcttccac ggaaaaatgg gaacctgcaa cctggccgac agagtgccgt ggtgtcggtt
     6901 ttaccgaagc gccgcgcggg gcgttaggcc actgggccgc cattcgcgat ggcaagattg
     6961 atctctacca gtgcgtggtg ccgaccacct ggaacgccag cccgcgcgat cccaaagggc
     7021 agattggcgc ttatgaagcg gcgctgatga acaccaaaat ggcgatcccc gagcaaccgc
     7081 tggagatcct gcgtactctg cacagctttg acccgtgcct cgcctgttca acacacgtgc
     7141 tgggcgacga cggtagcgag ctgatctccg tgcaggtgcg ttaacagcga aggagaatca
     7201 tcatgcaaca gaaaagcgac aacgttgtca gccactatgt ctttgaagcg ccagtgcgca
     7261 tctggcactg gttgacggtg ttatgcatgg cggtgttgat ggtcaccgga tactttatcg
     7321 gcaagccgct accttccgtc agcggcgagg cgacgtatct gttctatatg ggctacatca
     7381 ggttaattca cttcagcgcc gggatggttt ttaccgtggt tttgctgatg cggatctact
     7441 gggcttttgt tggcaatcga tactcccgcg agctgtttat cgtgccggta tggcgtaaaa
     7501 gctggtggca gggcgtgtgg tatgaaatcc gctggtatct gtttctggca aaacgtccga
     7561 gtgccgatat aggccataat cccatcgccc aggcggcgat gttcggctat ttcctgatgt
     7621 cggtctttat gatcatcact ggttttgcgc tgtacagcga acacagccag tacgctattt
     7681 ttgcgccgtt ccgttatgtg gtggaatttt tctactggac gggtggcaac tcaatggaca
     7741 ttcacagctg gcatcggctg gggatgtggc tgattggcgc gtttgtgatc ggtcatgtct
     7801 acatggcgct gcgtgaagac atcatgtccg acgacacggt gatctccacc atggtcaacg
     7861 gctaccgtag ccacaaattt ggcaaaataa gtaacaagga gcgttcatga gcgagcaacg
     7921 cgtggtggtc atggggctgg gcaacctgct gtgggccgat gaaggcttcg gcgtgcgggt
     7981 ggcggaacgg ctgtatgccc attaccactg gcccgagtat gtggagattg tcgatggcgg
     8041 tactcaggga ctgaacttgc tggggtatgt cgaaagcgcc agccatctgt tgattctcga
     8101 tgccattgac tacgggctgg aacctggaac gctgcgaacc tatgccggag aacgcattcc
     8161 ggcttatctc agcgcgaaga aaatgagcct gcatcagaac agtttctccg aagtgttggc
     8221 gctggcggat atccgcggac atctgccagc acatattgcc ctcgtcggtc tgcaacccgc
     8281 aatgctcgac gactacggcg gtagcctgag cgaactggca cgggagcaac tgcccgctgc
     8341 ggaacaggcg gcgctggcgc agcttgctgc gtggggaatt gtgccgcaac cggctaatga
     8401 atcgcgctgt ctcaattatg actgtctgtc gatggaaaat tacgaaggcg ttcgcttgcg
     8461 ccagtaccgg atgacacagg aggagcaggg atgagcaacg acacgccatt tgatgcgttg
     8521 tggcaacgaa tgctggcgcg cggctggacg ccagtcagtg aatcccgtct tgacgactgg
     8581 cttacgcaag cgccagacgg cgtggtgtta ttaagcagtg acccgaaacg cacgccagag
     8641 gtcagcgata atccggtaat gattggcgaa ttactgcgcg agtttcccga ctatacatgg
     8701 caggtggcga ttgctgacct tgagcagagc gaagccatcg gcgatcgctt tggcgtcttt
     8761 cgctttcctg ccactttagt gtttaccggc ggaaactatc gcggcgtgct gaatggtatt
     8821 cacccgtggg cggaactgat aaacctgatg cgcgggcttg tcgaaccgca gcaggagcgt
     8881 gtctcatgag cgaaactttt ttccatctgc tggggccagg aacgcaaccg aacgatgaca
     8941 gtttcagcat gaatccactg ccgatcacct gtcaggtgaa tgatgaaccg agtatggcgg
     9001 ccctggagca atgtgctcac agcccgcagg tgattgcgct gttaaacgag ttacaacatc
     9061 aactaagcga acgccaaccg ccgttgggcg aggtgctggc agtcgatctg ttaaatctca
     9121 acgccgacga tcgtcacttt atcaatacgc ttctcgggga aggggaagtg tcagtgcgca
     9181 ttcagcaggc tgacgacagt gaaagtgaaa tacaggaggc gatcttctgc ggattatggc
     9241 gggtgcgcag acgtcgcggc gaaaagttgc tggaggacaa actggaggct ggctgcgcgc
     9301 cgctggcgtt gtggcaggcg gcaacgcaaa atctcttgcc gacagattcg ctgttaccgc
     9361 cgcccattga tggcctgatg aatggcctac cgttggcgca tgagttactg gcacatgtac
     9421 gtaaccccga cgcgcagccg cacagcatta atctgacgca attacccatc agcgaggctg
     9481 atcggctttt tctctcacgt ctctgtgggc cgggaaatat tcagattcgt accattggct
     9541 atggcgagag ctatatcaac gccacggggt tacgccatgt ctggcattta cgctgtacgg
     9601 acaccttaaa aggcccgtta ctggaaagtt atgaaatctg cccaataccg gaagtggtgc
     9661 tggcagcgcc agaagatttg gtcgattctg cgcagcggct tagcgaggta tgtcagtggc
     9721 tggcggaagc tgcaccgacg taaaaagacg gtaagtatcg ctttcagtct tatgaatatc
     9781 gcaatcggcg aatacctctg gtcgtagagt ttcaggataa agagggagat ctaccattat
     9841 cgggttattt ttctctcttc gcctacagga gtgcgcatgt gggatgtcat tgatttatcg
     9901 cgctggcagt ttgctctgac cgcgctgtat cactttttat ttgtacccct taccctgggg
     9961 ctgatttttt tgctggctat tatggaaacc atttacgtgg tcaccggcaa aacaatctac
    10021 cgcgatatga cgcgcttctg gggtaagctc ttcggtatca attttgctct tggcgtggct
    10081 accggcctga ccatggagtt tcagtttggt actaactggt cattctattc caactatgtg
    10141 ggcgatattt ttggcgcacc gctggcgatg gaagcattaa tggccttctt cctcgaatcc
    10201 acctttgtcg ggctgttctt cttcggctgg caacggctga ataaatacca gcacctgctg
    10261 gtgacgtggc tggtggcgtt cggttcaaat ctctctgcgt tgtggatatt gaatgccaac
    10321 ggttggatgc aatacccgac cggtgcgcat tttgatatcg acaccctgcg tatggagatg
    10381 accagcttca gcgagctggt ctttaatccg gtcagccagg tgaaatttgt gcacaccgta
    10441 atggcgggct acgtgaccgg ggccatgttt attatggcga tcagcgcctg gtatttactg
    10501 cgcggacggg agcgcgatgt cgcattacgc tcgtttgcca tcggttccgt cttcggtact
    10561 ctggcgatta tcggtaccct gcaactcgga gacagttctg cgtatgaagt cgcgcaagta
    10621 caaccggtaa aactggcggc gatggaaggg gagtggcaaa cggaacctgc acctgcaccg
    10681 ttccatgtgg ttgcctggcc ggaacaggat caagagcgta acgcctttgc cctcaaaatt
    10741 cccgcgctgc tagggatcct cgccactcac tcattagata aacccgtgcc gggtctgaag
    10801 aatttgatgg ctgaaaccta cccacgcttg caacgcggac gtatggcctg gctgttaatg
    10861 caggaaatat cgcaaggcaa tcgtgagccg catgtgttgc aggcattccg gggactggaa
    10921 ggtgacctgg gctacggcat gttgctctcc cgctatgcgc cggatatgaa tcatgtcaca
    10981 gccgcacagt accaggcggc gatgcgtggc gcgatacctc aggttgcgcc ggtattctgg
    11041 agtttccgca tcatggtggg ctgtggttcc ctgctgctac tggtgatgct gattgcgctt
    11101 gtccagacgc tgcgtggcaa aatcgaccag catcgctggg tgctgaaaat ggcgctctgg
    11161 agtttgccgt tgccgtggat tgcgattgaa gccgggtggt ttatgaccga gtttggtcgt
    11221 cagccgtggg cgatacagga catcttaccg acatactccg cgcactccgc tttaaccaca
    11281 ggacaactgg ctttctcact gatcatgatc gtagggcttt acaccctgtt cttaatcgcc
    11341 gaagtctacc tgatgcagaa atatgcccgt ctggggccga gcgcgatgca gagtgaacaa
    11401 ccgacgcagc aacaggggta aaggagaaaa tcatgtttga ttatgaaaca ttgcgcttca
    11461 tctggtggct gctgattggc gtgatcctgg tggtctttat gatctccgac ggatttgaca
    11521 tggggatcgg ctgtctgctg ccgctggtgg cgcgtaatga tgatgaacgc cggatagtga
    11581 taaacagcgt tggtgcacac tgggaaggca accaggtctg gttgatcctc gctggtgggg
    11641 cattatttgc cgcctggccc agagtgtatg cagcggcgtt ttccggcttt tatgtggcga
    11701 tgatcctggt gctgtgctca ctgttcttcc gcccgctggc ctttgattat cgcggaaaaa
    11761 tcgccgatgc acgctggcgt aaaatgtggg acgccggtct ggtcatcggc agtctggtgc
    11821 cgccggtagt cttcggtatc gccttcggca acttgttgct cggcgtgccg tttgccttca
    11881 caccgcaatt acgcgtggag tatctcggca gcttctggca actgctgacg ccattccctt
    11941 tattgtgcgg attgctcagc cttgggatgg tgattttgca aggtggcgtc tggttacaac
    12001 tgaaaactgt tggtgtgatt catctgcgtt cacagctggc gaccaaacgc gctgcactgt
    12061 tggtgatgct gtgctttttg ctggcgggtt actggctgtg ggtcggtatt gatggctttg
    12121 tactgctcgc ccaggatgct aacggtcctt ccaatccgtt aatgaaactg gtggcagtgc
    12181 tacctggtgc ctggatgaat aattttgtcg agtcgcccgt tttgtggatc ttcccgctgc
    12241 tgggattctt ctgcccattg ctgacggtga tggcgattta tcgtggtcgc ccgggttggg
    12301 gatttttgat ggcatcattg atgcaatttg gcgtgatttt cacggcaggc atcacgctgt
    12361 tcccctttgt catgccgtca agcgtgagtc cgatctccag cctgacgttg tgggacagta
    12421 cttccagtca gctgacgctg agcattatgt tggtaatcgt gctgatattt ttgcccattg
    12481 tgttgctcta cactctctgg agctactaca aaatgtgggg gcgcatgaca acagaaactc
    12541 tccgccgtaa cgaaaacgag ttgtactaag gagcagaaac aatgtggtat ttactttggt
    12601 tcgtcggcat tttgttgatg tgttcgctct ccacccttgt gttggtatgg ctggacccgc
    12661 gtctgaaaag ttaacgaacg taggcctgat gcggcgcatt agcatcgcat caggcaatca
    12721 ataatgtcag atatgaaaag cggaaacata tcgatgaaag cgatcttaat cccattttta
    12781 tctcttctga ttccgttaac cccgcaatct gcattcgctc agagtgagcc ggagctgaag
    12841 ctggaaagtg tggtgattgt cagtcgtcat ggtgtgcgtg ctccaaccaa ggccacgcaa
    12901 ctgatgcagg atgtcacccc agacgcatgg ccaacctggc cggtaaaact gggttggctg
    12961 acaccgcgcg gtggagagct aatcgcctat ctcggacatt accaacgcca gcgtctggta
    13021 gccgacggat tgctggcgaa aaagggctgc ccgcagtctg gtcaggtcgc gattattgct
    13081 gatgtcgacg agcgtacccg taaaacaggc gaagccttcg ccgccgggct ggcacctgac
    13141 tgtgcaataa ccgtacatac ccaggcagat acgtccagtc ccgatccgtt atttaatcct
    13201 ctaaaaactg gcgtttgcca actggataac gcgaacgtga ctgacgcgat cctcagcagg
    13261 gcaggagggt caattgctga ctttaccggg catcggcaaa cggcgtttcg cgaactggaa
    13321 cgggtgctta attttccgca atcaaacttg tgccttaaac gtgagaaaca ggacgaaagc
    13381 tgttcattaa cgcaggcatt accatcggaa ctcaaggtga gcgccgacaa tgtctcatta
    13441 accggtgcgg taagcctcgc atcaatgctg acggagatat ttctcctgca acaagcacag
    13501 ggaatgccgg agccggggtg gggaaggatc accgattcac accagtggaa caccttgcta
    13561 agtttgcata acgcgcaatt ttatttgcta caacgcacgc cagaggttgc ccgcagccgc
    13621 gccaccccgt tattagattt gatcaagaca gcgttgacgc cccatccacc gcaaaaacag
    13681 gcgtatggtg tgacattacc cacttcagtg ctgtttatcg ccggacacga tactaatctg
    13741 gcaaatctcg gcggcgcact ggagctcaac tggacgcttc ccggtcagcc ggataacacg
    13801 ccgccaggtg gtgaactggt gtttgaacgc tggcgtcggc taagcgataa cagccagtgg
    13861 attcaggttt cgctggtctt ccagacttta cagcagatgc gtgataaaac gccgctgtca
    13921 ttaaatacgc cgcccggaga ggtgaaactg accctggcag gatgtgaaga gcgaaatgcg
    13981 cagggcatgt gttcgttggc aggttttacg caaatcgtga atgaagcacg cataccggcg
    14041 tgcagtttgt aatgcataaa aaagagcatt cagttacctg aatgctctga ggctgatgac
    14101 aaacgaagaa ctgtctaatg cgtagaccgg aaaaggcgtt cacgccgcat ccggccactt
    14161 tcagttttac tctttctcgg agtaactata accgtaatag ttatagccgt aactgtaagc
    14221 ggtgctggcg cgtttaatca caccattgag gatagcgcct ttaatattga cgcctgcctg
    14281 ttccagacgc tgcattgaca aactcacctc tttggcggtg ttcaagccaa aacgcgcaac
    14341 cagcaggctg gtgccaacag aacgccccac gaccgcggca tcactcaccg ccagcatcgg
    14401 cggcgtatcg acaatcacca gatcgtaatg gtcgttcgcc cattccagta attgacgcat
    14461 ccgatcgcgc atcagcagtt cagacgggtt aggtggcacc tgaccgcgag taatcacatc
    14521 aaagcctcct ttgccaaaat gctggatcac tttgttgagc tcatctttac ctgccagata
    14581 ttccgacaag ccatgttcat tactcacggt aaacaggtta tgcgaataac cacggcgtaa
    14641 gtcggcatca ataaataaca ctttttgatc ggactgggcg atcaccgctg ccagagttga
    14701 actgacaaac gttttaccac tgtctggcgt cgcaccggtg atcattagaa tgttattctc
    14761 cgtctccatc atagcgaaat gcagactggt tcgtagcgca cgtacggctt ccacagcaga
    14821 atccgccggg ttatccaccg ccaggaaggg gatattttta gtacgatggc gctgctgatt
    14881 agaaaataaa tttttcttac gcagacgggt gcgtttatcc agccactcgg acattgggat
    14941 agtggcataa acgctgatgc cgtgctcttc cagttgttcc ggggcttcta caccacgacg
    15001 caacatcgca cgcgccagca cggcacccac agaaataaac aggccaagaa taaaaccaag
    15061 caccacgttc aacgcttttt tcggtttcac tggctgcggc tgagtgactg ccgggtcgat
    15121 aatccgcacg ttaccaatgg cactggattt cgaaatactc aactcctgct ggcggttaag
    15181 taattgcaga tataccgcac ggcccgcttc tacgtcacga cttaaacgca acacttcctg
    15241 ttgggtggaa ggcattgccg atacccgctt attcaggcgt ttgcgttctt gctccagcgt
    15301 ctggcgtttt tccagcagcg cacgataagt tgggtgatct ttcttataca gctgggagat
    15361 ctctgcctcg cggaaggtca gctcattgag ttgattatca acgttcacaa tctgctcaag
    15421 aacggctttg gcttccaggt taaggtcaac cgaatcgcgc tgctggcgat aaacgttgag
    15481 tttttcttcc gcttggtcca gctcgctgcg cacttcaggt aactggcgct gtaagaattc
    15541 aaggctttgt gaatcctgcg ccgcctggcg agcgatattc tgttgcaaat agttgttagc
    15601 gatgctgttc agaatacgag taatcaactg gggatcatca ccagtcatgg taagttccag
    15661 catcccgctt tctttactgc gttcgctaac ggtaaaggtt tcctgcaatg cgttaatcgc
    15721 ttccagttcg gtacgctggc tcaggacaaa ctgtgttcct ggtttggcct taatgtccgc
    15781 gatagtcagc gcaacgccat ctttttccag acgctggccg accataccat tgacggtgaa
    15841 ctcttcacct tccagtgtat agtggccgtt ttccccaacc gtgagtgtca gttgctgatc
    15901 ctgaccattc agttgtggaa tatgcatcca gctgatcgcc agctcacctg gtttttcttt
    15961 ggttaatctc gcccagccgc gacccacaat cggaaaatac ttctgctcaa ctatgtcgcg
    16021 cagattcagt tcagcaatgg ttttaccgag aatcatgcgc gattgcagca gttggatctc
    16081 cggtgcagac tcgggcgatg agttagggat catatcgctc aggccgctga gaatggcgtt
    16141 gccctgtttt tgctcaacct ggaccagagt atctgcctga taaattggtg tgcttaacag
    16201 cgagtaagcg acagcgatca gcgtgaataa cgcggtcacg ctgataataa acttacggtg
    16261 atcccataac tcgccgacca gacgaagcag atcgatctca ttttcctgag tgctgcctgg
    16321 tggcgtattc atatttttag ttgtcatcgt attttataaa ctcaaattac cggctgaggc
    16381 gcttcgccca ttcctgactg gcgcgctcca acataccgta gacatgttca aatgcgtcct
    16441 gacttttacg atagggatcc gggatctctt tctgttccag ccattgccca aacagcattg
    16501 tcttcccgcg gacctcggga gcaattgcgg taacctgagc aatatgttcc gactccattg
    16561 ccagaatcag atcgtaattt cgtgccatct cagcagtgag cttacgtccg gcatgtcctt
    16621 caagagatac gccatgatta gcggcaacat ctgccgctgt cgcatctgca gggtgtttta
    16681 ccagaccatg aacacctgcc gatttgactt ttacgcccgg cagacgttta cgcagcaagc
    16741 gctcgccaat gggcgaacgg caaatgttgc cggtacaaac caccaggatt gagttaaatt
    16801 ttagttgggc catgtttgaa tccaccgtga agtctctgtc aggtcatgca ccccggaaat
    16861 cgtcggtacc agcagagaaa tcacacggtt ccaacgagcc agcggcgcgg tagtgacata
    16921 aacaatgtcg taaggttcaa gctggaattc cgttccgagt atcattgccg atgcgtcctt
    16981 cgcattcagc tgataaatat tggcgatttt gccattctgc ttgttttgcg ttgcacgaat
    17041 aacaaaaatc cccgtcgcat cagcgacatc ctgattcata ccctcagcgt tacccagcgc
    17101 ttccgccagg gtcataccgc tgcggtccat tttcagcgtg ctctgtttac ccacttcacc
    17161 catcacgaag actttcagat catcgttgcg cggaataaat aaaatatcgc ccgggtgcag
    17221 cagtttgttc tggcgcaagt cgccacgctg catcagcgca tagaggttca ctttggtctt
    17281 tacgccattc tgggtgagca ccacgttgcg ccagtctgca tctgcggtca gaccgcccgc
    17341 ggcgttaatc gcatccatga tggtcagagg aatattggta atcggctgct gacccgattt
    17401 gctgacttcg ccggtgacgt acgctttttg cgatcggaac gccgcgacgc tgacatcgac
    17461 ttgcgggctt tcaatgactg aatcgagacg cgctgtaatc tcgttgcgta cctgggtaag
    17521 tgttttcccg gccactttca ggcgaccaat ataggggtag aaaatcgcac catcggcgtt
    17581 aacccagttg ccggtatcac tggcgctacg gtattgccct gcgggggtgg ttagttccgg
    17641 gtgatcccag accgtaacca tcaacacatc accaatcccg atacgatatt catagtttgc
    17701 gatttgctgc tccagctccg ggttagcctg cgacataatc ggtttggcgc gcaactgatc
    17761 aatcaatcct ggcgtgacgg gatagatatt gaccattttg tccaggtcat actgattgtc
    17821 aggtagttca atgacatcct tgttactggt cgataaattc tgaccaggaa caagggtaca
    17881 tgctgtcaaa gacagaacag ccaatgtcag taccgaaaac ttaaaaatgt tctttttcat
    17941 tggtttatat ttatcagtca atgtaatgtt atgaattacg tcaggttatt gtccaaccgg
    18001 tacttctcgc tctgccgtca ttggatagag ctggtatttg cgtgacagca tttgtccacc
    18061 atcacgcgtc aatggtgtcc acgaaaccac cgcgcggttg cggttaggtc caatggtcat
    18121 caagtcgaat ggaatcgaga tataaaaacc tttactaaag ccgccttcgc cgtagtcatc
    18181 tttagatacg ttactgattg ccgcccatac ccctaccgcc acgccgctgt caaagcgttt
    18241 ggcgacgtcg atcgttgcgc ctttatcttt tgccagatat tgcccaacgc taagtttcat
    18301 cagtacgcca ttgagcgtcg gcgggttcca gtaagccgtc acgaaacctg ttggcgtgga
    18361 ataatcggtg aaacgcatca tgttgtccca gtcacgttgc ttcacgtagt taacgtccac
    18421 acccagcgcc cagcaggcat ctagcgggcg ataaagcagc tcggaaccga caccggcgta
    18481 catcgtttcc agataaccgc catacacctg gccatagaaa ccattgccta agtcagcaaa
    18541 atagttcgcc tgcaagttgt tgagataaac gtcattgcga acgtagtcac ggatatgcgt
    18601 gcgcacgcgg ggcagggtag agtccgcggg caacagcgaa gacttaaact tgtcgtagtt
    18661 gttgtaaata ttggtgaaaa taccgccatc aagcagcagg tggtcggtaa accagtagcg
    18721 ggcactggac atcagcccca gctggaacat atagaaatct tccgggccgc ccagcgactg
    18781 tgaaagtgtt gggttgaaag agtagctaaa gcgatcttca cgaatacggt agccccgacc
    18841 aaaggcagaa agatcttcag cttcaacacg ttgttgttgc agtggctctg attgaccagg
    18901 cgctgtacct gccagctgtt tgcgcaggct ggctacgtcg gtttcggtag tcaccatcgc
    18961 catatgctcg cgcttttgcg tcacgctaat cttctcaacg ccttgcggca ggttattcac
    19021 cagaatccgg ttggcacgat cgaccgcttc acgagagtca cggtatttgt attgctgacc
    19081 agacatatac agtgtcttat cgcgtagctg aatttctggc gcgtcaaagc ccgcgttata
    19141 cttcagggcg gtaagttggt ttgctaccgt ggtgtactgc aatccttcag attcaggcgc
    19201 aggttgatat gccggttttg gcgtatcgcg cagggcaggg cgcagatcgt tgaaattggt
    19261 ccgtaacgtg aagccaaaca tcaacgtgtt accgcgttca taactcaggt tgagatctgc
    19321 ccagctggca gcgcgataaa ctgcgccgac gttgaaatgg cttgcctgag gcagtttgcc
    19381 agcgaaatca ttctggtaat tgtttccatc gtattcgagt ttcagacgca ggggattcca
    19441 cggcgtttga tactcaatgc cgccaaagat ggaagccggg ccacgaaaga tatcgctaaa
    19501 gctgatatcg cccgcatcgt gagactctgc gcgatgacaa tatttatcgc tcacccggca
    19561 aaacgggttg gtaatattgc ccgcattacc ggcgtagccc catgccatcc cgagggtgaa
    19621 atcaaatggc cccgcttgct tgctggccac cagatactca ccgtcaaaca gacccgtacc
    19681 agcaatatca cgtttaccaa acgccacttg cggtagccag taaccttctt cccacaggcg
    19741 aagtttaaaa tcgaatgatt tgtctttgta tgactgatcg ccgctgaaat cttcccactg
    19801 gctatatttg cgtgtgcgca catccgtata acgaatggtg ccttccagcc atgggaacag
    19861 cgccacggag gtggagtaga accggtattg atcgttatcc cggtagttga cgctgaattc
    19921 accttccggt gcgatgcgcg catttggcat ctgcaacaat cctgtgccgc caaagtctga
    19981 ttgcgacgaa cccagcggat ccgggtaggt taatacttca gcatgacagg cactggagac
    20041 ggcaatggcc aggcagctta aaagataaga attcttcttc atcagtcagg aacacgttgc
    20101 gttaaaacag acacaatctg gtcatttaaa tcagcatatt tttcgggcag tacatgcgca
    20161 gaaaagccca accaaagctg gctgccaggc ggtggttcca catgtctttt attccacagg
    20221 gcaacagggg cgacgacagt ctcaccctca ggcgtaatca ccataacgtt attcttgtcc
    20281 gcgcctgcaa ggcgggggtg atcttgcaga taatcggtaa cgctacggcc tgcctgccag
    20341 ggcaattgcc cggccccaga aaccgcaccc agcagagtaa tagtcaccgg acgctgtacg
    20401 gtatagagcg tatagtcccc gaccaacggg ggattgctgt tctcatccac tcgtacaaaa
    20461 tcagggtcca gtttgaccgg taagcgacca gtgatattga gattgagtaa ctgctggcgc
    20521 acggatttaa tcgttgccgc cacatcgtcg tcagcttctg cttcccagga agcaagctgt
    20581 gccatgacat gttggtagtc tttaagcgct ttagctttcg ccgcagagtc ggtcagcaag
    20641 gcaccaggcc accagaggcg atcgcgcagt tgcggttgtg tcaccaactg gacaacattt
    20701 tccacggggc caacggaaag tgtctgttgt tcgccaggca gataaatagt caccgttcct
    20761 tgcgcaaagg catggggtgt cattacgtaa agtacgctgg caatgaaata cgactgtaat
    20821 ttattcatgg tgcgggttta agaaacgtca tttctacggg aataacccct gcgcctaaca
    20881 tttgccgact ttgacgaacc tggccagtag ccgaatcgac ccagaatgtg ttttgccact
    20941 gtttttctgg ccgcgtggaa gtcacctctt cctgccagac attacacagc acattgcgac
    21001 ccgcaatatt cagcgtctct aatccagcaa aggaaaaagt agaactcagg gtcgcagagc
    21061 gaaaatggtt gtcttcactc cagagaatat cgcgcgtcca gcggctgcca tcttttattg
    21121 ccagcgcgtt acgcagaggg tcctgcccgg aatttgtcac ttccagcaga ttattattaa
    21181 gtttgacggt ttttaaaaga cgtccattgt gggtaaccag catggcgtta tcctgggata
    21241 accatttgct ttgttcttgt tctatatatc ccagtaccac aaagattcgt tgcccttcat
    21301 taaggcgtaa atacatagtg gaataaggca acgcctggat ctgctgatcc gctacggtga
    21361 tatcctgatt atcgaaaagg ctggcgcgaa atgtatcgac catactttgc tggctgtgcg
    21421 tacatcccgc aagaaatagt gcgaaaatcg ataaaataag agggcgcacc tttaatcctt
    21481 gaaaggttaa ttaaaaaaat gcaaatctct aaagcccggt acgaatatcg caaccgggta
    21541 tcatttaact ttaattttga cgcgttaaag cagtattagc gtgtagtgga cgtggtggtt
    21601 gaggtgttat gagaaccgcc atcgccactg tcatttgctg caacaactgc caacgtcgcc
    21661 acaccaacag ccgttgccac accgacaact gtcgccgtgc cgacagcgcc agcagccacg
    21721 ccaccagtgg tagtagcagt cgtggttgcg ccggtagtgg tcgttgtggt gccagtagta
    21781 cccgtcgttg cctcggtccc gtttgttgct tcaggggcag caaacgcagc tggcgtcgtc
    21841 aacatgaagg ccataaggat tgcagaaagc ttgtgtttca taacttttcc tttattcatc
    21901 gcatggacaa tacgtacgct tgagatcagg attgtctact ttgagtataa catccttgtg
    21961 aaatctccct ttcctcatac cgcttgcact atatactgcg ggtaggaaag gcgcgcagag
    22021 ggaaatataa gattgttaac tatccccctc tggaaatacg acttgtgggc ataagataaa
    22081 tcttagcaaa atacaaatta aagataagga aattgttacg aaagctatta attattgttg
    22141 gtaatatagt ttcaagtggt actataactg gctgttaaat ggcatttata actattaggt
    22201 gcagagatat tcgcttaaat ggattagttt ctttgtggaa aagtaactga tgttataatg
    22261 tatgatgttg actattgcac tattccaata aaaccagtca gctttaaaca agcagcgtca
    22321 tattaagaga gataaacatt tgccgctgtt ggtcctcgca ggccatttac gcggcaaaat
    22381 tccacacgta atcctggtat aagcacttct gcgtcgcggg gagtgaatgc ggaaatatgg
    22441 acctgaactt ctttacgacc gtcggagggg ataatgaatc ctttgccgct tttgcgatca
    22501 aaggttttga caattcctgt cattttacgg gacaaacaaa ttccttactg aaaatactgc
    22561 gctgcactat acggggttaa taaaataaag ccagcgatat ttaagaccgc cggacggcta
    22621 aaataaaatt tgcttaatct caattatcat gcgttaatag ctgcgtcggt ttgaaagaca
    22681 gacagcatac aaagtagttt actaaagcag ttctcattat caggcattat ccccttcttt
    22741 tgagtctctc tcctgaacac taagtagttt ctgtattaaa gccctgtttg ccgaaaggcc
    22801 caaaatgaag gaagtaaaat atgtctaata aaatgactgg tttagtaaaa tggtttaacg
    22861 cagataaagg ttttggcttt atcactcctg atgatggcag caaagacgtt ttcgtccatt
    22921 tcaccgccat ccagagcaat gaattccgca cgctgaacga aaatcagaaa gttgaatttt
    22981 ctattgagca ggggcaacgt ggccccgcgg cagcgaacgt tgttacgctc taaggttgcc
    23041 attattactc aacatctcca tttccgctgt ccatgttgtc atggttcaca gtaccgcaca
    23101 tcggcattcg atgtgacgga gcgaaaccct ttgggcgcta agtgtatttt ttgtaaatcg
    23161 acgatgatca cctttgataa cgtcgcgctg caaatacgca ctgaccatgc gccgctggat
    23221 ttcacaaaat aatatcaggc tccctcgtgg agcctttttt atatctgcct tatttttctt
    23281 caacgctgta tgtatagtaa gcgataacct gttgattatt gaatctttcg gggagatggc
    23341 ttataacatt tcttacctga ccagggtacc gggaaccaac accttactgg cgtgttgctg
    23401 tcttttaaga ccagaagagg ttaacagtga atattgaaga gttaaaaaaa caagccgaaa
    23461 cggaaatcgc cgactttatc gcgcaaaaaa tcgccgagct gaacaagaat acagggaaag
    23521 aagtctctga aattcgcttc accgcacgag aaaaaatgac cgggcttgaa agttatgatg
    23581 tcaaaatcaa aataatgtga ttttgtgaac atcaccccgt gcgaggtgat gttccgcttg
    23641 ttgctaattt agtgaccaat cattggcgct tgtggaatta agcgtcggta caattcctcc
    23701 ggcaccgggc tttgccatac tcccgcatac attgcgtaac caatcaccgc aaacataatc
    23761 cccagaacca gtagcgtcat taaccagcca gacaacgcaa aggctttttt atttgccgca
    23821 ggtttttgca gtgaaaaggt caatgttgag gctaccggac atgactctac gcaagtcata
    23881 cagccggtac attccactgt tcgtacctga attaatttat cgaccgggat ccgtgatggg
    23941 caattttttg cgcatttgcc acagtcgata caactttcgg cattgcgacg aatcttaaac
    24001 ggcgacaata gcgaaaccac gcccatcagc gcgccatatg ggcaaagata acgacaccag
    24061 gcatggcgaa taaacaggct ggcaatcagc aaaacggtca cgctgattaa tgtcgcggtc
    24121 cccatatgac gaaagaaatc gagcatttta acgtccatca ccacgctgta gggcgacaac
    24181 ataaaatagt gaatcgcctg agcgggcatc aataacgcga tatagataaa aaaactcaac
    24241 agcaaatact tcacgccgcg cagaggaata tccagccagc ggggaaggac acattgccga
    24301 ccaaacagtt tgttaccgag atcgccgatt aattcagaaa gcgtaccaac cgggcataac
    24361 catgagcaaa aggccttttt gagtaataga ctgatgacga taaaagcgac caataacagc
    24421 atcgcggcgg cgtggacgga cggtaactga cctgttacaa ggctatattt cagattcatc
    24481 agcccggcaa tcggtagcca gccttcgata cctcccggtc tggcgacaaa tgtcgtgcta
    24541 cttgccgttt cgtaatagcg cacccaatac cagaacgtga tggcaatata aatattcatt
    24601 gccaacagta ataattgcgt cgctttacgc caggtcgtgg cattacgcca gtcattccac
    24661 ggtaatttgc cgcccgtcgt gcctggccgc cgctgccagc gggttctttt attctctgcc
    24721 atgattttgc cagtccgtta agttgtatac caaatgccac tattctagtt gttcttaact
    24781 ggctgatatt gattcaaatc gcgttcaggt ctttcttatg caaccatgct tccagagcgg
    24841 caacactgcg tgtaatttct tcgtgtggaa ggggggcaga taatggctgc tgctccagtt
    24901 gtgcgcatag ctggctggcg atatgcattc ccagactcga gcaactgctt tttagctgat
    24961 gcgcggcacg ctttattttc tcgctatcct gactggcgcg ggcaatgtcg atttcatcga
    25021 gaagcggcag ggcatgttgt gtaaataata ccagccattc gtggatcttc tccgtcccca
    25081 ttaactgagc atcttcattg agttgcgata catccagcga ttgatcatta ttgacttgca
    25141 gttggagata gtgcgccagt aactgaccga gcacttcacg cggcaccggt ttagggataa
    25201 tcccgcggaa taatgaactg gtacgctggc gcagcgtttc gtcaatgaca tgggcgctaa
    25261 agccaatcaa aaccagcgac ggatattgct gtgccagttg tcgggcaagc gtaatgccgt
    25321 cgatatccgg cagatcaaaa tccaccagtg cggcagcaaa cggttcgcta ttttgcagtg
    25381 tctctaaagc ctgcgcggca ttgccaacag caacaatctg cgcaccactg gttttcagca
    25441 tctcaatggt aattcgctgg gttagcgggt tatcttcaat taacagcaaa cgtaaaccgt
    25501 caagacgcac cgcctgattg actgtttttg gcacgggtgc cgtggcaaca cgtaacggca
    25561 agcgtaaaca aaaacagctt ccaacctccg gcgtgctggt ggcgctcagt tcgccgccca
    25621 tcgcctgggc cagacggcta ctgatagtca gtcccagccc ggtgccgccg cgtttgccgc
    25681 ttacctgcac aaatggctgg aagatttctg ccagtttcgc gggatcaata ccgcagccgc
    25741 tgtcttccac ttcgaccagc cattgctcgc catcagtgcg actacgcagg ataatgtacc
    25801 cttcgtcagt aaaacgcagg gcgttgctca acaggttggt tataacctga cgaatacgtc
    25861 gtgaatcgcc cattaacgcg cacggcatat catcggcaat tgccgttgcc aggcgaatcg
    25921 ggcgaccttt cacccgtccg ctcattaatt gcagggtact ttccagcagc gggcgcggtt
    25981 caaagggctc atcgctgacc gaaacattct tgccacctgc ttcgatagcg gaataatcga
    26041 gaatatcgtt gaggatggtc agcaacgatt caccagagtc agtaattgcc cgcaaatcat
    26101 cacgctgggc gttaagtgcg gggttatctg ccagcagttg agcagtgccg agaataccgt
    26161 acagcggtgt gcggatctca tggctcatcg ccgccagaaa cgccgatttt gcctggctgg
    26221 ctttttctgc ttccgcccgt gcctgtcggt gttctatcac cagttcctgc aattcagctg
    26281 tacgcgcttt gacctgcgcc gccagctgtt cgcggtggcg attcagtgca tgaacattgc
    26341 tgcgaaacgc atccatcagc cgcccgatgg tatccagctc ccgtacgcca gcggtttccg
    26401 ggaaagggga gtcaatatca ccgtccagca gccgttgcag cgcctgcgtt tgttcggcaa
    26461 gtggacgcgt gactgagcga taaaccacgc gccagaggat cagaatcagt gcgcaaagtg
    26521 aaaccatccc cagcaataac aggctgtatt gcccgcgtgc actcgctttt tccagatgcg
    26581 ccagtccgtg ctgattacgc agctcaatgg tgtcgaccag ctgactgact tcgctactaa
    26641 actgcgcgaa ctgggcgatg ttattttgtg cgagagtttg taggtgattg ctgatttcac
    26701 tgtcctgctg atacagcgcc agcaaatcgc tatattggct aacggtagtt aacgttgttg
    26761 cgacctgcgc acgaacaccc ggatcttcaa tgcgtatttg ccgacgttgc agaattttca
    26821 ccgcattatt gagctgcttt tccagcgttg gtgcattttt ctggatctgc tccagcccca
    26881 gattcatcac catttgctgc acccgcagag cgctaaggcg cagttcattc atctggttaa
    26941 catactcaag atcgatatca atcagccgat cgagtgcact ttcagcagcc tgacgctgat
    27001 cttgttcgat caaatcgtaa atcccggcct gggtcgctcc agcggaagtt gtcgcattat
    27061 tcgcctgacc ttgcgccagg cgtgcgatct catcggcggc agcgactatc tgctgactga
    27121 gttgctgttg ttgctggcgc agttgcaaac gctgccccac cagttcccct tgctgacgta
    27181 acgaacggga gatctcctgc tcctgttgtt caatagcggt ggtatcaaaa ccttgttccc
    27241 gtaacgcttg cagcaacgca ttaatcttca ggctttgtgc ggtgagcatt cgcccctgcg
    27301 cctgccacat cttttcgtta tcggcactgg tcaggttctg cgcggcgaaa agttcccagg
    27361 cgctggcttc gctcaactgg cgcgccatat tcatggtagg aatcaatgcc tgagtgttgt
    27421 ctttttccac ctggctgata aagcgcaggt tgtaccatcc caccagggta ctggtcaggg
    27481 ttaacagcgc catcagggca aagcccatcc agagtcttcg ggtcagggtt aaattcacgg
    27541 tcggtgcact ttaggtgaaa aaggttgagt cgcaaagcgg aatgcatcta gcataaagcc
    27601 ttattattga tgaggctatc atgcgcgtac tgctattttt acttctttcc cttttcatgt
    27661 tgccggcatt ttcggctgat aacctgttgc gctggcatga tgcgcagcat ttcacggtgc
    27721 aagcctctac gccgcttaaa gccaaacgcg catggaaact gtgcgcgctt tatcccagcc
    27781 tgaaagattc atattggtta tcgttgaact atggtatgca ggaggctgct cgccgctacg
    27841 gtgtggattt aaaagtgctg gaggcaggcg gctacagcca gttggctacc cagcaagcac
    27901 aaatcgacca gtgtaaacag tggggcgcag aggccatttt gctcggtagt agcacgacct
    27961 catttcccga cctgcaaaag caggtagcaa gtctgccggt gatcgaactg gtaaatgcta
    28021 ttgatgctcc ccaggtgaaa agccgcgttg gtgtgccctg gtttcagatg ggctatcaac
    28081 cggggcgata tctggtgcaa tgggcgcacg gtaaaccact gaatgtgctg ttgatgcccg
    28141 gacccgataa cgccgggggc agtaaggaga tggtcgaggg ttttcgcgca gccattgccg
    28201 gaagcccggt gcgtattgtt gatattgcgc ttggtgataa cgatattgaa atccagcgta
    28261 acctgttgca ggagatgctg gaacgccatc cagaaatcga cgtcgttgcc ggaacggcca
    28321 ttgcggcaga ggcggcaatg ggggaagggc gtaacctgaa aacgccgctt accgtggtgt
    28381 cgttttatct ttcacatcag gtgtatcgcg ggctgaagcg gggaagagtg attatggctg
    28441 ccagcgatca aatggtctgg cagggggaac tggcggttga gcaggccatc aggcaattac
    28501 aggggcaatc ggtttctgat aatgtcagcc caccgatttt agttctgacg ccgaaaaatg
    28561 ccgaccgtga acatattcgc cgctcgctgt caccaggggg atttcgtccg gtctattttt
    28621 atcagcacac atcagcggct aagaaataac cttcaccatg ttgcgtcacc agtaaatccg
    28681 cgctgagttt atgacgtaaa cgacgaatta acacatcgac ggtgcgcagg tcagggtttt
    28741 ccacccgacg cgcagaaagc atacgtagca gacgttcacg gctgagaatt tcgcccggat
    28801 tcgtcacaaa tgccaccaac atttcatact ctgcgcgggt cagtttaatc ggctcgccat
    28861 cccgctccag cgtatggcgc gacacattca ggcaataacc ggcaaagcga tagcagttgt
    28921 cctgagtgtg cggttgagct tgtcgcgcga ggtcgattcg ccagagcaga tttttcaccc
    28981 gtactaccag ttcgcgcagt tccagcggtt tggtgacgta atcgtctgcg cccatttcca
    29041 gcccaacaat acggtcaatc cgatcgctgc gtccggtaac cagaataatc cccaccgttg
    29101 agcgttctcg cagggcgcgg gttaacatca ggccattttc atcgggtaag ttgatatcca
    29161 gcagaattaa atctaccgac tgattctgca taatttcccg tagcccggca ccgctcgccg
    29221 taacggaaac ggtatacccc tcctgagtga agtaggattg taatcgcgcc tgggtaaccg
    29281 gctcatcttc aacaataaca atgtgatgtg gcatcagagg gttttactca ttctgttcat
    29341 atctgttcat attctgccgt aagccgttca tcctgaccag tgccgctgtt catatttgct
    29401 cattaagatc gcttcactaa accataattc tacaggggtt attatgcgga aactctggaa
    29461 cgcgctacgc cgacccagtg ctcgttggtc ggtactggcg ctggtcgcaa ttgggattgt
    29521 gattggcatt gcgctgattg tattgccaca cgttgggatc aaagtcacca gcacaaccga
    29581 attttgtgtc agttgccaca gtatgcaacc ggtgtatgaa gaatataaac agtcggtgca
    29641 tttccagaac gcctccggcg tgcgagctga atgccatgac tgtcatatcc cgccggatat
    29701 tccaggcatg gtgaagcgca aactggaagc gagcaatgat atctaccaga cctttattgc
    29761 tcactccatt gatacacctg aaaaattcga agccaaacgc gcggaacttg ccgagcgtga
    29821 atgggcgcga atgaaagaaa acaactcggc aacctgccgc tcctgccata actacgatgc
    29881 gatggatcat gcgaagcagc atcctgaagc agcacgtcag atgaaggtgg cagcgaaaga
    29941 taatcaatcc tgcatcgact gtcataaagg tattgcccac cagttaccgg atatgagtag
    30001 cggcttccgt aagcagttcg atgagctgcg agccagtgct aatgacagtg gtgacacgct
    30061 gtactctatt gatattaagc caatttatgc ggcgaaaggc gataaagaag cctctggttc
    30121 tctgctgcct gcttcggaag tgaaagtcct taaacgtgac ggcgactggc tgcaaattga
    30181 aattaccggc tggacggaaa gcgccggacg tcagcgtgta ctcacccaat tcccaggtaa
    30241 acgcatcttt gttgcctcga ttcgtggtga tgtgcagcag caggtaaaaa cgctggagaa
    30301 aaccaccgtt gccgacacca ataccgagtg gagcaagttg caggccactg cgtggatgaa
    30361 gaaaggcgac atggtgaacg atatcaaacc gatctgggct tatgcggatt cgttgtacaa
    30421 cggcacctgt aaccagtgcc acggcgcacc ggaaatcgcc cactttgacg ctaacggttg
    30481 gatcggcacg ctcaacggca tgattggctt taccagtctc gataaacgtg aagaacgcac
    30541 cttgttgaaa tatctgcaaa tgaatgcgtc tgacaccgca ggtaaggctc acggcgataa
    30601 gaaggaagaa aaataatgaa caataacgat ctctttcagg catcacgtcg gcgttttctg
    30661 gcacaactcg gcggcttaac cgtcgccggg atgctggggc cgtcattgtt aacgccgcga
    30721 cgtgcgactg cggcgcaagc ggcgactgac gctgtcatct cgaaagaggg cattcttacc
    30781 gggtcgcact ggggggctat ccgcgcgacg gtgaaggatg gtcgctttgt ggcggcaaaa
    30841 ccgttcgaac tggataaata tccgtcgaaa atgattgccg gattgccgga tcacgtacac
    30901 aacgcggcgc gtattcgtta tccgatggta cgcgtggact ggctgcgtaa gcgccatctc
    30961 agcgatacct cccagcgcgg tgataaccgt tttgtgcgcg tgagctggga tgaagccctc
    31021 gacatgttct atgaagaact ggaacgcgtg cagaaaactc acgggccgag tgccttgctg
    31081 accgccagtg gttggcaatc gacggggatg ttccataacg cttcggggat gctggcgaaa
    31141 gctattgcct tgcatggtaa tagcgttggt acgggcggag attactctac cggtgctgcg
    31201 caggtgatcc tgccgcgcgt agtcggttcg atggaagtgt atgaacagca aacctcctgg
    31261 ccgctggtat tgcagaacag caaaaccatt gtgctgtggg gctccgattt gctgaaaaac
    31321 cagcaagcga actggtggtg cccggatcac gatgtttatg aatattacgc gcagctaaaa
    31381 gcgaaagtcg ccgccggtga aattgaggtc atcagcatcg atccggttgt cacatccacc
    31441 catgagtatc tggggcgcga gcatgtgaag cacattgcgg ttaacccgca aactgacgtg
    31501 ccgctgcaac tggcgctggc acatacgctg tacagtgaaa acctgtacga caaaaacttc
    31561 cttgctaact actgtgtggg ttttgagcag ttcctgccgt atctgctggg tgagaaagac
    31621 ggtcagccga aagatgccgc atgggctgaa aaactgaccg gcattgatgc cgaaaccatt
    31681 cgtgggctgg cgcggcagat ggcggcgaac agaacgcaaa ttattgctgg ctggtgcgtg
    31741 cagcgtatgc agcacggtga acagtgggcg tggatgattg tggttctggc ggcgatgctg
    31801 gggcaaattg gcctgccagg tggtggtttt ggttttggct ggcactacaa cggcgcaggc
    31861 acgccggggc gtaaaggcgt tattctgagt ggtttctccg gctctacgtc gattccgcct
    31921 gttcacgaca acagtgacta caaaggctac agcagcacta ttccgattgc ccgttttatc
    31981 gatgcgatcc tcgaaccggg gaaagtgatc aactggaacg gtaaatcggt aaaactgccg
    32041 ccgctgaaaa tgtgtatttt tgccggaact aacccattcc atcgccatca gcagatcaac
    32101 cgcattattg aaggcttgcg caagctggaa acggttatcg ccatagataa ccagtggacc
    32161 tcaacctgcc gctttgccga tatcgtactg cctgcgacca cgcagtttga gcgtaacgat
    32221 ctcgaccagt acggcaatca ctccaaccgt ggcattatcg ccatgaaaca ggtggtgccg
    32281 ccgcagttcg aggcgcgcaa cgacttcgat attttccgcg agctgtgccg tcgctttaat
    32341 cgcgaagaag cctttaccga agggctggac gaaatgggct ggctgaaacg catctggcag
    32401 gaaggtgtac agcaaggcaa aggacgcggc gttcatctgc cagcgtttga tgacttctgg
    32461 aataacaaag agtacgtcga gtttgaccat ccgcagatgt ttgttcgcca ccaggcattc
    32521 cgcgaagatc cggatctcga accgctgggc acgccgagtg gcctgattga gatctactcg
    32581 aaaactatcg ccgatatgaa ctacgacgat tgtcaggggc atccgatgtg gtttgagaaa
    32641 atcgaacgct cccacggtgg gcctggctcg caaaagtatc cgttgcatct gcaatctgtg
    32701 catccggatt tccgacttca ctcgcagtta tgtgagtcgg aaacgctgcg tcagcaatat
    32761 acggtagcgg gtaaagagcc agtattcatt aacccgcagg atgccagcgc gcgcggtatt
    32821 cgtaacggtg atgtggtacg cgtctttaac gctcgcggtc aggtgttggc aggggcagtg
    32881 gtttctgacc gctatgcacc cggcgtggca cgaattcacg aaggggcatg gtacgatcca
    32941 gataaaggcg gcgagcctgg tgcgctgtgc aaatacggta accccaacgt gttgaccatc
    33001 gacatcggta catcgcagct ggcgcaggcg accagtgcgc acactacgct ggtggaaatt
    33061 gagaagtaca acggaacagt ggagcaggtg acggcgttta acggccccgt ggagatggtg
    33121 gcgcagtgcg aatatgttcc cgcgtcgcag gtgaaatcat gaccacgctg acagcacaac
    33181 agattgcctg tgtttacgcc tggctagcgc agttgttctc ccgtgagctg gacgatgaac
    33241 aactgacgca aatcgccagt gcgcagatgg ctgaatggtt ttcgttgctg aaaagcgaac
    33301 cgccgctcac tgcggcggtg aacgagctgg aaaaccgtat tgccacgctg acagtacgtg
    33361 acgatgcccg tctggaactg gccgcggact tttgcggcct gtttctgatg accgacaaac
    33421 aagcggcgct gccgtatgca tcggcctaca aacaggacga gcaagagatt aaacgcttgt
    33481 tagttgaggc agggatggaa accagcggca atttcaacga accggcagat catctggcga
    33541 tctatctcga attgctcagc catctgcatt tttcgctggg agaggggacc gttcctgcgc
    33601 gaagaatcga cagtttgcgg caaaaaacac tgacggcgct gtggcaatgg ttaccagagt
    33661 ttgttgcgcg ttgtcgtcag tatgacagct ttggttttta cgcggcacta agccagttat
    33721 tgctggtgtt agtggagtgc gaccaccaaa acagataacg tcgtttgtgc gcctgaaaag
    33781 acgcgtttag cgtcgcatca ggcattatgg cgcagttgcc ggatgcggcg tgaacgtctt
    33841 atccggccca caggaactgt aatctttgta gaccggttaa gatgcgtcat cgcatccggc
    33901 aaacacacat cacggatgag ctacaaaccg ggaaagccgc tggcgcagca ggcggttttc
    33961 ctgcttcagg tgcgcaatat catccattaa cgtcagcgcc accgcgatcc ccggccagtc
    34021 cagagccagt tcatgacgca ggcgtaccgc gcgttgcacc acaatggcgg catggtcgtc
    34081 aaatacccag gttgtttcct ggatctcacg cggttcaacc acccccaaac cgacaatttc
    34141 attcaactcc tcttcagaga tgccggtatg caggcaaaat tcggtaatag taaaagtcac
    34201 cgtaacatta gccattatgc tttcccccaa tctttacgtg gatcaaaaga cgactgggcg
    34261 tctgccagtt gctgccacag cgcggcagtg ttttcatccg gtttcggcgg catcacgatt
    34321 ttcagtaccg catacagatc gccggtctgt tttttgctca ccagaccttt gcctttaacg
    34381 cgcaatcgtt gcccggcctg gctgcctggc gggatagtca gcaaaatgct ttctttcagt
    34441 gttggaacgg tgactttagc acccagcgcc gcttcccacg ggctaaccgg caccacaatt
    34501 tccagatcct ggccgacaat atcaaacagc ggatgtggcg caatatgaat caccagccac
    34561 aaatcgccat ttggaccgcc gttttcgccc ggcgtcccct ggcctttcag acggatgcgt
    34621 tgaccattgc cgacgcccgc cgggatcttc acattcagcg ttttcggaat ttcctgttcg
    34681 atcatgccaa aggcgttata aaccggcagg ttatagctga tggtacgctt atgctcagta
    34741 agcgtttctt cgaggaatac cgccacttcg atttcaatat cgtggccgcg tgtggcgggg
    34801 cgttgacggc tctggcgggc atgctgaccg aaaattgacg agaagatatc gtcaaaatct
    34861 tcggcgttaa aactctgacc gtcgccatgg tggaactgac ggttaaattg cggatcgttg
    34921 cgatgttgcc acatctgatc atactcagcg cgacgttgtt catcacttaa cacttcccag
    34981 gcttcagcga cctctttgaa gcgggcttcg gcatccggtt ctttgctgac atcaggatgg
    35041 tatttgcggg caagtcgacg ataggcggtc ttgattgtct tgagatcgtc cgtcggtttc
    35101 acgcccatga tggcgtaata atcctttaat tccatagcgt tatctcgcgt aaatcaacac
    35161 aaattgaagg aacccctgta aggtaactcc tataagtgta gggtaatcct caaaatttca
    35221 tatgccaaca cagaatatgt tattgaaatc atcgcggaga ggaggtcgcc atcaagatgg
    35281 gttgctgaac atattttaaa caggtgaaaa agggtgagcg atttttgata gttgaaccag
    35341 gcactttaag tttaactagg gcgtcattat ttattaaatt ttatagacgc tatatatggg
    35401 tagtaatata catggaatta gttgcactgc aaataattat ttgaaacagg cctggaacga
    35461 tataaaaaat gagtacgaaa aaaatcaaac atattcaatc acgctttttg aaaacacact
    35521 ggtgtgtttt atgcggttat acaatgaact cagacgtaaa gtaaatgaag aggatactcc
    35581 atgtctggaa tgtgaatcac tagaaaaaga atttgaggaa atgcagaatg ataatgatct
    35641 atcattattt atgagaacat tgcgtactaa tgatacacaa atttattcag gggtttcagg
    35701 aggtattaca tatactatac aatatgttcg agatattgat attgttagag tgtccttgcc
    35761 gggcagggct tcagagtcta tcacagattt taaaggttat tattggtata actttatgga
    35821 gtatattgaa aacattaatg cgtgtgatga tgttttttct gagtattgtt ttgatgatga
    35881 aaatataagt gtccagccag agcggataaa tacgccggga atatctgatt tggattctga
    35941 cattgatttg tctggtatat cttttattca gcgtgaaact aaccaggcat taggattaaa
    36001 atatgctcct gtagatggcg atggatattg tctgttaaga gctatactgg ttttaaaaca
    36061 acatgattat tcatgggcgc tggtcagtta taagatgcaa aaggaagttt acaacgaatt
    36121 cattaaaatg gttgataaaa aaacgatcga ggctcttgtt gatacggcat tctataatct
    36181 cagggaagat gtaaagacgt tatttggtgt tgatctacaa tctgacaacc aaattcaggg
    36241 gcagagtagt cttatgtcat ggagctttct gttttttaaa aaacaattca ttgatagttg
    36301 cttgaataac gaaaaatgta tcctgcattt acccgagttt atatttaatg ataacaagaa
    36361 cttgcttgct ttagataccg acacgtcgga taggattaaa gcggtgaaga attttcttgc
    36421 tgttctttca gatagcattt gctcattatt tattgttaat agtaatgtgg catcaatctc
    36481 cttggggaat gaatcctttt caacagatga agatcttgag tatggttatt taatgaacac
    36541 tggcaatcat tatgacgttt acctccctcc tgaacttttt gctcaggctt acaagttaaa
    36601 caataaggaa atgaatgcgc aactcgacta tttaaatcgt tatgcaattt aatggcaaag
    36661 gcatatgcta aaaaccattg ttattagtct cacacttttt tattggtaaa tattgtctct
    36721 gtattggtaa cgccgcagat attctgttta gccacaggtg caattatcag cggcgtacgc
    36781 gaggcagggg ctaatcaggc atagtttgcg tcaaaccttg cctgtttttg aagatgtata
    36841 tagaaaaaca ggcgttcaac aagccatttt gcgaacctgt tcccggaaaa aagtcatatt
    36901 tctgtcacac tctttagtga ttgataacaa aagaggtgcc aggaatgaac aaaacgctaa
    36961 tcgccgcagc tgtggcaggg atagttttac tcgcttcaaa cgctcaggca caaaccgtac
    37021 cggaaggcta tcagctacag caagtgctca tgatgagccg ccataactta cgtgcgccgc
    37081 tggcgaacaa tggcagtgtg ctggagcagt cgacgccgaa taaatggcca gaatgggacg
    37141 tccccggtgg gcaactcacc accaaaggtg gcgtgctcga agtgtatatg ggccattaca
    37201 tgcgtgaatg gctggcagag caggggatgg tgaaatcggg ggaatgcccg ccgccgtaca
    37261 ccgtttatgc ctatgccaat agtctgcaac gtaccgttgc gaccgcacag ttctttatta
    37321 ccggcgcatt cccggggtgt gatattcctg tgcatcacca ggaaaaaatg ggcactatgg
    37381 acccaacctt taacccggtg atcaccgatg attccgccgc attcagtgaa caggcggtgg
    37441 cggcaatgga gaaagagctc agcaaactcc agcttaccga cagctaccag ctactggaaa
    37501 aaatcgttaa ctataaagat tcccctgcct gtaaagagaa acaacagtgt tcgctggtgg
    37561 atggcaaaaa tacctttagc gccaagtatc aacaagaacc aggtgtttcc gggccgctga
    37621 aagtcggcaa ctcgctggta gatgcgttta ctttgcaata ttacgaaggt tttccgatgg
    37681 atcaggtggc ctggggagaa atcaaatctg accagcagtg gaaggtgttg tcgaagctta
    37741 aaaacggcta ccaggacagc ctgtttacct caccggaagt ggcgcgcaat gttgcgaaac
    37801 cgctggtcag ttatatcgac aaagctctgg tcaccgatcg caccagcgca ccgaaaatta
    37861 cagtgttggt tgggcacgac tccaacattg cctctctgtt aacggcgctg gatttcaaac
    37921 cgtatcagtt gcatgaccag aacgaacgca cgccgattgg cggcaaaatc gttttccagc
    37981 gttggcatga cagcaaagcc aatcgcgatt tgatgaaaat tgaatatgtg tatcagagtg
    38041 cggaacagtt acgtaatgcc gatgcgttaa ccctgcaggc acctgcgcag cgtgtgacgc
    38101 tggaattaag cggttgcccg atagacgctg atggtttctg cccgatggat aagtttgata
    38161 gcgtgttgaa tgaagcggtg aaataacaga aaactccccc gcgagaagcg ggggagtcgc
    38221 tggttaaacg tttttacgtt cgatggtctg ttcgccccaa aaaagcgaat ctttatcggt
    38281 cttagcaaag gctttgacta acacttcatc actaccttct tcccaaatct tttccgccat
    38341 tttttcgtcg tacccggcga cttcgaaaat ggcctcggct atttccggcg acgtattgcg
    38401 cagagatgcc cattcaccga cgtgatgagc tttcgcttct tgagttggca tgcgtatcct
    38461 cctgttgaag attagccgtt aagtttaact gccagacctg cgacatattc cccttgataa
    38521 cgagcaatag acagttcttc ctggctgggc tggcgtgaac cgtcaccgcc tgcgatggtg
    38581 gttgcgccgt acggcgtacc gccgcgaacc tgtgaaacgt caaataattc ctgcgctgcg
    38641 tagccaatag ggacaattac catgccgtga tgcgcaaggg tcgtccaggt ggatgtgatg
    38701 gtttgttcct gaccgccgcc agtaccggtg gaactaaaga cgctcgccag ttttccgtat
    38761 agtgcgccgg aagcccacag gccgcccgtc tggtcgagga aggtacgcat ttgaccggac
    38821 atgttgccaa agcgggtagg tgtaccaaaa ataatggcgt cgtaatcggc cagttcttgc
    38881 ggggttgcaa ccggtgcagt ttgcgtttta ccgcctgctt tttcaaataa ttgcggcggc
    38941 atggtttccg gtacacgctt aacgacaact tcagcgccat ccactttgct tgcaccctca
    39001 gcgactgcgc gtgccatcgt ttcaatatgt ccgtacatgg aataataaag caccagaact
    39061 ttagccattt ctaaccactc ctcgtgttat ctctattccg tagcgattcg ctaccactta
    39121 tttaaagata agacgtcctt ttcagagtgc aaatttcaca accacttatt tgatttataa
    39181 caactttcac aagcacgtaa ttttgtcgca aaatgacaca tttttatctc atcgcgtttt
    39241 tttaatcata agagcggctt atggataatt attggagatg atatctattc tcgctaagaa
    39301 gctgttgcag gatattacca aacgcgggtc tgcccgcgtc agttcactaa gcttagtccc
    39361 acgtagcgaa aatatggcag ccgccatacg ccgcgttaat tctatgcaat atgatgtcta
    39421 tacccagacg gaggtcagta atggcaaacc atcgaggcgg ttccggcaat tttgcagaag
    39481 accgcgaaag agcatcagaa gcaggtaaaa aaggtggaca gcacagcggg ggtaatttca
    39541 agaatgaccc gcagcgcgca tctgaagcag gtaaaaaagg tggtaagagc agtcacggca
    39601 aaagcgacaa ctagccgggc taatcaatga cgaatgcatt tttgtctgta gctcgtcaaa
    39661 aagccatcac cgccggttac ccggtggttg atactgatga caaatgtaag cttgcctgat
    39721 gcgcgatgct tatcaggcct accagaagat tgcaatatat tgaatttgca ctgttttgta
    39781 ggccggataa ggcgtttacg ccgcatccgg catgaacaat gcgtacgttg tcaacaatct
    39841 gcaccgccgg taaccccggc ggttttctgt ttatggctcc tgatgaacaa cttctggcgg
    39901 tggaacgtca accaactttc tgcttaacaa cgcattgagt aaaatcgcgc caaaggttgc
    39961 tgtaccaatc cctcccaacg taaaaccgcc cagcgtgaga gcaaaatcac ccgcgcccag
    40021 cactaaggtt actgcgacca taatcaaatt accgttctgg cttaaatcga cacggttttg
    40081 tacccatatc cttgcgcctg cgacggcaat cagcccgaac acaacaattg atgcaccacc
    40141 aataaccgcg gccggaatgg tatgaatcag cgcaccaaat ttcggtgaaa agcccaacag
    40201 catggcgatg acggcagcag caacaaacac cagcgtcgag tagactttgg tcacggccat
    40261 cacaccgata ttttcagcat aggtggtcac gccgctaccg ccgacagagc cggaaagcat
    40321 cgttgccaga ccatcgccta cgaatgcccg ccccatatac gggtccatat tgcgtccggt
    40381 catcccggcg actgccttga gatgacctaa gttttccgcc accagaatca ccgccacggg
    40441 cgcaatcagc atcattgcct gaccattaaa agcaggagtg gaaaaatgtg gcagaccgaa
    40501 ccaggcagca tggctgacga gagtaaaatc gacggctttt cccagcccta aaacgttggt
    40561 catcacgcca tacagcagac aggcgacaat taatcctacg agaatcaata accgctggat
    40621 catgccacgg gtaaacaccg ccaccagccc aatacacagc accgtcatta ccgccatcca
    40681 gctatcaaag gccgaagccg atacactttt cactgcgata ggcgctaagt tcaggccaat
    40741 cgccatcacc accgcacccg tcaccaccgg cggcatcagt cgttcaatcc agcgcgtacc
    40801 gattttcatc accaccaggc caatgacggt ataaaccagc ccacaggcga taatcccgcc
    40861 cagcgcaatg ctgatattcg ggttaatgcc ctgaccgtta aagcccgtcg cggcgatcac
    40921 cacgccgaca aaagccgcgc tggagccgag ataactgggg acgcgcccgc cggtaataaa
    40981 gaaaaacagt aacgtgccga tccccgacat taaaatggaa agattgggat ccagccccat
    41041 cagaatcggc attaacaccg tcgcgccaaa catcgccacc gcgtgttgaa cgcccattac
    41101 tgccgtctga gcaaacggca atcgttcatc cggcgcgacc acgccgctct ctgtagaggt
    41161 cgattttaac tgccagtgag gaaaaccgaa cattgccatc agctgtctcc ttaaggaggt
    41221 taacaagcag ggcgcatcag cgcgtgataa ctgcgatcga accacaccag cccgtagggt
    41281 gtggtgtgac gatgaatcgc ttcgatggcg caaaacagaa tgtcgtgggt gccgacgctc
    41341 accacctggc tgatacggca gtcaaacgaa accagagcct cttccagttg cgggcatccg
    41401 gtcacccccg tctgccagcg ggcggcggca aagcggtgtt ccatgggcgt tttgccgcca
    41461 aaaaggtttg aaagcggctc ctgcccggcg ctaagtgtat ttacacacag cgttcgattt
    41521 tcattgaatg ccggccagac ggacgcccca cgattcaggc acaccagtaa tgtgggcggc
    41581 gtatcggtca cactgcagac ggcgctggcg gtgaacccgg cgcgcccggc tggaccgtcc
    41641 gtggtgataa tattgaccgc cgcgcccatg caggacatcg catcgcgaaa agtttgttga
    41701 tcgacaatgt tcatagtttg ctccttacaa cagcccgcag gcttcttcaa aggacagacg
    41761 tggcaggcgc gcataaagct tgctgctatc gccatagccg atattaatca gcagattgct
    41821 cttcagcgtg ctgcccgtaa aaaaggcgtc gtccacgtgt tgacggtcaa agcccgacat
    41881 cgggccggta tccagtccca gcgcccggca ggcgacgatc agataggccg cctgcatgga
    41941 actgttgcga aacgctgttt cttcggcaag ttgtgggctg gaggtaaacc aactgcgggc
    42001 atcaccgtgg ggaaacagta gtggtaaccg ttcataaaat tcactgtccc aggcgacgat
    42061 agcggtgacg ggcgcggtca gggttttttg cagattgccg ctggaaagtg ccgggcgcag
    42121 acgttctttt ccttctgccg tgcgggtaaa cacgatccgt gccggagaac agttagctga
    42181 tgtcggcccc catttcatca gggcataaat ctcccgtaac gtctcatcgc tgacgggtgt
    42241 ctcccgccag ccgttgtgag tgcgggcatc ggtgaacagg gtgctaagcg cacctgggct
    42301 aacggcttcg ttcatagcaa ttccttacag ggcggcttca cggtgatgta acaggctggc
    42361 aagcccgttg agtaacagag cattaaacgt ttcgggatcg gtcacgttgc aggcgtgtcc
    42421 gccatagggc atcaccattt tctggctatc gggcagggcg gcatgaagtt cactggaaca
    42481 tgctgttggc accagcagat catcactggc gcagatgatt tgcaccgggc agcggatgcg
    42541 atccgcatgg tgactaaagt cagcgcgttt gagggcgtta agtcgacgca gtaaattatt
    42601 tttgccctga aaatgcgcca gtgccagcgc gtcttctgcc tccaggcgag gtgcgcgggc
    42661 cgccatccag tcggcgggat agaggaacaa cggctgcgct tccacccatg cctgcgcgcc
    42721 gccgctatac agtaatcgtt cgcgaacctg aaaacagcgg cgcgtatggg cgtttattcg
    42781 tagccagccg ttaacgctga tcagcacagt taccgacgcg ggataatcca gcgccagctg
    42841 cattcccacc agcgcaccga gcgcatggcc gaccactgcg taatgctcaa tccctgcggc
    42901 taccagcgcc tgatgcagtt ccgctgccat ctgggcgata ctgtaatctt ctgccagcgt
    42961 gtcgggatta ttgccggtgc cgcgctggtc gtaacagact acctgatact cctgctccag
    43021 caccgccagt tgcggtaacc agtaactgcc gctaccccca agacccgaaa tcaacaccac
    43081 tacgggcgca tcagcataag ggggaggtga gagtgaaagt ttcatcgcgg cctcacttgg
    43141 cgatatgcgc aattgtggcg atttccacca gcgcgtcagg ttttaccagt ccgcactgaa
    43201 tgcagaatcg cgccggttta tcacccggaa aaaactcggc gtagatttcg ttaatcgcgg
    43261 cgtaattttt ccagtcggta ataaagatgc tgttgaaggt cacatccgcc atcgtgccac
    43321 ccgccgtctc gatcaccttg cggatagttt ccagaacgtg gcgggtttgc gcctttgggt
    43381 catcggcaaa cagcacgtta ttatgttgat caaaagccag cgtaccggag acatacacca
    43441 cgccatcagc cagcgtgccg ggaacgaagg gggccagcgg tgcgctgctg ccagcgggaa
    43501 taattacgga ttttggcatc gttaaactcc ttaagcgata tgagcaaagg acgtgggaga
    43561 aagcgcgtcg cagaatgttt cgacgtcgct gacccagcca aaaaaggttt cgatattgaa
    43621 caacgcggct ttctgcgcaa atttcggccc cgcctggtga gttgcgtctt caagcaccac
    43681 gccgaaatac tccagaaaaa agccgtcgcg tagcgtcgat tcgacgcaga cgttggtagc
    43741 gatgccggtg aaaaccagat ggcgtattcc gcggctgcgc aaaatgctgt ccagcggcgt
    43801 attgaagaaa ccgctgtagc gcggcttcgg cagcacaata tcgccaggct gcggcaccag
    43861 ttcatccacc agttgataat cccaggagcc tttcgccagc aatttcccct gcagctgcgg
    43921 ctgcttacgc atggttttca gggcgttcga tttatgaaaa ttcggtgagc cgggtccgcc
    43981 agcctcgaca tactgttcat cccagccatt ttgaaaccag atgatcagca tccctgccgc
    44041 tcgcgctgcg gtcacggcgg tttgaatgtt ggcaatgacc gggcgagtgg ttgagacatc
    44101 aaacccggcg agatctaagt agccgcctgg cgtggcataa gcgttttgca tatccaccac
    44161 gatcagcgca ctttgctgcg gatcgaaggt aatggcttcc ggtcgagcgg ttaaggtcgt
    44221 catcatgcca cctcctgagt cagcgcaggt agatgggcgc ggcattgcat cagtggttga
    44281 atgcgctcgc cgaaggtttc gattcccgac agaaaatcgt cgaaggttaa cagcacgcct
    44341 tcggcaccag gcacgcttgc gacttcatct aacatgcgcg cgacactggc gtaagaaccg
    44401 actaacgtcc ccatattgat gtttaccgcc gaagtgggat cggccatctg acgaacgttg
    44461 gtgtcagtac cggagcgggt atctttctga ctttgttcgg ttagccagct taacgcctct
    44521 tcatccgcgc ccgctttgta gtgttcccat ttggcgcgag cggcatcgtc ggtttcatcg
    44581 gcaatcacca taaacaacac ataagagcca acgtcgcgtc cggtttgctc tgcggcctgt
    44641 ttcatccgcg cagcggtcgg ggcgaaagcc gtgggtgtat ttacgccttt gccgaaacag
    44701 aagttgaaat cggcataccg ggcggagaac gccatgccag cgtcgctttg cccggcgcag
    44761 atcactttca tggggacact cggttgcgga ctcacgcgac aatcattcat ggtgaaaaaa
    44821 tcgcctttaa aatcgctttt ccccgtgccc cacaggtcgc gcagcacctg aacatattcg
    44881 gtgagatagt cgtaacgacg ggagaaatag tcatcgccag gccagatacc catctgctca
    44941 tactcgggct tttgccagcc agtcacgagg ttgacgccaa aacgcccgcc agagatggag
    45001 tcgatggttg cggccatacg ggcgacgatt gccggaggta acgttaaggt ggcagcagtg
    45061 gcgtaaatct gaatgcgcga ggtcacggcc gccagccccg ccatcaaggt gaacgactca
    45121 aggttgtgat cccagaactc agttttgccg ccaaagccac gcagtttgat catcgacagg
    45181 gcgaaatcga aatggtagtg ctccgctttt tgcacaatgg ctttattcag ttcaaaggtc
    45241 ggcatgtact gcggcgcgtg ggtcgaaatg agccagccgt tgttgccaat aggtacgaat
    45301 acgccaattt tcatcatcaa cctctcttcg tctcgtaaag tgaaagtcag acggggcgct
    45361 gcatcctgca tatccttttc agccgcgtat tggcttgttt gcaaagcgga tgccagtttt
    45421 taaaaagtta atgttattaa tctgttaaca ttacgttatc taaaatatct ggtaaaaagt
    45481 ggactaaacg gtcaaaacag ttgcacataa aacatgcatc tgtgcgcgat gagagtgcag
    45541 aaggtcgagg ccgggcgggg gttttgctat cctgttgcca atctacaaga ggggagagcg
    45601 catgacgcaa ggcgcagtga aaacaacggg taaacgttcg cgcgcagtaa gcgcgaagaa
    45661 aaaagcgatt cttagcgcag cactggacac tttttcacaa ttcggttttc acggcacaag
    45721 gctggagcag atcgcagagt tggcgggtgt ttcaaaaacc aatctgctgt attactttcc
    45781 gtcaaaagag gcgctgtata ttgccgtgct gcggcagatt ctcgatatct ggctggcacc
    45841 gttaaaagcg tttcgtgaag atttcgcccc gctggcggcg atcaaagagt acatccgtct
    45901 gaagctggaa gtctcacgcg attatccgca ggcttcgcgc ctgttctgta tggagatgct
    45961 ggcaggcgcg ccgctgttaa tggatgaact gacgggcgat ttgaaggcat taattgatga
    46021 gaaatcggcg ctgattgccg gttgggtcaa aagcggcaaa ctcgcgccga ttgatccgca
    46081 gcatttgatt tttatgattt gggcttccac tcaacattac gccgatttcg cccctcaggt
    46141 ggaggcggtg acaggcgcga cgttgcgcga tgaggtattt ttcaatcaaa cggttgaaaa
    46201 cgtgcagcgg attattattg aggggattcg accacgttaa agatgccgga ggaggttgta
    46261 acatcctccg gctacctgtt taacctatag tcattaagct ggcgttaccg ccagcggcag
    46321 cggtattcac actcagcgaa cgctcgatat acagccgttc cagaaggata ttgctttcgc
    46381 cacgggcaaa accctgcacc gaaacaattg tgccatcccg cgcggcaact gcttcacaca
    46441 atgcgcgaag ctgatccgaa tcaccgtgga agatcaccgc atcaaacggt tgagcggtta
    46501 tattttccgc tttcgccagt tgaatacgtt cgctgactgc cgatggcaat gccttcacta
    46561 actgacgatg cagcgcgtca tccggccaca gtacctggct gcccaccgcc agcacggcgg
    46621 cgagctgagt cagcgcatcc tgctcatcat cggcaataca caacacgcgc tcacgcggca
    46681 gcagcgtcca ggtgttgcgt tcacccgtcg gccccggcag caatcgttgt gttcctgcct
    46741 gcgccagctc gccatattgc gtacataacg cctgcaattc tggacgattt gctgcccatt
    46801 cccgcagtgc atttagcggc tgagtcaatg cggctttcaa ctgcgcatcg accggatact
    46861 ttgcatcctg acgcgcgagc gtcactgcca gcgcactttc cgggcgattc gccagcagac
    46921 ggtagagata gagcggaccg cctgctttcg gcccggtacc ggacaaccct tcgccgccga
    46981 acggctgcac accaaccact gcgcccacca tattacggtt aacatacagg ttaccaacat
    47041 gggccgagcc agtgacctgg gcgatggttt catcaatgcg cgtatggacg ccaagcgtca
    47101 gaccataacc ggaagcgtta atctgctcga tcagctctgg tagctggtta cggttgtaac
    47161 gcaccacatg cagcaccgga ccaaagacct ctttttgcaa ttcggcaaag tcatccagtt
    47221 cgatcagcgt cggggcgaca aaggtgccgc tttgccattc acgggcatct tcgctgtttt
    47281 cccgcaccgc ctggaacacc ggacggcctt tgctacgcat ggtctgaata tggcgctcaa
    47341 tattggcttt cgcttcgcta tcaatcactg gaccgatatc ggtggtcagg cgacccggat
    47401 tacccatccg gcattcggcc attgcgccgc gcagcatttt caacgtgtgg tcggcaatct
    47461 catcttgcag gcacagcacg cgcagcgccg aacaacgctg acccgcactg tcgaacgccg
    47521 aggccagtac atccacgacg acctgttcgg tcagtgctga agaatcgaca atcatcgcgt
    47581 tcatgccgcc ggtttcagcg atgagcggaa tagggcgacc ctgagcgtcc aggcggctgg
    47641 cgatattgcg ctgcagtaac gtagcgactt cggttgaacc ggtaaacatc accccgcgca
    47701 cgcgatcatc acccgtcagt tgtgcgccca cggtttcacc ccgacctggc agcaattgca
    47761 ccacgcctgg cggtacaccc gcttccagca aaatggcgat cccttgcgcg gcaatcagcg
    47821 gcgtttgttc tgccggtttt gccagcacgc tgttacctgc cgccagtgcg gcggcgatct
    47881 gcccggtgaa aatagccagc gggaagttcc acggactgat acacaccaca ggccctaatg
    47941 gacggtgggt ttcgttagcg aaatcatccc gcacctgtcc ggcgtagtag tggagaaaat
    48001 cgaccgcttc gcgcacttcg gcaatggcgt tactgaaggt ttttccggcc tcacgcacca
    48061 gaataccaat cagttgctgc atctggcttt ccatcagcac ggcagcgcgg tgcaaaatcg
    48121 ctgcgcgttc agccggaggc gtggcaaacc agattggcgc gttattaacc gcactttcca
    48181 gcgcctgttc tacttcacgc ggcgtggctt cacgcacata gcccacaata tctttcggtt
    48241 ccgcagggtt aataacgggc gacatctcac ctgccgctac cggttgttcc agcattggca
    48301 aggcctgcca tttttgcagt gcactattga gcagggcaga ggagagcgag gccaggcggt
    48361 gttcgttagc gagatccagc cctgccgagt tgtcgcgccc gtgaccgtaa agatcgcgcg
    48421 gcaggggaat tttcggatgc ggtaatccag tttgcccttc ctgttgcgcc agtttttcta
    48481 cagcagtgac cggatcggcg accagttcat ccagtggcaa agaggtgtcg gcaatacggt
    48541 taacaaacga ggtgttagca ccgttttcca gcaggcgacg caccagatac gccaacagcg
    48601 tttcatgtgt gccaaccgga gcataaatac gacacggacg gttaagtttg ccgtcggcaa
    48661 ctttcccggt gacctgctca tacagtggct cgcccatacc atgcaggcac tggaactcgt
    48721 actgacccgg gtagtagttc tgccccgcca gttgataaat cgccgccagc gtatgggcgt
    48781 tgtgcgtcgc gaactgcggg tagattagat tcggcaccgc cagcagcttt ttcgcacagg
    48841 cgagataaga aacgtcggta tacaccttgc gggtataaac cggataacct tcaaggccgt
    48901 ccatctgcgc acgcttaatt tcactatccc agtacgcgcc tttcaccagg cgaatcatca
    48961 gacggcgacg gctgcgggtg gcgagatcaa tcaggtaatc gatcaccaac gggcagcgtt
    49021 tttgataagc ctgaataaca aaaccgatgc cgttccagcc tgccagttcc ggctcgaaac
    49081 agagtttttc cagcagatcg agggagatct ccaggcgatc ggactcttcg gcgtcaatgt
    49141 tgataccaat atcgtactga cgcgccagca gggtgagtga tttcagacgc gggtaaagct
    49201 cttccattac ccggtcatac tgggcgcggc tataacgcgg atgcagcgcc gacagtttga
    49261 ttgaaatgcc cggcccttca tagatgccac gaccgttaga cgctttaccg atggcgtgaa
    49321 tcgcctgctg ataggaaacc atatacgcct gtgcatctgc ggcggtcagc gcggcttcgc
    49381 ccagcatatc gtaagagtaa cggaaacctt tctcttccag cttgcgggca ttggctaacg
    49441 cttccgcgat ggtttcgcca gtgacgaact gctcacccat caggcgcatc gccatatcca
    49501 cacctttgcg gatcagcggc tcaccgcttt taccgataat gcggttcagc gagcgggaga
    49561 ggctggcttc gttatgggtg gaaaccagtt tgccagtaaa cagcagcccc caggtggcgg
    49621 cattaacaaa cagtgacggg ctacgaccaa tgtgtgactg ccagttaccg ttgctgattt
    49681 tgtcgcgaat taacgcgtcg cgggtggctt tgtcgggaat acgcaacaac gcttccgcca
    49741 gacacatcag cgccacgcct tcctgcgatg acagcgaaaa ctcctgcaat aacccctgga
    49801 ccatacctgc gcgaccactg gcattttttt gattacgcag tttatcggcc agctgatacg
    49861 ccagtttgtg cgcctgttca gcaactggct gcggcaggcg ggcttgttcc agcagcatag
    49921 aaaccgcttc ggtttccggg cggcgatagg ccgcggtgat cgcggcgcgg gaaaccgact
    49981 ggggcaatat ttgctcggca aagtcgagga atggctggtg tggttcctct gccggagtcg
    50041 gtgcttcatc gctctcattg gccgcgccag aaagcagcgc aggtagctcc ggcagagtat
    50101 cgctgttttc cagttgttcg agataagaaa aaatcgcctg cttaattaac cagtgtggtg
    50161 tgcgatcgat acgtgtcgcg gcagacttaa tacgctcacg cgtcgcgtcg tccagcttaa
    50221 cccccatggt ggtggttccc atgccattac tcctgttgtt cagaaaggtg caacttaacg
    50281 ttatcgtgaa atatccatga tgttgcaact ttgtgcaacc atgttaaatg tgacatgcgt
    50341 agcaagctta aaaatgaatg aaatgttaat aaaagaaatc gatatgacag ggattaaaaa
    50401 aataactcag actttttctc tgcggcagtt aacatttttg aaaggtgcaa ccgcaaaaaa
    50461 tgtgagagag tgcaacctga tgaaaaatag tgtcgctgag cactaaaatt taatgtaaat
    50521 ggtgtgttaa atcgattgtg aataaccagc gcttccggca ggatacggtc gccctggtaa
    50581 aacataaact ctgttacccc gttccggtgg cagatataac ggcaagtttc gacattgccg
    50641 ataataattt tttggagact ttagatggct attagcacac cgatgttggt gacattttgt
    50701 gtctatatct ttggcatgat attgattgga tttatcgcct ggcgatcaac gaaaaacttt
    50761 gacgactata ttctgggcgg tcgtagtctt gggccattcg tgacggcatt atcggcgggt
    50821 gcgtcggata tgagcggctg gctgttaatg gggttgccgg gcgctgtttt tctttccggg
    50881 atttccgaaa gctggatcgc cattggcctg acattaggcg cgtggattaa ctggaagctg
    50941 gtggccgggc ggttgcgtgt gcataccgaa tacaacaata acgccttaac actgccggat
    51001 tatttcaccg ggcgctttga agataaaagc cgcattttgc gcattatctc tgcgctggtt
    51061 attttgctgt tcttcaccat ttattgcgct tcgggcattg tggcaggcgc gcgtctgttt
    51121 gaaagtacct ttggcatgag ctacgaaacg gctctgtggg cgggcgctgc ggcgacgatc
    51181 ctttacacct ttattggcgg tttcctcgcg gtgagctgga ctgacactgt acaggccagc
    51241 ctgatgattt ttgccctgat cctgacgccg gttatcgtca ttatcagtgt cggtggcttt
    51301 ggtgactcgc tggaagtgat caaacaaaag agcatcgaaa acgttgatat gctcaaaggt
    51361 ctgaactttg ttgccattat ctcactgatg ggttgggggc tgggttactt cgggcagccg
    51421 cacattctgg cgcgttttat ggcggcggat tctcaccaca gcattgtcca tgcgcgtcgt
    51481 attagtatga cctggatgat cctctgcctg gcaggggcgg tggctgtcgg cttctttggg
    51541 attgcttact ttaacgatca tccggcgttg gctggtgcgg taaatcagaa cgccgagcgt
    51601 gtgtttatcg aactggcgca aattctgttt aacccgtgga ttgccgggat tctgctgtcg
    51661 gcaattctgg cggcggtaat gtcaacctta agttgccagc tgctggtgtg ctccagtgcg
    51721 attaccgaag atttgtacaa agcgtttctg cgtaaacatg ccagccagaa agagctggtg
    51781 tgggtagggc gtgtgatggt gctggtggtg gcgctggtgg cgattgcgct ggcggcaaac
    51841 ccggaaaacc gcgtgctggg cttagtgagc tacgcgtggg caggctttgg cgcggcgttt
    51901 ggtccagtgg tgctgttctc ggtgatgtgg tcacgcatga cgcgtaacgg tgcgctggcg
    51961 gggatgatca tcggtgcgct gacggttatc gtctggaaac agttcggctg gctgggactg
    52021 tacgaaatta ttccgggctt tatcttcggc agtattggga ttgtagtgtt tagtttgctg
    52081 ggtaaagcgc cgtcagcggc gatgcaaaaa cgctttgccg aggccgatgc gcactatcat
    52141 tcggctccgc cgtcacggtt gcaggaaagc taagggactt agcctgcggc ggttttgttt
    52201 ggcttcagca gcgggttgcg ctcccttaat gtgcctcgcc atataaattg aatggtgcag
    52261 ggagcgcgca gggggcggcc aatcgccgcc gccccctgct gtcccggcct tcggggaacg
    52321 cttcagcgat tttgacgcca ccaacacccg agctgttatt atgttccggg caaaaagtta
    52381 gatttgataa tcgcggatgg acgaaattgc ttgatacacc cgcttatcag ttttacatgg
    52441 aagctctgat gcattgagtc tggacagttt tgtcggctgg atacggcgtt tacgcggcat
    52501 ccggcaagaa cacatggttc tttgcaaaca atcccatctt tctaccctgg aataatcgtt
    52561 tatatccctt ggcattacct ctctttgttt acattccaac atcattttat aaacattccg
    52621 cttgtgtttt tctttgctgt aatgataatc gctatcactg cgatttactt ttctttgcat
    52681 agattgactc agaaaaacgt ttaagggtgg gtggcatgtt tgttccgttt ctcattatgt
    52741 tgcgcgaagg acttgaagcc gcgctgattg tcagtttgat tgccagctat cttaagcgta
    52801 cccagcgagg ccgatggatt ggtgtgatgt ggattggcgt gttgcttgcc gctgcgttgt
    52861 gcctgggctt gggtatcttc attaacgaaa ccaccggcga atttccgcaa aaagaacagg
    52921 aactgtttga aggtatcgtg gcggtgatcg ccgtggtgat ccttacctgg atggttttct
    52981 ggatgcgcaa agtgtcgcgc aacgtcaaag tgcaactgga acaggcagtc gatagcgcat
    53041 tgcagtgtgg aaatcatcat ggctgggcgc tggtgatgat ggtctttttt gccgttgcaa
    53101 gggaagggct ggagtcggtc tttttcctgc tggcggcatt tcaacaagat gtcgggatct
    53161 ggccgccgct gggtgcaatg ctcggtcttg ctactgccgt ggtgctaggc ttcctgctct
    53221 actggggcgg tattcgcctc aatcttggtg cattttttaa atggaccagc ctgtttattc
    53281 tcttcgtcgc cgcagggctg gcagctggtg ccattcgcgc atttcatgaa gccggattgt
    53341 ggaaccactt tcaggaaatc gccttcgata tgagtgcggt gctctcaact cactcgctgt
    53401 ttggcacgct gatggaaggg atttttggct atcaggaagc gccgagcgtc agcgaagtcg
    53461 ccgtctggtt tatttatctc atcccggcgc tggtggcatt tgctctgcca ccacgcgcag
    53521 gggcgacagc gtctcgctcc gcgtaacaaa tacgacgcaa actcttgctt agttacaaca
    53581 tactttaaag ggatagtctc gtcatgacca ttaacttccg ccgtaacgca ttgcagttga
    53641 gcgtggctgc gctgttttct tctgctttta tggctaacgc cgctgatgtg ccgcaggtca
    53701 aagtgaccgt gacggataag cagtgcgaac cgatgaccat tacggttaac gccgggaaaa
    53761 cacagttcat tattcagaac cacagccaga aggcgctgga gtgggagatc ctcaaaggcg
    53821 tgatggtggt ggaagagcgg gaaaatatcg cccctggctt tagccagaaa atgacggcga
    53881 atttacagcc tggcgaatac gatatgacct gcggtctgct gactaacccg aaagggaagt
    53941 tgatcgtcaa aggtgaggca acggcggatg cggcgcaaag tgatgcgctg ttaagtcttg
    54001 gtggtgcaat tactgcatat aaagcgtatg tcatggcgga aaccacgcag ctggtgaccg
    54061 acaccaaagc ctttaccgac gcgattaaag caggcgatat cgaaaaagcg aaagcactgt
    54121 atgcaccgac gcgccagcac tatgagcgta ttgaaccgat tgctgaactg ttctccgatc
    54181 tggatggcag cattgacgcc cgtgaagatg attacgagca aaaagccgcc gacccaaaat
    54241 tcactggttt ccaccgtctg gaaaaagcat tgtttggcga caacaccacc aaagggatgg
    54301 atcagtacgc tgagcagctt tataccgatg tggtcgattt gcaaaaacgc atcagtgaac
    54361 tggctttccc accttcaaaa gtggtcggcg gcgcagccgg actgattgag gaagtggcag
    54421 ccagcaaaat tagcggtgaa gaagatcgct acagccacac cgatctgtgg gatttccagg
    54481 ctaacgttga aggctcgcag aaaattgtcg atttgctgcg tccacaactg caaaaagcca
    54541 actcggaact gctggcaaaa gtcgatgcca actttaaaaa ggtcgatacc attctggcga
    54601 aataccgtac taaagacggt tttgaaacct acgacaaatt gaccgatgcc gaccggaatg
    54661 cactgaaagg accgattact gcgctggcgg aagatctggc gcaacttcgc ggtgtgctgg
    54721 gactggatta agcgttatgc agtataaaga tgaaaacggc gtgaatgaac cgtcacgccg
    54781 acgtttactg aaagtgatag gtgcactggc gctggcggga agttgtccgg tcgctcatgc
    54841 acaaaaaacg caaagtgcgc cgggtacgct ttcaccggat gctcgcaatg agaaacagcc
    54901 gttttatggt gagcatcagg cagggatcct gacgccacaa caggccgcaa tgatgctggt
    54961 ggcgtttgat gtgcttgcca gcgataaagc cgatcttgag cggttgtttc gcttgttgac
    55021 tcagcgtttt gcttttctga ctcagggcgg agcagcacca gaaacgccaa atccgcgcct
    55081 gccaccactc gattccggca ttcttggcgg ctacattgcg cccgataatc tcaccatcac
    55141 gttatcggtg ggtcactcat tgtttgatga gcgctttggc cttgcgccac agatgccaaa
    55201 aaagctgcag aagatgacgc gtttccccaa cgactcgctg gatgcggcgt tatgtcatgg
    55261 tgatgtgttg ctacagattt gcgccaacac ccaggacacg gttatccatg cgctgcgcga
    55321 tatcatcaaa cacacgccgg atttgctcag tgtgcgctgg aagcgggaag ggtttatttc
    55381 cgatcacgcg gcgcgtagta aaggcaaaga gacgccgatt aatttgctgg gtttcaaaga
    55441 cggcactgcc aatcccgata gccagaatga taagttgatg caaaaagtgg tgtgggtaac
    55501 ggcagatcag caggagcctg cgtggacaat cggtggcagc tatcaggcag tacgcttgat
    55561 tcagtttcga gtggaatttt gggacagaac gccgctgaaa gaacagcaga cgatttttgg
    55621 ccgtgataag caaaccggtg cgctgctggg aatgcagcat gagcatgatg tgcctgatta
    55681 cgccagcgac ccggaaggga aggtgatcgc gctggacagc catatccggc tggcgaatcc
    55741 ccgcacggcg gagagtgagt ccagcctgat gctgcgtcgt ggctacagtt attcactggg
    55801 cgtcaccaac tccgggcaac tggatatggg gttgctgttt gtctgctacc aacacgatct
    55861 ggaaaaaggc ttcctgacag tacaaaaaag gctcaatggc gaagcgctgg aggaatacgt
    55921 taaacctatc ggcggcggtt atttttttgc gctgccgggg gtgaaggacg cgaacgatta
    55981 tttcggaagc gcgttattgc gggtttaatg tttttaggcg gataaggcat ttgtgcgcag
    56041 atgcctgatg cgacgcttgc gcgtcttatc atgcctacaa tcagtgcggg tttggtaggc
    56101 tggataaggc gttcacgccg catccggcga tcgtgcactg atgcctgatg caaatcctgc
    56161 tgaaagcaca cagctttttt catcactgtc atcactctgt catctttcca gtagaaacta
    56221 atgtcactga aatggtgttt tatagttaaa tataagtaaa tatattgttg caataaatgc
    56281 gagatctgtt gtacttatta agtagcagcg gaagttcccg gcagtgatag tcagtcacta
    56341 tggagatcgc ggatggtaac gtcctgtact ggacatgttt tagataatca acgcgccacc
    56401 actcgcggag ttttctcctc cggtagtcat ctcgtcactt tgcattttca acctcatcct
    56461 ttcttttcat gtgttaccga cgccgtaaac ggtgcgcgta gccgtttttc ggcattttat
    56521 ccaaaagcaa actatggctt acaaggaagc caaccctctg atgttcgtgc gcataatcgc
    56581 gctgccaacg gcgcgtgtga tgaatacaaa caactcaagg tgctctccat gggaagacaa
    56641 aaagcagtga tcaaagctcg tcgcgaggca aaacgtgtgc tgagacggga ttcgcgcagc
    56701 cataagcagc gtgaagaaga atcggtcacc tcgcttgtgc agatgggcgg cgtagaagcc
    56761 attggtatgg cccgcgacag tcgcgatact tcgcccatcc tcgcgcgaaa tgaagcgcaa
    56821 ttgcactatc tgaaggctat tgagagtaag cagctgatat tcgccacggg cgaagccggg
    56881 tgcggaaaaa cctggatcag cgcagcaaaa gcggcagagg ccctgataca taaggatgtc
    56941 gacaggatta tcgtcacccg tccagttctg caagccgatg aagatcttgg cttcttacct
    57001 ggagatatcg cagaaaagtt tgctccctat tttcgcccgg tctacgacgt gctggtccgg
    57061 cgcttagggg cttcctttat gcagtactgc ctgcgaccgg aaatagggaa ggtggaaatt
    57121 gcgccgttcg cctatatgcg tggacgtacc tttgaaaatg cagtcgtcat tcttgacgag
    57181 gcgcagaatg tgactgccgc gcaaatgaaa atgtttttaa cccgcctcgg ggagaacgtg
    57241 acggttatcg tcaacggtga tatcacgcaa tgcgatttgc ctcgcggcgt gtgctccgga
    57301 ttaagtgacg cgctggaacg tttcgaagaa gatgaaatgg ttgggatcgt ccggttcggt
    57361 aaagaggact gcgtacgttc ggcactttgc caacgtacgc tgcatgccta cagttaagtg
    57421 tgttatcggt gcagagcccg ggcgaaccgg gctttgtttt gggtgtttat gcccggacta
    57481 gcgctttttc tgaaacaacc atttttattt gcccctggct ggtgaagtgt acgctcatcc
    57541 tgtggctttt ttgtagttgc tgatagagct catcaggtat tgctaagctc tctgcatatt
    57601 cttgcggcgt atattggtag gctgcatgat gctgctgttt ttgaaaacgc agcttattgt
    57661 acagcgccca gacaattaac acgacggcat tcgccactgc cagcaaaaaa tagaactgaa
    57721 gtcggcttct ggcctcgctt tgccagtaat aacccgtcag cagatccatg gcgaataaga
    57781 atatgaacaa cgcaaataat gtccacaaga tggttgtggc aacataatca accagtaaac
    57841 gtactggtga ttgtcgggtc gtaataatta aattgttcat attaacctct cagaatcccg
    57901 cgatcgggac ttacccaacg ggcgcgttgc tttttaggca tcaacatgac tcgtgtaaat
    57961 gataccaatg tcgttgccag gctcagcatc cagaaaataa ccgggaacca aataatccag
    58021 aaaagcgatg aagtcagatt atgctcatag cgattctcga tcatcaggct gacaataaat
    58081 tgcagtaaac ataacgtaca caataatatt ccggcagtat gtgtcgcagc gatatgtgtc
    58141 aattcaatat ttaacggtac accggcaagt tggactgcgt aaataatgaa accgaccagg
    58201 caggtgaagg cccatattgt cgtcaggcag tattcaaaaa acagcggcca cattcgaaag
    58261 ttttctttgc gccacaacct tgtcatattt ttgaggaata cttctgcacc gccctgagcc
    58321 cagcgcaggc gctgtttcca cagccctttt aacgtttcag gcattaatat ccagcacagt
    58381 gcccgtggct cgtaaaaaat cgtccactga ttcaactgca gcttccagct aatatcaata
    58441 tcttcggtga tcatatcgtc actccagtaa cccacttctg ccagggcgct gcgacgaaat
    58501 gcggcaataa caccggaaac ggtaaatacg tttccataga tacgctgggt tcgcttgatc
    58561 aaaccaataa ttgaggaata ctcgccaacc tgaattttac ccaccagggt agaacgtgtt
    58621 cgaatacgag gattaccggt tacggcaccc acacgcgggt tgtacaacat cggttccaca
    58681 atatatgccg ccgcatcgcg gtctaataac gcatcgccat caatgcacac cagatattca
    58741 cttttcgccg cggcagctcc ggttttaagc gcaatggctt tcccctggtt ttgcgccaga
    58801 tgaatgaccc gcaaatgggg aatttgtgca gccatgcgat ccaggatggc acgggtttta
    58861 tctgttgaac cgtcatttac ggcaataact tcaatgttct cataacgctg tgctaaagcg
    58921 gcgtgtatgg tttcctcaac gtttttctcc tcattaaaac agggaatgat aatggagata
    58981 gacggattat ctttcaactg gggagctggt gcgttttctc cccacggcca gtggcgttca
    59041 cgatagaccc agaaatagac gccgccaaca atccacataa tggacataaa aaacggccag
    59101 aagaaaacga acctcatcat cagttcacca gagtgaaagt acgctacgca taggggtatg
    59161 cataacacca gacataatat aaaaaacgat acgatgcgat taatcatttt tcggatacca
    59221 ggctgttgaa aactcaggac gaataaggtc tatttcaggt tggttatgca gaaaattgtc
    59281 gggataataa ccatagtttt tcactccatt cagttgtaat aggctcatcc agtgagcgag
    59341 ttgttgcgaa gaaatagcct gatgctgacc atttttctgc cagttttgtg cctgtaattc
    59401 taaaatagat ttgtctttag cctgagggat gtttttaatt tgattggtca attgtattaa
    59461 ccattggtca gccgattttt ctgcgacacc ttccagataa ggcatagcca taatagcggt
    59521 ccagtcatag ctttttagga aatcagcata attctgtgca aaccaggctt cactttcagg
    59581 ttgtattacc ggaagtgcaa aaatatttcg tgcagtttta atatgtggac cgcgaatggc
    59641 ttttacgcgc gcactaagtt ctaaagtgaa gtcagttaac gcacgacttt taaagcgggc
    59701 ccactgttta aattgctccg ggttttgtcg aatttcgctc agactcccgc taaagcctgc
    59761 ttgctgataa gccgtgatag ccggtgcact ggcatcttca taatctgaaa gcaaagcatc
    59821 atcgtggaac aatatgccat caaaagcagc atgtccggca agatcttcat ataacatgcc
    59881 aacttgtgct ctgactctgt catcgaaagg agagagacgg tgatattgtt caggatgaat
    59941 ttgtgctttt ttctcccctg ttggtaagta ttttactcgc gttaatgtgg gatctaaatc
    60001 ccagcttaat accggcatcc acgcatagat gtttacacct gagcgggtac gtaattgcca
    60061 ggcaacccga ctaaaaatat ctgctttcat tggtagcaaa cgatttggaa accagacctc
    60121 tttgaccagc ccatcaccat cgggatcagc aaatgcctgc aaatacacgg ttgatatttg
    60181 catatctttc acccgctgaa ttagcacatc aatattgcga tccatttgct ggaggttttc
    60241 gtcataaacg taatcaagat cgatatgcat tatccgttgt ggtgattttt cctgtacggt
    60301 aataatttgc tgggcaaact cttttaatga gggattattg gcgattaata cccgcggaat
    60361 ggaatccaat tgcgacgcat ttgccaaacc tgattcaagg gtgaagaaca tgtcataacc
    60421 gagttttttt aattcctcta tcgctatgcc attcgcttcg ccataaggcc aaacaaaaac
    60481 gtgtggattt acctcaacct ttgtacgcag gtattccgtc atttttacag catccagacg
    60541 aattctttcc cggtattctg ctgcggtttc ataccgtgcg tggtcagtaa aatatgcacg
    60601 atttacatat acaggcaata agctgccggt ggcattagcc tgaataccgt agtgagaatt
    60661 ccatgtatga gaagcgagct caacgagccg ggaacgcgca acttctcgca cttgttgcca
    60721 cgtggcaaaa tattctcgat cgaccaactc atcgccaaat tttacttgtt tatccgctgg
    60781 cgtatcgacc caactgccga cgggggccca tacagcaggc cactggaagg cctgaagaat
    60841 tgggaagacg cgggtataaa aactctggta gccgtcatca aaagtcagca ctacagcttt
    60901 ttccggtagc ggttttcctc ctcgatgtgc ttcacgaatt tgagcaatac tgaccggttg
    60961 ataaccgttc tcgcgcagcc aggcaaattg ttcacgcagt gctgatgtcc gcactgacat
    61021 aaaacgctgg tcggcagctt cgtcttcaac gttatgccat gaaatcgcta caaaaccatt
    61081 atgcggccac ggttgctcgg cgagtaaaga ttcgcgatcc tgtggcggta taaatgatgt
    61141 tcttgactgg ctaatgcacg cggtgagcat aattatactc accagcatca ggagatattt
    61201 atttccatta cgtaacatat ttatccttaa aatctgaatg tcatatcgaa ttcaacgtat
    61261 aagttgtgtt ctctgtcacc gtcataaggt cgtttttccc agcgtagcgt tgcgccagca
    61321 tcaatcacgt cattccaact aatgcgttgc ccgtagccga gttgggtgac gacatccgtg
    61381 ccataatgtt tttgccagga ggcaccaaca cctgcgctga atatttgctc ccagctattt
    61441 tcatagcttc gccataacaa atggcttgcc tcaaatgccg gaacaatatc gaacgttttt
    61501 atagggttgt agtatggggt atcgtgttct gtattttgtt cgtaatacag actgggtagg
    61561 aaatcgacaa tcaaatatgg tgaagaccag atgcgttcct gaccctcaag tgagacttca
    61621 tgacgctggt tactgtcgga aaaatcagtg aaagcccagg agacaccgta cttacgccgc
    61681 tcattttgat accagcgaac ataagcctga gcactgttgc ctgtaacacc atttttcatt
    61741 gcccgtaatg gaacgcggtg agagaggcgt tccagttgcg aaccaatacg ccagttatca
    61801 ttaaaatcat accagccaga caggcgcgcg ccgggtttat gctcatgatt gaaaacgcgt
    61861 tcagcgtact ctgcctcgag ccagatatta cgtgaccgcc actcaacacc cgcaagccag
    61921 tcgcgaacaa tcccttttcc ttcgctaaat tgtccatcgg cataaccgaa tccagcaaaa
    61981 ccgcgccagt tatccttcag cggtggtgaa taaacgatgg tggttaagtc gacatcatgt
    62041 ttaccactat ccgggccttc ggcatcaatt cctgttgagc cagcgatacg aagctctgca
    62101 agattatgta catcaaccgc acgttttaat cgtacaacgc cgggatcttg cggttcacgt
    62161 tcgacaacat cgtgcgttaa gacagctgcc tgctgccatt cttgtaacgt taatgctgtc
    62221 caggcttgtt caacctccag attaatatta cgtggctcga tcacttctgc tttttttaat
    62281 tcattttctg ctgcacgagg ccaaccgcgg gcttgtaaca cactcgcgta atcaatgcgc
    62341 agtccctgat ttcctggtgc gttataagca agctctctgg ctgtcatttc agcctgagga
    62401 agatcattac tatattttgc tacggttgag agaaacgaat gcccctgtaa ccaggtatca
    62461 ttcgggatgc tcgtaggcgt gcccattaac cgaaggaaag gcggcgaagt attaatggta
    62521 tgttgggtga cagttagcgc gcccggataa ttttcactct ccaggtggct gtaaaagaga
    62581 tccgcaagtt cttcatcgga taaatccggg gcaatggtct ccttgtgata aaagagctcg
    62641 gtcattattg actgtgcttt tttcggctga tgatctttga gataagccga tgcaacccaa
    62701 tattgccccc agggcggaat aatttgcccc gtctttttta atcgctgata gtgagaaata
    62761 acgtctttat aacgatcgcg agttaataac gcgccaagat gatcaacctg aatacgctgg
    62821 tactgggcag tgcggtctgg gttatcgtgc cacagaattt ctaatgcagc gtattgggcg
    62881 agggcgcgat cggcaatggc ataacgttca ctttcactgc gcgtaggcat aaacgacagt
    62941 ctgaccagtt cggcatgaat atcagcgcga atatctggcg ttaaattggc atcgtcaatc
    63001 gcggcagcaa gttgattatt acgtaatgcc tgcacgtatt ctgtgggata ttgttgcgta
    63061 gatgcatttt caggtaatga ctctgtcatc gcccgtaatt catcctgatg acgccccgcc
    63121 agtttataga tataggcttc tgcgagtaaa ttggctttgt ccggtgctcc agagttaagc
    63181 tgcttaagtt taaccagcgc agtatcatag tgaccagcat ctgccagggt taaaatttgt
    63241 ccccgttgat aatccttatt ttgcggctcc agagagagcg ccttttgcca cagtgtaagc
    63301 gagttttgcc attgttgcag gttacgataa gcgacggcga cagctgcata accacgcgct
    63361 ggtaattgct gatgacggta gcggttgtaa acggtaataa cctgtttatc ttgcccggcc
    63421 cataaggcaa tctgtaacca gtcagcaatt tggttattgc tgagtgctga ttttagtgca
    63481 aaccatgaca aagctggctg agtattaccc ttgcgagctt caataatcaa tgcatcatag
    63541 gcgttattaa cagcactctt cgccgcggga ctcgctgcta aaaatgcggc agtaagaagt
    63601 ttcaaagccc atttggtttt cgggcacctt tttctgctac ttgaatacat cctgtattac
    63661 tccatgtatt gccaaaatct ctctctgtat ctaattacag gtaactgaaa agaaagatat
    63721 ttttgcacct cataatccgt tattaaacgc ggaagagaga cgtgaattgt tgatgatgag
    63781 aagaagaaat gatgagcaga gtgtccatat aaaatccttt tctcgcccga aaatccattc
    63841 caatgatgag gatcttcagg aatacggcat aaatcccaat gcctttttca aaataaatta
    63901 ggattaaaat aattaaatca gtaaattccg atgcatgatt tcggattttt cgaaagtcct
    63961 gatgaaaggc tgcgctacgg cactcacgga tttaattgtt attcctaatg tatctatgaa
    64021 ttaatgtttt ataaggattt tctataacca tttataagta ttttcaagcc tggcttgttg
    64081 caaacaatgt ataaagcact taggcaataa taattacatt cagcaactat catcatcggt
    64141 attgtttgtg ggcggaattt catattgaca acagtacagt tcttatatct attaataata
    64201 gaaagggatc tacaacctac agattggtgt agctttatgg aaaaagacta tttgagaatt
    64261 agtagtactg tattagtgag cttattgttt gggcttgctt tggttttggt gaatagttgg
    64321 tttaatcagc caggcgttga ggaagttgtt ccacgatcaa cctatctgat ggtaatgatt
    64381 gctttatttt ttatcgatac tgttgcattt atttttatgc agttgtattt catttatgac
    64441 cgtaggcaat tttcaaactg tgtacttagt ttggcttttc tgagttgttt gatttacttt
    64501 gttataaccg tcattatcat tcagcaaatt attgaggagc gtttgacaag cagtgttgtc
    64561 caaaatgaca ttgcaatcta ttatttgttt cgtcagatga gtttgtgcat attaatattt
    64621 ctggcattgg tgaataaagt tagtgaaaac acaaaacagc gcaatttatt ttccaaaaaa
    64681 atgactttgt gcataagttt gttttttgtt tttggggggc cgatagttgc tcacatactt
    64741 tctagtcatt atgagagcta caatttacac attgccgagt taaccaatga aaatggtcag
    64801 gtggtttgga aagcctcata tgttaccata atgattttca tgtggttaac cttgctttcg
    64861 gttaatctat actttaatgg tttacgctat gatatctgga atggagtgac ggtgattgct
    64921 ttttgtgccg tactgtacaa tatctctctg ttatttatga gcaggtatag cgtgtccact
    64981 tggtatatta gtcgcactat tgaagtagtc agtaagttaa ccgttatggt aatatttatg
    65041 tgccatatat tcagtgcgct acgagtaaca aagaacattg cacatcgcga tcccttaacc
    65101 aatatattta acagaaatta tttttttaat gaactgacag ttcaatcagc atcagcccaa
    65161 aaaacgcctt attgcgtcat gattatggat atcgaccact tcaaaaaagt caacgacacc
    65221 agggggcatc cggttggcga tcaggtgata aaaacagtgg tgaatatcat tgggaaaagc
    65281 atacgaccag atgacctttt agcgcgcgtc ggcggcgaag agtttggcgt cttgctgacg
    65341 gacatcgata ctgaacgtgc gaaagcttta gcggaaagga ttcgggaaaa tgttgagcgt
    65401 ttaactggcg ataatcctga atacgctata ccacaaaaag tgacgattag tattggcgct
    65461 gttgtgactc aggaaaatgc gttaaaccca aatgagatct atcgactggc tgataacgca
    65521 ctttacgagg cgaaagagac cgggcgtaat aaggtggttg tgagggatgt ggtgaatttt
    65581 tgtgagtcac cataaagcgg cat
//
LOCUS       DACAOP010000017        57315 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.017, whole genome shotgun sequence.
ACCESSION   DACAOP010000017 DACAOP010000000
VERSION     DACAOP010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 57315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57315
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.017"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            112..765
                     /gene="nfsB"
                     /locus_tag="IT892_001209"
     CDS             112..765
                     /gene="nfsB"
                     /locus_tag="IT892_001209"
                     /EC_number="1.5.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NAD(P)H nitroreductase"
                     /protein_id="HAP3134447.1"
                     /translation="MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQE
                     DADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD
                     AVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV"
     gene            873..2120
                     /locus_tag="IT892_001210"
     CDS             873..2120
                     /locus_tag="IT892_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAP3134448.1"
                     /translation="MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIILHWVV
                     LRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTC
                     AQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRF
                     LDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEY
                     LRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEE
                     FGLRLHQSPTGNDIRSLAGAFKQ"
     gene            complement(2201..3577)
                     /gene="pheP"
                     /locus_tag="IT892_001211"
     CDS             complement(2201..3577)
                     /gene="pheP"
                     /locus_tag="IT892_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="HAP3134449.1"
                     /translation="MKNASTVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLG
                     IGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFL
                     SGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGET
                     EFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVI
                     MFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSN
                     SSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTR
                     VSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRF
                     RAAMRRQGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFM
                     AFKTLRRK"
     gene            complement(3679..6822)
                     /gene="cusA"
                     /locus_tag="IT892_001212"
     CDS             complement(3679..6822)
                     /gene="cusA"
                     /locus_tag="IT892_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter permease
                     subunit CusA"
                     /protein_id="HAP3134450.1"
                     /translation="MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSD
                     VQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTD
                     PYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQ
                     DWFLKYELKTIPDVAEVASVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAG
                     GSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQIGPEMRRGIA
                     ELNGEGEVAGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRA
                     IDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMS
                     LGGIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPAL
                     FISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGK
                     IPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQIN
                     EGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVPEVARVFGKTGKAETATDSAPLEMV
                     ETTIQLKPQEQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIG
                     IKVSGTVLADIDAMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTV
                     ADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITL
                     ADVADIKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSV
                     AFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWL
                     LWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAVPSLNNPQTFSEQKLDEA
                     LYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFI
                     IPAAYKLMWLHRHRVRK"
     gene            complement(6834..8057)
                     /gene="cusB"
                     /locus_tag="IT892_001213"
     CDS             complement(6834..8057)
                     /gene="cusB"
                     /locus_tag="IT892_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     adaptor subunit CusB"
                     /protein_id="HAP3134451.1"
                     /translation="MKKIALIIGSMIAGGIISAAGFTWVAKAEPPAEKTSTAERKILF
                     WYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRG
                     PLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVE
                     AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVI
                     TAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTL
                     TIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQALID
                     TGSEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
                     GALERMRSESATHAH"
     gene            complement(8073..8405)
                     /gene="cusF"
                     /locus_tag="IT892_001214"
     CDS             complement(8073..8405)
                     /gene="cusF"
                     /locus_tag="IT892_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     metallochaperone CusF"
                     /protein_id="HAP3134452.1"
                     /translation="MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVV
                     KGIDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSL
                     LQDIKVSQ"
     gene            complement(8563..9936)
                     /gene="cusC"
                     /locus_tag="IT892_001215"
     CDS             complement(8563..9936)
                     /gene="cusC"
                     /locus_tag="IT892_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter outer
                     membrane channel CusC"
                     /protein_id="HAP3134453.1"
                     /translation="MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVN
                     AADNYQNAGWRTFFVDNQVKTLISEALVNNRDLRMATLKVQEARAQYRLTDADRYPQL
                     NGEGSGSWSGNLKGNTATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRA
                     VHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQAR
                     GVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQI
                     LLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNF
                     IPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQIS
                     AQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTLLDLNYARQVNEISL
                     YTALGGG"
     gene            10093..10776
                     /gene="cusR"
                     /locus_tag="IT892_001216"
     CDS             10093..10776
                     /gene="cusR"
                     /locus_tag="IT892_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper response regulator transcription factor
                     CusR"
                     /protein_id="HAP3134454.1"
                     /translation="MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGD
                     YDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKP
                     FAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
                     FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVG
                     YMLEVPDGQ"
     gene            10766..12208
                     /gene="cusS"
                     /locus_tag="IT892_001217"
     CDS             10766..12208
                     /gene="cusS"
                     /locus_tag="IT892_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) sensor histidine kinase CusS"
                     /protein_id="HAP3134455.1"
                     /translation="MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFA
                     EQDINDLKEISATLERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSQGKTVYHSP
                     GAPDIREFTRDAIPDKDAQGGEVYLLSGPTMMMPGHGHGHMEHSNWRMINLPVGPLVD
                     GKPIYTLYIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSR
                     QIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTP
                     ITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKK
                     MLNLADEVGKVFDFFEALAEDRGVELRFVGDKCQVAGDPLMLRRALSNLLSNALRYTP
                     TGETIVVRCQTVDHLVQVIVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLA
                     IVKSIVVAHKGTVAVTSDARGTRFVITLPA"
     gene            12358..14595
                     /gene="nrfB"
                     /locus_tag="IT892_001218"
     CDS             12358..14595
                     /gene="nrfB"
                     /locus_tag="IT892_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage adsorption protein NrfB"
                     /protein_id="HAP3134456.1"
                     /translation="MDWLLDVFATWLYGLKVIAITLAVIMFISGLDDFFIDVVYWVRR
                     IKRKLSVYRRYPRMSYRELYKPDEKPLAIMVPAWNETGVIGNMAELAATTLDYENYYI
                     FVGTYPNDPDTQRDVDEVCARFPNVHKVVCARPGPTSKADCLNNVLDAITQFERSANF
                     AFAGFILHDAEDVISPMELRLFNYLVERKDLIQIPVYPFEREWTHFTSMTYIDEFSEL
                     HGKDVPVREALAGQVPSAGVGTCFSRRAVTALLADGDGIAFDVQSLTEDYDIGFRLKE
                     KGMTEIFVRFPVVDEAKEREQRKFLQHARTSNMICVREYFPDTFSTAVRQKSRWIIGI
                     VFQGFKTHKWTSSLTLNYFLWRDRKGAISNFVSFLAMLVMIQLLLLLAYESLWPDAWH
                     FLSIFSGSAWLMTLLWLNFGLMVNRIVQRVIFVTGYYGLTQGLLSVLRLFWGNLINFM
                     ANWRVLKQVLQHGDPRRVAWDKTTHDFPSVTGDTRSLRPLGQILLENQVITEEQLDTA
                     LRNRVEGLRLGGSMLMQGLISAEQLAQALAEQNGVAWESIDAWQIPSSLIAEMPASVA
                     LHYAVLPLRLENDELIVGSEDGIDPVSLAALTRKVGRKVRYVIVLRGQIVTGLRHWYA
                     RRRGHDPRAMLYNAVQHQWLTEQQAGEIWRQYVPHQFLFAEILTTLGHINRSAINVLL
                     LRHERSSLPLGKFLVTEGVISQETLDRVLTIQRELQVSMQSLLLKAGLNTEQVAQLES
                     ENEGE"
     gene            14582..17554
                     /gene="nfrA"
                     /locus_tag="IT892_001219"
     CDS             14582..17554
                     /gene="nfrA"
                     /locus_tag="IT892_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage adsorption protein NfrA"
                     /protein_id="HAP3134457.1"
                     /translation="MKENNLNRVIGWSGLLLTSLLSTSALADNIGTSAEELGLSDYRH
                     FVIYPRLDKALKAQKNNDEATAIREFEYIHQQVPDNIPLTLYLAEAYRHFGHDDRARL
                     LLEDQLKRHPGDARLERSLAAIPVEVKSVTTVEELLAQQKACDAAPTLRCRSEVGQNA
                     LRLAQLPVARAQLNDATFAASPEGKTLRTDLLQRAIYLKQWSQADTLYNEARQQNTLS
                     AAERRQWFDVLLAGQLDDRILALQSQGIFTDPQSYITYATALAYRGEKARLQHYLIEN
                     KPLFTTDAQEKSWLYLLSKYSANPVQALANYTVQFADNRQYVVGATLPVLLKEGQYDA
                     AQKLLATLPANEMLEERYAVSVATRNKAEALRLARLLYQQEPANLTRLDQLTWQLMQN
                     EQSREAADLLLQRYPFQGDARVSQTLMARLASLLESHPYLATPAKVAILSKPLPLAEQ
                     RQWQSQLPGIADNCPAIVRLLGDMSPSYDAAAWNRLAKCYRDTLPGVALYAWLQAEQR
                     QPSAWQHRAVAYQAYQVEDYATALAAWQKISLHDMSNEDLLAAANTAQTAGNGAARDR
                     WLQQAEKRGLGSNALYWWLHAQRYIPGQPELALNDLTRSINIAPSANAYVARATIYRQ
                     RHNVPAAVSDLRAALELEPNNSNTQAALGYALWDSGDIAQSREMLEPAHKGLPDDPAL
                     IRQLAYVNQRLDDMPATQHYARLVIDDIDNQALITPLTPEQNQQRFNFRRLHEEVGRR
                     WTFSFDSSIGLRSGAMSTANNNVGGAAPGKSYRSYGQLEAEYRIGRNMLLEGDLLSVY
                     SRVFADTGENGVMMPVKNPMSGTGLRWKPLRDQIFFIAVEQQLPLNGQNGASDTMLRA
                     SASFFNGGKYSDEWHPNGSGWFAQNLYLDAAQYIRQDIQAWTADYRVSWHQKVANGQT
                     IEPYAHVQDNGYRDKGTQGAQLGGVGVRWNIWTGETHYDAWPHKVSLGVEYQHTFKAI
                     NQRNGERNNAFLTIGVHW"
     gene            17555..18445
                     /locus_tag="IT892_001220"
     CDS             17555..18445
                     /locus_tag="IT892_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4434 family protein"
                     /protein_id="HAP3134458.1"
                     /translation="MRKFIFVLLTLLLVSPFSFAMKGIIWQPQNRDSQVTDTQWQGLM
                     SQLRLQGFDTLVLQWTRYGDAFTQPEQRTLLFKRAAAAQQAGLKLIVGLNADPEFFMH
                     QKQSSAALESYLNRLLAADLQQARLWSAAPGITPDGWYISAEIDDLNWRSEAARQPLL
                     TWLNNAQRLISDVSAKPVYISSFFAGNMSPDGYRQLLEHVKATGVNVWVQDGSGVDKL
                     TAEQRERYLQASADCQSPAPASGVVYELFVAGKGKTFTAKPKPDAEIASLLAKRSSCG
                     KDTLYFSLRYLPVAHGILEY"
     gene            18628..19389
                     /locus_tag="IT892_001221"
     CDS             18628..19389
                     /locus_tag="IT892_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP3134459.1"
                     /translation="MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNV
                     IELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAA
                     NHSKQQPSRPCEAELTRALLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
                     HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQ
                     LCGYSSTSYFISVFKAFYGLTPLNYLAKQRQKVMW"
     gene            complement(19435..19511)
                     /locus_tag="IT892_001222"
     tRNA            complement(19435..19511)
                     /locus_tag="IT892_001222"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19475..19477),aa:Arg,seq:tct)
     gene            19754..20386
                     /locus_tag="IT892_001223"
     CDS             19754..20386
                     /locus_tag="IT892_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbriae biosynthesis transcriptional regulator
                     FimZ"
                     /protein_id="HAP3134460.1"
                     /translation="MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDY
                     LRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANG
                     FVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRY
                     LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI"
     gene            complement(20389..20904)
                     /gene="sfmF"
                     /locus_tag="IT892_001224"
     CDS             complement(20389..20904)
                     /gene="sfmF"
                     /locus_tag="IT892_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria assembly protein"
                     /protein_id="HAP3134461.1"
                     /translation="MRRVLFSCFCGLLWSSSGWAVDPLGTININLHGNVVDFSCTVNT
                     ADIDKTVDLGRWPTTQLLNAGDTTALVPFSLRLEGCPPGSVAILFTGTPASDTNLLAL
                     DDPAMAQTVAIELRNSDRSRLALGEASPTEEVDANGNVTLNFFANYRALASGVRPGVA
                     KADAIFMINYN"
     gene            complement(20915..21955)
                     /gene="fimH"
                     /locus_tag="IT892_001225"
     CDS             complement(20915..21955)
                     /gene="fimH"
                     /locus_tag="IT892_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001350487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrin D-mannose specific adhesin FimH"
                     /protein_id="HAP3134462.1"
                     /translation="MHTSWLIKEIINKIICRLLLAMACLCLANISWATVCANSTGVAE
                     DEHYDLSNIFNSTNNQPGQIVVLPEKSGWVGVSAICPPGTLVNYTYRSYVTNFIVQET
                     IDNYKYMQLHDYLLGAMSLVDSVMDIQFPPQNYIRMGTDPNVSQNLPFGVMDSRLIFR
                     LKVIRPFINMVEIPRQVMFTVYVTSTPYDPLVTPVYTISFGGRVEVPQNCELNAGQIV
                     EFDFGDIGASLFSAAGPGNRPAGVMPQTKSIAVKCTNVAAQAYLTMRLEASAVSGQAM
                     VSDNQDLGFIVADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPTEGP
                     FSALGYLRVDYQ"
     gene            complement(21934..24537)
                     /locus_tag="IT892_001226"
     CDS             complement(21934..24537)
                     /locus_tag="IT892_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HAP3134463.1"
                     /translation="MKIPTTTDIPQRYTWCLAGICYSSLAILPSFLSYAESYFNPAFL
                     LENGTSVADLSRFERGNHQPAGVYRVDLWRNDEFIGSQDIVFESTTENTGDKSGGLMP
                     CFNQVLLERIGLNSSAFPELAQQQNNKCINLLKAVPDATINFDFAAMRLNITIPQIAL
                     LSSAHGYIPPEEWDEGIPALLLNYNFTGNRGNGNDSYFFSELSGINIGPWRLRNNGSW
                     NYFRGNGYHSEQWNNIGTWVQRAIIPLKSELVMGDGNTGSDIFDGVGFRGVRLYSSDN
                     MYPDSQQGFAPTVRGIARTAAQLTIRQNGFIIYQSYVSPGAFEITDLHPTSSNGDLDV
                     TIDERDGNQQNYTIPYSTVPILQREGRFKFDLTAGDFRSGNSQQSSPFFFQGTALGGL
                     PQEFTAYGGTQLSANYTAFLLGLGRNLGNWGAVSLDVTHARSQLADASRHEGDSIRFL
                     YAKSMNTFGTNFQLMGYRYSTQGFYTLDDVAYRRMEGYEYDYDGEHRDEPIIVNYHNL
                     RFSRKDRLQLNVSQSLNDFGSLYISGTHQKYWNTSDSDTWYQVGYTSSWVGISYSLSF
                     SWNESVGIPDNERIVGLNVSVPFNVLTKRRYTRENALDRAYASFNANRNSNGQNSWLA
                     GVGGTLLEGHNLSYHVSQGDTSNNGYTGSATANWQAAYGTLGGGYNYDRDQHDVNWQL
                     SGGVVGHENGITLSQPLGDTNVLIKAPGAGGVRIENQTGILTDWRGYAVMLYATVYRY
                     NRIALDTNTMGNSIDVEKNISSVVPTQGALVRANFDTRIGVRALITVTQGGKPVPFGS
                     LVRENSTGITSMVGDDGQVYLSGAPLSGELLVQWGDGANSRCIAHYVLPKQSLQQAVT
                     VISAVCTHPGS"
     gene            complement(24568..25260)
                     /gene="fimC"
                     /locus_tag="IT892_001227"
     CDS             complement(24568..25260)
                     /gene="fimC"
                     /locus_tag="IT892_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HAP3134464.1"
                     /translation="MMTKIKLLMLIIFYLIISASAHAAGGIALGATRIIYPADAKQTA
                     VWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAAD
                     RESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSR
                     SGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVNSQIPLPSGVQGKLKFQTVNDY
                     GSVTPVREVNLN"
     gene            complement(25480..26022)
                     /gene="fimA"
                     /locus_tag="IT892_001228"
     CDS             complement(25480..26022)
                     /gene="fimA"
                     /locus_tag="IT892_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308619.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein subunit FimA"
                     /protein_id="HAP3134465.1"
                     /translation="MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVN
                     TDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAIND
                     NLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGT
                     GTSASAGQANADATFIMRYE"
     gene            26493..27359
                     /gene="folD"
                     /locus_tag="IT892_001229"
     CDS             26493..27359
                     /gene="folD"
                     /locus_tag="IT892_001229"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HAP3134466.1"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLP
                     AGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPG
                     DWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTL
                     QACVEYHDPQDE"
     gene            27361..27573
                     /gene="ybcJ"
                     /locus_tag="IT892_001230"
     CDS             27361..27573
                     /gene="ybcJ"
                     /locus_tag="IT892_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein YbcJ"
                     /protein_id="HAP3134467.1"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGA
                     VETRKRCKIVAGQTVSFAGHSVQVVA"
     gene            27681..28202
                     /locus_tag="IT892_001231"
     CDS             27681..28202
                     /locus_tag="IT892_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP3134468.1"
                     /translation="MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLS
                     FKFGVAYGNVFGHRGFTHSLVFVFVVPLLCVFIGRRWFRAGLIRCWLFLTVSLLSHSL
                     LDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLP
                     GMLLMGMLWWRRR"
     gene            complement(28238..29623)
                     /gene="cysS"
                     /locus_tag="IT892_001232"
     CDS             complement(28238..29623)
                     /gene="cysS"
                     /locus_tag="IT892_001232"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAP3134469.1"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVAMVDRMIAEMHKDFDA
                     LNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDL
                     DQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAG
                     GEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLG
                     LLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLE
                     DGPQGTTWRRK"
     gene            29797..30291
                     /gene="ppiB"
                     /locus_tag="IT892_001233"
     CDS             29797..30291
                     /gene="ppiB"
                     /locus_tag="IT892_001233"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase B"
                     /protein_id="HAP3134470.1"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     VDNDFLNFSGESLQGWGYCVFAEVVDGMDVVDKIKGVATGRSGMHQDVPKEDVIIESV
                     TVSE"
     gene            30294..31016
                     /gene="lpxH"
                     /locus_tag="IT892_001234"
     CDS             30294..31016
                     /gene="lpxH"
                     /locus_tag="IT892_001234"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HAP3134471.1"
                     /translation="MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFE
                     AWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKV
                     LELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANS
                     KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGA
                     WHTEGSMVKVTADDVELIHFPF"
     gene            31134..31643
                     /gene="purE"
                     /locus_tag="IT892_001235"
     CDS             31134..31643
                     /gene="purE"
                     /locus_tag="IT892_001235"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAP3134472.1"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSA
                     HRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVL
                     ENPDPRGAA"
     gene            31640..32707
                     /gene="purK"
                     /locus_tag="IT892_001236"
     CDS             31640..32707
                     /gene="purK"
                     /locus_tag="IT892_001236"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAP3134473.1"
                     /translation="MKQVCVLGNGQLGRMLRQAGVPLGIAVWPVGLDAEPAAVPFQQS
                     VITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAE
                     RSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRANETEQLPAECYGECIVEQGINFSG
                     EVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELG
                     YVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVV
                     NNPSVMINLIGSDVNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEA
                     LIPLLPPEYASGVIWAQSKFG"
     gene            complement(32902..33795)
                     /locus_tag="IT892_001237"
     CDS             complement(32902..33795)
                     /locus_tag="IT892_001237"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAP3134474.1"
                     /translation="MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVT
                     TVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
                     RKILDSEAIELLLKEGHVVICSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGL
                     VILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAW
                     IGALSRIEETLAGEAGTCISL"
     gene            complement(33792..34607)
                     /locus_tag="IT892_001238"
     CDS             complement(33792..34607)
                     /locus_tag="IT892_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HAP3134475.1"
                     /translation="MTIIHPLLASSSAPNYRQSWRLAGVWRRAINLMTESGELLTLHR
                     QGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPP
                     AHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLG
                     KGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVSYLRYAAQ
                     GYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP"
     gene            complement(34618..35877)
                     /locus_tag="IT892_001239"
     CDS             complement(34618..35877)
                     /locus_tag="IT892_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009029994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HAP3134476.1"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLH
                     AGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLS
                     AALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFT
                     APVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAAR
                     AVSEEMAEIYLERNMQLQIPSWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGIG"
     gene            complement(35887..37554)
                     /locus_tag="IT892_001240"
     CDS             complement(35887..37554)
                     /locus_tag="IT892_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HAP3134477.1"
                     /translation="MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKA
                     LLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQAL
                     MQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLK
                     TRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGE
                     GITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK
                     ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFIC
                     GLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADSHQIIDLGDDFYTVGRPHPMI
                     DPTLRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARLDNQPLYA
                     IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPAAQQHTPSLL
                     ENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ"
     gene            37871..38920
                     /gene="allD"
                     /locus_tag="IT892_001241"
     CDS             37871..38920
                     /gene="allD"
                     /locus_tag="IT892_001241"
                     /EC_number="1.1.1.154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="HAP3134478.1"
                     /translation="MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQ
                     QNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLA
                     FAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALL
                     PAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSS
                     ELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISD
                     ALYNTSYETKNPFAQ"
     gene            38942..40177
                     /gene="allC"
                     /locus_tag="IT892_001242"
     CDS             38942..40177
                     /gene="allC"
                     /locus_tag="IT892_001242"
                     /EC_number="3.5.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate deiminase"
                     /protein_id="HAP3134479.1"
                     /translation="MITHFRQAIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFK
                     KRMAASGLETRFDEVGNLYGRLNGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWL
                     AIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNS
                     FVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPRPNTVNV
                     VPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKEL
                     VATLTELCEREKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITD
                     LAEGVKTLALMLYQLAWQK"
     gene            40188..40973
                     /gene="allE"
                     /locus_tag="IT892_001243"
     CDS             40188..40973
                     /gene="allE"
                     /locus_tag="IT892_001243"
                     /EC_number="3.5.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-ureidoglycine aminohydrolase"
                     /protein_id="HAP3134480.1"
                     /translation="MGYLNNVTGYREDLLANRAIVKHGNFALLTPDGLVKNIIPGFEN
                     CDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFA
                     LSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGYAPWLVSGNASELERIHYE
                     GMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI"
     gene            complement(41201..42346)
                     /gene="glxK"
                     /locus_tag="IT892_001244"
     CDS             complement(41201..42346)
                     /gene="glxK"
                     /locus_tag="IT892_001244"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 3-kinase"
                     /protein_id="HAP3134481.1"
                     /translation="MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADG
                     GEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGLTGDGKTAVIEMAAASGLMLVAPE
                     KRNPLLASSFGTGELIRHALDNDIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQA
                     LAANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEM
                     VEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAV
                     NLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVH
                     QYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN"
     gene            complement(42368..43669)
                     /locus_tag="IT892_001245"
     CDS             complement(42368..43669)
                     /locus_tag="IT892_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="HAP3134482.1"
                     /translation="MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLL
                     TLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATS
                     LAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFG
                     IADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSH
                     SLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTR
                     YRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVP
                     ALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMA
                     LPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE"
     gene            complement(43726..45087)
                     /gene="allB"
                     /locus_tag="IT892_001246"
     CDS             complement(43726..45087)
                     /gene="allB"
                     /locus_tag="IT892_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase AllB"
                     /protein_id="HAP3134483.1"
                     /translation="MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVM
                     DASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDR
                     ASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
                     FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVF
                     TEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTD
                     QFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGG
                     IAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQ
                     PNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILK
                     HQQ"
     gene            complement(45147..46601)
                     /locus_tag="IT892_001247"
     CDS             complement(45147..46601)
                     /locus_tag="IT892_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative allantoin permease"
                     /protein_id="HAP3134484.1"
                     /translation="MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVP
                     NYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRASYGVR
                     GALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFTLLGLSLPGLI
                     TFLIFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAIWAISLVGIGPIFDYIPSG
                     IQKAENGGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFREQALGQTLGLVVAYILFA
                     VAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILMTTISTNATGNIIPAG
                     YQIAAIAPTKLTYKNGVLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMM
                     AHYFVVMRGQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIHFMEPLS
                     RVSWFVGVIVAFAAYALLKKRTTAEKTGEQKTIG"
     gene            complement(46770..47648)
                     /gene="glxR"
                     /locus_tag="IT892_001248"
     CDS             complement(46770..47648)
                     /gene="glxR"
                     /locus_tag="IT892_001248"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HAP3134485.1"
                     /translation="MKLGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     SVETARQVTEASDIIFIMVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKR
                     FARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADPVRVRQALMGGFASSRILEVHG
                     ERMIKRTFNPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SALVQALELMANHKLA"
     gene            complement(47748..48524)
                     /gene="hyi"
                     /locus_tag="IT892_001249"
     CDS             complement(47748..48524)
                     /gene="hyi"
                     /locus_tag="IT892_001249"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HAP3134486.1"
                     /translation="MLRFSANLSMLFGEYDFLARFEKAAQCGFRGVEFMFPYDYDIEE
                     LKHVLASNKLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKKI
                     NCLVGKTPAGFSSEQIHATLVENLRYAANMLMKEDILLLIEPINHFDIPGFHLTGTRQ
                     ALKLIDDVGCCNLKIQYDIYHMQRMEGELTNTMTQWADKIGHLQIADNPHRGEPGTGE
                     INYDYLFKVIENSDYNGWVGCEYKPQTTTEAGLRWMDPYR"
     gene            complement(48537..50318)
                     /gene="gcl"
                     /locus_tag="IT892_001250"
     CDS             complement(48537..50318)
                     /gene="gcl"
                     /locus_tag="IT892_001250"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HAP3134487.1"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINAD
                     AAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQ
                     EMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSE
                     LDNVMEFEDIADNAADAPTETCFMHYE"
     gene            complement(50408..51223)
                     /gene="allR"
                     /locus_tag="IT892_001251"
     CDS             complement(50408..51223)
                     /gene="allR"
                     /locus_tag="IT892_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor AllR"
                     /protein_id="HAP3134488.1"
                     /translation="MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVS
                     DISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVA
                     GPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCI
                     ASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHP"
     gene            complement(51301..51783)
                     /gene="allA"
                     /locus_tag="IT892_001252"
     CDS             complement(51301..51783)
                     /gene="allA"
                     /locus_tag="IT892_001252"
                     /EC_number="4.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
                     /protein_id="HAP3134489.1"
                     /translation="MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALV
                     EILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDL
                     STLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
                     "
     gene            52013..52939
                     /gene="allS"
                     /locus_tag="IT892_001253"
     CDS             52013..52939
                     /gene="allS"
                     /locus_tag="IT892_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AllS"
                     /protein_id="HAP3134490.1"
                     /translation="MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENT
                     GVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMPSELQQVNDGVERQVNIVINNLL
                     YNPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
                     LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFLPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKF
                     GSGKAVEDIVTLFTQRRPEISGFLEIFGNPRS"
     gene            53008..54102
                     /gene="mnmH"
                     /locus_tag="IT892_001254"
     CDS             53008..54102
                     /gene="mnmH"
                     /locus_tag="IT892_001254"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HAP3134491.1"
                     /translation="MQERHTEQDYRALLIADTPIIDVRAPIEFEHGAMPAAINLPLMN
                     NDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQ
                     RSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQ
                     QQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDES
                     RMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQ
                     EYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYD
                     PMYRYQLEKKAEKVVFRGEWAEVAEWVKAR"
     gene            54218..54583
                     /locus_tag="IT892_001255"
                     /pseudo
     CDS             54218..54583
                     /locus_tag="IT892_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014543172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(55334..55594)
                     /locus_tag="IT892_001256"
     CDS             complement(55334..55594)
                     /locus_tag="IT892_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134492.1"
                     /translation="MLAISSNLSKMIIFIFAIIIIVVLCVITYLYLYKDESLVSKHYI
                     NYMAIPENDGVFTWLPDFFPHVAVDISIYTNVEDDYFFLIFP"
     gene            complement(55575..56282)
                     /locus_tag="IT892_001257"
                     /pseudo
     CDS             complement(55575..56282)
                     /locus_tag="IT892_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308587.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
     gene            complement(56285..56653)
                     /locus_tag="IT892_001258"
     CDS             complement(56285..56653)
                     /locus_tag="IT892_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134493.1"
                     /translation="MKYSSIFSMLSFFILFACNETAVYGSDENIIFMRYVEKLHLDKY
                     SVKNTVKTETMAIQLAEIYVRYRYGERIAEEEKPYLITELPDSWVVEGAKLPYEVAGG
                     VFIIEINKKNGCVLNFLHSK"
     gene            complement(56693..>57315)
                     /locus_tag="IT892_001259"
     CDS             complement(56693..>57315)
                     /locus_tag="IT892_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4329 domain-containing protein"
                     /protein_id="HAP3134494.1"
                     /translation="YDPLQGRYITQDPMGLKGGWNLYQYPLNPLQQIDPMGLLQTWDD
                     ARSGACTGGVCGVLSRIIGPSKFDSTADAALDALKETQNRSLCNDMEYSGIVCKDTNG
                     KYFASKAETDNLRKESYPLKRKCPTGTDRVAAYHTHGADSHGDYVDEFFSSSDKNLVR
                     SKDNNLEAFYLATPDGRFEALNNKGEYIFIRNSVPGLSSVCIPYHD"
BASE COUNT        14426 a        15135 c        13872 g        13882 t
ORIGIN      
        1 agagtgcgtc caggctaaag cggaaatcta tagcgcattt ttctcgctta ccatttctcg
       61 ttgaaccttg taatctgctg gcacgcaaaa ttactttcac atggagtctt tatggatatc
      121 atttctgtcg ccttaaagcg tcattccact aaggcatttg atgccagcaa aaaacttacc
      181 ccggaacagg ccgagcagat caaaacgcta ctgcaataca gcccatccag caccaactcc
      241 cagccgtggc attttattgt tgccagcacg gaagaaggta aagcgcgtgt tgccaaatcc
      301 gctgccggta attacgtgtt caacgagcgt aaaatgcttg atgcctcgca cgtcgtggtg
      361 ttctgtgcaa aaaccgcgat ggacgatgtc tggctgaagc tggttgttga ccaggaagat
      421 gccgatggcc gctttgccac gccggaagcg aaagccgcga acgataaagg tcgcaagttc
      481 ttcgctgata tgcaccgtaa agatctgcat gatgatgcag agtggatggc aaaacaggtt
      541 tatctcaacg tcggtaactt cctgctcggc gtggcggctc tgggtctgga cgcggtaccc
      601 atcgaaggtt ttgacgccgc catcctcgat gcagaatttg gtctgaaaga gaaaggctac
      661 accagtctgg tggttgttcc ggtaggtcat cacagcgttg aagattttaa cgctacgctg
      721 ccgaaatctc gtctgccgca aaacatcacc ttaaccgaag tgtaattctc tcttgccggg
      781 catctgcccg gctatttcct ctcagattct cctgatttgc ataaccctgt ttcagccgtc
      841 atcataggct gctgttgtat aaaggagacg ttatgcagga tttaatatcc caggttgaag
      901 atttagcggg tattgagatc gatcacacca cctcgatggt gatgattttc ggtattattt
      961 ttctgaccgc cgtcgtggtg catattattt tgcattgggt ggtactgcgg accttcgaaa
     1021 aacgtgccat cgccagttca cggctttggt tgcaaatcat tacccagaat aaactcttcc
     1081 accgtttagc ttttaccctg caggggatta tcgtcaatat tcaggcggta ttctggctgc
     1141 aaaaaggcac cgaagcggca gatattctga ctacctgcgc gcagttgtgg atcatgatgt
     1201 atgcgctgct ttcagtcttc tcgttgctgg atgttatttt gaatctggcg cagaaattcc
     1261 cggcagcatc tcagttaccg ctgaaaggga tatttcaggg gattaaactg atcggcgcga
     1321 ttctggtcgg cattttgatg atctcgctgc tgattggtca gtcgccagcg attctgatca
     1381 gcggtcttgg tgcaatggct gccgtgctga tgttggtatt taaagatccg attcttggtc
     1441 tggtggcagg tattcagctt tccgcgaacg atatgctgaa actgggcgac tggctggaga
     1501 tgccgaaata cggcgcggat ggcgcggtga tcgatattgg gttaaccacc gtcaaagtgc
     1561 gtaactggga caataccatt accactattc ccacctggtc tctggtttct gactccttta
     1621 aaaactggag cgggatgtca gcatctggcg ggcgacgtat taagcgcagt atcagtattg
     1681 atgtcaccag tattcgtttt cttgatgaag acgaaatgca acgtctgaat aaagcgcatt
     1741 tgttaaagcc ttatttaacc agccgccatc aggaaattaa tgagtggaat cgccagcaag
     1801 gttctacgga gtcggtatta aatctgcgcc gaatgaccaa tattggaacc tttcgtgcct
     1861 atctgaacga atatctgcgt aaccatccgc ggattcgtaa agatatgacc ttaatggtac
     1921 gccaactggc tccaggtgat aacggtttac cgctcgagat ctacgcgttt actaacaccg
     1981 tggtgtggct ggaatatgaa agcattcagg ctgatatatt cgatcacata tttgcgattg
     2041 tcgaagagtt tggtctgcga cttcatcagt cgccaaccgg caatgatatt cgctctctgg
     2101 cgggtgcatt taagcagtaa ttaaaaaaac cgctctcatc gaatggatga gagcggtttc
     2161 ggatggttga catcgttttg tcggatgtag cgtgaatgcc ttatttccga cgcagcgttt
     2221 taaatgccat aaacaggaat acaatccaca ccggcagcag gatcgctgac aagcgcatat
     2281 catccatcgt gcacatcagc agcaaaatca tgccgaggaa ggcaatgcag agatagttgc
     2341 cgaacggata gagcagcgcc ttaaactgtg tttcacgccc ctgacgtcgc atcgctgcac
     2401 gaaaacgcag atgcgccaga cagatcataa tccagttcaa cagcagcgtt gctaccacca
     2461 gcgccatcag cagaccaaac gctttttgcg gcagcagata gttgattaac accaccagcg
     2521 aagtgatcgc tccggaaagc atcagcgagt taatcggcac accgcgacgg ctgacgcgag
     2581 tcaaaaactt cggcgcatta ccctgcacag aaaggccaaa cagcatgcgg ctgttagagt
     2641 aaaccccgct gttatacact gacagcgatg ctaccagaat gacgaagttc agcgcagaag
     2701 ctaccacgtt gctgtcgaga ttatggaaaa tcatcacaaa cgggctactg ttggatttca
     2761 cttccaccca cggatagagc gccagtaaaa ccaccagtga accgatgtaa aacagcagga
     2821 tgcgatacac cacctgattt accgcttttg gaatgctttt ttccggatcg cgcgcttcag
     2881 cggcagtaat cccaatcagc tccagaccgc cgaaggagaa cataattacc gccagcgaca
     2941 aaatcagccc attccagccg gtggcgaaga aaccaccgta gcgccagagg ttgtcgatac
     3001 tggctttctc gccgccgtga ccagaaaaca gcagccacag gccaaagccg atcataccga
     3061 tgattgccag cactttaatc aacgcaaacc agaactcggt ttcgccatat aagcgcacgt
     3121 tcaccaggtt aacggcgttg atgataataa agaaggcggc agcccaaatc cacgttggaa
     3181 catccgggaa ccagtactgc atatagatgc ccgcagcggt cagctctgcc attcccacca
     3241 gcacgaacat tacccagtag ttccagccag agaggaagcc cgcaaacggt ccccagtatt
     3301 tataggcaaa gtgggcaaat gaaccggata ccggctcctc aaccaccatt tcgccaagct
     3361 ggcgcataat caggaaagcg atgatcccgg cgacgccgta gcccagcaat acagccggac
     3421 ccgccatctg aatcgccggg ccaatgccaa gaaacagacc agtaccaatt gcgccaccca
     3481 acgcaatcag ttgaatatga cggttatgta atccgcgatg aagcgtcggc tcttgattcg
     3541 acgcagtatc ttccgatacg gttgacgcgt ttttcacgcc tttcccctgt gtgtcttttt
     3601 tgttgagggg caccttttaa catttagtgc ccatcgtcgc aagacacaat ccacacggtt
     3661 aaacggggta tcctgctttt atttccgtac ccgatgtcgg tgcagccaca tcagcttata
     3721 cgccgccggg ataataaaca gcgacagcaa aggtgcggtg atcatgccgc caatcatcgg
     3781 cgcggcaatc cggctcatca cctctgaacc agcccccgtt ccccacagaa tcggcagcag
     3841 accggcgata atcaccgcca ccgtcatcgc tttcgggcgc acgcgcagga ccgcgccgtg
     3901 atataacgcc tcatccagct tctgctcgct gaatgtttgt ggattattca acgacggcac
     3961 ggcctctatg gcgtgacgta aatacatcag catcaccacg ccaaattcgg cggcgacccc
     4021 ggcgagggcg ataaagccag tgcccgtcgc cacggaaaga tgaaagccca tccaccacag
     4081 caaccagatg ccgcccacca gcgcaaacgg tacgctgctg ataatcagca acgcttcgcc
     4141 cacccgacgg aacgccagat acaacagcac gaagataatc atcaacgtca tcggcaccat
     4201 gagtttaagc ttatggttgg cgcgctccag tagctcgaac tgcccggaga atgccacgct
     4261 ggtgcccggt tttaactgca ctttttcagc tatcgctttt tgcaaatcgt gaaccaccga
     4321 caccatgtca cgatcgcggg catcgatata aatccagctc gtcgggcgcg cattctcggt
     4381 tttcagcatc gacggtccgg tagagacttt aatgtcggcc acgtctgcca gggtgatttg
     4441 ctgcttcatc ggcgtcagga tcggcagctg gcgcagtgcc tgcggactat cgcgccagct
     4501 ttgcggataa cgcagattaa ttggataacg ggcaatccct tccaccgttt cgccaaccat
     4561 cgccccgccc accgcagaag tcacaaacaa ctgcacatcc gccaccgtca taccgtaacg
     4621 tgcggctttt tcacggttaa tctcaacgtt gatatagcgc ccaccttcca gccgctcggc
     4681 aagcgcagaa gctacgcctg gcaccgttcg cgctacttct tcaatttgct cagccatcgc
     4741 gtcgatatcc gccagcacag tgccggaaac tttaatgccg atggggcttt taatgccggt
     4801 tgagagcata tcgatacggt tacgaattgg cggcacccac agattcgcca gccccggcag
     4861 ccgcacggtg ttatccagtt cctcaatgat tttgtccatc gtcatgcctg gccgccactg
     4921 ctcctgcggc ttaagctgga tggtcgtttc taccatctcc agcggagcag aatcggtggc
     4981 ggtttccgct ttcccggttt tgccaaatac ccgcgccact tcaggtacgc tcataattag
     5041 cttgtcggtt ttttgcagca tactcgccgc ctctgctgcg gaaatccccg gcagcgtcga
     5101 tggcatatac aacaagtcgc cttcattgat ctgcggtaaa aattccccgc caactttatt
     5161 gagcggccag agaaccgtca gcaccgaaag cgccgccacc agcagcgtgg ttttcggcca
     5221 gtgcagtact ttcagcaaca gcggatgata aacacgaatc aaaaagcgat tgagcgggtt
     5281 actgctttcc ggcggaattt tgccacggat ccagtagccc atcaggatcg ggatcactac
     5341 gatcgccagc agcgccgcac ccgccatcgc atacgttttg gtgaacgcca acgggccaaa
     5401 cagacgccct tcctgccctt ccagggtgaa gatcgggata aacgacaacg tgataatcag
     5461 cagactgata aatagcgccg gccccacttc aacagacgca tcggtgatca cctgccagcg
     5521 cgttttatta tccagcgtgg cgtcaggatg ctggtgctgc cactcttcca gccgtttatg
     5581 cgcattctcg atcatgacga tagcagcatc gaccatcgcc ccgacggcaa tcgcaatgcc
     5641 acccaacgac ataatattgg cattcagtcc ctggaagtgc atgacaataa aagcaataca
     5701 caaccccagc ggcaacgaaa taatcgccac cagcgccgag cgcacatgcc agagaaacag
     5761 cgcacagact accgccacca caataaactc ttccagcaac ttgccgctga ggttgtcgat
     5821 ggcgcggtca atgagctggc tgcgatcgta tgttgtaact atctccacgc cttccggcag
     5881 actacttttc agcgtttcca gtttgtcctt cacggcggcg atcacttctc gggcgttttt
     5941 gccggatcgc aggatcacca ccccgcccgc cacttcgcct tcgccgttta gttcggcaat
     6001 gccccggcgc atctccgggc caatctggac cttcgcaaca tcgcgcagat aaacgggcac
     6061 gccattttca ctggctttta aaacgatgtg attaaagtcg tcgagcgttt gcagatagcc
     6121 gctggcgcgc accatatatt ccgcttccgc cagttcgatc gacgaaccgc ccgcttcctg
     6181 gtttgaagca tccagcgcgc tttttacttc ggcgagactg atgccatact gcgccaggcg
     6241 ctggggatcg ataaccacct gatactcttt caccacaccg cccaccgacg ccacttccgc
     6301 aacgtcaggg atggttttca gctcatattt gagaaaccag tcctgtaatg agcgtaaatc
     6361 ggccagatcg tgcttaccgc tgcgatccac cagtgcatat tcatagatcc agccaacacc
     6421 cgtggcatct ggccccagct cggcgctgac tcccgcaggc agcttaccct gtacctggtt
     6481 gaggtactcc agcacccgcg aacgcgccca gtacggatcg gtgccatctt cgaaaatgac
     6541 atacacataa gagtcgccaa actgtgagaa accgcgcaca gtcttcgcgc caggcaccga
     6601 caacatggtg gtggttagcg gataagtcac ctgattttca acgatttgtg gtgcctgacc
     6661 gggatagctg gttttaataa taacctgcac atcggagaga tccggcagcg catccactgg
     6721 cgtattaatg atggtccagg tgccccagat gctcagaaac aacgcgccca tcagcaccaa
     6781 aaaacggttc gccaccgagc gacgaataat ccattcaatc attggttatt ccctcaatgc
     6841 gcatgggtag cactttcaga gcgcatccgc tccagtgcgc cagaaatatt ggcttcggaa
     6901 tcaatcagga acaggccgct ggaaaccacc ttttcacctt ccgccagacc agagcgtaat
     6961 gcggtgacgc cttgcgatgc ctggaaaaca gcaacgcgtt tcggtacaaa gcgcccgtcg
     7021 gcatcaacgg taatcacccg ctgttcgctg ccggtatcaa tcagcgcttg tgacggaatg
     7081 agcagcatcg gttcgctggc ggtgttgagt tgcaaccagg cgttcatgcc cggttttagc
     7141 gcctcgtcgg cgttgtcgac ttccagacgc agctgcagcg tgcgggtcgc ggcatccacg
     7201 ccaggtagca gcgtccattt gcggatggtg agtgttttat ccggtcgcgc cggaacggtg
     7261 agggtaaact gcgaggcatc tttcaccagc caggcgatag actccgggat cgcagcagtg
     7321 acccacaccg ggtccatacc ctgaattttc gctaccacgt tatctttggc gatattcatt
     7381 cccgcgcgca gatcaaacgc ggtgatcacg ccatcaatgg gcgctttgag cgtaaagcga
     7441 gtctggattt tttgcgtggc gatcaggcgg cgaatatccg cctccggcat tcccgccagt
     7501 cgcagccgct caagaatgcc ttcagtctgg gtcgccgtac cgccggtttc gcgcagcagt
     7561 aaatactcac tctgcgcttc cacccagtca ggaatggtca ggtcgagaag cggtgtgccc
     7621 ttttgtactt tatcgcccac ggtaagcgga tacaccttgt cgataaaccc ggcagcgcga
     7681 gcctgcacaa tggcatactg atactcgttg taactgacat tcgccgggaa actctgggca
     7741 aaagtcagcg gtccgcgcgt gacggtagcc gttttcaccc ccagattctg cgtctgagtc
     7801 gggtcaatgc gcacaccaga cgcagaactc tcttcatcgg catatttcgg caccagatcc
     7861 atatccataa acggcgattt acctggttta tcgaaccgcg tattgggata cattgggtcg
     7921 taccagaata agattttacg ttctgcggtc gacgtttttt ctgcaggcgg ttccgccttt
     7981 gcaacccagg taaaacctgc cgcagaaata ataccgcccg cgatcatgct gccgataata
     8041 agcgcgattt ttttcatctc attaaacctg ggttactggc tgactttaat atcctgtaat
     8101 aaagaaaggt tgccctgctg gacaaaatta aacgccactt tgtcgccggt tttaatttca
     8161 ctcattttcg tctgcggggt gatggtaaag cgcatggtca tctccggcca gttcacggca
     8221 gcaatcggat cgtgatggat ggtgattttt ttgctttcca gatcaatacc ctttaccacg
     8281 ccagtggcgc taataacctg tggttgtgct tcgctcatgg tttcatgatg atgttcgtta
     8341 gcctgggcat taaagccaat aacggtaaac agactgaaca ttgcgacttg cagtgctttt
     8401 ttcatttatt ctctcctgga gttaaaagtc atactctaaa taattcgagt tgcaggaagg
     8461 cgacaagcga gtgaatcccc aggagcttac ataagtaagt gactggggtg agcgaacgca
     8521 gacgcagcac atgcaacttg aagtatgacg agtatattgc tgtcaaccgc caccaagtgc
     8581 ggtatacaaa gaaatttcgt taacctgacg ggcataattc agatcaagta aagtttgtcg
     8641 ggttgcaaat aaagaacgct cggcatccag cacttccaga taacttactg cgccgtgctg
     8701 atataatgcc cgcgcccgtt gcaaagtaat ttgcagcgat gccagataac gctgctgggc
     8761 gctaatttga tcgttcaggc tttgacgtaa tgccagcgca tctgccactt ctttaaaggc
     8821 gttctggatt ttctgttcat aattcaccac cgactgctgc tggcgaattt cggcgatatc
     8881 cagattggcc tggttgcgtc cggcattaaa aatggggatc tcaattttgg gtataaaatt
     8941 ccacatcccg ctgctggcgt taaataatga cgatagatcg ctactggcgg tcgatattcc
     9001 gctggtcagg cttatagacg gaaaaaatgc cgcgcgtgca gcgccaatat tggcattagc
     9061 cgccattaac gcgtgttcag cttccataat atccgggcgc tgcaataaga tttgcgacga
     9121 caatcccgcc ggtaatttaa cgctttgcag gctgtcgctg tttactgtct gcgcttgcgg
     9181 cagcttgccg tagcttccca gcaacagttg caatgcatta ttcgcctgcg ccagttcccc
     9241 ctgacgttta gcgatgtcgc tgcgggtact ttctatcacc ccgcgagcct gttccagcgc
     9301 cagaacatta ctgctacctg tcaacagttg tttttcgaca aacgcatatg actgctgata
     9361 attacgcagc gtttcttcgg ctatttgcaa ttgcgcatac gccagttgct gattgaaata
     9421 gctttgcgcg acattagaaa ccagcagaat atgcaccgcg cgctgagctt cctcagtggc
     9481 taaataattt tgtcgctcgg cttcgctcat gttctttaag cgaccgaaaa aatcgaggtc
     9541 aaagctggcg ttaaggccgg tcgaaaactc ccgtgtcgtg gcggtattcc ctttaagatt
     9601 accgctccag ctgccgctgc cctcgccatt gagctgtggg tagcggtcgg catcggtcag
     9661 acgatattgc gcccgtgcct cctgcacttt cagcgtcgcc atgcgcaaat cccgattatt
     9721 caccagcgcc tcgctaatca gcgtcttcac ctgattatca acaaaaaagg tgcgccagcc
     9781 cgcgttctga tagttatctg ctgcgttaac caggccgttc tggctgagtg agaactgctg
     9841 cggcacgggc attgccggac gctgataatc cggtgccagt gaacaaccgg ttagcgcaag
     9901 ggccacacaa aatggcagaa gtttacaagg agacataggc tcataatttc tggtgatttt
     9961 atgccgccaa ctttactcgc caggctctga ttttccggtg acagaaaaat gacaaaattg
    10021 tcattttgcc aataagcgat tgccatctga tcccgctact ctagaattgc ccgggcaaca
    10081 tgcggaggaa atatgaaact gttgattgtc gaagatgaaa agaaaaccgg agaatacttg
    10141 accaaagggt taaccgaagc cggttttgtg gtcgatttgg ccgacaacgg gctgaatggc
    10201 taccatctgg cgatgaccgg tgattatgat ctgataatcc tcgatattat gctgccggac
    10261 gtgaacggct gggatatcgt gcgcatgtta cgctccgcca ataaagggat gccgattctg
    10321 ttgcttaccg cgcttggcac cattgaacat cgcgtcaagg ggctggagtt gggggcagat
    10381 gactacctgg tgaagccatt cgcttttgct gaactgctgg cgcgggtgcg cacattactg
    10441 cggcgcgggg cggcggtgat tatcgaaagt cagtttcagg ttgccgattt gatggtcgat
    10501 ctcgtcagcc gcaaagtcac ccgcagcggc acgcgcatca ctttgaccag taaagagttt
    10561 actctgctgg agttcttcct tcgccatcag ggcgaagtgc tgccccgctc gcttatcgcc
    10621 tcgcaggtat gggacatgaa ttttgacagc gataccaatg ctattgatgt ggcggtgaag
    10681 cggctgcgcg gcaaaatcga caacgacttt gagccgaagc taattcagac cgtgcgcggc
    10741 gtgggttaca tgcttgaggt gccggatggt cagtaagcca tttcagcgcc cgttttcgct
    10801 ggcaacccgc ctgacctttt ttatcagcct ggccaccatc gcggcgtttt tcgcctttgc
    10861 atggatcatg atccactcag taaaagttca ttttgccgag caggatatta atgatttaaa
    10921 agagattagc gccacccttg aacgggtact aaatcaccct gacgaaacgc aagcccgacg
    10981 cttaatgacg ctggaagata tcgtcagtgg ttattccaat gtgttgattt ccctggcaga
    11041 tagtcagggt aaaacggtgt atcactcccc cggtgcgccg gatatccgcg agtttacgcg
    11101 tgacgccata cccgataaag acgctcaggg tggcgaggtg tatctccttt ccggcccgac
    11161 gatgatgatg ccaggccacg gtcacgggca tatggaacac agcaactggc ggatgattaa
    11221 cttgccggtt ggcccgttgg tggacggcaa accgatttat acgctctaca tcgcgctttc
    11281 gatcgatttt catcttcatt acataaatga tttgatgaat aaacttatta tgaccgcatc
    11341 ggtaatcagc atcctgatcg tctttatcgt actgttggcg gtacataaag gtcacgcgcc
    11401 gatccgcagc gtcagccgtc aaatccagaa tattacctcg aaagatctcg acgttcgcct
    11461 cgacccgcag accgtgccca ttgagctgga acagctggta ctgtcgttca accatatgat
    11521 cgagcgtatt gaggatgtct ttacccgcca gtccaatttc tcagcggata tcgctcacga
    11581 aattcgcaca ccaattacga atctcataac gcaaaccgaa atcgccctca gccagtcgcg
    11641 cagccagaag gagctggaag atgtgctcta ctctaatctc gaagaactga cgcgaatggc
    11701 gaaaatggtc agcgatatgc tgtttctcgc tcaggccgat aacaaccagc taatccccga
    11761 aaagaaaatg ctcaacctgg cggatgaagt cggcaaagtg ttcgattttt tcgaggcgtt
    11821 agcggaagat cgcggcgtgg agttgcggtt tgttggcgac aagtgtcagg tcgcgggcga
    11881 tccgctgatg ctgcgtcggg cgctaagcaa cctgctttcg aacgccctgc gttatacgcc
    11941 aaccggagag acaattgtag tgcgctgtca gacggtcgat cacctggtgc aagttatcgt
    12001 cgaaaacccc ggtacgccca ttgcgcccga gcacttaccg cgattgtttg accgtttcta
    12061 tcgcgttgac ccctcccgcc agcgaaaagg tgaaggtagc ggtattggcc tggcgatagt
    12121 gaaatcgatt gttgtcgcgc ataaaggcac ggttgcggta acgtcggatg cgcgggggac
    12181 aaggtttgtt atcacattac ccgcttaatc cttcagcaaa cggcaacttt tataaccagt
    12241 gtaaaaataa cgtgccgcaa tagtcatacc tattaatggt aaaaagctgt cacaattcat
    12301 aaaaaacctt aatatacgcc accctaaaca taaccagcgt taatgtaagg tttttgtgtg
    12361 gactggcttc ttgatgtttt tgctacctgg ctctacggct taaaagtaat cgcgataacg
    12421 ttagcggtca tcatgttcat cagcgggctg gacgattttt ttattgatgt cgtctactgg
    12481 gtacgccgca ttaaacgcaa gttgagtgtt tatcgccgct acccgcgaat gagttaccgc
    12541 gaactgtata aaccagatga aaaaccgtta gcgattatgg ttccggcgtg gaatgaaacg
    12601 ggcgtcatcg gcaatatggc cgagctggcg gcgaccacgc tcgactacga aaactattat
    12661 atctttgttg gcacctaccc caacgacccc gatactcagc gtgatgttga cgaagtgtgc
    12721 gctcgcttcc cgaatgtgca taaggtagtc tgcgcgcgtc ctggccccac cagcaaagcc
    12781 gactgtctga acaacgtgct ggacgccatc acccaatttg agcgtagcgc caatttcgct
    12841 tttgctggtt ttattctgca tgacgccgaa gatgtgattt caccgatgga attgcgtctg
    12901 ttcaactatc tggtcgagcg taaagatctg attcagatcc cggtgtatcc gttcgaacgc
    12961 gaatggacgc acttcaccag catgacttac attgatgagt tttcagagct gcatggcaaa
    13021 gatgttccgg tgcgtgaagc cctcgccgga caagtgccca gcgcaggcgt cggcacctgt
    13081 ttcagccgcc gcgccgtgac cgcactgtta gctgacggtg acggtattgc tttcgacgtg
    13141 cagagtctta ctgaagatta cgacattggc ttccgcctga aagaaaaagg tatgacggaa
    13201 atttttgtcc gttttccggt ggtggacgaa gccaaagaac gcgagcagcg taaattttta
    13261 cagcacgcgc ggacatcaaa catgatctgc gtgcgcgaat atttccccga taccttttcg
    13321 actgcggttc gacaaaaatc ccgctggatc atcggcattg ttttccaagg ctttaaaacc
    13381 cataaatgga cctccagcct gacgctgaac tactttctct ggcgcgaccg caaaggggca
    13441 atcagtaact ttgtcagctt cctcgcgatg ctggtgatga tccagctttt gctgttgctg
    13501 gcgtatgaaa gtttgtggcc cgatgcctgg catttccttt ctattttcag cggcagcgca
    13561 tggttaatga ccctgctgtg gctaaacttt ggtttgatgg ttaaccgcat cgtgcagcgg
    13621 gtgattttcg ttactggcta ctacggcctg acgcaggggc tgctttccgt cctgcgtctt
    13681 ttctggggca acctgattaa cttcatggcc aactggcgcg tgctaaaaca ggtacttcaa
    13741 cacggcgatc cacgtcgcgt ggcgtgggat aaaacaacgc atgacttccc cagcgtgact
    13801 ggcgataccc gctcgttgcg cccgttaggt caaattctgc tggaaaatca ggtcatcact
    13861 gaagaacaac tcgatacagc actgcgtaat cgcgtcgaag gtctacgcct gggcggttca
    13921 atgctgatgc aggggctgat tagcgccgag cagctggcac aggcgctggc agagcaaaac
    13981 ggcgtggcgt gggaatccat cgatgcctgg cagatccctt cctcgctgat tgccgaaatg
    14041 ccggcctccg tggcgctgca ttatgcggta ctgccgctgc gtctggaaaa tgacgagtta
    14101 attgtcggca gtgaagatgg tattgacccg gtttcgctgg cggccctgac gcgtaaagtc
    14161 ggacgcaaag tgcgttacgt cattgttctg cggggacaaa ttgtcacagg gttacgtcac
    14221 tggtatgcac gccgacgcgg tcacgatccg cgggcaatgt tgtacaatgc ggttcagcat
    14281 cagtggctca cggaacagca ggccggtgaa atctggcggc aatatgtgcc gcatcagttc
    14341 ctgttcgccg aaatactgac cacgctcggt catattaatc gttcagcaat taacgtgttg
    14401 ttattgcgcc atgaacgcag ttctctgccg ctcggcaagt ttttggtcac cgaaggcgtt
    14461 atcagccagg aaacgttgga tcgcgtcctg acaattcaac gcgaattaca agtttcgatg
    14521 caatcactat tactcaaagc aggtttaaac acagaacagg ttgcgcaact ggagtccgaa
    14581 aatgaaggag aataacctta atcgcgtcat cggatggtct ggtttactgc tgacgtcttt
    14641 attgagtacc agcgcactcg cagacaatat cggcaccagc gcagaagagc tggggctgag
    14701 cgattatcgc cattttgtta tttatccccg tctcgataaa gcgctgaagg cacagaaaaa
    14761 taacgacgaa gcaaccgcca tccgcgaatt tgaatatata caccagcagg tgccggataa
    14821 tattccgctg actttatacc ttgcggaagc ctatcgccat tttggtcatg atgaccgggc
    14881 gcggctgttg cttgaggatc aactgaaacg tcacccagga gatgcccgac ttgagcgcag
    14941 tctggcggct attccggttg aagtgaaaag cgttacgaca gttgaagaac tgcttgccca
    15001 gcaaaaagcg tgcgatgctg cgccgaccct gcgttgtcgc agtgaagtcg ggcagaatgc
    15061 cctgcggctg gcacagttac ctgtcgccag agcgcaactg aacgatgcga cgtttgctgc
    15121 atcgccggaa ggaaaaacgc tgcgaaccga tctgctgcaa cgggcaatct acctgaaaca
    15181 atggtcccag gcagatacgc tatacaatga agcacgccag cagaacacat taagcgcggc
    15241 agaacgccgt cagtggtttg acgtgcttct tgccgggcag ctggacgatc ggatcctggc
    15301 actgcaatca caggggatct tcaccgatcc tcagtcatat attacttacg cgaccgcgct
    15361 ggcttatcgt ggcgaaaaag cacgcctcca gcattatctc attgaaaata agccactatt
    15421 taccacggac gcacaagaga aaagttggct ctatctgtta tctaaataca gcgctaaccc
    15481 cgttcaggcg ttggcgaatt atacggtaca gtttgccgac aaccgccagt atgttgttgg
    15541 cgcgacgcta ccggtgctgt taaaagaagg tcagtacgac gcagcgcaaa aactgctcgc
    15601 caccctcccc gccaatgaaa tgcttgagga gcgttatgct gtcagcgtgg cgacccgtaa
    15661 caaggctgaa gctctgcgtc tggcacgatt gctgtatcag caagaaccgg caaatcttac
    15721 ccgcctggat caactaacct ggcaactgat gcagaacgag cagtcacgcg aagctgccga
    15781 tttattgctg caacgctatc ctttccaggg cgatgcgcgt gtcagccaga ctttaatggc
    15841 gcgactggcg tctctgctgg aaagtcatcc ttacctggca acgccggcga aggtggcgat
    15901 tttatcgaaa cccttaccgc tggcggagca acgtcagtgg caaagtcagt tgccgggtat
    15961 tgcagataat tgcccggcaa tagttcgctt gctgggcgat atgtcgcctt cctacgatgc
    16021 cgccgcctgg aaccgtctgg caaagtgtta tcgggacacg ctacccggtg tggcgttgta
    16081 tgcatggctt caggccgaac aacgacaacc gagcgcctgg caacatcgtg cggtagccta
    16141 tcaggcgtat caggttgagg actacgccac cgcactggcg gcctggcaga aaatcagtct
    16201 tcacgacatg agcaatgagg atctgcttgc tgctgccaat accgcccaga cggcaggaaa
    16261 tggtgcggct cgcgatcgct ggctacaaca ggcagaaaaa cgtggactgg gaagcaatgc
    16321 cctctactgg tggctgcatg cgcaacgtta cattcctggt cagccggaac tcgcactgaa
    16381 cgatctcacg cgctcaatca atattgcgcc ttctgccaac gcttacgttg cgcgggcgac
    16441 aatttatcgc caacgtcata atgtcccggc cgcggtgagt gatttgcgcg ccgcgctgga
    16501 actggaaccg aataatagca acacccaggc agcgcttggt tacgccttgt gggatagcgg
    16561 tgatatcgca cagtcgcggg aaatgctcga accggcgcat aaagggcttc cggacgatcc
    16621 ggcactgatc cgacaactgg cctacgtgaa ccagcgtctg gatgacatgc ctgcgacgca
    16681 gcactacgcc cggctggtga ttgatgacat tgataatcag gcgctgataa ccccactgac
    16741 cccagaacaa aatcaacaac gcttcaattt ccgccgtttg catgaggagg tcggtcgccg
    16801 ctggacgttc agtttcgatt cttccatcgg cttgcgttcc ggcgcaatga gtaccgctaa
    16861 caataatgtc ggcggcgcag cgccagggaa aagctatcgt agctacggac aactggaagc
    16921 cgagtaccgc atcggacgca atatgctgct ggaaggcgac ctgctctcag tttatagccg
    16981 cgtctttgcc gataccggag aaaacggggt gatgatgccg gtgaaaaatc cgatgtccgg
    17041 caccggtctg cgctggaagc cgctgcgcga tcagatcttt ttcatcgccg tcgaacagca
    17101 gttgccgctg aacggccaaa atggcgcatc cgataccatg ctgcgcgcca gcgcctcatt
    17161 ctttaatggc ggcaaataca gcgacgaatg gcacccgaac ggttcaggct ggtttgccca
    17221 aaacctgtac ctcgatgcgg cgcaatatat ccgccaggat attcaggcgt ggacggcaga
    17281 ttatcgcgtc agctggcatc agaaggtagc taacggacag actattgagc cttacgctca
    17341 cgttcaggac aacggctatc gtgataaagg cactcagggc gcgcagcttg gcggagtcgg
    17401 ggtccgctgg aatatctgga ccggcgagac gcactacgac gcctggccgc acaaagtcag
    17461 tctcggcgtc gagtatcaac atacctttaa ggcgattaat caacgtaacg gagagcgcaa
    17521 caacgcgttt ctcaccattg gagtgcactg gtaaatgcgt aagttcattt tcgtattgct
    17581 gacactgctt ttggtcagcc ctttttcctt tgcgatgaaa ggtattatct ggcaaccaca
    17641 aaaccgagat agtcaggtta ccgataccca gtggcagggg ctgatgagtc agttacgttt
    17701 gcaaggcttc gatacccttg ttttgcaatg gacccgttac ggcgatgcat ttacccagcc
    17761 agaacagcgc acgttattgt ttaagcgggc cgcagctgcg caacaggctg gtctgaagct
    17821 tattgtcggg ctgaacgccg atccggaatt ttttatgcac cagaaacagt cgtccgcagc
    17881 gctggaaagc tatcttaatc gcctgctggc tgccgatctc cagcaagcca gattatggag
    17941 cgccgcgcct ggcataacgc cggatggctg gtacatcagc gcggaaattg acgacctgaa
    18001 ctggcgcagc gaagccgccc gtcagccttt gctaacatgg ttaaacaacg cgcagcggct
    18061 gattagcgat gtttcagcaa aaccggttta tatcagtagt tttttcgccg gaaacatgtc
    18121 gcccgatggc tatcgccaac tgctggaaca cgttaaagca accggcgtta atgtctgggt
    18181 acaggatggc agcggcgtgg ataaactgac cgctgaacag cgtgaacgtt atttacaggc
    18241 cagcgccgat tgccaaagtc ccgcccctgc cagcggcgtt gtttatgaac tttttgtcgc
    18301 cggcaaaggc aaaaccttta cagcgaaacc gaaaccggac gcagaaattg cctcgctgtt
    18361 agcgaaacgt tcctcttgcg gtaaagacac tctctatttc tctctgcgct atttgcccgt
    18421 cgcgcacggc attctcgagt attaaatctc ctccaggtaa gtcgggtacg acctggctta
    18481 cctctttcgc tctcatcaga attccatcaa gattaattgc taaaaagcgt gctaaagaaa
    18541 gaagatcgtt atcggcgaac gggccgatca ctcatgcagg aagcatagat cctttgagcg
    18601 gagtttctga tatctgagga gtgcgaaatg caattgagca gcagtgaacc ttgcgtggtg
    18661 atcctgaccg aaaaagaggt agaggtaagc gtcaataacc atgctacgtt tacccttccg
    18721 aaaaactacc tggccgcctt cgcgtgcaac aataacgtca ttgaactctc aacgttaaat
    18781 cacgtattaa tcacccacat caaccgtaac atcatcaacg attatctgtt gtttttaaat
    18841 aagaacttaa cctgtgtaaa gccctggtcg cggctggcaa ccccggttat cgcttgtcat
    18901 agccgtacac cggaagtgtt ccggctagcc gccaaccaca gcaagcagca acccagcaga
    18961 ccctgcgaag cggagttgac gcgcgcattg ctttttaccg tattgtctaa ctttcttgag
    19021 caatcgcggt ttattgccct actgatgtat atcttacgca gcagcgtccg cgacagcgtc
    19081 tgccgcatta ttcaaagcga tattcagcat tactggaatc tgcgaattgt cgccagttcg
    19141 ctatgtttaa gccccagcct gctcaaaaag aaattaaaaa acgaaaatac cagctatagc
    19201 cagattgtca cagagtgtcg tatgcgttac gccgtacaga tgttattgat ggataacaaa
    19261 aatatcactc aggtggcgca attatgtggc tatagcagca cgtcgtactt tatctctgtt
    19321 tttaaggcgt tttacggcct gacaccgttg aattatctcg ccaaacagcg acaaaaagtg
    19381 atgtggtgaa gggcaaagcg gaaacggata agacgggcat aaatgaggaa gaaatggcgc
    19441 gccctgcagg attcgaacct gcggcccacg acttagaagg tcgttgctct atccaactga
    19501 gctaagggcg cgttgatacc gcaatgcggt gtaatcgcgt gaattatacg gtcaaccctt
    19561 gctgagtcaa tggcttttga tctggttgct gaacaagtga acgaccgcgt ctgattttct
    19621 gatttatttc gctatagcgg caaacaaacg cacaccgctg cgcgtctgaa tcaagaaaac
    19681 ccgtattttc atgtatcaaa gtacaatttc ccgacctaac ggaaaattgt ccgctcctat
    19741 gagactggta actatgaaac caacgtcggt gatcattatg gatactcatc ctatcatcag
    19801 aatgtctatt gaagttctgt tgcaaaaaaa cagtgaattg cagattgtcc tgaaaacgga
    19861 tgattatcgc ataaccatcg attatctccg aacccgtcct gttgatttaa tcattatgga
    19921 tatagacttg cccggaacag acggttttac cttcctgaaa aggatcaaac aaatccagag
    19981 cacagtgaaa gtgttatttt tatcatcgaa atcagaatgc ttttatgctg gcagagcgat
    20041 acaagctggt gctaacggtt ttgtcagtaa atgcaatgat cagaatgata tttttcatgc
    20101 cgttcagatg atcctctccg gatacacgtt ttttcccagc gaaacgctta actatataaa
    20161 aagcaataaa tgtagtacga atagttcaac ggtcactgtg ctatctaatc gtgaagtgac
    20221 catattacgt tatctggtta gcggattatc taataaagaa attgccgata agttattact
    20281 tagcaataaa acagttagtg cgcataaatc taatatttat ggcaagctag gtttgcattc
    20341 aattgtagag cttatcgact acgccaaatt atacgaatta atataatatt aattataatt
    20401 gatcataaat atcgcatccg ctttcgccac acctggccga acaccgctgg ctaacgctcg
    20461 ataattggca aaaaagttta gtgtgacatt gccatttgca tctacttcct cagtcgggct
    20521 cgcctccccc agtgcgagcc gggagcgatc gctattacgt aattcgatgg cgacggtttg
    20581 tgccattgcg ggatcatcca gagccagcag gttggtatcg gatgccggcg ttcccgtaaa
    20641 taaaatcgca actgaacccg gaggacatcc ctccagccgc aggctaaaag ggacgagtgc
    20701 cgtggtatcg ccagcgttca gtagttgtgt cgtaggccat ctgcctaaat ctaccgtctt
    20761 atcaatatcc gctgtgttta cggtacagga gaaatcaaca acgttaccgt gcaaattgat
    20821 attaatcgtt cctaaagggt caactgccca tccactggaa ctccacagta gcccgcagaa
    20881 acagctaaag agtactcttc tcattctccg tacctcattg ataatcgacg cgtaaatacc
    20941 ccagcgcgct aaacggccct tcggtcggtt tttgaccggt aatactgata ggccaggcgc
    21001 gaagtgtgac attggctgcc gcagctgcat ccagacggaa aggaataacg ctattgagat
    21061 cgttaggcgt gatcggcgta tcgttctgat cggcgacaat aaaacctaaa tcctgattgt
    21121 ccgacaccat cgcctgacca gaaacggcac tggcttccag acgcattgtt aaataagcct
    21181 gcgcagcaac attcgtacat ttgaccgcaa tgctcttggt ttgcggcatg acaccagcag
    21241 gtcgattacc cggccctgcc gcactaaata acgatgcgcc gatatcacca aaatcaaatt
    21301 caacaatctg cccggcattt aattcgcagt tttgcggtac ttcaacccgg ccaccaaaac
    21361 taatggtata aacaggtgta accaacggat cgtaaggcgt tgatgtcaca tacacggtaa
    21421 acatcacctg tctggggatc tccaccatgt taataaaggg acgaataacc tttaaacgaa
    21481 atattaaacg agaatccatc accccgaatg gaaggttttg cgaaacgtta ggatctgttc
    21541 ccatccgaat ataattttgc ggggggaact gaatatccat cacactatca accagactca
    21601 tcgcacctaa tagataatca tgtaattgca tatatttata attatcgata gtttcctgaa
    21661 caataaagtt ggtgacataa ctacggtatg tataattcac cagcgtaccg ggtggacaaa
    21721 ttgctgagac acctacccag ccggattttt ccggtaaaac aacaatctgc cctggctggt
    21781 tattggtgct attaaagata tttgagagat catagtgttc atcttctgct acgccagtac
    21841 tatttgcaca aacagtagcc caggatatgt ttgccagaca caaacatgcc atcgccaata
    21901 ataatctgca gattatctta ttgataattt cctttatgag ccaggatgtg tgcaaactgc
    21961 cgaaataaca gtgacggctt gctgtaagct ttgcttcggc aatacatagt gcgcaatgca
    22021 gcgtgagttc gcgccgtctc cccactgaac cagtaattca ccagacaatg gcgcaccact
    22081 taaataaact tgcccgtcat cacccaccat actggttatt ccggtactgt tttcccgtac
    22141 cagtgatcca aacggcaccg gttttccgcc ctgggtaacg gtaatgagcg cccgcacgcc
    22201 tatgcgggta tcaaaattgg cacgaaccaa cgcgccttgc gtcggcacaa cgctgctaat
    22261 atttttttca acatcgatgg aattccccat cgtattggta tcaagcgcga tacggttata
    22321 ccgataaacc gtggcataca gcatcaccgc atagccgcgc cagtcggtta aaatgccagt
    22381 ttgattttca atgcgtacac cgcctgcgcc aggcgcttta atcaaaacat tggtatcccc
    22441 taaaggctgg ctcagcgtta tgccattttc atgcccgacc acaccgccag acagctgcca
    22501 gttaacgtca tgttgatcgc ggtcgtagtt atacccgccc cccagcgtac cgtaagcggc
    22561 ctgccagttt gccgtggcgc tgcccgtgta cccattattc gaggtatcac cctggcttac
    22621 gtgataactc aggttgtggc cttccagtaa ggtcccacct acacctgcca gccagctatt
    22681 ttgcccgttg ctgttacggt tggcgttaaa ggaggcataa gcgcggtcga gcgcattttc
    22741 ccgggtgtag cgacgtttgg tcaaaacatt gaaaggcact gaaacattaa gtccgacaat
    22801 acgttcgtta tcggggatcc ctacagattc attccacgaa aatgagagcg aataactgat
    22861 gccaacccag ctgctggtat accccacctg ataccacgta tctgaatccg aagtattcca
    22921 gtatttttga tgggtaccag aaatataaag cgagccaaag tcattaagtg attgtgaaac
    22981 atttaactgc aaacggtctt tacggctaaa gcgtaaattg tggtaattca cgattatcgg
    23041 ttcatcgcga tgctcaccgt cgtaatcata ttcgtacccc tccattcgac gatacgcaac
    23101 atcatcaagg gtataaaaac cttgtgtcga atagcggtaa cccattaact gaaaattggt
    23161 gccgaaggtg ttcatcgatt tcgcatagag gaagcgaata gaatccccct catgacgact
    23221 ggcgtcggct aactgactgc gcgcatgcgt tacatccagc gacactgcgc cccagttccc
    23281 gagattgcgc cccagcccta ataaaaaggc ggtgtaattg gcagataatt gcgtcccgcc
    23341 gtaggcagta aattcctgtg gtaaaccgcc gagtgccgta ccctgaaaaa agaaaggcga
    23401 tgattgctga ctattaccgc tacgaaaatc gcccgccgtc aggtcaaatt tgaaacgccc
    23461 ttcgcgttgt aaaattggca ctgttgaata cggaattgtg taattctgct gattgccatc
    23521 gcgctcgtcg atggtgacgt ccagatcgcc atttgaagat gtcgggtgca aatctgtaat
    23581 ttcaaaagcg ccgggggaaa catagctttg atagataata aaaccatttt gccgaatcgt
    23641 tagctgggcc gccgtacggg caatcccacg taccgttggg gcaaaccctt gctggctatc
    23701 aggatacata ttatcagaag aataaagccg tacaccacga aatccaacgc catcgaaaat
    23761 atcacttcct gtattgccgt ctcccattac cagttcactt ttcagcggaa taatggcgcg
    23821 ctgtacccag gtgccaatat tattccactg ttctgaatga tatccatttc cgcgaaaata
    23881 gttccaggaa ccattgttgc gtaaacgcca cgggccaata ttaatcccgc tgagctcact
    23941 aaaaaaatag ctatcgttac cattacctct gttaccggtg aaattataat tcaggagtaa
    24001 agcaggaata ccttcatccc actcttcagg cggaatgtaa ccgtgagcgc tactcaacaa
    24061 cgctatctga ggaatagtga tgttcaggcg catcgctgca aaatcaaagt taattgtggc
    24121 atcaggtaca gctttcagta aattgatgca tttattgttt tgctgctggg ctaactcggg
    24181 aaatgcactg ctattaaggc caattcgttc aagaagtacc tggttaaaac agggcattaa
    24241 cccacctgat ttatcacctg tattttctgt tgtcgattca aatacgatat cctgcgaacc
    24301 aatgaactca tcattacgcc agagatccac ccgatacacg cccgcaggtt gatgattacc
    24361 tctctcaaag cgcgataaat cagcaacgga tgtgccattc tctaataaaa atgccgggtt
    24421 gaaataactt tccgcatagc ttaaaaagga gggtaaaatg gcaagagatg aataacaaat
    24481 tccggccaga caccaggtat acctctgcgg aatatccgta gtagtgggta ttttcataat
    24541 tagctctgat attgtcagat gattcggtta gtttaagttc acttctctga ccggagttac
    24601 tgaaccataa tcattaacgg tctgaaattt cagctttccc tgcactcctg agggtaaggg
    24661 aatttgtgaa ttaactctgg gtgcagccat agcattcccc aacttttggc tgcccacttg
    24721 taagttaacc agggtgacat aaaaaggtga tggattatga acattgatat agttaccgga
    24781 tcgcgaaaac ttgagtgtgt ccggcgcttc tgcgggtaat tcttgtaatt gaattggacg
    24841 gagaaataat ttcatgcgcg ataaaatcgc cagttgcaaa acattcctgc cgttcaatgc
    24901 atttttatct accgaaggga tcgtcttaac attcatccag aacagagact cacgatctgc
    24961 tgccagcggt ggaccggtgt aaataatacg caaagtattt tcgcttttgg gttcactaac
    25021 aaacagtggc ggtgtaatga tgaatgactt ttcttttaca ccgctgctgt tttcaatcca
    25081 cgaattgacc agaaagcgct cattggtatg gctatttcta atccataccg cagtctgttt
    25141 agcatcagcg ggataaataa tacgcgtggc acctaatgcg atccctccgg cagcatgggc
    25201 gctggccgaa atgattaaat aaaatataat gagcatcaat aactttattt tagtcatcat
    25261 agttaatacg ccttgtgtat tcctgacggc aaaaataagg aatataaaga aatgattgct
    25321 ttggtttctt acaacacatc attccctttt catttaataa agcggcatga tacaaagtga
    25381 acatgatttc gatttacatt gccaccatac cgcttcagac aaccggtaca ttactttgtt
    25441 ataagacgtg atatataatt caaaacaacg tggttttgat tattcatatc tcataataaa
    25501 agtcgcgtca gcatttgctt gccctgctga tgcacttgta ccggtgcctt tataacgtgc
    25561 agaaaaatga agaacgttgg tcccggggat caagttctgg ttggttgaga agctattccc
    25621 atcaggtttg agaattgcgg atgtattatc aagtatttca ataccgacac ccgttgctgt
    25681 tgttgtattg gtactggatg caatggccaa taaattatca ttgattgcat cagcctgacc
    25741 agaaaatgca acggcagcat tagcggcaac aacaggatcg cagtcgttca actgaatggt
    25801 gaatggaatt aatgcagagg tattaccaac agcattgaaa atatcggtac gatattgacc
    25861 gagtgtgaca acctggtctg ccgagtcagt attcactgaa caggcagcat tcaccagttc
    25921 gccttcaaag tgaattgtac cgccatctac aacggcagca taactacccg tagcggcgaa
    25981 tagtgcggca gccagcgcag acgaaataaa tcttaatttc atatatattc cttcaatctc
    26041 atttatcgac tccacatccg tatataaccg attactttat ttaagacact gatagtagta
    26101 aattcctttt tatcctctaa gaatgtctta attgaaaata tgcactctat tctaaaaaat
    26161 agagagcccc gttagatgaa tacttccgcg caaaatatat tcaacacaaa tatagacctg
    26221 aagcggtaaa ttaccaggct gaaaattctt tttatattgt caggtatttc ttaaattatc
    26281 ttaatcctta gacaaggaaa taaatcagtt ccagatttac aacgccatca tggacgaaaa
    26341 atgaagcttt cagtctcagc gacggtgcgc ctcaccttcg caagaggtcg cttcacgcga
    26401 taaatctgaa acgaaacctg acagcgcgcc ccgcttctga caaaataggc gcatcccctt
    26461 cgatctacgt aacagatgga atcctctctc tgatggcagc aaagattatt gacggtaaaa
    26521 cgattgcgca gcaggtgcgc tctgaagttg ctcaaaaagt tcaggcgcgt attgcagccg
    26581 gactgcgggc accaggactg gccgttgtgc tggtgggtag taaccctgca tcgcaaattt
    26641 atgtcgcaag caaacgcaag gcttgtgaag aagtcgggtt cgtctcccgc tcttatgacc
    26701 tcccggaaac caccagcgaa gcggagctgc tggagcttat cgatacgctg aatgccgaca
    26761 acaccatcga tggcattctg gttcaactgc cgttaccggc gggtattgat aacgtcaaag
    26821 tgctggaacg tattcatccg gacaaagacg tggacggttt ccatccttac aacgtcggtc
    26881 gtctgtgcca gcgcgcgccg cgtctgcgtc cctgcacccc gcgcggtatc gtcacgctgc
    26941 ttgagcgtta caacattgat accttcggcc tcaacgccgt ggtgattggc gcatcgaata
    27001 tcgttggccg cccgatgagc atggaactgc tgctggcagg ttgcaccact acagtgactc
    27061 accgcttcac taaaaatctg cgtcatcacg tagaaaatgc cgatctattg atcgttgccg
    27121 ttggcaagcc aggctttatt cccggtgact ggatcaaaga aggcgcaatt gtgattgatg
    27181 tcggcatcaa ccgtctggaa aatggcaaag ttgtgggcga cgtcgtgttt gaagacgcgg
    27241 ctaaacgcgc ctcatacatt acgcctgttc ccggcggcgt tggcccgatg acggttgcca
    27301 cgctgattga aaacacgcta caggcgtgcg ttgaatatca tgatccacag gatgagtaac
    27361 atggcgacat tttctttagg taaacatccg cacgttgagc tgtgcgactt gctgaaactg
    27421 gaaggctgga gcgaaagcgg cgcgcaggcg aaaatcgcga ttgccgaagg ccaggtgaaa
    27481 gtcgacggtg cggttgaaac gcgcaaacgc tgcaaaatcg tcgccggtca gacagtgagt
    27541 tttgcaggtc acagcgtaca ggttgttgcc tgatcccttt cccggcctgt atcaacaggc
    27601 cggttctctt ttcagacttt tgccctctac gccccgttca tccatgctga tagcatcgac
    27661 attttgccga agcgaccatc atgccaaccg ttattacgca cgccgccgtt cccctatgca
    27721 ttggtttagg gttgggttcg aaagtcatcc ctccgcgtct gttatttgcc ggaatcatcc
    27781 tggcgatgct gcccgacgcc gacgtattgt cgtttaaatt tggcgttgct tacggcaatg
    27841 tttttggtca tcgcgggttt acccattcgc tggtgtttgt gtttgttgtc ccgctgttat
    27901 gtgtgtttat tggacgccga tggttcaggg ctgggctgat tcgctgctgg ctgtttttaa
    27961 ccgtctcgtt gctatcgcac agcttgctgg attcggtaac cactggcggt aaaggcgttg
    28021 gctggctgtg gccgtggtca gatgaacgct ttttcgctcc ctggcaggtg ataaaagtcg
    28081 cgccgtttgc attgtctcgt tacaccacgc cgtacgggca tcaggtgatt atttctgaat
    28141 tgatgtgggt gtggttgccg gggatgctac tgatgggaat gttgtggtgg cgcagacgat
    28201 aaccggatgc gaaaactcgc atccggcaat agcgcaatta cttacgacgc caggtggtcc
    28261 cttgcgggcc atcttccagc acgatcccca tctcgttaag acgatcacgc gccgcatccg
    28321 ccgccgccca gtctttcgct ttacgggcat ccagacgctg ttgaattaac gcttcaatct
    28381 cagccacttc gctgtcgtct gcctgcgcgc cgctttgcag gaacgcttcc ggttcttgct
    28441 ccagcaggcc caatacagcg gaaagtttac gcaggtgaga tgccattgca ttcgccgctg
    28501 ccatatcttc tgctttcaga cggtttactt cacgcgccat atcaaacagt acggaatagg
    28561 cttccggggt gttgaaatcg tcgtccatcg cttcaataaa gcgcgcttca aacgcttcgc
    28621 caccggcagg cgcaacggtt ttatctgtgc cgcgcagcgc agtgtagaga cgctccagcg
    28681 ccgcacgcgc ctgcttcagg ttctcttcgc tgtagttcaa ctggctgcga tagtggcccg
    28741 acatcaggaa gtaacgcacg gtttccgcgt cgtagtattt cagcacatcg cgcacggtaa
    28801 agaagttacc cagcgatttg gacatcttct cgcggtcaac catcaccatc cccgagtgca
    28861 tccagtagtt cacatactga ccatcatggg cacaggtgga ctgcgcgatt tcgttttcgt
    28921 ggtgcgggaa catcaggtct gaaccgccgc cgtggatatc aaagtggtta cccagctgct
    28981 tgcagttcat tgccgaacat tcaatgtgcc agccaggacg acccgcgccc cacggagacg
    29041 gccagctcgg ttcgccctct ttcgacatct tccacagaac gaagtccatt gggttgcgtt
    29101 tgtcgtcgac cacgtcaacg cgcgcgcctg cctgcagctg gtcgagatcc tgacgcgaca
    29161 gcacgccata agttggatcg gtcgggacgt cgaacatcac gtcgccgttg tccgccacat
    29221 aagcgtgacc tttggcgatc agttgttcag tgagttcaat aatttctgcg atatggtgcg
    29281 tcgcgcgcgg ctccatatcc gggcgcagaa tgttcaaagc atcaaaatct ttgtgcattt
    29341 cggcgatcat gcgatccacc atcgccacaa agctttcgcc attttcattg gcgcgtttga
    29401 tgattttgtc gtcgatatcg gtaatgttgc gcacatactt cagtttatag ccgaggaaac
    29461 gcagatagcg cgcaaccacg tcaaaagcaa caaaggtacg cccgtgaccg atatgacaga
    29521 gatcgtaaac ggtgattcca cacacgtaca tgccgacttc cccggcgtga ataggcttaa
    29581 attcctcttt ttggcgtgtc agagtattga agatttttag catcgaagat tccgtttaga
    29641 catgtgtggg taattgagtt gcgtataata cccatatttc ccgcgcgaat cagcatacat
    29701 tgcgtgatga tccgatcgtg cggttatgct ataacaccac cctatatatg acccgaactg
    29761 ggttgaagca ccaatcaaac ggaacaggat gcaaaaatgg ttactttcca caccaatcac
    29821 ggcgatattg tcatcaaaac ttttgacgat aaagcacctg aaacagttaa aaacttcctg
    29881 gactactgcc gcgaaggttt ttacaacaac accattttcc accgtgttat caacggcttt
    29941 atgattcagg gcggcggttt tgaaccgggc atgaaacaaa aagccaccaa agaaccgatc
    30001 aaaaacgaag ccaacaacgg cctgaaaaat acccgtggta cgctggcaat ggcacgtact
    30061 caggctccgc actctgcaac tgcacagttc ttcatcaacg tggttgataa cgacttcctg
    30121 aacttctctg gcgaaagcct gcaaggttgg ggctactgcg tgtttgctga agtggttgac
    30181 ggcatggacg tggtagacaa aatcaaaggt gttgcaaccg gtcgtagcgg tatgcaccag
    30241 gacgtgccaa aagaagacgt tatcattgaa agcgtgaccg ttagcgagta atcgtggcga
    30301 cactctttat tgcagatctt catctctgcg tggaagaacc ggcgatcacc gccggttttc
    30361 tgcgtttttt agcgggggaa gcccgcaagg ccgacgcgct gtatattctt ggcgatctgt
    30421 ttgaagcatg gattggcgac gacgatccca acccactcca tcgcaagatg gcggcggcga
    30481 tcaaagcggt gtccgattcc ggcgttccct gttatttcat tcatggcaac cgtgattttc
    30541 tgctcggcaa acgctttgcc cgtgaaagtg gcatgacgtt attgccggaa gaaaaggtgc
    30601 tcgaacttta tggtcgccgg gtgttgatta tgcatggcga cacgctgtgc accgatgacg
    30661 cgggttatca ggcttttcgc gccaaggtcc acaaaccctg gctgcagacg ctattcctcg
    30721 ccctgccgtt gtttgtgcgc aaacgcattg ccgcgcgaat gcgcgcgaac agcaaagaag
    30781 ccaacagcag taaatcgctg gcgatcatgg acgttaacca aaacgcggtg gtcagtgcga
    30841 tggaaaaaca tcaggtgcaa tggctgatcc acgggcatac ccatcgcccg gcggtgcatg
    30901 aacttatcgc caatcagcaa cctgcttttc gcgtggtact gggtgcctgg catacggaag
    30961 gttcaatggt gaaagtcacg gcggatgacg ttgagctgat tcattttccg ttttaaaaaa
    31021 cccgcaactt tgctgatttc acagccacgc aaccgttttc cttgctctct ttccgtgcta
    31081 ttctctgtgc cctctaaagc cgagagttgt gcaccacagg agttttaaga cgcatgtctt
    31141 cccgcaataa tccggcgcgt gtcgccatcg tgatggggtc caaaagcgac tgggctacca
    31201 tgcagttcgc cgccgaaatc ttcgaaatcc tgaatgtccc gcaccacgtt gaagtggttt
    31261 ctgctcaccg cacccccgat aaactgttca gcttcgccga aagcgccgaa gagaacggtt
    31321 atcaggtgat tattgcgggc gcaggcggcg cagcgcatct gccaggcatg attgccgcca
    31381 aaacgctggt gccggtgctg ggcgtgccag tacagagcgc cgcactgagc ggtgtcgata
    31441 gcctctactc catcgtacaa atgccgcgcg gcattccggt gggtacgctg gcgattggta
    31501 aagctggcgc ggcaaacgcg gcgttactgg cagcacaaat tcttgcgact catgataaag
    31561 aactgcacca gcgtctgaat gactggcgca aagcccagac cgacgaagtg ctggaaaacc
    31621 cggacccgcg aggtgcggca tgaaacaggt ttgcgtcctc ggtaacgggc agttaggccg
    31681 tatgctgcgt caggcaggcg taccgttagg cattgctgtc tggccagtcg ggctggacgc
    31741 tgaaccggcg gcggtgcctt ttcaacaaag cgtgattacc gctgagatag aacgctggcc
    31801 ggaaaccgca ttaacccgcg agctggcgcg ccatccggcc tttgtgaacc gcgatgtgtt
    31861 cccgattatt gctgaccgtc tgactcagaa gcagcttttc gataagctcc acctgccgac
    31921 tgcaccgtgg cagttacttg ccgaacgcag cgagtggcct gcggtgtttg atcgtttagg
    31981 tgagctggcg attgttaagc gtcgcactgg tggttatgac ggtcgcggtc aatggcgttt
    32041 acgcgcaaat gaaaccgaac agttaccggc agagtgttac ggcgaatgta ttgtcgagca
    32101 gggcattaac ttctctggtg aagtgtcgct ggttggcgcg cgcggctttg atggcagcac
    32161 cgtgttttat ccgctgacgc ataacctgca tcaggacggt attttgcgca ccagcgtcgc
    32221 ttttccgcag gccaacgcac agcagcaggc gcaagccgaa gagatgctgt cggcgattat
    32281 gcaggagctg ggctatgtgg gcgtgatggc gatggagtgt tttgttaccc cgcaaggtct
    32341 gttgatcaac gaactggcac cgcgtgtgca taacagcggt cactggacac aaaacggtgc
    32401 cagcatcagc cagtttgagc tgcatctgcg ggcgattacc gatctgccgt taccgcaacc
    32461 agtggtgaat aatccgtcgg tgatgatcaa tctgattggt agcgatgtga attatgactg
    32521 gctgaaactg ccgctggtgc atctgcactg gtacgacaaa gaagtccgtc cggggcgtaa
    32581 agtggggcat ctgaatttga ccgacagcga cacatcgcgt ctgactgcga cgctggaagc
    32641 cttaatcccg ctgctgccgc cggaatatgc cagcggcgtg atttgggcgc agagtaagtt
    32701 cggttaactg gtgctctatt cttgccggat gcggcgtaaa cgccttatcc ggcctaccga
    32761 tccggtaccc attgtaggcc tgataagatg cgtcaagcat cgcatcaggc attgtgcacc
    32821 aattgccgga tgcggcaccg gttgtaggcc tgataagacg cgtcaagcgt cgcatcaggc
    32881 acaaatgtct aatgcctacg actacagcga aatacaggtc cccgcttcgc ccgccagcgt
    32941 ctcttcaatt cgcgataacg ccccaatcca cgcgggttta ccacggcttc tgacataacc
    33001 actcaccgcc gttaccttcg gccccatcga accatcggct ttggcaaatg gcgctaactc
    33061 atccggtgtg gcatggcgaa tggcacgttg ctgcggcgtt ccccagtttt catataccgc
    33121 atcagcatcg gtgaggatca ccagtccatc tgcattaatc tgctcggcga gcaacgcagc
    33181 ggcgagatct ttatcaatca ctgcttcact ccctgctccg tcatccgtca caggcacacc
    33241 gccgccgcca ctgcaaatca ccacatgccc ctctttgagc aacaactcga tggcttcgct
    33301 gtcgagaatt ttacgcggtt gcggagacgc caccacccgg cgcaaatatt taccatcacg
    33361 tttcatctgc cagccgtaag ccgcttccag tgcctcttgt tcttctggct gataaaccgg
    33421 accaataaat ttctctggct gcaaaaacgc cggatcatca ggcgaaacct caatgcgcgt
    33481 cagcaccgtc gtcacgggcg gcatctgcgg ctgtgcgctc aaactctgcg ccagcatata
    33541 gccaatcatc ccctggcttt ccgcaaccag cacatccagc ggatacggtt ctacctcttt
    33601 ccacgccaga ttctgcaatg ccagcagccc cacctgcggc ccgttgccgt gaacaatcgc
    33661 caaccgataa gaacgggcca ggcgtgccag cgcgggtaca gcactggcga tattgcgata
    33721 ttgattttct gccgtcagcg cctcaccgcg ctggagtaag gcgttgcccc caagagccac
    33781 aaccagtgtt ttcatggttt tccttgtaat aattgttggc caagccagaa ccccagcagc
    33841 gtatctgccc ctgacgtatg ccccagcgcc agcagcgaat caatcgcaac agcggtacgt
    33901 ttcgggcaac tcagagcatg aacaaagtgc aggagtggcg aggcgaaata tccttgcgcg
    33961 gcataacgta aataactgac gctcaccgct gtggtaacga gttgcagatt gtcggaacag
    34021 gcaaaaaacg gacgaccgga gcgcgcatct aaagcgccat aataccaggc cgccagcagc
    34081 attccgctca gcgtgtcatc atgactcggc gttaatccgg ggcctttacc cagccagtgc
    34141 cgccagtcgg tcttaacgcc attgagcgcg gcctgaaaac agtgacgaaa ctggcgtaac
    34201 tcagcaggca gcggatcgct tgccgccaac gccagtggcc cgaaaagccc ggtttcctcc
    34261 gcgcgttgca tccatgcagc tgcaagtggt tgaggatgcg caggcggcgt aatacgcagc
    34321 aaacaataac gctgtggctg tttaaccgtg aaacgcccga ggcgaatccc ttgagccaca
    34381 acctgtggtc gttcattgcc gcataatcca ccgcataacg catcgaattg cgcacggcga
    34441 agcacccatc ctccggggcc gaaaccacta ccctgacgat gcaacgttaa cagttcgccg
    34501 ctttccgtca tcaggttaat cgcccgccgc cacactcccg ctaaccgcca ggactggcga
    34561 taattcggtg cgctactact ggcaagcaga ggatggatga tcgtcattgc gcgttcctca
    34621 accaataccc atgctttcag ccagtgcttc cagcgcctgt tcaaagcacg ccagcggtgc
    34681 ccgcacggtg cctgcgccaa tctgcccgat ccccgcctct ttatgggcga taccggtatt
    34741 gatgagtggc gtaatgccgg tttctaccac gcgacgaatg tccagcccca ggcacgcgcc
    34801 ctgaaaatcc cagcttggga tctgcaactg catattgcgt tcaaggtaaa tttccgccat
    34861 ctcttcagat accgctcttg ccgcttccat gccacccgca ccgacaaagc gcgttacgcc
    34921 aggcgctgcg atcattgccg cacctccgat accaaaggtt tcggtaatcg cgctatcgcc
    34981 catatccggg ttcgcctgct cctgcgagaa gccggtgaaa aacagacctt gcggagtgtt
    35041 tacaggcgca gtaaaccagc gttcgcccag cccgcttacc cgaatcccga acatattgcc
    35101 gttgcgggtc attgccgtga cgatgctgcc tgcgcggatc atcgcgccag catccatcgc
    35161 cgccttgcag taagccatcg cgaggttgag gaagaactga tcggtcacgc tgaggaaatc
    35221 catcacttcg gcgatgtgct gtttatcatg atcgaggcga gcaatttgtg gggccagcgc
    35281 acgcattaac agtgcagagg aagcaatatt gcgttgatgg aactcatcgc ccatcgtaat
    35341 gccctgcgcc atcatcgccg tgagatcgat accgcgctcc atgcgcccca gcgccgcgct
    35401 taatactggc attaacacat cgcgcatcca gcgatggcga gtcaggacat cttcgccgta
    35461 agcgccaaaa cgcatcactt tgccgatacc ttcgttgaga ttgcagtacg cccggttgcc
    35521 gtcggtcacg ttctcaacca ccagcatcgg catactggca gaagtaatac cgcccattgg
    35581 cccgacggca ttcacatggt gacaaggaat gaagttcact tccccctgct ccagtattgc
    35641 cagcgcctgc gcttcatctt tcgcccaacc ttcgaacaga catgcgccca cgcacgcccc
    35701 tttcatgggt ccggtcatct cctgccagcg cattggcggc ccggcgtgaa gcagtgtttt
    35761 gccctcgttt agttcgctga taagtgaaga agccggttgc acatccagcc agtgtggacg
    35821 agcgcgacga atttgttcga taaccgcagc attggcttgc gccactgatg taaacatggg
    35881 aaccccttat tgcaaacgtt ctaataaacg agccagtttt ttattgccac cggcgactgg
    35941 cgaccattgg taatgcacaa ccggtttgct ggcgctttgt agctccagcg caaagctgcg
    36001 taatccgatg ttaatcacgg cgacgttttc cagtaatgac ggtgtgtgtt gctgtgcggc
    36061 aggcgagagc ggatgaatta acgctgccgc cagcaaggtg gcttccggta gcgaactcac
    36121 gaccgcaatc cccgcatctt ccagcgtggc gatttgctgc gagcggcatt gcgggtcacg
    36181 ttcagtgcct gtcaccgtgg caatggcata cagtggttga ttatctaaac gcgcggcaca
    36241 ggctttttgc caggcgctca ccagcgaggc ggcaggatcg gcggtcgcac cgaagccaat
    36301 cacgacatca agcagcaaca cgcgcacttg cggtttagcg ccgagatcgg caattaactg
    36361 gttgcgtaag gttgggtcga tcatcggatg gggacgcccg acggtgtaga aatcatcgcc
    36421 gaggtcaata atctggtggc tatcggcgtc cagcatcatg ccatgttgat gggtatcgtc
    36481 ggcttccacg ccaaggtgtc cggcaagtaa tcccgccgct tcggcagcca gcgtaccgcc
    36541 ggtatacaaa ccgcaaataa atccgctgct gacaggcgct attgcgttac gtcgcgccgt
    36601 gacgcgtgaa agcaggcaag ccaggcgtgc ggcctcatcc agcgaggagg caaaccagac
    36661 attctcgtcg cgggccaccg ccggggtata acctaaaaac agcgccaccg tcggtttgcc
    36721 ggttgctttc atggcattaa caattttcag acgcacagct tcggcaggtg gttttgaaac
    36781 aaatgccagc acttcgcttt tctcgtctgc actgagcatt tccagcgctg ttagcgcact
    36841 gatgccgccc acttcacggc tgaggtcgcg cccgccaagg ccaatcgcgt gagtaattcc
    36901 ctcccctgcc agcgcaatct gcgaacacag ctcctgaatc ccggtaccgg aagcgccaat
    36961 gacgccaata ttgccttccg gcatcacgtt agcaaaagcc agcggtgtgc cggcaatcat
    37021 cgacgtaccg cagtccggcc ccatcaccag caagcctttt tcccgcgcgc gggttttaag
    37081 ttggatttca tcttccagcg tgacgttatc ggagaacatc atcacgttga ggttgcgatc
    37141 cagcgcctgg tttgccagct ccgccgcata ctcgccagcc actgaaatca gcgccagatt
    37201 ggcatcgggt aatttctgac aggcactgtc ccagcgacgc acctgcatca acgcctggct
    37261 gctgcctgac ccctgcgcca gttgttttag cgcctcttca agctgctgca taatcgcctg
    37321 cgcgatcccc gcatccgccg cttcgctacg aattgccacg caaatatcgt tcggcgtggc
    37381 gttattaaaa tcgtcatgcc agaaacctgt ggtatctaat aacgctttat tggcgggcgt
    37441 acccatcatt acggaaacat catcaacatt ttctgattcg ctgagttttc gtgaaataat
    37501 cattaaactg accgaatcct gaaaacaccc ttttttaata aaggcgtgga tcataacaac
    37561 tccttaaaaa ttgcacccat ggcaattgca cgagcagtgt taatgtggcg attacggtat
    37621 cgatgacaac gagtaaataa ggtgatgaat atcacacagg aattattaac aaaagaattc
    37681 aaataaccac caggctatta ctcattattt tttaataagc gttgttgttt taaaaatcag
    37741 gttaaaagtg agcggattat caaataaatt ctaactatat ttttttgcct gtctggatca
    37801 cataatccag atattttccc tgtatgttaa ttgcagtcat gcttcacacc gtcgttaaaa
    37861 aggaagacag atgaaaatca gtcgggaaac actccaccag ctaattgaga ataaactctg
    37921 ccaggctggg ttaaaacgtg agcacgctgc aaccgtggct gaagtattgg tttacgccga
    37981 tgccagaggg atccactctc atggcgcggt gcgcgtggaa tactacgcgg aacgcatttc
    38041 aaaaggcggc accaaccgcg aaccggagtt tcgtcttgag gaaaccgggc cgtgctcggc
    38101 aattttacat gccgacaatg ccgccggaca ggtcgcggcg aaaatgggta tggaacatgc
    38161 catcaaaacc gcccagcaaa atggcgttgc ggtggtcggt atcagccgga tgggtcacag
    38221 cggcgcaatc tcttattttg tgcagcaggc agcccgcgcc ggattcattg gcatttcgat
    38281 gtgccagtcc gatccaatgg tggtgccgtt tggcggcgcg gaaatttact acggtactaa
    38341 ccccctggcc tttgccgcgc cgggagaagg cgacgagatc cttacctttg atatggcgac
    38401 taccgtacag gcatggggaa aagtgctcga cgcccgctcg cgtaatatgt ctatcccgga
    38461 tacctgggcg gtcgataaaa acggtgtacc aacaaccgat ccgttcgcgg tacatgctct
    38521 gctccccgcc gccgggccaa aagggtatgg cctgatgatg atgattgacg tcctctcagg
    38581 cgtcttactc ggcttaccgt tcgggcgaca ggttagttcg atgtatgacg atttacacgc
    38641 agggcgtaat ttggggcaat tacatatagt tattaatccg aactttttct cctccagcga
    38701 attattccgt caacatctta gccagaccat gcgcgaatta aatgccatta cccccgcgcc
    38761 cggttttaat caggtttatt atcccggaca ggatcaggat attaaacaac gcaaagccgc
    38821 cgtcgaaggc atcgaaattg ttgatgatat ttaccagtat ttaatttccg acgcgcttta
    38881 taacacgtca tacgaaacga aaaatccctt tgcgcaataa ttattgagac aggactttct
    38941 tatgattaca catttccgtc aagctataga agaaacgctg ccctggcttt cctcttttgg
    39001 cgctgaccca gcgggtggga tgacccgttt actttattcg ccggaatggc tggaaaccca
    39061 gcagcaattt aaaaaaagaa tggcagcaag cgggctggaa acacgtttcg atgaagtggg
    39121 gaatttatac ggtcgcctga atggcaccga atatccacag gaagtggttc tgagcggttc
    39181 gcatatcgat accgtggtta acggcggtaa ccttgacggg caattcggcg cgctggcggc
    39241 gtggctggca attgactggc tgaaaacgca atacggcgcg ccgctacgta cggtcgaagt
    39301 ggtggcgatg gcagaagaag aaggcagccg cttcccgtat gtcttctggg gcagtaaaaa
    39361 tatttttggg ctggcgaatc ctgacgacgt gcggaatatc tgtgatgcca aaggaaatag
    39421 ttttgtcgat gcgatgaagg cttgcggatt tactcttccg aacgccccac taactccgcg
    39481 tcaggatatt aaagcctttg ttgaactgca tattgaacag ggctgtgtgc tggaaagtaa
    39541 tgggcaatca attggcgtgg tgaatgcaat tgtcgggcag cgtcgttata cggtaacgct
    39601 gaacggcgaa tcaaaccatg caggcaccac gccgatgggt tatcgtcgtg atacagttta
    39661 cgctttcagt cgcatttgcc atcagtcggt cgaaaaagcg aaaaggatgg gcgatccgct
    39721 ggttctgacc tttggcaaag tagagccgcg cccgaatacg gtaaatgtgg tgccgggtaa
    39781 aaccacgttc accattgatt gtcgtcatac cgacgctgcc gtgctgcgcg atttcaccca
    39841 acagttagaa aacgacatgc gggcgatttg cgatgaaatg gacattggta ttgatatcga
    39901 tttatggatg gacgaagaac ccgtgccgat gaataaggag ctggtcgcca ccctgacaga
    39961 attgtgtgaa agagaaaaac tgaattaccg ggtgatgcac agtggtgccg ggcacgacgc
    40021 gcaaattttc gcgcctcgcg taccaacctg catgattttt atccccagca tcaacgggat
    40081 cagccataac ccggcggaac gcaccaatat taccgacctt gccgaagggg tcaaaacgtt
    40141 ggcactcatg ctttatcaac ttgcctggca gaaataagga gtcataaatg ggatatttaa
    40201 ataacgtcac cggttaccgc gaagatttac tggctaaccg tgcgattgtt aaacacggta
    40261 atttcgcact gttaaccccg gatggtctgg taaaaaatat tattccgggc tttgaaaatt
    40321 gtgacgcgac aatcctctcc acgccaaagc tgggtgcctc ttttgttgat tatctggtca
    40381 cactgcatca aaacggtggc aaccaacagg gcttcggtgg cgaaggcatt gaaacgttcc
    40441 tgtatgtgat ctctggaaat atcactgcca aagccgaagg caaaacattt gccttaagcg
    40501 aaggtggcta tctttattgc ccgccaggct ccttaatgac gtttgttaac gcccaggccg
    40561 aagacagcca aatcttttta tataagcgcc gctatgttcc ggtagaaggc tatgcaccgt
    40621 ggctggtttc tggcaatgcc agcgaactgg aacgcattca ttatgaaggc atggacgatg
    40681 ttattctgct ggattttctg cccaaagagt taggttttga tatgaacatg catatcctct
    40741 cttttgcacc aggtgccagc cacggttata tcgaaacaca cgttcaggaa cacggtgcct
    40801 atattctttc cggtcagggg gtttataacc tcgacaataa ctggatcccg gtgaaaaaag
    40861 gcgattacat ctttatgggc gcttattctt tacaggctgg ttatggtgta gggcgtggtg
    40921 aagcgttcag ctatatttac tcgaaagatt gtaaccgcga cgtagagatt taagtcatac
    40981 cactcgcctg attattttta gctatgttgg attttgccac ggtttatacc gtggcttttt
    41041 ttgtaacatt gcctgatgcg cttcgcttat caggcctaca tgatctctgc aatatataga
    41101 atttgcgcga ttttcaggaa ggatatggta ctcatgccgc atccggcatg agtactgcac
    41161 tcttatgcga tataaatcgc atccgcttta aagataaggg ttagttttta attccctgac
    41221 ctattttaat ggcgcaggca atatttcgcg cgctgttgaa gagattggtt tcaccgctgg
    41281 cgagcacttc ggctaaaggt gccagacgag gcaaaatgct gaataccgcg tcaatgccgt
    41341 actggtgcac cacttccacg ccatcaccca atacgccagc aatcccaatc accggtacat
    41401 taaactgctt cgccaccgac gccacaccca gcggcgcttt accgcctgcc gtttgcgagt
    41461 cgatgcgccc ttccccggta atcaccagtg ctgcgccctg cactgcctgc gcaagattga
    41521 ccgcattcaa cacaatttca atgcccggtt taatatccgc attgagaaat accgccgccg
    41581 caatacccat accgcccgca gcgccgccgc ccgccatctg gcagacatta atttcagttt
    41641 gctgttgtaa aacacgggcg taattttgca gcccctgttc aagttcttcg accatctccg
    41701 gcgttgcccc tttttgcggg ccaaacaccg ccgccgcgcc gcgtgcccct accagcgggt
    41761 tatcaacgtc acatgctact tcaatatggc aattcgccag acgcggatcg cattcatcca
    41821 tctcaatgct tgccacgcgc gctaaattac caccgtttgc cgccagcgcc tgaccgtcgg
    41881 catcaaggaa acgcacaccg agcgcctgcg ccatgcccat accgccgtcg accgtcgcac
    41941 tgccgccaat gccgagaata atatggcgaa tgtcgttatc cagcgcatga cgaattaact
    42001 cccccgtacc aaaactggag gccagcaacg gattacgctt ttcaggcgcg accagcatca
    42061 ggccacttgc tgccgccatc tcaatcaccg ccgttttccc gtcgccggta aggccataaa
    42121 aagcattcac tttttcgccc atcggcccgc agacttcaag cgtcacgatg ttgccgcccg
    42181 tcgcggcgac catcgcatcc accgtccctt cgccgccatc cgctatcggc aaacagatat
    42241 agttcgcatc gggaaagagg gtcgaaaacc cggctttaat tgcctgacaa catttttctg
    42301 cacttaagct ctctttaaaa gagtctggcg caatgacaat cttcattatc aatccttttt
    42361 caacaaatta ttcgatgcgt tcccacggaa taaggttatc cataagaaca gccagtaaaa
    42421 tcccgaccaa taagccgtta ctgagcagag gacgaagcgt taatggaagg tcttgcagat
    42481 acacaggcgg taatgccatt aaaaatatgc cgacaaataa cggcaatgcg agtcgataaa
    42541 tattgcgagc ggtaaacgtt atttgctggc taaacaccag cgcggaaaag agtaaaggca
    42601 gataagaaac cagcatgacc gcactactca cgggtaaagg gatactgcaa aacagtcgcg
    42661 tgagtgcagg aaccagcgcc accagcaggc aaataacgct gccataaata aacgaacgcc
    42721 gcgtgtaatc gccagtctgg gttaataaac caatggatga aacaaacggt gaaaatggaa
    42781 ttaccgccag cggtacggtt atcagcgtca taaatccggt cgccacaaag ctacgacgat
    42841 aacgcgtatt ccctgcgccc tgctgcggat aaaaaacatc cgtgccccga atcgcaccgt
    42901 aggtattgct gatatttacc agacctgtaa tcaccgccgt cagaataatt cccggcgaca
    42961 aagcaccgcc actgccgagc gggaaccact gccagtgcaa ctcaccggag agcgagtgcg
    43021 aagaaggaaa gcaaaagtac cacaacaacc agccggttat ggtgccgacc agcaggccat
    43081 aacgggcaaa acgttgcggc aggaagataa tcatcgccag taccaggcac atcaccgcca
    43141 ccgagagcgc gaacggcggt aactgaattt taaaattcgg gtcggctatg ccaaacggca
    43201 gcccgagcat acctttgaaa aagatagtgg tcagctgcgc gcccagcatc aacataaaca
    43261 agaccatcac cgacggcgta aataaccgtg ccaggcgatg gcctaatccg ctaaaaccaa
    43321 tcaacatcgt cagcacgccg gagagtgcaa tccccactgc caggctggtg gcgatatcgt
    43381 tgatcggtgt cccgcgcgat gcttcaccaa gggtgatagt aaggatggtt ccccaccaca
    43441 ggccacctgg cccttccata atagcgcgac gatgaccgca aaacgcctga gcgaagcagg
    43501 ccagtgcggt agcaagaaaa gcatattgcg tgagcgtaag caggctactt tgcggcaact
    43561 gaaaagcaga aagtagcgta ggaggaacca caaccgtgtt gcaaaaaata aagaaaaacc
    43621 actgaaatcc tgataacagg ctttcgcggc tgactgcaaa attgaacata aacacacctt
    43681 aaccggagaa tgcccgccgc aaggacgggc attgcagggg ccagattact gctgatgttt
    43741 aaggataaat tgacctttcg gcgcaacagg gaagccctgt tcaatgtcgt aaatcacatc
    43801 accacgtaag atggttttcg tgatacgcgc gccaatggta cggccaacat acgggctgac
    43861 tttgtggcga tattccagat cgtcattggt aagaacatag ctgctattcg gctgaatgaa
    43921 gacgaagtcg gcatcttttc ctggggcgat acggcctttt tgctgcagac cgaaaatatc
    43981 tgctgcgtta gtcgccatta atttgccgaa cattggcaga gacataccgc gtttctgtac
    44041 cgcttcatcg aacatcacgt ccatgcagct ttgcagaccg gcgataccgc cccatgcttt
    44101 catgatgtta ccggctttca tttccggcgg gcatggagag tggtcggaaa ccaggcagtc
    44161 gatttcaccg ttaaacagtt tttcccacat gcctttctgg ttttccagat cgcggatcgg
    44221 cggtgaacac ttcgccagag taccgatttc ttcgaactga tcggtatcca gtacaaagta
    44281 atgcgggcag gattcacaag taacgtcctg accttcctga cgtgcacgag tcacttcctc
    44341 aacaccttcc gggctgctga cgtggcaaac gtgcagacgg caaccagcaa ctttcgccag
    44401 atacagtacg cggcgaattg cttccacttc ggtaaatacc ggacgcgaag ccacatagtc
    44461 atgagcggtt acgcgacctt cacgcttcgc ttcttcgccc agttcgtcac aaatcagcgc
    44521 gttttcgcag tgcaccagca ccggctgacc cagttcgccc agcttctgcg cacctttgaa
    44581 gaactgccag tcgtttacat cacggaagtc gttgtcgata ccgcgatcgc cacaggtcgc
    44641 aacgaagcat ttgaagccga caacgcccac ttcatccagc tcatgcagac ggtcgatgtt
    44701 gtaagacacc aggccaccga gttgtgccgc atcaatagtc agcttgcctt tagcggcatc
    44761 gaacttcagt tcaattgaag cgcggtcaac cgttgcaggc agctggttga gcggcatttc
    44821 gatcatggtg gtgataccac cttttgccgc tgcgcgagta ccggtttcat aaccttccca
    44881 gtggctacga cccggttcag aaatatgggt gtgcgcatca accatgcccg gcgaaaccac
    44941 cagaccagac gcatccataa cttcttttgc atcgcccaga tcctgaccga tagcagcaat
    45001 ttttccgcct ttaacggcga tatctacaac gcgagcttcg ttttctaaaa taacggtgcc
    45061 gtttttaatg attaaatcaa aagacataac aaactccttg taaaatacag attggttttt
    45121 aactcaatgt tcaatatcgg gattaattaa cctatggttt tttgctctcc tgttttttct
    45181 gctgttgtac gtttctttaa taaggcgtag gccgcaaagg cgacgatgac gccgacaaac
    45241 catgaaacac gcgataacgg ttccataaag tgaataaact taccgccaag agataaaata
    45301 acggccacca gagttactga aaacgcagtg aggttaaaac cgttatcgta atatttataa
    45361 tcgccaggtg cggtatacag ttcatcaaga ttaatttgtc cgcgcatcac cacaaaataa
    45421 tgcgccatca tgacaccaat taccggacca agcattccgc cgataatatc gaggaaaaga
    45481 taaatgctgt cctgattttc cattaatttc cacgggcaga tcagcaagct gataatactg
    45541 gcaatcagta cgccgttttt ataggtcagt tttgtcggtg caatggcggc aatctgataa
    45601 ccggctggaa taatattacc ggtcgcgtta gtggagatag ttgtcatcag aataaccagt
    45661 accgcaaaga acgaggcgaa caggctgtcc caacgctgaa caatatccag cacgttccag
    45721 gtatcagcgc cgtagtgaat actggctccg gcaataatac ataccccggc gaccgcaaac
    45781 agaatatagg ccacaactaa acccagcgtt tgccccagcg cctgctcacg aaacgagtgg
    45841 gcgttttgcg taaagtcgga tgcgctcacc gccggtgccg cccagaccgc aactaccgcg
    45901 ttaatcacca ccaggaacag gaagccaccg ttttctgctt tctgaatacc gctcggaatg
    45961 tagtcaaaga ttggaccgat cccgaccagt gaaatcgccc aaatcgccat accgccgaaa
    46021 acgatataga tgcacgggtt aagaatggca gtgaatttat ttaaaacttt gccaccgcca
    46081 aaacctatac caacgttgac cagccagaag attaagaaag taattaagcc cggtagagaa
    46141 aggcctaaca gagtgaaatc accaccgaga gttaaaaatc ccggccagat tttgccaatc
    46201 agaatcaagc aggccagtga ccccgcgtaa cattgcaaac caaaccacat gatggcggca
    46261 attccgcccc ttaataatcc gggaaacagt gcaccacgta caccgtaaga agcacgcagg
    46321 atcatggcaa aaggcacacc gtatttactg cccgcagcac cgtttaatac cattaccgcg
    46381 gcaatgaaaa aggcgctgag gataattgcc agcataatac taaaggtaga caagccgaga
    46441 ataaaaaagc cgccgaccat cacataattg ggaacgttat gaaccgaacc catccataag
    46501 gtaaaatagt taaatgtttt ccaggtccgc tggctttgcg ttttcggcaa tagatcttcg
    46561 ctatagccgc gttgctggaa tagttttctc tgatgttcca taaatccctc ttaatttcac
    46621 gtatcgaata acgttgtttt aatctagcta tgaggaacaa ataaaataaa aatattattt
    46681 ttaatactga agcaacatct ttggctgctt tcttttttaa tattgctggc cgattcattt
    46741 tctgatatcg gccattttta ttgcgggtat caggccagtt tatggttagc cattaattcc
    46801 agcgcctgca ctaacgcaga gtgatccaac tggctgccac cgtttgccgc acaggtatta
    46861 aataactcct ggcaggtcgc agtgtttggc aggttcagcg caagtgcttt cgcactttgc
    46921 agtgccaggt tgagatcttt ctggtgcaga gcgattttga agcccggatt aaaggtgcgt
    46981 ttaatcatac gctcgccatg aacttccaga atacgtgagg aagcaaagcc gcccatcagc
    47041 gcctggcgca cacgtaccgg gtccgcaccg gcttttgaag caaatagcag ggcttcagaa
    47101 accgcttcaa tattgagcgc cacgataatc tgatttgcca ctttgcaggt ttgaccatcg
    47161 ccgttaccgc ccacgagggt gatattttta ccgagcagtt caaacagcgg tttaacacgt
    47221 tcaaataccg cttcatcacc gccaaccata atcgacaacg tcccttcacg cgcaccgatt
    47281 tcaccgccgg agactggcgc atcgagataa tcgccgccca gttcattcac ctgacgagcg
    47341 aaacgcttag tttcaatcgg ggaaatggag ctcatatcaa caatggtttt gcccttcagc
    47401 gaggctttgg tacaaccatt ttcaccgaac agaacttctt caacctgagg tgtgtccggc
    47461 accataataa aaatgatgtc cgatgcttcc gttacctggc gagcagtttc aacactgacg
    47521 gcacccagtg acagtaattc atcagcaacc ggtccaatgg tcgtgacatg taattgatga
    47581 ccggcacgcg ccagattaat ggccatcggt gtacccataa tgcctaagcc aataaatccc
    47641 agtttcataa ttaacctctt ttaaatttcg cttttcctga attcagacaa cacgatcccc
    47701 tgccaactta gcggcctaaa aaagcattgt ctgaatagcg ttacgtttta acggtacgga
    47761 tccatccagc gtaaaccggc ttccgtggtg gtttggggtt tatattcaca cccaacccaa
    47821 ccgttgtagt cagaattttc gattacctta aagagataat cataattaat ttctccggtt
    47881 cccggttcgc cgcgatgcgg attatcggca atttgcaggt gaccaatttt atcagcccac
    47941 tgagtcatgg tgttggttaa ttcaccttcc atccgctgca tatgataaat gtcatactga
    48001 attttcaaat tgcagcaacc aacatcatca atcaatttca gcgcctgccg agttccggtg
    48061 agatggaaac caggaatatc aaaatggtta ataggttcaa tcagtaataa aatatcttct
    48121 ttcatcagca tattcgcggc ataacgcagg ttttctacaa gcgttgcgtg aatctgttca
    48181 ctgctgaaac cagccggcgt tttaccgacc agacagttaa tttttttatt acccagcgca
    48241 cgggcataac gaatcgctgc tgctacgcca tcccgaaact cttcttcacg gccaggaata
    48301 caggcaatac cgcgctcccc cgccgcccag tcacccgccg gtaaattgtg cagcgtatgt
    48361 tcgagtttat tactcgccag cacatgtttt aattcttcaa tgtcgtagtc ataaggaaac
    48421 ataaattcaa cgccgcgaaa accacactgc gcagctttct caaaacgggc gagaaaatca
    48481 tattctccaa ataacatcga taaattagca gagaaacgta acattattta tctcccttat
    48541 tcatagtgca tgaagcaggt ttcagtcggt gcgtccgctg cgttatcggc gatatcttca
    48601 aattccatga cgttatccag ttcgctgccc atcgaaatat tggtcacacg ctcgagaata
    48661 acttccacaa ctaccggtac ccgatattgc gccattaagg ctttcgcctg ttcaaaggct
    48721 ggcgcaatat cttccggttt gaagacccga atagctttac aacctaaacc ttccgctact
    48781 tttacgtggt caacaccgta gccattcact tcactggagt tgatattctc gaaagcgagt
    48841 tgcacgcagt agtccatgtc aaaagcgcgt tgtgactgac gaatcagccc cagataagcg
    48901 ttgttgacca gcacatggat gtacggaatg ttgaactgcg cgccaacagc taactcttca
    48961 atcaggaact ggaagtcaaa gtcgccagaa atcgccacca cattgcgttt cggatcagcg
    49021 gcacaaaccc ctagcgcagc cggaatcgtc cagcctaacg gaccagcctg accacagttg
    49081 atccagtggc ggtctttaaa gacatgcagc atttgtgccg cagcgatttg tgacagacca
    49141 atggtggtga cataacaaac atcgcgacca aaggctttgt tcatctcttc atacacgcgc
    49201 tgcggtttca ccggcacgtt gtcgaagtgg gttttgcgca gcaaagtgcg tttacgctgc
    49261 tggcagtcgg cgacccattc tttacgacac ggcagacgac ccgctttttg catctcctgc
    49321 gccacttcaa ccagtagtgt cagcgccgct ttagcatcag agacaatacc gagatccgga
    49381 cacagcacgc gaccaatttg cgtcggctca atatcaatat gaacgatttt gcgcccttcg
    49441 gtgtatttct ctaccgagcc ggtatgacgg ttagcaaaac ggttaccgat accaaacacc
    49501 atgtcagacg ccagcagcgt tgcgttaccg taacgatgcg cggtttgcag acccaccatc
    49561 ccggccatca gttcatgatc gtccgggata cagccccagc ccattagcgt tgggatcacc
    49621 ggaacgctgg tcagttcagc aaactgttgt aacagtgcag ctgcgtcagc attaattacc
    49681 ccgcccccgg caacaatcac cggacgttcg gcctggatta acatttctac agctttttcg
    49741 atctgcatac ggctggcagc aggtttgtag accggcagcg gttcgtacat gtcaggatca
    49801 aactcgattt ccgcaacctg aacgtcgaac ggtaaatcca ccagtaccgg acccggacga
    49861 ccagaacgca tcaggtgaaa tgcctgttgc agcacgcgag gcaccagcgc cgcttcacga
    49921 actgtaaccg ccattttgct gaccggttta gcaattgctt caatatctac ggcctgaaaa
    49981 tcttctttat gcagacgggc gcgcggtgcc tggccggtaa tgcacagaat aggaatggaa
    50041 tcagcagaag cggaatagag cgcggtgatc atgtccgtgc ccgcaggacc ggaagtcccc
    50101 agacatacgc cgatattccc tgccgttgcg cgggtataac cttccgccat gtgcgaagca
    50161 ccttccacat gacgcgccag aatgtgacga ataccgccgt gcttacgcat cgctgagtag
    50221 aacggattga ttgcagctcc cggaacaccg aaggcggtag tgataccttc tttctccagc
    50281 acatacattg ccgcgtcaac ggctctcatt tttgccattt tattcctacc tctatttatt
    50341 ggaaaatttt tccaactttc aaattttgtc aaaaaaaccc gctccgcaga gcgggatgcg
    50401 acagacatta tggatgtgct ttcagtccca acgccgtgct gatatcgcgg gcggtgtctc
    50461 tgaccagctc accctgactg acaaaacgat cttctgtcag tcttgatgaa ggcccggaga
    50521 tggagatagc ggcaacaaca ctaccgacat catcgtaaat tgctgaagct atgcaattca
    50581 gacctacaac atgctcttct ttatctacgg tatagcccag ttcacgcgct tgttccaggt
    50641 ccttcagcaa ggtgggcata tccacaagcg tagttggcgt aaactgctgc aaaccggttt
    50701 gcagaatgat gctcatcaac tcctcttccg ccagcggata aagcagcgct ttgcccgcac
    50761 cggaagcatg cagtggcaga cgactgccca gtggcgcaca catcctgacc atcgatttac
    50821 actctaactg accaattaat accgcttcat tgccgttacg gatcgcgaca ttgaccgttt
    50881 cgccggaaag taacatcagg cggcgcataa acggcccggc gacggagagg acatcgcggt
    50941 tatggatgta cgccgcaccg acgttaaaga cacctaatcc tatatgccac cagcctaatt
    51001 gactgtcctg atagacaaaa tccgctgcct gtaaaacctt cagcaagcga aaggtcgtgg
    51061 agagcggcaa atccagattg agagaaatat cgctaaccga cgaacttccc ccactttttt
    51121 ccaaatattg cagaatcgca attccccgct ctaacgcctg tgcgcccttc tgtgccacag
    51181 gctccgcctg tcctggcctg ccgcgccgtc taacttccgt catacctacg ttaactccga
    51241 cctacaagtg agcataaaca atgaacaatt agtttatctt atgcaagtcg gttgcaggcg
    51301 tcacgcaaaa cagagttcct gttcaggaat actttcaaca tcacagttgt cactgccgcc
    51361 gcgatcgatg gtcagaaaat cggtgacgcg ctgccaggcg aaaagtgggt gatgccagac
    51421 gttacgatgg taattcactc cctgttcgcc gttggtgata aacgcccgca gcgttgacag
    51481 gtctggtttg tcgtcaccta acgccacgac caccacaaac acctcacctt tcatcgggat
    51541 aaaggcctga gtacccagcg gatgacgttc gagttcgtga atggtcagcg gcagattcgc
    51601 cggttgcgcg cggttaatgc tgataagcgt acggtcttgc tcaagaatct caaccagcgc
    51661 caaatcgtgg taacgctcca ccaggccatt gttaatatgg aaaaaatccc gttgctgcgt
    51721 ttcgattacg tcgccataag cactaaaggc ttcctgactt aacggtaata cctgaagttt
    51781 catctttttg tccttgtaac ataattccgt tcaaccaccg ccgaccggtc agcttggttt
    51841 caataacagg caatctaaaa ccttaagaga acaacatcaa tacaaaagtt ggaatatttt
    51901 tccaaaacta gatttagtcc acaaattgaa cagggttatc atgtaaaaat actgataaat
    51961 cagaggataa gaaaatcacg caacttgcgg atttaaaagg ggatacctga agatgttcga
    52021 tccagaaacc ttgcggactt tcattgcggt tgctgaaaca ggaagttttt caaaagcggc
    52081 agaacgatta tgtaaaacca cggcgacgat cagttatcgc attaaacttc tggaagagaa
    52141 taccggagta gcgctgtttt tccgtacgac tcgcagcgtg acgttgacag cggctggcga
    52201 gcatctactt tcccaggcca gagactggct gagctggctg gaaagtatgc caagcgagct
    52261 gcaacaggtg aatgatggcg tggaacgcca ggtgaatatt gtcatcaaca acctgctcta
    52321 caacccccag gccgtcgccc agttgctggc gtggctgaat gagcgttacc cctttaccca
    52381 gtttcacatc tcccgacaaa tctatatggg cgtctgggac tcgctattgt acgaaggttt
    52441 ttcgctggct atcggcgtca cgggaactga ggcgctggca aataccttta gtcttgatcc
    52501 cttaggatcg gtgcaatggc gctttgtcat ggcggcggat catccgctgg cgaacgttga
    52561 agagccgcta acagaagcgc agttgcggcg ctttccggcg gtcaatattg aagacagcgc
    52621 ccgcacctta accaaacgcg tcgcctggcg attgccaggg caaaaagaga ttattgttcc
    52681 cgatatggaa acgaaaatcg ccgcccatct ggcgggcgtt ggcattggtt ttttgccaaa
    52741 atcgctttgc cagtcaatga tcgataatca acaactggtc agccgggtaa tcccaacgat
    52801 gcgccctcct tcgccattga gtctggcatg gcgcaaattt ggcagcggca aagcggtaga
    52861 agatattgtg accttgttta cccagcgcag gccggaaatc agcggatttt tagaaatttt
    52921 cggcaaccca cgcagttaaa aatcaagttt ccttgcgcgt tggcgcgtaa aatagcgcgc
    52981 aagctgattt gaggttcact tttaactatg caagagagac acacggaaca ggactatcgt
    53041 gccctgctga ttgctgatac gcccattatt gatgttcgcg cccctatcga gtttgagcac
    53101 ggcgcaatgc ccgccgctat caatctgccg ttaatgaata acgatgaacg cgccgccgtt
    53161 ggcacctgct ataaacagca aggctcagac gcagcgctgg cgctgggaca taaactggtg
    53221 gcgggtgaaa ttcgtcagca gcgcatggac gcctggcggg cagcgtgcct gcaaaatccg
    53281 caaggtattc tctgctgcgc ccgtggcggt cagcgctcac atattgtgca aagctggttg
    53341 catgcagcgg ggattgatta tccgctggtg gaaggcggtt ataaggcact gcgccagacc
    53401 gcgattcagg cgactattga actggcacaa aaaccgatag tgctgattgg cggttgtacc
    53461 ggcagcggta aaacgctgtt agtgcagcaa cagccgaacg gtgttgatct ggaagggttg
    53521 gcgcgtcatc gcggttcggc gtttggtcgc acgttacaac cacaacttag ccaggcgagt
    53581 tttgaaaacc tgctggctgc cgaaatgcta aaaaccgacg cccgtcagaa tttgcgcctg
    53641 tgggtgctgg aagacgaaag ccggatgatc ggttcgaatc acctgccgga atgcctgcgc
    53701 gagcgaatga ctcaggcggc gattgcggtg gtagaagatc cgtttgagat ccgtcttgag
    53761 cgcctgaacg aagagtattt cttgcgtatg catcatgatt ttacccacgc gtacggcgac
    53821 gaacagggct ggcaggagta ttgcgaatac ctgcatcacg gactttcggc gattaagcgt
    53881 cggctggggc tacagcgcta taacgaactg gctgcaaggc tggatgcagc actgacaacg
    53941 caactcacca ccggcagcac cgacggtcat ctggcctggc tggtgccgtt acttgaagaa
    54001 tattacgacc cgatgtatcg ctatcagctt gagaaaaaag cggaaaaagt tgtctttcgc
    54061 ggtgagtggg cggaagtggc ggaatgggtt aaggcgcggt aatgagggac gtatttgtat
    54121 tagtcgcgac ttgatctgac acatggcctt gaaaggttga gagttaccgg ttttgatatg
    54181 agtgtcgaat ccttatccaa aacaagaggt aactctcatg cttcatactg ccaatcccgt
    54241 catcaaacac aaagccggtt tgctcaatct ggctgaagaa ctcagcaacg tatcaaaagc
    54301 ctgtaaaatc atgggcgttt cgcgtgatac gttttatcgt taccgcgaac tggtcgctga
    54361 aggcggtgtg gatgcgcaga ttaatcgtag tcgccgcgct cctaacctta agaaccgtac
    54421 cgatgaggca actgaacagg ctgttgttga ttacgccgtc gctttcccga cacatggtca
    54481 gcaccgggcc agcaacgagc tgcgtaaaca gggggttttt atctccgaca gtggtgtccg
    54541 ttctgtctgg ttactccata accttgagaa tctcaaaaga cgatactgaa caaattttat
    54601 caggtgacgt tccgtaaaaa gttgtatgga gttctcgatg cagtcggcgc gactatcagt
    54661 acccccgctg aaccctggac tatcgggccg ccgtactggg gcatgtcacc ctggcgtgcc
    54721 gctggttttc cgctaatggt ttatttcctc tttctttccc ggcaagaatt tattttaatc
    54781 cggaaggatt atttattttc agatagggac tcacattaaa cacgtaacat tttaattaat
    54841 gcatggctga atatgtatta cacaatgtca gatatcgtaa aagaccagtg caattctatg
    54901 taaactctct gactgttcat tttatttgtt gtttcagggt cggaactcac cctcaataaa
    54961 caactgaata cgagtagata ttcatcgtct gagctatatg gctttacaca atagccgaca
    55021 tgtcttttct cagtcaggaa ttttactttt cctcactacg aagttgacga cttcgatatg
    55081 ggatagactc ttaattcaag caattactct gcacaagcat caggcaatcc agctccaata
    55141 tttgttataa aataatgcgt aacattaatt tcaccaacaa aaaaaaggtt tacaccatcc
    55201 ccttgccctg gtatcttacc atatttacac cacacttttt ttgtatctgg atcattcttt
    55261 gatacgattt tcgccacttg ttccctggcc ctcactgtca atgttttctt aaacctaccc
    55321 ccatcatcat ttgttaggga aaaataagaa aaaaataatc atcttctaca tttgtgtata
    55381 ttgatatatc caccgctacg tgcggaaaaa aatctgggag ccatgtaaaa actccatcat
    55441 tttctggtat tgccatatag tttatgtaat gtttacttac aagagattca tctttgtata
    55501 aataaagata agtaattacg cataaaacaa caatgattat aatagcaaaa ataaatatta
    55561 tcatctttga tagattactt gagatagcca gcatcttgta aagcctttat cgttttttta
    55621 tgctctggat taatataatc actacatcta tctgagcaat ctgttgttga tggacatgtc
    55681 aacccatggt catttacagc caagtctttt ttattatctt caatcatttc agaatgggat
    55741 agctttactt ttctgccgta cataccgaac agatttaacc cgtaatctct aatctctttt
    55801 tcataaccca gccctttcgc cgatcggcta acaccagcgt tatttaattt agacactcga
    55861 caaaatgcca tacaatggaa aaattgatca gtcccaccta aatttaatct cttcatatct
    55921 tcataagtat cagataatat atcccatgct ctttgatggt ttagttgatc ttttcttctt
    55981 attagcgcta catctgcggg acttaaccct aatggatcaa taccattcac cggattcagc
    56041 ggatacgcat acagactcca tcccccctcc agccctatcg ggtcctgagt gatataccgc
    56101 ccctgcaacg gatcgtagta ccggttccgg ttgtagtaca gccccgactc cttatcatac
    56161 tgctgccccg gcagccggta cggctggtgc aggtgatgcg ggttctcttc attcagctgg
    56221 ttgccccact catcatactc cccgctccac gcaatgtttc catccgcatc catcagcgcc
    56281 agcattattt actatgtagg aaattcaaaa cacatccatt tttcttatta atttctataa
    56341 taaatacacc acccgcaact tcataaggta actttgctcc ctcaacaacc caactatctg
    56401 gtagttccgt aattaaatat ggtttttctt cttctgcaat ccgttcgcca tagcgatacc
    56461 taacatatat ttcagctaat tgtatcgcca ttgtttcagt ttttaccgta tttttaacag
    56521 agtatttatc taaatgtaat ttttccacat acctcataaa aataatgttt tcatcagaac
    56581 cgtaaacagc tgtctcatta caggcaaata gtataaaaaa tgaaagcatc gaaaatattg
    56641 aactatattt cattgaatct ccttataggc cccactaata aaagcactaa aattaatcat
    56701 gatacggtat gcatactgaa ctcaatcccg ggacactatt tctgataaaa atatattctc
    56761 ctttattatt aagcgcctca aatcgtccat caggtgttgc gagataaaat gcttcaagat
    56821 tattatcttt acttcttaca agatttttat cgctacttga aaaaaattca tcaacataat
    56881 cgccatgact atctgcaccg tgagtatgat aagcagcaac tctatctgta cctgtgggac
    56941 attttctttt cagaggatat gactcctttc ttaaattatc agtttctgcc ttagatgcaa
    57001 aatattttcc attagtatct ttacagacaa taccagagta ttccatatca ttacatagag
    57061 atctattctg cgtttctttc aaagcatcta acgcagcatc tgcagtacta tcaaatttac
    57121 ttggtcctat tatacgtgaa agaacaccac aaactccccc cgtacatgct ccagatctgg
    57181 catcatccca agtctgcaat aatcccatag ggtcaatttg ttgtagtgga tttaaaggat
    57241 actgatataa attccatccc cctttcaacc ccatcggatc ctgagtaata taccgcccct
    57301 gcaacggatc gtagt
//
LOCUS       DACAOP010000018        55122 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.018, whole genome shotgun sequence.
ACCESSION   DACAOP010000018 DACAOP010000000
VERSION     DACAOP010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 55122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55122
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.018"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..1902)
                     /locus_tag="IT892_001260"
     CDS             complement(<1..1902)
                     /locus_tag="IT892_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HAP3134495.1"
                     /translation="MLAQTARPELYIPDGFVKQTAAPSGYVESPVVRIYDQLNKPTKA
                     DLGLSNAMLTGAFGLGGSGISTNGKMSDVEILKALRDKGGHFWRGDKPTGSTATIYSH
                     GSGIFSRCGDTWSAINIDYSTAKIKIYAGNDARLNNGTFSINELYGSANKPSKSDVGL
                     GNVTNDAQVKKSGDVMSGDLDILKETPSIRLKSAKGTAHLWFMNNDGSERGVVWSPEN
                     NESLGEIHIRAKNTKGESSGDFIVRHDGRVEARNLKITYKISAATAEFANTSTSSDNT
                     TVSIKGSQHTPLVLTSNNTIKNLSIGFKVDDVDQKYLGIAGDGDLYFGSYSDHTKNSK
                     VITQAKLDSGVTVGGKTTFSDFATFNAGMAGSIEPETIDNKTIDLNDLIIANTVAGSV
                     KYYQCKTVAGGAYITNKPDGVSGNFLLRVESTRKTTGSDYAIMQTLIGSDTKRIYVRF
                     VVNGNWTEWSQVVVSGWNQDVTVRSLTSTTPSKLGGGRVDVLGSTSDYSSMNCAVRGV
                     DSTGTNSAWSVGTSESTGKMLFLKNHRSSAQVLLNGDDGAVQLLSGTVNGATAQALTI
                     NKDEVNSTADLVIRKQTGTGNRFALLNSGNSELPVSIRVWGSSTRQNVFEVGTSAAYL
                     FYAQKTTDGQ"
     gene            complement(2284..3276)
                     /locus_tag="IT892_001261"
                     /pseudo
     CDS             complement(2284..3276)
                     /locus_tag="IT892_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415890.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
     gene            complement(3341..3940)
                     /locus_tag="IT892_001262"
     CDS             complement(3341..3940)
                     /locus_tag="IT892_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HAP3134496.1"
                     /translation="MRKVYAAILSAAICLAVSGTPAWASEHQSTLSAGYLHARTNVPG
                     SDNLNGINVKYRYEFTDTLGLVTSFSYANAKDEQKTHYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGMAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVAVDVAYEGSGSGDWRTDGFIVGVGYKF"
     gene            complement(4008..7487)
                     /locus_tag="IT892_001263"
     CDS             complement(4008..7487)
                     /locus_tag="IT892_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HAP3134497.1"
                     /translation="MGKGSSKGHTPREAKDNLKSSQMLSVIDAISEGPVEGPVDGLKS
                     VLLNSTPVLDTEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVDNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPDNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISTGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGQGNPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVTADDGSEWLVSTARTTETTYRFTQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRITDIRQVETTARYLGTALYWIAASINIKPGHDYYFYIRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPDGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKRLTAPTITSGGNP
                     PVFSLTPDGRLTAKNADISGNVNANAGTLNNVTINENCRVLGKLSANQIEGDLVKTVG
                     KAFPRDSRAPERWPSGTITVRVYDDQPFDRQIVIPAVAFSGAKHERENNDIYSSCRLI
                     VRKNGAEIYNRTALDNTLIYSGVIDMPAGHGHMTLEFSVSAWLVNNWYPTASISDLLV
                     VVMKKATAGITIS"
     gene            complement(7548..8156)
                     /locus_tag="IT892_001264"
     CDS             complement(7548..8156)
                     /locus_tag="IT892_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HAP3134498.1"
                     /translation="MARICLYGDLQRFGRRIDLRVKTGAEAIRALAMQIPAFRQKLSD
                     GWYQVRIAGRDAGENELSARLNEPLKNGAVIHIVPRLAGAKSGGVFQAVLGAALIAVA
                     WWNPVGWLGAAAVSGMYAAGASMILGGVAQMLAPKARTPRTQTTDNGKQNTYFSSLDN
                     MVAQGNVLPVLYGEMRVGSRVASQEISTADEGDGGQVVVIGR"
     gene            complement(8093..8836)
                     /locus_tag="IT892_001265"
     CDS             complement(8093..8836)
                     /locus_tag="IT892_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP3134499.1"
                     /translation="MTQTESAILAHARRCAPAESCGFVVSTPEGERYFPCVNISGEPE
                     AYFRMSPEDWLQAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGAIHK
                     FRCVPHLTGRRFEHGVTDCYTLLRDAYHLAGIEMPDFHREDDWWRNGQNLYLDNLEAT
                     GLYQVPLSAAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWHVSAFTGICNDLAAASTFV"
     gene            complement(8842..9540)
                     /locus_tag="IT892_001266"
     CDS             complement(8842..9540)
                     /locus_tag="IT892_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HAP3134500.1"
                     /translation="MQDIQQETLNECTKTEQSALVVLWEIDLTEVGGDRYFFCNEQNE
                     KGEPVTWQGRQYQAYPIQGSGFEMNGKGASARPTLKVSNLYGMVTGMAEDMQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSYADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYSGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            complement(9540..9896)
                     /locus_tag="IT892_001267"
     CDS             complement(9540..9896)
                     /locus_tag="IT892_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001347380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP3134501.1"
                     /translation="MEDCTVPEPEVFNWIPREGMETTRKPSVITVKFGDGYEQRRAGG
                     LNADLKTFKPVFRVTDEYSRAALDSFLSRHAGIRAFLWRPPKHNRTVRVVCREWSISD
                     NAMYTDFNCTFEEVTH"
     gene            complement(9874..13101)
                     /locus_tag="IT892_001268"
     CDS             complement(9874..13101)
                     /locus_tag="IT892_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAP3134502.1"
                     /translation="MATLRELIIKISANSRSFQSEISRASRMGQDYYRTMQNGGQQSA
                     AASREMRRALAEVTDQINTAKSSALNMAGAFAGAFATGHLISLADEWNSVNARLKQAS
                     QSSDDFQASQRELMAISQRTGTAFSDNASLFARSAASMREYGYSSEEVLKVTEAISTG
                     LKLSGASTAEASSVIMQFSQALAQGVLRGEEFNSVNENGDRVIRALAAGMGVARKDLK
                     AMADNGKLTADKVVPALISQLGALRDEYAAMPDTVSSSATKVENAFMAWVGGANEASG
                     VTKTLSGVLNGVADNIDTVAAAAGALVAVGVARYFGNMASSAGSATAGLITAARNEVA
                     LAEAQLRGTQIATARARAAVYRAQQAVVAARGTERQAAAEAKLTAAQASLTRNIAART
                     AAQTTLNTVTSVGSRLLSGALGLVGGVPGLVMLGATAWYTMYQNQEQARESARQYAAT
                     IDEIRQKTSAMSLPEASDNEEKTRQALDEQNRLIDEQKSKIKSLQEKIAGYQYVLANP
                     GWTTDNGFMINHMTSVKTVTEGLAEATNQLAVEQSRLTQMQGKAQSIQDVLAGLEERR
                     VALIRQQAAEQNKAYQSLLIMNGQHTEFNRLLGLGNELLQQRQGLVNVPLRLPQATLD
                     DKQQTALNNSKRELALSRLKGEARERARLGYAADDLGFVGEAYQTARQNYINNSLDAW
                     RNNQANKPKAHKKTEAEKTEDIYKRLIKQQKEQIALAGQNTELAKMKYQVSQGELSTL
                     SEAQKKTLLQNAALIDQKKIREQLAAYESSLADSNASTRASNDAQLLGYGEGSRMRER
                     LQEMWSIRHEFEQKNNELLRQYQAGEIEEALWKQEKELNKKYLEERLSDQQDYYAKAD
                     ALRNNWNAGLQEGLTNWADSATDYASQAADAVVSTMDGLVSNISDALAGNVVDWRNWG
                     SSVLREVSKILMNAAIVNGLKSLSGAGGWLGTVGGWISGAVANAKGGVYTSANLSAYS
                     NTIVDTPTYFAFAKGAGLMGEAGPEAIMPLTRAADGSLGVRAIGDVNGGGGFVYSPVY
                     HISIQNQGSNGEIDARSARGLVDLIDSRVVSIMQSSRRDGGLYSA"
     gene            complement(13148..13408)
                     /locus_tag="IT892_001269"
     CDS             complement(13148..13408)
                     /locus_tag="IT892_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016809743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4035 domain-containing protein"
                     /protein_id="HAP3134503.1"
                     /translation="MGRTLSELRREMSASEIMMWAEFDRFSPLGDERADFRAAQIVSA
                     IYGAQGVKVSLNDALLQWEKEQTEGASDPFAGLENALLIVSQ"
     gene            complement(13450..13836)
                     /locus_tag="IT892_001270"
     CDS             complement(13450..13836)
                     /locus_tag="IT892_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001324129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP3134504.1"
                     /translation="MRMDVMTKNIRNLALATMSGFRHKTVDVPEWEGATVVLREPSAE
                     AWLRWQEIVKAKDDETPLSVAERARRNLEADVELFIDVLCDTGLQPVFSEDDREQVIA
                     VYGPVHARLLRQSLELISDAGEVKKK"
     gene            complement(13836..14540)
                     /locus_tag="IT892_001271"
     CDS             complement(13836..14540)
                     /locus_tag="IT892_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001735010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP3134505.1"
                     /translation="MSSNFERSQLTKIMISSAPVTAETLDSASYLGLSCTIKEVQFTA
                     GQKQDIDVTTLYSVEQENINGLGAASEISMSGNFYLNAAQNALRSAYDNDTTYGFKVI
                     FPSGNGFTFMAEVRQHTWSAGTNGVVAATFSLRLKGKPVLTTEQLKVKVDLKSTLRVA
                     SGAKLEMAVEAVGGVPPYSYAWKKGGSPVSGQTAATFSKASAASGDAGAYTCEISDSA
                     SPVNKVTSTSCTVTVS"
     gene            complement(14601..14945)
                     /locus_tag="IT892_001272"
     CDS             complement(14601..14945)
                     /locus_tag="IT892_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3168 domain-containing protein"
                     /protein_id="HAP3134506.1"
                     /translation="MREGTLYSLLSQLAGGQVYPYVVPLTEGKPAVSPPWLVFSVVSD
                     TVSDVLDGQAESRITVQIDVWATVPDDADNIREQALDAVRKLAPSVISKTQGYDPDSR
                     LSRATLEFQVIA"
     gene            complement(14942..15391)
                     /locus_tag="IT892_001273"
     CDS             complement(14942..15391)
                     /locus_tag="IT892_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAP3134507.1"
                     /translation="MMDFSLDFSGLADIARDLETLSRAENNKVLRDATRAGAEVMRDA
                     VVERAPERTGKLKKNVVVLTQRSKRRGEIISGVHIRGRNLRTGNSDNSMKASDPRNAF
                     YWRFVELGTINMPAHPFIRPAFDTTEELAAQVAIQRMNQAIDEVLSK"
     gene            complement(15388..15726)
                     /locus_tag="IT892_001274"
     CDS             complement(15388..15726)
                     /locus_tag="IT892_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001147815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAP3134508.1"
                     /translation="MQAGRLRDRVIILNVTTARSPSGHPVETVTEGATVWAEVKGISG
                     REIISGGAETAQATVRVWMRFRRDVTATSRLKVLTGAFKGAILGIEGPPIPDARATRL
                     EILCSLKGNV"
     gene            complement(15735..16052)
                     /locus_tag="IT892_001275"
     CDS             complement(15735..16052)
                     /locus_tag="IT892_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAP3134509.1"
                     /translation="MAAIVEKLRAQCRIDTDDATDDELLMLYFRAACRKAENFINRKL
                     YEETVPEGDPEGVLIADDVLLALMLLVGHWCENRENSSDVSKAPVPFGFSSLLEPYRF
                     IPL"
     gene            complement(16129..17346)
                     /locus_tag="IT892_001276"
     CDS             complement(16129..17346)
                     /locus_tag="IT892_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005288493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP3134510.1"
                     /translation="MKLHEMKQKRNTIAKDMRALHEKIGDNAWTDEQRAEWNRAKAEL
                     DALDEQIAREEELRRQDQAYVDESGPEERQNNEAENGKKAVEEKRAAAFNRFLRAGFA
                     ELNAEERNLMRELRAQSVTTDSQGGYTVPTQMRNKIIDTMKAYGGIASVAQLLTTSTG
                     QDITWSTSDGTTEEGELLAENTAATEQDVTFGTAILGAKKLSSKIIRVSNELLQDSGV
                     DIESYLANRIAQRIGRGEAKYLVQGTGTGSPLQPKGLAASVTGTIQTAASAAFTWKEM
                     NALKHAIDPAYRGGPKYRWAFNDATLQTIEEMEDGQKRPLWLPDIAGGTPATVLGIPY
                     VIDQAIDGIGTGKKFIFLGDFNRFIIRRVTYMELKRLVERYAEFDQVAFLAFHRFDCV
                     LEDVAAIKALTGK"
     gene            complement(17361..17960)
                     /locus_tag="IT892_001277"
     CDS             complement(17361..17960)
                     /locus_tag="IT892_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HAP3134511.1"
                     /translation="MNDRETRCYSGEVRAEQYDNAPTHILGYGSVFNSRSEPLWGFRE
                     IIKPGAFDDVLNDDVRGLFNHDPNFILGRSSAGTLSLSVDERGLRYDIVAPDTPTICD
                     LVLSPMLRGDINQSSFAFRVARDGESWYEDDEGIVIREITRISRLYDVSPVTYPAYQD
                     ADSGVRSMKAWQEARASGALKKAVNERMARERLLTLLNA"
     gene            complement(17953..19179)
                     /locus_tag="IT892_001278"
     CDS             complement(17953..19179)
                     /locus_tag="IT892_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000923127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP3134512.1"
                     /translation="MLLDALFRSESLENPSVPVTGEAAETDNIFARDVYVSPETSMKL
                     AAVYACIYVISSSVAQMPLHVMRKTNEHVQPARDHPLFWLVHDEPNAWQTSYKWRELK
                     QRHVLGWGNGYTWVKRNRRGEVTSLECCMPWETTLLNTGGRHTYGVYNEEGAFAVSPD
                     DMIHIRALGNNQKMGLSPIMQHAETIGMGMSGQQYTSAFFNGNARPAGIISVKNELNE
                     QSWGRLKNMWQRAVTALRSQENKTMLLPAQLDYRALTVSPVDAQIIDMTKLNRSMIAG
                     IFNVPAHMINDLEKATFSNITQQAIQFVRYTMMPWVANWEQELNRRLFTRTERAAGYY
                     VRFNLTGLLRGTPQERAQFYHFAITDGWMSRNEARAFEDMNPVDGLDEMLVSVNAANP
                     LNNFKDTKGKEEKNDE"
     gene            complement(19327..21084)
                     /locus_tag="IT892_001279"
     CDS             complement(19327..21084)
                     /locus_tag="IT892_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAP3134513.1"
                     /translation="MAKVADGIRYAERVVAGEIVAGEFVRLACQRFLDDLKYGEERGI
                     YFSEPRAQHILNFYKFVPHVKGALAGQPIELMDWHVFILINIFGFVIPLVNEETGEVV
                     MRSDGSGRPVMVRRFRTAYNEVARKNAKSTLSSGIGLYMTGADGEGGAEVYSAATTRD
                     QARIVFEDAKNMVRKARSTLGRLFDFNKLAIYQEQSASKFEPLSSDANNLDGLNIHCA
                     IIDELHAHKTRDVWDVLETATGARLQSLLFGITTAGFNKEGICYEQRDYAIKVLRGYN
                     SDVEGAVKDDSYFAIIYTLDEGDDPFDETVWQKANPGLGICKRWDDLRRLAKKAKEQV
                     SARVNFFTKHMNVWVTAESAWMDMIKWEKCEYIAPQHELKTYPMWVGVDLAHKIDICA
                     AAKLWRTDNGHVHADFKFWLPEGRLERCSRQQAELYRKWAEMDKLILTDGDVIDHAQI
                     KSDLLEWIGGENLRELGFDPWSAMQFSLALAEEGIPLVEVPQTVRNLSEAMKETESLV
                     YAGRFHHSNHPVMNWMMSNVTVKPDKNDNIFPNKSTPEAKIDGPVALFTAMSRFLVNG
                     GGVNDFLSTLDPDEDLLIL"
     gene            complement(21084..21566)
                     /locus_tag="IT892_001280"
     CDS             complement(21084..21566)
                     /locus_tag="IT892_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAP3134514.1"
                     /translation="MSGPPKTPPRLHLIRGNPSKRPVKDSKKTAKKDEKGLPKIPQHL
                     GAQGKYWFRRMAEELNAEGIISQLDARALELLVEAYTEYRHHCEILDVEGYTYRTETQ
                     NGDVLIKAHPAAAMKADAWKRIRAMLAEFGMSPASRAKVNTAGPDDVDPLAELLKARD
                     "
     gene            complement(21714..22064)
                     /locus_tag="IT892_001281"
     CDS             complement(21714..22064)
                     /locus_tag="IT892_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP3134515.1"
                     /translation="MPPRIPRACRKRGCAGTTTDSSGYCDKHRGEGWVQHQRGLSRHQ
                     RGYGSKWDAIRARILKRDNHLCQNCLRNGRAVEARTVDHIIPKAHGGTDADSNLQSLC
                     WPCHKAKTARERLN"
     gene            22590..22883
                     /gene="iss"
                     /locus_tag="IT892_001282"
     CDS             22590..22883
                     /gene="iss"
                     /locus_tag="IT892_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="increased serum survival lipoprotein Iss"
                     /protein_id="HAP3134516.1"
                     /translation="MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVS
                     GIGQEKTVDAAKICGGAENVVKTETQQTFVNGFLGFITLGIYTPLEARVYCSQ"
     gene            complement(22974..23156)
                     /locus_tag="IT892_001283"
     CDS             complement(22974..23156)
                     /locus_tag="IT892_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134517.1"
                     /translation="MRKLKMKLCALMLPLVVVGCTSKQSVSQCVKPPPPPAWIMQPAP
                     DWQTPLNGIISPSERG"
     gene            complement(23373..23906)
                     /locus_tag="IT892_001284"
     CDS             complement(23373..23906)
                     /locus_tag="IT892_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HAP3134518.1"
                     /translation="MNAKIRYGLSAAVLALIAVGAPAPDILDQFLDEKEGNHTTAYRD
                     GSGIWTICRGATMVDGKPVFPGMKLSKEKCDQVNAIERDKALAWVERNIKVLLTEPQK
                     AGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
                     VIRRDQESALACWGIEQ"
     gene            complement(23970..24320)
                     /locus_tag="IT892_001285"
     CDS             complement(23970..24320)
                     /locus_tag="IT892_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdfR family protein"
                     /protein_id="HAP3134519.1"
                     /translation="MTQNYELIVKGIRNFENKVTVTLALRDKKRFDGEIFDLDISLDR
                     VEGAALEFYEAAARMSIRQVFLDVAAGLCEGDEQSPEKRPVILEAQNVWITYKGKLPG
                     RITGSLKTPPESQP"
     gene            complement(24325..24540)
                     /locus_tag="IT892_001286"
     CDS             complement(24325..24540)
                     /locus_tag="IT892_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP3134520.1"
                     /translation="MDQMEKITTGVSYTTSAVGTGYWFLQLLDRVSPSQWAAIGVLGS
                     LLFGLLTYLTNLYFKIREDRRKAARGE"
     gene            complement(24690..24851)
                     /locus_tag="IT892_001287"
     CDS             complement(24690..24851)
                     /locus_tag="IT892_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134521.1"
                     /translation="MILRHRTGPAFQTIKDGLAVGLNALTLTDITKNATYGVEIESLV
                     LEINTPASS"
     gene            complement(24848..25036)
                     /locus_tag="IT892_001288"
     CDS             complement(24848..25036)
                     /locus_tag="IT892_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000874242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HAP3134522.1"
                     /translation="MAFKHYDVVRAAPPSDLAEKLTHKLKEGWQPFGSPVAITPYTLM
                     QAIAAEGDVVVSGATEPE"
     gene            25297..25632
                     /gene="iraM"
                     /locus_tag="IT892_001289"
     CDS             25297..25632
                     /gene="iraM"
                     /locus_tag="IT892_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HAP3134523.1"
                     /translation="MKWIVIDTVIQPSCGISFSVIWSKVKLIIWYQSDAFLPPESIFT
                     LTHTGIMLNNKVLPVTIYNVVPFNKTFWNLIKNSQECPTNTDNVLNECFNNRCILQIC
                     PYGLKQQSP"
     gene            25703..25915
                     /locus_tag="IT892_001290"
     CDS             25703..25915
                     /locus_tag="IT892_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001333559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134524.1"
                     /translation="MPLHGAGCLPVNSVPAPESAIIPYTYSLITPPHRGIHHAKFFNK
                     LPAGQTIIASLNYEQRGILRENCFLQ"
     gene            complement(26404..26490)
                     /locus_tag="IT892_001291"
     CDS             complement(26404..26490)
                     /locus_tag="IT892_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3927 domain-containing protein"
                     /protein_id="HAP3134525.1"
                     /translation="MVDFSSRIMSVLSDGVLVAGVWLLLSRC"
     gene            complement(26666..26741)
                     /locus_tag="IT892_001292"
     tRNA            complement(26666..26741)
                     /locus_tag="IT892_001292"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(26706..26708),aa:Ile,seq:cat)
     gene            complement(26885..27706)
                     /locus_tag="IT892_001293"
     CDS             complement(26885..27706)
                     /locus_tag="IT892_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HAP3134526.1"
                     /translation="MKLEDLPKYYSPKSPGLTDASASTSKDALSITDVMAAQGMTQNR
                     AEMGFSAFLGKMGISMNDRARATELLADYALSRCDRVAALRKLPAEIKPLVMRIMASY
                     AFEDYARSAASKKQCPCCYGEKFIESVVFTNKVQYPDGKPPVWAKCTKGVYSSYWEEW
                     KKVREVVKVACPECGGKGEVSTACKDCRGRGVAIHREESVKRGMPVIRDCQRCGGRGY
                     ERLPSTETFNAICEVTNQITRASWEKTVKKFYDALVTRFDIEEAWAERQLKKVTR"
     gene            complement(27703..28083)
                     /locus_tag="IT892_001294"
     CDS             complement(27703..28083)
                     /locus_tag="IT892_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAP3134527.1"
                     /translation="MTERIEFVLPYPPTVNTYWRRHGNTYFISEAGKRYRRDVALIVR
                     QQRLKLNLSGRLAIKVIAEPPDKRRRDLDNILKAPLDALTHAGVLMDDEQFDEINIVR
                     GQPVSGGRLGVKIYPIMHEEQVKK"
     gene            complement(28084..29142)
                     /locus_tag="IT892_001295"
     CDS             complement(28084..29142)
                     /locus_tag="IT892_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HAP3134528.1"
                     /translation="MRILLRPVLVPELGLVVLRPGRESMQVFHNPRVLVEPEPKSMRG
                     LPSGVVPAVRQPLAEDKSLLPFFSDDRVIRAAGGAGALSDWLLRHVKSCQWPHGDYHH
                     SETVIHRYGTGAMVLCWHCDNQLRDQTSESLGQLAHQNLSAWMIDVIRHAISGTQERE
                     LSLAELSWWAVCNQVADALPESVLCRSLGLPVEKIRSVYRESDIVPGEQTATSILKQR
                     TKNIALPLHVHQQQPPLQEKTLVSIAVDPESPVQYLQRQKPQREEMPVYTRWVKTQKC
                     MTCGNQADDPHHIIGHGLGGMGTKADDLFVIPLCRKCHNELHAGVKDFEEKHGSQLLL
                     LIRFLMHARNSGVLKWKA"
     gene            complement(29144..29422)
                     /locus_tag="IT892_001296"
     CDS             complement(29144..29422)
                     /locus_tag="IT892_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134529.1"
                     /translation="MAHDTKLHNSNDSAVFASRCGRRFHAFKSDWFQHPPCTEEQAEW
                     IIQCYRRRGYEVKKALSLDYRHWIISVRLPYSERPPRSSRTYQQRIWR"
     gene            complement(29590..29802)
                     /locus_tag="IT892_001297"
     CDS             complement(29590..29802)
                     /locus_tag="IT892_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HAP3134530.1"
                     /translation="MNGKSRLASYVPKGKEKQAMKQQKAMLIALIVICLTVIVTALVT
                     RKDLCEVRIRTGQTEVAVFTAYEPEE"
     gene            complement(30005..30223)
                     /locus_tag="IT892_001298"
     CDS             complement(30005..30223)
                     /locus_tag="IT892_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134531.1"
                     /translation="MFKCNCTLIVGGIMKNALQFLFVAFWLFVSCMPIIFTARYMEKV
                     DVLILIFGYINALFLGVFMAVMCIEYWR"
     gene            complement(30837..31019)
                     /locus_tag="IT892_001299"
     CDS             complement(30837..31019)
                     /locus_tag="IT892_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134532.1"
                     /translation="MRKFKIIIETGIAGGDFEDEFEVDDDATPDEIHDEAKDIFFNYC
                     NYSYHEIKDEEEEQNG"
     gene            complement(31113..31526)
                     /locus_tag="IT892_001300"
     CDS             complement(31113..31526)
                     /locus_tag="IT892_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134533.1"
                     /translation="MKLAIRLQLPLAFASKERSMEIKPEDELSNIVLFPVKEDDPRNQ
                     VNFLYEPSERPYCHHASVRVDEKERQVRCKICGAVVEPFDWMLSVAKRETRLADDVRL
                     LRQEERERRKNIEKLIQIERNAKARIRRATKSRTE"
     gene            complement(31527..31949)
                     /locus_tag="IT892_001301"
     CDS             complement(31527..31949)
                     /locus_tag="IT892_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HAP3134534.1"
                     /translation="MAKVFTQEEREKIKGQVLELVRQSGRETLRQLEAKTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSEQARKDWQNARKKLSRAKLKKPVVVDPDLIWSLPDG
                     EIRRYDSRLNIICRECRKSEAMQRVLAFYQGNFQEAVL"
     gene            complement(31990..33060)
                     /locus_tag="IT892_001302"
     CDS             complement(31990..33060)
                     /locus_tag="IT892_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001736248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer"
                     /protein_id="HAP3134535.1"
                     /translation="MANAWLRLWHDMPNDPKWRTIARVSGQPIATVMAVYIHLLVSAS
                     RNVTRGHIDVTTEDLASALDVTEEVIDSILQTMQGRVLDGDLITGWEKRQVLKEDNGN
                     ISQTAKSPAERKRAQRERERKREQNGDCHGESRNVTHMSRRVTTDKDTDKDTDQEDQN
                     TMVHGVKNATNQAGDVQTVTPGQPAGTTPEADSAYALKADSGAVQQVMTARQEQSHQL
                     QQPEADSAIQREADRVVPENTGQPVGRVDYPDVFEQVWREYPLRAGANPKKSAFSAWK
                     ARLREGVPPEAMLDGVRRYARYLAATGKTGTEFVQRATTFFGPDRNFENPWLLPVSGT
                     NNQRCVNHISEPDNEIPPGFRG"
     gene            complement(33132..33557)
                     /locus_tag="IT892_001303"
     CDS             complement(33132..33557)
                     /locus_tag="IT892_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HAP3134536.1"
                     /translation="MKIKHEHIRMAMNAWAHPDGEKVPAAKITKAYFELGMTFPELYD
                     DSHPEALARNTQKIFRWVEKDTPDAVEKIQALLPAIEKAMPPLLVARMRSHSSAYFRE
                     LVETRERLVRDADDFVAVAIAGFNQMNRGGPAGNAVAVH"
     gene            complement(33541..33783)
                     /locus_tag="IT892_001304"
     CDS             complement(33541..33783)
                     /locus_tag="IT892_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134537.1"
                     /translation="MKKSEVLGYFGGVVKTAAALGTSKTTVSMWGEEVPWKWALLIQA
                     VTAGALKYELHIPTVVIPGSDHNPPSNQGGIHENQA"
     gene            34175..34513
                     /locus_tag="IT892_001305"
     CDS             34175..34513
                     /locus_tag="IT892_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310236.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S24"
                     /protein_id="HAP3134538.1"
                     /translation="MKNSSITSCVQLVGEIPVNTFAVVLESDSMSTSGGGVSIPNGST
                     VFVDPDRTVQPGNIVLALPKGTTTPVIRKLEIEGPDILLVPTNPRYPSIMLDDLSCIL
                     GVCFKIQQDI"
     gene            complement(34945..35145)
                     /locus_tag="IT892_001306"
     CDS             complement(34945..35145)
                     /locus_tag="IT892_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310309.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134539.1"
                     /translation="MNTIKFSCPECGGEVFDTSFKPQGSDSFAGAICKNCGHLVTEDE
                     SSQFDDEIVDNIFGALTRDFLK"
     gene            35238..35456
                     /locus_tag="IT892_001307"
     CDS             35238..35456
                     /locus_tag="IT892_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134540.1"
                     /translation="MQKREPVIIAPDYTDDELYEWMRQKINAAQDLKWANEARAKQAE
                     NLSALEQDITRLEKAAALSIARMITYPR"
     gene            complement(35421..35624)
                     /locus_tag="IT892_001308"
     CDS             complement(35421..35624)
                     /locus_tag="IT892_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134541.1"
                     /translation="MNQLPRRALSRYGLTFQGNILSVNCQCRMLTRVRRTHSTSPVEN
                     SLITNLSFVGYLLTRVCNHSGNA"
     gene            36025..36213
                     /gene="dicB"
                     /locus_tag="IT892_001309"
                     /gene_synonym="ftsT"
     CDS             36025..36213
                     /gene="dicB"
                     /locus_tag="IT892_001309"
                     /gene_synonym="ftsT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibition protein DicB"
                     /protein_id="HAP3134542.1"
                     /translation="MKTLLPNVNTSEGCFEIGVTISNPVFTEDAINKRKHERELLNKV
                     CIVSMLARLRLMPKGCAQ"
     gene            36210..36401
                     /locus_tag="IT892_001310"
     CDS             36210..36401
                     /locus_tag="IT892_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1482 family protein"
                     /protein_id="HAP3134543.1"
                     /translation="MNPVFALILTVFLVSGEPVDIAVSVHRTMQECMAAATEQKIPGN
                     CYPVDKVIHQDNNEIPAGF"
     gene            36495..38936
                     /locus_tag="IT892_001311"
     CDS             36495..38936
                     /locus_tag="IT892_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAP3134544.1"
                     /translation="MSTDKEEFALYCEAKNDKVRKRLGIKGGFYWTTAKKLSVAISRC
                     ITAMDDNDYDEDDFKKPVRVNLPVVDDLPPEGVFDTEFCNRYEKGGKDGITMTFIGPS
                     PSVQDKPASTDNTNINGEAMTEIEESMLLPVSGQELPIRWLAQHGSEKPVTHVSRDEL
                     QALHIARAEELPAVTALAISHKTSLLDSLEIRDLHKLVRDTDKVFPNPGNSDLGLITA
                     FFEAYLDADYTDRGLLTKEWMKGNRVSRITRTASGANAGGGNKTDRNPNLVHTLDTLD
                     VEIAAATLPMDFNIYEIPGSVYRRAKEVVLNKESPFKEWSAALRATPGILDYSRAAIF
                     ALIRSAHPEFYHYPGRLQGYINAYLTETDHENPSKETLTAARHTPEKDILEEINREVV
                     TERETEEEKPQPSDAMAGEQATTETMEPDTTEHGQNAQSLDAQSQVSSANQVKVTADE
                     VNKIMQAANISQPDADKLLAVSRGEFVEGISDPNDPKWVKGIQTRDSVNQNQHESERN
                     DQKAEQNSPNALQNEPETKQSEPVAQQEVEKVCTACGQTGGGNCPDCGAVMGDATYQE
                     TFDEEYQVEVQEDDPEEMEGAEHPHKENTGGNQHHDSDNETGETADHSIKVNGHQEIT
                     STSRTCDHLMIDLETMGKNPDAPIISIGAIFFDPQTGDMGPEFSKTIDLETAGGVIDR
                     DTIKWWLKQSREAQSAIMTDEIPLDDALLQLREFIDENSGEFFVQVWGNGANFDNTIL
                     RRSYERQGIPCPWRYYNDRDVRTIVELGKAIDFDARTAIPFEGERHNALDDARYQAKY
                     VSVIWQKLIPSQADF"
     gene            38998..39267
                     /locus_tag="IT892_001312"
     CDS             38998..39267
                     /locus_tag="IT892_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAP3134545.1"
                     /translation="MSEQYLITLDEWKPKRFSLPITNTTLVKYGKLGYIVPRPQKIRG
                     RWLIDRRAVFVGPGETGIAPEIHTGDDDALKEILTHVTEATKKQH"
     gene            39236..40354
                     /locus_tag="IT892_001313"
     CDS             39236..40354
                     /locus_tag="IT892_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP3134546.1"
                     /translation="MSPRPRKNSTDVAGLYEKFDRRTGRVYYQYKNPVTGKFHGLGTD
                     KGKAEKIASTANQRIAAAEAEYFMRKIDESLSATKRRGIRLKAWVDRYLKIQDTRLKN
                     GDIAATTHKEKTRMAAYLVSRLGNHPLKELEVRDFALILDEWLDKDMVSTARVNRGLW
                     VDIYKEAQHAGEVPPGWNPPEATRKPIPKVTRARLTMEDWQKIYNATPEKHFIRNAML
                     LAIVTGQRRDDICHMRFSDVWNEHLHITQGKTGMRLALPLTLRCDAIGITLKEVIDGC
                     RDRILSPYLIHSRHQKQPKPMSKDNLSDYFAKARDLAGIIPPAGKTPPTFHEQRSLSE
                     RLYRAQGIDTKTLLGHKVQATTDRYNDTRGQEWVKLVI"
     gene            40521..41315
                     /gene="potC"
                     /locus_tag="IT892_001314"
     CDS             40521..41315
                     /gene="potC"
                     /locus_tag="IT892_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotC"
                     /protein_id="HAP3134547.1"
                     /translation="MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTT
                     KWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFV
                     VMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
                     AAKDLGASEFTILRKIILPLAIPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKI
                     YSMVKVGVSPEVNALATILLVLSLVMVIASQLIARDKTKGNTGDVK"
     gene            41312..42358
                     /gene="potD"
                     /locus_tag="IT892_001315"
     CDS             41312..42358
                     /gene="potD"
                     /locus_tag="IT892_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /protein_id="HAP3134548.1"
                     /translation="MKKWSRHLLAAGALALGMSAAHADDNNTLYFYNWTEYVPPGLLE
                     QFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKS
                     KLTNFSNLDPDMLNKPFDPNNDYSIPYIWGATAIGVNGDAVDPKSVTSWADLWKPEYK
                     GSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPANPY
                     MEGEVNLGMIWNGSAFVARQAGTPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLIN
                     FLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLYPDAETIKNGEWQNDVGAAS
                     SIYEEYYQKLKAGR"
     gene            42416..42877
                     /locus_tag="IT892_001316"
     CDS             42416..42877
                     /locus_tag="IT892_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3592 domain-containing protein"
                     /protein_id="HAP3134549.1"
                     /translation="MSQDSKVFFRIFLGIGLVLILISVVVFYNQFTYSKDAIHTEGVI
                     VDTVWHSSHSHRTGKDGSWYPVVAFRPTPDYTLIFNSSIGSDFYEDSEGDKVNVYYSP
                     GHPEKAEINNPWVNFFKWGFIGIMGVIFIAVGLLISMPSSKKSRRKRKSRP"
     gene            42874..43662
                     /locus_tag="IT892_001317"
     CDS             42874..43662
                     /locus_tag="IT892_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAP3134550.1"
                     /translation="MKKFIILLSLLILLPLTAASKPLIPIMKTLFTDVTGTVPDAEEI
                     AHKAELFRQQTGIAPFIVVLPDINNEASLRQNGKAMLAHASSSLSDVKGSVLLLFTTR
                     EPRLIMITNGQVESGLDDKHLGLLIENHTLAYLNADLWYQGINNALAVLQAQILKQST
                     PPLTYYPHPGQQHENAPPGSTNTLGFIAWAATFILFSRIFYYTTRFIYALKFAVAMTI
                     ANMGYQALCLYIDNSFAITRISPLWAGLIGVCTFIAALLLTSKR"
     gene            complement(43782..44621)
                     /gene="cobB"
                     /locus_tag="IT892_001318"
     CDS             complement(43782..44621)
                     /gene="cobB"
                     /locus_tag="IT892_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415638.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAP3134551.1"
                     /translation="MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVL
                     VLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQP
                     EIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQ
                     VLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDAIYMALSMADIFIAIGTSGH
                     VYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGLKAG
                     SIA"
     gene            complement(44637..45548)
                     /gene="nagK"
                     /locus_tag="IT892_001319"
     CDS             complement(44637..45548)
                     /gene="nagK"
                     /locus_tag="IT892_001319"
                     /EC_number="2.7.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HAP3134552.1"
                     /translation="MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVC
                     ELVAEADQRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRL
                     DNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRL
                     PVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQG
                     DEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLADRLPRHLLPV
                     ARVPRIERARHGDAGGMRGAAFLHLTD"
     gene            complement(45577..46821)
                     /gene="lolE"
                     /locus_tag="IT892_001320"
     CDS             complement(45577..46821)
                     /gene="lolE"
                     /locus_tag="IT892_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolE"
                     /protein_id="HAP3134553.1"
                     /translation="MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVG
                     LSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDHVQKVPGIAAAAPYINFTG
                     LVESGANLRAIQVKGVNPQQEQRLSALPSFVQGDAWRNFKAGEQQIIIGKGVADALKV
                     KQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMG
                     SSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAM
                     VLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCG
                     VIIGVVVSLQLTPIIEWIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSL
                     LASWYPARRASNIDPARVLSGQ"
     gene            complement(46821..47522)
                     /gene="lolD"
                     /locus_tag="IT892_001321"
     CDS             complement(46821..47522)
                     /gene="lolD"
                     /locus_tag="IT892_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415635.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HAP3134554.1"
                     /translation="MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSS
                     GSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDF
                     TALENVAMPLLIGKKKPAEINSRALEMLKAVGLDHRANHRPSELSGGERQRVAIARAL
                     VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM
                     RDGRLTAELSLMGAE"
     gene            complement(47515..48714)
                     /gene="lolC"
                     /locus_tag="IT892_001322"
     CDS             complement(47515..48714)
                     /gene="lolC"
                     /locus_tag="IT892_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolC"
                     /protein_id="HAP3134555.1"
                     /translation="MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTV
                     LSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVV
                     LQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGD
                     QIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGN
                     ITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVA
                     VAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGA
                     LLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQP
                     AEALRYE"
     gene            48976..50049
                     /locus_tag="IT892_001323"
     CDS             48976..50049
                     /locus_tag="IT892_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HAP3134556.1"
                     /translation="MKQKELWINQIKGLCICLVVIYHSVITFYPHLTTFQHPLSEVLS
                     KCWIYFNLYLAPFRMPVFFFISGYLIRRYIDSVPWGNCLDKRIWNIFWVLALWGVVQW
                     LALSALNQWLAPERDLSNASNAAYADSTGEFLHGMITASNSLWYLYALIVYFVVCKIF
                     SRLALPLFALFVLLSVAVNFVPTPWWGMNSVIRNLPYYSLGAWFGATIMTCVKEVPLR
                     RHLLMASLLTVLAVGAWLFTISLLLSLVSIVVIMKLFYQYEQRFGMRSTSLLNVIGSN
                     TIAIYTTHRILVEIFSLTLLAQMNAARWSPQVELTLLLVYPFVSLFICTVAGLLVRKL
                     SQRAFSDLLFSPPSLPAAVSYSR"
     gene            50177..53623
                     /gene="mfd"
                     /locus_tag="IT892_001324"
     CDS             50177..53623
                     /gene="mfd"
                     /locus_tag="IT892_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAP3134557.1"
                     /translation="MPEQYRYTLPVKAGEQRLLGELTGAACATLVAEIAERHAGPVVL
                     IAPDMQNALRLHDEISQFTDQMVMNLADWETLPYDSFSPHQDIISSRLSTLYQLPTMQ
                     RGVLIVPVNTLMQRVCPHSFLHGHALVMKKGQRLSRDALRTQLDSAGYRHVDQVMEHG
                     EYATRGALLDLFPMGSELPYRLDFFDDEIDSLRVFDVDSQRTLEEVEAINLLPAHEFP
                     TDKAAIELFRSQWRDTFEVKRDPEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYF
                     PANTLLVNTGDLETSAERFQADTLARFENRGVDPMRPLLPPQSLWLRVDELFSELKNW
                     PRVQLKTEHLPTKAANANLGFQKLPDLAVQAQQKAPLDALRKFLETFDGPVVFSVESE
                     GRREALGELLARIKIAPQRIMRLDEASDRGRYLMIGAAEHGFVDTVRNLALICESDLL
                     GERVARRRQDSRRTINPDTLIRNLAELHIGQPVVHLEHGVGRYAGMTTLEAGGITGEY
                     LMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWSRARQKAAEKVRDVAA
                     ELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
                     LVCGDVGFGKTEVAMRAAFLAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEM
                     ISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKFKDLGLLIVDEEHRFGVRHKE
                     RIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSMVV
                     REAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMND
                     FHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWL
                     LTPHPKAMTTDAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGF
                     SLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRI
                     ASAKTENELEEIKVELIDRFGLLPDPARTLLDIARLRQQAQKLGIRKLEGNEKGGVIE
                     FAEKNHVNPAWLIGLLQKQPQHYRLDGPTRLKFIQDLSERKTRIEWVRQFMRELEENA
                     IA"
     gene            53767..54729
                     /gene="ldtC"
                     /locus_tag="IT892_001325"
     CDS             53767..54729
                     /gene="ldtC"
                     /locus_tag="IT892_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtC"
                     /protein_id="HAP3134558.1"
                     /translation="MMIKTRFSRWLTFFTFAAAVALALPAKANTWPLPPAGSRLVGEN
                     KFHVVENDGGSLEAIAKKYNVGFLALLQANPGVDPYVPRAGSVLTIPLQTLLPDAPRE
                     GIVINIAELRLYYYPPGKNSVTVYPIGIGQLGGDTLTPTMVTTVSDKRANPTWTPTAN
                     IRARYKAQGIELPAVVPAGPDNPMGHHAIRLAAYGGVYLLHGTNADFGIGMRVSSGCI
                     RLRDDDIKTLFSQVTPGTKVNIINTPIKVSAEPNGARLVEVHQPLSEKIDDDPQLLPI
                     TLNSAMQSFKDAAQTDAEVMQHVMDVRSGMPVDVRRHQVSPQTL"
     gene            complement(54811..55068)
                     /gene="bhsA"
                     /locus_tag="IT892_001326"
     CDS             complement(54811..55068)
                     /gene="bhsA"
                     /locus_tag="IT892_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple stress resistance protein BhsA"
                     /protein_id="HAP3134559.1"
                     /translation="MKNVKTLIAAAILSSMSFASFAAVEVQSTPEGQQKVGTISANAG
                     TNLGSLEEQLAQKADEMGAKSFRITSVTGPNTLHGTAVIYK"
BASE COUNT        13430 a        15076 c        12893 g        13723 t
ORIGIN      
        1 ttgcccgtct gttgtttttt gcgcataaaa cagatacgca gcagacgttc caacctcaaa
       61 aacgttttgt cgagtactgg aaccccacac cctgatacta actggtagtt ctgaattacc
      121 tgaattaagt aaagcaaaac gattgccagt ccctgtttgt tttctaatta ctaaatcggc
      181 agttgagtta acctcatctt tgttgatggt tagcgcctgc gctgtagcac cgttaacagt
      241 gccacttagt agttgaaccg ctccatcatc gccatttaac agcacttgag cgctgcttct
      301 gtggtttttc aggaacaaca ttttgcctgt gctttctgat gtgcctaccg accacgccga
      361 attggttcca gtgctatcaa caccgcgcac agcacaattc atactactgt aatctgacgt
      421 actccccagc acatcaacac gcccgccgcc taattttgat ggagtcgtcg aggttaacga
      481 cctgacggtt acatcctgat tccatcctga aacaactacc tgactccact ccgtccagtt
      541 tccattgaca acaaagcgaa cgtatatgcg ttttgtgtcg ctgccaatca gcgtttgcat
      601 gatcgcataa tctgaacccg tagttttacg agtagattct acacgtagca aaaagttacc
      661 gcttacgccg tcaggcttat tggtaatata tgcaccacct gcaacagttt tgcattgata
      721 gtatttaaca gatccagcca ctgtattagc aatgatcaag tcgtttaaat caatagtctt
      781 gttgtcaatg gtttccggct cgatagatcc cgccatacct gcgttaaatg tggcaaagtc
      841 agaaaaggtt gttttaccgc ctaccgtcac cccgctatcg agttttgctt gtgtgattac
      901 tttgctgttt tttgtgtggt cagaataact accaaaatac aaatcaccgt caccagctat
      961 acccaggtat ttttgatcaa catcatcaac cttaaaccca atggacaagt ttttaattgt
     1021 gttgttgctc gttaaaacca aaggcgtatg ctgagatcct ttgatgctta ccgtagtgtt
     1081 atcggaactg gtgcttgtgt ttgcaaattc tgcggtggct gcgctgattt tgtaagttat
     1141 ttttagattg cgggcctcaa ccctcccgtc gtggcgaaca ataaaatcac cacttgattc
     1201 accttttgtg tttttcgccc tgatgtggat ttcgccaagt gattcgttgt tttcaggcga
     1261 ccaaacaacg ccgcgctcgc ttccgtcgtt gttcatgaac cacagatgag cggttccttt
     1321 tgctgatttt agcctgatag atggcgtttc tttcaatata tcaagatcac cagacataac
     1381 atcgccggat tttttcacct gcgcatcgtt agttacgttg ccaagtccaa catccgattt
     1441 cgacggcttg tttgccgagc cgtatagctc attgatgcta aaagtcccgt tgttaagccg
     1501 ggcatcgttg ccggcataga tcttaatctt cgcggttgag tagtcgatat tgatcgctga
     1561 ccacgtatcg ccgcaccgcg agaatatacc agaaccgtgg ctataaatgg tcgccgtgct
     1621 tccggtcggc ttatcaccgc gccagaaatg accacctttg tcacgcagag cttttaagat
     1681 ctctacatcg ctcatcttgc cgtttgttga tatcccgcta ccgccaagac cgaaagcgcc
     1741 tgtaagcata gcattagaaa gacccaaatc tgctttagtc ggcttgttta actggtcgta
     1801 aatccttaca acggggcttt caacatatcc agaaggcgcg gcggtttgct taacaaatcc
     1861 gtctggaatg tataattccg ggcgtgccgt ctgcgccagc accgcaacct ttgcgccgtt
     1921 gataaatgcg cgctggaagg cccaaacctc aataaagccg tcacctttaa ccaggccgta
     1981 acgcatctgg ttgttatcgg tcagcccggt tgaccctaag cggcgtatac tcagatgacg
     2041 agaaacatta tccgcactaa gcaaagaagg cagaccgcgc gccgagatct cgataaagtc
     2101 aatgtttccg taaggggagc cgtagttacc ggcattagta accattagcg ttacatggca
     2161 attgccgctt ccgggatcgg aaagtttcgc gatctttatg taaaaagact cattaccagt
     2221 aacaacgggc caatcgtatt gcgtcatcgg gctgacgagt cccccgacct tgtcgagata
     2281 ttctttcgcc ttgttctctg acgctttagc gttggtttcg ctgacctttg ctgctgcctc
     2341 actatttttc gcgttggttt ctgatttttt ggctgctgtc gcggagtttg ccgatgcagt
     2401 ttgtgagtct gctgccgcct gtgcgctgtt atccgcattc gtctcagacg tttttgcggc
     2461 cttcgcggaa tttcctgctg ccgttgccga ggaagctgca ctgccggcgc tcgaggcagc
     2521 gctcgtttct gatgattttg ccgccacttt tgaagccgac gcatcccggg ctgaggtggc
     2581 agcttctgac gctttcgtgg tcgcggtgga tgcagatgtg gccgcagatt tttgtgatgc
     2641 tgcggcattc atttccgacg ttttcgctgc accggcactg gtggctgccg cgctttttga
     2701 agactctgcg gcggcagcac tttttgatgc ttcagtggcc tttgttgatg ccgttcctgc
     2761 gctggaagac gctgactgag ccgacgacgc ggcctgtccg gctgacgtgc tggctgcacg
     2821 tgctgagcct gcagcatcag tcgcacgggt tgccgcctca cgggctgatg tgctggcatc
     2881 gctggctgac ttcttcgcgg ctgccgtgtt ctgtgccacc gcggacgcgt tacgcgccac
     2941 ctcttccacc atcagttcaa aacggcgcag tgcctcagga cgggcatcat cctccgtcat
     3001 ggcaccgaga aaatcattca gcgtaccggg tcgggaatct tcatacacgg tgatggtccc
     3061 ggcatgtgac ggcgggaatc cttccaccaa cagaataacg ctgtactgac cgtactcaac
     3121 gtccatgctg taacgcccgg cttcatccgg attttctgag gccagcgtgt tcaccaccac
     3181 cgtggtactg ttacgttttg ctttcagctg gattgtgcag ttctgtaccg gttttcctgt
     3241 gccgtctttc agtacacctg aaatctttac tgccatattc accccacaaa aaagcccgcc
     3301 tgaaccggcg ggctgtcata acactgtgtt acctggctaa tcagaattta taaccgacac
     3361 ccacgatgaa accgtcagtg cgccagtcgc cactgccgga accttcataa gcgacatcaa
     3421 cggccacgga ttcggtcggg ttaaactgca cgccagcccc ccacgccaga gacgtgttgc
     3481 tgtggcgacc gtcatcactt ccggtcagca cgtcgtgcgt tttccccttg ttgtcagtta
     3541 cgcggagata atccccggag aaagtcgaca cacggctgta agccataccc gccatcgcat
     3601 acgcgctgaa ccattcattc acgcgcacag acggccccgc catcacgctg aaccagcggt
     3661 tacgcacgga atcttcatgc cagcgggtat cgctgtaatg cgttttttgc tcatctttgg
     3721 cattggcata actgaatgac gtcaccagcc ccagcgtgtc cgtaaattca taacggtatt
     3781 tcacgttaat cccgttcaga ttatcgctgc cggggacgtt cgtacgggca tgaagatacc
     3841 ctgcgctcag tgtggactgg tgttcagacg cccatgcagg cgtacctgat acggccagac
     3901 agatggctgc ggacaaaata gctgcataaa ctttacgcat aattacctct cgcttttctg
     3961 caataaaaaa ggcgccattt ctggcgcccg tatctgggtt ataaaattca gctaatcgtg
     4021 atgcctgcag tggctttctt catcaccaca accagcaaat cgctgatact ggctgtggga
     4081 taccagttat ttaccagcca tgctgacacc gaaaactcca gtgtcatgtg accgtgaccg
     4141 gcaggcatat caataacacc actgtaaatc agcgtattat ccagcgcggt acggttataa
     4201 atttcagcac cgtttttccg tactatcagg cggcatgacg aataaatatc gttattctcc
     4261 cgctcatgtt tagcgccgct gaatgccacc gccggaataa caatctgccg gtcaaacggc
     4321 tgatcgtcat aaaccctgac ggtgatggtc cctgatggcc accgttccgg tgcacgggag
     4381 tcccggggga aagctttgcc cactgtttta acgagatcgc cttcaatctg gttggcggac
     4441 agttttccca gaacccgaca gttctcgtta atcgtgacgt tgttgagcgt cccggcgttc
     4501 gcattcacgt taccgctgat atcggcattt ttcgccgtca gccgcccgtc cggtgtcagg
     4561 gaaaataccg gaggattacc gccgctggta atggtgggag ccgtcaggcg tttcaggaac
     4621 acttcgttca tgaatatctg atcgccctgc ccaacaaaca tcggctttgt gttgccattc
     4681 gcaggattaa tcatcgcaat cctgtctgcc gccagcagca cctgactctg catgccgtca
     4741 ggggtgttct caataccggc accaataccc gcgatataaa ggcgtccgtc ctgcatctgc
     4801 tgcagcttca cagcccacat gctgttcagg ttattatttg tatcaacctg aaccttctgt
     4861 atctgctgaa ttgccgcact ctggtcttcc agtttcttat tgacggtctg cgtgatttca
     4921 ttgctgacat ccgtaatgga cgtcctgatt tcagccaggt caggcgcaag ctgaccgtta
     4981 tcaatctgcg tccacagctc ctgagccaga tgggttttcc ctatctcgcc tttgaaaaaa
     5041 tccagataac cggatgcatc atcactcggc tgaccaacag cctccacgaa tgccgatttg
     5101 ccaacggtgt tcacactgcg gatataaaag taataatcat ggcccggttt gatattgata
     5161 ctggcggcta tccagtacag cgccgtgcca agatagcgtg ctgtggtttc aacctgcctg
     5221 atatcggtaa tccgcttttc cgagaaccag aactcaaact gtaccgtcgg atcataaacc
     5281 gcaagatgcg gcgtggcggt tatctgaaaa tagcccggcg tcagctcaat ccgcgacggc
     5341 gctgccggtg cggcaatccg gaacgatacc gacgccggat cgccctgctg cccccacgca
     5401 tttactgccc ggactgtcag cctgtagttc cccagcgcca gttgtgtgaa gcggtaagtg
     5461 gtttccgtcg tccgggccgt gctgaccagc cactcactgc cgtcatccgc tgttacggtc
     5521 agacggagca ggaagctcac gcccttcacc accttcggcg tgtcccagcg cgccagcacc
     5581 tgatattccc cgctgtctgc ggtgacttcg gcagtcaggt gctgcaccgc tggcggcgtg
     5641 acaccattca ccgtgccgct ctggtcgccg tcaaagtgcg ccccgttatc cacgatggct
     5701 tctttttccg gtacatgctg cacggcggtg atggcatacg tgccgtcatc gttctcacgg
     5761 atactcacac agcggaacag gcgctggcgc agcgtcggca acttcagccc ccacacgctg
     5821 tattctgcaa caccatcagg aacccggctc actttcacct tcacgccgtc ggtgacggac
     5881 tggacctcca cgctgaccgg attaccctga ccgtcaacca ggcttatcag cgtggtaccg
     5941 gaggatggca gcgtgatttc acggtcgagc gtcagcgtcc gggtctggct gttcaccgcc
     6001 agcacgcgcc cgccggtgct gatacccgca tagtcatcat cgcagatttc aatgacatcc
     6061 cccggtacat ggcgaagccc ttccgcaccc acgctgaagt ccacggtctg cgtttccagc
     6121 agttccgttt taatcagcca cagcccggcg cggtgcgcct gcccccggct ggtacagcca
     6181 aaggcatcca tcttcgtgac gttacgaccg taacgggcaa tggcctgcgt atcttcaaca
     6241 agctctgtcg ccgtctccca gccgttgtcc gggtcaatcc agttcacctc aacggcatta
     6301 tggcggtctt tcagggcgct gaagctgtag cggaacggcg cgccatcatc cggcatcacc
     6361 acattactgc ggttataggt ccacacctta tctgatggtc ggtcctgcac gaacgtcagc
     6421 gtctgcccgt tccataccgg catacagcgc atcgccgagc agaaatcact gagcacatcc
     6481 cacgccttgc gctgtgtggt caggtacgca ttacaggtga tgcgcggctc cgtgccgcca
     6541 aagccgtccg gcaccgactg gtcgcagtac tggccgatga catacagcgc ccatttatcc
     6601 acatccgccg caccaagacg tttccccatg ccgtagcgcg gatgggtcag catatcccac
     6661 agacaccagg ccatgttgtt gctgtatgcc ggtttaaacg ttccgtccca gataccgctg
     6721 tattgccgcg tctgcgggtt atagttcgac ggcacctgca gaatgcgccc gcgcagatga
     6781 taattacggc tcacctgctg gctgccgaac tgctccgaat ccacctgtac gccgaccagt
     6841 gccgtgttcg ggtagcactg tttcacatcg atgatttcgg tgtatgacga ccagagcgtt
     6901 ttgttctgca gctggtctgt ggtgctgtcc ggcgtcatcc tgcgcatccg gatattaaac
     6961 gggcgcggcg gcaggttatc caccaccacc gaggccagat actgcgaggt ggttttgccc
     7021 ttaatggtga tgtctttttc cgtcacccag ccaccattac gctgtatctg aaccagcagg
     7081 cgaacttccg acggattccg gtcccccttt gaggtggttt ccaccagtgc ctgcacaccg
     7141 aaggtaaagc gcagacggtc gatgtttgca gacgtgatgg tgcgggtgat cggcgtgtca
     7201 tatttcactt ccgtacccag caccgtctcg gagccggagg attcaaaccc ctccggcggt
     7261 gtctgctcct gctcaccggc acggaacacc accgtgacac cggagatgtt ggtattcccc
     7321 tcagtgtcca gcaccggcgt actgttcagc agcacgcttt ttaatccatc caccggacct
     7381 tcaaccggcc cttcactgat ggcgtctatc acgctcagca tctgggatga tttcaggttg
     7441 tccttcgctt cgcgcggggt atgcccctta ctgctgcctt tacccattcc tcacgctcca
     7501 gaaacgacaa aaccgccctg aggcggtttc acataaaacg ttttgcatca gcgaccaatc
     7561 accacaacct gaccaccgtc cccttcgtct gccgtgctga tctcctgaga agccacccgc
     7621 gaccccacgc gcatttcacc gtacagaacg ggcagaacat tgccctgggc aaccatgtta
     7681 tccagtgagg agaaataggt gttctgctta ccgttatccg ttgtctgtgt acggggagtt
     7741 ctggctttcg gtgccagcat ctgcgccaca ccgccaagga tcatactggc ccccgcagca
     7801 tacatgcccg atacagccgc agctcccagc cagcccacag ggttccacca cgccactgca
     7861 atcagcgccg cacccagcac cgcctgaaac acaccgccac tttttgctcc cgcaagacgc
     7921 ggaacgatgt ggatcacggc accatttttc agcggctcat taagacgggc tgataattcg
     7981 ttttcgcctg catcacgccc ggcaatgcgc acctgatacc agccatcgct cagtttctga
     8041 cgaaacgccg ggatctgcat ggccagcgcc cggatggctt cggcccccgt tttcacacga
     8101 aggtcgatgc ggcggccaaa tcgttgcaaa tccccgtaaa ggcagatacg tgccatgccc
     8161 ggtgacgcca gagggagtgt gtgcgtcgct gccatttgtc ggtgtacctc tctcgtttgc
     8221 tcagttgttc aggaatatgg tgcagcagct cgccgtcgcc gcagtaaatt gcggcgtgat
     8281 tcggcaccga tgaaccaaaa cagcacagca gcacatcgcc cggctgtgcc gctgacaacg
     8341 gcacctgata cagccccgtc gcctccagat tatccagata gagattctgg ccgttacgcc
     8401 accagtcatc ctcacgatga aaatcaggca tctcaattcc cgccagatgg taagcatccc
     8461 ggagcagcgt gtaacagtcc gtcaccccgt gctcaaagcg ccgcccggta agatgcggca
     8521 cacagcggaa cttgtgaatc gccccccggc agaccagcca ccacggcaaa tcactctgca
     8581 cctgcagccg ccggtcggcc tcactcagcc agggcagacc accggggtgg ctgtggacca
     8641 gcgccacaat ctcaccctgc atttctgcct gcagccagtc ttccggcgac atacggaaat
     8701 acgcctccgg ctcaccggag atattcacgc agggaaaata tctttccccc tccggcgtgc
     8761 ttaccacgaa gccgcacgac tccgctggcg cacatcgccg ggcgtgcgcc agaatcgctg
     8821 attctgtctg tgtcatggga tttactgcga aagtttgtta atggaaagga agccgccaaa
     8881 gttgccgacg ttattgcgga acttacaacc gctcaggcat ttgctgcatt tatccttcgt
     8941 gatatcggac gttggctggt catattcatc cgcgacagcc ggaccgctat aaccgcactc
     9001 gtcaccgcga taggtccagg tgcaggtgtt ggccagcatg atacgtcccg gaaaaacagc
     9061 gccatccgtt tccgtcggcg tggacagtac aaaggaggca ctcaccgcgc tcagttcgct
     9121 gcactgctca atgcgccagc ggctgatcac ctcctgctcc ggatcggcgt aactgtttcc
     9181 gttgacgaag ttcaccgcat ccagaaaacg ggcgtaaacc ttacgccgga ccaccgttcc
     9241 gccgaccaga ctctgcatat cttccgccat cccggtgacc atgccgtaca gattagagac
     9301 tttaagcgtt ggccttgcac tggctccttt gccgttcatc tcaaatccgc ttccctgaat
     9361 gggataagcc tgatactgcc gcccctgcca ggtgactggt tcaccttttt cgttctgctc
     9421 attacagaag aaataacgat ctccgccgac ctctgtcaga tcaatttccc agagcacgac
     9481 cagcgcggat tgctccgttt tagtgcactc attgagtgtt tcctgctgta tatcctgcat
     9541 cagtgagtga cctcttcaaa ggtacagtta aaatcggtat acatggcatt atccgaaatg
     9601 ctccactccc tgcagacaac ccggacagtc ctgttgtgtt ttggcggacg ccacaaaaaa
     9661 gcacgaatcc cggcatgacg ggataaaaaa ctgtccagcg cggcacggga atattcatct
     9721 gtgacacgaa ataccggttt aaacgttttc agatccgcat tcagaccacc agcccgtcgc
     9781 tgttcatatc cgtcaccaaa ctttaccgta ataactgatg gctttcgtgt cgtctccatc
     9841 ccctcacggg ggatccagtt aaaaacttca ggctcaggca ctgtacaatc ctccatcccg
     9901 acgcgatgac tgcataattg acacaaccct gctgtcgatc agatccacca gtcccctggc
     9961 tgagcgcgca tctatctcgc cattgctccc ttgattctga atgctgatgt gatacacggg
    10021 agaataaaca aatccaccgc caccattcac atctccaatg gccctgaccc caagagagcc
    10081 gtccgctgcc cgtgtcagtg gcatgattgc ttcaggcccg gcctcgccca tcaacccggc
    10141 ccccttcgca aaagcaaaat acgtcggtgt atccacaata gtgttactgt aagcactcag
    10201 atttgccgat gtgtaaacac caccttttgc gtttgccact gcccccgaaa tccatccgcc
    10261 gaccgtacca agccaccctc cggcaccgga gagtgatttc agtccgttaa caatggctgc
    10321 attcatcaga atttttgaaa cttcccggag aactgaactc ccccagttcc tccagtccac
    10381 aacatttccg gccagtgcat cggaaatatt tgataccagc ccgtccatag tggaaacgac
    10441 agcatctgcc gcctgcgaag cataatcggt ggcactgtct gcccagttgg tcagcccctc
    10501 ctggagtcct gcattccagt tattacgtaa agcatcggcc tttgcataat aatcctgctg
    10561 atcgctgaga cgctcttcca gatatttttt attcagttct ttctcctgtt tccacagggc
    10621 ttcttcaatt tctccggcct gatactgtct cagcagctcg ttatttttct gctcaaactc
    10681 atgccggata ctccacattt cctggagtcg ttcacgcatc cgtgagcctt caccatatcc
    10741 cagtaactgc gcgtcgttag acgcccgggt actggcatta ctgtccgcca ggctgctttc
    10801 atacgcagca agctgctcac gaatcttttt ctggtcgatg agtgctgcat tctgcaaaag
    10861 cgtttttttc tgcgcttctg acagggttga taattcgccc tgactgacct gatatttcat
    10921 cttagccagt tcagtattct gccctgccag tgctatctgt tctttttgct gtttaatcag
    10981 ccgtttataa atatcttctg ttttttccgc ttcggtcttt ttatgcgctt tgggtttatt
    11041 tgcctggtta tttcgccagg catccagtga gttattgata taattctgtc tggctgtctg
    11101 atacgcctct cccacaaagc caagatcatc cgcagcatag cccagtcgag cacgctcacg
    11161 cgcttccccc ttaaggcggg acagagccag ttcgcgcttg ctgttattca gtgcggtctg
    11221 ctgtttatca tccagggttg cctgtggtag ccgtaacggt acattcacca acccctgtcg
    11281 ctgctgaagt aattcattac caagcccaag aaggcgatta aactcggtat gctgcccatt
    11341 catgatcaac agggactgat acgctttgtt ttgttccgcc gcctgttgac ggatcaacgc
    11401 aacccgccgc tcctccagcc cggcaagcac atcctgaatg gattgcgctt tgccctgcat
    11461 ttgtgtgaga cgggactgtt caactgccag ttgatttgtt gcttctgcaa gcccttctgt
    11521 gactgttttt accgacgtca tgtggttaat cataaaaccg ttatcggttg tccagcccgg
    11581 gtttgccagc acatactgat agccagcaat tttttcctgt aaggatttaa tcttactttt
    11641 ctgctcgtca attaacctgt tttgctcatc aagtgcctgc cgcgtctttt cctcattatc
    11701 tgacgcttca ggaagcgaca ttgccgacgt tttctggcga atttcgtcga ttgttgcggc
    11761 atactggcgt gcagattctc tggcctgctc ctgattctga tacatcgtgt accaggccgt
    11821 cgcccccagc atgacgagtc ccggcacacc accaaccagc cccagcgcac cacttaacag
    11881 acgactcccc actgacgtga cagtattcag cgttgtctgc gccgctgttc tggccgcaat
    11941 attacgggta agtgacgcct gagcagctgt cagcttcgct tctgctgcgg cctgcctttc
    12001 ggtaccgcga gcagcaacaa ccgcctgttg cgcacgataa accgccgcac gcgctctggc
    12061 ggttgctatc tgtgtccccc gaagttgcgc ttcagcaaga gccacttcgt ttctggctgc
    12121 agtaattaat ccggcagttg cagatccagc agacgacgcc atattgccaa aatatcgggc
    12181 taccccgacg gcaaccagtg cgccagctgc agcagccacg gtatcaatat tgtctgcaac
    12241 accattcagc acaccggaga gtgtctttgt cactccgctt gcctcgttcg caccaccaac
    12301 ccaggccata aaggcgtttt caactttggt tgcagaggat gaaacagtat caggcattgc
    12361 tgcatattca tcacgcaacg ccccaagctg actaatcagt gcaggaacaa ccttatcggc
    12421 ggtcagtttt ccgttatccg ccatggcctt cagatcctta cgggcaaccc ccattcccgc
    12481 agccagcgca cgaataacac gatcgccgtt ctcattcacc gagttaaact cttcaccgcg
    12541 cagcactccc tgcgccagtg cctgactgaa ctgcatgatc accgaactgg cttctgctgt
    12601 actggcaccg gataatttca ggcccgtgga gatcgcctcg gtgactttca gtacctcctc
    12661 agaactgtaa ccatactccc gcatggaagc tgcagaacgg gcaaaaaggc tggcgttatc
    12721 agaaaacgcc gtccccgttc tctggctgat cgccattaat tcacgctgtg atgcctgaaa
    12781 atcatcactg gactgtgagg cctgcttcag acgggcattt actgaattcc actcatcggc
    12841 gagagaaata agatgaccgg tagcaaaagc cccggcaaat gcccccgcca tattcagtgc
    12901 cgaagattta gctgtattta tctgatccgt cacttctgcc agtgcacgcc gcatttcacg
    12961 ggaggcagca gcagactgtt ggcctccgtt ctgcatggtg cggtagtaat cctgccccat
    13021 acgcgaagcc cgggagatct ctgactggaa tgaccgggag tttgccgaga ttttaataat
    13081 cagttcacgt aatgtcgcca cactcattct ccggacgaaa aaaaaccgcc gaagcggtta
    13141 tgttgactca ctgagacact attaaaagcg cgttttccag tccggcaaat ggatctgaag
    13201 cgccttctgt ctgctccttc tcccactgaa gaagcgcatc attcagtgac actttgaccc
    13261 cctgcgcacc gtaaatagct gaaacaatct gggcagcccg gaaatcagcc cgttcgtccc
    13321 ccagcgggct gaacctgtca aattctgccc acatcatgat ttctgatgcg gacatttccc
    13381 ggcgtaactc tgacaatgtg cgccccatcc tgagcgccag catcatcaga aaacgcatcc
    13441 ccggaagcgc tacttttttt taacctcgcc ggcatcactg atcagttcca gagactgccg
    13501 aagaagccgc gcatgcaccg ggccatacac ggcaatcacc tgttcacgat catcctctga
    13561 aaatacgggt tgcagtccgg tatcacacag aacatcaatg aacagttcaa catctgcctc
    13621 cagatttcgg cgggcgcgct ccgcaacgga taacggtgtc tcatcatctt ttgctttaac
    13681 gatctcctgc cagcgcaacc aggcttctgc agaaggttcc cgtaacacaa ccgttgctcc
    13741 ctcccattca ggcacatcaa cggttttatg gcgaaacccc gacatcgttg ccagtgccag
    13801 attacggata tttttagtca tcacatccat cctcattaac tgacggttac agtgcaggaa
    13861 gtggaggtca ctttgttaac cgggctcgct gaatcagaaa tctcgcaggt atacgcaccg
    13921 gcatcaccgg atgctgctga tgccttactg aacgttgccg ccgtctgtcc ggaaacagga
    13981 gaaccacctt ttttccaggc ataagaataa ggcggcacac cacccacagc ctcaaccgcc
    14041 atttcaagtt tcgctccgga agcaacccgc agcgtgcttt ttaaatcgac cttcactttc
    14101 agctgctctg tcgtcagcac aggcttacct ttcaggcgca gagaaaacgt tgcagccaca
    14161 acaccattgg ttcctgcaga ccaggtatgc tgacgcacct ctgccataaa ggtaaatccg
    14221 ttgcctgacg gaaaaataac tttaaagcca tacgtggtgt cattgtcata ggcactgcgc
    14281 aacgcgttct gggcagcatt cagataaaag ttgcctgaca tggaaatctc tgaagcagcc
    14341 ccaagaccgt taatattttc ctgctcaaca gaatacagcg tggtgacatc aatatcctgc
    14401 ttttgtcctg cggtaaactg cacctctttg attgtacagc tcaggccaag atagctggca
    14461 gaatccaggg tttctgctgt taccggtgca gacgaaatca taattttcgt cagttgcgaa
    14521 cgctcaaaat tagaggacat actcgtctcc tgaaaataaa aaaacccgcc agcggcgggt
    14581 gggtaaaatc attaatgacc tcaggctatt acctggaatt caagcgtggc tctgctcaga
    14641 cgggagtcag gatcataacc ctgcgtttta gaaataacgg agggtgccag ttttcttacc
    14701 gcatcaagcg cctgctcacg aatattatct gcgtcatcag gtactgtcgc ccagacatcg
    14761 atctgcacgg taattctgga ttcagcctgc ccatcaagca catcagatac cgtgtcagac
    14821 accacagaaa acaccagcca cggcggagat actgcaggct ttccctccgt cagcgggacc
    14881 acataaggat aaacctgtcc tccggccagc tgagacaaca gggaatacag tgtgccctcc
    14941 ctcatttact taagacctca tcaatagcct gattcattcg ctgtatggca acctgcgccg
    15001 ccagctcctc tgtcgtatcg aaagccgggc gaatgaatgg atgcgcgggc atgtttatcg
    15061 ttcccagctc cacaaagcgc cagtaaaatg catttcgggg atcgctggct ttcatgctgt
    15121 tatcactgtt tccggttcgc aggttccgtc cgcgaatgtg gacacccgag ataatttccc
    15181 cccgacgctt tgaacgctga gtgagaacaa ccacattttt cttcagtttc ccggttcgct
    15241 ccggcgcacg ttcaacaact gcatcccgca taacttcagc accggcacgg gtggcatcgc
    15301 gcagaacctt attgttttct gccctgctga gcgtctccaa atcccgtgca atatccgcca
    15361 ggccggaaaa atcaagactg aaatccatca cacattcccc ttcaggctgc agagtatttc
    15421 aagccgggta gcgcgtgcat ccggtattgg tggaccttct atacccagaa tggccccttt
    15481 aaatgcaccg gtcagcactt tcagacgtga agtcgctgtc acatcgcgcc ggaatctcat
    15541 ccagactctg accgtagcct gagcggtttc tgctccgcct gagattatct ccctcccgct
    15601 gataccctta acttctgccc atacggtagc tccctccgtc accgtctcca ccggatgccc
    15661 tgacggagag cgggcggtgg tgacattcag aataattacg cgatcacgta atctgcccgc
    15721 ctgcatgtct cctcctacaa aggaataaaa cgataaggct ccagcagaga agaaaaacca
    15781 aacgggactg gtgccttact gacatctgag gaattttccc ggttttcgca ccagtgcccg
    15841 accagcaaca tgagcgccag caaaacatca tcagctataa gcaccccttc aggatcacct
    15901 tccggcaccg tctcctcata aagcttacgg ttgataaaat tttctgcctt gcggcaggca
    15961 gcccggaaat acagcatcag taactcatca tcagttgcat catctgtatc aatacggcac
    16021 tgcgccctga gtttttccac tattgctgcc atcagaaact cctgcccgca acactgtgcg
    16081 ggcataaaaa aaccgcgtcg gcgcggtctg taactgaaca acgagtggtt atttgccagt
    16141 gagcgccttg atggctgcca catcttccag cacacagtca aaacgatgga aagccagaaa
    16201 tgccacctga tcaaactcag cataacgctc aaccagacgt ttcagttcca tataagtaac
    16261 gcggcgaatg ataaagcggt tgaaatcccc caggaaaatg aatttttttc cagtaccaat
    16321 cccgtcaata gcctgatcaa taacataagg gatccccagc acagtagccg gcgtaccgcc
    16381 tgcaatatcc ggcagccata acgggcgttt ctgtccatcc tccatctctt caatagtctg
    16441 caatgtggca tcattgaatg cccagcggta tttcggccca ccacgatatg ccggatcaat
    16501 ggcatgtttc agggcattca tttctttcca ggtgaaagcg gcagaggctg cagtctggat
    16561 ggttcccgtc accgacgctg ccagcccttt tggctgtaac ggtgatcccg ttccggtccc
    16621 ctgaaccaga tattttgcct ctccacgacc aatacgctgg gcaatacggt ttgccagata
    16681 agattcaata tccaccccac tgtcctggag cagctcattg gacacacgaa ttatttttga
    16741 tgacagcttt ttagccccca gaatagcggt cccgaacgtc acatcctgtt ccgttgcggc
    16801 tgtattttcc gccagcagtt cgccctcttc agtcgtgcca tcagacgttg accaggtgat
    16861 atcctgcccg gttgatgtgg tcagaagttg cgccacactg gcaatcccgc cataagcctt
    16921 catggtgtca atgattttgt tacgcatctg cgtgggcacc gtatatccgc cctgagaatc
    16981 cgttgttaca ctctgagccc gcagttcacg catcagatta cgctcttcag cattcagttc
    17041 tgcaaatccg gcacgcagaa aacggttaaa tgccgcagca cgcttctctt ccaccgcctt
    17101 tttcccgttc tccgcctcat tattctggcg ctcttccggc ccggactcat ccacatatgc
    17161 ctgatcctga cggcgcaact cttcttcacg ggcgatttgc tcatccagcg catccagctc
    17221 agctttcgcc ctgttccact ctgcccgttg ctcatcagtc catgcgttat caccaatttt
    17281 ttcatgcagt gcacgcatat cctttgcaat ggtgtttcgt ttttgcttca tctcatgaag
    17341 tttcatcgtc agtagtatcc ttatgcatta agaagggtca aaaggcgctc acgcgccatt
    17401 cgttcattaa cagctttctt cagcgcacca ctcgcccgcg cttcctgcca ggctttcatt
    17461 gagcggacac cggagtctgc gtcctgatag gccggatatg tcaccgggct gacgtcatac
    17521 agacgagaaa tgcgcgtgat ttcccggata acaatcccct cgtcgtcttc ataccagctc
    17581 tctccgtcac gggcgacacg aaacgcgaac gaggactggt taatgtcacc acgcaacatt
    17641 ggagacagca ccaggtcaca aatagtcgga gtatccggtg caacaatgtc ataacgtaaa
    17701 ccgcgttcat ccaccgacaa tgacaatgtg ccggcagaac ttcgtccgag aatgaaatta
    17761 ggatcatgat taaacaagcc acgtacatca tcattcagta catcatcaaa agcccccggc
    17821 ttgatgattt cacgaaatcc ccacagaggt tctgaacgac tgttaaatac cgagccatac
    17881 cccagaatgt gggtcggggc attatcatat tgttccgccc gcacctcccc gctgtaacag
    17941 cgcgtttcac ggtcattcat cgttcttttc ctctttgcct ttcgtatctt taaagttatt
    18001 caacggattt gctgcattta cgctgaccag catttcatcc agaccgtcaa ccgggttcat
    18061 atcctcaaat gccctggctt cattccgact catccagcca tctgtaatgg caaagtgata
    18121 gaactgcgca cgctcctgtg gggtcccacg gagcaacccc gtgaggttaa aacgaacgta
    18181 atacccggca gcccgttctg tacgggtaaa caggcgacgg ttaagctcct gctcccagtt
    18241 cgcaacccag ggcatcatcg tgtagcgaac aaactgaatc gcctgctgcg taatattcga
    18301 aaatgtggct ttttccaggt cattaatcat gtgcgccggg acattaaaaa tccctgcaat
    18361 catcgacctg ttcagcttgg tcatatcaat gatctgagca tccaccggag aaactgtcag
    18421 agcgcggtaa tccagttgcg caggcaacag catggtttta ttttcctggc tgcgaagcgc
    18481 tgtcaccgcc cgctgccaca tatttttaag cctgccccag ctctgttcgt tcagttcatt
    18541 tttcacagaa ataataccgg caggacgggc attaccgtta aaaaaggcgc tggtatactg
    18601 ctggccactc attcccatac caatggtttc agcatgctgc atgatcgggc tcagtcccat
    18661 tttctgattg tttcccagcg ccctgatatg gatcatgtcg tccggactta ccgcaaatgc
    18721 accctcttcg ttatacaccc cgtaagtatg acgcccaccg gtgttaagta acgtggtttc
    18781 ccatggcata cagcattcaa ggctggtaac ctctccacga cgattacgtt ttacccacgt
    18841 ataaccattg ccccacccca gcacatgacg ctgcttcagt tcccgccact tatagctggt
    18901 ctgccaggca ttaggttcat catgaacgag ccagaacaac ggatgatcgc gtgcaggctg
    18961 aacatgctca ttcgtttttc gcatcacatg caggggcatc tgagccacac tggatgaaat
    19021 aacataaata caggcataga cagcagccag cttcatggat gtttccggac tgacatacac
    19081 atcccgggca aaaatattat ccgtctcagc ggcctctccg gttaccggaa ccgagggatt
    19141 ttccagagac tcactgcgaa acagagcatc aagaagcatg ttttctcctc atggacacta
    19201 ccagtgcata aagcagcaac aaacagcccg acagcatcag agacgctggc agacctgcat
    19261 acagataaac gccagcagtg agcaaaccga aaccgatcag cccggtcata tcagtaataa
    19321 gctgtttcac agaattaaca ggtcctcatc aggatcaagc gtggacagaa agtcattcac
    19381 gcccccgcca tttaccagaa agcggctcat ggccgtaaaa agcgcaacag ggccgtcgat
    19441 tttggcttca ggcgtggatt tattcgggaa gatgttgtcg tttttgtccg gttttaccgt
    19501 aacgttagac atcatccagt tcatgaccgg atgattgctg tgatggaaac gcccggcata
    19561 aaccagtgat tccgtttcct tcatggcctc tgacagattg cggaccgtct gcggaacctc
    19621 caccagcggt atcccttctt cagccagtgc caggctgaac tgcattgcgc tccacgggtc
    19681 aaatcccagt tccctgaggt tttcaccgcc aatccattcc agtaagtcac tttttatctg
    19741 agcatgatcg ataacatcac catccgtcag gatgagctta tccatctccg cccacttccg
    19801 gtaaagttct gcctgctgcc gcgagcatcg ctccagccgt ccttccggaa gccagaattt
    19861 aaaatcagca tgaacatgtc cgttatcggt tcgccagagt tttgccgccg cacagatatc
    19921 aatcttatga gcaaggtcga cgccgaccca catgggatat gttttcagct catgttgtgg
    19981 agcaatgtat tcgcacttct cccacttaat catatccatc caggcagatt cggcagtgac
    20041 ccacacattc atgtgtttgg taaaaaaatt cacccgcgca gagacctgct ccttcgcttt
    20101 tttcgccaga cgacgcagat catcccagcg tttacagatg cccaggccag gattcgcttt
    20161 ctgccagacc gtttcatcaa acggatcatc tccctcatcg agcgtgtaaa tgatcgcaaa
    20221 gtaggagtcg tcttttaccg cgccctccac gtcgctgtta tagcctcgca ataccttaat
    20281 ggcgtaatcg cgctgctcgt agcaaatccc ttccttgtta aagccagccg tggtgatgcc
    20341 aaataacaga gactgcagac gggcaccggt tgccgtttcc agaacgtccc acacgtcacg
    20401 ggttttatga gcatgcagct catcaataat ggcgcagtgg atgttcagac cgtccaggtt
    20461 gtttgcatcc gaggaaagcg gttcaaattt tgatgcgctc tgctcctggt aaatcgccag
    20521 cttgttgaaa tcaaacaacc gcccgagtgt cgaccgggct tttctgacca tatttttggc
    20581 gtcttcaaac acaattctgg cctggtcacg cgtggttgcg gctgaataca cctcagcccc
    20641 gccttcacca tctgcccccg tcatatacag accgataccc gatgacaggg ttgattttgc
    20701 gtttttacgg gcaacttcgt tgtatgctgt ccggaaccgg cgcaccatca ccgggcgtcc
    20761 actgccatcg ctgcgcatga caacttcccc ggtttcttca ttcaccagcg gaatgacaaa
    20821 accaaaaata ttaatgagga taaacacatg ccagtccatc aactcaatgg gctgacctgc
    20881 cagcgcccct ttcacatggg gtacaaattt gtagaaatta aggatgtgct gtgcacgggg
    20941 ttcactgaaa taaatccccc gctcttcgcc gtacttcaga tcatcaagaa aacgctggca
    21001 ggccagacgg acaaattcgc cagcaacaat ttctcctgca acaacacgtt cggcgtagcg
    21061 gatcccgtca gccacttttg ccatcagtct ctcgctttta aaagctctgc cagcggatca
    21121 acatcatccg gtccggcggt atttactttc gcccggcttg ccggtgacat accaaactct
    21181 gcaagcatcg cccgaatccg cttccaggca tcagccttca tcgcagcagc cgggtgtgcc
    21241 ttgatcagca catcgccatt ctgcgtttcc gtgcggtagg tataaccctc aacatcgagt
    21301 atttcgcagt gatgccggta ttcggtgtag gcttccacca gtaactcgag cgcacgtgca
    21361 tcgagctgag aaatgatccc ttccgcattc agctcttccg ccattcgcct gaaccagtac
    21421 ttcccctgcg cccctaaatg ttgcggaatt ttagggagac ctttttcatc ctttttagcg
    21481 gtttttttgg agtctttaac tggccgcttt gaggggttac ctcgtatcaa atgcaggcgt
    21541 ggcggggttt tcgggggtcc agacataatc gattttacct atcaatcatt taatcacatt
    21601 ccaaaaaaaa gttttcgaac ctgcggcgat gcgaggaaag gtcaggcggc ggtactgagc
    21661 agccagggtt gcagagattt gacctgcccc tcccctacag atgggaactg ttatcaattg
    21721 aggcgttcgc gcgctgtttt tgctttatga cagggccagc acagactctg caggttactg
    21781 tctgcatccg tgccaccatg agctttcgga atgatgtggt ccacagttct ggcttcaacg
    21841 gctctcccat tgcgcaggca gttctgacac agatgattat cacgcttcag tatgcgcgca
    21901 cgtatggcat cccatttcga gccatagcca cgctggtggc ggctcagtcc gcgttgatgc
    21961 tgtacccatc cttcgccacg atgtttatcg cagtaaccag aactgtctgt ggttgtacct
    22021 gcacatccac gcttacggca ggcgcgtggg attcgtgggg gcatatgtac tccaatgaag
    22081 aagccaccga catagcctcc tccattcata gtgaaactat tttcatctac ccagtaatga
    22141 attctttgta gagttgtgat caatacaact cactaatgga gaggcttgtc caacacgttg
    22201 gacaagtttc ctgtttgatt tactggacac tatagaagga cagaatgcct tcatcactcg
    22261 aataacatca attaaggagg ttcaacatgt ttcattccac aaatcatcag gctgtaatta
    22321 tggctgcatc agcttgtgcc acagaccttt tccgcttcac tttgagcctg attcatttct
    22381 acctgaccgg ctcgcctcta tctttttaat ccccgcttta tccaaattgc attgccagaa
    22441 tgccgacaac agactgacat tcaaatcctg actacctcca ataggctgag catccaccta
    22501 tatagtttta attttcatca atccatttaa ctatcgttta attgttgtca cataggattc
    22561 tgccgttttt aacaatgcag gataataaga tgaaaaaaat gttgttttct gccgctctgg
    22621 caatgcttat tacaggatgt gctcaacaga cgtttactgt tggaaacaaa ccgacagcag
    22681 taacaccaaa ggaaaccatc acccatcatt tcttcgtttc gggaattgga caggagaaaa
    22741 ctgttgatgc agccaaaatt tgtggcggcg cagaaaatgt tgttaaaaca gaaacccagc
    22801 aaacattcgt aaatggattt ctcggtttta ttactttagg catttatact ccactggaag
    22861 cgcgtgtgta ttgctcacaa taattgcatg agttgcccat cgatatgggc agctctatct
    22921 gcactgctca ttaatatact tctgggttcc ttccagttgt ttttgcattg tgatcagcct
    22981 ctctctgagg gtgaaataat cccgttcagc ggtgtctgcc agtcgggggc tggttgcatt
    23041 atccacgccg gaggcggtgg tggcttcacg cactgactga cagactgctt tgatgtgcaa
    23101 ccgacgacga ccagcggcaa catcagcgcg cagagtttca ttttcagctt tcgcattggc
    23161 taattctctc gagtactttg catcgagtgc agcaacatca cgctgacgct gctgcatgtc
    23221 agcgatagtg gcgatcgcct gcttcagctc actgactttt ttatcacgct gttctttgta
    23281 ggcgatggcg ttatcacggt aatgattgac cgcccacgac aggcagacga tgatgcagat
    23341 aaccaaagca taaataatcg cggcgactct gctcactgct ctatccccca acaggctaat
    23401 gcgctttcct ggtcacgacg aataacctgt ccatagcagt tatttgaacg tatgcggcaa
    23461 tcgcgcccac catcttttat ccaccagcga atcgcctcgc atgcgccctt acgatcaccg
    23521 gcattcagcc gcttataaaa cgtcgacggg aaacacttac cggggccaat gttataggga
    23581 cagaatgacg ctatacccgc tttttgtggt tcggtcagta gtactttaat attgcgctcc
    23641 acccatgcca gcgccttatc acgctcaatg gcgttgacct ggtcgcattt ttccttcgac
    23701 agtttcatac cgggaaaaac gggttttcca tccaccatcg tggcaccccg acagatggtc
    23761 cagatgccgg acccatcgcg gtatgccgtt gtgtggttac cttctttttc atccagaaac
    23821 tggtcgagaa tatcaggcgc gggcgcaccg acggcaatca gtgccagaac ggcagccgac
    23881 aggccgtatc tgatttttgc gttcatggat atttatcagg atttatcggt ttctgcccac
    23941 ggacaggttt atctgttccg gtcagtgact taaggttgtg attccggagg agtcttcaga
    24001 gaaccagtaa ttcttcccgg tagctttcct ttgtaggtta tccatacatt ctgcgcctct
    24061 aaaattacgg ggcgcttttc cggcgactgc tcatcccctt cacataaccc ggcagcaaca
    24121 tccaggaaga cctgtctgat actcattctg gctgctgcct cataaaactc cagcgcggca
    24181 ccttcaacac ggtccagcga gatgtccagg tcaaaaattt caccgtcaaa gcgttttttg
    24241 tcccgtaacg ctaaagttac cgtaacttta ttctcaaaat tgcggatccc tttcacaatc
    24301 agttcatagt tttgagtcat tgaattactc tccccgtgcc gccttacgac ggtcctctct
    24361 gattttgaaa tacaggttag tcagatatgt cagcagccca aacagcagac tccccagcac
    24421 gcctattgcc gcccactgag acggggaaac cctgtccagc aactgcagga accagtagcc
    24481 cgttcccacc gctgacgtgg tgtatgacac acctgttgtg attttttcca tctggtccat
    24541 accccgtctc ccgttatccg gaagctgaca acaataaaaa agccaccagt taactactga
    24601 tggctctgat aactcatgca agcgtctcag acgatccact gacactaccg gtgagtttaa
    24661 cgataccttc catttgactg gctcactttt tatgatgatg ccggtgtatt tatctccagc
    24721 accagacttt ctatctcaac gccatacgtt gcatttttgg taatatccgt cagcgtcagt
    24781 gcatttagtc ccactgccag accgtctttt atggtctgga atgccgggcc agtacgatga
    24841 cgtagtatca ctccggctca gttgcaccac tgaccaccac atcaccttct gctgcaatcg
    24901 cctgcatcag ggtataaggg gttatggcca ccggactacc aaacggctgc cagccctctt
    24961 tcagtttatg tgtcagcttt tccgcaagat ctgacggcgg cgccgccctg acaacatcat
    25021 agtgtttaaa tgccatggtt ctttccacca tctgaaaaat aattctttaa aataccagac
    25081 atgtaacaca gaaaaaacac aaaaccatac cttaaataga aacctgatca tcaagcagat
    25141 atgcatggat aaactacaag acgagatata aaccaccctg catttaaata aacaataaac
    25201 aacatcagaa aaataattct gctctatggt ttatattcaa aaatatcatt tatacttttc
    25261 agaacatcac cagcaaggca taaacaagga agctaaatga agtggattgt aattgataca
    25321 gttatccagc catcatgcgg aatatctttt tcagtcatat ggagtaaagt aaaattaata
    25381 atctggtatc aatcggatgc tttcttacct cctgaaagta tatttacact gactcacaca
    25441 ggtatcatgc tcaataacaa agtgctacct gtaaccattt acaacgtagt accattcaat
    25501 aaaacattct ggaatttaat caaaaacagc caggaatgcc ctacaaatac agataacgta
    25561 ttgaatgaat gctttaataa ccgttgcatt ctgcaaatat gtccttatgg actaaaacaa
    25621 caaagtccat aaggagttta ctcacatctg acaaaatcaa tataaacagc ccctccggag
    25681 aggggctgga gagtggcgct atgtgccatt gcatggtgcc gggtgcctcc cggtgaattc
    25741 agtaccagca cctgaatccg cgattatccc atatacctac tcgctgatta cccctccgca
    25801 cagggggatt caccatgcga aattttttaa caaacttccc gccggccaga caataatcgc
    25861 cagcctgaat tatgagcaac gtggcatttt acgggaaaac tgttttctgc agtaaaaagg
    25921 cccgccggag cgagcctgga aggatagcgg tcatgtgatg ccggtttccc ggtaactcag
    25981 catcggtatc tgagtcaacg ttttctctac tgggtcattt ccgatacgtt ccgccttccg
    26041 gcagactttc atcacgtcag aaaatatagc accctgagta acaggacagt actcagaatt
    26101 caggaaactg tgacacatcc tgcacagaaa agcccctccg gagaggggct gaagtatagc
    26161 ctaatttctg tctgtcgcat ggtgccaggg gcctcccggt aaattcagcc tgtctactga
    26221 atttgcatgt tctctggatc atacactttg ccagatgccc cgccgctgag ggggattcac
    26281 catgcgatgt aatttttaac aaattctccg gcagccagac aatcatcaag ctgtggaatt
    26341 gtgaggtatt taaaaatttc aacgggtaac tgataccctg ctaatcgcct gatgctttct
    26401 ttttcagcaa cgggaaagca acaaccacac acccgccacc aaaacaccat cagacagcac
    26461 cgacattatc cggctgctga agtccaccat caccaccaga aacaacagga gtgcaaccac
    26521 agctgcttag aaggcaattg ctctgcccgg ctgagctaac aacgctgaat accgataatg
    26581 gaccgccatc ggggacccgc ccccgcacca acaaccctgt tatcgtgtcg tctgctcttc
    26641 ctgataagct aatggcggtt tgtgatggtg gcccttgctg gatttgaacc agcgacctgg
    26701 cgattatgag tcgctcgctc tcaccactga gctaaagggc cgggagtaga ataataacgg
    26761 tccgtaacta attccgcaat aaaaaacccg ctcggcggcg ggttgtagaa actcttctaa
    26821 cgtcaggcat aaaaagccca ttattatgac gaatttacca cagattccgg aaaaatcaac
    26881 cttgttacct agttaccttt tttaactgcc gctcagccca tgcttcttca atatcaaacc
    26941 gggtcaccag cgcatcatag aatttcttaa ctgttttttc ccatgacgcg cgtgttatct
    27001 ggtttgtcac ctcgcatata gcattaaatg tctccgttga tggtagtctt tcatagccac
    27061 gaccaccaca acgctggcag tctctgataa caggcatacc acgttttacc gactcttcac
    27121 gatgaatggc gacaccacgc ccacggcaat ccttacaggc ggtggaaacc tcaccctttc
    27181 cgccacactc cggacaggca acttttacca cctccctgac ttttttccat tcttcccagt
    27241 aagacgaata cacacctttc gtacactttg cccataccgg cggcttacca tccggatact
    27301 ggaccttgtt tgtaaaaact acgctttcaa taaatttttc cccatagcaa caagggcact
    27361 gctttttact cgctgcgctg cgggcataat cctcaaaagc gtacgaagcc ataatgcgca
    27421 tcactaacgg ttttatttct gccggaagtt ttctcaacgc cgcaacacga tcgcaccgac
    27481 tgagtgcata atctgccagt aattctgttg cccgcgccct gtcattcata ctgatgccca
    27541 ttttccccag gaacgcagaa aaccccatct cagcccgatt ctgtgtcatg ccctgcgcgg
    27601 ccatcacatc agtgatactc agcgcatctt ttgacgttga ggccgatgca tcggtcaggc
    27661 caggggattt tggggagtag tatttcggta aatcttccag tttcattttt tgacctgctc
    27721 ttcatgcatt atggggtaaa tcttcacccc cagacgtcca ccagatactg gctgaccacg
    27781 aacgatattg atttcatcaa actgctcatc gtccattaac actcccgcat gcgtcagcgc
    27841 atccagcggt gctttcagga tattgtccag gtcgcgacga cgcttatccg gtggctctgc
    27901 aatcaccttt atcgccagcc ttccggacag gtttaatttc agccgctgct ggcgaacaat
    27961 tagcgccaca tcacggcgat aacgctttcc ggcctccgag atgaaatacg tattgccatg
    28021 acgtcgccag taggtattca ccgtcggcgg gtaaggcaaa acaaattcta tgcgttcagt
    28081 cattcatgct ttccacttca ggacacccga atttctcgcg tgcattaaaa aacgaatcag
    28141 caacaacagc tggctgccgt gtttttcttc aaaatctttt accccggcgt gcagttcgtt
    28201 atgacattta cggcacagcg gaataacaaa caaatcatca gcctttgttc ccatacctcc
    28261 caggccatga ccaatgatgt gatgcggatc atctgcctga ttaccgcacg tcatgcattt
    28321 ctgcgttttt acccagcgcg tgtatacagg catctcttcc cgttgtggtt tctggcgctg
    28381 gagatactga accggagact ccggatcaac ggcgatgctt actaacgtct tttcctggag
    28441 tgggggctgt tgctggtgga cgtgaagtgg cagcgcaata ttttttgtgc gctgcttcag
    28501 tatgctggtg gcagtctgtt ctcccggtac gatgtcactc tcacggtata cggagcggat
    28561 tttttccacc ggtaatccca gtgaacgaca caatacagac tccggaagcg catcagccac
    28621 ctgattgcag accgcccacc aggataattc ggccagcgat aactccctct cctgcgtacc
    28681 gctgattgcg tgacggatga cgtcaatcat ccatgctgac aagttttgat gagcaagttg
    28741 cccgagtgat tctgatgtct ggtcccgcaa ctggttgtca cagtgccagc acaacaccat
    28801 cgcgccggta ccgtaacggt gaatgacggt ttcactgtga tgatagtcac catgaggcca
    28861 ctggcaggat ttgacatgac gcaacagcca gtcagacagt gccccagcgc cgccagcagc
    28921 acgaatcacc cgatcatcgc tgaaaaatgg cagtaatgat ttatcctccg ccagcggctg
    28981 gcgaacggca gggacgactc cggacggcag accgcgcatg cttttcggtt caggctccac
    29041 cagcactcga gggttatgaa atacttgcat ggattcacgg cccggcctaa ggaccaccag
    29101 cccgagttcc ggtaccagaa caggtcgaag taatatccgc acgttacctc cagatccgtt
    29161 gctggtatgt gcgggatgaa cgcggtgggc gttcggagta agggagtctg actgagatta
    29221 tccagtgacg gtagtcgagg ctaagagctt tcttaacctc gtatccgcgc ctgcggtaac
    29281 actgaattat ccattccgcc tgctcttcag tgcatggagg atgctggaac cagtctgatt
    29341 tgaatgcgtg aaaacgccgt ccgcacctac tggcaaagac ggcagaatca ttagaattgt
    29401 gtaatttggt atcgtgcgcc atcggttgtc tctgctggcg cagcaggtgc cagttgttca
    29461 ggctggcgtg cgaattgtaa accagaatgc caggaaaaaa caaaacccgc cgaagcgggt
    29521 tacgtgcggg tgcgttgagg atgcctgaca catcagaggt ggcgagggat ttctcccccg
    29581 ccaggtctct tactcctcag gttcgtaagc tgtgaagaca gcgacctccg tctggccggt
    29641 tcggattcgt acctcgcaga ggtctttcct cgttaccagt gccgtcacaa tgacggttaa
    29701 acagatgacg atcagggcga ttaacatcgc cttttgctgc ttcatagcct gcttctcctt
    29761 gcctttcggc acgtaagagg ctaacctaga tttgccgttc atagattgag cctcagatta
    29821 atgttaagcg tcttgcagga cgcgtaatgt taactggggc ttttctctat ctgccttttg
    29881 gtgttcatgc ctgagacaga tagcctcaag cacccgcagt cattctactt aactaagatt
    29941 tccccgcaaa ccgtttttgt ccggcacagt aaatatccaa ctaaaccaat ggcgttcgct
    30001 gtatttaccg ccagtattca atgcacatga ccgccatgaa cacccctaaa aaaagggcat
    30061 ttatatatcc aaatattaat atcaaaacat caactttttc catatacctt gctgtgaaga
    30121 tgatgggcat acatgatacg aacaaccaga acgcaacaaa caaaaactgc aatgcgtttt
    30181 tcattattcc tcctacaatc aatgtgcaat tacatttaaa cacacctcaa tttggccgaa
    30241 catataaata tctaaaccag aaaaaatcac ttacatagcg ttacaaactc tttagtctaa
    30301 atattcatcg taaaacattc cccatactta tcagcccgtt ctgcgccagg tagctcattg
    30361 ccttatctgg gaatctgtaa tcaggtttcc ggatgctggt ggattttcgc gttttagttg
    30421 ttcataaaag tgcacagctt taaccagttc ttctgatgta accgggactg gcggggcagt
    30481 gaataaggcc tgaatttcat agttcggcct gtcgttacaa tcctcttttt tcggtacata
    30541 tttccagtca ccagaccact acttctcctg aaagtccgta acgccttttt tttcacgtag
    30601 cgatatcgcc atgccactgt ttttgcttgc cccgccgttt catgcccttc ctgataatta
    30661 acctcgctca ttcatcgccc cactcatcac aatatgcttc gaccggagtt tttcctgctt
    30721 cataatcatc acgccatgct tcagcatcag cagcactgcc accacgtaac tctgcatagt
    30781 ccattaacag ttcatgccat tcttcaaaac tgacgttgta tttagttgaa ccaaaatcag
    30841 ccattttgtt cttcctcttc gtcttttatt tcgtgatatg agtaattgca gtagttaaag
    30901 aaaatatctt ttgcttcgtc atgtatttca tcaggcgtcg catcatcatc cacttcgaat
    30961 tcatcctcga aatctccacc ggctattccc gtttcaataa ttattttaaa ctttcgcatt
    31021 taactaccgc cctttcgggc ggcctcctga tgttctgagg gtgcagaaat ccctccggtt
    31081 aaggattaaa tttttaacag agctaaattt aattattcag ttctggattt tgtcgccctg
    31141 cgtatccgcg ctttcgcgtt acgctcaatc tgaattagct tttctatatt ttttcgcctt
    31201 tcccgctcct cctgacgcaa gagccttaca tcatctgcca gtctggtttc tcttttcgcc
    31261 acagagagca tccagtcaaa tggctccaca actgcaccgc agattttaca gcggacctga
    31321 cgctcttttt cgtcaacccg gacagaggcg tgatgacaat atggtctttc cgatggctca
    31381 taaagaaaat taacctgatt acgagggtca tcctctttta ccggaaataa aacgatattg
    31441 cttaactcat cctctggttt tatttccatg ctcctctcct ttgatgcgaa tgccagcggt
    31501 aattgaagcc tgatagctaa tttcactcac agtaccgcct cctgaaaatt accctgatag
    31561 aaagccagta cacgctgcat agcttcactc ttccggcact cgcgacagat tatgtttagg
    31621 cgactgtcgt agcgacgtat ttctccgtca ggtaacgacc agataaggtc cggatcaacc
    31681 acaaccggtt tcttcagctt tgccctcgat aattttttgc gggcattttg ccagtcttta
    31741 cgagcctgtt cagacgggaa taacccgtag ccagaattgt atacatcgcc actggcaacc
    31801 agctctctgg ccagaacgct catcagatat cttgttgccc cagttttagc ttccagttgt
    31861 cgtaacgtct cgcgcccact ctggcgtacg agttcaagaa cctgtccttt aattttttcc
    31921 cgctcttctt gtgtaaaaac ttttgccaca agccctcctg aaaattacct catgaccaga
    31981 aattaacact taccccctga agcccggcgg aatttcgtta tccggttcag aaatatgatt
    32041 cacacaacgc tggttgttcg tgccgcttac cgggagcagc caggggtttt caaaattccg
    32101 gtccggtcca aaaaacgtcg tcgctcgctg aacaaattcc gttcccgttt tcccggtagc
    32161 cgcaaggtat cttgcgtaac gcctcacgcc atccagcatg gcctctggtg gcaccccctc
    32221 gcgtaatctg gctttccagg cactgaaagc ggatttcttc gggtttgccc cggcacgcaa
    32281 cgggtattcc cgccagacct gttcgaacac atcaggataa tccactcgtc ccacaggctg
    32341 cccggtgttt tccgggacta cccgatcggc ttcccgctga atggcggaat cggcttcagg
    32401 ctgctgaagt tggtgtgatt gctcctgcct tgcggtcatc acctgctgca cagcgcccga
    32461 atcggctttc agcgcatacg ctgaatcggc ttccggtgtc gtgcctgcgg gctggccagg
    32521 agtgacggtc tgaacatccc ctgcctggtt cgtggcgttt tttacgccat ggaccatagt
    32581 gttttgatct tcttgatctg tatctttatc tgtatcttta tctgtcgtga ctcgtcgtga
    32641 catgtgcgtg acatttcgtg actcgccgtg acaatcgcca ttttgttccc gctttctttc
    32701 cctctctcgc tgcgccctct tgcgctctgc cggagatttt gcggtttgcg aaatattgcc
    32761 gttgtcctct ttcagcacct ggcgtttttc ccatccagtg attaaatcac catcaagtac
    32821 ccgcccctgc atcgtctgca aaattgaatc aattacctct tctgtcacgt cgagcgcact
    32881 tgccaaatct tctgtcgtga catcaatgtg acctcgcgtg acatttcgtg acgcgctcac
    32941 caggaggtgg atatacactg ccatcactgt tgcaattggc tgccctgaca ccctggcaat
    33001 tgttcgccac ttagggtcat ttggcatgtc atgccataat ctgagccagg cgttagccat
    33061 actcacctct tctgataccg aatcttttta ctcacgagtt gccggaagcg attcgatatg
    33121 actattgtca gtcaatgtac tgccacagca tttcctgccg ggccaccacg gttcatctga
    33181 ttgaaaccgg cgattgccac tgcgacaaaa tcatcagcgt ctctcaccag tcgctcccgc
    33241 gtctccacca actcccgaaa ataagctgaa ctgtggctgc gcattctggc caccagcaaa
    33301 ggtggcattg ccttttcgat cgctggtaac aacgcctgaa ttttttcaac tgcatcaggg
    33361 gtgtctttct ccacccagcg gaaaattttc tgggtattgc gagccagggc ttccggatgg
    33421 ctgtcgtcat acagttccgg gaacgtcatt cccagctcga aatacgcttt ggtaattttc
    33481 gcagccggta ctttttcgcc gtccggatgc gcccaggcat tcatcgccat gcggatgtgt
    33541 tcatgcttga ttttcatgaa tccccccttg gttagaaggc ggattatgat cagaaccggg
    33601 aatgacaacc gtcggtatgt gtaactcata tttgagcgcc ccggcagtga ctgcctgaat
    33661 tagcaacgcc catttccacg gaacctcttc cccccacatg ctgactgtgg tttttgacgt
    33721 tcctagagct gcggctgttt taacaactcc gccaaaatag cctaatactt ctgatttttt
    33781 catgagtcgc tccataaaac tgaacgtcaa aagtttaata atcaaaacca aagaaagtca
    33841 agaaacaaaa ccatctgtgt tttaaaatca aaacatgagc aagcaaacta tatctgaacg
    33901 cataacccaa cgtatgcatg cgctaaacct gaaaggcaaa gaccttgtca atggcactgg
    33961 cgcatcaaaa ggctccgtaa gtcaatggat gaacggtgga ggagcgccgt cctcgcgtta
    34021 cataagttca ctggcaaaaa tattgaaagt aaacgaaaat tggcttctta atggaggaga
    34081 gttaaataca ggtgattcgc ttgatctatc tttaccgccg ataaaaacgg ttccgctact
    34141 atcacttcag caggcagcaa gctggagtga ttatatgaaa aattcctcaa taacctcttg
    34201 tgtgcagctt gtcggagaaa tcccggtcaa tacctttgca gttgttctag agagtgacag
    34261 tatgtcaaca tctggtgggg gagtttccat cccaaatggt tcaacagttt ttgttgatcc
    34321 cgatcgaacc gtacaaccag gaaatattgt ccttgcctta cccaaaggga ccacaacacc
    34381 tgtcattcgt aaactggaga tagaagggcc ggatattctt ttagtcccca cgaatcctcg
    34441 ctacccttca attatgctgg atgatctatc ttgcatattg ggcgtatgct ttaaaattca
    34501 acaagatatt taaccaacct catctatttg attaactgta tgccatcgtg gtgatggctt
    34561 aacagctgcc tgcttaaaat gttttgataa aaaaacattg acctgaaaag ttcgtttttc
    34621 taaacttcat tcattccctc accccatcct acagaatgca gggcaatact tcgagttacc
    34681 aggcagtggt caggggttaa gtagccagcc cgaggcgtaa gaacatgacg gcagggttca
    34741 actttaataa ctatgcagca ggtttttgtt ccgctacccc ggcgttaagg ggaaacagag
    34801 gatttctcag tgggcgaagt caaacatcag aatggaaggc gtccagggat cagcaaagaa
    34861 acagcgatgg cgctttatat tgatatcagc gccattgccg gtcaggtaag aattatcaga
    34921 gcggtaacta agcggtatgc gcctttactt cagaaagtct ctggtgagtg caccgaagat
    34981 attgtcaacg atttcgtcat caaactgcga ggactcatct tcagttacaa ggtgaccaca
    35041 atttttgcag atggctcccg cgaaactgtc agagccctgc ggtttaaagg atgtgtcaaa
    35101 gacttcgcca ccacattctg ggcaagaaaa cttgattgta ttcataacca atttcctctc
    35161 gagtaacaga cccctcagag gataccacct cgcctgacgt ggttaaaagc aggcaacgct
    35221 aaccacaagg agccgacatg cagaaacgag aacccgtcat catcgcgcca gactataccg
    35281 atgatgaact ttatgagtgg atgcgccaga aaattaatgc agcgcaggat ttgaaatggg
    35341 ccaatgaagc cagggctaag caggctgaaa atctgtccgc tctggagcag gatatcacca
    35401 ggctggaaaa agcagcggca ttaagcattg ccagaatgat tacatacccg cgttaataga
    35461 taaccaacga agctaaggtt ggtaattaag gagttctcca cgggtgaggt ggagtgcgtg
    35521 cgccggacac gggtgagcat ccggcactga cagtttactg aaaggatatt tccctgaaaa
    35581 gtcagaccat aacgcgaaag cgcacggcga ggtagctggt tcatagatag cctgtcgtta
    35641 aattttcgtc gaccgtgcgc ttccggttgt ggcaatccgc gaaatggcgc ggcggtaagt
    35701 atggcggggt tattccttcc cccgttgagg acaccgggtt gtcaggttga ccatacgctt
    35761 aagtgacaac cccactgcaa cgccctctgt tatcaatttt ctggtgacgt ttggcggtat
    35821 cagttttact ccgtgactgc tctgccgccc tttttaaagt gaattttgtg atgcggtgaa
    35881 tgcggctaag cgcacgcgga acagttaaaa ccaaaaacag tgttatgggt ggattctctg
    35941 tatccggcgt taattgttaa ctggttaacg tcacctggag gcaccaggca ccgcatcaca
    36001 aaactcattg ttgagggcgc gataatgaaa acgttattac caaacgttaa tacgtctgaa
    36061 ggttgttttg aaattggtgt cactatcagt aatcctgtat ttactgaaga tgccattaac
    36121 aaaagaaaac acgaacggga gttattaaat aaagtatgca ttgtttcaat gctggcccgt
    36181 ttacgtctga tgccaaaagg atgtgcacaa tgaatccagt atttgcactt attctgacgg
    36241 tttttcttgt ttccggagag ccagttgata ttgcagtcag tgttcacaga acaatgcagg
    36301 aatgtatggc agcagcaacc gaacagaaaa ttccaggcaa ctgttatccg gtcgataaag
    36361 ttattcacca ggataataac gaaatcccgg caggatttta aaacagcacc gtaataaata
    36421 tccagtttca ttcttatatg tcagcaatgg cagagatttg ttcaccctta aatctgtgat
    36481 gaggtttacc aataatgagc actgataaag aagaatttgc actatattgc gaagcaaaaa
    36541 atgacaaagt aagaaaacgc ctaggaatta aaggtggttt ttactggact acagcaaaaa
    36601 aattatctgt tgcaatctcc cgctgcatta ccgcaatgga tgacaacgat tatgatgaag
    36661 acgactttaa aaaacccgtc cgcgtcaatt tgcccgttgt tgacgacctt ccgccagaag
    36721 gcgtgtttga tactgaattc tgcaaccgct atgaaaaagg cgggaaagat ggcatcacaa
    36781 tgacatttat cggcccttcc ccctctgttc aggacaaacc agccagcact gacaatacca
    36841 acatcaacgg cgaagccatg actgagattg aggagagcat gcttctgcct gtctccggtc
    36901 aggaactgcc cattcgttgg cttgctcaac acggcagcga aaaaccagta acgcacgttt
    36961 cacgcgacga actccaggca ttacacattg cacgggctga agaactaccg gctgttactg
    37021 ccctggctat ttcgcataaa accagtctgc tcgactcgct ggagattcgc gacctccaca
    37081 aactggttcg tgacactgac aaagttttcc ctaatcctgg taattcagac ctgggactaa
    37141 taactgcttt tttcgaagca tacctagacg ctgactacac tgatcggggt ctgctgacaa
    37201 aagagtggat gaaaggaaat cgtgtttcac gcatcacccg cacggcttcc ggtgctaatg
    37261 ctggcggtgg gaacaaaacc gatcgcaatc cgaatttagt acacaccctc gacacactgg
    37321 atgtggagat tgcagcagcc acacttccga tggattttaa tatttatgaa attccgggca
    37381 gcgtttatcg tcgcgcaaaa gaagtagtcc tgaacaaaga aagtccgttc aaagaatggt
    37441 ccgcagcact tcgtgcaacc ccgggtattc tggactattc ccgcgccgct atttttgcac
    37501 ttatccgaag cgcacaccct gaattttatc actacccggg acgccttcag gggtatatca
    37561 acgcctattt gacggaaact gatcacgaga accccagcaa ggaaactctc acagctgccc
    37621 ggcatacgcc ggaaaaagat atcctggaag aaattaaccg cgaggtggtt actgagcgtg
    37681 aaacagaaga agaaaaacca caaccatctg acgcaatggc aggtgaacag gcaacaactg
    37741 aaacaatgga accggataca actgaacatg gccagaacgc gcagtcgctg gatgctcagt
    37801 cgcaggtgag ttccgctaac caagtaaaag tcaccgctga cgaagtaaac aaaattatgc
    37861 aggcagccaa tatcagccag cctgacgccg ataagttact tgctgtatcg cgtggtgaat
    37921 ttgttgaggg gattagcgac cctaatgatc cgaaatgggt caaagggatc cagactcgcg
    37981 attctgtgaa ccagaaccag catgaatcgg aacggaacga ccaaaaagcg gaacaaaaca
    38041 gcccaaatgc gttacaaaac gagccagaaa cgaaacaatc cgaaccagtg gcgcaacagg
    38101 aagtggaaaa agtctgcacc gcctgcggtc agaccggcgg cggcaactgc cctgattgtg
    38161 gcgcggtgat gggcgacgca acataccagg aaacattcga tgaagagtat caggttgaag
    38221 ttcaggaaga tgatccggag gaaatggaag gcgctgaaca tccacacaag gagaacactg
    38281 gcggcaatca gcatcacgat agcgataatg aaactggcga gacggcagat cactcaatta
    38341 aggtgaacgg tcatcaagaa atcacatcca ccagcaggac gtgtgaccat ctaatgatcg
    38401 accttgaaac catgggaaaa aatcctgatg ccccgatcat ctcaataggt gcaatatttt
    38461 tcgatccgca aaccggagat atgggaccgg aatttagtaa gactatcgat ctggaaactg
    38521 ctggcggagt cattgatcgg gacaccatta aatggtggct taagcaatca cgcgaagcgc
    38581 aatctgccat tatgaccgat gaaatcccgt tagatgatgc actgttacaa ttgcgggaat
    38641 ttatcgacga aaactccggt gaattttttg ttcaggtctg gggaaatgga gccaacttcg
    38701 acaacacgat tttgcgccgt tcatacgaac ggcaggggat cccctgcccg tggcgttact
    38761 acaacgatcg cgatgtacgc acaatcgttg agctggggaa agccatagac ttcgatgcca
    38821 gaacggctat tccattcgaa ggtgagcgcc ataatgcact tgatgacgcc cgttaccagg
    38881 caaaatacgt ttcagttatc tggcaaaaac tgatcccgag tcaggctgat ttttaatgtt
    38941 caaccgtcgc cagttgtcgt tgatattctg caactggcgc gttccggagt gatagccatg
    39001 agcgaacagt acctgataac gctcgacgag tggaaaccaa aacggttcag tctcccaata
    39061 acaaacacta ccctggtgaa atacggaaaa ctaggataca tcgttccaag gccacaaaaa
    39121 attcgtgggc gttggctgat agatcgccga gcagtatttg ttgggcctgg tgaaacggga
    39181 attgcgccgg aaattcatac tggcgatgat gatgcactga aggagatttt aactcatgtc
    39241 accgaggcca cgaaaaaaca gcactgacgt agccggtctt tacgaaaagt ttgatcgcag
    39301 aactggcaga gtttactacc agtataaaaa tcctgtgact ggaaaatttc acggactcgg
    39361 aacagacaaa ggtaaggcag aaaaaatcgc ttccacagcc aatcagcgaa tagctgcagc
    39421 agaagctgaa tatttcatgc gcaaaattga tgaaagtctg tcagcaacaa aacgtcgggg
    39481 tatcagatta aaggcatggg ttgatcgata tctgaaaata caggacacgc gactgaaaaa
    39541 tggagatatt gcagctacaa ctcacaaaga aaaaactcga atggctgcat acctggtttc
    39601 ccgtctggga aaccacccat tgaaagaact ggaagtaaga gactttgcat taatactgga
    39661 tgagtggctg gataaagaca tggtcagcac agcgagagta aatcgtggat tatgggttga
    39721 tatttataaa gaagcacagc atgcagggga agttcctcct ggatggaatc ctccggaggc
    39781 tacccgtaaa ccgatcccta aagtaaccag agccaggctc accatggaag actggcaaaa
    39841 aatttacaat gcaacgcctg aaaaacactt tatccgtaac gcaatgcttc ttgcgattgt
    39901 tactggtcag cgccgtgatg acatttgcca catgcgtttt tcagatgtgt ggaacgaaca
    39961 cttgcatatc acccagggaa aaaccggaat gcgtctggcg ttaccgctta cactacgctg
    40021 tgatgccatt gggataacgt taaaagaagt tattgatggg tgccgagaca gaatattaag
    40081 tccatatcta atccatagtc ggcaccagaa acaaccgaag ccgatgagta aagacaacct
    40141 gagcgactac tttgccaaag cacgggatct ggctgggata attccaccag caggaaaaac
    40201 tccgccaaca tttcatgaac aacgctctct atcagaacgg ctgtaccgtg cacagggtat
    40261 cgatacaaaa acattactag gacataaagt ccaggcaacc accgatcgct ataacgatac
    40321 tcgaggtcag gaatgggtta agttggttat ttgacaaaca ccatatggaa tatccgtcac
    40381 catctcagga aaaaagtgtt gtaaaatgcg tggcctagtt ttggggaaac gttttggaga
    40441 gattttggag aaaggaaaaa attgaataaa ttcaaaatcc tgaaagtgtc ccgccttatg
    40501 aataagaagg tggaactcga atgatcggtc gactgcttcg cggcggtttt atgaccgcta
    40561 tctacgcgta cctgtatatc ccaatcatta ttttgattgt gaactccttt aacagctcgc
    40621 gctttggcat caactggcag ggttttacca ccaaatggta tagcctgctg atgaacaacg
    40681 acagcctgtt acaggcagcg cagcattcac taacaatggc ggtgttttcg gcgacgtttg
    40741 ctacgcttat cggttcactg acggcagttg cgctgtaccg ttatcgcttt cgtggtaagc
    40801 cgttcgttag cggaatgctg tttgtggtga tgatgtcacc agatatcgtg atggcgattt
    40861 cgctgctggt gctgtttatg ctgctgggta ttcagcttgg cttctggtcg ctgctgttct
    40921 cgcatatcac cttctgcctg ccatttgtgg tggtgacggt gtattcgcgc ctgaaaggtt
    40981 ttgacgtgcg aatgctggaa gcggcgaaag atctcggtgc cagcgaattt accattctgc
    41041 gaaaaatcat tctgccactg gcaattccag cggtggcggc gggctgggtg ttaagcttta
    41101 ccctgtcgat ggacgatgtg gtagtttctt cgttcgtcac cggaccaagt tatgaaattc
    41161 tgccgttaaa aatttattcg atggtcaaag tcggcgtatc gccggaagtt aacgcgctgg
    41221 caaccatatt actggtgctg tcgctggtga tggttattgc cagccagctt attgctcgtg
    41281 ataaaacgaa aggtaacaca ggggacgtta aatgaaaaaa tggtcacgcc acctgctcgc
    41341 ggcgggtgct ctggcactgg gcatgagcgc cgctcacgcc gatgacaaca acacgctgta
    41401 tttctacaac tggaccgagt acgtgccgcc aggactgctt gaacagttca ccaaagaaac
    41461 cggtattaag gttatctatt cgacttacga gtcgaacgaa accatgtacg ccaagctgaa
    41521 aacatacaaa gacggtgcct atgatctggt ggttccttca acctattacg ttgataaaat
    41581 gcgtaaagaa gggatgatcc agaagatcga caagtcgaag ttaacaaact tcagcaatct
    41641 cgatccagac atgctcaaca agccttttga cccgaataac gactactcca ttccgtatat
    41701 ctggggtgcg acggcgattg gtgttaacgg tgatgcggtg gatccgaaat ctgtcaccag
    41761 ctgggccgat ctgtggaagc cagagtacaa aggcagcctg ctgttgaccg acgatgcccg
    41821 tgaagtgttc cagatggcgc tgcgtaagct gggctactcc ggtaacacca ccgatccgaa
    41881 agagattgaa gctgcatata acgagctgaa aaaactgatg ccaaacgtgg cagcctttaa
    41941 ctccgataac ccggcgaacc cgtacatgga aggcgaagtt aacctcggca tgatctggaa
    42001 cggttctgct ttcgttgcac gccaggcggg tacgccaatt gacgtggtgt ggccgaaaga
    42061 aggcggcatt ttctggatgg acagcctggc gatcccggca aatgccaaaa acaaagaagg
    42121 cgcgctgaaa ttgatcaact tcctgctgcg cccggatgtg gcaaaacagg ttgctgaaac
    42181 tatcggttat ccaacgccaa accttgcggc gcgtaagctg ttaagtccag aagtggcgaa
    42241 cgataaaaca ctctacccgg atgctgaaac cattaaaaat ggcgaatggc agaatgacgt
    42301 tggcgcagcc agcagcattt atgaagagta ttatcagaag ctgaaagcag gacgttaatt
    42361 cagcaagcgg gcggtggtat taccgcccgt tttttagtta gcaaggatgt ggctaatgag
    42421 tcaggacagt aaagttttct ttcgtatatt cctcggtatc ggtctggtac tgatcctcat
    42481 ttctgttgtt gtcttttata accagttcac ctatagcaaa gacgcgattc ataccgaagg
    42541 cgtcattgtt gataccgtct ggcactccag tcattctcat cgcacgggta aagatggttc
    42601 gtggtatccc gtcgttgcct ttcgaccgac gccagattac acgctaattt tcaattcgag
    42661 tatcggcagc gatttttatg aagacagcga aggcgataaa gttaatgttt attattctcc
    42721 cgggcatcct gaaaaggctg agataaataa cccgtgggtt aattttttta aatgggggtt
    42781 tatcggcatt atgggcgtta tttttatcgc cgtcggttta ttaataagta tgccctcctc
    42841 taaaaaatca cgcaggaaac ggaagtcccg cccatgaaaa aattcattat actgctcagt
    42901 ttactgatac tcctgcctct gacagcagcc agcaagccat taattccaat aatgaagaca
    42961 ctttttacgg acgttaccgg tactgtacca gatgctgaag agatcgcgca taaagccgag
    43021 ctttttcgcc aacaaacggg aattgcaccg tttattgtgg ttttacccga cattaataat
    43081 gaagccagtc tcagacaaaa tggtaaagcg atgctggcgc atgcgtcatc ttcattgagt
    43141 gatgtaaaag gaagtgttct gttactattt actacccgcg aaccacggtt aattatgatc
    43201 accaacggcc aggttgaaag tggtctggac gataaacatc tcggccttct gatagaaaat
    43261 cacacgctgg cttatttaaa tgcagatctc tggtatcagg gaatcaataa tgcattggct
    43321 gttctacaag cacagatatt aaaacaatcg acgccgccac taacgtatta tccgcatcca
    43381 ggacaacagc atgaaaatgc tccccccggc agcaccaaca cattaggttt tatcgcctgg
    43441 gctgcgacgt ttatcttatt ttccaggatc ttttactaca cgactcgttt tatttatgcg
    43501 ttaaaatttg cagtggcgat gactattgcc aatatgggtt atcaggcttt atgtttgtat
    43561 atcgataata gctttgcgat taccagaata tcgccactct gggcagggct aattggtgtc
    43621 tgtacgttta ttgccgcatt gttattgacg agtaaacgat aaaagaggcc ggaaaagtgc
    43681 gcgtgtatta tgccggatgg ggcgcgaacg ccttatccgg cccacaaaac ccgcaaattc
    43741 aattaattgc gtccccttgc aggcctgata agcgtagtgc atcaggcaat gcttcccgct
    43801 tttaatccct tcagcaactt ttcaacaaac tcaggcacca cctggcttgc cgggccgtaa
    43861 tatttctcgg caaattcatt accaacctga ctcggttcaa gattcagttc cacggtgtgc
    43921 gcgccatgca gtttcgcttc gtgaacaaac ccagccgccg gataaacatg cccggatgtg
    43981 ccaatggcaa tgaaaatatc ggccatcgac aacgccatat aaattgcatc catgccgagt
    44041 ggcatttcgc caaaccacac tacgtgcggg cgcaagggtg ccggaaactg gcaacaatgg
    44101 catttatctt ctggggtaac gtctcctgtc cagtcgagaa cctgaccact ttgtgaacaa
    44161 cgcactttca gcagttcccc atgcatatga atcacattgg tattacctgc gcgttcatgc
    44221 aggttgtcga tattctgcgt caccagcaaa aagcgatcgc cgagggcgtc ttgcagttta
    44281 gccagcgcaa gatgcgcggc gttaggctga atttctggct gctgcagctg tcgacgacgg
    44341 gcgttataaa acgcttgcac cagttcagga tcgcgatcga aaccttccgg cgttgccaca
    44401 tcttcaaccc gatgttcttc ccacaggcca tctgcggcgc gaaaggtacg aatacctgat
    44461 tccgcagaaa ttcctgcccc tgtcagtacg agtactcttg gtttttccat tgcttccggc
    44521 accactttat ctctgaaaaa aatacgctga cgcaaacgct cgcgcaggcg gcgtttattt
    44581 ttacgaaaac gacttaaccg atgaccccga cgcgacagca tagcaacctc tgttgtttaa
    44641 tcggttagat gtaggaaggc cgcaccacgc attcctcccg catcaccgtg gcgcgcgcgt
    44701 tcaatgcgcg gaacacgagc tacaggtaag agatgacgag gcagcctgtc cgccagttgc
    44761 gttgtgattg ccgggaaatt cgataagcca ccaccaatga cgaccaggtc agggtcaacg
    44821 atggtcagga tatttcccag acaaaccgct aataaatcca gataacgctc aacgtgcgcc
    44881 cttgcctgct catcgccttg atcataaagc gcaataattt cgggagcctg caacggttga
    44941 tgataatagt gttgatacag ccacgcaaaa ccgcgaccag acagataatt ttcaatgcag
    45001 ccatgctgac cacagccgca gcggcgtaac gggaaatcca accccatcat ggttaacgca
    45061 tcaaccggca gacgcatatg gccaaactcg ccggtaatgt agcttttacc ggtaatcggt
    45121 ttgccgttga aaatcagccc gccgccaaca ccggtgccga gaatcaaccc catcaccagt
    45181 ggatattgag taaattcatc atcccaggct tctgaaaggg caaaacagtt ggcatcgtta
    45241 tcaaggcgta catcgcgatc aagacgtgcg ctcaggtcgg cacgcagcgg tttaccgctg
    45301 gcagcgggga cattggcggc atacagcgta ccatcttctg tttccggcat tcccggaata
    45361 ccgatgccga cagaaccttt acagccaaaa cgttggtcag cttcagctac cagctcacac
    45421 actgcatcta aaaatgcgtc atagctgtca cgcggtgtcg gcacccgctt ttcccactgc
    45481 aactgccgac cgctatcaaa cacgccaagc gcaatttttg ttccaccaat atcaaacccg
    45541 taatacattg ccgctccttg ttttaatgta ctgcctttac tggccgctaa ggactcgcgc
    45601 agggtcaata ttactggcgc gccgcgccgg ataccaactt gccaaaagac tcagcaacaa
    45661 tgctgtgacc agtacgtaga agacgtccag ccagtgcaat tccgatggca ggaaatcaat
    45721 aaaatagata tcgctggaga ggaactgatg accgatcaac ttttcaatcc actcaataat
    45781 cggggtaagt tgcagtgaaa ccactacgcc gataatcaca ccacacaggc tgccgaacag
    45841 ccctgccagc aatccatacc agacaaagat ggcgcgaatt aaaccatctt tcgcccccag
    45901 cgttcttaat actgcgatat cgccactctt gtctttcacc gccatcacta aggtggagac
    45961 gatgttgaaa caggccacgc caatcaccag taccatcgcc agatacataa tggcgcggat
    46021 catttggata tcgcgataca tatagccgta agtaccaatc cagcttttaa tataaacata
    46081 gctgttggtc acttcacccg catcgcgtac cagcttattg gcgttgaaaa catccgtcat
    46141 tttaagggca atacctgaca cgctggaacc catatcaaga tattgttggg catccgccag
    46201 cgggatcatg gcaaaactgt gatcgagttg accactcaac tgcaaaatac cggcaacgtg
    46261 caaacgcaca cgttttggct gcatcagttt atgctcggga ttcgagttgg ggatcataat
    46321 cgacacccaa tccccctgct tcactttcag cgcatccgcc acgcctttgc cgatgataat
    46381 ttgctgttcg cccgctttaa aattgcgcca cgcatcgccc tggacaaacg agggtaatgc
    46441 gctcagacgc tgttcctgtt gcgggttaac gcccttcacc tggattgcgc gaagattcgc
    46501 gccactttcc accagcccgg tgaaattgat atacggcgcg gcagcggcaa tacccggcac
    46561 tttttgcacg tgatccagtg cttcctgcca gttagtccac ggctgatcca ccgcctcgat
    46621 ttcaccatgc ggcaccaccg ccagaatacg gttgttcagt tcgcgttcaa agccgttcat
    46681 cgcgcttaag ccgacgatca ataccgccac gccgagggca atgccaatgg tagaaataac
    46741 ggagatcagc gacaccatgc cgccgcgccg ccgtccgcga ctaaaacgca ggccaattaa
    46801 taacgataac ggcatcgcca ttactccgcc cccatcaggc tcagttccgc cgtcagacga
    46861 ccatcacgca tttctaactg gcggctcata cgtttcgcca gttgcaggtc gtgagtaacc
    46921 accaggaagg cggtgccctg caagcgattc aattccccaa gcaactggaa gatgctgtcg
    46981 gcgttacgcg catcgaggtt accggtaggt tcatccgcca gtaccaggcg cgggttattc
    47041 accagcgcac gggcaatcgc cacacgctgg cgttcgccgc cagaaagttc agatgggcgg
    47101 tgattcgcac gatgatccag ccccaccgct tttaacatct caagtgcacg gctgttgatt
    47161 tcagcgggct ttttcttgcc aatcagcagc ggcatagcca cgttttccag ggcggtaaaa
    47221 tccggcagca ggtggtgaaa ctgataaata aagcccagct tctggttgcg cagttcagct
    47281 ttcgctgccg acgacagttt gctcattggc tgaccattaa aaatcacatc gccggaggtt
    47341 ggcgtatcca gcccgcccag caggtgcagc aaggtacttt taccggaacc agagctaccg
    47401 acgatcgcca tcatttcacc ttcgccgacg ctgaaactga cattgtgcag cacatcggtt
    47461 tgcacactgc cttcctgata gcgtttgcac aggttgtcgc attgcaacag gatcttattc
    47521 ataacgtaaa gcctcagcgg gttgagtggc ggcagcgcgc catgaagggt aaagcgtaga
    47581 cagcagcgcg atagccatcg ccaccagcgc aataacaatg acctgtaaag gttcgatagc
    47641 caccggcagc gccgcgccat caagcaggac gccgattatc ggcatcagat tatttaactg
    47701 gctggcaagc agggcgccaa gcgccgctcc gaggatcgca ccgataatcc cggcgctggc
    47761 cccttgcacc ataaagacca tcatgatttg tcgcggagtt aagccttgcg tttgcaggat
    47821 cgctacttcg ccctgcttct ccattaccat cagccctagt gaggtaataa tgttaaacgc
    47881 cgcaacggcg acaatcaggc tcagcagtaa acccatcata tttttttcca tgcgtacggc
    47941 ctggaacaac tcgcctttac gatcacgcca gtcctgccat ttgctgcctt caggcagttt
    48001 ttgctgactt aatgagtcga ctttcagcgg ctcatccagc cacaaacgcc agccggtaat
    48061 attgcctgcc ggataacgca tcagacgcga ggcatcctca atattcacca gcatttcata
    48121 gccatcgact tcactgttgg cggcgaaagt gccaatcaca ttgaacaggc gctggcttgg
    48181 aatacgcccc atcggcgtga actggctggc agatggtacc atcacgcgga tttgatcacc
    48241 gcgattaacg cctagctgtg aggcaagttg ttcgccgagg atgacattat atttccccgg
    48301 ctcgaggtca gtttgtttca cattgaccag atacggtgta agtggatctt tttgcgccgg
    48361 gtcgataccg agcatcaccc cgaccgccac gctgcgcgcg ctttgcagta ccacatcacc
    48421 ggtagtaata ggtgcgacgc gattaacgcc gtccagtttg actgccgttt ctgggagttg
    48481 ctgcgggtta agagagccat gctcagaaga gagaattgcc tgtggcatca ggccaaggat
    48541 gttgttttgc agctcgcgct caaagccgtt catcactgac aatactgtga ccagcgccat
    48601 caccccgagg gtaatgccga tggtagaaag ccaggagacg aaacgaccga agcgatccgc
    48661 tgcacgccca cgcatgtaac gcaggccaat aaatagagcg acaggttggt acatgaaatc
    48721 cgtctggttg ctgtagcaaa gacacgagta tataagcgaa agcaagatgg gtaaacgtct
    48781 gaactgtaag tgatcgtcag ggctaatctg aaaagccccc gtaaatcaat cggctaaatt
    48841 gccatgtttt atcatcaatc ttgccgcctg atcttaatct gaaaaatcat ccaatacaga
    48901 cagataccca ttacacctcg ggtcataacc cgcaggatca accgcatgta aattaaaaaa
    48961 gagcgtgttg tcctgatgaa acaaaaagag ctatggatta accagatcaa agggttatgt
    49021 atttgtctgg tggtgattta tcactcggtc attacctttt atccgcatct gaccactttt
    49081 cagcatccgt tatcggaagt cctgagcaaa tgctggatct atttcaatct ttaccttgcc
    49141 ccctttcgta tgccggtttt tttctttata tccggctatt tgattcgccg ctatatcgac
    49201 agcgtaccgt ggggaaattg tctcgataaa cggatctgga acatcttctg ggtgctggcg
    49261 ctttggggcg tggtgcagtg gctggcgtta agtgcgctga accagtggct ggcacctgag
    49321 cgcgatttaa gcaatgcctc caatgccgct tatgccgatt ccaccggtga gttcctgcac
    49381 gggatgatca ccgccagcaa cagcttgtgg tatctgtatg cgttaattgt ctatttcgtg
    49441 gtatgtaaaa tttttagccg tctggcgctg ccactattcg ccttgtttgt actgctgagt
    49501 gtggcggtta atttcgttcc cacgccgtgg tggggaatga acagtgtgat ccgcaatttg
    49561 ccttattaca gccttggcgc atggtttggc gcaacaataa tgacctgtgt taaagaggtg
    49621 ccgttgcgcc gccatctgct gatggcttct ttgcttaccg ttctggcggt cggtgcctgg
    49681 ttgtttacta tctcgctgct gttgtcgctg gtatcgattg tggtgatcat gaagctgttt
    49741 tatcaatacg agcaacgatt cggtatgcgc tccaccagcc tgctgaatgt gattggctcc
    49801 aacaccattg ctatctacac cacccatcgc attctggttg aaatattcag cttaactctg
    49861 cttgcgcaaa tgaacgcagc acgctggtcg ccgcaagtcg aactgacact cctgctggtt
    49921 tatccctttg tcagtttgtt catctgtact gttgcgggct tgctggtaag aaaactttca
    49981 cagcgtgcat tcagcgatct gttgttctcc ccgccttcac tgcccgctgc cgtcagttac
    50041 tcccgctaag ccatcgcccc agccggggcg attcaatttg ctaaaccatg tcgattacgg
    50101 ataatgaaca gcattgctta tcagagatat gcccccatat gttgaggcat atcctaacga
    50161 gaatctgaca accgttatgc ctgaacaata tcgttatacg ctgcccgtca aagcgggtga
    50221 gcagcgtctg ctgggcgagt taaccggcgc agcctgtgca acgctggtag cggaaattgc
    50281 cgaacgtcac gccggtccgg tggtactcat tgcaccagat atgcaaaatg ctctgcgttt
    50341 gcatgatgaa atcagccagt ttaccgatca aatggtgatg aatctggcgg actgggaaac
    50401 tcttccctac gacagttttt cgcctcatca ggacattatc tcctcgcgcc tttccaccct
    50461 ttaccagcta ccgacgatgc agcgtggcgt actgattgtt ccggtgaata cgcttatgca
    50521 gcgcgtttgc ccacacagtt ttctccacgg tcatgcgctg gtgatgaaaa aaggtcagcg
    50581 cctgtcacga gatgcattac gaacccaact ggacagcgcc ggttatcgcc atgttgacca
    50641 ggtgatggag cacggcgaat acgccacgcg cggcgcgttg ctggatctct tcccgatggg
    50701 gagtgagctg ccttatcgtc ttgatttctt tgatgatgaa atcgacagcc tgcgggtgtt
    50761 tgacgtcgac agccagcgca cgctggagga agtagaagcg atcaatctgc tgcccgcgca
    50821 cgaatttccg accgataaag cggcaattga actgttccgc agccagtggc gcgatacctt
    50881 cgaagtgaag cgcgatccag aacatattta ccagcaagtg agtaaaggca cattacctgc
    50941 cgggatcgag tactggcagc cattgttctt cagcgaacca ctgccgccgc tgttcagtta
    51001 tttccctgcc aataccttgc tcgtgaatac tggcgatctg gaaaccagtg ccgaacgttt
    51061 ccaggctgac acgctggcgc gttttgagaa tcgcggcgtc gatccgatgc gcccgctgtt
    51121 gccaccacaa tcgctctggc tgcgggtgga cgagctcttc tcagagctga aaaactggcc
    51181 ccgggtgcag ctaaaaactg aacatttacc gacaaaagcc gcgaatgcca atttaggttt
    51241 ccagaaactg ccagacctgg ccgttcaggc acaacaaaaa gcgccgctgg atgcgctgcg
    51301 taagttcctc gagactttcg acggtccggt ggtgttctcg gtagaaagtg aaggtcgccg
    51361 tgaagcgctg ggtgaactgc tcgcacgaat taaaattgct ccgcaacgca ttatgcgtct
    51421 tgatgaagcc agcgaccgtg ggcgttatct gatgattggc gctgccgaac atggttttgt
    51481 cgatacggtg cgtaatctgg cgctgatttg cgaaagcgat ctgctcggtg aacgcgttgc
    51541 ccgtcgtcgt caggattctc gccgcaccat caaccccgat acactgatcc gtaaccttgc
    51601 ggaactgcat attggtcagc cggtggtcca tctggagcac ggcgtcggtc gttatgccgg
    51661 aatgaccacg ctggaagcgg gtggcattac tggcgagtat ctgatgctca cctatgccaa
    51721 cgacgccaaa ctgtatgttc cggtgtcgtc actgcatctg attagccgtt acgcaggtgg
    51781 cgcggaagaa aacgccccgc tgcataaact tggcggcgat gcgtggtcac gcgcgcggca
    51841 gaaagcggcg gaaaaagtgc gtgatgtggc ggcggaattg ctggatatct acgcgcaacg
    51901 cgccgccaaa gagggcttcg cgtttaaaca cgatcgtgag cagtatcagt tgttctgcga
    51961 cagcttcccg tttgaaacca cgccggatca ggcgcaggcc attaatgcgg tacttagcga
    52021 catgtgtcag ccgctggcaa tggatcgtct ggtgtgcggc gatgttggct ttggtaaaac
    52081 agaagtggcg atgcgcgcag ctttcctggc agtagataac cacaagcagg tggcggtgct
    52141 ggtgcctacc acccttctcg cgcagcagca ttacgacaac ttccgcgacc gtttcgccaa
    52201 ctggccggta cgtatcgaaa tgatctcccg tttccgcagc gccaaagagc agacgcaaat
    52261 ccttgcggaa gtggcggaag ggaaaatcga tattctgatc ggtacgcaca aactgctgca
    52321 aagtgacgtc aagtttaaag atttaggcct gctgattgtc gatgaagaac accgcttcgg
    52381 ggtgcgtcat aaagagcgca ttaaagcgat gcgcgcgaac gtggatattc tgacgcttac
    52441 tgcaacgccg atcccacgta cgctgaatat ggcaatgagc ggaatgcgtg acctgtcgat
    52501 tatcgccacg ccgcccgccc gtcgtctggc agttaaaacc tttgtccgtg agtatgacag
    52561 catggtggtc cgggaggcga tcctgcgtga aattttgcgc ggaggacagg tttattatct
    52621 ctacaatgat gtggaaaaca ttcagaaagc cgccgaacgg ctggcagaac tggtgccaga
    52681 agcgcggatc gccatcggtc acgggcagat gcgcgagcgc gaactggaac gggtgatgaa
    52741 tgatttccat catcaacgtt tcaacgtgct ggtttgtaca accattatcg aaaccgggat
    52801 cgacatcccg acagccaaca ctattatcat tgaacgcgcg gatcacttcg gtctggcgca
    52861 gctgcaccag ttacgcggtc gcgtcggacg ttcgcatcat caggcatatg catggttgct
    52921 gacaccgcat ccaaaagcga tgactaccga tgcacaaaaa cgtcttgaag caattgcctc
    52981 gctggaagat ctcggggcag gttttgcgct ggcaacgcac gatctggaga ttcgcggcgc
    53041 gggtgaactg cttggcgaag aacaaagcgg ctcaatggaa accatcggtt tctcgctgta
    53101 tatggagttg ctggaaaacg ccgtcgatgc actgaaagcc ggacgcgagc cgtcgctgga
    53161 agatctcacc agccagcaaa cagaagtcga gctgcggatg ccgtcgctat tgccagatga
    53221 tttcatccct gacgtgaaca cgcgtctgtc gttctacaaa cgtattgcca gcgccaaaac
    53281 ggaaaacgaa ctggaagaga tcaaagtcga gcttatcgat cgcttcggcc tgctgccaga
    53341 tccggcgcgt accctgctgg atattgcccg tctgcgccag caagcgcaga aactggggat
    53401 caggaagctg gaaggtaatg agaaaggcgg ggtgatcgaa tttgccgaga agaatcacgt
    53461 taatccggcc tggttgattg gtttgctgca aaaacagccg cagcattacc gccttgatgg
    53521 tccgacgcgc ctgaaattta ttcaggattt gagtgagcgg aaaacgcgta tcgaatgggt
    53581 acgccagttt atgcgtgaac tggaagagaa cgcgatcgct taatggtaaa tcgggggcgt
    53641 ttctgcgccc ccatctgcaa catttacaaa ttctttgcac ttccctgcac tatccgacac
    53701 tgtcaccatc cataattcag gcttatctgt ttattacaat aaccttatat ttattatgga
    53761 tttttggtga tgatcaaaac gcgtttttct cgctggctaa cgttttttac gttcgccgct
    53821 gccgtggcgc tggcgctacc ggcaaaagcc aacacctggc cgctgccgcc agcgggcagt
    53881 cgtctggttg gcgaaaacaa atttcatgtg gtggaaaatg acggtggttc tctggaagcc
    53941 atcgccaaaa aatacaacgt cggctttctc gctctgttac aggctaaccc cggcgttgat
    54001 ccttacgtac cgcgcgcggg cagcgtgtta acgatcccgt tgcaaaccct acttccagat
    54061 gcgccgcgcg aaggcattgt gatcaacatt gcggagctgc gtctctatta ctacccgccg
    54121 ggtaaaaatt cggtaaccgt gtatccaata ggtattggtc agttaggtgg tgacacgctg
    54181 acaccgacaa tggtgaccac cgtttcagac aaacgtgcaa acccaacctg gacgccaacg
    54241 gcaaacatcc gcgcccgtta taaagcacag ggaattgagt tgcctgcggt agtgccggct
    54301 ggaccggata acccaatggg ccatcatgcg attcgtctgg cggcctatgg cggcgtttat
    54361 ttgcttcatg gtacgaacgc cgatttcggc attggcatgc gggtaagttc tggctgtatt
    54421 cgtctgcggg atgacgatat caaaacactc tttagccagg tcaccccagg caccaaagtg
    54481 aatatcatca acactccgat aaaagtctct gccgaaccaa acggtgcgcg tctggttgaa
    54541 gtacatcagc cgctgtcaga gaagattgat gacgatccgc agctgctgcc aattacgctg
    54601 aatagcgcaa tgcaatcatt taaagatgca gcacaaactg acgctgaagt gatgcaacat
    54661 gtgatggatg tccgttccgg gatgccggtg gatgtccgcc gtcatcaagt gagcccacaa
    54721 acgctgtaaa gcccggataa aaaaatcccc gcgacacggc atgtcgcggg gaaaaaatca
    54781 gcagtagcag gcattaatga gggttaatgc ttatttataa attactgctg ttccatggag
    54841 ggtattcgga ccggttacag aagtaatacg gaaagatttt gcgcccatct catccgcttt
    54901 ttgcgccagc tgctcttcca gcgatcccag atttgtcccc gcgttagcac tgattgtacc
    54961 gactttttgt tggccttctg gcgttgactg aacttcgaca gccgcaaagc tggcaaatga
    55021 catggagctt aaaatcgccg cagcgatgag ggtttttacg tttttcataa tagtggcctt
    55081 atgcagatga atgacgtcgc aagcaattac ttaacgatcg at
//
LOCUS       DACAOP010000019        55040 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.019, whole genome shotgun sequence.
ACCESSION   DACAOP010000019 DACAOP010000000
VERSION     DACAOP010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 55040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55040
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.019"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            396..890
                     /gene="lrp"
                     /locus_tag="IT892_001327"
     CDS             396..890
                     /gene="lrp"
                     /locus_tag="IT892_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-responsive transcriptional regulator
                     Lrp"
                     /protein_id="HAP3134560.1"
                     /translation="MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTP
                     CLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEE
                     IQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
                     IKTR"
     gene            1025..5014
                     /gene="ftsK"
                     /locus_tag="IT892_001328"
     CDS             1025..5014
                     /gene="ftsK"
                     /locus_tag="IT892_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP3134561.1"
                     /translation="MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSF
                     NPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQS
                     SDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
                     SGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYE
                     DDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDE
                     EITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWA
                     APVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQ
                     YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQ
                     TEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARERE
                     QLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAA
                     TVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKA
                     REAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAA
                     EAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQ
                     QPQQPVAPQQQYQQPQQPVPPQPQYQQPQQPVAPQPQYQQPQQPVAPQQQYQQPQQPV
                     APQQQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPV
                     DTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLA
                     RSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDI
                     AGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELS
                     VYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRM
                     MRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKAR
                     AAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDM
                     LYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGA
                     EELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNR
                     EVLAPPPFD"
     gene            5173..5784
                     /gene="lolA"
                     /locus_tag="IT892_001329"
     CDS             5173..5784
                     /gene="lolA"
                     /locus_tag="IT892_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HAP3134562.1"
                     /translation="MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQK
                     VTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWL
                     KDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQ
                     FSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK"
     gene            5795..7138
                     /locus_tag="IT892_001330"
     CDS             5795..7138
                     /locus_tag="IT892_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAP3134563.1"
                     /translation="MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRA
                     IEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNR
                     NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
                     LLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMM
                     ADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALY
                     WYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIA
                     QAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYA
                     HDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR"
     gene            7229..8521
                     /gene="serS"
                     /locus_tag="IT892_001331"
     CDS             7229..8521
                     /gene="serS"
                     /locus_tag="IT892_001331"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAP3134564.1"
                     /translation="MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKT
                     ENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALT
                     IPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
                     RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLF
                     HTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGR
                     DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMG
                     FGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSG
                     LAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG"
     gene            8760..11204
                     /gene="dmsA"
                     /locus_tag="IT892_001332"
     CDS             8760..11204
                     /gene="dmsA"
                     /locus_tag="IT892_001332"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415414.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit A"
                     /protein_id="HAP3134565.1"
                     /translation="MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAH
                     AVDSAIPTKSDEKVIWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGDDNYDGLHQVR
                     ACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGN
                     ESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYG
                     GWADGNSPSDIENSKLVVLFGNNPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTD
                     TGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCVGYDEKTLPASAPKN
                     GHYKAYILGEGPDGVAKTPEWASQITGVPADKIIKLAREIGSTKPAFISQGWGPQRHA
                     NGEIATRAISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLENPIQTSISMFMWTD
                     AIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDKKCEL
                     IVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFNDQVIKPRFECKTI
                     YEMTSELAKRLGVEQQFTEGRTQEEWMRHLYAQSREAIPELPTFEEFRKQGIFKKRDP
                     QGHHVAYKAFREDPQANPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTPGF
                     ESYQDPLNKQYPLQLTGFHYKSRVHSTYGNVDVLKAACRQEMWINPLDAQKRGIHNGD
                     KVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDAKRVDKGGCINVLTTQRPSPL
                     AKGNPSHTNLVQVEKV"
     gene            11215..11832
                     /gene="dmsB"
                     /locus_tag="IT892_001333"
     CDS             11215..11832
                     /gene="dmsB"
                     /locus_tag="IT892_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HAP3134566.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            11834..12697
                     /locus_tag="IT892_001334"
     CDS             11834..12697
                     /locus_tag="IT892_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HAP3134567.1"
                     /translation="MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRV
                     IACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGW
                     LLAMLKKLSPALRTLWLIVTMVLGVIFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMF
                     MGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVVSVMQGAELATIHSSVQQAAA
                     LVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYG
                     LHMTVGMAVAS"
     gene            complement(12732..13358)
                     /locus_tag="IT892_001335"
     CDS             complement(12732..13358)
                     /locus_tag="IT892_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP3134568.1"
                     /translation="MTKPYVRLDKNDAAVLLVDHQAGLLSLVRDIEPDKFKNNVLALG
                     DLAKYFNLPTILTTSFETGPNGPLVPELKAQFPDTPYIARPGNINAWDNEDFVKAVKA
                     TGKKQLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNEITRHSAWDRLSQAGA
                     QLMTWFGVACELHRDWRNDIEGLATLFSNHIPDYRNLMTSYDTLTKQK"
     gene            13672..14820
                     /locus_tag="IT892_001336"
     CDS             13672..14820
                     /locus_tag="IT892_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3134569.1"
                     /translation="MSTYTQPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVG
                     VVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRF
                     VAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSV
                     LPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITSMLKLRQARLGVNGCIISGIVLGS
                     LYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVI
                     LGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGS
                     LLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV"
     gene            15030..16460
                     /locus_tag="IT892_001337"
     CDS             15030..16460
                     /locus_tag="IT892_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415419.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP3134570.1"
                     /translation="MAGNVQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSW
                     VFIFALYFTPYALIVGQLGSTFKDGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLA
                     QKPQAILIALGWAMKGDGSLIKEYSVVALQGLTLVLFIFFMWVASRGMKSLKIVGSVA
                     GIAMFVMSLLYVAMAVTAPAITEVHIATTNITWETFIPHIDFTYITTISMLVFAVGGA
                     EKISPYVNQTRNPGKEFPKGMLCLAVMVAVCAILGSLAMGMMFDSRNIPDDLMTNGQY
                     YAFQKLGEYYNMGNTLMVIYAIANTLGQVAALVFSIDAPLKVLLGDADSKYIPASLCR
                     TNASGTPVNGYFLTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAF
                     IAVVRLAQKYKPEYVFIRNKPLAMTVGIWCFAFTAFACLTGIFPKMEAFTAEWTFQLA
                     LNVATPFVLVGLGLIFPLLARKANSK"
     gene            complement(16461..17369)
                     /locus_tag="IT892_001338"
     CDS             complement(16461..17369)
                     /locus_tag="IT892_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3134571.1"
                     /translation="MRMNMSDFATFFAVARNQSFRAAGDELGLSSSAISHSIKTLEQR
                     LKIRLFNRTTRSVSLTEAGSNLYERLRPAFDEIQIMLDEMNDFRLTPTGTLKINAARV
                     AARIFLMSLLVGFTREYPDIKVELTTDDSLVDIVQQGFDAGVRLSCIVEKDMISVAIG
                     PPVKLCVAATPEYFARYGKPRHPHDLLNHQCVVFRYPSGKPFHWQFAKELEIAVAGNI
                     ILDDVDAELEAVLMGAGIGYLLYEQIKEYLDTGRLECVLEDWSTERPGFQIYYPNRQY
                     MSCGLRAFLDYVKTGQICQSQRHRPQ"
     gene            17469..18059
                     /locus_tag="IT892_001339"
     CDS             17469..18059
                     /locus_tag="IT892_001339"
                     /EC_number="1.6.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H oxidoreductase"
                     /protein_id="HAP3134572.1"
                     /translation="MQSERIYLVWAHPRHDSLTAHIADAIHQRAMERKIQVTELDLYR
                     RNFNPVMTPEDEPDWKNMDKRYSPEVHQLYSELLEHDTLVVVFPLWWYSFPAMLKGYI
                     DRVWNNGLAYGDGHKLPFNKVRWVALVGGDKESFVQMGWEKNISDYLKNMCSYLGIED
                     ADVTFLCNTVVFDGEELHASYYQSLLSQVRDMVDAL"
     gene            complement(18141..18881)
                     /gene="pflA"
                     /locus_tag="IT892_001340"
     CDS             complement(18141..18881)
                     /gene="pflA"
                     /locus_tag="IT892_001340"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase 1-activating protein"
                     /protein_id="HAP3134573.1"
                     /translation="MSVIGRIHSFESCGTVDGPGIRFITFFQGCLMRCLYCHNRDTWD
                     THGGKEVTVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKEGIHT
                     CLDTNGFVRRYDPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANK
                     NVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELGKHKWVAMGEEYK
                     LDGVKPPKKETMERVKGILEQYGHKVMF"
     gene            complement(19073..21355)
                     /gene="pflB"
                     /locus_tag="IT892_001341"
     CDS             complement(19073..21355)
                     /gene="pflB"
                     /locus_tag="IT892_001341"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAP3134574.1"
                     /translation="MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFL
                     AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQT
                     EAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
                     RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTI
                     RLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMS
                     FGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIW
                     ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS
                     IDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG
                     VDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYE
                     ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ
                     FGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR
                     RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR
                     KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF
                     NSLTKEQQQDVITRTFTQSM"
     gene            complement(21410..22267)
                     /gene="focA"
                     /locus_tag="IT892_001342"
     CDS             complement(21410..22267)
                     /gene="focA"
                     /locus_tag="IT892_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocA"
                     /protein_id="HAP3134575.1"
                     /translation="MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVF
                     ISIAFVFYITATTGTGTMPFGMAKLVGGICFSLGLILCVVCGADLFTSTVLIVVAKAS
                     GRITWGQLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKVHHT
                     FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIP
                     MGIVIRDFASPEFWTAVGSAPENFSHLTVMNFITDNLIPVTIGNIIGGGLLVGLTYWV
                     IYLRENDHH"
     gene            complement(22673..24433)
                     /locus_tag="IT892_001343"
     CDS             complement(22673..24433)
                     /locus_tag="IT892_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415425.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     accessory protein YcaO"
                     /protein_id="HAP3134576.1"
                     /translation="MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVW
                     SVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVH
                     YPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTR
                     QSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPE
                     IPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGA
                     HPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDL
                     FKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSD
                     IYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLG
                     LATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQ
                     TLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAH
                     QSLLKAYEKLQRAKAAFWAK"
     gene            24563..25255
                     /locus_tag="IT892_001344"
     CDS             24563..25255
                     /locus_tag="IT892_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAP3134577.1"
                     /translation="MKAFDLHRMAFDKVPFDFLGEVALRSLYTFVLVFLFLKMTGRRG
                     VRQMSLFEVLIILTLGSAAGDVAFYDDVPMVPVLIVFITLALLYRLVMWLMAHSEKLE
                     DLLEGKPVVIIEDGELAWSKLNNSNMTEFEFFMELRLRGVEQLGQVRLAILETNGQIS
                     VYFFEDDKVKPGLLILPSDCTQRYKVVPESADYACIRCSEIIHMKAGEKQLCPRCANP
                     EWTKASRAKRVT"
     gene            25454..26542
                     /gene="serC"
                     /locus_tag="IT892_001345"
     CDS             25454..26542
                     /gene="serC"
                     /locus_tag="IT892_001345"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HAP3134578.1"
                     /translation="MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGK
                     EFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYW
                     AASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAID
                     ETPDFGADVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKA
                     NIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELL
                     YGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGM
                     RASIYNAMPLEGVKALTDFMVEFERRHG"
     gene            26613..27896
                     /gene="aroA"
                     /locus_tag="IT892_001346"
     CDS             26613..27896
                     /gene="aroA"
                     /locus_tag="IT892_001346"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAP3134579.1"
                     /translation="MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNL
                     LDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPL
                     AAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGG
                     NVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQ
                     HYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRF
                     ADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNI
                     YNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFS
                     LVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA"
     gene            28065..28829
                     /locus_tag="IT892_001347"
     CDS             28065..28829
                     /locus_tag="IT892_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706828.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HAP3134580.1"
                     /translation="MKNTKLLLAIATSAALLTGCQNTHGIDTNMAISSGLNAYKAATL
                     SDADAKAIANQGCAEMDSGNQVASKSSKYGKRLAKIAKALGNNINGTPVNYKVYMTSD
                     VNAWAMANGCVRVYSGLMDMMNDNEIEGVLGHELGHVALGHSLAEMKASYAIVAARDA
                     ISATSGVASQLSRSQLGDIAEGAINAKYSRDKESEADDFSFDLLKKRGISTQGLVGSF
                     EKLASLDGGRTQSMFDSHPPSTERAQHIRDRIASGK"
     gene            29002..29685
                     /gene="cmk"
                     /locus_tag="IT892_001348"
     CDS             29002..29685
                     /gene="cmk"
                     /locus_tag="IT892_001348"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAP3134581.1"
                     /translation="MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLA
                     LAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQ
                     VAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
                     QLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQ
                     YARQKLALA"
     gene            29796..31469
                     /gene="rpsA"
                     /locus_tag="IT892_001349"
     CDS             29796..31469
                     /gene="rpsA"
                     /locus_tag="IT892_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAP3134582.1"
                     /translation="MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKS
                     ESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAY
                     EDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
                     QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLL
                     HITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPE
                     GTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLD
                     IDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVH
                     LSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKK
                     GAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGV
                     DRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE"
     gene            31629..31913
                     /gene="ihfB"
                     /locus_tag="IT892_001350"
     CDS             31629..31913
                     /gene="ihfB"
                     /locus_tag="IT892_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HAP3134583.1"
                     /translation="MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIE
                     IRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG"
     gene            32121..34385
                     /locus_tag="IT892_001351"
     CDS             32121..34385
                     /locus_tag="IT892_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415433.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family protein"
                     /protein_id="HAP3134584.1"
                     /translation="MKITTVGVCIISGIFPLLILPQLPGTLTLAFLTLFACVLAFIPV
                     KTVRYIALTLLFFVWGILSAKQILWAGETLTGATQDAIVEITATDGMTTHYGQITHLQ
                     GRRIFPASGLVMYGEYLPQAVCAGQQWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
                     TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRD
                     TGTAHLMAISGLHIAFAALLAAGLIRSGQIFLPGRWIHWQIPLIGGICCAAFYAWLTG
                     MQPPALRTMVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPVAILSQSLWLSAAAV
                     AALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANL
                     LAIPLVTFITVPLILAAMVVHLSGPLILEQGLWFLADRSLALLFWGLKSLPEGWINIA
                     ECWQWLSFSPWFLLVVWRLNAWRTLPAMCVAGGLLMCWPLWQKPRPDEWQLYMLDVGQ
                     GLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHLDHRGGL
                     DSILHIWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSAHWPLQGSNDKGNNHSCVVK
                     VDDGTNSILLTGDIEAPAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKV
                     ALASASRYNAWRLPSNKVKHRYQLQGYQWIDTPHQGQTTVNFSAQGWRISSLREQILP
                     RWYHQWFGVPVDNG"
     gene            34422..36170
                     /gene="msbA"
                     /locus_tag="IT892_001352"
     CDS             34422..36170
                     /gene="msbA"
                     /locus_tag="IT892_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A ABC transporter ATP-binding
                     protein/permease MsbA"
                     /protein_id="HAP3134585.1"
                     /translation="MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFM
                     LSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVSGKVVMTMRR
                     RLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
                     FYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVL
                     IFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVM
                     DSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRV
                     IERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRF
                     YDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQI
                     EEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEAT
                     SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLL
                     EHRGVYAQLHKMQFGQ"
     gene            36167..37153
                     /gene="lpxK"
                     /locus_tag="IT892_001353"
     CDS             36167..37153
                     /gene="lpxK"
                     /locus_tag="IT892_001353"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HAP3134586.1"
                     /translation="MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRA
                     PVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTT
                     TAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVE
                     IVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNL
                     RTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALV
                     SAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTLLASGN"
     gene            37190..38422
                     /gene="ycaQ"
                     /locus_tag="IT892_001354"
     CDS             37190..38422
                     /gene="ycaQ"
                     /locus_tag="IT892_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix DNA-binding protein YcaQ"
                     /protein_id="HAP3134587.1"
                     /translation="MSLPHLSLADARNLHLAAQGLLNKPRRRASLEDIPATISRMSLL
                     QIDTINIVARSPYLVLFSRLGNYPAQWLDESLARGELMEYWAHEACFMPRSDFRLIRH
                     RMLAPEKMGWKYKDAWMQEHEAEIAQLIQHIHDKGPVRSADFEHPRKGASGWWEWKPH
                     KRHLEGLFTAGKVMVIERRNFQRVYDLTHRVMPDWDDERDLVSQTEAEIIMLDNSARS
                     LGIFREQWLADYYRLKRPALAAWREARAEQQQIIAVHVEKLGNLWLHDDLLPLLERAL
                     AGKLTATHSAVLSPFDPVVWDRKRAEQLFDFSYRLECYTPAPKRQYGYFVLPLLHRGQ
                     LVGRMDAKMHRQTGILEVISLWLQEGIKPTTTLQKGLRQAITDFANWQQATRVTLGCC
                     PQGLFTDCRTGWEIDPVA"
     gene            38474..38656
                     /locus_tag="IT892_001355"
     CDS             38474..38656
                     /locus_tag="IT892_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcaR"
                     /protein_id="HAP3134588.1"
                     /translation="MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPV
                     LLETEARVLTADESKS"
     gene            38653..39399
                     /gene="kdsB"
                     /locus_tag="IT892_001356"
     CDS             38653..39399
                     /gene="kdsB"
                     /locus_tag="IT892_001356"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HAP3134589.1"
                     /translation="MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAER
                     IIVATDHEDVARAVEAAGGEVCMTSADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEP
                     MIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
                     PWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYG
                     EKIHVAVAQEVPGTGVDTPEDLERVRAEMR"
     gene            39553..40446
                     /locus_tag="IT892_001357"
     CDS             39553..40446
                     /locus_tag="IT892_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbJ family phosphotransferase"
                     /protein_id="HAP3134590.1"
                     /translation="MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLM
                     VRSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMTHEEHPGPDVLLLERMRGVSVEA
                     PARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYRQHVEVLWTTLN
                     QFNNTGLTMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMV
                     GPGLMLWAPREYELFRLMDNSLAEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVN
                     TGRFSRRNFDLASKSLLPWLA"
     gene            complement(40423..41202)
                     /gene="elyC"
                     /locus_tag="IT892_001358"
     CDS             complement(40423..41202)
                     /gene="elyC"
                     /locus_tag="IT892_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope biogenesis factor ElyC"
                     /protein_id="HAP3134591.1"
                     /translation="MLFTLKKVIGNMLLPLPLMLLIIGAGLALLWFSRFQKTGKIFIS
                     IGWLALLLLSLQPVADRLLRPIESTYPTWNNSQKVDYIVVLGGGYTWNPQWAPSSNLI
                     NNSLPRLNEGIRLWRENPGSKLIFTGGVAKTNTVSTAEVGARVAQSLGVPREQIITLD
                     LPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQQEGLNPLPAPANQLAIDSPL
                     NPWERAIPSPVWLMHSDRVGYETLGRIWQWLKGSSGEPRQE"
     gene            41338..42123
                     /gene="cmoM"
                     /locus_tag="IT892_001359"
     CDS             41338..42123
                     /gene="cmoM"
                     /locus_tag="IT892_001359"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-oxyacetic acid(34)
                     methyltransferase CmoM"
                     /protein_id="HAP3134592.1"
                     /translation="MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ
                     KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA
                     QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
                     VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK
                     HQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQSKDKV"
     gene            42120..43442
                     /gene="mukF"
                     /locus_tag="IT892_001360"
     CDS             42120..43442
                     /gene="mukF"
                     /locus_tag="IT892_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukF"
                     /protein_id="HAP3134593.1"
                     /translation="MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLD
                     GEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYR
                     LTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPL
                     KYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLREL
                     QDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIG
                     YDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALR
                     DEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRA
                     RHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY"
     gene            43423..44127
                     /gene="mukE"
                     /locus_tag="IT892_001361"
     CDS             43423..44127
                     /gene="mukE"
                     /locus_tag="IT892_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukE"
                     /protein_id="HAP3134594.1"
                     /translation="MSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNH
                     AFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYL
                     YLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLN
                     RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQ
                     LNDETEENQPDSGEEE"
     gene            44127..48587
                     /gene="mukB"
                     /locus_tag="IT892_001362"
     CDS             44127..48587
                     /gene="mukB"
                     /locus_tag="IT892_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukB"
                     /protein_id="HAP3134595.1"
                     /translation="MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTM
                     AAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVV
                     GVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAM
                     EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLR
                     DYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMR
                     HANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAAS
                     DHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEV
                     DELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADCAAEWLETFQAK
                     ELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQ
                     RHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARI
                     ASLSDSVSNAREERMALCQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTS
                     SQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFG
                     GVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGD
                     PQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLS
                     ERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHE
                     NDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQ
                     FGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSY
                     SDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDT
                     KKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAE
                     MDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDL
                     RSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIR
                     TDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGL
                     QNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLN
                     PQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSIL
                     VMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPE
                     NISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTDEAPSQAS"
     gene            48848..50695
                     /gene="ldtD"
                     /locus_tag="IT892_001363"
     CDS             48848..50695
                     /gene="ldtD"
                     /locus_tag="IT892_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HAP3134596.1"
                     /translation="MLLNMMCGRRLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAV
                     SEQGEALPQAQATAIMAGIQPLPEGAAEKARTQIESQLPAGYKPVYLNQLQLLYAARD
                     MQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGY
                     LHFIANIPVKGTRWLYSSKPYALATPPLSVINQWQLALDKGQLPTFVAGLAPQHPQYA
                     AMHESLLALLCDTKPWPQLTGKATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGD
                     DTPTDAVVSPSAVTVETAETKPMDKQTTSRSKPAPAVRAAYDNELVEAVKRFQAWQGL
                     GADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNG
                     NQVLDSRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESH
                     GYTVMRGWNSREAIDPWQVDWSTITASNLPFRFQQAPGPRNSLGRYKFNMPSSEAIYL
                     HDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGDTRYVNI
                     RQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR"
     gene            50876..51424
                     /locus_tag="IT892_001364"
     CDS             50876..51424
                     /locus_tag="IT892_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbK family protein"
                     /protein_id="HAP3134597.1"
                     /translation="MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNN
                     LHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTR
                     KPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRA
                     GGVGYYPRSNFVHIDTGPARHW"
     gene            51451..52098
                     /gene="gloC"
                     /locus_tag="IT892_001365"
     CDS             51451..52098
                     /gene="gloC"
                     /locus_tag="IT892_001365"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase GloC"
                     /protein_id="HAP3134598.1"
                     /translation="MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDD
                     SGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEEC
                     QPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGR
                     SDFPRGDHNQLISSIKDKLLPLGDDVIFIPGHGPLSTLGYERLHNPFLQDEMPVW"
     gene            complement(52320..53510)
                     /locus_tag="IT892_001366"
     CDS             complement(52320..53510)
                     /locus_tag="IT892_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009653304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/tyrosine/aromatic aminotransferase"
                     /protein_id="HAP3134599.1"
                     /translation="MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTP
                     VLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPG
                     GTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFD
                     ALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFA
                     RGLEEDAEGLRAFAAMHKELIVASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMK
                     AAIRANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGA
                     NRDFSFIIKQNGMFSFSGLTKEQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAI
                     VAVL"
     gene            complement(53695..54783)
                     /gene="ompF"
                     /locus_tag="IT892_001367"
     CDS             complement(53695..54783)
                     /gene="ompF"
                     /locus_tag="IT892_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpF"
                     /protein_id="HAP3134600.1"
                     /translation="MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHY
                     FSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNK
                     TRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVAT
                     YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADR
                     TNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKT
                     QDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVD
                     YIINQIDSDNKLGVGSDDTVAVGIVYQF"
BASE COUNT        13464 a        13312 c        14629 g        13635 t
ORIGIN      
        1 ttaaatttcc cgctttataa gccgattaaa tgatgaataa acgcccctgt taatgaatat
       61 ctggcatgtt gtactaaaaa tcgatgtttt gctttgacaa tcccctggtg ttttgcgaaa
      121 acattcgagg aagaaaaaaa acagtattct tatatgcgca taaccatgca tgtaaatacc
      181 atgtttaccg tgctagtgaa atctacgtat ggcgtggaca gacgccattc gtgatgtcga
      241 tagctgccac aaggcaacgg tcttctcacc gtagacccag gcattgcgcg ccgtgaatct
      301 tcatgatttc ggtctatcgt gacgggtagc gactctgaac agtgatgttt cagggtcaga
      361 caggagtagg gaaggaatac agagagacaa taataatggt agatagcaag aagcgccctg
      421 gcaaagatct cgaccgtatc gatcgtaaca ttcttaatga gttgcaaaag gatgggcgta
      481 tttctaacgt cgagctttct aaacgtgtgg gactttcccc aacgccgtgc cttgagcgtg
      541 tgcgtcggct ggaaagacaa gggtttattc agggctatac ggcgctgctt aacccccatt
      601 atctggatgc atcacttctg gtattcgttg agattactct gaatcgtggc gcaccggatg
      661 tgtttgaaca attcaatacc gctgtacaaa aacttgaaga aattcaggag tgtcatttag
      721 tatccggtga tttcgactac ctgttgaaaa cacgcgtgcc ggatatgtca gcctaccgta
      781 agttgctggg ggaaaccctg ctgcgtctgc ctggcgtcaa tgacacacgg acatacgttg
      841 ttatggaaga agtcaagcag agtaatcgtc tggttattaa gacgcgctaa cacggaacag
      901 gtgcaaaatc ggcgtatttt gattacactc ctgttaatcc atacagcaac agtactgggg
      961 taacctggta ctgttgtccg ttttagcatc gggcaggaaa agcctgtaac ctggagagcc
     1021 tttcttgagc caggaataca ctgaagacaa agaagtcaca ttgacaaagt taagtagcgg
     1081 ccgccgcctt ctggaggcgt tgctgatcct tattgtcctg tttgccgtct ggttgatggc
     1141 tgccttacta agctttaacc cttcggaccc cagctggtcg caaacggcct ggcatgaacc
     1201 tatccataat ttaggtggga tgcccggtgc gtggttggca gatacgctgt tctttatttt
     1261 tggcgtgatg gcttacacca ttcccgtcat tattgtcggc ggttgttggt ttgcctggcg
     1321 tcatcagtcc agcgacgaat acattgatta ttttgccgtt tcgctacgca tcattggcgt
     1381 tttggcgctc atccttacct cctgtggtct ggcggcaatc aacgctgacg atatctggta
     1441 ttttgcctcc ggtggcgtca ttggcagctt actaagcact acgctacaac cactgctaca
     1501 cagtagcggg ggaactattg cgctgctctg cgtttgggca gcgggcctga cgttgttcac
     1561 cggttggtca tgggtgacca ttgctgaaaa actcggcggc tggattttaa acattcttac
     1621 cttcgccagt aatcgtaccc gtcgcgatga tacctgggtc gatgaagatg agtatgaaga
     1681 cgacgaagag tatgaagatg aaaatcacgg caaacagcat gaatcacgcc gtgcccgtat
     1741 tcttcgcggc gcgctagcgc gtcgtaaacg gttggcggaa aaattcatta atccgatggg
     1801 gcggcaaaca gacgctgcgt tgttctccgg taagcggatg gatgatgacg aagagattac
     1861 ctacactgca cgcggtgtgg ctgccgaccc ggacgacgtc ctattttcgg gcaatcgtgc
     1921 aacgcagcca gaatatgacg aatacgatcc attattaaac ggtgcgccaa ttaccgaacc
     1981 tgtcgctgta gcagctgctg ctaccacggc gacacaaagc tgggctgcgc cggttgaacc
     2041 tgtgactcag acgccgcctg ttgcctctgt tgatgttcca cctgcgcaac ctacagtagc
     2101 ctggcagcct gtaccgggtc cacaaacggg agagccggtt attgctcctg caccggaagg
     2161 ttacccacag cagtcacaat atgcgcagcc tgcagtgcaa tataatgagc cgctgcaaca
     2221 accagtacag ccgcagcagc cgtattatgc acctgcagct gaacaacctg cgcaacagcc
     2281 gtattatgcc cctgcgccag aacaaccggt ggcaggtaac gcctggcaag ccgaagagca
     2341 gcaatccact tttgctccac agtctacata ccagactgag caaacttatc agcagccagc
     2401 cgctcaggag ccgttgtacc aacagccgca acccgttgaa cagcagcctg ttgtggagcc
     2461 tgaacccgtt gtagaagaga caaaacccgc gcgtccgccg ctttactact ttgaagaagt
     2521 tgaagagaag cgagcccgtg aacgtgaaca acttgcggcc tggtatcaac cgattccaga
     2581 accggttaaa gaaccagaac cgatcaaatc ttcgctgaaa gcaccttctg ttgcagcagt
     2641 acctccagta gaagccgctg ccgctgtttc cccgctggca tctggcgtga aaaaagcgac
     2701 actggcgacg ggggctgccg caaccgttgc cgcgccagtc ttcagtctgg caaatagcgg
     2761 tggaccgcgt cctcaggtca aagaggggat tggtccgcag ttgccacgac cgaaacgtat
     2821 ccgcgtgcca actcgtcgtg aactggcgtc ttacggtatt aagctgccct cacagcgtgc
     2881 ggcggaagaa aaagcccgtg aagcccagcg caatcagtac gattctggcg atcagtacaa
     2941 cgatgatgaa atcgatgcga tgcagcagga tgaactggca cgtcagttcg cccagacaca
     3001 gcagcaacgc tatggcgaac agtatcaaca tgatgtgccc gtaaacgcag aagatgcaga
     3061 tgctgcggca gaggctgaac tggctcgtca gtttgcgcaa actcaacaac aacgttattc
     3121 cggcgaacaa ccggctgggg cgaatccgtt ctcgctggat gattttgaat tttcgccaat
     3181 gaaagcgttg ctggatgatg gtccacacga accgttgttt acgccaattg ttgaacctgt
     3241 acagcagccg caacaaccgg ttgcaccgca gcagcaatat cagcagccgc aacaaccagt
     3301 tccgccgcag ccgcagtatc agcagccaca acagccggtt gcgccgcagc cacaatatca
     3361 gcagccgcaa caaccggttg cgccacagca gcaatatcag cagccgcaac aaccggttgc
     3421 gccgcagcag cagtatcagc agccacaaca gccagttgcg ccacaaccgc aggataccct
     3481 gcttcatccg ctgttgatgc gtaatggcga cagccgtccg ttgcataaac cgacgacgcc
     3541 gctgccttct ctggatttgc tgacaccgcc gccgagcgaa gtggagccgg tagatacctt
     3601 tgcgcttgaa caaatggctc gcctggtgga agcgcgtctg gctgatttcc gtattaaagc
     3661 cgatgtcgtc aattactctc cggggccggt tatcactcgc tttgaattga acctggcacc
     3721 gggcgtaaaa gcggcgcgca tttctaactt gtcacgggac cttgcccgtt cactttcgac
     3781 ggtggcggtg cgtgtcgttg aagttattcc tggcaaaccc tatgtaggtc tggagttacc
     3841 gaataaaaaa cgacaaaccg tttatctgcg cgaagttttg gataacgcca aattccgcga
     3901 taatccgtcg ccattaaccg tggtgctggg taaagatatc gccggtgagc cggtggttgc
     3961 cgatctggcg aaaatgccgc acttgttggt tgcggggact accggttccg gtaaatctgt
     4021 cggtgtgaac gcgatgatcc tgagcatgct ttataaagca cagccagaag atgtgcgttt
     4081 catcatgatc gacccgaaaa tgctggagct ttcggtttat gaaggcattc cgcatctgtt
     4141 aacggaagtc gttactgata tgaaagatgc cgccaacgcg ctgcgctggt gtgttaacga
     4201 gatggagcgt cggtataaac tgatgtctgc gctgggtgtg cgtaatctgg cgggttataa
     4261 cgaaaaaatt gctgaagccg atcgcatgat gcgtccgatt ccagacccgt actggaagcc
     4321 gggtgacagt atggatgccc agcatccggt gctgaaaaaa gaaccataca ttgtggtgtt
     4381 ggttgacgaa tttgccgacc tgatgatgac ggtaggtaaa aaagtggaag agctgatagc
     4441 acgtctggcg caaaaagccc gtgccgcggg tatccacctc gtactggcaa ctcagcgtcc
     4501 atcggttgat gttattactg gtctgattaa agcgaatatt ccgacccgta tcgcctttac
     4561 cgtatccagt aagattgact cacgtaccat tcttgatcag gctggcgcgg aatcactgct
     4621 gggtatgggg gatatgctct actctgggcc gaactccacg ttgccggtac gtgtccatgg
     4681 tgcttttgtt cgcgatcagg aagttcatgc cgtggtgcag gactggaaag cgcgtggtcg
     4741 cccacagtat gttgatggca tcacctccga cagcgaaagc gaaggtggtg cgggtggttt
     4801 cgatggcgct gaagaactgg atccgttgtt cgatcaggcg gtgcagtttg tcactgaaaa
     4861 acgcaaagcg tcaatttctg gcgtacagcg tcagttccgc attggttata accgtgcagc
     4921 gcgtattatc gaacagatgg aagcgcaggg gattgtcagc gaacaggggc acaacggtaa
     4981 tcgtgaagtg ctggccccac cgccgtttga ctaactaatg catcgtatgc cggataaggc
     5041 gcggtagcgt cgcatccggc actctatcaa ctgaaaattc agtattttct tctttcctca
     5101 agctgattat tagcctggaa tagagagtag agggaactcc cgatcgggag tgacgtaatt
     5161 tgaggaataa tgatgaaaaa aattgccatc acctgtgcat tactctcaag cttagtagca
     5221 agcagcgttt gggctgatgc cgcaagcgat ctgaaaagcc gcctggataa agtcagcagc
     5281 ttccacgcca gcttcacaca aaaagtgact gacggtagcg gcgcggcggt gcaggaaggt
     5341 cagggcgatc tgtgggtgaa acgtccaaac ttattcaact ggcatatgac acaacctgat
     5401 gaaagcattc tggtttctga cggtaaaaca ctgtggttct ataacccgtt cgttgagcaa
     5461 gctacggcaa cctggctgaa agatgccacc ggtaatacgc cgtttatgct gattgcccgc
     5521 aaccagtcca gcgactggca gcagtacaat atcaaacaga atggcgatga ctttgtcctg
     5581 acgccgaaag ccagcaatgg caatctgaag cagttcacca ttaacgtggg acgtgatggc
     5641 acaatccatc agtttagcgc ggtggagcag gacgatcagc gcagcagtta tcaactgaaa
     5701 tcccagcaaa atggggctgt ggatgcagcg aaatttacct tcaccccgcc gcaaggcgtc
     5761 acggtagatg atcaacgtaa gtagaggcac ctgagtgagc aatctgtcgc tcgatttttc
     5821 ggataatact tttcaacctc tggccgcgcg tatgcggcca gaaaatttag cacagtatat
     5881 cggccagcaa catttgctgg ctgcggggaa gccgttgccg cgcgctatcg aagccgggca
     5941 tttacattct atgatcctct gggggccgcc gggtaccggc aaaacaactc tcgctgaagt
     6001 gattgcccgc tatgcgaacg ctgatgtgga acgtatttct gccgtcacct ctggcgtgaa
     6061 agagattcgc gaggcgatcg agcgcgcccg gcaaaaccgc aatgcaggtc gccgcactat
     6121 tctttttgtt gacgaagttc accgtttcaa caaaagccag caggatgcat ttctgccaca
     6181 tattgaagac ggcaccatca cttttattgg cgcaaccact gaaaacccgt cgtttgagct
     6241 taattcggca ctgctttccc gtgcccgtgt ctatctgttg aaatccctga gtacagagga
     6301 tattgagcaa gtactaactc aggcgatgga agacaaaacc cgtggctatg gtggtcagga
     6361 tattgttctg ccagatgaaa cacgacgcgc cattgctgaa ctggtgaatg gcgacgcgcg
     6421 ccgggcgtta aatacgctgg aaatgatggc ggatatggcc gaagtcgatg atagcggtaa
     6481 gcgggtcctg aagcctgaat tactgaccga aatcgccggt gaacgtagcg cccgctttga
     6541 taacaaaggc gatcgctttt acgatctgat ttccgcactg cataagtcgg tacgtggtag
     6601 cgcacccgat gcggcgctgt actggtatgc gcgaattatt accgctggtg gcgatccgtt
     6661 atatgtcgcg cgtcgctgtc tggcgattgc gtctgaagac gtcggtaatg ccgatccacg
     6721 ggcgatgcag gtggcaattg cggcctggga ttgctttact cgcgttggcc cggcggaagg
     6781 tgaacgcgcc attgctcagg cgattgttta cctggcctgc gcgccaaaaa gcaacgctgt
     6841 ctacactgcg tttaaagccg cgctggccga tgctcgcgaa cgcccggatt atgacgtgcc
     6901 ggttcatttg cgtaatgcgc cgacgaaatt aatgaaggaa atgggctacg ggcaggaata
     6961 tcgttacgct catgatgaag caaacgctta tgctgccggt gaggtttact tcccgccgga
     7021 aatagcacaa acacgctatt atttcccgac aaacaggggc cttgaaggca agattggcga
     7081 aaagctcgcc tggctggctg aacaggatca aaatagcccc ataaaacgct accgttaatg
     7141 ttatcgttgc ggtaatgttg ttactgtatc cctgtggtcg caggctgtgg ccacatctcc
     7201 catttaattc gataagcaca ggataagcat gctcgatccc aatctgctgc gtaatgagcc
     7261 agacgcagtc gctgaaaaac tggcacgccg gggctttaag ctggatgtag ataagctggg
     7321 cgctcttgaa gagcgtcgta aagtattgca ggtcaaaacg gaaaacctgc aagcggagcg
     7381 taactcccga tcgaaatcca ttggccaggc gaaagcgcgc ggggaagata tcgagccttt
     7441 acgtctggaa gtgaacaaac tgggcgaaga gctggatgca gcaaaagccg agctggatgc
     7501 tttacaggct gaaattcgcg atatcgcgct gaccatccct aacctgcctg cagatgaagt
     7561 gccggtaggt aaagacgaaa atgacaacgt tgaagtcagc cgctggggta ccccgcgtga
     7621 gtttgacttt gaagttcgtg accacgtgac gctgggtgaa atgcactctg gcctcgactt
     7681 tgcagctgca gttaagctga ctggttcccg ctttgtggta atgaaagggc agattgctcg
     7741 catgcaccgc gcactgtcgc agtttatgct ggatctgcat accgaacagc atggctacag
     7801 tgagaactat gttccgtacc tggttaacca ggacacgctg tacggtacgg gtcaactgcc
     7861 gaaatttgct ggcgatctgt tccatactcg tccgctggaa gaagaagcag acaccagtaa
     7921 ctatgcgctg atcccaacgg cagaagttcc gctgactaac ctggtgcgcg gtgaaatcat
     7981 cgatgaagat gatctgccaa ttaagatgac cgcccacacc ccatgcttcc gttctgaagc
     8041 cggttcatat ggtcgtgaca cccgtggtct gatccgtatg caccagttcg acaaagttga
     8101 aatggtgcag atcgtgcgcc cagaagactc aatggcggcg ctggaagaga tgactggtca
     8161 tgcagaaaaa gtcctgcagt tgctgggcct gccgtaccgt aaaatcatcc tttgcactgg
     8221 cgacatgggc tttggcgctt gcaaaactta cgacctggaa gtatggatcc cggcacagaa
     8281 cacctaccgt gagatctctt cctgctccaa cgtttgggat ttccaggcac gtcgtatgca
     8341 ggcacgttgc cgcagcaagt cggacaagaa aacccgtctg gttcataccc tgaacggttc
     8401 tggtctggct gttggtcgta cgctggttgc agtaatggaa aactatcagc aggctgatgg
     8461 tcgtattgaa gtaccagaag ttctgcgtcc gtatatgaac ggactggaat atattggcta
     8521 atacccaatt tttctgaatc taaaaagcgc ctgcgggcgc tttttttgtc tccctttgat
     8581 accgaacaat aattactcct cacttacacg taatactact ttcgagtgaa aatctaccta
     8641 tctctttgat tttcaaatta ttcgatgtat acaagcctat atagcgaact gctatagaaa
     8701 taattacaca atacggtttg ttactggaat caatcgtgag caagcttgag tgagccatta
     8761 tgaaaacgaa aatccctgat gcggtattgg ctgctgaggt gagtcgccgt ggtttggtaa
     8821 aaacgacagc gatcggcggc ctggcaatgg ccagcagcgc attaacatta ccttttagtc
     8881 ggattgcgca cgctgtcgat agcgccattc caacaaaatc agacgaaaag gttatctgga
     8941 gcgcctgtac agttaactgt ggtagtcgct gcccgctacg tatgcacgtc gtggacggtg
     9001 aaatcaaata tgtcgaaacg gacaataccg gcgatgacaa ttacgacggc ctgcaccagg
     9061 ttcgcgcctg cctgcgtggg cgttccatgc gtcgccgtgt ctacaatccg gaccgcctga
     9121 aatatccgat gaaacgagtc ggggcgcgcg gtgaaggcaa attcgagcgc attagctggg
     9181 aagaagccta cgacatcatc gcgaccaata tgcagcgcct gatcaaagag tacggcaacg
     9241 agtctatcta tctgaactat ggcaccggta cgctgggcgg caccatgacc cgctcctggc
     9301 cgccgggaaa taccctggtc gcgcggctga tgaactgctg cggcggctat ctgaaccatt
     9361 acggcgacta ctcctccgcg caaattgcgg aaggtttgaa ctatacctac ggcggctggg
     9421 cagatggcaa cagcccgtcg gatatcgaaa acagtaagct ggtagtgctg tttggtaata
     9481 accctggcga aacgcgaatg agtggcggtg gggtgactta ctatcttgaa caggcacgcc
     9541 agaaatctaa tgcccgcatg atcatcatcg atccgcgcta taccgacacc ggtgccgggc
     9601 gcgaagatga gtggatccct attcgtccgg gaacagatgc cgcactggtt aacggtctgg
     9661 cgtacgtcat gatcactgaa aacctggtgg atcaggcatt cctcgataaa tattgcgttg
     9721 gctacgatga gaaaaccctg ccagccagtg cgccgaaaaa tggccactat aaagcttata
     9781 ttctgggtga agggccagat ggcgtggcta aaacgccgga atgggcctcg caaatcactg
     9841 gtgttccggc agacaaaatc atcaaattgg ctcgtgaaat cggtagtacc aaaccggcgt
     9901 ttatcagcca gggatggggc ccgcagcgtc acgctaacgg tgaaatcgca acccgtgcta
     9961 tctcgatgct ggcgattctg accggtaacg ttggtattaa cggaggcaac agcggcgcgc
    10021 gtgaaggttc atacagctta ccgtttgtcc gtatgccgac cttggaaaac ccgatccaga
    10081 ccagcatttc gatgtttatg tggaccgatg ccattgaacg tggcccggaa atgacggcgc
    10141 tgcgtgatgg tgtacgcggg aaagataagc tggatgtgcc gatcaaaatg atctggaact
    10201 atgccggtaa ctgcctgatt aaccagcatt ctgaaatcaa ccgtacccat gaaatccttc
    10261 aggatgataa gaagtgcgag ctgattgtgg ttatcgactg ccacatgacc tcatcggcga
    10321 aatatgctga catcctgctg cctgactgca ccgcttccga acagatggac tttgcgctgg
    10381 atgcatcctg cgggaatatg tcttacgtga ttttcaacga tcaggtgatt aaaccgcgct
    10441 ttgaatgtaa gaccatctat gaaatgacca gcgaactggc aaaacgtctt ggcgttgagc
    10501 aacagtttac tgaaggccgt acccaggaag agtggatgcg gcatctgtat gcccagtcgc
    10561 gggaagcgat tcctgaactg ccaacgtttg aagagttccg caagcagggg atctttaaaa
    10621 agcgcgaccc acaagggcat cacgttgctt ataaagcctt ccgtgaagat ccgcaggcaa
    10681 acccactgac tacgccatcg ggcaaaattg agatttattc gcaggcgctg gctgacattg
    10741 ccgctacctg ggaattgcct gaaggcgatg tgatcgatcc actgccgatc tacacgccgg
    10801 gctttgaaag ttatcaggat ccgctgaaca aacagtatcc gctgcagctt acaggtttcc
    10861 actataaatc tcgcgttcac tcaacttacg gcaacgttga tgtgctgaaa gcggcttgcc
    10921 gtcaggaaat gtggatcaac ccgcttgatg cccaaaaacg cggtatccac aacggcgata
    10981 aagtcaggat ctttaacgat cgtggtgagg ttcatattga ggcgaaagtg acgccacgaa
    11041 tgatgccggg tgtggtcgca ctgggtgaag gtgcctggta tgacccggat gcaaaacgtg
    11101 tcgataaggg tggttgtatt aacgtactga ccactcaacg tccgtctcct ctcgctaagg
    11161 ggaatccgtc acatacaaac cttgttcagg ttgaaaaggt gtaaggagta accgatgaca
    11221 acccagtatg gattttttat tgattccagc cgttgcaccg gttgcaaaac ctgcgagctg
    11281 gcctgtaaag actacaaaga tttgacgcca gaagtcagct tccgccgcat ttatgaatat
    11341 gctggcggcg actggcagga agataacggt gtctggcacc agaacgtgtt tgcctactat
    11401 ctgtcgattt catgtaacca ctgcgaagat ccggcttgta ctaaagtctg cccgagcggt
    11461 gcgatgcata aacgtgaaga tggttttgtt gtggtcgatg aagatgtgtg cattggctgc
    11521 cgctactgcc atatggcttg cccgtatggc gcaccgcaat ataacgaaac gaaaggccat
    11581 atgaccaaat gcgatggttg ttatgaccgt gttgcggagg gtaaaaagcc gatctgtgtt
    11641 gaatcttgtc cgctgcgggc gctggatttc ggccctatcg acgagctgcg taaaaaacat
    11701 ggcgatctgg cggccgttgc gccgttgccg cgagctcact ttaccaaacc gaatattgtg
    11761 atcaaaccca atgccaatag ccgcccgacc ggggatacca ctggctatct ggcaaacccg
    11821 aaggaggtgt gagatgggaa gtggatggca tgaatggccg ctgatgatct tcacggtctt
    11881 cgggcaatgt gtagcaggtg gttttatcgt tctggctttg gcgctgctca aaggcgacct
    11941 gcgagcagaa gcccagcagc gtgttatcgc ctgcatgttt ggtttatggg tgctgatggg
    12001 cattggcttt atcgcctcta tgctccatct tggttcacca atgcgcgctt ttaactcgct
    12061 caaccgggta ggggcttcag cactcagtaa cgaaatcgcc agcggttcga tcttttttgc
    12121 cgtaggcggc atcggctggt tgctggcaat gctgaaaaag ctgtcaccgg cattgcgtac
    12181 gctgtggctg atagtgacga tggttcttgg cgtcatcttt gtctggatga tggtgcgtgt
    12241 gtataacagc attgataccg ttccgacctg gtacagcatc tggacgccga tgggcttctt
    12301 cctgacgatg tttatgggcg gcccgttact gggttacctg ttgttgagtc tggctggcgt
    12361 cgatggctgg gcgatgcgtc tgctgccagc aatttctgta ctggcactgg tagtgagtgg
    12421 cgtggtgtca gtgatgcagg gcgcagagct ggcgactatt catagttctg tgcagcaggc
    12481 cgcagcgctg gtgccggact atggtgcgct gatgtcctgg cggatcgtgc ttttggccgt
    12541 tgccctgtgc ttgtggattg caccacagct aaaaggttat cagcctgcgg ttccgctact
    12601 ttctgtatca ttcattctgc ttctggcagg ggaattaatc ggtcgcggcg tattctatgg
    12661 tttgcatatg accgtgggga tggccgtcgc aagctaatca taacaaccgg ggtttcggcc
    12721 ccggttctct tttatttctg cttcgttaac gtgtcataac tggtcatcaa attacgataa
    12781 tcaggaatgt ggttagagaa caacgtcgcc agtccttcaa tatcattacg ccagtcgcga
    12841 tgcagctcgc acgccacgcc gaaccatgtc atcaattgcg caccagcttg cgacaagcga
    12901 tcccatgccg aatgccgggt aatttcatta aaggtccctg acgcgtcagt cacgacaaag
    12961 acgtcaaacc cttcttcaat ggctgaaagc gccgggaatg ccacgcaaac ttcggttacc
    13021 acaccggcaa taattaactg ttttttacct gtcgctttga cagcttttac aaaatcttcg
    13081 ttatcccagg cgttaatatt tcccgggcga gcaatgtaag gtgtatcggg gaattgtgct
    13141 ttcagttctg gaactaatgg gccgttagga ccggtttcaa aactggtggt aagaatagtt
    13201 ggtaagttga aatacttagc caggtcaccc agcgccagca cgttattttt aaacttatcg
    13261 ggttcgatat cccgtacaag ggaaagtaaa ccagcctggt gatcaacaag caaaacggca
    13321 gcatcatttt tatcaagacg aacatacggt ttggtcatcc tcttctcctt tcgagagtca
    13381 gtggtacgtc tgaaatcgat cagacgcgat gcattgctct gaaagcatag acgggaaata
    13441 tgagtttgct gtgaccatga aatttttcga ctgaacgaag cgtatgaaat ttgtgttagt
    13501 tcaataaaaa caatcagatg agactaatca tctcttcagc attagcgtta tgaatgagta
    13561 atataaatcg ataataccgc cgctgggata tcgcgtattt tcacccattg acaatgtttt
    13621 tggcggtggc atgatgcgca tgaaatttga acttcctcac ggttttaatt catgtccacg
    13681 tatacccagc ctgtcatgct tttgctgtct ggcctgcttt tgttgactct ggcgattgcg
    13741 gtgttaaata cactcgtgcc gctttggctc gcccaggaac acatgtccac atggcaggta
    13801 ggcgttgtca gctcatccta ttttaccggc aaccttgtcg gtacattgct gacagggtat
    13861 gtcattaagc gcattggctt taaccgcagc tattatctgg cctccttcat ttttgccgct
    13921 ggctgtgccg gccttggcct gatgattgga ttctggagct ggttggcttg gcgttttgtc
    13981 gcgggcgtcg gctgtgccat gatttgggtg gttgttgaga gcgcgctgat gtgcagtggg
    14041 acgtcacgta accgtgggcg tttgcttgct gcgtatatga tggtttatta cgtgggaacg
    14101 tttttaggcc agttactggt cagcaaagtt tcaaccgagc tgatgtccgt attgccgtgg
    14161 gttacaggtt tgacgttggc agggatctta ccgctgttgt ttacgcgtgt gctgaatcag
    14221 caggctgaaa accatgattc gacgtcaatt acgtcaatgc taaaactccg tcaggcgcgg
    14281 cttggcgtga atggctgcat tatctcagga atcgttctgg gatctctata tggcctgatg
    14341 ccgctgtacc tcaatcacaa aggggtgagc aatgccagca ttggtttctg gatggcggta
    14401 ctggtcagtg cgggtatcct tggacaatgg ccgattggac gtctggcgga taagtttggt
    14461 cgactgctgg tgttgcgtgt tcaggtcttt gtcgtcattc tcggcagtat cgcgatgctt
    14521 agccaggcgg cgatggcccc agcgttattc atcctcggtg ccgctggctt tacgctatat
    14581 ccggtggcga tggcatgggc ttgcgagaaa gttgaacatc atcaactggt ggcgatgaac
    14641 caggccttac tgttgagcta tactgtggga agtctgcttg gcccgtcatt taccgctatg
    14701 ctaatgcaga atttctccga taatttattg tttatcatga tcgccagcgt atcgtttatc
    14761 tatttgctga tgctgctgcg caacgccggt catacgccga aacccgttgc tcacgtgtaa
    14821 atgaattcaa gcagagtgtg aacttactgt ttcacactct gcttttttgt ttcttctatc
    14881 tgacttgctt tattccaaat tttattcgtt taaaaataaa atgtgcagca ggttataatt
    14941 ttgcatttcg ctatttccgc acttcttatt tgccgcgcat aatccctcgt tttacagatg
    15001 cccctttaat tttggcgaag gatttgtcta tggctgggaa tgttcaggaa aaacagttgc
    15061 gatggtacaa cattgcgctg atgtctttta tcactgtctg gggttttggc aacgttgtta
    15121 ataactatgc caaccagggg ctggtggttg ttttttcatg ggtgtttatc tttgcactct
    15181 atttcacacc ttatgcgcta attgttggtc agttaggctc gaccttcaaa gatgggaagg
    15241 gcggggtcag tacctggatt aaacacacga tgggacccgg actggcttat ctcgccgcgt
    15301 ggacctactg ggtggtgcat attccctatc tggcacaaaa accccaggca attctgattg
    15361 cgctcggttg ggcgatgaaa ggcgacggtt cgctaatcaa agaatattca gtcgtagcgt
    15421 tacaggggtt aacgctggtg ctgtttatct tctttatgtg ggttgcttca cgcggtatga
    15481 aatcgctgaa aatcgtcggt tctgtggcag ggattgctat gtttgttatg tcgctcctgt
    15541 atgtggcgat ggcggtaacc gcgcctgcaa ttactgaagt gcatattgcg accacaaaca
    15601 ttacctggga aacgttcatt cctcatatcg actttaccta cattaccact atttcaatgc
    15661 tggttttcgc ggttggcgga gcagagaaga tttctcctta cgttaatcaa acgcgcaacc
    15721 caggaaaaga atttccaaaa gggatgttat gcctggcggt gatggttgcg gtttgtgcca
    15781 ttctgggctc gctggcgatg gggatgatgt ttgattcgcg taatatcccg gatgacttaa
    15841 tgaccaacgg tcagtattac gcctttcaga agctgggcga gtattacaac atgggtaata
    15901 ctttaatggt gatttacgcc attgcgaata ccctgggaca agtagcggcg ctggtattct
    15961 cgattgatgc cccgcttaaa gtgctattag gtgatgctga cagcaaatat attccagcca
    16021 gtttatgtcg taccaacgct tctggtacgc ccgttaatgg ctattttctg accctggtac
    16081 tggtggcgat tctgattatg ctgccgactc tcggcattgg tgatatgaac aatctctata
    16141 aatggctgtt gaaccttaat tcggtagtga tgccgctgcg ttatttatgg gtatttgttg
    16201 catttattgc agtcgttcgc ttggcgcaga aatataaacc agaatatgtc tttattcgta
    16261 ataagcctct ggcaatgacc gtcgggattt ggtgttttgc ctttaccgcc tttgcctgtt
    16321 tgacggggat cttcccgaaa atggaagcct tcactgcaga gtggaccttc cagttggcgc
    16381 tgaatgttgc aacgccgttt gtgctggtag gattaggact gatattcccg ctgctggcgc
    16441 gtaaagcgaa tagtaaataa ttattgtggt cggtgacgct gactctggca gatctgaccc
    16501 gtttttacat aatcgagaaa tgcgcgcaag ccgcaggaca tatactggcg gtttggataa
    16561 tagatctgga agcctggacg ctctgtgctc cagtcttcca gtacacattc taaacgacca
    16621 gtatcaaggt actccttgat ctgttcatag agcagatacc cgataccagc acccatcaaa
    16681 acggcctcca gttcagcatc aacatcatcc agaatgatat ttcctgcgac agcaatttcc
    16741 agctcctttg caaattgcca gtggaaaggt ttgccgctgg gataacgaaa aacaacacat
    16801 tgatgattaa gcagatcatg aggatggcgg ggtttgccat atcttgcaaa gtactctggc
    16861 gttgctgcta cacataattt cactggcggg ccgatcgcca cgctgatcat atctttttcg
    16921 acgatgcaac taagtcgaac gccagcgtca aagccctgtt ggacgatatc gacaagagag
    16981 tcgtcagttg tgagctcgac tttaatatca ggatattcac gtgtgaaacc aaccagtaaa
    17041 gacattaaaa atatacgtgc agctacccgg gcggcattga ttttgagcgt tcctgtcggt
    17101 gtcagacgaa aatcattcat ctcatctaac atgatctgaa tttcgtcgaa agctgggcgc
    17161 aatcgttcat agagattaga acccgcttcc gttaacgata cgcttcgggt tgtccgattg
    17221 aataagcgaa ttttaagacg ttgttccagt gttttaatac tatggctaat ggcggacgag
    17281 gataagccta actcatcgcc cgctgcacga aagctttgat tacgggccac ggcaaagaaa
    17341 gtggcaaagt cagacatatt catccgcatt agtgaaaatc cttcattaac tcatcctgaa
    17401 tcatcacgtt tacaggatta tgccgcctgc gtaaagtgcg ctccagaact taacgtggag
    17461 gtaaaattat gcagtctgaa cgtatttatt tggtatgggc ccatcctcgt catgattcat
    17521 tgaccgcaca tattgctgat gcgatccatc agcgggcaat ggagcggaaa atacaggtga
    17581 cggaactcga tttatatcgg cgtaatttca acccagtgat gacgccggaa gatgaaccag
    17641 actggaagaa tatggataaa cgttattctc cagaggttca tcagctttat tcagagctgc
    17701 ttgaacatga cacgttagtg gtggtttttc ctctctggtg gtacagcttc ccggcaatgc
    17761 taaaaggata tattgacaga gtatggaata atgggctggc ttatggagat gggcacaaat
    17821 taccattcaa taaagttcgt tgggtggcgc tggttggagg agacaaagaa tcatttgtcc
    17881 agatgggctg ggaaaaaaat ataagcgatt atttaaaaaa tatgtgcagt tatcttggta
    17941 ttgaagatgc cgatgtcact ttcttgtgta atacagtggt attcgatggg gaagaacttc
    18001 acgcgagcta ttatcagtcg ttattatctc aggtacggga tatggtagat gcactataag
    18061 atgtgttaaa aacgctgtag cagaatgaag cgcggaataa aaaagcggca actcaataaa
    18121 gttgccgctt tacggggaaa ttagaacatt accttatgac cgtactgctc aagaatgcct
    18181 ttcacgcgtt ccatggtctc tttcttcggt ggtttaacac cgtcgagttt gtactcttca
    18241 cccattgcca cccatttgtg tttgcccagc tcgtggtagg ggagaagctc gattttctca
    18301 acgttgccca tatcacgggt aaattcaccg aggcgatgcg ctgaatcgtc atcgtcagac
    18361 cagcctggga caacaacgta gcggatccac accttcacat ttttgttcgc cagatattta
    18421 gcgaactcca gcgtgcggtg gttggaaact ccaaccagat tttggtggat ctcgtcgttc
    18481 atctgtttga gatcgagcat taccaggtcg gttacttcca gcagttcatc aatcaccgga
    18541 tcgtaacgac gaacaaaacc gttggtgtcc agacaggtat gaatgccttc ttttttgcag
    18601 gcgcggaacc agtcacgaac aaactcagct tgcaggattg cttcaccgcc ggatgcggta
    18661 acgccgccgc cggaagcgtt cataaagtgg cgataggtca ccacttcctt catcaaatct
    18721 tcaacggtaa cttctttacc gccatgcgtg tcccaggtgt cgcggttatg acaatacagg
    18781 cagcgcatca ggcagccctg gaaaaaggtg ataaagcgaa tacctgggcc gtctacggtt
    18841 ccacaggatt caaaggagtg aatgcgacca ataactgaca ttgcggtgtt tctccagatg
    18901 tggcccatct gaggccgtgt tggtgcgcag ctcgaaggct acgtcgagtc tgttttggca
    18961 gtcaccttaa agtatagata gctgacaaaa aaggctctcg cgctaaaaaa ggccccactt
    19021 tcgtggagcc tttattgtac gctttttact gtacgatttc agtcaaatct aattacatag
    19081 attgagtgaa ggtacgagta ataacgtcct gctgctgttc tttagtcagc gagttgaaac
    19141 gtactgcgta gccagataca cggatggtca gctgcggata tttttccggg ttttccatcg
    19201 cgtcgagcag catttcacgg ttcatcacgt taacgttcag gtgctgacca ccttcgatgg
    19261 atgcttcgtg gtggaagtaa ccatccatca gaccagccag gttggtctta cgaacttcgt
    19321 cgtctttacc cagtgcgttc ggaacgatag agaaggtgta ggagatacca tctttagcgt
    19381 aagcaaacgg cagtttagca acggaagtca gagaggctac tgcacctttc tggtcacgac
    19441 cgtgcatcgg gttagcaccc ggtccgaacg gcgcgccagc acgacgaccg tctggggtgt
    19501 tacccgtttt cttaccatac acaacgttag aagtgatggt cagaacagac tgagtcggga
    19561 tagcgtcacg gtaggtgtgc agtttctgaa ttttcttcat gaaacgttct accaggtcaa
    19621 cagccaggtc atctacacgc ggatcattgt taccaaactg cgggtattcg ccttcgattt
    19681 cgaagtcgat agccagaccg tcttcgtcac gaatcggttt aactttcgca tatttgattg
    19741 cagacaggga gtcagcagca acggacagac cagcgatacc acacgccatg gtgcggataa
    19801 cgtcacggtc gtgcagcgcc atcagagagg cttcgtagct gtacttgtcg tgcatgtagt
    19861 ggatgatgtt cagtgcagtg atgtactgtt tagccagcca gtccatgaag tgatccatgc
    19921 gctccatcac ttcatcatag ttcaggacat cgcctttgat cggttcagac ttcggaccaa
    19981 cctgcatttt cagtttttcg tcaacgccgc cgttgattgc gtacagcatg gttttcgcca
    20041 ggtttgcacg cgcaccgaag aactgcattt gtttaccaac gatcatcggg cttacgcagc
    20101 aagcaatagc gtagtcatcg ttgttgaagt ccggacgcat caggtcatcg ttctcatact
    20161 gcagagaaga ggtgtcgatg gacactttag cggcgaattt cttgaagttc agcggcagtt
    20221 tttcagacca cagaatggtc atgttcggtt ccggagacgg acccatggtg tacagggtgt
    20281 tcaggaaacg gaagctgttt ttggtaacca gggtacgacc gtcgaggccc ataccaccga
    20341 tagattcggt tgcccagatc gggtcgccag agaacagttc atcgtattcc ggagtacgca
    20401 ggaagcgaac catacgcagt ttcatgacca ggtggtcaac catttcctgc gcttcttgtt
    20461 cggtgatctt gccagctttc aggtcacgtt cgatgtacac atccaggaag gtggaggtac
    20521 gaccgaagga cattgcagca ccgttctgag acttaacagc agccaggtag ccgaagtaag
    20581 tccactggat agcttcctga gcgttggtag ccggaccaga gatgtcgtag ccgtatttcg
    20641 cagccatttc tttcatctga cccagagcgc ggtgctgttc agcgatttct tcgcgcagac
    20701 ggatagtctg ttccaggttt acgccgtttt ccagatcagc ctgcagagaa gtgaactgtg
    20761 ccagtttgtc tttcatcagg tagtcgatac cgtacagcgc aacgcgacgg tagtcaccga
    20821 tgatacggcc acggccatat gcatctggca gaccggtcag aacaccagat ttacggcaac
    20881 gcaggatgtc cggagtgtaa acgtcgaaca cgccctggtt gtgagtttta cggtattcag
    20941 tgaagatttt tttgatcatc ggatccagtt cgcggttgta cgctttgcag gaaccttcga
    21001 tcattttgat accaccgaac gggataagag cacgtttcag cggagcttca gtctgcagac
    21061 caacgatttt ctcaagctgc ttgttgatgt agccagcgtc gtgagaggtg atggtggaag
    21121 caacagcggt gtcaaagtca actggcgcgt gagtgcggtt ttccagttta acgccttcca
    21181 ttactttgtc ccacagggtg gtggtcgctt cagtagcgcc agccaggaag gactcgtcac
    21241 cctcgtacgg agtgtagttt ttctgaatga agtcacggac gtttacttca ttctgccagt
    21301 cacctttggt aaaaccttcc caggctgtgg ctaacttttc attaagctcg gacatgtaac
    21361 acctaccttc ttaagtggat tttttattta ctgcgtactt cgacaaccat taatggtggt
    21421 cgttttcacg caggtaaatg acccagtatg tcaacccaac caacaaacca ccaccgataa
    21481 tgttgccgat cgtaaccgga atcaggttat cagtgatgaa attcatcacg gtcaggtgag
    21541 aaaaattttc cggtgcagaa ccgactgcgg tccaaaattc cggggatgcg aagtcgcgga
    21601 ttacaatacc catcgggatc ataaacatgt ttgcgatact gtgctcaaaa ccgctggcaa
    21661 caaacatcgc gaccggcagc accataatga acgctttgtc catcaggctg cggccagaat
    21721 aactcatcca tactgccaga cataccatca ggtttgccag gataccaaga cagacggcct
    21781 caataaaagt atggtgcact ttgtggtcgg cggtttgtag gacgtttagt ccccattgac
    21841 catttgcggt catatactcg ccggaaagcc acattaaaag tacaaacagc agtgcgccga
    21901 ccaggttgcc aaaatagaca tttagccagt ttttcgccaa ctgaccccag gtgatgcgcc
    21961 cactcgcctt agcaacaaca atcaacacgg tggaagtaaa gagatcggct ccgcagacaa
    22021 cacaaagaat cagccccaga gagaagcaaa tgccgccaac cagttttgcc atgccgaagg
    22081 gcattgtgcc tgtgccagtg gttgctgtga tatagaagac gaatgcgatt gagatgaaaa
    22141 caccggcggt aatcgccaga tagaaagtct taagcggatg tttcgttgct ttatagacac
    22201 ccgcctcttc ggccactttg gccattgcag caggaagtaa aagatcaaaa gggttgtcag
    22261 ctttcacact aactctctct ttattaagtc ggcgacgaga tactaacaaa gcattataga
    22321 tgagaaattg atatagatca tatctcgcct ggcttatagg cccgtaactc gcatggtttt
    22381 tatgcaaata cggagtaaat atttgattat ccaaataaaa ataaatttta aaaattaaca
    22441 aatgagttga attttttccg catcctccgc taaaacagtt aattaaaagg gagcatcagg
    22501 cgaataaagt aacaatatcg atcgtattta ttaaatacaa attaccgata tttaacctta
    22561 taattacaat tattttatta atgcaaatat atgtaaagcg gggcattaaa aaaacgcccc
    22621 gtaatataac tcagactaat cattaagcct acattgcgta ggctatttga ttttattttg
    22681 cccagaatgc tgctttggcg cgctgcagct tttcgtaggc cttcaacaac gactgatgtg
    22741 cagcaaacgc gtgcagatcg ctatctaccg gttgcaggcc gtaaaacgcc gcttcgccgc
    22801 tcattgccgc actggcggct tctacggcat ctgcgccgta catgcgaaca aacgcattca
    22861 gatattgcag cggctggcga tcttcttcct gtgccagtaa taacaacgtt tgcaggcagc
    22921 gataatagtt ggcgcgttcc ggactaaata ctgatgagtt aaactccatc gtccattcgg
    22981 tccagaccag agcctgttcc agatcgccac cagccagcgc cagcatggct tttaattcac
    23041 cgatacgcag ggtgtaccaa ccgttatccg acccggtcgc cagacccaac agctcacgca
    23101 cgcgggtaaa gtcatcaaaa ccttcttcat ccagttgctc gatgaggttc aggtaatctt
    23161 ctttttccca ctcgctgcct ggtagcgaaa gaatcgtttc acgtaaatgg ctgcccatac
    23221 tgttattcgc gagccacaga tcttcagccg gataaatatc ggacatgcca ggcacgataa
    23281 tacggcaagc ataaacgccc agatgctcgt aatcggcaat ataaacttct ttatcttctt
    23341 tgttgaagat agccatcagt gtggcgaact cttcttccgt ggtgccggag aaattccagt
    23401 ccacaaacgg ataatcggca tcctgcttga acaggtccca ggagattaaa ccgctggaat
    23461 cgataaagtg cgtttcgagg ttggtatgtt cagcgacttc ttcatcatcg aaggttggcg
    23521 gagtaaacac atccaaatct ttcaggccac gaccttgcag cagctcggtc acggtacgtt
    23581 ccagtgctac gccaaaatca ggatgcgcac cgaaagaggc aaagcaggta ccgttagcag
    23641 gattgaacag taccacgcaa atcaccggat actggccgcc aagcgaaccg tcataagcga
    23701 agattgggaa accctccgct tccagcgttt cgatggcttc aactactgct gggtaacgcg
    23761 ccagcacgtc tgccgggatc tctggcaggc tgatgctttc agcaataatg cggtttttca
    23821 cgtagcgttc gaaaacttca gacaatccct gaacgcgtgc ttcgttgcgg gtattacctg
    23881 cggacatacc gttggagacg tacaggttac caatgatatt catcggaata taaacggtct
    23941 gattgtcgga ctgacgcgta aacggcaggc cgcaaatacc acgatcttcg ttaccggatt
    24001 gtaggtcaat cagcatgctg ccggtcagtt cattctccgg atcataaaac gcgcgcagac
    24061 ggtcatcgag cagcccttct ggcacatcgt cattttcggt cagtgggaac catttttcgt
    24121 tgggataatg cacgaacgga ccgttggcga tggtttcgcc cagccagaag tccgcaaaaa
    24181 agtagttggt tgagagacgc tcgaaatatt caccgagtgc agaagccagc gccgctttct
    24241 tggttgcgcc tttaccgttg gtaaaacaca gtgcgcactc tttgtcgcga atatgtacag
    24301 accagacgtt aggcacggga ttcagccagg aggcctcttc aatctgaaag ccgaggtctg
    24361 aaagtttttg ctggaagcga gcgatggaat cttccagagc ggcatctttg ccggggataa
    24421 atgtttgcgt catgaaaatc actttagtcg tacggaaagc gcgcaataat acgggtttta
    24481 tctcaaaggt gctatcaccg ccgccatgcc gatgaactgt tgactatgct tttagcggat
    24541 aaaccacgtt aagagcataa aaatgaaggc gttcgatctc caccgtatgg catttgataa
    24601 agtgcctttt gatttccttg gcgaagttgc actacgtagt ctttatacct ttgtactggt
    24661 ctttttgttc ctcaaaatga ccggaagacg cggtgtgcgg cagatgtcgc tgtttgaagt
    24721 tttaatcatt ctgacgctgg gatcagcggc gggagatgtg gcgttttatg atgatgtgcc
    24781 gatggtcccg gtacttatcg tctttattac tctggcgttg ttataccgcc tggtaatgtg
    24841 gttgatggcg cacagtgaaa aactggaaga tcttctggaa ggcaagccag ttgtcattat
    24901 tgaagatggc gagctggcct ggtcgaaact caataactcc aacatgacgg aatttgagtt
    24961 ctttatggag ctacgattgc gtggcgtgga gcagctgggg caggtacgtc tggcgattct
    25021 cgaaaccaac gggcaaatca gtgtctattt ctttgaagat gacaaggtga aaccgggttt
    25081 acttatttta cccagtgatt gtacgcagcg ttacaaagtg gtgccggagt cggcggacta
    25141 tgcctgtatt cgttgtagtg aaatcattca tatgaaagcg ggggaaaaac aattatgtcc
    25201 gcgctgtgca aatccagaat ggacgaaggc aagtcgggca aaacgggtga cctgacagta
    25261 aaaacatcgg ctttttgcta ataatccgag agattctttt gtgtgatgca agccacattt
    25321 ttgccctcaa cggttttact cattgcgatg tgtgtcactg aatgataaaa ccgatagcca
    25381 caggaataat gtattacctg tggtcgcaat cgattgaccg cgggttaata gcaacgcaac
    25441 gtggtgaggg gaaatggctc aaatcttcaa ttttagttct ggtccggcaa tgctaccggc
    25501 agaggtgctt aaacaggctc aacaggaact gcgcgactgg aacggtcttg gtacgtcggt
    25561 gatggaagtg agtcaccgtg gcaaagagtt cattcaggtt gcagaggaag ccgagaagga
    25621 ttttcgcgat cttcttaatg tcccctccaa ctacaaggta ttattctgcc atggcggtgg
    25681 tcgcggtcag tttgctgcgg taccgctgaa tattctcggt gataaaacca ccgcagatta
    25741 tgttgatgcc ggttactggg cggcaagtgc cattaaagaa gcgaaaaaat actgcacgcc
    25801 taatgtcttt gacgccaaag tgactgttga tggtctgcgc gcggttaagc caatgcgtga
    25861 atggcaactc tctgataatg ctgcttatat gcattattgc ccgaatgaaa ccatcgatgg
    25921 tatcgccatc gacgaaacgc cagacttcgg cgcagatgtg gtggtcgccg ctgacttctc
    25981 ttcaaccatt ctttcccgtc cgattgacgt cagccgttat ggtgtaattt acgctggcgc
    26041 gcagaaaaat atcggcccgg ctggcctgac aatcgtcatc gttcgtgaag atttgctggg
    26101 caaagcgaat atcgcgtgtc cgtcgattct ggattattcc atcctcaacg ataacggctc
    26161 catgtttaac acgccgccga catttgcctg gtatctatct ggtctggtct ttaaatggct
    26221 gaaagcgaac ggcggtgtag ctgaaatgga taaaatcaat cagcaaaaag cagaactgct
    26281 atatggggtg attgataaca gcgatttcta ccgcaatgac gtggcgaaag ctaaccgttc
    26341 gcggatgaac gtgccgttcc agttggcgga cagtgcgctt gacaaattgt tccttgaaga
    26401 gtcttttgct gctggccttc atgcactgaa aggtcaccgt gtggtcggcg gaatgcgcgc
    26461 ttctatttat aacgccatgc cgctggaagg cgttaaagcg ctgacagact tcatggttga
    26521 gttcgaacgc cgtcacggtt aatgccgaaa ttttgcttaa tccccacagc cagcctgtgg
    26581 ggtttttatt tctgttgtag agagttgagt tcatggaatc cctgacgtta caacccatcg
    26641 ctcgtgtcga tggcactatt aatctgcccg gttccaagag cgtttctaac cgcgctttat
    26701 tgctggcggc attagcacac ggcaaaacag tattaaccaa tctgctggat agcgatgacg
    26761 tgcgccatat gctgaatgca ttaacagcgt taggggtaag ctatacgctt tcagccgatc
    26821 gtacgcgttg cgaaattatc ggtaacggcg gtccattaca cgcagaaggt gccctggagt
    26881 tgttcctcgg taacgccgga acggcaatgc gtccgctggc ggcagctctt tgtctgggta
    26941 gcaatgatat tgtgctgacc ggtgagccgc gtatgaaaga acgcccgatt ggtcatctgg
    27001 tggatgcgct gcgcctgggc ggggcgaaga tcacttacct ggaacaagaa aattatccgc
    27061 cgttgcgttt acagggcggc tttactggcg gcaacgttga cgttgatggc tccgtttcca
    27121 gccaattcct caccgcactg ttaatgactg cgcctcttgc gccggaagat acggtgattc
    27181 gtattaaagg cgatctggtt tctaaacctt atatcgacat cacactcaat ctgatgaaga
    27241 cgtttggtgt tgaaattgaa aatcagcact atcaacaatt tgtcgtaaaa ggcgggcagt
    27301 cttatcagtc tccgggtact tatttggtcg aaggcgatgc atcttcggct tcttactttc
    27361 tggcagcagc agcaatcaaa ggcggcactg taaaagtgac cggtattgga cgtaacagta
    27421 tgcagggtga tattcgcttt gctgatgtgc tggaaaaaat gggcgcgacc atttgctggg
    27481 gcgatgatta tatttcctgc acgcgtggtg aactgaacgc tattgatatg gatatgaacc
    27541 atattcctga tgcggcgatg accattgcca cggcggcgtt atttgcaaaa ggcaccacca
    27601 cgctgcgcaa tatctataac tggcgtgtta aagagaccga tcgcctgttt gcgatggcaa
    27661 cagaactgcg taaagtcggc gcggaagtgg aagaggggca cgattacatt cgtatcactc
    27721 ctccggaaaa actgaacttt gccgagatcg cgacatacaa tgatcaccgg atggcgatgt
    27781 gtttctcgct ggtggcgttg tcagatacac cagtgacgat tcttgatccc aaatgcacgg
    27841 ccaaaacatt tccggattat ttcgagcagc tggcgcggat tagccaggca gcctgaatga
    27901 acaacgggca ataaatagcc aaatctttct ttatcaaaac gtcggcacat tgtcggcgtt
    27961 ttttttcgga ccttgtgagt cattttgatt aatggtagcg tcgcttgtca atgtaagttg
    28021 ttgatacata atatttatat atgattaatc aacggatgat tcacatgaag aatactaaat
    28081 tactgctggc gattgcgacc tctgcagcat tactgacagg gtgtcaaaat acccacggta
    28141 ttgataccaa tatggctatc agctccggtt taaatgccta taaagcagca acattaagcg
    28201 atgccgatgc aaaagcgatt gccaatcagg gctgtgccga aatggacagc ggcaatcaag
    28261 tcgcaagtaa atccagcaag tacggtaaac gtctggcaaa aatcgccaaa gcattgggta
    28321 acaatattaa tggcacgccg gtcaactata aggtttatat gaccagcgac gtcaacgcat
    28381 gggcgatggc gaacggctgt gttcgtgtct acagtggcct gatggacatg atgaatgaca
    28441 acgaaattga aggcgttctg ggccatgaac tgggccacgt cgcgttgggt cactcgctgg
    28501 ctgaaatgaa agcttcttat gcgatcgttg ccgcacgcga tgccatttca gctaccagcg
    28561 gtgtggcttc ccagctttcc cgctcacaat taggtgatat cgcagaaggc gctatcaatg
    28621 ctaaatactc ccgtgataaa gagtccgaag cagatgattt ctcctttgat ctgttgaaga
    28681 aacgtggcat cagcacccag gggctggttg gcagctttga aaaactggct agcctggatg
    28741 gcggtcgcac ccagtccatg tttgactctc acccaccatc aacagagcgt gcgcaacaca
    28801 tccgtgatcg tatcgcctct ggtaagtaaa tcattgtcat ctttcgggct ggtcttctgc
    28861 cagcccgcta taattgcgca ataaatcccc atctgaatac agacaaaact ggtttttgca
    28921 cacaacgtta acgatttgtg gcgtcggcgc gtataatgcg cgcggttatg ttaacggtac
    28981 gcctgtttta aggagataaa gatgacggca attgccccgg ttattaccat tgatggccca
    29041 agcggtgcag ggaaaggcac cttgtgtaag gctatggcgg aagcgttgca atggcatctg
    29101 ctggactcgg gtgcaattta tcgcgtactg gcattggcgg cattacatca ccatgttgat
    29161 gttgcgtcgg aagatgcgct ggtaccgctg gcatcccatc tggatgtacg ttttgtgtcg
    29221 accaatggca atctggaagt gatcctcgaa ggggaagatg tcagcggcga aattcgtact
    29281 caggaagtgg cgaatgcagc ttcacaagtc gcggcattcc cacgcgttcg tgaagcatta
    29341 ttgcgtcgcc aacgcgcgtt tcgcgaatta ccaggtctga ttgccgatgg ccgcgacatg
    29401 ggaacggtgg tattccctga tgcaccagtg aaaattttcc ttgacgcctc ctcggaagaa
    29461 cgtgcgcatc gccgcatgct acagttgcag gagaagggct ttagtgttaa ctttgagcgc
    29521 cttttggccg agatcaaaga acgcgacgac cgcgatcgta accgagcggt agcgccactg
    29581 gttccggcag ccgatgcttt agtgttggat tccaccacct taagcattga gcaagtgatt
    29641 gaaaaagcgc tacaatacgc gcgccagaaa ttggctctcg cataagcgac cgaatttgca
    29701 gtacccccgt tgcaatggaa tgacagcggg tatgttaaac aaccccatcc ggcatggagc
    29761 caggtggacg ttaaatataa acctgaagat taaacatgac tgaatctttt gctcaactct
    29821 ttgaagagtc cttaaaagaa atcgaaaccc gcccgggttc tatcgttcgt ggcgttgttg
    29881 ttgctatcga caaagacgta gtactggttg acgctggtct gaaatctgag tccgccatcc
    29941 cggctgagca gttcaaaaac gcccagggcg agctggaaat ccaggtaggt gacgaagttg
    30001 acgttgctct ggacgcagta gaagacggct tcggtgaaac tctgctgtcc cgtgagaaag
    30061 ctaaacgtca cgaagcctgg atcacgctgg aaaaagctta cgaagatgct gaaactgtta
    30121 ccggtgttat caacggcaaa gttaagggcg gcttcactgt tgagctgaac ggtattcgtg
    30181 cgttcctgcc aggttctctg gtagacgttc gtccggtgcg tgacactctg cacctggaag
    30241 gcaaagagct tgaatttaaa gtaatcaagc tggatcagaa gcgcaacaac gttgttgttt
    30301 ctcgtcgtgc cgttatcgaa tccgaaaaca gcgcagagcg cgatcagctg ctggaaaacc
    30361 tgcaggaagg catggaagtt aaaggtatcg ttaagaacct cactgactac ggtgcattcg
    30421 ttgatctggg cggcgttgac ggcctgctgc acatcactga catggcctgg aaacgcgtta
    30481 agcatccgag cgaaatcgtc aacgtgggcg acgaaatcac tgttaaagtg ctgaagttcg
    30541 accgcgaacg tacccgtgta tccctgggcc tgaaacagct gggcgaagat ccgtgggtag
    30601 ctatcgctaa acgttatccg gaaggtacca aactgactgg tcgcgtgacc aacctgaccg
    30661 actacggctg cttcgttgaa atcgaagaag gcgttgaagg cctggtacac gtttccgaaa
    30721 tggattggac caacaaaaac atccacccgt ccaaagttgt taacgttggc gatgtagtgg
    30781 aagttatggt tctggatatc gacgaagaac gtcgtcgtat ctccctgggt ctgaaacagt
    30841 gcaaagctaa cccgtggcag cagttcgcgg aaacccacaa caagggcgac cgtgttgaag
    30901 gtaaaatcaa gtctatcact gacttcggta tcttcatcgg cctggacggc ggcatcgacg
    30961 gcctggttca cctgtctgac atctcctgga acgttgcagg cgaagaagca gttcgtgaat
    31021 acaaaaaagg cgacgaaatc gctgcagttg ttctgcaggt tgacgcagaa cgtgaacgta
    31081 tctccctggg cgttaaacag ctcgcagaag atccgttcaa caactgggtt gctctgaaca
    31141 agaaaggcgc tatcgtaacc ggtaaagtaa ctgcagttga cgctaaaggc gcaaccgtag
    31201 aactggctga cggcgttgaa ggttacctgc gtgcttctga agcatcccgt gaccgcgttg
    31261 aagacgctac cctggttctg agcgttggcg acgaagttga agctaaattc accggcgttg
    31321 atcgtaaaaa ccgcgcaatc agcctgtctg ttcgtgcgaa agacgaagct gacgagaaag
    31381 atgcaatcgc aactgttaac aaacaggaag atgcaaactt ctccaacaac gcaatggctg
    31441 aagctttcaa agcagctaaa ggcgagtaat tctctgactc ttcgggattt ttattccgaa
    31501 gtttgttgag tttacttgac agattgcagg tttcgtcctg taatcaagca ctaagggcgg
    31561 ctacggccgc ccttaatcaa tgcagcaaca gcagccgctt aatttgcctt taaggaaccg
    31621 gaggaatcat gaccaagtca gaattgatag aaagacttgc cacccagcaa tcgcacattc
    31681 ccgccaagac ggttgaagat gcagtaaaag agatgctgga gcatatggcc tcgactcttg
    31741 cgcagggcga gcgtattgaa atccgcggtt tcggcagttt ctctttgcac taccgcgcac
    31801 cacgtaccgg acgtaatccg aagactggcg ataaagtaga actggaagga aaatacgttc
    31861 ctcactttaa acctggtaaa gaactgcgcg atcgcgccaa tatttacggt taagtttttt
    31921 actcaaactt gaacgagaga aaagcacctg tcgggtgctt ttttcatttc tctaatctgg
    31981 aactggaagc tgcctcgcag agttttgaac agttttcacc ctttcgttaa attcttctga
    32041 atatgcctcg gggaacgcaa aattcccacc agacaaccgc tcaacaaagt tgcacacttt
    32101 ccataaacag ggaggggtgc atgaaaataa cgacagtcgg tgtatgcata attagcggaa
    32161 tttttccgtt gctgattttg ccccaattgc ctgggacatt aacccttgcg tttctgactc
    32221 tcttcgcctg cgtactggca tttatccctg ttaaaaccgt ccgttatatc gcgctgacgt
    32281 tgctgttttt cgtttggggc atattatcag caaagcaaat tttgtgggca ggagaaacct
    32341 taactggcgc gacgcaggat gcaattgttg agatcactgc aactgacggc atgaccactc
    32401 attacggtca aattactcat ctacaaggtc gacgtatatt ccctgcgtca ggtctcgtga
    32461 tgtatggcga atatcttccg caagcggttt gtgctggaca acaatggtca atgaaactca
    32521 aagttcgtgc agttcatggc caacttaatg atggcggctt tgatagccag cgttatgcca
    32581 ttgcccagca tcagccgctc accggccgtt ttctgcaggc aagtgtcatt gaaccgaatt
    32641 gtagcctgcg tgcacagtat ctggcgtcac tacaaacaac gctgcaaccc tatccgtgga
    32701 atgcggttat tcttggttta ggtatggggg aacggttatc cgtccccaaa gaaatcaaaa
    32761 atatcatgcg cgatactgga acggcgcatt taatggcgat atcgggattg cacatcgctt
    32821 ttgcggcgtt gctggctgcc ggactcattc gcagtggaca aatttttctg cctgggcgct
    32881 ggatccactg gcaaatacca ttaattggcg gaatctgctg tgctgctttt tatgcctggt
    32941 tgacgggaat gcaacctcct gcattgcgta ccatggtggc gcttgctacg tggggaatgc
    33001 ttaagttaag tgggcgacag tggagtggct gggatgtatg gatatgttgt ctggcggcaa
    33061 ttttgctgat ggatcctgtt gccattctct cgcaaagttt atggctctct gccgctgcgg
    33121 tcgcggcatt gatattttgg tatcagtggt ttccctgtcc tgagtggcaa ctgccgccgg
    33181 tattgcgtgc agttgtttcc ctcatccatc tgcaactggg aatcacactt ctgcttatgc
    33241 ccgtgcaaat cgtcatattt catggcatta gtctgacctc gtttattgca aatctattag
    33301 caattccctt ggtgacattt atcacggttc cgttgatcct cgccgcgatg gttgtgcatt
    33361 taagcgggcc gttaatcctg gagcaagggt tatggtttct tgccgaccgg tctttggctt
    33421 tacttttctg ggggttaaag agtttgccgg aagggtggat caacattgct gaatgttggc
    33481 aatggctatc attttcccca tggttcttac tggtggtatg gcgattaaac gcctggcgaa
    33541 cgttgccagc aatgtgtgtg gctggaggct tgctgatgtg ctggccgctg tggcaaaaac
    33601 ctcgacctga cgagtggcag ctgtacatgc ttgatgtcgg gcaagggctg gcaatggtga
    33661 tagccagaaa cggcaaagcg attctctatg acacaggact ggcctggcct gaaggggata
    33721 gtgggcaaca actgattatc ccctggctcc actggcataa tcttgaaccg gaaggcgtta
    33781 ttctgagcca tgaacatctg gatcaccggg gagggctgga ttcaatattg catatatggc
    33841 cgatgttatg gatcagaagt ccgttaaact gggaacatca tcagccctgt gtgcgtggcg
    33901 aagcgtggca atggcaagga ttgcgtttca gcgcgcactg gcctttacaa ggtagcaacg
    33961 ataaaggaaa taaccattcc tgtgtggtta aggttgatga cgggacgaat agcattcttc
    34021 taaccggtga tattgaagcc ccagctgaac aaaagatgct aagccgttac tggcagcaag
    34081 tgcaggcaac attgcttcag gtacctcacc atggcagtaa tacctcatca tcgttgccat
    34141 taattcagcg agtgaatgga aaagtggcac tcgcatcggc atcgcgctat aacgcatggc
    34201 gactgccctc taacaaagtt aagcatcgct atcaactgca aggatatcaa tggattgata
    34261 ctccacatca aggtcaaaca acggtcaatt tttcagcgca aggctggcgg attagcagcc
    34321 tcagggagca aattttacct cgttggtatc atcagtggtt tggcgtgcca gtggataacg
    34381 ggtagaatat gcggctattt caacaaatgc tggttttttg aatgcataac gacaaagatc
    34441 tctctacgtg gcagacattc cgccgactgt ggccaaccat tgcgcctttc aaagcgggtc
    34501 tgatcgtggc gggcgtagcg ttaatcctca acgcagccag cgataccttc atgttatcgc
    34561 tccttaagcc acttcttgat gatggctttg gtaaaacaga tcgctccgtg ctggtgtgga
    34621 tgccgctggt ggtgatcggg ctgatgattt tacgtggtat caccagctat gtctccagct
    34681 actgtatctc ctgggtatca ggaaaggtgg taatgaccat gcgtcgccgc ctgtttggtc
    34741 acatgatggg aatgccagtt tcattctttg acaaacagtc aacgggtacg ctgttgtcac
    34801 gtattaccta cgattccgaa caggttgctt cttcttcttc cggcgcactg attactgttg
    34861 tgcgtgaagg tgcgtcgatc atcggcctgt tcatcatgat gttctattac agttggcaac
    34921 tgtcgatcat tttgattgtg ctggcaccga ttgtttcgat tgcgattcgc gttgtatcga
    34981 agcgttttcg caacatcagt aaaaacatgc agaacaccat ggggcaggtg accaccagcg
    35041 cagaacaaat gctgaagggc cacaaagaag tattgatttt cggtggtcag gaagtggaaa
    35101 cgaaacgctt tgataaagtc agcaaccgaa tgcgtcttca ggggatgaaa atggtttcag
    35161 cctcttccat ctctgatccg atcattcagc tgatcgcctc tttggcgctg gcgtttgttc
    35221 tgtatgcggc gagcttccca agtgtcatgg atagcctgac tgccggtacg attaccgttg
    35281 ttttctcttc aatgattgca ctgatgcgtc cgctgaaatc gctgaccaac gttaacgccc
    35341 agttccagcg cggtatggcg gcttgtcaga cgctgtttac cattctggac agtgagcagg
    35401 agaaagatga aggtaagcgc gtgatcgagc gtgcgactgg cgacgtggaa ttccgcaatg
    35461 tcacctttac ttatccggga cgtgacgtac ctgcattgcg taacatcaac ctgaaaattc
    35521 cggcagggaa gacggttgct ctggttggac gctctggttc gggtaaatca accatcgcca
    35581 gcctgatcac gcgtttttac gatattgatg aaggcgaaat cctgatggat ggtcacgatc
    35641 tgcgcgagta taccctggcg tcgttacgta accaggttgc tctggtgtcg cagaatgtcc
    35701 atctgtttaa cgatacggtt gctaacaaca ttgcttacgc acggactgaa cagtacagcc
    35761 gtgagcaaat tgaagaagcg gcgcgtatgg cctacgccat ggacttcatc aataagatgg
    35821 ataacggtct cgatacagtg attggtgaaa acggcgtgct gctctctggc ggtcagcgtc
    35881 agcgtattgc tatcgctcga gccttgttgc gtgatagccc gattctgatt ctggacgaag
    35941 ctacctcggc tctggatacc gaatccgaac gtgcgattca ggcggcactg gatgagttgc
    36001 agaaaaaccg tacctctctg gtgattgccc accgcttgtc taccattgaa aaggcagacg
    36061 aaatcgtggt cgtcgaggat ggtgtcattg tggaacgcgg tacgcataac gatttgcttg
    36121 agcaccgcgg cgtttacgcg caacttcaca aaatgcagtt tggccaatga tcgaaaaaat
    36181 ctggtctggt gaatcccctt tgtggcggct attgctgcca ctctcctggt tgtatggcct
    36241 ggtgagtggc gcgatccgtc tttgctataa actaaaactg aagcgcgcct ggcgtgcccc
    36301 cgtaccggtt gtcgtggttg gtaatctcac cgcaggcggc aacggaaaaa ccccggtcgt
    36361 tgtctggctg gtggaacagt tgcaacagcg cggtattcgc gtgggggtcg tatcgcgggg
    36421 atatggtggt aaggctgaat cttatccgct gttattgtcg gcagatacca caacagcaca
    36481 ggcgggtgat gaacctgtgt tgatttatca acgcactgat gcgcctgttg cggtttctcc
    36541 cgttcgttct gatgcggtaa aagccattct ggcgcaacac cctgatgtgc agatcatcgt
    36601 aaccgacgac ggtttacagc attaccgtct ggcgcgtgat gtggaaattg tcgttattga
    36661 tggtgtgcgt cgctttggca atggctggtg gttgccggcg gggccaatgc gtgagcgagc
    36721 ggggcgctta aagtcggttg atgcggtaat cgtcaacggc ggtgtccctc gcagcggtga
    36781 aatccccatg catctgctgc cgggtcaggc ggtgaattta cgtaccggta cgcgttgtga
    36841 cgttgctcag cttgaacatg tagtggcgat ggcggggatt gggcatccgc cgcgcttttt
    36901 tgccacgctg aagatgtgtg gcgtacaacc ggaaaaatgt gtaccgctgg ccgatcatca
    36961 gtctttgaac catgcggatg tcagtgcgtt ggtaagcgcc gggcaaacgc tggtaatgac
    37021 tgaaaaagat gcggtgaaat gccgggcctt tgcagaagaa aattggtggt atttgcctgt
    37081 agacgcacag ctttcaggtg atgaaccagc gaaactgctt acgcaactaa ccttgctggc
    37141 ttctggcaac tagttacgcc gcggcagcgt tcgattgatg gagtcatgaa tgtcgctgcc
    37201 gcacctctcc cttgctgatg cgcgtaatct tcaccttgcc gcacaaggcc tgttaaacaa
    37261 accccgccgt cgagcgtcgt tggaggatat tccggcaacg atctcccgca tgtccttgct
    37321 gcaaatcgat accatcaata ttgttgcccg tagtccatat ctggtgcttt tcagtcgtct
    37381 gggaaattat cctgcccagt ggctggatga gtctctggcg cgtggcgaat taatggaata
    37441 ctgggcgcat gaagcctgct ttatgccgcg tagcgacttt cgtcttattc gccaccgcat
    37501 gctggcacct gaaaaaatgg gctggaaata caaagacgcc tggatgcagg aacatgaggc
    37561 ggaaattgca cagttaattc agcatattca tgataagggg ccggtacgtt cagccgattt
    37621 tgagcatcct cgtaaaggtg caagcggctg gtgggaatgg aagccgcata aacggcatct
    37681 ggaaggttta tttactgccg gaaaggtgat ggtgattgaa cggcgcaact tccagcgcgt
    37741 ttatgattta acccaccgtg tcatgcctga ctgggatgat gagcgcgatc tcgtttcgca
    37801 aacagaagca gaaatcatca tgctggataa cagtgcgcgt agcctgggaa tattccgcga
    37861 acagtggctg gcagattact atcggctgaa acgtccggca ctggcggcgt ggcgcgaagc
    37921 gagggctgaa cagcagcaaa tcattgctgt gcatgttgaa aaattgggca atctttggct
    37981 gcatgatgat ttgctgccgc tactcgagcg agcgctggcc ggaaagctca ctgcaacgca
    38041 cagcgcggta ctttcgcctt ttgatcctgt tgtctgggat cgcaaacgcg cagagcagct
    38101 ttttgatttt agctaccggc tggagtgcta taccccagcg ccgaaacgcc agtatggcta
    38161 ttttgttctg ccgttattac atcgtgggca attagttggg cgaatggatg ccaaaatgca
    38221 tcgccagaca ggcatccttg aagttatctc tctgtggtta caggaaggta ttaaaccaac
    38281 gacaacgctg caaaaagggc tacgtcaggc gattactgat ttcgctaact ggcagcaggc
    38341 aacgcgggtg acattaggat gctgcccgca aggcctcttt actgattgcc gcaccggctg
    38401 ggaaatagac cccgtcgcat aaatgattat gataagattt atgcattcat aacccgatcc
    38461 atctggagga actatggatc atcgtctgct tgaaatcatt gcctgcccgg tttgcaacgg
    38521 aaaactttgg tataaccagg aaaaacaaga gcttatttgc aaactggaca acctcgcttt
    38581 cccgctgcgt gatggcattc cagtgttgct ggaaacggaa gcccgcgtgc tgactgctga
    38641 tgagagtaaa tcatgagttt tgtggtcatt attcccgcgc gctacgcgtc cacgcgtctg
    38701 cccggtaaac cattggttga tattaacggc aaacccatga ttgttcatgt tcttgaacgc
    38761 gcgcgtgaat caggtgccga gcgcatcatc gtggcaaccg atcatgagga tgttgcccgc
    38821 gccgttgaag ccgctggcgg tgaagtatgt atgacgagcg ccgatcatca gtcaggaaca
    38881 gaacgtctgg cggaagttgt cgaaaaatgc gcattcagcg acgacacggt gatcgttaat
    38941 gtgcagggtg atgaaccgat gatccctgcg acaatcattc gtcaggttgc tgataacctc
    39001 gctcagcgtc aggtgggtat ggcgactctg gcggtgccaa tccacaatgc ggaagaagcg
    39061 tttaacccga atgcggtgaa agtggttctc gacgctgaag ggtatgcact gtacttctct
    39121 cgcgccacca ttccttggga tcgtgatcgt tttgcagaag gccttgaaac cgttggcgat
    39181 aacttcctgc gtcatcttgg tatttatggc taccgtgcag gctttatccg tcgttacgtc
    39241 aactggcagc caagtccgtt agaacacatc gaaatgttag agcagcttcg tgttctgtgg
    39301 tacggcgaaa aaatccatgt tgctgttgct caggaagttc ctggcacagg tgtggatacc
    39361 cctgaagatc ttgagcgcgt tcgcgctgaa atgcgctaat ttcacttcac gacacttcag
    39421 ccaattttgg gaggagtgtc gtaccgttac gattttcctc aatttttctt ttcaacaatt
    39481 gatctcattc aggtgacatc ttttatattg gcgctcatta tgaaagcagt agcttttatg
    39541 agggtaatct gaatggaaca gctgcgtgcc gaattaagcc atttactggg cgaaaaactc
    39601 agtcgtattg agtgcgtcaa tgaaaaagcg gatacggcgt tgtgggcttt gtatgacagc
    39661 cagggaaacc caatgccgtt aatggtaaga agctttagta cgcccggaaa agcccgacaa
    39721 ctggcatgga aaaccaccat gctggcaaga agtgggactg tccgtatgcc gactatttat
    39781 ggtgtgatga cgcatgaaga acaccccggc cccgatgtcc tgctactgga gcggatgcgt
    39841 ggtgtttcgg tggaggcacc agcccgaaca ccagaacgct gggaacaact caaagaccaa
    39901 atcgttgaag ccttactggc ctggcaccgt caggacagtc gcggttgcgt cggcgcggtc
    39961 gacaatactc aggaaaattt ctggccctca tggtaccggc aacatgttga agtgctatgg
    40021 accacgctca atcagttcaa taacaccggt ctgacgatgc aggataagcg gatcctgttt
    40081 cgcactcgcg aatgtctccc ggcattattt gaaggcttta acgacaattg tgtgctgatt
    40141 cacggtaact tctgtttacg cagcatgttg aaagattcgc gcagcgatca gttactggcg
    40201 atggtcgggc cgggactaat gctttgggca ccgcgagaat acgaactgtt ccgactaatg
    40261 gataattctc tggcggaaga tttgctctgg agttacctgc aacgcgcgcc agtggcggag
    40321 tcgttcatct ggcggcgttg gttgtatgtg ttatgggatg aagttgcgca actggttaat
    40381 accggacgat ttagtcggcg caacttcgat ctggcatcaa aatcactctt gccgtggctc
    40441 gcctgacgaa ccttttagcc actgccagat acggccaagc gtttcatagc caacacgatc
    40501 gctatgcatc aaccagaccg gagaagggat tgcccgttcc cacgggttaa gcggcgagtc
    40561 gatggccaac tgattcgccg gggctggtag cggatttaac ccttcctgct gaaaaaagat
    40621 catcgcccgc ggcagatgtg atgcggaggt caccagcagg aaaggggcgt caccaatcgc
    40681 ctgtttcact gctgcagctt cttcttcggt atcttttggc aaatccaggg tgataatttg
    40741 ctcgcgcggc acgcccagcg attgcgcaac tctggcacct acttccgctg tactcaccgt
    40801 attggttttt gctacgcctc ccgtgaagat cagttttgat cccggatttt cgcgccataa
    40861 gcgaatacct tcattcaggc gtggcagact gttattgatt aaattagagc tcggtgccca
    40921 ctgcgggttc caggtataac cacctccgag caccacgata tagtccactt tttgcgaatt
    40981 attccatgtc ggataggtgc tttcgatggg acgcagcagg cggtcggcta ccggttgcaa
    41041 actcaataac aagagcgcca gccacccaat gctaataaaa atcttcccgg ttttttgaaa
    41101 acggctaaac cacagcagcg ccaggccagc gccaataatc aacaacatca gcggaagtgg
    41161 cagcaacata ttgccaatca cttttttcag tgtaaaaagc atcctttctg gttccttttt
    41221 taaccatata gcaagggatc gccagcgata ttacaccaga cgggttcatt ctcgccgtgg
    41281 ctgtgacaaa atagcgtctt tatcagaaaa cgtcttagcc aaccggtgga gaaagcaatg
    41341 caggatcgca attttgatga tattgcggaa aagttttccc gtaacattta cggcaccacc
    41401 aaagggcagc ttcgacaggc tattctgtgg caggatctcg atcgcgtgct ggcggaaatg
    41461 ggcccgcaaa aactgcgtgt gctggatgct ggcggtggag aagggcagac cgcaatcaaa
    41521 atggccgagc gtgggcatca ggtcatttta tgcgatcttt ctgcgcagat gatcgaccgc
    41581 gcaaaacagg cggcagaagc aaaaggtgtg agcgacaaca tgcaatttat acattgcgcc
    41641 gctcaggatg ttgcttcgca tttggaaacg cccgttgatc tgatattgtt ccatgcggtg
    41701 ctcgagtggg tggctgatcc ccgcagcgta ttgcagaccc tctggtcagt gttgcgtcca
    41761 ggcggcgtgt tgtcgttaat gttctacaat gcgcatggtt tgttgatgca taacatggtc
    41821 gccgggaatt ttgattacgt gcaggcggga atgccgaaaa agaaaaaacg gacgctttcg
    41881 ccagattatc cacgcgaccc ggcgcaggtt tatctgtggc tggaagaagc tggttggcaa
    41941 attatgggta agacaggcgt tcgcgtgttt catgattatc tgcgcgagaa acaccagcag
    42001 cgcgactgct atgaagcatt acttgaatta gaaacgcgtt attgccgtca ggaaccgtat
    42061 attaccctgg ggcgttatat tcatgtcacc gcgcgcaaac cgcagagcaa ggataaagta
    42121 tgagtgaatt ttcccagaca gtccccgaac tggttgcctg ggccagaaaa aatgacttct
    42181 ccatctcgct gccggtagac cgactctctt ttctgctggc ggttgccacg ctgaacggcg
    42241 agcgtctgga tggtgagatg agtgaaggcg agctggtgga tgcattccgc catgtgagtg
    42301 atgcgtttga gcaaaccagc gaaaccatcg gcgtgcgcgc caataacgcg atcaacgaca
    42361 tggtgcgtca acgtctgctg aaccgcttta ccagcgagca ggcggaaggg aacgcaattt
    42421 accgtctgac gccgctcggc atcggcatta ctgactacta catccgtcag cgcgagtttt
    42481 ctacgctgcg tctttctatg cagttgtcga ttgtggcggg tgagctcaaa cgcgcagcag
    42541 atgccgccga agagggcggt gatgaatttc actggcaccg taatgtctat gcgccactga
    42601 aatattcggt agcagaaatt ttcgacagta tcgacctgac gcaacgtctg atggacgaac
    42661 agcagcagca ggtgaaggac gatatcgccc agttgctgaa caaagactgg cgggcggcga
    42721 tttccagctg tgaattgttg ctttcggaaa cttccggaac gctgcgtgaa ttgcaggata
    42781 cgctggaagc ggcaggcgac aaattgcagg ctaatctgtt gcgcattcag gatgcgacga
    42841 tgacccatga cgatctgcat ttcgtcgatc gtctggtgtt cgatctgcag agcaaactcg
    42901 atcgtattat cagttggggc cagcaatcca tcgacttgtg gattggctac gaccgccacg
    42961 tacacaaatt tattcgtacc gcgatcgata tggataaaaa ccgcgtcttt gctcagcggt
    43021 tacgtcagtc ggtacaaacc tattttgatg agccgtgggc gctaacttat gccaatgccg
    43081 atcgtctgct ggatatgcgt gacgaagaga tggcactgcg cgatgaagaa gtgactgggg
    43141 aacttcctga ggatctggaa tacgaagagt ttaacgagat ccgcgaacag ctggcggcga
    43201 tcatcgaaga acaacttgcc gtgtacaaaa ccagacaagt gccgctggat cttggtctgg
    43261 tggtacgcga atatctgtca cagtatccgc gtgcacgtca ctttgacgtt gcgcgtattg
    43321 ttattgatca ggcggtacgt cttggcgtag cgcaagcaga tttcaccgga ctgccagcga
    43381 aatggcagcc gattaatgat tacggagcca aggtacaggc gcatgtcatc gacaaatatt
    43441 gaacaagtga tgccggttaa gctggcgcag gcgctggcga atccgttatt tccggcgctg
    43501 gacagcgcct tacgttcagg acgccatatt ggcctcgacg aactggataa tcatgcattc
    43561 ctgatggatt ttcaggaata tctggaagag ttttacgcgc gttataacgt tgagcttatt
    43621 cgcgcaccag aagggttctt ctatttacgc ccacgttcca ccacgctgat ccctcgttcc
    43681 gtcttgtcgg aactggatat gatggtcggg aaaatcctct gttatctcta tctcagcccg
    43741 gaacggctgg cgaatgaggg gattttcacc cagcaggaac tgtacgacga actgctcacc
    43801 ctggccgatg aagcaaaact gctgaaactg gtgaacaacc gttcaaccgg ttcagacgtt
    43861 gaccgtcaga agttgcagga gaaagtacgt tcttcgctca accgtctgcg tcgtttaggc
    43921 atggtgtggt ttatgggcca cgacagcagc aagtttcgca ttaccgaatc ggtgttccgc
    43981 ttcggagccg atgtgcgtgc tggcgacgat ccccgtgaag cacagcgtcg cctgattcgt
    44041 gatggcgaag caatgccgat tgaaaatcat ctgcaactca acgatgaaac cgaagagaat
    44101 cagccagata gcggagagga agaataatga ttgaacgcgg taaatttcgc tcactgacgc
    44161 tgattaactg gaacggcttt tttgcccgaa cttttgacct tgacgagctg gtcacgacgc
    44221 tttctggcgg taacggggcg ggtaaatcca ccaccatggc ggcgttcgtt acggcgctga
    44281 tccccgacct gaccctgctg catttccgta acactacgga agccggggcc accagcggtt
    44341 cgcgcgataa aggtctgcac ggtaagctga aagcgggtgt ctgttattcg atgctcgaca
    44401 ccattaactc gcgccaccag cgcgtggtgg tcggtgtgcg tctgcaacag gttgccggac
    44461 gcgatcgtaa agtggatatc aagccgtttg ccattcaggg actgccgatg tcggtgcagc
    44521 cgacacagct ggtgaccgaa accctgaacg aacgccaggc gcgcgtgctg ccgcttaacg
    44581 agctgaaaga caagctcgag gcgatggaag gcgtgcagtt taaacagttc aactccatta
    44641 ctgattacca ctcgctgatg ttcgatctgg gcatcatcgc gcgtcgtctg cgctccgcat
    44701 ctgaccgtag caaattctat cgtctgatcg aagcttcgct gtatggcggg atctccagtg
    44761 ccattacccg ttctctgcgc gactacctgt tgccagaaaa cagcggcgtg cgtaaagcgt
    44821 tccaggacat ggaagcggcg ctgcgtgaaa accgtatgac gctggaagcg attcgtgtca
    44881 cccagtcgga ccgcgacctg tttaagcatc tgatcagcga agccaccaac tacgtggcgg
    44941 cggactacat gcgtcacgcc aacgagcgcc gtgtccatct cgacaaagcc ctggagtttc
    45001 gtcgcgagct acatacttcg cgtcagcaac tggcggctga gcagtacaaa cacgtcgata
    45061 tggcgcgtga gctggcagag cacaacggtg ccgaaggcga tctggaagcg gattatcagg
    45121 cggccagtga tcacctgaac ctggtgcaaa ccgcactgcg tcagcaggag aagatcgaac
    45181 gctacgaagc ggatctcgat gagctgcaga tccgtctgga agagcaaaat gaagtggtgg
    45241 cagaagccat cgaacgccag gaagagaatg aggctcgtgc ggaagctgcc gaactggaag
    45301 tggacgagct gaaaagccag cttgctgact accagcaggc gctggacgtc cagcaaacgc
    45361 gcgcgatcca gtataaccag gcgattgctg cgcttaatcg tgccaaagaa ctgtgccatc
    45421 tgccggactt aaccgccgac tgcgccgccg aatggctgga aaccttccag gcgaaagagc
    45481 tggaagcgac tgaaaaaatg ctctctcttg agcagaaaat gagcatggcg caaaccgcgc
    45541 acagccagtt tgagcaggct tatcagctgg tggtggcaat caacggccca ctggcgcgta
    45601 acgaggcgtg ggatgtcgct cgcgaactat tgcgcgaagg ggtcgatcag cgtcacctgg
    45661 cagagcaggt tcagccgctg cggatgcgat taagcgaact ggaacagcgt ctacgcgagc
    45721 agcaagaagc tgagcgtctg ctggcagatt tctgcaaacg tcagggcaag aattttgata
    45781 tcgacgaact ggaagccctg catcaggaac tggaagcacg cattgcctct ctttccgata
    45841 gcgtgtctaa cgcccgtgaa gagcgcatgg cactgtgcca ggagcaggaa cagctgcagt
    45901 ctcgcattca gagtttgatg cagcgtgcgc cggtttggct ggcagcgcaa aacagtctca
    45961 accagttgag cgaacagtgc ggcgaagagt ttacctccag ccaggacgtc accgaatatc
    46021 tgcaacagtt gctggagcgt gagcgagagg cgattgttga acgcgatgaa gtgggcgcgc
    46081 gcaaaaacgc cgtcgatgaa gagatcgaac gtttaagcca gcctggcggc tctgaagatc
    46141 agcgtctgaa cgcgctggcg gagcgttttg gtggtgtgct gctgtcagaa atttatgacg
    46201 acgttagcct ggaagatgcg ccgtacttct cagcgctgta tggcccgtca cgccacgcca
    46261 tcgtggtgcc agatctgtca caggtaactg aacacctgga aggcttgacc gattgcccgg
    46321 aagatctcta tctgatcgaa ggagatccgc agtcattcga tgacagcgtg ttcagcgttg
    46381 atgagctgga aaaagcggta gtggtgaaaa tcgccgatcg tcagtggcgt tattcacgtt
    46441 tcccggaagt gccgctgttt ggtcgtgctg cgcgtgaaag ccgtattgaa agcctccatg
    46501 ccgagcgtga agtgctttcc gaacgcttcg ccacgctctc ctttgatgta cagaaaactc
    46561 agcgtctgca tcaggcgttc agccgcttta tcggcagtca tctggcggtt gcgtttgagt
    46621 ctgacccgga agcagaaatc cgtcaactga acagccgtcg cgtcgaactg gagcgggcgt
    46681 taagtaatca tgaaaatgat aaccagcagc agcgtattca gtttgagcag gcgaaagagg
    46741 gcgttacggc gctgaaccgc attctgccgc gtctcaacct gttggctgat gacagcctgg
    46801 cggatcgcgt cgatgaaatc cgcgaacgtc tggatgaagc ccaggaagcc gcgcgttttg
    46861 ttcagcagtt tggcaatcaa ctggcgaaac tggaaccgat tgtttcggta ttgcagagcg
    46921 acccggaaca gttcgaacag ttaaaagaag attacgcgta ctctcagcag atgcagcgcg
    46981 atgcccgtca gcaggcgttt gccctgacgg aagtggtgca gcgtcgtgcg cactttagct
    47041 attctgactc ggcagaaatg cttagcggta acagcgatct caacgaaaaa ctgcgtgaac
    47101 gtctggaaca ggcggaagcg gagcgtaccc gcgctcgcga agcgttgcgc ggtcacgcag
    47161 cgcagttgag tcagtacaac caggtgctgg cttcgctgaa aagttcttac gacaccaaaa
    47221 aagagctact caacgatctg caacgtgaat tgcaggatat cggcgtgcgt gctgatagcg
    47281 gggcagaaga gcgggcgcgt attcgccgtg acgagctgca tgcgcaactg agcaataacc
    47341 gttcacgccg caatcaactg gaaaaagcgc ttaccttctg cgaagcggag atggacaacc
    47401 tgacccgcaa actgcgcaag ctggagcggg attactttga gatgcgcgag caggtagtga
    47461 ccgccaaagc gggctggtgt gcggtgatgc gcatggtgaa agataacggc gttgagcgcc
    47521 gcttacaccg tcgtgagctg gcttatctct ccgctgatga tttgcgttcc atgtcggata
    47581 aggcgttagg tgcgctgcgt ctggcggtgg cggataacga acatctgcgc gacgtgctgc
    47641 gcatgtcgga agatccgaaa cgtccggagc gtaaaattca gttcttcgtg gcggtttatc
    47701 agcatctgcg tgaacgtatt cgtcaggata ttattcgtac cgatgatccg gtggaagcta
    47761 tcgaacagat ggagattgaa cttagccgtc tgaccgaaga attaacctcc cgtgaacaga
    47821 aactggcgat cagttcccgc agcgtggcga acatcattcg caaaaccatt cagcgcgagc
    47881 agaaccgtat ccgtatgctc aaccaggggt tgcagaacgt atcgtttggt caggtgaaca
    47941 gcgtgcgtct caacgtgaac gtgcgtgaaa cgcacgccat gctactggat gtgctctctg
    48001 aacagcacga gcagcatcag gatctgttta acagcaaccg tttgaccttc tcggaagcgc
    48061 tggcgaaact gtatcaacgt cttaacccgc agattgatat ggggcagcgc acgccgcaga
    48121 ccatcggtga agaactgctg gattaccgca actatctgga aatggaagtt gaggttaacc
    48181 gtggttccga tggctggctg cgcgcagagt ctggtgcatt gtcgaccggt gaggcgattg
    48241 gtaccggtat gtcgattctg gtgatggtgg tacaaagctg ggaagatgaa tctcgccgcc
    48301 tgcgcggtaa agatatctct ccttgccgcc tgctgttcct cgatgaagca gcgcgactgg
    48361 atgctcgttc tatcgccacg ctgtttgaat tgtgtgagcg tttgcaaatg caactcatca
    48421 tcgcagcgcc ggaaaatatc agcccggaga aaggcaccac ctataaactg gtgcgtaaag
    48481 tcttccagaa taccgaacac gttcatgtcg tcggcctgcg aggatttgcg ccgcaactcc
    48541 ctgaaacgct tccaggaact gacgaagcgc cttctcaggc gagttaaaat taaggcggca
    48601 gcaatgccgc cttttctttt tccgaaaact ccgtttctgc actaaaaaag tggcacatta
    48661 cggcgcgctt ttctttaaac ttctttacat taggttatgt aaaaacgtat cggcgtttat
    48721 atactgaaga taagcctgat gagtaacagg cttgctcgtc atactttcgt gagtattggc
    48781 gttgtacagg caagtcgtaa aataacagcc tggctattca gagtatgata aaaacagggg
    48841 gcaagggatg ttgcttaata tgatgtgtgg tcgtcggctg tcggcaatca gtttgtgcct
    48901 ggccgtaaca ttcgctccac tgttcaatgc gcaggccgat gagcctgaag taatccctgg
    48961 cgacagcccg gtggctgtca gtgaacaggg cgaggcactg ccgcaggcgc aagccacggc
    49021 aataatggcg gggatccagc cattgcctga aggtgcggca gaaaaagccc gcacgcaaat
    49081 cgaatctcaa ttacccgcag gttacaagcc ggtttatctt aaccagcttc aactgttgta
    49141 tgccgcacgc gatatgcaac ccatgtggga aaaccgtgat gctgttaaag ccttccagca
    49201 acagctggca gaggtggcga ttgccggttt ccagccgcag tttaataaat gggtagagtt
    49261 actgaccgat cctggtgtta acgggatggc acgcgacgtg gtgctctctg atgcgatgat
    49321 gggctatctc catttcattg caaatattcc ggtcaaaggc actcgctggc tatatagcag
    49381 taaaccttat gcacttgcaa cgccgccgct ctcggtgatt aaccaatggc agctggcgct
    49441 ggataaaggt caattgccta cgtttgttgc aggactggca ccgcagcatc cgcaatatgc
    49501 ggcgatgcat gaatcgttac tggccttact ctgtgacacc aaaccgtggc cccaactgac
    49561 cggcaaagca acgttgcgcc cagggcagtg gagtaacgac gtaccggcgt tgcgcgaaat
    49621 attgcaacgc acaggcatgt tggacggggg gccgaaaatt actctacctg gcgatgacac
    49681 gccaactgac gcggtagtca gcccatccgc tgttactgtt gaaacagcag aaactaagcc
    49741 gatggataag caaacgacgt ctcgtagtaa acctgcgcct gccgttcgcg ccgcctacga
    49801 taatgaactg gtggaagccg ttaaacgttt tcaggcatgg caaggattgg gggcagatgg
    49861 tgctattggc ccggcaacac gtgactggtt aaacgtaacg cccgcccagc gtgctggcgt
    49921 gttggctctc aacatccagc gattgcgctt gctgccaaca gagctttcta ccgggatcat
    49981 ggttaacatt ccggcctatt cgctggtcta ctatcagaac ggcaatcagg tgctggattc
    50041 gcgagtcatt gtcggtcgcc ccgatcgcaa aacgccgatg atgagcagtg cccttaacaa
    50101 cgtagtggta aacccgccgt ggaacgtacc tccaactctg gcacgcaaag atattctgcc
    50161 aaaagtgcgc aacgatccgg gatatctcga aagccatggc tatacggtga tgcgcggctg
    50221 gaacagcaga gaagcgattg acccatggca ggttgactgg tctacaatca cggcctcgaa
    50281 tttaccgttc cgcttccagc aggctccagg cccacggaac tcgctggggc gctataaatt
    50341 caatatgccg agttcagagg ccatttattt gcatgacacg ccgaaccaca atctgttcaa
    50401 gcgtgataca cgcgcattga gctcaggctg tgtacgagtg aataaagctt ccgatctggc
    50461 gaatatgctg ttgcaggatg caggctggaa tgacaaacgt atttctgatg cgctgaagca
    50521 gggtgataca cgttacgtca atattcggca gtcgattccg gtgaatctct actacctgac
    50581 ggcctttgtt ggtgcagatg gtcgtaccca gtatcgtaca gatatttaca attatgatct
    50641 gcctgcgcga tccagctcgc aaatcgtatc gaaagcggaa caattaatca ggtaaatgaa
    50701 gtagttcggg gaaatcagtt gtcgtaataa ttagcatgat tgggggcgat tctctgcagc
    50761 ccccgtcact gctggggttg agtcatcttg acgtctgctt tacgggcggt taaggtgcct
    50821 cttgtgcgcc agaagtgcat ataaacgata acattgacct gtagacttga ttatcatgga
    50881 caaattcgac gctaatcgcc gcaaattgct ggcgcttggt ggcgttgcac tcggtgccgc
    50941 catcctgccg acccctgcgt ttgcaacact ctctacccca cgcccgcgca ttttgacact
    51001 caataatctt cataccggag agtcaatcaa agcggagttt ttcgatggca gaggctatat
    51061 tcaggaagaa ttggcaaaac ttaaccattt tttccgcgat taccgcgcga acaaaataaa
    51121 gtccatcgac ccaggattat tcgaccagtt gtatcgcctg caagggttgt taggcacgcg
    51181 caaaccggtg caactcattt ccggttatcg ttctattgat accaacaatg aactacgcgc
    51241 ccgcagccgt ggagtagcga agaaaagcta tcacactaaa ggccaggcga tggatttcca
    51301 tattgaaggt atcgcgttaa gcaatattcg caaagccgcg ttatctatgc gcgcaggtgg
    51361 tgtaggatat tatccacgta gtaactttgt gcatattgat accgggccag cacggcactg
    51421 gtagtaattg cttaacgaaa caggggcagt atgaactatc gtattattcc ggtcaccgca
    51481 ttctcccaga actgttcatt aatctggtgt gaacaaaccc gtctggccgc actggtcgat
    51541 cctggcggcg atgcggaaaa aatcaaacag gaagttgatg acagcggcct gacactgatg
    51601 cagatcctgc tgacgcatgg tcatctggac cacgttggcg cagcggcgga actggcgcaa
    51661 cattacggcg tgccggtttt cggcccggaa aaagaagatg agttctggct gcaaggcttg
    51721 cctgcgcaaa gtcgtatgtt tggtctggaa gagtgccagc cgctgacgcc agatcgttgg
    51781 ctgaacgaag gcgataccat cagcataggg aatgtgactt tacaggtgtt acattgccct
    51841 gggcatacgc cgggtcatgt cgtgtttttt gatgatcggg caaagctgct gatttctggc
    51901 gatgttattt tcaaaggcgg agtagggcgc agtgacttcc cgcgtggcga tcataatcaa
    51961 ctgatttctt caatcaaaga taaattgctg ccactggggg atgacgtgat atttattccg
    52021 ggtcacggac cattatccac acttggttat gaacgcctgc ataatccctt cctgcaagac
    52081 gaaatgcccg tctggtaagg cacataaaaa agcccgcttt taatgcgggc ctggatttct
    52141 ggcaaagtgc gctttgttta tgccggatgc ggcacgagcg ccttatccgg cctacaaaat
    52201 cgtgcaaatt caaaatattg caggggacgc gtaggcctga taagcgtagc gcatcaggca
    52261 atgttgcgtt tgtcatcagt ctcagcccgc ttttcagcgg gcttcattgt ttttaatgct
    52321 tacagcactg ccacaatcgc ttcgcacagc ggagccatgt tatctggtgt catcccggcc
    52381 acatttacgc gaccagaagc aaccgcatat acgccaaact cttcgcgcag acgcagcact
    52441 tgttcttttg tcaggccact gaaggagaac atgccgttct gtttgatgat aaagctgaag
    52501 tcgcggtttg cgcctttttc ctgcagcgta ttgacgaaca actgacgcat acgctgaata
    52561 cgctggcgca tatcagtcag ctcttgttcc caaatcgcac gtaacgcatc gttgctcagg
    52621 atggtggcaa caacagaagc gccgtgtgct ggtgggttag agtagttagc gcgaatcgcc
    52681 gctttcattt ggctgaatgc gcgatcaacg gtttcactgt cggcagcaac cagagtacaa
    52741 gcgccaacac gctcgttgta caggccaaag tttttagagt aggaactggc aacaatcagc
    52801 tctttatgca tagccgcgaa agcgcgcagt ccttcagcat cttcttccag accacgggca
    52861 aaaccctggt aagcgaagtc aaacagcggt aaccagcctt tctcaacgga gagttgtgcc
    52921 agtgtttgcc attgttccag cgtagggtcg ataccggttg ggttatggca gcagccatgg
    52981 aacagcacta cgtcgccagc ctgagcttca ttcaggctgt taatcagtgc atcgaagtca
    53041 agagtgtgat tttccgcatc ataataagcg tattcacgaa cttccagacc tgcagagtta
    53101 aagacgctct tatggttcgg ccagcttggg ttgctcaccc acacacgctt aacgctggta
    53161 ttttttgcca ggaaatcggc agccacgcgt agtgcgccag tgccccccgg agtctgtgcc
    53221 gtgcgagcac gtttgtcatt gatcagggcg ctacctttac caaacagcag ttcctgagtg
    53281 cagcgaccaa attcagggat gccgtcaatg ccgaggtaat ttttggtggt ttcattttcg
    53341 agcagatact gttcagcctt tttcacgctg gtcagtaccg gggttttgcc cgtctcatct
    53401 ttatagacac caatcccgag gttaattttg ccgggacgtt catcggcacg aaacagatcg
    53461 gccaggccca gaatcgggtc ggcaggagcg gcggtaatgt tctcaaacat gacgaggttc
    53521 cattatggtt acagaaggga agtccgctat cagggtaacg ggagatttac aaaattccaa
    53581 ctattactga tgaaaacgca ggctgttttt gcaagacgtg agattgctct ggaaggtata
    53641 aaaaaaacag gaccaaagtc ctgttttttc ggcatttaac aaagaggtgt gctattagaa
    53701 ctggtaaacg atacccacag caacggtgtc gtctgaacct acgcccagtt tgttgtcaga
    53761 atcgatctgg ttgatgatgt agtcaacata ggtggacatg tttttgttga agtagtaggt
    53821 tgcgcccact tcaaagtagt tcaccagatc aacatcaccg ataccttcta cgtctttcgc
    53881 tttagatttg gtgtaagcga tggacggacg cagaccgaaa tcgaactggt attgcgcaac
    53941 taacagaacg tcttgcgttt tgttggcgaa gccgctggtg tttgtaaatt tattagtgat
    54001 cggcgtagcg ttacgggttt caccgtagtt cgctgccagg tagatgttgt tcgcgtcgta
    54061 cttcagacca gtagcccact gttcagcttt tttaccgttg ccaagaggtt gagcttcttg
    54121 caggttggta cggtcagctg caccataagc accaacgata ccaaagcctt cgtattcgta
    54181 gctgatagaa ccgccaacac cgtcgccgtt agaacggcgt gcagtgtcac gctcgttttt
    54241 acccaggtac tgaacagcga agttcaggcc atcaaccaga ccaaagaagt tggagttacg
    54301 ataggtagca acgccgccaa cacgaccaac gaagaagtca tcgctgtatg cagtatcacc
    54361 accaaattct ggcagcatat cggtgtaacc cagtgcatca taaaccacac cgtagttacg
    54421 gccgtaatcg aaagaaccaa cgtcagcgta tttaagaccc gcgaatgcca gacgcgtttt
    54481 gttaccagtt tgagcgtcag cgccttcaga gttgttaccc tggaagttat attcccactg
    54541 accataaccg gtcagatcgg aattgatttg agtttcccct ttaaaaccaa gacgggcata
    54601 ggtcatgtcg ccattgccac cgtaactgtt ttcaccgtta cccttggaaa aataatgcag
    54661 accaacagct ttaccgtaca gatctacttt gttgccatct ttgttataga tttctgcagc
    54721 gtttgcagta cctgctacta acagagcagg gacgatcact gccagaatat tgcgcttcat
    54781 cattatttat taccctcatg gtttttttta tgacacctgc cactgccgtc aataagttct
    54841 gtcaataaaa atttacggaa ctattgatga gagtttggtg tctttatgtg tctgcaggca
    54901 tctttccatt caaactaacg tttcactacc gtgaaagtgc tacaaagata aagatttggt
    54961 ttcaaaaaga aaaaatatgt aaccaaaagt aaaatttaag gaactttgtg aacaccgtca
    55021 tatttccata gagacgtgat
//
LOCUS       DACAOP010000020        53054 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.020, whole genome shotgun sequence.
ACCESSION   DACAOP010000020 DACAOP010000000
VERSION     DACAOP010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 53054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53054
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.020"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..535
                     /locus_tag="IT892_001368"
     CDS             <1..535
                     /locus_tag="IT892_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HAP3134601.1"
                     /translation="FSNDSFSDSDTLAVVQAPGAQGARINYGNSTIDRWGYGVTSALS
                     PYHENRIALDINDLENDVELKSTSAVAVPRQGSVVFADFETVQGQSAIMNITRSDGKN
                     IPFAADIYDEQGNVIGNVGQGGQAFVRGIEQQGNISIKWLEQSKPVSCLAHYQQSPEA
                     EKIAQSIILNGIRCQIQ"
     gene            552..1121
                     /locus_tag="IT892_001369"
     CDS             552..1121
                     /locus_tag="IT892_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414680.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3134602.1"
                     /translation="MIKTTPHKIVILMGILLSPSVFATDINVEFTATVKATTCNITLT
                     GNNVTNDGNNNYTLRIPKMGLDKIANKTTESQADFKLVASGCSSGISWIDTTLTGNAS
                     SSSPKLIIPQSGDSSSTTSNIGMGFKKRTTDDATFLKPNSAEKIRWSTDEMQPDKGLE
                     MTVALRETDAGQGVPGNFRALATFNFIYQ"
     gene            1133..1738
                     /gene="yadL"
                     /locus_tag="IT892_001370"
     CDS             1133..1738
                     /gene="yadL"
                     /locus_tag="IT892_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein YadL"
                     /protein_id="HAP3134603.1"
                     /translation="MMTFKNLRYGLSSSVVLAASLFSVLSYAATDSIGLTVITTVEMG
                     TCTATLVNDSDQDISVVDFGDVYISEINAKTKVKTFKLKFKDCAGIPNKKAQIKLTKR
                     ATCEGTANDGAGFANGSTAADKASAVAVEVWSTVTPATGSATQFSCVTPASQEVTIST
                     AANAVVYYPMSARLVVEKNKTVNNVTAGKFSAPATFTVTYN"
     gene            1765..2361
                     /locus_tag="IT892_001371"
     CDS             1765..2361
                     /locus_tag="IT892_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3134604.1"
                     /translation="MHPTQRKLMKRIILFLSLLFCIACPAIAGQDIDLVANVKNSTCK
                     SGISNQGNIDLGVVGVGYFSGNVTPESYQPGGKEFTITVSDCALQGTGDVLNQLHIDF
                     RALSGVMAAGSRQIFANEISSGASNVGVVIFSTQDSANTFNVLNASGGSRSVYPVMSD
                     DMNGSSWKFSTRMQKIDPALSVTSGQLMSHVLVDIYYE"
     gene            2411..3649
                     /gene="yadC"
                     /locus_tag="IT892_001372"
     CDS             2411..3649
                     /gene="yadC"
                     /locus_tag="IT892_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial tip-adhesin YadC"
                     /protein_id="HAP3134605.1"
                     /translation="MKTIFRYILFLALYSCCNTVSAYTSFIVGNNAGVDNYRGPSTAA
                     QMTFNYTSTASNLVFYKPTQLGPTGVKMYWSYLDTGTGGGILYCNTSGRANPGPITIE
                     NAMVYSGKDYGGHKLFNTSVPGLYYTMLISRVWSAYDTITDIQSPGIYIGDPSNQEFF
                     FSVTDSDLQTKGCNKADDYDKFWAIGGIVHNITVEFYTDTNFDPTLNQQVQLSSSSNY
                     LYSFKAYSPGTKVVDHSNHIYVNFTLNNVKLTLPTCFTSILTGPSVNGSTVRMGEYSS
                     GTIKNGASPVPFDISLQNCIRVRNIETKLVTGKVGTQNTQLLGNTLTGSTAAKGVGVL
                     IEGLATSKNPLMTLKPNDTNSVYIDYETEDDTSDGVYPNQGNGTSQPLHFQATLKQDG
                     NIAIEPGEFKATSTFQVTYP"
     gene            3763..4557
                     /gene="panB"
                     /locus_tag="IT892_001373"
     CDS             3763..4557
                     /gene="panB"
                     /locus_tag="IT892_001373"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HAP3134606.1"
                     /translation="MKPTTISLLQKYKQEKKRFATITAYDYSFAKLFADEGLNVMLVG
                     DSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAG
                     DQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     gene            4569..5420
                     /gene="panC"
                     /locus_tag="IT892_001374"
     CDS             4569..5420
                     /gene="panC"
                     /locus_tag="IT892_001374"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HAP3134607.1"
                     /translation="MLIIETLPLLRQQILRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLID
                     NKMVELA"
     gene            complement(5494..6396)
                     /locus_tag="IT892_001375"
     CDS             complement(5494..6396)
                     /locus_tag="IT892_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HAP3134608.1"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLEIHLPVELRELCDLNTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGNPGYLHVVIEHQSKPDKKMAFRMMRYSIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNSPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
                     GHTEQADLFYGVLRDRETGGESMMTLAQWFEEKGIEKGIQQGRQEVSQEFAQRLLSKG
                     MSREDVAEMANLPLAEIDKVINLI"
     gene            6670..7050
                     /gene="panD"
                     /locus_tag="IT892_001376"
     CDS             6670..7050
                     /gene="panD"
                     /locus_tag="IT892_001376"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HAP3134609.1"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     gene            complement(7054..8283)
                     /locus_tag="IT892_001377"
     CDS             complement(7054..8283)
                     /locus_tag="IT892_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP3134610.1"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYAFNFGFGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLVTWKDTPVYNAPSAGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     ALDAQPDNGLSVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMVQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKW
                     NPKSLQFMSVSELNEIRDVFDFQSHTHFLHRVDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVWYLSYPFGGFNDNAVKAANDAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     gene            complement(8347..8787)
                     /locus_tag="IT892_001378"
     CDS             complement(8347..8787)
                     /locus_tag="IT892_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP3134611.1"
                     /translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHEADSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
                     CRETMTSSEFRERIVELGAPEVSSLWHQQQKNPPFVLKHNLYEY"
     gene            complement(8892..9662)
                     /locus_tag="IT892_001379"
     CDS             complement(8892..9662)
                     /locus_tag="IT892_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3134612.1"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     gene            complement(9659..10585)
                     /locus_tag="IT892_001380"
     CDS             complement(9659..10585)
                     /locus_tag="IT892_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP3134613.1"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRA"
     gene            10694..11356
                     /gene="can"
                     /locus_tag="IT892_001381"
     CDS             10694..11356
                     /gene="can"
                     /locus_tag="IT892_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HAP3134614.1"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHAN
                     HK"
     gene            complement(11397..11933)
                     /gene="hpt"
                     /locus_tag="IT892_001382"
     CDS             complement(11397..11933)
                     /gene="hpt"
                     /locus_tag="IT892_001382"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAP3134615.1"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
     gene            12139..14529
                     /locus_tag="IT892_001383"
     CDS             12139..14529
                     /locus_tag="IT892_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroloquinoline quinone-dependent
                     dehydrogenase"
                     /protein_id="HAP3134616.1"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQM
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
     gene            complement(14731..16281)
                     /gene="cueO"
                     /locus_tag="IT892_001384"
     CDS             complement(14731..16281)
                     /gene="cueO"
                     /locus_tag="IT892_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase CueO"
                     /protein_id="HAP3134617.1"
                     /translation="MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDA
                     RNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHW
                     HGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
                     VIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNG
                     AIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVL
                     MGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTL
                     SSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGN
                     MNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGT
                     QFRILSENGKPPAAHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDT
                     GMMLGFTV"
     gene            16447..16794
                     /locus_tag="IT892_001385"
     CDS             16447..16794
                     /locus_tag="IT892_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414664.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacC family pilotin-like protein"
                     /protein_id="HAP3134618.1"
                     /translation="MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKND
                     CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     gene            16900..17766
                     /gene="speE"
                     /locus_tag="IT892_001386"
     CDS             16900..17766
                     /gene="speE"
                     /locus_tag="IT892_001386"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HAP3134619.1"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALP
                     QYLQDALASQPS"
     gene            17782..18576
                     /gene="speD"
                     /locus_tag="IT892_001387"
     CDS             17782..18576
                     /gene="speD"
                     /locus_tag="IT892_001387"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HAP3134620.1"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     gene            complement(18614..18976)
                     /locus_tag="IT892_001388"
     CDS             complement(18614..18976)
                     /locus_tag="IT892_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414661.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacL family protein"
                     /protein_id="HAP3134621.1"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     gene            complement(19152..21749)
                     /gene="acnB"
                     /locus_tag="IT892_001389"
     CDS             complement(19152..21749)
                     /gene="acnB"
                     /locus_tag="IT892_001389"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HAP3134622.1"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFNQLSQYTEKA
                     DGVIFQTAV"
     gene            22104..23957
                     /locus_tag="IT892_001390"
     CDS             22104..23957
                     /locus_tag="IT892_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 domain-containing protein"
                     /protein_id="HAP3134623.1"
                     /translation="MKMTLPFKPHVLALICSAGLCAASTGLYIKSRTVEAPVEPQSTQ
                     LAVSDAAAVTFPATVSAPPVTPAVVKSAFSTAQIDQWVAPVALYPDALLSQVLMASTY
                     PTNVAQAVQWSHDNSLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKVITTTKKAVPVKQTVTAPVIPSN
                     TVLTANPVITEPATTVISIEPANPDVVYIPNYNPTVVYGNWANTAYPPVYLPPPAGEP
                     FVDSFVRGFGYSMGVVTTYALFSSIDWDDDDHDHHHHDNDDYHHHDGGHRDGNGWQHN
                     GDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVPYHDQDMAKRFHQTDVNGGMSA
                     TQLPAPTRDSQRQAAANQFQQRTHAAPVITRDTQRQAAAQRFNEAEHYGSYDDFHDFS
                     RRQLLTQQQKDAARQRYQSASPEQRQAVRERMQTNPKIQQRREAARERIQSASPEQRQ
                     AVREKMQTNPQNQQRRDAARERIQSASPEQRQVFKEKVQQRPLNQQQRDNARQRVQSA
                     SPEQRQVFREKVQESRPQRLNDSNHTVRLNNEQRSAVCERLSERGARRLER"
     gene            complement(24028..25452)
                     /gene="lpdA"
                     /locus_tag="IT892_001391"
     CDS             complement(24028..25452)
                     /gene="lpdA"
                     /locus_tag="IT892_001391"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAP3134624.1"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     gene            complement(25777..27669)
                     /gene="aceF"
                     /locus_tag="IT892_001392"
     CDS             complement(25777..27669)
                     /gene="aceF"
                     /locus_tag="IT892_001392"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex
                     dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAP3134625.1"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     gene            complement(27684..30347)
                     /gene="aceE"
                     /locus_tag="IT892_001393"
     CDS             complement(27684..30347)
                     /gene="aceE"
                     /locus_tag="IT892_001393"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HAP3134626.1"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     gene            complement(30508..31272)
                     /gene="pdhR"
                     /locus_tag="IT892_001394"
     CDS             complement(30508..31272)
                     /gene="pdhR"
                     /locus_tag="IT892_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR"
                     /protein_id="HAP3134627.1"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
     gene            31813..33186
                     /gene="aroP"
                     /locus_tag="IT892_001395"
     CDS             31813..33186
                     /gene="aroP"
                     /locus_tag="IT892_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter AroP"
                     /protein_id="HAP3134628.1"
                     /translation="MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSA
                     GPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVL
                     YVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIK
                     VIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLE
                     LVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIF
                     HELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPV
                     NTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQG
                     VVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKT
                     AKAVKAH"
     gene            complement(33229..34083)
                     /gene="ampE"
                     /locus_tag="IT892_001396"
     CDS             complement(33229..34083)
                     /gene="ampE"
                     /locus_tag="IT892_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase regulator AmpE"
                     /protein_id="HAP3134629.1"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     GMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     gene            complement(34080..34631)
                     /gene="ampD"
                     /locus_tag="IT892_001397"
     CDS             complement(34080..34631)
                     /gene="ampD"
                     /locus_tag="IT892_001397"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HAP3134630.1"
                     /translation="MLLEQGWLVGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDCYPDIAKNMTGHCDIAPD
                     RKTDPGPAFDWARFRVLVSKETT"
     gene            34719..35612
                     /gene="nadC"
                     /locus_tag="IT892_001398"
     CDS             34719..35612
                     /gene="nadC"
                     /locus_tag="IT892_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HAP3134631.1"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     SLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFR"
     gene            35815..36255
                     /gene="ppdD"
                     /locus_tag="IT892_001399"
     CDS             35815..36255
                     /gene="ppdD"
                     /locus_tag="IT892_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="HAP3134632.1"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN"
     gene            36265..37650
                     /gene="gspE"
                     /locus_tag="IT892_001400"
     CDS             36265..37650
                     /gene="gspE"
                     /locus_tag="IT892_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspE"
                     /protein_id="HAP3134633.1"
                     /translation="MNIPQLTALCLRYHGVLLDASEEVVHVAVVDAPSHELLDALHFA
                     TTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHI
                     EPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
                     AGNAVSFRIATLPCRGGEKVVLRLLQQVGQALDVNTLGMQPLQLADFAHALQQPQGLV
                     LVTGPTGSGKTVTLYSALQKLNTADINICSVEDPVEIPIAGLNQTQIHPRAGLTFQGV
                     LRALLRQDPDVIMIGEIRDGETAESAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVA
                     RWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPDNVWPSPLPHWQAPGCVHCYHGF
                     YGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEE
                     LIRVLGMPHGE"
     gene            37640..38842
                     /gene="hofC"
                     /locus_tag="IT892_001401"
     CDS             37640..38842
                     /gene="hofC"
                     /locus_tag="IT892_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein HofC"
                     /protein_id="HAP3134634.1"
                     /translation="MASKQLWRWHGITGDGNAQDGMLWAESRTLLLMALQQQMVTPLS
                     LKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
                     DLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWSW
                     LLVLFGFLLAIANKLLMRRPTWLIVRQKLLLRIPIMGSLMRGQKLTQIFTILALTQSA
                     GITFLQGVESVRETMRCPYWVQLLTQIQHDISNGQPIWLALKNTGEFSPLCLQLVRTG
                     EASGSLDLMLDNLAHHHRENTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     gene            complement(38877..39920)
                     /gene="guaC"
                     /locus_tag="IT892_001402"
     CDS             complement(38877..39920)
                     /gene="guaC"
                     /locus_tag="IT892_001402"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAP3134635.1"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNNL"
     gene            40145..40765
                     /gene="coaE"
                     /locus_tag="IT892_001403"
     CDS             40145..40765
                     /gene="coaE"
                     /locus_tag="IT892_001403"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAP3134636.1"
                     /translation="MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     gene            40765..41508
                     /gene="zapD"
                     /locus_tag="IT892_001404"
     CDS             40765..41508
                     /gene="zapD"
                     /locus_tag="IT892_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HAP3134637.1"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDTENGQVPERLDFELACC"
     gene            41518..41715
                     /gene="yacG"
                     /locus_tag="IT892_001405"
     CDS             41518..41715
                     /gene="yacG"
                     /locus_tag="IT892_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HAP3134638.1"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     gene            complement(41931..42320)
                     /gene="mutT"
                     /locus_tag="IT892_001406"
     CDS             complement(41931..42320)
                     /gene="mutT"
                     /locus_tag="IT892_001406"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HAP3134639.1"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVERWEGEPWGKEGQPG
                     EWMSLVGLNADDFPPANEPVIAKLKRL"
     gene            complement(42380..45085)
                     /gene="secA"
                     /locus_tag="IT892_001407"
     CDS             complement(42380..45085)
                     /gene="secA"
                     /locus_tag="IT892_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAP3134640.1"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     gene            complement(45147..45659)
                     /gene="secM"
                     /locus_tag="IT892_001408"
     CDS             complement(45147..45659)
                     /gene="secM"
                     /locus_tag="IT892_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secA regulator SecM"
                     /protein_id="HAP3134641.1"
                     /translation="MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPA
                     KATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTL
                     PVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQ
                     GIRAGPQRLT"
     gene            complement(45890..46807)
                     /gene="lpxC"
                     /locus_tag="IT892_001409"
     CDS             complement(45890..46807)
                     /gene="lpxC"
                     /locus_tag="IT892_001409"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HAP3134642.1"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     gene            complement(46908..48059)
                     /gene="ftsZ"
                     /locus_tag="IT892_001410"
     CDS             complement(46908..48059)
                     /gene="ftsZ"
                     /locus_tag="IT892_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAP3134643.1"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGIAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     gene            complement(48120..49382)
                     /gene="ftsA"
                     /locus_tag="IT892_001411"
     CDS             complement(48120..49382)
                     /gene="ftsA"
                     /locus_tag="IT892_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017374018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAP3134644.1"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     gene            complement(49379..50209)
                     /gene="ftsQ"
                     /locus_tag="IT892_001412"
     CDS             complement(49379..50209)
                     /gene="ftsQ"
                     /locus_tag="IT892_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HAP3134645.1"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPERTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     gene            complement(50211..51131)
                     /locus_tag="IT892_001413"
     CDS             complement(50211..51131)
                     /locus_tag="IT892_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase B"
                     /protein_id="HAP3134646.1"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     gene            complement(51124..52599)
                     /gene="murC"
                     /locus_tag="IT892_001414"
     CDS             complement(51124..52599)
                     /gene="murC"
                     /locus_tag="IT892_001414"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAP3134647.1"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPARVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     gene            complement(52653..>53054)
                     /gene="murG"
                     /locus_tag="IT892_001415"
     CDS             complement(52653..>53054)
                     /gene="murG"
                     /locus_tag="IT892_001415"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414632.1"
                     /note="N-acetylglucosaminyl transferase;
                     UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide)
                     pyrophosphoryl-undecaprenol N-acetylglucosamine
                     transferase; involved in cell wall formation; inner
                     membrane-associated; last step of peptidoglycan synthesis;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HAP3134648.1"
                     /translation="QQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTV
                     SEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRE
                     TLLTMAERARAASIPDATERVANEVSRVARA"
BASE COUNT        12919 a        14264 c        12949 g        12922 t
ORIGIN      
        1 tttcagtaat gatagtttta gcgactccga tacactggcg gtagttcaag ctccaggtgc
       61 tcaaggagcg cgaataaatt atggcaacag tactatcgat cgatggggtt atggtgtcac
      121 cagcgctctt tctccttatc atgaaaaccg tatcgcgctg gatatcaacg atcttgagaa
      181 cgatgttgaa ttaaaaagta ccagtgcagt agctgtaccg cgtcagggtt cagtcgtctt
      241 tgctgatttt gaaaccgtgc aagggcaatc agccattatg aacatcacac gaagtgatgg
      301 taaaaatatt ccatttgctg cagatattta tgatgagcaa ggcaatgtca ttggtaatgt
      361 tggacagggt ggacaagcat ttgttcgtgg tattgagcag cagggaaata tcagcattaa
      421 atggctcgaa caaagtaaac ccgtaagttg tcttgcgcat tatcaacaaa gcccagaagc
      481 agaaaaaata gcacaatcta ttattctgaa tggaattcgg tgtcagattc agtaactaca
      541 agggacgtca aatgataaaa acaacgccac ataaaatagt gatactgatg ggaatattat
      601 tatcaccctc agtatttgca acggatatta atgtagagtt tacagccact gtcaaagcga
      661 caacctgtaa catcacactt actggtaata acgtcacgaa tgatggcaat aataactaca
      721 cattgagaat ccctaagatg ggtctggata agatcgcgaa taaaacgaca gaatctcagg
      781 ctgattttaa actggttgcc agtgggtgca gcagtggcat cagttggatt gataccactc
      841 tgaccggaaa tgcatcatca agctcaccta agcttattat accgcagtct ggtgattcat
      901 cttcgacgac aagtaatatc ggtatgggtt tcaaaaaacg gactactgat gatgccactt
      961 tccttaaacc taacagtgcg gaaaagatac gctggagcac agacgagatg cagcccgata
     1021 agggtcttga aatgaccgtt gcgctacgtg aaacagatgc agggcaaggc gtaccgggga
     1081 attttcgtgc actggcgacg tttaatttca tctatcaata agaaggataa ttatgatgac
     1141 atttaaaaat ttacgttatg gattatccag cagtgtcgtt ttggctgcct cattgttcag
     1201 cgtactctct tatgcggcaa cagacagtat tggactgacc gttattacta ctgtagaaat
     1261 gggtacttgt accgctacat tagtaaatga ctctgatcag gacatttctg ttgttgattt
     1321 tggtgatgta tatatttctg aaatcaatgc caagaccaaa gtaaaaacat tcaaactcaa
     1381 attcaaagac tgtgcgggta tccccaataa aaaagcgcaa ataaaattaa ccaagcgagc
     1441 cacatgcgag ggaactgcta atgacggtgc ggggtttgca aatggttcca cagccgcaga
     1501 taaagcaagt gctgtcgccg ttgaagtctg gagcactgta actccggcaa cagggagtgc
     1561 aacacaattt agctgtgtaa caccagcatc acaagaggta acaatctcca ctgcagccaa
     1621 tgcggtcgtt tattatccga tgagtgcacg cctggtcgtg gaaaaaaata aaaccgtaaa
     1681 caatgtcact gcgggtaagt tttctgcacc agccacattt acagtaacct ataactaaca
     1741 gacttacaga ttcaggaact atatatgcat cccactcaac gtaagctgat gaagagaata
     1801 attctgtttc tgtcattact gttttgcatc gcctgtccag ccattgctgg acaggatatt
     1861 gaccttgttg ccaatgtaaa aaacagcacc tgcaaaagcg gaatcagtaa ccagggtaat
     1921 attgatcttg gcgtcgttgg ggtgggatat ttttcaggta atgttactcc tgaaagttat
     1981 caaccaggtg gaaaagagtt cactatcact gtatccgact gtgcattaca gggaactggc
     2041 gatgtgctaa atcagttaca tattgatttt agagccctta gcggtgtcat ggctgctggc
     2101 tctaggcaaa tatttgctaa tgaaatttcg tcaggagcaa gtaatgtagg agtagttata
     2161 ttttctactc aggattcggc gaatacattc aatgttctta atgcttcagg cggatctcgt
     2221 tccgtttatc cagtaatgtc ggatgacatg aatggttcat cctggaaatt tagcacccga
     2281 atgcaaaaaa tcgatcctgc attgagtgtt acatctggtc aacttatgag ccatgtgtta
     2341 gtggatattt actacgaata acaaacaaaa acagcgcaaa ccataacaat aaagaaacat
     2401 tggagtaaaa atgaagacta tcttcaggta cattcttttt ttagcactgt attcttgttg
     2461 taatacagtc agtgcatata caagttttat tgtgggaaat aatgcaggag ttgataacta
     2521 tcgaggcccc tccactgccg cacagatgac ctttaattac acatcaacag caagcaactt
     2581 ggttttttat aaacccacgc agctcggccc gactggggta aaaatgtact ggtcatacct
     2641 ggatacaggt accggtggtg gtattcttta ctgcaataca tctggcagag cgaatcctgg
     2701 tccaataact attgaaaatg ccatggtcta ttcaggtaaa gattatggcg gacataaact
     2761 atttaataca tctgttcctg gtctgtatta caccatgtta atatcaaggg tctggtctgc
     2821 atacgataca ataactgaca ttcaatcgcc aggaatctat atcggagatc cttccaacca
     2881 agaatttttc ttttccgtca cagacagcga tctacaaact aagggttgca acaaagcaga
     2941 cgactacgat aagttttggg ctattggtgg tatagtacac aacataactg ttgaatttta
     3001 tacagatact aatttcgatc ctacacttaa tcagcaagtc cagttatcca gttcatcaaa
     3061 ttacctttat tcgtttaagg cctacagtcc tggtacaaaa gttgtagatc acagcaacca
     3121 catttatgtc aatttcacac tgaataatgt caaattaacc ttaccaacat gttttacctc
     3181 catacttacc gggccatcag tcaatggttc aacggttaga atgggagaat atagctctgg
     3241 gacaattaaa aatggcgctt cacctgttcc ctttgatatc tcgcttcaga attgtattcg
     3301 tgtgcgtaat attgaaacaa aactcgtcac tggaaaagta ggtactcaaa acacacaact
     3361 gcttggtaat acgcttactg gaagcactgc cgccaaaggc gttggcgtac tcattgaagg
     3421 tttagcaacc agtaaaaatc cgctaatgac attaaaacct aatgatacga attctgttta
     3481 tatagattat gaaaccgaag atgacacctc cgatggggtt taccctaatc aaggtaacgg
     3541 cacatcacag cctcttcatt tccaggcaac attaaagcaa gacgggaata ttgctatcga
     3601 acccggcgaa tttaaagcca ccagtacttt ccaggtaacc tatccctgat aacgtagcag
     3661 cactgtcacc ttctggcagt gctgctacgg ataaatcatt gcccccacca atgtgactga
     3721 taaaatgcca gacagcacaa catcaattta tcaggatacg ttatgaaacc gaccaccatc
     3781 tccttactgc agaagtacaa acaggaaaaa aaacgtttcg cgaccatcac cgcttatgac
     3841 tatagcttcg ccaaactctt tgctgatgaa gggcttaacg tcatgctggt gggcgattcg
     3901 ctgggcatga cggttcaggg gcacgactcc accctgccag ttaccgttgc cgatatcgcc
     3961 taccacactg ccgccgtacg tcgcggcgca ccaaactgcc tgctgctggc tgacctgccg
     4021 tttatggcgt atgccacgcc ggaacaagcc ttcgaaaacg ccgcaacggt tatgcgtgcc
     4081 ggtgctaaca tggtcaaaat tgaaggcggt gagtggctgg tagaaaccgt acaaatgctg
     4141 accgaacgtg ccgttcctgt atgtggtcac ttaggtttaa caccacagtc agtgaatatt
     4201 ttcggtggct acaaagttca ggggcgcggc gatgaagcgg gcgatcaact gctcagcgat
     4261 gcattagcct tagaagctgc tggggcacag ctgctggtgc tggaatgcgt gccggttgaa
     4321 ctggcaaaac gtattaccga agcactggcg atcccggtta ttggcattgg cgcaggcaac
     4381 gtcactgacg ggcagatcct cgtgatgcac gacgcctttg gtattaccgg cggtcacatt
     4441 cctaaattcg ctaaaaattt cctcgccgaa acgggcgaca tccgcgcggc tgtgcggcag
     4501 tatatggctg aagtggagtc cggcgtttat ccgggcgaag aacacagttt ccattaagga
     4561 gtcacgttgt gttaattatc gaaaccctgc cgctgctgcg tcagcaaatt ctccgcctgc
     4621 gtatggaagg caagcgcgtg gcgctggtgc ctaccatggg taacctgcac gatggccata
     4681 tgaagctggt cgacgaagcc aaagcccgcg ccgatgtggt cgtcgtcagt attttcgtta
     4741 acccgatgca gttcgaccgc ccggaagatc tggctcgtta tccacggacc ttgcaggagg
     4801 actgcgagaa gctaaacaaa cgtaaagtgg atttagtttt cgccccttcg gtaaaagaga
     4861 tctacccgaa cggtactgaa acccacactt acgttgacgt tcctggcctt tcgaccatgc
     4921 tggaaggtgc cagccgtccg ggacattttc gcggcgtttc gactattgtc agcaagctgt
     4981 tcaacctggt ccagccggac atcgcctgct tcggtgaaaa agattttcag caactggcgc
     5041 tgatccgcaa aatggttgcc gatatgggct tcgatattga gattgtcggt gtgccaatta
     5101 tgcgcgccaa agacggtctg gcgctaagtt cccgtaacgg ttatctgacg gcggaacaac
     5161 gcaaaattgc gcctggtctg tacaaagttt taagttcgat tgctgacaaa ttgcaggctg
     5221 gggaacggga tctcgatgaa attattacca ttgcggggca agaactgaat gaaaaaggct
     5281 tccgcgccga tgatattcag attcgcgatg ccgacacatt gctggaagtt tctgaaacca
     5341 gcaaacgggc agtaattctg gtagccgcct ggcttggcga tgctcgcctg atcgacaaca
     5401 aaatggtcga gctggcgtaa tacttaactg gcgctacggc tgatggcgcc agttattaat
     5461 ttaccccacg tcatctgtca taacacaggt aacttaaata aggttaatta ccttatcaat
     5521 ctcagcaaga ggtaaatttg ccatctctgc aacgtcttcc cgagacattc ctttactcag
     5581 aagacgctgg gcgaattcct gacttacttc ctgtcttccc tgctgaatcc ccttctcaat
     5641 ccctttctct tcaaaccact gcgccagcgt catcatagac tcccctcccg tttccctgtc
     5701 tctcaacaca ccgtaaaaca aatccgcttg ttcagtatga ccgcgttgca gcatatagtt
     5761 ttgcatggca actaactgac ttccgctagt gtacccttcg tcgatcagcg tgaccagttg
     5821 ctcaagcaat aacattaagt cgcgctggcg aatatgtttt tgcagtagtt cgagaatcgc
     5881 aatccgccga tgttgcatga tttcgtcatc cggtgtgatg gtgatatcca ccagcgggaa
     5941 aggactgtta tagacgcgtc gcgccagctc cggcgagtaa aacatatcaa accagcacat
     6001 tgatagcgga taaggtgtgg cctcgccctg ataaaacagt atcggcacca ccagcggcag
     6061 cttatcgtgg tcagcctcca gatgccggtg catggcggct atagaataac gcatcatgcg
     6121 aaaggccatt ttcttatccg gcttgctttg gtgttcaatc acaacatgca gataaccggg
     6181 attgccctgc atttgcacgg aatagagcac gtccgtgctg tgtcctttca ggctctcttc
     6241 aatgaaactc cccgactcta aatgaagcgt gttgaggtca caaagttcgc gtaattccac
     6301 tggcaaatgt atctccagaa agtcgcgagc cgtctccgca tgcattaaaa attgtttaaa
     6361 taccgcgtca tgcggtgtgg tactcggtgc atccatcttc cctgtcttcc gtgtggcttt
     6421 gcgtgaaggc agtatccagt caaggcgcgc tatcgtcagc cacctcttta ttgtttaccg
     6481 agcagcgttc agagaaatat caattcgtta caggcgatac atggcacgct tcggcgcggt
     6541 acgcaaactg ctgacgcaaa tgccgtcaga tgagtagaca ctaaacaaaa atcgggcaat
     6601 actgcgtgag aatttcctca aagcaggcat cgcctgcttc gttaacgaca gggtagaaag
     6661 gtagaagtta tgattcgcac gatgctgcag ggcaaactcc accgcgtgaa agtgactcat
     6721 gcggacctgc actatgaagg ttcttgcgcc attgaccagg attttcttga cgcagccggt
     6781 attctcgaaa acgaagccat tgatatctgg aatgtcacca acggcaagcg tttctccact
     6841 tatgccatcg cggcagaacg cggttcgaga attatttctg ttaacggtgc ggcggcccac
     6901 tgcgccagtg tcggcgatat tgtcatcatc gccagcttcg ttaccatgcc agatgaagaa
     6961 gctcgcacct ggcgacccaa cgtcgcctat tttgaaggcg acaatgaaat gaaacgtacc
     7021 gcgaaagcga ttccggtaca ggttgcttga ttgttatccc tgcggctggt tactcaccag
     7081 ccgcgacatc gtctccagcg aatccgttct taagatataa agtcgtttta gtaacaacgg
     7141 attatccccc ggttttactt tgcctttcat ggttgtcacc gccaggtgaa atccggcatc
     7201 gtttgctgcc ttcacggcgt tgtcattaaa tccgccaaac ggatacgaaa gataccagac
     7261 atgcggatta aattgcgcca gagcgcggcg tgaacgtgca aaatcaaaca gaatattgtg
     7321 ctcactacgg ctcagtaata tgggtcggcg ataaccatct acccgatgca aaaaatgggt
     7381 atgtgactgg aaatcaaata catcgcgaat ttcgttaagc tcagaaacgc tcataaattg
     7441 cagcgatttt gggttccact tctgcgggtg acgtttgatg cgtgaggtaa caataaacgc
     7501 cgtcgccttc atgccatatt gtttcaacac aggatacgca tagcggctca ccgacttgag
     7561 gccatcatca aaggtaatca ccaccgctcg cgcagggaga ttgatcttat tcttcacgta
     7621 gccttccagc tgcaccatgc tcagtgtcgc gtatcccctg tcacgcagcc aggccatctg
     7681 gttattgaaa gcgcgtaccg atgtggtcgt cgaagtatgg cgaaaacggg tgttttcttc
     7741 gtcgcgcaga atatggtgat aggttagcac cgacaggcca ttatcgggtt gggcatccag
     7801 tgcgctgata taggccagtc gatcgccaat acggatctga taccaggttt gatttaacct
     7861 gtctttcagt ttatgcaaaa tcgggtagcg caaattgtcc gccagtaccc caaatggcgc
     7921 acttcccgca ctcggcgcgt tatagaccgg cgtatctttc caggtaacta agttctgatt
     7981 actcagcggc ttgttgaggt cgcccaaacc gtcttcaact ttttgtcgcc cctgaaccgg
     8041 ctcgagatga cctttatcga taaaaccttt gccaaagcca aaattaaatg cgtaataact
     8101 tgcggcagtg ggctccacgg caatgatttg tccggcccga atattcccca cggtcaccat
     8161 cttgtcacca atttgcgccc agaccgcagc attttcgatg gtttgcatat aacgggcagg
     8221 taacgcggca ctgacacttg cggtaaacag catcagcagg agaataacag cttgtttgta
     8281 catgaaaaaa taaccgaggg tgaaacaacg cttttattgt agcaaaagcg ccatcagaat
     8341 cgcgggttaa tactcataca aattatgttt gaggacgaaa ggcggatttt tttgttgttg
     8401 gtgccaaaga ctactcacct ccggcgcacc cagttcgaca atacgctcgc gaaactctga
     8461 actggtcatg gtttcacggc aagccatcat ctgttcaatt aacggtaacg tgacaccaga
     8521 aatcacttcg caacgggagt gtttgtggct taataatgaa gccacgcgat acggtggcgc
     8581 tccggctata tcggttaaga agatgacacc ctcaccagag tccgcttcat gcagagcatc
     8641 gcacatcatg cggctgagca tattagagct taatccgcgc cagaaattca cggcccggca
     8701 ctgaagaagt gccccatgtt ttttctccag cgcatccagt atctcttgcg cccggtcatc
     8761 gtgacaggta attacccaac ctaacatcgc cttcctcctt agccgaaaat cagtctaccc
     8821 tgaccattgt tgataaaggg tgatagccgt caaaactcct ctcccccaaa tccagaggag
     8881 aggaaatagc cttagctacg caaaccacgt ccacgttgga tcagcgacca acagatcaaa
     8941 taaaacgcca caataaagac caccagtacg ccaaaggtag tgaccagcgg aacatcattg
     9001 ataccgagga agccgtagcg gaaaccactg atcatataaa cgattgggtt caggtgcgac
     9061 agcccttgcc agaacggcgg caacaaagtc agtgagtaaa agaccccgcc caaatacgtg
     9121 agtggcgtta acacaaaggt tggcaccagg ctgatgtcat cgaacgtttt ggcaaacaca
     9181 ccgttcagca aacccgcaag ggagaacaac accgccgtga gcaccagcgt taaggcaacg
     9241 aatacccacg aatgcacctg aaatggcaca aaaaacagtg aaattgccgt caccagaatg
     9301 ccaacaaaca gaccacgcgc cacgccaccg ccgacatatc cggcaataat gacgtgagtc
     9361 ggaaccggcg ctaccagcag ctcttcaata ttacgctgga acttggcacc aaaaaatgat
     9421 gacgcaacgt tggcgtaggc attggtgatc accgacatca tgatcagccc cggtacgatg
     9481 aactgcatat agctgaagcc atgcatatcg ccaatacgcg aaccaatcag gttaccgaag
     9541 ataataaagt aaagggtcat ggtgatgact ggcggcacca gcgtctgcac ccagatacgc
     9601 ataaagcgat ggatctcttt cgcccagatg ctttttagcg ccacccagta aagatgcatc
     9661 atgcgcgatc tccttgtttt tcattaacca gtgaaacaaa cagctcttcc agacggttag
     9721 ctttgttacg catacttaat acctgaatgc cctgctcact taactgcgta aatacgctgt
     9781 tgatcccctg ctcacgcagc acttcaactt ccagcgtcgc ggtatcgacc agtcgatact
     9841 gatagccatc gagcttcggt aacgggcttt tcggtgcgag atcgagaata aaggtttccg
     9901 atttcagctt cgccagcagc gccttcatcg aggtattttc caccagctca ccgtgttgaa
     9961 taatgccgat attgcggcac agcatttctg cttcttccag gtagtgtgtg gtgagaatga
    10021 tggtggtgcc tttgtcgttt aaatccttca aaaagcccca cattgagcgg cgaagttcaa
    10081 tatccacgcc tgcggtcggt tcgtcgagaa tcagtagttt aggttcatgc attaacgcac
    10141 gggcaatcat taaacggcgc ttcatcccgc cagataacat acgcgcacgt tcgttgcgtt
    10201 ttccccatag atcgagttgt ttaagatact tttcgctgcg gatgtacgct tctttgcgct
    10261 ccacgccgta gtaccctgcc tgattcacca caatttgctg cacggtttca aacgggttga
    10321 agttaaattc ctgcggcacc agtcccaact gacgtttagc gttcacgaca tccttctcga
    10381 gatcgtaacc aaatacgctg acccgcccgg aggttttatt taccagagag ctgataatac
    10441 cgatagtggt cgatttcccg gccccgttcg gcccgagaag cgcataaaaa tcacccgctt
    10501 cgacctgcaa atctatccca cgaagcgcct gaacgccgcc tggataggtt tttttaagct
    10561 gttgaagttc cagtgcaatg gtcataaatt tttacttacc ttacgttctt acactttatc
    10621 tgtggtttaa atcgtcccgg agttgcccta tattagccaa acgtaattat ttggttacag
    10681 gtcgttaacc tccatgaaag acatagatac actcatcagc aacaatgcac tatggtcaaa
    10741 aatgctggtg gaagaggatc ccgggttttt tgagaaactg gcacaagcgc aaaaaccgcg
    10801 ctttctatgg attggatgtt ccgacagtcg cgttcctgca gaacgtttaa ccggtcttga
    10861 gccgggcgaa ctctttgttc accgtaatgt tgctaacctg gtcattcaca ctgacctgaa
    10921 ctgcctttcc gtggttcagt atgcagtgga tgtactcgaa gttgaacaca ttattatctg
    10981 tggccactac ggttgcggcg gcgtacaagc cgcagttgaa aacccggaac tggggcttat
    11041 caacaactgg ctgctgcata tccgcgatat ctggttcaaa catagctcat tgctcggcga
    11101 aatgccgcaa gagcgccgtc tggatacctt gtgtgaactg aacgtcatgg aacaggtgta
    11161 taacctgggc cactccacca ttatgcaatc agcgtggaaa cgcgggcaga aagttaccat
    11221 tcacggctgg gcctacggca ttcacgacgg cttgctgcgt gatctggatg ttaccgccac
    11281 caaccgcgaa acccttgagc aacgttaccg tcacgggatt tccaacctca agctgaaaca
    11341 cgccaaccac aaataaaaat gccatgccgg atgcaacaca tccggcaact tcacacttac
    11401 tcgtccagca gaatcacttt gccgatatac ggcagatgac ggtaacgctg tgcgtaatca
    11461 atgccgtaac ccaccacaaa ctcatccggg atcgagaaac cgataaattc taccgggacg
    11521 ttcacttcac gacgggacgg tttatccagc agcgtacaaa tcgccagcga cttcggttcg
    11581 cgcaggctta agatctcacg cactttcgac agtgtattcc ccgagtcgat gatatcttca
    11641 acaatcagca cgtccttgcc acggatatct tcatccagat ctttgaggat tttcacatca
    11701 cgggtggtgg acatgccgct accgtagctg gaggcggtca taaagtcgac ttcatgagat
    11761 acctgaactt cacggcacag gtccgccata aacataaatg agccacgcag cagacccacc
    11821 agcaccatat cgctgccgct gtctttgtaa cgctcagtaa tctgacgacc cagttcggcg
    11881 atacgcgctt taatctccgc ttcggggatc attacttcta cagtatgttt catatctcta
    11941 accatatgat ttaaaaacaa atcacttcgc acgggcaggt tttggcaccg caacaaagcg
    12001 caagacacgc agtataccag taaaactatt cattcgcgga atctgttaat aaagctcgaa
    12061 ttgtgatgac gatcacacat gttaaaacct ataattaatt gctactaaaa tattaatgaa
    12121 ttgaaatggt gtctatttat ggcaattaac aatacaggct cgcgacgatt actcgtcacg
    12181 ctaacagccc tttttgcagc gctttgcggg ctgtatctac tcattggcgg aggctggctg
    12241 gtcgcgattg gcggctcctg gtactaccct atcgctggcc ttgtgatgct cggcgtcgcc
    12301 tggatgctgt ggcgcagtaa acgcgccgcg ctttggctat acgcagccct gctgctcggc
    12361 accatgattt ggggcgtctg ggaagttggt ttcgacttct gggcgctgac tccgcgcagc
    12421 gacattctgg tcttcttcgg catctggctg atcctgccgt ttgtctggcg tcgcctggtc
    12481 attcctgcca gcggcgcagt tgccgcactg gtggtcgcac tgctgattag cggtggtatc
    12541 ctgacctggg ccggatttaa cgatccgcag gagatcaacg gcaccttaag cgccgatgcc
    12601 acacctgctg aagctatctc ccccgtagcc gatcaggact ggcctgccta tggtcgtaat
    12661 caggaaggtc aacgcttttc gccgctgaaa caaattaacg ccgataacgt ccataatctg
    12721 aaagaagcct gggtgttccg tactggcgat gtgaagcagc cgaacgatcc gggtgaaatc
    12781 accaatgaag tgacgccgat taaagtgggc gacacccttt acctgtgtac cgctcaccag
    12841 cgcctgtttg cgcttgatgc cgccagcggc aaagagaaat ggcattacga tcctgagctg
    12901 aaaaccaacg agtctttcca gcacgtaacc tgccgtggtg tctcttatca tgaagccaaa
    12961 gcagaaaccg cttcgccgga agtgatggcg gattgcccgc gtcgtatcat tcttccggtc
    13021 aatgatggtc gactgattgc gattaacgct gaaaacggca aactgtgcga aaccttcgcc
    13081 aataaaggcg tgctcaatct gcaaagcaat atgccagaca ccaaaccggg tctgtatgaa
    13141 ccgacttcgc caccgattat caccgataaa accatcgtga tggccggttc agttaccgat
    13201 aacttctcaa cccgcgaaac gtctggcgtg atccgtggtt ttgatgtcaa caccggggag
    13261 ctgctgtggg cttttgatcc cggcgcgaaa gatccgaacg caatcccgtc tgacgaacac
    13321 acctttacct ttaactcgcc aaactcctgg gcaccagcgg cctatgacgc gaagctggat
    13381 ctggtctatc tgccgatggg cgtgaccacg ccggatatct ggggcggtaa ccgcacaccg
    13441 gaacaggaac gttatgccag ctcgattctg gcgctgaatg ccactaccgg gaaactggcg
    13501 tggagctacc agaccgttca ccacgacctg tgggacatgg atcttccggc acagccgacg
    13561 ctggcggaca tcaccgttaa tggtcagaaa gtgccagtta tttacgctcc ggcgaaaacc
    13621 ggcaacattt ttgtgctcga tcgtcgtaat ggcgaactgg tggttccggc accggaaaaa
    13681 ccggttcccc aaggtgcagc gaaaggcgat tacgtaaccc caactcaacc gttttctgaa
    13741 ctgagcttcc gtccgacgaa agatttgagc ggtgcggata tgtggggagc caccatgttt
    13801 gaccaactgg tgtgccgcgt gatgttccac cagatgcgct atgaaggcat tttcaccccg
    13861 ccatctgaac agggtacgct ggtcttcccg ggtaacctgg ggatgttcga atggggcggg
    13921 atttccgttg atccaaatcg tgaagtggcg attgccaacc caatggcact gccgtttgtt
    13981 tcgaaactga tcccgcgtgg tcctggcaac ccgatggagc agccgaaaga tgccaaaggc
    14041 acgggtacgg aatccggcat tcagccacag tacggtgtac cgtatggtgt cacgctcaac
    14101 ccgttcctct caccatttgg tctgccatgt aaacagccag catggggtta tatctcggcg
    14161 ctggatctga aaactaatga agtggtgtgg aagaaacgta ttggtacgcc gcaggacagt
    14221 atgccgttcc cgatgccggt tccggtgccg ttcaatatgg gtatgccgat gctgggcggg
    14281 ccaatctcca cggcgggtaa cgtgctgttt atcgccgcta cggcagataa ctacctgcgc
    14341 gcttacaaca tgagcaacgg tgaaaaactg tggcagggtc gtttaccagc gggtggtcag
    14401 gctacgccaa tgacctatga agtgaatggt aagcagtatg tggtgatctc cgcaggcggt
    14461 cacggttcat ttggtacgaa gatgggcgac tatattgtgg cttatgcgct gccggatgat
    14521 gtgaagtaag acttgctcag attgctgaca acgtgcgcgt tgttcatgcc ggatgcggcg
    14581 tgaacgcctt atccagccta caaaattgtg caaaatcaat ggattgcaca gctagcgtag
    14641 gcctgataag cgtagcgcat caggcagatt tgcgtttgtc atcagtttaa tgcccggaga
    14701 gatccgggca tatttccgaa tacggtcttt ttataccgta aaccctaaca tcatccccgt
    14761 atcttcatgc tccagcagat ggcagtgcgc catataagca tgttctttcg gtgcatcgtg
    14821 attaaacttc accagcactt cgctgacatt accttctacc ttaacggtat ctttccagcc
    14881 cgcgcgatga gccgctggcg gtttgccatt ttctgacaag atacggaact gcgtgccgtg
    14941 gatatggaac ggatgcagca tcatgtcgcc cacgccagag ataacccaac gttcgtattg
    15001 ccctttcgcc gccgcaaaca tcggcttgtt catatcaaac gcctgaccgt tgattttgtt
    15061 ggcatggtgg aaatcgaact tcccgccgtg gttcatatga ttcatattgc cgtgccccat
    15121 atggcccatc atctggctgt gatccatccc ggccatcgcc tgatcgccat atttctccat
    15181 tagcatctgc atccccatca tatcgagcat cgggtccata gagagttgca gcttgcgtac
    15241 cgtcagccct tccagcgaag gtaacgcagg caggctactt aatgtgtctg gcaaagcacc
    15301 ggaggcacta atagcaatcg gctgaatccg cattaccgga tgaggcttat caaacggcgc
    15361 aatcgccatc cccatctggc tgaccggcag cgtcaccagg tcaaagggtt tgttatcgtt
    15421 aacctccacc agcacttcaa aacgctcgcc catcagcacc ggcagttcgc tcaccttcac
    15481 tggttcaggt agcagaccac cgtcgctggc aatcacatac agcgggcgat tgtcgctggt
    15541 ggcgaaattg agcgaacggg cattacagcc attgagcaaa cgcaggcgca gccaaccacg
    15601 cggggcagcg tgttgcgggt agattgcacc gttggtcagc aacgtatcgc caaaccagcc
    15661 cacggcggcg gtcatcacat ccagttgata atcaatctgc ccgtcggcgc taaatttctt
    15721 atcctgaacg atcaccggaa catcatcgat accccactgt tttggcagca ttaatttcag
    15781 gatctcgtca tcttcaatca ccaccagccc agccagcccc atcgccacct gtcgcccggt
    15841 tttgccgtgc tgatgcggat ggaaccagca ggtagcggca ggttgatcaa cgttcaacgt
    15901 caccgagcgc ttgccacctg gcggaataat tccctgcggg ccgccgtcga cttcacccgg
    15961 tacttccagc ccgtgccagt gcaacgttgt ctcttccgtc agttggttgt agatatcaac
    16021 cgttaccgct ttgccgcgct gtaatttcac cgccggcccc agcagattgc cgttatagcc
    16081 ccaggtagtt gcagttttcc cgccaaaggt ggactggcct gcgccaatag ttaactgaat
    16141 gcgattacgg gcatcggtcg tgagcaaatc agggatcggt aacgttgggc gttctgccgc
    16201 aaatactgcg cggctccaca gcggcaaagc cgaagccaca cccagcgcga cggaatattt
    16261 taagaaatca cgacgttgca tagttatttc cttattctta agcaggcgaa acaaaatcaa
    16321 acgttgagca tagtccttcc ccttacggga aggtcaagcc gcagacacaa tttaatcgac
    16381 aataatggtc gtcgcctcgc tcgcagtgtg ctaacgttta tcttctttaa gcccctggta
    16441 gaagcaatga agacgttttt cagaacagtg ttattcggca gcctgatggc cgtctgcgca
    16501 aacagttacg cgctcagcga gtctgaagcc gaagatatgg ccgatttaac ggcagttttt
    16561 gtctttctga agaacgattg tggttaccag aacttaccta acgggcaaat tcgtcgcgca
    16621 ctggtctttt tcgctcagca aaaccagtgg gacctcagta attacgacac cttcgacatg
    16681 aaagccctcg gtgaagacag ctaccgcgat ctcagcggca ttggcattcc cgtcgctaaa
    16741 aaatgcaaag ccctggcccg cgattcctta agcctgcttg cctacgtcaa ataatccctg
    16801 ataccttttt gtagaaatat tgaccgtgca tccgcggtca atgttagcta ttatgttgcg
    16861 cccttttttt acgggtgtta acaaaggagg tatcaaccca tggccgaaaa aaaacagtgg
    16921 catgaaacgc tacacgacca gtttgggcag tactttgcgg tagataacgt tctgtatcat
    16981 gaaaagaccg atcaccagga tctgatcatt tttgagaacg ctgcatttgg tcgcgtaatg
    17041 gcgctggatg gcgtagtaca aaccaccgag cgcgacgagt ttatctatca tgagatgatg
    17101 acccatgttc cgctactggc ccatggtcac gcgaaacatg tgctgattat cggcggcggc
    17161 gacggtgcca tgctgcgtga agtaacccga cataaaaacg ttgagtcaat cacgatggtg
    17221 gaaatcgatg cgggtgtcgt atcgttctgc cgtcagtatc tacccaacca taacgccggt
    17281 agctacgacg atccgcgctt taagctggtg atcgacgatg gcgtcaattt cgttaatcaa
    17341 accagccaga cctttgatgt cattatctcc gactgcaccg atcctatcgg tcccggcgaa
    17401 agccttttca cttcggcatt ttatgaaggc tgcaaacgtt gcctgaatcc tggcggtatc
    17461 ttcgtcgcac aaaacggcgt ctgcttttta cagcaggaag aagccatcga cagccatcgc
    17521 aaactcagcc attacttcag cgacgttggc ttttatcagg cggcgatccc gacctattac
    17581 ggcggtatca tgacttttgc atgggcgaca gataacgacg ccttacgcca tctctcaacc
    17641 gaaattattc aggcgcgttt tctcgcctct ggcctgaaat gccgttatta caatccggca
    17701 atccatacgg cagcttttgc cttacctcag tatctgcaag acgcactggc ttcacagccg
    17761 tcctaaggag aagataagaa attgaaaaaa ctgaaactgc atggctttaa taatctgacc
    17821 aaaagtctga gtttttgtat ttacgatatc tgctacgcca aaactgccga agagcgcgac
    17881 ggttatattg cttatatcga tgaactctat aatgccaacc gtctgaccga aatcctgtca
    17941 gaaacctgtt ccattatcgg ggctaatatt cttaacatcg cccgccagga ttacgaacca
    18001 cagggtgcca gcgtcactat tctggtgagt gaagaaccgg ttgacccgaa actcatcgac
    18061 aaaacagaac accccggccc actgccagaa acggtcgttg cccatcttga taaaagtcat
    18121 atttgcgtac atacctaccc ggaaagtcat cctgaaggcg gtttatgtac cttccgcgcc
    18181 gatattgaag tctctacctg cggcgtgatt tctccgctga aggcgctgaa ttacctgatc
    18241 caccagcttg agtccgatat cgtaaccatt gattatcgcg tgcgcggttt tacccgcgac
    18301 attaacggta tgaagcactt tatcgaccat gagattaatt cgattcagaa ctttatgtct
    18361 gacgatatga aggcgctgta tgacatggtg gatgtgaacg tctatcagga aaatatcttc
    18421 cataccaaga tgttgcttaa agagttcgac cttaagcact acatgttcca caccaaaccg
    18481 gaagacttaa ccgacagcga gcgccaggaa attaccgctg cgctgtggaa agaaatgcgc
    18541 gagatttatt acgggcgcaa tatgccagct gtttaacggc tctggcggag ctcccaggct
    18601 ccgccagatt tatttacttc tgctgcacga aattgcggta agccgccacg acctgcagaa
    18661 aatcctcaac gccgcatagc gacaggcttt cttcgtcgta gtagttcatc ccctcttcca
    18721 tttcatcgcc agcgaattcc agttgattgg cgcgaaccat cacctcttca ccgtccatcc
    18781 acagggtgta ttcatgccct gcccgttgcc aggaccgttc gctacctttc agtgcgtgcg
    18841 ctgcttgttc cacttcatca agcaaggcca ggttttcttt cacctcttca ttaaaccagt
    18901 gcccgaccac ttcatgcccc atggacatac gcacctttac cactccggta atatcgcgca
    18961 gaaattcgta atccatagtg tgttcctctg ctcccggcaa tgcaccgaaa tcgcattgcg
    19021 ccattgatgt aattatcgca gccttaccgg agaaaaacag cggaacggcg atggtttaga
    19081 aataaaaaaa tgcccgggaa tctcattcac cgggcattgt gtcgtttatg cgcagcgcgt
    19141 gcgctgactt tttaaaccgc agtctggaaa atcaccccat cggctttctc ggtgtactga
    19201 gaaagctggt tgaagttcag ataacggtaa gtatcaacgg ctgttttatc tacctgcgcc
    19261 acgtaggtct ggtactcttc cggcgtcggc agtttgccaa tcagcgccgc aacagccgcc
    19321 agttccgcag aagccaggaa gacattcgcg ccagtaccca gacggttcgg gaagttacgg
    19381 gtagaggtgg aaaccaccgt tgcaccgtcc gccacacgcg cctggttacc catacacagg
    19441 gaacagccag ggatctcgat acgcgcacca ctcttaccga agacgctgta gtagccttct
    19501 tcggtcaact gtgcggcgtc catacgggtt ggcggtgcca cccacaggcg ggtcggcaac
    19561 tgacctttat gcgcatccag cagtttaccc gcagcacgga agtgaccgat gttggtcatg
    19621 caggaaccga taaacacttc gtcgatcttc tcaccctgta ccgcagacag cggacgcgcg
    19681 tcatccgggt cgttcggagc acacaggatt ggctctttaa tatccgccag atcgatgtcg
    19741 atcactgccg cgtattccgc atctgcatcg gcttccagca gctcaggatt cgccagccat
    19801 ttttccatgc cctgaatacg acgttccagg gtacgacgat cgccgtaacc ttccgcgatc
    19861 atccacttca gcaggacgat gttagagttc aggtattcga tgatcggttc tttgttcagc
    19921 ttgatggtac aaccagcggc agaacgctcg gcggacgcat cggttagctc aaaggcctgc
    19981 tcaactttca gatccggcag accttcaatt tccaggatgc ggccagagaa gatgtttttc
    20041 ttgcctttct tctcaacggt cagcagacct tgtttgatcg catacagcgg aatagcgtgt
    20101 accagatcgc gcagggtgat gcccggctgc attttgcctt tgaagcgcac cagaacggat
    20161 tccggcatat caagcggcat tacgccagtt gcggcagcaa acgccaccag accagaaccc
    20221 gccgggaaag agataccgat cgggaaacgg gtatgggagt caccaccggt accgacggta
    20281 tccggcagca gcatacggtt cagccaggag tgaatgacgc cgtcacccgg acgcagcgac
    20341 acaccgccac ggttcataat gaagtccggc agcgtgtggt gcgtgttcac gtcaactggc
    20401 ttcggatacg ccgcggtgtg gcagaaagac tgcatcacca ggtcagccga gaagcccagg
    20461 cacgccaggt ctttcagttc atcacgggtc atcgggccgg tggtgtcctg ggaacctaca
    20521 gaagtcattt tcggttcaca gtacgcgccc ggacgaatgc ctttcacgcc acaggcacgg
    20581 cctaccattt tttgcgccag cgagaagccg cgatcgctct cagcgacatc tttcgcctga
    20641 cggaacacat cactgtgcgg cagaccaagt gcttcacgcg ctttggtggt caggccacgc
    20701 ccgataatca gcggaatacg gccaccagca cgcacttcat caatcagcac gtcggttttc
    20761 agttcgaagg tcgccagcag ttcgccggtt tcgtggttac gcacttcacc tttgtacggg
    20821 taaacgtcaa tcacgtcgcc catgttcagg ttagagacgt cgacttcgat tggcagtgca
    20881 cccgcgtctt ccatcgtgtt aaagaagatg ggtgcaattt taccgccgag gcacaaacca
    20941 ccgccgcgtt tgttcggcac atgtggaata tcatcgccca taaaccacag aacggagtta
    21001 gtggcggatt tacgcgaaga acccgtaccc acaacgtcac cgacgtacgc cagcgggaaa
    21061 cctttctgtt gcagagcttc gatttgcttg atcggaccaa caacaccagg ctggtctggc
    21121 tcaatacctt cacgggcgtt tttcagcatc gccagcgcgt gcagtgggat atccgggcgt
    21181 gaccacgcat ccggtgccgg agaaaggtca tcggtgttag tttcgccagt gactttgaag
    21241 acagtaacgg tcagtttttc agccagcgcc gggcgattca ggaaccattc ggcatccgcc
    21301 caggactgca taacctgctt cgcatattcg ttgcctgctt tcgctttctc ttctacgtca
    21361 tagaagttat cgaacatcag cagcgtgtga gaaagtgctt tggcagcaat aggtgccagt
    21421 ttggcatcat ccagcgcgtc gatcagcgga tgaatgttgt aaccaccctg catggtgccc
    21481 agcagttcga tggctttttc cggagtcagc agaggggatt tggcttcgcc tttcgcgata
    21541 gcagccagga agcctgcttt gacataggcg gcttcatcga cgcctggggg aacacggttg
    21601 gttaacagat ctaacaggaa ttcttcttcg cccgcgggcg ggtttttcag cagctctaca
    21661 agtgcggcca tttggtttgc atccaggggt ttgggcgcaa tcccctcagc ggcacgctca
    21721 gctacgtgct tacggtattc ttctagcacg acggttctcc tcgctctcat tgtcatagtg
    21781 cggcaggcga ttctcttcac gctcctgtga gacagcagtt tgtagggtaa atgcccagta
    21841 ccgcaacggg cagaatagca ggattttgac gaggtgttaa tctgtttaca aaaaagcaac
    21901 ataaaaaagt ggctgaatcg ttaaggatgg tctagagatt gtttccctcc gtaaaaactt
    21961 cgttaattcg catggtgata atcacctttc tcaacgaatc ccaagattag tcaaaattta
    22021 aactaccgcc tctttatact cggattcaca gcacctgcgg gtggcagttc gccgaccatt
    22081 gcgatttcct tgagatccga attatgaaaa tgactttgcc gtttaaaccc catgtgctgg
    22141 cgctaatttg cagtgccggg ctttgtgccg cctctaccgg gctatatata aaaagccgca
    22201 cagtggaagc gcctgtggaa ccgcaatcga cacaactggc tgtgtctgac gctgccgcgg
    22261 ttacgtttcc tgcaacggtt tccgcacctc ccgtaacacc cgccgtcgtc aaatccgcat
    22321 tcagcactgc acaaatagat caatgggtcg cgcccgtcgc gctgtatccc gacgccctac
    22381 tttcgcaggt gctgatggca tcaacctatc cgacaaacgt tgctcaagca gtgcaatggt
    22441 cgcacgataa ttcacttaaa caaggcgatg ctgctattca ggcggtatct gaccagccgt
    22501 gggacgccag cgttaaatca ctggtggcct ttccacaatt gatggcattg atgggcgaaa
    22561 acccgcaatg ggtgcaaaac ctgggcgatg cttttctggc ccagccgcag gacgtgatgg
    22621 actcggtaca gcgattgcgg caactggcgc aacaaaccgg ctcgctgaag tcatcaaccg
    22681 aacagaaagt tattaccaca acgaagaaag ctgtaccggt aaaacagaca gtcacggcac
    22741 ccgtcatacc atccaataca gttttaactg ccaaccccgt cattacagag ccggcaacaa
    22801 ccgtcatttc cattgagccc gccaatcctg atgtggtcta tattcccaac tacaacccaa
    22861 ccgtggttta cgggaactgg gccaatactg cgtatccgcc ggtttatctg ccaccaccag
    22921 ccggagaacc gtttgttgac agctttgtac gcggattcgg ctatagcatg ggcgttgtta
    22981 ccacgtacgc actattcagc agcatcgact gggacgacga cgatcatgac catcatcatc
    23041 atgacaatga tgattatcat caccacgatg gcggtcatcg tgacggtaat ggctggcaac
    23101 acaacggcga caacatcaat atcgacgtca acaatttcaa ccgtatcacc ggtgagcatc
    23161 ttactgataa gaatatggca tggcggcaca atccaaacta ccgtaatggt gtgccctatc
    23221 atgatcagga tatggcaaag cggtttcatc aaaccgatgt caacggcgga atgagcgcca
    23281 cgcaattacc tgccccaacg cgcgacagcc agcgtcaggc ggcagcaaat cagtttcagc
    23341 aacgaacaca cgccgcacca gtcattacac gagataccca acgtcaggca gcggcacagc
    23401 ggtttaatga agctgaacac tatgggagct atgacgactt ccacgacttc agccgtcgcc
    23461 aactactgac ccagcaacaa aaggacgccg ctcgtcagcg ttatcagtcc gcctcgcctg
    23521 agcagcgcca ggcagttcgc gagagaatgc agactaaccc gaagatccag cagcgaagag
    23581 aggcagcgcg tgagcgcatt cagtccgcct cgcctgagca gcgccaggcg gttcgcgaga
    23641 aaatgcagac taacccgcag aaccagcagc gaagagacgc agcgcgtgag cgtattcagt
    23701 ccgcatcacc agagcagcgc caggtgttta aggaaaaagt acagcagcgc ccactgaatc
    23761 aacagcaacg tgataacgcc cgccagcgtg ttcaatcggc atcacctgaa caacgtcagg
    23821 tttttcggga gaaagttcag gagagccgcc cacaacgtct aaacgacagt aaccatactg
    23881 tcaggctgaa taacgagcaa cggtcagcag tatgcgaacg tctctctgaa cgtggagcaa
    23941 gaagactgga aaggtaaatt gcagacgtaa aaaaagcggc gtggttagcc gcttttttaa
    24001 ttgccggatg ttccggcaaa cgaaaaatta cttcttcttc gctttcgggt tcggcaggtc
    24061 ggtaatgcta ccttcgaaca cttctgccgc caggcccaca gactcgtgca gagtcgggtg
    24121 cgcgtggatg gtcagtgcga tgtcttcagc atcacaaccc atttcgattg ccaggccgat
    24181 ttcacccagc agctcgccgc cgttagtacc gacaatcgca ccaccgatca cacggtgaga
    24241 ttctttgtcg aaaatcagct tggtcatacc gtctgcgcag tcggaagcga tagcacgacc
    24301 agaagcagcc cacgggaagg tggcggtttc atagctgatg cctttctctt tcgcttcttt
    24361 ctcagtcaga cccacccatg caacttctgg ttcggtatag gcgatggacg ggataacttt
    24421 cggatcgaag tagtgtttct taccggcgat aacttcagcg gcaacgtgac cttcgtgaac
    24481 acctttgtgt gccagcatcg gttgaccgac gatatcgccg atagcaaaga tgtgcggtac
    24541 gttggtacgc agctgtttgt caacgcggat gaaaccacgg tcgtcaactt ccacgcctgc
    24601 tttgcctgcg tcgaggtttt taccgttcgg cacacgacca atcgctacca gcacggcgtc
    24661 gtaacgctgc ggttcagcgg gtgctttttt gccttccatc gtcacataaa tgccgtcttc
    24721 tttcgcttca acggcggtaa ctttggtttc cagcatcagg ttgaatttct tgctgatacg
    24781 cttggtgaag actttaacga tgtctttgtc agctgccggg ataacctggt cgaacatttc
    24841 aaccacgtca atctgtgaac ccagcgcgtg gtaaacggtg cccatttcca gaccgatgat
    24901 accgccaccc attaccagca ggcgttctgg tacttctttc agttccagcg cgtcagtgga
    24961 gtcccagata cgcggatctt catgcggaat aaacggcagt tggatcgggc gagaacccgc
    25021 tgcaatgatc gcgttgtcga agttgatcac ggttttgccg ttctcacctt caacttccag
    25081 ggtgttagcc ccggtgaatt tacccagacc gttgaccact ttgactttgc ggcctttcgc
    25141 cataccagcc agaccaccgg tcagctgatt gatcactttc tctttccagg tacgaatctt
    25201 gtcgatatcg gttttcggtt cgccgaagac gataccgtgt tcagccagcg ctttggcttc
    25261 ttcgataact tttgctacgt gcagcagtgc tttagaaggg atacagccga cgttcaggca
    25321 aacaccgcca agggtgttgt aacgttctac gattacggtt tccagaccta aatcagcgca
    25381 acggaaggca gcggagtaac ctgcggggcc tgccccaagt accacgacct gagttttgat
    25441 ttcagtactc atcatgacct ctatatattt atctccggcg gtcatacccg tcgtctttca
    25501 ggccgcagcg gcgttagctt cacgccctca ccccagtcac ttacttatgt aagctcctgg
    25561 ggattctggc gcttgctacc ttgctgcacc cagaaatcca tagggtatgt gaagtaatac
    25621 cctaaccacc accgggtcgt tctatccgtc ggtattttac aaaattgtta acaattttta
    25681 aacaacaaac ggcaaccgat ttgtctattc gctaataacc tcaatacatt catgagatta
    25741 ccagaaaaaa gccggccgtt gggccggctc ttttacttac atcaccagac ggcgaatgtc
    25801 agacagcgtg ttgttaatga tggtaatgaa acgggcacca tcagcaccgt cgatcacgcg
    25861 gtggtcgaag gagagagaaa tcggcagcat cagacgcggc acgaactctt taccattcca
    25921 caccggctcc atcgcggact tggaaacgcc gaggatagcc acttccggcg cgttcacaat
    25981 cggcgcgaag tgggtagtac ccaggccgcc gatgctggag atggtgaagc aaccgccctg
    26041 catttcgccc gcagtcagct taccgtcacg cgctttctta gaaatagtca tcagctcgcg
    26101 agacagctcg atgatgcctt tcttgttgac gtctttgaat accggaacaa ccagaccgtt
    26161 cggggtatcc accgccacac cgatgttgat gtatttcttc agggtcagac gctgaccgtc
    26221 ttccgacagc gaactattga agcgaggcat ctgctcaaga gctgcagcaa cggctttcat
    26281 gatgaagaca accggggtga tcttcacatc cagcttacgt ttcgccgctt cttcgttctg
    26341 ctgtttacgg aacgcttcca actcggtgat atcggttttg tcgaagtgag taacatgcgg
    26401 gatcattacc cagttacggc tcaggttcgc accagagatt ttctggatgc ggcccagttc
    26461 cacttcttcg atttcaccaa acttgctgaa gtccaccttc ggccacggca gcatgccagg
    26521 gataccaccg ccagtcgctg ccggagctgc ttctgcacgt ttgatagctt ctttcacgta
    26581 agcctgaacg tcttcgcgca ggatacgacc tttacggcca gtgcccttca ctttcgcaag
    26641 gttaacacca aactcgcgtg ccagacggcg gatcagcgga gtcgcgtgaa cataagcgtc
    26701 gttttcagca aattcagatt tgccttccgc tttcgcagct ggtgctgctg ccggggcttc
    26761 agcttttgct gccggtgccg gcgctgccgc ttcctgtttc gcaggagctg ccgcaggcgc
    26821 tgcgccttca acttcgaaga tcataatcag cgagccagtt ttcactttat cgccaacgtt
    26881 gactttcagt tccttcacga cgcctgcaaa cggcgccgga acttccatag aagctttgtc
    26941 gccttctacg gtgatcagtg actgttcagc ggcaactttg tcgcccactt tcaccatcac
    27001 ttcagtcact tcaacttcgt caccgccgat atccggaacg ttaacttctt tcacgccagc
    27061 cgctggtgca ggggccgctg ccggagctgc ttcctgttta gcggccggag ctgccgcgcc
    27121 tgcttcaccc gcgacttcga agaccataat cagcgagccg gtagacactt tgtcacccac
    27181 gttcactttg atctctttca cggtgccagc aaacggagcc ggaacttcca tagaagcctt
    27241 gtcgccttct acggtgatca gcgactgttc agcttcaact ttatcgccaa ctttcaccag
    27301 gatttcggtc acttcaactt cgtcgctgcc gatatccgga acgttaacgt cttttgccgc
    27361 cgcagccgct ggtgctgctg ccggagctgc ttctttcttc tcttctgcct gagcaggtgc
    27421 agcgtctgct gcaccgtcgg cggaatcgaa aatcataatc agtgcgccgg tctgggtttt
    27481 atcgccaaca gagactttga tctctttaac gatacccgcc tgcggagacg gaacttccat
    27541 agaggctttg tcgccttcta cggtgatcag cgactgttcg gcttcaactt tgtcgcccac
    27601 tttgaccagg atctcggtga tttcaacttc atcagccccg atgtccggta ctttgatttc
    27661 gatagccatt attcttttac ctcttacgcc agacgcgggt taactttatc tgcatcgatg
    27721 ttgaatttgg cgattgcgtc agcaaccact ttcttatcga tttcgccacg tttagccagt
    27781 tcgcccagcg ccgcaaccac gacataagaa gcatcaactt cgaagtggtg acgcaggttc
    27841 tcacggctgt cggaacgacc gaagccatca gtacccagta cgcggtagtc gtcagccggt
    27901 acgtaagtac ggacctgctc agcgaacagt ttcatatagt cggtagatgc cactgccgga
    27961 gcgtcgttca tcacctgagc gatatacgga acgcgcggag tttccagcgg gtgcagcatg
    28021 ttccagcgtt cacaatcctg accatcacgc gccagctcgg tgaaggaggt cacgctataa
    28081 acgtcagaac ctacgccgta atctttcgcc aggatctcag ctgcttcacg gacgtgacgc
    28141 aggatagaac cggagccgag cagctgaact ttacctttgc taccttcaat agtttcgagt
    28201 ttgtagatac ctttacggat accttcctca gcaccttccg gcattgccgg catgtggtag
    28261 ttttcgttca gcgtagtgat gtagtagtaa acgttctctt gtttttcacc gtacatacgc
    28321 tccagaccgt catgcatgat gacagcaact tcgtaagcgt aagccgggtc gtaagagata
    28381 cagttcggga tagtcagcga ctgaatgtgg ctgtgaccat cttcgtgctg cagaccttcg
    28441 ccgttcaggg tggtacgacc ggaagtaccg ccgatcagga agccacgcgc ttgctggtcg
    28501 ccagccgccc agcacagatc gccaatacgc tggaagccga acatcgagta atagatgtag
    28561 aacgggatca tcggcagatt gttggtgctg taagaggtcg ccgctgccag ccaggaacaa
    28621 cctgcgccca gctcgttgat cccttcctgc agaatctgac ctttctcgtc ttctttatag
    28681 taagcaacct gctcgcggtc ctgcggggtg tactgctgac cgttcgggct gtaaatacca
    28741 atctgacgga acagaccttc cataccgaaa gtacgcgctt cgtcggcgat gatcggtacc
    28801 agacgatctt tgatcgactt gttcttcagc atcacgttca gagcacgaac gaaagcgata
    28861 gtggtagaga tctctttgct ctgctcttcc aacagcgcgc cgaagtcttg caggctcggc
    28921 agctcaagct tctcggtgaa gttcggctga cggcttggca gataaccgtg cagtttctga
    28981 cgctgagcgt gcagataggt atgctcttca gaaccttccg ggaaggtgat gtacggcagt
    29041 ttttcgatat ctgcatcaga caccggcaca ttgaaacggt cgcggatatg acgcacaccg
    29101 tccatgttca ttttcttaac ctggtgcgcg atgtttttac cttcagccgc gtcgcccatg
    29161 ccataacctt taatggtatg agcaaggatt actgtcgctt tgcctttggt ttcctgcgct
    29221 ttcttgaatg cagcgtagat tttcttcgga tcgtgaccac cacggttcag tgcccagatc
    29281 tgctcgtcag tccagtctgc aaccagtgct gcggtttcag gatatttacc gaagaagtgt
    29341 tcacgaacgt acgcaccatc tttcgatttg aaggtctggt agtcgccgtc aacggtttcg
    29401 ttcatcagct ggatcagttt accgctggta tccttacgca gcagttcatc ccaacggcta
    29461 ccccacatca ctttgatcac gttccagcca gcaccttcga agatgccttc cagttcgttg
    29521 atgatcttgc cgttaccggt gaccgggccg tcaagacgct gcaggttaca gttgataacg
    29581 aagaccaggt tatccagttt ttcacgggta gcgatggtga tcgcaccttt ggattccggt
    29641 tcgtccattt caccgtcacc gaggaacgcg taaacggttt gtttagaggt atctttcagg
    29701 ccacggtgtt ccagatattt caggaattta gcctggtaaa tagcaccaat cggacccaga
    29761 cccatagata cggtcgggaa ctgccagaat tccggcatca gtttcgggtg cggataggaa
    29821 gagaggccat tgccgtgaac ttcctgacgg aagttatcca gctgctcctg agtcagacga
    29881 ccttccagga aagcacgagc gtacacgccc ggggagatgt ggccctggaa gtaaaccagg
    29941 tcgccgccat cctgctcgtt gcgtgcacgg aagaagtggt taaagcacac atcataaatg
    30001 gttgcggaag actggaagga cgccatatgg ccgcccagtt cgaggtcttt tttcgacgca
    30061 cgcagcaccg tcatgatggc gttccagcgg atagctgaac gaatacggcg ttccagttcc
    30121 agattacccg gatactccgg ttgttcttca acggggatgg tgttgatgta gttgctgata
    30181 cctgtgcctg cggctacgtt tacaccgcct ttgcgggctt cagcaagcag ttggtcgatc
    30241 agatactgag cacgctcaac accttcttca cggatgaccg attcgatcgc ctggagccag
    30301 tcgcgagttt cgatcggatc cacgtcattt gggaaacgtt ctgacatggg ttattcctta
    30361 tctatctaat aacgttgagt tttctggaac ctgtcccatt gaactctcgc cggaaagctc
    30421 aataagacag gttctacgtt tagttgccgc gcttttatat gcgcttgatt tacaacatct
    30481 tctggataat ttttaccaga aaaatcacta attctttcgt tgctccagac gacgcagaga
    30541 acgctcacgg cggctctctt cacgacttct gtcgagcaaa atttcttcga taaaggccag
    30601 atggcgatgc gatgcttcgc gcgcttcttc cggcttaccg gccataatcg cttcaaatat
    30661 gcgggtgcgg tgactactca ccagcggcag catctcgcga cgcgaataga gcaattcgaa
    30721 gttctggcgg acattctggg ccaacatcgg ctccatacac cttagcagat gaagcagaac
    30781 cacattgtgg gccgcttcgg tgacggcaat ctgatactgg agtacggcgt ttgattccgc
    30841 gtccagatcg ccagactgct gcgccagctc tatggcgtgg tggagttcac ggatgcgttc
    30901 cttgtcttca tcggtactac gcagcgcggc gtaataagcg gcgatacctt ccagggcgtg
    30961 tcgtgtttcg agcaagtcat actgtgactc aggatggtcg gagagcagct ccaccagcgg
    31021 atcgctgaag ctttgccata ggctgctctg gacaaaagtg ccgccaccct ggcgacgaag
    31081 caacaagccc ttcgcttcga gacgttgaat cgcctcacgc aaggagggac gggagacgtc
    31141 aaactgtttt gccagttcgc gttccggtgg gagtttttcg cccgggcgga gagtgccttc
    31201 gaggatcaaa aactccagtt gctgctcaat cacatcggag agttttggtt ggcggatttt
    31261 gctgtaggcc atgagttcct gtcttaagcc acttgccgaa gtcaattggt cttaccaatt
    31321 tcatgtctgt gacgctaaag taacaaagta ttcaccttat gtccatacag gttttgattg
    31381 aaatcatgaa actgtgcaca ttttaacaac ttgacatata taacgtttca aagttgtaac
    31441 tatgcacaaa tgtagacttt acgtaggaaa ggagtttttt aacgattatt aaactataaa
    31501 aatccgaatt gaaccgattc acttaccaat tttgtgattt ttaattcaat taaaacgaat
    31561 ttaaattcat tctacatatt gagaggggtt gaggctgagc tttacaaacg gtttcttttt
    31621 aagcaactca tcttcaacca tgcataaagc gggtgcattc gctgccgcat accattattc
    31681 ttgatctgac ggaagtcttt ttgtaacaat tcaaacttct ttgatgtaaa caaattaata
    31741 caacaaacgg aattgcaaac ttacacacgc atcactgcgt agatcaaaaa aacaaccacc
    31801 gcacgaggtt tcatgatgga aggtcaacag cacggcgagc agctaaagcg cggccttaaa
    31861 aaccgccata ttcagcttat cgcgctgggt ggcgcgatag ggaccgggtt attcctgggt
    31921 agcgcctccg taatacagtc cgcagggcca gggattatcc tgggttacgc cattgctggt
    31981 tttatcgcct ttctgatcat gcgtcagctg ggtgaaatgg tggtcgaaga acctgtcgca
    32041 ggctccttta gccactttgc ttataaatac tggggcagtt ttgccggttt cgcctctggc
    32101 tggaactact gggtactgta cgttttagtt gccatggctg agctgactgc cgtgggtaaa
    32161 tacattcagt tctggtatcc ggaaatcccc acctgggttt ctgccgccgt attctttgtg
    32221 gtgattaacg ccatcaacct gaccaacgtt aaagtgtttg gcgagatgga gttctggttt
    32281 gccattatca aagttatcgc ggtggtagcg atgatcatct tcggcggctg gctgctattc
    32341 agtggcaacg gcggcccgca ggcgaccgtt agcaacctgt gggatcaggg tggtttcctg
    32401 ccgcacggct tcaccgggct ggtgatgatg atggcgatta tcatgttctc gttcggtggt
    32461 ctggaactgg tggggatcac cgcagcagaa gctgataacc cggagcaaag tataccgaaa
    32521 gcaactaacc aggttatcta ccgcatcctg attttctata ttggttcgtt agccgttctg
    32581 ctctcactga tgccgtggac ccgcgttacc gccgatacca gtccgtttgt gctgatcttc
    32641 cacgagttag gcgatacctt tgtggcgaat gcgctgaaca tcgtggtact gactgcggcg
    32701 ctctccgtgt acaacagctg cgtatattgc aacagccgta tgctgtttgg tctggcacaa
    32761 cagggtaatg cgccaaaagc gctggcgtct gtcgataaac gtggtgtacc agtaaatacc
    32821 attctggtgt ctgcactggt aacggcgttg tgcgtactga ttaactacct tgccccagag
    32881 tccgctttcg gactgttaat ggcgctggtg gtatctgcac tggtaatcaa ctgggcgatg
    32941 attagcctgg cgcatatgaa attccgtcgc gccaagcagg aacaaggcgt ggtaactcgc
    33001 ttccctgctc tgctttatcc gctgggtaac tggatctgcc tgctgtttat ggcggcggta
    33061 ctggtgatta tgctgatgac cccaggaatg gcgatttcgg tatacctgat cccggtatgg
    33121 ctgatcgtgt taggtatcgg ctatctgttt aaagagaaaa ccgccaaagc cgtaaaagcg
    33181 cattaatctc tctacgccct cacccgtaca gggtgagggc aataatcttt acaccaacgc
    33241 cccgtaaatc gtcagtagtg caatcaccac cacgaccacg aacgaggttt tcttcgccat
    33301 tgaaaccgct gccttcggcg tctccacctt atcgacatgc ggttcacgcg ccagagagaa
    33361 ctgcgccaga cgcgttaaca cctgatactg cgaagtatgg aaatcaccca gcgaagcgaa
    33421 ccaggccggt aacgctttct caccatgacc gatcaaggca tataccacac ccgcaagacg
    33481 aaccggcacc caatccagta catgaagcac ggcatcaatg ccggactgta aacgatgatg
    33541 cggcgtctga tatcgcgcca gccagtattg ccatgcacgc aaaaacgcat accccatcag
    33601 cgtaacgggt ccccaggttc cccccacaat cagccagaac agcggtgcaa gataaaaacg
    33661 aaagttaatc cacagcaatg cattttgcag ctcacgcaaa tactcacgtt cgtcgcagcc
    33721 tgccgggacg ccgtgaatca tggtgagttc gccagccatc gtggcacggg catggctatc
    33781 attacgtgaa gcagctgtca gataagcatg ataatgaaga cgaactttac ctgcgccaat
    33841 acacagcaaa ccaatcagca gccacaccag tagcgtggga acgttgaaca atactccctg
    33901 caatgcgcgt aacagtaaaa aagtcacgcc catcgcaata atggtcatgc ctaacgtgcg
    33961 cccgagagaa aaatgtttca cccgccgaaa gaacgcttca agacgatgat caagctgcca
    34021 gtgctcgccc aacttaaaca ggcgctcgaa aattaacacc agtaaggttg taaatagcgt
    34081 catgttgtct ccttgctgac cagcacacga aaccgtgccc aatcaaatgc aggaccggga
    34141 tcggttttcc gatccggcgc aatatcacaa tggcccgtca tgtttttagc gatatccgga
    34201 tagcaatcaa tcagtgcccg cgtaaccgcc gcaagctgtt gatactgcgc atcggtatac
    34261 gccagcgtat cggtgccttc aagctcaatc ccaatagaaa aatcattgca gcgttcgcgc
    34321 ccctgatact gagagactcc cgcatgccat gcacgtttat cgaaaggaac atactggact
    34381 atttcaccat cacggcgaat caaacagtga gcggagacgc gcaaatgggc gatctcagca
    34441 aagaaaggat gtgcctgcgg atcaatagtt ccagtgaata atgcgtcgat ccacggaccg
    34501 ccaaactcgc ctggcggcag gctaatattg tgcaccacca gcagggtggg tgtttcgtca
    34561 tccgggcggc aatcgtaatg tggtgaggga acgcggcgcg cgccaaccag ccacccctgt
    34621 tctaacaaca tgcaggatct ccttatatgt ggtgctaata cccggttcag agtagcatgt
    34681 ttctacctta tgattcgtta gctatctgga gttttaacat gccgcctcgc cgctataacc
    34741 ctgacacccg acgtgacgag ctgctggaac gcattaatct cgatatcccc ggcgcggtgg
    34801 cccaggcgct gcgggaagat ttaggcggaa cagtcgatgc caacaatgat attacggcaa
    34861 aacttttacc ggaaaattct cgctctcatg ccacggtgat cacccgcgag aatggcgtct
    34921 tttgcggcaa acgctgggtt gaagaggtgt ttattcaact ggcaggcgac gatgtcacca
    34981 taatctggca tgtggatgac ggcgatgtca tcaatgccaa tcaatccttg ttcgaacttg
    35041 aaggcccatc ccgcgtgctg ttaacgggcg aacgcactgc gcttaatttt gtgcaaaccc
    35101 tttcaggagt tgccagtaag gtacgccact atgtcgaatt gctggaaggc accaacacgc
    35161 agttgttgga tacgcgcaaa accttacccg gcctgcgttc agctctgaaa tacgcggtac
    35221 tttgcggcgg cggagcgaat caccgtctgg ggctttctga tgccttcctg atcaaagaaa
    35281 accatattat tgcctccggc tcagtgcgcc aggcggtcga aaaagcgtcc tggctgcacc
    35341 cggatgcgcc agtagaagtc gaagtagaga atctggaaga acttgatgaa gccctgaaag
    35401 caggagccga tatcatcatg ctggataact tcgaaacaga acagatgcgc gaagccgtca
    35461 aacgcaccaa cggcaaggcg ctactggaag tgtctggcaa cgtcactgac aaaacactgc
    35521 gtgaatttgc cgaaacgggc gtggacttta tctccgtcgg tgcgctaact aaacacgtac
    35581 aagcactcga cctttcaatg cgttttcgct aatagttgac agatttatcc gctccatcgc
    35641 gggcggataa tctccccttc cccaactttc ttcgtaacgc ctcgcaaatt tcttgtcttt
    35701 cgctgcaacg aaataaaaaa cctcggaatc tgctttcccg tttcgttttt tgcccctcgc
    35761 ctgtgctgat ggcgtttgcc aaagtagcgc caaccaaatc aaggagcgaa acagatggac
    35821 aagcaacgcg gttttacact tatcgaactg atggtggtta ttggcatcat tgccatttta
    35881 agcgccattg gtattcccgc ttatcaaaac tacctgcgca aagccgcact caccgacatg
    35941 ctacaaacct ttgtgcctta ccgtaccgcc gtagagttgt gcgcgctgga acatggtgga
    36001 ttagatacct gcgacggtgg cagcaatggc attccctcgc ctaccaccac ccgctatgtt
    36061 tcagccatga gtgtggcaaa gggcgtggtg tcgctgaccg ggcaagaaag tctcaatggg
    36121 ctaagcgtcg tcatgacacc gggttgggat aacgcaaacg gcgtcaccgg ctggacgcgc
    36181 aactgcaata ttcaaagtga cagcgcattg cagcaagcct gcgaagatgt cttccgcttt
    36241 gatgacgcca actaaggagc ggcaatgaat attccacagc tcactgccct gtgtctgcgt
    36301 tatcatggag tcttgctgga tgccagcgaa gaggtggttc atgttgcggt agtcgatgca
    36361 ccttcgcatg agctactgga cgcattgcat ttcgctacca ccaaacgtat tgagatcacc
    36421 tgctggacgc gccaacaaat ggaaggtcac gccagtcgca cacaacagac attgcccgta
    36481 gctgttcagg agaagcatca gcccaaagca gagttgctaa ctcgaacgtt acaatctgcg
    36541 ctggaacaac gcgcgtctga tattcatatc gaaccagcgg acaatgccta ccgcatccgc
    36601 ttgcgtatcg acggcgtatt gcatccttta ccggatgttt caccggatgc cggagtcgca
    36661 ttaaccgcca gattaaaagt gctgggaaac ctggatattg cggaacatcg cctgccgcag
    36721 gacgggcaat tcactgtcga actggcagga aacgccgtct catttcgtat tgcgacctta
    36781 ccatgtcggg gtggtgaaaa ggtggtatta aggttgttac agcaggtggg tcaggcactg
    36841 gatgtcaaca cgcttggaat gcagccgtta caactggcgg actttgctca tgccttgcaa
    36901 caaccacagg gactggtgct ggtaactggc cctaccggca gcggcaaaac ggtcacgctt
    36961 tatagtgccc tgcaaaagct gaataccgct gacattaata tttgtagcgt cgaagatcca
    37021 gttgagatcc ccatagccgg actaaaccag acgcaaatcc atccgcgtgc cggactcacc
    37081 tttcagggcg ttttgcgtgc gttattgcgc caggatcctg acgtcatcat gatcggagag
    37141 atccgcgatg gcgaaacagc agagagcgct attaaagcgg cgcaaactgg tcacctggtg
    37201 ttgtctaccc tacacactaa ttccacctgc gaaacgctgg tacgtttaca gcaaatgggg
    37261 gtcgcccgct ggatgctatc atcggcgctt acgctggtaa tagcccagcg tctggtacgc
    37321 aaactttgcc cacattgtcg ccggcagcaa ggggagccca tccacattcc agacaatgta
    37381 tggccatcgc cgctgcccca ctggcaggca cccggttgtg tacattgcta ccacggtttt
    37441 tatggtcgta cggccttatt tgaagttctg cccataacgc cggtcattcg tcagcttatt
    37501 tccgctaata ccgacgttga atcgctggaa acgcacgcac gacaggcggg tatgcgtacg
    37561 ctttttgaaa acggctgcct ggccgtagag caaggcttaa ccacctttga agagttaatc
    37621 cgcgtactgg ggatgccgca tggcgagtaa gcaactctgg cgctggcatg gcataaccgg
    37681 cgacggcaat gcgcaagatg ggatgctatg ggcagagagc cgtactttac tgcttatggc
    37741 actacagcaa cagatggtta ccccactaag cctgaagcga atcgccatca attctgcgca
    37801 gtggcgagga gataaaagcg cggaagtcat tcatcaactg gcgacgctac tcaaagcagg
    37861 gttaacgctt tctgaagggc tggctctgct ggcggaacag catcccagta agcaatggca
    37921 agcgttgctg caatcgctgg cgcacgatct cgaacagggc attgcttttt ccaatgcctt
    37981 attaccctgg tcagaggtat ttccgccgct ctatcaggcg atgatccgca cgggtgaact
    38041 gaccggtaag ctggatgaat gctgctttga actggcgcgt cagcaaaaag cccagcgtca
    38101 gttgaccgac aaagtgaaat cagcgttacg ttatcccatc atcattttag cgatggcaat
    38161 catggtggtt gtggcaatgc tgcattttgt tctgccggag tttgccgcta tctataagac
    38221 cttcaacacc ccactaccgg cactaacgca ggggatcatg acgctggcag actttagtgg
    38281 cgaatggagc tggctgctgg tgttgttcgg ctttctgctg gcgatagcca ataagttgct
    38341 gatgcgccga ccgacctggc ttatagtgcg gcagaaattg ctgttacgca tcccgattat
    38401 gggttcactg atgcggggac aaaaactcac gcagatcttt acgattctgg cgctgacaca
    38461 aagtgcaggc attacttttt tacagggcgt agagagcgtc agagaaacaa tgcgctgccc
    38521 gtactgggtg caacttctga cacaaatcca gcacgatatc agtaacggtc aacccatctg
    38581 gctggcgcta aaaaataccg gtgagtttag cccgctctgt ttgcaattag tgagaacagg
    38641 agaggcatcc ggctctctgg atctcatgtt agacaacctc gcccatcatc atcgggaaaa
    38701 cacaatggcg ctggcggata acctcgcagc cttactggaa ccggcgttgc tgatcataac
    38761 gggaggaatt attggtacgc tggtggtggc aatgtatctg ccaattttcc atttaggcga
    38821 tgcgatgagt gggatgggat aacgctggcg tgttgctcca cgccagcgtt gggagattac
    38881 aggttgttga agatgcggtt ttcttgttcc tgcacacgaa taaacgtggt gcgcttggtc
    38941 agctctttca ggcgtgaagc cccaacgtat gtacaagctg aacgcaggcc gcccaaaata
    39001 tctcgcgcgg tattttcaac cgggcctcgc agcggcagct taacggtttt accttctgct
    39061 gcgcgatatt ccgcaacgcc gccaacgtga cgtttcatcg cagactcgga gctcatgccg
    39121 tagaacagca taaatttctc gccgttctcc tcaacgatgc gaccgccgct ctcttcgtgg
    39181 cccgccagca tgccgccaag catgacgaaa tcggcaccgc cgccaaaggc tttcgccaca
    39241 tcgcccggcg tggtgcagcc accatcgctg acgatcattc cgcccagacc gtgcgcagca
    39301 tcggcacatt cgattaccgc agaaagttgc ggataaccga cgcctgtttt gacgcgagtt
    39361 gtacaaacag aacctgggcc aatgccaact ttaacgatat cggcacctga gaggataagc
    39421 tcctcacaca tttcaccagt cactacgtta ccagcacaaa tggttttggt cggccacgct
    39481 tcacgcgctt tcgcaacgaa ctgcacgaag tgttcggaat aaccattcgc cacgtcaata
    39541 caaacgaagt ttaatgccgg gttcaggtcg agaatctgtt tagttttttc gaaatccgca
    39601 tcagacgtac cggtagaaac catcacatgt ttcagcacat cagcggaaga attgttgata
    39661 aacgcttgcc actcttcgac agaatagtgt ttatgcacag cagtcaaaat atcaaaagaa
    39721 gccagcgcag aggccataga aaatgtgcct acggtgtcca tatttgcggc gataatcggc
    39781 acgccggacc agctctgacc tgaatgtttg aaggtgaatt gacgttccag ttcaacatcg
    39841 gaacggcttt taagagtgga gcgtttaggg cggatgagaa cgtctttaaa acctaacttc
    39901 agatcttctt caatacgcat gtgcggattc ctggggttaa tggctataag ggtaagagcg
    39961 caactccagt gacgctatca tacgcactaa tcaatgcggc gcaagactgc gaaattgtct
    40021 ttttttacgc tacaatccca taaatttacc tggtaaatag tgagcgaacg tttcatcaat
    40081 ttcgctttcg tgcactcatt tttaacgttt tgataatcat gatgaattcc cgggaatata
    40141 aattatgagg tatatagttg ccttaacggg aggcattggc agtggcaaga gtaccgttgc
    40201 caatgcgttt gctgatctcg gaattaacgt cattgatgcc gatattattg cgcgtcaggt
    40261 ggttgaacca ggtgcacctg cgctacatgc cattgctgat cactttggcg ctaacatgat
    40321 tgctgctgat ggaacattgc agcgccgggc cttgcgcgag cggatcttcg ccaacccgga
    40381 agagaaaaac tggcttaacg ccctgctgca tccgctgatt cagcaagaga cgcaacacca
    40441 gatccagcaa gctacttccc cctatgtact gtgggttgtg ccattgctgg tagaaaactc
    40501 actgtataaa aaagcgaatc gagtgcttgt ggtggatgtc agcccagaaa cgcaacttaa
    40561 gcgcaccatg cagcgcgatg atgtaactcg cgagcatgtc gaacaaatcc ttgctgctca
    40621 ggcaacgcgc gaagcccgcc ttgccgtggc agatgacgtc attgataata acggcgcacc
    40681 ggatgctatc gcatcggatg ttgcccgcct gcacgcacac tatttgcagc ttgcgtcgca
    40741 gtttgtctca caggaaaaac cgtaatgcag acccaggtcc tttttgaaca tccactaaat
    40801 gaaaaaatgc gtacatggct gcgcattgag tttttgattc agcaactcac cgttaattta
    40861 cccatcgttg accacgctgg cgcgctgcat ttcttccgta atgtcagtga attactggat
    40921 gttttcgagc gcggcgaagt ccgcactgag ctgttgaaag aacttgaccg gcagcaacgt
    40981 aaactccaga cctggattgg cgtgcctggc gtggaccaga gccgtattga agcattaatt
    41041 cagcagttaa aagcggcggg gagcgtatta atttccgcgc cgcgtatcgg gcaatttctg
    41101 cgtgaagatc gtttgattgc tctggtgcgt cagcgactga gcatcccagg cggctgttgc
    41161 agctttgatt tacctacatt gcacatttgg ctgcatctac cccaggcgca gcgcgacagc
    41221 caggtagaaa cctggattgc cagcctgaac ccgctcaccc aggcacttac catggtgctg
    41281 gatttaattc gccagtcggc ccccttccgt aaacaaacca gcctgaatgg tttttatcag
    41341 gataacggtg gcgatgccga cttgctgcgc ctgaatctgt cgctcgattc acagctttat
    41401 ccgcaaattt ccggacataa gagccgtttt gccattcgtt ttatgccgct ggacactgaa
    41461 aacggacagg taccggaacg tctggatttc gaactggcct gttgctaagg agtaaaaatg
    41521 tcagaaacta ttacggtgaa ttgcccaacc tgcgggaaaa cggtggtgtg gggtgaaatc
    41581 agcccgtttc ggccattttg ctccaaacgt tgtcagctga tcgacctcgg agaatgggct
    41641 gctgaagaaa aacgaatccc cagcagtggc gatctttccg aaagcgatga ctggagcgaa
    41701 gaaccaaagc agtgacattt gtctgatgcc gcacgtaggc ctgataagac gcggacagcg
    41761 tcgcatcagg catcttgtgc aaatgtcgga tgcggcgtga acgccttatc cgacctacaa
    41821 aaacaaattt atcaatgagt tagaaatccc tttaggcctg ataagacgcg ccagcgtcgc
    41881 atcaggcatc gtgtgcgaat gtcggatgcg gcgaaaacgc cttatctgac ctacagacgt
    41941 ttaagcttcg caattaccgg ttcattggct ggcggaaaat catcggcatt aagaccgacc
    42001 agcgacatcc actcaccggg ttgcccttct ttaccccacg gctccccttc ccagcgttcg
    42061 accagccaaa accacagtgt tatatgcctg tccgggaatt catattccag tttttcaaat
    42121 agcgaaaaat gttggggggt aatcccgact tcttcctgaa gttcacgcac caccgcctgt
    42181 tccggcgttt cacccatttc aattttaccg ccgggaaact ccagtttatt cgccatgtgc
    42241 gcatctgctg cgcgacgcgt tataaagatt tcattgttct cgttgcgaat aatacctacc
    42301 gcaatttgca gctttttcat tgtcttaaac ctataaaaaa ggcgcagaat cctgcgcctt
    42361 ttacttcaac agttagcttt tattgcaggc ggccatggca ctgcttgtat tttttaccag
    42421 aaccgcacgg gcaaggatcg ttacgtccta ctttgcgctc tccggtttgc gccgccagtg
    42481 cagctgcggc tgcagagtcg tcatcctgat ggctaagctg ctgcatttgc gctaaacgct
    42541 cggcttccat acgacgctgt tgttccagct cctcaacctc ttcaggcata cgtacctgaa
    42601 ctttgctcag cgtactgata acttcatatt tcaacgactc cagcatcgct gcaaacatgg
    42661 agaacgattc acgtttgtat tcctgcttcg gatctttctg tgcgtagcca cgcaggtgga
    42721 taccctgacg cagatagtcc atcgctgcca ggtgctcttt ccacagggag tcaagcgttt
    42781 gcagcatgac gcctttctcg aagtgacgca tcatctcagc accaaccact tcttctttac
    42841 gctgatacac ttcgatggac tgcgccagaa tgcgctcacg cagcgtctct tcatgcagtt
    42901 ctggttcttt atccagccac tcggcaattg gcaaatcgag gtcgaaatcg ttcttcagac
    42961 gttcctgcag ccccggaata tcccacattt cttccagcga ctgtggtgga atgtaggcat
    43021 caatggtcgc tttgaacaca tcttcacgaa tgctgttaat ggtttcgctc acatcgctga
    43081 catccaacag ttcgttacgc tgggagtaaa tggcgcgacg ctgatcgtta gccacgtcat
    43141 catattccag cagttgctta cgaatgtcga agttacggct ttcaacttta cgctgggcgt
    43201 tggcaatcgc tttagtcacc cacgggtgtt caatggcttc gcctggcttc atacccagtt
    43261 tacgcatcat gccggatact cggtcggaag caaaaatacg catcagcgca tcttccatcg
    43321 acaggtagaa acgggaagaa ccagcatccc cctgacgacc agaacgaccg cgcaactggt
    43381 tatcgatacg acgggattcg tgacgctcgg taccgatgat atgcaggcca cctgcttcca
    43441 gtaccgcatc gtgacgtacc tgccagtcgg ctttaatttt ttcaatttgc tctgcggtcg
    43501 gattttccag cgcggcaact tctgcctgcc agctaccacc gagcacaata tctgtaccac
    43561 gacccgccat attggtcgcg atagtcaccg cagccggata acctgcctga gcaacaatcg
    43621 ccgcttcgtt ggcgtggaat ttggcgttca ggacgttgtg cttaataccg gctttggtca
    43681 gttcgtttga caccagctcc gatttttcga tggagatagt acccaccagc accggctggc
    43741 ctttcgcagt acgttctttg atatcttcaa tgatcgcctg aattttttcc gcttcagtca
    43801 tgtagaccag gtccggcaga tctttacgaa tcattggacg gttggtcgga acaacgacgg
    43861 tatccagctt gtagattgag ctaaattcga aagcttcggt atcagcagta ccggtcatcc
    43921 ccgccagttt ttcatacaga cggaagtagt tctggaaggt gatcgaagcc agcgtttggt
    43981 tttcgttctg gatctgcaca ccttctttcg cttccacagc ctggtgcaga ccatcggacc
    44041 agcgacggcc ctgcatggta cgaccggtgt gttcgtcaac gatgataact tcaccatctt
    44101 taacgatgta gtcgacgtca cgggtaaaca gcgcatgagc gcgcagcgcc gccgttacgt
    44161 ggtgcatcag catgatgttg gccggagagt acagagactc cccttcatcc atgatgccct
    44221 ctttcaccag cagttcttca atcagcacca gaccacgttc ggtcaggttc acctggcgag
    44281 atttttcgtc caccgagaag tggccttcgc cctggaaggt ttcggagtct tctttttcct
    44341 gacggatcag gtgcggaata attttattca cgcgtttata catttccgag ctgtcttctg
    44401 ccgggccgga aatgatcagc ggtgtacgcg cttcatcgat caggatggag tccacttcgt
    44461 ccaccagcgc atagtgcagt ttacgctgta cacgttcttc agggctgaac gccatgttgt
    44521 cgcgcaggta gtcaaagccg tattcgttgt tcgtaccgta agtgatgtca gctgcgtaag
    44581 cttcgcgctt tgccggtgct ggcatgcccg gcaggttgat accgacagtc aggccaagga
    44641 attcaaacag cggacggttg ttttcggcgt cacgttgcgc caggtagtcg ttgacggtaa
    44701 ctacgtgcac gcctttaccg gttagtgcgt tcaggtaagc aggcagcgtt gcggtcaggg
    44761 tttttccttc accggtacgc atttcggcga tgcagcgttc gttaagaacc ataccgccga
    44821 gtaactgaac gtcgaagtga cgcataccaa agacgcgctt acttgcctca cgtaccacgg
    44881 cgaaagcttc cgggatcaga ttttccagca cttcgccttt ttccagacgt gcacgaaact
    44941 ctgcggtttt ccctttcagt tcttcgtcgg agagtttttc catctccggt tccatggcat
    45001 tgatgatgtt gaccactttg cgcatccggc gcagggtgcg atcgttacga ctaccgaaaa
    45061 ctttagttaa caatttgatt agcataataa aatctcaaac gccccgcatt gcggagttaa
    45121 taaaatgaag taaaggttta ttgttgttag gtgaggcgtt gagggccagc acggatgcct
    45181 tgcgcctggc ttatccagac gggcgtgctg aattttgctt gtggggtaaa atgcgcataa
    45241 tcaatgcgat aacccttttc agacggcgtg ccttcctggg tcagcagcgc gctgagcgta
    45301 tccagtaatg caagatgttg cgcctgaaga ggcaaagatt cttcagcaac gggcagtgtt
    45361 tgcggtgcca ttgcgaaaga aagatgacgg attaccgtgc gaatggcatg ttgatgccag
    45421 taatcaacgg aatagttcga attcgggcgg cgtgtgttcg cttccagcaa ggccaattga
    45481 ccaaagttaa ctttggctga aggctcgtgg ttgcgggttg tcgcttttgc gggcgcgttt
    45541 ggttcggcgg cgttgctgag cgcaggcaaa cctaaactcg ccgcaaccat ccctaataag
    45601 agatgcggcc agaagtagcg tttaccaaac tgtcgccagc gcgtcagtat tccactcacg
    45661 ttattgccat cccgatcata ttcaaacgta tttagcgcac aaatcttatc attaaagcct
    45721 gcagtccaca gcacgaatga agataagttg tgcggaaaag tgcttaagaa aacagcgttc
    45781 gcaccgtttt ttatagctct tataaaattc aaaaaaaaac gactggttca cctggccgga
    45841 gagagtgcca gatttgccag tcgaatttta tacgacagta taaatgtcgt tatgccagta
    45901 cagctgaagg cgctttgaag gccaacggca gttctgcgtc gtcctggaag gtcacatatt
    45961 cccaggcttc ctgtttcgcc aggacagcct gcagcagttt gttattcagt gcatgaccgg
    46021 atttataagc ggtaaatgca ccaataatat tgtgaccaca catgaacaag tcaccgatcg
    46081 catcgagcat tttgtgacgc acaaattcgt cttcaaaacg caggccgtct tcgttcagta
    46141 cgcgataatc gtcaacaacg atggcacaat cgaagctgcc gcccaggcac aaaccacggg
    46201 actgcagata ttcgatatca cgcatgaaac cgaacgtacg cgcacggctg atctggcgca
    46261 taaacgcatc agcggagaag ttcatcgcat agcgctggtt gctggaatca atagccggat
    46321 ggttaaaatc gatggtgaaa tccagcgaaa aaccattgta cggcttaaat tcagcccact
    46381 tatcgccatc ttcgacacga acagtctctt tgatgcgaac aaattttttg gcgcagttca
    46441 actcgtcgat accggcgtca agcagcaggt atacaaacgg agcggcgctg ccgtccatga
    46501 tcgggatttc cggcgcgtta acttcgataa caatgttatc gatgcccaag cccgcgagag
    46561 cagcattgag gtgctctacg gttgaaatcc gtacatcatg ctcgttgacc agacacgtac
    46621 agagcatggt atcacgcaca gatttggcat cggccgggaa atctaccggt ggattcaagt
    46681 cggtgcgacg atagatgacc ccggtgttgg ccggcgcagg gcgtaacgtc agggtgactt
    46741 tcttgccggt atgtaaaccg acacccgtcg cctgaacgat acgtttaagt gtcctttgtt
    46801 tgatcatcgt attatctcgc caaattacct atccaaccga agtgtactat acattcggcg
    46861 ggccagttta gcacaaagag cctcgaaacc caaattccag tcaattctta atcagcttgc
    46921 ttacgcagga atgctgggat atccagataa tccggctctt tcgcagtttg cggcgcattg
    46981 tcattcacga ctttagcaac cggcttctgc tcctgggtca gcggagctat cccatgctgc
    47041 tggtagcgat ccatcactgg ctgctgaacc tgcttattgg tcaccagagt gatttcagga
    47101 cgtttgtcca tgccgatacc tgtcgcaaca acggttacgc gcagctcgtc attcatatcc
    47161 gggtcaagag aagtaccgat aaccacagtc gcgttgtcgg aagcaaatgc acggatggtg
    47221 ttacctaccg tttcgaactc atccagacgc aggtcgaagc ccgccgtgat gttaaccagc
    47281 acgccgcgcg cgccagacag gtcgatatct tccagcagcg gagaagagat agccatttca
    47341 gcagcttctt ccgcacggtc ttcaccgctc gccacgccag aacccatcat tgcgtagccc
    47401 atctcagaca ttacggtgcg tacgtctgca aagtccacgt tcatcaaacc cggacgagta
    47461 atcagttcag cgataccttg cacagcgcct ttcagtacat cgttcgctgc gccaaacgca
    47521 tccagcaggg agataccgcg gcccagaact ttcagcagtt tgtcgttcgg gatagtgatc
    47581 agagagtcca catgcttgga cagttcagtg atcccctgct ccgcgaatgc catacgcttc
    47641 ttgccttcaa agttgaaagg cttagtgacg acagcaacgg tcaggatacc caaatctttt
    47701 gccacttcag cgacgactgg tgctgcacct gtaccggtac caccacccat acccgcagca
    47761 ataaagacca tgtctgcacc ttccagcgcc gcacgcaatg catcgcgatc ctcatcagcc
    47821 gcattgcggc caacttctgg attagcgcca gcgcccagtc ctttggtgat accgctaccg
    47881 atttgaatcg tctgtccaac cgctgtttta cgcagcgctt gtgcatcggt atttaccgcg
    47941 aagaattcaa caccttcaat gcgctcgcgc accatgtgtt caacagcatt accgccgccg
    48001 ccgccgacgc cgatgacttt aatcaccgcg tcattggtaa gttccattgg ttcaaacata
    48061 gtttctctcc gatttgtgcc tgtcgcctga ggccgtaatc atcgtcggcc tcataaaaat
    48121 taaaactctt ttcgcagcca actattgagt cgcttgatcc acgagccaac tgatgctgta
    48181 acacgttttt ctacttcagc ttcaccgtta agatgtgact ctttcccata gtgaagcaat
    48241 cccaccgccg tcgaataata cggctcctga gcataatccg ttaaaccggt aatgttcagc
    48301 ggcgcgccga tacgcacttg cgtatgaaac acgcgctgag cacaggctgc aagaccttcg
    48361 atctgcgctg cgccaccggt taatacaatg cctgccgcca ggtgatgttt aaccccttgt
    48421 tggcgaagct tttcctgcaa ctgcaatatc tcttcgttga ccaggttgag cagctcggta
    48481 tagcgcggct cgatcacctc tgccagtgtc tgacgttgca gactccgtgg cggacgacca
    48541 cctacgctcg gcacttccac gctctcatct tttccaacga tggaacccag cgcacaaccg
    48601 tggcgaactt taatcgcttc ggcgtcgctt ggcggcgtgc caaaggcgta agcgatatca
    48661 ctggtcacga cattgccagc ataaggaatt accttagtgt ggcgcaatgc cccaccggta
    48721 taaacggcga tatccattgt accaccaccg atatcgacga cgcagacacc cagttcacgt
    48781 tcatcttccg tcaataccga ataacttgat gccagtccgg caaatatcag ttggtcaact
    48841 ttcagcccac aacgttcaac cgctttgacg atgtttttcg ccatatcgtt gtgacatgtg
    48901 atcaggtgca cttttgcctg catccgcacg cccgaaagtc ctaccggatt cttgatccct
    48961 tcctgatagt caatcgcata ctcttgcggg atcacatgca gcacacgatg ctcatcgcgc
    49021 acacgcaccg atttcgcggt atggacgacg ttttccacat cttcttgcgt cacttcttct
    49081 tcagaaatag gcaccatacc aatttcattc tggcagctga tgtgcttacc agaaagcgcc
    49141 agatataccg aagagatctg acaatctgcc atcaattctg cctggtcaat ggcgcgttgt
    49201 acgcacttga ccacggattc gaggtcgttc accccgcctt tatccatacc acgcgacggg
    49261 cagctgccca cgccaatgat attgaccata ccgtcgggca gaacttcccc tactaaagcg
    49321 gcaaccttcg cggtaccaat ctccagtcct actaccagtt ttctgtccgt cgccttgatc
    49381 attgttgttc tgcctgtgcc tgattttgtt gctgagtaga ttcctctggc ggcaagggcg
    49441 cccagcctac tgccgctcca gagtcataac gcaaatcaac gtagctaatc cgtttgccat
    49501 cggtttgcgc ctgctgctgt aaaaccggat aaagttctac aaagcgagcc aaacgtttca
    49561 tcgtatcgcc ccggccaaga ttgagcttaa tatcgttatt cagcgtcaac tgccaggaac
    49621 gccgcgcggt catcgccgct tccttcagag taaatctgtc ctttgccagc atctgcccca
    49681 tttcgcgata gccctgcaac acttcattgg cgctgccttc cgggccatac agcattggaa
    49741 gcacctgctt gctggtgcgt tctggcggca cgctgaaggt atttccttcc gcgtctacca
    49801 tatgttgatc attccaccgc gcaatcggca catattcaac cagatgaatc ttcaattcat
    49861 caggccactg ctttctgacg ctcacctgct taatccacgg caggcgttgt tctatttgcg
    49921 tctggatgat gttgacatcc tgggtcataa aggtacccgg ctcacccaat gccaggatcg
    49981 actgccggat atcgtcatta cgtgtgtaat ggcgttcacc ggtcaacacc agctttgaga
    50041 gcggcaggcg ttgcgcatct tccatccagc ccaacacgac ccagccgctc accaacactg
    50101 tcgttaaaac ggtcagcagg aaaaggatcc ccgccagacg cgttccatta ttgcggcgag
    50161 aagaaacctc ttcttcgctg tttcgcgtgt tcagagcagc ctgcgacata ttagtccgcc
    50221 agttccagaa ttcgtactac caactgcgag aagctcatac ctgcctgacg tgccgccatc
    50281 ggcaccaggc tgtggctggt catacccggt gaggtattgg cttccagcag ataaaactgt
    50341 ccatcgctgt ccagcataac gtcaatacgt ccccatcctt tgcaacctaa cgtcgtccat
    50401 gctttcagca ctaatgcctg caaattggcc tcttgtgacg cttccagacc tgcggggcag
    50461 aaatactgtg tctcatcaga gagatacttc gcctcataat catagaaggt tccggacggt
    50521 tgaatacgta ttgacggtaa aatttcttca ccgagtatcg caaccgtgaa ctccggccca
    50581 cttagccatt tttcaatcaa tacttcttca tcgtgctgaa atgccaatct taatgcatct
    50641 tgtagagcat tttctgctac tacttttgac attcccacac tggaaccttc gcggctcggc
    50701 ttaacgataa ccggcaaacc cagagcagaa atttctgcta actgcttatc gctcaggcct
    50761 ttttcaaact ctgcgcgggt taacgctacc cacggcgcga ccggtaaacc ggcaccttgc
    50821 catagaagtt tgctgcgtag tttatccatt gaaagcgcag atgccatcac tccgcttccg
    50881 gtataaggca agcccatcag ctcgagcatc ccctgcagcg taccatcttc accgccgcga
    50941 ccgtgtagcg cgataaacac tttctgaaag cccatcgact tcagttgcgt cacgtcgact
    51001 tctttcgggt cgacaggata cgcgtcaata ccgccttcac gcagtccggc taacaccgct
    51061 gcgccagaat tcagagaaac ttcccgctca gcggaggtcc cacccaacag gaccgcgatt
    51121 ttatcagtca tgttgttctt cctccggagt ttgcggcttc agtttgattt cagctaaaga
    51181 acgggcaatt tttccaatat taccagcccc ctgaacgaga atcaggtcgt taccggttaa
    51241 taccggtgcc agcatctcgg ctacccgcgc cggatccggc acaagaatgg gatcaatttt
    51301 cccacgtcca cgaattgtgc gacacagcga acggctgtcc gctcccggaa ttggcgcttc
    51361 gccagccgga tacacttcca gcatcaacag ggtatcaacc tgcgtcagca cattggcgaa
    51421 atcatcatac aggtcgcgcg tacgggtaaa acggtgcggc tgaaacagca ttaccaggtt
    51481 tttatccggc cagcctgcgc gcgccgcttt aatggtggcg tccacttccg tcgggtggtg
    51541 gccgtagtca tcgaccagca ttgccgtacc gcttttacca ttcactggct ccagcgggaa
    51601 ttcaccgagg aaatcaaaac ggcgaccagt cccctggaag ctttcaagcg cccgcaaaat
    51661 agcctcgtcg tcaatgccct cttccgtagc aaccgcaacc gcagctgcgg cgttcagcgc
    51721 gttatgacga cctggcgcat tcagggtgac gcgcatcggc tctttgtcct ggcgcagcag
    51781 cgtaaagtgc ccctgcgggc caatctgctg ataatcttct acacgcacgt cggcatcttc
    51841 gctgaagccg taagtcgtgg tctgacgccc cactcgcggt aacaattcgc ggatcaccgg
    51901 atcatcaaca cacatcaccg cacgaccgta aaacggcagg ttgtgcagaa aattaataaa
    51961 agtctgtttt aaattctcaa agtcgccctg gtaggtatcc atgtggtcgg cttcgatatt
    52021 ggtgacaatc gccaccatcg gttgcagatg caggaacgat gcatcactct catctgcttc
    52081 ggcaatcagg taccgaccat gccccaaacg cgcatgaacc cccgccgctt ttaccagccc
    52141 gccgttaacg aaggttgggt cgagccccgc ttctgcgtag atgctggaaa ccatcgcggt
    52201 ggttgtcgtt ttgccgtgcg ttccggcaat ggcgatgcca tgacgaaaac gcattaactc
    52261 agccagcatt tcggcacgac ggatcaccgg aatacgcgct tcatgagcgg cgacaatttc
    52321 cgggttatcg gcagaaatcg cgctggaaac aacgaccacg ctggcatcac gtacgttttc
    52381 cgggcgatgg ttgaaataaa tcgtcgcacc cagattcatt aactgctgcg tgaccggatt
    52441 tggcgctaaa tcggaaccac tgatctgata accttcattg gccagaactt cggcaatacc
    52501 gcccataccg gcaccaccaa tgccgacaaa atgtatgtgc cgaacgcgac gcatttcggg
    52561 cacgatggaa cgcagttttg ccaattgttg tgtattcatt ctttacgcca ttaacttctt
    52621 aaattcatac gatgcaaaag gcatcgctac aattacgccc gggcaacccg gctcacttca
    52681 tttgccactc gctcggtggc atccggaatg gatgcagcgc gggcgcgttc tgccatggtt
    52741 aataaggttt ctcgcgacca cccggccagg gtgttggcga cagcatccac gctaagctgt
    52801 ggctgctcga taattttggc tgcgcccgct ttttccagcg gtagcgcatt ccagtattgc
    52861 tggcggtctt tatgttgaaa cggcacaaac aacgccggta gtcctgccgc ggcgatttca
    52921 ctcaccgtta acgcaccgga gcggcaaacg acgacatccg cccacgcata cgccgccgcc
    52981 atatcatcaa taaattccgt cactttatgc tgcggttgcc ccgcttcggc atacgcctgt
    53041 tcaacggatt gttg
//
LOCUS       DACAOP010000021        50845 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.021, whole genome shotgun sequence.
ACCESSION   DACAOP010000021 DACAOP010000000
VERSION     DACAOP010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 50845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50845
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.021"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..423
                     /locus_tag="IT892_001416"
     CDS             <1..423
                     /locus_tag="IT892_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134649.1"
                     /translation="KAGKIKHWLAHIHTLKPTLPELEILWGQAITSDADRNAAVNALH
                     QQGVQQLFVYLPDESVYCSEKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFLEGYS
                     FRDSARFAVACAAISRASGSLNNPTLSADNALSLVPMV"
     gene            complement(479..1729)
                     /locus_tag="IT892_001417"
     CDS             complement(479..1729)
                     /locus_tag="IT892_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAP3134650.1"
                     /translation="MDVMRSVLGMVVLLTIAFLLSVNKKKISLRTVGAALVLQVVIGG
                     IMLWLPPGRWVAEKVAFGVHKVMAYSDAGSAFIFGSLVGPKMDTLFDGAGFIFGFRVL
                     PAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFAR
                     LLSPATESSQVSFNNLSFTETPPKSIIEAAATGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGVGGWFGFAHASLESILGYLLAPLAWVMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTGGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(1829..2770)
                     /gene="rihB"
                     /locus_tag="IT892_001418"
     CDS             complement(1829..2770)
                     /gene="rihB"
                     /locus_tag="IT892_001418"
                     /EC_number="3.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosylpyrimidine nucleosidase"
                     /protein_id="HAP3134651.1"
                     /translation="MEKRKIILDCDPGHDDAIAMMMAAKHPAIDLLGITIVAGNQTLD
                     KTLINGLNVCQKLEINVPVYAGMPQPIMRKQIVADNIHGETGLDGPVFEPLTRQAEST
                     HAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFT
                     PSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSD
                     IMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCD
                     ELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH"
     gene            2900..3598
                     /gene="yeiL"
                     /locus_tag="IT892_001419"
     CDS             2900..3598
                     /gene="yeiL"
                     /locus_tag="IT892_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311082.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator YeiL"
                     /protein_id="HAP3134652.1"
                     /translation="MKEIHNNDLKQQLMSESAFKDCFLTDVSADTRLFHFLARDYIVQ
                     EGQQPSWLFYLTRGRARLYATLANGRVSLIDFFAAPCFIGEIELIDKDHEPRAVQAIE
                     ECWCLALSMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
                     LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFIHDGLLTKSKKGYLIKNRKQLSGLA
                     LEMDPENKFSGMMQ"
     gene            complement(3669..4919)
                     /locus_tag="IT892_001420"
     CDS             complement(3669..4919)
                     /locus_tag="IT892_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAP3134653.1"
                     /translation="MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGG
                     IMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVL
                     PAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFAR
                     ILSPATEPSQVTFENLSFSETPPKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGIGGWFGFANASLESIFGYVLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVA
                     YLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(5013..5951)
                     /locus_tag="IT892_001421"
     CDS             complement(5013..5951)
                     /locus_tag="IT892_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HAP3134654.1"
                     /translation="MSELKISPELLQISPEVQDALKNKKPVVALESTIISHGMPFPQN
                     AQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFV
                     VAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTV
                     VCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFDVSIRLDSASEIARA
                     MAVKWQSGLNGGLVVANPIPEQFAMPEHTINAAIDQAVAEAEAQGVIGKESTPFLLAR
                     VAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLAG"
     gene            complement(5939..6880)
                     /locus_tag="IT892_001422"
     CDS             complement(5939..6880)
                     /locus_tag="IT892_001422"
                     /EC_number="2.7.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine kinase"
                     /protein_id="HAP3134655.1"
                     /translation="MREKDYVVIIGSANIDVAGYSHESLNYADSNPGKIKFTPGGVGR
                     NIAQNLALLGNKAWLLSAVGSDFYGQSLLTQTNQSGVYVDKCLIVPGENTSSYLSLLD
                     NTGEMLVAINDMNISNAITAEYLAQHGEFIQRAKVIVADCNISEEALAWILDNAANVP
                     VFVDPVSAWKCVKVRDRLNQIHTLKPNRLEAETLSGIALSGREDVAKVAAWFHQHGLN
                     RLVLSMGGDGVYYSDISGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFAESV
                     RFAQGCSSMALSCEYTNNPDLSIANVISLVENAECLN"
     gene            complement(7303..8994)
                     /gene="fruA"
                     /locus_tag="IT892_001423"
     CDS             complement(7303..8994)
                     /gene="fruA"
                     /locus_tag="IT892_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIBC"
                     /protein_id="HAP3134656.1"
                     /translation="MKTLLIIDANLGQARAYMAKTLLGAAARKAKLEIIDNPNDAEMA
                     IVLGDSIPNDSALNGKNVWLGDISRAVAHPELFLSEAKGHAKPYTAPVAATAPVAASG
                     PKRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAAAD
                     LVIVAADIEVDLAKFAGKPMYRTSTGLALKKTAQELDKAVAEATPYEPAGKAQTATTE
                     SKKESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGGGS
                     AFALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYIAKLIS
                     TQLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILEGLTHWLQTMGTANAV
                     LLGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYGPMAAIMAAGMVPPLAMGLATMV
                     ARRKFDKAQQEGGKAALVLGLCFISEGAIPFAARDPMRVLPCCIVGGALTGAISMAIG
                     AKLMAPHGGLFVLLIPGAITPVLGYLVAIIAGTLVAGLAYAFLKRPEVDAVAKAA"
     gene            complement(9011..9949)
                     /gene="fruK"
                     /locus_tag="IT892_001424"
     CDS             complement(9011..9949)
                     /gene="fruK"
                     /locus_tag="IT892_001424"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP3134657.1"
                     /translation="MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGIN
                     VAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGE
                     VTDFNFSGFEVTPADWERFVTDSLSWLGQFDMVCVSGSLPSGVSPEAFTDWMTRLRSQ
                     CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIEAAHALREQGIA
                     HVVISLGAEGALWVNASGEWIAKPPSVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLR
                     LATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN"
     gene            complement(9949..11079)
                     /locus_tag="IT892_001425"
     CDS             complement(9949..11079)
                     /locus_tag="IT892_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused PTS fructose transporter subunit IIA/HPr
                     protein"
                     /protein_id="HAP3134658.1"
                     /translation="MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGML
                     AREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPEGVTWGDGQVAYVAIGIAAS
                     SDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNEMLTLDIV
                     ASDLLTLQALNAARLKEAGAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVS
                     RAANAFDVDGETAAMLVSVAMNDDQPIAVLKRLADLLLDNKADRLLKADAATLLALLT
                     SDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVTNLDGTGKPANGRSL
                     MKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA"
     gene            11447..12628
                     /gene="setB"
                     /locus_tag="IT892_001426"
     CDS             11447..12628
                     /gene="setB"
                     /locus_tag="IT892_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetB"
                     /protein_id="HAP3134659.1"
                     /translation="MHNSPAVSSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTD
                     EVHARPAMVGFFFTGSAVIGILVSQFLAGRSDKRGDRKSLIVFCCLLGVLACTLFAWN
                     RNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGP
                     PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMQKELPLATGTIEAPRRNRRDT
                     LLLFVICTLMWGSNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFA
                     KRLGKRFLMRVAAVGGVCFYAGMLMAHSPVILLGLQLLNAIFIGILGGIGMLYFQDLM
                     PGQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKD
                     V"
     gene            complement(12625..12879)
                     /locus_tag="IT892_001427"
     CDS             complement(12625..12879)
                     /locus_tag="IT892_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HAP3134660.1"
                     /translation="MECRPGCGACCTAPSISSPIPGMPDGKPANTPCIQLDEQQRCKI
                     FTSPLRPKVCAGLQASAEMCGNSRQQAMTWLIDLEILTAP"
     gene            13034..13606
                     /gene="yeiP"
                     /locus_tag="IT892_001428"
     CDS             13034..13606
                     /gene="yeiP"
                     /locus_tag="IT892_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007750416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P-like protein YeiP"
                     /protein_id="HAP3134661.1"
                     /translation="MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFS
                     DVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEE
                     ELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
                     GLVIQVPEYLSPGEKIRIHIEERRYMGRAD"
     gene            13829..15295
                     /locus_tag="IT892_001429"
     CDS             13829..15295
                     /locus_tag="IT892_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAP3134662.1"
                     /translation="MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLT
                     DRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLN
                     AKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
                     APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHV
                     SFPGTMVDRIVPAATDESLVEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVA
                     GVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDE
                     QAPTLQIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHQGRE
                     TDWSLLALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLRE
                     VFGDDLPDNPHFVQAIEQAWQQIVQFGAHQALLNTLKI"
     gene            15413..16399
                     /locus_tag="IT892_001430"
     CDS             15413..16399
                     /locus_tag="IT892_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP3134663.1"
                     /translation="MTRTNLITGFLGSGKTTSILHLLAHKDPNEKWAVLVNEFGEVGI
                     DGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQIL
                     DLLTAPVYEPWIDLRATLCILDPRLLLDEKSASNENFRDQLAAADIIVANKSDRATPE
                     SEQALQRWWQQNGGDRQLIHSEHGKVDGHLLDLPRRNLAELPASAAHSHQHVVKKGLA
                     ALSLPEHQRWRRSLNSGQGYQACGWIFDADTVFDTIGILEWARLAPVERVKGVLRIPE
                     GLVRINRQGDDLHIETQNVAPPDSRIELISSSEADWNALQSALLKLRLATTA"
     gene            16438..17151
                     /gene="lpxT"
                     /locus_tag="IT892_001431"
     CDS             16438..17151
                     /gene="lpxT"
                     /locus_tag="IT892_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kdo(2)-lipid A phosphotransferase"
                     /protein_id="HAP3134664.1"
                     /translation="MIKNLPQIVLLNIVGLALFLSWYIPVNHGFWLPIDADIFYFFNQ
                     KLVESKAFLWLVALTNNRAFDGCSLLAMGMLMLGFWLKENAPGRRRIVIMGLVMLLTA
                     VVLNQLGQALIPVKRASPTLTFTDINRVSELLSVPTKDASRDSFPGDHGMMLLIFSAF
                     MWRYFGKVAGLIALIIFVVFAFPRVMIGAHWFTDIIVGSMTVILIGLPWVLLTPLSDR
                     LITFFDKSLPGKNKHFQNK"
     gene            17563..18129
                     /gene="mepS"
                     /locus_tag="IT892_001432"
     CDS             17563..18129
                     /gene="mepS"
                     /locus_tag="IT892_001432"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional murein DD-endopeptidase/murein
                     LD-carboxypeptidase"
                     /protein_id="HAP3134665.1"
                     /translation="MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVG
                     SETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTF
                     REQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHAST
                     SSGVIISSMNEPYWKKRYNEARRVLSRS"
     gene            18310..19866
                     /locus_tag="IT892_001433"
     CDS             18310..19866
                     /locus_tag="IT892_001433"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HAP3134666.1"
                     /translation="MFIRAPNFGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYD
                     TLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDK
                     KTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
                     VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIA
                     GIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQ
                     FYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQKMIVPLTQHLFEL
                     IARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERD
                     MLKEQEATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTET
                     ITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPLPLDDFVR
                     WLKKPYTPQW"
     gene            19948..21762
                     /locus_tag="IT892_001434"
     CDS             19948..21762
                     /locus_tag="IT892_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416682.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP3134667.1"
                     /translation="MIVRILLLFIALFTFGVQAQAIKESYAFAVLGEPRYAFNFNHFD
                     YVNPAAPKGGQITLSALGTFDNFNRYALRGNPGARTEQLYDTLFTTSDDEPGSYYPLI
                     AESARYADDYSWVEVAINPRARFHDGSPITARDVEFTFQKFMTEGVPQFRLVYKGTTV
                     KAIAPLTVRIELAKPGKEDMLSLFSLPVFPEKYWKDHKLSDPFATPPLASGPYRVTSW
                     KMGQNIVYSRVKDYWAANLPVNRGRWNFDTIRYDYYLDDNVAFEAFKAGAFDLRMEND
                     AKNWATRYTGKNFDKKYIIKDEQKNESAQDTRWLAFNIQRPVFSDRRVREAITLAFDF
                     EWMNKALFYNAWSRTNSYFQNTEYAARNYPDAAELVLLAPMKKDLPSEVFTQIYQPPV
                     SKGDGYDRDNLLKADKLLNEAGWVLKGQQRVNATTGQPLSFELLLPASSNSQWVLPFQ
                     HSLQRLGINMDIRKVDNSQITNRMRSRDYDMMPRVWRAMPWPSSDLQISWSSEYINST
                     YNAPGVQSPVIDSLINQIIAAQGNKEKLLPLGRALDRVLTWNYYMLPMWYMAEDRLAW
                     WDKFSQPAVRPIYSLGIDTWWYDVNKAAKLPSASKQGE"
     gene            21763..22857
                     /locus_tag="IT892_001435"
     CDS             21763..22857
                     /locus_tag="IT892_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter permease YejB"
                     /protein_id="HAP3134668.1"
                     /translation="MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEF
                     GNAGVLPGAGGEGVRASHAQTGVGNISDSNYRGGRGLDPEVIAEITHRYGFDKPIHER
                     YFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
                     YNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLPWY
                     QKITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWK
                     HVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTL
                     YIFTLIGLLLNIVSDISYTLVDPRIDFEGR"
     gene            22857..23882
                     /locus_tag="IT892_001436"
     CDS             22857..23882
                     /locus_tag="IT892_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3134669.1"
                     /translation="MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIAND
                     KPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPWLKQRLENNGWVLWAPIRFGA
                     TSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL
                     AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIIILSSVVQPNFWWLLAITVLFGWMSL
                     VGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTL
                     TSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILLSLLIFIGEAVRDA
                     FDPNKAV"
     gene            23884..25473
                     /gene="yejF"
                     /locus_tag="IT892_001437"
     CDS             23884..25473
                     /gene="yejF"
                     /locus_tag="IT892_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter ATP-binding protein
                     YejF"
                     /protein_id="HAP3134670.1"
                     /translation="MTQTLLAIENLSVGFRHQQTVRTVVNDVSLQIEAGETLALVGES
                     GSGKSVTALSILHLLPSPPVEYLSGDIRFHGESLLHASDQTLRGVRGNKIAMIFQEPM
                     VSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGG
                     ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQGELNMGMLFITHNLS
                     IVRKLAHRVAVMQNGRCVEQNYAATLFASPTHPYTQKLLNSEPSGDPVPLPEPASTLL
                     DVEQLQVAFPIRKGILKRIVDHNVVVKNISFTLRAGETLGLVGESGSGKSTTGLALLR
                     LINSQGSIIFDGQPLQNLNRRQLLPIRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVH
                     QPTLSAAQREQQVIAVMHEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILD
                     EPTSSLDKTVQAQILTLLKSLQQKHQLAYLFISHDLHVVRALCHQVIILRQGEVVEQG
                     PCARVFATPQQEYTRQLLALS"
     gene            complement(25477..25821)
                     /locus_tag="IT892_001438"
     CDS             complement(25477..25821)
                     /locus_tag="IT892_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134671.1"
                     /translation="MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVAL
                     KLLSPDGDNAWSVMYKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGV
                     AIAEPFSNYNPF"
     gene            complement(26154..27344)
                     /gene="bcr"
                     /locus_tag="IT892_001439"
     CDS             complement(26154..27344)
                     /gene="bcr"
                     /locus_tag="IT892_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Bcr"
                     /protein_id="HAP3134672.1"
                     /translation="MTTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPA
                     GSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTLVFAAAAVACALANTIDQLI
                     VMRFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVW
                     LSWHYIFWILALAAILASAMIFFLIKETLPPERRQPFHIRTTIGNFAALFRHKRVLSY
                     MLASGFSFAGMFSFLSAGPFVYIEINHVAPENFGYYFALNIVFLFVMTIFNSRFVRRI
                     GALNMFRSGLWIQFIMAAWMVISALLGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDE
                     FPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSAWPMIWSIAFCATSSILFCLYASR
                     PKKR"
     gene            complement(27372..28067)
                     /gene="rsuA"
                     /locus_tag="IT892_001440"
     CDS             complement(27372..28067)
                     /gene="rsuA"
                     /locus_tag="IT892_001440"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase RsuA"
                     /protein_id="HAP3134673.1"
                     /translation="MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGEIVRNAAFKLLPE
                     HDVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAWKLHAAGRLD
                     IDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLHNEKDL
                     TKPAVLEVITPTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGGITLDADLAPGE
                     YRPLTEEEIASVV"
     gene            28216..29976
                     /locus_tag="IT892_001441"
     CDS             28216..29976
                     /locus_tag="IT892_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP3134674.1"
                     /translation="MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAEL
                     ARLARGRVLVLAHVKELVAQNHAKYQALGLEADIFAAGLKRKESHVKVVFGSVQSVAR
                     NLDAFQGEFSLLIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLGKGW
                     IYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQYDFSRLQAQS
                     NGLFSEADLNRELKKQQRITPHIISQIMEFAAMRKGVMIFAATVEHAKEIVGLLPAED
                     AALITGDTPGAERDVLIENFKAQRFRYLVNVAVLTTGFDAPHVDLIAILRPTESVSLY
                     QQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANT
                     FWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRCRE
                     CDTVLVDPDDMLKAALRLKDALVLRCSGMSLQHGHDEKGEWLKITYYDEDGADVSERF
                     RLQTPAQRTAFEQLFIRPHTRTPGIPLRWITAADILAQQALLRHPDFVVARMKGQYWQ
                     VREKVFDYEGRFRLAHELRG"
     gene            30101..30385
                     /gene="rplY"
                     /locus_tag="IT892_001442"
     CDS             30101..30385
                     /gene="rplY"
                     /locus_tag="IT892_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HAP3134675.1"
                     /translation="MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDH
                     DKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA"
     gene            complement(30524..31531)
                     /gene="yejK"
                     /locus_tag="IT892_001443"
     CDS             complement(30524..31531)
                     /gene="yejK"
                     /locus_tag="IT892_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein YejK"
                     /protein_id="HAP3134676.1"
                     /translation="MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELH
                     RVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGF
                     VLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
                     PESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAE
                     RQNVRQQVYSYCNEQLQAGEEIELKSLSKELAGVSEVSFTEFAAEKGYELEESFPADR
                     STLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGG
                     N"
     gene            31713..31940
                     /locus_tag="IT892_001444"
     CDS             31713..31940
                     /locus_tag="IT892_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejL family protein"
                     /protein_id="HAP3134677.1"
                     /translation="MPQISRYSDEQVEQLLAELLNVLEKHKAPTDLSLMVLGNMVTNL
                     INTSIAPAQRQAIANSFARALQSSINEDKAH"
     gene            31960..33720
                     /gene="pbgA"
                     /locus_tag="IT892_001445"
     CDS             31960..33720
                     /gene="pbgA"
                     /locus_tag="IT892_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin transport protein PbgA"
                     /protein_id="HAP3134678.1"
                     /translation="MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWP
                     TTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLL
                     IDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKL
                     RSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFL
                     EKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFE
                     KQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITAL
                     NQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNR
                     WFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAG
                     RGIPLSEEEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTP
                     ASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDE
                     KPQLSLLLQVLTDEKRFIAN"
     gene            33795..33871
                     /locus_tag="IT892_001446"
     tRNA            33795..33871
                     /locus_tag="IT892_001446"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33829..33831,aa:Pro,seq:ggg)
     gene            complement(33974..36564)
                     /gene="yejO"
                     /locus_tag="IT892_001447"
                     /pseudo
     CDS             complement(33974..36564)
                     /gene="yejO"
                     /locus_tag="IT892_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311108.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter YejO"
     gene            36884..37531
                     /gene="narP"
                     /locus_tag="IT892_001448"
     CDS             36884..37531
                     /gene="narP"
                     /locus_tag="IT892_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite response regulator protein NarP"
                     /protein_id="HAP3134679.1"
                     /translation="MPEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASA
                     IDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAG
                     ADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
                     VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ"
     gene            complement(37742..38794)
                     /locus_tag="IT892_001449"
     CDS             complement(37742..38794)
                     /locus_tag="IT892_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis protein CcmH"
                     /protein_id="HAP3134680.1"
                     /translation="MRFLLGVLMLMISGSALATIDVLQFKDEAQEQQFRQLTEELRCP
                     KCQNNSIADSNSMIATDLRQKVYELMQEGKSKKEIVDYMVARYGNFVTYDPPLTPLTV
                     LLWVLPVVAIGIGGWVIYARSRRRVRVVPEAFPEQSVPEGKRAGYVVYLPGIVVALIV
                     AGVSYYQTGNYQQVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKN
                     PGDIEGWIMLGRVGMALGNASIATDAYATAYRLDPKNSDAALGYAEALTRSSDPNDNR
                     LGGELLRQLVRTDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIE
                     RSIAQAMQHLSPQESK"
     gene            complement(38791..39348)
                     /gene="dsbE"
                     /locus_tag="IT892_001450"
     CDS             complement(38791..39348)
                     /gene="dsbE"
                     /locus_tag="IT892_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="HAP3134681.1"
                     /translation="MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKP
                     VPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVG
                     MNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHA
                     GDLNPRVWEEEIKPLWEKYSKEAAQ"
     gene            complement(39345..41288)
                     /locus_tag="IT892_001451"
     CDS             complement(39345..41288)
                     /locus_tag="IT892_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HAP3134682.1"
                     /translation="MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAW
                     LLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLL
                     MSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
                     LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIF
                     LTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWT
                     LLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVIGGSLLLFAARG
                     HKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFN
                     TMFTWLMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVA
                     MTVLGLAMACWIAVLAIAEAALRISRGTKTTFSYWGMVAAHLGLAVTIVGIAFSQNYS
                     VERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVLYAEKRY
                     YNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGG
                     LLCLFDPRYRKRVSPQKTAPEAV"
     gene            complement(41285..41764)
                     /gene="ccmE"
                     /locus_tag="IT892_001452"
     CDS             complement(41285..41764)
                     /gene="ccmE"
                     /locus_tag="IT892_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HAP3134683.1"
                     /translation="MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEIL
                     YGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDL
                     FREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS"
     gene            complement(41761..41970)
                     /gene="ccmD"
                     /locus_tag="IT892_001453"
     CDS             complement(41761..41970)
                     /gene="ccmD"
                     /locus_tag="IT892_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HAP3134684.1"
                     /translation="MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHR
                     AILRGVAQQRAREARLRAAQQQEAA"
     gene            complement(41967..42704)
                     /gene="ccmC"
                     /locus_tag="IT892_001454"
     CDS             complement(41967..42704)
                     /gene="ccmC"
                     /locus_tag="IT892_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmC"
                     /protein_id="HAP3134685.1"
                     /translation="MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFA
                     PADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFIGLVWQMKMANLAVAAMAPIGAV
                     FTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAG
                     ILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSIFGFLLLSATLTL
                     MRMRNLILLMEKRRPWVSELILKRGRK"
     gene            complement(42746..43408)
                     /gene="ccmB"
                     /locus_tag="IT892_001455"
     CDS             complement(42746..43408)
                     /gene="ccmB"
                     /locus_tag="IT892_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HAP3134686.1"
                     /translation="MMFWRIFRLELRVAFRHSAEIVNPLWFFLIVITLFPLSIGPEPQ
                     LLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWM
                     VTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
                     LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRIS
                     IQ"
     gene            complement(43405..44022)
                     /gene="ccmA"
                     /locus_tag="IT892_001456"
     CDS             complement(43405..44022)
                     /gene="ccmA"
                     /locus_tag="IT892_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HAP3134687.1"
                     /translation="MLEARELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLL
                     RLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDG
                     DTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAIDVN
                     GVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTRAA"
     gene            complement(44041..44643)
                     /gene="napC"
                     /locus_tag="IT892_001457"
     CDS             complement(44041..44643)
                     /gene="napC"
                     /locus_tag="IT892_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type protein NapC"
                     /protein_id="HAP3134688.1"
                     /translation="MGNSDRKPGLIKRLWKWWRTPSRLALGTLLLIGFVGGIVFWGGF
                     NTGMEKANTEEFCISCHEMRNTVYQEYMDSVHYNNRSGVRATCPDCHVPHEFVPKMIR
                     KLKASKELYGKIFGVIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFEYMDTTA
                     QKSVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMREVEPGF"
     gene            complement(44653..45102)
                     /gene="napB"
                     /locus_tag="IT892_001458"
     CDS             complement(44653..45102)
                     /gene="napB"
                     /locus_tag="IT892_001458"
                     /EC_number="1.9.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HAP3134689.1"
                     /translation="MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQE
                     GAIRMPKEQDRMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISP
                     THFMDSDGKVGAEVAPRRYFCLQCHVPQADTAPIVGNTFTPSKGYGK"
     gene            complement(45099..45962)
                     /gene="napH"
                     /locus_tag="IT892_001459"
     CDS             complement(45099..45962)
                     /gene="napH"
                     /locus_tag="IT892_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HAP3134690.1"
                     /translation="MANRKRDAGREALEKKGWWRSHRWLVLRRLCQFFVLGMFLSGPW
                     FGVWILHGNYSSSLLFDTVPLTDPLMTLQSLASGHLPATVALTGAVIITVLYALAGKR
                     LFCSWVCPLNPITDLANWLRRRFDLNQSATIPRHIRYVLLVVILVGSALTGTLIWEWI
                     NPVSLMGRSLVMGFGSGALLILALFLFDLLVVEHGWCGHICPVGALYGVLGSKGVITV
                     AATDRQKCNRCMDCFHVCPEPHVLRAPVLDEQSPVQVTSRDCMTCGRCVDVCSEDVFT
                     ITTRWSSGAKS"
     gene            complement(45949..46644)
                     /gene="napG"
                     /locus_tag="IT892_001460"
     CDS             complement(45949..46644)
                     /gene="napG"
                     /locus_tag="IT892_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HAP3134691.1"
                     /translation="MSRSAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARASGV
                     RLRPPGAINENAFASACVRCGQCVQACPYDTLKLATLASGLSAGTPYFVARDIPCEMC
                     EDIPCAKVCPSGALDREIESIDDARMGLAVLVDQENCLNFQGLRCDVCYRECPKIDEA
                     ITLELERNTRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHH
                     YRFGWLEGNNGKS"
     gene            complement(46651..49137)
                     /gene="napA"
                     /locus_tag="IT892_001461"
     CDS             complement(46651..49137)
                     /gene="napA"
                     /locus_tag="IT892_001461"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic nitrate reductase subunit alpha"
                     /protein_id="HAP3134692.1"
                     /translation="MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKA
                     PCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLL
                     RMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAAS
                     KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAE
                     MHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYII
                     QNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVA
                     EYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHL
                     LTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPS
                     GTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVS
                     DPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFS
                     RRFKTEEVWPEDLLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFY
                     LQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGE
                     GYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRA
                     FPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAA
                     QLVNKLTLDATDPLSKETDFKKCAVKLEKV"
     gene            complement(49134..49397)
                     /gene="napD"
                     /locus_tag="IT892_001462"
     CDS             complement(49134..49397)
                     /gene="napD"
                     /locus_tag="IT892_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HAP3134693.1"
                     /translation="MHTNWQVCSLVVQAKSERISDISTQLNAFPGCEVAVSDAPSGQL
                     IVVVEAEDSETLIQTIESVRNVEGVLAVSLVYHQQEEQGEETP"
     gene            complement(49387..49881)
                     /gene="napF"
                     /locus_tag="IT892_001463"
     CDS             complement(49387..49881)
                     /gene="napF"
                     /locus_tag="IT892_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HAP3134694.1"
                     /translation="MKIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACI
                     NACENNILQRGAGGYPSVNFKNNECSFCYACAQACPESLFSPRHTRAWDLQFTIGDAC
                     LAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEY
                     LHAH"
     gene            49990..50154
                     /locus_tag="IT892_001464"
     CDS             49990..50154
                     /locus_tag="IT892_001464"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134695.1"
                     /translation="MHTPIGVKPVAGSKEWREAWQKRAFAHISNGYKYIYIAIDSPEI
                     FLLVCSLIRI"
     gene            50289..50777
                     /gene="eco"
                     /locus_tag="IT892_001465"
     CDS             50289..50777
                     /gene="eco"
                     /locus_tag="IT892_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease inhibitor ecotin"
                     /protein_id="HAP3134696.1"
                     /translation="MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQV
                     IQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLENKTLEGWGYDYYVFDKVSSPVS
                     TMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAV
                     VR"
BASE COUNT        12480 a        13748 c        12435 g        12182 t
ORIGIN      
        1 aaagcgggca aaatcaaaca ctggctggcg catattcaca ccctgaaacc cactttaccg
       61 gagctggaaa ttttatgggg acaggcgatc accagcgatg ctgaccgtaa tgccgcagtg
      121 aatgcattgc atcagcaagg tgttcagcaa ctgtttgttt atttgcccga tgagtcagtt
      181 tattgcagcg aaaaggatgg agaacaattt ttgctgaccg cgccagcgca tacgacagta
      241 gacagttttg gtgctgacga tggttttatg gcgggcctgg tatatagctt tcttgaagga
      301 tacagtttcc gcgacagcgc ccgttttgcg gtagcctgcg cggcaatttc gcgcgccagc
      361 ggcagcttaa acaaccctac cctgtctgcc gataacgcgc tttcattagt gccaatggtg
      421 taacaatgtt gccggattcg acgcttgacc gcatcttatc cggctcataa attgcgcact
      481 acgctaaacc aataaagaat cctgcaattg tagcactcat caggttagaa agtgtcgccg
      541 ccgccagcgc gcgtaaacca agttgggcga tttccggcgc acggtgtggc gcaaccgcag
      601 aaaacgcccc caccaccacc ccgatagaac caaagttagc gaaaccgcac aacgcgaaag
      661 aaataatcgc cacggtttta gcatccagag tgccacccgt ttgcagatat ggcgagaaat
      721 tgagataagc gacaaattca ttgatcgcca gcttctgccc aatcaaactc ccggcaagat
      781 ttgcatcact ccagtcaacc cccatcaccc acgccaatgg ggccaacagg taacctaaaa
      841 tggactccag cgaggcatgt gcaaaaccaa accagccgcc aacgccgccg ataataccat
      901 taattaacgc aatgatggcg acaaatgcca taacaactgt cgctacaccg gcggcgattt
      961 tcagcccggt cattgcccct gtcgcagcgg cttcaataat gctttttggc ggtgtttcgg
     1021 tgaaagagag gttattaaag gaaacctgcg aagattccgt agccgggctt aacaggcggg
     1081 caaacaagat cccgcctggg atcgccatta acgatgccgc cagcaaatat tccacaggta
     1141 cgcccagggc ggcgtaacca atcattgtcg aaccagcaat cgaggccatg ccactacaaa
     1201 tcgctgtaaa taattcattg cgattcagac gatcgataaa gggtttgacg atcgccggaa
     1261 tttcgttttg cccgaggaaa atggtggtga ccgcgacgaa tgactcaatc ttgctgatat
     1321 ttaatgcttt ctggaatata ccgccgagaa tgcgaattaa aatccccatc acaccgatgt
     1381 agtagagaat actcaccagt gcagtgacga agataattgc cggtaatacc ctgaaaccaa
     1441 agataaatcc tgcgccatca aacagcgtgt ccattttcgg cccgaccagc gaaccgaaga
     1501 taaatgcgct acccgcgtcg ctgtacgcca tcactttatg cacgccaaaa gcgacttttt
     1561 cagcgaccca acgccctggc ggtaaccaaa gcataatccc gccaatcacg acctgtaaca
     1621 ctaacgccgc gccaacggta cgcaggctga tcttcttctt gtttactgac agcaaaaacg
     1681 caatcgtcag caataccacc attcccagaa cacttctcat gacatccata gttattatct
     1741 cttcatgtca tattgggcga cggctttctg cccatcagaa atagccgggc ttggatcttg
     1801 cgatactgac ccggcttgtt atcaacactt aatgggtttt gatgtagccg cgcacgcact
     1861 cttcgactaa gccccagaac cagtcggtat caatagtgat gccgactttg gtattagcgg
     1921 gcttgccaag aacgcccagc tcgtcgcaga cggtacgccc atagcaaggg ccactgttga
     1981 cgtccacttc gacgtacatc tcctgggttt taatgccatc agggttaatc agataaccga
     2041 tgcaggtggc gtcgtgcacc gggccgccag ccaggccgta gttttcgaac tgcgttttga
     2101 gagtgaagtt catgatgtcg ctgaacagct ctccggcagg gccgcctgcc ctttccatcc
     2161 gtgcaatcac gtccggggtg caaacggtct ggttggtgag atcgaggccc atcatcacta
     2221 atggaacgcc ggaggtgaac accacgcggg ctgcttccgg atcagcaaag atgttgaact
     2281 cggcagatgg cgtgaagttg cctgtaccgt aagcgccgcc cattagcaca atttcacgga
     2341 ttttgggcag gatcgcgggt tgcatacgca ttgccaccgc gatatttgaa agcggaccaa
     2401 ccggcaccag agtgatatcg ccatcgcttg ccatcagggt atcaatgatg tatttcaccg
     2461 cgtgggtact ttctgcctgg cgggtcagcg gctcgaatac cgggccatcc agtccggttt
     2521 caccgtgaat attatcggca acgatttgtt tacgcataat gggttgcggc atccccgcat
     2581 aaaccggaac attaatctcc agtttctggc aaacattcag gccattaatt aatgttttat
     2641 caagcgtctg attacccgct acaatagtga tgcctaataa atctattgcc ggatgtttcg
     2701 ctgccatcat cattgcaata gcatcatcat gacccggatc acaatccaga ataatttttc
     2761 tcttttccat tgtttatttc ctctgtttcc agttgcgtta ttttttctac agcaaagaaa
     2821 attcgaccgg gccgatgatt gaatcttacc aaccgcgtac gtatgctaaa tatgagaaat
     2881 ctcatagcgg ataaacatcg tgaaagaaat ccacaataat gatcttaagc agcaattgat
     2941 gagtgaatcc gcgtttaagg attgcttttt aacggatgtt tcagccgata cgcggctgtt
     3001 tcatttttta gcgcgtgact acattgtgca ggaagggcaa cagccgtcct ggctgtttta
     3061 tctgacgcga ggccgcgcca ggctttacgc cacgcttgct aatggtcgcg tgtcgctgat
     3121 cgatttcttt gccgccccct gttttattgg tgagattgag ttaatcgaca aagaccatga
     3181 accgcgtgcg gtgcaggcta ttgaagagtg ttggtgcctt gcgctctcta tgaaacatta
     3241 ccgcccgctg ttattaaacg acacgctatt tttacgaaaa ctctgcgtca ccttaagtca
     3301 taaaaattat cgtaatattg tttctttaac tcagaatcaa tcatttccgt tagttaatcg
     3361 cctggcagct tttatattac tctcgcagga aggtgatctt tatcacgaaa agcatacgca
     3421 agcggcagag tatttaggcg tttcttatcg acatctttta tatgttctcg cgcaattcat
     3481 tcacgacggt ttattaacta aaagcaagaa agggtatctc attaaaaaca gaaagcagtt
     3541 gtcaggactg gcgctggaga tggacccgga gaataaattc tccgggatga tgcagtaaaa
     3601 attatttgca atagcgcgat tgccggatgc aacgcttaat acgttttatc cggtctacaa
     3661 atcgagcatt acgccagacc aataaagaac ccggcaatag tcgcactcat caggttggaa
     3721 agcgttgctg ctgccagcgc ccgtaaacca agctgggcga tttctggagc acgttttggc
     3781 gaaatagccg aaaatgcgcc aacgacaaca ccgatagaac caaagttagc aaaaccacaa
     3841 agcgcaaagg agataatcgc aatggttttc acttccagcg tgccgcccgt ttgcaggtat
     3901 ggggagaaac tcaggtaagc gacgaattcg ttaatcgcca gtttctgccc aatcaggcta
     3961 cccgcaagat tggcatcact ccagtccaca cccatgatcc acgccagcgg tgccagcaca
     4021 tagccaaaaa tactttccag agaggcattg gcgaaaccaa accagccacc aattccgccg
     4081 ataatgccgt tgatcagcgc aataattgcg acaaacgcca ttaccaccgt cgctacacca
     4141 gcggcgattt tcagcccagt catcgcaccg ctcgccgccg cttcgataaa gctttttggc
     4201 ggcgtttcgc tgaacgacag attttcaaat gtgacctgcg aaggctcggt ggccgggcta
     4261 agaatacgtg caaacaaaat accacctggg atcgccatca gcgatgccgc taacaggtag
     4321 tcaattggta cgcccattcc ggcataacca atcatcatcg aaccagcaat ggacgccatc
     4381 ccgctacaaa ttgcggtaaa caactcgttg cgattcatgc gatcgataaa cggtttaacg
     4441 atcgccggga tctcattttg cccgaggaaa atagttgtga ctgcgacaaa agattcgatt
     4501 ttgctgatgt taagagcttt ctggaaaatg ctgccaagga tgcgaatcag cagccccatc
     4561 acgccaatgt agtacagcag actgatgagc gcagtaacga aaataatcgc cggaagtacg
     4621 cgaaaggcga agataaaacc cgcaccgtca aacaggacat ccattttcgg cccaaccagc
     4681 gaaccaaaaa tgaaggcgct accggcatca ctgtaagaca tcactttatg aacgcctaat
     4741 gccgcctgtt ctactgccca ttttcccggt gggaagtaga gcatgatgcc accaatagcg
     4801 atttgcagca gcagtgcggc tccaaccgtg cgcaaactga tgctcttttt attcactgac
     4861 aacagaaatg ctattgccag taacaccacc atccccacaa cacttctcat tatatccata
     4921 atgattttcc cttcatgccg gtaaacccgg cgtcagcgcc aggttttggt atgcttgatg
     4981 agtacgggcg acggctttct gcccgtcaga aattaacccg cgagacgctg atattctttg
     5041 gcaatttcgc tcgccagaat ggcgttgttg aacaccagct ggatgttgga tttcaggctg
     5101 tcaccgccgg tcagttcagc aacgcgcgcc agcaggaatg gcgtactttc tttaccaatg
     5161 actccctgag cttcagcttc agctaccgcc tgatcgatcg ccgcattgat agtgtgttcc
     5221 ggcatagcaa actgttccgg gatcgggttc gctaccacga ggccaccgtt cagaccgctt
     5281 tgccatttca ccgccattgc acgggcaatt tcgctggcgc tgtcgagacg aatgctgacg
     5341 tcaaacgggc tggtgcggca gaaaaacgca ggcagcgctt tagtctgata gccaattaac
     5401 ggcacaccga aggtttctaa atactcagtg gttaatccta aatcgagaat agatttcgcc
     5461 ccggcacaaa caacggtgac attagtattt gccagttctt gcaaatcggc agaaatatcg
     5521 aaggtatgtt ccgccccgcg atgcacacca ccaattcccc cggtggcaaa tactttaatt
     5581 ccggcaagcg ccgcaataat catcgttgaa gccacagtgg ttgcgccatt ttttccggcg
     5641 gcaacaacaa aaggtaaatc gcgacgacta actttggtca cgttatgccc ttcacgaccc
     5701 agtaattcaa tttcttcttt gcttaacccc actttcatca cgccgccaat aatggcgatc
     5761 gtggcaggta cagcgccctg tttacgaata gtttcttcaa cttcaattgc ggtctgggca
     5821 ttttgtggga acggcatccc gtgagaaata atggtcgatt ccagcgccac aaccggtttt
     5881 ttgtttttta aagcgtcctg cacttccggg gaaatttgta ataattcagg ggaaattttt
     5941 aattcagaca ttctgcgttc tccactaacg atataacgtt ggcaatcgat aaatcggggt
     6001 tattggtgta ttcacaggag agcgccattg acgaacatcc ctgtgcgaaa cgaacagatt
     6061 cggcaaacgg cattccgtct acccaacacg aagcaagtcc cgccatcatg gcatcgcccg
     6121 ctccggtaac attaataaca ttggttttga tcggcgcaga ccagccactt tcaccgctga
     6181 tatcgctgta ataaacgccg tcgccgccca tgctcaatac cagtcggttc aggccatgtt
     6241 gatggaacca ggcagcaact tttgccacat cttcacgccc tgacagcgca atcccactca
     6301 gggtttccgc ttcaaggcgg tttggcttga gagtgtggat ctgatttaga cggtcgcgca
     6361 ctttgacaca tttccatgcc gaaaccggat cgacaaatac gggtacgttg gcggcattat
     6421 ccagaatcca tgccagtgcc tcttcactga tattacagtc cgcgacaatg acctttgccc
     6481 tctgaataaa ttcaccgtgc tgtgcgagat attcagctgt aatagcgttg ctaatattca
     6541 tgtcatttat agcaaccagc atttcaccgg tattatcgag taatgataaa taactcgacg
     6601 tattttctcc cggcacaatc aggcatttat cgacataaac gccagattga ttggtttgcg
     6661 ttagcagcga ttgaccataa aaatcactgc ctacggcgct cagtagccag gctttgttac
     6721 ccagcaacgc caggttttgt gcaatattgc gccctactcc accaggcgta aattttattt
     6781 tacctggatt tgaatccgca taatttaatg attcatgtga atatccggcg acatcaatat
     6841 tcgccgaacc tataattacg acataatcct tttcgcgcat agcacgtcct ctggtaaaaa
     6901 attaccaacc ctgtcaatcc acaagaatat agatactgca aagacggttt aaacatgtgt
     6961 tcatatttaa acatgtgctc atagtatgca tgttttacgt aaagtaaatt accgccagag
     7021 aggcaaaatg ggcagatttg agcaggctca caaaatgcga ttaaatgcct gaattacaaa
     7081 agcgaggaat ttgtgacggg atgcacagaa cagaacaata aaaaagggca gaaaataatc
     7141 tgcccttgag gaaataacct gagtgtttga tgaacgtttg aagtttctac tgaaagataa
     7201 aaccatttaa attcataaaa ttacattcac aaaccggtca ttctctttgc gctcatcaaa
     7261 tgttacagga caggaaattt ctgccctgta acacaccttt tattacgctg ctttcgctac
     7321 tgcgtccact tccggacgtt tcaggaaggc ataggccaaa cccgctacca gcgtaccggc
     7381 aataattgct accaggtaac ccaataccgg cgtaatagcg ccagggatca gcagaacaaa
     7441 cagaccaccg tgcggtgcca tcagtttcgc accaatcgcc attgagattg cgccagtcag
     7501 cgccccaccc acgatacagc acggcagcac acgcatcgga tcacgagcag caaacggaat
     7561 tgcaccttcc gaaatgaagc acagtcccaa taccagagcg gctttgccac cttcctgctg
     7621 cgctttgtcg aatttgcgac gcgccaccat tgttgccaga cccattgcca gcggtggcac
     7681 catacctgcc gccataatcg ccgccatcgg gccataggtt tgagtactca gcagacccac
     7741 accgaatgcg tacgctgctt tgtttaccgg accgcccatg tcagtacaca tcatgccacc
     7801 gaggatcgcc cccagcagaa ccgcattcgc agtccccatg gtctgcagcc agtgagtcag
     7861 cccttcgaga atgccagcaa ctggtttacc gatcaggtag atcatcgcca gaccgaccac
     7921 cagactggaa attagcggaa tgatcaggat cggtttcagc gcctccatac tctgtggcag
     7981 tttcaattgc gtactgatta acttcgcaat gtaaccagcc aggaagcccg caataatacc
     8041 accaatgaag ccagaaccgg tgctgaccgc cagcataccg ccaatcagac ccggagtgag
     8101 gcccggacga tcggcaatgg aaaaggcaat ataacctgcc agtaccggca ccatcagcgc
     8161 aaaggctgaa ccaccaccaa tctgcatcag cgccgcagcc aacgtacccg gctctttaaa
     8221 cgcttcgata ccaaaagcaa aagaaagcgc gatacacaga ccacctgcaa cgaccatcgg
     8281 cagcatgtaa gaaacgcccg tcagcaagtg acggtatgcg cctgcactct ctttcttact
     8341 ttcagtggtc gccgtttgag ctttgcccgc cggttcatac ggcgttgctt cagcaaccgc
     8401 tttatccagt tcctgcgcgg ttttcttcag cgccagaccg gtagaggtac gatacatcgg
     8461 tttaccagca aatttcgcca gatccacttc gatatctgcc gccacaatca ccagatccgc
     8521 tgctgcgact tcttcgggag tgattgcatt acccgcgcca acagaaccac gggtttcaac
     8581 tttcacccac cagccacgtt ttttcgcttc ggtttcaatg gcttcagccg ccataaaggt
     8641 gtgtgctacg ccagtcgggc aagcagtcac cgcaactacg cgtttcggac cgctggcggc
     8701 aactggtgct gtcgcagcga ccggcgcagt gtaaggtttc gcatggcctt tggcttcact
     8761 caggaacagc tcagggtgcg caactgcccg ggaaatatcg cccagccaga catttttacc
     8821 gttcagcgcg ctgtcgttcg ggatggaatc accgagaaca atcgccattt cagcgtcgtt
     8881 cggattgtcg atgatttcca gttttgcttt tcgcgccgcc gcgcccagca gggtcttcgc
     8941 catataggcg cgtgcctgac cgagattagc gtcaataatc agcagcgttt tcattatgcc
     9001 tctcctgctg tcagttaaaa ggttgtaagt cgacgcgcgc catcattgcg gccaactgcg
     9061 gacgatcggt aatacccaca ttgctttgac ttaccgccag ggctgcaaca gctgtcgcca
     9121 gacgcagtgt gtgttcactg gattcacgca tcagcaagcc ataaatcagg ccaccaacca
     9181 tagaatcccc tgcgccaacg gtgcttacga catcgactga cggtggtttg gcgatccatt
     9241 cgccggaggc attaacccaa agcgcgcctt cggcacccag tgaaataaca acatgcgcga
     9301 tgccttgttc acgtagcgca tgtgcagctt caatcacatc tttcatttca ggcagtttac
     9361 ggcctgccca gatttccagc tcgcggcggt taggtttcac cagccacggt gccgctttca
     9421 aacctgctac taacgcttca cggctactat caaagataat gcaaggacac tgactacgca
     9481 ggcgagtcat ccagtcggtg aacgcttccg ggctgacgcc tgacggtaag cttccgctga
     9541 cacagaccat atcgaactga ccgagccagc tcagagaatc agtcacaaag cgttcccagt
     9601 cggcgggggt gacttcaaaa cccgagaagt tgaagtcggt cacttcgccg tctttttccg
     9661 tcagcttaac gttaattcgg gtgcgcccct gtacaacctg gaaacggttg gcaatgccca
     9721 gctcgctgaa cagttgctga aaaccatcct gattgtcttt acccaggaag ccgccaacgg
     9781 tgacatcaat tcccaggtct tttaatactt tggccacgtt gatgccttta cccgccgcat
     9841 gcagaccggt ggttttcacc aggttcactt cgccgcgttc aatttccggg cagaaaccaa
     9901 caaggtcata agccggatta agggtgatag tagcaacacg tctgctcatt atgcgccctc
     9961 cccaagacca gcagcgatag cgtcgccgat tgctttcagc gcctgttcag catctgcacc
    10021 ctgggcggta aagcgtaggc gatgaccttt cttaacgcca agtgccacaa ctttcatcag
    10081 actacgtccg tttgccggtt tgccggtacc atcaaggttt gtcacggtaa tatcactgtt
    10141 aaattgttta atggtattga ccagcatggt acctggacga gcatgcaggc cgtgttcatt
    10201 gcgcaccaca aactccgcgc ttaacacgtc gtcggtcggc gcatcatcgc tggtcagcag
    10261 cgccagcaac gttgccgcat ccgctttcag caagcggtca gctttattgt cgagcaataa
    10321 atcagcgaga cgcttaagaa ccgcgatggg ctgatcgtca ttcatcgcca cactcaccag
    10381 catggctgcc gtttcgccgt ccacatcaaa agcatttgcc gcacggctta ccgcaatcgc
    10441 gctacgcaga ttgccttcgg cgctatcgct cagccagata ccctgtccga gattcagcgg
    10501 ttgttcattg atggctttgg tgacgaaagt ggcgtcaact gcccccgcct ctttcagacg
    10561 cgcagcgttc agcgcctgaa gagtcagcag atcgctggcg acgatatcca gtgtcagcat
    10621 ttcgttgtcg agcttcagct gctcactctg cttttcgccc atcagtaatg cgcgaagttc
    10681 ttctgctgtt gttgctgact tcagttgttc agcaacggaa tcatcgctca gtacgtgggt
    10741 cagctggcgt agcaggccca gatgttcatc cgagctggca gcaataccga ttgccacgta
    10801 cgctacctga ccgtcacccc aggtgacgcc ttccgggaac tgaaatacct gaacgccggt
    10861 tttcagcacc tgatcgcggg tgtcggtagt gccgtgtgga atagcaatac cattgccgag
    10921 gaacgttgag gtttgctgtt cgcgcgccag catgccattg acgtagcctt ctgctacatt
    10981 accggcctgc accagcgccg cagcgacctg gcgaatcgcc tcttctttgt ctccggcctt
    11041 ttcgcccgga tggatgtcct gtacggataa ctggaacata gttctcctct cttgctgaat
    11101 tgaaacgatt cagcctctat gagaaaaaaa gcgccaacct ggcttagggt taaagacaag
    11161 atcgcgctga aacgtttcaa gaaagcataa tacttctgtt tcagcacgca aggaaagccg
    11221 taaagttatg agcaaaagtt tgatgtgctg cacaattttt tgccattttt cctaattgct
    11281 gatgggaaaa tccgttatca gcaatttcat ttcagcagcg tcagcagcca atcagcaaca
    11341 gtgaaatggc attttgacta ttcgtggcgc ttttgatttc gctgtctgtt tattttctga
    11401 caagcagcgt aaactccgcg tcttcctctt ccagtgatcg accagcatgc ataactcccc
    11461 cgcagtctcc agcgcgaaat cgtttgacct gacctcgacg gcgtttttaa tcgttgcctt
    11521 tctcaccggt attgcgggcg ctctgcaaac cccgacactc agtatttttc ttaccgatga
    11581 agtacatgcc cgtccggcga tggtgggatt cttctttacc ggcagcgctg tcattgggat
    11641 tctggtaagt cagtttctcg ccgggcgctc tgataagcgc ggcgatcgca aatcgctgat
    11701 tgtcttttgc tgcctgttag gcgtgctggc ctgcaccctt tttgcctgga atcgcaacta
    11761 ctttgttttg ctattcgttg gcgtctttct tagcagcttt ggctcgaccg ctaacccgca
    11821 aatgtttgcc cttgcccgtg aacatgccga caaaaccgga cgtgaggcgg tgatgttcag
    11881 ttctttttta cgcgctcagg tttcactggc atgggtcatt ggcccaccgc tggcttatgc
    11941 cttagcgatg ggtttcagct ttacggtaat gtatctgagc gcagcggtag cgtttattgt
    12001 ttgcggcgtg atggtgtggc tgtttttacc gtcgatgcaa aaagagcttc cgctggcgac
    12061 cggcacgatt gaagcgccgc gccgtaaccg tcgcgatacg ctgctgctgt ttgtcatttg
    12121 tacattgatg tggggctcga acagcctgta catcatcaac atgccgctat ttattatcaa
    12181 cgaactgcat cttcccgaga aactggccgg tgtgatgatg gggaccgccg ccgggctgga
    12241 aatcccgacc atgttgattg ccggatattt cgccaaacgt ctgggtaagc gtttcttaat
    12301 gcgcgttgct gccgtgggtg gcgtctgttt ttacgcagga atgctgatgg cgcattcacc
    12361 tgtcattctg ttgggcttgc agctgctaaa tgctattttt attggcattc tgggtggcat
    12421 cgggatgctc tattttcagg atttgatgcc cggtcaggca ggttcagcca ccacgctcta
    12481 taccaacacg tcgcgcgtgg gctggatcat cgcaggatca gtggcgggca tcgtcgccga
    12541 gatctggaat tatcacgctg tgttctggtt tgcgatggtg atgattatcg ccactctgtt
    12601 ttgcttactg cggattaaag atgtttaagg cgcggtcagg atttccagat cgataagcca
    12661 ggtcatggcc tgctgacgcg agttaccgca catttcagca ctggcttgta agcctgcaca
    12721 gactttcggt cgcagtggcg aggtgaaaat tttacagcgt tgctgttcat caagctgaat
    12781 gcagggcgta ttggcgggct tgccatctgg cataccggga atagggctgg aaattgaagg
    12841 ggcagtgcaa cacgccccgc aacccggacg gcattccata cgttgttctc ttaaggttaa
    12901 ccaccggatt gatgagcgcg cacagtacca ccttttttgc accagcaaaa gtgcgaatac
    12961 cacttgcccg aaaggcccgt cgcgagtact ttgtcgcgat atttttgaca ttttcgacta
    13021 caggaatttt tcgatgccaa gagcgaacga aattaaaaaa ggtatggtac tgaattacaa
    13081 cggcaaactg ctgctggtta aggatattga tattcagtcg cccactgccc gcggtgccgc
    13141 tacgctgtac aaaatgcgtt tttctgatgt ccgtaccggg ctgaaagtag aagagcgttt
    13201 caaaggtgat gatatcgttg acaccgtgac gctgacccgc cgttacgttg acttctccta
    13261 tgtcgatggc aacgaatatg tctttatgga taaagaagac tataccccgt ataccttcac
    13321 caaagatcag attgaagaag agttgctgtt tatgccagag ggcggcatgc cggacatgca
    13381 ggtgctgacc tgggacggtc aactgctggc gcttgagctg ccgcagaccg ttgatctgga
    13441 aatcgttgaa accgcaccag gcatcaaagg ggcatctgcc agcgcccgta acaaaccggc
    13501 gacattgagc actggtctgg tgattcaggt accagaatac ttaagcccgg gcgaaaaaat
    13561 tcgtatccat atcgaagaac gccgttatat ggggcgtgct gactaacttc agccgcatgc
    13621 agaaaaggga tagctcaggc tgtccctttt ttaatttatt ataccaatct tctattttgc
    13681 gcttcctgaa caccttacgc cctcaatttt cactcgttga ttgatcgccc tcacacttca
    13741 tcgcattaac aatccagacc aatttcaatt gctgtcatat aactttacac tgtcattgtt
    13801 aatttatcgt tactaagacg tgactcctat gaagacaatt gcctccgtta cgctcccgca
    13861 tcatgtacac gctccacgct acgatcgcca gcagttgcaa tcacgtatcg ttcattttgg
    13921 ctttggcgcc tttcaccgcg ctcatcaggc gttactgacc gatcgtgtgc tgaatgccca
    13981 gggcggcgac tgggggatct gtgaaatcag cttgttcagc ggtgatcaac tgatgagcca
    14041 gctccgcgca cagaaccatt tatataccgt gctggagaaa ggtgcggacg gcaatcaggt
    14101 gataattgtc ggtgccgttc acgaatgcct taatgcaaaa ctggattcct tagcggcaat
    14161 tattgagaaa ttttgcgagc cacaggtggc aattgtttcc ctgacgatta ccgaaaaagg
    14221 ctattgtatt gacccggcca ccggtgcact cgacaccagt aatccgcgga ttattcacga
    14281 tctacaaacc cctgaagaac ctcactccgc accgggtatt ctcgtcgaag cactgaaacg
    14341 ccgccgtgag cgcggcctta caccgtttac cgtgctctcc tgcgacaata ttcccgacaa
    14401 tggtcatgtg gtgaaaaacg cggtgctggg aatggcagaa aaacgttcgc cagaactcgc
    14461 cgggtggata aaagagcacg tcagttttcc gggaaccatg gtcgaccgca ttgttccggc
    14521 tgcaaccgac gaatcactgg tggaaatcag ccagcatctg ggggtgaatg atccctgcgc
    14581 gattagctgc gaaccgttta tccagtgggt ggtggaagat aacttcgtcg ctgggcgtcc
    14641 tgcctgggaa gtcgcaggtg tacaaatggt gaatgatgtc ctgccatggg aagagatgaa
    14701 actgcggatg cttaatggca gccactcttt tctcgcttat ctgggttacc tctcaggatt
    14761 cgcccatatc agtgattgca tgcaggatcg cgcatttcgc catgccgcca gaacattaat
    14821 gctggatgag caagcgccga cactgcaaat taaagatgtc gatttaacac aatatgcgga
    14881 taagttaatt gcacgttttg ctaatccggc gctgaaacat aagacctggc aaatcgcgat
    14941 ggatggcagc cagaaattac cgcaacgcat gctggcaggt attcgcatac atcaggggcg
    15001 cgaaacggac tggtcgttgc tggcattagg cgttgcaggc tggatgcgtt acgtcagcgg
    15061 cgttgatgat gccggaaatg ccattgatgt tcgcgatccg cttagcgata aaattcgcga
    15121 acttgttgcg ggcagcagca gtgaacaacg cgtaaccgcc ctgctttccc tgcgtgaagt
    15181 tttcggtgat gatctgccag ataacccgca ttttgtgcag gccatcgaac aagcctggca
    15241 acaaatcgta caattcggcg cacatcaggc gctattaaac accctcaaaa tttaacgatt
    15301 tctgcggtta aagcggatga agctcacctt cgtccgctct ccccttctct tttctgcctt
    15361 ttttagccag gattaacgct cagttaactt accagagtat tgcggagccg ttgtgaccag
    15421 gaccaacctc atcaccggtt ttctcggcag cgggaaaacc acgtcgattc ttcatctgtt
    15481 agcccataaa gatcccaacg aaaaatgggc ggtactggtt aatgaatttg gggaagtcgg
    15541 aattgatggt gctttgctcg ccgatagcgg cgcattgctg aaagagatcc ccggcggctg
    15601 catgtgctgc gttaatggtt tacccatgca ggtagggttg aataccttac tgcgtcaggg
    15661 aaaaccagac cgcttgttga tagagccgac cgggctgggc catccgaaac agatcctcga
    15721 tctgttaacc gcaccagtct atgaaccgtg gatagatctg cgcgccacct tgtgcattct
    15781 cgatccacgc ctgctgctgg acgaaaaaag cgccagcaat gaaaacttcc gtgaccagct
    15841 ggctgccgca gacatcattg tcgccaataa atccgaccgt gcgacgcccg aaagtgagca
    15901 agcgctacag cgttggtggc agcaaaatgg tggcgatcga caattaattc acagtgagca
    15961 tgggaaagtt gacggtcatc ttctggattt gccgcgtcgc aatttagccg agttgcccgc
    16021 cagcgccgcg cattctcatc agcatgtcgt gaaaaaaggg ttagcagcgt taagcctgcc
    16081 agagcatcaa cgctggcgtc gcagtctgaa cagcgggcaa ggatatcagg cctgcggctg
    16141 gatattcgac gctgatacgg tattcgacac cattggcatt ctggaatggg cgcgacttgc
    16201 accggtggaa cgcgtcaaag gcgtgctgcg tattcccgaa gggctggtac gaatcaaccg
    16261 tcagggcgat gacctgcaca ttgaaacgca aaacgttgcg ccaccggaca gccgtattga
    16321 gctgatttcc agcagcgaag ctgactggaa tgccttacag agcgcgctgt tgaagcttcg
    16381 tttagcgact accgcgtaag gttgcctgcg tttttcagta agataattag agaaaatatg
    16441 attaaaaatt tgccgcaaat agtgttgttg aatattgtcg gcctcgcgct gtttctttcc
    16501 tggtatattc ccgttaatca tggattctgg ttgccgattg atgcggatat tttttatttc
    16561 tttaatcaga aactggtcga aagtaaggcc tttttgtggc tggttgcatt gaccaacaat
    16621 cgcgctttcg acggttgttc tctgctggcg atgggaatgt tgatgctggg tttctggctg
    16681 aaagaaaacg cccctggcag acgacgtatc gtgattatgg gtctggtcat gctattaact
    16741 gcagtggtat taaaccagct gggtcaggca ttaattcctg taaaacgggc cagcccaaca
    16801 ttgactttta ccgatattaa ccgcgtcagc gaactgctct ctgttcccac gaaagatgcc
    16861 tcacgagata gctttcccgg cgatcacggc atgatgctgc ttattttttc ggcattcatg
    16921 tggcgttatt tcggcaaagt tgcaggcctt atcgccctta ttatttttgt ggtttttgca
    16981 tttcccagag taatgattgg cgcacactgg tttactgaca tcattgtcgg ttcgatgacc
    17041 gtgatattga tcggtttgcc ctgggtgttg ctgacgccat taagtgatcg attaatcacc
    17101 ttttttgaca aatcactacc gggaaaaaac aaacatttcc aaaacaaata actcacagta
    17161 attaacatca tcaggcttat ttttatagtg aggataatcc tgatgatgcg caccgtgctt
    17221 tcatccatcg cgcgcaaaaa tcattctcta agtaaatgaa tggattgcat gcgtttcact
    17281 caatcgtact ttaattgacc aatcccgctt attaactttc tgtatcactt tttcttataa
    17341 aaaatcatgc aaaaccgctc gccaagaccg catcaatcgg gtaatctcga actcgttttg
    17401 cctcggcggt agattatcct cacagcatat aattttgtgc gttagtccac agatttggcc
    17461 ttaaggaatt gtttcaacat gcccaggtaa ttagtctcgt gtcgcttggc atttttttat
    17521 aacgatattt gtcgttaagg acttcaaggg aaaacaaaca acatggtcaa atctcaaccg
    17581 attttgagat atatcttgcg cgggattccc gcgattgcag tagcggttct gctttctgca
    17641 tgtagtgcaa ataacaccgc aaagaatatg catcctgaga cacgtgcagt gggtagtgaa
    17701 acatcatcac tgcaagcttc tcaggatgaa tttgaaaacc tggttcgtaa tgtcgacgta
    17761 aaatcgcgaa ttatggatca gtatgctgac tggaaaggcg tacgttatcg tctgggcggc
    17821 agcactaaaa aaggtatcga ttgttctggt ttcgtacagc gtacattccg tgagcaattt
    17881 ggcttagaac ttccgcgttc gacttacgaa cagcaggaaa tgggtaaatc tgtttcccgc
    17941 agtaatttgc gtacgggtga tttagttctg ttccgtgccg gttcaacggg acgccatgtc
    18001 ggtatttata tcggcaacaa tcagtttgtc catgcttcca ccagcagtgg tgttattatt
    18061 tccagcatga atgaaccgta ctggaagaag cgttacaacg aagcacgccg ggttctcagc
    18121 cgcagctaat aaaccgtttg gatgcaatcc cttggctatc ctgacgagtt aactgaaagc
    18181 actgcttagg cagtgctttt ttgttttcat tcatcagaga aaatgatgtt tccgcgtctt
    18241 gatccaggct atagtccggt cattgttatc ttttaaatgt tgtcgtaatt tcaggaaatt
    18301 aacggaatca tgttcatacg cgctcccaat tttggacgta agctcctgct tacctgcatt
    18361 gttgcaggcg taatgattgc gatactggtg agttgccttc agtttttagt ggcctggcat
    18421 aagcacgaag tcaaatacga cacactgatt accgacgtac aaaagtatct cgatacctat
    18481 tttgccgacc tgaaatccac tactgaccgg ctccagccgc tgaccttaga tacctgccag
    18541 caagctaacc ccgaactgac cgcccgcgca gcgtttagca tgaatgtccg aacgtttgtg
    18601 ctggtgaaag ataaaaaaac attctgttca tctgcgaccg gtgagatgga cattccactc
    18661 aatgaattga ttccggcgct cgacattaat aaaaacgtcg atatggcgat cttacccggc
    18721 acgccgatgg tgccgaacaa acccgcaatc gtcatctggt atcgcaaccc tttgctgaaa
    18781 aatagcggcg tctttgccgc tctgaatctc aacctgacgc cttcactctt ttatagttca
    18841 cggcaggaag attacgatgg cgtcgccctc attattggca atactgcgct atctaccttt
    18901 tcttcacgtt tgatgaacgt taacgaatta accgacatgc cagtccgtga aactaaaatt
    18961 gcgggcattc ctctgaccgt tcggctttat gcagatgact ggacatggaa cgatgtgtgg
    19021 tacgcatttt tactgggcgg catgagtgga actgtcgttg gcctgctctg ctattacctg
    19081 atgagcgtac gtatgcgccc cggcagagaa atcatgaccg ccatcaagcg cgaacaattt
    19141 tacgtggcgt atcaaccggt ggtggataca caagctttgc gagtaacggg cctggaagta
    19201 ctgctacgct ggcggcatcc tgtcgcggga gaaattcccc cggatgcctt cattaacttt
    19261 gccgaatcgc aaaagatgat tgtgccgctg actcagcacc tgtttgagtt aattgcccgc
    19321 gatgccgcag aattagaaaa agtgctgccg gtaggcgtca aatttggtat taacattgcg
    19381 ccggaccatc tgcacagcga aagctttaaa gcagatatcc agaaactgct cacttccctg
    19441 cccgcacacc atttccagat tgtgctggaa attaccgagc gcgatatgtt gaaagagcaa
    19501 gaagccacac aactcttcgc ctggctgcac tcggtcggcg tagaaattgc tattgatgac
    19561 ttcggcaccg ggcacagcgc gcttatctat cttgagcgtt ttacgctcga ttatctgaaa
    19621 attgaccgtg gatttatcaa cgccatcggt acggaaacga tcacttcccc cgtacttgac
    19681 gcggtgctga cgctggcgaa acgcctcaat atgctgacgg ttgctgaagg ggtcgaaacg
    19741 ccggaacagg cgcgatggct aagcgaacgc ggcgttaatt tcatgcaagg ctactggatt
    19801 agccgcccgt taccgctgga cgattttgtt cgctggctaa agaaaccgta tacgccgcag
    19861 tggtaaggtg tgcttacgtc ccttattatt catagtgaaa gcatgccgga ttgcggctaa
    19921 tgatgagtaa aaggaaatcc gttgcagatg attgtgcgca tactgctgct gtttatcgct
    19981 ctgttcacct ttggtgtgca ggcgcaggct atcaaggaaa gctatgcctt tgccgtgctg
    20041 ggcgaacccc ggtacgcgtt taatttcaac cattttgatt atgtgaaccc cgccgcgcca
    20101 aaaggtgggc agataacgtt gtcagccctc ggcaccttcg ataatttcaa ccgctatgca
    20161 ctgcgcggca acccgggcgc acgcaccgag cagctgtacg acacgctatt tacgacttcc
    20221 gatgacgaac caggcagtta ttacccgctg attgctgaaa gcgcacgcta tgctgacgat
    20281 tattcctggg tggaggtcgc tattaatccg cgcgcccgtt ttcatgatgg ttcgcccatt
    20341 actgcccgcg atgtagagtt tacttttcaa aaatttatga ccgaaggcgt gccgcaattt
    20401 cgtctggtct acaaaggcac caccgtcaaa gccattgcac cgttaaccgt gcgcattgag
    20461 ttagctaaac ccggcaaaga agatatgctg agtctgtttt cgctgccggt atttccagaa
    20521 aagtactgga aggatcacaa acttagcgac ccgttcgcca cgcctccgct tgccagtggt
    20581 ccgtaccgcg ttacgtcctg gaaaatgggg caaaatattg tctattcccg tgtgaaagat
    20641 tactgggcag caaacttacc ggtaaaccgt ggacgctgga atttcgacac cattcgctac
    20701 gattattacc tcgatgataa tgtcgccttt gaagcgttta aagcaggtgc ctttgatttg
    20761 cgtatggaaa acgacgccaa aaactgggcc acgcgttata ccggtaaaaa tttcgataaa
    20821 aaatacatca tcaaagatga gcaaaagaac gaatcagccc aggatacgcg ttggctggcg
    20881 tttaatatcc aacgtccggt attcagcgat cgccgggtcc gggaagctat cactctcgcc
    20941 tttgactttg aatggatgaa caaggcgttg ttttacaatg cctggagtcg cacgaacagt
    21001 tattttcaga ataccgaata cgcggccaga aattaccccg acgccgcgga gctggtgctt
    21061 ctggcaccaa tgaaaaaaga tctaccgtca gaagtcttca cacaaatcta ccagccgccg
    21121 gtatccaaag gcgatggcta cgatcgtgac aacctgttaa aagccgacaa acttctcaac
    21181 gaagcgggct gggtgctgaa gggtcagcaa cgcgttaatg ccacaacggg tcagccactc
    21241 agctttgaat tattgcttcc cgcaagcagc aatagtcagt gggtattgcc gttccagcac
    21301 agcctgcaac ggctgggtat caacatggac attcgcaagg tggataactc gcaaatcact
    21361 aaccgcatgc gcagtcgcga ctatgacatg atgccgcgcg tatggcgggc gatgccgtgg
    21421 cccagttccg atttacagat ttcctggtca tcggaatata tcaattccac ttataatgcc
    21481 cccggcgtgc aaagcccggt tatcgactcg ctgatcaacc aaattattgc cgcgcaggga
    21541 aataaagaaa aattactgcc gttggggcga gcactggatc gcgtattaac gtggaattat
    21601 tacatgctgc caatgtggta catggcggaa gaccgtctcg cctggtggga taaattctcc
    21661 cagccggccg tgcgccccat ctatagcctc ggtatcgata cctggtggta tgacgtcaat
    21721 aaagcggcca aactgccgtc cgccagcaaa cagggagagt agatgggcgc ttacctgatt
    21781 cgccgtctgt tgctggtgat cccaacatta tgggcgatta tcaccatcaa ctttttcatc
    21841 gtgcaaattg cgcctggcgg tccggtcgac caggccatcg ccgccattga gtttggtaat
    21901 gccggagtat tacccggcgc aggcggtgaa ggtgttcgtg ccagccatgc gcaaacgggt
    21961 gtcggcaata tcagcgacag taattaccgt ggcggacgcg gattagatcc agaagtgatc
    22021 gctgagatca ctcatcgcta cggttttgat aagccgatcc acgaacgtta cttcaaaatg
    22081 ctctgggact acatccgctt tgattttggc gatagcctgt ttcgcagcgc ctcggtgctg
    22141 acgctgatta aagacagtct gccggtttcc atcaccctcg gattgtggag cacgctgatt
    22201 atctatctgg tgtcgattcc gttaggcatt cgcaaagctg tttataatgg gagccgcttt
    22261 gacgtctgga gtagcgcatt tatcatcatc ggctacgcca ttccggcctt tttgtttgcc
    22321 atcctgctga ttgtcttctt cgcgggcggc agctatttcg acctgttccc tctacgcggc
    22381 ctggtttccg ctaactttga ttcgctgccg tggtatcaga aaatcaccga ttatctgtgg
    22441 catatcacgc tgccggtgct ggcgacagtg attggtggct ttgcggcgct gaccatgctg
    22501 acaaaaaact cattccttga tgaagtgcgc aagcaatacg tggtgaccgc gcgtgcgaaa
    22561 ggggtaagtg aaaaaaatat tctctggaaa catgtgttcc gcaacgccat gctgctggtg
    22621 attgccggtt ttccggcgac gtttatcagc atgtttttta ccggctcgct gctgattgag
    22681 gtgatgtttt cactcaatgg tctgggctta ctgggctacg aagcgaccgt ctcgcgcgat
    22741 tatcctgtaa tgtttggtac cttgtatatt ttcaccctga ttggcctgct gctgaatatt
    22801 gtcagtgata tcagctatac gctggttgat ccgcgtattg attttgaggg acgttaatgt
    22861 cgcgactcag ccccgtcaat caggcccgtt gggcgcgttt tcgtcataac cgtcgcggct
    22921 actggtcgtt atggattttc ctcgtcttgt ttggtttgag tttgtgttct gaacttatcg
    22981 ccaacgataa accgttgctg gtgcgttatg acggcagttg gtatttcccg ttattgaaaa
    23041 actacagcga aagcgatttt ggcggcccgc tggcaagtca ggctgattat caggacccgt
    23101 ggctgaaaca acggctggaa aataacggct gggtactgtg ggcaccgatt cgctttggtg
    23161 ctaccagtat caactttgct accgataagc ccttcccttc tccaccctcc cggcaaaact
    23221 ggctgggaac ggatgccaac ggcggcgatg tgctggcacg cattctctat ggcacgcgga
    23281 tctcggttct gtttggcctg atgctgactc tctgttccag cgtgatgggc gtgctggcgg
    23341 gggcgctaca aggttattac ggcggtaaag tcgatctctg gggacaacgc tttattgaag
    23401 tatggtcggg gatgccgacg ctgtttttga ttattatact ttccagcgtc gtacagccta
    23461 acttctggtg gctgctggca attactgtct tgtttggctg gatgagtctg gtcggcgtgg
    23521 tgcgggcgga gtttttacgt actcgtaatt tcgactacat tcgtgcggca caggcgcttg
    23581 gcgtcagcga tcgcagtatc atcctgcgtc atatgttgcc taatgccatg gtcgcgaccc
    23641 tcaccttttt accgtttatt ttatgtagtt cgataaccac cctgacctcg ctcgatttcc
    23701 tcggcttcgg tctaccgctc ggttcaccgt cactcggtga actgctgtta caagggaaaa
    23761 ataaccttca ggccccgtgg cttgggatca ccgccttctt gtcggtggcg atattattgt
    23821 ctttgctgat ctttattggt gaagccgtcc gcgacgcatt tgatcctaat aaggcggtgt
    23881 agcatgacgc aaactctgtt agcgattgaa aatttgtcgg tgggttttcg ccatcagcaa
    23941 accgtacgta cagtagtcaa tgatgtttca ctacagattg aggctggcga aacgctggcg
    24001 ctggtgggtg agtcaggttc aggcaaaagc gttaccgcgc tgtcaatttt acacctgctc
    24061 ccttccccgc cggttgaata tctctccggc gatattcgtt ttcatggcga atcgctgctt
    24121 cacgccagcg atcaaacgtt gcgcggtgta cgcggtaata agatcgccat gatttttcag
    24181 gaaccgatgg tgtcgttaaa tccattgcat accctggaaa aacagcttta tgaagtgctt
    24241 tcactccacc gcgggatgcg tcgggaagcg gctcgtggcg aaattcttaa ctgccttgat
    24301 cgcgttggta tccgccaggc ggcaaaacgg ctgacagatt atccgcatca gctctccggc
    24361 ggcgaacggc agcgggtgat gattgcgatg gcgctgttaa cgcgaccgga attattaatt
    24421 gccgatgaac cgaccaccgc actggacgtc tctgtccagg cgcagatttt acagctgttg
    24481 cgcgaactgc aaggcgagct gaatatgggc atgctgttta ttactcataa cctcagcatt
    24541 gtcagaaaac tggcccaccg cgtggcggta atgcaaaacg gtcgctgtgt cgagcaaaat
    24601 tacgccgcta cgctatttgc atcacccact catccttaca cacaaaagct actcaacagt
    24661 gaaccgtcag gcgatccagt gccgttgcca gaacctgcct caacgttgct ggatgttgaa
    24721 cagcttcagg ttgccttccc cattcgcaaa gggattttga agcgcattgt ggatcataat
    24781 gtggtggtga aaaacatcag ttttacgcta cgagcgggtg aaacactggg tttagtgggc
    24841 gagtccggtt ccgggaaaag tacgacggga ctggcgctgc tgcgactgat taattctcag
    24901 ggcagcatca tctttgacgg tcagccactg caaaatttaa atcgccgcca gctgttacct
    24961 attcgtcatc gcattcaggt ggtatttcag gatccaaact cctcgctcaa cccacgactc
    25021 aacgttttgc agattattga ggaaggctta cgggttcacc agccgacgct ttctgccgca
    25081 caacgcgaac aacaagtgat agccgtgatg catgaagtgg gattagatcc tgaaacacgc
    25141 caccgttatc cggcggagtt ctctggtggt cagcgacaac gtattgcgat tgccagggca
    25201 ttaattctta agccctcgct gatcatactt gatgaaccga catcatcact cgacaaaacg
    25261 gtacaggcgc aaatattgac gctattgaaa tcattgcaac aaaagcatca actggcctat
    25321 ttgtttatca gccacgattt gcacgttgtc cgcgcgttat gtcatcaggt tatcatactg
    25381 cgacaagggg aagtagtgga acaaggaccg tgcgcgcgcg tgtttgccac accgcagcag
    25441 gagtatacgc gtcagctact ggcgttgagc tgacgcttaa aaaggattgt agtttgaaaa
    25501 gggttcggca attgccacac caaaattttt caatcggcat gttgcagcaa actcgtcctg
    25561 gcgatttaca aacaggcacg gctcaccttc acactccagc accgaacatg gaacttcgat
    25621 gtcgcttaac gcctggctta gtttatacat caccgaccat gcattatcac catccgggct
    25681 aagcaattta agcgccacca ggctgttgtc accgcacggt ccattttgcg gaatcggttc
    25741 aaccttcgaa cctgcgaaac cagcagacca gcgatagttc tgcggcagtc gatggacgat
    25801 tgagagttgt aatgaagtca cttattttcc ccggaagcac attcacttca caatttgttt
    25861 acatcaattt taacacatca tcaacaatcc gtctttatac agatcgtaaa gattgatgcc
    25921 tcgcctgcgt ggcctctatg gctctgattt aagtaatatc tgcgggcgtg gtcacgtttg
    25981 cggggctata tgtacccgtt tctgcgatct aactcaacct ttttaactac aatgatgtga
    26041 ctttttacat aaattgattt tacataaaat aaacatatat cgggggaatg atagatttgt
    26101 ggttgacatg catcaacaaa ggaagccttt tagcttcctc gttgtgcaat agatcaccgt
    26161 tttttcggcc gactggcgta cagacagaag agaatggagc tggttgcgca gaatgcaatt
    26221 gaccaaatca tcggccatgc agagttaaag gtcgcaagag aaagcaatgc gccaacaatt
    26281 gcccctatgc caaaacggaa ggttcctgcc agcgaagatg ccgttcccgc catatgggga
    26341 aactcatcaa gaatgaccgc catcgcattg gatgacacca tcgacacgca gcccacaaac
    26401 gccgcaacgc caaccaccag cgaccaaaat cccagcccca gcagcgcact gatgaccatc
    26461 cacgctgcca taataaattg tatccacaac cccgagcgga acatatttaa cgcgccaatg
    26521 cggcggacga agcggctgtt aaagatggtc atcacgaaca gaaaaacaat gtttagcgca
    26581 aagtaataac caaagttttc cggcgcgacg tggttaattt caatataaac aaacggtccg
    26641 gcgcttaaga atgagaacat cccggcaaag ctgaaaccac tggcaagcat gtagctcagg
    26701 acacgtttat ggcggaacag cgccgcaaag ttaccaatag tggtacgaat gtgaaatggc
    26761 tgacgacgct ccggtggtaa ggtttcttta atcaggaaga aaatcattgc cgaagccaga
    26821 atcgccgcta atgccaggat ccagaagatg taatgccagc tcagccacac cagcacccag
    26881 ccgccaacta tcggtgccat cagcggtgca atggttgtca ccagcatgac aaacgacatc
    26941 atccgcgaga actcttcttt cgggtaaata tcgcgcatca gggcgttaat gaccacgctg
    27001 gccgcagccg cagccagccc gtggaagaaa cgcatcacaa tcagctgatc gatggtgttt
    27061 gccaacgcac acgccaccgc ggcggcggca aacaccagcg taccgccgag caccaccggc
    27121 ttacgcccga agctgtctgc catcggcccg tagattaact gccccaacgc aaagcccaga
    27181 atataagtac tgagggtcat ctgcgtactg cccgccggta cgccaaactg cgctgaaatt
    27241 accggtagcg cgggcagata catatcaatc gacagcggca tcaacatggc cagcaggcca
    27301 aggataaaaa caatagcaaa cgacgaatgc tgtcgggtgg tcacaacggg ctcctgaaag
    27361 tcattgaaaa gttagacgac gctggcaatt tcttcttcag ttaacggacg atattcaccg
    27421 ggggctaaat cagcatccag cgtaataccg ccaatacgtt cacgatgcag ctcaaccacg
    27481 tggttaccca cggcggcgaa catgcgtttc acctgatgat aacgcccttc gctgatggtc
    27541 agacgaacct gcgttggggt aatcacttcc agcaccgcag gcttagtgag atctttttcg
    27601 ttatgcagct gcacgccttt agcaaattgc tctgccgtat cgtcagctac aggtgattcc
    27661 agtgtcacca gataggtctt ctcgcaatga tggcgcggag aagtaatgcg gtgcgaccac
    27721 tgaccatcat cagtcatcag caccagaccg gtggtatcaa tatccaaccg ccccgccgca
    27781 tgcagtttcc acgctaccgg ttcatcaaga aaatagagca ccgttgggtg atcagggtcg
    27841 tccgtggagc aaacatagcc ctgaggctta ttgagcatga agtaacgtgg accgtgttgc
    27901 tgcgccagcg ggttgccatc gtaagcgaca tcatgttcag gaagcagttt gaacgctgca
    27961 ttacggacga tttcgccatc gacggtgaca cgattgccgc ggatttcacg cccggcaata
    28021 gcacggctaa cgccgagttg ctgtgcgata aatttatcaa gtcgcatgtg tgtgattttg
    28081 cctgtaaaaa cggaggtcgg gcattgaccc gaaaatctga actgttgtct gcccagtata
    28141 gcggtctaat aacatccctc aagggaaaaa gatccatggc atactattag cagaataatc
    28201 tacctacgcg agaccatgat ttttacactt cgcccatatc agcaagaagc cgtggatgcc
    28261 acgctcaacc attttcgtcg tcataaaacc cctgccgtta tcgtgctgcc caccggcgca
    28321 ggtaaaagcc tggtgatagc ggaactggca cggctggctc gtggtcgcgt gctggtgctg
    28381 gcacacgtta aagaactggt ggcgcaaaac catgcaaagt atcaggcgct ggggctggaa
    28441 gccgatattt ttgccgccgg gctaaagcgc aaagagagcc acgttaaagt ggtatttggc
    28501 agcgtgcagt ctgtcgcccg taatcttgat gcctttcagg gtgaattttc gctgttgatt
    28561 gtcgatgaat gtcaccgtat tggtgacgat gaagagagcc agtatcagca aatcctcact
    28621 cacctgacaa aagtgaatcc ccacttacgc ctgctggggc tgactgccac gccttttcga
    28681 ttgggcaaag gctggatcta ccagtttcat tatcacggca tggtacgcgg cgatgagaaa
    28741 gcccttttcc gtgactgcat ttatgagctg ccgctgcgtt atatgattaa acacggctat
    28801 ctgacgccgc cagaacgact ggatatgcca gtagtgcaat acgatttcag ccgcttgcag
    28861 gcacagagta acgggctgtt cagcgaagcc gatctcaacc gtgagctgaa aaaacaacaa
    28921 cgtattaccc cgcacatcat cagccagatt atggagtttg ctgcaatgcg caaaggggtg
    28981 atgatttttg ccgcgacggt tgaacacgca aaagagattg tgggattact gcctgccgaa
    29041 gatgcagcac tgattactgg cgacaccccc ggcgctgagc gcgatgtgtt aattgaaaat
    29101 tttaaagccc agcgttttcg ctatctggtc aacgtcgcgg tactgaccac cggatttgac
    29161 gccccgcacg tcgatcttat cgccattctg cgccctaccg aatcagtgag tctttaccaa
    29221 caaattgtcg ggcgcggtct gcgtctcgct ccgggcaaga ctgattgctt aattcttgat
    29281 tatgcgggta atcctcacga tctctacgcg ccggaagttg gtacaccaaa aggcaaaagt
    29341 gacaacgttc cggtacaggt tttctgccct gcctgcggtt ttgccaacac cttttggggg
    29401 aaaacgaccg ccgacgggac attgattgaa cactttggtc gtcgctgtca gggatggttt
    29461 gaagatgacg acggtcatcg cgaacaatgt gacttccgtt tccgttttaa aaattgcccg
    29521 caatgtaacg cggaaaacga tattgccgcc cgccgctgcc gcgaatgtga caccgtactg
    29581 gttgatccgg acgatatgtt aaaagcggcg ctacgactga aagacgcgct ggtattacgc
    29641 tgtagcggca tgtctttgca acatgggcac gacgagaaag gcgaatggtt gaaaatcacc
    29701 tattacgatg aagacggcgc ggatgtgagt gagcgtttcc gtctgcaaac acctgcccag
    29761 cgtaccgcct tcgagcagct ttttatccgc ccgcatacgc gcacaccggg catcccgctg
    29821 cgctggatca ccgccgccga tatcctcgcc cagcaagcct tattgcgaca cccggatttt
    29881 gtcgtcgccc gcatgaaagg ccagtactgg caggtgcgtg aaaaagtgtt cgattacgaa
    29941 ggtcgttttc gtctggcgca cgaattacgc ggttaatggt agttttgatt gatgtataag
    30001 gcgattgagt atagaatctc gcccgctttt gcatacgcaa agcagatcac ttacctgttg
    30061 ctgggtcgcc tgtagcagga ttaatttaag agagaaagaa atgtttacta tcaacgcaga
    30121 agtacgtaaa gagcagggta agggtgcgag ccgccgcctg cgtgccgcta acaagttccc
    30181 ggcaatcatc tacggtggca aagaagcgcc gctggctatc gagctggatc acgacaaagt
    30241 catgaacatg caagctaaag ctgaattcta cagcgaagtt ctgaccatcg ttgttgacgg
    30301 taaagaaatc aaagttaaag ctcaggacgt acagcgtcac ccgtacaaac cgaagctgca
    30361 gcacatcgac ttcgttcgcg cttaattgct gaataagttg taaaaaaccc cgctccggcg
    30421 gggttttttg tatctgcaga ttatgcctga ttacggtatt gctatttttt gcaggccaga
    30481 taaggcgttc acgccgcatc tggcattcag aacacaaaac cgattaattg ccgccagacg
    30541 tccggcgctg caattggtcg cgcaaattcg gcggcgtgcc tttaatggtc aaggtatcgg
    30601 ttgctggatc ccagaagatg cgttcaccta acagcatcgc atcaaagtta atagtcaagc
    30661 caccgccgct accggcaaac ttcgtcaact gacgcagtgt gctacggtct gccgggaagc
    30721 tctcttccag ttcgtagcct ttttcagccg caaactccgt gaagctcact tcgcttacgc
    30781 ctgccagctc tttcgacagc gatttcagtt cgatctcttc gcctgcctgc agctgctcat
    30841 tacagtagct ataaacctgc tggcgcacgt tctgtcgctc tgctttatcc agttgtgctt
    30901 cggcagtgaa atcatcaacc gcttgcaaca gcccacggtt ttgcgctttc gcgtttaacc
    30961 cttcgctggc cccgaggaaa tccataaaga aatccgccac tttgcgccct actcgccctt
    31021 tcaggaaagt gagatagcgg gtggactctg gattggtttc ccattcggtt aaatcgatac
    31081 gcgcaacaat atccgcatga ttgatatcaa gataatgggt tgggttgatg tcgagatttt
    31141 cgttaacgcg catactgctc aggttgctca gaactgccac cagcaaatac tccaccgcca
    31201 gatagcgata gtggcaaaac agcacgaatc caccgtcagc aaaaggatat ttcgctaatt
    31261 cgtcacgcag gcggccggtt gccgcgcggc taaatgccag gaagtcctct tcgccctgac
    31321 gctgtaagcg cagcgtctgc gccagttcac tctcttcgct aaacaagccg taagctttat
    31381 ttttggcgct atagacccga tgcagttctg ccaccatctc aacgacggtt tctgtcggtt
    31441 ccagcaatga atcgcgcaac accagctcaa ggttctgctc atcacgcttg ataagctggt
    31501 gcagagcaat ctggttgata tccagactca tgataaactc tcctttaaga ccgggcggta
    31561 ttcaaccacc gccggttaag cgacgcaata aaagatggcg gtcattttac agaaggcagc
    31621 gtaacgagaa tgatttaacg cataaaaaag cagaaaaaaa accgttgcta cggtaatatg
    31681 ttgccctttc atcaactaac tgatttcgat ttatgccaca aatttcccgc tacagtgatg
    31741 aacaggttga acaattgctc gcagagctgc tcaacgtact ggaaaaacat aaggctccga
    31801 ccgacctttc cctgatggtg ttaggcaaca tggtcactaa ccttatcaac accagcattg
    31861 ccccggccca acgccaggca attgccaact cttttgcccg cgccttacag tcctctatca
    31921 acgaagacaa agcgcactaa gggaaacaga taacaggtta tggtaactca tcgtcagcgc
    31981 taccgtgaaa aagtctccca gatggtcagt tgggggcact ggtttgcact gttcaatatt
    32041 ctgctttcgc tcgtcattgg cagccgttac ctgtttatcg ccgactggcc gacaacgctt
    32101 gctggtcgca tttattccta cgtaagcatt atcggccatt tcagcttcct ggtgttcgcc
    32161 acctacttgc tgatcctctt cccgctgacc tttatcgtcg gctcccagag gctgatgagg
    32221 tttttgtccg tcattctggc aacggcggga atgacgctat tactgatcga tagcgaagtc
    32281 tttactcgtt tccatctcca tcttaatccc atcgtctggc aactggttat caacccagac
    32341 gaaaatgaga tggcgcgcga ctggcagctg atgttcatca gcgtgccggt tattttattg
    32401 cttgaactgg tgtttgcgac gtggagctgg caaaagctgc gcagcctgac gcgtcgtcga
    32461 cgcttcgcgc gcccgctggc cgcattctta tttatcgcct ttatcgcctc gcatgtggtg
    32521 tatatctggg ccgatgccaa cttctatcgc ccgatcacca tgcagcgcgc taacctgccg
    32581 ctttcgtacc cgatgacggc gcgacgtttt cttgagaagc atggtctgct tgatgcgcag
    32641 gagtatcaac gccgtcttat tgagcaaggt aatccagacg ccgtttccgt tcagtatccg
    32701 ttaagcgaac tgcgctatcg cgatatgggc accgggcaga atgtgctgtt gattactgtc
    32761 gatggcctga actactcacg cttcgagaag cagatgcctg cgctggcagg ttttgctgag
    32821 caaaatattt cgttcacgcg ccatatgagc tccggcaaca ctacagacaa cggcatcttt
    32881 ggcctgttct atggcatctc gccgagctat atggacggca ttctgtcgac ccgtacgcct
    32941 gcggcattaa ttactgcgct taatcagcaa ggctatcagc tggggttatt ctcatcagat
    33001 ggctttacca gcccgctgta tcgccaggca ttgttgtcag atttctcgat gccgagcgta
    33061 cgcacccaat ccgacgagca gaccgccacg cagtggatca actggctggg acgctacgca
    33121 caagaagata accgctggtt ctcgtgggtt tctttcaatg gtactaacat tgacgacagc
    33181 aatcagcagg catttgcacg gaaatatagc cgggcggcag gcaatgtcga tgaccagatc
    33241 aaccgcgtgc tcaatgcact gcgtgattct ggcaaactgg acaatacggt ggtgattatc
    33301 actgccggtc ggggtattcc actgagcgaa gaggaagaaa cctttgactg gtcccacggt
    33361 catctgcagg tgccattagt gattcactgg ccaggcacgc cggcgcagcg tattaatgct
    33421 ctgactgatc ataccgatct gatgacgacg ctgatgcaac gcctgctaca tgtcagcaca
    33481 cctgccagcg aatattcgca aggtcaggat ttgttcaacc ctcaacgccg tcattactgg
    33541 gttaccgcag cggataacga tacgctggca attaccaccc cgaaaaagac gctggtactg
    33601 aacaataacg gtaaataccg cacttacaac ttacgtggtg aaagagtgaa agatgaaaaa
    33661 ccacagttaa gtttgttatt gcaagtgctg acagacgaga agcgttttat cgctaactga
    33721 ttaattataa atcagttagc gaaatatctt acttgcaatc ggtgtggaaa acggtagtat
    33781 tagcagccac gagtcggcac gtagcgcagc ctggtagcgc accgtcatgg ggtgtcgggg
    33841 gtcggaggtt caaatcctct cgtgccgacc aaaaatccca agaaaaaacc aacccttacg
    33901 gttggttttt ttatatctgc aattaattcg ataaacagac cgtgacacat cacagcctgt
    33961 ttattttctg ttatcagaac gtccagacca cacccgcctg agtattccac ggcgattcta
    34021 cccctgcgcc attgccatag ctgactgaca aatgaccgct taacgtcggg gtaaacgatg
    34081 accttatacc agcctgataa acgccactgg ttccagccac atcattatta aatttgccat
    34141 cgtcattaac tttcacctgg ttagaatcgg cgtattcctg acgcacggcc gctttcagcc
    34201 agggttccag cgtcgtaccg ttttgcaggt ccatgtgata gcttaccgcc gttcccgctt
    34261 cagcgcgtaa tatccgggta tttcccacat ccgcgcgcat gccgtttgat aacgtgtagt
    34321 cctgaccatc tgtggtaaag ccggtaaagg ccagataggg tctaacactc cacaatccgt
    34381 caacccaacg gaacccgctc tcaacatgag cacccgcgcc gttactattg taatcgccaa
    34441 acgctgttgc cccattactc atcttgccat ggatggtgtt ggcaaaacgg tcaactttca
    34501 ccaccccatc aacataggca ccgttctgat gctcccaacc ggcataagcc cccagggtat
    34561 agctatcgat attacctttg ccgccgcgat caaaaccaat atcagaatga gagtaaccaa
    34621 agatcaagcc gcgaattgta ctgctttctt cacgggagaa acggctatcg ataccgagcg
    34681 tcaggcccgt caatgtttgc tcaaaaccag ctcccgcatc agtggtcacg ttgttgcggg
    34741 tgttaattgc cgaactccac atcgccgtat cgtaactaac gccttttacg ctaccaagac
    34801 gctcacgcac ggtgtccagt tctgcatcaa ataccagcgg ttgtgcggcc gccatattca
    34861 gcacatcagt ggttgaaggg gtaatttgcg cgcgattctc tgccagactc cagctatggt
    34921 tgccattatc cagcaaggta tattcatacg taccgatatc aacaacgcct ccggcattgc
    34981 ccaacgtaaa tgcagcatca ccgccgcccg ttgttaccag tgtaaggcta tctcctgctg
    35041 ccgggctggc accggtgtcc gtcacgaata ttttgaaatc acctgttgcc tgaccggtga
    35101 cgttgagctg atcgctctga tgattagcca tatcggtacg catataaaaa ttgccgtttc
    35161 ccgacagggt attggtggtc aacgtaatga aattttccgc acttgccgtc actgatgaac
    35221 gagtcactgg ctcatccatc ataatcacat ttgcgtcaga catcgcaagg ttggctaagt
    35281 tgaggagggt gttttggttc gtcgtagtga tatcggcaat gatggtccat acgctatttt
    35341 cgagcgaaac gtccgctttg ctggtatcca cggcaccatg cgttctaaaa gaagcgccct
    35401 cagaaaccac taccttaccc accaacattg cgggtgcata atttatttgc ggcttcatga
    35461 cctcaagaat gccatcattc cctctgactg aaacgttaac cattgtgcca gcccagacgt
    35521 tagcgcggcc attgttgata accatatttt cagagatggc ttttgaggaa tacgtgatac
    35581 ttccattctg atatgatcga ccgagatcat ataccgcatt tgcctgcact ttcgtaccag
    35641 tatcctttcc cagcgattgc atagtggcat gcttatcaag gatagtatca atggcctgcg
    35701 tgtcctccat aacaatgagc ccggaaccat catccagttc ataatttttt gacacaccat
    35761 cttttatact aaattggcct ttactgtttg gaccactcac ttccagcgca ttcgttgaga
    35821 caattaattt tccgcctgct tttttatcaa cgccagttac agtcccgcca tccataacct
    35881 ccagtaagcc gccactatct acagtggtat tataagcgaa gtcattttct tcaactcgca
    35941 aacttccgcc gttttccaac aacatattat tagcaatacc attcttgata tcgaactgac
    36001 cgagacggtt tgttccgaat acctccatgg cccgcgtggt tgttttaata gcaccgcctg
    36061 ctttctgatc taccgcaaat gcaaatcccc cctctttaac ctccagtagt cctccctttt
    36121 cgatagcgac aaagacggcc ccccatcttt ttcaacgatt aagcgcccgc ctttaatcgt
    36181 ggtatcattc gctgcgccat aaacctgtag cacaccatta ttgagcgtag tctggtttgc
    36241 cgcgccaccc atttgaacaa tttgataacc gtcatttaat actgagtatt ctgcggcgcc
    36301 attcatttca atgtactgat accctccgtt aatttcagta ttattactta caccaaattc
    36361 ttttatatgc tgttctccgc caggattgat tttcgtatta ttggcggtcc cataaaccag
    36421 ctggatatct ttttccagga caacaccatc aactgtctca ccatactcaa cagttgatgc
    36481 caatgctatg ggtgaatata acgctgtagc caccagaaca gatattgcgg aacgacaaag
    36541 agaaacagaa ccagattgat gcattgagct ttcatcctat gaaattaatt gctgttaaaa
    36601 gcattgggta cagaaaatac ccatagctcc atacccggag tcagttttta aaaactgttt
    36661 aaagaaatgc acaagtattg tgattgattt tttagttgtt tttcttgatg agaagctgat
    36721 gcaaaattcc gtctttataa tgaaaatgat gccaaagcga acgacaaggt tgtagttttc
    36781 actacatgtc catacataaa atggggtaac attcacgcgc ctggtagcgt taccaacgct
    36841 acgctcaaac ataatgattc taataaaacc tcaggagact actatgcctg aagcaacgcc
    36901 ttttcaggtg atgattgtgg atgatcatcc acttatgcga cgcggtgttc gtcagttact
    36961 ggagcttgat cctggctttg aagtggtcgc cgaagcgggc gacggcgcga gcgctatcga
    37021 tctggcgaat agactggata tcgacgtgat cttgctggat ctcaatatga aaggtatgag
    37081 tggcctggat actctcaatg ccttgcgcag ggatggcgtt accgcgcaaa ttattatcct
    37141 gaccgtatcc gatgcctcca gcgatgtctt tgcgctgata gacgcaggcg cagacggtta
    37201 tctgttgaaa gacagcgacc cggaagtatt gctggaagcg attcgtgccg gagcgaaagg
    37261 cagcaaagtc tttagcgaac gcgtcaatca gtacttacgt gaacgtgaaa tgtttggcgc
    37321 ggaagaagat cccttcagcg tgctgacgga gcgcgagctg gatgttctgc acgagctggc
    37381 acaggggctg tcaaataaac agattgcctc ggtgttgaat atttccgagc agacagtaaa
    37441 agtacatatt cgcaatctgc tgcgtaaact caatgtccgc tcacgcgtgg cggccaccat
    37501 tctgttcctg caacaacgcg gggcacaata aaaatagccc gatggattta tcatcgggct
    37561 gagatttatg acaaacgcaa aactgcctga tgcgctacgc ttatcaggcc tacgtggatc
    37621 gatcaattta ttgaatttac acaattttgt aggccggata aggcgttcac gccgcatccg
    37681 gcataaacta agcgcacttt gtcaacagtc tagcccgatg gcatcaccat cgggcctctt
    37741 tttatttact ctcctgcggc gacaaatgtt gcatcgcctg cgcgatacta cgttcaatca
    37801 ccgcacggcg agtatcgttg gcaggtaaga gtttcaacat catctcccac gcggcaacgg
    37861 cttcgccaaa tcgctgctgc tcaaaggcat taaacgcata catgcttagc acacggatat
    37921 tgctatggtc cgttctcacc agctgacgta gcagttcacc gccgaggcgg ttgtcgttgg
    37981 gatcagatga acgagtcaac gcttcagcgt atcccagtgc agcatcactg tttttcggat
    38041 cgaggcgata cgcagtggcg tatgcatcgg tggcgatact ggcgttaccc agcgccatgc
    38101 caacgcggcc caacataatc cagccttcta tatctcccgg atttttttgc agttgagtac
    38161 gcatccccag cgcaagacgc gacatctctt cttcgttgag cggatcggct ttcggatcca
    38221 gcgccctgtc cagcaacgcc ggagcctgtg ccgtggcctg ctgccagatt ttcacctgct
    38281 gataattgcc agtctggtag tagctgacgc cagccacaat taacgccacc acaatacccg
    38341 gcagataaac aacatatccg gcacgcttac cttccggcac gctttgttca ggaaacgctt
    38401 ccggcaccac gcgtacccga cgccgcgagc gggcgtatat gacccaaccg ccaatgccaa
    38461 tagccactac tggcagcacc cacagcagca cggtcagcgg cgttaacggc ggatcgtaag
    38521 tgacgaagtt gccgtaacgc gccaccatat aatcgacaat ctctttttta cttttacctt
    38581 cctgcatcag ttcatacact ttctgacgca ggtcggtggc aatcatcgag ttggaatcgg
    38641 caatgctgtt gttctggcat ttcgggcagc gcagttcttc agtgagctga cggaactgtt
    38701 gttcctgtgc ttcatcttta aactgcaaca catcgatggt cgccagcgct gagccggaga
    38761 tcatcagcat cagcacgccc aataaaaacc tcattgtgcg gcctccttac tgtatttctc
    38821 ccacagcggc ttgatctctt cttcccagac gcgaggattc agatcgcccg catggcgata
    38881 gcgaatgatg ccgttgccgt caataagaaa cgtttctggc gcgccataga caccgagatc
    38941 cagccctaac atgccatcgc catcaaacag gcttagcgcg taaggattgc ccagctcttt
    39001 cagccagctg attgccttct ggcgatcgtc tttatagttc atgccgacca cgcggatgcc
    39061 ctgcgcagaa agctgattca gatattgatg ttccgcacgg caggtcggac accaggtcgc
    39121 ccagacgtta agcagtactg gtttgccctg agtcagcaca tccgcctgat aaaactgccc
    39181 cggattgtcc agtgattcga gacgaaactt cggcacaggc ttgccaatga gcgccgattc
    39241 cagattggtc ggatcatccc cttcggcatt acgcgccagc tgccacagca gcgccgcggc
    39301 aatcgccagg aagataatca acggaattaa caatactttg cgcttcatac ggcctccggc
    39361 gcagtttttt gcggactcac gcgcttacga tagcgaggat caaacagaca cagcagtccg
    39421 cccaacgcca tcatcagccc gcccgcccaa atccagcgaa caaatggttt gtagtaaaga
    39481 cgcacggccc acgcgccgtt ttccagctct tcaccgaggg ccgcgtacag gtcacgcgtg
    39541 atgccgccgt caattgccgc ttcggtcatc atcgacccgg cagtgttgta ataacgtttt
    39601 tccgcataca gcaccgtttc cggcttgcca tcgcgcgtta cgccgatagt cgccacaccg
    39661 ccacgccagt tcgggccagt cacctctttg acatcacgga aggtgaagcg atattcatga
    39721 atatcgacgc tatcgccgga cttcatgcgc acatcacgct caacgctata gttctggcta
    39781 aaggcaatgc caacaattgt cactgccagc ccaaggtgag ccgccaccat cccccaataa
    39841 ctgaaggtgg ttttcgtgcc gcgtgaaata cgtagcgcag cttccgcaat tgccagcacc
    39901 gcaatccagc aggccattgc caggccgagc accgtcatcg ccacaacttt gctttcgaac
    39961 agccacggca acagcagcga cagcaccagc gtagagatga aggcgataat caataaattg
    40021 cggatcttac gcgggcgatc ccgcccccag cgcaccagag gaccgacacc aagcagtagc
    40081 gcaaacggca ccatcagcca ggtaaacatg gtgttgaaga acggttcgcc aatcgaaata
    40141 ctgcccagtc ccagttgctt atgcaccaac ggcagcagcg tccccagcaa caccaccagc
    40201 atcgcagcga ccagcaaaac attgttcgct aacagcaaag attcccgcga ccacagcgca
    40261 ttgtttacgc gtgagcgaac tttgtgtcca cgcgcggcaa acagcagcag cgaaccgcca
    40321 atcaccagca ccataaaggc gaggataaac ataccgcgcg ccggatcaga cgcaaacgcg
    40381 tgtaccgata ccagcacgcc ggaacgcacg aggaaagtcc ccaacagaca caacgagaag
    40441 gcactgattg ccagcagtaa tgtccacgct ttgaagctgg cgcgttgttc agtgaccgcc
    40501 agtgagtgca tcagcgcagt ccccaccagc cacggcataa acgaggcgtt ttctaccgga
    40561 tcccagaacc accagccacc ccagccgagt tcgtaatagg cccatgcgga accgagcacg
    40621 atgccgagcg tcaggaagat ccacgctgcc agcgtccacg gacgagtaaa acgcgcataa
    40681 gtgctgtcca gacgcccgct cagcaaagaa gcaatggcaa aagcaaacgc caccgagaaa
    40741 cccacgtacc ccatataaag cagaggcgga tggaagatca gccccggatc ctgcaatagc
    40801 gggttaagat cgcgaccttc aatcgggaag ttcggcaacg tgcgagagaa cgggttagag
    40861 gtaaagagaa tgaacagcaa aaagccgaca ctgaccatcc ccattatcgc cagtacacgg
    40921 gccacaatat ccagcggaat acgctgacta aaaatcgcca ccgcaaaggt ccagccgctc
    40981 atcagcagca cccacagcag tagcgagcct tcatgcgcgc cccaggtagc cgccacgcga
    41041 taccacaccg gaagctgggt attggagttg ctggcaacat aggtgacggt gaagtcgttg
    41101 accacgaaag cattgaccag caccagaaat gcgccagcca cagacataaa cagcagccag
    41161 gcaaacaagc gggaagacgc catcatgcgc gcatctccgc gcgccacgcc ccatagcgga
    41221 tacacggaca gcagcagcgc aattcccagc gccaggcaca gcagtccgtt accaatttct
    41281 ggcatcatga tgctgggtcc ttataaacac tcgccgggcg acggtggtta gcttccatcg
    41341 ctttctcaac ttctggcggc gtatagtttt catcgtgttt cgccagcact tctttcgcga
    41401 ggatatgatt gcctttttcc agttcgccct gcaccacaac gccctgccct tcacggaaca
    41461 gatccggcaa aatgccttcg taagagacat ccactgagcc ttcagcatcg taaatggtga
    41521 aggtcacttt cagcgaattg ggatcgcgct gcacactacc cggcatcacc atcccgccaa
    41581 cgcgcagacg ctgaccgact tccggcattt gctgagtttc acgcttgccg tagagaattt
    41641 cccccggcgt ataaaagaga tcgatattcg agcgcagcgc atatagcacc agaccgatag
    41701 tcagcgccag ccctgccaac acggcacagg caatccacaa gcggttttta cggcgaatat
    41761 tcatgcagcc tcctgctgtt gcgcagcacg taaacgcgcc tcacgcgccc gctgttgcgc
    41821 cacgccacgc agaattgcgc gatgttgcat caccgagtgc acgaccaaaa ccaccagcgg
    41881 aataacggtc atcaccaccg ccagccagac aaaaaaggcg taaccgccca ttgcgaaaaa
    41941 ttcattccag gaagcaaatg caggggtcat ttacggcctc ttttcagtat cagttcactc
    42001 acccacggac ggcgtttttc catcagcaaa atcaaattac gcatccgcat cagcgtcagc
    42061 gtggcagaca ggagcaggaa gccaaaaatc gaccagcgca gcggcgaacg catcgccgga
    42121 tcgatacttt gctgcatccg cgttgatccc tgatgcaggg tgttccacca ctccacggag
    42181 taatgaataa tcggcagatt caccacgcca atcagcacca ggatacctgc cgcacggccc
    42241 gccagacggc ggtcgtcgaa ggcgtgccac agggcaatca cacccacata caaaaacagc
    42301 agcaccagtt cagaagtcag acgtgcatcc catacccacc aggtgcccca catcggtttt
    42361 ccccatgcag agccggtaac cagggcaata aaggtaaaca cggcaccaat gggggccatc
    42421 gccgccaccg ccaggttggc cattttcatc tgccagacaa ggccaataaa cgctgccact
    42481 gccattgatg cataaatgcc catcgaccag atcgccgcag gcacatgcag gtagataatg
    42541 cggtagctat ttccctgctg ataatcagcc ggagcaaagc cgaatcccca gatccagccg
    42601 acggtaagca cgaccacact ggcaattgcc agccacggta taaaccagcc acagatttga
    42661 tacagccgtg gtgggatcgc cagttgatgc agtgttttcc acatagtttc gataccagac
    42721 tcgaacaaaa atcagtaatc cagcgttatt gaatgctgat tcgtaacgct gccgccgtcg
    42781 caaaaggact taatgtcgcg gtgcctgcca gcaacgcgcc taaaattgcc agatacccgt
    42841 caacgggcaa atgcatagaa gccgcgtcca tcgcggcggt ggcaaagatg agtaatggga
    42901 tagtcagcgg taacaccagt atgctgagca gcacaccacc gcgcttaagt cccactgtca
    42961 gcgccacgcc cggtgcaccg agaaagccaa gcgtaggcgt tcccagcagc agcgtcagcg
    43021 ccatcacttg ccagccataa acatccattc ccagtagcat tgctaccagt ggcgaaagga
    43081 tgagtaacgg cagaccggtt accatccagt gcgccatcac cttcgccagc acaacggcgg
    43141 gcaagggtaa cggcaacaac atcaattgtt caagactgcc gtcctgcaaa tcgtcacgga
    43201 acagtcgttc cagcgccagc aaggatgaaa gcagcgcagc aacccagata atgcccggtg
    43261 caatacgcgc cagcagttgc ggctccggac cgatactgag cggaaaaagg gtaattacaa
    43321 tcaggaagaa ccacagcggg ttgacgattt cggcgctatg gcgaaacgct acacgcagct
    43381 caagacggaa aatgcgccag aacatcatgc ggccctcgtt tgcgtcagtg aaatgcggcg
    43441 aattttactt tcagcaacgt tgagcggctg gtgggtagtc agaatcacaa tccccccctg
    43501 ctccgtatgc tgcgccatac gctgggtcag acgatcgaca ccgttaacgt caatcgcggt
    43561 aaaaggctcg tcgaggatcc ataacgtggc acgggtcagc cacagacgcg ctaaagcgac
    43621 gcggcgttgt tgcccggccg agagctgatt tacaggaata tcttcgaatc cggcaagccc
    43681 ggcctgcgcc agggcttcca gacattgtgc ggtatcgcca tcgcgatgat aaaagtgcag
    43741 attttctaac gccgtcagcc gggttttgat ccccggctga tggcctatcc ataacaggtt
    43801 ttgatggtag ctgtcgcgta cctgatgcaa gggctgccct tgccagagaa cctcgcctgc
    43861 gtcagggcga gacaaccccg tcagcaaacg gagaagcgtt gtcttccccg cgccgttgct
    43921 accggtgatt tgtacccact ctcctgcgtt cagcgtaaat gacaagccac taaataaggt
    43981 tcgttcatcc cgctcacaaa gtaactctct ggcttcaagc atacccacgc aataaccctg
    44041 ttaaaaacct ggctcgactt cacgcatatc gggcagcttg tgcgctatcc ctttatggca
    44101 atcaatacag gtttgcccat ctttcaccgc ctggtcatgc atcttcgcgg caaccgattt
    44161 ctgggcggtt gtatccatat actcgaagtt gtgacagtta cggcactcct gcgagttatt
    44221 gtccttcatg cgccgccact cattctgtgc catcgtcaga cgatgagctt caaatttctg
    44281 cggcgtgtca ataacgccaa aaattttacc atacagctct ttacttgctt tgagcttgcg
    44341 tatcatcttc ggcacaaact cgtgcggaac gtgacaatcc ggacaggtcg cacggacgcc
    44401 gctacggttg ttgtagtgca cggaatccat gtattcctga tacaccgtgt tgcgcatttc
    44461 gtggcagcta atgcagaact cttcggtatt ggctttttcc atcccggtgt taaagccacc
    44521 ccagaagacg atgccgccaa caaaaccgat caacagcagc gtccccagcg ccagacggct
    44581 gggggtacgc caccatttcc acaggcgctt aatcagacca ggcttacggt cagaatttcc
    44641 cataataacc tcttatttcc cgtaaccttt tgatggggta aaggtattcc ccacgattgg
    44701 cgcggtatcg gcctgcggta cgtgacattg cagacagaaa taacgacgcg gagccacttc
    44761 cgcgcccact ttgccgtcgc tgtccataaa gtgagtagga ctgatacgcg gcgcgccagt
    44821 ggtgcgatag ctttcgacac cgtggcactg caagcagcga ttggtattgg tcgttacctg
    44881 ataaccttca acgctatgcg ggatcattgg cggctgattc acatagttca gcggcatccg
    44941 atcctgctct tttggcatcc gaatggcccc ttcctgtgtc ccggatactt ccggcgactg
    45001 gctaaaatcg acgccattag ccgcccaaac cgcgccgctt accaccaggg ccagcatcgc
    45061 cgtccattga cacagcgctt tcttcaggtc atggcttttc atgatttcgc tcccgaactc
    45121 catcgtgtag ttattgtaaa tacatcctca gaacagacat ccacgcagcg accgcacgtc
    45181 atgcaatcgc ggctggtgac ctgcaccggg ctttgttcat ccagcaccgg ggcacgtagc
    45241 acatgcggtt ccgggcaaac atgaaaacaa tccatacagc ggttacattt ctgccgatcg
    45301 gtggccgcaa cggtaatcac acctttgcta cccagcacgc catacagcgc gccaaccgga
    45361 caaatgtgcc cgcaccagcc gtgttcaacg accagtagat caaataaaaa cagcgcgaga
    45421 ataagcagcg cgccgctgcc gaagcccatt accaggctac gccccatcag agaaacgggg
    45481 ttgatccatt cccaaatgag cgtgccagtt aaggctgatc ccaccagaat gaccaccaac
    45541 agcacgtagc gaatgtggcg agggatcgtc gcagactgat tgaggtcaaa gcgcctgcgt
    45601 aaccagttcg ctaagtcggt aatcgggttc agcgggcaga cccagctgca aaataatcgc
    45661 tttcccgcca gggcgtagag cacggtgata atcaccgcac cggtcaacgc caccgtggca
    45721 ggcagatgac cactggcaag actttgcagc gtcatcagcg gatcggtcag cggaacggtg
    45781 tcgaataaca ggctactgct gtagttgccg tgcaagatcc acacaccaaa ccatggaccg
    45841 ctcaaaaaca tccccagcac gaagaactga caaaggcgac gtaacaccag ccaacggtga
    45901 ctgcgccacc agcctttttt ctccagcgcc tcgcgcccgg cgtcacgttt acgatttgcc
    45961 attgttcccc tccagccagc cgaagcggta atggtgacct aactcccctt tcgccagtga
    46021 cagcggtaac accttgattg ccggttgttc cagcacgcat actttttcgc acttaccgca
    46081 accggtacag gcgtcgctgt gaaccgtcgg cagaaagcgg gcgtgcttac cggtacgcgt
    46141 gttgcgctcc agctccaggg tgatggcctc atcaattttc gggcattcgc gataacaaac
    46201 atcgcagcgc agcccctgaa agttgagaca gttttcctgg tccaccagta ccgccagccc
    46261 catccgcgcg tcgtcgatcg attcaatctc acgatccagc gcaccgcttg ggcacacttt
    46321 ggcgcacgga atgtcctcac acatttcgca aggaatatcc cgtgcgacaa aatatggcgt
    46381 gcccgccgac agaccagagg ccagcgtcgc cagttttaag gtgtcgtaag ggcaagcctg
    46441 aacacactga ccgcaacgca cacaggcact ggcaaaggcg ttctcgttta tggctccggg
    46501 cgggcgcaac cgcacgccag atgcgcgtgc ggtttgctgt tgtaacccca gcgccacacc
    46561 cacggcagcc agcccgcctg ctgtgcgaac gacatcgcgc agaaagcggc ggcgaccatt
    46621 ttgaggtttc gctgaccggg acataatggc ttacaccttc tccagtttga ccgcgcactt
    46681 cttgaagtcc gtctctttcg agagcggatc ggtcgcatcc agcgtcagtt tgttaaccaa
    46741 ctgtgcggcg tcgaagaacg gcatgtacac caggccctgt ggcggacggt tacgaccgcg
    46801 cgtttcaaca atcgagatca cttcgccacg gcgagaaacc actttcactt tgtcgccacg
    46861 gcgcagatcg cgcgctttcg catccagcgg gtgaataaac aggaccgctt ccgggaaggc
    46921 gcggtgcagt tctggtacac ggcgagtcat actgccggtg tgccagtgct ccagaacgcg
    46981 tccggtagag agccacaggt cgtactcttc atccggtgct tccgccgccg gttcgaatgg
    47041 cagtgcgaag atcaccgctt tgccatccgg tttaccgtag aacttatagc cttcgcccgc
    47101 tttcacgtac gggtcgttac cttcgctgta acgccactgc gtttctttac cgttcaccac
    47161 cggccagcgc agaccgcgcg ctttgtggta gtcatcgaac ggtgccagat cgtgaccgtg
    47221 accgcgacca aaccatgcgt actcttcgaa cagccctttt tgcagataga agcccagctc
    47281 gcgggattca tcgttcagct gatcttccgc cagttcggat accgggaatt tgctcacttc
    47341 cggtgtggca tacagcactt cgtacagcgt tttgccacgc agttccggtt tcttcgccag
    47401 cagatcttcc ggccatactt cttcagtttt gaagcggcgg gagaactgga ctaactgcca
    47461 gagatccgat ttcgcttcgc ccggtgcctg tacctgttga cgccagaact gagtacggcg
    47521 ttcggcgtta ccgtaagcgc cctctttctc tacccacatt gcggtcggca ggatcaagtc
    47581 ggcggccagc gcactgactg tcggatacgg atcggagacg atgatgaagt tgcgcggatc
    47641 gcgccagccc ggcatacgct cttcattgat gttcggcccg gcctgcatgt tgttggtaca
    47701 catggtccag taaacattca gtttgccgtc tttcagcgca cggtcttgtg ccaccgcgtg
    47761 cagaccgatt ttcgccggaa tggtgccgct cgggatattc cacttcttct cgcagatatc
    47821 acggtgtttc tcgttggtca ccaccatgtc cgcaggcaga cggtgagcaa aggtgcccac
    47881 ttcacgcgca gtaccacacg cagaaggttg cccggtcagg gagaacggac cgcaacccgg
    47941 ctgggaaatt ttgccggtca gcaggtgcag gttgtagacc aggttgttag cccacacgcc
    48001 acgagtatgc tggttgaagc ccatcgtcca gtaggagatg actttcttgt tcggatcggc
    48061 atacagctgc gccagttgtt ctaactggtc tttcggcacg ccggtcattt cggcagtttt
    48121 ttccagcgta tactcggcaa cgaaggcttt gtaatcttca aagctcatcg gttcggaggc
    48181 gtcagaaccc ggattcttcg ctgctttttc cagcggatgg gtcggacgta aaccgtagcc
    48241 gatgtccgtc gcccctttgc gcaggttaac gtgcttgctg aagaagtcct gatttatcgc
    48301 attgttttga atgatatagt tggcgatgta gttcaggatc accaggtcag attgcggcgt
    48361 aaagatgatg ccgttatccg ccagctcgaa gctacgatgc tggtaggtag aaagcaccgc
    48421 cacggtgacg ttctggttag agagacgacg gttagtgatg cgcgaccaga ggatcgggtg
    48481 catttccgcc atgtttgcgc cccacagcac aaacgcgtca gcctgctcga tgtcgtcata
    48541 gcagcccatc ggctcatcca taccaaaggt acgcataaag ccaactactg ccgacgccat
    48601 acagtgacgc gcgttcgggt cgatgttgtt cgaacggaag cccgctttaa acagcttgga
    48661 cgcggcataa ccttcccaga tagtccactg accagaaccg aacataccga tcgattccgg
    48721 ccctttttct ttcagggcgg ttttgaattt ctcttccatc acatcgaagg cctgatccca
    48781 ggtgattggg gtaaattcgc cttctttgtc atatttaccg tttttcatac gcagcagcgg
    48841 ctgcgtcaaa cggtctttac cgtacatgat tttgggcagg aaatagccct taatgcagtt
    48901 caggccacgg ttaaccggtg cgtccgggtc gccctgacag gccaccacac gtccctgctg
    48961 cgttccgacc agaacgccgc aaccagtacc gcagaaacgg cacggcgctt tatcccattt
    49021 gatggcttcc tgctgaccaa caacggcgcg ggcaacgccc ggcacgctga gaccggcagc
    49081 cgccgcagcg gccgcaacgg cgttagcttt cataaagcta cgacgactga gtttcatggt
    49141 gtttcctcac cttgctcttc ctgctggtga taaaccagcg acaccgccag cacgccctct
    49201 acgttgcgta ctgactcaat ggtttggatc agcgtttcgc tgtcttctgc ttccaccacc
    49261 acaatcaact gaccgctcgg cgcgtcgctg acagcaactt cacagccggg aaaggcattc
    49321 agttgggtgc tgatgtctga aattcgttcg cttttggcct gcacgaccag gctgcaaact
    49381 tgccagttag tgtgcatgga gatactccgc agttatggct gataccggac agctggctgc
    49441 acatgctcca catccgttgc aaagttggct attaagttgc ggctggtaga tcccggagag
    49501 cgtcgggcga aagataattg ccattggctc acagctatcc tgacagcggc ggcattcaac
    49561 tgactgatac gccaggcacg cgtccccgat ggtgaactgc aaatcccagg ccctggtgtg
    49621 gcgcggagaa aatagcgatt cggggcaagc ctgcgcgcag gcgtaacaga agctgcactc
    49681 gttatttttg aaattaacgc tcggatagcc gcccgcgccg cgttgcagaa tgttgttttc
    49741 acaagcatta atacaggcgt cgcagcgggt gcaatgggtc agaaaatgag attcatcacc
    49801 ggaccagggc ggacggatac cgttactggc tttgcgccag cgaccagtga gtatgccccg
    49861 acgggatgca tcaatcttca cattgacctt ccatcattaa cgcgctctga aaattgagag
    49921 cgaccaaata aaccgcataa ttaataagcc atttttatag ccgctaagat attaaaggat
    49981 gtgtcaaaga tgcatacccc gatcggggta aaacctgtag caggatcaaa agagtggcgg
    50041 gaagcgtggc aaaaacgggc ttttgctcac atttcaaatg gttataaata tatttatata
    50101 gcgattgatt caccagagat atttctgctg gtttgctctc tcattagaat ttaacactaa
    50161 aagagcaggt aaaattgtct gaatgttctt taagttattc ataaagcaaa ttaataaatc
    50221 tgatgaatat gttaaccttc agcgacatca tcggtgaaaa cctataaatg aagaaggaaa
    50281 gcaaaaaaat gaagaccatt ctacctgcag tattgtttgc cgctttcgct accacttccg
    50341 cctgggcggc agaaagcgtc cagccactgg aaaaaatcgc gccttatcca caagctgaaa
    50401 aagggatgaa gcgtcaggtg attcagttaa ccccgcaaga agatgaatct accctgaaag
    50461 tagaactgtt aatcggtcag acgctggaag tcgattgcaa tttgcatcgt ctcggcggga
    50521 agctggaaaa caaaacgctg gaaggctggg gctatgatta ttatgtcttt gataaagtca
    50581 gttccccggt ttcaacgatg atggcctgcc cggatggcaa gaaagagaag aaatttgtca
    50641 ccgcgtatct gggcgatgct ggaatgctgc gttacaacag caagctgccg atcgtggtgt
    50701 atacgccaga caatgtagat gtgaagtacc gcgtctggaa ggcggaagag aaaattgaca
    50761 acgcggtagt tcgctaaact gccgtgaagt gcggcacccc gtaggtcaga caaggcggtc
    50821 acgccgcatc cgacatccaa cgccc
//
LOCUS       DACAOP010000022        49785 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.022, whole genome shotgun sequence.
ACCESSION   DACAOP010000022 DACAOP010000000
VERSION     DACAOP010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49785
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.022"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..820)
                     /locus_tag="IT892_001466"
     CDS             complement(<1..820)
                     /locus_tag="IT892_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3134697.1"
                     /translation="MSASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNA
                     PGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFEV
                     PLAIACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPID
                     ENEVLDWLGGQFLGVPVSALIMMVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGIN
                     VRRVRILIFTLSGLLAAVTGILLAARLGSGNAGAANGLEFDVIAAVVVGGTALSG"
     gene            complement(845..2356)
                     /locus_tag="IT892_001467"
     CDS             complement(845..2356)
                     /locus_tag="IT892_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAP3134698.1"
                     /translation="MFTATEAVPVAKVVAGNKRYPGVVALDNVNFTLNKGEVRALLGK
                     NGAGKSTLIRMLTGSERPDSGDIWIGETRLEGDEATLTRRAAELGVRAVYQELSLVEG
                     LTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAQKQLVEI
                     ARVMKGEPRVVILDEPTSSLASAEVELVISAVKKMSALGVAVIYVSHRMEEIRRIASC
                     ATVMRDGQVAGDMMLENTSTHHIVSLMLGRDHVDIAPVAPQEIVDQAVLEVRALRHKP
                     KLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLETYEQGEIVINGEKITRPDYGDM
                     LKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISANGVLQWSTIRRLTEEVMQRMT
                     VKAASSETPIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVREL
                     AAEGKSVVFISSEVEELPLVCDRILLLQHGTFSQEFHSPVNVDELMSAILSVH"
     gene            complement(2379..3362)
                     /locus_tag="IT892_001468"
     CDS             complement(2379..3362)
                     /locus_tag="IT892_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP3134699.1"
                     /translation="MPKKMRTTRNLLLMATLLGSALFARAADKEMTIGAIYLDTQGYY
                     AGVRQGVQDAAKDSSVQVQLIETNAQGDISKESTFIDTLVARNVDAIILSAVSENGSS
                     RTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKID
                     QPKIAVINCEAFEVCVQRRKGFEEVLKARVPGAQIVANQEGTVLDKAISVGEKLIIST
                     SDLNAIMGESGGATLGAVKAVRNQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDIS
                     GKKMGNAVFAQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLATHVDGLP"
     gene            complement(3459..6740)
                     /locus_tag="IT892_001469"
     CDS             complement(3459..6740)
                     /locus_tag="IT892_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5107 domain-containing protein"
                     /protein_id="HAP3134700.1"
                     /translation="MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYG
                     VTDTLSEQKTLKSWQAVWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPA
                     LVGLLGPWISGGIEFNWPQHHRPTTFMPVDFTLEAHEDGAQTVWVGETEPMHGLQVMT
                     GFTLRPERAALEIASRVYNGNATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKR
                     AVSAFPIATGTYYKVDYSAGVDISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLH
                     VANHHIAPGKKQWSWGHSEFGQAWDKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEE
                     KRFEQYFLPYHSLGMVQNASRDAVIKLQRSERGIEWGLYAISPLKGYRLAIREIGKCN
                     ALLDDAVALTPATAIQGVLHGINPERLTIELSDADGNIILSYQEHQPQELPLPDVAKA
                     PLAAQDIASTDEAWFIGQHLEQYHHASRSPFDYYLRGVALDPLDYRCNLALAMLEYNR
                     ADFPQAVAYATQALKRAHALNKNPQCGQASLIRASAYERQGQYQQAEEDFWRAVWSGN
                     SKAGGYYGLARLAARNGHFDAGLDFCQQSLRACPTNQEVLCLHNLLLVLSGRQDNARL
                     QREKLLRDYPLNATLWWLNWFDGRSESALAQWRGLCQGRDVNALMTAGQLINWGMPTL
                     AAEMLNALDCQRTLPLYLQASLLPKAERGELVAKAIDVFPQFVRFPNTLEEVAALESI
                     EECWFARHLLACFYYNKRSYNKAIALWQRCVEMSPEFADGWRGLAIHAWNKQHDYELA
                     ARYLDNAYQLAPQDARLLFERDLLDKLSGATPEKRLARLENNLEIALKRDDMTAELLN
                     LWHLTGQADKAADILATRKFHPWEGGEGKITSQFILNQLLRAWQHLDTREPQQASELL
                     HAALHYPENLSEGRLPGQTDNDIWFWQAICANAQGDQTEAMRCLRLAATGDRTINIHS
                     YYNDQPVDYLFWQGMALRLLGEQQTAQQLFSEMKQWAQEMAKTSIEADFFAVSQPDLL
                     SLYGDLQQQHKEKCLMVAMLASAGLGEVAHYESARAELTAINPAWPKAALFTTVMPFI
                     FNRVH"
     gene            6858..8051
                     /locus_tag="IT892_001470"
     CDS             6858..8051
                     /locus_tag="IT892_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP3134701.1"
                     /translation="MRACINNQQIRHHNKCVIQELLYRQKRANKSTLARLAQISIPAV
                     SNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACL
                     SPKGEFEYLQIDAPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
                     MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIG
                     SSFVINEQIYRGCLYGSGQIGHTIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLK
                     SQPVNTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSLYNFLNILNINQIWL
                     YGRSCAFGEHWLNTIIRQTGFNPFDRDEGPSVKATKIGFGQLSRAQQVLGIGYLYVEA
                     QLRQI"
     gene            complement(8115..9368)
                     /locus_tag="IT892_001471"
     CDS             complement(8115..9368)
                     /locus_tag="IT892_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAP3134702.1"
                     /translation="MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVM
                     QAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQAN
                     FAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEK
                     QAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVP
                     HAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVAL
                     KEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEAD
                     AALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDS
                     INDEAVIERIKGKVLDICARYPVYA"
     gene            9697..10887
                     /gene="hmpA"
                     /locus_tag="IT892_001472"
     CDS             9697..10887
                     /gene="hmpA"
                     /locus_tag="IT892_001472"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HAP3134703.1"
                     /translation="MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFN
                     MSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGEHL
                     LATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAK
                     TPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYR
                     IAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLA
                     MLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGLSLPRFTAHTWYRQPSEADRAK
                     GQFDSEGLMDLSKLEGAFSDPTMQFYLCGPVGFMQFAAKQLVDLGVKQENIHYECFGP
                     HKVL"
     gene            complement(10932..11270)
                     /gene="glnB"
                     /locus_tag="IT892_001473"
     CDS             complement(10932..11270)
                     /gene="glnB"
                     /locus_tag="IT892_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II"
                     /protein_id="HAP3134704.1"
                     /translation="MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTE
                     LYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRI
                     RTGEEDDAAI"
     gene            complement(11331..12665)
                     /gene="glrR"
                     /locus_tag="IT892_001474"
     CDS             complement(11331..12665)
                     /gene="glrR"
                     /locus_tag="IT892_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator GlrR"
                     /protein_id="HAP3134705.1"
                     /translation="MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRV
                     LNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPVIILTAHGSIPDAVAATQQGVFS
                     FLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSV
                     LINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVS
                     NREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISAT
                     HRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQAAERHKPFVR
                     AFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFV
                     EARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE"
     gene            complement(12655..13368)
                     /gene="qseG"
                     /locus_tag="IT892_001475"
     CDS             complement(12655..13368)
                     /gene="qseG"
                     /locus_tag="IT892_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system QseEF-associated
                     lipoprotein QseG"
                     /protein_id="HAP3134706.1"
                     /translation="MRHIFQRLLPRRLWLAGLPCLALLGCVQSHNKPAIDTPAEEKIP
                     VYQLADYLSTECSDIWALQGKSTETNPLYWLRAMDCADRLMPAQSRQQARQYDDGSWQ
                     NTFKQGILLADAKITPYERRQLVARIDALSTEIPAQVRPLYQLWRDSQALQLQLAEER
                     QRYGKLQQSSDSELDTLRQQYHVLQQQLELTTRKLENLTDIERQLSTRKPAGNFSPDT
                     PHESEKPAPSTDEVTPDEP"
     gene            complement(13533..14960)
                     /gene="qseE"
                     /locus_tag="IT892_001476"
     CDS             complement(13533..14960)
                     /gene="qseE"
                     /locus_tag="IT892_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417051.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system sensor histidine kinase
                     QseE/GlrK"
                     /protein_id="HAP3134707.1"
                     /translation="MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQA
                     ALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHA
                     GVLPDDKLYQALRQDLNNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSR
                     GQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLG
                     NSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLA
                     DQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELENVELAPLVETV
                     VSAHSLPARAKMMHTDVDLQATACLAEPMLLMSVLDNLYSNAVHYGTESGNICLRSSL
                     HGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG
                     ELYLVDESGQDVCFRIELPSSKNTK"
     gene            complement(15517..19404)
                     /gene="purL"
                     /locus_tag="IT892_001477"
                     /gene_synonym="purI"
     CDS             complement(15517..19404)
                     /gene="purL"
                     /locus_tag="IT892_001477"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HAP3134708.1"
                     /translation="MMEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLN
                     APLNDDEHAQLERLLKYGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQ
                     VNRLERGVAYYIEAGTLTNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTS
                     VDLLGQGRQALIDANLRLGLALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCR
                     HKIFNADWVIDGEQQPKSLFKMIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHE
                     TGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVG
                     FSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTY
                     EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGG
                     GAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGL
                     SNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDEL
                     CKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGKTPKMTREVQTLKAKGD
                     ALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQMVGPWQVPVANCAV
                     TTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANW
                     MAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEGNEEREMTSPL
                     SLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPAD
                     VRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGIDADIATLGD
                     DRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHYVGQAVSGDRFVITANGQT
                     VFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINEDVA
                     APYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRTGLEDFHAL
                     VACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRE
                     LIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVR
                     DAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPE
                     RVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG"
     gene            19662..21218
                     /gene="mltF"
                     /locus_tag="IT892_001478"
     CDS             19662..21218
                     /gene="mltF"
                     /locus_tag="IT892_001478"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417053.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltF"
                     /protein_id="HAP3134709.1"
                     /translation="MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGE
                     LRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNSNA
                     DLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVV
                     VNDLQTLKETKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELA
                     VALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVD
                     TRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLT
                     KNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHML
                     DARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQIS
                     LVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLF
                     SRKGSEEKQN"
     gene            complement(21215..21751)
                     /gene="tadA"
                     /locus_tag="IT892_001479"
     CDS             complement(21215..21751)
                     /gene="tadA"
                     /locus_tag="IT892_001479"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAP3134710.1"
                     /translation="MRRAFITGVFFLSEVEFSHEYWMRHALTLAKRAWDEREVPVGAV
                     LVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCA
                     GAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVEITQGILADECAALLSDFF
                     RMRRQEIKAQKKAQSSTD"
     gene            complement(21776..22411)
                     /gene="yfhb"
                     /locus_tag="IT892_001480"
     CDS             complement(21776..22411)
                     /gene="yfhb"
                     /locus_tag="IT892_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311453.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase C"
                     /protein_id="HAP3134711.1"
                     /translation="MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPL
                     LPIIAIALLIKGRAARWPMSLLLWGCTFGHNEARLQALQADFVRWFRDNVTAFPLVQE
                     RLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRINLIASQIQRGYGGWVLTMRCL
                     GHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQHRWRVTPRGELQQLE"
     gene            22620..23468
                     /locus_tag="IT892_001481"
     CDS             22620..23468
                     /locus_tag="IT892_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP3134712.1"
                     /translation="MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEA
                     GVSQSSVVKFAQKLGYKGFPALKLALSEALASQPESPSVPIHNQIRGDDPLRLVGEKL
                     IKENTAAMYATLNVNSEEKLHECVTMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
                     AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPN
                     ALQQRASHCLYTIAEEQATNSASISACHAQGMLTDLLFIALIQQDLELAPERIRHSEA
                     LVKKLV"
     gene            23524..23784
                     /gene="yfhL"
                     /locus_tag="IT892_001482"
     CDS             23524..23784
                     /gene="yfhL"
                     /locus_tag="IT892_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster ferredoxin YfhL"
                     /protein_id="HAP3134713.1"
                     /translation="MALLITKKCINCDMCEPECPNEAISMGDHIYEINSDKCTECVGH
                     YETPTCQKVCPIPNTIVKDPQHVETEEQLWDKFVLMHHADKI"
     gene            complement(23979..24059)
                     /gene="shoB"
                     /locus_tag="IT892_001483"
     CDS             complement(23979..24059)
                     /gene="shoB"
                     /locus_tag="IT892_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin ShoB"
                     /protein_id="HAP3134714.1"
                     /translation="MTDCRYLIKRVIKIIIAVLQLILLFL"
     gene            complement(24479..24859)
                     /locus_tag="IT892_001484"
     CDS             complement(24479..24859)
                     /locus_tag="IT892_001484"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAP3134715.1"
                     /translation="MTILGLGTDIVEIARIEAVIARSGERLARRVLSDNEWAIWKTHH
                     QPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKL
                     GVVNMHVTLADERHYACATVIIES"
     gene            complement(24859..25590)
                     /gene="pdxJ"
                     /locus_tag="IT892_001485"
     CDS             complement(24859..25590)
                     /gene="pdxJ"
                     /locus_tag="IT892_001485"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HAP3134716.1"
                     /translation="MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITV
                     HLREDRRHITDRDVRILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQEVT
                     TEGGLDVAGQREKMRDACKRLADAGIQVSLFIDADVEQIKAAAEVGAPFIEIHTGCYA
                     DAKTDAEQAQELARIAKAATFAASLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAI
                     IGRAVMTGLKDAVAEMKRLMLEARG"
     gene            complement(25602..26330)
                     /gene="recO"
                     /locus_tag="IT892_001486"
     CDS             complement(25602..26330)
                     /gene="recO"
                     /locus_tag="IT892_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAP3134717.1"
                     /translation="MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRS
                     TLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEY
                     ETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDD
                     TMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLG
                     GKPLKSRELFRQFMPKRTVKTHYE"
     gene            complement(26342..27247)
                     /gene="era"
                     /locus_tag="IT892_001487"
     CDS             complement(26342..27247)
                     /gene="era"
                     /locus_tag="IT892_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAP3134718.1"
                     /translation="MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTR
                     HRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT
                     PDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGL
                     NVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEI
                     ERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLE
                     LWVKVKSGWADDERALRSLGYVDDL"
     gene            complement(27244..27924)
                     /gene="rnc"
                     /locus_tag="IT892_001488"
     CDS             complement(27244..27924)
                     /gene="rnc"
                     /locus_tag="IT892_001488"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003848606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP3134719.1"
                     /translation="MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLG
                     DSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELK
                     SGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRL
                     QEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQ
                     ALKKLELE"
     gene            complement(28197..29171)
                     /gene="lepB"
                     /locus_tag="IT892_001489"
     CDS             complement(28197..29171)
                     /gene="lepB"
                     /locus_tag="IT892_001489"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP3134720.1"
                     /translation="MANMFALILVIATLVTGILWCVDKFFFAPKRRERQAAAQAAAGD
                     SLDKATLKKVAPKPGWLETGASVFPVLAIVLIVRSFIYEPFQIPSGSMMPTLLIGDFI
                     LVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDP
                     VSKELTIQPGCSSGQACENALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETK
                     ENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNR
                     DNSADSRYWGFVPEANLVGRATAIWMSFDKQEGEWPTGVRLSRIGGIH"
     gene            complement(29187..30986)
                     /gene="lepA"
                     /locus_tag="IT892_001490"
     CDS             complement(29187..30986)
                     /gene="lepA"
                     /locus_tag="IT892_001490"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010434076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAP3134721.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSM
                     DLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVV
                     DAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
                     CSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLR
                     KGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTL
                     ARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSAL
                     GFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPA
                     VNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEV
                     VLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGDRVDALALITHRDNSQNRG
                     RELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQ
                     KQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK"
     gene            complement(31184..31663)
                     /gene="rseC"
                     /locus_tag="IT892_001491"
     CDS             complement(31184..31663)
                     /gene="rseC"
                     /locus_tag="IT892_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR-reducing system protein RseC"
                     /protein_id="HAP3134722.1"
                     /translation="MIKEWATVVSWENGQALVSCDVKASCSSCASRAGCGSRVLNKLG
                     PQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLMGLFLIASLFQLLFAS
                     DIAALCGAILGGVGGFLIARGCSRKFAARSEWQPIILSVALPPGLVRFETSSEDASQ"
     gene            complement(31660..32616)
                     /gene="rseB"
                     /locus_tag="IT892_001492"
     CDS             complement(31660..32616)
                     /gene="rseB"
                     /locus_tag="IT892_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseB"
                     /protein_id="HAP3134723.1"
                     /translation="MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYE
                     LSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPRREVVQRGNEISYFEPGLEPFTL
                     NGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
                     DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKA
                     KFSWTPTWLPQGFSEVSSSRRPLPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQM
                     LRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGAAQ"
     gene            complement(32616..33266)
                     /gene="rseA"
                     /locus_tag="IT892_001493"
     CDS             complement(32616..33266)
                     /gene="rseA"
                     /locus_tag="IT892_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-E factor RseA"
                     /protein_id="HAP3134724.1"
                     /translation="MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMR
                     GDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQPAPHQWQKMPFWQKVRPWAAQLT
                     QMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
                     GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ"
     gene            complement(33299..33874)
                     /gene="rpoE"
                     /locus_tag="IT892_001494"
     CDS             complement(33299..33874)
                     /gene="rpoE"
                     /locus_tag="IT892_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005070454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HAP3134725.1"
                     /translation="MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSG
                     DVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIE
                     AENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIA
                     AIMDCPVGTVRSRIFRAREAIDNKVQPLIRR"
     gene            complement(33871..34026)
                     /gene="rseD"
                     /locus_tag="IT892_001495"
     CDS             complement(33871..34026)
                     /gene="rseD"
                     /locus_tag="IT892_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rpoE leader peptide RseD"
                     /protein_id="HAP3134726.1"
                     /translation="MIRLQHDKQKQMRYGTLQKRDTLTLCLLKLQLMEWRFDSAWKFG
                     LGRLYLG"
     gene            34282..35904
                     /gene="nadB"
                     /locus_tag="IT892_001496"
     CDS             34282..35904
                     /gene="nadB"
                     /locus_tag="IT892_001496"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HAP3134727.1"
                     /translation="MNTLPDHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEG
                     STFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGV
                     LFDTHIQPNGAESYHLTREGGHSHRRILHAADATGREVETTLVSKALNHPNIRVLERS
                     NAVDLIISDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPD
                     ISSGDGIAMAWRAGCRVANLEFNQFHPSALYHPQARNFLLTEALRGEGAYLKRPDGTR
                     FMPDFDERGELAPRDIVARAIDHEMKRLGADCMYLDISHKPADFIRQHFPMIYEKLLG
                     LGIDLTKEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSL
                     LECLVYGWSAAEDITRRMPYAHGVSTLPPWDESRVENPDERVVIQHNWHELRLFMWDY
                     VGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELIVRCAMMRK
                     ESRGLHFTLDYPELLTHSGPSILSPGNHYINR"
     gene            complement(35889..36626)
                     /gene="trmN"
                     /locus_tag="IT892_001497"
     CDS             complement(35889..36626)
                     /gene="trmN"
                     /locus_tag="IT892_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417070.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(1)(Val)
                     (adenine(37)-N(6))-methyltransferase TrmN"
                     /protein_id="HAP3134728.1"
                     /translation="MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAG
                     VKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHT
                     ADIQQWITQQTVRFDLIISNPPYYQQGVECSTPQREQARYTTTLDHPSLLTCAAECIT
                     EEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFS
                     DRLVIRGPDQNYSEAYTALTQAFYLFM"
     gene            36758..38092
                     /gene="srmB"
                     /locus_tag="IT892_001498"
     CDS             36758..38092
                     /gene="srmB"
                     /locus_tag="IT892_001498"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase SrmB"
                     /protein_id="HAP3134729.1"
                     /translation="MTVTTFSELELDESLLEALQDKGFTRPTAIQAAAIPPALDGRDV
                     LGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVADHARELAKH
                     THLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
                     RMLDMGFAQDIEHIAGETRWRKQTLLFSATLEGDAIQDFAERLLEDPVEVSANPSTRE
                     RKKIHQWYYRADDLEHKTALLVHLLKQPEATRSIVFVRKRERVHELANWLREAGINNC
                     YLEGEMVQGKRNEAIKRLTEGRVNVLVATDVAARGIDIPDVSHVFNFDMPRSGDTYLH
                     RIGRTARAGRKGTAISLVEAHDHLLLGKVGRYIEEPIKARVIDELRPKTRAPSEKQTG
                     KPSKKVLAKRAEKKKAKEKEKPRVKKRHRDTKNIGKRRKPSGTGVPPQTTEE"
     gene            complement(38125..39006)
                     /locus_tag="IT892_001499"
     CDS             complement(38125..39006)
                     /locus_tag="IT892_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311470.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3134730.1"
                     /translation="MDLRRFITLKTVVEEGSFLRASQKLCCTQSTVTFHIQQLEQEFS
                     VQLFEKIGRRMCLTREGKKLLPHIYELTRVMDTLREAAKKESDPDGELRVVSGETLLS
                     YRMPQVLQRFRQRAPKVRLSLQSLNCYVIRDALLNDEADVGVFYRVGNDDALNRRELG
                     EQSLVLVASPQIADVDFTEPGRHNACSFIINEPQCVFRQIFESTLRQRRITVENTIEL
                     LSIESIKRCVAANIGVSYLPRFAVAKELASGELIELPFGEQSQTITAMCAHHAGKAVS
                     PAMHTFIQCVEECFLPG"
     gene            39109..39696
                     /gene="eamB"
                     /locus_tag="IT892_001500"
     CDS             39109..39696
                     /gene="eamB"
                     /locus_tag="IT892_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/O-acetylserine transporter"
                     /protein_id="HAP3134731.1"
                     /translation="MTPTLLSAFWTYTLITAMTPGPNNILALSSATTHGFRQSTRVLA
                     GMSLGFLIVMLLCVGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQA
                     KPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWVVGVSVLLAMIGTFGNVCW
                     ALAGHLFQRLFRQYGRPLNIVLALLLVYCAVRIFY"
     gene            complement(39758..40141)
                     /gene="grcA"
                     /locus_tag="IT892_001501"
     CDS             complement(39758..40141)
                     /gene="grcA"
                     /locus_tag="IT892_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autonomous glycyl radical cofactor GrcA"
                     /protein_id="HAP3134732.1"
                     /translation="MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGFAEDEVV
                     AVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSG
                     YAVRFNSLTPEQQRDVIARTFTESL"
     gene            40446..41135
                     /gene="ung"
                     /locus_tag="IT892_001502"
     CDS             40446..41135
                     /gene="ung"
                     /locus_tag="IT892_001502"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP3134733.1"
                     /translation="MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDV
                     FNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPG
                     FTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
                     FLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGEKPI
                     DWMPVLPAESE"
     gene            complement(41183..42220)
                     /locus_tag="IT892_001503"
     CDS             complement(41183..42220)
                     /locus_tag="IT892_001503"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HAP3134734.1"
                     /translation="MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRA
                     DGGRRPARDDKQSHPRDRKWEDSPWRTVSRAPGDETPEKADHGGISGKSFIDPEVLRR
                     QRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
                     ELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSC
                     AHFGVKGVVVQDEALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS
                     SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGV
                     LLGEWWRQNKA"
     gene            42427..42846
                     /gene="trxC"
                     /locus_tag="IT892_001504"
     CDS             42427..42846
                     /gene="trxC"
                     /locus_tag="IT892_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HAP3134735.1"
                     /translation="MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGET
                     LDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQERSGKVRFVKVNTEAERELSSRF
                     GIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL"
     gene            42915..43613
                     /locus_tag="IT892_001505"
     CDS             42915..43613
                     /locus_tag="IT892_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311476.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DTW domain-containing protein"
                     /protein_id="HAP3134736.1"
                     /translation="MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCS
                     TITPAQAKSRFCLLMFDTEPMKPSNTGRLIADILPDTVAFQWSRTEPSLDLLDLVQNP
                     DYQPMVVFPASYADEQREVIFTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDNLPVIS
                     VDLSRLSAYRLREAQAEGQYCTAEVAIALLDMAGDTGAAAGLGEHFTRFKTRYLAGKT
                     QHLGSITAEQLESV"
     gene            43645..46305
                     /gene="pat"
                     /locus_tag="IT892_001506"
     CDS             43645..46305
                     /gene="pat"
                     /locus_tag="IT892_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysine acetyltransferase"
                     /protein_id="HAP3134737.1"
                     /translation="MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPV
                     LPVTPAWKAVLGVLAWPDIASLPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSA
                     PASQHEDLRACALRHNMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVS
                     NTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFV
                     SAARSASRNKPILVIKSGRSPAAQRLLNTTAGMDPAWDAAIQRAGLLRVQDTHELFSA
                     VETLSHMRPLRGDRLMIISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPEHV
                     AISNPLDLRDDASSEHYVKTLDILLHSQDFDALMVIHSPSAAAPATESAQVLIEAVKH
                     HPRSKYVSLLTNWCGEHSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLR
                     ETPALPSNLTSNTAEAHLLLQQAIAEGATSLDTHEVQPILQAYGMNTLPTWIASDSTE
                     AVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTANEVQQAANAIFDRVKMAWPQA
                     RIHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEDQAVVALPPLNMN
                     LARYLVIQGIKSKKIRARSALRPLDVAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASG
                     SEFTALDVTLDIAPFEGDNESRLAVRPYPHQLEEWVELKNGERCLFRPILPEDEPQLQ
                     QFISRVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRIDQTEEILGVTR
                     AISDPDNIDAEFAVLVRSDLKGLGLGRRLMEKLITYTRDHGLQRLNGITMPNNRGMVA
                     LARKLGFNVDIQLEEGIVGLTLNLAQREES"
     gene            46419..47774
                     /gene="pssA"
                     /locus_tag="IT892_001507"
     CDS             46419..47774
                     /gene="pssA"
                     /locus_tag="IT892_001507"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HAP3134738.1"
                     /translation="MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKI
                     ASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPELDVRVLVDWHRAQRGRIGAAAS
                     NTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
                     HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLF
                     RQELRDAAYHFQGDADNDQLSVTPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNL
                     PAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSR
                     LQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHD
                     PQLELAPQREKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRI
                     L"
     gene            47820..48143
                     /locus_tag="IT892_001508"
     CDS             47820..48143
                     /locus_tag="IT892_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiM family lipoprotein"
                     /protein_id="HAP3134739.1"
                     /translation="MRILFVCSLLLLSGCSHMANDSWSGQDKAQHFIASAMLSAAGNE
                     YAQHQGMSRDRSATFGLMFSVGLGASKELWDSRPEGSGWSWKDFTWDVAGATTGYTVW
                     QLTRH"
     gene            complement(48140..49438)
                     /gene="kgtP"
                     /locus_tag="IT892_001509"
     CDS             complement(48140..49438)
                     /gene="kgtP"
                     /locus_tag="IT892_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoglutarate permease"
                     /protein_id="HAP3134740.1"
                     /translation="MAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFC
                     SLYFAHIFFPSGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCM
                     MCFGSLVIACLPGYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGF
                     YASFQYVTLIGGQLLALLVVVVLQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQL
                     DETSQQETRALKEAGSLKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGM
                     HANVASGIMTAALFVFMLIQPLIGALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVS
                     SPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYV
                     ALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL"
BASE COUNT        12003 a        13345 c        12502 g        11935 t
ORIGIN      
        1 caccggaaag cgccgtaccg ccaaccacga ccgcggcgat gacgtcaaac tccagaccgt
       61 ttgcggcacc tgcgttaccg gaaccgaggc gcgccgccaa caaaatgccg gtcaccgctg
      121 ctaataatcc cgaaagggta aaaataagaa tgcgtacccg acgaacgtta ataccgcaca
      181 actgtgctgc agtggcatta ccgccaacag caaaaaccga gcgcccgaag gcggttttgc
      241 ggctaatgaa cacaaacagc gcaaataaca ccatcatgat cagcgcggat accggcacac
      301 cgagaaattg tccccccagc cagtccagca cttcgttttc gtcaatcggc actggcaagg
      361 cgttcgtcat aaacagcccc attccgcgca gggcgctcca cagccccagc gtggccacga
      421 aacttggcac gttaaacacg ccgcgcagca ccccggcgag cgttcccatc agcgcgccta
      481 acagcaacac cagcagacaa gcaatcgcca acggaacttc aaattgcagc aaaaatgcca
      541 ggcacaccga gacaaaagcc accatcggcc caacgctgac atcaatttca ccggagataa
      601 taatcagcgt catcgcccag gcggcgatcc cgatggtggc ggcatcgcgc agcacgttca
      661 tctggttatt caatgagata aagcccggcg cgttcagaga gaagaccaga taaagaatgg
      721 cgatcaccac cagcaaaccg atctcattaa tatggcgact gacaaattgt ttgagcgaga
      781 cgctcttgcc ctgcggcaat ggtaatgacg aagcagacat cttcaggttc ctcggtaaaa
      841 ttcatcagtg cacagacaga atggcggaca tcagctcatc cacattgacc ggcgagtgaa
      901 actcctgcga gaacgtaccg tgctgtaata acaggatgcg gtcacacacc agcggcaact
      961 cctccacttc actggagata aacaccacac tttttccttc ggcagccagc tcgcggacaa
     1021 tacggtaaat ctgctgtttg gcttcgatat cgacgccacg cgttggctcg tcgagcaaca
     1081 aaatctggct ggcggcatag acccaacgac cgatcaccac tttttgctga ttgccgccag
     1141 aaagcgtgcc gatgggcgtt tcgctactgg cggccttgac cgtcatccgc tgcatcacct
     1201 cttcggtcag gcggcggatg gtggaccatt gcagcacacc gttggcgctg attttttgcc
     1261 gattggtcag cactgtattt tcgtcaacgc ccagccaggg aatgatcccc gcttctttgc
     1321 ggttttctgg cgtatagcca atgccgcgtt tcagcatgtc gccgtaatcg gggcgcgtga
     1381 ttttctcgcc gttgataaca atttcgccct gttcatacgt ctccagccca acaatcgcct
     1441 tcagcaattc actgcgccct gcccccagca ggccagcaat gccgagtact tcgccacgac
     1501 gtagcgtaaa gctgatatcc tccagcttgg gcttatggcg taacgcacgg acttccagca
     1561 cagcctgatc gacaatttcc tgaggggcaa ccggcgcaat atcaacgtga tcgcgcccga
     1621 gcattagcga cacaatatga tgcgtggagg tgttttcgag catcatatcg cccgccacct
     1681 gaccatcgcg cataacggtg gcacaggagg caatgcggcg gatttcttcc atccggtggc
     1741 tgacataaat caccgccacg cccagtgccg acatcttttt aaccgcactg atcaccagtt
     1801 caacttccgc actggcaagc gaactggtag gttcatcaag aatgaccacg cgcggctcgc
     1861 ccttcatcac ccgcgcaatt tccaccagtt gcttttgtgc cgggcttagc gttgaaacaa
     1921 gttgttcagg gctaacgtca acgcccagcg cctgtaagca acgttgggca tcctgcgcca
     1981 tttgcaggta atcaatcatg ccgttgcggc ggggccactg accgaggcag aggttttccg
     2041 ccaccgtcag tccctccacc agacttaact cctgataaac cgcacgaacc cccagttcag
     2101 cggcacggcg agtcaacgta gcttcgtcac cttccagtcg cgtctcgcca atccagatat
     2161 caccgctatc cggacgttca ctgccggtaa gcattcgaat gagggtcgat ttgcccgcgc
     2221 cgttttttcc taacagcgca cgaacttcgc ctttattgag cgtgaagtta acgttatcca
     2281 acgcaacgac gccgggataa cgcttatttc ctgccaccac ttttgctacc gggactgcct
     2341 ctgttgccgt gaacataggg acctctgcga atcagcgatt agggcagacc atcaacgtgc
     2401 gttgccagcc actgtttacc gtcttccgtt ttggtataga gatcgattgg cacctgaatc
     2461 actttttcac cgtcggcttg tttattgata accttcaaag tttgcgcgaa aacagcattg
     2521 cccattttct taccggaaat atccaccacc gctttcagca cctgattgtt ttccagctcc
     2581 tgagcaattt cagtggtcat atccgaaccg aaaacagcaa tttttccggc ctgattttga
     2641 ttacgtaccg cttttaccgc gccgagtgtc gcaccgcccg attcccccat aatggcgttg
     2701 agatccgacg tggagataat tagtttttca ccaacggaaa tcgctttatc taaaacagtc
     2761 ccttcctgat tagcgacaat ttgcgcgccg ggaacgcggg cttttaatac ttcttcaaac
     2821 cctttacgtc gttgcacaca aacttcaaag gcttcgcaat tgatgacggc aattttcggc
     2881 tggtcaattt tgttggcaat aaaataatcg gcggcagcgt tacccagttt tttaccaaat
     2941 tccagcgggt caccaaccag atatgccgag acatatttat cgacaccctt ttgattaata
     3001 caggtgttgt agcaaatcac cggaataccc gcttcactgg cgcgacgaac ggtacgacta
     3061 ctgccatttt cagacactgc cgataaaata atggcatcga cattacgcgc cacgagggta
     3121 tcaataaagg tactttcttt cgaaatatca ccctgggcgt tagtttcaat taactgtacc
     3181 tgtactgaag aatcttttgc cgcatcctga acgccctgac gcacgccagc gtaatatccc
     3241 tgggtatcaa ggtatattgc gccaatggtc atttctttat ccgcagccct ggcaaatagt
     3301 gcgctaccta atagcgtagc cattaataat agattacggg ttgttctcat ttttttaggc
     3361 atagtgcctc ctgtagggtt tttatttaca acggcttatt ttaattattt gagcgtgagc
     3421 ggcagcgcgt gccgctcaaa tattacagtt aataaggttt agtgaacgcg gttaaaaata
     3481 aaaggcatca cggtggtgaa taatgctgct ttcggccagg ccggattaat cgccgtcaat
     3541 tcagcgcgag cagattcata gtgcgcaacc tccccgagtc ccgcggacgc cagcatcgcc
     3601 accatcaggc atttttcttt atgctgctgt tgtaaatcgc catacagcga caacaggtca
     3661 ggttgtgaaa cagcaaagaa atccgcctca atactggttt tcgccatctc ttgcgcccac
     3721 tgtttcattt cactaaacag ttgctgtgcg gtttgctgtt cacccagcag tcgcagcgcc
     3781 attccttgcc agaagagata atcaaccggc tgatcgttgt aataactgtg aatgttaatg
     3841 gtgcgatcgc cagtcgccgc cagacgtaaa caacgcatcg cttcagtttg atcgccctgc
     3901 gcgttggcgc atatcgcctg ccagaaccag atgtcgttat cagtttgccc cggtaaacgg
     3961 ccttcgctta aattctccgg ataatgcagc gcggcatgaa gcagttcgct ggcctgctgc
     4021 ggctctctgg tatcaagatg ctgccaggcg cgtaataact ggttgaggat aaactgactg
     4081 gtgatcttcc cttccccgcc ttcccacggg tggaatttgc gcgtggcgag aatgtccgcc
     4141 gctttgtctg cctgacccgt gagatgccac aaattgagca gttctgcggt catgtcgtcg
     4201 cgtttcagcg caatttccag attattttcc agacgcgcca gtcgtttctc cggtgtggct
     4261 ccacttaact tatcaagcaa atcccgttcg aaaagcagac gtgcatcctg cggcgcaagc
     4321 tgataagcat tatcaagata acgcgcggcc agctcataat cgtgttgctt attccacgca
     4381 tggatcgcta agccgcgcca gccgtcggca aactccggcg acatctctac gcaacgttgc
     4441 cataaggcaa tggctttgtt gtagctacgt ttgttgtagt agaagcaggc cagtaaatga
     4501 cgggcaaacc agcactcttc aatactctcc agcgccgcca cttcttccag cgtattcggg
     4561 aaacggacaa actgtgggaa gacatcaatg gcttttgcga ccagttcgcc gcgttcagct
     4621 ttcggcagca agctggcttg caggtaaagc ggcagcgtgc gctggcagtc cagtgcgttt
     4681 agcatctctg ccgccagggt gggcattccc cagttaatca gttgcccggc ggtcatcagg
     4741 gcgttaacgt cgcgtccctg acacagaccg cgccactgcg cgagggctga ttcgctacga
     4801 ccatcgaacc agttcagcca ccacagagtg gcgttcagcg gataatcgcg cagcagtttc
     4861 tcgcgctgca aacgcgcgtt gtcctgacga ccacttaaca ccagcagcag attatgcagg
     4921 caaagcactt cctgattggt tgggcaggca cgaagacttt gttggcaaaa atccagacca
     4981 gcatcgaagt gaccattacg cgccgccagt cgtgccagac cataatagcc gcctgcttta
     5041 ctattgccgc tccagaccgc acgccagaaa tcctcttcgg cttgttgata ttgtccctga
     5101 cgttcgtaag cactggcgcg aatcaaactg gcctgtccgc actgcggatt tttgttcagc
     5161 gcatgtgcgc gtttcagcgc ctgagtggca tacgccaccg cttgcgggaa atcggcgcgg
     5221 ttatattcca gcatcgccag cgccaggtta cagcgataat ccagcggatc cagcgccacg
     5281 ccgcgcaggt agtaatcgaa cggtgaacgg ctggcgtgat gatattgctc cagatgctga
     5341 ccgataaacc aggcttcatc tgtactggca atgtcttgtg ctgccagtgg cgctttggcg
     5401 acgtccggca acggcaactc ttgcggctga tgttcctgat aactcagtat gatattgccg
     5461 tcggcatcgg agagttcaat ggtcagcctt tcaggattga taccgtgcaa cacgccctgg
     5521 atggcggtcg ctggtgtcag ggccacggca tcatcgagca acgcgttgca tttgccgatt
     5581 tcgcggatcg ccagacggta tcctttcaac ggagagatgg catacagccc ccactcaatc
     5641 ccccgctcgc tacgctggag tttaatcacc gcatcgcggg aggcgttttg caccatgccc
     5701 aaagaatggt aaggcaggaa atactgctca aaacgcttct cttcgtaagc atcaagccag
     5761 gtaaaatcgg gctggttatc ggcaaaaata ccagtcatca gttcgatata cgggccgtta
     5821 ttgtcggtca gactcttatc ccacgcctgg ccaaattcac tgtgtcccca gctccactgt
     5881 tttttacctg gcgcaatatg gtggttggca acgtgcagca aaccgccatc ttcatcgtga
     5941 caccacgcgc caacaaaatc gtactgtgat ttttcagcca tatatgaggt tggaacgggc
     6001 acatttttat agcgagaaat gtccactccg gcggagtagt ccactttgta gtaagtgccg
     6061 gtggcgatgg ggaaagcgga gacggcccgt ttgccgtgat caaacaccgc cgttacatcc
     6121 ggcgggaaga cgctctgatg cccttcaccc cctttcactg ccgggttggc ccaccacaag
     6181 aaatgacgcg gcgtggcgtt gccgttatag acgcggctgg cgatttccag cgccgcccgt
     6241 tcagggcgca gggtgaaacc tgtcatcacc tgtaaaccgt gcatcggctc cgtttcgccg
     6301 acccacacgg tttgtgcgcc gtcttcatgg gcttcgaggg tgaaatcgac gggcataaag
     6361 gtggtcgggc gatggtgttg cggccagtta aactcaatcc cgccggagat ccacggcccc
     6421 agcagcccca ccagcgccgg tttaatgact tcattatgat agacaaaatc gcgttgtttc
     6481 actttatccc acgcgcgatg cacccgaccg cccagctccg gcaggatcat cactttgatg
     6541 tagtcgtttt ccagccacac cgcctgccag gatttcaggg ttttctgctc gctcagcgta
     6601 tcggtcacgc cgtagggata aaccgcgccg gacgatccct gataaacgcg attttccagg
     6661 aacataggat gtatatcctg cggcccggtt tcataggtcg ggatctcaac gcgctcttgc
     6721 cacactttta ctggagtcat ggtgccctca atattaacaa gacatactga attaaaagat
     6781 ttgtggcagt gtattgaaca atctggcaat gttttcgcgg aataatcacg caattaacta
     6841 aacaaggttt agtgaagatg agagcctgca ttaataatca acagattcgc caccataaca
     6901 aatgcgtgat tcaggaactg ctgtaccggc aaaagcgcgc caataaatca acgctggccc
     6961 ggctggcgca aatttcgatt ccggcagtca gtaatatttt gcaggaactg gaaagcgaaa
     7021 aacgggtggt gaatatcgac gatgaaagcc agacgcgcgg gcatagtagc ggtacatggc
     7081 tgattgcgcc ggaaggtgac tggacgctgt gtctgaacgt aacgcccacc agtattgagt
     7141 gtcaggtcgc taacgcctgt ttaagtccga aaggtgaatt tgagtattta cagattgatg
     7201 caccgacgcc gcaggcgctg ctgtccgaaa tcgaaaaatg ctggcatcgc caccgtaaat
     7261 tgtggccgga ccgcaccatc aatctggcgc tggcaatcca cggtcaggtt gatcctgtga
     7321 ccggagtgtc gcaaaccatg ccgcaagcgc cctggacaac gccggttgag gtaaagtatc
     7381 tgctggaaga gaagctcggc attcgggtga tggtcgataa tgactgcgtg atgctggcgc
     7441 tggcggagaa atggcaaaat aattcgcagg aacgggattt ctgcgtgatc aacgttgatt
     7501 acggcattgg ctcgtcgttc gtgattaacg agcaaattta tcgcggctgt ttgtatggta
     7561 gcggacagat tggtcacacc atcgttaatc cggatggcgt cgtctgcgac tgcggacgtt
     7621 atggctgcct ggaaaccgtc gcctcgttaa gcgcattaaa aaaacaggcg cgggtatggc
     7681 taaaatcaca accggttaat actcagcttg atcctgaaaa actgacaaca gcgcagttaa
     7741 tcgctgcctg gcagagtgga gaaccgtgga tcaccagctg ggttgatcgc tctgccaatg
     7801 ccattggttt gagtctgtat aacttcctca acatcctcaa tattaatcag atttggttgt
     7861 acggtcgcag ttgtgccttt ggtgagcact ggcttaatac cattattcgc cagacgggat
     7921 ttaacccgtt cgaccgcgac gaaggaccga gcgtgaaagc gacgaaaatt ggctttgggc
     7981 aattaagccg cgcacaacag gtgctgggga ttggctattt gtatgttgag gcgcagttac
     8041 gacagatttg atggcgcgat aacgtagaaa ggcttcccga aggaagcctt ttttcaacag
     8101 attaaccgtt tcgcttacgc gtaaaccggg taacgtgcac agatgtcgag aactttacct
     8161 ttgatgcgct cgataacggc ttcatcattg atgctgtcca gcacgtcaca catccagcca
     8221 gccagttctt tcgcttcggc ttctttgaag ccacgacggg taatcgccgg agtacccacg
     8281 cgaataccgg aggtcacaaa cgggctcttc ggatcgttcg gtacgctgtt tttgttgacg
     8341 gtgatgttag cacggcccag agcggcgtcc gcttctttac cggtcaggtt tttatcaacc
     8401 agatcaacca ggaacaggtg gttatcagtg ccgccggaaa ccactttgta gccgcgttcc
     8461 aggaacactt ctaccatcgc tttagcgttt ttagcgacct gctgctggta agttttgaac
     8521 tcaggctcca tcgcttcttt cagagcaacc gctttaccgg cgattacgtg catcaacgga
     8581 ccgccctgac caccagggaa aacggcagag ttcagttttt tgtacagctc ttcgctacca
     8641 cctttcgcca ggatcaggcc gccgcgcgga cccgccaggg ttttgtgagt ggtggtagta
     8701 acaacgtgag catgaggaac cgggttcggg tagacgccag ctgcaaccag gcccgcaacg
     8761 tgcgccatat caacgaacag gtaagcaccg atgctgtcag cgatttcacg cattttcgcc
     8821 cagtccacca cgccggaata tgcagagaag ccaccgataa tcattttcgg tttgtgttct
     8881 ttggcttgtt tttccagatc ggcgtagtcg atatgaccgg tagcatcgat accgtaagga
     8941 acgatgttgt acagtttacc ggagaagtta accggagaac cgtgagtcag gtgaccgcca
     9001 tgcgccaggt tcatacccag aacggtatca cctggttcca gcagcgcggt gtacaccgca
     9061 aagttagcct gggagccgga gtgcggctgg acgttagcgt agtcagcacc gaacagttct
     9121 ttcgcacgat cgatcgccag ttgttcaacg atatcaacat actcgcaacc gccgtagtag
     9181 cgtttgcccg gataaccttc agcatatttg ttggtcagct gagaaccctg cgcctgcatt
     9241 acgcgcgggc tggtgtagtt ttcggaggcg atcagttcga tgtgctcttc ctgacgtact
     9301 ttttcctgct ccatagcctg ccacagttcg gcatcataat cggcaatgtt catttcacgc
     9361 tttaacatcc gcatctcctg actcagctaa caataaaatt tttggccttt ataggcggtc
     9421 ctgttggaca acggcgaaca gtataaccga atcattgtgt gataacaggt cttgacaaag
     9481 gaatttacgc aaacgattac cttcaggcta cgcaaggctt tggagaataa agagcttgca
     9541 accggaaacg gatttctttt caggtttgtg atgcaaattt ttcacttcat cacattcttt
     9601 ctgaaaaaca ccaaagaacc atttacattg cagggctatt ttttataaga tgcatttgag
     9661 atacatcaat taagatgcaa aaaaaaggaa gaccatatgc ttgacgctca aaccatcgct
     9721 acagtaaaag ccaccatccc tttactggtg gaaacgggac caaagttaac cgcccatttc
     9781 tacgaccgta tgtttactca taacccagaa ctcaaagaaa tttttaacat gagtaaccag
     9841 cgcaatggcg atcaacgtga agccctgttt aacgctattg ccgcctacgc cagtaatatt
     9901 gaaaacctgc ctgcgctgct gccagcggta gaaaaaatcg cgcagaagca caccagcttc
     9961 cagatcaaac cggaacagta caacattgtc ggtgaacacc tgttggcgac gctggacgaa
    10021 atgttcagcc cgggccagga agtgctggac gcgtggggta aagcctatgg cgtactggct
    10081 aatgtattta tcaatcgcga ggcggaaatc tataacgaaa acgccagcaa agccggtggc
    10141 tgggaaggta ctcgcgattt ccgcattgtg gctaaaacac cgcgcagcgc gcttatcacc
    10201 agcttcgaac tggagccggt cgacggtggc gcagtggcag aataccgtcc ggggcaatat
    10261 ctcggcgtct ggctgaagcc ggaaggtttc ccgcatcagg aaattcgtca gtactctttg
    10321 actcgcaaac cggatggcaa aggctatcgt attgcggtga aacgcgaaga gggtgggcag
    10381 gtatccaact ggctgcacaa tcacgccaat gttggcgatg tcgtgaaact ggtcgctcca
    10441 gcaggtgatt tttttatggc tgtcgcagat gacacaccag tgacgttaat ctctgccggt
    10501 gtcggtcaaa cgccaatgct ggcaatgctc gacacgctgg caaaagctgg ccacacagca
    10561 caagtgaact ggttccatgc ggcagaaaat ggcgatgttc acgcctttgc tgatgaagtt
    10621 aaggaactgg ggctgtcact gccgcgcttt accgcgcaca cctggtatcg tcagccgagc
    10681 gaagccgatc gcgctaaagg tcagtttgat agcgaaggtc tgatggattt gagcaaactg
    10741 gaaggtgcgt tcagcgatcc gacaatgcag ttctatctct gcggcccggt tggcttcatg
    10801 cagtttgccg cgaaacagtt agtggatctg ggcgtgaagc aggaaaacat tcattacgaa
    10861 tgctttggcc cgcataaggt gctgtgattt gatgttgccg gatggaaaca tccggcaacc
    10921 cttgacgcgg tttaaattgc cgcgtcgtct tcttcaccgg tacggatacg aatgacccgt
    10981 gccacgtcaa agacgaagat tttaccatca ccgattttgc cggtttgcgc cgtgcgaata
    11041 atggtatcga cacaggtatc gacaatgtcg tccggtacga caatctcaat tttcactttc
    11101 ggcagaaaat ccaccatata ctccgcgccg cggtacagct cggtatggcc tttctggcgg
    11161 ccaaaacctt tcacctcagt gaccgtcatg ccagtaatgc cgacttcagc cagtgcttcg
    11221 cgaacatcgt ccagcttgaa gggtttaata atcgcatcaa tctttttcat gctattcctt
    11281 gaaaaggtcg cctgtctttt gatctgctaa acgtaacaca taacgccaat tcattccttg
    11341 aaatcgtttg catccagctc gtgtcgggat agcagtttat aaaattctgt ccggttgcgc
    11401 cccgccattc tcgccgcgtg ggtgacgttg cctttggtaa tttgcagcag cttacgcaag
    11461 tagttgagtt caaactgatt acgcgcctca acaaaggttg gcagcgccgt gttttcgccc
    11521 tccagcgcct gctctactaa tgcatcgcta atcaccggag atgaggtcag cgccacgcac
    11581 tgttcaatca cgttgaccaa ctggcgtaca ttacccggcc agctagcggt catcaggcgt
    11641 ttcatcgcat cggtggagaa cgcgcggaca aacggtttat gtcgctctgc cgcctggcgc
    11701 aacaggtgat ttgccagtag cggaatgtct tctgtgcgct ctgccagagc cggaattttc
    11761 aggctgacaa cgttgaggcg gtaatagaga tcttcacgga attccccgcg cgccatcgct
    11821 tttggcaggt cgcggtgagt ggcggaaata atccgcacgt cgatatcaat atcgcggtta
    11881 ctgcccagcg ggcgcacttt acgctcctgc aacacgcgca gcagtttaac ctgcaacggt
    11941 gcgggcatat cgccaatctc atcgagaaat agcgtaccgc cttccgccgc ctggaataaa
    12001 ccttcgcgat tgctgacagc gccagtaaac gcgccacgcg catgaccaaa cagctccgac
    12061 tccagcaatt gctcgggcaa tgcaccacag ttaatagcaa taaatggttt gctattgcgc
    12121 gggctagcgt tgtggatagc ctgggcgaaa atctctttcc cggtgccgct ctggccatta
    12181 atcaaaacgc tgacgtctga ttgcgccacc agccgcgcct gttccagcaa acgcagcatc
    12241 agcgggctgc gggtgacaat cgcctcgcgc cagcgttcat cggtggctgg cgcggattgt
    12301 tccagcgcat catcaattgc ctgatatagc gcgtctttat cgacaggctt ggtgaggaaa
    12361 ctgaacactc cctgctgtgt tgcagcaacg gcatcgggaa tagaaccatg tgcggtaaga
    12421 ataattaccg gcattcccgg ctgcactttc tggatttcag caaacagctg cataccatcc
    12481 atttcatcca tccgcaggtc gctgataact aaatctactt tttcgcgatt cagtacccgt
    12541 aatccttcag caccactttc cgccgtgacc acgctgtagc cttcgctggt caggcgcagg
    12601 ccaagcagtt tcagcaatcc cggatcgtca tcgaccaata ataaatgcgc aggtttatgg
    12661 ctcatcagga gtgacctcat cggtggatgg cgcgggcttt tcactctcgt gtggcgtatc
    12721 cggcgagaaa tttccagccg gtttgcgggt cgagagctgg cgttcaatat cagtcaggtt
    12781 ttccagcttg cgggtggtga gttccagttg ctgctgtaga acgtgatatt gctggcgcaa
    12841 agtatccagc tcgctgtcgc tggattgctg gagcttgccg tagcgttggc gctcttccgc
    12901 cagttgcagt tgcagcgcct gactgtcgcg ccagagttga tacagagggc gaacctgtgc
    12961 cgggatctcg gtacttagcg catcaatgcg cgcgaccagc tggcggcgct catacggtgt
    13021 aattttggcg tcggcgagca aaatcccttg tttaaaggta ttttgccagc tgccgtcgtc
    13081 atattggcgg gcttgctgac gcgactgcgc aggcattaaa cgatcagcac aatccatcgc
    13141 ccgcagccag taaagcggat tggtttcggt tgatttacct tgcagcgccc agatgtcgct
    13201 acattcagta gaaagatagt cagccagttg ataaaccgga attttttctt ctgctggcgt
    13261 atcaatggct ggcttattgt gactctgcac gcaacccagc aatgccagac atggcagccc
    13321 tgccagccac agccgtcggg gcaataatcg ttgaaaaatg tgtcgcatat tcaccagact
    13381 tagcgccttt cccagtgggc gtaattgttg caggcagttt ggatacggac agcgcggaga
    13441 aaccggagcg tacatgtcgt acgtgaggat ttcgagcact gcccagggcc aaactggcaa
    13501 ataaaatagc ctgatgggat aggctgttag cattatttcg tgtttttcga cgacggcaat
    13561 tcaatgcgga agcaaacgtc ttgcccgctc tcgtcgacca gatacagttc cccttgcata
    13621 cggcgaatac aatccctggc aatgcttaat cccagaccgc tgcccttcac cgcccctttt
    13681 cgctggtggc ttccctgaaa aaagggttcg aagatcatgg cgcgttcctc ttgcggaatg
    13741 ggtgttcctg tattgatgac atcaatataa acccgcgcgc catgtaaact gctgcgaagg
    13801 caaatgttac cggattcagt cccgtagtgc acagcattgg agtaaagatt atccagtacg
    13861 ctcatcagca gcattggctc cgccaggcaa gctgttgctt ggagatcgac gtcggtatgc
    13921 atcattttag cccgtgcggg caggctatga gcagaaacta ctgtctccac cagcggtgct
    13981 aattcaacat tctccagttc caccgcactg tccgcctgtt tacggttgta atcaagcagt
    14041 tgttcgatca gtttttgcaa attgcggctg ctgctatcga ggatgctcac cacctctttt
    14101 tgctctggcg taagcggccc gacaacctgg tcagccagta attcagtgcc ctcgcgcata
    14161 ctcgccagcg gcgtttttaa ttcatgagat aaatgtctta agaattgatg acgttgggat
    14221 tccagccatg acaggcgctc acttaaccaa agaatacgtt gcccaaccga gcgtaactcg
    14281 ctcggtccac tgaacgaaac gctattgccc agagaacgcc cttcccccag ccggttgatc
    14341 atgcgctcga tatttttcac cggaccgata atcatcctcg tgaaaagtag caccatcacc
    14401 agactcacca gaaatagcac cagcgattgc caaccaaaat attgcccacg ttcggcgatt
    14461 tcacgctgaa gttgctgccc acgagagaac accactgtgc gcgtggcctg caccatttcg
    14521 gtattggcac tggcaaaggc ttcaagacgc gcggcggcgg cggcatcggg accactgttg
    14581 ttacactgaa gttgagccag attgttcaaa tcctgacgca atgcctggta aagtttatcg
    14641 tctggcagta cgcctgcgtg ggcatcgagc atttcgctgt aacgcttgcg ctggctttga
    14701 taaaccttcg caagcgtagg gtcgtccagc acgcaatact gacggtaact acgctccatc
    14761 tccagcgccg cgttggtcat cgcttcactg cgccgggcat caataagcgt agtgcggtta
    14821 accagcgccg cctgatcgct aagcgcattc aggctttgcc aggcttgcca tgccagcacc
    14881 aacaggggca gcagaatcag caaaaatgcc agcattacca gttgtcgtaa tgagcgggga
    14941 aaaacgggcc agcgtttcaa ggtgttactc tcgtcagacg cgaatagcct gatgctaacc
    15001 gaggggaagt tcagatacaa caaagccggg aattacccgg ctttgttatg gaataaggcg
    15061 gtgcctaact cgacgtttcg cccgatggtt gatatagcta cgctgatatc agaagttgga
    15121 cggcaggcac cttgttgtgc gtcattcgaa ttttatgtag cacgtcccga aggggctgac
    15181 ataagtcggt gaatgagcca ctgcttacta ttatgcagta actgtgccaa taaagaaaat
    15241 agtttggtaa cgtactgatt atacgctgct ttgagggatt tatggcttct tcgctatttg
    15301 aatgtaaatc agccactgtg tcgctaaaaa gagacaactt aagataaact tattagatac
    15361 tattaaaatc aatcagttaa gtgtcgccag aaagcgacac ggtaaaccac ccattgtcgt
    15421 gatttacaga cacaaaaaag ctcccgaagt tgggagctta taatagcggt tggtgcttaa
    15481 tgccggatgc ggctgcaaaa ccaatgggtt gacggcttat cccaattgct tacgtgcatt
    15541 gcggaaaata cgcatccacg gcccatcctc gccccagttt tccggatgcc aggagttgct
    15601 gacagtacgg aaaacacgtt ccgggtgcgg catcataatg gtgactcgac cactttcagt
    15661 cgtaaccgcc gtaataccgt tcggtgaacc gttcgggtta gccgggtagg tttcagtgac
    15721 tttaccgaag ttatcgacat agcgcagtgc caccagccct ttgctttcca gtgccgccag
    15781 atgcgccgca tcacgcactt ccacgcgccc ttcaccatga gatacagcaa tcggcatttg
    15841 cgagcccacc atcccctgca acagcagaga cgggctttgg gttacttcaa ccaggctgaa
    15901 acgcgcttca aagcgatcgg aggtattgcg cacaaaacgt ggccacaact cactacctgg
    15961 gatcagttcg cgcagattag acatcatctg gcaaccgtta cataccccca gcgccagcgt
    16021 ttgcggacgg tggaagaagg ttgcaaactc atcgcgtaca cggtcattga acaggataga
    16081 cttcgcccaa ccttcaccgg cacccagcac atcaccgtag gagaaaccac cgcacgcgac
    16141 cagggcgtgg aaatcctcca ggcccgtgcg tccagccagc aggtcgctca tatgcacgtc
    16201 gatagcatcg aagcctgcac ggtggaaagc tgccgccatt tcaacatgcg agttcacgcc
    16261 ctgctcacgc agcacagcaa ctttcggacg tgcgccagtg gcaatatacg gtgctgccac
    16321 atcttcgttg atatcgaacg acagttttac attcaggccc ggatcggcgt cgtttgattt
    16381 cgcctggtgc tcctggtcgg cacactccgg gttgtcacgc aggcgctgca tctgccaagt
    16441 agtttctgcc caccagacac gcaacgtggt gcggctttcg ctgaatacag tctgcccgtt
    16501 ggcggtaatc acaaaacggt caccggaaac cgcctgccca acataatgga cgcaatccgc
    16561 aagcccatgc tgtgccagta ccgcttcaac tgcttcacgg tcagcggcac gaacctgaat
    16621 caccgcaccc agttcttcgt taaacaacgc cgccaggcga tcgtcaccca gagtggcgat
    16681 atccgcgtca atgccgcaat gaccagcaaa ggccatttcc gccagcgtta ccagcaggcc
    16741 gccatccgag cggtcgtggt acgcgagcag cttacgctgt gcaaccagcg cctgaatcgc
    16801 gtcatagaag cctttcagtt gggcaacgtc gcgtacatct gccggtttgt cgccaagctg
    16861 acgataaacc tgcgccagcg ccgttgcgcc cagcgcgtta ttgcctttgc ccagatcaat
    16921 cagcagtaat gcgttatctt cggtagaaag ctgcggcgtg atggtgtgac gcacatcttc
    16981 cacacgggca aatgcagaaa tcaccagcga cagcggcgac gtcatttcgc gctcttcgtt
    17041 accttcctgc cagcgggttt tcatcgacat agagtcttta cccaccggga tcgtcaggcc
    17101 cagcgccgga caaagttctt cgcccacagc tttaacggct tcatacaggc ccgcatcttc
    17161 accagggtgg cctgccgccg ccatccagtt ggcggaaagt ttaatgcgtt tgatatcgcc
    17221 aatctgtgtt gcggcaatat tggttaacgc ttcaccgacc gccagacggg cagaggcggc
    17281 gaaatctagc agcgcaaccg gcgcacgctc gccaatcgcc atcgcttcac catagtagct
    17341 gtcaaggctg gcggtagtga ccgcgcagtt agcgaccggc acctgccacg gacccaccat
    17401 ctgatcgcgc gccaccatgc cagttacgct gcggtcaccg atggtcacca ggaaagtttt
    17461 ctctgccaca gtcggcagat gcagtacgcg tttcaccgcg tcagcgatgg tgatcccttc
    17521 acgaaccagc gcatcaccct tcgctttcag cgtttgtact tcgcgggtca tcttcggcgt
    17581 tttaccaagc aggacgtcca gcggcagatc gatcggctga ttatcaaaat gacgatcgtg
    17641 caaagaaaga tgcagttctt cggtcgcttc accaatcacc gcgtatggcg cgcgctcacg
    17701 cttacacagt tcgtcaaaca gcggtaactg atcggcagca accgccagca cgtagcgttc
    17761 ctgggattcg ttacaccaga tttccagcgg gctcatgccc ggttcgtcgc tcaggatatc
    17821 gcgcagttcg aatttaccgc cgcgcccgcc gtcgctcacc agttccggca tggcgttaga
    17881 aagaccgcca gcgccgacgt cgtggataaa caggattggg ttggcatcac caagctgcca
    17941 gcaacggtcg atcacttcct ggcagcgacg ctccatctcc gggttgtcgc gctgtacgga
    18001 agcaaagtcg aggtcggcat cagactgacc agacgccatg gaagacgccg cgccgccgcc
    18061 aagaccgatg ttcattgccg ggccgccgag aacgaccagc ttcgcaccaa cgttgatctc
    18121 gcctttttgt acgtgatcgg cgcgaatgtt gccgatcccg cccgccagca tgatcggttt
    18181 gtgataaccg cgcagctctt cgccattgtg gctattcact ttttcttcat aagtacggaa
    18241 gtagccgttc agtgccggac gaccaaattc gttgttaaat gccgcgccac caagcgggcc
    18301 ttcggtcatg atgtccagcg cggtgacaat gcgctcaggc ttaccgaaat cttcttccca
    18361 cggttgttca aagcccggaa tacgcaagtt ggaaacggag aaaccaacca aaccagcttt
    18421 cggcttcgcg ccgcgcccgg tggcaccttc atcgcggatt tcaccgccgg aaccggtcgc
    18481 cgcgcccggc cacggagaaa tcgccgtcgg gtggttgtga gtttcgactt tcatcagaat
    18541 atgcgccggt tcctgatgga aatcgtagcg gcccgtttcg tggtcagcaa agtagcggcc
    18601 cacttcagaa ccttccatta cggcggcgtt atctttataa gcagagagaa cgtgatccgg
    18661 cgtggtttcg aaggtgtttt tgatcatctt aaacagcgat ttcggctgct gttcaccatc
    18721 gataacccag tcggcgttaa aaattttgtg gcggcagtgc tcggagttcg cctgggcaaa
    18781 catatacagt tcgatgtcgt tcgggttacg accaagcttt gtgaaagcat cctgcaaata
    18841 gtcaatttca tcttccgcca gtgccaggcc aagacgcagg ttagcgtcga ttagcgcctg
    18901 acggccctgc cccagcaaat caacgctggt gaccggagtc ggttgatggt gtgcaaacag
    18961 ctgctctgca tcatctaaag caaaaaagac cgtttccatc atgcggtcgt gcagttcagc
    19021 ggtaacctgc tgccattgtt cattggtcag cgtaccggct tctatatagt aagccacgcc
    19081 gcgctcaaga cggtttacct gttgcagccc gcagttatgg gcaatatcgg tcgctttcga
    19141 agaccaggga gagatggtgc caggacgcgg ggtcaccagc aggagtttgc cttgcggggc
    19201 gtggctggcg agtgccgggc catatttcag caggcgttca agttgtgcgt gctcatcatc
    19261 gtttaacggc gcattgaggt cagcaaaatg gacatactcg gcgtaaatag tgtgaaccgg
    19321 gagcctggca gcctgaaaac gtgccagcag tttgttgatt cggaatgccg acaatgcagg
    19381 cgaaccacgc agaatttcca tcataagtct ctcgtcttct aagctttcgg tgtacccaag
    19441 ggggggaaac gggcgtcatt ataaagaatc tgatgcgctg acgaaaccgt ttgcgtggaa
    19501 ataaaatcac catcgcgaat tagcaacgcg tgccgccact ggctgtaata agttgccaac
    19561 tggcgcaggt ttacgcaaaa tgccgctcat ttatgagtaa acctttcact attattactt
    19621 tttttcaagc tgggacgcgc acgacacaga gaattaacta attgaaaaaa ttaaagatta
    19681 attatctgtt catcggcatt ctggcactgc tgctcgcggt cgctctctgg ccatccattc
    19741 cctggtttgg taaagccgac aaccgtatcg ccgccattca agcgcgggga gagttgcgtg
    19801 tgagcaccat tcatactccc ctgacgtata acgaaatcaa cgggaaacct tttggcctgg
    19861 attacgaact ggcgaaacag tttgccgatt acctcggcgt aaaactgaaa gtgaccgtgc
    19921 ggcagaatat cagccagctg tttgacgacc tcgataatag taacgccgac ctgctggcgg
    19981 caggactggt ctataacagc gaaagggtta aaaattatca gccaggcccg acctactact
    20041 ccgtttcaca acaactggtt tataaagtgg gtcagtatcg cccacgtaca ctgggcaacc
    20101 tgacggcgga gcaactcacc gttgcaccgg gtcatgtggt ggttaacgat ctccagaccc
    20161 tgaaagaaac aaaattcccg gaattaagct ggaaggttga cgacaaaaaa ggctctgcgg
    20221 aattaatgga agatgtcatc gaaggaaaac tcgattacac cattgctgat tctgttgcca
    20281 ttagcctgtt tcagcgcgtt catccggaac tcgccgtagc gctcgacatt accgatgaac
    20341 aaccggtgac ctggtttagc ccattagatg gcgataatac cctttccgcc gctctgctcg
    20401 atttcttcaa cgaaatgaat gaagacggta ctctggcacg cattgaagag aaatacctgg
    20461 ggcatggcga tgattttgat tacgtcgata cgcgcacatt tttacgcgcc gtcgatgcgg
    20521 tactgccgca gttaaagccc ctgtttgaga aatacgccga agaaattgac tggcgtttgc
    20581 tggccgctat tgcttatcag gaatcgcact gggatgcgca ggccacttca ccgacgggtg
    20641 tgcgcggcat gatgatgcta accaaaaata ccgcgcaaag cctcggcatt acggatcgta
    20701 ccgatgccga acagagcatc agcggcggcg tgcgttattt gcaggatatg atgagtaaag
    20761 tgccggaaag tgtgccggag aacgaacgga tttggtttgc cctcgccgca tacaatatgg
    20821 gctatgcgca tatgctggat gcccgcgctc tgacggcaaa aaccaaaggc aatcctgaca
    20881 gttgggctga cgtaaaacag cgtctgcctt tacttagcca gaaaccctat tacagcaagc
    20941 tgacttacgg ctacgctcgt gggcatgaag cctacgctta tgtcgaaaat attcgtaagt
    21001 atcagattag cctggtgggt tatctgcaag agaaagagaa gcaggctaca gaagcggcga
    21061 tgcaactggc gcaggattat ccggcggtat cgcctacgga gttgggcaaa gagaaatttc
    21121 cttttctctc gtttctttcc cagtcgtcat caaactattt gacccattct ccctctctgc
    21181 tgttttccag gaaagggagt gaagagaaac aaaattaatc cgtcgaggat tgcgcttttt
    21241 tctgcgcttt aatttcctgg cggcgcatgc gaaagaagtc actgagcaac gccgcgcact
    21301 catccgccag tattccttgg gtaatttcca ctcggtgatt catacccgga tgatgcagca
    21361 catccattaa agatcccgca gcgccagttt tcgcgtcacg cgcaccaaag accacgcgac
    21421 caatgcgact gtggatcatc gctccggcac acattacaca gggttcaagc gtgacataca
    21481 acgtggcgtc gatcagacga taattttgca tcaccagacc gccctgccgc agagccatga
    21541 tttctgcatg tgcggtggga tcatgtcgac caatcggacg gttccagcct tcgccaataa
    21601 cacgattgtt atgcactaat accgcgccga ccggcacttc ccgctcatcc caggcacgct
    21661 ttgccagcgt cagcgcgtga cgcatccagt attcgtggct aaattcgact tcagacaaaa
    21721 agaaaactcc ggttataaaa gcgcggcgca ttatacacgg acgctatgct ttactctatt
    21781 ccagttgctg gagttcaccg cgcggggtta ctcgccaacg atgctgacag aaataaagca
    21841 gcgggttgtc ctgattactg tcgctatagc cactgtacaa ccgcagtggc gtgccgattt
    21901 tacgctccag ttgcgcgacc ttttcatgtc ccagacaacg catcgtcaat acccaaccac
    21961 catagccacg ctgaatctga ctggcgataa gattaatccg cggcagccag ggcgtatcga
    22021 aataaaccgc ttcaaccagc ggctgcggag agccggtaat caaccagata tcagcatcgg
    22081 aacttaacag gtaggtggtt aatcgctcct gaaccagcgg aaaggcggta acattgtcac
    22141 gaaaccagcg tacgaaatcg gcctgcaacg cctgcaaacg cgcttcattg tgaccaaaag
    22201 tgcatcccca cagaagcaga ctcatcggcc agcgtgccgc acggcctttt atcaataacg
    22261 caatggctat gatcggcaac aacggcagga caagcaacgc attcagcggt tggcgacgca
    22321 gtaaataacg caaaaaactg ccgaacatat cctgctgatg caatgttcca tctaagtcaa
    22381 aaaacaccac acgacgctcg tgagttgcca aaccatactc ctctggactg aaacatcctg
    22441 attaattttc gctactacat agcctaacag atagatcatc acttttccgg caacaatcga
    22501 ccgcatcatg gctaactgga atttttaatt catggaaatt agcggcaatg gaatataaaa
    22561 ttcactcgcg tttgtctcat attgcctgtt gtcgccacta tttcatcgcg aggaaagata
    22621 tgaacggctt acttcgtatc cgtcagcgtt accaggggct tgcccagagt gataaaaaac
    22681 tggcggatta tcttctgcta caacctgata cggcgcgcca tttaagctct cagcaactgg
    22741 ccaacgaagc cggagtcagt cagtccagcg tcgtgaagtt cgcgcaaaaa ctcggctata
    22801 aaggttttcc ggcgcttaag ttggcgttga gtgaagcgct ggcaagccag ccggaatcgc
    22861 cctccgtgcc cattcataac caaatccgcg gtgatgatcc gttacggctg gtcggcgaaa
    22921 aactgattaa agaaaatact gccgctatgt acgcaacgct aaacgttaat agtgaagaga
    22981 aactgcatga atgcgtaaca atgttgcgct ctgcgcggcg gataattctg accggcattg
    23041 gcgcttcggg tctggtggcg caaaactttg cctggaagct gatgaagatt ggcttcaatg
    23101 ctgccgcagt gcgcgatatg catgcgctac tcgctaccgt acaggcgtcg tcccctgacg
    23161 atctgttatt agccatttct tacaccggtg tacgacgcga gttaaacctg gcggcagatg
    23221 agatgctgcg agtgggcgga aaagtgctgg cgattaccgg ctttactccg aatgccctgc
    23281 aacagcgtgc ttctcattgc ctgtatacca ttgccgaaga acaagcgaca aacagtgctt
    23341 caatctctgc ttgtcacgcg cagggaatgt taacggattt gctgttcatt gcgctgattc
    23401 agcaggatct ggaactggct ccagaacgta ttcgtcacag tgaagcgctg gtgaaaaaac
    23461 tggtctgagt aaagaatgcg cgtataatgc ccgcccggtt tgtgttgttt tgagagtttc
    23521 cttatggcgc tgttaatcac taaaaaatgc atcaattgtg atatgtgtga acccgaatgc
    23581 ccgaatgagg cgatttcaat gggcgatcat atctatgaga ttaacagcga taagtgtacc
    23641 gaatgcgtag ggcactacga gacaccaacc tgccagaagg tgtgcccgat ccccaatact
    23701 attgtgaagg atccgcaaca tgtcgagacg gaagaacagt tgtgggataa atttgtgctg
    23761 atgcatcacg cggataaaat ttaatattct gctcctggag tagactattg ttgactttat
    23821 agtgtgagcc ttcaggttct tatatttatt ttcgtgatgt gatcataaat atcaattatt
    23881 tcatgaatga taacactatc tgtataagca cttatttata attattaaag gcgcgcctgg
    23941 ctggttaacc tgacgcgcct taagtacgtt tccttatgtt ataagaacag aaggatcagc
    24001 tgtaaaacag caatgatgat tttgatgacc cgtttaataa ggtatcggca atcagtcatt
    24061 cgtttttcct taaacaagga atgcagccgt tcagattagc ccttacatct ccccaaaact
    24121 gaacgtgcga gttattgagg gtgcatgctg cactccacac cagagctttg acgacaccac
    24181 tcgtttcaat gggggaattc tgtggcatgg tataaagcac agcaaaatcg ccaataacga
    24241 agccaatttt aatgtacttc cgaattggcg gtcacgttaa tctttccatc aatattgttt
    24301 tcttcgtaaa ggctcgagtt tttatgctaa agattgcaag ttgcttgtaa aagataaccg
    24361 ccctgatcca taatcgctct tgttgagggt gcgtgctgca caaaattaaa gttaaaaagt
    24421 aaaacccccg ttccttacca gttcgggggt tttactttat aaagagaacg gtattttttt
    24481 aactttcaat aattaccgtg gcacaagcat agtggcgttc atctgccagc gttacatgca
    24541 tatttacaac gccgagcttt tccgccagtt ttaatgcctc accccatagc cgtagccgtg
    24601 gtttgccgag ctcatcatta aatacttcaa attgattaaa cgccagacca ttgcggatcc
    24661 cggtgccaaa cgcttttgcc gccgcttctt tcacagcaaa acgcttcgcc agaaaacgca
    24721 ccggctggtg gtgcgttttc cagattgccc attcgttatc gcttaatacg cggcgtgcca
    24781 ggcgctcacc ggatcgggcg atcaccgctt ctatgcgagc gatctccaca atatccgtac
    24841 ctaaacctaa tattgtcatt agccacgcgc ttccagcatc agacgcttca tttctgccac
    24901 cgcatctttc agtccggtca tcactgcacg accaataatg gcatgaccga tattcagttc
    24961 atgcatctca gggatggcgg caatagcttt cacgttgtga taggtcagac cgtgaccagc
    25021 gttaactttc agaccgagac tagcggcaaa ggtcgcggct ttggcgatac gcgccagctc
    25081 ttgcgcctgt tcggcgtcag ttttggcatc agcatagcaa cctgtgtgga tctcgataaa
    25141 cggtgcgcca acctctgccg cagctttgat ctgctctaca tcggcgtcga taaacagaga
    25201 aacctggatc ccggcatctg ccagacgttt gcaggcatcg cgcatttttt cacgctgccc
    25261 tgcgacgtcc aggccgcctt cggttgttac ttcctgacgc ttttcaggta ccaggcagca
    25321 aaaatgcggc tttgtttcaa cggcgatcgc cagcatctct tcggtcaccg ccatctccag
    25381 attcatgcgg gtatccagcg tctgacgcag gatgcgcaca tcacggtcag taatgtggcg
    25441 gcgatcttca cgtaaatgca cggtaatgcc gtctgctccc gcctgctcag caataaacgc
    25501 cgcctgcacc ggatccgggt aagcagtacc gcgtgcgtta cgcagcgttg caatatggtc
    25561 aatgttgacg cctaacagta attcagccat gacaatcctc atcattcata atgtgttttc
    25621 accgttcgct taggcataaa ctgccggaac agttccctgc tctttaatgg tttaccgcca
    25681 agatacggct taagcgccat gcgggtaaag cgtttcgcgg cgcgcagtgt gtctgcgtca
    25741 ggaaattccc gcgcgtttaa cgcttttaac tgccttccgg tgaacgtttt attgtcgata
    25801 acgacgcttg cgataaaccc tttttcttcg cgataacgat acgtcatggt gtcatctacc
    25861 ggctcgccgc tacccgcaca atgggtaaaa ttgacgccat agcccagatg cccgagcagt
    25921 gccagttcaa agcggcgcag cgcgggttct ggcgtaccag tgaccccggc aagagactga
    25981 atgcagtgca agtaatcgaa aaagagttca gagaagcgcg tctcgtattc cagtacgcgg
    26041 gagagaagtt cgttgatgta cagaccgctg taaagcgtga taccgcttaa tggcagcgcc
    26101 agcgagacgg cttcagcact gcgcagcgtt ttgacttcgc cacgcccgcc gaaacgtagc
    26161 aagagagggg tgaaaggctg taatgcacct ttcagagtag agcgtttaga gcgtgcgcct
    26221 ttggcaacca gacgcacgcg acccgattcc tccgtgaaga cgtccagcat caggctggtt
    26281 tcgctccacg ggcgactatg caggacaaat gcgcgctgcc agccttccat cggagttact
    26341 cttaaagatc gtcaacgtaa ccgagactgc gcagtgcgcg ttcgtcgtcg gcccaaccgg
    26401 atttcacttt tacccacagc tcaaggtgaa caggcgcttc gaacatttcc tgcatgtctt
    26461 tacgcgcttc aatcccgatg gttttgatct tggccccttt gttgccaata accatcttct
    26521 tctgcccttc acgctcaacg agaatcaaac cgttgatgtc ataaccgcct cgttcgttag
    26581 agacgaaacg ttcgatctcc acggtcacgg agtacggcag ttcagcgccg aggaaacgca
    26641 tcagtttttc gcggatgatt tcagacgcca taaaacgctg tgagcgatcg gtgatgtaat
    26701 cttccgggaa gtgatgggtc gcttcaggca gatgcttacg cacgattgct gcgatagtgt
    26761 cgacattcag cccggtttca gcagagatcg gcacgatatc gaggaagttc atctggcttg
    26821 ccaggaactg taagtgtggc agcagatcgg ctttttcctg cacgttgtcc actttgttca
    26881 ccgcgaggat taccggcgct ttgccatcac gcagcttgtt gagcaccatt tcgtcgtccg
    26941 gcgtccagcg ggtgccttca acgacaaaaa tcaccagctc aacgtcgcca atggagctgc
    27001 tcgccgcttt gttcatcagg cggttaatgg cgcgtttttc ttccatatgc aggcccgggg
    27061 tatcgacgta gatcgcctga tacgcgcctt cagtatggat ccccacaatg cggtgacgag
    27121 ttgtctgcgc cttgcgggag gtgatagaga tcttctgccc caacagtttg ttcaataatg
    27181 tggatttgcc aacgttcgga cgtccgacga tagcaataaa tccgcagtaa cttttatcga
    27241 tgctcattcc agctccagtt ttttcaacgc ctgttcggcg gcagcctgct cagccttacg
    27301 acggcttgaa cctgtgccaa ccaccggttc actcaggccg ctgacctggc agtggatagt
    27361 aaattcctga tcgtgtgctt cgccacgtac ctggacgacc agataagtcg gcagcggcag
    27421 atggcgaccc tgcaaatatt cttgcaagcg cgttttcgga tctttttgtt tatcgcctgg
    27481 gctaatttcg tccagacggg tttgatacca gttaaggatt aatttctcga cggtttgaat
    27541 atcactgtcg aggaatacgc caccaattaa tgcttcgacg gtgtcggcga gaattgactc
    27601 acgacgaaat ccaccgcttt taagttcacc tggccctaaa cgtaagcact cgcctaactc
    27661 aaattcgcgc gccagttcag ccagcgtatt gccacggacc agcgtggcgc gcatccggct
    27721 catatcgcct tcatccacac gagggaaacg gtgataaagc gcattggcga taacgtagct
    27781 cagaatagag tcgcctaaaa attctaaacg ctcgttatgt ttgctgctgg cactacgatg
    27841 agttaatgcc tgctgcaaca gttcctgatg attaaaagtg tagcccagct tccgttgaag
    27901 ccgattaatt acgatggggt tcatgcgata ccaataaata aatgcgtcaa caattcagca
    27961 cacgaaacag acctgatata catggttctg ctaactgctt cgctgcagtt tcagtttacc
    28021 ggtatatggg gaccaacgct gtttcgtgtg ccgtggcaac ctggaggtgc caaccttaaa
    28081 cttcggggga atattctata cacaacgacg ggggatgtcg ttagccacgg gagatttatc
    28141 tcataaataa ttcacgttgt cgccataacg gcgacaacgt gaacgaagat gggctattaa
    28201 tggatgccgc caatgcgact taagcgcaca cctgtcggcc attcgccttc ttgcttatcg
    28261 aagctcatcc agatagccgt tgcccgaccg accagattcg cttccggcac aaagccccag
    28321 taacggctgt ccgcgctgtt gtcgcggttg tcacccatca tgaagtattg tcccggcgga
    28381 acaatccagg ttgccagttg ttgccctggc tgctggtaat acatccccac ctggtcctgc
    28441 gcaatcggca ctgtcagaat gcggtgcgtc acatcaccca gtgtctcttt acgctcggaa
    28501 agacgaattc cattttcttt ggtttcgttt ttcggcactt caaagaatcc gctggtcgct
    28561 tccccaccat tacggcgtga gaaggtctga acgaaatcgc tcggttccac gttggagtag
    28621 gtgaccggca gcgcgttttc acatgcctga ccggaactgc atcccggttg aatcgtcagc
    28681 tctttcgaga ccggatcata agtgacttta tcgcccggta aacccaccgc gcgcttgatg
    28741 taatcaagct ttggatcttc cggatattta aagaccacga tatcgccgcg tttcggatga
    28801 ccggtttcga tcagcgtttt ctggtagata ggatctttaa tgccataagc aaacttctct
    28861 accagaataa aatcaccgat taacagagtc ggcatcatcg aacctgacgg gatctggaac
    28921 ggttcataaa taaacgaacg cacaatcaat acgatagcca gcaccggaaa aacagaagca
    28981 ccggtttcca gccagccagg cttcggcgca actttcttca gcgttgcttt atccagtgag
    29041 tcaccggcag ccgcctgcgc cgctgcctga cgttcccgcc gtttaggtgc gaaaaagaat
    29101 ttatccacgc accataaaat gcccgtcacc agtgtggcaa tcaccagaat cagggcaaac
    29161 atattcgcca tgccaactcc taagggttat ttgttgtctt tgccgacgtg cagaatggcg
    29221 aggaacgctt cctgcggcag ctcgacgtta ccgatctgct tcatgcgttt cttaccttct
    29281 ttctgcttct gcagcagctt tttcttacgg ctgatatcgc cgccataaca tttagccagt
    29341 acgtttttac gcagctgttt cacggtggag cgcgcaatga tgtgcgtacc aatcgctgcc
    29401 tgaatggcga tatcaaactg ctggcgtggg atcagatctt tcatcttctc caccagctcg
    29461 cgaccgcggt tttgcgaatt atcacggtgg gtgatcaacg ccagcgcatc aacacgatca
    29521 ccgttgatta atacgtctac acgtaccatg tcggacgcct ggaagcgttt gaagttgtaa
    29581 tccagagacg cataaccacg cgaggtagat ttcaggcgat cgaagaaatc gagcaccact
    29641 tccgccatcg ggatctcgta cgtcagcgcc acctgattac cgtggtaaac catattggtc
    29701 tgcacgccgc gtttttctac gcacagtgta ataacgttgc cgagatatgc ctgcggcagc
    29761 agcatgtgac actctgcaat cggctcgcgc agttcgtaga tgttatttac cgctggcagc
    29821 ttggatgggc tgtcgacgta gataacttct cttgacgtgg tttcaacttc atacactacg
    29881 gtcggcgcag tggtgatcag atccagatcg tattcacgtt ccagacgttc ctggatgatc
    29941 tccatgtgca gcaggccgag gaagccgcag cggaaaccaa agcccagcgc gctggagctt
    30001 tccggctcat agaacagtga agcatcgttc aggctgagtt tgcccagcgc gtcacggaag
    30061 gcttcatagt cgtcggaact taccgggaac agaccggcgt atacctgcgg tttgactttc
    30121 ttaaagccag gcagcgcctt ttctgccgga ttacgcgcca gcgttaaggt atcgcctact
    30181 ggagcgccgt ggatatcttt aatcgcacat accagccaac ctacttcgcc acatttcagt
    30241 tcagtgcggt caacctgttt tggcgtgaag atacccagac ggtcggcgtt ataggtctgc
    30301 ccggtactca tgactttcac tttgtcgccc ttacgcaggg tgccgttttt aatacggata
    30361 agtgaaacaa cgcccaggta gttgtcgaac caggagtcga taatgagtgc ctgcaacggg
    30421 ccttccggat cgccttccgg cggcggaatg tcgcgcacca gacgttcgag aacgtcctgc
    30481 acgccaacgc cggttttcgc tgaacagcgc accgcgtcgg tggcgtcgat gccgacaata
    30541 tcttcaattt cttccgccac gcgttcagga tcggctgccg gcaggtcaat cttgttcagt
    30601 accggcacca cttcgagatc catttccatg gcggtgtagc agtttgccag ggtttgcgct
    30661 tctacgccct gcccggcgtc gaccaccagc aatgcacctt cacaggcagc cagcgaacga
    30721 gaaacttcat aagagaagtc aacgtggccc ggggtgtcga taaagttaag ctgataggtt
    30781 tcgccgtcag acgctttgta gtccagcgtc acgctttgcg ctttgatggt aatgccacgc
    30841 tcacgctcaa gatccatgga atcgagaacc tgcgcctcca tttcacggtc agacaggcca
    30901 ccgcagatct ggataatacg gtcagacagc gtcgatttac cgtggtcaat gtgagctatg
    30961 atcgaaaagt tacgtatatt cttcataaag tatgattatt gtgccttaat gcccggttaa
    31021 ccaggctttt agaagtcgct gttctgagct taacgtctgt attaatagaa acgccgcatt
    31081 ctacactaca acattgaggc gaggaaatgt tcataccgta tggattgtgg tatctggaaa
    31141 cgtcctcgca tttgttatgc aaaatgcaac aaagccagtg aaatcactgg ctcgcgtctt
    31201 ccgaagatgt ttcaaatcgc acaaggccag gcggcaatgc cacgcttaag atgatcggtt
    31261 gccattcaga ccgggcagca aactttcgag agcagccacg tgcaatcagg aatccaccaa
    31321 cgccaccgag aatcgcaccg cataatgctg caatatctga agcaaagagt agctgaaata
    31381 gtgaagcgat gaggaatagt cccatcaacg gcgacatata aaccagtaat gcggagctaa
    31441 gcaggctgcc ttcggcgatt cctaattcta ctttttgccc cggcactaac ggctcatcac
    31501 agggtacgac aatggtatgc gtggtttgcg ggccaagttt attcaacacg cggctaccgc
    31561 aaccggcacg tgaagcgcag ctgctgcatg aggctttaac atcacaactg accagcgcct
    31621 gcccgttttc ccaggagacg acggtagccc actctttgat cattgcgctg ccccgaactt
    31681 aatattctcg gcaatgcgtt tcgccgtttg cggcggcagt tcaccgacaa tggtgatttc
    31741 ggcgttatca cgtacgcttg tactgacggt tctgcgtccg gtgcgcaaca tctgatcggt
    31801 gctcgatggc gtagcgcggt taacgtttac cgaaaagctg aataatccgt cggaatagag
    31861 acgtgattcg ataggcatgt tgtccatcgt cggtagcgga cgtcggctac tggaaacttc
    31921 gctaaaaccc tgtggcaacc aggttggcgt ccagctgaat ttagcttttt cacctacagg
    31981 aacagaaagc aacggcggca aatttgcctt cgccagcgtc tgcatactgc tgctgatatc
    32041 ctgattgaca ttaaaagcaa tcacgcgaaa ttgttccagc gtttcaccat cgcgatcaag
    32101 gagatcaacc ctcatcggta atttcgattc ggtgtccatc cacacgatgt agctgtagcg
    32161 tgtaccatct cgggcaacca cgcgaataac ttcgcaaaga cgatcagcaa tacgcgtgcg
    32221 cccgacggag ataaagtcgt agtaaggaga aaggcgtttg aaatcggtat agatgagcga
    32281 tggcagagaa tcaacaatgt aatcgccatt aagcgtgaac ggttcaagtc ccggttcaaa
    32341 atagctgatt tcattgccgc gctgtaccac ttcccggcgc gggccatcca tttgcaacaa
    32401 ttgtgcaaga ggacggttat cgaggcgtgc atgtcgataa cgcagagact caacaccctg
    32461 tttattgatg ctgatgaatg acagctcgta attcagtgac tgactggcca ggttcatctg
    32521 ctgtaataac gccccggacg cgggggtggc cgaggcgtta gcagagaata acaggctacc
    32581 tgtcactaat gacatggcaa accaaagttg cttcattact gcgattgcgt tcctaaagtt
    32641 tgaattcctg gcacctgtac agcggcttgc tgggtttgcg cctgctcaaa ctgaagctgt
    32701 tcagagtgga gtcggcgttg cagttcgtaa tcctgcaaca ttgcattaat gcgacgacgc
    32761 tgctcctgta cctgctgctg ttgaccatta tttgcggtcg cttcagaagg tactcccagg
    32821 ctaaccgggc tggctttacc catcatcggc agtgtattaa ataccggcgt ttcgggctgc
    32881 tgggacgttt cagattgtcc attatagtgc tggacgccaa cgataactgc aagcgatacg
    32941 catgcggcta cgcccatttg ggtaagctgt gccgcccacg gacgtacttt ctgccagaat
    33001 ggcattttct gccattgatg cggcgcaggc tgggcttccg ggatcaatgt cgccggttga
    33061 cgtactggct cttcttcaat ggcggccatc acgcgtgaag agatatcgaa atggagcacc
    33121 tcgggagtat caccccgcat tgagtcacgg attaagtgat agctttccca ggttttctgc
    33181 atttctgggt tatgagccag ttcgttaagc agctcactat ccagcgtttc gccatccatt
    33241 aaagcggaaa gttgttcttt ctgcatgcct aataccctta tccagtatcc cgctatcgtc
    33301 aacgcctgat aagcggttga actttgttat caatagcttc cctcgctcgg aagatacgtg
    33361 aacgcaccgt acctaccgga caatccatga tagcggctat ctcttcatag ctcaggccat
    33421 ccagctcccg caaggttatt gccatgcgta aatcttccgg gagggactca atagttcgga
    33481 aaactatctg tctcagttct tctgacaaca ttaagttctc agggttcgaa atttctttca
    33541 acgcgccgcc actttcgaag ttttcagctt caatggcatc cacatcactg gaaggtggac
    33601 gacgcccctg agcaaccagg taatttttcg ctgtatttac agcaatccga tacagccatg
    33661 tataaaaagc gctatctccc cggaacgaat ccagcgcacg ataggcttta ataaaagctt
    33721 cttgtaccac atcgggaaca tcacccgacg gcacatagcg ggaaaccaga ctcgccactt
    33781 tatgctgata gcgcactacc agtaagttaa aggctttctg atctcccttc tggacccgtt
    33841 caaccaggac ctggtccgtt aactgctcgc tcatccgagg taaagtctcc ccaaaccaaa
    33901 tttccacgcg ctatcgaaac gccactccat tagctgcaat ttgagcaagc aaagggttag
    33961 agtgtctcgt ttttgtaaag ttccgtaacg catctgtttt tgtttgtcat gctgtagacg
    34021 gatcattatc tatcattata agtctacaga atctgaacat cgcattatct gtgtagaaat
    34081 gcccatttaa ctgcctgaag agtaacccaa cggccttttt atttcaccac ctaatcctcc
    34141 accagccagt aacttctctt tttctcgccg ccctgcgtca gcgtgtttag ccactgtaac
    34201 aaatattaaa atagcaggtg tttaatcgca caacatgatg ctatgctgac caaaccgtgt
    34261 ttagtaaatt aaacaaagaa aatgaatact ctccctgatc attcatgtga cgtgttgatt
    34321 atcggtagcg gcgcagccgg actttcactg gcgctgcgcc tggctgatca gcatcaggtc
    34381 atcgttctaa gtaaaggccc ggtaacggaa ggttcaacat tttatgccca gggcggtatt
    34441 gccgccgtgt ttgatgaaac tgacagcatt gactcgcatg tggaagacac attgattgcc
    34501 ggggctggta tttgcgatcg tcatgcagtt gaatttgtcg ccagcaatgc acgatcctgt
    34561 gtgcaatggc taatcgacca gggggtgttg tttgataccc acattcagcc aaatggcgca
    34621 gaaagctacc atctgacccg tgaaggtgga catagtcacc gtcgtattct tcatgccgcc
    34681 gacgccaccg gtagagaagt agaaaccacg ctggtgagca aggcgctgaa ccatccgaat
    34741 attcgcgtgc tggagcgcag caacgcggtt gatctgatta tttctgacaa aattggcctg
    34801 ccgggcacgc gacgggttgt tggcgcgtgg gtatggaacc gaaataaaga aacggtggaa
    34861 acctgccacg caaaagcagt ggtactggca accggcggtg cgtcgaaggt ttatcagtac
    34921 accaccaatc cagatatttc ttctggcgat ggcattgcta tggcgtggcg cgcaggctgc
    34981 cgggttgcca atctcgaatt taatcagttc caccctagcg cactgtatca cccacaggca
    35041 cgcaatttcc tgttaacaga agcactgcgc ggcgaaggcg cttatctcaa gcgcccggat
    35101 ggcacgcgtt ttatgcccga tttcgatgag cgcggcgaac tggccccgcg cgatattgtc
    35161 gcccgcgcta ttgatcatga aatgaaacgc ctcggtgcgg attgtatgta tctcgacatc
    35221 agccataagc ctgccgattt tattcgccag catttcccga tgatctatga aaaactgctc
    35281 gggctgggca ttgatctcac aaaagaaccg gtgccgattg tgcctgctgc acactatacc
    35341 tgcggtggtg taatggttga tgatcatggg cgtacggacg tcgagggctt gtatgccatt
    35401 ggcgaggtga gttataccgg cttacacggc gctaaccgca tggcctcgaa ttcattgctg
    35461 gagtgtctgg tctatggctg gtcggcggca gaagatatca ccagacgtat gccttatgcc
    35521 cacggcgtca gtacgttacc gccgtgggat gaaagccgcg ttgagaaccc tgacgaacgg
    35581 gtagtaattc agcataactg gcacgagcta cggctgttta tgtgggatta cgttggcatt
    35641 gtgcgcacaa cgaagcgcct ggaacgcgcc ctgcggcgga taaccatgct ccaacaagaa
    35701 atagacgaat attacgccca tttccgcgtc tcaaataatt tgctggagct gcgtaatctg
    35761 gtacaggttg ccgagttgat tgttcgctgt gcgatgatgc gcaaggagag tcgggggttg
    35821 catttcacgc tggattatcc ggaactactc acgcattccg gtccatcgat cctttccccc
    35881 ggcaatcatt acataaacag ataaaaagcc tgggtcagcg ccgtatacgc ttcggaatag
    35941 ttctggtctg gcccacgaat gactaagcga tcgctaaagc attctcctgc ctgcggggag
    36001 aatgccagca gcacccgatg cggcagtcgc gcttcgtttt ccgccacatc cgtccgcaaa
    36061 cgtaaatgcc agcccatact taatgccagt tcagtaaaac cattaccaat ctgctctggc
    36121 agcaccacgc agaaaaatcc ctcttcggta atgcactccg ccgcacaggt cagcaacgat
    36181 gggtgatcaa gcgtagtggt atagcgagcc tgttcccgtt gaggtgtcga gcactctact
    36241 ccctgctgat agtaaggtgg gttactgatg attaaatcga agcgtactgt ctgctgtgtg
    36301 atccactgct gaatatccgc cgtatggacg ttaatccgct ctgcccacgg ggactggttg
    36361 atattttcct gcgcctgcgc ggcagcttca ctttccagtt caactgcatc aatcattacg
    36421 ctgtcatcgg ttcgctgcgc cagcattaat gccagcaacc cgctacccgc gccgatatca
    36481 aggcaacgtt ttaccccagc caccggtgcc catgcgccca gcaaaatgcc atccgttcca
    36541 actttcatcg cacaacgatc gtgagcaaca aaaaactgtt taaaagtaaa tccattacga
    36601 cgaagcacgg atgtagactg tgacatgaaa ataaaacctt gcaggaaaaa cggcgatagc
    36661 accgggtgag aacaataccc gagaagcgat atccatacaa acagatgaag attgcagccg
    36721 taacgtctat aatcagcgcc ccacacagag gtagaacatg actgtaacga ctttttccga
    36781 acttgaactc gacgaaagcc tgctggaagc cctccaggat aaaggtttca ctcgcccgac
    36841 cgccattcag gctgccgcca ttccgcctgc gctcgatggc cgtgatgtac tcggttctgc
    36901 gccgacaggc accggtaaaa cggcggcgta tctgctgcca gcgttgcagc acctgctcga
    36961 tttcccacgt aagaaatccg gtccgccgcg tattttgatc ctcaccccaa ctcgcgagct
    37021 ggcgatgcag gtagccgatc atgcccgcga actggcgaaa catacgcatc tggatattgc
    37081 caccatcacc ggcggcgtag cctatatgaa ccacgcggaa gtgttcagcg aaaatcagga
    37141 catcgtggtc gccacgaccg gacgtctgct gcaatacata aaagaagaga acttcgattg
    37201 ccgcgcggtt gaaacgctga tcctcgacga agcagaccgt atgctggata tgggcttcgc
    37261 tcaggatatc gaacatattg ctggcgaaac gcgctggcgt aaacagaccc tgctcttttc
    37321 ggcaactctg gaaggcgatg cgattcagga ctttgccgag cgtctgctgg aagatccggt
    37381 ggaggtttct gccaatccgt ccacccgtga gcgcaaaaaa attcatcagt ggtattaccg
    37441 cgccgatgac ctggaacata aaaccgcatt gctggtgcat ctgttaaaac agccggaagc
    37501 gacccgctca attgtgtttg tgcgtaagcg tgagcgtgtg catgagctgg caaactggct
    37561 gcgcgaagcg ggcatcaaca actgctatct cgaaggtgag atggtacaag gcaagcgtaa
    37621 cgaagcgatc aagcgtttga ccgaaggccg cgtaaacgta ctggttgcca ccgatgttgc
    37681 tgcacgcggt atcgacattc ctgatgtcag ccacgtcttt aacttcgata tgccgcgcag
    37741 tggtgatact tatttgcacc gtatcggacg taccgcgcgc gccggtcgta aaggcaccgc
    37801 aatttcgctg gtggaagccc atgaccatct gctgctgggc aaagttggcc gttatattga
    37861 agagccaatt aaagctcgcg taattgatga gttacgcccg aaaacgcgtg caccaagcga
    37921 gaagcagacc ggcaagccat cgaagaaagt actggctaaa cgtgccgaga agaaaaaagc
    37981 taaagagaaa gagaagccgc gggtgaaaaa acgccatcgc gacaccaaaa atattggtaa
    38041 gcgccgtaaa ccaagcggaa cgggcgtgcc tccgcaaacg acagaagagt aatttcaatg
    38101 ccgggtttaa gcccggcatt atttttatcc cggcaaaaaa cactcttcaa cacactgaat
    38161 aaaagtgtgc atcgccgggc taaccgcttt tccagcatgg tgtgcgcaca ttgctgtaat
    38221 cgtctgcgac tgttcgccaa aaggcaattc gattaactcg ccgctcgcca attcttttgc
    38281 taccgcaaag cgcggcaggt agctgacccc gatattcgcc gcgacacaac gtttgatact
    38341 ttcaatgctt aacagctcaa tggtgttttc caccgtgatc cgccgctggc gcagcgtgct
    38401 ctcaaatatc tgccggaata cacattgcgg ttcgttgata ataaagctac aggcgttatg
    38461 tcttcccggc tcagtaaaat cgacatctgc aatttgcggt gaagctacca gcaccagcga
    38521 ttgctcaccc aattctcgtc ggtttagagc atcatcattc cctacgcggt aaaagacgcc
    38581 gacatcagcc tcatcattca gtagcgcatc acggatcacg taacagttca gagactgcaa
    38641 cgataaacgc acttttggtg cgcgttgccg aaaacgctgc aacacctgcg gcattcggta
    38701 agaaagcaac gtttcgcctg aaacaacgcg tagttccccg tccggatccg actctttttt
    38761 ggcagcctca cgaagggtat ccatcactct ggtgagttca taaatgtgcg gcagcagctt
    38821 ttttccttcg cgggtaaggc acattcgtcg accaattttc tcaaataact ggactgagaa
    38881 ctcctgctca agctgctgaa tatgaaaagt caccgtcgat tgtgtgcagc acaatttttg
    38941 cgaagctcgc aaaaaggaac cctcttccac cacggtttta agcgtaataa aacggcgcag
    39001 atccataacc ccaaacctat cgaaaatatc gaatttagaa tgtaaaaaca ttcatttttt
    39061 taaatgttcc gtgtcgggta ctgtctacca aaacagagga gataacaagt gacaccgacc
    39121 cttttaagtg ctttttggac ttacaccctg attaccgcca tgacgccagg accgaacaat
    39181 attctcgccc ttagctcagc tacaacgcac ggatttcgtc agagtactcg cgtgctggca
    39241 gggatgagtc tgggattttt aatcgtcatg ttgctatgcg tgggaatttc gttttcactg
    39301 gctgttatcg acccggcagc agtgcatctg ttgagctggg caggagcggc atatattgtc
    39361 tggctggcat ggaaaatcgc taccagtcca acaaaggaag acggacttca ggcaaaacca
    39421 atcagctttt gggccagctt tgctttgcag tttgtgaacg tcaaaatcat tttgtatggc
    39481 gttacggcac tgtcgacgtt tgtcctgccg caaacgcagg cgctaagctg ggtagttggc
    39541 gtcagcgttt tgctggcgat gattgggacg tttggcaatg tgtgctgggc gctggcgggg
    39601 catctgtttc agcgattgtt tcgccagtat ggtcgcccgt taaatatcgt gctggcgctg
    39661 ttgctggtct attgtgcggt acgcattttc tattgaaaga caaaaagaaa agcggaagag
    39721 gtcaccctct tccgcttaat aacttgctac ttaagcctta caggctttca gtaaaggtac
    39781 gagcgataac gtcgcgctgc tgttccggag tcagagagtt aaagcgaact gcataaccgg
    39841 atacacggat ggtcagctgc ggatattttt ccggatgctt aactgcatct tccagagttt
    39901 cacgacgcag aacgttaacg ttcaggtgtt gaccaccttc aacgcgaact tctggtttca
    39961 cttctactgg aacttcacgg tattcaatat cacccagttt gcttactgca accacttcgt
    40021 cttctgcaaa acctgctttc gcaacgatgc aacgcgcttc gcctttttcg ctgtccagca
    40081 gccagaaaga gttcagcaga tcgtcgttag cggctttagt aatctggata cctgtaatca
    40141 tgtgatgcct ccccggcaaa attatttgat ttgttcagcc tgtcgcggcc aattggtaaa
    40201 accattgttg cttgagtgta tatatactcc tcaaacaccc ttgaatcttt gatttaaatc
    40261 aataaaaacc acacatcaag tatggttgca aatggatttt attgttttac atcaacttat
    40321 gcaggtgtga aattttacca atttacattt ttttgcactc gtttaagtct aaaaaatgag
    40381 catgattttg ttctgtagaa agaagcagtt aagctaggcg gattgaagat tcgcgggaga
    40441 gcgagatggc aaacgaatta acctggcatg acgtgctggc tgaagagaag caacaaccct
    40501 attttcttaa taccctacag accgtcgcca gcgagcggca gtccggcgtc actatctatc
    40561 cgccacaaaa ggatgtcttt aacgcgttcc gctttacaga gttgggtgac gttaaagtgg
    40621 tgattctcgg ccaggatcct tatcacggac cgggacaggc gcatggtctg gcattttccg
    40681 ttcgccccgg cattgcgaca ccgccgtcac tgctgaatat gtataaagag ctggaaaata
    40741 ctattcccgg tttcacccgc cctaatcatg gttatcttga aagctgggcg cgtcagggcg
    40801 ttctgctact caatactgtg ttgacggttc gcgcaggtca ggcgcattcc cacgccagcc
    40861 tcggctggga gaccttcacc gataaagtca tcagcctgat taaccagcat cgcgaaggcg
    40921 tggtgttttt gttgtggggc tcacatgcgc aaaagaaagg ggcgattatt gataagcaac
    40981 gccatcacgt actgaaagcg ccgcatccat caccgctttc tgcgcatcgt gggttctttg
    41041 gctgcaacca ttttgtgctg gcaaatcagt ggctggaaca acgtggcgag aaaccgattg
    41101 actggatgcc agtattaccg gcagagagtg agtaaatttg caggaaaacg ccggatggca
    41161 gcgttgccac ccggctgatt tatcaggctt tattctgacg ccaccattca ccaagcaaaa
    41221 cgccagttgc gacagagata tttagcccgg caacgttgcc agtaccgtca atcttcacgc
    41281 gcagatcgtt tggatcgcgt gcggcatccg gtaacccttc atattcctga cccagcacca
    41341 gtaccatttt cgctggcaga ctggttttga acagcggttt cccctgctcg ctggaagtgg
    41401 tcactacggt gtaacctgcc tgacggaaat catccagcac gttaacaatg ttgtcgccag
    41461 taatcggctg aacgtgctct gcgccgcctt ctgcggtacg gatagccgcc cccgactcca
    41521 gcagtgcctc atcctgcacc acaacgcctt tcacgccgaa gtgcgcacag ctgcgcatca
    41581 tgccacccag gttatgcggg ttagattcgt tttccagtgc cagaacgcaa tcctgcgcgc
    41641 ctgcctggct tacccactgc tgcacggttg taccgttacg ctttttgatc aggaagcaaa
    41701 cgccgccgtg atgttccgtg cctgacgctt ttgtcagttc cgcttcatct accacatggt
    41761 acgctttgcg gtttgctgcc atccagcgca aggcttcttt aaaacgcggc gttacactct
    41821 ggataaacca ggcgcgaaca atcgcttccg gacggctctg gaacagtgcc tgacaggcat
    41881 tttcgccgta gacgcgggtt tcttccgcac gctgacgacg caaaacttcc ggatcaataa
    41941 aacttttacc actgatgcca ccgtgatcgg ccttttccgg cgtctcatca cccggcgcgc
    42001 gggaaaccgt gcgccacggc gaatcttccc acttgcggtc acgggggtga ctctgtttgt
    42061 catcgcgggc ggggcgacgg ccaccgtcag cacgagattt tcctggacgc ccgccccctt
    42121 tcccggtacg cgggttgtgg gtacgtttat cagaatcatc atcactgcgg acatacatca
    42181 ctttgacctt gccgctttta cctttcattt catcgttcat gcttttctcc accagcgctg
    42241 cgcgaagcgc gcagattacc cgaagtccgc gcggttcgcc atgatttcgt accaaagcct
    42301 gcgactatca tacctattga ataaaacaga ttgttgtctg gaacaatgtc cccgataata
    42361 tgtaacatat tagaaacata ccggcgtcgt tgccgataag tctccttact catcccgagg
    42421 ttagttatga ataccgtttg tacccattgt caggccatca atcgcattcc cgacgatcgg
    42481 atcgaagatg cggcaaaatg cggacgctgc ggtcacgact tgtttgacgg agaggtgatt
    42541 aatgcgaccg gtgaaacgct cgacaaattg ctgaaagatg atctacctgt ggtgatcgac
    42601 ttctgggcac cgtggtgcgg cccctgccgt aatttcgcac caatttttga agatgtcgcg
    42661 caagagcgta gcggtaaagt gcgctttgtg aaagtgaata ccgaagctga acgtgaattg
    42721 agcagtcgct ttggaattcg tagtataccg acgatcatga ttttcaaaaa cggtcaggtt
    42781 gtcgacatgc ttaatggcgc agtaccgaaa gcgccgtttg atagctggct gaacgaatct
    42841 ctttaatctt accggggcgc atcttgtgcc ccgttttctc ctctgcgaca atggcgtttt
    42901 ttcgacgctc tcttatgacc gaaaacgctg ttctccagtt acgcgccgag cgtattgcgc
    42961 gcgcaacacg tccttttctt gcccgcggta atcgcgttcg tcgctgccaa cgctgtcttt
    43021 tgccagagaa attatgtctc tgttcgacaa ttaccccagc acaagcaaaa agtcgcttct
    43081 gtttgctgat gttcgacacc gagccaatga agcccagtaa taccgggcgt ctgattgctg
    43141 atattttgcc tgataccgtt gcgtttcaat ggtcgcgtac cgaaccctcg ctagatttgc
    43201 tggatctggt acaaaacccg gactatcagc caatggtggt ctttcccgcc tcgtatgctg
    43261 atgagcaacg ggaagtgatc ttcacaccac ctgccggtaa gcctccgcta tttatcatgc
    43321 tcgatggtac ctggcctgaa gctcgcaaga tgtttcgtaa aagtccgtat ctggataatc
    43381 ttcccgtcat ttccgtcgat ctttcccggc tttctgccta tcgcctgcgt gaagcccagg
    43441 ctgaaggcca atattgtact gccgaggtag ccatcgcact gttagatatg gccggcgata
    43501 ccggggcggc ggcagggtta ggcgagcatt ttacccgctt taaaacacgc tatctggcag
    43561 gaaaaacgca acatctgggt agcatcacag cagaacagtt agaaagcgtt taaaatcatt
    43621 cggtcacttc tgcgggagac cggtatgagt cagcgaggac tggaagcact actgcgacca
    43681 aaatcgattg cggtaattgg cgcatcgatg aaacccaatc gcgcaggtta cctgatgatg
    43741 cgtaacctgc tggcgggagg ctttaacgga ccggtactcc cggtgacgcc tgcctggaaa
    43801 gcggtgttgg gtgtgttggc ctggccggat attgccagct tgccctttac acccgacctt
    43861 gcggttttat gtaccaatgc cagccgtaat cttgctcttc tggaagagct cggcgagaaa
    43921 ggctgtaaaa cctgcattat tctttccgcc ccggcatcgc aacacgaaga tctccgcgcc
    43981 tgcgccctgc gccataacat gcgcctgcta ggaccaaaca gtctgggttt actggctccc
    44041 tggcaaggtc taaatgccag cttttcacct gtgccgatta aacgcggcaa actggcgttt
    44101 atttcgcaat cggctgccgt ctccaacacc atcctcgact gggcgcaaca gcgtgagatg
    44161 ggcttttcct actttattgc gctcggcgac agcctggata tcgacgttga tgaattgctc
    44221 gactatctgg cgcgcgacag taaaaccagc gccatcctgc tctatctcga acagttaagc
    44281 gacgcgcgac gctttgtttc ggcggcccgt agtgcctctc gcaataaacc gattctggtg
    44341 attaaaagcg gacgtagccc ggcggctcaa cgtctgttga acaccacggc aggaatggat
    44401 ccggcgtggg atgcggctat tcagcgtgcc ggtttgttgc gggtacagga tactcacgag
    44461 ctgttttcgg cagtggaaac cctcagccat atgcgcccac tgcgtggcga ccggctgatg
    44521 attatcagca acggtgctgc gcctgccgcg ctggcgctgg atgccttatg gtcacgcaat
    44581 ggcaagctgg caacgctaag cgaagaaacc tgccagaaac tgcgcgatgc actgccagaa
    44641 catgtggcaa tctctaaccc gctcgatcta cgcgatgacg ccagcagcga gcattatgtc
    44701 aaaacgctgg acattctgct ccacagccag gattttgatg cgctgatggt tattcattcg
    44761 cccagcgccg ctgctcccgc aacagaaagc gcgcaagtat taattgaagc ggtaaagcat
    44821 catccccgca gcaagtatgt ttctctgctg acgaactggt gtggcgaaca ttcctcgcaa
    44881 gaggcacgac gattattcag cgaagccggg ctgccgacct accgtacccc ggaaggaacc
    44941 atcactgctt ttatgcatat ggtggagtac cggcgtaatc agaagcaact acgcgaaacg
    45001 ccggcgttgc ccagcaatct gacctccaat accgcagaag cgcatcttct gttgcaacag
    45061 gcgattgccg aaggagcaac gtcactcgat acccatgaag ttcagcccat cctgcaagca
    45121 tatggcatga acacgctccc cacctggatt gccagcgata gcaccgaagc ggtgcatatt
    45181 gccgaacaga ttggttatcc ggtggcgctg aaattgcgtt cgccggatat tccacataaa
    45241 tcggaagttc agggcgtaat gctctacctg cgtacagcta atgaagtcca gcaagcggca
    45301 aacgctattt tcgatcgcgt aaaaatggcc tggccgcagg cgcggatcca cggcctgttg
    45361 gtgcaaagta tggctaaccg tgctggcgct caggagttgc gggttgtggt tgagcacgat
    45421 ccggttttcg ggccgttgat catgctgggc gaaggcggtg tggagtggcg tcctgaagat
    45481 caagccgtcg tcgcactacc gccgctgaac atgaacctgg cccgctatct ggttattcag
    45541 gggatcaaaa gtaaaaagat tcgtgcgcgc agtgcgctac gcccattaga tgttgcaggc
    45601 ttgagccagc ttctggtgca ggtttctaac ttgattgtcg attgcccgga aattcagcgt
    45661 ctggatattc atcctttgct ggcttctggc agtgaattta ccgcgctgga tgtcacgctg
    45721 gatatcgcgc cgtttgaagg cgataacgag agtcggctgg cagtgcgccc ttatccgcat
    45781 cagctggaag aatgggtaga attgaaaaac ggtgaacgct gcttgttccg cccgattttg
    45841 ccagaagatg agccacaact tcagcaattc atttcgcgag tcaccaaaga agatctttat
    45901 taccgctact ttagcgagat caacgaattt acccatgaag atttagccaa catgacgcag
    45961 atcgactacg atcgggaaat ggcatttgta gcggtacgac gtattgatca aacggaagag
    46021 atccttggcg tcacgcgtgc gatctccgac cctgataaca tcgatgccga atttgccgtg
    46081 ctggttcgct cggatctcaa agggttaggc ttaggtcgac gcttaatgga aaagttgatt
    46141 acctatacgc gagatcacgg actgcaacgt ctgaatggta ttacgatgcc aaacaatcgt
    46201 ggcatggtgg cgctggcccg caagctcggg tttaacgttg atatccagct cgaagagggg
    46261 atcgttgggc ttacgctaaa tcttgcccag cgcgaggaat catgagtaag gtactggaaa
    46321 tgttgaccac ttaatcggga ctggtgttat tattgcccgc ttatgtcgtc tgcattgcac
    46381 agaggaccct tcaatgaaca gagaagaaat gcactgtgat gttgtcaaaa tttaagcgta
    46441 ataaacatca acaacacctt gcccaactac ccaagatttc tcaatcagtt gatgatgtcg
    46501 atttctttta cgctcccgcc gacttccggg agacgctgct ggaaaaaata gccagcgcga
    46561 agcagcgcat ttgcattgtc gccctgtatc tcgaacagga tgacggtggc aaaggcattc
    46621 tgaacgcgtt gtatgaggct aaaaggcagc gtccggaact ggatgtgcgg gtgctggtcg
    46681 actggcatcg tgcacaacgt ggacgcattg gcgctgcggc atctaacact aacgctgact
    46741 ggtactgccg catggcgcag gaaaatccgg gcgtagatgt tccggtttat ggcgttccaa
    46801 tcaatacccg tgaagccctt ggtgttctgc actttaaagg ctttatcatc gacgatagcg
    46861 tactttatag cggtgccagc ctgaacgatg tttacctgca tcagcacgat aaatatcgct
    46921 acgaccgtta tcatcttatc cgtaaccgta agatgtcaga cattatgttt gaatgggtta
    46981 cacagaatat tatgaatggc cgcggcgtta atcgtctgga tgatgttaat cggccaaaaa
    47041 gcccggaaat caagaacgat attcgtctgt tccgccagga gctgcgtgat gccgcttatc
    47101 atttccaggg cgatgccgac aacgatcagc tttccgtaac gccgttggta ggtctgggga
    47161 aatcgagtct gttgaacaag accattttcc atcttatgcc ttgtgccgag cagaaactaa
    47221 ccatctgcac accttacttc aacctgccag caatccttgt gcgcaatatt atccagttgc
    47281 tgcgcgaagg gaaaaaggtc gaaattattg ttggtgataa aaccgcgaat gacttctaca
    47341 ttccggaaga tgaacctttc aagataattg gcgcattgcc ttatctctat gagatcaatc
    47401 tgcgtcgttt cctgagccgt ttgcagtatt acgtcaacac tgaccagtta gtggttcggt
    47461 tatggaaaga tgacgacaac acctatcacc tgaaagggat gtgggttgat gataagtgga
    47521 tgttgatcac tggtaataac ctgaacccgc gcgcctggcg tctggatctg gaaaacgcta
    47581 ttttgatcca cgatccgcaa ctggagcttg cgccacagcg agagaaagaa ctggagctga
    47641 tccgcgagca taccaccatc gttaagcact atcgcgacct gcaaagtatt gccgattatc
    47701 cggtgaaggt tcgtaaactc atccgtcgtt tgcgccgtat ccgcatcgac cgattaatta
    47761 gccgcatcct gtaatcacaa ccccgtcctg tgcggggttt gttttttgga ggccacgttt
    47821 tgcgtattct ttttgtctgt tcgctattat tactttctgg atgcagccat atggctaacg
    47881 atagctggag cgggcaggat aaagctcaac actttatcgc ctcggcgatg ctttccgccg
    47941 ccggaaatga atatgcacag catcagggga tgagtcgcga tcgcagtgcc actttcgggc
    48001 tgatgttctc tgttgggctg ggggcgtcaa aagaactttg ggatagccgc cccgagggga
    48061 gcggctggag ctggaaagat tttacctggg atgtcgccgg tgcaactact ggctataccg
    48121 tctggcaact gacccgtcac taaagacgca tccccttccc tttgcgatgt agcatcaaag
    48181 aaaccagaaa cgccaccacg gccatcaagg tcacatacca gaagaaggct gtttccattc
    48241 ctattgattt cagcgacaac gctacgtact ccgccgaacc accaaatata gcattggcga
    48301 ccgcatatga cagaccaaca cctaatgcac gaacctgtgc cgggaacatc tcagccttca
    48361 gtattccact gattgaagta taaaaactca cgatcagcag ggcacacatc accagaccaa
    48421 aagcggcata aggcgaggaa acgttttgca atgctgagag aataggaacg gtaaaaatgg
    48481 ctgccagaga accgaaacat aacattgagg tacgacgacc aatcttatcc gacagcgcgc
    48541 caatgagtgg ttgaataagc atgaatacaa acaatgcggc agtcataatg ccactcgcca
    48601 cgttggcatg cattcccgca gtatttacca gatacttctg catataagtg gtgaaggtat
    48661 agaaacaaag ggagcccgca gcggtaaaac cgagaaccat gatgaatgca cggcgattgc
    48721 gccataatcc tttcagagat ccagcttctt ttaaagcgcg tgtttcttgt tgtgaagttt
    48781 catctaactg acgacgtaac cacaacgcca caacagctaa cacagctcct aacgcgaaag
    48841 gaatacgcca tccccactct ctgagtgcag cgtcttccat ggtgtgttgt aaaaccacga
    48901 caaccagtag agctagcagt tgcccgccga tcaacgtcac atactgaaat gatgcgtaaa
    48961 aacctttgcg cccttcaacg gcaacttcac tcatataggt ggcgctggtg ccatattctc
    49021 cgccaacgga taatccctgg aataaacgag caagaagcaa taatgccgga gcccaggtac
    49081 cgattgtttc gtagcctggc aaacaggcga taaccagtga gccgaaacac atcatacaca
    49141 ccgataacag catcgatttt ttgcgaccat gtttatcggc tatgcggcca aatagccaac
    49201 cgcctattgg gcgcatcaga aatcccgcag caaaaacacc tgctgtttgc agtagttgag
    49261 tcgtcgtgtt cccggaaggg aagaagatgt gagcgaagta gagtgaacag aacgagtaga
    49321 catagaaatc gaaccactcg accagattac ctgaagaggc ccccacaatt gcccaaatgc
    49381 ggcgacgagt atcactactt gtcagtttgc tgtctgccgt tacagtactt tcagccatgc
    49441 cattatgtct cctgccgtaa tccgatgctt ttgtcggtcg cttttgttta tttcttttgg
    49501 taaagaaaat gttatacatt tgttgcatat catcatgcaa ccttaaccac gaatttagtt
    49561 agcaggaaaa tggttattga ggagcttaag gataaatttc tggtaaggag gacacgtatg
    49621 gaggtgggca agttggggaa gccgtattcg ctggcgtatg tggaggaata agctgccccc
    49681 tatcgtgcct gcgtaagctg gataagacgc gccatgaact gaaccccaaa acctggacag
    49741 tttcagttaa ccggcttttt gatactcagt ccggtattct accgg
//
LOCUS       DACAOP010000023        49296 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.023, whole genome shotgun sequence.
ACCESSION   DACAOP010000023 DACAOP010000000
VERSION     DACAOP010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49296
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.023"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..531
                     /gene="tnpB"
                     /locus_tag="IT892_001510"
     CDS             <1..531
                     /gene="tnpB"
                     /locus_tag="IT892_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAP3134741.1"
                     /translation="NWQKQERKIQRLHSRIANIRRDYLHKVTTTVSKNHAMIVIEDLK
                     VSNMSKSAAGTVSQPGRNVRAKSGLNRTILDQGWYEMRRQLEYKQLWRGGQVLAVPPA
                     YTSQRCACCGHTAKENRLSQSKFRCQACGYTANADVNGARNILAAGHAVLACGEMVQS
                     GRSLKQEPTEMIQATA"
     gene            575..682
                     /locus_tag="IT892_001511"
                     /pseudo
     CDS             575..682
                     /locus_tag="IT892_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709992.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(666..1304)
                     /gene="ytfB"
                     /locus_tag="IT892_001512"
     CDS             complement(666..1304)
                     /gene="ytfB"
                     /locus_tag="IT892_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418627.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YtfB"
                     /protein_id="HAP3134742.1"
                     /translation="MPGRFELKPTLEKVWHAPDNFRFMDPLPPMHRRGIIIAAIVLVV
                     GFLLPSDDTPNAPVVTREAQLDIQSQSQPPTEEQLRAQLVTPQNDPDQVAPVAPEPIQ
                     EGQPEEQPQTTQTQPFQPDSGIDNQWRSYRVEPGKTMAQLFRDHGLPATDVYAMAQVE
                     GAGKPLSNLQNGQMVKIRQNASGVVTGLTIDTGNNQQVLFTRQPDGSFIRAR"
     gene            1523..2143
                     /locus_tag="IT892_001513"
     CDS             1523..2143
                     /locus_tag="IT892_001513"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313212.2"
                     /note="FKBP-type; rotamase; catalyzes the cis-trans
                     isomerization of proline imidic peptide bonds in
                     oligopeptides; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP3134743.1"
                     /translation="MTTPTFDTIEAQASYGIGLQVGQQLSESGLQGLLPEALVAGIAD
                     ALESKHPAVPVDVVHRALREIHERADAVRRQRFQAMAAEGVKYLEENAKKEGVNSTES
                     GLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIPGWIE
                     ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL"
     gene            2452..3864
                     /gene="cycA"
                     /locus_tag="IT892_001514"
                     /gene_synonym="dagA"
     CDS             2452..3864
                     /gene="cycA"
                     /locus_tag="IT892_001514"
                     /gene_synonym="dagA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine/D-alanine/glycine transporter"
                     /protein_id="HAP3134744.1"
                     /translation="MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMG
                     SGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYF
                     TGWTYWFCWVVTGMADVVAITAYAQFWFPDLSDWVASLAVIVLLLTLNLATVKMFGEM
                     EFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGF
                     QIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSV
                     VPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA
                     FAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILC
                     SYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVFVVVLLTLEDDTRQALLVTPLWF
                     IALGLGWLFIGKKRAAELRK"
     gene            complement(3909..4571)
                     /gene="ytfE"
                     /locus_tag="IT892_001515"
     CDS             complement(3909..4571)
                     /gene="ytfE"
                     /locus_tag="IT892_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein YtfE"
                     /protein_id="HAP3134745.1"
                     /translation="MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARK
                     ELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVE
                     RVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEH
                     DEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALA
                     GE"
     gene            complement(4679..5644)
                     /locus_tag="IT892_001516"
     CDS             complement(4679..5644)
                     /locus_tag="IT892_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709987.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HAP3134746.1"
                     /translation="MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLI
                     ALPIAWLGRVRLRQLARRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLP
                     VVIPVFANLLYSQRDGKLAWGKLAPALICIGIGLACVNIAELNHGLPDFDWARYTSGI
                     VLALVSVVCWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNIQ
                     TPDFSLPFGPRPLVFISLMVAIAVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGL
                     LYTFLIRQQMPPLMTLSGIALLVVGVVIAVRAKPEKPLTESVSES"
     gene            complement(5753..6613)
                     /gene="qorB"
                     /locus_tag="IT892_001517"
     CDS             complement(5753..6613)
                     /gene="qorB"
                     /locus_tag="IT892_001517"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313217.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HAP3134747.1"
                     /translation="MIAITGATGQLGHYVIKSLMKTVPASQIVAIVRNPAKAQALTAQ
                     GITVRQADYGDEAALTSALQGVEKLLLISSSEVGQRAPQHRNVINAAKTAGVKFIAYT
                     SLLHADKSPLGLADEHIETEKMLADSGIVYTLLRNGWYTENYLASAPAALEHGVFIGA
                     AGDGKIASATRADYAAAAARVISEAGHEGKVYELAGDSAWTLTQLAAELTKQSGKQVT
                     YQNLSETDFAAALKSVGLPDGLADMLADSDVGASKGGLFDDSKTLSKLIGRPTTTLAE
                     SVSHLFNVNN"
     gene            6702..7082
                     /locus_tag="IT892_001518"
     CDS             6702..7082
                     /locus_tag="IT892_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418633.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP3134748.1"
                     /translation="MSQVSLSQQLKEGNLFAEQCPSREVLKHVTSRWGVLILVALREG
                     THRFSDLRRKIGGVSEKMLAQSLQALEQDGFLNRIAYPVVPPHVEYSLTPLGEQVSEK
                     VAALADWIELNLPEVLAVRDERAA"
     gene            complement(7205..9148)
                     /gene="cpdB"
                     /locus_tag="IT892_001519"
     CDS             complement(7205..9148)
                     /gene="cpdB"
                     /locus_tag="IT892_001519"
                     /EC_number="3.1.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2',3'-cyclic-nucleotide 2'-phosphodiesterase"
                     /protein_id="HAP3134749.1"
                     /translation="MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKD
                     TATEKFGLVRTASLINDARNEVKNSVLVDNGDLIQGSPLADYMSAKGLKAGDVHPVYK
                     ALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDT
                     EVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGAD
                     VVVVLAHSGLSADPYKVMAENSVYYLSEIPGVNAIMFGHAHAVFPGKDFADIEGADIA
                     KGTLNGVPAVMPGMWGDHLGVVDLQLSNNSGKWQVTQAKAEARPIYDIANIKSLAAED
                     SKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQ
                     GDPDLAKLPVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKAS
                     GKEVKEWLECSAGQFNQIDPDNTKPQSLINWDGFRTYNFDVIDGVNYQIDVTQPARYD
                     GECQMVNANAERIKNLTFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIAFASPDE
                     NRSVLAAWIADESKRAGEIHPAADNNWRLAPIAGDKKLDIRFETSPSDKAAAFIKEKG
                     QYPMNKVATDDIGFAIYQVDLSK"
     gene            9338..10078
                     /gene="cysQ"
                     /locus_tag="IT892_001520"
     CDS             9338..10078
                     /gene="cysQ"
                     /locus_tag="IT892_001520"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HAP3134750.1"
                     /translation="MLDQVCQLARNAGDAIMQVYDGTKPMDVVSKADNSPVTAADIAA
                     HTVIMDGLRTLTPDIPVLSEEDPPGWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNI
                     ALIDHGKPILGVVYAPVMNVMYSAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHAD
                     AELKEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTNIWDTAAGHAVAAAAGA
                     HVHDWQGKPLDYTPRESFLNPGFRVSIY"
     gene            10445..11227
                     /locus_tag="IT892_001521"
     CDS             10445..11227
                     /locus_tag="IT892_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134751.1"
                     /translation="MREFFRCATQIDKDSYQVLSSKNETVNAMDKFLISFSLKDNGAE
                     YTMTLRGSGFEYEEIPITINEYNSFMDFKNREFPLEQNRRLYAWDILQKKQSDIPKRI
                     KGYIHQAIGDVSLGYALLEDIVSKLKRGKFELQIPGGGIKECDGWYIYEKIIDDNFAI
                     VIESLGFALKIYGGDERFRNGSSVVLEDEDYSLIYNFLVNAGCQQVELAEQVDAIVSA
                     NLAADSNITKEKICEKYKSTIEAFKKEQLALPVLVRRKNSYT"
     gene            complement(11290..11844)
                     /locus_tag="IT892_001522"
     CDS             complement(11290..11844)
                     /locus_tag="IT892_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HAP3134752.1"
                     /translation="MTLRKILVLTCLLLPMMASAHQFETGQRVPPIGITDRGELVLDK
                     DQFSYKTWNSAQLVGKVRVLQHIAGRTSAQEKNATLIEAIKSAKLPHDRYQTTTIVNT
                     DDAIPGSGMFVRSSLESNKKLYPWSQFIVDSNGVARGAWQLDEESSAVVVLDKDGRVQ
                     WAKDGALTQEEVQQVMDLLQKLLK"
     gene            12169..12375
                     /locus_tag="IT892_001523"
     CDS             12169..12375
                     /locus_tag="IT892_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1107 domain-containing protein"
                     /protein_id="HAP3134753.1"
                     /translation="MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKV
                     KDKLHLSVMSEVNRQVMRLQTEMA"
     gene            complement(12437..13780)
                     /locus_tag="IT892_001524"
     CDS             complement(12437..13780)
                     /locus_tag="IT892_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP3134754.1"
                     /translation="MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINA
                     QRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFHSLFSRYMSAELSEQLSF
                     ILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANI
                     IFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTP
                     RENVIWFDLHEDEQSLKNKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLA
                     LNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMG
                     DLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRK
                     IPKRTDSVKFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA"
     gene            complement(14103..14741)
                     /gene="msrA"
                     /locus_tag="IT892_001525"
     CDS             complement(14103..14741)
                     /gene="msrA"
                     /locus_tag="IT892_001525"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP3134755.1"
                     /translation="MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGME
                     IAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYD
                     PSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAA
                     MLAADDDRRITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA"
     gene            14947..16680
                     /gene="tamA"
                     /locus_tag="IT892_001526"
     CDS             14947..16680
                     /gene="tamA"
                     /locus_tag="IT892_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamA"
                     /protein_id="HAP3134756.1"
                     /translation="MRYIRQLCCVSLLCLSGSAVAANVRLQVEGLSGQLEKNVRAQLS
                     TIESDEVTPDRRFRARVDDAIREGLKALGYYQPTIEFDLRPPPKKGRQVLIAKVTPGV
                     PVLIGGTDVVLRGGARTDKDYLKLLDTRPAIGTVLNQGDYENFKKSLTSIALRKGYFD
                     SEFTKAQLGIALGLHKAFWDIDYNSGERYRFGHVTFEGSQIRDEYLQNLVPFKEGDEY
                     ESKDLAELNRRLSATGWFNSVVVAPQFDKARETKVLPLTGVVSPRTENTIETGVGYST
                     DVGPRVKATWKKPWMNSYGHSLTTSTSISAPEQILDFSYKMPLLKNPLEQYYLVQGGF
                     KRTDLNDTESDSTTLVASRYWDLSSGWQRAINLRWSLDHFTQGEITNTTMLFYPGVMI
                     SRTRSRGGLMPTWGDSQRYSIDYSNTAWGSDVDFSVFQAQNVWIRTLYDRHRFVTRGT
                     LGWIETGDFDKVPPDLRFFAGGDRSIRGYKYKSIAPKYANGDLKGASKLITGSLEYQY
                     NVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWESPVGPIKLDFAVPVADKDEHG
                     LQFYIGLGPEL"
     gene            16677..20456
                     /gene="tamB"
                     /locus_tag="IT892_001527"
     CDS             16677..20456
                     /gene="tamB"
                     /locus_tag="IT892_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamB"
                     /protein_id="HAP3134757.1"
                     /translation="MSLWKKISLGVVIVILLLLGSVAFLVGTTSGLHLVFKAADRWVP
                     GLDVGKVTGGWRDLTLSDVRYEQPGVAVKAGNLHLAVGLECLWNSSVCINDLALKDIQ
                     VNIDSKKMPPSEQVEEEEDSGPLDLSTPYPITLTRVALDNVNIKIDDTTVSVMDFTSG
                     LNWQEKTLTLKPTSLKGLLIALPKVAEVAQEEVVEPKIENPQPEEKPLGETLKDLFSR
                     PVLPEMTDVHLPLNLNIEEFKGEQLRVTGDTDITVSTMLLKVSSIDGNTKLDALDIDS
                     SQGIVNASGTAQLSDNWPVDITLNSTLNVEPLKGEKVKLKVGGALREQLEIGVNLSGP
                     VDMDLRAQTRLAEAGLPLNVEVNSKQIYWPFTGEKQYQADDLKLKLTGKMTDYTLSMR
                     TAVKGLEIPPATITLDAKGNEQQVNLDKLTVAALEGKTELKALLDWQQAISWRGELTL
                     NGINTAKEIPEWPSKLNGLIKTRGSLYGGTWQMEVPELKLTGNVKQNKVNVDGTLKGN
                     SYMQWMIPGLHLELGPNSAEVKGELGVKDLNLDATINAPGLDNALPGLGGTAKGLVKV
                     RGTVEAPQLLADITARGLRWQELSVAQVRVEGDIKSTDQIAGKLDVRVEQISQPDVNI
                     NLVTLNAKGSEKQHELQLRIQGEPVSGQLNLAGSFDRKEERWKGTLSNTRFQTPVGPW
                     SLTRDIALDYRNKEQKISIGPHCWLNPNAELCVPQTIDAGAEGRAVVNLNRFDLAMLK
                     PFMPETTQASGIFTGKADVAWDTTKEGLPQGSITLSGRNVQVTQTVNDAALPVAFQTL
                     NLTAELRNNRAELGWTIRLTNNGQFDGQVQVTDPQGRRNLGGNVNIRNFNLAMINPIF
                     TRGEKAAGMVSANLRLGGDVQSPQLFGQLQVTGVDIDGNFMPFDMQPSQLAVNFNGMR
                     STLAGTVRTQQGEIYLNGDADWSQIENWRARVTAKGSKVRITVPPMVRMDVSPDVVFE
                     ATPNLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNDNLQPEEPKTASIPINSNL
                     IVHVGNNVRIDAFGLKARLTGDLNVVQDKQGLGLNGQINIPEGRFHAYGQDLIVRKGE
                     LLFSGPPDQPYLNIEAIRNPDATEDDVIAGVRVTGLADEPKAEIFSDPAMSQQAALSY
                     LLRGQGLESDQSDSAAMTSMLIGLGVAQSGQIVGKIGETFGVSNLALDTQGVGDSSQV
                     VVSGYVLPGLQVKYGVGIFDSIATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF"
     gene            20459..20800
                     /locus_tag="IT892_001528"
     CDS             20459..20800
                     /locus_tag="IT892_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HAP3134758.1"
                     /translation="MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGA
                     VPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLKL
                     IESGDWLDRDK"
     gene            21012..21263
                     /locus_tag="IT892_001529"
     CDS             21012..21263
                     /locus_tag="IT892_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ChpS family
                     antitoxin"
                     /protein_id="HAP3134759.1"
                     /translation="MRITIKRWGNSAGMVIPNIVMKELNLQPGQSVEAQVSNNQLILT
                     PISRRYSLDELLAQCDMNAAELSEQDVWGKSTPAGDEIW"
     gene            21257..21607
                     /gene="chpB"
                     /locus_tag="IT892_001530"
     CDS             21257..21607
                     /gene="chpB"
                     /locus_tag="IT892_001530"
                     /EC_number="4.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease toxin ChpB"
                     /protein_id="HAP3134760.1"
                     /translation="MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLG
                     MTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLVNQVRMMDLRARLAKRIGLAADE
                     VVEEALLRLQAVVE"
     gene            complement(21687..22217)
                     /gene="ppa"
                     /locus_tag="IT892_001531"
     CDS             complement(21687..22217)
                     /gene="ppa"
                     /locus_tag="IT892_001531"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HAP3134761.1"
                     /translation="MSLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDR
                     FMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGE
                     DAKLIAVPHTKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWVKVEGWENAE
                     AAKAEIVASFERAKNK"
     gene            22527..23483
                     /gene="ytfQ"
                     /locus_tag="IT892_001532"
     CDS             22527..23483
                     /gene="ytfQ"
                     /locus_tag="IT892_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter
                     substrate-binding protein YtfQ"
                     /protein_id="HAP3134762.1"
                     /translation="MWKRLLVVSAVSAAMSSMALAAPLTVGFSQVGSESGWRAAETNV
                     AKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEAKD
                     AEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVG
                     ASVAIDRKKGFAEAIKNAPNIKIIRSQSGDFTRSKGKEVMESFIKAENNGKNICMVYA
                     HNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPDIYKAMIDGEANASVELTPNMAGPA
                     FDALEKYKKDGTMPEKLTLTKSTLYLPDTAKEELEKKKNMGY"
     gene            23623..25125
                     /locus_tag="IT892_001533"
     CDS             23623..25125
                     /locus_tag="IT892_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAP3134763.1"
                     /translation="MTTDQHQEILRTEGLSKFFPGVKALDNVDFSLRRGEIMALLGEN
                     GAGKSTLIKALTGVYHADRGTIWLEDQAISPKNTAHAQQLGIGTVYQEVNLLPNMSVA
                     DNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVREPLNRFSVAMQQIVAICRAI
                     DLSAKVLILDEPTASLDTQEVELLFGLMRQLRDRGVSLIFVTHFIDQVYQVSDRITVL
                     RNGSFVGCRETRELPQIELVKMMLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTI
                     APFDLEVRPGEIVGLAGLLGSGRTETAEVIFGIKPADSGTVLIKGKPQTLRSPHQASV
                     LGIGFCPEDRKTDGIIAAASVRENIILALQAQRGWLRPISRKEQQEIAERFIRQLGIR
                     TPSTEQPIEFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCA
                     DGLALLVISSELEELVGYADRVIIMRDRKQVAEIPLAELSVPAIMNAIAA"
     gene            25139..26161
                     /locus_tag="IT892_001534"
     CDS             25139..26161
                     /locus_tag="IT892_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3134764.1"
                     /translation="MPQSLPDTTTPKRRFRWPTGMPQLVALLLVLLVDSLVAPHFWQV
                     VLQDGRLFGSPIDILNRAAPVALLAIGMTLVIATGGIDLSVGAVMAIAGATTAAMTVA
                     GFSLPIVLLSALGTGILAGLWNGILVAILKIQPFVATLILMVAGRGVAQLITSGQIVT
                     FNSPDLSWFGSGSLLFLPTPVIIAVLTLILFWLLTRKTALGMFIEAVGINIRAAKNAG
                     VNTRIIVMLTYVLSGLCAAIAGIIVAADIRGADANNAGLWLELDAILAVVIGGGSLMG
                     GRFNLLLSVVGALIIQGMNTGILLSGFPPEMNQVVKAVVVLCVLIVQSQRFISLIKGV
                     RSRDKT"
     gene            26148..27143
                     /gene="yjfF"
                     /locus_tag="IT892_001535"
     CDS             26148..27143
                     /gene="yjfF"
                     /locus_tag="IT892_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease YjfF"
                     /protein_id="HAP3134765.1"
                     /translation="MIKRNLPLMITIGVFVLGYLYCLTQFPGFASTRVICNILTDNAF
                     LGIIAVGMTFVILSGGIDLSVGSVIAFTGVFLAKVIGDFGLSPLLAFPLVLVMGCAFG
                     AFMGLLIDALKIPAFIITLAGMFFLRGVSYLISEESIPINHPVYDTLSSLAWKIPGGG
                     RLSAMGLLMLAVVVIGIFLAHRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLST
                     GLATLAGIVFSIYTQAGYALAGVGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQG
                     LIQTYINFDGTLSSWWTKIAIGILLFIFIALQRGLTVLWENRQSSPVTRVNIAQR"
     gene            complement(27176..28174)
                     /gene="fbp"
                     /locus_tag="IT892_001536"
     CDS             complement(27176..28174)
                     /gene="fbp"
                     /locus_tag="IT892_001536"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HAP3134766.1"
                     /translation="MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAG
                     LVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEH
                     AKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
                     YGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVK
                     KYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYEC
                     NPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA"
     gene            28350..29723
                     /gene="mpl"
                     /locus_tag="IT892_001537"
     CDS             28350..29723
                     /gene="mpl"
                     /locus_tag="IT892_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HAP3134767.1"
                     /translation="MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEK
                     QGIELIQGYDASQLDPQPDLVIIGNAMTRGNPCVEAVLEKNIPYMSGPQWLHDFVLRD
                     RWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSARLGESNFFVIEAD
                     EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRII
                     WPENDINLKQTMAMGCWSEQELVGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLV
                     GEHNMHNGLMAIAAARHVGIAPADAANALGSFINARRRLELRGEANGVTVYDDFAHHP
                     TAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHI
                     PWQVAEVAEACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLA
                     KKAEAAQ"
     gene            complement(29879..30430)
                     /locus_tag="IT892_001538"
     CDS             complement(29879..30430)
                     /locus_tag="IT892_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein"
                     /protein_id="HAP3134768.1"
                     /translation="MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGA
                     EIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALD
                     KLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKE
                     GNKPPKSARQIFQYLRELAENEG"
     gene            30524..31876
                     /gene="pmbA"
                     /locus_tag="IT892_001539"
     CDS             30524..31876
                     /gene="pmbA"
                     /locus_tag="IT892_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HAP3134769.1"
                     /translation="MALAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTT
                     GISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARY
                     TSPDPCAGVADKELLAFEAPDLDLFHPAEVSPDEAIELAARAEQAALQADKRITNTEG
                     GSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMSDLQT
                     PEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGAVYRKSTFL
                     LDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIKDGILTQWLLTSYSA
                     RKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMGQGVSAITGDYSRGA
                     AGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIETRSNIQCGSVLLPEMKIAGQ
                     "
     gene            31931..32317
                     /gene="cybC"
                     /locus_tag="IT892_001540"
     CDS             31931..32317
                     /gene="cybC"
                     /locus_tag="IT892_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313240.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HAP3134770.1"
                     /translation="MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDTLKVVEKADN
                     AAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
                     EGKVKEAQAAAEQLKTTRNAYHQKYR"
     gene            complement(32362..32826)
                     /gene="nrdG"
                     /locus_tag="IT892_001541"
     CDS             complement(32362..32826)
                     /gene="nrdG"
                     /locus_tag="IT892_001541"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate
                     reductase-activating protein"
                     /protein_id="HAP3134771.1"
                     /translation="MNYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRVNSG
                     QPFTKAMEDQIINDLNDTRIKRQGISLSGGDPLHPQNVPDILKLVKRIRAECPDKDIW
                     VWTGYKLDDLNAAQMQVVDLINVLVDGKFVQNLKDPSLIWRGSSNQVVHHLR"
     gene            complement(32986..35124)
                     /gene="nrdD"
                     /locus_tag="IT892_001542"
     CDS             complement(32986..35124)
                     /gene="nrdD"
                     /locus_tag="IT892_001542"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004128226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAP3134772.1"
                     /translation="MTPHVMKRDGCKVPFKSERIKEAILRAAKAAEVDDADYCATVAA
                     VVSEQMQGRNQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIEREKRGRLNQEI
                     RGLVEQTNASLLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
                     YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASH
                     IYGGTTINRIDEVLAPFVTASYNKHRKTAEEWSIPDAEGYANSRTIKECYDAFQSLEY
                     EVNTLHTANGQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGKNRKTAVFPKLVFAI
                     RDGLNHKKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWE
                     NENGEQIHDGRNNLGVISLNLPRIALEAKGDEATFWKLLDERLVLARKALMTRIARLE
                     GVKARVAPILYMEGACGVRLNADDDVSEIFKNGRASISLGYIGIHETINALFGGEHVY
                     DNEQLRAKGIAIVERLRQAVDQWKEETGYGFSLYSTPSENLCDRFCRLDTAEFGVVPG
                     VTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDV
                     WDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGFTCPKCGNHDASRVSVTRRVCGY
                     LGSPDARPFNAGKQEEVKRRVKHLGNGQIG"
     gene            complement(35518..37173)
                     /gene="treC"
                     /locus_tag="IT892_001543"
     CDS             complement(35518..37173)
                     /gene="treC"
                     /locus_tag="IT892_001543"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAP3134773.1"
                     /translation="MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHK
                     LGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMV
                     FNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
                     LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPEDLDGD
                     GRRFYTDGPRAHEFLHEMNRDVFTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFN
                     FHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFG
                     DEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFSRITDYRDVESLNMFAELR
                     NDGRDADELLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALA
                     DDSSVFYTYQKLIALRKQEAILTWGNYQDLLPNSPVLWCYRREWKGQTLLVIANLSRE
                     IQPWQPGKMRGNWQLVMHNYEEASPQPCAMTLRPFEAVWWLQK"
     gene            complement(37223..38644)
                     /gene="treB"
                     /locus_tag="IT892_001544"
     CDS             complement(37223..38644)
                     /gene="treB"
                     /locus_tag="IT892_001544"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HAP3134774.1"
                     /translation="MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANAR
                     PKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARQNMK
                     WHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFL
                     WLIGDAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDF
                     GMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHA
                     LIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQ
                     SMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGIN
                     LKYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAI
                     IIPIVLTSFIYQRKYRLGTLDIV"
     gene            complement(38763..39710)
                     /gene="treR"
                     /locus_tag="IT892_001545"
     CDS             complement(38763..39710)
                     /gene="treR"
                     /locus_tag="IT892_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator TreR"
                     /protein_id="HAP3134775.1"
                     /translation="MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSQRTRERVEAVMN
                     QHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQF
                     SPQLVAEHLGVLKRRNIDGVVLFGFTGITEEMLAHWQSSLVLLARDAKGFASVCYDDE
                     GAIKILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKLHPVAALPGLAM
                     KQGYENVAKVITPETTALLCATDTLALGASKYLQEQRIDTLQLASVGNTPLMKFLHPE
                     IVTVDPGYAEAGRQAACQLIAQVTGRSEPQQIIIPATLS"
     gene            39895..39948
                     /gene="mgtL"
                     /locus_tag="IT892_001546"
     CDS             39895..39948
                     /gene="mgtL"
                     /locus_tag="IT892_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003933616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mgtA regulatory leader peptide MgtL"
                     /protein_id="HAP3134776.1"
                     /translation="MEPDPTPLPRRRLKLFR"
     gene            40089..42785
                     /gene="mgtA"
                     /locus_tag="IT892_001547"
     CDS             40089..42785
                     /gene="mgtA"
                     /locus_tag="IT892_001547"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAP3134777.1"
                     /translation="MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTAVPPSLSAHCLK
                     MAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENKLPAQQPSPWWVHLWVCYRNPFN
                     ILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
                     RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLP
                     VEKAATTRQPEHSNPLECDTLCFMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQES
                     EPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALFALSVAVGLTPEMLP
                     MIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDIS
                     GKTSERVLHSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERR
                     RMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQ
                     GLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKASGITVK
                     ILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKER
                     IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLE
                     EGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVS
                     QVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPET
                     QTLFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPL
                     ASYLQLQALPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ"
     gene            complement(42991..43377)
                     /gene="ridA"
                     /locus_tag="IT892_001548"
     CDS             complement(42991..43377)
                     /gene="ridA"
                     /locus_tag="IT892_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="HAP3134778.1"
                     /translation="MSKTIATENAPAAIGPYVQGVDLGNMIITSGQIPVNPKTGEVPA
                     DVAAQARQSLDNVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNATF
                     PARSCVEIARLPKDVKIEIEAIAVRR"
     gene            complement(43450..43911)
                     /gene="pyrI"
                     /locus_tag="IT892_001549"
     CDS             complement(43450..43911)
                     /gene="pyrI"
                     /locus_tag="IT892_001549"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HAP3134779.1"
                     /translation="MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITI
                     GLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPER
                     IDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN"
     gene            complement(43924..44859)
                     /gene="pyrB"
                     /locus_tag="IT892_001550"
     CDS             complement(43924..44859)
                     /gene="pyrB"
                     /locus_tag="IT892_001550"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HAP3134780.1"
                     /translation="MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKV
                     IASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDA
                     IVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAM
                     VGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIVWSLHSSIEE
                     VMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIAT
                     DVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL"
     gene            complement(44863..44997)
                     /gene="pyrL"
                     /locus_tag="IT892_001551"
     CDS             complement(44863..44997)
                     /gene="pyrL"
                     /locus_tag="IT892_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyr operon leader peptide"
                     /protein_id="HAP3134781.1"
                     /translation="MVQCVRHFVLPRLKKDAGLPFFFPLITHSQPLNRGAFFCPGVRR
                     "
     gene            complement(45278..45673)
                     /locus_tag="IT892_001552"
     CDS             complement(45278..45673)
                     /locus_tag="IT892_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HAP3134782.1"
                     /translation="MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGT
                     PEPDFQQQVRLAFDNLHATLAAAGCTFDDIIDVTSFHTDPEKQFEDIMTVKNEIFSAP
                     PYPNWTAVGVTWLAGFDFEIKVIARIPAQ"
     gene            complement(45804..46517)
                     /gene="bdcA"
                     /locus_tag="IT892_001553"
     CDS             complement(45804..46517)
                     /gene="bdcA"
                     /locus_tag="IT892_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP3134783.1"
                     /translation="MGAFTGKTVLILGGSRGIGAAIVRHFVTDGANVRFTYAGSKDAA
                     ERLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRL
                     FKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGL
                     ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHGFMAIKRHGQPEEVAGMVAWLAG
                     PEASFVTGAMHTIDGAFGA"
     gene            46588..47181
                     /locus_tag="IT892_001554"
     CDS             46588..47181
                     /locus_tag="IT892_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709951.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP3134784.1"
                     /translation="MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTD
                     YLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLADILLDDRPVGECLVEVLKEAAR
                     RYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFM
                     STVMSGLSAKAREGHSIEQLCATAALAGEAIKTILKE"
     gene            47326..47778
                     /locus_tag="IT892_001555"
     CDS             47326..47778
                     /locus_tag="IT892_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF386 domain-containing protein"
                     /protein_id="HAP3134785.1"
                     /translation="MIIGNIHNLQPWLPQELRQAIEHVKAHVTAETPKGKHDIEGNRL
                     FYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAF
                     LPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA"
     gene            47901..>49296
                     /locus_tag="IT892_001556"
     CDS             47901..>49296
                     /locus_tag="IT892_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134786.1"
                     /translation="MSKISDLNYSQHITLADNFKQKSEVLNTWRVGMNDFARNAEGQD
                     NTRNILDPKTFLEFLVKIFTLGYVDFSKRSNEAGRNMMAHIESSSYIKNNDGSEIMKF
                     VMNNPEGERADLSKVEIEITLSTITTMGTRQGHTAIIFPQPDGLTNRYEGKSFERKDE
                     SSLHLITNKVLACYQREANKEVALLLNNHQKLNYRQKLNNSQGLNNSQGLNNSQGLNN
                     SQELNDSQELNDSQDLNNSQVSCKGSVDSTITDLLEKPLNNALLAIRKEHLLLMPHVC
                     DESISYLLGEKGILEEIDKLYALNDHGIDNDKVGNNEINDIKVNLSHILIDSLDDAKV
                     NLTPVIDSILETFSKSPYINDVRILDWCFNKSMQYFGDSEKITHACSVMSHIDFDCNQ
                     SKIAETLFFNLDKEPYKNSRELQELIWEKLVAYVNVFNLSNQEKSRLILRLFDDVKLL
                     FNEVPVSILVNDIFL"
BASE COUNT        11958 a        12142 c        13047 g        12149 t
ORIGIN      
        1 aactggcaga agcaggaacg caaaatacag cgactgcatt cccgtatcgc aaatatccgc
       61 agggactacc ttcacaaagt cacaacgacc gtcagcaaaa accacgcaat gatagtcatt
      121 gaggatttga aggtcagcaa catgtcaaag tcagcagcgg gtacggtcag ccagccgggt
      181 cgcaatgtcc gggcaaaatc aggtttaaac cgtacgatac tggatcaggg ctggtatgaa
      241 atgcgccgcc agcttgagta caagcagctc tggcgtggcg gtcaggtgct tgctgttccg
      301 ccagcgtaca caagccagcg atgcgcgtgc tgtggtcata cagcgaaaga aaatcgcctg
      361 tcacaaagta aattcagatg ccaggcatgt ggatatacag cgaacgccga tgtaaatggc
      421 gctcgtaaca ttttagcggc ggggcacgcc gttcttgcct gtggagagat ggtgcagtca
      481 ggccgctcgt tgaagcagga acccaccgaa atgattcagg cgacagcctg aacgtagcag
      541 ggatccacgt ccttcagggc gtggaggatg tcaacatatc agtatggttt ccccccaggc
      601 actggaagcc agacgtaagg tcatcaaaga gacaatcctt agctggcttt tggttgaccc
      661 ttcatctacc gcgcacgaat aaaactgcca tccggctggc gggtgaacag gacctgttga
      721 ttattccccg tatcaatggt taagcccgtc accacgccgc tggcgttctg gcggattttc
      781 accatttgcc cgttttgcaa attactcagc ggcttacccg cgccttctac ctgcgccatt
      841 gcatagacat cggtagcggg cagtccgtgg tcgcggaaca gttgcgccat cgttttaccg
      901 ggttcgacac ggtaagagcg ccattgatta tcaattccgc tatctggctg gaatggttgc
      961 gtttgggtag tttgcggctg ctcttctggc tggccttcct gtataggttc tggagcgacc
     1021 ggagccacct gatcaggatc attttgtggg gtgactaatt gcgcccgcag ctgttcttct
     1081 gtcggcggtt gtgattgcga ctgaatatct aactgcgctt cacgcgtcac caccggcgcg
     1141 ttgggcgtat catcagatgg aagcagaaat ccgaccacca atacaatggc ggcaataatg
     1201 atcccccgac gatgcatcgg cggcagcggg tccatgaagc gaaaattgtc cggcgcgtgc
     1261 cagactttct ccagggttgg ttttagttca aagcgcccgg gcatggtttc ctcctgctcc
     1321 gcgtcttgtt cctcaatcat agcctatgaa taagctaacg ctatgatgtc cgtggtaaac
     1381 ccgcctttat tatattcata cgggatattg ctattgtttc tttttccccg ggatttgtca
     1441 tcattcctgc gacaaagttt tacccaaaga agtgtggctg atatgctgcc cgctactttt
     1501 ataccctaag aaaggaaata cgatgaccac cccaactttt gacaccatcg aagcgcaagc
     1561 aagctacggc attggtttac aggtaggcca acaactgagt gaatctggcc tgcaagggct
     1621 gctgccggag gcgctggtgg ctggtattgc agatgcgctg gaaagcaaac atccggctgt
     1681 tccggttgat gtggtgcatc gcgcgctgcg tgaaatccac gaacgcgccg atgccgttcg
     1741 tcgtcagcgt ttccaggcga tggctgccga aggtgtgaaa tatcttgaag aaaatgccaa
     1801 aaaagaaggt gtgaacagca ccgaatctgg cctgcaattc cgcgtgatca accagggtga
     1861 aggcgcaatt ccggcacgta ctgaccgcgt tcgtgttcat tacaccggta aactgatcga
     1921 cggcaccgtg tttgacagct ccgttgctcg tggtgaaccc gctgaattcc cggttaatgg
     1981 cgtgatccct ggctggattg aagcactgac tctgatgccg gtaggttcta aatgggaact
     2041 gactatcccg caggaactgg catatggcga gcgcggcgca ggcgcatcca tccctccgtt
     2101 cagcaccctg gtgtttgaag tcgaactgct ggaaatcctc taagcagcgc attctgttcc
     2161 cctcgaacca gaggggagca ggcattcagc aataaaccct tcagtttgcc aaacggcgct
     2221 attttgtgtt gcaaagaccc cgtaagcgtg tatttttgtg agctgtttcg cgttatcacc
     2281 gtgatatgac actcacttta aacataaaat taacattaga tctaaatctt agtattcatc
     2341 ccgcgtattg ttacctaata tcgatgagtc ccgatacaga ttcgtcgtat catagactga
     2401 ctaaaggccg tagagcctga acaacacaga caggtacagg aagaaaaaaa catggtagat
     2461 caggtaaaag tcgttgccga tgatcaggct ccggctgaac agtcgctacg gcgcaatctc
     2521 acaaaccgac atattcagct tattgccatt ggcggtgcca ttggtacggg gttgtttatg
     2581 gggtctggca aaacgattag ccttgccggg ccgtcgatca ttttcgttta tatgatcatc
     2641 ggttttatgc tctttttcgt gatgcgggca atgggggaat tgctgctttc gaatctggaa
     2701 tacaaatctt ttagtgactt cgcttccgat ttactcgggc cgtgggcagg atatttcacc
     2761 ggctggactt actggttctg ctgggttgta accggtatgg cagacgtggt ggcgatcact
     2821 gcttatgctc agttctggtt ccccgatctc tccgactggg tcgcctcgct ggcggtgata
     2881 gtgctgctgt tgacgctcaa ccttgccacc gtgaaaatgt tcggtgagat ggagttctgg
     2941 tttgcgatga tcaaaatcgt cgccatcgtg tcgctgattg tcgtcggcct ggtcatggtg
     3001 gcgatgcact ttcagtcacc gaccggtgtg gaagcgtcat tcgcgcattt gtggaatgac
     3061 ggcggctggt tcccgaaagg tttaagtggc ttctttgccg gattccagat agcggttttc
     3121 gctttcgtgg ggattgagct ggtaggtaca acagctgcgg aaaccaaaga tccggagaaa
     3181 tcactgccac gcgcgattaa ctccattccg atccgtatca ttatgttcta cgtcttcgcg
     3241 ctgattgtga ttatgtccgt gacgccgtgg agttcggtag tcccggagaa aagcccgttt
     3301 gttgaactgt tcgtgttggt agggctgcct gctgccgcaa gcgtgatcaa ctttgtggtg
     3361 ctgacctctg cggcgtcttc cgctaacagc ggcgtcttct ctaccagccg tatgctgttt
     3421 ggtctggcgc aggaaggtgt ggcaccgaaa gcgttcgcta aactttctaa gcgcgcagta
     3481 ccagcgaaag ggctgacctt ctcctgcatc tgcctgctcg gtggcgtggt gatgctgtat
     3541 gtgaatccta gcgtgattgg cgcgttcacg atgattacaa ccgtttccgc gattctgttt
     3601 atgttcgtct ggacgattat cctttgctcg tacctggttt accgcaaaca gcgtcctcat
     3661 ctgcatgaga agtcgatcta caagatgccg ctcggcaagc tgatgtgctg ggtatgtatg
     3721 gcgttctttg tgttcgtggt cgtgttgctg acactggaag atgacactcg ccaggcgctg
     3781 ttggtcaccc cgctgtggtt tatcgcactg gggctgggct ggttgtttat tggtaagaag
     3841 cgggctgctg aactgcggaa ataaccgcat tatcatgctg gatggcgcaa tgccatccag
     3901 cttttagatt actcacccgc cagcgcgcgt gggaacagta cattgttttc cagactgatg
     3961 tgatccatca ggtcatcaat cagttcatta atgccgttat acatcgcttt ccaggtggtg
     4021 caggcttctg gcggcggtgt gacgttattg gtagtgtgtt tgatcacttc cagcagttcg
     4081 cccgcttcat cgtgctcgct ttccattacg ctgattggcc ccattgcctg gctgcccatg
     4141 ccttgtttga tcatcgggaa gaggatctgc tcttctttca tcatgtggct ggaaagctct
     4201 tcatgcagca tggtcaggta ttttgtcagc ccttttggca cgctcggttt gtcggcgtga
     4261 acgcgctcga ctttagtcgc ttgcaggatc agctccggca gttgctcgcg gtgacgatcg
     4321 tggtagcgca cgatgatatg gtcgatgatt tctgccagcg gggcgctacg ccagtctttc
     4381 tcaatcggtt gttcagcaag ctttgccagc tcagcttcaa tgacctcaac atccagttct
     4441 ttacgtgccg ccgcacgcgc cagcgtttgc ttaccgccgc agcagtaatc catatcatat
     4501 ttacgaaaca gagccgaagc gcgagggata gagagcgcca gttcacctaa aggttggtcg
     4561 cgataagcca tagctgatac ctcattctta ataagataag atgtatttta aatgcatctt
     4621 taaggcaaat gctataaccc ttacgtagca gaggcttatt taactcactg ccagtatgtc
     4681 aactttctga gacagattca gttaaaggct tttccggttt tgctctgact gcaatgacca
     4741 cgccaaccac taacagcgcg ataccgctca gcgtcatcag cggcggcatt tgctggcgta
     4801 tcaaaaaggt gtacagcaaa cctgccagtg tttcgaaaac gatcagcggc ccgagaatca
     4861 ctgtcggtaa tcgctggctg gcgacgttcc agcagagtgc gccaacccat gagcaaagca
     4921 cggctatcgc aaccatcaga ctaataaaca ccagcggacg ggggccaaaa ggtaaggaga
     4981 agtccggcgt ttgtatattc agccagtaac aggcgacgag atagccgatg agagaaaccg
     5041 gcagcgtgac cagcgcctgc gccgtcgccc acatcatcgg atgtttgtcg ggattttccc
     5101 gcagccagcg ggcgttgcgc agggcatacc atgcccagca gaccacggaa actaacgcta
     5161 gcacgatgcc agaggtataa cgtgcccagt caaaatcggg gagtccgtgg tttaactcag
     5221 caatattcac acacgccagg ccgatgccaa tacaaatcag tgccggggcg agttttcccc
     5281 acgcgagttt gccgtcgcgc tggctataaa gcagattggc aaagacagga atgaccaccg
     5341 gcagggtgcc aataatcatc gtagaaacag gcgcgccagt acgttgaatg gcactggcaa
     5401 ggcagaagta atagatgagg ttgcccatca tagtgagcat caaggcggta agccagtcgc
     5461 gacgcgccaa ctgacgcaga cgcacgcgtc ccagccaggc aatgggtagc gcaattaacc
     5521 ctaacgccag ataacgcccc atcgactgca acatcgccgg gtattccggc acgatcaacg
     5581 gcccgacaaa aataagcccc cacatcaacc ctgctaacag ggcgtacagc acgccgctaa
     5641 tcattactgg catccattgg tctgtcagaa gaaacgttca ggaagcagac atgattgctc
     5701 ccggcatccc gtcattatca gagaggatgc gggaggatgc cactttaatt aactagttat
     5761 taacattaaa aagatggctt acgctttcgg ctaacgttgt cgttgggcgg ccaatcaatt
     5821 tgctcagcgt tttgctgtca tcaaacagac cgcctttcga tgcgccaacg tcagaatccg
     5881 ccagcatatc cgccagtccg tcaggcaggc caacgctttt cagcgccgca gcgaaatcgg
     5941 tttcgctcag attttgatag gtaacctgtt tgccgctctg tttggtcagc tctgccgcta
     6001 actgtgtcaa cgtccaggca ctatcgcccg ccagctcgta aaccttgcct tcgtgaccgg
     6061 cttcgctaat cacgcgtgcc gcagctgccg cataatctgc ccgcgttgcc gaggcaattt
     6121 tgccatcgcc cgcggcaccg ataaatacgc cgtgctccag tgctgccggg gcgctggcga
     6181 gatagttttc ggtgtaccag ccgttgcgca gcagggtgta aacgatgcca gaatcagcca
     6241 acattttctc cgtctcgatg tgctcatcgg cgaggccgag cggagattta tccgcgtgaa
     6301 gcagactggt ataagcgata aatttcacgc cagccgtctt tgcggcatta ataacattac
     6361 gatgctgcgg ggcacgttga cccacttcgc tggaagagat cagcagtagt ttttccactc
     6421 cctgaagtgc agatgtcagt gcggcttcat cgccgtagtc agcctgacgc acggtaatgc
     6481 cttgtgctgt cagtgcctgg gcttttgccg gattacgaac gatagccact atttggctgg
     6541 caggaaccgt tttcatcaag gatttaataa catagtgacc aagttggcca gtggcaccag
     6601 taatagcgat catgggaagt ctccatcgtt ttgtcttgtg tttaaatacg ctaacaccta
     6661 aacttacttt tagtaagtac gtacaaaaag gtaagtatga aatgagtcag gttagcctgt
     6721 cacaacaact gaaagagggt aatctctttg cggaacagtg cccgtcgcgc gaggtgttga
     6781 aacacgtcac cagccgttgg ggggtgttga ttctggtggc gctacgcgaa ggtactcatc
     6841 gctttagcga cctgcggcgc aaaatcggtg gggtgagtga aaagatgctt gcgcagtcgt
     6901 tacaggcgtt agaacaggat ggttttctta accgtatcgc gtatccggtg gtgccgccgc
     6961 atgtggaata tagcctcacg ccgctgggcg agcaggtgag cgaaaaggtt gctgcactgg
     7021 cggactggat tgagttgaat ttgcccgagg tgttggcggt gcgggatgaa cgtgcggcat
     7081 aactgccggc tgcgcttatc cggcctacgg ttcatgactt gtagggcgga taagatgcgc
     7141 cagcatcgca tccgacaaaa gtgccggatg cggttgatga tttataggcc gaaaaagaag
     7201 tgtattactt actcaaatcc acctgataaa tcgcaaaccc gatatcatcg gtcgcgactt
     7261 tattcatcgg atattgccct ttctctttaa taaacgccgc ggctttatct gatggagagg
     7321 tttcgaaacg gatatccagt ttcttatcgc cagctatcgg tgctaaacgc cagttgttat
     7381 ctgccgccgg gtgaatttcc cccgcacgtt tcgactcatc agcaatccac gctgccagca
     7441 ccgagcggtt ctcatccggt gaagcaaaag cgatatggct gtcgcccgta ccggcaaatt
     7501 tgccgccgta agcgcgatag ttattggtgg caaccaggaa catggcgttc ggatcaatcg
     7561 gcttgccatt aaaggtcagg ttcttaatcc tttccgcatt ggcattaacc atctggcact
     7621 cgccgtcata acgggcaggc tgggtaacat caatctgata attcacacca tcaatcacat
     7681 caaagttata ggtgcggaaa ccatcccagt tgatgagtga ctgtggtttc gtgttgtcag
     7741 gatcaatctg gttaaactgt ccggcggagc actccagcca ctctttcacc tctttaccgc
     7801 tggctttcac cacaatcagc gtattggggt agagataaag atcggcggca ttacggaagg
     7861 tcaactggcc tttttccacc tccacatagc ttgccggatc atttttgcga ccaccaactt
     7921 taaacggtgc agcagctgaa agcaccggca gttttgccag atccggatcg ccctgaatgt
     7981 aatgctcgac atacgctttt tgcgcgttgt tcaccacctg cacggtcgga tcgtcctgca
     8041 ccagcgccag atagctatac atattgtcgg cggatttacc gattggcttg ctgacgaact
     8101 ggcgtgtggc atcgtgatcg gctttgagtg tttctaccag cttgctgtct tccgccgcga
     8161 gggattttat attggcgatg tcgtaaatcg gccgtgcttc cgctttcgcc tgcgtcacct
     8221 gccatttacc gctgttatta ctgagttgta agtcgaccac cccaagatga tcgccccaca
     8281 tgcccggcat taccgccgga acaccattca gcgtgccttt cgcgatatca gccccttcga
     8341 tatcagcaaa atctttacct gggaaaacgg cgtgagcatg gccaaacata atggcgttaa
     8401 cgccaggaat ttcactgagg taataaactg agttttccgc catcacttta tacggatcgg
     8461 cagatagccc ggaatgcgcc agaacgacaa cgacatcggc acctttctcg cgcatttcag
     8521 gcacgtattt gcgcacggtt tcggtaatat cattcaccgt cacttttccg gataaattag
     8581 ctttatccca gcccatgatt tgcggcggca cgacgccaat atagccaatc ttcagcgtct
     8641 gtttttttcc gtctttatcg accacttcgg tatctttaat taaatacggt gtaaacattg
     8701 gctgtttggt tctggcgtca atgacgttgg catttacata agggaatttc gctcccgcca
     8761 gcgcattttt caggtaatcc agaccgtagt taaattcatg attgccgagt gtaccgaccg
     8821 tgtaatccag cgtattcagc gccttataaa ccggatgaac atcacctgct tttaatcctt
     8881 tcgccgacat gtaatcggcc agtggactcc cctgaatcaa atcgccgtta tcgaccagta
     8941 cgctgttttt cacttcattg cgggcatcgt taatcaggct tgccgtacgt accagtccga
     9001 atttttccgt ggcggtgtct ttgtaataat cgaaatccat catgttgcta tgcagatcag
     9061 tggtttccat gatacgcaga tcgaccgtcg ctgcattcac actggcggca atcagcgtgg
     9121 ccaggagcgt tgcgctaaac ttaatcatca gggacatcct tttatcatcg ggaatacgaa
     9181 agaaaaggga gaataaacgt cttacttata gaacagtgaa gaatgccaca attttacgct
     9241 ttgaaaatga tgacactatc acagttggcg cattcattaa cgatagggta taagtaaaac
     9301 aataagttaa caccgctcac agagacgagg tggagaaatg ttagatcaag tatgccagct
     9361 tgcacggaat gcaggcgatg ccattatgca ggtctacgac gggacgaaac cgatggacgt
     9421 cgtcagcaaa gcggacaatt ctccggtaac ggcagcggat attgccgcac acaccgttat
     9481 catggacggt ttacgtacgc tgacaccgga tattccggtc ctttctgaag aagatcctcc
     9541 cggttgggaa gtccgtcagc actggcagcg ttactggctg gtagacccac tggatggtac
     9601 taaagagttt attaaacgta atggcgaatt caccgttaac attgcgctca ttgaccatgg
     9661 caaaccgatt ttaggcgtgg tgtatgcgcc ggtaatgaac gtaatgtaca gcgcggcaga
     9721 aggcaaagcg tggaaagaag agtgcggtgt gcgcaagcag attcaggtcc gcgatgcgcg
     9781 cccgccgctg gtggttatca gccgttccca tgcagatgcg gagctgaaag agtatctgca
     9841 acagcttggc gaacatcaga ccacgtccat cggctcttcg ctgaaattct gcctggtggc
     9901 ggaaggacag gcgcagctgt acccgcgctt cggaccaacg aatatttggg acaccgccgc
     9961 tggacatgct gtggctgcag ctgccggagc gcacgttcac gactggcagg gtaaaccgct
    10021 ggattacact ccgcgcgagt cgttcctgaa tccggggttc agagtgtcta tttactaaat
    10081 tcagatggca gaaacagagt atttcctgat tctgccatcc tgatttctcc caacctaaaa
    10141 agttataaat aaaaagagat tgtattttaa gtgcaaaaat tcaattgcta ataagttaca
    10201 ttttaataat gagcgttttt tgatggttta cttttataat gagatattta atggcgacat
    10261 aaaataacct aataaaataa ggttgtcata tgttacccag gatcagacac aataatttta
    10321 ttggtgcggt ggagctattt gtaaaatcat cgtatacaaa aacacattca aacaattttt
    10381 taataatatt caacatgcat ttaggaaaaa agattgggtt tcgaattatg atagcctgtt
    10441 aactttgcgg gagttctttc gttgcgcaac tcagattgat aaagatagtt atcaagtgct
    10501 ttcatcaaaa aatgaaactg ttaacgccat ggataagttt cttatcagtt tcagccttaa
    10561 agataacggt gccgaatata caatgacatt gcgaggcagt ggatttgaat acgaagaaat
    10621 ccccataaca ataaatgagt ataactcatt catggatttc aaaaaccgtg aatttccgtt
    10681 agaacaaaac agacgattgt atgcctggga tattctgcag aaaaaacagt ctgacatacc
    10741 gaaaaggatt aaaggttata ttcaccaggc gattggtgac gtgtctttag gttatgcctt
    10801 attggaggat atagtaagca aattaaaacg gggtaaattt gaactccaaa taccaggcgg
    10861 tggaattaaa gaatgtgatg gatggtatat ttacgaaaaa ataattgatg ataattttgc
    10921 catagtcata gaatctttgg gctttgcgct taaaatctat ggaggggatg aacgttttcg
    10981 taatggttcc tctgttgttt tggaggatga agattactct cttatttata attttctggt
    11041 taatgcaggt tgccaacaag tggaattagc cgaacaagtg gatgcgatag taagtgcgaa
    11101 tctggccgca gatagtaata ttaccaaaga aaagatttgc gagaaatata aatctaccat
    11161 tgaggcgttt aaaaaagagc aactagcgtt accagtatta gttcggcgta agaactcata
    11221 cacttaattc ccctatccca taggtatcga caggggaata ttatttttgc agactctatg
    11281 ttgttgccat tatttgagca acttttgcag caggtccatc acttgctgca cctcttcctg
    11341 agtgagcgcc ccgtctttgg cccattgcac gcgaccatcc ttatccagca ccactacagc
    11401 ggaactttct tcatccagct gccaggcacc gcgcgcgacg ccattgctat cgacaataaa
    11461 ctgcgaccag ggataaagct ttttattact ctccagactg ctgcgcacaa acatgccgga
    11521 acccggaatt gcgtcgtcgg tgttaacaat ggtggtggtc tggtaacgat cgtgcggtaa
    11581 cttcgctgat ttaatcgctt caatcagcgt cgcgtttttc tcttgtgcag aggtgcgacc
    11641 agcaatatgt tgcagtactc gcacttttcc cactaactgc gcgctgttcc aggttttgta
    11701 gctaaactga tctttatcaa gcaccaactc gccccgatcg gtaatgccaa tcggcggcac
    11761 tcgctgaccg gtttcgaact gatgtgcgga agccatcatc ggcaacagca ggcaggtgag
    11821 taccagaatc ttgcgtaggg tcatggtgtt tccttcttat gatatgcagg tgatccgacc
    11881 acttgggtct gagttttaat catatgtgct atttatcgaa tttcccgcaa gtgtgatgcc
    11941 agtttgcggt caagcgcaca aatcatatga aaaatgaatg cttatactga agaccgcgct
    12001 tcggtaaaaa gataattctg aataattgta acctttaggt aaaaaaagtt atacgcggtg
    12061 gaaacattgc ccggatagtc tatagtcact aagcattaaa atttgcgcct cataatagtt
    12121 gggccgattg tggcaccgca caggcgtaat actcagcagg agataacaat gaaaattttc
    12181 caacggtaca acccacttca ggtggcgaag tacgtaaaga tcctgttccg tggacggtta
    12241 tacatcaagg acgttggcgc ttttgaattt gataagggta agattcttat cccaaaagtg
    12301 aaggataagc tgcatttgtc agtgatgtcc gaagttaacc gtcaggttat gcgtctgcaa
    12361 acagagatgg cttaaccaaa gtgctatgca gtaataagac ggctcctgat tcaggagccg
    12421 ttgatgtttc tgggggttac gcgacgcttt cttctttatc tttagcgtca ggcagttttg
    12481 gcgaaagggc ggtggccttg ctgtcgatcc gggtcaccag cagctggtcg atgcggtagt
    12541 tatcgatatc caccacttca aatttgtagc cggcgaattt caccgaatcg gtgcgtttcg
    12601 ggatcttacg cagcataaac atcataaagc cgccgatggt ttcgtagttg cccgactgcg
    12661 ggaactcgtc aatatccagc acgcgcatga cgtcgtcaat cggagtgccg ccgtcaatca
    12721 gccatgagtt ctcatcacgg gcgacaatct gctcttccag accctgaccg accagatcgc
    12781 ccatcagcgt ggtcatcacg tcgttgaggg tgatgatccc caccaccagc gcgtactcgt
    12841 tcatgatcac cgcgaagtct tcacctgcgg ttttaaaact ttccaacgcc tctgaaaggg
    12901 ttaacgtatc cggcacaatc agcgtgttgc gaatttgtac gccgctgttc agtgccaggc
    12961 tttggttagc cagcacgcgg ttcagcaggt ctttagaatc gacatagccg atgatgtggt
    13021 caatatcttc attacagacg aggaacttag agtgcggatg ttccgccacc ttattcttca
    13081 ggctttgctc atcttcgtgg agatcaaacc aaatcacgtt ttcacgcggt gtcattgacg
    13141 acggaacggt acgggattcc agctcaaaga cgttttcaat cagctcgtgt tcctgtttac
    13201 gtaacacgcc cgccagcgca ccggcttcca ctaccgcgta gatgtcatca gaagtgatgt
    13261 catctttacg taccattggc agtttgaaaa tacggaagat tatgttcgcc agtccgttga
    13321 agaaccacac cagcggggtg caaacgtaca ggcagaagcg catcgggttg atgatacgca
    13381 aagccacagc ttctggcgca atcataccga tgcgtttcgg ggttaaatcc gcaaacagga
    13441 taaacatgcc agtcactaac gagaaagaga gaataaagct cagttgctca gagagctctg
    13501 ccgacatata gcgggagaac aggctgtgaa aagctggaga aaatgccgca tcaccgacga
    13561 taccgccgag aatcgccact gcgttcagac cgatttggac cacggtaaag aacatgccgg
    13621 gattttcctg catattcaga acgcgttggg catttatatt gccttcatca gccagcagtt
    13681 taagtttgat tttgcgtgag gcggcaagcg agatctcgga catcgagaag aacgcactta
    13741 cagcgatcaa gcagagtatg actaaaatac tgtttaacat atcttatccg acctttcagg
    13801 ccagatcctc ggaaggggaa gttgattaat ttgtgtgaaa tacacattga aagccgattc
    13861 gaagaaagtg aaccggcatt ttcagtggct agtatagcgt aaggtactgt aaagtcgcca
    13921 gagggttaaa attcagactg ctgataaatg caatactgcc tgatgcgcta tgccgatcag
    13981 gcctacgcag tccttgcaat atattgaatt tggacgattt tgtaggcctg gtaaggcgtt
    14041 tacgccgcat ccggcataaa taaagcgtac tttatcaaca atctacattt gtacccgtaa
    14101 cgctatgctt ccggcggcag acagacgcca attccgccaa ttccacagta accatacggg
    14161 tttttatgca gatattgctg gtggtcatct tcggcataat aaaacggtgt ggcgttagcg
    14221 atttccgtgg tgatgcgacg atcgtcatcg gcggcaagca tcgccgcctg aaaacgttcc
    14281 agactggcgc gagctgcggc atcctgttct ggggtcagcg gataaatcgc tgaacgatac
    14341 tgcgtgccgt ggtcattgcc ctgacgcatt ccctgggcgg gatcgtgatt ctcccaaaat
    14401 acctgtagca actgctcata gctgatgacg gaaggatcgt aaacaatgcg taccgcttcg
    14461 gcatgacccg tatcaccgga gcacacttcc cgataagtcg gatttggcgt atagccgccg
    14521 gtatagcctg cggcggtgct gtaaacgccg ggtaactgcc agaacagacg ctccacaccc
    14581 cagaaacaac ccatcgcaaa aatggcaatc tccattccgt caggtacatt ggtcattgag
    14641 tgaccgttga ccgcatgcag cgtggctacg ggcatcgggg tgttacgtcc aggcagggca
    14701 tcggcggggg aaaccagatg ctttttatca aataaactca tggtgtcgct ctcccgaaaa
    14761 tcggtcattg gggttaaggt tgtaacaaga ggcgtatttg cacacaataa ccaccgtgaa
    14821 taggtctaaa gtaaaacata agaaatattt ggggtttagt ctgcttttta atccatatta
    14881 ctggattttt gttaagccgt ttaacggcgt tccaggggca ggaaaaaagg atattcagga
    14941 gaaaatgtgc gctatatccg acagttatgc tgtgtaagct tactctgctt aagcggatct
    15001 gccgtcgccg cgaacgtccg tctacaggtc gaggggttat cgggacagct ggaaaagaac
    15061 gttcgtgcgc agctttctac gattgaaagt gatgaagtga cgccagaccg tcgctttcgc
    15121 gcacgcgtcg atgatgccat ccgcgaaggt ctgaaagcgc tgggttatta ccagccgacc
    15181 attgaatttg atctccgtcc accgccaaag aaagggcggc aggtattgat cgccaaagtc
    15241 acgccaggcg tgccggtgtt aattggcggc accgatgtgg tattgcgcgg cggcgcgcgg
    15301 accgataaag actatttgaa attgctcgat actcgcccgg ctattggcac ggtgctgaac
    15361 cagggcgatt atgaaaattt caaaaagtcc ttaaccagca ttgcgttgcg taaaggttat
    15421 ttcgatagcg aatttaccaa agcgcagctg ggcattgcgc tcggcctgca taaagccttc
    15481 tgggatattg attataacag tggcgaacgt taccgctttg ggcatgtgac ctttgaagga
    15541 tcacaaatcc gcgatgaata cctgcaaaat ctggtgccgt ttaaagaggg cgatgagtac
    15601 gaatcgaaag atctggcgga actgaaccgc cgactttctg ctaccggctg gtttaactcg
    15661 gtggtggtgg ctccacaatt tgataaagcg cgcgaaacga aagtattacc attgacgggc
    15721 gtggtttcgc cgcgaacaga aaacaccatc gaaaccgggg tcggttactc tacggacgtg
    15781 ggaccgcgcg tgaaagcgac gtggaaaaaa ccgtggatga actcatacgg tcacagtctg
    15841 accaccagta ccagtatttc cgcgccggaa cagatcctcg acttcagcta taaaatgccg
    15901 ctgctgaaga atccactgga acaatattat ttggtgcagg gcggttttaa gcgcactgac
    15961 ctgaacgata ccgaatctga ctccactacg ctggtggctt ctcgctactg ggatctctcc
    16021 agcggctggc agcgtgccat taacctgcgc tggagtctcg accactttac ccagggtgaa
    16081 attaccaaca ccacgatgct gttttatcct ggggtgatga ttagccgcac gcgttctcgt
    16141 ggtggcctga tgccaacctg gggcgactcg caacgctact ctatcgacta ctccaacact
    16201 gcctggggct cagatgtcga tttctccgtt ttccaggcac aaaacgtctg gatccgcaca
    16261 ctgtacgatc gccatcgttt tgtgacacgc ggcacgctgg gctggattga aaccggtgat
    16321 ttcgacaaag taccgccgga tctgcgtttt ttcgccgggg gcgaccgcag tattcgtggc
    16381 tacaaataca aatctatcgc tccgaaatac gccaacggtg acctgaaagg ggcctcgaag
    16441 ttgataaccg gatcgctgga gtaccagtac aacgtgaccg gaaaatggtg gggcgcggtg
    16501 tttgtcgata gtggcgaagc ggtaagcgat attcgccgca gcgactttaa aaccggtacc
    16561 ggggtcggcg tacgctggga atcgccggtc gggccaatca aactcgattt tgccgtaccg
    16621 gtcgcggata aagacgaaca cgggttacag ttttacatcg gtctggggcc agaattatga
    16681 gtttatggaa aaaaatcagc ctcggcgtgg ttatcgttat cttactgttg ctgggatcgg
    16741 tggcgtttct ggtgggcacc accagcggcc tgcatctggt atttaaagcg gcggatcgct
    16801 gggtgccagg actggatgtt ggcaaggtca ccggcggctg gcgcgatctc accttgtctg
    16861 acgttcgtta tgagcagcca ggcgtggcgg taaaagcagg caatctgcat ctggcggtcg
    16921 ggcttgagtg cctgtggaac agcagtgttt gtattaatga tctggcgctg aaagacatcc
    16981 aggtcaatat cgacagcaaa aaaatgcccc cttctgaaca ggttgaagaa gaggaagata
    17041 gcggtccgct ggatctctcc acgccgtatc ccatcaccct aacacgggtg gcactggaca
    17101 acgtcaacat caagattgat gacaccacgg tatcggtgat ggacttcacc tccggcctga
    17161 actggcagga gaaaaccctg accctgaaac cgacgtcgct gaaaggcctg ctgattgctc
    17221 tgccgaaagt ggcggaagtg gcgcaggaag aagtggtcga accgaaaatt gaaaatccgc
    17281 agccggagga aaagccgctc ggcgaaacgc tgaaagatct cttttctcgc ccggtattgc
    17341 cggaaatgac cgacgtgcat ttgccgctta acctgaacat tgaagagttt aagggcgagc
    17401 agttgcgcgt gacgggcgac acggacatca ctgtgagcac catgctgctg aaagtgagca
    17461 gcattgacgg caatactaaa ctggacgccc tggatatcga ttccagtcaa gggatcgtca
    17521 acgccagcgg cacggcgcag ctgtcagaca actggccggt ggacatcact ctcaatagta
    17581 cactgaacgt ggagccgttg aaaggtgaaa aggtgaagct gaaagtgggc ggcgcgctgc
    17641 gcgaacagct ggagattggc gttaatcttt ccggtccggt ggatatggat ttacgcgccc
    17701 agacgcgact ggcggaagcc ggattgccgc tcaacgtgga agtgaacagc aaacagattt
    17761 actggccgtt cactggtgag aagcagtatc aggcggatga tctgaaactg aaacttaccg
    17821 gcaaaatgac cgattacacg ctctctatgc gtacggcagt gaagggactg gagatcccgc
    17881 cagccaccat tacccttgat gccaaaggta atgaacagca ggtcaatctc gacaaactca
    17941 ccgtcgcggc gctggaaggg aaaactgaac tcaaggcgtt gctcgactgg cagcaggcca
    18001 ttagttggcg cggtgagcta acgcttaacg gcattaacac cgccaaagag atcccagagt
    18061 ggccgtcgaa actcaatggc ttgattaaaa cccgcggtag cctgtacggc ggcacctggc
    18121 agatggaggt gccagaactg aagctgaccg gtaacgtcaa acagaacaaa gtgaacgttg
    18181 acggcacgct gaaaggcaac agttatatgc agtggatgat cccagggctt catctggaac
    18241 tggggccaaa cagtgccgaa gtgaaaggcg agctgggggt aaaagatctc aatcttgatg
    18301 ccaccatcaa cgcgccgggg ctggataacg cgctgccggg gcttggcggt acagcgaaag
    18361 ggctggtgaa agtacgcggc acggtggaag cgccacaact actggcagat atcaccgcgc
    18421 gcggcctgcg ctggcaggaa ctttccgtgg cgcaggttcg cgtggaaggc gacattaaat
    18481 ccaccgatca gatcgccggg aaactcgacg tacgcgttga gcaaatttcg cagccggatg
    18541 taaatatcaa cctcgtcacc ctgaatgcca aaggcagcga aaaacagcac gagttacagt
    18601 tgcggattca gggcgagcct gtctccgggc agcttaatct ggcaggaagt tttgatcgca
    18661 aagaagaacg ctggaaggga actcttagca atacccgctt ccagacgccg gtcggcccgt
    18721 ggtcgctgac ccgcgatatt gcgctggatt accgcaataa ggagcaaaaa atcagcatcg
    18781 ggccacactg ctggcttaac ccgaatgcgg aactgtgcgt gccgcaaact atcgatgcgg
    18841 gtgccgaagg gcgtgcggtg gtgaatctca accgcttcga cctggccatg ctgaaaccat
    18901 ttatgccaga aaccactcag gccagcggta tcttcacggg taaagcggac gttgcctggg
    18961 acaccaccaa agaggggctg ccgcagggca gtatcaccct ttcggggcgt aacgtgcagg
    19021 taacgcaaac cgtcaacgat gcggcgctgc ccgtggcgtt tcagacactg aatctgacgg
    19081 cggaattgcg taacaaccgt gccgaattgg gctggaccat ccgcctgacc aataacggcc
    19141 agtttgatgg acaggtgcag gtgaccgatc cgcaaggccg ccgtaatctt ggtggcaacg
    19201 tcaatatccg taacttcaac cttgcgatga taaaccccat ctttacccgt ggggaaaaag
    19261 cagcggggat ggtgagtgcc aacttgcgtc tgggtggtga tgtgcaaagc ccgcagttgt
    19321 ttggtcagct tcaggttacg ggtgtggata tcgacggcaa ctttatgccg tttgatatgc
    19381 aaccgagcca gcttgcggtc aactttaatg gtatgcgctc gacgcttgcc ggtacagtac
    19441 ggacccagca gggtgaaatc tacctgaacg gtgatgccga ctggagccaa attgaaaact
    19501 ggcgggcgcg ggtaacggcg aaaggcagta aagtgcggat caccgtgccg ccgatggtac
    19561 gaatggatgt atcgccagat gttgtcttcg aggctacacc aaacctgttt accctcgatg
    19621 gtcgcgtgga tgtcccgtgg gcgcgcatcg tggtgcacga tctgccggaa agcgcagtag
    19681 gcgtctccag cgatgtggtg atgcttaacg ataacctgca accggaagag ccgaaaacgg
    19741 cgtcgattcc gattaacagt aacctgattg tccacgttgg caacaatgtg cgcattgacg
    19801 cctttggcct gaaagcgcgg ctgacgggcg atcttaacgt cgttcaggac aaacaagggc
    19861 tgggcctgaa cgggcagatc aacatccctg aagggcgctt ccatgcctat ggtcaggatc
    19921 tgattgtgcg taaaggtgag ttactgttct ctggtccgcc ggatcaaccg tatcttaata
    19981 ttgaagctat tcgtaacccg gatgctacag aagacgacgt aatcgccgga gttcgcgtca
    20041 ctggtctggc ggacgaaccg aaagcggaga tcttctctga cccggcgatg tcgcaacaag
    20101 ctgcattgtc ttatttgcta cgtggacaag ggctggagag cgatcagagc gacagtgcgg
    20161 caatgacctc gatgctgatt ggtctggggg ttgcgcaaag tggccagatt gtgggtaaaa
    20221 tcggcgagac gtttggcgta agcaatttag cgctcgacac ccagggagta ggcgactcct
    20281 cccaggtagt ggtcagcggc tatgtattgc caggtctgca agtgaaatac ggcgtgggta
    20341 tatttgactc tatagcaaca ctcacgttac gttatcgcct gatgcctaag ctatatctgg
    20401 aagccgtgtc tggtgtagac caggcactgg atttgctcta tcagttcgag ttttagcaat
    20461 gcgaatattt gtctacggca gtttacgcca caaacaaggc aacagtcact ggatgaccaa
    20521 tgcccagtta ctgggcgatt tcagtatcga taactaccag ttgtatagcc tgggccacta
    20581 tccaggcgca gttccgggga acggaacagt acacggtgaa gtttatcgta ttgacaacgc
    20641 cacgctggcc gaacttgatg ccttgcgcac caggggcggt gaatacgcgc gccagttgat
    20701 tcagacgccg tacgggagtg catggatgta cgtttatcaa cgacccgtcg atggattaaa
    20761 gctaattgaa agcggcgact ggttagacag ggataagtaa taataaaagc acgccacctt
    20821 cgggtggcgt tgttttttgc gagacgactc gcattctgtt ttgtaattcc ctcacctttt
    20881 gcttttctct ccgagccgct ttccatatct attaacgcat aaaaaactct gctggcgttc
    20941 acaaatgcgc aggggtaaaa cgttgcctgt agcaccgtga gttatacttt gtataactta
    21001 aggaggtgca gatgcgtatt accataaaaa gatgggggaa cagtgcaggt atggtcattc
    21061 ccaatatcgt aatgaaagaa cttaacttac agccggggca gagcgtggaa gcgcaggtga
    21121 gcaacaacca actgattctg acacccatct ccaggcgcta ctcgcttgat gaactgctgg
    21181 cacagtgtga catgaacgcc gcggaactta gcgagcagga tgtctggggt aaatccaccc
    21241 ctgcgggtga cgaaatatgg taaagaaaag tgaatttgaa cggggagaca ttgtgctggt
    21301 tggctttgat ccagcaagcg gccatgaaca gcaaggtgct ggtcgacctg cgcttgtgct
    21361 ctccgttcaa gcctttaatc aactgggaat gacgctggtg gcccccatta cgcagggtgg
    21421 aaattttgcc cgttatgccg gatttagcgt tcctttacat tgcgaagaag gcgatgtgca
    21481 cggcgtggtg ctggttaatc aggtgcggat gatggatcta cgcgcccggc tggcaaagcg
    21541 tattggtctg gctgcggatg aggtggtgga agaggcgtta ttacgcttgc aggcggtggt
    21601 ggaataaggt gtgtttattt atcgcgggca taaaaaaacc cttactaacc gaagcccggt
    21661 gttcagggtt attgcgctat aagaacttat ttattctttg cgcgctcgaa ggaggcaacg
    21721 atttcagctt tagcggcttc tgcgttttcc caaccttcaa ctttcaccca cttgcctttt
    21781 tcgaggtctt tgtagtgctc gaagaagtga gcgatctgcg ctttcagcag ctctggcaga
    21841 tcgttaacgt ctttaatgtg atcgtattct ttgctcagct tggtgtgcgg aacagcaatc
    21901 agtttcgcat cttcaccggc ttcgtcggtc attttcagaa cgccaaccgg acggcaacgg
    21961 atcacagaac ccggctgcag cgggtacgga gtcgggacca gtacgtcaac cgggtcaccg
    22021 tccagagaca gggtgtggtt gatgtaaccg tagttgcacg gatagaacat cgcggtggac
    22081 atgaagcggt caacgaacag tgcgccgctc tctttgtcga tttcgtattt gatcggatct
    22141 gcgttagccg ggatctcaat aacaacgtag atgtcttccg gcagatcttt acccgcaggg
    22201 acgttgagta agctcatgtc tgtttccttt aaaaatatgt ggcaaacaag tgccgagtat
    22261 tatagccaac tcgcgccgaa tgtcttcgct tgttttcgtc ttcattttcc tttttcacca
    22321 gttttaagac ggtatacaga gcaggaaaat ccataaccgt agccgcattt ttcatagtga
    22381 gatgaaagcg attacaaact tgtgattaac gttttattta cttttttgaa gtgtgatgta
    22441 acgcaatccg ttacataacg aattgtctat agttttttcg cgaacatctt ttcaccaata
    22501 ataattaccc cgacgaggac aaccctatgt ggaaacgctt acttgtagtc tctgcagtct
    22561 cggcagccat gtcgtctatg gcgttggccg ctccattaac cgtaggattt tcgcaggtcg
    22621 gatcggaatc tggctggcgc gccgcagaaa ccaatgtggc gaaaagtgag gccgaaaaac
    22681 gcggaattac gctgaaaatt gccgatggtc agcaaaagca ggaaaaccag attaaagcgg
    22741 tacgttcctt cgtcgcgcaa ggggtggatg cgatctttat cgctccggtg gttgcgactg
    22801 gttgggaacc ggtattaaaa gaggcgaaag atgccgaaat cccggtcttc ttgctcgatc
    22861 gttctattga tgtgaaagac aaatctctct atatgaccac cgtcactgcc gacaacattc
    22921 tcgaaggcaa gttgattggt gactggctgg taaaagaagt gaatggcaaa ccatgcaacg
    22981 tggtggagct gcagggcact gttggggcca gcgtcgccat tgaccgtaag aaaggctttg
    23041 ccgaagccat taagaatgcg ccaaatatca aaattatccg ctcgcagtca ggtgacttca
    23101 cccgcagtaa aggcaaagaa gtcatggaga gctttatcaa agcggaaaac aacggcaaaa
    23161 acatctgcat ggtttacgcc cataacgacg acatggtgat tggtgcaatt caggcaatta
    23221 aagaagcggg cctgaaacca ggcaaagata ttctgacagg ttctatcgac ggcgtaccgg
    23281 atatctacaa agcgatgatt gatggcgaag cgaacgccag tgttgaactg acgccgaaca
    23341 tggcaggccc tgctttcgac gcgctggaga aatacaaaaa agacggcacc atgcctgaaa
    23401 agctaacgct gaccaaatct accctttatc tgcctgatac cgcaaaagaa gagttagaga
    23461 agaagaaaaa tatggggtat tgagggttgc tatgcctgat gccgattcgt aggccggatg
    23521 aggcgctcgc gccgcatccg gcgatggtgc actgaagcct gatgcgacgc ttaccgcgtc
    23581 ttatcatgcc tactgggagc acgctttaca ccgggggaaa ccatgacgac cgaccaacac
    23641 caggaaatcc tccgcaccga aggattaagc aaatttttcc ccggcgttaa agcgttagac
    23701 aacgttgatt tcagcctgcg ccgtggtgaa atcatggcgc tgctcggtga aaacggggcg
    23761 ggaaaatcga cgctaatcaa agcattaacc ggtgtttacc acgccgatcg cggcaccatc
    23821 tggctggaag accaggctat ctcaccgaaa aataccgccc atgcacaaca actcggcatc
    23881 ggaaccgttt atcaggaagt caacctgcta cccaatatgt cggtcgctga taatctattc
    23941 ataggtcgcg aacccaaacg tttcgggctt ctacgccgta aagagatgga aaagcgcgcc
    24001 accgaactga tggcatctta cggtttctcc ctcgacgtgc gcgaaccgct caaccgcttt
    24061 tcagtcgcga tgcagcaaat cgtcgccatt tgccgggcta tcgatctctc tgccaaagtg
    24121 ctgatcctcg atgaacccac cgccagtctc gacacccagg aagtggagtt actgtttggc
    24181 ctgatgcgtc agttgcgtga tcgcggcgtc agcctgatct ttgtcactca ctttatcgat
    24241 caggtctatc aggtcagcga tcggatcacc gtcttacgca acggcagttt cgtaggttgt
    24301 cgggaaacgc gcgagctacc gcagatcgaa ctggtaaaaa tgatgctggg gcgcgagctg
    24361 gatacccacg cgctacagcg tgccgggcga acattgttga gcgacaaacc cgttgccgcg
    24421 ttcaaaaatt acggcaaaaa aggaacgata gcaccgtttg atctcgaagt gcgccccggc
    24481 gagatcgtcg gcctggcagg cttgctggga tcaggacgta ccgaaaccgc cgaagtgatc
    24541 ttcggtatca aacctgctga cagcggcacg gtgttgatca aaggcaaacc gcaaaccctg
    24601 cgatcgccac atcaggcttc ggtactgggt atcggcttct gcccggaaga caggaaaacc
    24661 gatggcatca tcgctgccgc ctcggtgcgg gaaaatatca tcctcgctct ccaggcccag
    24721 cgcggctggc tacgacccat ttcccgcaaa gagcagcaag agattgccga acgctttatc
    24781 cgccagcttg gcattcgcac accttcaact gaacaaccga ttgagtttct ctctggcggc
    24841 aatcagcaaa aagtgttgct ttcacgttgg ctactgaccc gaccgcaatt tctgatcctt
    24901 gatgagccaa cccgcggcat tgatgttggt gcccacgccg agatcatccg cctgattgaa
    24961 acgctatgcg ccgatggtct ggcgctgctg gtgatctcct ctgaactgga agagctggtg
    25021 ggctatgccg accgggtgat catcatgcgc gatcgcaaac aggtggcgga gatcccgctg
    25081 gcagagcttt ccgttccggc gatcatgaac gccattgcgg cgtaaggaga acagtgtgat
    25141 gcctcaatct cttccggaca ccactacgcc aaaaaggcgc tttcgctggc cgacggggat
    25201 gccgcagctg gtagcactat tgctggtgct gctggtcgac agcctggtag ccccgcattt
    25261 ctggcaggta gtgcttcagg atgggcgttt gttcggtagc cctatcgaca ttcttaaccg
    25321 tgcggccccc gttgcgctgt tggctatcgg aatgacgctg gtgatcgcaa caggtgggat
    25381 tgatctctcc gtgggggcgg tgatggctat cgccggagcc acaacggctg cgatgacggt
    25441 cgcgggattc agcctgccga ttgttttgtt aagcgccctg ggcactggca tcctggcggg
    25501 attgtggaac ggcatactgg tagcgatcct caaaattcag ccgtttgttg ccaccctgat
    25561 cctgatggtc gccgggcgcg gcgtggcgca actgatcacc tccggacaga tcgtcacgtt
    25621 taactcgccg gatctctcat ggtttggcag tggatcgctg ttgttcctgc caacgccggt
    25681 cattatcgcg gtgctgacgc ttatcctgtt ctggctgttg acccgcaaaa cggcgctggg
    25741 gatgtttatc gaagccgttg gtatcaacat tcgggcggca aaaaatgccg gggtaaacac
    25801 gcggatcatc gtcatgctta cctacgtgtt gagcgggctg tgtgcggcga ttgcgggcat
    25861 tatcgtggcg gcggatattc gcggtgccga tgccaataac gccgggttat ggctggagct
    25921 ggacgccatt ctcgcggtgg ttattggcgg cggatcgctg atgggcggac gttttaacct
    25981 actgctttcg gtggtggggg cgctgattat tcaggggatg aacaccggaa ttttgctttc
    26041 gggctttccg ccagagatga accaggttgt aaaagcggtg gtggttcttt gcgtgctgat
    26101 tgtccagtcg caacgcttta tcagtctgat taaaggagta cgtagccgtg ataaaacgta
    26161 atttgccact gatgatcacc atcggcgtct ttgtgttggg ttatctttac tgcctgaccc
    26221 agtttcccgg ttttgcttcc acaagagtga tctgcaatat cctgaccgat aacgcctttc
    26281 ttgggatcat tgccgttggc atgacctttg tgatcctctc cggtgggatc gatctctccg
    26341 tcggttcggt gatcgccttt actggcgtgt ttctggcaaa agtgattggc gatttcggcc
    26401 tctcgccgct gctggcgttt ccgctagtgc tggtgatggg ctgtgccttc ggcgcattta
    26461 tggggctttt gatcgacgcc ctgaagatcc cggcatttat cattaccctg gcggggatgt
    26521 tctttttgcg cggtgtcagc tatctcatct cagaagagtc gatcccgata aaccatcctg
    26581 tttatgacac gctttcaagc cttgcatgga aaatccccgg cggcggtcgc ttaagtgcga
    26641 tggggctgct gatgctggcg gtggtggtta tcggtatttt cctcgcgcat cgcacccgct
    26701 ttggtaatca ggtatacgcc attggcggca acgcaacgtc ggcgaacctg atggggattt
    26761 ccactcgcag caccactatt cgcatttata tgctctccac cggactggca acgctggcgg
    26821 gtattgtctt ctcgatttat acccaggccg gatatgcgct ggcgggcgta ggtgtggaac
    26881 tggatgctat cgcctcagtg gtaattggcg gtacgcttct gagcggtggc gttggaacgg
    26941 tattagggac gctttttggc gtggcgattc agggactgat tcagacttac ataaactttg
    27001 atggcacgct gagctcatgg tggacgaaaa tcgccatcgg tattttgttg tttattttta
    27061 tagcattaca gcgtggatta acggtgctgt gggagaatcg tcagagttcg ccagtgacaa
    27121 gagtcaacat tgcgcagcga taaaaacgcc tctccgtgtg gagaggcgca ggagattacg
    27181 cgtccgggaa ctcacggata aagcgttcga catcttcaac catatggtcg ttgccgacaa
    27241 agaacgaacg gcgctggtgc agagtttccg ggatgatatc cagaatacgc tctttgccat
    27301 cgctcgcttt accgcccgct tgttccgcca ggaatgccat cgggttgcac tcataaagca
    27361 aacgcagttt gccgtccggg tggctggcgg tgcttgggta gagataaata ccgcctttca
    27421 gcaggttacg gtggaaatcc gcgaccagtg aaccgatata acgtgaggta tacgggcggt
    27481 tggtggattt atcttcttcc tggcagaatt taatgtactt cttcaccccg ttcggaaact
    27541 taatgtagtt tccttcgttg atggagtagg ttttgccttt ctccgggaag cgcatccgtt
    27601 cctggcacag gcagaaaacg ccgagcgaag gatcgtaagt aaaggcgtga acaccgcatc
    27661 cggtggtgta aaccagcatg gtagaggagc cgtataccac gtaacctgcc gcaacctgtt
    27721 tgttaccagg ctggaggaaa tcttcttccg ttaccggcgt gccgacgggc gtaacgcggc
    27781 ggtagatgga gaaaatggta ccgacagaga cgttaacatc gatgttggac gagccatcca
    27841 gtgggtccat cagcaccacg tattttgcat gttcacagcc ttcaaagacg acaatctcat
    27901 cttcttcttc agaggcaatg cccgcaacga tatcgcgtgc tttcagtgcg gctttcagtt
    27961 tttcattagc gaacaagtcg agtttttgct gaacctcgcc ctgcacgttc tcagcaccgc
    28021 tggcacccag gatatcaacc agtcctgctt tgttgatatc gcgatggata atcttggcgc
    28081 ccagttttat tgccgacagc aaagcagtga gctcaccggt agcatgagaa aactcgtgct
    28141 gcttttcgac aataaattca cctaacgttt tcataaaact ttccctgcaa tgtttatgga
    28201 gtaaagcgac cgtaacaatc ttaacaaata atcggaatgt tgcgctcagg tgaatcgcgc
    28261 cagcaaattg cggattatcc tgaaatgcgt ttctcacttg cccgacatat gcgtaaaatg
    28321 agcggcagat taaaaaagga tagtgacgta tgcgcattca tattttagga atttgtggca
    28381 cgtttatggg cggtctggcg atgctggcgc gccagttagg ccatgaagta acgggttcgg
    28441 acgccaatgt gtatccgccg atgagcacct tacttgagaa gcaaggcatt gaactgattc
    28501 agggttacga tgccagccag ctcgatccgc agccggatct ggtgattatt ggcaacgcca
    28561 tgacccgtgg aaatccgtgt gtggaagcgg tactggaaaa aaacatccct tatatgtcag
    28621 gtccacagtg gctgcacgat tttgtgctgc gcgaccgctg ggtgctggcc gttgccggta
    28681 cacatggcaa aaccaccacc gcgggaatgg cgacctggat tctggaacag tgcggttaca
    28741 aaccgggatt tgtgatcggc ggtgtgccgg ggaactttga ggtttcggcg cgtctgggcg
    28801 aaagcaactt ctttgttatc gaagcggatg agtatgactg cgccttcttc gacaaacgct
    28861 ctaaatttgt tcattactgc ccgcgtacgc tgattctcaa caaccttgag ttcgatcacg
    28921 ccgatatctt tgacgacctg aaagcgatcc agaaacagtt ccaccatctg gtgcgtatcg
    28981 ttccggggca gggccgtatt atctggccag aaaacgacat caacctgaaa cagaccatgg
    29041 cgatgggctg ctggagcgag caggagctgg tgggcgagca aggtcactgg caggcgaaaa
    29101 agctgaccac cgatgcttcc gaatgggaag tcttgctgga tggcgaaaaa gtgggcgaag
    29161 tgaaatggtc gctggtaggc gaacataata tgcacaatgg cctgatggcg attgcggcgg
    29221 ctcgccatgt tggtatagcg ccggcagatg ccgctaacgc gctgggttcg tttattaacg
    29281 ctcgccgccg tctggagttg cgtggtgaag cgaatggcgt aacggtatat gacgattttg
    29341 cccatcaccc gacggcgatt ctggcaacgc ttgcggcgct gcgtggcaaa gttggcggta
    29401 cggcgcgcat tattgctgtg ctggaaccgc gctcgaatac catgaaaatg gggatctgca
    29461 aagacgatct ggcaccttca ttaggtcgtg ccgatgaagt cttcctgctg caaccagcgc
    29521 atattccgtg gcaggtggca gaagtggcag aagcctgcgt tcagcctgca cactggagtg
    29581 gcgatgtgga tacgctggca gatatggtgg tgaaaaccgc tcagcctggc gaccatattc
    29641 tggtgatgag caacggcggt tttggtggga tccatcagaa actgctggat ggtctggcga
    29701 agaaggcgga agctgcgcag taattcggcc tcagcctgat atagtgtgcg taggccggat
    29761 aaggcgttca cgccgcatcc ggcatttgag catagtgcct gatgcgacgc ttgatgcgtc
    29821 ttatcaggcc tacaggtgca ccgcatccgg caaaccatac tcacatcaac aacgaaaatt
    29881 acccttcatt ctccgccagt tcgcgcagat actggaaaat ctggcgtgcg gatttcggcg
    29941 gcttattccc ttctttctct ttcttcgcgt tacggatcag agtacgcagt tgctgacgat
    30001 cggcatcggg ccacagattt aatacctcag cgatggcgtc atcaccttga tcgatcaggc
    30061 gatcgcgcag gttttccagt ttatggaaca gcaccacctg ctggttgtga cggtttttca
    30121 gcttatccag cgcctgacgg atcggttcta catcgcgctg gcgcagcatc ttaccgatga
    30181 gctgcaactg gcggcggcga ccttccatct taatacgctg ggcgagctca atagccgcgc
    30241 gcagatccgc atctaacggg atcttatcca gcgcgttttt ccccagatca acaatttccg
    30301 cgccaaggcg ttttagctcc tcggcatcac gtttaatttc acttttactg acccagataa
    30361 tttcatcgtc ttcgtcttcg atgtcatcac cgggaacgtc gtcgagccag tcttcgggct
    30421 gcttagtcat ctcaggctcc ttaaaaaaag aggctaatgt taccagttaa gatgcgcact
    30481 gaaaaacggt tctctgttag acttcagaga aactctctac attatggcac ttgcaatgaa
    30541 agtaatctct caagttgaag cgcagcgcaa gattctggaa gaagcagttt ccactgcgct
    30601 ggagttggcc tcaggcaaat cggacggtgc ggaagttgcc gtcagcaaga ccaccggcat
    30661 tagcgtaagc acgcgttatg gtgaagtgga gaatgttgaa ttcaatagcg atggcgcgct
    30721 ggggatcact gtttatcacc agaaccgcaa aggtagcgca tcatccaccg atttaagccc
    30781 gcaggccatt gcccgcaccg tacaggcggc gctggatatt gcccgttata cctcgccaga
    30841 tccctgtgcc ggcgtggcag acaaagagct gctggccttt gaggcaccgg atctcgattt
    30901 gttccaccct gcggaagttt ccccggatga agccattgaa ctggcggccc gcgcagaaca
    30961 ggcagcatta caggcggaca aacgtatcac caataccgaa ggtggcagct ttaacagcca
    31021 ctacggcgtc aaagtttttg gcaacagcca cggcatgttg cagggttact gctctacgcg
    31081 tcattcgctc tccagctgtg taattgccga agaaaatggc gatatggagc gtgattacgc
    31141 ctacaccatt ggtcgtgcga tgagcgatct gcaaacgcca gagtgggttg gggccgactg
    31201 tgctcgccgt actttatcgc gcctgtcacc gcgtaaactc tccaccatga aagcgccggt
    31261 catttttgcc aatgaagtgg caaccgggct ttttgggcat ctggtggggg cgatagcggg
    31321 tggagcggtt taccgtaaat ctaccttcct gctggattcg ctgggtaaac aaattctgcc
    31381 ggactggctg accattgaag agcatccgca tctgctgaaa gggctggcat cgacgccatt
    31441 tgacagcgaa ggtgtgcgca ccgagcgtcg cgatattatt aaagatggca tcctgactca
    31501 gtggctgctg accagctatt cggcgcgaaa actggggctg aaaagcaccg gacatgcggg
    31561 cggtattcac aactggcgga ttgccggaca agggctaagc ttcgaacaaa tgctcaaaga
    31621 gatgggcacc gggctggtgg tgacggagct gatgggccag ggcgtgagtg caattaccgg
    31681 tgattattcc cgtggtgcgg cgggcttctg ggtagaaaac ggcgaaattc agtatccggt
    31741 tagcgaaatc accatcgcag gtaatttaaa agatatgtgg cgcaatattg tcaccgtcgg
    31801 taacgatatt gaaacacgca gtaatataca gtgtggttct gtgctgttgc cggagatgaa
    31861 aatcgccggg cagtaaaaaa ctggcgcgac ctgccgcgcc aaatcttcat aataaaaaag
    31921 gaagtgagca atgcgtaaaa gcctgttagc tattcttgca gtctcctcgt tggtattcag
    31981 ttcggcgtcg tttgccgctg atcttgaaga caatatggaa accctcaacg acactttaaa
    32041 agtggtcgaa aaagccgata acgcggcgca agtcaaagac gcgttaacga agatgcgcgc
    32101 cgcagcgctg gatgcgcaaa aagcaacgcc gccgaagctc gaagataaat caccggacag
    32161 cccggaaatg aaagacttcc gtcacggttt cgatattctg gttggtcaga ttgacgacgc
    32221 gctgaagctg gcaaatgaag gtaaagtaaa agaagcgcag gctgccgcag agcaactgaa
    32281 aacgacccgc aacgcctatc accagaagta tcgttaattc ctcatttccc tgttgcctgc
    32341 actcaggtaa cagggaactt atcatcgcaa atgatgcacc acctgattgc tgctgccgcg
    32401 ccagatcagg gaagggtctt ttaaattctg cacaaatttg ccgtcgacca gtacgttaat
    32461 caaatcaaca acctgcattt gcgcagcgtt gagatcgtcg agtttatagc ctgtccacac
    32521 ccagatatct ttatccggac actcggcgcg gatgcgtttt accagtttca gaatatccgg
    32581 cacgttttgc ggatgcagcg gatcgccgcc ggagagggaa atcccctggc gtttgatacg
    32641 agtgtcattc agatcgttaa tgatctggtc ttccattgct ttggtaaatg gctgaccaga
    32701 atttacccgc catgtgcttt tgttatagca accggggcat tcatgaacac acccggagac
    32761 aaacagggtg cagcgagtgc cggggccgtt gacgatgtcg acaggatagt actgatgata
    32821 attcattatt tcgcctggct tatcagtccg cgtgtaggct gcatccggta atcaatgcct
    32881 gatgcgacgc tgtcgcgtct tatcaggcct acacagccgt tgccaaatgt aggccggata
    32941 aggcgtttac gccgcatccg gcatttgctt agcgcagagt gaagattaac ctatctgccc
    33001 attccccaaa tgtttaacgc ggcgcttaac ttcttcctgc ttaccagcgt taaacggacg
    33061 tgcatccggg ctacctaaat atccgcacac gcggcgagtt accgacacac gggaggcgtc
    33121 atggttacca catttcgggc aagtgaagcc tttgctggtg cactcgaact caccggtaaa
    33181 gccacactcg tagcactcat caatcggtgt attggtgccg taatacggta catgctgata
    33241 gctgtaatcc cagacatctt ccagcgcttt caggttgtgc tgaatgtttg gatactcgcc
    33301 gtagcaaatg aaaccaccgt tcgccagcgg cgggtaaggc gcttcaaagt cgatcttgtc
    33361 gtacgggttc accttcttct ccacatcaag gtggaaactg ttggtgtagt aacctttatc
    33421 ggtcacgccc ggcaccacgc caaactcagc agtatcgaga cggcagaagc ggtcgcacag
    33481 gttttcactc ggcgtgctgt agagactgaa accataaccc gtttcttctt tccactgatc
    33541 cactgcctga cgcagacgtt caacaatcgc gatacctttc gcgcggagct gctcgttgtc
    33601 gtaaacatgc tcgccgccga acagcgcgtt aatggtttcg tggatgccga tgtaacccag
    33661 cgaaatagac gcacgaccgt ttttgaagat ttcagaaaca tcatcgtcag cattcagacg
    33721 cacgccacaa gcaccttcca tataaaggat cggggccacg cgcgctttca cgccttccag
    33781 acgagcgata cgggtcatca gcgccttacg tgccagcacc agacgttcat ccagcagctt
    33841 ccagaaggtg gcttcatcgc cttttgcttc cagagcaata cgcggcagat tcaggctgat
    33901 cacgccgagg ttgttacgac catcgtggat ctgctcgccg ttttcatttt cccacacgcc
    33961 gaggaagctg cggcagccca tcggggtttt aaacgaaccg gtgactttca ctacctgatc
    34021 gtagttcagg atatccggat acatgcgctt gcttgcgcac tccagcgcca gctgtttgat
    34081 gtcgtagttc ggatcgcctt ttttatggtt cagaccatcg cgaatcgcaa acaccagttt
    34141 cgggaacacc gcagttttac ggtttttacc gagacctgcg atacggttac gcaggataga
    34201 ttcctgaatc aggcgcgatt cccagctggt gcccagacca aaaccaaaag ttacaaacgg
    34261 cgtttgaccg ttggcggtat gcagggtgtt tacttcgtac tccagcgact ggaaggcatc
    34321 gtagcactct ttaatggtac gagagttagc gtagccttct gcgtccggga tgctccactc
    34381 ttctgcggtc ttgcgatgtt tgttgtagct ggcggtgaca aacggtgcca gcacttcatc
    34441 gatacggtta atggtggtgc cgccataaat atggctggca acctgagcaa taatctgcgc
    34501 agttaccgcg gttgccgttg agatcgactt cggcggttca atctcggcgt tccccatttt
    34561 aaagccctgg gtcagcatgc ctttcaggtc gatcaacatg cagttgaaca tcgggaaaaa
    34621 cggtgagtaa tcgagatcgt gatagtgaat atcgccacgc tcatgtgcct gcaccacgtc
    34681 acgcggcagc aggtgctgac gtgcatagtg tttagccacg atcccggcca gcaggtcgcg
    34741 ctgggttgga atcaccttgc tgtctttgtt ggcgttttcg ttgagtaacg aggcgttggt
    34801 ctgctcgacc agaccacgga tctcctggtt caggcgaccg cgtttttcac gttcaatgtc
    34861 gcgatcgtga cggtactcga tgtaagcgcg agccagttgt ttgtatggac ccgacatcag
    34921 ctggttttca actgcggtct ggatctcgtt gatatccacc tggttgcggc cctgcatctg
    34981 ctcgctgaca accgcggcaa cagtggcgca ataatcggca tcatcgactt ccgctgcttt
    35041 agctgcacgc agaatcgctt ctttgatgcg ctctgattta aacggcactt tgcagccgtc
    35101 tcgtttcatc acatgcggtg tcatgatcgc tccatatttt taagaacagg ttatccacag
    35161 aaattgggaa aggcgttttc cggttttttc gtttcgtttt ccggtgcttt ccgcaatcgc
    35221 catccgctta tccacaacgc cgcacctttt tcgtggggag ctgtagtagc aattatagtc
    35281 gattaataca acatattggg ttgggacgca ttttaaagtc tatatatagt gctttgcatc
    35341 aaggatgttt taactttttt tgatgtagct caaagtaaaa agcagagcgt acggatgacg
    35401 ggcgctacag cgttatgtaa attttttaat gaatttgctg gttgaaaaat caacaaaaac
    35461 aacatgctga cagacaaaac cccggaatga ccggcattac cggggcttag ggaagattta
    35521 cttctgtaac caccagacag cctcaaaagg ccgtaaagtc atggcacagg gttgtggtga
    35581 ggcttcttcg tagttatgca tcacaagttg ccagttgccg cgcattttcc ctggctgcca
    35641 gggttggatc tcacggctaa ggttggcaat gaccagcaag gtttgcccct tccattcacg
    35701 gcgatagcac cacaatacag ggctgtttgg cagcagatcc tggtaattgc cccatgtcag
    35761 gatggcttct tgcttacgca gtgcgattaa cttttggtag gtgtaaaaca ccgaggaatc
    35821 atcggccagc gcggcttcta cgttgatttg ttgatagtta tcgcccaggc caatccacgg
    35881 ttcgccagcc gtaaacccgg cattatcgcc gttgctccat tgcatgggcg tgcggctgtt
    35941 gtcacgggat ttactggcga ggattgccaa taactcgtcg gcatcacgcc catcgttgcg
    36001 cagctcggca aacatattga ggctctccac gtcgcgatag tcagtaatgc gcgagaaatg
    36061 tgggttggtc atgccaatct cttcgccctg gtagatatac ggcgttccct gcatgccgtg
    36121 cagcaccatc gccagcattt ttgccgcagg cacgcggtat tcaccttcat caccaaagcg
    36181 agaaacaatg cgcggctgat cgtggttaca ccagaacaag gcattccatg ccacgttgtg
    36241 cattccttgt tgccagtggc ggaacaatgt tttcaacgcc acaaagtcag gtttagccag
    36301 cgtccatttt tcaccaccgg gataatcgac cttcaggtga tgaaaattaa aggtcatcga
    36361 caattcactg cctgtcagtg ccgcgtatcg ctggcaatgc tcaaggctgg tggaggacat
    36421 ttcacctacg gtcattaacc cgcgtggcgt aaacacatcg cggttcatct cgtgcaaaaa
    36481 ctcgtgtgct cgtggcccgt cggtgtagaa gcgacgcccg tcgccatcca ggtcttcagg
    36541 gaaacgcggg tctttggaga tcagattcac cacatccagg cgcaacccgt cgaccccacg
    36601 atcggcccag aattcacaga cttttttcag ctctgcgcgt accgctggat tctcccagtt
    36661 gagatctgcc tgttctggtg caaagagatg caaatagtac tgttcgcttt ccgcatgcca
    36721 gcgccacgca ctaccgccaa attttgaacg ccagttgttc ggtggcgttt ctggttcgcc
    36781 atcgcgccag atataaaact ggcggtaagg gctttctttg ttcagcgcct cgcgaaacca
    36841 ggcatgttgg gtagaggtat ggttaaacac catatcgaga atgatacgaa tcccgcgcga
    36901 ttttgcctgc gtcaccagtt cgtcaaaatc gtccagcgtg ccgtaggtgg gatcaatcgc
    36961 cgtatagttc gctacatcgt aaccgttatc gacctgggga gagacataaa agggggttag
    37021 ccagatggca tcaacgccca gtttatgcag atagtccagg cgttggataa cgccacgtaa
    37081 atcgccggtg ccgctacccg tggtgtcctg aaaactcttt ggataaatct ggtagataac
    37141 gccgttttgc caccagtggg gaagattagt cattacgtta ttcctgcaaa tgcgaggggg
    37201 cgcaattgcg ccccgaagaa aattaaacaa tgtccagcgt gcccaggcgg tatttccgct
    37261 gatagataaa cgaggtgagt acaatcggga tgatgatggc gatagccatt gccagcgcaa
    37321 acacctgcca gtagctcggt tgaatcgaga gaattcccgg caggccgcct acgccgatac
    37381 cattcgccat aacgccgttc aggccgcata gcaatcctgc cagaccagaa ccaatcatcg
    37441 cgcacagcat cgggaagcga tatttcaggt tgatgccgta cattgcaggc tcagtgaccc
    37501 caagccaggc ggagatagcg gcaggcacgg agatctcgcg ctcattgtgc ttgcggctgg
    37561 aaatgataat gcctattacg gcggagccct gagcgatatt cgacagcgca atcagcggcc
    37621 acactggcgt gccacccatg ctttgaatca tctgcaaatc aatagcaagg gtggtctggt
    37681 gtacgccggt gatcaccagc ggcgcgtaca ggaagccaaa caatgccgca ccaatcggag
    37741 caaagctgcc ggtcatcagg tgacgtaccg caaaggcaac gccatcgcca atcatgcgac
    37801 caaacggacc aatcagcgca tgggcgagga acaccgcgag gatcagcgaa cagacgggta
    37861 ccaccaccag atagaggtaa tccggcacga tgcgtttaag gcgagtttca ataacgccca
    37921 gcgccagtcc ggctaacagt gccgggatca cctgcgcctg atagcctact ttggcgatgc
    37981 tgaacatgcc aaagtcccac acttccggca gctgctgccc gagcagataa gcgttcatca
    38041 gctgtggaga aaccagtgtc acgccaagca cgataccaag gatcggcgtg ccgcccattt
    38101 ttttcaccgc tgaccagcaa ataccgaccg gcaggtagaa gaagatcgcg tcaccgatca
    38161 accacagaaa atcgtagatc gtttgcaggg aagggtacat ttgcgccagc gtctgaccgt
    38221 tgctcatggg caaatcgccg atcacattgc gaaaaccgag gatcaaaccg ccgctgatca
    38281 acgcgggcag caacgggaag aagatctccg cgaaatgaga gatcaactgc tcatgccatt
    38341 tcatattctg ccgggcggct ttttttacct gctctttatc aacctgcgcc tgtccggttg
    38401 acgcaatcag tgcttgatag taatcaccca cgttggtgcc aatcaccacc tgaaattgcc
    38461 cggcattggt gaaacagcct ttcaccatgg ggagttgctc aatttctttc ggtctggcat
    38521 tggccggttg gttgaggaca aagcgcaggc gagtaataca gtggctcacc gtcgcaatat
    38581 tgccgcgccc gccgaccagt tcaatcaacc gatcgatatc cgtttggttt attttgctca
    38641 tcataaagcc ccatggcaga tgacattttt ggttggctgc agaatatatt gcgcggaaaa
    38701 atttaaaaac gggaacgttc ccgaaacgca gcgaagatca caatttatcg ttcaggtaac
    38761 gatcaggaca gggtggcggg gatgatgatt tgttgcggtt cgctgcgccc ggttacctgt
    38821 gcgatcaatt ggcaggccgc ctggcgtcca gcttcggcgt aaccaggatc tacggtgacg
    38881 atctccggat gaaggaattt cattaacggc gtattaccga cgctcgccag ttgcaaggtg
    38941 tcgatgcgtt gctcttgcag gtatttactt gcgccaagtg ccagcgtgtc ggttgcgcac
    39001 agtaacgcag tagtttcagg cgtaatcact tttgctacgt tctcatagcc ttgcttcata
    39061 gcaagccctg gcagagcggc aacgggatgc agtttatgcg ctttgcagaa cgccaggtag
    39121 gcttcgtgac gtcgcttacc ggttgtcacg tcactatgcg gcacgccgag ataactgata
    39181 ttacgatgcc cctggtcata cagccgttgc atcaggatct tgattgcccc ttcgtcgtca
    39241 taacagaccg aagcaaagcc ttttgcgtca cgcgccagca gaaccagcga tgactgccag
    39301 tgggctaaca tttcttctgt tatgccagta aaaccgaaca gcactacgcc gtcgatatta
    39361 cgccgtttca gcacccccaa atgttcggca actaattgcg gggaaaactg actttccatc
    39421 atgattgggt cgtaaccttg ttcatagaac gctggcagca tggtttgaac ggcgagattt
    39481 tctgacaacg aatccaggcg ggtaacaatg atggcgacca ctttatcgct ttgcccacgc
    39541 atagcgcgcg cagagcggga aggggaaaat ccatgctgat tcatcactgc ttcaacacgc
    39601 tcgcgggtgc gctggctcac gccgctttcg ttattcagca cccgggaaac cgtagatttc
    39661 cccacgccgc ttaagcgcgc gatgtctttg atggtcagcc gattttgcat cctgttgtcc
    39721 tgtaacgtgt tgtttaatta tttgagccta actttacccg tgcattcagc aatgggtaaa
    39781 gtctggttta tcgttggttt agttgccagc aggtattata tcgccataga tgctacgaat
    39841 attattggat tctccttatt atttgcggcg cttttttcac ttaccggagg ttatatggaa
    39901 cctgatccca cgcctctccc tcgacggaga ttaaaacttt tccggtaagc ccgtcttttc
    39961 acggcgttac cggatgcgta aggccgtgac gttttaacgt ccctgctcag ctttattacc
    40021 ttcaggtaag gcttcgccac gcctgaagac atttctgtac tgtttcagac agtgcggagg
    40081 gattccttat gtttaaagaa atttttaccc ggctcattcg ccatttacct tcccgtctgg
    40141 ttcatcgcga tccattgcct ggcgcgcagc agacagtgaa tacggcggtc ccgccgtcct
    40201 taagtgcgca ttgcctgaaa atggcggtga tgcccgaaga agaattatgg aaaacgttcg
    40261 acacccatcc ggaagggtta aatcaggcgg aagtggaatc tgcccgcgaa caacatggtg
    40321 aaaataaatt acccgcacaa caaccgtcgc cgtggtgggt acatttatgg gtctgctatc
    40381 gcaacccctt taatatttta ctcaccattc tcggcgctat ttcttacgcc acggaagatt
    40441 tatttgccgc gggcgttatc gcgctaatgg tcgctatttc aacgttgctg aactttattc
    40501 aggaagcacg ttccactaaa gcggcagatg ccctgaaagc gatggtcagc aataccgcga
    40561 cggtgctgcg cgtaattaac gacaaaggcg aaaatggctg gctggagatc ccgatcgacc
    40621 agctggtgcc cggcgatatt ataaaactgg cggcgggaga tatgatcccg gcagatttac
    40681 gtatcttgca ggcgcgggat ctgttcgtcg ctcaggcgtc gttaaccggt gagtctctgc
    40741 ccgtagaaaa agccgctacc actcgccagc cggagcacag caatccgctg gagtgcgata
    40801 ccctgtgttt tatgggcacc accgtggtga gcggcacggc acaagcaatg gtgattgcta
    40861 caggagccaa cacctggttt ggtcaactgg cggggcgtgt tagtgagcag gaaagcgagc
    40921 cgaatgcctt tcagcagggg atcagccgcg tcagtatgct gctgattcgc tttatgctgg
    40981 tgatggctcc ggtggtgttg cttatcaacg gttacaccaa aggcgactgg tgggaagcgg
    41041 cactgtttgc gctttcggtc gcggtaggct taacgccgga aatgttgccg atgattgtta
    41101 cctcgacgct ggcgcgcggc gcagtaaagc tgtcgaaaca gaaagtgatc gtcaaacatc
    41161 tggatgctat tcagaacttt ggcgcaatgg atattctgtg cactgataaa accggcaccc
    41221 tgacacagga caaaattgtg ctggagaatc ataccgatat ctccggtaaa accagcgaac
    41281 gcgtgctgca tagcgcgtgg ttgaacagcc attatcagac cggacttaaa aacctgctcg
    41341 atacagcggt gctcgaaggt acggatgaag agtcagcgcg ctcgctggcc agtcgttggc
    41401 aaaaaattga tgagattccg tttgatttcg agcgtcgccg gatgtcggtg gtagtggcag
    41461 aaaataccga gcaccatcag ctggtttgca aaggtgcatt gcaggaaatc ctcaatgtgt
    41521 gttcgcaggt gcgtcacaat ggcgagattg tgccgctcga tgacatcatg ctgcgtaaga
    41581 ttaagcgggt tactgatacg ctgaatcgtc aggggctgcg cgtggttgcg gtggcgacga
    41641 aatacctgcc agcgcgtgaa ggagattacc agcgggcgga tgaatccgac ctgatcctcg
    41701 aaggatatat tgctttcctt gatccgccaa aagagacaac tgctccggca ctgaaggcat
    41761 taaaagcgag tggaattacc gtaaaaatcc ttactggcga cagtgagtta gttgcagcga
    41821 aagtgtgcca tgaagtgggg ctggacgcgg gagaggtggt cattggtagt gatattgaaa
    41881 cgctatctga cgacgaactg gcaaatctcg cacagcgcac cacgctgttt gctcgtctga
    41941 cgccgatgca taaagaacgc attgtgacct tactgaagcg cgaagggcat gtggttggct
    42001 ttatgggcga tggtattaat gatgcgcccg ccttacgcgc tgcggatatc ggcatttctg
    42061 tggacggcgc ggtagatatt gcccgtgaag cggctgatat catcctgctg gaaaaaagcc
    42121 tgatggtgct ggaagagggg gttattgaag gacgtcgcac tttcgccaac atgctgaaat
    42181 acatcaaaat gacggcgagc tccaacttcg gtaatgtgtt cagcgtgctg gtggcgagtg
    42241 ctttcttgcc cttcctgccg atgttgccgt tacacttgct tattcagaac ctgctgtatg
    42301 atgtgtcaca ggtggcgatc ccgtttgata acgtcgacga cgagcaaatt caaaagccgc
    42361 agcgttggaa tccggcggat ctggggcgct ttatgatctt cttcggaccg atcagctcga
    42421 tcttcgatat tctgacgttt tgcctgatgt ggtgggtatt ccatgccaac acgccggaaa
    42481 cgcaaacgct gttccagtcg ggatggtttg tggtgggctt actgtcgcaa acgctgattg
    42541 tgcatatgat ccgcacccgc cgtgtgccgt ttattcagag ctgtgcatcg tggccgttaa
    42601 tgatcatgac cgtgatcgtg atgattgtcg ggatcgcatt gccgttttca ccgctggcca
    42661 gttatctgca attacaggcg ctgccgttaa gctatttccc gtggctggtt gcgattctgg
    42721 cagggtatat gacattaacc cagttggtga aagggttcta tagccgtcgt tacggctggc
    42781 aataaagaat aaactgggca cgatagcccc gattcagatt gcagacaaag taagctttgt
    42841 tcatgccgga tgcggcgtaa atgccttatc cggccaacaa attcaataaa ttgcaggaat
    42901 cacgtaggcc tgataagcgt agcgcatcag gcgattttgc gtttgtcatc agacttaatc
    42961 cgggcatgat agcccggatt tccatcaaga ttagcgacga acagcgatcg cttcgatctc
    43021 aatcttcacg tctttcggca gacgggcgat ttcaacgcaa gaacgtgccg ggaaggtggc
    43081 gttgtgttcg gtgaagaagg cttcgtaggt agcattaacg gtagcgaagt cgttcagatc
    43141 tttcacaaac acggtggttt taacgatgtc gcccactttc aggccagcgg cttcgacgat
    43201 cgcttttacg ttatccagcg actgacgtgc ctgtgcagcg acgtctgccg gtacttcacc
    43261 cgttttcgga tttaccggga tctgaccgga ggtgatgatc atattgccca gatcaacgcc
    43321 ctgtacgtaa ggaccgatag ctgccggtgc attttccgtc gcgatagttt tgctcatgat
    43381 ttctccttta ttacagcggt aaaaagtctg gctcattata gggagccaga cttttattac
    43441 caaccgcaat taattggcca gcaccacatt atgggaaaac tctttttcac agtatttgca
    43501 tttgagcgcg atgtcattgg cgcgttttcg cacggcaaag ctggaagaaa ccggttcggc
    43561 atggctgata cagttgctgt tcgggcagac cagcacattg tcgatgcgct ccggcagact
    43621 ggggcgcgat ttgcccacca cttcatagtt gtcgatacgg ttaaccgtgg cttgcggcgc
    43681 atacaatgcc agttgatcta cctggtcttc actcaaaaag gtattttcga ttttgatcag
    43741 atctttgcgg cccatctcgc cagaaggcaa gttcagaccg atggtgatgc gctgatccgt
    43801 ttcggtcagc ttgaacagac tcaacagctt aaaaccgatc tgggcgggga tatggtcaat
    43861 taccgtgccg cgtttaatag cttcaacctg caatttatta tcgtgtgtca tctctatttc
    43921 cccttacagt accagatcgc gattcagaac cagtgccagt aacgcctggc gagcgaatat
    43981 cccattgcct gcctgctgga agtaccaggc gtgtggcgtt ttatccacat cggtggcaat
    44041 ctcatcaaca cgcggcagcg gatgcagcac tttcatattg gctttggcgt tgtggagatc
    44101 gctggcgcga agaacaaact gcgcttttac gttggcgtat tcggatgggt ccaggcgctc
    44161 tttttgcacg cgggtcatat acaggatgtc tacttccgcc atcacttctt caatagagct
    44221 gtgcagactc cagacgatcc ctttttcatc aagcatatcc agaatgtatt gcggcattgc
    44281 cagcgcgtcc ggcgcaatga agtaaaaacg gttgccgtcg aacttcgcta acgcctgagt
    44341 cagggagtga acggtgcggc catatttcag gtcaccaacc attgcgacgt ggagattgtc
    44401 cagacgcccc tgggtttcct gaatggtgaa taagtccagc aaggtttgcg tcggatgttg
    44461 gttggagcca tcaccggcat tcagtaccgg tacattgccg gaaaactcgg tggccaggcg
    44521 cgccgcacct tcctgcggat gacgcatcac tattgcatcg acgtaagtgc tgataaccga
    44581 aatggtatcg gccagcgttt cgcccttttt acccagtgat gtattggcgc tgtcggagaa
    44641 gcccaccacg ctggcaccca ggcggtgcat ggaagtttcg aaagagaggc gggtacgggt
    44701 agaggcttcg aagaaacagc tggcaatgac tttgtgcttc aacagctctg gttgcgggtt
    44761 tgctttcagt ttcgccgctg tcgccagcac cagattaagg tcatcgcgac taaggtcgtt
    44821 tatggaaatg atatgtttct gatatagcgg attagccatc ttttatctcc tgacgcctgg
    44881 gcaaaaaaaa gcccctcgat tgaggggctg ggaatgagtg atcaacggga agaaaaacgg
    44941 caggccagcg tcttttttca gacgcggtaa gacaaaatgt cgaacacact gaaccataca
    45001 tcctcccggc aaattgtccg gcattatact catcgtcaga agcggtgcaa gcatttgatg
    45061 caatattttg tcagcgcaaa cggtttattt gaattataag tcaaaatata tgcattttta
    45121 tttgctgtga ttctggaggg gaactgtcgt tcggtatcaa taattgcaga catttcctgc
    45181 ttttttcttt ttcactttca cgcaatcaga tatgcatttt attccattca tccgacttat
    45241 agggcggagt gtgaaaacga acggctaaca ctattgctta ctgcgcaggg atgcgcgcta
    45301 tcactttaat ttcaaaatca aagcctgcca gccatgtaac acccaccgcc gtccagtttg
    45361 gataaggtgg ggcgctaaat atttcatttt tcaccgtcat gatgtcttca aattgttttt
    45421 ctggatcggt atgaaagctc gtaacatcaa tgatatcgtc aaaagtgcat cccgcagcag
    45481 ccagggtcgc atgcaaatta tcaaatgcca gtctgacttg ttgctgaaaa tcgggttctg
    45541 gtgttccgtc ctctcgactt cctacttgcc cggaaacaaa cagcaaatcg ccggagcgaa
    45601 tagccgcaga ataacgatgt tcagcataca gtgaatgtcg gccagcaggg aaaacagcgg
    45661 ttctttctac catttggtta tcctcaagat ttacgacatg aacagaagat ttatatttac
    45721 caggagccgc ttttagcgga cgacgtgagt aaacaaaacc cagacatcat ggataatggc
    45781 tgggcttaat tgagcgtagt cggttatgcg ccaaacgcgc catcaatggt atgcatcgcg
    45841 ccggtaacaa agctggcttc tggccctgct aaccatgcga ccataccagc gacctcttcc
    45901 ggttgcccat gtcttttgat agccataaaa ccatgcaaca tatcgcgcat tggcccgttg
    45961 gcgggattag cgtcggtatc aattggccct ggctggacga cgttgatggt gatcccacgc
    46021 ggtccaaaat cacgggccag cccgcgcgcc atgccttgca gggcagattt gctggcggca
    46081 taagcagcca tgcctgcaac aggcatacga tcgccattca cggagccgat gattaagatg
    46141 cgcccgcctt cgggcatctg ccgggcggct tcaacggagg catggtaagg agcatgaata
    46201 ttgattttga aaaggcgatc aatatcgtcg gcatttaatt ccagggcatc gccaaagacg
    46261 ccaatacctg catttaccac gaggatatcc aatgcgccgc tcttacgaac gacatcaata
    46321 acagcgtctc tgtcagcact atctgtgaat actgctgtcg ctcccgtctc ttgtgccagg
    46381 cgttcagcgg catctttcga ccccgcatag gtgaatcgta cattggcccc atcggtgacg
    46441 aaatgacgta cgatagcggc accgattcca cggctaccac cgaggatgag aactgtctta
    46501 cctgtaaaag cgcccataag gactccttga tttattatgt aacatgcatt acaaaactgt
    46561 tttaactttc tgtcaacaag ttttgtaatg gtcactaaaa aacaatctcg cgttccaggt
    46621 cgtcccagac gtttcgctcc tgagcaggca gtctctgcgg caaaagtgct ttttcaccaa
    46681 aaaggtttcg atgctgtcag tgttgctgaa gttactgatt atcttggtat taaccccccg
    46741 agcctctacg cggcttttgg cagtaaggct gggttattta gccgtgtact caatgaatat
    46801 gtcggtacgg aagctattcc gcttgccgat attcttcttg atgatcgtcc ggtaggcgag
    46861 tgcctggttg aggtattaaa agaagcggcg cgcagatata gccaaaacgg cggctgcgct
    46921 ggctgtatgg ttcttgaagg tattcatagt catgatccac aagcgcgtga tattgccgtt
    46981 caatattatc acgccgcaga aacgaccatt tatgactata tcgccaggcg gcatccacaa
    47041 agcgcacaat gtgtgactga ttttatgagt accgtgatgt cagggctttc tgcgaaggca
    47101 cgggaggggc actccatcga acaactctgt gcaacagctg ccctggcggg ggaagcgata
    47161 aaaactattc tcaaggagtg atgctggcct tgatccgaaa ggcgggaacg cgcctgccga
    47221 taagttgtga taagacaata attcacgcgt taaggctggc ggaattgatc atcttttcgt
    47281 ataacgatag aaatgaaaca ttgttttaat taaggagtgg aaaagatgat catcggaaat
    47341 attcataatc ttcagccgtg gctaccccag gagttacgcc aggcgattga gcatgtcaaa
    47401 gcgcacgtta cggcagaaac gccaaagggt aagcacgata tcgaaggcaa tcgtctgttt
    47461 tatcttatct cggaagatat gaccgagccg tacgaagctc gccgtgcgga gtatcatgcc
    47521 cgctatctcg acattcagat tgtgttaaaa ggtcaggaag gcatgacctt cagcacgcaa
    47581 cctgcaggca cgccggatac cgactggtta gctgataaag acatcgcatt tttgccggaa
    47641 ggcgttgatg agaaaacagt tatccttaat gaaggtgatt ttgttgtgtt ttatccgggg
    47701 gaagtgcata aaccgctgtg cgcagtgggc gcgccagccc aggttcgcaa agcagtagtg
    47761 aagatgctga tggcgtgatg acttttcgcc gtaaataact ccaggtttac ggcgagtttg
    47821 tgaaaagagc gttttttgat atttttttgt gagtaaaatt tgtaatgctt agacgttctt
    47881 attaactcaa ggagttcgtc atgagcaaaa tatcagattt gaattattct caacacatta
    47941 cattagccga caattttaaa caaaaaagtg aagttttaaa tacctggcgt gttggaatga
    48001 atgattttgc tcgtaatgcc gaggggcagg ataacacaag aaatatcctc gatcctaaga
    48061 catttttgga gtttttggta aaaatattta ccctgggtta tgtggatttt agcaaacgct
    48121 ccaacgaagc gggaagaaat atgatggctc atattgagtc ctcatcttat atcaaaaata
    48181 atgatggcag tgagataatg aagtttgtta tgaataatcc tgaaggggag cgagcggatt
    48241 tatctaaggt ggaaatagaa attacacttt ccactatcac tactatgggg actcgtcaag
    48301 gacatacggc tattatattt ccacaacctg atggtttgac taatcgttat gaaggaaagt
    48361 cctttgaaag aaaagatgag agttcattac acctgattac taacaaggtt ctggcgtgtt
    48421 atcaacgtga agctaacaag gaagtggcgc ttctattaaa taatcatcag aagttaaatt
    48481 atcgtcagaa gttaaataat tcgcaggggt taaataattc acaggggtta aataattcgc
    48541 aggggttaaa taattcgcag gagttaaatg attctcagga gttaaatgat tctcaggact
    48601 taaataactc gcaggtgagt tgtaaaggtt cagttgattc tacgattacg gatttattag
    48661 aaaaaccatt gaataatgca ttattagcaa taaggaaaga acatctgcta ttaatgcctc
    48721 atgtatgtga tgaatcgatt tcatacttac tgggcgaaaa aggtatactt gaagaaatag
    48781 ataagctcta cgcattaaat gatcacggaa ttgataatga caaagtaggt aacaatgaaa
    48841 ttaatgacat caaagttaac ctgtctcata ttcttattga ttccttagat gatgcaaagg
    48901 ttaaccttac accggtcatc gattcgattc tggagacttt ttcaaaatcc ccatatatta
    48961 atgatgtaag aatactggat tggtgtttta ataaaagtat gcaatatttt ggtgattctg
    49021 aaaagataac gcatgcatgc tccgtgatga gtcatattga ttttgattgc aatcaatcta
    49081 aaatagctga gactttattt ttcaatctcg ataaagaacc ctataaaaat agtcgtgaat
    49141 tacaggaatt gatttgggag aagttggttg catatgtcaa tgtttttaat ttaagtaatc
    49201 aagaaaaatc acgcttaata ctaaggttat ttgatgatgt taagttgcta tttaatgaag
    49261 tgcctgtcag cattttggta aatgatattt ttttga
//
LOCUS       DACAOP010000024        47972 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.024, whole genome shotgun sequence.
ACCESSION   DACAOP010000024 DACAOP010000000
VERSION     DACAOP010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47972
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.024"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..353
                     /gene="nrdR"
                     /locus_tag="IT892_001557"
     CDS             <1..353
                     /gene="nrdR"
                     /locus_tag="IT892_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HAP3134787.1"
                     /translation="CNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKR
                     PVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFE
                     DIKEFGEEIARLED"
     gene            357..1460
                     /gene="ribD"
                     /locus_tag="IT892_001558"
     CDS             357..1460
                     /gene="ribD"
                     /locus_tag="IT892_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HAP3134788.1"
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
                     RAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVASMQD
                     PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
                     TAMASGESQWITSPQARRDVQLLRAQSHAILTSSATVLADDPALTVRWSELDEQTQAL
                     YPQQNLRQPIRIVIDSQNRVTPVHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHK
                     GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGSDARGLC
                     TLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
     gene            1549..2019
                     /gene="ribE"
                     /locus_tag="IT892_001559"
     CDS             1549..2019
                     /gene="ribE"
                     /locus_tag="IT892_001559"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HAP3134789.1"
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
                     KDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
                     HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            2039..2458
                     /gene="nusB"
                     /locus_tag="IT892_001560"
     CDS             2039..2458
                     /gene="nusB"
                     /locus_tag="IT892_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAP3134790.1"
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
                     AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            2536..3513
                     /gene="thiL"
                     /locus_tag="IT892_001561"
     CDS             2536..3513
                     /gene="thiL"
                     /locus_tag="IT892_001561"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HAP3134791.1"
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
                     FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
                     PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
                     SDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNR
                     GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP"
     gene            3491..4009
                     /gene="pgpA"
                     /locus_tag="IT892_001562"
     CDS             3491..4009
                     /gene="pgpA"
                     /locus_tag="IT892_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAP3134792.1"
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
                     FIGHHWPLGILS"
     gene            complement(4063..5037)
                     /gene="yajO"
                     /locus_tag="IT892_001563"
     CDS             complement(4063..5037)
                     /gene="yajO"
                     /locus_tag="IT892_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414953.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxyxylulose-5-phosphate synthase YajO"
                     /protein_id="HAP3134793.1"
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
                     ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGR
                     LTRPWGETTARLVSDEVGKNLYKESDENDAQIAERLTGVSEELGATRAQVALAWLLSK
                     PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVVGFK"
     gene            complement(5217..7079)
                     /gene="dxs"
                     /locus_tag="IT892_001564"
     CDS             complement(5217..7079)
                     /gene="dxs"
                     /locus_tag="IT892_001564"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAP3134794.1"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVILNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
                     KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIY
                     STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
                     PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
                     LNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA"
     gene            complement(7104..8003)
                     /gene="ispA"
                     /locus_tag="IT892_001565"
     CDS             complement(7104..8003)
                     /gene="ispA"
                     /locus_tag="IT892_001565"
                     /EC_number="2.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="HAP3134795.1"
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
                     KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     VKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQAL
                     DLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQ
                     LAEQSLDTSALEALADYIIQRNK"
     gene            complement(8003..8245)
                     /gene="xseB"
                     /locus_tag="IT892_001566"
     CDS             complement(8003..8245)
                     /gene="xseB"
                     /locus_tag="IT892_001566"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015571292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAP3134796.1"
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     gene            8451..9899
                     /gene="thiI"
                     /locus_tag="IT892_001567"
     CDS             8451..9899
                     /gene="thiI"
                     /locus_tag="IT892_001567"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAP3134797.1"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
                     EGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTE
                     QEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNK
                     TWLLWCERGVMSRLQALYLREQGFNNVKVYRP"
     gene            complement(9953..10543)
                     /gene="yajL"
                     /locus_tag="IT892_001568"
     CDS             complement(9953..10543)
                     /gene="yajL"
                     /locus_tag="IT892_001568"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414958.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase YajL"
                     /protein_id="HAP3134798.1"
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLA
                     ITCSRDVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
                     AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWLDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(10506..11417)
                     /gene="panE"
                     /locus_tag="IT892_001569"
     CDS             complement(10506..11417)
                     /gene="panE"
                     /locus_tag="IT892_001569"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP3134799.1"
                     /translation="MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVET
                     DGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGT
                     IEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
                     PDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIERE
                     GHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVP
                     ENTRLFEMVKRKESEYERIGTGLPRPW"
     gene            11585..12076
                     /gene="yajQ"
                     /locus_tag="IT892_001570"
     CDS             11585..12076
                     /gene="yajQ"
                     /locus_tag="IT892_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414960.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide binding protein YajQ"
                     /protein_id="HAP3134800.1"
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
                     SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
                     ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
                     FRD"
     gene            complement(12204..13568)
                     /locus_tag="IT892_001571"
     CDS             complement(12204..13568)
                     /locus_tag="IT892_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414961.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3134801.1"
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
                     KLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHILLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
                     MKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVAIGGSLGGWINGMFDGQGVFLAGAMLAAVWLTVASTMKEPP
                     YVSSLRIEIPANIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFEIEQA
                     IRQA"
     gene            complement(13717..14607)
                     /gene="cyoE"
                     /locus_tag="IT892_001572"
     CDS             complement(13717..14607)
                     /gene="cyoE"
                     /locus_tag="IT892_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HAP3134802.1"
                     /translation="MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
                     ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
                     VMMSVDFMVPDSHTLLAAVW"
     gene            complement(14619..14948)
                     /locus_tag="IT892_001573"
     CDS             complement(14619..14948)
                     /locus_tag="IT892_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="HAP3134803.1"
                     /translation="MSHSTDHSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
                     VILGTILAMAVVQVLVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     gene            complement(14948..15562)
                     /locus_tag="IT892_001574"
     CDS             complement(14948..15562)
                     /locus_tag="IT892_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="HAP3134804.1"
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWL
                     ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     gene            complement(15552..17543)
                     /gene="cyoB"
                     /locus_tag="IT892_001575"
     CDS             complement(15552..17543)
                     /gene="cyoB"
                     /locus_tag="IT892_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="HAP3134805.1"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
                     GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
                     ILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
                     WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
     gene            complement(17565..18512)
                     /gene="cyoA"
                     /locus_tag="IT892_001576"
     CDS             complement(17565..18512)
                     /gene="cyoA"
                     /locus_tag="IT892_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="HAP3134806.1"
                     /translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATPDRAAFDQWVAKAKQSPNTMSDMAAFEKLAAPSEYNQVEYFSNVKPDLFAD
                     VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
     gene            complement(18972..20447)
                     /gene="ampG"
                     /locus_tag="IT892_001577"
     CDS             complement(18972..20447)
                     /gene="ampG"
                     /locus_tag="IT892_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide MFS transporter AmpG"
                     /protein_id="HAP3134807.1"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADKWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
                     SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
                     VPGLILLLVCRQTLEYTRVNDNFISRTAYPAGYAFAMWTLAAGVSLLAVWLLLLTMDA
                     LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
     gene            complement(20491..21069)
                     /locus_tag="IT892_001578"
     CDS             complement(20491..21069)
                     /locus_tag="IT892_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414968.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP3134808.1"
                     /translation="MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVT
                     VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGSNGPVN
                     LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
                     NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
     gene            21374..21691
                     /gene="bolA"
                     /locus_tag="IT892_001579"
     CDS             21374..21691
                     /gene="bolA"
                     /locus_tag="IT892_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414969.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="HAP3134809.1"
                     /translation="MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAG
                     SIA"
     gene            22035..23333
                     /gene="tig"
                     /locus_tag="IT892_001580"
     CDS             22035..23333
                     /gene="tig"
                     /locus_tag="IT892_001580"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAP3134810.1"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
                     FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
                     EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMER
                     ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA"
     gene            23579..24202
                     /gene="clpP"
                     /locus_tag="IT892_001581"
     CDS             23579..24202
                     /gene="clpP"
                     /locus_tag="IT892_001581"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAP3134811.1"
                     /translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     gene            24328..25602
                     /gene="clpX"
                     /locus_tag="IT892_001582"
     CDS             24328..25602
                     /gene="clpX"
                     /locus_tag="IT892_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="HAP3134812.1"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKA
                     KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
     gene            25790..28144
                     /gene="lon"
                     /locus_tag="IT892_001583"
     CDS             25790..28144
                     /gene="lon"
                     /locus_tag="IT892_001583"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HAP3134813.1"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     gene            28353..28625
                     /gene="hupB"
                     /locus_tag="IT892_001584"
     CDS             28353..28625
                     /gene="hupB"
                     /locus_tag="IT892_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="HAP3134814.1"
                     /translation="MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     gene            28817..30688
                     /gene="ppiD"
                     /locus_tag="IT892_001585"
     CDS             28817..30688
                     /gene="ppiD"
                     /locus_tag="IT892_001585"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP3134815.1"
                     /translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
                     VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
                     QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYY
                     EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQT
                     KTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
                     KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDIAAKVKHEKALDAYYALQQKVS
                     DAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPG
                     INSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
                     DLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
                     VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     gene            30839..31210
                     /locus_tag="IT892_001586"
     CDS             30839..31210
                     /locus_tag="IT892_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134816.1"
                     /translation="MKHGIKALLITLSLACAGMSHSALAAASVAKPTAVETKAEAPAA
                     QSKAAVPAKASDEEGTRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
                     LKQVPGMGNSLVERNLAVLTL"
     gene            31304..31702
                     /locus_tag="IT892_001587"
     CDS             31304..31702
                     /locus_tag="IT892_001587"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgC/FadM family acyl-CoA thioesterase"
                     /protein_id="HAP3134817.1"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLENSDSFQWM
                     TAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADA
                     LITFVCIDLKTQKALALEGELREKLEQMVK"
     gene            complement(31754..32449)
                     /gene="queC"
                     /locus_tag="IT892_001588"
     CDS             complement(31754..32449)
                     /gene="queC"
                     /locus_tag="IT892_001588"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HAP3134818.1"
                     /translation="MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEID
                     VARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
                     MWIDKAETWALADYYGKLDLVRNETLTCYNGFKGDGCGHCAACNLRANGLNHYLADKP
                     TVMAAMKQKTGLR"
     gene            complement(32514..34214)
                     /locus_tag="IT892_001589"
     CDS             complement(32514..34214)
                     /locus_tag="IT892_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HAP3134819.1"
                     /translation="MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTLL
                     RQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAMMEQALETGKQQDVLELAQLAPG
                     ELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDN
                     NTQRPIGDLAHHWETSTDGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPALDQ
                     LFISVKRIEVTHPQCLTFFLHRPDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTA
                     ELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQITIGKPEELQRVSQV
                     SSGISLGFCYLTLRKSPRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWT
                     IPHWQVPDEVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTT
                     LQAHADLMMGDRLIGEAPEYTLEQWLRCDPLWPHVFDAPAYAHLQSTLDAVQIMPDEE
                     NRFNALKAVFSQLMTDATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAWLPAPSQ
                     "
     gene            34314..35132
                     /gene="cof"
                     /locus_tag="IT892_001590"
     CDS             34314..35132
                     /gene="cof"
                     /locus_tag="IT892_001590"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HMP-PP phosphatase"
                     /protein_id="HAP3134820.1"
                     /translation="MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGR
                     HALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASM
                     HIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQI
                     QLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDVMNDRE
                     MLVSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE"
     gene            35285..35743
                     /locus_tag="IT892_001591"
     CDS             35285..35743
                     /locus_tag="IT892_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAP3134821.1"
                     /translation="MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLED
                     DGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWYCRFVTVVTEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     gene            35773..37545
                     /locus_tag="IT892_001592"
     CDS             35773..37545
                     /locus_tag="IT892_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HAP3134822.1"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVD
                     GVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQL
                     TLFSLLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSALFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQ
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPVVNDGSEPVPEGRGE
                     LDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGD
                     IRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLAS
                     VHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTE
                     HQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDVLAQQSGWYRD
                     MYRYQQLEAALDDAPENREEAVDA"
     gene            37538..39319
                     /locus_tag="IT892_001593"
     CDS             37538..39319
                     /locus_tag="IT892_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HAP3134823.1"
                     /translation="MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPL
                     LISYFIDNMVAKNNLPLKVVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRT
                     DVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAM
                     FSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSAS
                     GTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDR
                     PLQSGTIEVDNVSFAYRDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP
                     LTEGEIRLDGRPLSSLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQAL
                     ETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASID
                     SGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG
                     RYWQMYQLQLAGEELAASVREEESLSA"
     gene            39500..39838
                     /gene="glnK"
                     /locus_tag="IT892_001594"
     CDS             39500..39838
                     /gene="glnK"
                     /locus_tag="IT892_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAP3134824.1"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRI
                     RTGEADEAAL"
     gene            39868..41154
                     /gene="amtB"
                     /locus_tag="IT892_001595"
     CDS             39868..41154
                     /gene="amtB"
                     /locus_tag="IT892_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter AmtB"
                     /protein_id="HAP3134825.1"
                     /translation="MKIATIKTGLASLAMLPGLVMAAPAVADKADNAFMMICTALVLF
                     MTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINW
                     LMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTL
                     SYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRS
                     KPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVA
                     FIGYKLADLTVGLRVPEEQEREGLDVNSHGENAYNA"
     gene            complement(41203..42063)
                     /gene="tesB"
                     /locus_tag="IT892_001596"
     CDS             complement(41203..42063)
                     /gene="tesB"
                     /locus_tag="IT892_001596"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="HAP3134826.1"
                     /translation="MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPEERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQITQSLAHLLPPVLKDKFICDRPLEV
                     RPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVAST
                     VQEGVMRNHN"
     gene            42281..42853
                     /locus_tag="IT892_001597"
     CDS             42281..42853
                     /locus_tag="IT892_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134827.1"
                     /translation="MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPA
                     IQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLAQKAVRTEGKQSPFSFV
                     LPFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINQGGTKADLTLVPVQQTAVPV
                     QASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     gene            complement(42884..43195)
                     /locus_tag="IT892_001598"
     CDS             complement(42884..43195)
                     /locus_tag="IT892_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HAP3134828.1"
                     /translation="MEKEDSFPQRVWQIVAAIPEGYVTTYGDVAKLAGSPRAARQVGG
                     VLKRLPEGSTLPWHRVVNRHGTISLTGPDLQRQRQALLAEGVMVSGSGQIDLQRYRWN
                     Y"
     gene            43358..43454
                     /gene="ffs"
                     /locus_tag="IT892_001599"
     ncRNA           43358..43454
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IT892_001599"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            43574..43927
                     /locus_tag="IT892_001600"
     CDS             43574..43927
                     /locus_tag="IT892_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1428 domain-containing protein"
                     /protein_id="HAP3134829.1"
                     /translation="MKYVDGFVVAVPADKKDAYREMAAKAAPLFKEFGALRIVECWAS
                     DVPDGKVTDFRMAVKAEENEEVVFSWIEYPSKEVRDAANQKMMSDPRMKEFGESMPFD
                     GKRMIYGGFESIIDE"
     gene            complement(43969..45519)
                     /gene="pdeB"
                     /locus_tag="IT892_001601"
     CDS             complement(43969..45519)
                     /gene="pdeB"
                     /locus_tag="IT892_001601"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeB"
                     /protein_id="HAP3134830.1"
                     /translation="MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTY
                     SSRVAIRANKVATQGKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVAYIDNNV
                     PQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
                     FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILP
                     LPEMNISIITWASTKMLQKGWHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQ
                     DAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPL
                     TLLIIRSVFEDMGDWLRQHPQQHISINLESPVLTSEKIPQLLRDMINHYQVNPRQIAL
                     ELTEREFADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETSKQEEWLRQHGVHYGQGWLYSKALPKEDF
                     LRWAEQHL"
     gene            complement(45683..46153)
                     /locus_tag="IT892_001602"
     CDS             complement(45683..46153)
                     /locus_tag="IT892_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134831.1"
                     /translation="MTEIQRLLTETIESLNTREKRDNKPRFSISFIRKHPGLFIGMYV
                     AFFATLAVMLQSETLSGSVWLLVVLFILLNGFFFFDVYPRYRYEDIDVLDFRVCYNGE
                     WYNTRFVPAALVEAILNSPRVADVHKEQLQKMIVRKGELSFYDIFTLARAESTS"
     gene            complement(46269..46820)
                     /gene="maa"
                     /locus_tag="IT892_001603"
     CDS             complement(46269..46820)
                     /gene="maa"
                     /locus_tag="IT892_001603"
                     /EC_number="2.3.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
                     /protein_id="HAP3134832.1"
                     /translation="MSTEKEKMIAGELYRSADETLSRDRLRARQLIHRYNHSLAEEHT
                     LRQQILADLFGQVTEAYIEPTFRCDYGYNIFLGNNFFANFDCVMLDVCPIRIGDNCML
                     APGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGA
                     VVTKDVPDNVVVGGNPARIIKKL"
     gene            complement(46992..47210)
                     /gene="hha"
                     /locus_tag="IT892_001604"
     CDS             complement(46992..47210)
                     /gene="hha"
                     /locus_tag="IT892_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HAP3134833.1"
                     /translation="MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFY
                     SAADHRLAELTMNKLYDKIPSSVWKFIR"
     gene            complement(47236..47610)
                     /gene="tomB"
                     /locus_tag="IT892_001605"
     CDS             complement(47236..47610)
                     /gene="tomB"
                     /locus_tag="IT892_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity modulator TomB"
                     /protein_id="HAP3134834.1"
                     /translation="MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAI
                     NLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRK
                     SGNRLFRCFVNATKENPASLSC"
BASE COUNT        11895 a        11944 c        12808 g        11325 t
ORIGIN      
        1 tgtgtaatga acgtttcacc acctttgaag tggcggagct ggttatgccg cgtgttgtaa
       61 aaagcaacga cgtgcgtgaa ccgtttaatg aagagaaatt gcgtagcgga atgctgcggg
      121 cgctggaaaa acgtccggtg agttccgatg acgtcgaaat ggcaatcaat catattaaat
      181 cgcagctgcg cgccaccggt gagcgcgaag tgccgagcaa gatgattggc aatctggtga
      241 tggagcaatt gaaaaagctc gataaagtcg cctatatccg ttttgcctct gtctaccgca
      301 gtttcgaaga tatcaaagaa tttggcgaag agatcgcgcg cctggaggac taagccgtgc
      361 aggacgagta ttacatggcg cgggcgctaa agctggcgca acgaggacgt tttaccacgc
      421 atcccaaccc gaatgtcggg tgcgtcattg tcaaagatgg cgaaattgtc ggtgaaggtt
      481 accaccaacg tgcgggtgaa ccacatgccg aagtacacgc gttgcgtatg gcgggtgaaa
      541 aagccaaagg tgcgaccgcc tatgtcacac tcgaaccctg tagccatcat ggtcgtacgc
      601 caccgtgctg tgacgcactc atcgccgctg gcgtagcgcg cgtggttgcc tcgatgcaag
      661 atcctaaccc gcaggtcgct gggcgtggac tttaccgtct gcaacaggct ggcattgacg
      721 tcagccacgg cctgatgatg agtgaagccg agcaattgaa taaaggcttt ctcaagcgga
      781 tgcgcaccgg ctttccttat attcagttaa aacttggcgc atcgcttgat ggtcgcacgg
      841 cgatggcgag cggcgaaagc cagtggatca cttcgcccca ggcgcggcgt gatgtacaac
      901 tactgcgcgc gcaaagtcat gccattttaa ccagcagcgc cacggtgctg gcggatgatc
      961 ctgccttaac ggtgcgttgg tctgaactgg atgaacaaac tcaggcgctc tatccgcaac
     1021 aaaatctccg tcagccgata cgtattgtga ttgatagcca aaatcgcgtg acgccggtac
     1081 atcgcattgt gcagcagccc ggcgaaacct ggttcgcgcg tacgcaggaa gattctcgtg
     1141 agtggccgga aacggtgcgt accttgctga ttccagagca taaaggtcat ctggatctgg
     1201 ttgtactgat gatgcaactg ggtaaacagc aaattaacag catctgggtg gaagcggggc
     1261 caacgctcgc tggcgcattg ctgcaggcgg gtttagtcga tgagctgatt gtctatatcg
     1321 cacctaaact attaggcagc gacgcccgcg gattatgcac gctgccaggg cttgagaaat
     1381 tagccgacgc cccccaattt aaattcaaag agatacgtca tgtaggcccg gatgtttgcc
     1441 tgcatttagt gggtgcatga tctcccggct cgaaagggaa gcagcgcacg aaatattatg
     1501 ctaaaatccg cccccctgcg gggccatact cgaacccgaa ggaagaaaat gaacattatt
     1561 gaagctaacg ttgctacccc ggacgctcgc gtcgccatca ccatcgcgcg tttcaacaac
     1621 tttatcaatg acagcctgct ggaaggtgca attgacgcac tgaaacgtat cggtcaggta
     1681 aaagatgaaa acattaccgt tgtttgggtg cctggtgcct atgagctgcc gctggcggcg
     1741 ggtgcactgg ctaaaaccgg taaatacgac gcggtgattg cgctgggtac ggttattcgt
     1801 ggtggcactg cccactttga atatgtcgct ggtggtgcaa gcaacggcct ggcgcatgtt
     1861 gcccaggaca gcgaaattcc ggttgctttt ggggttctga ccactgaaag cattgaacaa
     1921 gcgatcgaac gtgctggcac caaagctggc aacaaaggtg cagaagctgc actgaccgcg
     1981 cttgaaatga ttaatgtatt gaaagccatc aaggcctgaa attagtaagg ggaaatccgt
     2041 gaaacctgct gctcgtcgcc gcgctcgtga gtgtgccgtc caggcgctct actcctggca
     2101 gttgtcccag aacgacatcg ctgatgttga ataccagttc ctggctgaac aggatgtaaa
     2161 agacgttgac gtcctgtact tccgtgagct gctggccggg gtggcgacta ataccgcata
     2221 cctcgacgga ctgatgaagc catacctgtc ccgcctgctg gaagaactgg gacaggtaga
     2281 aaaagcagta ctgcgcattg cgctgtacga actgtctaaa cgtagcgatg tgccatacaa
     2341 agtggccatt aacgaagcga tcgaactggc gaaatcgttc ggcgcagaag acagccataa
     2401 gttcgtcaac ggcgtactcg ataaagcagc acctgtgatt cgccctaaca aaaagtgata
     2461 tccaggccgg tagattcacg gaagaccgtt ccatgatcgc cggccttttc ttttttacct
     2521 gctgaggcat aacgtatggc atgtggcgag ttctccctga ttgcccgtta ttttgaccgt
     2581 gtaagaagtt ctcgtcttga tgtcgaactg ggcatcggcg acgattgcgc acttctcaat
     2641 atccccgaga aacagaccct ggcgatcagc actgatacgc tggtggcggg taaccatttc
     2701 ctccctgata tcgatcctgc tgatctggct tataaagcac tggcggtgaa cctaagcgat
     2761 ctggcagcga tgggggccga tccggcctgg ctgacgctgg cattaacctt accggacgta
     2821 gacgaagcgt ggcttgagtc cttcagcgac agtttgtttg atcttctcaa ttattacgat
     2881 atgcaactca ttggcggcga taccacgcgt gggccattat caatgacgtt gggtatccac
     2941 ggctttgttc cgatgggacg agccttaacg cgctctgggg cgaaaccggg tgactggatc
     3001 tatgtgaccg gtacaccggg cgatagcgcc gccgggctgg cgattttgca aaaccgtttg
     3061 caggttgccg atgctaaaga tgcggactac ttgatcaaac gtcatctccg tccatcgccg
     3121 cgtattttac aggggcaggc actgcgcgat ctggcaaatt cagccatcga tctctctgac
     3181 ggtttgattt ccgatctcgg gcatatcgtg aaagccagcg actgcggcgc acgtattgac
     3241 ctggcattgc tgccgttttc tgatgcgctt tctcgccatg ttgaaccgga acaggcgctg
     3301 cgctgggcgc tctctggcgg tgaagattac gagttgtgtt tcactgtgcc ggaactgaac
     3361 cgtggcgcgc tggatgtggc tctcggacac ctgggcgtac cgtttacctg tatcgggcaa
     3421 atgaccgccg atatcgaagg gctttgtttt attcgtgacg gcgaacctgt tacattagac
     3481 tggaaaggat atgaccattt tgccacgcca taaagatgtc gcgaaaagtc gcctgaagat
     3541 gagtaatccg tggcatctac ttgctgtcgg attcggaagt ggattaagcc cgatcgttcc
     3601 tgggacgatg ggctcgctgg cagcgattcc gttctggtat ctgatgacct ttttgccctg
     3661 gcagctctac tcgctggtgg tgatgctggg gatctgtatc ggcgtctatc tttgtcatca
     3721 aacggcgaaa gacatgggtg tgcacgatca tggcagcatt gtctgggacg aatttattgg
     3781 tatgtggatc acgctcatgg cgctgccgac caatgactgg cagtgggttg ccgccgggtt
     3841 tgtgattttc cgtattctgg atatgtggaa gccgtggccg atccgctggt ttgatcgcaa
     3901 tgtgcatggc ggcatgggga tcatgatcga cgatattgtc gccggggtga tttccgcagg
     3961 catcctgtat tttatcggtc atcactggcc gctgggtatt ctgtcgtagt tgtgcaccga
     4021 tgcctgatgt gacgcttgtc acgtctcatc aggcctggac tcttatttaa atcctacgac
     4081 aggatgcggt ttatacggcg tttccagttc ggcaatctgt tccggcttca aagtgatatc
     4141 caccgcgttc aatagctcat caagctgttc ttcgcgcgaa gttccgataa tcggtgcggc
     4201 aatgcccggt ttactcaaca accaggccag cgcaacttgt gctcgtgtcg cccccagttc
     4261 ttcactgacg cctgttaacc gctctgcgat ctgcgcgtca ttttcatcgc tttctttata
     4321 gagatttttc cccacctcat cagacaccag tcgtgcggta gtttctcccc acggacgcgt
     4381 cagacggccc cttgccagcg ggctccatgg aattaccgcc acgccctcct gataacacag
     4441 tggtagcatc tcgcgctctt cttcacgata aatcagattg tagtgatcct gcatactgac
     4501 aaactgcgcc cagccgtgct gtttttggag ttccagtgcc tgagcaaact gcgaagcgtg
     4561 cattgatgac gcgccgatat aacgcgcttt cccggctttt accacgtcgt tgagggcttc
     4621 cagcgtctct tcgatcggcg tgttgtaatc ccagcgatga atttgcagga tatcgacata
     4681 atccatgccg agacgtcgca ggctgtcgtc gatagagcgc aaaatttgcg cacgggataa
     4741 tccttccggt aaatcaccaa cgcgatggaa cactttggtc gcaacgacca cgtcttcacg
     4801 acgggcgaaa tcccgcagtg cgcgaccgac gatctcttcg ctgctgccgt cagaataact
     4861 gttggcggta tcaaagaaat ttatgccgcc ttccagtgca cgtttaatta tgggacggct
     4921 gctttcttcc ggcagtgtcc atgcgtgatt accgcgatct ggctcgccaa aggtcataca
     4981 gccgaggcaa agtcgggaaa cgcgaaggtc ggtttttcct aaggggttgt attgcatgct
     5041 gccactcctg ctatactcgt catacttcaa gttgcatgtg ctgcggctgc attcgttcac
     5101 cccagtcact tacttatgta agctcctggg gcttcactcg tttgccgcct tcctgcaact
     5161 cgaattattt agagtctatg aataatttct taagcatagc aggagtggag tagggattat
     5221 gccagccagg ccttgatttt ggcttccata ccagcggcat cgaggccgag ttcggcgcgc
     5281 atttcttcct gagttccttg cggaataaag aagtccggca ggccaatgtt cagcacgggt
     5341 actggtttac gatgggccat cagcacttcg ttcacgccgc tgcctgcgcc gcccataatg
     5401 gcgttttctt ctacggtgac cagcgcttca tggctggcgg ccatttccag aattaacgct
     5461 tcatcaagcg gtttcacaaa acgcatatcg accagcgtgg cgttcagcga ttcggcgact
     5521 ttcgccgctt ctggcatcag cgtaccaaag ttaaggatcg ccagtttctc gccacgacgc
     5581 ttcacaatgc ctttgccaat tggtagtttt tccagcggcg tcagttccac gccgaccgcg
     5641 ttgccacgcg ggtagcgcac cgctgacggg ccatcgttat agtgatagcc ggtatagagc
     5701 atctggcgac attcgttttc atcgctcggg gtcataatga ccatttccgg tatgcagcgc
     5761 aggtaagaga gatcaaaagc accctgatgg gtttgaccgt cagcaccaac aatgcccgcg
     5821 cggtcgatgg cgaacaggac cggaagcttt tgaatcgcca cgtcatgcag cacctgatca
     5881 taggcgcgtt gcaggaaagt ggagtaaatc gcgacaatgg gtttgtaccc accaatcgcc
     5941 agacccgcag caaaggtcac cgcgtgttgc tcggcaattg ccacgtcgaa gtagcgatcc
     6001 gggaatttac gtgaaaactc gaccatgccg gaaccttcac gcatcgccgg agtaatcgcc
     6061 atcagcttgt tgtctttcgc tgccgtttcg cacaaccagt cgccaaagat ttttgaatag
     6121 ctcggcaaac cgccgctact tttcggcaaa caaccgctgg agggatcaaa tttaggcacg
     6181 gcgtggaaag tgatcgggtc tttttctgcc ggttcataac cacgaccttt tttggtcatg
     6241 atatgcagga actgcgggcc tttcaggtcg cgcatgttct ttagcgtggt gataagcccc
     6301 agcacatcgt gaccgtccac cgggccgatg tagttaaagc ccagctcttc aaacaacgtg
     6361 ccaggcacta ccatgccttt aatatgttct tcggtgcgtt tgagcagctc tttaattggc
     6421 ggcacgccag agaaaacttt tttcccgcct tcgcgcagtg aagagtaaag cttaccggaa
     6481 agcagctgtg ccagatggtt gttgagcgcg ccgacatttt cggaaatcga catttcattg
     6541 tcgttgagaa tcaccagcat atcaggacgg atatcgcccg cgtgattcat cgcttcaaac
     6601 gccatgcctg cggtaatcgc gccatcgcca atgacacaga cggtgcggcg atttttgcct
     6661 tctttttcgg cagcaaccgc aataccaatt ccggcactga tggaggttga tgaatgcccg
     6721 acgcttaata cgtcatattc gctttcgccg cgccacggga acgggtgcag accgcctttc
     6781 tgacggatgg tgccgatttt gtcgcggcgt ccggtcaaaa ttttatgcgg ataagcctga
     6841 tgccccacat cccaaatcaa ttggtcaaac ggggtgttgt agacatagtg cagcgccacg
     6901 gtcagttcga ccgtgcccag cccggaggcg aagtgcccgc tggaacggct cacgctgtcg
     6961 agtaaatagc ggcgcagttc gtcgcagagt ttcggtaaac tctctttcgg caacagtcgt
     7021 aactcctggg tggagtcgac cagtgccagg gtcgggtatt tggcaatatc aaaactcatc
     7081 aggggcctat taatacttat tgtttattta ttacgctgga tgatgtagtc cgctagcgct
     7141 tccagtgccg aggtatcgag tgactgttca gccagttgtt tcagcgactg acgggcatcg
     7201 tcgatcagat cccgggcttt cttccgggct tgctcaagac ccagaagtgc agggtaggta
     7261 cttttaccaa gttgctggtc ggcaccctgg cgttttccca acgttgcagt atctcccacc
     7321 acatccagga tgtcatcctg aacctggaag gcaaggccga tgctctctgc atacttgtcg
     7381 agtaccggca gagcacgacg tcctttatct ccggcgctta atgcaccaag gcgaacggcg
     7441 gcgcgaatca atgcgccggt tttatgacga tgaatacgct caagcgcgtc cagaggtacg
     7501 tgtttgcctt ccgcgtctaa atctaatgcc tgaccaccgc acattccggc aataccactg
     7561 gcgctcgcca gttcagaaat catcgaaatt ctgtcgcggt ccgacacttc cggcatatcg
     7621 gcatcgctta aaatcgagaa cgccagcgtt tgtaaagcgt cgccagcgag aatcgcgttt
     7681 gcttcgccaa acttcacatg gcaggttggc aaaccgcgac gcagatcgtc atcatccatt
     7741 gccggtaaat catcatgaat taatgagtaa gcgtggatac actcaacggc ggcagcgggt
     7801 gcgtccagcg tgtttgtgct aacgccgaac atatgaccgg tggcataaac caggaaaggt
     7861 cgcaggcgct taccacctaa taatgcgcca tactgcatgg tttcgaccac gggagtgttc
     7921 tgaaagggca gtggggcgat aaaacggctc agcgcctggt tggcctgctt aacgcaggct
     7981 tcgagttgct gcggaaagtc cattactcat tgtccggtgt aaaaggggtt agagaggcgt
     8041 cttcattgtc agacagcaga atttgtacgc gctgttcggc ttgttgtaat ttggcctgcc
     8101 cctgacgtgc cagctgcacg ccgcgttcga actcgttcag cgcctcttcc agcggcaggt
     8161 cgccactttc cagacgggtt acaatctgtt ccagctcgct cagcgccttt tcaaagctgg
     8221 cgggcgcctc atttttcttc ggcataatga atgtctgact ctcaatattt ttcgccccgt
     8281 catggtaacg gactcagggc aaatagcaaa taacgcgcaa tggtaaggtg atgtgcacag
     8341 caaagcgatg ttagtggtat acttccgcgc ctggatgcag ccgcaggtgt gggctgctgt
     8401 atttttccct atacaagtcg cttaaggctt gccaacgaac cattgccgcc atgaagttta
     8461 tcattaaatt gttcccggaa atcaccatca aaagccaatc tgtgcgcttg cgctttataa
     8521 aaatccttac cgggaacatt cgtaacgttt taaagcacta tgatgagacg ctcgctgtcg
     8581 tccgccactg ggataacatc gaagttcgcg caaaagatga aaaccagcgt ctggctattc
     8641 gcgacgctct gacccgtatt ccgggtatcc accatattct cgaagtcgaa gacgtgccgt
     8701 ttaccgacat gcacgatatt ttcgagaaag cgttggttca gtatcgcgat cagctggaag
     8761 gcaaaacctt ctgcgtacgc gtgaagcgcc gtggcaaaca tgattttagc tcgattgatg
     8821 tggaacgtta cgtcggcggc ggtttaaatc agcatattga atccgcgcgc gtgaagctga
     8881 ccaatccgga tgtgactgtc catctggaag tggaagacga tcgtctcctg ctgattaaag
     8941 gccgctacga aggtattggc ggtttcccga tcggcaccca ggaagatgtg ctgtcgctca
     9001 tttccggtgg tttcgactcc ggtgtttcca gttatatgtt gatgcgtcgc ggctgccgcg
     9061 tgcattactg cttctttaac ctcggcggcg cggcgcatga aattggcgtg cgtcaggtgg
     9121 cgcattatct gtggaaccgc tttggcagct cccaccgcgt gcgttttgtc gctattaatt
     9181 tcgaaccggt cgtcggggaa attctcgaga aaatcgacga cggtcagatg ggcgttatcc
     9241 tcaaacgtat gatggtgcgt gccgcatcta aagtggctga acgttacggc gtacaggcgc
     9301 tggtcaccgg cgaagcgctc ggccaggtgt ccagccagac gctgaccaac ctgcgcctga
     9361 ttgataacgt ctccgacacg ctgatcctgc gtccgctgat ctcttacgac aaagagcaca
     9421 tcatcaacct ggcccgccag attggcaccg aagactttgc tcgcacgatg ccggaatatt
     9481 gtggtgtgat ctccaaaagc ccgacggtga aagcagttaa atcgaagatt gaagcggaag
     9541 aagagaagtt cgacttcagc attctcgata aagtggttga ggaagcgaat aacgttgata
     9601 tccgcgaaat cgcccagcag accgagcagg aagtggtgga agtggaaacc gtcaatggct
     9661 tcggcccgaa cgacgtgatc ctcgatatcc gttctatcga tgaacaggaa gataagccac
     9721 tgaaagtcga agggattgat gtggtttctc tgccgttcta taaactgagc accaaatttg
     9781 gcgatctcga ccagaacaaa acctggctgc tgtggtgtga gcgcggggtg atgagccgtc
     9841 tgcaggcgct ctatctgcgc gagcagggct ttaacaatgt gaaggtatat cgcccgtaat
     9901 ttgtggtttt tacgtcgcat ctggtcagat gcgacgtttg ccgcatccga cactactcgt
     9961 aataattata aatccctgcc gccatcacca gttgtgatgc cacttcatgg gctttttcac
    10021 gcccaaccaa caggtcgata attttcagac caaagtcgat agctgtaccc ggcccctggc
    10081 tggtcagcaa ttttacccgt gcatcccaga cgacgcgctt gtccagccat tgttcggcgg
    10141 gaattttgtc tttcagcgtc gggaagccgg tcatattacc aatcgggaag atatcgtgcg
    10201 gcaccagcac ggtggctggc gcggcgcaaa tagccgcgac gatacgcccg gaacggtgga
    10261 actgtttaac ggtttcaacc agcagagtgc tatcgcgaaa acactccgcg cctttaatgc
    10321 caccaggcag cacgatcacg tcatattcgc catcagccac ttcgaccagc ggcgcatccg
    10381 ccagcagctt cacgtcgcgc gagcaggtaa tcgccaggtt accatcgctg gcgacgctgg
    10441 cagtggtgac tttgataccg ccgcgaacca gcagatcgat agtggtgacg gcttcagtct
    10501 cttcactacc aggggcgagg caaaccagtg ccgatgcgct catattcact ctcctttctt
    10561 tttaccattt caaacaggcg ggtgttttcc ggtacggcaa tcccatgcgc gcgggcgcgg
    10621 cgtaagagaa aaccattgat atagtcgatt tcagtgtggc gcagcgcgcg gatatcctgc
    10681 aacatcgacg agatattttc cgctgtggca tcaatcacct gcatcacgta atcacgcaaa
    10741 tcttctgctg aagtatgatg cccttcgcgt tcgatcaccg ccgcgacttc ttcgcatatc
    10801 tgcataattt cttgcggatg atgacgtaat tcaccgttcg ggcaattcca gatggcagtc
    10861 agtggattaa tcacgcagtt gactgccagc ttgcgccaca gctcggcgcg aatattgtta
    10921 tgccaggcaa cgtcaggcaa cacggtttgc aaaatatccg ccagataact gtaatccccg
    10981 tcctgttgcc gtgccgggcc aatatgcgtg ataccgtttg ccacatgaat aatgacattg
    11041 ccgtcgcggc gggctgcatg ggtggtggtg cccatcagta atggctgctg aatgttttgc
    11101 aactcttcga tggtgcccat gccgttgtga attaacagta ttggcgtagt tacaggcagt
    11161 gtggacgcga ggcttttgac ggcatcggaa acctgccatg ctttcagcgt caccaggagc
    11221 agatcgctgg tggcgagaaa atcgggatcg ttggcggtca gcgattcgtt aaatatcgaa
    11281 ccatctgtct caaccagatt cacgctacaa taaggttgcg gtacgcgcag ccagccctga
    11341 acttcatgac cctgtttgca aagtgctgta agccataatt gccctaaggc accgcatccc
    11401 aatacggtaa ttttcattgt tcctcctcac ccgcaaccac tccgggtgtt caataaggct
    11461 atcccttaat tgtgcatgct gttgcgacta tgcacaatta agggatacgt cctggtgcag
    11521 gactgtcggt tatttaactt tgcgggtatt atgcttcgca tcaaaaatga agggagagga
    11581 aaagatgcca tctttcgata ttgtctctga agttgatctt caggaagcac gtaacgcggt
    11641 cgataacgcg agccgcgaag tggagtcccg ttttgacttc cgtaacgttg aagcctcatt
    11701 tgagctgaac gacgccagca aaaccatcaa agtgttgagc gagtccgatt tccaggtcaa
    11761 tcagttgctg gatattctgc gtgccaagct gctgaagcgc ggcattgaag gcagttcgct
    11821 ggatgtaccg gagaatatcg ttcatagcgg taaaacctgg tttgtggaag cgaaactgaa
    11881 acagggcatt gagagcgcga cccagaagaa aatcgtcaag atgatcaaag acagcaaact
    11941 gaaagtgcag gcgcaaattc agggcgatga aatccgcgta acgggcaaat ctcgtgatga
    12001 tttgcaggct gtcatggcga tggtacgtgg tggcgatctc ggtcagccgt tccagttcaa
    12061 aaacttccgc gattaatcgc gactatgtgc gttttgttca tgtcagatgc ggcatgaacg
    12121 cctgattcgg cctacaaagg tttgtaattc agaaactttg taggcctgat aagcgtagcg
    12181 cagcaggcaa ttcgccgcgt tttttatgcc tgacgaattg cctgttctat ctcaaagcga
    12241 ttcgtcactt tgctgtcgat tttcacataa gctgaatgtt cttcttctgc aatcaacact
    12301 tctttgatgc cttcagtttc tagcaaacgc acttttaacg cctcgtttgc ggcaatgttc
    12361 gccgggattt caatgcgcaa actgctgaca tacggcggtt ctttcatggt actggcgact
    12421 gtcagccaca ctgcggccag cattgcgcca gcgagaaata ccccctgacc gtcaaacatg
    12481 ccgttaatcc agccgcccag cgaaccgcca atcgccacgc caagaaactg gctggtggag
    12541 taaacaccca tcgccgtacc tttgtaacct gctggcgact ctttactgat aagtgagggc
    12601 aagagggctt ccatcaaatt aaacgccaca aagaaaagct gcacgccgac caccagttgc
    12661 cagaactgcg tttgcgcgtt ccacaacaca atttccgcaa ccacgatcaa cccgacgcag
    12721 aagacaaaga cttgcttcat tttgcgctta acttcagcgt agataatgaa aggcacgacc
    12781 gagccaaagg cgattagcat tgtcgccaga tagaccttcc agtgttcagc cgccgggaac
    12841 cctgcatcag ccagttgtcc gggcagggca acaaacgtcg acatcagcaa aatatgcaga
    12901 cacataatgc caaagttgag tttcagcagc cgcggttccg ccagcacttt actgaaactg
    12961 cctttcacca ttccggactc acgattaagt acgtgagtgc tactgttggg cacaacccaa
    13021 atggtcaacg caatgccggt cgttgccaga atagcgatca tccagaacag cgcgtgcagc
    13081 ccaagtttgt gagtgatgat cgggccaagc accatcgcaa tggcaaaggt aatgccaaag
    13141 ctcacgccga taaacgccat cgctttggtg cggttttgtt cgcgcgtgag atcggaaagc
    13201 agcgccataa cggcggcggc aattgctcca gagccttgta gcgcccggcc cagaataatt
    13261 ccccagatgg agtcggaaag cgcagcgata acgctaccgg cggcaaacac cgccagccca
    13321 ccgacaatta atggtttgcg accaatgcgg tcggaaagca ggccaaacgg aatctgaaaa
    13381 acggcctgag tcagaccata aataccaatg gcaataccga ttaatgcttc gctggcacct
    13441 tgcagagcca tgccgtacgt ggtcagaacc ggcagaacca taaacatgcc cagcatgcgc
    13501 aacgagaata cggtccctaa accccaggtc gcgcgcctct cacctggcgt cattttataa
    13561 tcgttcatta ccacctctgt tttaaattcg cgactagtgt aaagcggcaa acgaatgggg
    13621 taaacatgcg gattttttag taaatatttc gagagggata tgtttctaat gctaagaaaa
    13681 aaggtgccgt agcacctttt taatagagag gttttgttac cacacagcag ccagcagcgt
    13741 atgcgagtcc ggtaccataa aatcaacgga catcatcacc gagagggcag tgatggcgat
    13801 gatagagaag ccgaacagct tgcgcgccca gattctgtca tcagcaactt tataaccgcg
    13861 cagagccata cctaaccacc agacgctaac cgccgcggcg accaccagat atttataccc
    13921 agcgtaaccg ccaagagaga gcatcagcgt ggcaacggca aaggcgatga tatacagcgt
    13981 gatgtgattc ttcgccaccg aaatgccttt taccactggc aataccggaa tgtttgccgc
    14041 ctggtaatcc ttaaagcgga aaatggcgat ggcataggag tgaggcatct gccacaggct
    14101 gaagatagcc agcaggatcg ctgcgccgct atcgaactca ccggttaccg cacagtagcc
    14161 gatcaccggc ggcgcagcgc cggagagcga accaatcaac gtgccgtaga cagagtggcg
    14221 tttcatgtac aggctataaa cgccgacata aaccacaaag cccatcaccc ccagccagca
    14281 ggccagcgga ttcgcgccaa accacagcag cataaagcca gcaataccca gcaacgtggc
    14341 gtacaccagc gagacagcag gagagatcag gcctttcacc agcacccgat tcttcgtcct
    14401 ttccatcttt ctgtcgatat ccctgtcgat gtagttgtta aacacacaac ccgacgccac
    14461 aaccagtgac accccaacca gcgtgtagat aaacagggga taatcaatgc tgccctttga
    14521 ggccagcagg aatcccccaa tcaccgagat caggttgcca aagatgatgc ctggtttcgt
    14581 tacttgcagg tattgcttaa acatcataac cgccgctctt agtgcatcat catgttgtag
    14641 ttgaggttcc acataatcca gatggagcct acaaccagga tagcgatgat tagcacggtg
    14701 aagacaaacg ccgtcatgtt ccagccttca tctgatttgg tattcatgtg caggaagcac
    14761 accagatgca ccagaacctg taccactgcc attgccagga ttgttcccag aattacggcc
    14821 ggagaggcag ctcctgtcat caccatccag aacggaatca ccgtcagaat gatcgacagg
    14881 ataaagcctg tcatgtaggt ttttacgctg ccatgggacg cgccgctgtg atcggtagaa
    14941 tgactcatta catcgccccc atcagataaa caacagtgaa cacacagatc caaaccacat
    15001 ccaggaagtg ccagaacagg ctcaggcaca tgatgcgggt acggttagtg ctggtcaggc
    15061 cgcgacgggc gatttgcacc atcagcaccg ccatccagat aagaccagaa gtgacgtgca
    15121 gaccgtgcgt gccgaccagc gcaaagaacg ctgacaggaa gccgctgcga tccggaccca
    15181 tgccgttaac aatcaggtga tggaattcat agatttccat cccgataaat ccggcaccaa
    15241 acaaccaggt caacgccagc caggagataa cctggctttt gttgtttttg tacatggcga
    15301 tagccgccat gccgtaggtg atggagctga acaacagcaa gaaagtttca accagaacga
    15361 acggcagttc gaaaatgtcc ttacctgtcg ggccgcctgc ggtgccgttc accagaacgg
    15421 cataggtagc aaacaagata gagaacagaa tgcagtcgct catcaggtag atccaaaatc
    15481 cgaagatttt ggttccgcct gcatcgtggt gcccgtgttc gtgcgcgtgg gcagtcgcgt
    15541 gcgtcaaagt atcagttgcc atttttcagc cctgccttag taatctcatc gaaatgctgg
    15601 ttttccagtt tttcgatttc tgccaccggc acgtagtaat ccacgtcctc gtcgaagctt
    15661 ttcacgatcc aggtgatgat catgcctgcg aagccaacaa tcgccagcca ccagatatgc
    15721 cagatcatgg cgaaaccgaa gatggtggag aaagctgcaa tgacgatacc tgcaccgctg
    15781 tttttcggca tatgaatttc ttcatagtgg tcaggctttt tatacgcttc gcctttctct
    15841 ttcatttccc agaatgcatc acgttcgtga acgtgcggca ctacggcaaa gttatagaac
    15901 ggaggcgggg aagaggttgc ccactccagc gtacggccac cccacgggtc gccagtcagg
    15961 tcacggttct ggtcgcggtc gcgaatagaa acgtacatct gaataacgag gcagagaata
    16021 cccagcgcaa tcagtactgc accgctggct gcaatcatca gcatggtgtg gaactgcggg
    16081 tcaatctgct ggctcaaacg acgggtcatg cccatgaagc ccagcgcata cagtggcata
    16141 aaggcaacga agaagccgat gatccagaac cagaacgcgc gtttacccca ggtttcgttc
    16201 agtttgaaac cgaacgcttt aggccaccag taggtcatcc ctgcgaagca gccgaagacc
    16261 acgccgccga tgatcacgtt atggaagtgc gcaatcagga acaggctgtt atgcagaacg
    16321 aagtccgcgc ccggtacggc cagcagcacg ccagtcatcc cgcccaccga gaaggtgacg
    16381 ataaaaccga tggtccacag catcgcagaa tggaacacga tgcggccctg atacatggtg
    16441 aacagccagt tgaagatctt caccccggtc gggatggcga taatcattgt ggtgatacca
    16501 aagaaggcgt ttacgttcgc gcccgcaccc atcgtaaaga agtggtgcag ccaaacgatg
    16561 aacgacagca cggtgataca gacggttgcc cataccagcg aggtataacc aaacagacgt
    16621 ttacgcgaga aggttgccgc aatttcggag aacacaccga aaacaggcag gatcaggatg
    16681 taaacttccg ggtggcccca ggcccaaatc aggttgatgt acatcatcat gttgccaccc
    16741 atatcgttgg taaagaaatg ggtgcccaga tagcgatcca gggtcaacaa cgcgacggta
    16801 accgtcagaa ttgggaagga agcaataatc agtacgttcg cgcacagtga tgcccaggta
    16861 aatactggca tcttgaacat ggtcatgccc ggtgcgcgca tcttcagaat ggtaacgaag
    16921 aagttgatac cggtaagcgt cgtacctata ccggatagct ggagactcca tatccagtaa
    16981 tcgacaccga ctcccggact gtactctatt cccgatagcg gtggataggc cagccagccg
    17041 gtctgcgcaa attcgcccac gccgagagaa acgttaacca gaatcacacc aacaacggta
    17101 aaccagaagc ttaagttgtt gaggaacggg aacgcaacgt cacgcgcgcc gatctgcagc
    17161 ggaaccacca ggttcatcag accgataacg aaaggcatcg ccacgaagaa gatcataatc
    17221 acgccgtgcg cggtaaagat ctgatcgtag tggtgaggtg gcaggaagcc cgcttcgccc
    17281 gccgaggcaa gagcctgctg gctacgcatc ataatggcgt cagcaaaacc acgcagcaac
    17341 atcacaatcg ccacgatgat atacatgata ccgaggcgtt tatggtcgac ggaggtcagc
    17401 cactctttcc acaggtaggt ccacttaccg aagtaagtga tcaggccaac gagcgccaga
    17461 cctcccaaaa taatgccagc gatcgtaacc atgacgatag gttcatggaa cgggactgca
    17521 tcaagtgata attttccgaa catctttatt cttcctcaac ccctttaatg ggcggattcc
    17581 gcgtggctca tgtccatgcc ttccatacct tcgtgtgcgc tgtgctcacc ttctggctgg
    17641 gtcatgtcca tgctcttacc gtgagccata aacttgttaa ttacatcggc aaacaagtct
    17701 ggtttcacgt tggagaaata ttccacctgg ttgtattcgc taggcgcggc cagtttttcg
    17761 aacgcagcca tgtcagacat ggtgttcggc gactgcttcg cttttgcgac ccactggtcg
    17821 aatgcggcgc gatccggtgt tgcaatagct ttgaacttca tgcctgagaa gcccgggccg
    17881 ctgtagctgg cggagatacc gtcataagtg ccgggttcgt tggcgatcag atgcaggcga
    17941 gtctgcatac cggccatggc ataaatctgg ctacccagac gcggaatgaa gaaggagttc
    18001 atcacggagt tggaggtcac tttgaagtac accggagtgt tcgccgggaa agcgatttca
    18061 ttcacggtag caatgccctg ttccgggtag atgaagaacc atttccagtc catggaaacc
    18121 acttcgatgg taatgggctt ctcgtcgtgt gccagcggct tgctaggctc aagagcgtga
    18181 gtggttttcc aggtcagtac tgcaaggaag atgatgatta agataggtac cgtccagacc
    18241 acagcttcca ctttattgga gtgtgaccag ttcgggctgt acttagcatc tttattgctc
    18301 gcacggtact tccaggcgaa accaacagcc atcaagattg cgggaataac gacaatcaac
    18361 atcaggccaa atgccgtcag tatcagtgaa cgttgctcca gaccaatctg tcctttggga
    18421 tctaacagcg cagaattaca gccactgagc aatacagtgc ctgcaaataa tgacaaccat
    18481 cccaaacttt tattgtattt cctgagtctc atttaacgac ctcaattcca cgggatctgg
    18541 tggcgtttaa agtgtgtggg cattttacgg gaaggttaca ttactgtaaa catgattaaa
    18601 ttcctgttac ttggatttgg ctgccaggtc acatatgttg caaaacatat caggttgatt
    18661 ttaagaagct gttgcaaaag ggcgttataa caaaagggga gtgctgaagg agtctgggcg
    18721 ggcaattggt ataaccaatg tgaaataaaa caattattta acaaataatt atcattagag
    18781 tgacaactgg gtgatgagaa aataaagact cattagctga atcgtgtaag aaaaatagaa
    18841 tttataaatg gcgccaataa tttccaaacg ctaagccgca caaaagaaca aatattaata
    18901 agcgatactg atgtttattt agccgtaata attacggcga gtgattacta cagctaaata
    18961 atatttacag attacgtcag atgcgttttt cgtagcgcca gataatccag caaaccacca
    19021 agcacgacgc cagaaagggc gactaaaacc ccgacttcca gcagagcagg caggaaagag
    19081 aagtgcgtca aatccagcgc gtccatcgtc aatagcagta accacacggc caacaggctg
    19141 acgcccgccg ccagtgtcca catggcaaag gcataacctg ccggatatgc ggtacgggag
    19201 ataaagttgt catttactcg tgtatattca agcgtctggc ggcaaaccag cagcaaaata
    19261 agccctggta cggcagcggc gacggagaat agatagaatg tcgaccagcc gtgtgcttca
    19321 acaaaccaac ccgccacggg gccgacataa actcgcccta cagcagaaag cgctgagagc
    19381 agggcaaatt gagtagcgga aaatgactta ttacatagcg tcattaacag cgcgacaaag
    19441 gctgatgtgc ccatcccgcc acagaggttt tcgaaaaaga cggctgcgcc catgctgtag
    19501 agatgcttat cagtaatcga cagcagccag taaccggcgt tagacgcacc ttgtaaaatg
    19561 ccgaaaatca gcagtgcccg gaacagtgac aggcgctgca tcaaaatccc accgtacaat
    19621 gcgccaacaa tggtcgctag taagccaagc gttttgttaa ccacgcctac ttcacccgca
    19681 tcaaacccga cgccgcgaat caaaaacgtg gttgtcaggc tcatggcgaa tgcgtcgccc
    19741 agcttataca gcacgataag aagcaaaata agccaggcat tattgcgacc aaagaaatct
    19801 cgcagaggtg caacaaccgc ttgttccagc gttttgggca caggaatggt gtcggttggt
    19861 tctggtgcaa gcaacgtcgc gataatacag gggatcaaca gtgccgccat taaccagtac
    19921 atgccctgcc agcccagcca tttatctgcc agccacaggg ctaggccgcc ggaaaccagc
    19981 atccctaaac ggtaacccag cacgctgatt gccgcgcccg caccacgttc ttctgccgga
    20041 agcacatcgg ttttccacgc atcgaagact atatcctggg aagcagagca aaaagcgatc
    20101 accactgcca gcgccgccat ccagcggagt tgggtgcctg gttcgagaaa acccatcgcc
    20161 gcaatggcga ctaataacag gatttgcgtg gcgagcagcc aaccgcgccg ccgcccaaaa
    20221 aatggaggcg tgtagcggtc catcagcggt gaccagagga atttaaaaac gtaagcctgg
    20281 cctaccagag agaagaaacc aatggttttg agatcgatat tctcgaccgt catccaggcc
    20341 tgtaaggtac cggatgtcag ggcgagcggt agcccggaag caaaacccag gatcagcaat
    20401 atggctgaac gcggctgttg aaaaatacgt aaatattgac tggacatggg cgtctacagg
    20461 cccggcttgc accgggccag agggcagaaa ttaacgcgcg ttctgcttga tgaattcgtg
    20521 gatgctggtg tcctgagaca tatcagcgat ggtatcggtc agcacactgt taaccgcatc
    20581 ggcgatattt ttgttggagg cctggaacgc accttcaacg ttgtagctgg cacgatagtt
    20641 tttggtcatt ttgttgccat tctgcgcggt agcgatgatg gcgatatccg ctttggtcgc
    20701 gatgttgtag cgcacgttgc cctgggacac gtcagcatac agttggctaa cgatgatttg
    20761 cagattaacc gggccattcg aaccaaccat gtaaccacgc gcggtcatct gtttttccag
    20821 cacttcttgc agcaggaaac gcagatcgcg ggaggcggtc agggtaacga tttgattatc
    20881 gcgggtgact tttgccagcg cctgatcggt acgctgatcg gcaccattaa tgcttacggt
    20941 gacgcccatc aggcttggat cctgctgtgg cagtgtaatc gtcggggaaa cttcaatagt
    21001 tgttggcggt tttgcgcatc ctgcaagcat aaacagagca actaacggga agaggatttt
    21061 tttgaacatg ttcgggctct cagagactct taagcgtgtt tggtaaaaat tcccgccatc
    21121 ataacattgc caacggcgag gggaagtggg taaggcatgt aaattcatca tgttgacgaa
    21181 ataatcgccc ctggtaaaag aaacactgat gcgaggcctg tgtttcaatc tttaaatcag
    21241 taaacttcat acgcttgacg gaaaaaccag gacgaaacct aaatatttgt tgttaagctg
    21301 caatggaaac ggtaaaagcg gctagtattt aaagggatgg atgacatctc agcgttgtcg
    21361 gaggagatat ttcatgatga tacgtgagcg gatagaagaa aaattaaggg cggcgttcca
    21421 acccgtattc ctcgaagtag tggatgaaag ctatcgtcac aatgtcccag ccggctctga
    21481 aagccatttt aaagttgtgc tggtcagcga tcgttttacg ggtgaacgtt ttctgaatcg
    21541 tcatcgaatg atttacagta ctttagcgga ggaactctct actaccgttc atgcgctggc
    21601 tctgcatact tacactatta aggagtggga agggttgcag gacaccgtct ttgcctctcc
    21661 tccctgtcgt ggagcaggaa gcatcgcgta aaaacgcatt tgcaactgtc ggcgcttttc
    21721 cagtatgttg ctaaagattt tatgaaaaac ggcctgcggg ccgttttgtt ttgtctggat
    21781 tttgcgcttt ttgcccagca ttcagacgaa aattgcccgg gaattgtgaa aaaatacgcg
    21841 acagcgcgca ataaccgttc tcgactcata aaagtgatgc cgctataatg ccgcgtccta
    21901 tttgaatgct ttcgggatga ttctggtaac agggaatgtg attgattata agaacatccc
    21961 ggttccgcga agccaacaac ctgtgcttgc ggggtaagag ttgaccgagc actgtgattt
    22021 tttgaggtaa caagatgcaa gtttcagttg aaaccactca aggccttggc cgccgtgtaa
    22081 cgattactat cgctgctgac agcatcgaga ccgctgttaa aagcgagctg gtcaacgttg
    22141 cgaaaaaagt acgtattgac ggcttccgca aaggcaaagt gccaatgaat atcgttgctc
    22201 agcgttatgg cgcgtctgta cgccaggacg ttctgggtga cctgatgagc cgtaacttca
    22261 ttgacgccat cattaaagaa aaaatcaatc cggctggcgc accgacttat gttccgggcg
    22321 aatacaagct gggtgaagac ttcacttact ctgtagagtt tgaagtttat ccggaagttg
    22381 aactgcaggg tctggaagcg atcgaagttg aaaaaccgat cgttgaagtg accgacgctg
    22441 acgttgacgg catgctggat actctgcgta aacagcaggc gacctggaaa gaaaaagacg
    22501 gcgctgttga agcagaagac cgcgtaacca tcgacttcac cggttctgta gacggcgaag
    22561 agttcgaagg cggtaaagcg tctgatttcg tactggcgat gggccagggt cgtatgatcc
    22621 cgggctttga agacggtatc aaaggccaca aagctggcga agagttcacc atcgacgtga
    22681 ccttcccgga agaataccac gcagaaaacc tgaaaggtaa agcagcgaaa ttcgctatca
    22741 acctgaagaa agttgaagag cgtgaactgc cggaactgac tgcagaattc atcaaacgtt
    22801 tcggcgttga agatggttcc gtagaaggtc tgcgcgctga agtgcgtaaa aacatggagc
    22861 gcgagctgaa gagcgccatc cgtaaccgcg ttaagtctca ggcgatcgaa ggtctggtaa
    22921 aagctaacga catcgacgta ccggctgcgc tgatcgacag cgaaatcgac gttctgcgtc
    22981 gccaggctgc acagcgtttc ggtggcaacg aaaaacaagc tctggaactg ccgcgcgaac
    23041 tgttcgaaga acaggctaaa cgccgcgtag ttgttggcct gctgctgggc gaagttatcc
    23101 gcaccaacga gctgaaagct gacgaagagc gcgtgaaagg cctgatcgaa gagatggctt
    23161 ctgcgtacga agatccgaaa gaagttatcg agttctacag caaaaacaaa gaactgatgg
    23221 acaacatgcg caatgttgct ctggaagaac aggctgttga agctgtactg gcgaaagcga
    23281 aagtgactga aaaagaaacc actttcaacg agctgatgaa ccagcaggcg taatttacgc
    23341 agcataacgc gctaaattcg cacaaaggcc cgtcaccgcc aggtggtggg cttttttttg
    23401 tcatgaattt tgcatggaac cgtgcgaaaa gcctctttcg gtgttagcgt aacaacaaaa
    23461 gattgttatg cttgaaatat ggtgatgccg tacccataac acagggacta gctgataatc
    23521 cgtccataag gttacaatcg gtacagcagg ttttttcaat tttatccagg agacggaaat
    23581 gtcatacagc ggcgaacgag ataactttgc accccatatg gcgctggtgc cgatggtcat
    23641 tgaacagacc tcacgcggtg agcgctcttt tgatatctat tctcgtctac ttaaggaacg
    23701 cgtcattttt ctgactggcc aggttgaaga ccacatggct aacctgattg tggcgcagat
    23761 gctgttcctg gaagcggaaa acccagaaaa agatatctat ctgtacatta actccccagg
    23821 cggggtgatc actgccggga tgtctatcta tgacaccatg cagtttatca agcctgatgt
    23881 cagcaccatc tgtatgggcc aggcggcctc gatgggcgct ttcttgctga ccgcaggggc
    23941 aaaaggtaaa cgtttttgcc tgccgaattc gcgcgtgatg attcaccaac cgttgggcgg
    24001 ctaccagggc caggcgaccg atatcgaaat tcatgcccgt gaaattctga aagttaaagg
    24061 gcgcatgaat gaacttatgg cgcttcatac gggtcaatca ttagaacaga ttgaacgtga
    24121 taccgagcgc gatcgcttcc tttccgcccc tgaagcggtg gaatacggtc tggtcgattc
    24181 gattctgacc catcgtaatt gatgccagag gcgcaactgt gccgctatac ttatccaggg
    24241 cggcacaacg ctgtaagcgg cttgcgcctg agaatggcat ttgcgtcgtc gtgtgcggca
    24301 caaagaacaa agaagaggtt ttgacccatg acagataaac gcaaagatgg ctcaggcaaa
    24361 ttgctgtatt gctctttttg cggcaaaagc cagcatgaag tgcgcaagct gattgccggt
    24421 ccatccgtgt atatctgcga cgaatgtgtt gatttatgta acgacatcat tcgcgaagag
    24481 attaaagaag ttgcaccgca tcgtgaacgc agtgcgctac cgacgccgca tgaaattcgc
    24541 aaccacctgg acgattacgt tatcggccag gaacaggcga aaaaagtgct ggcggtcgcg
    24601 gtatacaacc attacaaacg tctgcgcaac ggcgatacca gcaatggcgt cgagttgggc
    24661 aaaagtaaca ttctgctgat cggtccgacc ggttccggta aaacgctgct ggctgaaacg
    24721 ctggcgcgcc tgctggatgt tccgttcacc atggccgacg cgactacact gaccgaagcc
    24781 ggttatgtgg gtgaagacgt tgaaaacatc attcagaagc tgttgcagaa atgcgactac
    24841 gatgtccaga aagcacagcg tggtattgtc tacatcgatg aaatcgacaa gatttctcgt
    24901 aagtcagaca acccgtccat tacccgagac gtttccggtg aaggcgtaca gcaggcactg
    24961 ttgaaactga tcgaaggtac ggtagctgct gttccaccgc aaggtgggcg taaacatccg
    25021 cagcaggaat tcttgcaggt tgatacctct aagatcctgt ttatttgtgg cggtgcgttt
    25081 gccggtctgg ataaagtgat ttcccaccgt gtagaaaccg gctccggcat tggttttggc
    25141 gcgacggtaa aagcgaagtc cgacaaagca agcgaaggcg agctgctggc gcaggttgaa
    25201 ccggaagatc tgatcaagtt tggtcttatc cctgagttta ttggtcgtct gccggttgtc
    25261 gcaacgttga atgaactgag cgaagaagct ctgattcaga tcctcaaaga gccgaaaaac
    25321 gccctgacca agcagtatca ggcgctgttt aatctggaag gcgtggatct ggaattccgt
    25381 gacgaggcgc tggatgctat cgctaagaaa gcgatggcgc gtaaaaccgg tgcccgtggc
    25441 ctgcgttcca tcgtagaagc cgcactgctc gataccatgt acgatctgcc gtccatggaa
    25501 gacgtcgaaa aagtggttat cgacgagtcg gtaattgatg gtcaaagcaa accgttgctg
    25561 atttatggca agccggaagc gcaacaggca tctggtgaat aattaaccat tcccatacaa
    25621 ttagttaacc aaaaaggggg gattttatct cccctttaat ttttcctcta ttctcggcgt
    25681 tgaatgtggg ggaaacatcc ccatatactg acgtacatgt taatagatgg cgtgaagcac
    25741 agtcgtgtca tctgattacc tggcggaaat taaactaaga gagagctcta tgaatcctga
    25801 gcgttctgaa cgcattgaaa tccccgtatt gccgctgcgc gatgtggtgg tttatccgca
    25861 catggtcatc cccttatttg tcgggcggga aaaatctatc cgttgtctgg aagcggcgat
    25921 ggaccatgat aaaaaaatta tgctggtcgc gcagaaagaa gcttcaacgg atgagccggg
    25981 tgtaaacgat cttttcaccg tcgggaccgt ggcctctata ttgcagatgc tgaaactgcc
    26041 tgacggcacc gtcaaagtgc tggtcgaggg gttacagcgc gcgcgtattt ctgcgctctc
    26101 tgacaatggc gaacactttt ctgcgaaggc ggagtatctg gagtcgccga ccattgatga
    26161 gcgggaacag gaagtgctgg tgcgtactgc aatcagccag ttcgaaggct acatcaagct
    26221 gaacaaaaaa atcccaccag aagtgctgac gtcgctgaat agcatcgacg atccggcgcg
    26281 tctggcggat accattgctg cacatatgcc gctgaaactg gctgacaaac agtctgttct
    26341 ggagatgtcc gacgttaacg aacgtctgga atatctgatg gcaatgatgg aatcggaaat
    26401 cgatctgctg caggttgaga aacgcattcg caaccgcgtt aaaaagcaga tggagaaatc
    26461 ccagcgtgag tactatctga acgagcaaat gaaagctatt cagaaagaac tcggtgaaat
    26521 ggacgacgcg ccggacgaaa acgaagccct gaagcgcaaa atcgacgcgg cgaagatgcc
    26581 gaaagaggca aaagagaaag cggaagcaga gttgcagaag ctgaaaatga tgtctccgat
    26641 gtcggcagaa gcgaccgtag tgcgtggtta tatcgactgg atggtacagg tgccgtggaa
    26701 tgcgcgtagc aaggtcaaaa aagacctgcg tcaggcgcag gaaatccttg ataccgacca
    26761 ttatggtctg gagcgcgtga aagatcgaat ccttgagtat cttgcggttc aaagccgtgt
    26821 caacaaaatc aagggaccga tcctctgcct ggtagggccg ccgggggtag gtaaaacctc
    26881 tcttggtcag tccattgcca aagccaccgg gcgtaaatat gtccgtatgg cgctgggcgg
    26941 cgtgcgtgat gaagcggaaa tccgtggtca ccgccgtact tacatcggtt ctatgccggg
    27001 taaactgatc cagaaaatgg cgaaagtggg cgtgaaaaac ccgctgttcc tgctcgatga
    27061 gatcgacaaa atgtcttctg acatgcgtgg cgatccggcc tctgcactgc ttgaagtgct
    27121 ggatccagag cagaacgtag cgttcagcga ccactacctg gaagtggatt acgatctcag
    27181 cgacgtgatg tttgtcgcga cgtcgaactc catgaacatt ccggcaccgc tgctggatcg
    27241 tatggaagtg attcgcctct ccggttatac cgaagatgaa aaactgaaca tcgccaaacg
    27301 tcacctgctg ccgaagcaga ttgaacgtaa tgcactgaaa aaaggtgagc tgaccgtcga
    27361 cgatagcgcc attatcggca ttattcgtta ctacacccgt gaggcgggcg tgcgtggtct
    27421 ggagcgtgaa atctccaaac tgtgtcgcaa agcggttaag cagttactgc tcgataagtc
    27481 attaaaacat atcgaaatta acggcgataa cctgcatgac tatctcggtg ttcagcgttt
    27541 cgactatggt cgcgcggata acgaaaaccg tgtcggtcag gtaaccggtc tggcgtggac
    27601 ggaagtgggc ggtgacttgc tgaccattga aaccgcatgt gttccgggta aaggcaaact
    27661 gacctatacc ggttcgctcg gcgaagtgat gcaggagtcc attcaggcgg cgttaacggt
    27721 ggttcgtgcg cgtgcggaaa aactggggat caaccctgat ttttacgaaa aacgtgacat
    27781 ccacgtccac gtaccggaag gtgcgacgcc gaaagatggt ccgagtgccg gtattgctat
    27841 gtgcaccgcg ctggtttctt gcctgaccgg taacccggtt cgtgccgatg tggcaatgac
    27901 cggtgagatc actctgcgtg gtcaggtact gccgatcggt ggtttgaaag aaaaactcct
    27961 ggcagcgcat cgcggcggga ttaaaacagt gctaattccg ttcgaaaata aacgcgatct
    28021 ggaagagatt cctgacaacg taattgccga tctggacatt catcctgtga agcgcattga
    28081 ggaagttctg actctggcgc tgcaaaatga accgtctggt atgcaggttg tgactgcaaa
    28141 atagtgacct cgcgcaaaat gcactaataa aaacagggct ggcaggctaa ttcgggcttg
    28201 ccagcctttt tttgtctcgc taagttagat ggcggatcgg gcttgccctt attaaggggt
    28261 gttgtaaggg gatggctggc ctgatataac tgctgcgcgt tcgtaccttg aaggattcaa
    28321 gtgcgatata aattataaag aggaagagaa gagtgaataa atctcaattg atcgacaaga
    28381 ttgctgcagg ggctgatatc tctaaagctg cggctggccg tgcgttagat gctattattg
    28441 cttccgtaac tgaatctctg aaagaagggg atgatgtagc actggtaggt tttggtactt
    28501 ttgccgttaa agagcgtgct gcccgtactg gccgcaaccc gcagaccggt aaagagatca
    28561 ccatcgctgc tgctaaagta ccgagcttcc gtgcaggtaa agcactgaaa gacgcggtaa
    28621 actaagcgtt gtccccagtg gggatgtgac gaagttcaag ggcgcatcta ctgatgtgcc
    28681 ttttttattt gtattcggtg actttctgcg tcttgtgggc tgacaattgc ccccgtttct
    28741 tgtcacaata ggcctttgcg cgcatcgata cgttgcgtga ggtacacagt catctacagc
    28801 ggagtgttgt tacaccatga tggacagctt acgcacggct gcaaacagtc tcgtgctcaa
    28861 gattattttc ggtatcatta tcgtgtcgtt catattgacc ggcgtgagtg gttacctgat
    28921 tggcggaggc aataactacg ccgcaaaagt gaatgaccag gaaatcagcc gtgggcaatt
    28981 cgagaacgcc ttcaacagcg agcgtaatcg catgcagcaa cagctgggcg atcaatactc
    29041 cgagctggca gcgaacgaag gctatatgaa aaccctgcgt caacaggtgc tgaatcgtct
    29101 gatcgacgag gcgctgctgg atcagtacgc acgtgagctg aaactgggta tcagcgatga
    29161 gcaggttaaa caggcgattt tcgcgacccc agccttccag gttgacggca aatttgataa
    29221 cagccgctat aacggtatcc tcaaccagat ggggatgacc gccgatcagt acgcccaggc
    29281 gctgcgtaac cagctcacta cccaacagct gattaacggc gttgccggta ccgattttat
    29341 gctgaaaggt gaaaccgacg agctggcggc actggtcgcg caacaacgcg tggtgcgtga
    29401 ggcgactatc gatgttaacg cgctggcggc gaagcagcct gtgaccgaac aggagattgc
    29461 cagctactac gaacaaaaca aaaacaattt catgacgccg gaacaattcc gcgtgagtta
    29521 catcaagctg gatgccgcaa cgatgcagca accggttagc gatgcggata tccagagcta
    29581 ctacgaccag catcaggatc aattcaccca gccgcagcgt acccgctaca gcatcatcca
    29641 gaccaaaact gaagatgaag cgaaagcggt acttgatgag ctgaataaag gcggtgattt
    29701 tgctgcatta gccaaagaaa aatctgccga tattatctct gctcgtaacg gcggcgatat
    29761 gggttggtta gaagatgcca ctatcccgga cgaactgaaa aatgctggtc tgaaagaaaa
    29821 aggccaactg tctggtgtca tcaaatcttc ggtcggtttc ctgattgtac gtctggacga
    29881 cattcagcca gcgaaagtga aatcgttaga cgaagtacgt gacgacattg cggcgaaagt
    29941 gaaacacgaa aaagccctcg atgcgtacta cgcgctgcag cagaaagtga gcgatgcggc
    30001 aagcaacgac accgagtctc tggccggtgc agagcaagct gccggcgtta aagccactca
    30061 gacgggttgg ttcagcaaag ataacctgcc ggaagagttg aacttcaagc cggttgccga
    30121 cgctatcttt aacggcggtc tggtaggtga aaacggcgcg ccgggcatca actctgacat
    30181 catcaccgta gacggcgacc gcgcattcgt gctgcgcatc agcgagcaca aaccggaagc
    30241 ggtgaaaccg ttggcagatg ttcaggaaca agttaaggca ttggttcagc acaacaaagc
    30301 tgaacaacag gcgaaagtgg atgctgagaa actgctggtt gatttgaaag ccggcaaagg
    30361 tgcggaagct atgcaggctg ccggtctgaa atttggcgag ccgaaaacct taagccgttc
    30421 cggtcgtgac ccgattagcc aggcggcgtt tgcactgcca ctgccagcga aagacaaacc
    30481 gagctacggt atggcgaccg atatgcaagg taatgtggtt ctgctggcgc tggatgaagt
    30541 gaaacaaggt tcaatgccgg aagatcagaa aaaagcgatg gtgcagggta tcacccagaa
    30601 caacgcacaa atcgtctttg aagctctgat gagtaacctg cgtaaagagg cgaaaatcaa
    30661 aattggcgat gcgctggaac agcaataatc ctgaagccgc ctcgcaaaaa aatgcgttgc
    30721 agctgtaaca agaaaaggtc gctttcgcgg ccttttccat ttctgaacat tgccatttgt
    30781 ttactgtttt cactgccgtt aaggtgattc cactgttaac aaacaaggag aaaacagtat
    30841 gaaacacgga attaaagcac tgctcattac cctgtccctg gcctgtgccg gaatgtctca
    30901 tagcgcgctg gcggcagctt ctgtggcgaa accgacggcg gtagaaacca aagcggaagc
    30961 tcctgcagca caaagtaaag cagcagtacc ggcgaaagcc agtgacgaag aaggcacccg
    31021 ggtcagcatt aataatgcca gcgcggaaga gctagcccgc gcgatgaatg gcgttggcct
    31081 gaagaaagcg caggcgattg tcagttatcg cgaagagtac ggtccgttta aaactgtgga
    31141 ggatctaaag caggtgccgg ggatgggcaa ttcgctggtg gaacgtaatc tggcggtatt
    31201 aaccctgtaa ttaatttgca tagtggcaat tttttgccag actgaagagg tcataccagt
    31261 tatgacctct gtacttataa caacaacgta aggttattgc gctatgcaaa cacaaatcaa
    31321 agttcgtgga tatcatctcg acgtttacca gcacgtcaac aacgcccgct accttgaatt
    31381 tctcgaagaa gcccgctggg atgggttgga aaatagcgac agttttcagt ggatgacggc
    31441 ccataacatc gccttcgtcg tggtcaatat caatattaac tatcgtcgcc cagcggtatt
    31501 aagtgacctg ttaactatta ccagtcagtt gcagcaatta aacggtaaaa gcggcatctt
    31561 aagccaggtc attacactgg agccggaagg gcaggtggta gcggatgcgc ttattacgtt
    31621 tgtttgtatt gatcttaaaa cgcagaaagc attagctctg gaaggggaat tgcgcgaaaa
    31681 gctggagcag atggttaagt aaacgttttg tggtgccgga tgctcaagcc gcatccggcg
    31741 acacccggaa taattacctc aacccggttt tctgcttcat cgctgccatc accgtcggtt
    31801 tatcggccag ataatgattc aaaccgttag cgcgtaaatt acatgccgca caatgaccgc
    31861 aaccgtcgcc tttaaagccg ttatagcagg tcaacgtttc gttacggact aaatccagtt
    31921 tgccgtaata atctgccagc gcccaggttt ccgctttatc aatccacatc agcggcgttt
    31981 caaaacgaat atctttcgcc atgcccaaac tgacggcatg gtttagtgct ttcacaaact
    32041 catcgcggca atccgggtag ccggagaaat ccgtttcgca gacgccagta attacggctt
    32101 ctgcttttac ctgatacgca tatattgccg ccagcgtcag gaacaaaata ttacgccctg
    32161 ggacaaacgt attcgggata ccatcggctt caggttcata atcaggcacc ggaatgctgt
    32221 cacgcgtcag gctactgacc gccagctcgt tgagcagggt gacatccagc accttatgcg
    32281 cgcgtgcccc cagtttcagc gccagttcgc gtgccacgtc gatttctgcg cgatgccgct
    32341 gaccgtaatc gaacgtcacg caatggactt catcatattg ttgtaatgcc tgcaccagac
    32401 aggtggtgga atcctgacct ccactgaaca caacgacagc acgtttcata gataatcctg
    32461 cttgaacaat aaaagcgtta tggtaacgcc tgcgattaac ccggaccagc tattcattgc
    32521 gatggcgcgg gaagccaggc ttcggtaaat tcaaaccagc cgcgcggtgt cagtcgcaca
    32581 ccgttcacgc cgggaggggc actaatgcga tagtgatagt tgaacagcgg cgtcagcgtc
    32641 gcatctgtca ttaactggct aaaaaccgct ttcagggcat taaatcggtt ttcttcatca
    32701 ggcattattt gcacggcatc cagtgtcgat tgtagatgtg cgtatgctgg agcgtcgaaa
    32761 acatgtggcc acagcggatc gcagcgcagc cattgctcca gagtatattc cggtgcttcg
    32821 ccaattaatc tgtcgcccat catgaggtct gcgtgtgcct gtagggtcgt gtcgtcccag
    32881 ttttttgcgt tatgaaaaat aattgtgagt tcacagcctt ccgctgccag tgtcgcctgt
    32941 aggcgttctg ccatggtatg aagttctatc ggtaggtgat aaaccagcgt caaggttttc
    33001 ggtagtttga cttcatccgg tacctgccaa tgcggaatag tccagcctgg cagtaatgca
    33061 tgactggcgg tgatcaggtt ttctccgact tctaacgttt gtaataaacc ggattgatga
    33121 ataatggaga tcacttttcg cgcctgccag agggagagtc ggggactttt gcgcaacgtc
    33181 aaatagcaaa aacctaaact gatgccgcta ctgacctggc tgacccgttg cagctcctcc
    33241 ggtttgccga tggtgatttg cacgggatgc cgacaactgg ttcccaaatc tttttcgaaa
    33301 agcggcggag ttatccagta ctcaaccgct ttaagcagcg gatgacgtaa atggtaataa
    33361 tcatggcttt ccaggcgcac cagctctgct gtgaattgtg ttaagcgaaa aggacccgtg
    33421 ccgatcagtg ggaattgcgg atgcgccaga tggctgcaat agctcgccag ccggtgcgca
    33481 agccagtaat cagggcgatg taaaaagaag gtcagacact gcggatgggt gacttcaata
    33541 cgcttcacgc taataaataa ttgatccagt gctggcagtt gtaacagcat caataatcgc
    33601 tggtgtaagt gtgaggcttt tactgcatcg ccgttatgcc agtgtagggt tgaacgaaga
    33661 taaaagtccc agcgtaaccc gtcagtagag gtttcccagt gatgcgctaa atcgccaatc
    33721 gggcgctgag tattattatc gaagcgggtc aggccggaaa atatctgccc ggcgagatgc
    33781 tgctcggcac ggccgggcaa aaagcctggt tgtagcggtt cgagcgggcg atagtaggga
    33841 atacgcaacg tgggtgtatc gttttgccat tgtccgccca taaacggctg taacagagtg
    33901 cgcagctcac ctggggccag ttgcgccagc tccagcacat cttgctgctt tccggtttcc
    33961 agtgcctgtt ccatcatcgc attgcgtagc gattccggcg tgaccagaaa gcgtaattgt
    34021 ccgcgctttc cgcgtcctga ctgcgcctgc cactccagcc atcccgcctc ctgtgcctga
    34081 cgcaacagcg tacgaacatg gcgttcgctg caaaaacagc gttcggccag ttcgctgacg
    34141 gtgacggttt gcggctttcc ggcggaaggt tgccacagac gttgatactg gttaagacgg
    34201 ttgagcaatc gcatataaac ccggaacaat attatttaac tattcactat tacttccgta
    34261 tatatcaggt gatactcaat caccattaac cgtgtcacag agtggagaaa gaaatggctc
    34321 gtctggcagc atttgatatg gatggcactt tattgatgcc tgaccatcat ttaggtgaga
    34381 aaaccctctc tactttggcg cgactgcgtg aacgcgacat taccctcact tttgccacgg
    34441 ggcgtcatgc gctggagatg cagcatattc tcggggcgct atcgctggat gcgtatttga
    34501 ttaccggcaa cggaacgcgc gtgcattctc tggaaggtga acttttacat cgtgatgatt
    34561 tacctgcgga tgtcgcggag ctggtgctgt atcagcaatg ggatacccga gccagcatgc
    34621 atatcttcaa tgacgacggt tggtttaccg ggaaagagat ccctgcgttg ttgcaggcat
    34681 ttgtctatag cggttttcgt tatcagataa tcgatgtcaa aaaaatgcca ctcggcagcg
    34741 tcaccaagat ctgcttctgt ggcgatcacg acgatcttac acgcttgcag atccagctat
    34801 acgaagcatt aggcgagcgt gcacatttgt gtttttccgc cacggattgc ctcgaagtgc
    34861 tgccggtggg ctgcaataaa ggcgctgcat tgacggtgct gacccaacat ttaggtttat
    34921 cgttgcgcga ttgcatggcc tttggtgatg tgatgaacga tcgcgaaatg ttagtcagcg
    34981 tcggtagcgg atttattatg ggcaatgcga tgccgcaact gcgcgcggag ctcccgcatt
    35041 taccggtgat tggacattgc cgaaatcagg ctgtctctca ctatttgacg cactggctgg
    35101 actatccaca tctaccttat tcccccgaat aacgagatcc cttccagcac cgggcaattg
    35161 cccggttttt tttgcgttga atttgtcatt ttgtgccgtg gtgtttaaac cgcacagaat
    35221 aaattgtcgt gatttcacct ttaaaataaa attaaaagag aaaaaaattc tctgtggaag
    35281 ggctatgtta gataaaattg accgtaagct gctggcctta ctgcagcagg attgcaccct
    35341 ctctttgcag gcactggctg aagccgttaa tctgacaacc accccttgct ggaagcgcct
    35401 gaaacggctg gaggacgacg gtatccttat cggcaaagtc gccctgctgg atccggaaaa
    35461 aataggcctc ggcctgaccg cttttgtgct gataaaaacg caacatcaca gcagcgaatg
    35521 gtattgccgc tttgtcacgg tggttaccga aatgccagaa gtgctggggt tctggcgcat
    35581 ggctggtgaa tacgattatc tgatgcgcgt ccaggttgcc gacatgaaac gctacgacga
    35641 gttttataag cgtctggtaa acagcgtgcc ggggctgtcg gacgtcactt ccagcttcgc
    35701 gatggaacag attaaataca ccacttcttt acccatcgaa taaatatcca gaatcaggtc
    35761 aggacacaac gcgtgcgatt atttgctcaa ttaagctggt atttccgtcg ggaatggcgt
    35821 cgctatctcg gggctgtcgc cttgcttgtc attatcgcga tgctgcaact ggttccgcca
    35881 aaagtggttg gtattgttgt cgatggcgtg acagaacaac actttactac cgggcagatc
    35941 ctgatgtgga tcgccaccat ggtgctgatt gccgttgtgg tttatctcct gcgttacgtc
    36001 tggcgggtat tgctgtttgg tgcgtcttat caactggctg ttgaactgcg tgaagattat
    36061 taccgtcagc taagccggca gcatcctgag ttttacctgc gtcatcgcac cggtgacctc
    36121 atggctcgtg cgaccaatga cgtcgatcgc gtcgtgtttg ccgccggaga aggggtgctg
    36181 acgctggtgg attcactggt gatgggctgc gctgtgttga ttatgatgtc tacgcaaatt
    36241 agctggcagt tgaccttatt ttccctgttg ccgatgccag tgatggcgat catgattaag
    36301 cgcaacggcg atgctttgca tgaacgcttt aagctggcac aggcggcgtt ttccagtctt
    36361 aatgaccgca cccaggaaag cctcaccagt atccgcatga tcaaagcctt tggtctggaa
    36421 gatcgccagt cggcgttatt tgccgcggat gccgaagata ccggcaaaaa aaacatgcgg
    36481 gtggcgcgta ttgatgctcg tttcgacccg accatctata tcgcgattgg tatggcgaac
    36541 ttgctggcga ttggcggcgg tagttggatg gtggtgcagg gcagtttaac gctgggccag
    36601 ctcaccagtt ttatgatgta tttaggtctg atgatttggc caatgctggc gctggcatgg
    36661 atgtttaaca ttgtggaacg tggtagtgct gcgtacagcc gtattcgcgc gatgctggcg
    36721 gaagcgccgg tggtgaacga tggtagcgaa cccgtgccgg aagggcgtgg cgaactggat
    36781 gtaaatattc accagttcac gtatccgcag actgaccatc ctgcgctgga aaacgtcaat
    36841 ttcgccctga aacccggtca gatgctgggt atctgcgggc cgactggttc cggcaaaagt
    36901 accctgttgt cgctcattca gcgtcatttc gacgtcagcg agggggatat tcgctttcat
    36961 gatattcctc tgacgaagtt acaactcgat agctggcgta gccgcctggc ggtagttagc
    37021 cagacgccat tccttttttc tgacactgtg gcgaataaca tcgcgctggg ttgcccgaat
    37081 gccacccagc aagagattga gcatgtcgcg cggttagcca gcgtacatga cgatattttg
    37141 cgtctaccgc aaggttacga tacagaggtg ggcgagcgcg gtgtgatgct ttccggcggg
    37201 caaaaacagc gtatctccat tgctcgtgcg ttattagtca acgcggaaat cctcatcctt
    37261 gatgatgcgc tttcggcggt ggacggacgc actgagcacc agatcctgca taacctgcgt
    37321 cagtgggggc agggaagaac ggtaatcatc agtgcccatc gcctttctgc actgacggaa
    37381 gccagtgaaa ttattgtgat gcagcacgga catatcgccc agcgtggcaa tcatgatgtg
    37441 ctggcacaac aaagcggctg gtatcgcgat atgtatcgct atcaacaact ggaggcggcg
    37501 ctcgacgacg ctccggaaaa tcgcgaggag gccgtcgatg cgtagtttta gccaactgtg
    37561 gccgactctc aagcgcctgt tagcgtacgg ttcgccgtgg cgtaaaccgc tggggattgc
    37621 ggtcctgatg atgtgggttg cggcggcggc agaagtcagt gggccgctgc ttatcagcta
    37681 ttttatcgac aatatggtag cgaaaaataa cctgccgttg aaagtggttg cagggctggc
    37741 tgcggcgtat gttgggctgc aactgtttgc cgccgggcta cattacgcgc agtcgctgct
    37801 gtttaatcgg gcggcagtag gcgtagtgca acagttgcgt accgacgtga tggatgctgc
    37861 gttacgccag ccattaagcg agtttgatac ccaacccgtc gggcaggtga tttcccgcgt
    37921 cactaatgac actgaagtga tccgcgatct ctacgttacc gtagtggcaa ctgtcctgcg
    37981 cagtgccgcg ctggtgggcg cgatgctggt ggcgatgttc agcctcgact ggcgaatggc
    38041 actggtggcg ataatgattt tcccggtggt gctggtggta atggtgatat accagcgtta
    38101 cagcacgccg attgtccgtc gtgtgcgcgc ctatctggcg gatatcaacg acggctttaa
    38161 cgaaatcatc aatggcatga gcgttatcca gcagtttcgt cagcaggcgc gatttggcga
    38221 acgtatgggg gaggccagtc gttcacacta tatggcgagg atgcaaaccc tgcgcctcga
    38281 cggttttctg ctgcgtccgc tgctgagtct gttttcatcg ctcattcttt gtggcttgtt
    38341 gatgctgttt ggcttctccg ccagcggcac cattgaagtg ggcgtgctgt atgcgtttat
    38401 cagctatctt gggcgactta acgaaccatt aatcgaactg accacgcaac aggcgatgct
    38461 gcaacaggct gttgttgctg gtgagcgcgt gtttgaactg atggacggac cgcgccagca
    38521 atatggcaat gatgatcgcc cgttacagag tggcaccatc gaagtcgata acgtgtcatt
    38581 tgcttatcgc gatgacaatc tggtgctaaa gaacattaat ctctctgtgc cttcgcgcaa
    38641 ttttgtggcg ctggtcgggc ataccggcag tggcaaaagc accctcgcca gtttattgat
    38701 gggctattac ccgctaacgg aaggtgagat tcgccttgat ggtcgtccat taagttcgct
    38761 aagtcacagc gcgctgcgcc agggcgtggc aatggtgcag caagatccgg tggtgctggc
    38821 ggataccttc ctcgccaacg tgacgctggg gcgggatatc tccgaagaac gcgtctggca
    38881 ggcgctggaa accgtgcaac tggcggagct ggcgcgtagc atgagcgacg gtatttacac
    38941 gccgctgggc gagcagggga ataatctctc agttgggcaa aagcaactgc tggcactggc
    39001 gcgcgtgctg gtcgagacgc cgcaaatcct gatccttgat gaggcaaccg ccagcattga
    39061 ctccggtact gaacaggcga ttcaacatgc tctggcggcg gtgcgtgaac ataccacgct
    39121 ggtagtgatt gctcaccgct tatcgaccat tgttgatgcc gacaccattc tggtgcttca
    39181 tcgtgggcaa gccgtggagc agggcactca ccagcaactg ctggcggccc agggacgcta
    39241 ctggcagatg tatcaactgc aacttgcggg cgaagagctg gcagccagcg tgcgtgaaga
    39301 ggaatcattg agcgcctgaa tagcgcaata tttcatcgtt ggtgcaaaaa tgtaacgcac
    39361 tgtgcactgt catagtgcgt tttcattttc aaacttctta acttcctgct ctctttctcg
    39421 tttttcattt ctggcacacc gcttgcaata ccttcttcgt gtagcagaac cattaccgaa
    39481 ttctgaccgg aggggatcta tgaagctggt gaccgtgata atcaaaccat tcaagctgga
    39541 agacgttcgt gaagcgttat cttccattgg tattcagggc ctgaccgtca ccgaagtgaa
    39601 aggtttcggg cgtcagaaag ggcatgccga gctgtaccgg ggggcggaat acagcgtcaa
    39661 tttcctgcca aaagtaaaaa ttgatgtggc gattgctgat gaccaactcg atgaagtgat
    39721 cgatatcgtc agtaaggcgg cttacaccgg aaaaattggc gacggcaaaa tcttcgtcgc
    39781 tgaattgcaa cgcgtcattc gtattcgtac cggcgaagcc gacgaagcgg cgctgtaatc
    39841 tctggcacac agcaacagga acgaaaaatg aagatagcga cgataaaaac tgggcttgct
    39901 tcactggcga tgcttccggg actggtaatg gctgcacctg cggtggccga taaagccgac
    39961 aatgcgttta tgatgatttg tactgcgctg gtgctgttta tgactattcc ggggattgcc
    40021 ctgttttacg gtgggttgat tcgcggcaaa aacgtgctgt cgatgctgac gcaggtgacg
    40081 gtgacatttg cactggtctg tattctctgg gtggtttacg gttactcgct ggcgtttggt
    40141 gagggcaaca acttcttcgg caacattaac tggttgatgc tgaaaaacat cgaactgacg
    40201 gcggtgatgg gcagcattta tcagtatatc cacgtggcgt ttcagggatc gtttgcctgc
    40261 attaccgtcg gcttgatagt tggggcgctg gcggaacgaa tccgcttctc agctgtgttg
    40321 attttcgtgg tggtatggct gacgctctct tacattccga ttgcgcatat ggtgtggggc
    40381 ggtggtttgc tggcttctca cggtgcgctg gatttcgcgg gtggcaccgt ggtgcacatt
    40441 aacgccgcaa tcgccggtct ggtgggcgcg tatctgatag gaaaacgcgt gggcttcggt
    40501 aaagaggcgt ttaaaccgca caacctgccg atggtcttca ccgggactgc cattctctat
    40561 atcggttggt ttggctttaa cgccgggtca gcgggcacgg cgaatgaaat cgcggcactg
    40621 gcatttgtga atactgtggt cgcaacggcg gcggcaattc ttggctggat cttcggtgaa
    40681 tgggcgctgc gtagtaagcc ttcactgctg ggggcgtgtt ctggcgcgat tgccggtctg
    40741 gtcggcgtga cgccagcctg cggctacatt ggggttggcg gcgcgttgat tatcggcgtg
    40801 gtagctggtc tggcgggctt gtggggcgtt accatgctca aacgcttgct gcgggtggat
    40861 gatccctgcg atgtcttcgg tgtgcacggc gtttgtggca ttgtcggctg tatcatgacc
    40921 gggatttttg ccgccagctc gctgggcggc gtgggcttcg ctgaaggtgt gacgatgggc
    40981 catcagttgc tggtacagct ggaaagcatc gccattacga tcgtctggtc cggtgttgtg
    41041 gcatttatcg gctacaaatt ggcggatctg acggttggtc tgcgtgtacc ggaagagcag
    41101 gagcgagaag ggctggatgt caacagccac ggcgagaatg cctataacgc gtaacaagca
    41161 ctgcaaaaaa cagccggacg gttttcacct ccggctattt ttttaattgt gattacgcat
    41221 caccccttcc tgaacggtcg aggcaaccag tacgccgtct tgggtataaa actcaccgcg
    41281 cacaaagcca cgtgcgctgg acgccgaggt gctctccacg ctatacagca gccattcatt
    41341 caaattaaac gggcgatgga accacatgga atggtcaatg gtggcaatct gaatccccgg
    41401 ttcgagaaaa ccgatgccgt gcggctgtag agctaccggc aggaagttaa gatcagaagc
    41461 gtaaccgagc agatactgat gaacgcgcag gtcatccggc acgctaccat ttgcgcggat
    41521 ccacacctga cgatgtggtt ctgcgacgtg acctttcagt gggttatgaa actccaccgg
    41581 acggacttcc agcggacgat cgcagatgaa tttatctttc agcactggcg gcagcaggtg
    41641 cgccagcgat tgggtgattt gcgtttccga aggtaggcca tcaggcgctg gcgcggacgg
    41701 cattgttttt tgatgttcga aacccgcttc tggtgcctgg aaagaggcag tcatataaaa
    41761 aatcggtttg ccgttttgaa tagcagcaac ccggcgggcg ctgaagctgt taccgtcacg
    41821 cagcgtttcg acatcataaa taatcggctt cttactatcg ccagggcgaa gaaagtagct
    41881 gtgaaacgaa tgtaccagcc gctcttcagg gacggtctct tttgcagcat acaaggcctg
    41941 acccacgacc tggccgccaa acacctggcg taaacctaaa tcttcactct ggccgcgaaa
    42001 gagtccttcc tcaatttttt ccagatttaa caatgtcagt aaatttttta gcgcctgact
    42061 catataactc tccagtaaca aagctgccgc agcaagccaa agtgagttga gtataacgca
    42121 aatttgctac tggtccgatg ggtgcaatgg tctgaattac gggctaatta caggcagaaa
    42181 tgcgtgatgt gtgccacact tgttgacgtt actattttgt taaccactct tccggcgagg
    42241 aaagttagcc cgctggtgca ttgataataa ggagaaatga atgaaactcg tgcacatggc
    42301 cagtggttta gcggttgcga ttgcgttggc ggcttgcgca gataaaagcg cggatattca
    42361 gacgccagca ccggctgcaa atacgtctat ttcagcaaca caacaaccag ctatccagca
    42421 accgaatgtc tccggtaccg tctggatccg tcagaaagtc gcactgccgc ctgatgctgt
    42481 gctgaccgtg acactttctg acgcgtcgtt agccgatgca ccgtcaaaag tgctggcgca
    42541 gaaagcggtg cgtactgaag gtaaacagtc accattcagc tttgttctgc catttaaccc
    42601 ggcagatgtt cagccgaacg cgcgtattct gttgagtgcg gcgattaccg tgaatgacaa
    42661 actggtattt atcaccgata ccgttcagcc ggtgatcaac cagggcggaa ctaaagccga
    42721 cctgacattg gtgccggtac agcaaaccgc cgtgccggtt caggccagcg gtggcgcaac
    42781 gactaccgta ccttcgactt caccaactca ggtgaatccg tcttcggcag ttccagctcc
    42841 tacgcaatat taagcgacgt taaccctctc cgcccggaga gggttagtag ttccagcgat
    42901 aacgctgcaa gtcgatttgc ccgcttcccg ataccatcac accttctgcc agtaatgcct
    42961 gtcgctgacg ctgtaaatcc ggtccggtta gcgaaattgt gccgtggcga ttaaccaccc
    43021 ggtgccaggg taaggtgctg ccttcaggga gacgctttaa cacaccgccc acctggcgcg
    43081 cggcgcgggg cgatcccgcc agtttcgcca catcaccgta agtggtgaca tagccttcgg
    43141 gaatagcggc gacgatttgc cagacgcgtt ggggaaatga atcttctttt tccatctttt
    43201 cttcctgagg taatttttca gcataatctg gaaaaacgcc cgagtgaagt cgcattgcgc
    43261 aagaaaccag catctggcac gcgatgggtt gcaattagcc ggggcagcag tgataatgcg
    43321 cctgcgcgtt ggttctcaac gctctcaatg ggggctctgt tggttctccc gcaacgctac
    43381 tctgtttacc aggtcaggtc cggaaggaag cagccaaggc agatgacgcg tgtgccggga
    43441 tgtagctggc agggccccca cccatttctg cctcccaccg tttcgtcaaa aaatcccaac
    43501 atggctaaac tttaaccaca actgacgtcg caagaattgt ctggctgcgc agtacgcttc
    43561 ggaggtatgt ctgatgaagt atgttgatgg ttttgtggtt gccgttcctg ccgataaaaa
    43621 ggatgcctat cgggaaatgg ccgctaaggc tgcgccattg tttaaagagt ttggcgcgct
    43681 tcgtattgtc gaatgctggg ccagcgatgt accggatggc aaagtgaccg attttcgtat
    43741 ggcggtgaaa gcggaagaga atgaagaggt tgtctttagc tggattgaat acccttcaaa
    43801 agaggtccgc gacgctgcta atcaaaagat gatgtcggac ccacggatga aagagttcgg
    43861 cgagtccatg ccgtttgacg gcaagcgaat gatctatggc ggattcgagt caatcatcga
    43921 cgaataggta gcgtgacggg ctgtgcggcg tgccgtcagc ccaaaaattc acaaatgttg
    43981 ctcggcccag cgtaagaaat cttctttcgg taatgccttg ctgtagagcc agccctgacc
    44041 gtagtgcacg ccatgctggc gtaaccactc ttcttgttta ctggtttcga ttccctccgc
    44101 taccattttc agtttcagtg tttttgccat ttcgatgata tgcggcgtga catttttata
    44161 ttccagcgca tcaacgaaag atttatcgat cttcagaatg tcgacatcca gatcctgtaa
    44221 ataacttaaa cttgaatacc ccgtaccaaa atcatcaaga taaatttcat ggcccgcctc
    44281 ccggtagcga gaaattatcg gggcgctggt tttcggatcg gcaaactcgc gttcagtgag
    44341 ttcaagcgcg atctgtctgg gattaacctg atagtgattg atcatgtcac gcagcaattg
    44401 cgggattttt tccgaggtga gcacggggga ttcaagattg atcgaaatat gctgctgtgg
    44461 atgctgacgc agccagtcgc ccatatcttc aaagacgctt cttataatca gtagcgtcaa
    44521 tggctcagaa aggcccgttt gctgtgccag cggaataaaa ctatctggtg acaaccaact
    44581 accgtctgtc tgcggccagc gcgccagtgc ctcagcaccg acaattttgc cattggctaa
    44641 ggagacaatc ggctgatagt gcacgcaaat atcacgattt tcgatagcat cctgcagccg
    44701 atgatgcggt gactgaatac ggcgcaaaat acgcagcaca aacatcgctg ccagcaggcc
    44761 aatcaccaac ccgagcggta accaaataaa gacttgccga tgccagcctt tctgcaacat
    44821 tttcgttgaa gcccatgtga tgatcgaaat attcatctcc ggtaagggca ggatatcgta
    44881 aatgattcca ttattttcga tatgctcacc gggtgttttt tgtagcctgg taataattcc
    44941 ctgagcaatt tcatcgctgc tggttatgac aacgttatgg gcattgccaa taatggcggc
    45001 atcaatttgc catgagctat agggaatgac atcaataaag gaagcggggt cgatcatgac
    45061 gacataatgt gccgttccca tggcgaccat gtaacggata atgcctaaat cgttatgcga
    45121 tgttaaccag acacgataac catctttcga aattttacct ggctcgggga aggtatcggg
    45181 cggactttca tgctccagag acgaacactg gggaacgttg ttatcgatat aagccacttc
    45241 ctgaatatag cgataactgt aagatacccg acgcatttcc atgagatggg cttcgctaca
    45301 ggcagcgcct tgccatcttt ccagctcctg cagcgcatct ttcccttgtg tcgccacctt
    45361 attggctcga atagcgacgc gggaggaata ggtatccagc tcttcaataa acgatgtttc
    45421 tacctgctga tgggccagcc agatgcttaa gccgacaggc agcaatactg aaagaatcag
    45481 tactcccgaa ataaggccga ccagatgtcg tgttctcacc agcatatcct tattaacaca
    45541 gtgtagggaa agtatatctg attgtggaaa aaggctggct ggagataagg aggtagagct
    45601 ggtatttcat gaagtgatgg gtggaaacga tcattgtcat ttgaccaggc gcagagcttt
    45661 acgcctggta tgtaacccta acttaagatg ttgattcggc gcgagcgagg gtaaaaatat
    45721 cgtaaaaaga cagttcacct ttacggacga tcattttttg cagttgttcc ttatgaacat
    45781 ccgcgacacg cggagagttc aagatggctt caaccagcgc ggcaggtaca aagcgcgtgt
    45841 tgtaccattc gccgttatag caaacgcgga aatccagcac gtcgatatct tcatagcggt
    45901 agcgtgggta gacatcgaaa aagaagaaac cattaagcag gataaataat acaaccagta
    45961 gccagacaga gcctgacagc gtttcggact gcaacatcac cgccagggtg gcaaaaaaag
    46021 caacgtacat accgataaac agccccggat gtttacggat aaaactgata ctaaagcggg
    46081 gtttgttgtc gcgtttttcg cgggtattca gagactcaat cgtttcggtc agcaggcgtt
    46141 gtatttcggt catcgtttgc cttcgtggta tctgcaactt tccagggaac accctatttt
    46201 aacgtgggaa tagtagaggg gaagtaacag atctaccaca attttgcata acagttgcga
    46261 aaaaccgatt acaatttttt aattattctg gctggattac cgcccacgac aacgttgtcc
    46321 gggacatctt ttgtgacaac tgcacctgag gctaccacga cgttatcacc aatggtcaca
    46381 ccagggttaa tgaccgcgcg tccgccaatc cagacgttat taccgatggt gacgggtttc
    46441 cccagttcag caccgctatt acgtgctaca gggtcgatgg gatgtgttgc cgtgtagata
    46501 tgaacgcctg gtgccaacat acagttatca ccgatgcgaa tagggcagac atcaagcatc
    46561 acgcaatcga agttggcgaa aaaattatta ccgagaaaaa tgttatagcc atagtcacag
    46621 cgaaacgttg gctcaatata agcctctgtc acctgaccga atagatcagc gagaatttgc
    46681 tggcgtaatg tgtgctcttc cgccagggaa tgattgtatc ggtgaataag ctgacgagcg
    46741 cgcaggcgat cgcgagataa cgtctcatct gccgagcgat acaactcacc agcaatcatc
    46801 ttttcttttt ctgtactcat tactgacctc cggttgctga aaatgcggca acacagtaag
    46861 acgaaaagtc agtgaagaga acgttcccat tacatctgtg tgataaagat cacatagggt
    46921 atgtcttcat ggcgaaaaag tataaaattc ttaataaaca gccggttata gctccgaaag
    46981 cgaattattt attagcgaat aaatttccat actgaggaag ggatcttgtc gtacagttta
    47041 ttcatggtca attcggcgag gcggtgatct gcggctgagt aaaataccgc cagttcatta
    47101 tctgataatt cgtatttatt tttctcgata acacgctcca gcgtgtcaat tgtctggcaa
    47161 cgacgtaaac gcattaaata atcggttttc gttaaaggtt tttcggacat acttctacct
    47221 atggttgtaa taattctaac aagataaact cgcaggattc tctttcgtcg cattgacaaa
    47281 acaacggaat agtcgattac ctgacttccg ccatttctga agatcctgca tattaatacc
    47341 ataactactg aacaacataa aggtgtcatc cagatattcg tcgatctgct caatgagctt
    47401 attgtcttca ttatacttaa ttttgtaatt aagtgcgaag gtcgcaatat gctcaatcag
    47461 ttcattcaac tggaggttga tcgccgaggt tgggtcgttt acccagccat gattgctttc
    47521 ttcaaggttt gcaaggcagt catgatacag ggtttcacag agaaacttaa gctgtgcgat
    47581 atcatgtctt ttgggtgagt attcatccat aacgcgtccc cttcttagcg gttgaactaa
    47641 cggacacctt tcgggatgga aaaaacttac tgacctggac ttgccctctc gtttgttagc
    47701 ttaactataa gccactcttt gcaggttttc atcgcattat tacgaaaaat tacaattagg
    47761 aaggaagcgg gacaggactc actttttcat actagcacta acccgcagca ggtaaaagca
    47821 gtttgctcga actattcata acatttcagg attatcgcca gatgaaattg gtgacactaa
    47881 taccaggatt gctctgaata tgacgtaata accgaggaat gaataaagaa ttaccgcaaa
    47941 taattaagaa tagcctctaa atgattatgg at
//
LOCUS       DACAOP010000025        47162 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.025, whole genome shotgun sequence.
ACCESSION   DACAOP010000025 DACAOP010000000
VERSION     DACAOP010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47162
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.025"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(78..1025)
                     /locus_tag="IT892_001606"
     CDS             complement(78..1025)
                     /locus_tag="IT892_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001361319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HAP3134835.1"
                     /translation="MKNVLVTVPSFSARCVSASKLLRENNFNLIIKNNVEHLLKSEST
                     ALRESICAVIAGKDCYQADTLSLLPGVKIISRFGTGIDNIDLRAAQQSGIVVKNAVGI
                     NSNAVAEFIIGLIFASMRNIPGSYHAMQNGYWVESHGCELQGKRIGLVGYGNIGKTLA
                     KRLSGFDVELLAFDKQPDFQAAGKDGVQFVSIEDIFMQSHVIIVLLPFSPELENFISH
                     KYLSMMRNGALIINAARGKLLDEGALLQVIEERNVFAALDVFSSEPLAQFSPLLHAKN
                     IITTPHIAAATVESYQQTGIHVAQSIIDYFAGREIKNVL"
     gene            complement(1097..1693)
                     /locus_tag="IT892_001607"
     CDS             complement(1097..1693)
                     /locus_tag="IT892_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019864967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP3134836.1"
                     /translation="MNNSELIHLIKHFMRNEHKAVEEVIDSPLSEVANLIKVLQSCQG
                     KVVFIGVGKSGIIARKLAATFASTGTPSFFVHGTEAVHGDLGMVAKDDVVILISNSGE
                     TAEILATLPSLKRMGNYLISFTRSHHSSLAISCDLSVEIPVKSEADNLGLAPSCSSTV
                     VLVVGDAVALALSELKKFTRADFGLYHPGGALGIKANS"
     gene            complement(1686..2870)
                     /locus_tag="IT892_001608"
     CDS             complement(1686..2870)
                     /locus_tag="IT892_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000350897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative C-S lyase"
                     /protein_id="HAP3134837.1"
                     /translation="MNVFNTPISRKGTYCTQWDFCEDRFGVKDVLPFSISDMDLPIPE
                     AIIRALKKRLEHPILGYSRWQHDDYLNAIVNWYHQQYKTEIKPEWITYSPSVMYSIAK
                     AIELLTLNGDNILIFTPVYNAFFDVIKQSGRNMLTTSLNKENERGYAINWQDFELKIK
                     SAKMVLLCNPHNPTGTVWSEEDLFKIAASCAKQKIWLCSDEIHSDFVFNHGFTSALKI
                     KNDKVVVLNSISKTFNVPALTGSYMISADQDFNDKFRTISRYRDFVNSPSILNVIATI
                     VAYNECEEWLKSLKDHIASNIQFTQQYLNENIPELIVRSAEGCYFSWIDCSAIGYPFD
                     KFYRRLIDEGKVGIMAGYVYGTEGEGYLRLNLACGREKLYMGLVRLASVIKNINQEKE
                     NE"
     gene            complement(2870..4450)
                     /locus_tag="IT892_001609"
     CDS             complement(2870..4450)
                     /locus_tag="IT892_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP3134838.1"
                     /translation="MKQKKAWSFFQSLGKAFMYPIALLSVCGMMLGLGSGLASDDMAK
                     LIPFLAIPIIKTILDFIVSLGLFAFVNLPVLFAIAIPLGLLKEKEDKAYGAFSGLIGF
                     MAMHLGTNFYLKQHDLLVAADQMSTHGQTIILGIQSYNTSVLGGIVAGLLVASMYKKI
                     VNLRIPESLGFYSGPRLVPIITLIVMSGFGLIIPFIWPPFFNLFMLIGHWISTSGPVG
                     YFFYAVAERVTIPFGLNHLVTSVFRFTPIGGSAVIGGEEYYGTLNMFMAYVKENAVIP
                     LDLAGKMEQGKLMIQYGLAGAALAMYRTAHAQNRKAIKALLISGVLTVIIGGVSEPIE
                     FLFLFVSPLLFVFHAFMNGFANMVLPYMGVKMGFTGDLIQFISFGVLRGTRTGWPIAV
                     CVEVAYFFIYYFVFRWTILKFNLMTVGREESSPVTLNAHEETAIANIPAYDKSELQAA
                     EQMVKALGGKENIKSLDNCVTRLRLTIADMGLIDEAAIKSAGGIAVVKLDQNTLQVII
                     GTKVIALRRDMDNYMGIR"
     gene            complement(4482..5306)
                     /locus_tag="IT892_001610"
     CDS             complement(4482..5306)
                     /locus_tag="IT892_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003843851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP3134839.1"
                     /translation="MIIEKVMNNNCVQASMNGQEVIISGPGVGYNKKYGMSVPEHPAN
                     RIFYVRNEQKNKLYKLIEHVDIEYVFVAEKIVQYAEKNLEKNLNPSLLLILADHISNA
                     ISRVASGIQINNVFLDEIKALYKAEYAISRDALTIINEQFSFQLPDDEIGFIALHILN
                     NYENSSDYESVRIIELSQKITEIIEGIYNRKVDRSSFNYSRFMMHLKYFSNRVLCNEK
                     IKQKDIGDIYEQFLEKDILLQRAIHEIERYLYATFKYELILEEKLYLSIRTKVLMD"
     gene            complement(5564..6817)
                     /locus_tag="IT892_001611"
     CDS             complement(5564..6817)
                     /locus_tag="IT892_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMIN domain-containing protein"
                     /protein_id="HAP3134840.1"
                     /translation="MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPA
                     SSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNLNSVLKGMAAQIRADDPFIKSAR
                     VGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLED
                     YNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQI
                     ARRLRSLIEKEGNMKVYMTRNEDIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSG
                     SSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLK
                     FGKAVLNKLGKINKLHKNQVEQAGFAVLKAPDIPSILVETAFISNVEEERKLKTATFQ
                     QEVAESILAGIKAYFADGATLARRG"
     gene            7049..8380
                     /gene="argA"
                     /locus_tag="IT892_001612"
     CDS             7049..8380
                     /gene="argA"
                     /locus_tag="IT892_001612"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HAP3134841.1"
                     /translation="MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSS
                     IVNDIGLLHSLGIRLVVIYGARPQIDANLAAHHHEPLYHKNIRVTDAKTLELVKQAAG
                     TLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDA
                     IHRQLDSGAIVLMGPVAVSVTGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDD
                     GDIVSELFPNEAQARVEAQEEKGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGAL
                     LQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEI
                     DKFTIIQRDNTTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERIAAQAKQS
                     GLSKLFVLTTRSIHWFQERGFTPVDIDLLPESKKQLYNYQRKSKVLMADLG"
     gene            complement(8442..10268)
                     /gene="recD"
                     /locus_tag="IT892_001613"
     CDS             complement(8442..10268)
                     /gene="recD"
                     /locus_tag="IT892_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HAP3134842.1"
                     /translation="MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSH
                     DAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMIL
                     CGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAV
                     ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGK
                     ALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDL
                     PMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERAGQLSRLTG
                     THVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFSD
                     IEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFG
                     VAGLNERIEQFMQQKRKIHRNPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGT
                     RVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELV
                     YTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE"
     gene            complement(10268..13810)
                     /gene="recB"
                     /locus_tag="IT892_001614"
     CDS             complement(10268..13810)
                     /gene="recB"
                     /locus_tag="IT892_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HAP3134843.1"
                     /translation="MSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGL
                     GGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNPLYERLLE
                     EIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLR
                     YQACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETL
                     ASRHAQIVARIDAVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIEKISAWAEEE
                     TNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVITRALAE
                     IRETVAREKRRRGELGFDDMLSRLDSALRSESGKVLAAAIRTRFPVAMIDEFQDTDPQ
                     QYRIFRRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSA
                     PGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAMKMWLMEGES
                     CGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQ
                     VRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLN
                     ALDIETLNNDEHAWDAVVEEFDGYRQIWRKRGVMPMLRALMSARKIAENLLATAGGER
                     RLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVT
                     IHKSKGLEYPLVWLPFITNFRVQDQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAED
                     LRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTC
                     IEALCDDDIAWQTAQTGDNQPWQVNDVLTAELNARTLQRLPGDNWRVTSYSGLQQRGH
                     GIAQDLMPRLDVDAAGVVSVVEEPTLTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNW
                     VQEKLELGGFESQWEPVLTEWITAVLQAPLNETGVSLSQLSARDKQVEMEFYLPISEP
                     LIASQLDALIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGE
                     DSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYDRHFGGVIYLFLRGV
                     DKEHPQQGIYTTRPNAGLIDLMDEMFAGMTLEEA"
     gene            complement(13803..16691)
                     /gene="ptrA"
                     /locus_tag="IT892_001615"
     CDS             complement(13803..16691)
                     /gene="ptrA"
                     /locus_tag="IT892_001615"
                     /EC_number="3.4.24.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin"
                     /protein_id="HAP3134844.1"
                     /translation="MPSSTWFKALLLFVALWAPLSQAETGWQPIQETIRKSDKDNRQY
                     QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYP
                     QADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAE
                     RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQAL
                     KDFQEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKG
                     IIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVE
                     GISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDEL
                     ANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMT
                     PQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKSADIALSLPELNPYIP
                     DDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFSSEPKADVSLILRNPKAMDSARNQ
                     VMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGY
                     FSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSI
                     TLKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVD
                     KKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLG
                     YAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRTMKPEEFAQIQQ
                     AVITQMLQAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVV
                     EPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE"
     gene            complement(16867..20235)
                     /gene="recC"
                     /locus_tag="IT892_001616"
     CDS             complement(16867..20235)
                     /gene="recC"
                     /locus_tag="IT892_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HAP3134845.1"
                     /translation="MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQ
                     WLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLPEIPKESAFNKQSMSWKLMTLLPQL
                     LEREDFTLLRHYLTDDSDKRKLFQLSSKAADLFDQYLVYRPDWLAQWETGHLVEGLGE
                     AQAWQAPLWKALVEYTHELGQPRWHRANLYQRFIETLESATTCPPGLPSRVFICGISA
                     LPPVYLQALQALGKHIEIHLLFTNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDRELPL
                     FRDSENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLEGSQELDAFVDVTPDNL
                     LHNIQSDILELENCAVAGVNIEEFSRSDNKRLLDPLDNSITFHVCHSPQREVEVLHDR
                     LLAMLEEDPTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAISDRRARQSHPV
                     LEAFISLLSLPDSRFVSEDVLALLDVPVLAARFDITEEGLRYLRQWVNESGIRWGIDD
                     DNVRELELPATGQHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAELVGHLAS
                     LLMQLNIWRRGLAQERPLEEWLPVCRDMLNAFFLPDAETEAAMTLIEQQWQAIIAEGL
                     GAQYGDAVPLSLLRDELAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGMND
                     GVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEALISAQQKLYISYIGRSIQDNS
                     ERFPSVLVQELIDYIGQSHYLPGDEALNCDESEARVKAHLTCLHTRMPFDPQNYQPGE
                     RQSYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRFWAHPVRAFFQMRLQVN
                     FRTEDSEIPDTEPFILEGLSRYQINQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGE
                     IFWETQCQEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQPDGLLRWRPSLL
                     SVAQGMQLWLEHLVYCASGGNGESRLFLRKDGEWRFPPLAAEQALHYLSQLIEGYREG
                     MSAPLLVLPESGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMMVRGEGDDI
                     WYQRLWRQLTPETMEAIVEQSQRFLLPLFRFNQS"
     gene            complement(20248..20571)
                     /locus_tag="IT892_001617"
     CDS             complement(20248..20571)
                     /locus_tag="IT892_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAP3134846.1"
                     /translation="MSASLKNQQGFSLPEVMLAMVLMVMIVTALSGFQRTLMNSLASR
                     NQYQQLWRHGWQQTQLRAISPPANWQVNRMQTSQAGCVSISVTLVSPGGREGEMTRLH
                     CPNRQ"
     gene            complement(20556..20963)
                     /locus_tag="IT892_001618"
     CDS             complement(20556..20963)
                     /locus_tag="IT892_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311708.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2509 family protein"
                     /protein_id="HAP3134847.1"
                     /translation="MNREKGVSSLALVLMLLILGSLLLQGMSQQDRSFASRVSMESQS
                     LRRQAIVQSALEWGKMHSWQTQPAVQCLLYAATGARVCLRLLVDNEALLIAGYEGVSL
                     WRTGEVIDGNIVFSPCGWSDFCPLKERALCQLP"
     gene            complement(20960..21523)
                     /locus_tag="IT892_001619"
     CDS             complement(20960..21523)
                     /locus_tag="IT892_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HAP3134848.1"
                     /translation="MPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRDSLTSTRK
                     LALEDEIWLRVFTVAKHLQRAGYCHGSCTGEGLEIVGQGDCVIVQWDANSNGIWDREP
                     VKESDQIGFRLKEHVLETLRGATSCEDKGWDKVTNPDAIIIDTFQVTRQDVSGFSPVL
                     TVNMHAASKADPQTVVDASYSVTGFNL"
     gene            complement(21514..21984)
                     /locus_tag="IT892_001620"
     CDS             complement(21514..21984)
                     /locus_tag="IT892_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HAP3134849.1"
                     /translation="MKTQRGYTLIETLVAMLILVMLSASGLYGWQYWQQSQRLWQTAS
                     QARDYLLYLREDANWHNRDHSISVIREGTLWCLVSSAAGANTCHGSSPLVFVPRWPEV
                     EMSDLTPSLAFFGLRNTAWAGHIRFKNSTGEWWLVVSPWGRLRLCQQGETEGCL"
     gene            complement(22170..22964)
                     /gene="thyA"
                     /locus_tag="IT892_001621"
     CDS             complement(22170..22964)
                     /gene="thyA"
                     /locus_tag="IT892_001621"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP3134850.1"
                     /translation="MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPL
                     VTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWP
                     TPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
                     CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHL
                     QLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI"
     gene            complement(22971..23846)
                     /gene="lgt"
                     /locus_tag="IT892_001622"
     CDS             complement(22971..23846)
                     /gene="lgt"
                     /locus_tag="IT892_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAP3134851.1"
                     /translation="MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRR
                     ANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSF
                     HGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNF
                     PFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYI
                     RKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVI
                     MMVWAYRRSPQQHVS"
     gene            complement(23997..26243)
                     /gene="ptsP"
                     /locus_tag="IT892_001623"
     CDS             complement(23997..26243)
                     /gene="ptsP"
                     /locus_tag="IT892_001623"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAP3134852.1"
                     /translation="MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLAD
                     HDRRCYYLMATRGLKKPRGRTVTLAFDEGIVGLVGRLAEPINLADAQKHPSFKYIPSV
                     KEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQLT
                     ALFGQYRQTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEE
                     AANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSVAEWAVKTVI
                     EKFAEQFAALSDNYLKERAGDLRALGQRLLFHLDDANQGPNAWPERFILVADELSATT
                     LAELPQDRLVGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLIVDGYRGE
                     LLVDPEPVLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEK
                     LGSRIDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQL
                     PYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVTSLDEVD
                     EARRLIERAGREVEEMIGYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQ
                     YILAVDRNNTRVANIYDSLHPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILI
                     GLGYRHLSMNGRSVARVKYLLRRIDFAEAENLAQRSLEAQLATEVRHQVAAFMERRGM
                     GGLIRGGL"
     gene            complement(26256..26786)
                     /gene="rppH"
                     /locus_tag="IT892_001624"
     CDS             complement(26256..26786)
                     /gene="rppH"
                     /locus_tag="IT892_001624"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001655775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HAP3134853.1"
                     /translation="MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGE
                     SAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLL
                     QLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQE
                     NTPKPQNASAYRRKRG"
     gene            27471..28160
                     /gene="mutH"
                     /locus_tag="IT892_001625"
     CDS             27471..28160
                     /gene="mutH"
                     /locus_tag="IT892_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutH"
                     /protein_id="HAP3134854.1"
                     /translation="MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALAGLVTPENL
                     KRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTG
                     NSGVTWETSHVRHKLKRVLWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEE
                     LMDMIVLGQVERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFT
                     SALLARHFLIQ"
     gene            28229..28942
                     /locus_tag="IT892_001626"
     CDS             28229..28942
                     /locus_tag="IT892_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HAP3134855.1"
                     /translation="MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQ
                     RAHARRLGLAGAMVMRLALLASIAWVTRLTNPLFTLFSQEISARDLILLLGGLFLIWK
                     ASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
                     VVIAVGVMMFAARSIGDFVERHPSVKMLALSFLILVGFTLILESFDIHVPKGYIYFAM
                     FFSIAVESLNLIRNKKNPL"
     gene            29080..29298
                     /gene="ygdR"
                     /locus_tag="IT892_001627"
     CDS             29080..29298
                     /gene="ygdR"
                     /locus_tag="IT892_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YgdR"
                     /protein_id="HAP3134856.1"
                     /translation="MKKWAVIISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPEIDD
                     DTGLVSYHDQQGNAMQINRDDVSQIIER"
     gene            29406..30446
                     /locus_tag="IT892_001628"
     CDS             29406..30446
                     /locus_tag="IT892_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /protein_id="HAP3134857.1"
                     /translation="MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGI
                     NLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPD
                     QALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT
                     LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVG
                     LAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAA
                     YVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMEQLKTNVESLHLELSEDVLAEI
                     EAVHQVYTYPAP"
     gene            complement(30478..31671)
                     /gene="lplT"
                     /locus_tag="IT892_001629"
     CDS             complement(30478..31671)
                     /gene="lplT"
                     /locus_tag="IT892_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HAP3134858.1"
                     /translation="MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQ
                     FYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINP
                     FLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLAD
                     WHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGET
                     RFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKL
                     VTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVLGGFFVVPLNALLQERG
                     KKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWI
                     WQRRH"
     gene            complement(31664..33823)
                     /gene="aas"
                     /locus_tag="IT892_001630"
     CDS             complement(31664..33823)
                     /gene="aas"
                     /locus_tag="IT892_001630"
                     /EC_number="2.3.1.40"
                     /EC_number="6.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acyl-ACP--phospholipid
                     O-acyltransferase/long-chain-fatty-acid--ACP ligase"
                     /protein_id="HAP3134859.1"
                     /translation="MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGIL
                     LALFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVI
                     FPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQI
                     TLHILPPTQVEMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFG
                     AGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGEHIGLMLPNAGISAAVIFGAI
                     ARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLE
                     DLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILA
                     NVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPEL
                     VYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRIL
                     EGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNG
                     YLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMV
                     SLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPEL
                     AVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE"
     gene            34409..35440
                     /gene="galR"
                     /locus_tag="IT892_001631"
     CDS             34409..35440
                     /gene="galR"
                     /locus_tag="IT892_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalR"
                     /protein_id="HAP3134860.1"
                     /translation="MATIKDVARLAGVSVATVSRVINNSPKASEASRLAVHSAMESLS
                     YHPNANARALAQQTTETVGLVVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQ
                     KERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQMPGMVLINRILPGFENRCIALDD
                     RYGAWLATRHLIQQGHTRIGYLCSNHSISDAEDRLQGYYDALAESGIAANDRLVTFGE
                     PDESGGEQAMTELLGRGRNFTAVACYNDSMAAGAMGVLNDNGIDVPGEISLIGFDDVL
                     VSRYVRPRLTTVRYPIVTMATQAAELALALADNRPLPEITNVFSPTLVRRHSVSTPSL
                     EASHHATSD"
     gene            complement(35447..36709)
                     /gene="lysA"
                     /locus_tag="IT892_001632"
     CDS             complement(35447..36709)
                     /gene="lysA"
                     /locus_tag="IT892_001632"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAP3134861.1"
                     /translation="MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALK
                     QFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTYPDDIVFTAD
                     VIDQATLERVSELQIPVNAGSVDMLDQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGE
                     NSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVLEFGQD
                     LQAISAGGGLSIPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQ
                     SGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVE
                     TVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLL
                     PEVLFDNGQARLIRRRQTIEELLALELL"
     gene            36831..37766
                     /gene="lysR"
                     /locus_tag="IT892_001633"
     CDS             36831..37766
                     /gene="lysR"
                     /locus_tag="IT892_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator LysR"
                     /protein_id="HAP3134862.1"
                     /translation="MAAVNLRHIEIFHAVMTAGSLTEAAHLLHTSQPTVSRELARFEK
                     VIGLKLFERVRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLP
                     VFSQSFLPQLLQPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHTPAGTER
                     TELLSLDEVCVLPPGHPLAAKEILTPEDFHSENYISLSRTDSYRQLLDQLFTEHQVKR
                     RMIVETHSAASVCAMVRAGVGVSVVNPLTALDYAASGLVVRRFSIAVPFTVSLIRPLH
                     RPSSALVQAFSEHLQAGLPKLVTSLDAILSSATTA"
     gene            complement(37753..38445)
                     /gene="ygeA"
                     /locus_tag="IT892_001634"
     CDS             complement(37753..38445)
                     /gene="ygeA"
                     /locus_tag="IT892_001634"
                     /EC_number="5.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HAP3134863.1"
                     /translation="MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVD
                     FHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCSLPFL
                     HIADATGRAIIRAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQI
                     IFEELCLGQFTEASRTYYAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAA
                     IHAEDAVAFMLS"
     gene            complement(38574..39992)
                     /locus_tag="IT892_001635"
     CDS             complement(38574..39992)
                     /locus_tag="IT892_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAP3134864.1"
                     /translation="MVTINTESTLTPRSLRDTRRMNMFVSVAAAVAGLLFGLDIGVIA
                     GALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLG
                     SIGSAFATSVEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLG
                     IVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAEKGRHIEAEEVL
                     RMLRDTSEKAREELNEIRESLKLKQGGWALFKINRNVRRAVFLGMLLQAMQQFTGMNI
                     IMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVM
                     ALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKC
                     RDFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTGLNIAFVGITFWLIPETK
                     NVTLEHIERKLMAGEKLRNIGV"
     gene            complement(40307..41068)
                     /gene="kduD"
                     /locus_tag="IT892_001636"
     CDS             complement(40307..41068)
                     /gene="kduD"
                     /locus_tag="IT892_001636"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="HAP3134865.1"
                     /translation="MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVE
                     PTETIKQVTALGRRFLSLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDAL
                     EFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTA
                     SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRW
                     GLPSDLMGPVVFLASSASDYVNGYTIAVDGGWLAR"
     gene            complement(41098..41934)
                     /gene="kduI"
                     /locus_tag="IT892_001637"
     CDS             complement(41098..41934)
                     /gene="kduI"
                     /locus_tag="IT892_001637"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAP3134866.1"
                     /translation="MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFIADEYTMVYSHIDR
                     IIVGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRD
                     ALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNR
                     RTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFH
                     MMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKD
                     LR"
     gene            complement(42221..43402)
                     /locus_tag="IT892_001638"
     CDS             complement(42221..43402)
                     /locus_tag="IT892_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417321.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HAP3134867.1"
                     /translation="MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVS
                     AYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAI
                     QCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
                     AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMTQSNGQTLVVDTDEQ
                     PRTDASAEGLARLNPSFDSLGSVTAGNASSINDGAAAVMMMSEAKARALNLPVLARIR
                     AFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFAAQALSVGKMLEWDE
                     RRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERD
                     E"
     gene            43657..44886
                     /locus_tag="IT892_001639"
     CDS             43657..44886
                     /locus_tag="IT892_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HAP3134868.1"
                     /translation="MSNIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAVVLFITA
                     LVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHYYGKKIGNLITTLYFIAFFVVVL
                     IYAVAITNSLTEQLAKHMVIDLRIRMLVSLGVVLILNLIFLMGRHATIRVMGFLVFPL
                     IAYFLFLSIYLVGSWQPDLLTTQVEFNQNTLHQIWISIPVMVFAFSHTPIISTFAIDR
                     REKYGEHAMDKCKKIMKVAYLIICISVLFFVFSCLLSIPPSYIEAAKEEGVTILSALS
                     MLPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEVVKTTLQQVGVKKSRAFNRA
                     LSIMLVSLITFIVCCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPWRSVGN
                     LITLIVGILCVSVMFFS"
     gene            45346..45978
                     /locus_tag="IT892_001640"
     CDS             45346..45978
                     /locus_tag="IT892_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417323.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP3134869.1"
                     /translation="MGLCSRYKSLTCNSCSMHCQIMPEESPRLQYCANSCFCMWPEES
                     SYFNRGVVEGILTKNHNARLSGYIFVDFSVSFLRLFLEKDWIDYLASTDMGIVLVSDR
                     NMQSLANYWRKHNSAISAVIYNDDGLDVANEKIRQLFIGRYLSFTRGNTLTQMEFTIM
                     GYMVSGYNPYQIAEVLDMDIRSIYAYKQRIEKRMGGKINELFIRSHSVQH"
     gene            46312..47121
                     /locus_tag="IT892_001641"
     CDS             46312..47121
                     /locus_tag="IT892_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP3134870.1"
                     /translation="MYWIINDNIEFWPEHRKLISVHNADLNVVLTTPASRCLSLLLEA
                     FPDVVAQQDFFTRVWEEEGMRVPTNTLYQNISIIRRGFRAVGDTTHSLIATVPRRGFK
                     IHNDINIQNHAINSSTDAHTHNAPPAVKGNAGYKESIGSANNFNNKILKHIKSYLIML
                     SIFAIGVYSAHWLWNNNQPKPFFKDYKTVAEINGCHFNVTEDTIDGLKEFDKYKTRIL
                     DSGINCKKYPWLYFPLAKSSPGMIVMACNKNYNQHEVAGCLTLSYREVNRD"
BASE COUNT        12192 a        12318 c        11010 g        11642 t
ORIGIN      
        1 tacttagaat gctgataaac cgcaatgtgt tccacaaatt gcggtttttt tgtatttaaa
       61 atcttcgttc gctgaactca caacacgttt tttatctccc ttcctgcgaa gtaatcaatt
      121 atcgactggg caacgtgtat cccggtttgc tggtatgact caacggtggc ggccgcaata
      181 tgcggcgttg taatgatatt tttggcatgt agcagtgggc taaattgcgc caacggttca
      241 gagctaaaca catccagcgc cgcaaacaca tttcgttctt caatcacctg aagtaaagcg
      301 ccctcatcca gcaactttcc ccttgcggca ttgatgatca gagcaccatt gcgcatcatt
      361 gacaaatatt tatgactaat gaagttctcc agctcaggag aaaaaggtaa aagaacaatg
      421 atgacatgcg actgcataaa gatatcttca attgatacaa actgaactcc atctttgcca
      481 gcggcctgaa aatcgggttg tttgtcaaaa gctaaaagct caacatcaaa accagacaac
      541 cttttcgcca gggttttacc tatattaccg tagccaacca ggccaatccg tttcccttgt
      601 aattcacagc catgcgactc aacccagtag ccattttgca tcgcatgata gctgccagga
      661 atatttctca tgctcgcaaa gataagtcca atgataaatt ccgcaaccgc atttgaatta
      721 atcccaaccg catttttgac tacaataccg gattgctgtg ccgcacgaag atcaatattg
      781 tctatccccg tcccgaatct cgatattatt ttcacaccag gcagcaatga tagcgtatcc
      841 gcctgataac aatcttttcc ggcgatgacc gcgcaaatag attctcgtaa tgcagtggat
      901 tctgatttaa gcagatgctc cacattattc ttaataataa gattaaaatt attctctctt
      961 agcaacttgc tggcggaaac acagcgtgct gaaaagctgg ggacggtgac cagaacattt
     1021 ttcatagctg acactcactt caatgaacgc caccccaaaa gatggcgtga ccggttactg
     1081 tatttatatt ttgaaattat gaatttgctt taatgccgag tgcacctcct ggatgatata
     1141 agccgaaatc ggcacgagta aattttttca attcggagag tgcaagcgcc accgcatcac
     1201 caacaaccag aacaacagta gacgagcatg acggtgctaa acctaaatta tccgcctcac
     1261 ttttgacggg gatttcaaca gataaatcac aacttatcgc aagcgatgag tgatgactgc
     1321 gggtaaaaga gatcaaataa ttacccattc ttttcagact aggcagtgtc gccaggattt
     1381 ccgccgtctc accactgttt gaaataagaa taacaacatc gtctttcgcc accattccaa
     1441 ggtcgccgtg taccgcttcc gtaccgtgaa caaaaaacga gggagttccg gtactggcaa
     1501 atgttgctgc gagttttctg gcaataatac cggacttacc aacaccaata aaaacaactt
     1561 taccctgaca agattgtaat actttaatta aattagcgac ttcagaaagt ggggaatcaa
     1621 taacctcttc aacggcctta tgttcgttac gcataaaatg tttaataaga tgtataagtt
     1681 ccgagttatt cattttcttt ttcctgatta atatttttaa ttacactcgc aaggcgcaca
     1741 agccccatat ataatttttc tcgaccgcag gccagattca gacgcagata gccctcacct
     1801 tccgtaccat aaacataccc cgccataata cccactttcc cttcatcaat taatcgtcgg
     1861 taaaatttat caaagggata gccaatggcc gagcaatcta tccacgaaaa atagcaaccc
     1921 tcagcggacc tcacgatcaa ttctggaata ttttcattca aatactgctg ggtaaattga
     1981 atgttagagg caatatgatc ctttaacgac tttaaccatt cttcacattc gttataagca
     2041 acaatggtag caatcacatt caatatagat ggtgagttta caaaatcgcg atatcttgat
     2101 atcgttctaa acttatcatt aaaatcctgg tcagcggata tcatatatga tcctgttagt
     2161 gcaggaacat taaatgtttt cgaaatcgaa tttaacacca ctactttgtc attttttatt
     2221 tttaacgcgg acgtgaaacc atggttaaaa acaaaatcac tgtgaatttc atctgaacat
     2281 agccagattt tttgttttgc gcagcttgca gcgattttga agagatcttc ttccgaccag
     2341 acggttcctg tcgggttatg aggattacac aataacacca tcttcgcgct tttaattttt
     2401 agctcaaaat cttgccagtt gatagcgtag cctctctcat tttctttatt caaagaggtt
     2461 gttagcatat ttcgaccact ttgtttaatt acatcaaaaa atgcgttata aacaggcgta
     2521 aaaatgagaa tgttatctcc attcaatgtt aataactcta ttgccttagc aattgaatac
     2581 atcacacttg ggctataggt gatccattct ggttttattt cagttttata ttgttgatga
     2641 taccaattga ctatcgcatt cagataatca tcatgctgcc aacggctgta ccctaaaatc
     2701 gggtgttcca ggcgtttttt taatgccctg atgatagctt ccggtatcgg aagatccata
     2761 tctgaaatag aaaatggtaa tacatctttt acaccaaatc tgtcctcaca aaagtcccat
     2821 tgagtgcaat atgttccttt acgggagata ggggtattaa aaacattcat cagcgtatcc
     2881 ccatgtagtt atccatatcc cgacgcaggg cgatgacttt agtgccgata atgacttgta
     2941 aggtattttg atcaagtttc acaaccgcaa tccctccggc acttttaatt gcagcctcat
     3001 ctatcaatcc catatctgcg atagttaaac gcaaacgagt gacacaatta tccagtgatt
     3061 taatattttc ttttccaccc agagccttaa ccatttgctc cgctgcctgc aactctgatt
     3121 tatcataagc tgggatatta gctattgcag tttcttcgtg agcgttcagc gtgacaggac
     3181 tggactcttc acgtcctacg gtcatcaggt taaatttgag aatggtccaa cggaacacaa
     3241 agtaataaat gaagaaatag gccacttcga cacacaccgc gatcggccaa cctgttcttg
     3301 tgccacgcaa tacgccaaag ctaataaatt gaatcagatc gccagtaaat cccatcttca
     3361 cgcccatata tggcaagacc atgttggcga atccattcat aaaggcatgg aagacaaaca
     3421 gcagcggact gacaaataag aacagaaatt caatcggttc gctgacgcca ccaataataa
     3481 ccgtaagcac accggaaata agcaatgctt tgatagcctt tctgttttga gcatgagcag
     3541 tgcgatacat ggccagtgca gcaccagcca gaccgtactg aatcatcagt ttgccctgct
     3601 ccattttccc cgccaaatcc agcggaatga ccgcattctc tttgacgtac gccataaaca
     3661 tgttcagggt gccgtaatac tcttcgccgc caatcacagc cgaaccgccg attggcgtaa
     3721 agcggaacac tgacgtcacc agatggttta agccaaaagg aatcgtcaca cgttcggcaa
     3781 ctgcatagaa gaaataacca acaggaccgg aagttgatat ccagtggcca atgagcatga
     3841 agagattgaa aaacggcggc cagataaaag gaatgatcag accaaatcca ctcatcacaa
     3901 tcagtgtaat gataggcacc agacgtgggc cgctataaaa acctaatgat tctggaatgc
     3961 gtaaattaac gatcttttta tacatgctgg cgactaataa cccagcaaca attcccccta
     4021 acacgctggt attgtaggac tggatcccca gaatgatggt ttgcccatgt gtcgacattt
     4081 ggtcagcagc gaccaataag tcgtgctgtt taagataaaa gttcgttccc agatgcatcg
     4141 ccataaaacc aattaagcca gaaaaagcgc cataggcttt atcctctttc tcttttaata
     4201 atcctaaggg aattgctatc gcaaacaata caggtaaatt aacaaaggca aacaaaccaa
     4261 ggctaacaat gaaatcaagt atggttttaa ttattggaat agccagaaat ggaattaact
     4321 ttgccatatc atcactggct aaaccacttc ctagccctag catcatgcca catacactta
     4381 gcagagcaat gggatacata aatgccttcc ccaggctctg aaaaaaactc caggctttct
     4441 tttgtttcat gtgggttatc tcatataaat gttatatata attagtccat taatactttg
     4501 gtacgaattg agagatatag tttttcttct aaaattaatt catatttaaa agtggcatac
     4561 agataccttt caatttcatg aattgcgcgc tgtaacagga tgtctttctc aagaaactgc
     4621 tcatagatgt caccaatatc tttctgtttt atcttttcat tacataaaac tcgattagaa
     4681 aaatacttaa ggtgcatcat aaatcttgaa tagttaaatg aacttctgtc cacctttcgg
     4741 ttataaatac cctcgataat ctccgtgatt ttttgagata attcaataat ccgtaccgat
     4801 tcataatcag atgaattttc atagttattt aaaatatgca atgcaataaa accaatctca
     4861 tcatccggaa gttgaaagct aaattgctca ttgatgatgg ttaatgcatc ccggcttatt
     4921 gcatattctg ctttgtacaa cgctttgatt tcatcaagga aaacattatt aatttgtata
     4981 cctgaagcga ctcgggatat tgcattcgaa atgtgatccg caagaatcaa tagtagcgat
     5041 ggattgagat ttttttcgag atttttctcc gcatattgca ctattttttc ggcaacaaac
     5101 acatactcaa tatctacatg ttcaatcaat ttatagagtt tgtttttttg ttcatttctg
     5161 acataaaaaa tccggttagc cggatgctca gggaccgaca ttccatattt tttgttgtaa
     5221 ccgacgccag gtccagaaat gataacctcc tgtccattca tcgatgcctg tacacaatta
     5281 ttgttcatga ctttttcgat gatcattcca tgactccaaa aaaaaaggca aggcacgtca
     5341 gaagtaataa ttacttcaaa cattgccttg cctgatttaa cagttacaag atgattaact
     5401 aatgtgtata cattacacgg aattgtgttt aattaaagag atggtcggct tatttttcaa
     5461 gccgacattc aaatattcga catcagtcac aaaaccagca tctaatattc atgaaaatgt
     5521 tatctattca acgaaatata aattcattga ataaataaaa acatcatccc cttctcgcca
     5581 gcgtcgcccc atcggcaaaa tacgctttaa tccccgcaag aatagactcc gcaacttcct
     5641 gctggaaggt cgccgttttc agtttacgct cttcctcaac gttactgata aacgccgttt
     5701 cgaccagaat ggagggaata tctggtgcct ttagtacggc aaacccggcc tgttcaacct
     5761 gatttttatg cagcttgttg attttaccga gcttattcag caccgcttta ccaaacttca
     5821 ggctgtcggc aatggtcagc gactgcacca tatcgaacat ggtgtggtcg acatagcggt
     5881 caccgctttt gctcacgcca ccaatcaagt ccgaggcgtt ctgggtttgt gccagatatt
     5941 ttgccgcagt actggttgca cctttggttg agagcgcaaa cacagaggaa ccgctcggct
     6001 gacggctggt aaaggcgtcg gcatggatag agacaaacag gtcagcacgc tgtttctggg
     6061 cttttgctac gcgcacttgc aacggaatga agatgtcttc attgcgcgtc atgtacacct
     6121 tcatattgcc ctctttctcg atcagagagc gcagacggcg agctatttgc aataccacgt
     6181 ctttttcgcg cgttttgtat ttccccaccg caccggagtc ttcgccaccg tggccagggt
     6241 caagcataat gacaatcgga cgatcgcgcc ctgctttacc cggttgtgga ccactttgtg
     6301 ctggcggcac ctgcttttcg aggtcgcctt tgttgtaatc ctccagcagc gccagcagcg
     6361 ggtcctgcat atcctgtgca ttggccggat agaggtccat caccagacgc tctttaaacc
     6421 cagcgaccgg cgcaagggca aacagctgcg gttttacgtt ttgctttaat tcaaaaacca
     6481 tgcgtacggt ctgcgggtca aattgcccga cgcgcgccga cttgatgaac gggtcgtctg
     6541 cacgaatttg tgccgccatc cccttgagta ccgagttcag gtttacatct tcgatatcca
     6601 ccaccacgcg ttcagggtta ctcaacgcga actgcttata tttcagctga cgatttgatt
     6661 ctaccgtcac gcgggtgtag ctggacgcag gccagacgcg caccgccacg acctggctga
     6721 ccgcagccag actgacctga cttacgctca atagccacat ggcacccgcg ccttgcagta
     6781 aacgacgacg gctgattgca gtgttggatc ctgacatgcc tctcccgagc aaaagaaatc
     6841 taagctgtgt aacaagtaaa cgactaattt gaccggaaac tttagcgaaa gacgcataat
     6901 ctgtcatcta ataaacggta aacattcttt ttatattcac ggcattactg ataaaaaagt
     6961 cgctctcgca taaaatttac acttgcaccc tgcgaaaaaa cagaataaaa atacactaat
     7021 ttcgaataat catgcaaaga ggtgtgccgt ggtaaaggaa cgtaaaaccg agctggtcga
     7081 gggattccgc cattcggttc cctatatcaa tacccaccgg ggaaaaacgt ttgtcatcat
     7141 gctcggcggt gaagccattg agcatgagaa tttctccagt atcgttaatg atatcgggtt
     7201 gctgcacagc ctcggcatcc gtctggtggt gatctatggc gcacgtccgc agatcgacgc
     7261 aaatctggct gcgcatcacc acgaaccgct gtatcacaag aatatacgtg tgaccgacgc
     7321 caaaacactg gaactggtga agcaggctgc gggaacattg caactggata ttactgctcg
     7381 cctgtcgatg agtctcaata acacgccgct acagggcgcg catatcaacg tcgtcagtgg
     7441 caattttatt atcgcccagc cgctgggcgt cgatgacggc gtggattact gccatagcgg
     7501 gcgtatccgg cgaattgatg aagacgcgat ccatcgtcaa ctggacagcg gtgcaatagt
     7561 gctaatgggg ccggtcgctg tttcagtcac tggcgagagc tttaatctga cctcggaaga
     7621 gattgccact caactagcca tcaaactgaa agctgaaaag atgattggtt tttgctcttc
     7681 ccagggcgtt actaatgacg acggtgatat tgtctccgaa cttttcccta acgaagcgca
     7741 agcgcgggta gaagcccagg aagagaaagg cgattacaac tccggtacgg tgcgcttttt
     7801 gcgtggcgca gtgaaagcct gccgcagcgg cgtgcgtcgc tgtcatttaa tcagttatca
     7861 ggaagatggc gcgctgttgc aagagttgtt ctcacgcgac ggtatcggta cgcagattgt
     7921 gatggaaagc gccgagcaga ttcgtcgcgc aacaatcaac gatattggcg gtattctgga
     7981 gttgattcgc ccgctggagc agcaaggtat tctggtacgc cgttctcgcg agcagctgga
     8041 gatggaaatc gataaattca ccattattca gcgcgataac acgactattg cctgcgccgc
     8101 gctctatccg ttcccggaag agaagattgg ggaaatggcc tgtgtggcag ttcacccgga
     8161 ttaccgcagt tcatcacggg gcgaggttct gctggaacgc attgccgctc aggcgaagca
     8221 gagcggctta agcaaattat ttgtgctgac cacgcgcagt attcactggt tccaggaacg
     8281 tggatttacc ccagtggata ttgatttact gcccgagagc aaaaagcagt tgtacaacta
     8341 ccagcgtaaa tccaaagtgt tgatggcgga tttggggtaa gcgatgaaaa tcgtcggatg
     8401 cgacatgcgt aacactcgtg cgtcgcatcc ggcaattacg tttattcccg tgaactaaac
     8461 aacgccgcca gaccactgcg ccgctcagta cgagtggcga ttgccgcact taatatgcgc
     8521 tcatcggcat acagcgacag acggcgacgc gcgcgggtca ccgcggtgta aaccagctct
     8581 cgtgttacta ccggcgtgcg ttggctcggt aaaatcaacg ccgcatggtc gaactccgat
     8641 ccctgcgatt tatgtaccgt catcgcccac gtagtttcgt gctctggcag gcgactcggt
     8701 tgcacagact taatattgcc gtccggcatc gcaaaccaaa cgcgcgtccc ctgtccgcga
     8761 tccagagcga taccgatatc gccattaaac aacccaagcg cgctgtcatt acgggcaatc
     8821 atcaccggtc ggccttcgta ccaacgagag tgcggattac gatgaatttt gcgcttctgt
     8881 tgcataaact gctcaattcg ctcattcagt ccagccacgc caaacggccc ttcccgcagg
     8941 gcgcacaaaa gctggtactc attgaacgcc tgaatgatta aatccggctc ggcacgcgct
     9001 tgcagcagat ccagataacg tccgtaaccc gcaagagctt cctcaagcat cgcaatataa
     9061 tcttcgccgc tctgtaaaag ccgtttttcg atatcagaaa aatcctgctg aaaaacggtt
     9121 ttcactgccg ttttatcacc acggttgatc gccgcagcta actgaccaat gccagaatca
     9181 ctgccgaaac gatagctttt ttgcagcagg cagagactgt cgcgcaaaga tgccgcttct
     9241 gtgccagttc ctgccggaac gtgagttccc gtcaggcggc tcaactgccc ggcacgctcg
     9301 gcggtaaagc ccgcgttggc ataagcgcag atatcgccca gcacagcccc agcctcaacc
     9361 gaggccagtt gatcacgatc gccgagaaag atcactcgcg catgatcggg caaggcgtcg
     9421 atcagtctcg acatcatagg cagatcgatc attgacgctt catctaccac cagcacatca
     9481 agatgcagcg ggttaccggc atgatgacgt aaacgctggc tacccggctg cgcacccagc
     9541 aatcggtgca aagtactggc atcttccgga atgcgtttct tttgttcatc ggtcagcggt
     9601 aactgtcgca aagccttgcc gagagattcg gttaagcgcg cggcagcttt acccgttggt
     9661 gcagccagac ggatacggca gcgttctccg tcggccattt gaattaaggc tgccagcaac
     9721 ttcgctacgg tggtcgtttt accggtgcca ggaccgccgg aaatcaccga aatccgccgc
     9781 gtcagcgcca ctgccgccgc aactttttgc cagttaattt catcgcttac tggaaaaagt
     9841 ttgtccaggg tttgcgccag tagagcttca tcaacctcaa tggcatgatt cacttcgttg
     9901 aaaaagcgtg ccactgtgcg ctcgttacac cacatgcgat tcaaataaag acgatcgcca
     9961 cagaggatca tcggcgttgg ttcatctccc cggcttaccg cttgtgaagc cagcaagcat
    10021 tcttcccaat tttgtaactc accgatttca ctgacacagg tcgccaacag cggatgcgac
    10081 gcctcgttat tttccagtcg tgagagcggt aaacagacat gcccttcccc ggcgtcgtgg
    10141 cttaacaggg ctgccgcgag ggtgacggca ggatgttcat ctcccgccac ggtcagggca
    10201 aactgcacgt ccagcgggcg tagctgtttg tgctccacag cttccagtaa ttgcttttgc
    10261 aatttcatta cgcctcctcc agggtcatac cggcaaacat ctcatccatc aagtcaatca
    10321 acccggcgtt gggtcgggtt gtgtaaatcc cttgttgcgg atgttcttta tcaacgccac
    10381 gcaggaacag atagataacg ccgccaaagt gacgatcata gtcgtaatca gcaatgcgat
    10441 ggcgcaaata acgatgcaac gccagggtat aaagctgata ttgcagatca tagcggtgtg
    10501 cctgcatcgc cgctgccata gcctgttggg tgtaagccga actgtcttca cccagccagt
    10561 tggatttata gtcgagcagg taataacgcc cttcatgacg aaataccagg tcgataaagc
    10621 cttttaacat gccgcgtacc tgcatgaact ccagcggcgg gcagccagcg gatagcggat
    10681 caaactggcg aattagtgca tcaagctggc tggcgatgag cggttcacta atcggcaggt
    10741 aaaactccat ctccacctgt ttatcgcggg cggaaagctg actcaggcta acacccgttt
    10801 cattgagagg tgcctggaga acagccgtga tccactcggt caacactggt tcccactgcg
    10861 attcaaagcc gccgagttcc agtttttcct gtacccagtt cgggtcaacc ggctgggtaa
    10921 aatcgaggtc ttcaaacaaa ctgtgcaaga atgtccctgg tgacgcaccg cgcgggaact
    10981 gatgcggtgt taacgtcggt tcttcaacga cgctgaccac gcctgcggca tcaacatcca
    11041 gccgtggcat caaatcctga gcgataccgt gaccacgctg ctgcaaaccg gagtagctgg
    11101 tgacacgcca gttatcgccg ggcaatcgtt gtagcgtcct cgcattcagt tctgcagtta
    11161 aaacatcatt aacctgccag ggctggttat caccagtttg tgccgtttgc caggcaatat
    11221 catcatcgca taaagcttca atacaggtgc gaagccctgc cgcatcttgc ggttcccctt
    11281 tttgtagcaa acgcccgagc gcactttggt ggacgtcggt gtcacctttt ttatcgccac
    11341 gacggcgcac cagcggtgca acgccgagac tgcaatgcca aaccgaacgc gtcagcgcca
    11401 cgtaaagcaa acgcagatct tccgccagac gttcggcctc cgcgagatcg acactttctg
    11461 gcgcagcgtt aagatccaga acagcctcaa acgagtggcg atcgtgatag aacgcctgat
    11521 cctggacgcg gaaattggta ataaatggca accagaccag cggatattcc agcccttttg
    11581 atttatggat cgtgacaatc tgcaccagat gtttatcact ttcgaggcgc atttgttggc
    11641 tggaggcatt actgtctggc tcgaggatat gttgcgataa ccagcgtacc agcgcatgtt
    11701 cactttccag ctgcgttccg gcttcttgta gcagttcgct gatatgcaag atatcggtaa
    11761 gacgccgctc accgcctgcc gttgccagca agttttctgc aatcttacgc gccgacatca
    11821 gcgcccgcag catcggcata acgccacgtt tgcgccagat ttgccgataa ccatcgaact
    11881 cttcgactac cgcatcccac gcatgttcgt cattgttcag cgtttcgata tccagcgcgt
    11941 tcagccccat cattgacgtt gccagcgcac tacgcagggt gttctcacgt tcgggcgtca
    12001 tcaccgcctg caacaaccaa agcatttcct gcgcttccag agtttcaaaa acactgtcgc
    12061 ggttcgaaag gtaaacggaa gggatttcca gcaacgttaa ggcgtcgcgc acctgggcgg
    12121 cctcctggcg gctgcgcacc agcacactga tgtccgaagc acgcaccgga cgcgcgtcgt
    12181 cgccgttcat cagcaacgct tcgccccgct gtccggcttg tagccagtcg cggatttgcg
    12241 cagcacatac ctgcgccata gtactttgat agtcgccaac gccgcagctt tcgccttcca
    12301 tcagccacat tttcatcgca ggctgcgttt cacctttaaa tacaaaacgt aacgcctgat
    12361 ttttcccggc tgatttcact ggaataaacg gtatttcgcg aaacatgaac gcgtcatcag
    12421 tctggctgaa aagcttattc acgctgttca ccattcctgg tgcggaacgc cagttggtgt
    12481 ctaaagtgta gtgggcgtga acttcgctac gcgccttcat ataagtgaag atatccgcac
    12541 cccggaatgc atatatggcc tgtttcgggt cgccaatcag caacaatgcg gtttccggct
    12601 gatggtgcca gatacggcga aaaattcggt actgctgggg gtcggtatcc tgaaattcat
    12661 cgatcattgc caccgggaat cgcgtacgga tcgccgctgc caacaccttt ccgctttcgc
    12721 tacgcagcgc ggaatcgagc cgacttaaca tgtcatcaaa acccaattcg ccacggcggc
    12781 gtttttcacg cgctactgtt tcgcggatct cagccaatgc gcgggttatc accagatcac
    12841 ggatcgacaa tggttctgca agcagttgat cgatcgcctc aaacagtgga tgtcgcgggg
    12901 tttccccccc ggctttcgtg cgatcttcta agaaacgctg agagaatttt tccagcgact
    12961 ccggtaactg ataactgttg gtctcttctt ctgcccaggc gctgatcttc tcgatccatt
    13021 tagcctgatt gctacggtta aacttgcgtc gatcaatacc agaagattcg atcagcgcat
    13081 ccagttcacc cactgcgtcg cgccactgct gttttacggc gtcgatacgc gccacaattt
    13141 gcgcgtggcg ggaagccagc gtttcatcat cgggcggcgg tgctttgata accggtgctt
    13201 cgccttgcag ataacgatta atatcgcgca gcaacgcctg cggccctttc caggtttcaa
    13261 agaccacctg ggcaatttca cgcggcagcg ggtagcagtg gcgacgccag aaatcggcgc
    13321 aggcctggta gcgtagcaga gactcatctt caatcagctg ctgctcaaac agcatgccgg
    13381 attcaaaggc attcaggttg agcatgcgct ggcaaaaacc gtgaatagta aagactgccg
    13441 cttcatccat ctgccgttcg gctaacaaca accactgcgc ggcttgcgct ttatcgtcga
    13501 tctcttccag caggcgttcg tacagtggat tgtcggtggt ttcacgcaga caggcgatgc
    13561 gcaactcgtg gatattgcta cggatacgac cgcgcaattc tgccgtggca gcctcggtaa
    13621 aggtgaccac cagcagttct tcaacggtca gcgggcgggg aaaggcggcg gaaccgccta
    13681 gtccaagtaa caggcgcaaa tagagcgccg caatcgtaaa ggttttgcct gtgccggcag
    13741 aggcttcaat caggcgctcg ccctgtaagg gcaagcgcaa aggatctagt gtctcagcga
    13801 catcactcat tcttttcact catcaagggc attgtttgct gcaacgcgct gacgttctcc
    13861 cacactttcc agccttcagg atgcacatat tcggctttcc cgttctggct gccggaaatc
    13921 tgcgacagaa tagccatgcc ttgcggctcg accaccgcct gatggaagaa atcagcaagt
    13981 ttttgcggcg tcagcagttt tatctgggcc acgattttat cacgcgaatc gaagcgcata
    14041 ttgccgcgat cgaaatcttt acttaacttc gatgcttctt cgccgagcgt ttgcggtgcc
    14101 tgcagcatct gggttattac cgcctgctgg atttgcgcaa actcttctgg cttcatcgtc
    14161 cgcaattttg cctctgcggt tgggaaaaac gccttgtaac gctcccacaa gaatgaaggc
    14221 tgtttatcat tgctttgcaa caggaagccc atgccccact gacgccccac gctcattgga
    14281 aacgcaaaca cggcatagcc caactgttct tcggtacgca actgattgta gaaccacggc
    14341 tgtacgatct gccccaacag agagctatag gctgagctgg tgtattcatc gtagccagtc
    14401 ggtacaaata ccgctgccag tgcggagtcg gtgctgttac cggctttttc aaagatgaca
    14461 gattgttttt tatcgaccac gacatctttg ttacgacacc actccgaacc atcagcgccc
    14521 aactgttttt gcacatcgcg tgccagcgtt gttgcctggg cttcggtcat gttgccaata
    14581 accataaact ctggtcgagc ccctgatttt aaggcgtcgc gataggccag cacctctttc
    14641 aaagtgattg aaggcaaaat tttgcgccgt tcatctcgcg agaagtacgg cacttgcgag
    14701 agcatctgcg cgggcataat cgcctgctcg aacgctttgc ccttttctgc ggaatccatc
    14761 atctggttat accaggactt cgcctgctca agctgatctt ccgtagcggt atagctaaag
    14821 tacccctcga gcaatgcctg gaacagctgc ggcaggcgct gggtgtaacc attggcatta
    14881 accataaggc cgttgttagc gttggtggaa aaacttatgc caccaaccga cgcctggttg
    14941 cttaactgat caagcgccag ccctgcgaga taatcattga gcgcaaacat cacctgattg
    15001 cgggcgctgt ccatggcttt cggattacgc aaaatcaggc tgacatcagc tttgggttcg
    15061 ctggaaaaat aacggcttgg cgcatacacc acacgcagat tcgactcatc aacaatcagc
    15121 tctggatggt catatttctt ctctgactta atcagcgaga aatcgtcagg aatataaggg
    15181 ttaagctctg gcaaagagag cgcaatgtcg gcggattttt tctgccagtc ggcgaaagtt
    15241 tgtgcgctga ttttatcgac ctgatacggc gcatcgacaa agtaagccgt tttgttgtgc
    15301 ggctctttcg ggctgatata ccagatacgc gcattctgcg gcgtcatcat cgccaggcgt
    15361 tcttttactg ctttagcgtc gtaccgatcg gcaatattga ctgcatccag cgtatgctca
    15421 acaggaacgc gaatcatggt atctgccagc cattcgacgt aatccatatc acgggtgatt
    15481 gacggataac gaaagtcgat atccagcaca ttcgccagtt catcgaagta ttgtttatca
    15541 atcccttttt cgcgtaacag attgaggtag ctaaaaatgg ccgccacaac ctgatcgcga
    15601 ttcgccagac ctttatcggt taaagacgca gagatcgcta atacgccgct gttgccgttg
    15661 acgataggat cggaattggc gctaatgccc tcaactaatc cctgcttttg cagccagtca
    15721 gaaagtgtac ctgggctgcg attaccgatc agataggtaa tcaattcatc cgttttacta
    15781 cggaacttcg ctgaattgtt atcgatgcga aactcaacgc gcagaacttt acgcggcagc
    15841 gccgggacgt aatgaatgat aatgcccttt tgcgcgtcgg tgactaccgg cacggtgatt
    15901 tccggttttt tgctctcttt gttcggcacg cgaccaaagg tgtccgccgc catttttgcc
    15961 aactccggca gcggtttatt gctgtaaata accgccttca tcagattggc ggaatagtac
    16021 ttctcctgga aatctttcag cgcctgctgt accggatttc cgggtttgtc gcttaaagtt
    16081 tcgaggttac caccagaaaa ctttgaaccg gggtgtgccg ggttaatggt ttctgcgctg
    16141 acctgtgcca tgcgcatccc gtcacgcgta cgcgccatgg ttaattcggc attcactgca
    16201 ttacgttcac gttcggcgta tttcttgtcg agcaagggtt ctgcaatagc gtccgccagg
    16261 cggtccaccg caccgggcaa ggcgtcgttc tcaacttcca gatagaaagc cgtgcgatac
    16321 ggtgccgtgc tggcattgtg actgccgccg tgcattttga gatattcggc cagactgtca
    16381 gcctgcgggt actttttcga ccccatcaga ctcatatgtt caaggtaatg tgccagcccc
    16441 tggtacgcct cgggatcttc cagcgaccca acgggcacta ccagcgccga gagcgattta
    16501 accgcctgcg gatcagaaac cagcaagacc accataccgt tatccagacg tatagcctga
    16561 tactggcggt tatctttatc acttttacgg atggtttcct gaatcggctg ccatcccgtt
    16621 tctgcctgac ttaagggtgc ccaaagggca acaaacaaca ataatgcttt gaaccaggtg
    16681 ctgctgggca ttcacggacc tcataatcaa ctttattttc tggccagatt caacaggtta
    16741 acgcaaatca tctgccagaa tttaatcttg tgctgcacga gtcagcctat gtctatatat
    16801 ccatcagtcc gtgactggtg cgcatcataa agcaagcaga tatattgcgc aatttttata
    16861 cagcactcat gactgattaa agcgaaacag cggtaacagg aaacgttgcg actgttcaac
    16921 gatggcctcc attgtctctg gtgttaattg ccgccagagc cgttgatacc agatatcatc
    16981 accttcgcca cgcaccatca tgttgccttc gtaagcctga aggaatttcg tacgggcttt
    17041 ttgtaacgtg gaatcgtcat ccagcatggc atcgttttgc gcgtcataac aggtttttag
    17101 ccacgcgccg ccactttcag gtaacaccag caatggcgcg gacattcctt cacgataccc
    17161 ctcaatcagt tgtgagaggt aatgcaaagc ctgttcggct gcaagcggcg gaaaacgcca
    17221 ctcgccgtct ttgcgtagaa aaaggcgact ttcaccatta ccaccgctgg cacagtagac
    17281 aaggtgttcc agccaaagtt gcattccctg cgccacactt aataaagagg gacgccagcg
    17341 caacaggcca tccggctgca cctgcggcaa ccagccagtt atctgcacac cgttgcaggc
    17401 gagatcaatt tccatactct gccccggctg gcgacaggca ataactctgt cggcaagctg
    17461 ctgcatctcc tggcactgtg tttcccagaa aatttcacca aaagcgccat acggtaaatc
    17521 ccctgccgcc cggaagcggc ggaacaagcg ttcggcatca tcctgctcaa ccagtgcatt
    17581 caataactgc tgattgattt gataacggct aagcccttcc agaataaatg gctcggtgtc
    17641 ggggatttcg ctgtcttcag tacggaagtt cacctgcaaa cgcatctgga agaacgcccg
    17701 taccggatgt gcccagaatc gttgtagcgt ttccagcggc acggtttccg gtaaggtaaa
    17761 cggcagcggc tgaacaaatt cagaatgtgc tttaccagcc tggctggccg caggtagcca
    17821 ttcacgagca tagctttgtc gttcgcctgg ctggtagttt tgcggatcaa acggcatccg
    17881 ggtatggagg caagtaagat gcgcttttac ccttgcctcg ctttcatcac agttgagcgc
    17941 ttcatcgccc ggtagataat ggctttgccc gatgtagtcg atcagttcct gcaccagtac
    18001 cgacgggaaa cgttcactgt tatcctgaat agaacgcccg atatagctga tatagagttt
    18061 ttgctgcgcg gaaattaacg cttccaggaa cagatagcgg tcgtcatcgc gacgactacg
    18121 gtcgccacgc ttcggtttct ggctcatcag gtcaaagccc aatggcgcaa gctggcgtgg
    18181 ataaacgccg tcgttcattc ccagcaggca aaccactttg aatgggatgg aacgcattgg
    18241 catcagagta caaatgttaa ccggcccggc gagaaaacgc tggctgatac gttcctgatc
    18301 caggcgctgt gccagttcat cacgcaatag tgacagcggc accgcgtcgc catactgcgc
    18361 acctaaacct tcggcgataa tcgcctgcca ttgttgttcg atcagcgtca tcgccgcttc
    18421 ggtttccgca tccggcagga agaaggcgtt gagcatatcg cgacaaaccg gcaaccactc
    18481 ttccagcgga cgctcctgcg ccagcccgcg acgccagatg tttagctgca ttagcagtga
    18541 agccagatgc cccaccagtt ctgcaattaa gccgctcgat tcatcataag gtagaaccga
    18601 ttgccactcg ccctgcgcac tctccatcgc gtagcccagc aacatgcgcg tcaggccaaa
    18661 ccgccaggtg tgttgaccgg tagcggggag ttccagctcg cgaacgttgt cgtcatctat
    18721 cccccaacga atgccggatt cgttgaccca ctggcgtaaa taacgcagcc cttcttcggt
    18781 gatgtcaaac cgcgccgcca gcaccggcac atccagtaat gccagaacgt cctccgacac
    18841 aaagcggctg tctggcaacg ataacaggct gataaacgct tcaagtacag gatgcgactg
    18901 ccgcgcccga cggtcggaaa tggcgtaagg taggtaacga tccgcaggtg cgctaccaaa
    18961 cactgcctga ataaacggac tgtagctgtc gatgtcggcc accatcacga tgatgtcgcg
    19021 cggagtcaat gtcgggtctt cctccagcat tgccagcagg cgatcgtgta aaacttcaac
    19081 ttcacgctgc gggctatggc aaacgtggaa ggtgatactg ttatccagtg gatcaagcag
    19141 gcgtttgtta tcgctacggg aaaactcttc gatattcaca cccgcaacag cgcagttttc
    19201 aagttccaga atgtcagact gaatgttatg cagcaggtta tctggcgtga catcgacaaa
    19261 ggcgtccagc tcctggctgc cctccagatc agaaaggaga taaatgtagt cgcgcccaag
    19321 cttgccccat gaggccagca gcgggttgcc gacatcctgt tcaccatcgc tgttaaagag
    19381 ctgtccggca ttttcgctgt cgcgaaatag cggtaattcg cgatcttcaa aactgtgtcg
    19441 gcgctggcga gtcagcagtt tcgccagata agcaggatct ttaatgtcgc cccagtaata
    19501 acggcagggg ttggtaaaca ggagatggat ttcaatatgt ttacccagcg cctgtagcgc
    19561 ctggagataa acaggcggta acgcggaaat accgcatata aagacgcgcg aaggtagccc
    19621 cggcgggcag gtcgtcgcgg actccagcgt ttcgataaag cgctgataga gattggcgcg
    19681 gtgccagcgc ggttgcccga gttcatgggt atattccacc aacgccttcc acaacggcgc
    19741 ttgccaggcc tgtgcttctc ccagcccttc aaccaaatgt cctgtttccc actgtgccag
    19801 ccagtccgga cgatagacca gatactggtc aaacaggtcc gccgcttttg aagaaagctg
    19861 gaacagtttt cgcttgtcgc tatcgtcagt cagataatgc cgcaacaggg taaagtcttc
    19921 gcgctccaac agttgcggca gcagagtcat cagtttccag ctcatgctct gtttgttaaa
    19981 ggcgctctct ttggggattt ccggtaacac ccggacgaac atatcccaga taaagctcgc
    20041 tggcagcgga aaatcaatgt ttgccgcaat accaaacttt tgcgacaggg tcatttgcag
    20101 ccactgcgcc ataccggtac tttgcaccag aatcatttct ggttcgaaag gatcgtccag
    20161 ccgttcgcgt tcgacgataa actccatcaa cgcttccagc acgtccagac gattggaatg
    20221 gtagaccctt aacatagcgg ctcctgacta ctgacgattc gggcaatgca ggcgggtcat
    20281 ctcgccttct ctgcccccgg gtgaaactag cgtaacgctg atgctgacac atcccgcctg
    20341 cgatgtctgc attcggttga cctgccagtt ggcaggtggc gaaatcgcgc gcagttgcgt
    20401 ttgctgccag ccatgccgcc agagctgttg gtactggttt ctgctggcaa gactgttcat
    20461 taatgttcgc tggaaacccg ataacgcagt gacaatcatc accatcaaca ccatcgccaa
    20521 cattacctcc ggcaggctaa agccttgttg attcttcagg gaagctgaca taacgccctc
    20581 tctttcagcg gacaaaaatc gctccagccg catggcgaaa aaacaatgtt tccatcgatg
    20641 acttcgcctg ttcgccacaa cgaaacgcct tcataaccgg caatcaataa ggcttcatta
    20701 tctaccaata aacgcagaca aacccgggca ccggtggcag cgtacagtaa gcactgaact
    20761 gcgggctgcg tctgccagga gtgcattttt ccccactcca gcgccgactg aacgatggcc
    20821 tggcggcgca atgactgact ttccatgctc acgcgagaag caaaactgcg atcctgttgg
    20881 ctcattcctt gtaatagcaa gctacccaaa atcagcagca tcaggaccag agccagtgac
    20941 gaaacaccct tttcgcggtt cacaggttga atcctgtcac gctatagctg gcatccacca
    21001 cagtttgcgg atcagccttg ctggcagcgt gcatattaac cgtcaacacc ggcgagaaac
    21061 cactgacatc ctgtcgggta acctgaaaag tgtcgataat gatggcatcc ggattagtga
    21121 ctttatccca gcccttatct tcacaggatg tcgcaccgcg tagcgtttcc agcacatgct
    21181 ccttcagacg aaatccaatc tggtcggact cttttaccgg ttcgcgatcc cagataccgt
    21241 tactgttcgc atcccactgc acaatgacac agtcaccctg tccgacaatt tccagccctt
    21301 cgccggtaca gctgccatga caataacccg ccctctggag atgcttcgca acggtaaata
    21361 cccgcagcca gatttcatct tccagcgcca gcttacgggt gctcgttaaa ctgtcacgct
    21421 gtaacgcagg cagaaagcgt gcagccccca gcaacaatac gctactgatc gccatagcaa
    21481 tcaacacttc cagcagagaa aaaccttgct cttttacagg catccttctg tttctccttg
    21541 ctgacaaagc cggagtcttc cccacggcga aaccaccagc caccactcgc ccgttgagtt
    21601 tttgaagcga atatgcccgg cccatgcggt attgcgcagg ccaaagaaag caagcgaagg
    21661 tgtcagatcg ctcatttcga cttcgggcca gcgtggcaca aagaccaatg gtgaactgcc
    21721 atgacaggta ttggccccag cagcggaact cacaaggcac cataacgtcc cctccctgat
    21781 aacactgata ctgtggtcgc ggttatgcca gttggcatct tcacgtaaat agagcaaata
    21841 gtcccgcgcc tggctggcgg tttgccaaag ccgttgcgac tgctgccagt attgccagcc
    21901 atagagtcca cttgcgctta gcatgaccag aatcagcatc gcgaccagcg tttcaatcag
    21961 cgtataacca cgttgtgttt tcatgccggc agtatggagc gaggagaaaa aaagacgagg
    22021 gccagtttct atttcttcgg cgcatcttcc ggactattta cgccgttgca ggacgttgca
    22081 aaatttcggg aaggtgtctc gaagaattta acggagggta aaaaaaaacc gacgcacact
    22141 ggcgtcggct ctggcaggat gtttcgtaat tagatagcca ccggcgcttt aatgcccgga
    22201 tgcggatcgt agccttcaat ctcaaagtct tcgaaacggt agtcgaagat ggattcgggt
    22261 ttacgtttga taatcaactt cggcagcgga cgcggttcgc ggcttaattg cagatgagtt
    22321 tgatccatat ggttgctgta caggtgcgta tcgccaccgg tccagacaaa atcacccact
    22381 tccagatcgc actgctgcgc catcatatgc accagtaacg cgtagctggc aatgttgaac
    22441 ggcaggccga ggaagacgtc acaggagcgc tgataaagct ggcaagagag tttgccgtct
    22501 gccacataga actggaagaa tgcatggcac ggtgccagcg ccattttatc cagttcgcct
    22561 acgttccacg ctgaaacaat aatgcggcgg gaatccgggt cgtttttcag ctggttcaat
    22621 accgtagtga tctggtcaat atgacgacca tctggcgttg gccaggcgcg ccactgttta
    22681 ccatacactg gcccgaggtc gccgttttca tcggcccatt cgtcccagat ggtgacattg
    22741 ttttcgtgta gataagcaat gttagtgtcg ccctgcagaa accacagcag ttcatggatg
    22801 atggaacgca ggtggcaacg tttagttgtc accagcggga atccatcctg caggttaaaa
    22861 cgcatctgat gaccaaaaat ggaaagcgtt ccggttccgg tacggtcgtt tttctgtgtg
    22921 ccttcgtcga gcactttttg catcagttct aaatactgtt tcatggttcc tcaggaaacg
    22981 tgttgctgtg ggctgcgacg atatgcccag accatcatga tcacacccgc gacaatcatc
    23041 gggatggaaa gaatttgccc catgctgatg tactgcaccc aggcaccggt aaactgcgcg
    23101 tcgggctggc ggaaaaactc aacaatgatg cgaaacgcgc cgtaaccaat caggaacaag
    23161 cctgagactg ctcccattgg gcgcggttta cgaatataca ggttgaggat aataaacagc
    23221 accacacctt ccagcagcag ctcgtaaagc tgtgatgggt ggcgcggcag cacaccgtaa
    23281 gtgtcgaaaa tggattgcca ctgcgggttg gtttgcagca gcaaaatatc ttctgtacgg
    23341 gagccaggga acagcatggc aaacgggaag ttcgggtcaa cgcggcccca caattcaccg
    23401 ttaataaagt tgcccagacg cccggcacca agaccaaacg gaatgagtgg ggcgataaaa
    23461 tcagagacct ggaagaagga acgtttagta cggcgggcga agataatcat caccacgata
    23521 acgccaatca ggccgccgtg gaaagacatg ccgccgtccc agacacggaa cagatacagc
    23581 ggatcggcca taaactgcgg gaaattgtag aacagaacat aaccaatacg tcccccgagg
    23641 aagacgccga ggaagcccgc atagagtaag ttttcaactt catttttggt ccagccgctg
    23701 cccggacgat tcgcccgacg tgttgccagc cacattgcaa aaatgaaacc caccagatac
    23761 atcaggccgt accagtgaag cgctacgggt cctattgaga aaatgaccgg atcaaactcc
    23821 ggaaaatgca gatagctact ggtcatctgt caccacaagt tcttgttatt tcgctgaaag
    23881 agaacagcga ttgaaatgcg cgccgcaggt ttcaggcgct ccaaaggtgc gaataatagc
    23941 acaaggggac caggctggtt gccggatacc gttaaaagat atgtatatga tccgcgctat
    24001 aaccctccgc gaatcagccc gcccatgccg cgacgctcca taaaggctgc aacctgatgg
    24061 cgaacttcgg tcgccagttg cgcttccaga ctacgctgcg caagattttc tgcttcggca
    24121 aaatcaatgc gccgcagcag gtattttacg cgcgctacag aacgtccgtt catagacaga
    24181 tggcgatacc caagcccaat gaggattgcc acgcacatgg gatcgcccgc catttcaccg
    24241 cacaaacgga gatcgattcc atgtatttcc gcttcccggg cgatcatcgc cagagctcgt
    24301 aacattgcag gatgaagact gtcataaatg ttcgccaccc gggtattgtt gcgatcaacg
    24361 gccaggatgt attgagtcag atcgttggtg ccaacagaga taaaatcgac ccgctttgcc
    24421 agatgcggca gcataaatac cattgacggc acttccagca tgatgccgat acgtggtttg
    24481 ggaatttcgt aaccgatcat ctcctcgact tcacgtcctg cacgttcaat caggcggcgt
    24541 gcttcgtcaa cttcatcgag gctggtgacc atcggcaaca gaatattcag gttgcccgta
    24601 gcggcattag cacgcagcat cgcccgcacc tggatcaaga agatctccgg ctgatcgagc
    24661 gtaatgcgaa tcccacgcca acccaggcat ggattctctt cgctgatcgg catgtaaggc
    24721 agctgcttat ctgctccgac atccagcgta cgcaaggtga cgggtttatc attgaacatt
    24781 tgcagcatcc cctgatactg cgccacctgt tcttcttccg acggaaaacc actttgcagc
    24841 atgaatggga tttcagtgcg ataaagtcct atgccatcaa tacggctgcc cagtttttct
    24901 tcatgttccg ggcttaaacc ggcattgagc atgactttaa tgcgctcgcc gctttttaac
    24961 tgggcgggta aattgacgtc atcttccgcc agacggctaa gctcaatctc ttcactaatt
    25021 agccgctgat attcttgcag cagtaccggc tccggatcga ccagcaattc accgcgataa
    25081 ccatcgacga tcaacgtccg acgatgcagc accgaaggct gaatatccgc gcccattacg
    25141 gtagggatcc ccagcgcacg taccatgatc gcagcatggg agttggctgc gccatctcgc
    25201 acgacaacac cgactaagcg atcctggggc agctctgcaa gcgttgtcgc tgacagttca
    25261 tctgccacca gaatgaaacg ttccggccag gcgttcggcc cttgattagc gtcatcaaga
    25321 tgaaacagca atcgctgacc cagcgcacgt aaatcgccag cccgctcttt gagatagtta
    25381 tcgcttagcg cggcaaactg ttcggcaaat ttttcaatga ccgtttttac cgcccactct
    25441 gccaccgagc ctttatcaac ctcggcaaac aattcgcgac gcagccgggt gtccgaaagc
    25501 aggtgcgagt aaagatcgaa aatagccgcc gtttcttttt gtgcaccggc ggcaaagcgt
    25561 ttgctgtagc ggcgaaactc gtttgccgct tcttccagcg ccccggtcag tcgttcgcgt
    25621 tccagagccg gatccaacgt tgatgcctga tacacctgtt ccattaaagg taacgtggca
    25681 tcctgccagc cttcggcaat cgccacacca ggtgctgccg gtaatgcacg gattcgcgtc
    25741 tggcgatatt gcccaaacaa ggcagtcaac tgcgactgag aaagaatcgc tgccatctgg
    25801 gtggcaagcg tcaccaggaa ggattcttca ctttcgtcat actggcgcag ctctcgttgc
    25861 tgtaccacca gtacaccaag caactggcga cgttgaataa ttggtacgcc taaaaacgcg
    25921 cggaaacgtt cttcttttac ggaggggatg tatttgaagc tggggtgctt ttgcgcatct
    25981 gcaaggttta tcggttccgc cagcctgcca accaggccga cgatcccttc atcaaacgcg
    26041 agcgttacag tgcgaccgcg tggttttttc agcccccggg tcgccatcag gtagtaacaa
    26101 cgtcgatcat gatcggccag gtagaccgaa cagacctcgg tatccatcgc aagacagatg
    26161 tcggtaacca gaatatttaa cgcctcattc aggcgtggtg cgctggctac cttttcgact
    26221 atttcgcgca ggcgagtgag cataattggc gtgacttaac ctcttttacg tcgataagca
    26281 gatgcgtttt gtggttttgg cgtattttcc tgcagtgaca tcaccacact cgcgaactct
    26341 ttcattaccc tacggtagac atcacgttta aatgacacca cctgtctgac tggataccag
    26401 taacttaccc atcgccagcc gtcaaactct ggtgtactgc tggtttgcat attgatttct
    26461 gcatcgccgc tcaccagctg caagagaaac catttttgtt tttggccgat acaaaccggc
    26521 ttcgtgtccc aacgcaccaa acgtttcggt aatttgtagc gcaaccagtt acgcgttgaa
    26581 gcaaggattc gaacgtcttt gcggcttaat cctacttctt caaacaattc acggtacatc
    26641 gcctgctctg cggattctcc ggggttgatt ccgccttgcg gaaattgcca ggagtgctga
    26701 ccaaatcgcc gggcccacat tacctgcccc tggcgattac aaatcacgat acctacgttt
    26761 gggcggtagc catcgtcatc aatcaccgga ctacctcaaa ataaagcttt atatacgaat
    26821 gattgtttca tactccagga agacggtaaa ccactctctg cagggcatta cacactaata
    26881 acaattgaat aactcacagt tatgtgcaga gttataaaca gaggaagggg tggatagccg
    26941 tttttattca ccttttctgt ggatagagtt gtgaagaact acggaattac tacgggaaaa
    27001 cccggagcat tctgaataag cccgatatag acattttaaa atattcatta tcagtcaatg
    27061 cattacatgt aatttgagta ataaaaaaga gtaattcgtg acccaggtca cacctctcat
    27121 ttacgggttg gcgaaaaatc aatcaatgcg gtatttatcc acagaatgtg ccactaagtt
    27181 aagcactgag ccactaaaaa ctggagtttc gtcgcacgtc aaggctgtaa atggaaacag
    27241 tagtggaggt ttttcacagt tatcccagct ttctgtggat aacatggtgt aagatcctgt
    27301 ttattttcag tgaccagatt tggaaaaccc gttgcagtgt tgcgcaactc gattaccgac
    27361 aatctaaaaa gcaatataaa tcagataatt gaacaacgca tgtggaaaaa gttacactgc
    27421 gaatattcgg cacagaaatg ctgtttgttt tttaaccaag gtatcatgac atgtcccaac
    27481 ctcgcccact gctctctcct cccgaaactg aagaacaatt gttagcgcaa gcacaacaac
    27541 tttctggtta tacattggga gaactggcgg cacttgctgg gctggtgacg ccggagaatt
    27601 taaaacgcga taagggctgg attggcgtgt tactggagat ctggctaggt gccagcgcag
    27661 ggagtaaacc tgagcaagat tttgctgccc tgggcgtgga acttaaaact atccctgtgg
    27721 atagtcttgg tcgtccgctg gaaacaacat tcgtttgtgt tgccccgtta acgggtaata
    27781 gcggggtgac ttgggaaacc agccacgtac gccacaagct caaacgcgta ctgtggatac
    27841 cggttgaagg agagcgcagc atcccgctgg cgcagcgtcg cgtaggatca ccgttactgt
    27901 ggagcccgaa tgaagaggaa gaccgacagc tacgcgaaga ctgggaagaa ttaatggata
    27961 tgattgttct cggtcaggtt gagcggatta ccgctcgtca cggggagtat ttacagatac
    28021 gaccgaaagc agcgaatgcg aaagcgctga ccgaagccat tggtgcccgg ggcgaacgga
    28081 ttctgacgct gccgcgcgga ttttatttga agaagaattt caccagtgcg ctactggccc
    28141 gtcattttct gatccagtag ccatcgcttt gacctgccgc tttccgggca tataattacc
    28201 gcttcatttt tttggcaggg ctttttagat gttatttgca tggataaccg atcctaacgc
    28261 ctggcttgcg ctcggtacgc tgacgctgct ggagatcgtt cttgggatcg acaatattat
    28321 tttcctttct ctggtggtgg caaagctccc cacagcacaa cgtgctcatg cgcggcgtct
    28381 ggggttggcg ggagccatgg ttatgcgtct ggcgctgctg gcatcaatcg cctgggttac
    28441 gcgcctgaca aatccgcttt ttacattatt cagtcaggaa atttccgccc gtgatttgat
    28501 tctgcttctg ggtggcttgt tccttatctg gaaagccagc aaggaaatcc acgaatccat
    28561 tgaaggtgaa gaagaagggc tgaaaacacg cgtttcatca ttcctcggcg ctatcgtgca
    28621 gattatgctg ctggatatta tcttcagcct cgactcggtg attaccgctg tgggtctgtc
    28681 agatcacctg tttattatga tggcagccgt ggtgattgcc gtaggcgtta tgatgtttgc
    28741 cgcgcgctcg attggtgatt ttgtcgaacg ccatccttcg gtaaaaatgc tggcgctctc
    28801 tttcctgatt ctggtgggct ttaccctgat tctggaaagt ttcgacatcc acgtaccgaa
    28861 aggttacatc tacttcgcga tgttcttctc tattgcggtt gaaagcctca acctgattcg
    28921 caacaaaaag aacccgctct gatactccgt acgctctcct gcgggagggc gtactcactc
    28981 ctgttaccct cacagtttaa gattttcctg ctttcaagat atataacgtc ggtttataaa
    29041 cagactatta tcataggtgg gccaaatgag gataaccgga tgaaaaaatg ggcagtaata
    29101 atttctgcag tcggactggc gtttgctgtt tccgggtgtt ccagtgatta cgtcatggcg
    29161 accaaagatg gccgtatgat tttgaccgat ggaaaacctg aaattgatga tgataccggg
    29221 ctggtgagtt atcacgatca gcaaggtaac gcgatgcaaa ttaaccgtga tgatgtttcg
    29281 caaattattg aacgttaaca aataaggtca gcatccggct ggccttaaga tttttctctt
    29341 tcccttttcc cttccctctg ccatttttat attccttatg tcgtgattat aaaaaggaaa
    29401 cggctatgca atatcaccgt ataccccaca gttcgctgga agtcagcacg ctggggcttg
    29461 gcacgatgac gtttggtgaa cagaacagcg aagccgacgc ccacgcacaa ctcgactatg
    29521 ccgtcgctca gggcattaac cttatcgacg ttgccgaaat gtacccagta cctccgcgcc
    29581 ccgaaacgca agggttaacc gaaacctacg tcggcaactg gctggcgaaa catggcagcc
    29641 gcgaaaagtt aattatcgcc tccaaagtga gcggaccgtc gcgcaataat gacaagggca
    29701 tccgcccgga tcaggcgctg gatcggaaga atatccgcga agcgttgcat gacagcctca
    29761 agcgtctgca gactgattac ctcgatcttt atcaggtgca ctggccgcag cgcccaacca
    29821 actgctttgg caaactcggt tatagctgga cggattctgc gcctgcagtt tcgctgctgg
    29881 atacgctgga cgcactggca gagtaccaac gcgcgggaaa aattcgttat atcggcgtgt
    29941 cgaacgaaac tgcatttggc gtaatgcgct acctgcatct ggcagacaaa cacgatctgc
    30001 cgcgtattgt caccattcag aacccttaca gtctgttaaa ccgcagtttt gaagtaggtc
    30061 tggcagaagt cagccagtat gaaggggtcg aactgctggc ctattcgtgc ctgggtttcg
    30121 gcacgctgac cgggaaatat ctcaacggtg caaaacccgc tggcgcacgt aatacgctct
    30181 ttagtcgctt cacacgctat agcggtgagc aaacgcaaaa agccgtcgcg gcgtatgttg
    30241 atatagccag acgtcatggc ctggatcctg cacagatggc gctcgctttt gtacgccgtc
    30301 aaccgtttgt tgccagcact ctgctgggcg caaccacgat ggagcagctg aaaactaacg
    30361 tcgaaagttt gcatctggag ttaagcgaag acgtattagc tgaaattgaa gcggtacatc
    30421 aggtttatac ttatccggca ccataagatt aacgccgatt aaaaccggcg ttaaatatta
    30481 atgacggcgc tgccagatcc acagcgccgt tattgccagc gcaaacagcg caccgaagcc
    30541 aatgccaatg ggcacgaccg ggatgcctac cattaccgcc agcgagtaaa tgcccagcat
    30601 caacaacatg gcgctgtttt cgccaaggtt ttgtactgca attgcattcc ccgccccgac
    30661 gcttttttta ccccgttcct gtagcaacgc attgagcgga acgacaaaaa agccccccag
    30721 cacgccaatc agcatcaaca aggcataggc tggcagcagc tcgtgttgca gggagaaaat
    30781 cagtaccacc acgccaatca aaatcccggc tggcatacag cgtgacacgg tttccagcgt
    30841 aactaacttc gctgccgcac cagcgccaac cacgatacca atcgctacca tcgcgttgag
    30901 ataggtcggc gtagcgttat cggtaatgcc cagcgccacc ggtacccaca gcaccaacag
    30961 gaaacgcagc gtgacacctg ctccccagaa taaactggtg cccaccagcg aaaaacgcgt
    31021 ttcaccattg cgccatagcg aggtgcaggc attcaggaaa ctgcgggtca tgttgatgag
    31081 attccaggac tgccccggac gcgccgccgc cagtttggga atgtagatat tggcaacgac
    31141 cgcaccaccg taggccagtg cgcatgcggc cagggcgacc aggacatgcc agtcagccag
    31201 tacaccaccg gctacggaac cgagcaaaat cgccgctatg gtagaagctt ccattaaacc
    31261 gttagctttc actaacttac tacccgtggt taattcgccg agaataccgt atttcgccgg
    31321 tgaataggct gcagcaccaa cacccaccag cgtatagccg agaaacggat tgataccaaa
    31381 gcagatactg gctgcgccca gcagcttcag gccgttggca aacatcatca cccggccttt
    31441 ggcgaagcta tccgccacct gcccgacaaa cggcgcaaaa agaatgtaag cacctacaaa
    31501 caccatttgc aggatgggct ggctccactc cggatagaac tgcgctttca gtagcgctag
    31561 agtggcaaac agtagtgcat tatcgccaaa cgcagagaga aactgcgcca cgataaccgc
    31621 tttcatcccc ttcgaccaca acgaagtgtt agtgtgcact gactcactca tcgtgttgtt
    31681 ccgcttcgtc tacccagctt ttcaacgtga caaagtcagg tttgccgctg ccaagtaatg
    31741 gcatctgttt cagatagcga atatcgcgcg gtacagcaag ctccggcacg ccgtgctcgc
    31801 gggcatactg ttgcaactta tcgcgcgtca gttcgttatc tgtggtgaaa agcaccagcg
    31861 cctcgccttt gctggcatcg ctcttaatcg cagtggcatg gactttatct ggcgaaacac
    31921 caagtgccag ttgttccacc atttccagcg ataccatttc gcctgcaatt ttggcaaagc
    31981 gttttgcgcg gccctgaatc tgcacaaagc cctgctcgtc gaaacgcaca atatcgccag
    32041 tgtcatacca gccgcgctcc atttcgccgc gaacattctc ggcggtgggc acttccagta
    32101 cacctggctt ctccacccgc agatagccgt tcattatgtt cggccctttc agttgcaggc
    32161 gtccgccctc ttcgatacca ggaaccgaca acaggcgcgc atccattcct ggtagaatac
    32221 gccctaccgt accgggtttc gccgccatcg gtacgttgat ggaaacgaca ggcgcgcact
    32281 cggtcacacc gtagccttca aggatccgca ggccaaattt atcctgccaa agctgtttgg
    32341 tactttcttg tagtttttct gcgcctgcca ccacatagcg tagacggtag aagtcatacg
    32401 ggttggcgaa acgcgcgtag tgaccgagga aagtggaggt accgaacaac acggtgcaac
    32461 tgcggtcata caccaactcc ggcacaatac ggtaatgcag cgggcttgga taaaggaaca
    32521 cttctgcacc tgtgagcagt ggcgtaaaca ggcctaccgt cagcccaaag gagtgaaaca
    32581 gcggtaacgc cgacataaag cgatcgttgg tggtgaagtc ggcaatcgtt ttaatctgct
    32641 cgacgttcgc cagaatgctt ttatggctat ggacgacgcc tttcggatgg ccttcagaac
    32701 cggaggtaaa aaggatcagc gcctcttctt ccggctgctg ttttacctgt gccagacgcg
    32761 gcatcagcaa atgagcgaag atccacactt tgtcggcagt ggtgacatct gcttttaaat
    32821 cttccagata gacccagcgc acctgagtaa gttgctccgg cagatgccag agtttgcctt
    32881 tatcgagaaa ctggcgggaa gtgaagatgg ttttgatttc agccgccgta atagcactgg
    32941 tcagcccttt taccccggcg gtgtagttca tcattgcggg aatgcggcga cgggcgatgg
    33001 ccccaaaaat cactgccgca ctgatgcctg cattgggcag cattaagccg atgtgttcgc
    33061 cttcaacact gtatttttca aggatgcgtc caacaaacag cgttttcgta agcaatttgc
    33121 gataggagtc tggggtaaag ttgacgtctt cgacacattt cttcccggct ccgaagcggt
    33181 acattgcact cagtaaagat tcgtacagcg tttcacgcgg gcgcaccgcc atacgcgctt
    33241 ccatcattat ttgatgcagc atttcgccag cgattttgcg acggtcacgg gcacgcggcg
    33301 catccggcat ctctacctgc gttggtggca aaatatgcag agtaatttgc gggaacaagc
    33361 gacgtttaac caggcctttc aggcggctga agtgcgtaag ttccgcccct tcaatacgca
    33421 caggaataac cgttgcacca gacttcgccg cgacaaaacc cgcaccatcg tagattttca
    33481 tcagcgagcc tgtggtggtg attcgtcctt cagggaaaat caccactggt cggccctgtt
    33541 ccaccagacg taccagatgt ttaatcgcca taggttgcgt cgggtcgaga ggaacaaagt
    33601 cgataaatga tttcagccaa cgcatatacc actgttggct tattgaggtg taaacggcaa
    33661 ataccggacg tacgggtaaa aacaatgcca gcagtatgcc atcaataaaa gagacgtgat
    33721 taggcgtgat tagaacgcgc tcgcccttca gtgcctgggt gtcacccgta acgcgaacgc
    33781 gatacaaaac acggcacaaa tttcgaaaaa agctaaaaag cattccaact ccctttgctc
    33841 tgattcagta aaagcgaatg gagggagatt acacgagata aagaacgcga gcgacagtaa
    33901 attaggtgcg aaaaaaaacc tgcgcatccg cgcaggttgg tgcaagagac agggtacgaa
    33961 gagcgtaccg aataatctca ccaatcaata cctctgggat cttgattgtg gtctgcacga
    34021 cgactcttcg ccagcgagaa aacgcaaagg aatgaaggga aatgcaacga ggtgtgtaaa
    34081 ttgtcggtta ctgttacaga ttgatgaccg gcaaaaaaaa acctgcgcat ctgcgcaggc
    34141 tggtgtaatt catgtgctca acccgaagtt gacttcacct atcaatacct ctgggatcac
    34201 cactttagca acctgaagcc aaacgccacc agcggtcaat cgcaacagcg tttcgcaaag
    34261 tgtaaccaaa ggtttgcaat ctcttttttt gtcttactta tttgcgtttg gctcacattc
    34321 ccacgatgaa aacacgccac cccttgaacc aacgggcgtt ttccgtaaca ctgaaagaat
    34381 gtaagcgttt acccactaag gtattttcat ggcgaccata aaggatgtag cccgactggc
    34441 aggcgtttca gtcgccaccg tttcccgcgt cattaataat tcacccaaag ccagcgaagc
    34501 ttcacggctt gctgtgcata gtgcaatgga gtctcttagc tatcacccga acgccaacgc
    34561 ccgtgcgctg gcgcagcaga ccactgaaac ggtcggtctg gtcgttggtg atgtttccga
    34621 tccgtttttc ggtgcaatgg tgaaagcggt cgaacaggtg gcttatcaca ctggtaattt
    34681 tttattgatt ggcaacggtt accacaacga acaaaaagag cgtcaggcta ttgagcaact
    34741 gatccgccat cgctgtgctg cgttggtcgt ccatgccaaa atgataccgg atgccgattt
    34801 agcctcatta atgaaacaaa tgcccggtat ggtgctgatc aaccgtatcc tgcctggctt
    34861 tgaaaaccgt tgtattgctc tggacgatcg ttacggtgcc tggctggcaa cgcgtcattt
    34921 aattcagcaa ggtcataccc gcattggtta tctgtgttct aaccactcta tttctgacgc
    34981 cgaagatcgt ctgcaagggt attacgatgc ccttgctgaa agtggtattg cggccaatga
    35041 ccggctggtg acatttggcg aaccagacga aagcggcggc gaacaggcaa tgaccgagct
    35101 tttgggacga ggcagaaatt tcactgcggt agcctgttat aacgattcaa tggcggcggg
    35161 tgcgatgggc gttctcaatg ataatggtat tgatgtaccg ggtgagattt cgttaattgg
    35221 ctttgatgat gtgctggtgt cacgctatgt gcgtccgcgc ctgaccaccg tgcgttaccc
    35281 aatcgtgacg atggcgacgc aggctgccga actggctttg gcactggcgg ataatcgccc
    35341 tctcccggaa atcactaatg tctttagtcc gacgctggta cgtcgccatt cagtgtcaac
    35401 tccgtcgctg gaggcaagtc atcatgcaac cagcgactaa ccgcagttaa agcaattcca
    35461 gtgccagtaa ttcttcgatg gtctggcgac ggcgaattaa ccgcgcctga ccattatcaa
    35521 acagaacttc tggtaacagc ggacggctat tgtagttgga tgacattgac gcgccatatg
    35581 cccccgtatc atgcagtacc agataatccc ctgccttcac ttccggcaag gcgcgggttt
    35641 caacatttcc cccttcctgc tgggtaaaga catcgcccga ttcacataac ggcccggcga
    35701 cgacggtttc caccgttggt gcgtgttcca gtgaacgacc atcagctgcc agggcactga
    35761 tatggtggta actaccgtac attgccggac gcatcagatc gttgaacccg gcatcaacca
    35821 gcacaaagtg gcggctaccc atttgtttga cgctccgcac ctgagtaatt aacacgccag
    35881 actgcgctac caggaagcga cccggttcaa tttccagttt cacagggtgg cccaaatggc
    35941 gggcgatttg ctcacgcgcg gcattccaca gaccataata atgttcggta tcaaccgcct
    36001 cttcaccctg ttgataagga atagaaagcc caccgcccgc agaaatagcc tgtaaatcct
    36061 gaccgaattc gaggacctga cgcaccatag caccacatac ctgttccaga tgggcataat
    36121 caacgccaga accaatgtgc atgtgaatgc cgaccagctg tagatgatga cgttgtatca
    36181 cgtccagtgc ggcgggcaga tcggtgtacc agataccgtg cttgctgttt tcgccaccag
    36241 tattggtttt ttggctatgc ccgtgaccaa accccggatt aacacgcagc catacccgat
    36301 gccctggcga aacctgaccc agttggtcga gcatatcaac agaacccgca ttcaccggaa
    36361 tttgcaattc actgacgcgt tcaagcgtcg cctgatcgat aacatctgcc gtaaaaacaa
    36421 tatcatcggg gtacgtttgc ggattgtaac ccgccgccaa cgcacgctct atttcgccta
    36481 acgagacgga atccactttc acgccctgct cacgcattaa gcgcaaaata tgaatattgg
    36541 aacaggcttt ctgtgcgaag cgcaccacat caaactgttt cagcgctgca atctgccgac
    36601 gaataatttg cgcatcgtag acccacaccg ggcagccaaa ttctgcgggc aaacgcagca
    36661 gattttcggc ggtgagatcg gtatcagtgc tgaacagtga atgtggcata acaaactcca
    36721 gataagtgct tttttatgat tacgccacat cataaaaaga ataaaaaata tcgatttatg
    36781 ttgagtctat gcaaaaatga tatggattac cggattgcga gagagcgcta atggccgccg
    36841 ttaacttacg tcatattgaa atttttcatg cggtaatgac cgccggaagc ctgactgagg
    36901 cggcacacct gctacacacc tcacagccaa ctgtcagccg cgaactggcg cgctttgaga
    36961 aggtgatcgg gctgaaattg tttgagcgcg tacgtggacg attgcatcct accgtgcaag
    37021 gactgcgtct gtttgaagaa gtgcaacgat cctggtacgg actggatcgc attgtcagcg
    37081 ccgcagaaag tctgcgcgag tttcgccagg gagaactgtc tattgcctgc ctgccggtct
    37141 tttcgcaatc ttttttaccg cagctcctgc aaccctttct ggcacgttat cccgatgtca
    37201 gcttaaatat cgtgccccag gaatcaccgc tacttgaaga gtggctctcg gcccagcgtc
    37261 atgatttagg actcactgag acactccata cgcctgcggg aacagaacgt accgaattac
    37321 tctctttaga tgaagtgtgt gtgttacctc cgggtcatcc gctggcggca aaagagatat
    37381 taacgccaga agattttcac agtgagaact acatcagcct ttcccgtact gacagctatc
    37441 gccagttgct ggatcaattg tttactgaac atcaggttaa acgacgcatg atcgtagaaa
    37501 cccacagcgc cgcgtcagtc tgcgcaatgg tacgggcggg ggtaggtgtt tcggtggtta
    37561 acccgctcac cgcactggat tatgcggcaa gcggtttagt ggtgcggcgg ttcagtattg
    37621 cggttccgtt caccgtcagc ctgatccgcc ccctgcaccg cccgtcatca gcgctggtgc
    37681 aggcgtttag tgagcattta caagcgggat taccgaaact ggtcacttct cttgacgcta
    37741 ttttgtcgtc agctacgaca gcataaaagc gacagcatcc tcggcatgga tcgccgcggt
    37801 atcaaacaca ggcagaacac tgcgctcttc tggcaccagt aaaccaattt ctgtgcagcc
    37861 aaaaataacg ccctgtgcgc cctgttctgc aaggcgagca atcacttgcg cataataagt
    37921 gcgtgacgct tcggtaaatt gccccagaca cagttcttca aaaataatct gattaatttt
    37981 cgcccgttca tccgcttcag gaatgagaca gttgatggaa aattgttccg tcagccgccc
    38041 gcgataaaaa tcctgttcca tggtgtaacg cgtacccagc agcgccacac gagtcattcc
    38101 agcccggata attgcacgtc cagtggcatc cgctatgtgt aagaaaggca gagagcaacg
    38161 agactcaatg gcatccgcca ctttgtgcat cgtattggta cataacacaa taccttctgc
    38221 gcccgcccgc tgtaagccaa gcgccgcctc agccagaata tccccggttt tgtcccactc
    38281 accgcgacgc tggcactctt ctatttcatg aaaatcgacg ctatgtagca gcacttgcgc
    38341 agagtgaagc ccaccaagcc gctgtttaat accttcattt atcaaacgat agtaaggaat
    38401 ggtggattcc cagctcattc ctcccagcaa accaattgtt ttcattcctc tctcctgatg
    38461 tgtgttaccg caacaaggct gaataaggaa cgagacaaac gcctcaacgg ccaggtgccc
    38521 aatctctatt aacgaaaaaa gggctggatg tacagcacat ccggcccgtg aaatcagacg
    38581 ccgatatttc tcaacttctc gcctgccatc agtttgcgtt cgatatgttc cagcgtgaca
    38641 tttttggttt ccggaatgag ccagaaagta atgcccacaa acgcaatgtt cagcccagtg
    38701 tagagccaga acgtaccggc agcgccaatg ctatcaagca gtgtcaggaa ggtcgcgccg
    38761 ataatcatat tcgacaccca gtttgtcgtc gttgagcagg tgatgccaaa atcgcggcat
    38821 ttcagcggct gaatttcaga gcacaagatc cacaccactg gcgcggcgct catcgcataa
    38881 ccggcaatac acatcatcgt catgccaaca gagagccagg acaagccact ggaagccgta
    38941 ccgttatcaa actgcatcag gcagtaaccc agcaccagag tgcctaacgc catcacgctg
    39001 aaaccaattt tcagagccgg tttacgccct gctttatcta ccgtaaagac cgcaatgaag
    39061 gtggcgaaca taaaggtcag ccccacgacc agagtcgcaa tcatctgctg ttctgtggtc
    39121 gtaaagcccg ccattttgaa gatacgcggc gcgtagtaca tgatgatgtt cataccggta
    39181 aactgctgca tcgcctgcaa caacataccg agaaacacag cacgacggac gttacggttg
    39241 atcttaaaca gtgcccaacc gccctgtttt aacttcaggc tttcacgaat ttcgttgagt
    39301 tcttctcgcg ctttttccga cgtatcacgc agcatacgca acacttcttc cgcctcaata
    39361 tgacgcccct tttccgccag ccagcgcggg ctatttggca ggaagaccac cagaataatc
    39421 agcaggactg ccggtaaggc aagaaccccc aacattgcgc gccagttacc gctataactg
    39481 aacgctgtat cggataaaaa cgccagcacg atgccgagag tgaccatcaa ctggtacatg
    39541 ctgatcatct taccgcgaac gttttcactt gccatttcag aaagatacag aggagcggtg
    39601 taagacgcga tcccgacagc aatgcccagc accacacgag ctgcgattaa catctctacg
    39661 ctggtcgcaa aagcggaccc tatcgagccg agcacaaaca ggatggcccc cgccatcagg
    39721 ctgtatttac gccccaggcg gaacgacagc caaccattaa acagcgcacc aattgctgcg
    39781 ccgagcatca tgctactgac cacccattcc tgcaaacgac tggtcagtac aaagtgatcg
    39841 gtaatgaacg gcaacgctcc ggcgattacg ccgatatcaa gaccaaataa caatcctgcg
    39901 accgcagcag ctaccgaaac aaacatattc atacgccgcg tatcccgcaa agaacgtggc
    39961 gttaaagtag attccgtatt gatagtaacc attttttcct gccagcagag agtaagacat
    40021 agtgaaaaaa tacgtgaaca attcacacag gtgtcaggtc ggaaatagca taaatatgga
    40081 ttaaattgct acgacatgtc gttatgtgat ggatattcca attttcaaat taagttgaat
    40141 aattgagatt attattaacc acctaatttt aaagcagata aaactcataa agttcattaa
    40201 ttgataattg atatggatta tttcataacc atgatatgga ttatgatgat ctacaggtat
    40261 aaaaaaccct gccatgcggc agggtcataa aagtaagaga aatgaattaa cgagccagcc
    40321 aaccgccatc cacggcaatg gtataaccat tcacataatc tgaagcgctg gaggcaagga
    40381 acactaccgg ccccatcagg tcactcggca gtccccaacg gccagctgga atgcggtcga
    40441 gaatttccgc gctacgttgt tcatctgccc gtagttgttg agtattgttg gttgccatgt
    40501 aacccggagc tatcgcatta acattaatgt tgtgtttagc ccattcattc gccatcaatc
    40561 gcgtcacgcc catcacgccg ctttttgatg cggtataaga aggcacacgg atcccgccct
    40621 ggaaggagag cattgacgcg atattgataa tcttgccgcc attgccttgc gcgataaagt
    40681 gtttcgccgc tgcctgagac atgaagaata cgctcttgat attcaggttc atgacatcgt
    40741 cccagtcttt ttcgctgaac tcgagagcat cttcgcgccg aatcaatccg gcgttattca
    40801 ccaggatatc aatatgacca aactcagcta ccgcgcgatc cagcagtgct ggaatgccat
    40861 caatctttcg cagatcggcg gtcaggctta aaaaacgacg ccccagcgcc gtgacctgct
    40921 tgatggtttc agtcggttca acgatgttaa tgccaacaat gtcacagccc gcttgcgcca
    40981 gccccaacgc catcccctga cccagtccag tatcacaacc agtgacgacc gcaactttac
    41041 cttcgagaga aaatgcactt aaaatcataa caatacctta ttcgtttatg cccacaacta
    41101 gcgcaaatct ttaacggcca catggtccat atcatcaaag acctggtttt caccgaccat
    41161 gccccagata aaggtataag ctttggttcc gacaccggaa tggatcgacc agctcgggga
    41221 gatcaccgcc tgctcgttat gcatcacaat atgacgcgtt tcttgcggct gccccatcat
    41281 gtggaaaacg caggcgtcat catccatatt gaaatagaaa taaacttcca tccggcgctc
    41341 gtgggtgtga cacggcatgg tgttccacaa gttacccgga gccagctccg tcagccccat
    41401 actcaattgg caggtttcca gtacatccgg gacaaaatat ttgttaatcg tgcgacggtt
    41461 actggtgagg ttatcgccta acgtgactgg agatacttcg tccggtgtga cttttttggt
    41521 gggatacgtc gtatgcgcag gtgcgcaatt gtaataaaac ttcgccggag tggcggtatc
    41581 aatactggca aagacaactt cttttgcacc tttaccaaca tacagggcgt cgcggtgacc
    41641 gatttcatag cattgaccat cgacagtaat cgtaccggca ccgccaatat tgataacacc
    41701 taactcgcga cgttccagga aatagcttac gccgagttgt ttaccaactt ccccgccaac
    41761 ggaaaccgtt ttagttaccg gcataatgcc gccaacaata atacggtcaa tgtggctgta
    41821 aaccatggtg tactcatcgg cgataaatac cttttcaacc aaaaattcat tgcgcagccc
    41881 ctgggtatcc agcgtttttg catgcgcact gtggatgctc tgtcttacgt ccacatcaac
    41941 ctccgataat cagtgaagcg tgaaaataga aaacgatagt gaaacactgt ttcgttttct
    42001 ctataagggg atgatatgcc cacgggatag ggttttcaat taaaaataaa acattgtttc
    42061 atttttaagt taaggactga aaaaagtgca gtgtcgatca cgaatatgtc atgagaatgg
    42121 gaaaatcagg gagccctgaa aatgtatgtc gactcgccag ccaccattat tcaacagatt
    42181 aatgacggct gatatttatc ggtaaggagg aaatgcagag ctattcgtca cgttcaatgg
    42241 tcaatgccac gccctggccc ccgccgatac aaagcgtagc cagtcctttg cgggcattac
    42301 gtttcaccat ttcatgaacc agagacacga ggattcggca accggaagcg cctattgggt
    42361 gaccgagtgc gatcgcgcca ccattgacat tgacccgacg ctcatcccat tcaagcatct
    42421 tgccaaccga aagcgcctgt gcagcaaacg cttcattagc ctcgataaga tcgacatcag
    42481 ccaactgcca gccaacacgc tccaggcaac ggcgggtcgc atacaccggc gcaattccca
    42541 tcaatgccgg atctacacca acgctggcaa atgcgcggat gcgggccagc acgggtaaat
    42601 tcaacgctcg tgctttggct tcgctcatca tcattactgc agctgcgcca tcgtttatgg
    42661 atgatgcatt acccgctgtc acagagccga gactatcaaa tgaaggattt aaacgggcta
    42721 agccttctgc actggcgtca gtgcgtggct gttcatcggt atctacaacc aacgtctgac
    42781 cgttactttg ggtcattacc gggacgatct catctttaaa tcgtccggcg tcaatcgccg
    42841 ctcgcgcttt ttgttgcgag ctaagtgcgt aagcatcctg caactgacgg ctgatgccat
    42901 attcgcgagc cagattttcg gcggtgacac caatatgata atcattgaag gcatcccaca
    42961 acccatcgtg cacaagacta tcaaccaact ggctattacc aagctgtgca ccggtgcggc
    43021 tatcagtcag aacatgtggt gcgcgactca tgttttcctg accaccggcg atgacaatat
    43081 cagcctcgcc acactgtatc gcctgagtag ccagatgcag tgctttaagc ccggaaccgc
    43141 aaacgtcatt aatcgtgatt gcagaaacgc tattaggaag accaccttta atagccgatt
    43201 gccttgccgg attctgccct gcccctgcag tcaacacctg accaagaatc acttcatcca
    43261 ccgcatatgc agaaacaccg gtacgttcta ttaacgcttt cacgaccagg ctgccaagtt
    43321 ccacagcgga atgacccgct aacgcaccac gaaagcagcc gataggtgtc cgtaacgccc
    43381 cgacaatcac aacgtctttc atcacaacct cgcaccaatt aacagtgcaa tagtaaatga
    43441 ttgttaattg cagttatctt aattgtttaa aaaaagtgat ttttatcaca aaggaaatat
    43501 gcctgagtag cagtcagaga cataactggc acgtaaggtt tgcaaccact aacccaccaa
    43561 tagagaggta gaaagggcgt taatctccca tacttaacct ggtttatggt aaattgccct
    43621 ccattttgtt taatttgtag atgatacgtt cagataatgt ctaatatttg gtcaaaagaa
    43681 gaaactctgt ggagtttcgc gctctacggc acagccgttg gtgcaggcac gctcttcctt
    43741 cctattcagt taggttcggc aggggctgtg gtcctgttta ttactgctct ggtcgcctgg
    43801 cctttaacat attggccaca taaagcctta tgccagttca tcctctcatc aaaaacatca
    43861 gcaggtgaag ggataacggg cgcagtaaca cactactatg gcaagaagat tggtaatctg
    43921 attaccacgc tgtacttcat cgcctttttt gtcgtcgtgt tgatatatgc cgtggcaatt
    43981 accaactcac ttacggaaca gctggcaaag catatggtta ttgatcttcg tatccgtatg
    44041 ttggtgagtc tgggtgttgt attaatcctg aatctcattt ttctgatggg acgccatgcc
    44101 actattcggg taatgggatt tttggtattc ccattgattg cctatttctt atttctttct
    44161 atttacctgg tcggtagttg gcaacctgat ctattaacta cccaggtaga gttcaatcag
    44221 aatacccttc accagatatg gatatcgatt cccgtgatgg ttttcgcctt tagccatacg
    44281 cccattattt ctacgtttgc catagacaga cgtgaaaaat atggcgaaca cgctatggat
    44341 aaatgcaaaa aaattatgaa agtcgcttat ctcatcatct gcataagtgt actgttcttt
    44401 gtctttagct gcctgctttc tattccacct tcgtatattg aagcggctaa agaagaaggg
    44461 gttaccattt tatcggcact ttctatgctg ccgaacgccc cagcatggtt gtcaatttcc
    44521 gggattattg tcgcagtagt tgcgatgtcg aaatcattcc tgggtacgta ctttggcgtt
    44581 attgaaggtg ccacagaggt cgtcaaaaca acattacagc aggttggtgt aaagaaaagt
    44641 cgtgcattta accgcgcact atcaattatg ttggtatcgc tgattacctt cattgtttgt
    44701 tgcattaacc cgaacgcgat ttcgatgatt tacgcgatca gcggcccgct cattgccatg
    44761 atactgttca tcatgcctac gctgtcaaca tatctcatcc cggcgcttaa accctggcgt
    44821 tccgtcggaa atctgattac gctgatcgtg ggtatcctgt gcgtatcggt aatgttcttt
    44881 agctaatatc cattgtgaat ggttcaaaat tgctacaatt ttgaaccatt ccagttttca
    44941 taatgttcat ttgttataat tccgctctat cacttctctc gtcatatcct agtattatca
    45001 gttagttaaa cacacaaaga gatctgaaca tcttaaataa gactatttaa gatgcataac
    45061 ttagattcgc aagatatctt ctggtcattc aaaaacaatt tgcgatatag atattctcat
    45121 accatgagat agttatctga accaccatca accaggtaag attaaatcag taaaacataa
    45181 tcatatttaa taacgagaaa tgcattttta aatgctttac tcagaattat agcaaattca
    45241 gattaatcgc aatttttccc agcaaattta caaaatcatg gtgtattgac atcatcaata
    45301 accaatgaaa ttatgcaatt atatacggat agggaggttc ttaacatggg gctttgtagt
    45361 cgttataaaa gtcttacatg caatagttgc tcaatgcatt gccaaataat gccagaagag
    45421 tcaccgcgtt tgcagtattg cgcaaactcg tgtttttgta tgtggcccga agaaagttca
    45481 tattttaatc gtggtgtggt ggaaggtatt ttaacaaaaa accacaatgc gagattaagc
    45541 ggatatattt ttgtcgattt ttcagtaagt tttttacgtc tattccttga aaaagactgg
    45601 attgactatc ttgcaagtac tgacatgggg attgttttag tcagcgaccg caatatgcaa
    45661 tcgttagcta actactggcg aaaacacaac tctgcaatat ctgctgtcat atataatgat
    45721 gatggtcttg atgttgccaa tgaaaagatc agacaactat ttattggtcg ttatttatca
    45781 tttaccagag ggaacacatt aactcagatg gaattcacca taatgggata tatggtttct
    45841 ggttataatc catatcagat tgctgaagtt ctggatatgg atatccgtag catctacgcg
    45901 tacaagcaac gaatcgaaaa gagaatgggt ggtaaaataa acgagttatt tattcgttca
    45961 cattcggtcc aacattgata ctcaataatc tgccagaatc atactctgct tatacgggca
    46021 tctattgaaa tgcccgtatt ttacaaataa gcagtaaccc caagagtaaa caacatggta
    46081 tttaaaacca tcacacgaaa aattcagaag cattacgaaa tatgaattta caaacaatag
    46141 tggcataaat gttaatcatg ttaatttacg taaagtttta cgttgcgaca ttaaagcctc
    46201 atttcaatca ttatgataaa tataaaatta atatatattt atgccgtaaa tatcaatata
    46261 cttagcaaac tatgtgattt ccatttcgat tgatttagtg tctattgacg tatgtactgg
    46321 attattaacg ataatatcga gttctggcct gagcaccgaa aattaatatc ggtacataac
    46381 gccgatctta acgtcgttct gacaacgcca gccagtcgtt gtttatcact tctacttgaa
    46441 gcttttcctg atgtggttgc acaacaagat tttttcacca gagtctggga agaagaaggt
    46501 atgcgtgtgc caactaacac gttatatcag aacatatcca ttatcagacg cggatttcgc
    46561 gctgttggtg ataccaccca ctcgcttatt gcaaccgtgc cgagaagagg attcaagatt
    46621 cataatgaca ttaacataca aaatcatgca ataaactctt caacagacgc acatacacac
    46681 aatgccccac ctgccgtaaa aggtaatgcg gggtacaaag agagcattgg aagcgcaaac
    46741 aatttcaata acaaaatcct caaacatata aaaagttatc taattatgtt gagcatattt
    46801 gctataggcg tatattctgc acattggcta tggaataata atcaaccgaa acctttcttc
    46861 aaggattaca agactgttgc ggaaattaat ggctgccatt ttaatgtgac agaagataca
    46921 attgatgggt tgaaagagtt cgataaatat aagacacgga tactggattc ggggattaac
    46981 tgtaaaaaat atccgtggtt atacttccct cttgcaaaat cctcaccagg gatgattgtt
    47041 atggcatgca ataaaaacta taaccaacat gaagtggcag gctgtttaac cctgtcttac
    47101 cgtgaggtta atcgtgattg attataaaaa aaacttatta tttattttag tttttatcag
    47161 tg
//
LOCUS       DACAOP010000026        46237 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.026, whole genome shotgun sequence.
ACCESSION   DACAOP010000026 DACAOP010000000
VERSION     DACAOP010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46237
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.026"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(158..1000)
                     /gene="purU"
                     /locus_tag="IT892_001642"
     CDS             complement(158..1000)
                     /gene="purU"
                     /locus_tag="IT892_001642"
                     /EC_number="3.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="HAP3134871.1"
                     /translation="MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHR
                     TGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLL
                     MKANYGGLDVEIAAVIGNHDTLRSLVERFDIPFELVSHEGLTRNEHDQKMADAIDAYQ
                     PDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAH
                     YVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNR
                     TIIL"
     gene            complement(1050..1508)
                     /locus_tag="IT892_001643"
     CDS             complement(1050..1508)
                     /locus_tag="IT892_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
                     /protein_id="HAP3134872.1"
                     /translation="MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQ
                     DADYLIKTWHPSCGAAALRAELMAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTE
                     GGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ"
     gene            1621..2526
                     /gene="rssA"
                     /locus_tag="IT892_001644"
     CDS             1621..2526
                     /gene="rssA"
                     /locus_tag="IT892_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HAP3134873.1"
                     /translation="MRKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGS
                     LVGAAYACDRLSALEDWVTSFSYWDVLRLMDLSWQRGGLLRGERVFNQYREIMPETEI
                     ENCSRRFAAVATNLSTGRELWFTEGDLHLAIRASCSIPGLMAPVAHNGYWLVDGAVVN
                     PIPISLTRALGADIVIAVDLQHDAHLMQQDLLSFNVSEENSENGDSLPWHARLKERLG
                     SITTRRAVTAPTATEIMTTSIQVLENRLKRNRMAGDPPDILIQPVCPQISTLDFHRAH
                     AAIAAGQLAVERKMDELLPLVRTNI"
     gene            2618..3631
                     /gene="rssB"
                     /locus_tag="IT892_001645"
     CDS             2618..3631
                     /gene="rssB"
                     /locus_tag="IT892_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RssB"
                     /protein_id="HAP3134874.1"
                     /translation="MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDAL
                     ELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGV
                     EDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
                     QPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALL
                     LRALFNGLLQEQLAHQNQRLPELGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLI
                     LVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLML
                     SAE"
     gene            3833..4741
                     /gene="galU"
                     /locus_tag="IT892_001646"
     CDS             3833..4741
                     /gene="galU"
                     /locus_tag="IT892_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP3134875.1"
                     /translation="MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQY
                     VVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHV
                     TIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
                     ETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRY
                     VLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAF
                     VEYGIRHNTLGTEFKAWLEEEMGIKK"
     gene            complement(4885..5298)
                     /gene="hns"
                     /locus_tag="IT892_001647"
     CDS             complement(4885..5298)
                     /gene="hns"
                     /locus_tag="IT892_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator H-NS"
                     /protein_id="HAP3134876.1"
                     /translation="MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEE
                     SAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDE
                     NGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ"
     gene            5903..6520
                     /gene="tdk"
                     /locus_tag="IT892_001648"
     CDS             5903..6520
                     /gene="tdk"
                     /locus_tag="IT892_001648"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAP3134877.1"
                     /translation="MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRF
                     GAGKVSSRIGLSSPAKLFNQNSSLFDEIRAEHEQQAIHCVLVDECQFLTRQQVYELSE
                     VVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQA
                     GRPYNEGEQVVIGGNERYVSVCRKHYKEALQVDSLTAIQERHRHD"
     gene            complement(6802..7698)
                     /locus_tag="IT892_001649"
                     /pseudo
     CDS             complement(6802..7698)
                     /locus_tag="IT892_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904641.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(7822..10497)
                     /gene="adhE"
                     /locus_tag="IT892_001650"
                     /gene_synonym="adhC"
     CDS             complement(7822..10497)
                     /gene="adhE"
                     /locus_tag="IT892_001650"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAP3134878.1"
                     /translation="MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAAD
                     ARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAE
                     PIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAA
                     GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTP
                     VVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQG
                     KELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAH
                     EKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTA
                     RILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAEN
                     MLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGV
                     ETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHF
                     EELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLAD
                     YALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLL
                     KEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLA
                     NALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKL
                     LAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQ
                     ILLDTYYGRDYVEGETAAKKEAAPAKAEKKAKKSA"
     gene            10974..11621
                     /gene="ychE"
                     /locus_tag="IT892_001651"
     CDS             10974..11621
                     /gene="ychE"
                     /locus_tag="IT892_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YchE"
                     /protein_id="HAP3134879.1"
                     /translation="MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARN
                     KTNLTANLSVAIILWISLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGED
                     KQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
                     ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN"
     gene            complement(11779..12075)
                     /locus_tag="IT892_001652"
     CDS             complement(11779..12075)
                     /locus_tag="IT892_001652"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134880.1"
                     /translation="MRFLLANTFCKIVKQFSFIDRIRIYSLHPCLNKYLSIQSNRDWL
                     SMSIFSDYSSSSEMHNNLTIDYYLALSSTKGSGITNIISIILQQAQDYDVAKIT"
     gene            12359..13990
                     /gene="oppA"
                     /locus_tag="IT892_001653"
     CDS             12359..13990
                     /gene="oppA"
                     /locus_tag="IT892_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein OppA"
                     /protein_id="HAP3134881.1"
                     /translation="MTNITKRSLVAAGVLAALMAGNVALAADVPAGVTLAEKQTLVRN
                     NGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHL
                     RKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDL
                     GVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYT
                     LKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTYNNMPI
                     ELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA
                     QGDMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYN
                     TSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT
                     SFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPV
                     YYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH"
     gene            14076..14996
                     /gene="oppB"
                     /locus_tag="IT892_001654"
     CDS             14076..14996
                     /gene="oppB"
                     /locus_tag="IT892_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppB"
                     /protein_id="HAP3134882.1"
                     /translation="MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPE
                     VMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGA
                     AAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHW
                     LPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRR
                     IILRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVL
                     SLTILVGALTILFNAIVDVLYAVIDPKIRY"
     gene            15011..15919
                     /gene="oppC"
                     /locus_tag="IT892_001655"
     CDS             15011..15919
                     /gene="oppC"
                     /locus_tag="IT892_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HAP3134883.1"
                     /translation="MMLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLI
                     VLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGR
                     ISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF
                     GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNV
                     LGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPA
                     GFLVVTLFCFNFIGDGLRDALDPKDR"
     gene            15931..16944
                     /gene="oppD"
                     /locus_tag="IT892_001656"
     CDS             15931..16944
                     /gene="oppD"
                     /locus_tag="IT892_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppD"
                     /protein_id="HAP3134884.1"
                     /translation="MSVIETATVPLAQQQADALLNVKDLRVTFSTPDGDVTAVNDLNF
                     SLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNGREILNLPEHELNKLR
                     AEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKNMSKAEAFEESVRMLDAVKMPEARK
                     RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREF
                     NTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPVHPYSIGLLNAVPRLD
                     AEGETMLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAPPLEEFTPGRLRACFKPVE
                     ELL"
     gene            16941..17945
                     /gene="oppF"
                     /locus_tag="IT892_001657"
     CDS             16941..17945
                     /gene="oppF"
                     /locus_tag="IT892_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppF"
                     /protein_id="HAP3134885.1"
                     /translation="MNAVTEGRKVLLEIADLKVHFEIKDGKQWFWQPPKTLKAVDGVT
                     LRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGHVAWLGKELLGMKPDEWRAVRSD
                     IQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKMSRQEVRERVKAMMLKVGLLPNLINR
                     YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSL
                     IFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTRALMSAVPIPDPDLE
                     KNKTIQLLEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVLEGSFRHAVSCLKVDPL
                     "
     gene            complement(17998..18327)
                     /locus_tag="IT892_001658"
     CDS             complement(17998..18327)
                     /locus_tag="IT892_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309775.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciU family protein"
                     /protein_id="HAP3134886.1"
                     /translation="MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEE
                     RGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKL
                     CHIIWRE"
     gene            complement(18362..19822)
                     /gene="cls"
                     /locus_tag="IT892_001659"
     CDS             complement(18362..19822)
                     /gene="cls"
                     /locus_tag="IT892_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP3134887.1"
                     /translation="MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLII
                     YILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAP
                     LFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
                     VAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRR
                     MDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIY
                     SCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAR
                     EYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAG
                     VKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQ
                     DDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL"
     gene            19965..20138
                     /locus_tag="IT892_001660"
     CDS             19965..20138
                     /locus_tag="IT892_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciY family protein"
                     /protein_id="HAP3134888.1"
                     /translation="MKRSRTEVGRWRMQRQASRRKSRWLEGQSRRNMRIHSIRKCILN
                     KQRNSLLFAIYNI"
     gene            complement(20193..21446)
                     /gene="kch"
                     /locus_tag="IT892_001661"
     CDS             complement(20193..21446)
                     /gene="kch"
                     /locus_tag="IT892_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated potassium channel protein"
                     /protein_id="HAP3134889.1"
                     /translation="MSHWATFKQTATNLWVTLRHDILALAVFLNGLLIFKTIYGMSVN
                     LLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIY
                     TLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALY
                     LSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMT
                     SIFGPLIRGGFNKLVKGNNHTMHRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLP
                     EDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKD
                     MSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLL
                     NSGHGIFSDNDELETKADSKESAQK"
     gene            complement(21746..22042)
                     /locus_tag="IT892_001662"
     CDS             complement(21746..22042)
                     /locus_tag="IT892_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HAP3134890.1"
                     /translation="MLYVIYAQDKADSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMP
                     AVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKVF"
     gene            22266..22985
                     /gene="tonB"
                     /locus_tag="IT892_001663"
     CDS             22266..22985
                     /gene="tonB"
                     /locus_tag="IT892_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein TonB"
                     /protein_id="HAP3134891.1"
                     /translation="MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQP
                     ISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP
                     VKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQ
                     PQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPG
                     KPGSGIVVNILFKINGTTEIQ"
     gene            complement(23025..23423)
                     /gene="yciA"
                     /locus_tag="IT892_001664"
     CDS             complement(23025..23423)
                     /gene="yciA"
                     /locus_tag="IT892_001664"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HAP3134892.1"
                     /translation="MSTTHNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAI
                     LAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVQKGTTSVSINIEVWVKKVASE
                     PIGQRYKATEALFKYVAVDPEGKPRALPVE"
     gene            complement(23528..24067)
                     /locus_tag="IT892_001665"
     CDS             complement(23528..24067)
                     /locus_tag="IT892_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HAP3134893.1"
                     /translation="MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRF
                     RKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQ
                     RMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLI
                     FTLLSGIYIYRHMPQEDKS"
     gene            complement(24097..24840)
                     /locus_tag="IT892_001666"
     CDS             complement(24097..24840)
                     /locus_tag="IT892_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0259 family protein"
                     /protein_id="HAP3134894.1"
                     /translation="MSITAQSVYRDTGNFFRNQFMTILLVSLLCAFITVVLGHVFSPS
                     DAQLAQLNDGEPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVIL
                     IIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLAL
                     APVMLVQDKMGVFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEI
                     GAVLANTLSNLISAILLIYLFRLYMLIRQ"
     gene            complement(24868..24957)
                     /locus_tag="IT892_001667"
                     /pseudo
     CDS             complement(24868..24957)
                     /locus_tag="IT892_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460692.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            25197..25835
                     /gene="ompW"
                     /locus_tag="IT892_001668"
     CDS             25197..25835
                     /gene="ompW"
                     /locus_tag="IT892_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
                     /protein_id="HAP3134895.1"
                     /translation="MKKLTVAALAVTTLLSGSAFAHEAGEFFMRAGSATVRPTEGAGG
                     TLGSLGGFSVTNNTQLGLTFTYMATDNIGVELLAATPFRHKIGTRATGDIATVHHLPP
                     TLMAQWYFGDASSKFRPYVGAGINYTTFFDNGFNDHGKEAGLSDLSLKDSWGAAGQVG
                     VDYLINRDWLVNMSVWYMDIDTTANYKLGGAQQHDSVRLDPWVFMFSAGYRF"
     gene            complement(25895..26401)
                     /locus_tag="IT892_001669"
     CDS             complement(25895..26401)
                     /locus_tag="IT892_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HAP3134896.1"
                     /translation="MNRIEHYHDWLRDAHAMEKQAESMLESMASRIDNYPELRARIEQ
                     HLSETKNQIVQLETILDRNDISRSVIKDSMSKMAALGQSIGGIFPSDEIVKGSISGYV
                     FEQFEIACYTSLLAAAKNAGDTASIPTIEAILNEEKQMADWLIQNIPQTTEKFLIRSE
                     TDGVEAKK"
     gene            complement(26447..26947)
                     /locus_tag="IT892_001670"
     CDS             complement(26447..26947)
                     /locus_tag="IT892_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HAP3134897.1"
                     /translation="MNMKTIEDVFIHLLSDTYSAEKQLTRALAKLARATSNEKLSQAF
                     HAHLEETHGQIERIDQVVESESNLKIKRMKCVAMEGLIEEANEVIESTEKNEVRDAAL
                     IAAAQKVEHYEIASYGTLATLAEQLGYRKAAKLLKETLEEEKATDIKLTDLAINNVNK
                     KAENKA"
     gene            complement(27033..27212)
                     /locus_tag="IT892_001671"
     CDS             complement(27033..27212)
                     /locus_tag="IT892_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309858.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HAP3134898.1"
                     /translation="MAEHRGGSGNFAEDREKASDAGRKGGQHSGGNFKNDPQRASEAG
                     KKGGQQSGGNKSGKS"
     gene            complement(27593..28399)
                     /gene="trpA"
                     /locus_tag="IT892_001672"
     CDS             complement(27593..28399)
                     /gene="trpA"
                     /locus_tag="IT892_001672"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HAP3134899.1"
                     /translation="MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAG
                     ADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMY
                     ANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADD
                     DLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPD
                     QVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS"
     gene            complement(28399..29592)
                     /gene="trpB"
                     /locus_tag="IT892_001673"
     CDS             complement(28399..29592)
                     /gene="trpB"
                     /locus_tag="IT892_001673"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016158396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HAP3134900.1"
                     /translation="MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQ
                     FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG
                     KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
                     SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE
                     REGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRV
                     GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALE
                     AFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK
                     ARGEI"
     gene            complement(29604..30962)
                     /gene="trpCF"
                     /locus_tag="IT892_001674"
     CDS             complement(29604..30962)
                     /gene="trpCF"
                     /locus_tag="IT892_001674"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /protein_id="HAP3134901.1"
                     /translation="MQTVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDALQ
                     GARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFNFLPI
                     VSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMGV
                     LTEVSNEEEQERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGIN
                     TYAQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAGA
                     IYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQLH
                     GNEEQLYIDTLREALPAHVAIWKALSVGETLPAREFQHVDKYVLDNGQGGSGQRFDWS
                     LLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTLR
                     AY"
     gene            complement(30966..32561)
                     /gene="trpD"
                     /locus_tag="IT892_001675"
     CDS             complement(30966..32561)
                     /gene="trpD"
                     /locus_tag="IT892_001675"
                     /EC_number="2.4.2.18"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase glutamate
                     amidotransferase component TrpG/anthranilate
                     phosphoribosyltransferase TrpD"
                     /protein_id="HAP3134902.1"
                     /translation="MADILLLDNIDSFTYNLADQLRSNGHNVVIYRNHIPAQTLIERL
                     ATMSNPVLMLSPGPGVPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAG
                     EILHGKASSIEHDGQAMFAGLTNPLPVARYHSLVGSNIPAGLTINAHFNGMVMAVRHD
                     ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPANTLQPILEKLYQAQTLSQQES
                     HQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADI
                     VGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNAD
                     KSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGV
                     YSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
                     GLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGHEDLQANA
                     QTVLEVLRSGSAYDRVTALAARG"
     gene            complement(32561..34123)
                     /gene="trpE"
                     /locus_tag="IT892_001676"
     CDS             complement(32561..34123)
                     /gene="trpE"
                     /locus_tag="IT892_001676"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HAP3134903.1"
                     /translation="MQTQKPTLELLTCEGAYRDNPTALFHQLCGDRPATLLLESADID
                     SKDDLKSLLLVDSALRITALGDTVTIQALSGNGEALLALLDNALPAGVESEQSPNCRV
                     LRFPPVSPLLDEDARLCSLSVFDAFRLLQNLLNVPKEEREAMFFGGLFSYDLVAGFED
                     LPQLSAENNCPDFCFYLAETLMVIDHQKKSTRIQASLFAPNEEEKQRLTARLNELRQQ
                     LTEAAPPLPVVSVPHMRCECNQSDEEFGGVVRLLQKAIRAGEIFQVVPSRRFSLPCPS
                     PLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDATSRQIEIYPIAGTRPRGR
                     RADGSLDRDLDSRIELEMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDR
                     YSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYG
                     GAVGYFTAHGDLDTCIVIRSALVENGIATVQAGAGVVLDSVPQSEADETRNKARAVLR
                     AIATAHHAQETF"
     gene            complement(34215..34259)
                     /gene="trpL"
                     /locus_tag="IT892_001677"
     CDS             complement(34215..34259)
                     /gene="trpL"
                     /locus_tag="IT892_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon leader peptide"
                     /protein_id="HAP3134904.1"
                     /translation="MKAIFVLKGWWRTS"
     gene            34397..35278
                     /gene="yciV"
                     /locus_tag="IT892_001678"
     CDS             34397..35278
                     /gene="yciV"
                     /locus_tag="IT892_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exoribonuclease"
                     /protein_id="HAP3134905.1"
                     /translation="MSDTNYAVIYDLHSHTTASDGCLTPEALVHRAVEMRVGTLAITD
                     HDTTAAIAPAREEISRSGLALNLIPGVEISTVWENHEIHIVGLNIDITHPLMCEFLAQ
                     QTERRNQRAQLIAERLEKAQIPGALEGAQRLAQGGAVTRGHFARFLVECGKASSMADV
                     FKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYNLSAKWLKRLVAHFAE
                     HHGDAMEVAQCQQSPNERTQLAALARQHHLWASQGSDFHQPCPWIELGRKLWLPAGVE
                     GVWQLWEQPQNTTEREL"
     gene            35275..35895
                     /locus_tag="IT892_001679"
     CDS             35275..35895
                     /locus_tag="IT892_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAP3134906.1"
                     /translation="MSQFFYIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKI
                     EDKNAMERICRIRQLPDGHNFTLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILK
                     GTKEVPRRLLQEKRKTIGMRVPSNPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEI
                     KDRLEKQVDLIIHGGYLGQKPTTVIDLTDDTPVVVREGVGDVKPFL"
     gene            35923..37818
                     /locus_tag="IT892_001680"
     CDS             35923..37818
                     /locus_tag="IT892_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HAP3134907.1"
                     /translation="MAGKFRCILLLIAGLFVSSLSYAENTEIPSYEEGISLFDVEATL
                     QPDGVLDIKENIHFQARNQQIKHGFYRDLPRLWMQPDGDAALLNYHIVGVTRDGIPEP
                     WHLDWHIGLMSIVVGDKQRFLPQGDYHYQIHYQVKNAFLREGDSDLLIWNVTGNHWPF
                     EIYKTRFSLQFSNIAGNPFSEIDLFTGEEGDTYRNGRILEDGRIESRDPFYREDFTVL
                     YRWPHALLSNASAPQTTNIFSHLLLPSTSSLLIWFPCLFLVCGWLYLWKRRPQFTPVD
                     VIETDVIPPDYTPGMLRLDAKLVYDDKGFCADIVNLIVKGKIHLEDQSDKNQQILIRV
                     NEGATRNNAVLLPAEQLLLEALFRKGDKVVLTGRRNRVLRRAFLRMQKFYLPRKKSSF
                     YRSDTFLQWGGLAILAVILYGNLSPVGWAGMSLVGDMFIMICWIIPFLFCSLELLFAR
                     DDDKPCVNRVIITLFLPLICSGVAFYSLYINVGDVFFYWYMPAGYFTAVCLTGYLTGM
                     GYIFLPKFTQTGQQRYAHGEAIVNYLARKEAATHSGRRRKGETRKLDYALLGWAISAN
                     LGREWALRIAPSLSSAIRAPEIARNGVLFSLQTHLSCGANTSLLGRSYSGGGAGGGAG
                     GGGGGGW"
     gene            38029..38904
                     /gene="rluB"
                     /locus_tag="IT892_001681"
     CDS             38029..38904
                     /gene="rluB"
                     /locus_tag="IT892_001681"
                     /EC_number="5.4.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /protein_id="HAP3134908.1"
                     /translation="MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEV
                     TPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGAR
                     WIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGV
                     QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDI
                     PLPKGLPRGGWTELDLAQTNYLRELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHS
                     QVSGGRRSGGRNNNG"
     gene            complement(38944..39534)
                     /gene="cobO"
                     /locus_tag="IT892_001682"
     CDS             complement(38944..39534)
                     /gene="cobO"
                     /locus_tag="IT892_001682"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HAP3134909.1"
                     /translation="MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTA
                     AFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDT
                     AACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITG
                     RGCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY"
     gene            complement(39531..40289)
                     /locus_tag="IT892_001683"
     CDS             complement(39531..40289)
                     /locus_tag="IT892_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciK family oxidoreductase"
                     /protein_id="HAP3134910.1"
                     /translation="MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGR
                     NEEKLRQVASHINEETGRQPQWFILDLLTCTSENCQQLAQRIAVNYPRLDGVLHNAGL
                     LGDVCPMSEQNPQVWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
                     NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPA
                     DIMPLYLWLMGDDSRRKTGMTFDAQPGRKPGISQ"
     gene            40509..41558
                     /gene="sohB"
                     /locus_tag="IT892_001684"
     CDS             40509..41558
                     /gene="sohB"
                     /locus_tag="IT892_001684"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HAP3134911.1"
                     /translation="MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRV
                     NNLSEQYKEMKEELAAALMDSHQQKQWHKAQKKKHKQEAKAAKAKAKLGEVATDSKPR
                     VWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQR
                     LRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKD
                     IDIELHTAGQYKRTLTLLGENTEEGREKFREELNETHQLFKDFVKRMRPSLDIEQVAT
                     GEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKRLIDRFTGSAAESAD
                     RLLLRWWQRGQKPLM"
     gene            complement(41594..41845)
                     /locus_tag="IT892_001685"
     CDS             complement(41594..41845)
                     /locus_tag="IT892_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciN family protein"
                     /protein_id="HAP3134912.1"
                     /translation="MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLV
                     FTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYHLVD"
     gene            42225..44822
                     /gene="topA"
                     /locus_tag="IT892_001686"
     CDS             42225..44822
                     /gene="topA"
                     /locus_tag="IT892_001686"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAP3134913.1"
                     /translation="MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAA
                     KKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEK
                     ADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNID
                     RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEE
                     FWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPT
                     TSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNM
                     VRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQ
                     LIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRIL
                     PAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRG
                     YVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDH
                     FFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYAL
                     PPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHV
                     CGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTR
                     KILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVE
                     ELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYV
                     DGKWVEGKK"
     gene            45032..46006
                     /gene="cysB"
                     /locus_tag="IT892_001687"
     CDS             45032..46006
                     /gene="cysB"
                     /locus_tag="IT892_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CysB"
                     /protein_id="HAP3134914.1"
                     /translation="MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDEL
                     GIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHT
                     QARYALPNVIKGFIERYPRVSLHMHQGSPTQIADAVSKGNADFAIATEALHLYEDLVM
                     LPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTP
                     RIVFTATDADVIKTYVRLGLGVGVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRR
                     STFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEVMFKDIKLPEK"
BASE COUNT        11779 a        10954 c        11641 g        11863 t
ORIGIN      
        1 ggggtaatgc tttttactgg cctgctccct tatcgggaag cggggcgcat catatcaaat
       61 gacgcgccgc tgtaaagtgt tacgttgaga aaaatgaact ggttgcgtaa ttttcatccg
      121 taacggatta aaggtaacca gttatttttg ctggcgatta aagaataatc gttcgattac
      181 cgtaaacaaa gacgcgctgt gccagtactt tgtatagtgc acgacttaag acgtttttct
      241 cgacgtcacg acctgcgcgc atcatatctt cagctgtgta ggtatgatcg acatgaataa
      301 cgtcctgcat gatgattggg ccttcgtcca gattgtcatt cacatagtga gcggttgcgc
      361 caataatctt cacaccacgt tcataggcct ggtgataagg acgtgcgcca ataaacgctg
      421 gcaggaatga atggtgaata ttgatgatct tattcgggaa gcgtgccaca aattccggcg
      481 ttaatacccg catatacttc gccagcacca cgtagtcagg ttgataagca tcaatggcat
      541 ccgccatctt ttgatcgtgc tcgttgcggg ttaacccttc atggcttacc agctcaaacg
      601 gaatatcaaa acgctcaacc agagaacgta aagtatcgtg gttaccaata actgccgcga
      661 tttcgacatc caggccgccg taattggctt tcatcaacaa atcgccaagg caatgcgctt
      721 ctttagtgac cagaatcact atccggcgac gaccggcagg attcagctca cgcacggagc
      781 cttctggcaa tgcgctatcg agatccgcca gcagggtgga atcattaaaa atcccttcca
      841 gttccgtgcg cataaaaaag cgcccggtac ggtgatcaac aaattcattg ttctgtacga
      901 tatttaactc gtgcttgtag caaatattgg taatacgtgc gatcagacct ttttggtccg
      961 gacaaatagt acgcagaact ttacgttgga gtgaatgcat tgctggaaaa accttgttga
     1021 gagtgtttgc taaaccgtac cgtcaaccat tattggccgc agcacttttt aaatttttta
     1081 cctgaaccac aagggcaggg atcgttgcga ccaaactgcg gacgtgtacc gtcaatatag
     1141 taccattgac cgttttcttt caaaaatcgc gaacgttcaa ttattgcacc tgttttacca
     1201 ccttcggtaa atcgagcaac aaaactgaca aatccgatat tgtcggcgtc ctgccaacaa
     1261 tgttcaaata cggtcaatcc caaccattca gtatgcgcaa atccggccat caattcggca
     1321 cgtaacgccg ctgctccaca agagggatgc caggtcttta ttaaataatc tgcgtcttgc
     1381 atcacaaaag cgcagtaacg cgaacgcatg agatgttctg gatcaggtgc aaccttttca
     1441 ccagacacat aagggtggca acataggcta tactcgacag cactaccaca gggacaaagc
     1501 tgagacacaa ataatctccc tggaaacaat aacggcgtat taaccgcctg agtagcacta
     1561 tgttaaccga gaagtagcga tgtggctacg attgcattcc aggggaatct tgcgggaata
     1621 atgagaaaga taaaaatagg gctggcgctg ggatctggcg cggcgagagg ttggtcgcat
     1681 attggcgtta ttaatgcgct aaaaaaagtg ggtattgaaa ttgatatcgt tgcaggatgt
     1741 tcaattggtt cgctggtggg cgctgcctat gcatgcgatc gattatctgc gctggaagat
     1801 tgggtgacct ctttcagtta ttgggatgtt ttacgcctga tggatctctc ctggcagcgc
     1861 ggtgggttac tgcgcggcga gcgtgtcttc aatcaatacc gcgaaataat gccggaaaca
     1921 gagatcgaaa attgttcccg tcgctttgcg gctgttgcca ccaatttaag tacgggacgt
     1981 gaattatggt ttactgaagg cgatctccat cttgctattc gcgcatcatg cagtattcca
     2041 ggactcatgg cacctgttgc acataacggc tactggctgg ttgatggagc agtcgttaac
     2101 ccaattccta tttccctcac gcgtgcattg ggggctgata ttgtgatagc ggttgacctg
     2161 cagcacgatg ctcatttgat gcaacaagat ttgctctcct ttaatgtcag tgaagaaaat
     2221 agcgagaatg gtgattctct gccgtggcat gcgcgtctga aagaaaggtt aggcagcata
     2281 acgacacgtc gggcggtgac agcgccaacg gcaacagaga ttatgaccac ttctatccag
     2341 gtgctggaga accgccttaa aaggaaccgc atggcaggtg atccgcccga tattctgatt
     2401 caacctgttt gcccgcaaat atctacgctt gatttccatc gcgcgcacgc tgccattgcg
     2461 gccggacagc tggcagtgga aaggaaaatg gacgaacttt tgccgttggt acgcaccaac
     2521 atttgaccag aatttttatc tacacttaag ttaattctga caggcgcagg tggcaatagc
     2581 atgccactat tgagtaaagc cagtcagggg agagaacatg acgcagccat tggtcggaaa
     2641 acagattctc attgttgaag atgagcaggt atttcgctcg cttctggatt catggttttc
     2701 ctcattggga gcgacaacgg tactggcggc tgatggggtg gatgcccttg agttgctggg
     2761 aggtttcact ccagacctga tgatatgtga tatcgcgatg ccacgaatga acgggcttaa
     2821 actgctggag catatacgta acagaggcga ccagacccca gttctggtga tatctgccac
     2881 tgaaaatatg gcagatattg ccaaagcgtt acgtctgggc gttgaagatg ttttgctgaa
     2941 accagttaaa gatctgaatc gcttgcgcga gatggttttt gcctgtctct atcccagcat
     3001 gtttaattcg cgcgttgagg aagaggaaag gctttttcgc gactgggatg caatggttga
     3061 taaccctgcc gcagcggcga aattattaca ggaactacaa ccgccggttc agcaggtgat
     3121 ttcccattgc cgggttaatt atcgtcaatt ggttgccgcg gacaaacccg gcctggtgct
     3181 tgatattgcc gcactttcgg aaaacgatct ggcattttat tgccttgatg tcacccgagc
     3241 tggacataat ggcgtacttg ctgccttgtt attacgcgca ttgtttaacg gattattaca
     3301 ggaacagctt gcacaccaaa atcaacggtt gccagagttg ggcgcgttat tgaagcaggt
     3361 aaaccattta cttcgtcagg ccaatctgcc ggggcagttt ccgctattag ttggctatta
     3421 tcatcgcgaa ctgaaaaatc tcattctggt ttctgcgggt ctgaatgcga cgttaaatac
     3481 cggcgaacac caggtgcaaa tcagtaatgg tgttccgtta ggcactttag gtaacgctta
     3541 tttgaatcaa ttgagccagc gatgcgatgc ctggcaatgc caaatatggg gaaccggtgg
     3601 tcgactgcgc ttgatgttgt ctgcagaatg agcaaacgat aacgcgggct aaatttgcat
     3661 tacctgctaa tgtcggctgg tggtactatc gtcgccattc gtataagtaa ttgtcttaat
     3721 tatgctaact cgcctccttt tcagaactta gccccttcgg ggtgctgata tactgggatg
     3781 cgatacagaa atatgaacac gttcaaaaca cgaacagtcc aggagaattt aaatggctgc
     3841 cattaatacg aaagtcaaaa aagccgttat ccccgttgcg ggattaggaa ccaggatgtt
     3901 gccggcgacg aaagccatcc cgaaagagat gctgccactt gtcgataagc cattaattca
     3961 atacgtcgtg aatgaatgta ttgcggctgg cattactgaa attgtgctgg ttacacactc
     4021 atctaaaaac tctattgaaa accactttga taccagtttt gaactggaag caatgctgga
     4081 aaaacgtgta aaacgtcaac tgcttgatga agtgcagtct atttgtccac cgcacgtgac
     4141 tattatgcaa gttcgtcagg gtctggcgaa aggcctggga cacgcggtat tgtgtgctca
     4201 cccggtagtg ggtgatgaac cggtagctgt tattttgcct gatgttattc tggatgaata
     4261 tgaatccgat ttgtcacagg ataacctggc agagatgatc cgccgctttg atgaaacggg
     4321 tcatagccag atcatggttg aaccggttgc tgatgtgacc gcatatggcg ttgtggattg
     4381 caaaggcgtt gaattagcgc cgggtgaaag cgtaccgatg gttggtgtgg tagaaaaacc
     4441 gaaagcggat gttgcgccgt ctaatctcgc tattgtgggt cgttacgtac ttagcgcgga
     4501 tatttggccg ttgctggcaa aaacccctcc gggagctggt gatgaaattc agctcaccga
     4561 cgcaattgat atgctgatcg aaaaagaaac ggtggaagcc tatcatatga aagggaagag
     4621 ccatgactgc ggtaataaat taggttacat gcaggccttc gttgaatacg gtattcgtca
     4681 taacaccctt ggcacggaat ttaaagcctg gcttgaagaa gagatgggca ttaagaagta
     4741 acatccgtat cggtgttatc cacgaaacgg cgttgagcaa tcgacgccgt ttttttatag
     4801 cttattctta ttaaattgtc ttaaaccgga caataaaaaa tcccgccgct ggcgggattt
     4861 taagcaagtg caatctacaa aagattattg cttgatcagg aaatcgtcga gggatttacc
     4921 ttgctcatcc attgcttttt tgattacagc tggagtacgg ccttggccag tccaggtttt
     4981 agtttcgccg ttttcgtcaa cgtagctata ttttgccgga cgctgagcac gtttagcttt
     5041 ggtgccagat ttaacggcag caaggctatt cagcagttcg ttcgggtcaa taccgtcagc
     5101 gatcagcatt tcgcgatatt gctgcagttt acgagtgcgc tcttcaactt cagcagcagc
     5161 cgcgctttct tcttcgcgac gttcgttaac aacaacttct aatttttcca gcatttcttc
     5221 cagcgtttca agtgtacatt ctcttgcctg cgcacgaaga gtacggatgt tgttcagaat
     5281 tttaagtgct tcgctcattg tagtaatctc aaacttatat tggggtggtt tgttgaggta
     5341 ataatagagc cttaaattca gttgtgcaat agccaggaat gtaaggaatt caaaattgtt
     5401 ctttattttg tgccgccaat aaatatcttt tcataaaatt agccagaaaa gacgcggcat
     5461 atagccctat ttacaccgat gatttcgcag cacgtgaggt taaaacttcc tgattcatgt
     5521 cacattttat ggggagatta tcgtaggctg acgacctttc agtcttctgt attagttgtg
     5581 tttacgagaa ttccctatta agcgaatgat gaaaagtaga acagtcgcaa taagagcatg
     5641 gacttagtat tgcactatct cctggaggtc aacagagggc tattacttgc gcaacaggtt
     5701 aaagattgtg aatagttacc agcagtcatt tacccgctta taacaagcga ggcagttgta
     5761 atgatagctc agaagggtta tgcaaggctt cgtaagggag aacgcatata cccacttctg
     5821 tgcatactgt tgagctgaaa aactgacgaa ttatgataaa ctccagccaa ctttatttca
     5881 tatcattgag ggcctgtggc tgatggcaca gctatatttc tactattccg caatgaatgc
     5941 gggtaagtct acagcattgt tgcaatcttc atacaattac caggaacgcg gcatgcgcac
     6001 tgtcgtatat acggcagaaa ttgatgatcg ctttggtgcc gggaaagtca gttcgcgtat
     6061 aggtttgtca tcgcctgcaa aattatttaa ccaaaattca tcattatttg atgagattcg
     6121 tgcggaacat gaacagcagg caattcattg cgtactggtt gatgaatgcc agtttttaac
     6181 cagacaacaa gtatatgaat tatcggaggt tgtcgatcaa ctcgatatac ccgtactttg
     6241 ttatggttta cgtaccgatt ttcgaggtga attatttatt ggcagccaat acttactggc
     6301 atggtccgac aaactggttg aattaaaaac catctgtttt tgtggccgta aagcaagcat
     6361 ggtgctgcgt cttgatcaag caggcagacc ttataacgaa ggtgagcagg tggtaattgg
     6421 tggtaatgaa cgatacgttt ctgtatgccg taaacactat aaagaggcgt tacaagtcga
     6481 ctcattaacg gctattcagg aaaggcatcg ccacgattaa taagaatttc tttactgaca
     6541 gggtgagcag ggcactttta tcctgtcagt tcgttttacg cacttcttcc gggctatata
     6601 cccttctcgg cagtttttta acgccgctat acgcctcaca gggctcttaa gcaccgacgt
     6661 tgacttgtga cctgtaaagt acaatatccc tgtgtttagg cgttatacat cgtcgcaaat
     6721 atgatgaagg ctaatgctgt cggtttatgg aaaagttgct ttgggtaaac aaaaaatacg
     6781 gccccagaag ggcaatgccg ttcacttaag aggagcggca ctatgtttca caggataacg
     6841 ggtttttgat atcttaaccg acctcggcct tgatggtcgg gggcgttttg ttatgaacac
     6901 cacttccaga gcaccccgaa gatgctccag tcgtttcggg atggtccctg gtgacgccgt
     6961 gtttcccagc tctatcattt ctgatgcgat attcttccac gcaggcagta gccagtggcg
     7021 gttacaaccc ttctggttca gcgtcagcag caggtcttcg ctgtaaaaaa gtttatcaaa
     7081 caacgtaata gagttatccg ggatggtggc gagcatggag tgggccagca cagtttcgct
     7141 ctgccggtaa ggtgcggtca cggcattcag cagaatgtga cttcccaggt tcattaaggc
     7201 caccagacgc ataaccgggt aggcgttctg ccgcttagtg gatgtgttgg cagacccata
     7261 atattcacgc agctcgggtt tatcaggtgt cctgaactgt gcgccatcaa tggcaaaaag
     7321 ttgcaggccg tgccagtcat ccttcaggta acgttccgcg cccctgtctg tgcggtctgg
     7381 cggaagagcc attccactgg ggcggccccc acgcgctgac gcgcctgggt gacagcgctg
     7441 cgggccagca ggttcatccc cgcttcgcca tccgcgctca ggttcagacg gcgaacaaca
     7501 tcggtaattg gctcattgca ccaccatcca gataaccatg tcccccggta aacgacggcg
     7561 gcgaacggtc gcatgagcag aaagcgtcag gcagtgttgt atccactcgg tgggaaggtg
     7621 ttctgcaaat agttgtgcag agggcggagg cataagcgga tggtcactga aatcgagcag
     7681 atcattgaga agtggcataa gaaaacggct ccctgttgtg gaagccgtta tagtgcctca
     7741 gtttaaggat cggtcaacta atccttaact gatcggcatt gcccagaagg ggccgtttat
     7801 gttgccagac agcgctactg attaagcgga ttttttcgct tttttctcag ctttagccgg
     7861 agcagcttct ttcttcgctg cagtttcacc ttctacataa tcacgaccgt agtaggtatc
     7921 cagcagaatc tgtttcagct cggagatcag cgggtaacgc gggttagcgc cggtgcactg
     7981 gtcatcgaat gcatcttcag acagtttatc cacgttcgcc aggaagtctg cttcctgaac
     8041 gccagcttca cggatagatt tcggaatacc cagttcagct ttcagcgttt ccagccatgc
     8101 cagcagtttc tcgatcttag cagcagtacg gtcgcccggt gcgctcagac ccaagtggtc
     8161 ggcaatttca gcataacgac ggcgagcctg cggacggtca tactggctga atgcagtctg
     8221 cttggtcggg ttgtcgttcg cattgtagcg aataacgtta caaatcagca gggcgtttgc
     8281 cagaccgtgc ggaatatgga actgggaacc cagtttgtgc gccattgagt gacatacacc
     8341 caggaaggcg ttcgcaaacg cgatacccgc gatagtcgct gcactgtgaa cacgttcacg
     8401 cgctaccgga tttttagacc cttcgtggta ggacgctggc agatattctt tcagcagttt
     8461 cagtgcctgc agagcctgac catcagagaa ctcagatgcc agtacagaaa cataagcttc
     8521 catggcgtga gttactgcgt ccagaccacc gaaagcacac agggacttcg gcatgtccat
     8581 aaccaggttg gcgtcgacaa tcgccatatc cggagtcagc gcatagtctg ccagcggata
     8641 tttctgacca gtagcgtcgt cagttacaac cgcaaacgga gtgacttcag aacctgtacc
     8701 agaagtggtg gtgacagcga tcattttcgc tttcacgccc attttcggga acttgtagat
     8761 acgtttacgg atatccataa agcgcagcgc cagctcttcg aagtgagttt ccggatgttc
     8821 gtacataacc cacatgatct tcgcggcgtc catcggggaa ccaccaccca gcgcgataat
     8881 cacgtctggt ttgaaggagt ttgccagttc tgcaccttta cgaacgatgc tcagggtcgg
     8941 gtccgcttct acttcgaaga agacttcagt ttcaacgcct gctgctttca gtacggaagt
     9001 gatctgatca gcataaccat tgttgaacag gaagcggtca gtcacgatga gcgcacgttt
     9061 gtggccatca gtaatcactt catccagcgc gattggcagg gagccacggc ggaagtagat
     9121 agatttcgga agtttgtgcc acaacatgtt ttcagctcgc ttagcaacgg ttttcttgtt
     9181 gatcaggtgt ttcggaccaa cgttttcaga gatggagtta ccaccccaag aaccacaacc
     9241 cagagtcagg gaaggtgcga gtttgaagtt atacaggtca ccgataccac cctgagacgc
     9301 tggggtgtta atcaggatac gcgccgtttt cattttctga ccgaagtaag aaacgcgagc
     9361 cggttggtta tcctggtcag tgtacaggca agaggtatga ccgataccgc ccatagcaac
     9421 cagtttctct gctttttcta ccgcgtcttc gaaatcttta gcgcggtaca ttgccagagt
     9481 cggggacagt ttttcatgtg cgaacggttc gctttcatca acaacggtca cttcaccgat
     9541 cagaatcttg gtgttttctg gtacagagaa gcctgccagt tcagcaattt tataggctgg
     9601 ctgaccaacg atagccgcgt tcagcgcacc gtttttcagg ataacatcct gaacagcttt
     9661 cagctcttta ccctgcaaca gatagccgcc gtgggttgca aaacgttcac gtacagcgtc
     9721 ataaacagag tcaacaacaa caacagactg ttcagaagca cagattacgc cgttgtcgaa
     9781 ggttttggac atcagtacag atgcaactgc acgtttgata tcagcagttt catcgataac
     9841 aactggagtg ttgcccgcgc ctacaccgat agctggttta ccggagctgt atgcggcttt
     9901 aaccatgccc ggaccaccag tcgcgaggat caggttgatg tctgggtggt gcatcagtgc
     9961 gttagacagt tcaacagaag gttgatcgat ccagccgatc agatctttcg gagcaccggc
    10021 agcgatagca gcctgcagaa cgatatcagc cgctttgttg gtggcatctt ttgcacgcgg
    10081 gtgcggggag aagataatgg cgttacgggt cttcagactg atcagcgatt tgaagatagc
    10141 agttgaagtc gggttagtgg tcggaacgat accgcaaata ataccgattg gttcagcgat
    10201 agtgatggta ccaaaagtgt cgtcttcaga cagaacacca caggtttttt catctttata
    10261 ggcgttgtag atatattcag aagcaaagtg gtttttgatc actttatctt cgacgatacc
    10321 catgccggat tcggcaacgg ccattttcgc gagtgggatt cgagcatctg cagcagccag
    10381 agcggcggcg cggaagattt tgtctacttg ctcttgagtg aaactggcat attcacgctg
    10441 ggcttttttt acacgctcta cgagtgcgtt aagttcagcg acattagtaa cagccataat
    10501 gctctcctga taatgttaaa cttttttagt aaatcatctg ctcgaatacg agagtatagt
    10561 cagtgcggtg atgatttgct taacctatga aaatcaaaag cttactcgcg ctcacactca
    10621 ctgtgattta ctaaaagagt ttaaacatta gagttattat ctctaatgcg tcacttccag
    10681 gtggcgtaag caagattact cacttctggg tactgattac gtgatccaaa tcaaattttt
    10741 gcaaagctga cacctttcag catcgctttt cgccattata gctaacagtt aataaattgt
    10801 agtatgattt ggtggctaca ttagcatgtt ttgcacaact agataacaat aacgaatgat
    10861 agcaatttta agtagttagg aggtgaaaaa tgctgtcaaa aggcgtattg tcagcgcgtc
    10921 ttttcaacct tatttatggc taacattatc cggcttttgc ttcggagcta accgtgattc
    10981 agaccttttt tgattttccc gtttacttca aatttttcat cgggttattt gcgctggtca
    11041 acccggtagg gattattccc gtctttatca gcatgaccag ttatcagaca gcggcagcgc
    11101 gaaacaaaac taaccttaca gccaacctgt ctgtggccat tatcttgtgg atctcgcttt
    11161 ttctcggcga cacgattcta caactttttg gtatatcaat tgattcgttc cgtatcgccg
    11221 ggggtatcct ggtggtgaca atagcgatgt cgatgatcag cggcaagctt ggcgaggata
    11281 aacagaacaa gcaagaaaaa tcagaaaccg cggtacgtga aagcattggt gtggtgccac
    11341 tggcgttgcc gttgatggcg gggccagggg cgatcagttc taccatcgtc tggggtacgc
    11401 gttatcacag cattagctat ctgtttggtt tctttgtggc tattgcattg ttcgctttat
    11461 gttgttgggg attgttccgc atggcaccgt ggctggtacg ggttttacgc cagaccggca
    11521 tcaacgtgat tacgcgtatt atggggctat tgctgatggc attggggatt gaatttatcg
    11581 ttactggtat taaggggatt ttccccggcc tgcttaatta attcctttca aatgaaacgg
    11641 agctgccatg ctccgtttac ttcgtcatta tttttacttt gttcccgcgc agttatcaaa
    11701 agcaaaagga ataggtaaaa atattcttct caaattacag ttagttataa ggatttcctt
    11761 aactgcttct cctcaccatc atgttatttt cgccacatca taatcctggg cttgctgaag
    11821 aataattgaa atgatattag taattccact gcctttggta gaggaaagtg ctaaataata
    11881 atcaattgtt aaattattgt gcatttcact actggaactg taatcagaaa agatagacat
    11941 gcttagccaa tctctatttg attgaattga aagatatttg ttaaggcatg gatgcaagct
    12001 atagattctg atacggtcaa taaaagagaa ttgcttaaca attttgcaaa atgtattggc
    12061 gagtaagaac cgcatttggt actttccggg caaccgccag acgattcttt attggtaatg
    12121 agaataatta acaattaaag agcgtcgcga aagaataatg tgtctcgaca ggggagacac
    12181 agtacgaatc gacataaggt gatcgtctga atcaccagaa taaataaagt cggtgatagt
    12241 aatacgtaac gataaagtaa cctgacagca gaaagtctcc gagcctgtgc agggtcccaa
    12301 tccgggatta cacatgctgg ttaataccag taattataat gagggagtcc aaaaaacaat
    12361 gaccaacatc accaagagaa gtttagtagc agctggcgtt ctggctgcgc taatggcagg
    12421 gaatgtcgcg ctggcagctg atgtacccgc aggcgtcaca ctggcggaaa aacaaacact
    12481 ggtacgtaac aatggttcag aagttcagtc attagatccg cacaaaattg aaggtgttcc
    12541 ggagtctaat atcagccgag acctgtttga aggcttactg gtcagcgatc ttgacggtca
    12601 tccagcacct ggcgtcgctg aatcctggga taataaagac gcgaaagtct ggaccttcca
    12661 tttgcgtaaa gatgcgaaat ggtctgatgg cacgccagtc acagcacaag actttgtgta
    12721 tagctggcaa cgttctgttg atccgaacac tgcttctccg tatgccagtt atctgcaata
    12781 tgggcatatc gccggtattg atgaaattct tgaagggaaa aaaccgatta ccgatctcgg
    12841 cgtgaaagct attgatgatc acacattaga agtcacctta agtgaacccg ttccgtactt
    12901 ctataaatta cttgttcacc catcaacttc accggtgcca aaagccgcta tcgagaaatt
    12961 cggcgaaaaa tggacccagc ctggtaatat cgtcaccaac ggtgcctata ccttaaaaga
    13021 ttgggtcgta aacgaacgaa tcgttcttga acgcagcccg acctactgga acaacgcgaa
    13081 aaccgttatt aaccaggtaa cctatttgcc tattgcttct gaagttaccg atgtcaaccg
    13141 ctaccgtagt ggtgaaatcg acatgacgta taacaacatg ccgatcgaat tgttccagaa
    13201 gctgaaaaaa gagatcccgg acgaagttca cgttgatcca tacctgtgca cttactatta
    13261 cgaaattaac aaccagaaac cgccattcaa cgatgtgcgt gtgcgtaccg cactgaaact
    13321 aggtatggac cgcgatatca ttgttaataa agtgaaagcg cagggcgaca tgcccgccta
    13381 tggttacact ccaccgtata ctgatggcgc aaaattgact cagccagaat ggtttggctg
    13441 gagccaggaa aaacgtaacg aagaagcgaa aaaactgctg gctgaagcgg gttataccgc
    13501 agacaaaccg ttgaccatca acctgttgta taacacctcc gatctgcata aaaagctggc
    13561 gattgctgcc tcttcattgt ggaagaaaaa cattggtgta aacgtcaaac tggttaacca
    13621 ggagtggaaa acgttcctcg acacccgtca ccagggtact tttgatgtgg cccgtgcagg
    13681 ctggtgtgct gactacaacg aaccaacttc cttcctgaac accatgcttt cgaacagctc
    13741 gatgaatacc gcgcattata agagcccggc ctttgacagc attatggcgg aaacgctgaa
    13801 agtgactgac gaggcgcagc gcacagctct gtacactaaa gcagaacaac agctggataa
    13861 ggattcggcc attgttcctg tttattacta cgtgaatgcg cgtctggtga aaccgtgggt
    13921 tggtggctat accggcaaag atccgctgga taatacctat acccggaata tgtacattgt
    13981 gaagcactaa tggcaatacg tggggcagga gtgtcctgct ccacggtgtc tgatttttat
    14041 cgcattacag aaggcacagg ccagaaggta gggcaatgtt aaaatttatt ctacgtcgct
    14101 gtctggaagc gattccgacg ctatttattc ttattactat ttcgttcttt atgatgcgcc
    14161 tcgcgccggg aagccctttt accggcgaac gtactttacc gccagaagtg atggccaata
    14221 tcgaagcgaa atatcatctt aatgatccga tcatgacaca gtatttcagc tacctgaaac
    14281 aactggcgca cggtgatttc ggtccatcgt ttaaatataa agattattcg gtcaatgact
    14341 tggttgcatc cagttttccc gtttctgcca aactgggagc cgcagcattt ttccttgcgg
    14401 taatactggg tgttagtgct ggcgttattg ccgcattaaa acaaaacacc aaatgggact
    14461 ataccgtgat ggggctggca atgaccgggg ttgttatccc cagttttgtg gttgcaccat
    14521 tattagtcat gatatttgcg atcattttgc attggctgcc gggcggtggc tggaatggtg
    14581 gggcgcttaa attcatgata ttgccgatgg tggcgttgtc actcgcttat atcgccagta
    14641 ttgcgcgtat tacccgtggc tctatgattg aagtattaca ctccaatttt attcgtactg
    14701 cccgggcgaa agggttacct atgcggcgga tcattttacg tcacgcatta aaacctgctc
    14761 tgttacccgt gctctcttat atgggccccg catttgtcgg cattattacc ggttctatgg
    14821 ttatcgaaac catttatggt ttgccgggga ttggacaact gttcgttaat ggcgcattga
    14881 accgtgacta ttccttagtg ttaagcctga ccatcctggt tggtgcttta accattttgt
    14941 ttaatgccat tgtcgatgtg ctatatgcgg ttatcgaccc gaaaatccgt tactgatact
    15001 ggagctcgcg atgatgttaa gtaagaaaaa cagcgagacg ctggaaaatt tcagtgaaaa
    15061 gctggaggtc gaagggcgca gcttgtggca ggacgcacgt cgacgtttta tgcataaccg
    15121 tgcggcggtt gccagtctga tagtgctggt gctgatcgcg ttatttgtaa tcctggcacc
    15181 gatgctttcc cagtttgcct atgacgatac tgactgggcg atgatgtcca gcgccccgga
    15241 tatggagtcc ggtcactact ttggtactga ctcatccggt cgcgacctgc ttgtgcgcgt
    15301 tgcgattggc gggcgtatct cactcatggt cggtgttgct gcggcactgg tggctgtggt
    15361 cgtcgggaca ctttatggtt cgctttccgg ttatctgggc ggtaaagtgg attcggtaat
    15421 gatgcgtctg ctggaaatcc tcaactcctt cccattcatg ttcttcgtca ttttgctggt
    15481 gacctttttc ggtcaaaaca tcctgctgat tttcgtggcg ataggcatgg tttcctggct
    15541 ggatatggct cgtattgtgc gtgggcaaac cctgagtctg aagcgcaaag agtttattga
    15601 ggcggcacaa gttggcggtg tatcgacatc gggcattgtt attcgccaca ttgtgccgaa
    15661 tgtactcggt gtggtggtgg tctacgcatc acttctggtg cccagcatga tcctctttga
    15721 atctttcctt agcttcctgg ggttgggtac gcaagagccg ttaagcagct ggggtgcatt
    15781 gctgagtgat ggcgcgaact cgatggaagt ctctccatgg ttattgttgt tcccagcggg
    15841 attcctcgtg gtgacgctgt tttgtttcaa ctttatcggc gatggcttgc gtgatgccct
    15901 cgacccgaaa gatcgttaag gagtgcagcc atgagcgtaa ttgaaactgc aactgtgccg
    15961 ctcgcacaac aacaggctga cgcactgctg aacgtgaaag atttgcgtgt cacctttagt
    16021 accccggacg gcgacgtcac ggcggtcaat gatttgaatt tttccctacg tgccggagaa
    16081 acgctgggta ttgtaggtga gtctggttcg ggtaaatcgc aaactgcatt tgcgttgatg
    16141 ggcctgttgg ctgccaacgg acgtattggc ggatcggcaa ccttcaatgg gcgtgaaatc
    16201 ctcaatttgc cagagcatga actcaataaa ctgcgcgctg aacaaatctc aatgattttt
    16261 caggacccaa tgacttcgtt gaatccctat atgcgcgtcg gtgagcagtt gatggaagtg
    16321 ctgatgctgc ataagaacat gagcaaagct gaggcgtttg aagagtcggt gcggatgctc
    16381 gatgcggtaa aaatgccgga agcgcgtaaa cgcatgaaaa tgtacccgca cgaattttct
    16441 ggcggcatgc gtcagcgagt catgattgcg atggccttgt tatgtcgacc taagctgctg
    16501 attgcggatg aaccaacaac tgcgctggac gtcaccgtac aggcgcagat catgacgcta
    16561 ttaaatgaac tgaagcggga atttaatacc gccatcatta tgatcaccca cgatcttggc
    16621 gtggtggcgg ggatctgcga caaagtgctg gtaatgtacg ccgggcgcac gatggaatat
    16681 ggcaacgcgc gcgatgtctt ttatcaaccc gttcatcctt attctatcgg tttgctcaac
    16741 gcggtgccgc gtctcgatgc ggaaggtgaa acaatgttga ccatcccggg taatccgcca
    16801 aacctgctgc gattaccgaa aggttgcccg ttccagccac gttgtccgca tgcgatggaa
    16861 atttgtagta gcgcaccgcc gctggaagag tttacgcctg gccgtctgcg tgcttgcttt
    16921 aaaccggtgg aggaactgtt atgaatgctg taactgaagg aagaaaagtc ctccttgaaa
    16981 tcgccgatct taaagtgcac tttgaaatca aagatggcaa acagtggttc tggcaaccgc
    17041 cgaaaacgct caaagccgtc gatggtgtca ctcttcgcct gtatgaaggg gaaacattag
    17101 gtgtggtagg ggaatcggga tgcggtaagt ccacctttgc tcgcgccatc atcggtttgg
    17161 tcaaggcgac cgacggtcat gttgcctggt taggtaaaga gttgctgggc atgaaacccg
    17221 atgaatggcg tgccgttcgc agtgatattc agatgatttt ccaggatccg ttggcatcgc
    17281 taaacccgcg tatgaccatc ggcgagatca tcgctgaacc actgcgtact tatcatccga
    17341 aaatgtcacg ccaggaagtt cgcgagcgcg tgaaggcgat gatgctgaaa gtcgggttat
    17401 tgcctaacct gattaaccgc tatccgcatg agttctctgg tgggcagtgc cagcgtatcg
    17461 ggattgcgcg tgctcttatt cttgaaccga agctgattat ctgtgatgag ccggtgtcgg
    17521 cgctggacgt gtcaattcag gcacaggtgg tcaacctgct ccagcaattg caacgtgaga
    17581 tgggattgtc attaattttt atcgctcatg acctggccgt ggtaaaacac atttccgatc
    17641 gtgtgttggt gatgtatctc ggccatgcgg tagaactggg gacctatgat gaggtctacc
    17701 acaatccact acatccttac accagggcat tgatgtcggc agtccccata cctgatccgg
    17761 atctggagaa gaacaaaacc atccagttac tggaagggga attaccgtcg ccgatcaacc
    17821 cgccttccgg ttgtgttttc cgtacccgtt gcccgattgc cggtccagag tgcgccaaaa
    17881 cacgtcctgt tctggagggg agtttcagac acgccgtttc ttgcctgaaa gtcgatccgc
    17941 tttaaaaaca ataagggctg acagttgtca gccctttttc acgctaaaag cgattattta
    18001 ttcccgccag atgatatggc aaagtttgtg atctttttcg cggcataaca gaatgcgggc
    18061 aaaaacatcg ttgatttcac catcttcact gtccgccaga ccaatcacca cttcggcaaa
    18121 aaagtccggg ttcaaatcga aatcaacatg ttcctgccag tcttccgccg gatcgaataa
    18181 ctccgcgccg ccgcgctctt caaactgaag attgaacagc agaacatcag ctggatcgag
    18241 attgtcggca gccagttcga gaaaaatatc gtaggcctgt tcaagcgttt catcttcagt
    18301 caggcgattg tttagatcca tatccatagt tactacctgt ttaacctctg ttggcgacgt
    18361 tttacagcaa cggactgaag aagtaaaaca gtcgctcggc gacacgttgc cataatggac
    18421 gttttagcca taaacgggca tcgagcagac gtgaacgcga aatataatcg tcctgaacgg
    18481 cggcgaggtc agcaccaaaa cctttatcgt cgattgccag ggtaatctcg aaatttagcc
    18541 acagactacg catatcaagg ttaactgtgc caaccagact tagttcgcca tcgaccagca
    18601 cgctcttggt atgcagtaac ccgccttcaa actgataaat tttaacccca gcagccagca
    18661 gttccgtaaa gaatgcgcga ctggcccagc cgaccagcat cgagtcattt tttcgcggaa
    18721 ggataatact gacatccacc ccgcgctgcg ccgccgtgca aatcgcatga agtaaatcat
    18781 cgcttggcac aaagtagggc gtggtcatga tcaaatattc acgcgccgaa taagccgcag
    18841 tcaataatgc ctggtgaatg agatcttccg gaaagccggg gccagaagca attgtgtgaa
    18901 tggtgtgacc gctggcctgt tcaaacggca taatattgac atctggtggt ggcggcagaa
    18961 tacgttttcc ggtttcaatc tcccagtcgc aggaataaat aatccccatc gcggtggcga
    19021 tagggccttc catacgcgcc atcagatcaa tccattgccc tacgcccgca tcttgtttga
    19081 agtagcgagg atcgaccata ttcatgctgc cggtgtacgc gatgtaatta tcgatcatga
    19141 tcatcttgcg atgttggcgc aggtccatac ggcgtaaaaa cacacgcatc agattgacct
    19201 ttaaggcttc gaccacttca ataccggcat tacgcattag ctcgggccac gggctgcgga
    19261 aaaaagccac actcccggcg gagtcgagca tcaatcggca atgaatgccg cgtcgcgcag
    19321 ccgccattaa tgattcagcc acctggtccg ccatgccgcc gggctgccag atataaaaca
    19381 ccatctcaat attatggcgc gcgagctgga tgtcgcggat taacgcctgc atcacatcat
    19441 ctgactcggt catcagttgt agctgattcc ctttgacccc agcgatcccc tgacgacgct
    19501 cgcaaagctt gaataatggc gcagcgacac tgctattttc ttcggcgaag atatgcttac
    19561 aggctttaag gtcgttaagc cattttgcgg tggaaggcca catcgctctg gcgcgctcag
    19621 cgcggcgttt gcctaaatgg agctcgccaa cggcaagata ggcaataatt ccgactaacg
    19681 gcagaatgta aataatcaac agccaggcca tcgcggaggg aactgcgcgt cgtttcatta
    19741 gaatgcgtaa agttacgcct gcaatgagca accagtatcc cagaatggcc aaccaactca
    19801 ccaacgtata aacggttgtc atagattaga aatccttttg aaagcgcatt gttatgagtt
    19861 tacgcatatg gattcatctg gcaaataaaa acgcgggaaa agcactggtc agcgtcgggg
    19921 gtggaggtat aatgaccatt ctgttattgc atagagtagt taacatgaag cggagtagaa
    19981 cggaagtggg gcgctggcgc atgcagcgtc aggctagccg acgtaaatcg cgttggcttg
    20041 aggggcaatc gcgccgaaat atgcgtatcc acagcatcag gaagtgcatt ctaaacaaac
    20101 agcgtaactc gttattgttt gcgatctaca atatctaaat gtactgggca ccattgcggt
    20161 gcccaataag tttactcttc cgtctttaaa ctctattttt gcgccgattc tttactgtca
    20221 gctttcgttt ctagttcatc gttatcgctg aaaataccat gacctgagtt caacaacatt
    20281 gaaacgagca tatcattatt aatctcttca ccatttaaaa ctcgcgccag aatttcgctg
    20341 ccaaacagtt gcggtgagag aatgatatcc ggatgtacca tcttaatctt attcaggttt
    20401 ttgctatcac tgacggcgag aactgttttg acatcactgc tcatatcttt tgccgagagt
    20461 acaacaaacg cgttatctgc atcgttatca ctcagcgcca gaatggcccg gcaacgatcg
    20521 attcccgctt tctttaatac agaactgtca ttactgtcac cggggataac atcagcatta
    20581 tcgcctaagc gttgctcaag ttgcttgata tcatcttcag gcaagttgct gataaccgtt
    20641 acgttttgtc cgcgttgatt cagttgcagg atcgtattga tggcgagaat cgaatgtccg
    20701 caaacaataa aatgatcttt acgatgcatt gtatgattgt ttccttttac aagtttgttg
    20761 aatcccccgc ggataagcgg accaaaaatt gaggtcatag atgtggcaaa aacggtaatg
    20821 ccggaaataa tgaccgaaat agtgaacaat cgtgctgatt cagaaacagg gacaatatcg
    20881 ccatagccga cggttgacat ggtttctatc gaaaaataga acgcggtcat caaactttct
    20941 attcgcggat taaaaccttc gcttaaataa agcgcaccgt aggttgagta aaacagtaat
    21001 gtcgtgaaac taataaatgc aaaaattgtc ccggctgcgg cgctactgtg ggagaagtct
    21061 ttgcgcagta tcagcaaaaa caccagcgta aaaatgcaaa atccaatact aaatttcagc
    21121 cagggataaa aatgcagggt gtaaattagc gctatcaaca acaaaatgat actgattgcc
    21181 catgcgagct ttgcccggaa cagtaagcca atggagttca ggacaagaaa gacgccgagc
    21241 ataaagagtg gggcgtttgc cagcaaggag agatccaact ctgaaaatgc tttgatatgg
    21301 aaaatatcaa gcaaattgac cgacatacca tagattgttt taaaaataag caatccattt
    21361 aaaaagacgg ccagcgcgag aatgtcgtgc cgaagggtca cccataaatt tgttgctgtt
    21421 tgtttgaatg tagcccagtg actcactgat acctctgtaa ccacaatttt gtttaattat
    21481 cttagcgtgc acattttctg aacatacatg cagcgcgtga atgtgttaaa caatagtaga
    21541 tgactttatc cgcagtaatc aaaggatttg agcgagcaac tgtacctcag gaaaggtcat
    21601 ttttcctgaa tatgctcaca tcatataaag aaatacagat aaagttatta tctgcttgtg
    21661 gtggtgaatg cactgaccgg ctataaggaa aggccaaaca agaacacggt tgcaaaaacc
    21721 gtgcccttaa atattgaatc tctattcaga acactttctt aaatggtttc actgaaacgt
    21781 gttcatagac tcctgccgct acgtacgggt cagcatcggc ccaggcctga gctgcttcca
    21841 gcgattcaaa ttcagcaata acggttgagc cagtaaatcc cgcagcccct ggatcgttac
    21901 tgtctaccgc tggcattgga ccagctgtca acaaacgacc ttcatcatgc agtaactgta
    21961 aacgtgctaa atgtgccgga cgaacggaaa ggcgtttttc gaggctatca gctttgtctt
    22021 gagcgtaaat aacatacaac acgggcacaa ctccttgttc gggaaagttg taaagtacgt
    22081 tatttgaaag ggcgaagatc tgcaacggaa agatgatgtc tttgttaagg ccatgcataa
    22141 agtaagggta attacgccaa aaatgacatt ttcactgatc ctgatcgtct tgccttattg
    22201 aatatgattg ctatttgcat ttaaaatcga gacctggttt ttctactgaa atgattatga
    22261 cttcaatgac ccttgattta cctcgccgct tcccctggcc gacgttactt tcggtctgca
    22321 ttcatggtgc tgttgtggcg ggtctgctct atacctcggt acatcaggtt attgaactac
    22381 ctgcgcctgc gcagccgatt tctgtcacga tggttacgcc tgctgatctc gaaccgccac
    22441 aagccgttca gccgccaccg gagccggtgg tagagccaga accggaacct gagccgatcc
    22501 ccgaaccgcc aaaagaagca ccggtggtca ttgaaaagcc gaagccgaaa cctaagccaa
    22561 aaccgaagcc ggtgaaaaag gtacaggagc agccaaaacg cgatgtcaaa cccgtagagt
    22621 cgcgtccggc atcaccgttt gaaaatacgg caccggcacg cctgacatca agtacagcaa
    22681 cggctgcaac cagcaagccg gttaccagtg tggcttcagg accacgcgca ttaagccgta
    22741 atcagccgca gtatccggca cgagcacagg cattgcgcat tgaagggcag gttaaagtta
    22801 aatttgacgt tacgccggat ggtcgcgtgg ataacgtaca aatcctctca gccaagcctg
    22861 cgaacatgtt tgagcgtgag gtgaaaaatg cgatgcgcag atggcgttat gagccgggta
    22921 agccaggcag tgggattgtg gtgaatatcc tgtttaaaat taacggcacc accgaaattc
    22981 agtaagcaga aagtcaaaag cctccgaccg gaggcttttg actattactc aacaggtaag
    23041 gcgcgaggtt ttccttcagg atcaaccgcg acatacttaa ataatgcttc tgtcgcttta
    23101 tagcgttgcc caattggttc agacgctact tttttcaccc acacttcaat attaatgctg
    23161 accgatgtcg tccctttctg gacacagcgt gcatagcagc acaccacatc gccgaccgca
    23221 accggccgta agaaagtcat tccttcaacc cgcacagtca ctacgcgacc gtgggcaatt
    23281 tcttttgcca gaatagcgcc gccaatatcc atttgtgaca ttaaccaacc accaaagatg
    23341 tcaccattgg cattggtatc ggcgggcatg gctaaagtac gtaaaacaag atcgccctga
    23401 gggacgttat gtgttgtaga catggtaaaa ccgacttaaa aggaaaatca caggcgcgat
    23461 gctactatga ttttcctgag gagaacagag gagatacagc gccagccccg aaggactggc
    23521 agtctggtta ggatttatct tcctgcggca tgtggcggta gatatagata ccgcttaaca
    23581 atgtgaagat taaggtaagg gcggtcaggc caaagacttt aaagttgacc caaatatttt
    23641 gcggcagcca gaatgcgatg tagatgtttg ccagaccgca aaggataaag aaaacagccc
    23701 aggccagatt cagcttcgac cataccggtt gcggcagcgt gagttcttta cccagcatcc
    23761 gctgaattag cggctttttc atcacccatt ggctgactaa cagggctccc gcaaatagag
    23821 cataaatgac tgtaaccttc catttaataa actcatcatt gtggaagaac agcgtcaagc
    23881 caccgaagac gaccaccaga acaaaagtga tcagggccat cttctcaacc ttacgaaagc
    23941 gaacccagct atagataagc acaatcgccg tggcgacgat cagcgccgca gtagccgcat
    24001 agatgtcata aatcttgtaa aacgcgaaaa agacaaccag cggtaaaaaa tcaagaaact
    24061 gcttcatttt acgattccgt aatcaaatgc ttaaggttat tggcgaatca acatatacag
    24121 gcggaacaga tagatgagca atatggctga aatcaggttg ctcaaggtgt tcgccagtac
    24181 ggcaccaatt tccggggtta atgcggcaaa agaagaggca aaaagcagca acagtgtttt
    24241 tgccagcaac cagctcagta ctgcgggtgc caccagacgc atattcgccc aagtcagccg
    24301 catactgcta cgcatcgagg caaaaacgcc cattttgtcc tgtaccaaca tcaccggtgc
    24361 cagggccagt aaaatggcca tgataattcc cggaacgacc accagcatga tgccaatctg
    24421 tactaaaagg gtagtcagaa aaatcagaat aaataacttt ggcaatatcg gcgcactggc
    24481 accaatagct cgcagcgcac tgactctctg acccgcagac accagctgga taattaatat
    24541 tacgcctccg gcgagaatgg cgttaccgat taatcctgaa aaagtggacg ccgctgaagc
    24601 ctgcagcaaa atttgttgct gttccggtga catattctga accaggtcga acaacccact
    24661 actgccgcta acgggctcgc cgtcattgag ctgcgcaagc tgtgcatcac tgggtgagaa
    24721 aacatgccct aacaccactg tgataaacgc acatagcaac gataccaaca gaatggtcat
    24781 aaattgatta cggaagaaat ttccggtgtc acggtatacg gactgcgccg tgatagacat
    24841 gcactctcct tgagttttat gcaggtgtta attagcgggc aattgtaccc tggttaagcc
    24901 tcgggtggca gcatcaggtc ttgtatggaa aagcatatct ttgtaaagcg gaggtaattg
    24961 ctggccttca ggcatgggca aatcgcggca agtggcgacc gagttaatat ttgcgtagcg
    25021 aaaatattta aaaattgatt taaatcacat taaccaggat tctcaatgca acttctaaat
    25081 taatccagat caataaaggg tgaattatca tatgtaatgt gatctatgta ggatcatttg
    25141 ttactccaat gtaggtatat tcgtcacgtt tttataacca taacgacgga gcggatatga
    25201 aaaagttaac agtggcggct ttggcagtaa caactcttct ctctggcagt gcctttgcgc
    25261 atgaagcagg cgaatttttt atgcgtgcag gttctgcaac cgtacgtcca acagaaggtg
    25321 ctggtggtac gttaggaagt ctgggtggat tcagcgtgac caataacacg caactgggcc
    25381 ttacgtttac ttatatggcg accgacaaca ttggtgtgga attactggca gcgacgccgt
    25441 tccgccataa aatcggcacc cgggcgaccg gcgatattgc aaccgttcat catctgccac
    25501 caacactgat ggcgcagtgg tattttggtg atgccagcag caaattccgt ccttacgttg
    25561 gggcaggtat taactacacc accttctttg ataatggatt taacgatcat ggcaaagagg
    25621 cagggctttc cgatctcagt ctgaaagatt cctggggagc tgccgggcag gtgggggttg
    25681 attatctgat taaccgtgac tggttggtta acatgtcagt gtggtacatg gatatcgata
    25741 ccaccgccaa ttataagctg ggcggtgcac agcaacacga tagcgtacgc ctcgatccgt
    25801 gggtgtttat gttctcagca ggatatcgtt tttaattccg cacaaaaacg accccgtaat
    25861 atacggggtc aataaggaca tggtataaag ggtattattt cttcgcttct acgccatcag
    25921 tttcagagcg aattaaaaat ttctcagttg tttgcggaat attctgaatc agccagtcgg
    25981 ccatttgctt ttcctcattt aaaatcgctt cgatggttgg aattgaagct gtatcaccgg
    26041 cattttttgc tgctgctaat agtgaggtgt aacaggcgat ttcaaattgc tcgaagacat
    26101 atccgctaat agagcctttg actatttcat cagaagggaa tataccaccg attgactgcc
    26161 caagcgcagc cattttactc atggaatctt taatgactga acgtgaaatg tcattacgat
    26221 caagaatagt ttccagttga acaatctggt ttttggtttc actaagatgt tgttcaatac
    26281 gagcgcgtag ttcaggataa ttatctatac ggctggccat ggattcaagc atagattcgg
    26341 cttgcttttc cattgcgtgg gcgtcacgta accagtcatg ataatgttca atacgattca
    26401 tgaaaatgtc ctctttataa aatgactaaa agttaaaatt catatttcag gctttatttt
    26461 cggctttctt atttacgtta ttaatggcca gatcagtcag tttgatgtcg gtggcctttt
    26521 cttcttccag ggtttctttc agaagcttcg ctgctttacg gtaacctaat tgttcagcta
    26581 gcgtcgctaa tgtcccgtaa ctggcaatct cataatgctc gactttctgt gctgcggcaa
    26641 tcagtgcggc atcacgcact tcgtttttct cggtactttc gatgacctca ttagcttctt
    26701 caataagacc ttccattgcc acacatttca tgcgcttaat tttcaggttc gattcggact
    26761 ccacaacttg atcaatacgt tcaatctgtc catgagtttc ctcgaggtgc gcatgaaaag
    26821 cctgacttaa tttttcattt gatgttgctc ttgcgagttt tgccagtgcc cgggttaatt
    26881 gtttttctgc gctgtaggta tctgaaagca ggtgaataaa tacatcttca atggtcttca
    26941 tattcatatt tttctccagt gaaatcactg cgagccatac ggcccgcaga tgcaattatc
    27001 tttatcagct gatattaata attaacggtg aatcaggatt tgcctgattt attaccaccg
    27061 ctttgttgac cgcctttttt acccgcttca gatgcgcgtt gcggatcatt tttaaaatta
    27121 ccgccgctat gctgaccgcc tttacggcct gcgtcggatg ccttctcacg gtcttcggcg
    27181 aaatttcctg aaccaccacg atgttcggcc atgttatttc tcccgttgcg ttgcattgtt
    27241 tcattaatat gagtgttgtg tgtcgacact cattaaaatt agtcgctaat gagaattagt
    27301 caaattaagc gcaacgagaa gatagaggga aaatatattt tgaggaacat tctggatata
    27361 ttaacaatta cctgaggaat aagtgactta gagaaaatta ttgattttac tggtgttatg
    27421 ttgcgggatt aatttgtttg attatattac tgttgggcgg aaaaatgacg taagttgacg
    27481 ttcgaccggg gtaagcgaaa cggtaaaaag ataaatatta aatgaattta ggatttttcc
    27541 ggcttcatta aagaaagtta aaatgccgcc agcggaactg gcggctgtgg gattaactgc
    27601 gcgtcgccgc tttcatcggt tgtacaaaaa ctttcagtgc cgccagcatt ttctctggct
    27661 cattaatatg ttgctcgatg attttaacaa tggccgaacc agaaatcgcg cccgcagctc
    27721 ctgcatcaat cgctgctttt acctgatccg gggcggaaat accaaatccc tgcaatggag
    27781 gtgcagcgtt gtactctttc agcttcgcaa ccagatgatt gaggggtaac gcggcgcggt
    27841 tttctgcgcc ggtcacgcct gctcgtgaca gcaaataggt gtaaccacga ccgtaagagg
    27901 ctatctggcg cagcaggtcg tcatcggcat ttggcgggca gatgaagata ggtgcgacat
    27961 tatgacgcaa cgcggcctgg cggaagggcg cggactcttc aactggcaca tcggcaacca
    28021 gcaccgaatc gacgccgact ttttcgcact gggcataaaa ctcatcaatg cctttgttaa
    28081 acaccagatt ggcatacatc aacaggccaa tgggaatggt cgggtgtttc tggcgaatca
    28141 gtgccagcat ttcaaaacat tgtgccggag tcacacctgc cgcaaaggcg cgcagagtgg
    28201 cgttttgaat cgtcgggcca tccgccagtg ggtcggagaa ggggatacct aactccagcg
    28261 cgtcagcacc ggcttcaatt agcgtatcga taattttcaa tgactgctca atgcccggat
    28321 caccgagcgt gacgaaagga acgaatgcgc cttctttgcg ctccttcaac tgggcaaaca
    28381 gagattcgta gcgttccatc agatttcccc tcgtgctttc aaaatatcgt gaacggtgaa
    28441 gatgtcttta tcgccgcgac cggaaaggtt aaccaccagt agctgctctt tatccgggtt
    28501 ttcgcgcatc attttcaacg catgggccag ggcgtgggag gattccagcg ccgggatgat
    28561 cccttcgtgc aggcacagcg ttttgaaggc ttcaagggct tcatcatcgg taatagacac
    28621 gtaatcagcg cgtccagtgc tgttaagata cgcgtgttgt gggccgacag acgggaaatc
    28681 cagtccggcg gagatggagt aagattcttc aatctgcccg tcttcggttt gcatcatcgg
    28741 cgctttcata ccgaaataga tacccacgcg accatgtttt agcggtgcgc cgtgctcgcc
    28801 agtttcgata ccgtgaccac ctggctccac accaatcagg ccgacgttgg tttcattgat
    28861 gaaatcagca aacatgccga tggcattcga accgccgcca acacaggcga taacggcatc
    28921 cggcaggcga ccttctcttt ccagaatctg cgctttggtt tcttcgccaa tcatccgctg
    28981 aaactcacgc acaatggtcg gataaggatg cgggccagct gcggtgccca gcatatagtg
    29041 cgcggtttcg taactaccgg accagtcgcg cagcgcctcg ttacaggcat ctttcagcgt
    29101 cgcggaaccg ctatgcaccg ggatcacttc cgcacccatt aagcgcatac gaaaaacgtt
    29161 aggcgactgg cgttcaacgt ctttggcacc catataaata cggcatttca ggccgagcag
    29221 ggcgctggca agggccgacg ccacgccatg ctgaccggca ccggtttcgg cgatgatttc
    29281 ggttttaccc atccgcttcg ccagcaacgc ctgccccagc acctggttag ttttatgcgc
    29341 gccgccgtgc agcaaatctt cacgcttgag atacagcgtg gtgttcgtcc cggctgtaat
    29401 gttctggcat ttggtcagcg cggttggacg cccggcatag tttttcagca ggtcgttgaa
    29461 ctgagcctga aattcaggat ctttttgcgc actgacaaaa gcttcttcca gctggcgcag
    29521 agcaggcatc aggatttgtg gcacgtacat gccgccaaac tcaccaaaat aggggttaag
    29581 taatgttgtc attgttcctt tccttaatat gcgcgcagcg tctggaaaac cgaggccaaa
    29641 agacgtgcgt ctttgatgcc cggttgcgac tctacagcag aattaaaatc aagtccggcg
    29701 cagccggttt gtgccgcttc cacgcagtta tctgcgccta agccccccgc cagcagaacg
    29761 ttgccaagcg attgaccatt taatagtgac cagtcaaaac gttgcccgct tccaccctgg
    29821 ccgttgtcta aaacatattt atcaacgtgc tgaaactcgc gggcgggcag ggtttcaccg
    29881 acgcttaatg ctttccagat ggcaacatgt gctggcagag cttcacgcag cgtatcgata
    29941 tacagctgtt cttcattacc atgcagttgc actgccgcca gcgataacac cttagctttg
    30001 tccaccacat cggcaatatc gtgattgcgg aacacgccaa catactgcaa cggtgccgca
    30061 gccatcactt cctgcgcctg ttcaacgttg acgcaacgcg gtgatgtcgc aacaaaaatc
    30121 aacccaccgt aaatcgcgcc cgcgtcataa gctgctttag catcttgccc acgcgtcagg
    30181 ccacatactt tattctcacc cagcaacacc cggcgcacgg cggcgtgcaa atcgtcatgg
    30241 gccatcaacg ccgaaccaat cagaaaaccg ttagcgaagt ggcttaactc gcgcacctga
    30301 gcgtaagtat tgatgccgga ttcgctgatt accgtcacgt tgtgccccag tttcggcgca
    30361 agctcgcggg tacggttgag atcaatcgac aaatcacgca gatcgcggtt gttgatgcca
    30421 acgacctttg ctcccaatgc aatggcgcgc tcctgttcct cttcattact gacttcggtc
    30481 agcaccccca tctccagact gtgagcgacg gcggcaagct ggcgatattg gtcgtcatcc
    30541 agtactgaaa gcattaataa gcaggcatcg gcctggtaat agcgcgccag atagatctgg
    30601 taagggtcga taatgaagtc tttacataaa atcggctgcg gggcgatttg gctgacgatg
    30661 gggaggaaat taaagctccc ctgaaaatat ttctcatcag tcagcaccga aattgccgaa
    30721 gcgtaatgtt tataaatggc ggcaatgcgt gctggatcga aatcatcacg gatcacgcct
    30781 tttgacggcg acgctttctt gcactccaga ataaacgccg tgcgcgcacc ctgtagcgca
    30841 tcataaaaat gtcgcgtgct cggctgaacc tcattctgaa aactggccag cggttgctgc
    30901 tgtttgcggg cttctaccca aatcgccttg tctgcgacga ttttcgctaa aacggtttgc
    30961 atcatttacc ctcgtgccgc cagtgcggtg actctgtcgt aagcggaacc actgcgcagt
    31021 acctcaagaa cggtttgcgc attggcttgc agatcttcat ggccatgcag gcgcattaac
    31081 atggcgacgt tcgcagcgac ggctgcttca tgggcggcgt cgcctttacc ttgtaacaaa
    31141 cgtgttaaaa tgtcacggtt ttcttccggt gttccgcctg ccagttgctc ctggtggtag
    31201 ggtgtcaggc caaagtcttc tgcggtgagc tgatagcttt taatttcgcc gtcatgcagt
    31261 tcggcaacga ttgtcggcgc gtgtaatgaa acttcatcca tcccgccgct gtgcaccacc
    31321 gccgcgcgtt gataccccag cacgcgcaag gtttcggcaa tcggcagcac cagttccgga
    31381 ctataaacac caattaacgc cagcggcgga tgcgccgggt taatcaatgg ccccagcaca
    31441 ttgaacaggg tgcgggtttt cagttgctgg cgaaccggca tcgcgtggcg gaatccggtg
    31501 tgatacttcg gcgcaaagag gaaacataca cctaactcat ccagcgcctg gcgcgattta
    31561 tcggcgttca tatcaagatt aataccgaac gccgccagca gatcggacga accagattta
    31621 ctggagacgc tacggttgcc gtgtttcgcc actttcagcc cacaggccgc ggcgacaaac
    31681 gcactggcgg tagaaatatt gatactgttg ctgccgtcac cgccagtacc gacgatatca
    31741 gcaaacagat aatccgggcg cgggaacggc gctgcgtttt ccagtagcgc ggttgctgcc
    31801 ccggcgatct cgttcgggtg ctcaccgcga attttcatgc tcaccagcgc cgccgccagt
    31861 tgttccggct tcagctcgcc acgcaccacc gctgaaaaca gctggtggct ttcttgttgg
    31921 ctaagcgtct gcgcctgata cagtttttcc agaatcggtt gcagcgtgtt ggctggctct
    31981 agtttctgct gcgcccaggc cagcgtttgt tccagcaggc gagcgccctg ggtggtgaga
    32041 atggattccg gatggaactg gaatccacaa acgcgatccg catcgtgacg tactgccatc
    32101 accatgccat taaaatgggc gttgatggtt aaaccggccg gaatgttact gccaaccagc
    32161 gagtgataac gcgccaccgg cagcgggttt gttaatccgg caaacatcgc ctgaccgtca
    32221 tgttcaatgc tggaggcttt accgtggaga atttcgcccg cctgaccgac atagcccccg
    32281 taagcttcga caatcgcctg atgtccgagg caaatgccaa taatgggcag cttgccacgc
    32341 aagcgggtga ggagttccgg catacaaccg gcttcgctcg gcacaccggg gccaggagaa
    32401 agcatcagca ccggattgct catggtcgcc aggcgttcaa ttaaggtttg cgccggaata
    32461 tggttgcggt aaatcaccac gttatgccca ttgctgcgca actgatctgc caggttgtac
    32521 gtaaaagagt cgatattatc gagcagcaga atgtcagcca tcagaaagtc tcctgtgcat
    32581 gatgcgcggt ggcaatagcg cgcagtacag cgcgggcttt gttacgggtt tcgtcggctt
    32641 ccgactgcgg aacagaatca aggactacac cagcacccgc ttgcacggtg gcgataccgt
    32701 tttccaccag cgccgagcgg atcacaatgc aggtgtcgag atcgccatgc gcggtgaaat
    32761 aacctaccgc gccgccgtag ctgccgcggc gacgaccttc cgcctcggca attaactgca
    32821 tagcgcgtac tttcggcgca ccgcttaacg tccccatatt catacaggcg cgataagcgt
    32881 gcagggcgtc aagatcgtga cgcagttcgc cgactacgcg agagacgagg tgcatcacat
    32941 aggaataacg gtcaactttg gtgagatcgg cgacgtagcg gctgccgggg gtgcaaatgc
    33001 gtgccagatc attacgggcg agatcaacca gcatcagatg ttcagacagc tctttatgat
    33061 cggtacgcat ttccagttca atacggctgt cgagatctct gtccagtgaa ccatcggcgc
    33121 gacgaccgcg tgggcgtgtt ccggcaatcg ggtagatctc aatctggcgg ctggtggcat
    33181 catacttgag cgagctttcc ggcgacgcgc caaatagggt gaaatcatta tcctgcataa
    33241 aaaacatgta cgggctggga ttactctttt tcagcacgta ataggccgcc agcggtgacg
    33301 ggcagggcag agagaaacgg cgagatggca ccacctggaa aatttctcca gcgcgaatcg
    33361 ctttttgcaa caaacgcact acgccaccga actcttcatc gctctgatta cattcacaac
    33421 gcatatgcgg cacggaaacc actggcagcg gcggcgcggc ttcggtcagt tgctgacgta
    33481 gttcgttcag gcgagcagtg agacgttgtt tttcttcttc attcggagca aacaggctgg
    33541 cctgaatacg ggtgcttttt ttctgatggt caatcaccat cagcgtttca gcgagataaa
    33601 aacagaaatc agggcagtta ttttccgctg acagttgcgg taaatcttca aatcccgcca
    33661 caaggtcata agagaacagg ccgccgaaga acatggcttc tcgttcttcc ttcggtacat
    33721 tcaacagatt ctgcaataaa cggaaagcgt caaaaaccga aagggagcat aagcgggcgt
    33781 cttcatccag cagtggactg acagggggga agcgcagcac acggcagttt ggtgattgtt
    33841 cactttccac acccgcaggc agggcgttat ccagtagtgc cagcagggct tcgccgttgc
    33901 cggaaagtgc ctggattgtg acagtgtcac ctaaagctgt aatgcgcagc gcactgtcta
    33961 ccagcagcag gctttttaaa tcatctttgc tgtcgatatc tgcggattcc agcagcagcg
    34021 ttgccggacg atccccacac aactggtgaa aaagcgcggt gggattgtcg cgataagcgc
    34081 cttcgcaggt tagcagttcg agagtcggtt tttgtgtttg cattgttatt ctctaatttt
    34141 gttcaaaaaa aagcccgctc attaggcggg ctgggtatct gattgcttta cgcatggtga
    34201 atacactgcc cgtttcagga agtgcgccac caacctttca gtacgaaaat tgctttcatt
    34261 gtcgataccc ttcttacgtg aacttgcgta ctagttaact agttcgatga ttaattgtca
    34321 acagctcatt tcagaatatt tgccagaacc gttatgatgt cggcgcaaaa aacattatcc
    34381 agaacgggag tgcgccttga gcgacacgaa ttatgcagtg atttacgacc tgcacagcca
    34441 taccacagct tccgatggct gcctgacgcc agaagcattg gtgcaccgtg cagtcgagat
    34501 gcgcgtcggc accctggcga tcaccgacca tgacaccaca gctgcaatcg cgccagcaag
    34561 agaggaaatt tcacgttcgg gactggcgtt gaatcttatt cccggcgtgg aaatttccac
    34621 ggtctgggaa aatcatgaaa ttcatattgt cgggctgaat attgatatta ctcatccgct
    34681 aatgtgtgag ttcctcgcgc agcagacaga acggcgcaat cagcgggcgc agctgattgc
    34741 cgaaagactt gaaaaagcgc aaatacctgg ggcgctggaa ggcgcacaac gactggcgca
    34801 gggcggcgca gtgacgcgcg gtcattttgc gcgtttcctt gttgagtgcg gcaaagccag
    34861 ttcaatggcg gatgtcttta aaaagtatct ggcgcgcggg aaaaccggat acgttccgcc
    34921 acagtggtgt acaatagaac aagctattga tgtcattcat cattctggcg gtaaggcggt
    34981 gctagctcat cctgggcggt acaatcttag tgctaaatgg ctgaaaagat tggttgcgca
    35041 ttttgccgaa caccacggtg acgcgatgga agtcgcgcag tgccagcaat cgcccaatga
    35101 acgtacccag ctggcggccc ttgcgcgtca gcatcattta tgggcatcac aaggatctga
    35161 ttttcatcag ccatgcccgt ggatcgaact gggtcgtaaa ctctggctgc ccgcaggcgt
    35221 tgaaggcgtc tggcagctat gggaacagcc gcagaacacc acagagaggg aattatgagc
    35281 cagttttttt atattcatcc tgataaccca cagcaacgtc tgatcaacca ggcggtggag
    35341 atcgtgcgta aaggcggggt gattgtttat ccaactgatt ccggctatgc gctcggctgt
    35401 aaaattgaag ataaaaacgc gatggagcgt atttgtcgta ttcgccagct gccggacggt
    35461 cacaacttta ccctgatgtg tcgcgatctt tctgaactct cgacctattc atttgttgat
    35521 aacgttgcgt ttcgtttaat gaaaaacaac acgccgggca actatacctt catcctgaag
    35581 gggacgaagg aagtgccacg ccgtctgttg caggaaaaac gcaaaaccat cggtatgcgt
    35641 gtgccttcta accctatcgc tcaggcgtta cttgaagcat tgggcgaacc gatgctttcc
    35701 acttcgctaa tgctgccagg cagcgaattt accgaatcgg acccggaaga aattaaagat
    35761 cgtctggaaa aacaggtaga tttgattatt cacggcggct atctcgggca gaaaccgaca
    35821 acggttattg atcttaccga tgatacgccg gtcgtggtgc gtgaaggcgt aggtgatgtg
    35881 aagcctttct tataacaaat tgcgttccac ggatggaaga ctatggcagg gaagtttcgc
    35941 tgcattttgc tgttgatagc agggctgttt gtatcatctc taagttatgc agaaaacacg
    36001 gagatccctt cttatgaaga agggatctcg ctctttgatg ttgaagccac tctgcaacca
    36061 gatggggtgc tcgacatcaa agaaaatatt cattttcagg cgcgaaatca gcagattaag
    36121 cacggctttt atcgtgattt accacgacta tggatgcagc ctgatgggga cgctgcactg
    36181 ctgaactatc atattgttgg cgtcacccgt gatggtattc ctgaaccctg gcatcttgac
    36241 tggcatatcg ggttaatgag tattgtcgtg ggcgataaac aacgtttctt gcctcaaggc
    36301 gactatcatt atcaaattca ttatcaggtt aaaaatgctt tcctgcgtga gggggattct
    36361 gatctgctaa tctggaacgt gaccggtaac cactggccgt ttgaaattta taagacccgt
    36421 ttttctctcc agttctctaa tattgcgggt aatccattta gcgaaatcga tctctttacc
    36481 ggagaagagg gcgacacata tcgtaatggc cgcatccttg aggacggaag aattgaatcc
    36541 cgcgatccgt tttatcgtga agatttcacg gtcctctacc gctggcctca cgctttactt
    36601 agcaatgcct cggctccgca aacgacgaat attttcagcc atcttctttt accctccacg
    36661 tcatcgttgt taatttggtt tccgtgtctg ttcctggttt gtggatggtt atatctctgg
    36721 aagcgcaggc cgcaatttac gccggtagat gtgattgaaa ccgatgtcat tccgccagat
    36781 tacacgcccg gcatgttacg tctcgatgcg aagctagttt acgacgataa aggtttttgt
    36841 gccgatatcg taaatctgat tgtgaaagga aaaattcatc tggaagatca gtctgacaag
    36901 aaccagcaaa tcctgattcg tgttaatgaa ggcgcgacca gaaataatgc ggtattactg
    36961 cccgcagagc agttattact ggaagcgtta tttcgtaaag gcgataaggt cgttcttaca
    37021 gggagacgca acagagtctt acgcagggca tttttacgga tgcagaaatt ttatctgccg
    37081 cgtaaaaagt cttcgtttta ccggtctgat acttttttgc aatggggtgg actggcaata
    37141 ttggcggtca ttctttacgg taacttgagt cctgtaggct gggcaggaat gagtctggtg
    37201 ggcgatatgt ttattatgat ctgctggatt attccttttt tattttgttc ccttgagctt
    37261 ttgtttgccc gcgatgatga caagccttgc gttaatcgtg taatcatcac tttgttttta
    37321 ccactgattt gttcaggcgt ggccttctat tctctctaca tcaatgtcgg agatgtattc
    37381 ttttactggt atatgccagc gggttatttt accgctgttt gcctgaccgg ttatctcact
    37441 ggcatggggt atatttttct gccaaagttt acccaaactg gacagcaacg ttatgcccac
    37501 ggtgaagcta tcgttaacta tcttgcgcgt aaagaggcag caacacacag tggacgtcgg
    37561 cggaaagggg aaacacggaa actggattac gcgttgctag gttgggctat atcggcaaat
    37621 ttggggaggg aatgggcgtt acgcattgcc ccttcgcttt cttcggcgat tcgcgctcca
    37681 gagattgccc gtaacggcgt tttattctca ttacagacgc acctaagttg cggggccaat
    37741 accagtttgt tggggcgaag ttattccggt ggtggtgctg gcggcggcgc gggtggcgga
    37801 ggcggtggtg gctggtaatt aagctgatgt taatcgaaac aagctttaac cataaagata
    37861 gtgtagtatg ttgcgcctca aagccaggcc gataaacgtc gagtcgttta cttaaggcct
    37921 gaagagttca aacagacttt actatcagtg agtcagatgt aagttctgac tcactgttgc
    37981 acaaaagcat atcagacgcc tgggaaggcg acaccaaaag gaagctctat gagcgaaaag
    38041 ctacagaaag tgctggcgcg tgccggccac ggttctcgcc gtgaaatcga atctattatt
    38101 gaagccggtc gtgtgagtgt tgatggcaaa attgctaaac tcggcgatcg tgttgaagtt
    38161 acccctggat tgaaaatccg tatcgatggt cacctgattt cggtacgtga gtccgctgaa
    38221 caaatttgtc gcgttctggc ctattacaaa ccggaaggtg agttgtgtac ccgtaacgat
    38281 ccggaaggac gtccaacggt gtttgaccgt ctgccaaaac tgcgtggcgc acgctggatt
    38341 gccgtgggtc gcttggacgt taatacctgt ggtctgctgc tgttcaccac cgatggtgaa
    38401 ctggcaaacc gtttaatgca cccaagccgt gaagttgaac gtgaatatgc cgtgcgtgta
    38461 tttggtcagg ttgacgacgc gaaactgcgt gatttgagtc gtggcgtgca gttggaagat
    38521 ggtccggcag cttttaaaac catcaagttc agcggcggcg aagggatcaa ccagtggtac
    38581 aacgtgactc tgaccgaagg ccgtaaccgt gaagttcgtc gtctgtggga agcggttggt
    38641 gtgcaggtga gccgcctgat ccgtgttcgt tacggtgata tcccactgcc aaaaggtctg
    38701 ccacgcggtg gctggacgga gctggacctc gcccagacta actatctgcg cgaactggtg
    38761 gagctaccgc cagaaaccag ctctaaagtc gctgtagaaa aagaccgtcg tcgcatgaag
    38821 gcgaatcaga ttcgtcgtgc ggtgaaacgt cacagtcagg tgagcggcgg tcgtcgttct
    38881 ggcggacgta ataataacgg ttaatcaaag tatgccggac gtcatatccg gcatttttac
    38941 agattaataa tcgatcccta tctgcgcttt tacaccggca tcaaacgcat gtttgacggg
    39001 gcgtaattca cttaccgtat ctgccagttc aagaatatcc cgatgacaac cacgacccgt
    39061 gataatcacc gtctgttgat gtggacgttc atttaacgcc tgcaccactt cttccagtgg
    39121 caaatagtca tacgccacca tatacgtcag ttcatcaagc aaaaccatat ccagtgagga
    39181 atcagcaagc atccgctttg catgttgcca gacttcgcgg caggcggcgg tatcagactc
    39241 gcggttttgt gtatcccagg taaagcccgt tgccatcacc tgaaactcaa cgccatgtgg
    39301 ctccagcaga ttgcgttcgc cattaggcca ggtgccttta ataaactgca cgacgcctac
    39361 tttttttccg tgaccaactg cgcgtgttgc cgtaccaaat gccgcggtgg ttttgccttt
    39421 tccattgccg gtaaagacga tgataatacc gcgttcatcc tgggcctggg ccacacgagc
    39481 atctactttt tctttcactc gctgctgacg ctgttggtag cgttcatcac tcattgggaa
    39541 attcctggtt tacggcccgg ttgggcgtca aaggtcatgc cggttttacg gcggctgtca
    39601 tcgcccatca gccagaggta gagcggcatg atatcagcgg gtgttttaag tttctgtgga
    39661 tcttcggtcg ggaaggcgct ggcacgcatt gcggtgcgcg taccgcctgg gttaatgcag
    39721 ttgacacgca ggcgctgctg atattcatcg gccagtacct gcatcatccc ttcggtggca
    39781 aatttcgacg ctgcatatgc accccagttg gctcgtccct gacgtccaac gcttgatgaa
    39841 gtaaagacca gtgaaccggc gtccgatttg agtaataaag gaagcagtgc ctgggtgagc
    39901 ataaaggtgg cattaacgtt gacctgcatg acgtcctgcc agacctgcgg attttgttcg
    39961 ctcattgggc aaacatcgcc gagcaatccg gcattatgca aaacaccatc cagacgcgga
    40021 taattaacgg caatgcgctg tgccagttgt tggcaatttt cggacgtgca ggtcagcaaa
    40081 tcgagaataa accactgtgg ctgacgccca gtttcttcgt ttatgtggct ggctacctga
    40141 cgtaattttt cttcattacg gcccaacaga atcactgtcg caccatagcg tgcatacgtc
    40201 atcgcggctt cacgaccaat accatcgctg gctcccgtca ccaggataat gcgatcattg
    40261 agtaaatctt gttttggctg gtaatgcatg gctactcctc aacgacgttg tctgtcgcgc
    40321 tgccagtgta ctttatgact ttggggcttt atgcctgaaa cagaagggca tttcaatcag
    40381 cctggggcga taacaccgca aaatggatac tttgtcatac tttcgctgca ataacatctc
    40441 tgcgagacgg cttaacatgc ctgttgtaaa ctgtgagcca aagcgttgtt taaccaaggt
    40501 ggggactcgt ggaattgttg tctgaatatg gtttgttttt ggcgaaaatc gttaccgttg
    40561 tgctagcgat tgcggcgatt gccgccatta ttgtcaatgt tgctcaacgt aataaacgcc
    40621 agcgtggcga gttacgggtc aacaatctca gcgaacagta taaggagatg aaagaagaac
    40681 tggccgcggc gctgatggac tcacatcagc aaaaacagtg gcacaaagcg cagaagaaaa
    40741 agcataagca agaagcgaaa gcagcaaaag cgaaagccaa actgggcgag gtggcaactg
    40801 acagtaaacc ccgcgtctgg gtgctggatt ttaaaggcag catggacgcc catgaagtga
    40861 actcgctacg tgaagagata acggctgtac tcgcagcatt caaaccgcag gatcaggttg
    40921 tgctccgtct ggaaagccct ggtggcatgg tgcatggtta cgggctggcg gcttcgcaac
    40981 tgcagcgtct gcgcgataaa aacattcctt taactgttac ggtagacaaa gtcgctgcca
    41041 gcggcggtta catgatggcc tgtgtggcgg acaaaattgt ttccgcaccg tttgctattg
    41101 tgggttccat tggcgtggtg gcgcaaatgc ccaactttaa ccgcttcctg aaaagcaaag
    41161 atattgatat cgaactgcac actgccgggc agtataagcg cacgctgacg ttgctgggtg
    41221 aaaataccga agaagggcgg gagaaattcc gcgaagagtt gaacgaaacg catcagttgt
    41281 ttaaagattt tgtgaagcgt atgcgtcctt ctctggatat tgaacaggtg gcaacgggtg
    41341 aacactggta cggacaacag gcggtagaga aaggcctggt tgatgaaatc aacaccagtg
    41401 atgaagttat tcttagcctg atggaaggcc gtgaagtggt caatgtacgc tatatgcagc
    41461 gtaaacgact cattgaccga ttcaccggca gcgcggcaga gagcgccgat cgattgttgc
    41521 tacgctggtg gcagcggggt caaaagccat tgatgtaaaa gacaaacgcg aggctaagac
    41581 ctcgcgtttt gctttaatca accagatgat atttttctga aagcacatgg gccaggtgtt
    41641 tgaacatatt aaacaccgcg gtgcttttgg ctgttggcaa tccttgttca tctaaaaagt
    41701 agtcgccggt aaataccagc acgccattac gctgcgtgac gccggtggct tcaatccctg
    41761 cgagcgtatc ctcatgctca cgaatgattt tgttggcctc tttcaacagc gtttcgcggt
    41821 cgatgggttg tgtctctttg ttcattattt actccttaaa caaggacatt agtctacgcc
    41881 aggcatggct tgcagacaaa tataccacgc tggtggcaag agcgccttac tggcaacttt
    41941 ggattttgca tgctaataaa gttgcgtatc ggattttatc aggtacagtg tgacgctttc
    42001 gtcaatctgg caatagattt gcttgacatt cgaccaaaat tccgtcgtgc tatagcgcct
    42061 gtaggccaag acctgttaac tcagtcacct gaattttcgt gaacagagtc acgacaaggg
    42121 gttgatatcc gcagagagcg agtccatatc ggtaactcgt tgccagtgga aggtttatca
    42181 acgtgcgacg cattcctgga agaatcaaat taggtaaggt gaatatgggt aaagctcttg
    42241 tcatcgttga gtccccggca aaagccaaaa cgatcaacaa gtatctgggt agtgactacg
    42301 tggtgaaatc cagcgtcggt cacatccgcg atttgccgac cagtggctca gctgccaaaa
    42361 agagtgccga ctctacctcc accaagacgg ctaaaaagcc taaaaaggat gaacgtggcg
    42421 ctctcgtcaa ccgtatgggg gttgacccgt ggcacaattg ggaggcgcac tatgaagtgt
    42481 tgcctggtaa agagaaggtc gtctctgaac tgaaacaact ggctgaaaaa gccgaccaca
    42541 tctatctcgc aaccgacctt gaccgcgaag gggaagccat tgcatggcac ctgcgggaag
    42601 tgattggggg tgatgatgcg cgctatagcc gagtggtgtt taacgaaatt actaaaaacg
    42661 cgatccgcca ggcatttaac aaaccgggtg agctgaatat tgatcgtgtt aatgcccagc
    42721 aggcgcgtcg ctttatggac cgcgtggtgg ggtatatggt ttcgccgctg ctatggaaaa
    42781 agatcgctcg tggtctgtct gccggtcgtg tgcagtcggt ggcggttcgc ctggtggtcg
    42841 agcgtgagcg tgaaattaaa gcgttcgtgc cggaagagtt ctgggaagtc gatgccagca
    42901 cgaccacgcc atctggtgaa gcgttggcgt tacaggtgac tcatcagaac gacaaaccgt
    42961 tccgtccggt caacaaagaa caaactcagg ctgcggtaag tctgctggaa aaagcgcgct
    43021 acagcgtgct ggaacgtgaa gacaaaccga caaccagtaa acctggcgct ccttttatta
    43081 cctctacgct gcaacaagct gccagcaccc gtcttggatt tggcgtgaaa aaaaccatga
    43141 tgatggcgca gcgtttgtat gaagcaggct atatcactta catgcgtacc gactccacta
    43201 acctgagtca ggacgcggta aatatggttc gcggttatat cagcgataat tttggtaaga
    43261 aatatctgcc ggaaagtccg aatcagtacg ccagcaaaga aaactcacag gaagcgcacg
    43321 aagcgattcg tccttctgac gtcaatgtga tggcggaatc gctgaaggat atggaagcag
    43381 atgcgcagaa actgtaccag ttaatctggc gtcagttcgt tgcctgccag atgaccccag
    43441 cgaaatatga ctccacgacg ctgaccgttg gtgcgggcga tttccgcctg aaagcacgcg
    43501 gtcgtatttt gcgttttgat ggctggacaa aagtgatgcc tgcgttgcgt aaaggcgatg
    43561 aagatcgcat cttaccagca gttaataaag gcgatgctct gacgctcgtt gaacttacac
    43621 cagcccagca ctttaccaag ccgccagccc gtttcagtga agcatcgctg gttaaagagc
    43681 tggaaaaacg cggtatcggt cgtccgtcta cctatgcgtc gatcatttcg accattcagg
    43741 atcgtggcta cgtgcgagta gaaaatcgtc gtttctatgc ggaaaaaatg ggcgaaatcg
    43801 tcaccgatcg ccttgaagaa aatttccgcg agttaatgaa ctacgacttt accgcgcaga
    43861 tggaaaacag cctcgaccag gtggcaaatc acgaagcaga gtggaaagct gtactggatc
    43921 acttcttctc ggatttcacc cagcagttag ataaagctga aaaagatccg gaagagggtg
    43981 gtatgcgccc gaaccagatg gttctgacca gcattgactg cccgacttgt ggtcgcaaaa
    44041 tggggattcg cacagcgagc accggggtat tccttggctg ttctggctat gcgctgccgc
    44101 cgaaagagcg ttgcaaaacc accattaacc tggtgccgga aaacgaagtg ctgaacgtgc
    44161 tggaaggcga agatgctgaa accaacgcgc tgcgcgcaaa acgtcgttgc ccgaaatgcg
    44221 gcacggcgat ggacagctat ctcatcgatc cgaaacgtaa gttgcatgtc tgtggtaata
    44281 acccaacctg cgacggttac gagatcgaag agggcgaatt ccgcattaaa ggttatgacg
    44341 gcccgatcgt tgagtgtgaa aaatgtggct ctgaaatgca cctgaaaatg gggcgtttcg
    44401 gtaaatacat ggcctgcacc aacgaagagt gtaaaaacac acgtaagatt ttacgtaacg
    44461 gcgaagtggc accaccgaaa gaagatccgg tgccattacc tgagctgccg tgcgaaaaat
    44521 cagatgctta tttcgtgctg cgtgacggtg ctgccggtgt gttcctggct gccaacactt
    44581 tcccgaaatc gcgtgaaacg cgtgcgccac tggtggaaga gctttatcgc ttccgcgacc
    44641 gtctgccgga aaaactgcgt tatctggccg atgcgccaca gcaggatccg gaaggtaata
    44701 agaccatggt tcgctttagc cgtaaaacca aacagcaata tgtctcttcg gaaaaagacg
    44761 gaaaggcgac tggctggtca gcattttatg ttgatggcaa atgggttgaa ggaaaaaaat
    44821 aacctttaat tctgtcaggt ttttataaac aaagggtcgc gaaagcggcc cttttttatt
    44881 gcatattatt ttttcttcac acctatacac taaggctata aatgatatag tggttatagt
    44941 tagcaccttt tttattatta aatcgtatta gtcacccgcc aggtgtgacg aaaaaacgat
    45001 gttctgatgg cgtctaagtg gatggtttaa catgaaatta caacaacttc gctatattgt
    45061 tgaggtggtc aatcataacc tgaatgtctc atcaacagcg gaaggacttt acacatcaca
    45121 acccgggatc agtaaacaag tcagaatgct ggaagacgag ctaggcattc aaattttttc
    45181 ccgaagcggc aagcacctga cgcaggtaac gccagcaggg caagaaataa ttcgtatcgc
    45241 tcgcgaagtc ctgtcgaaag tcgatgccat aaaatcggtt gccggagagc acacctggcc
    45301 ggataaaggt tcactgtata tcgccaccac gcatacccag gcacgctacg cattaccaaa
    45361 cgtcatcaaa ggctttattg agcgttatcc tcgcgtttct ttgcatatgc accagggctc
    45421 gccgacacaa attgctgatg ccgtctctaa aggcaatgct gatttcgcta tcgccacaga
    45481 agcgctgcat ctgtatgaag atttagtgat gttaccgtgc taccactgga atcgggctat
    45541 tgtagtcact ccggatcacc cgctggcagg caaaaaagcc attaccattg aagaactggc
    45601 gcaatatccg ttggtgacat ataccttcgg ctttaccgga cgttcagaac tggatactgc
    45661 ctttaatcgc gcagggttaa cgccgcgtat cgttttcacg gcaacggatg ctgacgtcat
    45721 taaaacttac gtccggttag ggctgggggt aggggtcatt gccagcatgg cggtggatcc
    45781 ggtcgccgat cccgaccttg tgcgtgttga tgctcacgat atcttcagcc acagtacaac
    45841 caaaattggt tttcgccgta gtactttctt gcgcagttat atgtatgatt tcattcagcg
    45901 ttttgcaccg catttaacgc gtgatgtcgt tgatgcggct gtcgcattgc gctctaatga
    45961 agaaattgag gtcatgttta aagatataaa actgccggaa aaataatttc ttgcgttatt
    46021 ttcggcacct tttatgtagc gaaggtgccg gaatatattc tcttttgtta cttatttcta
    46081 taccgtgcac aatattttta tccctcatat ttatagggta aattacctgt aaagtagtgt
    46141 ctaattaccc gcctcgcaaa ctccagtttt caaatatcta tttcaggtca aaagattgaa
    46201 ttattcactg gagacgattc gtaaattcgc tggattt
//
LOCUS       DACAOP010000027        45269 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.027, whole genome shotgun sequence.
ACCESSION   DACAOP010000027 DACAOP010000000
VERSION     DACAOP010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 45269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45269
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.027"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..1207
                     /locus_tag="IT892_001688"
     CDS             <1..1207
                     /locus_tag="IT892_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134915.1"
                     /translation="DSSWSSIGSISATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAI
                     GGTLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNN
                     GDSNANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGTIRTVGANLSR
                     AISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYVNTNLTANGSVGWQGKNIAA
                     SGRTDGNAGVIFNTGLEDDGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNS
                     LDSYDIVSGRKSRLTLYPGNVAVIEPEVKQMVTVSGRIRAEDGTLLANARINNHIGRT
                     RTDENGEFVMDVDKKYPTIDFRYSGNKTCEVALELNQARGAVWVGDVVCSGLSSWAAV
                     TQTGEENES"
     gene            1197..2840
                     /gene="ecpD"
                     /locus_tag="IT892_001689"
     CDS             1197..2840
                     /gene="ecpD"
                     /locus_tag="IT892_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial adhesin EcpD"
                     /protein_id="HAP3134916.1"
                     /translation="MRVNLLITMIIFALIWPVTALRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYTGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
                     DAFYQYMQQMPVGSSFTMTINACQTSVNYDASSGARCKDQASGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNLGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            2809..3519
                     /locus_tag="IT892_001690"
     CDS             2809..3519
                     /locus_tag="IT892_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414823.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpE"
                     /protein_id="HAP3134917.1"
                     /translation="MFRRRGVTLTKALLTAVCMLAAPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPRDNRERYYRVSFREVPTRNHTRRSPTGGVVSTEPVVVMDTILVVRPRQVQFKWS
                     FDKVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            3832..4161
                     /locus_tag="IT892_001691"
     CDS             3832..4161
                     /locus_tag="IT892_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HAP3134918.1"
                     /translation="MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLIEQISPF
                     HRCMSGTNQKNPRCIALAGTPGKNACCTIYKNRSSTCREFAMSGENGVVNEACNRARA
                     KYGLTPL"
     gene            complement(4409..5023)
                     /locus_tag="IT892_001692"
     CDS             complement(4409..5023)
                     /locus_tag="IT892_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YagU family protein"
                     /protein_id="HAP3134919.1"
                     /translation="MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
                     VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNAAVYTFAGHVFNWV
                     GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
                     PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
     gene            5441..6130
                     /gene="paoA"
                     /locus_tag="IT892_001693"
     CDS             5441..6130
                     /gene="paoA"
                     /locus_tag="IT892_001693"
                     /EC_number="1.2.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase iron-sulfur subunit"
                     /protein_id="HAP3134920.1"
                     /translation="MSNQGEYPEDNRVGKHEPHDLSLTRRDLIKVSAATAATAVVYPH
                     STLAASVPAATPAPEIMPLTLKVNGKTEQLEVDTRTTLLDTLRENLHLIGTKKGCDHG
                     QCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFIKHDGFQCGY
                     CTSGQICSSVAVLKEIQDGIPSHVTVDLVSAPETTADEIRERMSGNICRCGAYANILA
                     AIEDAAGEIKS"
     gene            6127..7083
                     /locus_tag="IT892_001694"
     CDS             6127..7083
                     /locus_tag="IT892_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase family protein subunit M"
                     /protein_id="HAP3134921.1"
                     /translation="MKAFTYERVNTPAEAALSAQRVPGAKFIAGGTNLLDLMKLEIET
                     PTHLIDVNGLGLDKIEVTDAGGLRIGALVRNTDLAAHERVRRDYAVLSRALLAGASGQ
                     LRNQATTAGNLLQRTRCPYFYDTNQPCNKRLPGSGCAALEGFSRQHAVVGVSEACIAT
                     HPSDMAVAMRLLDAVVETITPEGKTRSITLADFYHPPGKTPHIETALLPGELIVAVTL
                     PPPLGGKHIYRKVRDRASYAFALVSVAAIIQPDGSGRVALGGVAHKPWRIEAADAQLS
                     QGAQAVYDTLFASAHPTAENTFKLLLAKRTLASVLAEARAQA"
     gene            7080..9278
                     /locus_tag="IT892_001695"
     CDS             7080..9278
                     /locus_tag="IT892_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="HAP3134922.1"
                     /translation="MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEE
                     APNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLAVITASNAGALGKGDKNTARLLGG
                     PTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDK
                     NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRT
                     DLAKTLKVPVENVRIISPYIGGGFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIP
                     NNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAVQQSELLYAGANRHT
                     GLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADP
                     TRCFSRRQLIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGAR
                     VHLEQNGTVTVETDMTDIGTGSYTILAQTAAEMLGVPLEQVAVHLGDSSFPVSAGSGG
                     QWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITNGTRSATLHEATAGGRL
                     TAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARS
                     QVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPIS
                     SPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPITLDKLLDKLPDVV"
     gene            9288..10244
                     /gene="paoD"
                     /locus_tag="IT892_001696"
     CDS             9288..10244
                     /gene="paoD"
                     /locus_tag="IT892_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor insertion chaperone PaoD"
                     /protein_id="HAP3134923.1"
                     /translation="MSYPLFDKDEHWHKPEQAFLTDDHRTILRFAVEALMSGKGAVLV
                     TLVEIRGGAARPLGAQMVVREDGRYCGFVSGGCVEAAAAFEALEMMGSGRDREIRYGE
                     GSPWFDIVLPCGGGITLTLHKLRSAQPLLAVLNRLEQRKPVGLRYDPQAQSLVCLPTQ
                     TRTGWNLNGFEVGFRPCVRLMIYGRSLEAQATASLAAATGYDSHIFDLFPASASAQID
                     TDTAVILLCHDLNRELPVLQAAREAKPFYLGALGSYRTHTLRLQKLHELGWSREETTQ
                     IRAPVGIFPKARDAHTLALSVLAEVASVRLHQEEDSCLPPSS"
     gene            10223..10633
                     /locus_tag="IT892_001697"
     CDS             10223..10633
                     /locus_tag="IT892_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134924.1"
                     /translation="MPAPVVLILAAGRGERFLASGGNTHKCIGWRQSPEVAPYRWPFE
                     ENGRTFDLAIEPQITTNDLRLMLRLALAGGGITIATQETFRPYIESGKLVSLLDDFLP
                     QFPGFYLYFPQRRNIAPKLRALIDYVKEWRQQLA"
     gene            10977..11336
                     /locus_tag="IT892_001698"
     CDS             10977..11336
                     /locus_tag="IT892_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004202368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134925.1"
                     /translation="MRMTSRKKEILSYFEPDNLEWVTGEIGAPPFDVSGVAYLLHGMV
                     SFDKRHQLESTRRTLESMVAGGLLERVTVYESRQIRRGGDTNATVVRYGLPGQCAVMR
                     DTGGADNAISGEYMRVS"
     gene            complement(11329..11871)
                     /locus_tag="IT892_001699"
     CDS             complement(11329..11871)
                     /locus_tag="IT892_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid pRiA4b ORF-3 family protein"
                     /protein_id="HAP3134926.1"
                     /translation="MYQLKITIRDSKPPVWRRVLVPEQIPFSKLHAVIQLAFGWNDEH
                     LYMFEKGRKGDPGSEYRVWGEDESMGNAAITPLWAALQNEGDKLVYTYDFGDWWDCVI
                     VLEKQTHDTSNQPISCLRGKGTTPAENSGGLHGYNELLLQARESDNPEQAEIHNFLML
                     DIERRVYDLSRINDRLQAIN"
     gene            complement(11992..12177)
                     /locus_tag="IT892_001700"
     CDS             complement(11992..12177)
                     /locus_tag="IT892_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134927.1"
                     /translation="MTPREIALLTIAKLEHGGHQLTQADQREIERSVNADIARRDRFR
                     EMMRAPAYQWKKPAPRR"
     gene            complement(12475..12756)
                     /locus_tag="IT892_001701"
     CDS             complement(12475..12756)
                     /locus_tag="IT892_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HAP3134928.1"
                     /translation="MIRDRKAEELESKGLYRRAAARWMEVMLLCTEDDDREWIKRRRE
                     TCLENVKRPPVKVEEFGDLHKAVTETQHRMGIAQPNGNAFRLNGGKRQR"
     gene            13178..13504
                     /locus_tag="IT892_001702"
     CDS             13178..13504
                     /locus_tag="IT892_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134929.1"
                     /translation="MDSPLMVIGIILLARVILHWPEPLCVKSMRELHMLCVKLQLKMS
                     CSGGNFLVNSVLVDTNMDTSLLDTTQSQIVTMLNLKQRSLYAPYQIKRSHAQNGLQEN
                     GNLLMG"
     gene            13431..13616
                     /locus_tag="IT892_001703"
     CDS             13431..13616
                     /locus_tag="IT892_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HAP3134930.1"
                     /translation="MRLIKLSEVMLRTGFKKTAIYSWVKTGTFPQPVKIGRSARWSLE
                     EVEAWIQNKLDSRAGNQ"
     gene            complement(14250..14621)
                     /locus_tag="IT892_001704"
     CDS             complement(14250..14621)
                     /locus_tag="IT892_001704"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134931.1"
                     /translation="MAIIIYPRHGIWYIAWVGISNPIPVDGAVTVRAYPLYVKQEDFS
                     DITATAKHQFRDKYAREGYQLQKILQLRPTSMHTMAGGYHKTVLYMRQSGGDVLIIGV
                     YAHRTRYDDVLCGYTNHMYLV"
     gene            14611..15048
                     /locus_tag="IT892_001705"
     CDS             14611..15048
                     /locus_tag="IT892_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134932.1"
                     /translation="MIAILNNAKGRVGVNQLKRLVVSGLLFASFGANAECWIIGDLKG
                     QEASSSDGYNYKLSSIPDTFHLVISKEKADLILAKDGIGGGIDYYPLSPNAMMGRSYR
                     DGQLTLVTWAISNDGKVIHTRTISRSDIGSFTGSFVGNVKGKC"
     gene            complement(15110..17215)
                     /locus_tag="IT892_001706"
     CDS             complement(15110..17215)
                     /locus_tag="IT892_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001570980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="injection protein"
                     /protein_id="HAP3134933.1"
                     /translation="MAKAWKDVIASPQYQALAPEQKAQAQEQYFNEVVAPQAGESVEQ
                     AKQAFYAAYPLPSTNEIDRSQSATQNIQHTSSDNSLASGYAKLATQQREGLERSAEQG
                     ASLGAAMRDAITGESRMTPEMERLQNVDLAPELTSLSMDALKARWSQLFGSDASQEKI
                     LQSMGAKLRQDEKGNTIVSLPSGDYALNKPGLSPQDVASFLANALAFTPAGRAGTVLG
                     AIGKSAATDLALQGATSLAGGEDIDPLQTVISAGIGGIGKGLENTASAVSRAVRGDMS
                     PEAKAAVNFASERNLPLMTSDMLKDKTFMQSQAQTLGERVPFFGTGKNRLNQQQAREN
                     LVRTFSDGLGGISDKQLYESATKGQQKFIEAAGKRYNRIIDAMGDTPVDLSNTVKAID
                     NQIAVLSRPGKSQDRAAVKVLQQFKDDITSGPNDLRLARENRTDLRKRFMASSDTVDK
                     DTLQKASDIIYKAYTADMKKAVAKNLGADEAINMARVDRSWSKFNDMMGRTRVQKAIA
                     SGKATPEDVTKLVFSQSPSERSQLYRLLDDNGRQNARAAIVQNAVDKATDPSGNISVE
                     KFINALHRNRKQSATFFKGVHGKELDGVIKYLNDTRHAAKANVQNLNGQQLYGLLVGG
                     GIINAAVLAGMLKTAAFVVPAAGAVGGAAKAYESPVIRNALLRLANTPKGSTAYDRAI
                     STVTQSLTTAAQASQKEAQ"
     gene            complement(17215..18636)
                     /locus_tag="IT892_001707"
     CDS             complement(17215..18636)
                     /locus_tag="IT892_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001590890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAP3134934.1"
                     /translation="MATWQLGGLPSMAPQNDNAPRSSVPQPVQYQQHPNVGLMALQGL
                     RGVAEINQQARQQQRKAEFQKAYAGAFESGDRNKMRSLISEYPEEFESVQKGMGFIDD
                     DQRNSIGHLATSAQIASSLGTGAFGKFIADNEDEMRRLGISPESVAEMHVNDPQGFQR
                     LAGSMALFSLGHEKYFDIKDQMEGRDIERGKLAETIRSNQAGEALQARGQDISRANAL
                     TSAYAPTAAMQNYNQYAQMLKADLEGAAAFAAAAGINTNAKKLMSVRENDDGTVTKYY
                     TDGSEEQGKLNQPISGDGFRPIALPTAQKIMEKSPEGAKKAAGFAYRVRDALDSIDTL
                     KDQLSPQRVAIINNALGNGTLANLTLSPTEQQYVVNANDAIMAILRQETGAAIAPAEM
                     SKYYQMYFPQPGDSTKTIDTKRRKMENQFNSLKAASGRAYDALRVISAVDRGTSSSSQ
                     TLPQSEQVSQPAASSNFSSLWGD"
     gene            complement(18636..19313)
                     /locus_tag="IT892_001708"
     CDS             complement(18636..19313)
                     /locus_tag="IT892_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001590889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA transfer protein"
                     /protein_id="HAP3134935.1"
                     /translation="MLITHIAHKHLNRAVYEKGGDGGASKAQAKAQQQAIDLQREQWN
                     TVMNNLKPYAEVGLPALQQLQGLMTLEGQNKAANDFFGSGLYKTQADQARYQNLVSAE
                     ATGGLGSTATSNQLSSIAPMLYNNWLSGQMQNYGNLLNVGMNAASGQATAGQNYANNT
                     GQLLQGLGAIRAGQAQQPSSLARGIGGAASGALAGAQLGSVVPGIGNVAGAIGGGLIG
                     LVGGLGF"
     gene            complement(19307..19768)
                     /locus_tag="IT892_001709"
     CDS             complement(19307..19768)
                     /locus_tag="IT892_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013813161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2824 family protein"
                     /protein_id="HAP3134936.1"
                     /translation="MELKFIDNPVRLQAFLNEPGNTENIVEPGHTYYIKPDAVYLGIY
                     EGLVLAGVHEVRNFWHSVVECHAVYDPGFRGEYALQGHRLFCKWLLENSPFLNSITMV
                     PDTTKYGRAIIRLLGATRVGHLDDAYIRCGKPVGVTLYQLTRQQYKEFSEC"
     gene            complement(20531..23287)
                     /locus_tag="IT892_001710"
     CDS             complement(20531..23287)
                     /locus_tag="IT892_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004866290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HAP3134937.1"
                     /translation="MRNIDLIRQVISASENNWPHVLGCLNINVPDSPRRHAPCPACGG
                     KDRFRFDDNGRGSFICNQCGAGDGLDLIKRVNNCDTTEAALLAADVLGIDYRTTETPE
                     ATSQKREQLETERQRREQERLKRAEKDEQQRRDTFSRQFDDMRRKAVNGKSDYLVAKG
                     VGDFTFPVLPDGSLLLALVDKSGAVTAAQTITSHGEKRLLTGSAKRGAYHAINAPETT
                     QSILIAEGLATALSAHLIRPEALTVAAIDAGNLLYVAQVLRDKFPSAQIIIAADNDHS
                     EGRQNTGRIAAEKAALSVSGWVALPPTDHKADWNDYHQKHGIKCATEAFNKSMYQPQG
                     NGVKQEPQTIEGSDFKVMDTDPLKPRIESREDGIYWVSPRADSQSGEIINNESWLCSP
                     LSVIGTGRDDKDQYLILRWLSFGSETPTTAAIPLADIGEREGWRTLKAGGVNVTTKSS
                     LRAILADWLQRSGSRELWRVAHATGWQCGAYIMPDGEIIGTPENPVLFSGRSSAAAGY
                     TVSGSAKSWRDNVARLAFGNYSMMTGIGAALAAPLIGLVGADGFGIHFYEQSSAGKTT
                     TANVASSLYGNPDLLRLTWYGTALGLANEAAAHNDGLMPLDEVGQGADPVSVSQSAYA
                     LFNGVGKLQGAKDGGNRDLKRWRTVAISTGEMDLETFIATSGRKTKAGQLVRLLNIPL
                     SKAVRFHDYQNGKQHADALKDAYQHHHGAAGREWIKWLADHQQQAIKTVRDCESRWRN
                     LIPSDYGEQVHRVAARFAILEAALLLGEVVTGWDAQTCRDAIQHSYNAWLREFGTGNK
                     EHQQIIEQTEAFLNAYGLSRFAPFPYSPADLPIKDLAGYRQRGEHDESPMIFYTFPAT
                     FEKEIACGFNAKQFAEVLKKAGMLTPPNSGRGYQRKSPRIQGRQINVYVLNYQPGDYN
                     SSEE"
     gene            complement(23274..23645)
                     /locus_tag="IT892_001711"
     CDS             complement(23274..23645)
                     /locus_tag="IT892_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001580247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134938.1"
                     /translation="MRENAEMALSSAIGEQVAKIAGAVWIHNLHSTGEEKMAIQTPEG
                     RTITTSLKPSDVCDLICAFMYPAMRTVHGDKWKLATTAEFDMWLNNDGMLTDYGITKW
                     QMLVSHIANAIDHVGYGDAKH"
     gene            complement(23638..23979)
                     /locus_tag="IT892_001712"
     CDS             complement(23638..23979)
                     /locus_tag="IT892_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134939.1"
                     /translation="MITKNFRLNALANKYASALYNHITSTSGGDYFMVDADGEAVRVE
                     IVNGVKGVRSLIDSYTLAAMKVFYPQWETVGIELLERCVTKDGLTDVGREIWQSMVND
                     MGATVAGGSHA"
     gene            complement(23990..24592)
                     /locus_tag="IT892_001713"
     CDS             complement(23990..24592)
                     /locus_tag="IT892_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134940.1"
                     /translation="MNNFLTFHTEATPDGVNIMYRSNDGMTERVEAVSYIDAVNRLDA
                     GDYDDKPDEGMSIHLAIADGGNQGYFDYTSQHNVIMWRWLIATVFMLEMREENGTVSI
                     IDDTGNPSEVAVYSNGIVAMPLYPVAERLAMANNIEGAMIERFGIESGTERAIIFYRA
                     MMDVEQGALTPFGRETLAELHNSFIAELNENGMPAEPVTH"
     gene            complement(24585..24806)
                     /locus_tag="IT892_001714"
     CDS             complement(24585..24806)
                     /locus_tag="IT892_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134941.1"
                     /translation="MTNIQLIEAQCRIEQVQTVLGFWLEGASPSNRDKLMIGAVMSLL
                     NGVPEAIQEADELLGKYELQNHSGEAKHE"
     gene            complement(24803..25066)
                     /locus_tag="IT892_001715"
     CDS             complement(24803..25066)
                     /locus_tag="IT892_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001468267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinic acetylcholine receptor subunit beta"
                     /protein_id="HAP3134942.1"
                     /translation="MNINLIYRHPCELEIESLLGREEPYPDTFTPADCATERLTRART
                     GLVHVMNEIVPSVGGEQATVINSWLQKVTSLIDIGLIDVESAK"
     gene            complement(25063..25257)
                     /locus_tag="IT892_001716"
     CDS             complement(25063..25257)
                     /locus_tag="IT892_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134943.1"
                     /translation="MNNSINTPRLTSALQLIEQAAAVLVAVSLSAEEMDAADVVDAIK
                     ACSSLVNDARAELVILGGEK"
     gene            complement(25250..26317)
                     /locus_tag="IT892_001717"
     CDS             complement(25250..26317)
                     /locus_tag="IT892_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HAP3134944.1"
                     /translation="MLTAQKKIFSLAGMSPKSSNMTAKSDINTADTSKVYHLLVVGAD
                     ALTMSEITVDGVSVEKVSGYAREFLVVDGFLCSCNDSTKTFVHARDVNEMSAMYCASG
                     SSNSEFSESIKKSLPLCGNTVYGYKAPHKTGAGIGVLKILKATYDAPSVFFYVVGLTH
                     PFFGRWCIIQRLCQSMVAQAGASSEAPVSFRAGYANPVWATTSEIGVSGGSVTCYLKE
                     AATCWLLPLPKKRNLSGLSPQFAAIARQLPPKFIILLPSLNAMLAVLWCAITSAFLLV
                     VSAWRWHMIKTYDVHMDPLERTSQIITLTEVINDILVSNSPSRDEKLKALLAILDLAV
                     RDVHFLLEGGQMPCKTGATNE"
     gene            complement(26311..26493)
                     /locus_tag="IT892_001718"
     CDS             complement(26311..26493)
                     /locus_tag="IT892_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HAP3134945.1"
                     /translation="MFKPTGTPQPQKRYKDAHGALVTVESVSHNRVTFYRDGYQSPCV
                     QPLARFMKEFAEVNKC"
     gene            complement(26486..27319)
                     /locus_tag="IT892_001719"
     CDS             complement(26486..27319)
                     /locus_tag="IT892_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001019359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HAP3134946.1"
                     /translation="MNIEKSRLISEAAPHLNASLGTINGNEFAAIVPVIPGHIGGRET
                     NIVSAKALHKALGVGKDFSTWITDRISEYDFTIGHDYSVHKTISPNLGKSPNGAAYSK
                     IKQSGRPGKDYLLSVGMAKELAMIERNDQGRAIRRYFIQCEEELQRSVPEIAARYRRQ
                     LKARISAANNFKPMCDALNMARAEMGKTTQQHHYTNESNMISRIVLGGLTAKQWARIN
                     GYSGEPRDHMNAEQLEHLSYLESTNITLIDMGMEYEQRKGELTRLSQRWLAKRLEAVH
                     V"
     gene            complement(27332..27763)
                     /locus_tag="IT892_001720"
     CDS             complement(27332..27763)
                     /locus_tag="IT892_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134947.1"
                     /translation="MEKKNRPLQAANSDIRVSDITPLTKSLQAPKRTPKKHRARVYML
                     RTGIEGWTENDILRYCRLSSGRNYATELERQLGITLERIDEKNPDGIGTHLRYRFSCR
                     GDVLKVITHINHLANINDHNGLSQQEIADILKLYPDAFNAA"
     gene            complement(27763..27966)
                     /locus_tag="IT892_001721"
     CDS             complement(27763..27966)
                     /locus_tag="IT892_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000035054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HAP3134948.1"
                     /translation="MANYNSLIRLSEVQRRTGYSKAWIYRLISQGRFPKQVKIGSRAI
                     AFVESEIDEWIEKCILESRDEVA"
     gene            complement(28394..29608)
                     /locus_tag="IT892_001722"
     CDS             complement(28394..29608)
                     /locus_tag="IT892_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP3134949.1"
                     /translation="MKLNARQIDTAKPKEKAYKLADGGGLYLLVKPNGGKYWRLKYRV
                     AGKEKLLALGVYPEVTLADARAKREDAKRGIAGGIDPMEAKREEKIARETQLNNTFKD
                     IALEWHSSKLKKWSAGYASDILEAFNKDVFPYIGKKPIAEIKPLELLNVLRRIEGRGA
                     TEKAKKVRQRCGEVFRYAIVTGRAEYNPAPDLTSAMQGHESNHYPFLTAKELPDFFKA
                     LSSYSGSALVVMAARLLIITGLRTGELRGALWDEIDFNKAIWEIPASRMKMRRPHIVP
                     LSEQALSLIGKIREITGNYPLMFPGRNDPRKTMSEASINQVFKRIGYAGRVTGHGFRH
                     TMSTILHEQGYNTAWIETQLAHVDKNSIRGTYNHAQYLDGRREMLQWYADYMDSLEHG
                     GNVVHMVFEKHA"
     gene            complement(29774..29849)
                     /locus_tag="IT892_001723"
     tRNA            complement(29774..29849)
                     /locus_tag="IT892_001723"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(29814..29816),aa:Thr,seq:cgt)
     gene            complement(29964..31217)
                     /gene="proA"
                     /locus_tag="IT892_001724"
     CDS             complement(29964..31217)
                     /gene="proA"
                     /locus_tag="IT892_001724"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAP3134950.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILN
                     ANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     gene            complement(31229..32332)
                     /gene="proB"
                     /locus_tag="IT892_001725"
     CDS             complement(31229..32332)
                     /gene="proB"
                     /locus_tag="IT892_001725"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAP3134951.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     gene            32620..33675
                     /gene="phoE"
                     /locus_tag="IT892_001726"
     CDS             32620..33675
                     /gene="phoE"
                     /locus_tag="IT892_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HAP3134952.1"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNASKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFSISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
     gene            complement(33714..34115)
                     /locus_tag="IT892_001727"
     CDS             complement(33714..34115)
                     /locus_tag="IT892_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HAP3134953.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLRE
                     FHEKLRELLTTLNLKLEPADDFRDEPVKLTA"
     gene            complement(34173..35417)
                     /gene="frsA"
                     /locus_tag="IT892_001728"
     CDS             complement(34173..35417)
                     /gene="frsA"
                     /locus_tag="IT892_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HAP3134954.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEDDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     gene            complement(35509..35967)
                     /gene="gpt"
                     /locus_tag="IT892_001729"
     CDS             complement(35509..35967)
                     /gene="gpt"
                     /locus_tag="IT892_001729"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAP3134955.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            36228..37685
                     /gene="pepD"
                     /locus_tag="IT892_001730"
     CDS             36228..37685
                     /gene="pepD"
                     /locus_tag="IT892_001730"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008783788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HAP3134956.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQGNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVL
                     KSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            complement(37742..38278)
                     /locus_tag="IT892_001731"
     CDS             complement(37742..38278)
                     /locus_tag="IT892_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001329160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HAP3134957.1"
                     /translation="MVVFTRQDVAVTVLETETGRYSDTLRSALVSLDGDNAWALSESW
                     CGTIQWICPSPYRPHHGRKNWFLGIGRFTADEQEQSDAIRYETLRSSGPGGQHVNKTD
                     SAVRATHLASGISVKVQSERSQHANKRLARLLIAWKLEQQQQENSAALKSQRRMFHHQ
                     IERGNPRRTFTGMAFIEG"
     gene            complement(38211..38477)
                     /locus_tag="IT892_001732"
     CDS             complement(38211..38477)
                     /locus_tag="IT892_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134958.1"
                     /translation="MEWYMGKYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQ
                     RVVGMPDLHPGRGYPIGAAFFSVGRFYPARRRGNGAGNRNGPLL"
     gene            complement(38783..39235)
                     /locus_tag="IT892_001733"
     CDS             complement(38783..39235)
                     /locus_tag="IT892_001733"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP3134959.1"
                     /translation="MNNIQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQISAWAQI
                     DESRWKEKLAKSQVWVAIINAQPVGFISRIEHYIDMLFVDPEYTRRGVASALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQRVECRGAWFTNFYMRYKPQH"
     gene            complement(39245..39643)
                     /gene="yafO"
                     /locus_tag="IT892_001734"
     CDS             complement(39245..39643)
                     /gene="yafO"
                     /locus_tag="IT892_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafO"
                     /protein_id="HAP3134960.1"
                     /translation="MRVFKTKLIRLQLTAEELDALTADFISYKRDGVLPDIFGRDALY
                     DDSFTWPLIKFERVAHIHLANENNPFPPQLRQFSRTNDEAHLVYCQGAFDEQAWLLIA
                     ILKPEPHKLARDNNQMHKIGKMAEAFRMRF"
     gene            complement(39646..39939)
                     /gene="yafN"
                     /locus_tag="IT892_001735"
     CDS             complement(39646..39939)
                     /gene="yafN"
                     /locus_tag="IT892_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system antitoxin YafN"
                     /protein_id="HAP3134961.1"
                     /translation="MHRILAEKSVNITELRKNPAKYFIDQPVAVLSNNRPAGYLLSAS
                     AFEALMDMLAEQEEKKPIKARFRPSAARLEEITRRAEQYLNDMTDDDFNDFKE"
     gene            complement(39991..41046)
                     /gene="dinB"
                     /locus_tag="IT892_001736"
     CDS             complement(39991..41046)
                     /gene="dinB"
                     /locus_tag="IT892_001736"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAP3134962.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     gene            complement(41117..41902)
                     /gene="lafU"
                     /locus_tag="IT892_001737"
     CDS             complement(41117..41902)
                     /gene="lafU"
                     /locus_tag="IT892_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lateral flagellar export/assembly
                     protein LafU"
                     /protein_id="HAP3134963.1"
                     /translation="MTTIKLIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSH
                     PPKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEME
                     IVPQGLRVLIKDDQNRNMFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMA
                     YKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDSKNPQSAGNRRI
                     EIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRTR"
     gene            41847..43586
                     /gene="flhA"
                     /locus_tag="IT892_001738"
     CDS             41847..43586
                     /gene="flhA"
                     /locus_tag="IT892_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhA"
                     /protein_id="HAP3134964.1"
                     /translation="MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAI
                     DADLNAGLINQAQAQTRRKDVASEADFYGAMDGASKFVRGDAIAGMMILAINLIGGVC
                     IGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRN
                     QLLASPSVLYTATGIMFVLAVVPGMPHLPFLLFSALLGFTGWRMSKQPLAAEAEEKSL
                     ETLTRTITETSEQQVSWETIPLIEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVIS
                     DGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMALPSSETYGEIDGVQ
                     GNDPAYGMPVTWIQAAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDITQ
                     LHNRLSSTAPRLAEDLSAALNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSTVTKD
                     HILLAADVRLALRRSITHPFVRKQELTVYTLNNELENLLTNVVNQAQQGGKVMLDSVP
                     VDPNMLNQFQSTMPQVKEQMKAAGKDPVLLVPPQLRPLLARYARLFAPGLHVLSYNEV
                     PDELELKIMGALM"
     gene            complement(43810..44307)
                     /gene="rayT"
                     /locus_tag="IT892_001739"
     CDS             complement(43810..44307)
                     /gene="rayT"
                     /locus_tag="IT892_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="REP-associated tyrosine transposase RayT"
                     /protein_id="HAP3134965.1"
                     /translation="MSEYRRYYIKGGTWFFTVNLRNRRSQLLTTQYQMLRHAIIKVKR
                     DRPFEINAWVVLPEHMHCIWTLPEGDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHA
                     IRNTKDYRHHVDYIYINPVKHGWVKQVSDWPFSTFHRDVARGLYPIDWAGDVTDFSAG
                     ERIIS"
     gene            complement(44483..45232)
                     /locus_tag="IT892_001740"
     CDS             complement(44483..45232)
                     /locus_tag="IT892_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAP3134966.1"
                     /translation="MSLPSIPSFVLSGLLLICLPFSSFASATTSHISFSYAARQRMQN
                     RARLLKQYQTHLKKQASYIVEGNAESKRALRQHNREQIKQHPEWFPAPLKASDRRWQA
                     LAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDKGFDCSGLVFYAYNKILE
                     AKLPRTANEMYHYRRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRT
                     GETIRISRLAEPFWQDHFLGARRILTEETIL"
BASE COUNT        10912 a        11793 c        11094 g        11470 t
ORIGIN      
        1 tgacagctca tggagcagca tcggcagcat cagcgccact ctaccgggag gctttagttc
       61 gctgtgggtt aatcaggaaa aaacccgcat tggcaatcaa ttgcgacgta gcgatgccga
      121 caaccgtgca atcggcggca cactcaacct gaactcactg tggtcgaagc tgggcacatt
      181 cagcatcagc tacaatgatg accgccgtta caacagccat tattacacgg cagattacta
      241 tcaaaatgtc tacagcggta cctttggttc gcttggcctg cgggccggta ttcagcgcta
      301 taacaacggc gacagcaacg ccaatacagg aaaatatatc gctctcgatc tctcgctacc
      361 actgggcaac tggtttagcg cagggatgac tcatcaaaac ggctacacca tggcaaacct
      421 gtcagcacgc aaacagtttg atgaaggaac cattcgcact gttggtgcca atctgtcacg
      481 tgccatctcc ggcgataccg gtgatgacaa aaccctcagc ggcggggcgt atgcacaatt
      541 cgacgctcgt tacgccagcg gaacgctgaa cgtcaatagc gcggcggacg gctacgtcaa
      601 taccaacttg accgccaatg gcagcgtcgg ctggcagggt aaaaacattg ctgccagcgg
      661 gcggactgat ggcaacgctg gggtgatatt caacaccggg ctggaggacg acggtcagat
      721 cagcgccaaa atcaacgggc ggattttccc gcttaacggc aagcgtaact atctcccgct
      781 ctctccctat ggaagatatg aggtggagtt acagaacagc aaaaactcac tcgacagtta
      841 cgatatcgtc agcggccgca aaagtcgtct gactctctat ccaggcaatg tcgctgtcat
      901 tgagccagag gtgaagcaga tggttaccgt ctccggtcgt atccgtgcgg aagacggcac
      961 actgctggct aacgcacgga ttaacaacca tatcggccga acccgaaccg atgaaaacgg
     1021 cgagtttgtc atggacgtgg ataagaaata ccccactatc gattttcgct acagtggcaa
     1081 taaaacctgc gaagtggctc tggaactcaa ccaggcgcgc ggtgccgtct gggtcggtga
     1141 tgtggtctgc agcggcctct catcgtgggc ggcggtgacg cagacaggag aagagaatga
     1201 gagttaacct actaataacg atgataattt tcgcgctaat ctggccagta actgcgctca
     1261 gagcggcagt gagcaaaaca acctgggcgg atgcaccggc acgcgagttt gtgtttgtcg
     1321 aaaacaactc agacgacaac tttttcgtca ctcctggcgg ggcgctggat ccgcgcctga
     1381 ccggtgccaa ccgctggacc ggtttaaaat acactggttc aggaaccatc tatcagcaaa
     1441 gcctcggcta cattgataac ggttacaaca ccggccttta taccaactgg aagtttgata
     1501 tgtggctgga aaattcacca gtttcatctc ctttaactgg cttgcgctgc atcaactggt
     1561 acgctgggtg taatatgacc accagtctta tcctgccgca aaccaccgac gccagtggat
     1621 tttatggcgc gacggtgacc agcggcggcg cgaagtggat gcacggcatg ttgtcagacg
     1681 cgttttacca gtatatgcaa caaatgcccg tcggcagcag ctttacaatg accatcaatg
     1741 cctgccagac ctctgtgaac tatgacgcca gcagcggcgc acgctgtaag gatcaggcct
     1801 ccggcaactg gtatgttcgc aacgtcaccc atacgaaagc agcaaatcta cggttgataa
     1861 atacccactc gctggcggaa gtatttatca acagcgacgg agtaccgact ctgggcgaag
     1921 ggaacgccga ctgccggacg caaaccatcg gcagccgttc aggattaagt tgtaagatgg
     1981 ttaactatac cctgcaaaca aacggactca gcaacacctc aatccatata ttcccggcga
     2041 tcgccaactc gtcgttagcc tcggccgtcg gggcgtacga tatgcagttc agtctgaatg
     2101 gcagttcatg gaaaccggtg agcaataccg cctattacta caccttcaac gagatgaaga
     2161 gcgcagactc gatctatgtt ttcttctcga gcaacttctt taagcagatg gtgaacctcg
     2221 ggatcagcga tatcaacacc aaagatctat tcaactttcg ctttcagaac accacatcac
     2281 cggagtctgg ctggtatgaa ttttctacct ccaacacgct gattatcaaa ccccgtgatt
     2341 tcagcatcag tattatctcc gatgaatata ctcagacacc gtcgcgggag ggatatgttg
     2401 gcagcggcga gtcggcactc gatttcggct atatcgtaac caccagcggt aaaacagctg
     2461 ccgacgaagt gctgatcaag gtgaccggac ccgcgcaggt gattggcggg cgctcctatt
     2521 gtgtcttcag ctccgatgac ggtaaggcga aagtaccgtt cccggcgaca ctttccttta
     2581 ttacccgcaa cggagctaca aaaacctacg atgccgggtg cgatgatagc tggcgggata
     2641 tgaccgatgc gctgtggttg accacaccgt ggactgatat ctctggcgaa gtggggcaga
     2701 tggataagac cacagtcaaa ttttcgattc caatggataa cgccatttcg ctgcgtacgg
     2761 tagatgataa cggctggttt ggcgaagtca gcgcttcagg agagattcat gttcaggcga
     2821 cgtggcgtaa cattaactaa ggccctgctg acagcggtct gtatgctggc ggcacctttg
     2881 acacaggcga tttcggtcgg caatctgaca ttttcgctgc cgtccgagac tgactttgtc
     2941 agcaaacgtg tagtgaataa caacaaaagc gcacggatat accgtattgc catcagtgct
     3001 attgatagcc cgggcagcag tgaattgcgc acccgaccgg tggatggtga actgcttttc
     3061 gccccccgcc agctggcgtt gcaggctggt gagagcgagt attttaaatt ttactatcat
     3121 ggtccacggg ataaccgcga gcgctactac cgggtctcat ttcgcgaggt ccccactcgt
     3181 aaccatacaa gacgcagccc aaccggcggc gtggtcagca cggagccggt ggtggtgatg
     3241 gataccattc tggtagtacg accacgtcag gttcagttta aatggtcctt cgacaaggtg
     3301 acaggaacgg taagtaacac tggcaacaca tggtttaagc tactgattaa gccaggatgt
     3361 gattcgaccg aagaggaagg cgatgcctgg tatctacgtc cgggagacgt ggttcatcag
     3421 cctgagttac gtcagccggg gaatcactat ctggtctata acgacaaatt cattaagatt
     3481 agcgattcct gtccggctaa gcccccttcg gcggactaag acttatccat cggtcgaggg
     3541 aagaattcca cctcagagcc ccaaaaatcg tttaaatgat gtggaagcga tcgtcaatat
     3601 cacctgtaac gatgggcttt ctcatatgca caccatagtg ttcaggagac acggaaaggt
     3661 atcaggcagc ctgctaacga gtggtttaat cacgaattag tacgtaaaat cggtaacggc
     3721 tggaaatcat tcaatactca cactatcgaa agttccccag ccaaccgcgg tacgttctta
     3781 catacgatgt accgctgttc tctttacgat ttttagctgt actggtgaat tatgagcaat
     3841 ctgaatccat gcatgacgtg tggtgcctgt tgtgcatttt tccgcgtctc tttttactgg
     3901 gccgaagccg acgatgctgg cggtactatt cccgccaggc tcattgaaca aatatcccct
     3961 tttcaccgat gcatgagcgg taccaatcag aaaaaccccc gatgtattgc ccttgcagga
     4021 accccgggca aaaatgcctg ctgcacgata tataaaaatc gatcgtccac atgcagagaa
     4081 ttcgccatgt ctggtgagaa cggagtcgtc aatgaggctt gcaatcgtgc aagggctaaa
     4141 tacgggctga caccgttata aacatacaat aattaattgc actgccccgc cagcgataat
     4201 agcggggctt cgtttttcag gggtaacaaa acccgatact tcttctattt gccagcaaca
     4261 atgcctctct tctgtagcgt tcttcggatc tacatcatcc tgaagtagcg cgatatactc
     4321 actgactatc tgcatcagaa tataaaaagc aatgttttta acctataaaa atggcgctgt
     4381 atttgcgcca tttttatcat tcaatgcatt atctgtttga gcctaaaggg atctcagggt
     4441 ctggctcatg agtaattctg tttcgtaaat ctctgcgaat aatttcaata gaccagaacc
     4501 agactaaatg tccaaaaatt tcagaaacat tctcatacca cgggagatca aacagaggtg
     4561 gcgtcagtcc catgagaggg aatgaaatca tatgaacaaa aagttgggct aaagcacctg
     4621 ccagtaagcc ctgccagagt ttaatttttg gaaatacttc agcgaccaca caataaccga
     4681 cagcaaacac tatcgaaaag ataatgtgcg taacaccaac ccagttaaag acatgcccgg
     4741 caaaggtata aacagccgca ttgggatctg tcagccccaa ccagtctcga agaaaaatat
     4801 acggtggatt gagaaaatta cgcgagcaat caatttggcc tgcagccctg attaatgatt
     4861 ccgggccaca cgctgcatta aacatatcca ccgggctacg tggcggcaat ggaacttcag
     4921 ccccccactt cacgaatgcg gaaacaacgc cagcaatcag cccaatgaat gcagcaagac
     4981 cataacgtct gcggttcggt ggagtttgtt caaatatatt catatctacc ctgcttgtac
     5041 cattatgtta tacacctctt caggagtatt cataaaacaa ggcaaatgta aagaactgta
     5101 ttgttttgta taacaagata gtttcctaat cgccaatgaa tataagctcc atcatttctc
     5161 cctattttta tattagaagt gacagagatt tgcagggtga tgtagagctg aaaatcacag
     5221 gtttccttat tggtttttgc atcgtacaac taaagcaata aaccagctcc catcatcatc
     5281 aacatcccgg cgaacatgaa tttattagcc gggctcatag ctgcattcgc gttttaagaa
     5341 taatcctcct gctgtcgccg actatgctta acgtttaaaa aagcatcagc actctcgcaa
     5401 cgcactctta ttttcccctt tagaataccg gaggcctggt atgagcaacc aaggcgaata
     5461 ccccgaagat aatcgggttg ggaagcacga gccgcacgat ttaagtttga cccgtcgcga
     5521 tctgattaaa gtgagcgccg caacagcggc gaccgccgtg gtttatcctc attctacgct
     5581 ggcggcaagc gttccggcag ctacacccgc gccagagata atgcccctga cactgaaggt
     5641 gaacggcaaa accgagcagc ttgaggtgga tacccgaacc acgctactgg acactttgcg
     5701 tgaaaatctg catttgatcg gtaccaagaa aggttgcgat cacggacagt gcggagcctg
     5761 taccgtgctg gtcaatggtc gcaggcttaa tgcctgcctg acgcttgcag tcatgcatca
     5821 gggggccgag atcaccacca ttgaaggcct gggttcgcca gataatcttc accccatgca
     5881 ggcggccttt atcaagcatg atggcttcca gtgcggctac tgcacctccg ggcaaatttg
     5941 ctcatcagta gcggtgctaa aagagattca ggacggcatt cccagtcacg tcacggtcga
     6001 tttggtttcc gctccagaaa caactgccga tgagatccgt gaacgtatga gcggcaacat
     6061 ctgtcgctgt ggtgcatacg ctaacatcct tgccgccatt gaagatgctg cgggggagat
     6121 aaaatcatga aggcgtttac ctatgaacga gtgaataccc cagccgaggc ggcacttagc
     6181 gctcagcgcg tacccggcgc aaaatttatc gcgggcggga ccaatctgct ggacctgatg
     6241 aagctggaaa ttgaaacgcc cacccacctt atcgatgtga acggcctcgg gctcgataag
     6301 attgaagtga ccgacgcggg tgggctgcgc atcggcgcac tggtacggaa caccgacctg
     6361 gcggctcacg agcgcgtgcg tcgtgattac gcggtactct cccgcgccct gctcgctggc
     6421 gcgtctggtc agttacgtaa tcaggcaacc accgcaggta atctgctcca gcgcacgcgc
     6481 tgcccctatt tttacgacac caatcagccc tgcaataagc gcctgcccgg gagcggctgc
     6541 gcggcgcttg aaggctttag ccgtcagcac gcggtggtag gcgtaagcga agcctgcatt
     6601 gccacccatc cgagcgatat ggcggtcgca atgcggttgc tggatgcggt ggtggaaacc
     6661 atcacgccgg agggaaagac tcgcagtatc acactggctg atttttatca ccctccggga
     6721 aaaacgccgc acattgaaac cgccctgctt cccggtgagc ttatcgttgc ggtgacgtta
     6781 cctccaccgc tcggcggaaa acatatctac cgtaaggtgc gcgatcgcgc ctcctacgcc
     6841 tttgccctgg tatcggtcgc ggcgattatt cagcctgacg gcagcgggcg cgtcgcgctg
     6901 ggcggagtag cacataagcc ctggcgcatt gaggctgcgg atgctcagct atcccagggg
     6961 gcgcaggccg tatatgacac gctgttcgcc agcgcccatc ccaccgctga aaacaccttt
     7021 aaactcctgt tggcgaagcg aacgcttgcc tccgtactgg ctgaagcgag ggcacaggca
     7081 tgaaatttga taaacccgca ggggaaaacc cgatcgatca gctgaaggtt gtcggtcgtc
     7141 cccatgaccg catcgacgga ccgctgaaaa ctaccggcac ggcacgctac gcctacgaat
     7201 ggcatgaaga agcccccaac gccgcctatg gctatatcgt cggttccgcc attgccaaag
     7261 gacgcctcac cgcccttgat acggacgccg cgcaaaaagc gccgggcgta ctggctgtca
     7321 ttaccgccag taacgccggg gcactcggca aaggcgacaa aaacaccgcc aggctgttag
     7381 gcggccccac tattgagcac tatcatcagg ccattgcgct ggtagtggcc gagaccttcg
     7441 aacaggcgcg agcggcggcc tcgctggtgc aggcacacta tcgccgtaat aaaggagctt
     7501 actccctggc ggacgaaaaa caggccgtca atcagccgcc ggaagacacg cccgacaaaa
     7561 acgtcggtga ctttgacggg gctttcacct ccgctgcggt gaagattgat gctacctaca
     7621 cgaccccgga ccagagccat atggcgatgg agccgcatgc ctcgatggcc gtctgggatg
     7681 gaaataagct taccctctgg acctcaaatc agatgattga ctggtgccgc accgatctgg
     7741 caaaaacgct gaaagttccc gtggagaatg tgcgtattat ctccccgtat atcggcggag
     7801 ggtttggcgg caagctgttc ctgagaagcg atgcgctgct ggcggccctc gccgcccgag
     7861 cggtgaaacg tccggttaaa gtgatgctcc cccgcccctc tattcccaat aacaccacgc
     7921 accgccccgc cacccttcag cacttgcgta tcggtgccga ccagagcggg aaaatcaccg
     7981 ctatctcaca tgaaagctgg tctggaaacc tgcccggcgg cacgccggaa acggcggtac
     8041 agcaaagcga attactctac gccggggcga atcgtcatac cggcctgcgg ctcgccacgc
     8101 ttgatttgcc ggaagggaac gccatgcgtg cgcccggcga agcccccggt ctgatggcgc
     8161 tcgaaatcgc gatcgacgaa ctggcggaaa aagcgggcat cgatcccgtc gagtttcgca
     8221 tcctgaatga cactcaggtt gaccccgccg acccgacgcg ctgcttctct cgccgtcagc
     8281 ttatcgagtg cttgcgcacc ggagcggata aatttggctg gaagcagcgc aacgccacac
     8341 ccggacaggt gcgcgacggg gagtggctag tcggccacgg tgttgcggcg ggctttcgca
     8401 ataatctgct ggaaaaatcg ggtgctcggg ttcacctcga acaaaacggc accgttaccg
     8461 tagaaacgga catgaccgac attggcaccg gcagctacac cattctggcc cagacggcag
     8521 cggaaatgct tggcgtaccg ctggagcagg ttgcggttca cctcggcgat tccagtttcc
     8581 cggtttctgc gggttctggt ggacaatggg gcgcgaatac ctccacctcc ggcgtttacg
     8641 ccgcctgtat gaagcttcgc gaaatgattg cctcggcagt cgggtttgat cctgagcagt
     8701 cgcagtttgc cgacggcaag attaccaacg gtacccgaag cgccacgcta catgaagcca
     8761 ccgcaggcgg cagactgaca gcggaagaga gcattgaatt cggaacactg agcaaagagt
     8821 accagcagtc gacctttgcc gggcattttg tggaggtcgg cgtgcatagc gcgacgggag
     8881 aagttcgggt ccggcgtatg ctcgctgtgt gtgctgcagg acgcatcctg aatccgaaaa
     8941 ctgcgcgcag ccaggtcatt ggcgcaatga ctatgggcat gggcgcggca ctgatggagg
     9001 agctggcggt ggatgaccgt ttgggctact tcgttaatca cgatatggcg gggtatgagg
     9061 tgccggttca tgcggatatc ccaaaacagg aggtgatttt cctggatgat accgacccca
     9121 tatcctcccc gatgaaggcc aaaggtgtcg gtgagctggg cctgtgcggc gtgagcgcgg
     9181 ctatcgccaa cgcggtgtat aacgccaccg gtattcgggt acgggattat cccatcactc
     9241 tggataagct gctcgataag ctgccggatg tggtttaagg aggaacaatg tcatacccgc
     9301 tttttgacaa agacgaacac tggcataagc cagagcaggc gtttctcacc gatgaccacc
     9361 ggaccattct gcgcttcgcc gtagaggcgc taatgtccgg taaaggagcg gtgctggtga
     9421 cgctggtgga gatacgcggc ggcgcggcgc gcccgctcgg ggcgcagatg gtggtgcgcg
     9481 aagatggtcg ttactgcggt tttgtctctg gcggctgcgt ggaggccgct gccgcttttg
     9541 aagcgctgga gatgatgggc tcaggccgcg atcgcgaaat tcgctatggc gaaggttcgc
     9601 cgtggtttga catcgttctg ccctgcggcg gtgggatcac gctgacgctc cataaactac
     9661 gctcggcaca gcctctgctc gccgtgctga accgcctgga acagagaaaa ccggtggggc
     9721 tgcgctacga tccgcaagca caatcgctgg tgtgcctgcc cacgcaaacc cggacgggct
     9781 ggaatctcaa tggctttgag gtggggttca ggccatgcgt caggctgatg atttacggac
     9841 gttctcttga ggcgcaggca accgcgagtc ttgcagcagc cacaggctat gacagccata
     9901 tcttcgatct ttttccggcc tcagccagcg ctcagatcga taccgatacg gcggtcattt
     9961 tgctgtgcca tgatctcaac cgggagctgc cagtgttgca ggccgcgcga gaagcaaaac
    10021 ccttttatct cggcgcattg ggcagctatc gaacccacac gttacgtctg caaaagctcc
    10081 acgagctggg atggtccagg gaggaaacaa cgcaaatccg ggcacccgtc gggatattcc
    10141 ccaaagcccg ggatgcgcat actctggcac tctccgtgct ggcagaagtc gcctctgtac
    10201 gtctccatca ggaggaggat tcatgcctgc ccccgtcgtc ctgatccttg cggccgggcg
    10261 tggagagcgc tttctcgcct ccgggggaaa tacccataag tgtatcggct ggcgtcagtc
    10321 cccggaggtt gcgccttatc gctggccatt tgaagaaaac gggagaactt tcgaccttgc
    10381 gattgaaccg cagattacga ctaatgatct gcgtctgatg ttgaggctgg ctcttgccgg
    10441 cggaggaata acaattgcca ctcaggaaac tttcaggcca tatattgaaa gcggtaagct
    10501 tgtatcgctg cttgatgact ttcttccaca atttccgggc ttctatctgt atttcccaca
    10561 gcgtcgcaat attgcaccaa agctccgcgc cctgattgac tacgtcaaag aatggcggca
    10621 gcaattggct taaatgtctg cacctgcact gcctgatgtc agaacagtat tttgatgaat
    10681 tgccaaggtt acaatggcac aaatacggca caggaggaaa cgtggtgtat ttaaatatgg
    10741 ggtaactctt tgattttaat ggtgcgataa taggaacaat acacataggc gataagcttt
    10801 gtttttgttg ccttttttat tgttcatttt ttatagatac ccccaaaagt acccccatat
    10861 ctttttccgc acctgaaatt tggttgttat tcatacagca tatcaggcgg taacgctctc
    10921 cctttaaccc acttattgta tgatagtgct atcccacaat aaggaatcag ccagccatga
    10981 gaatgaccag tcgcaaaaaa gagatactta gctactttga accggataac ctcgaatggg
    11041 tgactggtga gattggtgcg ccgccgttcg atgtgtcggg tgtggcctac ctgcttcatg
    11101 gcatggtgtc gttcgataag cgtcaccagc tcgaatcaac ccggcgcaca ctggaaagca
    11161 tggttgctgg tggactgctt gagcgggtga cagtgtatga atcgcgccag atacggcgcg
    11221 gcggtgatac taacgcaacg gtcgtgcgct acggtttacc cggtcagtgc gctgttatgc
    11281 gcgatactgg cggcgctgac aacgcaatat caggtgaata catgcgggtc agttaatagc
    11341 ctgcaatctg tcgttgatgc ggctcaggtc gtaaacccgg cgttcaatat ccagcatcag
    11401 gaaattgtgg atctcggcct gctcaggatt atcagactct ctggcctgta atagcaattc
    11461 attgtaacca tgcaagccgc ctgagttttc cgccggggtg gtgcctttcc cacgcaggca
    11521 gctaatgggc tgattactcg tatcgtgtgt ttgcttctcc agcacaatga cgcaatccca
    11581 ccagtcgcca aagtcatacg tgtaaaccag cttgtcaccc tcattctgga gcgccgccca
    11641 tagtggcgtg attgccgcgt tacccatgct ttcatcctca ccccatacgc gatactcgct
    11701 acctggatca cctttacgcc ctttctcgaa catatacagg tgttcgtcat tccagccaaa
    11761 agctaactgg atcacggcat gaagtttact aaaggggatt tgctctggaa ccagcacacg
    11821 ccgccataca ggtggtttgc tgtctcggat ggttatcttt agctggtaca tgcaaatcct
    11881 gaataaatgc gaatcggaag gataacgata ctgacgtact cacaattctg taaaggtgaa
    11941 taaaggaaat ttgcttaata cgcataagtt acatgtggaa taatcccata tctacctgcg
    12001 cggcgctggc ttcttccact ggtaggcagg tgctcgcatc atttcgcgga acctgtcgcg
    12061 ccgggctata tcggcattaa ctgatcgttc tatctcccgt tgatctgcct gtgtaagctg
    12121 gtggcctccg tgctcaagtt tggcgatggt caataaggct atttcgcgtg gtgtcatacg
    12181 tcataccctc tggaaggatg aaacacgccc ggattaaatt tcatttttcg cgggtataaa
    12241 aaaacgatgg ggcgggcagt cccggatagt cagggctgta gagatttgac taccccctcc
    12301 ccactggatt caggttactg ctattccgtt aagcgctgct tacggggata gctgcgttgt
    12361 gattttgacc attcaggtcg ccgctatttc ctcaccgatt gggtgctacg cgcgcgcgta
    12421 cttgtcccga aataccagaa accgccagcc agaggatgat ttccctctgg tggtctacct
    12481 ttgcctcttg ccgccattta accggaaggc gttaccgttc ggttgcgcta tccccatgcg
    12541 gtgttgcgtt tcggtaacag ctttatgcag gtcgccaaat tcctcaacct tcacgggcgg
    12601 gcgcttcacg ttctccagac acgtttcacg gcggcgcttt atccattccc gatcatcgtc
    12661 ctcggtgcat aacagcatga cttccatcca tcgtgcggca gctctccggt atagcccttt
    12721 tgactccagc tcttcagctt tcctgtccct tatcatttct gcctctcaga ttatatagat
    12781 aagcaaaaag gtgttggttc agttggttca gttggttcaa tttgtaaaga gtattgtttt
    12841 taaaagaatt attcgcaaaa agtgaaccaa cacaccccat ttttgaacca acaaaaagag
    12901 gccgtgaacc aacacgccgt ttaaaaaccg ctaattatga gggacattca ccagcacagg
    12961 gcttgtctag tgctggttag gtgctgctca ccgcgcacgg agcggcgctg gtttgctcca
    13021 gcgatatgcg gggctggtca tcatttcgcg gtaccgcctg gctattacag ggccctctgc
    13081 cagctggcgc cttaattccc gcagttctgc cgggctgagc tggtggccgc catgctccag
    13141 cttggcaatg gtcagcagct cgatttctcg tggtgtcatg gattcccctc tgatggtgat
    13201 cggcattata ttgctagcca gggtgattct tcactggcca gagccgttgt gcgtgaagtc
    13261 tatgcgtgaa ctccatatgc tatgtgttaa gttacagctc aaaatgtcct gttccggtgg
    13321 taactttttg gtaaacagcg ttttggtgga taccaacatg gatacctcgc ttttggatac
    13381 cacccaaagc cagattgtca ctatgcttaa tctaaagcag aggagcctct atgcgcctta
    13441 tcaaattaag cgaagtcatg ctcagaacgg gcttcaagaa aacggcaatc tactcatggg
    13501 ttaagacggg cacgtttcca cagccagtta aaattggtag atcagctaga tggtcgcttg
    13561 aggaggttga agcttggatc cagaacaaac ttgattcgcg ggctggcaac caatgattag
    13621 ctttaatatc gagtggtgga tagtccatgg acaagctgat gggcgcactc gacgaaaacg
    13681 atgcgccagg cggactgtgt cgctcataaa ccgggagttg gccagaggac ttagttgtcc
    13741 tttgcaattc tgcaggttcg cacgtgaaag tagccaaaac cctgcgaacc tgagtgcaaa
    13801 cctgcaactg cgaaccactg aggtggcctc tcatagctgg tggtcatact ggatattaat
    13861 caggcctgcc acaaccataa caatccataa cagacgcatc gcaccaacaa ttactaatag
    13921 gtccgctcgc aacactaatt ttgactaagc ctgaacgcaa tgctcagaaa gaacgaagaa
    13981 tggaatgaat cgtaccatca tgttgctcca tgatttttac gttcaagaca gttgcttaat
    14041 ctcgcctcgc aattcagccc ccttgccgtt atcgagaagt ctttctcctt acggttaatg
    14101 ctatcggtct tcatattacc agcagcatac gccatccgat tatttcgatg ctacgcgcgc
    14161 gtacttgtcg caaaatacca ggcaaaggcc agattcagaa cgtcgtgata accaccagta
    14221 caacatgaga ggtcatgtaa cgcgatttat cacaccagat acatgtgatt ggtgtacccg
    14281 cataaaacat cgtcatagcg cgtcctgtgc gcatatacgc cgataatcaa cacatcacca
    14341 ccactctgtc tcatgtagag aacagtttta tggtatcccc ccgccatcgt gtgcatactg
    14401 gtcggacgta gttgcaaaat tttttgcaac tgatacccct cgcgcgcgta cttgtctcga
    14461 aattggtgtt ttgctgtggc agtgatatca gaaaaatctt cctgtttcac ataaagcgga
    14521 tatgcgcgta ctgtaacggc cccatcaacg gggatcggat ttgaaatccc gacccaagct
    14581 atgtaccaaa tgccatgtct tggatatatg atgattgcca ttctaaacaa cgctaaaggg
    14641 agggttggtg tgaatcaatt gaagcgattg gttgtctccg gtttattatt tgcttctttt
    14701 ggagcgaacg ctgaatgctg gattattggt gatctgaaag gacaagaagc ctcaagttca
    14761 gatgggtata actataagtt atcatctata ccagatacat ttcatttggt aataagtaaa
    14821 gagaaggcgg atcttatctt ggcaaaagat ggtataggtg gaggtattga ttattacccg
    14881 ctatctccga atgccatgat gggaagaagc tatcgagatg gtcaactgac gcttgtcaca
    14941 tgggcaatct caaatgacgg aaaagtgatc catacacgaa caattagtcg atctgatata
    15001 ggctcattta caggctcatt tgtcggcaat gttaaaggca agtgttaatg ttcataacta
    15061 tttgaaaaaa tactaattac tattataacc aaccatccat ggtcatctgt tattgagctt
    15121 ccttttgcga tgcttgtgct gctgtggtca gtgattgtgt gaccgtactg atcgctctgt
    15181 catatgctgt gctacctttt ggcgtatttg ccagacgtaa caaggcattt cgtataacag
    15241 ggctttcgta tgccttcgct gctccgccta cggcaccagc agcaggaaca acaaacgcag
    15301 ccgtttttag catccccgct aatactgctg cgtttatgat gccaccacca actaacaatc
    15361 cataaagctg ctgaccattt aagttttgaa cgttcgcttt tgccgcgtgt cttgtatcgt
    15421 tgaggtattt aataacgccg tccagttcct ttccatgtac gcctttaaag aaagttgctg
    15481 attgcttcct gttccggtgt aacgcattaa taaacttctc aacactgata tttccagacg
    15541 gatcagtcgc cttatctaca gcattctgaa ctatggctgc tcgtgcgttt tgcctaccat
    15601 tgtcatccag aagcctgtaa agctgagaac gttctgatgg gctttggcta aaaacgagtt
    15661 ttgttacatc ctcaggcgtg gccttgccgc tggctattgc cttttgaacg cgcgttcttc
    15721 ccatcatgtc attgaattta gaccatgagc gatcaaccct tgccatatta atggcttcgt
    15781 ctgctccaag atttttggct acggcttttt tcatatccgc cgtatatgcc ttgtagataa
    15841 tatcgctggc tttctggagc gtatctttat caacagtgtc agatgacgcc ataaatcgct
    15901 ttcgaagatc ggttctgttt tccctcgcca gacgcaggtc atttggtccg ctggtgatat
    15961 cgtctttaaa ttgctgcaag acttttaccg cggctctatc ctgagatttg cccgggcggc
    16021 ttaacacggc aatctgattg tcgatagctt ttaccgtgtt tgagagatcg acaggggtat
    16081 cccccatagc gtcaattatg cggttatatc gctttcccgc tgcctcaatg aatttttgtt
    16141 gccctttagt cgcagattca taaagctgtt tatcagaaat gccacccaga ccatcgctaa
    16201 atgttctgac taaattttct cgtgcttgtt gttgattcag ccgattctta ccggttccaa
    16261 aaaaaggaac tctttcgcct aatgtctgag cctgactctg cataaaggtt ttatctttca
    16321 gcatgtcact ggtcattaac ggcagatttc tttccgatgc aaagttgaca gcagcctttg
    16381 cttcaggcga catatcacca cgaacagccc tcgaaaccgc actcgctgta ttttccagcc
    16441 ccttaccaat accaccaatg ccagcagaaa ttaccgtttg taacggatca atatcttctc
    16501 caccagcaag gctggtggct ccctgtagtg ctaaatctgt agctgctgat tttcctatgg
    16561 caccaagcac cgttccagcc ctgcccgctg gtgtaaacgc cagcgcatta gccagaaacg
    16621 atgccacgtc ttgcggcgat aaacccggct tgttcagagc ataatcaccg gatggcaggg
    16681 aaacgatagt gttacccttc tcatcctgcc ttaatttcgc tcccatgctc tgaagaatct
    16741 tttcctgaga tgcgtcagag ccgaaaagtt gagaccatcg agcttttaga gcatccatgc
    16801 tgagtgaggt taactctggg gcaaggtcga cattttgcag tctctccatc tctggagtca
    16861 ttcggctttc gcctgttata gcatcgcgca tagcagcccc aagactggct ccctgttctg
    16921 ctgaacgctc aagcccctct ctttgctgag tagctaactt tgcataccct gacgcaagag
    16981 aattatcaga tgatgtatgt tgaatatttt gagttgctga ttgggatcgg tctatttcat
    17041 tagttgatgg tagtggatag gcagcataaa aagcctgctt agcctgctct acactttctc
    17101 cggcttgcgg ggcaacgact tcattgaagt attgctcctg agcctgcgct ttttgttctg
    17161 gtgctaacgc ctgatactgt ggagaggcga taacatcttt ccatgcttta gccattaatc
    17221 accccatagt gaagaaaagt tactgctggc tgctggctgt gatacctgct cagattgcgg
    17281 caatgtctgc gacgaagaag aagttcctct gtcaactgct gaaataaccc gcaaagcatc
    17341 ataagctcga ccagaagcag ctttcagcga attgaactgg ttttccatct tccggcgctt
    17401 ggtatcaatg gtttttgtgg agtcgccagg ctgagggaaa tacatttgat aatattttga
    17461 catttcagca ggtgcgatag ctgcccctgt ttcctgacgg agtattgcca ttattgcgtc
    17521 attagcatta acaacgtatt gctgctctgt tgggctgagc gttaagttag ccagcgtccc
    17581 attacccaaa gcattattaa tgatcgccac tcgctgtggg ctaagctggt ctttcagtgt
    17641 atctattgaa tcaagagcat ccctaaccct gtatgcaaat ccagcagctt ttttagcccc
    17701 ttctggcgac ttttccatga tcttttgggc tgttggcaaa gctattggac gaaacccatc
    17761 tccagatatt ggctggttta gttttccctg ctcttcactt ccgtctgtgt agtattttgt
    17821 gacagtgcca tcatcgtttt ctctaacact cattaatttt ttggcgtttg tattaattcc
    17881 agccgctgcc gcaaatgccg ccgccccctc tagatccgcc tttaacattt gagcgtactg
    17941 attgtaattc tgcattgctg ctgttggtgc atatgctgac gttaacgcat ttgctcggct
    18001 aatatcctgc cctctcgcct gaagtgcttc gccagcctga ttgctgcgga ttgtctctgc
    18061 caacttgcca cgctcaatat cccgaccttc catttgatct ttgatatcga aatacttctc
    18121 atgaccgaga gaaaacagtg ccatactacc agcaagccgc tggaatccct gtggatcatt
    18181 aacatgcatt tcggcaacag actcaggaga aattcccaag cgacgcattt catcttcgtt
    18241 atctgctatg aattttccaa atgccccagt tccgagcgaa gatgcgattt gagcactagt
    18301 cgcaagatga ccaatagaat ttctctggtc gtcatcaata aagcccatcc ctttctgaac
    18361 gctttcaaat tcttctggat actcagaaat aagactgcgc attttgtttc tgtctccaga
    18421 ctcaaaagcc ccggcatatg ctttctgaaa ctctgcttta cgctgttgtt gacgtgcctg
    18481 ctgattaatc tcagcaacgc ctcttagccc ctgtagcgcc attaaaccta cgtttgggtg
    18541 ctgctgatac tgcacaggct gaggaacgga agaacgagga gcattatcat tttgcggtgc
    18601 catgctaggc agcccgccaa gttgccatgt cgccattaga atccaagccc cccaacaaga
    18661 ccaataagcc caccaccaat agccccggcg acattaccta tacccggaac aacggaacca
    18721 agttgcgcac ccgctaaagc gcctgatgcc gccccaccaa taccacgcgc aagactggat
    18781 ggctgctgcg cctgacctgc acgaatagcg ccaagcccct gcaagagttg cccggtatta
    18841 ttggcgtagt tttgccctgc tgttgcctgc cctgatgccg cattcatccc gacatttagc
    18901 aggtttccat aattttgcat ttgcccactg agccaattgt tataaagcat gggcgcaatg
    18961 gaagataact ggttactggt agctgttgag ccaagccccc cggtagcttc tgctgagaca
    19021 aggttctgat aacgggcctg atctgcctgt gttttatata aaccagaacc aaagaaatca
    19081 ttcgcggctt tattctgccc ttccagagtc atcagtcctt gcagttgttg taaagcaggc
    19141 aatccgactt ctgcatacgg cttgagatta ttcatcaccg tattccactg ctcgcgctgc
    19201 aaatcaattg cctgctgctg ggccttcgcc tgagctttag aggcaccacc atcaccgcct
    19261 ttttcgtata cggcacgatt gagatgttta tgagctatat gggtaattaa cattcgctga
    19321 attccttata ttgttgccga gttaactgat aaagcgttac gccgacgggt ttaccacatc
    19381 tgatataagc atcatcaagg tgaccaacac gggtagcgcc aagcaaacgg ataattgccc
    19441 gtccatattt cgtggtgtca ggaaccatag tgatgctgtt aaggaatggt gagttttcga
    19501 gaagccattt gcagaataat cgatgccctt gcagtgcata ttcaccacgg aatccggggt
    19561 cgtacaccgc atggcattca acaacgctat gccagaagtt acgcacttca tgaacgccag
    19621 ccagcactaa tccttcgtag atgccgagat ataccgcatc aggcttgatg tagtacgtgt
    19681 gccccggctc aacaatattt tcggtattgc ctggctcgtt aagaaaggcc tgtaatcgca
    19741 cagggttatc aataaatttt agttccatgc gatgccatcc attttcacat acagcctgcc
    19801 agcgccttat ctattaaccc tcgtgcaatt tcatgcagag ttggcgctac tccaattcct
    19861 gattttttac gctgctcttc ctgaattttc tttatcgctt ccatttgctt ctcacttatc
    19921 aataccggct ttactgaaat agccataacg cccccttata actgtataaa acaacagtta
    19981 ttatagtttc acaaatcgca atattcatca tcgtaattgc agaatatgaa acaaatagca
    20041 caaaaaaatg ccaccgctca gtagctggtg gcgtcgttct gtgtgtcagg ttttgacagg
    20101 ttttttatgg actctaaaaa ctatatttat ggtgtcgcat tactcttcac ggcaggcgct
    20161 tttcagttct gcccttgctt ctggctccat tggtaatttg attcgcgatc agctatgcgg
    20221 atggtttgct gaacaggcat aacaacttct tagaggctgt tttttgaact acgaaaattt
    20281 cgtagtgctc actttcaaaa acgtcacgcc cttgtacaca ggattttacg aaagtctcgt
    20341 aaaacactct ctgatgccag ccaggtgttg tgcgcatcaa ttcagtcaca ttgtgttggt
    20401 tcaaaatacc gtgttgttgg ttcagtgttg gttcaataaa aagaataaaa tccttataaa
    20461 acaataccct ttacaaattg aaccaactga accaactgaa ccaacacctt ttctacgcac
    20521 atgaagaagc tcattcttca gatgagttat aatctcctgg ctggtaattg agtacataaa
    20581 cgtttatttg tcgtccctga atacgtggtg attttctttg gtatccacga ccgctgtttg
    20641 gtggggttag catcccggct tttttcaaca cttcagcaaa ctgttttgcg ttgaaaccac
    20701 atgcgatctc cttttcaaat gtggccggga atgtatagaa aatcattggg ctttcgtcat
    20761 gttctccacg ctgacggtat ccggctaaat ctttgatggg caaatctgcc gggctgtatg
    20821 gaaatggtgc aaaacggcta agcccatagg cattaagaaa tgcctccgtt tgttcaataa
    20881 tctgctgatg ttctttgtta cctgtgccga actcgcgcaa ccatgcgtta tagctgtgct
    20941 gtatcgcatc acggcatgtc tgagcatccc agcctgttac aacctcgcct aacagcaatg
    21001 cggcctccag aatggcaaat cgcgcggcta cacggtgaac ctgctcacca taatcggatg
    21061 ggatcaggtt tctccatctg ctttcgcaat cacgaacggt tttaatagcc tgttgctggt
    21121 ggtctgccag ccatttaatc cactcacgcc cggctgcgcc gtggtgatgc tggtaagcgt
    21181 ctttcagtgc gtctgcgtgc tgttttccgt tctggtaatc gtgaaagcgt actgctttac
    21241 tcaacggaat attcagcagt cgcaccagtt gcccggcttt ggtttttcgc ccggaagtag
    21301 cgataaatgt ttctaaatcc atttctccgg tgctgattgc cactgtacgc cagcgtttta
    21361 gatcccggtt tccaccatct ttagcgcctt gcagtttccc tacaccgtta aataacgcat
    21421 aggcagactg tgaaacgctg acaggatcag cgccctgacc aacttcatca agcggcatta
    21481 gtccgtcatt gtgggcggcg gcctcatttg ccagccccag cgcggttccg taccacgtca
    21541 gccgcagtaa atcagggttg ccgtataagc tgctcgccac gtttgccgtg gtggtcttac
    21601 ctgcgctcga ctgctcatag aaatgaatgc cgaacccgtc agcgcccacc agcccaatca
    21661 atggcgctgc cagtgctgcg ccgatcccgg tcatcattga atagttacca aaggccagac
    21721 gcgccacgtt atcacgccag cttttcgcgc tccctgagac ggtatatccg gctgcggctg
    21781 agcttctccc gctgaacagc acaggatttt caggtgttcc gatgatttcc ccatcaggca
    21841 tgatgtacgc tccgcattgc cagccagtgg catgagcaac acgccacaat tcacgagagc
    21901 cactgcgttg tagccagtct gccagtattg ctctgaggct gcttttggtc gtgacattta
    21961 ccccaccagc tttaagtgtg cgccatcctt cacgttcacc aatatcagcc agtggaatgg
    22021 cagcggttgt cggcgtttca gaaccaaacg acagccagcg aagaatgaga tactggtctt
    22081 tatcgtctct gccagtaccg ataacgctta acggagaaca taaccagctt tcgttattga
    22141 tgatttctcc actctggctg tcagctctcg gagataccca ataaatacca tcctcgcggc
    22201 tttctattct tggtttcagt gggtcggtat ccataacctt aaaatcgctt ccctcaatgg
    22261 tctgtggctc ctgtttcacg ccattaccct gtggttggta cattgactta ttgaacgctt
    22321 ctgtggcgca tttaatgccg tgtttttggt ggtaatcatt ccagtctgct ttgtgatctg
    22381 tcgggggtaa tgccacccat ccagaaacag ataaagctgc tttttctgct gctattctcc
    22441 ccgtgttttg tcttccttcg ctgtggtcgt tatccgcagc aatgatgatt tgtgctgaag
    22501 gaaatttatc ccgcagtacc tgggcgacat ataacaggtt cccggcatca atcgccgcca
    22561 ctgtcagcgc ctctggacga attaaatggg cagataatgc cgttgccagc ccttctgcga
    22621 ttaagatgct ctgtgttgtt tctggcgcgt ttatggcgtg atatgccccc cgctttgctg
    22681 aacctgtcag gagtcttttt tcaccatgtg atgtaatagt ctgtgctgct gtgactgcgc
    22741 cggatttatc caccagcgcc agcaacagag atccatcggg caacacgggg aatgtaaaat
    22801 cacctacccc tttcgcaacc agataatcag atttgccgtt tacagccttt ctgcgcatgt
    22861 catcaaactg acgggaaaac gtatcccgtc tttgttgttc gtccttctct gcccttttca
    22921 ggcgctcctg ttcgcgtcgc tggcgctcgg tttccagttg ttcccgtttc tggctggtgg
    22981 cttctggtgt ttccgttgtc cggtaatcaa tacccagaac atcagcggca agaagcgccg
    23041 cctctgttgt gtcgcagtta tttacgcgtt taattaaatc cagcccatca ccagcgccgc
    23101 actgattaca gatgaagcta ccgcgcccgt tgtcatcgaa ccggaatcga tctttgcccc
    23161 cacatgcagg gcagggagca tgacggcgcg gagagtcagg gacatttatg ttcaggcagc
    23221 ccagcacatg aggccagttg ttttcagacg cactgataac ctgacggata agatcaatgt
    23281 ttcgcatcac cgtaccccac gtggtctata gcgtttgcga tatggctaac cagcatctgc
    23341 cacttggtta ttccgtaatc agtcagcatg ccatcattgt ttagccacat atcaaattca
    23401 gcggttgtcg caagtttcca cttatcgccg tggacagtcc tcattgctgg gtacatgaat
    23461 gcgcaaatca gatcacaaac atctgacggc ttcagagatg tagtaatggt gcgtccctct
    23521 ggcgtctgaa ttgccatttt ctcttcacca gtagaatgaa ggttatgaat ccacacagca
    23581 ccagcaatct ttgccacctg ctctccgatt gcggagctaa gcgccatttc tgcattttca
    23641 cgcatgagaa cctcccgcta cagttgcgcc catgtcatta accatgcttt gccatatctc
    23701 acgcccgacg tcagtcaatc cgtccttagt gacgcaacgc tcaagaagct cgatccccac
    23761 ggtttcccac tgcgggtaga acactttcat ggctgccagt gtgtagctat cgatcaggct
    23821 gcgaacgcct tttactccat taacgatttc cacacgtacg gcctcgccgt ccgcatcaac
    23881 catgaaatag tccccgccgc tggtggaggt aatgtggtta tacagtgccg acgcatactt
    23941 atttgccagc gcattcagtc ggaaattttt agtaatcatg gctccatcct cagtgcgtca
    24001 ctggttccgc tggcatgccg ttttcattca gttcagctat aaagctgttg tgaagttcag
    24061 caagcgtttc acgaccaaat ggagtcagtg ctccttgttc cacatccatc atggctctgt
    24121 agaaaatgat ggcgcgttct gtgccagact cgatgccaaa acgttctatc atcgctccct
    24181 caatgttgtt tgccatagcg aggcgctctg ctactggata cagcggcatg gcgacgatgc
    24241 cgttggaata aacagccact tcggaaggat tgccagtatc atcaatgatg ctgacagtgc
    24301 cgttttcctc tctcatttcc agcatgaata ctgttgcgat cagccatctc cacataatga
    24361 cgttatgctg tgatgtgtaa tcgaaatatc cctggttgcc gccatcggca atagcgagat
    24421 gtattgacat accttcatct ggtttatcgt cataatcccc ggcatccaga cgatttacgg
    24481 catcaatata tgagacggcc tcaacgcgtt ctgtcatgcc atcgttgctg cggtacatga
    24541 tgtttacgcc gtcaggcgtt gcttctgtat ggaaagttaa gaaattattc atgtttcgcc
    24601 tcgcctgaat gattctgtaa ctcatatttg cccaacaatt cgtccgcttc ctgaatagct
    24661 tctggtacgc cattgagcag tgacataacc gcgccaatca ttaacttgtc tctgttgctg
    24721 gggctggccc cttcaagcca gaaccctaaa acagtctgaa cctgttcgat gcgacattgc
    24781 gcttcaatga gctggatgtt ggtcatttcg cactctccac atcgattaaa ccgatatcta
    24841 tcagggaggt aactttttgt agccagctat tgattactgt cgcctgttcc ccgcccaccg
    24901 agggaacaat ctcattcatc acatgaacca gacctgtgcg cgctctggta agccgttcag
    24961 tcgcgcaatc tgcgggagtg aatgtgtctg gatatggctc ttcacgcccc agcaatgatt
    25021 caatttccag ctcacacgga tgacgataaa ttaagttgat attcattttt caccaccaag
    25081 aattaccagc tctgcacggg catcgttaac caaagatgag cacgctttaa tcgcatccac
    25141 gacatcagca gcgtccattt cttcagccga aagactgaca gcaaccagga cagccgctgc
    25201 ttgctcgatt aattgaagtg cggacgtaag gcgaggggta ttaattgagt tattcattgg
    25261 ttgcccccgt tttgcatggc atttgtccac cttccagcag gaaatgaacg tcacgaacgg
    25321 cgaggtccaa tatcgcgagt aacgccttca gtttttcgtc tcgtgaggga gagttgctca
    25381 ccagaatgtc attaatcact tctgtcagtg tgatgatctg gcttgtgcgt tcgagggggt
    25441 ccatatgcac atcgtaggtt ttaatcatgt gccacctcca tgcggatacg accagcaaaa
    25501 aagcagatgt gatcgcgcac cagagaacgg cgagcatcgc gttcagactc ggcagcaata
    25561 tgatgaattt tggcggtaat tgtcgggcaa tcgcggcgaa ctgcggcgat aatccagata
    25621 aattgcgttt tttgggtagg ggtagtagcc agcatgtggc agcctccttc agatagcagg
    25681 ttacgctacc accggaaacg ccaatttcgc tggtggtagc ccagacaggg ttggcgtaac
    25741 cggctctgaa ggataccggc gcttccgaag aagcccccgc ctgagccacc attgattgac
    25801 aaaggcgctg gattatacac caacgcccaa aaaatgggtg agtcagacct acgacataaa
    25861 aaaagacgct cggcgcgtca tatgtcgcct tcagaatttt caggacgcca atcccggcac
    25921 ccgttttatg aggtgcctta taaccataaa ccgtgttgcc gcataacggc aagctctttt
    25981 ttatggactc cgaaaactca ctattggaag aaccagaagc acagtacatc gcgctcattt
    26041 cgttaacgtc acgcgcgtgg acgaaggttt ttgtggagtc attacacgag cagagaaagc
    26101 catctacgac cagaaattct ctggcatagc cgctgacctt ctcaacgcta acaccatcga
    26161 ccgtaatttc tgacatagtt aaggcatccg ctcctaccac cagcaaatga taaactttgc
    26221 ttgtatctgc tgtattaatg tctgactttg ctgtcatatt gctggatttt ggcgacatac
    26281 cagccagtga aaatatcttc ttctgggcgg ttagcatttg ttaacctccg cgaactcctt
    26341 catgaaacgt gccagcggtt gtacgcatgg cgattgatac ccgtcgcgat aaaacgtcac
    26401 tcggttgtga gacacgcttt cgacagtaac gagtgctccg tgggcatctt tgtagcgttt
    26461 ttgaggttgt ggtgttcctg tcggcttaaa catggaccgc ctccagacgc ttggcgagcc
    26521 agcgttgcga caggcgggtg agttctcctt tgcgctgctc atattccatg cccatatcaa
    26581 ttaacgtgat attggtgctt tcgagatatg agaggtgctc aagctgttct gcgttcatat
    26641 ggtcgcgagg ttcgccagaa tagccattta tccgcgccca ctgcttagca gttagcccac
    26701 caagaacgat acgagaaatc atattgctct cgtttgtgta gtggtgttgc tgcgtcgttt
    26761 tccccatctc ggcacgggcc atattcagcg catcgcacat tggcttaaag ttgtttgcgg
    26821 cactgatacg ggcttttagc tggcgacgat agcgggcggc gatttcaggc acgctacgct
    26881 gtaattcttc ctcgcactgg atgaaataac gacggatagc gcgaccctga tcattgcgtt
    26941 cgatcattgc cagttctttc gccattccga cacttaacag atagtctttg ccgggtctgc
    27001 cagactgctt aatcttgctg taagccgcgc cattcgggct tttccccaaa tttggggaaa
    27061 ttgttttatg gactgagtaa tcgtgcccaa tggtgaagtc atattcagag atgcgatcag
    27121 tgatccatgt agagaagtct tttcccacgc ccaacgcttt gtgtaacgct tttgcgctaa
    27181 caatattggt ttcacgccca ccgatatgac caggaataac cgggacaatt gcggcaaatt
    27241 cattaccgtt aattgtgccc agagaggcgt tcagatgagg ggcagcctca gaaattaatc
    27301 tgcttttttc gatgttcatt ttcagtctcc gttaggcggc gttaaacgcg tccgggtaga
    27361 gtttcagaat gtcggcaatt tcctgctgag aaagtccgtt gtgatcattt atgttcgcaa
    27421 gatggttaat atgagtgatc actttcagaa catcaccacg gcaggagaaa cggtagcgaa
    27481 ggtgtgttcc gataccatca ggattctttt cgtcgatacg ctccagagtg attccaagct
    27541 ggcgttctaa ctctgttgca tagttacgac cagaagacag acggcagtag cgaagaatgt
    27601 cgttttctgt ccatccctct ataccagttc gcagcatata gactcgggca cgatgctttt
    27661 tcggtgtgcg ctttggtgct tgaagggatt ttgtaagggg cgtaatatca gatacgcgaa
    27721 tatctgaatt agccgcctgt aatgggcggt ttttcttttc catcaggcca cctcgtctct
    27781 agattctaat atacacttct caatccattc atctatttca gactcaacaa aagcaatagc
    27841 ccgacttcca atttttacct gtttagggaa cctcccctga ctaataagac gataaatcca
    27901 tgctttgcta taaccagttc gcctttgaac ttcagagaga cgaattaatg aattgtaatt
    27961 agccatttat taatatcctg tactaatgac gcaataaccc cctcctgcaa cgaatggcga
    28021 gagttttatt tgcgtcaaat gtcgaatacg ccaaagacca caatatgaaa aacatattgc
    28081 ggtcttttat aaaagatagt cagattgttt tggtttgttt gctccacaag ggtagagcta
    28141 ccctgcattt cggcaggatc acgctattag gcgtgacatc cagtagtttt aaagaacaat
    28201 tgcgctttgt cagcgccaaa gcctgttaaa gaacattccg cttttcagca gcgtagaagg
    28261 ctcaatacac cttcgtttat aaaagagcga ttgcccttct ccagggctaa ctgttaaata
    28321 gcaatcctct gtgagttttt atcaatctac tcccctatac tttagtaaac ctctgtatac
    28381 ttgtccagtt gtttcatgcg tgtttttcaa acaccatatg caccacattt ccgccatgct
    28441 cgagagaatc catatagtcg gcataccatt gaagcatctc ccgccttcca tccagatatt
    28501 gcgcatggtt gtatgtgcca cgaattgagt tcttatcaac gtgagcgagc tgagtttcta
    28561 tccacgcagt gttatagccc tgctcatgca aaatcgtact catagtgtgc cggaacccat
    28621 gaccagttac acgtccagcg tagccaatgc gcttaaacac ttggtttatg ctggcctcac
    28681 tcattgtttt ccttggatca ttgcgcccgg gaaacataag agggtaattg cctgttattt
    28741 ctctaatctt cccaataagc gaaagagcct gctcagacaa tggcacaata tgaggccgcc
    28801 gcattttcat acgtgaagcg ggtatctccc agatagcctt gttgaaatca atttcatccc
    28861 ataatgcgcc acgtagttcg ccagttcgca agccggtgat aatcagtaga cgagccgcca
    28921 taacaaccaa tgcgcttcct gagtaactgg acaatgcctt gaaaaaatca ggtaattctt
    28981 tggctgtaag gaaagggtaa tgattagatt catggccttg catcgcgcta gtaaggtctg
    29041 gtgcagggtt atactctgcg cgaccagtga ctattgcata gcggaaaact tccccgcacc
    29101 gctgcctcac ttttttggct ttttctgtag cacctcgccc ctcgatgcgc cgcagcacat
    29161 tcagaagttc aagtggtttg atttcggcga ttggtttttt gccaatgtaa gggaacacat
    29221 ctttgttgaa ggcttcgagg atgtctgaag cataaccagc agaccatttt tttaatttgc
    29281 tgctgtgcca ctcaagggca atatctttga aggtgttgtt taactgcgtt tcccgggcaa
    29341 tcttttcctc tcgtttcgct tccatcggat cgataccacc agcgatacct cttttcgcat
    29401 cttcacgttt tgcccgagca tcggctagag taacctcagg atacacacct agtgccaata
    29461 gcttctcttt accagctaca cgatatttaa gtcgccagta tttacctcca ttaggtttta
    29521 ccaagagata caaaccgcca ccatcggcca gcttgtaagc cttctctttt ggcttggctg
    29581 tgtctatttg acgggcattg agtttcactt gggggtacct ccactaaacc gaacagcaaa
    29641 tacccccata agtaccccca tctgaccgta gattttgagg gactttagta gacgtcaaaa
    29701 gacgaacggg gctttaatac gcggattata atgggttttg aaagacttta gtagacttgg
    29761 ggagatgttt gaatggtgcc gataatagga gtcgaaccta cgaccttcgc attacgaatg
    29821 cgctgctcta ccaactgagc tatatcggcc ctgaaaggac atgttcacga acgtgaatca
    29881 cggtgggcaa ggttaaaact aaccgggcga tgcgtcaatg gccttgtgaa tcaaatggct
    29941 acttttgcat cacccggttt tatttacgca cgaatggtgt aatcaccaat gccgatccac
    30001 ttgtaagtgg tcagtgcttc cagccccatt gggccacgcg cgtggagttt ttgtgtgctt
    30061 accgccactt ccgcacccag accaaactgg ccgccgtcgg taaaacgcgt agaggcgtta
    30121 acgtaaacag cggacgaatc cacttcgtta acaaaacgct gggcgttgcg catatcgcgg
    30181 gtcaggatcg catcggagtg ttgtgtgccg tgttcacgaa tatgggcgat ggcatcgtca
    30241 agatcgctga cgattttgac gttcaaatct aatgacagaa actcatcgtc atactcttcg
    30301 gctttaacag caaccacctt cgcagggcct gcctgcaact gcgccagtgc agctgcatct
    30361 gcgtgtaatg tcacgccgct ttccgccatt tgtttgctta atgcgggcag gaagctatcg
    30421 gcgatgtttt tattcaccag caacgtttca accgtattac atgtgctcgg acgctgagtt
    30481 ttcgcgttga cgatcacttt taatgcttca gcgatctcta cactttcatc aacgtaaata
    30541 tggcatacgc ctataccacc tgtgatcacc gggattgtcg actgttcacg gcacagttta
    30601 tgcaaaccag cgccaccacg cgggatcagc atgtcgatgt atttatccat acgcagcatt
    30661 tcactgacca gcgcacggtc aggattatca atcgcctgca cggcacccgc cggtaagccg
    30721 caggatttca gggcgtcctg aatcaccgcc accgttgcag cgttagtgcg acacgtttct
    30781 ttgccaccgc gcaggatcac cgcattaccg gttttcaggc acagcgaagc gacatcaacc
    30841 gtcacgttcg ggcgcgcttc ataaatcacg ccaataaccc ccagcggtac gcgacgacgc
    30901 tcaagacgca ggccgctgtc cagtacgccg ccatcgatta cctgccccac cggatcggcg
    30961 aggttgcaca cctgacgtac atcgtcggca atgcctttca gccgtgcggg cgtcagtgcc
    31021 agacggtcaa gcatcgcttc gctaaggcca ttggctcgcg cgtcagcaac atcctgggcg
    31081 ttagcgttga ggatgatttc gctttgtgct tccagttcat cggcgatttt ttccagcacg
    31141 cgattttttt cgcggctgga gagttgcgct aatttatacg aggcttgctt cgcggcaatg
    31201 cccatttgtt ccagcatcag cctgctcctt aacgggtaat catgtcatca cggtgaacgg
    31261 caaccgggcc gtattcatat cccagtattg catcaatttc ttgcgagtgg tgtccggcaa
    31321 tacggcgtaa tgcatcgctg ttgtaacgac tgacgccgtg ggcgatatcg cggccttcga
    31381 ggttgcaaat gcggatgact tcaccacgcg agaaattgcc agtcacgctt ttaatgcctt
    31441 tcggcaacag ggagctgccg cgttccagaa tggcggcagt tgccccttca tctaccgtga
    31501 tttcacccgc cggcggcgca ccgaaaatcc agcgtttacg gttttcaagc ggagtcgcct
    31561 gggcatggaa cagcgtaccg acggaaatgc cttccatcac atcaccaata acgcccggct
    31621 tgctgcccgc ggcaataatg gtgtcgatac ccgcacggca agccacgtca gcggcctgca
    31681 atttggtact catgccgcca gttccgaggc ctgaaacgct gtcaccggca atcgcgcgca
    31741 gtgcgtcatc aatgccgtaa acatctttaa tcagttctgc ctgcggattg ctgcgcgggt
    31801 cagcggtata caaacctttt tgatcggtca gcagcaacag tttatcggca cccgcaagaa
    31861 tcgccgccag cgcagaaagg ttatcgttat cgccgacctt aatctctgcc gtagcgacag
    31921 catcgttctc attgattacc ggaacgatat tgttatcgag caacgctcgc agggtgtcgc
    31981 gggcgttcag gaagcgttca cggtcttcca tatcagcacg ggtcagcagc atttgcccga
    32041 cgtgaatgcc ataaatcgaa aacagctgtt cccacagttg aatcagtcga ctctgcccta
    32101 ccgccgccag cagttgtttc gaggcgatgg tcgctggcag ttccgggtaa cccaggtgct
    32161 cacgtccggc ggcgatcgcg cccgacgtca caataacaat ccgatgcccg gcggcatgta
    32221 actgcgcgca ctggcgaaca agttcaacga tatgggcacg gttcagacgg cgcgatccgc
    32281 ctgttagcac actggtgccg agttttacca ccagcgtctg gctgtcactc atgattctct
    32341 gccattcaat tttaggaaaa atgatatcaa acgaacgttt tagcaggact gtcgtcggtt
    32401 gccaaccatc tgcgagcaaa gcatggcgtt ttgttgcgcg ggatcagcaa gcctagcggc
    32461 agttgtttac gcttttatta cagatttaat aaattaccac attttaagaa tattattaat
    32521 ctgtaatata tctttaacaa tctcaggtta aaaactttcc tgttttcaac gggactctcc
    32581 cgctgaatat tcgcgcgtta attaaaatca ggaatgaaaa tgaaaaagag cactctggca
    32641 ttagtggtga tgggcattgt ggcatctgca tctgtacagg ctgcagaaat atataataaa
    32701 gacggtaata aactggatgt ctatggcaaa gttaaagcca tgcattatat gagtgataac
    32761 gccagtaaag atggcgacca gagttatatc cgttttggtt ttaaaggcga aacacaaatt
    32821 aacgatcaac tgactggtta tggtcgttgg gaagcagagt ttgccggtaa taaagcagag
    32881 agtgatactg cacagcaaaa aacgcgtctc gcttttgccg ggttgaaata taaagatttg
    32941 ggttctttcg attatggtcg taacctgggg gcgttgtatg acgtggaagc ctggaccgat
    33001 atgttcccgg aatttggtgg cgattcctcg gcgcagaccg acaactttat gaccaaacgc
    33061 gccagcggtc tggcgacgta tcggaacacc gacttcttcg gcgttatcga tggcctgaac
    33121 ttaaccctgc aatatcaagg gaaaaacgaa aaccgcgacg ttaaaaagca aaacggcgat
    33181 ggcttcggca cgtcattgac atatgacttt ggcggcagcg atttctccat tagtggggcc
    33241 tataccaact cagatcgcac caacgagcag aacctgcaaa gccgtggcac aggcaagcgt
    33301 gcagaagcat gggcaacagg tctgaaatac gatgccaata atatttatct ggcaactttc
    33361 tattctgaaa cacgcaaaat gacgccaata actggcggct ttgccaataa gacacagaac
    33421 tttgaagcgg tcgctcaata ccagtttgac tttggtctgc gtccatcgct gggttatgtc
    33481 ttatcgaaag ggaaagatat tgaaggtatc ggtgatgaag atctggtcaa ttatatcgac
    33541 gtcggtgcta cgtattattt caacaaaaat atgtcagcgt ttgttgatta taaaatcaac
    33601 caactggata gcgataacaa attgaatatt aataatgatg atattgtcgc ggttggcatg
    33661 acgtatcagt tttaatgaat attgccggat gtgatgcatc cggcacattt cactcacgcc
    33721 gttaacttca ccggctcgtc acgaaaatca tccgccggtt ccagcttcag attcagcgtc
    33781 gtcagcagtt cacgcagctt ctcgtgaaac tcacgcaggg tgtgctccag tcgttcaacc
    33841 acttcagtgt cttttaccgg aacactcttc cagtcgcctg ctttatcgaa cagaccaaac
    33901 tggtaactgt aggtaaaacg ggattcctgc gcttccagct ccatccacca gccccagaat
    33961 tcacgcactt ccggtgccgg tttcacgttg acgcatacag ccagacaatc gaaaaagaat
    34021 cgattatctt cgcacttacc ttcacgaata tacgggccta gtgcggtaaa ttttttgatc
    34081 aatctgctct tcgggtgtcc actcggtaac gtcattgcta tctcctgttg tgatgcaact
    34141 gttttaccaa attggcaaaa tttagcaaat ttttaacaca agcgtttttc gatccagtcg
    34201 gtgatttcct gaagaccttt gtcaaaattc cgatacaccg ggttaaatgg gatctctaat
    34261 aatttaccgt cagcagatga tgaggtgatt aagcgtgagt cctcttccgg gctgaacgga
    34321 tcgttcttcc agtagcctga taacattggc gttgggcagc gacgtcccag caatccttgc
    34381 acttttaatg aatagcgatt cagctccacg cgcaacgctt catcggaagc atcatgcatc
    34441 cccaaacgac tggccagaac gtcaagatac atttccggca cctgttgctg gcacttaaaa
    34501 tcactcaaca gggtatgaac taccggacca agacaggcaa ccgctttcag acgcggcgat
    34561 tcaaggtatg ccagacgcac ggcaacgtta gcgccgaaac ggaaaccaaa ggccgcgacg
    34621 cgagtgtgat ccacccacgg tacgttaggc agcgccttta agacgtgctg atgcaacagg
    34681 ctggagtcct gggtgagctt ccattttgaa gaaaagccca ccgacggcat atcaatagtc
    34741 agcatcgcaa tgccgcgcgg cgcaaaataa cgttcataca ggctgtaata gtccgtctgc
    34801 atcgcatcca gaccaccaca cattaatacc gtcgggaacg ggccatcgcc tttcggcata
    34861 tgcaaaaagc cggtgatggg cgcaccgccg ggtacggtaa actccatctg ccgcatcgtg
    34921 cccggtagac gctgagcggc ctcttcatag gcgcggtttg acaaagcctg cgcttgctcg
    34981 gccaggtcat ctcctttcag atgaggatag gcggcaatgt tgtacaacgt agccgcatgc
    35041 agccagtgac gaccactgag ttgcggatcg tcttccgcac aggctttttg ttgccacacc
    35101 atcgcctggg tggcccactc ataaatccag ttgccgccac ggtagccaat caccgtatcg
    35161 tataaatcat cgtcggtacg ttcggcatcg ctcatcacaa tacgtgcctg gacgtcgagg
    35221 atttcgcgtg ggtcaatgcc gcgccagatc cacatcagac ggttaatcat gcgataccag
    35281 tgagggatgg ttttaccatc aagggccgac tgcacaggcg gttgtgcgcc gtgattaaag
    35341 cggcggacta gcgtcgaggt ttcaggatgt ttaaagcggg gtttgaacag ggtttcgctc
    35401 aggtttgcct gtgtcatgga tgcagcctcc agaatactta ctggaaacta ttgtaacccg
    35461 cctgaagtta aaaagaacaa cgcccggcag tgccaggcgt tgaaaagatt agcgaccgga
    35521 gattggcggg acgaatacga cgcccatatc ccacggctgt tcaatccagg tatcttgcgg
    35581 gatatcaaca acatagtcat caaccagcgg acgaccagcc ggttttgcga agatggtgac
    35641 aaagtgcgct tttggataca tttcacgaat cgcaaccgca gtaccaccgg tatccaccag
    35701 gtcatcaata acgatgaagc cttcgccatc gccttctgcg cgtttcagca ctttaagctc
    35761 gcgctggttg tcgtgatcgt agctggaaat acaaacggta tcgacatgac gaatacccag
    35821 ttcacgcgcc agtaacgcac ccggtaccag accgccacgg cttacggcaa taatgccttt
    35881 ccattgttca gaaggcatca gtcggcttgc gagtttacgt gcatggatct gcaacatgtc
    35941 ccaggtgacg atgtattttt cgctcatgtg aagtgtccca gcctgtttat ctacggctta
    36001 aaaagtgttc gaggggaaaa taggttgcgc gagattatag agatctggcg cactaaaaac
    36061 cagtatttca catgagtccg cgtcttttta cgcactgcct ctccctgacg cgggataaag
    36121 tggtattctc aaacatatct cgcaagcctg tcttgtgttg acaacatttt ctgctaaccc
    36181 tgtgacctgc aatactgttt tgcgggtgat cgacaaggag acttaacgtg tctgaactgt
    36241 ctcaattatc tccacagccg ctgtgggata tttttgccaa aatctgttct attcctcacc
    36301 cgtcctatca tgaagagcaa ctcgctgaat acattgttgg ttgggcaaaa gagaaaggtt
    36361 tccatgtcga acgcgatcag gtaggtaata tcctgattcg taaacctgct accgcaggta
    36421 tggaaaatcg taaaccggtc gtcttacagg cccacctcga tatggtgccg cagaaaaata
    36481 acgacaccgt gcatgacttc acgaaagatc ctatccagcc ttatattgat ggcgaatggg
    36541 ttaaagcgcg cggcaccacg ctgggtgcgg ataacggcat tggtatggcc tctgcgctgg
    36601 cggttctggc tgacgaaaac gtggttcacg gcccgctgga agtgctgctg accatgaccg
    36661 aagaagccgg tatggacggt gcgttcggct tacagggcaa ctggttgcag gctgatattc
    36721 tgattaacac cgactccgaa gaagaaggtg aaatctacat gggttgtgcg gggggtatcg
    36781 acttcacctc caacctgcat ttagatcgtg aagcggttcc agctggtttt gaaaccttca
    36841 agttaacctt aaaaggtctg aaaggcggtc actccggcgg ggaaatccac gttgggctgg
    36901 gtaatgccaa caaactgctg gtgcgcttcc tggcgggtca tgcggaagaa ctggatctgc
    36961 gccttatcga tttcaacggc ggcacactgc gtaacgccat cccgcgtgaa gcctttgcga
    37021 ccattgctgt cgcagctgat aaagtcgacg tcctgaaatc tctggtgaat acctatcagg
    37081 agatcctgaa aaacgagctg gcagaaaaag agaaaaatct ggccttgttg ctggactctg
    37141 tagcgaacga taaagctgcc ctgattgcga aatctcgcga tacctttatt cgtctgctga
    37201 acgccacccc gaacggtgtg attcgtaact ccgatgtagc caaaggtgtg gttgaaacct
    37261 ccctgaacgt cggtgtggtg accatgactg acaataacgt agaaattcac tgcctgatcc
    37321 gttcactgat cgacagcggt aaagactacg tggtgagcat gctggattcg ctgggtaaac
    37381 tggctggcgc gaaaaccgaa gcgaaaggcg catatcctgg ctggcagccg gacgctaatt
    37441 ctccggtgat gcatctggta cgtgaaacct atcagcgcct gttcaacaag acgccgaaca
    37501 tccagattat ccacgcgggc ctggaatgtg gtctgttcaa aaaaccgtat ccggaaatgg
    37561 acatggtttc tatcgggcca actatcaccg gtccacactc tccggatgag caagttcaca
    37621 tcgaaagcgt aggtcattac tggacactgc tgactgaact gctgaaagaa attccggcga
    37681 agtaattatt tgatttgctg ccggatggcg tttaatcgcc ttccggcagt ttcatccttc
    37741 attatccttc gataaaagcc atccctgtaa atgtccgtcg cgggttgcca cgttcaatct
    37801 ggtgatggaa cattcgccgc tgcgatttca gcgccgcgct attttcctgt tgctgttgct
    37861 ccagcttcca ggcaatcagc aatcgtgcca gccgcttgtt agcatgctga ctacgctctg
    37921 actgaacctt cacgctaata ccggatgcca aatgcgtggc gcgtaccgcc gagtcggttt
    37981 tattgacatg ttgaccgccc ggccccgacg aacgcagcgt ctcataacgg attgcatccg
    38041 attgttcctg ctcatcagcg gtaaaacgcc caatgcccag aaaccagttt ttgcgcccat
    38101 gatgaggccg atacggactc ggacaaatcc actgaatagt gccacaccag ctttcgctta
    38161 atgcccatgc gttatcgcca tcgagagaaa ccagcgccga acgcagtgtg tcagagtagc
    38221 ggcccgtttc tgtttccagc accgttaccg cgacgtcttg ccgggtaaaa acgaccaaca
    38281 gagaagaacg ctgcgccaat cgggtagccg cgtccggggt gtaaatctgg catccccact
    38341 acgcgctgca tgttgggtaa atttgccgtg gtgtgtaatt gttggatcgc taaactctcg
    38401 atccacaggt catcagatgc gatggtaaat accgcatcgg ataagggacg aatatatttg
    38461 cccatgtacc attccattta tactcgtcat acttcaagtt gcatgtactg cgactgcgtt
    38521 cgttcacccc agtcacttac ttatgtaagc tcctggcgat tcactcgctt gtcgccttcc
    38581 tgcaactcga attatttaga gtatataaat ataaaaatca ggaaatggca gacgaatcca
    38641 gggcaagaaa aaaagaatta atcctggaaa ggtctgcaaa gagtcattga taaaggattt
    38701 gtcatgattt acctccttgc agtttgtgga atcagaaaac gcgcacatac caggcgggcg
    38761 ttattttcat tgcaagctgg atttaatgtt gcggtttata tcgcatataa aaattagtaa
    38821 accacgctcc ccggcattca acgcgctgct gcttaactgt ctgaaaacca taacgttcaa
    38881 aaaagggttt tgcggttatg cttgcgtcca ccgtaagttc ggattcagac ttaatcaaag
    38941 gttttaacaa agcgctggca accccacggc gggtgtattc agggtcaaca aataacatat
    39001 cgatataatg ttcaatgcgg gaaataaaac caaccggttg tgcattaatg atcgcaaccc
    39061 acacttgtga tttcgcgagt ttctccttcc agcgagattc gtcaatctgc gcccaggcgg
    39121 aaatttgttg tggtgaataa tgctgactgg cggtcatcgt aaccgctcta atgaaaatag
    39181 cgcatagttg ctgaaaatcg ccaggctgat agtttcttat ttgtatgtta ttcataatat
    39241 aaattcaaaa acgcatgcga aacgcttctg ccattttccc aattttatgc atttggttgt
    39301 tatctcgagc cagtttatga ggttcaggtt tcagaatggc aatgagcaac catgcttgct
    39361 catcaaacgc cccctgacaa tataccaaat gcgcttcgtc attcgttctg ctgaattggc
    39421 gcaactgtgg cggaaatgga ttattctcat ttgccagatg aatatgagca actcgctcaa
    39481 atttgattaa tggccaggta aaggagtcgt cgtagagtgc atcgcgacca aatatatctg
    39541 gcaaaacacc gtcacgctta taggaaataa aatccgccgt taacgcatca agttcctctg
    39601 ctgtaagttg caggcgaata agttttgttt tgaatacccg catccttatt ccttaaagtc
    39661 attgaaatca tcatccgtca tatcattaag atattgttca gcgcggcgtg taatttcctc
    39721 taatcttgca gcacttggac ggaagcgcgc ctttatgggc tttttctcct cttgttcagc
    39781 aagcatgtcc attaacgctt cgaatgcgct ggcacttaag agatatcctg cggggcgatt
    39841 attagaaaga accgcaaccg gttgatcaat aaagtattta gctgggtttt tacgtaactc
    39901 agtgatattg accgattttt cagcgagaat tcgatgcata cagtgatacc ctcataataa
    39961 tgcacaccag aatatacata atagtataca tcataatccc agcaccagtt gtctttccat
    40021 ttgcgggtca agcaacgtca catgcagccc caccagacgc acaccgcgcc cgccgcggcg
    40081 ttcatcccag gttttacgcg cggtggcgat tagatcagct ttattcagcc gcggccagac
    40141 gtgctcctgg gtggtttgct gaaaatcgtc gaactttaat ttcaccccct ggcgagcaat
    40201 cagtaaatca ggttttacct ttgccagacg gcgttcaagt tccggataca gccgctcgat
    40261 aatcgcttca cattcagacc agtgatgaat atcttccgcc atcgtgcgtt ccacgccgac
    40321 ggattttcgc aaccgttcgc tgttaacatc gcgttcgtca atcccctgac tacgctccca
    40381 caaaatgcgg ccaaatttgc caaagcgttt aagcagcatc accagatcac acttttgtac
    40441 atcaccgcag gtccgcagcc ccatcgcttc cagttttgcc gctgagactt tgccgacgcc
    40501 ggggattttt gccagcggta aggtttgtaa aaatgccgga acttctgccg gcgtaatcac
    40561 aaactggccg ttgggtttat tcatgtcgga ggcgattttg gcgagaaact ttactggtgc
    40621 cacgcccgca gacgccgtca gttgcagctc gttgaagatt gtctggcgga tttcctgggc
    40681 gatgagggtc gcagaaccgt ggcaatggac gctatcggtg acatcgagat aagcctcatc
    40741 cagtgacaac ggttcaatgc gcgaggtgta gcgcgagaag atttcacgga tatgatttga
    40801 ggcttctttg taggcgtcaa agcgccccgg aagcaaggtg agatgtgggc ataatttgag
    40861 cgccatccct gtcggcatag cgctacgtac gccaaattta cgcgcgggat aattggcggt
    40921 gctgatcacc ccccgacgtt cgcggctgcc gccaatagca atagggatat cgcgcagggc
    40981 gggattgtcg cgcatctcca ctgcggcgaa aaagcagtcc atatccacat gaatgatttt
    41041 acgcattgct cacctctcaa cactggtaaa gtatacagtg atttcagggt ttgagaaatg
    41101 cgtaaagatt cagcatttaa cgcgttcgct gcgaaagcac ctgctgctta tccagctttt
    41161 gcaccagcgg ctgcaccact ttatccccat gctgaccaaa gtattgatac agcgtatcgg
    41221 acgcactttt ggtcagcacc ataatctcaa tgcgccggtt gcccgcgctt tgcggatttt
    41281 tggaatccag cagcatctgg tccgccattg cgcttacctg catcacttta tcttccggca
    41341 ttccggcctc ttccagcacc cgacgagccg aaagcgcgcg gtcacccgaa aggttccagt
    41401 tgttgtagat attgtttttg taggccatcg catcggtatg cccggtaata ataattttat
    41461 tatcgagcga gtcgaacact ggcgcgagct ccaccagcag cgttttaaag aacggcataa
    41521 tcttcgcgct gccgcgttca aacatattgc ggttctggtc gtctttaatc agcacgcgta
    41581 atccctgggg aacaatctcc atctccagat tcgcttccat atgcgcatca cgggcaatgg
    41641 tgttgatact ggttgccagc tcaccaagct cggtggcgga tttcttcttc agcagcgccg
    41701 ttttctcatt cacatcacgc gcttttttct ccgtctcttc cggcaccgcc acggtggcag
    41761 gttttggcgg atgagacggg ctgattttat ttaacggcga cagcccacca ccgttaaaaa
    41821 tcgactgccc gtgcagcgcg gcgataatgc tttcacgctc ggatttactg acgctgttga
    41881 caatcaactt tattgtcgtc accaaagggg ccgagcgtat ttccgaggtt tctgcccgct
    41941 ttaccttaga cgcgatgccc ggcaaacaga tggcgattga cgccgatctt aacgccggat
    42001 tgatcaacca ggcgcaggcg caaacccggc gtaaagatgt tgccagcgag gccgatttct
    42061 acggcgcgat ggacggggca tcgaagtttg tgcgcgggga cgccatcgcc gggatgatga
    42121 ttctggcgat caacctgatc ggcggcgtct gtatcgggat cttcaaatac aacctgagcg
    42181 ccgatgctgc cttccagcag tatgtgctga tgaccatcgg cgacggcctg gtggcgcaga
    42241 tcccttccct gctgctctcc accgcggcgg cgattatcgt cacccgcgtc agcgacaacg
    42301 gcgatatcgc ccatgacgtg cgtaaccagc tgctggcaag cccgtcggtg ctctacaccg
    42361 ccaccgggat tatgttcgtg ctggcggtgg taccgggaat gccgcacctg ccgtttttgc
    42421 tgttcagcgc cctgcttggt tttaccggct ggcggatgag caaacagccg ctggcggcgg
    42481 aggcggaaga gaaaagcctc gaaacgctga cccgcaccat caccgaaacc agcgagcagc
    42541 aggtcagttg ggaaaccatt ccgctgatcg agcctatcag tttaagcctc ggttacaaac
    42601 tggtggcgct ggtggacaaa gcacagggta acccgctcac ccagcggatt cgcggcgtgc
    42661 ggcaggtgat ttctgacggc aacggcgtgc tgctgccgga gatccgcatt cgggaaaact
    42721 tccgccttaa gcccagtcag tacgccattt tcatcaacgg cataaaggct gatgaagcgg
    42781 atattccggc ggataaactg atggccctgc cctccagcga aacctacggc gagattgacg
    42841 gcgtgcaggg gaacgacccg gcgtacggga tgccggtcac ctggatccag gcggcgcaga
    42901 aagcgaaggc gctgaatatg gggtatcagg tgatcgacag cgccagcgtg atcgctaccc
    42961 atgtaaataa gattgtgcgc agctatattc ctgatttgtt taactatgat gatattacgc
    43021 agttgcataa ccgtttatcg tcgacggcac cgcgtctggc ggaagatttg agcgcggcgc
    43081 tcaattacag ccagttgctg aaagtgtacc gggcgctgct gaccgaaggc gtttccctgc
    43141 gcgatatcgt caccatcgcc accgtgctgg tcgccagtag cacggtgacg aaagatcata
    43201 ttctgctggc ggccgatgtg cgcctggcat tgcggcgcag cattacccat ccgttcgttc
    43261 gcaagcagga gctgacggtg tatacgctga ataatgagct ggaaaatctg ctgaccaacg
    43321 tggtgaatca ggcgcaacag ggcgggaaag tgatgctcga cagcgtgccg gtcgatccga
    43381 atatgctcaa ccagttccag agtacgatgc cacaggtgaa agagcagatg aaagcggcgg
    43441 ggaaagaccc ggtgctgctg gtgccaccgc agctgcgccc tttgctggcg cgttatgcaa
    43501 ggttgtttgc gccggggctg catgtgctgt cgtataacga agtgccggat gagctggagt
    43561 tgaagattat gggggcgttg atgtaagtat ccagcattgg tgcacaactg ccggatgcgg
    43621 cgtgaacgcc ttatccgtcc taccgttcag gcacaagttt gtaggcatga taagacgcgc
    43681 cagcgtcgca tcaggcatct gcgcataact gccggatgcg gcataaacgc cttatccggc
    43741 ctaccgatcc ggcacaagtt tgtaggcatg ataagacgcg ctagcgtcgc atcaggcatc
    43801 tgcgcacaat tatgaaatga tacgctcccc ggcactaaaa tccgttacgt cccccgccca
    43861 atcgatggga tataaccctc gcgcgacatc gcgatggaac gttgagaatg gccaatcact
    43921 cacttgcttt acccaaccat gctttactgg atttatataa atataatcaa catgatgcct
    43981 ataatctttg gtattgcgga tggcgtgctc ccaaaaacgt ggttgccaga tatttttcaa
    44041 tccacaagca tgggtaaatt gctttttaat ttcccgccag cgcgaggaaa aatcatcatc
    44101 gccttcaggt aatgtccaga tacagtgcat atgctctggc aaaacgaccc aggcgttgat
    44161 ttcaaaaggc ctgtctcgct taactttaat aatggcgtga cggagcatct ggtactgggt
    44221 ggtcaaaagt tggcttcgac gatttcgtaa attcaccgtg aaaaaccatg ttcccccctt
    44281 gatgtaataa cgacgatatt cagacatggc gactcctttt tctcaacggt aagaagaaaa
    44341 ggaaaggttg gcaatgaggt tgttttatat cgggaaagcg gctcgcaaat attcgcgggc
    44401 tcgtaggcat gataagacgc gccagcgtcg catcaggcac ctgcgtacaa ctgccggatg
    44461 cggcgtaaac gccttatccg tcctacaaaa tcgtctcttc cgtcaaaatc ctgcgcgcgc
    44521 ccaaaaaatg gtcctgccag aaaggttcgg ctaatcggct tatccgaatg gtttcgccgg
    44581 tacgtggcga ctcgataaat tgcccatcgc ccaaatacac gcccatatga tcggctatct
    44641 cgcggctgtg gatatggaaa aacagcaaat ctccccggcg caggtcgttg ttcgccacaa
    44701 tcgttgcccg gcgatagtgg tacatctcat tggccgtgcg cgggagctta gcctcaagga
    44761 tcttgttgta ggcataaaaa accaacccgc tacagtcaaa gcctttatca ggccgcgtac
    44821 cgccccagac gtaaggcttg ccaagctgct gctccaggcg gtgaatcgcc acttcggtaa
    44881 tgttatgcag atggtcgctg cttaaaaagt ggttgttttc cgccagcgcc tgccagcgtc
    44941 tgtcactcgc cttgagcgga gcaggaaacc attctggatg ctgttttatc tgctcccggt
    45001 tgtgctggcg tagcgccctt ttgctttcgg cattgccttc cacaatatag ctggcctgct
    45061 ttttcagatg agtttggtac tgttttaata aacgcgcacg gttttgcatc cgctggcggg
    45121 cggcgtagct gaaagagata tgtgatgtgg tggcgctggc aaatgaagaa aacggcaaac
    45181 aaatcaacag taatcccgac aatacaaagg atggaatcga cggcaaggac atactcaata
    45241 atggctggtc atgctttaat gttgcagtg
//
LOCUS       DACAOP010000028        44666 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.028, whole genome shotgun sequence.
ACCESSION   DACAOP010000028 DACAOP010000000
VERSION     DACAOP010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 44666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44666
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.028"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..1213
                     /locus_tag="IT892_001741"
     CDS             <1..1213
                     /locus_tag="IT892_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001381246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66-like element ISEc22 family transposase"
                     /protein_id="HAP3134967.1"
                     /translation="DEKRLLPAASCCPECGGSLSYLGEDAAEQLELMRSAFRVIRTVR
                     EKHACTQCDAIVQAPAPSRPIERGIAGPGLLARVLISKYAEHTPLYRQSEMYGRQGVE
                     LSRSLLSGWVDACCRLLSPLEEALQDYVLTDGKLHADDTPVPVLLPGNKKTKTGRLWT
                     YVRDDRNAGSTLAPAVWFAYSPDRKGIHPQTHLAGFSGVLQADAYAGFNELYRDGRIT
                     EAACWAHARRKIHDVHVRTPSALTEEALKRIGELYAIEAEIRGMTAEQRLAERQLKTK
                     PLLKSLESWLREKMKTLSRHSELAKAFAYALNQWPALTYYADDGWAEADNNIAENALR
                     MVSLGRKNYLFFGSDHGGERGALLYSLIGTCKLNGVEPESYLRYVLDVIADWPINRVG
                     ELLPLARSTAD"
     gene            complement(1256..1516)
                     /locus_tag="IT892_001742"
                     /pseudo
     CDS             complement(1256..1516)
                     /locus_tag="IT892_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418173.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1565..2032)
                     /locus_tag="IT892_001743"
     CDS             complement(1565..2032)
                     /locus_tag="IT892_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CbrB"
                     /protein_id="HAP3134968.1"
                     /translation="MSVSRRVIHHGLYFAVLGPLIGVLFLVLYIFFAKEPLVLWVIIH
                     PIFLLLSITTGAIPALLTGVMVACLPEKIGSQKRYRCLAGGIGGVVITEIYCAVIVHI
                     KGMASSELFENILSGDSLVVRIIPALLAGVVMSRIITRLPGLDISCPETDSLS"
     gene            complement(2099..2764)
                     /gene="yieH"
                     /locus_tag="IT892_001744"
     CDS             complement(2099..2764)
                     /gene="yieH"
                     /locus_tag="IT892_001744"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate phosphatase"
                     /protein_id="HAP3134969.1"
                     /translation="MSRIEAVFFDCDGTLVDSEVICSRAYVTMFQEFGITLDPEEVFK
                     RFKGVKLYEIIDIVSLEHGVTLAKTEAEHVYRAEVARLFDSELEAIEGAGALLSAITA
                     PMCVVSNGPNNKMQHSMGKLNMLHYFPDKLFSGYDIQRWKPDPALMFHAAKAMNVNVE
                     NCILVDDSVAGAQSGIDAGMEVFYFCADPHNKPIVHPKVTTFTHLSQLPELWKARGWD
                     ITA"
     gene            2929..4266
                     /locus_tag="IT892_001745"
     CDS             2929..4266
                     /locus_tag="IT892_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP3134970.1"
                     /translation="MSHQHTTQTSGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVY
                     IVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVV
                     VQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
                     LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLG
                     WMLGDVHYNGIVSAPPSVMTVVGHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVT
                     DKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAV
                     VVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAV
                     MMPFSFSITEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH"
     gene            complement(4320..4886)
                     /gene="yieF"
                     /locus_tag="IT892_001746"
     CDS             complement(4320..4886)
                     /gene="yieF"
                     /locus_tag="IT892_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent chromate oxidoreductase YieF"
                     /protein_id="HAP3134971.1"
                     /translation="MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIA
                     DIPLYDADVQQEEGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLP
                     DQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQT
                     GEVIDQGTLDHLTGQLTAFGEFIQRVKI"
     gene            complement(4908..5657)
                     /locus_tag="IT892_001747"
     CDS             complement(4908..5657)
                     /locus_tag="IT892_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134972.1"
                     /translation="MATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRG
                     LLAELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTEGECGLD
                     MELQRATRGFHSPHAPDNHTFSSNESLWISKQNDPNEARAQLITLRRSVLKLTGDVLN
                     DDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWSVAVTPTIEKLSVWELDGKHGWK
                     SLPDIHSRANNPTSRMMRFAQLSTVKAFSPN"
     gene            complement(5814..6773)
                     /gene="yidZ"
                     /locus_tag="IT892_001748"
     CDS             complement(5814..6773)
                     /gene="yidZ"
                     /locus_tag="IT892_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator YidZ"
                     /protein_id="HAP3134973.1"
                     /translation="MKKSITTLDLNLLLCLQLLMQERSVTKAAKRINVTPSAVSKSLA
                     KLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELA
                     AESPLMMIMLNALSKQIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSR
                     ELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHQTWNLDTFLRYPHISICWEQSDTWAL
                     DNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPL
                     PFDESQQKKLEVPFTLLWHKRNSHNPKIVWLRETIKNLYASMA"
     gene            complement(6748..7923)
                     /gene="mdtL"
                     /locus_tag="IT892_001749"
     CDS             complement(6748..7923)
                     /gene="mdtL"
                     /locus_tag="IT892_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtL"
                     /protein_id="HAP3134974.1"
                     /translation="MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAF
                     SVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQG
                     LGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLF
                     WAMAMMGIAVLMLSLFILKETRPAAPAASDKPRENSESLLNRLFLSRVVITTLSVSVI
                     LTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQV
                     LFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIA
                     QVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA"
     gene            complement(8055..9302)
                     /gene="tnaB"
                     /locus_tag="IT892_001750"
     CDS             complement(8055..9302)
                     /gene="tnaB"
                     /locus_tag="IT892_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity tryptophan permease TnaB"
                     /protein_id="HAP3134975.1"
                     /translation="MTDQAEKKHSAFWGVMVIAGTVIGGGMFALPVDLAGAWFFWGAF
                     ILIIAWFSMLHSGLLLLEANLNYPVGSSFNTITKDLIGNTWNIISGITVAFVLYILTY
                     AYISANGAIISETISMNLGYHANPRIVGICTAIFVASVLWLSSLAASRITSLFLGLKI
                     ISFVIVFGSFFFQVDYSILRDATSSTAGTSYFPYIFMALPVCLASFGFHGNIPSLIIC
                     YGKRKDKLIKSVVFGSLLALVIYLFWLYCTMGNIPRESFKVIISSGGNVDSLVKSFLG
                     TKQHGIIEFCLLVFSNLAVASSFFGVTLGLFDYLADLFKIDNSHGGRFKTVLLTFLPP
                     ALLYLIFPNGFIYGIGGAGLCATIWAVIIPAVLAIKARKKFPNQMFTVWGGNLIPAIV
                     ILFGITVILCWFGNVFNVLPKFG"
     gene            complement(9393..10808)
                     /gene="tnaA"
                     /locus_tag="IT892_001751"
     CDS             complement(9393..10808)
                     /gene="tnaA"
                     /locus_tag="IT892_001751"
                     /EC_number="4.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase"
                     /protein_id="HAP3134976.1"
                     /translation="MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSE
                     DVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQG
                     RGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFD
                     TGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAK
                     KYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPM
                     GGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYR
                     IAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIR
                     AVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIK
                     GLTFTYEPKVLRHFTAKLKEV"
     gene            complement(11029..11103)
                     /gene="tnaC"
                     /locus_tag="IT892_001752"
     CDS             complement(11029..11103)
                     /gene="tnaC"
                     /locus_tag="IT892_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase leader peptide"
                     /protein_id="HAP3134977.1"
                     /translation="MNILHICVTSKWFNIDNKIVDHRP"
     gene            complement(11346..12710)
                     /gene="mnmE"
                     /locus_tag="IT892_001753"
     CDS             complement(11346..12710)
                     /gene="mnmE"
                     /locus_tag="IT892_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAP3134978.1"
                     /translation="MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPR
                     YADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPG
                     LRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
                     EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMK
                     VVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRE
                     ASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVR
                     NKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRH
                     LQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSF
                     CIGK"
     gene            complement(12816..14462)
                     /gene="yidC"
                     /locus_tag="IT892_001754"
     CDS             complement(12816..14462)
                     /gene="yidC"
                     /locus_tag="IT892_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP3134979.1"
                     /translation="MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAA
                     GSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLET
                     SPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
                     FTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTF
                     RGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYT
                     ANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW
                     FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA
                     MRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAP
                     FALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW
                     FPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS"
     gene            complement(14465..14722)
                     /gene="yidD"
                     /locus_tag="IT892_001755"
     CDS             complement(14465..14722)
                     /gene="yidD"
                     /locus_tag="IT892_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAP3134980.1"
                     /translation="MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEA
                     LRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH"
     gene            complement(14686..15045)
                     /gene="rnpA"
                     /locus_tag="IT892_001756"
     CDS             complement(14686..15045)
                     /gene="rnpA"
                     /locus_tag="IT892_001756"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAP3134981.1"
                     /translation="MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGH
                     PRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALS
                     EALEKLWRRHCRLARGS"
     gene            complement(15062..15202)
                     /gene="rpmH"
                     /locus_tag="IT892_001757"
     CDS             complement(15062..15202)
                     /gene="rpmH"
                     /locus_tag="IT892_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAP3134982.1"
                     /translation="MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
                     SK"
     gene            complement(15432..15512)
                     /locus_tag="IT892_001758"
     CDS             complement(15432..15512)
                     /locus_tag="IT892_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134983.1"
                     /translation="MTIDKNWLNRSNKDPGRSLRFTHQPV"
     gene            15809..17212
                     /gene="dnaA"
                     /locus_tag="IT892_001759"
     CDS             15809..17212
                     /gene="dnaA"
                     /locus_tag="IT892_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAP3134984.1"
                     /translation="MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPN
                     RFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVA
                     QTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADN
                     PGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNA
                     IEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEIN
                     GVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVR
                     ELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVA
                     DLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREE
                     SHDIKEDFSNLIRTLSS"
     gene            17217..18317
                     /gene="dnaN"
                     /locus_tag="IT892_001760"
     CDS             17217..18317
                     /gene="dnaN"
                     /locus_tag="IT892_001760"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006177590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAP3134985.1"
                     /translation="MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSL
                     TGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSG
                     RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
                     ETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQI
                     GSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE
                     KFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCE
                     NVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL"
     gene            18317..19390
                     /gene="recF"
                     /locus_tag="IT892_001761"
     CDS             18317..19390
                     /gene="recF"
                     /locus_tag="IT892_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAP3134986.1"
                     /translation="MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIY
                     TLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDG
                     HKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQ
                     RNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTF
                     SFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKL
                     LMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISA
                     EHVIDMSDENSKMFTVEKGKITD"
     gene            19419..21833
                     /gene="gyrB"
                     /locus_tag="IT892_001762"
     CDS             19419..21833
                     /gene="gyrB"
                     /locus_tag="IT892_001762"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAP3134987.1"
                     /translation="MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVV
                     DNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGG
                     KFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET
                     EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY
                     EGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQR
                     DGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSS
                     QTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMT
                     RRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKI
                     LNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRT
                     LLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATL
                     HTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQ
                     TVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFI
                     TGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYK
                     GLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALK
                     AANIDI"
     gene            22064..22471
                     /locus_tag="IT892_001763"
     CDS             22064..22471
                     /locus_tag="IT892_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidB family protein"
                     /protein_id="HAP3134988.1"
                     /translation="MIIMGLFDEVVGAFLKGDAGKYQAILSWVEEQGGIQVLLEKLQS
                     GGLGAILSTWLSNQQGNQSVSGEQLESALGTNAVSDLGQKLGVDTSTASSLLAEQLPK
                     IIDALSPQGEVSPQANNDLLSAGMELLKGKLFR"
     gene            22586..23398
                     /gene="yidA"
                     /locus_tag="IT892_001764"
     CDS             22586..23398
                     /gene="yidA"
                     /locus_tag="IT892_001764"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAP3134989.1"
                     /translation="MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTG
                     RPYAGVHNYLKELHMEQPGDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSRE
                     VGSHFHALDRTTLYTANRDISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEP
                     AILDQAIARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAI
                     GDQENDIAMIEYAGVGVAMDNAIPSVKEVANFVTKSNLEDGVAFAIEKYVLN"
     gene            complement(23444..24100)
                     /locus_tag="IT892_001765"
     CDS             complement(23444..24100)
                     /locus_tag="IT892_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3134990.1"
                     /translation="MKLNFKGFFKAAGLFPLALMLSGCISYALVSHTAKGSSGKYQSQ
                     SDTITGLSQAKDSNGTKGYVFVGESLDYLITDGADDIVKMLNDPALNRHNIQVADDAR
                     FVLNAGKKKFTGTISLYYYWNNEEEKALATHYGFACGVQHCTRSLENLKGTIHEKNKN
                     MDYSKVMAFYHPFKVRFYEYYSPRGIPDGVSAALLPVTVTLDIITAPLQFLVVYAVNQ
                     "
     gene            24378..25067
                     /gene="dgoR"
                     /locus_tag="IT892_001766"
     CDS             24378..25067
                     /gene="dgoR"
                     /locus_tag="IT892_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-galactonate utilization transcriptional
                     regulator DgoR"
                     /protein_id="HAP3134991.1"
                     /translation="MTLNKTDRIVITLGKQIVHGKYVPGSPLPAEAELCEEFATSRNI
                     IREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVR
                     NLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNP
                     VLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMI
                     ASSTRRLKEIT"
     gene            25064..25942
                     /locus_tag="IT892_001767"
     CDS             25064..25942
                     /locus_tag="IT892_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HAP3134992.1"
                     /translation="MTARYIAIDWGSTNLRAWLYQGDHCLESRQSEAGVTRLNGKSPA
                     AVLAEVTTDWREEKTPVVMAGMVGSNVGWKVAPYLSVPACFSSIGEQLTSVGDNIWII
                     PGLCVSHDDNHNVMRGEETQLIGARALAPSSLYVMPGTHCKWVQADSQQINDFRTVMT
                     GELHHLLLNHSLIGAGLPPQENSADAFTAGLERGLNTPAILPQLFEVRASHVLGTLPR
                     EQVSEFLSGLLIGAEVASMRDYVAHQHAITLVAGTSLTARYQQAFQAMGCDVTAVAGD
                     TAFQAGIRSIAHAVAN"
     gene            25926..26543
                     /locus_tag="IT892_001768"
     CDS             25926..26543
                     /locus_tag="IT892_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HAP3134993.1"
                     /translation="MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQ
                     WEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGM
                     TVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPE
                     NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ"
     gene            26540..27688
                     /gene="dgoD"
                     /locus_tag="IT892_001769"
     CDS             26540..27688
                     /gene="dgoD"
                     /locus_tag="IT892_001769"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020077623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HAP3134994.1"
                     /translation="MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAA
                     VHELGDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPV
                     WQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGLIDNSRAV
                     DAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAE
                     YYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAE
                     AYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFS
                     MVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW"
     gene            27763..29100
                     /locus_tag="IT892_001770"
     CDS             27763..29100
                     /locus_tag="IT892_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3134995.1"
                     /translation="MVSGFAMPKIWRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICY
                     VDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIA
                     IFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFY
                     TSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKA
                     ELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVASTLWFFLT
                     WFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPII
                     CGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVF
                     NFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG"
     gene            complement(29097..30161)
                     /gene="cbrA"
                     /locus_tag="IT892_001771"
     CDS             complement(29097..30161)
                     /gene="cbrA"
                     /locus_tag="IT892_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418145.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin M resistance protein"
                     /protein_id="HAP3134996.1"
                     /translation="MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSK
                     PCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHA
                     FDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSM
                     VRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNSITNCYSWSISKDGYFIFGGAY
                     PMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAG
                     FISASSLEGISYALDSTDILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA
                     PALRKWIMRSGVAHIPQLKD"
     gene            30226..31476
                     /locus_tag="IT892_001772"
     CDS             30226..31476
                     /locus_tag="IT892_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3748 domain-containing protein"
                     /protein_id="HAP3134997.1"
                     /translation="MMAGPVLYQDRAMKQITFAPRNHLLTNTNTWTPDSQWLVFDVRP
                     SGASFTGETIERVNIHTGEVEVIYRASQGAHVGVVTVHPKSEKYVFIHGPENPDETWH
                     YDFHHRRGVIVEGGKMSNLDAMDITAPYTPGVLRGGSHVHVFSPNGERVSFTYNDHVM
                     HELDPALDLRNVGVAAPFGPVNVQKQHPREYSGSHWCVLVSKTTPTPQPGSDEINRAY
                     EEGWVGNHALAFIGDTLSPKGEKVPELFIVELPQDEAGWKAAGDAPLSGTETTLPAPP
                     RGVVQRRLTFTHHRAYPGLVNVPRHWVRCNPQGTQIAFLMRDDNGIVQLWLISPQGGE
                     PRQLTHNKTDIQSAFNWHPSGEWLGFVLDNRIACAHAQSGEVEYLTEHHANSPSADAV
                     VFSPDGQWLAWMEGGQLWITETDR"
     gene            complement(31478..31810)
                     /locus_tag="IT892_001773"
     CDS             complement(31478..31810)
                     /locus_tag="IT892_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HAP3134998.1"
                     /translation="MIRNVLLAFMICSGMTLLGGCSSVMSHTGGKEGTYPGTRASATM
                     IGDDETNWGTKSLAILDMPFTAVMDTLLLPWDVFRKDSSVRSRVEKSEANAQATNAVI
                     PPARMPDN"
     gene            32116..32529
                     /gene="ibpA"
                     /locus_tag="IT892_001774"
     CDS             32116..32529
                     /gene="ibpA"
                     /locus_tag="IT892_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpA"
                     /protein_id="HAP3134999.1"
                     /translation="MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDE
                     NHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLA
                     ENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN"
     gene            32641..33069
                     /gene="ibpB"
                     /locus_tag="IT892_001775"
     CDS             32641..33069
                     /gene="ibpB"
                     /locus_tag="IT892_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709512.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpB"
                     /protein_id="HAP3135000.1"
                     /translation="MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNH
                     YRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAEN
                     MEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS"
     gene            33265..34926
                     /locus_tag="IT892_001776"
     CDS             33265..34926
                     /locus_tag="IT892_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HAP3135001.1"
                     /translation="MSDIALTVSILALVAVVGLFIGNVKFRGIGLGIGGVLFGGIIVG
                     HFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVI
                     IGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMEMVDQMGMSY
                     AMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESSRTNGGALIKTINIRVENPNLHD
                     LAIKDVPILNGDKIICSRLKREETLKVPSPDTIIQLGDLLHLVGQPADLHNAQLVIGQ
                     EVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASGD
                     ISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVP
                     GFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKS
                     GGDFVNTLVNGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPP
                     ALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG"
     gene            complement(34923..35639)
                     /locus_tag="IT892_001777"
     CDS             complement(34923..35639)
                     /locus_tag="IT892_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP3135002.1"
                     /translation="MIYKSIAERLRIRLNSADFTLNSLLPGEKKLAEEFAVSRMTIRK
                     AIDLLVAWGLVVRRHGSGTYLVRKDVLHQTASLTGLVEVLKRQGKTVTSQVLIFEIMP
                     APPAIASQLRIQINEQIYFSRRVRFVEGKPLMLEDSYMPVKLFRNLSLQHLEGSKFEY
                     IEQECGILIGGNYESLTPVLADRLLARQMKVAEHTPLLRITSLSYSESGEFLNYSVMF
                     RNASEYQVEYHLRRLHPEKS"
     gene            35934..37550
                     /locus_tag="IT892_001778"
     CDS             35934..37550
                     /locus_tag="IT892_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312650.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP3135003.1"
                     /translation="MLSQIQRFGGAMFTPVLLFPFAGIVVGLAILLQNPMFVGESLTD
                     PNSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVMVSFLTWNYFI
                     NAMGMTWGSYFGVDFTQDAVAGSGLTMMAGIKTLDTSIIGAIIISGIVTALHNRLFDK
                     KLPVFLGIFQGTSYVVIIAFLVMIPCAWLTLLGWPKVQMGIESLQAFLRSAGALGVWV
                     YTFLERILIPTGLHHFIYGQFIFGPAAVEGGIQMYWAQHLQEFSLSAEPLKSLFPEGG
                     FALHGNSKIFGAVGISLAMYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFI
                     SPLLFAVHAVLAASMSTVMYLFGVVGNMGGGLIDQVLPQNWIPMFSNHADMMLTQIAI
                     GLCFTLLYFVVFRTLILQFNMCTPGREDAEVKLYSKAEYKASRGQTTAAEPKKELDQA
                     AGILQALGGVGNISSINNCATRLRIALHDMSQTLDDEVFKKLGAHGVFRSGDAIQVII
                     GLHVSQLREQLDSLINSHQSAENVAITEAV"
     gene            37550..38364
                     /locus_tag="IT892_001779"
                     /pseudo
     CDS             37550..38364
                     /locus_tag="IT892_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312649.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="inactive 6-phospho-alpha-glucosidase"
     gene            complement(38361..39254)
                     /locus_tag="IT892_001780"
     CDS             complement(38361..39254)
                     /locus_tag="IT892_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418136.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP3135004.1"
                     /translation="MNGKLQSSDVKNETPYNIPLLINENVISSGISLISLWHTYADEH
                     YRVIWPRDKKKPLIANSWVAVYTVQGCGKILLKNGEQITLHGNCIIFLKPMDIHSYHC
                     EGLVWEQYWMEFTPTSMMDIPVGQQSVIYNGEIYNQELTEVAELITSPEAIKNNLAVA
                     FLTKIIYQWICLMYADGKKDPQRRQIEKLIATLHASLQQRWSVADMAATIPCSEAWLR
                     RLFLRYTGKTPKEYYLDARLDLALSLLKQQGNSVGEVADTLNFFDSFHFSKAFKHKFG
                     YAPSAVLKNTDQHPTDASPHN"
     gene            39421..41136
                     /locus_tag="IT892_001781"
     CDS             39421..41136
                     /locus_tag="IT892_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HAP3135005.1"
                     /translation="MNSLQILSFVGFTLLVAVITWWKVRKTDTGSQQGYFLAGRSLKA
                     PVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRGI
                     ATIPDFLEERYDKTTRIIIDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQISHG
                     AAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFM
                     QGIEQLTTVHAEKLNSIGGPTDPLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLA
                     EGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPMVGFFG
                     AVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVLV
                     APWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITI
                     NYLVKFDFHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDMKPWKNVKIAS
                     IGILFAMIGVYAGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSWRHRHDPAVTFTPD
                     GKDSL"
     gene            41133..42626
                     /locus_tag="IT892_001782"
     CDS             41133..42626
                     /locus_tag="IT892_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HAP3135006.1"
                     /translation="MKRPNFLFVMTDTQATNMVGCYSGKPLNTQNIDSLAAEGIRFNS
                     AYTCSPVCTPARAGLFTGIYANQSGPWTNNVAPGKNISTMGRYFKDAGYHTCYIGKWH
                     LDGHDYFGTGECPPEWDADYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETF
                     TWAHRISNRAVDFLQQPARADEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKA
                     QDDLANKPEHHRLWAQAMPSPVGDDGLYHHPLYFACNDFVDDQIGRVINALTPEQREN
                     TWVIYTSDHGEMMGAHKLISKGAAMYDDITRIPLIIRSPQGERRQVDTPVSHIDLLPT
                     MMALADIEKPEILPGENILAVKEPRGVMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLV
                     LNLFTSDELYDRRNDPNEMHNLIDDIRFADVRSKMHDALLDYMDKIRDPFRSYQWSLR
                     PWRKDARPRWMGAFRPRPQDGYSPVVRDYDTGLPTQGVKVEEKKQKF"
     gene            complement(42673..43122)
                     /locus_tag="IT892_001783"
     CDS             complement(42673..43122)
                     /locus_tag="IT892_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135007.1"
                     /translation="MGIIAQNKISSLGMLFGAIALMMGIIHFSFGPFSAPPPTFESIV
                     ADKTAEIKRGLLAGIKGEKITTVEKKEDVDVDKILNQSGIALAIAALLCAFIGGMRKE
                     NRWGIRGALVFGGGTLAFHTLLFGIGIVCSILLIFLIFSFLTGGSLV"
     gene            43230..43577
                     /locus_tag="IT892_001784"
     CDS             43230..43577
                     /locus_tag="IT892_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidH family protein"
                     /protein_id="HAP3135008.1"
                     /translation="MKISRLGEAPDYRFSLANERTFLAWIRTALGFLAAGVGLDQLAP
                     DFATPVIRELLALLLCLFSGGLAMYGYLRWLRNEKAMRLKEDLPYTNSLLIISLILMV
                     VAVIVMGLVLYAG"
     gene            43567..43929
                     /locus_tag="IT892_001785"
     CDS             43567..43929
                     /locus_tag="IT892_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF202 domain-containing protein"
                     /protein_id="HAP3135009.1"
                     /translation="MPDSRKARRIADPGLQPERTSLAWFRTMLGYGALMALAIKHNWH
                     QAGMLFWISIGILAIVALILWHYTRNRNLMDVTNSDFSQFHVVRDKFLISLAVLSLAI
                     LFAVTHIHQLIVFIERVA"
     gene            43926..44423
                     /locus_tag="IT892_001786"
     CDS             43926..44423
                     /locus_tag="IT892_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAP3135010.1"
                     /translation="MTGSQVIDAEEDRHKLVVEYKDALQPADFYHNFKQRGIRSVQLI
                     PYLEFDDRGDLTAASVTAELWGKFLIALFECWVRADISRISIELFDATLQKWCGSENP
                     QPRCDCQACDWHRLCPHARQETPDSVLCAGYQAFYSYSAPHMRVMRDLIKQHRSPMEL
                     MTMLR"
     gene            complement(44431..>44666)
                     /locus_tag="IT892_001787"
     CDS             complement(44431..>44666)
                     /locus_tag="IT892_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418129.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135011.1"
                     /translation="PLATSGAMEPFPFLAGTAGALVGGLQNIGSGVLASLSAMLPQTG
                     QGSLGLLMTLMGLLIVLCWLPLATRMSHQGQPV"
BASE COUNT        10686 a        11359 c        11826 g        10795 t
ORIGIN      
        1 cgatgaaaaa cggctgctgc cggcagcgtc atgctgcccg gaatgtggag gctcgctgag
       61 ctatctgggt gaggatgccg ctgaacagct ggagctgatg cgcagcgcct tccgggttat
      121 ccggactgta cgtgaaaagc atgcctgtac tcagtgcgat gccatcgtgc aggcccccgc
      181 gccttcacgg cccatcgagc ggggtatcgc aggaccgggg ctgctggccc gcgtgctgat
      241 ctcaaagtat gcagagcaca ccccgctgta ccgccagtct gaaatgtacg gccgccaggg
      301 cgtggagctg agtcgttcac tgctgtcggg ctgggtggat gcatgctgcc ggctactgtc
      361 accgctggaa gaagcgcttc aggactatgt gctgactgac ggtaagctcc atgctgatga
      421 cacgcctgtc ccggtgctgt tgccaggcaa taagaaaacg aagaccgggc ggttatggac
      481 ctacgttcgt gacgaccgta acgccgggtc aacgctggcg ccggcggtgt ggttcgctta
      541 cagcccggac agaaaaggca tccatccgca gacccatctt gcggggttca gtggtgtact
      601 gcaggcggat gcatacgccg ggttcaacga gctgtaccgg gatggccgga taacggaagc
      661 cgcctgttgg gctcacgccc gccgtaaaat ccacgatgtg cacgttcgca ccccgtcagc
      721 cctgacggag gaagcgctga aacggatcgg cgaactgtac gccatcgagg cagagataag
      781 gggaatgacg gcggagcagc gccttgccga acgtcagttg aaaacgaaac cgctgctgaa
      841 atccctggaa agctggctgc gtgaaaagat gaaaaccctg tcgcgacact cagaactggc
      901 gaaagcgttc gcatacgccc tgaaccagtg gccggcgctg acgtactatg cagatgatgg
      961 ctgggctgag gcggacaata acatcgctga aaatgcgttg cggatggtca gtctgggccg
     1021 caaaaactac ctgttcttcg gttcggatca tggaggagag cggggagcgc tgctgtacag
     1081 cctgatcggg acgtgcaaac tgaacggagt ggagccagaa agctacctcc gctatgtcct
     1141 tgacgtcata gccgactggc cgataaaccg ggtcggcgaa ctgctccccc tggcgcgtag
     1201 cactgccgac tgaataacac atccccgtca atacggttct tgctgcacgc ttaccatcat
     1261 actcaaattc aacaccttct atgctggcat catcctgaaa actacctgca aacttttcag
     1321 cagcagaacc gtccgcaata caccacggac agagatgttc aacttcatca acgcaataaa
     1381 agggacccga gtaataaact gacgtctgtt gttcacagca atcgcactct acggttttat
     1441 cctgttcaaa tgcgcctgtt tccagtggct tgggatgata tttgaattgg ggtaacggcc
     1501 tgatattttg agtcatagaa acatcctgtc tgcttttgag tagcccaaag ataaagtatc
     1561 ccgcttaact taaagagtct gtttcaggac atgaaatatc caatccgggt agacgggtaa
     1621 tgattctgct catcaccaca cctgccagca atgcaggaat gatgcggaca acgagactgt
     1681 caccagaaag aatgttttca aacaactccg aggaagccat gcccttaata tgtacaataa
     1741 ctgcacaata gatctcggtg ataacgacgc cacctatgcc accagccaga caacgataac
     1801 gtttctgtga cccgatcttt tccggcagac aggcaaccat tacaccggtt aacaacgcag
     1861 gaatagctcc cgtagttatc gacaataaga gaaaaattgg atgtattatc acccaaagaa
     1921 ccagcggttc ttttgcgaag aatatgtaga ggacaagaaa cagaacacca attaacggtc
     1981 ctaaaactgc aaaataaagt ccgtgatgta ttacccgacg tgaaacagac atatcaaact
     2041 ccctttactt acctttgagc gccaatttaa gcggggtaag tgaagggagt gtgaagaact
     2101 atgccgtaat atcccaacca cgcgctttcc acagttcagg taactgcgaa agatgggtaa
     2161 aggtggtgac tttcgggtga acgatcggct tattgtgcgg gtcggcgcag aagtagaaca
     2221 cttccatacc tgcgtcgata ccagattgtg caccggcaac tgagtcatca accagaatgc
     2281 agttttctac atttacattc atcgcttttg ccgcatggaa cattaacgcc gggtctggct
     2341 tccagcgctg aatatcgtag ccgctgaaca gtttatccgg gaagtagtgc aacatattca
     2401 gcttgcccat agaatgctgc attttgttat ttgggccgtt agataccaca cacattggcg
     2461 cagtgatcgc tgacaggagc gctccagccc cttcgatggc ttccagttct gaatcgaaca
     2521 gccgagcgac ttctgcacgg taaacgtgtt cagcttctgt tttcgctaac gtaacaccat
     2581 gttcaaggga aacaatatcg ataatttcgt acagttttac acctttgaaa cgtttgaata
     2641 cctcttcagg atcgagcgta ataccaaatt cctgaaacat cgttacatat gcgcgagagc
     2701 aaatgacttc actgtcgacc agcgtaccgt cgcagtcgaa aaataccgct tctatccggg
     2761 acatgccttt cctttttaat cagtttaacg ttttcgtaga gccgatttgc gcaacgcaat
     2821 cgttgccgta taagtaaatc caataaaaaa gtctctcaca aacgcgccta ttgtcgcatt
     2881 ttggtatacg atagcgacgg attttccctc cttgttcgga aatagataat gagtcatcaa
     2941 cataccaccc agacttctgg tcaggggatg ctggaacgcg tgtttaaact gcgcgaacat
     3001 ggcacgacgg cacggaccga agtgatcgcc ggttttacca ccttcctgac gatggtttac
     3061 atcgtttttg ttaacccgca aattcttggc gttgctggca tggataccag cgccgtcttc
     3121 gtcactacct gtctgatcgc tgcattcggc agtattatga tgggactgtt tgctaacctg
     3181 ccagttgcac tggcacccgc tatgggcctg aatgcgttct tcgcttttgt cgttgtacag
     3241 gcgatgggct tgccgtggca ggtcgggatg ggcgcaatct tctggggcgc gataggtctg
     3301 ctgttactga cgattttccg cgttcgctac tggatgatag ccaacattcc ggtgagtctg
     3361 cgtgtgggta ttaccagcgg tatcggtctg ttcattggca tgatggggct gaaaaacgca
     3421 ggtgtgattg tcgctaaccc ggaaacgctg gtgagcatcg gtaatctgac ttctcacagc
     3481 gtacttctgg gtatcctcgg cttcttcatc attgctattc tggcctcgcg caacattcac
     3541 gcagcggtgc tggtttctat cgtggtgacg acgctgctgg gctggatgct gggtgatgtg
     3601 cactacaatg gcatcgtttc tgcgccgccg agcgtaatga cagttgtggg tcatgtagat
     3661 ttagccgggt cgtttaacct cgggctggca ggggtgattt tctctttcat gttggtcaac
     3721 ttgtttgact cctccggtac gctgattggc gtgaccgata aagcaggtct ggcggatgag
     3781 aaggggaaat tcccgcgcat gaagcaggcg ctgtatgtcg acagtatctc ttccgtgacc
     3841 ggttcgttta tcggtacttc ttccgttacg gcttatattg agtcctcttc cggcgtatcg
     3901 gttggcggtc gtaccggtct gacggcagtg gttgttggtc tgctgttcct gctggttatc
     3961 tttctgtcgc cgctggcggg gatggtgcca ggctacgctg cagctggtgc gctgatttac
     4021 gttggcgtgc tgatgacttc cagtctggca cgcgtgaact ggcaggatct tactgaatct
     4081 gttccggcgt ttattaccgc cgtgatgatg ccgttcagct tctcgattac cgaaggtatc
     4141 gcgctgggct ttatctccta ctgcgtgatg aaaatcggta ccggacgtct gcgtgatcta
     4201 agcccgtgcg taatcatcgt tgcgctgctg tttatcctga agattgtctt tatcgacgct
     4261 cactaaaatc gatagcgcgt taaaaacccg ccatgcatga ttgctggcgg gttttttatt
     4321 tagatcttaa ctcgctgaat aaactcacca aatgcggtca attgcccggt caggtggtcc
     4381 agcgtaccct gatcaatcac ttctccggtt tgcggatcaa ctttgttctg aatcacgccg
     4441 cccataaatt ccggcttgtt catcaccatt gcatcgagga aaaccagaat ctggcgcagg
     4501 tgatactgac agcgcgcgcc gccaatcacg cccattgagc tggtctgaat caataccggt
     4561 ttaccggcca gcggttgatc cggcaggcgg gaaagccagt cgatggcatt tttcagccca
     4621 cccggtaccg agtagttata ttccggcgtg acgatcacca caccgtcagc ctgacggatc
     4681 tgttccgcca gagcttcaac cgttgctgga aaaccttctt cctgctgtac gtcagcgtca
     4741 tacaagggaa tgtcggcaat ggatggtaac gcattgactt ccatgctcgc cggagcaatt
     4801 ttcggcaggg tacgtgcaac catgccatta aatgagcctt tgcgcaggct ccccagtaac
     4861 gtaaccacct gcaatttttc agacatgatg actcctgtgg ttgtctatca atttggcgaa
     4921 aaagccttca cggtagagag ttgggcaaaa cgcatcatcc ggctggtagg attgttggcg
     4981 cggctgtgaa tatccggcag gcttttccag ccgtgtttgc catctaactc ccagacactg
     5041 agcttttcaa tcgtgggcgt gaccgccacg gaccacacca gcacgtcttc cgcgtcgcat
     5101 aacgcttcta catgatttac atgagcacat ttcaggcgtc cggcaatggg cagcagctgc
     5161 agatcgcgcg gatcgtcatt caaaacatca ccggttagtt ttagcacgct tcggcgcagc
     5221 gtgatgagct gcgcccgcgc ttcgttagga tcgttttgtt tactgatcca tagcgattca
     5281 ttgctggaaa aggtgtggtt atcgggcgcg tgtgggctat gaaacccgcg cgtcgcacgc
     5341 tgtagttcca tatcgaggcc acattcacct tcggttgtta acgccacgcc aaccatattc
     5401 ccggcatagg aaatggaaaa cgaaggcaaa tttttatcac tgaaaaccgg tttacctttc
     5461 ggcagggtga cgatttccgg caattcgcca atgccataca gcatgaacat cagttctgcg
     5521 agtaaacctc tggacgccag aaaacggctt tgacgatgag ggggaatgtt tcgggcttct
     5581 tgatgacact gggaggggag acgaacagaa atcagatgtc cttccgttaa aatccctcgg
     5641 gcaaagtgag tcgccatttt tcgctccatg cttaatggtc cattatgaat acaagagtaa
     5701 tcatttactg gaatgatgga cagactaaag cggctaaaag ttcgattcag acaagcttat
     5761 tacaactttt ttacatttta ttgtgaaatt gggtcgcgtt tcatacgatt cggttatgcc
     5821 atcgacgcgt aaaggttttt aatggtttcc cgtaaccaga cgatcttcgg attatggctg
     5881 ttccgtttat gccacagcag ggtaaaagga acttccagct ttttttgctg gctttcgtca
     5941 aacgggagag gaagagcaac caacggcagt tgatggagtt gattgtagta ctgacagtag
     6001 cgcggcgcgg tcgccagtag cagattgtcg ggttgcgctg ccataaacag tgactgctcg
     6061 aattccggca ggctcatagc aatcgtgcgt tcgcgtccca gctcctgtaa cacattgtcc
     6121 agcgcccagg tatcgctctg ttcccagcaa atgctgatat gcggataacg taagaaggtg
     6181 tccagattcc acgtttgatg cagtgccgga tgatctttgc gtaaccagac gcagggcaca
     6241 tcactaaaca gcacttcata atcaatggct aacggtagcg agcttaacag ctcccgcgag
     6301 cgaggatggc tttcgcgacc ggaaaaaccg atatccactt caccacgagt aatggcatct
     6361 aaggaatcgt aatcccagtt acgtaatttg atggtcgcct gcgggtaacg ttggtagatc
     6421 tgtttcgaca gcgcattaag catgatcatc atcagcggtg attccgccgc cagctcaaac
     6481 ttcaggccgc gcggtgtctg gtggtgcggt ttatccagca gcaggttgct catttgcatc
     6541 cactccgcca gattttgctc catgctgacc atcagcggtg tgggcgacag acccagcggt
     6601 gagttcacaa agagcgggtc gtcaaaccac gctcttaact ttgccagcga cttactcacc
     6661 gccgaaggtg tcacgtttat ccgcttcgcc gctttggtta cgctgcgctc ctgcatcagc
     6721 agttgcagac aaagcagcag attgagatca agcgtggtga tggatttctt catgagcggc
     6781 aacggggcgt ccaggcgcga cgaacataat cagcaacagg ctcactatgc tacaggcaat
     6841 cagaatcccg atcagcatat tccatgcgcc gataccaacc accgctgcca gccaaatcca
     6901 cagtgacgaa ccgcaaacct gcgcaatacc taaggtcgag ctggctacgc ccgcgcgtaa
     6961 tgaaaacggc cctaacgcct gactcatcgc cacaccaaaa cctaccgaga aaccggcgca
     7021 aatcagcgtg ataccaaaca gagaaaccgc atgggaaggt gaaacggcaa gagtgatccc
     7081 cgccgccagg aataacacct gcgaggtgat catcaacgta cgtggcttaa aaattcccag
     7141 cgcaaatggc gtggagaatg aaacggtcat gctgacgcca gcggtcagcg ccataatggt
     7201 ggcgtattca ccgcgctcaa accccatgat ttccatcagc aataccggtg acgtgttgac
     7261 gaaagtgagg atcaccgaaa cgctgagggt ggtgataaca acacggctga ggaataaacg
     7321 gttaagcagc gactcgctat tttctcgtgg tttatccgaa gctgcggggg ccgctgggcg
     7381 cgtttctttt aaaataaaca aagacaacat cagtaccgcg atgcccatca ttgccatcgc
     7441 ccagaacaga ctctgccacg ggaatttaag cataatcaga tgtccgagca ctggcgctaa
     7501 caccggaatg atgcaggtaa taccgttgag taatgacagc actttagccc gacgtcgatc
     7561 atccagcgtg tcgcgcaaaa tagcgaacgc cactacgtaa caacagcctg cgcccaaccc
     7621 ctgtagaaat cggcctgcaa gaaataacgt gctggtttca gccagtgaac agaacaccga
     7681 ggcaataata aatagcgccg cgccgggtat ggcgaccggc tttctccctg aacgatcggc
     7741 cactttaccg gcaaataaca tcgcagctgc catccccgcc agatatacgg agaacgcaat
     7801 atgcaactgc gcttcgctgg cattgagatc ggcggcgatg cgcggtaaac caacgaggta
     7861 catatcaatc ccggcgggat aaagtaaaac cagggcaaaa ctacaaatca aaaagcggga
     7921 catgggctaa agcgtcctga tagtaaggtg acgcaaagca tacgtggtga aggaggatca
     7981 ggcgagttgc catttggaca taagtgattt cctgagaggc aagaagccag cgaatggctg
     8041 gcttcttgaa ggatttagcc aaatttaggt aacacgttaa agacgttgcc gaaccagcac
     8101 aaaatcacgg ttataccaaa gagaatgaca atcgccggaa taagattgcc gccccagacc
     8161 gtgaacatct gattgggaaa cttcttgcga gctttgattg caagcactgc gggaataatg
     8221 accgcccaga tggtggcgca cagcccggca ccgccgatcc cgtaaataaa gccgttcggg
     8281 aagatcagat acaacaacgc aggtggcagg aaggttaaca gcacggtttt gaaacgcccg
     8341 ccgtgggagt tatcaatctt aaacaggtcc gccagataat cgaacaaccc cagcgtgaca
     8401 ccaaagaacg aactggcaac agctaagtta gagaacacca gcaggcaaaa ctcgataatg
     8461 ccgtgctgtt tggtgccgag gaacgatttc accagcgaat caacgttgcc gcctgaggat
     8521 ataatcacct taaagctttc tcgcggaata ttccccatgg tgcaatagag ccagaagaga
     8581 taaatcacca gcgccagcag cgaaccaaat accacgcttt tgattaactt atctttgcgt
     8641 tttccatagc aaataatcag gctgggaata ttgccgtgga aaccaaatga cgccagacac
     8701 accggcaaag ccataaagat atacgggaag taagacgttc ccgcagtgga gctggtggcg
     8761 tcgcgcagaa tggagtaatc gacctggaag aaaaaagaac caaacacgat cacaaaggag
     8821 ataatcttca gcccgaggaa caatgaggta atacgactgg cggctaacga acttaaccac
     8881 aatacgctgg caacgaaaat ggctgtgcag atcccgacaa tacgtggatt agcgtgataa
     8941 cccaaattca ttgatatcgt ttcactaatg atcgcaccat tagcagagat ataggcataa
     9001 gtgaggatat agagaacgaa ggcaacggta ataccgctga taatgttcca ggtgttaccg
     9061 attaaatctt tggtgatggt gttaaaactg gagccgacgg gataatttaa atttgcttct
     9121 aataacaata acccggaatg aagcattgaa aaccaggcaa tgataaggat aaaggcaccc
     9181 cagaaaaacc aggcaccggc aagatcaaca ggtaaagcaa acatacctcc accaattact
     9241 gtacctgcta taaccataac accccaaaat gcagagtgct ttttttcagc ttgatcagtc
     9301 atgatgccac ctttagagga aggctatttt tgttattgag gatgtagggt aagagagtgg
     9361 ctaacatcct tatagccact ctgtagtatt aattaaactt ctttaagttt tgcggtgaag
     9421 tgacgcaata ctttcggttc gtacgtaaag gttaatcctt taatattcgc cgcgttctct
     9481 ttcacatgtt taaaggcttc aataatgaag tccatatgtg tttgagtata tgttgcgcgc
     9541 ggaatggtta aacgcagcag ttcagccggg catggcagtt gtttaccggt tttcggatcg
     9601 cggcctaaca ggaaagagcc aatttctacc gcacggatac cggcgacttt atacagctcg
     9661 caggccagcg cctgtgccgg gaactggtct gccgggatat gcggcaacag tttaccggca
     9721 tcaacgaatg ccgcgtgacc gcccgcctgc tggcagacaa cgccaatctc ttccagacca
     9781 tcgaccagat actgtacctg cgcgatacga taagccagcc agtcgagatt catgccgtca
     9841 tacagaccta ccgccagacg ctccatcgcg ccgccttcca ggccgccata tgtcgggaag
     9901 ccttcctgca ccacgcaaag ggttctgcac tcggtgtaca catcaaagaa gctgtcgtct
     9961 ttcatgcaca gcaggccgcc catcggcacc atcgcatctt tcttggcgga catcgccagc
    10021 atatcggcat atttgtaggt ttcgcgggtg atctgctcga tggtccagtc tttgtattct
    10081 gcttcacgct gcttgatgaa ataggcgttt tcagcaaagc gcgcggagtc cattaccacc
    10141 ggaatatcgt atttcttcgc gatgctgtac atcgctttta agtttgccag tgaaaccggc
    10201 tgaccacctg cagagttact ggtgatggtt gcaacgatat acggcacgtt attcggacca
    10261 acttcttcaa taccgcgttc taatccctca aggtcaaagt tgcctttaaa gtcgtaacgc
    10321 acgcccgtat cgaaggcttc tttgatatag acgttacgca cggtacagcc gttgatctgg
    10381 ctatggccct gcgtggtatc aaagaaatag ttagagaacg ccaccatttt gctgcgatcc
    10441 aggccttttt cctgctcgcg ttttttaatc agtaccggaa tatagatttg ctctgcgcca
    10501 cggccctggt gagtcggaat ggtgtattga taaccaaaga tatttttcac tgactcggct
    10561 aacgcatagt agctacgact gccgctgtag gcttcgtcgc cgcgcatcat cgcagcctgc
    10621 atgctctgcg tcaccgcccc ggtgccgctg tcggtcagta aatcgataaa cacatcttcg
    10681 ctatccagca ggaacgggtt cataccggat ttaataattg cctcttcacg ataagcgcga
    10741 gtggtacgtt ttactggctc aataacacga atgcggaacg gttcagggag atgtttaaag
    10801 ttttccatta cataatcctt catttatttt aattacagtg atccctgtga atattacatc
    10861 tgctataccg attaattcgc cagatatata tgcaagcacc atcatttact aaaacaagta
    10921 aataaacgag agatgacctt tgcaaaaggc aaaattaaga tatagcaaac caatagatca
    10981 cattgaatct aatcggtttg gctctggtga tggctacaga agggcaaatc aagggcggtg
    11041 atcgacaatt ttgttgtcaa tattgaacca ttttgaggtc acacatatat gtaagatatt
    11101 cataatgcac ttatcctcgc aagacacgag gctacattat tacactcaga gtttttgtct
    11161 attctgaaat tgtttaaatg tgaatcgaat cacaatcgtt cggggagcaa tattaaatgc
    11221 tttttttaaa gattataaat tacgtaagaa ttttaatgtt taaaaaaagg gttgaggaat
    11281 aacaggagtg gtaacaatga agcgaagccg catctgacag tcagaatgcg gcttcgtaag
    11341 cgcggttact taccaataca gaagctggag aaaatccgcc ccagcaggtc gtctgaagta
    11401 aattccccgg tgatttcgct taagttctgc tgtgccagac gcaactcttc cgccagcagt
    11461 tcacctgccc aggctcccaa cagttgcgct ttgccctgtt gtagatgttc cgctgcctgt
    11521 tccagcgcct gtaggtggcg acgacgcgcc aggaagccgc cttccatgtt ggtgtcaaag
    11581 cccatgctct gtttgagatg gttacgcagc acgtccacgc cttcaccagt ccttgccgag
    11641 agacgaatta acgcgtgacc gttcacttca ctcattccca gcgtttcgcc ggtgatatcg
    11701 gctttattgc gcaccacggt gatcggcagt ttcgctggca gacgggcaat aaattccggc
    11761 cagatctctg ccggatccac ggcgtctgtt gtggtgccat cgaccataaa cagcacgcgg
    11821 tcggcctgtt caatttcctg ccacgcgcgc tcgataccaa tacgttctac ttcgtcactg
    11881 gcttcacgta gcccggcggt atcgatgata tgcagcggca ttccgtcaat gtggatatgc
    11941 tcacgcagca cgtcacgcgt agttccggcg atatcggtta cgattgccgc ttcacgcccc
    12001 gccagcgcgt ttaacaggct cgatttaccg gcgttaggac gtccggcaat caccactttc
    12061 atcccttcgc gcaacaaact accctgacgt gcttcagcac gcactgcatc aagatcggca
    12121 ataacgtcat tgagctgggc ttcaattttt ccgtcggaga ggaaatcgat ctcttcatcg
    12181 gggaaatcaa ttgccgcttc gacgtaaatg cgcaagtggg tgagggcttc taccagatga
    12241 ttaacccgtg cggagaatgc gccttgcagc gagttaagtg ccgaacgggc cgcctgttcc
    12301 gaactggcgt cgataagatc ggcaatcgcc tcggcctggg ctaagtcaag tttatcgtta
    12361 agaaacgcgc gttcggaaaa ctcaccaggg cgagcaatcc gcaggccggg aatggtcaga
    12421 atgcgtttta acagcaggtc gaggatcacc ggaccgccat gaccttgcag ttccagcaca
    12481 tcttcgccgg tgaacgagtt cgggccaggg aaccatagcg caatcccctg atcgagcacg
    12541 ctgccgtcgg cgtctttaaa cggaagataa tcggcgtagc gcggcttagg cagtttaccc
    12601 agcacggttt cggcaacttc acgggctttg aagccggaga tgcgcaggat gccaacgccg
    12661 ccacgtcccg gaggcgtggc ctgggctacg atagtgtcat tatcgctcat gatgttcctg
    12721 ttgctttgtg tggcggatgc gcggtgctta tccgccctac gaaaagaaaa aaggcggtca
    12781 actgaccgcc cttattttag cgaaaactca ccgaatcagg attttttctt ctcgcggcta
    12841 tgcaggccac gtttttccag accacggtaa atcagctgct gctgaataat ggttaccagg
    12901 ttgctgacga tatagtacag caccagacct gacgggaacc acaggaagaa cacggtgaag
    12961 atgaccggca taaaggtcat gatcttctgc tgcatcgggt cggtcactgt ggtcggcgac
    13021 atcttctgaa tgaagaacat cgttacgccc atcaggatcg gcaggatgta gtacgggtcc
    13081 tgtgccgaca ggtcgtggat ccacagtgca aacggtgcct gacgcagttc aacggaaccc
    13141 atcagcatgt agtacaacgc caggaagatt ggcatctgga tcagcagcgg gaagcagccg
    13201 cccagcgggt taaccttctc agctttgtac agcgccatca tttcctggct gatacgctgt
    13261 ttgtcatcgc ccagacgctc acgcattgcc tgaatcttcg gctgcaacat acgcatcttc
    13321 gccatggagg tgtactgcgc tttggtcagc gggtacatga tgccacgaac gataaaggtg
    13381 atgatgataa tggagaagcc ccagttaccc acaaagctat ggatccattt cagcagtttg
    13441 aacagcggct gagagatgaa ccacaaccaa ccgtaatcaa cggtcagatc caggtgcgga
    13501 gcaacagctg ccattttgtc ctggatttcc gggccaaccc acagggtgct gttcatcgcg
    13561 ccagtctgac caggctgaac cagtaccggc tgagatttat agccgatagc ggcgatgccg
    13621 ttacccagat tagcggtata gaagttgttg gtaccgtcgt tatgcgggat ccacgccgtc
    13681 gcgaaatact gttgcagcat cgccacccaa ccacctttcg aagagatgtt caggttttcg
    13741 ttatcggcaa tggtatcgaa cttgtatttc tcatacttct cgtcaggcgt ggagtacgcc
    13801 gcgccacgga aggtgtgcag tgcgaagttg ctgcttccgg tatcgagatg cggtggcaga
    13861 gtgatggatt gcttcaactg accaaacgag gagatttcca gcggtttctc gccagcgttc
    13921 tgcacgttgt agttgacgtt gacagcgtaa tcaccacgtt tcaggacaaa cgttttggta
    13981 aacgtgttgc ctgccgcgtc ggtatacgtc atcggcacct gcagttcgtt ttgaccttca
    14041 gccagcacat aagcgtcttt ttcaacgtta tacagcggac gcgggccgtt agccgggtta
    14101 tccgggccat cacgaccggt cagaccgctc tgtgcctgat aaataaactg cggtgaagtt
    14161 tccaacagct ggaacggctg ggtagagttc agctctttcg ggtaagcagg cagcagagct
    14221 tgctcaacat caccaccacg ggtgttgatg gtcagatcaa gcacgtcggt cttaaccgag
    14281 atcagtttcc cctggccact ggccggtacg ccctggtcgg cggcgctacc cgctgcggtg
    14341 gtcgttgtct gcgtggtctg ttgggcctga ggttgcgggt ttttatcctg ctcccaggct
    14401 tgccagatca tgaaagacac gaacagcaaa gcgatgacta aaagattgcg ttgcgaatcc
    14461 atcgttagtg ttctctggta tcaaatggtc cgggcgggac gggatcgtca ccaccagggt
    14521 gtaaagggtg gcattttaat acgcgtttca ccgtcaacca actgcctttt atcactccaa
    14581 acctgcgcaa tgcctcaatt ccgtagcttg aacaggttgg agtgaaacga caatgcggcc
    14641 cgagtagcgg actaatcagg cgttgataga cccgaatgag ggctatcagg acccgcgagc
    14701 caggcgacag tggcggcgcc ataatttttc caacgcttcc gagagagcac ggttatcgag
    14761 gtcggcaacc ccttttttcg ccaccaccac gaaatccata gccgggagtt catgttggcg
    14821 cagacggaag ctttcacgcg tcagacgttt aatccgattg cgttcatggg cgcgtcgaac
    14881 gtttttcttg gcgactgtaa gaccgatacg gggatgcccc agcgaattca ggcggccgag
    14941 aatggtaatt tgcggcgtgc cagcccgttg tggctgctgg aagacgaatg tgaattgact
    15001 gggagttaac aagcgtaact ccctgggaaa tgcgagctta accactcagg ggttagcttt
    15061 attacttaga aacggtcaga cgagcgcggc ctttagcacg acgacgtgcc agaacctgac
    15121 gaccattttt agtagccata cgagcacgga agccgtgaga acggttgcgc ttcagtacag
    15181 acggttgaaa agtgcgtttc atggcgattt ctacctaaac ttgaataaat tcaatggctt
    15241 tattggatat ccgccgaaaa atgaaacgat ggacaccgaa gccatgggtg attaaagagg
    15301 ccggattgta ataattgtac actccggagt caattctctt tccttattta ccgcgctttt
    15361 ccgcaccttt tcgcagggaa aatgtacgac ctcacaccag tggaaaccag catggcgcgc
    15421 cgggtggagg attatacggg ctgatgggta aagcgcaagg atcgtcctgg atctttatta
    15481 gatcgattaa gccaattttt gtctatggtc attaaatttt ccaatatgcg gcgtaaatcg
    15541 tgcccgcctc gcggcaggat cgtttacact tagcgagttc tggaaagtcc tgtggataaa
    15601 tcgggaaaat ctgtgagaaa cagaagatct cttgcgcagt ttaggctatg atccgcggtc
    15661 ccgatcgttt tgcaggatct tgatcgggca tataaccgca gacagcggtt cgtgcgtcac
    15721 cctcaagcag ggtcttttcg acgtacgtca acaatcatga atgtttcagc cttagtcatt
    15781 atcgactttt gttcgagtgg agtccgccgt gtcactttcg ctttggcagc agtgtcttgc
    15841 ccgattgcag gatgagttac cagccacaga attcagtatg tggatacgcc cattgcaggc
    15901 ggaactgagc gataacacgc tggccctgta cgcgccaaac cgttttgtcc tcgattgggt
    15961 acgggacaag taccttaata atatcaatgg actgctaacc agtttctgcg gagcggatgc
    16021 cccacagctg cgttttgaag tcggcaccaa accggtgacg caaacgccac aagcggcagt
    16081 gacgagcaac gtcgcggccc ctgcacaggt ggcgcaaacg cagccgcaac gtgctgcgcc
    16141 ttctacgcgc tcaggttggg ataacgtccc ggccccggca gaaccgacct atcgttctaa
    16201 cgtaaacgtc aaacacacgt ttgataactt cgttgaaggt aaatctaacc aactggcgcg
    16261 cgcggcggct cgccaggtgg cggataaccc tggcggtgcc tataacccgt tgttccttta
    16321 tggcggcacg ggtctgggta aaactcacct gctgcatgcg gtgggtaacg gcattatggc
    16381 gcgcaagccg aatgccaaag tggtttatat gcactccgag cgctttgttc aggacatggt
    16441 taaagccctg caaaacaacg cgatcgaaga gtttaaacgc tactaccgtt ccgtagatgc
    16501 actgctgatc gacgatattc agttttttgc taataaagaa cgatctcagg aagagttttt
    16561 ccacaccttc aacgccctgc tggaaggtaa tcaacagatc attctcacct cggatcgcta
    16621 tccgaaagag atcaacggcg ttgaggatcg tttgaaatcc cgcttcggtt ggggactgac
    16681 tgtggcgatc gaaccgccag agctggaaac ccgtgtggcg atcctgatga aaaaggccga
    16741 cgaaaacgac attcgtttgc cgggcgaagt ggcgttcttt atcgccaagc gtctacgatc
    16801 taacgtacgt gagctggaag gggcgctgaa ccgcgtcatt gccaatgcca actttaccgg
    16861 acgggcgatc accatcgact tcgtgcgtga ggcgctgcgc gacttgctgg cattgcagga
    16921 aaaactggtc accatcgaca atattcagaa gacggtggcg gagtactaca agatcaaagt
    16981 cgcggatctc ctttccaagc gtcgatcccg ctcggtggcg cgtccgcgcc agatggcgat
    17041 ggcgctggcg aaagagctga ctaaccacag tctgccggag attggcgatg cgtttggtgg
    17101 ccgtgaccac acgacggtgc ttcatgcctg ccgtaagatc gagcagttgc gtgaagagag
    17161 ccacgatatc aaagaagatt tttcaaattt aatcagaaca ttgtcatcgt aaacctatga
    17221 aatttaccgt agaacgtgag catttattaa aaccgctaca acaggtgagc ggtccgttag
    17281 gtggtcgtcc tacgctaccg attctcggta atctgctgtt acaggttgct gacggtacgt
    17341 tgtcgctgac cggtactgat ctcgagatgg aaatggtggc acgtgttgcg ctggttcagc
    17401 cacacgagcc aggagcgacg accgttccgg cgcgcaaatt ctttgatatc tgccgtggtc
    17461 tgcctgaagg cgcggaaatt gccgtgcagc tggaaggtga acggatgctg gtacgctccg
    17521 ggcgtagccg tttttcgctg tctaccctgc cagcggcgga tttcccgaac ctcgatgact
    17581 ggcagagtga agtcgaattt accctgccgc aggcaacgat gaagcgtctg attgaagcga
    17641 cccagttttc tatggcgcat caggacgttc gctattactt aaatggtatg ctgtttgaaa
    17701 ccgaaggtga agaactgcgc accgtggcaa ccgacggcca ccgtctggcg gtctgttcaa
    17761 tgccaattgg tcaatctttg ccaagccatt cggtgatcgt accgcgtaaa ggcgtgattg
    17821 aactgatgcg tatgctcgac ggcggcgaca atccgctgcg cgtacagatt ggcagcaaca
    17881 acattcgcgc ccacgttggc gactttatct tcacctccaa actggtggat ggtcgcttcc
    17941 cggattatcg ccgcgttctg ccgaagaacc cggacaaaca tctggaagct ggctgcgatc
    18001 tgctcaagca ggcgtttgct cgcgcggcga ttctctctaa cgagaaattc cgcggcgtac
    18061 gtctttatgt cagcgaaaac cagctgaaaa tcaccgccaa caacccggaa caggaagaag
    18121 cggaagagat cctcgacgtt acctatagcg gtgcggagat ggaaatcggc ttcaacgtca
    18181 gttatgtgct ggatgttctg aacgcgctga aatgcgaaaa cgtccgcatg atgctgaccg
    18241 attcggtttc cagcgtgcag attgaagatg cggccagcca gagcgcggct tatgttgtca
    18301 tgccaatgag actgtaatgt ccctcacccg cttgttgatc cgcgatttcc gcaacattga
    18361 aaccgcggat ctcgccttat ctcccggctt taactttctg gtaggtgcca acggcagtgg
    18421 caaaaccagc gtgctggaag ccatctatac gctcggccat ggtcgggcgt ttcgcagttt
    18481 gcagattggt cgcgtcattc gccatgagca ggaggcgttt gttctccacg ggcgattaca
    18541 gggcgaagag cgcgagacag cgattggctt aaccaaagac aaacagggcg acagcaaagt
    18601 ccgcatcgac ggtacagacg ggcataaggt cgcggaactg gcgcacctga tgccaatgca
    18661 gttgataacg ccagaagggt ttactttact caacggcggc cccaaataca gaagagcatt
    18721 cctcgactgg ggatgctttc acaacgaacc cggatttttc accgcctgga gcaatctcaa
    18781 gcgattgctc aagcagcgca atgcggcgct gcgccaggtg acacgttacg aacagctacg
    18841 cccgtgggat aaagagctga tcccgctggc ggagcaaatc agcacctggc gcgcggagta
    18901 tagcgccggt atcgcggccg atatggctga tacctgtaag caatttctcc ctgagttttc
    18961 tctgactttc tctttccagc gcggctggga gaaagagaca gaatatgctg aggtgctgga
    19021 acgtaatttt gaacgcgatc gccagctaac ctacaccgcg cacggcccgc acaaagcgga
    19081 cttacgcatt cgcgccgacg gtgcgccggt ggaagatacc ttatcgcgtg ggcagcttaa
    19141 gctgttgatg tgcgccttac gtctggcgca aggagagttc ctcacccgtg aaagcgggcg
    19201 gcggtgtctc tacctgatag atgattttgc ctctgagctt gatgatgagc gtcgcgggct
    19261 gcttgccagc cgcttaaaag cgacgcaatc acaggtcttt gtcagcgcga tcagtgctga
    19321 acacgttata gacatgtcgg acgaaaattc gaagatgttt accgtggaaa agggtaaaat
    19381 aacggattaa cccaagtata aatgagcgag aaacgttgat gtcgaattct tatgactcct
    19441 ccagtatcaa agtcctgaaa gggctggatg cggtgcgtaa gcgcccgggt atgtatatcg
    19501 gcgacacgga tgacggcacc ggtctgcacc acatggtatt cgaggtggta gataacgcta
    19561 tcgacgaagc gctcgcgggt cactgtaaag aaattatcgt caccattcac gccgataact
    19621 ctgtctctgt acaggatgac gggcgcggca ttccgaccgg tattcacccg gaagagggcg
    19681 tatcggcggc ggaagtgatc atgaccgttc tgcacgcagg cggtaaattt gacgataact
    19741 cctataaagt gtccggcggt ctgcacggcg ttggtgtttc ggtagtaaac gccctgtcgc
    19801 aaaaactgga gctggttatc cagcgcgagg gtaaaattca ccgtcagatc tacgaacacg
    19861 gtgtaccgca ggccccgctg gcggttaccg gcgagactga aaaaaccggc accatggtgc
    19921 gtttctggcc cagcctcgaa accttcacca atgtgaccga gttcgaatat gaaattctgg
    19981 cgaaacgtct gcgtgagttg tcgttcctca actccggcgt ttccattcgt ctgcgcgaca
    20041 agcgcgacgg caaagaagac cacttccact atgaaggcgg catcaaggcg ttcgttgaat
    20101 atctgaacaa gaacaaaacg ccgatccacc cgaatatctt ctacttctcc actgaaaaag
    20161 acggtattgg cgtcgaagtg gcgttgcagt ggaacgatgg cttccaggaa aacatctact
    20221 gctttaccaa caacattccg cagcgtgacg gcggtactca cctggcaggc ttccgtgcgg
    20281 cgatgacccg taccctgaac gcctacatgg acaaagaagg ctacagcaaa aaagccaaag
    20341 tcagcgccac cggtgacgat gcgcgtgaag gcctgattgc ggtcgtttcc gtgaaagtgc
    20401 cggacccgaa attctcctcc cagaccaaag acaaactggt ttcttctgag gtgaaatcgg
    20461 cggttgaaca gcagatgaac gaactgctgg cagaatacct gctggaaaac ccaaccgacg
    20521 cgaaaatcgt ggttggcaaa attatcgatg ctgcccgtgc ccgtgaagcg gcgcgtcgcg
    20581 cgcgtgaaat gacccgccgt aaaggtgcgc tcgacttagc gggcctgccg ggcaaactgg
    20641 cagactgcca ggaacgcgat ccggcgcttt ccgaactgta cctggtggaa ggggactccg
    20701 cgggcggctc tgcgaagcag gggcgtaacc gcaagaacca ggcgattctg ccgctgaagg
    20761 gtaaaatcct caacgtcgag aaagcgcgct tcgataagat gctctcttct caggaagtgg
    20821 cgacgcttat caccgcgctt ggctgtggta tcggtcgtga cgagtacaac ccggacaaac
    20881 tgcgttatca cagcatcatc atcatgaccg atgcggacgt cgacggctcg cacattcgta
    20941 cgctgctgtt gaccttcttc tatcgtcaga tgccggaaat cgttgaacgc ggtcacgtct
    21001 acatcgctca gccgccgctg tacaaagtga agaaaggcaa gcaggaacag tacattaaag
    21061 acgacgaagc gatggatcag taccagatct ctatcgcgct ggacggcgca acgctgcaca
    21121 ccaacgccag tgcaccggca ttggctggcg aagcgttaga gaaactggta tctgagtaca
    21181 acgcgacgca gaaaatgatc aatcgtatgg agcgtcgtta tccgaaagca atgctgaaag
    21241 agcttatcta tcagccgacg ttgacggaag ctgacctttc tgatgagcag accgttaccc
    21301 gctgggtgaa cgcgctggtc agcgaactga acgacaaaga acagcacggc agccagtgga
    21361 agtttgatgt tcacaccaat gctgagcaaa acctgttcga gccgattgtt cgcgtgcgta
    21421 cccacggtgt ggatactgac tatccgctgg atcacgagtt tatcaccggt ggcgaatatc
    21481 gtcgtatctg cacgctgggt gagaaactgc gtggcttgct ggaagaagat gcgtttatcg
    21541 aacgtggcga gcgtcgtcag ccggtagcca gcttcgagca ggcgctggac tggctggtga
    21601 aagagtcccg tcgcggcctc tccatccagc gttataaagg tctgggcgag atgaacccgg
    21661 aacagctgtg ggaaaccact atggacccgg aaagtcgtcg tatgctgcgc gttaccgtta
    21721 aagatgcgat tgctgccgac cagttgttca ccacgctgat gggcgacgcc gttgaaccgc
    21781 gccgtgcgtt tattgaagag aacgccctga aagcggcgaa tatcgatatt taatggcgct
    21841 aaccatgcga gcgtgcctga tgcgctacgc ttatcaggcc tacgaaaatc ttgcaatata
    21901 ttgaattttc atgattttgt aggccggata aggcgttcac gccgcatccg gcaagaagct
    21961 ataagaaaag ggcggagatc atctccgccc tttttatttc tgcaatccgc aattatcatc
    22021 ccgcaaatct atactttttg ggtcaacacg taacgcttta caggtgatta tcatggggct
    22081 ttttgatgaa gttgtcggtg cctttctgaa aggcgatgcg gggaaatatc aggctatttt
    22141 aagttgggtt gaggagcagg gcggcattca ggtgctgctg gaaaaactgc aaagtggcgg
    22201 cttaggggcc attctctcaa cctggctgag taatcaacag ggcaatcaat cggttagtgg
    22261 cgagcaactg gaatcggcgc tcggcacaaa tgcggtgtcc gatctcgggc aaaaacttgg
    22321 cgtggatacc agtacagctt ccagtttact ggcagaacaa ttgccgaaga ttattgatgc
    22381 gctctcaccg caaggtgaag tgtcaccaca agccaataac gatctgcttt ccgcaggcat
    22441 ggaactgctg aaagggaaac tcttccgcta agcaaaaagg gagcacgcaa cgcgcgttgc
    22501 atcccccttt tccctcgggt gttgtactga tttttgagcg gaatcgcgtt agcatgggtc
    22561 aggaaccaat ctacctgggg aactcatggc tattaaactc attgctatcg atatggatgg
    22621 cacccttctg ctgcccgatc acaccatttc acccgccgtt aaaaatgcga ttgccgcagc
    22681 tcgcgcccgt ggcgtgaatg tcgtgctaac gacgggtcgc ccgtatgcag gtgtgcacaa
    22741 ctacctgaaa gagctgcata tggaacagcc gggcgactac tgcattactt ataacggcgc
    22801 gctggtacag aaggccgctg atggtagcac cgtggcgcaa actgctctca gctatgacga
    22861 ctatcgtttc ctggaaaaac tctctcgcga agtcggttct catttccacg ccctggaccg
    22921 caccacgctg tacaccgcca accgtgatat cagctactac acggtgcatg aatccttcgt
    22981 tgccaccatt ccgctggtgt tctgcgaagc ggagaaaatg gaccccaata cccagttcct
    23041 gaaagtgatg atgattgatg aacccgccat cctcgaccag gctatcgcgc gtattccgca
    23101 ggaagtgaaa gagaaatata ccgtgctgaa aagtgcgccg tacttcctcg aaatcctcga
    23161 taaacgcgtt aacaaaggta cgggggtgaa atcactggcc gacgtgttag gtattaaacc
    23221 ggaagaaatc atggcgattg gcgatcagga aaacgatatc gcaatgattg aatatgcagg
    23281 cgtcggtgtg gcgatggata acgctattcc ttcagtgaaa gaagtggcga actttgtcac
    23341 caaatctaac cttgaagatg gcgtggcgtt tgctattgag aagtatgtgc tgaattaatc
    23401 tgtgggcggg caaacagcat aaacgcgttt gcccgcttac tgattattgg tttactgcat
    23461 atacaaccag aaattgcagc ggtgcagtaa tgatgtccag cgtaacagtc actggcagta
    23521 atgctgcgga aacaccatcc ggaatgcctc tgggtgaata gtattcataa aatcgcactt
    23581 taaatggatg gtagaacgcc atcacctttg agtaatccat gtttttattt ttctcatgga
    23641 ttgtgccttt taggttttcc agtgacctgg tacagtgttg aacaccacag gcaaaaccat
    23701 aatgcgttgc cagtgccttt tcttcttcgt tattccagta gtagtaaagc gatattgtgc
    23761 cggtaaattt ctttttcccc gcatttaaaa caaatcttgc gtcatcggca acctgaatat
    23821 tgtgccggtt aagtgctgga tcattgagca tcttaacgat gtcatcggca ccatcagtga
    23881 taaggtaatc cagcgattcc cctacaaaaa catagccttt tgttccatta ctatcttttg
    23941 cctgcgatag cccagtgatg gtgtctgact gcgattgata ctttcctgaa ctaccctttg
    24001 cggtatggga aaccagagca tacgagatac agcctgaaag catcagcgcc agtgggaata
    24061 aaccggcagc cttaaaaaat cccttaaaat tcaacttcat gattaatcct ttaaacgagt
    24121 agctaagccg ttgaaagcat actcttcttt ccctcctgtt tagcgcctga tatccctttt
    24181 cagatttctg cccgacgcat gtcatttttt tatgcattgt tctttttgtg atctaaattg
    24241 tagtacaaca atataagttt gtactacatt acacgcacgg caaacgcgaa cgtcatcacg
    24301 ctggtactac aaagttgccg cgttatgcat cgatcggggt aaagtagaga agaacataca
    24361 gagcacaagg actctccatg actctcaata aaaccgatcg cattgtcatt acgctgggta
    24421 aacagatcgt tcacggcaaa tacgtgccag gctcgccgct tccggctgag gcggaactct
    24481 gtgaggagtt tgcaacctcg cgcaacatca tccgtgaggt gttccgttcg ctgatggcga
    24541 agcggctgat tgaaatgaaa cgttatcgcg gggcgtttgt ggcaccgcgt aaccagtgga
    24601 attacctcga cactgacgta ctgcaatggg tgctggaaaa tgactacgac ccacggctta
    24661 tcagtgccat gagcgaagtg cgaaatctgg tggaaccggc gattgcccgt tgggcagcag
    24721 agcgcgcgac ttccagcgat ctggcgcaga ttgaatcggc gctgaacgag atgattgcca
    24781 acaatcagga ccgcgaagcg tttaacgaag cggatattcg ctaccacgag gcggtgctgc
    24841 agtcggtgca taacccggtg ttacagcaac ttagcattgc gatcagttcg ctgcagcggg
    24901 cggtttttga acgaacctgg atgggcgatg aggccaacat gccgcaaacg ctccaggaac
    24961 ataaggcgct gttcgatgcg atacgacatc aggacggcga tgcggcagag caggcggcgc
    25021 ttaccatgat cgccagctcg acacgaaggt taaaggaaat cacatgacag ctcgctacat
    25081 cgcaattgac tggggatcga ccaatctgcg cgcctggctt tatcagggcg accactgcct
    25141 ggagagcagg caatcagaag caggcgtcac gcgcctgaac ggaaaatctc cggctgcggt
    25201 gttagcagaa gtcacgaccg actggcgtga agagaaaacg ccagtggtaa tggcaggaat
    25261 ggttggcagc aacgtcggct ggaaagttgc accgtattta tctgttcctg cctgtttttc
    25321 gtctattggc gaacaattaa cgtcagttgg cgacaatatc tggattattc ccggattatg
    25381 tgtctctcat gacgataacc acaatgtgat gcgcggcgaa gaaacacaat tgatcggcgc
    25441 gcgagctctg gctccttcct ctctttatgt catgcccgga acccattgca aatgggtgca
    25501 ggccgatagc cagcaaatca acgattttcg caccgtgatg accggtgaat tacatcattt
    25561 actgttaaat cactcattga ttggcgcagg tttgccgccg caggaaaact ctgccgatgc
    25621 cttcacagct ggccttgagc gtggtcttaa tacgcccgcc atattgccgc agctttttga
    25681 agttcgcgcc tcgcatgtgc tgggaacact tccccgcgaa caggtcagcg aatttctctc
    25741 tggtttgttg attggcgcag aggtcgccag tatgcgcgac tatgtggccc atcaacacgc
    25801 catcaccctt gtcgccggaa catcgctgac cgcgcgctac cagcaagcct ttcaggcgat
    25861 gggttgcgac gtgacggcgg tggcgggcga cacggcattt caggctggta taaggagcat
    25921 cgctcatgca gtggcaaact aaactcccgc tgatcgccat tttgcgcggt attacgcccg
    25981 acgaggcgct ggcgcatgtt ggcgcggtga ttgacgccgg gttcgacgcg gttgaaatcc
    26041 cgctgaattc cccacaatgg gagcaaagca ttcccgccat cgttgatgcg tacggcgaca
    26101 aggcgttgat tggcgcaggt acggtactga aacctgaaca ggtcgatgcg ctcgccagga
    26161 tgggctgtca gctcatcgtt acgcccaata tccatagtga agtgatccgc cgtgcggtgg
    26221 gctacggcat gaccgtctgc cccggctgcg cgacggcgac cgaagccttt accgcgctcg
    26281 aagcgggcgc gcaggcgctg aaaatatttc cgtcatcggc ttttggtccg caatacatca
    26341 aagcgttaaa agcggtattg ccatcggaca tcgcagtctt tgccgttggc ggcgtgacgc
    26401 cagaaaacct ggcgcagtgg atagacgcag gttgtgcagg ggcgggctta ggcagcgatc
    26461 tctatcgcgc cgggcaatcc gtagagcgca ccgcgcagca ggcagcagca tttgttaagg
    26521 cgtatcgaga ggcagtgcaa tgaaaatcac caaaattacc acgtatcgtt tacctccccg
    26581 ctggatgttc ctgaaaattg aaaccgatga aggcgtggtc ggttggggcg agcccgtgat
    26641 cgaaggccgc gcccgtacgg tggaagcggc agttcacgag ctgggtgact atttgattgg
    26701 tcaggatcca tcgcgcatca atgacttatg gcaagtgatg tatcgcgccg gattctatcg
    26761 cggcggtccg atcctgatga gcgccatcgc cgggattgac caggcgttat gggatatcaa
    26821 aggtaaagtg ctgaatgcgc cggtctggca actgatgggc ggcctggttc gcgacaaaat
    26881 taaagcctac agttgggttg gcggcgatcg tccggcggat gttatcgacg gcattaaaac
    26941 gctacgcgaa atcggcttcg ataccttcaa actgaacggt tgtgaagaac tggggctaat
    27001 tgataactcc cgcgcggtag atgcggcggt taacaccgtg gcacaaattc gtgaagcttt
    27061 tggcaatcag attgagtttg gtcttgattt ccacggtcgc gtcagcgcgc cgatggcgaa
    27121 agtgctgatt aaagaactgg agccgtatcg cccgctgttt attgaggagc cggtgctggc
    27181 ggaacaagcc gaatactacc cgaaactggc ggcacaaacg catattccac tggcggcggg
    27241 tgaacgcatg ttctcacgct tcgattttaa acgcgtgctg gaggcaggtg gtatttcgat
    27301 tctgcaaccg gatctctccc acgcgggcgg tattaccgaa tgctacaaaa tcgccggaat
    27361 ggcagaagcc tatgacgtga cccttgcgcc gcactgtccg ctcggaccga ttgcactggc
    27421 ggcttgcctg catatcgact ttgtttccta taacgccgta cttcaggaac aaagtatggg
    27481 aattcattac aacaaaggcg cggagttact cgactttgtg aaaaacaaag aagacttcag
    27541 catggtcggc ggcttcttta aaccgttaac gaaaccgggc ttaggcgtgg aaatcgacga
    27601 agctaaagtg attgagttca gtaaaaatgc cccggactgg cgtaatccgc tctggcgtca
    27661 tgaagataac agcgtagcag agtggtaatt cctgccacgt aagcccctca tcgggcacta
    27721 aaacagcaat acaaaaatat aaccctctgt aaattacagg gcatggtgag cggcttcgct
    27781 atgcccaaaa tctggagaaa gctcgctatg gatattcccg ttaatgcagc aaagccgggg
    27841 cgtcggcgtt atctgacgct ggtgatgatc tttattacgg tagtcatttg ttatgtcgac
    27901 cgcgccaacc tggccgtggc ttccgcccat attcaggaag agttcggcat taccaaagcg
    27961 gaaatgggct atgtattttc ggccttcgcc tggctttata cgctatgtca gatccccggc
    28021 ggttggtttt tagatcgcgt aggttctcgc gtgacttatt ttattgcgat atttggctgg
    28081 tcagtggcga ctttattcca gggctttgcc acgggcttaa tgtcattaat tggtctgcgc
    28141 gcgataaccg gtattttcga agcgcctgct ttcccgacca ataaccggat ggtgaccagc
    28201 tggttcccgg aacatgaacg cgcttctgcc gttggttttt atacgtctgg tcagtttgtc
    28261 ggtctggcgt ttctgacgcc gctgctgatc tggattcagg agatgttgag ctggcactgg
    28321 gtgttcattg tcactggtgg tatcggcatt atctggtcgc tgatttggtt taaggtttat
    28381 cagccgccgc gcctgaccaa aggtatcagc aaagctgaac tggattacat tcgtgatggc
    28441 ggcggtctgg tggatggtga tgcgccggtg aagaaagagg cgcgtcagcc gttaacagcc
    28501 aaagactgga aactggtgtt ccatcgtaaa ctgatcggcg tttatcttgg gcaatttgcg
    28561 gtggcttcta cactgtggtt tttcttaacc tggttcccga actatttaac ccaggaaaaa
    28621 ggaatcacgg cgctgaaagc aggctttatg accacggtgc cattcctcgc ggcgtttgtc
    28681 ggcgtcctgc tctctggctg ggtagcggat ctgctggtac gtaagggctt ttcactgggc
    28741 tttgcgcgta aaacgccgat tatctgcggc ttgctgatct ccacctgcat tatgggcgct
    28801 aactacacta acgatccgat gatgattatg tgcctgatgg cgctggcatt cttcggtaac
    28861 ggttttgctt cgattacctg gtcgctggtt tcttctctgg caccgatgcg cctgattggt
    28921 ttaaccggcg gcgtgtttaa cttcgccggt ggtctgggcg gcatcaccgt tccgctggtg
    28981 gtggggtacc tggcgcaggg ttacggtttc gcacctgcac tggtttatat ctccgccgtc
    29041 gcgttgattg gcgcgctctc ttatatcctg ctggtgggcg atgtgaagcg cgttggctaa
    29101 tccttcaact gtggaatatg tgccacacca ctgcgcataa tccactttct taaagccggt
    29161 gcggtcaggc atcggctttt tactatcttg ccgaagagtt ttaaacgcag tttgcgggtg
    29221 gcgcgccagt aagcggtatt gagcttctct ggctgcttca gtaacaccga acgcagaatg
    29281 tctgtgctat ccagcgcata gctaatcccc tccagcgagc tggcgctgat aaatcccgcc
    29341 gcttcaccaa tcagaaaggc gttgtcctta ccgcagacaa aatcctgcca gcgcgaggga
    29401 aacagcaccg tgcatttttc gcttttcacc gtcttaccaa actggaactg aaaggcgctc
    29461 attttctctt tcagcgtcgt gaaacgcgtc tgaccgtctt tcattggata ggcaccgcca
    29521 aagataaaat aaccgtcttt gctgatactc catgaataac agttagttat cgaattatca
    29581 aagatgcagg agtagaacgg caccggatgt ttctccgcga accactgctg gatagcgaca
    29641 tatttacgga tttgatgatc cgggtagaga tgtcgccgca ccatcgagtt tgcgccatcg
    29701 gcaccgacca gatagcgggc ggtaatatgt tgctcccagc cgtctgcacg aaaaatgaca
    29761 tgccatttat catcctcacg ccagattttt cggcacaggc tgtcgtgata aacctcaacg
    29821 ctggcgggga tcagcgattt catccacaag tcgaaagcat ggcgattaat attgatatag
    29881 cttcgctggt agttacgcgt gagcgatgcg gcgacgtcga cggttttgac gctgaaaatc
    29941 tgcggattag cgatcacatc gacaggaagc gtcagcccat cgcgaataaa agatcgctgc
    30001 gcgtccggtg ccagcagacc gccgcagggt ttgctgaaac cttcagtacc acactggtgc
    30061 tttttatcca gcgcgatcac ctgcattttg cctgctaact ttcgtgccaa cgccgatcct
    30121 gccgggccga ggccaataat cgccacgtcg aaatgttcca tcttttcact cacattcatc
    30181 acgatggcaa aagactattg tctgaaagtg aagtccttgt gaagtatgat ggcgggaccc
    30241 gttttgtatc aggaccgcgc catgaaacag ataacctttg ctccccgtaa tcacctgctc
    30301 accaatacca atacctggac gcccgacagc cagtggctgg tatttgacgt gcgtccttct
    30361 ggcgcgtcgt ttaccggcga gaccattgag cgtgtgaata tccataccgg cgaggtcgag
    30421 gttatctatc gcgcgtcaca gggcgcacac gtcggcgtgg tgaccgttca tccgaagtca
    30481 gagaaatatg ttttcatcca cggcccggaa aatcctgatg aaacatggca ttacgacttc
    30541 catcatcggc gcggagtgat tgttgaaggc ggcaagatga gtaaccttga tgcgatggat
    30601 attaccgcgc cgtatacgcc aggagtgctg cgcggcggca gccatgtgca tgtctttagc
    30661 ccgaacggtg aaagggtgag ctttacctat aacgaccatg taatgcatga actcgatccg
    30721 gcgctggatt tgcgaaacgt cggtgttgct gcgccgtttg gcccggtcaa cgtacaaaag
    30781 cagcatccgc gtgaatacag cggtagccac tggtgcgtgc tggtgagcaa aaccacgccc
    30841 acgccacagc ctggcagtga tgaaatcaat cgtgcttatg aagaaggatg ggtaggaaat
    30901 cacgcgctgg catttattgg cgacacactt tcgccaaagg gcgagaaagt gccggagctg
    30961 tttatcgttg agttaccgca agatgaagct ggctggaaag cggcaggtga tgcgccgtta
    31021 agcggaacgg aaacaaccct gcccgcgcca ccgcgtggcg tcgtgcagcg acgtttaacc
    31081 tttacccacc atcgggctta tccggggtta gtcaacgtcc cgcgccactg ggtgcgctgt
    31141 aatccgcagg gtacacaaat cgcgttttta atgcgagatg ataacggcat tgtgcaactg
    31201 tggcttatct cgccacaggg cggcgagccg cgccagttaa cccataacaa aacggatatt
    31261 cagtctgcat ttaactggca tccgtcagga gaatggttgg gctttgtgct ggataatcga
    31321 attgcttgtg cccatgcgca aagcggcgag gttgagtatt taaccgaaca ccacgccaat
    31381 tcaccttctg cggacgccgt ggtcttctcg ccggatggtc agtggctggc gtggatggaa
    31441 ggcggccagc tgtggatcac cgaaactgat cgctaaatca gttatcaggc attctggccg
    31501 gtggaataac cgcattggtg gcttgcgcgt tggcttcgct tttttcaacg cgcgagcgca
    31561 ccgagctgtc tttgcggaac acatcccacg gcagtaaaag cgtgtccatc acagcggtaa
    31621 acggcatatc gagaatcgcc agcgacttag tgccccagtt ggtttcatcg tcgccaatca
    31681 tggttgcgct ggcgcgggtg ccgggatacg ttccttcttt ccctccggta tgggacatca
    31741 cgctggagca tcctccgagt aatgtcattc cgctgcatat catgaacgct aacaacacat
    31801 ttcttatcat aataaattca tctgttgatc gtgggtgttg gcctgatgag ttatagcgat
    31861 cccttgctga aaataacatc atcattacgt cgcactgtgg cggctatcgc actttaacgt
    31921 ttcgtgctgc cccctcagtc tatgcaatag accataaact gcaaaaaaaa gtccgctgat
    31981 aaggcttgaa aagttcattt ccagacccat ttttacatcg tagccgatga ggacgcgcct
    32041 gatgggtgtt ctggctacct gacctgtcca ttgtggaagg tcttacattc tcgctgattt
    32101 caggagctat tgattatgcg taactttgat ttatccccgc tttaccgttc tgctattgga
    32161 tttgaccgtt tgtttaacca cttagaaaac aaccagagcc agagtaatgg cggctaccct
    32221 ccgtataacg ttgaactggt agacgaaaac cattaccgca ttgctatcgc tgtggctggt
    32281 tttgctgaga gcgaactgga aattaccgcc caggataatc tgctggtggt gaaaggtgct
    32341 cacgccgacg aacaaaaaga gcgcacctat ctgtaccagg gcatcgctga acgcaacttt
    32401 gaacgcaaat tccagttagc tgagaacatt catgttcgtg gtgctaacct ggtaaatggt
    32461 ttgctgtata tcgatctcga acgcgtgatt ccggaagcga aaaaaccgcg ccgtatcgaa
    32521 atcaactaat tccctaaggc cgcctggcgc ggcctgacat ctccatgctc gccgtcaggg
    32581 agcatatgcg aatcttcgga tttgcaggta cttactcgct tcttagaagg agaaatgact
    32641 atgcgtaact tcgatttatc cccactgatg cgtcaatgga tcggttttga caaactggcc
    32701 aacgcactgc aaaacgccgg tgaaagccag agcttcccgc cgtacaacat tgagaaaagc
    32761 gacgataacc actaccgcat tacccttgcg ctggcaggtt tccgtcagga agatttagag
    32821 attcaactgg aaggtacgcg cctgagcgta aaaggcacgc cggagcagcc aaaagaagag
    32881 aaaaaatggc tgcatcaagg gcttatgaat cagccattta gcctgagctt tacgctggct
    32941 gaaaatatgg aagtctctgg cgcaaccttc gtaaacggtt tactgcatat tgatttaatt
    33001 cgtaatgagc ctgaacccat cgcagcgcag cgtatcgcta tcagcgaacg tcccgcgtta
    33061 aatagctaac tagctattct ctttgccccg ccattctggt ggggcttttt ttgtcttact
    33121 tactcaacaa tgcgttaaat ttcgactgtt taagatattt cggcacgttc tttcccgtga
    33181 taatgtgcgc tataaggcaa atctgcttca ccgattcagc cataatccgt agcaattaaa
    33241 atgttatctc aagagaaatg gacgatgagt gatatagcat taacggtcag tattctggct
    33301 ttggtggcag tcgtcggttt gtttatcggc aacgtcaaat ttcgcggcat aggattaggt
    33361 attggcggcg tgctgtttgg tgggatcatc gtcggccatt ttgtttctca ggcggggatg
    33421 acattaagta gcgatatgct gcatgttatt caggaatttg gcctgatcct gttcgtttat
    33481 actatcggga ttcaggtagg gccgggcttc tttgcctcat tgcgcgtctc cggattacgc
    33541 ctcaacctgt ttgctgttct gatcgtcatc atcggtggtc tggttaccgc catcctgcat
    33601 aaactgtttg atattccact gccggtagtg ctggggattt tctccggtgc ggttaccaat
    33661 acgccagcgc tgggggcagg gcagcagatt ttgcgcgacc tgggtacacc aatggaaatg
    33721 gtcgatcaga tggggatgag ttacgcgatg gcgtatccat tcggcatttg cgggattttg
    33781 ttcaccatgt ggatgttgcg ggttattttc cgcgtcaatg tcgagacaga agctcagcag
    33841 cacgagtctt cacgcaccaa tggcggcgcg ctgatcaaga ctatcaatat tcgcgttgag
    33901 aaccctaacc tgcatgattt agccattaaa gatgtaccga ttctcaacgg cgacaaaatt
    33961 atctgctcgc gtctgaaacg cgaagaaacc ctaaaagttc cttcgccaga taccattatc
    34021 caactgggcg atttgctgca tctggtgggt cagccagcgg atttacataa tgcgcaactg
    34081 gtgattggtc aggaggtcga tacttcgctg tccacgaaag gcactgattt gcgcgtcgag
    34141 cgtgtggtgg tcaccaatga aaacgtgctc ggaaaacgta ttcgcgacct gcactttaaa
    34201 gaacgctatg acgttgttat ctcgcgcctg aaccgtgccg gggtcgaact ggtcgccagt
    34261 ggcgatatca gcctgcagtt cggcgatatc ctcaatctgg tggggcgtcc gtccgcaatt
    34321 gatgccgttg ccaatgtgct ggggaatgcg cagcaaaaac tgcaacaggt tcagatgctg
    34381 ccagtgttta ttggcatcgg gctaggcgta ttgttaggtt ctattcccgt ctttgtgcca
    34441 ggattcccgg ccgcgttgaa actggggctg gcgggcggac cgctgattat ggcgttgatc
    34501 ctcgggcgta tcggcagtat cggcaagctg tactggttta tgccgccaag cgccaacctc
    34561 gcgctgcggg agctggggat cgtgctgttc ctctcggtcg ttggtctgaa atctggtggg
    34621 gattttgtga ataccctggt caatggcgaa gggctaagct ggattggtta tggtgccctg
    34681 atcaccgccg ttccgctgat tactgttggc attctggcgc ggatgttagc caaaatgaat
    34741 tacctgacca tgtgcgggat gctggcaggt tccatgaccg atcctccggc gctggcgttt
    34801 gctaataatc ttcatccaac cagcggtgcg gcggcgctct cttacgccac tgtctatccg
    34861 ttggtaatgt tcctgcgcat tatcaccccc caattactgg cggtgctctt ctggagtatc
    34921 ggttaactct tttccgggtg gagtcgccgt aaatggtact ccacctggta ttcgctggca
    34981 tttctgaaca tcactgaata attcaaaaac tccccgctct cgctatatga caacgaggtg
    35041 atccgcagca gtggcgtgtg ttccgctacc ttcatttgcc gcgccagcag tctatcggcg
    35101 agcactggcg tcaggctttc ataattaccg ccaatcaaaa tcccgcactc ttgttcaata
    35161 tattcaaact tcgacccttc cagatgttgc agcgaaagat tacggaacag ttttaccggc
    35221 atatagctgt cttccagcat cagcggtttc ccttccacaa aacgaacgcg acgggagaag
    35281 tagatctgct cgttgatttg aatccgtaac tggctggcaa tggccggagg cgcaggcatg
    35341 atttcaaaaa tcagcacctg gctggtgacc gtttttccct gccgttttaa cacctccacc
    35401 agcccggtca gactggcggt ttgatgcagt acatctttgc gcaccaggta agtgccacta
    35461 ccgtggcggc ggaccaccag cccccacgct accagcaggt caatggcttt acggatggtc
    35521 atccgcgata ccgcaaactc ttccgccagc tttttttcac cgggaagaag gctgtttagc
    35581 gtgaaatctg cggagttaag tcgaattctt aaccgctccg caatgctttt gtagatcatc
    35641 tctagatctc ttttttgcct gcaagcccgg gtaatgcgca cacaagttct gcttaatcga
    35701 ttgaaaaaac atcttttttt aaagatgtgt tcgatgctgt gtacctgtgc tcacagaggt
    35761 ctactttttc gcgaaaacgt agatctctac cgcccaacga aaagcatgaa agcgatcacg
    35821 aatcccattg ggtcgtcatg ttctgccgat cgcatcttcc tatcctcgct ccaggcctgc
    35881 cgcataacca atcaggcttc ctacttacag aattgagaaa agaggatgtg gaaatgctca
    35941 gtcaaattca acgctttggc ggcgcgatgt tcacgccagt gctgctgttt cccttcgccg
    36001 ggattgtggt gggtcttgcc atcttgctgc aaaacccgat gtttgtcggg gaatcactga
    36061 ccgatccgaa cagtttattc gcgcaaatcg tacacattat tgaagagggc ggttggacgg
    36121 tattccgtaa tatgccgctg atttttgctg tcggtttacc cattggcctt gctaagcaag
    36181 cgcaggggcg tgcttgtctg gcggtgatgg tgagtttcct gacctggaac tatttcatca
    36241 acgcgatggg aatgacctgg ggaagctact tcggcgtcga tttcactcag gacgcggtgg
    36301 caggtagcgg tctgacaatg atggccggga ttaaaaccct cgataccagc attatcggcg
    36361 caattatcat ttccggcatt gtgacggcgc tgcataaccg tctgttcgat aaaaaactgc
    36421 cggtttttct cggcattttc caggggacgt cttatgtggt gattatcgcc ttcctggtga
    36481 tgatcccctg tgcctggctg acgttgctcg gctggccaaa agtacaaatg gggattgaat
    36541 ctctgcaagc gttcctgcgt tcggcgggtg cacttggggt ctgggtttac accttcctcg
    36601 aacgtattct gatcccaacc ggtttacacc acttcatcta cggacagttt atctttggtc
    36661 cggcagctgt tgaaggcggc attcagatgt actgggcgca gcatctgcaa gagttcagtt
    36721 tgagcgccga gccgctgaaa tcgttgttcc cggaaggcgg ttttgccctg cacggtaact
    36781 caaaaatctt tggtgccgtg ggcatttctt tagcgatgta cttcactgcc gcaccggaaa
    36841 atcgggtaaa agtggcgggc ttgctgattc ccgcaacctt aaccgccatg ctggtgggaa
    36901 ttaccgaacc gctggaattt accttcctgt tcatttcacc gttgctgttt gcggtacacg
    36961 ccgtgctggc ggcctcaatg tcgaccgtaa tgtatctctt tggtgtggtg ggcaacatgg
    37021 gcggaggtct gattgaccag gttttaccgc aaaactggat cccgatgttc agcaaccacg
    37081 cggatatgat gctgacccaa atcgccattg ggttgtgctt taccctgctg tacttcgtgg
    37141 ttttccgcac actgattctg cagttcaaca tgtgcacgcc gggacgtgaa gatgcggaag
    37201 tgaaactcta ctcaaaagcc gaatacaaag cctcgcgagg ccaaaccacc gcggcagagc
    37261 caaaaaaaga gctggatcag gctgccggta tcctgcaagc cctgggcggg gtcggcaata
    37321 tctccagcat taacaattgc gcgacgcgtt tacgtattgc actgcatgac atgtcacaaa
    37381 cgctggatga cgaagtcttt aaaaagctgg gagcgcacgg cgtcttccgt agtggcgatg
    37441 ccattcaggt gatcattggt ctgcatgtat ctcagctgcg tgaacagctc gatagcttaa
    37501 ttaattctca tcaatcagca gaaaatgttg ccattacgga ggcagtatag tgaccaaatt
    37561 ctcagtggtt gtcgcaggcg gtggaagcac ctttacgcca ggcatcgtgt tgatgctcct
    37621 ggcgaatcag gaccgtttcc cgcttcgtgc actgaaattt tatgataacg atggtgcgcg
    37681 gcaggaagtg attgccgaag cctgtaaagt catccttaaa gaaaaagcgc cggacattgc
    37741 gtttagttac accaccgatc ctgaagtggc attcagcgac gttgattttg tcatggcgca
    37801 catccgcgtc ggcaaatacc cgatgcgcga actggatgaa aaaatcccgc tgcgccacgg
    37861 cgttgttggt caggaaactt gcggacccgg cggaatagcg tacggcatgc gttccattgg
    37921 cggcgtcctg gaactggtgg attatatgga aaaatattca ccaaatgcct ggatgctcaa
    37981 ctactccaac ccggcagcca ttgtcgcaga agccacgcgt cgtctgcgcc cgaatgcgaa
    38041 aatcctcaac atctgtgaca tgccaatcgg tattgaaagc cggatggcgc aaattgttgg
    38101 gctgcaagat cgcaaacaga tgcgcgtgcg ctactacggc ctgaaccact ggtggtcggc
    38161 gatatcccgc agtttcagaa agggttaatg agtcagcaag tggcggtgga aaaactggtc
    38221 gtggacgcct gggaacagcg ttcatatcag cacctgtggc aggcgattac gttgtcgaaa
    38281 acggtaccga gcgcctcggt cgccaaagct attctggatg agttgctgga ggccaacaaa
    38341 gcgtactggc cagagttacg ttaattgtgt ggactggcat ccgttgggtg ctggtccgta
    38401 ttctttagca cggctgacgg cgcataacca aatttatgtt taaaggcttt gctgaaatga
    38461 aaggagtcga agaagttgag cgtatcagcg acttcgccaa ccgagtttcc ttgttgcttt
    38521 aatagcgata gcgccagatc cagacgcgca tcgaggtaat attctttcgg cgtcttgccg
    38581 gtatagcgta aaaacagacg acgcaaccag gcttcgctac aggggatcgt ggcagccata
    38641 tcagctacgc tccagcgttg ttgcagactg gcatgtaaag tggcaattaa tttttcaatt
    38701 tgccgccgtt gtggatcttt tttaccatct gcgtacataa gacaaatcca ctgataaata
    38761 attttcgtca gaaaagcgac tgccagatta ttttttattg cttctggtga agttattaac
    38821 tcagcaactt cggtgagttc ctgattataa atttcgccat tataaataac gctttgctga
    38881 ccaacgggaa tatccatcat gctggtgggg gtaaattcca tccagtactg ttcccagact
    38941 aaaccttcac agtgataaga gtgaatatcc attggcttta agaatataat acagttgcca
    39001 tgcagtgtta tttgttcgcc attctttaaa agaattttcc cacatccttg tacggtatac
    39061 accgcaaccc atgagttggc gataagcggt ttcttcttgt cccgcggcca gatcacccgg
    39121 taatgctcgt cggcgtaggt atgccagagc gagatcagag aaattccgct ggagatcaca
    39181 ttttcgttaa tcaataaggg aatattgtac ggagtttcgt tttttacatc tgaactttgc
    39241 aattttccat tcattttaat atccctccgg cgaattatgc tcacaacctg aacttaacag
    39301 aaaacaatcc gttcagggat acgacgtttg tattttaaga atctgactgc ctgacccgac
    39361 gcattttacc tctccctata ttcatgcgtc cgggacataa acataaataa gggctatgag
    39421 atgaattcgt tacaaatctt gagttttgtc ggttttacgc tgctggtggc ggtgatcacc
    39481 tggtggaagg tccgcaaaac agataccgga tcgcaacaag gctattttct tgccggacgt
    39541 tcactaaaag cgccggttat tgccgcttcg ttaatgctaa ccaacctttc cacggaacaa
    39601 ctggtcggcc tttccgggca ggcctacaaa agcggcatgt cggtgatggg ctgggaagtg
    39661 acttcagcgg tgacgctgat cttcctcgcg ctaatctttt taccgcgcta tctgaagcgc
    39721 ggcattgcca ccatccccga ttttctggag gaacgttatg ataaaacgac gcgtattatc
    39781 atcgacttct gcttcctaat tgccaccggc gtctgctttc tgccgattgt tctctactcc
    39841 ggcgcgttgg cgctcaacag cctgtttcac gtcggggaat cgctacagat ttctcacggt
    39901 gcggctatct ggctactggt aattttgctt ggtctggcgg gaattttgta tgcggtgatc
    39961 ggcggactgc gcgcaatggc agtggcggac tccatcaacg gtattgggct ggttatcggc
    40021 gggttgatgg tgccggtatt tggcctgatc gcgatgggca agggcagctt tatgcagggc
    40081 attgagcaac tcaccaccgt tcacgccgag aaattaaact caatcggtgg cccgaccgat
    40141 cccttgccga ttggcgcggc atttaccggt ttgattctgg tgaacacctt ttactggtgt
    40201 acaaatcagg gcatcgtgca acgcacgctg gcgtcaaaaa gcctggcgga agggcaaaag
    40261 ggggcgctgt taacggcggt gctgaaaatg ctcgacccgc tggtactggt gctgccaggg
    40321 ttgattgcgt ttcatctgta tcaggattta ccgaaagccg acatggccta cccgacgctg
    40381 gtcaataacg ttctgccagt gccaatggtg ggtttcttcg gcgcggtgtt atttggtgcg
    40441 gtgatcagta ccttcaacgg ctttctgaat agcgccagta cgttattcag tatgggtatt
    40501 taccgtcgca tcattaacca gaatgccgag ccgcagcagc tggtcaccgt cgggcgcaaa
    40561 tttggtttct ttatcgctat cgtttcggtg ctggtcgcgc cgtggatcgc caacgcgccg
    40621 caggggctgt atagctggat gaaacagctc aacggcattt acaacgtgcc gctggttacc
    40681 atcatcatta tgggcttttt cttcccgcgc atcccggcgc tggcggcaaa agtagcgatg
    40741 gggattggca taatcagcta catcaccatc aactatctgg tgaagttcga cttccatttc
    40801 ctctatgtgc tggcctgtac gttctgcatc aacgtggtcg tgatgctggt gatcggtttt
    40861 atcaaaccgc gcgccacgcc gttcaccttc aaagatgcgt ttgcggtgga catgaaaccg
    40921 tggaaaaacg tcaagatcgc gtcaattggc atcctgttcg cgatgattgg cgtctatgcc
    40981 gggctggctg aattcggcgg ctacggtacg cgctggttag cgatgatcag ttatttcatt
    41041 gccgccgtag tgattgtcta cctgattttt gacagctggc ggcatcgtca cgacccagcc
    41101 gtaaccttta ctcccgacgg gaaggatagc ctatgaaacg ccccaatttt ctgttcgtca
    41161 tgaccgatac ccaggccacc aatatggtcg gttgctatag cggtaaaccg ctgaatacgc
    41221 aaaatattga tagtctggcg gcggaaggta ttcgctttaa ttccgcctac acctgttcac
    41281 cggtttgtac gcctgcacgg gccggactat ttaccggtat ctacgctaac cagtccggcc
    41341 cgtggaccaa caacgtcgcg ccaggcaaaa acatctccac tatggggcgc tactttaagg
    41401 atgccggcta tcacacctgt tacatcggca aatggcatct cgacggtcat gactatttcg
    41461 gcactggcga gtgtccgccg gagtgggacg ctgattactg gttcgatggg gcgaactatc
    41521 ttagcgaact gacggaaaaa gagattagcc tgtggcgcaa tggcctaaac agcgtcgaag
    41581 atttacaggc gaaccatatc gacgaaacct tcacctgggc gcatcgtatc agcaatcggg
    41641 cggtggattt tctgcaacag cctgcgcgcg cagacgagcc tttcctgatg gtggtttcgt
    41701 atgatgagcc gcatcacccg ttcacctgtc cggtggagta tttagagaaa tacgctgatt
    41761 tttactacga gctgggcgag aaagcacagg atgacctggc taacaaaccg gaacatcacc
    41821 gcttatgggc gcaggcgatg ccatcgccag tcggtgatga cgggctttat caccatccgc
    41881 tctattttgc ctgtaatgac tttgttgatg accaaatcgg acgggtcatc aatgccttaa
    41941 cgccagagca acgtgaaaat acgtgggtta tttatacctc cgatcacggc gaaatgatgg
    42001 gcgcacataa gctgatcagt aaaggggcgg cgatgtatga cgacatcacc cgcattccgc
    42061 tgatcatccg ttcgccgcaa ggggagcggc gacaggtcga tacgccagtc agtcatatcg
    42121 atttactgcc gacaatgatg gcgctggcag atattgaaaa accagagatt ctgccggggg
    42181 aaaatatcct tgccgtgaaa gagccacgcg gcgtgatggt ggaatttaac cgctacgaga
    42241 ttgagcatga cagctttggc ggttttattc cggtgcgttg ctgggtgacg gatgacttta
    42301 aactggtact caacctcttc accagtgatg aactttacga tcgccgtaat gacccaaatg
    42361 aaatgcataa cctgatcgat gatatccgtt ttgcagacgt tcgcagcaaa atgcatgacg
    42421 ccttattgga ttacatggac aaaattcgcg atccgttccg cagttaccaa tggagtctgc
    42481 gtccgtggcg taaagatgca cggccgcgct ggatgggggc gtttcgtcca cgtccacaag
    42541 atggctattc gccagttgta cgcgactatg acaccggcct accgacacaa ggggtgaagg
    42601 tggaggagaa aaaacagaag ttctgacgat aatgcccgct gatgatcacc cggcgggcat
    42661 tattcaggct gcttaaacca gtgaaccgcc ggtcaggaag gaaaagataa ggaatatcag
    42721 caaaatgctg cacacgatgc cgataccaaa aagcaaggta tggaaagcca gcgtcccgcc
    42781 gccaaaaacc agcgcgccgc gaatgcccca gcgattttcc ttacgcatac cgccaataaa
    42841 tgcgcaaagt agcgcagcaa tggccagtgc gataccgctt tgattgagga ttttatcgac
    42901 atctacgtcc tcttttttct ccacggtggt aattttttcg ccttttattc cggcgagaag
    42961 acctctttta atttcagccg ttttgtccgc cacgatgctt tcaaacgttg gcggtggtgc
    43021 ggagaaaggg ccgaatgaaa agtggataat ccccatcatt aaagcgatgg caccgaacag
    43081 catgcccaat gaactgattt tattttgagc tatgataccc atctgacctc cttgtagcgg
    43141 atggcaaaag catatcagga aacgggcgga cgaaattctt aaaaaaaccg ctaaaggtag
    43201 agcgttagtg aaattgcaaa ggagcaacaa tgaaaatttc ccgcctcgga gaagcgcctg
    43261 attaccgctt ctcgctggct aatgagcgta cttttctggc gtggatccgt actgcactag
    43321 gatttctggc ggcgggggtt gggcttgatc aacttgcgcc agatttcgcc acgcccgtca
    43381 ttcgcgaact gctggcgttg ttgttgtgtc tgttttccgg cgggttagcg atgtatggct
    43441 acttgcgctg gttacgcaat gaaaaagcga tgcgtctgaa agaggacctg ccctacacca
    43501 acagcttatt aatcattagc ttaatattga tggtcgtggc ggtgatcgtt atgggactgg
    43561 tgttgtatgc cggatagccg caaagccaga cgcattgccg acccaggact gcagccggag
    43621 cgcacatcac tggcgtggtt tcgtaccatg ctgggctacg gcgcgttgat ggcgttggct
    43681 atcaaacaca actggcacca ggcgggcatg ttattctgga tttcgattgg cattctcgcc
    43741 atcgtggcgc tgatcctctg gcactacacc cgtaatcgca atttaatgga tgtcacgaat
    43801 agcgattttt cccaatttca cgtagtccgt gacaaatttt tgatctccct cgcggtgtta
    43861 tctctcgcaa tactgtttgc tgtaacgcat atacatcaac ttatcgtatt tattgagaga
    43921 gtcgcatgac aggaagtcag gtcattgatg ctgaagagga caggcataaa ctggttgtag
    43981 agtacaagga tgctctgcaa cctgccgatt tttatcacaa tttcaaacag cggggcatcc
    44041 gctccgtaca gctcattccc tatcttgaat ttgatgaccg gggcgatctg acggccgctt
    44101 cggtgacagc agagctgtgg gggaaatttt taattgccct gttcgagtgt tgggtgcggg
    44161 cagatatcag tcgtatctcg attgagcttt ttgacgccac cttacaaaaa tggtgtggca
    44221 gcgaaaaccc gcaaccgcgc tgtgactgcc aggcgtgcga ctggcatcgc ctgtgcccgc
    44281 acgctcggca ggagacgcca gacagcgtgc tttgtgcggg ctatcaggcg ttttattctt
    44341 actccgcacc gcatatgcgg gtgatgcgtg atctgataaa gcagcatcgt tctcccatgg
    44401 agctgatgac gatgctgcgg tgacgtgcgc ttaaacgggc tgcccctgat gcgacatccg
    44461 cgtcgccagc ggcagccagc acagcacgat caacaatccc attaaggtca tcaacaaccc
    44521 caggctgccc tgaccggttt gcggcaacat cgcagagagc gacgccagca cgccggaacc
    44581 aatgttttgc agaccgccga ccagcgcgcc agccgtgccc gccaggaagg ggaacggctc
    44641 catcgcgccg ctggtcgcca gcggaa
//
LOCUS       DACAOP010000029        43327 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.029, whole genome shotgun sequence.
ACCESSION   DACAOP010000029 DACAOP010000000
VERSION     DACAOP010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43327
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.029"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            3..275
                     /locus_tag="IT892_001788"
     CDS             3..275
                     /locus_tag="IT892_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001306068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP3135012.1"
                     /translation="MRPYVERGTVKEFGLWDVVQQGKISVYVADALLKKGSMKTGDKL
                     DIKGVGQVEVSPNSVQGYDYEADGNGIVLLPERVIFNKENIGKYDF"
     gene            302..1177
                     /gene="lsrF"
                     /locus_tag="IT892_001789"
     CDS             302..1177
                     /gene="lsrF"
                     /locus_tag="IT892_001789"
                     /EC_number="2.3.1.245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /protein_id="HAP3135013.1"
                     /translation="MADLDDIKDGKDFRTDQPQKNIPFTLKGCGALDWGMQSRLSRIF
                     NPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFEHADVLMCTRGILRSVVPPATNR
                     PVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLV
                     DAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGAQIIKTYYVEKGFERIVAGC
                     PVPIVIAGGKKLPEREALEMCWQAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHN
                     ETADRAYELYLSEKQ"
     gene            1201..1491
                     /gene="lsrG"
                     /locus_tag="IT892_001790"
     CDS             1201..1491
                     /gene="lsrG"
                     /locus_tag="IT892_001790"
                     /EC_number="5.3.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione
                     isomerase"
                     /protein_id="HAP3135014.1"
                     /translation="MHVTLVEINVHEDKVDEFIEVFRQNHLGSVQEEGNLRFDVLQDP
                     EVNSRFYIYEAYKDEDAVAFHKTTPHYKTCVAKLESLMTGPRKKRLFNGLMP"
     gene            1548..2306
                     /gene="tam"
                     /locus_tag="IT892_001791"
     CDS             1548..2306
                     /gene="tam"
                     /locus_tag="IT892_001791"
                     /EC_number="2.1.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="HAP3135015.1"
                     /translation="MSDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGN
                     STALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANAS
                     LQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLA
                     GVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFL
                     KRYHQMLEEQYPLQENGQILLAFPRLFIVARRME"
     gene            complement(2310..3224)
                     /locus_tag="IT892_001792"
     CDS             complement(2310..3224)
                     /locus_tag="IT892_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bestrophin family inner membrane protein"
                     /protein_id="HAP3135016.1"
                     /translation="MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPW
                     YTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKT
                     TLPDSASVREFARLQIAFAHCLRMTLRKQPQAEVLAHYLKTEDLQRVLASNSPANRIL
                     LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTV
                     YLFCIMLPFALVVDLHYMTPFISVLISYTFISLDCLAEELEDPFGTENNDLPLDAICN
                     AIEIDLLQMNDEAEIPAKILPDRHYQLT"
     gene            complement(3431..4882)
                     /locus_tag="IT892_001793"
     CDS             complement(3431..4882)
                     /locus_tag="IT892_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAP3135017.1"
                     /translation="MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDL
                     NSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEY
                     DEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGA
                     LDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTG
                     YPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKP
                     YKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRD
                     ELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFA
                     LAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWE
                     QDLTQVPGLVEQVANDLDAILEKGMREAVRPLC"
     gene            complement(5109..6056)
                     /locus_tag="IT892_001794"
     CDS             complement(5109..6056)
                     /locus_tag="IT892_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HAP3135018.1"
                     /translation="MLADWFSEQFSTGVLIVPCMLTLAIPGVLPRFKAEQMMPAIALI
                     VSVIASVVIGGAGSLAFPLPALIWCAVRYTPQVTCLLTFVTGAVEIVLVANSVIDISV
                     GSPFSIPQMFSARLGIATMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYSRSGL
                     YEALKSPSLKQTQHLTVMLLDIDYFKSINDNYGHECGDKVLSVFARHIQKIVGDKGLV
                     ARMGGEEFAVAVPSVNPVDGLLMAEKIRKGVELQPFTWQQKTLYLTVSIGVGSGRASY
                     LTLTDDFNKLMVEADTCLYRSKKDGRNRTSTMRYGEEVV"
     gene            complement(6168..6527)
                     /locus_tag="IT892_001795"
     CDS             complement(6168..6527)
                     /locus_tag="IT892_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4186 domain-containing protein"
                     /protein_id="HAP3135019.1"
                     /translation="MQSLDPLFARLSRSKFRSRFRLGMKERQYCLEKGAPVIEQHAAD
                     FVAKRLAPALPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHNIPQGVSLSEEQQR
                     YIVAVIYHWLVVQMNQP"
     gene            complement(6527..7453)
                     /gene="glsB"
                     /locus_tag="IT892_001796"
     CDS             complement(6527..7453)
                     /gene="glsB"
                     /locus_tag="IT892_001796"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase B"
                     /protein_id="HAP3135020.1"
                     /translation="MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIA
                     ICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLV
                     QLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
                     EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKA
                     IHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAI
                     AVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY"
     gene            complement(7517..8905)
                     /gene="sad"
                     /locus_tag="IT892_001797"
     CDS             complement(7517..8905)
                     /gene="sad"
                     /locus_tag="IT892_001797"
                     /EC_number="1.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="HAP3135021.1"
                     /translation="MTITPATHAISINPATGEQLSVLPWAGADDIENALQLAAAGFRD
                     WRETNIDYRAEKLRDIGKALRARSEEMAQMITREMGKPINQARAEVAKSANLCDWYAE
                     HGPAMLKAEPTLVENQQAVIEYRPLGTILAIMPWNFPLWQVMRGAVPIILAGNGYLLK
                     HAPNVMGCAQLIAQVFKDAGIPQGVYGWLNADNDGVSQMIKDSRIAAVTVTGSVRAGA
                     AIGAQAGAALKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFII
                     EEGIASAFTERFVAAAAALKMGDPRDEENALGPMARFDLRDELHHQVEKTLAQGARLL
                     LGGEKMAGAGNYYPPTVLANVTPEMTAFREEMFGPVAAITIAKDAEHALELANDSEFG
                     LSATIFTTDETQARQMAARLECGGVFINGYCASDARVAFGGVKKSGFGRELSHFGLHE
                     FCNIQTVWKDRI"
     gene            9006..9887
                     /locus_tag="IT892_001798"
     CDS             9006..9887
                     /locus_tag="IT892_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3135022.1"
                     /translation="MDLTQLEMFNAVAEAGSITQAAAKVHRVPSNLTTRLRQLETELG
                     VDLFIRENQRLRLSPAGHNFLRYSQQILALVDEARSVVAGDEPQGLFSLGSLESTAAV
                     RIPATLAEFNRRYPKIQFSLSTGPSGTMLDGVLEGKLNAAFIDGPINHTAIDGIPVYR
                     EELMIVTPQGYAPVTRASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESY
                     HGMLACVIAGAGIALIPRSMLESMPGHHQVEAWPLAEQWRWLTTWLVWRRGAKTRPLE
                     AFIQLLDVPDSARQGYQ"
     gene            9965..11080
                     /gene="yneK"
                     /locus_tag="IT892_001799"
     CDS             9965..11080
                     /gene="yneK"
                     /locus_tag="IT892_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein YneK"
                     /protein_id="HAP3135023.1"
                     /translation="MVTPVSISNYISLPDDFPVRNIAPQVKEVLKDFIDALSTIICNE
                     EWRTSLNINSATKKIFNNLDNLSYIQRTSFRGNDTLYNEKVQFKLIYPARNGRHKENI
                     EFQVVINLSPIYLDNFRHDGEINIFCAPNPKPVTMGRVFQTGVERVLFLFLNDFIEQF
                     PMINPGVPIKRAHTPHIEPLPSDHHTAADYLRQFDLLVLNFISRGNFVILPRLWNNSE
                     VHRWFVNKDPNLITAILDITDSELKEDLLQSLMDSLGSNKHVLPEVCICFLSLLAEQE
                     SPHFQNLFLFFANMLLHYHQFMNPNESDLNDVLMPASLSDDKIIKHMARRTLKLFVKN
                     ETPPKVTHEDLVKNRPRSPVRPPIPATAKTPDLPERH"
     gene            11230..12420
                     /gene="ydeA"
                     /locus_tag="IT892_001800"
     CDS             11230..12420
                     /gene="ydeA"
                     /locus_tag="IT892_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose MFS transporter"
                     /protein_id="HAP3135024.1"
                     /translation="MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFH
                     MQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFT
                     VLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIV
                     GQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLT
                     VVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASAL
                     VSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVA
                     MALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLE
                     EQTQ"
     gene            complement(12445..13110)
                     /gene="marC"
                     /locus_tag="IT892_001801"
     CDS             complement(12445..13110)
                     /gene="marC"
                     /locus_tag="IT892_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter MarC"
                     /protein_id="HAP3135025.1"
                     /translation="MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQS
                     LMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSP
                     EAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
                     PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIK
                     TYH"
     gene            13322..13756
                     /gene="marR"
                     /locus_tag="IT892_001802"
     CDS             13322..13756
                     /gene="marR"
                     /locus_tag="IT892_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416047.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance transcriptional
                     regulator MarR"
                     /protein_id="HAP3135026.1"
                     /translation="MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFK
                     VLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTT
                     GGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP"
     gene            13776..14159
                     /gene="marA"
                     /locus_tag="IT892_001803"
     CDS             13776..14159
                     /gene="marA"
                     /locus_tag="IT892_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707445.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     MarA"
                     /protein_id="HAP3135027.1"
                     /translation="MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQR
                     MFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDV
                     PPHKYRMTNMQGESRFLHPLNHYNS"
     gene            14191..14409
                     /gene="marB"
                     /locus_tag="IT892_001804"
     CDS             14191..14409
                     /gene="marB"
                     /locus_tag="IT892_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance protein MarB"
                     /protein_id="HAP3135028.1"
                     /translation="MKPLSSAIAAALILFSAQGVAEQTTQPVVTSCANVVVVPPSQEH
                     PPFDLNHMGTGSDKSDALGVPYYNQHAM"
     gene            complement(14520..15338)
                     /gene="eamA"
                     /locus_tag="IT892_001805"
     CDS             complement(14520..15338)
                     /gene="eamA"
                     /locus_tag="IT892_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001375197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylserine/cysteine exporter"
                     /protein_id="HAP3135029.1"
                     /translation="MSRKDGVLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVA
                     FPAIFFVARPKVPLNLLLGYGLTISFAQFAFLFCAINFGMPAGLASLVLQAQAFFTIM
                     LGAFTFGERLHGKQLAGIALAIFGVLVLIEDSLNGQHVAMLGFMLTLAAAFSWACGNI
                     FNKKIMSHSTRPAVMSLVIWSALIPIIPFFVASLILDGSATMIHSLVTIDMTTILSLM
                     YLAFVATIVGYGIWGTLLGRYETWRAAPLSLLVPVVGLASAALLLDERLTGLQF"
     gene            15533..16720
                     /gene="ydeE"
                     /locus_tag="IT892_001806"
     CDS             15533..16720
                     /gene="ydeE"
                     /locus_tag="IT892_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux MFS transporter YdeE"
                     /protein_id="HAP3135030.1"
                     /translation="MNLSLRRSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDL
                     IGYAMTIALTIGVVFSLGFGILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLF
                     FALINCAYSVFATVLKAWFADNLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI
                     NLPFWLAAICSAFPMLFIQIWVKRSEKIIATETGSVWSPKVLLQDKALLWFTCSGFLA
                     SFVSGAFASCISQYVMVIADGDFAEKVVAVVLPVNAAMVVTLQYSVGRRLNPANIRAL
                     MTAGTLCFVIGLVGFIFSGNSLLLWGMSAAVFTVGEIIYAPGEYMLIDHIAPPEMKAS
                     YFSAQSLGWLGAAINPLVSGVVLTSLPPSSLFVILALVIIAAWVLMLKGIRARPWGQP
                     ALC"
     gene            16847..16942
                     /gene="mgtS"
                     /locus_tag="IT892_001807"
     CDS             16847..16942
                     /gene="mgtS"
                     /locus_tag="IT892_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtS"
                     /protein_id="HAP3135031.1"
                     /translation="MLGNMNVFMAVLGIILFSGFLAAYFSHKWDD"
     gene            complement(17161..18051)
                     /gene="dgcZ"
                     /locus_tag="IT892_001808"
     CDS             complement(17161..18051)
                     /gene="dgcZ"
                     /locus_tag="IT892_001808"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcZ"
                     /protein_id="HAP3135032.1"
                     /translation="MIKKTTEIDAILLNLNKAIDAHYQWLVSMFHSVVARDASKPEIT
                     DNHSYGLCQFGRWIDHLGPLDNDELPYVRLMDSAHQHMHNCGRELMLAIVENHWQDAH
                     FDAFQEGLLSFTAALTDYKIYLLTIRSNMDVLTGLPGRRVLDESFDHQLRNAEPLNLY
                     LMLLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKAAN
                     DEEACRAGVRICQLVDNHAITHSEGHINITVTAGVSRAFPEEPLDVVIGRADRAMYEG
                     KQTGRNRCMFIDEQNVINRV"
     gene            complement(18306..18698)
                     /gene="ydeI"
                     /locus_tag="IT892_001809"
     CDS             complement(18306..18698)
                     /gene="ydeI"
                     /locus_tag="IT892_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdeI family stress tolerance OB fold protein"
                     /protein_id="HAP3135033.1"
                     /translation="MKFQAIVLASFLVMPYALADDQGGLKQDAAPPPPHAIEDGYRGT
                     DDAKKMTVDFAKTMHDGASVSLRGNLISHKGEDRYVFRDKSGEINVVIPAAVFDGREV
                     QPDQMINISGSLDKKSAPAVVRVTHLQK"
     gene            18974..19492
                     /locus_tag="IT892_001810"
     CDS             18974..19492
                     /locus_tag="IT892_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-tetronate isomerase"
                     /protein_id="HAP3135034.1"
                     /translation="MNINRDKIVQLVDTDTIENLTSALSQRLIADQLRLTTAESCTGG
                     KLASALCAAEDTPKFYGAGFVTFTDQAKMKILSVSQQSLERYSAVSEKVAAEMATGAI
                     ERADADVSIAITGYGGPEGGEDGTPAGTVWFAWHIKGQNYTAVMHFAGDCETVLALAV
                     RFALAQLLQLLL"
     gene            complement(19536..21581)
                     /gene="dcp"
                     /locus_tag="IT892_001811"
     CDS             complement(19536..21581)
                     /gene="dcp"
                     /locus_tag="IT892_001811"
                     /EC_number="3.4.15.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-dipeptidase Dcp"
                     /protein_id="HAP3135035.1"
                     /translation="MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIA
                     AIALNPQMPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAEL
                     ANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKV
                     LNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWL
                     IPLLNTTQQPALAEMRDRATREKLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQATLL
                     GFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQGGFSAQP
                     WDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYH
                     PDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNKTHPVIYNVCNYQ
                     KPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHW
                     ATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLEE
                     NEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADD
                     GYQWFVEQGGLTRENGLRFREAILSRGNSEDLERLYRQWRGKAPKIMPMLQHRGLNI"
     gene            21718..22464
                     /gene="ydfG"
                     /locus_tag="IT892_001812"
     CDS             21718..22464
                     /gene="ydfG"
                     /locus_tag="IT892_001812"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /protein_id="HAP3135036.1"
                     /translation="MIVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDEL
                     GDNLYIAQLDVRNRAAIEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETM
                     IDTNNKGLVYMTRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
                     LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWW
                     VSTLPAHVNINTLEMMPVTQSYAGLNVHRQ"
     gene            22553..23239
                     /locus_tag="IT892_001813"
     CDS             22553..23239
                     /locus_tag="IT892_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP3135037.1"
                     /translation="MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVR
                     FNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISMAQVRNGSFIRQAIECAVARRAA
                     SMITESQCYQLEQNLHQQRIAIERKQLDDFFELDDNFHQLLTQIADCQLAWDTIENLK
                     ATVDRVRYMSFDHVSPPEMLLRQHLDIFSALQKRDGDAVERAMTQHLQEISESVRQIR
                     QENSDWFSEE"
     gene            23416..23619
                     /gene="ydfZ"
                     /locus_tag="IT892_001814"
     CDS             23416..23619
                     /gene="ydfZ"
                     /locus_tag="IT892_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium delivery protein YdfZ"
                     /protein_id="HAP3135038.1"
                     /translation="MTTYDRNRNAITTGSRVMVSGTGHTGKILSIDTEGLTAEQIRRG
                     KTVVVEGCEEKLAPLDLIRLGMN"
     gene            complement(23654..25114)
                     /locus_tag="IT892_001815"
     CDS             complement(23654..25114)
                     /locus_tag="IT892_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAP3135039.1"
                     /translation="MGNNLLSAKATLPVYDRNNLAPRIVHLGFGAFHRAHQGVYADIL
                     ATEHFSDWGYYEVNLIGGEQQIADLQQQDNLYTVAEMSADVWTARVVGVVKKALHVQI
                     DGLETVLAAMCEPQIAIVSLTITEKGYFHSPATGQLMLDHPMVAADVQNPHQPKTATG
                     VIVEALARRKAAGLPAFTVMSCDNMPENGHVMRDVVTSYAQAVDVKLAQWIEDNVTFP
                     STMVDRIVPAVTEDTLAKIEQLTGVRDPAGVACEPFRQWVIEDNFVAGRPEWEKAGAE
                     LVSDVLPYEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDEHYRYAAYGLMLQEQAP
                     TLKVQGVDLQDYANRLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLAHDSKF
                     DLLALGVARWMRYVGGVDEQGNPIEISDPLLPVIQKAVQSSAEGKARVQSLLAIKAIF
                     GDDLPDNSLFTARVTETYLSLLAHGAKATVAKYSVK"
     gene            complement(25203..26570)
                     /locus_tag="IT892_001816"
     CDS             complement(25203..26570)
                     /locus_tag="IT892_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HAP3135040.1"
                     /translation="MTIEKHERSTKDLVKAAVSGWLGTALEFMDFQLYSLGAALVFHE
                     IFFPESSTAMALILAMGTYGAGYVARIVGAFIFGKMGDRIGRKKVLFITITMMGICTT
                     LIGVLPTYAQIGVFAPILLVTLRIIQGLGAGAEISGAGTMLAEYAPKGKRGIISSFVA
                     MGTNCGTLSATAIWAFMFFILSKEELLAWGWRIPFLASVVVMVFAIWLRMNLKESPVF
                     EKVNDSNQPTAKPAPAGSMFQSKSFWLATGLRFGQAGNSGLIQTFLAGYLVQTLLFNK
                     AIPTDALMISSILGFMTIPFLGWLSDKIGRRIPYIIMNTSAIVLAWPMLSIIVDKSYA
                     PSTIMVALIVIHNCAVLGLFALENITMAEMFGCKNRFTRMAISKEIGGLIASGFGPIL
                     AGIFCTMTESWYPIAIMIMAYSVIGLISALKMPEVKDRDLSALEDAAEDQPRVVRAAQ
                     PSRSL"
     gene            complement(26628..27647)
                     /locus_tag="IT892_001817"
     CDS             complement(26628..27647)
                     /locus_tag="IT892_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent oxidoreductase"
                     /protein_id="HAP3135041.1"
                     /translation="MKSILIEKPNQLAIVEREIPTPSAGEVRVKVKLAGICGSDSHIY
                     RGHNPFAKYPRVIGHEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNV
                     CTTLAVLGVHADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTE
                     NDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPL
                     GEIFTEKGIKPTLIIDAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKE
                     LSIFSSRLNANKFPIVIDWLSKGLIKPEKLITHTFDFQHVADAISLFEQDQKHCCKVL
                     LTFSE"
     gene            complement(27659..28873)
                     /gene="rspA"
                     /locus_tag="IT892_001818"
     CDS             complement(27659..28873)
                     /gene="rspA"
                     /locus_tag="IT892_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="starvation-sensing protein RspA"
                     /protein_id="HAP3135042.1"
                     /translation="MKIVKAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVA
                     SYLQDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGHSIDEALDDYARHQELGFKAIRVQCGIPGMKTTYG
                     MSKGKGLAYEPATKGQWPEEQLWSTEKYLDFMPKLFDAVRNKFGFNEHLLHDMHHRLT
                     PIEAARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTLTHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWV
                     PNFGVQEYMGYSEQMLEVFPHNWTFDNGYMHPGDKPGLGIEFDEKLAAKYPYEPAYLP
                     VARLEDGTLWNW"
     gene            complement(29079..29405)
                     /locus_tag="IT892_001819"
     CDS             complement(29079..29405)
                     /locus_tag="IT892_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HAP3135043.1"
                     /translation="MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLAL
                     FVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIV
                     AGWGRT"
     gene            29540..29881
                     /locus_tag="IT892_001820"
     CDS             29540..29881
                     /locus_tag="IT892_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1283 family protein"
                     /protein_id="HAP3135044.1"
                     /translation="MKITLSKRIGLLAILLPCALALSTTVHAETNKLVIESGDSAQSR
                     QHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRC
                     LDRRTGRVITP"
     gene            29916..30476
                     /gene="speG"
                     /locus_tag="IT892_001821"
     CDS             29916..30476
                     /gene="speG"
                     /locus_tag="IT892_001821"
                     /EC_number="2.3.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine N1-acetyltransferase"
                     /protein_id="HAP3135045.1"
                     /translation="MPSAHSVKLRPLEREDLRYVHQLDNNASVMRYWFEEPYEAFVEL
                     SDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQIIISPEYQGKGLATR
                     AAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFSVEGELMHEFFINGQYRNAI
                     RMCIFQHQYLAEHKTPGQTLLKPTAQ"
     gene            complement(30479..31189)
                     /locus_tag="IT892_001822"
     CDS             complement(30479..31189)
                     /locus_tag="IT892_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfC family lipoprotein"
                     /protein_id="HAP3135046.1"
                     /translation="MKYKLLPCLLAIFLTGCDRTEVTLSFTPEMASFSNEFDFDPLRG
                     PVKDFTQTLMDEQGEVTKRVSGTLSEEGCFDSLELLDLENNTVVALVLDANYYRDAET
                     LEKRVRLQGKCQLAELPSAGVSWETDDNGFVIKASSKQMQMEYRYDDQGYPLGKTTKS
                     NDKTLSVSATPSTDPIKKLDYTAVTLLNNQRVGNVKQSCEYDSHANPVDCQLIIVDEG
                     VKPAVERVYTIKNTIDYY"
     gene            31297..31602
                     /locus_tag="IT892_001823"
     CDS             31297..31602
                     /locus_tag="IT892_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416103.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1161 domain-containing protein"
                     /protein_id="HAP3135047.1"
                     /translation="MKLSTCCAALLLALASPAVLAAPGSCERIQSDISQRIINNGVPE
                     SSFTLSIVPNDQVDQPDSQVVGHCANDTHKILYTRTTSGNVSAPAQSSQDGAPAEPQ"
     gene            31801..34227
                     /locus_tag="IT892_001824"
     CDS             31801..34227
                     /locus_tag="IT892_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HAP3135048.1"
                     /translation="MSKNERMVGISRRTLVKSTAIGSLALAAGGFSLPFTLRNAAAAV
                     QQAREKVVWGACSVNCGSRCALRLHVKDNEVTWVETDNTGSDEYGNHQVRACLRGRSI
                     RRRINHPDRLNYPMKRVGKRGEGKFERISWDEALDTIASSLKKTVEQYGNEAVYIQYS
                     SGIVGGNMTRSSPSASAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTTD
                     IENSKLVVMFGNNPAETRMSGGGITYLLEKAREKSNAKMIVIDPRYTDTAAGREDEWL
                     PIRPGTDAALVAGIAWVLINENLVDQPFLDKYCVGYDEKTLPADAPKNGHYKAYILGE
                     GDDKTAKTPQWASQITGIPEDRIIKLAREIGTAKPAYICQGWGPQRQANGELTARAIA
                     MLPILTGNVGISGGNSGARESTYTITIERLPVLDNPVKTSISCFSWTDAIDHGPQMTA
                     IRDGVRGKDKLDVPIKFIWNYAGNTLVNQHSDINKTHEILQDESKCEMIVVIENFMTS
                     SAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFLQPVTSEKFERKPIYWILSEVAKR
                     LGPDVYQKFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKKMGIYKRKDPNGHFVAYK
                     AFRDDPEANPLKTPSGKIEIYSSRLAEIARTWELEKDEVISPLPVYASTFEGWNSPER
                     RTFPLQLFGFHYKSRTHSTYGNIDLLKAACRQEVWINPIDAQKRGIANGDMVRVFNHR
                     GEVRLPAKVTPRILPGVSAMGQGAWHEANMSGDKIDHGGCVNTLTTLRPSPLAKGNPQ
                     HTNLVEIEKI"
     gene            34288..36711
                     /locus_tag="IT892_001825"
     CDS             34288..36711
                     /locus_tag="IT892_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416105.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HAP3135049.1"
                     /translation="MKIHTTKALMKAEISRRSLMKTSALGSLALASSAFTLPFSQMVR
                     AAEAPVEEKAVWSSCTVNCGSRCLLRLHVKDDTVYWVESDTTGDDVYGNHQVRACLRG
                     RSIRRRMNHPDRLKYPMKRVGKRGEGKFERISWDEALDTISDNLRRILKDYGNEAVHV
                     LYGTGVDGGNITNSNVPYRLMNSCGGFLSRYGSYSTAQISAAMSYMFGANDGNSPDDI
                     ANTKLVVMFGNNPAETRMSGGGVTYYVEQARERSNARMIVIDPRYNDTAAGREDEWLP
                     IRPGTDGALACAIAWVLITENMVDQPFLDKYCVGYDEKTLPANAPRNAHYKAYILGEG
                     PDGIAKTPEWAAKITSIPAEKIIQLAREIGSAKPAYICQGWGPQRHSNGEQTSRAIAM
                     LSVLTGNVGINGGNSGVREGSWDLGVEWFPMLENPVKTQISVFTWTDAIDHGTEMTAT
                     RDGVRGKEKLDVPIKFLWCYASNTLINQHGDINHTHEVLQDDSKCEMIVGIDHFMTAS
                     AKYCDILLPDLMPTEQEDLISHESAGNMGYVILAQPATSAKFERKPIYWMLSEVAKRL
                     GPDVYQTFTEGRSQHEWIKYLHAKTKERNPEMPDYEEMKTTGIFKKKCPEEHYVAFRA
                     FREDPQANPLKTPSGKIEIYSERLAKIADTWELKKDEIIHPLPAYTPGFDGWDDPLRK
                     TYPLQLTGFHYKARTHSSYGNIDVLQQACPQEVWINPIDAQARGIRHGDTVRVFNNNG
                     EMLIAAKVTPRILPGVTAIGQGAWLKADMFGDRVDHGGSINILTSHRPSPLAKGNPSH
                     SNLVQIEKV"
     gene            36722..37339
                     /gene="dmsB"
                     /locus_tag="IT892_001826"
     CDS             36722..37339
                     /gene="dmsB"
                     /locus_tag="IT892_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HAP3135050.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCDDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNAEKGHMTKCDGCYSRVAEGKQPICVESCPLRALEFGPIEELRQ
                     KHGTLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPEEV"
     gene            37341..38195
                     /locus_tag="IT892_001827"
     CDS             37341..38195
                     /locus_tag="IT892_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HAP3135051.1"
                     /translation="MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIV
                     RGMFFLWLLMGVGFIASVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWL
                     VAVIGKMPQALGKLWLLFSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLS
                     GPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVP
                     DYASLQVWRVVLLCAGLGCWLCPLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHM
                     TVGMAIAG"
     gene            38238..38852
                     /gene="dmsD"
                     /locus_tag="IT892_001828"
     CDS             38238..38852
                     /gene="dmsD"
                     /locus_tag="IT892_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707489.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat proofreading chaperone DmsD"
                     /protein_id="HAP3135052.1"
                     /translation="MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWET
                     QWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDS
                     TLALRQWMREKGIQFEMKQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
                     RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR"
     gene            39011..40303
                     /gene="clcB"
                     /locus_tag="IT892_001829"
     CDS             39011..40303
                     /gene="clcB"
                     /locus_tag="IT892_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001315626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated ClC-type chloride channel ClcB"
                     /protein_id="HAP3135053.1"
                     /translation="MHHLHIYPDLRTMFRRLLIATVVGILAAFAVAGFRHAMLLLEWL
                     FLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQ
                     TDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWI
                     ACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDAL
                     LYNVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGG
                     LIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVF
                     TPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEM
                     TGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAQHS"
     gene            complement(40256..40951)
                     /gene="bioD"
                     /locus_tag="IT892_001830"
     CDS             complement(40256..40951)
                     /gene="bioD"
                     /locus_tag="IT892_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310326.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HAP3135054.1"
                     /translation="MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGS
                     KETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANL
                     TEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIA
                     NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLA
                     MLRSVLAVDRVTV"
     gene            complement(41076..42296)
                     /gene="mlc"
                     /locus_tag="IT892_001831"
                     /gene_synonym="dgsA"
     CDS             complement(41076..42296)
                     /gene="mlc"
                     /locus_tag="IT892_001831"
                     /gene_synonym="dgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor Mlc"
                     /protein_id="HAP3135055.1"
                     /translation="MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAP
                     ASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALR
                     DLSSKLVVEESQELALKDDLPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTE
                     NGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQV
                     VIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILE
                     LAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFN
                     PQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKD
                     AMYNGSLLIRLLQG"
     gene            complement(42431..43324)
                     /locus_tag="IT892_001832"
     CDS             complement(42431..43324)
                     /locus_tag="IT892_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3135056.1"
                     /translation="MNIELRHLRYFVAVAEELHFGRAAARLNISQPPLSQQIQALEQQ
                     IGARLLARTNRSVLLTAAGKQFLADSRQILSMVDDAAARAERLHQGEAGELRIGFTSS
                     APFIRAVSDTLSLFRRDYPDVHLQTREMNTREQIAPLIEGTLDMGLLRNTALPESLEH
                     AVIVHEPLMAMIPHDHPLANNPNVTLAELAKEPFVFFDPHVGTGLYDDILGLMRRYHL
                     TPVITQEVGEAMTIIGLVSAGLGVSILPASFKRVQLNEMRWVPIAEEDAVSEMWLVWP
                     KHHEQSPAARNFRIHLLNALR"
BASE COUNT        11203 a        10981 c        10301 g        10842 t
ORIGIN      
        1 tgatgcgccc gtatgtagag cgcggcacgg tgaaagaatt tggcctgtgg gatgtggttc
       61 agcaaggcaa aatttcagtg tatgtcgcgg atgcattatt gaaaaaagga tcaatgaaaa
      121 cgggcgacaa gctggatatc aagggcgtag gtcaggttga agtctcgcca aacagcgttc
      181 agggctatga ctacgaagcg gatggtaatg gcatcgtact gttaccggag cgcgtgatat
      241 tcaacaaaga gaatatcggc aaatacgatt tctgatgtgc attacttaac cggagtaagt
      301 tatggcagat ttagacgata ttaaagatgg taaagatttt cgtaccgatc aaccgcaaaa
      361 aaatatccct tttaccctga aaggttgcgg tgcgctggat tggggaatgc agtcacgctt
      421 atcgcggata tttaatccga aaacgggtaa aaccgtgatg ctggcttttg accatggtta
      481 ttttcaggga ccgactaccg gacttgaacg cattgatata aatatcgccc cgctgtttga
      541 acatgccgat gtattaatgt gtacgcgcgg cattttgcgc agcgtagttc cccctgcgac
      601 caataggccg gtggtactgc gggcgtcagg tgcgaactct attctggcgg aattaagtaa
      661 tgaagccgtg gcgttatcga tggatgacgc cgtgcgcctg aacagttgcg cggtggcggc
      721 gcaggtttat atcggcagcg aatatgaaca tcagtcgatc aaaaatatta ttcagctggt
      781 tgatgccgga atgaaagtgg gaatgccgac catggccgtg actggcgtgg gcaaagatat
      841 ggtgcgcgat cagcgttatt tctcgctcgc gactcgaatc gccgctgaaa tgggggcgca
      901 aattatcaaa acctattatg tcgaaaaagg ttttgaacgg attgttgccg gatgtccggt
      961 acccattgtt attgctggcg gtaaaaaatt accggagcgc gaggcgctgg aaatgtgctg
     1021 gcaggctatc gatcagggcg cttctggtgt ggatatgggg cgtaatattt tccagtctga
     1081 ccatccggtg gcgatgatga aagccgtaca ggcggtggtt caccataacg aaacggctga
     1141 tcgggcatat gaactctatc tgagtgaaaa acagtaactg cggatctaag gagaagaatt
     1201 atgcacgtca cactggttga aattaacgtt catgaagaca aggttgacga gtttatcgaa
     1261 gtttttcgcc agaaccacct gggctctgta caggaagaag gcaatttgcg cttcgatgtc
     1321 ttacaggacc cggaagtgaa ttcgcgcttt tatatctacg aagcctataa agatgaagac
     1381 gcagtggcgt tccataaaac cacgccccac tacaaaacct gtgtcgcgaa actggaatct
     1441 ttaatgaccg ggccgcgtaa aaaacgtctg ttcaatggtt tgatgccgtg aggcgaattt
     1501 atcaatttta tctacaattg gggtaacgcg ctgacgggag taaaaaaatg tctgactgga
     1561 acccctcttt atatctacac ttttccgctg aacgatcgcg tccggcggtg gagctgcttg
     1621 ccagagtgcc gctggaaaat gtcgaatatg ttgccgatct tggctgtggc ccaggtaaca
     1681 gcaccgccct tctacaacaa cgttggcctg cggccaggat aacaggcatc gactcgtctc
     1741 cggcgatgat tgctgaagcg cgcagtgctt tgccagactg ccagttcgtg gaagcagaca
     1801 tccgcaactg gcaaccggta caggcactcg atctgatttt tgctaatgcc tcactgcaat
     1861 ggctgcccga ccactacgaa ttgtttcctc atctggtttc tttacttaat ccgcagggcg
     1921 tgctggcagt acagatgcca gataactggc tggagccgac ccatgtgctc atgcgcgaag
     1981 ttgcctggga acaaaactac ccggatcgcg ggcgtgagcc gttggctggc gttcatgctt
     2041 actacgatat tttgagcgaa gccggatgtg aggtcgatat ctggcgaacc acctactatc
     2101 accagatgcc gtcacaccag gcgattatcg attgggtgac tgccactgga ttacgtccgt
     2161 ggttacagga tctgaccgag agcgaacagc agctttttct taagcgctac catcagatgc
     2221 tggaagagca gtatccactg caagagaacg gacagatact gctggcattt ccgcgtctgt
     2281 ttattgttgc ccggcgtatg gagtaaatat cacgtcagct ggtaatgacg atcgggaaga
     2341 atttttgctg gaatttcggc ttcatcgttc atctgtaaca ggtcaatttc aatagcgttg
     2401 cagatggcat ccagtggtaa atcattgttt tcagtaccga acggatcttc cagttcttcc
     2461 gccagacaat ccagcgaaat aaaagtgtag gaaatcagca cagagataaa aggcgtcatg
     2521 taatgcaggt ccacgaccag cgcgaacggc agcatgatac aaaacagata aacggtacga
     2581 tgcaaaatca gggtgtaggc aaagggaatt ggcgtatagg caatgcgctc gcatcctgcc
     2641 aggaccgctg aaatatcatt aagccgatcg ttgaggctaa taaacaggat atctgaaagc
     2701 tgtccattgc ggcgctgaac cgccaaccat tctcccatta ttaacaagat acggttagct
     2761 ggagagttcg aagccagtac acgctgaaga tcttcagtct tgagataatg agccagcact
     2821 tccgcctgtg gctgtttgcg taatgtcatg cgtaaacagt gggcgaaagc gatttgcagc
     2881 cgggcaaact cccttacact tgccgaatcc ggcaatgtcg tttttacctc gcgcagtaac
     2941 gaccgtgagg caatcatcaa ctgcccccaa agttttcgcg cttcaacgta acgggcgtac
     3001 ccggcattat tacgaaaacc aagaaaaatg gcgatggcga caccgagaat gctgaacggt
     3061 gcgagggtga atttgatgcc cagatgcgtg taccagggca gcatgaaaat aacagcgata
     3121 gaaaagagaa aattgagtag taagcgcgag gatatcttgg ataatactga gccgtgccag
     3181 acaaaaatac ggcgcagcca gtgttgttgt ggacgaacaa tcatggttat cttcaggcgt
     3241 ggaaaagtcg ccctattaaa cgtgattacg atcacattct caagacgcta cttacaaatt
     3301 acctacaagc ttacaacatt agcaggcgct gcatgtggca cctgttaatg ataaaggcat
     3361 ataggatgtt gtaactaata tggtggaata agaaacccgg tcgaaaccgg gttcagaagt
     3421 aacggtgtta ttagcacaac ggacgtacag cttcgcgcat ccctttttcg agaatcgcat
     3481 ccaggtcatt agcaacctgc tcgaccagac caggcacttg cgtcaggtcc tgctcccagt
     3541 ggtctttttc tgccaaaaca atcgctacca gttcctgggt gccgataaca cggtcacgat
     3601 gctggctcca gagttgctga taacgttcca gccagtgtgc atcgtcctgt accggatatg
     3661 tttcgccgtt acgctcacca cgatagaacg caatcaatgc cgctaatgcg aaagtaaggc
     3721 gcgccggaag tgtgccgttt gccttctgcc ctgccagcag ctgtggcagg atgcgggtgc
     3781 ggaacttggt cataccgttg agcgcgatag acagcagctg atgcttaatg tacgggttac
     3841 ggaaacgccc ggtgactgca ctggcgaaag attccagttc atcacgaggc aaatccagta
     3901 ccggaataat ttcttcgtag atagcttttt caacgaatgc gcaaatttca gcatcgttca
     3961 tcgcttcacc tacggtatcc agccctgcct ggaacgccac cggcaccagc gcggtgtgcg
     4021 caccgttgag gattgccact ttgcgttctt tgtacggttt aatatcgtca acaatcagca
     4081 cgttgagcgg atatttgtcc agacgtagtt cagtcgctaa ggatttcggt ccctgaatca
     4141 caaacaggta aaagtgttca gcggtgtcga gaaaaccatc gtgataaccc agttcttctt
     4201 ccagtttagc cacttcatcg cgcggataac cggtaacgat acggtccacc agcgtagaac
     4261 agaagctgtt agcctgatcc agccattgaa taaatgcttc tggcagtgcc cactcttgcg
     4321 catagcgcag caccagttca cgcaacgcgt cgccattgta gtcaatcaac tcacacggaa
     4381 tgatgatcca acctttatcc agcgcaccgt tgaaatggct aaagcgttcg aacagcagac
     4441 gggtcagttt tgccggatag cttaccgctg gcgcgtcatc gaatttatcg cccgcatggt
     4501 agctgatacc cgcttcggtg gtgttagaga aaacaaagcg catttccggg ttgtgcgcca
     4561 gtttcaggaa ttcatcgtat tcactgtaga cgctgatttc acgattaacc gagcgaatca
     4621 gacgcgcgtc gctgaccgct tcccccttct cattcaggcc acggataatg gtggtgtaca
     4681 gaccatcctg cgtgctcagt gacggcggga atgaagtttc aatcggacga acaacgacca
     4741 cgccagaatt cagatcggtg tgctcattca ggagatcgat ttgccagtca acaaaggcgc
     4801 gcaggaagtt accttcacca aactgaatga tacgttctgg atactgtgca ccgggaaaat
     4861 cgcgacgatt tagtgttttc acaatgggtt cccttctgat tagtcataca acctgtttga
     4921 attggtacga caggttagca aactttaata cgccgaaccc ctgttttgat caactcctga
     4981 tgattaatga gcagttttat gagaaaagtg tggcgcggat catggtttaa tcgaggaaaa
     5041 acgccttttc ctggatcata aagtggtaga acacattgca ttcaaatcgc gcgtaatgaa
     5101 taaagatgtc agacaacttc ctcaccgtaa cgcatagtgc tggtacggtt gcgcccatct
     5161 ttcttcgagc gatacagaca cgtatcggct tcgaccatca atttattaaa gtcatcggtc
     5221 agcgttaggt acgatgcgcg accactaccg acgccaatac ttaccgtgag ataaagcgtt
     5281 ttttgttgcc aggtgaatgg ttgcagttca acgcctttac ggattttttc cgccattagc
     5341 agaccatcga caggattcac cgacggcact gcaacagcaa attcttcgcc gcccattcgc
     5401 gccaccagcc ccttatcacc gacaatcttc tgaatatgcc gggcaaacac gcttaacact
     5461 ttatcgccac attcatgtcc atagttatcg ttaatgcttt tgaaatagtc gatatcaagc
     5521 agcatgacag tcagatgttg tgtctgtttc agcgatggac ttttcagcgc ctcataaaga
     5581 ccggaccgtg agtaaacctg agtcagaaaa tcaaagtcgg ctcgcagcgc aacttgcttc
     5641 attagcgaat tgatcgctgc cacgctaaaa gaaaccataa ttgggcatat cgccatcgtg
     5701 gcaataccga gacgtgcgga gaacatttgc ggaatggaga acggcgaacc gaccgagata
     5761 tcaatcaccg aatttgccac cagtacgatt tccaccgcac cggtgacaaa ggtcaacaga
     5821 catgttacct gcggcgtata gcgcactgca caccagatta atgcaggcag cgggaacgcc
     5881 agactccccg ctccgccaat gactaccgag gcaataaccg acacaataag cgcgatggcg
     5941 ggcatcatct gttctgcttt aaagcgcggc agcactccag gaatagccaa cgtcagcata
     6001 caaggcacga tcaacacgcc cgttgagaat tgctcactga accagtccgc aagcaaaggc
     6061 cagaaatcca gactatcaat actgaccgaa ccaagatagc atgttcgctg acagcggcgg
     6121 caaataaagg taccctggga atgctatttt gtcgttttcc gcaattctca tggctgattc
     6181 atctgtacaa ccagccagtg atagattacc gccacgatat aacgttgttg ttcttcgctt
     6241 aacgaaacac cctgcggaat gttatgccac ttagccagac aaccgcgaca gcaggtcgcg
     6301 gtggcgtgct gagcgataaa caccggatgc ccgcgcatgg gggtttgctt accgtcatta
     6361 gccggtaatg ccggagcaag acgtttagcg acaaaatccg ccgcatgttg ttcgatgact
     6421 ggcgcgcctt tctccaggca atactgacgc tctttcatgc ccagacgaaa gcgagagcga
     6481 aattttgaac gggataaacg cgcgaagagt ggatcgagag actgcattaa taaaccgaac
     6541 gccctaactg tttcgtcaat tgttcaagga cggcaatacc cgcaagcgag ttacctgcat
     6601 catccagttc cggactccag acagcgatgg ccatttcatg cggaacaatc gccacaatac
     6661 cgccaccaac gccagatttc gccggtagcc ccacccgcca ggcaaactcc cccgcgttct
     6721 ggtacatacc actggtcgcc atcagcgcgt taatttgccg cgcctgcatt ggcgtcacca
     6781 ctggttcatc aatatgaata gctttcccct gattagccag aaagacaaac gtccgggcca
     6841 gctctacaca gctcattttc agagcgcagt aatgaaagta gttttgcaga acggttgtca
     6901 cgtcatgatg gaaattgcca aacgacttca tcagccaggc gatagccgca tttcgcgcgg
     6961 aatgttcaaa ttcggaacgc gctaccaccg tatcgtagga aatatcagac acaccgctta
     7021 agccgcgcac gacttccagc atacgttgcc gtggtgcgct taatcgccct tgcaacatat
     7081 cgcagaccac cagcgcaccg gcattaatga acggattacg cggtataccc tgctccattt
     7141 ccagttgcac taaggaattg aacggtgatc cagacggatc tttgccgacg cgttgccaga
     7201 tttcctcttc ggagtaatga cgcatggcga caacgagact cagcactttg gaaatagact
     7261 gaatggaaaa acgttcttgc gcgtctccgg cctgaaaaag ctgtccgtca acggtacaga
     7321 tagcaatccc caatcgggaa ccgtctactg tagccagcgc cggaatataa tccgcgactt
     7381 taccctgacc aatgagcggc cgcacttgcc gcaagatgtt ttctaaaatt gcattatcca
     7441 tggcgactgc cactttctac tcctggaccg caggtctgaa aagacctgcg agtatatcag
     7501 agctgaatat gtcgcgtcag atccggtctt tccacaccgt ctggatatta cagaattcgt
     7561 gtaagccgaa atgggaaagc tcacgaccaa agccactctt tttcacgcca ccaaaggcca
     7621 ctcgcgcgtc gctggcacaa taaccattga taaacacccc accgcattcc agacgtgccg
     7681 ccatctgtct ggcctgtgtt tcgtcagtgg taaaaatggt cgctgaaagg ccgaactcac
     7741 tatcattagc cagttccagt gcatgttctg catctttcgc aatggtgatt gccgcaacgg
     7801 ggccaaacat ttcttcccga aacgcggtca tttctggggt aacattcgcc agaaccgttg
     7861 gcggatagta gttacctgcc ccagccatct tttccccgcc cagtaacaaa cgcgcaccct
     7921 gcgccagggt tttctccacc tgatgatgca gctcatcacg taaatcaaaa cgagccattg
     7981 gtccgagagc gttctcttcg tcacggggat cgcccatttt caaggctgcc gcagctgcca
     8041 caaaacgttc ggtaaatgcc gaagcaattc cctcttcgat aataaagcgt tttgccgctg
     8101 cacatacctg tccggtattc tgataacgtc cggctaccgc cgctttcacc gccagttcca
     8161 gatcggcatc gttaagcaca ataaacggat ccgaaccgcc cagttccagt acgcattttt
     8221 tcagtgccgc tccagcctgt gcgccaatag ccgctcccgc acgaacactt ccggtcaccg
     8281 tgacagcagc aatgcgcgag tctttaatca tctgactgac accgtcgttg tcggcattca
     8341 gccagccata tacgccttgt gggatacccg catctttaaa cacctgggca atgagctgtg
     8401 cacagcccat cacattcggc gcatgtttaa gtaagtagcc gttacctgca agaatgatgg
     8461 gaacagcgcc acgcatcacc tgccataacg gaaaattcca cggcataatc gccagaatcg
     8521 tccccaacgg tcgatactca ataaccgcct gctgattttc caccagcgta ggttccgcct
     8581 tcagcattgc cggaccatgt tctgcatacc agtcacacaa attcgccgat ttcgccactt
     8641 cagcgcgcgc ctggttgatt ggtttgccca tttcgcgggt gatcatttgc gccatttctt
     8701 cgctacgagc gcgcagagcc ttaccgatat cacgcagttt ttcagcacga taatctatat
     8761 ttgtctcgcg ccagtcgcga aagcctgctg ccgccagctg aagtgcgttt tcgatatcgt
     8821 cagcgccagc ccacggcagc acagaaagtt gttcacccgt ggcaggattt atcgaaattg
     8881 catgagttgc cggagtaatg gtcatcgggg tatctccttt atgagtcatg gtatgaaaat
     8941 acgcagattt actcttgctt taaaatgaat aatattaagc cacttattca cgaatcgaga
     9001 atgctatgga tctgacccaa ctggagatgt tcaacgcggt tgccgaagct ggcagcataa
     9061 cccaggctgc agcaaaagtg catcgcgtgc cgtcgaatct cactacccgt ctgcgccagc
     9121 tggaaacaga actgggggtt gatctgttta ttcgcgagaa tcagcgttta cgtctctctc
     9181 ctgccgggca taacttttta cgctatagcc aacaaattct cgcgttagtg gatgaagcgc
     9241 ggagcgttgt cgctggcgat gagccgcaag gtttattttc tcttggttcg ctggaaagca
     9301 ccgctgcagt gcgcattcca gccacgctgg cggaattcaa ccgtcgttat cccaaaattc
     9361 agttttcact ttccaccggc ccttccggca ctatgctgga tggtgtactg gagggaaaac
     9421 tgaatgcggc gtttattgat ggacccatta accatactgc catcgacggg ataccggtat
     9481 accgcgagga actgatgatc gtcacgccac aaggatatgc gccagtaacc cgtgccagtc
     9541 aggttaatgg cagtaacatt tatgccttcc gcgccaattg ttcgtatcgt cgccacttcg
     9601 agagctggtt tcatgctgac ggtgccgctc cgggaactat ccatgagatg gagtcttatc
     9661 acggaatgtt ggcctgtgtg atcgcaggag caggcattgc gcttattccg cgctctatgc
     9721 tggaaagtat gccggggcat caccaggttg aagcgtggcc gttagctgag caatggcgtt
     9781 ggttaacaac ctggctggtc tggcgtcgtg gtgcgaaaac acgtccgctc gaggcattta
     9841 ttcaactgct ggatgtgcct gactcggcaa gacagggata tcaatgagct atttttgata
     9901 gttcttgcgg ttaatatgct ctatatagtg atgttccgat gacttatgac tatatggggc
     9961 aaatatggtt acgccagtaa gcatcagcaa ttacatatct cttcctgatg attttcccgt
    10021 acgtaatatt gcaccgcagg taaaagaagt tttaaaggat tttattgatg cacttagtac
    10081 aataatatgt aatgaagagt ggcgcacgtc tttaaatatc aactcagcca caaaaaagat
    10141 atttaataac cttgacaact tatcatatat tcagaggact tcttttcggg gtaacgacac
    10201 gctatacaat gaaaaggttc agtttaaact catttatccc gccaggaatg gaagacacaa
    10261 agaaaatatt gaatttcagg tagtaataaa tttaagccct atttatttag ataattttcg
    10321 ccatgatgga gaaattaata ttttttgcgc tcccaaccca aagcctgtca ctatggggcg
    10381 cgtatttcag accggcgtcg agcgtgtact ctttctgttt ctaaatgatt ttattgaaca
    10441 atttccaatg atcaaccctg gtgttcccat caaaagagcg catacaccac atattgaacc
    10501 cctgccttcg gatcaccata ccgctgcaga ttacttacgc cagtttgatt tgcttgtcct
    10561 gaattttatc tctcgcggta attttgtcat actcccccga ttatggaata actctgaggt
    10621 tcacagatgg ttcgtcaata aagatcctaa cttgatcacc gccattctcg acataacgga
    10681 cagcgaatta aaagaggatt tgttgcaaag cctgatggat tcattaggtt ctaacaaaca
    10741 tgtactaccc gaagtctgca tctgcttttt atccctttta gcagaacaag aatctcctca
    10801 ttttcagaac ttgtttttat ttttcgccaa tatgttattg cactatcacc aatttatgaa
    10861 tcccaatgaa agtgatttga atgacgtgtt gatgccagca tcattaagtg atgataaaat
    10921 tatcaaacat atggcgcgca ggaccctcaa actgtttgta aaaaatgaaa caccgccaaa
    10981 agttactcac gaagacctgg tgaaaaacag gcctcgctcc cctgtcagac cacctatacc
    11041 cgcaaccgcc aaaacgccag acctccctga acgtcattaa accgtgatgt taccgactct
    11101 ctgacgcgtg aaagaatcag cgtcagagaa acggaaaacg cgatccagat cacaaatgca
    11161 ttgtattcac atcattaacc gttttaagat catttcatca ctttttcgca actcacccga
    11221 taatctgtta tgacaacaaa cactgtttcc cgcaaagtgg cgtggctacg ggtcgttacg
    11281 ctggcagtcg ccgccttcat cttcaacacc accgaatttg tccctgttgg cctgctctct
    11341 gacattgcgc aaagttttca catgcaaacc gctcaggtcg gcatcatgtt gaccatttac
    11401 gcatgggtag tagcgctaat gtcattgcct tttatgttaa tgaccagtca ggttgaacgg
    11461 cgcaaattac tgatctgcct gtttgtggtg tttattgcca gccacgtact gtcgtttttg
    11521 tcgtggagct ttaccgttct ggtgatcagt cgcattggtg tggcttttgc acatgcgatt
    11581 ttctggtcga ttacggcgtc tctggcgatc cgtatggctc cggccgggaa gcgagcacag
    11641 gcattgagtt taattgccac cggtacagca ctggcgatgg tcttaggttt acctctcggg
    11701 cgcattgtgg gccagtattt cggttggcga atgaccttct tcgcgattgg tattggggcg
    11761 cttatcaccc ttttgtgcct gattaagtta cttcccttac tgcccagtga gcattccggt
    11821 tcactgaaaa gcctcccgct attgttccgc cgcccggcat tgatgagcat ttatttgtta
    11881 actgtggtgg ttgtcaccgc ccattacacg gcatacagct atatcgagcc ttttgtacaa
    11941 aacattgcgg gattcagcgc caactttgcc acggcattac tgttattact cggtggtgcg
    12001 ggcattattg gcagcgtgat tttcggtaaa ctgggtaatc agtatgcgtc tgcgttggtg
    12061 agtacggcga ttgcgctgtt gctggtgtgc ctggcattgc tgttacctgc ggcgaacagt
    12121 gaaatacacc tcggggtgct gagtattttc tgggggatcg cgatgatgat catcgggctt
    12181 ggtatgcagg ttaaagtgct ggcgctggca ccagatgcta ccgacgtcgc gatggcgcta
    12241 ttctccggca tatttaatat tggaatcggg gcgggtgcgt tggtaggtaa tcaggtgagt
    12301 ttgcactggt caatgtcgat gattggttat gtgggcgcgg tgcctgcttt tgccgcgtta
    12361 atttggtcaa tcattatatt tcgccgctgg ccagtgacac tcgaagaaca gacgcaatag
    12421 ttgaaaggcc cattcgggcc ttttttaatg gtacgtttta atgatttcca ggatgccgtt
    12481 aataataaac tgcacaccca tacataccag caggaatccc atcagacggg agatcgcttc
    12541 aatgccaccc ttgcccacca gccgcataat tgcgccggag ctgcgtaggc ttccccacaa
    12601 aataaccgcc accaggaaaa agatcagcgg cggcgcaacc atcagtaccc aatcagcgaa
    12661 ggttgaactc tgacgcactg tggacgccga gctaataatc atcgctatgg ttcccggacc
    12721 ggcagtactt ggcattgcca gcggcacaaa ggcaatattg gcactgggtt catcttccag
    12781 ctcttccgac ttgcttttcg cctccggtga atcaatcgct ttctgttgcg gaaagagcat
    12841 ccgaaaaccg ataaacgcga cgattaagcc gcctgcaatt cgcagaccgg gaatcgaaat
    12901 gccaaatgta tccatcacca gttgcccggc gtaatacgcc accatcatga tggcaaatac
    12961 gtacaccgag gccatcaacg actgacgatt acgttcggca ctgttcatgt tgcctgccag
    13021 gccaagaaat aacgcgacag ttgttaatgg gttagctaac ggcagcaaca ccaccagccc
    13081 caggccaatt gctttaaaca aatctaacat tggtggttgt tatcctgtgt atctgggtta
    13141 tcagcgaaaa gtataagggg taaacaagga taaagtgtca ctctttagct agccttgcat
    13201 cgcattgaac aaaacttgaa ccgatttagc aaaacgtggc atcggtcaat tcattcattt
    13261 gacttatact tgcctgggca atattatccc ctgcaactaa ttacttgcca gggcaactaa
    13321 tgtgaaaagt accagcgatc tgttcaatga aattattcca ttgggtcgct taatccatat
    13381 ggttaatcag aagaaagatc gcctgcttaa cgagtatctg tctccgctgg atattaccgc
    13441 ggcacagttt aaggtgctct gctctatccg ctgcgcggcg tgtattactc cggttgaact
    13501 gaaaaaggta ttgtcggtcg acctgggagc actgacccgt atgctggatc gcctggtctg
    13561 taaaggctgg gtggaaaggt tgccgaaccc gaatgacaag cgcggcgtac tggtaaaact
    13621 taccaccggc ggcgcggcaa tatgtgaaca atgccatcaa ttagttggcc aggacctgca
    13681 ccaagaatta acaaaaaacc tgacggcgga cgaagtggca acacttgagt atttgcttaa
    13741 gaaagtcctg ccgtaaacaa aaaagaggta tgacgatgtc cagacgcaat actgacgcta
    13801 ttaccattca tagcattttg gactggatcg aggacaacct ggaatcgcca ctgtcactgg
    13861 agaaagtgtc agagcgttcg ggttactcca aatggcacct gcaacggatg tttaaaaaag
    13921 aaaccggtca ttcattaggc caatacatcc gcagccgtaa gatgacggaa atcgcgcaaa
    13981 agctgaagga aagtaacgag ccgatactct atctggcaga acgatatggc ttcgagtcgc
    14041 aacaaactct gacccgaacc ttcaaaaatt actttgatgt tccgccgcat aaataccgga
    14101 tgaccaatat gcagggcgaa tcgcgctttt tacatccatt aaatcattac aacagctagt
    14161 tgaaaacgtg acaacgtcac tgaggcaatc atgaaaccac tttcatccgc aatagcagct
    14221 gcgcttattc tcttttccgc gcagggcgtt gcggaacaaa ccacgcagcc agttgttact
    14281 tcttgtgcca atgtcgtggt tgttcccccg tcgcaggaac acccaccgtt tgatttaaat
    14341 cacatgggta ctggcagtga taagtcggat gcgctcggcg tgccctatta taatcaacac
    14401 gctatgtagt ttgttctggc cccgacatct cggggcttat taacttccca cctttaccgc
    14461 tttacgccac cgcaagccaa atacattgat atacagcccg gtcataatga gcaccgcacc
    14521 taaaattgca gacccgttaa gcgttcatcc aacaatagtg ccgcacttgc cagtcctact
    14581 acgggcacca gtaacgataa cggtgcagcc cgccaggttt catagcgtcc cagtaacgtc
    14641 ccccagatcc cataaccaac aattgtcgcc acaaacgcca gatacatcag agacaagatg
    14701 gtggtcatat cgatagtaac cagactgtga atcatggttg cggaaccatc gagaatcagc
    14761 gaggcaacaa agaagggaat gattgggatt aaagcgctcc agattaccag cgacatcacc
    14821 gccggacgcg ttgagtgcga catgatcttt ttattgaaga tgttgccaca cgcccaacta
    14881 aatgctgccg ccagggtcaa cataaagccg agcatcgcca catgctgacc gttcagacta
    14941 tcttcgatta acaccagtac gccaaaaatc gctaaggcga tccccgccaa ttgtttgcca
    15001 tgcagtcgct ccccgaaagt aaacgcgcca agcatgatag taaaaaacgc ctgtgcctgt
    15061 aacaccagcg aagccagtcc agcaggcata ccgaagttaa tggcacaaaa aagaaaagca
    15121 aactgcgcaa aactgatggt taatccatac cccagcagca aattcagtgg tactttcggt
    15181 cgtgcgacaa aaaagatagc cggaaaagcg accagcataa agcgcaaacc ggccagcatc
    15241 agcggtggca tgttatgaag ccccactttg atgaccacaa aatttagccc ccatacgacc
    15301 actaccagta gcgccaacac cccatctttt cgcgacattc taccgcctct gaatttcatc
    15361 ttttgtaagc aatcaactta gctgaattta cttttcttta acagttgatt cgttagtcgc
    15421 cggttacgac ggcattaatg cgcaaataag tcgctatact tcggattttt gccatgctat
    15481 ttctttacat ctctaaaaca aaacataacg aaacgcactg ccggacagac aaatgaactt
    15541 atccctacga cgctctacca gcgcccttct tgcctcgtcg ttgttattaa ccatcggacg
    15601 cggcgctacg ctgccattta tgaccattta cttgagtcgc cagtacagcc tgagtgtcga
    15661 tctaatcggt tatgcgatga caattgcgct cactattggc gtcgttttta gcctcggttt
    15721 tggtatcctg gcggataagt tcgacaagaa acgctatatg ttactggcaa ttaccgcctt
    15781 cgccagcggt tttattgcca ttcctttagt gaataacgtg acgctggttg tgctcttttt
    15841 tgccctcatt aactgcgcct attctgtttt tgctaccgtg ctgaaagcct ggtttgccga
    15901 caatctttcg tccaccagca aaacgaaaat cttctcaatc aactacacca tgctaaacat
    15961 tggctggacc atcggtccgc cgctcggcac gctgttggtg atgcagagca tcaatctgcc
    16021 cttctggctg gcagctatct gttccgcgtt tcccatgctt ttcattcaaa tttgggtaaa
    16081 gcgcagcgag aaaatcatcg ccacggaaac aggcagtgtc tggtcgccga aagttttatt
    16141 acaagataaa gcactgttgt ggtttacctg ctctggtttt ctggcttctt ttgtaagcgg
    16201 cgcatttgct tcatgcattt cacaatatgt gatggtgatt gctgatgggg attttgccga
    16261 aaaggtggtc gcggttgttc ttccggtgaa tgctgccatg gtggttacgt tgcaatattc
    16321 cgtgggccgc cgacttaacc cggctaacat ccgcgcgctg atgacagcag gcaccctctg
    16381 tttcgtcatc ggtctggtcg gttttatttt ttccggcaac agcctgctat tgtggggtat
    16441 gtcagctgcg gtatttactg tcggtgaaat catttatgcg ccgggcgagt atatgttgat
    16501 tgaccatatt gcgccgccag aaatgaaagc cagctatttt tccgcccagt ctttaggctg
    16561 gcttggtgcc gcgattaacc cattagtgag tggcgtagtg ctaaccagcc tgccgccttc
    16621 ctcgctgttt gtcatcttag cgttggtgat cattgctgcg tgggtgctga tgttaaaagg
    16681 gattcgagca agaccgtggg ggcagcccgc gctttgttga tttaagtcga acacaataaa
    16741 gatttaattc agccttcgtt taggttacct ctgctaatat ctttctcatt gagatgaaaa
    16801 ttaaggtaag cgaggaaaca caccacacca taaacggagg caaataatgc tgggtaatat
    16861 gaatgttttt atggccgtac tgggaataat tttattttct ggttttctgg ccgcgtattt
    16921 cagccacaaa tgggatgact aatgaacgga gataatccct cacctaaccg gccccttgtt
    16981 acagttgtgt acaaggggcc tgatttttat gacggcgaaa aaaaaccgcc agtaaaccgg
    17041 cggtgaatgc ttgcatggat agatttgtgt tttgctttta cgctaacagg cattttcctg
    17101 cactgataac gaatcgttga cacagtagca tcagttttct caatgaatgt taaacggagc
    17161 ttaaactcgg ttaatcacat tttgttcgtc aataaacatg cagcgatttc ttccggtttg
    17221 cttaccctca tacattgccc ggtccgctct tccaatgacc acatccagag gctcttcagg
    17281 aaatgcgcga ctcacacctg ctgtcacggt aatgttgata tgcccttcag aatgtgtgat
    17341 ggcatggtta tcgactaact ggcaaattct gacacctgca cgacatgctt cttcatcatt
    17401 agccgctttg acaataatga taaattcttc gcccccgtag cgataaaccg tttcgtaatc
    17461 acgcgtccaa ctggctaagt aagttgccag ggtgcgtaat actacatcgc cgattaaatg
    17521 cccgtaggta tcattaacca atttaaatcg gtcaatatcc aacaacatta aataaagatt
    17581 cagaggctca gcgttgcgta actgatgatc aaaggattca tcaagaaccc gacgacccgg
    17641 caatcccgtc aaaacatcca tattgctacg gatcgtcagc aaataaattt tgtaatcggt
    17701 taatgccgca gtaaaagaaa gcaacccctc ctgaaaggcg tcgaaatgcg cgtcctgcca
    17761 gtgattttca acaatagcca gcattaattc ccgaccacag ttatgcatat gttgatgggc
    17821 agaatccatt agccgaacgt aaggtaattc atcgttatcg agtggcccca gatgatcaat
    17881 ccaccgacca aactggcaca gtccataaga atggttatcc gttatttctg gcttactggc
    17941 atctctcgcg accacgctgt gaaacatact caccagccac tggtagtggg catcgatagc
    18001 cttattgaga tttaacaaga tggcatcaat ttccgttgtc ttcttgatca ttgccactcc
    18061 tttttcacag ttccttgtgc gcgctattct aacgagagaa aagcaaaatt acgtcaatat
    18121 tttcatagaa atccgaagtt atgagtcatc tctgagataa cattgtgatt taaaacaaaa
    18181 tcagcggata aaaaagtgtt taattctgta aattacctct gcattatcgt aaataaaagg
    18241 atgacaaata gcataaccca ataccctaat ggcccagtag ttcaggccat caggctaatt
    18301 tatttttatt tctgcaaatg agtgacccga acgacggccg gcgcgctttt cttatccaga
    18361 ctgccactaa tgttgatcat ctggtccggc tgaacttctc gtccatcaaa gacggccgca
    18421 ggaataacga cattaatttc accgctctta tcgcgaaaaa cgtaacggtc ctctcctttg
    18481 tgagaaatca aattaccgcg tagtgaaacc gaagcgccat cgtgcatggt ttttgcgaaa
    18541 tcaacggtca ttttttttgc atcatcggtt ccgcgatagc catcttctat tgcatgaggc
    18601 ggcggtggcg ctgcatcctg ttttaaaccg ccctggtcat ctgccaacgc ataaggcatg
    18661 acaagaaaac ttgctaatac aatggcctga aatttcatac taactcctta attgcgtttg
    18721 gtttgactta ttaagtctgg ttgctatttt tataattgcc aaataagaat attgccaatt
    18781 gttataaggc atttaaaatc agccaactag ctgtcaaata tacagagaat ttaactcact
    18841 aaagttaaga agattgaaaa gtcttaaaca tattttcaga ataatcggat ttatatgttt
    18901 gaaaattatt atattggacg agcatacaga aaaagcaaat cacctttaca tataaaagcg
    18961 tggacaaaaa acagtgaaca ttaatagaga taaaattgta caacttgtag ataccgatac
    19021 tattgaaaac ctgacatccg cgttgagtca aagacttatc gcggatcaat tacgcttaac
    19081 taccgccgaa tcatgcaccg gcggtaagtt ggctagcgcc ctgtgtgcag ctgaagatac
    19141 acccaaattt tacggtgcag gctttgttac tttcaccgat caggcaaaga tgaaaatcct
    19201 cagcgtaagc cagcaatctc ttgaacgata ttctgcggtg agtgagaaag tggcagcaga
    19261 aatggcaacc ggtgccatag agcgtgcgga tgctgatgtc agtattgcca ttaccggcta
    19321 cggcggaccg gagggcggtg aagatggtac gccagcgggt accgtctggt ttgcgtggca
    19381 tattaaaggc cagaactaca ctgcggttat gcattttgct ggcgactgcg aaacggtatt
    19441 agctttagcg gtgaggtttg ccctcgccca gctgctgcaa ttactgctat aaccaggctg
    19501 gcctggcgat atctcaggcc agccattggt ggtgtttata tgttcaagcc acgatgttgc
    19561 agcatcggca taatcttagg tgccttaccg cgccattgtc gatacaggcg ttccagatct
    19621 tcgctgttac ctctggaaag gatcgcctcg cgaaaacgca gcccattttc acgcgttaat
    19681 ccgccctgct caacaaacca ctgataacca tcatcggcca acatttgcgt ccacagataa
    19741 gcgtaataac ctgcagcata tccgccacca aaaatatggg cgaaataact gctgcgatag
    19801 cgtggcggta tagcaggaag atccatattt tccgccacca gcgcccgcaa ttcaaaatca
    19861 tcgacatcct gcattgcttc gttttcttcc aggcaatgcc agcgcatatc gagaagtgcg
    19921 gcgctaagca gttcgctcat ctcataccct ttgttgaaca ggctggcatt acgcattttc
    19981 tgttgcagtt cgtcaggcat tgctgccccg ctctgataat gccgggcgta gcgagcgaat
    20041 acctgcggat gcgttgccca gtgttcgttg atttgcgacg gaaattcgac aaaatcacgc
    20101 ggcgtgttgg tgccggaaag cgtggcataa cgctggcggg caaaaaggcc gtgcagcgta
    20161 tgaccaaatt catggaataa ggttatgaca tcatcccaga gtaacaacgc aggctcaccg
    20221 gcagcgggtt tctgataatt gcagacgtta taaattaccg gatgtgtttt attaagcgtt
    20281 gattgctcaa caaaattgcc catccatgca ccgccgcttt ttgaatcacg ggcgaagaaa
    20341 tcaccgtaaa ataacgccag ccccacgcca ttatgatcaa aaatttccca cacacgaacg
    20401 tcaggatggt agacaggaat atcaaaacgt tcgacaaact taataccgaa gagctgattc
    20461 gcggtccaga atacaccttc atttaacacc gtgtttaatt caaaatatgg cttgagctgc
    20521 gcctcatcaa gatcaaattt ctcccgccgt acctgttccg cataaaatgc ccagtcccac
    20581 ggctgcgcgc taaacccgcc ctgctgctta tcgataaccg cctgtatgga ggctaattca
    20641 tcgctcgcac gttgacgcgc cgctggaaca atttcccgca taaagttaag tgctgcttca
    20701 ggtgtttttg ccatctgatc ggcgattttc catgcggcat aatgaggaaa accaagtagt
    20761 gttgcctgtt gtgcacggat ctccaccaga cgttgaatga tagcgcgggt atcattggca
    20821 tcattttttt ccgctcgcgt ccagcccgca ataaacagtt tttcacgcgt cgcacgatcg
    20881 cgcatttcgg caagcgccgg ttgttgggtg gtattcagca gcggaatcag ccatttgtta
    20941 tccagacctt tctcgcgagc cgcctctgcc gccagcgcaa tctcttgctc actcattcct
    21001 gccagctgcg cgatatcgtt cacaaccaga ccgccggatt tatttgctgc cagtaatcgc
    21061 tggttaaact ggctggtcag ggtcgcagct tctgtattca gtacttttaa ttttgcttta
    21121 tcagcttgcg caagtttggc tccggcaagg acaaaacgtt gatgaatcac ctccaccagg
    21181 cggatggatt cactatcaag ccccagggat tcacggcgct gccagacagc atctacccgc
    21241 gcgaataatt caccgttcag atagatatca ttagccagtt ccgccagttc agcggaaaac
    21301 tgctcgtcaa gacgctgtaa ttcatcattg gtatgcgccg cagtcatcgc aaaaaagacg
    21361 ctggtaacgc gggtaagtaa ttctccgctt tgttccagtg ccagaatagt attgttgaaa
    21421 tcaggcattt gcgggttaag cgcgatggca gcaatttctg cccgcttttg ctgcattccc
    21481 tcatcgaatg ccgggcgata gtgatgattg gcaatttgat caaaatgggg agccagatac
    21541 ggcagtgtgc tttgcacaag gaaaggattc attgttgtca ttttcttctc ctgaacgcga
    21601 ggtgttccat agcgtaggct tactgataac ggagtgcaat cttgcaatcc agtattaccc
    21661 gctcttaagc atcccgtgct atgttattga cacacaaaag cgttgaggaa cagtgagatg
    21721 atcgttttag taactggagc aacggcaggt tttggtgaat gcattactcg tcgttttatt
    21781 caacaagggc ataaagttat cgccactggc cgtcgccagg aacggttgca ggagttaaaa
    21841 gacgaactgg gagataatct gtatatcgcc caactggacg ttcgcaaccg cgccgctatt
    21901 gaagagatgc tggcatcgct tcctgccgag tggtgcaata ttgatatcct ggtaaataat
    21961 gccggcctgg cgttgggcat ggagcctgcg cataaagcca gcgttgaaga ctgggaaacg
    22021 atgattgata ccaacaacaa aggcctggta tatatgacgc gcgccgtctt accgggtatg
    22081 gttgaacgta atcatggtca tattattaac attggctcaa cggcaggtag ctggccgtat
    22141 gccggtggta acgtttacgg tgcgacgaaa gcgtttgttc gtcagtttag cctgaatctg
    22201 cgtacggatc tgcatggtac ggcggtgcgc gtcaccgaca tcgaaccggg tctggtgggt
    22261 ggtaccgagt tttccaatgt ccgctttaaa ggcgatgacg gtaaagcaga aaaaacctat
    22321 caaaataccg ttgcattgac gccagaagat gtcagcgaag ccgtctggtg ggtgtcaacg
    22381 ctgcctgctc acgtcaatat caataccctg gaaatgatgc cggttaccca aagctatgcc
    22441 ggactgaatg tccaccgtca gtaattttta tacccggcgt aactgccggg ttattgcttg
    22501 tcacaaaaaa gtggtagact catgcagtta actcactcac aagcaagaac gaatgaccgt
    22561 cgaaacgcaa cttaatccca cacagcctgt caatcagcag atttatcgta ttcttcgtcg
    22621 cgacattgtc cattgcctga ttgctccagg cacaccgttg tcggaaaaag aagtttctgt
    22681 tcgtttcaat gtgtcacgcc agccggttcg tgaagccttt attaaactgg cggaaaacgg
    22741 cctgattcaa attcgtccgc aacgtggcag ctacgtcaac aaaatttcca tggcccaggt
    22801 gcgcaacggc agttttatcc gtcaggccat tgagtgcgcg gtggcgcgtc gggcggcgag
    22861 catgattacc gaaagccagt gctatcaact ggaacaaaat cttcaccagc aacgcattgc
    22921 cattgagcgc aagcaactgg atgatttttt tgaacttgat gacaacttcc atcaactcct
    22981 gacgcagatt gccgactgtc aactggcgtg ggataccatt gagaacctga aagcgaccgt
    23041 tgatcgcgtg cgctatatga gtttcgacca cgtttctcca ccagaaatgc tgttacgcca
    23101 gcatcttgat attttctctg ccctgcaaaa acgtgatggc gatgcggtag aacgtgcaat
    23161 gacgcaacat ttgcaggaaa tcagcgaatc cgtgcgccag atccgccagg aaaacagcga
    23221 ctggtttagc gaagagtaat tcatttcctc tcatcccatc cggggtgaga gtcttttccc
    23281 ccgccttatg gctcatgcat gcatcaaaaa agatgtgagc ttgatcaaaa acaaaaaata
    23341 tttcactcga caggagtatt tatattgcgc ccgttacgtg ggcttcgact gtaaatcaga
    23401 aaggagaaaa cacctatgac gacctacgat cgtaaccgta acgcaatcac cactggcagc
    23461 cgtgttatgg ttagcggcac cggtcacact ggcaagatcc tgtcgattga tactgaaggt
    23521 ctgaccgctg agcaaatccg ccgcggaaaa accgtagttg ttgaaggttg tgaagagaaa
    23581 ctggcaccac tggacctgat tcgtctcggc atgaactaag cgtgtgaatg ccgccgatgg
    23641 cggcattgct tttttacttc acggaatatt ttgccacggt cgctttcgcg ccatgcgcta
    23701 ataaagacaa gtacgtttcc gtcactcttg cagtaaacaa actattgtct ggcaaatcat
    23761 caccaaagat cgccttaatc gccagcaatg actggacgcg cgctttccct tcggcactac
    23821 tttgtacagc cttctgaata acaggtaaca gtgggtcact gatttctatc ggatttccct
    23881 gttcatcaac accaccgaca taacgcatcc aacgcgcgac gcccagcgcc agcagatcga
    23941 acttgctgtc atgcgccaga tgccagcgaa cagaatccaa catccgctgt ggcaatttct
    24001 ggctaccatc catcgcaatc tgccaggttc gatgacgtaa cgccgggttg ctatagcgtg
    24061 caattaatcg gttagcgtaa tcttgcaaat caacgccctg cactttcaac gtcggcgctt
    24121 gttcctgcaa catcaagcca tacgccgcat aacgataatg ttcatcttcc atacagtcat
    24181 taatgtgctg atatcctgca agatacccca gatacgccag gaatgaatga ctgccgttga
    24241 gcatgcgcaa cttcatctct tcataaggca gcacatcgct aaccagttcg gctcccgctt
    24301 tttcccattc cggacgtccg gcaacaaagt tatcttctat tacccactgg cggaaaggtt
    24361 cacaggcaac gcccgcagga tcgcgcacac cggtaagttg ttcgattttc gccagcgtat
    24421 cctctgtcac tgcgggcaca atacggtcca ccattgttga tgggaaagtc acgttatctt
    24481 cgatccattg tgccagtttt acatcaacgg cttgtgcgta ggaagtgaca acgtcacgca
    24541 taacatgacc gttttctggc atgttgtcac atgacatgac ggtaaatgcg ggaagtcctg
    24601 ccgctttacg gcgagccagc gcctcaacaa tcacccctgt tgctgttttc ggctggtggg
    24661 gattttgcac gtcggcagct accatcgggt gatcgagcat taactgtccg gtcgccggag
    24721 agtggaaata ccctttttcg gtgattgtca gagagacaat cgcgatttgc ggttcacaca
    24781 tcgctgccaa cacggtttct aagccatcta tctgtacgtg caaggctttt ttaacgacgc
    24841 caacgacgcg agccgtccac acatcggccg acatttccgc aacggtataa agattatctt
    24901 gctgttgtaa atcggcaatt tgctgttcgc cgccgattaa gttgacctca taatatcccc
    24961 agtcactgaa atgttccgta gcaagaatat cggcatacac accctgatgc gcacggtgaa
    25021 atgcaccaaa gcctaaatga acaattcttg gagccaggtt attacgatca taaacaggga
    25081 gtgtcgcttt tgctgataac aaattatttc ccataacaat tccttaaata taaatatggc
    25141 aagctatatg ttttgttata tgaataaaaa tcccctctcc ggtaagagaa gggattaagg
    25201 gtttacagac ttctggaagg ttgcgcagct cttacaacac gcggttgatc ttccgcagcg
    25261 tcttccagcg cacttaaatc acggtctttc acctctggca ttttcagcgc agagattaaa
    25321 ccaatcactg aatatgccat gatcataatg gcgatcggat accaggattc cgtcatggtg
    25381 cagaaaatac ccgccaggat aggaccaaaa ccggaagcga taagaccacc aatttcttta
    25441 gaaatagcca tccgggtaaa gcggttttta cagccgaaca tttctgccat ggtaatgttt
    25501 tccagagcaa ataatcccag caccgcacag ttatgaatca caatcagtgc aaccataatg
    25561 gtgctcgggg catagctttt atctacaatg atagaaagca ttggccatgc cagcacaatc
    25621 gcggaggtat tcataataat atacgggatc cggcgaccaa ttttatcgga taaccaacca
    25681 aggaacggaa tggtcataaa gccgagaatc gaactgatca tcaatgcatc tgttggaatt
    25741 gctttgttaa acaataacgt ctgcactaaa tagcctgcaa ggaaagtctg aattaacccg
    25801 gagttacccg cctgaccaaa acgcagccct gttgccagcc agaaggattt gctctggaac
    25861 atgctaccag caggtgcagg ttttgctgtc ggttggttac tgtcgttaac cttctcaaag
    25921 accgggcttt ctttcagatt catacgcaac cagatagcaa agaccatcac gacaacactc
    25981 gccaggaacg gtatacgcca tccccacgcc agcagttcct ctttactgag aatgaagaac
    26041 ataaaggccc agattgccgt tgcgctcaag gttccgcagt tagttcccat agccacaaat
    26101 gaggagataa ttccgcgctt accttttggc gcatattccg ccagcatcgt accggcaccg
    26161 gaaatttccg cacctgcacc caacccctga ataatacgca acgtcaccag caagatgggt
    26221 gcaaaaacac caatctgtgc ataggtcggt aacacaccaa ttaaggtggt acagatcccc
    26281 atcatggtga tggtaataaa gagcactttt ttacgcccta ttctgtcgcc cattttgccg
    26341 aaaataaatg ctccgacaat acgcgccaca taacctgcac cgtaggttcc cattgccaga
    26401 attaacgcca ttgccgttga tgattcagga aaaaatattt catgaaacac taacgctgcg
    26461 ccgagcgaat ataactggaa atccataaat tcaagcgcag tgcccagcca tcccgatact
    26521 gctgctttca ccaaatcctt agtgcttctt tcgtgttttt ctattgtcat aatggttatc
    26581 tctaaaaaag aggtaagatg cgtactactt actcgccgtt attggtatta ttcagaaaaa
    26641 gtgagtaaga ctttgcagca atgtttttga tcctgttcaa ataaactaat ggcatcagca
    26701 acatgctgga aatcaaacgt atgggtaatt aatttttctg gtttaattaa ccctttactt
    26761 aaccagtcga taacgatcgg gaatttattt gcatttaagc gtgaagagaa aatagagagt
    26821 tcttttccgg taattccttg ctgaatcact tcagacggtt cactggagaa ccccatcaat
    26881 acaatacgtg ccgctggaga agccagcgtt acggcctctt tcaggataga aggatgacaa
    26941 gccgcatcga taattaatgt cggcttgatg cctttttcag tgaaaatctc gccaagcggt
    27001 gtctggctgt tattaatcgc ccagtcagcc ccgctctctt tcgctttttc cagtcgttca
    27061 tcaatgcgat cggcaacaat cacattttta acgttataga cgccttttaa tacctgaacg
    27121 atcgtcaggc cgattggacc ggcaccataa accagaacgg tatcattttc agtcggttga
    27181 ccatgtccgg ttacgttagc cgcaatggta aaaggttcga tcattaccgc atattgatcg
    27241 gccactgctt caggaatttt ccacgcattt tttgccggaa ccacggcata ttcactgaaa
    27301 ccaccgtcag cgtgcacacc taatacagcc agtgtcgtac aaacgttcgg tttacctata
    27361 gagcacggat agcaatgccc acagctgacc accggatcga cagcaacacg ttcaccgact
    27421 ctggcgcttt ccacgccttc acccactgca tcaatgacgc caaagaattc atgaccaatg
    27481 acgcgcggat atttcgcaaa aggattatgc ccacgataaa tatggctatc tgaaccacaa
    27541 attccggcaa gtttcacttt tactcgtact tcacccgctg acggggtggg tatttcacgt
    27601 tcgacaatcg ccagttgatt cggtttttca attaatatgc ttttcattat cttactcctt
    27661 accagttcca cagcgtgcca tcttccagac gtgcgactgg tagataagca ggttcatagg
    27721 gatatttcgc cgccagcttt tcatcgaatt cgataccaag acccggtttg tctcccggat
    27781 gcatatagcc gttatcgaaa gtccagttgt gcgggaagac ttcgagcatt tgttcggaat
    27841 aacccatgta ttcctggaca ccgaaattgg ggacccacag atcaaagtgc agcgccgcag
    27901 ccatgcagac tggtgacaaa tcggaaggac cgtgtgagcc agtacgtacc tgatacagcg
    27961 aagcaaaatc ggcaatccgg cgcataccgg taattccgcc tgcatgggtc agcgtggtgc
    28021 ggatataatc gatgagttgc tcttcaatca gttgtttgca gtcccagatg ctgttgaaga
    28081 cttcacccac tgcgatgggt gtgacggtat gttggcgaat gagacggaag cattcctggt
    28141 tttccgcagg cgtcgggtct tccatccaga acatgcgata atcttcaatg cttttaccaa
    28201 agcgcgccgc ttcaataggc gttaagcgat ggtgcatgtc atgcagcaaa tgttcattaa
    28261 aaccaaactt gttacgtacc gcgtcaaaca atttcggcat gaaatcgagg tatttctccg
    28321 tcgaccacag ctgctcttcc ggccactgtc ctttggttgc gggttcataa gccagacctt
    28381 tacctttcga catgccgtag gtggttttca taccagggat tccgcactgc acgcggatgg
    28441 ctttgaatcc aagctcttga tgacgggcat aatcatccag agcttcatca atactgtgac
    28501 cggtggtatg gcaataaacc atcacccctt cacgagacgc gccgccgagt aactggtaaa
    28561 gcggcatgtt ggcagctttg gctttaatat cccacagcgc catatcaacc gctgaaatgg
    28621 ccgacatcgt aaccggaccg cgacgccagt aagcaccttt atagaaaaac tgccagatat
    28681 cttcgatacg gtgcgcatcg cgaccaataa gctgcggaca aaggtgatcc tgcaaataag
    28741 aggccacgga aagctcacgt ccattgaggg tggcatcccc aaggcccgta ataccgtcct
    28801 cagtggtgat ttttaatgtg acgaaattac gccccggaca ggtaacaaaa acttcagcct
    28861 ttacgatctt catgttcgat tccttgcatc gcttgtcgtg atgcatgaaa tctacgcaac
    28921 tgagctacta ccatacaagt ataaagatcg aaaaaagccg gagtgatcac aaaaaaaggc
    28981 gtatatttgc gctgtgaatg gttgacaaaa gatgaaatag aatacctttt gtcagctgac
    29041 acttcctctt atcttattga taaaatggat ttatgttcct acgtgcgccc ccagcccgca
    29101 acaatgatca acatgccgca aagcgcaatc aacgcacccg tccagtcata aagagtcagt
    29161 ttcacgccat ccacaacgcg cagccacatc aacgccgtgc agacataaac gccaccataa
    29221 gccgcgtaaa cacgcccact cgccgctgga tgcaacgtta acaaccagac aaacagcgcc
    29281 agtgaaatcc ccgccggaag caacagccag atactggcgt ttcgttttaa ccacaaccag
    29341 ggcagaaagc atccaataat ttcacacagc gcagtagcaa aaaatagtaa cgttgtttta
    29401 atcatctttg tctcttattg acatcatgta tagttatagg gcgacataat atcatcaata
    29461 taaacaccct cctggtacgt tttgcgtccg cagtggatgg tgtagaatca cctttaatca
    29521 ttcatacagg gaatgaatta tgaaaatcac tctcagcaaa cgaatcggcc tgctcgctat
    29581 tctgctgcct tgcgcactgg cattgagcac aactgttcat gccgaaacta acaaactggt
    29641 gattgagtct ggcgacagtg cacaaagccg ccagcacgcc gctatggaaa aagagcaatg
    29701 gaatgacacg cgcaatctgc gccagaaagt gaataaacgc actgaaaaag agtgggataa
    29761 agccgacgcc gcttttgata accgcgataa atgtgagcaa agcgccaaca tcaatgccta
    29821 ctgggagccc aatactttgc gctgcctgga ccgtcgaact ggccgcgtta ttacccccta
    29881 acctgttatt gatttaagga atgtaaggac acgttatgcc aagcgcccac agtgttaagc
    29941 tacgcccgct ggagcgtgaa gatttacgct atgtacatca actcgacaat aacgccagtg
    30001 tgatgcgtta ctggtttgag gaaccctacg aagcctttgt tgaactctct gatctgtatg
    30061 ataagcatat tcacgatcag agcgaacggc gctttgtggt ggaatgtgac ggcgaaaaag
    30121 ccggtctggt ggagctggtg gaaattaacc atgttcatcg ccgcgcagaa tttcagataa
    30181 ttatctcccc ggagtatcag gggaaaggtc tggcaacccg tgccgccaaa ttagcaatgg
    30241 actatggctt taccgttctc aatctctata agctgtatct gatcgttgat aaagagaatg
    30301 aaaaagcgat tcacatttac cgcaagcttg gcttttcggt tgaaggtgaa ttgatgcacg
    30361 agttctttat taatggtcaa tatcgtaatg ccattcgcat gtgtatattc cagcatcagt
    30421 atctggcaga gcacaaaaca ccgggtcaga ctctcctgaa gccgaccgca caatagcatt
    30481 aataataatc gatcgtattt ttgatggtgt aaacccgttc gacggcgggt tttactcctt
    30541 catcaacaat gattagctga cagtccaccg gattagcgtg actgtcatat tcacagctct
    30601 gttttacatt accaacccgt tgattattca gtaaagtaac cgctgtgtaa tctaattttt
    30661 tgatcggatc cgttgatggc gtggcgctga cagataatgt tttgtcgtta cttttcgtgg
    30721 ttttacccag cggataaccc tgatcatcat agcgatattc catctgcatt tgtttgctgc
    30781 tggctttaat cacgaagcca ttatcatcgg tttcccaact caccccggca gaaggtaatt
    30841 ctgctagctg gcattttccc tgtaaacgta ctctcttctc cagcgtctcg gcatcacggt
    30901 aataattggc gtccagtacc agagcgacca cggtattatt ttccagatcc agtaattcga
    30961 gtgaatcaaa acagccttct tccgacaaag tcccagaaac acgtttcgtc acttcacctt
    31021 gctcatccat taatgtctga gtgaaatctt ttaccggacc acgcagcgga tcaaaatcga
    31081 attcattaga gaaactggcc atctcagggg taaatgaaag tgttacctct gtgcggtcac
    31141 atcctgtgag gaatatcgcg agtaagcatg gtagtaattt gtatttcaca acagtcacca
    31201 gagagtagag atgattctca atcatagtag caaatacagt actttacacg ttaaatgcta
    31261 tgcttaaaga agttatcttc gcgtaaggag cttatgatga aactctcaac ctgctgtgcc
    31321 gcgcttctgc tcgccctcgc ctcacccgcg gtactcgccg cgccgggatc ctgtgagcgc
    31381 atacagagcg atatatcaca gcgcattatc aataatggcg tacccgaaag cagcttcacg
    31441 ttaagtattg tacccaatga ccaggttgat cagcctgatt cccaggtcgt cggccattgc
    31501 gctaatgata cgcataaaat tctctatacc cgcaccacca gcggtaacgt ctctgctccc
    31561 gcgcagtcta gccaggatgg cgcgcctgcc gaaccgcagt aacacattat cgactgaacg
    31621 ccggatatga caaatccggc gatttgaaca tacaacataa tcccacctta ttactcatac
    31681 ccttctattg atatggatta ataattctta acccaaaatg ggtagactcc ctctattgtt
    31741 agcgcgctaa atattcaata tataaacttt tatataacga taaagaacag ggagtgagtt
    31801 atgtccaaaa atgaacgaat ggtgggcatc agccgcagaa cactcgttaa atctaccgcg
    31861 ataggttctc tggcgctggc tgcaggcggt ttttctttgc cgtttaccct gcgcaatgca
    31921 gcagcagcgg tacaacaggc ccgcgaaaaa gtggtctggg gtgcctgttc cgtcaactgt
    31981 ggtagccgct gtgcacttcg tctacatgtt aaagataatg aagtgacctg ggtggaaact
    32041 gacaataccg gcagcgatga gtacggcaac catcaggtac gcgcctgttt gcgcggtcgc
    32101 tccatccgcc ggcgtattaa tcatcccgat cgcttgaatt acccaatgaa acgcgtgggc
    32161 aaacgcggcg aaggcaaatt cgaacggatt agctgggatg aagccctgga tactatcgcc
    32221 agtagcctga agaaaaccgt cgaacaatat ggcaatgagg ctgtatatat tcagtactct
    32281 tcggggatcg ttggcggcaa tatgacccgc tcttcgccat cagcctcggc ggtcaaacgc
    32341 ctgatgaact gctacggcgg ttcactcaac cagtatggct cctacagcac tgcgcaaatt
    32401 tcctgtgcca tgccctacac ctacggcagt aatgatggca acagcaccac ggatattgaa
    32461 aacagcaagc tggtcgtgat gtttggtaac aacccggcag aaacccgcat gagcggtggt
    32521 ggcatcactt atcttcttga aaaagcgcgc gagaaatcga acgccaaaat gattgttatc
    32581 gatccgcgat ataccgatac ggctgccggt cgtgaagacg aatggctccc tattcgcccg
    32641 ggcaccgatg ccgcgctggt tgcgggtatt gcctgggtat tgattaacga aaatctcgtt
    32701 gatcaacctt ttctcgataa atactgcgtc ggctatgacg aaaaaacctt acccgcagat
    32761 gcacccaaaa atggtcacta taaagcctat attcttggtg aaggtgacga taaaacagcg
    32821 aaaacgccgc agtgggcttc gcaaattacc ggtatcccgg aggaccgtat catcaaactg
    32881 gcgcgtgaaa ttggcacagc aaaacccgct tatatctgcc agggctgggg gccacaacgc
    32941 caggcaaacg gcgaactgac tgcacgcgct attgctatgt tacctatttt gacgggcaat
    33001 gtcggcatca gcggcggaaa tagtggcgcg cgtgaatcga cctataccat taccatagaa
    33061 cgcctgccgg tgctggataa tccggtcaaa acgtcaatct cctgcttcag ctggacagat
    33121 gctatcgatc atggtccgca aatgacggca atccgcgacg gcgtccgcgg caaagataaa
    33181 ctggatgtgc ccattaagtt catctggaac tacgcgggaa ataccctcgt taatcagcat
    33241 tctgacatca acaaaacgca tgaaattctg caggacgaat cgaaatgcga aatgattgtg
    33301 gtcatcgaaa actttatgac ctcatcggca aaatatgccg acattctgct gccagacctg
    33361 atgaccgttg agcaggaaga tattattcct aacgactacg ccggtaacat gggatatctc
    33421 attttcctcc agcctgtcac cagcgaaaaa ttcgaacgca aaccgattta ctggatcctg
    33481 agtgaagtcg cgaaacgtct tggacctgac gtctatcaaa agttcacaga aggtcgcacg
    33541 caggaacaat ggttacaaca tctgtacgcc aaaatgcttg ccaaagatcc ggcgttaccg
    33601 tcttacgacg aactgaaaaa aatgggtatc tataagcgta aagatcccaa tggccatttt
    33661 gtcgcctaca aagcatttcg tgacgacccc gaggcaaatc cacttaaaac gccttccggt
    33721 aagattgaaa tttattccag caggctggcg gaaattgccc gtacctggga actggaaaaa
    33781 gatgaagtga taagcccatt gccagtttat gcctcaacct ttgaaggctg gaactcccct
    33841 gaacgtagaa ccttcccact gcaactgttt ggtttccatt acaaatcccg tactcactcg
    33901 acctacggca atattgatct cctgaaggct gcctgccgtc aggaggtgtg gatcaaccct
    33961 atagatgcgc agaaacgtgg gattgccaac ggcgatatgg tgcgggtgtt taaccatcgt
    34021 ggcgaagttc ggctaccagc caaagtaaca ccacgtattc tccctggagt tagcgctatg
    34081 ggccagggag cctggcacga ggccaatatg tctggcgata aaatcgacca tggcggctgt
    34141 gtgaatacgc taaccactct gcgcccttca ccactggcga agggaaaccc gcagcacact
    34201 aatctggtcg agatcgaaaa aatataaccc acgacaacca taaattctgg catgacattt
    34261 tgtttgaaaa gcaataagtg agtaatgatg aaaatccata ccacaaaggc gctcatgaag
    34321 gctgaaatca gccgtagaag tctgatgaaa acctccgcac ttggcagtct tgcgctggca
    34381 agcagtgctt tcactctgcc attttcccaa atggtccggg cggcagaggc tccggtagaa
    34441 gagaaagcgg tctggagttc ctgcaccgtt aactgcggga gccgctgtct gttacgtttg
    34501 catgtgaaag atgacaccgt gtactgggtg gagtctgata cgacaggtga cgacgtctac
    34561 ggtaatcatc aggttcgagc gtgtttacgc gggcgctcta tccgccgacg gatgaatcat
    34621 cctgataggt tgaaatatcc catgaagcgc gtcggcaagc gcggtgaagg taaatttgaa
    34681 cggataagtt gggacgaagc cctggatacc atcagtgata atcttcggcg gatcctgaaa
    34741 gattacggca atgaggctgt acatgtcctg tacggaacag gcgtagatgg cggaaacatc
    34801 accaactcaa acgtcccgta ccgtctgatg aactcttgcg gtggttttct cagtcgctat
    34861 ggcagctaca gtaccgcaca gatcagtgcc gcaatgagtt atatgttcgg tgccaatgat
    34921 ggcaacagcc cggatgatat cgccaatacg aaactggtcg ttatgttcgg aaataacccg
    34981 gcagaaacgc ggatgagcgg cggtggtgtc acttactacg tcgagcaagc ccgcgaacgt
    35041 tcaaacgcac gcatgatcgt catcgatcca cgttataacg acactgctgc cgggcgtgaa
    35101 gatgaatggc tgcccattcg ccctggcacc gatggcgcac tggcctgtgc gattgcctgg
    35161 gtactgatta ctgaaaacat ggtcgatcag ccatttctcg acaaatattg tgttggttac
    35221 gatgaaaaaa cgctgcccgc caacgcacca cgtaacgcgc attataaagc ctatattctg
    35281 ggcgaagggc ctgacggcat agctaaaacg ccggaatggg cagcaaaaat caccagcatc
    35341 ccggcagaaa aaattatcca gttggcacga gagatcggtt cagcaaaacc tgcttatatt
    35401 tgtcagggtt gggggccaca acgacattcc aacggcgagc aaacatcccg cgctattgcc
    35461 atgctttccg ttctcaccgg caacgtcggc ataaacggcg gcaactcagg cgtacgcgaa
    35521 ggtagctggg atctgggggt agaatggttc ccgatgctcg agaatcctgt taaaacgcag
    35581 atttccgtct ttacatggac agatgccatc gaccatggta cggaaatgac cgcgacccgt
    35641 gatggtgttc gtggaaaaga aaaactggat gtccccatca agtttttatg gtgctacgcc
    35701 agtaacacat tgatcaatca acatggcgac atcaatcaca cccatgaggt gcttcaggat
    35761 gacagcaagt gcgagatgat tgttggcatt gaccacttca tgacggcctc ggctaagtat
    35821 tgcgatatcc tgttgcccga cctgatgcca acagagcaag aagaccttat ctctcatgaa
    35881 tctgcaggga atatgggcta tgtgatcctc gcccaacccg caacctcagc aaaatttgaa
    35941 cgcaaaccca tctactggat gctgagtgaa gtcgccaaac gcttaggacc agacgtttat
    36001 caaaccttta ctgaaggtcg cagtcagcat gaatggatca aatatctcca tgcgaaaacg
    36061 aaggaacgta accctgagat gcccgactac gaggagatga aaacgaccgg gatctttaag
    36121 aaaaaatgcc cggaagaaca ctacgtcgct ttccgcgcat tccgtgaaga tccacaggca
    36181 aacccgttga aaacaccttc ggggaaaatc gaaatttatt ctgaacgact ggcgaagatt
    36241 gcagatacct gggaattgaa aaaagatgaa attattcatc cccttcctgc gtatacccca
    36301 ggttttgatg gctgggacga tcccctgcgg aaaacctatc cactgcagtt aacgggcttc
    36361 cattacaaag cgcgtaccca ctccagctac ggcaatattg atgtgttaca gcaggcctgc
    36421 ccacaagagg tgtggatcaa ccccattgat gctcaggcac gcggtatccg tcatggcgat
    36481 accgtgcggg tatttaacaa taatggagaa atgctgattg ccgcaaaagt gactccgcgt
    36541 attctgcctg gcgttaccgc catcgggcaa ggtgcgtggc ttaaagcgga tatgtttggt
    36601 gaccgggtcg atcacggcgg cagtatcaat attctgacct ctcaccgccc ttcaccgctg
    36661 gcaaagggaa acccgtcgca cagcaatctt gtccagatcg aaaaggttta aggagtagcc
    36721 catgaccaca caatatggat tttttatcga ttccagccgc tgtactggct gtaaaacctg
    36781 cgaactggcg tgcaaagatt ttaaagatct tggcccggaa gtcagtttcc gccgtattta
    36841 tgaatacgct ggcggcgact ggcaggaaga taatggcgtc tggcaccaga acgtgttcgc
    36901 ttattatctc tccatctcct gtaaccattg cgatgacccc gcatgtacaa aagtctgccc
    36961 cagcggcgca atgcataagc gtgaagatgg ctttgtggtg gttgatgaag atgtttgtat
    37021 cggctgccgc tactgccaca tggcttgtcc gtacggcgcg ccacagtaca atgctgaaaa
    37081 agggcacatg acgaagtgcg atggttgtta ttcgcgcgtc gccgagggga aacaacccat
    37141 atgtgtcgaa tcctgcccgc tgcgtgcact tgagttcggt ccaattgaag agctgcgcca
    37201 gaagcacggc actcttgctg ccgtcgcgcc actgccgcgc gcgcatttca caaaacccaa
    37261 tatcgttatc aaacctaacg ccaacagccg cccgaccggc gataccactg gttatctggc
    37321 taatccggag gaagtgtaaa atgggaaatg gatggcatga gtggccactg gttatcttta
    37381 ccgtattggg tcaatgcgta gtaggcgcgc tgattgttag cggaattggc tggttcgccg
    37441 ccaaaaatga cgcagaccgt cagcgtattg tccgtggcat gtttttcctc tggctgttga
    37501 tgggcgtcgg gtttattgcc tctgtcatgc acctgggatc gccactgcgg gcgtttaact
    37561 cgctgaatcg aatcggagct tctggtctga gtaacgagat tgctgccggt tccatatttt
    37621 ttgccgttgg cggattatgg tggctggtgg cagtcatcgg taaaatgccg caagcgttgg
    37681 ggaaactctg gttacttttc agcatggcgc tcggcgtcat tttcgtctgg atgatgacct
    37741 gcgtgtatca aatcgacacc gtgccaacct ggcataacgg ttacactacg ctggctttct
    37801 tcctgacggt attgttgagc ggtccaatac ttgctgccgc aattctgcgg gcagctcgcg
    37861 ttacatttaa taccacacca tttgccatca ttagcgttct ggcgctgatc gcttgtgccg
    37921 gggtgattgt gctgcaaggt ttgtctctgg cgtctattca ctcatccgtg caacaagcca
    37981 gcgcactggt accagattac gcctccttac aggtctggcg tgtggtattg ttatgcgcag
    38041 gtcttggatg ctggctttgc ccgctcattc gtcgccgtga acctcacgtt gccggactta
    38101 ttctggggct aatcctcata cttggcggtg agatgatcgg gcgtgtgctc ttttatggcc
    38161 tgcacatgac agtaggaatg gctattgcag gttaacaaat tggtgcgggg caacccgcac
    38221 atttcaggat gttaggaatg acccattttt cacagcaaga taatttttct gtcgcggcgc
    38281 gcgtgttggg cgcgctgttt tattacgctc cagagagtgc ggaagccgca cctctggttg
    38341 cggtactcac cagtgacggc tgggaaactc agtggcctct accagaagcg tcattagcgc
    38401 cgctggtgac ggcttttcag acacagtgtg aagagactca cgcccaggcc tggcagcgtt
    38461 tgtttgtcgg cccgtgggca ctgccgtctc cgccgtgggg gtcggtctgg ctggatcgcg
    38521 aatctgtgct gtttggcgat tcaacattgg cacttcgtca gtggatgcgc gagaaaggca
    38581 ttcagtttga aatgaagcaa aacgaaccgg aagatcattt tggttcactg ctgttgatgg
    38641 ctgcgtggtt ggcggagaat ggtcgccaga cagaatgcga agaattgctg gcatggcacc
    38701 tttttccgtg gtcaacacgt tttcttgatg tttttatcga aaaagcagaa caccctttct
    38761 accgtgcact gggtgaactg gctcgcttaa cgctggcgca atggcaatca caactgttaa
    38821 ttcctgtcgc ggttaaaccg ctgtttcgat aggatcaccg taatattgcc ggatggtgac
    38881 gattacgcgc aatccggcaa taataggtta cagcgtcacg tttttttatc tcttaaagca
    38941 cgcactgctt ttgcggctgg cctcttttgc cgcaaaatag tcgcccgtgt ttcattgccc
    39001 atttctgctc atgcatcatc tacacatcta tccggatctg cgcactatgt tccgccgtct
    39061 gcttatcgca acagtcgtcg gtattctcgc ggcctttgcc gttgccgggt ttcgtcatgc
    39121 gatgctgcta ctggagtggt tgttcctcaa taatgactcc ggcagtctgg tcaatgcagc
    39181 gacaaacctt tccccctggc gacggttgct aactccggcg ctcggcggac tggcggcggg
    39241 tttgttgctg atgggctggc agaaatttac ccaacaacgc cctcatgcgc cgaccgatta
    39301 tatggaagcg ttgcaaaccg atggacagtt cgattacgca gcaagcctgg ttaaatcgct
    39361 tgcctctctg ctggtagtaa ccagcggcag tgcaattggt cgcgaaggtg cgatgattct
    39421 tttagctgcc cttgccgcct cctgttttgc ccaacgtttt acgccacgcc aggagtggaa
    39481 attatggatc gcctgtgggg ccgcggcggg aatggctgcg gcctatcgtg ccccgcttgc
    39541 tggcagttta tttatagccg aagtgctgtt tggcactatg atgttggcct ctctcggccc
    39601 ggtgattatt tccgccgtcg tggcattgct ggttagcaat ctgattaatc atagcgacgc
    39661 gttactctac aacgtacaac tctcagtgac ggttcaggct cgtgactatg cgctgattat
    39721 cagtacaggt gtgctggcag gtctgtgcgg accactgttg ttaacgttaa tgaacgcctg
    39781 tcatcgtgga tttgtgagtc tcaaacttgc gccgccctgg caactggcac taggcgggtt
    39841 gatcgtgggt ctgctttccc tgttcacacc tgcagtgtgg ggcaacggct atagcaccgt
    39901 acaatccttt ttaaccgccc caccactgtt aatgatcatt gccgggatct tcctttgtaa
    39961 actgtgtgcc gtgctggcga gtagcggttc cggcgcaccc ggtggggtct ttacaccgac
    40021 gctatttatc ggtcttgcca ttggcatgtt gtatggtcgt agcctgggat tatggttccc
    40081 tgatggcgaa gaaattacac ttttactcgg attgaccggg atggcgacac tgttggcggc
    40141 gaccacgcac gcgccgatta tgtcgacgtt gatgatatgt gaaatgaccg gggagtatca
    40201 gctactcccc ggtttattga ttgcctgcgt aattgcgtcg gtaatttcgc ggacgttaca
    40261 ccgtgactct atctaccgcc agcacactgc gcagcatagc taagcggatg tattgcccca
    40321 gttcacgctg ttcggcgcgc ggcagataag gcagttcacc aatgagcggt gccggaagtt
    40381 ttttacccag cacatcaatg atttccgcat aatgcgccag tcctgggttg attcggttag
    40441 ccacccagcc aatgagcggc agcccgtcgt tggcgatcgc ctgagctgtt agcagtgcat
    40501 ggttaatgca accttcctga ataccgacaa ccatcaacac cggcagttgt tcctgcacta
    40561 cccattcaga gagtggacgc aaatcattca tcagactgcg ccagccgcca gtcccttcta
    40621 ccacgacatg atcgactttt tcggtcaggt ttgccaggcc gtttgaaatg agggtgtaat
    40681 tgattgggca actgtgcgcc acgctacttt cttcttcgct taacgcgata ggattaactg
    40741 cttcataagg cagttcgatg gttgaaacac tctgcaacac cagggcatct ttattacgca
    40801 gcccttcggg tgtctctttg ctccccttcg ctacgggttt atatcccgca accgtttttc
    40861 cctgggaggc taacgcttgt agcaatgcgc gggaaaccac cgttttccct acagaagtgt
    40921 ctgtaccggt aataaagaaa cgcttcagca tcactaactc caccgttatg cttcacaaat
    40981 ataaaccagg aaaataatta accttgaaag tctaagttat gctttcctgg cccaaattga
    41041 gatagcgcaa attttggtag aacagttaaa aaatgttaac cctgcaacag acgaatcaac
    41101 aaagaaccgt tatacatcgc gtcttttacc agtgcagcgc ctgccatcgt gccctggtta
    41161 gaaaactgag tactctcaac gctgatgtgc tgactatacg caggaagggc ctgctgacgg
    41221 atgctgtctg agatgaccgg gaagaggata tctgccgctt tacttaacgg tgagccaatc
    41281 agtatttttt gtgggttaaa taaattcacc atgatggcaa gaatgcgccc gacatgcgcg
    41341 cccaccccgg taatgatgtc ttttgccagt agatcgccgc gcaatgccgc ctgacacaat
    41401 gagtccacgg ttaacggttg tccatgtaac atcgagctca tggattgatt aagacgcagc
    41461 tgtgccagct caagaatact gtccacgctg gcgatggttt cgaggcagcc gtgattcccg
    41521 caataacagc gtttcccata cgggtcgacc tgtgtgtggc ctatttccac gagactactg
    41581 ctgcctgcgt gtagcagatg accatcggta atgacgcccg cccccacgtt gtgatcgata
    41641 accacctgaa tcacatcgcg cgccccgcgt gaggcaccaa acaaggcctc tgccatcgtc
    41701 catgcgctga tatcatgctg aatataaacc ggaacgccgg tatgctgctc cagcgcctcg
    41761 ccgagcggca tctcttttac atcctcgtag aacggcatgc gatgtacaat accattttcc
    41821 gtatcaataa ttcccggcaa ggttatggca atcgaagtta gacgctcaag ttttttctgg
    41881 tggcggataa aaaactgatc gatatgggaa ataatacgat ccagcaatgg caagtcatct
    41941 tttaacgcca gttcctgcga ctcttccacc accagtttgc tgctcagatc gcgcagagca
    42001 aggaaaatct ccccgcgact aatgcgcaga gaaagatagt gccaggcttc agtttcaacc
    42061 accagcccca ccgccggacg gccacggttc cccgcttctt tgatttccag ctcttgcacc
    42121 aggtgtgctt cgagcatctc acggacaatt ttagtgatac tggcaggagc cagttgcgcc
    42181 agacgggaaa gatcgatacg cgagactgga ccaagctgat caatcaggcg ataaaccgcg
    42241 cccgcgttgg tctgctttat ttgatcaatg tgcccaggct ggttttcagc aaccaccgca
    42301 tactccctat attttcgcgc tccgaaataa tctgtaggct atggtgaagc acttcaatac
    42361 gtgtcgtcaa atttttactt aggcatgtga ttaacagcac atttttcggg ctttttcgct
    42421 gaaatttccc tcacctgaga gcattcagca gatgaatacg aaagttacgc gcagccggac
    42481 tttgttcatg atgtttcggc cagaccaacc acatttcaga aaccgcatcc tcttcagcaa
    42541 tcggcaccca gcgcatttcg ttgagctgaa cacgtttaaa tgacgcaggc aaaattgaaa
    42601 cacccagacc ggcggaaacc agaccgatga tggtcattgc ctcgcccacc tcctgagtga
    42661 tgacgggcgt caaatggtaa cgtcgcatca gcccgagaat atcgtcatac agccctgtcc
    42721 cgacgtgcgg atcaaaaaag acaaagggtt ctttcgccag ttcagccagc gttacattcg
    42781 ggttatttgc caggggatga tcgtgcggga tcatcgccat aagcggttca tggacgatga
    42841 ctgcgtgttc aagcgactcc ggtaacgctg tgttacgcag caatcccata tccagcgttc
    42901 cttcaatgag cggagcgatt tgctcgcgag tgttcatttc gcgggtttgt aaatggacat
    42961 caggataatc acggcgaaac agcgataacg tatcggacac cgcccgaata aaaggagccg
    43021 acgaagtaaa accaatgcgc aactcccccg cttcaccctg atgcagcctt tcagcgcgag
    43081 cggcagcgtc atccaccata gacaggattt gccgactatc tgcaagaaac tgttttcctg
    43141 ctgccgtcag caatacactg cgattggttc gtgccagcag tcgggcacca atttgttgct
    43201 ccagcgcctg aatctgctga cttagcggcg gttgcgaaat attcaggcgg gcagcggcgc
    43261 gcccgaaatg cagctcttcc gcaacagcaa caaagtaacg cagatgacga agttcaatat
    43321 tcatatt
//
LOCUS       DACAOP010000030        42776 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.030, whole genome shotgun sequence.
ACCESSION   DACAOP010000030 DACAOP010000000
VERSION     DACAOP010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42776
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.030"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(30..863)
                     /gene="fdhD"
                     /locus_tag="IT892_001833"
     CDS             complement(30..863)
                     /gene="fdhD"
                     /locus_tag="IT892_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HAP3135057.1"
                     /translation="MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVA
                     LVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSS
                     RRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDF
                     QPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSS
                     RASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLS
                     N"
     gene            1057..4107
                     /gene="fdnG"
                     /locus_tag="IT892_001834"
     CDS             1057..4107
                     /gene="fdnG"
                     /locus_tag="IT892_001834"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:1642..1644,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HAP3135058.1"
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTR
                     ETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFI
                     HSESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLS
                     TGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTAAVADYYAPIR
                     SGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDYGFEDGLFTGYDAEKRKYD
                     KSSWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKDAFLKVCE
                     YIAETSAHDKTASFLYALGWTQHSVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEGQVNYWGNYPKFFVSM
                     MKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGYICQGFNPVASFPNK
                     NKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEVFRLPSTCFAEENG
                     SIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYSEQGGANPDQVLNMTWNY
                     AIPHEPSSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRDDGTTSCGCWIF
                     AGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQL
                     LKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPFPEHYEPFET
                     PLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWTKHALLNAI
                     LQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANGKDIDTIG
                     IPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     gene            4120..5022
                     /gene="fdxH"
                     /locus_tag="IT892_001835"
     CDS             4120..5022
                     /gene="fdxH"
                     /locus_tag="IT892_001835"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase subunit beta"
                     /protein_id="HAP3135059.1"
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKA
                     CQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMH
                     CSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKC
                     TLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAG
                     VGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHY
                     VGVGPNRADEEENNLHEEKDEERK"
     gene            5019..5654
                     /gene="fdoI"
                     /locus_tag="IT892_001836"
     CDS             5019..5654
                     /gene="fdoI"
                     /locus_tag="IT892_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HAP3135060.1"
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLM
                     QIMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVG
                     DTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
                     IVVIMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE"
     gene            5651..6580
                     /gene="fdhE"
                     /locus_tag="IT892_001837"
     CDS             5651..6580
                     /gene="fdhE"
                     /locus_tag="IT892_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HAP3135061.1"
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLREL
                     AENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKH
                     WQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFI
                     WAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLC
                     ETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCDTYLKILYQEKDPKIEAV
                     ADDLASLVLDARMEQEGYARSSINPFLFPGEGE"
     gene            complement(6910..7152)
                     /locus_tag="IT892_001838"
     CDS             complement(6910..7152)
                     /locus_tag="IT892_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135062.1"
                     /translation="MNSLAGIDMGRILLDLSNEVIKQLDDLEVQRNLPRADLLREAVD
                     QYLINQSQTARTSVPGIWQGCEEDGVEYQRKLREEW"
     gene            complement(7370..7588)
                     /locus_tag="IT892_001839"
     CDS             complement(7370..7588)
                     /locus_tag="IT892_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312842.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HAP3135063.1"
                     /translation="MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQ
                     QFPVRKAKGGRQKGEVVGVDDQCKEHKE"
     gene            complement(8441..9382)
                     /gene="fabY"
                     /locus_tag="IT892_001840"
                     /gene_synonym="yiiD"
     CDS             complement(8441..9382)
                     /gene="fabY"
                     /locus_tag="IT892_001840"
                     /gene_synonym="yiiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid biosynthesis protein FabY"
                     /protein_id="HAP3135064.1"
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAH
                     HQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGV
                     KRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQ
                     LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWG
                     LIWLMLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQM
                     QVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     gene            complement(9427..9864)
                     /gene="dtd"
                     /locus_tag="IT892_001841"
     CDS             complement(9427..9864)
                     /gene="dtd"
                     /locus_tag="IT892_001841"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAP3135065.1"
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANR
                     LCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRA
                     EALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     gene            complement(9861..10733)
                     /locus_tag="IT892_001842"
     CDS             complement(9861..10733)
                     /locus_tag="IT892_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor BrkB family protein"
                     /protein_id="HAP3135066.1"
                     /translation="MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSL
                     LSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMT
                     AVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAI
                     SSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAA
                     LLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYR
                     KLKQAAEQEEDDEP"
     gene            complement(10727..11326)
                     /gene="yihX"
                     /locus_tag="IT892_001843"
     CDS             complement(10727..11326)
                     /gene="yihX"
                     /locus_tag="IT892_001843"
                     /EC_number="3.1.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709685.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphatase"
                     /protein_id="HAP3135067.1"
                     /translation="MLYIFDLGNVIVDIDFNRVLGAWSDLTRIPLASLKKSFHMGEAF
                     HQHERGEISDEAFAEALCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHR
                     VVVLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLQAEGFSPSD
                     TVFFDDNADNIEGANQLGITSILVKDKTTIPDYFAKVLC"
     gene            complement(11425..12210)
                     /locus_tag="IT892_001844"
     CDS             complement(11425..12210)
                     /locus_tag="IT892_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418320.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP3135068.1"
                     /translation="MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRD
                     IRKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQTEEKKAIAEAVADYIPDGSTIFI
                     TIGTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPS
                     AASFVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHA
                     SAAVEIGNVAQVTALFTDELPPAALKSRLQDSQIEIILPQEDA"
     gene            complement(12244..13140)
                     /gene="yihV"
                     /locus_tag="IT892_001845"
     CDS             complement(12244..13140)
                     /gene="yihV"
                     /locus_tag="IT892_001845"
                     /EC_number="2.7.1.184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructose kinase"
                     /protein_id="HAP3135069.1"
                     /translation="MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATA
                     AVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVNTRYTKRYNQAKSSQSAIMVDTK
                     GERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLD
                     GDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGC
                     DWLENGGRQHQPAFKVDVVDTTGAGDVFHGALAVALATSGDLAESVRFASGVAALKCT
                     RPGGRAGIPDCDQTRSFLSLFV"
     gene            13308..14204
                     /gene="yihU"
                     /locus_tag="IT892_001846"
     CDS             13308..14204
                     /gene="yihU"
                     /locus_tag="IT892_001846"
                     /EC_number="1.1.1.373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfolactaldehyde 3-reductase"
                     /protein_id="HAP3135070.1"
                     /translation="MAAIAFIGLGQMGSPMASNLLQQGHQLRVFDVNAEAVRHLVDKG
                     ATPAANPAQAAKDAEFIITMLPNGDLVRNVLFGENGVCEGLSTDALVIDMSTIHPLQT
                     DKLIADMQAKGFSMMDVPVGRTSANAITGTLLLLAGGTAEQVERATPILMAMGSELIN
                     AGGPGMGIRVKLINNYMSIALNALSAEAAVLCEALNLPFDVAVKVMSGTAAGKGHFTT
                     SWPNKVLSGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAASREVYSQARAAGRGR
                     QDWSAILEQVRVSAGMTAKVKM"
     gene            14228..15106
                     /gene="yihT"
                     /locus_tag="IT892_001847"
     CDS             14228..15106
                     /gene="yihT"
                     /locus_tag="IT892_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructosephosphate aldolase"
                     /protein_id="HAP3135071.1"
                     /translation="MNKYTINDITRASGGFAMLAVDQREAMRMMFAAAGAPAPVADSV
                     LTDFKVNAAKALSPYASAILVDQQFCYRQVVEQNAIAKSCAMIVAADEFIPGNGIPVD
                     SVVIDRKINPLQIKQDGGKALKLLVLWRSDEDAQQRLDMVKEFNELCHSHGLVSIIEP
                     VVRPPRRGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGPQQELLCASQRLNDHI
                     NMPWVILSSGVDEKLFPRAVRVAMTAGASGFLAGRAVWASVVGLPDNELMLRDVCAPK
                     LQQLGDIVDEMMAKRR"
     gene            15123..16364
                     /gene="yihS"
                     /locus_tag="IT892_001848"
     CDS             15123..16364
                     /gene="yihS"
                     /locus_tag="IT892_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418316.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovose isomerase"
                     /protein_id="HAP3135072.1"
                     /translation="MKWFNTLSHNRWLEQETDRIFDFGKNSVVPTGFGWLGNKGQIKE
                     EMGTHLWITARMLHVYSVAAAMGRPGAYSLVDHGIKAMNGALRDKKYGGWYACVNDEG
                     VVDASKQGYQHFFALLGAASAVTTGHPEARKLLDYTIEIIEKYFWSEEEQMCLESWDE
                     AFSKTEEYRGGNANMHAVEAFLIVYDVTHDKKWLDRAIRVASVIIHDVARNNHYRVNE
                     HFDTQWNPLPDYNKDNPAHRFRAFGGTPGHWIEWGRLMLHIHAALEARCEQPPAWLLE
                     DAKGLFNATVRDAWAPDGADGIVYTVDWEGKPVVRERVRWPIVEAMGTAYALYTVTGD
                     RQYETWYQTWWEYCIKYLMDYENGSWWQELDADNKVTTKVWDGKQDIYHLLHCLVIPR
                     IPLAPGMAPAVAAGLLDINAK"
     gene            16478..17404
                     /locus_tag="IT892_001849"
     CDS             16478..17404
                     /locus_tag="IT892_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418315.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose-1-epimerase"
                     /protein_id="HAP3135073.1"
                     /translation="MSLIKVPCMQITNMHCSGQTVSLAAGDYHATIVTVGAGLAELTF
                     QGCHLVIPHKPEEMPLAHLGKVLIPWPNRIANGCYRYQGQEYQLPINEHSSKAAIHGL
                     LAWRDWQISELTATSVTLTAFLPPSYGYPFMLASQVVYSLNAHTGLSVEIASQNIGTV
                     AAPYGVGIHPYLTCNLTSVDEYLFQLPANQVYAVDEHANPTTLHHVDELDLNFTQAKK
                     IAATKIDHTFKTANDLWEMTITHPQQALSVSLCSDQLWVQVYSGEKLQRQGLAVEPMS
                     CPPNAFNSGIDLLLLESGKPHRLFFNIYGQRK"
     gene            17603..19639
                     /gene="yihQ"
                     /locus_tag="IT892_001850"
     CDS             17603..19639
                     /gene="yihQ"
                     /locus_tag="IT892_001850"
                     /EC_number="3.2.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovosidase"
                     /protein_id="HAP3135074.1"
                     /translation="MDTSRPQLLDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSG
                     IADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGR
                     LLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
                     TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALW
                     EDKATLRFECADTYISLLEKLTALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMR
                     NAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRIKQWNQEGVQFLAYI
                     NPYVASDKDLCEEAAQHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKK
                     NMIELGCGGWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEI
                     LFFMRAGSTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGY
                     TTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFARMTTVFT
                     TLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKYQYLLGRDILVAPVHEEGRS
                     DWTLYLPEDNWVHAWTGEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI"
     gene            19685..21070
                     /locus_tag="IT892_001851"
     CDS             19685..21070
                     /locus_tag="IT892_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418313.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3135075.1"
                     /translation="MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFY
                     TDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTL
                     LAIANFVGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
                     RQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYV
                     ETQPANPAQKPGLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDP
                     ILLSYMGFFSMGCIFIGVFLMPASVRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVSF
                     VAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGF
                     FPGWMLTQIGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRI
                     VEEIEARKRTA"
     gene            21113..22516
                     /locus_tag="IT892_001852"
     CDS             21113..22516
                     /locus_tag="IT892_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3135076.1"
                     /translation="MSDHNPLTLKLNLREKIAYGMGDVGSNLMLCIGTLYLLKFYTDE
                     LGMPAYYGGIIFLVAKFFTAFTDMLTGFLLDSRKNIGPKGKFRPFILYAAVPAALIAT
                     LQFIATTFCLPVKTTIATALFMMFGLSYSLMNCSYGAMIPAITKNPNERAQLAAYRQG
                     GATIGLLICTVAFIPLQSLFSDSTVGYACAALMFSIGGFIFMMLCYRGVKEHYVDTTP
                     TGHKASILKSFCAIFRNPPLLVLCIANLCTLAAFNIKLAIQVYYTQYVLNDINLLSWM
                     GFFSMGCILIGVLLVPLTVKCFGKKQVYLAGMVLWAVGDILNYFWGSNSFTFVMFSCV
                     AFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFFRKISAALAGFLPGIML
                     TQIGYVPNIAQSDATLQGLRQLIFIWPCALAIIAALTMGFFYTLNEKRFALIIEEINQ
                     RKNKEMATEEKTASVTL"
     gene            22584..23276
                     /gene="ompL"
                     /locus_tag="IT892_001853"
     CDS             22584..23276
                     /gene="ompL"
                     /locus_tag="IT892_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpL"
                     /protein_id="HAP3135077.1"
                     /translation="MKKINAIILLSSLTSASVFAGAYVENREAYNLASDQGEVMLRVG
                     YNFDMGAGIMLTNTYNFQREDELKHGYNEIEGWYPLFKPTDKLTIQPSGLINDKSIGS
                     GGAVYLDVNYKFVPWFNLTVRNRYNHNNYSSTDLSGELDNNDTYEIGTYWNFKITDKF
                     SYTFEPHYFMRVNDFNSSNGKDHHWEITNTFRYRINEHWLPYFELRWLDRNVEPYHRE
                     QNQIRIGTKYFF"
     gene            complement(23367..24632)
                     /locus_tag="IT892_001854"
     CDS             complement(23367..24632)
                     /locus_tag="IT892_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3135078.1"
                     /translation="MLTKKKWALFSLLTLCGGTIYKLPSLKDAFYIPMQEYFHLTNGQ
                     IGNAMSVNSFVTTVGFFLSIYFADKLPRRYTMSFSLIATGLLGVYLTTMPGYWGILFV
                     WALFGVTCDMMNWPVLLKSVSRLGNSEQQGRLFGFFETGRGIVDTVVAFSALAVFTWF
                     GSGLLGFKAGIWFYSLIVIAVGIIIFFVLNDKEEAPSVEVKKEDGASKNTSMTSVLKD
                     KTIWLIAFNVFFVYAVYCGLTFFIPFLKNIYLLPVALVGAYGIINQYCLKMIGGPIGG
                     MISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMACTLGFGAIVFTQRAV
                     FFAPIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDLNPGIIGYKIVFGIMA
                     CFAFSGAVVSVMLVKRISQRKKEMLAAEA"
     gene            complement(24734..25714)
                     /locus_tag="IT892_001855"
     CDS             complement(24734..25714)
                     /locus_tag="IT892_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HAP3135079.1"
                     /translation="MVTINNARKILQRVDTLPLYLHAYAFHLNMRLERVLPADLLDIA
                     SENNLRGVKIHVLDGERFSLGNMDDKELSAFGDKARRLNLDIHIETSASDKASIDEAV
                     AIALKTGASSVRFYPRYEGNLRDVLSIIANDIAYVRETYQDSGLTFTIEQHEDLKSHE
                     LVSLVKESEMESLSLLFDFANMINANEHPIDALKTMAPHITQVHIKDALIVKEPGGLG
                     HKACISGQGDMPFKALLTHLICLGDDEPQVTAYGLEEEVDYYAPAFRFEDEDDNPWIP
                     YRQMSETPLPENHLLDARLRKEKEDAINQINHVRNVLQQIKQEANHLLNH"
     gene            complement(25722..26432)
                     /locus_tag="IT892_001856"
     CDS             complement(25722..26432)
                     /locus_tag="IT892_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HAP3135080.1"
                     /translation="MAENQSTVENAKEKLDRWLKDGITTPGGKLPSERELGELLGIKR
                     MTLRQALLNLEAESKIFRKDRKGWFVTQPRFNYSPELSASFQRAAIEQGREPSWGFTE
                     KNRTSDIPETLAPLIAVTPSTELYRITGWGALEGHKVFYHETYINPEVAPGFIEQLEN
                     HSFSAVWEKCYQKETVVKKLIFKPVRMPGDISKYLGGSAGMPAILIEKHRADQQGNIV
                     QIDIEYWRFEAVDLIINL"
     gene            complement(26649..28472)
                     /gene="typA"
                     /locus_tag="IT892_001857"
     CDS             complement(26649..28472)
                     /gene="typA"
                     /locus_tag="IT892_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-dependent GTPase TypA"
                     /protein_id="HAP3135081.1"
                     /translation="MIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQERVMD
                     SNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF
                     DGPMPQTRFVTKKAFAYGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
                     PIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYV
                     GVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIVAI
                     TGLGELNISDTVCDTQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDR
                     LNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREI
                     DGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIG
                     FRSEFMTMTSGTGLLYSTFSHYDDVRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRG
                     KLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVVLVPPIRMTLE
                     QALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRAPKDD"
     gene            28845..30254
                     /gene="glnA"
                     /locus_tag="IT892_001858"
     CDS             28845..30254
                     /gene="glnA"
                     /locus_tag="IT892_001858"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="HAP3135082.1"
                     /translation="MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFF
                     EEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYD
                     RDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWN
                     SSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAG
                     QNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLS
                     KNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLA
                     YSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEA
                     MDKNLYDLPPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREE
                     DDRVRMTPHPVEFELYYSV"
     gene            30540..31589
                     /gene="glnL"
                     /locus_tag="IT892_001859"
     CDS             30540..31589
                     /gene="glnL"
                     /locus_tag="IT892_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HAP3135083.1"
                     /translation="MATGTQPDAGQILNSLINSILLIDDNLAIHYANPAAQQLLAQSS
                     RKLFGTPLPELLSYFSLNIELMQESLEAGQGFTDNEVTLVIDGRSHILSVTAQRMPDG
                     MILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
                     DPSLLEYTKVIIEQADRLRNLVDRLLGPQLPGTRVTESIHKVAERVVTLVSMELPDNV
                     RLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGER
                     YRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTS
                     WPGHTEFSVYLPIRK"
     gene            31601..33010
                     /gene="glnG"
                     /locus_tag="IT892_001860"
     CDS             31601..33010
                     /gene="glnG"
                     /locus_tag="IT892_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HAP3135084.1"
                     /translation="MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALA
                     SKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYL
                     PKPFDIDEAVALVERAISHYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRS
                     SISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFT
                     GANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRI
                     IAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLARHFLQVAARELG
                     VEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESTVAE
                     STSQMQPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAAR
                     LLGWGRNTLTRKLKELGME"
     gene            33122..33232
                     /gene="yshB"
                     /locus_tag="IT892_001861"
     CDS             33122..33232
                     /gene="yshB"
                     /locus_tag="IT892_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YshB family small membrane protein"
                     /protein_id="HAP3135085.1"
                     /translation="MLESIINLVSSGAVDSHTPQTAVAAVLCAAMIGLFS"
     gene            complement(33461..34834)
                     /gene="hemN"
                     /locus_tag="IT892_001862"
     CDS             complement(33461..34834)
                     /gene="hemN"
                     /locus_tag="IT892_001862"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAP3135086.1"
                     /translation="MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQA
                     VARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAPLFAG
                     RHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLR
                     AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQT
                     PESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAF
                     LTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGD
                     CYAQNQKELKQYYQQVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEKQW
                     DLHFADYFAEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKARM
                     QQFSRVI"
     gene            complement(35023..35532)
                     /gene="yihI"
                     /locus_tag="IT892_001863"
     CDS             complement(35023..35532)
                     /gene="yihI"
                     /locus_tag="IT892_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Der GTPase-activating protein YihI"
                     /protein_id="HAP3135087.1"
                     /translation="MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGS
                     RAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELL
                     ETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQE
                     DMMRLLRGN"
     gene            36114..36746
                     /locus_tag="IT892_001864"
     CDS             36114..36746
                     /locus_tag="IT892_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAP3135088.1"
                     /translation="MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALN
                     TLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEY
                     LEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLN
                     MVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE"
     gene            complement(37127..39913)
                     /gene="polA"
                     /locus_tag="IT892_001865"
     CDS             complement(37127..39913)
                     /gene="polA"
                     /locus_tag="IT892_001865"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAP3135089.1"
                     /translation="MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLN
                     MLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAM
                     GLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
                     GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEP
                     EKIAGLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELL
                     GLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETSVADEAPEVTATVISYDNYVTIL
                     DEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDA
                     PDQISRERALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILN
                     SVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQL
                     HLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAEL
                     EKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
                     KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVR
                     NEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAE
                     VFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGV
                     LEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADII
                     KRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPL
                     LVEVGSGENWDQAH"
     gene            39915..40157
                     /locus_tag="IT892_001866"
     CDS             39915..40157
                     /locus_tag="IT892_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135090.1"
                     /translation="MSVPVYQIMGKGCHRQDENMSFSPLFVKIFCRSSGSLANRHVDN
                     FVHKLFTSLLIYYHAFYSMMFVFVFHAVKNKSIPNN"
     gene            40277..41209
                     /locus_tag="IT892_001867"
     CDS             40277..41209
                     /locus_tag="IT892_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAP3135091.1"
                     /translation="MANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVK
                     LLLPVPVIWRKVSRFCDFMMYCWCEGLAVLLHLNPHLQWEVHGLEGLSKKNWYLLICN
                     HRSWADIVVLCVLFRKHIPMNKYFLKQQLAWVPFLGLACWSLDMPFMKRYSRAYLLRH
                     PERRGKDVETTRRSCEKFRLHPTTIVNFVEGSRFTQEKHQQTHSTFQNLLPPKAAGIA
                     MALNVLGKQFDKLLNVTLCYPDNNRQPFFDMLSGKLTRIVVHVDLQPIADELHGDYIN
                     DKSFKRHFQQWLNSLWQEKDRLLTSLMSSQRQNK"
     gene            complement(41250..42680)
                     /locus_tag="IT892_001868"
     CDS             complement(41250..42680)
                     /locus_tag="IT892_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418298.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HAP3135092.1"
                     /translation="MIRKSATGVIVALAVIWGGGTWYTGTQIQPGVEKFIKDFNDAKK
                     KGEHAYDMTLSYQNFDKGFFNSRFQMQMTFDNGAPDLNIKPGQKVVFDVDVEHGPLPI
                     TMLMHGNVIPALAAAKVNLVNNELTQPLFIAAKNKSPVEATLRFAFGGSFSTTLDVAP
                     AEYGKFSFGEGQFTFNGDGSSLSNLDIEGKVEDIVLQLSPMNKVTAKSFTIDSLARLE
                     EKKFPVGESESKFNQINIINHGEDVAQIDAFVAKTRLDRVKDKDYINVNLTYELDKLT
                     KGNQQLGSGEWSLIAESIDPSAVRQFIIQYNIAMQKQLAAHPELANDEVALQEVNAAL
                     FKEYLPLLQKSEPTIKQPVRWKNALGELNANLDISIADPAKSSSSTNKDIKSLNFDVK
                     LPLNVVTETAKQLNLSEGMDAEKAQKQADKQISGMMTLGQMFQLITIDNNTASLQLRY
                     TPGKVVFNGQEMSEEEFMSRAGRFVH"
BASE COUNT        10485 a        10975 c        10540 g        10776 t
ORIGIN      
        1 tttaatatat ttcgcaggac ttattttaat taattgctca aacgctgcgg atgggtataa
       61 accgttgccc gacccggttt acaaaaacct accagtgtca gattacagcg ctcagccact
      121 tctacagcaa gcgtggtcgc ggcagacacc gcaaacaaaa tctctacgcc gcacatcgcc
      181 gacttttgca ccatttcata actggcacga ctggaaacca gtaccgcacc ttgctgccag
      241 ctttcccctt cttgtgaccg gcggcctaac agtttgtcca gcgccacatg gcgacccacg
      301 tcttcatgcc cgccgaccag ttcgccagat ggcaacatcc aggcagcggc gtgagtacaa
      361 ccagtcagtt gccccactgg ctgaaaatcg ttgagatgac gtaatgcatc atccagtttg
      421 ttgagatcaa acgtctgggt gaacggtagc ggctgcaccg gttttccgat gtcattaagt
      481 tgctccacgc cgcatacgcc acagcccgta cgtcccgcca gcgcccggcg gcgctccttc
      541 aaccccataa agcggcggct ggaaagctca atttgtactt caagaccatt acaggaagga
      601 acgacatcca tgccgaagat atcgcgcgga ctttcgataa tcccctcgga aagcgaaaaa
      661 ccgagcgcaa agtactcaag gtctttgggc gacgccatca tcaccacatg cgaaatgccg
      721 ttgtagacca gcgcaacggg aacttcttcc gcgacctcat ctaaccgtgg gtgttgtaaa
      781 tcatcacgcc gccataactc aatttgacga acacctgtga tatttgtcac attttcgatt
      841 tcttttcgct gtgttttttt cactttctct taaccagata agaacacaca caccaacatt
      901 atggtattct gttacaaacc cttcctggat ggagggaaat tgagccaatt ctggaccttt
      961 gcggcccctt ccgcaaagaa aaataactcc cactccctgc acacgcagca agcgaatgta
     1021 aatgggacgt gacaatgtcg aaacaaggag caatccatgc aggtcagcag aaggcagttc
     1081 tttaagatct gcgctggcgg tatggcaggc accacggcag cggcactggg ttttgcaccc
     1141 agcgtagcac tcgcggaaac ccggcagtat aaactgctgc gcacccgcga aacccgtaat
     1201 acctgcacct attgttccgt aggctgtggg ctgttgatgt acagcctcgg tgacggagca
     1261 aaaaacgcca aagcatctat cttccatatc gaaggcgatc cggatcaccc ggtcaaccgc
     1321 ggtgcacttt gtccgaaagg cgctggcctg gtggatttca tccactccga aagccgtctg
     1381 aagtttccgg aataccgtgc gccaggttct gataaatggc agcaaatcag ttgggaagag
     1441 gcgtttgatc gcatcgccaa actgatgaaa gaagaccgcg atgctaacta cattgcgcaa
     1501 aacgccgaag gcgtgactgt taaccgctgg ctctccaccg ggatgctgtg tgcttccgcg
     1561 tcgagtaacg aaaccggcta tttaacgcaa aaattctccc gcgcgctggg tatgctcgcg
     1621 gtcgacaacc aggcgcgtgt ctgacacgga ccaacggtag caagtcttgc tccaacattt
     1681 ggtcgcggtg cgatgaccaa ccactgggtc gacatcaaga acgccaacct cgtcgtggtg
     1741 atgggcggta acgccgctga agctcacccg gtcgggttcc gctgggcgat ggaagccaaa
     1801 attcacaacg gcgcgaagct gattgtgatc gatcctcgct ttacgcgtac ggcggcggta
     1861 gctgactact atgcccctat tcgttccggt actgacattg ctttcctgtc aggcgtattg
     1921 ctgtacctgc tgaacaatga aaaattcaac cgcgaataca ccgaagccta taccaacgcc
     1981 agcctgatcg tgcgtgagga ttacggcttt gaagatggcc tgttcaccgg ctacgacgcg
     2041 gaaaaacgca agtacgataa atcctcctgg acttatgaac tggacgaaaa cggcttcgcc
     2101 aaacgcgata ccacgctgca acatccgcgc tgcgtgtgga acttgctgaa acagcacgtt
     2161 tcccgctaca cgccagatgt ggttgaaaac atctgtggta cgccaaaaga cgcgttcctg
     2221 aaagtctgcg aatacatcgc agaaaccagt gctcacgata aaactgcctc gttcctgtat
     2281 gccctcggct ggacgcaaca ctccgttggt gcgcaaaaca ttcgtacgat ggcgatgatc
     2341 cagctgctgc tcggcaatat ggggatggca ggcggcggcg ttaacgccct gcgcggtcac
     2401 tccaatattc aggggctgac ggacctgggg ctgctgtcgc agagcctgcc aggttacatg
     2461 acgctgccaa gcgagaagca gaccgatctg caaacctacc ttaccgccaa cacgccaaaa
     2521 ccgctgctgg aaggccaggt aaactactgg ggcaactacc cgaaattctt cgtctctatg
     2581 atgaaggcct tctttggtga taaagcgacg gcggaaaata gctggggctt tgactggttg
     2641 ccgaagtggg ataaaggcta cgacgtcctg caatacttcg agatgatgaa agagggcaag
     2701 gtcaatggct atatctgcca gggctttaac cctgttgcct cattcccgaa caaaaacaaa
     2761 gtgatcggtt gtctgtcgaa actgaagttc ctcgtcacca tcgacccact gaacactgaa
     2821 acctctaact tctggcagaa ccacggtgag ctgaacgaag ttgactcgtc gaagatccag
     2881 accgaagtgt tccgtctgcc atcgacctgc ttcgcggaag agaacggttc tatcgttaac
     2941 tcaggtcgct ggttacagtg gcactggaaa ggtgcggacg ccccggggat tgcgctgact
     3001 gacggcgaga tcctctccgg tatcttcctg cgcttgcgca agatgtattc cgaacagggt
     3061 ggcgcgaacc cggaccaggt gctgaacatg acatggaact acgccattcc gcatgagcca
     3121 tcttcagaag aagtggcgat ggagagcaac ggtaaggcgc tggccgatat taccgatccg
     3181 gcaaccggtg cggttatcgt caagaaaggc caacaactta gttcgttcgc ccaattgcgc
     3241 gatgacggta caacctcctg tggctgctgg attttcgccg gtagctggac gccggaaggc
     3301 aaccagatgg cacgccgtga taacgccgat ccgtctggcc tcggtaacac gctgggctgg
     3361 gcatgggcat ggccgcttaa ccgccgcatt ctgtataacc gcgcctccgc agatccgcag
     3421 ggtaacccgt gggatccgaa gcgtcagttg ctgaaatggg acggcactaa gtggaccggc
     3481 tgggatattc cggactacag cgcagcgcct ccgggtagcg gcgtcgggcc gtttatcatg
     3541 cagcaggaag gcatggggcg tctgtttgcc ctcgataaga tggcggaagg tccgttcccg
     3601 gaacactacg agccgtttga aacgccgctg ggaactaacc cgctgcatcc aaacgttatc
     3661 tcgaacccgg ctgcacgtat ctttaaagac gacgccgaag cattgggtaa agccgataag
     3721 ttcccgtatg tcggaaccac ctatcgtctg accgagcact tccactactg gaccaaacac
     3781 gcgctgttga acgcgatttt gcagccagag cagtttgtgg aaatcgggga gtcgctggcg
     3841 aataaacttg gcattgccca gggcgatacc gtgaaagtct cctccaaccg tggctatatc
     3901 aaagccaaag cggtggtgac caaacgtatt cgcacgctga aagcgaacgg caaagatatc
     3961 gataccatcg gtattccgat tcactggggc tatgaaggcg tagctaaaaa aggctttatt
     4021 gccaatactt taacgccatt cgttggtgat gcgaacacgc agacgccgga gtttaagtcc
     4081 ttccttgtga atgtggaaaa ggtgtaacgg agacgacata tggcttatca atctcaagat
     4141 atcattcgtc gttccgcgac taacggtctg acccccgcgc ctcaggcgcg ggacttccag
     4201 gaagaagtgg cgaaactcat cgacgttacc acctgtatcg gctgtaaagc ctgtcaggtg
     4261 gcgtgttcag agtggaacga cattcgcgat accgtcggca ataacattgg ggtgtacgac
     4321 aaccccaatg atttaagcgc caaatcgtgg acggtaatgc gcttctcgga agtggagcag
     4381 aacgacaaac tggaatggct gatccgcaaa gacggctgta tgcactgttc cgatccaggc
     4441 tgcctgaaag cgtgcccggc ggaaggtgca attattcagt atgccaacgg tatcgtcgac
     4501 ttccagtccg agcagtgcat tggctgcggt tattgcattg cgggctgtcc gttcgacatt
     4561 ccgcgcctca acccggaaga caaccgcgtc tacaaatgta cgctgtgcgt tgaccgcgtg
     4621 gtggttgggc aagaaccagc ctgcgtgaag acctgcccaa cgggcgcgat tcacttcggt
     4681 acgaaagagt cgatgaaaac gctggcgagc gagcgcgttg ctgagctgaa aacccgcggt
     4741 tacgacaatg cgggtctgta cgatccggca ggcgtcggtg gtacacacgt catgtacgtg
     4801 ctgcaccatg ctgacaagcc aaatctgtat catggcttgc cggagaaccc ggaaatcagc
     4861 gaaaccgtga aattctggaa aggcatctgg aaaccgctcg cggctgttgg ctttgcggct
     4921 acctttgcgg ccagtatctt ccactacgtg ggtgtcggtc cgaaccgtgc ggatgaggaa
     4981 gagaataatc tgcacgaaga gaaagacgag gagcgcaaat gaaacgacgt gacaccatcg
     5041 tgcgctacac cgcgccggaa cgtatcaacc actggatcac cgccttctgc ttcatcctgg
     5101 cggcggtgag cgggctgggc tttttgttcc cgtccttcaa ctggttgatg caaatcatgg
     5161 gcacaccgca gctggcgcga attctgcacc cgtttgtcgg cgtggttatg tttgcctcgt
     5221 tcatcatcat gtttttccgt tactggcatc acaacctaat caatcgggat gatatctttt
     5281 gggcgaagaa tattcgtaag atcgtcgtca acgaggaagt aggtgacacc gggcgttata
     5341 acttcggtca gaaatgcgtt ttctgggcgg cgattatttt cctggttctg ctgctggtga
     5401 gcggcgtgat tatctggcgt ccttattttg cgcctgcttt ctcaatcccg gtgatccgat
     5461 tcgcgttaat gctgcattca tttgccgcag tggcgttaat tgtggttatc atggtgcata
     5521 tctacgccgc cctttgggtg aaaggcacga ttaccgccat ggtggaagga tgggttacca
     5581 gcgcctgggc gaagaaacat cacccgcgct ggtaccgtga ggtccgcaag acaacggaaa
     5641 agaaagctga atgagtattc gcataatccc gcaagatgag ctgggttcaa gcgagaaacg
     5701 tacggcggat atgattccgc cgttattgtt ccctcggctc aagaatttat acaaccgccg
     5761 cgccgagcgt ctgcgcgagc tggcagaaaa taatcctctg ggtgattacc tgcgctttgc
     5821 tgcgcttatc gcccacgccc aggaagtggt gctgtacgac catccgctgg agatggatct
     5881 gactgcgcgc attaaagaag ccagcgcaca aggcaagccc ccgctggata ttcacgttct
     5941 gccgcgtgat aagcactggc aaaagctgct gatggcgctg attgctgagc tgaaacctga
     6001 aatgagcggc ccggcgctgg cagtgattga gaatctggag aaggcatcga ctcaggagct
     6061 ggaagatatg gccagcgcgc tgtttgcctc tgatttctcg tccgtcagca gcgataaagc
     6121 gccgtttatc tgggctgcac tgtcgctcta ctgggcgcag atggccaatc tgatccccgg
     6181 caaagcccgc gctgaatacg gcgagcaacg tcaatattgc ccggtttgtg gttctatgcc
     6241 ggtgtccagc atggtgcaaa ttggcaccac tcaggggcta cgttacctgc actgcaacct
     6301 gtgtgaaact gaatggcacg tagtgcgcgt aaaatgcagc aactgcgagc agagcggcaa
     6361 actgcattac tggtcgctgg atgacgaaca ggccgcgatt aaagccgaaa gctgcgatga
     6421 ctgcgacact tacctgaaaa ttctctatca ggaaaaagat ccaaaaatcg aagccgtagc
     6481 agatgacctc gcctctctgg tactggacgc acgaatggag caagaaggct atgcccgcag
     6541 ttccatcaac ccgttcctgt ttccgggtga aggagagtaa tctctgacgt tttccgggtg
     6601 gcgcaggtcg cccggattac agctcatagg gtgtgacgac accatctctc gtattccgcg
     6661 ttaccacctc aagctatgcc gccagtgccg gtttggcctc aatttaccca ccaccacatc
     6721 aataaggtta tgggcatgag actgatgaca agcgtaagat tgcctgatgc gctgcgctta
     6781 tcaggcctac caataaactg caatacattg aatttatacg actttgtagg ccggataagg
     6841 cgttcacgcc gcatccggca tgaacaacgc gcacgttgtc agcaatctga ttgacatcat
     6901 tttttcccat taccattcct cgcgcagctt acgctgatat tcgacaccat cttcctcaca
     6961 cccttgccag atgccaggaa cactggttct tgctgtttgc gattgattta tcaggtattg
     7021 atctaccgct tcccttaata ggtccgcacg aggaagatta cgctgcacct cgagatcatc
     7081 aagttgctta atcacctcat tcgataaatc gagtaaaatt ctgcccatat ctatacctgc
     7141 cagagagttc ataaatatct cgccaatatc atttttgaat ctatggagag aaaagtaccc
     7201 ttgccgaatc tttaaagaaa gctcatttac gcatcatttt ttatttttgc gaggcgtttt
     7261 ccagatatga tgtaacagtt gcagttatta taagttcaag taaaacagcc ttgtattaat
     7321 accagaataa gggcatctgt tttttatatt caagaatgaa aaatttttgt cattccttat
     7381 gctccttaca ctgatcatca acaccaacta cctccccctt ttgcctgcct ccctttgctt
     7441 tacgcaccgg gaattgctga cgttccagat attgctctac cgcttcgcgt aaaattgcag
     7501 atcgtgaaac cttacgccag ccccgaagct tgttcagccg tttaattgcc tcttctgata
     7561 aatgaagaaa aaccgtattc atcgccatta ccaatacctt acatatatta ctcattaatg
     7621 tatgtgcgaa aattacgccg gaaaatcatt taaaaaaagc ggatttttgc atgttgtttt
     7681 gtttttgcga ggcgttttcc agaaataata agagtgttgc agttgtttca tttattactc
     7741 aaaaatggtt tagttatcgc ccagggtgaa ttatgggtgc tatgaatata ttatattcag
     7801 agatatttat ttgcataatc tgaatggtgt agccgaaaaa cgtcagcatc ctaacagcac
     7861 caggatttaa ggtgaaatta atctttcatc acagaccggt cagtactgcc accaaccggt
     7921 ctttacttgc tcatcgttat aattttgttg gtaacagttc gggaaagttg tttttctaaa
     7981 ttaacaacag aataactttc ttgtttaatg agattaatat tggcaaccat tatagcctcc
     8041 ttcccacggt ttaagagcaa acatacaaca taattattca taacatacag agcagtaaat
     8101 gaatgatact gacaatgatg ctagtccatt atctttgcat aatatttgtt agctatagat
     8161 tttaaaaata tttatgagaa aagtatggca ccagaggggg ttttgactat caaaaatcgc
     8221 tcaaacatga actaagatga tgaattaagc attatctgcg ataattgcca ctcagttcta
     8281 caaataatat ttaaatgctc ctgaacagtg atgtagcaag acacgtatgg agccaacgaa
     8341 gaataaaaat ttatagagtt cttatttaat ataaccgaaa tagccaagga ctaatataaa
     8401 tgacctgaat gagagaggca gcaccgcccc tctccatcag ctactcttct tcgttcccgc
     8461 cctcttcata cgggccaaat ggcttcgcgg gcagaacgat atacgtgcct tcaaacactg
     8521 cacccggcgt ctcgtcgcca aagatttcga cctgcatctg cacccgtgct tttcgtccgc
     8581 gcgccagacg gtcgagatcg ccgcttaagg caccgaggtc ggctaccgca tgaggtttac
     8641 cgctaatcgg cttgctgtag cggatatgcg catccgcaag aataatcgtt ccgccgaggt
     8701 ggcgttcacg cagcatcagc cagataagtc cccaaccggt gagcgtcgcc agtgagaata
     8761 aactcccggc aaacagcgta tggtgcggat tctgattgcc ggtttctggc atggtagtga
     8821 taaatttttg cccggtatat tgctgaatgc gcacgcccat tttttcacta agcgggatat
     8881 gttcgtacca cgcctgttgc agctgcgcgc accagtcgcc gcgatgcaga atgtcatcca
     8941 gagtggcgac gggcttaatc atcaaaaaat ggcgaatcgg cgtggtggtt ggcgtggtga
     9001 tttctccctg attaacaaac cccagcttgg cgaaaaactc caccgcgtct tcacgggcgc
     9061 tacaggtcac gcgcttaacg ccttcctgac gcgccaccga ctccagggtc atcgccatca
     9121 gcgtgcctaa ccctttgtcc tgcacgtcgg gatgaacggc cataaagcga atggacgctt
     9181 cattgtcggc attaatatac agtcggccta ccgccaccag attaccctgc tcgtcgacga
     9241 ccatctggtg atgcgccatc gcatcccacg cgtcgcgttc cgaacctttt ggttgatgca
     9301 ggggcttacg caacatttcc cagcgaaact gatagtaacg ctctaattct tcttctgttt
     9361 gtggaacccg aaggtgatac atagcgatac tctctcttgt ttcccgtgac aaccctggaa
     9421 gctggctcat acctgcaacc agaatgtcac ggggccatca ttgaccagcg atacctgcat
     9481 atccgcagcg aagcgtcctg tttgcgtgtt catctcttgc tgacggcagc gttcgacgaa
     9541 atagtcatat aacgcctctg cgcgatccgg tgatgcacct ttggagaaac ttgggcgcat
     9601 cccccgttcg gtatctgcgg cgagggtaaa ctgggaaacc accagcacac tgccgcccgc
     9661 ctgttgcacg ttgagattca tcttgccttc ggcatcgcta aagatgcggt agccgagcac
     9721 acgctcgcac agacggtttg ctttctgttc gtcgtcatcc ttttcgacac ccaataacac
     9781 caaaagtccc gcgccaattt cgcccgtcac ttctccctcc acggtgacgc tggcacgggt
     9841 tacgcgttga attaatgcaa tcatggttcg tcgtcttctt cttgttcagc tgcttgtttt
     9901 agtttgcggt attccccgag agtgacagta atttccgcgc caagcaagac gatacaccat
     9961 gtccagtaga cccaaacaaa gagaatgggg atcaccgcca gcacaccata aatgagctga
    10021 tatgacggga acatggtgat ataaagcgcg aaacctttct ttcctgcttc gaacaggagt
    10081 gcggcgacaa acgcgccaac aatcgcgtcg cggttaggta cgcggatggt aggaacaatg
    10141 ctgtacagca accagaagga gatccacgac aacagcaacg gaaaaatacg cagcacgttg
    10201 tcgatgacag tattgagatc gctcgcccag cgcagggaga gcaaatagga actgatcgcc
    10261 agactggccc ctgccagcag cggccccagc gttaaaatca tccagtacac ggcgaacgag
    10321 taaatttttg gtcgcgctcg tttactgcgc cagatggtat tcaacgcgct atcgatggag
    10381 tacatcaaca ataacgcggt gacgatcagc ccgcacgccc caacggcggt catcttgttg
    10441 gaattggcaa caaattgttc gatataccgc tgaataacat cgccagtagc aggcagaaag
    10501 ttggcaaaaa taaagtgacg taactgaatg ctgacgtcgg aaaacatggg aaaagcggcg
    10561 aaaagcgcaa aaacaacggc aaccagcggc actaatgaga gcaacgacac ataggcaagg
    10621 ttacctgcca gggttgtcat gttgtcctca tcaatgcgtt gccagagtag ttttagccag
    10681 gcccatagtg gacgggtacg gtgcctggct ttgtcctgaa tggtttttag cataacacct
    10741 tcgcgaaata gtccgggatg gtggttttat ctttcaccag aatactggta atgcccagct
    10801 gattggctcc ttctatatta tcggcgttat cgtcgaaaaa gaccgtatcg ctgggtgaaa
    10861 aaccttccgc ctgcaaaaca tgctggtaaa ttcgtgcttc aggtttgcgc atccccagat
    10921 cttgcgacag atagatatgg tcagcagcat cacgaatttc cgggtattct tccggccaga
    10981 aggtggtatg caggcggttg gtattggaaa gcaccaccac gcgatgcccc tgctcacgca
    11041 gtttatgcat gatggcgatc acttccgggc gcagcgcaac aaacaccgcc tgccagccgt
    11101 gagagaactg ctcgtagctt agcggtagag ccatctcatg acacagcgcc tctgcgaacg
    11161 cttcgtcgct aatttcccca cgctcatgct gatgaaacgc ctcccccata tgaaaactct
    11221 tcttaagcga tgccagcgga atacgcgtta aatcgctcca ggctcccagc acacggttaa
    11281 agtcgatatc gacaatcaca ttacctaaat caaagatata gagcattttt gcctcctttc
    11341 gcgccacaag aaattaactg tagcgggaaa ggatgggttt ggctatgtgg caaggtatga
    11401 agccaggtta acggtcacaa aaatctacgc gtcttcctgg ggaagaatga tttcaatttg
    11461 gctgtcttgt aagcgtgatt ttagcgcagc gggcggcagc tcgtcggtaa agagcgcagt
    11521 gacctgtgcc acgttaccaa tttcaaccgc cgccgaagca tgatacttag tgtgatcggc
    11581 gaccagcaga atatttctcg cgtgcgccat catcgttttc accacgttag cttcgtttac
    11641 atcaaactcc atcaacgcgc catcgctctc aatcgcccca acgcttgtta ccagataatc
    11701 agcacgaaaa tcagccacaa aggacgccgc tgaagggcca atgatcccgc tattatgaga
    11761 gcgcaacgta ccgccgggca ccatcacttc aaagcgcggg ttgtggtaaa gaatatgcgc
    11821 cacacgcagg ctgttggtga ttatccgcaa atgattatgg ttaagtaacg cccgggcaac
    11881 atgctcaaca gtcgtaccaa tggtgataaa tattgttgaa ccatcaggaa tatagtctgc
    11941 caccgcttcg gcaatcgctt ttttttcctc ggtttgcgaa acctcacgct gctcgaacgc
    12001 cgtattaacg acgctggaag cccgacccgc gccaccgtga tggcgcgtaa tcaggccttg
    12061 ctcgcttaat ttacgaatat cccggcggac cgtctgcgtg gagacatcca gcagatttgc
    12121 cagctcatca atattcatat acccacgctc ggcgatcagc atgaggagtt ggtcgtgccg
    12181 cgggttaccg gttagttcgg taaggctcat gaaaattcct cgaaaaacca tcaccctggc
    12241 attttataca aaaagtgaca aaaaagatcg ggtttgatca cagtcaggga tcccggctcg
    12301 tccaccggga cgtgtgcatt ttaacgccgc tacaccgctg gcgaagcgga ctgactccgc
    12361 taaatcccca cttgttgcca gcgccaccgc caaagcgccg tgaaaaacat cacccgcacc
    12421 tgtggtatct accacatcaa ctttgaaggc cggttgatgc tgacgcccac cattttccag
    12481 ccagtcgcag cctgcgctac cctgggtcac atagacatga ccatttgtga gcgtttgtgc
    12541 ctgttttagc gcactggcca tctctttcac gcccgttaag cgcgccagac ccggttctga
    12601 aaaggccgcg tgatcgctta atgccaccag ctcactgata tcctgcggcg taatgtcccc
    12661 gtccagaacg gtcatcacac ccgcctgacg ggccagggtg aaggcttttt tagcgccgtc
    12721 gtgccagcgt acatctgcca gcacaacatc ccactgagag aaatcaattt cctccaacca
    12781 ctctgcgtca ggcagcagat ccgggctggg gtagttaatg attatccgct cgcctttggt
    12841 atccaccatg atggcggatt gcgaagattt cgcctggtta taccgtttgg tgtaacgggt
    12901 gttaacgccc caggattcca gctctgccag caggctgttg cccgtgtcgt catcacctac
    12961 gcgaccaata aaatcgacct gcgcccccag ccttgccgcc gcaaccgctg ccgtcgccgc
    13021 tggcccgcca ccaacttccg tataatttct cgccacgtat ttaccgctct ccgtcggtaa
    13081 cccttccacg taatagatgc gatccatcac ggttatacct acacaagcaa cacgaatcat
    13141 ggtcattcct taaacatttt gggatgcgtt cattttaatt tcaccaattg tttaaaaagt
    13201 gacggctgtc aattttttga cgataaatta caaatacgat caaaaacaga caagcaaagc
    13261 atgtcataaa tgacaaaaag tgacatcact gtattcagga gagggttatg gcagcaatcg
    13321 cgtttatcgg tttaggacaa atgggttcgc caatggcgag caatttattg cagcaagggc
    13381 atcaacttcg cgtctttgat gtgaacgccg aagctgtgcg gcatctggta gacaaaggtg
    13441 cgactcccgc cgccaacccg gcgcaggccg ctaaagatgc cgaatttatc attaccatgt
    13501 tgccgaatgg cgatctggtg cgcaacgtgt tgttcggtga aaacggcgtt tgcgaaggct
    13561 tatctaccga tgcgctggtc attgatatgt ccaccatcca tccgctgcaa accgataaat
    13621 tgattgccga tatgcaagcc aaaggcttca gcatgatgga tgttccggta ggccgtactt
    13681 ctgcaaatgc cattaccggt actctgttac tgctggctgg cggcaccgct gaacaagttg
    13741 aacgtgccac accgatcctg atggcgatgg gcagtgagtt gatcaacgct ggcggtccgg
    13801 gcatggggat ccgcgttaag ctcatcaaca actacatgag catcgcgctc aatgcgcttt
    13861 cggcagaagc cgccgttttg tgcgaagccc tgaatcttcc cttcgatgtt gccgtcaaag
    13921 tgatgagcgg taccgccgcc ggtaaaggtc acttcaccac ttcctggcca aacaaagtcc
    13981 tcagcggaga tctttctccc gccttcatga tcgatcttgc ccataaggat cttggcatcg
    14041 cccttgatgt cgccaaccag ctgcatgtgc caatgccgct gggggccgcc tcacgggagg
    14101 tttatagcca ggcgcgcgca gcgggtcgcg gtcgccagga ctggtccgcc attctggaac
    14161 aggtccgtgt cagtgccggg atgactgcca aagtaaaaat gtaacgactg gataaaggaa
    14221 taaatgaatg aataagtaca ccatcaacga cattacgcgc gcatcgggcg gttttgccat
    14281 gctggcggtc gatcagcgcg aagccatgcg catgatgttt gccgcggctg gggcacccgc
    14341 tccggtagcc gatagcgttt taactgattt caaagttaac gctgcaaagg ccctctcgcc
    14401 ttatgcctcg gcgattctgg tagatcaaca attctgctac cgccaggtgg ttgagcaaaa
    14461 cgcgattgcc aaaagttgcg ccatgattgt cgccgccgat gagttcattc ctggcaacgg
    14521 tattccggtc gatagcgtgg ttattgaccg caaaatcaat ccgctacaga tcaaacaaga
    14581 cggtggcaaa gccttaaaac tgctggtgct gtggcgtagt gatgaagatg cgcagcaacg
    14641 tctggatatg gtgaaagagt tcaacgaact gtgccactca cacggtctgg taagcatcat
    14701 tgagccagtc gtccgcccac cgcgtcgtgg cgataaattc gatcgcgaac aagcgatcat
    14761 cgatgccgcc aaagagctgg gcgacagtgg cgctgacctc tacaaagttg aaatgccgct
    14821 ttatggcaaa ggtccgcaac aagagcttct ctgtgcttca caacgtctga atgaccatat
    14881 caatatgcca tgggtgatcc tctcttccgg tgtcgacgaa aaactgttcc cgcgtgccgt
    14941 acgcgtggca atgacggcgg gcgcatcggg attcctggca ggccgtgcag tctgggcatc
    15001 ggtcgtcggt ttaccagaca acgagctgat gctgcgtgac gtttgcgcac cgaaattaca
    15061 acaacttggc gatatcgtcg acgaaatgat ggctaaacgc cgctaagatg aggataaaag
    15121 gaatgaaatg gtttaacacc ctaagccaca accgttggct ggaacaggaa accgaccgca
    15181 tctttgattt tggtaaaaat tccgtagtgc cgactggttt tggctggtta ggcaataaag
    15241 ggcaaatcaa agaagagatg ggcacccatc tgtggatcac cgctcgtatg ttgcacgttt
    15301 attccgttgc tgcggcgatg ggtcgacctg gcgcttactc gttggttgat cacggtatca
    15361 aagccatgaa cggcgcactg cgtgataaaa aatatggcgg ctggtatgcc tgcgtgaatg
    15421 acgagggcgt ggtggatgcc tccaaacagg gctatcaaca cttctttgct ctgctgggtg
    15481 ccgccagcgc cgtcacaacg ggtcacccgg aagcgcgcaa gctgctcgat tacaccattg
    15541 aaattatcga gaaatatttc tggagcgaag aagagcagat gtgcctggaa tcctgggacg
    15601 aagccttcag caaaaccgaa gagtaccgcg gcggcaatgc caatatgcac gcggtggaag
    15661 ctttcttgat tgtttatgac gtcactcacg acaaaaaatg gctggatcgc gcgattcgcg
    15721 tggcttccgt gattatccac gacgtcgcca gaaataatca ttatcgcgtt aacgaacact
    15781 tcgataccca gtggaatccg ctgccggatt acaacaaaga taacccggcg catcgcttcc
    15841 gcgcgttcgg aggtacacca ggccactgga tcgaatgggg ccgtttaatg ctgcacatcc
    15901 atgctgccct ggaagcccgt tgcgaacaac caccagcatg gctgctagaa gatgccaaag
    15961 gtctatttaa cgccaccgtg cgcgatgcct gggcacccga tggcgcggac gggattgttt
    16021 ataccgttga ctgggaagga aaaccggtgg tccgcgaacg tgtacgttgg cctatcgtcg
    16081 aagcaatggg tacggcctac gcgctctaca ccgtcactgg cgatcgccag tatgaaacct
    16141 ggtatcaaac atggtgggag tactgcatta agtacctgat ggactatgaa aatggttcct
    16201 ggtggcagga gctggatgcg gacaataagg tcaccaccaa agtctgggac ggcaaacagg
    16261 atatttatca cctgctgcat tgcctggtga tcccgcgtat cccgttagcg cccggcatgg
    16321 ctccagcggt tgcagcgggt ctgctggata ttaatgcgaa ataactgatc tgaaaatagg
    16381 gtgcgggttt tcccctctcc ctaaccctct ccccaaaggg gcgaggggac cgtccggtgc
    16441 agtttttggg tttgacatca gcctcacggg aggctgtatg tcgttaatta aggtgccttg
    16501 tatgcaaatc accaatatgc attgcagtgg acagaccgtt tcacttgccg cgggggatta
    16561 tcacgcgacc attgtgaccg tcggtgctgg tctggctgaa ttaacctttc agggttgtca
    16621 tttagtcatc ccgcacaaac ccgaagagat gccgctggcg catctgggta aagtgcttat
    16681 tccgtggccg aaccggatcg ccaacggctg ttaccgctat caggggcagg aatatcagtt
    16741 acccattaat gaacatagtt caaaagccgc tattcacggg ctgcttgcct ggcgagactg
    16801 gcaaattagt gaattaaccg ccaccagcgt taccctgaca gcttttctgc cgcccagtta
    16861 cggctatccg tttatgctgg cttcacaagt tgtttattcg ctcaacgcac acacgggtct
    16921 ttccgttgag atcgcaagcc agaatatcgg cactgtcgca gcgccttatg gcgtgggtat
    16981 tcatccttat ttaacctgca acttaacatc tgttgatgaa tatctgttcc agcttccggc
    17041 aaaccaggtt tatgccgtcg atgagcacgc gaatccgaca acgcttcacc acgttgatga
    17101 gctggattta aatttcacgc aggcgaaaaa aatagccgcg acaaaaatcg accacacctt
    17161 taaaaccgct aatgatttgt gggaaatgac cattacccat ccacagcagg cgctttcggt
    17221 aagcctttgt tccgatcaac tctgggtgca ggtttatagc ggtgaaaaat tacagcgtca
    17281 gggactggca gttgaaccta tgagttgccc gcctaacgcc tttaattcag gtatcgactt
    17341 attattactg gaatcaggaa aaccgcaccg cctgtttttt aatatttacg gacagagaaa
    17401 ataacttgta ttgattagca gtcaaaatca ttgaagaaca tttcactcgc taaaggcaac
    17461 attatgtatc ttcaatttat taagttaaaa acagctcagc ttctgtaaag tttttatata
    17521 tcagttttat gagaatcatt ttacataagc ctgtaataac aggaaggcaa caatctcgtt
    17581 ctcaactcta tggagattag ttatggatac gtcacgtcca cagttattag attttcaatt
    17641 tcatcagaat aacgacagtt ttaccctaca ttttcaacaa cgtcttattt taacccatag
    17701 caaagataat ccttgtttat ggattggctc aggtatagcg gatatcgata tgttccgcgg
    17761 taatttcagc attaaagata aactacagga gaaaattgcg cttaccgacg ccatcgtcag
    17821 ccagtcaccg gatggttggt taattcattt cagccgtggt tctgacatta gcgccacgct
    17881 gaatatctct gccgacgatc aggggcgttt attgctggaa ctacaaaacg acaaccttaa
    17941 ccacaaccgt atctggctgc gccttgccgc tcaaccagag gaccatatct acggctgcgg
    18001 cgaacagttt tcctacttcg atctgcgtgg caaaccgttc ccgctatgga ccagtgaaca
    18061 aggcgttggt cgcaacaaac aaacctatgt cacctggcag gccgactgca aagaaaatgc
    18121 gggcggcgac tattactgga ctttcttccc acagcctacg tttgtcagca cgcagaagta
    18181 ttactgccat gttgataaca gttgctatat gaacttcgac tttagtgccc cggaatacca
    18241 tgaactggcg ctgtgggaag acaaagcaac gctgcgtttt gaatgtgctg acacatacat
    18301 ttccctgctg gaaaaattaa ccgccctgct gggacgccag ccagaactgc ccgactggat
    18361 ttatgacgga gtaacgctcg gcattcaggg cgggacggaa gtgtgccaga agaaactgga
    18421 caccatgcgt aacgcgggcg tgaaggtcaa cggcatctgg gcgcaggact ggtccggtat
    18481 tcgtatgacc tcttttggca aacgcgtgat gtggaactgg aagtggaaca gcgaaaacta
    18541 cccgcaactg gattcacgca ttaagcagtg gaatcaggag ggcgtgcagt tcctggccta
    18601 tatcaacccg tatgttgcca gcgataaaga tctctgcgaa gaagcggcac aacacggcta
    18661 tctggcaaaa gatgcctctg gcggtgacta tctggtggag tttggcgagt tttacggcgg
    18721 cgttgtcgat ctcactaatc cagaagccta cgcctggttc aaggaagtga tcaaaaagaa
    18781 catgattgaa ctcggctgcg gcggctggat ggctgacttc ggcgagtatc tgcccaccga
    18841 cacgtacctg cataacggcg tcagtgccga aattatgcat aacgcctggc ctgcgctgtg
    18901 ggcgaagtgt aactacgaag cccttgaaga aacgggcaag ctcggcgaga tccttttctt
    18961 tatgcgcgcc ggttctaccg gtagccagaa atactccacc atgatgtggg cgggcgacca
    19021 gaacgtcgac tggagtctcg acgatggcct ggcgtcggtt gtcccggcgg cgctgtcgct
    19081 ggcaatgacc ggacatggcc tgcaccacag cgacattggc ggttacacca ccctgtttga
    19141 gatgaagcgc agcaaagagc tgctgctgcg ctggtgcgat ttcagcgcct tcacgccgat
    19201 gatgcgcacc cacgaaggta accgtcctgg cgacaactgg cagtttgacg gcgacgcaga
    19261 aaccatcgcc catttcgccc gtatgaccac cgtcttcacc accctgaaac cttacctgaa
    19321 agaggccgtc gcgctgaatg cgaagtccgg cctgccggtt atgcgcccgc tgttcctgca
    19381 ttacgaagac gatgcgcaca cttacaccct gaaatatcag tacctgttag gtcgcgacat
    19441 tctggtcgct ccggtgcatg aagaaggccg tagcgactgg acgctctatc tgccggagga
    19501 taactgggtc cacgcctgga cgggtgaagc gttccggggc ggggaagtta ccgttaatgc
    19561 gcccatcggc aagccgccgg tcttttatcg cgccgatagc gaatgggcgg cactgttcgc
    19621 gtcgttaaaa agcatctaat cacatccgcc cgtggggaaa ctcatgggca aagggagaac
    19681 atcgatgagt cacatcacaa cggaagatcc agcaacttta cgcctgccct ttaaagagaa
    19741 actctcttac ggtattggcg acctggcctc taacatcctg ctggatatcg gtacgcttta
    19801 tcttttgaag ttttataccg acgttctggg gctgccaggc acctatggcg gcattatctt
    19861 tttgatttca aaattcttta ctgcgtttac cgatatgggt accggcatta tgttggattc
    19921 ccgacgcaag atcggtccaa aaggtaagtt ccgtcctttt attctgtatg cgtcattccc
    19981 ggtcacctta ctggcgatcg ccaactttgt cggcacaccg tttgatgtca ccggtaaaac
    20041 ggtgatggcc actattctgt ttatgcttta cggactgttt ttcagcatga tgaactgctc
    20101 ctacggcgca atggttcccg ctatcaccaa aaaccccaac gaacgcgcct cactggcggc
    20161 atggcgtcag ggcggcgcta cgctgggcct gctgctgtgc acggtgggat tcgtgccagt
    20221 tatgaatctt atcgaaggta atcagcaact tggctatatc ttcgccgcca cgctgttttc
    20281 actgtttggc ctgctgttta tgtggatctg ctactcgggc gtgaaagagc gttatgtcga
    20341 aacccagcct gctaatccgg cgcaaaagcc gggcctgctg caatctttcc gcgcaattgc
    20401 gggtaaccgc ccgctgttca ttctgtgcat tgccaacctc tgcactttag gggcgtttaa
    20461 cgtcaagctc gccatccagg tctattacac ccagtacgtg cttaacgatc ccatcctgtt
    20521 gtcgtatatg ggatttttca gcatgggctg tattttcatc ggcgtattcc tgatgcctgc
    20581 ctcagtcaga cgttttggca agaagaaagt ttatatcggc ggcctgctga tttgggtgct
    20641 gggcgatctg ctcaactatt tcttcggcgg cggttcggtc agcttcgtgg cgttctcctg
    20701 cctggcgttc tttggctcag cgtttgttaa cagcctgaac tgggcgctgg tttccgacac
    20761 cgtcgagtac ggcgagtggc gcaccggcgt gcgttcggaa ggaacggtct acaccggttt
    20821 taccttcttt cgcaaagtgt ctcaggcgct ggctggtttc ttccccggct ggatgctgac
    20881 gcaaattggc tatgtgccga acgtcgcaca ggctgaccac accattgaag ggttacgcca
    20941 gttgatcttc atctacccaa gcgcactggc ggtagtcacc attgtggcga tgggttgctt
    21001 ctacagcctg aacgagaaga tgtatgtccg cattgtggaa gagatagaag cccgtaaacg
    21061 cacggcgtaa taataataaa cgacgccctg cggggcgtta taaggagtga ttatgtctga
    21121 ccataatcca ctgacattaa aactgaatct gcgggaaaaa atcgcctatg gtatgggcga
    21181 cgtcggttcg aatttaatgc tctgcatcgg tactctgtat ctcctcaaat tttataccga
    21241 tgaattaggg atgcctgctt actatggcgg gattatcttt ctggtggcga agttttttac
    21301 cgcgtttacc gatatgctca ccggattttt actcgactcg cggaaaaata ttgggcctaa
    21361 aggcaaattt cgtcccttta ttttatatgc agcggttccg gcggcgttaa ttgcaacgct
    21421 ccagtttatc gccaccacct tttgtttgcc ggttaaaacg acgattgcca ccgcgctgtt
    21481 tatgatgttt ggactttcat acagtctgat gaactgctcg tatggtgcga tgatcccggc
    21541 aattaccaaa aacccgaatg agcgcgcgca gctcgcggct taccgccagg gtggtgcaac
    21601 catagggcta ttgatttgta ccgtggcgtt tattccgttg cagtcgcttt tttctgactc
    21661 aaccgtcggt tatgcctgtg cggcacttat gttctccatt ggcggcttta tttttatgat
    21721 gctgtgctac agaggcgtca aagagcatta tgtggacaca acgccaaccg gacataaagc
    21781 cagtattctc aaatcatttt gcgcgatatt tcggaatccg ccattgctgg ttttatgcat
    21841 tgctaacttg tgtaccctgg cggcatttaa tatcaaactg gcgattcagg tctattacac
    21901 ccagtatgtg ctgaatgata ttaatttatt gtcgtggatg ggattcttca gtatgggatg
    21961 catcctcatc ggcgtattac tggtgccatt aactgtaaaa tgttttggta aaaaacaggt
    22021 ttatctggct ggcatggtgc tgtgggcggt gggtgatata ctgaattatt tctggggaag
    22081 taactctttc actttcgtca tgttctcttg tgtcgccttt tttggcacgg cctttgtaaa
    22141 cagcctgaac tgggcactgg taccagatac cgtagattac ggtgaatgga aaaccggtat
    22201 tcgtgccgaa ggttctgttt ataccggtta taccttcttt cgtaaaattt ctgccgcact
    22261 tgctggcttc ttgccaggca ttatgctgac gcaaattggt tatgttccca acatcgcgca
    22321 aagcgatgcg acattacagg gtttgcgtca gctcattttt atctggcctt gtgcactggc
    22381 aattattgct gcattgacga tgggattctt ttacacactc aatgaaaaac ggtttgcatt
    22441 gattattgag gaaatcaacc aacgcaaaaa taaagagatg gcgacagaag aaaaaacggc
    22501 ttccgtaacg ttataaatgt caatagccgc tatttccatc ctggtgggtg gcggcctccc
    22561 tacgtttaaa aaatggactt attatgaaaa agattaatgc aataatttta ttatcttctc
    22621 tgacctctgc ctcggtattt gctggcgcat acgtcgaaaa cagggaggca tataatcttg
    22681 cctccgatca gggcgaggtt atgctacgtg tgggttataa cttcgatatg ggcgcgggta
    22741 ttatgttaac caatacctac aactttcagc gagaagatga actaaaacat ggatataacg
    22801 aaattgaagg ctggtatccg ttatttaaac caaccgataa attaaccatc cagcccagtg
    22861 gcttaattaa tgataagagt atcggttcgg gtggtgcagt gtatctggac gtcaactata
    22921 aatttgtacc atggtttaat ctgacagtac gaaatcgcta taaccataat aactatagtt
    22981 caacagattt gagcggggaa ctggataata atgacaccta tgaaattggc acctactgga
    23041 attttaaaat caccgataaa ttttcctata catttgagcc acattacttc atgcgagtga
    23101 atgactttaa tagtagcaac gggaaagatc atcattggga aatcactaac accttccgtt
    23161 accgtattaa tgaacactgg ctcccttatt tcgaattgcg ctggttagac cgcaacgtcg
    23221 aaccgtacca ccgcgagcaa aaccagatcc gtatcgggac gaagtatttc ttctgatgtg
    23281 aaactgccgg atgcggcgta aacgccttat ccggcctacg gttgatacgg ttttcgttgg
    23341 ccggattaag cacatccggc cattaattaa gcttcagccg ccagcatctc tttcttacgt
    23401 tggctaatac gcttaaccag cattacggaa accaccgcac cactgaatgc gaagcaggcc
    23461 ataatgccaa acacgatttt gtagccaata atccccggat ttaaatccag aatgtagcca
    23521 tacagactga agcagaacat cgccggagcg taaccaataa agctacccaa cgccatcgcc
    23581 gcacctgttt tattttcagc aatttttgct tcgccgatag gtgcaaaaaa tacggctcgc
    23641 tgtgtaaaga ctatcgcgcc aaagcccagc gtacatgcca tccctaaata gaccggcata
    23701 ctttcgtgcg gcagcataat caacagtacg agcgcagcgg tactaatgat aaaggtgtag
    23761 catagatatt tacttggcga tttcaggatc ttatctgaaa tcatgccacc aatcggtcca
    23821 ccaatcattt tcagacagta ttggttaatg atgccgtaag cccccaccag cgcaacgggc
    23881 aatagataga tgtttttcag gaatggaatg aagaatgtca ggccacagta aaccgcgtaa
    23941 acgaagaaga cgttaaaagc gataagccag atagttttgt ctttcagcac cgaggtcata
    24001 ctggtgtttt tcgatgctcc gtcttctttt ttcacctcaa cggacggtgc ctcttctttg
    24061 tcattcagga caaagaaaat aataatgcct acggcaatca caataaggga atagaaccag
    24121 atgcctgctt taaaacctaa taagccactg ccaaaccagg taaatactgc caacgcagaa
    24181 aatgccacca cggtatcgac aatgccacgc cctgtttcga agaagccaaa caaccgacct
    24241 tgttgttcgc tattgcccaa tcgacttacc gacttgagca agaccggcca gttcatcatg
    24301 tcgcaagtaa cgccaaatag cgcccagaca aagaggatgc cccaataccc cggcattgtc
    24361 gtcaaataaa cacccagtaa tcctgtcgca atgagtgaga atgacatggt gtatctgcgc
    24421 ggtagtttat cggcaaaata aatagacaga aaaaagccca ctgtggtgac aaatgagttt
    24481 accgacatag cattaccaat ttgaccattg gtcaaatgga aatattcctg catcgggata
    24541 taaaacgcat ctttcagcga cggtaattta taaattgtac cgccacacag tgttaataga
    24601 ctaaataacg cccatttctt tttcgtgagc ataacatccc ctaagcgatt tttaaaatca
    24661 ctgttttaaa ggcaataaga taccgaccat tcatatggaa tggttttatt aactgcgtat
    24721 gagttaaaac ttattagtgg ttcagaagat ggtttgcctc ttgtttgatt tgttgtagta
    24781 cgttacgcac atgatttatc tgattaattg catcttcttt ttctttacgt aaccgcgcat
    24841 ccagtaaatg attttctggc aatggtgttt cactcatctg gcgataaggg atccacggat
    24901 tatcatcttc gtcttcaaag cggaacgccg gcgcatagta atcaacctct tcttccaggc
    24961 catatgccgt cacctgcggc tcatcatcac ccaggcagat aaggtgcgtt aataacgctt
    25021 tgaacggcat atcaccctga cctgaaatac aggctttatg acccaggcca cccggttctt
    25081 taacgatcaa ggcatctttg atatggacct gggtaatatg cggtgccatc gtttttaaag
    25141 cgtcgatggg atgctcattt gcattgatca tgttcgcaaa atcaaacagt aaggaaagag
    25201 attccatctc actttctttg accagcgaca ccagctcatg actttttaaa tcttcatgct
    25261 gctcgatcgt aaaagtcagg ccgctgtcct gatacgtttc ccgtacatag gcaatgtcgt
    25321 tagcgataat cgataatacg tcgcgcaaat taccttcata acgtggataa aaacgtacgg
    25381 acgatgcccc agttttcaac gcgatggcga cggcttcgtc aatagatgcc ttatctgagg
    25441 cgctggtttc aatatgaata tcaaggttca gacggcgggc tttatcccca aaggcagaga
    25501 gttctttatc gtccatatta ccaagagaaa aacgctcgcc atcgagaaca tggattttga
    25561 cgccacgtag attattttca cttgcgatat caagtaaatc agcaggcaac actctttcca
    25621 gccgcatatt taaatgaaag gcataagcat gtaaataaag aggaagagtg tcgacacgtt
    25681 gtagaatctt tcttgcgtta tttattgtca ccataaaaca cctacagatt aatgatgagg
    25741 tctacggcct caaatcgcca atattcaata tctatttgga caatattgcc ttgctggtcg
    25801 gcgcgatgct tttcaattaa gatcgctggc atacccgcag aaccgccaag atacttgctg
    25861 atatcgcccg gcattctgac gggtttgaaa atcaattttt ttactaccgt ctctttttgg
    25921 tagcactttt cccagactgc agaaaatgag tggttttcaa gttgttcaat aaagcccgga
    25981 gcaacttcag gattaatata tgtttcgtga tagaaaactt tatgtccttc cagcgccccc
    26041 cagccggtga tgcgatagag ttcagttgat ggcgtcactg caatcagtgg cgcgagcgtc
    26101 tcgggaatat cgctggtacg gtttttctcg gtaaaccccc aggaaggctc tcgcccttgc
    26161 tcaattgcgg cccgctgaaa gctcgccgac agctccggac tgtaattaaa tcgcggctgg
    26221 gtcacgaacc accccttacg atccttacgg aagattttgg attctgcctc gaggttcaac
    26281 aacgcctggc gcagcgtcat acgtttaatg cccagcagtt ctcccagctc tctttctgaa
    26341 gggagttttc cacccggcgt ggtgatgcca tctttcaacc accgatccag tttctctttt
    26401 gcattttcta cggtggattg attctccgcc attgtttaat ccttttggtt taaaccagat
    26461 gaagcatctt acgcttacgc caaaaaagaa agcaattaac ggcgtatgac tttgcagata
    26521 attgtgacaa agctctctat tgacgtaacc acagacttat aagggagata ctcgcattgg
    26581 tgtgcgctca cgacaggcaa aaaaaaacct gccatcgctg gcaggttttt tatgactaaa
    26641 aaacgaaatt aatcgtcttt cggtgcgcgg ttggcgcggc gacgatcgtt ttccgtcagg
    26701 tgacgtttac gaatacggat agaggtcgga gtcacttcta ccagttcgtc atcatcgatg
    26761 aactccagag cttgttccag agtcatgcgg ataggcggaa ccagaacaac ggcttcgtca
    26821 gtaccggaag cacgcatgtt ggtcagtttc ttaccggtca ggcagtttac agtcaggtcg
    26881 ttagagcggc tatgaatacc gataatctga ccttcgtaaa cttctgcacc gtgaccgagg
    26941 aacagcttac cgcgatcctg cagaccgaac agcgcgaacg cgaccgcttt accctgaccg
    27001 ttagagatca gtacgccgtt ctgacgctga cccacttcac ccggacgtac gtcgtcgtag
    27061 tggctgaagg tggagtacag cagaccagta ccggaagtca tggtcatgaa ctcagaacgg
    27121 aagccaatca gaccacggct tgggatcacg tagtcgagac gtacgcggcc tttaccgtct
    27181 ggattcatgt ttttcaggtc gcctttacgt tcgcccagcg cctgcattac agaaccctga
    27241 tgctgttctt caacgtccag agtcacgttt tcatacggct cttgtttacg accgtcgatt
    27301 tcacggaaga taactttcgg acgggatacc gccagttcga aaccttcacg acgcatgttt
    27361 tcgatcagaa cagacaggtg cagttcgcca cgaccagaaa cgcggaacgc atcggcgtct
    27421 tcggtttctt ctacgcgcag cgcaacgttg tgtaccagtt ctttgttcag acgatccagg
    27481 atctgacgag acgttacgaa cttaccttct ttaccgcaga acggcgaggt gttaacgcag
    27541 aagaacatag aaacggtcgg ctcatcaacg gagagtgccg gcagcgcttc aacgttttgc
    27601 gtgtcgcaaa cggtgtcaga aatgttcagt tcgccaaggc ccgtgatcgc aacgatatcg
    27661 ccagcttccg ccagatcggt ttcgatacgt tccagaccga ggtggcccag cactttaccg
    27721 actttcgcgt tgcgggtttt gccttcgcta tcgatgatag tgacctgctg gttcggcttc
    27781 actttaccgc gcttgatgcg gccaatgccg ataacgccaa catagctgtt gtaatcgagc
    27841 tgagaaatct gcatctggaa cggaccgtca aggtcaacgt ccggcgcagg aacgtggtca
    27901 acaatcgcct ggtacagcgg ggtcatgtct tccgccatat cttcgtggtc cagacccgcg
    27961 ataccgttca gcgcagaagc gtaaacgatc gggaagtcca gctgctcgtc ggtcgcgtcg
    28021 aggttaacga acagatcgaa tacctgatcc acaacccaat caggacgcgc gccagggcgg
    28081 tcaactttgt tgataacaac aatcggcttc aggccgtaag caaacgcttt tttggttacg
    28141 aagcgcgttt gcggcatcgg gccgtcaaat gcgtcaacca ccagcagcac tgagtctacc
    28201 atggacatta cacgttcaac ttcaccaccg aagtcggcgt gccccggggt atcaacgatg
    28261 ttgatacggt aatcattcca tttgatagcg gtgtttttcg cgaggatggt aatcccacgc
    28321 tctttctcca aatcgttgga gtccatcacg cgctcttggg tttcggcacg agagtcgaac
    28381 gtaccggatt gttggagcag cttgtctacc agggtggttt taccatggtc tacgtgcgcg
    28441 atgatggcga tattacgcaa tttttcgatc acaactttgc ctcaggcatt agaaatagcg
    28501 cgttattgta cacggattaa tcgcactaca aaacaggatc acaaacatcc tccgcaaaca
    28561 agtattgcag agtccctttg tgatcgcttt cacggagcat aaaaagggtt atccaaaggt
    28621 cattgcacca acatggtgct taatgtttcc attgaagcac tatattggtg caacattcac
    28681 atcgtggtgc agcccttttg cacgatggtg cgcatgataa cgccttttag gggcaattta
    28741 aaagttggca cagatttcgc tttatctttt ttacggcgac acggccaaaa taattgcaga
    28801 tttcgttacc acgacgacca tgaccaatcc aggagagtta aagtatgtcc gctgaacacg
    28861 tactgacgat gctgaacgag cacgaagtga agtttgttga tttgcgcttc accgatacta
    28921 aaggtaaaga acagcacgtc actatccctg ctcatcaggt gaatgctgaa ttcttcgaag
    28981 aaggcaaaat gtttgacggc tcctcgattg gcggctggaa aggcattaac gagtccgaca
    29041 tggtgctgat gccagacgca tccaccgcag tgattgaccc gttcttcgcc gactccaccc
    29101 tgattatccg ttgcgacatc cttgaacctg gcaccctgca aggctatgac cgtgacccgc
    29161 gctccattgc gaagcgcgcc gaagattacc tgcgttccac tggcattgcc gacaccgtac
    29221 tgttcgggcc agaacctgaa ttcttcctgt tcgatgacat ccgtttcgga tcatctatct
    29281 ccggttccca cgttgctatc gacgatatcg aaggcgcatg gaactcctcc acccaatacg
    29341 aaggtggtaa caaaggtcac cgtccggcag tgaaaggcgg ttacttcccg gttccaccgg
    29401 tagactcggc tcaggatatt cgttctgaaa tgtgtctggt gatggaacag atgggtctgg
    29461 tggttgaagc ccatcaccac gaagtagcga ctgctggtca gaacgaagtg gctacccgct
    29521 tcaataccat gaccaaaaaa gctgacgaaa ttcagatcta caaatatgtt gtgcacaacg
    29581 tagcgcaccg cttcggtaaa accgcgacct ttatgccaaa accgatgttc ggtgataacg
    29641 gctccggtat gcactgccac atgtctctgt ctaaaaacgg cgttaacctg ttcgcaggcg
    29701 acaaatacgc aggtctgtct gagcaggcgc tgtactacat tggcggcgta atcaaacacg
    29761 ctaaagcgat taacgccctg gcaaacccga ccaccaactc ttataagcgt ctggtcccgg
    29821 gctatgaagc accggtaatg ctggcttact ctgcgcgtaa ccgttctgcg tctatccgta
    29881 ttccggtggt ttcttctccg aaagcacgtc gtatcgaagt acgtttcccg gatccggcag
    29941 ctaacccgta cctgtgcttt gctgccctgc tgatggccgg tcttgatggt atcaagaaca
    30001 agatccatcc gggcgaagcc atggacaaaa acctgtatga cctgccgcca gaagaagcga
    30061 aagagatccc acaggttgca ggctctctgg aagaagcact gaacgaactg gatctggacc
    30121 gcgagttcct gaaagccggt ggcgtgttca ctgacgaagc aattgatgcg tacatcgctc
    30181 tgcgtcgcga agaagatgac cgcgtgcgta tgactccgca tccggtagag tttgagctgt
    30241 actacagcgt ctaagtgttt tagttgccgt ggaaactttt cgcctgtctc tggcaggcct
    30301 gggatcggtg gcaagcacat cacgccggat gcgacgcaaa tgcgtcttat ccggcctaca
    30361 cggtgatgat gtggtaggcc ggagcaggtg agtcgctctc caacgtgaag tttgtcagct
    30421 atctgtagcc catctctgca tgggcttttt tctccgtcaa ttctctgatg cttcgcgctt
    30481 tttatccgta aaaagctata atgcactaaa atggtgcaac ctgttcagga gactgcttta
    30541 tggcaacagg cacgcagccc gatgctgggc agatcctcaa ctcgctgatt aacagtattt
    30601 tgttaatcga tgacaacctg gcgatccatt acgccaaccc tgccgcgcaa caactgctcg
    30661 cccaaagctc ccgcaaattg tttggtacac cgttaccgga actgttgagc tacttctcat
    30721 taaatatcga gctgatgcaa gaaagtctgg aggcggggca aggttttacc gataacgaag
    30781 tgacgctggt catcgacggg cgctcgcata tcctttctgt gacggcccag cgtatgccgg
    30841 acggcatgat cctgctggag atggctccga tggataacca gcgccgctta agtcaggaac
    30901 agctacagca cgcccagcag gttgctgccc gtgatttagt gcgcggcctg gcacatgaga
    30961 ttaaaaatcc gcttggcggt ttacgtggcg cggcgcagct gctcagcaaa gcgttacctg
    31021 acccatcact actcgaatat accaaagtga ttatcgaaca ggcggaccgg ctgcgaaatc
    31081 tggtcgaccg tctgttgggg ccgcagctgc ccggtacgcg cgttaccgaa agtattcaca
    31141 aagtggctga acgcgtggta acgctggtgt cgatggaact gccggacaac gtgcggttga
    31201 ttcgtgatta cgatcccagc ctaccggaac tggcgcacga cccggatcaa attgaacagg
    31261 tcttgctgaa tattgtgcgc aatgcgctac aggcgctggg gccggaaggc ggtgaaatca
    31321 ttctgcgtac ccgcaccgcg tttcaactga ccttacacgg cgagcgctac cggctggcgg
    31381 cgcggattga tgtggaagat aacgggccgg gcattccgcc tcatttgcag gatacgctgt
    31441 tttacccgat ggtcagcggc cgcgaaggtg gcaccgggct tggcttatcc atcgctcgta
    31501 atttgattga tcagcattca ggcaaaattg aatttaccag ttggccaggg cataccgagt
    31561 tctcggttta cctgcctatc aggaaataaa ggtgacgttt atgcaacgag ggatagtctg
    31621 ggtagtcgat gacgatagtt ccatccgttg ggtgcttgaa cgtgcgctcg ctggggcagg
    31681 tttaacctgt acgacgtttg agaacggcgc agaagtgctg gaggcgctgg cgagcaaaac
    31741 gccggatgtg ctgctttcag atatccgtat gccgggaatg gacgggctgg cgctgctcaa
    31801 gcagattaaa cagcgccatc caatgcttcc ggtcatcatt atgaccgcac attccgatct
    31861 ggatgctgcc gtcagcgcct atcaacaagg ggcgtttgat tatctgccca aaccgtttga
    31921 tatcgacgaa gcagtggcgc tggttgagcg cgctatcagt cattaccagg aacagcagca
    31981 gccgcgtaat gttcagctta acggcccaac gaccgatatc atcggcgaag cgccagccat
    32041 gcaggacgtg ttccgtatta tcggtcggct ttcgcgttct tctattagcg tgctgattaa
    32101 cggcgaatcc ggcaccggta aagaactggt cgctcatgcc ctgcatcgcc acagtccgcg
    32161 cgccaaagcg ccgtttatcg cgctgaatat ggcagctatc ccaaaagatt tgatcgaatc
    32221 agaactgttt ggccacgaga aaggcgcgtt tactggcgcg aataccattc gtcaggggcg
    32281 ttttgaacag gccgatggcg gtacattatt cctcgacgaa attggtgata tgccgctgga
    32341 tgtgcagacg cgtttgctgc gcgtgctggc agacggtcag ttttaccgcg ttggcggcta
    32401 tgcgccggtg aaagtggatg tgcggattat cgctgccact caccagaatc tcgaacagcg
    32461 agtgcaggaa ggtaagttcc gtgaggatct gttccaccgc ctgaacgtta tccgcgttca
    32521 tctgccgccg ctgcgcgaac gtcgggaaga tattccccgt ctggcgcgcc attttttaca
    32581 ggttgccgcg cgcgaactgg gcgtagaagc gaagttactg catccggaaa ccgaagctgc
    32641 tctgacgcgt ctggcgtggc caggcaacgt gcgccagctg gaaaacacct gccgctggct
    32701 aacggtgatg gccgccgggc aggaagtgtt gattcaggat ttgcccggcg aactgtttga
    32761 atcaacggtt gcggagagta cttcgcaaat gcaaccggac agctgggcga cgcttcttgc
    32821 gcagtgggca gacagagcgc tgcgttccgg tcatcaaaat ctgctttccg aagcgcagcc
    32881 agagctggag cggacgttac tgacgaccgc gttgcgacat acgcaggggc ataaacagga
    32941 agcggcgcgg ctactcggct ggggccgcaa caccctgacg cgtaagttaa aagagctggg
    33001 gatggagtga ttcacagctt gtgtgtaaag attgattatt gagcgcaaat tgctggtatt
    33061 ttacgcttta ctgttccgat aagttcagta tgatcttgcc cggaaaacgg ggagagtcat
    33121 tatgctggaa tcaataatta atctggtatc gagtggcgca gttgacagcc acacaccgca
    33181 aactgccgtt gctgccgtgc tgtgtgccgc aatgattggg ctgtttagct gaagctcgtt
    33241 gtttatgccg gatgcggaga aagtcgtagg cctgataaga cgcgaccagc gccgcatcag
    33301 gcatcatgct cagatgcctg atgcggcgta aacgccttat ccggcctaca aaagcaataa
    33361 tttcaacagg ttttgttgcc cagcgcatca ggcaatcttg ttctcagcac attgatggcg
    33421 ctttcgtttt ctactttgta aacgaagcgc cattcactat ttaaatcacc cgagagaact
    33481 gctgcatccg cgctttctgg cgcagatagg tatcaaagca catgcaaatg ttgcggatca
    33541 gcaagcgacc tttcgccgtc acctgtattc ccttctcatc cacatccacc agcccatctt
    33601 ttgctaacgg ggcgagcagc ttgagatctt ccgcaaagta atcagcgaag tgcaaatccc
    33661 actgtttctc aataggggcg taatccagac ggaagttgca gatgagcgac ttaatcacat
    33721 cgcggcgaat acagtcatca cgcgttagcg caataccacg ccacagcgca ttgccttgtt
    33781 catccacttg ctgatagtac tgcttcaact ctttctggtt ctgcgcgtag cagtcgccaa
    33841 tcatgctgat ggcggaaacg cccatcccca gcagatcggt atcgccctga gtggtgtagc
    33901 cctggaagtt acgatgcagc acgccttcac gctgggccac cgccagctcg tcatccggac
    33961 gggcaaagtg atccataccg ataaactgat agcccgattg cgtcaggaag gcgatggttt
    34021 cctgcaggat atcgagtttt tgctgcggac tcggcaggtc agcatctttg attttgcgct
    34081 gagcagcaaa aatggtcggc agatgcgcgt agttaaagac actcagacga tcggggttca
    34141 gctccgccac acgtttcagg gtaaaggcga aactctccgg cgtctgtttc ggcaggccgt
    34201 aaatcaggtc gatgttggtg gaggtaaaac caatctcacg cgcatggtta agcagtgcaa
    34261 agatgaactc ttcatcctgc tcgcggttaa ccagacgttg cacttctttg ttgaagtcct
    34321 gcacgcccat gctcaggcga ttaaagcctt cggcgcgtaa atgatcgagt acatccagtt
    34381 cgatttcccg cggatcgact tcgatcgaaa tctccgcatc ggcattgaac tggaagtttt
    34441 cgcgcagcag cttcatcagg cggctgattt gcgctttatt cagatacgtc ggcgttccgc
    34501 cgccccagtg caattggctg acgtgacgcc cggcgaacag cggtgcacga tggacgattt
    34561 cttgctccag cgcgtccaga tactgatcgg ccttgtgctg ctggcgagta acaatcttat
    34621 tgcaaccgca gaagtaacaa agcttatggc agaacgggat atgtacgtag agagataatg
    34681 gacgctcagg atagcgcgcc acggcttgta aaaacgcctg ttcgccgaag tcttctgaaa
    34741 actccagcgc ggtcgggtac gaggtgtatc gtggcccgga atagttatat ttctggatca
    34801 gggccagatc ccagtcgatt tgctgtacag acatgctcac tccttccgat ggcgtctctg
    34861 gcggctacgg cgtaccggcg gatgcccgtt tcgggtcatc agccggttgc gcagccactt
    34921 ttgtcgccgc gacaaccgct gtagtttaac gaataaccac accagataac atataaccgg
    34981 aagggttatc agcagaacgg gaaggcccac ggcggcaatc cgttagttgc cccgcagcag
    35041 acgcatcatg tcttcttgct tctcgtcttc ttcctcttct tcgtcatcgt cataagagag
    35101 gccgagtttc tgcatcaact catcaatacg atccagttta gcatccaccc aggattgctc
    35161 ttcggcactc agggtttcgc ctgcttccag acgttccagc agcgcatcca gacgctcatc
    35221 cgtttccagt aattccaact ccgcctgcgg tgaaagcata ggtttctcac tcttcggttt
    35281 gtgctgtttg gtgacttttt cagtcacgcc caatggaata ggggttttac tgccaatacg
    35341 tggatctttt ggtgcgttct ggcctttgct gcctgacgtg gtgtttccgc ccgctgcgcg
    35401 gctgcccggc gcatgaccac gacgtttttt ctgacgcttg cgatcacgag cttcctgatc
    35461 cagctcctcg cgtgtttttc gacgcgcttt tgcatgacct ttgctgcgtg agtttgaaga
    35521 tgatggtttc ataatggttc gtcttttagc cgttttattc agtatagatt tgcggcggaa
    35581 tctaacagaa agcaagcaaa gaaaaaaggc gacagattac tctgtcgcct tttttcctga
    35641 ctcataaccc ttaacgggtc ttacaatcct tgcaggccgc caacacaccc tgtttttcct
    35701 ttagccggaa caatccgtgt tgattccatt tccgtttaat tacgtctccg gacgtttgtc
    35761 ttcctgacaa tcctctgtct tcgcctcctg gcgctcctga ccctcatcct gagtcattgt
    35821 tcctgttagc gtcctcgctc tatgggtgct actttacgcc tttgctttaa acaaacaatc
    35881 aaccgccatc agtatttgca cattttcaga gttttatata aaagcaattc actgatttat
    35941 atagcttatt tgacatgcat cgcagaattt tctctgctat ttcgcataaa gactatcggc
    36001 aatgtctcac aaagcgtatg gcttttactt acaacgctca cgccgaaaaa tccgcctttt
    36061 attatggttc aggtataatc gccacaaagc tttgactgac ggagacgacc gctttgacta
    36121 atttgaatta tcaacagacg cattttgtga tgagtgcgcc tgatattcgc cacctacctt
    36181 ccgataccgg aattgaagtg gcttttgcag gccgttccaa cgcaggtaaa tccagcgcgc
    36241 tgaacacgct gactaaccag aaaagcctgg ctcgtacctc aaaaacccca gggcgcaccc
    36301 agcttatcaa cctgtttgaa gtggctgacg gcaagcgtct ggttgacttg cctgggtacg
    36361 gttatgcgga agtcccggaa gagatgaagc gcaaatggca gcgtgcgctc ggcgaatacc
    36421 tcgaaaaacg tcagagcctg caaggtctgg tggtgctaat ggatattcgc catccgctga
    36481 aagatttgga tcagcagatg attgagtggg cggtagacag caatatcgcc gttctggtgc
    36541 tgctgaccaa agcggacaaa ctggcaagcg gcgcacgtaa agcgcaattg aatatggtgc
    36601 gtgaagctgt actggcgttt aacggtgatg tgcaggttga aacgttttct tcgttgaaga
    36661 aacaaggcgt ggacaagctg cggcagaaac tggatacctg gtttagcgag atgcagcctg
    36721 tagaagaaac gcaggacggc gaataatttt cttgccttaa tgcttgtgcc ggatgtggcg
    36781 tatccggccc gtaaattcaa tagattacaa ttctaccgtt ggcctgataa acatagcgca
    36841 tcaggcatta cggatctttt ctttcgccca ataaaaaacg ccccagtcat tactgactgg
    36901 ggcggctaaa atattcagcc aaatccgatt acgtgaagta aaaggtctga aagatagaac
    36961 atcttacctc tgtaccctac gcgactaact ttactctttt ttgttcagtt cagaaagcac
    37021 tttttgtaat tttttttcag ttgttgcata ggaatttcta atagccatca caaaacgtga
    37081 cagcttatgt tgcttactta cgaaaaaagg catgttcagg cgaatcttag tgcgcctgat
    37141 cccagttttc gccactcccc acttccacca gcaacggcac atccagacgg gtacagtttt
    37201 ccatcagttg atgaatctgc ttcgcgacgg catcaacatc atctttatga acttcaaata
    37261 ccagttcatc gtgtacctgc atgatcatac gtacacgcgg ttgctcagcc tgtaaccacg
    37321 catcaacggc aatcatcgcc cgtttgataa tgtcggcggc ggttccctgc attggcgcgt
    37381 taatggctgc acgttcagcc gctgcacgac gagcaccatt gctggatttg atatccggca
    37441 gatacagacg gcgtccgtcc agcgtttcaa cgtagccctg ctctttcgcc tgagcacggg
    37501 tgcgttccat atactccagc acgccagggt agcgttcgaa gtaaaggtcc atgtacttct
    37561 gcgcttcttt acgtggaatg ttcaattgcc gcgccagacc gaaagcactc atgccataaa
    37621 tcagaccaaa gttgatcgct ttcgcgctac ggcgttgctc gctggtgacg gtttccagtg
    37681 gcaaaccaaa cacttctgcc gccgttgccc ggtggatatc ttttccttcc gcgaatgcgg
    37741 tcagcaagcc tttgtcacgc gaaagatgcg ccataatgcg cagttcaatc tgcgagtagt
    37801 ccgctgagac aatcacataa tcctctggcg caataaacgc ctggcggata cgacgacctt
    37861 cttcgttacg caccggaatg ttttgcaggt taggatcggt tgacgataaa cgtcccgttg
    37921 cagttactgc ctggtgataa gaggtatgca cacgcccggt tttcgggttg atcatcagcg
    37981 gcagcttgtc ggtgtaggtc gatttcagct tcgccagacc acgatactcc agaatcactt
    38041 ttggcaacgg atagtccagc gccagttctt ccagtacctc ttccgacgtt gacggcgcgc
    38101 cacccggcgt tttcttcagc ggtttaatgc cctgtttttc aaagagaatg gtttgtaact
    38161 gcttggtgga agaaaggtta aattcctcac ctgcaatttc atgcgctttc ttttccagct
    38221 cagccagacg aagggtgagc tcttcagaat gattgtgcag cactttcgga tcgatcttca
    38281 caccgttacg ttcaatgcgt gaaagcaccg gcaccagcgg catttcgata ttctcgaaga
    38341 cgttcaacgg ccctttgtgt ttttgcagat ccggccacat tttcagatgc aactgcaagg
    38401 tgacatctgc atcttcggcg gcgtaacgtc cggcttcttc gagggcaatc tggttaaagg
    38461 tcagttgatt tttgccttta ccagcaatct cttcaaaagt gatggttttg tgcttcaacc
    38521 aacgttccgc gaggctgtcc atatcgtgac gcccggcaac gctattgaga atgtaggact
    38581 ccagcatggt atcaaacgca atcccacgca gttcaatgcc gtagttcgcc agaataccgc
    38641 gatcgtattt caggttttgc ccgaccttca gcgccttttc atcttccagc agcggtttta
    38701 gcaactcgag tgcacgctcg cgagagattt gatcgggcgc atcaagataa tcatgagcaa
    38761 ccggaatata tgccgctacg cctggctcga tagcaaaaga aagcccgacc aggttagcag
    38821 agatgttatc aaggctgtcg gtttcggtat caaatgcaaa taccggcgct ttttccagct
    38881 tcgcaatcca cgctttcagt gtttcttcat caaggatggt gacgtagttg tcataagaaa
    38941 tcaccgttgc cgtcacttct ggtgcttcgt ctgcaacact ggtttcctgt ggcttcgcgg
    39001 ctggttttgc ccctttggcc tgtaaccatt tgcccgcttc gacatcagca gtccagcgtt
    39061 tgaactcata ctttttgaac agccccaaca actcttccgc tgccggttgc tgcacttcca
    39121 gttgttcaca ggtcagctcc agttcaacgt cggttttaat cgtcgccagc tggtatgaga
    39181 gataagcaac ttctttgttt tgctcgagct tcgctgccat tgttttcgcg ccacggaagc
    39241 tcaacccagc aattttttct ggctcggcat acagcgtatc cagtccgcca agaccttgca
    39301 gcaatgcctg cgcggttttt tcaccgacgc ccggtacgcc aggaatgtta tcagaggagt
    39361 cacccatcag cgccaggaaa tcgatgatca gttctggcgg cacgccgtac ttattcacca
    39421 cctcttccgg tccgaggatg gtattcgtca tggtattgat aagcgtaata tttggcgtca
    39481 ccagctgcgc catatcttta tcgccagtgc tgatcagcac cggacgcccg gctttttcgg
    39541 cttcgcgcgc cagagtaccg ataacgtcgt ccgcttctac gccagaaacc gccagcagcg
    39601 gcagtcccat cgctttaacc atcgcgtgca agggttcgat ttgtgcacgc agatcgtccg
    39661 gcattggcgg gcgatgtgat ttgtaatgtt caaacagttc atcacgaaag gtttttccct
    39721 tggcgtcaaa gaccaccgct gcatgcgtcg gtttatattg catgatcaga ctgcgcagca
    39781 tgttgaggac accatacatc gcaccggtcg gctcgcctgc gctgttagtc agcgggggaa
    39841 acgcgtgata tgcgcgataa agataagatg aaccatctac aaggataagt ggattttggg
    39901 ggatctgaac cataatgtcc gtgcctgttt atcagattat gggtaaagga tgccacagac
    39961 aggatgaaaa catgagtttt tcaccgcttt tcgtgaaaat cttttgtaga tcttctggat
    40021 cgctcgcaaa tcgtcatgtg gataactttg tgcataaatt atttacatcg cttttaattt
    40081 attatcatgc tttttacagc atgatgtttg tctttgtttt tcatgcagtt aaaaataaat
    40141 ccatccctaa taattgagat aatgggattt tttctaatgt ggatagatat gaattatttt
    40201 tctccttaag gatcatccgt tatttgggtc gttttctgct aaaatctgcg ccttgcgctt
    40261 ctttagcgca ctgtctatgg ctaacctttt gaataaattc attatgacga gaatactcgc
    40321 tgcgataacc cttttgctga gtatcgtatt gaccattttg gtcactattt tttgttccgt
    40381 cccgatcatc attgccggga ttgtaaaact attgctacct gtgccagtca tttggcgaaa
    40441 ggtttcgcgt ttttgtgatt ttatgatgta ttgctggtgt gaaggtctgg cggtattact
    40501 gcatctgaac ccacaccttc aatgggaagt tcacgggctg gaagggttaa gtaagaagaa
    40561 ctggtatctg cttatttgta accaccgtag ttgggcagat attgtcgtac tgtgcgtgct
    40621 gtttcgtaag cacattccga tgaataaata tttcctcaag caacagctgg cctgggtgcc
    40681 atttcttggc ctggcgtgct ggtcgctgga tatgccgttt atgaagcgtt attcccgcgc
    40741 ttatttatta cgtcatccgg agcgacgtgg taaagatgtt gaaaccactc ggcgttcttg
    40801 tgaaaagttt cgcctgcatc ccaccaccat tgtcaatttc gttgaaggct cccgtttcac
    40861 gcaagaaaaa catcagcaaa cccactccac ttttcaaaac ttgttgccac caaaggcggc
    40921 aggcattgcg atggcgctaa atgtactggg taaacaattc gataaactgc ttaatgttac
    40981 gctgtgttat ccggacaata accgtcagcc gttcttcgat atgttaagcg gtaaactgac
    41041 gcggattgtc gtacatgtgg atttacagcc tattgccgat gagttacatg gcgactacat
    41101 caatgacaaa agctttaagc gccattttca gcaatggctg aactcattgt ggcaggaaaa
    41161 agaccggctt ctgacgtctc tcatgtcatc acagcgtcag aataagtaag ttttactcgc
    41221 ctctgaatga gcagaggcga gtgagtattt taatgaacaa aacgtccggc acgagacata
    41281 aattcttctt cgctcatctc ctgtccgtta aaaacaactt tacccggtgt ataacgcagc
    41341 tgcagcgagg cggtattgtt gtcaatcgtg attaactgaa acatctgacc taatgtcatc
    41401 atcccgctga tttgtttatc agcctgcttt tgcgcttttt ccgcatccat tccttcagat
    41461 aaattaagct gttttgcggt ttctgtgacg acattaagcg gtaacttcac atcaaaattg
    41521 agcgatttga tatctttgtt tgtggatgat gaagatttgg ctgggtcggc aatactgata
    41581 tccagattgg catttagttc gccgagtgcg ttcttccatc ttaccggttg tttaatggtc
    41641 ggctcacttt tttgtaataa cggtaaatac tctttgaaca atgcagcatt cacttcttgc
    41701 agagcaactt catcgtttgc taactcaggg tgtgcagcaa gctgcttctg catcgcaatg
    41761 ttatactgga tgataaattg gcgcactgct gagggatcaa tagattcagc aatcaatgac
    41821 cactcaccac taccgagttg ctgattccct tttgttaact tatcaagttc gtaggtgaga
    41881 ttgacattga tataatcttt gtctttaacg cgatccagcc tggtttttgc aacgaaagca
    41941 tcgatttggg caacgtcttc cccgtgattg ataatgttaa tctgattaaa tttcgactcg
    42001 ctttcaccaa ccggaaattt cttttcttct aatcgcgcca gagaatcaat ggtaaaactt
    42061 tttgccgtta ctttgttcat tggtgataat tgcagaacaa tatcttcgac tttgccttca
    42121 atatccaggt tagacaatga actaccatca ccattaaaag taaactggcc ctcaccaaaa
    42181 gaaaactttc catactctgc aggggcaaca tctaatgtcg tagagaatga gccaccaaac
    42241 gcgaatcgca atgtcgcttc cacgggcgat ttatttttcg cggcgataaa tagcggttgt
    42301 gtcagttcat tattcactaa gttcactttt gccgctgcca gtgctgggat gacattacca
    42361 tgcattaaca ttgtgatggg caacggaccg tgctcaacat ccacatcaaa tacaactttc
    42421 tggcctggct tgatattgag atcgggtgca ccgttatcga atgtcatttg catttgaaaa
    42481 cgggaattaa aaaagccttt gtcaaaattt tgataactta acgtcatatc gtaggcatgt
    42541 tcacctttct ttttagcatc gttaaaatct ttaataaatt tttcgacacc aggctgaatt
    42601 tgcgtacctg tgtaccatgt gccaccaccc cagattacgg ctaacgcaac aataacacct
    42661 gtagctgact tacgtatcat ataaatattc cctgataaaa cagcaaaact ttgaatatcc
    42721 acttatgctg aaataatgtc cagcggcagg atgcattatc agaatgtatt tatatt
//
LOCUS       DACAOP010000031        42002 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.031, whole genome shotgun sequence.
ACCESSION   DACAOP010000031 DACAOP010000000
VERSION     DACAOP010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42002
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.031"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(430..2844)
                     /locus_tag="IT892_001869"
     CDS             complement(430..2844)
                     /locus_tag="IT892_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3135093.1"
                     /translation="MIARWFWREWRSPSLLIVWLALSLAVACVLALGNISDRMEKGLS
                     QQSREFMAGDRALRSSREVPQAWLEEAQKRGLKVGKQLTFATMTFAGDTPQLANVKAV
                     DDIYPMYGDLQTNPPGLKPQAGSVLLAPRLMALLNLKTGDTIDVGDATLRIAGEVIQE
                     PDSGFNPFQMAPRLMMNLADVDKTGAVQPGSRVTWRYKFGGNENQLDGYEKWLLPQLK
                     PEQRWYGLEQDEGALGRSMERSQQFLLLSALLTLLLAVAAVAVAMNHYCRSCYDLVAI
                     LKTLGAGRAQLRKLIVGQWLMVLTLSAVTGGAIGLLFENVLMVLLKPVLPAALPPASL
                     WPWLWALGTMTVISLLVGLRPYRLLLATQPLRVLRNDVVANVWPLKFYLPIVSVVVVL
                     LLAGLMGGSMLLWAVLAGAVVLALLCGVLGWMLLNVLRRMTLKSLPLRLAVSRLLRQP
                     WSTLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIATEQVAPLKAF
                     LAEHQIVPESFYPVVRARLTAINDKPTEGNEDEALNRELNLTWQNTRPDHNPIVAGNW
                     PPKADEVSMEEGLAKRLNVALGDTVTFMGDTQEFRAKVTSLRKVDWESLRPNFYFIFP
                     EGALDGQPQSWLTSFRWENGNGMLTQLNRQFPTISLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTACGMLLLLAQVQVGMRQRHQELVVWRTLGAGKKLLRTTLWCEFAMLGFVSG
                     LVAAIGAETALAVLQAKVFDFPWEPDWRLWIVLPCSGALLLSLFGGWLGARLVKGKAL
                     FRQFAG"
     gene            complement(2841..3527)
                     /locus_tag="IT892_001870"
     CDS             complement(2841..3527)
                     /locus_tag="IT892_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP3135094.1"
                     /translation="MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALVGE
                     SGSGKSTLLAILAGLDDGSSGEVSLVGQPLHNMDEEARAKLRAKHVGFVFQSFMLIPT
                     LNALENVELPALLRGESSAESRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLIMVTHDLQLAARCDRCLR
                     LVNGQLQEEA"
     gene            3498..4121
                     /gene="tesA"
                     /locus_tag="IT892_001871"
     CDS             3498..4121
                     /gene="tesA"
                     /locus_tag="IT892_001871"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.2.14"
                     /EC_number="3.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional acyl-CoA thioesterase I/protease
                     I/lysophospholipase L1"
                     /protein_id="HAP3135095.1"
                     /translation="MNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSA
                     SAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLR
                     GFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVP
                     LLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS"
     gene            4111..4920
                     /gene="ybbO"
                     /locus_tag="IT892_001872"
     CDS             4111..4920
                     /gene="ybbO"
                     /locus_tag="IT892_001872"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HAP3135096.1"
                     /translation="MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLA
                     GCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGP
                     LSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA
                     ASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARF
                     TLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMVLKRLLPGRVMDKILQG"
     gene            4981..5835
                     /gene="cnoX"
                     /locus_tag="IT892_001873"
     CDS             4981..5835
                     /gene="cnoX"
                     /locus_tag="IT892_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415025.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperedoxin"
                     /protein_id="HAP3135097.1"
                     /translation="MSVENIVNINESNLQQVLEQSMTTPVLFYFWSERSQHCLQLTPI
                     LESLAAQYNGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQESNYTDALPLLKDAWQLSNQNGEIGLLLAETLIA
                     LNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVAENPEDAAL
                     ATQLALQLHQVGRNEEALELLFGHLRKDLTAADGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     gene            complement(5898..6677)
                     /gene="fetB"
                     /locus_tag="IT892_001874"
     CDS             complement(5898..6677)
                     /gene="fetB"
                     /locus_tag="IT892_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HAP3135098.1"
                     /translation="MNSHNITNESLALALMLVVVAILISHKEKLALEKDILWSVGRAI
                     IQLIIVGYVLKYIFSVDDASLTLLMVLFICFNAAWNAQKRSKYIAKAFISSFIAITVG
                     AGITLAVLILSGSIEFIPMQVIPIAGMIAGNAMVAVGLCYNNLGQRVISEQQQIQEKL
                     SLGATPKQASAILIRDSIRAALIPTVDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVTQLKKK"
     gene            complement(6664..7341)
                     /gene="fetA"
                     /locus_tag="IT892_001875"
     CDS             complement(6664..7341)
                     /gene="fetA"
                     /locus_tag="IT892_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein FetA"
                     /protein_id="HAP3135099.1"
                     /translation="MQENSPLLQLQNVGYLAGDAKILNNINFSLRAGEFKLITGPSGC
                     GKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYRQQVSYCAQTPTLFGDTVYDNLI
                     FPWQIRNRQPDPAIFLDFLERFALPDSILTKNIAELSGGEKQRISLIRNLQFMPKVLL
                     LDEITSALDESNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQ
                     EARYELA"
     gene            7487..8404
                     /locus_tag="IT892_001876"
     CDS             7487..8404
                     /locus_tag="IT892_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HAP3135100.1"
                     /translation="MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPG
                     LSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVS
                     NLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
                     DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSA
                     FLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVM
                     MPLEASSLMGSIAGIAELVKDSANKRTQP"
     gene            8401..8859
                     /locus_tag="IT892_001877"
     CDS             8401..8859
                     /locus_tag="IT892_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415021.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HAP3135101.1"
                     /translation="MMELMVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     VVWLVPLGWEWQGVMFAILTLLAAWLWWKWLSRRVREQKHSDSHLNQRGQQLIGRRFV
                     LESPLVNGRGHMRVGDSSWPVSASEDLGAGTHVEVIAIEGITLHIRAVSS"
     gene            complement(8860..9267)
                     /locus_tag="IT892_001878"
     CDS             complement(8860..9267)
                     /locus_tag="IT892_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CueR"
                     /protein_id="HAP3135102.1"
                     /translation="MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHL
                     NELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMR
                     DQLLALANACPGDDSADCPIIENLSGCCHHRAG"
     gene            complement(9392..10684)
                     /locus_tag="IT892_001879"
     CDS             complement(9392..10684)
                     /locus_tag="IT892_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP3135103.1"
                     /translation="MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEA
                     STWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTL
                     AVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
                     VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADK
                     VKDPQVIMPRAFLVAIGVTTLLYISLALVLLSDVSALELEKYADTAVAQAASPLLGHV
                     GYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKSLWRQSTWGNIIVVV
                     LIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVI
                     VGFIYSLWSQGSRALIWIIGSLLLSLIVAMVMKRNKTV"
     gene            complement(10687..11619)
                     /gene="glsA"
                     /locus_tag="IT892_001880"
     CDS             complement(10687..11619)
                     /gene="glsA"
                     /locus_tag="IT892_001880"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAP3135104.1"
                     /translation="MLDANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPGQLAAVA
                     IVTCDGNVYSAGDSDYRFALESISKVCTLALALEDVGPQAVQDKIGADPTGLPFNSVI
                     ALELHGGKPLSPLVNAGAIATTSLINAENVEQRWQRILHIQQQLAGEQVALSDEVNQS
                     EQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLLNTIELATLGATLAAGGVN
                     PLTHKRVLQADNVPYILAEMMMEGLYGRSGDWAYRVGLPGKSGVGGGILAVVPGVMGI
                     AAFSPPLDEDGNSVRGQKMVASVAKQLGYNVFKG"
     gene            11881..14385
                     /gene="copA"
                     /locus_tag="IT892_001881"
     CDS             11881..14385
                     /gene="copA"
                     /locus_tag="IT892_001881"
                     /EC_number="7.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-exporting P-type ATPase CopA"
                     /protein_id="HAP3135105.1"
                     /translation="MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVT
                     GTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQ
                     LLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG
                     AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSL
                     WLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQW
                     FPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEK
                     SVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGT
                     VVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALV
                     SAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDA
                     DALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADVDEAQALRLAAALEQGSSHPLAR
                     AILDKAGDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNEQQVGTKAIEAEITA
                     QASQGATPVLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANA
                     IAKEAGIDEVIAGVLPDGKAEAIKHLQSEGRQVAMVGDGINDAPALAQADVGIAMGGG
                     SDVAIETAAITLMRHSLMGVADALAISRATLHNMKQNLLGAFIYNSIGIPVAAGILWP
                     FTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE"
     gene            complement(14600..14941)
                     /locus_tag="IT892_001882"
     CDS             complement(14600..14941)
                     /locus_tag="IT892_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HAP3135106.1"
                     /translation="MKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVSAL
                     INNNRKLTTEMAFRLAKVFDTTVDFWLNLQAAVDLWEVENNMRTQEELGRIETVAEYL
                     ARREERAKKVA"
     gene            15079..15873
                     /locus_tag="IT892_001883"
     CDS             15079..15873
                     /locus_tag="IT892_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135107.1"
                     /translation="MDLLYRVKTLWAALRGNHYTWPAIDITLPGNRHFHLIGSIHMGS
                     HDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPACEALEERISEEQLQNLQHIS
                     QEMGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEG
                     AENQIAMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNDITLPNTFSQ
                     SLYDVLMHQRNLAWRDKLRPMPPGRYVVAVGALHLYGEGNLPQMLR"
     gene            16077..16556
                     /gene="ybaK"
                     /locus_tag="IT892_001884"
     CDS             16077..16556
                     /gene="ybaK"
                     /locus_tag="IT892_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK"
                     /protein_id="HAP3135108.1"
                     /translation="MTPAVKLLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQV
                     YKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGG
                     ISPLGQKKRLPTIIDAPAQEFATIYVSGGKRGLDIELAAGDLAKILDAKFADIARRD"
     gene            complement(16593..18245)
                     /locus_tag="IT892_001885"
     CDS             complement(16593..18245)
                     /locus_tag="IT892_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HAP3135109.1"
                     /translation="MKLLQRGVALALLTTFTLASETALAYEQDKTYKITVLHTNDHHG
                     HFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFR
                     GMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKR
                     QDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHM
                     GHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCK
                     PDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVL
                     YTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAA
                     QMDRTGADFAVMSGGGIRDSIEVGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAV
                     AQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPR
                     LDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ"
     gene            18463..19683
                     /locus_tag="IT892_001886"
     CDS             18463..19683
                     /locus_tag="IT892_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3135110.1"
                     /translation="MAMSEQPQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLS
                     GLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIIN
                     PLPRNKVVLAVSILLILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLL
                     GMLTIFLPDNRHKD"
     gene            19921..21597
                     /locus_tag="IT892_001887"
     CDS             19921..21597
                     /locus_tag="IT892_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kef family K(+) transporter"
                     /protein_id="HAP3135111.1"
                     /translation="MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKAIAIPGAIAQIAVATLL
                     GMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGVAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSLAAFFLVRLFGHSQRTA
                     LTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSR
                     TRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPD
                     IEIIARAHYDDEVAYITERGANQVVMGEREIARTMLELLETPPAGEVVTG"
     gene            complement(21730..23034)
                     /locus_tag="IT892_001888"
     CDS             complement(21730..23034)
                     /locus_tag="IT892_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="HAP3135112.1"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLV
                     DIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQELKQKNLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKK
                     YNVPVVLTLGTKFVIAENPQWWQQFLKDHVSILAMNEDEAEALTGESDPLLASDKALD
                     WVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     gene            23186..24145
                     /gene="aes"
                     /locus_tag="IT892_001889"
     CDS             23186..24145
                     /gene="aes"
                     /locus_tag="IT892_001889"
                     /EC_number="3.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="HAP3135113.1"
                     /translation="MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGTIAEQRQYY
                     TLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDT
                     HDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIG
                     FAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQ
                     QDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLA
                     AHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL"
     gene            complement(24142..25104)
                     /gene="hemH"
                     /locus_tag="IT892_001890"
     CDS             complement(24142..25104)
                     /gene="hemH"
                     /locus_tag="IT892_001890"
                     /EC_number="4.99.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HAP3135114.1"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLL
                     WWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPEMPVALGMSY
                     GSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIR
                     DYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTREL
                     ASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLET
                     LEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR"
     gene            complement(25340..25984)
                     /gene="adk"
                     /locus_tag="IT892_001891"
     CDS             complement(25340..25984)
                     /gene="adk"
                     /locus_tag="IT892_001891"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAP3135115.1"
                     /translation="MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSE
                     LGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIN
                     VDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQ
                     EETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG"
     gene            complement(26165..28039)
                     /gene="htpG"
                     /locus_tag="IT892_001892"
     CDS             complement(26165..28039)
                     /gene="htpG"
                     /locus_tag="IT892_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003903109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HAP3135116.1"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGT
                     KSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEG
                     EYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNV
                     SREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFAN
                     QEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELL
                     RKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKAL
                     TPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKY
                     IFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
                     "
     gene            complement(28149..28754)
                     /gene="recR"
                     /locus_tag="IT892_001893"
     CDS             complement(28149..28754)
                     /gene="recR"
                     /locus_tag="IT892_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAP3135117.1"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAEL
                     CAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF"
     gene            complement(28754..29083)
                     /locus_tag="IT892_001894"
     CDS             complement(28754..29083)
                     /locus_tag="IT892_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAP3135118.1"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     gene            complement(29136..31067)
                     /gene="dnaX"
                     /locus_tag="IT892_001895"
     CDS             complement(29136..31067)
                     /gene="dnaX"
                     /locus_tag="IT892_001895"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAP3135119.1"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAL
                     SLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGI
                     EWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLI
                     GRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQ
                     PQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERL
                     ASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPE
                     LAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNR
                     GAQQKLAEALSMLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNI
                     QTLRRFFDAELDEESIRPI"
     gene            complement(31196..31747)
                     /gene="apt"
                     /locus_tag="IT892_001896"
     CDS             complement(31196..31747)
                     /gene="apt"
                     /locus_tag="IT892_001896"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAP3135120.1"
                     /translation="MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDL
                     EYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFD
                     LGGEQRLEKQGITSYSLVPFPGH"
     gene            complement(31900..32277)
                     /locus_tag="IT892_001897"
     CDS             complement(31900..32277)
                     /locus_tag="IT892_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF454 family protein"
                     /protein_id="HAP3135121.1"
                     /translation="MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGSYLRFWQKHHAMPRGVKPRAILLILLTFAISLWFVQMPWVRIMLL
                     VILACLLFYMWRIPVIDEKQEKH"
     gene            32347..32874
                     /gene="priC"
                     /locus_tag="IT892_001898"
     CDS             32347..32874
                     /gene="priC"
                     /locus_tag="IT892_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N''"
                     /protein_id="HAP3135122.1"
                     /translation="MKTALLLEKLEGQLATLRQRCAPVSQFATLSARFDRHLFQTRAT
                     TLQACLDEAGDNLAALRHAVEQQQLPQVAWLAEHLAAQLEAIAREASAWSLREWDSAP
                     PKIARWQRKRIQHQDFERRLREMVAERRARLARVTDLVEQQTLHREVEAYEARLARCR
                     HALEKIENRLARLTR"
     gene            32888..33049
                     /gene="rsmS"
                     /locus_tag="IT892_001899"
     CDS             32888..33049
                     /gene="rsmS"
                     /locus_tag="IT892_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pleiotropic regulatory protein RsmS"
                     /protein_id="HAP3135123.1"
                     /translation="MSLENAPDDVKLAVDLIVLLEENQIPASTVLRALDIVKRDYEKK
                     LTRDDEAEK"
     gene            complement(33261..36623)
                     /gene="mscK"
                     /locus_tag="IT892_001900"
     CDS             complement(33261..36623)
                     /gene="mscK"
                     /locus_tag="IT892_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HAP3135124.1"
                     /translation="MTMFQYYKRSRHFVFSAFIAFVFVLLCQNTAFARASSNGDLPTK
                     ADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRIKEETVQLRQKVAEAPEKM
                     RQATAALTALSDVDNDEETRKILSTLSLRQLETRVAQALDDLQNAQNDLASYNSQLVS
                     LQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQAQQALLNAEIDQQ
                     RKSLEGNTVLQDTLQKQRDYVTANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPD
                     EAARIQANPLVKQELEINQQLSQRLITATENGNQLMQQNIKVKNWLERALQSERNIKE
                     QIAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQSDAF
                     VNKLEEGHTNEVNSEVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLMSV
                     SKNLKSILTQQIFWVNSNRPMDWDWIKAFPQSLKDEFKSMKITVNWQKAWPAVFIAFL
                     AGLPLLLIAGLIHWRLGWLKAYQQKLASAVGSLRNDSQLNTPKAILIDLIRALPVCLI
                     ILAVGLILLTMQLNISELLWSFSKKLAIFWLVFGLCWKVLEKNGVAVRHFGMPEQQTS
                     HWRRQIVRISLALLPIHFWSVVAELSPLHLMDDVLGQAMIFFNLLLIAFLVWPMCRES
                     WRDKESHTMRLVTITVLSIIPIALMVLTATGYFYTTLRLAGRWIETVYLVIIWNLLYQ
                     TVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPPEEPTIALEQVNQQTLRITMLLM
                     FALFGVMFWAIWSDLITVFSYLDSITLWHYNGTEAGAAVVKNVTMGSLLFAIIASMVA
                     WALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYIIIAVGAMTVFGSLGVSWDKLQW
                     LAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGSFSGTVSKIRIRATTIT
                     DFDRKEVIIPNKAFVTERLINWSLTDTTTRLVIRLGVAYGSDLEKVRKVLLKAATEHP
                     RVMHEPMPEVFFTAFGASTLDHELRLYVRELRDRSRTVDELNRTIDQLCRENDINIAF
                     NQLEVHLHNEKGDEVTEVKRDYKGDDPTPAVG"
     gene            complement(36751..37398)
                     /gene="acrR"
                     /locus_tag="IT892_001901"
     CDS             complement(36751..37398)
                     /gene="acrR"
                     /locus_tag="IT892_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrR"
                     /protein_id="HAP3135125.1"
                     /translation="MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVT
                     RGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT
                     EERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT
                     RRAAIIMRGYISGLMENWLFAPQSFDLKKEVRDYVAILLEMYLLCPTLRNPATNE"
     gene            37540..38733
                     /gene="acrA"
                     /locus_tag="IT892_001902"
     CDS             37540..38733
                     /gene="acrA"
                     /locus_tag="IT892_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /protein_id="HAP3135126.1"
                     /translation="MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVT
                     VKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQ
                     ATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAA
                     KAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITL
                     RAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVET
                     RPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAASGAQP
                     EQSKS"
     gene            38756..41905
                     /locus_tag="IT892_001903"
     CDS             38756..41905
                     /locus_tag="IT892_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HAP3135127.1"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYD
                     IIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG
                     KKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALG
                     VSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVG
                     YDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRL
                     RPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKNEDIEHSHTVDHH"
BASE COUNT         9757 a        11168 c        11019 g        10058 t
ORIGIN      
        1 taaagtgccc ttttagttat tgttcatatc cctgtgttag caacaaaaaa aaataaaatg
       61 acacacaaga ccagctaatg tatttatata tttttcacat aaacttattt gttctcaatc
      121 aacaacaact gttattacag gtcactttca atattttatt aaactaacat ttttagcaca
      181 gatgaattca tcatcaacaa attcactata tggataatat ccattcaacg catatgattt
      241 atgattttat tagtctgagt tatttttgta gggctatatt taaaatcaat aaactccacc
      301 gattcagatt aatatcagca atagaaagat aggaaatcac caattcaata acatcatcaa
      361 tgaaacatat tgtagaatta atttaaacaa ggcgttccat tcaaccagaa cgccccttat
      421 ttactctcat caccccgcaa actgcctgaa cagcgcctta cccttaacca gtcgcgcacc
      481 cagccagccg ccgaaaagcg acagcagcag cgctccgctg cacggcagaa caatccacaa
      541 tcgccagtct ggctcccacg gaaaatcaaa cactttcgcc tgcaacactg ccagcgccgt
      601 ttccgcacca attgcggcca ccaggccgga aacaaaccca agcatggcga actcacacca
      661 caacgtggta cgcagcagtt ttttccccgc accgagtgtg cgccacacca ccagctcctg
      721 atgacgctga cgcattccca cctgcacctg tgccagcaac agcaacatac cgcaggcggt
      781 gaccagtacc accatcactt ccagcgcccg acttacctgc tccagcacct gaccgacctg
      841 ttttaaaatc gcgccaatat ctaacaggct aatggtcggg aactggcggt tgagttgtgt
      901 caacatgccg ttgccattct cccagcggaa actggtaagc cagctctgcg gttgcccgtc
      961 taatgcccct tcagggaaaa taaaatagaa attaggccgc agactttccc agtccacttt
     1021 gcgcaggctg gtcactttag cgcggaactc ctgggtatcg cccataaaag tcacggtatc
     1081 accgagggca acgtttaagc gtttcgccag cccctcttcc atcgacactt catcggcttt
     1141 tggcggccag ttaccggcga caatcggatt atgatcgggc cgcgtatttt gccaggtaag
     1201 attgagttcg cggttaagcg cctcatcttc attaccttct gtcggcttat cgttaatcgc
     1261 cgtcagccgc gcccgcacca ccggataaaa cgattccggg actatctgat gttccgcgag
     1321 gaacgctttt agcggtgcta cctgttctgt ggcgatgtta attaaaaagt agttcgggct
     1381 ttctggaggt agctgctgct gccagcggtc gagcagatcg ccacgcaaca ccagcagcag
     1441 tgccagcagc ataaaggaga gcgaaaatgc cgaaagctga cttaacgttg accacggctg
     1501 acgtaacagg cggctaaccg ccaggcgcag aggcagcgat ttcagcgtca tgcggcgaag
     1561 tacattcagc agcatccagc ccagcacacc gcacagcaaa gccagtacta ccgcgcccgc
     1621 cagcaccgcc caaagcagca tgctgccacc cattaatccg gcgagcagca gcacaaccac
     1681 cacactgaca atcggcagat aaaacttcag cggccagacg ttcgctacca catcattacg
     1741 taatacgcgt aaaggctgcg ttgccagcaa caagcgatat ggtcgtagcc ccaccagcag
     1801 cgagatgacc gtcatggtgc caagcgccca cagccacggc cagaggctgg ctggcggtag
     1861 tgcagcaggc agaacgggct tgagcagcac catcaacacg ttttcgaaca acaggcctat
     1921 ggccccaccg gtaacggctg aaagcgtcag caccatcaac cactgaccga cgattagctt
     1981 acgcagttgc gctcgccctg cccccagcgt tttgaggatc gccaccagat cgtagcaact
     2041 gcgacagtaa tgattcatcg ctaccgccac cgctgccact gccagcagca aggtcagaag
     2101 cgccgaaagc agcaggaact gttgcgagcg ttccatcgat cgccccagcg cgccttcgtc
     2161 ctgttccaga ccgtaccagc gttgttcggg tttaagctga ggtaacaacc atttctcata
     2221 gccgtcgagc tggttctcgt tgccgccgaa tttataacgc caggtgaccc gactccccgg
     2281 ctgcacggct ccggttttat cgacatccgc cagattcatc atcagacgcg gagccatctg
     2341 gaaggggtta aaaccggaat ccggttcctg aatcacttct ccggcaatcc gcaaggtggc
     2401 atcgcccacg tcaatggtgt cgcccgtttt caggttaagc agtgccatca ggcgtggggc
     2461 cagcaatacg ctgcccgcct gcggtttcag gccaggggga ttagtttgca gatcgccata
     2521 catcgggtag atatcatcca ccgctttgac gttcgccagc tgcggtgtgt cgcctgcaaa
     2581 ggtcattgtg gcgaaagtca gctgcttgcc gactttcagg ccgcgctttt gcgcttcctc
     2641 cagccacgct tgcggcactt cgcgtgaact gcgcaacgcc cgatcgcccg ccataaactc
     2701 acggctttgc tggcttaagc ccttctccat gcgatcgctg atattgccca gcgccagcac
     2761 gcaggccacc gccaggctta gcgccagcca gacaattaat agcgacggcg aacgccattc
     2821 gcgccagaac caacgtgcaa tcatgcttcc tcctgcaact gcccgttcac cagccgtaag
     2881 cagcggtcgc agcgtgccgc cagttgcagg tcgtgggtca ccataatcaa cgtggtgcca
     2941 tgttcacggt tgagggaaaa cagcaggtcg gcaattttat cgcccgtctg gcggtcaagg
     3001 ttgccggtgg gttcgtcggc aaacagcaca tcaggtcgac cattaaaggc tcgtgccagc
     3061 gccactcgtt gctgttcacc gccggaaagc tgtgccggaa gatgatccag acgtttaccc
     3121 agccctaact gttcgagcaa cgctttcgcc ccgttacgac tttccgcgct actctcaccg
     3181 cgcagcagag ccggaagctc gacgttttcc agcgcgttaa gggtaggaat taacataaat
     3241 gactgaaaaa caaagccgac gtgcttcgcg cgcaactttg cccgcgcttc ttcgtccata
     3301 ttatgtagcg gttgtcccac cagactcact tcgccactgc tgccgtcatc aagcccggcg
     3361 aggatcgcca gcaaggttga cttacccgat cccgactcgc ccaccagtgc gatggtctcg
     3421 ccacgtttga caaccagctc aactccggtg aggatggaga gttcatgctc cccctgaccg
     3481 acggacttct taagatgatg aacttcaaca atgttttccg ctggcatttg cccttcctgt
     3541 tcctggtcct gttaaccttc cgtgccgccg cagcggacac gttattgatt ctgggtgata
     3601 gcctgagcgc cgggtatcga atgtctgcca gcgcggcctg gcctgccttg ttgaatgata
     3661 agtggcagag taaaacgtcg gtagttaatg ccagcatcag cggcgacacc tcgcaacaag
     3721 gactggcgcg ccttccggct ctgctgaaac agcatcagcc gcgttgggtg ctggttgaac
     3781 tgggcggcaa tgacggtttg cgtggttttc agccacagca aaccgagcaa acgctgcgcc
     3841 agattttgca ggatgtcaaa gccgccaacg ctgaaccatt gttaatgcaa atacgtctgc
     3901 ctgcaaacta tggtcgccgt tataatgaag cctttagcgc catttacccc aaactcgcca
     3961 aagagtttga tgttccgctg ctgccctttt ttatggaaga ggtctacctc aagccacaat
     4021 ggatgcagga tgacggtatt catcccaacc gcgacgccca gccgtttatt gccgactgga
     4081 tggcgaagca gttgcagcct ttagtaaatc atgactcata aagcaacgga gatcctgaca
     4141 ggtaaagtta tgcaaaaatc ggtcttaatt accggatgtt ccagtggaat tggcctggaa
     4201 agcgcgctcg aattaaaacg ccagggtttt catgtgctgg caggttgccg gaaaccggat
     4261 gatgttgagc gcatgaacag catgggattt accggcgtgt tgatcgatct ggattcacca
     4321 gaaagtgttg atcgcgcagc cgacgaggtg atcgccctga ccgataattg tctgtatggg
     4381 atctttaaca atgccggatt cggcatgtat ggcccccttt ccaccatcag ccgtgcgcag
     4441 atggaacagc agttttccgc caactttttc ggcgcacacc agctcaccat gcgcctgtta
     4501 cccgcgatgt taccgcacgg tgaagggcgt attgtgatga catcatcggt gatgggatta
     4561 atctccacgc cgggtcgtgg cgcttacgcg gccagtaaat atgcgctgga ggcgtggtca
     4621 gacgcactgc gcatggagct gcgccacagc ggaattaaag tcagcctgat cgaacccggt
     4681 cccattcgta ctcgcttcac cgacaacgtc aaccagacgc aaagtgataa accagtcgaa
     4741 aatcccggca tcgccgcccg ctttacgttg ggaccggaag cggtggtgga caaagtacgc
     4801 catgctttta ttagcgagaa gccgaagatg cgctatccgg tgacgctggt gacctgggcg
     4861 gtaatggtgc ttaagcgcct gctgccgggg cgcgtgatgg acaaaatatt gcaggggtga
     4921 gttgaagcgc gcgcttaagc ccccatgtca aagaaaatat cgacaacaga gagcgactcc
     4981 atgtccgtag aaaatattgt caacattaac gaatctaacc tgcaacaggt tcttgaacag
     5041 tcgatgacca ctccggtgct gttctatttt tggtctgaac gtagccagca ctgtttgcag
     5101 ttaaccccaa ttctggaaag cctcgcggcg cagtacaacg ggcaatttat tctggcgaag
     5161 ctggactgcg acgcggagca gatgattgcc gcgcagtttg gtctgcgtgc gattccgacc
     5221 gtgtatctgt tccagaacgg gcaaccggta gatggcttcc aggggccgca accggaagag
     5281 gcgatccgcg ccctgctgga taaagtgctg ccgcgcgaag aagagctgaa agcgcagcag
     5341 gcgatgcaac tgatgcagga aagcaattac accgatgccc tgccattgct gaaagacgcc
     5401 tggcagttgt cgaatcagaa cggggagatc ggcctgctgc tggcagaaac gctgattgcg
     5461 ctgaaccgtt ctgaagatgc ggaagcggtg ctgaaaacca ttccgttgca ggatcaggac
     5521 acccgctacc aggggctggt ggcgcaaatc gaactgctga agcaggcggc tgatacgccg
     5581 gaaattcaac agttgcaaca gcaggtggcg gagaatccag aagatgccgc actggcgacg
     5641 caactggcgc tgcaactgca tcaggttggg cgcaatgaag aggcgctgga gttgctgttc
     5701 gggcatctgc gtaaagatct caccgccgca gacggtcaga cgcgtaaaac gttccaggag
     5761 atcctcgctg cgctgggtac gggtgatgca ctggcgtcga agtatcgccg ccagctgtat
     5821 gcattgttgt attgatattc cgttgatcgg cacatgaacc acaacgccgg atgcgatgct
     5881 gcgcatccgg catcgcatca tttcttcttc aattgcgtca ccaccaactg gtggcgcgaa
     5941 ttataaaact tacgataggt taaatagcag gcaataatgg tcgacaagct ggcggttgag
     6001 agcagcataa aggtcaccat aatctgatat ttaatcgcct tcaccggatc aatcccggca
     6061 aatatcagcc cggacatcat tcctggtaaa ctcactaagc caaccgtttt tgctgaatcg
     6121 accgtcggaa ttaaagccgc gcgaatactg tcgcgaatca atatcgctga agcctgcttc
     6181 ggcgtcgcac caagactcag tttctcctga atctgttgct gttcgctaat gacccgttgc
     6241 cctaaattgt tgtaacacaa ccccaccgct accatggcgt taccggcaat catcccggcg
     6301 atagggatca cctgcatcgg gataaattca atcgaccctg agagaatcag caccgccagg
     6361 gtaattcccg ccccgaccgt aatggcaata aacgatgaga taaaagcttt agcaatatat
     6421 ttactgcgtt tttgcgcgtt ccacgccgca ttaaagcaga taaataacac catcaataat
     6481 gtcaggctgg catcatccac gctgaaaata tacttcagca catagccgac aataatcagc
     6541 tgaattatcg ctcgcccgac gctccagaga atatctttct ccagcgccag tttttcttta
     6601 tggctaatta agattgccac caccaccagc attaatgcca gtgctaatga ttcgttagta
     6661 atattatgcg agttcatagc gtgcttcctg catttctccg gcatgcggtt gcagtgtaat
     6721 cactttatcc gcatgattaa tttcgtcttt atcgtgtgtc acccacagca cggcaatatt
     6781 ttgctcgcgc acataacgat ggatcatctc attgacgtta tgtttattac tttcatccag
     6841 cgcactggtt atttcatcca gcaataaaac cttcggcata aattgcaggt tacgaatcaa
     6901 tgagatgcgt tgtttttcac caccagatag ctcggcgata ttcttcgtca aaatgctgtc
     6961 cggcaaggcg aagcgttcga gaaaatcgag aaaaatggct gggtcaggct gccggttacg
     7021 gatctgccag ggaaagatca gattatcgta taccgtatcg ccaaacagcg tcggtgtctg
     7081 ggcgcagtaa gagacttgtt ggcggtagat ttctggcttt agtgtgctga catcctcacc
     7141 ttcaaacagt aacgttccgc tggttgggct gatcaatgaa gcaactattt ttagcagcgt
     7201 acttttgcca caaccagaag gaccggtaat taacttaaat tcgccagcac gcagcgaaaa
     7261 attgatgtta ttaagaatct tcgcatcacc cgccagatat cctacgtttt gtagctgaag
     7321 caaaggacta ttttcctgca tcgctgttcc ctttttctga tttttactaa aaacagttta
     7381 tccttcgcag gaataagggg gaactctctt tcagtaatca ggtataattt gtttaatcaa
     7441 gcagcaattt tgctgattat ggacggtaca acaggaggtt tttccgatgc ttatctttat
     7501 cccgattctc atttttgtcg cgctggtcat tgtcggcgcg ggtgtcaaaa tcgtaccgca
     7561 gggctatcag tggacagtag aacgctttgg tcgctatacc aaaacgttac agccggggct
     7621 cagtctggtg gtgccgttta tggatcgcat tggtcgcaag atcaatatga tggagcaagt
     7681 gctcgatatc ccttcccagg aagttatctc gaaagataac gccaacgtta ccatcgacgc
     7741 cgtgtgcttt attcaggtga ttgacgcgcc gcgcgcggct tatgaagtca gcaatctgga
     7801 gctggcgatc atcaacctga ccatgactaa catccgtacc gtgctgggtt caatggaact
     7861 tgacgaaatg ctctctcagc gcgacagcat caactcacgc ctgctgcgta ttgtcgatga
     7921 agccaccaac ccgtggggga ttaaagtcac ccgtattgaa attcgcgacg tgcgcccacc
     7981 ggcagagctt atctcttcaa tgaacgcgca gatgaaagcg gaacgtacca aacgcgctta
     8041 cattcttgaa gcggaaggga tccgtcaggc ggaaatcctc aaagccgaag gtgaaaaaca
     8101 gtcgcaaatc ctgaaagcgg aaggcgaacg tcagtcggcg tttttacagg ctgaagcgcg
     8161 tgaacgttcc gccgaagcag aagcccgcgc caccaaaatg gtgtctgaag ctatcgcctc
     8221 cggtgatatt caggcggtga actacttcgt agcgcagaaa tacaccgaag cgttacagca
     8281 gatcggttcc tccagtaaca gcaaagtagt gatgatgcca ttagaggcca gcagcctgat
     8341 ggggtcgatt gccgggattg ccgagctggt gaaagacagc gccaacaaac ggactcagcc
     8401 atgatggagt taatggtcgt tcatccacat attttctggc tcagtctcgg cggtttgctg
     8461 ctggcagccg agatgctggg cggaaatggt tatttgttgt ggagcggcgt ggcagcggtg
     8521 attaccggcc tggtggtctg gctggtgccg ctgggttggg agtggcaagg ggtaatgttt
     8581 gccatcctga cgctgctcgc cgcctggctg tggtggaaat ggttgtcgcg gcgggtgcgc
     8641 gaacaaaagc acagcgatag tcatttaaac cagcgcgggc agcagctgat tggccgacgt
     8701 tttgtgctgg aatctccgct ggtcaacggg cgcggtcata tgcgcgtcgg tgacagttca
     8761 tggcctgtca gcgccagcga ggatctcggt gcaggtacgc atgttgaagt cattgcgata
     8821 gaagggataa ccctacatat ccgagccgtc tcgtcttaat caccctgccc gatgatgaca
     8881 gcagccggag agattttcga taatcgggca gtcggcgctg tcatcgccag ggcaggcatt
     8941 cgccagtgcc agcagctggt cgcgcatgga ttgcagctcc tcaatgtgtc gttcgatctc
     9001 cgccaccttc tccagcgtgc gccgtttgac gtcggcgctg tgccgctgcg ggtcgttaaa
     9061 cagattcacc agctcgccgc tctcttccag gttaaagccc acctgccgtg cctggcgcag
     9121 taaggtcagt tcgttgagat gctgctgcgt gtaggtgcga taaccgtttt cgctgcgcat
     9181 cggcggcgtc accagcccct tctcttcata gaagcgaatg gctttgctgg tcaggccggt
     9241 aatttttgct acatcgctga tgttcatcgt tcgcgcaacg cctcctgtgc tttgttaaag
     9301 ggtttcaaca gatattcaag cacgtttttt tgccagtgcg aatatcgacc gccaccacaa
     9361 taatacagga agtactgcgc acagagagat gttatacggt tttattgcgc ttcatgacca
     9421 ttgccacaat aaggctgagt aagagtgagc caataatcca tatcaacgca cggctaccct
     9481 gggaccacag actgtagata aagccaacga tcaccaacaa catcaccaac gtaccaacga
     9541 taagaatcgg caacgaggcg tgaatatcat gacgcaggcg gatcgccacc acaaacaccg
     9601 ccaggtagca aatcaaaaag gtggcgctgg caacgctggc gagtgagcct aaattcagtg
     9661 ccgccgtcat cagcataatc aacaccacga caataatgtt gccccaggta ctctgccgcc
     9721 acagggattt attcattagc ttcggcagtt cgcgttcgct gcccatgttg tccatgatgt
     9781 taaacacggc gaacaggttc gcgttaatgg ctgaagccgt cgccagtaaa gcgccgatga
     9841 cgacgatcac ataacccaca tgcccgagca gcggagaagc agcctgcgct acggcggtat
     9901 cggcatattt ttctaactct aatgccgata catcgctaag caaaaccagt gccagcgaga
     9961 tataaagcaa cgtggtaacg ccaatcgcca ccagaaacgc ccgtggcata atgacctgcg
    10021 gatctttcac tttatccgcc gcgttcgcca tcatgccaaa gcccgcatag gcaaggaaag
    10081 ttatcccaat acaggagaag aacgcaccgg agctgggggg cgcagagacg gaaatatgcg
    10141 ccggttgcag cgaccagaca ccggcaataa tcagcaataa caggatcatc attttaatgc
    10201 cgacgaggat cacttccagc cgccctaccg catggttgct taaggagttg aaaagcgtca
    10261 tcaccgcaat gatccccaac gcgtagagca aaataaggtg ctcctcctgg ctgccttcat
    10321 gcaaaaactg cacggcataa gcgccaaaag cacgggcgac catggcgatg ctcaccgcca
    10381 gcgtcaacag gtacagtaac gagagcgcca gcgaaaagac gccgttgcct aatccgcgac
    10441 gaaagaagtc gataatgccg ccattgctgg gatagctcgc ccccagacgc gcataggcat
    10501 aaccggaaaa catcgccaca ataccgccaa aagcaaaggc gacccaggtc gaggcttcca
    10561 ttagcaatgc agcctgcccc agcagcgcga agatccccgc ccccaccatt gccccaatgc
    10621 cgatggaaac gacgttccat agaccgagag gtttgttacc gttattacct tccgtgttca
    10681 tcatgatcag cccttaaaca cgttatagcc gagttgctta gcgaccgatg ccaccatttt
    10741 ttgaccgcga acactgttgc catcttcgtc cagcggtggt gagaacgcgg caattcccat
    10801 cactccaggg acgaccgcca gaataccgcc acctacaccg cttttgcccg gtaaaccaac
    10861 acgatacgcc cagtcaccgg agcgaccata cagcccttcc atcatcattt cggccagaat
    10921 gtacggcacg ttgtcggcct gaagaacgcg tttatgcgtc aacggattca caccacctgc
    10981 cgccagcgtc gcgccaagcg ttgccagttc aatagtattg aggagcgtgg agcactgacg
    11041 ggtatacacg tcacaggctt ccattgcatc acaatagaga tatccggcgg agtacagcag
    11101 ccaggctatg gcccggttat ggaagttggt tgtttgttcc gactggttga cttcgtcaga
    11161 gagcgctacc tgctcgccag ccagttgctg ttggatatgt aaaattcgct gccagcgttg
    11221 ttcaacattt tcagcgttaa tcaggctggt ggtggcaata gcgccagcat ttaccagtgg
    11281 cgaaagcggt ttgccgccat gcaactctaa ggcgataact gagttaaagg gcaatccggt
    11341 cgggtcagcg ccaattttgt cctgtaccgc ctgcgggccg acatcttcta acgcaagggc
    11401 taacgtacag actttcgaga tggattccag tgcaaagcgg taatcactgt cacccgcact
    11461 atagacgttg ccatcgcagg tcacgatagc cactgccgcc agttgacctg gtacattcgc
    11521 cagaaaggga atgtaatcgg cattttgtcc gccgttaagt gagtgaaatt gggtgtaagc
    11581 ctgatccact gcctgctgta atttgtttgc atctaacatc ttttgttaac tcctttttat
    11641 agatgcggga ggtaattcct caccccggtg ccgattttca ggcatcctga tttaacttag
    11701 cacccgcaac ttaactacag gaaaacaaag agataaatgt ctaatcctga tgcaaatcga
    11761 gccgattttt taatctttac ggacttttac ccgcctggtt tattaatttc ttgaccttcc
    11821 ccttgctgga aggtttaacc tttatcacag ccagtcaaaa ctgtcttaaa ggagtgtttt
    11881 atgtcacaaa ctatcgacct gaccctggac ggcctgtcct gcggtcactg cgttaaacgc
    11941 gtgaaagaaa gtcttgaaca gcgtccggat gttgagcagg cggatgtgtc tatcactgaa
    12001 gcgcacgtta ccgggactgc cagtgcagaa cagctgatcg aaaccatcaa acaagcgggt
    12061 tatgacgcat ctgtaagcca cccaaaggct aaaccgctgg cggagtcatc aatcccgtcg
    12121 gaagcactga cagcggtttc tgaggcgctt ccggcagcga ccgccgatga cgatgacagc
    12181 cagcagttgc tgctgagcgg catgagctgc gccagctgtg tcacccgcgt acaaaatgcg
    12241 ctgcaaagcg taccgggcgt cactcaggca cgggtaaacc tggcggagcg tactgcgctg
    12301 gtgatgggca gtgcctcccc acaagattta gtgcaggcgg tggaaaaagc gggctacggc
    12361 gcggaagcga ttgaagatga cgctaaacgc cgcgagcgcc agcaagaaac cgccgtcgct
    12421 acgatgaagc gcttccgctg gcaggcaatt gtcgcactgg cggtgggtat cccggtgatg
    12481 gtctggggga tgatcggcga taacatgatg gtcaccgctg acaaccgcag cctgtggttg
    12541 gttatcggcc tgataaccct ggcagtgatg gttttcgccg gcggccattt ttaccgcagt
    12601 gcatggaaaa gcctgctgaa cggtgcggcg acgatggata cgctggtggc gctgggtact
    12661 ggcgtggcgt ggctctattc gatgagcgtc aacctgtggc cgcagtggtt cccgatggaa
    12721 gcgcgacatc tttattacga agccagcgcg atgattatcg gtctgatcaa tctcggccat
    12781 atgctggaag cgcgcgcacg ccagcgttct tctaaggcgc tggaaaagtt actcgattta
    12841 accccgccga cggcacgcct ggttactgac gaaggtgaaa aaagcgtgcc tctggcagaa
    12901 gtgcagccag gtatgttgct gcgcctgacg accggcgatc gcgtgccggt agatggcgag
    12961 attacccagg gcgaagcatg gctggatgaa gcgatgctga cgggcgaacc aatcccgcag
    13021 caaaaaggcg aaggcgatag cgtccatgcc gggacagtgg tacaggacgg cagtgtgctg
    13081 tttcgtgcca gtgcggttgg cagccatact acgctgtcac gaatcattcg catggtgcgc
    13141 caggcccaga gcagcaagcc agaaatcggt cagctggcgg ataaaatctc agccgtattt
    13201 gtgccggtag tggtggttat tgcgcttgtc agtgcggcaa tctggtattt ctttggtccg
    13261 gcaccgcaga ttgtctatac cctggtgatt gccaccacgg tactgattat tgcctgtccg
    13321 tgtgcgctgg ggctggcgac gccgatgtcg attatttccg gcgtcgggcg ggcggctgag
    13381 tttggcgtgc tggtgcggga cgctgacgcg ctgcaacgcg ccagtacact cgacactgta
    13441 gtgttcgata aaaccgggac gctgactgaa gggaagccgc aggttgtcgc agtgaaaaca
    13501 tttgctgatg ttgatgaagc gcaggcattg cgtctggcgg cggcactgga gcaaggttcc
    13561 agccatccgc tggcacgagc gatcctcgat aaagcaggtg atatgcagct accgcaggtc
    13621 aacggtttcc gcacattgcg cgggctgggc gtgagcggtg aagctgaagg tcatgcgtta
    13681 ttgctgggca atcaggcgct gttaaatgag caacaggttg gtaccaaagc tatcgaagcg
    13741 gagattactg ctcaggcatc gcaaggggca acgcctgtgc tgctggcggt tgacgggaaa
    13801 gcggtagccc tgctggcagt acgcgatccg ttgcgtagtg atagcgtggc ggcgctgcaa
    13861 cgcctgcata aagcgggata tcgtctggtg atgttgaccg gggataaccc aaccaccgcc
    13921 aatgcgatcg ccaaagaagc agggattgat gaggtgatcg ccggggtgct gccggacggt
    13981 aaagccgaag cgatcaaaca tctgcaaagt gaaggacgtc aggtggcaat ggtgggcgac
    14041 ggcattaacg acgcgccagc gctggctcag gcggatgtcg gcattgcgat gggtggcggc
    14101 agtgatgttg ccattgaaac cgcggcgatt accctgatgc gccatagcct gatgggcgtt
    14161 gcggatgcgc tcgctatttc ccgcgcaacg ctgcacaaca tgaagcagaa cctgctcggt
    14221 gcgtttatct acaacagtat cggtattccg gtcgccgccg gtattttgtg gccgttcact
    14281 ggaacactgc ttaacccggt agttgccgga gcggcaatgg cgctctcgtc gattaccgta
    14341 gtgagtaacg ccaaccggtt gctgcggttt aaaccgaagg aataagtaca tcattgcgga
    14401 tgcgctgctt tagggtggcg catttggcat cgacgcatga ctgccggatg cggcgtaaac
    14461 gccttatccg gcctacggtt caggcacagg tttgtaggcc ggataagacg cgtaagcgtc
    14521 gcatcaggca atggtgctcg gatgccggat gcggcgtgaa cgccttatcc ggcctacgag
    14581 atgaagcgat gttttggcct tacgcgacct tttttgcacg ctcttcacgg cgtgccaaat
    14641 attcagccac tgtttcaatc cgtcccaatt cttcctgggt gcgcatgttg ttttcaactt
    14701 cccaaagatc aaccgccgcc tggaggttta gccaaaaatc gactgtggta tcaaaaactt
    14761 tcgccagacg aaatgccatc tcagtagtga gtttacgatt gttattgatc agtgcactga
    14821 cgctattacg atgaacatgc agcaactctg ctaactcatt gattttcaaa tcgagcggtt
    14881 ccagatattc atagagaaga atatctccgg gtgtcgtcgg ttttcttgtt gcctgtttca
    14941 tggtttttaa ctgttgcttc cttgtgaata gcgatgcaag aacatactga atcatacaaa
    15001 cacattaaac aagtctccaa ctccatttgc gccatccctc accgcgcgct agcatgatat
    15061 ttcacaaagg gaggtcgtat ggatctgttg taccgggtaa aaacgctttg ggccgcgctg
    15121 cgcggtaatc attacacctg gcctgccatc gatatcaccc tccccggcaa tcgccatttt
    15181 catctgattg gcagtattca tatgggtagc cacgatatgg ctcccctgcc cacccgtttg
    15241 ctcaaaaagc tcaaaaacgc cgatgcgctg atcgtcgagg cggatgtttc caccagcgat
    15301 acgccttttg ctaatttgcc tgcctgcgag gcgctggaag agcgcattag cgaggagcaa
    15361 ctccaaaacc tgcagcacat tagccaggag atgggcattt ctccctcact cttttctacc
    15421 caaccgctgt ggcaaatcgc gatggttctt caggcgacgc aggcacaaaa actggggctg
    15481 cgggcagaat acggtatcga ttaccagcta ttgcaggcgg cgaagcaaca acataaaccc
    15541 gtgattgaac tggaaggggc tgaaaaccag attgccatgt tgctccagct ccctgacaaa
    15601 ggactggcgc tgctggacga tacgctgacc cactggcata ccaacgcacg gttgctgcaa
    15661 caaatgatga gctggtggct gaatgcaccg ccgcaaaata atgatataac gctgcccaat
    15721 acgttcagtc agtcgctgta cgatgtgctg atgcatcagc gaaatctcgc ctggcgggat
    15781 aaattacgcc ccatgccgcc ggggcgatat gtggtcgcgg tcggtgcact acacctgtat
    15841 ggagaaggga atttgccgca aatgttgcgc taaaaaaatg gccaatatcg ctattggccc
    15901 gtcaaagagg aatttcattt ttttattatt atgccgtcac tttaagcgac ggtgtaactc
    15961 gattgtcgct caatctcacc atcctgccaa tactcttagg caagatgact cttttttttg
    16021 gaccgccatc aggcgtatgc ttgcttcgtt tttttgttta aggcaggaaa attaccatga
    16081 cacccgcagt taaattactc gaaaaaaaca agatttcgtt tcaaatccat acctacgagc
    16141 acgatccggc tgaaaccaat tttggcgatg aagtcgtcaa aaaattaggt ttgaatccgg
    16201 atcaggtcta caaaacgctg ctggtggcag tgaacggtga tatgaaacac cttgccgtgg
    16261 ccgttacgcc ggtcgcaggt caactggatc ttaaaaaagt agcaaaagcg ctgggtgcca
    16321 agaaagttga gatggccgat ccgatggtcg cgcagcgttc gacgggatac ctggttgggg
    16381 ggattagccc actggggcag aaaaaacgtc tgccaacgat tatcgacgcc cccgcacaag
    16441 aatttgccac tatttatgtt tccggcggca agcgcggact ggatatcgaa ctggcggcag
    16501 gcgatctggc aaagatcctc gatgccaaat ttgctgatat cgcccgccgc gattaagcat
    16561 tgtgccggat gcaaacatcc ggcactttcg gattactgcc agctcacctc acctttcggt
    16621 tcataaacac tcacatccag cggcgagctt ttctggatat acgctttcag cacttcggca
    16681 tcaataaagc cggtattcac atagcccggt ttgttatcaa ggcgcggata tccatcaccg
    16741 ccggtggcat tgaagtttaa tgtcgccata cggtaagttt tcgccggatc gaccggttcg
    16801 cctttgattt taaggtcgtt cagtttgccg tctttcgcca caaagctaac gttggcaaat
    16861 tgcgggtagg cacctgaatc tggcttcatc tgcgcgacgg cggtcaggta atcaatcacc
    16921 tctttaccgg tcatgtcggc atacaccacc acattgccga atggctgcac tttcagcacg
    16981 tttttatagc tgatatcgcc tacttcgata gaatcacgaa ttccgcctcc gctcatcacc
    17041 gcaaagtcgg caccagtgcg atccatttgg gctgccagaa tcaaccgccc catattggtc
    17101 tgtacaaaac gcactttgtc acgatcgcct tccagacgac cattggtttc gcctattttc
    17161 acttccagct gcgctttgcc tttgttctgg aacggtgata acagcgagat catttgctgg
    17221 ttttcagcga tttcaggagt gtaaagcacg cgctcgcttt tcccgtcttc ccaggtcact
    17281 ttcttcttca ggttcaccgg aatcagctgg tagttaacca ttttcatttc gccattacga
    17341 aactcaaaat cagcccgtcc cacgtatttg ccccactcat gcgcctgcac aatccagatg
    17401 ccgttttgtt gatctggttt gcatggcgta cccggcacgt aatcgacctg ttttttgttt
    17461 tctgccgcca tgcagaccgg atcttgcgag tgaccaccga cgatcatcgc cagcgatccg
    17521 gcaggcagcg cgcgtgccat ctccacatcg cccggtgcgt tagagccgtg ctcaccatta
    17581 tcgtaatgcc ccatatgggt cgccgcgata ataatgtctg gcttttctgt ctgttgcagc
    17641 tcctgaatca ccagcttcgc ttcatcggcg ggcttacgaa attcgatatc agtgaagtat
    17701 tccgggttac caatttttgc tgtgtcatcg gttgtcagcc caataacggc aattttcaga
    17761 tcctgacgct taaacagcgc ccacggttta aacaggcgct cgccagtact tttctggtag
    17821 atattcgcgg aaagcaacgg gaacttggcc cacttttcct gctggcgtaa tacggtgagc
    17881 ggattatcaa attcatgatt accgatcgcc atcgcgtcat agcccaccag attcataccg
    17941 cgaaaatcag gttcggcatc ctgtaagtca gactcgggca cgccagtgtt aatgtcgcca
    18001 ccggaaagta gcagcacgct accgccttca gccgcaacct ctttgcggat accatccacc
    18061 agcgtttttt gcgccgccag accatattcg ccatattcat tgcgccaaaa atgcccatga
    18121 tgatcattgg tatgcagaac tgtaattttg taggttttat cctgctcata cgccagagca
    18181 gtttcactcg ccagtgtaaa tgtggttaac agcgctaacg ccacgccccg ctgcaataat
    18241 ttcatacttc tctccctgac ctgatttcaa cgtgttgaaa aatagtatga cgcgacatca
    18301 tagacaagtc tgcgtccggt gaagataaat ctgcatccag attagaaatt ctgtattcgg
    18361 cgttgagact tccttcagac gacgcataca ggtatgttag tctggtaata atcacaaata
    18421 agatcattct ttacatcgca accctgaaaa agtgactttc ctatggcaat gagtgaacaa
    18481 ccccagcctg tggcgggcgc ggctgcgtca acgaccaagg cccgaacatc gtttggtatt
    18541 ttaggtgcta tcagcctctc acatctgctg aacgacatga tccaatcgct gattctggcg
    18601 atttatccgc tgcttcagtc agaattttct ctgacattta tgcagattgg catgataacc
    18661 ctcaccttcc agctcgcctc ttcgctactg caaccagtgg tcggctactg gaccgataaa
    18721 tatccgatgc catggtcgtt gccaattggc atgtgcttta ccttaagcgg tctggtgctg
    18781 cttgcgctgg cgggcagttt tggcgcagtt ctgctggcgg cggcgctggt cggtaccggt
    18841 tcatcggtct ttcatccgga atcttctcgc gtggcccgta tggcttccgg cgggcggcat
    18901 ggcctggcgc aatctatctt tcaggtcggc ggcaactttg gcagttccct gggacccttg
    18961 ctggcggcgg tgattatcgc gccttatggc aaaggcaacg ttgcctggtt tgtgcttgcg
    19021 gcactgctgg cgatcgtggt gttggcgcaa atcagccgtt ggtactcggc acagcaccga
    19081 atgaataaag gaaaacccaa agcgacgatt atcaatccac tgccgcgcaa taaagttgta
    19141 ctggcggtca gcattctgtt aatcctcatt ttctcgaaat atttctatat ggcgagcatc
    19201 agcagctatt acacctttta tctgatgcaa aaattcggat tatctatcca gaatgctcag
    19261 cttcatctgt ttgccttcct gtttgccgtt gcggcaggta cggtgatcgg cgggcctgta
    19321 ggggataaaa ttgggcggaa atatgtgatt tggggctcta tcctcggcgt tgcgccgttt
    19381 acgctgattt taccctacgc cagcctgcac tggacggggg ttttaacggt gattattgga
    19441 tttatcctcg cttcggcatt ctctgccatt ctggtctacg ctcaggagct gcttccagga
    19501 cgtatcggta tggtttctgg actctttttc ggttttgctt ttggcatggg aggtctggga
    19561 gcggcagttc tggggcttat cgccgatcac accagcatcg agttagtcta taaaatctgt
    19621 gctttcctgc cactattggg gatgttgacc atattcctgc ctgataaccg gcataaagac
    19681 tgatttcatt gcagccaaag gcaaactttg gctgcatcgt tttacagtcg ccataagcct
    19741 ttcctctgtt aaaccgcctt ctgttttccg atccgtgctt tttttgcagc taattccatt
    19801 tttctgcaaa attcaataat tattcatgaa catcatcaat gaaattgtca taaactatta
    19861 cctgtaattt tggttttccc ggccaaaaat ggacaataac caccaggaaa aggagacgga
    19921 atgcatcacg ccaccccgct tatcaccacc attgttggcg gccttgtgct cgcctttatc
    19981 ctcggcatgc tggccaataa actacgtatt tctcctctgg tgggatatct gttagcgggt
    20041 gtgctggcag gaccattcac tccgggcttt gttgccgata ccaagcttgc cccggaactg
    20101 gctgaactgg gcgtcattct gttgatgttt ggcgtcggtt tgcacttttc gctgaaggat
    20161 ttgatggcgg taaaggccat cgccattccc ggtgcgatcg cccagatagc cgtggcgacg
    20221 ctgctgggta tggcgctctc tgccgtgctg ggctggtcgt taatgaccgg tatcgtgttc
    20281 ggtttatgtc tttccaccgc cagtaccgtg gtgttactgc gcgcacttga agaacggcaa
    20341 ttaattgaca gtcagcgtgg gcaaatcgcc atcggttggt tgattgtgga agacctggta
    20401 atggttctga cgctggtgtt gctgcccgca gtggcaggaa tgatggaaca gggcgatgtg
    20461 ggctttgcca ctcttgcagt cgatatgggg atcaccatcg gcaaagtgat cgcatttatc
    20521 gccattatga tgctggtagg tcgccgtctg gtgccgtgga ttatggcacg cagcgcggca
    20581 accggttctc gcgagctgtt taccctgtcg gtgctggcgc tggcgttagg ggttgccttt
    20641 ggtgcggtag agctgtttga tgtctccttt gcactcggtg cgttctttgc cgggatggta
    20701 ctgaacgagt ctgaactgag tcaccgtgcc gcccacgata cgctgccatt gcgcgacgcg
    20761 tttgcggtgc tgttttttgt ctccgtcggg atgttgtttg atccgttaat tctgattcag
    20821 caaccgctgg cagtgctggc gacgctggcg attattctgt ttggtaagtc gttagccgca
    20881 tttttcctgg tgcgactgtt tggtcactcc caacgtacgg cattaaccat cgccgccagc
    20941 ctggcgcaga ttggtgagtt cgcgtttatc ctggcgggac tgggaatggc attgaattta
    21001 ctgccgcagg ccggacaaaa cctggtactg gcaggggcga tcctgtcgat tatgctcaac
    21061 ccggtactgt tcgcactact ggagaaatat ctggcgaaga ccgaaacgct ggaagagcag
    21121 acgctggaag aggcaatcga agaagagaag cagatcccag tggatatttg caaccatgcg
    21181 ctactggtgg gttacggtcg tgtaggcagc ctgctggggg agaaattgct cgcctctgat
    21241 attccgctgg tggtgattga gacgtcacga acccgtgttg atgagctgcg agagcgcggg
    21301 gtccgcgcag tattgggcaa tgcggcgaac gaagaaatta tgcaactggc gcatctggaa
    21361 tgtgcaaaat ggctgatcct gacgattccc aacggttatg aagcgggtga gattgtggca
    21421 tctgcccgcg cgaaaaatcc ggatattgag attattgccc gcgcccatta tgacgatgaa
    21481 gtggcgtata tcaccgaacg tggtgcgaat caggtagtga tgggcgagcg tgaaatcgcc
    21541 cgtaccatgc tggaactgct ggaaacgcca ccggcgggtg aggtggtgac ggggtaaacg
    21601 gtggttgccg gatgtaaaat atgaaaaata tgtaggcatg ataagacgcg ccagcgtcgc
    21661 atcaggcatc gagagccaaa tgccagatgc ggcgtgaacg ccttatctgg cctacgaacc
    21721 gacgataact taacgatccc agtaagactc ttccaggctg tcttcacgct ccggcaagcc
    21781 gcgcgttaaa cgaggtgaat gctggttcag tacctgatag ctcacacggt tagcatattt
    21841 acacacctgc gctaacgatg aataagttaa ccaggtgaat ttatgtttgc tggagtttgg
    21901 tacgttgcta cgatggtagc tgttggcggt aatgtcatgc agcaacgctg ccaatgcgcc
    21961 atcccccgct ccattagtgt tcatgatttt ttccggcccg cccatgtacg gcgcaatgtg
    22021 cgaatataca cgcagcggat tctggcaatc cttgtggcgc atggcgcggc taaactcata
    22081 ctggttgaat tccgctatag cgcccggcag cagcggatgc tgggttttac gtttcgcttc
    22141 gtcttcggta aagcccgcca tatacaagcc gattggcccg gcggtgcaca gcaccagatc
    22201 tacccagtcc agcgccttgt cagatgccaa caacggatcg ctttctccgg tcaacgcttc
    22261 ggcttcatct tcgttcatcg caaggataga gacgtgatct ttgaggaatt gctgccacca
    22321 ctgcggattc tcggcaatga caaacttggt gcccagcgtc agcaccaccg gtacgttata
    22381 tttcttcgcg tactcaatgg ctttcatggt tgcttccggc atgggttcac ccggcttgca
    22441 acgcaccaga tatgaggtga gaaccagtgc cgaggctccg gcaatcacat cttccggaat
    22501 gctttcagcc cgcagctggt tcatgtggcc tggactgata gcaaaggtac gttccccgga
    22561 ctcgccaatc agcgtaaagc aacgaccaat cgggccatcc acgccttgta gatagttaag
    22621 atcggtacgg ctggaagtgt tacacaggta acgataggca taactgccaa tttcaatatt
    22681 gctgcacatg acgcccagca gcaccgaacg gtcgtccgcg agcaccgagt agttgtgcat
    22741 ggtgttacca atggtgccac ccgcaaactg atgggtaatc aggtttttct gttttagttc
    22801 ctgataaagc gcttcggcta catcatcctc aatcaccagt gaatgcccgg cgcttaatcc
    22861 ataacgctca ataaattcat catccacttt cgcttcaata tcgaccagcg tttgatcgat
    22921 acccactacc caggcagcgc tggtttcgtt ttctggctgg aattgctgaa gcagcggatc
    22981 gcgtgcgttt acggggaagt aatgtttgga tttacgttta ccgggaaatt tcatggttgt
    23041 ttttacgggt ggttaactga gcggcgaatg ttaacacaat ctgacgggag cgcgcgagac
    23101 gcagccagtt tcaatatcag caggcgggat cgcattttca tggcagtggt tccttacaat
    23161 gacgtaattt gaaaggagtt tttgtatgaa gccggaaaac aaactacctg ttctggacct
    23221 tatttctgct gaaatgaaga ccgttgtgaa tactcttcag ccggatttac cgccctggcc
    23281 cgcaacggga acgattgctg agcaacgaca gtattacacg cttgagcgcc gattctggaa
    23341 tgcgggcgct ccagaaatgg caaccagagc ttacatggtt ccaacaaaat atgggcaggt
    23401 ggaaacacgt ctcttttgtc cgcagccaga tagcccagcg acgctatttt atttgcatgg
    23461 aggcggtttt attctcggca atctcgatac ccacgatcgc atcatgcgcc tgctggcaag
    23521 ctacagccaa tgtacggtga ttggtattga ttacaccctt tcacctgaag cgcgttttcc
    23581 gcaagcgata gaggaaattg tggctgcttg ttgttatttc caccagcagg cggaggatta
    23641 tcaaatcaat atgtcccgca ttggctttgc cggtgattcc gcaggtgcca tgctggcgct
    23701 cgccagtgcg ttgtggttgc gtgataaaca gatcgattgc ggtaaagttg cgggcgtttt
    23761 gctgtggtat gggctttacg gattacggga ttccgtgact cgtcgtctgt tgggcggtgt
    23821 ctgggatggc ttaacgcaac aggatttgca gatgtacgaa gaggcatatt taagcaacga
    23881 cgcggaccgc gagtcgccgt attactgtct gtttaataat gatctcactc gcgaagttcc
    23941 gccctgtttt attgccgggg cggagttcga tccgctgctg gatgacagcc gtctgcttta
    24001 ccagacgtta gcggcgcatc agcagccctg tgagttcaaa ctctacccag gcacgctgca
    24061 cgcctttttg cattattcac ggatgatgaa aaccgccgac gaggctcttc gcgacggcgc
    24121 tcagttcttt accgctcagc tttagcgata cgcggcaaca agattagcca tcatttcgat
    24181 atgttccggc gtggcattaa gcgccggaat atattcatat tttttcccgc cggcaccgag
    24241 gaagacctca cggttttgct cggcaatctc ttccagcgtc tccagacaat ccgcagcaaa
    24301 gcccgggcac atcacctgaa tatgacctac gcctttttct ccgagcattt tcagcgtttc
    24361 gtcggtataa ggcatcagcc agggttcccg accaaagcgc gactgaaagg tcatcatcac
    24421 tttttccggt gccatcccca atgcggaagc cagttcacga gtcgttgtgc ggcaacgttg
    24481 cgggtaatca tcgccttcat ctgcataacg ctggggaatg ccatgataag agagcagtag
    24541 cagatccggt tcgccatgtt tggcaaaaga agcgcgtacg ctgttcgcca gtgcattaat
    24601 gtaatcgtgg ttatcggcgt aatcacgtat aaacgatatc cccggaatgc tacgtttgcg
    24661 cgccagaatg cgtgccagtt catcccatac cgcaccgacc gtagaacagg agaattgcgg
    24721 ataaagcggc agcaccacaa tatgatctac atgctctgcc aggagttcat ctacggcgct
    24781 ttccagtgat ggcgagccgt agctcattcc cagcgctacg ggcatctccg gtaaacgttg
    24841 tgccagcgcc tgctgttgct ggcggctgta aaccatcagc ggcgagccac cttccatcca
    24901 gacagaggca tacagcttcg ccacacgcgg cgagcgcagc ggcaaaatca cgccgcgcag
    24961 caatggccac cataacaacc gtgaggtatc aaccacgcgt ctgtcgctta aaaattgttt
    25021 cagatagcgt tttaccgctt caggtgtggg ggcatcgggc gtacccaggt ttgccagcag
    25081 gataccggtt ttagtctgac gcattaccgc ctcttatcga ttcaacttgt tgataattgt
    25141 agcggaaaag tgaggaagaa gaactaattg ctgtgagagg tcaaatcaga aaaaggaata
    25201 gcgcagattg aggtttttgt aaaaggccga atgaatatcc ggcctgagat tgctgataag
    25261 tttgcttgtg cgggcctgtt cccctcaccc taaccctctc cccgaggggg cgaggggact
    25321 gtccgtgcgc gctttcgaat tagccgagga ttttttccag atcagcgcga acttcagcaa
    25381 ccggcttggt gccgtcaact ttcgcgtatt tggtattacc cgcttctgct tctttggagt
    25441 agtagccgat cagcggtgct gtcatctgat ggtattcaac cagacgttta cgtacggtct
    25501 cttcctgatc atctttacgg gtagtcagtt cttcaccggt aacgtcgtct ttgccttcta
    25561 ctttcggcgg attgaattta acgtgataaa cacgaccaga cggcgcatga acgcggcgac
    25621 cgacgatacg gtcaacgatc agttcgtccg gtacgtcgaa ttccagaacg taatcaacat
    25681 tgatgcccgc ttctttcatc gcgtctgcct gcggaatggt acgcgggaag ccgtccaaca
    25741 ggaaaccatt acggcagtct tcctgagcaa tgcgctcttt aaccagcgcg atcaccagtt
    25801 cgtcggtgac cagtttgcca gcatccataa tgtcttttgc ttgtttaccc agctcggagc
    25861 cagatttgac cgcagcacgc agcatatcgc cagtggagat ttgcggaata ccatatttct
    25921 ccatgatgaa ctgagcctga gtccctttcc ccgcgcccgg agcgccaagc agaatgatac
    25981 gcattgcgaa aatcccctta aaatgtgtcg aattttttga aaaagcgata aacgatacca
    26041 ccaacaggcg attgcctcaa gaaaggcacc tggggctgaa acggttaatg gcgagataat
    26101 ttgcggaaag tgcagatgat gaaaagaaaa atgccggatg acacgaaggt catccggcat
    26161 tacatcagga aaccagcagc tggttcatac gacgaataaa caggttcgga tcttccagcg
    26221 tgccgcgttc tgccagcagc gcctgatcca gcagcagttc tacccactcg ctgaacttcg
    26281 cttcatcttc agtatctgcc gcacgtttca ccagtacgtg atccgggttc agttcgaaga
    26341 tgtatttcac ttctggcact ttctggcccg ccgcagcgaa cagtttcgcc atctgagtgc
    26401 tcatttcgtc cgcgtcggtc gaaacgatcg ctggcgtatc ggtcagacgg tgagtcagac
    26461 ggacatcttt cacgcgctcg ccgagcaggg ctttcacacg gtcgatgaac ggagtcagtg
    26521 ctttctccgc ttctttcgcg ctctcatcaa cttcgtcagc cagtttttca agcgactcgt
    26581 caactttaga caccgactgg aacggtttac cgtcgaactc agtcagatag ttcatcatcc
    26641 actcatcgat gcggtcggaa agcagcagaa cttcgatgcc tttcttacgc agcagttcca
    26701 agtgcgggct gctcttcgct gccgcatagc tgtctgcggt gatgtagtag attttctcct
    26761 gcccttcttt catgcgggaa acgtagtctt ccagagatac ggtctgcgca gaagaatcgg
    26821 tatgggtaga agcaaaacgc agcagtttgg cgatcgcttc ctggttagcg aaatcttccg
    26881 ccggaccttc tttcagtacc aggccaaact gttgccagaa ggtctggtat ttttccgcgt
    26941 cgtctttcgc cagtttttcc agcatttgca gcacacgctt ggtcagcgca ttgcgcaggt
    27001 tacgcgttac cgtgctgtcc tggaggattt cacgggaaac gttcagcggc agatcgctgg
    27061 agtcaatcag accacgcacg aagcgcagat agttcggcat gaactgttct gcgtcgtcca
    27121 tgatgaacac acgctgaaca tacagtttca ggccgtgttt atgatcgcgg ttccacatat
    27181 cccacggagc ctgggacggg atgtacagca ggctggtgta ctcctgctta ccttcaacac
    27241 ggttgtggct ccaggtcagc ggatcattaa agtcgtgggc gatgtgtttg tagaactctt
    27301 tgtactcttc atcggtgatt tccgacttgt tacgagtcca cagcgcctgc gctttgttga
    27361 ttttctccca ggagataacg gtttcgccgt ctttctcttc gcgtttttcg atctctaccg
    27421 gcagcgcgat atggtcggag tatttgctga tgatggaacg cacgcgccag tcatcgagga
    27481 actcgtcttc gccttcacgc agatgcaggg tgatttcagt accacgatct tctttggtga
    27541 tgtcggcaac ggtgtattca ccttcgccag ccgattccca gaagacgcca ttttctggtt
    27601 tttcgcctgc cgcgcgagta cgcacggtca ctttgtcggc cacgataaac gcagagtaga
    27661 aaccaacacc aaactgaccg atcagctggc tgtctttcgc ctggtcagaa cccagggatt
    27721 cgaggaatga tttggtaccg gatttagcga tagtccccag atggtcaatc acttcgtcgc
    27781 gggtcatccc cacgccgtta tcggagatgg tcagcgtacg cttgtcttta tcgaaagaga
    27841 cacgaacgcg tagttcgcca tcaccttcgt acaggtccgg gttagagagc gcacggaaac
    27901 gcagcttgtc cgccgcatcg gaggcgttag agataagctc acgcaggaag atttctttat
    27961 tggaatagag agaatggatc atcaggtgca gaagctgttt cacttctgac tgaaaaccac
    28021 gagtttcttg tcctttcatg taggtctacc tcaataatgc cattttaagg ttaaaaacag
    28081 gatgtgggag agatggggac aagggagaat aatttcaagc gagagcaggt gatcctgctc
    28141 tcgtttgctt aaaaacgaat cttatgacgc ccggcaaggg agtgtgacaa cgtggtgccg
    28201 tcgaccattt ccagctcgcc gccaaccgga acgccatgag cgattcggct ggcttccacg
    28261 tcatattgcg cgcaaagctc ggcaatgtag ttagcggtag cttcaccttc aaccgtgggg
    28321 ttggtggcga ggatcacttc agtgattttt tcctctgcca gacgctgttc cagacgatca
    28381 agcccgatat catccggacc gatgccgtcc agcggtgaca gatgccccat caacacaaaa
    28441 taacgacctg aaaactgccc cgtctgctca atggcgtaga tgtccgccgg actctccacc
    28501 acgcagattt gaccgttttc ctgacgacgc ggattcgaac agatgttaca gacttcctgt
    28561 tcggtgaaag tgcggcaatc ggcgcagtgg ccgatttccg acatcgcccg ggtgagcgcc
    28621 tgcgccagac gcatcccgcc gctacgatcg cgctgaagca gcgtgaacgc catacgctgc
    28681 gccgacttcg ggccaacgcc cggcagacag cgcagtgctt ccataagctg tgttaacagc
    28741 gggctggttt gcatcagaac ggcatcttaa agccaggcgg cagctgcatt ccggaggata
    28801 cagaggccat tttttctttc tgcgtttctt caatacgacg tgctgcgtcg ttgaatgctg
    28861 cagccaccag gtcttccagc atctctttgt cgtcttccag caggctcggg tcgatctcta
    28921 cgcgacggca gttgtgtgca ccgttgatgg tcacttttac cagacctgcg ccagattcgc
    28981 cggtgacttc cagctgcgcg atctcttcct gcattttctg cattttttct tgcatctgct
    29041 gggcttgctt catcaggtta cccagaccgc ctttaccaaa cataggtttc tctctcaatc
    29101 acgttaagga tgacgaacgt aagctgtgct tacgatcaaa tggggcggat actttcttca
    29161 tccagctccg catcgaagaa ccgacgcagg gtctgaatat tattatccgc aataatggac
    29221 tcgcgcgcct gcgcaagttt ttcttcgtat atcgcctgac gccactccag cggcgtacgc
    29281 accgcgggat tatcatcttc aacgatagtc agttcaaccg ttgaaccttt taacatgctc
    29341 aacgcttcag ccagtttttg ctgtgcaccg cggttgttca aatgccgctg agaggagcgc
    29401 aaatgcagac atactgcgtt gtcgctctcc tctttccagg catttaacgc cacctgttcg
    29461 accagttttg gtagcgaaag ttggctcacc tgtgccgccc acgggtcgcg ctcaatggct
    29521 tctgccgcta gcttcgccgc cagttccggc gttttttcat gttccagcgc ttttttcagc
    29581 gccttcggcg tggcgaccac ttctttttgc tgcatcaccg gagtggtcgc cttccagcga
    29641 tacgcttctt ttttggctgg cgctttttcc agcgccgatg gcaccggacg cgcctgaacg
    29701 cgatcggtga ccgaagccag tctttccagc gcagcgttat tcaccggccg cgcgcgggta
    29761 gcggctgccg gttcactctt ttttgctttg gttgctccct gcacgcgctg caactgctgg
    29821 cgcgccgcca gcacctggct ggtggtttcc gggagcggta cagtcggtgc ctgctgcggc
    29881 gctgattgcg gttgcggcgg cacctgggtt ggcgtcatta ctgccgttgg cgcgacgggt
    29941 gcaaaggact gtcgtggcac ttctggctca ggcagcggca tacgcggatg gaatgccagc
    30001 gcgcgcagca gcgtcatctc aacgcccatg cgacggtccg gcgcatacgg taattctttg
    30061 cgaccaatca acagcgtctg atagtaaagc tgaatatccg tcggcggtat ggtgcgcgcc
    30121 agttcacgca tccgcagctc gatggcggcc atgtcgttgc caagtgcagc aggcgaaagt
    30181 tgtaccatcg caatacgatg caacaggccg agcatttcca ccagcaacgc ttcccactcg
    30241 ataccacggg cagcggcttc attaatcagc gccattacgc gctcgccgtt ggcctcgacc
    30301 atcgcttcaa ccagcgacag cgcctgatcg tcgtcaagcg tacccagcat cgcactgacc
    30361 gcctgggttg aaacctggcc gtcaccgctg gcaatcgcct ggtcggtcag acttaaggca
    30421 tctcgcaggc tgccttcagc ggcgcgtgcc agcaattgca gcgcccgcgg ctcgtgagcg
    30481 atatgttctt cgttgaggat gtgctcaagc tgatggcgaa tttgctcgac atccagcgcc
    30541 ttgagatgaa attgcagaca gcgtgacaaa atcgtcaccg gcaatttctg tggatcggtc
    30601 gtcgccagca gaaacttaac gtgctccggc ggctcttcaa gggtttttaa cagtgcgtta
    30661 aagctgtggc gcgacagcat atgcacttcg tcgatcagat aaactttgaa acgaccacgc
    30721 gccggagcgt actggacgtt atccagcagg tcgcgggtat cttcaacttt ggtgcgcgag
    30781 gcggcgtcga tttcaatcag atcgacaaag cgcccctgct cgatttcacg acagttatcg
    30841 cacacgccgc acggcgtcgc ggtaatgccg gtttcgcagt ttagcccctt cgccagcagt
    30901 cgggcgatag aggtttttcc gacgccacgg gtgccggaaa aaagataagc atgatgaata
    30961 cgccctaacg acaagccgtt cgccagtgcg gtcagcacat gttcctggcc gacgacgtca
    31021 gcaaaggttt gtgggcgcca ttttcgggct aagacctgat aactcattgg caggctctga
    31081 aacgctggaa ggtggattca cgaaggggta atgctaacac agccccgtca gaacggcgag
    31141 gctgaatgca catcttgtgc tgtccgtagc gtgggcagca caagactggc gataattaat
    31201 ggcccgggaa cgggacaagg ctgtagctgg taatgccctg tttttcgaga cgctgttcgc
    31261 cgccgagatc gaacaggttg ataatgaacg cagcgtcagc cacttcacca cccagacgac
    31321 ggatcagttt aacggtcgct tcgatagtgc cgccggttgc cagcaggtcg tccaccacca
    31381 gaactttgtc gcccggtttg atggcatcaa cgtggatctc cagctgatcg gtgccgtatt
    31441 ccaggtcgta agtttcactg atggtttcac gcggcagttt gcccggttta cggaccggta
    31501 caaagccaac gcccagaccc agagctaccg gagcgccaaa caagaagcca cgcgcttcgg
    31561 tgccgacaac tttggtaatg cccgcatttt tgtaacgctc aaccagcaag tcgatgctga
    31621 gagcgtaagc tttcgggtct tccagtaagc tggtgacatc gcggaaaaga atgccgggtt
    31681 ttgggtagtc ctgaatgctt ttgatgctat ttttgagata ctcaagctgc tgtgcagtcg
    31741 cggtcataag tgtatgcctg cttgttacgg tggtactcac ggcgcgtttt aaacgtatca
    31801 aaagtaacag ttgtttaacc tttgaccgcc tgcgcctgtg ctcgaaaacg ccagaatgta
    31861 ctggctgtac gcaataattg caactgcgat tgttgtgctt cagtgctttt cttgcttttc
    31921 atcaatcacc ggaattcgcc acatatagaa aagcaaacag gcgagaatta ccagcaacat
    31981 gatgcgcacc catggcatct ggacgaacca cagagaaatg gcaaacgtga gcaaaataag
    32041 caaaatcgcc cgcggtttga cgccgcgcgg catcgcatga tgtttctgcc agaaacgtag
    32101 atagctgcca aaccatgagc ggtacagcaa ccaggcgtga aagcgcgggg aagaacgggc
    32161 aaagcaccag gccgccagca ggataaacgg cgtcgtcggt aataccggta ataccacgcc
    32221 cagcgtaccc agcactaccg ccagccagcc aatgatgatt aaaatgattc gttgcatatt
    32281 gagtgttgtc agcttacaga gtggctactt tagcataaca attatcattt tcattgaggt
    32341 cttatcgtga aaaccgccct gctgctggaa aaactggaag gacagctcgc tacgctgcgt
    32401 cagcgttgtg ccccggtgtc acagttcgcc acgctaagtg ctcgtttcga caggcatctt
    32461 tttcagactc gtgcgacaac actacaggct tgtctcgacg aggcgggcga taatctggct
    32521 gcgcttcgtc atgcagttga gcagcaacag ctgccgcaag tggcctggct ggcggaacat
    32581 ctggcggcac aactggaagc catcgcgcgt gaagcctccg cctggtcatt gcgcgagtgg
    32641 gacagtgcac caccgaaaat tgcccgctgg cagcgtaaac gtattcagca tcaggatttt
    32701 gagcggcggc tacgtgagat ggttgccgaa cgcagagccc gtctggcgcg ggtgaccgat
    32761 ctcgtggaac agcaaacgct gcatcgtgaa gtggaagcct atgaagcgcg cctggcacgc
    32821 tgccgccatg cgctggaaaa aatcgaaaac aggttagcgc gtttaacccg ctagcaatgg
    32881 agagaatatg tcactggaaa atgcccctga cgatgtcaaa ctggctgtcg atttgattgt
    32941 gctgctggag gaaaatcaga tccctgccag taccgtgctg cgcgcgctgg atattgtaaa
    33001 gcgtgattat gaaaagaaat taacgcgcga tgatgaggcg gaaaagtgag aaataaatgg
    33061 ggtcgctaaa tgtcccctaa ggttgcgggc aaacgcaaaa ctgcctgatg cgctacgctt
    33121 atcaggccta caccgctcct gcaatatatt gaattcttgc ggtttcgtag gccggataag
    33181 gcggtcacgc cgcatccggc atgaacaacg cgcactttgt tagcaatctc ggggcaacta
    33241 aatgttgccc cctttcgttt ttaccctacc gctggcgtcg ggtcatcgcc tttgtagtcg
    33301 cgttttactt ccgtcacctc atcgcccttc tcgttgtgca gatgcacttc aagctggtta
    33361 aaggcaatgt tgatgtcgtt ttcacggcac agctgatcga tagtacggtt cagctcatcg
    33421 acagtacgac tacggtcacg cagttcacgc acatacagac gcagctcatg atccaacgtg
    33481 ctggcaccaa atgccgtaaa gaagacttcc ggcattggtt cgtgcatcac ccttgggtgc
    33541 tcagtcgccg ccttcagtaa cactttacgc actttttcca gatcggagcc ataggccacg
    33601 ccgagacgga tcaccagacg cgtagtagtg tcagtcaacg accagttgat cagacgctcg
    33661 gtaacaaacg ctttgttcgg gatgatcact tctttgcgat cgaaatcggt aatcgttgtc
    33721 gcacgaatac ggatcttact taccgtcccc gagaagctac caatggttac cgtatcgcca
    33781 atacgcaccg gacgttcgaa tagaatgatc aaaccggaga cgaagttacc gaaaatttct
    33841 tgtaaaccaa aaccaagacc tacggataat gctgcggcca gccactggag tttatcccaa
    33901 gagacgccca gcgatccgaa caccgtcatc gcaccaacag caataatgat gtagttaagg
    33961 atggtagtaa tggcatacga cgcgccctgg cgcatattca gtcgcgagag caccagcact
    34021 tccagtaaac caggcaggtt gcgaatcaac gcccaggcca ccattgaggc gataatcgca
    34081 aacaacagac tgcccatggt gacgtttttc accaccgcag cgccagcttc agtgccgttg
    34141 taatgccaga gcgtgatgct gtcgagatag ctgaacacgg tgatcaaatc ggaccaaatt
    34201 gcccagaaca tgacaccgaa cagcgcaaac atcagcaaca tggtaatacg cagcgtctgc
    34261 tggttaactt gctccagtgc aatggtgggt tcttccggcg gttcagcacc ttctgcgccc
    34321 tctttcacca gattctgccg acgcgccagc gcacgacgcc aggcgatacg ccgcgccgct
    34381 acgcttaagc cacgcagtac cgtctggtac agcaggttcc agatgatcac cagataaacg
    34441 gtttcaatcc agcgtcctgc cagacgcagc gtagtgtaga agtagcctgt agcagtcagc
    34501 accatcagcg caatcgggat tatcgacagc acggtaatgg tgaccagtcg catggtgtgc
    34561 gactctttat cacgccagct ttcgcggcac atcggccata ccaggaaggc aatcagcagc
    34621 aggttgaaga aaatcatcgc ttgccccagc acatcatcca tcagatgcag cggggaaagt
    34681 tctgccacca cagaccagaa atggataggc agcaatgcga gactgatgcg gacaatttgc
    34741 cgacgccagt ggctggtctg ctgttccggc atgccgaagt gacgtacggc aacgccgttt
    34801 ttctccagta ccttccagca caggccaaac accagccaga atatcgccag ttttttgctg
    34861 aacgaccata gcagttcgct gatgttgagc tgcatggtca acagaatcag gccaaccgcg
    34921 agaataatca ggcacaccgg cagcgcacgg atcaggtcga taaggatcgc ttttggtgtg
    34981 ttgagctggc tgtcgttacg cagggaaccc acagcggaag ccagtttttg ttgatacgct
    35041 ttcagccagc ccagacgcca gtggatcagc ccggcaatca acagcagcgg caaaccagcg
    35101 aggaaagcga taaaaacggc gggccaggct ttttgccagt tcaccgtgat tttcatcgac
    35161 ttaaattcat ctttcaggct ttgcgggaac gctttgatcc agtcccagtc cattggacgg
    35221 ttactgttca cccaaaagat ttgctgagtc aggatggatt tcaggttttt cgacacactc
    35281 attaactgct gctggttgat ttgcaggtta atggccatca tcagctggtt acccaactgt
    35341 ttgttgagtt gatccagcaa ttcgcgacgc atatcaacca cttgcaataa cgcatcgtga
    35401 acttcgctgt tgacttcgtt ggtgtgacct tcttccagtt tgttgacgaa cgcatcgctc
    35461 tggaagagtg catcacgctg ctggttaact tcaaactgtt cgagacgcaa atccgcgatg
    35521 cggttggtca tgttttccag ttcatccgcc gagggcagcg tttgttgttg ctggtaaagg
    35581 atacgagaca acagcaggct gcccttcagg acggcaatct gctctttaat attgcgttcc
    35641 gattgcagcg cccgctccag ccagtttttg actttaatgt tttgctgcat caactgatta
    35701 ccgttttcag tcgcggtaat cagacgctga cttaactgct ggttaatttc cagttcctgc
    35761 ttcaccagcg gattagcctg aatacgcgcg gcttcatccg gggagacggc ttcctgcgcc
    35821 gttttttcgg ttaaagtcag gcgcttgctg tttaccgctt cttgcaacag ttgtaactgg
    35881 tgctccagac gagcgctgtt cgccgtcacg taatcacgtt gcttttgcaa ggtatcctgc
    35941 aagacggtgt tcccttccag gcttttacgc tgctggtcaa tctccgcatt cagcaacgcc
    36001 tgctgggcct gcattaacac tttctggctg ggacgtaagg ctgtctcgcc gacatcagtc
    36061 ccatccagac gactgcgaat ttgttgcagc tgctgcgaag cgttatacat cgcattttgc
    36121 acgcgttcgg gctgcgtctg taacgaaacc agctggctgt tataagacgc cagatcgttt
    36181 tgtgcgtttt gcaaatcgtc cagcgcctgg gcaacgcgag tttccagctg gcgcaacgac
    36241 agcgtgctca gaattttgcg cgtttcttcg tcgttatcga catcgctaag tgctgttaac
    36301 gccgcggtcg cctggcgcat tttttccggc gcttcagcga ctttttgccg tagctgaact
    36361 gtctcttctt ttatgcgatc gattttatcg agggtggcta atgtatctgt cagatcctgc
    36421 tgcaccagtt tgtcctgagc agaaagatct ttttgtttat ttagtgagtc aagttgcgcc
    36481 tgcaggtccg cttttgtcgg cagatcacca ttcgatgacg cccgcgcaaa cgccgtgttc
    36541 tggcataaca agacaaaaac aaaagcaata aatgctgaaa aaacaaaatg ccgtgatcgt
    36601 ttgtaatact ggaacatagt catgatgaat gaaggtttct gaacctgaag aacgacctga
    36661 aaaagtcaaa ccgcaagaat atcacgacgc agtgaaccag aatagcaacg acgaaaatgt
    36721 ccaggaaaaa tcctggagtc agattcaggg ttattcgtta gtggcaggat tacgaagcgt
    36781 ggggcacagg agatacatct ccagtaagat ggcaacgtaa tcgcggactt cttttttaag
    36841 atcaaaagat tgcggggcaa agagccagtt ttccatcagg ccggaaatat agccgcgcat
    36901 aataattgct gcgcgacgcg tcattaaatc cgcaggcaac attttcgctt caatacaatg
    36961 ttttaacgtt tgttctatac ggtcataact ttccagacag agattacgtt gtgcctgttg
    37021 cacaacagcc atttctccga caaattcgca tttgtggaat ataatctcca tcaataatcg
    37081 acgccgttct tctgtcaccg tggattcaag aacatgaatt aatatctctc ttaatactga
    37141 gagtggatcg ccagggaatt ttgcctgata ctcaagctct agttcaccaa tattggattc
    37201 tgacagttcc cagatctcac tgaacaaatc cgacttgtct ttaaaatgcc agtagattgc
    37261 accgcgcgta acgccagctg cttttgcaat ctcgcccagc gaggtggatg ataccccctg
    37321 ctgtgagaaa agacgtagag ccacatcgag gatgtgttgg cgcgtttctt gcgcttcttg
    37381 tttggttttt cgtgccatat gttcgtgaat ttacaggcgt tagatttaca tacatttgtg
    37441 aatgtatgta ccatagcacg acgataatat aaacgcagca atgggtttat taacttttga
    37501 ccattgacca atttgaaatc ggacactcga ggtttacata tgaacaaaaa cagagggttt
    37561 acgcctctgg cggtcgttct gatgctctca ggcagcttag ccctaacagg atgtgacgac
    37621 aaacaggccc aacaaggtgg ccagcagatg cccgccgttg gcgtagtaac agtcaaaact
    37681 gaacctctgc agatcacaac cgagcttccg ggtcgcacca gtgcctaccg gatcgcagaa
    37741 gttcgtcctc aagttagcgg gattatcctg aagcgtaatt tcaaagaagg tagcgacatc
    37801 gaagcaggtg tctctctcta tcagattgat cctgcgacct atcaggcgac atacgacagt
    37861 gcgaaaggtg atctggcgaa agcccaggct gcagccaata tcgcgcaatt gacggtgaat
    37921 cgttatcaga aactgctcgg tactcagtac atcagtaagc aagagtacga tcaggctctg
    37981 gctgatgcgc aacaggcgaa tgctgcggta actgcggcga aagctgccgt tgaaactgcg
    38041 cggatcaatc tggcttacac caaagtcacc tctccgatta gcggtcgcat tggtaagtcg
    38101 aacgtgacgg aaggcgcatt ggtacagaac ggtcaggcga ctgcgctggc aaccgtgcag
    38161 caacttgatc cgatctacgt tgatgtgacc cagtccagca acgacttcct gcgcctgaaa
    38221 caggaactgg cgaatggcac gctgaaacaa gagaacggca aagccaaagt gtcactgatc
    38281 accagtgacg gcattaagtt cccgcaggac ggtacgctgg aattctctga cgttaccgtt
    38341 gatcagacca ctgggtctat caccctacgc gctatcttcc cgaacccgga tcacactctg
    38401 ctgccgggta tgttcgtgcg cgcacgtctg gaagaagggc ttaatccaaa cgctatttta
    38461 gtcccgcaac agggcgtaac ccgtacgccg cgtggcgatg ccaccgtact ggtagttggc
    38521 gcggatgaca aagtggaaac ccgtccgatc gttgcaagcc aggctattgg cgataagtgg
    38581 ctggtgacag aaggtctgaa agcaggcgat cgcgtagtaa taagtgggct gcagaaagtg
    38641 cgtcctggtg tccaggtaaa agcacaagaa gttaccgctg ataataacca gcaagccgca
    38701 agcggtgctc agcctgaaca gtccaagtct taacttaaac aggagccgtt aagacatgcc
    38761 taatttcttt atcgatcgcc cgatttttgc gtgggtgatc gccattatca tcatgttggc
    38821 aggggggctg gcgatcctca aactgccggt ggcgcaatat cctacgattg caccgccggc
    38881 agtaacgatc tccgcctcct accccggcgc tgatgcgaaa acagtgcagg acacggtgac
    38941 acaggttatc gaacagaata tgaacggtat cgataacctg atgtacatgt cctctaacag
    39001 tgactccacg ggtaccgtgc agatcaccct gacctttgag tctggtactg atgcggatat
    39061 cgcgcaggtt caggtgcaga acaaactgca gctggcgatg ccgttgctgc cgcaagaagt
    39121 tcagcagcaa ggggtgagcg ttgagaaatc atccagcagc ttcctgatgg ttgtcggcgt
    39181 tatcaacacc gatggcacca tgacgcagga ggatatctcc gactacgtgg cggcgaatat
    39241 gaaagatgcc atcagccgta cgtcgggcgt gggtgatgtt cagttgttcg gttcacagta
    39301 cgcgatgcgt atctggatga acccgaatga gctgaacaaa ttccagctaa cgccggttga
    39361 tgtcattacc gccatcaaag cgcagaacgc ccaggttgcg gcgggtcagc tcggtggtac
    39421 gccgccggtg aaaggccaac agcttaacgc ctctattatt gctcagacgc gtctgacctc
    39481 tactgaagag ttcggcaaaa tcctgctgaa agtgaatcag gatggttccc gcgtgctgct
    39541 gcgtgacgtc gcgaagattg agctgggtgg tgagaactac gacatcatcg cagagtttaa
    39601 cggccaaccg gcttccggtc tggggatcaa gctggcgacc ggtgcaaacg cgctggatac
    39661 cgctgcggca atccgtgctg aactggcgaa gatggaaccg ttcttcccgt cgggtctgaa
    39721 aattgtttac ccatacgaca ccacgccgtt cgtgaaaatc tctattcacg aagtggttaa
    39781 aacgctggtc gaagcgatca tcctcgtgtt cctggttatg tatctgttcc tgcagaactt
    39841 ccgcgcgacg ttgattccga ccattgccgt accggtggta ttgctcggga cctttgccgt
    39901 ccttgccgcc tttggcttct cgataaacac gctaacaatg ttcgggatgg tgctcgccat
    39961 cggcctgttg gtggatgacg ccatcgttgt ggtagaaaac gttgagcgtg ttatggcgga
    40021 agaaggtttg ccgccaaaag aagctacccg taagtcgatg gggcagattc agggcgctct
    40081 ggtcggtatc gcgatggtac tgtcggcggt attcgtaccg atggccttct ttggcggttc
    40141 tactggtgct atctatcgtc agttctctat taccattgtt tcagcaatgg cgctgtcggt
    40201 actggtggcg ttgatcctga ctccagctct ttgtgccacc atgctgaaac cgattgccaa
    40261 aggcgatcac ggggaaggta aaaaaggctt cttcggctgg tttaaccgca tgttcgagaa
    40321 gagcacgcac cactacaccg acagcgtagg cggtattctg cgcagtacgg ggcgttacct
    40381 ggtgctgtat ctgatcatcg tggtcggcat ggcctatctg ttcgtgcgtc tgccaagctc
    40441 cttcttgcca gatgaggacc agggcgtgtt tatgaccatg gttcagctgc cagcaggtgc
    40501 aacgcaggaa cgtacacaga aagtgctcaa tgaggtaacg cattactatc tgaccaaaga
    40561 aaagaacaac gttgagtcgg tgttcgccgt taacggcttc ggctttgcgg gacgtggtca
    40621 gaataccggt attgcgttcg tttccttgaa ggactgggcc gatcgtccgg gcgaagaaaa
    40681 caaagttgaa gcgattacca tgcgtgcaac acgcgctttc tcgcaaatca aagatgcgat
    40741 ggttttcgcc tttaacctgc ccgcaatcgt ggaactgggt actgcaaccg gctttgactt
    40801 tgagctgatt gaccaggctg gccttggtca cgaaaaactg actcaggcgc gtaaccagtt
    40861 gcttgcagaa gcagcgaagc accctgatat gttgaccagc gtacgtccaa acggtctgga
    40921 agataccccg cagtttaaga ttgatatcga ccaggaaaaa gcgcaggcgc tgggtgtttc
    40981 tatcaacgac attaacacca ctctgggcgc tgcatggggc ggcagctatg tgaacgactt
    41041 tatcgaccgc ggtcgtgtga agaaagttta tgtcatgtca gaagcgaaat accgtatgct
    41101 gccggatgat atcggcgact ggtatgttcg tgctgctgat ggtcagatgg tgccattctc
    41161 ggcgttctcc tcttctcgtt gggagtacgg ttcgccgcgt ctggaacgtt acaacggcct
    41221 gccatccatg gaaatcttag gccaggcggc accgggtaaa agtaccggtg aagcaatgga
    41281 gctgatggaa caactggcga gcaaactgcc taccggtgtt ggctatgact ggacggggat
    41341 gtcctatcag gaacgtctct ccggcaacca ggcaccttca ctgtacgcga tttcgttgat
    41401 tgtcgtgttc ctgtgtctgg cggcgctgta cgagagctgg tcgattccgt tctccgttat
    41461 gctggtcgtt ccgctggggg ttatcggtgc gttgctggct gccaccttcc gtggcctgac
    41521 caatgacgtt tacttccagg taggcctgct cacaaccatt gggttgtcgg cgaagaacgc
    41581 gatccttatc gtcgaattcg ccaaagactt gatggataaa gaaggtaaag gtctgattga
    41641 agcgacgctt gatgcggtgc ggatgcgttt acgtccgatc ctgatgacct cgctggcgtt
    41701 tatcctcggc gttatgccgc tggttatcag tactggtgct ggttccggcg cgcagaacgc
    41761 agtaggtacc ggtgtaatgg gcgggatggt gaccgcaacg gtactggcaa tcttcttcgt
    41821 tccggtattc tttgtggtgg ttcgccgccg ctttagccgc aagaatgaag atatcgagca
    41881 cagccatact gtcgatcatc attgatacaa cgtgtaatca ctaaggccgc gtaagcggcc
    41941 ttttttatgc ataacctacg aacattaagg agtaattgaa ccaccaactc aggatctcat
    42001 ac
//
LOCUS       DACAOP010000032        41019 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.032, whole genome shotgun sequence.
ACCESSION   DACAOP010000032 DACAOP010000000
VERSION     DACAOP010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41019
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.032"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..242)
                     /locus_tag="IT892_001904"
     CDS             complement(<1..242)
                     /locus_tag="IT892_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HAP3135128.1"
                     /translation="MDQKLLTDFRSELLDSRFGAKAISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSI"
     gene            complement(453..1850)
                     /gene="ccp"
                     /locus_tag="IT892_001905"
     CDS             complement(453..1850)
                     /gene="ccp"
                     /locus_tag="IT892_001905"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HAP3135129.1"
                     /translation="MKMVSRITAIGLAGVAICYLGLSGYVWYHDNKRSKQADVQASAV
                     SENNKVLGFLREKGCDYCHTPSAELPAYYYIPGAKQLMDYDIKLGYKSFNLEAVRAAL
                     LADKPVSQSDLNKIEWVMQYETMPPTRYTALHWAGKVSDEERAEILAWIAKQRAEYYA
                     SNDTAPEHRNEPVQPIPQKLPTDAQKVALGFALYHDPRLSADSTISCAHCHALNAGGV
                     DGRKTSIGVGGAVGPINAPTVFNSVFNVEQFWDGRAATLQDQAGGPPLNPIEMASKSW
                     DEIIAKLEKDPQLKTQFLEVYPQGFSGENITDAIAEFEKTLITPDSPFDKWLRGDENA
                     LTAQQKKGYQLFKDNKCATCHGGIILGGRSFEPLGLKKDFNFGEITAADIGRMNVTKE
                     ERDKLRQKVPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGKELPQEDVDDIVAFL
                     HSLNGVYTPYMQDKQ"
     gene            2254..3903
                     /gene="treF"
                     /locus_tag="IT892_001906"
     CDS             2254..3903
                     /gene="treF"
                     /locus_tag="IT892_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase TreF"
                     /protein_id="HAP3135130.1"
                     /translation="MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMI
                     EGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRD
                     FDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQ
                     SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYY
                     LSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMP
                     DGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRD
                     TGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRY
                     LWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGIL
                     ASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKLI
                     EKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP"
     gene            complement(3954..4556)
                     /locus_tag="IT892_001907"
     CDS             complement(3954..4556)
                     /locus_tag="IT892_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP3135131.1"
                     /translation="MQIVMFDRQSIFIHGMKISLQQRIPGVSIQGASQADELWQKLES
                     YPEALVMLDGDQDGEFCYWLLQKTVVQFPEVKVLITATDCNKRWLQEVIHFNVLAIVP
                     RDSTVETFALAVNSAAMGMMFLPGDWRTTPEKDIKDLKSLSARQREILTMLAAGESNK
                     EIGRALNISTGTVKAHLESLYRRLEVKNRTQAAMMLNISS"
     gene            5004..5975
                     /locus_tag="IT892_001908"
     CDS             5004..5975
                     /locus_tag="IT892_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3135132.1"
                     /translation="MLEKTINNAICALLFRCEQQSVKEMDKIHAMQLFIKVAELESFS
                     RAADFFALPKGSVSRQIQALEHQLGTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLSE
                     LDGLFQQDATSISGKLRIDIPPGIAKSLLLPRLSEFLYLHPGIELELSSHDRPVDILH
                     DGFDCVIRTGALPEDGVIARPLGKLTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTP
                     HLGVHPLGFEVASVNGVQWFKSGGMLTVNSSENYLTAGLAGLGIIQIPRIAVREALRA
                     GRLIEVLPGYRAEPLSLSLVYPQRRELSRRVNLFMQWLAGVMKEYLD"
     gene            6024..7037
                     /gene="yhjD"
                     /locus_tag="IT892_001909"
     CDS             6024..7037
                     /gene="yhjD"
                     /locus_tag="IT892_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YhjD"
                     /protein_id="HAP3135133.1"
                     /translation="MTQENEIKRPIQDLEHEPIKPLDNSEKGSKVSQALETVTTTAEK
                     VQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLASHPML
                     LQDIFDKILQNISDPTLAATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAI
                     RAQSRDVWERSPQDQEKFWVKYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALH
                     LNSIEWLKPTWRLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVI
                     KIVMTYTLPSLMKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDPRMPGK
                     TQP"
     gene            7448..8770
                     /locus_tag="IT892_001910"
     CDS             7448..8770
                     /locus_tag="IT892_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HAP3135134.1"
                     /translation="MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATA
                     AVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIGSAVFGHFGDRVGRKATLVASLL
                     TMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
                     LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVS
                     LHESPVFEKVAKAKKQVKIPLGTLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFST
                     AAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIILFALF
                     AFNPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASI
                     LGASVAPYIAAWLQTNYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL"
     gene            complement(8952..11012)
                     /locus_tag="IT892_001911"
     CDS             complement(8952..11012)
                     /locus_tag="IT892_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HAP3135135.1"
                     /translation="MSKAGKITAAISGAFLLLIVVAIILIATFDWNRLKPTINQKVSA
                     ELNRPFAIRGDLGVVWERQKQETGWRSWVPWPHVHAEDIILGNPPDIPEVTMVHLPRV
                     EATLAPLALLTKTVWLPWIKLGKPDARLIRLSEKNNNWTFNLANDDNKDANAKPSAWS
                     FRLDNILFDQGRIAIDDKVSKADLEIFVDPLGKPLPFSEVTGSKGKADKEKVGDYVFG
                     LKAQGRYNGEPLTGTGKIGGMLALRGEGTPFPVQADFRSGNTRVAFDGVVNDPMKMGG
                     VDLRLKFSGDSLGDLYELTGVLLPDTPPFETDGRLVAKIDTEKSSVFDYRGFNGRIGD
                     SDIHGSLVYTTGKPRPKLEGDVESRQLRLADLGPLIGVDSGKGAEKSKRSEQKKGEKS
                     VQPAGKVLPYDRFETDKWDVMDGDVRFKGRRIEHGSSLPISDLSTHIILKNADLRLQP
                     LKFGMAGGSIAANIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGEMNGDAE
                     LRGSGNSVAALLGNSNGNLKLLMNDGLVSRNLMEIVGLNVGNYIVGAIFGDDEVRVNC
                     AAANLNIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSP
                     LYVRGTFKNPQAGVKAGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILS
                     QMKK"
     gene            complement(11082..11849)
                     /gene="pdeH"
                     /locus_tag="IT892_001912"
     CDS             complement(11082..11849)
                     /gene="pdeH"
                     /locus_tag="IT892_001912"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417982.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase"
                     /protein_id="HAP3135136.1"
                     /translation="MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRL
                     MAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFIEHGLLA
                     SVNIDGPTLIALRQQPKILRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
                     GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVE
                     TPEEWRDVQNSPAFAAQGWFLSRPAPIETLNTAVLAL"
     gene            12081..13010
                     /locus_tag="IT892_001913"
     CDS             12081..13010
                     /locus_tag="IT892_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygluconokinase"
                     /protein_id="HAP3135137.1"
                     /translation="MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
                     ALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYY
                     WRNEAAAKFWLESEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
                     GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTH
                     NAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLT
                     GGSAEDAAKRGHLTASTVIQYRGAIIPREAMPA"
     gene            complement(13106..14602)
                     /locus_tag="IT892_001914"
     CDS             complement(13106..14602)
                     /locus_tag="IT892_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP3135138.1"
                     /translation="MQGTKIRLLAGGLLMMATAGYVQADALQPDPAWQQGTLSNGLQW
                     QVLTTPQRPSDRVEIRLLVNTGSLAESTQQSGYSHAIPRIALTQSGGLDAAQARSLWQ
                     QGIDPKRPMPPVIVSYDTTLFNLSLPNNRNDLLKEALSYLANATGKLTITPETINHAL
                     QSQDMVATWPADTKEGWWRYRLKGSTLLGHDPADPLKQPVEAEKIKDFYQKWYTPDAM
                     TLLVVGNVDARSVVDQINKTFGELKGKRETPAPVPTLSPLRAEAVSIMTDAVRQDRLS
                     IMWDTPWQPIRESAALLRYWRADLAREALFWHVQQALSASNSKDIGLGFDCRVLYLRA
                     QCAINIESPNDKLNSNLNLVARELAKVRDKGLPEEEFNALVAQKKLELQKLFAAYARA
                     DTDILMGQRMRSLQNQVVDIAPEQYQKLRQDFLNSLTVEMLNQDLRQQLSNDMALILL
                     QPKGEPEFNMKALQAVWDQIMAPSTAAATTSVATDDVHPEVTDIPPAQ"
     gene            complement(14823..16109)
                     /locus_tag="IT892_001915"
     CDS             complement(14823..16109)
                     /locus_tag="IT892_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HAP3135139.1"
                     /translation="MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKL
                     IKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPG
                     AGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLF
                     GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQ
                     LGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRM
                     LDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLI
                     VLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNG
                     VATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS"
     gene            complement(16292..18280)
                     /gene="hmsP"
                     /locus_tag="IT892_001916"
     CDS             complement(16292..18280)
                     /gene="hmsP"
                     /locus_tag="IT892_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator HmsP"
                     /protein_id="HAP3135140.1"
                     /translation="MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTAT
                     QLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIP
                     ERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLV
                     TIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPAKELVGHQLALPRLHQDDEIG
                     MLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIIT
                     CETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHA
                     ITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGK
                     NQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQ
                     QPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQL
                     MHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDF
                     GMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLAQSLNLQMIAEGVE
                     TEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK"
     gene            complement(18362..21835)
                     /gene="bcsC"
                     /locus_tag="IT892_001917"
     CDS             complement(18362..21835)
                     /gene="bcsC"
                     /locus_tag="IT892_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026226.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsC"
                     /protein_id="HAP3135141.1"
                     /translation="MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHRE
                     DLVQQSLYRLELIDPNNPDVVAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSR
                     TTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIP
                     ARRGEAINQLKRINADAPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGAS
                     KIWYGQIKDMPVSDASVSALKKYLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQG
                     LAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALALDP
                     HSSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLG
                     DVAMARKDYPAAERYYQQTLRMDSGNTNAVRGLANIYRQQSPEKAEAFIASLSASQRR
                     SIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALDPGSVWITYRLSQDLWQA
                     GQRSQADTLMRNLAQQKSNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWNSNIQE
                     LVNRLQSDQVLETANRLRESGKEAEAEAMLRQQPPSTRIDLTLADWAQQRRDYTAARA
                     AYQNVLTREPANADAILGLTEVDIAAGDKAAARSQLAKLPATDNASLNTQRRVALAQA
                     QLGDTAAAQRTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPTQALETYKDAMVA
                     SGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGT
                     GGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDC
                     SGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISYSDDIGPLGYTVNAH
                     RRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLTG
                     KNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEY
                     LSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDG
                     GSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGWQGDMDL
                     PPQPLIPYADW"
     gene            complement(21901..22923)
                     /gene="bcsZ"
                     /locus_tag="IT892_001918"
     CDS             complement(21901..22923)
                     /gene="bcsZ"
                     /locus_tag="IT892_001918"
                     /EC_number="3.2.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001333832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase"
                     /protein_id="HAP3135142.1"
                     /translation="MNVLRSGIVTMLLLAAFSVQAACTWPAWEQFKKDYISQEGRVID
                     PSDARKITTSEGQSYGMFSALAANDRAAFDNILDWTQNNLAQGSLKERLPAWLWGKKE
                     NSKWEVLDSNSASDGDVWMAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLG
                     SMLLPGKVGFAEDNSWRFNPSYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFS
                     PDWVRYEKDKGWQLKAEKTLISSYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTE
                     KNGYPPEKVDVATGKAQGKGPVGFSAAMLPFLQNRDAQAVQRQRVADNFPGSDAYYNY
                     VLTLFG"
     gene            complement(22930..25269)
                     /gene="bcsB"
                     /locus_tag="IT892_001919"
     CDS             complement(22930..25269)
                     /gene="bcsB"
                     /locus_tag="IT892_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HAP3135143.1"
                     /translation="MKRKLFWICAVAMGMSAFPSFMTQATPATQPLINAEPAVAAQTE
                     QNPQVGQVMPGVQGADAPVVAQNGPSRDVKLTFAQIAPPPGSMVLRGINPNGSIEFGM
                     RSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPIN
                     PLFITDFNRVRLEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPV
                     PFFDPRDNRTNTLPMVFAGAPDVGLQQASAIVASWFGSRSGWRGQNFPVLYNQLPDRN
                     AIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNPYVKLLVVFGRDDKDLLQAAKGIAQ
                     GNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAI
                     NVSLNLPPDLYLMRSTGIDMDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEAN
                     RLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMNPMPGGSVDNCITFQPVQN
                     HVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTITVMPKAPNEAQMET
                     LLNTVGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIIGGIPDKLKDDKQIDLLVQAT
                     ESWVKTPMRQTPFPGIVPDESDRAAETRSTLTSSGAMAAVIGFQSPYNDQRSVIALLA
                     DSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHLPWFERVWYAL
                     ANHPILLAVLAAISVILLAWVLWRLLRIISRRRLNPDNE"
     gene            complement(25280..27898)
                     /gene="bcsA"
                     /locus_tag="IT892_001920"
     CDS             complement(25280..27898)
                     /gene="bcsA"
                     /locus_tag="IT892_001920"
                     /EC_number="2.4.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417990.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-forming cellulose synthase catalytic
                     subunit"
                     /protein_id="HAP3135144.1"
                     /translation="MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWMILA
                     WIFIPLEHPRWQRIRAEHKNLYPHINASRPRPLDPVRYLIQTCWLLIGASRKETPKPR
                     RRAFSGLQNIRGRYHQWMNELPERVSHKTQHLDEKKELGHLSAGARRLILGIIVTFSL
                     ILALICVTQPFNPLAQFIFLMLLWGVALIVRRMPGRFSALMLIVLSLTVSCRYIWWRY
                     TSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVD
                     IFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGREEFRQFAQNVGVKYIART
                     THEHAKAGNINNALKYAKGEFVSIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHF
                     FSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIA
                     VETVTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWARGMVQIFRLD
                     NPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPALMIALFV
                     LPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGG
                     LVEEEYVDWVISRPYIFLVLLNLVGVAVGIWRYFYGPPTEMLTVVVSMVWVFYNLIVL
                     GGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCTVQDFSDGGLGIKINGQAQIL
                     EGQKVNLLLKRGQQEYVFPTQVARVMGNEVGLKLMPLTTQQHIDFVQCTFARADTWAL
                     WQDSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRVLTSLVSWVVSFIPRRP
                     ERSETAQPSDQALAQQ"
     gene            complement(27895..28647)
                     /gene="bcsQ"
                     /locus_tag="IT892_001921"
                     /pseudo
     CDS             complement(27895..28647)
                     /gene="bcsQ"
                     /locus_tag="IT892_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709309.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsQ"
     gene            complement(28659..28847)
                     /locus_tag="IT892_001922"
     CDS             complement(28659..28847)
                     /locus_tag="IT892_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135145.1"
                     /translation="MNNNEPDTLPDPAIGYIFQNDIVALKQAFSLPDIDYADISQREQ
                     LAAALKRWPLLAEFAQQK"
     gene            29120..30691
                     /gene="bcsE"
                     /locus_tag="IT892_001923"
     CDS             29120..30691
                     /gene="bcsE"
                     /locus_tag="IT892_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsE"
                     /protein_id="HAP3135146.1"
                     /translation="MRDIVDPVFSIGISSLWDELRHMPAGGVWWFNVDRHEDAISLAN
                     QTIASQAETAHVAVISMDSDPAKIFQLDDSQGPEKIKLFSMLNHEKGLYYLTRDLQCS
                     IDPHNYLFILVCANNAWQNIPAERLRSWLDKMNKWSRLNHCSLLVINPGNNNDKQFSL
                     LLEEYRSLFGLASLRFQGDQHLLDIAFWCNEKGVSARQQLSVQQQNGIWTLVQSEEAE
                     IQPRSDEKRILSNVAVLEGAPPLSEHWQLFNNNEILFNEARTAQAATVVFSLQQNAQI
                     EPLARSIHTLRRQRGSAMKILVRENTASLRATDERLLLACGANMVIPWNAPLSRCLTM
                     IESVQGQKFSRYVPEDITTLLSMTQPLKLRGFQKWDVFCNAVNNMMNNPLLPAHGKGV
                     LVALRPVPGIRVEQALTLCRPNRTGDIMTIGGNRLVLFLSFCRINDLDTALNHIFPLP
                     TGDIFSNRMVWFEDDQISAELVQMRLLAPEQWGMPLPLTQGSKPVINAEHDGRHWRRI
                     PEPMRLLDDAVERSS"
     gene            30688..30879
                     /gene="bcsF"
                     /locus_tag="IT892_001924"
     CDS             30688..30879
                     /gene="bcsF"
                     /locus_tag="IT892_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsF"
                     /protein_id="HAP3135147.1"
                     /translation="MMTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPR
                     YVKPAGTLRRTEKARATKK"
     gene            30876..32555
                     /gene="bcsG"
                     /locus_tag="IT892_001925"
     CDS             30876..32555
                     /gene="bcsG"
                     /locus_tag="IT892_001925"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="HAP3135148.1"
                     /translation="MTQFTQNTAMPSSLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHP
                     LLNLVFAAFLLMPLPRYSLHRLRHWIALPIGFALFWHDTWLPGPESIMSQGSQVAGFS
                     TDYLIDHVTRFINWQMIGAIFVLLVAWLFLSQWIRITVFVVAILLWLNVLTLAGPSFS
                     LWPAGQPTTTVTTTGGNAAATVAATGGAPVVGDMPAQTAPPTTANLNAWLNNFYNAEA
                     KRKSTFPSSLPADAQPFELLVINICSLSWSDIEAAGLMSHPLWSHFDIEFKNFNSATS
                     YSGPAAIRLLRASCGQTSHTNLYQPANNDCYLFDNLSKLGFTQHLMMGHNGQFGGFLK
                     EVRENGGMQSELMDQTNLPVILLGFDGSPVYDDTAVLNRWLDVTEKDKNSRSATFYNT
                     LPLHDGNHYPGVSKTADYKARAQKFFDELDAFFTELEKSGRKVMVVVVPEHGGALKGD
                     RMQVSGLRDIPSPSITDVPVGVKFFGMKAPHQGAPIVIEQPSSFLAISDLVVRVLDGK
                     IFTEDNVDWKKLTSGLPQTAPVSENSNAVVIQYQDKPYVRLNGGDWVPYPQ"
     gene            complement(32642..32749)
                     /gene="ldrD"
                     /locus_tag="IT892_001926"
     CDS             complement(32642..32749)
                     /gene="ldrD"
                     /locus_tag="IT892_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxic polypeptide
                     LdrD"
                     /protein_id="HAP3135149.1"
                     /translation="MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK"
     gene            33225..34496
                     /locus_tag="IT892_001927"
     CDS             33225..34496
                     /locus_tag="IT892_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HAP3135150.1"
                     /translation="MQHNTLSKHNQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGL
                     KGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCNDYTDIISHYLGKNWGIFLGVIYF
                     LMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLF
                     KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQ
                     VLNPMNIAYRKREADKVLATRLALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAF
                     EQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHEAIKGIILNLLSRII
                     DTKKINSRVLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKV
                     AQLEKLRGFKAWLILLYGILLCLSPLLKLIE"
     gene            complement(34526..35530)
                     /gene="dppF"
                     /locus_tag="IT892_001928"
     CDS             complement(34526..35530)
                     /gene="dppF"
                     /locus_tag="IT892_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP binding subunit
                     DppF"
                     /protein_id="HAP3135151.1"
                     /translation="MSTQEATLQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGVSFN
                     LERGKTLAVVGESGCGKSTLGRLLTMIEMPTGGELYYQGQDLLKHDPQAQKLRRQKIQ
                     IVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALSMMAKVGLKTEHYDRYPH
                     MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFI
                     SHDLSVVEHIADEVMVMYLGRCVEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRER
                     IKLSGELPSPLNPPPGCAFNARCRRRFGPCTQLQPQLKDYGGQLVACFAVDQDENPQR
                     "
     gene            complement(35527..36510)
                     /gene="dppD"
                     /locus_tag="IT892_001929"
     CDS             complement(35527..36510)
                     /gene="dppD"
                     /locus_tag="IT892_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HAP3135152.1"
                     /translation="MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGS
                     GKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSL
                     NPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ
                     RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVA
                     EAAHKIIVMYAGQVVETGDAHAIFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPG
                     KYDRPNGCLLNPRCPYATDRCRAEEPALNMLADGRQSKCHYPLDDAGRPTL"
     gene            complement(36521..37423)
                     /gene="dppC"
                     /locus_tag="IT892_001930"
     CDS             complement(36521..37423)
                     /gene="dppC"
                     /locus_tag="IT892_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010426221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppC"
                     /protein_id="HAP3135153.1"
                     /translation="MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLF
                     IAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSL
                     LVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
                     IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAP
                     LIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI
                     LLTVLAFNLMGDGLRDALDPKLKQ"
     gene            complement(37433..38452)
                     /gene="dppB"
                     /locus_tag="IT892_001931"
     CDS             complement(37433..38452)
                     /gene="dppB"
                     /locus_tag="IT892_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppB"
                     /protein_id="HAP3135154.1"
                     /translation="MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGI
                     SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLEL
                     GVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
                     NLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLA
                     VIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLA
                     GAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPR
                     IRHKK"
     gene            complement(38760..40367)
                     /gene="dppA"
                     /locus_tag="IT892_001932"
     CDS             complement(38760..40367)
                     /gene="dppA"
                     /locus_tag="IT892_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter substrate-binding
                     protein DppA"
                     /protein_id="HAP3135155.1"
                     /translation="MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNP
                     QLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWH
                     DNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD
                     NTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY
                     QKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM
                     KQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSA
                     KNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRM
                     AEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSC
                     AASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV
                     FEPVRKEVKGYVVDPLGKHHFENVSIE"
BASE COUNT         9656 a        11170 c        10323 g         9870 t
ORIGIN      
        1 ttgatcgaca aatccatcaa tttatggacg ttttcgtcgt cccaggtctg gcagaaagtg
       61 gccaggttct gacgagcgtt gccatcaaga tataattcat cattgataat ctgaaatgcg
      121 acatcatcgc gcatttcgtg cagcggaaat cgttttgact ccgcgatagt agaaatggcc
      181 tttgcgccaa aacgtgaatc gagtagttct gagcggaaat ccgttaacag cttctggtcc
      241 atttcgaact ccttaaattt atttgaaggc aataaaaaag taggatttat ccgcaatgga
      301 agcaaggcat tacaggctta atttaaataa caaaatccta agcagaaaaa cgacttttta
      361 taatataaac atttaacatg ataatattaa aaacagactt tattatcgta ataaaaatcg
      421 cccaaacatt gctgttcggg cgatcaaatt aattattgtt tatcctgcat atacggcgtg
      481 tacaccccgt tcagactgtg caggaaagct acgatatcat ccacatcctc ctgcggcagc
      541 tctttgccta cctgatagcg cagcatcagt ttcaccgccc cgtccagcgt cggcacgtca
      601 ccgcgatgga agtacggtgc cgttaaagca acgttacgta aaccgggtac tttctgacgc
      661 aatttatcac gctcttcttt agtcacattc atacgaccaa tatccgccgc cgtaatttcc
      721 ccaaagttaa agtctttttt cagccccaac ggttcaaagg aacgtccgcc gagaataata
      781 ccaccatgac aagttgcaca tttattatct ttaaataatt gatagccttt tttctgttgc
      841 gccgtcagcg cattttcatc tccgcgcaac catttatcaa atggggaatc cggcgtaatt
      901 aatgttttct caaattcagc aatggcatca gtaatatttt cgccactgaa accttgcgga
      961 tagacttcga ggaactgcgt tttaagctgc ggatcttttt ccagcttagc aataatttcg
     1021 tcccaggatt tcgacgccat ttcaatcggg ttcaacggcg gtccaccagc ctgatcctgc
     1081 aatgttgccg cacgaccatc ccagaactgc tcaacgttaa atactgagtt aaataccgtc
     1141 ggcgcgttaa tcggcccaac tgcgccacca acaccaatcg atgtttttct gccatcgacg
     1201 ccccccgcat tcaacgcatg gcaatgagcg catgaaatgg tgctatcagc cgataaacgg
     1261 ggatcgtgat acagcgcaaa acccaacgcc actttttgcg catcggtagg cagtttttgc
     1321 gggatgggct gcaccggttc attgcgatgt tccggagcag tatcattgct ggcgtaatat
     1381 tccgcgcgct gttttgcaat ccaggccagt atttccgccc gctcttcatc actcacctta
     1441 cccgcccagt gtagcgcggt ataacgcgtt ggtggcatag tttcatactg catcacccat
     1501 tcaatcttat tcaaatcgct ttgcgaaacg ggtttatcag ccagcagtgc cgcacgcacg
     1561 gcctcaaggt taaaagattt atatccaagc ttaatgtcgt aatccatcaa ctgtttcgcg
     1621 ccaggaatat aataataggc gggtaattct gccgaaggcg tgtggcaata gtcgcatcct
     1681 ttttcgcgga gaaagcctaa aaccttatta ttttcactga cagcagatgc ctgaacatcg
     1741 gcctgtttac tgcgtttatt atcgtggtac cacacataac cagataaccc taaatagcaa
     1801 atcgcgacgc cagccaggcc gatcgcggta atacgtgaga ccattttcat tattcttccc
     1861 tcacggtggt gagttattgt gacccagaaa attttccaga atgctgcaaa cgtctctgcg
     1921 agacaaagcc atcataaaaa acagggagat acgctttttg ataggaatca atcaattaca
     1981 tgaatataaa ctatcaataa gatagcctgt gcctattacc cagatcagga atggcatatc
     2041 atgattgcgg cgagagcagg attgaatgtt ctgaaaatga aaaacaacac caaatcggta
     2101 tttttataaa ttccattgat attagtgcgt tatatttttt gacaggttaa taaacgtgat
     2161 ccaccgcacg ctttgtcgcc caccaggcgg agcgaatgac tacccttaaa gaaaagccga
     2221 taattagcga cgaatttcgg aggttggatc cttatgctca atcagaaaat tcaaaaccct
     2281 aatccagacg aactgatgat cgaagtcgat ctctgctatg agctggaccc gtatgaatta
     2341 aaactggatg agatgatcga ggcagaaccg gaacccgaga tgattgaagg gctgcctgcc
     2401 tctgatgcgc tgacgcctgc cgatcgctat ctcgaactgt tcgagcatgt tcagtcggcg
     2461 aaaattttcc ccgacagtaa aacctttccc gactgcgcac ctaaaatgga tccgctggat
     2521 atcttaatcc gctaccgtaa agtgcgccgt catcgtgatt ttgacttgcg caagtttgtt
     2581 gaaaaccact tctggctgcc ggaggtctac tccagcgagt atgtatcgga cccgcaaaat
     2641 tccctgaaag agcatatcga ccagctgtgg ccggtgctaa cccgcgaacc acaggatcac
     2701 attccgtggt cttctctgct ggcgctgccg cagtcatata ttgtcccggg cggccgtttt
     2761 agcgaaacct actattggga ttcctatttc accatgctgg ggctggcgga aagtggtcgg
     2821 gaagatttgc tgaaatgcat ggccgataac ttcgcctgga tgatcgaaaa ctacggtcac
     2881 atccccaacg gcaaccgcac ctattatttg agccgctcgc aaccaccggt ttttgcgctg
     2941 atggtggagt tgtttgaaga agatggtgta cgcggtgcgc gccgctatct cgaccacctt
     3001 aaaatggaat atgccttctg gatggacggt gcagaatcgt taatccctaa tcaggcctat
     3061 cgccatgttg tgcggatgcc ggacggatcg ctgctcaacc gttactggga cgatcgcgac
     3121 acgccgcgtg acgaatcctg gcttgaggac gttgaaaccg cgaaacattc tggtcgcccg
     3181 cccaacgagg tgtaccgcga tttacgcgcg ggggcggcct ccggttggga ttactcttcc
     3241 cgttggctgc gtgatactgg tcgtctggcg agcattcgta ccacccagtt catccccatc
     3301 gatctgaatg ccttcctgtt taaactggag agcgccatcg ccaacatctc ggcgctgaaa
     3361 ggcgagaaag agacagaagc actgttccgc cagaaagcca gtgcccgtcg cgatgcggta
     3421 aaccgttacc tctgggatga tgaaaacggc atctaccgcg attacgactg gcgacgcgaa
     3481 caactggcgc tgttttccgc tgccgccatt gtgccactct atgtcggtat ggcgaaccat
     3541 gaacaggccg atcgtctggc aaacgccgtg cgcagtcggt tactgacacc tggcgggatt
     3601 ctggcaagcg agtacgaaac cggtgaacag tgggataaac ccaacggctg ggcaccgtta
     3661 caatggatgg cgattcaggg atttaaaatg tacggcgatg accttctggg tgatgaaatc
     3721 gcgcgaagct ggctgaagac ggtgaatcag ttctatctgg aacagcacaa actgatcgaa
     3781 aaataccata ttgccgatgg tgttccccgc gaaggcggcg gtggcgagta tccgttgcag
     3841 gatgggtttg gctggactaa cggtgtggta cgccgtttaa ttggtttgta cggcgaacca
     3901 taatattttt acagccagcc gctaacttcc tgctggctgt aaaattatcc tcttcaggag
     3961 gagatattta acatcattgc cgcctgggtg cgatttttca cttccagacg gcgatacagg
     4021 gattccagat gcgcttttac cgttccggta ctgatattca gcgctctgcc gatctcctta
     4081 tttgattcgc ccgccgctaa catggttaaa atctcccgct ggcgggcgct taacgatttg
     4141 agatctttaa tgtccttttc cggcgtcgtc cgccagtctc caggcagaaa catcatcccc
     4201 atcgccgcac tatttaccgc caacgcaaat gtctcgacgg ttgaatcacg aggcacaatg
     4261 gccagcacat taaaatggat aacttcctgt aaccaccgtt tattgcaatc cgtcgccgta
     4321 attaacacct taacctcagg aaattgcacc acggtttttt gcagcaacca gtagcaaaac
     4381 tcaccatcct gatcgccatc gagcataact aaggcttcag ggtaactttc cagcttttgc
     4441 cataactcgt ctgcctgact ggccccctga atactcactc ctggaatacg ctgctgtaaa
     4501 ctgattttca ttccatgaat aaatattgac tgcctgtcaa acatgactat ttgcataact
     4561 gaatctccac ctgaatacgt taaaaagact taagtagtgg aagggtatta cccgcgagaa
     4621 aaaataagaa ttcgccattt ggcggtggcc attctacaga gatgacgtgt agaaaatagt
     4681 taccgatata aatagttaca gctaaacgcc tgaaattaca tgtcgagggc actatttaaa
     4741 acaattttga ggatttcctt atattggtgg ttagtacgca tgcaattaaa aatgaaattc
     4801 cgcgaccaca agccaaaata acaaacggca aggagacaaa aataagcaca aatagccaac
     4861 acgtcctctg tacactttaa agggaatcgc tgaaaaatac gctctgttta aggggattca
     4921 cctttctcag aaagctattc cgcccttttc ctgctgagaa atcgccacat tcggcatgac
     4981 aacattgtga aacccggcat tagatgttag aaaaaacaat aaacaatgcg atatgcgcgt
     5041 tactgtttcg ctgtgaacaa caatcggtca aagaaatgga taaaattcac gcaatgcagt
     5101 tgttcatcaa agtcgcggag ctggaaagtt tttcccgcgc agcggatttc tttgctttgc
     5161 caaagggaag tgtttcgcgc cagatacagg cactggaaca tcaacttggc acccagcttc
     5221 tccagcgcac cacgcgacgg gtcaaactca cgccagaagg catgacctat tatcaacgag
     5281 caaaagatgt gttgagtaat ctcagcgaac tggacggtct gtttcaacag gatgccacca
     5341 gtatcagcgg taaattacgc atcgacatcc cgccaggaat cgcgaaaagc ctgttactgc
     5401 cgcgcctgtc ggaatttctc tatctgcatc cgggaattga gctggaactg agtagccatg
     5461 accgtccggt agatattctt catgatggtt ttgattgcgt gatacgcact ggcgcgttac
     5521 cggaagatgg cgttatcgcc cgtcccctcg gcaaactgac catggtcaac tgtgccagtc
     5581 cgcactatct gacgcgcttt ggttatccgc aaagccccga tgatctgact tcacacgcaa
     5641 tagtgcgtta tacaccgcac ctgggtgtac atccgttagg ttttgaggtt gccagcgtta
     5701 atggcgtcca gtggtttaag tctggcggca tgttgacggt aaacagtagc gaaaactatc
     5761 tcaccgccgg tcttgccggt ctggggatta ttcagatccc gcgcattgcc gtgcgcgaag
     5821 ccctgcgtgc cgggcggctt attgaagtat tacctggcta ccgtgccgag ccgctctccc
     5881 tttcgctggt ttatccgcag cgtcgggagc tttcccggcg tgtaaacctg tttatgcagt
     5941 ggctggctgg cgtaatgaaa gagtacctgg actgaccgac tatacttttt aagaatgacc
     6001 acgacagaag gacaaaagag cggatgacgc aggaaaacga gatcaaacgt cccatccagg
     6061 atctggagca cgagccgatt aagccgttgg ataatagcga gaaaggcagc aaagttagcc
     6121 aggcgctgga aaccgtcacc accactgccg aaaaagtcca acgccaaccg gttattgcgc
     6181 acctgattcg cgcgacagaa cgctttaacg atcggctggg taaccagttt ggtgcggcta
     6241 tcacctattt ctcatttttg tcgatgatac caattttgat ggtgtcgttt gccgcagggg
     6301 gctttgtgct ggcctcccat ccgatgttgc tacaggatat cttcgacaaa attctgcaaa
     6361 acatcagcga tccgacgcta gccgccacgt tgaaaaacac catcaacacc gccgttcagc
     6421 agcgtacgac tgtagggctt gtcggcctgg cggtggcact ttattccggc atcaactgga
     6481 tgggtaacct gcgtgaagcg attcgtgccc agtcgcgcga tgtctgggaa cgctcgccgc
     6541 aagatcagga gaagttctgg gtaaaatatc tgcgagattt tatttcgctg attggtttgt
     6601 tgattgcgct gattgtgacg ctttcgatca cctcggttgc cggttcggcg cagcaaatga
     6661 ttattagcgc cctgcacctg aacagcattg agtggctgaa accgacgtgg cgattgattg
     6721 gcctggcgat ttccatcttc gccaactatc tgcttttctt ctggatcttc tggcggttgc
     6781 cgcgccaccg tccgcgcaaa aaagccctga ttcgcggaac atttctggct gctattggtt
     6841 ttgaagtgat taaaatcgtg atgacctaca ccctgccatc gttgatgaaa tccccctctg
     6901 gcgcagcatt tggttccgtg ctggggctga tggcattttt ctacttcttc gcccgtttga
     6961 cgctgttttg cgcggcgtgg attgccaccg ccgaatataa agacgacccg cgaatgccgg
     7021 ggaaaacgca gccttaaaat aggccggatg cggcgtaaac gccttatccg gcatacgatt
     7081 ttattcggcc tggctccccg taggccggat aagatgcgcc agcatcgcat ccggctataa
     7141 tgcgcacata acctcttgaa actcgtcccc agagcctctt cagccatcta tttgggagca
     7201 aacaatttca ttccaactca taaccccagc atataaatcc agttggtaac ttttatttaa
     7261 cctgaaacca gttttatcca ctatttataa aattatgtga agcatttcat agaagaaaaa
     7321 tcactggcct aaacattatc ccctttttgc ctgatttttg accatttccg cgatttgtta
     7381 cacattgaaa tatcactttt gctgtgcgta atatggctat tcgttagcca aaaaataaga
     7441 aaagattatg caagcaacag ccacaacact cgaccacgag caagaataca cgccgatcaa
     7501 ctcgcgtaat aaagtccttg tcgcctctct cattggcaca gccattgagt tcttcgactt
     7561 ttacatttac gccactgcgg ccgttattgt gtttccgcat atcttcttcc cgcagggcga
     7621 tcctacggca gcaacgctac agtcgctcgc caccttcgcc atcgccttcg tcgcgcgccc
     7681 cattggctct gccgtttttg gtcattttgg cgatcgcgtt gggcgtaaag cgacgctggt
     7741 cgcctcgttg ctaacgatgg ggatttcgac cgtggtgatt ggtctgctgc cgggctatgc
     7801 cacgattggt attttcgccc cgctgctgct ggcgctggct cgatttggtc agggtctggg
     7861 cttaggcggt gaatggggcg gcgcggcgct gctggcgact gaaaacgccc caccgcgcaa
     7921 acgtgcactg tatggctcct ttccgcagct gggcgcaccg attggcttct tctttgccaa
     7981 tggcactttc ttgctgcttt cctggctact gaccgacgag cagtttatga gctggggctg
     8041 gcgtgtgcca tttatcttct cggcggtgct ggtcattatc ggcctgtatg ttcgcgtgtc
     8101 gctgcatgag tcgccggtgt ttgagaaagt cgctaaagcg aaaaaacagg tgaagatccc
     8161 gctgggtacg ctgctgacca aacatgttcg cgtaaccgta ctgggtacgt tcattatgct
     8221 ggcaacctat acgctgtttt acatcatgac ggtctactct atgaccttta gtaccgccgc
     8281 cgcgccagtt gggcttggcc tgccgcgtaa cgaagtgttg tggatgttga tgatggcagt
     8341 tattggtttt ggcgtgatgg tgccagtcgc tggattactg gctgatgcct ttggtcgccg
     8401 taaaagcatg gtaatcatca ccacgctgat catcctgttc gcgctgttcg cctttaaccc
     8461 actgctcggt tctggcaacc cgattctggt ttttgccttc ctgctgctgg ggttaagtct
     8521 gatgggtctg accttcgggc caatgggtgc gctgttacca gagctgtttc cgacagaagt
     8581 gcgttacacc ggagcatcgt tctcttacaa cgtagcgtcg attctcgggg cttccgttgc
     8641 gccatatatc gcagcctggt tgcagactaa ctacgggcta ggtgcggtgg ggttatatct
     8701 ggcggcgatg gctggcttga cgttaatcgc cctgctgctg acccatgaga cgcgacatca
     8761 gtcgttgtaa taagagtgaa aagcctgatg cgctacgctt atcaggcctg aatttccata
     8821 caatatattg aattcgcaag gatttgtagg ccggataagg cgttcacgcc gcatccggca
     8881 tgaacaaagc acactttgcc aacaatctaa atctgtttaa ttgccggatg tcagacatcc
     8941 ggcaattatc atcacttctt catctgcgac aaaatcgtcc gacactgatt agcctcccct
     9001 tcggaaggtg agatcagtgc cagtaacgcc gccgccggtg ttaccagcgt tgccagtgcc
     9061 gcagcaacag caccacgggc aatcagcggt ccggctttca ccccagcctg cggattttta
     9121 aacgtccccc gcacatacag cggcgaacgc agtgtgataa tccgaattcc tttactctcc
     9181 ggatcaatag tcaaatccag ctgttccgaa gcaaaacttg ccgtgccggt aacattaatc
     9241 aacgcgttct cagtatcgaa agcaaaaatc tgcgggcgcg ccacgccgtt ggcaatattc
     9301 agattcgccg ccgcgcagtt cacccgcacc tcatcatcac caaatatcgc accgacaatg
     9361 tagttgccga cattcagccc aacaatctcc atcaggttgc ggctcaccag cccgtcattc
     9421 atcaacagtt tcaggttgcc gttactgttg cctaaaagtg ccgccaccga gttaccgcta
     9481 ccgcgtagtt ccgcgtcacc gttcatttcc cccagcgtct tctgcatcag ttccacatcg
     9541 ggcatcagtt ctttcagttt cagtcgacga gcctgaatat ctgcccgccc ctgcatcggc
     9601 tttttatcgc cttccagatg aatattcgcc gcaatgctgc cgcccgccat gccaaatttc
     9661 agcggttgca ggcgcaggtc agcatttttg aggatgatat gagtagaaag atcgctaatc
     9721 ggcaggctac tgccatgctc aatgcgccgc cctttgaagc gaacatcgcc atccataacg
     9781 tcccatttat cggtttcgaa gcggtcataa ggcagcactt tgcccgcagg ctgaacgctt
     9841 ttttcgccct tcttctgttc agaccgtttc gacttttctg cccctttccc ggaatcaacg
     9901 ccaatcaacg gtcccaggtc cgccagccgc aattgccgcg actcgacatc accttccagt
     9961 tttggtcgtg gctttccggt ggtgtagacc agagaaccgt ggatatcgct atcaccaatt
    10021 cgcccattaa aaccgcgata atcaaagacc gacgattttt cagtgtcgat tttcgctacc
    10081 agccgaccat ccgtttcaaa cggcggggta tcgggcagca gaacgcccgt cagttcatag
    10141 agatcaccca gtgaatcgcc agaaaattta agccgtaaat cgacaccgcc catcttcatt
    10201 gggtcattca cgacgccatc aaaagcaaca cgggtgttac cagagcggaa atcagcctgt
    10261 accggaaacg gcgtcccttc gccacgcagc gccagcatac cgcctatttt tcccgtaccc
    10321 gtgagcggtt caccgttata tcgtccctgc gccttcaggc caaaaacgta atcgcccacc
    10381 ttttctttat ccgctttacc tttcgatcca gtaacttcgc tgaacggcag cggcttgcct
    10441 aagggatcaa caaaaatctc cagatccgct ttgcttactt tgtcatcaat ggcgatccgc
    10501 ccttgatcga aaagaatatt atccagccga aacgaccatg ccgacggctt tgcattcgcg
    10561 tctttgttat catcgttggc aagattaaac gtccagttat tgttcttttc agagaggcga
    10621 atcaggcgcg cgtcgggctt tccgagcttg atccacggca gccagaccgt tttggtcagc
    10681 agcgccagcg gggccagcgt tgcctctacg cgtggcaaat gcaccatcgt gacttcggga
    10741 atatccggtg gattgccaag aatgatgtct tccgcgtgta catggggcca cggcacccag
    10801 ctgcgccagc cagtttcttg tttttgccgc tcccacacca cgcccagatc gccacggata
    10861 gcgaacggac gattcaactc cgcagagact ttctggttga tagtcggttt gagtcgattc
    10921 cagtcaaaag ttgcaatcaa aatgatcgcc acgacaatca acaacaagaa agcccctgaa
    10981 atcgcagcgg ttattttgcc tgccttgctc atcgttcgct tcctcatatt cttcctgtgc
    11041 cagtcctaaa gatagtccag ccaggcggaa aatgaggcag cttatagcgc cagaaccgcc
    11101 gtattcagcg tttctatcgg tgccgggcgt gaaagaaacc agccttgtgc ggcgaatgcg
    11161 ggcgagttct gaacatcacg ccactcttcc ggcgtttcta cgccctcgac aatcaccccg
    11221 cgacaatagc gattcattag atgtaaaagc tgagaaaaga gtgtgcgtcc ttccggcgac
    11281 tgacgcagca tcacaaacag ttctcgcgcg attttgatgt agtcataacg cacttcactt
    11341 agcgcagaga aatttgccat cccggtacca aaatcatcca gccacagcgg gccaaattca
    11401 cacatcgagg caaaggttga atctttcggc agacggatat gctccaccag ttcgaaacgc
    11461 agccagggaa gacgctcaat ctggcgcagg atttttggtt gctgacgcag ggcgatgagc
    11521 gtagggccat caatattgac cgatgccagc aggccgtgct ctataaagaa gtcggctttt
    11581 tgcgccagca aatcaatctg ctctttcaca acctccatcc gatggctgac ggtgatttca
    11641 gtaaaatagc gatccggcgg caggcgttgc gaagggttca agggatgcgt gaccaccgtt
    11701 aatagctcca cggccattaa ccgcccgcat gtttgataga tcggctgcca ggtgtaagca
    11761 cgctcacact gcaaccaaaa acgccgttcc tgcaagctct cgatgcttgc ttcagggttg
    11821 cttattcgct ggataacctg ccttatcatc aaagatgtcc tgtgtttaaa agtgatgctg
    11881 cccggactcg acaaagatta tcggcgcgta agggcagaac tttaccgcct ggccggggta
    11941 aatttcctca ctccacaacg gaatctttca ggaatacgtt ctggctcaaa aaaataatgg
    12001 aacactgttt taatatggtt gaccagcaaa ccaccacagc gcaaactaac gctaattttt
    12061 tacagatcag gttcacgact atgtccaaaa agattgccgt gattggcgaa tgcatgattg
    12121 agctttccga gaaaggcgcg gacgttaagc gcggtttcgg cggcgatacc ctgaacactt
    12181 ccgtctatat cgcccgtcag gtcgatcctg cggcattaac cgttcattac gtaacggcgc
    12241 tgggaacgga cagttttagc cagcagatgc tggacgcctg gcacggcgag aacgttgata
    12301 cttccctgac ccaacggatg gaaaaccgtc tgccgggcct ttactacatt gaaaccgaca
    12361 gcaccggcga gcgtacgttc tactactggc ggaacgaagc cgccgccaaa ttctggctgg
    12421 agagtgagca gtctgcggcg atttgcgaag agctggcgaa tttcgattat ctctacctga
    12481 gcgggattag cctggcgatc ttaagcccga ccagccgcga aaagctgctt tccctgctgc
    12541 gcgaatgccg cgccaacggc ggaaaagtga ttttcgacaa taactatcgt ccgcgcctgt
    12601 gggccagcaa agaagagaca cagcaggtgt accaacaaat gctggaatgc acggatatcg
    12661 ccttcctgac gctggacgac gaagacgcgc tgtggggtca acagccggtg gaagacgtca
    12721 ttgcgcgcac ccataacgcg ggcgtgaaag aagtggtggt gaaacgcggg gcggattctt
    12781 gcctggtgtc cattgctggc gaagggttag tggatgttcc ggcggtgaaa ctgccgaaag
    12841 aaaaagtgat cgataccacc gcagctggcg actctttcag tgccggttat ctggcggtac
    12901 gtctgacagg cggcagcgcg gaagacgcgg cgaaacgtgg gcacctgacc gcaagtaccg
    12961 ttattcagta tcgcggcgcg attatcccgc gtgaggcgat gccagcgtaa acgcagcata
    13021 tgcaaaaggc tggataaagt gttacccctc tatccagctc atccataaat acctgatggt
    13081 tgtgctaact catcaccatc aggcattact gtgcaggtgg aatatccgtc acttcaggat
    13141 gtacgtcatc cgtggcgaca gaggtggtcg cagcggcggt agatggggcc atgatttgat
    13201 cccagaccgc ctgcaacgct ttcatgttaa attccggctc gcctttcggc tgcagcagta
    13261 ttaacgccat atcattcgac aactgttgac gcagatcctg atttaacatc tctaccgtca
    13321 ggctattaag gaaatcctgc cgcagtttct gatattgctc cggcgcgata tcgacaacct
    13381 gattttgcaa cgaacgcatc cgctgaccca tcagaatatc ggtatcagct cgtgcatagg
    13441 cggcaaacag tttctgcagc tccagtttct tttgcgccac taacgcattg aactcttctt
    13501 ccggcagacc tttatcgcga accttcgcca gttcacgcgc caccagatta aggttgctgt
    13561 tcagcttgtc gtttggtgat tcgatgttga tggcacactg cgcacgcaga tacagcacac
    13621 ggcagtcaaa tccaagaccg atgtctttgc tgttactggc acttaacgct tgctgaacat
    13681 gccagaacag cgcctcgcgg gccaggtccg cacgccagta gcgcagcagt gcggctgatt
    13741 cacgaatcgg ctgccacggc gtatcccaca tgatagataa ccggtcctga cgcaccgcgt
    13801 cagtcataat actcaccgct tccgcacgca gcggagaaag cgtcggcacc ggagctggcg
    13861 tttcacgttt gcctttcagt tcgccaaacg ttttgtttat ttggtcgaca accgagcgcg
    13921 catccacgtt tcccaccacc agtagcgtca ttgcatccgg ggtgtaccat ttctgataga
    13981 aatctttaat tttttccgct tcaacgggtt gtttcagcgg atcggcagga tcgtgaccta
    14041 acaaggttga ccctttcaga cgatagcgcc accagccctc tttagtatcg gcaggccagg
    14101 ttgccaccat gtcctgactt tgcagcgcgt ggttgatggt ttctggtgtg atggtcaatt
    14161 tgccagtggc atttgccaga taagagagcg cttctttcag caaatcgtta cggttattgg
    14221 gcaaactcag attaaacagc gtggtgtcat aagagacaat taccggcggc atcgggcgtt
    14281 tagggtcgat cccctgctgc cacaatgaac gcgcctgtgc tgcgtcaagg ccaccgcttt
    14341 gcgttagcgc aatacgaggg atggcgtgac tgtaaccgct ctgttgtgta ctttcggcga
    14401 gcgaaccggt attaaccagc aggcgaattt caacacgatc gctgggacgc tggggggtgg
    14461 tcagcacttg ccactgtaaa ccgttggaaa gcgtcccctg ttgccatgct ggatcaggct
    14521 ggagcgcatc tgcctgcaca tagccagcag tggccatcat cagcaaaccg cccgctaaaa
    14581 gtcgaatttt tgtgccctgc atgtgaaccc ctgatcaact atcctggtaa taaaaaaact
    14641 gcccgttgtc ggtcagtcta aatgacgtta aaaacacttc gtgttagacc gcaagaacat
    14701 gaaaatgtca cggaagaagt gaaataaacc tgaactcacc caggtggtaa gttcaggcac
    14761 aggggtcaat tatgcgcaaa cacccgcact cggggaaggg agtgcgggca taagtgatga
    14821 gattaagagg ataattcgtg cgttttgcca tccggcgcac gattattcag cacatcgtcc
    14881 agttttttgt ggtccagttc tttcacccac ttagcaacga caatggtcgc tacgccgtta
    14941 ccgaccaggt tagtcagcgc acgagcttct gacataaagc ggtcgatacc gaggatcagc
    15001 gccagacccg ctaccggcaa atggcccacc gcagagagcg tcgccgccag cacgataaag
    15061 ccactacccg ttacccctgc cgccccttta gaagaaagca gcaacacgat taacagcgtg
    15121 atttggtgga cgatatccat ctgactgtta gtggcctggg cgataaacac cgccgccatt
    15181 gtcaggtata tcgatgtgcc atcaaggtta aacgagtagc ctgtcgggat gaccagcccc
    15241 accaccgatt tacggcagcc gagtttctcc atcttgtcga gcatacgcgg cagcgccgac
    15301 tcggaagatg aagtccccag tacaatcagc agttcttcac ggatgtagcg gataaatttg
    15361 aagatactga aaccagtcgc tttagcgatt gaacccaata ccagcaccac aaacaggata
    15421 caggtaatgt agaaacagat aatcagctgc cccagttgca ccagtgtgcc gacgccgtat
    15481 ttaccgatgg taaacgccat tgccccgaac gcaccaatag gtgccagacg catgatcata
    15541 ttgatgatgc cgaagatgac ctgcgagaaa ctttcgatga cgttaaaaat cagttggcct
    15601 ttgctgccca gacggtggag cgcaaaacca aacagtacgg caaacagcag cacctgcaga
    15661 atgttaccgc tggcaaatgc gccaatgacg ctcgccggga tgacatccat aatgaaggcg
    15721 acaatgccct ggtctttcgc ctgatcggcg taaaccgcta ccgctttcgc atcaagcgtt
    15781 gccggatcga cgttcattcc ggcaccaggc tgcacgacgt taacgatgat aagaccaata
    15841 atcagcgcga tggtactgac aatttcaaag taaagcagtg cgactgcgcc ggtacgaccg
    15901 accgccttca tgctttccat gcccgcaatg cccgttacga cggtacaaaa gatgacagga
    15961 gcgatgatca tcttaatgag cttaacgaag ccgtcgccaa gcggtttcat ttgctcgcct
    16021 atttcaggat agaaatggcc aaggagaata ccaatggcta tcgctgtcag gacctgaaag
    16081 taaaggcttt taaacagaga ggttttcata gggtgtcctt tagtaaaacc acaggtcttg
    16141 taaggttatg gggtacctgc ggccttaaaa taacacccag acaacatcac agaaatgtac
    16201 ctggatcata attgaaacaa aaaggttaaa aagtttgagc tggctcgcac aaaccagcac
    16261 tttttaaagt tttgtaatca gtttggggta gctacttttc ttccaggtaa ctctcttcga
    16321 agatttcaat agggagtggg cgagcaaaaa ggaagccctg ggcaatacca acgcccgctt
    16381 ttgccagcca gtcgcgttgt gcttcagtct ccacgccttc ggcaatcatt tgtaagttca
    16441 ggctctgcgc cagcatgata attgcagcaa tcatgctgct atctcccggc aagccttcaa
    16501 caaacatttt gtcgattttc agtacgtcga ttggcaacga tttcatatgc tgcagctgac
    16561 gcagccctgc gtagcccatg ccgaaatcat ccagcgccac ccgaactccg gcattgcgca
    16621 gcggacggag gattgccacc gcagcatgag ggtcgtcaat acgtcggctt tctgtcactt
    16681 ccagaatcag tgttcccggc tgaatgcgat agcgggttaa cagttccagc atatccgcca
    16741 ccatattcgg gtgcatcagt tgcagcgcag agaggtttac cgacaagggc agcataatgc
    16801 cgcgctcttg ccaggctgca agcaatcgac aggactcttc cagcacccag tgaccgacgg
    16861 taaccatcag cccacagcac tcaatgcgat cgattaagcc atccggcagg tcccaactgc
    16921 catccggttg ctggatacgc agtaacactt ccgcactgac cagtttaccg ctggtcatct
    16981 cgacctgtgg ctgtaaccaa atagcaaact gatgattttc cagtgcatta aggatatcgc
    17041 tctcttccgt caaccgcttc tgggcggctt ccatctgctg cggatcaaag aactgaatct
    17101 gattcttgcc tttatggcga gcggtaaatg ccgcagaaat agcgcgactg taaagctgtt
    17161 cggcggtgag atcgccgtag aacatcgcca cgccaatgct acagtgcgga cggagttgaa
    17221 tacgttcaat cggcaggcgc tcgctcatga tagtgagcac ttgctgacct aaggtgattg
    17281 cgtgccacgg ttcctgtaca ccgttggcaa tgacagcaaa gtcataaccg ctaatctgcg
    17341 cgaggatcat acgtggcgac agtaccgatt tgagtttttc caccagcgtc agcagcagaa
    17401 tttctcgttg cgcctctttc agcacgcccg cagtatcacg cagggtttca caggtgatga
    17461 tcatcagcgc ggtggtttgt ttacgcgcga caacctgctc cagcatctcc atcagcaagg
    17521 ctttgttcgg caaatccgac accgggaagc gcatcgcatt ttcgttctgt tcttcataat
    17581 ggcgctgcag caattgctgg ttgaggttgt aactgcgcac caacataccg atttcatcgt
    17641 cctgatgcag acgcggtaat gccagttggt gaccaacaag ctccttggct gggatggcgt
    17701 taagttcgcg agcaatattg cgtaacggat gcaaaatcag gcggttaatg caccagctga
    17761 tggcgacggt caggataagc gacaaaagta agtaaatggt cactaacgtt gagagggtgc
    17821 tcatcacgaa cttatacata cggaaggaat ccgcctgtag taccagatag gcaattggct
    17881 gcgggtttgc cggacgttcg agcgagtaaa cgcccagcga gatttgaacc ggtagctcaa
    17941 acaggcgagt aaccattacc ggcaccgggc gctctggaat aaaactttta cgcagcgcct
    18001 ggaactggtt aggcagcact acatcggcac ggctgaccac gcctgccggt ttaatgctgg
    18061 caagaatagc ttccgcttcg ggaatatcgc ctttcaaaat agctgaagat aagggttcgc
    18121 ggacagagcg agcaatgctt tccagttgcg tagccgtgtt atagcgattc tgctggacca
    18181 gatggaacag caaaacggtg caaaaaataa aaacgaacac caggacaacg gctgccacca
    18241 ttgccatctg cttgattgtt aacgagcgac ttacgcgcaa attgtctccc cccggaaatc
    18301 ccagattgcc gcccgagtat acccgatcgc agcggcatta agagaggcgc tatctgaaaa
    18361 cttaccagtc ggcgtaaggt atcagcggct gcggcggtaa atccatgtca ccctgccatc
    18421 cggcggcgga ataacgtacg tagagcagga aatggctggg tgcgtaatct ttcgcctgct
    18481 ggatatcaat tgccgtgcca acaaaccagt tggaagtaac acgtcgttca agtaatgccc
    18541 gcgccgtgta gccgaagccc tgactgctgc cgccatcgtt ggattgccgc gcagcttctt
    18601 cctgccagtc ggtcgggatc agattcatca gcggataacg cggcatggtt ttggtgcgtg
    18661 aatgcgacca cgagccagac gcacccagct cccacgacca gttttccgtg cgctcccgcc
    18721 acatcaccgg tatggcaaac gacaggtatt cctgcggact gtagtaaccg ccctgaccga
    18781 gtgagtagcc actcagatct ttgtcgtaat gccagatcat gttgttcagg ccgattgtga
    18841 cgcggcgatt gttctggtta atgaccttat agtaatagcc cgtcatccag cgcacgcgcc
    18901 agttatcttc gacattttta ccggttaact ggtcgccact aagcgatgcc cagacgccgt
    18961 ttgcttcacc tttatcgtag ctcagactta gccccacacc gtcggcacgt acgccacccc
    19021 attttttccc ggtattgctc ggggagtctt tttgcccacc aaaggccagc aaagaactgg
    19081 agatgggccg acggtgggcg ttaacggtgt aacccagcgg cccgatatca tcgctgtaac
    19141 tgatgccgcc gaccacatcc accacgttga agcccatcgg cgtggtaccg atatcccagc
    19201 tccagacgtc atttcgccag ccgaccgcca cgctggcacc ggaatccgac tggctgcggt
    19261 tgccgctaca gtcctgtaat gtacaggtgc cccagttgtc atcccatttg ccatcggcat
    19321 tagtggagaa actgccgacg ttcatattga cgaaatcact gcgaaagaac atccgcccgt
    19381 cagaatacgg cgcatccacc tgcaacatgg tagtgtgcgc tttcagatcg gagtaaccac
    19441 cggtgccgct cgaaccccag taatcgtgct caagggtgac gttaagatcc tgctggcgat
    19501 agaggtccgc cgcatcgctg cgcacgccac gtttcagcca gtcatctttc tcgtcgttac
    19561 gggtcagtcg ggtaaaggtg tcgttatcct gcggacgcgt cgtagtcaca ccggatgcga
    19621 ccatggcgtc tttgtaggtt tccagcgcct gcgttggatc gcccgcctgc gcttcaaact
    19681 tcgcaccatc acgcagcacc atcgcgcttt ccatcgacgg tggctgagat tttgcctgcg
    19741 ggatcaactt attaaacgtc cgctgcgctg ctgcggtatc gccaagctgc gcctgtgcca
    19801 gcgccacgcg ccgctgtgtg ttcagcgagg cgttatcggt agcgggcagt ttcgccagct
    19861 ggctacgtgc cgccgctttg tcaccggcag caatatccac ttccgtcaga ccaagaatgg
    19921 cgtcggcgtt agctggctcc cgcgtcagga cattctgata tgcagcgcgg gcggcggtgt
    19981 aatcacgtcg ttgttgcgcc cagtcagcca gcgtgaggtc aatacgcgtg gaaggtggtt
    20041 gctggcgcag catcgcttcc gcttctgcct ctttgccgct ttctcgcagg cggttagcgg
    20101 tttccagcac ctgatcgctt tgcagtcgat taaccagctc ctgaatattg ctgttccact
    20161 gcgcacgcgg caggctgttg atatgcgcca gcgccgctct gtcctggtca tgaccagaga
    20221 ggtacagccc gtaagcgtaa acctgctccg ggtcgttcga cttctgctgc gccagattgc
    20281 gcattaacgt atcggcctgg ctgcgttgtc cggcctgcca gagatcctgc gaaagtcggt
    20341 aagtaatcca tacgctgccg gggtccagcg ccagtcgttg ccgctgaagt gctgccgcct
    20401 gcgcccattt gccctggttt tccagtgcct ctgcctgctg tgccagacgg tcgttttgca
    20461 ggctgcgttc gatatcatca atgctacgcc gctgactggc agagagcgag gcgataaacg
    20521 cttcagcttt ttctggcgat tgctggcggt aaatatttgc cagcccgcgc acggcgttag
    20581 tgttgccgct gtccatacgc aaggtctgct gataataacg ttcggcggcg ggataatctt
    20641 ttcgcgccat cgccacatcg cccagcccca gcactgcata actgtcggtg ttatcgacat
    20701 tacgcgcctg ctggaacagg cgttctgccc ggtcaggatt attggctttc agcgcagcat
    20761 cgccctgctg gatcgccagc cagtagcggt ttactttcag cagactgttc catttgtcgt
    20821 tgttgctgct gtgcgggtcc agtgcgaggg ctttttccag attcgccact gcattggcgc
    20881 gatcgccttt ctgagaatac gcctggccca gcgcccccag agcttcactg tctttcgggt
    20941 tcgcccgcac cgcctgttgt agttcgggaa tggctttacc cgccatacca gagtccaccg
    21001 ccgctaaacc ttgcgcacga gcgcggaaag caggatcggc cagctgtttt tgctgttctg
    21061 ccagttgcga ttgcgcagcc gccacgctat cgccatcact aaagatcgag agatattttt
    21121 tcagcgccga cacactggca tcactgacgg gcatgtcttt aatctgcccg taccagattt
    21181 tagaggcccc ttcgcgcccg gcgttcgatt ttgccatctg ttccaggacg gcaaaacctt
    21241 cgtcacggcg atcgctacta aacagcaata gcgccagatt gttttgcagg cccgtattgc
    21301 ccggtgcatc cgcattgatg cgttttaact gattaatcgc ttcgccacgg cgagccggaa
    21361 ttttcgccac cgtactccag tactcgacag caatgtcacc ttccggcggc gcaccgttga
    21421 acagtttgtt gtaactcgcc acagcttctt ctgcatgacc ggtcgtcgcc tgcaatcgtg
    21481 cctgttgcag tgcctgacga ccatccggcg tggaaagtag catcgtagtc cgcgacgatt
    21541 tatacgcatt tgaactcggc gctaactgcg acagccgatc gagctgtttt tgcgcgccat
    21601 caatatcgcc ctgacgtaac aaagaacgga aacgggcggc aacgacgtcc gggttattcg
    21661 gatcaataag ttccagccga tataacgact gttgcaccag atcttcacga tgggtcgctt
    21721 cgcctaaccg aacttgctcc agcaactgtt gctgagcggt tggtgctgcc tcgaccatcg
    21781 gcatgacggc cagaccgagg gaaagcgtga atatgtttag tgtgaatttg cgcattcctg
    21841 gccccagtca ggtaataact caccttttgt cgagaagcgg aaacggtgtt gatcccagcc
    21901 ttatccaaac agggtcagca catagttgta ataggcatcg ctgccgggaa agttatcggc
    21961 cacgcgctgg cgctgaacgg cctgcgcatc gcggttttgt aaaaagggca gcatggcggc
    22021 agaaaaaccg actggtcctt taccctgcgc tttccccgta gccacatcca ctttttccgg
    22081 cggataaccg tttttctcag tgaatgtcgc catcggttta aaccggttga gcatccgcgc
    22141 tttttgcgga tcgctgtcag gcatcatgcc tacccacatg taaacgcgga tagcgtcgta
    22201 gctgctgatc aatgtttttt cggcttttag ctgccagcct ttgtctttct catagcgcac
    22261 ccagtctggc gaaaaacctt tcggggcggt ttccagcaat aaacgttgat tggtttcgcg
    22321 cagcgtggtc cacggcgcgc caaagcgggt gaaatactgc gccagcgtcg gcggcaggta
    22381 gctggggtta aaacgccagc tgttatcctc agcaaaaccc actttgcccg gtaacaacat
    22441 ggaacccagc ccaggcaccg tcaccacttc ctcccgcgcg atacgtttta gcaacgcgct
    22501 gccgatgtcg gtataacgct gctctttcca caaacgcccc gcctccagca acgaccaggc
    22561 catccagaca tcaccatcgg aggccgaatt gctgtccagc acttcccact tactgttctc
    22621 tttcttgccc cacagccagg cgggcaaacg ttcttttaaa gaaccctgag cgagattgtt
    22681 ctgcgtccag tcgagaatat tatcgaaagc tgcacggtcg ttagccgcca gggcagagaa
    22741 catgccgtaa ctttgccctt cggaggtggt gattttgcgc gcgtcgctgg ggtcgatgac
    22801 gcgcccttcc tgactgatgt aatccttttt aaactgctcc caggcaggcc aggtacaggc
    22861 tgcctgaaca ctaaaggcag ccagcagcag catcgtcacg attccactac gcaacacatt
    22921 catcttcaat tactcgttat ccgggttaag acgacgacga ctaataattc gcagcagacg
    22981 ccacagtacc catgccagca atatcacact gatagccgcc agcaccgcca gcagaatcgg
    23041 atggtttgcc agcgcatacc acacgcgctc gaaccacggc agatgaccta cgtaataaac
    23101 gtcgccaaca cgtaggctgt tgataccgga ctcgcggatc accgcgaccg aaccgaacat
    23161 ggtggcgcgt ttgccgctat cgttcaccgc atcgttaagc atttcataac cgcgtgggct
    23221 atctgccaac agcgcaatca cgctgcgctg gtcgttatac ggcgactgga agccaatcac
    23281 cgccgccatc gcaccggaag aggtcagcgt tgaccgggtt tctgccgcgc gatcgctctc
    23341 gtccggcaca atgccgggga acggggtctg gcgcatcggt gttttcaccc agctttcggt
    23401 cgcctgcacc aataggtcga tctgcttatc gtctttcagt ttgtccggga taccaccgat
    23461 gatcatgatg tcggcatctt tgccctgaat ggtgctgcca tcatcggtca ccgtcagatt
    23521 aatcgccggg aagcccgtct gtgcgccgat aaaaccaaca gtattcagca acgtttccat
    23581 ctgtgcttcg ttaggcgctt tcggcatcac ggtgatggtt tgcgacagat ccgccatccg
    23641 gctgaatggg aagcccgcgt tagcaaaggc gcgtagatcc ggcatcggga tgaagtggta
    23701 atacttcgag aagtcgatgg tggagtcgtc accaatcacc acatgattct gcaccggctg
    23761 gaaggtaata cagttatcca ccgaaccgcc cggcatcggg ttcatatact caaagtcgaa
    23821 gcgcagctgg ttggtcgcgc ccagtttcag cgccggaata gagacatctg ttttgccatc
    23881 cagcaaacct tgtaataccg gaatccgcag cagcaggcgg ttcgcctcct gtttgctgct
    23941 caggttgaag gattgcagga actggttatt caggctgata tccatccgcg aactgtcttt
    24001 caccggcggc atggtgtagc ggtaattaat atccatatca atgccggtac tgcgcatcag
    24061 gtagagatcc ggcggcaggt ttagcgaaac gttaatcgct gctggctcaa gaccgctgga
    24121 ttgtaactgt tcttcatagg ttttcagttc gccaaatgtg accggacgat cggtacgtac
    24181 ccagttcggc gcatcgtacg gcttacgcgg tagcagcggt ttcacttcat tcactaccac
    24241 gctttcacca cggaacagaa tgttaccctg agcgatacct ttcgctgcct gcaacaggtc
    24301 tttgtcgtca cgaccaaaca ccaccagcag tttgacgtaa ggattctgcg gatggttaat
    24361 catctcaatc accggggctt ttaccgccgg atgatcgcgc aggaagtccg gccgtttgtc
    24421 gttggttgca aagacaatgg cattgcgatc cggcagttgg ttatagagta ccgggaagtt
    24481 ctgcccacgc cagccagaac gcgaaccaaa ccacgaggcg acaatggcag aggcttgttg
    24541 cagcccaaca tccggcgcac ccgcaaagac catcggcaag gtgttggtgc ggttatcgcg
    24601 cgggtcaaag aatggcaccg ggaagtgtga caggtcattc ttcacattca gggtctgata
    24661 ggtcagatcc agtccactgc tccgcccaac atccagccaa agcgtggtgc tggccgggtt
    24721 ttcgcacacg tcctgataat ggccgacaaa ctccagccgt acacggttga agtcggtaat
    24781 aaacagtggg ttaatgggca tttgcgccag cgttttttta cccaactgtt ctttggtcac
    24841 tggcagcacg cccatcagtt catcattgag ataaaccttt aactgcgact ggacaggcag
    24901 taacgatggc gatggggtgt attcgaggtt gagcatcgcc ttcgtcacca cttcatcgct
    24961 gcgcatacca aactcaatgc tgccgttcgg gttaatgcca cgtagcacca tgctgcccgg
    25021 cggcggtgca atttgcgcaa aggtcagctt cacatcacgc gaaggaccgt tctgcgccac
    25081 gactggcgca tcagcgccct gcacgcccgg catcacttgc cccacctgcg gattttgttc
    25141 cgtctgggcg gctacagctg gctcagcatt gatcagtggt tgcgttgctg gcgtcgcctg
    25201 cgtcatgaaa gaggggaacg cactcatccc catagccact gcacaaatcc agaatagttt
    25261 tcttttcatc gcgttatcat cattgttgag ccaaagcctg atccgatggt tgtgccgttt
    25321 cgctccgctc cgggcggcgc ggaataaacg atacaaccca ggaaaccaga gaagtcagca
    25381 cacggaatat gcccttcacc gaagaaggcg caaactccgc cagatggcgg tagccacgga
    25441 agccgagctt cagaatatcc agcagacttt ccagcggctt atcttccggg tagctgtcct
    25501 gccagagcgc ccatgtatcc gcacgggcaa acgtacactg cacaaaatcg atatgttgct
    25561 gggtggtgag cggcattaat ttcagcccaa cttcattacc catcacgcgc gccacctggg
    25621 tcgggaagac gtattcctgc tgaccgcgtt taagcaacag attcactttc tgcccttcca
    25681 gaatctgcgc ctgaccgttg atcttgatcc ccaaaccacc gtcggagaaa tcctgaacgg
    25741 tacacgagaa gaggtgacca tcttcgcggg caattgccgc gggcatcgtc atctccacgc
    25801 ggtgcgatcg gcgtacctgt ttgctttcta ccgataccgc aactgcgccg ccaagaacaa
    25861 tcaggttgta gaacacccac accatactga cgaccacggt gagcatctcg gttggcgggc
    25921 catagaagta gcgccagatg cctaccgcaa cgcccaccag gttgagcagg acaaggaaga
    25981 tgtagggccg cgagatcacc cagtcgacgt actcttcttc caccagtcca cctttggcgg
    26041 tgacgttaaa tttgcctttg tgcgggttaa tcagcgccac cagcgtcggt ggtgcgatat
    26101 accacgccag caccgtttcg tagatttcac tccagaaaga gtggcgatat ttgccctgga
    26161 tcttggagtt ggtcaggctg gcatggatca tatgcggcag cacgaatagg gcgatcatca
    26221 acgctggcgc atagatgatg taggcatgaa gcagcaggaa cgccagcggc gcagtcagga
    26281 agatcagccg tggaatgccc gacaagaagt ggaacatggc gttgacgtaa catagccgct
    26341 gagcaaactt cagcccttta ccggtgagcg ggttatcgag acggaagatt tgtaccatcc
    26401 cgcgcgccca gcgaatacgc tgaccgatat gcgccgacag actttcggtc gccagccccg
    26461 ccgcctgcgg aatacgcata tacgcggagg tatagccacg acggtgcaac cgcagagaag
    26521 tatgcgcatc ttcagtcacg gtttcgacag caatgccgcc aatttcatcc agcggcttac
    26581 gacgaatcac cgcacaggaa ccgcagaaga aagtggcgtc ccacatatcg ttgccatcct
    26641 gcaccagacc atagaacagc gtgccttcgt tcggcgtttt acggaaacgc cccaggttgc
    26701 gttcaaacgg gtccggtgag aagaagtggt gcggcgtctg catcatcgcc agctgttttt
    26761 ctttcaggaa ccagcccatg gtcatttgca agaacgatcg cgttggtacg tggtcgcagt
    26821 cgaaaatcga cacgaactcg cctttggcat atttcagcgc attgttgatg ttgcctgctt
    26881 tcgcatgttc atgagtggtg cgggcgatat atttcacccc cacgttttgc gcaaactggc
    26941 gaaactcttc cctgccgccg tcatcaagga tccagatatt cagcttatct ttcggccagt
    27001 cgatacccag cgaggcgtaa atggtatttt tcaccacgtt gagatcttcg ttgtaagtcg
    27061 ggacaaagat atccaccgac ggccacagcg acatatcttt cggcaatggc accggctgac
    27121 gattcagcgg ccatactacc tggaagtagc cgagcaccag cacaatccac gcgtacgttt
    27181 cagcgaagag cagaataagc ccgcacacca ggctgaccgg atcgtcccag ttcagcgtag
    27241 aggtgtaacg ccaccagata taacggcaag aaacggtcag cgacagcaca atcaacatta
    27301 gcgccgagaa gcgccccggc atccgccgta cgatcagcgc taccccccac agcagcatca
    27361 ggaagataaa ctgcgccagc gggttaaacg gctgagtaac gcagattaac gccagaatca
    27421 gcgagaaggt gacgatgata ccgaggatca accgccgcgc cccggcactc aaatgaccga
    27481 gctctttttt ctcatccaga tgctgtgttt tatggctaac gcgctcaggc agctcgttca
    27541 tccattgatg gtaacgtcca cgaatatttt gcagacctga aaatgcccgc ctgcgcggtt
    27601 tcggcgtttc tttgcgcgat gcaccgatca ataaccagca tgtttgaatg agataacgga
    27661 ccgggtccag cggacgcgga cgcgaggcgt tgatatgcgg atacaggttt ttatgttctg
    27721 cgcgaatacg ctgccagcgc gggtgctcca gcggaataaa aatccaggcc aggatcatcc
    27781 agaaacagcc gagcgtcgcg ctgaaagccg acgcaccgtg acgacgataa tcgcgataac
    27841 gcccgataag ccgcgcgttg accggcggga taagcaacca ccgggtcagg atactcatga
    27901 tgcactcccg actggcgttt tcagcccgga gtagttcaac aggcaccagt tcgccagcgt
    27961 cagtatctct tcagccgcca gcgcatcact gcgatattca cctactggtt gcttagccgc
    28021 caggcattca gccatcgctt catcacgatg aatgagcatc ggcagtaatc ggcgctggct
    28081 ttgcaaccaa agctggtaaa tatcgtcctg aacctgactg ccaatacgga agtcattaat
    28141 caaaatatgt gcgccatccg gcagcgcttg ctgatgcagt cggatatggc agttggcatc
    28201 cacattgacg attgccagcg agtgatcgca caaactcagc agctggtggg ttatctgcga
    28261 ggcatcacgc ggtaagtcga ttaaaatcca ctggtaacgc ccgctggctt ttagttgctg
    28321 taagccggag caaatatcgc tcagccgggt ttgccagtgc tgtggatttt cttgttcttc
    28381 aatggataac tgaccaaaag gcagcaaatc gagctgcgag gtgtagcgca acccagcgtc
    28441 acgtcagtcc tggccatcca gcatcgctct ggcccagccc tgacggtggg taaaatcaac
    28501 attaaatgac aggcgcaaca agttgtccgg gcaggcatcg accaccagga cattttctcc
    28561 caacatttgt aatgaccagg ctaatgcggc ggtgatggtt gttgtcccca cgcctccccg
    28621 caccccctgc aatcccagta cggccattca ccaatcccct acttttgttg cgcaaactct
    28681 gccagcaacg gccagcgttt taatgccgcg gccaactgtt cgcgttggga aatatcggca
    28741 taatcaatat caggcagtga aaatgcctgc tttaacgcca caatatcatt ctggaagata
    28801 tagcctatcg cgggatcagg cagagtatct ggttcattgt tattcatttt gcttgatccc
    28861 tatgaaataa ccgtaccgtt catgagacaa ttctaaccgt gagcatttcg ccggtttatt
    28921 gtttacggcg agacgggaat ttgctcactt tttgactttc cgttacgcaa cagaaaaagt
    28981 taaaaacgaa aagactaaaa tcacacgtct tgtgaccttc taaattgatt cacatgctaa
    29041 atctgataag ttttaatttc aatggtaggt ttatttctta gctttcgcta gtaaactgat
    29101 aatcagacaa aatggtgaca tgagggacat tgtggaccct gtattctcta tcggtatctc
    29161 atcattatgg gatgagctgc gacatatgcc agcaggcggc gtctggtggt ttaacgtcga
    29221 tcgccatgaa gatgctatca gtctggcgaa tcaaacaatt gcatcccagg ctgaaaccgc
    29281 acacgtcgcg gtcattagca tggacagcga tccggcgaaa atctttcaat tagatgattc
    29341 tcaagggccg gaaaaaataa aattattttc aatgctaaat catgaaaaag gtctatacta
    29401 tttgacccgt gatttgcagt gttctattga tccccataat taccttttta ttcttgtttg
    29461 cgcaaataac gcatggcaaa acattcctgc cgagcggctt cgctcatggt tggataaaat
    29521 gaataaatgg agcaggttaa accattgttc gcttttggta attaatcccg gaaataataa
    29581 cgataaacaa ttttcattgt tgcttgagga ataccgttca ctttttggtc ttgccagttt
    29641 gcgttttcag ggtgaccaac atttgctgga tattgccttc tggtgcaacg aaaaaggggt
    29701 cagcgcccgt cagcagctta gcgttcagca acaaaatggt atctggacat tagttcaaag
    29761 cgaagaggcg gagatccaac cacgcagcga cgaaaaacgc attctgagta atgttgctgt
    29821 actggaaggt gcgccgccgc tatcggaaca ctggcaactg ttcaacaata acgaaatcct
    29881 gttcaatgaa gcccgtaccg ctcaggcggc gacggtggtc ttttctttac agcaaaatgc
    29941 gcaaatcgag ccactggccc gcagcattca taccctgcgt cgccagcgcg gtagtgcgat
    30001 gaaaatcctc gtgcgggaaa ataccgctag cctgcgcgcc accgatgaac gtttgttatt
    30061 ggcctgcggt gcaaatatgg ttattccgtg gaatgcgcca ctctcccgtt gtctgacgat
    30121 gatcgaaagc gtgcaagggc agaagtttag tcgctatgtg ccggaagata tcactacctt
    30181 gctgtcaatg acccagccgc tcaaactgcg tggtttccag aagtgggatg tgttctgtaa
    30241 tgccgtcaac aacatgatga ataaccctct attacctgcc cacggtaaag gcgttctggt
    30301 tgccctacgt ccggtaccgg gtatccgcgt tgaacaagcc ctgacgctgt gtcgccctaa
    30361 ccgtaccggc gatatcatga ccattggcgg taatcggctg gtgctgtttc tctcattctg
    30421 tcggattaac gatctggata ccgcgttgaa tcatattttc ccattgccta ctggcgacat
    30481 tttctcaaac cgtatggtct ggtttgaaga tgatcaaatc agtgccgagc tggtgcagat
    30541 gcgcttgctt gccccagaac aatggggcat gccgctgcct ttaacgcaag gttctaaacc
    30601 ggtcatcaat gccgagcacg atggtcgcca ctggcgacga ataccagaac ccatgcgact
    30661 gttagatgat gctgtggagc gctcatcatg atgaccatca gcgatatcat tgaaattatt
    30721 gtcgtttgcg cactgatatt tttcccgctg ggctatctgg cgcggcactc tttgcgacgc
    30781 attcgcgaca ccttacgttt gttctttgct aaacctcgtt atgttaaacc ggccgggacg
    30841 ttacgccgca cggaaaaagc cagggcaacc aaaaaatgac tcaatttacg caaaataccg
    30901 ccatgccttc ttccctctgg caatactggc gcggcctttc cggctggaac ttctattttc
    30961 tggttaagtt cggcctgttg tgggcgggat atcttaactt ccatccgctc ctcaatttgg
    31021 tgtttgccgc gtttctgctg atgccccttc cgcgctacag cctgcatcgc ttgcgccact
    31081 ggattgccct gccgatcggc tttgctttgt tctggcatga cacctggttg cctggcccgg
    31141 aaagcataat gagccagggt tcgcaggtgg cggggttcag taccgattat ttaatcgacc
    31201 atgtcacacg ctttattaac tggcagatga ttggggccat ttttgtttta ttagtggcct
    31261 ggttattcct gtcacaatgg attcgcatta ccgtttttgt ggttgccata ctgctatggc
    31321 tgaacgtact taccctggcg ggaccaagtt tctccttgtg gccagccgga caaccgacga
    31381 ccactgtaac aacgacgggt ggtaacgcag cggcaaccgt tgcggcgacg ggtggcgcac
    31441 cggtagtggg tgatatgccc gcacaaactg caccgccaac aacggcgaac cttaacgcct
    31501 ggctgaataa tttctataac gcggaggcga aacgtaaatc gaccttcccg tcttcgctgc
    31561 ccgctgatgc tcagccattt gaactactgg tgattaacat ctgttcgctt tcctggtcgg
    31621 atatagaagc cgccgggttg atgtcgcatc cactgtggtc gcatttcgat attgagttca
    31681 agaactttaa ctccgccacc tcctacagtg gcccggcggc gatccgttta ctgcgcgcca
    31741 gctgcgggca gacttcgcac actaatctgt atcaaccggc aaataacgac tgctatctgt
    31801 ttgataacct ttcgaaactg ggctttaccc agcacctgat gatgggacat aacggccagt
    31861 tcggcggttt tttgaaagaa gttcgcgaaa atggcggcat gcagagcgaa ttgatggatc
    31921 aaacaaatct gccggttatt ttgctgggct ttgatggttc gccggtttat gacgataccg
    31981 ctgtgcttaa ccgctggctg gacgttaccg aaaaagataa aaacagccgt agtgccacgt
    32041 tctacaacac gcttccactg catgacggca accattatcc gggggtcagc aaaacagcgg
    32101 attacaaagc gcgggcgcag aaattctttg atgaactgga cgccttcttt actgaacttg
    32161 agaaatcggg tcgtaaagtg atggtggtcg tggtgccgga acacggcggc gcgctgaagg
    32221 gcgacagaat gcaggtatct ggcctacgtg atatccctag cccgtctatc accgacgtcc
    32281 ccgttggggt gaaattcttc ggcatgaagg caccgcatca gggggcaccg attgtcatcg
    32341 aacaaccgag cagcttcctg gctatctccg atctggtggt tcgcgttctc gatggcaaga
    32401 ttttcaccga agacaatgtt gactggaaaa aactcaccag tgggttgcca caaacagcac
    32461 cggtctccga gaactcaaat gcagtagtta ttcaatacca ggataaaccg tacgttcgcc
    32521 tgaacggcgg cgactgggtg ccttacccgc agtaagaacg aaaaaggccg cagagtttcc
    32581 cccctgcggc ctggtccggg cgcaaattgc cattacggca gcctgacgcc cgcatgacac
    32641 gttacttccg cttgttcagc cagttcacga tcatactggc aagaatgcca gcaatgaccg
    32701 gagccgctaa atcatgccag aaggccatgc ccagctctgc gaacgtcata tagccgcctg
    32761 tgttgtaatg acaacgtttc gcggctattc ttgagtggtc tagagtcaag attagccccc
    32821 gtggtgttgt caggtgcata cctgcaacgt gcgggggttt tctctctcca gcaaccaatg
    32881 ccaccaggga taaagccccc gcaacattgc gcctcaccgg aacctttccg gcttgccgct
    32941 gattctacga ttgcttttta ctgtcagcac ccggcaatct tcctcattgc gcgatgcctt
    33001 ccagcttaat ttctttattt gcaatagttg cagttcatat ccgggctgac tccagactgg
    33061 tagtgaaatg cgcaattttg tagaattgcg cctcctcgcg acctccccag tgaatctgtt
    33121 gcctcatttt ttacatactg cgtattcgac ttctccacct gttgcgcaag agaaactggg
    33181 tttattcatt tttgcgaggc cgacttcttt ctggacagga ctttatgcag cacaacacac
    33241 tatcgaaaca caatcagaaa ttgccgttta cacgctacga cttcggctgg gttttattat
    33301 gcataggcat ggcgattggt gccggaaccg tgctgatgcc agtacaaatt ggcttgaagg
    33361 gaatttgggt atttattacc gcagcgatca ttgcttatcc tgccacctgg gtagtgcagg
    33421 acatttattt aaaaaccctt tctgaaagcg attcctgtaa tgactacacc gatattatca
    33481 gtcattacct ggggaagaac tggggaattt tcctcggggt tatctacttt ttgatgatta
    33541 tccacgggat ttttatctac tctctctccg tggttttcga cagcgcctcg tacctgaaaa
    33601 ccttcggttt aaccgatgcc gatctttcac aatctctact ttataaagtc gctattttcg
    33661 ccgtactggt ggcgattgcg tctggtggtg aacgattact gtttaagatt tccgggccaa
    33721 tggtggtggt caaagtaggg attattgtcg tgttcggttt tgcgatgatc ccgcactgga
    33781 atttcgccaa tataaccgcc ttcccgcaag cctccgtctt tttccgcgat gtcttgctta
    33841 ccattccatt ttgcttcttt tctgcagtat ttattcaggt acttaaccca atgaatattg
    33901 cctatcgtaa acgggaagcg gataaagtac tggcaacccg gctcgcgctg cgtacccacc
    33961 gaattagtta tatcacgctc atcgcggtga tcctgttttt tgccttttcg tttaccttct
    34021 caattagcca cgaagaagcc gtttctgcct ttgaacaaaa tatctcagca ctggcgctgg
    34081 ccgcgcaggt gatccctggg catatcattc atatcacctc tacggtgctt aatatctttg
    34141 ccgtactgac cgcattcttt ggcatttatc tcggtttcca cgaggccatt aaaggcatta
    34201 ttctcaatct gttaagccga attattgata ccaagaaaat taactcacgc gtgctgactc
    34261 tggcgatctg cgcttttatc gtcattacgt tgacgatttg ggtttcgttt cgtgtatcgg
    34321 tgctggtgtt ctttcagttg ggaagcccgt tatatggtat tgtgtcgtgc ctcattccgt
    34381 ttttcctgat ctataaagtc gcacaactgg aaaaacttcg cggatttaaa gcctggctga
    34441 ttctgctgta cggcattttg ctatgcttgt cgccactgtt gaagctgatt gagtaaaccg
    34501 gagcgcatgg ccccggtttt gtgagttaac gctgcggatt ttcatcctga tcaacagcaa
    34561 aacaagctac cagttgaccg ccgtagtctt ttagctgcgg ctgcaactgg gtgcaggggc
    34621 cgaagcgccg acgacagcgg gcgttgaagg cgcaacccgg cggtggattc agtgggcttg
    34681 gtagttcacc gctgagcttg atgcgctcgc ggcgatcgtc cgggttcagg cgcggcgtcg
    34741 cggaaagtag cgcctgagtg tacggatggc gcgggttatt gaagatttgg tctttcgttc
    34801 ccttctccac gcagcggccc aggtacatca ccatcacttc atcagcaatg tgctccacca
    34861 ccgacaggtc gtgggagata aagacataag acagccccaa ctcctgctgc aaatccatca
    34921 tcagattcag cacctgcgcg cgcactgaaa catccagcgc ggaaaccggt tcatcggcaa
    34981 tcaccacatc cgggtcgagc atcagaccac gggcgatggc gatacgctga cgctgaccgc
    35041 cggagaacat atgcggatag cggtcatagt gctcggtttt caggccgact ttcgccatca
    35101 tcgacagggc tttttcccga cgctgttctt tgcttaagct ggtgttgatc agcagcggct
    35161 cttcaagaat ttgcccgact tttttacgcg gattcagcga accgtaaggg ttctggaaga
    35221 cgatctggat tttctgccga cgcagcttct gcgcctgcgg atcgtgctta agcagatcct
    35281 gcccctggta atacagctcg ccaccggtgg gcatttcaat catcgtcagc aaccgaccga
    35341 gggtcgattt accgcagcca gattcgccca ctactgccag cgttttgcca cgttcaaggt
    35401 taaacgaaac gccatccagc gctttaacca gacgttccgg cgcgaacatg cctttcttca
    35461 ccggataatg ttttttcagg tcgatagcct gcaacagcgg ttgttgcagg gtggcctctt
    35521 gcgtactcat agtgtcggcc tcccggcatc atcaagtggg taatggcatt tggactgacg
    35581 cccgtcagcg agcatattca gcgccggttc ttcagcgcga catctgtcag tggcataggg
    35641 gcagcgcggg ttaagcaggc agccgttcgg gcggtcgtac ttgccgggaa cgacacctgg
    35701 caacgacgcc agacgttctt tgtcctgagc aaattctggc agcgcacgca gcaatgcctg
    35761 agtatacggg tgacgcggcg catggaagat ggcgtgcgca tcaccggttt ccaccacctg
    35821 gcctgcatac atcacgatga ttttatgtgc cgcttccgcc accagcgcca ggtcatgggt
    35881 aattaacacc agcgccatgt tctctttctg ctgtagctcc agcagtagtt cgatgatttg
    35941 cgcctgaatg gtcacgtcca gcgcggtggt cggttcatcg gcaatcagca gttttggccg
    36001 acaggcaatc gccatggcga tcatcacgcg ctggctcatg ccgccggaaa gctgatgcgg
    36061 gtaaacatcc agacgcgatg ccggatcggg aataccgacc tgattcagca ggtcaatcgc
    36121 tcgctgacgg cgggtacttt tgttgccgcc ctgatgcacc ttaatcgctt ccataatctg
    36181 gaaacccacg gtgtagcacg ggttaaggct ggtcatcggg tcctggaaga tcatcgccac
    36241 ttcggcaccc accaggttgc ggcgctcttt ttctgagata cgctgcaaat cctggccgtt
    36301 aaactccagt ttttctgcca ttacgcggcc cggataatca atcagcccca taatcgccag
    36361 tgaactgacc gacttaccgg agccggactc acccacaatc ccgaccactt cgccctgttt
    36421 tacgctgtag ctgatgcggt ctacggcgcg gaacggcgcg ctttcgtcgc cgaaatgcac
    36481 cgataattta tctacattta ataacgccat ctcgaacctc ttactgcttc agtttgggat
    36541 cgagcgcgtc acgcagaccg tcacccatca ggttaaatgc cagcaccgtc agcaggatcg
    36601 ccagacccgg gaaggtcacg acccaccagg cgctttgcgc gaactgcaac acgtcggaga
    36661 gcatggtgcc ccactcaggc gttggcggct gtgcccccat gccgaggaaa ccaagagcag
    36721 ccatatcgag aatggcgtta gagaaaccga gcgacgcctg aacaatcagc ggcgcaaggc
    36781 agttcgggaa gatgttaata aacatctgac gcatcgcccc ggcacccgcc acgcgagacg
    36841 cggtgacgta atcgcggtta acttccacca gcacggcggc gcgggttaag cgcacatagt
    36901 gcggcaaggc aacgaaggtc agtgccagcg cggcgttacc aatcgacggg ccgaaaattg
    36961 ccaccagcac cagcgccagc agcagacttg gcagcgccag catgatatcg accacgcgca
    37021 taatgatgtt atcgaccagg ccgccaaagt aaccggcgat caggccgaga ataacgccca
    37081 taatcagcga taacacaact accagacagc caaccagcag cgacaggcgc gcaccgtaca
    37141 tcaggcgcga cagcacatca cggcctacgt catcggtgcc cagcaagtgc gccatgctgc
    37201 cgccttcctg ccaggctggc ggggcgagca gtgcatcgcg gaactgttcc gccgggttat
    37261 agggtgcaat ccagttggca aagatcgcga tgaacagcac gatgacgacg taaaccagcc
    37321 cgacgaccgc gcctttgttg cgtttaaaat agtgccagaa ctcctgtaac ggggtcatcg
    37381 gcaccggtgc gctaatcact ttattttcag taacctgtga catgatgtcc ccttacttct
    37441 tatgacgaat acgcgggttc accacgccgt acagcagatc gaccagcaag ttgacgagga
    37501 taatcatcgt cgccaccagc aatacgccgc cctgcactac cggatagtcg cggcgttgca
    37561 gtgcgtcaat caaccagcgt cccagaccgg gccacgagaa gatggtttcg gtcagaatcg
    37621 cccccgccag caatgttccc acctgcaggc cgataacggt caccaccggc agcatcgcgt
    37681 tacgcagcgc atggacgata atcacccgca tgcgggttag ccctttggcg cgcgcggtgc
    37741 ggatgtaatc ctcgcccagc acttccagca tcgaggagcg tgtcatacgc acaatgaccg
    37801 ccagcggaat agtacccagc acaatggcag gcaagatcat atgggcgacg gcatcgataa
    37861 agttgccgtc ttcaccccag atggcggtgt cgattagcat aaaaccggtt aacggattgg
    37921 agtcatcgag gaacaccata tcgctcacgc gaccggagac gggcgtcagg ttccagtgca
    37981 ccgaaaccag catgatcagc atcatgcccc accagaagat aggcattgaa taacctgtca
    38041 gcgccaggcc aaccgctgtg tgatcgaaaa tggaaccgcg tttaaccgca gccagcacgc
    38101 cgaccggaat accgactgcc gtagcaaaaa tcatcgcgca gacgccaagt tccagcgtgg
    38161 cctggaagcg cggcacgaac tcttcccaaa ccgggatgcg gcttttcatt gaaatgccta
    38221 gatcgccatg cataacgccc caaatgtaat ggagatactg ctgccacatc ggtttatcta
    38281 agccgagttc agccagcagc tgcgcgtgac gctctgggga gatcccacgt tcgcccgcca
    38341 tgatcatcac cggatcgccc gggatcatgt ggacaaaggc aaatgtgaga agggtaatac
    38401 cgataaacgt ggggatgacg agtcccaaac gtcggagaat aaactgcaac ataacccgga
    38461 ttctctatag tgacccgcag cctggaactg cgtgtctgta ttgctcacaa atcaattccc
    38521 gcccttatcg gacagggaat gaagtattgc tgccggatgg cgctgcacgc agaggcacag
    38581 cgccaccggg tatacagatt gttgacaaag tgcgctttgt ttatgccgga tgcggcgtta
    38641 acgccttatc cggcctacaa aatcgtgcaa attcaataca ttgcagaatt ttcgtaggcc
    38701 tgataagcgg agcgcatcag gcatttttgc ctttgccatc agtcttgtat ggcttttaat
    38761 tattcgatag agacgttttc gaagtgatgt ttgcctaatg gatcaaccac atagccttta
    38821 acttctttac gtaccggttc aaacacggtg gagtgagcga tgatcagtgc cggagcctga
    38881 tcgtgcatca ccacctgcgc ttgtttgtac agttcaacgc gtttattgtg gtcgtcggta
    38941 gcacgcgccg gttgaatcag atcttcaaac ggtttgtagc accattttga gtagttggag
    39001 ccttgttcag aggcggcgca gctgaacagg gtggcgaaga agttatccgg atccccgtta
    39061 tcgccagtcc agcccatcat taccgtctgg tgctcgccat ctttcgcacg cttgaggtac
    39121 tcaccccatt cgtaggtgac aattttggcc tgcacgccga ctttcgccca gtctgcctga
    39181 atcatctccg ccatgcggcg agcgttcggg ttatacggac gttgtaccgg catcgcccac
    39241 aggtcgatgg agaaaccttt ttccagaccc gcttctttca gcaaggcttt cgctttttca
    39301 ggatcgtagg tgtagtcctg aacgtcgtcg ttatagcccc acatggttgg cgggatcagg
    39361 tttttcgctg atacgcccgc gccctgataa accgctttga tgatcgcgtc tttgttcacc
    39421 gcgtaggtca gagcctggcg aactttcacg tcatcgagtg gttttttctg cacgttatac
    39481 gagagataac cgacgttcag ccccggcatt tccatcagat tgatggattt atcctgcttc
    39541 atgcgagcga tatctgccgg gttcgggtac ggcatcacct ggcattcatt cttctgcaat
    39601 ttcgcgtaac gcacggaagc gtcaggggta atagagaaaa ccagcgtatc gatctgcggt
    39661 ttggtgcccc agtagccatc aaacgctttg tagcggatac gggaatcttt ttgatactgc
    39721 tgtaactgga acggaccggt tccgattggg ttgaggtcca gtttttccgg tgtaccggct
    39781 ttcatcatcg catcagcata ttcttttgac agaatagagg cgaagtccat tgccaggtca
    39841 gcgaggaacg gcgcttccgg gcgagtcagc acaaactgaa cggtgttgtc gtccaccttt
    39901 ttcacttcac tgatcagctc tggcaagccc atgccttcga agtattcgta gctgccgcca
    39961 gaaactttat ggtacgggtt ttgcgcgttt ttctgacgat cgaacgagaa caccacatca
    40021 tcggcgttca gttcacgcgt cggtttgaat tctttattgt cgtgccactt cacaccttta
    40081 cgcagatgga aggtataggt tttaccgtct tcgctgactt cccacttttc agcgaggccc
    40141 gggatcactt cggtggtgcc gattttaaat tcaaccagac ggttataaag cgggacggaa
    40201 gaggcgtcat aggtggtgcc ggaggtaaac agctgcgggt taaacccttc cggagatcct
    40261 tctgagcaat aaaccagagt tttagcctga acacttgctg cgacggtcat agccaccagg
    40321 ctgagaccaa gcttcagcat ccctgacttt ttcaaggaaa tacgcattat tctgctccaa
    40381 ttgtgatgtt tgttgtttta accctttgca gtgggttgtc gttgcctgac cttttttgtt
    40441 ttttgcccgg tcgggtcaac gttatgaggt ggggatgccg tactaattaa catcagtgta
    40501 acagtgcgga tcctccataa aatgcccctc gtgacctaca atctgtcaac agaatgtgaa
    40561 aacgtcaata cagccaaccg ggatttacac caacggtgag aatccacaaa caaagattaa
    40621 aaaaacttca aacagctatt tgcagcagag aaatttgtgc tactccaaca tgaccagaac
    40681 aatcagctta atatttagca acatttggtg attaagtttt atgcatttaa tgaaaaaaat
    40741 ctgaggaaaa ggtggatatc tgagcgatta ataccatgaa cgctaaaacg cacagcggaa
    40801 aatgccaggg ccagccataa gtaacgcaaa aaaagattta agcaaatata aaaaaagaca
    40861 atggtttctg tcacaaatcc gttaatggat agtgagatat ggggcgcaaa tttggcaggg
    40921 aaatgtgtgt cgtgtaggtc gaataaggcg gtcgcgccgc atccgacaat ggccggcaca
    40981 tttgcctgat gcgacgctga cgcgtcttat caggcctac
//
LOCUS       DACAOP010000033        40992 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.033, whole genome shotgun sequence.
ACCESSION   DACAOP010000033 DACAOP010000000
VERSION     DACAOP010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40992
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.033"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            241..795
                     /locus_tag="IT892_001933"
     CDS             241..795
                     /locus_tag="IT892_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417738.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAP3135156.1"
                     /translation="MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVV
                     IRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGN
                     RVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAG
                     LRYSANNYVKWKDEYLDQGNQTQP"
     gene            complement(771..1028)
                     /locus_tag="IT892_001934"
     CDS             complement(771..1028)
                     /locus_tag="IT892_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1488 domain-containing protein"
                     /protein_id="HAP3135157.1"
                     /translation="MNQAIQFPDREEWDENKKCVCFPALVNGMQLTCAISGESLAYRF
                     TGDTPEQWLASFRQHRWDLEEEAENLIQEQSEDDQGWVWLP"
     gene            complement(1025..1843)
                     /gene="aroE"
                     /locus_tag="IT892_001935"
     CDS             complement(1025..1843)
                     /gene="aroE"
                     /locus_tag="IT892_001935"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAP3135158.1"
                     /translation="METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFI
                     NTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLMRLEDGRLLGDNTD
                     GVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAK
                     LFAHTGSIQALSMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKG
                     KTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA"
     gene            complement(1848..2420)
                     /gene="tsaC"
                     /locus_tag="IT892_001936"
     CDS             complement(1848..2420)
                     /gene="tsaC"
                     /locus_tag="IT892_001936"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase type 1
                     TsaC"
                     /protein_id="HAP3135159.1"
                     /translation="MNNNLQRDAIAAAIDVLNEERVIAYPTEAVFGVGCDPDSETAVM
                     RLLELKQRPVDKGLILIAANYEQLKPYIDDTMLTDVQRETIFSRWPGPVTFVFPAPAT
                     TPRWLTGRFDSLAVRVTDHPLVVALCQAYGKPLVSTSANLSGLPPCRTVDEVRAQFGA
                     AFPVVPGETGGRLNPSEIRDALTGELFRQG"
     gene            complement(2425..2967)
                     /locus_tag="IT892_001937"
     CDS             complement(2425..2967)
                     /locus_tag="IT892_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135160.1"
                     /translation="MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACDYV
                     RPLKSSADGHIVKVLEGQVCPACGANLVLRQGRFGMFIGCINYPECEHTELIDKPDET
                     AITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKT
                     AQGVKHFCASKQCGKPVSAE"
     gene            complement(2996..3469)
                     /locus_tag="IT892_001938"
     CDS             complement(2996..3469)
                     /locus_tag="IT892_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 domain-containing protein"
                     /protein_id="HAP3135161.1"
                     /translation="MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFEREDIYNAL
                     LWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLET
                     REMVIERVLALDNAEFELDDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH"
     gene            complement(3441..4565)
                     /gene="dprA"
                     /locus_tag="IT892_001939"
     CDS             complement(3441..4565)
                     /gene="dprA"
                     /locus_tag="IT892_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAP3135162.1"
                     /translation="MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGL
                     TLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSEFYPPQLLATTDYPGALFVEGEL
                     HALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
                     GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGL
                     SKGVLVVEAALRSGSLVTARCALEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEP
                     EEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDEVTPVDVVAERAGQP
                     VPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV"
     gene            4695..5204
                     /gene="def"
                     /locus_tag="IT892_001940"
     CDS             4695..5204
                     /gene="def"
                     /locus_tag="IT892_001940"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP3135163.1"
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEG
                     IGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVP
                     RAEKVKICALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVE
                     KLDRLKARA"
     gene            5219..6166
                     /gene="fmt"
                     /locus_tag="IT892_001941"
     CDS             5219..6166
                     /gene="fmt"
                     /locus_tag="IT892_001941"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAP3135164.1"
                     /translation="MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRG
                     KKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVAELQADVMVVVAYGLILPKAVLEM
                     PRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPIT
                     AEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWS
                     LSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVA
                     TGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV"
     gene            6212..7501
                     /gene="rsmB"
                     /locus_tag="IT892_001942"
     CDS             6212..7501
                     /gene="rsmB"
                     /locus_tag="IT892_001942"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAP3135165.1"
                     /translation="MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALL
                     QELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAET
                     VEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQ
                     WQSIVEANNQRPPMWLRINRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVH
                     ALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAV
                     DIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRH
                     PDIKWLRRDRDIPELAQLQSEILDAIWPHLKTGGTLVYATCSVLPEENSLQIKAFLQR
                     TADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK"
     gene            7523..8899
                     /gene="trkA"
                     /locus_tag="IT892_001943"
     CDS             7523..8899
                     /gene="trkA"
                     /locus_tag="IT892_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HAP3135166.1"
                     /translation="MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFD
                     LRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSP
                     DYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
                     YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHI
                     RAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQN
                     TIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRA
                     YVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTS
                     RVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERL
                     FQPSPFFL"
     gene            9029..9439
                     /gene="mscL"
                     /locus_tag="IT892_001944"
     CDS             9029..9439
                     /gene="mscL"
                     /locus_tag="IT892_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAP3135167.1"
                     /translation="MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP
                     LGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL
                     NRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS"
     gene            complement(9436..9654)
                     /locus_tag="IT892_001945"
     CDS             complement(9436..9654)
                     /locus_tag="IT892_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor A"
                     /protein_id="HAP3135168.1"
                     /translation="MSRYQHTKGQIKDNAIEALLHDPLFRQRVEKNKKGKGSYMRKGK
                     HGNRGNWEASGKKVNHFFTTGLLLSGAC"
     gene            complement(9710..10135)
                     /gene="zntR"
                     /locus_tag="IT892_001946"
     CDS             complement(9710..10135)
                     /gene="zntR"
                     /locus_tag="IT892_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(2+)-responsive transcriptional regulator"
                     /protein_id="HAP3135169.1"
                     /translation="MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESD
                     LQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQS
                     MQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC"
     gene            complement(10146..10514)
                     /locus_tag="IT892_001947"
     CDS             complement(10146..10514)
                     /locus_tag="IT892_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HAP3135170.1"
                     /translation="MWLLDQWAERHIAEAQAKGEFDNLAGSGEPLILDDDSHVPPELR
                     AGYRLLKNAGCLPPELEQRREAIQLLDILKGIRHDDPQYQEVSRRLSLLELKLRQAGL
                     STDFLRGDYADKLLDKINDN"
     gene            complement(10621..11004)
                     /gene="rplQ"
                     /locus_tag="IT892_001948"
     CDS             complement(10621..11004)
                     /gene="rplQ"
                     /locus_tag="IT892_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAP3135171.1"
                     /translation="MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKEL
                     RRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGF
                     RAGDNAPMAYIELVDRSEKAEAAAE"
     gene            complement(11045..12034)
                     /gene="rpoA"
                     /locus_tag="IT892_001949"
     CDS             complement(11045..12034)
                     /gene="rpoA"
                     /locus_tag="IT892_001949"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAP3135172.1"
                     /translation="MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALR
                     RILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTL
                     NKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
                     SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIR
                     RAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIH
                     YIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE"
     gene            complement(12060..12680)
                     /gene="rpsD"
                     /locus_tag="IT892_001950"
     CDS             complement(12060..12680)
                     /gene="rpsD"
                     /locus_tag="IT892_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAP3135173.1"
                     /translation="MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGAR
                     KPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVV
                     YRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
                     LAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK"
     gene            complement(12714..13103)
                     /gene="rpsK"
                     /locus_tag="IT892_001951"
     CDS             complement(12714..13103)
                     /gene="rpsK"
                     /locus_tag="IT892_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAP3135174.1"
                     /translation="MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGW
                     ATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNA
                     AGFRITNITDVTPIPHNGCRPPKKRRV"
     gene            complement(13120..13476)
                     /gene="rpsM"
                     /locus_tag="IT892_001952"
     CDS             complement(13120..13476)
                     /gene="rpsM"
                     /locus_tag="IT892_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018356918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAP3135175.1"
                     /translation="MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVK
                     ISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRT
                     KTNARTRKGPRKPIKK"
     gene            complement(13623..13739)
                     /gene="rpmJ"
                     /locus_tag="IT892_001953"
     CDS             complement(13623..13739)
                     /gene="rpmJ"
                     /locus_tag="IT892_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAP3135176.1"
                     /translation="MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG"
     gene            complement(13771..15102)
                     /gene="secY"
                     /locus_tag="IT892_001954"
     CDS             complement(13771..15102)
                     /gene="secY"
                     /locus_tag="IT892_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004868351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAP3135177.1"
                     /translation="MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGI
                     DAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTL
                     AEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
                     VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFL
                     VLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIP
                     AIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTA
                     LVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMR
                     DAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR"
     gene            complement(15110..15544)
                     /gene="rplO"
                     /locus_tag="IT892_001955"
     CDS             complement(15110..15544)
                     /gene="rplO"
                     /locus_tag="IT892_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAP3135178.1"
                     /translation="MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGG
                     GVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEIRLSDLAKVEGGVVDLNTLKAANIIG
                     IQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE"
     gene            complement(15548..15727)
                     /gene="rpmD"
                     /locus_tag="IT892_001956"
     CDS             complement(15548..15727)
                     /gene="rpmD"
                     /locus_tag="IT892_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAP3135179.1"
                     /translation="MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAI
                     RGMINAVSFMVKVEE"
     gene            complement(15731..16234)
                     /gene="rpsE"
                     /locus_tag="IT892_001957"
     CDS             complement(15731..16234)
                     /gene="rpsE"
                     /locus_tag="IT892_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004106339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAP3135180.1"
                     /translation="MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNG
                     RVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEG
                     TGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKS
                     VEEILGK"
     gene            complement(16249..16602)
                     /gene="rplR"
                     /locus_tag="IT892_001958"
     CDS             complement(16249..16602)
                     /gene="rplR"
                     /locus_tag="IT892_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAP3135181.1"
                     /translation="MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNG
                     SEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGR
                     VQALADAAREAGLQF"
     gene            complement(16612..17145)
                     /gene="rplF"
                     /locus_tag="IT892_001959"
     CDS             complement(16612..17145)
                     /gene="rplF"
                     /locus_tag="IT892_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAP3135182.1"
                     /translation="MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVK
                     HADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNV
                     INLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGK
                     GVRYADEVVRTKEAKKK"
     gene            complement(17158..17550)
                     /gene="rpsH"
                     /locus_tag="IT892_001960"
     CDS             complement(17158..17550)
                     /gene="rpsH"
                     /locus_tag="IT892_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAP3135183.1"
                     /translation="MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEG
                     FIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIA
                     VVSTSKGVMTDRAARQAGLGGEIICYVA"
     gene            complement(17584..17889)
                     /gene="rpsN"
                     /locus_tag="IT892_001961"
     CDS             complement(17584..17889)
                     /gene="rpsN"
                     /locus_tag="IT892_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP3135184.1"
                     /translation="MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNA
                     VLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW"
     gene            complement(17904..18443)
                     /gene="rplE"
                     /locus_tag="IT892_001962"
     CDS             complement(17904..18443)
                     /gene="rplE"
                     /locus_tag="IT892_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAP3135185.1"
                     /translation="MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAI
                     ADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFER
                     LITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTA
                     KSDEEGRALLAAFDFPFRK"
     gene            complement(18458..18772)
                     /gene="rplX"
                     /locus_tag="IT892_001963"
     CDS             complement(18458..18772)
                     /gene="rplX"
                     /locus_tag="IT892_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAP3135186.1"
                     /translation="MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKK
                     HQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSET
                     IK"
     gene            complement(18783..19154)
                     /gene="rplN"
                     /locus_tag="IT892_001964"
     CDS             complement(18783..19154)
                     /gene="rplN"
                     /locus_tag="IT892_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013975775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAP3135187.1"
                     /translation="MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIK
                     EAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGP
                     VTRELRSEKFMKIISLAPEVL"
     gene            complement(19319..19573)
                     /gene="rpsQ"
                     /locus_tag="IT892_001965"
     CDS             complement(19319..19573)
                     /gene="rpsQ"
                     /locus_tag="IT892_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAP3135188.1"
                     /translation="MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKL
                     HVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL"
     gene            complement(19573..19764)
                     /gene="rpmC"
                     /locus_tag="IT892_001966"
     CDS             complement(19573..19764)
                     /gene="rpmC"
                     /locus_tag="IT892_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAP3135189.1"
                     /translation="MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLK
                     QVRRDVARVKTLLNEKAGA"
     gene            complement(19764..20174)
                     /gene="rplP"
                     /locus_tag="IT892_001967"
     CDS             complement(19764..20174)
                     /gene="rplP"
                     /locus_tag="IT892_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAP3135190.1"
                     /translation="MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTAR
                     QIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVL
                     YEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM"
     gene            complement(20187..20888)
                     /gene="rpsC"
                     /locus_tag="IT892_001968"
     CDS             complement(20187..20888)
                     /gene="rpsC"
                     /locus_tag="IT892_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAP3135191.1"
                     /translation="MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLT
                     KELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQIN
                     IAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGA
                     EIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPE
                     KPAAQPKKQQRKGRK"
     gene            complement(20906..21238)
                     /gene="rplV"
                     /locus_tag="IT892_001969"
     CDS             complement(20906..21238)
                     /gene="rplV"
                     /locus_tag="IT892_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAP3135192.1"
                     /translation="METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAA
                     VLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSH
                     ITVVVSDR"
     gene            complement(21253..21531)
                     /gene="rpsS"
                     /locus_tag="IT892_001970"
     CDS             complement(21253..21531)
                     /gene="rpsS"
                     /locus_tag="IT892_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAP3135193.1"
                     /translation="MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNM
                     IGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK"
     gene            complement(21548..22369)
                     /gene="rplB"
                     /locus_tag="IT892_001971"
     CDS             complement(21548..22369)
                     /gene="rplB"
                     /locus_tag="IT892_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAP3135194.1"
                     /translation="MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRN
                     NNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERR
                     YILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGT
                     YVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRP
                     TVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK"
     gene            complement(22387..22689)
                     /gene="rplW"
                     /locus_tag="IT892_001972"
     CDS             complement(22387..22689)
                     /gene="rplW"
                     /locus_tag="IT892_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAP3135195.1"
                     /translation="MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIK
                     AAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE"
     gene            complement(22686..23291)
                     /gene="rplD"
                     /locus_tag="IT892_001973"
     CDS             complement(22686..23291)
                     /gene="rplD"
                     /locus_tag="IT892_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010304939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAP3135196.1"
                     /translation="MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTR
                     AQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYR
                     GALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLA
                     ARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA"
     gene            complement(23302..23931)
                     /gene="rplC"
                     /locus_tag="IT892_001974"
     CDS             complement(23302..23931)
                     /gene="rplC"
                     /locus_tag="IT892_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAP3135197.1"
                     /translation="MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDG
                     YRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFA
                     DVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKK
                     MAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA"
     gene            complement(23964..24275)
                     /gene="rpsJ"
                     /locus_tag="IT892_001975"
     CDS             complement(23964..24275)
                     /gene="rpsJ"
                     /locus_tag="IT892_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014268624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAP3135198.1"
                     /translation="MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPT
                     RKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
                     G"
     gene            complement(24513..24932)
                     /gene="gspB"
                     /locus_tag="IT892_001976"
     CDS             complement(24513..24932)
                     /gene="gspB"
                     /locus_tag="IT892_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative general secretion pathway protein GspB"
                     /protein_id="HAP3135199.1"
                     /translation="MFEFYIAAREQKETGHPGIFSRQKHSTIIYVICLLLICLWFAGM
                     VLVGGYARQLWVLWIVKAEVTVEAETPAFKQSTQHYFFKKQPLPVVESVEEEDDPGVA
                     VENAPSSSEDEENTVEESEEKAGLRERVKNALNELER"
     gene            complement(24934..26403)
                     /gene="gspA"
                     /locus_tag="IT892_001977"
     CDS             complement(24934..26403)
                     /gene="gspA"
                     /locus_tag="IT892_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspA"
                     /protein_id="HAP3135200.1"
                     /translation="MSTRREVILSWLCEKRQTWRLCYLLGEAGSGKTWLAQQLQKDKH
                     RRVITLSLVVSWQGKAAWIVTDDNAAEQGCRDSAWTRDEMAGQLLHALHRTDSRCPLI
                     IIENAHLNHRRILDDLQRAISLIPDGQFLLIGRPDRKVERDFKKQGIELVSIGRLTEH
                     ELKASILEGQNIDQPDLLLTARVLKRIALLCRGDRRKLALAGETIRLLQQAEQTSVFT
                     AKQWRMIYRILGDNRPRKMQLAVVMSGTIIALTCGWLLLSSFTATLPVPAWLIPVTPV
                     VKQDMTKDIAHVVMRDSEALSVLYGVWGYEVPADSAWCDQAVRAGLACKSGNASLQTL
                     VDQNLPWIASLKVGDKKLPVVVVRVGEASVDVLVGQQTWTLTHKWFESVWTGDYLLLW
                     KMSPEGESTITRDSSEEEILWLETMLNRALHISTEPSAEWRPLLVEKIKQFQKSHHLK
                     TDGVVGFSTLVHLWQVAGESAYLYRDEANISPETTVKGK"
     gene            26583..27398
                     /gene="gspC"
                     /locus_tag="IT892_001978"
     CDS             26583..27398
                     /gene="gspC"
                     /locus_tag="IT892_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspC"
                     /protein_id="HAP3135201.1"
                     /translation="MPTLRFPFHLANHNKDAAINILIIFISIGSIIFNVNYFHTTIVK
                     NGQIINQPTNAFQSDFSLAALWRNENHAGVKDANPVAVNQETPKLSIALNGIVLTSND
                     ETSFVLINEGSEQKRYSLNEALESAPGTFIRKINKTSVVFETHGHYEKVTLHPGLPDI
                     IKQPDSESQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQPGDIALRINNL
                     SLTHPDEVSQALSLLLTQQSAQFTIRRNGVPRLINVSVGELTGMNGLRHERTQ"
     gene            27382..29334
                     /gene="gspD"
                     /locus_tag="IT892_001979"
     CDS             27382..29334
                     /gene="gspD"
                     /locus_tag="IT892_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
                     /protein_id="HAP3135202.1"
                     /translation="MKGLNKITCCLLAALLMPCAGHAENEQYGANFNNADIRQFVEIV
                     GQHLGKTILIDPSVQGTISVRSNDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVR
                     SANVKTSPGMIADSSRPGVGDELVTRIVPLENVPARDLAPLLRQMMDAGSVGNVVHYE
                     PSNVLILTGRASTINKLIEVIKRVDVIGTEKQQIIHLEYASAEDLAEILNQLISESHG
                     KSQMPALLSAKIVADKRTNSLIISGPEKARQRITSLLKSLDVEESEEGNTRVYYLKYA
                     KATNLVEVLTGVSEKLKDEKGNARKPSSSGAMDNVAITADEQTNSLVITADQSVQEKL
                     ATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQFTNTGLPIFNAAQG
                     VADYKKNGGITSANPAWDMFSAYNGMAAGFFNGDWGVLLTALASNNKNDILATPSIVT
                     LDNKLASFNVGQDVPVLSGSQTTSGDNVFNTVERKTVGTKLKVTPQVNEGDAVLLEIE
                     QEVSSVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDI
                     PLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSLSKEKYTRYRQEQQQRIDGKSK
                     ALVGSEDLPVLDENTFNSHAPAPSSR"
     gene            29344..30825
                     /gene="gspE"
                     /locus_tag="IT892_001980"
     CDS             29344..30825
                     /gene="gspE"
                     /locus_tag="IT892_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HAP3135203.1"
                     /translation="MRIHSPYPASWALAQRIGYLYSEGEIIYLADTPFERLLDIQRQV
                     GQCQTMTSLSQADFEARLEAVFHQNTGESQQIAQDIDQSVDLLSLSEEMPANEDLLNE
                     DSAAPVIRLINAILSEAIKETASDIHIETYEKTMSIRFRIDGVLRTILQPNKKLAALL
                     ISRIKVMARLDIAEKRIPQDGRISLRIGRRNIDVRVSTLPSIYGERAVLRLLDKNSLQ
                     LSLNNLGMTAADKQDLENLIQLPHGIILVTGPTGSGKSTTLYAILSALNTPGRNILTV
                     EDPVEYELEGIGQTQVNTRVDMSFARGLRAILRQDPDVVMVGEIRDTETAQIAVQASL
                     TGHLVLSTLHTNSASGAVTRLRDMGVESFLLSSSLAGIIAQRLVRRLCPQCRQFTPVS
                     PQQAQMFKYHQLAVTTIGTPVGCPHCHQSGYQGRMAIHEMMVVTPELRAAIHENVDEQ
                     ALERLVRQQHKALIKNGLQKVISGDTSWDEVMRVASATLESEA"
     gene            30822..32018
                     /gene="gspF"
                     /locus_tag="IT892_001981"
     CDS             30822..32018
                     /gene="gspF"
                     /locus_tag="IT892_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HAP3135204.1"
                     /translation="MNYRYRAMTQDGQKLQGIIDANDERQARLRLREEGLFLLDIRPQ
                     KSSGVKTRRPRISHSELTLFTRQLATLSAAALPLEESLAVIGQQSSNKRLGDVLNQVR
                     SAILEGHPLSDALQHFPTLFDSLYRTLVKAGEKSGLLAPVLEKLADYNENRQKIRSKL
                     IQSLIYPCMLTTVAIGVVIILLTAVVPKITEQFVHMKQQLPLSTRILLGLSDTLQRIG
                     PTLLATVFIVAVGFWLWLKRGNNRHRFHAMLLRVALIGPLICAINSARYLRTLSILQS
                     SGVPLLDGMSLSTESLNNLEIRQRLANAAENVRQGNSIHLSLEQTAIFPPMMLYMVAS
                     GEKSGQLGTLMVRAADNQETLQQNRIALTLSIFEPALIITMALIVLFIVVSVLQPLLQ
                     LNSMIN"
     gene            32028..32465
                     /gene="gspG"
                     /locus_tag="IT892_001982"
     CDS             32028..32465
                     /gene="gspG"
                     /locus_tag="IT892_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HAP3135205.1"
                     /translation="MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQK
                     AVSDIVALENALDMYKLDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADP
                     WGNDYVLVNPGEHGAYDLLSAGPDGEMGTEDDITNWGLSKKKK"
     gene            32473..32982
                     /gene="gspH"
                     /locus_tag="IT892_001983"
     CDS             32473..32982
                     /gene="gspH"
                     /locus_tag="IT892_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspH"
                     /protein_id="HAP3135206.1"
                     /translation="MNQQRGFTLLEMMLVLALVAITASVVLFTYGREDVASTRARETA
                     ARFTAALELAIDRATLSGQPVGIHFSDSAWRIMVPGKTPSAWRWVPLQEDAADESQND
                     WDEELSIHLQPFKPDDSNQPQVVILADGQITPFSLLMANAGTGEPLLTLVCSGSWPLD
                     QTLARDTRP"
     gene            32979..33356
                     /gene="gspI"
                     /locus_tag="IT892_001984"
     CDS             32979..33356
                     /gene="gspI"
                     /locus_tag="IT892_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417789.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HAP3135207.1"
                     /translation="MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQRNAIERMRNET
                     LALWIADNQLQSQDSFGEENTSSSGKELINGEEWNWRSDIHSSKDGTLLERTITVTLP
                     SGQTTSLTRYQSIDNKSGQAQDD"
     gene            33349..33936
                     /gene="gspJ"
                     /locus_tag="IT892_001985"
     CDS             33349..33936
                     /gene="gspJ"
                     /locus_tag="IT892_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspJ"
                     /protein_id="HAP3135208.1"
                     /translation="MINRQQGFTLLEVMAALAIFSMLSVLAFMIFSQASELHQRSQKE
                     IQQFNQLQRTITILDNDLLQLVARRNRSTDKIMVLGEEAIFTTQSRDPLAPLSEAQTL
                     LTVHWYLRNHTLYRAVRTSVDGRKDQPAQAMLEHVESFLLESNSGESQELPLSVTLHL
                     QTQQYGGLQRRFALPEQLAREESPAQTQAGNNNHE"
     gene            33929..34912
                     /gene="gspK"
                     /locus_tag="IT892_001986"
     CDS             33929..34912
                     /gene="gspK"
                     /locus_tag="IT892_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HAP3135209.1"
                     /translation="MNNEQRGVALLIVLMLLALMAALAADMTLSFHSQLQRTRQVNHH
                     LQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQH
                     CFNLNALAKISDDPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDVDDSPRF
                     HGAEDSFYQSQTPPRHSANQMLFLTGELRQIKGITENIYQRLIPYVCVLPTTELSINL
                     NMLTENDIPLFRALFLNNITDADARVLLQKRPREGWLTTDAFLYWAQQDFSGVKPLVA
                     QVKRHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQQSAQIYRRTLQLY"
     gene            34927..36090
                     /gene="gspL"
                     /locus_tag="IT892_001987"
     CDS             34927..36090
                     /gene="gspL"
                     /locus_tag="IT892_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HAP3135210.1"
                     /translation="MPESLMVIRSSSTLRKHWEWMTFSADSVSSVHTLTDDLPLESLA
                     DQPGAGNVHLLIPPEGLLYRSLTLPNAKYKLTAQTLQWLAEETLPDNTQDWHWTVVDK
                     QNESVEVIGIQSEKLSRYLERLHTAGLNVTRVLPDGCYLPWEVDSWTLVNQQTSWLIR
                     SAAHAFNELDEHWLQHLAAQFPPENMLCYGVVPHGVAAANPLIQHPEIPSLSLYSADI
                     AFQRYDMLHGIFRKQKTVSKSGKWLARLAVSCLVLAILSFVGSRSIALWHTLKIEDQL
                     QQQQQETWQRYFPQIKRTHNFRFYFKQQLAQQYPEAVPLLYHLQTLLLEHPELQLMEA
                     NYSQKQKSLTLKMSAKSEANIDRFCELTQSWLPMEKTEKDPVSGVWTVRNSGK"
     gene            36087..36548
                     /locus_tag="IT892_001988"
     CDS             36087..36548
                     /locus_tag="IT892_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein M"
                     /protein_id="HAP3135211.1"
                     /translation="MIKSWWAEKSTSEKQIVAALAVLSLGVFCWLGVIKPIDTYIAEH
                     QSHAQKIKKDIKWMQDQASTHGLLGHPALTQPIKNILLEEAKRENLAITLENGPDNTL
                     TIHPVTAPLENVSRWLTTAQVTYGIVIEDLQFTLAGNEEITLRHLSFREQQ"
     gene            36548..37225
                     /locus_tag="IT892_001989"
     CDS             36548..37225
                     /locus_tag="IT892_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAP3135212.1"
                     /translation="MTMLLPLFILVGFIAGYFVNAIAYHLSPLEDKTALTFRQVLVHF
                     RQKKYAWHDTVPLILCVAAAIACALAPFTPIVTGALFLYFCFVLTLSVIDFRTQLLPD
                     KLTLPLLWLGLVFNAQYGLIDLHDAVYGAVAGYGVLWCVYWGVWLVCHKEGLGYGDFK
                     LLAAAGAWCGWQTLPMILLIASLGGIGYAIVSQLLQRRTITTIAFGPWLALGSMINLG
                     YLAWISY"
     gene            complement(37254..37730)
                     /gene="bfr"
                     /locus_tag="IT892_001990"
     CDS             complement(37254..37730)
                     /gene="bfr"
                     /locus_tag="IT892_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HAP3135213.1"
                     /translation="MKGDTKVINYLNKLLGNELVAINQYFLHARMFKNWGLKRLNDVE
                     YHESIDEMKHADRYIERILFLEGLPNLQDLGKLNIGEDVEEMLRSDLALELDGAKNLR
                     EAIGYADSVHDYVSRDMMIEILRDEEGHIDWLETELDLIQKMGLQNYLQAQIREEG"
     gene            complement(37802..37996)
                     /gene="bfd"
                     /locus_tag="IT892_001991"
     CDS             complement(37802..37996)
                     /gene="bfd"
                     /locus_tag="IT892_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HAP3135214.1"
                     /translation="MYVCLCNGISDKKIRQAVRQFSPHSFQQLKKFIPVGNQCGKCVR
                     AAREVMEDELMQLPEFKESA"
     gene            complement(38165..40858)
                     /gene="chiA"
                     /locus_tag="IT892_001992"
     CDS             complement(38165..40858)
                     /gene="chiA"
                     /locus_tag="IT892_001992"
                     /EC_number="3.2.1.14"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chitinase/lysozyme"
                     /protein_id="HAP3135215.1"
                     /translation="MKLNIFTKSMIGMGLVCSALPALAMEAWNNQQGGNKYQVIFDGK
                     IYENAWWVSSTNCPGKAKANDATNPWRLKRTATAAEISQFGNTLSCEKSGSSSSSNSN
                     TPASNTPANGGSATPAQGTVPSNSSVVAWNKQQGGQTWYVVFNGAVYKNAWWVASSNC
                     PGDAKSNDASNPWRYVRAATATEISETSNPQSCTSAPQPSPDVKPAPDVKPAPDVQPA
                     PADKSNDNYAVVAWKGQEGSSTWYVIYNGGIYKNAWWVGAANCPGDAKENDASNPWRY
                     VRAATATEISQYGNPGSCSVKPDNNGGAVTPVDPTPETPVTPTPDNSEPSTPADSVND
                     YSLQAWSGQEGSEIYHVIFNGNVYKNAWWVGSKDCPRGTSAENSNNPWRLERTATAAE
                     LSQYGNPTTCEIDNGGVIVADGFQASKAYSADSIVDYNDAHYKTSVDQDAWGFVPGGD
                     NPWKKYEPAKAWSASTVYVKGDRVVVDGQAYEALFWTQSDNPALVANQNATGSNSRPW
                     KPLGKAQSYSNEELNNAPQFNPETLYASDTLIRFNGVNYISQSKVQKVSPSDSNPWRV
                     FVDWTGTKERVGTPKKAWPKHVYAPYVDFTLNTIPDLAALAKNHNVNHFTLAFVVSKD
                     ANTCLPTWGTAYGMQNYAQYSKIKALREAGGDVMLSIGGANNAPLAASCKNVDDLMQH
                     YYDIVDNLNLKVLDFDIEGTWVADQASIERRNLAVKKVQDKWKSEGKDIAIWYTLPIL
                     PTDLTPEGMNVLSDAKAKGVELAGVNVMTMDYGNAICQSANTEGQNIHGKCATSAIAN
                     LHSQLKGLHPNKSDAEIDAMMGTTPMVGVNDVQGEVFYLSDARLVMQDAQKRNLGMVG
                     IWSIARDLPGGTNLSPEFHGLTKEQAPKYAFSEIFAPFTKQ"
BASE COUNT        10314 a        10637 c         9677 g        10364 t
ORIGIN      
        1 tctcttcgtt gttccgacca tcctgtgaag tgtttcacgt tgtcgtctca acggaggcgc
       61 attataggga tcccaatttt ttgcacaagt atttttttga tctttttttc tgtttgttgt
      121 tttttcaccc tttttgctgc aatcgcacac aaaacggtgc ttttttgcat actaaaagac
      181 ttgcacaagg ccaataatgc ccccaaagtc attagtaaat catttattgc tgaggtaagt
      241 atgtctgatg ttttacgccc ataccgcgat ctttttccac aaatcggtca gcgcgtaatg
      301 atcgacgata gcagtgtcgt gattggtgac gttcgtctgg ctgatgatgt ggggatctgg
      361 ccgctcgttg tgattcgtgg agatgtacat tatgtacaga tcggagcacg caccaatatc
      421 caggatggca gtatgttgca tgtcactcat aaatcctcgt acaacccaga tggcaaccca
      481 ttaaccattg gcgaagatgt cactgttggt cacaaggtga tgctccacgg ctgcaccatt
      541 ggcaatcgag ttttggttgg gatgggctca attttacttg atggcgcaat agtagaagat
      601 gatgtgatga ttggtgcggg tagtctggtc ccacaaaata aacggctgga gagcggatat
      661 ctgtatctcg gtagccccgt caaacagatc cgcccgttaa gtgatgaaga gaaggctggg
      721 ttacgctatt ccgcgaataa ttacgtgaaa tggaaggacg aatatctgga tcagggtaac
      781 cagacccagc cttgatcatc ttcactttgt tcctgaatta agttttccgc ttcttcttcc
      841 aggtcccagc gatgctgacg aaaactcgct aaccactgtt ctggcgtatc tccagtaaag
      901 cgatacgcca gactctcgcc agagatcgcg catgtcagtt gcataccatt cacgagagcg
      961 ggaaaacata cacatttttt attctcgtcc cactcttccc tgtccggaaa ctggatggcc
     1021 tgattcacgc ggacaattcc tcctgcaatt gctttataac tggttctacg tcaggcagaa
     1081 caccgtgcca gagaagaaag gcatgagccg cctgtgccac cagcattcct aaaccatcag
     1141 cattacgctt tgagcctcgc tgctcacacc atgccagaaa aggagttttt cctttctgat
     1201 agaacatgtc atagcaataa atgcctggat gaatgagcga tgacgggatc gccggaatat
     1261 caccactgat gccactggat gttgcattaa taatgagatc aaactcatga ccttccagtt
     1321 cgtccatact caacgcctga atactgccag tgtgcgcaaa caatttagcc aactcttccg
     1381 cgcgggatac cgtccgatta gttattgtca ccgcacagtc cagggaaagg agtggcagta
     1441 gtacgccgcg agatgctcca ccagcgccga taagcagaat acgtaaacca gggcggataa
     1501 aagacagacg ttccagatcg cttaacaagc ctacaccatc ggtattgtca cccagcaggc
     1561 gtccatcttc taaccgcatg agggtattaa cagcaccagc caacgctgcc cgttcagtaa
     1621 gctcatccgc tctggcaaaa gcctcttctt taaaaggcac cgtcacattc gcacctttac
     1681 caccagcact aaagaaagcg ttcagtgtgt tgatgaaatc attgatgggt gccaacacgc
     1741 gcccataggg atgttcaata ttcagttgct gagcaaattg ctgatgaatg aatggcgatt
     1801 tgctgtgggc tatcggatta ccaaaaacag cataggtttc cattatgtta cccctgtcga
     1861 aacagttcac ccgtcagggc atcgcggatt tctgaaggat ttaaacgccc ccccgtttca
     1921 ccaggcacaa ccgggaacgc cgcgccaaat tgtgcgcgaa cttcgtctac tgttcgacaa
     1981 ggtggcaatc cactcaagtt ggcactggta gaaaccagcg gtttaccata agcctggcac
     2041 aaagcaacca ccaacggatg gtcggtgact cgtacagcaa gcgaatcaaa gcggcccgtc
     2101 aaccagcgcg gtgttgtcgc aggcgcggga aagacaaagg tgacaggacc tggccagcgg
     2161 gaaaaaatgg tttcacgctg cacgtcagtc aacatggtgt catcaatata gggtttaagc
     2221 tgctcgtaat ttgctgcgat taaaatcagc cccttatcaa ccggacgctg ttttaactcc
     2281 aacagtcgca tcactgctgt ttcgctatca ggatcgcacc caacaccgaa aacggcttcc
     2341 gttggatagg cgatgacacg ttcttcattg agaacatcta tcgcagctgc gatagcgtct
     2401 ctttgcaggt tattattcac gttattattc cgccgaaacc ggctttccac attgtttact
     2461 ggcacaaaag tgttttacac cctgcgcggt tttcttttcg atgagtagcg gataatgaca
     2521 ctcagggcat tctccagcta tgggtttgaa gttaatggca aattgacact ccgggtagcg
     2581 atcacaagag tgaaatgttt tgccataacg ggagcggcgc tggaccagat ggcccgtccg
     2641 acattggggg catgtaattg ctgtttcgtc cggtttatcg ataagttcgg tatgttcgca
     2701 ttcagggtag ttaatgcaac caataaacat accaaagcgt ccctggcgta ataccagatt
     2761 tgcgccacat gcagggcaaa cctgcccctc cagaactttg acgatatgtc catccgctga
     2821 agatttcaga ggacggacgt agtcacacgc cggatactgt gagcatccaa gaaacggacc
     2881 gtgtttcccg gatcgaataa ccagttcagc cccgcacttt gggcaggact cattattacg
     2941 caccgtgaac agtgctgatt tcgccataac aacttatgct gaattaaaga aatgattaat
     3001 gcagcatacc ttcattcact tcaaagagta attcttccat ttgctggtac gcattttcgc
     3061 agcccggaat attgaacaac accatcagga tcacccattt cagatcatcc agttcgaact
     3121 ctgcgttatc cagcgcgagc actcgctcta tcaccatttc acgagtttca aggttgagca
     3181 cctgaatctg ctcaaggaaa agcagaaacc cacggcagct ggcatccagt cgttcacact
     3241 cttccggtgt ataaatacgc atggagagag gatccgaggc cagttgcatc ggttctgcca
     3301 acccttcctg ataatcagca agtttttcca gccatagcag ggcattgtag atatcttctc
     3361 gctcaaaacc tgcgtcggta agatcctgtt caagtttgtc ttgatccaca cgcaactcag
     3421 cttctgtgtg aatataggtt tcaaacaaat acattagtac gtcgaacatg gcatgccctc
     3481 ctcaatcgga catagccgcc gggtacagct gcgatccatc ctgctaactc cagttcgagt
     3541 agttgagtaa ctacctctgg cacaggttgg ccggcacgtt cagcgacgac gtcaacaggt
     3601 gttacctcat ctcctacgtt agccaggagc tcaggaaatg gcaatgccac gtcttgctga
     3661 tctggtgaat aaaatgaatt ttcaggggcg tctggcaacc agtgcaatcc aaattgcaag
     3721 ttttccagaa tttcttccgg ttccgtcaca agaatcgcac cttgttttat taaccagtga
     3781 ggcccttcgc ttcccggatt ccctattgga cctggcaagg caaaaacttc tcgcccctgc
     3841 tcaagcgcac aacgtgctgt caccagcgaa ccactacgca aagccgcttc caccaccagt
     3901 acacctttac ttagaccact gataatgcga tttcttcgtg ggaaattgta agcaaggggt
     3961 ggaacatcga ggggaaattc cgagacgaga gcgcccccct gttcaagcag actggcagcc
     4021 agtcgggcat gacggcgggg atgaatggta ttaagtccat tccccaatac agcaatgctg
     4081 acgccattta cctgtaaggc tgctttatgc gctacaccat cgattccacg cgccagtcca
     4141 ctcgtaattg tcactccacg cgtcgccaga gtttcgcaaa ataatcgtcc ccatcgctcg
     4201 ccataccatg aatgcgcccg actccccact acggcaagct gaaatgaatg cagcgcgtgc
     4261 agttctcctt caacaaacag tgcgccgggg taatctgtcg tcgccagaag ttgaggagga
     4321 taaaattcgc tgtccgcagg aattaaatga tggttgggtt gctccaacca acaaagtgag
     4381 ctttcgatac tctttcgtgg aaatgaaaga aagcgttgtg cctgccgcaa tgtaagccct
     4441 gtttgctgca atacaaccgc atcaatatgc gactgttttg ccacccagtg agcgatacgg
     4501 accatatcat cgccgtacaa gctgctgata ctcattaaac gcagccaaat ttctgtatcg
     4561 accatcctta tctccctgcc ataagcagcc ttagcaatct ttgcgattgg tcagtgatgc
     4621 tgtcaatcag agggggattt gtctagaata gaagaaataa tctttctaac tcctgaacac
     4681 atctctggag atttatgtca gttttgcaag tgttacatat tccggacgag cggcttcgca
     4741 aagttgctaa accggtagaa gaagtgaatg cagaaattca gcgtatcgtc gatgatatgt
     4801 tcgagacgat gtacgcagaa gaaggtattg gcctggcggc aacccaggtt gatatccatc
     4861 aacgtatcat tgttattgat gtttcggaaa accgtgacga acggctagtg ttaatcaatc
     4921 cagagctttt agaaaaaagc ggcgaaacag gcattgaaga aggttgcctg tcgatccctg
     4981 aacaacgtgc tttagtgccg cgcgcagaga aagttaaaat ttgcgccctt gaccgcgacg
     5041 gtaaaccatt tgaactggaa gcagacggtc tgttagccat ctgtattcag catgagatgg
     5101 atcacctggt cggcaaactg tttatggatt atctgtcacc gctgaaacaa caacgtattc
     5161 gtcagaaagt tgaaaaactg gatcgtctga aagcccgggc ttaaggataa gaactaacgt
     5221 gtcagaatca ctacgtatta tttttgcggg tacacctgac tttgcagcgc gtcatctcga
     5281 cgcgctgttg tcttctggtc ataacgtcgt tggcgtgttc acccagccag accgaccggc
     5341 aggacgcggt aaaaaactga tgcccagccc ggttaaagtt ctggctgagg aaaaaggtct
     5401 gcccgttttt caacctgttt ccctgcgtcc acaagaaaac cagcaactgg tcgccgaact
     5461 gcaggctgat gttatggtcg tcgtcgccta tggtttaatt ctgccgaaag cagtgctgga
     5521 gatgccgcgt cttggctgta tcaacgttca tggttcactg ctgccacgct ggcgcggtgc
     5581 tgcaccaatc caacgctcac tatgggcggg tgatgcagaa actggtgtga ccattatgca
     5641 aatggatgtc ggtttagaca ccggtgatat gctctataag ctctcctgcc cgattactgc
     5701 agaagatacc agtggtacgc tgtacgacaa gctggcagag cttggcccac aagggcttat
     5761 caccacgttg aaacaactgg cagacggcac ggcgaaacca gaagttcagg acgaaactct
     5821 tgtcacttac gccgagaagt tgagtaaaga agaagcgcgt attgactggt cactttcggc
     5881 agcacagctt gaacgctgca ttcgcgcttt caatccatgg ccaatgagct ggctggaaat
     5941 tgaaggacag ccggttaaag tctggaaagc atcggtcatt gatacggcaa ccaacgctgc
     6001 accaggaacg atccttgaag ccaacaaaca aggcattcag gttgcgactg gtgatggcat
     6061 cctgaacctg ctctcgttac aacctgcggg taagaaagcg atgagcgcgc aagacctcct
     6121 gaactctcgt cgggaatggt ttgttccggg caaccgtctg gtctgatagt ccactcttct
     6181 aagcccggtc ttgccgggcg tttttatact tatgaaaaaa caacgtaatt tacgtagcat
     6241 ggcggcccag gccgttgaac aagtcgtcga gcaagggcaa tcattaagca acattctgcc
     6301 accgctccag caaaaagttt ccgataaaga caaagcactt cttcaagagt tgtgctttgg
     6361 cgtactgcgt acgctttcgc agttagactg gctgattaat aagttaatgg cccgtccgat
     6421 gaccggcaaa cagcggaccg tgcattacct gattatggtt ggtttgtatc aactgcttta
     6481 tacccgcatt ccacctcatg ctgcgctggc tgaaacggtt gaaggcgcta tcgcaattaa
     6541 gcgtccgcaa cttaaagggt tgataaacgg tgtattacgc cagttccagc gtcagcaaga
     6601 agagttatta gccgagttta atgccagtga tgcacgttat ctgcatcctt cctggttgct
     6661 gaagcgtctg caaaaagcgt atccagagca gtggcaatcc atcgtcgaag ccaataacca
     6721 gcgtccgcca atgtggctgc gtattaatcg tacgcatcat tcccgcgaca gctggcttgc
     6781 attgctggat gaagcaggaa tgaaaggttt cccgcatgcg gattaccctg atgctgtacg
     6841 tctggaaaca cctgcacctg ttcatgcgct acctggtttt gaagacggat gggttaccgt
     6901 tcaggatgca tcagcacaag gttgcatgac ctggcttgcg ccacaaaacg gtgaacacat
     6961 tttggatctt tgtgccgccc ccggcggtaa aacaacgcat atccttgagg tggcaccaga
     7021 agcgcaggtt gttgcggttg atatcgacga acagcgcctc tctcgggttt acgacaattt
     7081 aaaacgcctt ggtatgaagg cgaccgtgaa acaaggtgat ggccgttacc cttctcaatg
     7141 gtgtggcgag caacagtttg atcgcatttt attagatgcg ccttgttcag caaccggtgt
     7201 gattcgtcgc catccagata ttaaatggtt acgtcgcgat cgcgatatcc cggaactcgc
     7261 gcaattgcag tctgaaattc tcgacgccat ttggccgcat ttaaaaaccg gtggaactct
     7321 ggtctatgcc acctgttcgg tgttaccgga agagaatagc ctgcagatta aagccttttt
     7381 gcaacgtacc gctgatgccg aactttgcga aacaggaaca ccagagcaac cgggtaaaca
     7441 aaatctacct ggtgccgaag agggcgacgg cttcttttac gctaagctaa tcaaaaagtg
     7501 atgagataac gggtcgcgac tgatgaaaat tatcattctg ggtgccggcc aggttggcgg
     7561 cacactggcg gaaaacctgg ttggcgagaa caacgatatt actgttgtcg ataccaacgg
     7621 tgagcgtctg cggaccttac aggataaatt tgacctgcgg gtcgtgcagg ggcatggctc
     7681 tcatccacgc gtattgcggg aggcaggtgc cgacgacgcc gatatgctgg ttgctgtaac
     7741 cagttcagat gaaaccaata tggttgcctg ccaggtagcc tactcacttt tcaacacccc
     7801 taatcgcatc gctcgtatcc gctcaccaga ctacgtgcgc gatgccgata agctatttca
     7861 ttcagatgct gtgccgattg atcatctgat cgcaccagag cagttggtta tcgataatat
     7921 ttaccgactg attgagtatc ccggcgcatt gcaggtggtg aacttcgctg agggtaaagt
     7981 cagcctggct gtggttaaag cctattatgg cggcccgctg attggtaatg cactttcgac
     8041 catgcgcgaa catatgccac atatcgatac tcgtgtggca gcaattttcc gccacgatcg
     8101 ccccattcgt ccgcaaggtt cgaccattgt tgaagctggt gatgaagtgt tctttattgc
     8161 cgcttcacag catatccgcg cggtgatgag tgaattacag cgactggaaa aaccgtataa
     8221 gcggatcatg ctggttggtg gcggtaatat cggtgcaggg ctggcgcgtc gtctggaaaa
     8281 agattacagc gttaaactca tcgaacgtaa tcagcagcgc gctgccgaac tggcggaaaa
     8341 gttacagaat acgatcgtct tttttggtga tgcgtcggat caagaactac tggccgaaga
     8401 acatatcgat caagttgatc tgtttattgc cgtcaccaac gatgacgagg ccaatatcat
     8461 gtccgccatg cttgccaaac gtatgggtgc gaaaaaggtg atggtattga tccagcgtcg
     8521 cgcttatgtg gatctggttc aggggagcgt tatcgatatt gcgatttcac cacaacaagc
     8581 aactatttct gcgttgctta gccatgtgcg aaaagcagat attgttggtg tttcctcatt
     8641 gcgccgcggc gtagcagaag ctattgaagc cgttgctcac ggtgatgaaa gcacctcacg
     8701 cgttgtcggc agagtcattg acgaaatcaa gctaccgcca ggaacgatta ttggagcggt
     8761 ggtacgtgga aacgacgtga tgattgccaa tgacaatttg cgcattgagc aaggcgatca
     8821 cgtaattatg ttcctcacag ataaaaagtt tattaccgac gtcgaaagac tcttccagcc
     8881 aagccctttc ttcttgtaat taataaggcg tctaatgacg ccttattatt tccctttgat
     8941 tatcaaggat taattaaatt cattcctggc aggaaaatgg cttaacattt gttagactta
     9001 tggttgtcgg cttcataggg agaataacat gagcattatt aaagaatttc gcgaatttgc
     9061 gatgcgcggg aacgtggtgg atttggcggt gggtgtcatt atcggtgcgg cattcgggaa
     9121 gattgtctct tcactggttg ccgatatcat catgcctcct ctgggcttat taattggcgg
     9181 gatcgatttt aaacagtttg ctgtcacgct acgcgatgcg cagggggata tccctgctgt
     9241 tgtgatgcat tacggtgtct tcattcaaaa cgtctttgat tttctgattg tggcctttgc
     9301 catctttatg gcgattaagc taatcaacaa actgaatcgg aaaaaagaag aaccagcagc
     9361 cgcacctgca ccaactaaag aagaagtatt actgacagaa attcgtgatt tgctgaaaga
     9421 gcagaataac cgctcttaac aagcgcctga aagcagaaga ccagtggtaa aaaagtgatt
     9481 tactttcttg ccactggcct cccagttccc ccgattgcca tgttttcctt ttcgcatgta
     9541 actgcctttc cccttcttat ttttctctac gcgctgtcgg aataagggat catgtagtaa
     9601 tgcttctatc gcattatcct ttatctgccc tttagtatgc tgatatcgac tcataaaaac
     9661 tccagttggt tatttaacgg cgcgagtgta atcctgccag tgcaaaaaat caacaaccac
     9721 tcttaacgcc actcgcccct tgttcaagag cttcaagaat cgaacaataa acactgctat
     9781 gagcagtccc acaacaggca tcgttaaggc gttgcaagga acgctgcata ctctgcaact
     9841 cggctatccg tgcttcgact tcctgcaatc tttcctgcac aatgcctttt gactcctgac
     9901 aggtatggtg ttcaggatcg atgcggatcg acagcaactc gcggatcgac tccagactga
     9961 aacctagttg tctggcatgg cggataaatt tcaatcgctg gagatcgctt tcggtatata
    10021 ggcgaaaccc accttcagta cgcacttcat gctccatcat ctgctgtttt tcgtaataac
    10081 gaatcgtgtc gggtgttact tccgccattt ttgccagctc accaatgcga tacatacata
    10141 ctccactagt tatcgttgat tttgtccaac aacttgtcag cataatcgcc gcgtaaaaaa
    10201 tcggtactca atccagcttg tcgcagcttc aattccagta atgacaatcg acggctaacc
    10261 tcttgatatt gcggatcatc gtgacggata cctttgagaa tatccagaag ctgaattgct
    10321 tctctccgtt gctcaagttc tggcggtaag caaccggcat tcttcagcaa gcgatacccc
    10381 gcacgtaatt ccggtggcac gtgagaatca tcatccagta tcaatggttc gccgctacct
    10441 gccaggttat caaactcacc tttcgcttgc gcttctgcta tatggcgctc tgcccactgg
    10501 tcaagtaacc acataaatac tccaggggat gaacaaaaag agtacagcta ttgtagataa
    10561 gtggggatac tacgggtata aaaaaacccg ccggggcggg tttttttacg ttgcttcaga
    10621 ttactctgca gcagcttctg ctttctctga acgatcaacc agctcgatgt aagccatcgg
    10681 cgcgttgtcg cctgcacgga agccacactt cagaatacga gtgtaaccac cggcacggct
    10741 cgcgaaacgc gggcccagtt cgttaaacag ttttgccacg atctcgttat cacgagtacg
    10801 ggcgaatgcc agacgacgat tagcaacgct atcagtcttg gcaagagtaa tcagcggctc
    10861 aactacgcgg cgcagctctt tcgctttagg cagagtcgtc ttgatgattt catgacgaac
    10921 cagtgaacct gccatattgc ggaacatagc ctggcgatgg ctgctgttgc ggttcagttg
    10981 acgaccactc ttacgatggc gcatgacctt atccttctca gtaaaacctt aacctgtgat
    11041 ccggttactc gtcagcgatg cttgccggtg gccagttttc caggcgcatg cccagagaca
    11101 gtccacggga agccagcacg tctttaatct cagtaagaga ttttttacca aggttaggcg
    11161 ttttaaggag ctcaacctcg gtacgctgta ccagatcacc gatatagtgg atagcttctg
    11221 ctttaaggca gttagcagag cggacagtca attccagatc gtcaacaggg cgcagcagga
    11281 tcggatcgaa ctctggtttc tcttctttca cttcaggctg acgtacatca cgtaagtcaa
    11341 cgaaagcttc cagttgttca gccagaatgg ttgccgcacg acgaatcgcc tcttcaggat
    11401 cgattgtgcc gttggtttcc atttcgatga ccagcttgtc caggtcggta cgctgttcta
    11461 cacgcgctgc ttcaacattg taggcaatac gctccacagg gctgtagcat gcgtcgacca
    11521 gcagacggcc gattgggcgc tcatcttctt ccgaatgaat tcgggtagaa gccggcacat
    11581 aaccacgacc gcgctgaact ttgatacgca tgctaataga cgcgttctca tcggtcaggt
    11641 ggcagatcac gtgctgcggc ttgacgattt cgacatcacc gtcgtgggtg atatcggctg
    11701 cagtcacagg gccaatgcca gatttattca aggtaagaat aacttcatct ttgccctgaa
    11761 ctctcaccgc cagccctttc aggttgagca ggatttccag gatatcttcc tgaacgcctt
    11821 ctttggtgct gtactcatgt agtacaccat caatctcaac ctcggtcacc gcgcaacccg
    11881 gcatcgatga gagcagaata cggcgcagtg cgttacccag agtatggcca aagccacgct
    11941 ctaaaggctc aagggtcacc ttggcgtgcg tcgaactcac ttgctcgata tcaaccaggc
    12001 gcggttttag aaactctgtc acagaaccct gcattgtgtc ctctctttgg tactaagctt
    12061 tacttggagt aaagctcgac gatcaggtgt tcgttaatgt ccgcagacag atcagaacgc
    12121 tccggcttac gcttaaacgt accttccatc ttgccagcat caacttccag ccaggttggc
    12181 ttttcacgct gctcagccag ctccagagcg gctttcacgc gagactgctt cttcgctttc
    12241 tcacgaatgc ttacaacgtc attcggacta acctgataag aagcgatgtt aacaacacga
    12301 ccgtttacca taattgcttt atggctaacc agctgacgtg cttctgcacg agtggcaccg
    12361 aagcccatac ggtatacaac gttgtccaga cgaccttcca gcagagccaa caggttttca
    12421 ccggtgttgc ctttcagacg tgctgcttct ttgtagtagt tacggaactg acgctccagc
    12481 acaccataga tacggcgaac tttttgcttt tcacgcaact gcacaccata gtcagacaga
    12541 cgcggtttac gcgcaccgtg ctggccagga gcttgttcaa ttttacactt ggtatcgatc
    12601 gcgcgaacgc cagacttaag gaataagtcg gtgccctcac gacggctcag cttgagctta
    12661 ggacccaaat atcttgccat tttctttctc caacaaacct ggaaaacgag gcgttatacg
    12721 cgacgttttt tcggcggacg acaaccgtta tgagggatcg gagtcacatc agtaatgtta
    12781 gtgatgcgga aacctgcggc gttcagagca cgaatagtag attcgcggcc tggacccgga
    12841 cctttaacca taacttccag attcttgatg ccgtattctt tcacggcgtc agcgcaacgc
    12901 tctgctgcaa cctgagctgc aaacggagtg gatttgcgag aaccacggaa accggaacca
    12961 ccggctgttg cccaacccaa cgcgttaccc tgacgatcag tgatagtcac gatggtgttg
    13021 ttgaaagaag catggatatg agccacgccg tcagagactt gttttcttac acgtttacgt
    13081 gcacgaattg gtgcctttgc cattattcaa tcaccccgat tatttcttga tcggtttgcg
    13141 cggaccctta cgggtacgtg cgttggtctt ggtacgctga ccgcgaaccg ggagaccacg
    13201 acgatgacgc aaaccgcgat agcaaccaag atccatcagg cgcttgatgc tcatgctgat
    13261 ttcacggcgc agatcacctt caacgacaaa tttggcaact tcgtcacgca gcgtgtcgat
    13321 ttgtccttca gacagctcac tgatcttaac atcttcagcg atacccgctg cagccaggat
    13381 ggctttagaa cgggtcttgc cgacgccata aatcgaagtt aatgcgatta cggcatgctt
    13441 atgatcagga atgttaatgc ctgctatacg ggccactatg cactcctact atttaatatg
    13501 tacgttccat gctgaaaagc ccgttttcag gatactcaaa tggaaacgca cagacataca
    13561 aaagattggc tggctaatct agccagctca acccaacttt gcaagaaaaa tatgcgaaaa
    13621 aatcagcctt ggcgctgttt atgcttcggc tcggcactgc aaatcacacg gatgacacca
    13681 tcacgcttaa cgattttgca gttacggcat aatttcttga cggaagcacg aactttcatt
    13741 tttactctcc gtaacttctc gggcgaccaa ttatcggccg tagcctttca ggttcgcctt
    13801 cttcaatgca gactcatact gactggacat catcagagtt tgcacttgag ccataaagtc
    13861 cataatcacg acaacaacga taagcagtga ggtcccaccg aagtagaacg gtactttcat
    13921 tgcatcacgc atgaactccg ggatcaggca gataaaggta atatacagcg caccaaccag
    13981 ggtcaggcgg gtcattactt tatcgatata cttcgccgtt tgctctcccg gacgaattcc
    14041 tggtacaaat gcaccggact tcttcaggtt atctgctgtt tcacgcgggt tgaaaaccaa
    14101 cgccgtgtag aagaaacaga agaagatgat tgcagacgca tagagtaaca cataaagcgg
    14161 ttgcccaggc tgcaaataca gcgaaattgt tgtcagccag ttccaaccag taccgccccc
    14221 gaaccatgac gcgatggtcg ccgggaacag aataatactg gaagcgaaga ttgccgggat
    14281 tacccccgcc atattcactt tcagcggtaa atgtgtgctc tgtgcagcat agacacgacg
    14341 accttgctga cgtttcgcgt agtttaccac aatgcggcgt tgaccacgct caacaaatac
    14401 aacaaagaac gtcactgcaa atactaatac tgcaaccaac agcaacacga ggaagtgcag
    14461 gtcgccttga cgcgcttgct cgatagtatg ggcaatggct ggcgggagtc ccgcgacaat
    14521 accggcgaag ataatgattg aaataccgtt gccgatacct cgttcagtaa tctgttcgcc
    14581 caaccacatc aggaacatgg ttcctgtgac cagacttaca acagcggtga agtagaatgc
    14641 aaagcccggg ttaatcacca ggccttgcat accaggcata ttcggcagac cggtagcaat
    14701 accgatcgac tggaatattg ccagcaccag agtaccgtag cgggtgtact ggctgatctt
    14761 acgacgacca gactcccctt ctttcttaat ttctgccaac gttgggtgaa ccaccgtcag
    14821 cagctggata atgatcgacg ccgaaatata cggcatgatc cccagagcaa agatagaagc
    14881 acggctgaga gcaccaccag agaacatgtt aaacatctca atgatggtgc ctcgctgttg
    14941 ctcaagcagt ttggcaagta cagcggcatc aataccaggg atcggaataa aagagccaat
    15001 acggaacaca atcagcgcac cgataacaaa cagcagtctg cgtttcagct cgcctaagcc
    15061 acctttggca ctttgaaaat ctaatcccgg ttgtttagcc atctgctact tattcctcga
    15121 ttttaccgcc agcagcttcg atagcagcac gagcgccttt agtaacacgc aggccacgaa
    15181 cagttaccgg agtcgttact tcgccagcca ggatcacttt cgcgaactcg atctggatac
    15241 cgataatgtt agccgctttc agcgtgttca ggtctactac accgccttct actttagcca
    15301 ggtcagacag acgaatttcg gctgtaatcg ctgctttacg agaagtgaag ccgaatttcg
    15361 gcagacgacg gtacagaggc atctgaccac cctcgaaacc gcgacgtacg ccaccgccag
    15421 aacgagactt ctgacctttg tgaccacgac caccggtttt accgaggcca gaaccgatac
    15481 cacgacccag gcgtttaccc gcctttttgg agccttcggc cggagacaga gtatttaaac
    15541 gcatctctta ctcctcaact ttaaccatga aggaaaccgc gttgatcata ccgcgaatag
    15601 caggagtatc ctcgcgctct acggtgtgac caatacgacg cagacccagg ccaagcagcg
    15661 ttgccttgtg tttcggcaga cgaccgattg cactgcgggt ttgagtaatt ttaatagtct
    15721 ttgccatggt ttatttcccc agaatttctt caacggattt accacgcttg gcagcgacca
    15781 tttctggaga attcatattt tccaggccat caatagttgc acgaaccacg ttgatcgggt
    15841 tggtggaacc ataggcttta gccagaacgt tatgaacccc agcgacttcc agaacggcgc
    15901 gcattgcacc accggcgatg ataccggtac cttcggaagc cggctgcatg aatacgcgag
    15961 aacccgtgtg aacaccttta acagggtgtt gcagagtgcc gttattcagc gcgacgttaa
    16021 tcatattgcg acgggctttt tccatcgctt tctggatcgc tgctggaact tcacgcgctt
    16081 taccgtaacc aaaaccaacg cgaccgttac catcgccaac tacagtcaga gctgtgaagg
    16141 agaaaatacg accaccttta acggttttag atacgcggtt taccgcgatc agcttttcct
    16201 gcagttcgcc agcttgtttt tcgatgtgag ccatcttaca cctctacctt agaactgaag
    16261 gccagcttca cgggcagcat ctgccagtgc ctggacacga ccatgatatt ggaacccgga
    16321 acggtcaaag gatacatctt tgatgccttt ttccagagcg cgttcagcga cagctttacc
    16381 cacagctgca gccgcgtctt tgttaccggt gtacttcagt tgttcagcga tagctttttc
    16441 tacagtagaa gcagctacca gaacttcaga accgttcggt gcaattacct gtgcgtaaat
    16501 gtgacgcggg gtacgatgta ccaccaggcg agttgcgccc agctcctgga gcttgcggcg
    16561 tgcgcgggtc gcacgacgga tacgagcaga tttcttatcc atagtgttac cttacttctt
    16621 cttagcctct ttggtacgca cgacttcgtc ggcgtaacga acacccttgc ctttataagg
    16681 ctcaggacga cggtaggcgc gcagatccgc tgcaacctgg ccgatcacct gcttatcagc
    16741 gcctttcagc acgatttcag tctgagtcgg acattcagca gtgatacccg caggcagctg
    16801 atggtcaaca ggatgagaga aacccagaga caggttaatc acattgcctt taaccgctgc
    16861 acggtaacct acaccaacca gctgcagctt cttagtgaag ccttcggtaa caccgataac
    16921 cattgagttc agcagggcac gcgcggtacc agcctgtgcc caaccgtctg cgtaaccatc
    16981 acgcggaccg aaggtcaggg tattatctgc atgtttaact tcaacagcat cgttgagagt
    17041 acgagtcagc tcgccgtttt tacctttgat cgtaataacc tgaccgttga tttttacgtc
    17101 aacgccggca ggaacaacga ccggtgcttt agcaacacga gacatttttt cctccgatta
    17161 ggctacgtag cagataattt cgccaccaag accagcctgg cgcgctgcac gatcagtcat
    17221 aacaccttta gaggtagaaa caactgcgat acccagaccc gccataactt tcggcagctc
    17281 atctttacgt ttatagatgc gcagacctgg gcggctgaca cgctgaatgc tttctacaac
    17341 agctttgccc tggaaatact tcagagtaag ttccagttca ggcttggtgt cgccttcaac
    17401 tttaaaatct tcaataaaac cttcttcctt cagcacgttg gcgattgcca ctttcagctt
    17461 ggaggaaggc atggtgaccg cagctttgtt cgcggcctga ccgttacgga tacgggtcag
    17521 catatccgcg atcggatctt gcatgctcat ctgtctttac tcccgtgatt caattggtga
    17581 caattaccag ctagcctttt tcagacccgg gatttcaccg cgcatagcgg cttcacggac
    17641 cttaatacgg ctcaacccga acttccgcag gaaaccatgc ggacgacctg tttgacggca
    17701 gcggttacgc tgacgagacg ggctggaatc acgcggcaga gtctgcagct tgagaacagc
    17761 gttccaacga tcttcgtcgg aagcgttcac atcagagatg atcgctttca gttcagcgcg
    17821 tttcgcgaag tatttatcag ctaaagctac gcgttttact tcgcgtgctt tcattgattg
    17881 cttagccatt tagtaaccct accttacttg cggaacggga agtcaaaggc agccagcaga
    17941 gcgcggcctt cttcgtcaga tttcgcagta gtggtaatgg taatatccaa accacgaacg
    18001 cggtcgactt tatcgtagtc gatttctggg aagatgatct gctcacggac acccatgctg
    18061 tagttaccac gaccgtcgaa agacttagcg gacaggccac ggaagtcacg gatacgaggt
    18121 acagcaatag tgatcaggcg ctcaaagaac tcccacatgc gttcgccacg cagagttact
    18181 ttacagccga tcggatagcc ctgacggatt ttgaagcctg caacagattt gcgtgctttg
    18241 gtgatcagcg gtttttgacc ggagattgct gccaggtctg ctgctgcgtt atccagcagt
    18301 tttttgtcag cgatcgcttc accaacaccc atgttcaggg tgatcttctc gacccgaggg
    18361 acttgcatga cagaattgta gttaaactca gtcatgagtt ttttaactac ttcgtctttg
    18421 tagtaatcat gcagtttcgc catcgtacta ctccaaatta cttgatagtt tcgctgttag
    18481 acttgaagaa acggactttt ttaccgtctt cgaatctaaa gcctacacgg tcagccttgc
    18541 cggttgccgc attgaagatt gctacgttgg aaacctgaat agcggcttct ttttcaacga
    18601 tgccacccgg ttggttcagg gccggaaccg gcttctgatg tttcttaacc aggttgatac
    18661 cttcaacaat gaccttgccg gaagacagga cattcttaac tttaccgcgt ttacctttat
    18721 ctttaccggt taacacgata acttcgtcat cacgacggat tttcgctgcc atgattcgct
    18781 ccttagagta cttctggtgc cagagagata attttcatga acttctcact acgaagctca
    18841 cgagttaccg gcccaaaaat acgcgtaccg ataggctgct cgctgttgtt gttcagaaga
    18901 acacaagcat taccatcgaa gcgaatgaca gaaccgtccg ggcgacgaac acccttcttg
    18961 gtgcgcacca ctaccgcctt cagcacatca ccttttttga ccttaccacg cggaattgct
    19021 tctttgatgg tgatcttgat gatgtcgcct acgcctgcgt agcgacggtg cgagccaccc
    19081 agaaccttga tacacattac gcgacgtgca ccggagttgt cggcgacgtt cagcatagtc
    19141 tgttcttgga tcattttagt gctccgctaa tgtcaactac tactgagacc cgaaaatcag
    19201 gtcgttaaaa atccccatat cgagggcgcg gcattataac accgcttcaa ggatatgggt
    19261 agaaaaaata aacggctcat ttctgagccg tttattcgta ttgagagagt gtactgtatt
    19321 acagaaccgc tttctctaca acgcgaacca gcgtccagga tttagtcttg gacagcggac
    19381 ggcattcgcg gatttcaacc acgtcaccga taccgcattc gttgttctcg tcatgtacgt
    19441 gcagtttggt cgtacgcttg atgaatttac cgtagatcgg gtgtttcaca aaacgttcga
    19501 tagcaacaac aatggatttc tccattttgt cgctaacaac gcgaccttgc agagtacgga
    19561 ttttatcggt cattacgcac ccgccttctc gttcagtaaa gtcttaacgc gtgcgacatc
    19621 gcgacgcact tgcttcaaca ggtgagactg ttgcagctgg ccacttgcag cctgcatacg
    19681 caggttgaac tgctcacgca gcaggttcag cagctcggtg ttcagctctt caacgctctt
    19741 ctcacgcagc tcttttgctt tcattacatc accgtcttag ttacaaaggt ggttttaatc
    19801 ggcagtttcg ctgctgccag cttgaatgct tcacgggcca gctcttccgg aacaccgtcc
    19861 atttcataca ggactttacc cggctgaatc aaggcaaccc aatactccac gttaccttta
    19921 cctttaccca tacgcactgc cagcggcttt tcagtgatcg gtttgtccgg gaacacacgg
    19981 atccagatct taccttgacg cttaactgca cgggtcatag cacgacgtgc tgcttcgatc
    20041 tgacgggcag tcagacgacc acggccaaca gctttcagac cgaagctgcc gaagctaaca
    20101 tccgtaccct gcgccagacc gcggttacgg cctttgtgca ttttacggaa ttttgtacgc
    20161 tttggttgta acatcagcga cgctccttat ttacggcctt tacgctgctg ctttttaggc
    20221 tgagcagccg gtttttccgg ttgttcaaca gcagccatac cacccaggat ctcgcctttg
    20281 aagatccaca ctttaacgcc gattacaccg taagtggtgt gcgcttcaga ggtgttgtag
    20341 tcgatgtcag cacgcagagt gtgcagcggt acgcgacctt cgcggtacca ttcggtacgt
    20401 gcgatttccg cgccgcccag acggccgcta acttcaactt taataccttt agcgcccaga
    20461 cgcattgcgt tctgtacagc acgcttcata gcacgacgga acataacgcg acgttccagc
    20521 tgagaagtga tgctgtcagc aaccagtttt gcgtccagtt caggcttacg aacttcggcg
    20581 atgttgatct gtgcaggaac gccagcgatg tccgctacga ccttacgcag tttttctacg
    20641 tcttcacctt ttttaccgat aacgataccc gggcgagcag tgtgaatggt tacacggatg
    20701 ctcttagccg gacgctcgat aacgatacga gatacggacg ctttagccag ttccttagtc
    20761 aggtactgac gtactttaaa atcgctgtcc aggttgtcag cgaattcttt ggtgttcgca
    20821 aaccaggtag agttccatgg ttttacaata cccaggcgaa taccattagg atgtactttc
    20881 tgacccattg ctagtctcca gagtctcagc gatcggacac aaccacagtg atgtggctgg
    20941 tgcgcttcag gatgcgatct gcacgacctt ttgcacgcgg cataatgcgc ttcatgctcg
    21001 ggccttcgtc tacgaaaatt ttcgtaactt tcagatcgtc aatgtcagcg ccatcgttgt
    21061 gttcagcgtt agcaatggca gattccagaa ctttcttgac cagtacagcc gctttcttgt
    21121 tggtgtaggt caaaatatcc agagcctgcg acactttctt accgcgaatc aggtcagcaa
    21181 caaggcgaac cttctgagca gaagaacgag catggcgatg tttagcgata gtttccatct
    21241 cttcctccta ccttatttct tcttcgcttt tttatcagca gcgtggccgc gataagtacg
    21301 agtcggtgcg aattcaccca gtttgtgacc aaccatttcg tcggttacaa ataccggaac
    21361 gtgctgacga ccattatgga cagcgatggt caaaccgatc atgttaggaa agatcgttga
    21421 acgacgggac caagtgcgca ggggcttctt gtctccgctt tccaccgctt tctctacctt
    21481 cttcagcaag tgcaggtcaa taaaaggacc tttcttgaga gaacgtggca tggcttatcc
    21541 tctaaaatta tttgctacgg cgacgtacga tgaatttatc agtacgcttg ttgctgcggg
    21601 tcttcttacc tttggtctga acgccccacg gagttaccgg gtgcttacca aagttacgac
    21661 cttcaccacc accatgtggg tggtctaccg ggttcatcgc ggtaccgcga acggtcggac
    21721 gaacaccacg ccagcgtgca gcacctgctt tacccagaac gcgcagcata tgctcagcat
    21781 tgccaacttc gcccagagtt gcacggcagt ctgcttctac tttacgcatt tcaccagaac
    21841 gcagacgcag ggtgacataa gcaccatcac gagcaacgat ctgaacgtaa gtaccagcgg
    21901 aacgtgccag ctgaccgcct ttacctggtt tcatttctac gttatgaaca gtagaaccaa
    21961 ccgggatgtt gcgcatcggc agggtgttac ctggtttgat tgcagcatca acgccagact
    22021 gaatctggtc gccagctttc aggcctttag gggccaggat gtaacggcgt tcaccgtctt
    22081 tgtacagaac cagcgcgatg ttcgcggaac ggttcggatc gtactcaaga cgttcaacaa
    22141 ctgccgggat accgtctttg ttgcgtttga agtcaacaat acggtaagcc tgcttgtggc
    22201 caccaccgat atgacgagtg gtgatacggc cattgttgtt acgaccaccg gatttgctgt
    22261 ttttttccag caacggagca aaaggtttgc ccttgtgcag ctcagggtta accactttaa
    22321 ctacgtggcg acgacccgga gatgtcggtt tacatttaac aactgccatt gtattactcc
    22381 tccgacttac tcagcgccgc caacgaagtc cagattctgg ccttctttca gggtgacgta
    22441 agcttttttc cagtcgctac gacgaccgat acgctgtccg tgacgtttaa ctttcccttt
    22501 aactaccagg gtgttaacga cttcgacttc gacttcaaac agtttctgca cagcagcttt
    22561 gatttctgct ttggtcgcgt ctttagcaac tttgagtacg atggtgttgg atttttccat
    22621 cgcagtagac gctttttcag aaacgtgcgg tgcacgcagc accttcagca gacgttcttc
    22681 acgaatcatg ccagcatctc ctcaacttgc ttaacagcat cagcagtcat tacgactttg
    22741 tcgaaggcga tcaggctaac cgggtcgata ccagttgcat cgcgtacgtc aaccttgtgc
    22801 aggttgcgcg cagccaggaa caggttttcg tccagctcac cggtgatgat cagcacatct
    22861 tccagagcca tgtctttcag tttctgtgcc agcagcttag ttttcggcgc ttctacagag
    22921 aacttctcga caacgatcag acgatcctga cgtaccagtt cggacaggat gcttttcagc
    22981 gcgccgcggt acatcttctt gttaactttt tgactgtggt cctgcggacg agcagcaaag
    23041 gtcacgccac cagaacgcca gatcgggctc ttgatagaac cagaacgcgc acggccggtg
    23101 cctttctggc gccacggttt tttaccggaa ccagttactt cagcacgagt cttctgagca
    23161 cgagtaccct gacgagcacc agctgcataa gcaacaacaa cctggtgaac cagcgcttcg
    23221 ttgaaatcac gaccgaaggt agtttcggaa acagtcagcg cgctctgcgc gtctttcaat
    23281 actaattcca ttgctatctc cttacgcctt cacagctggt ttaacgatca ggtcgctacc
    23341 ggttgcaccc gggacagcac ctttaaccag cagcaggttg cgctcagcgt caacgcgtac
    23401 tacgtcaagg ctctgaacgg ttacacgttc gttacccatc tgacctgcca ttttcttgcc
    23461 tttgaacact ttgcccggag tctggttctg accgatagaa cccggaacgc ggtgagacaa
    23521 ggagttaccg tgagtagcgt cctgggtacg gaagttccag cgcttaacgg tacctgcgaa
    23581 acctttacct ttagaggtgc cagttacgtc aactttttta acgtcagcaa acagttcaac
    23641 gctaatgctc tgacctacag tgaactcttc gccttcagcc aggcggaatt cccacagacc
    23701 acggccagct tctacgccag ctttagcgaa gtggccagct tcaggcttgg tcacacggtt
    23761 agctttttta gcaccggtgg tcacctgaat agcacggtag ccatcgttag ccaggtcttt
    23821 aacctgagta acgcggtttg cttcaacttc gattacggtt actgggatag aaacgccgtc
    23881 ttctgtgaag atacgggtca tacccacttt tttaccgact aaaccaatca ttgtttcaac
    23941 ctctcaatcg ctcaatgacc tgattaaccc aggctgatct gcacgtctac accggcagcc
    24001 agatccagac gcatcagagc atcaacggtt ttctcggttg gctcaacgat gtcaaccaga
    24061 cgcaagtgag tacggatttc gtactgatcg cgcgcgtctt tgttgacgtg cggggagatc
    24121 agaacagtga agcgctcttt gcgtgtcggc agcgggatcg gaccacggac ctgcgcacca
    24181 gtgcgcttgg cagtctcgac gatttccgcg gttgcttgat cgatcagacg atgatcaaac
    24241 gctttcaggc ggatacggat tctttggttc tgcatgagac cagagctcca attattttat
    24301 aaacgaaaat gattactcct cagacccatt acgattgatg ggagagtgta accgttctta
    24361 cgtagctccc cgattgggag cattgttagg tagccaaatt cggctaactg aggttcagat
    24421 tgaacctgct gtcaactacg acaagcccgc gcattataca tacttaacca ccgaacgcaa
    24481 gcgtattgct agtaaagtaa acagccttcg ggttatctct caagttcgtt cagtgcattt
    24541 ttgacacgct ctcttaaacc ggctttctct tcgctttctt ccacagtatt ttcttcgtct
    24601 tcagaagaag agggggcatt ctcaaccgcg acgcctgggt catcttcctc ctcgacggat
    24661 tcgacgacgg ggagtggctg ttttttgaag aaatagtgtt gtgttgattg tttaaaagcg
    24721 ggcgtttcag cctctacagt gacttcggct tttactatcc aaagcaccca tagctgcctg
    24781 gcatacccac caaccagcac cattcctgca aaccacaggc aaatcagtaa taaacaaatt
    24841 acatatatta tggtgctgtg tttttgtcgg gagaagatac cagggtgacc tgtttctttc
    24901 tgctcacgcg cggcgatata gaattcaaac atgtcatttc cccttcactg ttgtttccgg
    24961 ggaaatattt gcttcatccc gatataagta ggcactctcc cctgccacct gccagagatg
    25021 tactaacgtt gaaaagccaa caacaccgtc agttttcaag tggtggcttt tttgaaattg
    25081 ctttattttt tctaccaaca agggacgcca ctccgccgaa ggttctgtcg aaatatgcaa
    25141 tgcgcggttt aacatcgttt ccagccagag aatctcttcc tcgctgctat cacgcgtaat
    25201 ggtactctcc ccttccggcg acattttcca caacagaaga taatcacccg tccataccga
    25261 ctcaaaccat ttatgtgtca gcgtccacgt ttgctgacct acgaggacat caacgctagc
    25321 ctcaccgacg cgaacgacca caacaggcaa ttttttgtcc ccgactttaa gcgatgcgat
    25381 ccagggcaaa ttctgatcta ccaatgtttg taaagaagca ttcccacttt tacatgccag
    25441 ccccgctctt actgcctgat cgcaccaggc cgaatcagct gggacctcgt acccccatac
    25501 gccgtataac acgcttagcg cctcactatc gcgcatcacc acatgagcaa tatccttagt
    25561 catatcttgt ttaactactg gcgttacggg tatcagccac gcaggaacgg gtaacgtagc
    25621 tgtaaaagag gacagcagta gccaaccaca ggtaagagcg ataatggttc cactcatcac
    25681 cacggcaagc tgcattttcc gggggcggtt atcacccaat atgcggtaaa tcattcgcca
    25741 ttgttttgct gtgaaaacgc tggtctgctc ggcttgctgt aataagcgaa ttgtttcgcc
    25801 ggcaagcgcc agctttctgc gatcgccccg acataataaa gctatccgtt tcagaactct
    25861 ggcggttaaa aggagatcgg gttggtcaat attctgacct tcaaggatgc ttgccttaag
    25921 ttcgtgctcc gtcagacgtc ctatcgagac aagttcaatg ccctgttttt taaaatcacg
    25981 ttcgactttt cgatcgggtc tgccgatcag caaaaattga ccgtcaggaa taagagatat
    26041 tgcgcgttgg agatcatcaa gtatgcggcg gtgattcagg tgagcatttt caataataat
    26101 aagagggcag cgactatcag ttcgatgaag cgcatgcagt aattgccccg ccatctcatc
    26161 tcgcgtccag gcgctgtcac ggcagccctg ttcagccgcg ttatcgtcgg taacgatcca
    26221 tgcggcctta ccttgccagg aaacaacgag gcttaaagta atcacacggc gatgtttatc
    26281 tttttgcagt tgctgcgcca gccaggtttt tccacttcca gcctcaccca acaaatagca
    26341 tagacgccag gtttgacgtt tctcacacaa ccaggaaaga ataacttctc ttctcgtaga
    26401 catagaactt cctgttttaa ttattgatta tccttaatca taaaaataat gtatgtattt
    26461 attaattaaa tacatattac taatataaat aaattttgct tgattcatgc aagcggcatt
    26521 aatactattt atactaacgt caatatacaa cccacccaat ctattttatt agaacataca
    26581 tcgtgcccac actacgtttc cccttccatc tggcgaatca taataaagat gctgccatca
    26641 atatattgat tatatttata agcatagggt cgattatttt taatgtgaat tatttccata
    26701 caactatagt taaaaatgga cagatcatta atcaaccaac aaacgcattt cagtctgatt
    26761 tcagccttgc cgctttatgg cgtaacgaaa atcatgctgg ggtaaaagat gcaaatcccg
    26821 tggcagttaa tcaggaaaca cctaagctct ctatagcgct taatggcatt gtactcacat
    26881 cgaatgatga gacttctttt gtcttaatta atgaggggag cgaacaaaag cgatactccc
    26941 tcaacgaagc ccttgagtca gcgccgggaa cgtttattag aaaaataaat aaaaccagcg
    27001 ttgtgtttga aactcacggg cattacgaaa aagtaactct ccatccaggg ctacctgaca
    27061 tcatcaagca gcctgattca gaaagtcaaa atgtactcgc tgattatatt atcgccacgc
    27121 ctatacgtga tggagaacag atatacgggc ttcgattgaa ccctcgtaag ggcctcaatg
    27181 catttaccac cagcttgcta caaccagggg atatcgccct caggatcaat aatctttcgc
    27241 tgacccaccc tgatgaggtt tcacaggcat taagtttact gctaactcaa caaagtgctc
    27301 agtttacaat tcgtcgcaac ggcgtacccc gcttgataaa tgtttccgtc ggggaactta
    27361 caggaatgaa tggactgcgt catgaaagga ctcaataaaa tcacctgctg cttgctggca
    27421 gcactactca tgccttgtgc aggacacgct gagaacgaac aatacggcgc gaacttcaat
    27481 aacgccgata tccgccagtt cgtggaaata gtgggtcagc atcttggcaa aacgatcctg
    27541 atcgaccctt cggtacaggg aaccatttcc gtacgcagta atgatacgtt tagccaacag
    27601 gagtactacc agttcttttt aagtattctt gatctttacg gttattccgt gatcacgctg
    27661 gacaatggtt ttctgaaagt ggttcgctca gctaatgtaa aaacatcgcc agggatgatt
    27721 gctgacagtt ctcgtccagg cgtaggtgat gagttggtca cccgaattgt accgcttgag
    27781 aacgttcctg ctcgtgacct ggcccccctg ctccgccaga tgatggatgc gggtagcgtc
    27841 ggtaatgttg tgcattatga accctccaac gttcttattc tgaccggtcg tgcctccacc
    27901 attaataaac tgattgaagt cataaagcgc gttgatgtca tcggcacaga gaagcagcaa
    27961 attattcatc tggaatatgc gtcagcggaa gatctcgccg agattcttaa tcaattaatc
    28021 agcgaaagcc acggtaaaag ccagatgcca gccctcctct ccgcgaagat tgtggcggat
    28081 aagcgaacca actctcttat catcagtgga ccggaaaaag cacgccagcg catcacttca
    28141 ttactgaaaa gccttgatgt cgaagagagc gaggaaggaa atacccgggt ttattacctg
    28201 aaatatgcta aagccacgaa tctggtggaa gtgctaaccg gtgtttccga aaagctgaaa
    28261 gatgaaaaag ggaatgcgcg taagccctcc tcttctggcg cgatggataa cgtcgccatt
    28321 accgccgatg aacagactaa ctctctggtc attaccgctg accagtccgt ccaggaaaaa
    28381 ctcgccacgg taattgcgcg tctggacatt cgccgtgcac aggtgctggt tgaggcaatc
    28441 atcgttgaag ttcaggatgg aaatggacta aacctcggcg tgcaatgggc gaataaaaac
    28501 gttggcgcac agcaatttac caataccgga ttaccgattt ttaacgctgc gcaaggtgtg
    28561 gctgattata aaaagaatgg tgggatcacc agcgcgaatc ctgcctggga tatgtttagc
    28621 gcctacaatg gcatggccgc aggcttcttc aatggcgact ggggagtact gcttaccgcg
    28681 ctggccagta acaataaaaa tgacatcctc gccaccccaa gcatcgtaac gctggataat
    28741 aaactcgcgt ccttcaacgt ggggcaggat gtgccggtgc tatccgggtc acagaccact
    28801 tcaggggata acgtctttaa taccgtcgaa cgcaaaacgg tggggacaaa actcaaagtt
    28861 actccgcagg tcaatgaagg cgacgcggtg ttgctcgaaa tagagcagga agtctccagc
    28921 gttgactctt cctctaactc gacgctcggc ccgacgttta atacccgtac tattcaaaac
    28981 gccgtgctgg tcaaaaccgg tgaaacggtg gtcctgggcg gattgctgga tgatttttct
    29041 aaagagcaag tgtcaaaggt tcctctgctt ggcgatattc ctttagtggg gcaactcttc
    29101 cgctatacct ccaccgagcg cgctaaacgc aacctgatgg tatttatccg tccgacgatt
    29161 atccgtgacg atgatgttta tcgctcactg tcaaaagaga aatacacccg ttaccgtcag
    29221 gagcaacaac agcggatcga cgggaaatca aaagcgctgg ttggctcgga agatttgccg
    29281 gtgctggatg aaaacacgtt caacagtcac gcccctgcgc catcgtcacg gtgaggcatt
    29341 catatgagaa ttcactcacc gtaccccgcc agttgggcgc tggcacaacg aattggttat
    29401 ctctattcag agggcgagat tatttatctc gccgatacgc cattcgagcg gttactcgat
    29461 attcaacgtc aggttggcca gtgccagacc atgaccagct tgtcacaggc tgattttgaa
    29521 gctcggctgg aagcggtatt ccatcagaat accggtgagt cgcaacagat tgcgcaggat
    29581 atcgatcaat ccgtcgatct tctctcgctt tcggaagaga tgcccgcaaa tgaagatctc
    29641 ctgaatgaag attcagcggc accggttatc cgcttgatca atgcgatttt gagtgaggcc
    29701 atcaaagaaa ccgcctctga tatccacatt gaaacctatg aaaaaacaat gtcgatccgt
    29761 tttcgcatcg acggcgtttt gcggacaatt ttacagccaa acaaaaaact ggcggcactg
    29821 cttatctccc gaattaaggt catggctcgt cttgatatcg ccgaaaaacg tattccacag
    29881 gatggaagaa ttagtttgcg tatcgggcga cgtaacatag atgtccgcgt atccacactg
    29941 ccgtccatct atggtgaacg cgccgtactc cgcctgctgg ataaaaacag cctccagctt
    30001 tcattgaaca acctggggat gacggcagcg gataagcagg atttagaaaa tctcattcag
    30061 cttccgcacg gtattatcct ggtgacaggg ccgacaggct ccggtaaaag caccacgctc
    30121 tacgccatcc tttcggcgct gaatactccc ggccgcaata ttctgacggt agaagatccc
    30181 gtggaatatg agctggaagg cattgggcaa acgcaggtga atacccgtgt ggatatgtct
    30241 ttcgctcgcg gcctgcgcgc catacttcgc caggatccgg atgtcgtcat ggtgggggaa
    30301 attcgtgata cagaaaccgc gcagattgcg gttcaggcct cgctcaccgg ccatctggta
    30361 ctctcaacac tccacactaa cagtgcatca ggcgcagtga cccggctccg cgacatgggc
    30421 gtcgaatcat tcctgctttc gtcttccctg gcagggatta tcgcgcaacg tctggttcgt
    30481 cgcctgtgtc cgcaatgccg acaattcacg cccgtatcac cccaacaagc gcagatgttt
    30541 aaatatcatc agctcgcggt gacaacaatt ggcactcccg taggctgccc tcattgccat
    30601 caatccggct atcaggggcg catggcgatc cacgaaatga tggtggtgac gccggaatta
    30661 cgggccgcta ttcatgaaaa tgtggatgaa caagcactgg agcgactagt ccggcaacaa
    30721 cacaaggcct taatcaaaaa tggcctgcaa aaagtgataa gcggtgacac ctcctgggat
    30781 gaggttatgc gcgtcgccag tgccacgctg gagagcgaag catgaattat cgctatcgcg
    30841 ccatgaccca ggatggtcaa aaattgcaag ggatcattga tgctaacgat gaacgtcagg
    30901 cacgactgcg gctgcgtgaa gaagggcttt tcctgctgga tattcgcccc caaaaaagtt
    30961 cgggagtaaa aacacgtcgc ccgaggatca gccatagtga actgacgctt ttcacccggc
    31021 agttggcaac cttaagcgca gcggcattac ccctggaaga gagccttgcc gtaatcggtc
    31081 aacaaagcag taataaacga ctgggtgacg tgttaaatca ggtacgcagc gccatccttg
    31141 aagggcatcc cctttccgat gcattacagc attttcccac gcttttcgat tcgctctatc
    31201 gtaccctggt aaaagcgggc gaaaagagcg ggctgctggc cccggtgttg gaaaagctgg
    31261 ctgattacaa tgaaaaccgg cagaaaatcc gcagcaagct cattcagtca ctgatctacc
    31321 cctgtatgct cactacggtg gcgattgggg tcgtgattat tctcctcact gctgtcgtgc
    31381 ccaaaattac cgaacagttc gtgcatatga agcagcaact gccgctgagt acacgcattc
    31441 ttttaggtct gagcgacacg ttgcaacgta tcggcccgac attattagcg acagtgttta
    31501 ttgtcgctgt aggtttctgg ctctggttaa aacgcggcaa taaccgccac cgttttcatg
    31561 ccatgttgct gcgcgttgcg ctcatcggcc cgctgatttg cgccattaac agcgcacgct
    31621 atctccgcac tttaagtatt ttgcaatcca gcggcgtccc tctgctggat gggatgagtt
    31681 tgtccaccga aagcctcaac aacctcgaaa ttcgccagcg tctggcaaat gcggcagaga
    31741 acgttcgcca gggtaacagc attcatcttt cgctggaaca aaccgcaatt ttcccgccga
    31801 tgatgctcta catggtggcc tctggcgaaa aaagcgggca gctcggcaca ttaatggtca
    31861 gagccgcaga taaccaggag acactccaac aaaatcggat cgccttaacg ctctccatct
    31921 tcgagccagc actcattatt acgatggcac tgatcgtcct gtttattgtc gtgtcggtac
    31981 tccaacctct tcttcaactt aactcaatga ttaattaagg aaagcatatg cgcgcaacgg
    32041 ataagcaacg cggttttaca ttactggaaa ttatggtggt gatcgtcatt atcggcgtac
    32101 ttgccagcct ggtggttcct aacctaatgg gcaataaaga aaaggcggat aagcaaaaag
    32161 ccgtcagcga tattgtggcg ctggaaaacg cccttgatat gtacaaactc gacaatcatc
    32221 actatccaac cacaaatcag gggcttgaat ccttagtaga agcgccgaca ctgccaccgc
    32281 tggccgcaaa ctataacaag gaaggttata tcaagcgtct gcctgccgat ccctggggca
    32341 atgattatgt cctcgttaat cctggtgaac atggtgcata cgatctgctt tcagcagggc
    32401 ccgatggtga aatgggaacc gaggacgaca tcaccaactg gggtttgagc aagaagaaaa
    32461 agtaagtcag cgatgaatca gcaacgcggg tttaccctgc tggagatgat gctggtgctg
    32521 gcgctggtcg ctatcacggc aagcgtggtg ctcttcacat atggccggga ggatgtcgcc
    32581 agcactcgtg cgcgcgaaac agcggcgcgg tttaccgctg cacttgaatt agccatcgac
    32641 cgcgccacgc tcagtggtca gcctgtcggt atccatttct ctgattcagc atggcgcatt
    32701 atggtaccgg gcaaaacacc atcagcctgg cgctgggttc cattacaaga agatgccgca
    32761 gacgagagcc aaaatgactg ggatgaagaa ctctcaattc atcttcagcc atttaaacct
    32821 gatgacagca accagccaca ggttgtgatt ctggccgacg gacaaatcac gcccttctct
    32881 ttgttgatgg ctaacgccgg gaccggtgag ccgctcctga cgttagtctg ttcaggctca
    32941 tggcccctgg atcaaacgct cgccagagat acccgcccat gaacaaacaa tcagggatga
    33001 cactgcttga agtcttactg gcgatgagta ttttcaccgc tgttgctctg actttaatga
    33061 gcagtatgca agggcaacga aatgccatcg agcgaatgcg taacgagacg ctggcattgt
    33121 ggatagcgga taaccagctt cagtcacaag attcattcgg cgaggaaaac acgtccagtt
    33181 ctggcaaaga gttaataaat ggcgaagagt ggaactggcg cagcgatatc cactcaagca
    33241 aagacggcac gcttctggaa cgcaccataa cggtgacatt acccagcggt cagacaacct
    33301 cgcttacgcg ttatcaaagc atcgataata aatccgggca ggcacaagat gattaatcgc
    33361 cagcagggtt tcacattgct ggaggtcatg gcggcgctgg cgattttctc aatgcttagc
    33421 gtgctggcgt ttatgatttt ttcgcaagct tccgagttgc atcaacgctc acagaaagaa
    33481 atccagcagt tcaatcagct acagcgcacc atcaccattc ttgataacga tctcctgcaa
    33541 ctggtcgccc ggaggaatcg gagtacggac aaaatcatgg tgttgggtga agaagctatt
    33601 tttaccacgc aaagtcgcga tccgctggct cctctcagtg aagcacaaac cttactcact
    33661 gttcactggt atctgcgaaa tcatacgctc taccgtgctg ttcgtacttc tgtggatggc
    33721 aggaaggatc aacccgccca ggcgatgctg gaacatgtcg agagctttct tctggaaagt
    33781 aacagcgggg aaagccagga acttcctctc tcagtcacgt tacatctgca gactcagcaa
    33841 tatggggggt tacagcgccg ttttgcatta cctgagcagt tagcgagaga agagtcgcca
    33901 gctcagacgc aggccgggaa taataaccat gaataatgaa caacgcggcg tcgcgctgct
    33961 cattgtactc atgttactgg cgctcatggc tgctctggca gcagacatga cgctcagttt
    34021 tcacagccag cttcagcgaa cccgccaggt aaaccatcat ctgcaacggc aatatgatat
    34081 tgaactggcg gagaaacttg cgcttgccag cctcacccag gacgttaaag ataacgacag
    34141 acagaccacg ttgcagcagt actgggcaca gccacaacag ttgcagctgg aagatggcaa
    34201 tacagtgaag tggcagttac gcgatgccca gcactgtttt aatctcaatg cgttagcaaa
    34261 aatctctgac gacccgctgg cttcccctga tttccccgcc caggtattca gtgcgctgct
    34321 gattaacgcc ggtatcgatc gcggaaacac cgatgagatc gtgcaatcaa tcgctgacta
    34381 tattgatgtc gatgactcac cacgctttca cggcgcagaa gatagctttt accaaagcca
    34441 gacgccgccc cggcatagtg ccaatcagat gctttttctg actggcgaat tacgtcagat
    34501 aaaaggcata accgaaaaca tctatcagcg gcttatcccg tatgtctgcg ttctcccgac
    34561 cacggaactt agcatcaatc ttaatatgct aacggagaac gatattccgc tcttcagagc
    34621 gttattcctc aataacatca cggatgctga cgctcgggtc ttattgcaaa aaaggccgag
    34681 ggaaggctgg ctaaccacgg atgcatttct ttactgggcg cagcaggatt tctccggtgt
    34741 gaagccactg gttgctcagg tgaaaaggca tctctttccc tatagccgct attttacgct
    34801 gagtacggaa agtatcagcg acgaacaatc ccagggatgg caaagccata tttttttcaa
    34861 ccgtaaacag cagagcgccc aaatctatcg gcgtacgctg caactctact aatcataagg
    34921 atcgtgatgc ctgaatcgtt gatggtcata cgttcttcct cgacgctgcg taagcattgg
    34981 gaatggatga cgttctccgc agatagcgta tcttcggtac atacgctcac ggacgatctt
    35041 ccgctggagt cgctggccga tcagcccggt gccggaaatg ttcatctttt gatcccacca
    35101 gagggccttt tatatcgttc cctcacgctg cccaacgcca aatacaaact caccgcacaa
    35161 acattacaat ggctggcaga ggagacgtta cccgacaaca cccaggactg gcactggacg
    35221 gttgtcgata aacaaaacga aagtgtcgag gtgataggca ttcagtcgga gaaactcagt
    35281 cgctatcttg agcgtttaca tactgccgga ctcaacgtga cgcgggtttt gccagatggc
    35341 tgctatcttc cctgggaagt agatagctgg actctggtta accagcaaac aagctggctc
    35401 attcgcagtg ccgcacatgc cttcaacgaa ctggatgaac actggttaca gcatcttgct
    35461 gcccagtttc cgcctgagaa tatgctttgt tatggtgtag tacctcacgg cgttgcagcg
    35521 gccaatccac ttatccagca tcctgaaata ccatcactga gtttgtattc tgccgatatt
    35581 gcattccagc gctatgacat gctgcatggt atttttcgta aacagaaaac tgtaagcaaa
    35641 tcgggaaaat ggctcgcccg cctggcagta agctgtctcg ttctcgccat tctttctttt
    35701 gttggcagcc ggagcatcgc gctctggcat acgcttaaga ttgaagatca acttcagcaa
    35761 caacagcaag aaacctggca acgttatttc ccgcagatca aacgcaccca caattttcgt
    35821 ttttacttta agcagcaact cgctcagcaa tatcctgaag ctgtgccgtt gctctatcat
    35881 ttacaaacac ttctgctgga acaccctgaa ctgcagttaa tggaggcgaa ctatagccag
    35941 aagcaaaagt cgctgacctt aaaaatgagt gctaagagtg aagctaatat cgatcgtttc
    36001 tgtgagttaa cacagtcctg gcttccgatg gaaaaaacag aaaaagatcc ggtcagtggt
    36061 gtatggacag taaggaactc agggaaatga ttaaatcatg gtgggcagaa aaatccacat
    36121 cggaaaaaca gatcgttgcg gcactggcgg ttctctcgct cggcgttttt tgttggcttg
    36181 gggtgataaa accgatagat acctacattg cagagcatca gtcccacgcg caaaaaatta
    36241 agaaggacat caaatggatg caggatcaag cgagcaccca tggtttactc ggtcatcctg
    36301 cgcttacgca gcccatcaaa aatatccttc tcgaggaagc aaaacgtgag aatttggcta
    36361 tcacgctgga aaacggcccg gacaatactc tgacaattca tcctgtcaca gctcccctcg
    36421 aaaacgtctc ccgctggctc actacggcac aggtaacata cggtattgtt attgaagacc
    36481 ttcagtttac tcttgccgga aacgaagaga tcaccctcag gcatttgtcc ttcagggagc
    36541 aacaataatg acaatgctac tgccgctctt cattctggtt ggttttattg caggttattt
    36601 tgttaatgcc atcgcctatc acctctcgcc gttggaggat aaaacggcgt taacgtttcg
    36661 ccaggtattg gttcatttca ggcaaaaaaa atatgcctgg catgatacag tgcccctgat
    36721 actttgtgtt gctgctgcta tcgcctgcgc cctggcacct ttcacgccca tcgtgactgg
    36781 cgcactcttt ctctatttct gtttcgtact cacgctcagt gttattgatt ttcgcactca
    36841 gctcctgccc gacaaactca ccttaccgct gctctggctt ggcttggtat ttaatgcgca
    36901 gtatggatta attgatttac atgatgcggt ttacggcgcg gtagcgggct atggggtgct
    36961 gtggtgtgtt tactggggcg tctggttagt ttgtcacaaa gagggattgg gctacggtga
    37021 tttcaagcta ctggccgctg caggcgcatg gtgtggctgg caaacgttgc caatgatact
    37081 gctgattgcc tcgctgggtg gcattggtta cgccatcgtt tcacaacttc tgcaacgccg
    37141 gactataacc actatcgcat tcggcccgtg gcttgcgctc ggcagcatga taaacctggg
    37201 gtatctggcc tggatctctt attaaccggg agggttctcc ctcccgacac ggctcaacct
    37261 tcttcgcgga tctgtgcttg cagataattt tgcaggccca tcttctgaat cagatcaagt
    37321 tccgtttcca gccagtcgat atggccttct tcatcacgca aaatttctat catcatatcg
    37381 cggctgacgt aatcatgaac gctatcggca taaccaattg cctcacgcaa attcttcgcg
    37441 ccatccagct caagtgccag atcagaacgc agcatttcct caacatcttc accaatgttc
    37501 agtttgccca ggtcctgtaa gtttggaaga ccttccagaa aaagaatgcg ctcaatataa
    37561 cgatcggcgt gtttcatctc atcaatggat tcatgatact ccacatcatt gagacgtttg
    37621 agaccccagt ttttaaacat tcgggcatgg agaaagtact gattgattgc gacaagctca
    37681 tttcccaaca gtttgttgag ataatttata actttagtat cacctttcat tttttgactc
    37741 cttcgcttcc actctttgaa gagtagaacg gcttacgagt aagtcaaaaa acacactccg
    37801 tttatgcgga ctccttaaac tccggcagct gcattaattc atcctccatc acttcacgcg
    37861 cggcccggac acatttaccg cactgattgc cgaccggaat aaattttttt aattgctgga
    37921 acgagtgagg ggaaaactgg cgcacagcct gacgaatttt tttatcgctg ataccattac
    37981 aaagacaaac gtacatagag actcccgtat actttcttca aaaataaatg aaaatagttc
    38041 ttatttcaat tacggaaaga ctctttttta agcaaagaat agaaatatga ataaaaataa
    38101 tgggctacca aaagtagccc attgacaaaa aatgcggcga tactggaagg tatcgccaac
    38161 acatttattg cttagtaaac ggcgcgaaga tttcgctaaa tgcgtacttc ggtgcctgtt
    38221 ctttagtcag gccgtggaat tccggagaca ggttagtgcc gcccggcagg tcgcgcgcga
    38281 ttgaccagat accaaccata ccgagattac gcttctgcgc atcctgcatg accagacgag
    38341 catcagagag atagaacacc tcgccctgaa cgtcgttcac gccaaccatc ggcgtggtac
    38401 ccatcatagc gtcaatttct gcatcgctct tattgggatg gaggcctttc aattgtgaat
    38461 gcaggttggc aatcgcagac gttgcacact taccgtgaat gttctggcct tcggtatttg
    38521 cagactgaca aatcgcgtta ccgtagtcca ttgtcatcac gttcacaccc gccagctcaa
    38581 cacctttcgc tttggcatcg ctcaggacat tcatcccttc cggcgtcagg tcagtcggca
    38641 gaattggcaa ggtgtaccag atagcaatat ctttgccttc tgacttccat ttatcctgca
    38701 ctttcttcac agcaaggtta cgacgttcaa tagatgcctg atccgcaacc caggtgcctt
    38761 cgatatcgaa gtccaggact ttgaggttca ggttatcaac gatgtcataa taatgctgca
    38821 tcagatcgtc tacgttctta caggaagcag ccagcggagc gttgttagca ccaccgatag
    38881 acagcatcac atcgccgcca gcctcacgca gagctttgat tttgctgtac tgagcgtaat
    38941 tctgcatacc gtaagcggta ccccatgtcg gcagacaggt gttcgcatct ttactcacca
    39001 caaacgccag cgtgaagtgg ttgacgttat gattcttagc cagcgcagcc agatccggga
    39061 tcgtattcag cgtaaagtcg acatacggtg cataaacgtg tttcggccac gctttcttcg
    39121 gcgtacctac gcgctctttg gttccggtcc agtcaacaaa aacacgccac gggttgctgt
    39181 cagaaggaga aactttctgc actttactct gagaaatgta gttcacaccg ttaaagcgaa
    39241 tcagcgtatc gctggcataa agcgtttctg gattaaactg cggcgcatta ttcagctctt
    39301 cgttgctata gctctgagcc ttacctaacg gcttccacgg gcggctattg ctaccggtgg
    39361 cgttttggtt cgccaccaga gcagggttgt cactttgcgt ccagaacagc gcttcataag
    39421 cctgcccatc aacaacaacg cgatcacctt tcacgtacac agtggatgcg gaccatgctt
    39481 tcgccggttc gtatttcttc cacgggttat cgccgcccgg gacaaagccc catgcgtctt
    39541 gatcgacaga agttttataa tgtgcatcgt tataatctac gatgctgtcc gcgctgtacg
    39601 ctttgctggc ctggaaacca tccgcaacaa tgacgccgcc gttatcaatt tcacaggtag
    39661 tcgggttacc gtactgactc aattccgcag cggtagctgt acgctcgaga cgccatgggt
    39721 tattggagtt ttcagcgctg gtaccccgtg ggcaatcttt agacccaacc caccaggcgt
    39781 tcttgtaaac attaccattg aaaataacat ggtaaatttc gctaccttcc tggccgctcc
    39841 acgcttgcaa tgagtaatcg ttaacgctat ccgctggtgt tgatggctcg ctgttatccg
    39901 gagttggggt caccggtgtt tccggagttg gatcaaccgg agtcacagca ccgccattat
    39961 tatccggctt aacggaacag gagccagggt taccatactg gctgatttct gttgccgttg
    40021 ccgcgcgaac ataacgccat gggttactgg catcgttttc tttcgcatcg cctgggcaat
    40081 ttgccgcgcc tacccaccag gcgttcttat aaatgccgcc gttatagata acgtaccatg
    40141 tagaagaacc ttcctgacct ttccaggcta ctacagcata gttgtcgttt gacttatcag
    40201 ctggggctgg ctgaacatca ggagccggtt taacgtccgg tgccggtttc acatccggtg
    40261 aaggctgtgg tgctgaagta caggactgtg gattactggt ttctgagatt tccgttgccg
    40321 tagcggcacg aacataacgc catgggttgc tggcatcatt gcttttcgca tcacccggac
    40381 agttagaaga ggctacccac caggcatttt tatataccgc accattaaag acgacatacc
    40441 aggtctgacc gccctgctgt ttattccagg caactacaga agaattagac ggaacagtgc
    40501 cctgtgctgg tgtagccgaa ccgccattag ccggcgtatt ggatgcaggc gtatttgaat
    40561 ttgaagaaga tgagctgccg ctcttttcgc aggaaagtgt attgccaaac tgactaattt
    40621 cagcagctgt tgcggtacgc tttaaacgcc acgggttagt tgcatcattt gctttcgctt
    40681 ttcccgggca atttgtagaa gaaacccacc aggcattttc ataaattttg ccatcgaaaa
    40741 taacctgata tttattacca ccttgttggt tattccatgc ttccattgcc aatgctggca
    40801 gagcggaaca caccagcccc ataccaatca tagatttagt aaatatattt aatttcatta
    40861 taatcccttg tgacgtaaaa actgcaaaac aaaagtccta cgcaggaatt atttacgttt
    40921 tacgagaacc cttcaatatg aattaaatta cggcattaaa aataagaaaa aagcctgaca
    40981 aatgaagcat tt
//
LOCUS       DACAOP010000034        39994 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.034, whole genome shotgun sequence.
ACCESSION   DACAOP010000034 DACAOP010000000
VERSION     DACAOP010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39994
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.034"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..85
                     /locus_tag="IT892_001993"
     CDS             <1..85
                     /locus_tag="IT892_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP3135216.1"
                     /translation="QVVRGVIIVVAVLANILLTQRSSKAKR"
     gene            118..1212
                     /locus_tag="IT892_001994"
     CDS             118..1212
                     /locus_tag="IT892_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAP3135217.1"
                     /translation="MKINRIVNEGFMKTMLAAYLPGNSTVDLREVAVPTPGINQVLIK
                     MKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFINGHEPCGQIVAMGQGCRHFKEGDR
                     VLVYHISGCGFCPNCRRGFPISCTGKGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
                     YEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDM
                     LPERLAMAKQLGVMDHGYLATTEGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTA
                     DWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCAHDLTDWKLWPRNAI
                     THRFSLEQAGDAYALMASGKCGKVVINFPD"
     gene            1224..2096
                     /locus_tag="IT892_001995"
     CDS             1224..2096
                     /locus_tag="IT892_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="HAP3135218.1"
                     /translation="MTIYTLSHGPLKLDVSDRGGVIEGFWRDATPLLRPGKKNGVATD
                     ASCFPLVPFANRVSGNRFVWQGREYQLQPNVEWDAHYLHGDGWLGQWQCVSRSEDSLC
                     LVYEHRSGVYHYRVSQAFHLTADTLTVTLSVTNQGAETLPFGTGWHPYFPLSPQTRTQ
                     AQASGYWLEREQWLAGEFCEQLPQELDFSQLAPLPHQWVNNGFAGWNGQARIEQPQEG
                     YAIIMETTPPAPCYFIFVSDPAFDKGYAFDFFCLEPMSHAPDDHHRPEGGDLIALAPG
                     ESTTSEMSLRVALL"
     gene            complement(2144..2566)
                     /locus_tag="IT892_001996"
     CDS             complement(2144..2566)
                     /locus_tag="IT892_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311436.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HAP3135219.1"
                     /translation="MNSLRYFDFGAARPVLLLIARIAVILIFIIFGFPKMMGFDGTVQ
                     YMASLGAPMPMLAAIIAVVMEVPAAILIVLGFFTRPLAVLFIFYTLGTAIIGHHYWDM
                     TGDAVGPNMINFWKNVSIAGAFLLLAITGPGAISLDRR"
     gene            complement(2663..3865)
                     /locus_tag="IT892_001997"
     CDS             complement(2663..3865)
                     /locus_tag="IT892_001997"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylpropionate dioxygenase ferredoxin
                     reductase subunit"
                     /protein_id="HAP3135220.1"
                     /translation="MKEKTIIIVGGGQAAAMAAALLRQQGFSGELHLFSDEQHLPYER
                     PPLSKSMLLEDSPQLQSVLPAHWWQENNVHLHSGVTIKTLGRDTQELVLANGESWHWD
                     QLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELA
                     ASATQRGCKVTVIELAASVMGRNAPPPVQRYLLPRHQQAGVRILLNNAIEHVVDGEKV
                     ELTLQSGETLRADVVIYGIGISANDQLAREANLDTANGIVIDEACRTCDPAIFAGGDV
                     AIIRLDNGALHRCESWENANNQAQIAASAMLGLPLPRLPPPWFWSDQYSDNLQFIGDM
                     RGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRPIRKWIQSGKTFDAKRLTD
                     ENIALKSL"
     gene            complement(3875..4687)
                     /gene="hcaB"
                     /locus_tag="IT892_001998"
     CDS             complement(3875..4687)
                     /gene="hcaB"
                     /locus_tag="IT892_001998"
                     /EC_number="1.3.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-(cis-5,6-dihydroxycyclohexa-1,
                     3-dien-1-yl)propanoate dehydrogenase"
                     /protein_id="HAP3135221.1"
                     /translation="MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVA
                     SLRQRFGEHILAVEGNVTCYADYQRAVNQILTRSGKLDCFIGNAGIWDHNASLVNTPA
                     ETLETGFHELFNVNVLGYLLGAKACAPALIASEGSMIFTLSNAAWYPGGGGPLYTASK
                     HAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALRQSETSIMQSLTPEKIAAIL
                     PLQFFPQPADFTGPYVMLASRRNNRALSGVMINADAGLAIRGIRHVAAGLDL"
     gene            complement(4684..5004)
                     /locus_tag="IT892_001999"
     CDS             complement(4684..5004)
                     /locus_tag="IT892_001999"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-phenylpropionate/cinnamic acid
                     dioxygenase ferredoxin subunit"
                     /protein_id="HAP3135222.1"
                     /translation="MNRIYACPVADVPEGEALRIDTSPVIALFNVGGEFYAINDRCSH
                     GNASMSEGYLEDDATVECPLHAASFCLKTGKALCLPATDPLTTYPVHVDGGDIFIDLP
                     EAQP"
     gene            complement(5004..5522)
                     /locus_tag="IT892_002000"
     CDS             complement(5004..5522)
                     /locus_tag="IT892_002000"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate/cinnamic acid dioxygenase
                     subunit beta"
                     /protein_id="HAP3135223.1"
                     /translation="MSAQVSLELHHRISQFLFHEASLLDDWRFRDWLAQLDEEIRYTM
                     RTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNC
                     QVSETDIPNVFAVRVNYLLYRAQKERDETFYVGTRFDKVRRLEDGNWRLLERDIVLDQ
                     AVISSHNLSVLF"
     gene            complement(5519..6880)
                     /locus_tag="IT892_002001"
     CDS             complement(5519..6880)
                     /locus_tag="IT892_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate/cinnamic acid dioxygenase
                     subunit alpha"
                     /protein_id="HAP3135224.1"
                     /translation="MTTPSDLNIYQLIDTQNGRVTPRIYTDPDIYQLELERIFGRCWL
                     FLAHESQIPKPGDFFNTYMGEDAVVVVRQKDGSIKAFLNQCRHRAMRVSYADCGNTRA
                     FTCPYHGWSYGINGELIDVPLEPRAYPQGLCKSHWGLNEVPCVESYKGLIFGNWDTSA
                     PGLRDYLGDIAWYLDGMLDRREGGTEIVGGVQKWVINCNWKFPAEQFASDQYHALFSH
                     ASAVQVLGAKDDGSDKRLGDGQTARPVWETAKDALQFGQDGHGSGFFFTEKPDANVWV
                     DGAVSSYYRETYAEAEQRLGEVRALRLAGHNNIFPTLSWLNGTATLRVWHPRGPDQVE
                     VWAFCITDKAASDEVKAAFENSATRAFGPAGFLEQDDSENWCEIQKLLKGHRARNSKL
                     CLEMGLGQEKRRDDGIPGITNYIFSETAARGMYQRWADLLSSESWQEVLDKTAAYQQE
                     VMK"
     gene            7016..7906
                     /gene="hcaR"
                     /locus_tag="IT892_002002"
     CDS             7016..7906
                     /gene="hcaR"
                     /locus_tag="IT892_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HcaR"
                     /protein_id="HAP3135225.1"
                     /translation="MELRHLRYFVAVAQALNFTRAAEKLHTSQPSLSSQIRDLENCVG
                     VPLLVRDKRKVALTAAGECFLQDALAILEQAENAKLRARKIVQEDRQLTIGFVPSAEV
                     NLLPKVLPMFRLRQPDTLIELVSLITTEQEEKIRRGELDVGLMRHPVYSPEIDYLELF
                     DEPLVVVLPVDHPLAHEKEITAAQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNI
                     VQVATNILVTMNLVGMGLGVTLIPGYMNNFNTGQVVFRPIAGNVPSIALLMAWKKGEM
                     KPALRDFIAIVQERLASVTA"
     gene            8066..9205
                     /locus_tag="IT892_002003"
     CDS             8066..9205
                     /locus_tag="IT892_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate MFS transporter"
                     /protein_id="HAP3135226.1"
                     /translation="MVLQSTRWLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLL
                     LGAGLIARFLGSLLIAPRVSDPSRLISALRVLALLTLLFAVAFWAGAHVAWLMLVMIG
                     FNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVTMFDYRVIL
                     ALLTLGVASMLLGFLIRPTIQPQGASRQQESAGWSAWLALVRQNWRFLACVCLLQGAH
                     AAYYGFSAIYWQAAGYSASAVGYLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAIC
                     GVVRWGIMGATTAMPWLIVVQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVA
                     MGGSIAIMTVFAGFLYQYLGHGVFWVMALVALPAMFLRPKVVPSC"
     gene            complement(9197..10477)
                     /gene="csiE"
                     /locus_tag="IT892_002004"
     CDS             complement(9197..10477)
                     /gene="csiE"
                     /locus_tag="IT892_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase inducible protein CsiE"
                     /protein_id="HAP3135227.1"
                     /translation="MMPTLAPPSVLSAPQRRCQILLTLFQPGLTATTATFSELNGVDD
                     DIASLDISETGREILRYHQLTLTTGYDGSYRVEGTVLNQRLCLFHWLRRGFRLCPSFI
                     TSHFTPALKSELKRRGIARNFYDDTNLQALVNLCSRRLQKRFETRDIHFLCLYLQYCL
                     LQHHAGITPQFNPLQRRWAESCLEFQVAQEIGRHWQRRALQPVPPDEPLFMALLFSML
                     RVPDPLRDAHQRDRQLRQSIKRLVNHFRELGNVRFYDEQGLCDQLYTHLAQALNRSLF
                     AIGIDNTLPEEFARLYPRLVRTTRAALAGFESEYGVHLSDEESGLVAVIFGAWLMQEN
                     DLHEKQIILLTGNDSEREAQIEQQLRELTLLPLNIKHMSVKVFLQTGAPRGAALIIAP
                     YTMPLPLFSPPLIYTDLTLTTHQQEQIRKMLESA"
     gene            complement(10668..11522)
                     /locus_tag="IT892_002005"
     CDS             complement(10668..11522)
                     /locus_tag="IT892_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417029.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP3135228.1"
                     /translation="MALPVNKRVLKILFILFVVAFCIYLIPRIAINFFYYPDDKIYGP
                     DPWSAESVEFTAKDGTRLHGWFIPSATGPAENAIATIIHAHSNAGNMSAHWPLVSWLP
                     ERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
                     NILDVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIP
                     LLLIHGKADHVIPWQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFI
                     LSALNPQN"
     gene            complement(11667..12470)
                     /gene="suhB"
                     /locus_tag="IT892_002006"
     CDS             complement(11667..12470)
                     /gene="suhB"
                     /locus_tag="IT892_002006"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-1-monophosphatase"
                     /protein_id="HAP3135229.1"
                     /translation="MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVD
                     KAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVS
                     IAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
                     AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGEL
                     LVREAGGIVSDFTGGHNYMLTGNIVAGNPRVVKAMLANMRDELSDALKR"
     gene            12589..13329
                     /gene="trmJ"
                     /locus_tag="IT892_002007"
     CDS             12589..13329
                     /gene="trmJ"
                     /locus_tag="IT892_002007"
                     /EC_number="2.1.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ"
                     /protein_id="HAP3135230.1"
                     /translation="MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDS
                     QAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVA
                     EAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
                     LATQENGEQVEHEETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTR
                     ARPESQELNILRGILASIEQQNKGNKAE"
     gene            13599..14087
                     /gene="iscR"
                     /locus_tag="IT892_002008"
     CDS             13599..14087
                     /gene="iscR"
                     /locus_tag="IT892_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HAP3135231.1"
                     /translation="MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQ
                     LFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGD
                     KCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKL
                     RA"
     gene            14199..15413
                     /gene="iscS"
                     /locus_tag="IT892_002009"
     CDS             14199..15413
                     /gene="iscS"
                     /locus_tag="IT892_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311423.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP3135232.1"
                     /translation="MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFG
                     WQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKT
                     EHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVV
                     QDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYV
                     RRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNR
                     LWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLE
                     PSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQ
                     GVDLNSIEWAHH"
     gene            15441..15827
                     /gene="iscU"
                     /locus_tag="IT892_002010"
     CDS             15441..15827
                     /gene="iscU"
                     /locus_tag="IT892_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HAP3135233.1"
                     /translation="MAYSEKVIDHYENPRNVGSFDNNDENVGSGMVGAPACGDVMKLQ
                     IKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIAEELELPPV
                     KIHCSILAEDAIKAAIADYKSKREAK"
     gene            15844..16167
                     /gene="iscA"
                     /locus_tag="IT892_002011"
     CDS             15844..16167
                     /gene="iscA"
                     /locus_tag="IT892_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HAP3135234.1"
                     /translation="MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEF
                     VDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCG
                     ESFHV"
     gene            16263..16778
                     /gene="hscB"
                     /locus_tag="IT892_002012"
     CDS             16263..16778
                     /gene="hscB"
                     /locus_tag="IT892_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone HscB"
                     /protein_id="HAP3135235.1"
                     /translation="MDYFTLFGLPACYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQ
                     LAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREEL
                     DEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTVRKLRFLDKLRSS
                     AEQLEEKLLDF"
     gene            16795..18645
                     /gene="hscA"
                     /locus_tag="IT892_002013"
     CDS             16795..18645
                     /gene="hscA"
                     /locus_tag="IT892_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HAP3135236.1"
                     /translation="MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETL
                     ADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPH
                     LPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYF
                     DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISIL
                     RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKI
                     ALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVM
                     VGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVI
                     PLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRS
                     LARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSE
                     IASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSTAERQVIDDAA
                     AHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV"
     gene            18647..18982
                     /gene="fdx"
                     /locus_tag="IT892_002014"
     CDS             18647..18982
                     /gene="fdx"
                     /locus_tag="IT892_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015683702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HAP3135237.1"
                     /translation="MPKIVILPHQDLCPDGAVLEANSGETILDVALRNGIEIEHACEK
                     SCACTTCHCIVREGFDSLPESSEQEDDMLDKAWGLEPESRLSCQARVTDEDLVVEIPR
                     YTINHAREH"
     gene            18994..19194
                     /gene="iscX"
                     /locus_tag="IT892_002015"
     CDS             18994..19194
                     /gene="iscX"
                     /locus_tag="IT892_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HAP3135238.1"
                     /translation="MGLKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICDLEDFDD
                     DPQASNEKILEAILLVWLDEAE"
     gene            19253..20536
                     /gene="pepB"
                     /locus_tag="IT892_002016"
     CDS             19253..20536
                     /gene="pepB"
                     /locus_tag="IT892_002016"
                     /EC_number="3.4.11.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417018.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase PepB"
                     /protein_id="HAP3135239.1"
                     /translation="MTEEMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLI
                     QRAARKIDGLGIKHVQLSGEGWDADRCWTFWQGYKAPKGTRKVEWPDLDDAQRQELDN
                     RLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLRDQGYMGL
                     HTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSD
                     MGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNT
                     DAEGRLVLADGLIDASAQKPELIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLAS
                     AAQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGW
                     LHIDCSATYRKSPVEQWSAGATGLGVRTIANLLTA"
     gene            20655..21431
                     /gene="sseB"
                     /locus_tag="IT892_002017"
     CDS             20655..21431
                     /gene="sseB"
                     /locus_tag="IT892_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311415.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="HAP3135240.1"
                     /translation="MSETKNELEDLLEKAATEPAHRPAFFRTLLESTVWVPGTAAQGE
                     AVVEDSALDLQHWEKEDGTSVIPFFTSLEALQQAVEDEQAFVVMPVRTLFEMTLGETL
                     FLNAKLPTGKEFMPREISLLIGEEGNPLSSQEVLEGGESLILSEVAEPPAQMIDSLTT
                     LFKTIKPVKRAFICSIKENEEAQPNLLIGIEADGDIEEIIQAAGSVATDTLPGDEPID
                     ICQVKKGEKGISHFITEHIVPFYERRWGGFLRDFKQNRII"
     gene            complement(22191..23036)
                     /gene="sseA"
                     /locus_tag="IT892_002018"
     CDS             complement(22191..23036)
                     /gene="sseA"
                     /locus_tag="IT892_002018"
                     /EC_number="2.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-mercaptopyruvate sulfurtransferase"
                     /protein_id="HAP3135241.1"
                     /translation="MSTTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLN
                     GHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAP
                     RAWWMLRTFGVEKVSILGGGLAGWQRDDLLFEEGAVELPEGEFNAAFNPEAVVKVTDV
                     LLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGAFNVPWTELVREGELKTTDE
                     LDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLP
                     VEPVK"
     gene            23243..28201
                     /gene="yfhM"
                     /locus_tag="IT892_002019"
     CDS             23243..28201
                     /gene="yfhM"
                     /locus_tag="IT892_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha2-macroglobulin"
                     /protein_id="HAP3135242.1"
                     /translation="MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSEN
                     VSSAKLSAPERQKLAQQSAGKALTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIH
                     VVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDYEKTIT
                     TRDIQPSVGFASRGSLLPGKVIEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRN
                     SLANWQSEKLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAG
                     RYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAAQQGIEVSLLNEKGQTLTQA
                     TSDAQGHVQLENDKNAALLLARKDGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFG
                     PRDLYRPGETVILNGLLRDADGKALPDQPIKLDVIKPDGQVLRSVVSQPENGLYHFTW
                     PLDSNAATGMWHIRANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVRFSV
                     VGYYLYGAPANGNTLQGQLFLRPLREAVSALPGFEFGDIAAENLSRTLDEVQLTLDDK
                     GRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQVIWPADALPGIRPQFASK
                     SVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSE
                     DEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAG
                     YSWQDNSDGSGAVRPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWW
                     QEIDVPAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDEN
                     RRLDLALETPTKMRPNQPLTVKIKASNKNGEMPKQVNVLVSAVDSGVLNITDYVTPDP
                     WQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVAQQA
                     LPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADDFGSNESKVIVAAPVIAELNMPRF
                     MASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSVSPAAVELAPGVRTTLFIPVR
                     ALPGYGDGEIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAI
                     PADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAA
                     QLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLV
                     RAGEQGYSVPTDVINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQ
                     KAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRSEEAIALALKTPRNDERKWL
                     GDYGSPLRDNALMLSLLEENKLLPDEQNTLLNTLSQQAFGERWLSTQESNALFMAART
                     IQDLPGKWQAQTSFSTEPLTGEKAQNSNLNSDQLAALQVTNSGDQPLWLRVDASGYPQ
                     SAPLPANNVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLPA
                     GLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPVT
                     LVYLARAVTPGTYQVPQPMVESMYVPQWRATGAAEDLLIVRP"
     gene            28202..30514
                     /gene="pbpC"
                     /locus_tag="IT892_002020"
     CDS             28202..30514
                     /gene="pbpC"
                     /locus_tag="IT892_002020"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417014.1"
                     /note="penicillin-binding protein 1C; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase PbpC"
                     /protein_id="HAP3135243.1"
                     /translation="MPRLLTKRGCWITLAAAPFLLFLAAWGADKLWPLPLHEVNPARV
                     VVAQDGTPLWRFADAEGIWRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARA
                     AWQDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLY
                     LNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQTPSRLRPDRWPERAEAA
                     RNKVLERMAVQGVWSREQVKESREEPIWLAPRQMPQLAPLFSRMMLGKSKSDKIVTTL
                     DAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHTDMRVRGWVGSVDLNDDSRFGHVDMV
                     NAIRSPGSVLKPFVYGLALDEGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPISMSEA
                     LVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPNGAAPNLSLILGGAGAKLGDMAA
                     AYTAFARHGKAGKLRLQPDDPLLERPLMSSGAAWIIRRIMADEAQPLPDGALPRVAPL
                     AWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNILLS
                     RSANLPEDPRPDSVSRGVICWPGGQSLPEGDGNCRLRLATWLLDGSQPPTLLLPEQEG
                     INGIRFPIWLDENGKRVAADCPQARQEMINVWPLPLEPWLPASEHRAVRLPPASTICP
                     PYGHDAQLPLQLTGVRDGAIIKRLPGAAEATLPLQSSGGAGERWWFLNGEPLTERGRN
                     VTLHLTDKGDYQLLVMDDVGQIATVKFVMQ"
     gene            30663..31094
                     /gene="ndk"
                     /locus_tag="IT892_002021"
     CDS             30663..31094
                     /gene="ndk"
                     /locus_tag="IT892_002021"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAP3135244.1"
                     /translation="MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTV
                     EQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGT
                     LRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR"
     gene            31244..32398
                     /gene="trmG/rlmN"
                     /locus_tag="IT892_002022"
     CDS             31244..32398
                     /gene="trmG/rlmN"
                     /locus_tag="IT892_002022"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA
                     large subunit methyltransferase RlmN"
                     /protein_id="HAP3135245.1"
                     /translation="MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQ
                     VMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQ
                     RVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVG
                     AAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPA
                     LDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVT
                     IEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVL
                     MSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV"
     gene            32683..33696
                     /gene="rodZ"
                     /locus_tag="IT892_002023"
     CDS             32683..33696
                     /gene="rodZ"
                     /locus_tag="IT892_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HAP3135246.1"
                     /translation="MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTV
                     RDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSL
                     GKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELSSNSEQ
                     GQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPAVTAPAPAVDPQQNAVVSPSQANV
                     DTAATPAPTATTTPDGAAPLPTDQAGVTTPAADPNALVMNFTADCWLEVTDATGKKLF
                     SGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQS
                     PAQ"
     gene            33723..34841
                     /gene="ispG"
                     /locus_tag="IT892_002024"
                     /gene_synonym="gcpE"
     CDS             33723..34841
                     /gene="ispG"
                     /locus_tag="IT892_002024"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HAP3135247.1"
                     /translation="MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEAT
                     VNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGV
                     DCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
                     AMRHVDHLDRLNFEQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAV
                     KSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQ
                     EFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGV
                     RKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK"
     gene            34952..36226
                     /gene="hisS"
                     /locus_tag="IT892_002025"
     CDS             34952..36226
                     /gene="hisS"
                     /locus_tag="IT892_002025"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAP3135248.1"
                     /translation="MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLP
                     IVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
                     QRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEH
                     VTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQAL
                     LNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSL
                     GSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLV
                     ASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEV
                     ANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG"
     gene            36244..36864
                     /locus_tag="IT892_002026"
     CDS             36244..36864
                     /locus_tag="IT892_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfgM family protein"
                     /protein_id="HAP3135249.1"
                     /translation="MEIYENENDQVEAVKRFFAENGKALAVGVILGVGALIGWRYWNS
                     HQVDSARSASLAYQNAVTAVSEGKPDSIPAAEKFAAENKNTYGALASLELAQQFVDKN
                     ELEKAAAQLQQGLADTSDENLKAVINLRLARVQVQLKQADAALKTLDTIKGEGWAAIV
                     ADLRGEALLSKGDKQGARSAWEAGVKSDVTPALSEMMQMKINNLSI"
     gene            36875..38053
                     /gene="bamB"
                     /locus_tag="IT892_002027"
     CDS             36875..38053
                     /gene="bamB"
                     /locus_tag="IT892_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HAP3135250.1"
                     /translation="MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTP
                     TTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDG
                     WFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDG
                     LVLIHTSNGQLQALNETDGAVKWTVNLDMPSLSLRGESAPATAFGAAVVGGDNGRVSA
                     VLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQ
                     IMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYN
                     GNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
                     "
     gene            38171..39643
                     /gene="der"
                     /locus_tag="IT892_002028"
     CDS             38171..39643
                     /gene="der"
                     /locus_tag="IT892_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417006.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAP3135251.1"
                     /translation="MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGR
                     AEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAI
                     AKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
                     PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTL
                     TNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVI
                     KTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQV
                     KETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAV
                     EDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMG
                     TPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK"
     gene            39706..39921
                     /locus_tag="IT892_002029"
     CDS             39706..39921
                     /locus_tag="IT892_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001592478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135252.1"
                     /translation="MALNCPTCKTPLERNGETAHCATCDKDFTVQALCPECHQPLQVL
                     KACGAVDYFCQHGHGLISKKRVEFVIA"
BASE COUNT         9535 a         9941 c        11162 g         9356 t
ORIGIN      
        1 gcaggtggtg cgcggcgtca tcatcgtggt ggcggtgctg gcgaatatct tgctgaccca
       61 gcgtagcagt aaagcgaaac gctaaacctt aacgcccctg gcgcgggtgc ggcagggatg
      121 aaaattaatc gtattgttaa tgagggattt atgaaaacga tgctggcagc ttatttacca
      181 ggaaattcga ccgtcgatct gcgggaagtt gcggtgccga cgccggggat taaccaggta
      241 ctgatcaaaa tgaaatcctc cgggatttgc ggaagtgatg tccactatat ctatcatcaa
      301 caccgtgcca cggcagcggc acccgataaa ccgttatacc agggatttat caacggtcat
      361 gaaccgtgcg ggcagattgt ggcgatgggg caaggctgcc gccattttaa agagggcgac
      421 cgcgtgctgg tgtatcacat ttctggctgt ggtttttgcc cgaactgccg ccgcggcttt
      481 cctatctctt gtactggcaa aggaaaagcg gcttacggct ggcagcgtga cggcggccat
      541 gctgaatacc tgctggcaga agaaaaagat ctgatcctgc tcccggacgc gctgagctat
      601 gaagatggtg cgtttatcag ttgcggcgtt ggtacagcgt atgaagggat tttgcgcggc
      661 gaagtttccg gcagtgataa cgtgctggtg gtcggtctgg ggccggtcgg catgatggcg
      721 atgatgctgg cgaaaggtcg cggtgcaaaa aggatcatcg gcgttgatat gctgccggaa
      781 cgtctggcga tggcgaaaca gttaggggtg atggatcacg gctatttagc aaccaccgaa
      841 ggtctgccgc agattatcgc cgaactcacc cacggtggcg cggatgttgc gctcgattgt
      901 tccggtaatg ccgcaggtcg cttactggcg ttgcaatcca ctgctgactg gggacgggtg
      961 gtttacatcg gggaaaccgg aaaagtggag ttcgaggtta gcgctgatct gatgcatcat
     1021 caacggcgga ttattggctc ctgggtgacc agtctattcc atatggaaaa atgcgcccac
     1081 gatttaacgg actggaaact gtggccgcgt aatgccatta cccatcgctt ctcactggaa
     1141 caggcaggag atgcctatgc gctgatggcg agcggtaaat gcgggaaagt tgtgattaac
     1201 ttcccggatt aaggagtcag cggatgacca tctatacctt atctcacggg ccgctaaagc
     1261 tggacgtttc tgaccggggc ggcgtcatcg aaggcttctg gcgtgacgcg acgccgctct
     1321 tacgtcccgg taaaaaaaac ggtgtggcaa ccgacgcctc ttgttttccg ctggtgccgt
     1381 ttgcaaaccg ggtgagcggc aatcgttttg tctggcaggg gcgtgagtat caactgcaac
     1441 cgaatgttga gtgggatgcg cactatctgc acggcgacgg ctggctgggg cagtggcaat
     1501 gtgtctcgcg cagcgaagat agcttgtgtc tggtgtatga acatcgcagc ggtgtttatc
     1561 actatcgggt aagtcaggcg tttcatttaa cggcagatac gctgacggtg acgctctctg
     1621 tcaccaatca aggggcagag acgctgccat ttggtaccgg ctggcatcct tattttccgt
     1681 tgtcaccaca aacgcggact caggcgcagg cgagcggtta ctggctggag cgggagcagt
     1741 ggctggcggg tgagttttgc gagcagctac cgcaagagct ggatttcagc cagctcgcgc
     1801 cgttgccgca ccagtgggtg aacaatggct ttgccggatg gaatggtcag gcccgcatcg
     1861 agcagccgca ggagggttat gccatcatca tggaaacgac gccacctgca ccgtgttatt
     1921 tcatctttgt ttccgacccg gcgtttgata aaggatatgc gtttgatttc ttctgtctgg
     1981 aaccgatgag ccatgcgccg gatgaccatc atcgcccgga agggggtgat ctcattgcgc
     2041 ttgcaccagg ggaatcaaca acttcagaga tgtcgttgcg ggttgcgtta ctgtaattta
     2101 taaaatgccg gataaggcgt tcacgccgca tccggcatct ttcctaacgc cgatcgagag
     2161 aaattgcccc cggcccggta attgccaaca gcaggaatgc gccagcgata ctgacattct
     2221 tccagaaatt aatcatattt ggcccaaccg catcgccggt catatcccag taatggtgac
     2281 caattatcgc tgtacccagc gtgtagaaaa taaacagcac cgccagcgga cgggtgaaaa
     2341 agccaagcac gattaatatc gcggcgggca cttccataac taccgcaata atcgctgcca
     2401 gcattggcat tggcgcgccc agcgaggcca tatattggac cgtaccgtca aagcccatca
     2461 ttttgggaaa accaaaaata atgaaaatta agatgacggc gatacgggca attaataaca
     2521 aaacggggcg ggcagcacca aaatcaaaat aacgtagtga gttcataacc aatccctttg
     2581 caagataatg tgatttaaac gtaatacaca ctcttgcacc tcgccacgcc ccaggcgttg
     2641 agatattcgc taattatcct ggttacagtg atttaagcgc gatgttctca tctgtcagcc
     2701 gtttcgcatc aaacgtttta ccgctctgga tccatttgcg gattgggcga atctcacgtc
     2761 cctgattcag cgttaccgca ccgataagca cgccgttttg cagattaaac caaatcgcct
     2821 tctgagtttc cgggttgcca cgacaaagcc agtcatcgcc acgcatatcg ccaataaact
     2881 gtaagttatc actgtactga tcgctccaga accacggcgg cggcagtcgc ggaagcggta
     2941 gccccaacat tgcggaagcg gcaatttgcg cctggttatt ggcgttttcc caactttcgc
     3001 agcggtgtag tgcgccatta tcaagacgga tgattgccac atcgccaccg gcaaagatcg
     3061 cgggatcgca ggtgcggcaa gcttcatcaa tgacaatacc attggcagta tcaaggttgg
     3121 cctcgcgagc cagttggtcg ttggcgctga taccaatacc gtaaatcacc acatcggccc
     3181 gaagcgtttc gccactttgc agcgtcagtt ctactttttc accatcgacc acatgttcaa
     3241 tggcattatt gagcagaatg cgcacaccag cctgctgatg gcgcggtaaa agatagcgtt
     3301 gcacgggcgg tggtgcatta cggcccatga cgcttgccgc cagttcaatc actgtcacct
     3361 tacatccacg ctgcgtggcg ctggcagcca gttccagacc aatagttccg gcaccgacaa
     3421 tcacgactga ccgttcgggc tgcagaactt ctcgcagtct ggcggcatca ccggcatggc
     3481 gcagggtaaa gcagcgttct cccagtgcat caagcaacgg cagcggtcga gctgccgcgc
     3541 cggttgctat aaaaagctga tcccagtgcc agctttcgcc gttagctaac actaactctt
     3601 gtgtgtcgcg gcccaatgtt ttgatggtta caccggaatg cagatgaaca ttgttttcct
     3661 gccaccagtg agcgggtaac acagactgca actgtgggga atcttccagc aacatggatt
     3721 tcgagagcgg ggggcgttca taaggaagat gttgctcatc ggaaaacaga tgcagctcac
     3781 cgctgaaccc ttgctggcgt agcaaggccg cagccattgc cgccgcttgc ccgccaccga
     3841 caataatgat cgttttttct ttcatcgtgc ttccttaaag atccagccca gccgctacgt
     3901 ggcgaatgcc gcgaatcgct aaacccgcat cagcgttgat catcacaccg cttaatgcgc
     3961 gattattgcg ccgcgatgcc aacatcacat acggacccgt aaaatccgcc ggttgcggga
     4021 aaaattgcag cggtaaaatg gcggcaattt tctccggcgt cagagactgc attatcgagg
     4081 tttcactttg cctgagcgcc tgtgggccgc gcaggtcgct ggccatacca cacgggccga
     4141 cgccattcac ccgcactttc ggtgccagtt cataagccag ttggcgaata agtccggttg
     4201 cggcatgttt actggcggtg tacagcgggc ctccgccgcc gggataccag gcggcatttg
     4261 acagtgtgaa aatcatgctg ccttcactgg cgattaacgc cggagcgcag gcttttgcgc
     4321 ccagcaggta accgagtacg ttgacgttaa acagctcgtg gaagccagtt tcgagcgtct
     4381 ctgcgggagt attaaccagt gaggcattgt gatcccagat gcccgcattg ccgataaaac
     4441 aatccagctt gccagaacga gtcaggatct gattaaccgc gcgttgataa tcggcataac
     4501 aggtcacgtt accttccacc gccagaatat gttcgccaaa tcgctgacgc agactggcga
     4561 ctttagccgc cgacagttcc agcgtggcaa cctgcgcgcc ttcttcgata aatcgctcga
     4621 ccagcgccag ccctaatccc gatccgccgc cggtaataaa gatggactcg ttatgcagat
     4681 cgctcatggc tgcgcctccg gtaagtcgat gaagatgtca ccaccatcaa cgtgtactgg
     4741 ataagtggtg agcggatcgg tggcgggcag gcataacgct ttccccgttt tcaggcaaaa
     4801 actggcggcg tgcagcgggc actccaccgt ggcgtcatct tccagatacc cttctgacat
     4861 cgacgcatta ccatggctgc aacgatcgtt aatggcataa aactcgccgc ctacgttgaa
     4921 cagggcgatg acgggcgagg tatcgatccg gagagcctca ccctccggca catccgcaac
     4981 gggacacgca taaattcgat tcatcagaac agtacactca ggttatggga ggagatgacc
     5041 gcttgatcca ggacgatatc ccgttccagc aagcgccagt tcccgtcctc cagacggcga
     5101 actttgtcga aacgcgttcc aacatagaat gtttcatcgc gctctttttg tgcccgataa
     5161 agcagataat tcaccctcac ggcaaatacg tttgggatgt cggtttcgct tacctggcag
     5221 ttgctgatta agtgacgagt gcgtgacggc ggttcttctg cccaggccat gccggtttcc
     5281 agacgggcga ttcgccgttc cagctggtct ttggtgtcat taaaaatcca ggttgtcggc
     5341 ggttgaacgc ctttgcggcg gtcgcgcgtt tgtgcgttaa ccgtggtgcg catggtgtaa
     5401 cgaatctctt cgtcgagctg tgccagccag tctcgaaatc tccagtcatc cagcagactg
     5461 gcttcgtgaa agagaaactg gctaatgcgg tgatgtaact ccagtgaaac ttgcgcactc
     5521 atttcatcac ctcctgctgg taagcggcgg ttttatcgag cacttcctgc cagctttcgc
     5581 tactcaggag atcggcccag cgttggtaca ttccacgagc ggccgtttct gagaagatat
     5641 agttagtaat gcctggaatg ccgtcgtcgc gacgcttttc ctgaccaagc cccatttcca
     5701 gacacagttt gctgttgcgg gcgcggtgac ctttcagcaa tttctggatt tcacaccagt
     5761 tctccgagtc atcctgctcg agaaaaccag caggaccaaa agcacgagtg gcgctgtttt
     5821 caaaagcggc tttaacttca tcggaggcgg ctttgtcagt aatacagaac gcccacactt
     5881 caacttgatc agggccgcgc ggatgccaga cgcggagtgt ggcagtgccg tttagccatg
     5941 aaagcgtggg gaatatattg ttatgacccg ccagacgcag ggcgcgaact tcacctaaac
     6001 gttgttctgc ttcggcatag gtttcgcggt aatagctgga aaccgcgcca tcgacccaga
     6061 cattagcatc cggtttttca gtaaagaaga aaccgctgcc gtgaccgtcc tgaccaaact
     6121 gcagcgcatc tttggcggtt tcccacaccg ggcgggcagt ttgtccatca ccgaggcgct
     6181 tatcgctgcc atcatctttc gcccctaata cctgaacggc agaagcatgg ctgaacagag
     6241 catgatactg gtcactggcg aactgctctg ccgggaattt ccagttgcag ttgatcaccc
     6301 acttttgtac gccgccgaca atttcggtgc cgccttcgcg acgatccagc atgccatcca
     6361 gataccaggc aatgtcacca aggtaatcac gcaggcccgg tgcgctggta tcccagttgc
     6421 caaaaatcag ccctttataa ctctccacac aaggaacttc gtttagtccc cagtgggatt
     6481 tacacaaccc ttgtgggtag gcgcgaggtt ccagcggtac atcgatcaac tcgccgttaa
     6541 tgccataaga ccagccgtga tacggacagg taaaggcgcg agtgttgccg caatctgcat
     6601 aactcacacg catggcccgg tggcggcatt ggttgagaaa cgccttaatg ctgccgtctt
     6661 tctggcgcac cacgacaacc gcatcttctc ccatgtaggt gttaaagaaa tcaccgggtt
     6721 ttgggatctg gctttcgtgg gcgagaaata gccagcaacg accgaaaatg cgctcaagct
     6781 ccagttggta aatgtccggg tcggtataaa tacgcggagt gacccgaccg ttttgggtgt
     6841 caatcagttg gtaaatgttc aaatctgagg gtgtggtcat attttttaat cctgaaagat
     6901 aagatgtatt gaccttctat ttttgtgcca taaggatgtt gctggttggt tgctaatatg
     6961 tgaaatagtt aatttctacc agctgagacg ttttttcgat aacaagggga aggtgatgga
     7021 actacggcat ttacgctatt tcgtcgcagt ggcgcaggca ctgaacttta cccgtgcggc
     7081 ggaaaaactg catacctcac agccttcgtt aagcagccag atccgcgatc ttgaaaactg
     7141 tgtcggtgtt ccgttactgg tgagggataa gcgcaaagtc gcgttgacgg cggcgggaga
     7201 atgttttctc caggacgcgc tggcaatcct cgaacaagcg gaaaatgcca aattacgggc
     7261 gcggaaaatt gttcaggaag acagacaatt aaccattggc tttgtgccat cggcggaagt
     7321 gaatttactg ccaaaagtat taccgatgtt tcgtctcaga cagccagata ccttaattga
     7381 gctggtgagt ttaatcacca cggaacagga agaaaaaatt cgccgtggtg aactcgacgt
     7441 cggcttaatg cgccatcctg tttatagccc ggagattgat tatctggagc tttttgacga
     7501 accattagtg gtggtgttac cggttgatca ccctttagca catgaaaaag agatcactgc
     7561 cgcgcaactg gatggcgtta atttcgtcag tactgatcca gcgtattccg gttcgcttgc
     7621 gccgatcgtt aaagcgtggt ttgcgcaaga aaacagccag ccaaatatcg tccaggtggc
     7681 aacgaatatt ctggtgacca tgaatctggt ggggatgggg ctgggcgtca ctttgatacc
     7741 cggttatatg aataatttta ataccggcca ggtggtattt cgacccattg ccggaaatgt
     7801 gccttccatt gctttactga tggcgtggaa gaaaggggag atgaagccgg cattacgcga
     7861 tttcatcgcc attgtgcagg aacgtttggc aagcgtaacg gcataattac gcattatttt
     7921 tgcaacatgc gtcgcggatc gcagtttttt agtgcttgtg aactggtgtt acagacatcg
     7981 ggaagcaggc tcgaatattc ttatttttca acttgcacca acattcgatt aaccccagac
     8041 taacgcctcc tgacgggagg gactcatggt tttgcaatcc acgcgctggt tggcgctcgg
     8101 ctatttcaca tactttttta gttacggcat ttttctacct ttctggagcg tctggcttaa
     8161 ggggattggt ttaacgccag aaaccatcgg cctgttattg ggggcaggtc tgattgcccg
     8221 ttttctcggg agtttgctca tcgcgccccg cgtcagcgat ccttctcgcc tgatttccgc
     8281 cttgcgcgtg ctggcactgc tgacacttct ctttgctgtc gcattctggg cgggggcgca
     8341 cgtagcgtgg ctgatgctgg tgatgattgg ctttaacctc tttttctcac cgctggtacc
     8401 gttgaccgat gcactggcga atacgtggca aaagcagttc ccgcttgatt acggcaaagt
     8461 gcgactgtgg ggctcggtgg cgtttgtcat tggctcggcg ctgacgggca aactggtcac
     8521 tatgtttgat tatcgggtga tcctcgcgct gttgacgttg ggcgtggcat ccatgctgct
     8581 cggctttctc atccgtccga cgattcagcc acaaggggca agccgccagc aggagagcgc
     8641 cggttggtca gcgtggttgg cgctggttcg ccagaactgg cgctttctgg cctgcgtttg
     8701 tttattgcag ggggcgcatg cggcctatta cggttttagc gccatttact ggcaggcagc
     8761 tggctactcg gcctcggcgg tgggctattt gtggtcgctg ggcgtggtgg cggaagtcat
     8821 tatctttgcg ctgagtaata aacttttccg ccgttgtagt gcacgcgata tgctgttgat
     8881 ctcggcgatt tgcggcgtag tgcgctgggg cattatggga gcaacgacgg cgatgccgtg
     8941 gttgatagtg gtgcaaattc tgcattgcgg caccttcacg gtctgccacc tggccgccat
     9001 gcgctatatt gccgctcgcc agggtagcga agtcatccgt ttacaggcgg tttactctgc
     9061 cgtcgcgatg ggcggcagta tcgcgatcat gaccgttttc gccggtttcc tgtatcaata
     9121 tctggggcac ggcgtgttct gggtgatggc gctggtggcg cttccggcaa tgtttttgcg
     9181 cccgaaagtt gttccctcat gctgattcga gcattttgcg gatttgctcc tgttgatgtg
     9241 ttgtcagcgt caggtccgta tagatcagcg gtggtgaaaa gagcggtaac ggcatggtat
     9301 aaggagcaat aatcagtgcc gcgccgcgcg gagcgcctgt ctgcaaaaat acctttaccg
     9361 acatatgttt aatgttgagc ggcagtaacg ttagttcgcg tagctgctgc tcaatctgcg
     9421 cttctcgctc gctatcattc ccggtcagta gaataatctg tttctcatgc aggtcgtttt
     9481 cctgcattag ccaggcacca aaaatcaccg cgaccagacc gctttcctca tcagaaagat
     9541 ggacgccgta ttcactttca aatccggcca gcgccgcgcg ggtggtgcgc accaggcgtg
     9601 ggtacaggcg ggcgaactct tccggcaggg tgttatcaat accgatggca aacaaactgc
     9661 gatttaacgc ctgggcgagg tgggtataaa gctgatcgca taacccctgt tcatcataaa
     9721 aacgaacatt tcccagctca cgaaaatggt ttaccagacg tttgatagac tgacgcagtt
     9781 gtctgtcccg ctgatgcgca tcccgcagtg gatcgggaac ccgcaacatg gaaaaaagta
     9841 atgccataaa cagtggctca tcaggcggta caggctggag cgcccgacgc tgccagtggc
     9901 gtccaatttc ctgcgctacc tgaaattcaa ggcaggattc cgcccagcga cgttggagcg
     9961 gattaaactg aggcgtaatt ccagcgtggt gttgcagcaa acaatattgc agatacagac
    10021 acaggaaatg aatatcgcgc gtttcaaagc gtttttgcag ccgtcgggag cagagattca
    10081 ctaacgcttg tagattggta tcgtcgtaaa agttacgcgc aattccgcgc cgcttcagtt
    10141 cactcttcag ggcgggggtg aaatggctgg taataaatga cggacagaga cggaaaccac
    10201 gtcgtagcca gtgaaataaa cacaaacgtt ggttaagcac tgtaccttca acccggtagc
    10261 taccgtcata accagtagtc agtgtgagtt gatgatagcg caggatctcc cgtcctgttt
    10321 cgctgatatc aagactggca atatcatcat ccacaccatt aagctcgctg aaagttgccg
    10381 tggtggcggt caaccccggc tgaaagagtg tcagcaagat ctggcagcgg cgctggggag
    10441 ccgaaaggac agatggtgga gcaagcgtag gcatcatctg tagatctccc ataagcataa
    10501 ttgataagaa tagctaaagt ttgctcaggg aaatggcgaa gggaatgcta atcatcagaa
    10561 atgttggcaa gcgtcacaga atttttctca tcttaaactg ttctggccag tggattagca
    10621 tgtcttaagg tggttttgtg aatgattatc gtgctagcga tcatgggtta gttctgcgga
    10681 ttcaacgcgc taaggataaa atccaccatc tgttcgcgat aaacatcgcc gtgacgatcg
    10741 gaaaaagcat caatgtgttc gccatccggg attaggatca accgttttgg ctcttttgcc
    10801 aggctataca acttttcgct gtgctgccat gggataacgt gatcagcttt accgtgaatc
    10861 agtaaaagcg ggatcgggct gacgctggcg atgtaatttt cgccgctgta actctcatca
    10921 agtaagtagc cactgccggg gatcatctgg ttggcgatgg tcgcataaga ggcaaatgtg
    10981 gagtcgagga tcaccgcacg tatgccttca cgatcaccct gaccaataac atccagaata
    11041 ttcgccccgc caatactctg cccgaacagc accagccgtt gtgggtttac atcactgcga
    11101 tggcgcacca cattgatggc actttgcgta tcgtccagca atccggcctg ggacggcgtg
    11161 ccttttgatt taccaaaccc gcgataatca aacataaaaa cgttgaaatt acgctcgggt
    11221 aaccaactga ccagcggcca gtgggcggac atatttccgg cattgctgtg agcatgaata
    11281 atggtggcaa tggcattttc agcggggcca gttgcagaag ggataaacca accatgtagg
    11341 cgagtgccat ctttagcggt gaattctact gattcggctg accagggatc ggggccgtag
    11401 attttgtcgt cagggtaata gaaaaaattg atggcgatgc gcggtattaa ataaatgcag
    11461 aaggcaacaa caaagagaat aaacagaatt ttgagaacgc gtttgttcac tggcagcgcc
    11521 ataacctttc cttgcgactt ctttatcatc cattaatcgg ggaaagatgg tgggagagtg
    11581 gcgaaagaaa gtaaagcggt gaggaagtat ttcggaatag cgcctgaaag gcgagggcgg
    11641 gtgagtgaca tcacccgcca gagtcattaa cgcttcaggg cgtcgcttaa ctcgtcacgc
    11701 atgttcgcca gcatggcttt aacaacgcgc gggttaccag caacgatgtt accggtcagc
    11761 atgtagttat gaccaccggt gaagtcgctg acgatgccgc ccgcttcacg aaccagcagc
    11821 tcgcctgccg cgaaatccca cggacgcaga ccgatttcaa agaaaccgtc aacgcgaccc
    11881 gcagcaacgt aagccagatc cagcgccgca gaaccggtac gacggaagtc tgcacattcg
    11941 ttgaacagtt tgccgacgat gttgatgtag gtggtggcgt actgttttgc tttgaacggg
    12001 aagccggtcg ccagaatagt accgtcgaga tcgcgagcgg tgctgccgcg cagacggtag
    12061 ccgttcagct gtgcgccctg accgcgagtg gcggtgaaca gttcgttacg cataggatcg
    12121 taaaccacag caacttcagt gcggcctttg atacgaacgg cgatagatac cgcgaagtgc
    12181 ggcagacgtt tgataaagtt ggtagtgcca tccagtggat cgataaccca ttgaacatcc
    12241 tgatcagtac cttcaagttc accgctttct tcggtgatga tggtgtgctg tgggtaagat
    12301 ttacgaatcg tgtcgataat caccgcttcg gcagctttat ctacgttggt cacgaagtcg
    12361 ttactgcctt tctggctcgc ttctacagcg tccggggttt catagttttt ggcaattaaa
    12421 ttacccgcct tgcgcgctgc gcgcacggcg atgttcagca tcggatgcat cggtctctct
    12481 cactggatgt taaagaacgg gaaaacggcg cagagtatag cagcgagatc ggcatctgtc
    12541 ttcgttttat gataagatgc gcgaataatc tttagacgaa gaaagacaat gctgcaaaat
    12601 attcgaattg tgctggtgga gacgtcacac accggcaata tgggttctgt tgcccgtgcc
    12661 atgaaaacaa tgggattaac caatctgtgg ttggttaatc cactggtgaa acctgactcc
    12721 caggcgattg ccctggcagc aggggccagc gatgtgattg gtaatgctca tatcgtcgat
    12781 acgctcgacg aagcgttagc cggttgtagc ctggtggtgg gcaccagcgc acgctcccgc
    12841 acgctgccgt ggccgatgct cgacccgcgc gaatgcggtc tgaaaagcgt cgctgaagcg
    12901 gcaaataccc cggtggcgct ggtttttggt cgcgaacgcg tcggcttgac caatgaagag
    12961 ttacagaaat gccattatca tgtcgcgatt gccgctaacc cggaatacag ttcgctgaac
    13021 ctggcaatgg cggttcaggt tattgcctat gaagtgcgca tggcctggct tgcaactcag
    13081 gaaaatggtg agcaggtcga gcatgaagag acgccgtatc cgctggtcga tgatctggag
    13141 cgtttttatg gtcatctgga acaaacgctg ctggcaaccg gttttatccg tgaaaaccat
    13201 ccggggcagg tgatgaataa attgcgtcgt ttgtttaccc gtgcgcgccc ggaaagccag
    13261 gaattgaata tcctgcgcgg gattctggct tctatagagc agcagaataa aggtaataag
    13321 gccgaataat agtggttgcc tgatgcgacg cttaacgcgt cttatcaggc ctacaatgta
    13381 cagaaccgta ggtcggataa ggtgttcaca ccgcatccga caacaggtac aaacgccacg
    13441 ataaaaaaat ggcactgaag gttaaatacc cgactaaatc agtcaagtaa atagttgacc
    13501 aatttactcg ggaatgtcag acttgaccct gctatgcaat acccccactt ttacaataaa
    13561 aaaccccggg caggggcgag tttgaggtga agtaagacat gagactgaca tctaaagggc
    13621 gctatgccgt gaccgcaatg cttgacgttg cgctcaactc tgaagcgggc ccggtaccgt
    13681 tggctgatat ttccgaacgt cagggaattt ccctttctta tctggaacaa ctgttttccc
    13741 gtctgcgtaa aaatggtctg gtttccagcg tacgtggacc aggcggtggt tatctgttag
    13801 gcaaagatgc cagcagtatc gccgttggcg aagtgattag cgccgttgac gaatctgtag
    13861 atgccacccg ttgtcagggt aaaggcggct gccagggcgg cgataaatgc ctgacccacg
    13921 cgctgtggcg tgatttgagc gaccgtctca ccggttttct caacaacatt actttaggcg
    13981 aactggttaa taaccaggaa gtgctggatg tgtctggtcg tcagcatact cacgacgcgc
    14041 cacgcacccg cacacaagac gcgatcgacg ttaagttacg cgcttaataa aaagtattca
    14101 gaatcaggcc ggagtgttta acactccgta aacacggtcg tacatccagc cggtagcctg
    14161 gttccttgca ttgagtgatg tacggagttt atagagcaat gaaattaccg atttatctcg
    14221 actactccgc aaccacgccg gtggacccgc gtgttgccga gaaaatgatg cagtttatga
    14281 cgatggacgg aacctttggt aacccggcct cccgttctca ccgtttcggc tggcaggctg
    14341 aagaagcggt agatatcgcc cgtaatcaga ttgccgatct ggtcggcgct gacccgcgtg
    14401 aaatcgtctt tacctctggt gcaaccgaat ctgacaacct ggcgatcaaa ggtgcagcca
    14461 acttttatca gaaaaaaggc aagcacatca tcaccagcaa aaccgaacac aaagcggtac
    14521 tggatacctg ccgtcagctg gagcgcgaag gtttcgaagt cacctacctg gcaccgcagc
    14581 gtaatggcat tatcgacctg aaagaactgg aagcagcgat gcgtgacgac accatcctcg
    14641 tttccataat gcacgtaaat aacgaaatcg gcgtggtgca ggatatcgcg gctatcggcg
    14701 aaatgtgccg tgctcgaggc attatctatc acgttgatgc aacccagagc gtgggcaaac
    14761 tgcctatcga cctgagccag ttgaaagttg acctgatgtc attctccggt cacaaaatct
    14821 atggcccgaa aggtatcggt gcgctgtatg tgcgtcgtaa accgcgcgta cgcatcgaag
    14881 cgcaaatgca tggcggcggt cacgagcgcg gtatgcgttc cggcactctg cctgttcacc
    14941 agatcgttgg tatgggcgaa gcctatcgca tcgcaaaaga agagatggcg accgagatgg
    15001 aacgtctgcg cggcctgcgt aaccgtctgt ggaacggcat caaagatatc gaagaagttt
    15061 acctgaacgg tgacctggaa cacggtgcgc cgaacattct caacgtcagc ttcaactacg
    15121 ttgaaggtga gtcgctgatt atggcgctga aagacctcgc ggtttcttca ggttccgcct
    15181 gtacgtcagc aagcctcgaa ccgtcctacg tgctgcgcgc gctggggctg aacgacgagc
    15241 tggcacatag ctctatccgt ttctctttag gtcgttttac tactgaagaa gagatcgact
    15301 acaccatcga gttagttcgt aaatccatcg gtcgtctgcg tgacctttct ccgctgtggg
    15361 aaatgtacaa gcagggcgtg gatctgaaca gcatcgaatg ggcacatcat taatcggtat
    15421 cggaatcagg agaatttata atggcttaca gcgaaaaagt tatcgaccat tacgagaatc
    15481 cgcgtaacgt gggttccttt gacaacaacg acgagaacgt cggcagcggc atggtgggtg
    15541 caccggcctg tggcgacgta atgaagttgc agattaaagt caacgatgaa ggtatcattg
    15601 aagacgcgcg ttttaaaact tacggctgcg gttctgctat cgcttccagc tccctggtca
    15661 ccgaatgggt gaaagggaag tctctcgacg aagcgcaggc gatcaaaaac accgatattg
    15721 ctgaagaact tgaactgccg ccggtgaaaa ttcactgttc tattctggca gaagacgcga
    15781 tcaaagccgc cattgcggac tataaaagca aacgtgaagc aaaataagag ttgaggtttg
    15841 gttatgtcga ttacactgag cgacagtgca gcagcgcgag taaatacctt tctggctaac
    15901 cgcggcaaag ggtttggcct gcgtctgggc gtgagaacct ccggatgttc aggtatggct
    15961 tatgtactgg aatttgttga cgaaccgacg ccggaagaca tcgtgtttga agacaaaggc
    16021 gtgaaagtcg tggtcgatgg caaaagcctg caatttctgg acggtacgca gctggacttc
    16081 gtaaaagaag gcctgaacga agggtttaaa ttcaccaacc cgaacgtcaa agatgagtgt
    16141 ggttgcggcg aaagcttcca cgtttgatgc gcataccgat aaccccaccg tggtcgcctg
    16201 cgcgtggggt ttgttttacc tgattcgccg ttatcgcggc ggatcgcagc cctgagaatg
    16261 ttatggatta cttcaccctc tttggcttgc ctgcctgtta tcaactcgat acccaggcgc
    16321 tgagcctgcg ttttcaggat ctacaacgtc agtatcatcc tgataaattc gccagcggaa
    16381 gccaggcgga acaactcgcc gccgtacagc aatctgcaac cattaaccag gcctggcaaa
    16441 cgctgcgtca tccgttaatg cgcgcggaat atttgctttc tttgcacggt tttgatctcg
    16501 ccagcgagca gcatactgtg cgcgacaccg cgttcctgat ggaacagctg gagctgcgcg
    16561 aagaactgga cgagatcgaa caggcgaaag atgaagcgcg gctggaaagc tttatcaaac
    16621 gtgtgaaaaa gatgtttgat acccgccatc agttgatggt tgaacagtta gacaacgaga
    16681 cgtgggacgc ggcggcggat accgtgcgta agctgcgttt tctcgataaa ctgcgaagca
    16741 gtgccgaaca actcgaagaa aaactgctcg atttttaatt tctggaagct aaacatggcc
    16801 ttattacaaa ttagtgaacc tggtttgagt gctgcgccgc atcagcgtcg tctggcggcc
    16861 ggtatcgacc tgggcacaac caactcgctg gtggcgacag tgcgcagcgg tcaggccgaa
    16921 acgttagccg accatgaagg ccgtcacctg ctgccgtctg ttgttcacta tcaacagcaa
    16981 gggcattcgg tgggttatga cgcgcgtact aacgcagcgc ttgacaccgc caacaccatt
    17041 agttctgtta aacgcctgat ggggcgctcg ctggctgata tccagcaacg ctatccgcat
    17101 ctgccttatc aattccaggc cagcgaaaac ggcctgccga tgattgaaac ggcggcgggg
    17161 ctgctgaacc cggtgcgcgt ttctgcggac atcctcaaag cactggcggc gcgggcaact
    17221 gaagccctgg caggcgagct ggatggtgtc gttatcaccg ttccggcgta ctttgacgat
    17281 gcccagcgtc agggcaccaa agacgcggcg cgtctggcgg gccttcacgt cctgcgctta
    17341 cttaacgaac cgaccgctgc ggctatcgcc tacgggctgg attccggtca ggaaggcgtg
    17401 atcgccgttt atgacctcgg cggcgggacg tttgatattt ccattctgcg cttaagtcgc
    17461 ggcgtgtttg aagtgctggc gaccggcggt gattccgcgc tcggcggcga tgatttcgac
    17521 catctgctgg cggattatat tcgcgagcag gcgggcattc ctgatcgtag cgataaccgc
    17581 gttcagcgtg aactgctgga tgccgccatt gcagccaaaa tcgcgctgag cgatgcggac
    17641 tccgtgaccg ttaacgttgc gggctggcag ggcgaaatca gccgtgaaca attcaatgaa
    17701 ctgatcgcgc cactggtaaa acgaacctta ctggcttgtc gtcgcgcgct gaaagacgcg
    17761 ggtgtagaag ctgatgaagt gctggaagtg gtgatggttg gcggttctac ccgcgtgccg
    17821 ctggtgcgtg aacgggtggg cgaatttttc ggtcgtccac cgctgacttc tatcgacccg
    17881 gataaagtcg tcgctattgg cgcggcgatt caggcggata ttctggtggg taacaagccg
    17941 gacagcgaaa tgctgttgct ggatgtgatc ccgctgtcgc tgggcctcga gaccatgggc
    18001 ggcctggtgg agaaagtgat cccgcgtaat accacgattc cggtggcccg cgcccaggat
    18061 ttcaccacct ttaaagatgg tcagacggca atgtctatcc atgtgatgca gggtgaacgt
    18121 gaactggtgc aggactgccg ctcgctggcg cgttttgcac tgcgtggtat cccggcgcta
    18181 ccggctggcg gcgcgcatat tcgcgtaacg ttccaggtcg atgccgacgg tcttttgagc
    18241 gtgacggcga tggagaaatc caccggcgtt gaggcgtcta ttcaggtcaa accgtcttac
    18301 ggtctgaccg atagcgaaat cgcttcgatg atcaaagact caatgagcta tgccgagcag
    18361 gacgtaaaag cccgtatgtt ggcagaacaa aaagtagaag cggcgcgtgt gctggaaagt
    18421 ctgcacggcg cgctggctgc tgatgccgcg ctgttaagca ccgcagagcg tcaggtcatt
    18481 gacgatgctg ccgctcacct gagtgaagtg gcgcagggcg atgatgttga cgctatcgaa
    18541 caagcgatta aaaacgtaga caaacaaacc caggatttcg ccgctcgccg catggaccag
    18601 tcggttcgtc gtgcgctgaa aggccattcc gtggacgagg tttaatatgc caaagattgt
    18661 tattttgcct catcaggatc tctgccctga tggcgctgtt ctggaagcga atagtggtga
    18721 aaccattctc gacgttgcgc tgcgtaacgg tatcgagatt gaacacgcct gtgaaaaatc
    18781 ctgtgcttgc accacctgcc actgcatcgt tcgcgaaggt tttgactcgc tgccggaaag
    18841 ctcagagcag gaagacgaca tgctggacaa agcctgggga ctggagccgg aaagccgttt
    18901 aagctgccag gcgcgcgtta ccgacgaaga tttagtggtc gaaatcccgc gttacactat
    18961 caaccatgcg cgtgagcatt aacagaggtt agtatgggac ttaagtggac cgatagccgc
    19021 gaaattggcg aagcactgta cgatgcgtat cccgatcttg atccgaaaac ggttcgattc
    19081 accgatatgc atcagtggat ttgcgatctg gaagatttcg acgacgaccc gcaggcatcc
    19141 aacgagaaaa tcctcgaagc gattttgtta gtctggctgg acgaagccga ataaatgaac
    19201 gggctgcctg ggggtagccc gttttgctgt taaacgaata aggataacta aaatgacaga
    19261 agagatgaaa attaccctct ctacccaacc tgccgacgcg cgctggggag aaaaagcgac
    19321 ttacagcatt aataatgatg gcattaccct gcatttgaac ggggcagacg atctggggct
    19381 gatccagcgt gcggcgcgca agattgacgg tctgggcatc aaacatgttc agttaagcgg
    19441 tgaaggctgg gatgcggatc gctgctggac attctggcaa ggttacaaag ccccgaaagg
    19501 cacgcgtaaa gtggagtggc cggatctgga cgatgcccag cggcaggaac tggataaccg
    19561 cctgatgatc atcgactggg tgcgtgacac catcaacgca ccggcagaag aattgggacc
    19621 atcgcaactg gcacagcgtg ctgttgatct gatcagcaac gtcgcgggcg atcgtgtgac
    19681 ttatcggatc accaaaggtg aagatctgcg tgatcaaggt tatatggggc tgcacacggt
    19741 cgggcgcggt tcagaacgtt ccccggtatt gctggcgctg gattacaacc caacaggcga
    19801 taaagaagcg ccagtgtacg cgtgcctggt aggtaaaggt atcacttttg actccggcgg
    19861 ctacagcatc aaacagactg cgtttatgga ctcgatgaag tcggacatgg gcggcgcggc
    19921 aacggttacc ggggcgctgg catttgccat tacgcgcgga ctgaacaagc gcgtgaagct
    19981 gttcctctgc tgtgcggata acctgatcag cggcaacgcg ttcaaactgg gcgatattat
    20041 tacctatcgc aacggtaaaa aagttgaagt gatgaacact gatgccgaag ggcgtttggt
    20101 gctggccgat ggcctgattg atgccagtgc gcagaaaccg gaactgatca ttgatgcggc
    20161 gaccctcacc ggggcggcga aaactgcgct gggtaatgat tatcacgcgc tgttcagttt
    20221 tgacgatgcg cttgccggtc gcttgctggc gagtgccgcg caggagaatg aaccgttctg
    20281 gcgtctgccg ctggcggagt tccaccgcag ccagctgccg tctaactttg cggaactgaa
    20341 caataccgga agcgcggcgt atccggcagg cgcgagcacg gcggcgggct tcctgtcgca
    20401 ctttgttgag aactatcagc aaggctggct gcatatcgac tgctcggcga cttaccgtaa
    20461 atcgccggtt gaacagtggt ctgcgggcgc gaccgggcta ggtgtgcgca cgattgctaa
    20521 tctgttaacg gcgtaaacgt cttatttggc ctacaaaatt gcgaaaatcc aatagattga
    20581 gattcccttg taggcctgat aagcgtagcg catcaggcac ttgtgccccg aacgttgaat
    20641 gaattgtggt tcttatgtcc gaaacaaaaa acgaacttga agatctgctg gaaaaagcag
    20701 caaccgaacc ggcgcaccgc ccggcctttt tccgtacgct actggaatcc accgtctggg
    20761 tgcctggtac ggcggcgcag ggcgaggctg tggttgaaga tagcgcgctt gatttacagc
    20821 actgggaaaa agaagacggc accagcgtca ttcctttttt cacctcgtta gaagcacttc
    20881 aacaggcggt tgaagacgaa caggcatttg tcgtaatgcc cgttcgcaca ttgtttgaga
    20941 tgacccttgg cgaaacgctc ttccttaatg ccaaactgcc aaccggtaaa gaatttatgc
    21001 cgcgtgaaat cagtttgttg attggtgaag aaggaaatcc gctgagcagc caggaagtac
    21061 tggagggcgg tgaatcgctg atattatcgg aagtcgcaga gccaccagca caaatgattg
    21121 attctctcac caccttattt aaaactatta agccggtgaa gcgtgctttt atttgttcaa
    21181 ttaaagagaa cgaagaggca cagcctaatt tacttattgg cattgaagcc gatggtgata
    21241 tcgaagaaat tattcaggcg gcgggaagtg tagcgaccga tacattacct ggcgatgaac
    21301 ccatcgatat ttgtcaggtg aaaaaagggg aaaaaggaat tagccacttt attaccgaac
    21361 atattgtgcc attctatgaa cgtcgctggg gtggtttttt gcgtgacttt aaacagaacc
    21421 ggataatcta aaatatgccg ccccaaaggg cggcattcgg gcttacctgc tgttctgaag
    21481 gttgttaaca accaataaat tgttgccgga gagactccgg ttattattta cctcggttaa
    21541 cagcgcacca gaaacaataa gtacgataca aaagcaccgt atcttcattg tgcggtccat
    21601 gcgaagaccg catcacgaca gcaccactgg cgatattgcc gcgatagcaa gcgctgagac
    21661 gcgcttgccc taacggtcgc ggaacatcct ttccttgagc cagcgcccgc ttgcgagacg
    21721 gcggaaaggt ccgcagtgga taatacacta acagaacaat aataactctc ttttacttga
    21781 caaagagaga gttactggcg agtattgtgt ccgctgagac gcgcttgcat tactacggta
    21841 atacaatctg ctggaaaggc cgcgaaccaa accagcaaca aataaccgcc tgattttggc
    21901 ggttttttgt tgtttaaaga aagtgaagtt acacgtttaa ctaatatctt ttatcagtta
    21961 gtatatttta atattaagcg ggatttgttt atatttgtct gaattcggac tgataagcta
    22021 aatgaattca aaatctatcc ttttttatct acttgacatc gttgatgcat aaagcgagta
    22081 ttgagtagac gagatacact tgcagtaata caatctgctg gaaaggccgc gaaccagacc
    22141 agcaataaaa aaccgccaaa ttcggcggtt ttttattgcc tgtaaaaagc ttattttacg
    22201 ggctcaaccg gtaaatctgc tcgtgcgccc cattcactcc atgcgccgtc gtacagtttc
    22261 acgtttggca catccagcgt cgcgagtgcc aacaaaacca cggctgccgt tacaccagag
    22321 ccgcagctga cgataatcgg tttgtcatag ctgacgccgc gaccaaaaaa tatcgcatcc
    22381 agttcatcgg tcgtttttag ttcgccttcg cgcaccagtt ctgtccacgg aacgttaaac
    22441 gcgccgggaa tatgtccgcg acgtaaacct gggcgaggtt catcaacttc tgcgttaaaa
    22501 cgtgcagccg ggcgggcatc gataatttgc gccgtatttt catggcttgc caataacaca
    22561 tcggttactt tcaccacggc ttcaggatta aacgcggcgt taaactctcc ttccggcagc
    22621 tctactgcgc cttcttcaaa tagcagatca tcacgctgcc agcctgcaag tccaccaccc
    22681 agaatcgaca ctttctctac accaaaggtg cgcagcatcc accatgctcg tggggctgag
    22741 aaaagattac cttcgtcata gacaatcagg tgcttatcct ggttaacgcc taattcacgc
    22801 atcgccacgg cgaacgtttc cgggcgcggc agcatgtgcg gaagcgggga agtgtgatca
    22861 gaaagcgctt cgatatcaaa aaacactgcg ccgggaatat gtccattcag atactcctga
    22921 gcaacgttac gatcttcctg tccaggcgac gccatgcggg catcgataat ctgaatttcc
    22981 gggtcatcaa tatgttcggc gagccagtcg gctcctacaa accatgtcgt ggacataggc
    23041 atctccattt ttgccggggt taggctaaat tgtcggatgt ttagtgaaaa gcgacaagca
    23101 aaagaggctg atttggctgt ctgagccaca attctcacta aaattcggat tgtatgggcg
    23161 tgatactgaa ttacataacg taaattctca cgcataataa ttattcgacg ttgctaacgg
    23221 gccattgtgg cagggatgaa aaatgaaaaa gttacgcgta gccgcctgca tgctaatgct
    23281 ggcgctggca gggtgcgaca acaacgataa cgcgccaaca gcggtgaaaa aagatgcgcc
    23341 ttctgaagtt actaaagcgg cctcttcaga aaacgtgagt tcagcaaaac tttccgcgcc
    23401 ggagcgacaa aaactggccc aacagagtgc cggtaaggcg ctgacattgc tggatctctc
    23461 tgaagttcaa cttgatggcg cagccacgct ggtgctgacg ttctccattc ctctcgaccc
    23521 ggatcaggat ttctcacgcg ttatccatgt cgtcgataag aaaagcggca aagtggatgg
    23581 tgcctgggag ctgtcagata atcttaaaga gttgcgttta cgccacctcg aaccgaaacg
    23641 tgatttgatc gtcactattg gcaaggaggt caaagcactc aacaacgcaa ccttcagtaa
    23701 agattacgaa aaaactataa ctacccgcga tatccaaccc agcgttggtt ttgccagccg
    23761 tggttcgttg ttacctggta aagttattga agggctgccg gtaatggcgc tcaacgttaa
    23821 caatgttgat gttaacttct tccgtgtgaa gcccgaatct ctgcctgcat tcattagcca
    23881 atgggaatac cgcaattcgc tggcgaactg gcagtctgaa aaactgctgc agatggcgga
    23941 tctggtttat accggacggt ttgatctcaa tcctgcgcgt aacacccgtg aaaaattatt
    24001 gctgccgctg ggtgatatca aaccgcttca gcaggcaggc gtgtatctgg ctgtgatgaa
    24061 tcaggctgga cgttacgatt acagtaatcc cgcgacgctg tttacgttaa gtgatatcgg
    24121 cgtttcagct caccgttatc acaatcgtct ggatatcttt acccaaagtc tggaaaacgg
    24181 cgcggcccag caaggaatag aagtctcttt attaaatgag aaagggcaga ctctgactca
    24241 ggcaaccagt gatgctcagg ggcatgtgca gctggaaaat gataaaaacg cggcattact
    24301 gctggcgcgt aaagacggtc agacaacgct actcgattta aaacttccgg cgctggactt
    24361 agcagaattt aacattgctg gcgcgccagg ctatagcaaa cagtttttca tgtttggccc
    24421 gcgcgatctt tatcgccctg gtgaaacagt catcctcaat ggtttattgc gtgatgcaga
    24481 tggaaaagca ttgcccgatc aacccatcaa gttagacgtg attaaacccg acgggcaggt
    24541 actcaggagc gtcgttagtc aaccggagaa tggcctctac cactttacct ggccactcga
    24601 tagcaatgcg gcaaccggta tgtggcatat tcgcgctaac acgggcgata accagtaccg
    24661 gatgtgggat ttccacgtcg aagattttat gccagagcgc atggcgctga atctgactgg
    24721 tgagaaaacc ccgctaacgc cgaaagatga agtgagattc tccgtggtgg ggtactacct
    24781 gtatggtgcg cctgctaatg gtaatacttt gcaagggcaa cttttcctgc gcccactgcg
    24841 tgaagctgtg tcagccttac ctggtttcga attcggcgat atagctgccg aaaatctttc
    24901 ccgcacgctg gatgaagttc agttgacgct ggatgataaa gggcgtggcg aagtttctac
    24961 agaaagccag tggaaggaaa cgcattcccc attacaggtt attttccagg gtagtttgtt
    25021 ggaatcgggc ggtcgcccgg tgacgcgccg cgctgagcag gttatctggc ctgccgatgc
    25081 attgccgggg atccgtccgc agttcgcctc gaaatcggtt tacgattatc gcactgacag
    25141 cacggtgaaa cagcccattg ttgatgaagg cagtaacgcc gcttttgaca tcgtttatag
    25201 cgatgcgcaa ggcgtaaaaa aagccgtgtc gggcttgcag gtgcgcctga ttcgcgaacg
    25261 ccgcgattac tactggaact ggtcagaaga tgaaggctgg cagtcacagt ttgatcaaaa
    25321 agatctgatt gaaaatgaac aaactctgga tctgaaagcg gacgaaaccg gcaaggtcag
    25381 tttcccggta gagtggggcg cttatcgtct ggaagtcaaa gcgccgaatg aagcggtcag
    25441 tagtgtgcgt ttctgggctg gctatagctg gcaggacaac agcgacggga gcggtgccgt
    25501 gcgacccgac cgtgtcacgc tgaaactgga taaagccagt tatcgccctg gcgataccat
    25561 taagttgcat attgctgcgc caacggcggg taaaggttat gcgatggtcg agtccagtga
    25621 agggccgctg tggtggcaag agattgatgt tccggctcaa gggctggatc tgacgattcc
    25681 ggtcgataaa acctggaatc gtcatgattt gtatttaagt acgctggtgg tacgtcctgg
    25741 cgataaatct cgctctgcga cgccaaaacg cgcagttggg gtgttgcatc tgccgcttgg
    25801 cgatgaaaac cgtcgtctcg atctggcgct ggaaaccccc accaaaatgc gccccaatca
    25861 gccattaacc gtgaaaatta aagccagcaa taaaaatggt gagatgccaa aacaggtgaa
    25921 tgtgctggtg tctgccgttg atagcggtgt gctgaatatt actgattacg ttacccccga
    25981 tccgtggcag gcgttctttg gtcagaaacg ctatggtgca gacatttacg atatttacgg
    26041 tcaggtcatt gaaggtcagg ggcgtctggc agctctgcgt tttggtggcg atggtgatga
    26101 gctgaaacgt ggtggtaaac cgccggtcaa tcacgtcaat attgtcgcgc agcaggcgct
    26161 gccggtaacg ctcaacgaac agggcgaagg ctcggttaca ctgccgattg gcgattttaa
    26221 cggtgaacta cgcgtcatgg cgcaagcctg gacggcagat gatttcggta gcaacgaaag
    26281 caaagtgata gttgccgcac cggtgattgc tgaactgaac atgccgcgct ttatggcgag
    26341 tggcgatacc tcgcgtctga cgctggatat cactaatctt accgataaac cgcaaaaact
    26401 gaacgttgcc ctgaccgcca gtggtttgct tgaactggtc agcgtttcac ccgcagccgt
    26461 tgaattagcg ccaggtgtgc gtactacgct gtttatcccg gtgcgagcat tgccgggtta
    26521 tggcgatgga gaaattcagg ccaccattag cgggttagcg ttaccgggtg aaaccgttgc
    26581 cgatcagcat aagcagtgga aaatcggcgt ccgtccggcg ttcccggcac aaacggttaa
    26641 ttacggtacg gcgttgcagc ctggtgagac atgggcgatt ccggcggatg gattgcaaaa
    26701 cttctcgcct gttacactgg aagggcaatt gttgttgagc ggcaaaccac cgctgaacat
    26761 cgcacgttat atcaaagagt taaaagcgta tccgtacggc tgtcttgagc aaaccgccag
    26821 cggcctgttc ccgtcacttt ataccaacgc agcccaactg caggcgttgg gcatcaaagg
    26881 cgacagtgat gagaagcgcc gtgcatcggt cgatatcggc atttcccgtt tgctgcaaat
    26941 gcaacgtgat aacggcggct ttgcgctgtg ggataaaaac ggtgacgaag agtactggct
    27001 gacggcttac gtgatggatt tcctggtccg cgcaggtgag cagggttaca gcgtgccgac
    27061 agacgtcatt aaccggggaa atgagcgtct gctgcgctat ttacaagatc cgggcatgat
    27121 gtcgatcccg tacgcggata atctcaaagc cagtaaattc gccgtacagt cttacgctgc
    27181 gctggtgctg gcccgtcagc aaaaagcacc actgggtgcg ctgcgtgaaa tctgggagca
    27241 tcgtgcagat gctgcgtctg gattaccgct gctgcaactt ggcgttgcgc tgaaaaccat
    27301 gggggatgcg acgcgtagtg aagaagcgat tgcgctggcg ctgaaaacgc cgcgtaatga
    27361 tgagcggaaa tggctgggtg attacggtag cccactgcgc gacaacgcgt taatgctctc
    27421 cttgctggaa gaaaataaac tgctacccga tgagcaaaac actttgctga acacgctttc
    27481 gcagcaggcg tttggtgaac gctggctatc gacgcaggaa agcaacgcgt tgttcatggc
    27541 tgcccgtacg atccaggatt taccgggtaa atggcaggcg caaacctctt tctcaactga
    27601 gccgctgaca ggcgagaaag cgcaaaacag caatctgaat agcgatcaac ttgccgcctt
    27661 gcaggtgacc aacagtggcg atcagccgtt atggctgcgt gtggatgcca gcggttatcc
    27721 gcaatccgca cctttaccgg cgaacaatgt gctgcaaatc gagcgtcata ttcttggtac
    27781 tgatggtaag agcaaatcgc tggactcgtt acgtagcggc gatctggtgc tggtctggtt
    27841 gcaggttaaa gccagtaaca gcgtgccgga tgcgttagtc gtggatctgc tgcctgcggg
    27901 tctggaactg gaaaatcaga atctggcgaa cggtagcgcc agcctggagc aaagtggtgg
    27961 cgaagtgcaa aacttactga accagatgca gcaggcgagc attaagcaca ttgagttccg
    28021 tgacgatcgc tttgtggcgg cggttgccgt tgatgaatac caaccggtaa cgctggtgta
    28081 tctggcgcgg gcggtgacgc cgggaacgta tcaggtaccg caaccgatgg tggaatcaat
    28141 gtatgttccc caatggcggg cgaccggcgc ggctgaagat ttgctgattg tcagaccgta
    28201 aatgcctcgc ttgttaacca aacgcggctg ctggataacg ctggcagctg cgccatttct
    28261 cctttttctt gcagcgtggg gagcagataa actctggcct ctaccgctgc atgaagtcaa
    28321 tcccgcacga gtggttgtgg cgcaggatgg gacgccgctc tggcgctttg ccgatgcgga
    28381 aggcatctgg cgttatccgg taacaatcga agatgtttct ccacgttacc ttgaagcgct
    28441 gatcaattat gaagatcgct ggttctggaa gcatccgggg gtgaatccat tctcggtggc
    28501 gcgcgcagca tggcaagatc tcacttcggg aagagttatt tccggtggca gcacgctcac
    28561 tatgcaggtt gctcgtctgc ttgatcctca ccccaaaaca tttggcggca aaattcgcca
    28621 gctctggcgc gcgttgcaac tggagtggca tctgtctaag cgtgaaattc tgaccttgta
    28681 tcttaaccgc gctccgtttg gcggtacgtt gcaggggatc ggtgcggcaa gttgggctta
    28741 tctcggaaaa tcgcctgcga atttaagcta ttccgaggcg gcaatgctgg cggttttgcc
    28801 gcaaactccc agccgtcttc gcccggatcg ttggccggag cgtgccgaag ccgcgcgtaa
    28861 taaagtgctc gaacggatgg ccgtgcaagg tgtgtggtcc cgtgagcagg taaaagagtc
    28921 aagggaagaa cccatctggc tggcaccccg acaaatgccg caactggcac cgctgttttc
    28981 gcgcatgatg ctcggtaaaa gcaaaagcga caaaatcgtt actacgctgg atgccggtct
    29041 tcaacgacgt ctggaagaac tggcgcaaaa ctggaaagga cgattaccac cgcgcagctc
    29101 actggcgatg atcgtggttg atcataccga tatgcgtgtt cgcggctggg tgggttcggt
    29161 tgatctcaac gatgattcac gctttggtca tgttgatatg gtcaatgcga tccgatcgcc
    29221 aggatcggtg ctcaaaccgt ttgtttatgg tctggcgctg gatgaaggct tgatccaccc
    29281 ggcatcactg ctgcaagacg ttccccggcg taccggtgat taccgacctg gcaactttga
    29341 cagcggtttt catggcccga tcagcatgag cgaggcgctg gtgcgctcgc tgaatttacc
    29401 tgctgtgcag gtgctggaag cctatgggcc gaaacggttt gcggcaaagt tacgcaatgt
    29461 tggattgccg ttatatttgc ccaacggtgc tgcaccgaat ctttcgctca ttctcggcgg
    29521 cgctggtgca aaactggggg atatggcggc ggcctatacc gcgtttgctc gccacggcaa
    29581 ggcaggcaaa ttgcgcttac agcctgacga tccgctgctt gaacggcctt taatgtcgtc
    29641 gggggcggcg tggatcattc gccggattat ggctgatgaa gcgcaaccct tgccggatgg
    29701 tgccttgccg cgcgtcgccc cactggcatg gaaaacgggc accagctatg gctatcgtga
    29761 tgcctgggcg attggggtta acgctcgcta tgttattggg atctggactg gcagaccgga
    29821 cggcacgccc gttgttggtc agtttggctt tgccagcgcc gtaccattgt tgaatcaggt
    29881 taataatatc ttactgtcgc gcagtgcgaa tctgccggaa gacccacgtc ctgactctgt
    29941 aagtcgtggc gttatctgct ggccgggcgg acagtctttg ccggaaggtg acggtaactg
    30001 ccgcctccgc ctggcaacct ggctgctgga cgggagtcag ccgccaactc tattactgcc
    30061 ggagcaggaa ggcattaatg gcattcgttt ccccatctgg ctggatgaaa acggcaaacg
    30121 tgttgccgct gattgccctc aggcgcgaca agaaatgata aatgtctggc cgctaccgct
    30181 ggaaccctgg ttgcccgcat cagaacaccg cgctgtgcgc ttaccaccgg cctcgacaat
    30241 ttgcccgcca tacggtcacg atgcacaact cccactacag ctgacaggtg ttcgcgatgg
    30301 cgcgattatt aaacgtttac cgggcgcagc ggaagcgact ttgccgttgc aatcaagtgg
    30361 aggggctggt gaacgctggt ggtttctaaa cggcgaaccg ttaactgaac gcgggcgcaa
    30421 cgtgaccctg catttgacgg ataaaggcga ttatcaattg ctggtgatgg atgacgtggg
    30481 gcaaatcgcg acagtgaaat ttgtcatgca atagtctgtt ttgtccctga ttgttgctta
    30541 aactaggttt attttaaaaa aatgttacct tcatcaatag tcaacggccc tgttgctcat
    30601 tataatccgc gccatctcgt acgctggtac agacaacaac agaacaattt acagaggtaa
    30661 aaatggctat tgaacgtact ttttccatca tcaaaccgaa cgcggtagca aaaaacgtca
    30721 ttggtaatat ctttgcgcgc tttgaagctg cagggttcaa aattgtcggc accaaaatgc
    30781 tgcacctgac cgttgaacag gctcgtggct tttatgctga acacgatgga aaaccgttct
    30841 ttgatggtct ggttgaattc atgacctctg gcccgatcgt ggtttccgtg ctggagggtg
    30901 aaaacgccgt tcagcgtcac cgcgatctgc tgggcgcgac caatccggca aacgcactgg
    30961 ccggtactct gcgtgctgat tacgctgaca gcctgaccga aaatggtacc cacggttctg
    31021 attccgtcga atctgccgct cgcgaaatcg cttatttctt cggcgaaggc gaagtgtgcc
    31081 cgcgcacccg ttaataattt cgtaaatgct acgtgcaaac gtggcatccg tgcgccagaa
    31141 tttgtacaat gcagcgcccc cggacgagca gccgctcacc ggggcgtttc ttttttcaac
    31201 cctccagggg ccataacgtg taataacgag gccggaatag catatgtctg aacaattagt
    31261 cacacctgaa aacgtcacca cgaaagatgg aaaaatcaac ctgctggatc tcaaccgtca
    31321 gcagatgcgg gagtttttta aagatttagg tgaaaaaccc ttccgcgccg atcaggtgat
    31381 gaagtggatg tatcactatt gctgcgacaa ctttgatgag atgaccgaca tcaacaaagt
    31441 gttgcgcggc aaactgaaag aggtggcgga gatccgcgca ccggaagtgg ttgaagaaca
    31501 gcgttcatct gacggcacca ttaaatgggc aattgccgtt ggcgatcagc gcgtcgaaac
    31561 ggtgtatatc ccggaagacg accgtgccac gctctgcgtc tcttcgcagg tggggtgtgc
    31621 gctggagtgt aaattctgtt ccactgccca gcagggcttt aaccgcaacc tgcgggtatc
    31681 ggaaattatc ggccaggtgt ggcgtgcagc gaaaatcgtc ggcgcagcaa aagtcaccgg
    31741 tcagcgtcca atcactaacg tagtgatgat gggcatgggc gagccgctgc tcaacctgaa
    31801 caatgtcgtt ccggcgatgg aaatcatgct tgatgatttc ggttttggcc tgtctaaacg
    31861 tcgcgtgacg ctttccactt ccggtgtagt tccggcgctg gataaactgg gcgatatgat
    31921 cgacgttgca ctggcaattt ccctgcacgc gccgaacgac gaaattcgtg acgaaattgt
    31981 gccgatcaac aaaaagtaca atatcgaaac gttccttgct gcggtgcgcc gttatctgga
    32041 gaaatccaac gccaatcagg gccgagtcac tattgaatac gtgatgcttg accacgttaa
    32101 cgacggcact gaacacgcgc accaactggc ggagctactg aaagatacgc cgtgtaagat
    32161 caacctgatc ccgtggaacc cgttcccggg cgcgccgtat ggacgcagtt cgaacagccg
    32221 tatcgaccgt ttctcaaaag tgctgatgag ctacggtttc accactattg tgcgtaaaac
    32281 tcgtggtgat gatatcgatg ctgcctgtgg acagttggcg ggcgatgtta tcgaccgtac
    32341 gaaacgtact ctgcgtaaac ggatgcaggg tgaagccatc gacattaaag cggtctgata
    32401 gccattacgc cacggttact ttatgtaccg tggcgtaatc ttttatgaat gaagtattaa
    32461 gttgcaattg tctggtcaat attaacggtg cgtttttgct gactttaagg cagtatgtaa
    32521 cgatgcaaca gtaagttagc cttagtgaat gtgggctttg tcacgagcac acagacggtc
    32581 ttatactgta tgataacggt taacttaacg gatgtttcgc ggtgtgggtg agcatgatgg
    32641 ttcaccggca tctcaattct catttaaacg tacctgcagc gaatgaatac tgaagccacg
    32701 cacgaccaaa atgaagcact tactaccggc gctcgcctgc gtaatgctcg cgaacaacta
    32761 ggacttagtc agcaggccgt tgccgagcga ctttgcctga aggtttccac ggtacgcgac
    32821 attgaagaag ataaggcacc cgccgatctt gcttcaacat tcctgcgcgg atatatccgc
    32881 tcttatgcgc gtctggtaca tattccagaa gaagaactgc tgccagggct ggaaaagcag
    32941 gctccactac gggctgcaaa agttgcgccg atgcagagtt tttccctcgg taaacgccgc
    33001 aaaaaacgcg acggctggct gatgaccttc acctggctgg tgttgtttgt ggttatcggc
    33061 ctgagcggtg cctggtggtg gcaagaccac aaagctcagc aggaagagat caccactatg
    33121 gccgatcaat cttcggcgga actgagcagt aatagcgagc aggggcagag tgttccgtta
    33181 aatacgtcga caactacaga cccggctaca acgtccacgc cgccagcgtc tgtggatact
    33241 accgcaacca acacgcaaac acctgccgta actgcgccag caccagctgt tgatccgcaa
    33301 cagaatgcgg ttgtttcgcc ttcgcaggca aatgttgata ccgccgcgac cccggcacca
    33361 acggcaacaa caacgccaga tggtgctgcg ccgttgccaa ccgatcaggc tggcgtgacc
    33421 acgccggcgg ctgatccgaa tgcgctggtg atgaacttta ctgccgattg ctggctggag
    33481 gtcactgatg ctaccggtaa aaaactgttt agcgggatgc agcgtaaaga cggtaatttg
    33541 aatttaaccg gccaggcacc gtataaactg aaaattggtg cgccagccgc agtacagatc
    33601 cagtatcaag ggaaacctgt cgatctgagt cgttttatca gaactaacca ggttgcgcgt
    33661 ctgaccctca atgccgaaca atcaccggcg cagtaacaga cgggtaacgc gggagatttt
    33721 tcatgcataa ccaggctcca attcaacgta gaaaatcaac acgtatttac gttgggaatg
    33781 tgccgattgg cgatggtgct cccatcgccg tacagtccat gaccaatacg cgtacgacag
    33841 acgtcgaagc aacggtcaat caaatcaagg cgttggaacg tgttggcgct gatatcgtcc
    33901 gtgtctcagt accgacgatg gacgcggcag aagcgttcaa actcatcaaa cagcaggtta
    33961 acgtgccgct ggtggctgac atccacttcg actatcgcat tgcgctgaaa gtagcggaat
    34021 acggcgtcga ttgtctgcgt attaaccctg gcaatatcgg taatgaagag cgtattcgca
    34081 tggtggttga ctgtgcgcgc gataaaaaca ttccgatccg tattggcgtt aacgccggat
    34141 cgctggaaaa agatctgcaa gaaaagtatg gcgaaccgac gccgcaggcg ttgctggaat
    34201 ccgccatgcg tcatgttgat catctcgatc gcttgaactt cgaacagttc aaagtcagcg
    34261 tgaaagcgtc agacgtcttc ctcgctgttg agtcttatcg tttgctggca aaacagatcg
    34321 atcagccgct gcatctgggg atcaccgaag cgggtggtgc gcgcagcggg gcggttaaat
    34381 ccgccattgg tttaggtctg ctgctgtctg aaggcattgg cgacacgctg cgcgtatcgc
    34441 tggcggccga tccggttgaa gagatcaaag tcggtttcga tattttgaaa tcgctgcgta
    34501 tccgttcgcg cgggatcaac ttcatcgcct gtccaacctg ttcgcgtcag gagtttgatg
    34561 ttatcggtac ggttaacgcg ctggagcaac gcctggaaga tatcatcact ccgatggacg
    34621 tttcgattat cggctgtgtg gtgaatggcc caggtgaggc gctggtttct acactcggcg
    34681 tcaccggcgg taacaagaaa agcggcctct atgaagatgg cgtgcgcaaa gaccgtctgg
    34741 acaacaacga tatgatcgac cagctggaag cgcgcattcg tgcgaaagcc agtcagctgg
    34801 acgaagcgcg tcgaattgac gttcagcagg ttgaaaaata ataacgtgat gggaagcgcc
    34861 tcgcttcccg tgtatgattg aacccgcatg gctcccgaaa cattgaggga agcgttgagg
    34921 gttcattttt atattcagaa agagaataaa cgtggcaaaa aacattcaag ccattcgcgg
    34981 catgaacgat tacctgcctg gcgaaacggc catctggcag cgcattgaag gcacactgaa
    35041 aaacgtgctc ggcagctacg gttacagtga aatccgcttg ccgattgtag agcagacccc
    35101 gctattcaaa cgtgcgattg gtgaagtcac cgacgtggtt gaaaaagaga tgtacacctt
    35161 tgaggatcgc aatggcgaca gcctgactct gcgccctgaa gggacggcgg gctgtgtacg
    35221 cgccggcatc gagcatggtc ttctgtacaa tcaggaacag cgtctgtggt atatcgggcc
    35281 gatgttccgt cacgagcgtc cgcagaaagg gcgttatcgt cagttccatc agttgggctg
    35341 cgaagttttc ggtctgcaag gcccggatat cgacgctgaa ctgattatgc tcaccgcccg
    35401 ctggtggcgc gcgctgggta tctccgagca cgtaactctt gagctgaact ctatcggttc
    35461 gctggaagca cgcgccaatt accgcgatgc gctggtggca ttccttgagc agcataaaga
    35521 aaagctggac gaagactgca aacgccgcat gtacactaac ccgctgcgcg tgctggattc
    35581 aaaaaatccg gaagtgcagg cgcttctcaa cgacgctccg gcattaggcg attatctgga
    35641 cgaggaatct cgtgagcatt ttgccggtct gtgcaaactg ctggagagcg cggggatcgc
    35701 ttacaccgta aaccagcgtc tggtgcgtgg tctggattac tataaccgta ccgttttcga
    35761 gtgggtgact aacagtctcg gctcccaggg caccgtgtgt gcaggcggtc gttatgacgg
    35821 tctggtggaa caactgggcg gtcgtgcaac accggctgtc ggttttgcga tgggcctcga
    35881 acgtcttgta ttgttagtac aggccgttaa tccggaattt aaagccgatc ctgttgtcga
    35941 tatatacctg gtggcttcag gtgctgatac acaatctgcg gctatggcat tagctgagcg
    36001 tctgcgtgat gaattaccgg gcgtgaaatt gatgaccaac cacggcggcg gcaactttaa
    36061 gaaacagttt gcccgtgctg ataaatgggg tgcccgcgtt gctgtggtgc tgggtgagtc
    36121 tgaagtggct aacggcacag cagtagtgaa ggatttgcgc tctggtgagc aaacggcagt
    36181 tgcgcaggat agcgtagccg cgcatttgcg cacgttactg ggttaaggaa ggagaaggac
    36241 agcgtggaaa tttacgagaa cgaaaacgac caggtagaag cggttaaacg cttttttgct
    36301 gaaaatggca aagcactggc tgttggggtg attttgggcg ttggcgcact aattggctgg
    36361 cgctactgga acagccatca ggttgattct gcacgctccg cttctcttgc ctatcaaaat
    36421 gcggttaccg cagtgagcga aggcaaaccg gatagcattc cggcggcgga aaaatttgct
    36481 gctgaaaata aaaatactta tggtgcgctg gcttctttgg aacttgcgca gcaatttgtt
    36541 gacaaaaatg aactagagaa agctgccgcc cagttacaac aggggctggc agacacgagc
    36601 gatgaaaatc tcaaagccgt gataaatctg cgtcttgctc gcgttcaggt acagctcaag
    36661 caggctgatg ccgcgctgaa aacccttgat accatcaaag gtgaagggtg ggctgccatt
    36721 gttgccgacc tgcgtggtga agcattgctg agcaaaggtg ataagcaagg tgcgcgtagt
    36781 gcatgggaag caggcgtgaa aagcgatgtt actccggcac tgagcgaaat gatgcagatg
    36841 aaaattaata atttgtccat ctgagaggga cccgatgcaa ttgcgtaaat tactgctgcc
    36901 aggactgctt tccgttaccc ttttaagcgg ctgttcgctg tttaacagcg aagaagatgt
    36961 ggtaaagatg tccccattgc caaccgttga aaaccagttt acgccgacca cggcgtggag
    37021 cacttccgtt ggtagcggca ttggcaactt ctattccaat cttcatccgg cactggcgga
    37081 caacgttgtc tatgcagcgg accgcgctgg tttagtaaaa gcgctgaatg cggatgatgg
    37141 caaagaaatc tggtctgtca gcctggccga gaaagatggc tggttctcta aagagcctgc
    37201 attactttct ggcggcgtga ccgtgtctgg cgggcatgtc tacattggca gtgaaaaggc
    37261 gcaggtttac gcgctgaata ccagcgatgg tactgtggca tggcaaacta aagtcgcggg
    37321 tgaagcactt tcgcgtccgg tggtcagcga cggtctggtg ttaatccaca ccagtaatgg
    37381 tcagttacaa gcgctgaacg aaaccgacgg cgctgtcaaa tggacagtta acctcgatat
    37441 gccttcgctc tctttgcgtg gcgagtctgc gccggcaacg gcttttggtg cggccgtcgt
    37501 gggtggcgat aatggtcgcg tcagcgcagt gctgatggaa cagggccaga tgatttggca
    37561 gcagcgtatt tcccaggcga ccggttcaac cgaaattgac cgtctgagcg atgttgacac
    37621 gactcccgtc gttgttaacg gcgttgtttt cgcgctggcc tataatggta acctgacggc
    37681 gcttgatctg cgcagcggtc agattatgtg gaaacgcgaa ctgggttcgg tgaatgattt
    37741 catcgtcgac ggcaaccgca tctatctggt cgatcaaaat gaccgggtga tggcgttgac
    37801 cattgatggc ggcgttacgc tgtggacaca aagcgatctg ttgcatcgcc tgctgacttc
    37861 tccggtgctg tataatggca acctggtggt aggtgacagt gaaggttatc tgcactggat
    37921 taacgtcgaa gatggtcgtt tcgttgccca gcaaaaagtt gatagttccg gtttccagac
    37981 tgaaccggtt gccgctgacg gcaaactgct gatccaggca aaagacggaa ccgtgtactc
    38041 tattacacgt taatcgtctc tgtcgttcac tttgaaaacg gctcctggac aggggccgtt
    38101 ttcctgtttt taacaacgac acgaatatag cgtgcgttgt ctgatgattt ataaaaatga
    38161 ggctttaaac atggtacctg tggtcgcgct tgtcgggcgc cctaacgtag gaaaatccac
    38221 gttatttaac cgtctaactc gcacccgaga tgcgctggtt gcggatttcc cgggtctgac
    38281 tcgtgaccgt aagtacggtc gtgcagaaat tgaaggccgt gagtttatct gcattgatac
    38341 cggcgggatt gatggcacag aagacggtgt agaaacccgc atggcggaac agtcgctgct
    38401 ggcgattgaa gaagcggacg tcgtactgtt tatggtggat gcgcgcgcgg gcctgatgcc
    38461 ggcggatgaa gcgattgcta aacatctgcg ctcccgtgaa aaaccgacct tcctggtggc
    38521 aaacaaaact gacggtctgg atcccgatca ggcagtggtt gatttctact cgcttggttt
    38581 aggggaaatc tacccgatcg ccgcgtctca cggtcgtggc gtattaagtc tgcttgagca
    38641 cgtgctgctg ccgtggatgg aagatctcgc accgcaagaa gaagtcgacg aagacgctga
    38701 atactgggcg caatttgaag cagaagaaaa cggcgaagaa gaagaggaag atgacttcga
    38761 cccgcaaagt ctgccgatca aactggcgat tgtgggtcgt ccgaacgtag gtaagtctac
    38821 actcactaac cgtattcttg gtgaagagcg cgttgttgtt tacgacatgc ctggcacgac
    38881 gcgtgacagc atctacattc caatggagcg cgatggacgt gagtatgtac tcattgacac
    38941 cgctggcgta cgtaaacgcg gcaaaatcac cgatgctgta gagaaattct cggtaatcaa
    39001 aacgttgcag gccattgaag atgccaacgt ggtgatgttg gtgattgacg cccgcgaagg
    39061 tatttccgat caggatctct cgctgctggg ctttattctc aatagtgggc gctcacttgt
    39121 cattgtggtg aataagtggg atggcctgag ccaggaagtg aaagagcagg tgaaagaaac
    39181 gctggacttc cgtctgggct ttatcgattt tgctcgtgtg cactttatct ctgccttgca
    39241 cggcagtggt gttggtaacc tgtttgaatc agtgcgtgaa gcgtatgaca gctctacccg
    39301 tcgcgtgggt acgtctatgc tgacccgcat catgaccatg gctgttgaag atcaccagcc
    39361 gccgctggta cgcgggcgtc gcgtgaagct gaaatatgcc cacgccggtg gttataaccc
    39421 gccgattgtg gtgattcacg gtaaccaggt aaaagacctg ccggattcct ataagcgtta
    39481 tctgatgaac tatttccgca agtctctgga tgtgatgggg acgccgattc gtattcagtt
    39541 caaagaaggg gaaaacccgt atgcgaacaa gcgtaacacc ctgacgccga cccagatgcg
    39601 caagcgtaag cgcctgatga agcatatcaa gaaaagtaag taatcactta tttggtttcc
    39661 ctttccacac ggaaagggaa accgaataac gcgcgaggag tatttatggc actcaactgt
    39721 ccaacctgca aaacccctct cgaacgcaat ggcgagactg cccactgtgc aacttgcgac
    39781 aaagacttta ccgtccaggc actttgccct gagtgtcatc agccgttaca agtgttaaaa
    39841 gcttgtggtg ctgtggacta tttctgccaa catgggcacg gtttaatatc taaaaaacgc
    39901 gttgaatttg ttattgctta atatcatgtg aatatattgt tttatcattt atatttaata
    39961 tgtgaatggt aaaacaatct gttattagtg gaat
//
LOCUS       DACAOP010000035        39050 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.035, whole genome shotgun sequence.
ACCESSION   DACAOP010000035 DACAOP010000000
VERSION     DACAOP010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39050
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.035"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..659
                     /locus_tag="IT892_002030"
     CDS             <1..659
                     /locus_tag="IT892_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP3135253.1"
                     /translation="RALIQGLKHDLLADDTALRALIPQRLIAFDDAVRSTLKEEEKLV
                     NSSDWGYDAQAFARWRPEYGYFAKQAGFTVKTSASLAALWQVVNQIGGKERYFFGNIL
                     WQTRALMDRAIGHKLAKGRPEREYLQTGDAVDSWKVIVVEPEKQLTLLFGMKAPGLGR
                     LCFSLEDKGDYRTIDVRAFWHPHGMPGLFYWLLMIPAHLFIFRGMAKQIARLAEQSTD
                     "
     gene            758..1771
                     /locus_tag="IT892_002031"
     CDS             758..1771
                     /locus_tag="IT892_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415389.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAP3135254.1"
                     /translation="MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMG
                     AEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAV
                     AWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
                     TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLA
                     SQEACDKLPSGRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMER
                     LGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDEGIEKTAAWLRDHGK
                     LPR"
     gene            complement(1768..2598)
                     /locus_tag="IT892_002032"
     CDS             complement(1768..2598)
                     /locus_tag="IT892_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP3135255.1"
                     /translation="MRRFFWLVAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRI
                     KVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGI
                     SAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKP
                     ENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVDTASL
                     LELLARYGYDVKPDMTPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
                     "
     gene            complement(2595..2918)
                     /locus_tag="IT892_002033"
     CDS             complement(2595..2918)
                     /locus_tag="IT892_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAP3135256.1"
                     /translation="MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVG
                     GRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTA
                     VKTRR"
     gene            3044..3559
                     /locus_tag="IT892_002034"
     CDS             3044..3559
                     /locus_tag="IT892_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP3135257.1"
                     /translation="MRYSKLTMLIPCALLLSACTTVTPAYKDNGTRSGPCVEGGPDNV
                     AQQFYDYRILHRSNDITALRPYLSDKLATLLSDASRDNNHRELLTNDPFSSRTTLPDS
                     AHVASASTIPNRDARNIPLRVDLKQGDQGWQDEVLMIQEGQCWVIDDVRYLGGSVHAT
                     AGTLRQSIENR"
     gene            3777..4505
                     /gene="artP"
                     /locus_tag="IT892_002035"
     CDS             3777..4505
                     /gene="artP"
                     /locus_tag="IT892_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter ATP-binding protein
                     ArtP"
                     /protein_id="HAP3135258.1"
                     /translation="MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSL
                     LRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQN
                     LIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
                     QVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGH
                     IVEQGDASCFTEPQTEAFKNYLSH"
     gene            4523..5254
                     /gene="artJ"
                     /locus_tag="IT892_002036"
     CDS             4523..5254
                     /gene="artJ"
                     /locus_tag="IT892_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3135259.1"
                     /translation="MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESIDANNQIV
                     GFDVDLAQALCKEIDATCTFSNQAFDSLIPSLKFRRVEAVMAGMDITPEREKQVLFTT
                     PYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
                     LDLQNGRIDGVFGDTAVVTEWLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQ
                     KLNTALEKVKKDGTYETIYNKWFQK"
     gene            5261..5977
                     /gene="artQ"
                     /locus_tag="IT892_002037"
     CDS             5261..5977
                     /gene="artQ"
                     /locus_tag="IT892_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtQ"
                     /protein_id="HAP3135260.1"
                     /translation="MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVA
                     WAGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTINLGFVQIPVQMDIENFDVS
                     PFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRH
                     ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLL
                     SQYILKRIDLRATRFERRPS"
     gene            5977..6645
                     /gene="artM"
                     /locus_tag="IT892_002038"
     CDS             5977..6645
                     /gene="artM"
                     /locus_tag="IT892_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtM"
                     /protein_id="HAP3135261.1"
                     /translation="MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVL
                     VWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNS
                     AAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
                     STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAF
                     ERRN"
     gene            6936..7667
                     /gene="artJ"
                     /locus_tag="IT892_002039"
     CDS             6936..7667
                     /gene="artJ"
                     /locus_tag="IT892_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3135262.1"
                     /translation="MKKLVLAALLASFTFGASAAEKINFGISATYPPFESIGANNEIV
                     GFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTT
                     PYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAF
                     IDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLE
                     KLNNALAAIKADGTYQKISDQWFPQ"
     gene            complement(7866..8993)
                     /gene="rlmC"
                     /locus_tag="IT892_002040"
     CDS             complement(7866..8993)
                     /gene="rlmC"
                     /locus_tag="IT892_002040"
                     /EC_number="2.1.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /protein_id="HAP3135263.1"
                     /translation="MQCALYDAGRCRSCQWIMQPIPEQLSAKTADLKNLLADFPVEEW
                     CAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGTPEDLCDCPLYPASFAPVFAALK
                     PFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSDTKLAQLRKALPWLHE
                     QLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALAERFNDVPLWIRPQSFFQTNPAVA
                     SQLYATARDWVRQLPVKHMWDLFCGVGGFGLHCATPDMQLTGIEIASEAIACAKQSAA
                     ELGLTRLQFQALDSTQFATAQGDVPELVLVNPPRRGIGKPLCDYLSTMAPRFIIYSSC
                     NAQTMAKDIRELPGFRIERVQLFDMFPHTAHYEVLTLLVKQ"
     gene            complement(9034..9522)
                     /locus_tag="IT892_002041"
     CDS             complement(9034..9522)
                     /locus_tag="IT892_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjO family protein"
                     /protein_id="HAP3135264.1"
                     /translation="MEDETLGFFKKTSSSHARLNVPALVQVAALAIIMIRGLDVLMIF
                     NTLGVRGIGEFIHRSVQTWSLTLVFLSSLVLVFIEIWCAFSLVKGRRWARWLYLLTQI
                     TAASYLWAASLGYGYPELFSIPGESKREIFHSLMLQKLPDMLILMLLFVPSTSRRFFQ
                     LQ"
     gene            complement(9582..10427)
                     /gene="potI"
                     /locus_tag="IT892_002042"
     CDS             complement(9582..10427)
                     /gene="potI"
                     /locus_tag="IT892_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotI"
                     /protein_id="HAP3135265.1"
                     /translation="MNNLPVVRSPWRIVILLLGFTFLYAPMLMLVIYSFNSSKLVTVW
                     AGWSTRWYGELLRDDAMMSAVGLSLTIAACAATAAAILGTIAAVVLVRFGRFRGSNGF
                     AFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVIS
                     SRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFV
                     SGPGATTLPMLVFSSVRMGVNPEINALATLILGAVGIVGFIAWYLMARAEKQRIRDIQ
                     RARRG"
     gene            complement(10424..11377)
                     /gene="potH"
                     /locus_tag="IT892_002043"
     CDS             complement(10424..11377)
                     /gene="potH"
                     /locus_tag="IT892_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotH"
                     /protein_id="HAP3135266.1"
                     /translation="MSTLEPAAQSKPPGGFKLWLSQLQMKHGRKLVIALPYIWLILLF
                     LLPFLIVFKISLAEMARAIPPYTELMEWADGQLSITLNLGNFLQLTDDPLYFDAYLQS
                     LQVAAISTFCCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKN
                     NGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYVPFMVLPIYTALIRIDYSLVEAA
                     LDLGARPLKTFFTVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQ
                     EFFNNRDWPVASAVAIIMLLLLIVPIMWFHKHQQKSVGEHG"
     gene            complement(11387..12520)
                     /gene="potG"
                     /locus_tag="IT892_002044"
     CDS             complement(11387..12520)
                     /gene="potG"
                     /locus_tag="IT892_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter ATP-binding subunit
                     PotG"
                     /protein_id="HAP3135267.1"
                     /translation="MNDAIPRPQAKTRKALTPLLEIRNLTKSYDGQHAVDDVSLTIYK
                     GEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDGVDLSQVPPYLRPINMMFQSYAL
                     FPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
                     ARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAG
                     RIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGVLKERQEDGLVLDSPGLV
                     HPLKVDADASVVDNVPVHVALRPEKIMLCEEPPANGCNFAVGEVIHIAYLGDLSVYHV
                     RLKSGQMISAQLQNAHRHRKGLPTWGDEVRLCWEVDSCVVLTV"
     gene            complement(12615..13727)
                     /gene="potF"
                     /locus_tag="IT892_002045"
     CDS             complement(12615..13727)
                     /gene="potF"
                     /locus_tag="IT892_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotF"
                     /protein_id="HAP3135268.1"
                     /translation="MTALNKKWLSGLVAGALMAVSVGTLAAEQKTLHIYNWSDYIAPD
                     TVANFEKETGIKVVYDVFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLD
                     KSKLPEWKNLDPELLKLVAKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSW
                     DLILKPENLEKLKSCGVSFLDAPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLR
                     PNIRYFHSSQYINDLANGDICVAIGWAGDVWQASNRAKEAKNGVNVSFSIPKEGAMAF
                     FDVFAMPADAKNKDEAYQFLNYLLRPDVVAHISDHVFYANANKAATPLVSAEVRENPG
                     IYPPADVRAKLFTLKVQDPKIDRVRTRAWTKVKSGK"
     gene            complement(14078..14554)
                     /locus_tag="IT892_002046"
     CDS             complement(14078..14554)
                     /locus_tag="IT892_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjN domain-containing protein"
                     /protein_id="HAP3135269.1"
                     /translation="MTSLVVPGLDTLRQWLDDLGMSFFECDNCQALHLPHMQNFDGVF
                     DAKIDLIDNTILFSAMAEVRPSAVLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVC
                     QSLSVMQGVTYEQFAWFVRQSEEQISMVILEANAHQLLLPTDDEGQNNVTENYFLH"
     gene            complement(14642..15544)
                     /gene="rimK"
                     /locus_tag="IT892_002047"
     CDS             complement(14642..15544)
                     /gene="rimK"
                     /locus_tag="IT892_002047"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6--L-glutamate ligase"
                     /protein_id="HAP3135270.1"
                     /translation="MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPA
                     ASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLR
                     SMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAA
                     ESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGG
                     AASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGI
                     DIAGKMIRWIERHATTEYCLKTGG"
     gene            complement(15605..16327)
                     /gene="nfsA"
                     /locus_tag="IT892_002048"
     CDS             complement(15605..16327)
                     /gene="nfsA"
                     /locus_tag="IT892_002048"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase NfsA"
                     /protein_id="HAP3135271.1"
                     /translation="MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQ
                     CSSIIRITDNALREELVTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLL
                     LGVVDTAMMAQNALIAAESLGLGRVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP
                     ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRR
                     TIIKESRPFILDYLHKQGWATR"
     gene            complement(16311..16598)
                     /locus_tag="IT892_002049"
     CDS             complement(16311..16598)
                     /locus_tag="IT892_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1418 family protein"
                     /protein_id="HAP3135272.1"
                     /translation="MRAIGKLPKGVLILEFIGMMLLAVALLSVSDSLSLPEPFSRPEV
                     QILMIFLGVLLMLPAAVVVILQVAKRLAPQLMNRPPQYSRSEREKDNDANH"
     gene            16758..17015
                     /gene="grxA"
                     /locus_tag="IT892_002050"
     CDS             16758..17015
                     /gene="grxA"
                     /locus_tag="IT892_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 1"
                     /protein_id="HAP3135273.1"
                     /translation="MQTVIFGRSGCPYCVRAKDLAEKLSNERDDFQYQYVDIRAEGIT
                     KEDLQQKAGKPVETVPQIFVDQQHIGGYTDFAAWVKENLDA"
     gene            complement(17045..17422)
                     /locus_tag="IT892_002051"
     CDS             complement(17045..17422)
                     /locus_tag="IT892_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135274.1"
                     /translation="MKHKQRWAGAICCFVLFIVVCLFLATHMKGAFRAAGHPEIGLLF
                     FILPGAVASFFSQRREVLKPLFGAMLAAPCSMLIMRLFFSPTRSFWQELAWLLSAVFW
                     CALGALCFLFISSLFKPQHRKNQ"
     gene            17692..19377
                     /locus_tag="IT892_002052"
     CDS             17692..19377
                     /locus_tag="IT892_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine antiporter"
                     /protein_id="HAP3135275.1"
                     /translation="MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVL
                     VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGS
                     ALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLS
                     LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAY
                     RVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYP
                     DAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRV
                     IRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVI
                     GLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLM
                     VFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGA
                     MMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG"
     gene            complement(19552..20088)
                     /locus_tag="IT892_002053"
     CDS             complement(19552..20088)
                     /locus_tag="IT892_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP3135276.1"
                     /translation="MRRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGS
                     MTYYFSGIDELLLEAFSSFTEIMSRQYQAFFSDVSDAPGACQAITDMIYSSQVATPDN
                     MELMYQLYALASRKPLLKTVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTD
                     RKPLSREEILRMVERVAG"
     gene            20172..21380
                     /locus_tag="IT892_002054"
     CDS             20172..21380
                     /locus_tag="IT892_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3135277.1"
                     /translation="MTVNSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSV
                     SIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTMSCALIGMMILSLALWLTS
                     PLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMA
                     LTAFGVPATVHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQHGEKGVPFYRDIQLL
                     LIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFID
                     RYSRVAVVRASALMGALGIGLIIFVDSAWVAGVSVVLWGLGASLGFPLTISAASDTGP
                     DAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMLVVLALVILAAIVAKAVAKPD
                     TKTQTAMENS"
     gene            21380..22195
                     /gene="ybjI"
                     /locus_tag="IT892_002055"
     CDS             21380..22195
                     /gene="ybjI"
                     /locus_tag="IT892_002055"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415365.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase"
                     /protein_id="HAP3135278.1"
                     /translation="MSIKLIAVDMDGTFLSDQKTYNRERFMAQYQQMKAQGIRFVVAS
                     GNQYYQLISFFPEIANEIAFVAENGGWVVSEGKDVFNGELSKDAFATVVEHLLTRPEV
                     EIIACGKNSAYTLKKYDDAMKTVAEMYYHRLEYVDNFDNLEDIFFKFGLNLSDELIPQ
                     VQKALHEAIGDIMVSVHTGNGSIDLIIPGVHKANGLRQLQKLWGIDDSEVVVFGDGGN
                     DIEMLRQAGFSFAMENAGSAVVAAAKYRAGSNNREGVLDVIDKVLKHEAPFDQ"
     gene            22281..22565
                     /locus_tag="IT892_002056"
     CDS             22281..22565
                     /locus_tag="IT892_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135279.1"
                     /translation="MIMKNCLLLGALLMGFTGVAMAQSVTVDVPSGYKVVVVPDSVSV
                     PQAVSVATVPQTVYVAPAPAPAYRPHPYVRHLASVGEGMVIEHQIDDHHH"
     gene            complement(22606..23838)
                     /gene="mdfA"
                     /locus_tag="IT892_002057"
     CDS             complement(22606..23838)
                     /gene="mdfA"
                     /locus_tag="IT892_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdfA"
                     /protein_id="HAP3135280.1"
                     /translation="MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVV
                     EQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLA
                     QNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
                     GAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKN
                     GRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLA
                     RLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGL
                     VRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWL
                     SLMVIFLKDKQMGNSHEG"
     gene            24123..24719
                     /gene="ybjG"
                     /locus_tag="IT892_002058"
     CDS             24123..24719
                     /gene="ybjG"
                     /locus_tag="IT892_002058"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAP3135281.1"
                     /translation="MLENLNLSLFSLINATPDSAPWMISLAIFIAKDLITVVPLLAVV
                     LWLWGLTAQRQLVIKIAIALAVSLFVSWTMGHLFPHDRPFVENIGYNFLHHAADDSFP
                     SDHGTVIFTFALAFLCWHRLWSGSLLMVLAVVIAWSRVYLGVHWPLDMLGGLLAGMIG
                     CLSAQIIWQAMGHKLYQRLQSWYRVCFALPIRKGWVRD"
     gene            24777..25535
                     /gene="deoR"
                     /locus_tag="IT892_002059"
     CDS             24777..25535
                     /gene="deoR"
                     /locus_tag="IT892_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor DeoR"
                     /protein_id="HAP3135282.1"
                     /translation="METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNN
                     HSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAKLAATLVEPDQTLFFDCGT
                     TTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQT
                     LNNFCPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPA
                     RMGDLKRFDIVVSDCCPEDEYVKYAQTQRIKLMY"
     gene            complement(25582..26784)
                     /gene="dacC"
                     /locus_tag="IT892_002060"
     CDS             complement(25582..26784)
                     /gene="dacC"
                     /locus_tag="IT892_002060"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HAP3135283.1"
                     /translation="MTQYSSLLRGLAAGSAFLFLFAPTAFAAEQTVEAPSVDARAWIL
                     MDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGN
                     PALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAK
                     KLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQP
                     NRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEK
                     LLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLKASY
                     TLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGGFFGRVWDFVMMKFH
                     QWFGSWFS"
     gene            27031..27657
                     /locus_tag="IT892_002061"
     CDS             27031..27657
                     /locus_tag="IT892_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308945.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HAP3135284.1"
                     /translation="MITLWGRNNSTNVKKVLLTLEELELPYEQILAGREFGINHDADF
                     LAMNPNGLVPLLRDDESDLILWESNAIVRYLAAQYGQKRLWIDSPARRAEAEKWMDWA
                     NQTLSNAHRGILMGLVRTPPEERDQAAIDASCKECDALFALLDAELAKVKWFSGDEFG
                     VGDIAIAPFIYNLFNVGLTWTPRPNLQRWYQQLTERPAVRKVVMIPVS"
     gene            complement(27654..28769)
                     /locus_tag="IT892_002062"
     CDS             complement(27654..28769)
                     /locus_tag="IT892_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="HAP3135285.1"
                     /translation="MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLP
                     DNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWL
                     SYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
                     FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQG
                     MAMNPWSNALWLNEHGPRGGDEINIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAG
                     TEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRI
                     LTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN"
     gene            complement(28880..29263)
                     /gene="bssR"
                     /locus_tag="IT892_002063"
     CDS             complement(28880..29263)
                     /gene="bssR"
                     /locus_tag="IT892_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssR"
                     /protein_id="HAP3135286.1"
                     /translation="MFVDRQRIDLLNRLIDARVDLAAYVQLRKAKGYMSVSESNHLRD
                     NFFKLNRELHDKSLRLNLHLDQEEWSALHHAEEALATAAVCLMSGHHDCPTVITVNAD
                     KLENCLMSLTLSIQSLQKHAMLEKA"
     gene            29476..30801
                     /gene="rimO"
                     /locus_tag="IT892_002064"
     CDS             29476..30801
                     /gene="rimO"
                     /locus_tag="IT892_002064"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HAP3135287.1"
                     /translation="MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDD
                     ADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITG
                     PHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
                     SMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTS
                     MVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMK
                     RPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCF
                     KYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDE
                     EGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV"
     gene            complement(30848..32176)
                     /locus_tag="IT892_002065"
     CDS             complement(30848..32176)
                     /locus_tag="IT892_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HAP3135288.1"
                     /translation="MSRINKFVLTVSLLIFIMISAVACGIYTQMVKERVYSLKQSVID
                     TAFAVANIAEYRRSVAIDLINTLNPTEEQLLVGLRTAYADSVSPSYLYDVGPYLISSD
                     ECIQVKEFEKNYCADIMQVVKYRHVKNTGFISFDGKTFVYYLYPVTHNRSLIFLLGLE
                     RFSLLSKSLAMDSENLMFSLFKNGKPVTGDEYNAKNAIFTVSEAMEHFAYLPTGLYVF
                     AYKKDVYLRVCTLIIFFAALVAVISGASCLYLVRRVINRGIVEKEAIINNHFERVLDG
                     GLFFSAADVKKLYSMYNSAFLDDLTKAMGRKSFDEDLKALPEKGGYLCLFDVDKFKNI
                     NDTFGHLLGDEVLMKVVKILKSQIPVDKGKVYRFGGDEFAVIYTGGTLEELLSILKEI
                     VHFQVGSINLSTSIGVAHSNECPTVERLKMLADERLYKSKKNGRAQISWQ"
     gene            complement(32184..34532)
                     /locus_tag="IT892_002066"
     CDS             complement(32184..34532)
                     /locus_tag="IT892_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAP3135289.1"
                     /translation="MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRAD
                     SRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVL
                     DDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSW
                     NPAYNCFDRPGKKCISFTLHINGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLF
                     LKQGHEIIAKNQLAREKLIIYNSEDNYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPG
                     GNLLNASDKLFYLPFAFIIIVLLVVYLMTTRVFRRQFSEMTELVNTLAFLPDSTDQIE
                     ALKIREGDAKEIISIKNSIAEMKDAEIERSNKLLSLISYDQESGFIKNMAIIESNNNQ
                     YLAVGIIKLCGLEAVEAVFGVDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCR
                     ENVQTFTRKIAMVNDFDSSFGYRNLRIHKSAICEPLQGENAWSYAEKLKLAISSIRDH
                     MFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRAILGAEALCR
                     WVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSQRASLKDDFLLHINV
                     SPWQLNEPHFHERFTTIMKENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRI
                     SIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAGKIVRIIFDLARYNRIPVIAE
                     GVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE"
     gene            complement(34710..35621)
                     /gene="gsiD"
                     /locus_tag="IT892_002067"
     CDS             complement(34710..35621)
                     /gene="gsiD"
                     /locus_tag="IT892_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiD"
                     /protein_id="HAP3135290.1"
                     /translation="MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAA
                     LFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQ
                     ISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVL
                     GSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTVLLRHILPGT
                     VSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPA
                     LAIFLTVLAFNLLGDGLRDALDPKIKG"
     gene            complement(35624..36544)
                     /gene="gsiC"
                     /locus_tag="IT892_002068"
     CDS             complement(35624..36544)
                     /gene="gsiC"
                     /locus_tag="IT892_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiC"
                     /protein_id="HAP3135291.1"
                     /translation="MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEAD
                     AQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLT
                     ITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELG
                     WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWV
                     VLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQA
                     EILLFSLEFILINLVVDVLYAAINPAIRYK"
     gene            complement(36562..38100)
                     /gene="gsiB"
                     /locus_tag="IT892_002069"
     CDS             complement(36562..38100)
                     /gene="gsiB"
                     /locus_tag="IT892_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein GsiB"
                     /protein_id="HAP3135292.1"
                     /translation="MARAVHRSGLVALGIATALMASCAFAAKDVVVAVGSNFTTLDPY
                     DANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGITYTVKLREGIKFQDGT
                     DFNAAAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAH
                     PATAMISPAALEKYGKEIGFYPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSI
                     TWRPVADNNTRAAMLQTGEAQFAFPIPYEQATLLEKNKNIELMASPSIMQRYISMNVT
                     QKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAYAQSYKPWPYDPVKA
                     RELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEV
                     EGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQ
                     ALKTNDPAEKTRLYKAAQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFED
                     ADLQ"
     gene            complement(38120..>39050)
                     /locus_tag="IT892_002070"
     CDS             complement(38120..>39050)
                     /locus_tag="IT892_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP3135293.1"
                     /translation="RVRNLVTRFPLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGE
                     SGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRDIQFIFQDPYASLDP
                     RQTIGDSIIEPLRVHGLLPGKDAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICI
                     ARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISH
                     RVAVMYLGQIVEIGPRRAVFENPQHPYTRKLLAAVPVAEPSRQRPQRVLLSDDLPSNI
                     HLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR"
BASE COUNT         9818 a        10238 c         9490 g         9504 t
ORIGIN      
        1 ccagggcgtt gattcagggg ctgaaacacg atctgctggc ggatgatacc gcgctacgtg
       61 cactcatccc acaacggctg atcgctttcg atgacgcggt acgtagcacg ttgaaagagg
      121 aggaaaaact ggtcaactcc agcgactggg gctacgacgc tcaggccttt gcccgctggc
      181 gaccggagta cggttatttt gccaaacagg cggggtttac cgttaaaacg tccgccagcc
      241 ttgctgcttt atggcaggta gtgaaccaaa tcggcggtaa agagcgttat ttctttggca
      301 atattttgtg gcagacacgg gcgttgatgg accgcgcgat cggtcataag ctggcgaaag
      361 gccgcccgga gcgcgaatat ttacagactg gcgatgcggt ggatagctgg aaagtgattg
      421 tcgttgaacc ggaaaaacaa cttacgttgt tatttggcat gaaagcgccg gggctgggac
      481 gactgtgttt tagcctggaa gataaaggcg actatcgtac tatcgatgtc cgcgctttct
      541 ggcatccgca cggtatgccg gggctgtttt actggttatt gatgatcccc gcgcatctgt
      601 ttatttttcg cggaatggca aaacaaatcg ccagactggc agaacaaagc acagattaat
      661 cgacaaaacc tgcgttattc tttcatgttt cccattgcat catgggggaa atcacggaag
      721 aatgcgcacg ttattttctc aacaacagtg gattgatatg aaggtactgg ttaccggcgc
      781 caccagcggc ttaggtcgaa acgcggtaga gtttttatgc cagaaaggca tcagcgtgcg
      841 agcgaccggt cgcaacgagg caatgggcaa attgctggaa aaaatgggcg cagagtttgt
      901 tccggcggat ctgaccgagc tggtttcatc acaagctaaa gtgatgctcg cgggcattga
      961 tacgctgtgg cactgctcca gctttacctc accctggggg acacaacagg ctttcgatct
     1021 ggctaacgtt cgcgccactc gccgcctggg tgaatgggct gtcgcctggg gtgtgcgtaa
     1081 ctttattcat atctcttccc cctccctgta cttcgattat caccaccatc gcgatattaa
     1141 agaagatttt cgccctcacc gcttcgccaa cgagtttgcc cgcagcaaag cagccagcga
     1201 agaagtgatc aatatgcttt cgcaggcgaa tccacaaacg cgctttacta ttctgcgccc
     1261 acaaagtctg ttcggaccgc acgataaagt ctttattccc cgtctggcgc atatgatgca
     1321 ccactacggc agtattctgt taccgcatgg cggcagtgcg ctggtcgata tgacctacta
     1381 tgaaaatgcc gtgcacgcaa tgtggctggc aagccaggaa gcctgcgata agctaccttc
     1441 cgggcgtgtg tacaacatca ccaacggcga gcatcgcaca ctgcgcagca tcgtgcagaa
     1501 gctgatcgac gagttgaata ttgactgtcg tattcgttcc gtcccctacc cgatgctgga
     1561 tatgatcgcc cgcagcatgg agcgtttagg ccgcaagtca gcaaaagagc cgccgctgac
     1621 ccactacggc gtctccaagt tgaattttga ctttacgctg gatattacgc gtgcgcagga
     1681 agagttaggt tatcagccgg tcatcaccct ggatgaaggt atcgagaaaa ctgccgcctg
     1741 gctacgcgac cacggaaaac tgccgcgcta atcctgcccg tatttctcca gcaatgcttc
     1801 ggcaatcgcc tgagtttctg catccgcttc gccgttatat aacgtcgggc ggaaatgcat
     1861 ctggaatgcc ataatcacgc gccgctgctc gcgcggtgtc atatcaggtt taacgtcata
     1921 accgtagcgc gccaaaagct ccagcaatga cgcggtatct accggtgtgt gcggcgcgcg
     1981 cccggcaagg taaaagttaa cccgctgcgc atccggccag gcaccaatcc cctgctgcgc
     2041 cagttgctgc cagggaaata atggccccgg atcgtctttg cgctgcggtg cgatatccgc
     2101 atgtgccact acgttttccg gcttgatgtg ataacgggca ataatatctt tcgccagtgg
     2161 aataagcgcc tgaatctgtg ccggttcaaa cggggcaaaa tatttcactc cggccgattt
     2221 ttgccagcca cggttttcca gctcaatgcc aatagaggtg tcgttaaggc gcgttgcccc
     2281 gcgccaggcg ctaatccccg catgccaggc cagttcttgt tccggcacca gttgccagat
     2341 gcgcggttta ccgttgtatc gcggtggtac cgcaggaacc agataatgcg agctgacctg
     2401 cttatcggtc agtgtcgcca gcgagctatc aaaatcatct gcggtgtagt ggatcaccag
     2461 cactttaatg cgcggatacg ccgcctgcgc ctggcgtcgg gtatcaagct gatatccctc
     2521 tttctcgaca atgccttttt cgcctgcaca ccctgccaat aacagagcgg cagcgaccag
     2581 ccagaagaat cttctcatcg acgcgttttc accgccgtac cgctgacgct aaccatcagc
     2641 atactgccgt tttgcccgac cgtttcgtag tcgatatcaa taccgacgac ggcatcggcc
     2701 cccagcgccc gcgcctggga gcctaattcc tcaaaggcga tctcccgtgc tttacgcagt
     2761 tctttttcat acgcaccgga acgtccgcca acgatatcgc ggataccggc aaagaaatca
     2821 cggaaaatat tggcacctaa aatcgcttcg ccggtcacca caccgcaata ttcaacgatg
     2881 gtctggcctt ccagagttgg ggttgtagaa aattgcatga tcgatctcct tgtttgctaa
     2941 gccttcgatc tcaaaagcat tatcagactg atacgctatt attgaaagga tatcattatt
     3001 atcgtagaac gctttcagag cgatcgctta taaggaaatc attatgcgct acagcaaatt
     3061 gacaatgctt atcccctgcg cactgctcct cagtgcctgc accacagtca ctccagctta
     3121 taaagataac ggcacacgca gtggtccttg cgttgaagga ggcccggata acgtggccca
     3181 gcaattttat gactaccgca ttttgcaccg cagcaacgac atcaccgcct tgcgccctta
     3241 tctgagcgac aaactggcga cactgcttag cgatgcctcc cgggataata accatcggga
     3301 actactgacc aacgatccat tctccagtcg aaccaccttg ccagatagcg cccacgttgc
     3361 cagtgcatcg actatcccta atcgtgatgc ccgtaacatt ccattgcgcg tggatctcaa
     3421 acagggtgac cagggttggc aggatgaagt gttaatgatt caggaaggcc agtgttgggt
     3481 catcgacgat gtgcgttact taggcggtag cgttcatgcc acggcgggta cgctccgtca
     3541 gtccatcgag aatcgctaac gccttgatca accaataaac cccgtaaatt gtccggcatt
     3601 tcgtgaggaa tgccgacatt tatgctcgcc gaccaccgcc cccgttattt tgtgctatgt
     3661 ttattgaata atgcgctttg cttttaactt ttaaagcaga aatattgcat aattattctg
     3721 tcaaaggtac tatcttcgac ctcaatagct atcagactgc cagtatacga gtgtcaatga
     3781 gtattcaatt aaacggcatt aattgcttct acggcgcgca tcaggcgctg ttcgatatca
     3841 cgctggattg cccacagggc gaaacgctgg tgttacttgg ccccagcggc gcgggtaaaa
     3901 gctcgctgct gcgtgtactc aatctgcttg agatgccgcg ctccggtacg ctcaacattg
     3961 caggcaacca tttcgatttc accaaaacac cctctgacaa agcgattcgc gatttgcgtc
     4021 gtaacgttgg catggtgttt cagcaataca acctgtggcc gcatctgacc gtgcagcaaa
     4081 acctgattga agcgccctgc cgtgtactgg ggttgagtaa agatcaggcg ctggcccgtg
     4141 cagaaaaact gctggaacgt ctgcgtctca aaccttatag cgatcgttac ccgctgcatc
     4201 tttctggtgg tcagcagcag cgtgttgcta ttgcccgtgc gttgatgatg gaaccgcagg
     4261 tactgctgtt cgatgaaccg accgccgcac tggacccgga aattacggca caaatcgtca
     4321 gcatcattcg tgagctggca gaaacgaata ttacccaggt gatcgtcacc cacgaagttg
     4381 aagtggcgcg taaaaccgcc agccgagtgg tgtatatgga aaatggtcat atcgtagaac
     4441 aaggcgacgc gagctgcttt accgagccgc aaaccgaagc atttaaaaac tatctctctc
     4501 actaagattc gggataacaa caatgaaaaa agttctgatt gccgcgttaa ttgcaggttt
     4561 tagtctttcc gccacagctg ccgaaaccat tcgttttgct accgaagcct cctatcctcc
     4621 gtttgaatcg attgatgcaa acaaccagat cgttggtttt gacgtcgacc tggcacaagc
     4681 gctgtgtaaa gagattgatg caacctgcac tttctctaac caggcgtttg acagcctgat
     4741 cccaagcctg aaattccgtc gcgtagaagc cgtgatggcg ggcatggata tcactccgga
     4801 gcgtgaaaag caggtgctgt ttaccacccc gtactatgac aactctgccc tgtttgtggg
     4861 tcagcaaggc aaatacacca gtgttgatca gctgaaaggc aaaaaagtcg gcgtacagaa
     4921 cgggacgaca caccagaaat tcattatgga taagcacccg gaaatcacta ccgttccgta
     4981 tgacagctac cagaacgcaa aactggatct gcaaaacggg cgtatcgacg gcgtcttcgg
     5041 tgacaccgca gtggtcactg agtggctgaa agataacccg aaactggcgg cggtgggcga
     5101 caaagtgacc gataaagatt acttcggcac tggcctcggc atcgcggtac gtcagggcaa
     5161 cactgagctg cagcagaaac tcaacactgc gctggaaaaa gtgaagaaag atggcactta
     5221 cgaaaccatc tacaacaaat ggttccagaa gtaattcctg atgaatgaat tttttccttt
     5281 agcaagcgcc gccgggatga ccgtcggcct tgccgtttgt gcattgattg tcgggctggc
     5341 gctggcgatg ttctttgcgg tatgggagtc ggcaaaatgg cgtcctgtcg cgtgggcagg
     5401 ttcagcgctg gtaaccattc tgcgtggcct gccagaaatt ctggtggtgc tgtttatcta
     5461 ttttggctcc tcgcagctgc tgctgacgct ttcggatggc ttcactatca atcttgggtt
     5521 cgtgcagatc ccagtgcaga tggacattga gaacttcgac gttagcccgt tcctttgtgg
     5581 tgtcatcgct ctgtcactgc tgtatgccgc ctatgcctcg caaacgcttc ggggcgcgtt
     5641 gaaagcggtg ccggtgggtc agtgggagtc tggtcaggcg ctggggctgt cgaaatcggc
     5701 tatctttttc cgtctggtga tgccgcagat gtggcgtcat gcgctgcctg gcctcggtaa
     5761 ccagtggctg gtgctgctga aagataccgc gctggtcagt ttgattagtg tgaatgattt
     5821 aatgctgcaa acaaaaagca tcgctactcg tacccaggaa ccatttacct ggtacattgt
     5881 ggcggcggcg atttacctgg tgatcaccct gctcagtcag tacattctca aacgcattga
     5941 cctgcgcgcg acacgttttg agcggaggcc cagctaatgt ttgagtattt acccgaactg
     6001 atgaaagggc tacacaccag cctgacgcta accgttgcct cgctgattgt ggcactgatt
     6061 ctggcattga tttttaccat catcctgacg ctgaaaacgc cggtgctggt gtggctggtg
     6121 cggggttata tcacgctgtt taccggtacg ccgctgctgg tgcagatctt cctgatttat
     6181 tacgggccgg gccagtttcc gactttgcag gagtatccgg cactgtggca tttgttgtca
     6241 gaaccgtggt tatgtgcgct gattgcgttg tcgctgaata gtgcggcgta taccacgcag
     6301 ctgttttacg gtgcaattcg tgcgatcccg gaaggtcagt ggcagtcctg tagcgccctg
     6361 ggaatgagca aaaaagatac gctggcgatc ctgctgccgt atgcctttaa acgctcgctc
     6421 tcttcttatt ccaacgaagt ggtgctggta ttcaaaagta cctctctggc atacaccatt
     6481 acgctgatgg aagtgatggg atacagccag ttgttgtacg gacgcaccta cgatgtaatg
     6541 gtgttcggtg cggcagggat tatttacctg gtcgttaacg gcctgctgac gctgatgatg
     6601 cgtctgatcg agcgcaaagc gctggcattc gaacggcgaa attaatgtgg ctgcgtacat
     6661 tcgccggggg gttttgtagg tctgataaga cgcgccagcg tcgcatcaga catcagcacg
     6721 gtgcctgtgc cggatgcggc ggggacgcct tatccggcct acatagtgca taaattctta
     6781 taatgaagac ggacaaccca ctaagttgtc cgtctttttt atttcattta aattatttaa
     6841 tcatgtttat tgcatataaa ttcacttgat ggcattgtta tcccatgccg cagacacggc
     6901 caaaaatcat aagattgaca gacgggagtt ccatcatgaa aaagttagtt cttgccgctt
     6961 tacttgcttc ctttactttc ggtgcttctg ccgcagagaa aatcaatttt ggcatttcag
     7021 ccacctatcc accctttgaa tctataggtg ctaataatga gattgtcggc tttgatatcg
     7081 atctggcaaa agccttgtgc aaacaaatgc aggcagaatg tacttttact aatcacgcgt
     7141 tcgacagcct gatcccgtcc ctgaaattca gaaaatatga cgccgtaatc tccggtatgg
     7201 atatcacccc ggagcgtagc aaacaggtat cgtttaccac gccctactat gaaaactcag
     7261 ccgtcgtgat tgccaaaaaa gatacctaca aaacgtttgc cgatctgaaa ggcaaacgta
     7321 ttgggatgga aaacggtact acgcaccaga aatatattca ggatcagcac ccggaagtga
     7381 aaactgtctc ttatgacagt tatcagaatg cctttatcga tctgaaaaat ggtcgtattg
     7441 atggggtatt tggtgacaca gcggtggtaa acgaatggct gaaaaccaat ccacaacttg
     7501 gtgttgctac tgagaaagtg accgatccgc aatattttgg caccggcctg ggcatcgctg
     7561 tacgtccgga taacaaagcc ctgctggaaa aactgaataa cgcgctggca gcaattaaag
     7621 ctgacggtac ttatcaaaaa atcagtgacc agtggttccc acagtaagat tcagaaagcc
     7681 gcaaccgcgg cttgagactg atgacaaagg taaaattgcc tgatgcgcta cgcttatcag
     7741 gcctacatgg cccatgcaat gtattgaatt tgcacgcttt tgtaggccgg ataaggcgtt
     7801 tacgccgcat ccggcataaa caacgcgcac tttgtcagca atctgaagcc gcacatgcgg
     7861 cttttttatt gcttcaccag cagcgtcagc acttcatagt gcgcggtatg cgggaacata
     7921 tcgaaaagct gcacccgttc aatacgaaac ccaggcagtt cgcggatatc tttcgccata
     7981 gtttgggcgt tacagctgga gtagatgata aaacgcggtg ccatcgttga gagataatca
     8041 cacagcggtt taccaatgcc gcggcgcggc gggttaacca gcaccagctc cggcacatcc
     8101 ccctgagcgg tggcaaactg agtggagtcc agcgcctgaa attgcaaacg cgttaagccc
     8161 agttcagcgg ctgactgctt tgcacaggca atggcctctg atgcaatttc gatcccggtt
     8221 aactgcatgt caggcgtcgc gcagtgtaaa ccaaagcccc ccacaccgca gaacagatcc
     8281 cacatatgtt taaccggcag ctgtcgtacc cagtcgcgcg cggtggcgta caactggctg
     8341 gcgaccgccg gattagtctg gaagaaactt tgcggacgga tccacagcgg tacgtcatta
     8401 aaacgctccg ccagtgcctg ttgttcggtc aggtagatct ccgtctcccc ttccataatc
     8461 gccatatgta ccggctgaat attgacggta ataactttca gctgcggtag ttgttcgtgt
     8521 aaccacggca gcgccttacg cagttgcgcc agcttggtat cagaacgcag tacaaagcgc
     8581 agcatcatgc ctccatcact ctggctttca gtcagcagaa tgtatttcag ttcgccacgc
     8641 ttacgcgcca cgttgtaggg cgttaacccc gctcgggcga taaacggttt tagcgccgca
     8701 aaaacgggcg caaatgaggc aggataaagc gggcagtcac aaaggtcttc tggtgtgcca
     8761 tcgcgatgca gcataccgag cagtggtttt tcaacgctac cactcaccac cattttggct
     8821 ttattacgaa acccttgttc cgggcctgac accggcgcgc accattcctc aaccggaaag
     8881 tcggcgagca gatttttaag atcggcggtt ttagcggaga gttgctctgg aatcggctgc
     8941 attatccact gacaggaacg acagcgaccc gcgtcgtaaa gtgcgcactg catacattga
     9001 ccttcacatc atcaggggcg acgattatac acattattgc aactggaaga accgccgact
     9061 ggtcgaggga acgaacagca gcatcaggat gagcatatcc ggcagcttct gcagcatcag
     9121 gctatggaag atttcacgtt ttgattcacc gggaatgctg aacagctccg gataaccgta
     9181 ccccagcgaa gccgcccaca agtaacttgc ggcggtgatt tgtgtcagca gatatagcca
     9241 gcgcgcccag cgacgccctt tcaccagtga aaacgcacac cagatctcaa tgaaaaccag
     9301 caccagactg cttaaaaaga ccagcgttaa actccaggtt tgtacgctgc gatgaatgaa
     9361 ctcgccaata ccgcgcacgc ccagcgtatt gaaaatcatc agcacgtcga ggccacggat
     9421 cataataatg gcgagcgccg ccacctgcac cagcgcaggc acattcaggc gagcatgaga
     9481 tgaagatgtt ttcttaaaaa atcccaacgt ttcgtcttcc atgaaaacaa tgccgcgaca
     9541 tgcgcggcat tatgtagcca ggttggcaaa ttttagtgtc ttcagccacg tcttgcacgc
     9601 tggatgtcgc gtatccgctg tttttctgcg cgagccatca gataccaggc gataaatccg
     9661 acaattccga ccgcgccgag gatcaatgtt gccagggcgt tgatttccgg attcaccccc
     9721 atccgcacgc tggaaaagac cagcatcggt aacgtggtgg ctcccggccc ggaaacaaag
     9781 ctggcgatca ccagatcatc aagcgacaaa gtaaaagcca gtaaccagcc agaaatgatc
     9841 gcgggcatga tcatcggtag cgtaatgacg aaaaacactt tcagcggcgt cgcaccgaga
     9901 tccatcgctg cttcttctat cgagcgatcc agttcccgca atcttgaaga aataacgacc
     9961 gccacataag ccgtacaaaa agtgacatgc gccagccaga tggtgagcat accgcggtcc
    10021 gcaggccagc caatggcatg agcaagcgcg acgaataata acaacagcga caagcccgtg
    10081 atgacatctg gcattaccag cggcgcggtg atcataaagg caaagccatt tgatccgcga
    10141 aacctgccaa agcgcaccag caccaccgcc gcaatagttc cgaggatcgc cgccgccgtc
    10201 gccgcacagg ccgcaattgt cagacttaaa ccaaccgcac tcatcatcgc gtcatcgcgc
    10261 aataactcac cataccagcg cgttgaccag ccggcccaca ccgtcaccag cttcgagctg
    10321 ttaaacgaat agataaccag catcagcatt ggcgcgtaga gaaaggtaaa gcccagcagc
    10381 aaaatcacaa tccgccaggg cgaacgaact accggtaaat tattcatccg tgttctccca
    10441 cgcttttttg ctggtgtttg tggaaccaca ttatcggcac aattagcagc agcaacatga
    10501 tgatcgctac cgccgaggcc accggccagt cgcggttatt gaaaaactct tgccatagca
    10561 cgcgcccgat catgatgctg tccgggccac cgagcagttc cgggatcaca aactcgccca
    10621 cagccgggat aaacaccagc atcgatccgg caataatccc acctttagtc agcggcacga
    10681 tcacagtaaa gaacgttttc agcggtcgtg caccgagatc cagcgctgct tccaccagcg
    10741 aataatcaat acgaatcaac gcggtataaa tcggcagtac cataaacggc acgtaagcgt
    10801 aaacaatgcc gatataaacg gccagattgg tatgcagaat ggtcagcggt tgatcgataa
    10861 cccccagcca cagcagaaaa ttattcagca caccgttgtt ttttaatatt cccatccagg
    10921 cataaacgcg gatcagaaac gaggtccacg acggcaggat caccagtagt aataaaatat
    10981 tacgggtcga aggcttactg tgcgccaccg cccacgccag cggatagccg atcagtaaac
    11041 agcaaaatgt cgaaatcgca gccacctgta gcgactggag ataagcatcg aaatagagcg
    11101 gatcgtcggt cagttgcaga aaattaccga gattaagagt gatggacagt tgcccgtcag
    11161 cccactccat cagttcggta taaggtggaa tagcgcgcgc catctccgcc aggcttattt
    11221 taaagacaat cagaaatggc agcagaaaca gcaagatcaa ccagatatat ggcaacgcaa
    11281 tgaccagttt gcgcccatgc ttcatttgca gctgcgacaa ccacagctta aatccgcccg
    11341 gcggtttcga ctgggcagca ggttcaagtg tactcatctt tgctccttaa accgtcagca
    11401 ccacacagct gtccacttcc cagcacaaac gcacttcgtc gccccaggtc ggtaaccctt
    11461 tacgatgacg atgggcgttt tgtagctggg cgctaatcat ctgcccactt ttcagacgaa
    11521 cgtgatacac cgaaagatcg ccgagatagg caatgtgtat cacctccccc accgcgaagt
    11581 tacaaccatt ggcgggcggc tcttcgcaaa gcatgatttt ttccgggcgc agcgccacat
    11641 gtaccggcac gttatcgacc accgaggcat ccgcgtcgac tttcagtgga tgcaccagcc
    11701 ccggcgaatc aagcaccagg ccatcttcct gacgctcttt gagtacgcct tcaaagacgt
    11761 ttaccgagcc aataaattcg gcgctatagc gggtagtcgg atgctcgtag atctcttccg
    11821 gttcgccaat ctggacaaat ttcccacgat tcataatggc gatgcgcccc gccatggtca
    11881 tcgcctcttc ctgatcgtgg gtgaccatca cacaagtcac accgacgcgc tccagaatat
    11941 ccaccacttc aagctgcatc cggtcacgca gctttttatc cagcgcgccc atcggctcat
    12001 cgagcagtaa tagtttcggg cgcttcgcaa ggcttcgggc cagggccaca cgttgtcgct
    12061 gaccaccgga aagctgatgc ggtttgcgtt tggcgaactc ctgcatatgc accaggccga
    12121 gcatctcatt gacccggctg gcaatttccg ctttcggtag tttgtcctgt ttcaggccaa
    12181 aagcgatgtt ctgttccacg gtcatatgcg gaaacagcgc gtaagactga aacatcatat
    12241 tgatggggcg caggtaaggc ggaacctgtg acaaatcgac gccatcaagc attatctgtc
    12301 cggcagaagg ttgttcgaaa cctgccagca tacgcagcag cgtggacttg ccacagccgg
    12361 atgcgcccag cagcgcgaag atttcacctt tgtagatggt caggctgaca tcatccaccg
    12421 catgttgacc atcgtaggat ttggtcaggt tgcggatttc taatagcggc gtcagcgcct
    12481 tacgggtttt cgcctgcggg cgagggatag cgtcattcac ggctgctctc cggcattgaa
    12541 tgtgtgcaag cgcaccataa tggtgcgaat tgccggcggg tgtggtgcgc ccctccggca
    12601 tctacgactg cggattattt tccgctcttc actttggtcc acgcgcgggt gcgcacacgg
    12661 tcgattttcg gatcctgcac tttcagagtg aacagcttcg cacgaacatc cgcaggcgga
    12721 taaatacctg ggttctcacg gacttccgca ctcaccagcg gcgtggctgc tttattggcg
    12781 ttggcataga acacatggtc ggaaatatgc gctactacat ccgggcgcag caggtaattc
    12841 aggaactgat aggcttcgtc tttgtttttg gcatccgcag gcatggcgaa tacatcaaag
    12901 aacgccatcg ccccttcttt tggaatcgag aacgagacat tcacgccatt cttcgcttcc
    12961 ttcgcgcggt ttgacgcctg ccagacatca cctgcccagc cgatagcgac gcaaatatcg
    13021 ccgtttgcca ggtcgttaat gtattgagat gaatggaaat aacgaatgtt cgggcgcagc
    13081 tttaacagca gatctgttgc cggtccggtg taatcatccg ctttagtgct gttgggatct
    13141 ttgccgagat aattcaacac ggtagcaaaa acttcttctg gcgcatccag gaaagagaca
    13201 ccgcagcttt tcagtttttc cagattttca ggtttgagga tcaagtccca gctatcgacg
    13261 ggcgcgtttt cgcccagcac cgctttaact ttatcaacgt tatagccaat cccggtcgtc
    13321 gcccacatat agggcatagc aaatttattg tcgggatcgt gtttggcgac cagcttcagc
    13381 agttccgggt cgagattctt ccactccggc aatttgcttt tgtccagcgg ctggaaaact
    13441 cccgcagtca actggcgctc cagaaagctg gcagatggaa ccaccagatc aaagccggta
    13501 ctcccggcca ttaatttgcc ttccagtact tcgttagagt cgaaaacatc gtagacgact
    13561 ttaataccgg tttctttttc aaaattggcc accgtgtccg gggcgatata atcagaccag
    13621 ttataaatgt ggagtgtttt ttgttcagcc gcgagcgtgc cgacagagac ggccatcaga
    13681 gcacccgcaa ccagacccga tagccatttt ttatttaagg cggtcatatc tctttccttc
    13741 tgaaagttcg ttaacaaacg aacaaaagtt gtcacactga aagatatgca ataaacgtgc
    13801 atatttttta tcggcgcggt gtaagaaaag agaactttct cccggccagc actgctcgcc
    13861 atataaaagc atcgcaagaa taactttagc cagggtttga gactatagct cggattaaaa
    13921 aacggtattt aacaaatttt tatgcatatt tgctctatgt gataaagcca aatcgacaca
    13981 agagaagtga aataatcttt aagaaaaggt taaaaacagc agataatttt gcagcgcgca
    14041 gccactgcac cagcgactgc gtgctcgaaa ggagttatca gtggaggaaa tagttttcgg
    14101 taacgttgtt ttgcccttca tcatcagtcg gtaacagcag ttgatgggca ttagcttcaa
    14161 gaatgaccat cgaaatctgc tcttcgctct gacgcacgaa ccatgcaaac tgctcatagg
    14221 ttacgccctg cataacggat aaagactggc aaaccaccag ctttggcaga ttatcatcct
    14281 gcatatcaag aaatgctttc acggtcagcg aactggcatt gatggcagat aaatccgccg
    14341 ccagcggcaa tacggctgaa ggtcggactt ccgccatggc agaaaacagg atcgtgttat
    14401 cgatcagatc gattttggca tcaaagacac cgtcgaaatt ctgcatatgg ggcagatgca
    14461 gagcctgaca gttatcacat tcaaaaaaac tcatccccag gtcatcgagc cattgacgca
    14521 gcgtatccag accaggaacg accagcgatg tcataatttt gtacaacctc tttcgataaa
    14581 aagaccggca cagcttacgc aaaaagcgca ggcaaaacca tgatcagtaa tgtgattgcg
    14641 actaaccacc cgttttcagg caatattctg tcgtagcgtg gcgttcgatc cagcggatca
    14701 ttttacccgc gatgtcgata ccggtggttt tttctattcc ttccagcccc ggcgacgcat
    14761 tcacctccat caccaacggc ccgcgattag cacgcagaat atccacacca gcaacgtcca
    14821 gcgccatcgt tcgcgcggct tttatcgcga tttcacgctc ctgtggtgtg atactggcga
    14881 cgcttgccgc gccgccacga tgcaaattgg aacgaaaatc gccctctttc gcccgccgtt
    14941 caatcgcagc gaccacttca tcgccaacaa ccagacagcg gatatcgcac ccttgcgcct
    15001 ctttgatata ttcctgcacc agaatatgcg cgttcagacc gcggaaagcg tcaatcacgc
    15061 tttccgccgc ctgacgcgtc tccgccagca cgacgccaat tccctgcgtg ccttcaacca
    15121 acttgaccac cagcggcgca ccaccgacca tgtcgattaa atcgctggta tcatccggcg
    15181 aatgcgcaat gcccgtgaca ggcaggtcga tgccctgacg cgccagcagt tgcatggaac
    15241 gcaatttgtc acgcgcccgg gcaatggcga ccgactcatt gagcggatag ctccccagca
    15301 tctcgaactg gcgcagtgcc gccgtcccat aaaaggtaat ggcggtgcca atacgcggga
    15361 tcactgcgtc aaaatggggt aacttgcggc ctttgtagtg aatagaagac gccgcaggat
    15421 ttatgttcat gtagcaagaa agcggatcaa gaatttcaac caggtgaccg cgctgtatag
    15481 cggcttcacg cagccgctta cacgaataga gcgttccatc ccgggacaat atggcaattt
    15541 tcaccctgca cctctctgtc agacctggtc aaaagcccgc gtatcataca tcgacgtggc
    15601 ggttttagcg cgtcgcccaa ccctgtttgt gcaaataatc cagaataaat gggcggcttt
    15661 ctttaatgat tgttcggcgg atatgatcgc tccaggtatc ccggcgatta ttgctgccac
    15721 gggtgaggta atattccgcc agttgctcgt catactgcgc cagtgcgcct ttatccagcg
    15781 gttgatagct gttttcatgc accaaaatgg aggccggtaa acgcggctta agatccggat
    15841 tatccgcagg ccagccaagg cacagcccaa acagcggcag aacatgctgc ggtaatttaa
    15901 gcagtttcgt caccgcttca atattattgc gcaggccgcc gatatatacc ctgcccaatc
    15961 ccagcgattc cgctgcgatt aatgcattct gcgccatcat tgccgtatca acgacaccga
    16021 gcaacagttg ttccgccagg ccgagctgag catccggaca gatctgtaaa tggcggttaa
    16081 agtcggcaca gaacacccag aactccgccg cttgcgctac gtgtttttgc ccgccggtca
    16141 gcgtcaccag ttcttcacgt aacgcattgt cggtaatgcg aataatgcta ctgcactgca
    16201 aaaaactgga actggacgtc gcacgggcgc tgttaataat cgcctcacgc tgcgcttcgg
    16261 aaatgggttc atcagtgaaa tggcgaatgg agcgatggcc acaaataagt tcaatggttg
    16321 gcgtcattat ctttttctct ttctgaacgt gaatattgcg gtggacggtt catcagctgt
    16381 ggggcaagac gttttgccac ctgaagaata accaccaccg cagcgggaag catgagcaaa
    16441 acaccgagaa aaatcatcag aatctgcact tctggccgag aaaatggctc aggcagcgac
    16501 agggagtcgc ttaccgacag cagcgccacc gccagtagca tcattccgat aaattccagt
    16561 atcaacacgc ctttaggcaa tttaccgatc gcgcgcatac gcttccctct gcaaagtgag
    16621 ccttcagtct aaaacttttc actgtattgt gtttaacagt tatagctttt agcaattaat
    16681 gcaacaggtt aaacctactt tcagcgaata cattttagcg tgatcattac aggcataaat
    16741 ctatgaggag agaaataatg caaaccgtta tttttggtcg ttcgggttgc ccttactgtg
    16801 tgcgtgcaaa agatctggct gagaaattga gcaatgaacg cgatgatttt cagtatcagt
    16861 atgtagatat tcgtgcggaa gggatcacta aagaagatct acaacaaaag gcaggtaaac
    16921 ccgtagaaac cgtgccgcag atttttgtcg atcagcaaca tatcggcggc tataccgatt
    16981 ttgctgcatg ggtgaaagaa aatctggacg cctgatcgtc tgacaagccc tcgcgttgag
    17041 ggctttactg attttttctg tgctgtggtt taaacaaact actgataaat aagaaacaca
    17101 gtgcccccag cgcacaccag aacaccgcgc ttagtaacca tgccagctct tgccagaatg
    17161 agcgcgtcgg tgaaaaaaac agccgcataa tgagcatcga acagggtgcc gccagcattg
    17221 cgccaaacag aggtttcagg acttctctac gctgtgaaaa gaagctggcg actgctccag
    17281 gaagaatgaa aaatagcaag ccgatttcag gatgcccggc agcccgaaaa gcgcctttca
    17341 tgtgcgtcgc cagaaaaagg cacaccacaa tgaagaggac aaaacagcag attgcccccg
    17401 cccaacgttg tttatgtttc actcgttcct cctgacactg cgtctatcga acacattttt
    17461 cgccagtgtg gcgttcagta agataaagcc gcttcgcatt ccatgctaat ataggccaac
    17521 gcaattcata tagccgttga tacctaatgt gattacacta gtaaaatata ttgttacttt
    17581 actatcgttt aggtgcgctg aatgaatctg cgccctgaat tctggtaaaa aacattatcg
    17641 taaattacca tttctttcaa cagcttacta gtaaacaaga agttagcctc cgtgaatata
    17701 aacgtcgccg aattgttaaa tgggaattac attctgttat tatttgtggt cctcgcgctt
    17761 gggctatgtc tcggaaagtt acgacttggt tcgatccaac tgggtaattc cattggcgtt
    17821 ttagtcgtat cgctgttatt aggccaacaa catttcagca ttaacaccga tgcgcttaat
    17881 cttggcttta tgctgtttat tttctgcgtc ggggtcgaag ccggaccgaa ctttttttcc
    17941 attttttttc gcgatgggaa aaattaccta atgttagcac tggtgatggt tggcagtgcg
    18001 ctggtgatcg ccttagggtt aggtaagctg tttggctggg atattggcct gacggccggt
    18061 atgttagcag gctctatgac gtcgacaccg gttctggtcg gtgctggcga tacactgcgt
    18121 cattccggca tggaaagcag gcagctctca ctggcactgg ataatctgag cctcgggtat
    18181 gccttaacct atttaatcgg tctggtgagt ttgattgttg gtgcgcgtta cttgccgaaa
    18241 ttgcagcatc aggacttaca gaccagcgcc cagcaaatcg cccgcgaacg tggcctggac
    18301 actgatgcca accgtaaggt ttatttaccg gtgatccgcg cctatcgcgt cggcccggaa
    18361 ctggtggcct ggaccgacgg caaaaatctg cgtgaactgg gtatttatcg acaaaccggc
    18421 tgctacattg aacgtattcg acgtaacggg attctggcaa atccagacgg tgatgccgtg
    18481 ctacaaatgg gcgatgaaat agcgttggta ggctatcccg acgcccatgc ccgactcgat
    18541 cccagcttcc gtaacggtaa agaagttttc gatcgtgacc ttctcgacat gcgtatcgtc
    18601 actgaagaag tggtcgttaa aaaccataac gctgtaggta aacgtctcgc acaactgaag
    18661 ttgaccgatc acggttgctt ccttaaccgc gtcattcgta gccagattga gatgccgata
    18721 gatgacaacg tcgtgcttaa caaaggtgac gttttacaag tcagcggcga tgcccgccgc
    18781 gtaaaaacca tcgccgatcg catcggcttt atctcgattc acagccaggt cactgacctg
    18841 ctggcattct gcgccttctt tgttattggg ctgatgatcg ggatgatcac cttccagttc
    18901 agcacattca gtttcggcat ggggaacgct gccgggttgt tattcgccgg aattatgctg
    18961 ggctttatgc gtgctaacca cccgaccttc ggttacattc cgcagggtgc attaagcatg
    19021 gtgaaagagt tcggcttgat ggtgtttatg gcaggcgttg gtctgagcgc cggtagcggt
    19081 attaataacg gcctgggcgc gattggcggt cagatgttga ttgccggatt gattgtcagt
    19141 ctggtgcccg tggttatctg tttcttgttc ggtgcttatg tattgcgaat gaaccgcgcg
    19201 ctgttgttcg gcgcaatgat gggcgcacgt acctgcgcgc cggcaatgga gatcatcagt
    19261 gatacagctc gcagtaacat cccggcgctg ggctatgcgg gcacctatgc aatcgccaac
    19321 gtcctgctga cgctggcagg gacaatcatc gtcatggtat ggccaggatt aggataaaac
    19381 tgaagttgcc ctgaaaatga aatttttttg cacaaccgca gaacttttcc gcagggcatc
    19441 agtcttaatt agtgccactg cttttctttg atgtccccat tttgtggagc ccatcaaccc
    19501 cgccatttcg gttcaaggtt gatgggtttt ttgttatcta aaacttatct actaccctgc
    19561 aaccctctca accatcctca aaatctcctc gcgcgatagc ggcttacggt cggtgacaaa
    19621 atgcagcgtc atcccctcaa taaacgcatc aagcgcgcgg gcggttccgg gttcaaacca
    19681 ttgttcgagc gtttgctgac tgcgctgcat ccagttttgc attaccgttt ttaatagcgg
    19741 ttttcggcta gccagcgcgt agagctggta catcagctcc atgttatccg gcgttgcaac
    19801 ctgtgagctg tagatcatat cggtgatagc ctggcatgcg cccggagcat cactaacatc
    19861 gctaaaaaat gcctgatatt gccgggacat gatctcagta aaactgctga acgcctccag
    19921 taacaactca tcaattcctg aaaaatagta ggtcatcgat cccaacggta ccccggcaag
    19981 ggtagcaatt ttgcggtgcg taacagcatg tattccgtaa agtttcaccg cctccagcgt
    20041 ggcctggata attttttctc gccgttgcgg atcgttagcg cgacgcatgt catttcctct
    20101 ctctgcaatt gtgtacaaat gtacacaacc ttgctaatgt tgtcttccct cttcttattt
    20161 tgacgtgatc tatgaccgta aattcttcac gtaatgcatt gaaacgccga acctgggcgc
    20221 tgtttatgtt cttctttttg ccaggcctgt taatggcgtc ctgggcaacc cgtacgcctg
    20281 ctatccgcga tattctctct gtctcgatcg ctgaaatggg cggtgttctc tttggtctgt
    20341 cgatcggttc gatgagcggt attctctgct cggcgtggtt agtgaaacgc tttgggacac
    20401 gtaatgtcat cctggtcacg atgtcctgcg cattgatcgg gatgatgata ttaagtctgg
    20461 cactctggct gacatcgccc ctgctctttg ccgttggtct cggcgtcttt ggggcaagtt
    20521 ttggttctgc ggaagtggcg ataaacgttg aaggtgctgc cgttgagcga gaaatgaata
    20581 agacggtttt gccgatgatg cacggttttt atagcctggg cacgctggca ggcgcaggtg
    20641 tcgggatggc actgacggcc tttggcgttc cggcaacggt gcacatttta ttggcggcgc
    20701 tggtaggtat cgcacctatt tatatcgcca ttcaggcaat ccctgacggt acgggcaaaa
    20761 atgctgccga tggcacccag catggcgaaa aaggcgtacc tttttatcgc gatatccagt
    20821 tgctgctgat aggtgttgtg gtgctggcga tggcctttgc cgaaggttct gccaacgact
    20881 ggttaccctt attaatggtt gacggtcacg gttttagccc tacttccggc tcgctgattt
    20941 atgccggttt taccctgggg atgaccgttg gacgcttcac cggcggttgg ttcatcgacc
    21001 gttacagtcg cgttgccgtg gttcgggcca gtgcactaat gggggcgttg ggtattgggc
    21061 tgattatttt tgtcgatagc gcctgggtcg ctggggtgtc tgttgtactc tggggactgg
    21121 gtgcctcgct gggcttcccg ctgaccattt ctgccgccag cgataccggc cccgatgcac
    21181 caacccgcgt cagtgtggta gcaacgaccg gttatctggc tttcctcgtc gggccgccgc
    21241 tgctgggcta tctcggcgaa cattatggat tacgtagtgc aatgctggtt gtactggcgc
    21301 tggttattct cgcggctatt gtcgcgaaag ccgtcgccaa acccgatacc aaaacgcaga
    21361 cggcgatgga gaatagttga tgagcattaa attaattgcg gtagacatgg atggtacttt
    21421 cttaagcgat caaaaaacct ataaccgtga gcggtttatg gctcagtatc agcaaatgaa
    21481 agcacaagga attcgctttg tagtcgccag cgggaatcaa tattatcagt tgatctcttt
    21541 cttccctgaa attgctaatg aaattgcctt tgtggctgaa aacggcggct gggtagtgag
    21601 cgaaggcaaa gatgttttta atggcgagct atcgaaggat gcgtttgcta ctgtcgtgga
    21661 acatttgctg acgcgcccgg aagtggaaat tattgcctgc ggaaaaaata gtgcctatac
    21721 actcaaaaaa tatgacgatg ccatgaaaac ggtggcggaa atgtattatc accgtctgga
    21781 atacgtcgat aactttgaca acttagagga tatcttcttt aagtttggcc tgaatctttc
    21841 cgatgaactg attccacaag tacaaaaagc attacatgag gccatcggcg atattatggt
    21901 gtcggtccac accggcaacg gcagcatcga tctgattatc cccggcgtac ataaagccaa
    21961 tggccttcgc caactgcaga aattatgggg aatagacgac agcgaagtgg tggtctttgg
    22021 cgatggcggt aacgatattg agatgctgcg tcaggcaggc tttagttttg caatggaaaa
    22081 tgccggtagc gcggtcgtcg cagcggcaaa ataccgcgca ggctccaata accgtgaagg
    22141 cgtactggat gtgatcgata aagttcttaa acacgaagcg ccatttgacc aataaaaccg
    22201 gcagcacgcc cggcaacaca atgcctgaat gaaggctgca taattcgcgg aaattaaccc
    22261 gctgcattat ttcaggcgaa atgattatga aaaattgtct actgttgggc gcgcttttaa
    22321 tgggctttac tggtgtggcg atggcgcaaa gtgtcaccgt cgatgtgccg agtggataca
    22381 aagtggttgt ggttcctgat tcagtcagcg ttccacaagc ggtcagcgtc gcgactgtgc
    22441 cgcaaaccgt ctatgtggct cctgcgccag ctccggctta ccgcccgcat ccttatgttc
    22501 gccatcttgc cagcgtaggt gaagggatgg ttatcgaaca ccagattgac gaccatcacc
    22561 attaattcga gaatgcctga tcgcacaaag cagtcaggca tttttttacc cttcgtgaga
    22621 atttcccatc tgtttatctt ttaaaaagat aaccatcagc gacagccaca aaattccgtt
    22681 gacaaggttg aagagattaa acagtccgtt gcccccgttc agccaggcat gtttgctgat
    22741 ttcaatacca acggtaaaga tcagcatttg cagcattccc atcgcggcag aaaccgtacc
    22801 tttactcata tcgctggcaa acagggttaa tcgcaccagt cccgcattcg ccagaccaat
    22861 accgaaagca taaatactta acccggcagt catccataaa tacgcgtgcg atgagataac
    22921 cgttgccgca gcagcgacca atagaccaat cataatcggc cagccgccca taataatcag
    22981 cgaacgtacg gtgcggcgcg aggtcagacg cgctaacagc aagttacccg caattaacgc
    23041 cccgaaaata ggcacttgca gcaagccata ttcatagctg ctcaactgct cgccggtaat
    23101 gatgataatc ggcgactggg cgatccacgc cagcaacggc agactaacga atcccagcgc
    23161 cagcgccccc gccacaaagc ggccgttctt cagcaccagc ttatagtcac gaccgagttc
    23221 tttcagtgac agtttctcgc ctatacgcgt ggcggtttca ggcatggctc gttgcagacc
    23281 gaaaaaggag atcgctgcca atgcggcaaa caaaacaaac atcccctccc agggcagcac
    23341 atggatccac gccgcgccca ccagcggacc aagtagcgga gcaatcagcg ccacgttcgc
    23401 catcagcgcg gtgatcttga tacaaaccgc ctcttcgaag gattcctgaa ttgcggcgta
    23461 tcccacagcg ccaatgaaac agaggcttat gccctgcaag aagcgcaaca gggtgaattg
    23521 ttcaatgttt tgcgccagca atattgccag acaggtgacg ataaaccaca ccactcccgc
    23581 cagcatcacc ggacggcgac caatacgatc cgacagcggc cccagcagcc attgtaaaaa
    23641 catcccgccc gccagatacg cggtcatcga agtaggaacc caatcaatgc ccgcctgata
    23701 ttgttccacc acggccaaca taccgggttg aatcatatcg ttgccgatat aggttgaaaa
    23761 ttcgtaaagc accagacaga gagggaaaag taacgcctga cgtccaagcc tggcaccgga
    23821 agctaattta ttttgcatgc aatttcttcg ccaataataa tcgcgcagag tttaataaaa
    23881 gcgcagctaa cgagaaagcg aattttgtag ctgaaaccac ggttaagcac attcttacat
    23941 tattacgagt atagctacgc tttctttaag ttttatttaa cctatgcccg ttacaatcac
    24001 ccaccgtaaa caggccgctt gagggaaata agacgatgcc gctttaccca gtttaacctg
    24061 cactttattc tcaacgactt gcctgtattg gctccctttt aatcactttg cgtcgggaag
    24121 ttatgctgga aaatttgaat ctctctctat tctctcttat taacgcgacg ccagactcgg
    24181 ctccgtggat gatctcgttg gcgattttta ttgctaaaga tttgattacc gtggtgccgt
    24241 tgctggccgt ggtactttgg ttgtgggggc ttacagcaca acggcaactg gtgataaaaa
    24301 tcgctatcgc gctggcggtc agcctgtttg tgtcctggac gatgggacat ctttttccgc
    24361 acgaccgacc ctttgtcgaa aatatcggct ataacttcct gcatcatgcg gcggatgact
    24421 cattcccaag cgatcacggt acggtgattt tcacctttgc actggcattt ttatgctggc
    24481 atcgcctgtg gtccggctca cttttaatgg tgctggccgt cgtcattgcc tggtcgcgcg
    24541 tttatcttgg cgtccactgg ccgctggata tgctcggtgg attgctggca ggtatgattg
    24601 gctgccttag tgcccagatt atctggcaag cgatggggca taaactctat caacgtctgc
    24661 aatcgtggta tcgcgtctgt tttgcattac cgatccgcaa aggctgggtg cgtgactgat
    24721 ctctgctaaa aagtgtagta ttgagcggct cgcttcaata actattcaga gggattatgg
    24781 aaacacgtcg cgaagagcgt atcgggcagc tgctgcaaga attaaaacgc agcgataagt
    24841 tacatcttaa agacgccgcc gccctgcttg gggtttcgga gatgacgatt cgtcgcgatc
    24901 tgaacaacca cagtgcgccc gtcgttttgc tcggcggcta tattgttctg gaaccgcgca
    24961 gtgccagcca ttacctgtta agcgatcaaa aatcccgcct ggtggaagaa aaacgccggg
    25021 cggcaaaact ggctgcgacg ctggtagaac ccgatcagac cctctttttt gactgtggca
    25081 ccaccacgcc gtggattatt gaagcgattg ataatgaaat cccttttacc gccgtttgtt
    25141 attcgctaaa tacctttctg gcgctgaaag agaaacccca ttgccgcgcg tttctttgcg
    25201 gtggtgaatt tcacgccagc aacgccattt tcaaacccat cgattttcag caaacgctga
    25261 ataatttttg cccggatatc gctttttatt ctgcggcggg cgtgcatgtc agtaaaggcg
    25321 ctacctgttt taatcttgaa gagttgccgg taaaacactg ggccatgtcg atggcgcaaa
    25381 agcatgtgct ggttgtcgac cacagtaaat ttggcaaggt gcgtccggcg cgcatgggtg
    25441 acctgaaacg ctttgatatt gtggtgagcg attgttgccc ggaagatgag tatgtgaagt
    25501 acgcgcagac gcagcgcatt aagttgatgt attaatgacg tataaccgga tgacgtttcg
    25561 cgccatccgg ttatcagaag attaagagaa ccagctgccg aaccactgat ggaatttcat
    25621 catcacgaaa tcccacaccc gaccaaagaa tccgccctct tccacatttt ccatcacgat
    25681 cagcggacgc tgctcaatgg atttaccgtt aagctggaaa tcaatggtcc cgacaacctg
    25741 accttttttc agcggtgcgg taagctgcgg ttccgttaac gtataactcg ctttcaggtt
    25801 tttcagctgc ccacgcggta tggtcactga gcccgcttca cctgccccga gattcacttc
    25861 gctcttatca ccaaaccaga cgcgctgagt cacaaaggtg gcatcaggtt taattggcgt
    25921 cacggtttca aagaagcgga aaccccaggt caataatttc tcagactcat taaaacggat
    25981 acggtcggtt ttcgccccca acactacgga gattaaacgc atatcgccct gggtagccga
    26041 agcaaccaga ttatatcccg cgcctgccgt ggttcctgtc ttcatgccat caacattcag
    26101 attgctgctc cacagcagac ggttacggtt aggctgacga attttgttga aggtgaactc
    26161 tttctcttta tgaatggcgt actcttccgg cacatcgtgg atcaatgctt tacccagcaa
    26221 tgccatatcg cgcgcggtgc tgaactgccc cggcgcatcc aggccgtgca ccgtctggaa
    26281 ggtagtgttg gtcagaccca gttttttggc ataaccattc atcagaccaa taaatgactc
    26341 ctggctcccg gcaacgtaat cagccagcgc aatacaggcg tcattaccgg actggataat
    26401 cacacctttg ttcaagtctg ccaccgaaac ctgatcgccc ggtttgagga acattaccga
    26461 tgaaccacgc agtgccggat ttcccgtcgc ccaggcatct ttaccgaccg tcaccatatc
    26521 ggtgagttta atcttatcgg ccttaagcgc ctgcccaacc acatagctgg tcatgatttt
    26581 agtcaggctc gcgggatcca gtttctcatc cgcattgcct tctgccagca ctttaccgct
    26641 ggcgtaatcc attaaaatcc atgcacgcgc atccacgctc ggcgcttcaa cggtttgttc
    26701 cgccgcgaat gccgttgggg caaaaaggaa taaaaatgca gaacccgctg caagaccacg
    26761 aaggagagag gagtattgcg tcataaatgc cacccgagta tccattcaaa aaaaatacgt
    26821 tatatcgccg tatgataagt ttggtgatta ataacgcaca cacaaactta aagaaaccgt
    26881 aagttggtaa agtttttaaa gtttatgcaa tatcctgccg cttcgctgct tctggtgtca
    26941 tttttttgcc agctgttgct taaaagttaa ctttacttca ccatcggagt cctgttcagc
    27001 ctgtggctgc ctgtcggaaa aggggtgagt atgattacgc tgtggggtcg gaataattca
    27061 actaacgtaa aaaaagtatt gctgacgctc gaagaactgg aactacctta tgagcaaatt
    27121 ctcgcgggcc gtgagtttgg gataaatcac gatgctgatt ttctggcgat gaaccctaac
    27181 gggctggtgc cgttgttgcg tgacgacgaa agtgatctca ttctttggga atcaaacgcc
    27241 attgtccgct atctggcggc acagtacggg caaaaacgcc tgtggatcga ctcaccggca
    27301 cgtcgtgcgg aagcggaaaa atggatggac tgggcaaacc agacgctcag taatgctcat
    27361 cgcgggatcc tgatgggatt agtcagaaca ccaccggaag agcgcgatca ggccgccatt
    27421 gatgccagtt gcaaagagtg cgacgccctg tttgccctgc tcgatgcgga actggcaaaa
    27481 gtaaaatggt tctctggcga cgagtttggt gtgggcgata tcgctatcgc accgttcatc
    27541 tacaatttgt ttaacgttgg cctgacctgg acaccgcgtc caaatctgca acgctggtat
    27601 cagcaactca ctgaacgccc cgcagtgcgc aaagtggtga tgattcccgt tagctaattg
    27661 cgtgggctaa ctttaagtaa ttccccactg gactcgtcgg tgagaacgta taaataaccg
    27721 tcgggtccag tgcgaacatc acgaattcgc tgccctctgt ccgttaaaat acggccatct
    27781 tctgtcactt tgtcgccgtt gacgctcatc acaatgacat ctttatcttt cagcgcgcca
    27841 ataaataatt tttgctgcca ctgggggaat ttatcgctgt tatagaaggc catgccgctc
    27901 acagcgggcg aatctttcca gtaaaaaaca ggttgctcgg tcccggcgac gatctcccct
    27961 ttcgcttccg gtatcttaaa gcctgaatag ttgattcccc aggttgccag cggccagccg
    28021 tagtttttgc ctttttgcgg gatattaatt tcatcaccac cgcgcgggcc atgttcattc
    28081 agccacagtg cattactcca cggattcatc gccattcctt gcggattacg aatgccataa
    28141 gaccagatct cggcgcgcgc accggattcc tttataaaag gattatcatc cgggatttcg
    28201 ccctggtcgg tcagacgcac cagtttgccc tgtaatttat ccagatcctg cgccgtcggg
    28261 cgctgattgt tttcgcccag agcaataaaa agataacctt taccgtcgaa taccagccgc
    28321 ccgccaaaat ggttgccggt agacagtttt ggcatctggc gaaagacggt gcggaagtcg
    28381 gtcacttttg agagatcatc acttaagcgg ccataaccca cagcagttcc ggctttgcca
    28441 tcatcgccaa cttcggaata acttaaccag atgcggcgag actgagcaaa atcaggcgct
    28501 aaaaccacgt ccagcaggcc gccctgcccg tgcgcccaaa cgtccggaac tccggaaagc
    28561 ggcgcagata atccttttcc tgcttgccag tgacgcaact cgccgccgcg cagagtgatt
    28621 aacataccgt gattatcggg taaaaaggcc agtgcccagg gatggtcgag tttgtcttgc
    28681 agtacttcga catttaccgt tgcaggagcc gcccagagag cggaagaaag acaaataagg
    28741 ggcacaagga aaaaggattg tcgatgcata acgcctccgg attgactctg gcttaaagcg
    28801 tagtcagtgg aggagataac aaattcattt ttacaaaaac ttaaacatga agggggagac
    28861 gctttctccc ccttagtttt caggccttct caagcatggc gtgcttctgc aggctctgga
    28921 tactcagcgt taagctcatc agacaatttt caagcttatc ggcgttgacg gtaataacag
    28981 tcgggcaatc atggtgccca ctcatcaaac atactgcggc tgtcgctaat gcttcttcag
    29041 catgatgaag agcactccac tcttcctgat ccagatgaag attcaaccgc agcgatttat
    29101 cgtgcagttc gcgattcagt ttaaaaaagt tatctcgtag atgattgctt tcgctgacgg
    29161 acatgtatcc ttttgccttc ctcagttgca cgtatgcggc gaggtcaacg cgtgcgtcga
    29221 tcaaccggtt cagcagatcg attcgctgtc tgtcaacgaa catacttcga tcctcctctt
    29281 cccagccttg ttgcaattaa atagtatggc tattttttga gcaaaatgct gtccaggatc
    29341 aattcttcac gccgaattaa caaaatttac atttccttcg cctccgccag cgaatgagat
    29401 tgcgatacaa attttatcca gaactctgta gaatccctgc cctgaccttt cctgtaactg
    29461 aatatttttt aagctatgag caaagtaact ccccagccga aaatcggctt tgtttccctt
    29521 ggctgtccga aaaaccttgt tgattcagag cgtattctca ccgaactccg cactgaaggt
    29581 tatgacgtgg taccgagcta tgacgatgcg gacatggtga tcgtcaacac ctgcggcttt
    29641 attgacagcg cggtacaaga atcactggaa gccattggtg aagcgttgaa tgaaaacggc
    29701 aaggttattg tgaccggttg tctgggggca aaagaagatc agatccgcga agtccacccg
    29761 aaagtgctgg aaatcaccgg gcctcatagc tatgagcagg ttctggagca cgttcatcac
    29821 tacgtgccaa aaccgaaaca caacccattc ctgagcctgg tgccagaaca aggtgtgaaa
    29881 ctgacgccgc gtcattatgc ctatctgaaa atttctgaag gctgtaatca ccgctgcacc
    29941 ttctgcatta ttccgtctat gcgcggcgac ctggtgagcc gtccgattgg cgaagtgtta
    30001 agtgaagcga aacgtctggt agatgcgggc gttaaagaga ttctggtgat ctcgcaggat
    30061 acttccgcct atggcgttga tgttaaacat cgtactggct tccacaacgg cgagccggta
    30121 aaaaccagca tggtcagcct gtgcgaacag ttatcgaaac tggggatctg gacacgtctg
    30181 cactacgttt acccttatcc gcatgtggac gacgtcatcc cactgatggc agaaggcaaa
    30241 atcctgccgt atctggacat tccgttgcag cacgccagcc cgcgcattct caaactgatg
    30301 aagcgtccgg gttctgtaga tcgccaactg gcgcgcatca aacagtggcg cgaaatctgc
    30361 ccggaactga ccctacgctc aacctttatt gtcggcttcc ctggcgagac agaagaagat
    30421 ttccagatgc tactcgactt cctgaaagaa gcgcgtctgg atcgcgttgg ctgctttaaa
    30481 tacagcccgg ttgaaggtgc agacgccaat gccctgcctg accaggttcc ggaagaagtt
    30541 aaagaagaac gctggaaccg tttcatgcag ctgcagcagc agatttccgc cgagcgcctg
    30601 caagagaaag tgggccgtga aattctggtg attatcgacg aagtggacga agaaggcgcg
    30661 attggtcgca gcatggcaga tgcaccggaa atcgacggcg cggtttatct caatggtgaa
    30721 accaacgtta agccgggtga tatcctgcgt gtgaaagtcg agcacgccga tgagtacgat
    30781 ttgtggggta gccgggttta attaattcag gccgggcaaa atcatttgtc cggcctgcga
    30841 ataatgatta ctgccagcta atctgtgccc tgccgttttt cttactctta tacagccgct
    30901 catccgccag cattttcaag cgttcgacgg taggacattc atttgaatgt gctacaccga
    30961 tactggtact taaattaatg cttcccacct ggaaatgaac gatttctttt agaatcgata
    31021 gcaactcttc cagcgttcca cccgtataaa tcaccgcaaa ttcgtcaccg ccgaagcggt
    31081 agactttacc tttatctacc gggatctgtg atttaaggat tttcaccact ttcatcaaca
    31141 cttcatcgcc cagcaaatga ccgaaggtgt cgttaatgtt tttgaattta tcgacgtcaa
    31201 acaggcacaa ataaccgcct ttttccggca gcgcttttaa atcttcgtca aaggattttc
    31261 tgcccattgc tttggtcagg tcgtccagga acgccgagtt atacatactg tagagttttt
    31321 tgacatcggc agccgaaaag aaaagcccgc catccagtac gcgttcaaaa tggttattaa
    31381 tgatggcttc tttctccaca ataccacgat taatcactct gcgtaccaga tagaggcaac
    31441 tggcacccga tatcactgcc accaatgcgg caaagaaaat aatcaatgta caaacccgca
    31501 aataaacatc ttttttatac gcaaatacat acaatccggt cggcaaatag gcgaagtgct
    31561 ccatcgcttc cgaaacggtg aagatggcgt ttttagcatt atattcatca ccggtcaccg
    31621 gtttaccgtt cttaaataga gagaacatca ggttctcgct gtccatcgcc agcgattttg
    31681 acagtaaaga aaaacgctcc agaccaagca aaaatatcag actacgattg tgagttaccg
    31741 gatagaggta atagacgaag gttttaccgt caaaagagat aaaccctgta tttttgacat
    31801 gtcgatactt cacaacctgc ataatatctg cacaataatt tttctcgaac tcctttacct
    31861 gaatacattc gtcactggaa atcagataag gaccgacatc gtacaaataa gagggggaaa
    31921 ccgagtcggc gtaagctgtg cgcaaaccaa ccaacagctg ttcctccgtg ggatttagcg
    31981 tgttgataag atcaattgcc acgctacgcc gatattcagc aatatttgcc accgcaaaag
    32041 cagtatcaat aacggactgt ttcaggctat acacccgttc ctttaccatt tgagtgtaga
    32101 tcccgcaggc aactgctgaa atcatgataa aaatcagcag actgactgta agtacgaact
    32161 tattgattct ggacatacgt aaactactct tttactaatt ttccactttt atcccaggcg
    32221 gagaatggca tgggtttctg gtacagatac ccctgagcct gaacacatcc taatttgatt
    32281 aattcgcgcg caacgtcttc gctctctacg ccttccgcaa tcaccgggat ccggttatag
    32341 cgtgccaggt cgaaaataat gcgcacaatt tttcccgcag taccgaaaat atcgccggtg
    32401 aattgcgagt ccacctttat gctgtctgga ttaatttcat aaaaacgttt caggtttgac
    32461 aaaccggtgc caaagtcatc aatcgatatc cgtacccctt gtttacgcag ttgttcaata
    32521 ttgagataaa aatgttcatt aattcgctcg atcacggttt cagtgatctc aacacagagg
    32581 ctgttcgcct tcaggccatt ttctttcatg atggtggtaa aacgctcatg aaagtgtggt
    32641 tcgtttaact gccagggcga aacattaata tgcagtaaga aatcatcctt cagcgacgca
    32701 cgctgactaa aatgtctgaa ttcacccatt gccgttttaa taatctgata acccagctca
    32761 ttgataaacc cgatatcttc agcaatggta atgaacttca gcggtgaaat gatcccccgc
    32821 tccgcagaca cccaacggca caacgcctcc gcgcccagaa tggcgcgggt gttaatatca
    32881 acgatcggtt gatagacgag gaatagttcg ccaatttcca ttgcatggcg aatattacgc
    32941 gcaatccaga tattctcttc tatttcgttg agtttcgcgt catcacagaa aataaactct
    33001 gagaacatat ggtcacggat actggaaatc gccagtttca gtttttctgc gtaactccag
    33061 gcgttttccc cctgcaaagg ttcacaaatg gcagacttat ggatgcgcag attgcggtag
    33121 ccaaagctgc tgtcaaaatc gtttaccatc gctattttac gggtaaatgt ctgtacattt
    33181 tcccgacaca gaagtaaata gagatcggca ttgaatgtca cgatatcgca gcattgcgca
    33241 tatttctcgg caattcgctg acacaatttc ctgacgattt tattgcgctc atcaacacca
    33301 aacaccgctt ccacggcttc cagaccacac agtttgatga tccccacagc cagatactga
    33361 ttattgttag actcaataat cgccatattt ttaataaaac cactttcctg atcgtaagag
    33421 atcagtgaga gcaatttatt tgaccgttca atttcggcat ctttcatttc cgcgatcgaa
    33481 tttttgatgc tgataatctc tttcgcatcg ccttcacgaa ttttcagagc ctcgatttga
    33541 tccgttgagt caggcaaaaa cgccagcgta ttaaccagct ctgtcatttc agaaaattgc
    33601 cgacggaaca cacgagtggt cattaaataa accaccagca atacgataat aatgaacgca
    33661 aacggcagat aaaaaagttt atctgatgcg ttcaataaat taccgccagg ataataaaaa
    33721 tagatttcga ataatgcgtt gtttggcacc gctgatgttt tttcgatata ttcagtatcg
    33781 acagaatcaa taatattata attatcttcg ctattataaa taatcagttt ttcacgagcg
    33841 agttgattct tggcaatgat ctcatggcct tgtttcaaaa atagaacttc atcattagcg
    33901 ctgatttgat caagatactc gttcagatat cgccagttta aatcgacatg aattttatcc
    33961 accgctaaca aatcgtgatc tttgccgttg atgtgtagcg taaaagagat acatttttta
    34021 cccggacgat caaagcaatt gtatgccgga ttccagctgt tgttagagtc atctgaagcc
    34081 accgaccacg gtcgtttcga tgggttaaaa tcggcaaaaa taacccgccc tgactcgtcg
    34141 acaagcggtc catttacttg ttcctgatga taaacaacga ttttatcatt cgccctccgc
    34201 gaaaaaagat aatatttatt atcatcaagt accagtccca ccgagtctaa aaatggcatc
    34261 atttccattt taagaatcac ggcgcgttga atctcctctg tattttttaa taaatacagt
    34321 gagtccttta atgtcagggc cgaacgttca atatctttaa agaaatagcc aacgtttttc
    34381 tgaataagtt caaagcggct atcggcacgt tttaccgcgc gctccgatac cagttgatag
    34441 ttaatgatga aaaaaagacc aataaatgac agtgctgcca ataaaaataa aattatcagc
    34501 cttatcttta tcttttcgta taaactcagc atgttaatac atttaacaaa ataactatct
    34561 gaacgctgtg ccgctgcaaa aattgtccct tgctgcggct ttttaaccaa attacccgat
    34621 tctacaaaat cagcagaaag ttacaacact tgcttagggc aataatttcc tgtgaggtga
    34681 ttaccctttc aagcaatatt caaacgtaac tatcctttaa ttttcggatc cagcgcatcg
    34741 cgtaaaccat cgcccaacaa attgaacgcc agtacggtca gaaaaatagc cagggccgga
    34801 aaaacagcga catgcggcgc gataaccata tccgctcgag cctcattgag cattgctccc
    34861 cactctggtg tcggcggctg cgcaccgagg ccgagaaatg agaggctggc ggcagagata
    34921 atcgaggtac caatgcgcat ggtgaaaaac accacgatag aagagacggt cccaggcagg
    34981 atatgacgca acaaaacggt catatcgctg gcaccaatac tgcgtgctga ctcaataaag
    35041 gtttgctgtt tcaacaccag cgtgttgccg cgcaccaggc gggcaaacgc ggggatggaa
    35101 aaaatggcga ctgcaataat cacgttagca atgccgcttc ccaacaccgc aacaacagcg
    35161 atcgccagta aaatacccgg gaaggcaaac agcacatcgc aaatgcgcat gatcagccga
    35221 tcccaccagc cttcataata tccagcgagc aagcccagca acgtcccgat cgccgcaccg
    35281 ataaacacgg caaacacgcc cgccgccagc gagatttgcg caccaaccag gacacggctg
    35341 aaaatgtcac gccccagtga atcgacgcca aaccagtgct gcaaagaagg tccgttattc
    35401 agattgtcat aatcaaaata attttcggcg tcatagggag cgatccagcg tgcaaaaatg
    35461 gccaccacaa tcaataaaat aacgaataat gcggcggtca tcgccatatg ctgacggcga
    35521 aatcgtcgcc agaattcatg ccacggtgta cgtacctggt caggtttgac cagtggcatg
    35581 gcgtttaaca ccgcctgacg tcgccagtta aatagtcgca tccttacttg tacctgatag
    35641 ccgggttaat ggcggcgtaa agcacatcca ccactaagtt gataagaata aattccagcg
    35701 agaaaagcag aatttccgcc tgaatcaccg ggtaatcacg catttctacg gagtcaacga
    35761 gtaagcgtcc aagtcccggc cagttgaaaa ctttctccac aacgatggaa ccaccgagca
    35821 aaaagccaaa ctgtaagccc atcatggtca ctaccgggat catcgcgtta cgtagcccgt
    35881 gtttgaggac aacccaggtt tcgctcaccc ctttcgccct cgcggtacgc atataatctt
    35941 cgcttaaaac atcgacaaac gacgcgcggg taaagcgcgc catcacggcg gccactgccg
    36001 cgccgagcgt cagggagggt aaaatgtagt gctgccaact gtctgctccc acggtaggca
    36061 gccagcccag ttcaacggag aatacctgaa ttaaaagcat ccccagagca aatgccggaa
    36121 acgagatccc cgacaccgca atggtcatac tcaatcgatc cggccaacgg ttacgccaga
    36181 cggcggcgat aattcccgcc gccataccaa atataaccgc ccagaccata ctggttatgg
    36241 tcagccacag cgttggcata aagcggctgg caatctcatc ggcaaccgga cgacgcgaca
    36301 ccatcgacag gccaaaatcc ccctgcacag cattgctgat atagtgccag aactggtgat
    36361 acagcggctg atccaacccc agctgctgac gcaccagttc tataacctgc gcatcagctt
    36421 cgggcccggc aatcaatcgc gccggatcgc cgggcagcat atggacaaat aaaaacacca
    36481 gcaccgagac gataaacagc gtcggaatca accccagtaa gcgtttgata acgtaattaa
    36541 gcattccact ccctgcgttg cttattgcaa atccgcgtct tcaaagctga agccggtgtc
    36601 tggcatgatc caaaaaccgg tcaggttttt actgtgtgcc gacaccagtt tttctaccac
    36661 cagcgggatc cacggcgatt cttgccagat gatatcctgc gccgccttat ataagcgggt
    36721 cttttccgcc ggatcattag ttttcagtgc ctgagccagg aagtcatcca cctgtttatt
    36781 gctgtaaaac gcggtattaa acagcgtcgg tggccagttc tgcgaggcaa acagcggcga
    36841 tagtgcccag tccgcttcgc cggttgaagc cgaccagcca gtgtagaaca tccgcacgcc
    36901 gctctctttt tgccctttac cttcaacttc tgccgcccgc tgtccggcat ccatcgcagt
    36961 cacctgggct ttaatcccga cctgcgctaa ctgctgctgg gtaaattgca gcactttctg
    37021 cgcggtgctg tggttatgtg acgaccacag cgtggtactg aaaccgttgg gatatcccgc
    37081 ctctttcagt aattcgcgcg ctttcactgg atcgtaaggc cacggtttat aactttgcgc
    37141 gtaggcgata cttggcggta ccacaccagt agctggcgtt gcatagcccg caaaggcaac
    37201 tttcaccagc gccggacggt taatggcgta attcagcgcc tcacggacct tcgggttatc
    37261 gaacggcttt tgcgtcacgt tcatactgat ataacgctgc ataattgacg gactggccat
    37321 caactcgata tttttgtttt tctccagcag tgtggcctgc tcgtaaggaa tggggaaagc
    37381 aaactgcgct tcaccggttt gcagcattgc cgcgcgggtg ttgttatccg ccaccggacg
    37441 ccaggttatg ctgtccagtt tgggcaatcc tggctgccag taacccgcga attttttcac
    37501 cttcacaaaa tcggtctgat tccaggtatc cagttcatac ggtccggttc ccaccggata
    37561 aaaaccaatc tccttgccat atttttccag cgctgccggt gaaatcatcg cggtcgccgg
    37621 atgggcaaga atattaataa acgctgagaa cggctgtttg agggtaatct ttaccgttgt
    37681 cggatcgatc gcttccgttt tagcaatatt cttatacagg ttatagcgtt taagatgatt
    37741 cgccggatcg ctggcccggt ccagattcgc tttcaccgcc gcggcgttga aatcggtgcc
    37801 atcctggaat ttaatgcctt cccgcaattt cacggtgtaa gtaatgccgt catcggaaac
    37861 ggtataactc tccgccagca cgtttttcag tttcatctct ttatccagac cgaacagccc
    37921 ctggtaaaac gatttcgcta cggcctgaga taacgtgtca tttgcgtcat acggatcgag
    37981 cgtggtgaaa ttcgatccta ccgccaccac cacatctttg gcagcgaatg cacaagatgc
    38041 catcaacgct gtcgcaattc ccagcgccac taacccacta cggtgtacag ctcttgccat
    38101 tttattctcc gcctgaatgt tatctacgca tgaatgcgta ttctgattgt ggttgtgcga
    38161 cgtaatgccc cggcccgacg cattgcaacg agacggctgc cacctcttcg ccacgcagat
    38221 gaatattgct gggaagatcg tccgacagca gtacacgctg cggtcgttgt cgggacggtt
    38281 cagcgaccgg aactgccgcc agtaatttac gcgtataagg atgctgcggg ttttcgaaga
    38341 ccgcgcgccg tggaccaatt tcaacaattt gcccgagata catcaccgcc acacgatgac
    38401 taatccgctc taccaccgcc atatcgtggg agataaacag atacgcaatg ccgaaatcac
    38461 gctggagatc gagcaacaag ttgataatct gcccgcgaat agaaacatcc agcgccgaaa
    38521 cggcttcgtc ggcaatgatc acttttggat tcaatgccaa cgcgcgagca atgcagatgc
    38581 gctggcgctg accgccggaa aactcatgcg ggtaacgcca ggcatgttca ggtaacaggc
    38641 ccacgcgctc cagcaaccac gcaacgcgtg cagccgcgtc tttacctggc aataaaccgt
    38701 gtacacgcag cggttcgata atcgaatcac cgatggtctg acgtgggtcc agcgaagcgt
    38761 aagggtcctg aaaaataaac tgaatatccc ggcgtaatgc ctgaagtttg ccgggtgaca
    38821 aggtatcgat tcgctgaccg ttaaagataa tttcgccgcc ctgcgattcg accaggcgca
    38881 gcaacgcccg cccggtagtg gatttaccgc tgccagactc gcccaccagc gatagcgttt
    38941 cgccaggcca gagatcaaaa ctgactttct caacggcatg cacttcccgc gttacgcgat
    39001 tcaacaaacc gctgcgcaaa gggaaacggg tgacaagatt acgcactcgt
//
LOCUS       DACAOP010000036        38339 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.036, whole genome shotgun sequence.
ACCESSION   DACAOP010000036 DACAOP010000000
VERSION     DACAOP010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38339
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.036"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            49..672
                     /locus_tag="IT892_002071"
     CDS             49..672
                     /locus_tag="IT892_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HAP3135294.1"
                     /translation="MLKIIKQHKFAFLFTALLSTFFLNMFPPSAAGYELNTVLQIVAG
                     VNLLQRRYQVVSFIVLLIMFVTTHWLHPVNAMIQLYYGSYLVFFIILSVIVFRQVIFS
                     ARINTESICAALSGFLLIGYIGFFMFSAIENHMPGAFRGLSNDELQMMNELFYYSFIS
                     ILTVGYGDIVAVSWPARNATILVILTGYIYSLVFIARIVSGFSVSEK"
     gene            757..1008
                     /locus_tag="IT892_002072"
                     /pseudo
     CDS             757..1008
                     /locus_tag="IT892_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312493.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            complement(1297..1614)
                     /locus_tag="IT892_002073"
                     /pseudo
     CDS             complement(1297..1614)
                     /locus_tag="IT892_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612074.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            1769..1874
                     /locus_tag="IT892_002074"
                     /pseudo
     CDS             1769..1874
                     /locus_tag="IT892_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052659.1"
                     /note="PsiA; frameshifted; incomplete; partial in the
                     middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
     gene            2106..2264
                     /locus_tag="IT892_002075"
     CDS             2106..2264
                     /locus_tag="IT892_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HAP3135295.1"
                     /translation="MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAA
                     FMAYESGK"
     gene            complement(2502..3099)
                     /locus_tag="IT892_002076"
                     /pseudo
     CDS             complement(2502..3099)
                     /locus_tag="IT892_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235428.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3163..3450
                     /locus_tag="IT892_002077"
     CDS             3163..3450
                     /locus_tag="IT892_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135296.1"
                     /translation="MSTQNIHVSTASYTLLVAGKKKNTGEEWDVLEFSSLTELKKYRK
                     SHPEKMAFSYSYALSRGVDTQFRHINIAEADHFKQFLRQIKRAGLDIRAIC"
     gene            3569..4390
                     /locus_tag="IT892_002078"
     CDS             3569..4390
                     /locus_tag="IT892_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HAP3135297.1"
                     /translation="MRLASRFGRYNSIRRERPLTDDELMQFVPSVFSGDKHESRSERY
                     TYIPTINIINKLRDEGFQPFFACQSRVRDLGRREYSKHMLRLRREGHINGQEVPEIIL
                     LNSHDGSSSYQMIPGIFRFVCTNGLVCGNNFGEIRVPHKGDIVGQVIEGAYEVLGVFD
                     KVTDNMEAMKEIHLNSDEQHLFGRAALMVRYEDENKTPVTPEQIITPRRREDKQNDLW
                     TTWQRAQENMIKGGLSGRSASGKNTRTRAITGIDGDIRINKALWVIAEQFRKWKS"
     gene            complement(4686..5288)
                     /locus_tag="IT892_002079"
     CDS             complement(4686..5288)
                     /locus_tag="IT892_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001388590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAP3135298.1"
                     /translation="MVLLVVRTTNMLSLFVEWVKLFTDKVTRGGKMKKWMLSICLMFI
                     NEICHATDCFDLAGRDYKIDPDLLRAISWKESRYRVNAVGINPVTGYGSGLMQVDSQH
                     FNELARYGIKPEHLTTDPCMNIYTGAYYLAIAFKKWGVTWEAVGAYNAGFRKTERQNQ
                     RRLAYASDVYRIYTGIKSSKGIRIPVTKKSLTEINSVQNN"
     gene            5608..5991
                     /gene="traM"
                     /locus_tag="IT892_002080"
     CDS             5608..5991
                     /gene="traM"
                     /locus_tag="IT892_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome protein TraM"
                     /protein_id="HAP3135299.1"
                     /translation="MAKVNLYISNDAYEKINAIIEKRRQEGAREKDVSFSATASMLLE
                     LGLRVHEAQMERKESAFNQTEFNKLLLECVVKTQSSVAKILGIESLSPHVSGNPKFEY
                     ANMVEDIREKVSSEMERFFPKNDDE"
     gene            6178..6867
                     /gene="traJ"
                     /locus_tag="IT892_002081"
     CDS             6178..6867
                     /gene="traJ"
                     /locus_tag="IT892_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer transcriptional regulator
                     TraJ"
                     /protein_id="HAP3135300.1"
                     /translation="MYPMDRIQQKHARQIDLLENLTAVIQDYPNPACIRDETGKFIFC
                     NTLFHESFLTQDQSAEKWLLSQRDFCELISVTEMEAYRNEHTHLNLVEDVFIQNRFWT
                     ISVQSFLNGHRNIILWQFYDAAHVRHKDSYNQKTIVSDDIRNIIRRMSDDSSVSSYVN
                     DVFYLYSTGISHNAIARILNISISTSKKHASLICDYFSVSNKDELIILLYNKKFIYYL
                     YEKAMCIINTR"
     gene            6966..7361
                     /gene="traY"
                     /locus_tag="IT892_002082"
     CDS             6966..7361
                     /gene="traY"
                     /locus_tag="IT892_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001366159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer relaxosome protein TraY"
                     /protein_id="HAP3135301.1"
                     /translation="MKRFGTRSATGKMVKLKLPVDVESLLIEASNRSGRSRSFEAVIR
                     LKDHLHRYPKFNRAGNIYGKSLVKYLTMRLDDETNQLLIAAKNRSGWCKTDEAADRVI
                     DHLIKFPDFYNSEIFREADKEEDITFNTL"
     gene            7394..7759
                     /gene="traA"
                     /locus_tag="IT892_002083"
     CDS             7394..7759
                     /gene="traA"
                     /locus_tag="IT892_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001668211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system pilin TraA"
                     /protein_id="HAP3135302.1"
                     /translation="MNAVLSVQGASAPVKKKSFFSKFTRLNMLRLARAVIPAAVLMMF
                     FPQLAMAAGSSGQDLMASGNTTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVKFL
                     AGFAIISVFIAVGMAVVGL"
     gene            7774..8085
                     /gene="traL"
                     /locus_tag="IT892_002084"
     CDS             7774..8085
                     /gene="traL"
                     /locus_tag="IT892_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraL"
                     /protein_id="HAP3135303.1"
                     /translation="MSGDENKLKKYRFPETLTNQSRWFGLPLDELIPAAICIGWGITT
                     SKYLFGIGAAVLVYFGIKKLKKGRGSSWLRDLIYWYMPTALLRGIFHNVPDSCFRQWI
                     K"
     gene            8107..8673
                     /gene="traE"
                     /locus_tag="IT892_002085"
     CDS             8107..8673
                     /gene="traE"
                     /locus_tag="IT892_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HAP3135304.1"
                     /translation="MEHGARLSTSRVMAIAFIFMSVLIVLSLSVNVIQGVNNYRLQNE
                     QRTAVTPMAFNAPFAVSQNSADASYLQQMALSFIALRLNVSSETVDASHQALLQYIRP
                     GAQNQMKVILAEEAKRIKNDNVNSAFFQTSVRVWPQYGRVEIRGVLKTWIGDSKPFTD
                     IKHYILILKRENGVTWLDNFGETDDEKK"
     gene            8684..9388
                     /gene="traK"
                     /locus_tag="IT892_002086"
     CDS             8684..9388
                     /gene="traK"
                     /locus_tag="IT892_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system secretin
                     TraK"
                     /protein_id="HAP3135305.1"
                     /translation="MFGSLFFSCSVMAANGTLAPTVVPMVNGGQASIAISNTSPNLFT
                     VPGDRIIAVNSLDGALTNNEQTASGGVVVATVNKKPFTFILETERGLNLSIQAVPREG
                     AGRTIQLVSDLRGTGEEAGAWETSTPYESLLVTISQAVRGGKLPAGWYQVPVTKETLQ
                     APAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPASQLL
                     AGARMDVYVIRDGEGN"
     gene            9388..10815
                     /locus_tag="IT892_002087"
     CDS             9388..10815
                     /locus_tag="IT892_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraB"
                     /protein_id="HAP3135306.1"
                     /translation="MASINTIVKRKQYLWLGIVVVGTASAIGGALYLSDVDMSGNGET
                     VAEQEPVPDMTGVVDTTFDDKVRQHATTEMQVTAAQMQKQYEEIRRELDVLNKQRGDD
                     QRRIEKLGQDNAALAEQVKALGANPVTATGEPVPQMPASPPGPEGEPQPGNTPVSFPP
                     QGSVAVPPPTAFYPGNGVTPPPQVTYQSVPVPNRIQRKVFTRNEGKQGPSLPYIPSGS
                     FAKAMLIEGADANASVTGNESTVPMQLRITGLVEMPNSKTYDATGCFVGLEAWGDVSS
                     ERAIVRTRNISCLKDGKTIDMPIKGHVSFRGKNGIKGEVVMLNGKILGWAWGAGFVDG
                     IGQGMERASQPAVGLGATAAYGAGDVLKMGIGGGASKAAQTLSDYYIKRAEQYHPVIP
                     IGAGNEVTVVFQDGFQLKTVEEMALERTQSRAEEDNPESPVPVPPSAESHLNGFNTDQ
                     MLKQLGNLNPQQFMSGSQGGGNDGK"
     gene            10805..11395
                     /gene="traP"
                     /locus_tag="IT892_002088"
     CDS             10805..11395
                     /gene="traP"
                     /locus_tag="IT892_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraP"
                     /protein_id="HAP3135307.1"
                     /translation="MANNMSSRQACHAARYVVARVLRGLFWCLKYTVILPLATMALMA
                     LFVLWKDNTTPGKLLVKEINFVRQTAPAGQFPVSECWFSSSDSSGRSEIQDICHYRAA
                     DAADYVRETDRSLMQLVTALWATLALMYVSLAAITGKYPVRPGKMKCIRVVTADEHLK
                     EVYTEDASLPGKIRKCPVYLPDDRTNRNNGDKNEHA"
     gene            11349..11579
                     /locus_tag="IT892_002089"
     CDS             11349..11579
                     /locus_tag="IT892_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbD"
                     /protein_id="HAP3135308.1"
                     /translation="MTEQTETTEIKMNMRNINVITALSVPGKTVSDDFMHAVLSNCAT
                     RIVLPAPEKFGSESLPDNFNMTAVGVMKNSEI"
     gene            11591..11842
                     /locus_tag="IT892_002090"
     CDS             11591..11842
                     /locus_tag="IT892_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbG"
                     /protein_id="HAP3135309.1"
                     /translation="MNKLVSDGSVKKINYPVLYESGITPPLCEVSAPEPDAGGKRIVA
                     YVYKSSRSTVFENPDIVKTCTVRDLKKDFVNCDEKGEGQ"
     gene            11839..12354
                     /gene="traV"
                     /locus_tag="IT892_002091"
     CDS             11839..12354
                     /gene="traV"
                     /locus_tag="IT892_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system lipoprotein
                     TraV"
                     /protein_id="HAP3135310.1"
                     /translation="MKQISFFIPLLGTLLLSGCAGTSTEFECNATTSDTCMTMEQANE
                     KAKKLEQSSEAKPVAASLPRLAEGNFRTMPVQTVTATTPSGSRPAVTAHPEQKLLAPR
                     PLFTAAREVKTVVPVSSVTPVTPPRPLRTGEQTAALWIAPYIDNQDVYHQPSSVFFVI
                     KPSAWGKPRIN"
     gene            12489..12710
                     /gene="traR"
                     /locus_tag="IT892_002092"
     CDS             12489..12710
                     /gene="traR"
                     /locus_tag="IT892_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraR"
                     /protein_id="HAP3135311.1"
                     /translation="MSDEADEAYSVTEQLTMTGINRIRQKINAHGIPVYLCEACGNPI
                     PEARRKIFPGVTLCVECQAYQERQRKHYA"
     gene            12870..15497
                     /gene="traC"
                     /locus_tag="IT892_002093"
     CDS             12870..15497
                     /gene="traC"
                     /locus_tag="IT892_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein TraC"
                     /protein_id="HAP3135312.1"
                     /translation="MNNPLEAVTQAVNSLVTALKLPDESAKANEVLGEMSFPQFSRLL
                     PYRDYNQESGLFMNDTTMGFMLEAIPINGANESIVEALDHMLRTKLPRGIPLCIHLMS
                     SQLVGDRIEYGLREFSWSGEQAERFNAITRAYYMKAAATQFPLPEGMNLPLTLRHYRV
                     FISYCSPSKKKSRADILEMENLVKIIRASLQGASITTQTVDAQAFIDIVGEMINHNPD
                     SLYPKRCQLDPYSDLNYQCVEDSFDLKVRADYLTLGLRENGRNSTARILNFHLARNPE
                     IAFLWNVADNYSNLLNPELSISCPFILTLTLVVEDQVKTHSEANLKYMDLEKKSKTSY
                     AKWFPSVEKEAKEWGELRQRLGSGQSSVVSYFLNITAFCKDNNETALEVEQDILNSFR
                     KNGFELISPRFNHMRNFLTCLPFMAGKGLFKQLKEAGVVQRAESFNVANLMPLVADNP
                     LTPAGLLAPTYRNQLAFIDIFFRGMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSGG
                     FAVVFDMGDGYKSLCENMGGVYLDGETLRFNPFANITDIDQSAERVRDQLSVMASPNG
                     NLDEVHEGLLLQAVRASWLAKENRARIDDVVDFLKNASDSEQYAESPTIRSRLDEMIV
                     LLDQYTANGTYGQYFNSDEPSLRDDAKMVVLELGGLEDRPSLLVAVMFSLIIYIENRM
                     YRTPRNLKKLNVIDEGWRLLDFKNHKVGEFIEKGYRTARRHTGAYITITQNIVDFDSD
                     KASSAARAAWGNSSYKIILKQSAKEFAKYNQLYPDQFLPLQRDMIGKFGAAKDQWFSS
                     FLLQVENHSSWHRLFVDPLSRAMYSSDGPDFEFVQQKRKEGLSIHEAVWQLAWKKSGP
                     EMASLEAWLEEHEKYRSVA"
     gene            15494..15880
                     /gene="trbI"
                     /locus_tag="IT892_002094"
     CDS             15494..15880
                     /gene="trbI"
                     /locus_tag="IT892_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TrbI"
                     /protein_id="HAP3135313.1"
                     /translation="MSSTQKPADVTAERRSHWWWTVPGCLAMVLLNAAVSYGIVRLNA
                     PVTVAFNMKQTVDAFFDRASQKQLSEAQSKALSARFNTALEASLQAWQQKHHAVILVS
                     PAVVQGAPDITREIQQDIARRMRAEP"
     gene            15877..16509
                     /gene="traW"
                     /locus_tag="IT892_002095"
     CDS             15877..16509
                     /gene="traW"
                     /locus_tag="IT892_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TraW"
                     /protein_id="HAP3135314.1"
                     /translation="MRCRGLIALLIWGQSVAAADLGTWGDLWPVKEPDMLTVIMQRLT
                     ALEQSGEMGRKMDAFKERVIRNSLRPPAVPGIGRTEKYGSRLFDPSVRLAADIRDNEG
                     RVFARQGEVMNPLQYVPFNQTLYFINGDDPAQVAWMKRQTPPTLESKIILVQGSIPEM
                     QKSLDSRVYFDQNGVLCQRLGIDQVPARVSAVPGDRFLKVEFIPAEEGRK"
     gene            16506..17498
                     /gene="traU"
                     /locus_tag="IT892_002096"
     CDS             16506..17498
                     /gene="traU"
                     /locus_tag="IT892_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus assembly protein TraU"
                     /protein_id="HAP3135315.1"
                     /translation="MKRRLWLLMLFLFAGHVPAASADSACEGRFVNPITDICWSCIFP
                     LSLGSIKVSQGKVPDTANPSMPIQICPALPPLFRRIGLAIGYWEPMALTDVTRSPGCM
                     VNLGFSLPAFGKTAQGTAKKDEKQVNGAFYHVHWYKYPLTYWLNIITSLGCLEGGDLD
                     IAYLSEIDPTWTDSSLTTILNPEAVIFANPIAQGACAADAIASAFNMPLDVLFWCAGS
                     QGSMYPFNGWVSNESSPLQSSLLVSERMAFKLHRQGMIMETIGKNNAVCNEYPSPILP
                     KERWRYQMVNMYPDSGQCHPFGRSVTRWETGKNPPNTKKNFGYLMWRKRNCVFL"
     gene            17507..18145
                     /gene="trbC"
                     /locus_tag="IT892_002097"
     CDS             17507..18145
                     /gene="trbC"
                     /locus_tag="IT892_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TrbC"
                     /protein_id="HAP3135316.1"
                     /translation="MKLSMKSLAALLMMLNGAVMASENVNTPENRQFLKQQENLSRQL
                     REKPDHQLKAWAEKQVLENPLQRSDNHFLDELVRKQQASQDGKPRQGALYFVSFSIPE
                     EGLKRMLGETRHYGIPATLRGMVNNDLKTTAEAVLSLVKDGATDGVQIDPTLFSQYGI
                     RTVPALVVFCSQGYDIIRGNLRVGQALEKVAATGDCRQVAHDLLAGKGDSGK"
     gene            18142..19950
                     /gene="traN"
                     /locus_tag="IT892_002098"
     CDS             18142..19950
                     /gene="traN"
                     /locus_tag="IT892_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001756807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system mating-pair
                     stabilization protein TraN"
                     /protein_id="HAP3135317.1"
                     /translation="MKRILPLILALVAGMAQADSNSDYRAGSDFAHQIKGQGSSSIQG
                     FRPQESIPGYNANPDETKYYGGVTAGGDGGLKNDGTTEWATGETGKTITESFMNKPKD
                     ILSPDAPFIQTGRDVVNRADSIVGNTGQQCSAQEISRSEYTNYTCERDLQVEQYCTRT
                     ARMELQGSTTWETRTLEYEMSQLPAREVNGQYVVSITSPVTGEIVDAHYSWSRTYLQK
                     SVPMTITVLGTPLSWNAKYSADASFTPVQKTLTAGVAFTSSHPVRVGNTKFKRHTAMK
                     LRLVVRVKKASYTPYVVWSESCPFSKELGKLTKTECTEAGGNRTLVKDGQSYSMYQSC
                     WAYRDTYVTQSADKGTCQTYTDNPACTLVSHQCAFYSEEGACLHEYATYSCESKTSGK
                     VMVCGGDVFCLDGECDKAQSGQSNDFAEAVSQLAALAAAGKDVAALNGGGVRAFTGQA
                     KFCKKAAAGYSNCCKDSGWGQDIGLAKCSSDEKALAKAKSNKLTVSVGEFCSKKVLGV
                     CLEKKRSYCQFDSKLAQIVQQQGRNGQLRISFGSAKHPDCRGITVDELQKIQFNRLDF
                     TNFYEDLMNNQKIPDSGVLTQKVKEQIADQLKQAGQ"
     gene            19977..20234
                     /gene="trbE"
                     /locus_tag="IT892_002099"
     CDS             19977..20234
                     /gene="trbE"
                     /locus_tag="IT892_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbE"
                     /protein_id="HAP3135318.1"
                     /translation="MKVIFTSNRFIDFLIRLLITAIVISPVIIWSWDTVKETTADGML
                     AAAFVILYSGVLLFILYFCFSALTDLQKPDERKSDERNEDE"
     gene            20227..20970
                     /gene="traF"
                     /locus_tag="IT892_002100"
     CDS             20227..20970
                     /gene="traF"
                     /locus_tag="IT892_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TraF"
                     /protein_id="HAP3135319.1"
                     /translation="MNKALLPLLLCCFIFPASGKDAGWQWYNEKINPKEKENKPVPAA
                     PRQEPDIMQKLAALQTATKRALYEAILYPGVDNFVKYFRLQNYWTQQAGLFTMSARKA
                     MLAHPELDYNLQYSHYNGTVRNQLAADQAQQRQAIAKLAEHYGIMFFYRGQDPIDGQL
                     AQVINGFRDTYGLSVIPVSVDGVINPLLPDSRTDQGQAQRLGVKYFPAMMLVDPKQGS
                     VRPLSYGFISQDDLAKQFLNVSEDFKPNF"
     gene            20984..21325
                     /gene="trbA"
                     /locus_tag="IT892_002101"
     CDS             20984..21325
                     /gene="trbA"
                     /locus_tag="IT892_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbA"
                     /protein_id="HAP3135320.1"
                     /translation="MHTGDLCFFTGASLFIVGVVGYFFTGLNNKGVYLLSSFVFFVVN
                     VISVCMLPDNFLFLCGAVMNQCAVPVVSMAVSTMPIITKFDSFRRMFICIMLSAIWSG
                     VMWFFIISLVK"
     gene            complement(21306..21641)
                     /locus_tag="IT892_002102"
     CDS             complement(21306..21641)
                     /locus_tag="IT892_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin ArtA"
                     /protein_id="HAP3135321.1"
                     /translation="MEKRSFKEKLEIVRNIIRESLSGNAAFALLVYSLLHTLPIKTFA
                     DLFVTILLFIAIIAVVIWLFLIIYVYFCDLFRSHWIAVWFILWSVVINLTIGFGIYDK
                     LAPVISLMK"
     gene            21722..22006
                     /gene="traQ"
                     /locus_tag="IT892_002103"
     CDS             21722..22006
                     /gene="traQ"
                     /locus_tag="IT892_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     chaperone TraQ"
                     /protein_id="HAP3135322.1"
                     /translation="MISKRRFSLPRLDITGMWVFSLGVWFHIVARLVHSKPWMAFFLA
                     ELIAAILVLFGAYQVLDAWIARVSREEREALEARQQAMMAEQQEGGHVSH"
     gene            21993..22547
                     /gene="trbB"
                     /locus_tag="IT892_002104"
     CDS             21993..22547
                     /gene="trbB"
                     /locus_tag="IT892_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly thiol-disulfide isomerase TrbB"
                     /protein_id="HAP3135323.1"
                     /translation="MSLTKLLPVILLMMATGVQASTRDEIERLWHPQGMAAQPAQPAA
                     DTPARTDKTEKPAPRWFRLSNGRQVNLADWKVVLFMQGHCPYCHQFDPVLKQLAQQYG
                     FSVFPYTLDGQGDMAFPEALPVPPDVMQTFFPNIPVATPTTFLVNVNTLEALPLLQGA
                     TDAAGFMARMDTVLQMYGGKKGAK"
     gene            22477..22850
                     /gene="trbJ"
                     /locus_tag="IT892_002105"
                     /pseudo
     CDS             22477..22850
                     /gene="trbJ"
                     /locus_tag="IT892_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444236.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbJ"
     gene            22804..23196
                     /gene="trbF"
                     /locus_tag="IT892_002106"
     CDS             22804..23196
                     /gene="trbF"
                     /locus_tag="IT892_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F-type conjugal transfer protein TrbF"
                     /protein_id="HAP3135324.1"
                     /translation="MTKNKKNQEFKIRKIRRNIEYSFRGSDRYFDLFIVFLVAGIVLW
                     AVMHVIFDVCIDSWMADPKLLNFQYMWNVLMKVIPFTLWALAAGFLVTFFLSPMCELI
                     FGNIMIFLLKRRMRRENTLREGKNDATH"
     gene            23180..24556
                     /locus_tag="IT892_002107"
     CDS             23180..24556
                     /locus_tag="IT892_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HAP3135325.1"
                     /translation="MMPRIKPLLVLCAALLTVTPAASADVNSDMNQFFNKLGFASNTT
                     QPGVWQGQAAGYAYGGSLYARTQVKNVHLISMTLPDINAGCGGIDAYLGSFSFINSEQ
                     LQRFVKQIMSNAAGYFFDLALQTTVPEIKTAKDFLQKMASDINSMNLSSCQAAQGIIG
                     GLFPRTQVSQQKVCQDIAGESNIFADWAASRQGCTVGGKSDSVRDKASDKDKERVTKN
                     INIMWNALSKNRMFDGNKELKEFVMTLTGSLVFGPNGEITPLSARTTDRSIIRAMMEG
                     GTAKIYHCNDSDKCLKVVADTPVTISRDNALKSQITKLLASIQNKAVSDTPLDDKEKG
                     FISSTTIPVFKYLVDPQMLGVSNSMIYQLTDYIGYDILLQYIQELIQQARAMVATGNY
                     DEAVIEHINDNINDATRQIAAFQSQVQVQQDALLVVDRQMSYMRQQLSARMLSRYQNN
                     YHFGGSTL"
     gene            24553..27378
                     /gene="traG"
                     /locus_tag="IT892_002108"
     CDS             24553..27378
                     /gene="traG"
                     /locus_tag="IT892_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer mating pair stabilization
                     protein TraG"
                     /protein_id="HAP3135326.1"
                     /translation="MNEVYVIAGGEWLRNNLNAIAAFMGTRTWDSIEKIALTLSVVAV
                     AFMWVQRHNVMDLLGWAAVFVLISLLVNIRTSVQIIDNSDLVKVHRVDNVPVGLAMPL
                     SLTTRIGHAMVASYEMIYTQPDSFTYSKTGMLFGAELVSKSTDFLSRNPEIANLFQDY
                     VQNCVMGDIYLNHKYTLEELMASNDPYTLIFSRPSPLRGVYDSNNNFVTCKDASVSLK
                     DKLNLDTQSGGKTWHYYAQQLFGGRPDPNLLFSTLIGDSYRYFYDSSKSASQIIRQNV
                     TINALKEGITSYAARNGDSASLVNLATTSSMEKQRLAHVSIGHVAMRTLPMTQTILTG
                     IAIGIFPLLVLAAVFNKLTLSVLKGYVFALMWLQSWPMLYAILNSAMTFYAKQNGAPV
                     VLSEISQIQLKYSDLASTAGYLSMMIPPLSWMMVRGLGAGFSSVYSHFASSAISPTAS
                     AAGSVVDGNYSYGNMQTENVNGFSWSTNSTTSFGQMMYQTGSGATTTQTRDGNMVMDA
                     SGAMSRLPVGINATRQIAAAQQEMAREASNRAESALHGFSSSIASAWNSLSQFGSNRG
                     SSDSVTGGADSTMSAQDSMMASRMRSAVESYAKAHNISNEQATQELASTSTRLSGGMY
                     ADAHAEWGVKPKILGVGGGVGIRGGFKGSLDATDDDSHSASSGSRATHDARHDIDARA
                     TQDFKEASDYFTSRKVSESGSHTDNNADSRVDQLSAALNSAKQSYDQYTTNMTRSHEY
                     AEMASRTESMSGQMSEDLSQQFAQYVMKHAPQDAEAILTNTSSPEIAERRRAMAWSFV
                     QEQVQPGVDNAWRESRGDIGKGMESVPSGGGSQDIIADHQGHQAIIDQRTQDSNIRND
                     VKHQVDNMVTEYKGNIGDTQNSIHGEENIVDRQYSELKNNHKQEEIQQNNRYNEENKR
                     QKLIPTPSEDALKQMVDDKKERLKGPL"
     gene            27375..27830
                     /gene="traS"
                     /locus_tag="IT892_002109"
     CDS             27375..27830
                     /gene="traS"
                     /locus_tag="IT892_002109"
                     /inference="COORDINATES: protein motif:HMM:NF010304.0"
                     /note="TraS, as the term is used in F-like plasmids, is a
                     plasmid entry exclusion protein. It interacts with the
                     F-like plasmid mating stabilization protein TraG; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer entry exclusion protein TraS"
                     /protein_id="HAP3135327.1"
                     /translation="MITHYDIKMEMQKLKEVLSVEGVNIPSLLQVIKPGTYVFLWVLL
                     WPTFLRLVSVKSDVRDVGFDICASGMMGFLLFVAITNGMMLYLAIPDSFRKDSKIINF
                     MYSKSKTYILLFLIVFFYGFVYAFYLICFCTNDYIHIIFLGVYHRYKSL"
     gene            27899..28630
                     /gene="traT"
                     /locus_tag="IT892_002110"
     CDS             27899..28630
                     /gene="traT"
                     /locus_tag="IT892_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HAP3135328.1"
                     /translation="MKTKKLMMVALVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIW
                     LEPASERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKAD
                     KMDLRESQGWLNRGYEGAAVGAALGAGITGYNSSSAGATLGVGLAAGLVGMAADAMVE
                     DVNYTMITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNAN
                     KVNLKFEEAKPVLEDQLAKSIANIL"
     gene            28882..31062
                     /gene="traD"
                     /locus_tag="IT892_002111"
     CDS             28882..31062
                     /gene="traD"
                     /locus_tag="IT892_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000009331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="HAP3135329.1"
                     /translation="MSFNAKDMTQGGQIASMRIRMFSQIANIMLYCLFIFFWILVGLV
                     LWVKISWQTFVNGCIYWWCTTLEGMRDLIKSQPVYEIQYYGKTFRMNAAQVLHDKYMI
                     WCGEQLWSAFVLATVVALVICLITFFVVSWILGRQGKQQSENEVTGGRQLTDNPKDVA
                     RMLKKDDKDSDIRIGDLPIIRDSEIQNFCLHGTVGAGKSEVIRRLANYARKRGDMVVI
                     YDRSGEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNTANTLIPMGTKEDP
                     FWQGSGRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTFLRNSPAANLVEEKIE
                     KTAISIRAVLTNYVKAIRYLQGIEHNGEPFTIRDWMRGVREDQKNGWLFISSNADTHA
                     SLKPVISMWLSIAIRGLLAMGENRNRRVWFFCDELPTLHKLPDLVEILPEARKFGGCY
                     VFGIQSYAQLEDIYGEKAAATLFDVMNTRAFFRSPSHKIAEFAAGEIGEKEHLKASEQ
                     YSYGADPVRDGVSTGKDMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQTRP
                     KVAPEFIPRDINPEMENRLSAVLAAREAEGRQIASLFEPDVPEVVSGEDVTQAEQPQQ
                     PQQPQQPQQPVSPAINDKKSDSGVNVPAGGIEQELKMKPEEEMEQQLPPGISESGEVV
                     DMAAYEAWQQENHPDTQQQMQRREEVNINVHRERGEDVEPGDDF"
     gene            31062..36332
                     /gene="traI"
                     /locus_tag="IT892_002112"
     CDS             31062..36332
                     /gene="traI"
                     /locus_tag="IT892_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /protein_id="HAP3135330.1"
                     /translation="MMSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQ
                     GSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYDLTFSAPKSVSMMAMLGGDKRL
                     IDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHA
                     VVANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVV
                     GKHGMWEMPGVPVEAFSGRSQTIRETVGEDASLKSRDVAALDTRKSKQHVDPEIKMTE
                     WMQTLKETGFDIRAYRDAAEQRAYTRTQTPGPASQDGPDVQQAVTQAIAGLSERKVQF
                     TYTDVLARTVGILPPEAGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSV
                     RALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVA
                     ELVMMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLLEGMAFTPGSTVIVD
                     QGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQR
                     PATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVL
                     GHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSHSLT
                     LRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVTSV
                     SEDAMTVVVPGRAEPATLPVSDSPFTALKLENGWVETPGHSVSDSATVFASVTQMAMD
                     NATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETSLETAISHQ
                     KSALHTPAQQAIHLALPVVESKNLAFSHVDLLTEAKSFAAEGTSFTELGREIDAQIKR
                     GDLLHVDVAKGYGTDLLVSRASYEAEKSILRHILEGKEAVTPLMERVPGELMEKLTSG
                     QRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAV
                     GEMRSAGVDAQTLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIA
                     AGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQTPELREAVYSLINR
                     DVEKALSGLESVKPSQVPRLEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLKGEAFPDI
                     PMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDQRVLNSMIHDAREKAGELGKEQVMVP
                     VLNTANIRDGELRRLSTWETHRDALALVDNVYHRIAGISKDDGLITLQDAEGNTRLIS
                     PREAVAEGVTLYTPDKIRVGTGDRMRFTKSDRERGYVANSVWTVTAVSGDSVTLSDGQ
                     QTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKQMAGFESAYVAL
                     SRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKPDREVMNAQRLFSTARELRDV
                     AAGRAVLRQAGLAGGDSPARFIAPGRKYPQPYVALPAFDRNGRSAGIWLNPLTTDDGN
                     GLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIARDNPDSGVVVRIAGE
                     GRPWNPGAITGGRVWGDIPDNSVQPGAGNGESVTAEVLAQRQAEEAIRRETERRADEI
                     VRKMVENKPDLPDDKTELAVRDIAGQERDRTATSERETALPESVLRESQREREAVREV
                     ARENLLQRLLQQMERDMVRDLQKEKTLGGD"
     gene            36352..37098
                     /gene="traX"
                     /locus_tag="IT892_002113"
     CDS             36352..37098
                     /gene="traX"
                     /locus_tag="IT892_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     acetylase TraX"
                     /protein_id="HAP3135331.1"
                     /translation="MTTDNTNTIRNDSLAARTDTWLQSFLVWSPGQRDIIKTVALVLM
                     VLDHINLIFQLKQEWMFLVGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGIIAQF
                     AYYLAGFPWYEGHILFAFAVVAQVLTWCETRSGWRTAAAILLMAQWGPLSGTSYGIAG
                     LLMLAVSHRLYRAEDRAERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSC
                     AGKSLPRFWPGDFFPTFYACHLAVLGVLAL"
     gene            37153..37713
                     /locus_tag="IT892_002114"
     CDS             37153..37713
                     /locus_tag="IT892_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /protein_id="HAP3135332.1"
                     /translation="MTEQKRPVLTLKRKTEGTAPVRSRKTIINVTTPPKWKVKKQKLA
                     EKAAREAELAAKKAQARQALSIYLNLPSLDEAVNTLKPWWPGLFDGDTPRLLACGIRD
                     VLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEET
                     YAAERLDKIRRQNRIKAELQAVLDEK"
     gene            37846..38058
                     /locus_tag="IT892_002115"
     CDS             37846..38058
                     /locus_tag="IT892_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135333.1"
                     /translation="MNGFRNSSRNGQVWCWQRAGSRAVILEVSGRWMEAAEGWRRAAC
                     VAPRTDWQQFARKRAEHCHRRCRGRV"
BASE COUNT         9578 a         9010 c        10670 g         9081 t
ORIGIN      
        1 gggcattatc tgaacataaa acactatcaa taagttggag tcattaccat gttaaagata
       61 ataaaacaac acaaatttgc ttttcttttc acagcactgc tgagcacctt ctttctcaat
      121 atgtttccac cgagcgctgc agggtacgag ttgaataccg tgctgcagat tgtggcgggc
      181 gttaatctgt tgcagcgtcg ctatcaggtc gtttcattta ttgtgttgct gataatgttt
      241 gtcaccacac actggctgca tcccgtcaat gccatgatac agctgtacta cgggagttat
      301 ctggtctttt tcatcattct gtcagtgatt gtgttccgcc aggtgatttt ctccgcccgg
      361 ataaacacag agtccatctg cgctgcacta agtggctttc tgcttattgg ctatataggg
      421 tttttcatgt tttctgcgat agaaaatcat atgcctggcg cgttccgtgg actgtcaaat
      481 gatgagttgc agatgatgaa tgaacttttt tattattctt ttatcagtat tctgaccgta
      541 ggctatggcg atattgttgc cgtcagctgg ccggctcgta atgccactat tctggttatt
      601 ctcacgggct atatttactc actggtcttt attgcccgca tcgtcagtgg attttcggtc
      661 tcagaaaaat aactctttgt accagctacc agtcggctgt actacgggtt cctgagtccg
      721 gcaaaacggc atcgtgtatc gttccggtcg agtaggcagc ctaacccgac cactgaaaac
      781 gtcgcggcag agctgaagct gctgacggaa aattgctgcg atagtgggat ttctctggga
      841 ggtggatcgc cgcacgactg cgcgaaagga attgcgttgg tcgcaaccaa tggtggaaat
      901 attcgtgatt atgaaggtgt tgatcgttcc gcgaaaccgc tgctgccaat gattgcgatt
      961 aacaccactg cgggtacggc ttcggaaatg acccgtttct gtattatggg gtcagtttgg
     1021 atatcggaac ttattgtact ataagggctt ccccggcatg tcaacgccgg ttttatagtt
     1081 tctgtctgct cgtcagtaaa ataaagggga gagactgcgg tactataaac ggccatgatg
     1141 aatcgttatc gattcgggcc ctgatgaaag acgcgcgtga ggttcttgtt cgttaagcgg
     1201 atacgtatat cctgtacaat agccagatag gcctcacggg gtctaaccct ttttcatcaa
     1261 cgagttgcag gtcagatggt tatactgctt tgtgctttag ctggctgagt acagcctgaa
     1321 atcatcaccg taatgcaacg atgcccagca cagcctcgcg tttttggcgg cgatggctac
     1381 aacagcccgc cagtaccccc tgcgctcaac caacgtacaa acccaacggc tgaatgagtc
     1441 agtccttttc tctgcaccaa tcaaaaccga acgggccccc tgaaccagaa gcgttcgcag
     1501 atatgaatcg cccgctttcg ttattctgcc aagctttgat tttccgccac tgctgtactg
     1561 tgatggtgta agtcccagcc aggctgccag ttggcgtcca ttcttaaaat catggcgttg
     1621 acaaggcaag tatggcagcc agagaggccg gttgcgtatt ttcatgaaag gagatcagtg
     1681 aaggtaattt aaaaacggtt ctgtgaaagt gacacgaacc gatctccatc gatgttactc
     1741 accgatctcc ttcacggtaa tacgcaccgg tcacgctgtc cgtgagatgg agcggtggat
     1801 ggtgccgaac aaactccggg aggcagcgtg atgcggcaac aatcacacag attacccgta
     1861 aacagtctga atgagcgggt tattttcagg aaaagtgagt gtggtcagcg tgcagggata
     1921 tgggctatga tgtgcccggc gcttgaggct ttctgcctca tgacgtgaag gtggtttgtt
     1981 accgtgttgt gtggcagaag gacaaaagcc ccgtagttaa tttttcatta acccacgagg
     2041 cccctgcatg cttagacaac atcaggatag cctcttaccg cgctttgcgc aaggagaaga
     2101 aggccatgaa actaccacgc agctctcttg tctggtgtgt gttgatcgtg tgtctcacac
     2161 tgttgatatt cacttatctg acacgaaaat cgctgtgcga gattcgttac agagacggat
     2221 acagggaggt ggcggctttc atggcttacg aatccggtaa gtagcaacct ggaggcgggc
     2281 gcaggcccgc cttttcaggg ctgatgctgg tctgactgca ctgaagcgcc tttataaagg
     2341 ggttgctggt tcgccggtgg cccctttctc cttgctggca ttgtacgggc atgaacaacc
     2401 agactgccag gaaggccatt tccctccggg aacggggatg aacgtgcgcc tgcggcgccc
     2461 gttcttttcc cccgccttct ctgtttatga cctgtcagaa atcacatcac cttccctttg
     2521 attattctct ttttcctcct gttctgactc tgattactgc tgccctgatt attgtctgtt
     2581 ttgttgttct cctgcttatg ccttttccgg gcgtccccct ggcggggcgg gctgtcgtga
     2641 acggagccag cgaagctgtc tccgccctgg cgggcttcca tcccggacgc gaaaccccgg
     2701 gcttgcagcg accgttccgg tcgcgccgcc tctgtcgcgc cgtggcctgc gctccttaca
     2761 tcccggcaaa aggccgccgg gatgtaaggc gcaacgccgt ttcgcaaacc gcgcttcacg
     2821 tcgttgcggc gggtgcctgc ccgttgttgt gtccggtgcc attcacctgt ttaagcccct
     2881 gtcgccgggg gcaaagacag ccacaaccgt ctccgccagt ccaggggtga aatgtacatc
     2941 ccgcaaaact ttttgcccaa aagcaggcaa aaacttttgc ggtctgcccc cagacagtcg
     3001 tttccggccg tggcagtgat gccccttgcg gcgaaggttc tcaaaaaggt gatggtgaat
     3061 accggaggga acaaaaggca ggtccccgca aaacgtcaaa accgcggctc ccgaaactca
     3121 aaagatgatg ggggctgaaa accagagaga ggagaaagca ggatgagtac ccaaaatatc
     3181 cacgttagca ccgcgtcgta cacgcttctt gttgccggga agaaaaaaaa caccggggaa
     3241 gagtgggacg tcctagaatt cagcagcctg actgagctga aaaaatatcg caaaagccac
     3301 ccggaaaaga tggccttcag ctatagctac gcgctcagcc ggggtgtgga tacgcagttc
     3361 cgccatatca acattgcgga agccgatcac ttcaaacagt tcctgcgtca gattaagcgt
     3421 gccggcctcg atatccgggc gatctgctga ccggatgtga tgaatatccc tcctgattgt
     3481 tgctgacttg ttaatgatgg tagggaggga tgatattaag cggaaaaatt ttttattaaa
     3541 tttattcttt cataaaggag tagctgttat gcgattagct tcccgttttg gtcggtataa
     3601 ttccatccgc cgtgaacgtc ctttaacgga tgatgaatta atgcagttcg tgccttcggt
     3661 attttccggt gataaacatg agtcccggag tgaacgttat acgtatattc caacaatcaa
     3721 tatcatcaat aagttacgtg atgaaggttt ccagccattc tttgcctgtc agagtcgggt
     3781 tcgtgatttg ggacgtcgcg aatacagtaa acatatgtta cgtcttcgca gggaagggca
     3841 tattaacggg caggaagttc ctgaaattat cctgcttaat tcacatgatg gttcatccag
     3901 ttatcagatg atccccggaa tttttcgttt tgtctgcaca aatggcctgg tgtgcggaaa
     3961 taattttggc gaaatccgcg ttccacataa aggtgatatt gtcgggcagg ttatcgaggg
     4021 agcgtatgaa gtgctcggtg tctttgataa ggtcactgat aatatggagg cgatgaaaga
     4081 aattcatctt aacagtgacg agcaacattt atttggtaga gctgcactga tggtcaggta
     4141 tgaagatgaa aataaaacgc cagtgacgcc tgaacaaata attactcccc gtcgtcggga
     4201 ggataaacag aacgatctct ggacaacctg gcagcgggct caggagaata tgataaaagg
     4261 tggattatcg gggcgaagtg cctccgggaa aaataccagg acaagagcca ttacaggtat
     4321 tgatggtgat ataaggatca acaaggcgtt gtgggtgatt gctgaacagt tcagaaagtg
     4381 gaagtcatga taatataagt aaagccccga aaaattttcg gggctttact tatattatca
     4441 ttcttcggca tcgctgtgtc gtctgatata catcaatttc atcaactggc tttccggttg
     4501 tctgtaaata ttgtgcccgc gaaaaatggt ctgacaggag gctgcgcagt taccgggtat
     4561 atataatatg ggttcccgct tcgcgggact tcggccagtc agcattatca ctcatatgat
     4621 atttttgtgt gtggccttcc atgccgcttt tgcggcataa ccggtatctg acaatgtctg
     4681 taagattaat tattctgcac gctgttaatt tccgtaagtg atttctttgt gaccggaatc
     4741 cggatacctt tactgctttt tatcccggta taaatccggt aaacatctga tgcgtaggca
     4801 agacgtctct ggttctggcg ttcggttttc ctgaatcctg cattatatgc accaacggcc
     4861 tcccaggtga cgccccattt tttaaatgct attgccagat aataagcacc ggtataaatg
     4921 ttcatgcagg gatctgttgt cagatgttcc ggcttaattc cgtagcgggc cagttcgtta
     4981 aaatgctggg aatctacctg catcagtccg ctgccatatc ccgttaccgg attaataccg
     5041 acggcattaa cccggtaacg ggattctttc catgatattg ctctcagtaa atcaggatct
     5101 attttgtaat cccgtcctgc aagatcaaag caatcagtgg catggcagat ctcatttata
     5161 aacatcaggc agatggataa catccatttt ttcatttttc cacctctggt gactttatcc
     5221 gtaaataatt taacccactc cacaaaaagg ctcaacatgt tggtggttct caccaccaaa
     5281 agcaccacac cccacgcaaa aacaagtttt tgctgatttt tctttataaa tagagagtta
     5341 tgaaaaatta gtttctctta ctctctttat gatatttaaa aagcgatgtc ggcgcggcta
     5401 caacaacgcg ccgacaccgc tttgtagggg tggtactgac tatttttata aaaaacatta
     5461 ttttatatta ggggtgctgc tagcggcgcg gtgtgttttt ttataggata ccgctagggg
     5521 cgctgctagc ggtgcgtccc tgtttgcatt atgaatttta gtgtttcgaa attaacttta
     5581 ttttatgttc aaaaaaggta atctctaatg gctaaggtga acctgtatat cagcaatgat
     5641 gcctatgaaa aaataaatgc gattattgag aagcgtcgac aggaaggggc aagggaaaaa
     5701 gatgtcagtt tttcagcaac agcttcaatg cttcttgaac tggggcttcg tgtacatgag
     5761 gctcagatgg agcgtaaaga gtctgcattt aatcagactg agtttaataa attgcttctc
     5821 gaatgcgttg taaaaacaca atcatcagta gcgaaaattt tgggtattga gtctctcagt
     5881 cctcatgtct ccggaaatcc aaagtttgaa tatgccaata tggttgaaga tatcagggag
     5941 aaggtatcat ctgagatgga acgatttttt ccaaaaaatg atgatgaata aaagaaattt
     6001 gacttcgttc aaatatcaga gtttttatga tttaaaaagg tgacagtacg aaagataatt
     6061 agtatattaa ttacgtggtt aatgccacgt taaaatttga atttgaaaat cgccgatgca
     6121 gggagttctc tcctccctgc atcgactgtc catagaatcc tttgtgagga ggttcctatg
     6181 tatccgatgg atcgtattca acaaaaacat gctcgtcaaa tagatctgct ggaaaatctg
     6241 acggcagtta ttcaggatta tccaaatcca gcctgtatca gggacgaaac tggaaaattt
     6301 attttttgca atacgctgtt tcatgagtca tttcttacac aagatcaaag tgctgaaaaa
     6361 tggcttctgt cgcagagaga tttttgtgaa ttgatctctg tcacagagat ggaagcatac
     6421 aggaatgagc atacgcatct taatcttgta gaggatgttt ttattcagaa cagattctgg
     6481 acaatatctg tccagtcatt tcttaatgga cacagaaata ttattctgtg gcaattttat
     6541 gatgctgctc atgttcgtca taaagacagt tataatcaaa aaacgattgt cagtgatgat
     6601 atcagaaata taatcagaag aatgagtgat gattcttctg tatcatcata tgtaaatgat
     6661 gtcttttact tatatagcac cggaatcagt cataatgcta tagcaagaat attaaatata
     6721 tccatctcca catcaaagaa acacgcatct ctgatatgcg actacttctc tgtttctaat
     6781 aaagatgagt taattatatt actctacaat aaaaagttta tttattattt atacgagaag
     6841 gctatgtgta tcataaatac gcgttaataa ggtgttaata aaatatagac tttccgtcta
     6901 tttacctttt ctgattattc tgcaaacata agtggtaacc agaagataaa cagcgggagg
     6961 tgttattgaa aagatttggt acacgttctg caacaggtaa gatggtaaaa ctaaaattac
     7021 ctgtagatgt ggaaagtcta ttaattgagg caagtaacag aagcggaaga agtcgatcgt
     7081 ttgaggcagt aataagactt aaagatcatc ttcaccgcta tccaaagttt aacagggcag
     7141 ggaatatcta tggtaagtcg ctggttaagt atctgacaat gcgtctggat gatgaaacta
     7201 accagctact tattgcagcc aaaaatcgta gtggatggtg taaaacagat gaggctgcag
     7261 acagagttat tgatcatttg atcaagtttc ctgattttta taactcggag atattcaggg
     7321 aggcagataa agaggaagat ataacattta atacactcta gttttattca tttatccgaa
     7381 attgaggtaa cttatgaatg ctgttttaag tgttcagggt gcttctgcgc ccgtcaaaaa
     7441 gaagtcgttt ttttctaaat tcactcgtct gaatatgctt cgcctggctc gcgcagtgat
     7501 cccggctgct gttctgatga tgttcttccc gcagctggcg atggccgccg gcagcagtgg
     7561 tcaggacctg atggcaagcg gtaacaccac ggttaaggcg accttcggta aggactccag
     7621 tgttgttaaa tgggttgttc tggctgaagt tctggtcggt gctgtcatgt acatgatgac
     7681 caaaaacgtc aagttcctgg ccggttttgc catcatctct gtatttattg ctgtgggtat
     7741 ggccgtcgtt ggcctctgac aggaaataaa acgatgtcgg gagacgagaa taaacttaag
     7801 aaatatcgtt tcccggaaac actgaccaac cagagccgct ggtttggcct gccactggat
     7861 gaactgatcc ccgcagcaat ctgtattggc tggggtatca caacatcgaa atatctgttc
     7921 ggtattggtg cagcggttct ggtttatttc gggattaaaa aactgaaaaa agggcggggc
     7981 agttcctggt tacgtgacct gatttactgg tatatgccaa cagccctgct gcgcggtatt
     8041 tttcataatg ttcccgattc gtgtttccgg cagtggatta aatagaactg ataccaggat
     8101 tgttatatgg aacacggtgc ccgtttaagt accagtcgtg taatggccat cgcctttata
     8161 tttatgtcag tgcttattgt tctcagcctc tctgttaacg tcattcaggg ggtgaataac
     8221 taccgtcttc agaatgagca acgcactgcc gtgacgccaa tggcatttaa tgcccccttt
     8281 gccgtgtcac agaacagtgc cgacgcctct tatttacagc agatggcgct gtcatttatt
     8341 gccctccgtc tgaatgtttc atcagaaacc gtcgatgcct cacatcaggc gcttctgcaa
     8401 tatatccgcc cgggcgcaca gaaccagatg aaagttattc tggctgaaga agcgaagcgt
     8461 attaaaaacg ataacgtgaa ctcagccttt ttccagacca gtgttcgtgt ctggcctcag
     8521 tatggccgtg tggaaattcg aggtgtgctt aaaacctgga ttggtgattc aaaacctttc
     8581 actgatatca aacattacat ccttattctg aagcgggaaa acggggtgac ctggctggat
     8641 aatttcgggg aaacagacga tgagaaaaaa taatacggca ataatattcg gcagcctgtt
     8701 tttttcctgc agcgtgatgg ccgcaaacgg tacgctggcc cccaccgtgg tgccaatggt
     8761 gaacggtggt caggccagta ttgccatcag caataccagc ccgaatctgt ttaccgttcc
     8821 cggtgaccgg attatcgccg tgaacagtct ggatggtgcc ctgaccaata atgagcagac
     8881 cgcctccggc ggtgtggtgg ttgccaccgt caacaaaaag ccctttacgt tcattctgga
     8941 aacagaacgt ggtctgaatc tttccattca ggccgttccc cgtgaaggcg cggggcgtac
     9001 cattcagctg gtcagtgacc tgcgcggaac cggagaagaa gccggtgcgt gggaaacgtc
     9061 cacgccttac gaatccctgc ttgtgaccat cagccaggcc gtccgtggcg gaaaattacc
     9121 cgcaggctgg tatcaggtcc cagtgacaaa ggaaaccctg caggccccgg cggggctgtc
     9181 ttcagtggca gatgccgtat ggacggggaa tcacctgaag atggtccgct ttgccgtgga
     9241 aaataaaaca ctgtctgccc tgaatatccg ggaaagtgac ttctggcagc cgggaacccg
     9301 tgccgtgatg ttcagccagc ctgccagcca gttactggca ggtgcgcgca tggatgtgta
     9361 tgtcatccgt gacggggagg gcaactgatg gccagtatca ataccattgt gaaacgcaag
     9421 cagtacctgt ggctggggat tgtggttgtc ggtacagcct ccgcgattgg tggggcactg
     9481 tatctgtctg atgtggacat gtccggtaac ggtgaaaccg tggctgaaca ggagcctgtg
     9541 ccggatatga ccggtgtggt ggatacgacc tttgatgaca aggtgcgtca gcatgccacc
     9601 accgagatgc aggtgacggc agcgcagatg cagaagcagt atgaggaaat ccgtcgtgag
     9661 ctggatgttc tgaacaaaca gcgcggtgat gaccagcgtc gtattgaaaa gttgggacag
     9721 gacaatgccg ccctggcaga gcaggtaaaa gccctgggtg ctaatcccgt cacggcgacc
     9781 ggtgagcctg taccgcagat gcctgcctca ccgcccggcc cggaaggcga accacagcca
     9841 ggaaacaccc ccgtatcctt cccgccgcag ggcagcgttg ctgttccacc accgacggcg
     9901 ttttatcccg ggaatggtgt cacgccacca ccacaggtga cgtaccagtc tgtgccggtg
     9961 cctaaccgga tacagcgtaa ggtgtttacc cgtaatgagg gaaaacaggg accatcactg
    10021 ccgtacattc cgtcaggaag ttttgcgaaa gccatgctga ttgaaggggc ggatgccaat
    10081 gcctctgtca ccggtaatga atccacggtg ccgatgcagc tgcgtatcac cggcctggtg
    10141 gaaatgccga acagcaagac gtatgacgca acgggatgtt ttgtgggtct ggaagcctgg
    10201 ggggatgtgt ccagtgagcg tgccattgta cgcacccgca atatcagttg cctgaaggac
    10261 ggcaaaacta ttgatatgcc gattaagggg catgtcagct tccggggtaa aaacggtatc
    10321 aagggcgaag tggtgatgct taacggcaaa atcctcggct gggcatgggg cgcgggattt
    10381 gttgacggta tcggtcaggg aatggagcgc gcctcccagc cggctgtcgg gctgggtgcc
    10441 acagccgctt acggggctgg tgatgtcctg aaaatgggta tcggtggcgg cgcatcgaaa
    10501 gccgcacaga cgctcagtga ctactacatc aaacgtgccg aacagtatca cccggtgata
    10561 ccgattggtg cgggcaacga agtgaccgtg gtgttccagg acggcttcca gctgaaaacc
    10621 gtggaagaga tggcgctgga acgcacgcag agcagagcgg aagaagacaa tccggaaagt
    10681 ccggttcctg ttccgccatc ggctgaaagt catcttaacg gctttaatac tgaccagatg
    10741 ctgaagcagc tgggcaacct gaatccgcag cagtttatgt ccggcagcca gggagggggc
    10801 aacgatggca aataatatgt cgtcccgtca ggcgtgccat gccgcccggt atgttgtcgc
    10861 ccgggttctg cgaggactgt tctggtgtct gaagtacacc gtcattctgc cactggccac
    10921 aatggccctg atggctctgt ttgttttatg gaaggacaac accacgccgg ggaaattact
    10981 ggttaaggag attaacttcg taagacaaac agcacctgcc ggacagttcc cggtcagtga
    11041 atgctggttt tcttcctctg attcttcagg cagatcagaa atacaggata tctgccatta
    11101 ccgcgcggct gatgctgcag attatgtcag ggagactgac cggtcactga tgcaactggt
    11161 caccgcatta tgggcaacac tggcactgat gtatgtctcg ctggcagcga tcaccgggaa
    11221 atatccggtg cgacccggaa aaatgaaatg tatccgggtg gtaaccgcag atgaacatct
    11281 gaaggaagtt tatacggaag acgcttccct gccgggaaaa atcaggaaat gccctgttta
    11341 tcttcctgat gacagaacaa acagaaacaa cggagataaa aatgaacatg cgtaatatta
    11401 atgttattac agccctctct gtgccgggta aaaccgtgtc agatgatttt atgcatgctg
    11461 ttctcagtaa ctgcgccaca agaatcgtac ttcctgcacc ggagaaattc ggttctgagt
    11521 cattgccgga caattttaat atgactgctg tcggtgtgat gaagaattca gaaatataag
    11581 gaacccttcg atgaataagc tggtttctga tggcagcgtc aaaaaaataa attatccggt
    11641 gctgtatgag tccggaataa cacctccgtt atgtgaagtc agtgcaccag aacctgatgc
    11701 gggtgggaaa cgcattgtgg catatgttta taaatcatca cggagtacgg tttttgaaaa
    11761 tcctgacatt gtaaaaacct gtacggtcag ggatttgaag aaggattttg tgaactgcga
    11821 tgagaaaggt gagggacaat gaaacagatt tctttcttta ttcctctgct ggggacctta
    11881 ttactttccg gctgtgccgg aaccagtacg gaatttgagt gtaacgccac cacatccgat
    11941 acctgtatga cgatggagca ggccaatgag aaggccaaaa aactggagca gtcctcagaa
    12001 gcaaagccgg ttgcggcatc actgccgcgc ctggctgaag ggaacttccg gacaatgccg
    12061 gtgcagaccg tcaccgcgac cactccgtcc ggcagcagac ctgcggtgac agcacatccg
    12121 gagcagaaac tgctggcacc tcgcccgctg tttaccgctg cccgggaagt gaaaacggtt
    12181 gttccggtca gttcagttac gccggtaaca cctcctcgtc cgctaagaac gggtgagcag
    12241 acggcagcat tatggatagc gccttatatt gataaccagg atgtttatca tcagccatcc
    12301 agcgtgtttt ttgttattaa accgtctgcg tggggaaaac cacgtattaa ttaactggcc
    12361 ctgaagttgt atatcagccg gcaatgccgg cgggctttct gtattcaaaa tctgcctgta
    12421 aaacgagtgc cctgtgcgtg aaaagggatg ggcggtagcg tgtcagaaca tgtcgggagg
    12481 aatattccgt gagtgatgaa gccgatgaag catattcagt gacagaacaa ctgaccatga
    12541 caggaataaa ccggatacgc cagaaaataa atgctcatgg tattcctgtt tatctctgtg
    12601 aagcatgcgg aaatcctatt ccggaagccc ggcggaaaat atttcccggt gtgacgttgt
    12661 gcgttgaatg tcaggcgtat caggaaagac agagaaaaca ttatgcataa gtcagtcgca
    12721 gaacatagtg atttaattcc ggatgaacat gagtggatat tcagaaaaca gaaatctttg
    12781 tatatgcgcc gggaaatggc gcgttaatta caggtattcc cttcatggct accgcatttc
    12841 tcgctttatt tttcaactaa ggaattcatg tgaataaccc acttgaggcc gtcactcagg
    12901 cggttaactc cctcgtcaca gcactgaaac tgcctgacga atccgcaaag gccaatgaag
    12961 ttctgggcga aatgagcttc ccgcagttca gccgtctgct gccgtaccgt gattacaacc
    13021 aggaatccgg tctgttcatg aatgacacca cgatgggctt tatgctggaa gccatcccca
    13081 tcaatggggc gaatgagtcc attgtggagg ccctcgatca catgctgcgc accaaactgc
    13141 cgcgcggtat tccgttgtgt atccatctga tgtccagtca gctggttggt gacaggattg
    13201 aatacgggct gcgtgagttc tcctggtcag gtgaacaggc tgaacggttt aacgccatta
    13261 cccgggccta ttatatgaaa gcggcagcga cacagtttcc gctgccggag gggatgaatc
    13321 tgcccctgac cctgcgccat taccgggtgt ttatctcgta ctgttctcct tcgaagaaaa
    13381 aaagccgggc cgacattctg gaaatggaaa acctggtgaa aatcatccgg gcgtcgttac
    13441 agggggccag tatcaccaca cagacggtgg atgcacaggc ctttatcgat attgtcgggg
    13501 agatgattaa ccataacccg gactccctgt acccgaaaag atgtcagctg gacccgtatt
    13561 ctgatctgaa ttatcagtgt gtggaggaca gttttgatct gaaagtccgg gctgattacc
    13621 tgacgctggg cctgcgtgag aacggcagga acagcacggc ccgcatcctg aatttccatc
    13681 tggcccgtaa cccggaaatc gccttcctgt ggaacgtggc cgacaactac agcaacctgc
    13741 tgaacccgga actgtccatc tcctgtccgt tcatcctgac gctgactctg gtggtggaag
    13801 accaggtgaa aacccacagc gaagccaacc tgaagtacat ggacctggag aaaaagtcga
    13861 agacctccta tgccaaatgg tttccgtccg tggagaaaga ggcgaaggag tggggggaac
    13921 tgcgtcagcg gctgggctcc ggtcagtcct ccgtggtgtc ctacttcctc aacatcacag
    13981 cattctgcaa ggacaataat gaaacggcgc tggaagtgga gcaggacatc ctgaacagct
    14041 ttcgtaaaaa cggttttgag ctgatttcac cgcgctttaa ccacatgcgc aatttcctga
    14101 cctgcctgcc ctttatggcc gggaaagggc tgtttaaaca gctgaaagag gccggagtgg
    14161 ttcagcgcgc agagagcttt aatgttgcca acctgatgcc gttagtggcg gataaccccc
    14221 tgacaccggc aggtctgctg gcacccacct accgtaacca gctggcgttt atcgatattt
    14281 tcttccgggg gatgaataac accaactaca acatggcggt ctgtggcacc tccggggccg
    14341 gtaaaaccgg gctgatacag ccacttatcc gcagcgtgct ggactccgga ggctttgccg
    14401 tggtgttcga catgggggat ggatacaagt ccctgtgtga gaacatgggc ggggtgtatc
    14461 tggacggtga aaccctgcgt tttaacccgt ttgcgaacat caccgatatt gaccagtcag
    14521 cggagcgtgt ccgtgaccag ttgtcagtga tggccagccc caacggtaac ctggatgaag
    14581 tgcatgaagg tctgctgttg caggcggtca gagcctcctg gctggccaaa gagaacagag
    14641 cacgtattga tgacgtggtg gatttcctga aaaacgccag tgacagcgag cagtatgccg
    14701 agtcaccgac tatccgcagc cgtctggacg aaatgattgt gctgcttgac cagtacactg
    14761 ccaacggcac ttacggccag tattttaact ctgatgagcc gtccctgcgg gatgacgcaa
    14821 aaatggtggt gctggagctg ggcggactgg aagaccgtcc gtcactgctg gttgcggtga
    14881 tgttctccct gattatctac atcgagaaca ggatgtaccg cacgccgcgt aacctcaaga
    14941 aactgaacgt tattgatgaa ggctggcgtc tgctggactt caaaaatcac aaggtcggtg
    15001 aatttattga gaaaggctac cgtacggccc gccgtcatac cggtgcctat atcaccatca
    15061 cacagaacat cgtcgacttt gactctgata aggcctccag tgctgcccgc gcggcatggg
    15121 gtaactcctc ctacaaaatt atcctcaaac agagtgcgaa ggagttcgcg aaatacaacc
    15181 aactgtatcc ggaccagttc ctgccactgc agcgcgacat gattggtaag tttggtgcgg
    15241 ccaaagacca gtggttcagt tccttcctgc tgcaggtgga aaaccattcc tcctggcacc
    15301 gtctgtttgt ggacccgtta agccgcgcca tgtacagctc tgacggcccg gattttgagt
    15361 ttgtgcagca gaagcgtaaa gaggggctga gtattcatga ggcagtgtgg cagctggcgt
    15421 ggaagaagtc agggccggaa atggcttcgc tggaagcctg gctggaagaa catgagaaat
    15481 acaggagtgt ggcatgagtt caacgcagaa acccgccgac gtcacggcag aacgacgcag
    15541 ccactggtgg tggacggtgc cgggatgcct ggcaatggtg ttactgaacg cagccgtcag
    15601 ttacggcatt gtcagactga acgcaccggt gactgtcgcc ttcaacatga aacagaccgt
    15661 ggatgcgttt tttgacagag ccagtcagaa acaactgtca gaagcgcagt caaaagccct
    15721 ttcagcgcgt tttaacacgg cactggaagc cagcctgcag gcgtggcagc agaaacacca
    15781 cgcggtcatt ctggtgtcgc ctgctgtggt acagggggca ccggatatca cccgggaaat
    15841 ccagcaggat attgcccggc gaatgagggc ggaaccatga gatgccgggg gctgattgcc
    15901 ctgctgatat gggggcagag tgtggccgcc gccgatcttg gtacctgggg cgatctgtgg
    15961 ccggtaaagg agccggacat gctgacggtg atcatgcagc gcctgacggc actggagcag
    16021 tccggtgaga tgggccggaa aatggatgcc tttaaggagc gggtgatccg caacagtctg
    16081 cggccccctg ccgtgcccgg tatcggacgc acggagaaat acggcagccg gttgtttgac
    16141 ccgtccgtca gactggctgc ggatatccgg gataacgaag ggcgggtgtt tgcccgtcag
    16201 ggtgaagtga tgaatccgct gcagtatgtt ccttttaacc agacgctgta tttcatcaat
    16261 ggcgatgatc cggcgcaggt ggcctggatg aaacgccaga cgccgcccac actggagagc
    16321 aaaattatcc tcgtgcaggg cagtatcccg gagatgcaga agtctctgga cagccgtgtt
    16381 tactttgacc agaacggtgt gctctgccag cgcctcggca ttgatcaggt cccggcacgg
    16441 gtgagcgccg ttcccggcga tcgcttcctg aaggtggaat ttattccggc agaggagggc
    16501 agaaaatgaa gcgaaggctg tggctgctga tgttattcct tttcgccggt catgtccctg
    16561 cggcgtctgc ggattctgcc tgtgaggggc gttttgtaaa cccgatcaca gatatctgct
    16621 ggagctgtat tttcccgctc tcgctgggca gtatcaaagt cagtcagggg aaggtccccg
    16681 acacggcgaa cccgtcgatg cccattcaga tttgtccggc actgccgccg ctgttcaggc
    16741 gtatcgggct ggccattggt tactgggagc cgatggcgtt gacggacgtc acccggtcac
    16801 cgggatgcat ggtgaacctg ggcttcagcc tgccggcttt tggtaaaacg gcacagggaa
    16861 cggcgaaaaa ggatgagaag caggtaaatg gggcgttcta tcacgttcac tggtacaaat
    16921 acccgctgac gtactggctg aacatcatca catcgctggg ctgtctggaa ggtggtgacc
    16981 tggatatcgc ttatctttct gaaatcgacc ccacctggac ggacagcagc ctgaccacca
    17041 ttctcaatcc ggaagctgtc atctttgcca atccgatagc acagggagcc tgcgcagcag
    17101 atgcgattgc cagcgccttt aatatgcctc tcgatgttct gttctggtgt gccggttcgc
    17161 agggaagtat gtacccgttc aatggctggg tgagtaatga gtccagtccg ttgcagtcct
    17221 ccctgctggt cagtgaacgc atggcgttca agctgcaccg tcagggcatg attatggaaa
    17281 ccatcggaaa aaataacgcc gtctgtaatg aatatccgtc cccaatcctg cccaaagaac
    17341 gctggcgtta ccagatggtg aatatgtatc cggacagcgg gcagtgccac ccgttcgggc
    17401 gcagcgtgac ccgctgggaa accgggaaaa atccgcccaa cacaaagaaa aacttcggct
    17461 acctgatgtg gcgtaaacgt aactgtgtct tcctgtgagg tgaatgatga agctgagtat
    17521 gaaatctctg gcagcactgc tgatgatgct gaacggggcg gttatggcgt cagaaaacgt
    17581 gaacactcct gaaaaccgcc agttcctgaa gcagcaggaa aatttaagca gacaactgcg
    17641 tgaaaaacct gaccatcagc tgaaagcctg ggcggagaaa caggtgctgg aaaaccccct
    17701 tcagcgttca gataaccatt tcctggatga gctggttcgt aaacagcagg cttcgcagga
    17761 cgggaaaccc cggcagggtg ctctgtattt tgtgtcgttt tccattcccg aagaggggct
    17821 gaaacgaatg ctgggcgaaa cccggcacta cggtattccg gccacactgc ggggcatggt
    17881 gaacaatgac ctgaagacca ccgctgaagc tgtgttgtcc ctggtgaaag acggcgcgac
    17941 tgatggtgtt cagatcgacc cgacgctgtt ttcacagtac ggcattcgca ctgtaccggc
    18001 actggtggtg ttctgcagtc agggatacga catcatccgg ggaaacctgc gggtcggcca
    18061 ggcgctggag aaagtggccg ccacgggtga ctgccggcag gtggctcatg atttactggc
    18121 agggaaagga gattccggga aatgaaacgt attttacctc tgatactggc tctggttgcc
    18181 ggcatggcac aggctgacag caacagtgat taccgggccg gttctgattt tgctcaccag
    18241 atcaaagggc agggaagcag cagtattcag ggctttaggc cacaggagag tatccccggc
    18301 tataacgcga atccggacga gacaaaatat tacggtggcg tgactgccgg cggggatggc
    18361 ggcctgaaaa atgacggcac cacggaatgg gcgaccggtg aaaccggaaa aaccattaca
    18421 gagtcattca tgaacaagcc gaaagacatt ctttcaccgg atgcaccgtt tatccagacc
    18481 ggcagggatg tggtgaaccg ggctgacagc attgtgggaa acaccgggca gcagtgcagt
    18541 gcgcaggaga ttagcaggag tgaatacacg aattacacct gtgagcggga tttacaggtg
    18601 gagcagtact gcacacgaac tgcccgtatg gagctgcagg ggagtaccac atgggaaacc
    18661 cggacgctgg agtatgaaat gagtcagcta cctgcacgtg aagtgaatgg tcagtatgtt
    18721 gtctccatta cctctcccgt taccggtgaa attgtcgatg cgcattacag ctggagtcgt
    18781 acttacttgc agaagagtgt acctatgaca attacagtac tgggaacccc actgagctgg
    18841 aatgccaaat actcagcaga tgcctcattt acaccagtac agaaaacact gactgccggt
    18901 gtggctttta cgtcatctca ccccgtccgg gtcgggaata caaaattcaa acgtcatacg
    18961 gcaatgaagc tgcgtctggt tgtcagggta aaaaaagcct cgtacacccc gtatgttgtc
    19021 tggtctgaaa gctgcccgtt cagcaaggag ctggggaaac tgacaaaaac agaatgtacg
    19081 gaggctggcg ggaacaggac gctggtgaaa gacggtcagt catacagcat gtaccagagc
    19141 tgctgggcat accgggacac gtatgtcacg cagtcagcag acaagggaac ctgtcagacc
    19201 tacaccgaca atcctgcctg taccctggtg tcacaccagt gtgcctttta ctccgaagaa
    19261 ggtgcctgtc tgcatgaata tgccacgtac tcctgtgagt caaaaacatc cgggaaagtg
    19321 atggtctgtg ggggagacgt attctgtctc gatggcgaat gcgataaggc tcagagcggg
    19381 cagagtaatg attttgccga agccgtttct cagctggcgg cactggccgc agcaggtaag
    19441 gatgttgcgg cgctgaacgg ggggggtgtc cgtgctttca ccggtcaggc gaaattttgt
    19501 aagaaggctg cagccggata cagcaactgc tgtaaggaca gcggctgggg acaggatatc
    19561 gggctggcca aatgcagcag tgatgaaaag gccctggcta aagcaaaatc aaacaaactg
    19621 accgtcagcg tcggggagtt ctgttcgaag aaagtgctgg gtgtctgtct ggagaaaaaa
    19681 cgcagctact gtcagtttga ttcgaagctg gcgcagatag tccagcagca ggggcgcaac
    19741 ggtcagttgc gtatcagttt tggtagtgcg aagcatcctg actgtcgggg gattacggtt
    19801 gatgagctgc agaaaattca gttcaacaga ctggatttca ctaacttcta cgaagacctg
    19861 atgaataacc agaaaatccc ggacagtggc gttctgacgc agaaagtgaa agagcagatt
    19921 gctgaccagc tgaaacaggc aggacagtaa ggtatgggaa ataaccgggg gaaatgatga
    19981 aagtcatatt cacgtcgaac cgttttattg attttcttat ccggcttttg attacagcga
    20041 ttgtcatttc tccggtaatt atctggtcgt gggatacggt aaaagaaacc acggcagacg
    20101 ggatgcttgc cgctgctttc gttatccttt actccggtgt gctcctgttt attctgtatt
    20161 tttgtttttc tgccctgact gacctgcaga aacctgatga aagaaaaagt gatgaaagga
    20221 atgaagatga ataaagcatt actgccactg ttactctgct gctttatttt tccggcgtca
    20281 ggaaaagatg caggctggca gtggtataac gagaaaataa atccgaagga aaaagaaaat
    20341 aaacctgtac ctgcagcccc ccgtcaggaa ccggatatta tgcagaaact ggccgcactg
    20401 cagacggcaa caaagcgggc gctgtacgaa gccattctgt atcccggcgt ggataatttt
    20461 gtgaaatatt tccggctgca aaattactgg actcagcagg ccgggctttt caccatgagc
    20521 gccagaaagg ccatgctggc acatcctgaa ctggactata acctgcagta cagccattac
    20581 aacggcacgg tacggaacca gctggcagca gaccaggcgc agcagcgaca ggccattgcg
    20641 aaactggctg aacactacgg catcatgttt ttttaccggg ggcaggaccc catcgacggg
    20701 cagctggcgc aggtcattaa tggcttccgg gatacctatg gtctgagtgt tattcccgtt
    20761 tccgtggatg gcgtgattaa tccgctgttg ccggattccc ggactgacca ggggcaggcg
    20821 cagcgcctcg gcgtgaaata tttcccggcc atgatgctgg ttgacccgaa acagggtagt
    20881 gttcgtccgt tatcatacgg ttttatttcg caggacgacc tggcaaaaca gttcctgaat
    20941 gtctctgagg attttaaacc gaatttttaa ccaaaggata tatatgcata caggggattt
    21001 gtgttttttt acaggtgcca gcctgtttat cgtgggggtt gttggttatt tctttacagg
    21061 actaaataat aaaggagttt atctactgag ctcgtttgtc ttctttgtag taaatgtcat
    21121 aagtgtatgt atgctgccag ataatttctt gtttctttgt ggtgcggtta tgaatcagtg
    21181 tgccgtaccg gttgtttcaa tggcagtcag caccatgccg attatcacga agtttgacag
    21241 tttcagaagg atgtttattt gtattatgtt gtcagccata tggtctggag tgatgtggtt
    21301 ttttattatt tcattagtga aatgactggt gctaatttgt cataaatgcc aaatccaata
    21361 gtgagattga ttaccacaga ccagaggata aaccagactg ctatccagtg acttctgaat
    21421 aaatcacaaa aataaacata gatgattaga aatagccata tcacaacagc gataattgct
    21481 ataaataaca gtatcgtcac aaataaatca gcaaaggttt taatggggag agtgtgcaac
    21541 aatgaataca ccagtaaagc aaaagccgca ttacctgata atgactctct tatgatgttt
    21601 ctcactattt ccagtttttc tttaaaagat cgcttttcca tttgtacctc tgactaatat
    21661 cacacaaacg cgaatattac agacatgaat actctcatgt aaataataac cggagtttaa
    21721 catgataagt aaacgcagat tctctttacc ccggcttgat attacgggaa tgtgggtatt
    21781 ttccctgggc gtctggtttc atatcgtcgc ccgtcttgtt cacagcaaac cctggatggc
    21841 tttttttctg gcggagctga ttgcggccat ccttgtgctg ttcggcgcat accaggtgct
    21901 ggatgcatgg attgcccgtg tcagccggga agagcgtgag gcactggaag ccaggcaaca
    21961 ggccatgatg gcagagcagc aggagggcgg acatgtctct cactaaatta ctgccggtta
    22021 ttctgttgat gatggccaca ggtgtgcagg cctccacccg ggatgaaatt gaacgactct
    22081 ggcatccgca gggtatggct gcgcagcctg cacaaccggc agcagacacg ccagccagga
    22141 cagacaagac agaaaagccg gctccccgct ggttccgcct cagcaacggc aggcaggtta
    22201 acctggccga ctggaaggtg gtgctgttta tgcaggggca ttgcccttac tgtcaccagt
    22261 ttgacccggt actgaagcag ctggcacagc agtacggctt ttccgttttt ccctacactc
    22321 tggatggtca gggggatatg gcctttccgg aagcattacc ggtgccaccg gacgtgatgc
    22381 agaccttctt cccgaatatc ccggtggcca caccgaccac cttcctggtc aacgtcaaca
    22441 cgcttgaggc attaccgctt ttacaggggg caacggatgc cgccggtttt atggcgcgga
    22501 tggataccgt tctgcagatg tacggaggga aaaaaggtgc gaaataagca ggtggtgtta
    22561 ctcattgccg gaatatccgg catcgcgacg ggaataatcg tcagcctgaa tattcccttt
    22621 atccgtcagg ggctttttta tcccgccagt cctgtagaaa tagtcgtttc gctgtgtctt
    22681 accttttctg tttctgttgt gttttttgtg gggcaattgt gggatggatt tcggtgtctg
    22741 aaatatatta cagccgcatg accggtctga atgaatcatc agtaatatca gaggaaactt
    22801 ataatgacaa aaaacaaaaa gaatcaggaa ttcaaaatca gaaaaattag acggaatatt
    22861 gagtatagtt tcagaggttc tgacagatat tttgatttgt ttattgtttt ccttgttgcc
    22921 ggaattgttt tatgggctgt tatgcacgtt attttcgatg tctgtattga ttcgtggatg
    22981 gccgacccga aattacttaa tttccagtat atgtggaatg ttctgatgaa agtcattccg
    23041 tttacgttat gggcgctggc agcagggttt cttgttacat tttttctgtc cccaatgtgc
    23101 gaattaatat tcggaaatat catgatattc ctgctgaaac gccgtatgcg ccgggagaac
    23161 acattaaggg agggcaagaa tgatgccacg cattaaacct cttctggttc tttgtgctgc
    23221 tttactgacg gtcacacccg cagcgtcagc ggatgtgaac agcgacatga atcagttctt
    23281 taacaagctg ggcttcgcct ccaataccac ccagccgggc gtctggcagg ggcaggccgc
    23341 cggctatgct tacggtggct ccctgtatgc ccgtactcag gttaaaaatg ttcatctgat
    23401 ttccatgacg ctgccggata tcaatgccgg atgtggcggc atcgacgcct atctcggctc
    23461 gttcagcttt attaatagcg agcagttgca gcgttttgtt aagcagatta tgagcaatgc
    23521 tgccggttac ttctttgacc ttgccctgca gacaacggtg ccggaaatca aaaccgcaaa
    23581 agacttcctg cagaaaatgg caagcgacat taacagtatg aacctcagtt cctgccaggc
    23641 ggcacagggg attatcggcg ggcttttccc ccggacgcag gtgtcccagc agaaagtctg
    23701 tcaggacatt gccggtgaga gcaatatttt tgctgactgg gctgcttccc ggcagggatg
    23761 taccgttggc gggaaatctg acagcgtcag ggataaagcc agcgacaagg ataaggagcg
    23821 ggtgaccaaa aacatcaaca tcatgtggaa tgcgctttcc aaaaacagaa tgtttgacgg
    23881 caacaaagag ctgaaagagt ttgtgatgac gctgaccggc tcactggtgt ttggtcccaa
    23941 cggcgaaatc acaccgctat cggccagaac cactgaccgc tcaattatcc gggccatgat
    24001 ggaaggcggt acagcaaaaa tttatcactg caacgattct gacaaatgcc tgaaagtggt
    24061 ggcagacaca ccggtgacca tcagccggga taatgcactg aagtctcaga ttactaaact
    24121 tctggccagc attcagaaca aggctgtcag tgacacgcct ctggatgaca aggaaaaagg
    24181 ctttatttcc agtaccacca tccccgtctt caaatacctg gttgacccgc agatgctcgg
    24241 tgtttccaac agtatgattt accagctgac ggactatatc ggttacgaca tcctgctgca
    24301 gtacattcag gagctgatac agcaggcccg ggcgatggtg gccacgggaa attatgacga
    24361 agcagttatc gaacatatta acgacaatat taatgatgcc acccggcaga ttgcggcgtt
    24421 tcagtcacag gtacaggtgc agcaggatgc gctgctggtc gtcgatcgtc agatgagcta
    24481 catgcgtcag cagctttccg cccgcatgct cagtcgttac cagaacaact atcacttcgg
    24541 agggagcacg ctgtgaatga agtttatgtg attgccggtg gtgaatggtt gcggaataac
    24601 ctgaacgcca ttgccgcctt tatgggaacc aggacgtggg attccattga aaaaattgct
    24661 ctcaccctgt ctgttgttgc ggtggccttt atgtgggtac agcgccataa cgtgatggat
    24721 ttgctgggct gggcggcggt gtttgtactt atcagcctgc tggttaatat ccgtacgtcg
    24781 gtgcagatta ttgataacag tgacctggtc aaagtccatc gggtggataa tgtgccggtc
    24841 ggactggcga tgccactttc actgacgacc cgtatcgggc atgcaatggt ggccagttac
    24901 gagatgatct acacgcaacc ggacagtttc acctacagca aaacggggat gctgtttggc
    24961 gcagaactgg tatcaaaaag caccgacttt ttgtcccgca atccggaaat cgccaatctt
    25021 tttcaggatt atgtgcagaa ctgtgtgatg ggggatattt acctgaacca caaatacacg
    25081 ctggaggagc tgatggcctc caatgatccc tacacgctga ttttttcccg ccccagtccg
    25141 ctgcggggcg tttatgacag caataataat ttcgtgacct gtaaggacgc gtcggtttcg
    25201 ctgaaagaca agctgaatct ggacacacag agtggcggaa aaacctggca ttattatgcc
    25261 cagcagttat ttggtggtcg ccctgatccg aacctgttgt tcagtacgct gattggcgac
    25321 agttaccgtt acttctatga ctcaagtaaa tcagccagcc agatcatccg ccagaatgtc
    25381 accattaatg cgctgaagga ggggatcacc agttatgcag cacgtaatgg tgactcagcc
    25441 agcctggtga atctggccac cacgtcatcg atggagaagc aacgtctggc acatgtctcc
    25501 atcggtcatg tggcgatgcg gacactgccc atgacgcaga ccatcctgac ggggatcgcc
    25561 atcggtattt tcccgctcct ggtactggcg gctgtcttca acaaactgac gctgtctgtc
    25621 ctgaaaggct atgtgtttgc cctgatgtgg ttgcagtcat ggccaatgtt gtacgccatt
    25681 ctgaacagcg ccatgacatt ttatgcgaag cagaatggtg caccggtggt gctctcggaa
    25741 atttcacaga tacagctgaa atactccgat ctggcttcca ctgccgggta tctttccatg
    25801 atgatcccgc cattatcctg gatgatggtc aggggactcg gggccggatt ttccagtgtg
    25861 tacagccatt tcgcttcctc tgctatcagc ccgaccgcca gtgcggcagg cagtgtggtt
    25921 gacggtaatt actcctacgg caacatgcag acggaaaacg tgaacggctt cagctggagc
    25981 accaacagca ccacgtcgtt tggtcagatg atgtaccaga ccggcagtgg tgcaaccacc
    26041 acacagaccc gtgacggtaa tatggtgatg gatgcaagcg gagcgatgtc ccggttaccg
    26101 gttggtatca atgcaacgcg tcagattgca gcggcacaac aggaaatggc ccgggaggca
    26161 tcgaacagag cagaaagcgc cctgcatggg ttcagcagca gtattgccag tgcctggaac
    26221 tcgctcagtc agtttggttc taaccggggg agcagtgatt ctgtcacagg tggtgctgac
    26281 agcacgatga gcgcacagga ttccatgatg gccagccgta tgcgcagtgc agtggaaagc
    26341 tatgcgaagg cgcataatat cagtaatgag caggcgactc aggaactggc atcaacaagt
    26401 accaggctat ctggtggaat gtatgctgat gctcatgctg aatggggggt taaacctaaa
    26461 attcttggtg ttggtggtgg ggtaggcatc agaggtggat ttaaggggag cttggatgca
    26521 acggatgatg actcacattc agcaagtagt ggcagcaggg ctacccatga tgctcgccat
    26581 gatatcgatg ccagagctac acaagacttt aaagaggcca gcgattactt taccagtcgc
    26641 aaagtcagtg aatccggcag ccatactgac aataatgctg attcccgtgt ggaccagctg
    26701 tctgcagccc tgaattcagc gaaacagagt tacgatcagt acacgacgaa tatgacccgc
    26761 agccatgaat atgctgaaat ggcatcccgt actgaaagca tgagtgggca gatgagtgaa
    26821 gatctgtcgc aacagtttgc acagtatgtg atgaaacacg caccgcagga tgccgaagct
    26881 attctgacaa acaccagttc accggagatc gcagaacgcc gtcgggcgat ggcatggtct
    26941 tttgttcagg aacaggtgca gcctggtgtt gataatgcct ggcgtgaatc ccgtggggat
    27001 attggtaaag gaatggagag cgtaccttcg ggtggtggca gccaggatat tattgctgac
    27061 catcaggggc atcaggccat tattgatcaa agaacgcagg acagtaatat ccgtaatgat
    27121 gtaaaacatc aggttgataa tatggtcaca gaatataaag ggaatatcgg agatactcag
    27181 aatagtattc atggcgaaga aaatattgta gacagacaat attcagagtt aaaaaataat
    27241 cacaaacagg aagaaattca acaaaacaac agatataatg aagaaaataa acgacagaaa
    27301 ttaataccaa caccgtctga agatgcgtta aaacagatgg tggatgataa gaaagaacga
    27361 ttgaaggggc cattatgatc actcactatg atataaaaat ggagatgcaa aaactaaagg
    27421 aggtactctc tgtagagggt gttaatatcc catcattatt acaagtcata aagccgggaa
    27481 cttatgtgtt tttatgggtt ttattatggc caacttttct gcgtttagta tcggttaaaa
    27541 gtgatgtcag ggatgttggc tttgatatat gtgctagtgg aatgatgggg ttcctgcttt
    27601 ttgtggctat tacaaatgga atgatgttat accttgcgat tcctgatagt ttcagaaagg
    27661 attcaaaaat aataaatttt atgtattcta agagtaagac atatattttg ttgtttttga
    27721 ttgttttttt ctatggtttc gtttatgcat tctatcttat atgtttttgc actaatgatt
    27781 acattcatat tatttttctt ggtgtatacc atagatataa atcgttataa tctcttagca
    27841 atagtctcag taataggact gttcaaaaaa gagtctgtta gttaaaagga tattttggat
    27901 gaaaacaaaa aaattgatga tggttgcact ggtcagttcc actctggccc tttcagggtg
    27961 tggtgcgatg agcacagcaa tcaagaagcg taaccttgag gtgaagactc agatgagtga
    28021 gaccatctgg cttgaacccg ccagcgaacg cacggtattt ctgcagatca aaaacacgtc
    28081 tgataaagac atgagtgggc tgcagggcaa aattgctgat gctgtgaaag caaaagggta
    28141 tcaggtggtg acttctccgg ataaagccta ctactggatt caggcgaatg tgctgaaggc
    28201 cgataagatg gatctgcggg agtctcaggg atggctgaac cgtggttatg aaggcgcagc
    28261 agttggtgca gcgttaggtg ccggtatcac cggatataat tccagttctg ccggtgccac
    28321 actcggtgtg ggccttgctg ccggtctggt gggtatggct gcagatgcga tggtggaaga
    28381 tgtgaactat accatgatca cggatgtgca gattgcagag cgtactaagg caacggtgac
    28441 aacggataat gttgccgccc tgcgtcaggg cacatcaggt gcgaaaattc agaccagtac
    28501 tgaaacaggt aaccagcata aataccagac ccgtgtggtc tcaaatgcga acaaggttaa
    28561 cctgaaattt gaagaggcga agcctgttct cgaagaccag ctggccaaat caatcgcaaa
    28621 tattctctga ttatcttccg gaggctggtc tgaccggcct cctgactgac gcctcgcttt
    28681 gctcgttgtc caaccccgga aagaaataaa ataaatttta tttctccccg gcgtttccga
    28741 aataaatatg aaaacactga gcggttgtgc aaattctttg tgcgaccgtg aagtgttgcc
    28801 ggcgaagccg gaatttaacg gttattaatc ttttcatcat taataatcag tccgactgac
    28861 ttttttcttc ggaatatcat catgagtttt aacgcaaagg atatgaccca gggcggtcag
    28921 attgcgtcca tgcgtatccg catgttcagc cagatcgcca atatcatgct ttactgcctg
    28981 tttatttttt tctggatact cgttggtctg gttttatggg taaaaataag ctggcagacg
    29041 tttgtgaacg gctgtattta ctggtggtgt accacgctgg aaggcatgcg ggatttaatc
    29101 aagtcccagc cggtatatga gatccagtat tacggcaaaa ccttccggat gaacgctgct
    29161 caggtactgc atgataaata tatgatttgg tgcggagagc agctatggtc cgcattcgtt
    29221 ctggccacag ttgtggcact ggttatttgc ctgattacct tctttgttgt ctcctggatt
    29281 ctggggcgtc agggtaaaca acagagcgaa aatgaagtca caggtggtcg tcagctgaca
    29341 gacaatccga aagacgttgc ccggatgctg aaaaaagacg acaaggactc cgatatccgg
    29401 attggcgacc tgccgattat ccgggattct gaaatccaga acttctgtct gcacggcacg
    29461 gtcggggccg gtaagtcgga agttatccgt cgtctggcca actacgcccg taagcgcggt
    29521 gatatggtgg tgatttatga ccgttcaggg gaatttgtta aaagttacta tgatccctcc
    29581 atcgataaaa tcttgaatcc gctggatgcc cgctgtgccg catgggattt atggaaggag
    29641 tgtctgacac agccggattt tgataatacg gcaaataccc tgatcccgat gggcacaaaa
    29701 gaggacccgt tctggcaggg ttcaggacgt accatttttg cggaagcggc gtacctgatg
    29761 cgtaatgacc ccaaccgcag ctacagcaaa ctggtggaca ctctgctttc catcaaaatc
    29821 gaaaaactgc gtaccttcct gcgtaattca ccggcggcca acctggtgga agagaaaatc
    29881 gagaaaacgg cgatttccat ccgtgctgtg ctgaccaact acgtgaaagc catccgttac
    29941 ctgcagggga ttgagcataa cggtgagccc ttcaccatcc gtgactggat gcgtggtgtc
    30001 cgggaagatc agaaaaacgg ctggctgttt atctcatcga acgccgacac ccatgcctcc
    30061 ctgaagccag tgatctccat gtggctgtcc attgccattc gtggtctgct ggcaatggga
    30121 gaaaaccgta accgtcgtgt gtggtttttc tgtgacgagt tacccacgtt acacaaactg
    30181 cctgacctgg tggagatcct gccggaagcc cgtaagttcg gtggctgtta tgtgtttggt
    30241 atccagtcct atgcccagct ggaagatatc tacggtgaga aagcggctgc cacgttgttt
    30301 gacgtcatga acacccgtgc ctttttccgt tctcccagcc ataagattgc agagttcgct
    30361 gccggtgaga ttggtgagaa agagcacctg aaagccagcg agcagtattc ctacggtgct
    30421 gatccggtac gtgacggggt atcgaccggt aaggatatgg agcgccagac gctggtcagt
    30481 tattccgaca ttcagtctct gccggatctg acctgttatg tcaccctgcc cggaccgtat
    30541 ccggcagtaa aactctctct gaaatatcag acacgaccga aggtcgctcc ggagtttatt
    30601 ccgcgtgaca tcaacccgga aatggagaac cgcctgagtg ccgtacttgc cgcaagggaa
    30661 gcagaaggtc gtcagatagc cagcctcttc gaaccggatg tcccggaggt tgtttccgga
    30721 gaagacgtga ctcaggctga acagccgcaa cagccgcaac agccgcaaca gccgcaacag
    30781 ccggtgtctc ctgccatcaa cgataagaag tcagattcag gtgtgaatgt tccggcaggg
    30841 gggatcgagc aggagctgaa aatgaaaccg gaagaagaga tggaacagca actgccaccc
    30901 gggatcagtg aatccggtga agtggtggat atggccgctt atgaggcatg gcaacaggaa
    30961 aatcatccgg acacccagca gcagatgcag cgtcgtgaag aggtgaacat taatgtgcac
    31021 cgggagcgcg gggaggatgt tgagccggga gatgatttct gatgatgagt atcgcacagg
    31081 tcagatcggc cggaagtgcc ggtaactatt ataccgacaa ggataattac tatgtactgg
    31141 gcagcatggg agaacgctgg gccggcaggg gggctgaaca gctgggactg cagggcagtg
    31201 tcgataagga tgtttttacc cgtcttctgg agggaaggct gccggacgga gcggatctaa
    31261 gccgcatgca ggatggcagt aataagcatc gtcccggcta cgacctgacc ttctccgccc
    31321 ccaaaagtgt ctccatgatg gccatgttag gtggcgataa gcgcctgatt gatgcacata
    31381 accaggccgt ggactttgct gttcgtcagg tggaggcgct ggcctccaca cgggtgatga
    31441 cggacggaca gtcagaaacg gtactgaccg gtaatctggt gatggcactg tttaaccacg
    31501 acaccagtcg cgatcaggaa ccacagttac acacgcatgc ggtggtagct aatgtcacgc
    31561 agcataacgg tgagtggaag acactgagca gtgacaaagt ggggaaaacg gggttcattg
    31621 agaatgtgta cgctaatcag attgcctttg gcaggctcta ccgggaaaaa ctgaaagagc
    31681 aggttgaggc gctgggctat gaaacggaag tggtgggtaa gcacggtatg tgggaaatgc
    31741 cgggcgtacc ggtggaggcc ttttccggac gctcacagac tatccgggag accgtcgggg
    31801 aggacgcctc gctgaaatcc cgggatgtgg cggcgctgga tacgcgtaaa tccaaacagc
    31861 acgtcgatcc tgaaatcaaa atgaccgagt ggatgcagac gctgaaggaa accgggttcg
    31921 atatccgggc gtatcgtgac gcagcggaac aacgggcata tacccgcacg cagacacccg
    31981 gaccagcttc acaggacggg ccggatgtgc agcaggcggt gacacaggcg attgccggat
    32041 taagtgaacg caaagtgcag tttacgtaca cggacgtgct ggccaggacg gtcggcatac
    32101 tgccgccgga agccggtgtg attgagcggg cgcgcgccgg tatcgatgag gccatcagcc
    32161 gtgagcaact catccccctt gaccgtgaga aggggctgtt cacatcagga attcatgtgc
    32221 tcgatgagct gtcagtccgg gcactcagtc gtgacatcat gaaacagaac cgggtgaccg
    32281 tacatccgga gaaaagtgtc ccccggacgg ccggttacag cgatgcggtc agtgttctgg
    32341 cacaggatcg cccgtcgctg gctattgtgt ccgggcaggg cggtgcagcc gggcagcgtg
    32401 agcgggtggc tgaactggtc atgatggccc gggagcaggg gcgggaggtg cagattatcg
    32461 ctgctgaccg tcgctcgcag atgaacctga agcaggatga acggctgtcc ggtgagctga
    32521 taaccggacg tcgtcagctg ctggaaggca tggccttcac gccgggcagt actgttatcg
    32581 ttgaccaggg cgaaaaactc tccctgaaag agacgttaac cctgctggac ggtgccgcac
    32641 gtcataacgt acaggtcctg ataaccgaca gcgggcagcg aaccggtaca ggcagtgcgc
    32701 tgatggccat gaaggatgcc ggggtgaaca catatcgctg gcagggggga gaacagcgac
    32761 cggccaccat catcagtgaa ccggaccgta atgtccgcta tgcccggctg gccggagatt
    32821 ttgcggccag cgtgaaagcc ggagaagaga gcgtggcaca ggtcagcgga gtacgggaac
    32881 aggccatact gacacaggcc attcgcagtg agctgaaaac acagggcgtg ctcggacacc
    32941 cggaggtaac catgaccgcc ctgtcaccgg tctggctgga cagccggagc cgttacctgc
    33001 gggatatgta ccgaccgggg atggtgatgg agcagtggaa cccggagaca cgcagtcatg
    33061 accgctatgt gatagaccgg gtgacggcgc agagtcacag cctgaccctg cgggatgcgc
    33121 agggtgaaac gcaggtggtg cgtatttctt ctctggacag cagctggtcg ctgttccggc
    33181 cggaaaaaat gccggtggca gacggcgagc gtctgagggt gacagggaaa attcccggac
    33241 tccgcgtctc cggcggtgac cgcctgcagg tgacatccgt cagtgaagat gcgatgacgg
    33301 ttgttgtgcc gggacgtgct gaaccggcca ccctgcctgt gagcgattca ccgttcacgg
    33361 cactgaagct ggagaacggc tgggtggaaa cgcccgggca ttccgtcagc gacagtgcga
    33421 cggtttttgc ctccgtcaca cagatggcaa tggacaatgc caccctgaac ggtctggccc
    33481 gcagtggtcg tgatgtccgg ctgtattcct cactggatga aacccgtact gcggaaaaac
    33541 ttgcccgcca tccgtccttt acggtggttt ctgagcagat aaaggcgcgt gccggtgaga
    33601 catcgctgga aacggctatc agtcatcaga agtccgcact tcacacgccg gcacagcagg
    33661 ccattcatct ggcccttccg gtggtggaaa gtaaaaacct ggccttcagc catgtggacc
    33721 tgctgacaga ggcaaagtcg tttgctgcag aaggaaccag ttttactgaa ctggggcggg
    33781 aaatcgatgc gcagataaaa cggggtgatt tactgcatgt ggatgtggct aaaggctatg
    33841 gcacagacct gctggtttcc cgtgcgtcgt atgaggcaga aaagagcatt cttcgccata
    33901 ttctcgaggg taaggaggcg gtcacgccgc tgatggagag agtacctggc gaactcatgg
    33961 agaaactgac atcaggacag cgtgccgcca cccgcatgat actggaaacg tccgaccgtt
    34021 tcacggtggt gcaggggtat gccggggtgg gtaagaccac acagttccgg gcggtgatgt
    34081 cagccgtgaa catgctgccg gagagtgagc gtccccgtgt cgttgggctg gggcccacgc
    34141 accgtgcggt cggggagatg cgcagcgccg gcgtggatgc acagacactg gcgtcctttc
    34201 tgcatgacac gcagctgcag cagcgcagcg gagaaacgcc ggatttcagc aacacgctgt
    34261 tcctgctcga tgagagctca atggtgggca ataccgacat ggcacgggca tacgccctga
    34321 ttgcggccgg tggcggtcgt gctgtggcca gcggtgacac ggaccagctg caggccatcg
    34381 cgcccggtca gcctttccgt ctccagcaga cgcgcagtgc tgccgatgtg gccatcatga
    34441 aggagattgt gcgtcagacg ccggaactgc gggaggcggt atacagcctg attaaccggg
    34501 atgtggaaaa ggcactgtcc gggcttgaga gtgtgaaacc gtctcaggtg ccacgtctgg
    34561 agggcgcatg ggcaccggag cactccgtga cggagttcag tcacagccag gaagcgaaac
    34621 tggcagaagc gcagcagaag gcgatgctga aaggcgaggc tttcccggat atccccatga
    34681 cactgtatga agccattgtc cgcgactata ccggcaggac accggaagca cgggagcaga
    34741 cgctgattgt cacgcacctg aatgaggacc agcgcgtact gaacagcatg attcatgatg
    34801 cacgggaaaa ggccggtgag ctggggaaag agcaggtcat ggtgcctgtc ctgaatacag
    34861 cgaatatacg tgacggggag ctgcgtcgtc tctccacctg ggagacacat cgggacgcac
    34921 ttgccctggt ggataatgtg tatcaccgga ttgccggtat cagcaaggat gacgggctga
    34981 taaccctgca ggatgcggag ggtaacacgc ggctgatttc gccccgggag gcggtggctg
    35041 aaggtgtcac actgtacaca ccagacaaaa tccgggtggg gaccggcgac aggatgcgct
    35101 tcacgaagag tgaccgggag cgcggttatg tggccaacag cgtctggacg gtgacagcgg
    35161 tttccggtga cagtgtcacg ctgtcggacg gacagcagac ccgggtgatt cgccccggtc
    35221 aggagcgggc agagcaacat attgacctgg cctatgccat cactgcccac ggtgcgcagg
    35281 gggcgagtga aacctttgcc atcgcgcttg aaggcacgga aggtaaccgg aaacagatgg
    35341 ccggctttga gtcagcctac gtggccctgt cgcgtatgaa gcagcatgtg caggtgtaca
    35401 ccgataaccg tcagggctgg acggatgcca ttaacaatgc cgtacagaaa ggaactgccc
    35461 acgatgtgct ggagccgaaa ccggaccggg aggtcatgaa tgcgcagcgg ctgttcagta
    35521 cggcacggga actgcgggac gtggcggcag gccgtgccgt tctccgtcag gcggggctgg
    35581 ccgggggaga cagtcctgca cggtttattg ctccgggacg taaatatccg caaccgtatg
    35641 tggcactgcc ggcttttgac cgtaacggca ggtccgccgg tatctggctg aacccgctga
    35701 ccacggatga cggaaacggg ctgcggggat tcagcggtga aggccgtgtg aagggcagcg
    35761 gggatgcgca gttcgtggcc ctgcagggca gccgtaacgg agagagcctg ctggctgata
    35821 atatgcagga tggcgtccgg attgcccgtg ataatcccga cagtggtgtg gtggtaagaa
    35881 tcgccggtga aggccgtccg tggaatcccg gtgccatcac cggtggccgc gtgtgggggg
    35941 atattccgga taacagcgtc cagccgggag ccggaaatgg tgaatcggtc acggcagagg
    36001 tactggcaca gcggcaggct gaagaggcca tccgccgtga aacggaacgc cgcgcagatg
    36061 aaattgtcag gaaaatggta gagaacaaac ctgacttgcc ggacgacaaa acagagctgg
    36121 ctgtcaggga tattgccggg caggaacgtg accggactgc cacttctgaa cgggaaaccg
    36181 cactgccgga gagtgtgctg cgtgaatcac aacgggaacg ggaagcggtc cgggaggttg
    36241 cccgggaaaa tctgctgcag aggcttctgc agcagatgga gcgggatatg gttcgtgacc
    36301 tgcagaaaga gaaaaccctg ggcggagact gatacaggaa gacaaacact gatgacaacg
    36361 gataacacga acacgatacg taacgattca ctggctgcac ggaccgatac ctggttgcag
    36421 tcatttctgg tctggtcacc cggacagcgg gatatcatca aaacggtggc actggtgctg
    36481 atggtactgg accacatcaa tctgatattc cagctgaagc aggaatggat gtttctggtc
    36541 gggcgtgggg cctttccgct ttttgccctg gtgtgggggc tgaatctgtc ccgtcatgcg
    36601 catatccggc aaccggccat taaccggctg tggggatggg gaattattgc ccagttcgca
    36661 tattatctgg caggctttcc ctggtatgag gggcatatcc tgtttgcctt tgcagtggtg
    36721 gcacaggtgc tgacgtggtg tgaaacgcgc agtgggtggc gtacagcagc ggccattctc
    36781 ctgatggccc agtgggggcc tttgtccggc accagttacg gcattgccgg gctgctgatg
    36841 ctggcagtca gccaccggct gtaccgggcg gaagacagag cggaacgtct ggcgctggtc
    36901 gcctgcctgc tggctgttat tccggcgctt aaccttgcca ccagtgatgc agcggcggtg
    36961 gctggtcttg tgatgacggt gctgaccgtt ggtctggtgt cgtgtgcagg aaaatcatta
    37021 ccccgtttct ggcccggaga ctttttcccg acgttctatg cctgtcatct ggctgtgctg
    37081 ggcgttctgg cgctgtgacg ggtgtggtat ctttggccgc aagaggatga ttcgtcagag
    37141 gcagaacaca gcatgacaga gcagaagcga ccggtactga cactgaagcg gaagacagag
    37201 ggaacagcgc ctgtccgcag ccggaaaacc atcatcaatg tcaccacgcc accaaaatgg
    37261 aaggtgaaaa agcagaaact ggccgagaaa gcggcccggg aagcagagct ggcggcaaaa
    37321 aaagcgcagg ccagacaggc gctgtccatt tatctgaacc tgccctcact ggatgaggcc
    37381 gtgaataccc tgaagccctg gtggccggga ttatttgacg gtgacacgcc ccggcttctg
    37441 gcctgcggta tccgggacgt gttactggaa gacgtggcgc agcggaatat cccgctctcg
    37501 cataaaaaac tgcgcagggc gctgaaggcc atcacccgtt cagaaagcta tctgtgtgcc
    37561 atgaaagccg gtgcctgccg gtatgacacg gaagggtatg tgacggagca tatttctcag
    37621 gaggaggaaa cgtatgcggc agagcgtctg gataaaatcc gccgccagaa ccggataaag
    37681 gcagaacttc aggccgtgct tgatgagaaa taaaaaaagc ctccctcaga gagaggaggc
    37741 agggaaataa ggcttaaaag gaaataactt ccgtacccga aaggaagcca attcagtaga
    37801 ttatttaaca ccataatact gacgggttaa agaggagtga taaagatgaa tggattcaga
    37861 aacagttcac ggaacggtca ggtctggtgc tggcagcgtg ccggaagccg ggccgttatt
    37921 ctggaggtca gtggacgctg gatggaagcg gcagaaggat ggcgacgggc tgcctgtgtt
    37981 gcgccccgga cagactggca gcagtttgcc cgaaaaaggg ctgaacactg ccaccggcgc
    38041 tgccggggaa gggtgtaacg aaaaaagcag ccttcattac tccagggatt cagaaggctg
    38101 aataatgcat gagatttgct ttttttaata tccggtcggg cagtatgacc ggacagttct
    38161 gagtagcaca gagttttttc cgtattaagt cgtgatttta tattttgtga ttaatttcac
    38221 aaaataaggt gttattcagt gtgtgctgca atattcagga tgcctgaaat acaggtgcta
    38281 tttatctgat atggagaata acatgaggaa atatattcca ctggtattat ttatctttt
//
LOCUS       DACAOP010000037        38300 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.037, whole genome shotgun sequence.
ACCESSION   DACAOP010000037 DACAOP010000000
VERSION     DACAOP010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38300
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.037"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(124..429)
                     /locus_tag="IT892_002116"
     CDS             complement(124..429)
                     /locus_tag="IT892_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HAP3135334.1"
                     /translation="MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTES
                     EKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA"
     gene            complement(537..613)
                     /locus_tag="IT892_002117"
     tRNA            complement(537..613)
                     /locus_tag="IT892_002117"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(577..579),aa:Val,seq:gac)
     gene            complement(618..694)
                     /locus_tag="IT892_002118"
     tRNA            complement(618..694)
                     /locus_tag="IT892_002118"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(658..660),aa:Val,seq:gac)
     gene            1002..2258
                     /locus_tag="IT892_002119"
     CDS             1002..2258
                     /locus_tag="IT892_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135335.1"
                     /translation="MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENT
                     VVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRH
                     PEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGE
                     LLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGT
                     DGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRA
                     PVELTGSVALLDGASMIIGYGAELQQSTITVQQGGVLILDGSTVKGDSVTFIVGNINL
                     NGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITD
                     ASRQTLCNALKLQPDEDGIGATLQPA"
     gene            complement(2299..3672)
                     /gene="mdtK"
                     /locus_tag="IT892_002120"
     CDS             complement(2299..3672)
                     /gene="mdtK"
                     /locus_tag="IT892_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MdtK"
                     /protein_id="HAP3135336.1"
                     /translation="MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDM
                     AAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLI
                     MLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPG
                     MVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSM
                     RDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI
                     ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTV
                     SLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITF
                     TAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAI
                     ILQRASR"
     gene            3887..4528
                     /gene="ribE"
                     /locus_tag="IT892_002121"
     CDS             3887..4528
                     /gene="ribE"
                     /locus_tag="IT892_002121"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HAP3135337.1"
                     /translation="MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAH
                     NGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGH
                     IMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVH
                     LIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA"
     gene            complement(4568..5716)
                     /gene="cfa"
                     /locus_tag="IT892_002122"
     CDS             complement(4568..5716)
                     /gene="cfa"
                     /locus_tag="IT892_002122"
                     /EC_number="2.1.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane fatty acyl phospholipid synthase"
                     /protein_id="HAP3135338.1"
                     /translation="MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNP
                     DFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGAR
                     LFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMIC
                     EKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTIL
                     LQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLN
                     VDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPE
                     IADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR"
     gene            complement(6007..7218)
                     /locus_tag="IT892_002123"
     CDS             complement(6007..7218)
                     /locus_tag="IT892_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HAP3135339.1"
                     /translation="MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVS
                     ASLSLFLAGFAAAQLLWGPLSDRYGRKLVLLIGLTIFALGSLGMLWVENAATLLVLRF
                     VQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQ
                     AIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSAS
                     FFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLV
                     LFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAA
                     LQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNH
                     GNAEVAHSESH"
     gene            7331..8263
                     /locus_tag="IT892_002124"
     CDS             7331..8263
                     /locus_tag="IT892_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3135340.1"
                     /translation="MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWL
                     AVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIV
                     RPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
                     RDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKR
                     VVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQND
                     MSPALTWLLEYLGDSETLNKEWLREPEETPATGD"
     gene            complement(8260..9285)
                     /gene="purR"
                     /locus_tag="IT892_002125"
     CDS             complement(8260..9285)
                     /gene="purR"
                     /locus_tag="IT892_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor PurR"
                     /protein_id="HAP3135341.1"
                     /translation="MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELH
                     YSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLE
                     KQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVID
                     NAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQ
                     GDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDN
                     VRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADG
                     PFRDYRR"
     gene            9584..9673
                     /gene="ynhF"
                     /locus_tag="IT892_002126"
     CDS             9584..9673
                     /gene="ynhF"
                     /locus_tag="IT892_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein YnhF"
                     /protein_id="HAP3135342.1"
                     /translation="MSTDLKFSLVTTIIVLGLIVAVGLTAALH"
     gene            9839..11008
                     /locus_tag="IT892_002127"
     CDS             9839..11008
                     /locus_tag="IT892_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3135343.1"
                     /translation="MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGM
                     LISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRIL
                     TSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
                     SFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMF
                     TLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLL
                     MVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAF
                     NLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS"
     gene            complement(11243..11824)
                     /gene="sodB"
                     /locus_tag="IT892_002128"
     CDS             complement(11243..11824)
                     /gene="sodB"
                     /locus_tag="IT892_002128"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Fe]"
                     /protein_id="HAP3135344.1"
                     /translation="MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIK
                     GTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFG
                     SFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWE
                     HAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA"
     gene            complement(11952..12767)
                     /locus_tag="IT892_002129"
     CDS             complement(11952..12767)
                     /locus_tag="IT892_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAP3135345.1"
                     /translation="MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKA
                     DKKKSTATTKKTQKTAKKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNKTASA
                     SFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPYRWGG
                     SSPSTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRTQG
                     RGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR"
     gene            13101..13448
                     /gene="grxD"
                     /locus_tag="IT892_002130"
     CDS             13101..13448
                     /gene="grxD"
                     /locus_tag="IT892_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monothiol glutaredoxin 4"
                     /protein_id="HAP3135346.1"
                     /translation="MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALAACG
                     ERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGELVGGCDIMIEMYQRGELQQLIKE
                     TAAKYKSEEPDAE"
     gene            complement(13499..18115)
                     /locus_tag="IT892_002131"
     CDS             complement(13499..18115)
                     /locus_tag="IT892_002131"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP3135347.1"
                     /translation="MADNPDPSSLLPDVFSPATRDWFLRAFKQPTAVQPQTWHVAARS
                     EHALVIAPTGSGKTLAAFLYALDRLFREGGEDTREAHKRKTSRILYISPIKALGTDVQ
                     RNLQIPLKGIADERRRRGETEVNLRVGIRTGDTPAQERSKLTRNPPDILITTPESLYL
                     MLTSRARETLRGVETVIIDEVHAVAGSKRGAHLALSLERLDALLHTSAQRIGLSATVR
                     SASDVAAFLGGDRPVTVVNPPAMRHPQIRIVVPVANMDDVSSVASGTGEDSHAGREGS
                     IWPYIETGILDEVLRHRSTIVFTNSRGLAEKLTARLNELYAARLQRSPSIAVDAAHFE
                     STSGATSNRVQSSDVFIARSHHGSVSKEQRAITEQALKSGELRCVVATSSLELGIDMG
                     AVDLVIQVATPLSVASGLQRIGRAGHQVGGVSKGLFFPRTRRDLVDSAVIVECMFAGR
                     LENLTPPHNPLDVLAQQTVAAAAMDALQVDEWYSRVRRAAPWKDLPRRVFDATLDMLS
                     GRYPSGDFSAFRPKLVWNRETGILTARPGAQLLAVTSGGTIPDRGMYSVLLPEGEEKA
                     GSRRVGELDEEMVYESRVNDIITLGATSWRIQQITRDQVIVTPAPGRSARLPFWRGEG
                     NGRPAELGEMIGDFLHLLADGAFFSGTIPPWLAEENTIANIQGLIEEQRNATGIVPGS
                     RHLVLERCRDEIGDWRIILHSPYGRRVHEPWAVAIAGRIHALWGADASVVASDDGIVA
                     RIPDTDGKLPDAAIFLFEPEKLLQIVREAVGSSALFAARFRECAARALLMPGRTPGHR
                     TPLWQQRLRASQLLEIAQGYPDFPVILETLRECLQDVYDLPALERLMRRLNGGEIQIS
                     DVTTTTPSPFATSLLFGYVAEFMYQSDAPLAERRASVLSLDSELLRNLLGQVDPGELL
                     DPQVIRQVEEELQRLAPGRRAKGEEGLFDLLRELGPMTVEDLAQRHTGSSEEVASYLE
                     NLLAVKRIFPAMISGQERLACMDDAARLRDALGVRLPESLPEIYLHRVSYPLRDLFLR
                     YLRAHALVTAEQLAHEFSLGIAIVEEQLQQLREQGLVMNLQQDIWVSDEVFRRLRLRS
                     LQAAREATRPVAATTYARLLLERQGVLPATDGSPALFASTSPGVYEGVDGVMRVIEQL
                     AGVGLPASLWESQILPARVRDYSSEMLDELLATGAVIWSGQKKLGEDDGLVALHLQEY
                     AAESFTPAEADQANRSALQQAIVAVLADGGAWFAQQISQRIRDKIGESVDLSALQEAL
                     WALVWQGVITSDIWVPLRALTRSSSNARTSTRRSHRARRGRPVYAQPVSPRVSYNTPN
                     LAGRWSLLQVEPLNDTERMLALAENMLDRYGIISRQAVIAENIPGGFPSMQTLCRSME
                     DSGRIMRGRFVEGLGGAQFAERLTIDRLRDLATQATQTRHYTPVALSANDPANVWGNL
                     LPWPAHPATLVPTRRAGALVVVSGGKLLLYLAQGGKKMLVWQEKEELLAPEVFHALTT
                     ALRREPRLRFTLTEVNDLPVRQTPMFTLLREAGFSSSPQGLDWG"
     gene            complement(18208..18855)
                     /gene="rnt"
                     /locus_tag="IT892_002132"
     CDS             complement(18208..18855)
                     /gene="rnt"
                     /locus_tag="IT892_002132"
                     /EC_number="3.1.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="HAP3135348.1"
                     /translation="MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITL
                     KMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKV
                     VRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALG
                     QTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLSAAEEV"
     gene            complement(18958..19365)
                     /gene="gloA"
                     /locus_tag="IT892_002133"
     CDS             complement(18958..19365)
                     /gene="gloA"
                     /locus_tag="IT892_002133"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP3135349.1"
                     /translation="MRLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFV
                     GYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGP
                     VKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN"
     gene            complement(19446..20543)
                     /gene="nemA"
                     /locus_tag="IT892_002134"
     CDS             complement(19446..20543)
                     /gene="nemA"
                     /locus_tag="IT892_002134"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-ethylmaleimide reductase"
                     /protein_id="HAP3135350.1"
                     /translation="MSSEKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAE
                     YYRQRASAGLIISEATQISAQAKGYAGAPGIHSPEQIAAWKKITAGVHAENGHMAVQL
                     WHTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMPRALELEEIPGI
                     VNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDQYGGSVENRARLVLEV
                     VDAGIEEWGADRIGIRVSPIGTFQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDW
                     AGGEPYTDAFREKVRARFHGPIIGAGAYTVEKAETLIGKGLIDAVAFGRDWIANPDLV
                     ARLQRKAELNPQRAESFYGGGAEGYTDYPTL"
     gene            complement(20580..21179)
                     /locus_tag="IT892_002135"
     CDS             complement(20580..21179)
                     /locus_tag="IT892_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416166.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP3135351.1"
                     /translation="MNKHTEHDTREHLLATGEQLCLQRGFTGMGLSELLKTAEVPKGS
                     FYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGT
                     ISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQA
                     QVLYALWLGANLQAKISRSFEPLENALAHVKNIIATPAV"
     gene            21282..21521
                     /locus_tag="IT892_002136"
     CDS             21282..21521
                     /locus_tag="IT892_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HAP3135352.1"
                     /translation="MAEQLEFFPVQSPCRGICQSDERGFCRGCFRSRDERFNWNKMSD
                     GEKQEVLRLCRQRLMRKLRANKPASSDEPEQPSLF"
     gene            21570..22466
                     /locus_tag="IT892_002137"
     CDS             21570..22466
                     /locus_tag="IT892_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAP3135353.1"
                     /translation="MVQRITIAPQGPEFSRFVMGYWRLMDWNMSARQLVSFIEEHLDL
                     GVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSKCGIATTAREENVIGHYITD
                     RDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVADAFKHLHQSGKVRHFGVSNF
                     TPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGGRLF
                     NDDYFQPLRDELAVVAEELNAGSIEQVVYAWVLRLPSQPLPIIGSGKIERVRAAVEAE
                     TLKMTRQQWFRIRKAALGYDVP"
     gene            22547..23068
                     /gene="sodC"
                     /locus_tag="IT892_002138"
     CDS             22547..23068
                     /gene="sodC"
                     /locus_tag="IT892_002138"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC2"
                     /protein_id="HAP3135354.1"
                     /translation="MKRFSLAILALVVATGAQAASEKVEMNLVTSQGVGQSIGSVTIT
                     ETDKGLEFSPDLKALPPGEHGFHIHAKGSCQPATKDGKASAAESAGGHLDPQNTGKHE
                     GPEGAGHLGDLPALVVNNDGKATDAVIAPRLKSLDEIKDKALMVHVGGDNMSDQPKPL
                     GGGGERYACGVIK"
     gene            complement(23069..25081)
                     /locus_tag="IT892_002139"
     CDS             complement(23069..25081)
                     /locus_tag="IT892_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP3135355.1"
                     /translation="MNASSWSLRNLPWFRATLAQWRYALRNTIAMCLALTVAYYLNLD
                     EPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAIAALLLAGHTLNEPWFFLLSMSA
                     WLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGI
                     LCGGMMMMILPSSSDATALLTALKNMHARLLEHASLLWQPETTDAIRAAHEGVIGQIL
                     TMNLLRIQAFWSHYRFRQQNARLNALLHQQLRMTSVISSLRRMLLNWPSPPGATREIL
                     EQLLTALASSQTDVYTVARIIAPLRPTNVADYRHVAFWQRLRYFCRLYLQSSQELHRL
                     QSGVDDHTRLPRTSGLARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDAGANALTLA
                     AISCVLYSAVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLAT
                     MQLLKLQMPKFAALWGQLIVFMGSFIAVTNPPVYDFADFLNDNLAKIVGVALAWLAFA
                     ILRPGSDARKSRRHIRALRRDFVDQLSRHPTLSESEFESLTYHHVSQLSNSQDALARR
                     WLLRWGVVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATL
                     EELQRICDSLARHHQPAARELAAIVWRLYCSLSQLEQAPPQGTLAS"
     gene            complement(25081..25938)
                     /locus_tag="IT892_002140"
     CDS             complement(25081..25938)
                     /locus_tag="IT892_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416161.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAP3135356.1"
                     /translation="MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQ
                     VSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKAN
                     NEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSG
                     WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKT
                     LQGHVSSIGRAIYDQSVESDSSLIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSG
                     TTCSIAVGQ"
     gene            complement(25941..26177)
                     /locus_tag="IT892_002141"
     CDS             complement(25941..26177)
                     /locus_tag="IT892_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1656 domain-containing protein"
                     /protein_id="HAP3135357.1"
                     /translation="MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVVHRLL
                     RGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW"
     gene            26378..26812
                     /gene="slyA"
                     /locus_tag="IT892_002142"
     CDS             26378..26812
                     /gene="slyA"
                     /locus_tag="IT892_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416159.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SlyA"
                     /protein_id="HAP3135358.1"
                     /translation="MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLP
                     PDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISE
                     MEAVINKTRAEILHGISAEELEQLITLIAKLEHNIIELQAKG"
     gene            complement(26859..27326)
                     /gene="slyB"
                     /locus_tag="IT892_002143"
     CDS             complement(26859..27326)
                     /gene="slyB"
                     /locus_tag="IT892_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein SlyB"
                     /protein_id="HAP3135359.1"
                     /translation="MIKRVLVVSMVGLSLVGCVNNDTLSGDVYTASEAKQVQNVSYGT
                     IVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTVGGGTGRSLATAAGAVAGGVAGQGV
                     QSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSPGQRVVLASNGSQVTVSPR"
     gene            27600..28709
                     /gene="anmK"
                     /locus_tag="IT892_002144"
     CDS             27600..28709
                     /gene="anmK"
                     /locus_tag="IT892_002144"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HAP3135360.1"
                     /translation="MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSL
                     KQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVW
                     HEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPT
                     ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGK
                     VILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAV
                     TISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAF
                     AWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP"
     gene            28807..29136
                     /gene="mliC"
                     /locus_tag="IT892_002145"
     CDS             28807..29136
                     /gene="mliC"
                     /locus_tag="IT892_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416156.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-type lysozyme inhibitor"
                     /protein_id="HAP3135361.1"
                     /translation="MTMKKLLIIILPVLLSGCSAFNQLVERMQTDTLEYQCDEKPLTV
                     KLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVFWSKGDEATVYKRDRIVLNNC
                     QLQNPQR"
     gene            29195..29851
                     /gene="pdxH"
                     /locus_tag="IT892_002146"
     CDS             29195..29851
                     /gene="pdxH"
                     /locus_tag="IT892_002146"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HAP3135362.1"
                     /translation="MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACE
                     AKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLL
                     FPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKF
                     LELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
                     "
     gene            29980..31254
                     /gene="tyrS"
                     /locus_tag="IT892_002147"
     CDS             29980..31254
                     /gene="tyrS"
                     /locus_tag="IT892_002147"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAP3135363.1"
                     /translation="MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTA
                     DSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVD
                     KIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQR
                     LNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQN
                     QVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFT
                     FMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSA
                     LSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQS
                     DPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK"
     gene            31316..32176
                     /gene="pdxY"
                     /locus_tag="IT892_002148"
     CDS             31316..32176
                     /gene="pdxY"
                     /locus_tag="IT892_002148"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310372.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal kinase PdxY"
                     /protein_id="HAP3135364.1"
                     /translation="MKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHT
                     QYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKAA
                     NPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNNV
                     EEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQP
                     VGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIAK
                     PEHYFSATKL"
     gene            complement(32220..32825)
                     /gene="gstA"
                     /locus_tag="IT892_002149"
     CDS             complement(32220..32825)
                     /gene="gstA"
                     /locus_tag="IT892_002149"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HAP3135365.1"
                     /translation="MKLFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYF
                     AVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIA
                     TELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADACLFT
                     VLRWAYAVKLNLEGLEHIAAFMQRMAERPEVQDALSAEGLK"
     gene            complement(32931..34433)
                     /gene="dtpA"
                     /locus_tag="IT892_002150"
     CDS             complement(32931..34433)
                     /gene="dtpA"
                     /locus_tag="IT892_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpA"
                     /protein_id="HAP3135366.1"
                     /translation="MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIM
                     AVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGY
                     ALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVN
                     IGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINY
                     RNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMI
                     VAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHSILGLAVEPEQYQALNPFWIIIGSP
                     ILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQ
                     SIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDP
                     LMSLEVYGRVFLQIGVATAVIAVLMLLTAPKLHRMTQDDAADKAAKAAVA"
     gene            complement(35044..35679)
                     /gene="nth"
                     /locus_tag="IT892_002151"
     CDS             complement(35044..35679)
                     /gene="nth"
                     /locus_tag="IT892_002151"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAP3135367.1"
                     /translation="MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATD
                     VSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNG
                     EVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
                     EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI"
     gene            complement(35679..36374)
                     /locus_tag="IT892_002152"
     CDS             complement(35679..36374)
                     /locus_tag="IT892_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HAP3135368.1"
                     /translation="MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLA
                     TTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFI
                     PLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDG
                     ADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRAEAA
                     AERALPNGETGNV"
     gene            complement(36378..36998)
                     /gene="rsxG"
                     /locus_tag="IT892_002153"
     CDS             complement(36378..36998)
                     /gene="rsxG"
                     /locus_tag="IT892_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxG"
                     /protein_id="HAP3135369.1"
                     /translation="MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKA
                     LFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIAKQDDKPVAAVLEATAPDGYSG
                     AIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAM
                     KKDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE"
     gene            complement(37002..38060)
                     /gene="rsxD"
                     /locus_tag="IT892_002154"
     CDS             complement(37002..38060)
                     /gene="rsxD"
                     /locus_tag="IT892_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxD"
                     /protein_id="HAP3135370.1"
                     /translation="MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTL
                     VQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGT
                     VFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQ
                     VIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEQIMQYPIYSGILAGA
                     GWQWVNLAWLAGGVWLLWQKAIRWHIPLSFLVTLALCAMLGWLFSPETLAAPQIHLLS
                     GATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANIT
                     VPLIDYYTRPRVYGHRKG"
     gene            complement(38061..>38300)
                     /locus_tag="IT892_002155"
     CDS             complement(38061..>38300)
                     /locus_tag="IT892_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135371.1"
                     /translation="AKARKREQQPANAEPEEQVDPRKAAVEAAIARAKARKLEQQQAN
                     AVPEEQVDPRKAAVAAAIARAQAKKAAQQKVVNED"
BASE COUNT         9644 a         9626 c         9967 g         9063 t
ORIGIN      
        1 ttacttacct gtacgcattc tttcgaattt agtgttatca gataagtttg gttgagattt
       61 ttagaatttg agaaatttca gacagggatg aaaagggcgc taaccgccct tgattaaatt
      121 ctgtcaggcg agttttgcct gattgatttg actaagtggc tcattgacat cgaaaacttt
      181 ggcgacaact tcctcaacgc cgagattttt cagtcgggca gtatgttttt ccagataggc
      241 aagggcgctt ttttcatcag tgaaaaggta gatcccaccg gcttcgtggt tcttttcact
      301 ttctgtccat accttccaca gaaaaccagg ttcctgatta atcgactcag caagtggttt
      361 aagctgctca gccattgcgt cgccaaatgg gccattaaaa gcaaaatgaa gttgtaacaa
      421 agttgccata gcgattctcc ttctgataac gcatacgaag acagtgtaaa tcttttaacg
      481 tattggatac agagaagaaa cagagggaaa aaggagaaga ccagattaag aaaatctggt
      541 gcgtccgagt ggactcgaac caccgacccc caccatgtca aggtggtgct ctaaccaact
      601 gagctacgga cgcaggatgg tgcgttcaat tggactcgaa ccaacgaccc ccaccatgtc
      661 aaggtggtgc tctaaccaac tgagctatga acgcaacgtt gtaggtgaca acggggacga
      721 atattagcgg cagagtggga aggtggcaag aggcaaaacg taattttctg cgctatttcg
      781 accgtttgca gagcttttaa gcaaattggc tatattttgt tgatttgcaa gggtgatttt
      841 tattcaggat cgcatttaca tctgatacaa cccaataatt cgtgtatcag agtttaaaca
      901 gagttgtttg ccaccatctc aaatctgtcg tggataaatc ctccgtagcc tttacactta
      961 ggtagcaata aaggcacaca gatgcagcaa aggaataaat catgggatct gatgcgaaaa
     1021 acttgatgag cgacgggaac gtgcaaattg ttaagaccgg cgaggtcatt ggcgcgacgc
     1081 aacttactga aggcgagttg attgttgaag ctggcggaag agccgaaaat accgtggtca
     1141 cgggggctgg ctggttgaaa gtggcaaccg gtgggatcgc caaatgcaca cagtacggta
     1201 acaatggcac gctatcggtc agcgatggtg ccattgccac agatattgtt cagtccgagg
     1261 gtggcgcaat tagtctctct acgctcgcta cggttaatgg ccgccatccc gaaggtgaat
     1321 tcagcgttga taaaggttat gcctgcggtt tgttgctgga aaatggcggt aacctgcgtg
     1381 tactggaagg acatcgcgcg gaaaaaatca ttctcgatca agagggcggc ctgttggtta
     1441 atgggacaac ctcagcggtc gtggtagatg aaggtggtga attgttggtg tatccaggtg
     1501 gggaagccag caattgtgag attaatcagg gcggcgtttt tatgctggcc gggaaagcca
     1561 gtgatacgtt gcttgctggt ggcaccatga ataatctcgg tggtgaagac tctgacacta
     1621 ttgttgagaa tggatccatt tatcgtctgg ggacggatgg ccttcagctc tacagttccg
     1681 gtaagacgca aaacctgtcc gtgaatgtgg gtggtcgggc tgaagtgcat gccggtacgc
     1741 tggaaaacgc ggtaatacaa ggtgggacag tgatcctgtt gtcacccacc agcgcggacg
     1801 aaaattttgt cgtagaggaa gatcgcgcac cggttgaact gaccgggagt gttgcattac
     1861 tggacggcgc ttcaatgatt attggttatg gcgcagagct gcaacaatca acgattactg
     1921 tacagcaggg cggtgtgttg attctagacg gcagtacggt aaaaggtgac agtgtcactt
     1981 tcattgttgg taacatcaat ctgaatggtg gaaaactgtg gctgatcact gatgcggcaa
     2041 cgcatgtgca actgaaagtg aaacgcctgc gcggagaggg agcgatttgc ctgcaaacca
     2101 gtgcaaaaga aatttcacct gacttcatca atgtgaaagg ggaagttacc ggggatatac
     2161 acgttgagat aacagatgcc agtcggcaaa ctctgtgtaa cgctctgaaa ttacagccag
     2221 acgaagacgg gattggcgca acgctccagc ctgcgtaaaa atacaggcgc aacccgtgaa
     2281 ggttgcgcct tgtctttatt agcgggatgc tcgttgcaga atgatggctg acggcagacg
     2341 ttgcaggaac cgcatacgca acatcatcat aatggctgcc gacgtcaggc caataataaa
     2401 gcctatccag aagcctgctg gccccatagg ttcaacgacc agatcggtca gtgccagaat
     2461 atagccgctt ggcaagccca gcacccagta agccgtaaag gtaatataga aaatggaacg
     2521 cgtatcttta taaccacgca aaatcccact gccaatcacc tggattgagt cagaaatctg
     2581 atataccgcc gccagcaaca tcaaatgcgc agccagcgtt acaacctcgg gattgtcgtt
     2641 gtacaacagg gcgatttgct cccgcagtga aaccgtgaaa atggccgtca gggttgccat
     2701 acagacaccc accataagcc cggtccgcgc agcggtttgc gcatccagcg ttgagccctg
     2761 acccagacga taacctacgc ggatagttac cgctgccgcc agcgacattg gaagcacgaa
     2821 cattagtgaa ctaaagttca gggcaatctg gtgtcctgcg acatcaacaa taccgagcgg
     2881 agacactaac agagccacga cggcaaacag tgtcacttca aagaacagtg ccagcgcaat
     2941 cggcaaaccg agttgaatca gtcgtttcat aaccgcagga tcgggttttg cggtgccttt
     3001 ttcgttacga atatcgcgca tggagcgggc gcgtttaatg taagaaacca tggcaaggaa
     3061 catgacccaa tacaccgccg cagtagccac gccacaacca acgccaccga gctcaggcat
     3121 accgaaatga ccataaataa agatatagtt caccgggatg ttcaccagca ggccgataaa
     3181 gcccattacc atacccggct tggtttttgc cagaccttca cactggttac gggcaacctg
     3241 gaagaacaga tatcccggcg cgccccacaa caacgcacgc agataaccca cggctttgtc
     3301 cgccagagcc ggatcgatgt tttccatgga gcggataatg taacctgcat tccacagcac
     3361 cagcataatg agaacggaaa caaaacctgc cagccagaaa ccttgtcgca cctgatgcgc
     3421 aatgcgctca cgtcgaccgg aaccatttaa ttgcgcgata accggcgtta atgccagcag
     3481 cagtccgtga ccaaagagga tcgccggaag ccagatagaa gtaccgatag cgaccgccgc
     3541 catgtcggtg gcactatagc cgcccgccat cacggtatcg acaaaaccca tcgcagtttg
     3601 ggcgatttgc gcgagaatca ccgggattgc taatgctaat aacagacgcg cttcactgat
     3661 atacttctgc acgtgaacac cttttatttg tagttatatg agagactaaa aagccgcctg
     3721 aatgggcagc aaaaagaaga agcaggggaa attcagtcta ttgtagcgag gatttattaa
     3781 ttctccagtg aaaaaatagc cattcttacc ccttcactgg taagggcgtt ttccacctgc
     3841 tattgtgctg aacagaatgt cttaactgat ttcaggagtt gtaagtatgt ttacggggat
     3901 tgtacagggc accgcaaaac tggtgtcgat tgacgagaaa ccaaattttc gtacgcatgt
     3961 ggtggagtta cccgaccaca tgctggacgg cctggaaacc ggtgcttccg tggcgcataa
     4021 cggttgctgc ctgaccgtga cggaaattaa cggcaaccat gtcagttttg acctgatgaa
     4081 agaaacgtta cgcattacca atcttggcga tttaaaagtg ggggattggg taaacgttga
     4141 gcgtgcggcg aaattcagtg atgaaattgg cggacactta atgtcaggtc atattatgac
     4201 cactgctgaa gtggcgaaaa tattaacctc agaaaataat cgccagatct ggtttaaagt
     4261 ccaggatagt cagttgatga aatatattct gtacaaagga tttattggca tcgacggtat
     4321 tagcctgacc gtcggcgaag tcacgccaac gcgtttttgc gtccatttaa ttccggaaac
     4381 actggaacgc acgactcttg ggaagaaaaa acttggcgca cgcgtcaaca ttgaaatcga
     4441 tccacaaact caggcagtgg tagatacggt agaacgtgtg ctggcggcac gagaaaatgc
     4501 catgaatcaa ccaggcacag aagcctgatc tgaaatcgcc cccggagagg gggcgataga
     4561 atagccttta gcgagccact cgaaggccgt tttcaacacc gcgtgagaac acgacctgcc
     4621 agagctgaat atcacgggcg cggaaagcac ctgcacaggc attcagataa taggtaaaca
     4681 ttcgtttaaa gcgttcacta tagttatccg caatttctgg ccatgcggcg aggaatcgtt
     4741 cataccacgc catcaacgta gtatcgtaat cagcaccgaa gttatgccag tcttccatca
     4801 caaagtgggg ttcgctggac tgagcaatct ggcgtacaga gggcaggcaa ccgttcggaa
     4861 aaatatattt attaatccag ggatcaacat tcagatcggt ttttttcgaa ccgatagtat
     4921 ggagcaggaa tatgccttcc ggtttcaaat tacgatccac caccgcaaaa taggtatcgt
     4981 aatttttcgg tccgacgtgc tcgaacatcc ccacagaaac aatacgatca aactggtcgt
     5041 tcaggtcacg ataatcttgc agcaaaatgg tgacatccag gccttcacag cgttcctgag
     5101 ccattttttg ctgttcggca gaaatggtga cgcccaccac gcttacgtca taattagatg
     5161 ccatgtagtg tgccagtccg ccccagccgc agccaatatc cagtacgcgc atccctggtt
     5221 ttaactgcaa tttttcacaa atcattttga gcttcgcctg ctgggcagat tccagattat
     5281 cggcatcttt ccagtaagcg caggaatatt gcatgaaggg atcaagcatg cggctgaaca
     5341 agtcattacc caaatcgtaa tgctctttgc cgactatcca ggcacgtttt ttactctgca
     5401 gattgaagag acgagcgccg gcaatacgca gcgtgtcttt gaaatgatgg gggagttggt
     5461 tctcgagacc tgcgcgtaag actttgctaa aaaacatatc cagtcggtca cattcccacc
     5521 agccatccat ataactttcg cctaacccca aagagccttc ttgcagaacg cgtttaaaaa
     5581 aatcggggtt tttcacacga atatccgccg gggcagaacc gttaatggct ataccggcac
     5641 ggctaagtaa ttcgttggcg atacggtacc agttgtcatc cggtacactg acttcttcta
     5701 tacacgatga actcatagtt tctccatcac tggtcggtga tcagaacctt aaaacagcgt
     5761 agacgctttt tgggctttgt gagaaatctc gcagaaaaaa ccgcgagtct ataatccgac
     5821 gtagaacaga gggaaaggag gaacccttgc cgaaatgact atccatagtg agtcgggaac
     5881 gatcctgtcc ccgtaaaaac ataatattta tcgtagcttt aacaactcga aattagtata
     5941 ggccgctaat ttcaatcata caacaaaatt ttgttagcag cctaagtata agtatatcga
     6001 tatagatcag tgtgattcgc tatgagcgac ttcggcattg ccatgattct ggcagccaac
     6061 ttcttcacaa cgttgcatca tgtaacccag cgcgaccagc actactgttg ataacatcac
     6121 gctggtggtg gtgagcaatg gcgtgctgat actgatcagc caggaaacta ccagacttgc
     6181 gaggaagcac agacccagtt gaagagtgtt ctgcaacgct gcggcgcgac cagttgcgtg
     6241 tgggaaggga cgcagcgcct gggcgacaac aatagggtag atcgcgccat tggcaatcgc
     6301 catcacacag aatgggatca ggatttcgac cagcgacaca tggctaatga agcccgcagc
     6361 ccaggtcgca atgacgctga cagcaaacag caccagcaac cacggtaata actgcttgcc
     6421 ttgccatttc tgcagcgcgg cgcgacagcc ataaccacca atcagaaacg cgatagtttg
     6481 cgggacataa cttaaaccaa taactgccgg gctgtagccc atttcactaa ggatgaacgg
     6541 tgaaccggtc agccatgcaa aaaaactggc tgaacaggct gcgtatatca gcacgttgcc
     6601 gcgataggtt ttagaacgta gcaggtcggt aaaggtcaga ccatcctgac tattgttacg
     6661 ggccttcgtc gtgggtttga gccagaaaat aggcagaatc agcaccacgg taatggcaaa
     6721 cagggtggcg aaaatcgcct gccaggaaaa atggaccagc agccagcttc ctaacagagg
     6781 agccagtgcc ggagatagac ccaccagcgg catgatggtc gcaaaaatac ggttaacttt
     6841 ctgtgaagga taataatctg tcactaatgc ttgccagata accgccgcgg cgcagacacc
     6901 cacagcctgt acaaaacgca ataccagcag cgtagcggcg ttttctaccc acagcatccc
     6961 cagactacct aacgcaaaaa ttgtcaggcc gattaataat accagtttac gaccataacg
     7021 gtcggagagc ggcccccaca gaagctgggc tgcggcaaaa ccggcaagga acagactaag
     7081 gctggcactg acagcagacg caggcgtttg caggtcggcc tgtatggcgg cgaaagcagg
     7141 cagatacata tcggttgcca gaaaaccgag tacgctcaaa cccgccagcc agactaaaaa
     7201 tcttttccca ggttgcatgt atattctcta aatctctcaa ttaaacaccg ccgcaaagtg
     7261 tagggagtga aattagtgtt gtgaaacggt aatatttgat gactggtttc aaaaattttg
     7321 caggcagact atgtggtcag aatattcact cgaagttgtt gatgcggtag cgcgtaatgg
     7381 tagttttagc gctgcggcac aggagctgca tcgcgttcct tctgcggtca gctataccgt
     7441 gcgtcagctg gaagagtggc tggcggtgcc gctctttgaa cgacggcacc gtgatgtgga
     7501 gctgaccgct gctggagcgt ggtttctcaa agaagggcgc tctgttgtca aaaaaatgca
     7561 gatcacccgc cagcaatgtc agcagatagc gaacggctgg cgcggtcagt tagctatcgc
     7621 agtggataat attgtcaggc cagaacgtac acggcagatg atcgttgatt tttatcgcca
     7681 ttttgatgat gtcgaacttc ttgtctttca ggaagtgttc aacggtgtct gggatgcgct
     7741 ttccgacggg cgcgtggaac tggcgattgg cgcaacacgc gcgattccgg taggcggtcg
     7801 ttatgccttc cgggatatgg ggatgctaag ctggagttgt gttgttgcca gtcaccaccc
     7861 gctggcgttg atggatggcc cgttcagcga tgatacgttg cgcaactggc cgtcgttggt
     7921 gcgcgaagac acctcgcgaa cgctacctaa acgtattacc tggttgctgg ataaccaaaa
     7981 aagagttgtc gtgcctgact gggaatcatc ggcaacctgt atctcggcag gattatgcat
     8041 agggatggtg ccaacacatt tcgccaaacc gtggcttaat gaggggaagt gggtagcatt
     8101 agaactggaa aacccctttc cggattcggc atgttgtctg acatggcagc aaaatgatat
     8161 gtcgcctgcg ttaacctggt tgcttgagta tctcggcgat agtgagacgc tgaataagga
     8221 gtggctgcgg gagccggaag agactcccgc aacgggtgat taacgacgat agtcgcggaa
     8281 cgggccgtca gccacggagc ggcgttcaat caagcgcgga tgcacttcaa tagactgcgg
     8341 ttcttcacgt ttgttgacga tacgatccaa cagcatgttg aacgctgttt cacccagcga
     8401 atcttttggc tgatggatcg tggtcagcgc cggcgtaaaa tagcgcgcgt tgcgcacgtt
     8461 atcataaccg atcagcgaaa catcctgcgg gacgcgcagg cccatttcat cagcagcaca
     8521 aagtgcgccc attgccatga tatcgccacc acagaagacg gcagtagggc gatgcggctg
     8581 cgacaggatt tgctgcatgg cgcgataacc ggattcaggt tcaaagtcac cctgcacaat
     8641 ccagctttcc ggcaccttga tcatcgcttc ttccatcgcc ttcataaaac cggcaaggcg
     8701 gcctgcgccg gtgttacgtt ccagcgggcc ggggatgacg ccgatttcgc ggtgaccgcg
     8761 ttcaatcaga taacgcccgg ccatgtagcc gccttcgaac gcgttatcaa tgaccgcatc
     8821 ggtgaagtca gcttttgctt caccccagtc catgaccacc attgggatat ggcgatactc
     8881 ttccagcatc gccagcaacg gctctgggta ctcagaacac atcaccagca gaccatcgac
     8941 gcgtttttgc gccatcatcg acagataagc ccgctgtttc tcaagattgt tccacgcatt
     9001 gcccagaatc agggtgtaac ctttctggaa gcaatttttt tcaactgctt caatgatctc
     9061 ggcaaaatag gccgcttcgc tgctggtcgc cagcaaaccg atagacttgg tgtggttaac
     9121 cttcaggcta cgcgccaccg cgctagggga gtagtgtaat tctttaatcg ctgcccacac
     9181 ggcgttgcgc gtttcttcag cgacgaaacg tgttttgttg atcacgtgtg acacagttgt
     9241 agtggaaacg tttgctcgtt tcgctacatc ttttattgtt gccattccat ttcactccag
     9301 accctaactt cagctcctgc aaaatcgcaa ggtaaacgtt tgcctttaca caccttacgc
     9361 acaacaaaag tgttgcggta cgccggaaaa acgacacgga gcgtcaggaa ggggtcaatg
     9421 gccagtacgc aaatagtgta agcgtggaat tttggccgat cttgacgaaa aggggaagtg
     9481 gtaaaaacac ttatcattat aaatgacggg agattttttc atcacagtgt gtaaaaatgc
     9541 gtaatatcac tttttgtgtg gtaataaaaa aggagaaaac ttgatgagca ccgaccttaa
     9601 attttcactg gtaacaacga ttatcgtcct cggtttgatc gtagccgtgg gtttgactgc
     9661 cgcgctgcac tgatttcctc tcgagggagc gcgttctccc tcgcatctcc ttcctgtttg
     9721 ttagcaaaat ggcaaaagtg ttttctcttt ttgttatttt catttttttg tgattgctgt
     9781 catgctttcg ccactttaat gaatatcgcg taatgacgcg aagaggtgga gataaggcat
     9841 gaaaattaac tatccgttgc tggcgctggc gattggcgcg tttggtatcg ggacaacgga
     9901 gttctcgcca atgggcttgt tgcccgtcat tgcgcgcggt gtggatgtct cgattcccgc
     9961 tgccggaatg ttaatcagtg cctatgcagt tggcgtaatg gttggcgcgc cgctgatgac
    10021 gcttctactt tctcatcgtg cccgccgcag tgcgttgatt ttcctgatgg caattttcac
    10081 gctcggcaac gtactttccg ccatcgcgcc ggattatatg accctgatgc tttcacgcat
    10141 tttgaccagc ctgaatcacg gagcattttt tggtttgggt tcagtcgtgg ccgcaagcgt
    10201 ggtgccaaaa cataaacagg ccagcgcagt tgccactatg tttatggggt taaccctggc
    10261 aaatatcggt ggcgtgccgg cggcgacctg gttgggtgaa accatcggct ggcggatgtc
    10321 atttctggca acggcggggc tgggagtgat ttcaatggta agtctgttct tctcattacc
    10381 taaaggtggt gcaggggcac gacctgaagt gaaaaaagag ctggcggtat taatgcgtcc
    10441 gcaggtgctg tctgcattgc tgacgacggt actgggagct ggtgcaatgt ttactctcta
    10501 cacctatatc tctccggtac tgcaaagtat tacccacgca acaccggtgt tcgtcacggc
    10561 aatgctggtg ctgattggtg tcggattctc tatcggtaac tatctcggcg gcaaactggc
    10621 agatcgttca gttaacggca cgttgaaagg ctttttgttg ttgttgatgg tgattatgct
    10681 ggcaatcccg ttcctggccc gcaatgagtt cggcgcagct attagcatgg tggtgtgggg
    10741 cgcagcaacc tttgcggtcg taccgccgtt acagatgcgc gtgatgcgtg tcgccagtga
    10801 agcgccaggt ctgtcttcat cagtcaatat tggtgccttt aatcttggaa atgcgctggg
    10861 agcagctgct ggtggtgcgg taatttccgc tgggctggga tacagctttg tgccggtgat
    10921 gggagcgatt gtcgcgggac tggcattatt gctggtgttt atgtcagcca gaaaacaacc
    10981 tgaaacagtt tgcgttgcta acagctaatt aaacaaaaac gcagaaggat aaccttctgc
    11041 gttacagttg ctgacaacgt gcgatttatc ttgccggatg cggtgttaac gactcatccg
    11101 cgttgacatg aaaagacgcg ttaggcgtcg tatcatgcag cgcttgtcgg atgcggcgag
    11161 tgccttatcc gacctacatc gatgatccgc gtaggcctga taagcgtagc gcttcaggca
    11221 atgctgcatt tgccatcagt tattatgcag cgagattttt cgctacgaat tcccagttca
    11281 ccagcgccca gaagtgctcc agatagccag gacgtgcatt gcgatagtcg atgtaataag
    11341 cgtgttccca gacatcaacg gtcagcagcg gagtcgcatc ggtggtcagc ggagtacccg
    11401 cgttagaggt tgaaacgata gccagtttgc catcgctgtt tttcaccagc caggtccagc
    11461 cagaaccaaa gtttttgatc gctgcatcag taaactgcgc tttgaaatcg gcaaagctgc
    11521 caaaagatgc ggcgatagct tcagcgactt ttccagtcgg ttcgccaccg gcgttcggtg
    11581 ccaggcagtt ccagtagaaa gtatggttcc agacctgagc tgcgttgttg aatacgccac
    11641 cttcagagct gcgaataatc tcttccagtg atttaccttc aaacgcggta cctttaatca
    11701 ggttgttcag gttagtgaca taagtctgat ggtgcttgcc gtagtgatac tcgatggttt
    11761 ccgcagaaat gtgcggtgcc agagcatctt tagcatatgg tagtgcaggt aattcgaatg
    11821 acattgctac tctcctttat tattaatttg catacgtaca atagccttat tgtgcgtatg
    11881 gatagggtag caaattaaaa ggtgagacaa aagatgaact taccctgttg ccgtaacaac
    11941 agggtaaagt tttagcgaag tgtttttggg gtcattaccc gacgagcgcc aacatagtgg
    12001 cgctgccagt agtcttcact gagagaagtg atttgaattt cctgacctgt gcgcggtgac
    12061 tgaataaatt tgccgttgcc gacatacacg ccgacatgat cggctgtgcc gcgtccctga
    12121 gtacggaaaa agaccaggtc gccgtttttc agttcactac gttcgattgg cgctgcatca
    12181 cgcaggtgat acatttcatt cgccgtacgc ggaatacgaa ttttcaccaa atctttataa
    12241 gcgtaataaa ccaggccgct gcaatcaaaa ccggtactcg gtgagctgcc accccaacga
    12301 tatggcttac caatttgctg catcagttta ttcattgcca ctttcgtagc tttttgcacc
    12361 ttcgctttgt gcgcgtcggc aagagttcct gacgcggcat ttttgacttt cacacaatgc
    12421 gatttatagc ccttacgttt ggtacacttt tcggtaaagc tggctgaggc cgttttattg
    12481 acggcgtgtt tgctgcgagt tttggcgttt ttagaagcgg taatggaaga ttttttaacg
    12541 gaagaagcgg ttttgctttt ggtcgtactt ttactggcgg cttttttcgc tgttttctgg
    12601 gtctttttgg tggttgccgt gcttttcttt ttatctgctt ttttggtgat atgagtggta
    12661 gcagaactct ccctggcttg ctttgaagca tgggccatag gcgttaaagg cagggtggta
    12721 aaaagtaaag cacagagcgt gatcgaaata cggtttatcc gcgccactga gcgtccctct
    12781 gttaaggcag gtctatcatg cctgcgtctg atttacaaaa cttgatgatt ctaatgcata
    12841 gaagaagaga aagttaatag cttttattgt taaaaaatac gtttcgttgg cgagcgcaaa
    12901 aaaatgcagc agtgaaagct aaaaatggtt ataaatacgc cagtttgccg gcatcagaga
    12961 agaaacgaat atttgaaatg caacaaatag agcaaaggga taaaatagca aaagcgtgat
    13021 gaaaatgtta ttttccgatg ccgcactgac ccgctacaat gtcagattac tgccgtaaag
    13081 aagtttgagg aagcaagaca atgagcacca ctatcgaaaa aatccaacgc cagattgctg
    13141 aaaacccgat cctgctgtac atgaaaggtt caccgaaact gccgagctgc ggtttctctg
    13201 cccaggcagt ccaggcgctt gccgcatgtg gcgaacgttt tgcctatgtt gatattctgc
    13261 agaatccgga cattcgtgcg gaactgccga aatatgctaa ctggccgacc ttcccgcaac
    13321 tgtgggttga cggcgagctg gtcggcggtt gtgatatcat gatcgaaatg tatcagcgtg
    13381 gcgaactgca gcagctgatc aaagaaactg ccgctaaata caagtctgaa gagccggacg
    13441 cggaataatc cgtcctgcaa tactgacgga tgcgaacggg catccgtcag tcctttctct
    13501 atccccaatc cagcccttgt ggcgaacttg aaaatcccgc ctcacgcagc agcgtaaaca
    13561 tcggcgtttg ccggacaggt agatcattca cttctgttag cgtaaagcgc agccgtggtt
    13621 cgcgacgcag tgcggtagtc agcgcgtgga aaacctctgg ggcgagtaat tcctcttttt
    13681 cctgccagac cagcattttt ttgccacctt gcgccagata gagtaacaat ttgccgccag
    13741 aaacgaccac cagcgcaccc gcccgacgcg ttggaaccag cgttgccgga tgtgcaggcc
    13801 agggcagaag atttccccac acattagccg gatcgttggc agagagcgcc actggtgtat
    13861 agtggcgcgt ttgcgtggct tgtgtcgcca gatcgcgcaa tcggtcaata gtcagacgtt
    13921 cagcgaattg cgcgccaccc agaccttcta caaaacgacc tcgcataatt cgcccggagt
    13981 cttccatact tcgacaaagc gtttgcatcg atggaaaccc gccagggata ttttcggcta
    14041 tcaccgcctg acgactgatg atgccgtagc ggtcgagcat attttccgcc agcgccagca
    14101 tcctttcggt atcgtttagt ggctccacct gcaataacga ccagcgtcca gccagatttg
    14161 gtgtgttgta agatacccgc ggcgagacgg gttgcgcata gacaggacgt ccacgacgag
    14221 cccggtgact gcggcgagtt gaggtgcgtg cgttggaact gctgcgggtg agggcgcgta
    14281 acggtaccca aatgtcgctg gtgatgacgc cttgccagac cagcgcccat aacgcctctt
    14341 gcagggcaga gagatcaacc gattcgccga ttttgtcgcg tatccgttgg ctgatttgtt
    14401 gtgcaaacca ggctcctccg tcagccagaa cagcgactat cgcttgttgc agcgccgaac
    14461 gattcgcctg atccgcttcg gcgggagtga acgattctgc agcatattcc tgtagatgca
    14521 gtgccaccag gccgtcatct tcacccagtt ttttttgccc cgaccagata accgcaccgg
    14581 ttgccagtaa ttcatcgagc atttctgacg aatagtcgcg tacgcgggca ggcaggatct
    14641 ggctttccca gagtgaggcg ggtaaaccga ctccggcaag ctgttcgatc acccgcatca
    14701 cgccatctac gccctcataa acgcctggcg atgttgaggc aaagagcgcc gggctaccat
    14761 cggtggcggg taatacgccc tgacgttcca gcagcaatcg cgcataggtc gtggctgcaa
    14821 cgggacgcgt cgcttctctg gcggcttgca gcgagcgcaa acgcagacga cgaaatactt
    14881 catcgctcac ccagatgtct tgttgcagat tcatcaccag accctgttca cgcagttgct
    14941 gaagctgctc ttcgacaatg gcaataccga gactaaactc atgagccagt tgttcagccg
    15001 tgaccagagc atgagcccgg agatagcgca gaaagaggtc gcgaagcggg taactgactc
    15061 tatgtaaata aatctctggc aatgactctg gtagtcgtac gccgagggca tcacgcagcc
    15121 tggcggcatc atccatacag gcaagacgct cctgtccgct aatcatcgct gggaagattc
    15181 gttttactgc aagaagattt tccagatacg acgcaacctc ttcactgctg cctgtatgcc
    15241 gttgcgccag gtcttcaacg gtcattggcc ccagttcgcg cagcaggtcg aacaatcctt
    15301 cttcaccttt cgctcttctg ccaggagcca gtcgttgcaa ctcttcttcc acctggcgaa
    15361 tgacctgcgg gtcgagtaat tcccccggat cgacctgtcc gagtagattg cgcagtaact
    15421 cgctgtccag cgacagtacg gatgcccggc gctctgccag cggggcgtcg ctctggtaca
    15481 taaattccgc gacatagccg aacaataaac ttgtggcgaa aggcgagggc gtagtggtcg
    15541 ttacatcgga tatttgaatt tcgccaccgt tcaggcgacg catcaaacgt tccagtgcgg
    15601 gaagatcata aacatcttgc agacattcgc gtagggtttc gagaatgacc ggaaaatccg
    15661 gatatccctg agcgatttcc agcaactgac tggcgcgcag ccgttgttgc caaagcgggg
    15721 tgcgatggcc cggagtgcgc cccggcatta ataatgcccg cgcggcgcat tcgcgaaaac
    15781 gggcggcgaa aagtgccgag ctgcctaccg cctcgcggac aatttgcagc aacttttctg
    15841 gttcaaacaa aaaaatcgcg gcatcgggca atttaccatc ggtgtcagga atacgtgcaa
    15901 caatgccgtc atcactggcg accaccgacg cgtcagcgcc ccatagcgca tgtattcgcc
    15961 cggcaatcgc caccgcccag ggttcatgca cccgtcttcc atagggagag tgcaaaataa
    16021 tacgccagtc accaatttca tcacggcacc gttcgaggac cagatggcga ctccccggaa
    16081 cgatgcccgt cgcgttgcgc tgctcctcaa tcaacccctg aatattggcg atcgtatttt
    16141 cttctgccag ccacggggga atagtcccgg aaaagaacgc gccatccgcc agcaaatgaa
    16201 gaaaatcgcc gatcatctcg cctaattcag ccggacgtcc gttaccttca ccacgccaga
    16261 aggggagccg ggcagaacga cccggagcag gagtcacaat cacctgatcg cgggtgattt
    16321 gctggatccg ccatgaggta gcgccgagag tgataatgtc gttcacccgc gactcatata
    16381 ccatctcctc atccagttca cccacccgcc gcgaaccggc cttttcttca ccttcgggta
    16441 ataacacgct atacatgcca cgatccggaa tggtgccgcc gctggtaacc gccaacaatt
    16501 gagcgccagg tcgggcggtc aatatcccgg tctccctgtt ccagaccagt ttggggcgaa
    16561 aagcagaaaa atcgccagag ggatagcgcc cggaaagcat atccagcgtg gcgtcaaaaa
    16621 cacgtcttgg cagatctttc cacggtgcgg cacggcgtac gcgggagtac cattcgtcta
    16681 cctgtaatgc atccatcgcc gcggcggcaa cggtttgctg cgcaaggacg tcgagaggat
    16741 tatgcggtgg tgtcaggttt tccagcctgc ctgcgaacat acactctaca atgactgcgg
    16801 aatcgactaa atcacgccgg gtacggggga aaaacagccc tttagataca ccgccaacct
    16861 gatgtccggc gcgaccaatg cgttgtaacc cactggcaac agaaagcggc gttgccacct
    16921 gaatcaccag atccaccgcg cccatatcaa tccccagttc aagactggag gttgcgacca
    16981 cgcagcgtaa ttcacccgat ttcagcgcct gttcggtgat tgctcgttgt tctttagaga
    17041 cggagccgtg gtgtgagcgg gcaataaaaa cgtcgctact ttgtacacgg ttagaggttg
    17101 cgccggaggt cgactcgaaa tgggccgcat caacggcgat agacggggaa cgctgtaagc
    17161 gtgcggcgta aagctcattt aatcgtgccg tcagtttttc cgccagcccc cgcgaattag
    17221 taaagacaat ggtcgagcga tggcgcaaca cttcatcaag gatacccgtt tcaatatatg
    17281 gccagatgga gccttcccgg ccggcatggc tgtcttcgcc ggtgccgctg gcgaccgatg
    17341 agacatcatc catattggcg accggtacga caattcgtat ctgcggatgg cgcattgcgg
    17401 gcgggttgac taccgtaacc gggcgatcgc caccaagaaa tgctgccaca tcgctggctg
    17461 agcgcacagt ggcagaaagg ccaattcgct gtgctgaggt gtggagcagc gcatcgagcc
    17521 gctccagact taacgccaga tgcgcaccac gtttactgcc cgctaccgcg tggacttcat
    17581 caataattac cgtttcgacg ccgcgtagcg tttcgcgcgc gcgggaggtc agcatcagat
    17641 agagtgattc gggtgtggtg atcagaatat ccggcggatt acgggtgagt ttgctgcgtt
    17701 cctgtgcagg cgtatcgcca gtacggatcc ctacgcgaag attgacttcc gtttcgccgc
    17761 gccgccgccg ttcatcggca atacccttca acgggatctg caagttgcgc tgaacgtcgg
    17821 tgcccagggc ttttatcggt gaaatataga ggatgcgtga ggttttacgc ttatgcgcct
    17881 cgcgggtatc ttcgccgcct tcgcggaaga gccgatcgag ggcgtagaga aatgctgcca
    17941 gcgttttccc ggagccggtc ggtgcaatca ccagcgcatg ttcgcttcgc gccgccacat
    18001 gccaggtttg cggctggaca gcggtcggct gtttaaaggc gcgaagaaac cagtcgcggg
    18061 tcgccggtga aaacacgtcc ggcaggagcg atgaagggtc tggattatct gccattaacg
    18121 ctattccccg tgaatatcat gcaggatgcg tggaatagcc tcactataga tgcctgaatc
    18181 attgcatgtc atcaggcatc gactcgatta cacctcttcg gcggcagata gcggccagcc
    18241 tcccagacgt ttccagcggt tgacgatttc acaaaacagc acagcagtgc gttcggtgtc
    18301 gtacagcgcg gagtgcgcct gggtgctgtc gaagtccatg ccagcggtct ggcaagcctt
    18361 tgacaatacg gtttgtccga gtgccagccc ggccagtgca gcagtgtcaa aagtggcgaa
    18421 agggtggaac gggttacgtt tcagtgaggc gcgttctgcg gcggccatca taaagctgtg
    18481 atcaaaattg gcattgtgcg ccaccataat ggcgcggtta cagccgctcg ctttaatacc
    18541 tttacgtaca actttaaaaa tttcgtgcag cgcctcgtat tcgctgaccg cgccgcgatc
    18601 gggatcgttc gggtcaatgc cgttgaaggc gagggcttct ggttgcaaat ttgcgccgac
    18661 aaatggttcg acgtggaaat gtaatgtggt gtccggcatc agccagcctt gttcatccat
    18721 tttcagggtg atggcggcaa tctcaagcag cgcatcggtt ttggcgttaa atccggctgt
    18781 ttcaacatcg atcacaacag gataaaaacc acgaaaacgg tcgcacagac cggtaagttg
    18841 agcgttatcg gacatctgat tctcttaata cggataaatt gcagcgcgca ttatgacaaa
    18901 tattacttgt cgatgcagta aagatgcggg cgcgatgagt tcacgcccgg caggagatta
    18961 gttgcccaga ccgcgaccgg cgtctttctc ttcgattaac tcaattttgt aaccgtccgg
    19021 atcttccaca aacgcgataa ccgtagtacc gccttttacc ggacccgctt cacgggtcac
    19081 gttacccccg ttttgacgga ttttttcgca cgcttcagcg gcgttatcta cgctaagcgc
    19141 gatgtgacca taagcagtgc cgagttcgta tttatccacg ccccagttgt aggtcagttc
    19201 aatcaccgct tcttcggttt ccgggccgta gccaacaaac gccagtgagt atttgtattc
    19261 cgggttttcg ctggtacgca gcagtttcat gcccagcact ttggtataaa aatcgatgga
    19321 gcgttgcaaa tcgccaacgc gcagcatggt atgaagaaga cgcatctttt tatcctcaaa
    19381 atggctaaca gattcaaaat gttgttttag tatagcggcg gctttacgcc gctcgcaatg
    19441 ttggattaca acgtcgggta atcggtatag ccttccgcgc cgccaccgta gaaactttcg
    19501 gcacgctgtg ggttaagctc agctttgcgc tgcaagcggg cgaccagatc cgggttcgca
    19561 atccagtcac gaccaaatgc caccgcatca attaaccctt tgccgatcag cgtttcagct
    19621 ttttctactg tgtatgcacc tgcgccgata atcggaccgt ggaaacgggc gcgtactttt
    19681 tcgcggaacg catcagtata cggttcaccc cccgcccaat ctggttctga catatgcaga
    19741 taagcaatgc cgcgtttacc cagttgttca atcagataca gtgcatcggc ttcttcattc
    19801 gggccgttat ctgtgttctg gaaagtaccg attggtgaaa cgcgaatgcc aatgcgatcg
    19861 gcaccccatt cttcaatccc ggcatcgacc acttccagta ccaaacgtgc gcgattttcc
    19921 acgctgccgc cgtactgatc ggtacgatgg tttgaagaag gagaaaggaa ctgatgcagc
    19981 aaataaccgt gagcagagtg gagctctacc agatcaaaac cggcttcacg cgcgttagca
    20041 atggcctgac ggaaatcatt gacgatacct ggaatctctt ccagttcaag cgcacgcggc
    20101 atggatgttt caacacggat cgcctgacca ttttcatcgc gcagagaagt acgtgttccc
    20161 gcgctaagtg ctgaaggcgc taccggtgcc tgaccgccag gttgcaggct ggcgtgagaa
    20221 atgcgtccgg tgtgccacag ctgcacggcc atatgaccat tttcagcatg aacgccagcg
    20281 gtgatttttt tccatgcggc aatttgctcc ggactatgga tgccaggcgc acctgcatat
    20341 ccttttgcct gggcagaaat ttgcgtggct tcactaataa tcaaaccggc actggcacgt
    20401 tggcgatagt attccgccat caacggggta ggaatgtcac ccggttcaat actgcgcaga
    20461 cgcgtcagcg gtgccataaa aatacggttt gccgccgtga tcgcgcccac tttcagtggg
    20521 gaatacagtt tttcagatga cataaaggct cccggtcgtc tggtgataaa aaatgcctgc
    20581 taaacggcag gcgtcgcaat aatgtttttt acatgggcca gcgcgttttc cagtggctcg
    20641 aaactgcgcg aaattttggc ctgcagattc gcgccaagcc acagtgcgta aagcacttgt
    20701 gcctgttgca gcggttcgcc acaaaaggtt aaacaatggt tctcacggcc attttccagc
    20761 gcctgagaga gcagggcgat cacgccgcga gcacctttat ccatcgcgct gcgcatatct
    20821 tctgacagat cgcacacttc ggcagagagt tttactgtca ggcaaccact gatggttcca
    20881 tgttggcaaa actggttcag tgtttgctgg taataagcca gtatgcggtc gcggtagtta
    20941 ccttcgccgg attgcagcaa ctcagtcagt cgctggtgat atgcggcgta atgacgctca
    21001 agcatggcaa cgccaaacgc ttctttagag cgaaagtagt gatagaagga ccctttcggc
    21061 acttcagcgg tttttagtaa ttcgcttagc cccatcccgg tgaatccacg ttgcaggcaa
    21121 agttgctcgc ccgtcgccag gagatgttcg cgagtatcat gttcggtgtg tttgttcatg
    21181 cgttggagtg tagtagacca gtcggtctag tgcaagcaaa gttgctactt tggacattaa
    21241 cagcttcaat aatggtaata atcttatctg aggagggcga agtggcggag caattagagt
    21301 tctttcccgt ccagagcccg tgccggggaa tttgccagtc tgacgaacgc gggttttgtc
    21361 gcggctgttt tcgtagtcgt gatgagcgtt ttaactggaa taaaatgagc gatggcgaaa
    21421 aacaagaggt gctgcgcctt tgtcggcagc gattaatgcg caaattacgc gcaaataagc
    21481 cagcgtcatc agacgaaccg gagcaaccat cactcttttg aacctaatct tgcgtatact
    21541 cctctcatat ctgataagag gaagcgatta tggttcagcg tattactatt gcgccgcaag
    21601 gcccggagtt ttcccgtttt gtgatgggct actggcgatt gatggactgg aatatgtccg
    21661 cccgccagct ggtcagtttt attgaagagc atctggatct cggcgtgacc accgtggacc
    21721 atgctgatat ttatggtggc tatcagtgcg aagcggcgtt tggcgaggca ctgaaactgg
    21781 cacctcacct gcgtgaacgg atggaaatcg tcagtaaatg cggtatcgcg acgaccgcgc
    21841 gtgaagaaaa cgtcattggt cattacatca ctgaccgcga tcacatcatt aagagcgccg
    21901 aacagtcgct aattaatctc gcgaccgatc atctggattt gctgttaatc caccgaccag
    21961 acccgttaat ggatgccgat gaagtggcgg acgcgttcaa acatctgcat cagagcggca
    22021 aagtgcgtca ttttggcgta tcgaacttta cgcctgcgca atttgccctg ttgcaatcac
    22081 gtctgccgtt tacccttgcc actaatcagg tggaaatatc cccggtgcat cagccgttac
    22141 tgctggatgg cacgctcgac caactacaac aactgcgtgt tcgtccgatg gcgtggtcct
    22201 gccttggtgg tggtcgtctg tttaatgatg attatttcca gccgctgcgt gatgaactgg
    22261 ctgtggtggc agaggagtta aacgcgggct cgattgaaca ggtggtttac gcctgggtat
    22321 tacgtttacc atcgcagccg ctgccaatta tcggttcagg taaaattgag cgcgtacggg
    22381 cagctgtcga agcagaaaca ctgaaaatga cccgtcaaca atggtttcgt atccgtaaag
    22441 cggcactggg gtacgacgta ccgtaagcac ttttaggaat agccgccgtt caaaaatgtg
    22501 tcactggttt acacttattc aggaatgcac aatgaacgga ggtcctatga aacgttttag
    22561 tctggctatt ctggcgctgg ttgttgcaac cggcgcacaa gctgccagtg aaaaagtcga
    22621 gatgaacctc gtcacgtcgc aaggggtagg gcagtcaatt ggtagcgtca ccattactga
    22681 aaccgataaa ggtctggagt tttcgcccga tctgaaagca ttaccccccg gtgaacatgg
    22741 cttccatatt catgccaaag gaagctgcca gccagccacc aaagatggca aagccagcgc
    22801 cgcggaatcc gcaggcgggc atcttgatcc acaaaatacc ggtaaacatg aagggccaga
    22861 aggtgccggg catttaggcg atctgcctgc actggtcgtc aataatgacg gcaaagctac
    22921 cgatgccgtc atcgcgcctc gtctgaaatc actggatgaa atcaaagaca aagcgctgat
    22981 ggtccacgtt ggcggcgata atatgtccga tcaacctaaa ccgctgggcg gtggcggtga
    23041 acgctatgcc tgtggtgtaa ttaagtaatt aagaggccag cgtaccttgc ggtggtgctt
    23101 gctcaagttg cgaaagcgag cagtacagcc gccagacaat tgccgccagc tcacgggcgg
    23161 caggttgatg atgacgggca aggctgtcgc aaatccgctg taattcttca agtgtggccg
    23221 ccagtgattt ttgctgaacg ccacgctcac tcatcactcc ccgcaacagt gaaatacagt
    23281 tatcccgtac tcgcgataac ggatcggaac gcgattccca gtcgcgcaat tgccagacaa
    23341 catgagaaca gttcagcagc actacacccc agcgtaataa ccaacggcga gccagcgcat
    23401 cctggctgtt actcaactga ctgacgtgat gataagtgag cgattcaaat tcgctttcac
    23461 tcagtgttgg atggcggctt agctgatcga caaaatcccg gcgcagcgcg cgaatatggc
    23521 ggcggctttt acgagcatcc gatcctggac gcagaatggc gaacgctaac cacgccaacg
    23581 cgacgccaac gatttttgcc agattatcgt taagaaaatc agcaaaatca tacaccgggg
    23641 gattagtgac agcgataaaa gaacccataa aaacaatcag ttgcccccac agtgcggcaa
    23701 attttggcat ctgcaattta agaagctgca ttgtcgccag cagtggaaag agaaacagta
    23761 aaaattgcca cagatcgcta atctggacca tcagaccaaa tttgaccaca aagctgaata
    23821 gcgaaagtaa caccagcgtg cgcatcagaa gtgacaacga cttaaacggt gctgcgacgg
    23881 cggagtagag tacgcagcta attgctgcca gcgttaatgc attggcaccg gcatcccatt
    23941 gcgaagcaat actccatgcg ccaatcatca tcaacgtaca aaatgtacgc agcccgctcc
    24001 acatagcttc ggcgttatcg gtatgacgag ccaggccgga tgtccgtggg agtctggtat
    24061 gatcatctac accgctttgc agacgatgta attcctgact actttgcaga taaaggcggc
    24121 aaaaataacg tagtcgctgc cagaaggcga cgtgccgata gtcggcgacg ttggtcgggc
    24181 gtagcggggc gataatacgt gcgacggtgt aaacatctgt ttgcgaactg gcgagcgccg
    24241 tcagcaactg ttcgagaatt tctcgtgtgg cacctggcgg tgagggccag ttgagcaaca
    24301 tacgtcgcag gctggagatg acactggtca tacgtaattg ctggtggagc agcgcattaa
    24361 ggcgcgcgtt ttgctggcga aaacgatagt ggctccagaa agcctggata cgcagcaaat
    24421 tcatggtcag tatctgccca atcacccctt catgtgctgc acgaatggca tcggttgttt
    24481 caggctgcca gagtaaactg gcatgttcca gtaatcgggc gtgcatgttt ttcaatgcgg
    24541 ttaaaagggc agtagcatcg gaactgctcg gcaggatcat catcatcatg ccgccgcaca
    24601 aaataccgac tattacctcg caaacgcgcg cctgagcgat atcccacagc tggctggcct
    24661 cagtaatatt aaccatcgga aaggcgatga tggcagccgt gtagcccgcc agttgaaatg
    24721 catacgcgac gttattcgtg aagtgcgcac aggcccaggt acaaaagcca agccacgccg
    24781 acatgctcaa tagaaaaaac cacggctcat tgagcgtatg cccggcaaga agcagtgccg
    24841 caatggctcc gagcaaactg ccagcgatgc gtccgaggct tttgctgata acaccgccaa
    24901 cggtgggaaa gctaaccact gcagccgagg tcatcgccca atagggttca tccagattta
    24961 aataataggc aaccgtcagc gccagacaca tggcaatggt attgcgtaac gcataacgcc
    25021 attgcgccag cgtggccctg aaccagggca aattgcgcaa ggaccatgac gatgcgttca
    25081 ttattgacct acggcaatgc tacaggtggt gcccgacacc aacgtgacat cgcctgggac
    25141 tttatccagc gcaaagcgga cgggaacgcg ttgggcgagt cgaacccagg ggacgttagg
    25201 tttaacatcc ggaataaggc ttgagtcact ttcaacgctc tgatcataaa tcgcccgacc
    25261 gatactggaa acgtgaccct gtaacgtttt gttatcacta tagagggtaa tttgtgctgg
    25321 tgcaccttcg cggatatggc gcaacttggt ttcttcaaaa taaccaatga cgtaaaacga
    25381 gtggctgtcg acaagggcaa acagcggttt cccggtatca gcgtaatcgc cgatgcgggt
    25441 agtaaggtta gtcacccatc cactcaccgg ggcgcgaatt tccgtttgcg ccagttgcca
    25501 ttgtgcctgt ttcagcgtcg cctgtgcggc atcaacactg gcctgcatcg ctttaacatt
    25561 gaggttagcg gtatcgagtt cttcggcaga aataaaattt tgtgagagat gacgacgacg
    25621 attcgcttcg ttattggctt ttgcgaggtc agattgcgct ttcgccagct gagcctgtgc
    25681 gttcagctcg gcgatctgaa agggcgtttt atcgatcgtg agcagaagat cccccgcgtt
    25741 aaccagctgg ttgtctttta tattcagctc aacaatacgt cccgacacct gtggggtgat
    25801 agaaacctgt tctgcgcgta ttttcccgtc gcgtgtccac ggagattgca tgtaataatt
    25861 ccacagccac catccggcaa gaaccgcaac taccgctaca atgattgttg agaaatactt
    25921 aattgtttta attgacatag ttaccacgca atcagtattg ccagagcaag gcaaacgcaa
    25981 atcgcaaaca gcgataaatc cattaacaag ggatgccaga tgtcaccggc gtagatccag
    26041 ccacgaagca ggcggtgtac gacaagccag atgacgaatc caaacgcgaa tgctttgaaa
    26101 aacggaggaa agtagacgga cgcaccgaac accagatctt gtaagggcaa tcctgttgca
    26161 ttgagcataa acttcacaaa gtagattcct ttacgaccga atatattgcg ttagattaat
    26221 aaatattctt taagtgcgaa aaatttacgc gcaatttctg aaaaatatgt ctgacggtaa
    26281 ccaaatgcag caatacattt gttttagcaa tacaattgct gcacactatt ctaaaagccg
    26341 cataatatct tagcaagcta attataagga gatgaaattg gaatcgccac taggttctga
    26401 tctggcacgg ttggtgcgca tatggcgtgc tctgatagac catcgcctga aaccgctgga
    26461 gttaacacaa acccattggg ttacgttaca caatatccat cagttacctc cagaccagtc
    26521 gcaaattcaa ctggcaaaag cgattggcat cgagcagcca tcactggtcc gtactctgga
    26581 ccaactggaa gaaaaagggt taatttcgcg tcaaacttgt gccagcgatc gtcgggctaa
    26641 acgtattaaa ctgacggaaa aggcagagcc gctgatcagc gaaatggaag ctgttattaa
    26701 caaaacccgc gcggaaatat tacatggcat ctccgcagag gaactggagc aactgattac
    26761 gctcatcgca aaacttgagc ataatatcat tgagttacag gccaaagggt gaaatgaagg
    26821 gggcgtgtgg tcagtaacct gaccacacgc aaacttattt agcgcggaga aacggtcacc
    26881 tgactgccat tgctggccag tacgacacgt tggcccggag agaaacgagt gttgccttgt
    26941 ttctgtacca ccatgatggt attaccatcg tctttacgaa tttccagctc gacaccctgc
    27001 gttttgttca ttgcactctg tacgccctga ccagctacgc cacctgcaac agcgcctgct
    27061 gcagtagcca gagaacgccc ggttccgcca ccaacagtat tccccaggaa accaccaaga
    27121 acagcaccgc caattgcacc gataacgttg gaatcatcac cgccctgaat ctgtaccgga
    27181 cgtacgttaa cgatggtgcc atagctgaca ttctgtactt gtttcgcttc agaagcggta
    27241 taaacatccc ctgacagggt gtcgttatta acacaaccga caagagacag acctaccatt
    27301 gaaacaacca atacgcgttt aatcattgaa aaatctcctg ttcaccatga aacgccacgc
    27361 aagcatccct catggtcaaa gtatatggca tatgtgaatc catggttaca tgttctacca
    27421 aatatgagca aatcataatg aaagtaggat caaccaatta taaacaaaac attcatgatg
    27481 attattgatt tgaagataat gttttactac caacggtaaa aatcggtcat tccgcatggt
    27541 attcacgaaa agtttatgtt tgagtggtgc gcaaacgtca gattgaaaaa ggatgaacta
    27601 tgaaatcggg ccgctttatt ggcgttatgt caggcaccag ccttgatggt gttgatgttg
    27661 tgttggcgac aattgatgaa caccgggtcg cacagctggc aagtttgagt tggccgatcc
    27721 cggtatctct gaaacaggct gtactggata tttgccaggg ccagcagctt acactttcgc
    27781 agtttggaca gcttgatact caactcgggc gactttttgc tgatgcggtc aatgccttgc
    27841 ttaaggaaca aaatttgcag gcaagagata tagttgcgat cggttgtcac ggtcaaaccg
    27901 tctggcatga accgacgggc gtggcaccac acactttaca gattggcgat aacaatcaaa
    27961 ttgtggcacg caccggaatt acggttgtcg gtgattttcg ccgtcgcgat attgccttgg
    28021 gaggacaagg cgcaccgctg gtacctgcgt tccatcatgc gctgctggct cacccaaccg
    28081 agcgacgaat ggtgctcaat attggcggca tcgccaatct gtcactgctc attcctgggc
    28141 agccggttgg gggctacgat accggtcctg gtaacatgct gatggatgcc tggatctggc
    28201 gtcaggccgg taaaccttac gataaagatg ccgagtgggc acgggcgggt aaagttattc
    28261 tcccactgct gcaaaatatg ctcagcgacc cgtatttctc gcaacctgca ccgaaaagca
    28321 ccggacgcga atactttaac tatggttggc tggagcgcca tttgcgccat tttccgggtg
    28381 ttgatccccg agatgtgcag gcgacactgg cagaactcac cgccgtgacc atttctgaac
    28441 aagttttgtt gagcggtggc tgcgaacgat tgatggtatg tggtggaggt agtcgtaatc
    28501 cgctactcat ggcgcgtctg gcggcattac tgccaggcac agaagtcacc accaccgatg
    28561 ccgttggcat tagtggcgat gacatggaag cattggcttt cgcctggctt gcctggcgga
    28621 cgctggcggg attaccagga aatctgcctt ccgtcactgg cgcaagccag gagacggtac
    28681 tgggggctat tttccccgct aacccgtgat atcagagtta actgaatttt tcttaccgcg
    28741 tctgccgtta cacttggaac gttagggagg gcgtattgcc ctccagacca ggaaagtctt
    28801 cgggatatga ctatgaaaaa actgttaatt atcattttgc cggtccttct ctccggctgt
    28861 agcgccttta atcagctggt tgagcgcatg caaaccgata cgctggaata ccagtgtgat
    28921 gaaaaaccgt tgacggtcaa actgaataat ccgcgccagg aggtcagttt tgtttacgat
    28981 aatcaactac tgcatctcaa acagggcatt tcagcctctg gcgcgcgtta cactgacgga
    29041 atctatgttt tctggtcgaa aggcgatgaa gcgactgtct ataaacgcga ccgcatcgtc
    29101 ttgaataact gtcagttaca aaatccacag cgttgagatt tttccagggg cggcgcacaa
    29161 tagcgtcacc cactgacaat ccgtaaagaa aaccatgtct gataacgacg aattgcagca
    29221 aatcgcgcat ctgcgccgtg aatacaccaa aggcgggtta cgccgccgcg atcttcccgc
    29281 cgatccatta accctttttg aacgttggct ctctcaggct tgtgaagcca aactggcgga
    29341 ccctaccgcg atggtggtcg ctaccgtgga tgaacatggt cagccttatc agcgcatcgt
    29401 tttactcaaa cattacgacg aaaaaggcat ggtgttttac accaacctcg gcagccgtaa
    29461 agcacatcaa atcgaaaata atccgcgcgt tagcctgctg ttcccgtggc atacccttga
    29521 gcgccaggtg atggtgatcg gtaaagcaga acgactttcg actctcgaag tgatgaaata
    29581 ttttcatagc cgcccgcgtg atagccagat tggtgcatgg gtttcgaagc agtccagtcg
    29641 catttctgcc cgcggtatcc ttgaaagtaa attcctggag ctgaagcaga agtttcaaca
    29701 gggcgaagtg ccattgccga gcttttgggg cggttttcgc gtcagccttg aacagattga
    29761 gttctggcag ggtggtgagc atcgcctgca tgaccgcttt ttgtaccagc gtgaaaatga
    29821 tgcgtggaag attgatcgtc ttgcaccctg aaaagatgca aaaatcttgc tttaatcgct
    29881 ggtactcctg attctggcac tttattctat gtctctttcg catctggcga aaagtcgtgt
    29941 accggcaaag gtgcagtcgt tatatacatg gagattttga tggcaagcag taacttgatt
    30001 aaacaattgc aagagcgggg gctggtagcc caggtgacgg acgaggaagc gttagcagag
    30061 cgactggcgc aaggcccgat cgcgctctat tgcggcttcg atcctaccgc tgacagcttg
    30121 catttggggc atcttgttcc attgttatgc ctgaaacgct tccagcaggc gggccacaag
    30181 ccggttgcgc tggtaggcgg cgcgacgggt ctgattggcg acccgagctt caaagctgcc
    30241 gagcgtaagc tgaacaccga agaaactgtt caggagtggg tggacaaaat ccgtaagcag
    30301 gttgccccgt tcctcgattt cgactgtgga gaaaactctg ctatcgcggc gaacaactat
    30361 gactggttcg gcaatatgaa tgtgctgacc ttcctgcgcg atattggcaa acacttctcc
    30421 gttaaccaga tgatcaacaa agaagcggtt aagcagcgtc tcaaccgtga agatcagggg
    30481 atttcgttca ctgagttttc ctacaacctg ttgcagggtt atgacttcgc ctgtctgaac
    30541 aaacagtacg gtgtggtgct gcaaattggt ggttctgacc agtggggtaa catcacttct
    30601 ggtatcgacc tgacccgtcg tctgcatcag aatcaggtgt ttggcctgac cgttccgctg
    30661 atcactaaag cagatggcac caaatttggt aaaactgaag gcggcgcagt ctggttggat
    30721 ccgaagaaaa ccagcccgta caaattctac cagttctgga tcaacactgc ggatgccgac
    30781 gtttaccgct tcctgaagtt cttcaccttt atgagcattg aagagatcaa cgccctggaa
    30841 gaagaagata aaaacagcgg taaagcaccg cgcgcccagt atgtactggc ggagcaggtg
    30901 actcgtctgg ttcacggtga agaaggttta caggcggcaa aacgtattac cgaatgcctg
    30961 ttcagcggtt ctttgagtgc gctgagtgaa gcggacttcg aacagctggc gcaggacggc
    31021 gtaccgatgg ttgagatgga aaagggcgca gacctgatgc aggcactggt cgattctgaa
    31081 ctgcaacctt cccgtggtca ggcacgtaaa actatcgcct ccaatgccat caccattaac
    31141 ggtgaaaaac agtccgatcc tgaatacttc tttaaagaag aagatcgtct gtttggtcgt
    31201 tttaccttac tgcgtcgcgg taaaaagaat tactgtctga tttgctggaa ataatgcatt
    31261 aagtggaaag ggggagtgag aaatcactcc ccctggtttt tatacaggga acatgatgaa
    31321 aaatattctc gctatccagt ctcacgttgt ttatggtcat gcgggtaaca gtgcggcaga
    31381 gtttccgatg cgccgcctgg gcgcgaacgt ctggccgctg aacaccgttc aattttctaa
    31441 tcacacccaa tacggcaaat ggactggctg cgtgatgccg cccagccatt taaccgaaat
    31501 tgtgcaaggc attgccgcca ttgataaatt acacacctgt gatgccgtat taagtggcta
    31561 tctgggatcg gcggagcagg gtgaacatat cctcggtatc gtccgtcagg tgaaagccgc
    31621 gaatccgcag gcgaaatatt tttgcgatcc ggtaatgggt catccggaaa aaggctgtat
    31681 cgttgcaccg ggtgtcgcag agtttcatgt gcggcacggt ttgcctgcca gcgatatcat
    31741 tgcgccaaat ctggttgagc tggaaatact ctgtgagcat gcggtaaata acgtcgaaga
    31801 agcggttctg gcagcgcgcg aactcattgc gcaagggcca caaattgtgt tggttaaaca
    31861 cctggcgcga gctggctaca gccgtgaccg ttttgaaatg ctgctggtca ccgccgatga
    31921 agcctggcat atcagccgtc cgctggtgga ttttggtatg cgccagccgg taggtgttgg
    31981 tgatgtgacg agcggtttac tgctggtgaa actgcttcag ggggcaacgc tgcaggaggc
    32041 gctggaacat gtgaccgctg cagtctacga aatcatggtg accaccaaag caatgcagga
    32101 atatgagctg caagtggtgg ctgctcagga tcgtattgcc aaaccagaac attacttcag
    32161 cgcaacaaag ctctgaaata tctcatttcg gcccacaacg acctgtgggc cgatggctat
    32221 tactttaagc cttccgctga cagcgcgtct tgtacttccg gacgttcagc catacgttgc
    32281 ataaatgctg caatgtgctc taacccttcc agattcagtt tcaccgcgta tgcccagcgc
    32341 agaaccgtaa acagacaggc atcagcaatt gtaaatcttt gcccgcagat ccagtgctca
    32401 tccttcagtg cctcgttcac atattgcagc ttcttctcca gctgcgcgcg aactgtcggt
    32461 ttgtactctt ccggtgtatc agggcgaaac agaggtgtga aacctttatg cagctcggtg
    32521 gcgatgtaat tcagccattc gatggtttta tagcgggaaa tactgtttac cggtgccagc
    32581 aactggcggt cggggacgct gtcggcaaga tactgcataa tcgctacgcc ttccgtcagc
    32641 aaagtaccgt catccagcag caatgcaggc acctgcccct tagggttaac ggcaaagtaa
    32701 tcgtcaccgt tttcgagacg ttttttcatt aaatccacac tgacgagggt aaaatccttt
    32761 ccgctctcac gcagggtgat atgggaagcg agagagcagg cacccggttt gtagaacaat
    32821 ttcatcggta actccttttg tctgtggttt aaagtatggt agtgcgttgc tgaacaaaaa
    32881 aaaagccgct aacgaaaagt tagcggcttg taaaagagtt tccctgaatt ttacgctacg
    32941 gctgctttcg ccgctttgtc tgcagcgtca tcctgcgtca tgcggtgcag tttcggcgcg
    33001 gtcagcagca tcagtactgc aataacggca gtagcgacac caatctgcaa gaatacgcga
    33061 ccatagactt ccagtgacat cagcggatcg gtaacgttat ccggcacagc catcataccc
    33121 gcaacataac caccaatcag gtttgcaccg gcagtggtca ggaaccagct acccataatg
    33181 aagcccatca gacgctgcgg aacgagttga gcaaccattg ccagacccag accagagatc
    33241 atcagttccc cgatgctctg caggccatag cttgcgacca gccagcttac agacacgata
    33301 ccagcgtcag acgcgaattt cgcacccagc ggcagaatca ggaacgcacc agaacacatc
    33361 accatgccga ttgcaaactt ggttggcatc ggcagggtat cgcccatctt gttatagata
    33421 gcggccagaa tcggactacc gatgatgatc cagaacgggt tcagtgcctg atactgctca
    33481 ggttctacgg ccagacccag aatggagtgc tcaacgttac gaatcgcaaa gaagttcagt
    33541 gacgttggca tctggctgta cagcacgaag aagataatgg cttcgagcat caggatgaag
    33601 gcaacgatca ttttacgacg cgcagcacct ttcatcgcga aggcttcttt accgaagata
    33661 accacgatac cgaaggcaac aacgcccagc gccatacgcg caacttcctg attgtgcagc
    33721 agccaggtgg cgatagcgat cagtgccaca acaccaataa tggtcagcag caggttacgg
    33781 tagttgatag gctcgaagtc tggttttgaa ccgtactgtt taacccagcg ttggcagaag
    33841 gcgaagttaa cgatagtgat cagcaggcct acaacgctca acgcaaacgc aacactccag
    33901 ccgtatttcg cggccagcca cggcgtagca atcatagaga agaaagagcc gatgttgacg
    33961 gacatgtagt acatggtgaa tgcaccgtcc agacgcgggt cgtttttctc atagcatgta
    34021 gaaagcagag aagacgggtt agctttaaac aggccgttac cgaccgcaat agccgccata
    34081 cccatataaa cgataccggc gtcgtgacca gaccaggcaa ccagagcata accaatcgcc
    34141 agcacaatag cgccgagcat aattacgcgt ttagtaccca gtaccttgtc acctaaccag
    34201 ccgccgatag cgaccagacc ataaaccagg gcactaaagg aagagaaaag ggtgattgaa
    34261 tccgcttcag acatacccag ttgtttaacc aggtaaacag ccataattcc ttgtaggccg
    34321 taataaccaa aacgttccca taactcaatc gagaagatga gatagaacgc cttcggttgt
    34381 ttgaaagcgt tcaaactgac gctttcagtt ggtttttggt ttgcagtgga cacttttacc
    34441 tcttttttta catcccatat taacgggggt gctttctcgc gttatgtata aaaaacatac
    34501 gcgcaattgt tatagtggga ggggaaacgg caggtaatgt tcactatctt gcactttcag
    34561 acaagtcctt tgtaataatc tgttacatat aactgaggcg gggaattcaa ccattccggg
    34621 aaatgttatc cagcgttaaa tttttcaaaa aacgtaacgg cagatttttt cactgcactg
    34681 agaggggggt gatggcttaa cggcgatatg ttctgctatt tagcgttttt actagtgaga
    34741 tagtccagtt tctgaaaaat agccagtgta atgttttgta ggtcaatatt tgttgcgtgt
    34801 gtaaatttaa atgattttaa cctgattctt gcaatgtttt tacattgtga cagcatcgtg
    34861 atcttgatca cgaatgaata gaaaatttcg ctattaaaaa aacaattaac ctgcattttt
    34921 ggttatccgc aaacggatta cctgatgata acgctaagca atggcatcat tgacgttaaa
    34981 aagatgtttt aaaagaggat aaagaaaggt tatcaatggg gtaatcggtg ttaccccttt
    35041 tcttcagatg tcaactttct ctttgtattc acaaagatct tcaataatac aagagccaca
    35101 gcggggcttg cgggcaatgc aggtataacg cccgtgcagg atcaaccaat ggtggcagtc
    35161 gactttaaac tctgctggaa ccactttcag tagcttttct tctacctgtt cgacgttttt
    35221 ccccggcgca aattgagtac gattacaaac gcggaaaatg tgcgtgtcga cagcaatagt
    35281 cggccagccg aatgcagtgt ttaatacgac gttggctgtt ttacgaccta cgccgggcag
    35341 ggcttcaagc gcagcacgat cttccggaac ctcgccatta tgctgctcca gcaagatacg
    35401 gcaggttttg atgatatttt ctgctttgct gttataaagc ccaatcgttt taatataggt
    35461 tttcacccct tcaacgccca gttcaagcat cgctgcaggc gtattcgcca ccgggtagag
    35521 tttcgccgtc gccttattaa cactgacatc ggtcgcctga gcggaaagca gtacggcaat
    35581 cagcaattca aaaggcgaac tgaaattaag ctcggtggtg ggatgaggat tgttctcacg
    35641 caggcgagtg aggatctcca ggcgttttgc tttattcatc agacattccc tgtttcaccg
    35701 tttggcaatg cacgttctgc agctgcttca gcacggcgct ttttcattct ttcatcaatc
    35761 aggtattttc ctgccagcat cagtcccagg ccaataaatg cacctggtgg cagcatcgcc
    35821 agcaggaaag gggagtcggt gtggaaaatc tccacgcgta atacttttgc ccagctacct
    35881 aacagcgcat ctgcaccgtc aaacaatgtg ccattgccga taatttcgcg tagtgaaccc
    35941 agcacgaaca tggcgcaggt tgcgcccata ccaattgaaa agccgtccag tgccgaaagc
    36001 gccggacctt ttttggcggc gaaggcttca gcgcggccca caacgataca gttagtgaca
    36061 atcagcggaa taaaaatccc taatgattga tacaggccaa aggcgtaggc gttgatcagc
    36121 atctgtacag cgctgaccac cgaggcgatg atcatcacgt aaatgggaat gcggatctcg
    36181 gctggcgtcc agtgacgcag cgtcgaaatg gtcaggttgg tcagcgtcag taccagcgta
    36241 gtcgcaagtc ctaaacccag agcgttagtg gcagtggacg tgaccgccaa cagaggacaa
    36301 aggccgagca actggaccag cgcagagttg tttttccaca acccctgaac aataacgtct
    36361 ttaatttcgc tcacgcttta ttctccacag gcaggaagtt gagaaagttg tgccggtaac
    36421 gtctgagcgt acaatccggc gcgttttacc gcattaacca ccgcgcgggg agtaatcgtc
    36481 gcgccggtga actggtcgaa atcaccacca tctttcttca tcgcccagtg cgcatcatct
    36541 gcaccactga tttttttacc cgcaaaatgg gtgatccagt cagaaaggcg cagttcgatt
    36601 ttatcgccaa gccctggcgt ttcgtggtgc tctgtcacgc gcgtgccaag taccgtgccg
    36661 ttaaaatcgg ctcccaccag cagctgaatc gcaccggaat agccatctgg cgcggttgct
    36721 tccagaacgg cggctaccgg tttgtcatcc tgtttggcga tgtaaacccg atgctcacct
    36781 ttacctaact ctggcgcagt taccagatag caactctgtg ccagcgcatt gttatagcgt
    36841 tcggctggca gcacctgatc aaataacgcc ttttgttgca gactggcctg ttcagcaatc
    36901 gtcgttttgg tcatctggtt gatggccgca gttaaccctg ttgaacccgc tgcaaatagc
    36961 gccaacgtaa tgccgtgttt tcggatagtt ttcagcatgg tttacccttt gcgatggccg
    37021 tagacgcgcg gacgcgtgta gtaatcgatc agaggaaccg tgatgttcgc cagcaggacg
    37081 gcaaaagcca cgccgtcagg atagccgccg aaactgcgga tcaaccagac taataagccc
    37141 gcaagcgcgc cgaaaataag acgaccacga ttggtcgtag aagcggtaac cgggtcagtc
    37201 aaaataaaga atgcgccgag catggtcgct ccagacagca gatgaatttg cggtgctgcc
    37261 agtgtttctg gtgagaacaa ccagcccaac attgcgcata acgccagcgt tactaagaag
    37321 ctgaggggaa tatgccagcg aatcgctttc tgccatagca accatacgcc gccagccagc
    37381 caggcgagat ttacccattg ccaaccagcg cccgccagaa taccgctgta gatcggatat
    37441 tgcataatct gttcaaccga atgaccggca cggacagagg ttttaaatgt atccagcggt
    37501 gtcgcctgac taatgccatc aatacctaag cgtagtgtgt tcatatcacc accactggcg
    37561 gtatgaccgc taaaaataac ctggatggcg tcgataaaac cagggatgtt gaccgcaatt
    37621 tcatgtggcg gtaaccagct ggtcatctgc acggggaagg agatcagtaa gaccacataa
    37681 ccaatcattg ccggattaaa cgggttttgt cccagaccgc catacaactg tttagcgatg
    37741 atcaccgcaa acaccgtacc cagcacgacc atccaccatg gcgcgagggg gggaatactt
    37801 accgccagca ataagcctgt cagcaatgct gagttatctt tcaacgttgc ggctaccgac
    37861 tgcttgcgta gtttgagtac gagagcttcg gctaacagag cactaaccga tgccaacagg
    37921 atctgaacga gagtacccca accaaaaaac cacagttgcg ctgcgattcc tggcacggct
    37981 gcgagcaaca ccaacagcat aatgcgcgat gtctggcgct ggttatgggt ataaggggag
    38041 ctagctattc tgaataccat ttagtcctcg tttacaacct tctgctgggc ggcttttttg
    38101 gcctgagcgc gggcaatagc cgcggcaact gccgctttgc gcggatcaac ctgttcttct
    38161 ggtaccgcat tagcctgttg ctgttccagc ttgcgtgctt tggcgcgtgc aatagccgct
    38221 tcgacggcag ctttgcgcgg atcaacctgt tcttctggct ccgcattagc cggttgctgt
    38281 tcccgtttgc gcgctttggc
//
LOCUS       DACAOP010000038        37947 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.038, whole genome shotgun sequence.
ACCESSION   DACAOP010000038 DACAOP010000000
VERSION     DACAOP010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37947
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.038"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(85..3102)
                     /locus_tag="IT892_002156"
     CDS             complement(85..3102)
                     /locus_tag="IT892_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element IS3000 family transposase"
                     /protein_id="HAP3135372.1"
                     /translation="MAFEERVQILSEAEQDELYGPPAFTSADQRFFFSLNDKELAIAK
                     SLRHRGQRYMLVVLLGYFKAKPVVLNPGFHQIKQDLKYVYQTVLPGPGCRPFNLTPKE
                     NERIYQRVFQLCNYQRWNVKDHGAALRDYLSQQARAWTAPRHLFDAANEYCSGQKIAI
                     PAYSTLQKIISQVVGDEQEHMAAHLERAMSRGLKQALAELVNGTGPLPFRQLRQSARN
                     FTGTELEKELIVYRHIQHWMPEVDLLLSTLSLSQKNLQHLAEKVDYYGAKLKRQTVGS
                     QWLYLLCYLQTRWQQALERIADGFVHHVRQTKQKAKDYAQEAVFKDWQKAAKNVSKAA
                     EVLHLFIDDSIDLQLPFATVRQQALSLLTKRDLESVCLFLNEQRRSVDEAMWQYCDEK
                     ESLRKGLLRELFLCLRFEGCDGTQHLAAALAKTQNELNGQDAQLQTADTRLLSKKSRE
                     FLLDGEGNILIDRYEWFLYQQIPDRLNGQLTLPDITKYRALDADLIDGEHWRKNKYTL
                     LQQSHFTKLAEEPEKLIKQMAMELDTRLYEVGEYLEQEDNRNIILRNPQGKRFWRLPS
                     ASKHHLVNNPFFQQIPTTGIADVLRMVDRDTGFIDCFAHVLGSQSRSRSHEYDLLAIL
                     VGNATNQGIYGMAQISDRTYDQLSTIQANYLRLETLNAANDNINNATAKLPIFRYYNI
                     QEDVIHASADGQKFEARRETFKTRYSSKYFGTQKGVSAMTLIANHAAINARVIGANEH
                     ESHYIFDLLMSNTSDIIPDVLSTDTHGVNHVNFALLDLFGYQFAPRYAQVGKVINDMF
                     DVKEDKEHRIQLCLKKPINTHRIAQHWDTIQRIAVSLKQRKTTQATLVRKLSEYKRNH
                     PLLEALTEYNRLVKANYLLCYIDDASLRNYVQRALNRGEAYHQLRRAVSSVNGDQFRG
                     SSDEEIQLWNECARLVTNAIVYFNSRILSQLLTSFEYQGDTKRIDIVKQASPVAWHNI
                     NLKGTYHFELSEKLPDLEELMRSIEGYLPVSEK"
     gene            3246..3791
                     /locus_tag="IT892_002157"
                     /pseudo
     CDS             3246..3791
                     /locus_tag="IT892_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001496645.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4767..4952)
                     /locus_tag="IT892_002158"
     CDS             complement(4767..4952)
                     /locus_tag="IT892_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004221702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135373.1"
                     /translation="MDRKSNSDSYQRWMIEKADKRERTQISMSFVKMKDVLFNVLAIG
                     TVLAALVVIFYEVQSSL"
     gene            complement(4910..5122)
                     /locus_tag="IT892_002159"
     CDS             complement(4910..5122)
                     /locus_tag="IT892_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004221700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135374.1"
                     /translation="MVTQSLADFGRYSYKPRPAFQDWIERLKTGERLPRGRYFVGKKP
                     GGRLVLIDELGGTWTEKVTVIHTNAG"
     gene            complement(5185..5460)
                     /locus_tag="IT892_002160"
     CDS             complement(5185..5460)
                     /locus_tag="IT892_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135375.1"
                     /translation="MHTTNAIILCLVSYPCIVAWVIYKNRFVDYLFLTLLACLGSIFS
                     VVLYKQPDYSLTIYQAVAVGYAAVIMPTVLVLSVVNIFMGKAERTCK"
     gene            complement(5478..5732)
                     /locus_tag="IT892_002161"
     CDS             complement(5478..5732)
                     /locus_tag="IT892_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135376.1"
                     /translation="MGHYTIRTNDDEDQAIKKAQEATGQASASKTFMTAILELQRNRD
                     EMAQLRRELAQEKARSQELVSSVKQFRSSLNNLFDLADNP"
     gene            complement(5842..6663)
                     /locus_tag="IT892_002162"
     CDS             complement(5842..6663)
                     /locus_tag="IT892_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HAP3135377.1"
                     /translation="MTRATERAYSELQQAFDFYNQRLFDGELPDCLITFQRGKNTMGY
                     FSYRRFVAADGSGRMIDEIALNPEYFPVYPLIEVMQTLVHEQCHMWQYHYGNPSRKTY
                     HNAQWAAKMESIGLMPSSTGRPGGAKVGQKINDYPIPGGRFQRVTLELFQGQFALSWF
                     DRFPVQVEQQKDMTAVIEQWRETLALAHQNAEAGIDIEAVLSMALLPSVSPQNGSHSD
                     DMAGSNDNDLSVAAFEDKPKRNKVKYQCRGCGAAVWGKAGLNIECGDCELAFIEN"
     gene            complement(6660..6839)
                     /locus_tag="IT892_002163"
     CDS             complement(6660..6839)
                     /locus_tag="IT892_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135378.1"
                     /translation="MTEKITDEELVDLLEALKRAHGMGVCSKAVKLAQRCADVFPAIV
                     AELQEYRNAAKRTSA"
     gene            complement(6856..7122)
                     /locus_tag="IT892_002164"
     CDS             complement(6856..7122)
                     /locus_tag="IT892_002164"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135379.1"
                     /translation="MISIAFASYILLALVVHLTLKQASYNGKVSSPAVNHACQQTSFL
                     QPVWPLIFASNITRSMPALGVKLPAKKIAAIKGVVYIICIVRYR"
     gene            7112..7762
                     /locus_tag="IT892_002165"
     CDS             7112..7762
                     /locus_tag="IT892_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HAP3135380.1"
                     /translation="MDIKPNSVIHLEPGETLPGYTNLKPVPDKYFDELKALINKLNTQ
                     SGNIYLKLKQMYAFLDRFNKEFVSTFTSCQKGCSSCCKMDVHLTALEATHIAQASKLT
                     ARDNPLTTGHESKCPFLSEKGTCSIYNYRPLLCRTYHVLTPPEMCNDLDAQVMQYGSQ
                     SANMGNHIYKTIAEWIYFQTYHCTGKLETKDIRDYFPYPREDIQRFLHHNPPRPFC"
     gene            complement(7800..8255)
                     /locus_tag="IT892_002166"
     CDS             complement(7800..8255)
                     /locus_tag="IT892_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS histone family protein"
                     /protein_id="HAP3135381.1"
                     /translation="MSENETFDATKKLLLNIRSVRVFARETSFEQLLEMQEKLNAVIE
                     ERREEAEREAAERAERERKRQELLQLIAGEGFSPEELLGLSEDAQKTRKKTLPKAPPK
                     YQFDENGETKYWSGRGRTPKPIDEALKAGRSLDEFLIKKDASSTAGDEQ"
     gene            complement(8267..10594)
                     /gene="topB"
                     /locus_tag="IT892_002167"
     CDS             complement(8267..10594)
                     /gene="topB"
                     /locus_tag="IT892_002167"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP3135382.1"
                     /translation="MRLFIAEKPSLAKAIFEGLGGNPNTEKKNGYFEHGSDVVTWCYG
                     HMLELYDPQDYDDKYSNWRYSDLPIKAVYPPKYKIKPESEAQTRIILSLIDKADSIVH
                     SGDPDDEGCLLVDEILGYAGNKKPVQRLLVADLNLAPVQKSLSNLQPNDKFRGMTLSA
                     LARSLCDQGFGYNMTRGCTLKGREKGYDGVLNVGRVQSAVLGLVNMRTLANQNHTESF
                     YYDVFASLSMNGHQIKAKYQTTDDDQIDEKKRLISEAQAAHIAGRVTGKDAIVTIATT
                     KPENSKPPLPLNLSTLQQLCAKRFGYSAKDTLDVMQGLYETHKLLTYPRSDNRYLSDE
                     HYYQAGDIATAIAATVPELASAIVDMDKGQKHKAFNASKIEAHHAIIPTTKSGAGIQL
                     NEKERNVYNLVSVYFIGLFYPDAIRNKTKIHFDIKGDTFTATQSVLVQKGWEALGKDS
                     DDEDETEDAGTDGFDLSLLKFNDSGLCESADVDKKKTTPPRYFTESTLLAAMTSAAKF
                     IDDPALRKALEAKDEGSSDRGSIGTEATRAGILEKLAANTGLISIEKEKGYSELVWKT
                     TKQGQEFCAALPPEITKPDISALWAEKQSQIKAGELTVEEFIKENDEYVQGLIDELDR
                     NGISISSNATPCPVCNNGFLRKRKGQNGFFWGCSCYPECKTTFPDKDGKPDMEAKSRS
                     EGSMSRLEAPCPSCSKEIIIRPKGFFCSGCEFKIWSEVSGKKLTQNQVETLIKKGKTG
                     EIKGFTSNKTGKKFDAAIVLQDKTTGKLGFQFSKK"
     gene            complement(10598..11860)
                     /locus_tag="IT892_002168"
     CDS             complement(10598..11860)
                     /locus_tag="IT892_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP3135383.1"
                     /translation="MGKLTLVEQALRLHKEYYGEDNFGTVVKDCDYYPKVAEIFINRK
                     NRKIYSNLDIEPVASTVVHTGSSPVMAKAGRIKKLMFKDGSGAYRIHLGQNEVVHIIR
                     FILNSKVRMEYAVGTTKSMSMLHNLCEAGRAKLNRSLPRKGIWKIGCYDGVYYHGKAR
                     KEEIENALRFSVHPKFNELENDFNQFFSDIDFYTRYGQSGMRKVLFTGPPGTGKTTIA
                     KALGAKYQDKYVFVYADDYFKDVCYAAAQKKIPVIIIAEEVDELYRADAGTLSFLDGA
                     DTPRNLAGTYVIFSTNYPNRIDPRIRKRPGRIDRIISVGAFRTKAAAACAKMYLPDDI
                     NIDLKELGAVLDRTTPAEIKEIINIAIGMIRGTKNELTVDVIKNARAFLKGTLDLSVQ
                     EAEEDIEEREEIFKKNGAQPDYSSYLED"
     gene            complement(11943..12437)
                     /locus_tag="IT892_002169"
     CDS             complement(11943..12437)
                     /locus_tag="IT892_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HAP3135384.1"
                     /translation="MRHFFNVLSFAVALLPATLCAAQIQGKVIRVLDGDTIEVKTLPA
                     KIVVYEVPIRVRLINIDAPEKKQPFGRWSTNQLKALLAGQSVTVSYTQTDRYGRVLGR
                     VVTANGTEANRQQVLKGAAWVYDRYNTDNSLPALQREAQTQKRGLWADSNPVPPWEWR
                     HKQN"
     gene            complement(12434..12760)
                     /locus_tag="IT892_002170"
     CDS             complement(12434..12760)
                     /locus_tag="IT892_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004208538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135385.1"
                     /translation="MKIINVPDARSVRIAGIEIIDSVKSVASVFTEILLFMVWFPAIV
                     YGLYRFVIVLWDASLKPQSLIEFINFMVELYSYVLPSLAVIAVALVVVLSIFKRLSAI
                     WEGRKQ"
     gene            complement(12846..13160)
                     /locus_tag="IT892_002171"
     CDS             complement(12846..13160)
                     /locus_tag="IT892_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135386.1"
                     /translation="MKKTVTTAVLLCAFAAGTAHAEEKADPNDPCAMVLCLAGKLDGS
                     SPAECDPMYKSFMSIRKKNKHGFLPDHTADARKKKLNECPAADAGTVSKIISSFGRLK
                     NF"
     gene            complement(13248..13640)
                     /locus_tag="IT892_002172"
     CDS             complement(13248..13640)
                     /locus_tag="IT892_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP3135387.1"
                     /translation="MKKMLMVSVLFLSACSSPPEPPQVDWEQNPETVNTQLMDWQPTY
                     SVIKSDKVNSSWVKVIHNFRPENRLYDDAVFYSVAHSDSVIVETSNGTDFFTAKNWLR
                     ANGANGVIQYRYKMNCFSCRTTSVYLSR"
     gene            complement(13637..15472)
                     /locus_tag="IT892_002173"
     CDS             complement(13637..15472)
                     /locus_tag="IT892_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP3135388.1"
                     /translation="MSLKLPDKGQWAFIGLVMCLVTYYTGSVAVYFLNGKTPLYIWKN
                     FDSMLLWRIITESNIRTDIRLTAIPSLLSGMVSSLIVPVFIIWQLNKTDVALYGDAKF
                     ASDNDLRKSKLLKWEKENDTDILVGAYKGKYLWYTAPDFVSLGAGTRAGKGAAIGIPN
                     LLVRKHSLIALDPKQELWKITSKVREKLLGNKVYLLDPFNSKTHQFNPLFYIDLKEES
                     GAKDLLKLIEILFPSYGLTGAEAHFNNLAGQYWTGLAKLLHFFINYDPSWLGEFGLKP
                     VFSIGSVVDLYSNIDRELILSKREDLEGTKGLDENALYHLRDALTKIREYHETEDEQR
                     SSIDGSFRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAEDMSLAYDFLNL
                     FFNFVVEVTLRENPDFDPTLKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIY
                     QNISQLNEIYGVEGAKTLMSAHPCRIIYAVSEEDDAKKISEKLGYITTKSTGSSKTSG
                     RSTSKSSSESEAQRALVLPQELGTLDFKEEFIILKGENPVKAEKALYFLDPYFMDRLM
                     MVSPKLTELTASLNKTKKVLGVKGLKYPSKEKMLSVGELESEVLL"
     gene            complement(15475..16509)
                     /gene="virB11"
                     /locus_tag="IT892_002174"
     CDS             complement(15475..16509)
                     /gene="virB11"
                     /locus_tag="IT892_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="HAP3135389.1"
                     /translation="MKDAENRHIVYEIIDEYFHHWLNEVDGLTEIAVNRPDELFVKVS
                     GKWQQHELKMDFKDCMSFAGAISDYHDGGSVTPEYPLRSVTLPGGERVQIVIPPATER
                     ETVSITIRKPSSVFIDHDTFVKQGFYSRLNQGGKFRDKEDELSSMFKDNCFEQFVPEC
                     LVKGKTMVFCAGTGAGKTTFANACLQYIPHHLRCISIEDTDEAKFRFHKNHVKLYYPS
                     EGESSTVSSASLLRSGFRMNPDRILMTEVRGAEAWDFLKGSSSGHAGNLTTVHESTPE
                     DAVLGLVQRCYMNPECQNLPYNIILRRVLSNVDVIMSIKYIDEEDNRFASGIYYRDIH
                     FQEYFEKLKE"
     gene            complement(16506..16703)
                     /locus_tag="IT892_002175"
     CDS             complement(16506..16703)
                     /locus_tag="IT892_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000629109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP3135390.1"
                     /translation="MITLDIKEFSMLLGIRESEIYHHIRKGIPINGVPFPKPLKQIKT
                     HRFNYEEVMRFIEDLKGKGEL"
     gene            complement(16705..17919)
                     /locus_tag="IT892_002176"
     CDS             complement(16705..17919)
                     /locus_tag="IT892_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="HAP3135391.1"
                     /translation="MSEQENKIPTAVEIEQALRERHQKEIEQNDKTDKGDEDDGKSVK
                     RLGIEKLKKSRKGLVIIVAAFLLLAAGVSVYYIPSIIRAMSSGDDKPASNAVSTGSVK
                     RATGLSDDVDPFNTREEPAKTEERKESSGKAETPPEKVQQNFSRALDVAYGGSSSASS
                     NSGGSSSTASNTRNEGDGSDKQAEVQPVNAGQPAQLSKITRVPYDPNLFIPENTAIKC
                     SLDRRFISDLAGKLVCTINEDVYSANRNVKLIEKGTAAYLMYKTGTFNHGQGAVFIAA
                     TKLRTRKEPFIDIPLIDTQAAGALGEAGASGWIDTHFADRFMGAMMVGMIPDVAQAAS
                     GAAKSNKDNQTDYTANSRQAFADIAREAFANSVNIPPTLYKNQGEIITLIVGQDLDFS
                     SIYKLKMVGTRR"
     gene            complement(17916..18845)
                     /locus_tag="IT892_002177"
     CDS             complement(17916..18845)
                     /locus_tag="IT892_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000783379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="HAP3135392.1"
                     /translation="MKMNKGALIVALLLVSHVCHAAVTPAASRFDPRNQIVSYNPQNT
                     TVINSAVGYTTTLVFDEDETVISARTGFPQGWEVNKEDNLVYLEVKPVKQTVQKNSTD
                     DNGNQSSEVVSVALDPENDLERWRTNLFVRTTKRNYSMELNARTFRQPDKIAFVVNYQ
                     YPQERRKEQAEIEKKRIEALNKRQEEQAINRSLENAKSPKNWDYWKRVADGSQSISPD
                     YAYDDGRYTWFGFSPLKKIPSVFVMSGEQETLTNPVVKNSGSFTVVGVPVDQRFVLRM
                     GNQVVGVENRGFGKVRLPAGDTVSPNVEKEVIQ"
     gene            complement(18851..19579)
                     /locus_tag="IT892_002178"
     CDS             complement(18851..19579)
                     /locus_tag="IT892_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004199085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HAP3135393.1"
                     /translation="MGFKLSGLKLPGFNKKKEVTDSSTTFEEKNVLMQEKMNRIYKFG
                     GIAGIAVGVLSLLALNGALPLKSTVVEAYLINGVTGVAERLTSVKKENLSENEALAKY
                     FITQYVKRREGYNYFSLQHDYDYVLLYSAENVATDYNALINGNQSPKVIYNKAEKTAS
                     VQDNPSVIISPSSRRDDKDMGAYIRFKLTIRNVATGQDDYEYWNVRLTYRIEPQVEMA
                     SGDRNNNPLKFVVTSYVRDKEVKG"
     gene            complement(19774..20829)
                     /locus_tag="IT892_002179"
     CDS             complement(19774..20829)
                     /locus_tag="IT892_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HAP3135394.1"
                     /translation="MATSRYFQAAHDVIVKTLDQSLTGQLDNFSSIASQLGKYGISIY
                     ILWYAYTTIVGKQKTAVQDFLWNLCRFWLILVFVKNMGGWLDSATQAIDGLKETFAGG
                     DPWKWVDELWEKVQQVAAYLMSKDTSKYVKTDGAIASLLTYAGGIIALLLTSIVYLAA
                     EVTIKILTITAPLFIICLSFGFLRQMFNSWLQLIFSSCFIFLFCGLAIKAGMTFLNGI
                     LTISIANADELNLISTGAQAGVAGAFMAWIIWQAKTYASQLAGVGVEGAMQGAAAMGI
                     GAGVFGASRMGRNLLGMGKNAGIGAWKGVRRQDGGFNQSPGVSGKLGNLTGQGVNIGA
                     KRLRQAAIDAAKKKYGG"
     gene            complement(20841..21098)
                     /locus_tag="IT892_002180"
     CDS             complement(20841..21098)
                     /locus_tag="IT892_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="HAP3135395.1"
                     /translation="MKKYGLVAALGLTFFLTGCEEVKSVDWWQSHVDDATKKVAECKK
                     SGSDSENCKNAKEGLFRYKQLHPKHVDYKDAFKNVLGKDGS"
     gene            complement(21108..21878)
                     /locus_tag="IT892_002181"
     CDS             complement(21108..21878)
                     /locus_tag="IT892_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein"
                     /protein_id="HAP3135396.1"
                     /translation="MKKHIVAALIASVTVISGAQAGVPVAIDANPEWAVEAQRWTERL
                     KQWQDTVNHYQKQINAYKQELLTKTGIRDVQGLVQSAQSVSKELENIYDQGNSFIDDY
                     IKNPEATLSEQARSLLADYKVTNTCKGLGYTGDLVRGCEASFLSQLAGIEYGNKLESK
                     LREDNQEMADLIDQVKNAQDTKATQDATNAVSLASLKFNKLKFQYEMYRDKQRDLAEY
                     KEKMLQAAFQEKQLGAVNKETPVVDYKAAFEQQSYEMN"
     gene            complement(21888..24641)
                     /locus_tag="IT892_002182"
     CDS             complement(21888..24641)
                     /locus_tag="IT892_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP3135397.1"
                     /translation="MSTVFKGLTRPALIRGLGVPLYPFLGMCVICVLLGVWIHEAMYA
                     LILPGWYAIKRVTKIDERFFDLLYLRMQIKGNPLANKRFNAVHYAGSSYDAVDISKVD
                     NFMKLKDQSSLEELIPYSSHITDNLIVTRNHDLLATWQIDGAYFECVDEADLALLTDQ
                     LNTLIRSFDGKPVTFYTHRIRVRKEVRPVFDSKIPFVNRVMNDYYESLSAAEYFENKL
                     YLTVCYKPFSAEDKVTHFLSRKKGNKNIFEEPINDMNEICGRLSTYLSRFHSRRLGLY
                     EENNIVYSEQLTLFQKLLSGRWQKVRVTNSPFYTYLGGKDLFFGNDAGQITASDHARY
                     FRCIEIKDYFQETDAGIFDALMYLPVEYVQTSSLTPIDKQSAIKALDDQIDKLEMTDD
                     AAKSLLADLKVGLDMVSSGYISFGKSHQTLIVYADSPERLVKDTNIVTTTLEDLGLIV
                     TYSTLSLGAAYFAQLPGNYTLRPRLSSISSLNFAEMESFHNFFTGKEKGNTWGNNLIT
                     LGGSGNDIYNLNYHMTTEHQNYFGKNPTLGHTEILGTSNVGKTVVMMTKAFAAQQFGT
                     PESFPPERKLKKLTTVFFDKDRAAEPGIRSMGGAYFRVKEGEPTGWNPAALPPTKRNI
                     SFMKDLVRLLCTLNSEPLDDYQNRLISDAVERLMQRSNRSYPISKLRPLILEPDDTET
                     RRHGLKARLNAWVQGGEFGWVFDNPDDTFDVDNLDVFGIDGTEFLDNKVLSSAASFYL
                     IYRVTMLADGRRLLIYMDEFWQWINNEAFRDFVYNKLKTARKLDMVLVVATQSPDELI
                     KSPIAAAVREQCATHIYLANPKAKRSEYVDELEVRELYFDKIKAIDPLSRQFLVVKNP
                     QRKGESDDFAAFARLDLGKAAYYLPVLSASKPQLELFDEIWKEGMKPEEWLDTYLERA
                     NLI"
     gene            complement(24666..24956)
                     /locus_tag="IT892_002183"
     CDS             complement(24666..24956)
                     /locus_tag="IT892_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HAP3135398.1"
                     /translation="MLKLNKRYLTLSVFMAALMLCVAEPAFADDVSTKTTGFLQKIID
                     FLTDIRKPAITIIALVIGYIAIFSRQHAAWITPLIIGIIIFIVAPYLPDWLA"
     gene            complement(24940..25584)
                     /locus_tag="IT892_002184"
     CDS             complement(24940..25584)
                     /locus_tag="IT892_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HAP3135399.1"
                     /translation="MLSTTAFAALALQCAASVHPDTAHEVARVESGFNPYAIAEIIPK
                     VERKPGDKGVVSYFPKTKEAALQIVNQIESRNHRYSVGLMQITSTNFANFNTTAEKMF
                     DPCENLKVSEQILVDCYKRGGDILRGLSCYYSGNPETGTKPESDFNNTSYIQRIGFNP
                     PDNKKNWVVPSVKDAIRKENVTQSIKPKEVTVYPQYAMRGTVLDEKETNDVKTQ"
     gene            complement(25630..25866)
                     /locus_tag="IT892_002185"
     CDS             complement(25630..25866)
                     /locus_tag="IT892_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135400.1"
                     /translation="MTATRKKTATRRKPQRNTLYLPSASREELDKIALEIGYRRGRRI
                     SSSGVVQYLIKKYSSQAIEELINEDDEDDDDFDD"
     gene            complement(25817..26326)
                     /locus_tag="IT892_002186"
     CDS             complement(25817..26326)
                     /locus_tag="IT892_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusG"
                     /protein_id="HAP3135401.1"
                     /translation="MEWYVLQFTTTRFAAVFAHLERLNFSYFCPMETERYRRPDKIIS
                     YRERRLPLFPGYLFIQADFEEVHSTTITAIPYVQRFISFGGEPLPVPEDVMAELLYRQ
                     SHTTAQANLLRKSIPHDFAEILLMDNPQQRSMAFIHYITERSLTHKMKRKKNDCYPKK
                     NRNETQAPT"
     gene            complement(26679..27839)
                     /locus_tag="IT892_002187"
     CDS             complement(26679..27839)
                     /locus_tag="IT892_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP3135402.1"
                     /translation="MGVYVDKEFRVKRKSSEAGRKSAFAHKVKNGGKNYQRNVQERIN
                     RKGASKEVVVKISGGAITRQGVRNSIDYMSRESELPVMSESGQVWKGDEIQEAKEHMI
                     DRANDPQNVFDDKGKENKKVTQNIVFSPPVSAKVKPEDLLESVRKTMNKKYPNHRFVL
                     GYHNDKKEHPHVHVVFRIRDNDGKRADIRKKDLREIRTGFCEELKMKGYDVKATHKQQ
                     HGLNQSIKDAHKTAPKRQKGVYEVVDVGYDHYQNDKTKPKQHFIKLKTLNKGVEKTYW
                     GADFGELTTRENVKKGDLVKLKKLGQKEVKIPALDKNGVQHGWKTAHRNEWQLENLGV
                     KGIDRISSSSKELVLNSAEMIKKQQLQMRNFSQIKQSMIQSEQKVKIGIRLG"
     gene            complement(27842..28387)
                     /locus_tag="IT892_002188"
     CDS             complement(27842..28387)
                     /locus_tag="IT892_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="HAP3135403.1"
                     /translation="MKKVQFRIEESQHDDLLDCLKTLYPDEPGLTVAKGMKLLANALL
                     KSKVKNEDVNVSKDNDDFIKTTMYLTGKQRTLIEKAAHRHGWNLSRECRYRIQTTLEN
                     ELDFFDQELLVMNRCRNAIDKIGRNFHYIIVNDNARVLDKDGFYQDAERLSSEIMSLK
                     SEFENYIMLCKGRTVSNKVEV"
     gene            complement(28728..28985)
                     /locus_tag="IT892_002189"
     CDS             complement(28728..28985)
                     /locus_tag="IT892_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001547192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135404.1"
                     /translation="MKKQEFLDFISAEQRRGAVRFSLGFNSKGEIVLHWTNEAGLRVW
                     SILSGNRGKSPSRANRERMSNLRRWLHDARQGMEGDTPEAE"
     gene            complement(29221..29559)
                     /locus_tag="IT892_002190"
     CDS             complement(29221..29559)
                     /locus_tag="IT892_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135405.1"
                     /translation="MNTYVITFQALNTKKEKITCSAFVHSETLFLAVHSFEDKNRGRG
                     YVITSVSELLSEELTAKNSLKKNINFWFNECGLSKSEVINEVINWKNFAYTLKELEEA
                     KNEAIRELRS"
     gene            complement(29653..29895)
                     /locus_tag="IT892_002191"
     CDS             complement(29653..29895)
                     /locus_tag="IT892_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135406.1"
                     /translation="MSFKPTPEEVKQARIKAGFTQQEAAERFGFTLSAWQAKETSGKT
                     SRGLAAGTYELLLLLADEHPDYQLVKREKNQDKVTK"
     gene            complement(29885..30097)
                     /locus_tag="IT892_002192"
     CDS             complement(29885..30097)
                     /locus_tag="IT892_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135407.1"
                     /translation="MSEDATRLFIELEKLMKVRSKEADKKTTKKIVFQKSFYYEEFSN
                     VKDEIDDPILLKFYTDTIVKVQNHEF"
     gene            complement(30163..30714)
                     /locus_tag="IT892_002193"
     CDS             complement(30163..30714)
                     /locus_tag="IT892_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135408.1"
                     /translation="MKEQKNFFERYKPVFEIVCRILGNGWRVNLLDDCQYRIKLTSPD
                     FKNYSIHIRMEKGRLVIIGSVDSRSWRSPYHTCTVSPERNPVEIAADIEKKILSDALD
                     NVDMAREYEQQLQQKREKKLILKGMLSRLVHLESWHGTLTGFKVENGLDGNVSERGDG
                     YEMVIRGLSVDQLIKVAGFIKQL"
     gene            complement(30774..31010)
                     /locus_tag="IT892_002194"
     CDS             complement(30774..31010)
                     /locus_tag="IT892_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135409.1"
                     /translation="MKNKTITEAELINIFESYGAYICPDEIEVTAKECNENGSVLHRG
                     LNAEGWAHLFAKEEAYQQECEAQEAASDDGHFDE"
     gene            complement(31069..31584)
                     /locus_tag="IT892_002195"
     CDS             complement(31069..31584)
                     /locus_tag="IT892_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HAP3135410.1"
                     /translation="MNIQEALNVFGLSGDLTEKDIKAAYKKAALKYHPDRNPLGAELM
                     KAVNAAFDFLMANIDKINQFQSTDENARYNYGEDLEKVLNTLSGLTGIVYEVIGNWVW
                     ISGETKEHKDILKEMGCKWASKKKQWFYRPEEHKSRWNRKEHSIEEIREMYGTAGKRK
                     ASGWTRVEASA"
     gene            complement(32174..32326)
                     /locus_tag="IT892_002196"
                     /pseudo
     CDS             complement(32174..32326)
                     /locus_tag="IT892_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127484.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            32937..33950
                     /locus_tag="IT892_002197"
     CDS             32937..33950
                     /locus_tag="IT892_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP3135411.1"
                     /translation="MRLLLSLDMKILRSSYLKVRGFLIKGCIVVLNYNLCGVMICLHR
                     KGYMRLIVKTVTGLTKVRHRNEVGVTLASLSLSAKRVLFLALCQIDTKEMLDDDILEV
                     DADFFSKATSLDKYASYAALKEGAKVLSSTTLVLNRDDLKNLADELGILSSKNKIPDR
                     LDLNLTEFCAYYDHLATVRIKFTNTAKRYFSKLIGSENRYTTQVLKSVVLLNSVNSTN
                     LYQVIRKYYSQNSSKKSFDISVDDLKEEMGLYTIEEGEKKYKYPKYSFFVRDVINKSI
                     NEIIEKTEINQLSFSVVGKKGRMAHMLRFEFSINEKSSSFSEDDMAFLEEFDKVVPPK
                     KNK"
     gene            33959..34402
                     /locus_tag="IT892_002198"
     CDS             33959..34402
                     /locus_tag="IT892_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135412.1"
                     /translation="MAKIYEFPQGAERSKLKKEIIRERKKRLRETNGNPVIRHAKWFW
                     FYLRLATAGALHLVSVISLAVLGAFSKAIFWIGGMLCVVTWFHLERQFWTPQNFTIPV
                     IVTLWGLSLFATPLMELLNKKMPWYRLLVPDAKHTSTEATNDDQP"
     gene            34590..34943
                     /locus_tag="IT892_002199"
     CDS             34590..34943
                     /locus_tag="IT892_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="HAP3135413.1"
                     /translation="MKYQVKEFINEKYSKAVNILKDNLKEHYHIFYGLRLSEILFPAS
                     EYGSEMFFQEFEAINSVILPLVIFDLIDRKPIMVIGFGEVCGVDSLVDSGIEVVSLDG
                     LSDLLLVEKLTPLFN"
     gene            complement(34964..35248)
                     /locus_tag="IT892_002200"
     CDS             complement(34964..35248)
                     /locus_tag="IT892_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135414.1"
                     /translation="MNKSWLEQQVQNEKLKKVQEEKKDGTIQKGLYRVRIKDKYRWDL
                     WENDFRVVIAYSKDDAELKFTEMTGFNEHYYIESIEKIVLSDIEKILLEN"
     gene            complement(35284..35595)
                     /locus_tag="IT892_002201"
     CDS             complement(35284..35595)
                     /locus_tag="IT892_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135415.1"
                     /translation="MFIFRYIKTLINIYLLYIQPILGMFLIGIGLWGFYAPDEGTCTN
                     LNIELCAVSAIDVLKPAIFVFLGIITVAGWYFTELQPKLRGEGKYMKVKTGVKPEDFV
                     K"
     gene            complement(35801..36085)
                     /locus_tag="IT892_002202"
     CDS             complement(35801..36085)
                     /locus_tag="IT892_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HAP3135416.1"
                     /translation="MALKLNRPNIDESQQPATNAETARFISGATRAPVAGKPKLMNFR
                     LPAYFEEILEAEAQRTGQSKTTVLKAALAAFDNLDENLKNHWLLESAKLG"
     gene            complement(36185..36847)
                     /locus_tag="IT892_002203"
     CDS             complement(36185..36847)
                     /locus_tag="IT892_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-arginine deiminase"
                     /protein_id="HAP3135417.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHD
                     LLSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVS
                     DIVVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDL
                     DKLLRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIG
                     IL"
     gene            37228..37890
                     /locus_tag="IT892_002204"
     CDS             37228..37890
                     /locus_tag="IT892_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP3135418.1"
                     /translation="MTQTVPKGFVRAYLRASTTEQDATRALDTINTFAIERGLSICNY
                     YIENESGSKLERPELFRLLKDCQQNDILLVEDVDRLSRLVGEDWNTLKKMIRQKDIRV
                     VAVNVPTTWLASGHNDFDSRMFSAINDMLLDMLAAVARRDYEQRRERQQQGIARAKRE
                     GKYKGRQVNQSRYDAINRLIASGSSWSQIQKVLGCSRATISKAVKQQTVNKMNHEPEG
                     RE"
BASE COUNT         9783 a         9003 c         8087 g        11074 t
ORIGIN      
        1 tagataatgg ggttctaggg attttccgtc caaaaacgac aaagtgctct ggaggccgcg
       61 ccgtccgtgg cctccagagg ggtattactt ttcgctgacg ggtaaatatc cctcgattga
      121 gcgcataagc tcctccagat ctggcaattt ttcgctcaat tcgaagtggt aagtcccctt
      181 gaggttaatg ttgtgccagg ccacagggga tgcctgtttg acgatatcta ttctcttggt
      241 atctccttgg tattcgaagc tggtcaacag ctggctgagt atcctggagt tgaagtaaac
      301 gatggcattg gtgaccaggc gagcgcactc attccatagc tggatttctt cgtctgaact
      361 gccccggaac tgatccccat tgacgctgct cacggcccga cgcagttggt gataggcctc
      421 tccccggttc agcgcgcgct gaacatagtt tcttaaactg gcatcatcga tgtagcacag
      481 tagataattc gctttcacca ggcgattgta ttccgtcagg gcttccagca gcgggtgatt
      541 gcgcttgtac tccgagagct ttctcaccaa ggtggcttgc gttgttttcc gctgcttaag
      601 tgatactgca atccgttgga tggtatccca gtgctgcgca atacgatggg tattgattgg
      661 cttttttaag cacagctgaa ttcggtgttc tttgtcttcc ttgacatcaa acatgtcatt
      721 gatcactttg ccaacctggg catagcgtgg ggcaaactgg tatccgaaca gatccagtaa
      781 cgcgaagttc acatggttca ccccatgggt atcggttgag agcacatccg gaatgatgtc
      841 tgacgtattg ctcatcaaca aatcaaagat gtagtgcgat tcatgttcgt tggcgccgat
      901 cactctggcg ttgatcgcag cgtgattggc gatcaaggtc atggcagaaa cacctttttg
      961 agtgccaaag tacttcgacg aataacgggt tttgaaggtc tcgcgccggg cttcgaactt
     1021 ttgaccatcg gcactggcgt ggatcacatc ttcctggatg ttgtagtacc ggaagatggg
     1081 tagcttggct gtcgcgttat tgatgttgtc gttagcagca ttcaatgttt ccaggcgaag
     1141 atagttcgcc tggatagtgc tgagctgatc ataggtacga tcagagatct gtgccatgcc
     1201 gtaaatgcct tgattggttg cattgccgac cagaattgcc aacaggtcat attcatggga
     1261 acggcttctg gattgggaac ccagcacatg agcgaagcag tcaatgaaac cggtgtcacg
     1321 atcaaccatg cgcagtacat ccgcaatccc cgttgtggga atttgctgga agaagggatt
     1381 gttgaccaga tgatgtttgc tggccgaagg caggcgccag aagcgtttac cctgcggatt
     1441 acgcaagatg atattccggt tgtcttcctg ttcaagatat tcgccgactt cgtacaaacg
     1501 ggtatccaat tccatggcca tctgtttgat cagcttttca ggctcctccg ctaattttgt
     1561 aaaatggctc tgttgaagca gcgtatattt gttttttcgc caatgttccc cgtcgatcag
     1621 gtcggcgtcg agtgcccggt atttagtgat atcaggcagc gtcagctggc cattcaggcg
     1681 atcaggaatc tgttgataga ggaaccactc ataacgatcg atcaggatat tcccttcacc
     1741 atccagcagg aattcacgtg attttttgga aaggagtctg gtgtcggcag tttgcaactg
     1801 agcgtcctgg ccgttgagtt cgttttgtgt tttcgccaag gcggccgcta agtgctgggt
     1861 gccgtcgcag ccttcgaagc gcagacatag gaacaactct cgcagcaaac ctttccgcag
     1921 actttctttc tcgtcgcagt actgccacat ggcttcatcg accgatcgtc gctgctcgtt
     1981 caggaagaga catacagatt ccagatccct tttggtcagc aggctcagtg cttgctgtct
     2041 tactgttgca aacggtagtt gcagatcaat gctgtcatca atgaacaggt gcagtacttc
     2101 agctgccttg ctgacatttt tagctgcttt ttgccaatcc ttaaacaccg cttcctgcgc
     2161 ataatccttt gccttctgtt tggtctgtct gacatgatgc acaaagccat cggcaatacg
     2221 ttccagcgct tgctgccatc gcgtttgaag atagcacaat aaatacagcc attggctgcc
     2281 tacggtttga cgtttcagtt tggcaccgta gtagtcgact ttctctgcca ggtgttgcag
     2341 atttttctgc gacagtgata gcgtgctcaa cagcagatcc acttccggca tccaatgctg
     2401 gatatggcga tagacaatca gttctttctc caactcggtt ccggtgaagt tacgagccga
     2461 ttgtcgcaac tgtcggaacg gcagtggacc tgtgccgttc acgagctccg ccagtgcttg
     2521 cttaagaccg cgtgacattg cacgctcaag gtgcgcggcc atgtgttcct gttcgtctcc
     2581 caccacctga ctgatgatct tttgcagcgt gctgtaggca gggattgcga tcttctgccc
     2641 cgaacaatat tcattggccg catcgaagag gtgcctaggc gctgtccagg ctctggcttg
     2701 ctgggataag taatctctca acgccgctcc atggtctttg acattccagc gctggtagtt
     2761 gcagagctgg aaaacacgtt ggtaaatccg ttcgttctct tttggcgtga gattaaaggg
     2821 tctacagcct gggcctggta gaacggtttg ataaacgtat ttgaggtcct gcttgatctg
     2881 atgaaagccg ggattcagca ccaccggctt ggctttgaaa tagcccagca gtaccaccag
     2941 catgtaacgc tggccccgat gacggaggct tttagcgatc gccagttcct tatcgttcag
     3001 cgagaaaaag aagcgttggt cggcggaggt gaaagcgggg ggtccatata actcatcttg
     3061 ttctgcctcg gacaagattt ggacacgttc ttcgaatgcc atggatttag cccaaaaaga
     3121 ctaaatctta ctcaaacaga gcccaaatag ggatctcgaa aaaagtaata cccctctgga
     3181 ggccacagac ggcggggcct ccagagcact ttgtcgtttt tggacggaaa atccctagaa
     3241 cccctcagtg ggacgaaatg atccggaccg ctggctccct gaagctgggc aaagtacagg
     3301 tttcagtgct ggtccgttca ttgctgaaaa gtgaacgtcc ttccggactg actcaggcaa
     3361 tcattgaagt ggggcgcatc aacaaaacgc tgtatctgct taattatatt gatgatgaag
     3421 attaccgccg gcgcattctg acccagctta atcggggaga aagtcgccat gccgttgcca
     3481 gagccatctg tcacggtcaa aaaggtgaga taagaaaacg atataccgac ggtcaggaag
     3541 atcaactggg cacactgggg ctggtcacta acgccgtcgt gttatggaac actatttata
     3601 tgcaggcagc cctggatcat ctccgggcgc agggtgaaac actgaatgat gaagatatcg
     3661 cacgcctctc cccgctttgc cacggacata tcaatatgct cggccattat tccttcacgc
     3721 tggcagaact ggtgaccaaa ggacatctga gaccattaaa agaggcgtca gaggcagaaa
     3781 acgttgctta acgtgagttt tcgttccact gagcgtcaga cccctgttac cgatgcaaga
     3841 acaggggagt ttcatgaaat gcctgtttag gagtgattaa aggtaacttg tgcgcagaag
     3901 gtcaggtgtg tggtggttag tacagactag tgaatgttgt aactaaacta tatttttatt
     3961 aaaggccgga ggtggtgttc ctccggcctt aattacgttt ccgtgttcat tagtcgatga
     4021 actggcggat cagttccaga atggcaatca gcgcgtttgc aagcgccgct accgccctca
     4081 gaacgatgat taacaggtta atcatccgtt ttctccataa atggagtaaa gacaccgtgg
     4141 cttgctctta cactgcctgt caccacggct tctcttcgtc ttgtcagttg tagagagtct
     4201 cactcctgcc agagcacaga taaccagcac cacctgtatt acctgtcagg actttgaacc
     4261 tgttcatgcc gcatttagcg gaatgcaggg agagactcac cacagagcta accctctgat
     4321 tatacgttta tctaacgttc aggcaaaccg ttaacgcaca gtcactgccc gtcatattgc
     4381 ataatcaggc ttcacggatt atcatactat tgtcagttgt agagagtttc ccttccgggc
     4441 tgagttacca gctcgcaccg gaaccgtaaa aaagccgacc tcaccagtcg gtttttttac
     4501 gtctgcggtt tcccgcttcg tttaaatcta ttttaaatga ataaattgtt ctgcggcaaa
     4561 cccaacaaca taaggacgtt agggttgatg gttgccgaaa tcgcggtgcg ttacgtgaat
     4621 tctgaggttt tgcgaggggg attgggcgcg agaatttacg agagagcgcc ggaacaatgc
     4681 cgggatcaca aaccatcacc cgtgaaagaa atcttccggc attgcccggt caggtagtat
     4741 gacattcatt gtcaacggcc atcaatttat aagctgcttt gcacttcata aaagatcacc
     4801 accagggctg ctaaaacagt accgatagcc agcacgttaa aaagtacgtc cttcatcttt
     4861 acgaacgaca tactgatttg cgtcctttcc cttttgtcag ccttctctat catccagcgt
     4921 tggtatgaat cactgttact ttttctgtcc atgttccccc caattcatca atgagcacca
     4981 ggcggccacc aggcttcttg ccaacaaagt aacggcctcg cggcagacgt tcgccagtct
     5041 tcagccgttc gatccagtcc tgaaatgcag ggcgcggttt atagctgtag cggccaaaat
     5101 cagctaaaga ctgcgtgacc atgactgttt ggcagccatg ctttctcata tcacgaaacg
     5161 tattttccag tgcagccagt gtattcattt gcacgttctc tctgcttttc ccatgaagat
     5221 attaacgaca ctcaaaacta acaccgttgg catgatcacg gcagcatagc cgacagcaac
     5281 ggcctgatat atggtcaatg agtagtcggg ctgtttatac aatacgactg aaaaaatgct
     5341 ccccaaacaa gcaagcagag ttaaaaacaa gtaatcgaca aatctgtttt tatagataac
     5401 ccatgcaacg atgcagggat atgacaccag gcacaggata atcgcatttg tggtatgcac
     5461 gtttcgctcc ttgttattta agggttgtca gccagatcaa acagattgtt caggctggaa
     5521 cggaattgtt ttaccgatga taccagctcc tgactccgcg ctttttcctg cgccagttca
     5581 cgccgtagct gcgccatctc gtctctgtta cgctgaagct caaggatagc cgtcataaag
     5641 gttttgctgg ctgatgcctg tccggtcgct tcctgcgcct ttttaatggc ctgatcttcg
     5701 tcgtcattcg ttctgattgt gtaatgcccc atgatacccc tcttttgctg tcatttttgc
     5761 gctgccggcg cgaacccggg aagaaacttt gctggcaaaa aacactggcc aacagatgtg
     5821 accgggaaaa tttgctggca attaattttc gatgaaagcc agctcgcaat cgccgcattc
     5881 aatattcagt ccggctttgc cccacacggc agcgccacac ccgcgacact gatatttaac
     5941 tttatttcgt tttggcttgt cctcaaatgc tgcaactgac aaatcattgt cattgctccc
     6001 ggccatatca tctgaatggc tcccgttctg cggtgacact gacggcagca gagccataga
     6061 aagcaccgct tctatatcaa tcccggcctc agcattttga tgcgccagag caagcgtttc
     6121 gcgccattgc tctattacgg cggtcatatc tttttgttgt tcgacctgga cagggaagcg
     6181 atcaaaccag ctcaaagcaa attgcccctg gaacagttcc agtgtgacgc gctggaagcg
     6241 gccaccaggg atcggatagt cattaatctt ctggccgact ttcgcaccac caggtctccc
     6301 ggtggaggag ggcataagtc cgatactttc catttttgcc gcccactgcg cattgtggta
     6361 cgtcttacgc gacgggttgc cgtagtggta ctgccacata tggcactgct catgaaccag
     6421 cgtttgcatg acttcaataa gcgggtacac cgggaagtat tcaggattga gggcgatttc
     6481 atcaatcatc ctgccgctgc cgtcagcagc aacaaagcgc ctgtaactga aatagcccat
     6541 tgtgttcttg ccgcgctgga acgtaatcag acagtcaggg agttcgccgt caaaaaggcg
     6601 ctggttatag aaatcaaacg cctgttgtag ctcgctgtaa gcgcgttccg tggctcttgt
     6661 catgctgaag ttcgcttagc ggcgttccga tattcctgta actctgcaac aatagcaggg
     6721 aacacatcag cgcaacgctg tgccagctta accgcctttg aacaaacgcc cataccatgt
     6781 gctcttttga gcgcctccaa caaatctacc agttcctcgt cagtgatttt ttcagtcatc
     6841 tattaagctt ctccattatc tgtatcgtac gatacagata atataaacca cacctttgat
     6901 agcggcaatc ttttttgctg gcaatttcac gcccagggcg ggcatcgagc gggtaatatt
     6961 gctggcaaaa atcaacggcc aaaccggctg caggaaactg gtttgctggc aagcgtgatt
     7021 tactgctggg cttgacacct tgccattgta tgacgcttgt tttagtgtca aatgaacaac
     7081 cagcgcgaga agaatatagg aagcaaaagc aatggatatc aaacctaact cagtgatcca
     7141 cctggagcca ggcgaaacat tacccggcta taccaatctg aaacccgtac ctgataagta
     7201 tttcgatgag ttaaaggcac tcataaataa actcaatact caatccggta atatttacct
     7261 caagttaaaa cagatgtacg cctttttgga tcgttttaac aaagaatttg tgagcacgtt
     7321 tacctcctgt caaaaggggt gctcttcgtg ctgtaaaatg gatgttcatt taaccgcgct
     7381 tgaggcaaca catattgcac aagcaagtaa acttactgcc agagacaacc cgcttacgac
     7441 cgggcatgag tcaaaatgtc cgtttttgtc tgagaaggga acatgctcaa tctacaatta
     7501 ccgcccgctg ttatgcagga catatcatgt actcactccg ccggagatgt gtaatgacct
     7561 ggatgcacaa gtcatgcagt atggttctca aagcgcgaac atgggaaatc acatctacaa
     7621 aacaatagca gagtggatct attttcagac gtatcactgc actggtaagt tagaaaccaa
     7681 agatatcaga gactacttcc cttatccccg cgaagatatc caaagatttc ttcaccataa
     7741 ccccccgcgc cctttttgct aaaaaaaagc ctctgacgca gtgtcagagg cttgttagat
     7801 tactgttcgt caccagcagt gctggaagca tcttttttga tgagaaactc atcaagagaa
     7861 cggccagctt ttaacgcttc gtcgattggt tttggtgtcc ggccacgacc agaccagtat
     7921 ttcgtttcgc cgttttcatc aaactgatat ttaggcggcg cttttggcaa cgtctttttg
     7981 cgtgtttttt gcgcatcttc ggacaggcca agcagttctt ccggtgaaaa accttctccg
     8041 gcaatcaact ggagcagttc ctggcgcttt ctttcgcgct ctgcgcgttc tgctgcctca
     8101 cgctctgctt cttcacgacg ttcttcgatc acggcgttaa gcttttcctg catttccagc
     8161 agttgttcaa agctggtttc tcgcgcaaaa acacgaacag agcgaatatt caggagtagc
     8221 ttttttgttg cgtcaaacgt ttcattttca ctcatcgagt taatccttat tttttactga
     8281 actgaaaccc aagtttaccc gtagttttat cctgcaaaac aattgcagcg tcaaactttt
     8341 tcccggtttt attactggta aagcctttaa tctctccggt tttacctttt ttgattaatg
     8401 tctcaacctg attttgtgtc agtttttttc ctgacacttc agaccagatt ttaaactcgc
     8461 acccggaaca gaaaaagcct ttaggccgga taataatttc tttactgcat gaagggcagg
     8521 gggcttcgag ccgggacatg gaaccttctg atctggattt tgcttccata tccggtttgc
     8581 cgtctttgtc cgggaatgtt gtcttgcatt cagggtagca ggagcatccc cagaaaaagc
     8641 cattttgccc cttacgctta cgcaggaaac cgttgttaca aaccgggcag ggcgtggcat
     8701 ttgaagaaat cgaaattccg ttcctgtcca gctcgtcgat taacccctgg acgtactcat
     8761 cattttcctt aataaactcc tcaactgtca gctctccggc tttgatctga gactgctttt
     8821 cagcccacag agcggagata tccggtttag tgatttcagg aggcagtgca gcgcaaaact
     8881 cctggccttg ttttgtggtt ttccatacca gctccgaata ccccttttct ttttcgatgg
     8941 agataagccc ggtatttgcc gccagtttct caagaatacc cgcgcgggtg gcttccgttc
     9001 cgatactgcc acgatcactg ctgccctcgt ctttcgcttc cagcgccttt ctgagagccg
     9061 gatcatcaat gaattttgcc gcactcgtca tggcggccag taacgttgac tctgtgaaat
     9121 agcgaggtgg tgtagtcttt ttcttgtcca cgtctgccga ttcacacagg ccgctgtcat
     9181 taaatttcag caatgaaagg tcaaaaccgt ccgttccggc atcttcggtt tcgtcctcgt
     9241 catcactatc cttacccagc gcttcccagc ccttttgtac cagaacgctc tgtgtggccg
     9301 taaaggtatc ccccttaata tcaaagtgga ttttcgtctt gttgcggatc gcatccgggt
     9361 agaacagccc gataaagtag acggacacca ggttataaac gttccgctct ttttcattaa
     9421 gctgaatacc ggctccgctt tttgtcgtcg ggatgatggc gtggtgcgcc tcaatcttac
     9481 tggcattaaa ggctttgtgt ttctggcctt tatccatatc tacgatcgca gacgccagtt
     9541 cgggtacggt ggccgctata gcagtggcaa tatctccggc ctggtaataa tgctcatctg
     9601 aaagatagcg attgtcagaa cgtggatagg tcagaagctt gtgagtttca tacagcccct
     9661 gcatcacatc gagcgtatct tttgcagaat aaccaaatcg ctttgcgcag agctgctgaa
     9721 gcgtggaaag gttaagcgga agcggaggct tgctattttc cggctttgtc gtcgcgatag
     9781 taacaatagc atccttaccc gtaacacgtc cggcaatatg cgcggcctga gcttcggaga
     9841 tcaggcgttt tttctcgtct atctgatcgt cgtctgttgt ctgatatttc gccttaatct
     9901 gatgcccgtt catcgacaga ctggcgaata catcgtaata aaagctttct gtgtgattct
     9961 ggttcgccag cgtgcgcatg ttcaccagac caagaacggc actttgtacc cggccaacgt
    10021 tcagaacgcc gtcatagccc ttctcacggc cttttaatgt acatccccgc gtcatgttat
    10081 agccaaaacc ctgatcgcac agggaacgcg ccagggcgct taacgtcata ccgcgaaatt
    10141 tatcgttagg ttgtaaattc gacagtgatt tttgcactgg cgcaaggttg aggtcggcaa
    10201 caagcagtcg ctggacgggt ttcttgtttc cggcataacc cagaatctca tcaaccagca
    10261 aacatccttc atcatcgggg tcgcctgaat gaacgatgct gtcggcttta tcgataagag
    10321 acaaaataat gcgggtctgt gcttctgatt caggcttgat tttatatttt ggcggataaa
    10381 ccgctttaat gggtaaatca ctataacgcc agttggaata tttgtcgtca taatcctgtg
    10441 ggtcgtaaag ctccagcata tgaccataac accaggtaac gacatcagaa ccgtgttcaa
    10501 aatagccgtt tttcttttct gtattgggat ttccgcccag tccttcaaaa atagcctttg
    10561 ctaaagacgg tttttctgca ataaaaagtc tcattaatca atcctcaagg taacttgaat
    10621 agtcaggctg cgcaccattc tttttaaaga tttcttccct ttcctctatg tcttcttctg
    10681 cctcctgcac actaaggtca agggttcctt tcaaaaaggc acgcgcattc ttgattacat
    10741 ctactgttaa ttcgtttttt gttccgcgaa tcatgccaat agcaatattt attatctcct
    10801 ttatttcagc aggagtcgtt ctgtccagca ccgcgccaag ttctttaagg tcaatattta
    10861 tatcgtctgg taagtacatt ttggcacaag cggcagcggc tttagtccga aaagcaccta
    10921 cagatatgat tctgtcaatt ctgccagggc gttttctgat gcgcggatca atccggttag
    10981 gatagttcgt tgaaaaaata acatatgtcc cggcaagatt tcgcggtgta tcagccccat
    11041 caagaaaact taacgttccg gcatcagccc gataaagttc atcaacctct tcagctatta
    11101 tgataacggg tattttcttt tgagctgcgg catagcaaac atctttaaag taatcatcag
    11161 cataaacaaa tacatattta tcctgatatt ttgcccccaa agcttttgcg atagtcgttt
    11221 tccctgtgcc cggaggacca gtaaaaagca cttttcgcat tcctgactga ccataacggg
    11281 tgtagaaatc aatatccgaa aagaactgat taaagtcatt ctccagctca ttaaactttg
    11341 gatgaacaga aaaacgtaaa gcgttttcta tttcttcctt ccttgcctta ccgtgataat
    11401 aaacgccgtc gtaacacccg attttccaga tacctttacg gggtaaagag cggtttaatt
    11461 tagcgcgtcc agcttcgcaa agattatgaa gcatcgacat acttttggtt gtgccaactg
    11521 cgtactccat tctgacttta gagttaagaa tgaagcgaat aatatgaacc acttcatttt
    11581 gaccaagatg aatccggtat gctcccgaac catctttaaa cataagcttt ttaatcctcc
    11641 cggctttagc cataacaggg ctacttcccg tatgaacgac ggttgaagca acgggttcga
    11701 tatcaagatt cgaataaatt ttacgattct ttctgtttat aaaaatctct gccactttag
    11761 gatagtaatc acaatccttt acgacagtac caaaattatc ttcaccgtaa tattctttat
    11821 ggagccgtaa agcctgctct accagagtta atttacccat atgcgcacca tgtatattaa
    11881 aaaccgtgac gttgcctgaa gattttcttc aggcagagga ggggttggac aagcgaagcg
    11941 cgtcagtttt gtttatgacg ccactcccac ggaggaacgg gattactgtc agcccacagg
    12001 ccgcgcttct gtgtctgagc ttcccgttgc agagccggta atgagttatc ggtgttgtac
    12061 ctgtcataaa cccatgcagc cccttttagc acttgctggc ggttagcctc agtgccgttc
    12121 gctgtcacca ctcgtcccag gactcgcccg tagcgatctg tttgcgtata agagacggta
    12181 actgattgcc ctgccagcag ggctttaagt tgattggttg accagcgacc aaagggttgt
    12241 tttttttccg gtgcatcgat atttatcaat cggactcgaa tcggaacttc atacacaaca
    12301 attttcgcgg gtagtgtttt aacttcgatg gtatctccat cgagaacgcg aataactttc
    12361 ccctgaatct gagcagcaca caatgtagct ggcaacaggg caacagcaaa ggaaagaaca
    12421 ttaaaaaaat gtctcattgc tttcttccct cccatattgc tgagagtctt ttaaaaatgg
    12481 ataaaacgac gactaaagcc actgcgataa cagccaacga aggaagtaca tagctgtata
    12541 actcaaccat gaaattaata aactcaatga gcgattgcgg ctttaaggaa gcatcccaca
    12601 aaacgataac aaaacgataa agcccataga caattgccgg aaaccagacc ataaacaaca
    12661 aaatttcagt aaaaacagaa gcgaccgatt tgacactatc gataatttca attccggcaa
    12721 ttctcacact tcttgcatca ggtacgttaa taattttcat cctcccaccc ctgtaaaaaa
    12781 tgttcgcaag ttccagtctc aaacctgaaa cttgcgtatt cacatcagaa ttaaatcaaa
    12841 cagaattaaa agtttttcaa tcggccaaag cttgaaataa ttttacttac tgtacctgca
    12901 tcagccgcag gacattcatt tagttttttc tttctggcat ctgccgtgtg atcgggtaaa
    12961 aaaccatgtt tattcttttt cctgattgac ataaaacttt tatacatcgg gtcacattct
    13021 gccggactac ttccgtcaag ttttccggca aggcataaca ccattgcaca tggatcgttc
    13081 gggtcggcct tttcctcagc atgagcagtt ccggcagcga acgcacaaag cagcactgcc
    13141 gtggttacgg tctttttcat atacacctca tggataacgg gcaactaacg ccctgcggtt
    13201 gttcaacccc ggctcaataa aattacaaga attttattaa tccggcgtta tcgtgataaa
    13261 taaacactgg tagtccggca agaaaaacag ttcattttat aacgatactg tatgacaccg
    13321 tttgcaccgt tcgccctcaa ccagttttta gctgtgaaaa agtctgttcc gttactggtt
    13381 tcaacaatca ctgaatcaga atgtgcaaca gaataaaaaa cagcatcatc gtaaaggcgg
    13441 ttttcaggcc tgaaattatg gataacctta acccacgatg aattaacctt gtctgattta
    13501 ataactgagt atgtcggttg ccagtccatt aattgtgtat tcaccgtttc aggattctgt
    13561 tcccagtcaa cctgtggtgg ttcaggcgga gaggaacagg cagagagaaa aaggacactg
    13621 accattaaca tttttttcat agtaaaacct ctgactccag ctcaccgacg gagagcattt
    13681 tttctttaga aggatattta agccctttaa cacccaatac ttttttagtc ttattcagag
    13741 aggcggttaa ctcggtaagt ttggggctta ccatcatcag cctgtccata aaatacgggt
    13801 cgaggaagta gagggctttc tcagctttaa ccgggttttc acctttaaga atgataaatt
    13861 cttctttaaa atccagcgtt cccagctcct gcgggagcac aagggcgcgc tgcgcctcac
    13921 tttctgaact gcttttcgac gttgagcgtc cgcttgtctt gcttgaacct gtcgatttgg
    13981 tggtgatata gcccagcttt tccgaaatct ttttagcgtc atcttcttca ctgacagcgt
    14041 agataatccg gcagggatgc gcactcatca gcgttttggc accttcaaca ccatagattt
    14101 cattaagctg actgatattc tggtaaatcg tcagaagttt gagtttaaac ccggcaatat
    14161 aacccgaacc ttttttaatg attggcatgt aaccaataga cggaaactca tccaggaaca
    14221 tcagacagtc atgtttcagt gtcgggtcaa agtcagggtt ttctcgtaac gtgacttcca
    14281 caacgaagtt aaagaacagg ttgaggaagt cataggccag ggacatatct tcagcattaa
    14341 cgccaacata aacagtgata tcttcccggc gcaactggcg aaggtcgaaa tcattgccgt
    14401 ctgtacattt gcgaacagtc ggaagataaa acagactcat tttcttacga aacgaaccat
    14461 caatactcga acgttgttcg tcttcggttt cgtgatactc cctgattttg gtcagggcat
    14521 cgcgcagatg atacagcgcg ttttcatcaa gtccttttgt tccctccagg tcttctcgct
    14581 tactgagtat cagctcccgg tcgatgttgc tgtacaaatc gactacagaa ccaattgaga
    14641 aaacaggttt aagcccgaac tcaccaagcc aggaggggtc gtagttaata aagaaatgaa
    14701 gcaattttgc cagccccgtc cagtactgcc ccgcgaggtt attaaagtgt gcttccgctc
    14761 cggtcagacc gtaagacggg aacaggatct caatcagctt cagcaggtct ttagccccgc
    14821 tctcttcttt taaatcaata tagaaaagcg ggttaaactg atgcgtttta ctgttgaaag
    14881 ggtcaagaag atagacctta ttacccagca gtttttcacg taccttactg gtgattttcc
    14941 acagttcctg ttttggatct aatgcaatca gggaatgttt cctgaccagc aggtttggaa
    15001 tacctattgc agccccttta cctgcgcggg ttcctgcgcc aagtgataca aaatctggtg
    15061 cggtatacca caggtattta cctttatatg cacctacaag aatatcagta tcgttttctt
    15121 tctcccattt cagaagtttc gattttctta aatcattatc actggcaaac ttcgcgtcac
    15181 cataaagagc aacatccgtt ttattcagtt gccagataat aaaaacaggc acaatgagag
    15241 acgaaaccat acctgataaa agagagggga ttgcggttaa cctgatatct gtccgtatat
    15301 tactctctgt tattatccgc cacagcagca tggaatcaaa attcttccat atataaagcg
    15361 gcgtttttcc gttcaggaag taaacagcaa ctgagccagt ataatacgtc acaagacaca
    15421 taaccagacc gataaaagcc cactggcctt tatcgggtag tttcagagac ataatcactc
    15481 cttcagcttt tcaaagtatt cctgaaaatg aatatcacga tagtaaatac ccgatgcaaa
    15541 tcggttatct tcctcatcga tgtacttaat actcataatc acatcgacgt tgcttaacac
    15601 cctccgcaat ataatgttat aaggcaaatt ctgacattca gggttcatat agcaccgttg
    15661 aaccagtcca agcacagcat cttcaggggt gctctcatgg acggttgtaa ggttccctgc
    15721 atggccggaa cttgagcctt tgagaaaatc ccaggcttcc gcgccgcgaa cctcagtcat
    15781 gaggattctg tccgggttca tacgaaaacc agaacgtaaa agagaagcgg aactgacagt
    15841 gctactttcc ccttctgacg ggtaatacaa tttcacatga tttttgtgga acctgaactt
    15901 tgcttcatct gtatcttcaa ttgaaataca tcgtaaatga tggggtatgt actgaagaca
    15961 ggcatttgca aaggtggttt tacccgcccc cgttccggca caaaatacca tcgttttacc
    16021 cttaaccagg cattcaggga caaattgttc aaaacaatta tctttaaaca ttgaagataa
    16081 ttcatcttct ttatccctga atttcccccc ttgatttagc cttgagtaaa acccttgttt
    16141 aacaaaggta tcatggtcga taaacacact ggacggctta cggattgtaa tagacaccgt
    16201 ttcccgttcc gttgccgggg gaataactat ttgtacacgc tcccctccgg ggagcgtaac
    16261 agaacgtaag ggatattctg gcgtaaccga cccaccatca tgataatcag aaattgcccc
    16321 tgcaaatgac atacaatctt taaaatccat ttttaattca tgctgctgcc atttcccact
    16381 cactttaaca aacagttcat caggccgatt taccgcgatt tcagttaaac catcgacttc
    16441 attaagccag tggtggaagt attcatctat tatttcataa acaatatgtc tgttctctgc
    16501 atccttcata attcaccttt tcctttaaga tcttcaataa aacgcatgac ttcttcgtaa
    16561 ttaaatcgat gcgttttgat ttgtttcagt ggtttgggga aaggaacgcc atttattggt
    16621 atgcccttac gaatatgatg gtatatttcg ctttccctta ttcctaacag cattgaaaac
    16681 tctttgatat ccagcgttat caaattacct ccgggtaccc accattttta atttgtagat
    16741 gctggagaaa tccaaatcct gaccaacgat cagagtaatg atttccccct ggtttttata
    16801 aagcgttgga gggatattta cgctgtttgc aaacgcttcg cgtgctatat cagcaaaagc
    16861 ctggcgactg ttagctgtat agtcggtctg attgtcttta ttacttttag ccgctccact
    16921 tgcggcctgt gccacatcgg ggatcatgcc aaccatcatc gcgcccataa agcgatctgc
    16981 aaaatgtgtg tcaatccagc ctgaagcccc ggcctcaccc agcgctcccg ccgcctgtgt
    17041 atcaatcagc ggaatatcaa tgaaaggttc cttacgtgtt ctaagcttcg tagcagcgat
    17101 aaacacggct ccctgaccat gattgaacgt gcccgtttta tacatcagat atgcggctgt
    17161 tcccttttca attagcttta cattcctgtt tgcactgtat acgtcctcat taatcgtaca
    17221 gaccagcttg ccagccagat cagaaataaa tcgtctgtcc agcgagcact taatcgcggt
    17281 attttcagga atgaaaaggt tagggtcata aggaacgcgc gtaattttag aaagctgcgc
    17341 gggttgccct gcattaacag gctgaacctc tgcctgtttg tcactgccgt ccccctcgtt
    17401 cctggtattg ctggccgttg atgagctacc accggaattt gaggaagcag agctgctccc
    17461 cccataggcc acatccagcg cacgactgaa gttttgttgt actttttccg gtggcgtttc
    17521 cgctttgccg ctgctttcct tccgttcttc cgtcttagcc ggttcttccc tggtgttgaa
    17581 tggatcaaca tcatcgctga gtcctgtcgc gcgttttact gaaccagtag ataccgcatt
    17641 actggcaggc ttatcatcac cgctggacat tgcacgaata atcgacggga tatagtagac
    17701 agacaccccg gcggccagca gaaggaaagc ggccacaata atcaccagcc ccttacgcga
    17761 ttttttaagc ttctcgatac ccaggcgttt tactgattta ccgtcatctt catctccctt
    17821 atccgtttta tcgttttgct caatttcttt ctgatgccgt tcccgtagtg cctgttcaat
    17881 ttctacagcg gtcgggattt tattttcctg ttcgctcact ggatcacctc tttctcaacg
    17941 ttcggggaaa cggtatctcc tgccggaaga cggactttgc caaagccccg gttttcaacc
    18001 ccaacaacct gatttcccat acgcaaaaca aagcgctggt ctacaggaac accaacaacg
    18061 gtgaaactac cgctgttttt gactaccggg ttagtcagcg tttcctgttc gccgctcata
    18121 acaaagacgc tggggatttt cttcaggggg ctgaagccaa accaggtata gcggccatcg
    18181 tcatacgcat aatccgggct gattgactgg ctgccgtcag ctacccgctt ccagtaatcc
    18241 cagttcttgg gcgacttcgc attttcaaga gaacggttga ttgcctgctc ctcctgccgc
    18301 ttgttaagag cctcaatccg tttcttctcg atttcggctt gctccttccg gcgttcctgc
    18361 gggtactggt aattaacaac aaacgcgatc ttatccggct gccggaacgt tcgggcgttc
    18421 agctccatgc tgtaattacg ttttgttgtg cgaacaaaca ggtttgttcg ccagcgttcc
    18481 aggtcgtttt caggatcaag ggctacactg accacctctg aagactggtt gccattgtca
    18541 tcggtactgt tcttctgtac ggtctgtttg acgggcttca cttcgagata caccaggtta
    18601 tcttctttgt tcacttccca gccctgggga aagccggttc tggcactgat gaccgtttca
    18661 tcctcgtcaa ataccagtgt ggttgtatag ccaaccgcac tgtttatgac tgtcgtgttt
    18721 tgcgggttat aactgacaat ctgattacgg ggatcaaaac ggctggctgc tggcgtaacg
    18781 gctgcatggc agacgtgcga caccaacaga agcgccacaa ttagcgctcc tttattcatt
    18841 ttcatagttt tcaccctttc acttctttat cgcgtacata gctcgttaca acgaatttaa
    18901 gcgggttatt gtttcggtca cccgatgcca tttcgacctg tggttcaata cggtaggtca
    18961 accggacgtt ccagtattca taatcatcct ggcctgtcgc gacatttcga atggttaatt
    19021 taaaccggat atatgctccc atatccttat catcgcgccg ggatgacgga ctgataatca
    19081 cggacggatt atcctgaaca gatgcggttt tttccgcttt attataaata acctttggtg
    19141 actggttgcc gttgattaaa gcgttgtaat ccgtcgccac attctcagcg ctgtataaca
    19201 gaacataatc ataatcatgc tggagactga aatagttata cccttcacga cgcttcacat
    19261 actgagtaat gaagtatttc gccagcgctt cattttcaga gaggttttct tttttaacag
    19321 aagtcagtct ttcagcaacg ccagtgacac cattaataag ataagcttcg acaaccgtac
    19381 tctttaacgg tagcgctcca ttcagtgcca gcagagacaa cacacctacg gcaattcctg
    19441 caataccacc gaatttataa atgcggttca ttttctcctg catcaataca tttttctctt
    19501 caaaagtagt tgaagagtct gttacttctt ttttcttgtt aaaaccggga agttttaatc
    19561 ctgagagttt aaaccccatt gcgcattacc tctgctgaat taacaggttc gctttttccg
    19621 gataccggag gttgtttatg tgacgcctgg catccgacaa ggcaaagcgt cacgatagcc
    19681 gtgataagta gtttcataat gtgagaacct aaatagagga gtgaatattt actgcggaat
    19741 actcagagtt gacagattta aataataaat cggttaacct ccatatttct ttttcgccgc
    19801 atctatcgca gcctggcgaa gcctcttagc gccaatatta acgccctgcc cggtcagatt
    19861 ccccaactta ccggatacac caggagactg gttgaaccct ccatcctgac ggcgaacgcc
    19921 tttccatgcg ccaatccctg catttttacc cataccaagc agattacgcc ccatacggga
    19981 agcgccgaac acgccagcac caatccccat tgcggctgcc ccttgcatcg cgccttcaac
    20041 acctacccct gcgagctggg aagcataggt tttggcttgc cagataatcc aggccataaa
    20101 tgcacctgca accccggcct gagcacctgt tgatatcaga tttaattcat ctgcgttagc
    20161 tatcgagatt gtcagaatgc cattaaggaa cgtcattccc gctttaattg ccagtccaca
    20221 aaacaagaat atgaagcatg agctaaatat taactgaagc cagctattaa acatctgcct
    20281 taaaaaacca aatgaaagac aaataataaa caacggcgcg gtaatagtaa gtatcttaat
    20341 agtaacttcg gcggcgagat aaactattga agttagcaat aatgcaatta tccctccagc
    20401 atatgttaat aaagatgcga ttgccccatc tgttttcaca tacttcgaag tatctttgga
    20461 cataagatat gcagctacct gctgaacttt ctcccaaagc tcgtcaaccc atttccaagg
    20521 atcacctcct gcaaatgttt ccttcagccc atcaatggcc tgagttgcac tatctaacca
    20581 cccccccata tttttgacaa aaacaagaat taaccagaat cgacatagat tccataaaaa
    20641 atcctgcact gcggtttttt gcttcccaac tattgtggta taagcatacc acaatatata
    20701 aatggaaata ccatacttac ccaactgaga cgctattgaa gaaaagttat ctaactgacc
    20761 agtcaaagac tggtcaagag ttttaacaat aacgtcatga gcggcctgga aatacctaga
    20821 agttgccata gtggctcctt ttaacttcca tctttaccca atacattttt gaatgcatct
    20881 ttatagtcaa catgcttagg atgtaattgc ttatacctaa acaaaccttc cttagcgttt
    20941 ttacaatttt cgctatcact cccagacttt ttgcattcag ctactttttt cgttgcatcg
    21001 tctacgtgag actgccacca gtctacagat ttaacctctt cacacccggt aagaaagaat
    21061 gtaagcccca acgccgcaac taatccatat tttttcaaaa tgccccctca gttcatttca
    21121 taactctgct gctcaaatgc tgccttataa tcaacaactg gagtttcttt attaacagcc
    21181 cctaattgtt tctcctggaa agcagcctgt aacattttct ccttgtattc tgcaagatcg
    21241 cgctgcttat cgcgatacat ttcatactga aatttgagct tgttaaattt caggcttgcc
    21301 agagatacag cgtttgtcgc gtcctgcgtg gctttcgtgt cctgggcgtt cttcacctgg
    21361 tcgataaggt cggccatttc ctgattatct tcacgcagtt tactttccag cttattgccg
    21421 tactcgatcc ccgccagttg ggacaggaac gaggcttcac agccccgcac caggtcgccc
    21481 gtatatccca gccccttaca ggtgtttgtc accttataat cggccagtag tgatctggct
    21541 tgctcagaca gggtggcttc cgggttctta atgtaatcat caatgaagga gttcccctgg
    21601 tcgtaaatat tctccagctc cttactgaca gattgcgcag actgcaccag tccctgaaca
    21661 tcacgaatgc ccgttttggt cagcagctcc tgcttatagg cattaatctg tttctggtag
    21721 tggttcacgg tgtcctgcca ctgtttgagg cgttctgtcc agcgctgcgc ttcgacagcc
    21781 cattcagggt ttgcatcaat ggcaacggga acaccagcct gagcaccaga aataaccgta
    21841 acagaggcga taagtgccgc aacgatatgc tttttcatag ggattcctta aatcaggttt
    21901 gcacgttcca gataggtatc aagccactct tccggcttca taccctcttt ccagatttca
    21961 tcgaacagtt caagctgggg tttcgatgcg ctgagaaccg gtaggtaata cgccgctttt
    22021 cccaaatcca gtcttgcgaa agccgcaaaa tcatcacttt cccccttcct ctgtgggttt
    22081 ttgacgacca ggaactgacg agataacggg tcaatggctt taattttgtc aaaataaagt
    22141 tctctcactt ccaactcgtc tacgtactca ctacgtttcg ctttggggtt cgccagataa
    22201 atatgtgttg cgcactgctc acgaacggca gccgcgatag gtgatttaat tagttcatcc
    22261 ggcgattgtg tcgctacgac aagcaccata tccagcttac gcgcggtttt gagtttgtta
    22321 taaacaaaat ctctgaacgc ttcgttgtta atccattgcc agaactcatc catgtagata
    22381 aggagtcggc ggccatcagc cagcatggtg acacggtaga tgagatagaa tgaagcggcg
    22441 ctggaaagta ctttgttatc cagaaactcc gttccgtcta taccgaaaac gtccaggttg
    22501 tccacatcaa acgtatcgtc cgggttatca aacacccagc caaattcccc tccctgcacc
    22561 caggcattca ggcgtgcttt aagcccatgc cgccgggttt cagtatcatc aggctccaga
    22621 atgagtggtc gcaacttact gatcggataa gagcggtttg acctctgcat caggcgctca
    22681 acggcatcag aaatcaggcg gttctggtaa tcatcaagcg gctcactgtt aagcgtacaa
    22741 agtagcctca ccaggtcttt cataaaggaa atatttcgtt tggttggtgg caaagccgca
    22801 gggttccagc cagtcggctc tccttctttc acccgaaagt aagcacctcc cattgaacgt
    22861 ataccgggtt ccgctgcccg atctttgtcg aaaaatactg tagttaactt ctttaatttc
    22921 ctctcaggtg gaaaagactc cggcgttccg aactgctggg cggcgaaagc cttagtcatc
    22981 atcactaccg ttttacccac gtttgacgta ccaagaattt cggtatgccc cagcgtgggg
    23041 tttttaccga agtaattttg atgctcggta gtcatgtgat agttcaggtt ataaatatca
    23101 tttcctgagc cgcccagggt gataaggttg ttaccccagg tatttccttt ctccttgccc
    23161 gtaaagaaat tatggaagct ttccatttcg gcaaagttca gactgctgat agaactcagg
    23221 cgtggccgta acgtgtagtt accaggtaac tgagcaaaat acgctgcgcc aagactcaag
    23281 gttgaatagg ttacgatcag ccctaaatcc tccagggtcg tcgttacaat attggtgtcc
    23341 ttcaccagac gctccggcga atctgcgtaa acaatcagtg tctggtgact tttcccgaaa
    23401 gaaatatagc cgctggagac catatcgaga ccaactttca aatcagcgag caaggattta
    23461 gcggcatcat cggtcatttc gagtttgtcg atctgatcat ccagcgcctt gattgcagac
    23521 tgcttgtcta tcggagttaa agaggaagtc tgtacatact caaccgggag atacatcagt
    23581 gcatcaaaaa ttccggcatc cgtttcctga aagtagtcct tgatctcgat gcaacgaaag
    23641 taccgggcat ggtcagaggc agtgatttgt ccagcatcgt taccaaagaa caggtcttta
    23701 ccacccaggt atgtataaaa cggactattg gtgactctga ctttctgcca gcgcccggat
    23761 agcagtttct ggaacagcgt aagctgttct gaataaacta tattattttc ttcatataac
    23821 ccaagacgac gggaatgaaa ccgggagaga taggtgctca atctgccaca tatttcattc
    23881 atatcattaa tgggttcttc gaagatattt ttattaccct ttttccttga aagaaaatgc
    23941 gtcactttat cttcagcgct gaacggttta tagcatacgg ttaagtataa tttgttttca
    24001 aaatactcag ccgccgaaag cgattcgtaa taatcgttca tcactctgtt gacgaatggg
    24061 atcttgctgt caaatacagg tcgcacttct tttctaaccc gaatacgatg cgtataaaag
    24121 gtaacgggtt tcccatcaaa actacgtatc agcgtattga gctggtcagt aagcaaggct
    24181 agatccgctt catctacaca ttcaaaataa gctccgtcaa tctgccaggt cgccagtaga
    24241 tcatggtttc tggtaacaat gaggttatca gtgatgtgtg atgaatacgg gattaactct
    24301 tcaagagaag actggtcttt aagcttcata aaattgtcca ctttcgatat atcgactgcg
    24361 tcgtacgaac tccccgcata atggacggca ttgaagcgct tgtttgccag aggattacct
    24421 ttgatttgca ttcgcagata aagcaggtca aaaaagcgtt catctatctt cgtaactcgc
    24481 ttgatggcat accagccagg gaggatgagg gcatacatag cctcatgaat ccagacacca
    24541 agcaaaacgc agataacgca cattccaaga aaggggtaga gcggaacgcc cagcccccta
    24601 atcaaagcgg ggcgtgtcag ccctttaaaa acggtactca tttttacgcc cccttttatt
    24661 acatattacg ctaaccagtc aggcagatat ggcgcaacaa taaagatgat aatcccgata
    24721 attaaaggcg taatccacgc tgcatgctgg cgtgagaaga tagcgatata accaattacc
    24781 agcgcaatga tggtgattgc tggcttacgg atatccgtca gaaaatcgat aatcttctgc
    24841 aagaagccag ttgttttagt ggatacatca tcagcaaagg cgggttctgc tacacaaagc
    24901 atcaatgcag ccataaatac agaaagagtt aaataacgtt tattgagttt taacatcgtt
    24961 tgtttccttt tcatctaaaa cagtgccacg catggcatat tggggatata cggtaacttc
    25021 tttaggtttg atactctgtg ttacattctc ctttctgatt gcatctttaa ctgaaggaac
    25081 cacccagttt tttttgttat caggcggatt aaaccctatg cgctgtatat aactggtgtt
    25141 attaaaatct gattcaggtt tagttcctgt ttctggattg ccggaataat agcaactcag
    25201 gccacgtaaa atatcgccac cacgtttata acaatccacc aaaatttgct ctgaaacctt
    25261 gagattttcg caggggtcaa acattttctc agcggttgta ttgaagtttg caaaattcgt
    25321 actcgttatt tgcataagac cgactgagta acgatgattt cgtgattcaa tttgatttac
    25381 gatctggagt gcagcctcct tagttttggg aaagtaggac actacgcctt tgtcaccggg
    25441 cttacgttca accttcggta ttatctcggc aatagcatat gggttaaaac cagattcaac
    25501 ccttgcaact tcatgcgcag tatcgggatg aacgctggcc gcgcattgca aagcaagcgc
    25561 cgcaaaagca gtagtagata acatgatttt ctcccggcca gaacagcgcg gaaagtttag
    25621 actgaatggt tagtcatcga agtcgtcatc gtcttcatcg tcttcgttta tcagctcctc
    25681 aatagcctgg ctggaatatt tttttatgag gtactggaca acaccagagc ttgaaatacg
    25741 tcgccccctg cgatagccaa tctccagagc aattttatcc agttcctcac gagaagctga
    25801 gggcaggtag agtgtattac gttggggctt gcgtctcgtt gcggtttttt ttcgggtagc
    25861 agtcattttt cttccgtttc attttgtggg ttaagcttct ctctgtgatg tagtggatga
    25921 aagccatact tctttgctgc ggattatcca tgagtagaat ttcagcaaaa tcgtgtggaa
    25981 ttgatttcct taaaagattt gcctgagctg ttgtatgtga ttgtctgtac aaaagctccg
    26041 ccatcacatc ttctggtaca ggtaaaggct caccgccaaa tgagataaag cgttgtacgt
    26101 aagggatagc agttattgta gtggaatgaa cctcttcaaa atctgcctgg ataaaaagat
    26161 aaccgggaaa aagcggcaaa cgtctttctc gatatgaaat tatcttatcc gggcgacgat
    26221 acctttcagt ctccatagga cagaagtaag agaagttcag gcgttcgaga tgagcaaaaa
    26281 ctgctgcaaa tctcgtagtg gtgaattgca aaacatacca ttccatagtt tttcctttca
    26341 ggcgctctct cgactcggat gaccccgaat cagagaaaaa aaacaaaagg acaaatttac
    26401 atctcataaa aactttatca gctacatgtg ctgcgttcaa ccacacaagc agatctttag
    26461 atcgcattta cgacacattt cattttgttt gtgcttgtat tttatttata tctagataca
    26521 tatgctattt gataacaaaa aagcagatcg attgatcacc atgcgcttat tttatagtca
    26581 agttaactaa attttttacc gctagttact ttttacaaaa actctgctaa caagataaat
    26641 aaatcgatct taatcaataa gttaccggag agtatgaatt atcctaaacg aattccgatt
    26701 ttcactttct gttcgctttg aatcatcgac tgttttattt gcgagaaatt tctcatctgg
    26761 agttgctgtt tcttaatcat ctccgcgctg ttcagcacca gctctttact ggatgaagag
    26821 attctgtcta tgcccttaac ccccaggttc tctagctgcc actcattcct gtgtgcagtc
    26881 ttccagccat gctgtacacc gttcttatca agtgcaggga ttttcacctc cttttgtcct
    26941 aacttcttca gcttaacaag atcacctttc ttaacgttct cgcgagtggt taactcacca
    27001 aaatcagccc cccaatatgt tttctccacg cccttgttca gtgtcttaag ctttatgaaa
    27061 tgctgctttg gtttggtttt atcgttctga taatggtcgt agccaacatc aacaacctca
    27121 taaacgccct tctgtcgttt tggcgctgtt ttgtgcgcat ctttaataga ctggttaagt
    27181 ccatgctgct gcttatgagt ggctttaacg tcatagccct tcatcttcag ctcttcacaa
    27241 aaacctgtac gaatttcccg taaatctttt ttcctgatat cagctcgttt accgtcatta
    27301 tcacgaatac gaaaaacgac atgcacgtgt ggatgttctt ttttgtcgtt atgatagcca
    27361 agcacaaaac gatgatttgg gtacttcttg ttcatcgttt tcctgacaga ctcaagcaga
    27421 tcttcaggtt ttacctttgc tgatacaggc ggtgaaaaca caatattttg ggttactttt
    27481 ttattttcct tacctttatc atcgaaaaca ttttgagggt cattagcacg atctatcatg
    27541 tgctctttag cctcctgaat ctcatcacct ttccatacct gaccgctttc actcatcact
    27601 ggcagctctg actcccggct catatagtca atactgtttc gaactccctg ccgggtaatc
    27661 gcacctcctg agattttgac aacaacctcc ttactggcac ccttgcggtt gatacgttcc
    27721 tgaacgttgc gttgatagtt tttaccacca tttttaactt tatgggcgaa agcagacttg
    27781 cggccagctt cagaggactt acgcttaacc ctgaattcct tgtcaacata aacgcccatg
    27841 attacacctc aaccttgtta gaaacagttc gccctttgca taacataatg tagttttcaa
    27901 actcactttt gagactcatt atctctgaac tcaaccgctc agcgtcctga tagaacccat
    27961 ctttatcaag tactctggca ttatcattaa cgataatata atgaaagttt cgccctattt
    28021 tatctattgc attacggcaa cgattcatca ccagaagttc ctgatcgaaa aaatcaagtt
    28081 cattttcaag tgtcgtctgg attcgataac gacattctct ggataaattc cagccatgac
    28141 gatgagccgc tttctctatt aaagttcttt gtttccctgt caaatacatt gtggttttga
    28201 taaaatcatc attgtctttt gacacattaa catcttcatt tttaaccttg cttttcagta
    28261 aagcattggc aagcagcttc attccttttg ccacggttaa acccggttca tctggataaa
    28321 gtgttttaag acaatcaagt agatcatcat gttggctttc ttcaatcctg aattgaactt
    28381 ttttcataaa actctccaac aagaaccgac tgtaggtcac cgggcaaacg ttgcggaatg
    28441 gcgtcagaga cgtcattttg cggcgtttgc cctatcctgc atcgcagtga actacctcca
    28501 cacataaatt gtgcttcagc gtccatcgaa atgcaaaaaa tgaaaggcta tcgtggctgt
    28561 gatctggtgc gtctgcgacc ggagacaacg gattcgcggc taacttgggc ggaaataaat
    28621 tcgctacgcg aatggcctgg cagggggcgc gagcgctgtt ttacggaata tacaaaaaaa
    28681 gcacctcccg taaacgggag ggcttcggcg attcaggaac gggaatttta ttctgcctct
    28741 ggtgtgtcgc cttccatgcc ctgccgggca tcatggagcc agcggcggag gttactcatt
    28801 ctttcccggt ttgcccggct gggacttttt cccctgttac cgcttagtat actccagact
    28861 cttaacccgg cctcgttagt ccagtgcaat acaatttccc ctttgctgtt aaatcccagc
    28921 gaaaaccgga cagctccccg cctctgttct gcactgataa aatctaaaaa ctcctgtttt
    28981 ttcatagcac ctcctgtttt tctatcagtg cttttgtttc tttcttttcc agggcttttc
    29041 tgagtaatgc catgtactca ggaaaagcag agaatggcat caagggaaaa accggacgcc
    29101 cacccttttc aacagtctgt attgctgata acatgcgttc cgacatttta tattcctcgc
    29161 gagggaattg agtgtcacgg tatcaggttg cctccacaac ctgataccac ccctaattga
    29221 ttaactccgc agttctctta tcgcttcatt tttggcttcc tccagttctt taagggtata
    29281 tgcgaaattc ttccagttaa ttacttcgtt tataacctca gatttactta aaccacactc
    29341 attaaaccaa aagttaatat ttttcttgag ggaatttttc gccgtcagtt cctcggacaa
    29401 caattcacta acagacgtga taacataacc acgaccgcga tttttatctt cgaaagaatg
    29461 aacggcaagg aagagagttt ctgaatggac aaaagcagag caggtgattt tttctttctt
    29521 agtgtttaaa gcctggaaag tgataacata cgtgttcatt ttagtctccc gcccgtttgg
    29581 gctactggat catggtaagg aactattccc gacctacaaa taaattatac catcatatga
    29641 tggtaatgca atttatttag tcactttatc ctgatttttt tctctcttaa cgagctggta
    29701 atctggatgt tcatcagcca ggagcaaaag taattcatac gtaccagcgg ctaaaccacg
    29761 agacgtttta ccggatgttt ctttggcttg ccaggctgat aacgtaaaac caaaccgttc
    29821 agcggcttcc tgctgcgtaa agccagcttt aatacgtgct tgtttcacct cttcaggtgt
    29881 tggcttaaaa ctcatgattt tgtaccttca caatagtatc tgtatagaat ttcaataaaa
    29941 ttggatcatc aatttcatct ttaacgttcg agaattcttc gtaataaaat gatttttgga
    30001 aaacaatctt tttagttgtt tttttatccg cttctttaga gcgtaccttc atcagttttt
    30061 caagttcaat aaacaaacgt gttgcatctt cagacacaac aatcctgtat gttacattac
    30121 ctttgttttt cctgtcgctc aggacttcat tcattttttg cctcatagct gtttaataaa
    30181 ccccgctacc tttatgagct gatctacact caggccacga attaccattt catatccgtc
    30241 gccccgttct gatacgttac catctaaccc attctcaact ttaaacccgg tcaatgtccc
    30301 atgccagctt tcaagatgca ctaaacgaga tagcattcct ttcaggatca gttttttctc
    30361 gcgtttttgc tgtaactgtt gttcatactc tcgcgccata tctacattat ctaaagcatc
    30421 cgacaggatt ttcttttcaa tatcggcggc gatttctaca gggttacgct ctggcgatac
    30481 tgtgcaagta tggtaaggac ttctccagct gcgactatct acgcttccaa tgataactaa
    30541 ccttcctttc tccattcgaa tatgtataga gtaattttta aaatcaggtg aggttagctt
    30601 aatcctgtac tggcaatcat cgagcagatt tacacgccag ccgttcccca ggattcgaca
    30661 aacgatttca aacaccggtt tataccgttc aaagaaattt ttctgttctt tcatcgattc
    30721 agccttttga actcaataaa aaagccgtaa atcgaattac ggcagtttta agactattca
    30781 tcaaagtgtc catcatcact tgcagcttcc tgggcttcgc attcctgctg atatgcttct
    30841 tccttcgcaa aaagatgcgc ccatccttct gcgtttaagc cacggtgcaa gactgaacca
    30901 ttttcattgc attctttggc tgtaacttcg atctcatccg ggcaaatgta ggctccgtaa
    30961 ctttcaaaaa tgtttatcag ctccgcttcc gttatggtct tgtttttcat caacgtgtct
    31021 ccgaatcaat ctttgccatg ttctaggggg ctttcgcccc cattccggtt atgcgcttgc
    31081 ttctacacgt gtccagcctg acgccttacg tttacccgct gtaccataca tttcacgaat
    31141 ttcttcaatg ctgtgttctt tacggttcca gcggcttttg tgttcttcag gacggtaaaa
    31201 ccattgtttt ttcttagatg cccacttaca gcccatttcc tttaaaatgt ctttgtgttc
    31261 tttagtttct ccgctaatcc agacccaatt accaataact tcatagacaa tccctgtaag
    31321 gccggaaagc gtattcagaa ctttttccag atcttcaccg tagttgtaac gtgcgttttc
    31381 atcagtgctt tgaaactgat tgattttatc aatgttagcc atgagaaaat caaacgcagc
    31441 atttactgct ttcatcagct cggcacccaa tggattgcgg tctggatgat attttaaagc
    31501 cgcttttttg tatgccgcct tgatgtcctt ttcagtcaga tcaccggata aaccaaaaac
    31561 gtttaatgct tcctgaatat tcatttttcg ctcccgcccg tgtgggcttc tggaatctgg
    31621 cagggaacca ttcccaacca acaaattcat tataccatca aatgatggtt atggaatcat
    31681 ttttaatgct ttacattgta aagattacat aaagatgtat attgctttac cgcgcatgaa
    31741 gggatttccg aaagaggcgc gaactgtagt tacataatgc gctgtcgtaa catcgcgccg
    31801 gagacgttcg ccaggactgg cgaaccaaca agcccgaatg agagcgataa cccccctcac
    31861 ccctgccagg ccaatttctg actatcagac gatgtttagc ctgtcgcagt tagcgcgtga
    31921 gcttgcgaac ggtacgccgg gtcagtgtga aacactggcg cggggcgctg tatctgcgcg
    31981 ttatgagatg cgttagcagc gaattacggg gcgggttgct gaaaccgatt gatgcctgac
    32041 agcaaaaaat gaatccgggc gccagctgct gcacgaaaat tgccagcaaa aaacacttgg
    32101 ccatcctcgc cggtcgtgaa attttgctgg cgtaagaaat aatccccccg gtatgagggg
    32161 cttgtctgaa aggttagtgg ttgggcttac tgagagtgaa ctgtaacccg gctactgctg
    32221 caagctgtgc aagtgttgtg atggtcgggt ttccgttcgg ggataatgcg cggtagatac
    32281 tctgacgagc aaggccggat tttttggccg cctctgttat accccctgat tagggatcag
    32341 gttaaaaacg agctgtatga cgttctaagc gcattttacc cgctccgttg aaccatgacc
    32401 gggttaaagc ggttaaaacg cctctgaggg cttttgagag catttaagaa ttggatcgga
    32461 aaaggatccc gtctggatct tttagagaga ttacaccgct cgccgcagcc gaacgacagg
    32521 gcgaagcccg cgagtgagcg aggaagcgga atttccacgg ggtttcaata gagcacttac
    32581 gcgctaaggt taatatttgc tcaatttttg gtggtgcagt gctcagggag gccagacgga
    32641 tctatcctct ggatttatgc tgagttatcc acagacgctg tgcattaaaa gccttatatt
    32701 ttcttcttga tcttaaaaac ttaaaaactt agctcgcttc aattacctga aaattatgga
    32761 aaaaaattgc taaaggtgag aggatttttc acgtaaggtg agaggatttt tcacgtaagg
    32821 tgagaagatt tttaagttaa ggtagttaga tttttcacta aagatgagag gatttttcac
    32881 gtaaggtgag aagattttta acggtttcca cagtttgact gaacatcaag tgaaacatgc
    32941 ggttgttgct atctttagat atgaagatcc tcagatcttc atatctaaag gtgagaggtt
    33001 ttttaattaa aggttgtatt gttgtcttga attacaacct ttgtggggtt atgatttgcc
    33061 tacataggaa aggttatatg aggcttatcg tgaagacagt aacgggatta acgaaagtta
    33121 gacatagaaa tgaagttggg gtaactcttg catccctttc cctttcagca aaaagagtgc
    33181 tttttctggc tctttgccag attgatacaa aggaaatgtt agatgatgat attttggagg
    33241 ttgatgctga ctttttttca aaagctactt ctttagataa atatgcctct tatgcagctc
    33301 tgaaagaggg agctaaagtt ctttcttcaa ctacgttagt tttaaacaga gatgatttaa
    33361 aaaatttggc tgatgaactt gggatactat catctaagaa taaaatacct gatcgcttgg
    33421 atttaaactt aacagaattc tgtgcctatt acgatcatct tgcaactgta cggataaaat
    33481 tcacaaatac agctaagcga tatttttcta agttgattgg ttctgaaaat agatatacca
    33541 ctcaggtatt gaaatcagtt gtgttgttga acagtgtaaa ctcaacaaac ctttatcaag
    33601 tcattaggaa atattacagt cagaatagtt caaaaaaatc ttttgatata tccgtggatg
    33661 atttaaaaga ggaaatggga ctttatacta ttgaggaagg ggagaagaaa tataagtatc
    33721 ctaaatactc attttttgtt cgtgatgtta tcaataaaag cattaatgag ataattgaga
    33781 aaacggaaat aaatcagtta tctttctctg ttgttgggaa aaaagggaga atggctcaca
    33841 tgcttagatt tgagtttagt ataaatgaaa aatcctcatc cttttcggaa gatgatatgg
    33901 catttttaga ggagtttgac aaagtcgttc caccaaaaaa gaataagtga ggcaaaacat
    33961 ggctaaaata tatgagtttc cgcagggagc cgaacgaagt aagctgaaaa aagaaatcat
    34021 ccgggaacgt aaaaaacgat tgcgagaaac gaacggtaac ccggttatcc ggcacgctaa
    34081 atggttctgg ttttatctac gtcttgctac ggctggcgca ctgcatttag tctctgttat
    34141 ttctctggca gtcctggggg ctttcagtaa agctattttc tggattggtg gaatgctctg
    34201 tgttgttaca tggttccacc ttgagcgcca gttctggacg ccgcaaaatt tcacgattcc
    34261 agtaatcgta acgctgtggg gattgagttt gtttgccact cccctgatgg agctgcttaa
    34321 caaaaaaatg ccgtggtatc gtcttctggt tcctgatgca aagcacacta gcactgaggc
    34381 aaccaatgat gatcagccgt gaagcaacaa tgttatccag tcggcttgca gtgcttcttt
    34441 cagcctttta tcatcggtta atcatagcgc acgaggcgag ttcttttcac tgcgatgcag
    34501 gatagggcaa acgccgcaaa atgacgtctc tgacgccatt ccgcaacgtt tgcccggtga
    34561 cctacagtcg gttcttgttg gagagagtta tgaaatatca ggttaaagag tttattaacg
    34621 aaaaatattc taaggctgtt aatattttaa aggataacct taaagaacac taccatattt
    34681 tttatggttt gagattaagt gagattcttt ttcctgccag cgaatacggc tctgaaatgt
    34741 tttttcagga gtttgaagcg attaacagtg taatattgcc tttggtgatt tttgatttga
    34801 tagaccgaaa gccgattatg gttatcggct tcggtgaagt atgtggagtt gattcacttg
    34861 ttgattctgg tatagaagtt gtttctttag acggtttaag cgatctgcta ctggttgaaa
    34921 aactgacgcc attatttaac taaacctctg gataactatc ttttcagttt tccagtaaga
    34981 ttttttctat atctgaaagc actatttttt caatgctttc tatatagtaa tgctcattaa
    35041 aacctgtcat ttctgtaaat tttagctctg catcatcttt cgaataagca ataacaactc
    35101 tgaaatcatt ttcccacaaa tcccacctgt atttgtcttt tatacgaacc ctgtacaatc
    35161 ctttttggat agtgccatct tttttctctt cctgtacttt ttttaatttt tcattttgca
    35221 cctgttgttc aagccatgat ttattcataa atcccccacg gttaacgtct ttaggctcgg
    35281 tttttactta acgaaatctt ccggttttac acctgttttt accttcatat acttgccctc
    35341 cccccttagc ttcggctgaa gttcggtaaa gtaccatccg gcaacggtaa taatgcctaa
    35401 aaatacaaaa atagcaggct tcagaacatc aatagctgat acagcgcata actcaatatt
    35461 gagattagta caagttccct catcaggtgc atagaacccc cataagccta tacctataag
    35521 gaacatcccc aatatcggtt ggatgtataa caagtagata ttaataagag ttttaatata
    35581 tctgaatatg aacatttttc tttccttagg tttctttcta ttttggattt ccaattctta
    35641 accaatgtga tggttcgaca atccattctc cgcagtcata ggcaacggcc ttattatgcc
    35701 tgttagcgaa ccatactaac caggctaata atcgctgatt gccgctgtat ttggtttatc
    35761 tctaaccatc acaacatatc tctttttctt agccataacg ctaccctaat tttgcagatt
    35821 caagcagcca gtggtttttc aggttctcgt ccaggttatc gaatgcggcc agcgctgcct
    35881 ttagaacggt tgtcttgctc tggcctgttc tctgcgcctc cgcttccagg atctcctcaa
    35941 agtacgctgg cagtctgaag ttcatcaact ttggtttacc cgctacaggc gctctggtag
    36001 cgccggagat aaaacgcgcg gtttctgcgt ttgttgctgg ttgctgagat tcatcgatgt
    36061 tcgggcggtt tagttttaaa gccatgaaaa tttccccttg tacggtatgc attaattgta
    36121 aatatcatag tatctttatg gtgtatttac aatgtaaaga tttcgatgaa tattgttgat
    36181 atttctataa aatgccaatt tcctgtgcca caagttcaat ctgtgctttc gctgttgaaa
    36241 ggctcgatgc ccggctaacg tcatgtaccc ctgccccttc attacaggcg ctttcataca
    36301 catccagctc ggatatccgg gttttcagag gttgaatcca gatgttgtcc gaacgcagta
    36361 atttatccag atcaatggcc gcttttctgt ggcggggttt cgctgagttg attctggtga
    36421 acagcaccca cggttccaga gctgcgttag ctttctgagc ggtgcggatt ttctctgtaa
    36481 cactggtcag tgtttcgctt tcgaaatcag aggacggctt aaccagtgtc accacgatat
    36541 ctgatactgt cagggcgcta cggaactcct ggctgtcgtg gccggggcaa tcgacaatga
    36601 gaacttcaca cagcttacta aggcgcttaa tttcgttgct gacgtttccg taagctgcgt
    36661 gaaccgggat agtgagtaag ccgttatctg tccgcttttc gttccagctc aacagatcgt
    36721 ggtttttatc tgtcttcagg ataattaccg acttaccttt gttgaccagc attgagcctg
    36781 tgttagccac gtaggtgctt ttgcctaccc cacctttatc tgatacgaca agcaagattt
    36841 tacccatttc agaatccctc tctttatgtt gtaaagctca tgtaaagata tgaatgtctt
    36901 tacatggtgt gtttttcgta aagatacttt tgtctttaca gtgtctttat aatgcaatgg
    36961 ctttaccatg taaagcacaa ataaagatat atttatcttt atggtgtctt tacatggtaa
    37021 atgttgctgt gtctttatgt gcgctttatg gtgtaaatct tggtgtgtct ttacatcatc
    37081 tttatgttgt aaatttttag tgtgacgttg tcactatagg gctggggtct gtttgctggt
    37141 tctttttgag tgtgccttcc ctgaaccaac tgaaatgggt actgtatggg tgtgtctggt
    37201 taactcaaaa tgaactggtt ccctataatg actcaaacag taccgaaagg ctttgtcaga
    37261 gcttacttac gcgcatccac gactgaacag gatgcaacac gcgccctgga cacgataaat
    37321 accttcgcca tcgagcgcgg cctgagcatc tgtaactact acattgaaaa tgaatcaggt
    37381 tctaagcttg aacgccctga gttgttccgg ctcctgaaag attgtcagca aaacgatatc
    37441 ttgctggtag aggatgtgga caggctttca cgcctggtag gggaggactg gaacacactg
    37501 aagaaaatga tccggcagaa agatatccgg gttgtggccg tcaacgttcc gacaacctgg
    37561 ctcgcatcgg gtcacaatga ttttgacagc cgaatgtttt cggccataaa cgatatgttg
    37621 ctggatatgc tggccgccgt cgccaggcga gactatgaac agcgccggga acggcagcag
    37681 caggggatcg ccagggcgaa aagggaaggg aagtataaag gccgccaggt taatcagtct
    37741 cgctatgacg ccataaacag gctgattgcg agcggcagct cctggagcca gattcaaaaa
    37801 gtgctgggtt gtagccgggc gactatcagc aaagctgtga agcaacagac cgttaacaaa
    37861 atgaaccatg aacctgaagg tagggagtag ttacaacata ataaacagtg tgttgaagaa
    37921 taaaactgat tctttatact gtatatg
//
LOCUS       DACAOP010000039        36974 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.039, whole genome shotgun sequence.
ACCESSION   DACAOP010000039 DACAOP010000000
VERSION     DACAOP010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36974
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.039"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            280..1338
                     /gene="citC"
                     /locus_tag="IT892_002205"
     CDS             280..1338
                     /gene="citC"
                     /locus_tag="IT892_002205"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415151.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HAP3135419.1"
                     /translation="MFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTR
                     DEKLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYE
                     ALFRQCGFSTLTSVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIVMNANPFTNG
                     HRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRGSEYIISR
                     ATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMR
                     YWLETPTISAPPIELVEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQ
                     NLLEHSRQDAAARQKTPA"
     gene            1353..1649
                     /gene="citD"
                     /locus_tag="IT892_002206"
     CDS             1353..1649
                     /gene="citD"
                     /locus_tag="IT892_002206"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HAP3135420.1"
                     /translation="MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDA
                     IRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ"
     gene            1646..2554
                     /gene="citE"
                     /locus_tag="IT892_002207"
     CDS             1646..2554
                     /gene="citE"
                     /locus_tag="IT892_002207"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415149.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HAP3135421.1"
                     /translation="MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLE
                     DSVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRL
                     PKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGI
                     ALGAEDYVRNLRTERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEA
                     AHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNG
                     KMVDGPVIDRARLVLSRAELSGIREE"
     gene            2565..4097
                     /gene="citF"
                     /locus_tag="IT892_002208"
     CDS             2565..4097
                     /gene="citF"
                     /locus_tag="IT892_002208"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HAP3135422.1"
                     /translation="MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDR
                     KLCANLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNMVMDVIAKMGFKNLTLASSSLSD
                     CHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNI
                     DVAFLGVPSCDEFGNANGYTGKACCGSLGYAMVDADNAKQVVMLTEELLPYPHNPASI
                     EQDQVDLIVKVDRVGDAAKIGAGATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQT
                     GTGGASLAVTRFLEDKMRSRDIRADFALGGITATMVDLHEKGLIRKLLDVQSFDSHAA
                     QSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRG
                     ASGGHCDTAIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPAR
                     PELAERLQEAGIKVVSIEWLRERARLLTGEPQPIEFTDRVVAVVRYRDGSVIDVVHQV
                     KE"
     gene            4101..4652
                     /gene="citX"
                     /locus_tag="IT892_002209"
     CDS             4101..4652
                     /gene="citX"
                     /locus_tag="IT892_002209"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HAP3135423.1"
                     /translation="MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFT
                     VVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPAR
                     DLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQSAAVCARGKT
                     HQLTDLLNRMEALLNDVDACNVN"
     gene            4627..5505
                     /gene="citG"
                     /locus_tag="IT892_002210"
     CDS             4627..5505
                     /gene="citG"
                     /locus_tag="IT892_002210"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HAP3135424.1"
                     /translation="MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDR
                     INCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDM
                     FRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
                     NSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLL
                     LMAINGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSP
                     GGSADLLILTWFLAQI"
     gene            5556..7019
                     /gene="citT"
                     /locus_tag="IT892_002211"
     CDS             5556..7019
                     /gene="citT"
                     /locus_tag="IT892_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/succinate antiporter CitT"
                     /protein_id="HAP3135425.1"
                     /translation="MSLAKDNIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAM
                     IVGMILEPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSST
                     TVWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNT
                     ARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVL
                     GLEFVSKIAGIQISWLQWFLCFLPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDE
                     LKTMGALTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKDITR
                     YNSAWNTLVNLATLVVMANGLTRSGFIDWFAGTMSTHLEGFSPNATVIVLVLVFYFAH
                     YLFASLSAHTATMLPVILAVGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIY
                     GCGYVKSKDYWRLGAIFGVIYISMLLLVGWPILAMWN"
     gene            7133..7939
                     /gene="rna"
                     /locus_tag="IT892_002212"
     CDS             7133..7939
                     /gene="rna"
                     /locus_tag="IT892_002212"
                     /EC_number="4.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease I"
                     /protein_id="HAP3135426.1"
                     /translation="MKAFWRNAALLAVSLLPFSSANALALQAKQYGDFDRYVLALSWQ
                     TGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGLWPGLPKSVAARGVDERRWMRFG
                     CATRPIPNLPEARASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACF
                     GFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKL
                     TCQGNPAYLTEIQISIKADAINAPLSANSFLPQPHPGNCGKTFVIDKAGY"
     gene            8169..8579
                     /gene="rnk"
                     /locus_tag="IT892_002213"
     CDS             8169..8579
                     /gene="rnk"
                     /locus_tag="IT892_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HAP3135427.1"
                     /translation="MSRPTIIINDLDAERIDILLEQPAYAGLPIADALNAELDRAQMC
                     SPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAKMTDSNTQLSVMAPVGAALLGLR
                     VGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL"
     gene            complement(8810..10048)
                     /locus_tag="IT892_002214"
     CDS             complement(8810..10048)
                     /locus_tag="IT892_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde
                     dehydrogenase"
                     /protein_id="HAP3135428.1"
                     /translation="MKALTYHGPHHVQVENVPDPGVEQADDIILRITATAICGSDLHL
                     YRGKIPQVKHGDIFGHEFMGEVVETGKDVKNLQKGDRVVIPFVIACGDCFFCRLQQYA
                     ACENTNAGKGAALNKKQIPAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
                     SDDKALFLSDILPTAWQAAKNAQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVD
                     HHPYRLHFAADRYGAIPINFDEDSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTET
                     VLTNLKLEGSSGKALRQCIAAVRRGGIVSVPGVYAGFIHGFLFGDAFDKGLSFKMGQT
                     HVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAQS
                     AEAAQKAVSGLVNAMPGGTI"
     gene            10269..10697
                     /gene="uspG"
                     /locus_tag="IT892_002215"
     CDS             10269..10697
                     /gene="uspG"
                     /locus_tag="IT892_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspG"
                     /protein_id="HAP3135429.1"
                     /translation="MYKTIIMPVDVFEMELSDKAVRHAEFLAQDDGVIHLLHVLPGSA
                     SLSLHRFAADVRRFEEHLQHEAQERLQTMVSHFTIDPSRIKQHVRFGSVRDEVNELAE
                     ELGADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR"
     gene            complement(10818..12383)
                     /gene="ahpF"
                     /locus_tag="IT892_002216"
     CDS             complement(10818..12383)
                     /gene="ahpF"
                     /locus_tag="IT892_002216"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAP3135430.1"
                     /translation="MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIA
                     ELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPS
                     KEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQ
                     NEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIV
                     GSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVH
                     VDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNMNVPGE
                     DQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKA
                     DQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIG
                     LLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKAS
                     LSAFDYLIRTKTA"
     gene            complement(12628..13191)
                     /gene="ahpC"
                     /locus_tag="IT892_002217"
     CDS             complement(12628..13191)
                     /gene="ahpC"
                     /locus_tag="IT892_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HAP3135431.1"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAS
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     gene            13563..14309
                     /gene="dsbG"
                     /locus_tag="IT892_002218"
     CDS             13563..14309
                     /gene="dsbG"
                     /locus_tag="IT892_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbG"
                     /protein_id="HAP3135432.1"
                     /translation="MLKKILLLALLPAIAFAEELPAPVKAIEKQGITIIKTFDAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNTLIEKEIYAPAGREMWQRME
                     QSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESP
                     ATAAAILASKDPAKTWQQYEASGGKLKLNVPANVSTEQMKVLSDNEKLMDDLGANVTP
                     AIYYMSKENTLQQAVGLPDQKTLNIIMGNK"
     gene            14518..15420
                     /locus_tag="IT892_002219"
     CDS             14518..15420
                     /locus_tag="IT892_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3135433.1"
                     /translation="MANLYDLKKFDLNLLVIFECIYQHLSISKAAESLYITPSAVSQS
                     LQRLRAQFNDPLFIRSGKGIAPTTTGLNLHHHLEKNLRGLEQTINIVNKSELKKNFII
                     YGPQLISCSNNSMLIRCLRQDSSVEIECHDILMSAENAEELLVHRKADLVITQMPVIS
                     RSVICMPLHTIRNTLICSNRHPRITDNSTYEQIMAEEFTQLISKSAGVDDIQMEIDER
                     FMNRKISFRGFSLLTIINSIAVTDLLGIVPYELYNSYRDFLNLKEIKLEHPLPSIKLY
                     ISYNKSSLNNLVFSRFIDRLNESF"
     gene            15567..16787
                     /locus_tag="IT892_002220"
     CDS             15567..16787
                     /locus_tag="IT892_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HAP3135434.1"
                     /translation="MSIYKIPLPLNILEAARERITWTLNTLPRVCVSFSGGKDSGLML
                     HLTAELARQMGKKICVLFIDWEAQFSCTINYVQSLRELYTDVIEEFYWVALPLTTQNS
                     LSQYQPEWQCWEPDVEWVRQPPQDAITDPDFFSFYQPGMTFEQFVREFAEWFSQKRPA
                     AMMIGIRADESYNRFVAIASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTW
                     YANHQSLCNPLYNLMYQAGVPLRHMRICEPFGPEQRQGLWLYHVIEPDRWAAMCARVS
                     GVKSGGIYAGHDNHFYGHRKILKPEHLDWQEYALLLLNSMPEKTAEHYRNKIAIYLHW
                     YQKKGIEVPQTQQGDIGAKDIPSWRRICKVLLNNDYWCRALSFSPTKSKNYQRYNERI
                     KGKRQEWGILCNND"
     gene            16760..17389
                     /locus_tag="IT892_002221"
     CDS             16760..17389
                     /locus_tag="IT892_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HAP3135435.1"
                     /translation="MGDTMQQRLTQDLTQFLASLPEDDRIKAINEIRMAIHQVSPFRE
                     EPVDCVLWVKNSQLMPNDYNPNNVAPPEKKLLQKSIEIDGFTQPIVVTHTDKNAMEIV
                     DGFHRHEIGKGSSSLKLRLKGYLPVTCLEGTRNQRIAATIRHNRARGRHQITAMSEIV
                     RELSQLGWDDNKIGKELGMDSDEVLRLKQINGLQELFADRQYSRAWTVK"
     gene            complement(17390..18550)
                     /gene="ybdL"
                     /locus_tag="IT892_002222"
     CDS             complement(17390..18550)
                     /gene="ybdL"
                     /locus_tag="IT892_002222"
                     /EC_number="2.6.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine-oxo-acid transaminase"
                     /protein_id="HAP3135436.1"
                     /translation="MTNNPLIPQSKLPQLGTTIFTQMSALAQQHQAINLSQGFPDFDG
                     PRYLQERLAHHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATE
                     ALYAAITALVRNGDEVICFDPSYDSYAPAIALSGGIVKRMALQPPHFRVDWQEFAALL
                     SERTRLVILNTPHNPSATVWQQADFAALWQAIAGHEIFVISDEVYEHINFSQQGHASV
                     LAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLA
                     LADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYSAVSTLDD
                     VEFCQWLTQEHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL"
     gene            18659..19747
                     /gene="hcxA"
                     /locus_tag="IT892_002223"
     CDS             18659..19747
                     /gene="hcxA"
                     /locus_tag="IT892_002223"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcxA"
                     /protein_id="HAP3135437.1"
                     /translation="MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGKR
                     AIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTA
                     KALARRLGLPFVAVPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
                     NAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALS
                     DQQNQQLTQSFCDVVDAIIAGGGMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQAEIDKVIAHTLRP
                     VESIHYLPVTLTPDTLRAAFKKVESFKA"
     gene            complement(19757..19954)
                     /locus_tag="IT892_002224"
     CDS             complement(19757..19954)
                     /locus_tag="IT892_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HAP3135438.1"
                     /translation="MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     gene            complement(20137..22242)
                     /gene="cstA"
                     /locus_tag="IT892_002225"
     CDS             complement(20137..22242)
                     /gene="cstA"
                     /locus_tag="IT892_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein CstA"
                     /protein_id="HAP3135439.1"
                     /translation="MNKSGKYLVWTVLSVMGAFALGYIALNRGEQINALWIVVASVCI
                     YLIAYRFYGLYIAKNVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAG
                     VIALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAESPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGNLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFSITPDTLNQIASEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKVGFLAIANKFQAMIDSG
                     NIPSQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLALFSIKTALAALKDPKPTAKETP
                     YEPMPENVEEIVAQAKGAH"
     gene            complement(22423..22836)
                     /gene="entH"
                     /locus_tag="IT892_002226"
     CDS             complement(22423..22836)
                     /gene="entH"
                     /locus_tag="IT892_002226"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proofreading thioesterase EntH"
                     /protein_id="HAP3135440.1"
                     /translation="MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDT
                     RTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVC
                     QPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG"
     gene            complement(22839..23585)
                     /gene="dhbA"
                     /locus_tag="IT892_002227"
     CDS             complement(22839..23585)
                     /gene="dhbA"
                     /locus_tag="IT892_002227"
                     /EC_number="1.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase"
                     /protein_id="HAP3135441.1"
                     /translation="MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY
                     PFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAV
                     NVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL
                     ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEI
                     ANTILFLASDLASHITLQDIVVDGGSTLGA"
     gene            complement(23585..24442)
                     /gene="entB"
                     /locus_tag="IT892_002228"
     CDS             complement(23585..24442)
                     /gene="entB"
                     /locus_tag="IT892_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis bifunctional
                     isochorismatase/aryl carrier protein EntB"
                     /protein_id="HAP3135442.1"
                     /translation="MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVS
                     FWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADLSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAAL
                     REVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAW
                     WKLLSREVK"
     gene            complement(24456..26066)
                     /gene="entE"
                     /locus_tag="IT892_002229"
     CDS             complement(24456..26066)
                     /gene="entE"
                     /locus_tag="IT892_002229"
                     /EC_number="2.7.7.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase"
                     /protein_id="HAP3135443.1"
                     /translation="MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVID
                     GERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVL
                     ALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLLNDSGE
                     HNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEIC
                     QFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVT
                     ALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGM
                     AEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFR
                     GYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVE
                     CVDSLPLTAVGKVDKKQLRQWLASRASA"
     gene            complement(26076..27251)
                     /gene="entC"
                     /locus_tag="IT892_002230"
     CDS             complement(26076..27251)
                     /gene="entC"
                     /locus_tag="IT892_002230"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase EntC"
                     /protein_id="HAP3135444.1"
                     /translation="MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAV
                     NGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEK
                     QASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDA
                     AIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARR
                     QPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWH
                     LATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWC
                     DSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH"
     gene            27626..28582
                     /gene="fepB"
                     /locus_tag="IT892_002231"
     CDS             27626..28582
                     /gene="fepB"
                     /locus_tag="IT892_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe2+-enterobactin ABC transporter
                     substrate-binding protein"
                     /protein_id="HAP3135445.1"
                     /translation="MRLAPLYRNALLLTGLLLSGIAAVQAADWPRQITDSRGTHTLES
                     QPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLY
                     IGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
                     EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQM
                     LEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQKDADAIY
                     ANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLDRLKALF"
     gene            complement(28586..29836)
                     /gene="entS"
                     /locus_tag="IT892_002232"
     CDS             complement(28586..29836)
                     /gene="entS"
                     /locus_tag="IT892_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin transporter EntS"
                     /protein_id="HAP3135446.1"
                     /translation="MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFR
                     FLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGAL
                     TSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYT
                     MLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGV
                     LLLLVLVELRHFRQTPPQVTASDS"
     gene            29947..30951
                     /gene="fepD"
                     /locus_tag="IT892_002233"
     CDS             29947..30951
                     /gene="fepD"
                     /locus_tag="IT892_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-siderophore ABC transporter permease"
                     /protein_id="HAP3135447.1"
                     /translation="MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAF
                     SGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGAS
                     FAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
                     VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALN
                     SLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAIVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
                     "
     gene            30948..31940
                     /gene="fepG"
                     /locus_tag="IT892_002234"
     CDS             30948..31940
                     /gene="fepG"
                     /locus_tag="IT892_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="HAP3135448.1"
                     /translation="MIYVSRRLLITCLLLVSACVVAGIWGLRSGAVTLETSQVFAALM
                     GDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWS
                     GVLVAMVLFGQDLTAIALSAMVGGIVTSLLVWLLAWRNGIDTFRLIIIGIGLRAMLVA
                     FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLE
                     MGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARW
                     GLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     gene            31937..32752
                     /gene="fepC"
                     /locus_tag="IT892_002235"
     CDS             31937..32752
                     /gene="fepC"
                     /locus_tag="IT892_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter ATP-binding
                     protein"
                     /protein_id="HAP3135449.1"
                     /translation="MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQELV
                     ARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
                     ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALR
                     EGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTANS"
     gene            complement(32749..33882)
                     /gene="fepE"
                     /locus_tag="IT892_002236"
     CDS             complement(32749..33882)
                     /gene="fepE"
                     /locus_tag="IT892_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen length regulator"
                     /protein_id="HAP3135450.1"
                     /translation="MSSLNIKQGSDAHFPDYPLASSSNNEIDLLNLISVLWRAKKTVM
                     AVVFAFACAGLLISFILPQKWTSAAVVTPPEPVQWQELEKSFTKLRVLDLDIKIDRTE
                     AFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDELDLHRAIVALSEKMKAVDDNAS
                     KKKDEPSLYTSWTLSFTAPTSEEAQTVLSGYIDYISTLVVKESLENVRNKLEIKTQFE
                     KEKLAQDRIKTKNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGAD
                     GIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKAHVNDVNFTPFKYQLSPSLPVKKD
                     GPGKAIIVILSALIGGMVACGGVLLRYAMASRKQDAMMADHLV"
     gene            complement(34098..>36974)
                     /locus_tag="IT892_002237"
     CDS             complement(34098..>36974)
                     /locus_tag="IT892_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit F"
                     /protein_id="HAP3135451.1"
                     /translation="GRAAGDEPLFGPVLNIKVFDYQLDIPDVQAQTHTLATGPVNDLE
                     LALFPDVHGDLSIEILANKQRYDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPG
                     EYAQLAQLNATQVEIPETTLSALVAEQAAKTPDAPALADARYLFSYREMREQVVALAN
                     LLRERGVKPGDSVAVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARP
                     SLLITTDDQLPRFSDVPNLTSLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPK
                     GVMVGQTAIVNRLLWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEP
                     EAHRDPLAMQQFFAEYGVTTTHFVPSMLAAFVASLTPQTARQSCATLKQVFCSGEALP
                     ADLCREWQQLTGAPLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLR
                     ILDAMMHPVPPGVAGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVAR
                     WLDNGAVEYLGRSDDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGD
                     ARQLVGYLVSQSGLPLDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKALP
                     LPELKAQAPGRAPKAGSETIIAAAFSSLLGCDVQDADADFFALGGHSLLAMKLAAQLS
                     RQVARQVTPGQVMVASTVAKLATIIDAEEDSTRRMGFETILPLREGNGPTLFCFHPAS
                     GFAWQFSVLSRYLDPQWSIIGIQSPRPNGPMQTAANLDEVCEAHLATLLEQQPHGPYY
                     LLGYSLGGTLAQGIAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEIN
                     REREAFLAAQQGSTSTELFTTIEGNYADAVRLLTTAHSVPFDGKATLFVAERTLQEGM
                     SPERAWSPWIAELDIYRQDCAHVDIISPGTFEKIGPIIRATLNR"
BASE COUNT         8849 a        10131 c         9348 g         8646 t
ORIGIN      
        1 cattaaatca attaaatcac ttaaacctgc gagtcatttc gtaattacat taattaaaaa
       61 acttaaaatc attaaataaa taaaaaacca ctaactctat gtgaaataaa tcaaaatttc
      121 acgccgaaat actccttagg atgtatagcg aaaggagaaa aagatatacc tcgatcaccc
      181 cctttctccc aagtgaaaat aaaaggttat cagtttgcaa cattgaacaa cattcgttgc
      241 aaatcgataa caacatgcac cttcaggata ctatttatta tgttcggcaa tgatattttc
      301 acccgcgtaa aacgttcaga aaataaaaaa atggcggaaa tcgcccaatt cctgcatgaa
      361 aatgatttga gcgttgacac cacagtcgaa gtatttatta ccgtaacccg cgatgaaaag
      421 cttatcgcgt gcggtggaat tgccggaaat attattaaat gcgttgctat cagtgaatcc
      481 gtccgcggtg aaggactggc gctgacatta gccactgaat tgataaacct cgcctatgag
      541 cggcacagca cgcatctgtt tatttatacc aaaaccgaat acgaggcgct gttccgccag
      601 tgcggttttt ccacgctgac cagcgtaccc ggcgtgatgg tgctgatgga aaacagcgcc
      661 acgcgactga aacgctatgc cgaatcgctg aaaaaatttc gtcatccagg gaacaagatt
      721 ggctgcattg tgatgaacgc caatcccttt acgaatggtc accgttatct gattcaacag
      781 gctgcggcac agtgcgactg gttgcatctg tttttagtca aagaagattc ttcacgcttc
      841 ccctatgaag accggctgga tttggtgtta aaaggcaccg ccgatattcc acgcctgact
      901 gtgcatcgtg gctccgaata catcatctcc cgcgctacgt tcccttgcta cttcattaaa
      961 gaacagagcg tcattaacca ttgttacacc gaaattgatc tgaagatttt ccgtcagtac
     1021 ctcgctcccg cgctgggtgt aactcaccgc tttgtcggta ctgaaccctt ttgtcgcgtt
     1081 accgcccagt acaaccagga tatgcgctac tggctggaaa cgccgactat ctccgcaccg
     1141 cccatcgaac tggttgaaat tgagcggctg cgttaccagg agatgccgat atccgcttcc
     1201 cgggtacgtc aactgctggc gaaaaacgat ctcacggcta tcgcgccgct ggtccctgca
     1261 gtcacgctgc attatttgca gaacctgctt gagcactccc gccaggacgc ggcagctcgt
     1321 caaaagaccc ccgcatgaga aacaggtgaa aaatgaaaat aaaccagccc gccgttgcag
     1381 gcacccttga gtctggggat gtgatgatac gcatcgcccc actcgatacg caggatatcg
     1441 acctgcaaat caatagcagc gttgagaaac agtttggcga tgcaattcgc accaccattc
     1501 tggacgttct cgcccgctac aacgtgcgcg gcgtacagct gaatgtcgat gacaaaggcg
     1561 cactggactg cattttacgt gcacgactgg aagccctgct ggcacgcgcc agcggtatcc
     1621 cggctctgcc atgggaggat tgccaatgat ttccgcttcg ctgcaacaac gtaaaactcg
     1681 cacccgccgc agcatgttgt ttgtgcctgg tgccaatgcc gcgatggtca gcaactcctt
     1741 catctacccg gctgatgccc tgatgtttga cctcgaagac tccgtagcat tgcgtgaaaa
     1801 agacaccgcc cgccgcatgg tttaccacgc gctgcaacat ccgctgtatc gcgatattga
     1861 aaccattgtg cgtgtcaacg cgctggattc cgaatggggt gttaacgacc tggaagccgt
     1921 cgttcgcggt ggtgcggacg ttgtgcgtct gccgaaaacc gataccgctc aggatgttct
     1981 ggatattgaa aaagagatcc tgcgtatcga aaaagcctgt ggtcgtgaac ccggcagcac
     2041 cggcctgctg gcggcgattg aatctccgct ggggattacc cgcgcagtgg aaatcgctca
     2101 cgcttccgag cgtttgatcg gtatcgccct cggtgcagaa gactatgtgc gcaacctgcg
     2161 tacagaacgc tccccggaag gaactgaact gctgttcgca cgctgttcca ttttgcaggc
     2221 cgcgcgctct gcgggtattc aggcgttcga taccgtctat tccgacgcta acaacgaagc
     2281 cggatttctg caagaagccg cccacatcaa acagctgggc tttgacggca aatcgctgat
     2341 caacccgcgt cagattgatc tgctgcacaa cctctacgca ccgacccaga aagaagtgga
     2401 tcacgcccgc cgcgtcgtag aagccgctga agccgccgct cgcgaaggcc tcggcgtggt
     2461 ttccctgaac ggcaagatgg tggacggtcc ggttatcgat cgcgcccgtc tggtgctctc
     2521 ccgtgcagaa ctttccggca tccgcgaaga ataaggcaat caaaatgacg cagaaaattg
     2581 aacaatctca acgacaagaa cgggtagcgg cctggaatcg tcgcgctgaa tgcgatcttg
     2641 ccgctttcca gaactcgcca aagcaaacct accaggctga aaaagcgcgc gatcgcaaac
     2701 tgtgcgccaa cctggaagaa gcgattcgtc gctctggttt acaggacggc atgacggttt
     2761 ccttccatca cgctttccgt ggcggtgacc tgaccgtcaa tatggtgatg gacgtcatcg
     2821 cgaagatggg ctttaaaaac ctgaccctgg cgtccagctc cctgagtgat tgccatgcgc
     2881 cgctggtaga acacattcgc cagggcgtgg ttacccgcat ttatacctcc ggcctgcgtg
     2941 gtccactggc ggaagagatc tcccgtggtc tgctggcaga accggtgcag atccactctc
     3001 acggcggtcg tgtgcatctg gtacagagcg gcgaactgaa tatcgacgtg gctttcctcg
     3061 gcgtcccgtc ctgtgatgaa ttcggtaatg ccaacggcta caccggtaaa gcctgctgcg
     3121 gctccctcgg ctatgcaatg gttgatgccg acaacgcaaa acaggtcgtg atgcttaccg
     3181 aagaactgct gccttatccg cataatccgg caagcattga gcaagatcag gttgatttga
     3241 tcgtcaaagt tgaccgcgtt ggcgatgctg caaaaatcgg cgctggcgcg acccgtatga
     3301 ccactaaccc gcgcgaactg cttattgccc gtagcgctgc ggatgtgatt gtcaactctg
     3361 gctacttcaa agaaggtttc tccatgcaaa ccggcaccgg cggcgcatcg ctggcggtaa
     3421 cccgtttcct ggaagacaaa atgcgtagcc gcgatattcg cgccgacttc gcccttggcg
     3481 gtattaccgc gacgatggtt gacctgcacg aaaaaggtct gatccgcaaa ctgctggatg
     3541 tgcagagctt tgacagccat gctgcgcaat cgctggcccg taaccccaat cacatcgaaa
     3601 tcagcgccaa ccagtacgct aactggggtt cgaaaggcgc atcggttgat cgtctcgacg
     3661 tggtggtact gagcgcgctg gaaattgaca cccagttcaa cgttaacgtg ctgaccggct
     3721 ctgacggcgt actgcgtggt gcttccggtg gtcactgcga taccgcgatt gcctctgcgc
     3781 tttccatcat cgtcgcgccg ctggtacgcg gtcgtattcc gactctggtg gataacgtac
     3841 tgacctgcat caccccaggc tccagtgtcg atattctggt cacagaccac ggtatcgcag
     3901 ttaacccggc acgtccggaa ctggcagaac gtctgcagga agcgggcatt aaagtggttt
     3961 ccattgagtg gctgcgcgaa cgtgcgcgtc tgctgaccgg tgaaccacag ccgattgaat
     4021 tcacagaccg cgtcgttgcc gttgtgcgtt accgcgatgg ctcggtgatc gatgttgtgc
     4081 atcaggtgaa ggaataagcc atgcacctgc ttcctgaact cgccagccac catgcggtat
     4141 caattcccga gctgctcgtc agccgggatg aaaggcaagc acggcaacac gtctggctca
     4201 agcgccatcc tgttccactg gtctccttta ccgtggttgc gcctgggccg attaaagaca
     4261 gcgaggtcac acgccgaatt tttaatcatg gcgtgacagc cttgcgtgcc ttagccgcaa
     4321 aacagggctg gcaaattcag gagcaggctg cactggtttc cgccagcggg ccggagggca
     4381 tgttgagcat tgccgccccg gctcgcgacc tcaagctcgc caccattgag cttgaacata
     4441 gtcatcctct cgggcggtta tgggatatcg atgtcctgac gcccgaaggc gaaattctct
     4501 cccgccgcga ctattcactg ccgcctcgcc gctgcctgtt gtgcgagcaa agcgcagccg
     4561 tctgcgcgcg tggaaaaacc catcaactga ccgatttact caaccgcatg gaggcactgc
     4621 tgaacgatgt cgatgcctgc aacgtcaact aaaaccacaa agcttgcgac gtcattaatc
     4681 gatgagtacg ccctgctggg ctggcgcgcc atgctgactg aagtcaatct gtcaccgaaa
     4741 ccaggcctcg tggatcgcat taactgcggt gcgcacaaag atatggcgct ggaagatttc
     4801 caccgcagcg cgctggcgat tcagggctgg ctaccccgtt tcattgaatt tggtgcctgt
     4861 agtgcggaaa tggcaccaga agcggtactc cacggattac gcccaattgg tatggcttgc
     4921 gaaggtgata tgttccgcgc cactgcgggc gtaaacacgc ataaaggcag cattttttct
     4981 ttagggctgc tatgtgcggc aattggccgt ttgcttcaac tcaaccaacc ggtaacgcca
     5041 acaaccgttt gttctacggc ggcaagtttc tgccgtggcc tgaccgatcg cgaactgcgt
     5101 accaataatt cacaactgac ggcaggtcaa cggttgtacc aacagcttgg ccttaccggc
     5161 gcacgcggtg aagccgaagc gggttatcca ctggtgatca atcacgcctt gccgcattac
     5221 ctcactctgc tggatcaggg gttagatcct gaactggcat tgctcgatac cttgctccta
     5281 ctgatggcga tcaacggcga taccaacgtt gcatcgcgcg gtggcgaggg gggcctgcgc
     5341 tggctacagc gcgaggcgca aacattattg caaaaagggg gcattcgaac ccccgccgat
     5401 ctcgattatc tccggcagtt cgacagggag tgtatcgaac gaaatctcag tccaggcggc
     5461 agtgctgacc tactgatcct tacctggttt ttagcacaga tttaattatt taagcacttg
     5521 ataaatttgg aaatattaat tttcggagaa cccgtatgtc tttagcaaaa gataatatat
     5581 ggaaactatt ggccccactg gtggtgatgg gtgtcatgtt tcttatccct gtccccgacg
     5641 gtatgccgcc gcaggcatgg cattacttcg ctgtgtttgt ggcaatgatt gtcggcatga
     5701 tcctcgagcc aattccggca acagcgatca gttttattgc ggttactatt tgcgttattg
     5761 gcagtaatta cctgctcttt gatgccaaag aattagctga cccagcgttt aatgcgcaaa
     5821 aacaggcgct gaaatggggc ctggctggtt tttccagcac cacggtatgg ctggtatttg
     5881 gcgcatttat ttttgcatta gggtatgaag tttccgggtt aggtcgtcgc attgcccttt
     5941 tcctggtgaa attcatgggc aaacgcacgc tgacgttggg ttatgcgatt gtcattatcg
     6001 acattctgct ggcaccgttt acaccttcca acaccgcgcg taccgggggt acggtttttc
     6061 cggtcattaa aaacctgccg ccgttgttta aatcattccc gaacgatccg tccgcgcgtc
     6121 gtattggcgg ctatttgatg tggatgatgg tcattagtac cagtctgagt tcgtccatgt
     6181 ttgtcaccgg tgcggcacca aacgtgctgg gtctggagtt cgtcagcaaa attgccggta
     6241 tccagattag ctggttgcag tggttcctct gcttcctgcc ggttggggtt atcttgctta
     6301 tcattgcgcc gtggctttcc tacgtgctgt acaaaccgga aatcacacac agtgaagaag
     6361 tggcaacctg ggcgggtgat gaactgaaaa ccatgggtgc gctgacacgc agagagtgga
     6421 cactgattgg ccttgtattg ctcagcttag gtttgtgggt atttggcagt gaagtcatta
     6481 atgctactgc ggttggtctg ctggcagttt cgctaatgct ggccctgcac gttgtgcctt
     6541 ggaaagacat tacccgctat aacagcgcat ggaacacact ggtcaacctg gcaactctgg
     6601 ttgtgatggc taacggcctg actcgttctg gttttattga ctggttcgcc ggtaccatga
     6661 gtacgcacct ggaaggattc tcaccaaacg caacggtgat tgtactggtt ctggtgttct
     6721 actttgcaca ctacctgttt gccagcctgt ctgcgcacac cgcaaccatg ctgccggtta
     6781 ttctggccgt cggtaaaggt attccgggcg taccaatgga acaactgtgt atcctgctgg
     6841 tgctgtctat cggtatcatg ggctgtctga cgccgtatgc aaccggtcca ggggtgatta
     6901 tttacggctg tggctatgtg aaatcaaaag attactggcg tcttggcgca atcttcgggg
     6961 tgatttacat ctctatgttg ctgttggttg gctggccgat tctcgccatg tggaactaat
     7021 acgttcgcca aacgctgaat aaatcatcac gcccgccagg taagcccacc tggcgggctt
     7081 ttttatgatt taatagatag tattcagtgt atgtatgagt tccacactca ttatgaaagc
     7141 attctggcgt aacgccgcgt tgctcgcggt ttctctgctt cccttctctt ctgccaacgc
     7201 cttagcgttg caggcaaaac agtatggcga ttttgatcgc tatgtcctgg ccctctcctg
     7261 gcaaaccgga ttttgccaga gtcaacacga tcgaaatcgt aacgaacgag atgaatgtcg
     7321 cctgcaaacc gaaacgacca acaaagctga ttttctgacc gtacatggtc tgtggccagg
     7381 attgcctaaa tcggttgctg cccgtggtgt tgatgaacgc cgctggatgc gcttcggttg
     7441 cgctactcgc ccaatcccga atctaccaga agcgcgcgcc agccgaatgt gttcatcgcc
     7501 ggaaaccgga ttatcactgg aaacggccgc taaactaagt gaagtcatgc caggagctgg
     7561 cggacgttcc tgcctggaac gctacgaata tgccaaacac ggtgcctgct ttggttttga
     7621 tccggacgca tacttcggta cgatggtacg cctgaatcaa gaaattaaag agagcgaagc
     7681 cggaaaattc cttgcggata attacggtaa aacagtgagc cgccgtgact ttgacgccgc
     7741 ctttgccaaa agctggggaa aagagaacgt gaaagcagtt aagctaacgt gccagggtaa
     7801 ccctgcgtat ttgactgaaa ttcagatctc gatcaaagct gacgccatca acgctccgct
     7861 ttctgcaaac tcattcttgc cacaacctca cccaggtaac tgtggcaaaa cctttgtgat
     7921 tgataaagcg ggttattaat catctgattt acaaaacacg ctaattcgtc ttccataaac
     7981 caaggcgatt aagatttata cataatgcgc tgcattgagg aattccctga atgtgacgca
     8041 aatcacttca aagagtgagc aacagtcagt atcatcatgt gagttaaacc ctcgccgcct
     8101 gacggtgagg gttttctttt gggtatgttt atctgcgaca ctcgcagcac cgacgacatg
     8161 gagtaaaaat gtccagacca actatcatca ttaacgacct ggatgccgaa cgcatcgata
     8221 ttctgctgga gcaacccgcc tatgctggtt tgccaatcgc cgacgcgtta aacgcagagt
     8281 tggatcgcgc ccaaatgtgt tcgccagaag agatgccaca cgacgtggtg acaatgaaca
     8341 gccgggttaa attccgcaat cttagcgatg gcgaagtgcg tgtgcgcacg ctggtgtatc
     8401 cggcaaaaat gaccgatagc aatactcagc tttccgttat ggctccggta ggtgccgcac
     8461 tgctggggct gcgcgttggc gattccattc actgggaact tccgggcggc gttgcaaccc
     8521 accttgaagt gctggaactc gaataccagc cagaagctgc tggcgactac ctgctttaat
     8581 cccatctgca caagcgataa ctcgctttgc ccagaggatg cactcgcatc ctctttacgc
     8641 aaaatcagca atttttcctg gttctcactg ttcacttttg ctgcaaaatt attccgtttc
     8701 gtttgtggga ataaccatgg cagaagcatt ttacatcctg ataggatttc tgattatggc
     8761 ggcgattatc gtcatggctg tcctttacct cgaaaaccac tcctgacgat catattgttc
     8821 cccccggcat cgcattcacc agacctgaaa ccgccttctg cgccgcctct gcgctttgtg
     8881 caccgggtac cagaatcacc ttacggcact cctcttcacg tttttcgaaa atctcatatc
     8941 cccgggcggc ctcttcaaac ggcatatagt gggtaacaat ttcttctggt ttcagtaatc
     9001 ctttctcaat taacggtaat aattctccca gccatgcgtg aacgtgggtc tgtcccattt
     9061 taaacgacaa ccctttatca aaggcgtcgc caaacaggaa accgtgaata aatccagcgt
     9121 agacgcccgg tacgctaaca atgccgccac gcctgaccgc cgcaatacac tgacgcaacg
     9181 ctttaccgct gctgccctcc agtttcaggt tagtcagcac cgtttccgtg gtgctgcctt
     9241 tcgcttcaaa accgacggcg tctattactg catccacgcc ccggtgacct gccgtttgtt
     9301 caataattga ctgtgccgga tcgctgtctt catcaaaatt aatcgggatc gcgccgtagc
     9361 ggtcggcggc gaaatgcaag cggtagggat gatgatcaac aacaaaaatc tgttccgcac
     9421 cgagcaaccg tgcacaggcg attgtcaaca atcccacagg accagcacca tagactgcaa
     9481 cgcttgaacc ttgttggatc tgcgcatttt ttgctgcctg ccatgccgtt ggcagaatat
     9541 cagaaaggaa aagcgcttta tcatctgaaa gcaaaggcgg tactttaaac ggccccacat
     9601 tccctttagg gacgcggaca tattccgcct gcccaccagg aacgccgcca tacaggtgac
     9661 tataaccaaa caatgccgct ggagctggta tctgtttttt attgagcgca gcgcctttac
     9721 ccgcattggt attttcgcag gcggcatatt gttgcaatcg acagaaaaaa cagtcgccac
     9781 aagcaatgac gaacggaatt accactcggt cgcctttttg caaatttttt acgtcctttc
     9841 cggtttcaac tacttccccc ataaattcat gaccaaaaat atcgccatgt ttaacctgag
     9901 gtattttgcc tcgataaaga tggaggtcag agccacagat cgccgttgcc gtaatacgca
     9961 gaataatatc atctgcctgt tcaacgcccg gatcgggaac attttctacc tgaacgtgat
    10021 gtgggccgtg ataagtcaat gctttcatgc aacctccaga gacagttcaa ataagagtca
    10081 gtctttaagg gtagctatca cagcgggaaa acgggcggta ccacaggttt tgggagaatt
    10141 cctggtgttc agtgagaata tattcatcac agaaacagtt cgtaaggaaa aagaaccaga
    10201 caaatatcag ggataaatat tataatcatg gcgaatgatt tgttcatgat taacagggag
    10261 aaagggttat gtataagaca atcattatgc cagttgatgt atttgaaatg gaattgagcg
    10321 acaaagctgt tcgccacgct gaattcctcg cccaggatga cggagttatt catctacttc
    10381 acgtactacc cgggtcagcc agcctgagcc tgcaccgttt tgccgctgat gtgcgtcgtt
    10441 ttgaagagca tctgcaacat gaagcacaag aacgtctgca aacgatggtc agccacttca
    10501 ccatcgatcc ttcccgcatt aaacaacatg tccgttttgg tagcgtgcgg gatgaagtca
    10561 atgagttggc agaagaactg ggggctgatg ttgtagttat tggttctcgc aacccatcga
    10621 tttcgaccca tctgttaggt tctaacgcct cgagcgtgat ccgccacgcc aatctgccgg
    10681 tgctggttgt gcgttaattg ccagaataag tatcccgccc tgcccggagc catcccggcg
    10741 gggcttttta atgccataaa aaagccgcca ggtttgaccc cggcggctaa gcaattgcag
    10801 gtgaatctta cttcttctta tgcagttttg gtgcgaatca ggtagtcaaa agcactcaga
    10861 gaggctttgg caccttcgcc agtggcgatg atgatctgct tgtacggaac cgtcgtacag
    10921 tcacccgctg cgaacacgcc tttcacgttg gtttcgcatt tcgcatcaat gataatctcg
    10981 cccatgcggt tacgttcgac tgcgccttcg agccagttgg tgttcggcag cagaccaatc
    11041 tggacgaaaa taccggccag ttcgatgttg tgaatatcgc cgctgacacg atctcgatat
    11101 tccagaccaa cgactttgct gccgtcgcct ttcacttccg tggtttgcgc attcagaata
    11161 atgtcgacgt ttttcaggct gcgcagtttg tcctgcagaa cctggtcggc tttcatttct
    11221 ggcgcaaatt ccagcagcgt tacgtgctca acgatacccg ccaggtcaat tgccgcttcc
    11281 acgccggagt taccgccgcc gataaccgct acgcgtttac ctttaaacag cgggccgtcg
    11341 cagtgcgggc agtaggtcac gcctttggtg cgatactgat cttcgcccgg aacgttcatg
    11401 ttgcgccatt ttgcaccggt cgccacgata atgctgcgtg ctttcagtac cgcgccagaa
    11461 gctgtttcaa tctgatgcag accaccttca actgctgctg ggatcagttt gctggcgctc
    11521 tggctgtcga tcacatcaac gtcgtattca tcaacgtgaa ctttcagtgc gcctgccagc
    11581 ttctgccctt cagtcttcgg tacagaaatg tagttttcga tatcaacggt atcgaggatc
    11641 tgaccaccaa aacgttcgcc catcagaccg gtacggatgc ctttacgtgc ggagtaaatt
    11701 gctgccgctg cacccgccgg gccggaaccg acgattaata cgtcataagc atcacgcttg
    11761 ttcagctctt ctgccgcacg tttttccgcg ccagtatcaa ttttggcaac gatttcagtc
    11821 aacgtcatgc ggccctgacc aaactctttc ccgtttacga acactgccgg aacgcccatc
    11881 acgttgcgat cggtgatttc gttctggaag gtgccgccgt caattgcagt gtgcttgatg
    11941 cgcgggttca gtacgctcat caggttcagc gcctgcacca cgtccgggca gttgtggcaa
    12001 gagagcgagt aataggtttc gaattcaaaa tcaccgtcaa tatggcgaat ctgctccagc
    12061 agagactgcg cttctttcga cggatgacca ccggtccaca gcaacgccag taccagcgag
    12121 gtgaactcgt ggcccagcgg ggagcctgca aaacgtggcc cctggttgga acctgggttg
    12181 gtgatcagga aagacggctt acgcaccggc aagctgttat cttctttaaa ggtgactttg
    12241 tctgacagtt ctgcgatttc agccaacagt tccttgattt ctgccgattt agcgctgtca
    12301 tccagcgtgg caattaactc aacaggcttg gtcaatttct caaggtaagc cttgagttga
    12361 gttttcatat ttgtgtcgag catgtttatc tcctgggctt taaacatcat catgcaagcg
    12421 gcctctgcgg ctacctggat gcagcttgca tcatggtgcg gggaagaaaa tcgggtgccg
    12481 cagcacccga agaattaggt gaatttccga agtatttcgc gtcagagcaa ggcggctagc
    12541 ctgtgaatcc ccgggagctt acacaagtaa gtgaccgggg tgagcgggcg acgccaacgc
    12601 cgctatggcg tgaaagacga aggaaattta gattttacca accaggtcca gagacggagc
    12661 cagagttgct tcaccttctt tccatttagc cgggcaaact tcacctgggt gagaagctac
    12721 gtactgtgct gctttgattt tacgcagcag gtcagacgcg tcacggccaa tgccttcagc
    12781 ggtaacttcg attgcctgga tgataccctg cgggtcaaca acgaaggtcg cacggtcagc
    12841 cagaccttca tcttcacgca tgttgtcgaa gttacgggtc agggcgccag tcgggtcgcc
    12901 gatcatcgca tatttgattt tagcgatggt ttcagagctg ctgtgccatg ctttgtgggt
    12961 gaagtgagta tcggtagata ctgcgtatac gtctacgccc agtttctgca gttcttcgta
    13021 gtggtcagca acgtcaccca gttcggtcgg gcatacgaaa gtaaagtcag ccgggtagaa
    13081 gaagaagacg ctccagcggc cttcggtatc tttttcggtg atttcgatga attcgccgtt
    13141 tttgaatgcc tggtttttaa aaggtttaat tttggtgtta atcaaggaca tctatacttc
    13201 ctccgtgttt tcgatgagat gtaaggtaac caatttttgc cgattcggct aatgcgtttc
    13261 cattatcaaa tcgataagtt ttaccttaca accttcgtaa gacaactttg tgaactttgc
    13321 accgccagcg gcgataaaaa gtaaaatggc cccctttcca ggtgaccgtg taatctgaac
    13381 taccctttgg tatcttcagt gcctgcctgc aggctgaggt gttgccctta caaatgcaac
    13441 aacgacatgg attacaacac cctcataaac aaagggcaat cacctgatct aagctcttac
    13501 ctatgacagt gataggttat gccttttact cgacttttgc actgactgaa aaggacaaat
    13561 taatgttaaa aaagatactt ttactggctc tgcttcctgc aatcgccttc gcagaggaac
    13621 ttcctgctcc agtaaaagcg attgaaaaac agggcattac aatcatcaaa acattcgatg
    13681 cccccggagg aatgaaaggt tatctcggaa agtatcagga tatgggcgtc accatctacc
    13741 tgactccaga tggtaagcac gctatctctg gttacatgta caacgagaaa ggtgaaaacc
    13801 tgagtaacac acttatcgaa aaagaaattt acgcaccagc cggacgcgaa atgtggcaac
    13861 ggatggaaca atcccactgg ctcctcgacg gtaaaaaaga tgcgccggtc attgtctacg
    13921 tcttcgccga tccgttctgc ccatattgta aacagttctg gcagcaggcg cgcccgtggg
    13981 tagattctgg caaagtgcaa ttaagaacat tgttggttgg ggttatcaag ccagaaagcc
    14041 cggcgacagc agcggcaatt cttgcctcca aagatcccgc aaaaacctgg caacaatatg
    14101 aagcctctgg tggcaagctt aagctaaacg tgcctgcaaa cgtaagtaca gagcaaatga
    14161 aagtgttaag tgacaatgag aaactgatgg acgatctggg ggcaaatgtc acgccggcta
    14221 tctattacat gagtaaggaa aatacgctac aacaggccgt ggggttgccc gatcagaaaa
    14281 cgcttaatat cattatgggg aataaataaa aggtaattca tggatggttg aactatatcc
    14341 ctgcttttca accatcctaa aaaagcatga attgctcgct ctgccctaag tggctgtgct
    14401 attttagaaa aacttaatcc tgagttaagc aaaaaaacat aatcaataaa aatatatacg
    14461 caaaaaacat tgattaagtg aatatatcat ggaagaaaaa tataaccgga gtagtgtatg
    14521 gccaatctct acgacttgaa aaagttcgac ttaaatcttc ttgtcatatt tgagtgtatt
    14581 taccagcatt taagcattag caaagctgct gaatcactat atatcacccc atcagccgtg
    14641 agccagtcgt tacaacgctt acgtgcgcaa tttaatgacc ctttattcat tcgctcagga
    14701 aaaggtatcg cgccgacgac aacagggtta aatctgcatc accatcttga gaaaaatctc
    14761 agaggccttg aacaaacaat taatatagtc aataagtccg aactaaagaa aaactttatt
    14821 atctacggcc ctcagctcat ttcttgctct aataatagta tgctgatccg ctgcctacgg
    14881 caagattcct ctgtcgagat tgagtgccat gatatcctca tgtcagcaga gaatgctgaa
    14941 gaactgttgg ttcaccgcaa agccgatctg gtgatcaccc aaatgccagt gatcagccgt
    15001 tccgtcattt gcatgccatt gcatacgatt cgcaatactc taatttgtag taataggcat
    15061 ccacgaatta ctgacaatag cacttatgaa caaattatgg cagaagagtt cacccaatta
    15121 atatctaaat cagcaggggt tgatgatatt caaatggaaa tagacgagag atttatgaat
    15181 cgcaaaatct catttcgtgg tttctctttg ctgacaatca ttaatagcat tgcagttaca
    15241 gatttactgg gaatagtccc ctatgaactt tataattcct accgtgactt tcttaactta
    15301 aaagagataa aactagaaca tccgttacct tcaataaagc tttacatttc ctataataaa
    15361 tcttctttaa ataatttggt gttctcccga tttattgacc gtctaaatga gagtttttga
    15421 tatataacta cagacagcta ctataacttt catctattta ttcacagcgc gaatgaaaaa
    15481 taaaacactc tgctttacag tgtttacttt ataattaaca gacttatctc actgatcacc
    15541 ctgtaacgtt cagagagcgt cttcagatgt ctatttataa aattcctctt ccgctcaata
    15601 ttctggaagc tgcacgagag cgtattacct ggacactcaa caccctaccc cgcgtttgtg
    15661 tctcattttc tggcggcaaa gactctggtt taatgctgca tctgacagcc gaacttgccc
    15721 gacaaatggg caaaaaaatc tgcgttttgt ttatcgactg ggaggcgcaa ttctcttgca
    15781 ccattaacta tgttcagtcc ctgcgcgagt tgtacaccga tgtcatcgaa gagttttact
    15841 gggttgcgct cccgcttacg acgcaaaatt ccctttcaca ataccaaccc gaatggcagt
    15901 gctgggaacc tgatgtcgaa tgggtacgtc aacctcccca agatgcgata accgaccctg
    15961 actttttctc cttttaccag ccaggcatga ccttcgaaca atttgtacgt gagtttgccg
    16021 aatggttttc acaaaaacgt ccggcggcga tgatgatcgg catccgtgcg gatgagtcct
    16081 acaaccgttt tgtcgccatc gccagtttaa ataaacaacg ttttgccgac gataaaccct
    16141 ggactacggc cgcaccaggc ggtcatagct ggtacattta ccccatttac gactggaaag
    16201 tggctgatat ctggacctgg tatgcaaatc atcaaagtct ctgcaaccca ctgtataacc
    16261 taatgtatca ggcaggcgtt cctctgcgtc atatgcgaat ttgcgaacct tttggcccgg
    16321 agcaacgaca aggattatgg ctctatcacg ttatcgaacc ggatcgctgg gctgctatgt
    16381 gcgcacgagt cagcggggta aaaagtggcg gcatttacgc cggacatgac aatcatttct
    16441 atgggcatcg gaaaatcctc aagccagaac atttagactg gcaagaatat gcattattgc
    16501 tgctcaatag catgccggaa aaaacagctg agcattaccg caataaaatc gccatttatt
    16561 tgcactggta tcagaaaaaa ggcatcgagg ttccacaaac ccagcaaggg gacattggcg
    16621 cgaaagatat cccctcctgg cggcggatat gcaaagtttt actcaataac gattactggt
    16681 gtcgggcatt atcatttagc cccacaaaat cgaagaacta tcagcgttat aacgaacgga
    16741 taaaaggaaa acgtcaggaa tgggggatac tatgcaacaa cgattaacgc aggatttaac
    16801 gcaatttctc gccagcttgc cggaagatga tcgcatcaaa gcgattaatg aaatccgcat
    16861 ggcgatccat caggttagcc cctttcgtga agagccagtg gattgcgttc tgtgggttaa
    16921 aaacagccaa cttatgccta atgattacaa cccaaacaac gtggcaccac ccgaaaaaaa
    16981 actgctgcaa aaatccattg aaatagatgg ttttacccaa cccattgtgg tcacacatac
    17041 ggataaaaat gccatggaaa tcgtggatgg ttttcaccgc catgaaattg gtaaaggctc
    17101 atcatcatta aaattacgct taaaaggtta tttgccggtg acctgtctgg aaggtacgcg
    17161 taatcaacgc atcgccgcga ctattcgtca taatcgcgct cgtggacgcc atcaaatcac
    17221 cgccatgtcg gaaatcgtcc gtgaacttag ccagttggga tgggacgata ataaaattgg
    17281 caaagagctg ggaatggaca gcgacgaagt gctgcgcctg aagcaaatta acggcctgca
    17341 agagttgttt gccgaccgtc aatattcccg cgcctggacg gttaaatagc taaagctggc
    17401 gcaggcgttc agctgctgcc agcaacgtcg attccttctt ggcaaaacag agacgaatca
    17461 gtttatgtgg gaagggatcg gcgcaaaaca ccgacagcgg aatcgccgct acgccgtgct
    17521 cctgcgtcag ccactggcaa aactcaacat catccagggt agaaaccgcg ctgtaatcca
    17581 ccagcaaaaa gtatgtacct tcacacggta aaatctccag ccggctttca tttaaagcat
    17641 tcaccagaat atcgcgcttc tggcgataaa agtccggtaa cgcaagataa tgctcaggtt
    17701 ctgcacgtag catatcagca agcgccagct gtgccggggt attcaccgaa aaggtcagat
    17761 actgatgtac cttgcgaatt tcggcgctga tgggcgctgg cgcaacacaa taacccactt
    17821 tccagccggt catatgatag gtcttgccaa atgaagaaac cgccactgcc cgctcacgca
    17881 gctgcggatg cgccagcaca ctggcatggc cctgttgtga aaagttgatg tgctcgtaga
    17941 cttcatcgct aatgacaaaa atctcgtgcc cggcgatcgc ctgccacaaa gcggcgaaat
    18001 cagcctgctg ccagacagtt gcactggggt tatgcggagt gttgaggatc accagtctgg
    18061 tgcgctcgct taataatgcg gcaaattcct gccagtcaac gcgaaaatgc ggtggttgca
    18121 gtgccatacg cttcactatt cccccagaaa gcgcgatggc gggggcgtaa ctgtcatagc
    18181 tgggatcaaa acaaatcact tcatcgccat tgcgcaccag tgcggtaatc gccgcgtata
    18241 acgcttccgt cgcccctgcc gttacggtga tatcgctatc ggcatctggt tgatagccat
    18301 acaaacgttc cgttttctga gcaatcgcct cgcgcaaggc ctgcacgccg gtcatgggcg
    18361 cgtattggtt tgccccctgt gcaacgtggt gcgccagccg ctcctgtaaa tagcgcggac
    18421 catcaaaatc aggaaagcct tgcgacaggt taatcgcctg gtgttgctgc gccagcgcgc
    18481 tcatctgggt gaaaatagtg gtgccaagtt gtggaagttt gctttgtgga atcagagggt
    18541 tatttgtcat ttttattgta cctgacgaag ttgcgtgttg aaggcactat aacacgatgc
    18601 tagtatttgg caatcaagac gtttagatgt ctaaataaaa caataaggac aacacaacat
    18661 gcctcacaat cctatccgcg tggtcgtcgg cccggctaac tacttttcac atccaggaag
    18721 tttcaatcac ctgcacgatt ttttcactga tgaacaactt tctcgcgcgg tgtggatcta
    18781 cggcaaacgc gccattgctg cggcgcaaac caaacttccg ccagcgtttg gactgccagg
    18841 ggcaaagcat attttgtttc gcggtcattg cagcgaaagc gatgtacaac aactggcggc
    18901 tgagtccggt gacgaccgca gcgtggtgat tggcgtcggt ggcggtgcac tgctcgacac
    18961 cgcgaaagcc ctcgcccgcc gtctcggtct gccgtttgtt gccgttccga cgatcgccgc
    19021 cacctgcgcc gcctggacac cgctctccgt ctggtataat gatgccggac aggcgctgca
    19081 ttatgagatt ttcgacgacg ccaattttat ggtgctggtg gaaccggaga ttatcctcaa
    19141 tgcaccgcaa caatatctgc tggcggggat cggtgacacg ctggcgaaat ggtatgaagc
    19201 ggtggtgctg gctccgcaac cagaaacgtt gccgctaacc gtgcgactgg ggatcaataa
    19261 tgcgcaagcc attcgcgacg tcttgttaaa cagtagcgaa caggcgctga gcgatcagca
    19321 aaatcaacag ttaacgcaat cattttgcga tgtggtggat gctattattg ctggtggtgg
    19381 gatggttggt ggtctgggcg atcgttttac gcgtgtggcg gcagctcatg ccgtgcataa
    19441 cggtctgacc gtgctgccgc aaaccgagaa gtttctccac ggcaccaaag tcgcctacgg
    19501 aattctggtg caaagcgcct tgctgggtca ggatgatgtg ctggcgcaat taactggagc
    19561 gtatcagcgt tttcatctgc cgactacact ggcggagctg gaagtggata tcaataatca
    19621 ggcggagatc gacaaagtga ttgcccacac cctgcgtccg gtggagtcca ttcattacct
    19681 gccagtcacg ctgacaccag atacgttgcg tgcagcgttc aaaaaagtgg aatcgtttaa
    19741 agcctgacgt acaaatttag cagcagcgcg cgccgccttt tccaccgtag cgcgcgtcct
    19801 gccgctcacg gaaaaactct tcgtaggtca tcggcgtttg atcgggatgg ttaacccgca
    19861 tatgttcgac atagttgtcg taatcaggca taccaatcat cagcttcgcc gcctgaccta
    19921 aatattttcc ggcttttgcc agtgaatcaa acatcttggc ctccgctaac catgttgctg
    19981 aaagagtgcc ggatgcggcg tgaacgcctt atccggccta caaatgctat caacgcgctc
    20041 ggtcagtccc ctcgccccac cggggagagg gttagggtga gagggaaccc tgggcactaa
    20101 gccaacattc gccaacatcc ccccctcact ctgactttag tgtgcgcctt ttgcctgcgc
    20161 cacgatctcc tcgacatttt ccggcattgg ttcatacggc gtttctttcg ccgttggctt
    20221 cggatctttc aatgccgcaa gtgccgtctt aatcgagaac agtgccagaa ccaccacgac
    20281 caccataaag aagatggtta acccggcatc cagacggttg ttgaacacca gttgcgccag
    20341 ctgtgactca gtatactgcg acggaatatt gccgctgtcg atcattgcct ggaacttatt
    20401 agcaatggcc aggaagccga ctttcgcatc cgggctaaac gctttctgcc agcctgcggt
    20461 cagggtacaa atcagcagcc aggccgttgg taccagcgcc acccaggcgt aacgttgacg
    20521 tttcatcttg aacaacacca cggcacagag catcagcgcc atccctgcca gcatctggtt
    20581 ggcaatacca aacagcggcc acagagtgtt aatgccgccc agcggatcga ccacgccctg
    20641 atggaggaag tagccccacg ccagtacgca cagcgctgtt gccagcaggt tagcaggcag
    20701 tgaatcggtc cgcttcaggc caggagacac cacgcccagc agatcctgca acataaagcg
    20761 cgcagcacgc gtacctgcat ccaccgccgt cagaataaac agtgcttcaa acaaaatggc
    20821 gaagtgatac cagaacgcca catccatcat gccgcccagc gcgccgtgca gaatgtaggc
    20881 catccccacc gccagcgtcg gcgcaccgcc cgcacgggaa atgatcgact gttcacccac
    20941 ttcgctggca atctggttta gcgtatctgg tgtaatgcta aagccccagc tactcaccac
    21001 ctgcgcggca gaagcgacca catccgccgt ccctgccgga gccagcaccg ccatcgggct
    21061 gttcatggca aaatacacgc ccggatcgat gatacaggcg gaaaccagcg ccataatcgc
    21121 cacgaaggat tccattaaca tcccaccgta gccgataaag cacgcctgcc cttcgttcgc
    21181 cagcatcttc ggcgtggtcc cagaagagat cagcgcatgg aagccagaca ccgcgccaca
    21241 ggcgatggtg ataaacagga acgggaacag gttaccggtc cataccgggc cagtgccatc
    21301 gacaaatttg gtcagcgcag gcatggtcag cgtcgggcgc ataatcaaaa tgcctaccgc
    21361 cagaccgacg atagtcccga ttttcaggaa ggtagagagg tagtcacgcg gggccagcag
    21421 taaccacacc ggcagcaccg ccgccacaaa accgtaaccc accagcatcc aggtcaactg
    21481 cacgccggta aagtcaaagt acggtgccca ggtcggactt tctgccaccc agccgccaga
    21541 gataatggcg aaaatcagga ataccagacc gatgaccgac acttcgccaa tacgccccgg
    21601 acgcagatag cgcaggtaga tccccataaa cagcgccagc ggaatggtga acgcaacggt
    21661 atatgttccc cacgggctat gagtcagggc tttcaccacg atcatcgcca gcactgcaag
    21721 gataatgacc atgatcataa agcaggccac cagcgcaatc accccggcgg ttggccccat
    21781 ctcttctttg accagctcac ccagcgagcg accgtcacgg cgcgtagaaa caaacagcac
    21841 catgaaatcc tgcaccgcac cggcgagaac caccccagcg agcagccaga tcatccccgg
    21901 caggtagccc atttgcgccg ccagtaccgg ccccaccagc ggacctgctc cggcaatggc
    21961 cgcaaaatgg tgaccgaaca gcactttctt gtccgtcggc acatagtcca gcccgtcgtt
    22021 atggcgcacc gctggcgtca tacgcgtcgg gtcaaccgcc agcacatttt tggcgatata
    22081 cagcccataa aaacggtaag cgatcagata gatacagacc gacgccacca caatccacag
    22141 cgcgttgatc tgttccccac gatttaaagc aatgtatccc agagcaaatg ctcccattac
    22201 agagagcact gtccagacga ggtatttccc tgatttgttc atagttgtta tccgtgtgcg
    22261 tgtccataga gatgttacat tttgtttcta taacatcttt gtacaattta acaacacagc
    22321 aaccatgtaa atcggagttg aaaccaatat ttaacttaac aatgttaact cgatcactcc
    22381 gttaaccgaa ttttcctgca atctcatcta attctgtcgg gttcatccca aaactgccgt
    22441 acccagccga caagtgcagc aacgccgccc ctgttcatcg aaaacgacga tttcccagct
    22501 ctgattttgc cgaccaagat gcagcggctg gcagacgccg cgtacctttc cctcagacac
    22561 cgggcgatgg tgtgttgcat taagttctgt gcctaccaca cactgtccgt cgcgggtcat
    22621 cataaatccg gccatcgatc ccagcgtttc cgccagcgcc gccgacgcgc cgccatgtag
    22681 taaaccgaac ggctgatgag tacgggtatc aaccggcatt tcggcttcca gcacatcatc
    22741 gcccagacgg gtatacacaa ttcccagatg cgccaccatt gtgttatcgc tggtggcgtt
    22801 cagttcgtcg agcgttaaat ggcgtttcca gatcatgctt atgcccccag cgttgagccg
    22861 ccatcgacca caatatcctg tagggtaata tggctggcga ggtcagaggc gaggaacaaa
    22921 atcgtgttgg cgatctcttg tggacgggcg attttcccca gcggaatgcc gagtttaaac
    22981 tgctcgccaa agccgcgaat acgctgttct tcggcgtcat cgctcaccca cagcgtgcgt
    23041 tgcatatcgg tgtcggtgga gccaggcgaa accacattac agcgcacgcc gctacccgcc
    23101 agttccagcc cgacgctcaa cgccaggctt ttcagcgccg ctttcgatgc gccataagca
    23161 ctcatgccaa tacgcggcgt gtgcgcggcg tcggacgcca cagtgacaat cgccccgccc
    23221 cgctgacggc gaaactggtt catggtttgc tggaacaggt taaacgcacc gccgacgtta
    23281 accgcaaaag tctgctgcca gtcctcttta ctgagctgat cggtcgcgcc catgcgtaaa
    23341 attcccgccg cattgaccag cgcgtccagt cgctccgttt cagctaacag tcgctgacac
    23401 acttgcgcga cctgcgcagc gtcggcaaca tccatcactt cggtcgcaaa gggatattgc
    23461 tcctgagtga acgcttgatc aaaacctgta actttcgctc ccgcctcaac aaacgccagc
    23521 gccgtggcgt agccgatacc tttacctgcg ccggttaccc agacattttt accgctgaaa
    23581 tccattattt cacctcgcgg gagagtagct tccaccaggc gtcgatggtc gggtttttcg
    23641 ccagcatgac aaagtcgata tcaccatgca ctttgcgcca gcgcgccgcc agcgccatca
    23701 tgcgcaccga atccagaccg tagtcgatca ggttgtcgtc atcgaacggt tcatcggact
    23761 cgtccagcaa cggcaggatc acctcacgca gcgccgcttt gctggcgggg ataggtgctg
    23821 gcagtaattc ttcagtcatc accacccggc cagaacgtcc ggccacatat ttcagcgaca
    23881 tcaaatgctc gtcacggctt aaatcggcca gcgcatccgc caccataaac ggtttaatat
    23941 cgcgcataaa tgcgtcggtt gcggtggtca tacagccaat gtgggcatat accccggtaa
    24001 taatcagctg gttacgtcca ctctctttca gcatttgctc cagcggagaa cgatgaaacg
    24061 cgctgtagcg ccacttcacc agcaccgtgt cgtcggcatc tggcgtcagg cgatccacca
    24121 ccttttgctg ttccggcgag cgggtcaggc ccggccccca catatcattc aacagcgccc
    24181 gatcttcatc gctctgctct ttcggctggg cggtgtaata aaccgggata ttgtgctgtt
    24241 tgcagtagtc gcgcagcgca gcaatattcg cgatcacctg ctccatcatc gggcagttct
    24301 cgccccagaa gctgacaaaa tagtcctgca tatcatggat taacaacgcg gcacgttgcg
    24361 gttcaaaggc ccagtcaact ttattctgcg gaatatcgtg agactccggc agtgcgtaag
    24421 cctgtaattt tggaatagcc atcgtgttct ctccttcagg ctgatgcgcg tgacgccagc
    24481 cactgacgta attgtttttt atcgactttc ccgaccgccg tcagcggaag tgaatccaca
    24541 cactccacgc gatccggtaa tttaaattcg gcaataccct gttcacgcag gaaacgacgc
    24601 acctgcaccg cgcgcagcgg ctcttttacc accagataag cgcagctttt ttcgcccatc
    24661 agctcatctt ccatgctcac cagtgcggcg tagatcaccg ccgggtggcg cagcagcagg
    24721 ttttcgatct cttcggcagc gatcttctcg ccgccacggt taatctgatc tttctcgcgc
    24781 ccctgcacgg tgatgtaacc ctctggatca atagagatca gatcgccgga acagtaaaaa
    24841 ccgttggcat caaaggcgct ggcattgtgc tgtggacttt tgtaatagcc gcggaaggtg
    24901 tacggcccgc gcgtcatcag gcgtccgact tccccttgcg gcagtggatt tccttcggca
    24961 tcggcaaccc atacttcgtc atccggacac attgggtaac cctgggtatg gataattttc
    25021 tccgcgctat catcaagtcg ggtgtagttc accagccctt ccgccatgcc aaacacctgc
    25081 tgcaactgac agccaatctc agcgggaata cgcgccgcaa gggtggcaga aagacgtgcg
    25141 ccgccgacct gtaacagttt cagcgaggca agctgcgccc ggctttcgcc ttcgatcagc
    25201 gcctgcaacc acaggctgac tgcgggtggc accagcgcgg taacgttaac ctgatgtttt
    25261 tcaatcaatg ggaaacagag cgtggcgctg ggatcggccg ccagaacaac cgttcctccg
    25321 gcaagaaaga cgcccagcga tcctggcgaa ctcatggcgt agttatgagc cgccgggatc
    25381 gcgcacaggt agcgtgtctg ttgtgtgaac tgacaaatct cgacgctacg acgcacgctg
    25441 tagtagtagt cgttatgagt gcgcgggatc agtttcggtg tgccggtggt gccaccggaa
    25501 agctggaaat aggccacttc atcagcaggt gatggcgtgg cagtaaaatc ctcagccgga
    25561 tggttaatcg catcctgcaa gttatgctca ccgctgtcgt tgagcagttg caccacgcga
    25621 atggaggaat gttctgtgac gaaagtattg aggaaatcat ccccgctaaa cagcgcatgt
    25681 tggcgatcgg caatcagcaa tgcgggttca atctggctgg cataggcgtt cagttcacta
    25741 cgctgatggc tgaacaacgc cagcaccggc gcaacgccca gtttcagcag cgcgaaaaag
    25801 gtaatataca attcagcgac gttacccagt tgtaccagcg cggtttcacc aggtttaatg
    25861 ccctgacggc gtaaactaca cgcgaggtta tccgccgcct gattcagctc ccgataactc
    25921 aactgtcgct cgccgtcgat aaccgcgatg ctgtcactcg cagcatgtcg cgtcagaatg
    25981 tcggtcagcg gcaaatcctg ccagtagcct ttttcccgat agcgacgggc aaactcttcc
    26041 ggccagcggg tgaatggaat gctcatcctc gctccttaat gcaatccaaa aacgttcaac
    26101 atggtagaaa gtttgacgcc tgtttcgcgc cactcaccca acggtgacga cgcaggcaca
    26161 atccccgctc cggcaaacag acgcacctga ttttcccgca gcttcgcgca gcggatggtc
    26221 accacccatt cgccgttacc ttcgctgtca caccaaccca caatgccgcc aaacagttcg
    26281 cggtcgaacg gttccagttc agcaataacc tgggtcgcgg cctgatgcgg gaaaccgctc
    26341 agcgcggggg tcggatgcag cagacaggcc agagtcagtg cgttttcttg cgaattcgct
    26401 ttaccttcaa agggagttgc gagatgccac agcgtcggcg tggtgatcag ctgtggagaa
    26461 gaaggaacgt gtaactcact actgcgttcg cgcagtacct ctttcatcgc ctgagtcacc
    26521 agttcatgtt catggcgatc tttttctgac gccagcagac gattacctgc ttcgcgatcg
    26581 agcacttcat ccggctgacg acgcgcggaa ccggctaacg gaatggagct aaaacgctcg
    26641 ccgtctttac gtagcagcag ttccgggctg gcccccagca ggacgccacc atcagccagc
    26701 ggaacatgga agttgtaact aaccgggttt tgcgcaatca accgttccag caatacgcca
    26761 ctatcaatgg cggcgtcagt ggtgatatca atcaaccgtg acaacaccac tttgtcgacc
    26821 tgcggcgtgg cggtaagtgc ggcggcgcgg gcaaccatct gttcaaacgt ggtttgctcc
    26881 ggaattgcct ggcgttccac cacattcagc gactggctgc gggtgaaacg gcgtgcggaa
    26941 gcttgttttt cctgacggga gaacgactgc caggattcag gaatatacag cgacgaaggc
    27001 tgacgtggat cgaagggaat cgccccgacc atcaccggat ttttgatgcc ctgcgctttg
    27061 gcatcggcaa acagcgcggc gagtttttgc tggaagggac tgtcgggcga atccccgttc
    27121 acagccggtt catcgaagcg ggcgaaacat cctgacgtcg taaaactgcg gtacggcgac
    27181 ataaagaaaa agcgattggg cgcaagtgtt gccatggtct gctgtacttc ctcagccagt
    27241 gacgtatcca tatcatcctc cacaaaatga taaaggcttt aataatgatt atcatttata
    27301 ttttcggtcg ctaacctaaa agcaaacgcg cactatgtca actcttgagg taacgcaatc
    27361 tgcaactcgg ggttgcatct ggttgtggtt acaatgaaaa tgagaagcat tattgatgga
    27421 ttcgcataag cgcaatgtga tgtcctgcgc cgttctgccc cctctccctt ccagggtgag
    27481 ggctggggtg agggttaatg ttcgcaccag tgctggctgt tcccctcacc ctaaccctct
    27541 ccccaaaggg gcgaggggac ggattgtgcg ctttgtcgaa tttgtcatta cgcccttaac
    27601 cttattaata acaggaagct gatttgtgag actcgccccg ctctaccgca acgcccttct
    27661 attaacagga cttttgcttt caggaatagc cgcagttcag gccgctgact ggccgcgtca
    27721 gattactgac agccgtggca cacatacact ggaaagccag ccgcagcgta ttgtttccac
    27781 cagcgtcacc ctgaccggct cactgctggc gattgatgct ccggtgatcg ccagcggcgc
    27841 gaccacgccg aataaccgcg tcgcggatga ccagggcttt ttacgccagt ggagcaaggt
    27901 ggcgaaagaa cgcaaactgc aacggctcta tatcggcgaa ccgagcgccg aagccgttgc
    27961 cgcgcaaatg ccggatctga ttttaattag cgcaaccggc ggggattcgg cgctggcact
    28021 gtatgatcag ctttccacca tcgccccgac attaatcatc aattacgacg acaaaagctg
    28081 gcagtcgctg ttaacgcaac ttggcgaaat taccgggcat gagaaacaag cggcagagcg
    28141 gattgcgcag tttgataagc aactggcggc ggcgaaagag caaatcaaat taccgccgca
    28201 gccggtcact gccattgtct atactgccgc tgcacacagt gccaatctct ggacgccaga
    28261 atcagcacaa gggcagatgc tggaacaact cggctttacg ctggcgaagt tacccgcagg
    28321 gttaaatgcc agccaaagtc agggtaaacg ccatgacatc attcagcttg gtggggaaaa
    28381 tctggctgca gggttaaatg gcgagtcact attcctgttc gccggtgatc agaaagatgc
    28441 cgatgctatt tatgctaatc cgctgctcgc gcacctgcct gcagtacaaa acaagcaggt
    28501 ttatgcgctg ggaaccgaga cgttccgtct ggattactac agcgccatgc aagtgctgga
    28561 taggcttaag gcgctgtttt aagcattaac tgtcggacgc tgtcacctgc ggcggcgtct
    28621 ggcgaaaatg tcgcaactcc accagcacca gcaataacaa cacgccgata atcaacaaac
    28681 caaaaccgct cgcgcttgcg gaagcaaccg gtgtcatcat cgcgcccaaa ccacccagca
    28741 gcgccgcgcc tatggcatcg cccgtcacgt tctgcgccgt ccacaaaccg ttaatccgcc
    28801 ctaacatcgc ttccggggtt tgcgtttgca gcattgtgta ttgcagcaac gagctgaccg
    28861 cactcaacca gccgaacagc gccagacaaa ccacgcctaa aatccacatc ggcatcaggc
    28921 caaacagacc aatggcgagg aacgatccca gcgtggagag cagcatcaat aaccctggtc
    28981 gcgcactatg tgccagcttc ccgctggtta acgcaccaat agccgcgccg agcgggatcg
    29041 ccgcgtagag aaaaccaatc tgtgccgctg acatctgcca gttgtcagcc agcgccggat
    29101 acagtacccg caccgcgctc gccatcgtca ataaaccacc cagcagcgca atcccgccca
    29161 ccagcgggct ggcaagcaga aaacgaaatc ctgccagtaa tgatttcaac ggatgctcac
    29221 gcggctgcgg tggcggtggc aacgccggaa ggcttaacaa cggtagcaag gtaataaacg
    29281 tgcccgccgc cgccagcccg tagttccagg ctacgccacc ggtcgccagc aataaaccgc
    29341 caatcatggg cgaaatcacc gaccccagac gcacggtcaa catggtgatc gccccggcct
    29401 gcattaagtt ttcacgccct accagtgctg gtgtcgccgc caatagcgcc gtaacgccaa
    29461 gcgatgcgaa aaaaccatcc cataaaccaa gtaaatagat tgccagcaat gacggctccg
    29521 gcagcagtgc attaaggcac agtccaatga agccaatgcc acaggtgccg cgcgccagca
    29581 aaatcacttt tttgcgctca tagcgatccg ccagcacacc gccgaccatc aggccaacaa
    29641 acatcgcgcc gccggtcagc gtcaccgaaa gccccacctg ccaggtggaa tgtgtcatca
    29701 tctggatctg caccggcacc gcgacgccga gcaaacccag agacacaatt gagatgaaac
    29761 gagcgaggaa tactgcgcga aacgccgggt gcgttttcaa caggctgagg ttaagcagcc
    29821 aggattgttt attcattaca atgccttgcc atcaaatatt ttaaatacct attcttaggc
    29881 tgcacatgtt aacatatcca aataagatcg ataacgataa ttaatttcat tatcatggaa
    29941 gttcgtatgt ctggttctgt tgccgtgaca cgcgccattg ccgtgcccgg attgctgtta
    30001 ttactgatta tcgcgacggc attaagcctg ctcattgggg caaaatcact ccccgcttcc
    30061 gtagtgctgg aggccttctc cggcacctgc cagagcgccg actgcaccat cgtgctcgac
    30121 gcgcggctgc cgcgtaccct tgccggttta ctggcaggcg gcgcgcttgg ccttgccggg
    30181 gcgttaatgc aaaccctcac ccgaaaccca cttgccgacc ccggcttgct tggcgtgaac
    30241 gccggagcca gctttgccat tgtgctgggt gcggcgctgt ttggttactc ttccgcgcag
    30301 gaacaactgg cgatggcctt cgccggggcg ctggtggcct cattgattgt tgcctttacc
    30361 ggcagtcagg gcggcgggca gttaagtccg gtgcgtttaa ccctggcggg cgtggcgctg
    30421 gcggcggtgc tggaaggact gaccagcggc atcgccctgc ttaatcctga cgtctacgat
    30481 cagttgcgtt tctggcaagc cggttcgctg gatattcgca atctacatac cttaaaagtg
    30541 gtgctgatcc cggtgctgat cgccggagca actgcgctat tactgagtcg cgcgctgaac
    30601 agtttgagcc tcggcagcga caccgcgacg gcgctgggca gtcgcgtggc gcgcacacag
    30661 ttgattggtc tgctggcgat taccgtgctt tgtggtagtg cgacggcaat agttggcccg
    30721 attgccttta ttggcctgat gatgccgcat atggcgcgtt ggctggtggg tgccgatcat
    30781 cgctggtcgc tgcccgtcac gctacttgct acccctgccc tgctgctgtt tgccgatatc
    30841 atcgggcggg tgattgtgcc cggcgaactg cgcgtttctg tggtcagtgc gtttattggt
    30901 gcaccggtgc tgatcttcct cgtgcgacgt aaaacgcgag gtggtgcatg atttacgtct
    30961 ctcgccgatt actcatcacc tgtttgctgc tggtttccgc ctgtgtggtt gcaggtatct
    31021 ggggattacg cagcggtgcc gtcacgctgg aaacctcgca ggtattcgcc gcgctgatgg
    31081 gcgatgcgcc gcgcagtatg acgatggtgg tcaccgaatg gcgtttacca cgcgtgctga
    31141 tggcgctgtt gattggcgca gcactgggcg tcagtggcgc gatttttcag tcgctgatgc
    31201 gtaacccgct cggcagccct gacgtaatgg gctttaacac cggggcgtgg agcggcgtgc
    31261 tggtggcgat ggtgctgttt ggtcaggacc tgacggctat cgcgctgtca gcaatggtgg
    31321 gcggcattgt cacttcgctg ctggtctggc tgctcgcctg gcgcaacggc atcgacacct
    31381 ttcggttgat tattatcggt atcggccttc gcgccatgct ggtggccttt aatacctggc
    31441 tgttgctgaa agcgtcttta gaaacggcgc taacagcagg tttgtggaat gccggatcgc
    31501 tcaacggcct gacgtgggca aaaacctcgc cttccgcacc catcattata ttgatgctca
    31561 ttgccgccgc cttactggta cgccggatgc gcttgctgga aatgggcgat gataccgcgt
    31621 gtgcgctggg cgtcagcgtc gaacgttcgc gtctgttaat gatgctggtt gcagtggtgc
    31681 ttaccgctgc ggcaacagcg cttgccgggc cgatttcctt tattgcttta gtcgcaccgc
    31741 acattgcccg acgcattagc ggcaccgctc gctgggggct aacccaggcg gcgctatgcg
    31801 gggcgctgtt actgctggcg gccgatctct gcgcccaaca actgtttatg ccgtatcaac
    31861 ttccggttgg cgtcgttacc gtcagcctcg gcggtattta ccttatcgtc ttgttaattc
    31921 aggagtctcg caaaaaatga ccgaatcagt agcccgtttg cgcggcgaac agttaaccct
    31981 gggatatggc aaatataccg ttgcggaaaa tctgactgta gaaatacctg atggtcactt
    32041 cacggcaatt atcgggccaa atggctgcgg taaatccacg ttactgcgta ccttaagccg
    32101 cctgatgacg cctgctcatg ggcatgtctg gctggatggc gagcacattc aacattacgc
    32161 cagtaaagag gttgcacgcc ggattggtct gttggcgcaa aatgctacca cgccgggcga
    32221 tatcaccgtg caggagctgg tggcgcgtgg acgttatccg catcaaccgc tgtttacccg
    32281 ctggcgcaaa gaggatgaag aagcggtaac gaaagcaatg caggccacgg gaataactca
    32341 tctggcagat caaagcgtgg ataccctttc tggcggacaa cgccagcgag cgtggatcgc
    32401 gatggtgctg gcccaggaaa cggcaattat gctgctcgac gaacccacga cctggctgga
    32461 tatcagtcat cagattgatt tgctggagtt gttaagcgaa ctgaaccgcg aaaaaggcta
    32521 taccctggcg gcggtgctgc acgatcttaa tcaggcctgt cgttacgcca gccatttgat
    32581 tgcattgcgg gaagggaaaa ttgttgctca gggagcgccg aaggagattg tcactgctga
    32641 actgattgag cgcatttatg gtctgcgctg catgatcatt gacgatccag ttgccggaac
    32701 gccgcttgtg gtgccgctcg gacgaacggc accttcaacc gcaaatagtt aaactaagtg
    32761 gtctgccatc atggcatcct gttttctgga tgccatcgca tagcgcaaca gcacgccacc
    32821 acaagccacc atcccgccga tcaacgcgga aaggatcaca ataatcgcct tacccggacc
    32881 gtcttttttc actggcaatg acgggcttaa ctgatattta aacggcgtaa aattcacatc
    32941 gttgacatgt gcttttgtta attgctcgac aagatactgc cgattacgta attcaccgtt
    33001 cagttccgca acgtcagtga ccgctttttc tatttccagt ttgcgttcaa taccgtctgc
    33061 accgagagaa atagaaaaat cggggtcatc tttaacggcc tgaccattac tgtaaacggg
    33121 ctttttaatt cctgccgcgt tggcaatgtc gagtgaataa ttgaggcgct gaatgtttgc
    33181 atcaagttga tttttcgttt taatgcgatc ctgagccagt ttttcttttt caaactgggt
    33241 tttgatctcc agtttattac ggacgttttc tagcgactct ttcaccacca acgtagagat
    33301 ataatcgata tacccgctca aaacggtctg cgcctcttca ctggttggcg cggtaaaact
    33361 tagcgtccag gaggtataca gtgacggttc atcttttttc ttactggcat tgtcatcaac
    33421 cgctttcatt ttttcgctca atgcgacaat tgcgcgatgc aaatccagtt cgtcgatttt
    33481 cgcctctttt aattggtcca tcacataagg tgatgaacgc aggtactctt ccagcaagct
    33541 aaccgactga aacttcttga taaacaggtt aaatgcttct gtacgatcaa ttttgatatc
    33601 cagatccagc acacgaagct tagtgaatga tttctccaac tcttgccact gaacaggttc
    33661 tggaggcgtg acaaccgccg cgctggtcca tttttgcggc aggatgaaag agatcagcaa
    33721 gcctgcgcag gcaaacgcaa aaacgaccgc catgaccgtt tttttggccc gccataaaac
    33781 tgagattaga ttaagtaaat caatttcatt attactggac gacgccagag gataatcggg
    33841 aaaatgagcg tcacttccct gtttaatatt cagtgatgac atggggtata acctgaaaat
    33901 gagtccaata gggggaaatc tccacggcgc tcactttacc agttggtgat aattatccga
    33961 agctgaagtt tgtaaattcc ttccactgaa tgcaacattc actctattta agagaaatat
    34021 tcatcaaacc tataaatcaa acaaataaaa aacccataat tattttctgt aattatgggt
    34081 ttataaataa tattaattta cctgtttagc gttgcgcgaa taatcggccc aattttttca
    34141 aacgtccctg gagagataat atccacatgc gcacaatcct gacgatagat atccagctcc
    34201 gctatccacg gcgaccaggc gcgttcggga ctcatacctt cctgaagtgt gcgttcagca
    34261 acaaacagcg tcgctttacc gtcaaacggt acgctatgag cagtcgtcag caggcgcaca
    34321 gcatcagcgt agttgccttc aatggtggta aacaactccg ttgaagtact tccctgctgt
    34381 gctgccagga aggcctcgcg ttcgcggtta atctccgcca gcacttccgg gtccagacca
    34441 ttagcttctt tttcctgcca gttttgcgtt tctggcggcc aggtatccag caagccaaga
    34501 aatgccacct gttcgccacg ggcacgcagt cgcgccgcaa taccctgcgc cagcgtaccg
    34561 ccaagggaat accccagcag gtaataaggg ccatgcggtt gttgttcaag taacgttgcc
    34621 agatgcgctt cgcagacttc atccaggttt gccgccgtct gcatggggcc attggggcgc
    34681 ggtgactgaa tgccgataat cgaccattgt ggatcgagat aacgcgagag cacgctgaac
    34741 tgccaggcaa aaccggacgc aggatggaaa caaaacagcg tcgggccatt accttcacgc
    34801 aacggcagaa tggtttcgaa tcccatacgc cgggtgctgt cttcttcagc atcaataatc
    34861 gttgccagtt tggcgacagt tgacgcgacc atcacttgcc ccggcgtcac ctggcgggca
    34921 acctgccgac ttaactgcgc tgccagtttc attgccagta gcgaatgacc gccaagcgcg
    34981 aagaaatcag catcggcatc ctgcacgtca caccccagca acgacgagaa tgccgcggcg
    35041 ataatcgttt cactgcccgc tttcggcgca cgccctggcg cttgtgcctt cagttcaggc
    35101 aacggtaagg ctttgcgatc cagcttgccg ttggcgctaa gtggtaactg tggaagttgc
    35161 agcagaacca ccggtaccat atgtggtggc aatgtttcac gaagctgcgc ctgcaatgcg
    35221 ctggtatcca acggcaggcc cgattgcgac accagatagc ccaccaattg acgcgcatca
    35281 ccaccggtgg cagccgcctg gttaatcaca caggcgtggg taacggcttg ttcgacatcc
    35341 ggcagcgcct gcatcacgcg atcgatttcg cccagttcga tacgctgccc gcgaattttt
    35401 agctgatcat cactgcgccc gaggtactcc accgcgccgt tatccagcca gcgggcaacg
    35461 tctccggtac ggtacatccg ttcacctggg gcaaaaggat cggcaataaa gcggctggcg
    35521 gtcagatcgg ggcgtccgag atagccctgc gccagttgaa tgccagtgag atagagatca
    35581 cccgccacac ccggcggcac cggatgcatc atcgcatcaa gaatacgcag acccgtattc
    35641 cataccggat aaccaatcgg cacactgctg ccgcgcacct gtgccagttc ctcgccaaaa
    35701 gccggatacc agctgacatc taccgccgct tccgtcgggc catatagatt atgcaacggc
    35761 gcgccagtta actgttgcca ttcgcggcat aaatcagccg gtaaggcctc accactacag
    35821 aaaacctgtt tcaacgtcgc gcaactctgg cgagcggttt gcggcgtcag cgaggcaaca
    35881 aatgccgcca gcatcgacgg cacaaagtgc gtggtcgtta cgccatattc ggcaaagaat
    35941 tgctgcatag cgagcgggtc gcggtgcgct tccggttcag ccatcaccag ttttgcccct
    36001 gcgataaacg gccagaaaaa ctcccacacc gagacatcaa aactgcacgg cgttttttgg
    36061 gcaacgacat cttcgcctgt aagcggataa tgattttgca tccaaagcag gcggttgacg
    36121 atagccgtct gcccgaccat tacccctttc ggcctgccgg tggagccaga ggtaaagatg
    36181 atataagccg tgtgatgcgg ttgtgaaagt tgcagcggcg cactgccctg cggtgtaagc
    36241 ggggcgttat agcaaaggct tgttaaattg ggaacatcgc taaagcgcgg cagttgatcg
    36301 tcggtggtaa ttaacagcga cggacgcgca tcttccagca tcattttcag gcgatcgtcc
    36361 ggatagccgg tatccagcgg tagccaggcc gctccagctt caactatcgc atggagtgcc
    36421 agggtcaaaa agaccgagcg cggtagtgcc accgccacgc tgtcccctgg tttaacgccg
    36481 cgctcacgca gcagattcgc cagcgccacc acctgctcgc gcatttcccg atagctgaac
    36541 aggtaacgcg catctgccag cgccggagca tccggtgttt ttgccgcttg ttctgccacc
    36601 agcgcgctaa gcgtggtttc tggaatctca acctgagtgg cgttgagctg cgccagctgc
    36661 gcatactcac ctggcagcat aatatcgaca tcgccgcaca acagcgccgg atccgcggcg
    36721 aactgggcaa tcagcatttt caggcgttca gcatgctgga ttaacgttgg ctcatcgtaa
    36781 cgctgtttat tggcgaggat ctcaatactc aaatcaccgt gtacatccgg gaacagggcc
    36841 agttcaaggt cattaaccgg accggttgcc agggtatggg tttgcgcctg aacatcagga
    36901 atatccagtt ggtaatcaaa taccttgata ttgagtaccg gaccaaacag cggttcatca
    36961 cctgccgctc gccc
//
LOCUS       DACAOP010000040        36654 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.040, whole genome shotgun sequence.
ACCESSION   DACAOP010000040 DACAOP010000000
VERSION     DACAOP010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36654
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.040"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            47..121
                     /locus_tag="IT892_002238"
     tRNA            47..121
                     /locus_tag="IT892_002238"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:79..81,aa:Gln,seq:ctg)
     gene            complement(275..1450)
                     /gene="ubiF"
                     /locus_tag="IT892_002239"
     CDS             complement(275..1450)
                     /gene="ubiF"
                     /locus_tag="IT892_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol
                     hydroxylase"
                     /protein_id="HAP3135452.1"
                     /translation="MTNQPTEIAIVGGGMVGGALALGLAQHGFAVTVIEHAEPAPFVA
                     DSQPDVRISAISAASVSLLKGLGVWDAVQAMRCHPYRRLETWEWETAHVVFDAAELKL
                     PLLGYMVENTVLQQALWQALEAHPKVTLRVPGSLIALHRHDDLQELELKGGEVIRAKL
                     VIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPGDSTWQQFTPDGPRAFLPL
                     FDNWASLVWYDSPARIRQLQNMNMAQLQAEIAKHFPSRLGYVTPLAAGAFPLTRRHAL
                     QYVQPGLALVGDAAHTIHPLAGQGVNLGYRDVDALIDVLVNARSYGEAWASYPVLKRY
                     QMRRMADNFIMQSGMDLFYAGFSNNLPPLRFMRNLGLMAAERAGVLKRQALKYALGL"
     gene            1596..3020
                     /gene="miaB"
                     /locus_tag="IT892_002240"
     CDS             1596..3020
                     /gene="miaB"
                     /locus_tag="IT892_002240"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HAP3135453.1"
                     /translation="MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVL
                     LLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDII
                     FGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
                     CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSF
                     ADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNL
                     MGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSY
                     SFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGT
                     SRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRV
                     AETPESVIARTRKENDLGVGYYQP"
     gene            3134..4213
                     /locus_tag="IT892_002241"
     CDS             3134..4213
                     /locus_tag="IT892_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAP3135454.1"
                     /translation="MFSFRRHTDKRNGLNIDTREITLEPADNARLLSLCGPFDDNIKQ
                     LERRLGIEINRRDNHFKLTGRPICVTAAADILRSLYVDTAPMRGQIQDIEPEQIHLAI
                     KEARVLEQSAESVPEYGKAVNIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTG
                     KTYLAVAAAVDALERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFE
                     MLGFEKVEKLIERNVIEVAPLAYMRGRTLNDAFIILDESQNTTIEQMKMFLTRIGFNS
                     KAVITGDVTQIDLPRNTKSGLRHAIEVLADVEEISFNFFHSEDVVRHPVVARIVNAYE
                     AWEEAEQKRKAALAAERKREEQEQK"
     gene            4210..4677
                     /gene="ybeY"
                     /locus_tag="IT892_002242"
     CDS             4210..4677
                     /gene="ybeY"
                     /locus_tag="IT892_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014169133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAP3135455.1"
                     /translation="MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIR
                     VVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGK
                     PLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE"
     gene            4767..5645
                     /gene="corC"
                     /locus_tag="IT892_002243"
     CDS             4767..5645
                     /gene="corC"
                     /locus_tag="IT892_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308723.1"
                     /note="CorC(YbeX) belongs to the Cyclin M Mg2+ Exporter
                     (CNNM) family, and was characterized as belonging to a set
                     of three proteins, at least one of which must be present
                     for CorA to function; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family magnesium/cobalt transport protein
                     CorC"
                     /protein_id="HAP3135456.1"
                     /translation="MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDS
                     GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR
                     FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
                     QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA
                     SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ
                     VHVKIPDDSPQPKLDE"
     gene            5670..7208
                     /gene="lnt"
                     /locus_tag="IT892_002244"
     CDS             5670..7208
                     /gene="lnt"
                     /locus_tag="IT892_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HAP3135457.1"
                     /translation="MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGL
                     QALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLS
                     LYTGLFAGVLSRLWPKTTWLRVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPL
                     KGLAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYIQWFTPQP
                     EKTIQVSMVQGDIPQSLKWDEGQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEIN
                     QQPFLKALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLGKGAPYSYESADRYN
                     KNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSANGIELTAAICYEIIL
                     GEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITA
                     VIGPQGEIQAMIPQFTREVLTTNVTPTTGLTPYARTGNWPLWVLTALFGFAAVLMSLR
                     QRRK"
     gene            7605..8513
                     /gene="gltI"
                     /locus_tag="IT892_002245"
     CDS             7605..8513
                     /gene="gltI"
                     /locus_tag="IT892_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter
                     substrate-binding protein GltI"
                     /protein_id="HAP3135458.1"
                     /translation="MQLRKPATAILALALSAGLAQADDAAPAAGSTLDKIAKNGVIVV
                     GHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLL
                     QNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFANLKDKAVVVTS
                     GTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKK
                     PDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPP
                     KNLNMNFELSDEMKALFKEPNDKALN"
     gene            8683..9423
                     /gene="gltJ"
                     /locus_tag="IT892_002246"
     CDS             8683..9423
                     /gene="gltJ"
                     /locus_tag="IT892_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltJ"
                     /protein_id="HAP3135459.1"
                     /translation="MSIDWNWGIFLQQAPFGNTTYLGWIWSGFQVTIALSICAWIIAF
                     LVGSFFGILRTVPNRFLSGLGTLYVELFRNVPLIVQFFTWYLVIPELLPEKIGMWFKA
                     ELDPNIQFFLSSMLCLGLFTAARVCEQVRAAIQSLPRGQKNAALAMGLTLPQAYRYVL
                     LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQAGKLLDYSAHAWESFTAITLA
                     YVLINAFIMLVMTLVERKVRLPGNMGGK"
     gene            9423..10097
                     /gene="gltK"
                     /locus_tag="IT892_002247"
     CDS             9423..10097
                     /gene="gltK"
                     /locus_tag="IT892_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltK"
                     /protein_id="HAP3135460.1"
                     /translation="MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVM
                     RLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMV
                     AFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
                     QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSY
                     LKRRTA"
     gene            10097..10822
                     /gene="gltL"
                     /locus_tag="IT892_002248"
     CDS             10097..10822
                     /gene="gltL"
                     /locus_tag="IT892_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter ATP binding
                     protein GltL"
                     /protein_id="HAP3135461.1"
                     /translation="MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLI
                     KTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQ
                     VKVLKRDKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
                     DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIVEDS
                     PKDAFFDDPKSDRAKDFLAKILH"
     gene            10940..11875
                     /gene="rihA"
                     /locus_tag="IT892_002249"
     CDS             10940..11875
                     /gene="rihA"
                     /locus_tag="IT892_002249"
                     /EC_number="3.2.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-specific ribonucleoside hydrolase
                     RihA"
                     /protein_id="HAP3135462.1"
                     /translation="MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEK
                     TLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPTFAPQNC
                     TAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWT
                     PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAE
                     LLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTSVERWVGVETQGKYTQGMTVV
                     DYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA"
     gene            11959..13629
                     /locus_tag="IT892_002250"
     CDS             11959..13629
                     /locus_tag="IT892_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HscC"
                     /protein_id="HAP3135463.1"
                     /translation="MDNAELAIGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIIS
                     MDENNHILVGKPAVSRRTSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSL
                     KEDAEEFLQRPIKDVVISVPAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGL
                     HTQQNTRSLVFDLGGGTFDVTVLEYATPVIEVHASAGDNFLGGEDFTHMLVDEVLKRA
                     DVARTTLNESELAALYACVEAAKCSNQSPLHIRWQYQEETRECEFYENELEDLWLPLL
                     NRLRVPIEQALRDARLKPSQIDSLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIV
                     ALGAAIQAACRLRSEDIEEVILTDICPYSLGVEVNRQGVSGIFSPIIERNTTVPVSRV
                     ETYSTMHPEQDSITVNVYQGENHKVKNNILVESFDVPLKKTGAYQSIDIRFSYDINGL
                     LEVDVLLEDGSVKSRVINHSPVTLSAQQIEESRTRLSALKIYPRDMLINRTFKAKLEE
                     LWARALGDEREEIGRVITDFDAALQSNDMARVDEVRRRASDYLAIEIP"
     gene            complement(13689..15140)
                     /gene="djlC"
                     /locus_tag="IT892_002251"
     CDS             complement(13689..15140)
                     /gene="djlC"
                     /locus_tag="IT892_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlC"
                     /protein_id="HAP3135464.1"
                     /translation="MKTCWQILEIESTTQIDIIRQAYLARLPLCHPETDPQGFKALRQ
                     AYEEALRLAVNPVEEADDEEKDAAAEHEILRAFRTLLDSESDRFQPSAWQKFIQQLNT
                     WNMEDVDQLRWPLCAIAIEARYLSLNCASLLAERLNWHSFNDSEGMDEEEREAFLEAI
                     QAGDCFDFLSLLEYPIALQNQTVEYYFALERCCRYHPDYVTAFLAMEGPWLIPDDAKL
                     HRKLLRWYSSVQTGMAELIPVAQQWQTEEPESEDARYYLCAQRLYCGEGESLLADLCA
                     YWESYPSTQADNLLLQWSKRHCPDYFALLVMVIEARSMVDAQGQPLKYVPGESARTRL
                     LWAEILHSGKLSPLGQSFIESLFFKRKAWAWWKSRVGSETEQDSPFLDLYRVAEQVVL
                     EAFPKQEMLARLNTRLEGGDAHPLEAIVTRMLLTKVKLEPEDEDVDEPTPENHEEKND
                     EGEKPQSITSIIKISLTVLVIGYALGKIAMLFS"
     gene            complement(15137..15844)
                     /locus_tag="IT892_002252"
     CDS             complement(15137..15844)
                     /locus_tag="IT892_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HAP3135465.1"
                     /translation="MNKEEQYLLFALSAPMEILNQGCKPAHDSPKMYTGIKEFELSSS
                     WGINNRDDLIQTIYQMTDDGHANDLAGLYLTWHRSSPEEWKALIAGGSERGLIYTQFV
                     AQTAMCCGEGGIKAWDYVRMGFLSRVGVLNKWLTEEESLWLQSRVYVRAHHYYHSWMH
                     YFSAYSLGRLYWQSSQCEDNTSLREALTLYKYDSAGSRMFEELAAGSDRFYATLPWQP
                     LTVQSECPVTLKDVSDL"
     gene            15946..16500
                     /locus_tag="IT892_002253"
     CDS             15946..16500
                     /locus_tag="IT892_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HAP3135466.1"
                     /translation="MNKKLMYIFAIFIVAAITCISQPKKTTLRDKAMVNYAFDYLSSP
                     GSLPFTTAATELSAIHGHSTSQYRLGEFYLHGSDGKPLDYTQARYWYEQSAEQENPRA
                     QSKLGWIYLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQ
                     KWLKLAAKQHYKNAERLLAGLPAH"
     gene            complement(16510..17937)
                     /locus_tag="IT892_002254"
     CDS             complement(16510..17937)
                     /locus_tag="IT892_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="HAP3135467.1"
                     /translation="MKNCWKILDIEETTDVDIIRRAYLALLPSFHPETDPQGFKQLRQ
                     AYEEALRIAQSPAKSVWQPEEYEVAEHEILLAFRALLASDSERFLPSAWQRFIQQLNY
                     CSMEEIDELRWSLCTIAMNTAHLSFECVVLLAERLRWLQEENTGEIDEEELESFLYAI
                     AKGNVFNFQTILHLPVAVQNDTIDFYQMFARIWSSHPQWLTLYLAQHRAVIIPDDAKL
                     HRNLLRWYSAGRLDIPELLDYAQSWRETEPDNEDAPYYEYAQRVYCGEGESLLAELCD
                     YWREYPSTQADALMLQWCRQHRVDYYPLLVMMIEARDLVNDQGKPLLYVPGDSARTRF
                     HLYEILSDEKLSALGRSLVEMVLHKGRKPRISLTRDTEHTLWPLYLVAKQLVQACQPT
                     EESLMPIVSRLDAENRCPLEALIIRRLLIQAANFTEKQTVEPEPQPQPMPVDDGGPGC
                     LGIIKIIFYIFIFAGLIGKILHLFG"
     gene            complement(17934..18641)
                     /locus_tag="IT892_002255"
     CDS             complement(17934..18641)
                     /locus_tag="IT892_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HAP3135468.1"
                     /translation="MDMESQKILFALSTPMEIRNECCLPSHSSPKMYLGTCFFDLSSS
                     WGIDDRDDLLRTIHRMIDNGHAARLAGFYHRWFRYSPCEWRDYLAELNEQGQAYAQFV
                     ASTAECCGEGGIKAWDYVRMGFLSRMGVLNNWLSEEESLWIQSRIHLRALRYYSNWRQ
                     YFAGYTFGRQYWQSPEDDHLPLLREFLARKEYDDSGNDMFYQLFASDDAYYPTLSWQP
                     LAYYSACPETLKDMSDL"
     gene            18805..19782
                     /locus_tag="IT892_002256"
     CDS             18805..19782
                     /locus_tag="IT892_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415177.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEL1-like repeat protein"
                     /protein_id="HAP3135469.1"
                     /translation="MIFTSSCCDNLSIDEIIERAEKGDCEAQYIVGFYYNRDSAIDSP
                     DDEKAFYWLKLAAEQGHCEAQYSLGQKYTEDKSRHKDNEQAIFWLKKAALQGHTFASN
                     ALGWTLDRGEAPNYKEAVVWYQIAAESGMSYAQNNLGWMYRNGNGVAKDYALAFFWYK
                     QAALQGHSDAQNNLADLYEDGKGVAQNKTLAAFWYLKSAQQGNRHAQFQIAWDYNAGE
                     GVDQDYKQAMYWYLKAAAQGSVGAYVNIGYMYKHGQGVEKDYQAAFEWFTKAAECNDA
                     TAWYNLAIMYHYGEGRPVDLRQALDLYRKVQSSGTRDVSQEIRETEDLL"
     gene            complement(19852..20334)
                     /locus_tag="IT892_002257"
     CDS             complement(19852..20334)
                     /locus_tag="IT892_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon-containing protein"
                     /protein_id="HAP3135470.1"
                     /translation="MNKVAQYYRELVASLSERLRNGERDIDALVEQARERVIKTGELT
                     RTEVDELTRAVRRDLEEFAMSYEESLKEESDSVFMRVIKESLWQELADITDKTQLEWR
                     EVFQDLNHHGVYHSGEVVGLGNLVCEKCHFHLPIYTPEVLTLCPKCGHDQFQRRPFEP
                     "
     gene            20569..23151
                     /gene="leuS"
                     /locus_tag="IT892_002258"
     CDS             20569..23151
                     /gene="leuS"
                     /locus_tag="IT892_002258"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008456064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAP3135471.1"
                     /translation="MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYP
                     SGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTY
                     DNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
                     NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKT
                     MQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNP
                     ELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGA
                     VMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDH
                     EAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQL
                     PVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQY
                     KEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQ
                     GMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSK
                     NNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTA
                     KGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAP
                     TDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVED
                     STLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLN
                     LVVG"
     gene            23166..23747
                     /gene="lptE"
                     /locus_tag="IT892_002259"
     CDS             23166..23747
                     /gene="lptE"
                     /locus_tag="IT892_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HAP3135472.1"
                     /translation="MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPN
                     GPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIM
                     TVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLP
                     SIRAADIRSDEEQTSTTTDTPATPARVSTTLGN"
     gene            23747..24778
                     /gene="holA"
                     /locus_tag="IT892_002260"
     CDS             23747..24778
                     /gene="holA"
                     /locus_tag="IT892_002260"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAP3135473.1"
                     /translation="MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAA
                     QGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTLTG
                     LLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRWVAARAKQLNL
                     ELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWV
                     DALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKH
                     RVWQNRRGMMGEALNRLSQTQLRQAVQLLTRTELTLKQDYGQSVWAELEGLSLLLCHK
                     PLADVFIDG"
     gene            24780..25421
                     /gene="nadD"
                     /locus_tag="IT892_002261"
     CDS             24780..25421
                     /gene="nadD"
                     /locus_tag="IT892_002261"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAP3135474.1"
                     /translation="MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPP
                     HRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPL
                     AFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPED
                     LHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR"
     gene            25445..26056
                     /locus_tag="IT892_002262"
     CDS             25445..26056
                     /locus_tag="IT892_002262"
                     /EC_number="3.1.3.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin/alpha-ribazole phosphatase"
                     /protein_id="HAP3135475.1"
                     /translation="MRLWLIRHGETQANIDGLYSGHAPTPLTARGIEQAQNLHTLLHG
                     VSFDLVLCSELERAQHTARLVLSDRQLPVQIIPELNEMFFGDWEMRHHRDLMQEDAEN
                     YSAWCNDWQHAIPTNGEGFQAFSQRVERFIARLSEFQHYQNILVVSHQGVLSLLIARL
                     IGIPAEAMWHFRVDQGCWSAIDINQKFATLRVLNSRAIGVENA"
     gene            26316..26633
                     /gene="rsfS"
                     /locus_tag="IT892_002263"
                     /gene_synonym="rsfA"
     CDS             26316..26633
                     /gene="rsfS"
                     /locus_tag="IT892_002263"
                     /gene_synonym="rsfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308702.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAP3135476.1"
                     /translation="MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTS
                     SRHVMSIADHVVQESRAAGLLPLGVEGENSADWIVVDLGDVIVHVMQEESRRLYELEK
                     LWS"
     gene            26637..27104
                     /gene="rlmH"
                     /locus_tag="IT892_002264"
     CDS             26637..27104
                     /gene="rlmH"
                     /locus_tag="IT892_002264"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010618862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAP3135477.1"
                     /translation="MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRG
                     KNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLI
                     GGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE"
     gene            27135..29036
                     /gene="mrdA"
                     /locus_tag="IT892_002265"
     CDS             27135..29036
                     /gene="mrdA"
                     /locus_tag="IT892_002265"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-transpeptidase MrdA"
                     /protein_id="HAP3135478.1"
                     /translation="MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQI
                     VRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTL
                     DALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKG
                     YKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVL
                     HGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVT
                     DPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKP
                     YVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFF
                     YQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIP
                     VGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIH
                     SGYWELAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAE
                     RLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAEN
                     PAVAAAEDH"
     gene            29039..30151
                     /gene="mrdB"
                     /locus_tag="IT892_002266"
                     /gene_synonym="rodA"
     CDS             29039..30151
                     /gene="mrdB"
                     /locus_tag="IT892_002266"
                     /gene_synonym="rodA"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885876.1"
                     /note="rod shape-determining protein RodA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase MrdB"
                     /protein_id="HAP3135479.1"
                     /translation="MTDNPNKKTFWDKVHLDPTMLLILLALLVYSALVIWSASGQDIG
                     MMERKIGQIAMGLVIMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRW
                     LDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTGIALVLIFMPTLLVAAQPDL
                     GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPE
                     SDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVG
                     ILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGV
                     PLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV"
     gene            30162..31250
                     /gene="rlpA"
                     /locus_tag="IT892_002267"
     CDS             30162..31250
                     /gene="rlpA"
                     /locus_tag="IT892_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic peptidoglycan transglycosylase RlpA"
                     /protein_id="HAP3135480.1"
                     /translation="MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEIS
                     GADPRFEPLNATANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEAFD
                     PTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSN
                     NTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVSGPQGDILP
                     VSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPA
                     MVTPQAVSQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGP
                     FASKAEASTLQQRLQTEAQLQSFITTAQ"
     gene            31389..32600
                     /gene="dacA"
                     /locus_tag="IT892_002268"
     CDS             31389..32600
                     /gene="dacA"
                     /locus_tag="IT892_002268"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase DacA"
                     /protein_id="HAP3135481.1"
                     /translation="MNTIFSARIMKRLALTTALCTAFISAAHADDLNIKTMIPGVPQI
                     DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGN
                     DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG
                     LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT
                     FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG
                     REAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRM
                     KDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID
                     YIKLMFHHWFG"
     gene            32710..32973
                     /locus_tag="IT892_002269"
     CDS             32710..32973
                     /locus_tag="IT892_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HAP3135482.1"
                     /translation="MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYT
                     PTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL"
     gene            33074..33715
                     /gene="lipB"
                     /locus_tag="IT892_002270"
     CDS             33074..33715
                     /gene="lipB"
                     /locus_tag="IT892_002270"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415163.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HAP3135483.1"
                     /translation="MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHY
                     PVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELV
                     TLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
                     SPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA"
     gene            33974..34927
                     /locus_tag="IT892_002271"
     CDS             33974..34927
                     /locus_tag="IT892_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415162.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HAP3135484.1"
                     /translation="MDSNNQIEPCLSRKSSEGKPQIFTTLRNIDLNLLTIFEAVYVHK
                     GIVNAAKVLNLTPSAISQSIQKLRVIFPDPLFIRKGQGVTPTAFAMHLHEYISQGLES
                     ILGALDIEGSYDKQRTITIATTPSVGALVLPVIYRAIKTHYPQLLLRNPPISDAENQL
                     SQFQTDLIIDNMFCTNRTVQHHVLFTDNMVLICREGNPLLSLEDDRETIDNAAHVLLL
                     PEEQNFSGLRQRVQEMFPDRQINFTSYNILTIAALVANSDMLAIIPSRFYNLFSRCWP
                     LEKLPFPSLNEEQIDFSIHYNKFSLRDPILHGVIDVIRNAF"
     gene            35136..36101
                     /gene="lipA"
                     /locus_tag="IT892_002272"
     CDS             35136..36101
                     /gene="lipA"
                     /locus_tag="IT892_002272"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HAP3135485.1"
                     /translation="MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIK
                     LPADSTRIQGIKAAMRKNDLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCD
                     VAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKS
                     PQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLL
                     ERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQ
                     RYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK"
     gene            complement(36202..36405)
                     /gene="tatE"
                     /locus_tag="IT892_002273"
     CDS             complement(36202..36405)
                     /gene="tatE"
                     /locus_tag="IT892_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatE"
                     /protein_id="HAP3135486.1"
                     /translation="MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMN
                     DDDAAAKKGADVDLQAEKLSHKE"
     gene            complement(36534..>36654)
                     /locus_tag="IT892_002274"
     CDS             complement(36534..>36654)
                     /locus_tag="IT892_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP3135487.1"
                     /translation="AASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL"
BASE COUNT         9188 a         9310 c         9263 g         8893 t
ORIGIN      
        1 attctgaatg tgtcgaatat gttcggcaaa ttcaaaacca atttgttggg gtatcgccaa
       61 gcggtaaggc accggattct gattccggca ttccgaggtt cgaatcctcg taccccagcc
      121 acattaaaaa agctcgcttc ggcgagcttt ttgcttttct gcgttcattc aatgtcgaat
      181 gcgatgttga cacgtcttat ccttcaatgt cggatgcgac gctgccgcgt cttatccgac
      241 ctacggttgg cacgcatccg gcaatgttgt aaggctacaa ccctaacgca tatttcagcg
      301 cctgacgttt caacacgcca gcacgctccg ccgccattaa cccgagatta cgcataaaac
      361 gcagtggtgg cagattattg ctgaatccgg cataaaacag atccataccg ctttgcataa
      421 tgaagttatc cgccatgcgc cgcatctggt aacgcttgag gacaggataa ctggcccacg
      481 cttcgccgta gctgcgggcg ttgaccagaa catcaatcag ggcatcgaca tcacgataac
      541 caagattcac tccctgcccc gccagcggat ggatggtatg cgcggcatcg cccaccagcg
      601 caagccctgg ctgcacgtac tgcaacgcat ggcgacgcgt cagcggaaac gcaccagcgg
      661 caagcggtgt aacgtaaccc agacgcgacg ggaaatgctt cgcgatttcc gcctggagct
      721 gtgccatatt catattctgc aactggcgaa tacgcgccgg agagtcatac cacaccagcg
      781 atgcccagtt atcaaacaac ggcagaaacg cacgcggtcc gtccggagta aattgctgcc
      841 aggtgctgtc gccgggatcg ttctcgcact ggacgctaat caacatgcac gactgcgcat
      901 actgccatgc atgaacgcca attcccgcca tctgccgcac ctgcgaattt gcgccgtcgg
      961 caccaatcac cagcttcgcg cgaatcactt caccgccttt cagctccagc tcctgaagat
     1021 catcatggcg atgcagcgca atcagcgagc ctggcacacg taacgttact ttcggatgcg
     1081 cttccagcgc ctgccacaac gcctgttgca ggacagtgtt ttccaccata tagccaagca
     1141 gcggtagctt aagttcagcg gcgtcaaaca ccacatgcgc cgtttcccac tcccacgttt
     1201 ccagtctgcg gtaaggatgg caacgcatag cctgtactgc atcccagacc cctaaccctt
     1261 taagcaatga taccgaagcc gcgctgatcg ccgagatccg cacgtccggt tggctatcag
     1321 cgacaaacgg cgctggttct gcgtgctcga tcaccgttac cgcaaatccg tgctgtgcca
     1381 gccccagcgc cagtgcgccg ccgaccattc ctccgccgac aatggcaatt tccgttggtt
     1441 gatttgtcat ggtcaatcat cctgttagca atatgcttta agtttacagg atttttaccc
     1501 ctaagggctg ataacgctca tactggtcac aacggcagca aagcattaca ctatgcgccc
     1561 tgcattcctg gctactattt cgcaagagca agtcgatgac caaaaaactc catattaaaa
     1621 cctggggctg tcagatgaac gagtacgatt catcgaagat ggccgatctg ctggatgcca
     1681 cccacggcta tcaactgacc gacgtggcgg aagaagcgga tgtgctgctg ctgaacacct
     1741 gctcaatccg cgagaaggct caggaaaaag tcttccatca gttgggtcgc tggaaactgt
     1801 taaaagagaa gaatccagac ctgattatcg gcgtcggtgg ctgcgtggca tcgcaagaag
     1861 gcgagcacat tcgccagcgc gcccactatg tcgatattat ttttgggccg caaacgctgc
     1921 accgtctgcc ggagatgatc aactccgtgc gtggcgaccg cagcccggtt gtagatatca
     1981 gcttcccgga aatcgagaag tttgaccgtc taccggaacc gcgcgccgaa gggccgaccg
     2041 cgtttgtctc catcatggaa ggctgcaata aatattgcac ctactgcgtg gtgccttaca
     2101 cccgtggtga agaggtaagc cgtccgtccg acgatattct gtttgagatt gcccagcttg
     2161 cggctcaggg cgtgcgtgaa gtcaacctgc tcggtcagaa cgtgaacgcc tggcgtggtg
     2221 aaaactacga cggcaccacc ggatcgtttg ccgatctgct gcgtctggtt gctgcgatcg
     2281 acgggatcga tcgtattcgc tttaccacca gccatccgat cgaattcacc gacgatatca
     2341 tcgaagtgta tcgcgacacg ccggagctgg tgagcttcct gcatctgccg gtacagagcg
     2401 gttccgatcg cattctgaac ctgatgggcc gtacccatac ggcgctggag tacaaagcga
     2461 tcatccgtaa actgcgtgcg gcgcgtccag atattcagat cagttctgat ttcatcgttg
     2521 gcttccctgg cgaaaccacc gaagacttcg agaaaacgat gaagctgatt gccgacgtca
     2581 atttcgacat gagctacagc tttatcttct ctgcacgtcc gggtacacca gccgccgata
     2641 tggttgatga tgttccggaa gaagagaaga agcagcgtct gtatattctg caagagcgca
     2701 ttaatcagca agcgatggcg tggagccgcc ggatgctcgg caccacccag cgtattctgg
     2761 tagaaggtac atcgcgtaag agcatcatgg agctttccgg gcgtacggaa aataaccgcg
     2821 tggtcaactt cgaaggcacg ccggatatga tcggtaaatt cgtcgatgta gaaattaccg
     2881 acgtctaccc gaactctctg cgcggtaaag tggtgcgtac tgaagatgaa atgggtctgc
     2941 gcgtggcaga aacaccggaa tcagtgattg cccgtacccg caaagaaaac gaccttggcg
     3001 tgggttatta tcagccgtaa ttctcaggcc tgccgttccg gtgggccttg ttttttctct
     3061 ctttatcccc atctttattg caatgcttgc gcctttttcc tgtggcgtga ataatttcct
     3121 tataggccgg tgaatgttca gcttccggcg gcatacagat aagaggaacg gtttgaacat
     3181 agacactcgc gaaatcaccc tggagccagc agacaatgcg cgtctgttga gcctgtgcgg
     3241 cccgtttgat gacaacatca agcagctcga acgccgtctc ggcatcgaga tcaatcgccg
     3301 cgataaccac tttaaactga ccggccgtcc gatttgcgtc accgctgcgg cagacattct
     3361 gcgtagcctg tatgtcgata ctgccccgat gcgcggtcag attcaggata tcgaaccgga
     3421 acagatccac cttgcgatta aagaagcgcg ggtactggag caaagcgcgg agagcgtgcc
     3481 ggagtacggc aaagcggtca atatcaaaac caaacgcggc gtaattaagc cgcgcacgcc
     3541 aaaccaggcg cagtacatcg ccaatattct cgaccatgac attaccttcg gcgttggccc
     3601 ggcgggtacg ggtaaaacct acctggcagt ggctgcggca gttgatgccc tggagcgtca
     3661 ggaaattcgc cgtattctgc tgactcgtcc ggcagtagaa gccggtgaga aactgggctt
     3721 cctgcctggc gatttaagcc agaaagtaga cccgtatctg cgcccgctgt acgacgcgct
     3781 gtttgaaatg ctgggctttg agaaagtcga gaaactgatt gagcgcaacg ttattgaagt
     3841 cgcaccgctg gcctatatgc gtggtcgtac gctgaacgac gcgtttatca ttctcgatga
     3901 gagccagaac accaccatcg aacagatgaa gatgttcctg acccgtatcg gttttaactc
     3961 aaaagcggtt atcaccggcg acgtcacaca gatcgacctg ccgcgtaata ctaaatcagg
     4021 cttacgtcac gccatcgaag tgctggccga tgtcgaagag atcagcttta acttcttcca
     4081 cagcgaagac gtggttcgtc accctgtggt ggcgcgtatc gttaacgcct atgaagcctg
     4141 ggaagaagcc gaacaaaaac gaaaagcggc gctggcagca gaacgcaagc gcgaagaaca
     4201 ggaacaaaaa tgagtcaggt gatcctcgat ttacaactgg catgtgaaga taattccggg
     4261 ttaccggaag agagccagtt tcagacatgg ctgaatgcgg tgatcccgca gtttcaggaa
     4321 gaatcggaag tgacgattcg cgtggtcgat accgccgaaa gccacagtct gaatctgacc
     4381 tatcgcggta aggataagcc gaccaacgtg ctctccttcc cgtttgaagt gccgcctggc
     4441 atggaaatgt cgctactggg cgatctggtt atctgccgtc aggtggttga gaaggaagct
     4501 caggagcaag gcaaaccact ggaggcgcac tgggcacata tggtggtgca cggcagtctg
     4561 catttgttag gttacgatca catcgaagat gacgaagcag aagaaatgga agccctcgaa
     4621 acagagatta tgcttgctct gggctatgag gatccgtaca ttgccgagaa agaataattt
     4681 gccaggcatt tgactggcag acgtccccgc cgttggtgat taacgacggc gttttgatta
     4741 actaacatga gaacccatac gacgccatga gcgacgacaa ttcacacagt agtgacacga
     4801 taagcaacaa gaagggattt ttctccctgt tactcagcca acttttccac ggtgaaccga
     4861 aaaaccgtga cgaactgctg gcgctgatcc gtgattccgg gcagaacgac cttatcgacg
     4921 aagatacgcg cgatatgctc gaaggggtga tggacatcgc agaccaacgc gttcgcgaca
     4981 tcatgatccc ccgctcccag atgattaccc tgaaacgcaa ccagacgctg gacgaatgtc
     5041 ttgatgtcat catcgagtcc gcccactcac gtttcccggt gattagcgaa gacaaagatc
     5101 acattgaagg gattctgatg gcgaaagact tgctgccgtt tatgcgcagc gatgctgaag
     5161 ccttcagcat ggacaaagtg ttacgtcagg cggttgtcgt tcctgaaagt aagcgcgtag
     5221 accggatgct gaaagagttt cgctctcagc gttaccacat ggcgatcgtt attgacgaat
     5281 tcggtggggt ttccggtctg gtgaccattg aagacatcct ggaactgatt gttggtgaga
     5341 ttgaagacga gtatgacgaa gaagatgata tcgacttccg tcagctgagt cgtcatacct
     5401 ggaccgtacg cgcactggct tccattgaag acttcaacga agcgttcggc acccacttta
     5461 gcgatgaaga agtcgacact atcggtggtc tggtgatgca ggcatttggg catcttccgg
     5521 cgcgtggcga aactatcgac atcgacggtt accagttcaa agtggcgatg gccgacagtc
     5581 ggcgtattat tcaggttcat gtcaaaatcc cggatgactc accccagccg aagctggatg
     5641 aataaaaccg aaactggata gataactaca tggcttttgc ctcattaatt gaacgccagc
     5701 gcattcgcct gctgctggcg ttattattcg gtgcctgcgg aacgctggcc ttctctcctt
     5761 acgacgtctg gcctgcggcg attatttcgc tgatggggct tcaggcgttg acctttaacc
     5821 gccgtccact ccagtctgcc gctattggct tttgctgggg atttggcctc tttggcagcg
     5881 gtattaactg ggtctatgtc agcatcgcga cctttggcgg aatgcctggc ccggttaaca
     5941 tcttcctggt ggtgctgctg gcggcgtatt tgtcgctgta taccggactg tttgctggcg
     6001 tgctgtcgcg tctgtggccg aaaaccacct ggctgcgcgt agcgattgcc gcccctgccc
     6061 tctggcaagt gaccgagttt ctgcgcggtt gggtactgac cggcttcccg tggttacagt
     6121 tcggctatag ccagattgat ggcccgttaa aagggctggc accgataatg ggcgtggaag
     6181 ccattaactt cctgctgatg atggttagtg gcctgctggc actggcgttg gtcaaacgca
     6241 actggcgtcc gctggtggtg gccgtcgtgc tgtttgccct tcccttcccg ctgcgttaca
     6301 tccagtggtt taccccacaa ccggagaaaa ccattcaggt ttcgatggtt cagggcgata
     6361 ttccgcaatc gctgaaatgg gacgaaggcc agcttcttaa tacgctgaag atttactaca
     6421 acgcaacggc accgctgatg ggcaaatcat cgttgattat ctggccggag tcggcgataa
     6481 ccgatctgga aattaatcag caaccgttcc tcaaagcact ggacggtgag ttgcgtgata
     6541 aaggtagctc gctggtaacc gggattgtcg acgcgcgtct caataagcag aaccgctacg
     6601 atacctacaa caccatcatc acgctgggta aaggtgcgcc gtacagctac gaatcagccg
     6661 atcgctataa caaaaaccat ctggtgccgt ttggcgagtt tgtcccgctg gagtcgattc
     6721 tgcgtccgtt agcaccgttc tttgatctgc cgatgtcgtc gttcagccgt gggccatata
     6781 tccagccgcc gctgtcggca aatggtattg agcttactgc ggctatttgc tacgagatca
     6841 ttctcggcga gcaagtgcgc gataacttcc gcccggatac cgactatctg ctgactatct
     6901 ccaacgatgc gtggtttggt aaatctattg gtccatggca acacttccag atggcgcgaa
     6961 tgcgtgcgct ggagctggcg cgcccactgt tgcgcagcac caacaacggc attacggcgg
     7021 tgattggccc gcagggtgag attcaggcga tgatcccgca gttcacccgc gaggtgttaa
     7081 ccactaacgt gacgccgacc accggactca caccatacgc acgtaccggc aactggccgc
     7141 tgtgggtgct gacggcattg tttggttttg ctgctgtgtt gatgagtctg cgtcagcgac
     7201 gtaaataatc ccttcttatc gtgccggaat acatcccata tttcggcacg ctcaccggat
     7261 gcggcatcag tgcattatcc ggataacaat attctcctat ccaactttgg cacatctatt
     7321 gctttgttat acaaggcaaa ccctgaatca gcatcagtac aacctagttg caccacagta
     7381 atccagcggt agcactaaaa gagtgcattt taagaatttt gcttcggaat ggtgcggcgc
     7441 atctcgcaaa aacaaacaat aaaacagcaa tatctttaca tttagccaaa ctaaatgtta
     7501 cctaacaggc acaacactgc acaataaagt tgcagacgat aacaacacaa acactcacaa
     7561 cgggtatcca tgcgttctta acgcagaaga taaaggagtt ggatatgcaa ttacgtaaac
     7621 ctgccacagc aatcctcgcc ctggcgcttt ccgcaggact ggcacaggca gatgacgccg
     7681 ccccggcagc gggcagtact ctggacaaaa tcgccaaaaa cggtgtgatt gtcgtcggtc
     7741 accgtgaatc ttcagtgcct ttctcttatt acgacaatca gcaaaaagtg gtgggttact
     7801 cgcaggatta ctccaacgcc attgttgaag cagtgaaaaa gaaactcaac aaaccggact
     7861 tgcaggtaaa actgattccg attacctcac aaaaccgtat tccactgctg caaaacggca
     7921 ctttcgattt tgaatgtggt tctaccacca acaacgtcga acgccaaaaa caggcggctt
     7981 tctctgacac tattttcgtg gtcggtacgc gcctgttgac caaaaagggt ggcgatatca
     8041 aagattttgc caacctgaaa gacaaagccg tagtcgtcac ttccggcact acctctgaag
     8101 ttttgctcaa caaactgaat gaagagcaaa aaatgaatat gcgcatcatc agcgccaaag
     8161 atcacggtga ctctttccgc accctggaaa gcggtcgtgc cgttgccttt atgatggatg
     8221 acgctctgct ggccggtgaa cgtgcgaaag cgaagaaacc agacaactgg gaaatcgtcg
     8281 gcaagccgca gtctcaggag gcctacggtt gtatgttgcg taaagatgat ccgcagttca
     8341 aaaagctgat ggatgacacc atcgctcagg tgcagacctc cggtgaagcg gaaaaatggt
     8401 ttgataagtg gttcaaaaat ccaattccgc cgaaaaacct gaacatgaat ttcgaactgt
     8461 cagacgaaat gaaagcactg ttcaaagaac cgaatgacaa ggcactgaac taattacaag
     8521 aaccaggggc ggaaattcca gccctctcga ttgttacgta gcacggacag actatacgcc
     8581 tgatggtcgt tccccatcgg gcctgaaaac cgcaatacgc tgggtaacaa tcttcgaggg
     8641 tagcagttaa cgctgctacc ctcttttttc tggagtagat ttatgtctat agactggaac
     8701 tggggtattt ttttacaaca agccccgttc ggcaacacca cctatcttgg ttggatctgg
     8761 agtggttttc aggtgacgat cgctttgtcg atctgcgcct ggattatcgc tttcctcgtc
     8821 ggttcatttt tcggcatttt acgtaccgtt ccaaaccgtt ttctctctgg tctgggtacg
     8881 ttgtatgtcg aactgttccg caacgtgccg ttgattgtgc aattctttac ctggtatctg
     8941 gtgatcccgg agctgctgcc ggagaaaatc ggcatgtggt ttaaggccga gctggatccc
     9001 aatattcagt ttttcctttc atccatgctc tgcctggggc tgtttaccgc cgcccgtgtt
     9061 tgcgaacagg tacgcgccgc gattcagtcg ctgccgcgag ggcaaaaaaa tgccgcgctg
     9121 gcgatgggcc tgacgctacc gcaggcttat cgatacgtac tgctgcctaa tgcttatcgc
     9181 gttatcgtcc cgccgatgac ctcagagatg atgaacctgg tgaaaaactc cgccatcgcc
     9241 tcgactatcg gtctggtgga tatggcggcg caggcgggta aattgctcga ttactcagcc
     9301 catgcctggg agtcgtttac cgccattacg ctggcgtatg tgttgattaa cgcttttatc
     9361 atgctggtga tgacgctggt tgaacgtaaa gttcgcctgc ctggcaacat ggggggcaaa
     9421 taatgtacga gtttgactgg agttccattg tcccttccct gccatatctg ctcgacgggc
     9481 tggtgatcac cctgaaaatc accgtcacgg cggtagtgat tggtattttg tggggcacga
     9541 tgctggcggt gatgcgttta tccagctttg cgcccgtggc gtggtttgcc aaagcctacg
     9601 ttaacgtatt ccgctcgatt cctttagtta tggttttgct gtggttttac ctgatcgtgc
     9661 cgggttttct gcaaaacgtg ctgggattat cgccaaaaaa tgatatccgt ttaatttcgg
     9721 cgatggtggc gttttcgatg tttgaagcgg cctactattc agagattatc cgtgctggta
     9781 ttcaaagtat ttctcgtggt caatcgagcg ccgcgctggc gttgggaatg actcactggc
     9841 agtcgatgaa actgattatt ctgccgcagg cgttccgcgc gatggtgccg ctgctgctca
     9901 ctcagggcat cgtactgttc caggatacct cactggtgta tgtgttatcc ctggccgatt
     9961 tcttccgtac cgcctcaacc attggtgagc gtgatggtac gcaggttgag atgatcctgt
    10021 ttgccggatt tgtttatttc gttattagtc ttagcgcgtc gttgttggtc agctacttga
    10081 aaagaaggac agcataatga ttaccctgaa aaatgtttca aaatggtatg gtcactttca
    10141 ggtgctgacc gactgctcaa ccgaagtgaa aaaaggcgaa gtggtggtgg tttgcggccc
    10201 gtctggttcc ggcaaatcaa cgctgattaa aaccgtcaac ggcctcgaac cggtgcagca
    10261 aggtgaaatc accgtcgatg gtatcgtggt taacgacaag aaaaccgatc tggcaaagct
    10321 gcgttcccgc gtcgggatgg tattccagca tttcgagctg ttccctcatc tgtcgattat
    10381 cgaaaacctg accctggcgc aggtgaaagt gcttaaacgc gataaagcgc cggctcgtga
    10441 aaaagccctg aaactgctgg agcgtgtcgg gctttctgct cacgccaata agtttccggc
    10501 gcagctttcc ggcggtcagc agcagcgtgt ggcaatcgct cgcgcgttgt gtatggatcc
    10561 tattgcgatg ctgtttgacg aaccgacatc ggcgctggat ccggagatga tcaacgaagt
    10621 actggacgtg atggtggaac tggcgaacga aggaatgacc atgatggtgg tgacccacga
    10681 aatgggcttt gcccgtaaag tggcgaatcg ggtgatcttt atggacgagg gtaaaattgt
    10741 cgaagactcg ccgaaagacg ctttcttcga tgatccgaaa tcggaccgcg caaaagactt
    10801 cctcgcgaaa atcctgcatt aatcactctg gcgcgcatac ccaattgcgc gccatctcac
    10861 gctttatcgt ttcgcccctc gtatctgtta catcctggcg ttacccttgt cgcaaagaag
    10921 cacacaacaa ggagcaacaa tggcactgcc aattctgtta gattgcgacc caggtcatga
    10981 cgacgctatc gcaatagttc tcgccctcgc ctcaccagag cttgatgtca aagcaattac
    11041 gtcttccgcc ggaaaccaga caccagaaaa aaccttacgc aatgttctgc gtatgctgac
    11101 cttgcttaat cgcaccgata ttccggtagc aggcggcgcg gtaaaaccgt taatgcgtga
    11161 gttgattatc gcggacaatg tgcacggcga aagcggtctc gacggcccgg cattaccgga
    11221 accgacattc gcaccgcaaa actgtacggc ggtagagctg atggcgaaaa cgctgcgtga
    11281 aagtgcggaa cctgtcacca ttgtgtctac cggaccgcaa actaacgttg ccttgctgct
    11341 caatagccat ccggaactgc atagcaaaat tgcccgtatc gtgattatgg gtggcgctat
    11401 ggggctgggt aactggacgc ctgcggctga atttaatatt tacgttgacc cggaagcggc
    11461 agaaattgtc ttccagtcag ggatcccggt ggtgatggcc ggtctggatg ttactcataa
    11521 agcacaaatc cacgttgaag acaccgagcg tttccgcgcg attggtaacc ctgtttcaac
    11581 cattgttgcc gaactgctgg atttcttcct cgaatatcat aaagacgaaa aatggggctt
    11641 tgtcggcgca ccactgcatg acccatgcac catcgcctgg ctgttgaaac cggagttatt
    11701 tacctctgtt gagcgctggg ttggcgtgga aacacagggg aaatataccc agggtatgac
    11761 ggttgttgat tattattatc tgacaggcaa taaaccgaat gccaccgtaa tggtcgatgt
    11821 tgatcgtcag ggctttgttg atttactggc tgatcgtctg aaattttacg cttaacacac
    11881 gtcattgatt aagatcacca cgcgttacct gggtggtctt aatctgttta tctctttttc
    11941 tttcaagata taaatgcaat ggataatgca gaactcgcca ttggtatcga tctcggtact
    12001 accaatagtt taattgccgt ctggaaagac ggtgccgcgc aattaattcc aaataagttc
    12061 ggtgaatatt taacaccatc cataattagc atggatgaaa ataatcatat tttagtcgga
    12121 aaaccggctg tatcacggcg tacttcgcat ccggataaaa cggcagcgtt atttaaacgt
    12181 gcaatgggca gtaataccaa ctggcggtta ggcagcgaca catttaacgc gccagaactg
    12241 tcctctttgg tattacgctc attaaaagaa gatgccgaag aatttctgca acgtccgatt
    12301 aaagatgtgg tgatctccgt tccggcttat ttcagcgatg aacaacgcaa gcatacccgt
    12361 ttagcagcgg agttagccgg gttaaatgcg gtacgcttaa ttaatgaacc cacagcagct
    12421 gcgatggcgt atggcctgca tacccaacaa aatacccgtt cgctggtgtt tgatctcggt
    12481 ggcggcacgt ttgacgttac ggtgcttgag tacgccacgc cggtgattga agttcacgcc
    12541 tccgctggcg acaactttct tggtggcgaa gattttaccc atatgctggt cgatgaggtt
    12601 ttaaaacgcg cggatgtcgc caggaccacg cttaacgaga gtgaactggc agccttgtac
    12661 gcctgtgtgg aagcggcaaa atgtagcaat caatcgccat tgcacattcg ctggcagtat
    12721 caggaagaaa cgcgggaatg cgaattttac gagaacgaac tggaagattt gtggttgccg
    12781 ctgctcaatc gcttgcgagt gccgattgaa caggcgttgc gcgatgcgcg tctgaagccg
    12841 agtcaaatcg acagtctggt gctggttggc ggcgcgtcac aaatgccgct ggtgcagcga
    12901 atcgccgtgc gtctgtttgg caaattaccg tatcaaagtt acgatccgag caccattgtc
    12961 gcgctgggcg cagcaatcca ggccgcctgc cgcttacgca gtgaagatat tgaagaggta
    13021 atcctcactg atatttgccc ttactcgttg ggcgttgaag ttaaccgcca gggcgtttcc
    13081 ggcattttct cgccgattat tgaacgaaac accactgtgc ccgtgtcgcg tgtagaaact
    13141 tattcaacca tgcacccgga acaggattca attacggtta acgtctatca gggagaaaac
    13201 cacaaagtta aaaacaacat tctggtggaa tccttcgatg tgccgttgaa gaaaaccggg
    13261 gcttatcagt cgattgatat tcgctttagt tatgatatca acgggttgct tgaagttgac
    13321 gtgcttctgg aagacggcag cgttaagtcc agagtgatta accacagccc ggtaacattg
    13381 agcgcgcagc agattgaaga gagtcggacg cggttatccg cattgaaaat ttatccgcgc
    13441 gatatgctca tcaatcgcac ctttaaagcc aaactggaag agttgtgggc gcgggcgctg
    13501 ggtgacgagc gagaagagat cggccgggtg atcaccgatt ttgatgcggc gttgcagtca
    13561 aacgatatgg cccgcgtgga tgaagttcgg cggcgggcga gcgattattt agccattgag
    13621 atcccataaa cacggctgcc ggatgcggcg taaacgctgc atccggcatc ggcgcaaaaa
    13681 acacatcgtc agctaaacaa catcgcgatt ttgccgagag cataacctat caccagcacc
    13741 gttaaactga ttttgataat gctggtaatg ctctgtggtt tttcaccctc atcatttttt
    13801 tcttcatgat tttcaggtgt tggctcatcg acatcttcat cctccggctc gagtttcact
    13861 ttcgtcaaaa gcatccgggt gacaatggcc tctaatggat gagcatctcc gccttccagc
    13921 cttgtattaa gacgggccag catctcttgt ttcggaaacg cttcaagtac tacctgttcc
    13981 gctacccgat acaaatccag gaacggtgaa tcttgctctg tctcgctacc gactctcgat
    14041 ttccaccacg cccatgcttt gcgcttgaag aataacgact caataaacga ttgacctaac
    14101 ggcgataatt ttccgctatg taaaatctcc gcccataaca gccgcgtccg ggcgctctca
    14161 ccaggaacat atttcagcgg ttgaccttgc gcatctacca tgctccgcgc ttcgataacc
    14221 atcactaata acgcgaaata atccgggcaa tgacgcttgc tccactgcaa caacaaatta
    14281 tcagcttgtg tagatgggta actttcccag tacgcgcaga gatcggcaag caggctttcc
    14341 ccctcgccgc agtacaaacg ttgtgcacac aagtaatacc gggcatcttc gctttctggt
    14401 tcttccgttt gccactgttg agcgacagga atgagttccg ccatacctgt ttgcaccgag
    14461 ctgtaccagc gcaacagttt gcgatgtaac tttgcatcat caggaattaa ccacggacct
    14521 tccatcgcca aaaacgcagt gacatagtca ggatggtaac ggcagcaacg ttccagcgcg
    14581 aagtaatact caacagtctg gttctgcaac gcaatgggat attccagaag gctaaggaaa
    14641 tcgaaacaat caccagcctg aatggcctca agaaaagcct ccctttcttc ctcatccatt
    14701 ccttcgctgt cattaaatga atgccagttc aaacgctctg ccagcaaaga agcacaattt
    14761 aatgaaagat atcgcgcttc tatggcgatt gcacacagcg gccagcgtaa ttgatcgaca
    14821 tcctccatgt tccaggtatt taattgctga ataaatttct gccaggcgga aggctgaaaa
    14881 cgatcacttt ctgaatccag taatgtcctg aatgcacgta gtatttcatg ttcagcggca
    14941 gcatcttttt cttcatcatc tgcttcctcg acaggattta ccgccagtcg cagggcctct
    15001 tcataggcct ggcgtaatgc tttaaaccct tgcggatcgg tttcgggatg acacaacggt
    15061 aagcgagcaa gataagcctg gcggataatg tctatttgcg tcgtgctttc aatttcgagg
    15121 atttgccaac atgttttcat aggtcgctca catccttaag cgttaccggg cattcagact
    15181 ggacagttaa tggctgccag ggaagcgtgg catagaaacg atcgcttccc gctgccagct
    15241 cttcgaacat acgactcccg gcgctatcgt atttgtacag ggttagcgcc tcgcgtagcg
    15301 aagtgttgtc ttcgcactga gaagattgcc agtagagacg tcctaacgaa taggcggaaa
    15361 aatagtgcat ccagctgtga tagtaatggt gagctcgtac atagacgcgc gattgcagcc
    15421 ataaactctc ttcttccgtc agccacttgt tgagcacacc gacccgtgac agaaacccca
    15481 ttcgaacata atcccaggct ttgattcccc cttccccaca gcacatagcg gtttgggcaa
    15541 cgaattgggt ataaatcaac cctctctccg agccaccagc aattaatgct ttccactctt
    15601 caggggaaga gcgatgccat gtcagatata agccagctaa atcattggca tgaccatcat
    15661 cagtcatctg ataaatagtc tgaattaaat catcacgatt atttattccc caggatgatg
    15721 agagctcgaa ttcttttatc ccagtataca tttttggcga gtcatgcgcg ggtttgcaac
    15781 cctgattaag tatttccatg ggcgcagaaa gcgcaaaaag aagatattgt tcttccttat
    15841 tcatttgtta ataatccctt aagtgcatta actgactact tttttattat tgatgagtat
    15901 aaacttgacg ctttcaaaat aaaaagaaaa tcgaagcatt cacacatgaa taaaaaatta
    15961 atgtatatat tcgcaatttt tatagttgca gcaattacct gtattagcca acccaagaaa
    16021 acgacgttgc gtgataaagc catggtgaat tatgcctttg attatttaag ctcaccgggc
    16081 agtcttccat tcaccacggc agccacggag ctttccgcga ttcatggtca ctcaacgtcg
    16141 caatatcgcc ttggagaatt ttatcttcat ggtagcgacg gtaaaccact ggattataca
    16201 caggcgagat actggtatga gcaatcagcg gaacaggaaa atccacgcgc gcaaagtaaa
    16261 ctggggtgga tctacctcaa aggtctgggg gtcaaacccg acacccgtaa agcaattctc
    16321 tggtataagg aagcagctga acaagggtat gctcatgctc aatatacttt aggtttgatc
    16381 tacagaaatg gctcaggtat taatgttaac cattatgaat ctcaaaaatg gttaaaactg
    16441 gccgccaaac aacattacaa aaatgcggaa agattacttg ccgggcttcc cgcacattaa
    16501 cgtcgactgt cacccgaaca gatggagtat tttccctatc aaaccagcaa agataaaaat
    16561 atagaaaata attttaatga tgcccagaca gcctggccca ccatcgtcaa cgggcattgg
    16621 ctgcggttgc ggctccggtt caacagtttg cttctcggta aaattcgccg cctgaattaa
    16681 taatcgacga ataattaatg cttccagtgg acaacgattt tctgcatcaa ggcggctcac
    16741 aatcggcatt aatgattctt ctgtaggttg gcaggcctgc actaattgtt tggcaactag
    16801 atataatggc cataaggtat gttctgtatc acgcgtgagt gagatccgcg gcttacgtcc
    16861 tttgtgcaaa accatctcga ccagtgaacg ccccagcgca gagagttttt catcgctgag
    16921 tatttcgtat aaatgaaaac gcgtacgggc gctgtcgccg gggacataaa gtagcggttt
    16981 tccctgatcg ttaaccagat cacgcgcttc aatcatcatc accagtaatg ggtaataatc
    17041 gacccgatgc tgacggcacc attgcaacat taaagcatcc gcctgggtgg agggatactc
    17101 gcgccagtag tcacaaagtt ctgccaacag gctttcgcct tctccacaat agacgcgttg
    17161 cgcgtattca taataaggcg catcttcatt atcaggttca gtttcccgcc atgactgggc
    17221 gtaatccaga agttcgggga tatccaggcg acctgcgcta taccagcgga gtaaatttct
    17281 gtgcagtttt gcatcatcgg ggataatcac tgcgcgatgt tgcgctaaat acaatgtcag
    17341 ccattgtgga tgcgatgacc aaatccgagc gaacatttgg taaaaatcga tggtgtcatt
    17401 ttgcacggca acgggcagat gcagaatggt ctggaagtta aaaacattcc ccttcgcaat
    17461 ggcatataaa aaggattcca gttcttcttc gtctatttcc ccggtatttt cctcctgtaa
    17521 ccaccgcaat ctttctgcta ataacaccac gcactcgaag gataaatggg cagtgttcat
    17581 ggcgattgtg cacagcgacc agcgtaattc atcaatctcc tccatcgagc aataatttaa
    17641 ttgctgaatg aatcgctgcc aggcggaggg cagaaaacgt tcactatcag aggcaagtaa
    17701 cgcacgaaag gcgagcagaa tttcatgttc tgctacctca tattcttctg gttgccaaac
    17761 agatttagca ggcgactgcg caatccgtag cgcctcctca tacgcctgac gaagttgttt
    17821 aaaaccctgc ggatcggttt ctggatgaaa ggacggtaac agcgccagat aagcgcggcg
    17881 gataatatcg acgtcagtcg tttcctctat atcgaggatc ttccagcaat ttttcatagg
    17941 tcgctcatat ccttaagcgt ttccgggcat gcagaatagt aagccaatgg ttgccaggac
    18001 aaggtagggt aatacgcatc atcactggca aataattgat aaaacatatc attgccggaa
    18061 tcgtcgtatt ctttacgcgc taagaattcg cgtaataaag gcagatgatc atcttcggga
    18121 gactgccaat attgccgacc aaaggtataa ccggcaaagt attgccgcca gttactataa
    18181 taacgtagag cccgtagatg aatgcgcgac tggatccata gactttcttc ttcgctcaac
    18241 cagttattaa gtacgcccat tcggcttaaa aaacccatcc ggacataatc ccaggctttg
    18301 attccccctt cgccacagca ttcggcggtg ctggcgacaa attgcgcata agcctgacct
    18361 tgctcattta gttcagcaag atagtcacgc cattcacatg gcgaataacg aaaccagcgg
    18421 tgataaaacc ctgccaaccg agcggcatga ccgttatcga tcattcggtg aattgtgcgc
    18481 agcaggtcat cacggtcatc aattccccat gaggaagaaa ggtcgaaaaa gcatgtacct
    18541 aaatacattt tgggtgatga atgcgaaggt aaacagcatt cattgcgtat ttccatcgga
    18601 gtggaaagtg caaacaatat tttttgcgac tccatgtcca tataatttat ccttaaatat
    18661 tcattaaatg aatattagcc gcattgcgag gctcgtttat ttatactttt ctgacgcgac
    18721 ataatacgca taaaataagg cttacgcaaa aatggaacac ataaaaatat aatatgtttt
    18781 atctgcaacc ataaggaaat gataatgatt ttcacgtcaa gttgctgcga taatttatca
    18841 atagatgaga ttatcgaacg tgctgaaaaa ggcgattgcg aggctcaata tattgttggg
    18901 ttttattata atcgcgatag cgcaattgat tctccggacg acgaaaaagc cttttactgg
    18961 ctgaagctgg ccgctgagca aggtcattgt gaagcacagt attccttagg gcaaaagtat
    19021 accgaggata aaagccgtca taaagataat gagcaagcca tcttctggct gaaaaaagct
    19081 gccctacaag gccatacttt cgcttccaac gcccttggct ggacactgga tcgtggagaa
    19141 gcccccaatt ataaagaagc ggttgtctgg tatcagatag ccgcggagag cggaatgtct
    19201 tatgcgcaaa ataatcttgg gtggatgtac agaaatggca acggagtcgc aaaagactat
    19261 gcgctggcat ttttctggta caaacaagct gcattacaag gccatagtga cgcgcaaaac
    19321 aatctggccg atctttatga agacggaaaa ggcgttgctc aaaacaagac actcgccgca
    19381 ttctggtatt tgaaaagcgc acagcagggt aatcggcacg cccagtttca aattgcatgg
    19441 gattataacg ctggcgaagg ggtggaccag gactataagc aagcgatgta ctggtatctg
    19501 aaggctgccg ctcaggggag cgtcggcgct tacgtcaaca tcggttatat gtataaacac
    19561 ggacaaggcg ttgagaaaga ttatcaggct gcctttgaat ggtttacgaa agccgctgaa
    19621 tgcaatgacg ccactgcctg gtataacctg gccattatgt atcactacgg agaaggaaga
    19681 cctgtcgatc tccgacaggc tctcgacctg tatcgtaaag ttcagtcatc cggaaccaga
    19741 gatgtcagtc aggaaattcg tgagactgaa gatttactgt agagataaaa acaagggccg
    19801 gggaatttca ttcggcccat attctcttta ttgctgtgcg aaatcagact attacggctc
    19861 aaacgggcgt ctctggaact ggtcatgacc acatttcggg catagcgtca gcacttccgg
    19921 tgtgtagatc gggagatgga agtgacattt ctcgcagacc agatttccca gcccgaccac
    19981 ttctccgctg tgataaaccc catgatgatt gaggtcctgg aaaacttcgc gccattcaag
    20041 ctgcgtttta tcggtgatgt ctgccagctc ctgccacaag ctttctttaa tcacccgcat
    20101 aaagacgctg tcagattctt ctttcaggct ctcttcatag ctcatggcga actcttccag
    20161 gtcacgtctg acagctcgcg tcagctcatc gacctcggtt cgcgttaact cccctgtttt
    20221 tattacgcgc tcgcgcgcct gttccaccag tgcgtcgata tcacgttcgc cattgcgcag
    20281 gcgttcgctc agtgacgcaa ccagttcacg gtaatattga gcaaccttgt tcatcgtttc
    20341 atctcccggg tcgttaactg actataataa tagacgttct ttgttccttg ctttgctaat
    20401 acgcccacaa actctgtaaa ttaatgtatg aataatccgg gcatcatttc aacgtcgagt
    20461 gcgcgaaagg ctgttttgac gcggacgttt gggctatgct atgcggatct gaaaaaccac
    20521 ctcaacgcta catttgtagc cgtattgaaa acaggaccac tggctgccat gcaagagcaa
    20581 taccgcccgg aagagataga atccaaagta cagcttcatt gggatgagaa gcgcacattt
    20641 gaagtaaccg aagacgagag caaagagaag tattactgcc tgtctatgct tccctatcct
    20701 tctggtcgac tacacatggg ccacgtacgt aactacacca tcggtgacgt gatcgcccgc
    20761 taccagcgta tgctgggcaa aaacgtcctg cagccgatcg gctgggacgc gtttggtctg
    20821 cctgcggaag gcgcggcggt gaaaaacaac accgctccgg caccgtggac gtacgacaac
    20881 atcgcgtata tgaaaaacca gctcaaaatg ctgggctttg gttatgactg gagccgcgag
    20941 ctggcaacct gtacgccgga atactaccgt tgggaacaga aattcttcac cgagctgtat
    21001 aaaaaaggcc tggtatataa gaagacttct gcggtcaact ggtgcccgaa cgaccagacc
    21061 gtactggcga acgaacaagt tatcgacggc tgctgctggc gctgcgatac caaagttgaa
    21121 cgtaaagaga tcccgcagtg gtttatcaaa atcactgctt acgctgacga gctgctcaac
    21181 gatctggata aactggatca ctggccagac accgttaaaa ccatgcagcg taactggatc
    21241 ggtcgttccg aaggcgtgga gatcaccttc aacgttaacg actatgacaa cacgctgacc
    21301 gtttacacta cccgcccgga cacctttatg ggttgtacct acctggcggt agctgcgggt
    21361 catccgctgg cgcagaaagc ggcggaaaat aatcctgaac tggcggcctt tattgacgaa
    21421 tgccgtaaca ccaaagttgc cgaagctgaa atggcgacga tggagaaaaa aggcgtcgat
    21481 actggcttta aagcggttca cccattaacg ggcgaagaaa ttcccgtttg ggcagcaaac
    21541 ttcgtattga tggagtacgg cacgggcgca gttatggcgg taccggggca cgaccagcgc
    21601 gactacgagt ttgcctctaa atacggcctg aacatcaaac cggttatcct ggcagctgac
    21661 ggctctgagc cagatctttc tcagcaagcc ctgactgaaa aaggcgtgct gttcaactct
    21721 ggcgagttca acggtcttga ccatgaagcg gccttcaacg ccatcgccga taaactgact
    21781 gcgatgggcg ttggcgagcg taaagtgaac taccgcctgc gcgactgggg tgtttcccgt
    21841 cagcgttact ggggcgcgcc gattccgatg gtgacgctgg aagacggtac cgtaatgccg
    21901 accccggacg accagctgcc ggtgatcctg ccggaagatg tggtaatgga cggcattacc
    21961 agcccgatta aagcagatcc ggagtgggcg aaaactaccg ttaacggtat gccagcactg
    22021 cgtgaaaccg acactttcga cacctttatg gagtcctcct ggtactatgc gcgctacact
    22081 tgcccgcagt acaaagaagg tatgctggat tccgaagcgg ctaactactg gctgccggtg
    22141 gatatctaca ttggtggtat tgaacacgcc attatgcacc tgctctactt ccgcttcttc
    22201 cacaaactga tgcgtgatgc aggcatggtg aactctgacg aaccagcgaa acagttgctg
    22261 tgtcagggta tggtgctggc agatgccttc tactatgttg gcgaaaacgg cgaacgtaac
    22321 tgggtttccc cggttgatgc tatcgttgaa cgtgacgaga aaggccgtat cgtgaaagcg
    22381 aaagatgcgg caggccatga actggtttat accggcatga gcaaaatgtc caagtcgaag
    22441 aacaacggta tcgacccgca ggtgatggtt gaacgttacg gcgcggacac cgttcgtctg
    22501 tttatgatgt ttgcttctcc ggctgatatg actctcgaat ggcaggaatc cggtgtggaa
    22561 ggggctaacc gcttcctgaa acgtgtctgg aaactggttt acgagcacac agcaaaaggt
    22621 gatgttgcgg cactgaacgt tgatgcgctg actgaaaatc agaaagcgct gcgtcgcgat
    22681 gtgcataaaa cgatcgctaa agtgaccgat gatatcggcc gtcgtcagac cttcaacacc
    22741 gcaattgcgg cgattatgga gctgatgaac aaactggcga aagcaccaac cgatggcgag
    22801 caggatcgcg ctctgatgca ggaagcactg ctggccgttg tccgtatgct taacccgttc
    22861 accccgcaca tctgcttcac gctgtggcag gaactgaaag gcgaaggcga tatcgacaac
    22921 gcgccgtggc cggttgctga cgaaaaagcg atggtggaag actccacgct ggtcgtggtg
    22981 caggttaacg gtaaagtccg tgccaaaatc accgttccgg tggacgcaac ggaagaacag
    23041 gttcgcgaac gtgctggcca ggaacatctg gtagcaaaat atcttgatgg cgttactgta
    23101 cgtaaagtga tttacgtacc aggtaaactc ctcaatctgg tcgttggcta agcgcgggag
    23161 gaagcgtgcg atatctggca acattgttgt tatctctggc ggtgttaatc accgccgggt
    23221 gtggctggca tctgcgtgat accacgcagg ttccttccac tatgaaggtc atgatcctgg
    23281 actcaggcga tccgaacggg ccattaagcc gtgcggtgcg taaccagtta cgtctgaatg
    23341 gtgtcgagtt gcttgataaa gaaaccacgc gtaaggacgt tccatccttg cgtttgggta
    23401 aagtgagcat cgcgaaagat accgcatcgg tattccgtaa cggtcaaaca gcagagtatc
    23461 agatgatcat gacggttaat gcgaccgtgt tgatccccgg ccgtgatatc tacccgatta
    23521 gcgccaaagt cttccgttcg ttcttcgata acccgcaaat ggcgttagcg aaagataacg
    23581 aacaagacat gatcgtaaaa gagatgtacg accgtgctgc cgaacagctg attcgtaagc
    23641 tgccaagcat ccgtgctgcg gatattcgtt ccgacgaaga acagacgtcg accacaacgg
    23701 atactccggc aacgcctgca cgcgtctcca ccacgctggg taactgatga ttcggttgta
    23761 cccggaacaa ctccgcgcgc agctcaatga agggctgcgc gcggcgtatc ttttacttgg
    23821 taacgatcct ctgttattgc aggaaagcca ggacgctgtt cgtcaggtag ctgcggcaca
    23881 aggattcgaa gaacaccaca ctttttccat tgatcccaac actgactgga atgcgatctt
    23941 ttcgttatgc caggctatga gtctgtttgc aagtcgacaa acgctattgc tgttgttacc
    24001 agaaaacgga ccgaatgcgg cgatcaatga gcaacttctc acactcaccg gacttctgca
    24061 tgacgacctg ctgttgatcg tccgcggtaa taaattaagc aaagcgcaag aaaatgccgc
    24121 ctggtttact gcgcttgcga atcgcagcgt gcaggtgacc tgtcagacac cggagcaggc
    24181 tcagcttccc cgctgggttg ctgcgcgcgc aaaacagctc aacttagaac tggatgacgc
    24241 ggcaaatcag gtgctctgct actgttatga aggtaacctg ctggcgctgg ctcaggcact
    24301 ggagcgttta tcgctgctct ggccagacgg caaattgaca ttaccgcgcg ttgaacaggc
    24361 ggtgaatgat gccgcgcatt tcaccccttt tcattgggtt gatgctttgt tgatgggaaa
    24421 aagtaagcgc gcattgcata ttcttcagca actgcgtctg gaaggcagcg aaccggttat
    24481 tttgttgcgc acattacaac gtgaactgtt gttactggtt aacctgaaac gccagtctgc
    24541 ccatacgcca ctgcgtgcgt tgtttgataa gcatcgggta tggcagaacc gccggggcat
    24601 gatgggcgag gcgttaaatc gcttaagtca gacgcagtta cgtcaggccg tgcaactcct
    24661 gacacgaacg gaactcaccc tcaaacaaga ttacggtcag tcagtgtggg cagagctgga
    24721 agggttatct cttctgttgt gccataaacc cctggcggac gtatttatcg acggttgata
    24781 tgaaatcttt acaggctctg tttggcggca cctttgatcc ggtgcactat ggtcatctaa
    24841 aacccgtgga aacgctggcg aatttgattg gtctgacgcg ggtcacaatc atccctaata
    24901 atgttcctcc gcatcgtccc cagccggaag cgaacagcgt gcagcgtaaa cacatgcttg
    24961 aactggcgat tgccgacaag ccattattta ctcttgatga acgcgagcta aagcgcaatg
    25021 ccccctctta cactgcgcaa acactgaaag agtggcggca ggaacaagga ccggacgtgc
    25081 cgctggcgtt tattattggt caggattcac tgctgacctt tccgacctgg tacgaatacg
    25141 aaacgatact cgacaatgca catttgatcg tctgtcggcg tccaggttac ccacttgaaa
    25201 tggcgcaacc gcaataccag caatggctgg aagatcattt gacacataac ccggaagatc
    25261 ttcaccttca gcctgccggt aaaatttatc tggctgaaac gccgtggttt aacatctcgg
    25321 cgaccatcat ccgcgaacgt ttgcaaaacg gtgaatcatg tgaggattta ttgccggaac
    25381 cggtactgac ttacattaac caacaaggct tgtatcgctg atacctgtcg ttacggaggg
    25441 catgatgcga ctgtggttaa ttcgtcatgg tgaaacgcaa gcgaatatcg atggtcttta
    25501 cagcggtcat gcgcccaccc ccctgaccgc gcgcggtatt gagcaagcgc aaaatctgca
    25561 tacgctgcta catggtgttt cctttgatct ggttttatgc agtgaactgg aacgggcaca
    25621 gcataccgcg cgactggttc tcagtgaccg ccagctcccc gtgcaaatca tacctgaact
    25681 caacgaaatg ttttttggcg actgggagat gcgacatcat cgcgacctca tgcaagaaga
    25741 tgccgaaaac tatagcgcgt ggtgcaatga ctggcagcat gcaatcccca cgaacggtga
    25801 aggatttcag gcattttcgc aacgtgtgga acgctttatc gcaaggctta gtgaatttca
    25861 gcactatcag aatattttag tcgtcagcca tcagggtgta ctgagtctgt taatcgcccg
    25921 tttaattggc atccctgccg aggctatgtg gcattttcgc gttgaccagg ggtgttggag
    25981 cgccattgat atcaaccaaa aattcgcgac gctacgcgtc ctcaatagcc gtgccatcgg
    26041 ggtcgagaat gcatgacttt tctgtttttt tacgggtaag ccgcaacgac cattgacaga
    26101 cccgggcagg ctgatattct ccgcagccag actttttccg ccagacacga ctttgtagaa
    26161 attgttttac aaaaatggcg atgcaatctg cggcgcgggg tgggatgata gcccactttc
    26221 gaaagccgat tcggcgacaa ttgtcccgaa atcgcctctg gttcaggtat actgacagac
    26281 catttttatc tatttgattc acccaggggg aaaacttgca gggtaaagca ctccaggatt
    26341 ttgttatcga caaaattgat gacctcaaag gtcaggacat catcgcctta gacgttcagg
    26401 gcaaatccag catcaccgac tgcatgatca tctgtacggg tacgtccagc cgtcatgtta
    26461 tgtccattgc tgaccacgtt gtgcaggagt ctcgcgcagc gggcctgtta ccgctcggcg
    26521 tagaaggtga aaacagcgcc gactggattg tcgtggattt gggcgatgtg attgtccatg
    26581 tcatgcagga agagagccgt cgcctgtatg aactggaaaa actctggagt taatgcgtga
    26641 agctgcaact tgtcgccgtg ggaacgaaaa tgccggactg ggtacaaacc ggttttaccg
    26701 agtacctgcg tcgttttccg aaagatatgc ccttcgagct gattgaaatt ccggccggaa
    26761 aacgcggcaa gaatgcggac atcaagcgca tactcgacaa agagggtgag cagatgttgg
    26821 cggccgcagg caaaaaccgc attgtcaccc tcgatattcc aggcaagccc tgggatacgc
    26881 cgcagttagc cgctgagctg gaacgctgga agctggatgg tcgcgacgtc agtctactga
    26941 ttggcgggcc tgaagggttg tcgcctgcct gtaaagcggc ggctgagcag agctggtcgc
    27001 tgtcggcgct taccctcccc catccgctgg ttcgcgtgct ggtcgcagag agtctgtacc
    27061 gggcgtggag catcaccacc aaccatcctt atcaccgtga gtgataaggg agctttgagt
    27121 agaaaacgca gcggatgaaa ctacagaact cttttcgcga ctatacggca gagtccgcgc
    27181 tgtttgtgcg ccgggcgctg gtcgcctttt tggggatttt gctgctgacc ggcgtgctta
    27241 tcgccaacct gtataatctg caaattgttc gctttaccga ctaccagacc cgctctaatg
    27301 aaaaccgcat taagctggtg cctatcgcgc ccagccgcgg cattatctac gatcgtaacg
    27361 gtatccctct ggccctcaac cgcactatct accagataga aatgatgccg gagaaagtcg
    27421 ataacgtgca gcaaacgctg gacgctttgc gcagcgtggt agatctgacc gatgacgata
    27481 ttgctgcatt ccgaaaagag cgcgcacgtt cacaccgttt cacctctatt ccggtgaaaa
    27541 ctaacctgac cgaagtacaa gtagctcgct ttgccgtcaa tcagtaccgt tttccgggtg
    27601 tcgaagttaa aggctataaa cgtcgttact atccttacgg ttcggcgttg acccacgtca
    27661 tcggctatgt gtcgaaaatc aacgataaag acgtcgaacg cctgaataat gacggcaaac
    27721 tggccaacta tgcggcaacg catgatatcg gtaagctggg cattgagcgt tactatgaag
    27781 atgtgctgca cggtcagacc ggttatgaag aggttgaagt taacaaccgt gggcgtgtta
    27841 ttcgccagtt aaaagaagta ccaccgcaag ccggacacga tatttacctg acgctggatc
    27901 tcaaactcca gcaatatatt gaaacgctgc tggcgggtag ccgcgcagct gtggtagtca
    27961 ccgatccgcg tacaggtggg gtgctggcgc tggtttccac gcctagttat gacccaaact
    28021 tgtttgttga cggtatctcc agcaaagatt attccgcctt gttgaacgat ccgaatacac
    28081 cgctggtgaa ccgcgccaca cagggggttt atcctcccgc gtctacagtt aaaccctatg
    28141 tggcggtttc ggcattgagc gccggggtga tcacgcgcaa tacgacgctg tttgacccag
    28201 gctggtggca actgccaggt tcggaaaaac gttatcgtga ctggaaaaaa tggggccacg
    28261 ggcgtctgaa tgtcacaaga tcgctggaag aatctgcgga taccttcttc tatcaggtgg
    28321 cctacgatat ggggatcgat cgcctctccg aatggatggg taaattcggt tatggtcatt
    28381 acaccggtat cgacctggcg gaagaacgtt ccggcaacat gcctacccgc gaatggaaac
    28441 agaaacgctt taaaaaaccg tggtatcagg gtgacaccat tccggttggt atcggtcagg
    28501 gttactggac agcgacccca atccagatga gtaaggcact gatgatcctg attaatgacg
    28561 gtatcgtgaa ggttcctcat ttgctgatga gcaccgccga agacggcaaa caggtgccat
    28621 gggtacagcc gcatgaaccg cccgtcggcg atattcattc cggttactgg gagctggcga
    28681 aagacggtat gtacggtgtt gctaaccgcc ctaacggtac ggcgcataaa tactttgcta
    28741 gcgcaccgta caaaattgcg gcgaaatccg gtaccgctca ggtcttcggt ctgaaagcga
    28801 acgaaaccta taatgcgcac aaaattgccg agcgtttacg tgaccacaaa ctgatgaccg
    28861 cctttgcgcc atacaacaat ccgcaagtgg ctgtcgccat gattctggag aacggtggtg
    28921 cgggtccggc ggttggtaca ctgatgcgcc agatcctcga ccacattatg ctgggtgata
    28981 acaacaccga tctgcctgcg gaaaatccag cggttgccgc agcggaggac cattaatcat
    29041 gacggataat ccgaataaaa aaacattctg ggataaagtc catctcgatc ccacaatgct
    29101 gctgatctta ctggcattgc tggtttacag cgccctggtt atctggagcg ccagcggtca
    29161 ggatattggc atgatggagc gtaaaatcgg ccaaatcgcg atgggtctgg tcatcatggt
    29221 ggtgatggcg caaattcctc cacgcgttta tgaaggctgg gccccctatc tctatatcat
    29281 ctgtattatt ttgctggtgg cggtagatgc tttcggtgcc atctctaaag gtgctcaacg
    29341 ctggctggac ctcggtattg ttcgttttca gccgtcggaa attgccaaaa tagccgtacc
    29401 actgatggtt gcgcgcttta tcaaccgcga cgtttgcccg ccatcgttga agaacactgg
    29461 catcgcgctg gtgctgatat ttatgcccac gctgctggtg gctgcacagc ctgacctggg
    29521 aacatcaatc ctcgttgcgc tttccggtct gtttgtactg ttcctctctg gccttagctg
    29581 gcgtctgatt ggcgtcgcag tagtgctggt agcggcgttc attccgattc tgtggttctt
    29641 cctgatgcat gattaccagc gccagcgcgt aatgatgctc ctggacccgg aatcagaccc
    29701 actcggcgcg ggctatcaca ttattcagtc taaaattgct attggctccg gcggattacg
    29761 cggcaaaggc tggctgcacg gcactcagtc acagcttgaa tttctccccg aacgccatac
    29821 tgactttatc ttcgcggtac tggcggaaga gctgggatta gtgggcattc tgattctgct
    29881 cgctctctac attctgctga tcatgcgcgg gctgtggata gccgccagag cgcaaaccac
    29941 ctttggtcgc gtcatggctg gcggcttaat gctgatatta ttcgtttatg tcttcgtaaa
    30001 tattggtatg gtaagcggta ttctgccggt tgtaggggtt ccgctcccac tggtcagtta
    30061 tggaggatcg gcgctaattg tgctgatggc tgggttcggg attgtaatgt caatccacac
    30121 ccacaggaaa atgttgtcga aaagcgtgta agaggtgcgc aatgcgtaag cagtggctcg
    30181 ggatctgcat cgcggcagga atgctcgcgg catgtacaag cgatgatggt cagcaacaga
    30241 cggtaagtgt accgcagcct gcggtatgta acggccctat agttgaaatt agcggggcgg
    30301 acccgcgttt cgaaccactg aacgcgacgg caaatcagga ttaccagcgc gacggtaaaa
    30361 gctacaaaat cgtgcaggat ccgtctcgat ttagccaggc gggactggcg gcaatctatg
    30421 atgccgaacc cggcagtaac ctgacggcct ctggcgaagc attcgatccg acacagctga
    30481 cggcagccca tccaacgctt ccgatcccca gctacgccag aatcactaac ctggctaacg
    30541 ggcgaatgat cgtggtgcgc attaatgatc gcggccctta cggcaacgac cgcgttattt
    30601 cactttctcg cgcggcagct gaccgtctta acacgtcaaa caacaccaaa gttcgtatcg
    30661 atccgattat tgttgcccag gatggttcgc tttctggtcc tggtatggct tgtaccacag
    30721 tcgccaaaca gacttacgcc ctgcctgcac ctcccgattt aagcggtggc gcgggaacaa
    30781 gttcagtgtc tggcccgcag ggtgacattc ttccggtcag taattcgacg ctaaaaagcg
    30841 aagatccgac cggcgcgccg gtaaccagta gcggtttcct cggcgcacca acgaccttag
    30901 cgcctggtgt actggaaggc agcgaaccga cgcctgcgcc acagcccgtt gttacagctc
    30961 cgtcgacaac gcctgcaacc tcgcctgcaa tggtgacacc gcaagccgtc tcgcaaagcg
    31021 ccagcggcaa ctttatggtg caagtcgggg ccgtaagcga tcaggctcgt gcgcaacagt
    31081 accaacagca actgggacag aagttcggcg tccccggtcg cgtaactcaa aatggcgcgg
    31141 tctggcggat ccagcttggc ccattcgcca gcaaagccga agccagtacc ttgcagcaac
    31201 gtttgcaaac cgaagcccaa ttacagtcat ttattactac cgcgcagtag cgtaaagcag
    31261 gcatctgatg tgtcaatttc tgtaaatgac gttaacaaag tcacgcggaa agtcagatgc
    31321 ctgccggtag tgcatttgct atagtagggc acttttttaa ttccatcacg gatgtcgtag
    31381 ttcagaccat gaataccatt ttttccgctc gtatcatgaa gcgcctggcg ctcaccacgg
    31441 ctctttgcac agcctttatc tctgctgcac atgccgatga cctgaatatc aaaactatga
    31501 tcccgggtgt accgcagatc gatgcggagt cctacatcct gattgactat aactccggca
    31561 aagtgctcgc cgaacagaac gcagatgtcc gccgcgatcc tgccagcctg accaaaatga
    31621 tgaccagtta cgttatcggc caggcaatga aagccggtaa atttaaagaa actgatttag
    31681 tcactatcgg caacgacgca tgggccaccg gtaacccggt gtttaaaggt tcttcgctga
    31741 tgttcctcaa accgggcatg caggttccgg tttctcagct gatccgcggt attaacctgc
    31801 aatcgggtaa cgatgcttgt gtcgccatgg ccgattttgc cgctggtagc caggacgctt
    31861 ttgttggctt gatgaacagc tacgttaacg cactgggcct gaaaaatacc cacttccaga
    31921 cggtacatgg tctggatgct gatggtcagt acagctccgc gcgagatatg gcgctgatcg
    31981 gccaggcatt gatccgtgac gtaccgaatg aatactcgat ctataaagaa aaagaattta
    32041 cgtttaacgg tattcgccag ctgaaccgta acggcctgtt atgggataac agcctgaatg
    32101 tcgacggcat caaaaccgga cacactgaca aagcaggtta caaccttgtt gcttctgcga
    32161 ctgaaggcca gatgcgcttg atttctgcgg taatgggcgg acgtactttt aaaggccgtg
    32221 aagccgaaag taaaaaactg ctaacctggg gcttccgttt ctttgaaacc gttaacccac
    32281 tgaaagtagg taaagagttc gcctctgaac cggtttggtt tggtgattct gatcgcgctt
    32341 cgttaggggt tgataaagac gtgtacctga ccattccgcg tggtcgcatg aaagatctga
    32401 aagccagcta tgtgctgaac agcagtgaat tgcatgcgcc gctgcaaaag aatcaggtcg
    32461 tcggaactat caacttccag cttgatggca aaacgatcga gcaacgcccg ctggttgtgt
    32521 tgcaagaaat cccggaaggt aacttcttcg gcaaaatcat tgattacatt aaattaatgt
    32581 tccatcactg gtttggttaa aaattaaaca cttgaaagtg taatttccgt ccccatatac
    32641 taagcatcag taaaaaactc ccgccttctg gcgggagttg ctatttaatt acgttacgcc
    32701 ggagctgaca tgaaaaccaa acttaacgaa ctgcttgaat tccctactcc ttttacttac
    32761 aaagttatgg ggcaggcgtt acctgagctg gttgatcagg tggttgaagt ggtacagcgc
    32821 catgcgccag gtgactacac cccaacggta aaaccaagca gcaaaggcaa ctaccactcg
    32881 gtatctatca ctatcaacgc cactcatatc gagcaggttg aaacactgta tgaagaactg
    32941 ggcaaaatcg atattgtccg catggttctg taactcgctt ctccgttacc cggctcctgg
    33001 tcgggtaact cccctctcct cgctgtgata tacttttccc ccacttttac tcattctcca
    33061 cggagatgcc gttttgtatc aggataaaat tcttgtccgc cagctcggtc ttcagcctta
    33121 cgagccaatc tcccaggcta tgcatgaatt caccgatacc cgcgatgata gtacccttga
    33181 tgaaatctgg ctggtcgagc actatccggt attcacccaa ggtcaggcag gaaaagcgga
    33241 gcacatttta atgccgggtg atattccggt gatccagagc gatcgcggtg ggcaggtgac
    33301 ttatcacggg ccggggcaac aggtgatgta tgtgttgctt aacctgaaac gccgtaaact
    33361 cggtgtgcgt gaactggtga ccttgcttga gcaaacagtg gtgaataccc tggctgaact
    33421 gggtatagaa gcgcatcctc gggctgacgc gccaggtgtc tatgttgggg aaaagaaaat
    33481 ttgctcactg ggtttacgta ttcgacgcgg ttgttcattc cacggtctgg cattaaacgt
    33541 caatatggat ctttcaccat ttttacgtat taatccttgt gggtatgccg gaatggaaat
    33601 ggctaaaata tcacaatgga aacccgaagc gacgactaat aatattgctc cacgtttact
    33661 ggaaaatatt ttagcgctac taaacaatcc ggacttcgaa tatattaccg cttaattcca
    33721 tacatcaatg gcccaattta cactgggtca ttactcataa tatctgctaa tgctttacat
    33781 ctccttcgcg tttgtatatt ttctttatca cttgcagaaa tgcggtgcca cgccttgctc
    33841 cgtaactcac cccattgatt aacctattga aatagttgat tatggtgagc aaaagcgttc
    33901 cgttccaatt agacataaga ttattgtaat tttttaaata ttatttttcc atgaataaaa
    33961 ttggagtaag tgcgtggata gtaataatca aattgaaccc tgtttaagca gaaagtcgtc
    34021 agaaggtaaa ccacaaatat ttacaacctt acgaaatatt gatcttaacc ttctgactat
    34081 ttttgaagct gtatatgtac ataaagggat cgttaatgca gcgaaagtgc ttaatctgac
    34141 cccctcggca atcagtcagt ctattcagaa actgcgcgtt atattccctg acccattgtt
    34201 tattcgcaaa ggccagggtg tcactcctac cgcatttgcg atgcatctac atgagtatat
    34261 cagtcagggc cttgagtcca ttcttggcgc gctggatatc gaaggaagct atgataagca
    34321 acgaacgata actattgcga ccactccctc ggtcggagca ctggtccttc ctgtcatcta
    34381 tcgggcgatt aaaactcact atccgcagct tttactgcgc aacccgccca tcagcgacgc
    34441 ggaaaaccaa ctcagtcagt ttcaaaccga tctcatcatc gataacatgt tttgcaccaa
    34501 tcgtacggtg caacatcatg ttctgttcac cgacaatatg gtgttaattt gccgcgaggg
    34561 aaatccacta ctctctttag aagatgacag agagactatc gacaacgctg cgcatgtact
    34621 tctgttaccg gaagagcaaa atttcagcgg tctgcggcag agagttcaag aaatgtttcc
    34681 ggaccggcaa atcaatttca ccagctacaa cattttgaca atcgctgcac tggttgccaa
    34741 cagtgacatg ttagcgatta ttcccagccg tttttataac ctgtttagcc gctgctggcc
    34801 gctggaaaaa ctgccttttc cgtccttaaa tgaggagcaa atagatttct ctatccacta
    34861 caacaaattc agcctgcgtg atcccatcct gcacggagta atagatgtta tccgtaatgc
    34921 attttgaaaa agtattgtta cagccagatc acagcgcaga acgataaaat ggcacaatcc
    34981 aacaacaatt ttacattttc gcgaccgctt tggctgcttt caggtccgtt tcaatgatat
    35041 actgccagtc gttaattcaa aaatagttga taattacaac aatctattga attgaaacgc
    35101 tttccttcgt aattcgcaac tggaacacgc acgctatgag taaacccatt gtgatggaac
    35161 gcggtgttaa ataccgcgat gccgataaga tggcccttat cccggttaaa aacgtggcaa
    35221 cagagcgcga agccctgctg cgcaagccgg aatggatgaa aatcaagctt ccagcggact
    35281 ctacacgtat ccagggcatc aaagccgcaa tgcgcaaaaa tgacctgcat tctgtctgcg
    35341 aggaagcctc ctgccctaac ctggcggaat gcttcaacca cggcacagca acgtttatga
    35401 tcctcggcgc tatttgtacc cgccgttgtc cgttctgtga tgttgcccac ggtcgcccgg
    35461 tagctcctga tgccaatgaa ccagtgaaac tggcgcagac cattgccgat atggcgctgc
    35521 gttatgtggt tatcacctcc gttgaccgtg atgacctgcg cgatggcggt gcccagcact
    35581 ttgcggattg cattactgcc attcgggaaa aaagcccgca aatcaaaatt gaaactctgg
    35641 tgccggattt ccgcggtcgt atggatcgtg ctctggatat tctgactgca acgccaccag
    35701 atgtgttcaa ccataacctg gaaaacgtac cgcgtattta ccgtcaggta cggcctggtg
    35761 cagattacaa ctggtcgctg aagctgctgg aacgctttaa agaagcgcat ccggaaatcc
    35821 cgaccaagtc tggtctgatg gtgggactgg gtgaaaccaa tgaagaaatt attgaggtaa
    35881 tgcgcgacct gcgccgtcat ggtgtgacga tgttaacgct ggggcaatat ttgcagccaa
    35941 gccgccatca cctgccggtt caacgttacg ttagcccgga tgagttcgac gaaatgaaag
    36001 ccgaagcgct ggcgatgggc tttacccatg ctgcatgcgg tccgtttgtc cgctcttctt
    36061 accacgccga tttgcaggcg aaagggatgg aagttaagta atcctgtaat aattacttac
    36121 atctgtctga taaaaaaccc gctttttgaa gcgggttttt tgtatcgaac aagatattga
    36181 gggagcgtct tgctcgccac gtcactcttt atgagagagc ttttcagcct gaagatcaac
    36241 gtctgcgcct tttttcgccg cagcatcgtc atcattcatc gccttcttga accctttaat
    36301 ggccgctcca aggtctccgc ccagcgtacg taacttctta gtcccaaaca gcagaacgac
    36361 cagcgccgca actaccagca gtttggtaat actaatctca cccatagata ccttcttgac
    36421 atataaccgg caacagaacg cgccttaaaa accagagaat attaacggtc attcgacgcg
    36481 cgcacacaat agcaatctgt aacaaggtga atcaagcgcc gagtaaaaaa acatcataat
    36541 aattgcggcg gcgcaaagcg acggttgttt aagacgggca gttgcgcgcg cacctgacgc
    36601 acacgttcgg gcgtcacttc cgccataatg agtgcaggca tttctgacgc tgcc
//
LOCUS       DACAOP010000041        36353 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.041, whole genome shotgun sequence.
ACCESSION   DACAOP010000041 DACAOP010000000
VERSION     DACAOP010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36353
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.041"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..828
                     /gene="rhmD"
                     /locus_tag="IT892_002275"
     CDS             <1..828
                     /gene="rhmD"
                     /locus_tag="IT892_002275"
                     /EC_number="4.2.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnonate dehydratase"
                     /protein_id="HAP3135488.1"
                     /translation="GLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAVRDEIQFYATG
                     ARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGEDFWLMLDCWMSQD
                     VNYATKLAHACAPYNLKWIEECLPPQQYEGYRELKRNAPVGMMVTSGEHHGTLQSFRT
                     LSETGIDIMQPDVGWCGGLTTLVEIAAIAKSRGQLVVPHGSSVYSHHAVITFTNTPFN
                     EFLMTSPDCSTMRPQFDPILLNEPVPVNGRIHKSVLDKPGFGVELNRDCKLKRPYSH"
     gene            885..2174
                     /locus_tag="IT892_002276"
     CDS             885..2174
                     /locus_tag="IT892_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416749.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3135489.1"
                     /translation="MSTALLDAVVKKNRARLIPFMLALYVLAFLDRSNIGFAKQTYQI
                     DTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKLGARTWIGTTTLLWGFLSAAMAWAD
                     TEAKFLIVRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
                     GALLEMHGFMGHPGWFWMFVIEGLLAVGAGVFTFFWLDDTPEQARFLSKQEKKLLINQ
                     LASEEQQKVTSRLSDALRNGRVWQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFT
                     ASVVTAIPWVAALFGTWLIPRYSDKTGERRNVAALTLLAAGIGIGLSGLLSPVMAIVA
                     LCVAAIGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILRVKAETLFA
                     SDAAGLLTLAAVAVIGSLIIFTLRVNRTVAQTDVAHH"
     gene            2191..2994
                     /gene="yfaU"
                     /locus_tag="IT892_002277"
     CDS             2191..2994
                     /gene="yfaU"
                     /locus_tag="IT892_002277"
                     /EC_number="4.1.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxy-L-rhamnonate aldolase"
                     /protein_id="HAP3135490.1"
                     /translation="MNALLTNPFKERLRKGEVQIGLWLSSTTSYMAEIAATSGYDWLL
                     IDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEGSKSLIKQVLDIGAQTLLIPMVDTA
                     DQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDN
                     LDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAV
                     APDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKSGKNGPRIKGNY"
     gene            complement(3221..4180)
                     /locus_tag="IT892_002278"
     CDS             complement(3221..4180)
                     /locus_tag="IT892_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001561721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HAP3135491.1"
                     /translation="MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQT
                     LRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAA
                     MQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDIT
                     IVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQ
                     CGDTSRFTRFIEEIAERSPLQKERLMTIAERLRQEGHQIGWQEGKIEGWQEGKLEGLQ
                     KGKVEGMHEQAIKIALRMLEQGFEREIVLATTQLTDADIPNCY"
     gene            complement(4373..5563)
                     /gene="glpC"
                     /locus_tag="IT892_002279"
     CDS             complement(4373..5563)
                     /gene="glpC"
                     /locus_tag="IT892_002279"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit C"
                     /protein_id="HAP3135492.1"
                     /translation="MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLK
                     DGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMG
                     SVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYK
                     DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQ
                     AITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWR
                     KLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAG
                     TYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLA
                     QALA"
     gene            complement(5560..6819)
                     /gene="glpB"
                     /locus_tag="IT892_002280"
     CDS             complement(5560..6819)
                     /gene="glpB"
                     /locus_tag="IT892_002280"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase subunit GlpB"
                     /protein_id="HAP3135493.1"
                     /translation="MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGS
                     LDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYTLLGPQRVLDLACQAQALIAESGAQL
                     QGSVELAHQRVTPLGTLRSTWLSAPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLR
                     ELDLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMI
                     LMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPG
                     DEVKKVTCKNGVVNEIWTRNHTDIPLRPRFAVLASGSFFSGGLVAERDGIREPILGLD
                     VLQTSTRGEWYKGDFFAPQPWQQFGVTTDEALRPSQAEQTIENLFAIGSVLGGFDPIA
                     QGCGGGVCAVSALHAAQQIAQRAGGQQ"
     gene            complement(6809..8437)
                     /gene="glpA"
                     /locus_tag="IT892_002281"
     CDS             complement(6809..8437)
                     /gene="glpA"
                     /locus_tag="IT892_002281"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HAP3135494.1"
                     /translation="MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIAT
                     GATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLS
                     FQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLD
                     AKEHGAVILTAHEVTGLIREGATVCGVHVRNHLTGETQALHAPVVVNAAGIWGQHIAE
                     YADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYS
                     EIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIV
                     LLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADTPLPGSQEP
                     AEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVEN
                     LNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKG
                     VQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL"
     gene            8710..10068
                     /gene="glpT"
                     /locus_tag="IT892_002282"
     CDS             8710..10068
                     /gene="glpT"
                     /locus_tag="IT892_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HAP3135495.1"
                     /translation="MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLV
                     RKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLIL
                     AAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV
                     WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLP
                     PIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWS
                     PTYLKEVKHFALDKSSWAYFFYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTI
                     ATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
                     YLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHQELLQKRN
                     GG"
     gene            10073..11149
                     /gene="glpQ"
                     /locus_tag="IT892_002283"
     CDS             10073..11149
                     /gene="glpQ"
                     /locus_tag="IT892_002283"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP3135496.1"
                     /translation="MKLTLKNLSMAIMMSGMIMGSSAMAADSNEKIVIAHRGASGYLP
                     EHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRY
                     YAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNH
                     STGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYSGKDDKVYLQCFDADELKRI
                     KNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADG
                     IGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDAL
                     YNKAGVNGLFTDFPDKAVKFLNKE"
     gene            complement(11191..12069)
                     /locus_tag="IT892_002284"
     CDS             complement(11191..12069)
                     /locus_tag="IT892_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3135497.1"
                     /translation="MTLTQINSLLAVLDYGGFTEASKRLFMTQSAVSQAIAALEQELG
                     VSILLRDRRKAIQLTAAGHRIVHHLRAINREVNAVKEIAEQEKQNPQRTLRLGCFPSV
                     CACILPAVIRYFEIHHPNIKIIPFEENSTAIIDSLQNESIDAGFVHFPVSGMYSVPIY
                     QDKFTVVLPPNHALAKNSTITVEELMGEPLIISKGRYELSIMALFKEKNITPQIKYEF
                     NHPDTAISFIRQGLGIALLPELTLKTIADELCSVPLEPNFYRQISLLAKEKPVEGSPL
                     FLLQMCTEQLVEIGKI"
     gene            12221..13411
                     /locus_tag="IT892_002285"
     CDS             12221..13411
                     /locus_tag="IT892_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3135498.1"
                     /translation="MKEKLWTKDFWAITIISFIIFFVFYVLLTLLPIYISDRLHASPD
                     KAGLLVTLFLIAAIVIRPFAGQWVGKYSNKTILGLSSLAFLVVTALYPFCHSIESLLF
                     IRVLHGITFGVITTVKGTISARLIPASRRGEGISFFSLAMGLAMVVGPWIGLNMARWE
                     GFNLAFWLCTGVAAVGIILSLIMTVPPVISHADGSTPKMGFAAMFDRAALPFAMVTFF
                     MTFSYAGVSAFLALYARELNLMSAASNFLLCYAIFLMICRTFTGNVCDKKGPKYVVYP
                     CLVFFTVGLVVLGYTQGSIMMVVSGALIGIGYGSVTPVFQTQIISSVEPHKIGVANSL
                     FFNAMDAGLALGACVMGMMVAHTGYRMIYLLGALLVVVAGGVYALQMKGKSGVALVVA
                     KEIH"
     gene            13492..14142
                     /gene="inaA"
                     /locus_tag="IT892_002286"
     CDS             13492..14142
                     /gene="inaA"
                     /locus_tag="IT892_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide kinase InaA"
                     /protein_id="HAP3135499.1"
                     /translation="MAVSAKHDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKL
                     YVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALL
                     VTEDMAGFISIADWYARHAVTPYSDEVRQAMLKAVALAFKKMHSVNRQHGCCYVRHIY
                     VKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM"
     gene            complement(14196..14450)
                     /gene="yfaE"
                     /locus_tag="IT892_002287"
     CDS             complement(14196..14450)
                     /gene="yfaE"
                     /locus_tag="IT892_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like diferric-tyrosyl radical
                     cofactor maintenance protein YfaE"
                     /protein_id="HAP3135500.1"
                     /translation="MARITLRITGTQLLYQDEHPSLLAALESHNVAVEYQCREGYCGS
                     CRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEL"
     gene            complement(14450..15580)
                     /locus_tag="IT892_002288"
     CDS             complement(14450..15580)
                     /locus_tag="IT892_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-diphosphate reductase 1 subunit
                     beta"
                     /protein_id="HAP3135501.1"
                     /translation="MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQ
                     LSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISI
                     PELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDE
                     LIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFA
                     FAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDL
                     FVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIP
                     WINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL"
     gene            complement(15726..18011)
                     /gene="nrdA"
                     /locus_tag="IT892_002289"
     CDS             complement(15726..18011)
                     /gene="nrdA"
                     /locus_tag="IT892_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="HAP3135502.1"
                     /translation="MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELR
                     SHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPAL
                     YDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNR
                     VTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTP
                     TRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHT
                     GCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMD
                     YGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQR
                     VKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLN
                     DVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAM
                     GRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
                     WFNETTYAKGILPIDTYKKDLDAIANEPLHYDWEALRESIKTHGLRNSTLSALMPSET
                     SSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLV
                     GIMQKFIDQSISANTNYDPSHFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAED
                     AQDDLVPSIQDDGCESGACKI"
     gene            18707..22465
                     /gene="yfaL"
                     /locus_tag="IT892_002290"
     CDS             18707..22465
                     /gene="yfaL"
                     /locus_tag="IT892_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA-I family autotransporter adhesin YfaL/EhaC"
                     /protein_id="HAP3135503.1"
                     /translation="MRIIFLRKEYLSLLPSMIASLFSANGVAAVIDSCQGYDIKASCH
                     ASRQSLSGITQDWSIADGQWLVFSDMNNNASGGAVFLQQGAEFSLSPENETGMTLFAN
                     NTVSGEYNNGGAIFAKENSTLNLTDVIFSDNVAGGYGGAIYSSGTNDTGVVDLRVTNA
                     VFRNNIANDGKGGAIYTINNDVYLSEVIFDNNQAYTSTSYSDGDGGAIDVTDNNSNIT
                     HPSGFTIINNTAFTNNSAEGYGGAIYTNSVTAPYLIDISVDDSYSQNNGVLVDENNSA
                     AGYGDGPSTAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGVITKTGSG
                     DLVLNANNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDQYQN
                     QAELNVGSTQQTFVHALTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSY
                     VLAGAQSMALTGDIVVDDGAVLTLEGDAADLAALQDDPQSIVLNGGVLDLSDFATWQS
                     GTSYNDGLAVSGSSGTVIGSQDVVDLAGGNNMHIGGDGKDGVYVVVDAGDGLISLANN
                     NSYLGTTQIASGTLVVSDNSQLGDTHYNRQVIFTDNQQESVMEITANVDTRSTTTEHG
                     RDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSA
                     VRVEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSGTIDISDGTVLR
                     LTGQDTSVALNASLFNGDGTLVNTTDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNT
                     SGAVSLQNGVAGDTLRVNGDYTGGGTLLLDSELNGDDSASDQLVLNGNTAGNTTVVIN
                     PITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLR
                     SQEVTPPSPPDPDPTPDPDPTPDPDPTPDPAPDPTPAYQPVLNAKVGGYFNNLRAANQ
                     AFVMERHDHAGGNGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDG
                     EWMLGAVGGYSDNQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQ
                     YAWFNNDVSEHEDGVDHYHSSGIIASLEAGYQWLPGHGVVIEPQAQVIYQGVQQDDFT
                     AANHARVSQSQGDDIQTRLGLHSEWRTAVHVTPTLDLNYYYDPHSTKIEEDGSTISDE
                     AVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW"
     gene            complement(22526..23248)
                     /locus_tag="IT892_002291"
     CDS             complement(22526..23248)
                     /locus_tag="IT892_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-demethylubiquinone
                     3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol
                     methylase"
                     /protein_id="HAP3135504.1"
                     /translation="MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLR
                     LGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESG
                     IQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
                     NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNP
                     ITNTFKLGPGVDVNYMLHTQNK"
     gene            23395..26022
                     /gene="gyrA"
                     /locus_tag="IT892_002292"
     CDS             23395..26022
                     /gene="gyrA"
                     /locus_tag="IT892_002292"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /protein_id="HAP3135505.1"
                     /translation="MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPV
                     HRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDLAVYNTIVRMAQPFSLRYML
                     VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP
                     TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFP
                     TAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEK
                     IAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINM
                     VALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDP
                     IIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYL
                     TEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELEL
                     VREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKG
                     KSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLP
                     LEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVEGDEL
                     IGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRG
                     DGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMI
                     TDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAA
                     EGDDEIAPEVDVDDEPEEE"
     gene            26171..27859
                     /locus_tag="IT892_002293"
     CDS             26171..27859
                     /locus_tag="IT892_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416733.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2138 domain-containing protein"
                     /protein_id="HAP3135506.1"
                     /translation="MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSP
                     LVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIE
                     GSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPL
                     LFAATSDSQLSKTEISSIKLNSETIPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFK
                     DDQQDTEATAIASDLLSGKKRWQASFGLEERAAEKTPVRQRIVVSARLLGFGYQRLMP
                     SFAGVRFEMSNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAE
                     EMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGSAEQAQLPGKLFTQNI
                     GAHESKAPEGVLPVNQTQQGEAQIWRREVSSRYGQYPKTQAAQPDQLMSDYFFRVSLA
                     MQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGVAKLLRNETLT
                     SLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL"
     gene            27856..28479
                     /locus_tag="IT892_002294"
     CDS             27856..28479
                     /locus_tag="IT892_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1175 domain-containing protein"
                     /protein_id="HAP3135507.1"
                     /translation="MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQ
                     GPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGLSSQYLPPEMTLTPEQRQLAQNW
                     NQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYH
                     TGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR"
     gene            28623..33017
                     /locus_tag="IT892_002295"
     CDS             28623..33017
                     /locus_tag="IT892_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311138.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
                     /protein_id="HAP3135508.1"
                     /translation="MRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRI
                     VVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIIKP
                     SRYVQNNQFSPLKKYPLVKQFRYPLWQAKPFEPQQGVKLEGASSNFISPQPGNIYIPL
                     GQQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGKELLVWTAGKKQGEAKPGSEIL
                     WTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLY
                     IFTDRPLYRAGDRVDVKVIGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVNVTLDA
                     RNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEIGLALAKKEFKTG
                     EAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDAS
                     GHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGE
                     SVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGKSFTVNFAKPGNYNLTLRDK
                     DGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLER
                     DRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAG
                     IKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEI
                     APNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREE
                     VDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLY
                     MKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQ
                     NIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASN
                     IRLQSSETPQEIFRNNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQ
                     MIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQAIGVTQQPEYWQH
                     MLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDTR
                     DINDSLILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAH
                     TVVLLNSGGDATQTAAILSGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAK
                     HKLTGGGEDWRWVGQGVPDILSFGDELSPQNVQVRWREPAKMAQQSNIPVTVERQLYR
                     LIPGEEEMSFILQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERT
                     TWGISVNKPNAAKQQGQLLEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVL
                     PPARYVRSYAPAQQSVAAGSEWTGMQVK"
     gene            33018..34667
                     /locus_tag="IT892_002296"
     CDS             33018..34667
                     /locus_tag="IT892_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2300 domain-containing protein"
                     /protein_id="HAP3135509.1"
                     /translation="MNWRRIVWLLALVTLPTLAEETPLQLVLRGAQHDQLYQLSSSGV
                     TKVSALPDSLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRD
                     TALVRSCGLYCAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLA
                     TLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTD
                     GTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKST
                     TAVNPGVLNGRYRVTFTNGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDRE
                     AKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTWARTMTAWT
                     QDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRS
                     TCQLLPKAKAWLAKKMPQWRRILQAETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRN
                     FFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD"
     gene            34672..35448
                     /locus_tag="IT892_002297"
     CDS             34672..35448
                     /locus_tag="IT892_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaP family protein"
                     /protein_id="HAP3135510.1"
                     /translation="MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASF
                     SQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSF
                     ARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHV
                     VTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPIHGRYQVYINYYGGRSETE
                     LTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW"
     gene            complement(35522..>36353)
                     /locus_tag="IT892_002298"
     CDS             complement(35522..>36353)
                     /locus_tag="IT892_002298"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HAP3135511.1"
                     /translation="SLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITA
                     ENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFP
                     KANSTAEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKS
                     YASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSE
                     KVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERLN
                     "
BASE COUNT         8602 a         8941 c         9945 g         8865 t
ORIGIN      
        1 ggcctggtga tgaatacgat ttcctgtgtc gatctggctc tgtgggatct gttcggcaaa
       61 gtggtcgggc ttccggttta taaactttta ggcggcgcag ttcgtgatga gattcagttc
      121 tacgctacag gcgcgcgccc ggatctggca aaagagatgg gctttatcgg tggcaaaatg
      181 ccgacgcact gggggccaca tgatggcgat gcggggatcc gcaaagatgc cgctatggtc
      241 gcggatatgc gtgaaaaatg cggtgaggat ttctggttaa tgctcgactg ctggatgagt
      301 caggacgtga actatgccac caagctggcc cacgcttgcg cgccctataa cctgaaatgg
      361 atcgaagagt gcctgccgcc acagcagtat gaaggttatc gcgaactgaa acgcaacgcg
      421 ccagtcggaa tgatggtcac cagcggtgag catcacggca cactgcaatc tttccgtacg
      481 ctttcagaaa ccggtatcga cattatgcag ccggatgttg gctggtgcgg tggcttaacc
      541 acgctggtgg aaattgccgc aatcgccaaa tccagagggc aactggtggt gccgcacggt
      601 tcgtctgttt actctcacca tgcggtgatc accttcacca atacgccatt caacgaattc
      661 ctgatgacca gcccggattg ttcaacgatg cgtccgcaat ttgatccgat tctgcttaat
      721 gagccggttc cggtgaatgg tcgtattcat aaatcagtgc ttgataaacc tggtttcggc
      781 gtcgaactca atcgtgactg caaattgaaa cgcccctaca gccactaatc actccgggcg
      841 ttgctgtgac aacggtaatg cccacatatt ctaaggagct ttttatgagc accgctttgc
      901 ttgatgccgt ggtgaagaaa aaccgtgcgc gtttaattcc gtttatgttg gcgctgtatg
      961 tgctggcgtt tctcgaccgt tcgaatatcg gttttgccaa acaaacctac cagattgata
     1021 ccgggctgag taatgaagct tatgcgctgg gagcaggcat tttctttgtg gtatacgcgt
     1081 ttctgggtgt tccggcgaat cttttgatgc gcaaactggg ggcaagaacc tggattggca
     1141 cgacaacact gctgtgggga tttctttcgg cagccatggc atgggccgat actgaagcga
     1201 aatttctgat cgttcgcact ctgcttggtg ctgcggaggc cgggtttttc cctggtatga
     1261 tttatctcac ctcgcaatgg tttccgcagc gtaatcgcgc cagcatcatg gggctgttct
     1321 atatgggcgc accgctggcg ttaacactgg gatcaccgct ttccggcgcg ctgctggaga
     1381 tgcatggatt tatggggcat cccggctggt tctggatgtt tgtgattgaa ggattgctgg
     1441 cagtcggcgc tggggtattc acattctttt ggcttgatga cacaccggag caggcacgtt
     1501 ttctgagtaa acaagaaaaa aaattgctta tcaatcaact ggcaagtgaa gaacaacaga
     1561 aagtgacttc tcgactgagc gatgcgctgc gtaatgggcg agtctggcaa ctggcgatta
     1621 tctacctgac cattcaggtg gcggtttacg gattaatttt cttcctgccg acgcaagttg
     1681 ctgcattgtt ggggacaaaa gtgggcttta cggcgtcggt ggtcaccgcc attccgtggg
     1741 tcgcggcatt gtttgggacc tggcttattc cgcgctattc cgataaaacc ggcgaacggc
     1801 gtaatgtcgc ggcgctgaca ttactggcgg cgggcattgg tattggtctg tccgggctgc
     1861 tttctccagt aatggcgatc gtagcgctgt gtgttgcagc catcgggttt attgccgtgc
     1921 agccggtgtt ctggacgatg ccgacacaac tgctttccgg tacggcgctg gctgcgggga
     1981 ttggttttgt aaacctgttt ggtgcagtgg gcgggtttat tgccccgatc ctgcgcgtga
     2041 aagcagaaac gttatttgcc agcgatgcgg cgggattact gacgctggca gcggtggcgg
     2101 tcatcggttc gctgattatt ttcactctgc gtgtaaatcg cactgttgcg cagaccgacg
     2161 tggcacatca ttaataggtt aaggaacacg atgaacgcat tattaaccaa tccctttaaa
     2221 gaacgtttac gcaagggcga agtgcaaatt ggtctgtggt taagctcgac tacttcttat
     2281 atggcagaaa ttgccgccac ttccggttat gactggttac tgattgacgg ggagcacgcg
     2341 ccaaacacca ttcaggatct ttatcaccag ctacaggcgg tagcgcccta tgccagccaa
     2401 cccgtgatcc gtccggtgga aggcagtaag tcgctgatta aacaagtcct ggatattggc
     2461 gcgcaaactc tactgatccc gatggtcgat actgccgatc aggcacgtca ggtggtgtct
     2521 gccacgcgct atcctcccta cggtgagcgt ggtgtcgggg ccagtgtggc acgggctgcg
     2581 cgctggggac gcattgagaa ttacatggcg caagtcaacg attcgctttg tctgttggtg
     2641 caggtggaaa gtaaaacagc actggataac ctggacgaaa tcctcgacgt cgaagggatt
     2701 gacggcgtgt ttattggacc tgcggatctt tctgcctcgt tgggctaccc ggataacgcc
     2761 gggcacccgg aagtgcagcg aattattgaa accagtattc ggcggatccg tgctgcgggt
     2821 aaagcggctg gttttctggc tgtggctcct gatatggcgc agcaatgcct ggcgtgggga
     2881 gcgaactttg tcgctgttgg cgttgacacg atgctctaca gcgatgccct ggatcaacga
     2941 ctggcgatgt ttaaatcagg caaaaatggg ccacgcataa aaggtaatta ttgatatcaa
     3001 aggcccatgg ggatcggctg tgggcctgtg ttaattagtg gttattcgct gccagatcgg
     3061 cttcgcttag ctgggtggct gcgagcacca ggtcacgatc aatgccctgt accagcatgc
     3121 gcaaagcaat tttaatggct tgtttacgca taccttcctg ccagccaatt tggtgtcctt
     3181 cctgccgtag ccgttcagca atagtcatta atctctcctt ttaataacag ttcggaatat
     3241 cagcatcagt gagttgggtt gtcgccagca caatctcacg ttcaaagccc tgttccagca
     3301 tgcgcaaggc aattttaatg gcttgttcat gcataccttc tactttgcct ttctgcaaac
     3361 cctccaattt cccctcctgc caaccttcaa ttttaccttc ctgccagcca atttgatgtc
     3421 cttcctgccg tagccgttca gcaatagtca ttaatctctc cttttgtagt ggtgaacgtt
     3481 cggcaatctc ctcaataaaa cgggtgaaac gggaggtatc gccgcattgc agcagataat
     3541 taaacagcgt ttgtagctgg ctgtcattag tgaagcctct aaccaaaagc gtggtgatcc
     3601 tgtcgaccat accgattaaa tcgcggtcgc gaatatgctt ttgaatcagt tcaagcagag
     3661 ctatacgccg atgttgcata atctcatcgt caggtacgat ggtgatatcc accaacggaa
     3721 aagcttcggt gtacaactgc cgggcaagtt gcggatcgtc aaactcatcc agccagttga
     3781 gtgagtacgg gtagggcgag gtttcgccat gataaaacag caatggcacc accagcggaa
     3841 ctctgtcata gcctttatcc aggtgacgct gcatggcggc agtggcatag cgcattagcc
     3901 gaaaagccat attcttttct gcagagcttt gatgttcaat cacgcagtag atataaccgt
     3961 caccgtcgct ggtttccacg gaccacaaaa catccgagta gtaagcgcgt aaactttttt
     4021 caataaaact ggtgggttcc aggcgtaagg tttgcaggtt gcaaagcttg cgcagcggct
     4081 ctggtagatg tatttccaga aaatcccgtg cggtttcggg tgtgaacata aaggttttaa
     4141 acaccgcatc atgcggggag gaggttgttg attcggtcat ggttgtccgt cacctgatat
     4201 ttatgatgac gcgacattac ggttatccca ggcctttgac atctgccagt tttagccttt
     4261 gcgagacgtt ttcagaggaa ttttcactgc gttgcaacgc atacattggg cacggaatcg
     4321 tgtacgcaaa aatgcccggt aacaacatgc ttaccgggca tcagaaagga gtttaagcca
     4381 gcgcctgggc cagcagcgta atcggatgtt cgcagcgaag acttgtggac atctcaatct
     4441 gccatttgca ggtttcgcag tcggtaacca ccagatctgc gccgctttct tctatctgac
     4501 ggaacagtgg tgcgccgatg gcttgtgagg tggggtagtt ctcttttttg aaaccgtaag
     4561 tacctgcaat accgcagcac tgggaatcca gcaccgttaa ctcaagtccc gggattttac
     4621 gcaacagctc tagggtgtag agcgtccagc ccattttttc catatggcac ggagtgtgat
     4681 aaaccacttt cagcggcagc ggtttcagcg gtaacgtttt gccttcgtcc agcttgcgcc
     4741 acagccagcg ggtcgccagt tcgatgtgat cgcgcaagcc tttgttgtcg acattcagca
     4801 cttctgggta ttcgtcgcgc agggcaaatg tacaggttga ggaggtggca atcaccggaa
     4861 tgccttttac tcccactgct tcgcggatcg actctacatt tgtgattgcc tgtttacgtg
     4921 ctttatcggt aaagccgttg gcgatcagcg gtacgccgca gcatttttct ttgctgagca
     4981 gttgtacacc ggtacccatt gcgttgagca ctttaattaa atctttgcct aactgcggat
     5041 ggttgtagtt aacgaagcag ccgtgaaaga aagccacctg gtctttatac tgcgcttgct
     5101 gggctgccac gctgcgatac cagcgacgga acgtgccgaa ggagtatttc ggtagcgtgc
     5161 ggcgatgatc gatttttaac gccgcatcaa gcagctgccg cactggtttc agcgaggtag
     5221 cggtattgac gattggtgcg aacggcgtgg aaacgctacc catcaggtcg gtatgactca
     5281 acacaaaatt gcgcagcgac gggcgtgtgg tgtcatattt cgcgcgcgcg cgctggatga
     5341 tatcgccaat cttcacatcg gacgggcagg cgacttcaca acgtttgcag ttgatgcaat
     5401 atttcagtgc ctcgtcatac agtgcgccat ctttcaaacg cagacgctcg ccatccggcc
     5461 cggcttgttt tggccccgga tatcccggat tcacccggct caccgggcag gcggtggtgc
     5521 agacggtgca cttaatgcag ttttcgaagc tggtgtcgtt cattgttgac ctcctgcgcg
     5581 ttgggcaatc tgttgagcgg catgtaaagc actgacggca caaacaccgc cgccgcatcc
     5641 ctgggcgatg ggatcaaatc cgcccagcac cgaaccgatg gcaaacaggt tctcaatggt
     5701 ttgctctgcc tgcgacgggc gtagtgcctc atcagtggtt acaccgaact gctgccacgg
     5761 ttgcggtgca aaaaaatcgc ccttatacca ttcaccccgc gtggaggttt gtagcacatc
     5821 aaggccgaga atcggctcgc gaatgccgtc acgttctgcc accagtccgc cgctaaagaa
     5881 actgccgctc gcaagcaccg caaatcgtgg gcgcagcggg atatcggtgt gattgcgcgt
     5941 ccagatttca ttcactacgc catttttaca ggtcactttt ttcacttcat cgcctggcat
     6001 ccacacgcca ccctggcgca caaactggcg ctgtaactgg ttttgcagac gaatgcccag
     6061 cacggaaggc ggcagcgttg gcaaaagcat cagtgaacaa ggtagttttt cattcaacca
     6121 acgccacagt ttgtcatcgg ccaggccgaa gcaggcgggc atcaggatca tttcgcaggt
     6181 attggcgaca ggaataagcg catcaagtaa cagcggccag ttttcttcat tatcaaggaa
     6241 acgggcgata ttcaccgcgc gaaactcggt ggcgttgttg cgcagcacat ccagttccgg
     6301 cagttcaatt tctgcggttt caacggcaag gtcgagttcg cgcaacgaag ccgccgcaag
     6361 atgcgcctga aaatccatca gaccgctaat tcctactaca catattttct tcgcgggcag
     6421 cggccagacg gggacttctg gcgcacttag ccaggttgag cgcagagtgc cgagtggcgt
     6481 aacccgctgg tgagccagtt ctacgctgcc ctgcaattgt gcaccgcttt cagcgattaa
     6541 tgcctgcgcc tggcaagcga gatcgagtac gcgttgtggc ccgagaagag tgtaaggatg
     6601 ggcaggtgcc tgctgacgca aagattccag tccactgtga atgtctgtca ccggttgacc
     6661 atccggcaga tggctcagca aatccagcga accggatgag aaatgcagcg cgctttgacc
     6721 acgagtgaca atggcacagc gcaggccgtg tttttgcagt tgcaggccac agagtaatcc
     6781 ggcgaggccg ccgcccataa tgacagtatc aaagcgcatc tttctgctcc ttctccagac
     6841 cacacagtcc ctgataaacc cagcgggtaa attcgctttc gcgcagtgcg tctccccatg
     6901 ctatgggttg cacgcctttc cagcgttcgt taaggaaggt ggaaagttgc tcgatagatt
     6961 gcgcggacgt cgtgacgtta aaccgttgca gcagtccggc agcccggcag gcgcagagtt
     7021 cgccctggca ggtacccatc cctacacggg tacgacggcg taaatccagc aggctgttaa
     7081 cgtttaaatt ttctactgcg tactgcactt cacccgcagt taccgcttcg cactcacata
     7141 ccaggctgcg gtgcaggcgg ccttcgctca gccaggctgg tgtgcgatcg ccgtgccggt
     7201 aaactgcgga accgcgcagc ggagcgggca gggagatcac tttgcgcagc gtgacttctg
     7261 ccggttcctg tgagccaggc aacggcgtgt cggcagtggt acaggggcgc gtgttgccca
     7321 gcttgcgaca caccgcgtca gtagcccatt ccgccatcag gcggtaggtc atcagtttgc
     7381 caccggtgat ggtgataaac ccgtccagac catcgcgttc agcatgatcg agcagcacga
     7441 tgccacggct gacgttacgt ccgcttggat cgtcatcgct ggcaaccagc ggacgcacgc
     7501 cagagtaagc ccgcaaaata cgcgttttcg ccatcacggg ggccagtttt tccccttcac
     7561 gcagcagaat atcaacttct tctgccgtca ctcgattatc gtcaatctcg ctgtaatcaa
     7621 tacgtaaaga ggtggtgcca atcagcgaaa tggtatcgcc aggcaccaga atatcggcgt
     7681 cggaaggttt gcggcagcgg ttgatcacat gctgattaat gcggtgatcc atgatcagca
     7741 gcgatccttt cgccgggaac atgcgaatgc gcagatcggc atattccgca atatgttgcc
     7801 cccagatccc ggcggcatta accacgacag gcgcatgaag tgcctgggtt tcgccggtga
     7861 ggtggttacg tacatgaacg ccgcacaccg tcgcgccttc acgaatgagt cccgtgactt
     7921 catgagcagt aaggataacc gcaccgtgtt ctttggcatc aagcatattt gctgcggtca
     7981 gacgaaatgg atcaacggtg ccatccggaa ctttcaccgc gccaatcagt gccgggttaa
     8041 cggcaggttc gataatgcgc gcttgctgcg ggtctatagc ttctgcgctg atccctgctt
     8101 cttcgcaggc gcggataaaa gtggcctgga aggagaggtc atcttccggc agggtgataa
     8161 acaggccgtt ggtcggttca acgcagtgac gtgcaatgcg tttcaggatc tggttttcac
     8221 taatacattc gcgggccgat tccgcatcgg ttaccgcata gcgcgcaccg ctgtgcagca
     8281 ggccgtggtt acgcccggtg gcaccggttg cgatgtcgtg gcgctcaacc aaaatcacgc
     8341 gcagcccgcg cagggcacag tcgcgggcaa ttccggctcc cgttgcaccg ccgccaatga
     8401 taatcacgtc acttgattgc gagtcgcgag ttttcattgt tatccctctg aagttcgttt
     8461 tttaccattt agccatagta aaaacatgaa ttgtttgatt tcgcgcatat tcgctcataa
     8521 ttcgaaagtg aaacgtgatt tcatgcgtca ttatgaacat ttaacccatc gtatttaata
     8581 atgtgtgcgg taattcacat ttaatttatg aatgttttct taacatcgcg gcaactcaag
     8641 aaacggcagg ttctcccact gaatcaggct gttaatcata aataagacca cgggccacgg
     8701 aggctatcaa tgttgagtat ttttaaacca gcgccacaca aagcgcgctt acctgccgcg
     8761 gagatcgatc cgacttatcg tcgattgcgc tggcaaattt tcctggggat attctttggt
     8821 tatgctgctt actatttggt tcgtaagaac tttgccctcg ctatgcctta tctggtcgag
     8881 cagggcttct cacgcggtga tttaggtttt gccctttcgg ggatctcgat tgcttatgga
     8941 ttttcgaaat tcatcatggg ctcggtgtca gatcgctcga atccgcgcgt tttcctgccc
     9001 gcaggtttga ttctggcggc ggcagtgatg ttgtttatgg gctttgtgcc gtgggcgacg
     9061 tcgagcatcg cggtgatgtt tgtactgttg ttcctctgcg gttggttcca ggggatgggg
     9121 tggccgccgt gtggtcgtac tatggtgcac tggtggtcgc agaaagaacg tggcggcatt
     9181 gtgtcagtgt ggaactgtgc acacaacgtc ggtggtggta ttccgccgct gctgttcctg
     9241 ctggggatgg cctggttcaa tgactggcac gcggcgctct atatgcccgc tttctgcgcc
     9301 attctggtgg cactgttcgc ctttgcgatg atgcgcgata ccccgcaatc ttgtggcctg
     9361 ccgccgatcg aagagtacaa aaatgattat ccggacgact ataacgaaaa agcggaacag
     9421 gagctgacgg cgaagcaaat cttcatgcag tacgtgctgc cgaacaaact gctgtggtac
     9481 atcgctatcg ccaacgtgtt cgtttatctg ctgcgttacg gcatcctcga ctggtcaccg
     9541 acttatctga aagaggtgaa acacttcgcg ctggataaat cctcctgggc ctacttcttc
     9601 tatgagtatg cgggcattcc gggcaccctg ctgtgcggct ggatgtcgga taaagtcttc
     9661 cgtggcaacc gtggggccac cggcgtcttc tttatgacac tggtgaccat cgcgactatc
     9721 gtttactgga tgaacccggc aggtaaccca accgtagata tgatttgtat gattgttatc
     9781 ggcttcctga tctacggccc tgtgatgctg atcggtctgc atgcgctgga actggcaccg
     9841 aaaaaagcgg caggtacggc agcgggcttt accggactgt ttggttacct gggcggttcg
     9901 gtggcggcga gcgcgattgt tggctacacc gtggacttct tcggctggga tggcggcttt
     9961 atggtaatga ttggcggcag cattctcgcg gttatcttgt tgattgttgt gatgattggc
    10021 gaaaaacgtc gccatcagga attactgcaa aaacgcaacg gaggctaatg gcatgaaatt
    10081 gacgctaaaa aaccttagca tggcgatcat gatgagtgga atgatcatgg gaagcagtgc
    10141 aatggcggcg gatagcaacg aaaaaatagt catcgcccat cgcggtgcca gtggatattt
    10201 gccggagcat acgctgccag caaaagcgat ggcgtatgcg cagggagcgg attatctgga
    10261 acaggatttg gtgatgacga aggacgacca tctggttgtc ctgcatgacc attatctcga
    10321 tcgtgttact gatgttgccg atcgtttccc ggatcgggcg cgcaaagacg gtcgttacta
    10381 cgcgatagat ttcacgctcg atgaaattaa gtcgctgaaa tttaccgaag gtttcgatat
    10441 tgaaaacggt aagaaagtac agacttatcc ggggcgtttc ccgatgggta aatctgactt
    10501 ccgggtacac actttcgaag aagagattga atttgttcag gggttaaatc actctaccgg
    10561 gaaaaatatc ggtatctatc cagaaattaa agcgccgtgg ttccatcatc aggaagggaa
    10621 ggatattgcg gctaaaacgc tggaagtgct gaagaaatat ggttacagcg gtaaggacga
    10681 caaagtttat ttgcaatgtt ttgatgccga tgaactgaag cgtattaaga atgagctgga
    10741 acctaaaatg ggcatggacc tcaatctggt acagctgatt gcctataccg actggaacga
    10801 aactcagcag aaacagccgg acggaagctg ggttaattac aactacgact ggatgtttaa
    10861 gccgggggcc atgaaacagg tggcggaata tgctgatggt attggtccgg attatcatat
    10921 gttgattgag gagacatcgc agccaggtaa tatcaaactc actggcatgg tgcaagatgc
    10981 tcagcagaat aaactggtag tgcatcctta caccgtgcgg tcagataagc tgcctgaata
    11041 cactactgat gtgaatcagt tatatgatgc tctgtataac aaagcgggtg taaatgggct
    11101 gtttactgat ttccctgata aggcagtaaa attccttaat aaagagtaat gctattgcag
    11161 gatggcgttc atgcgccatc ctgtctcaca tcaaattttt ccaatctcca ctaattgttc
    11221 cgtgcacatt tgcagtaaaa acagtggact gccttctacc ggcttttctt tagccagcaa
    11281 cgaaatctgt cgatagaagt ttggttcgag aggaacggaa cacaattcat ctgcaatggt
    11341 tttcagcgtt aactctggta ataaggcgat gcctaatccc tgtcgaataa aactgatcgc
    11401 tgtatccggg tgattaaatt catattttat ctgtggggta atattctttt ctttaaatag
    11461 tgccataatg cttaattcat agcgtccttt actaataatt aatggttcac ccattaactc
    11521 ttccactgta atagtgctgt tttttgccag agcatggttg ggcggtaaca ctacggtgaa
    11581 tttatcctga taaatgggca cggagtacat tccgctcacc ggaaaatgaa caaaaccggc
    11641 atcaatggat tcattctgaa gggaatcaat aatcgctgtg ctattttcct caaaaggaat
    11701 aatttttata ttcggatgat gaatttcaaa gtagcgaatc acagccggta agatacaggc
    11761 gcagacgctg gggaaacaac caagtctcag cgttctttga gggttctgct tttcctgctc
    11821 ggctatctct tttactgcgt tcacttcccg attaatggcg cgcagatgat gcacaatgcg
    11881 atgacctgct gcggtcagtt gtatagcttt acggcgatcg cgtaacagta tactcacgcc
    11941 aagttcttgt tcgagggcag caattgcctg acttaccgcc gactgcgtca tgaacaatcg
    12001 cttgctggct tcagtaaagc caccgtaatc cagcacggcg agtaaagaat ttatttgagt
    12061 aagagtcatt agagtttgct aatcaataat attaaaacga ttaatttctc taatagcgtg
    12121 ccgccattta tacttctgtt ctgcaaagta catcacaatt tgacgcaacc gcagtaacgg
    12181 gagtgttgtc tgcgtgcgtc atcctgacag gcggtagggt atgaaagaga agttatggac
    12241 gaaggatttt tgggcaataa ccatcatcag ctttattatt ttcttcgtct tttatgtttt
    12301 actaacattg ttgccaattt atatctcaga ccgcttgcat gcctctcctg ataaagcagg
    12361 tttgttggtg actttatttt taattgccgc cattgttatt cgcccctttg ccgggcaatg
    12421 ggtaggtaaa tattcgaata aaactattct ggggctctct tctctggcct ttttggtggt
    12481 cactgcgctg tatccttttt gccactcaat tgaatcactg ctttttattc gggtgcttca
    12541 tggtattacc ttcggggtta tcactacggt aaaaggaacg atttccgcgc ggctgatccc
    12601 ggcctcccga cgtggggagg gcatcagttt tttctctctg gcaatggggc tggcaatggt
    12661 ggtcgggccg tggattggtc tgaatatggc gcgctgggaa ggctttaatc tggctttctg
    12721 gctatgcacc ggcgtggcag cggtggggat tattctgtcg ctgattatga cagtgccgcc
    12781 ggttatcagc catgctgatg gttcaacgcc gaaaatgggc ttcgccgcca tgttcgatcg
    12841 cgcggcgttg ccatttgcga tggtcacctt ttttatgacc ttttcgtatg ccggggtttc
    12901 tgcttttctg gcgctttatg cacgcgaact taacctgatg tcggcagcca gtaatttcct
    12961 gctttgctac gctatcttcc tgatgatttg ccgtaccttt accggcaatg tctgcgacaa
    13021 aaaaggaccg aaatatgtgg tttacccttg ccttgtgttc tttacggtag gactggtggt
    13081 tctcggctac acccagggaa gcataatgat ggttgtttct ggcgcattga ttggtatcgg
    13141 gtatggttcc gtgacgccag tttttcagac gcagattatc agttcagtgg aaccgcataa
    13201 aatcggtgtc gcaaactccc tcttcttcaa tgcgatggat gcaggcctgg cgctgggagc
    13261 ctgtgtgatg gggatgatgg ttgcacatac tggctaccga atgatttatc tgctgggtgc
    13321 actattagtg gtagtggctg gcggagtcta tgcgctgcaa atgaagggta aaagcggtgt
    13381 cgcgctagta gtggcaaaag aaattcatta atacgacacg tttcattaag atttttcgca
    13441 ggtaaccacc tatagtcatt gtcgtaaata aaaaatgaca ggcgataggg tatggcagtt
    13501 tcagcaaagc acgacgaatt taatcactgg tgggcaacag agggcgactg ggttgaagag
    13561 cctaactatc gccgtaatgg tatgagcggg gtgcaatgcg tcgagcgcaa cggcaaaaag
    13621 ctatatgtaa agcgcatgac gcatcatctg tttcattccg tacgttatcc gttcggccga
    13681 ccaacgattg tccgtgaggt tgcggtaatt aaagaactgg agcgggctgg tgtcatcgtg
    13741 ccgaagattg tttttggtga agcggtgaaa attgaggggg aatggcgcgc gttgctggtg
    13801 actgaagata tggcggggtt catcagcatt gctgactggt atgcccggca tgcagtaacg
    13861 ccctattctg acgaagtacg gcaagccatg ttgaaagcag tggcgctggc gtttaagaaa
    13921 atgcatagcg ttaatcgtca gcatggctgt tgctatgttc gccatatcta tgtgaaaaca
    13981 gaaggtaagg cagaagctgg atttcttgat ctggagaaaa gtcgtcgccg cttgcgtcgc
    14041 gataaagcga ttaatcatga cttccgccag ctggaaaaat atctggagcc gatccccaaa
    14101 gcggactggg agcaggtgaa agcgtattac tacgccatgt aatcgttgta ggccagataa
    14161 tacgcgtaag cgtcgtatct ggcgctagta cccgatcaca actcgatttc aatatcgcct
    14221 tttgcccggc aacaacaagg caaaatttcc cccggctgaa taaaggctaa cggttcggca
    14281 atccagtcca cctggcctgc aacaaggcgc gtgcgacagg aaccgcagta accttcgcgg
    14341 cactggtact caaccgccac attgtgggat tccagcgccg ccagaaggga agggtgttca
    14401 tcctggtaca gcagttgtgt gccagtgatg cgcagggtaa tgcgagccat cagagctgga
    14461 agttactcaa atcgtcggtg tccacttccg agtcaatctg cccgaccaga taagaactga
    14521 cttccacttc ctgcggagca acctgcacgt tatcagacac cagccaggta ttgatccacg
    14581 ggatcgggtt ggagcgagtc tggaacggca gatccaaacc gactgcctgc atgcggatat
    14641 tggtgatgta ttcaacgtac tggcagagaa tgtctttatt cagaccaatc atcgaaccgt
    14701 cacggaacag ataatccgcc cagtctttct cttgctgtgc cgcctggaca aacaggtcat
    14761 agcattcctg cttacattct tcggcaattt ccgccatctc cggatcatcc gcgccgctgc
    14821 gcagcagatt cagcatatgc tgagtaccgg tcaggtgcag ggcttcatcg cgggcaatca
    14881 ggcgaataat tttggcgtta ccttccatca gttcgcgttc tgcaaaggca aaggaacaag
    14941 caaagctgac gtagaagcgg atcgcttcca gcgcgttaac gctcatcagg cagagataca
    15001 gttttttctt cagctcgcgc aggctaacgg ttacggtttt accgttaacg gtgtgggtac
    15061 cttcgcccag cagatgccag tagctggtca tttcgatcag ctcatcgtaa taactggaga
    15121 tcccttccgc acgtttctgg atctgctcgt tggtgacgat atcatcaaac acaacggacg
    15181 gatcgttaac gatattacga atgatatggg tataagaacg agagtgaatg gtttctgaga
    15241 acgcccaggt ttcgacccag gtttccagtt cagggatcga gatcagcggc agcagtgcca
    15301 cgttcgggct gcgaccctga atggagtcca gcagcgtctg atatttcagg ttgctgataa
    15361 agatgtgttt ttcgtgttca ggcagtgcct ggtaatcgat acggtcacga gaaacgtcaa
    15421 cttcttccgg acgccagaag aaagagagct gcttttcgat cagcttttcg aagatgtcat
    15481 atttttgctg atcgtagcga gccacgttga ccggctgacc aaagaacatc ggttctttca
    15541 gctgatcatt tttcgtctgt gaaaaggtgg tatatgccat gaatgtgtcc tgttgggagt
    15601 ttaatgccgg ataaggcatt ttacgccgca tcctgtgcct gatgcgacgc tggcgcgtct
    15661 tatcaggcct acaaaccgag ccgtaggccg gataaggcgt tcacgccgca tccggcatct
    15721 caatatcaga tcttacatgc gccgctttcg cagccatcgt cctggattga cggtaccaga
    15781 tcgtcctgcg cgtcttcagc gccgtcacgg gtgttctgat aatacagcgt tttgaccccg
    15841 aatttgtagg cggtgagcag gtctttcagc agttgctgca tcggcacttt tcctgacggg
    15901 aagtgtgacg gatcgtagtt ggtgttagca gagatcgact gatcgataaa tttctgcatg
    15961 atacccacca gttgcagata gccatcgtta cccggcattt cccacagcag ttcataggcg
    16021 tcgtgcagat gctcgtagtc cggcaccacc tggcgcagaa taccgtcttt cgacgctttg
    16081 atgctgacgt aaccacgcgg cggttcaata ccgttagtgg cgttagagat ctgcgaagag
    16141 gtctcggacg gcatcagagc agaaagcgtg gagttacgta gaccgtgcgt tttgattgac
    16201 tcacgcagtg cttcccagtc gtaatgcagc ggctcattag cgatggcatc cagatctttc
    16261 ttataggtat cgatcggcag gatccctttc gcgtaagtgg tttcgttaaa ccacgggcac
    16321 gcgccttgct ctttcgccag ctcattagag gctttcagca ggtaatactg aatggcttcg
    16381 aaggttttat gcgtcaggtt gttggcgctg ccgtcggagt agcgtttacc gtgcttcgcc
    16441 aggtagtaag cgaagttgat cacaccaata cccagcgtac gacgacccat cgctccacgt
    16501 ttggcggccg ggatcgggta atcctgatag tccagcagcg cgtcgagtgc gcgtaccgcc
    16561 agaatcgcca gctcttccag ttcatccagg ctattaattg cgcccaggtt gaaagcagac
    16621 agcgtacaca gcgcgatttc accgttctcg tcgttgacat cattcagcgg tttggtcggc
    16681 agggcgattt ccaggcacag gttagactgg cgcactggcg cgatggccgg atcaaacggg
    16741 ctatgggtat tgcagtggtc aacgttctga atatagatac gaccggtaga cgcacgttcc
    16801 tgcatcatca gcgagaacag ctcaacggct ttcacacgct gcttgcggat gctgtcgtct
    16861 ttctcatatt tggtgtacag gcgttcaaac tcttcctgat cggcgaagaa cgcgtcgtac
    16921 aaccccggta cgtcggatgg gctgaacaga gtgatatctt cacctttcag cagacgggta
    16981 tacatcagtt tgttgatttg taccccgtag tccatatgac gcacgcggtt gccttccacc
    17041 ccacggttgt ttttcaacac cagcaggctt tccacttcca gatgccacat cgggtagaac
    17101 agcgtagccg caccgccacg cacaccgccc tgagagcagg atttcaccgc tgtctggaaa
    17161 tgcttataga acggaataca accggtatgg aacgcttcgc caccgcgaat cgggctaccc
    17221 agcgcacgaa tacgcccggc attgatgccg atcccggcac gctgggaaac gtatttaaca
    17281 atcgcgctgg aggtggcgtt aatggaatcc aggctgtcac cgcactcgat cagtacgcag
    17341 gagctgaact gacgagtcgg ggtacgcacg ccggacatga ttggcgtcgg cagcgaaatt
    17401 ttaaatgtgg aaaccgcgtc gtaaaaacgc ttcacgtatt gtaggcgcgt ttcacgcggg
    17461 tagttcgaga acaggcacgc ggcaaccaga atataaagga actgggcgct ttcgtagatt
    17521 tcgccggtca cacggttctg caccagatat ttgccttcca gctgcttaac ggcagcataa
    17581 gagaaggtca tatcacggtc gtgatcgata aacgtgtcca tctgcttgaa ctcttcttcc
    17641 gtgtagtctt ccagcagatg attatcgtat ttgcccatct cgaccatttt caccacgtgg
    17701 tcgtacagcg caggcggctc aaactggccg taggcttttt tacgcaggtg gaagattgcc
    17761 aggcgcgcgg cgagatactg ataatccggc gcatcacggg agatcaggtc tgcggcagcc
    17821 ttgataatgg tttcgtggat gtcagaggtc ttgataccgt cataaaactg aatgtgggag
    17881 cgcagttcga cctgggaaat cgaaacgtta tgcagtcctt ctgccgccca atccagaacg
    17941 cgatggattt tgtcgagatt gatgcgctct gtgctaccgt cgcgctttgt caccagcaga
    18001 ttctgattca tgtatgtcgt acctgttttt ggaattcttt ccgcaatagt ttcgtgcaga
    18061 ctacctgtag tacgggaagc tgcttagaac actatatata gggggtatgt ttgggattca
    18121 ctgcaagata gtgtgaaaat ggccctcttg caagtgcata actttgtgga taactcagga
    18181 aggaaaaagt ggctttcgcg caccttaggt cagacaaggt gtccgggaaa gtcaatggga
    18241 agagaaaaat ttgttaaaaa taactgttcg gcgatttctt gaacggcaga ataggttgga
    18301 taaattgata tagatggttt attaatcttt ttgctaatga ttgcaaaaat tgatctaagt
    18361 acgagtcatc acataatctg atgtatcagt tgtggtcaat atataagcga atgtaagcga
    18421 ttgttgatgt cgaaatggtt gttttctctt cggttgttgt taaatgcgaa gccattttgt
    18481 taatttacct tatattataa gaaaattatt cattacttta attcagttta aacataactg
    18541 atatccctta aggtgattaa cttgaattat gacgcactga tattattcat gaaataataa
    18601 caaaatagcc attgcaccgg gttgaacaat ttacaaaaga aaaataaccc atatcgtata
    18661 atgcgattaa atatgccgtc ttatagaaaa tgatggtcag attaatatgc ggattatttt
    18721 tctacgcaag gagtatttat ctttactccc gtcaatgatt gcatctcttt tctctgctaa
    18781 cggtgtcgcg gcggtcattg attcatgtca gggatatgat atcaaagcga gttgtcacgc
    18841 cagcaggcaa agcctttcag gcattacgca ggactggagc atcgccgatg ggcaatggct
    18901 ggttttttcg gatatgaaca ataacgccag cggtggggcc gtatttttgc aacaaggagc
    18961 ggagttttct ctatcgccag aaaatgaaac tggaatgact ctgtttgcca ataatactgt
    19021 ctcaggagaa tataataacg gcggggcaat atttgctaaa gaaaactcaa cgctgaatct
    19081 tactgatgtt attttttccg ataacgttgc aggtggctat ggtggcgcaa tctattcttc
    19141 tggtactaac gataccggtg tcgtcgattt acgtgtcact aacgccgtgt ttcgcaataa
    19201 catcgctaat gacggcaaag gtggtgcaat ttataccatc aacaatgacg tctatttaag
    19261 tgaagttatt tttgataaca accaggcata tacatcaaca agttacagtg atggcgatgg
    19321 aggggcaatc gatgtcaccg ataataatag caatatcacg catccgtcag gtttcacaat
    19381 aataaataac accgcattta caaataactc tgctgaggga tatggtgggg cgatttatac
    19441 caatagcgtg acggctccct atcttattga tatttcagtt gatgacagct acagccagaa
    19501 caacggcgtg ttagtggatg agaacaacag cgcagcaggt tatggggatg gtccttccac
    19561 tgcggcgggc ggctttatgt atctcggctt aagtgaagtt acctttgata ttgccgacgg
    19621 aaaaacgctg gttatcggca atacagagaa tgacggagct gttgactcta ttgctggtac
    19681 cggggtaatc accaaaacag gttccggcga tctggtactt aatgcaaata acaatgactt
    19741 tactggcgag atgcagatag aaaacggtga agttaccctg ggccgcagca actccctgat
    19801 gaatgtcggc gatacgcatt gccaggacga tccgcaagac tgctacggtc tgacgatagg
    19861 gagtattgat cagtatcaga atcaggctga gctaaacgtt ggctcgaccc aacaaacttt
    19921 tgtgcacgca ttgacgggct ttcagaatgg cactttaaat atcgatgctg gtggcaatgt
    19981 tactgttaat caaggcagtt ttgctggcac catcgaaggt gctggtcagc tcaccattgc
    20041 gcaaaacggc agctacgtgc tggcaggggc acagtcgatg gcgctaactg gcgatatagt
    20101 cgttgatgat ggcgcggtgc ttacgctgga aggcgacgcg gcagatcttg ccgctctcca
    20161 ggacgatccg cagtcgatcg tgttaaacgg cggtgtgctt gatctctctg atttcgccac
    20221 ctggcagagc ggcacatcat acaacgatgg ccttgcagtc agcggcagca gcggaacggt
    20281 tatcggcagt caggatgtgg tagatcttgc aggcggaaac aatatgcata tcggcggcga
    20341 cgggaaagat ggcgtctacg tggtggttga tgcgggcgac gggctgatta gcctggcaaa
    20401 caataatagt tacctgggca ccacgcaaat cgcttccggt acgctggtgg tgagcgacaa
    20461 ctcgcagctt ggagataccc attacaaccg ccaggttatc tttaccgata atcaacaaga
    20521 aagcgtgatg gagattactg ccaatgtcga tactcgctct acaacgactg agcatgggcg
    20581 tgatattgaa atgcgcgccg acggtgaagt ggcagttgat gcgggggtag acacgcagtg
    20641 gggcgcactg atggctgaca gcagcgggca gcatcaggat gagggtagca cattgacgaa
    20701 aacgggggcg ggtacgctgg aactgaccgc cagcggtacg acgcagtcgg cggtacgtgt
    20761 cgaagaaggc acgctgcaag gcgatgttgc ggatatcttc ccttatgctt cgtcgctgtg
    20821 ggtcggtgac ggggcaacgt tcgttactgg cgcggatcag gatattcagt caattgatgc
    20881 tacttccagc ggcactatcg acatcagcga tggtacggtt ttgcgcctga ccgggcagga
    20941 tacttccgtc gcccttaatg cctcactgtt taacggcgat gggacgctgg tgaataccac
    21001 cgatggcgtg acgttgacag gtgagcttaa taccaacctt gaaactgaca gcctgactta
    21061 tctttccgac gtaacagtta atggcaatct gaccaatacg tccggtgcgg tcagcctgca
    21121 aaatggcgtc gctggcgaca cgctgagggt aaacggtgat tatactggcg gtggtacgct
    21181 actgctcgat agcgaattaa acggcgatga ctcggcaagt gaccaactgg tgttgaacgg
    21241 taatactgct ggcaacacga ccgtggtaat taatcccatt acgggtattg gtgagccgac
    21301 atcgacaggc attaaagtgg ttgatttcgc agccgatcca acgcaatttc aaaacaatgc
    21361 gcagttcagt ctggcgggca gcggctacgt caatatggga gcgtatgact acacgctggt
    21421 ggaagataac aacgactggt atctgcgatc gcaagaagta acgccaccat cgccacctga
    21481 tccagacccg actcccgatc ctgatcccac gccggatcct gatccaacac ccgacccggc
    21541 cccggaccct acgcctgctt atcagccggt gttgaatgcc aaagttggtg gatattttaa
    21601 taacctgcgg gcggcaaatc aggcgtttgt gatggagcga cacgatcacg ctggtggcaa
    21661 tggtcagacg ctgaatttac gtgttatcgg cggagattat cattacacag cagcggggca
    21721 actggctcag catgaagaca cttctacggt gcagcttagc ggcgacttgt ttagcgggcg
    21781 ctggggcacg gatggcgagt ggatgcttgg ggcggttggt ggctacagtg ataaccaggg
    21841 cgacagccgc tcgaatatga ccggaactcg cgccgataac cagaaccacg gttatgccgt
    21901 tggtctgacc tcaagctggt ttcagcacgg taatcagaag cagggggcct ggctggatag
    21961 ctggctgcaa tacgcgtggt ttaacaatga tgtttccgaa catgaagatg gcgtggatca
    22021 ttaccactca tcggggatta tcgcctcgct ggaagccggg tatcagtggt taccggggca
    22081 tggagtggtg attgaaccac aggcgcaggt gatttatcag ggcgtgcagc aggatgattt
    22141 tacagccgct aaccatgcgc gcgtgtcaca atcacagggc gatgatattc agacgcggct
    22201 gggtttacac agcgaatggc gtaccgctgt tcatgtcaca ccaacattag atctgaatta
    22261 ttattacgat ccccattcga cgaaaattga agaagatggc agcactatca gtgacgaagc
    22321 ggtaaaacaa cggggtgaaa taaaagtggg agtcacgggc aatatcagtc agcgagtgtc
    22381 cctgcgtggt agcgtggcgt ggcagaaagg gagtgatgat tttgcccaga cggcagggtt
    22441 tttgtcgatg acggtgaaat ggtagctgct ttgcgcccgg cattgtagcc ggatgtggtg
    22501 cgagcacctt atccggctaa caattttatt tattctgcgt gtgcagcata tagttcacat
    22561 cgacgccggg gccgagttta aaagtattag tgatcgggtt gtaatgtaac ccggttatat
    22621 gtcgctcttt aaggcttgtc tgatctaccc agccaagcag ttctgccggt tttataaatt
    22681 tcttcacgtc gtgcgtgcct ttgggcacca tgcgcaaaat atattccgcg ccaaccaccg
    22741 ccatcagcca tgacttgccg ttgcggttaa gcgtcgagaa aaagacatcg ccgcccggtt
    22801 tcaccagttg cgcacaggct ctgaccactg actgcggatc gggcacgtgc tccagcatct
    22861 ccatgcaggt caccacatca tactgcccgg catgttttgc cgcgtgctct tccacggttt
    22921 cctgcacgta atccacctga atgccgcttt ccagcgcgtg cagctttgcc acctgcaatg
    22981 gctcaaagcc catatccaga ccggtcaccg tcgcaccttc gcgcgccata ctctcggcca
    23041 gaatgccgcc gccacaaccg acatcgagca cctttttgcc aaataaaccg ccagcacgct
    23101 cggcaatata gcccagacgc agcgggttaa tgcggtgcag cggtttgaac tcaccttcaa
    23161 gatcccacca gcgggaggcg acggcttcaa atttagcgat ctcttcgtgg tctacgttat
    23221 ggtttaccgg cgatttttcg gcattcattg gcacttctac tccgtaattg gcaagacaaa
    23281 cgagtatatc aggcattgga tgtgaataaa gcgtataggt ttacctcaaa ctgcgcggct
    23341 gtgttataat ttgcgacctt tgaatccggg atacagtaga gggatagcgg ttagatgagc
    23401 gaccttgcga gagaaattac accggtcaac attgaggaag agctgaagag ctcctatctg
    23461 gattatgcga tgtcggtcat tgttggccgt gcgctgccag atgtccgaga tggcctgaag
    23521 ccggtacacc gtcgcgtact ttacgccatg aacgtactag gcaatgactg gaacaaagcc
    23581 tataaaaaat ctgcccgtgt cgttggtgac gtaatcggta aataccatcc ccatggtgac
    23641 ttggcggttt ataacacgat cgtccgtatg gcgcagccat tctcgctgcg ttacatgctg
    23701 gtagacggtc agggtaactt cggttccatc gacggcgact ctgcggcggc aatgcgttat
    23761 acggaaatcc gtctggcgaa aattgcccat gaactgatgg ccgatctcga aaaagagacg
    23821 gtcgatttcg ttgataacta tgacggcacg gaaaaaattc ccgacgtcat gccaaccaaa
    23881 attcctaacc tgctggtgaa cggttcttcc ggtatcgccg taggtatggc aaccaacatc
    23941 ccgccgcaca acctgacgga agttatcaac ggttgtctgg cgtatatcga tgatgaagac
    24001 atcagcattg aagggctgat ggaacacatc ccggggccgg acttcccgac ggcggcaatc
    24061 attaatggtc gtcgcggtat tgaagaagct taccgtaccg gtcgcggcaa ggtatatatc
    24121 cgcgcccgtg ctgaagtgga agttgacgcc aaaaccggac gtgaaaccat tatcgtccat
    24181 gaaattccgt atcaggtgaa caaagcgcgc ctgatcgaga agattgcgga actggtaaaa
    24241 gaaaaacgcg tggaaggcat cagcgcgctg cgtgacgagt ctgacaaaga cggtatgcgc
    24301 atcgtgattg aagtgaaacg cgatgcggtt ggtgaagttg tgcttaacaa cctctactcc
    24361 cagacccagt tgcaggtttc tttcggtatc aacatggtgg cattgcacca tggtcagccg
    24421 aagatcatga acctgaaaga catcatcgcg gcgtttgttc gtcaccgccg tgaagtggtg
    24481 acccgtcgta ctattttcga actgcgtaaa gctcgcgatc gtgctcatat ccttgaagca
    24541 ttagccgtgg cgctggcgaa catcgacccg atcatcgaac tgatccgtca tgcgccgacg
    24601 cctgcagaag cgaaaactgc gctggtggct aatccgtggc agctgggcaa cgttgccgcg
    24661 atgctggaac gtgctggcga cgatgctgcg cgtccggaat ggctggagcc agagttcggc
    24721 gtgcgcgatg gtctgtacta tctgaccgaa cagcaagccc aggcaattct ggatctgcgt
    24781 ctgcagaaac tgaccggtct tgagcatgaa aaactgctcg acgaatacaa agagctgctg
    24841 gatcagatcg cagaactgct gcgtattctt ggcagtgccg atcgtctgat ggaagtgatc
    24901 cgcgaagagc tggaactggt tcgtgaacag ttcggtgaca aacgtcgcac tgaaatcacc
    24961 gccaacagcg cagacatcaa cctggaagat ctgatcactc aggaagatgt ggttgtgacg
    25021 ctctctcacc agggctacgt gaagtatcag ccgctttctg aatacgaagc gcagcgtcgt
    25081 ggcgggaaag gcaaatctgc cgcacgtatt aaagaagaag actttattga ccgactgctg
    25141 gtggcgaaca cccacgacca tattctgtgc ttctccagcc gtggtcgcgt ctattcgatg
    25201 aaagtctatc agttgccgga agccactcgt ggcgcgcgcg gtcgtccgat tgtcaacctg
    25261 ctgccgctgg agcaggacga acgtatcacc gcgatcctgc cggtgaccga gtttgaagaa
    25321 ggcgtgaaag tcttcatggc gaccgctaac ggtactgtga agaaaaccgt cctcaccgaa
    25381 ttcaaccgtc tgcgtaccgc cggtaaagtg gcgatcaaac tggttgaagg cgatgagctg
    25441 atcggcgttg acctgaccag cggcgaagac gaagtaatgc tgttctccgc cgaaggtaaa
    25501 gtggtgcgct ttaaagagtc ttctgtccgt gcgatgggct gcaacaccac cggtgttcgc
    25561 ggtattcgtt taggcgaagg cgataaagtc gtctctctga tcgtgcctcg tggcgatggc
    25621 gcaatcctca ccgcaacgca gaacggttat ggtaaacgta ccgcagtggc ggaatacccg
    25681 actaagtcgc gtgcgacgaa aggggttatc tccatcaagg ttaccgaacg taacggttta
    25741 gtggttggcg cggtgcaggt agatgactgc gaccagatca tgatgatcac cgatgccggt
    25801 acgctggtac gtactcgcgt ttcggaaatc agcatcgtgg gccgtaacac ccagggcgtg
    25861 atcctcatcc gtactgcgga agatgaaaac gtagtgggtc tgcaacgtgt tgctgaaccg
    25921 gttgacgagg aagatctgga taccatcgac ggcagtgccg cggaagggga cgatgaaatc
    25981 gctccggaag tggacgttga cgacgagcca gaagaagaat aattttactt cttcatgcca
    26041 aaagggagct atctcccttg tttgaattga aaagtccagg ctgcaaagtc tgggcttttg
    26101 tcgtattagg gcgcggtaaa gttttgctgt gctcgtaaaa aatggctggc tatacacaag
    26161 gaatgtggca atgagtggtg aaaaaaaggc gaaaggctgg cggttctatg gtcttgtagg
    26221 ttttggcgca atagcactgc tttccgctgg cgtctgggcg ttgcaatatg ctggcagtgg
    26281 gccagaaaaa acgttgtcgc cgctggtggt gcacaacaat ctgcaaatcg atctcaatga
    26341 gccggacctc tttctcgaca gcgactctct gagccagctt cccaaagatc tccttaccat
    26401 tccgtttctc cacgatgttc tgagtgaaga tttcgttttc tattatcaga atcatgccga
    26461 tcgtctgggc attgaaggca gcattcgccg cattgtctat gaacacgatc tcacgctgaa
    26521 agataagctc ttttcttcac tcttagatca gcccgcgcag gcggcgctat ggcacgataa
    26581 acaaggccat ctttcacatt acatggtgct gatccagcgc agtggtttaa gcaaactgct
    26641 ggagccattg ttgtttgccg ctaccagcga cagccagtta agcaaaacgg aaatcagtag
    26701 tattaagcta aatagtgaaa ccatcccggt ttatcagttg cgctataacg gcaataacgc
    26761 cctgatgttc gcgacttatc aggacaagat gttggtattt tccagcacgg atatgctgtt
    26821 taaagatgac cagcaggata ccgaagccac ggcgatcgca agtgatttgt tgagcggtaa
    26881 aaaacgctgg caagccagct ttggcctgga agagcgtgct gctgaaaaaa cgccagtacg
    26941 ccagcgcatc gtggtcagcg ccaggttgct ggggtttggc taccagcgat taatgccttc
    27001 ttttgctggc gtacgcttcg aaatgagcaa cgacggctgg catagctttg tggcgttaaa
    27061 tgatgaatcc gccagcgtag atgccagttt cgattttacg ccggtatgga acagtatgcc
    27121 tgccggggcc agcttctgtg tggcggtgcc gtattcgcat ggtattgccg aagagatgct
    27181 ttcgcacatc agccaggaaa acgacaagct gaacggggcg ttagatggtg cagccgggct
    27241 gtgctggtat gaagactcaa aattacaaac cccgctgttt gtcggtcaat ttgatggctc
    27301 agccgaacag gcacaactgc ctgggaaact gtttacgcaa aatattggtg cgcacgaaag
    27361 caaagcgcca gaaggtgttt tgccggtaaa ccagactcag cagggcgaag cgcaaatctg
    27421 gcgtcgcgaa gtgagttccc gatacggtca gtatccgaaa acacaggcgg cgcaacccga
    27481 tcaattaatg tcggattatt ttttccgcgt gtcgctggcg atgcaaaaca aaacgctgct
    27541 tttctccctc gatgacacgc tggttaataa cgccctgcaa acactgaata aaacccgtcc
    27601 ggcaatggtg gatgtaatac ccactgatgg catcgttccg ctctatatca atccacaagg
    27661 cgtggcgaaa ctgctgcgta acgaaacgtt gaccagtctg ccgaagaatc tcgaaccggt
    27721 tttttataac gccgcacaaa ctttattaat gccgaagctg gacgctttat ctcaacaacc
    27781 gcgttatgtc atgaagctgg cccagatgga acccggtgct gcctggcagt ggctacccat
    27841 aacctggcag ccgctatgag gcacgggctg ctggcgctga tttgctggct gtgttgtgtt
    27901 gttgcccata gcgaaatgct gaatgtcgaa cagtcggggc tgtttcgcgc ctggtttgta
    27961 cgcattgcac aagaacagct ccgccagggg ccaagtccac gctggtatca gcaggattgt
    28021 gcgggcctgg tgcgatttgc ggcgaacgag acgctgaaag ttcacgacag taaatggcta
    28081 aaaagtaacg gtttatctag ccagtatttg ccgccagaga tgacgctaac acctgaacag
    28141 cgtcaactgg cgcaaaactg gaatcagggg aacgggaaaa ccggccccta tgtgaccgcg
    28201 attaatttga ttcagtacaa cagccagttt attggccagg acataaacca ggcgctgcct
    28261 ggcgatatga tttttttcga tcagggcgat gcccagcact taatggtctg gatggggcgt
    28321 tacgtcatct accacaccgg aagcgccacg aaaactgaca acggaatgcg cgcagtcagt
    28381 ctgcaacaac ttatgacatg gaaggacacc cgatggatac ccaacgattc caatcccaat
    28441 ttcattggca tttatcgttt aaattttctg gcgcgatagc agcgtgcttg tccctgtctc
    28501 ttgtgggaac agggcttgct aatgctgatg attcgcttcc ttccagcaac tatgcgccgc
    28561 ctgccggggg aacattcttt ttgcttgctg acagcagttt tagcagcagt gaagaggcga
    28621 aagtgcgact ggaagcgccg gggcgtgatt atcggcgcta tcagatggaa gagtacggcg
    28681 gcgtggacgt tcgcctgtat cgtattcctg acccgatggc atttttgcgc cagcagaaaa
    28741 acctgcatcg cattgtggtg caaccgcaat atctgggcga cgggctgaac aatacgctaa
    28801 cctggctgtg ggataactgg tacggcaaat ctcgccgcgt gatgcagcgt actttctctt
    28861 ctcagtcacg gcagaatgtg actcaggcgt tacccgaatt acagctcggc aatgccatta
    28921 ttaaaccttc ccgttatgta cagaacaacc agttttcccc gctgaaaaaa tatcccctgg
    28981 tgaaacagtt ccgttatcca ctatggcagg ctaaaccgtt cgagccgcag caaggggtaa
    29041 aactggaagg cgcatccagc aatttcatct cgccgcagcc gggtaacatt tatattcctc
    29101 tcggccaaca agagccggga ctgtacctcg tcgaggcgat ggttggtggg tatcgggcga
    29161 cgacggtggt gtttgtttcc gataccgtgg cgcttagcaa agtgtcaggc aaagagcttc
    29221 tggtgtggac cgcgggtaaa aaacagggtg aagcgaagcc cggctcagag atcttgtgga
    29281 ctgacggtct tggcgtgatg acccgcggtg tgaccgatga cagcggtacc ttgcagttac
    29341 aacatatatc gccagaacgt tcatacattc tgggtaagga tgctgaaggc ggcgtttttg
    29401 tctccgagaa cttcttctac gaaagcgaaa tctacaacac ccgcttgtat atttttaccg
    29461 atcgcccgct atatcgcgca ggcgatcgtg tcgatgttaa agtgatcggc cgcgagttcc
    29521 acgatccgtt gcattcatcc cccatcgtca gcgccccggc gaagctttcg gtgctggacg
    29581 ccaacggcag tctgttgcaa accgtcaatg tcacgctgga tgcgcgcaat ggcgggcagg
    29641 gaagtttccg cctgccagaa aatgccgtag ccggaggtta tgagttacgt cttgcttacc
    29701 gcaatcaggt ctatagcagc agttttcgcg tggcaaacta catcaagcca catttcgaga
    29761 ttggtttagc tctcgccaaa aaagagttca aaactggcga agcggtcagc ggcaaactgc
    29821 aactgctcta cccggatggc gagccggtaa aaaatgcccg cgtgcagtta agtttgcgcg
    29881 ctcagcaatt atcaatggtc ggtaacgatt tgcgttatgc cggacgtttc cccgtgtcgc
    29941 tggaaggcag cgaaacggtg tccgacgcca gcggtcatgt ggcgttaaat ctccccgccg
    30001 ccgataaacc gagccgctat ttgttaaccg tctccgccag tgacggcgcg gcgtatcgcg
    30061 tcaccaccac caaagagatc ctcattgaac gcggtctggc gcattactca ttaagtactg
    30121 ccgcacaata cagtaatagc ggcgagtcgg ttgtgttccg ttatgccgcg ctggaatctt
    30181 caaaacaggt tcctgttacg tatgaatggt tgcgtctcga agaccgcacg agccatagcg
    30241 gagagctacc gtcaggcggc aaatccttta ccgtcaattt cgctaaacct ggcaactaca
    30301 atctgacatt acgcgataaa gacggcttaa ttctcgctgg gttaagtcat gccgtcagcg
    30361 gtaagggcag cacggcgcat actggtacgg tagatatcgt ggcggataaa acgctgtacc
    30421 agccaggcga aaccgcgaag atgctgatta cctttccgga gccaattgat gaagcattat
    30481 tgacgctgga acgcgatcgc gtggaacagc agtcgctgct ttcgcatccg gcaaactggc
    30541 taacgctaca acgtttaaac gatacccagt atgaagcccg ggttccagtg agcaattcct
    30601 ttgcgcctaa catcactttt tcggtgctgt atacccgtaa cggtcagtac agttttcaga
    30661 acgccgggat caaagttgcc gttccccagc tggatatccg ggtgaaaacg gacaaaaccc
    30721 attaccagcc tggtgaactg gtcaatgtcg aattaacctc gtcgctgaaa ggtaaacctg
    30781 tttctgcgca gctaacggta ggcgtggtcg atgaaatgat ctacgcgctg caaccagaaa
    30841 tcgcgccgaa tatcggcaaa tttttctatc cgctggggcg taacaatgtg cgtaccagct
    30901 ccagtctgtc gtttatcagc tacgaccagg cgctctccag cgagccggtt gcgcctggcg
    30961 caactaaccg cagcgagcgg cgagtaaaaa tgcttgaacg tccacggcgt gaagaggtgg
    31021 ataccgcggc atggatgccg tcactcacaa ccgataaaca aggcaaagcg tatttcacgt
    31081 tcctgatgcc tgattcgtta acccgctggc gtatcaccgc gcgtgggatg aacggcgacg
    31141 ggctggtcgg gcaggggcgt gcttatctgc gttcggaaaa aaatctctac atgaagtgga
    31201 gtatgccaac ggtgtatcgc gtgggcgaca aaccggcggc aggactgttt atcttcagtc
    31261 agcaggataa cgaaccggtg gcgctggtga ctaaatttgc aggcgctgag atgcgccaga
    31321 cgctgacgct gcacaaaggg gcgaattata tttcgctgac gcagaatatt cagcaatctg
    31381 gcttgttaag tgcagaactg caacaaaatg ggcaagtgca ggacagcatt agcacaaaac
    31441 tgtcttttgt ggataacagc tggcccgttg aacagcagaa aaatgtcatg ctcggtggtg
    31501 gcgataacgc gctgatgttg cccgagcagg cgagcaatat ccggctacaa agtagtgaaa
    31561 cgccgcagga gattttccgc aacaatcttg atgcgttagt cgatgaaccg tggggtggcg
    31621 taatcaacac cggtagccgt ctgatcccgc tcagtctcgc ctggcgttcg cttgccgatc
    31681 atcaaagtgc cgccgctaac gacattcgtc agatgattca ggataaccgt ctgcggctga
    31741 tgcaactggc ggggcccgga gcgcgcttta cctggtgggg tgaagatggc aatggtgacg
    31801 ccttccttac ggcatgggca tggtacgccg actggcaggc cagccaggcg atcggcgtaa
    31861 cgcaacaacc ggaatactgg cagcatatgc tcgacagcta cgcggagcag gcagataaca
    31921 tgccgttatt gcatcgggcg ctggtgctgg catgggcgca ggagatgaat ttgccgtgca
    31981 aaacgttgtt gaaagggttg gatgaagcta tcgcccggcg cggaactaaa actgaagatt
    32041 tctctgagga agacacccgc gatatcaatg atagcctgat cctcgataca ccggagtctc
    32101 cactggcaga tgcggtggca aacgtcttaa ccatgacgtt gctgaaaaaa gcgcagttga
    32161 agtccacggt gatgccacag gttcagcaat atgcgtggga taaagcggca aacagcaatc
    32221 agccgctggc gcacacggtt gtgctgctta atagcggtgg cgacgctacc cagacggccg
    32281 ctattttaag tggtttgacc gctgagcaat ccactattga gcgcgcgctg gccatgaact
    32341 ggctggcgaa atatatggcg acaatgcctc cagttgtttt gcctgcgcct gcgggcgcat
    32401 gggctaaaca taagttaact ggagggggcg aagactggcg ttgggttggt cagggcgtgc
    32461 cggacattct ctcttttggt gacgaattat cgccgcaaaa tgtgcaggtc cgctggcgtg
    32521 agccggcaaa aatggctcaa caaagtaaca ttccggtgac cgttgaacgc cagttgtatc
    32581 ggcttatccc tggtgaagaa gagatgagct ttattctgca accggtgacc agcaatgaga
    32641 ttgacagcga tgcgctgtat ctcgatgaaa tcacgcttac cagcgagcag gatgcagttc
    32701 tgcgctacgg tcaggtggaa gtaccgctgc caccgggagc cgacgttgag cgcacaacat
    32761 ggggcatttc ggtcaataaa cccaacgccg cgaaacagca ggggcaattg ctggaaaaag
    32821 cgcgaaatga aatgggcgaa ctggcctata tggtgccggt gaaagaactg acgggaacgg
    32881 tcactttccg ccatttgctg cgcttctcgc aaaaagggca attcgttctg cctcctgctc
    32941 gttatgtgcg ttcctatgca cctgcgcagc aaagtgttgc ggcagggagt gaatggaccg
    33001 ggatgcaggt gaaataagtg aactggcgca gaatcgtctg gctattggcg ttggttactc
    33061 tgccaacact tgcggaggag acgccgttac aactggtgct gcgcggtgcg cagcacgatc
    33121 aactgtatca gctgtcgtca tcaggcgtga ccaaagtctc agcattacct gactcgctca
    33181 ccacgccgtt agggagtttg tggaaactgt atgtttacgc ctggctggag gatacccatc
    33241 aaccggagca gccctaccag tgtcgcggaa actccccgga agaggtttat tgttgtcagg
    33301 ctggggagag cataacgcgc gataccgcgc tggtacgttc ctgtgggctc tattgtgcgc
    33361 cgcagcggtt gcatattggc gcagatgtgt gggggcaata ctggcaacag cgtcaggcac
    33421 ctgcgtggtt agcgtctctg actacgctga agccagaaac ctcggtaacg gttaaatcgc
    33481 tgcttgattc attagcgacg ttacccgcgc aaaacaaagc tcaggaagtc ttactggatg
    33541 tggtgctgga cgaggcgaaa atcggtgtcg catccatgct cggtagtcgg gtacgggtga
    33601 aaacctggag ctggtttgcc gatgataaac aggaaatccg tcagggtggt tttgctggct
    33661 ggttaaccga tggtacaccg ctgtgggtta ctggcagtgg caccagcaaa acggtactaa
    33721 cccgttatgc gacggtgctt aatcgggttt tgccagtgcc gacgcaggtt gccagtgggc
    33781 aatgtgtaga ggtggagctg tttgcccgct atccgctgaa gaaaatcaca gcggaaaaga
    33841 gtacgacggc agtaaatccc ggcgtactta atgggcgcta tcgtgtgacg tttactaatg
    33901 gtaaccacat tacgtttgtc agccacggtg agacgacctt actgagcgaa aagggcaaac
    33961 tgaaattgca gtcgcatctc gatcgtgaag agtacgttgc cagagttctg gatcgcgagg
    34021 cgaaaagtac gccccctgag gcagcgaaag ccatgaccgt ggcgattcgc acttttttac
    34081 agcaaaacgc caatcgggaa ggcgattgcc tgaccatccc cgacagcagc gccacgcagc
    34141 gtgtttctgc ttcgccagcg accacgtggg cgcgaacgat gaccgcctgg acgcaggatc
    34201 tcatctatgc aggcgatccg gttcattatc atggcagtcg cgctaccgaa gggacacttt
    34261 cctggcggca agccacggcc caggcggggc agggagagcg ttacgatcag atactcgcgt
    34321 ttgcttatcc cgacaacagt cttagccgct ggggagcgcc acgctcaacc tgccagttat
    34381 tacccaaagc gaaagcctgg ctggcgaaaa aaatgccgca gtggcggcgt atattacaag
    34441 ctgagacggg gtacaacgaa ccagacgtgt ttgcggtttg ccgtttagtc tcaggtttcc
    34501 cctataccga tcggcagcag aaacggctgt ttattcgtaa cttctttacg cttcaggatc
    34561 ggctggattt aacccatgag tatctgcacc tggcctttga tggttatccc accgggcttg
    34621 atgagaacta tatcgaaacg ctgacccgac aattattaat ggactaatgc tatgcgaaag
    34681 atttttcttc cgttgttact ggtggcgctt tcgcctgtcg ctcacagtga aggtgtgcag
    34741 gaagtcgaga ttgatgcacc gctctcaggc tggcatccgg cagagggcga agatgccagt
    34801 ttttcacaat cgatcaatta cccggcgtcg tccgtcaaca tggcagatga tcaaaatatc
    34861 tcagcgcaga tccgcggcaa aataaagaat tatgctgcgg cgggtaaagt tcagcagggc
    34921 cggctggtgg tcaacggtgc cagtatgccg cagagaattg aatccgatgg ttcatttgca
    34981 cgcccttata ttttcactga aggcagcaac agcgtgcagg tcatcagccc ggatgggcaa
    35041 agccgacaaa aaatgcagtt ttactcaacg ccgggtacag gaacgattcg tgcacgttta
    35101 cggctggttc tctcgtggga tacggacaat accgacctcg accttcacgt tgttacgccc
    35161 gatggcgaac acgcctggta cggtaacacc gtgctgaaaa acagtggtgc actggatatg
    35221 gatgtcacga cggggtacgg acccgagatt ttcgccatgc ccgcgccaat tcacgggcgc
    35281 tatcaggtgt atatcaacta ctatggtggg cgcagcgaaa cggaattaac caccgcccaa
    35341 ctgacgctga tcaccgatga aggatcggtc aatgagaaac aggaaacatt tattgtaccg
    35401 atgcgtaatg ctggcgagct gacgctggtg aaaagttttg actggtgatt aatggggtta
    35461 ccttcgccgt cgatgttcaa gaaaacaccc gataactttc gctatcgggt gtttttattg
    35521 attaattcaa ccgttcaatc accatcgcaa ttccctgacc gccgccaatg cacagtgttg
    35581 ccagccccag cgttttatcg cgtgcctgca tggcatgtaa tagtgtgacc agaatacgag
    35641 caccactggc accgatagga tgcccgagcg cgatggcccc gccgttgaca ttcactttct
    35701 cagaatcaaa gcccaggttt ttcccaacgg caaggaactg tgcagcaaat gcttcattag
    35761 cctcaatgag atcaatatcc gccagttgca gccccgccag ttgtaacgct ttttgcgtgg
    35821 caggtactgg ccccataccc atcaatgcgg ggggcacgcc accgctggca taacttttaa
    35881 tgcgagccag gggggtaagg cctgctgcca gcgccgcaga ttcttccata atcaccagag
    35941 cggcagcacc gtcgttaata ccagacgcgt tcccagcggt gactgttcct gctttatcga
    36001 aggccgggcg caatgcacct aacgcttcag ccgttgaatt cgctttcggg aattcgtctt
    36061 gactgaagac gaaggttttc tttcgagtga caacatttac cgggacgatt tcggctgtaa
    36121 aagcaccgga ctcaattgcg gctgccgctt tacgctgtga atgtagcgcc agttcatcct
    36181 gcatttcacg ggtaattccg tactctttag ccacgttttc ggcggtaatc cccatatgat
    36241 aaccatgggt ggcgcacatc aggccatcgc gcaggattac gtcataaacc tgtccgtctc
    36301 caagacgata accagagcgt gcttttgcat cgagtaagta gggggctaaa ctc
//
LOCUS       DACAOP010000042        35435 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.042, whole genome shotgun sequence.
ACCESSION   DACAOP010000042 DACAOP010000000
VERSION     DACAOP010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35435
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.042"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            17..2245
                     /gene="crfC"
                     /locus_tag="IT892_002299"
                     /pseudo
     CDS             17..2245
                     /gene="crfC"
                     /locus_tag="IT892_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418533.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="clamp-binding protein CrfC"
     gene            2242..3120
                     /locus_tag="IT892_002300"
     CDS             2242..3120
                     /locus_tag="IT892_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418534.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135512.1"
                     /translation="MTKTLLDGPGRVLESVYPRFLVDLAQGDDARLPQAHQQQFRERL
                     MQELLSRVQLQTWTNGGMLNAPLSLRLTLVEKLASMLDPGHLALTQIAQHLALLQKMD
                     HRQHSAFPELPQQIAALYEWFSARCRWKEKALTQRGLLVQAGDQSEQIFTRWRAGAYN
                     AWSLPGRCFIVLEELRWGAFGDACRLGSPQAVALLLGDLLEKATQHLAESINAAPTTR
                     HYYHQWFASSTVPTGGEHADFLSWLGKWTTADKQPVCWSVTQRWQTVALGMPRLCSAQ
                     RLAGAMLEEIFSVNLA"
     gene            3384..4886
                     /locus_tag="IT892_002301"
     CDS             3384..4886
                     /locus_tag="IT892_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline/glycine betaine transporter ProP"
                     /protein_id="HAP3135513.1"
                     /translation="MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVY
                     GFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAIT
                     IVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRK
                     RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIPFFIALPLGIIGLYLR
                     HALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRSLLTCIGLVIATNVTYY
                     MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVA
                     LFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAA
                     FNISVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETANRPLKGAT
                     PAASDIQEAKEILVEHYDNIEQKIDDIDHEIADLQAKRTRLVQQHPRIDE"
     gene            4998..5087
                     /gene="pmrR"
                     /locus_tag="IT892_002302"
     CDS             4998..5087
                     /gene="pmrR"
                     /locus_tag="IT892_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxT activity modulator PmrR"
                     /protein_id="HAP3135514.1"
                     /translation="MKNRVYESLTTVFSVLVVSSFLYIWFATY"
     gene            complement(5063..6163)
                     /gene="pmrB"
                     /locus_tag="IT892_002303"
     CDS             complement(5063..6163)
                     /gene="pmrB"
                     /locus_tag="IT892_002303"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PmrB"
                     /protein_id="HAP3135515.1"
                     /translation="MNLMHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQI
                     QLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQ
                     KELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
                     LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLE
                     DVILPSYDELSTMLDQRQQTLLLPESAADITVQGDATLLRMLLRNLVENAHRYSPQGS
                     NIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQL
                     HHGQFFLQNRQETSGTRAWVRLKKDQYVANQI"
     gene            complement(6164..6832)
                     /gene="basR"
                     /locus_tag="IT892_002304"
     CDS             complement(6164..6832)
                     /gene="basR"
                     /locus_tag="IT892_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BasR"
                     /protein_id="HAP3135516.1"
                     /translation="MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGH
                     YSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKP
                     FALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR
                     LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVA
                     NEEN"
     gene            complement(6829..8472)
                     /gene="eptA"
                     /locus_tag="IT892_002305"
     CDS             complement(6829..8472)
                     /gene="eptA"
                     /locus_tag="IT892_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase EptA"
                     /protein_id="HAP3135517.1"
                     /translation="MLKRLLKRPSLNLLAWLLLAAFYISIYLNIAFFKQVLQALPLDS
                     LHNVLVFLSMPVVAFSVINIVLTLSSFLWLNRPLACLFILVGAAAQYFIMTYGIVIDR
                     SMIANIIDTTPAESYALMTPQMLLTLGFSGVLAALIACWIKIKPATSRLRSVLFRGAN
                     ILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVR
                     IGEDAHRNPLMQNEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTA
                     SCGTATAVSVPCMFSDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGACD
                     RVPHQNVTALNLPDQCINGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHGPTYYNR
                     YPPQFRKFTPTCDTNEIQTCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSL
                     VYLSDHGESLGENGIYLHGLPYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQ
                     TQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSE"
     gene            complement(8576..9913)
                     /gene="adiC"
                     /locus_tag="IT892_002306"
     CDS             complement(8576..9913)
                     /gene="adiC"
                     /locus_tag="IT892_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/agmatine antiporter"
                     /protein_id="HAP3135518.1"
                     /translation="MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIY
                     GWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNI
                     AMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALI
                     PIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVK
                     NPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGA
                     IVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILM
                     TIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTT
                     IAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD"
     gene            complement(10050..10811)
                     /locus_tag="IT892_002307"
     CDS             complement(10050..10811)
                     /locus_tag="IT892_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP3135519.1"
                     /translation="MRICSDQPCIVLLTEKDVWIRVNGKEPISLKANHMALLNCENNI
                     IDVSSLNNTLVAHISHDIIKDYLRFLNKDLSQIPVWQRSATPILTLPCLTPDVFRVAA
                     QHSMMPAETESEKERTRALLFTVLSRFLDSKKFVSLMMYMLRNCVSDSVYQIIESDIH
                     KDWNLSMVASCLCLSPSLLKKKLKSENTSYSQIITTCRMRYAVNELMMDGKNISQVSQ
                     SCGYNSTSYFISVFKDFYGMTPLHYVSQHRERTVA"
     gene            complement(11136..13403)
                     /gene="adiA"
                     /locus_tag="IT892_002308"
     CDS             complement(11136..13403)
                     /gene="adiA"
                     /locus_tag="IT892_002308"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418541.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase"
                     /protein_id="HAP3135520.1"
                     /translation="MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDG
                     FAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMD
                     RDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
                     GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVF
                     GADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSR
                     NRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQ
                     DLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALS
                     QASYIHVREGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEV
                     IDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQTGKTYDFADAPTKLLTTVQD
                     CWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVTAWLGRH
                     GIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKRHYDANTPLAQVMPELVEQYPD
                     TYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPVAEVTPREAYNAIVDNNVELVSI
                     ENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSYLRSLQSWDHHFPGFEHETEG
                     TEIIDGIYHVMCVKA"
     gene            complement(13602..14510)
                     /gene="melR"
                     /locus_tag="IT892_002309"
     CDS             complement(13602..14510)
                     /gene="melR"
                     /locus_tag="IT892_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MelR"
                     /protein_id="HAP3135521.1"
                     /translation="MNTDTFMCSSDEKQTRSPLSLYSEYQRMEIEFRAPHIMPTSHWH
                     GQVEVNVPFDGDVEYLINNEKVNINQGHITLFWACTPHQLTDTGTCQSMAIFNLPMHL
                     FLSWPLDKDLINHVTHGMVIKSLATQQLSPFEVRRWQQELNSPNEQIRQLAIDEIGLM
                     LKRFSLSGWEPILVNKTSRTHKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVK
                     LNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYS
                     TFGKYVGMSPQQYRKLSQQRRQTFPG"
     gene            14793..16148
                     /gene="melA"
                     /locus_tag="IT892_002310"
     CDS             14793..16148
                     /gene="melA"
                     /locus_tag="IT892_002310"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP3135522.1"
                     /translation="MMSAPKITFIGAGSTIFVKNILGDVFHREALKTAHIALMDIDPT
                     RLEESHIVVRKLMDSAGASGKITCHTQQKEALEDADFVVVAFQIGGYEPCTVTDFEVC
                     KRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPDATMLNYVNPMAMNTWAM
                     YARYPHIKQVGLCHSVQGTAEELARDLNIDPATLRYRCAGINHMAFYLELERKTADGS
                     YVNLYPELLAAYEAGQAPKPNIHGNTRCQNIVRYEMFKKLGYFVTESSEHFAEYTPWF
                     IKPGREDLIERYKVPLDEYPKRCVEQLANWHKELEEYKKASRIDIKPSREYASTIMNA
                     IWTGEPSVIYGNVRNDGLIDNLPQGCCVEVACLVDANGIQPTKVGTLPSHLAALMQTN
                     INVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIDEIYALVDDLIAAHGDWLPGWLH
                     R"
     gene            16263..17672
                     /gene="melB"
                     /locus_tag="IT892_002311"
     CDS             16263..17672
                     /gene="melB"
                     /locus_tag="IT892_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709821.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="melibiose:sodium transporter MelB"
                     /protein_id="HAP3135523.1"
                     /translation="MTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLVGTLF
                     LVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLANSVILFLLFSAHLFEGTTQI
                     VFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPYPRFFASLAGFVTAGVTL
                     PFVNYVGGGDRGFGFQMFTLVLIAFFIVSTIITLRNVHEVFSSDNQPSAEGSHLTLKA
                     IVALIYKNDQLSCLLGMALAYNVASNIITGFAIYYFSYVIGDADLFPYYLSYAGAANL
                     VTLVFFPRLVKSLSRRILWAGASILPVLSCGVLLLMALMSYHNVVLIVIAGILLNVGT
                     ALFWVLQVIMVADIVDYGEYKLHVRCESIAYSVQTMVVKGGSAFAAFFIAVVLGMIGY
                     VPNVEQSTQALLGMQFIMIALPTLFFMVTLILYFRFYRLNGDTLRRIQIHLLDKYRKV
                     PPEPVHADIPVGAVSDVKA"
     gene            complement(17811..18440)
                     /locus_tag="IT892_002312"
     CDS             complement(17811..18440)
                     /locus_tag="IT892_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2238 domain-containing protein"
                     /protein_id="HAP3135524.1"
                     /translation="MTRTLKPLILNTSALTLTLILIYTGISAHDKLTWLMEVTPVIIV
                     VQLLLATARRYPLTPLLYTLIFLHAIILMVGGQYTYAKVPVGFEVQEWLGLSRNPYDK
                     LGHFFQGLVPALVAREILVRGMYVRGRKMVAFLVCCVALAISAMYELIEWWAALAMGQ
                     GADDFLGTQGDQWDTQSDMFCALLGALTTVIFLARFHCRQLRRFGLITG"
     gene            complement(18563..20209)
                     /locus_tag="IT892_002313"
     CDS             complement(18563..20209)
                     /locus_tag="IT892_002313"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HAP3135525.1"
                     /translation="MSNKPFIYQAPFPMGKDNTEYYLLTSDYVSVADFDGETILKVEP
                     EALTLLAQQAFHDASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEETLSKGVYNTYIEDNLRYSQNAALDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAHYYDELPTEGNEHGQAFRDVQLEQEL
                     LEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIW
                     IEKLEHNPGQYIPQELRQAGEGEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVG
                     RDIAHAKLKELIDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDL
                     LQSHGGSMIMLAKGNRSQQVTDACHKHGGFYLGSIGGPAAVLAQQSIKHLECVAYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIVNKQCANCTK"
     gene            complement(20287..21627)
                     /locus_tag="IT892_002314"
     CDS             complement(20287..21627)
                     /locus_tag="IT892_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter"
                     /protein_id="HAP3135526.1"
                     /translation="MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQP
                     GKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTI
                     LCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
                     NVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREY
                     VYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMF
                     MLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLG
                     EMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYIL
                     PTYPSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL"
     gene            complement(22198..22917)
                     /gene="dcuR"
                     /locus_tag="IT892_002315"
     CDS             complement(22198..22917)
                     /gene="dcuR"
                     /locus_tag="IT892_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator DcuR"
                     /protein_id="HAP3135527.1"
                     /translation="MINVLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIF
                     NSDTPIDLILLDIYMQKENGLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVD
                     YLIKPFQASRFEEALTGWRQKKMALEKHQYYDQAELDQLIHGSSSNEQDPRRLPKGLT
                     PQTLRTLCQWIDAHQDYEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTG
                     RPVYRYRIQAEHYSLLKQYCQ"
     gene            complement(22914..24545)
                     /gene="dcuS"
                     /locus_tag="IT892_002316"
     CDS             complement(22914..24545)
                     /gene="dcuS"
                     /locus_tag="IT892_002316"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     DcuS"
                     /protein_id="HAP3135528.1"
                     /translation="MRHSLPYRMLRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQI
                     SDMTRDGLANKALAVARTLADSPEIRQGLQKKPQESGIQAIAEAVRKRNDLLFIVVTD
                     MQSLRYSHPEAQRIGQPFKGDDILKALNGEENVAINRGFLAQALRVFTPIYDENHKQI
                     GVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEIS
                     TLFEQRQAMLQSIKEGVVAVDDRGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQV
                     VDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAISTFRDKTEVRKLMQRL
                     DGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKI
                     KSPVIAGFLISKINRATDLGHTLILNSESQLPDSGSEDQVATLITTLGNLIENALEAL
                     GPEPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSERGVGLALVK
                     QQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR"
     gene            24726..24956
                     /gene="yjdI"
                     /locus_tag="IT892_002317"
     CDS             24726..24956
                     /gene="yjdI"
                     /locus_tag="IT892_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S mono-cluster protein YjdI"
                     /protein_id="HAP3135529.1"
                     /translation="MDQALLDGGYRCYTGEKIDVYFNTAICQHSGNCVRGNGKLFNLK
                     RKPWIMPDEVDVATVVKVIDTCPSGALKYRHK"
     gene            24968..25240
                     /locus_tag="IT892_002318"
     CDS             24968..25240
                     /locus_tag="IT892_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP3135530.1"
                     /translation="MEIREGHNKFYINDKQGKQIAEIVFVPTGENLAIIEHTDVDESL
                     KGQGIGKQLVAKVVEKMRREKRKIIPLCPFAKHEFDKTREYDDIRS"
     gene            25467..25763
                     /gene="ghoS"
                     /locus_tag="IT892_002319"
     CDS             25467..25763
                     /gene="ghoS"
                     /locus_tag="IT892_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HAP3135531.1"
                     /translation="MEGKNKFNTYVVSFDYPSSYSSVFLRLRSLMYDMNFSSIVADEY
                     GIPRQLNENSFAITTSLAASEIEDLIRLKCLDLPDIDFDLNIMTVDDYFRQFYK"
     gene            25791..25964
                     /gene="ghoT"
                     /locus_tag="IT892_002320"
     CDS             25791..25964
                     /gene="ghoT"
                     /locus_tag="IT892_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system toxin GhoT"
                     /protein_id="HAP3135532.1"
                     /translation="MALFSKILIFYVIGVNISFVIIWFISHEKTHIRLLSAFLVGITW
                     PMSLPVALLFSLF"
     gene            complement(26083..27600)
                     /gene="lysS"
                     /locus_tag="IT892_002321"
     CDS             complement(26083..27600)
                     /gene="lysS"
                     /locus_tag="IT892_002321"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAP3135533.1"
                     /translation="MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDH
                     TSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     SLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGA
                     SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG
                     DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK"
     gene            complement(27837..29294)
                     /gene="dtpC"
                     /locus_tag="IT892_002322"
     CDS             complement(27837..29294)
                     /gene="dtpC"
                     /locus_tag="IT892_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpC"
                     /protein_id="HAP3135534.1"
                     /translation="MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDN
                     HAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL
                     YLALAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
                     AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVM
                     LCLAPVFFTLLLENDWSGYLLAIVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTL
                     FWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVMLAGVVLAWLASPESR
                     GNSTLRVWLKFAFGLLLMACGFMLLAFDARHAAADGQASMGVMISGLALMGFAELFID
                     PVAIAQITRLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQ
                     MGEWTLACVAIIVVLAFATRFLFSTPTNMIQESND"
     gene            complement(29353..31500)
                     /gene="cadA"
                     /locus_tag="IT892_002323"
     CDS             complement(29353..31500)
                     /gene="cadA"
                     /locus_tag="IT892_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase CadA"
                     /protein_id="HAP3135535.1"
                     /translation="MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLK
                     LIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISF
                     FEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
                     SPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTN
                     GTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIP
                     QSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWV
                     PYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEA
                     YMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWF
                     FDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFG
                     IPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRV
                     KNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAF
                     QKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEI
                     GAHYPGFETDIHGAYRQADGRYTVKVLKEESKK"
     gene            complement(31580..32914)
                     /gene="cadB"
                     /locus_tag="IT892_002324"
     CDS             complement(31580..32914)
                     /gene="cadB"
                     /locus_tag="IT892_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadaverine/lysine antiporter"
                     /protein_id="HAP3135536.1"
                     /translation="MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWI
                     ISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGI
                     TAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVM
                     TAIVGWHWFDAATYAANWNTADTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKR
                     TVPLATMLGTGLAGIVYIAATQVLSGMYPSSVMAASGAPFAISASTILGNWAAPLVSA
                     FTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPKKGLLLAAVKMTALM
                     ILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFVSLICSVL
                     GCVFCFIALMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH"
     gene            complement(33279..34817)
                     /gene="cadC"
                     /locus_tag="IT892_002325"
     CDS             complement(33279..34817)
                     /gene="cadC"
                     /locus_tag="IT892_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator CadC"
                     /protein_id="HAP3135537.1"
                     /translation="MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHS
                     GEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMV
                     PVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFW
                     VWFFFLLSLGICVALVAFSSLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLS
                     YAIGVGDLVATSLNTFSTFMVHDKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSI
                     KLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQRMQETLQKILPHRG
                     ALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPL
                     DEKQLAALNTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSW
                     LNYVLLGKVYEMKGMNREAADAYLTAFNLRPGANTLYWIENGIFQTSVPYVVPYLDKF
                     LASE"
BASE COUNT         8966 a         8448 c         8878 g         9143 t
ORIGIN      
        1 taaggaagaa ttttctatgt acacacagac cctgtatgag ttaagtcagg aggctgaacg
       61 cctgttacag ctttctcgcc aacagttgca gttactggaa aaaatgcctc tctctgtacc
      121 cggagacgac gcgccacaac tggctttacc ctggagtcag cctaatatcg ccgaacgtca
      181 cgcgatgctg aataatgagt tgcgtaaaat ttcccgactg gaaatggtgc ttgcaattgt
      241 cggtaccatg aaagcaggga aatcaaccac cattaatgcc attgttggta cggaggttct
      301 gcctaatcgt aatcgcccaa tgactgcgct gccgacgctt attcgccata cgcccgggca
      361 aaaggaaccg gtactgcatt tttcacatgt cgcgccaatc gattgtttaa ttcaacaatt
      421 acaacagcgc ctgcgtgatt gcgatattaa gcatctgacc gatgtgctgg aaatagataa
      481 agatatgcgt gcgcttatgc agcggatcga aaatggcgtc gctttcgaaa aatattatct
      541 gggtgcccag cctatttttc attgtctgaa aagtttgaat gatttagtgc gactggcgaa
      601 ggcgctggac gtcgattttc ctttttctgc ttacgccgcc attgagcata ttcccgtgat
      661 tgaagtggag tttgtccatc tagcggggct ggagagttat cccggtcagt tgacgttact
      721 ggataccccc gggccaaatg aagccgggca accgcatctg caaaaaatgc ttaaccagca
      781 gctggcacgc gcctcggcgg tactggcggt gctggattat acgcaactga aatcgatctc
      841 cgatgaagag gtccgtgagg cgattttggc ggtggggcaa tcggtgccgc tgtacgtgct
      901 ggtcaataag ttcgatcaac aggatcgtaa cagtgacgac gccgaccagg tgcgggcact
      961 gatttccggg acgctgatga aaggctgtat tacgccacag cagatatttc cggtgtcgtc
     1021 gatgtggggc tacctggcga atcgggcgcg ctatgagtta gccaacaacg gtaagttacc
     1081 accgccagag caacaacgct gggtggaaga ttttgcccat gccgcgcttg gcaggcgctg
     1141 gcgtcatgcc gatctggcgg acctcgaaca tattcgtcat gctgccgatc agttgtggga
     1201 agattcgctg ttcgcccagc caattcaggc gttgcttcat gccgcttacg ctaacgcctc
     1261 gttgtatgct ctgcgatctg ccgcgcataa actgttgaat tacgcgcagc aggcgcggga
     1321 atacctggat tttcgtgcgc acgggttaaa cgtcgcttgt gaacaattgc ggcaaaatat
     1381 ccaccagatc gaagaaagtt tgcagctatt gcaactcaat caggcgcagg tgagcggcga
     1441 gattaaacat gaaatcgagc tggccctgac ctccgccaac cactttctgc gtcaacagca
     1501 agatgcgctg aaggtgcagt tagccgcctt gtttcaggat gattcggagc cgttaagcga
     1561 gattcgtacc cgctgtgaga cactgtgaca gacggcgcag aacaccatca gtcgcgactt
     1621 tacgctgcgt tttgccgagc ttgaatccac cctttgccgg gtgttaaccg atgttattcg
     1681 ccccattgag caacaagtca aaatggaatt gagcgagtca gggtttcgtc ctgggtttca
     1741 ttttcctgtt tttcacggcg tagttcccca cttcaacact cgccagctgt tcagtgaagt
     1801 catttcgcgc caggaagcaa cggacgagca gagcacgcgt ttaggcgttg tgcgtgagac
     1861 tttttcgcgc tggttgaatc agcccgactg gggacgggga aatgagaaat caccgacaga
     1921 aacggttgat tacagtgtgt tgcaacgagc attaagcgca gaagtcgatc tctattgcca
     1981 acaaatggct aaagttctgg cagagcaggt cgatgaatct gttacggcag gcatgaatac
     2041 ttttttcgct gagttcgctt catgtttgac ggaattacag acgcgtttac gcgaaagtct
     2101 ggctctgcgt caacaaaatg aatcggtggt caggctgatg cagcagcaat tgcagcagac
     2161 tgtgatgact cacggctgga tttacaccga cgcccagctg ttacgcgatg atattcaaac
     2221 acttttcacg gcagaacgat attgaccaag acgttacttg acggccccgg tcgcgtgctg
     2281 gagtcggttt atccccgctt tttagtggat ctggcgcagg gtgatgatgc ccgccttcca
     2341 caagcccatc agcagcagtt tcgtgaacga ctgatgcagg aacttctttc gcgtgtgcag
     2401 cttcagacat ggacgaacgg cggcatgtta aatgcgccgc ttagcctgcg tctgacattg
     2461 gtggaaaaac tggcgtcgat gctggatccc ggtcatctgg cactgacgca gatcgcgcag
     2521 catctggcgc tgctgcaaaa aatggatcac cgccagcact ctgctttccc ggagctcccc
     2581 cagcaaattg ccgccttgta tgagtggttt tcagcccgtt gtcgctggaa ggaaaaggcg
     2641 ttaacgcaac gaggcctact ggtgcaggca ggtgatcaga gcgagcaaat ttttacccgc
     2701 tggcgtgctg gggcgtataa cgcctggtcg ttgcctgggc gctgttttat cgttctggag
     2761 gagttgcgct ggggggcatt tggcgatgcc tgccgtctgg gaagcccgca agcggtggcg
     2821 ttgttgctgg gtgatttgct cgagaaagcg acacaacatc tggcagagag tatcaatgcg
     2881 gcaccgacca cgcgtcacta ttaccatcag tggtttgcct cttcgaccgt tccgacgggc
     2941 ggggagcatg ctgatttttt aagttggctg ggaaagtgga ccacggcaga taaacaaccc
     3001 gtttgctggt cagtgaccca acgctggcaa actgtcgcgc tggggatgcc acgactctgt
     3061 tcagcgcagc gtctggcggg ggcaatgctc gaggaaatct tctctgtaaa tttggcgtaa
     3121 ataatcagtt acatcaatga gtcctaaacg aaatccatgt gtgaagttga tcacaaattt
     3181 aaacactggt agggtaaaaa ggtcattaac tgcccaattc aggcgtcaac tggtttgatt
     3241 gtacattcct taaccggagg gtgtaagcaa acccgctacg cttgttacag agattgcatc
     3301 ctgcaattcc cgctcccctt ttgcggccgt cgcgctgatt tttctggcgt ttgcggaaat
     3361 gggccaactc tgcgaggaaa gctatgctga aaaggaaaaa agtaaaaccg attacccttc
     3421 gtgatgtcac cattattgat gacggtaaac tgcgtaaagc cattaccgca gcatcactgg
     3481 gtaatgcaat ggaatggttc gattttggtg tttatggttt tgttgcttac gcattaggta
     3541 aagttttttt cccgggggct gaccccagcg tgcagatggt tgctgcactt gccactttct
     3601 ccgttccctt tctgattcga ccgcttggcg gactcttctt tggtatgttg ggcgataaat
     3661 atggtcgcca gaagatcctc gctatcacta ttgtgattat gtcgatcagt acgttctgta
     3721 ttggcttaat accgtcctac gacacgattg gtatttgggc accgattctg ctgttgatct
     3781 gtaagatggc acaaggtttc tcggtcggcg gtgaatatac cggggcgtcg atatttgttg
     3841 cggaatactc ccctgaccgt aaacgtggct ttatgggcag ctggctggac ttcggttcta
     3901 ttgccgggtt tgtgctgggt gcgggcgtgg tggtgttaat ttcgaccatt gtcggcgaag
     3961 cgaacttcct cgattggggc tggcgtattc cgttctttat cgctctgccg ttagggatta
     4021 tcgggcttta cctgcgccat gcgctggaag agactccggc gttccagcag catgtcgata
     4081 aactggaaca gggcgaccgt gaaggtttgc aggatggccc gaaagtctcg tttaaagaga
     4141 ttgccactaa atactggcgc agcctgttga catgtattgg tctggtaatt gccaccaacg
     4201 tgacttacta catgttgctg acctatatgc cgagttattt gtcgcataac ctgcattact
     4261 ccgaagacca cggggtgctg attattatcg ccattatgat cggtatgctg tttgtccagc
     4321 cggtgatggg cttgctgagt gaccgttttg gccgtcgtcc gtttgtgcta cttggtagtg
     4381 ttgccctgtt tgtgttggcg atcccggcgt ttattctgat taacagtaac gtcatcggcc
     4441 tgatttttgc cgggttactg atgctggcgg tgatccttaa ctgctttacg ggcgttatgg
     4501 cttctacctt gccagcgatg ttcccgacgc atatccgtta cagcgcgctg gcggcggcat
     4561 ttaatatttc ggtgctggtt gccggtctga cgccaacgct ggcggcctgg ctggtcgaaa
     4621 gctcgcagaa tctgatgatg cctgcctatt acctgatggt agtggcggtg gttggtttaa
     4681 tcaccggcgt aaccatgaaa gagacggcaa atcgtccgtt gaaaggtgcg acaccggcgg
     4741 cgtcagatat acaggaagcg aaggaaattc tcgtcgagca ttacgataat atcgagcaga
     4801 aaatcgatga tattgaccac gagattgccg atttgcaggc gaaacgtacc cgcctggtgc
     4861 agcaacatcc gcgaattgat gaataagctg aaacggatgg cctgatgtga cgctgtctta
     4921 tcaggccaat tgaactctta aggttcactt aatctctgac gcgcatactc tcctccaggt
     4981 taacggagga gagtgcaatg aaaaaccgtg tttatgaaag tttaactacc gtgttcagcg
     5041 tgctggtggt cagcagcttt ctttatatct ggtttgccac gtactgatct ttcttcagcc
     5101 gtacccaggc ccgcgtgccg gaagtctctt gccggttttg caggaaaaac tgcccgtgat
     5161 gcaactgtgt aatgcggctg acaatactta accccagacc aatcccgcca taacggctgt
     5221 ccatacgtac aaacgcttta ctcaactccc cgcatttact ctcatcaata cctggtcctt
     5281 catcttcaac tgccatgacc gctccgtcat cttcttgcag cttaatcata atgttgctgc
     5341 cttgcgggct gtaacgatgg gcgttttcta ccaggtttcg caataacatc cgcagcaggg
     5401 ttgcatcacc ctgaacggtg atgtcggcgg cgctctctgg caatagcagg gtttgctgtc
     5461 gctggtcgag catggtactg agttcgtcat acgaggggag aatgacatct tccagcagtt
     5521 ttacatgttg ataattaccg gaagaaaatg actgtccggc acgcgccagt tgcagcagct
     5581 gggagacgct ctccatcatc tgatcaagcc gtgccactaa cggtgctaca tcaatgtgat
     5641 gcgttttcgc cagcagttcc agatgcaaac gcacccccgc cagtggcgtt cgcagttcgt
     5701 gcgcgacgtc agcggtaaac aacctttcgt tatccagcgt gctggtcagg cgactgacca
     5761 gatcgtttaa cgccgaaacc accgcttcga tttcgagggt ggcgctgtga atggcaatgg
     5821 gcgttaagtt gtcggcggtg cgcgcttcca gctctttttg cagctccgcc agcgggcggg
     5881 tgatgcggcg taccgcctga tagcagataa atagcgtcag gctgaccata aagacgccgg
     5941 ggacaatcag gctggcgacc gcctcgcgga tctcacgcat gatgtggcga tcgttgttgc
     6001 gattgtcgcg tagcgcctgc tcaaacagct gaatctgctc ggtactttca tgccatagcc
     6061 agaagacgct gatcagctca aacaccaaca aaatggcccc gatggtcaat atcagccgtt
     6121 ggcgcagcga tattggtcgg cgcagaaaat gcatcagatt caattagttt tcctcattcg
     6181 cgaccagcat atagccaaag ccgcgcacgg tgcggatacg ggctttgccc actttgtcgc
     6241 gcagattgtg gatatgcact tccagggtgt tggtcgaggg ttcattgtcc cagttataga
     6301 tgtcgttgta gagaatttcc cgatgcaccg gactgcctgc tttgagcatt aaccgtgaca
     6361 gcagagcata ttctttgggc gtcagaatca actcttcacc gcccatccat acctgacggc
     6421 gacccatgtt cagcgtcaga ttgccaacaa tcagctcact ttcgccctga ttattatggc
     6481 gtcgtagcag ggcgcggata cgggcatgta actcttccag cgcaaaaggc ttcaccagat
     6541 agtcgtcggc accgacatcc agcccggcga ttttgtcggt cagcgtatcg cgagcggtga
     6601 ggatcagtac cggcagggta tattttttct gccggatacg ggcgagaaaa tgcagtccat
     6661 cttcgtcggg taaccctaaa tccagtacca ccaggctgta atgacctgcc tcaaggcttt
     6721 gttccgccat ccgcgcggtt gtcacgccat cgcacgcgta gccttcggtt tgcgccgcca
     6781 gaatcagtcc ctgcaataac agcgtatcgt cttcaacaat cagaattttc attcactcac
     6841 tctcctgcaa gtttgcagaa tatcatccgc agcctggtaa tacttcgtct caacgccagt
     6901 taatcccaat agcgtggaga ataaattgtc ttgtgaatag tgttgcgttt gcgcctgttt
     6961 ttgcaggcag ttctggtcaa cctgataccg tttttgataa tcctccgaca gccacagcag
     7021 catcggcacc tgtttttggc tatccggggc gatggcataa ggcagaccgt gcagatagat
     7081 gccattttca cctaacgatt caccgtggtc agaaagataa accaggctgg tggtaaattt
     7141 atcctgatgt tctttcagca gattaatcgc tttatcaaca atatagtcga cgtaaaccag
     7201 cgtgttgtcg taagtgttca ccagttgctc tttggtacag gtctggatct cattggtgtc
     7261 gcaggttggg gtaaatttcc tgaactgagg cggatagcgg ttgtaatagg tcggaccgtg
     7321 gctgccgatg gtgtgtaaga caatcacgcc atcaccttgc aggttattga tgtactcttc
     7381 aagcccgtgg aacagcactt cgtcatagca ttcgccgttg atgcactgat caggtagatt
     7441 cagcgcggtg acgttctggt gaggcacgcg gtcgcaggca cctttacagc cgccatcgtt
     7501 gtcattccac agcacgttga tgcccgctcg ctgaatgata tccagcacgc cttcctggtg
     7561 ctgtgccagc tcttctttgt agtgctcacg cggcatatcc gagaacatgc acggtactga
     7621 aactgccgtt gccgtgccgc aagatgcggt attagggaaa tagaccacgt tatctttcgc
     7681 cagccgcggg ttagtttcac gcgggtagcc gttgagggag aagttctccg cccgcgaggt
     7741 ttcgccgaca atcaggatgg tcaaattttt acgtttttcg ttctgcatta acgggttgcg
     7801 gtgcgcgtct tcaccaattc gcaccagcgg cagatttgcc agtcgctgat gggagtacca
     7861 tgaccagctg gcaacaatgc tgttagaggg gcttaaggat ttcaccagct ctttgttatt
     7921 gcggaacaac gaggcgtagt ctttataaaa cagtgcggcg accagcaaaa tcagtagtac
     7981 agaaaccaga atattggctc cacggaaaag aacactgcgc agacgcgagg tggcaggttt
     8041 gatttttatc cagcaggcaa tcagcgcagc aagcacgccg ctgaatccca gcgttaataa
     8101 catttgcggt gtcatcagcg cataactttc tgccggagtg gtatcaataa tattggcaat
     8161 catcgagcgg tcgatgacga tgccgtaagt cattatgaaa tattgtgcag ccgcgccaac
     8221 cagaataaac aggcaggcca gtggtcgatt aagccataag aaagagctta gtgtcaggac
     8281 aatattaatc acgctgaaag cgacgaccgg catcgacaag aaaaccagta cgttatgcag
     8341 cgaatccagc ggcagcgcct gcaacacctg tttaaaaaag gcaatattca ggtagataga
     8401 gatataaaaa gcggccaaca atagccaggc gagtaaattc aaagagggtc tttttagtag
     8461 gcgcttcaac atcacggtgt ttccatcgaa caaagtgcgc atatgctcgc aaagcaaaat
     8521 taagccaacc ttaagttctt aaggttggct tttatgtttg ctggattaag gggaattaat
     8581 ctttgcttat tggtgcatct aagggatacg ggtttttatg tagccggttg taattcagcg
     8641 catacatggc ggtgatgacc atcagggtga caaatgacca cataacctct ttcgctccgg
     8701 accccaccac ggcccagatg cagtagagga aggcaatggt agtaactgcc agatatgccg
     8761 ggcgtgcttt accaaagtga ccgtgtccga gcagcagtaa cgccgcacag gtgtaaagat
     8821 atggcaccag tgtaaagatg accgagacgg aagaaaccag accgaactct ttggtcgcgt
     8881 ttggtgaaat gctgctgagc tggaagatgg tcatcaaaat accgacgata atcagccccg
     8941 ccactggcgt acccgcttta tttacacggg caaaaatcgg tgggaacagt ccgtcatcgg
     9001 cagcggcttt cgccgtttga cccgccagca acgtccagcc gcccagtgaa cctaagcaac
     9061 ccgcagctgc gcagaaggaa acaatggccc cggcggtgtc acccaacgcc atccgtgcgg
     9121 catcaccgaa tggcgaagca gaaacgcgca gtgcggcatt agggatcatc cccataatcg
     9181 cggtggtaga aagtacatag caaacggcgg caatcaatac cccaccaatg gtggcgatag
     9241 ggacattgcg tttcgggttt ttcaccacac ctgcggcaac ggaggcactt tccacaccga
     9301 tgaacgacca cagcgtaacg ttaagggtac tttgaattgc accgaaggtg cccaggccgc
     9361 tgacgttcca tgccgccata taggtttcac cacggaacca gaaccagcca aatacggcaa
     9421 tcccgacgat ggggatcagc gccagcacgg tggcaactgc ctgcacacgg gtgatcattt
     9481 tcggaccgac aatgttcagc aggacgaaga tccacagcac cacgacgcag gtgatggtta
     9541 ataccaatgg atctttcaga atcgggaaga agtaacttaa atatcctacg ccaatgacca
     9601 ccatggcgat attgccgatc cagcaggcca gccagtagag gacgttggtt tgataaccga
     9661 gaaacgggcc aaagcagcgg cgggcgtaag cgtaagaacc accaggactt gggtcgagga
     9721 acgacatttt ggcgtatacc atcgagagcc ccagtgcacc gataatcgtc accaaccatc
     9781 cataaatggc aatcccgcca gtagaggcca ggtttgcagg taacagaaaa acacctgacc
     9841 ccataatatt ccccgacacc atcagggtga cggggattaa gcccactttg tgagcatcag
     9901 catccgaaga cataattaaa ctcctgcgaa ggcgagcttc gtgacaataa attacgtcat
     9961 atcatacgcc tgcattcgat agttgaatta ttatcgaccg ggttatcgct gatgccgtta
    10021 ttaatatagc tcttcgttaa ggttaaaaat caggcgacag tgcgttctct gtgctgacta
    10081 acataatgca gcggcgtcat accgtagaag tctttaaaga cagaaataaa gtacgacgta
    10141 ctgttgtagc cgcaggactg tgatacctga gagatatttt taccgtccat cattaattca
    10201 tttacggcat aacgcatgcg gcaggtggtg attatttggc tataactggt gttttcgctt
    10261 ttcaactttt tctttaacag acttgggcta agacataaac aactggctac catactaaga
    10321 ttccagtctt tgtgaatatc gctttcaata atttgataaa cgctgtcact tacacaatta
    10381 cgtaacatat acatcattaa tgaaacgaat tttttactgt cgagaaaacg ggatagcacc
    10441 gtgaataata atgcgcgtgt tcgttccttt tctgactcag tttctgcggg catcatgctg
    10501 tgttgcgcgg caacgcgaaa gacgtctggc gtcaggcatg gcagggtgag tatgggcgta
    10561 gcgctacgtt gccatactgg tatttgcgag agatctttat tcagaaaccg gaggtaatct
    10621 ttgatgatgt cgtgactaat atgagcaacc aaagtgttgt taagagagga gacgtcgata
    10681 atattatttt cacaatttaa taacgccata tggttagctt taaggctaat aggttctttc
    10741 ccattcaccc ttatccagac atctttttca gtcaataaaa caatacaagg ttggtcgctg
    10801 caaatcctca tacatgtact cctgagtgcg aataaaagac cagttctcgc taaagcaaag
    10861 cgataccggg aaatggttat ataattgtat gatgaatata aacatgcata aaaataacga
    10921 gttttactaa tagtacaaat ttttatagta atttctcatg tacatatttt tttacaggat
    10981 aaataacagg caaaaaaaag cgcggggtgg ggccgcgcaa aaagtatgac atttttgttt
    11041 gcagcaattt ttatgaaaac gttgccatac tcaaaaggcc taaggccagg cggcgtaatg
    11101 ttatttaaac aattacgcct tcagcggaat agtggttacg ctttcacgca cataacgtgg
    11161 taaataccgt caataatttc agtcccttca gtttcgtgtt caaatccagg gaaatggtgg
    11221 tcccaggatt gcagcgagcg taaataactt acttgcggac tgtttttatc gccgaagttt
    11281 tcaccagaca gcagcatcgg gattcctggc ggatacggga taactgagtt tgccgcgatg
    11341 cgtcctggca gattttcaat ggataccagt tcgacattgt tgtcgacaat cgcgttgtac
    11401 gcttcacgcg gggtgacttc cgccaccggc aggccggaat aggcttcgtt caaccgtgcg
    11461 ccagggttgt tttctttcag ccaggcaaac atggtgtcac ccagatcgtg aatccccatg
    11521 ttcgcgtaag tgtcaggata ttgttcaaca agttccggca tcacctgcgc cagcggtgtg
    11581 ttggcgtcat agtggcgttt gaaggagcaa agggtgttaa ccagagttcc ccatttccca
    11641 cgggttacgc ccatagagaa caggaacata atttggaagt cagtggtgcg ggtaggtaca
    11701 atgccgtggc gaccaagcca ggcagtgacc agcgccgccg gaacaccggt ttcttccagt
    11761 tcaccatctt cacccattcc cggagcaagg atgctgactt taatcgggtc gagcatactc
    11821 cagttatccg gaatatcttt gaagccgtgc cagctttcgc ccggatgcat tacccagcag
    11881 tcctgaacgg tggtcagcag tttggttggt gcgtcagcaa agtcataggt tttgccggtt
    11941 tgtgggtcgg tgacgacttc tttgttccac ggtttgaaga accagctacc gtcagcggtg
    12001 aactctttat atagccgcgc catcgcctga cggaaatcaa ccgcttcgtc aatcacttcc
    12061 tgtgtcagtg acaggccgct gttgccgtcc atcatcgaca ccgccacgtc gttggatgcg
    12121 cagatggcat acagcgggga ggtggtggca tgcatcatgt aggcctggtt gaagcgggag
    12181 aagttaatcg ccccacgacc ttcacgtaca tgaatataag aagcctgtga cagcgcattc
    12241 agcagtttgt gggtggagtg ggtggcgaaa acggtaggac cgttgtgatc gccaggttcg
    12301 ccgcgcatgg catagtgatc ggcatagatc gggttgaaac gtgcatagcc gtaccaggct
    12361 tcgtcaaagt gcagacgatc ggaggttttt tccagcagat cctgcgcttc tttagcgtta
    12421 taacacacgc cgtcataggt gcagttggtc accacgcagt aagacggttt ttgcccggct
    12481 ttgtctttgg tcagcgggct ttcactgatt ttcttctgca aggtttcagg ttgcatttcc
    12541 tgcggataga ttggcccgat aatgccgtag cggttgcggc ttggcaccat atagaccggt
    12601 ttcgcgcctg tcagcatcaa accttgttcg atggatttat ggcagttacg gtcaacgacc
    12661 acgacatcgt tatcggtcat gcaagcctgc atgatggtgc ggttagagcc ggaagtaccg
    12721 acgactaccg accaggagcg atcggcacca aatacgcgtg cggcatattt ttcgctttcg
    12781 ccaaatgcgc cagtatggtc aagcaaagaa ccgagggaag ttcgttcgat gcccatgtcg
    12841 gtgcggaaca gattttcacc atagtagtca tggtagaaac gtccggcggg tgttttggta
    12901 aaaccaacgc cgccctggtg gcctggcgct gcccaggaat attcatggat gtcactatat
    12961 ttcatcagcg cgctgaacag tggcggcaac agctgctggc ggtagcgggt catcgcggca
    13021 acggcgcgtc cggcgataaa gtcggcggta tcttccagaa tccaggcgaa ttcatcgaca
    13081 agctccagca ggtcgcgatc cattgcggcg agggcttttt cccgatcgcc caacaggaag
    13141 accggcacgt tttgttggcg ctcatgaagc ttaccgatca attgtctgac gttttgatgt
    13201 tcgtccggat gttccatttg atagctgaac atcaggcagt caatggcttc gtttgaagag
    13261 agaatggcaa aaccatcatc aaaggaggtg gatttaatca cggtaacatt ttgctggctt
    13321 aaagcatctg ccagacgctc aacggcgtta ccgacccagg tgtcttgatg gagaaactcg
    13381 ctttcaacaa ttaatacttt catcattgct tacccggtta tgaaggaatc ttcgttgcgg
    13441 gcaagtatct tccggccttt tcgggctgta aagcgcgtga aaaacaaaca tttttgaaat
    13501 atttagtttt ataaacaata cgttatgtga ttattttaaa ttattttcac tgcttattat
    13561 cgacggctaa actatttttt tggctgatac tgatatcgtc tttagccggg aaacgtctgg
    13621 cggcgctgtt ggctaagttt gcggtattgt tgcggcgaca tgccgacata tttgccgaac
    13681 gtgctgtaaa aacgactact tgaacgaaag cctgccgtca gggcaatatc gagaatactt
    13741 ttatcggtat cgctcagtaa cgcgcgaacg tggttgatgc gcatcgcggt aatgtactgt
    13801 ttcatcgtca attgcatgac ccgctggaat atccccattg catagttggc gttaagtttg
    13861 acgtgctcag ccacatcgtt gatggtcagc gcctgatcat agttttcggc aataaagccc
    13921 agcatctggc taacataaaa ttgcgcatgg cgcgagacgc tgtttttgtg tgtgcgcgag
    13981 gttttattga ccagaatcgg ttcccagcca gagaggctaa atcgcttgag catcaggcca
    14041 atttcatcaa tggcgagctg gcgaatttgc tcgttcggac tgtttaattc ctgctgccag
    14101 cggcgcactt caaacgggct aagttgctgt gtggccagtg atttgatcac catgccgtga
    14161 gtgacgtggt taatcaggtc tttatccagc ggccaggaga gaaacagatg catcggcaga
    14221 ttaaaaatcg ccatgctctg acaggttccg gtatctgtta gttggtgcgg tgtacaggcc
    14281 cagaacagcg tgatatgacc ctgattgata ttcacttttt cattgttgat caggtattcc
    14341 acatcgccat cgaaaggcac attcacttcg acctgaccat gccagtggct ggtgggcatg
    14401 atatgcggtg cgcgaaactc aatctccatc cgctggtatt ccgaatacag cgacagcggg
    14461 ctgcgggtct gtttttcgtc gctgctgcac ataaacgtat ctgtattcat ggatggctct
    14521 ctttcctgga atatcagaat tatggcagga gtgagggagg atgactgcga gtgggagcac
    14581 ggttttcacc ctcttcccag aggggcgagg ggactctccg agtatcatga ggccgaaaac
    14641 tctgcttttc aggtaattta ttcccataaa ctcagattta ctgctgcttc acgcaggatc
    14701 tgagtttatg ggaatgctca acctggaagc cggaggtttt ctgcagattc gcctgccatg
    14761 atgaagttat tcaagcaagc caggagatct gcatgatgtc tgcacccaaa attacattta
    14821 tcggcgctgg ttcgacgatt ttcgttaaaa atattcttgg tgatgtgttc catcgcgagg
    14881 cgctgaaaac ggcgcatatt gccctgatgg acattgaccc cacccgcctg gaagagtcgc
    14941 atattgtggt gcgtaagctg atggattcag caggggccag cggcaaaatc acctgccaca
    15001 cccaacagaa agaagcctta gaggatgccg attttgtcgt ggtggcattt cagattggcg
    15061 gttatgaacc ttgcacggtg actgatttcg aggtctgtaa gcggcatggt ctggaacaaa
    15121 ccattgccga tacgttgggg ccgggcggta ttatgcgcgc gctacgtacc attccgcatc
    15181 tgtggcaaat ttgcgaggac atgacggaag tctgccccga tgccaccatg ctcaactatg
    15241 ttaacccaat ggcgatgaat acctgggcga tgtatgcccg ctatccgcat atcaaacagg
    15301 tcgggctgtg ccattcggtg cagggaacgg cggaagagtt ggcgcgtgac ctcaatatcg
    15361 acccagctac gctgcgttac cgttgcgcag gtatcaacca tatggcgttt tacctggagc
    15421 tggagcgcaa aaccgccgac ggcagttatg tgaatctcta cccggaactg ctggcggctt
    15481 atgaagcagg gcaggcaccg aagccgaata ttcatggcaa tactcgctgc cagaatattg
    15541 tgcgctacga aatgttcaaa aagctgggct atttcgtcac ggaatcgtca gaacattttg
    15601 ctgagtacac accgtggttt attaagccag gtcgtgagga tttgattgag cgttataaag
    15661 taccgctgga tgagtacccg aaacgctgcg tcgagcagct ggcgaactgg cataaagagc
    15721 tggaggagta taaaaaagcc tcccggattg atattaaacc gtcacgggaa tatgccagca
    15781 caatcatgaa cgctatctgg actggcgagc cgagtgtgat ttacggcaac gtccgtaacg
    15841 atggtttgat tgataacctg ccacaaggat gttgcgtgga agtagcctgt ctggttgatg
    15901 ctaatggcat tcagccgacc aaagtcggta cgctaccttc gcatctggcc gccctgatgc
    15961 aaaccaacat caacgtacag acgctgctga ccgaagctat tcttacggaa aatcgcgacc
    16021 gtgtttacca cgccgcgatg atggacccgc atactgccgc cgtgctgggc attgacgaaa
    16081 tatatgctct tgttgacgac ctgattgccg cccacggcga ctggctgcca ggctggttgc
    16141 accgttaaaa cgcgactaaa cgctactgcg ccgggggatt tattccggcg cacacctctg
    16201 acgataccaa taacagaagg cgggcgttgg taacagcgac ccgataccct atgagcattt
    16261 caatgactac aaaactcagt tatggatttg gagcgttcgg gaaggatttt gcgatcggca
    16321 ttgtgtatat gtacctcatg tattactaca ccgatgtcgt cgggctgtct gtgggtttgg
    16381 tcggtacttt gtttctggtg gcgaggatct gggatgctat taacgatccg attatgggat
    16441 ggattgtaaa tgctacgcga tcgcgatggg gtaagttcaa accctggatc ctgatcggta
    16501 cgttggcaaa ctctgtaatc ttatttctcc tctttagtgc gcatctgttt gaaggtacta
    16561 ctcagattgt ctttgtttgc gtgacctaca tcctctgggg catgacttac accattatgg
    16621 atattccctt ctggtcgctg gttccaacca tcacgctcga taaacgtgag cgcgaacaac
    16681 tggttcctta tccgcgtttt tttgccagtc tggcaggctt tgttacggca ggtgtgacgc
    16741 taccatttgt taattatgtc ggcggtggcg atcggggatt tggctttcag atgttcactc
    16801 tggtactgat cgcctttttt attgtttcaa ccatcatcac tctgcgcaat gtgcatgaag
    16861 tcttttcgtc agacaatcaa ccgtctgctg aaggaagcca tctgacactt aaagccatcg
    16921 ttgcgctaat ttataaaaac gatcagcttt catgcctctt gggtatggct cttgcttata
    16981 atgtagccag caacattatt accggctttg ctatctatta tttctcatat gttatcggtg
    17041 atgcggattt gttcccctat tatctgtcgt atgcgggagc tgctaacctg gtgacgttag
    17101 tattcttccc acgcttagtt aaatcattat cccgacgcat tttatgggcc ggagcatcta
    17161 ttcttccggt gttaagctgt ggtgttctcc tgttaatggc attaatgagc tatcacaacg
    17221 tcgtcctcat tgtgattgcg ggtattttgc tgaatgtggg aacggcgctt ttctgggtat
    17281 tacaggtcat catggtggca gatatcgttg attacggtga atataaactg cacgtacgct
    17341 gtgaaagtat cgcttactcc gtgcagacta tggtggtgaa gggcggttca gcctttgcgg
    17401 cttttttcat tgcggttgtg ttagggatga ttggctatgt accgaatgtt gaacagtcta
    17461 cgcaagccct attaggtatg cagtttatta tgattgctct accaactctg tttttcatgg
    17521 taacgctgat tctctacttc cgtttctatc gcctcaatgg tgacacgctg cgcaggatcc
    17581 agatccatct gctggataaa tatcgcaaag taccgcccga gcctgttcat gctgatattc
    17641 cggtcggtgc agtgagtgat gtgaaagcct gacgtggaca atagctaacg aaaatggcct
    17701 gatgcgatat gtttatcagg ccacgtctta atgtaatgct ttggatttgc aaattttgta
    17761 gaccggataa ggaattcacg ccgcatccgg catcaacaaa gcgcaagttg ttatccggtt
    17821 atcaagccaa agcgccgtag ctggcggcaa tgaaagcgag cgaggaatat caccgtcgtt
    17881 aatgcgccaa gcagcgcgca gaacatatcg gattgcgtgt cccactggtc gccctgggtg
    17941 ccgagaaaat catccgctcc ctgacccatt gccagcgctg cccaccactc gattaattca
    18001 tacatcgcgc ttatcgccag cgccacgcag cagaccagga acgccaccat tttacgtccg
    18061 cgcacgtaca tcccgcgaac gagaatttct cgtgccacca gtgcaggcac cagcccctgg
    18121 aaaaagtgcc ccagcttgtc atacggatta cgactcaacc ccagccattc ctgcacctca
    18181 aaaccaacgg ggactttcgc gtaggtgtat tgtccgccga ccatcaggat gatggcgtga
    18241 aggaaaatga gcgtatagag cagcggcgtt aacggataac gtctggcggt ggcaagcagt
    18301 agctgcacga caataatcac cggtgtcact tccatcagcc aggtgagttt gtcatgggcc
    18361 gaaatgccgg tataaatcag gattaacgtt agcgtcagtg cgctggtgtt aagaattaac
    18421 ggcttgagtg tgcgggtcat ggtgagttcg caaatcaggg aaaatactga ctattcacca
    18481 gcaagcgtga aattacaatc gcaaaagagg tggcccaggg ggatcacctg gcagcatgct
    18541 gccaggcgct gggccgaaga ggttacttag tgcagttcgc gcactgtttg ttgacgattt
    18601 gctggaagaa gtcgttacct ttgtcatcga ccaggataaa cgccgggaaa tcttctactt
    18661 cgattttcca gatagcttcc atacccagct ccggataagc gacgcactcc agatgcttga
    18721 tgctctgctg cgccagtacc gccgccggac cgccgatgct accgaggtag aagccgccgt
    18781 gtttatgaca cgcgtcggta acctgctgac tgcggttacc tttcgccagc atgatcatgc
    18841 tgccgccgtg ggattgcagc agatccacgt aggagtccat acggcctgcg gtggttgggc
    18901 caagtgaacc tgatggataa ccggcagggg ttttcgccgg acccgcgtag tagatcgggt
    18961 gatctttgat gtactgcgga agttctttac cggcgtcaat cagctctttc agcttggcgt
    19021 gtgcaatatc tcggcccacg ataatggtgc cggtgagcga caaacgagtg gataccgggt
    19081 attgcgaaag ctgggcgagg atctctttca tcgggcggtt aaggtcaact ttcaccgctt
    19141 cgccttcacc ggcctggcgc agttcttgtg gaatgtactg gcctgggttg tgttccagtt
    19201 tttcgatcca gataccttcg cggttgattt tcgctttaat gttacggtca gcggagcagg
    19261 agacgcccat gccgaccggg caggatgcgc cgtgacgtgg cagacggata acgcgaatgt
    19321 cgtgcgcgaa gtatttaccg ccaaactgcg cgccaagacc gagtttctgg gcctcttcca
    19381 gcagttcctg ttccagctgg acatcgcgga acgcctgacc atgttcgttc ccttccgtcg
    19441 gcagttcatc gtaatagtga gcgcttgcta acttgacggt tttcaggttg gtttccgcag
    19501 acgtaccgcc aatcacaaac gcgatatggt acggcgggca ggctgcagta ccgagggtac
    19561 gcattttctc gacgaggaag tttttcagtt tgccgggagt cagcagggct ttggtttcct
    19621 ggtagagata cgttttgttg gcagagccgc cgcctttcgc aacgcaaagg aatttgtact
    19681 catcgccatc taccgcgtac aggtcgattt gcgcaggcag gttagtgccg gtgttgacct
    19741 ctttgtacat gtccagcgcc gcattctgtg aatagcgcag gttatcttcg atataggtgt
    19801 tatagacgcc tttcgacagc gtttcttcat caccgccgcc ggtccacacg cgctggcctt
    19861 ttttaccgac gatgatcgcg gtgccggtat cctggcaggt cggcagcacg cctttggcgg
    19921 cgatttcgga gtttcttaag aattgcagcg ccacgtactt gtcgttttcg ctggcttctg
    19981 gatcgtgaag aatagccgca acctgtttct ggtgtgccgg gcggagcata aaagaagcgt
    20041 cgtgaaaggc ttgctgcgcc agcagggtca gggcttctgg ttccactttc aggatggttt
    20101 cgccgtcgaa gtcggcaacg ctaacgtaat cggaagtgag tagatagtat tcggtattgt
    20161 ctttccccat cgggaaaggt gcctggtaga taaagggttt gtttgacata gcttccagcc
    20221 tgtaactctg tatttgttat tcgaaaatgg cgtgccgcgt agtcacgggc ggcacgcaaa
    20281 gtgcatttat aagaacccgt acatcgcggc gaagatccag ccgaagacgc acgatacgct
    20341 cacaccaatc aaccccggca gaataaagct gtggttgatg acgaagcgac cgatgtgggt
    20401 ggtgccggaa cggtcaaact gaatcgctgc cagatcgctc ggataagtcg gcaggatgta
    20461 ataaccgtag caagccggtg ctgaagccac gatgtatgcc ggatcaacgc cgatcgccag
    20521 cgcgaccgga acaatcgccg ccagcgccgc agcctgagag tttacaaact tggaaaccag
    20581 cagcagaaca atggcatagg cccacggata ctctttcacc atttcaccca gtacgccctg
    20641 aatttcagac atatgcgcac cgaacatggt ttctgccatc catgcgatac cgtacaccgc
    20701 cacgatggcg atcataccgg aacggaagac ttcgtttttt gagatagacg cgggattggt
    20761 tttggtcagg ataataatca gcgccccggt cagcagcata aacatctgaa taaccagtac
    20821 catcgacagc ggtttgccgc cgaaggatgg acgcaggtcc gaatcagcac caagaagggc
    20881 gactacagcg attgccccga ggaaaatcca cattgccagc cagttgcttt tcggcagttt
    20941 tttatccagc agcgtcgcgg tatcaccgta aacatactca cggttttccg gtacggagat
    21001 gaatttctgg aactcttcgt ctttatccag atctttaccg cggaaccagc tgaagatacc
    21061 gatcgccagg ataccgatta acgtcgatgg aatggtgatt gccagcagat cgaggaactc
    21121 aagatggcga ccatcaaagg tgacattacc cagcatcgca accagagaca cgaccgcaac
    21181 cgacaccgga ctggcgataa tccccatctg tgcaccgata gaacttgccg ccatcggacg
    21241 ttccggacgg atgttgttct taatggcgac gtcgtagatg atcggcagaa tggtgtaaac
    21301 cacatgaccc gtaccgcaaa gaatggtcag tgtacaggtc acaaacggcg cgacaattga
    21361 gacatatttc gggttgcggc gcagcagctt ctcggcaatt tgcagcatga catcaagacc
    21421 gcccgaagct tgcaaggtcg ccgatgccgc caccaccgca atgataacca gcatgacatc
    21481 aactggtggt ttacctggct gaaggtggaa gacgaagacc agaatgacca gaccgatacc
    21541 gcctaataaa cccagcgcga taccaccctt tctggcacca taaaacagac atatcagtat
    21601 tatgataagt tggatagtaa ataacatgtg tgaaccctcg cgataatcct atttaaattt
    21661 ttgctgaata gatcacagtc acgttctgtt ttgtatgaac tgttttcaga gcctgactaa
    21721 atatccgttt ggtcgttacc ggctttagca aatacctcac agtgaatatt ggctgattaa
    21781 agcagcggca aatttatgca ctgtgataag cggctttttc agagagaaag actctctggc
    21841 gatgggttta tagtttgtac tgcgcagatg ttaatgtttt gtttgctgtt atcttattga
    21901 tatttatcgg tctatttttt gttctcaggg cagatgtcat taggtttata gattaatctg
    21961 atctacccat ttgtgggtaa aaatacacat aatgcgggtg acataatagt taattaactt
    22021 ttgttagcgt tttgaaatta aaaacaccgt tcacctgaag agatattaat ttttagcgat
    22081 gatggaggga taattatatt tgatctggca caagttttac tgatgaagga tgtaacttgt
    22141 gccaggggta ttttgcatta cggtaataat tattacttac agataaccag cgatccgtta
    22201 ttggcaatat tgtttcagta gtgagtagtg ttctgcctga atacggtaac ggtaaactgg
    22261 acgccccgtg acgccataat ggatactggt gaacaagatg tggcagttga ccagccagat
    22321 gaggtattta cggcaggaaa cacgcgaaat gttaacctcg ttggctagct cgtcggttga
    22381 aaattcatag tcctgatgcg cgtcaatcca ctggcacagt gtgcgtaacg tctgcggcgt
    22441 taagcctttt ggcaagcgac gaggatcctg ttcgttggag ctgctgccgt ggattagctg
    22501 atcaagctcg gcctggtcat aatactgatg tttttccagc gccattttct tttgccgcca
    22561 gccggtgagc gcctcttcaa agcgggaagc ctggaagggt ttgatcaggt aatccacgac
    22621 accgtaatgc agcgaatctt taatggttgc cgcatcggct gcggaggaga tgacaatcac
    22681 atcacttttg caacgcgcgt tatgcaggac aggcagtaaa tcgagcccgt tctctttttg
    22741 catatagata tcgagcaata tcaggtcgat aggcgtatcg ctattgaaga taatctcttt
    22801 ggctttctcc agcgtcgagg ctgttccaca gcattgaaag cctgggattt gtgctacgta
    22861 tcggcgattc agctccgcga ccattgcgtc gtcatcgata attaatacat tgatcatctg
    22921 ttcgacctct ccccgtccca gggtatctgg acaaaaaatt gtgtgaaaat cccgggttcc
    22981 gattccacgg cgatgctgcc gccgagattt tctacctgtt gtttgacaag tgctaaaccg
    23041 acgcctcgct cgcttccttt tgtcgagaca cctttgtcaa aaatgtgatc gattttatcg
    23101 ggtgcgatcc ccggtccatc atcattaact tcacagtgca gccagccgtg acggtagtgc
    23161 aatgttacgc taatttcgcc tccgggttcc ggccctaatg cctccagcgc gttttctatc
    23221 agatttccca acgtggtaat cagcgtcgcg acctggtcct cactgccgct gtctggcagc
    23281 tggctttcac tgtttaaaat cagcgtatgg cctaaatcgg tcgcgcggtt aatcttgctg
    23341 attaaaaaac cagcgataac cggagatttg atcttaccca gcagagagcc aatctcttcc
    23401 tgatagttat tggctgtttt gagaatgtaa tcttccaact gcttataact cttcagatgc
    23461 aataatccga gaatcacatg caatttattc ataaattcgt gggatcgttc acgaagtgcg
    23521 tcagcatagt tgaccagacc gtcgagtcgc tgcatcagtt tacgtacttc agttttgtcc
    23581 ctgaaggttg aaatggcacc gatgataacg ccattactgc gcaccggaac ggtgttgatc
    23641 agtaatagcc ggtctttaat cgtaatctct tcgtcgcggc gcggggtacc gtcgcgtaac
    23701 acttccgaga catctaccac ctgtgaccat gagtggctta gcgtcgacag tttctcatcg
    23761 tcctgcgact tacggtaatt cagcaattct tgtgcggcat cgttgatcag cgtgacctcg
    23821 ccgcgatcgt ccacggcaac gacgccttct ttgatagact gcaacatggc ctggcgttgc
    23881 tcaaacagcg tggagatttc gtagggttcc aggccgaaaa ggattttttt cagtacctta
    23941 accagaatgc aggtgccaat cagtccgacc agcatgccaa ataataccga ccagataatg
    24001 ctccagcgac tgtcattgat ctgttgggtc acacggctta actcaaggcc gatcgccacc
    24061 acgccaattt gtttatgatt ttcatcgtag atgggggtaa atacgcgtaa agcctgcgcc
    24121 agaaaaccgc gattgatagc gacattttct tcgccattca gcgctttaag gatgtcatca
    24181 cctttaaatg gctgaccaat acgctgggct tcaggatgcg agtagcgaag actttgcata
    24241 tcggtaacga caataaacag cagatcgttg cgtttgcgta cggcttccgc gatggcctgg
    24301 atgccactct cctgcggttt tttctgcaag ccctgacgga tttccggcga gtcggcgagg
    24361 gtacgcgcca ctgccagtgc cttgttggct agcccatctc gcgtcatatc actgatttgc
    24421 gagaagtaaa tcagatgcac caccaatagc accgagaaca gtaccgcact gaccattaag
    24481 atcactgtgg tactcaattt catcggacgt ttgcgtaaca tgcggtaggg caatgaatgt
    24541 ctcatcagct tccttgtgtg acaaatttct taagcattat ctctgatgag gcgggtaatt
    24601 caaagggagt aagaatgatt ggctatatag gggaagagac tctggcaacg gaaactgcca
    24661 gtgctgtatg aagattccgg ggctatgctt atagcgataa tcatactgat gagagaggga
    24721 aggtcatgga tcaggcgcta ctggacgggg gttatcgctg ttataccggc gaaaagatcg
    24781 atgtctattt caacactgcg atatgtcagc attctggcaa ttgcgtacgt ggcaacggca
    24841 agttatttaa tctcaaacga aagccgtgga tcatgccgga tgaagtcgac gtcgccactg
    24901 tggttaaagt gattgatacg tgcccgagcg gcgcgctgaa ataccgtcat aaataagcga
    24961 gggtaaaatg gaaatacgcg aaggccacaa taaattttac attaatgaca aacaaggcaa
    25021 gcaaatcgct gaaattgtct ttgtgccgac cggagagaat ttagcgatta tcgaacatac
    25081 cgatgtcgat gaaagcctga aagggcaagg gattggtaaa cagctggttg cgaaagtcgt
    25141 ggaaaaaatg cgtcgggaaa aacgaaaaat tatcccatta tgcccatttg cgaaacatga
    25201 atttgataaa acgcgggagt atgatgatat tcgcagttga tgggagagta cagagtcacg
    25261 atatttttca ttctctccgc gatgtgatgc aggagagcat ctgaagggta gggggatgca
    25321 caaagaatgg gcagagagcg cgtttttttg tcccaagtca tcccctttac tgagcaaaaa
    25381 aaagaatatc tcctatatga gaatcatcaa tcggggttaa taagttttgc gtccccagag
    25441 cgtttaatat tgataggagt catattatgg aaggtaaaaa caagttcaat acttatgttg
    25501 tttcttttga ttatccatca tcttattcct cagtgttctt aagattaaga tcattgatgt
    25561 atgatatgaa tttctcctct atcgtggctg atgaatatgg gataccacga caattgaatg
    25621 aaaactcctt cgcaataacg acatcgttag ccgcaagtga aatcgaagat ttaatcaggc
    25681 tcaaatgctt agacttaccg gatattgatt ttgacctcaa cattatgaca gttgatgact
    25741 atttccgtca gttttacaag tagccaggaa ggataagaag aacataaaaa atggcactat
    25801 tctctaaaat attaattttt tatgtgattg gtgtgaacat atcctttgtc attatctggt
    25861 ttatctcaca tgagaaaaca catattcgtt tacttagtgc attcctggtc ggaataacct
    25921 ggccaatgag tctgcctgtg gcattacttt tttctctctt ttaggagctg tagttgagtg
    25981 gacccgctgg ttatcgtgaa acgaagcgtc tctcctcaaa actggatttg cggaacgatg
    26041 aacgaagcag tcgcctgact gcttcgttca ttaaagtgaa atttatttct gtgggcgcat
    26101 cgccgggaag agaataacgt cgcgaatagt atggctgtta gtaaacagca taatcattcg
    26161 gtcgatacca atacccagac cagcggttgg cggcagacca tattccagcg cagtcacgta
    26221 atcttcgtca tagaacatgg cttcgtcgtc acctgcagct ttagcattaa cctgttcctg
    26281 gaaacgttca gcctgatctt ctgcgtcgtt taattcgcta aaaccattac cgatttcacg
    26341 accaccgatg aagaattcaa aacggtcggt gatttccggg ttaacatcat tacggcgtgc
    26401 cagcggggac acttctgccg gatattccgt aataaaggtt ggctgaatca gatgtgcttc
    26461 tgccacttca tcaaagatct ctgtgacaat acgtcccaac ccccagcttt tctctaccgt
    26521 aataccgata gattcagcta atgctttagc agcatcaaaa ttatccaggt cggccatatc
    26581 ggtttctgga cgatattttt tgattgcttc gcgcatggtg agtttttcaa acggtttgcc
    26641 gaaatcaaac acatgctcgc cataagtgac tttagtggta cccagaacct cttgtgccag
    26701 ggtgcggaac agtgactctg tcagttcaat caaatcgtgg taatccgcat acgccatgta
    26761 gagttccatc attgtgaact caggattatg gcgaacagaa ataccttcat tacggaagtt
    26821 acggttgatt tcgaataccc gttcaaaacc gcctacaacc agacgtttca gatacagctc
    26881 cggcgcgata cgcagataca tatctaaatc cagagcatta tgatgggtaa taaacgggcg
    26941 agcagatgcc ccacctggaa ttacctgcat catcggggtt tctacttcca taaagccgcg
    27001 cgcgaccatg aattgacgga tagcggccag aatttttgaa cggacaacaa acgtttgacg
    27061 ggatttatcg ttagcgatga ggtccagata acgttgacga taacggactt cctgatcctg
    27121 cagaccatgg aatttatctg gtaaaggacg tagtgcttta gtcagcaggc gcagctcagt
    27181 acagtgaatg gaaagctcac ccgtttgcgt cttaaacagc gtaccgcggg caccgataat
    27241 gtcacccaga tcccattttt taaactgatc gttataaaca ccttctggca ggctatctct
    27301 tgcaacgtac agttgaatac ggccaccgac atcctgcaac gttacaaagg aggctttccc
    27361 catgatacga cgggtcatca ttcggccagc aaccgagact tcaatgttta aggattccag
    27421 ttcctggtta tccttcgcat caaactcttc gtgcaactgg tcagaggtat ggtcgcggcg
    27481 aaaatcattg ggaaacgcca caccttgctg acgtagtgcc gccagttttt cgcggcgatt
    27541 tctcagttca tcgttaaaat caatagcctc attggctccc cgtgtttctt gttcagacat
    27601 tttggttcct ctaaatccag ctttcaattt agcgtagata aagagacaga tcggtacact
    27661 gtattatctg cctcgactat tagtaactca gtttatctta tcgaaactaa cgcttacctc
    27721 aagttgatat cactaataaa taaccatcaa aatggtttaa atgacttatt aatctcgatt
    27781 tgttagtgtt ataaactgaa agttaattta ttcataacca attgttttta cgacagttaa
    27841 tcgttgctct cctgtatcat attcgtcggc gtgctaaaca gaaaacgggt agcaaaggcc
    27901 aatacgacga tgatcgcgac acaagccaac gtccactctc ccatctgaga aaagaatcgc
    27961 tggtaagctg caattgccat accgctaatt tgcgactctg tcgtctgctg tgccacgacg
    28021 cctgccagcc agttggcgac cgcgcctgtt gccagcatat aaatcccggt taatacgcca
    28081 gacattttca gacgcgtgat ttgcgcaatc gccaccgggt caataaagag ttcggcaaag
    28141 cccattagcg ccagcccgga tatcatcacg cccattgacg cttgaccgtc agccgctgca
    28201 tgtcgggcat caaatgccaa caacataaag ccacaagcca tcagcagtaa gccaaaggca
    28261 aacttcagcc agacgcgcaa tgttgagttg ccgcggcttt ctggcgacgc cagccaggcc
    28321 agtacaaccc cagcgagcat caccgcaatt gcattcaccg actggaatag tgctgtaggt
    28381 acttcaatat tgaatgcctg acgattcaca aagcgatcga taaacaagct gatggtactg
    28441 ccgccctgtt gtgccagtac ccagaacaat gtcccgacaa acatcaacaa tacaatttgc
    28501 caaagagcac ggcgatgttc ggggaatttg atcatcatgc gggcaatgat ttgtgcggca
    28561 atgaggcaaa cgatcgccag caaatatccg gaccagtcgt tctccagcag cagagtaaaa
    28621 aatactgggg ctaaacagag cattaccact aaccagctcc atactggtaa ggcaaatttg
    28681 acactagtga gcgctttttt atccatacta cgtgtggact ggaaatgacg atgaccgctt
    28741 aagaaaatca acaaaccgat aaacatgccg ccacccgcaa gggcaaagcc aacatgccat
    28801 ccataccact gagcagccag gccgcaggcg attggggctg cgatagaacc gatattgccc
    28861 gcagcataca gcagcgaaaa accgccatca cgtcgatgat cgttctcgtc gtagagctcg
    28921 ccaagcaaac agctgatgtt tgatttgaat aaaccgtagc cacaaataat gattgccagc
    28981 gccagataca ggctaaaggt tgaatttgta tcaataccca gcaccacatg gccaagggtc
    29041 attaacagcg cgccggcaat cactgcagtg cggttgccga gcaggcggtc ggcaagccag
    29101 ccgccgagaa taggggtaac gtaaaccaga gaagcatatg cgctgaacag gctgatggca
    29161 tggttatcat caaaaccaag ctgatgggtg agatagagaa tgagtaaggc acgcatgccg
    29221 taaaaactga agtactccca gatttggatc gccacgatat agtatatcgc gcgcggctgt
    29281 gagggtgttt tcatgtgttc tccttatgag caaaaaaggg aagtggcaag ccacttccct
    29341 tgtacgagct aattattttt tgctttcttc tttcaatacc ttaacggtat agcggccatc
    29401 agcctgacgg tatgcaccgt gaatatcggt ttcaaagccc ggatagtgag cgccgatttc
    29461 acacagcatc tgcaggaact ccagaaccgg acggctttct tcggtgatca tttcacccgg
    29521 cattaccaga ggaactcccg gcgggtacgg aaggatcata ttggcgttaa tacgacctac
    29581 catttcgtcg aggtaaactt cttcggtcat accgtgcagc tctttctgga atgcagcata
    29641 cggagtcatt accatcgtcg gcagcacttc aaatgcgcga tacatcagat ccggcagatt
    29701 gtggtgaaca atcagtttgt ggatattctg agccagttcc tgaatacgca tgttttcata
    29761 gaattcagga tcttcacgat acagagacgg cagcatgttt ttcacacgca ggttcaggtc
    29821 gaacgcacgt ttaaagtcag tcagagcacg cagcaggctc agtgctttgg tcttatcgat
    29881 accgatgctg aacaggaaca gcaggttata cggaccggtt ttctcaacaa cgatgccatg
    29941 ttcgtcgagg tatttcgcca cgatgctggc cggaatacca aagtcgctca tggtgccgtc
    30001 tttttccatc cccggagtca gcagggtgac tttgatcggg tcaagataca tgtgctcgtt
    30061 atcgatgttt ttgaagccgt gccaggtgct gtcagaacgc agcggccagc attcagtcgt
    30121 atcgatatga tccggctgcc atacatcaaa gaaccagcca tcagattccg ttctcagacg
    30181 tttgatctct ttacggaatt tgatcgcacg ttcaatagaa ccgttgatca gacgcttacc
    30241 tgcattgcct ttcatcatcg ccgcagcggt ttcagtggac gccacgatac cgtagtgcgg
    30301 agaagtggtg gtgtgcatca tgtaggcttc gttaaaggtt tcttcgttta cgtcaccttt
    30361 aacgtggatc atggaagcct gagagaacgc cgccagcagt ttgtgagtgg actgggtttc
    30421 gtaaatcact ttcccttcta cacggccacc gctcataccg catttacctt cgtaaatcgg
    30481 tgagaagttg gtgtaaggca cccacgcgga gtcaaagtgg atggatttca catccagtgt
    30541 tttcttgatg aagtcggtgt tgtacagcag accatcatag gtagagttgg taattacagc
    30601 atgtaccggc caggttgcgt ttggtgtttc tttcacgcgc ttagcaatgg tagcgtgctg
    30661 gaattcactc tgtgggatac caccaagaat accgtaagcg ttacgggtcg ggcggaaata
    30721 gattggcgta acatcgctca tcatcatcag gtgggtcagc gatttgtggc agttacggtc
    30781 aatcagaatg gtgctgcctg ctggagcaga gtacatacca acaattttgt tcgcagtgga
    30841 agtaccgttg gtcaccatgt agctgcggtc tgcgttaaag acgcgagcga tatactgttc
    30901 tgcttctttg tgtggaccac tgtgatccag cagagaaccc agttcagata ctgaaatgga
    30961 aatatcagat ttcatggtat tcggaccaaa gaaatcatag aacaggctac ctaccgggct
    31021 tttctggaat gcagtaccgc ccatgtgacc aggagtacag aaagtatatt taccttcacg
    31081 aacatattta aacagtgctt tagtcagcgg aggcagaata gtgttgatat attcgtcagt
    31141 ggtctgcttg atcttattag caatatcttc agcagcaccc agcgcatatt caaagaagct
    31201 aatctgtaaa cgcaggtcat tcaggcttac atcgagagtg gaatacgtat tagcgaacgc
    31261 gtacaacggc aggttctcgt tcattttgct aatttcttcg cacagctcga gattatattt
    31321 atcccagtca aaaataacgc cgcacagacg cgcattgttt tcgatcagtt ttaataagtc
    31381 gtcacggtcg ttcgggtaaa caatctggaa gttcagacgt tcaagcgcgc gatgaagttc
    31441 acggatgggt tcttctttaa aataaacccc catgtgattc aatattgcaa taacgttcat
    31501 agtcatatct ccaggtaaaa aaggtccctc ccaacacatg ggacaaaatg aaaggaggag
    31561 cctcggaaaa tacttttaat taatgtgcgt tagacgcggt gtggttatcc attgagtggc
    31621 tctggcgctc gtgcattttg cgagcgtaga acatcaggat aatcaggctg acgatgaagg
    31681 tacctgccag ctcgaaggag cttgcgccca tcagcgcgat gaagcagaac acgcaaccca
    31741 gtacagagca gatcaggctg acaaagttgc ggatgttaac gccttcaaaa cgaatcaggt
    31801 caacgcaaga gtagaaatac ggcagcatag tcagcagtac tgcgataccg gtcagttcac
    31861 cgaacaggtc agatgcttta ccaccggcag agttcatcag agtgataagg atcatcaggg
    31921 cagtcatttt cactgcagcc agcagcagac cttttttcgg aataccgttg ctgtcgactt
    31981 caccataaac tttcgggaag ttaccgtcgt tagcggcacg tacacctgcc tggcctacca
    32041 acatcatcca ggagcccaga gaagtcaggc acgcaaaggc ggtgaatgca gaaaccagcg
    32101 gcgcagccca gttaccgagg atagttgaag cactgattgc aaacggagca ccggaagccg
    32161 ccattacaga agacggatac ataccggaaa gcacctgagt cgcagcgatg taaacaatac
    32221 ctgctaaacc agtacccagc atggttgcca gcggaacggt acgtttcggg tttttaacca
    32281 taccagtact tacagctgcg gattcaacac ccacgaaggc ccacaggcag agcagaatac
    32341 ttttaatgat cgcatgacca tcagtggtat ccgcagtatt ccagttagct gcataagttg
    32401 ccgcatcaaa ccaatgccag ccaacaatag cagtcatcac cacaggaata agaaccagca
    32461 ccagaccaat agtggttaaa cggcttaccc aagtaccgcc gagcatattt acaaaggtaa
    32521 atacccagac gatagcaata caggcgatac ccgccggaac aggatcattt aatactggga
    32581 agaaggtgga aagataagat acagcggtaa taccaatcgc caggttacca atccagttag
    32641 catggtaata aagaacacct gtctgaaaac caaatgcagg ggaaatttct ccggcataag
    32701 caattgggcc accttgttgc gggttttttg ttgccagtcg ggcatataca tacgccagcg
    32761 acattgcacc aataatagag ataatccaac cccagatagc aataccaccg atacttgcta
    32821 ggttcgcagg taataatgca ataccgctcc ccatcatatt accggcaaca acaccggtac
    32881 aggcaaatag cccgatcttc ttggcagaac tcatgctctt ctcctaattt catttttgaa
    32941 tttggagtcc gggtcatgat gtataactat ttcctgacca gaccaaactg gcgataagat
    33001 tactcacgaa aaaaggatta atcctaaaga ttaggtgaaa taacacaaaa gtttctgtaa
    33061 gtgagaactt gaggtttttt attaacacat caggatcgca agttgatatc atgaaaagat
    33121 aaacatttaa tgtttacaat ggattgcgtg acattctctg gttaaattta tgtaataaaa
    33181 attatgcggc aaataaattg ccgcaacata ttataccaac aggaacatac aaaaactcaa
    33241 caacaaatat ttccgagcat aaatcaaccc ggagttactt attctgaagc aagaaatttg
    33301 tcgagataag gtacaacata aggaacagaa gtctggaata taccattttc aatccagtaa
    33361 agggtgtttg cccctgggcg taaattaaag gcggtgagat atgcatcagc tgcttcccgg
    33421 ttcatcccct tcatttcata aaccttgcca agcaacacat aatttagcca ggacatttca
    33481 agatcaatgc cagtatttat cgcctggtaa gactcatctg ttttaccttt taccagagca
    33541 ctgaccgctt ttatttgata tataatggac aggttgttca attccggcag tgtaacaatg
    33601 ttatctattt ctgtgttcag tgctgctaat tgtttttcat ctaaaggatg ttgagaatgg
    33661 cgcacgatat caactaatgc tttttctgct ctcgcgtagg taaattctgg ggatgattga
    33721 acaatctcac ctaataattc actggcacgg ttcaatgatt tatcatcgcc atgcagtaaa
    33781 taatcatgtg cctgataaaa attagttaat aacgcaccac gatgcggcaa aattttctgg
    33841 agcgtctcct gcattcgttg tggccacggt tggtttaacg cttttgataa actctccagt
    33901 aaatcatttt gaatcgccag ctgattaccg ttagtgatga cataacgttt atccagcatg
    33961 gttgaaccat ctgcattgtc taccaatttt atcgacataa agcattgttg agcacggtat
    34021 tggcgctgat taacaaacgc aatagataat gttttaccgg aactgctcgg ttcatcaatg
    34081 ttgtagttga ttttgtcatg caccataaag gtggagaagg tgttaagtga tgtcgccacc
    34141 aaatcaccca cgcctatcgc gtaagagagc tgatacgggg aactccagct gttacaactt
    34201 ttatttacca tattaatgtc aatatcgcgt ggattgagca aaatacgcga tttgctcata
    34261 ggaagacgtg tatcaagact tgaaaacgct accagtgcta cacagatacc taacgacaac
    34321 aggaaaaaaa accataccca aaaggtagtg aatcgtttgc ttttaactgg ggattgttca
    34381 ggtggcgttg cggtgttttg aatgttaaga ctgtgggagg gagaatctgt ggcaggaacc
    34441 gcctctggta tagggggagg cgaagatagc attatttcct ctccctcttc ttcgctgtac
    34501 cagataaccg gcaccattaa tttatagccg cgctttggta cagtagcgat atagacagga
    34561 ctatcttcat cattatcttt taatgactta cgtagttctg agatactctg cgtcacaacg
    34621 tgattggtga caatacttct cttccagaca ttatcgataa gttcatccct gctaagtact
    34681 tcgccactgt gttgagcaaa gaaaaccaga agatcgatta atctcggctc aagggtaagt
    34741 tgacgcccat tgcggctaat ttggtttatg gacggagtaa caagccattc gccaacgcga
    34801 actacaggtt gttgcataat agaaactcat tcgaaaaggg aatgatgcaa tgataattgc
    34861 cacaacctat ttttaccatc tatagatggg tttatttaca tattattggt gaatgcaaga
    34921 cgttattttt accagccata aacttcttga ttacatagta ttacgaaagg attttactga
    34981 gaaccagaag taatattcct taccatcaaa attcatcatc tttgccaaag aaaaatgttc
    35041 agaaaataat ccatggaaaa ttgtccggag cacttactat tttaatggat tgttagtctt
    35101 tgcatgagca agcgaactga tacatttctc tttgttctca ttcagaaaat ctcatcagtc
    35161 gccgttcaga ccggtgttgt gctttatgga tgcgttacgc tcctgatgac gtcatttgac
    35221 gttcaacagc atcacggggc cgcacgacat ttcacgtcag ttagtgctat agctcaggaa
    35281 caaattttcc cgaattggga tatgcccgca aattgctggt gatgtgggga gaatctggtt
    35341 gagttcggta gaattgattt ggaggcagaa cgcttaaatc gtggcgtcct gaaacgaaaa
    35401 acggacctcc gtggaggtcc gtttatatga atttg
//
LOCUS       DACAOP010000043        34609 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.043, whole genome shotgun sequence.
ACCESSION   DACAOP010000043 DACAOP010000000
VERSION     DACAOP010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34609
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.043"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(23..748)
                     /gene="phoU"
                     /locus_tag="IT892_002326"
     CDS             complement(23..748)
                     /gene="phoU"
                     /locus_tag="IT892_002326"
                     /EC_number="3.5.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAP3135538.1"
                     /translation="MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMH
                     NQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERI
                     GDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
                     DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVK
                     GQDFRHVGGDELDKLLAGKDSDK"
     gene            complement(763..1536)
                     /gene="pstB"
                     /locus_tag="IT892_002327"
     CDS             complement(763..1536)
                     /gene="pstB"
                     /locus_tag="IT892_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HAP3135539.1"
                     /translation="MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGP
                     SGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNSQDIALLRAKVGMVFQKPTP
                     FPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
                     RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARC
                     SDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG"
     gene            complement(1719..2609)
                     /gene="pstA"
                     /locus_tag="IT892_002328"
     CDS             complement(1719..2609)
                     /gene="pstA"
                     /locus_tag="IT892_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAP3135540.1"
                     /translation="MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFW
                     LIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLANALAGSGLLILWATVFGTPLGI
                     MAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL
                     ALLQVPIVIRTTENMLKLVPYSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAI
                     ARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIIT
                     LCVLLLNILARVVFAKNKHG"
     gene            complement(2609..3568)
                     /gene="pstC"
                     /locus_tag="IT892_002329"
     CDS             complement(2609..3568)
                     /gene="pstC"
                     /locus_tag="IT892_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HAP3135541.1"
                     /translation="MAATKPAFNPPGKKGDIIFSVLVKLAALIVLLMLGGIIVSLIIS
                     SWPSIQKFGLAFLWTKEWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTE
                     LAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFAVYFQEPVGNIMSNIPIVGAL
                     FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRI
                     VLPFTKNGVIGGIMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFA
                     EAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR"
     gene            complement(3655..4695)
                     /gene="pstS"
                     /locus_tag="IT892_002330"
     CDS             complement(3655..4695)
                     /gene="pstS"
                     /locus_tag="IT892_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAP3135542.1"
                     /translation="MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKW
                     ADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIG
                     GVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRR
                     ADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGY
                     VEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWP
                     ITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWK
                     TNIKDSSGKPLY"
     gene            complement(5009..6838)
                     /gene="glmS"
                     /locus_tag="IT892_002331"
     CDS             complement(5009..6838)
                     /gene="glmS"
                     /locus_tag="IT892_002331"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAP3135543.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGII
                     ENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTV
                     IMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
     gene            complement(7000..8370)
                     /gene="glmU"
                     /locus_tag="IT892_002332"
     CDS             complement(7000..8370)
                     /gene="glmU"
                     /locus_tag="IT892_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAP3135544.1"
                     /translation="MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAAN
                     ELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQ
                     RLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDT
                     NVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRP
                     GAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWR
                     RPVKKK"
     gene            complement(8722..9141)
                     /gene="atpC"
                     /locus_tag="IT892_002333"
     CDS             complement(8722..9141)
                     /gene="atpC"
                     /locus_tag="IT892_002333"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAP3135545.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKA
                     EEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM"
     gene            complement(9162..10544)
                     /gene="atpD"
                     /locus_tag="IT892_002334"
     CDS             complement(9162..10544)
                     /gene="atpD"
                     /locus_tag="IT892_002334"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAP3135546.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     EEAVEKAKKL"
     gene            complement(10571..11434)
                     /gene="atpG"
                     /locus_tag="IT892_002335"
     CDS             complement(10571..11434)
                     /gene="atpG"
                     /locus_tag="IT892_002335"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAP3135547.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRP
                     YAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAE
                     MKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(11485..13026)
                     /gene="atpA"
                     /locus_tag="IT892_002336"
     CDS             complement(11485..13026)
                     /gene="atpA"
                     /locus_tag="IT892_002336"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAP3135548.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(13039..13572)
                     /gene="atpH"
                     /locus_tag="IT892_002337"
     CDS             complement(13039..13572)
                     /gene="atpH"
                     /locus_tag="IT892_002337"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAP3135549.1"
                     /translation="MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAV
                     SEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(13587..14057)
                     /gene="atpF"
                     /locus_tag="IT892_002338"
     CDS             complement(13587..14057)
                     /gene="atpF"
                     /locus_tag="IT892_002338"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAP3135550.1"
                     /translation="MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(14119..14358)
                     /gene="atpE"
                     /locus_tag="IT892_002339"
     CDS             complement(14119..14358)
                     /gene="atpE"
                     /locus_tag="IT892_002339"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HAP3135551.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(14405..15220)
                     /gene="atpB"
                     /locus_tag="IT892_002340"
     CDS             complement(14405..15220)
                     /gene="atpB"
                     /locus_tag="IT892_002340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAP3135552.1"
                     /translation="MASENMTPQDYIGHHLNNLQLDLRTFSLVDPQNPPATFWTINID
                     SMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFIL
                     ILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(15229..15609)
                     /gene="atpI"
                     /locus_tag="IT892_002341"
     CDS             complement(15229..15609)
                     /gene="atpI"
                     /locus_tag="IT892_002341"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HAP3135553.1"
                     /translation="MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGG
                     LAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
     gene            complement(16226..16849)
                     /gene="rsmG"
                     /locus_tag="IT892_002342"
     CDS             complement(16226..16849)
                     /gene="rsmG"
                     /locus_tag="IT892_002342"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAP3135554.1"
                     /translation="MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVR
                     DPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRV
                     RFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGR
                     FYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI"
     gene            complement(16913..18802)
                     /gene="mnmG"
                     /locus_tag="IT892_002343"
     CDS             complement(16913..18802)
                     /gene="mnmG"
                     /locus_tag="IT892_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAP3135555.1"
                     /translation="MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQ
                     MSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRV
                     LYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLD
                     GKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQ
                     HGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRY
                     CPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENA
                     KIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAA
                     RLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTE
                     IGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREAS
                     GEDLLRRPEMTYEKLTTLTPFAPSLTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE
                     NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM
                     LRRSA"
     gene            complement(19181..19624)
                     /gene="mioC"
                     /locus_tag="IT892_002344"
     CDS             complement(19181..19624)
                     /gene="mioC"
                     /locus_tag="IT892_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein MioC"
                     /protein_id="HAP3135556.1"
                     /translation="MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDL
                     PASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAI
                     DKLEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWVNLLK"
     gene            complement(19714..20172)
                     /gene="asnC"
                     /locus_tag="IT892_002345"
     CDS             complement(19714..20172)
                     /gene="asnC"
                     /locus_tag="IT892_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator AsnC"
                     /protein_id="HAP3135557.1"
                     /translation="MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVE
                     KMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTT
                     GHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP"
     gene            20324..21316
                     /gene="asnA"
                     /locus_tag="IT892_002346"
     CDS             20324..21316
                     /gene="asnA"
                     /locus_tag="IT892_002346"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HAP3135558.1"
                     /translation="MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGT
                     QDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPD
                     EDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPF
                     LPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDY
                     DDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLEL
                     EWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL"
     gene            complement(21321..22772)
                     /gene="viaA"
                     /locus_tag="IT892_002347"
     CDS             complement(21321..22772)
                     /gene="viaA"
                     /locus_tag="IT892_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /protein_id="HAP3135559.1"
                     /translation="MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKA
                     AITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRL
                     NSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQ
                     ERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQ
                     LGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELATLGITE
                     LEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGG
                     FNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGG
                     TDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVA
                     MSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR"
     gene            complement(22766..24262)
                     /gene="ravA"
                     /locus_tag="IT892_002348"
     CDS             complement(22766..24262)
                     /gene="ravA"
                     /locus_tag="IT892_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418202.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /protein_id="HAP3135560.1"
                     /translation="MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFL
                     LGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTS
                     GYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGAHVEKIPMRLLVAASNELPEA
                     DSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPDALQVTDEEYERWQKE
                     IGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVTPVD
                     LILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKT
                     ALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERSALEQWLS
                     KGGEIRGKLNGIGFAQKLNLEVDSAQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQL
                     EELESDWRKQHALFSEQQKCLFIPGDWLGRIEASLQDVGAQIRQAQQC"
     gene            24485..26353
                     /gene="kup"
                     /locus_tag="IT892_002349"
     CDS             24485..26353
                     /gene="kup"
                     /locus_tag="IT892_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /protein_id="HAP3135561.1"
                     /translation="MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGV
                     ERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSML
                     VIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVSLSIIVLTLLFMIQKH
                     GTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIAL
                     GAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNP
                     FFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMES
                     GQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHW
                     NKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRR
                     MHEHGNSLEAMIASLEKSPPARVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILL
                     TLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMME
                     TSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI"
     gene            26520..26939
                     /gene="rbsD"
                     /locus_tag="IT892_002350"
     CDS             26520..26939
                     /gene="rbsD"
                     /locus_tag="IT892_002350"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAP3135562.1"
                     /translation="MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMAL
                     TQGVPSFMQVLGVVTNEMQVEAAIIAEEIKHHNPQLHETLLTHLEQLQKHQGNTIEIR
                     YTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF"
     gene            26947..28452
                     /gene="rbsA"
                     /locus_tag="IT892_002351"
     CDS             26947..28452
                     /gene="rbsA"
                     /locus_tag="IT892_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /protein_id="HAP3135563.1"
                     /translation="MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKS
                     TMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFL
                     GREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFES
                     KVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQ
                     FIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLR
                     KGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLANGIVYISE
                     DRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQA
                     IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIIL
                     VSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE"
     gene            28457..29422
                     /gene="rbsC"
                     /locus_tag="IT892_002352"
     CDS             28457..29422
                     /gene="rbsC"
                     /locus_tag="IT892_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002882531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HAP3135564.1"
                     /translation="MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTIN
                     NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVA
                     AALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
                     FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNK
                     IKIIIYSLCGLLASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIV
                     GTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ"
     gene            29447..30337
                     /gene="rbsB"
                     /locus_tag="IT892_002353"
     CDS             29447..30337
                     /gene="rbsB"
                     /locus_tag="IT892_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /protein_id="HAP3135565.1"
                     /translation="MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSL
                     KDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKM
                     ANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
                     SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAIFAQNDEM
                     ALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKV
                     LKGEKVQAKYPVDLKLVVKQ"
     gene            30463..31392
                     /gene="rbsK"
                     /locus_tag="IT892_002354"
     CDS             30463..31392
                     /gene="rbsK"
                     /locus_tag="IT892_002354"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAP3135566.1"
                     /translation="MQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKG
                     ANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFV
                     NGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNK
                     TIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIR
                     TVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKPLPEAIR
                     FAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR"
     gene            31396..32388
                     /gene="rbsR"
                     /locus_tag="IT892_002355"
     CDS             31396..32388
                     /gene="rbsR"
                     /locus_tag="IT892_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /protein_id="HAP3135567.1"
                     /translation="MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELN
                     YAPSALARSLKLNQTHTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQ
                     RMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
                     SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTG
                     DFEFNGGFDAMRQLLSHPLRPQAVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDI
                     ELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQLTPILMERGSA"
     gene            complement(32354..33781)
                     /locus_tag="IT892_002356"
     CDS             complement(32354..33781)
                     /locus_tag="IT892_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3135568.1"
                     /translation="MSDKKKRSMAGLPWIAAMAFFMQALDATILNTALPAIAHSLNRS
                     PLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRIFTLAVSLFTLGSLACALSNSLPQL
                     VVFRVIQGIGGAMMMPVARLALLRAYPRNELLPVLNFVAMPGLVGPILGPVLGGVLVT
                     WATWHWIFLINIPIGIAGLLYARKHMPNFTTARRRFDITGFLLFGLSLVLFSSGIELF
                     GEKIVASWIALTVIVTSIGLLLLYILHARRTPNPLISLDLFKTRTFSIGIVGNIATRL
                     GTGCVPFLMPLMLQVGFGYQAFMAGCMMAPTALGSIIAKSMVTQVLRRLGYRHTLVGI
                     TVIIGLMIAQFSLQSPAMAIWMLILPLFILGMAMSTQFTAMNTITLADLTDDNASSGN
                     SVLAVTQQLSISLGVAVSAAVLRVYEGMEGTTTVEQFHYTFITMGIITVASAAMFMLL
                     KTTDGNNLIKRQRKSKPNRVPSESE"
     gene            complement(33804..34496)
                     /locus_tag="IT892_002357"
     CDS             complement(33804..34496)
                     /locus_tag="IT892_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAP3135569.1"
                     /translation="MPLSAQQLAAQKNLSYVLAEKLAQRILKGEYEPGTILPGEIELG
                     EQFGVSRTAVREAVKTLTAKGMVLPRPRIGTRVMPQSNWNFLDQELLTWWMTEENFHQ
                     VIDHFLVMRICLEPQACLLAATVGTAEQKAHLNTLMAEMAALKENFRRERWIEVDMAW
                     HEHIYEMSANPFLTSFASLFHSVYHTYFTSITSDTVIKLDLHQAIVDAIIQSDGDAAF
                     KACQALLRSPDK"
BASE COUNT         8345 a         8943 c         8831 g         8490 t
ORIGIN      
        1 ttattgggat ttgtctggtg aattatttgt cgctatcttt ccccgccagc agtttatcca
       61 gctcatcgcc accgacgtga cggaaatcct gccccttcac gtagtagaag ataaactcac
      121 aaatattctg gcagcggtcg ccaatacgtt cgatagaacg cgcgcagaac agcgcagtaa
      181 gtacgctcgg aatggtacgc gaatcttcca tcatgtaggt catcagttga cgaacaatac
      241 cttcgtattc ctgatcgact tttttatctt cacgataaat acgtaccgct tcgtcaatgt
      301 ccatccgcgc gaacgcgtcc agcacgtcgt gcagcatctg gatggtatga cggcccagcg
      361 actccagact taccagcaac ggctgatgct gctgggagaa tttctccagc gcagtacggc
      421 agattttgtc cgccacgtcg ccaatacgct ccagctcggc aatggtttta ctgatcacca
      481 taaccagtcg caggtcgctc gccgtcggct gacgtttggc gataatgcgc acgcaggctt
      541 catcgatcgc cacttccatc atgttgacgt tcttgtcgcc ttcgatgacg cgcttcgcca
      601 gatcgctgtc ctggttatgc atcgcggtga ttgcatcaga aagctgctgc tccaccatgc
      661 cgcccatggt catcacctgc gtgcggatac tttccagttc ggcgttgaac tggccggaaa
      721 tatgtttatt aagattgaga ctgtccataa cgcactcctg aatcaaccgt aacgaccggt
      781 gatgtagtct tctgtttgtt tcttcgctgg cttggtgaac agatcgtccg tgttgctgaa
      841 ctcaatcaat tcgcccaggt acataaacgc cgtgtggtcg gaacaacgcg cagcctgctg
      901 catgttgtgg gtgacgatca ccacggtgta atcctgcttc agttcggtga tcagctcttc
      961 aatacgcccg gtagagatag ggtcgagcgc cgaacacggt tcgtcgagca gcagcacttc
     1021 cgggcgaatg gcgataccac gcgcaataca cagacgctgt tgctgaccac cagagagaga
     1081 gtaaccgctc tggtgcaatt tatctttggt ttcgttccac aatgcggctt tggtcaatgc
     1141 ccactgcacg cgctcgtcca tgtcggcacg ggagagcttc tcaaacagac gaacgccaaa
     1201 agcgatgttg tcgtagatgg acatcggaaa cggcgtcggt ttctggaaca ccatgcccac
     1261 tttcgcacgc agcagtgcga tatcctgaga gttggtcagg atgttgtcgc catcaagcag
     1321 aatttcacct tccgcacgct gctccgggta cagttcaaac attttgttga aggtacgcag
     1381 cagcgtcgat ttaccgcagc cggacggccc gataaacgcc gttacctggt ttttagcgat
     1441 atccaggttg atgtttttca gggcatggaa tttgccgtag tagaagttca aattacgaac
     1501 ctgaatttta ctcggggcag tttcaaccat actcattgca atcttttcct catcgtgcct
     1561 gatgcacttc gctaatcagg cttaccgtag gccggatcag gcgttcacgc cgcatccggc
     1621 aaagtgttaa ccgtgtacag agtcaaaaag gcgctcggtc ggtcccctcg cccctctggg
     1681 gagagggtta gggtgagggg aaaaccgtgt cagcaatatc aaccgtgttt attcttcgca
     1741 aaaacaacgc gcgccagaat gttcagcagc agtacgcaca gggtaatgat caataccccg
     1801 gcccaggcca attgctgcca ttccgcaaac gggctcatcg caaacttaaa gatcgtcacc
     1861 ggcaggttgg cgatcggctg catcatgtcc gtgctccaga actggttgga gagcgcggta
     1921 aacagcagcg gcgcggtttc accagcaata cgggcaatcg ccagcaggat accggtcata
     1981 atcccggaca ccgacgcttt cagcgtaatc gcagagatca tcttccactt cggtgtaccc
     2041 agcgcataag ccgcttcacg caggctgtac ggcaccagtt tcagcatgtt ctcggtggtg
     2101 cggataacaa tcggcacctg caacaacgcc agggcaatca cgcccgccca gccggagaag
     2161 tgctccatct gcgccaccac aatggtgtaa acaaacagac caaccacaat cgacggcgca
     2221 gagagcagaa tgtcgttaat gaagcgaatc acttctgcca gccaggattt acgaccatat
     2281 tccgccagat aaatccccgc cataatgccc agcggcgtac cgaataccgt ggcccacaaa
     2341 attaacagcc cgctacccgc cagagcgttc gccagaccac caccttccgt attgggcggc
     2401 ggcgtcattt cagtgaacag cgccagcgac ataccgtcga taccgcgagt gatggtggac
     2461 attaaaatcc agatcagcca gaacaggccg aaggccatcg tcgccatcga gagcgtcagc
     2521 gcaatacggt ttttgaggcg gcgacgcgcc tgcattttgc ggcgagattc agccagcgcc
     2581 gcagtggttt gcatttcaac catagccatt agcgtgcccc ctcattctta gccaggcgca
     2641 taatcataaa cttcgatgcg gcgaggacga tgaaggtaat cacaaacagg atcaggccca
     2701 gttccatcag tgcggcaacg tgcagaccgg attccgcttc cgcaaattcg ttcgccagcg
     2761 cagaggtgat actgttgccc ggcatataca gcgaggcgct gtcgagctgg taggtgttac
     2821 cgatgataaa ggtcaccgcc atggtttcac cgagcgcgcg gcccagcccc agcatgatgc
     2881 cgccgataac accatttttg gtgaacggaa gaacgatacg ccagataact tcccaggtgg
     2941 tgcagccaat accgtaggcc gactctttca tcatcaccgg ggtttgttcg aacacatcac
     3001 gcattaccgc cgcaatgtac ggaataatca tgatggcgag gatcacgcct gccgcgagga
     3061 taccgatacc aaatgcgggg ccagagaaca gcgcgccaac aatcgggata ttcgacatga
     3121 tattgccgac cggctcctga aagtaaacgg cgaacagcgg cgcaaagata aacaggcccc
     3181 acatgccgta aacgatactt ggaatggctg ccagcagctc aatggcgata cccagcgggc
     3241 gtttcagcca gccaggcgca agctcagtca ggaacagggc gataccgaaa ctcaccggga
     3301 cggcgatcag cagcgcgata aacgaagtca ccaacgtacc gtagatcggc accagcgccc
     3361 cgtagatatc gttcggtgca tcccactctt tggtccatag gaaagccaga ccaaatttct
     3421 gaatgctcgg ccaggaggag atgatcagag agacaataat gccacccaac atcaatagca
     3481 caatcagcgc cgccagtttt accagcacgc tgaaaattat gtcgcccttt ttacccggtg
     3541 ggttaaaagc aggcttggtt gcagccataa gttactcttc agttaaacgc gtttacaaag
     3601 tcattttgta atgccggatg cggcgtaaaa caccgtaccc ggcctggagt tttattagta
     3661 cagcggctta ccgctactgt ctttaatatt ggtcttccac gcagcgcgaa cctgttcaac
     3721 tacactatcc ggcaggctgg cgtaatccag gtcgttcgcc tgtttagccc cggttttgta
     3781 cgcccagtcg aagaatttca gcacttctgt gccttgttct ggtttcttct gatctttgtg
     3841 gatcagaatg aacgtggtag aggtaatagg ccatgcatct tcgcctttct ggttggtcag
     3901 atcctgagcg aaggttttgc tccagtctgc accttttgct gcattagcga agttttcttc
     3961 ggtcggacta accggtttac catcagcgga gatcagtttg gtgtacgcca ggttgttctg
     4021 cttcgcgtaa gcatattcaa cataaccaat tgcccccggc agacgctgaa cgaacgcggc
     4081 gataccgtcg ttacctttac cgcccagacc gatcggccat tttacggtag agccagtacc
     4141 aacgttgttt ttccactctt cgttcacttt cgccaggtag ctggtgaaga cgaaggaagt
     4201 cccggagcca tctgcgcggc gtactacagc aatgttttgt gaaggcagtt tcagacccgg
     4261 attcagtttg gcgatggctt catcatccca cttcttgatt ttgcccaggt agatgtcgcc
     4321 gagggtttta ccatccagca ccagttcgcc agacttcagc cctggaatgt taaccgccag
     4381 caccacgccg ccaatcacgg tcgggaactg gaacagacct tcctgagcca gtttttcgtc
     4441 agacagcggc gcgtcagagg caccaaaatc aacggtatta gcgataatct gttttacgcc
     4501 accggaagaa ccgataccct ggtagttaac tttattaccg gtttctttct ggtaagtgtc
     4561 agcccatttg gcatacaccg gcgcagggaa ggttgcacct gcacctgtca ggcttgcttc
     4621 tgcaaacaca gagaaagcac tcatcgataa ggtcgcggcg acaacagttg cgacggtggt
     4681 acgcataact ttcataatgt ctcctgggag gattcataaa gcattgtttg ttggctacga
     4741 gaagcaaaat aggacaaaca ggtgacagtt atatgtaagg aatatgacag ttttatgaca
     4801 gagagataaa gtcttcagtc tgatttaaat aagcgttgat attcagtcaa ttacaaacat
     4861 taataacgaa gagatgacag aaaaattttc attctgtgac agagaaaaag tagccgaaga
     4921 tgacggtttg tcacatggag ttggcaggat gtttgattaa aaacataaca ggaagaaaaa
     4981 tgccccgctt acgcagggca tccatttatt actcaaccgt aaccgatttt gccaggttac
     5041 gcggctggtc aacgtcggtg cctttgatca gcgcgacatg gtaagccagc agctgcagcg
     5101 gaacggtgta gaagatcggt gcaatcacct cttccacatg cggcatctcg atgatgtgca
     5161 tgttatcgct acttacaaaa cccgcatcct gatcggcgaa gacatacaac tgaccgccac
     5221 gcgcgcgaac ttcttcaatg ttggatttca gtttttccag caattcgttg ttcggtgcaa
     5281 caacaataac cggcatatcg gcatcaatta gcgccagcgg accgtgtttc agttcgccag
     5341 cagcgtaggc ttcagcgtga atgtaagaga tctctttcaa cttcaatgcg ccttccagcg
     5401 cgattgggta ctgatcgcca cggcccagga acagcgcgtg atgtttgtca gagaaatctt
     5461 ctgccagcgc ttcaatgcgt ttgtcctgag acagcatctg ctcaatacgg ctcggcagcg
     5521 cctgcagacc atgcacgatg tcatgttcaa tggaggcatc cagacctttc aggcgagaca
     5581 gcttcgccac cagcatcaac agcacagtta actgagtggt gaatgcttta gtggatgcca
     5641 cgccgatttc tgtacccgcg ttggtcatta gcgccagatc ggattcgcgc accagagaag
     5701 aacccggaac gttacagatt gccagtgaac caaggtaacc cagctctttc gacagacgca
     5761 ggccagccag ggtatccgcg gtttcgccag actgtgacaa ggtgatcatc aggctgttac
     5821 gacgcacggc agatttgcga tagcggaatt cagaggcgat ttcgacgtcg cacggaatac
     5881 ctgctagcga ttcaaaccag tagcgggaaa ccataccgga gttataagaa gtaccacagg
     5941 cgaggatctg aatatgctca accttcgaca gcagttcgtc ggcgttcggt cccagctcgc
     6001 ttaaatcaac ctgaccgtgg ctgatgcgtc cggtaagggt gtttttgatc gcgttcggct
     6061 gttcgtagat ctctttctgc atgtagtgac ggtaaatgcc tttatcgccc gcgtcatatt
     6121 gcagattgga ttcgatatcc tgacgtttta cttccgcgcc agttttatcg aagatgttta
     6181 ccgaacggcg agtgatttcc gcaatatcgc cctcttcaag gaagataaag cgacgggtca
     6241 ccggcaacag cgccagctgg tcagaagcga taaagttttc gcccatcccc aggccaatca
     6301 ccagcggact accagaacgt gccgccagca gggtatccgg gtgacgggag tccatgatca
     6361 ctgtaccgta cgcaccacgc agctgcggga tagcacgcag aacggcctca cgcagagtcc
     6421 cgccttgttt cagctcccag ttcaccagat gggcaatcac ttcggtgtcg gtttcagaaa
     6481 cgaaggtata gccacgcgct tttagctctt cacgcagcgg ttcatggttt tcgatgatgc
     6541 cgttatgcac caccacaatg tgttcagaaa catgcggatg cgcattcact tctgaaggtt
     6601 caccgtgggt cgcccagcga gtgtgagcaa taccagtgcc gccatgcaga ggatgttctt
     6661 ccgctgcctg tgccagcatc tggactttac cgaggcgacg caggcgggtc atatgacctt
     6721 ctgcatcaac aacggccaga ccggcagagt catatccgcg gtattccaga cgacgtaaac
     6781 cttcaagaag gatttctgct acatcacgtt gcgcgatcgc gccaacaatt ccacacatag
     6841 tttttgattc cgatttatat cgttgtcggt caacctgtat gcccgttttt tcgggcgccc
     6901 cgagccttgt agagagtggg gttattttta tagttactgc ttgtgggagg gagattatgt
     6961 tatctcctca tcccatgtga ccgggttagc cggccagaat cactttttct ttaccggacg
     7021 acgccagcct tctttctgag tctgcggcac acggctgata gctaatgcat tttcgccgac
     7081 attacgcgtc acagttgtac ccgcagcaat ggtcgcgcct ttgcctactg ttaccggggc
     7141 caccagctga gtgtcggaac caacaaacac atcgtcgccg ataatggtct taaatttatt
     7201 cgcaccatcg tagttgcagg taatggttcc cgcgccgatg ttaacgttat cgccaatttc
     7261 cgcatcgccc aggtaagtca gatgaccagc tttcgagcct ttacccagac gcgctttttt
     7321 catctcaacg aagttaccga cgtgagcacc ttccagcaac tcagcaccag gacgcaaacg
     7381 ggcaaacggg ccaatggtac aggccgctgc cagattcgca tcttccacaa cggtatacgg
     7441 actgatttcg caatcatcgc caatcacgct gtttttaatc acgcaaccgg tgccaatttt
     7501 cacgcgatga ccgagagtca cgttgccctc gatgataacg ttagtatcaa tttcaacatc
     7561 gcgcccgtga gttagcgtac cacgcagatc aaaacgcgct ggatcgcgca gcataacgcc
     7621 tgctaacagc agtttttcag cctgttcgga ctgataaaca cgctccagac gggagagttg
     7681 caggcggtta ttcacgcctt ctacttcgct taaacgttgc ggatgaacgg cgacgatttc
     7741 acgcccttcc tgatacgcca gcgcaataat gtcggtgatg tagtattcgc cctgagcatt
     7801 attgttggtc agcttcgcca gccagcgttt catatctgcg ccgttggcaa tcagaatgcc
     7861 ggtgttgatc tcctgaatct gacgctgctc gtcggtggca tctttgtgct caacaatgcc
     7921 ggtaactttg ccgttttcac gggtgatacg tccataaccg gtcggatcat ccagtttcac
     7981 cgtcagcaga ccaatgccac cctgcggttt agcatcacgc agacgctgga gtgtttcgac
     8041 agagatcagc ggcacgtcgc cgtagagcat taaaatgtct tcatcatcgg caaagaaagg
     8101 tgcggcctgc tgcattgcat gacccgtacc cagctgctct gcctgaagca cccagttaag
     8161 gttgtcgtct ttcagcgcct gttttagcag atcgccgccg tgaccgtaca ccaggtgaac
     8221 gtgcgctgcg cctaattcat tcgcagcatc aatgacatgc tgaaccatcg ctttcccggc
     8281 aagggtatgc agcactttcg gaagatcgga atacatgcgc gtgcctttgc ctgcggcaag
     8341 gatcactacg ctcatagcat tattcaacat acgcgtcctg actgtaattt gagaacgaat
     8401 ttaaaccgct tcaccttgaa aaaactacat ttttttcatc gtgaaatgga cagaggataa
     8461 attgttcaat aacggattat ccccgctgac gaaagcgcca ttttcgacca tcgtcacgcc
     8521 ttttgtctgc agaaaattaa ggcagtacct taatttaagc gtcaggtgga tgtttttgct
     8581 cttatttcga tcaatgaata aacaggaaaa cagggggttt tatatcagca ggatctatgt
     8641 gaacgctatt caggacgggt cacacgcgca aaaaaaagcc agcctgtttc cagactggct
     8701 tttgtgcttt tcaagccggt gttacatcgc ttttttggtc aactcgataa cgcgcagctg
     8761 cgcgatcgct ttggccagtt ccgcagacgc ctgagcgtaa tctacgtcgc cgtgagagct
     8821 gctaatgtgc tcttcagcct tacgtttcgc ttccatggct cgcgcttcgt cgagatcctg
     8881 gccgcgaatt gcggtgtcgg ccagaacggt cacgttgcca ggctgcactt caagaatgcc
     8941 gccagacaga tagataaact cttcgtgacc gtgctgtttc acgatgcgaa tcataccagg
     9001 cttaatggcg gtgagcagcg gtgcgtggcc agggtagatc cccagttcac cttcgctacc
     9061 cgttacctgg attttctcga ccagaccaga gaacatttgt tgctctgcgc tgacgacgtc
     9121 caggtggtaa gtcattgcca tatcaccctc cgattaaggc gttaaagttt tttggctttt
     9181 tccacagctt cttcgatgga accgaccatg tagaacgcct gctccggcag gtgatcgtat
     9241 tcgccttcca tgatgccttt aaagccacgg atggtgtctt tcagggagac gtatttaccc
     9301 ggagaaccgg tgaatacttc tgccacgaag aacggctggg acaggaagcg ctggatctta
     9361 cgagcacgcg ctaccaccag tttgtcttct tcagacagtt catccatacc caggatggcg
     9421 atgatgtctt tcagttcctg ataacgttgc aggatggact gaacgccacg cgcggtgtcg
     9481 tagtgttcct gaccaaccac cagcgggtcc agctgacggc tggtggagtc cagcgggtca
     9541 acggccgggt agatacccag agacgcgatc tgacggctca gtaccacggt tgcgtcaagg
     9601 tgcgcaaagg tggttgccgg agacgggtca gtcaagtcat ccgcaggtac gtatactgcc
     9661 tgtacggagg tgatagaacc agttttggtg gaggtgatac gttcctgcag aacgcccatc
     9721 tcttccgcca gggtcggctg ataacctacc gctgaaggca tacggcccag cagtgcggat
     9781 acttccgtac cggccagggt gtaacgatag atgttgtcaa cgaacagcag aacgtcacga
     9841 ccttcgtcac ggaatttctc agccatggtc agaccggtca gagcaacgcg cagacggttt
     9901 cccggcggct cgttcatctg gccatacacc agggatactt tgtcgataac gttggagtcg
     9961 gtcatttcgt ggtagaagtc gttaccctca cgagtacgtt cacctacgcc cgcaaacaca
    10021 gagtaaccgg agtgctcgat cgcgatgtta cgaatgagct ccatcatgtt tacggtttta
    10081 cctacacccg caccaccgaa cagaccaact ttaccgccct tagcgaacgg acacatcagg
    10141 tcgataactt tgataccggt ttccagcagt tcctgagagt ttgacagctc ttcgtaggaa
    10201 ggtgctgcgc ggtgaatcgc ccaacgctct tcttcaccga tctcgccttt catgtcgacc
    10261 ggttcaccca gtacgttcat gatacggccc agagtcgctt tacctaccgg gacttcaatc
    10321 gggtgttcga ggtcttttac atccagaccg cgacgcagac cgtcggagga acccattgcg
    10381 atggtacgta cgataccgcc gccgagctgc tgctgaactt ccagcaccag acgctcatta
    10441 ccattttgca cctcaagagc atcgtacacg cgcggtacgg catcctgagg gaattcgacg
    10501 tcaactacgg cgccgattac ctggacaatc tttccagtag ccatcttaaa tcctctacga
    10561 aataacctgt ttaaaccgcg gcggcccccg agacgatctc ggtgagttcc tgagtaatgc
    10621 tggcctgacg agctttgttg tataccaact gcagctcttt aatcaggctg ccgccattgt
    10681 cggtcgcggc tttcatcgcc accatacggg cggcctgctc gctggccagg ttttcaacca
    10741 cgccctgata aacctgagat tcgacataac gacgcagcag ggtatccagc aacgccttcg
    10801 gatcgggttc gtacaggtaa tcccaggatt tatgtttcag atcatcatca tctgatgccg
    10861 gtaacggcag cagctggctg atggtcggaa cctgagacat ggtgttaata aatttgttgc
    10921 tgacaatgta aagcttgtcc agacggcctt cgtcgtaggc ctgcaacatc acttttaccg
    10981 gaccgatcag ttcggacagg gaagggttat cccccatgcc ggtgacctgg gcaacaacat
    11041 tgccgcccac ggagttgaag aacgacacgc ctttcgagcc gatcattgcg aggtcgcatt
    11101 gaacgccttt gtcggtccag gtcttcattt ccgccagcag ttttttgaac aggttaatgt
    11161 tcaaaccacc gcacaaacca cggtcggtcg acaccaccag gtagcccacg cgtttaacgt
    11221 cgcggtcttc caggtaaggg tgcttatatt ccagattacc gtgtgcaagg tgaccaatca
    11281 ctttgcgcat ggtttctgca taaggacggc tggccgccat gcgatcctgc gatttacgca
    11341 ttttggaagc ggcgaccatc tccatcgctt tagtgatctt ttgcgtgttc tggacgcttg
    11401 cgatcttact acgtatctct tttgcgccgg ccatgagctt ctcctcaatg ccttgcggcc
    11461 tgccctaagg caagccgcca gacgttacca ggattgggtt gctttgaagg aatcgaggat
    11521 gcctttcagc ttgccttcga tttcgtcgtt gtagccaccg gtctggttga tctcttgcat
    11581 caacggagcg tgatcacggt cgacgtaagc cagcagagcg gcttcgaagc tgccaatttt
    11641 cgacagttca acatccgcca ggtaaccacg ttctgctgcg aacagaacca gagactgctg
    11701 cgcaacggac atcggcgcat actgtttctg tttcagcagt tcggtcactt tctgaccgtg
    11761 gtcaagctgc ttacgtgttg catcgtcaag gtcggatgca aactgagaga acgctgccag
    11821 ttcacgatac tgtgccagag cggtacggat accaccggac agttttttca tgatcttggt
    11881 ctgtgctgca ccaccaacac gggatacgga aatacccggg ttaaccgcag gacgaatacc
    11941 ggcgttgaac aggttggttt ccaggaagat ctgaccatcg gtaatggaga ttacgttggt
    12001 cggaacgaac gcagaaacgt cacccgcctg agtttcgata atcggcagtg cggtcagaga
    12061 accggttttc cctttcactt cacctttggt gaaggcttca acgtattcgg cgttaacacg
    12121 tgcagcacgc tccagcagac gagagtggag gtagaaaacg tcgcccggga atgcttcacg
    12181 tcctggcgga cgacggagca gcagggagat ctgacggtaa gcaacagcct gtttagacag
    12241 gtcatcgtaa atgatcagcg catcttcacc gcggtcacgg aagtattcgc ccattgcgca
    12301 accggcatac ggtgccaggt attgcagtgc agcggattca gacgcggttg ctaccacaac
    12361 gatggtgtta gccagtgcgc cgtgctcttc cagtttacgt accacgttag aaatggtgga
    12421 cgctttctgg ccgatagcga catagataca tttgataccg gaatcgcgct ggttgatgat
    12481 ggcatcgata gccagtgcgg ttttacctgt ctgacggtca ccgatgatca attcacgctg
    12541 accacgaccg attgggatca tggagtcaac ggctttataa ccggtctgta ccggctgatc
    12601 tacggactga cgttcgataa cgcccggagc gattgcttct acagcagaga agccgtcgtg
    12661 atccagcgga cctttaccgt cgattggtgc acccagagtg ttaaccacac ggcccagcag
    12721 gccacggcca accggaactt ccaggatacg gccagtacac ttaactttca tgccttcggc
    12781 aaggtcagcg tacggaccca taacaaccgc acctacagag tcgcgctcga ggttcagtgc
    12841 gatagcgtaa cggttacccg gcagggagat catttcaccc tgcatacaat cggccaggcc
    12901 gtgaatgcgg ataacaccgt cacttacaga aacaatagta ccttcgttgt gagcttcact
    12961 cacaacattg aactgagcaa tgcgctgctt gatcagttcg ctgatttcgg tggaattcag
    13021 ttgcatgctc cagtcccctt aagactgcaa gacgtctgca aggcgctcaa gacgaccgcg
    13081 tacgctgcca tcaatgacca tatcacccgc tcggatgata acgcctgcca ttacagactt
    13141 atcgattttg caattcagct taactttgcg tgacagacgt ttttccatcg cagcagaaat
    13201 tttcgcgagc tgttgttcac tcagtgcggc agcggaaatg acgtctacct cagcggtagc
    13261 ctcactcacg gcacgcaggt gaataaactg ctccagaaca tccgggagcg cgttaagacg
    13321 accattttca gccataaccc gaatcaggtt ctgaccgttt tcgtccagtt gctcaccaca
    13381 aactgcgata aacgactcgg cgagcgtttc tggcgcaagc gcgccagaga gaagctctgc
    13441 catttgttcg tttttggtta cctcggcggc aaacgccagc atgtcctgcc agcgttctac
    13501 actttggtgt tcgacggcaa agtcaaaagc tgctttggcg taggggcgag ctaccgtaat
    13561 aaattcagac atcagcccct ccctccttac agttcagcga caagtttatc cacgatgtcg
    13621 ctgttagcag cttcatccac ggaacgttcg atgatcttct cggcgccagc aacagccagg
    13681 atagcaactt gcttacgcag ctcttcacgg gcacgtttac gctcggcttc aatttccgcc
    13741 tgcgcctggg ccacgatttt agtacgttcc tgttctgcct cagctttcgc ttcgtccaga
    13801 atctgcgagc ggcgtttgtt cgcctgctcg atgattacct gggcttccgc tttcgctttt
    13861 ttcagctggt cggtcgcgct ggcctttgca aggtcaaggt ccttatgtgc tcgttctgcg
    13921 gaagcaaggc cgtcagcaat ttctttttga cgtttttcga tggctgccat taatggcggc
    13981 catacgtact tcatgcagaa cagaacgaac aggacaaacg cgatggcctg gccgaggatt
    14041 gttgcgttaa gattcacagc acaatgcctc tatttagtta acgttctgat attgctcttt
    14101 aaataaaagc aacgcttact acgcgacagc gaacatcacg tacagaccca gacctacagc
    14161 gatcatcggg atagcatcca ccagacccat aacgataaag aactgagtac gcagcagagg
    14221 aatcagatca ggttgacgcg ctgcgccttc caggaattta cccccgagga tgccgatacc
    14281 gatcgcagca ccgattgccg ccagacccat catcacagcg gcagccatgt acagcagatc
    14341 catattcagg ttttccatga cagtctccag tttgtttcag ttaaaacgta gtagtgttgg
    14401 taaattaatg ttcttcagac gccatcgaca gatagacgat cgtcagaacc atgaagatga
    14461 aggcttgcag cgtaatgatc aggatgtgga aaatggccca cggcacattc aggatccact
    14521 gtgaccacca cggcaacaga ccagcaatca gaatgaaaat cagctcaccg gcatacatgt
    14581 taccgaacag tcgcaaaccg agtgaaactg gtttggacag caggcttacc ccttcaagga
    14641 ttaagttgac aggaatgaac gcccagtgat tgaacggctg cagcgtcaac tctttcgtga
    14701 agccgccgat gcctttcatt ttgatgctgt agaacagaat caggataaat acgcccagtg
    14761 ccatagacag cgttacgttc acgtccgcag acggaaccac acgcagtgca ggcagaccca
    14821 gtacatgttc agcaatgtac ggcagcaggt cgataggcag taaatccatc aggttcatca
    14881 ggaataccca gacgaagatc gtcagggcca gcggagcaat cagcttgctt ttgccatggt
    14941 acatgtcttt cacgctacca ttaacaaagc cgatcaccag ctcaatcgcg gtctgaaact
    15001 tacctggcac accgctggtc gcctttttgg ctacgctacg gaataaaacc aggaacaaca
    15061 gacccagcac caccgagaag aacatggagt caatattgat tgtccagaag gtggctgggg
    15121 ggttttgtgg atccaccagc gagaatgtac gcaggtccag ctgaaggtta ttcaggtggt
    15181 gtcctatgta atcctgcggc gtcatatttt ctgaagccat gatgcctttt accctttgtt
    15241 gttaattaca gccggtgcca gtatctgaac caccagcacc aaaacccacg taacgatcag
    15301 cggcaagaat accgccttta aaaccgccaa cgccaccacc agtaacacca acatcgccag
    15361 aactttgaaa gcttcgccaa atgcgaatgt ccaggccacc cggcctttcg ctggtgtatg
    15421 cgcctggtga cgccaggcaa atatcataaa caaaacgtta ggcagaaaga ctgccaggcc
    15481 cccgcttatt gcagagacgc cccagaaggg gtctttgagg ctgaacagca atccacttgc
    15541 tatcaccacc agtaactgaa cgagcagaag cttccgagca acgtttcgac tcacgagcga
    15601 cacagacatc acgtttttca ctcctgctcc cttcgaggta tgccgcgtgt cgtataaaac
    15661 tttctttaag gcttagagtc aagcatcaaa aagcggtcaa attatacggt gcgcccccgt
    15721 gatttcaaac aataagtagc caaaaggtga ataaatgttt aaatattttt ccagtgcata
    15781 caattgcgac ttttctgcta accctgttcg atcatgaaaa actgtaaata acgcgtaaac
    15841 actggtgata aagcgtgctt cagatcacat attgcgcatg ttcgcgcaca gcatatttat
    15901 ttacttggca aatgatgcct ttgcaagttt atgatatttc agtctaaaaa cagatactgt
    15961 tttaataaat gacatttaca caacaaaaac cacccattga catttttaat aatgttttaa
    16021 cagccaatga tggttcttag cgccgatttt tagcagactg atattttcac taatgactta
    16081 ttttctgctt accaaaaaaa gccacgttat cttgttgatg caaaagagtg aacgtggcgt
    16141 taaatgtaac cagttatatc agtagaaaac ctggttgttg ttaacagtct aaccggtcaa
    16201 ttttttatga tttttttgat aaaaattaaa ttttatttgc tttaatcacc accagatgac
    16261 gttcgccatc cagggctgga acctgaagtt taaccactga ttcgacctga tattcttcgg
    16321 gcaacaaagc gatttcatct tccggcattt gccctttcag cgcgtagaaa cggccttgct
    16381 caccaggaag atggtggcac cagctcacca tatcgttcag agaggcaaaa gcgcggctaa
    16441 ttacgccatc aaatggcggc tctgaaggaa actcttctac cctgctctgt actggttcaa
    16501 tattctccag tttaagctca tgttgcacct gacgaaggaa acgcacgcgt ttaccaaggc
    16561 tatccaacag agtgaaatgg gcttcaggac gcacgataga gagtggaatg cctggcagtc
    16621 ctggtccggt gccgacatcg ataaaccgtt caccttgcag atacggtgcc accacaatgc
    16681 tatcgagaat atggcgtacc agcatctcat taggatcgcg gaccgaagtc aggttgtacg
    16741 ctttgttcca tttatgcagc atattcacgt aggcaataag ctggtttttc tggtgatcgg
    16801 taagcgaaat acctgcgtct ttcagcagta aggagagttt gttgagcacg gtgattacct
    16861 gttcttgatg cgttgcctgg taagcgggtg cttaccaggc atttttaatg cgttatgcgc
    16921 tacgacgcag cataccctgt tttttcagcc acaccagcag aatggagatg gccgcaggcg
    16981 tgacgccaga aatacgcgaa gcttggccga tagaggctgg tttgtgatcg ttaagtttgg
    17041 cgatcacttc gttagaaaga ccggatacct ggcggtaatc cagtgtcgcg ggtagcaggg
    17101 tgttctcgtt acgcagctgc ttttcgatct catcttgctg gcgcgcgata taaccttcgt
    17161 atttaacctg aatctcaacc tgttccgccg cctgttcgtc tgtcaacgaa ggggcaaacg
    17221 gcgtcagcgt ggttaatttt tcataagtca tttccggacg acgcagcaga tcttcaccac
    17281 tggcttcacg ggaaagcggc gcagtcaggt gagcattcac ttcggctgca gcttccgccg
    17341 acggggttac ccaggtcgat ttcagacgct gacgctcacg ctcgatattc tcaagtttct
    17401 cgttaaagcg cgcccaacgt tcgtcatcca ccaggcccag ttcacgaccg atttcagtca
    17461 aacgcagatc cgcattatct tcgcgtagca tcagacgata ttctgcgcgc gaagtaaaca
    17521 tacgatacgg ttctttggtt cctaaagtgc acaggtcatc aactagtacg ccgagatacg
    17581 cctgagaacg tgccggagcc caaccttctt tgtcagcaga cagacgggca gcgttaagac
    17641 cggccagcaa accttgcgca gcggcttctt cgtaaccggt agtgccgtta atctgaccag
    17701 caaagaacag cccctggata aacttgctct ccagcgtcgg tttcaggtcg cgaggatcga
    17761 agaagtcata ctcaatggca taacccggac gcacgatctt cgcgttttcc atcccctgca
    17821 tagagcggac gatttgcatc tgcacatcga acggcaggct ggtggagata ccgttcggat
    17881 aaatttcatt agaggtcagt ccttccggtt caaggaagat ctgatgctga tttctgtcgg
    17941 cgaagcgcat gactttgtct tcgatcgacg ggcagtagcg tgggccgaca ccttcgatca
    18001 cccctgcgta cattgggcta cgatcgaggt tactgcggat cacatcatgg gttttctcgt
    18061 tggtatgagt gatataacac ggcacctgct ggggatgctg ggacgcattg cccataaacg
    18121 agaataccgg cattgggtta tcgccatgct gttgcgccag tacgctaaag tcgatggttc
    18181 gagcatcaat acgcggtggt gtcccggttt tcagacgacc aacgcgcagc ggcagttcac
    18241 gcaaacggcg agaaagcgga atggacggcg gatcaccagc acggccaccg ctgtaattat
    18301 ccagaccgat atgaatttta ccgtcgagga acgtcccaac ggtgagcacg acggctttgg
    18361 cacggaactt cagtcccatt tgggtaacag caccgaccac gcgatcgttt tcgacaataa
    18421 gatcttcaac cgcctgctgg aagatcatca ggttcggttg gttctccagc gccgtacgta
    18481 ccgcctgacg gtagagcaca cgatccgcct gagctcgggt agcgcgaacc gccggtcctt
    18541 tgcttgcgtt tagtatccta aactggatac ccgcctgatc gatcgctttc gccatcagac
    18601 cgccgagtgc atccacttct tttaccagat gtcccttccc aataccgccg atcgccgggt
    18661 tgcagctcat ctgccccaga gtgtcgatat tgtgtgtcaa aagcagagtc tgttgaccca
    18721 tacgcgccgc ggccatcgcg gcctcggtgc ctgcatgacc cccgccaatg atgatgacgt
    18781 caaaaggatc cggataaaac atggtgattg cctcgcataa cgcggtatga aaatggattg
    18841 aagcccgggc cgtggattct actcaacttt gtcggcttga gaaagacctg ggatcctggg
    18901 tattaaaaag aagatctatt tatttagaga tctgttctat tgtgatctct tattaggatc
    18961 gcactgccct gtggataaca aggatccggc ttttaagatc aacaacctgg aaaggatcat
    19021 taactgtgaa tgatcggtga tcctggaccg tataagctgg gatcagaatg aggggttata
    19081 cacaactcaa aaactgaaca acagttgttc tttggataac taccggttga tccaagcttc
    19141 ctgacagagt tatccacagt agatcgcacg atctgtatac ttatttgagt aaattaaccc
    19201 acgatcccag ccattcttct gccggatctt ccggaatgtc gtgatcaaga atgttgatct
    19261 tcagtgtttc gcctgtctgt tttgcaccgg aatttttgag ttctgcctcg agtttatcga
    19321 tagccccaca aaaggtgtca tattcacgac tgccaatacc gattgcgcca aagcggactg
    19381 cagaaagatc gggcttctgt tcctgcaatg cttcatagaa aggagaaagg ttgtccggaa
    19441 tatctccggc accgtgggtg gagctgataa ccagccagat ccctgaggca ggtaaatctt
    19501 ctaacagcgg accgtgcagc gtttcggtgg taaaacccgc ctcttccagc ttttcagcca
    19561 ggtgttctgc tacatattcg gcaccgccga gggtgctgcc gctgataaga gtgatatctg
    19621 ccataaaccg ccacctttat taagagtggc gtattgtacg ctgtgaacgc gttgggatct
    19681 acctgtggaa aagtatggga ttaaaaaagc cgatcagggc ttgatggtac gcatgatcgg
    19741 gttttgcagg acgatcaatg tctcggtgga ctgaatttca tcaattgttt ggatcttgtt
    19801 gataagtaca tgctggagag cgtcgatcga acggcacatc acttttataa agatgctgta
    19861 gtggccggtt gtgtaatagg cttcagtgac ttcatcaagg ctttccagct ttgccagcgc
    19921 ggaagggtag tctttggcgc tctttaatat aatgccgata aagcagccta cgtcataacc
    19981 gagctgcttc gggctgacat caatacgcgc cccggtaatg atccccgcct gcttcatttt
    20041 ctctactcga acgtgaatcg tccccggact gacgccaaat tgtttcgcca gttcggcgta
    20101 agcggtgcgc gcattgccca ttaatgcttc caggatgcca cggtccagat tgtcgatcag
    20161 ataattttcc ataggatttt cttatgcgga ttgatgattc attctatttt agccttcttt
    20221 tttaatgaat caaaagtgag ttaggctttt tattgaatga ttattgcatg tgtgtcggtt
    20281 tttgttgctt aatcataagc aacaggacgc aggagtataa aaaatgaaaa ccgcttacat
    20341 tgccaaacaa cgtcaaatta gcttcgtgaa atctcacttt tctcgtcaac tggaagaacg
    20401 tctggggctg atcgaagtcc aggcgccgat tcttagccgt gtgggggatg gcacgcagga
    20461 taacttgtcg ggctgtgaaa aagcggtgca ggtaaaagtg aaagctctgc ctgatgccca
    20521 gttcgaagtg gttcattcac tggcgaagtg gaaacgtcag accttagggc aacacgactt
    20581 cagcgcgggc gaagggctgt acacgcacat gaaagccctt cgccccgatg aagaccgtct
    20641 ttctccgttg cactcggtct atgttgatca gtgggactgg gaacgcgtaa tgggcgacgg
    20701 tgagcgtcaa ttctcgactc tgaaaagcac ggtagaggcg atctgggcgg gaattaaagc
    20761 aaccgaagct gcggttagcg aagagtttgg cctggcaccg ttcctgccgg atcagatcca
    20821 cttcgtacac agccaggagt tactgtctcg ttatccggat cttgatgcca aagggcgtga
    20881 gcgggcgata gcgaaagatc ttggcgcggt attccttgtc gggattggcg gcaagctgag
    20941 cgatggtcat cgccacgacg tgcgcgcacc ggattatgat gactggagca ccccgtcaga
    21001 gctgggccat gcgggtctga acggcgatat tctggtgtgg aacccggtac tggaagatgc
    21061 gtttgagctt tcctccatgg ggatccgtgt agatgccgac acgctgaagc atcaactggc
    21121 gctgaccggt gacgaagatc gcctggagct ggagtggcat caggcgctgc tgcgcggtga
    21181 aatgccgcag accatcggcg gcggtatcgg ccagtctcgt ttgactatgc tgctgctgca
    21241 actgccgcat atcggccagg ttcagtgtgg agtatggcca gctgctgttc gcgagagcgt
    21301 cccttctctg ctgtaataat ttatcgccgc cagcgtctga gcaggcggct tcgcatcccg
    21361 gtatcaaagc gccagatatg atcgaaaatg cgcatgatgc cgggtttgcc gtgtgccgac
    21421 atcgccacgg catgaaagcg atgctgatgt acccgctgca gctctttcac tttactcgtc
    21481 acgtcgtcag gcaaccgctg agcgataaaa tcagaaatca ccaccgcatc ggcatcaaac
    21541 cattccctgc tttgcaagcg ttccataatg gcgcgaaaac aactggcaag atcggtgccg
    21601 ccacgaaact gctggcttaa aaaacggatt gcttgttcga tgccttgtgg gcctgaaagc
    21661 tcataacgga cgatctcggt ggaaaatagc ataatatagc agcgccggtt ttctgcgaga
    21721 gcaatgcgca tcaaggccag gcagaacgct ttcgcacact gttcattaaa gccgcccatt
    21781 gagccggaag tatccacaca gacaataaac ggcccgcgcg gctgttcatc gtaatcttta
    21841 tgtaccaccg gacgttcgat cactttttca cgccacgact caccgtgcag gcgataggtg
    21901 agcaactgtt tttccaccag ccgacggtaa aactcatact ccagttccgt tatccctagt
    21961 gtcgccagtt ctggcggcag gagacgtaaa atatcatcgc tttgttgcag accatcaacc
    22021 tgctcaggaa ccgtcgccgg ttcgcgcacc atggtgcgga aggtttccat ctgcgcatcg
    22081 ttgcgcggta ttgatttggc ttcccgagaa cgccccagct gctctgccag gcgtttcagt
    22141 tccggctgtt cgttaagaaa ttcaccgtat ttcacaatca actgatagtc gccacgttta
    22201 agctgaccgg cgctcatatc ccacagacga ccagctgcag tattgttatc tgcgagaatc
    22261 ggttcaagtt gtccgctcag cgtcatgcgt tcctgaactt cactcaacag ttgttcgcgt
    22321 tcttcttcta atagctgttg atttaacgtc gttgcttgca cgatcagact taaacgccaa
    22381 cgctggagaa aaagcgtgtg taacgctgaa gtgatcgtgc tgttagcatc aaccaactgt
    22441 cgggcttgtt ctgcccatgg agaattcaga cgatgcagta agtccaggat ctgtggtagc
    22501 tgcacaataa actgtggcgt ggagaggagc tggctttgct gatagcacat cacctcttcg
    22561 gtgagttccg gcgggactcg ggcatctttc agccgactgc gcagcgcttc acgccagcgg
    22621 ggaacatcat cagtgattgc cgccttcagg cgtgggaatt tttcaaagaa gaccgccagc
    22681 tgcggtgagg ccagcagtgc gatgatcatc tcttcgatca atccctcttc gctgacggcc
    22741 agcatcacat taagcgtatc cagcgttagc attgttgtgc ctggcgaatc tgtgcaccga
    22801 catcctgtag gctggcttca atgcgaccta accagtcgcc agggataaac agacattttt
    22861 gctgttcgct gaataaagcg tgttgcttgc gccagtcgct ttcaagctct tccagttgtt
    22921 gttttatttc accaggcaga ccttcagccg atgaaccggg aagtgccagc gtactgcctt
    22981 gtaaacttac atcgcgaacg acaagatgtt gggcgctatc aacttccaga ttcagtttct
    23041 gggcaaagcc gataccgttc agtttaccgc gaatttcacc acctttgctc agccactgtt
    23101 ccagcgcgct acgctcaaag gagatatgaa ccacttccat atcatgcagt tttaacggtt
    23161 tttgcagcag tagagtcaga gtggaagcag taacgttaac aggaagttga tactgctgac
    23221 gacggctgaa aatgccgccc agacgaatta ccgttaaggc tgttttatcg ctttgttgct
    23281 gctggagttg caggtgacgt tgcacaatcg cgccaaggcg agtcaacatc ccttgctgtt
    23341 gccaggcgtg accggtcatc aatacatcaa tttgttgttg tatcaaattc aggctttgcg
    23401 cgtcatacca caggcaatct ttcagcaaaa tgagatctac cggggtaaca gcactgcgac
    23461 cgctaaaaaa ggcgctggcc tgcaataatc ggatcgcttt tttccagcga cgatccgaga
    23521 cataaggcgc atccggtaat ttatccagtt gctggcgcag cataaaaatc agctcaaata
    23581 catgatcggg cagcgtaatt tcaccaatct ctttctgcca gcgttcatat tcttcatctg
    23641 tgacctgcaa ggcatcagga accggattgt cgttttcatc ctgttgactg gtcagcatgg
    23701 agcggaaatt cgctttatcc tgcactttat ctaaccacag acgaatcagc atgcggtcat
    23761 ataacgcttc cagactgctg tctgcttccg gcagctcgtt ggaggccgcc accagcagac
    23821 gcattgggat tttttctacg tgtgcaccgt tgcggaactg gcgctcgtta atggcggtga
    23881 gcaaggtatt aagaattgcc gggcccgctt tccagatctc atccagaaag acaatttctg
    23941 cttccggcag gtaaccgctg gttaaacgtt catagcgccc ttcatctttt agcgcctgaa
    24001 tagaaagggg accaaaaact tcttccggcg tggagaagcg ggtcatcaga tattcaaacg
    24061 cgcgggcatt ctgaaaggcg aattttaagc gccgggcgat caaacttttg gcaatacctg
    24121 gcgggccaag gaggaacaca ctttcaccac ttaatgccgc taataaacac aagcggatgg
    24181 cgtggctacg ttcataaagc cccttttcca acgaactgct caggcgggaa attctttccg
    24241 ctaataaatg agggtgagcc ataatgaagt ggcgtccttt cgtcaaaagt tctgcgtaaa
    24301 ttgcgagtat agacgtttct tgctggtggc taaaatagtc tcaaaggggg ggtatttttc
    24361 tttgagccag gttaatgtgg ccgcatttag gagtacgatt ttgccgttaa tcgtgcatac
    24421 tgtgcgcttt tttgtgggcc aagggactaa gcacacattt catatttcaa cgaaagacta
    24481 gtctatgagc actgataata agcaatcatt gcccgcgatt accctcgcgg cgattggagt
    24541 tgtctacggc gatattggta ccagcccgtt atatacactt cgtgaatgtt tgtccggcca
    24601 gtttggtttt ggcgttgaac gcgatgccgt gtttggcttt ttatcgctga tcttctggct
    24661 gctaatcttt gtggtttcca ttaaatatct caccttcgtg atgcgggcag ataacgccgg
    24721 tgaggggggg atcctgacgt tgatgtcgct tgccgggcgt aatacgtcgg cgcgaaccac
    24781 atcaatgctg gtgattatgg ggctaatcgg cggcagcttt ttctatggtg aagtcgtcat
    24841 aacacccgct atttcggtga tgtcagccat tgaaggtctg gaaatcgtcg ccccgcagct
    24901 ggatacctgg atagtttccc tctcaattat cgttctcact ttattattta tgattcaaaa
    24961 acatggcacg gctatggtcg gtaagctgtt tgcgccgatc atgctgacct ggtttttgat
    25021 tctggcagga ctggggttac gtagcattat tgctaacccg gaagtgctgc atgcgctgaa
    25081 tccaatgtgg gcggtgcatt tcttccttga atacaaaacg gtttctttta ttgcattagg
    25141 ggcagtggtg ttgtcgatta cgggggtcga ggcgctgtat gctgatatgg ggcactttgg
    25201 taagttccct attcgcctgg cgtggttcac cgtcgtatta ccttccttga cccttaatta
    25261 cttcggtcag ggagcgctgt tgttaaagaa cccggaagcg attaagaacc cgttcttcct
    25321 gttggcaccg gactgggcgc tgatcccgct gctgatcatc gccgcactgg cgacggtaat
    25381 tgcctcgcag gcggttatct ctggcgtctt ctcattgacg cgtcaggcgg tacgtctggg
    25441 atatttgtcg ccgatgcgca ttattcacac ctccgaaatg gagtcagggc aaatctatat
    25501 tccgtttgtg aactggatgc tctatgtcgc ggtcgtgatt gtgattgtca gctttgagca
    25561 ctccagcaac ctggcggcgg cgtacgggat tgcggtgacc ggaaccatgg tgctgacgtc
    25621 tattctctcg actaccgtgg cacgtcagaa ctggcactgg aataagtatt ttgttgcgct
    25681 gatcctgatt gctttccttt gtgtcgatat tccattgttc accgctaacc tcgataaact
    25741 gctctccggc ggctggttgc cattgagcct cggtactgtg atgtttatcg tgatgaccac
    25801 ctggaagagc gagcgtttcc gcttgctgcg gcggatgcat gaacatggta actctctgga
    25861 agcgatgatt gcttcgctgg agaaatcacc gcctgctcgc gtgcccggga ccgcggtgta
    25921 tatgtcgcgt gcaatcaacg tcattccctt tgcgctgatg cataacctta aacataacaa
    25981 ggtattgcat gagcgggtga ttctgttaac tctgcgcacc gaagacgctc catatgtcca
    26041 taacgtccgt cgggtacaga ttgaacaact gtcgcccact ttctggcgcg tggtggcaag
    26101 ttatggttgg cgagaaacgc caaacgtaga agaagttttc caccgctgcg gtctggaagg
    26161 attaagttgc cggatgatgg aaacctcctt ctttatgtcg catgagtcgt tgatcctcgg
    26221 caaacgcccg tggtatttgc gtctgcgcgg caagctgtac ttgctgctgc aacgtaatgc
    26281 gctgcgtgca ccagatcaat ttgaaatccc gccaaacagg gttatcgaac tgggtactca
    26341 ggtcgaaatc taacgccaga cgcctccttt cttcataagg gggcgttttt gttttcatgg
    26401 ttaatcacca tgtaaaacgt ttcgaggttg atcacatttc cgtaacgtca cgatggtttt
    26461 cccaactcag tcaggattaa actgtgggtc agcgaaacgt ttcgctgatg gagaaaaaaa
    26521 tgaaaaaagg caccgttctt aattctgata tttcatcggt gatctcccgt ctgggacata
    26581 ccgatacgct ggtggtgtgt gatgctggtt tacccatccc caaaagtaca acgcgtatcg
    26641 atatggcatt aacccagggt gtaccttctt ttatgcaggt gctgggcgtc gtcacaaatg
    26701 aaatgcaggt cgaggcggcc attatcgcgg aagagatcaa acaccataat ccgcaactcc
    26761 acgaaacgtt gctcactcac cttgagcagc tgcaaaaaca ccagggaaat accattgaaa
    26821 ttcgttacac cacgcatgaa caattcaaac aacaaaccgc agaaagtcag gcggtaattc
    26881 gcagcggaga atgttctccg tatgcgaata tcattctctg tgctggcgtg acgttctgag
    26941 gccgtcatgg aagcattact tcagcttaaa ggcatcgata aagccttccc gggcgtaaaa
    27001 gccctctcgg gcgcagcgtt aaatgtctat ccgggccgcg tgatggcgct ggtgggcgaa
    27061 aacggcgcgg gtaaatccac catgatgaaa gtgcttactg gcatctatac tcgcgatgcc
    27121 ggtacgcttt tatggctggg gaaagaaacg acatttaccg ggccaaaatc ttcccaggaa
    27181 gccgggattg ggattatcca tcaggaactg aacctgatcc cgcagttgac cattgccgaa
    27241 aacattttcc tcggtcgtga gtttgttaat cgctttggca aaattgactg gaaaaccatg
    27301 tatgccgaag cggataaatt gctggctaaa cttaacctgc gctttaaaag cgacaagctg
    27361 gtgggcgatc tttccatcgg tgaccagcaa atggttgaaa tcgccaaagt gctgagcttt
    27421 gagtcgaaag tcatcattat ggatgaaccg accgatgcgc tgaccgatac cgaaaccgaa
    27481 tccctgttcc gcgtcatccg cgagctgaaa tcgcaaggcc gcggtattgt ctatatctcc
    27541 caccgcatga aagaaatctt cgagatttgc gatgacgtta ccgtttttcg tgatgggcaa
    27601 tttattgctg agcgcgaagt ggcatcactg accgaagatt cgctgattga gatgatggtg
    27661 ggtcgcaagc tggaagatca atatccgcac ctggacaaag cgccgggaga tatccgcctg
    27721 aaagtcgata atctctgcgg acctggcgtt aacgatgtct cttttacttt acgcaaaggc
    27781 gaaattcttg gcgtctctgg tttgatgggc gcaggtcgta ccgaactgat gaaagtgctc
    27841 tacggcgcac taccgcgcac cagcggttac gtcaccctgg atgggcatga agtcgttacc
    27901 cgttcaccgc aggatggcct ggcaaacggc attgtgtata tctccgaaga ccgtaaacgt
    27961 gacggtttag tgttgggcat gtcagtaaaa gagaacatgt cgctgacagc gctgcgctac
    28021 ttcagccgcg ctggcggcag tttgaagcat gccgatgaac agcaggctgt gagtgatttc
    28081 attcgtctgt ttaatgtgaa aactccgtcg atggaacagg caattggtct gctttccggt
    28141 ggcaatcagc aaaaagtggc gattgcccgc ggtctgatga cacgccccaa agtgttgatc
    28201 cttgatgaac ctacccgtgg cgtagatgtc ggcgcgaaaa aagagatcta tcaactgatt
    28261 aaccagttca aagccgatgg cttgagcatc attctggtgt catcggagat gccagaagta
    28321 ttaggcatga gcgatcgcat catcgtcatg catgaagggc atctcagcgg ggaatttact
    28381 cgtgagcagg ccacccagga agtgttaatg gctgccgctg tgggcaagct taatcgcgtg
    28441 aatcaggagt aaaaaaatga caacccagac tgtctctggt cgccgttatt tcacgaaagc
    28501 gtggctgatg gagcagaaat cgcttatcgc tctgctggtg ctgatcgcga ttgtctcgac
    28561 gttaagcccg aactttttca ccatcaataa tttattcaat attctccagc aaacctcagt
    28621 gaacgccatt atggcggtcg ggatgacgct ggtgatcctg acgtcgggca tcgacttatc
    28681 ggtaggttct ctgttggcgc tgaccggcgc agttgctgca tctatcgtcg gcattgaagt
    28741 caatgcgctg gtggctgtcg ctgctgctct cgcgttaggt gccgcaattg gtgcggtaac
    28801 cggggtgatt gtagcgaaag gtcgcgtcca ggcgtttatc gctacgctgg ttatgatgct
    28861 tttactgcgc ggcgtgacca tggtttatac caacggtagc ccagtgaata ccggctttac
    28921 tgagaacgcc gatctgtttg gctggtttgg tattggtcgt ccgctgggcg taccgacgcc
    28981 agtctggatc atggggattg tcttcctcgc ggcctggtac atgctgcatc acacgcgtct
    29041 ggggcgttac atctacgcgc tgggcggcaa cgaagcggca acgcgtcttt ctggtatcaa
    29101 cgtcaataaa atcaaaatca tcatctattc tctttgtggt ctgctggcat cgctggccgg
    29161 gatcattgaa gtggcgcgtc tctcctccgc acaacccacg gcggggactg gctatgagct
    29221 ggatgctatt gctgcggtgg ttctgggcgg tacgagtctg gcgggcggaa aaggtcgcat
    29281 tgttgggacg ttgatcggcg cattaattct tggcttcctt aataatggat tgaatttgtt
    29341 aggtgtttcc tcctattacc agatgatcgt caaagcggtg gtgattttgc tggcggtgct
    29401 ggtagacaac aaaaagcagt aataacgact acaggacatc ttgaatatga acatgaaaaa
    29461 actggctacc ctggtttccg ctgttgcgct aagcgccacc gtcagtgcga atgcgatggc
    29521 aaaagacacc atcgcgctgg tggtctccac gcttaacaac ccgttctttg tatcgctgaa
    29581 agatggcgcg cagaaagagg cggataaact tggctataac ctggtggtgc tggactccca
    29641 gaacaacccg gcgaaagagc tggcgaacgt gcaggactta accgttcgcg gcacaaaaat
    29701 tctgctgatt aacccgaccg actccgacgc agtgggtaat gctgtgaaga tggctaacca
    29761 ggcgaacatc ccggttatca ctcttgaccg ccaggcaacg aaaggtgaag tggtgagcca
    29821 cattgcttct gataacgtac tgggcggcaa aatcgctggt gattacatcg cgaagaaagc
    29881 gggtgaaggt gccaaagtta tcgagctgca aggcattgct ggtacatccg cagcccgtga
    29941 acgtggcgaa ggcttccagc aggccgttgc tgctcacaag tttaatgttc ttgccagcca
    30001 gccagcagat tttgatcgca ctaaaggttt gaacgtaatg cagaacctgt tgaccgctca
    30061 tccggatgtt caggctatat tcgcgcagaa tgatgaaatg gcgctgggcg cgctgcgcgc
    30121 actgcaaact gccggtaaat cggatgtgat ggtcgtcgga tttgacggta caccggatgg
    30181 cgaaaaagcg gtgaatgatg gcaaactagc agcgactatc gctcagctac ccgatcagat
    30241 tggcgcgaaa ggcgtcgaaa ccgcagataa agtgctgaaa ggcgagaaag ttcaggctaa
    30301 gtatccggtt gatctgaaac tggttgttaa gcagtagttt taatcaggtt gtatgacctg
    30361 atggtgacat aaatacgtca tcgacagatg aacgtgtaat ataaagaaaa gcagggcacg
    30421 cgccacccta acacggtggc gcattttatg gacatcccga atatgcaaaa cgcaggcagc
    30481 ctcgttgttc ttggcagcat taatgctgac cacattctta atcttcaatc ttttcctact
    30541 ccaggcgaaa ccgtaaccgg taaccactat caggttgcat ttggcggcaa aggcgcgaat
    30601 caggctgtgg ctgctgggcg tagcggtgcg aatatcgcgt ttattgcctg tacgggtgat
    30661 gacagcattg gtgagagcgt tcgccagcag ctcgccactg ataacattga tattactccg
    30721 gtcagcgtga tcaaaggcga atcaacaggt gtggcgctga tttttgttaa tggcgaaggt
    30781 gagaatgtca tcggtattca tgccggcgct aatgctgccc tttccccggc gctggtggaa
    30841 gcgcaacgtg agcgtattgc caacgcgtca gcattattaa tgcagctgga atcaccactc
    30901 gaaagtgtga tggcagcggc gaaaatcgcc catcaaaata agactatcgt tgcgcttaac
    30961 ccggctccgg ctcgcgaact tcctgacgaa ctgctggcgc tggtggacat tattacgcca
    31021 aacgaaacgg aagcagaaaa gctcaccggt attcgtgttg aaaatgatga agatgcagcg
    31081 aaggcggcgc aggtactgca tgaaaaaggt atccgtactg tactgattac tttaggaagt
    31141 cgtggtgtat gggctagcgt gaatggtgaa ggtcagcgcg ttcctggatt ccgggtgcag
    31201 gctgtcgata ccattgctgc cggagatacc tttaacggtg cgttaatcac ggcattgctg
    31261 gaagaaaaac cattgccaga ggcgattcgt tttgcccatg ctgccgctgc gattgccgta
    31321 acacgtaaag gcgcacaacc ttccgtaccg tggcgtgaag agatcgacgc atttttagac
    31381 aggcagaggt gacgcttggc tacaatgaaa gatgttgccc gcctggcggg cgtttctacc
    31441 tcaacagttt ctcacgttat caataaagat cgcttcgtca gtgaagcgat taccgccaaa
    31501 gttgaagcgg cgattaaaga actcaattac gcgccatcag ctctggcgcg tagcctcaaa
    31561 ctcaatcaaa cacataccat tggcatgttg atcactgcca gtaccaatcc tttctattca
    31621 gaactggtgc gtggcgttga acgcagctgc ttcgaacgcg gttatagtct cgtcctttgc
    31681 aataccgaag gcgatgaaca gcggatgaat cgcaatctgg aaacgctgat gcaaaaacgc
    31741 gttgatggct tgctgttact gtgcaccgaa acgcatcaac cttcgcgtga aatcatgcaa
    31801 cgttatccga cagtgcctac tgtgatgatg gactgggctc cgttcgatgg cgacagcgat
    31861 cttattcagg ataactcgtt gctgggcgga gacttagcaa cgcaatatct gatcgataaa
    31921 ggtcataccc gtatcgcctg tattaccggc ccgctggata aaactccggc gcgcctgcgg
    31981 ttggaaggtt atcgggcggc gatgaaacgt gcgggtctca acattcctga tggctatgaa
    32041 gtcactggtg attttgaatt taacggcggg tttgacgcta tgcgccaact gctatcacat
    32101 ccgctgcgtc ctcaggccgt ctttaccgga aatgacgcta tggctgttgg cgtttaccag
    32161 gcgttatatc aggcagagtt acaggttccg caggatatcg cggtgattgg ctatgacgat
    32221 atcgaactgg caagctttat gacgccacca ttaaccacta tccaccaacc gaaagatgaa
    32281 ctgggggagc tggcgattga tgtactcatc catcggataa cccagccgac ccttcagcaa
    32341 caacgattac aacttactcc gattctgatg gaacgcggtt cggcttagat ttacgctgtc
    32401 ttttgatcaa attattacca tcggttgttt tcagaagcat gaacattgct gctgaagcaa
    32461 cagtaataat gcccattgtg ataaacgtat agtggaattg ttcgacagtc gttgtgcctt
    32521 ccattccttc ataaacgcga aggacggccg cacttacagc aacgcctaaa ctaatcgaca
    32581 gttgctgcgt gaccgccaga acactgttac cgctgctggc attgtcatcg gtcagatcgg
    32641 caagtgtgat ggtattcatc gcggtaaact gcgtcgacat agccatccct aatataaaca
    32701 acggcaagat cagcatccat atagccattg ctggtgattg caaagagaac tgagcgatca
    32761 ttagcccaat aatcaccgtg atccccacta acgtatggcg atagcccaga cgacgtaaga
    32821 cttgggtaac catcgatttt gcaataatgg aacctaacgc tgtcggtgcc atcatacagc
    32881 cagccataaa cgcctgataa ccaaatccta cctgtaacat caatggcata aggaacggta
    32941 cacagccggt ccccagacgg gttgcaatat tgcctacgat accgatcgag aaagtgcggg
    33001 ttttaaataa atctaatgaa attaatgggt ttggcgtgcg tcgtgcatgg agaatataga
    33061 gaagcagtaa cccgatgctg gtgacaatta ccgtcaaggc aatccagctg gcgacaatct
    33121 tttccccgaa tagctctatt ccgcttgaga agagaacaag gctgaggcca aacagcaaaa
    33181 agccagtgat atcgaatctg cgtcgtgcgg tggtgaaatt gggcatatgt ttgcgcgcgt
    33241 aaagaaggcc cgcaatacct atggggatat tgattaaaaa tatccagtgc caggttgccc
    33301 aggtgaccag cacgccgcca agaacggggc ctaaaattgg ccccaccaga cccggcatgg
    33361 cgacaaaatt caatactgga agaagttcat tacgaggata agcgcgcagt aaggccagcc
    33421 gagcaacagg catcatcatt gcgccgccta tcccctgaat aacccggaag acaaccagct
    33481 gtggtagcga attagaaagt gcgcaggcca gagaacccaa tgtgaacaga ctcacggcaa
    33541 gggtaaaaat gcgacgcgta ccgaagcgat cggctagcca tccgcttacc ggaataagca
    33601 tcgccaccgt cagcgtataa ctgatgatgg ctgattgcat cgcgagagga gaacgattaa
    33661 ggctatgagc gattgcgggt aaggcggtat taagaatagt ggcatcaagt gcctgcatga
    33721 agaaggccat cgccgcgatc cacggcaaac ccgccatact gcgcttcttt ttatcgctca
    33781 ttcaatgtcc tgttatcggg ttatcactta tcaggtgagc gtagcagcgc ctgacaagct
    33841 ttaaatgccg cgtcgccatc gctttggata atcgcatcga caatcgcctg atgcagatcc
    33901 agctttatca ctgtgtcgct ggtaattgac gtgaagtaag tgtgataaac cgaatggaat
    33961 agcgaggcga atgaggtcaa aaacggattg gcgctcattt catagatatg ctcatgccag
    34021 gccatatcga cttcgatcca gcgttcacgg cgaaagttct cttttaatgc cgccatttcg
    34081 gccattaacg tattgagatg cgctttctgt tccgcggtgc caaccgttgc tgccagtagg
    34141 caggcttgcg gctccagaca gatacgcata accagaaagt gatcgatgac ctgatgaaag
    34201 ttctcttctg tcatccacca ggtaagcaat tcctgatcaa gaaaattcca gttcgattgt
    34261 ggcatgaccc gagtaccaat tcgcggtcgc ggtaaaacca tcccttttgc cgttaacgtt
    34321 ttgaccgctt cgcgtaccgc tgtacgactc actccaaatt gctcgcccag ctcaatctca
    34381 ccgggcaaaa tggtgccggg ttcatattca ccttttaaga tccgttgcgc cagcttctca
    34441 gccagaacat acgaaaggtt tttctgtgca gctaactgtt gtgcgcttaa aggcattact
    34501 tatcttcctt tttcttttta ttcctcctta gtatgccacc aggaagtgtg attacggttg
    34561 caaaaacggc aaattgcttg ttttatggca cattaacggg gcttttgct
//
LOCUS       DACAOP010000044        33041 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.044, whole genome shotgun sequence.
ACCESSION   DACAOP010000044 DACAOP010000000
VERSION     DACAOP010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33041
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.044"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(696..771)
                     /locus_tag="IT892_002358"
     tRNA            complement(696..771)
                     /locus_tag="IT892_002358"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(736..738),aa:Ile,seq:cat)
     gene            1331..3583
                     /locus_tag="IT892_002359"
     CDS             1331..3583
                     /locus_tag="IT892_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135570.1"
                     /translation="MFSIKPGPRNLPIGNPTLLSWNITDGDLNSKLNTLEYLNCITNI
                     INSCGVYPQDLKDREIISTFHAEKVINDLLKNDYKISLFPDTTYRELNKAAQRSITAP
                     DRIGEGKTWVYQRDTMVERGDNSGVHQYGPAEHFTHIISDKPSPKDKYVAYAINIPDY
                     ELAADVYNINVTSPTGQQETFKILINPEHLRQTLERKSLTAVQKSQCEIITPKKPGEA
                     ILHAFNATYQQIRKNISEFARCHYGYIQIPPVTTFRADGPETPEEEKGYWFHAYQPED
                     LCTIHNPMGDLQDFIALVKDAKKFGIDIIPDYTFNFMGIGGSGKNDLDYPSADIRAKI
                     SKDIESGIPGYWQGQVLIPFIIDPVTKERDQIHPEDIHLTAKDFEASKDNISKDEWEN
                     LHALKEKRLNGMPKTTPKSDQVIMLQNQYVREMRKYGVRGLRYDAAKHSKHEQIERSI
                     TPPLKNYNERLHNTNLFNPKYQKKAVMNYMEYLVTCPLDEQQMSSLLYERDDLSAIDF
                     SLLMKTIKAFSFGGDLQTLASKPGSTISSIPSERRILININHDFPNNGNLFNDFLFNH
                     QQDEQLAMAYMAALPFSRPLVYWDGQVLKSTTEIKNDDGSTRVGGEAWLNKGCSTYQQ
                     LYNEFHALYIDKAGIWSAFEGVFATKNVLAFSRGDSVNINHSPHDGLVIINKGNEEVE
                     GTWPNKLQPGIYKNMGSNSVNIIINNTRKIIPPGKAFTLRGGTLNINIPGRSALLLGK
                     TGEPPNYLYL"
     gene            3920..4897
                     /gene="csiD"
                     /locus_tag="IT892_002360"
     CDS             3920..4897
                     /gene="csiD"
                     /locus_tag="IT892_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417145.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation induced protein CsiD"
                     /protein_id="HAP3135571.1"
                     /translation="MNALTAVQNNAVDSGQDYSGFTLTPSAQSPRLLELTFTEQTTKQ
                     FLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGV
                     DDVKQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELH
                     NDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDHYFRHPLARRPMRFAAPP
                     SKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSQGILSVP
                     VPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATNHYQTHQ"
     gene            4917..6185
                     /gene="lhgO"
                     /locus_tag="IT892_002361"
     CDS             4917..6185
                     /gene="lhgO"
                     /locus_tag="IT892_002361"
                     /EC_number="1.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="HAP3135572.1"
                     /translation="MYDFVIIGGGIIGMSTAMQLIDVYPDARIALLEKESGPACHQTG
                     HNSGVIHAGVYYTPGSLKAQFCLAGNRATKAFCDQNGIRYDNCGKMLVATSELEMERM
                     RALWERTAANGIEREWLNAEELREREPNITGLGGIFVPSSGIVSYREVTAAMAKIFQA
                     RGGEIIHNAEVSALSEHKNGVVIRTRQGGEYEASTLISCSGLMADRLVKMLSLEPGFI
                     ICPFRGEYFRLAPEHNQIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLAFKR
                     EGYRKRDFSFSDTLEILGSSGIRRVLQNHLRSGLGEMKNSLCKSGYLRLVQKYCPRLS
                     LSDLQPWPAGVRAQAVSPDGKLIDDFLFVTTPRTIHTCNAPSPAATSAIPIGAHIVSK
                     VQTLLASQSNPGRTLRAARSVDALHAAFNQ"
     gene            6208..7656
                     /gene="gabD"
                     /locus_tag="IT892_002362"
     CDS             6208..7656
                     /gene="gabD"
                     /locus_tag="IT892_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HAP3135573.1"
                     /translation="MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPK
                     MGADETRAAIDAANRALPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPL
                     AEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPA
                     AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGN
                     ELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEG
                     ALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQAVSKLHIGDGLENGVTIGPLIDE
                     KAVAKVEEHIADALEKGARVVCGGKADERGGNFFQPTILVDVPANAKVSKEETFGPLA
                     PLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVA
                     PFGGIKASGLGREGSKYGIEDYLEIKYMCIGL"
     gene            7670..8950
                     /gene="gabT"
                     /locus_tag="IT892_002363"
     CDS             7670..8950
                     /gene="gabT"
                     /locus_tag="IT892_002363"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HAP3135574.1"
                     /translation="MSSNKELMQRRSQAIPRGVGQIHPIFADRAENCRVWDVEGREYL
                     DFAGGIAVLNTGHLHPKVVAAVEAQLKKLSHTCFQVLAYEPYLELCEIMNQKVPGDFA
                     KKTLLVTTGSEAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMG
                     LMPGHVYRALYPCPLHGISEDDAIASIHRIFKNDAAPEDIAAIVIEPVQGEGGFYAAT
                     PAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLTTFAKSIAGGFPL
                     AGVTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKANDLGQKLKDG
                     LLAIAEKHTEIGDVRGLGAMIAIELFEDGDHSKPDAKLTAEIVARARDKGLILLSCGP
                     YYNVLRILVPLTIEDAQIRQGLEIISQCFAEAKQ"
     gene            9188..10588
                     /gene="gabP"
                     /locus_tag="IT892_002364"
     CDS             9188..10588
                     /gene="gabP"
                     /locus_tag="IT892_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GABA permease"
                     /protein_id="HAP3135575.1"
                     /translation="MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAG
                     PAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFW
                     VLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKV
                     IAILAFIFLGAVAISGFYPYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAE
                     IVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSV
                     LELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTP
                     YVAVLLSTGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAE
                     GSEIRLRMWLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMAR
                     WKKLVLWQKTPVHNTR"
     gene            10609..11271
                     /gene="csiR"
                     /locus_tag="IT892_002365"
     CDS             10609..11271
                     /gene="csiR"
                     /locus_tag="IT892_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CsiR"
                     /protein_id="HAP3135576.1"
                     /translation="MTITSLDGYRWLKNDIIRGNFQPDEKLRMSLLTSRYALGVGPLR
                     EALSQLVAERLVTVVNQKGYRVASMSEQELLDIFDARANMEAMLVSLAIARGGDEWEA
                     DVLAKAHLLSKLEACDASEKMLDEWDLRHQAFHTAIVAGCGSHYLLQMRERLFDLAAR
                     YRFIWLRRTVLSVEMLEDKRDQHQTLTAAVLARDTARASELMRQHLLTPIPIIQQAMA
                     GN"
     gene            complement(11272..11721)
                     /gene="kbp"
                     /locus_tag="IT892_002366"
     CDS             complement(11272..11721)
                     /gene="kbp"
                     /locus_tag="IT892_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium binding protein Kbp"
                     /protein_id="HAP3135577.1"
                     /translation="MGLFNFVKDAGEKLWDAVTGQHDKDDQAKKVQEHLNKTGIPDAD
                     KVNIQIADGKATVTGDGLSQEAKEKILVAVGNISGIASVDDQVKTVTPATASQFYTVK
                     SGDTLSAISKQVYGNANLYNKIFEANKPMLKSPDKIYPGQVLRIPEE"
     gene            complement(11805..11963)
                     /locus_tag="IT892_002367"
     CDS             complement(11805..11963)
                     /locus_tag="IT892_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="HAP3135578.1"
                     /translation="MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIH
                     AFWVQTRD"
     gene            12146..12445
                     /locus_tag="IT892_002368"
     CDS             12146..12445
                     /locus_tag="IT892_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP3135579.1"
                     /translation="MTELAQLQASAEQAAALLKAMSHPKRLLILCMLSGSPGTSAGEL
                     TRITGLSASATSQHLARMRDEGLIDSQRDAQRILYSIKNEAVNAIIATLKNVYCP"
     gene            12455..12979
                     /gene="ygaP"
                     /locus_tag="IT892_002369"
     CDS             12455..12979
                     /gene="ygaP"
                     /locus_tag="IT892_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YgaP"
                     /protein_id="HAP3135580.1"
                     /translation="MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLS
                     VLEQSGLPAKLRREQIIFHCQAGKRTSNNADKLAAIAAPAEIFLLEDGIDGWKKAGLP
                     VAVNKSQPLPLMRQVQIAAGGLILIGVVLGYTVNSGFFLLSGFVGAGLLFAGISGFCG
                     MARLLDKMPWNQRA"
     gene            complement(13026..13430)
                     /gene="stpA"
                     /locus_tag="IT892_002370"
     CDS             complement(13026..13430)
                     /gene="stpA"
                     /locus_tag="IT892_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein StpA"
                     /protein_id="HAP3135581.1"
                     /translation="MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEE
                     EQQQRELAERQEKISTWLELMKADGINPEELLGNSSAAAPRAGKKRQPRPAKYKFTDV
                     NGETKTWTGQGRTPKPIAQALAEGKSLDDFLI"
     gene            14097..14546
                     /gene="alaE"
                     /locus_tag="IT892_002371"
     CDS             14097..14546
                     /gene="alaE"
                     /locus_tag="IT892_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-alanine exporter AlaE"
                     /protein_id="HAP3135582.1"
                     /translation="MFSPQSRLRHAVADTFAMVVYCSVVNMCIEVFLSGMSFEQSFYS
                     RLVAIPVNILIAWPYGMYRDLFMRAARKVSPSGWIKNLADIMAYVTFQSPVYVAILLV
                     VGADWHQIMAAVSSNIVVSMLMGAVYGYFLDYCRRLFKVSRYQQVKA"
     gene            complement(14583..14927)
                     /locus_tag="IT892_002372"
     CDS             complement(14583..14927)
                     /locus_tag="IT892_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgaC family protein"
                     /protein_id="HAP3135583.1"
                     /translation="MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARM
                     GRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVAL
                     ERYLNGLFGEAS"
     gene            15079..15408
                     /locus_tag="IT892_002373"
                     /pseudo
     CDS             15079..15408
                     /locus_tag="IT892_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311560.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
     gene            15656..15901
                     /gene="nrdH"
                     /locus_tag="IT892_002374"
     CDS             15656..15901
                     /gene="nrdH"
                     /locus_tag="IT892_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAP3135584.1"
                     /translation="MRITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAAEALR
                     AQGFRQLPVVIAGDLSWSGFRPDMINRLHPAPHAASA"
     gene            15898..16299
                     /gene="nrdI"
                     /locus_tag="IT892_002375"
     CDS             15898..16299
                     /gene="nrdI"
                     /locus_tag="IT892_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAP3135585.1"
                     /translation="MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYIL
                     IVPSYGGGGTAGAVPRQVIRFLNNEHNRVLLRGVIASGNRNFGEAYGRAGDVIARKCG
                     VPWLYRFELMGTQSDIENVRKGVTEFWQRQP"
     gene            16281..18425
                     /gene="nrdE"
                     /locus_tag="IT892_002376"
     CDS             16281..18425
                     /gene="nrdE"
                     /locus_tag="IT892_002376"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAP3135586.1"
                     /translation="MATTTVERLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAF
                     ITTHVRPNSVAFSSQQQRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHASGFRFQTF
                     LGAWKFYTSYTLKTFDGKRYLEDFTDRVTMVALTLAQGDETLAAQLTDEMLSGRFQPA
                     TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAG
                     APIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKREN
                     ADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGKPFADIAISEHYAEL
                     VANERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEIL
                     QVNSASEYDENLDYARTGHDISCNLGSLNIAHTMDSPDFARTVETAVRGLTAVSDMSH
                     IRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYTITWHALRT
                     SMLLARERSETFAGFKQSRYANGEYFSQYLQGNWQPKTAKVGELFARSGITLPTREMW
                     AQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPA
                     PFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIY
                     AWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL"
     gene            18435..19394
                     /gene="nrdF"
                     /locus_tag="IT892_002377"
     CDS             18435..19394
                     /gene="nrdF"
                     /locus_tag="IT892_002377"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAP3135587.1"
                     /translation="MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPA
                     WQTLSVVEQQLTMRVFTGLTLLDTLQNVIGAPSLLPDALTPHEEAVLSNISFMEAVHA
                     RSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
                     LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNMEKISQAQREEL
                     KSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYNANKALMNLGYEPLFPAEMA
                     EVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF"
     gene            19751..20953
                     /locus_tag="IT892_002378"
     CDS             19751..20953
                     /locus_tag="IT892_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline/glycine betaine ABC transporter
                     ATP-binding protein ProV"
                     /protein_id="HAP3135588.1"
                     /translation="MAIKLEIKNLYKIFGEHPQRAFKYIEQGLSKEQILEKTGLSLGV
                     KDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELRE
                     VRRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHS
                     YPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTI
                     VFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQVFSA
                     KDIARRTPNGLIRKTPGFGPRSALKLLQDEDREYGYVIERGNKFVGAVSIDSLKTALT
                     QQQGLDAALIDAPLAVDAQTPLSELLSHVGQAPCAVPVVDEDQQYVGIISKGMLLRAL
                     DREGVNNG"
     gene            20946..22010
                     /gene="proW"
                     /locus_tag="IT892_002379"
     CDS             20946..22010
                     /gene="proW"
                     /locus_tag="IT892_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /protein_id="HAP3135589.1"
                     /translation="MADQNNPWDTTPAADSAAQSADAWGTPAAAPTDGGGADWLTSTP
                     APNVEHFNILDPFHKTLIPLDSWVTEGIDWVVTHFRPVFQGVRVPVDYILNGFQQLLL
                     GMPAPVAIIVFALIAWQISGVGMGVATLVSLIAIGAIGAWSQAMVTLALVLTALLFCI
                     VIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFA
                     LPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLAL
                     SMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSR
                     GNRRWYTTGPVGLLTRPFIK"
     gene            22068..23060
                     /gene="proX"
                     /locus_tag="IT892_002380"
     CDS             22068..23060
                     /gene="proX"
                     /locus_tag="IT892_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     substrate-binding protein ProX"
                     /protein_id="HAP3135590.1"
                     /translation="MRHSVLFATAFATLISTQTFAADLPGKGITVNPVQSTITEETFQ
                     TLLVSRALEKLGYTVNKPSEVDYNVGYTSLASGDATFTAVNWTPLHDNMYEAAGGDKK
                     FYREGVFVNGAAQGYLIDKKTADQYKITNIAQLKDPKIAKLFDTNGDGKADLTGCNPG
                     WGCEGAINHQLAAYGLTNTVTHNQGNYAAMMADTISRYKEGKPVFYYTWTPYWVSNEL
                     KPGKDVVWLQVPFSALPGDKNADTKLPNGANYGFPVSTMHIVANKAWAEKNPAAAKLF
                     AIMQLPVADINAQNAIMHDGKASEGDIQGHVDGWIKAHQQQFDGWVNEALAAQK"
     gene            23513..24697
                     /locus_tag="IT892_002381"
     CDS             23513..24697
                     /locus_tag="IT892_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3135591.1"
                     /translation="MTKPNHELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLS
                     ASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLITASSQSLAMM
                     ILGTALTGLFSVVAQILVPLAATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANL
                     GGWRTVFWVASVLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISDKILRTRAL
                     LGCLTFANFSILWTSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKS
                     HHTTTFGLLLLLLSWLAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDAR
                     NRLTAGYMTSYFIGGAAGSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEA
                     AN"
     gene            24821..25558
                     /locus_tag="IT892_002382"
     CDS             24821..25558
                     /locus_tag="IT892_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAP3135592.1"
                     /translation="MESPTPQPAPGSATFMEGCKDSLPIVISYIPVAFAFGLNATRLG
                     FSPLESVFFSCIIYAGASQFVITAMLAAGSSLWVAALTVMAMDVRHVLYGPSLRSRII
                     QRLQKSKTALWAFGLTDEVFAAATAKLVRNNRRWSENWMIGIAFSSWSSWVFGTVIGA
                     FSGSGLLQGYPAVEAALGFMLPALFMSFLLASFQRKQSLCVTAALVGALAGVTLFSIP
                     VAILAGIVCGCLTALIQAFWQGAPDEL"
     gene            25548..25883
                     /gene="ygaH"
                     /locus_tag="IT892_002383"
     CDS             25548..25883
                     /gene="ygaH"
                     /locus_tag="IT892_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine transporter subunit YgaH"
                     /protein_id="HAP3135593.1"
                     /translation="MSYEVLLLGLLVGAANYCFRYLPLRLRVGNARPTKRGAIGILLD
                     TIGIASICALLVVSTAPEVMHDTRRFVPTLVGFAVLGASFYKTRSIIIPTLLSALAYG
                     LAWKVMAII"
     gene            complement(25902..26003)
                     /locus_tag="IT892_002384"
     CDS             complement(25902..26003)
                     /locus_tag="IT892_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135594.1"
                     /translation="MFNGRKRTIHLGMTSLISADIVTTVTNKVNVLF"
     gene            25974..26504
                     /gene="emrR"
                     /locus_tag="IT892_002385"
     CDS             25974..26504
                     /gene="emrR"
                     /locus_tag="IT892_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter EmrAB
                     transcriptional repressor EmrR"
                     /protein_id="HAP3135595.1"
                     /translation="MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENR
                     NKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIE
                     RRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
                     RLDQMEQDGVVLEAMS"
     gene            26631..27803
                     /gene="emrA"
                     /locus_tag="IT892_002386"
     CDS             26631..27803
                     /gene="emrA"
                     /locus_tag="IT892_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrA"
                     /protein_id="HAP3135596.1"
                     /translation="MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFL
                     VLRHFEETDDAYVAGNQIQTMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFE
                     KAKTALASSVRQTHQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREEL
                     QHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRI
                     VSPMTGYVSRRAVQPGAQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQPVTITT
                     DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYP
                     LRIGLSTLVSVNTTNRDGQVLANKVRSTPVAVSTAREISLAPVNKLIDDIVKANAG"
     gene            27820..29358
                     /gene="emrB"
                     /locus_tag="IT892_002387"
     CDS             27820..29358
                     /gene="emrB"
                     /locus_tag="IT892_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrB"
                     /protein_id="HAP3135597.1"
                     /translation="MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNL
                     GSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSL
                     NMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
                     ISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQI
                     MLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLC
                     ISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMR
                     RLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPP
                     ERLAAASSLSNFTRTLAGSIGTSITTTMWTNRESMHHAQLTESVNPFNPNAQAMYSQL
                     EGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGG
                     GGAH"
     gene            complement(29422..29937)
                     /gene="luxS"
                     /locus_tag="IT892_002388"
     CDS             complement(29422..29937)
                     /gene="luxS"
                     /locus_tag="IT892_002388"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008458247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAP3135598.1"
                     /translation="MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPN
                     KEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
                     AWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELA
                     LPKEKLQELHI"
     gene            complement(30087..31643)
                     /gene="gshA"
                     /locus_tag="IT892_002389"
     CDS             complement(30087..31643)
                     /gene="gshA"
                     /locus_tag="IT892_002389"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HAP3135599.1"
                     /translation="MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGRLATTGH
                     PEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPL
                     SMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
                     QAKCGDIAGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPF
                     EKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAK
                     IGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDI
                     NPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSRELACTRVNWNRVILEGRKPGLTLG
                     IGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSAR
                     ILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTE
                     PFAVWLEKHA"
     gene            complement(31716..32144)
                     /locus_tag="IT892_002390"
     CDS             complement(31716..32144)
                     /locus_tag="IT892_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HAP3135600.1"
                     /translation="MSEALSLFSLFASSFLSATLLPGNSEVVLVAMLLSGISHPWVLV
                     LTATMGNSLGGLTNVILGRFFPLRKTSRWQEKATGWLKRYGAVTLLLSWMPVVGDLLC
                     LLAGWMRISWGPVIFFLCLGKALRYVAVAAATVQGMMWWH"
     gene            complement(32141..32707)
                     /gene="yqaB"
                     /locus_tag="IT892_002391"
     CDS             complement(32141..32707)
                     /gene="yqaB"
                     /locus_tag="IT892_002391"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1-phosphate/6-phosphogluconate
                     phosphatase"
                     /protein_id="HAP3135601.1"
                     /translation="MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMI
                     ALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVRSMLLDSVEPLPLVEVVKSWHGR
                     RPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
                     QCVVFEDADFGILAARAAGMDAVDVRLL"
     gene            complement(32918..32994)
                     /locus_tag="IT892_002392"
     tRNA            complement(32918..32994)
                     /locus_tag="IT892_002392"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32958..32960),aa:Arg,seq:acg)
BASE COUNT         8195 a         8290 c         8256 g         8300 t
ORIGIN      
        1 aaaaaatcgc tcatttgaga caattgctgg cattaacagc ttcatatgct atacatggca
       61 cttttaatta atttagcaca ggaatgttaa atttaataaa caaaaggtta tttcactgta
      121 tgataaaaac cacccgttat aatttattcg tgagaatcgt tttttgagtg ttagaaattt
      181 atatctaaat agcgttgatt aatgaccaaa gccagactcc tgtaatgctc acaagactct
      241 tctgcattcg acggcggttc tagtcagtag tagatgttta aggcgtggca gagacatttc
      301 atccttactc tacggcattg gtccacatac aaatcgtggt tgtgacactt cacttatcat
      361 cagtgagcga acagagaata gttcagtgat ttgagtaatt aacctgatta aatgaagagg
      421 catgataaat gataatactc tggctttatc gttaattact taattccaca tgtaagcaat
      481 ttgcccgctt ggcatagcgg gcattttttc caggtacttt tgaatgagta ctgatggata
      541 aatacattgc agtggcgtgc cacgtaccaa aacaccagcc ctcattcgaa actacctacc
      601 gcactgcttc tttaaaatgg cgttagtcgt gaaatattga ccgccatcga gtcccccttg
      661 taaccttaac tcttcctgat acgtgaataa tgatttggtg gcccttgctg gacttgaacc
      721 agcgaccagg cgattatgag tcgtctgctc taaccactga gctaaagggc cttgagtatg
      781 caataacaat acttatatac cacgcaataa acatgatgat cttatgatgt aaataacaga
      841 tttttatgcg ttctcattca tcctgggtcg tcattacctg cgacataaaa cccgacacca
      901 cttccattca caaagtcgat actctcagtc aacaagcaaa tgctaatact tagcactatt
      961 tatagttacc atcgattcaa tgatagtttg taatgatttt gtatctaata atataacttt
     1021 attacattaa ctgaagagtt ttcgcatcat tatgatatct gttacttttc acgccataaa
     1081 aataaacttc atatagcaat atattctttc atagatctta ttctgctaat cattagtttc
     1141 gtatgagcga tttttgacag ttgcctctcc agaccacatc gataattaaa aaaacagatt
     1201 taagcattat ccttttccat ataaatattg gataaaagta ggacatctgt ttgcaattac
     1261 tttcacaaca attaaacatt tttatgtttc cgtatacacc atattactct accattagag
     1321 gaactttatt atgttttcta taaaaccagg accaagaaat ttacctatcg gcaaccccac
     1381 attgttatca tggaacatta ctgacgggga tctaaattcc aaattaaata cattagaata
     1441 tctaaactgt ataacaaata ttattaattc ttgtggagtt tatcctcagg atttaaaaga
     1501 cagagaaatt atatcaactt ttcacgcaga aaaagttatt aatgatctgt taaaaaacga
     1561 ttataaaatt tccctttttc cagatacaac ttaccgagag ttgaataaag cagcacagcg
     1621 tagcattaca gcgccagaca ggataggaga aggaaaaaca tgggtttatc aacgagatac
     1681 aatggttgaa agaggtgata acagcggtgt tcatcagtat ggtccagctg aacattttac
     1741 tcacattata tctgacaaac cgtccccaaa agataagtat gttgcatatg ctattaacat
     1801 tcctgactat gaactggcag ctgatgtata taatattaac gtaacgtcac ctaccggcca
     1861 gcaagaaaca tttaaaatat taatcaatcc agaacatcta cggcaaacac ttgagcgtaa
     1921 atctcttact gctgttcaga aatcacaatg tgaaatcatc acccccaaaa aacctggcga
     1981 agcgattctt catgctttta atgccaccta tcaacaaatc aggaaaaata tatctgagtt
     2041 tgcacgttgt cattatgggt atatacaaat ccctcccgta accactttcc gcgccgacgg
     2101 accagaaact cccgaagaag aaaaaggtta ctggtttcac gcttatcaac ccgaagatct
     2161 ttgtactatt cataatccaa tgggagattt gcaggatttt atcgcattgg ttaaagatgc
     2221 caaaaaattt ggtatcgata tcatccctga ttatacattt aactttatgg gaatcggggg
     2281 tagtggtaaa aatgatctgg attatccctc tgccgatata cgagcgaaga tcagtaaaga
     2341 tatagaaagt ggtatccctg gctattggca aggtcaggtc ttgattccct ttattataga
     2401 tccagtaaca aaagaacgtg accaaatcca tccagaagat atacatctca ctgcaaaaga
     2461 cttcgaagca agtaaagata atatttctaa ggatgaatgg gaaaacctcc atgcattaaa
     2521 agaaaagcgt ttaaatggaa tgcctaaaac aacacccaaa agtgaccagg ttattatgtt
     2581 gcaaaatcaa tacgttcgtg aaatgcgaaa atatggcgta cgaggtttac gttatgatgc
     2641 agcaaaacac tcaaaacatg aacaaataga gaggtcgata accccaccgc ttaaaaatta
     2701 taatgagcgg ttgcacaata caaatttatt taatccaaaa tatcaaaaaa aagctgttat
     2761 gaattacatg gaatacctgg taacttgtcc gttagatgaa caacaaatgt catcgctgct
     2821 ttatgaaaga gatgatttaa gcgccattga tttttcattg ctcatgaaga cgataaaagc
     2881 cttttcattc ggtggcgatc tccaaactct tgcatcaaaa ccgggctcca caatctcaag
     2941 catcccatca gaaagacgga tattgattaa catcaaccac gatttcccta acaatggtaa
     3001 tcttttcaat gactttttat ttaaccatca gcaagatgaa caattagcaa tggcatatat
     3061 ggccgctctc ccgttcagca ggcctttagt ttactgggat ggtcaggtat taaaatcaac
     3121 gactgagatt aaaaatgatg atgggtccac tcgtgtcggc ggtgaggcgt ggcttaataa
     3181 aggttgctct acctatcagc agctctacaa tgaattccac gcattatata tagataaagc
     3241 aggaatatgg agcgcatttg agggggtatt tgcaactaaa aacgttctgg cctttagtcg
     3301 tggggattct gtgaacatta atcactctcc tcatgatgga ctagttataa taaataaagg
     3361 aaacgaagaa gttgaaggta cctggcctaa caaattgcaa cctggaatat ataaaaacat
     3421 ggggagtaat agcgttaaca ttattattaa taatacccga aaaattatcc cccctggtaa
     3481 agcatttacg cttagaggcg gaactctaaa tatcaatatt cctgggcgta gcgctcttct
     3541 tttagggaaa actggagaac cgccgaacta tctctatttg taatttaatg ttatatctgc
     3601 cccgctaaaa cggggcagat aatatgttta gtttactaac ggtcattttg cagtgaagcc
     3661 atttaccgtt ttttatcgac cagataatct gttctctgat ggtaatcccc ccctaacctg
     3721 ttgctttagt tattcatttc ctgtctcact ttgccttaat accctacgtt aaatgttacc
     3781 aatttgttgc ttttgatcac aataagaaaa caatatggcg catttgtgcg catttttcag
     3841 aaatgtagat atttttagat tatggctacg aaatgagcat cgccatgtca ccctacatct
     3901 cataagagga tcgcttctga tgaatgcact gaccgccgta caaaacaacg ctgtcgattc
     3961 aggccaggac tatagcggat tcaccctcac cccgtcggcg caatccccgc gcctgctgga
     4021 actcaccttc accgaacaga cgaccaaaca gtttctcgaa caggttgccg aatggcccgt
     4081 gcaggcgctg gagtacaaat cttttctgcg ttttcgggta ggcaaaattc ttgacgattt
     4141 gtgtgcgaac cagctgcaac cattgctgtt gaagaccctg ctaaaccgtg ctgaaggtgc
     4201 gctgttgatc aatgcggtgg gtgtcgatga tgtgaagcaa gcggatgaga tggtgaagct
     4261 ggcaacggcg gtagcgcatc tgattggtcg ctcaaatttc gatgcgatga gcggtcagta
     4321 ttacgcgcga ttcgtggtga aaaatgtcga taactcagac agctatctgc gtcagccgca
     4381 ccgcgtaatg gagctgcaca acgacggcac ctacgtcgaa gagatcaccg actatgtgct
     4441 gatgatgaaa atcgacgagc agaacatgca gggtggaaat tcgttgctgc tgcatctcga
     4501 tgactgggaa catctggacc actatttccg ccacccgctg gcgcgtcgcc cgatgcgctt
     4561 tgccgcgccg ccgagcaaaa acgtcagcaa agatgttttc catccagtgt tcgacgttga
     4621 tcaacagggt cgcccggtga tgcgttatat cgaccagttc gtccagccaa aagattttga
     4681 agaaggcgtg tggttgagcg agctttccga tgccattgaa accagccaag gcattctttc
     4741 tgtacccgtt cccgttggca aattcctgtt gataaacaac ctgttctggc tgcacggtcg
     4801 cgaccgcttt actccgcacc cggatctgcg ccgtgaactg atgcgtcagc gtggctattt
     4861 cgcttacgcc actaaccact accagacgca tcagtaagcg caaaggaatt gagcggatgt
     4921 atgattttgt gattattggc ggcggcatca tcggcatgtc gaccgccatg caactgattg
     4981 atgtctatcc ggatgcccgc attgcgttgc tggaaaaaga gtccggcccg gcctgtcacc
     5041 agacgggtca caacagcggc gtgatccatg ccggggtcta ttacacgccc ggcagcctaa
     5101 aggcgcagtt ttgcctggcg gggaaccgcg ccaccaaagc cttttgcgat caaaacggca
     5161 ttcgctatga caactgcggc aagatgctgg tcgccacctc tgaactcgaa atggaacgga
     5221 tgcgcgcgtt gtgggaacgc acggcggcga acggtatcga gcgcgagtgg ttaaacgccg
     5281 aggagctgcg cgagcgcgaa ccgaatatca ccgggctcgg cggcattttt gtgccgtcca
     5341 gcggcattgt cagctatcgc gaagtgacgg cggcgatggc aaaaatcttc caggccagag
     5401 gcggcgagat tattcataac gccgaagtca gcgccctcag tgagcataaa aacggcgtgg
     5461 tgatacgtac ccgtcagggc ggtgaatatg aagcatcgac gctgattagc tgttccgggc
     5521 tgatggctga ccggctggtg aaaatgctca gcctcgaacc gggctttatt atctgcccgt
     5581 tccgtggcga gtatttccgc cttgcgccgg agcataacca gattgttaac cacctgattt
     5641 accccattcc cgaccccgcg atgccatttt tgggcgtgca tctcacccgc atgatcgatg
     5701 gcagcgtgac cgtcgggcca aacgcggtgc tggcttttaa acgcgaaggc tatcgcaagc
     5761 gcgatttctc gtttagtgac acgctggaga ttttaggctc gtcggggatt cgccgggtgc
     5821 tgcaaaacca tctacgctca ggactgggcg agatgaaaaa ctcgctgtgc aaaagcggct
     5881 atttgcggct ggtgcaaaag tattgtcccc ggctttcgtt aagcgatctc cagccctggc
     5941 ccgccggtgt gcgggcgcag gcggtatcgc cggacggcaa gctgattgac gattttctgt
     6001 ttgtcaccac cccgcgcacg atccacacct gcaatgcgcc ctccccggca gcgacatcag
     6061 caattcctat tggtgcgcat attgtcagca aggtacaaac gctgttggca agccagagta
     6121 accccggacg cacgctgcga gcggcacgta gtgtggatgc cttacacgcc gcatttaatc
     6181 aataaccttt gaaaacagga cgtaacaatg aaacttaacg acagtaactt attccgccag
     6241 caggcgttga ttaacgggga atggctggac gccaacaatg gcgaggtcat cgacgtcacc
     6301 aatccggcga acggcgacaa gctgggtagc gtgcccaaaa tgggcgctga tgaaacccgc
     6361 gccgctatcg acgccgccaa ccgcgctctg cccgcctggc gtgcgctcac cgccaaagaa
     6421 cgcgccacca ttctgcgcaa ctggttcaat ttgatgatgg agcatcagga cgatttagcg
     6481 cgcctgatga ccctagaaca gggcaaaccg ctggctgaag cgaaaggcga aattagctac
     6541 gccgcctcct ttattgagtg gtttgccgaa gaaggcaaac gcatttatgg cgacaccatt
     6601 cctggtcatc aggccgataa acgcctgatt gttatcaagc agccgattgg cgtcaccgcg
     6661 gctatcacgc cgtggaactt cccggcggcg atgattaccc gcaaagccgg tccggcgctg
     6721 gcggcaggct gcaccatggt gctgaagccc gccagtcaga cgccgttctc tgcgctggcg
     6781 ctggcggagc tggcgattcg cgcaggcgtt ccggctggcg tatttaacgt ggtcaccggt
     6841 tcggcgggcg cggtcggtaa cgaactgacc agcaatccgc tggtgcgcaa gctgtcgttt
     6901 accggctcga ccgaaattgg ccgccagtta atggaacagt gcgcgaaaga catcaagaaa
     6961 gtgtcgctgg agctgggcgg caacgcgccg tttatcgtct ttgacgatgc cgacctcgac
     7021 aaagccgtgg aaggcgcact ggcctcgaaa ttccgcaacg ccgggcaaac ctgcgtctgc
     7081 gccaaccgtt tatacgtgca ggacggcgtg tatgaccgct ttgccgaaaa attacagcag
     7141 gcggtgagca aactgcacat cggcgacggg ctggagaatg gcgtcaccat cgggccgctg
     7201 attgatgaaa aagcggtagc aaaagtggaa gagcatattg ccgatgcgct ggagaaaggt
     7261 gcgcgtgtgg tttgcggcgg taaagcggat gaacgcggcg gcaacttctt ccagccgacc
     7321 attctggtgg acgttccagc caacgccaaa gtgtcgaaag aagagacgtt cggccccctc
     7381 gccccactgt tccgttttaa agatgaagcc gatgtgattg cgcaagccaa tgacaccgag
     7441 tttggtcttg ccgcctattt ctacgcccgt gatttaagcc gcgtcttccg cgtgggcgaa
     7501 gcgctggagt acggcatcgt cggcatcaat accggcatta tttccaatga agtggccccg
     7561 ttcggcggca ttaaagcctc gggtctgggt cgtgaaggtt cgaagtatgg catcgaagat
     7621 tacttagaaa tcaaatatat gtgcatcggt ctttaactgg agaacgcgaa tgagcagcaa
     7681 taaagagtta atgcagcgcc gcagtcaggc gattccccgt ggcgttgggc aaattcaccc
     7741 gattttcgct gaccgcgcgg aaaactgccg ggtgtgggac gttgaaggcc gtgagtatct
     7801 tgatttcgcg ggcgggattg cggtgctcaa taccgggcac ctgcatccga aagtggttgc
     7861 ggcagtggaa gcgcagttga aaaaactgtc gcacacctgc ttccaggtgc tggcctacga
     7921 gccgtatctg gagctgtgcg agattatgaa tcagaaggtg ccgggcgatt ttgccaagaa
     7981 aacgctgctg gttacgaccg gttccgaagc ggtggaaaac gcggtgaaaa tcgcccgtgc
     8041 cgccaccaaa cgtagcggta ccatcgcctt tagcggcgcg tatcacgggc gcacgcatta
     8101 cacgctggcg ctgaccggca aggtgaatcc gtactctgcg ggcatgggac tgatgcctgg
     8161 gcacgtttat cgcgcgcttt atccttgtcc gctgcacggc atcagtgaag atgacgctat
     8221 cgccagcatc caccggatct ttaaaaatga cgctgcgccg gaagatatcg ccgccatcgt
     8281 gattgagccg gttcagggcg aaggcggttt ctacgccgcg acgccagcct ttatgcagcg
     8341 tttacgcgcg ctgtgtgacg agcacgggat catgctgatt gccgatgaag tgcagagcgg
     8401 cgcggggcgt accggcacgc tgtttgcgat ggagcagatg ggcgttgcgc cggatcttac
     8461 cacctttgcg aaatcgatcg cgggcggctt cccgctggcg ggcgtcaccg ggcgcgcgga
     8521 agtgatggat gccgtcgctc caggcggtct gggcggcacc tatgcgggta acccgattgc
     8581 ctgcgtggct gcgctggaag tgttgaaggt gtttgagcag gaaaatctgc tacaaaaagc
     8641 caacgatctg gggcagaaac tgaaagacgg attgctggcg atagccgaaa aacatactga
     8701 gatcggcgac gtacgcgggc tgggagcgat gatcgccatc gagctgtttg aagatggcga
     8761 tcacagcaaa ccggacgcaa aactcaccgc cgagatcgtg gcgcgcgccc gcgataaggg
     8821 cctgattctt ctctcctgcg gcccgtatta caacgtgctg cgcatccttg taccgctcac
     8881 cattgaagac gctcagatcc gtcagggtct ggagatcatc agccagtgtt ttgcagaggc
     8941 gaagcagtag atccgtaccc atgccggagg cgacgctgcg cgtcttgtcc ggcctacgcg
     9001 aatccaggtc ggataaagcg tttacgctgc atccgacaat ctgtacgtga acaggaataa
     9061 atctatgtcg gccggataag gcggagccgc tctccggtaa aaagaaccaa taacaattac
     9121 acgcgtgacc cgacgcggga aatgtcgggg cgctctccca agtgacacac tttcgagagg
     9181 attcaggatg gggcaatcat cgcaaccaca tgagttaggc ggcgggctga agtcacgcca
     9241 cgtcaccatg ttgtctattg ccggtgttat cggcgcaagt ctgtttgtcg gttccagcgt
     9301 cgccatcgcc gaagcgggcc cggcggtatt actggcctat ctgttcgccg gattactggt
     9361 ggttatgatt atgcggatgt tggcggaaat ggcggttgcc acgcccgaca cgggttcgtt
     9421 ttccacctat gcagataaag ctattggtcg ttgggcgggc tataccatcg gctggttgta
     9481 ctggtggttt tgggtactgg ttatcccgct ggaagccaac atcgccgcca tgatcctgca
     9541 ctcgtgggtt ccaggcattc ccatctggtt attttccctc gtcattaccc tcgccttaac
     9601 tggcagtaat ttattaagcg ttaaaaacta cggcgaattt gagttctggc tggcgctgtg
     9661 caaagtcatc gctatcctgg cctttatttt ccttggtgca gtcgcaatta gcggttttta
     9721 cccttatgcc gaagtgagcg ggatctcaag attgtgggat agcggcggct ttatgcccaa
     9781 cggcttcggc gcggtattaa gcgcgatgtt gatcaccatg ttctcgttta tgggcgcaga
     9841 aattgtcacc attgccgccg cggaatccga cacgccggaa aaacatattg tccgcgctac
     9901 caactcggtt atctggcgta tttctatctt ctatttgtgc tctatttttg tcgtcgtggc
     9961 attaataccg tggaatatgc cggggctgaa agccgttgga tcttatcgct cggttctgga
    10021 attactcaat attccccatg cgaaattaat catggactgc gtgatattac tttccgtaac
    10081 cagctgtctg aactcggcgc tgtataccgc ttccagaatg ctctactcct taagccgtcg
    10141 cggtgatgct cccgcggtaa tgggtaaaat caaccgcagt aaaaccccgt atgtggcggt
    10201 attactctcg accggtgcgg catttttaac ggtggtggtg aattattacg cgcctgcgaa
    10261 agtgtttaaa tttctgatcg acagctccgg cgctatcgcc ctgctggttt atttagtcat
    10321 cgccgtttca caattgcgga tgcgcaaaat tctgcgagca gaaggaagcg aaattcgcct
    10381 gcggatgtgg ctttatccgt ggctcacctg gctggtcatc ggctttatta cctttgtgtt
    10441 ggtagtgatg ctattccgcc cggcgcaaca gttagaagtg atctccaccg gcttattagc
    10501 gatagggatt atctgtaccg tgccaattat ggctcgctgg aaaaagctgg tattgtggca
    10561 aaaaacaccc gttcataata cgcgctaata atgatcagga gtcacaccat gaccattacg
    10621 tctctggatg gctatcgctg gctgaagaac gatattattc gcggaaactt tcaaccggat
    10681 gaaaaattac ggatgagttt gctgacatcg cgttatgcac ttggcgttgg gccgttgcgg
    10741 gaagcgcttt cgcaactggt agcagaacga ctggtcacgg tggtgaatca aaaagggtat
    10801 cgggtggcgt ctatgtcaga gcaggagctg ctcgatattt tcgacgcccg cgccaatatg
    10861 gaagcgatgc tggtcagtct ggcgattgcc cgcggtggcg atgaatggga ggcagacgtt
    10921 ctcgcaaaag cgcatctgct cagtaagctg gaggcctgtg acgccagtga gaaaatgctt
    10981 gatgagtggg atctgcgtca tcaggcattt catactgcaa ttgtggcagg ctgtggttct
    11041 cactatttgc tgcaaatgcg tgaacggttg tttgatctgg cggcgcgcta tcgatttatc
    11101 tggctgcggc gaacagtgct ttcggtggaa atgctggaag ataaacgcga tcagcaccag
    11161 accctgactg cggcggtact ggcgcgagat accgcgcgcg ccagtgagtt aatgcgccag
    11221 catttactga cgccaattcc cattatccag caggcaatgg ctggcaatta actactcttc
    11281 aggaatacgc aacacttgcc ccgggtaaat tttatccggg cttttgagca tcggtttatt
    11341 cgcttcgaag attttattgt acagattggc gttaccgtag acctgtttgg aaatggcact
    11401 caaagtgtcg ccagacttaa cggtataaaa ctggctggca gtggctggtg tcaccgtttt
    11461 cacctgatca tcgacactgg caataccgga aatatttccc accgcaacaa ggattttctc
    11521 ctttgcctcc tgactcaggc catcacccgt gaccgtcgct ttgccgtcgg cgatttgaat
    11581 gttcacttta tcggcatcag gtataccggt tttgttcaga tgctcctgca ccttcttcgc
    11641 ctgatcgtct ttatcgtgct gacctgtaac cgcgtcccag agtttttctc cggcatcttt
    11701 cacaaaattg aacagaccca tagctacctc attcgttaac ggaaacactc agaaagtgta
    11761 gcagaggaac gcggcgcgtt aacgccgcgg gggtgaacac aggtttaatc gcgggtttgc
    11821 acccagaacg cgtgaatcaa accggggata tacccaagca gtgtcagcag aatattaata
    11881 atgaacgccc aaccgaaccc tttaccgagc agcacgccga gcggcggcag aatgatggtg
    11941 atgacgattc tccagaaacc catatgtact ccctataaga aaattactca ttgtttaaaa
    12001 agagatttta tctcttaagc gtagtaattt tagcggagcc tgccagtttc agcttacgct
    12061 tttactctca tttacgctgc tgatgctggt atatgttgca tttttagttt agagtttact
    12121 taatttagaa aacacttaaa taactatgac tgaactcgcg caattacagg ccagtgccga
    12181 acaggcagcg gccttattga aagcaatgag ccaccctaaa cggttgctga ttctgtgcat
    12241 gcttagcggt tcccccggca cgagcgcggg agagctgacg cgcattaccg gactgagtgc
    12301 ctctgcaaca tcacagcatc tcgctcgtat gcgggacgaa gggcttatcg acagccaacg
    12361 ggatgcccaa cgcattctat attccattaa aaatgaggcg gtaaatgcca ttatcgccac
    12421 ccttaaaaat gtctattgtc cgtaaggagt cactatggct ttgacaacca tttcgccgca
    12481 tgatgcacaa gaattaatcg cacgcggcgc aaagttaatc gatattcgtg acgctgatga
    12541 atatcttcgt gaacatattc ctgaagcaga tctggctcca ttatccgtgc tcgaacagtc
    12601 aggtcttccg gctaaattac gtcgcgagca aattatattc cactgccagg caggtaaacg
    12661 caccagtaat aacgccgata aattagcagc gattgccgcc cccgcagaaa tctttttact
    12721 cgaagatggg attgatggct ggaaaaaagc aggattgcca gtagcggtaa ataaatctca
    12781 acccttgccg ttaatgcgcc aggtgcagat cgccgcaggt ggtttaatat taatcggcgt
    12841 tgtactgggt tataccgtaa atagcggttt cttcttatta agcggctttg ttggtgccgg
    12901 gttactgttt gcaggaatta gcggtttttg tgggatggca aggttgttag ataagatgcc
    12961 ttggaaccaa cgagcttgag aagcgacgcc ggacgcgcca tagcagcgac atccggcctc
    13021 agtaattaga tcaggaaatc gtcgagagat ttaccttctg ccagcgcctg agcgattggc
    13081 ttcggtgtac ggccctgacc ggtccaggtt ttagtttcac cgttaacatc ggtgaattta
    13141 tattttgccg gacgcggctg gcgtttttta ccagcgcgtg gtgcagcagc agagctatta
    13201 cccaataact cttccgggtt aattccgtca gctttcatca gctccagcca ggtactaatt
    13261 ttttcctggc gctctgccag ttcacgctgc tgctgttctt cttcttcacg tctttcttta
    13321 gtgacaaccc tgaatttttc gagcatttct tcaagaacgt caatggagaa ttcgcgagcc
    13381 atcgcacgga gagtgcgaat gttatttaaa ctttgtaaca ttacggacat aataaagaaa
    13441 accttttaac gccaaaacaa aaaagtattt cgtcgcgtag tgtaagcgat cacttattat
    13501 atttccacaa aatttaatct atttacagtc ctgcgcgaga ttatttcagc tgttattttc
    13561 tgaaactctc agaataattt caagattata tattagccat tttgatgagt aatttaggtt
    13621 atttgtgagc agagcggcgc tctctgctcg ctaattccgc aagcctgaca aaaccaaagt
    13681 gaataaaaat gcaactcaac agaataaaag aaaacatcta tcactggtgc tttctgctgt
    13741 caatgtacat tatctggcat aaaaaatgct gaaaatgacc cggtcacgac atacaccgaa
    13801 ttctctacgc ttatagcgtt acctcccccc aaaccttcat gagtgaaaat aaaggtaaac
    13861 acatatccaa ttgatttaat taaaaataaa tcatattggc atgtaaaaat ccacaatgta
    13921 caaaaaacgc gccgttacgg aatattttat ctacaaaaac agattaaata aaaatttttc
    13981 actaattgat tagtcatatc cagcgatata cgctatgcga aaatgcagat ggcaatgaga
    14041 tccactgctt tcatctccat tcacatccca ttacgctttt attaaggagc attagcatgt
    14101 tctcaccgca gtcacgcttg cgtcatgcag ttgcagatac gttcgcgatg gttgtttact
    14161 gttctgtcgt gaacatgtgt attgaagttt tcctctccgg aatgagcttc gaacagtctt
    14221 tttattccag attggtagcg attccggtga acatcttaat tgcatggcca tacggtatgt
    14281 accgcgatct gtttatgcgc gcagcacgca aagttagccc gtcgggctgg ataaaaaatc
    14341 tggcggatat catggcttat gtgacgttcc agtcaccggt gtatgtggcg atcttgttag
    14401 tggtgggcgc agactggcat cagattatgg cggcggtcag ttcaaacatc gttgtttcga
    14461 tgttgatggg ggcggtttat ggctacttcc tcgattattg ccgccgactg tttaaagtca
    14521 gccgttacca gcaggtaaaa gcctgagcct tcttttcgcg actggcatcg ccagtcgcgt
    14581 ctttaactgg cttcgccaaa taaaccattc aaataacgtt caagcgcaac acgcgaacta
    14641 aagccatgcg ggataccgta atgctcatga cgttcacccg ctaaatagag cggaaattgt
    14701 tgataatgat cgcaagtttt aatatcggaa gcgggttcag ccagtgttga actacgttct
    14761 tttaatgttg gatgaatcac cagggcggta cgtcccattc gcgcttcgcg attaacatag
    14821 acataatttt ccccacggcg gtaaccataa gctttctggg ttaccacatc gacagtaaaa
    14881 ccgacttttt caagtacgcg cgccacctcg tctggtcgta aatacatatt tgatcctcgt
    14941 tattatcaac cgcgggccta ccttacctga ttgcgcattc acaacgcttt cagaaaagtc
    15001 cataaagccg cgatgaacct cagttaagaa aattatggtc tacactgaaa attacatcga
    15061 attctaatgg gggatcatat gtttaaccga ccgaaccgca acgacgttga tgatggcgtg
    15121 caggatatcc agaatgatgt caatcaatta gctgacagtc tcgaatctgt attgaagtcc
    15181 tagggcagcg acgccaaagg ggaagccgaa gccgctcgtg gtaaagcgca ggctctactg
    15241 aaagaaacca gggcgcgaat gcatggtcgt actcgcgtcc agcaagccgc gcgcgatgcc
    15301 gttggctgcg cggattcttt tgttcgtgaa agaccctggt gtagcgtggg tacagcagct
    15361 gcggtaggta tttttatcgg cgcactgtta agcatgcgca aatcgtagtg caataatgat
    15421 aataaatacg cgtctttgac cccgaagcct ggcttcgggg tttctttttg cctggtgaat
    15481 cacaaaaatc cccctacccc gtcacgctca tacccagggt aatttcgacc actatttgct
    15541 atatattgtg tggttgaatc ttttttcaac tacatctagt atctctgtat caacagagag
    15601 acaacccgac gcgtatcatc gcgccgtatc ttcattttaa acggaaatac gaatcatgcg
    15661 cattactatt tacactcgta acgattgcgt tcagtgccac gccaccaaac gggcgatgga
    15721 aaaccggggc tttgattttg aaatgattaa tgtcgatcgc gttcctgaag cggcagaagc
    15781 gctgcgtgct cagggctttc gtcagttgcc ggttgtgatt gcaggcgatc ttagctggtc
    15841 tggcttccgc ccggacatga tcaaccgtct gcatccagca ccacacgcgg ccagtgcatg
    15901 agccagctcg tctacttctc cagtagctcc gaaaatacgc agcgttttat cgaacgttta
    15961 ggactgcccg cggtgcgcat cccgctcaat gagcgggaac ggattcaggt agacgagcct
    16021 tacatcctga tcgtgccctc ttacggcggc ggcggtacgg ctggcgcagt gccacgacag
    16081 gtcattcgct ttttaaacaa cgagcacaac cgggtgttgc tgcgcggcgt tattgcttcg
    16141 ggtaatcgca actttggtga ggcgtatggc cgcgccggag atgtgattgc ccggaaatgc
    16201 ggcgtgccgt ggctgtaccg ctttgaactc atgggtacgc aaagcgatat cgaaaacgtt
    16261 cgtaaaggag taaccgaatt ttggcaacga caaccgtaga acgcctgacg caggaaacga
    16321 tggattatca cgctctgaat gcgatgctta acctttacga tagcgcaggt cgcattcagt
    16381 tcgataaaga tcgccaggca gtagacgcct ttataacgac gcatgtgcgt ccgaacagtg
    16441 tggccttcag tagccagcag cagcgcctga actggctggt taacgaaggt tactatgatg
    16501 aaagcgtcct taatcgctac tctcgcgatt ttgtcattac gctgtttgcc cacgcgcacg
    16561 ccagcgggtt tcgtttccag acattcctcg gagcatggaa gttttacacc agctatacgt
    16621 tgaagacatt cgacggtaag cgttatctgg aagattttac cgatcgcgtc acgatggtgg
    16681 cgctgacgct ggcacaaggc gatgaaacac tggcggcgca gctcactgat gagatgctgt
    16741 caggacgctt tcagccagcc acgccgacat tcctcaactg cggtaagcag cagcgcggcg
    16801 aactggtttc ctgttttcta ctgcgtattg aagacaatat ggagtcgatt ggccgggcgg
    16861 taaattccgc actgcaactg tcgaaacgcg gcggcggcgt ggcatttttg ctgtcgaatc
    16921 tgcgggaagc gggcgcgcca attaaacgta ttgaaaatca atcttctggc gtgattccgg
    16981 tgatgaaaat gctggaagac gcattttcct atgccaacca gctcggcgcg cgtcagggtg
    17041 ctggcgcagt ctatttacat gcccatcatc ccgatattct gcgttttctc gatacgaaac
    17101 gggaaaatgc cgacgagaaa atccgcatta aaacactgtc gctgggcgtg gtgatcccgg
    17161 atatcacttt ccatctggca aaagagaatg cgcagatggc actgttttcg ccttatgacg
    17221 ttgagcgggt ttatggcaag ccgtttgctg atatcgccat cagtgaacac tatgccgaac
    17281 tggttgccaa tgaacgcatc cgcaaaaaat acctcaacgc ccgtgatttc ttccagcgac
    17341 tggcagaaat ccagtttgag tccggctatc cctacatcat gtatgaagac acggttaacc
    17401 gtgctaaccc tatcgccggg cgcataaata tgagcaatct ctgctcagaa attttgcagg
    17461 ttaacagcgc ctcagagtat gacgagaatc tcgactatgc ccgcacaggc catgatattt
    17521 cctgcaattt aggttcgttg aatattgccc acaccatgga ttcccccgac tttgcccgca
    17581 cggtagagac tgccgtgcgc ggtttaacgg cagtatcaga tatgagtcat atccgcagcg
    17641 tgccgtccat cgaagccgga aatgccgcct cgcacgccat cggactgggg cagatgaatt
    17701 tacacggtta tctggcgcga gaaggcatcg cttatggatc gccggaagca ctggatttca
    17761 ccaatctcta tttctatacc atcacctggc acgcactgcg tacctcgatg ttgctggcgc
    17821 gcgaacgcag tgaaaccttc gccgggttca aacagtcacg ctatgccaat ggtgaatatt
    17881 tcagccaata tctgcaaggg aactggcagc cgaaaacggc gaaagttggc gaactgtttg
    17941 cccgtagcgg tattacgtta cctacccgtg agatgtgggc gcagctgcgc gacgacgtga
    18001 tgcgctatgg catatacaac cagaatctcc aggcggtgcc gccaacaggt tccatctctt
    18061 atatcaacca tgccacgtcg agtattcatc cgattgtggc gaaagtagag atacgcaaag
    18121 agggcaaaac aggacgcgtt tactaccctg ccccgtttat gactaacgaa aatctggcgc
    18181 tgtatcagga cgcttacgaa atcggcgcag aaaagatcat cgacacctac gcggaagcga
    18241 ctcgccatgt cgatcagggg ctgtcgctga cgctgttttt ccccgatacc gccaccactc
    18301 gcgatatcaa caaagcgcag atttacgcct ggcgcaaggg tatcaaaacg ctctattaca
    18361 tccgcctgcg tcagatggcg ctggaaggca ctgaaattga aggctgcgtc tcgtgtgcac
    18421 tttaaggaat atctatgaaa ctctctcgta tcagcgccat caactggaac aagatatctg
    18481 acgataaaga tctggaggtg tggaatcgcc tgaccagcaa tttctggcta ccagaaaagg
    18541 tgccgctgtc gaacgatatt cctgcatggc agacattaag tgtcgtagaa caacaactga
    18601 cgatgcgcgt ttttactggc ctgacgctgc tcgacacgct gcaaaatgtt atcggcgcgc
    18661 cttcgctgtt gcccgatgca ctcacgcctc atgaagaagc ggtattatcg aatatcagct
    18721 ttatggaagc ggttcatgcc cgctcttaca gttcgatttt ctcgacgctg tgccagacca
    18781 aagatgtcga tgccgcctac gcctggagtg aagaaaacgc accgttgcag cgaaaagctc
    18841 agattattca gcaacattat cgcggggatg atccgctgaa aaagaaaatc gccagtgtgt
    18901 ttcttgaatc ttttttgttc tattccggtt tctggctgcc gatgtatttt tccagccgcg
    18961 gaaagctaac caataccgca gacctgatcc gtctgattat ccgcgatgaa gcagtccacg
    19021 gttattacat cggctataaa tatcagaaaa acatggaaaa gatctcccag gcacaacgtg
    19081 aagagttgaa gagtttcgcc ttcgatttgt tgctggaact ttatgacaac gagttgcaat
    19141 acaccgatga gctgtacgcc gaaaccccgt gggctgacga tgtgaaagcg tttctctgtt
    19201 acaacgccaa taaggcgttg atgaatctgg gctacgaacc gttatttccc gcagaaatgg
    19261 cggaagtgaa tccggcaatc ctcgccgcgc tttcgccgaa tgccgatgaa aatcacgatt
    19321 tcttttccgg ttcaggctct tcatatgtga tgggaaaagc ggtcgaaaca gaagatgaag
    19381 actggaattt ctgagggtgt tatttttcaa aaatatcact acccgcagca gggaaataat
    19441 tcccgccaaa tagcttttta tcacgcaaat aatttgtggt gatctacact gacactctgt
    19501 tgcattattc gcctgaaacc acaatattca ggcgtttttt cgctatcttt gacaaaaaat
    19561 atcaactttt ctcgatttgc tctcagccct tatatcatgg gaaattccgg cgatttgctc
    19621 acatcaatat tcatgccaca tttgccatca ggggttgcct cagattctca gtatgttagg
    19681 gtagaaaaaa gtgactattt ccattgggta atgtatcgac ataaacaaat aacaggaatc
    19741 tttctattgc atggcaatta aattagaaat taaaaatctt tataaaatat ttggtgagca
    19801 tccacagcga gctttcaaat atatcgaaca aggactttca aaagaacaaa ttctggaaaa
    19861 aactgggcta tcgcttggcg taaaagacgc cagtctggcc attgaagaag gcgagatatt
    19921 tgtcatcatg ggattatccg gttcgggtaa atccacaatg gtacgccttc tcaatcgcct
    19981 gattgaaccc acccgcgggc aagtgctgat tgatggtgtg gatattgcca aaatatccga
    20041 cgccgaactc cgtgaggtgc gcagaaaaaa gattgcgatg gtcttccagt cctttgcctt
    20101 aatgccgcat atgaccgtgc tggacaatac tgcattcggt atggaattgg ccggaattaa
    20161 tgccgaagaa cgccgggaaa aagcccttga tgcactgcgt caggtcgggc tggaaaatta
    20221 tgcccacagc tacccggatg aactctctgg cgggatgcgt caacgtgtgg gattagcccg
    20281 cgcgttagcg attaatccgg atatattatt aatggacgaa gccttctcag cactcgatcc
    20341 attaattcgc accgagatgc aggatgagct ggtaaaatta caggcgaaac atcagcgcac
    20401 cattgtcttt atttcccacg atctcgatga agctatgcgt attggcgacc gaattgccat
    20461 tatgcaaaat ggtgaagtgg tacaggtcgg cacaccggat gaaattctca ataatccggc
    20521 gaatgattat gtccgtacct tcttccgtgg cgtcgatatt agtcaggtat tcagtgcgaa
    20581 agatattgct cgccggacac cgaacggctt aatccgtaaa acccccggct tcggcccgcg
    20641 ttcggcactg aaattattgc aggatgaaga tcgcgaatat ggctacgtca tcgaacgcgg
    20701 taataagttt gtcggcgcag tgtctatcga ttcgcttaaa accgcgttaa cgcagcagca
    20761 aggtcttgat gcggcgctga ttgatgcgcc attagcggtc gatgcgcaaa cgcctcttag
    20821 cgagttgctc tctcatgtcg gacaggctcc ctgtgcggtg cccgtggtcg acgaggacca
    20881 acagtatgtc ggcatcattt cgaaaggaat gctgctgcgc gctttagatc gtgagggggt
    20941 aaataatggc tgatcaaaat aatccgtggg ataccacgcc agcggcggac agtgccgcac
    21001 agtccgcaga cgcctggggt acaccggctg ctgcaccgac tgacggcggt ggtgctgact
    21061 ggctgaccag tacgcctgcg ccaaacgtcg agcattttaa tattctcgat ccgttccata
    21121 aaacgctgat cccgctcgac agttgggtca ctgaagggat cgactgggtc gttacccatt
    21181 tccgtcccgt cttccagggc gtgcgcgttc cggttgatta tatcctcaac ggtttccagc
    21241 aattgctgct gggtatgccc gctccggtgg cgattatcgt tttcgctctc atcgcctggc
    21301 aaatttccgg tgtcggaatg ggcgtggcga cgctggtttc gctgattgcc atcggcgcaa
    21361 tcggtgcctg gtcacaggca atggttactc tggcgctggt gctaaccgcc ctgctgttct
    21421 gtatcgtcat cggtttgccg ttggggatct ggctggcgag aagtccacga gcggcgaaaa
    21481 ttattcgtcc actgcttgat gccatgcaga ccacgccagc gtttgtttat ctggtaccaa
    21541 tcgtcatgct gtttggtatc ggtaacgtgc cgggcgtagt ggtgacgatc atctttgctc
    21601 tgccgccgat tatccgtctg acaattctgg ggattaacca ggttccggcg gatctgattg
    21661 aagcctcgcg ctcattcggt gccagcccgc gccagatgct gttcaaagtt cagttaccgc
    21721 tggcgatgcc gaccattatg gcgggcgtta accagacgct gatgctggcc ctttctatgg
    21781 tggtcatcgc ctcgatgatt gcagtcggcg ggctgggtca gatggtactt cgcggtatcg
    21841 gtcgtctgga tatggggctt gccaccgttg gcggcgtcgg gattgtgatc ctcgccatta
    21901 tcctcgaccg cctgacgcag gccgttgggc gcgactcacg cagtcgcggc aaccgtcgct
    21961 ggtacaccac tggccctgtt ggtttgctga cccgcccatt cattaagtaa ctctgcactt
    22021 gcccggtgac gccgggcatt atcaccctgc caaaaaaagg aataacaatg cgacatagcg
    22081 tactttttgc gacagcgttt gccacgctta tctctacaca aacttttgct gccgatctgc
    22141 cgggcaaagg cattactgtt aatccagttc agagcaccat cactgaagaa accttccaga
    22201 cgctgctggt cagtcgtgca ctggagaaat taggttatac cgtcaataaa cccagcgaag
    22261 tggattacaa cgttggctac acctcgcttg cttccggcga tgcaaccttc accgccgtga
    22321 actggacgcc gctgcatgac aacatgtacg aagctgccgg tggcgataag aaattttatc
    22381 gtgaaggagt atttgttaac ggcgcggcac agggttacct gatcgataag aaaactgccg
    22441 accagtacaa aatcaccaac atcgcgcaac tgaaagatcc gaagatcgcc aaactgttcg
    22501 ataccaacgg cgacggtaaa gcggatttga ctggctgtaa ccctggctgg ggctgcgaag
    22561 gtgcgatcaa ccaccagctt gccgcgtatg gactgaccaa taccgtgacg cataatcagg
    22621 ggaactacgc agcgatgatg gctgacacca tcagtcgtta caaagagggt aagccggtgt
    22681 tttactacac ctggacgccg tactgggtga gtaacgaact gaaaccgggg aaagatgtgg
    22741 tctggttgca ggtgccgttc tccgcactgc cgggcgataa aaatgccgat accaaactgc
    22801 cgaatggcgc gaattacggc ttcccggtca gtaccatgca tatcgttgcc aacaaagcct
    22861 gggccgagaa aaacccggca gcagcgaaac tgtttgccat tatgcagtta ccagtggcag
    22921 atattaacgc ccagaacgcc attatgcatg acggcaaagc ctcagaaggc gatattcagg
    22981 gccacgttga tggctggatc aaagcccacc agcagcagtt cgatggctgg gtgaatgagg
    23041 cgctggcagc gcagaagtaa atattgataa ccgcgcagat aatgctcatg tgagtaaaac
    23101 aattgcagcg atggttttaa tccggctgaa aatcgatgag acgttttctg aaggccgggg
    23161 cgacgcgcag ggatgcgcgg cgagggcgcg tcttacaggg atgttacctc gcgcccgtac
    23221 ccgatagccg taagaaataa gtcgaatgta ccgcgtagcg gcgattttgt gccaaaagtt
    23281 tgggtcgcca gggtggtggc gactgagcca ccctggcacg ttcaccagca aaatagtgac
    23341 aaagtagcta taatctggaa gtgaacgtaa catttgcctt agtggcatat ttcaccttca
    23401 aataccctct ccccattacc cgcacatttt aacaatctat ctttcgcccc atattcatca
    23461 acatccgcta ttattgattt ccagcttaat catcacctga tgaacaaaaa taatgactaa
    23521 acctaatcat gagcttagcc cggcactgat cgtactgatg tctatcgcca ccggtctggc
    23581 ggtcgccagc aactattacg cccagccatt gctcgacacc attgcgcgta acttttccct
    23641 ttccgccagt tcggcgggct ttattgttac cgccgcgcag ttgggctatg ccgcaggtct
    23701 gctgtttctt gttcccctcg gtgatatgtt tgaacgccgc cgcctgattg tctcgatgac
    23761 cttactggca gcgggcggta tgttaatcac tgccagcagt cagtcactgg cgatgatgat
    23821 cctcggtacg gcattaaccg gtttattctc agtcgtggca caaattctgg ttccgctggc
    23881 agcgacgctg gcttcaccgg ataaacgcgg caaagtggtc ggcaccatta tgagcgggct
    23941 gctgttgggg atcttgctgg cacgaaccgt tgccgggttg ctggcaaacc tcggcggctg
    24001 gcgcaccgtc ttttgggttg cctcggtgtt aatggcactg atggcgctgg cattatggcg
    24061 tggtctgcca caaatgaaat cagaaaccca cctcaactac ccacagttgt tgggttccgt
    24121 tttcagcatg tttatcagcg ataagatcct gcgcacccgt gcgttgctgg gctgcctgac
    24181 ctttgccaac ttcagcattc tctggacctc aatggccttt ttgcttgccg ctccaccttt
    24241 taactacagc gatggtgtaa ttggtctgtt tggacttgcg ggagctgccg gagcgttggg
    24301 tgctcgtccg gcgggcggtt ttgccgataa gggtaaatcg caccacacca ctactttcgg
    24361 tctgctgctg ctattacttt catggctggc gatctggttt ggccacactt ccgtactggc
    24421 cttgattatc ggcatcctgg tgctggatct caccgtgcag ggcgtgcata tcactaacca
    24481 gacggtaatt tatcgaatac accctgatgc gcgtaatcgc ctgaccgcag gttacatgac
    24541 cagctacttt attggcggtg ccgccggttc gctaatttca gcctcagcct ggcaacatgg
    24601 cggttgggct ggcgtttgtc tggctggcgc gacgattgcc ctggttaact tactggtctg
    24661 gtggcgaggt tttcatcgtc aggaagccgc aaattaagca atcagcaacc gttttcgtgg
    24721 ctttacactt ataagggtgt taagaagccc atcagtctga taaggttaag atattcattc
    24781 agtctattta taatattaac aatcgttaag cgtacactct atggaaagcc ctactccaca
    24841 gcctgctcct ggttcggcga ccttcatgga aggatgcaaa gacagtttac cgattgttat
    24901 tagttatatt ccggtggcct ttgcgttcgg tctgaatgcg acccgtctgg gattctctcc
    24961 tctcgaaagc gtttttttct cctgcatcat ttatgcaggc gcgagccagt tcgtcattac
    25021 cgcgatgctg gcagccggga gtagtttgtg ggttgctgca ctgaccgtca tggcaatgga
    25081 tgttcgccat gttttgtatg gcccgtcact gcgtagccgt attattcagc gtctgcaaaa
    25141 atcgaaaacc gccctgtggg catttggcct gacggatgag gtttttgccg ccgcaaccgc
    25201 aaaactggta cgcaataatc gccgctggag cgagaactgg atgatcggca ttgccttcag
    25261 ttcatggtca tcgtgggtat ttggtacggt aataggggca ttctccggca gcggcttgct
    25321 gcaaggatat cccgccgttg aagcagcatt aggttttatg cttccggcac tctttatgag
    25381 tttcctgctc gcctctttcc agcgcaaaca atctctttgc gttaccgcag cgttagttgg
    25441 tgcccttgca ggcgtaacgc tattttctat tcccgtcgcc attctggcag gcattgtctg
    25501 tggctgcctc actgcgttaa tccaggcatt ctggcaagga gcgcccgatg agctatgagg
    25561 ttctgctgct tgggttactg gttggcgcgg cgaattattg cttccgctat ttgccgctgc
    25621 gcctgcgtgt gggtaatgcc cgcccaacca aacgtggcgc gataggcata ttgctcgaca
    25681 ccattggcat cgcctcgata tgcgctctgc tggttgtctc taccgcacca gaagtgatgc
    25741 acgatacacg ccgtttcgtg cccacgctgg tcggcttcgc ggtactgggt gccagtttct
    25801 ataaaacacg cagcattatc atcccaacac tgcttagtgc gctggcctac gggctcgcct
    25861 ggaaagtgat ggcgattata taacccacaa gaatcatttt tctaaaacaa tacatttact
    25921 ttatttgtca ctgtcgttac tatatcggct gaaattaatg aggtcatacc caaatggata
    25981 gttcgtttac gcccattgaa caaatgctaa aatttcgcgc cagccgccac gaagattttc
    26041 cttatcagga gatccttctg acccgtcttt gcatgcacat gcaaagcaag ctgctggaga
    26101 accgcaataa aatgctgaag gctcagggga ttaacgagac gttgtttatg gcgttgatta
    26161 cgctggagtc tcaggaaaac cacagtattc agccttctga attgagttgt gctcttggat
    26221 catcccgtac caacgcgacg cgtattgccg atgaactgga aaaacgcggt tggattgaac
    26281 gtcgtgaaag cgataacgat cgccgctgcc tgcatctgca attaacggaa aaaggtcacg
    26341 agtttttgcg cgaggtttta ccaccgcagc ataactgcct gcatcaactc tggtccgcgc
    26401 tcagcacaac agaaaaagat cagctcgagc aaatcacccg caaattgctc tcccgtctcg
    26461 accagatgga acaagacggt gtggttctcg aagcgatgag ctaacgcgtc atctcgctca
    26521 aaaatccaga tttataaaag aaaaaatgac tggccagcat cgcaacatgc tggccttttt
    26581 ggcaagcagg tcggctcagc cgatgagtta agaagatcgt ggagaacaat atgagcgcaa
    26641 atgcggagac tcaaaccccg cagcaaccgg taaagaagag cggcaaacgt aagcgtctgc
    26701 tcctccttct caccttgctc tttataatta ttgccgtagc gatagggatt tattggtttt
    26761 tggtactgcg tcatttcgaa gaaaccgatg acgcatacgt ggcagggaat cagattcaaa
    26821 ctatgtctca ggtgtctggc agcgtgacga aagtctgggc cgataacacc gactttgtaa
    26881 aagaaggcga tgtgctggtc accctcgacc cgacagatgc tcgccaggcg tttgaaaaag
    26941 ccaaaactgc actggcttcc agcgttcgcc aaacccacca gctgatgatt aacagcaaac
    27001 agttgcaggc gaatattgag gtgcaaaaaa tcgcactcgc gaaagcacaa agcgactaca
    27061 accgccgtgt gccgctgggc aatgccaacc tgattggtcg cgaagagctg caacacgccc
    27121 gcgacgccgt taccagtgcc caggcacaac tggacgtcgc gattcaacaa tacaatgcca
    27181 atcaggcgat gattctgggg actaaactgg aagatcagcc tgccgtgcaa caggctgcca
    27241 ccgaagtacg taacgcctgg ctggcgctgg agcgtactcg tattgtcagt ccgatgaccg
    27301 gttatgtctc ccgccgcgcg gtacagcctg gggcacaaat tagcccaacg acgccgctga
    27361 tggcggtcgt tccagccacc aatatgtggg tggatgccaa ctttaaagag acgcagattg
    27421 ccaatatgcg catcggtcag ccggtcacca tcaccaccga tatttacggc gatgatgtga
    27481 aatacaccgg taaagtggtt ggtctggata tggggacagg tagcgcgttc tcactgcttc
    27541 cggcgcaaaa tgcgactggt aactggatca aagtcgttca gcgtctgcct gttcgtattg
    27601 aactggacca gaaacagctc gagcaatacc cgctgcgtat cggtttgtcc acgctggtga
    27661 gcgtcaatac cactaaccgt gacggtcagg tactggcaaa taaagtacgt tccacaccgg
    27721 tagcggtaag caccgcgcgt gaaatcagcc tggcacctgt caataaactg atcgacgata
    27781 tcgtaaaagc taacgctggc taatccagag gtgcgtgtga tgcaacagca aaaaccgctg
    27841 gaaggcgcgc aactggtcat tatgacgatt gcgctgtcac tggcgacatt catgcaggtg
    27901 ctggactcca ccattgctaa cgtggcgatc cccactatcg ccgggaatct gggctcatcg
    27961 ctcagccagg gaacgtgggt aatcacttct ttcggggtgg cgaatgccat ctcgatcccg
    28021 cttaccggct ggctggcaaa gcgcgtcggg gaagtgaaac tgttcctctg gtcaaccatc
    28081 gcctttgcta ttgcgtcgtg ggcgtgtggt gtctccagca gcctgaatat gctgatcttc
    28141 ttccgcgtga ttcaggggat tgtcgccgga ccgttgatcc cgctttcgca aagtctattg
    28201 ctgaataact acccgccagc caaacgctcg atcgcgctgg cgttgtggtc aatgacggtg
    28261 attgtcgcgc caatttgcgg cccgatcctc ggcggttata tcagcgataa ttaccactgg
    28321 ggctggatat tcttcatcaa cgtgccaatt ggcgtggcgg tggtgttgat gacactgcaa
    28381 accctgcgcg gacgcgaaac ccgcaccgaa cggcggcgga ttgatgccgt ggggctggca
    28441 ctgctggtta ttggtatagg cagcctgcag attatgctcg accgcggtaa agagctggac
    28501 tggttctcat cacaggaaat tatcatcctt accgtggtgg cagtggtggc tatctgcttc
    28561 ctgattgtct gggagctgac cgacgataac ccgatagtcg atctgtcgtt gtttaagtcg
    28621 cgcaacttca ccatcggctg cttgtgtatc agcctcgcgt atatgctcta cttcggcgcg
    28681 attgttctgc tgccgcagtt gttgcaggag gtctacggtt acacggcaac gtgggcaggt
    28741 ctagcctctg cgccggtagg aattattccg gtgatcctgt cgccgattat cggccgcttc
    28801 gcgcataaac tggatatgcg gcggctggta accttcagct ttattatgta tgccgtctgc
    28861 ttctactggc gtgcctatac ctttgaacca ggtatggatt ttggcgcgtc ggcctggccg
    28921 cagtttatcc agggttttgc ggtggcctgc ttctttatgc cgctgaccac cattacgctg
    28981 tctggtttgc caccggaacg actggcggca gcatcgagcc tctccaactt tacgcgaacg
    29041 ctggcggggt ctatcggcac gtcgataacc acaaccatgt ggaccaaccg cgagtcgatg
    29101 caccatgcgc agttgactga gtcggtaaac ccgttcaacc cgaatgccca ggcgatgtac
    29161 agtcaactgg aagggcttgg gatgacgcaa cagcaggcat caggctggat tgcccagcag
    29221 atcaccaatc aggggctgat tatttccgcc aatgagatct tctggatgtc agccgggata
    29281 ttcctcgtct tgctggggct ggtgtggttt gctaaaccgc catttggcgc aggtggcggc
    29341 ggaggtggtg cgcactaagt acaactaagc cagttcattt gaactggctt ttttcaatta
    29401 attgtgaaga tagtttactg actagatgtg cagttcctgc aacttctctt tcggcagcgc
    29461 cagttcttcg ttgctgttga tgcgtacgtc acgttccaga atgctacgcg caatatcctg
    29521 tgcttcctgc aacgagtgca tctggtaagt gccacactgg tagacgttca gttccgggat
    29581 ctgattctga tcctgcactt tcagcacgtc ttccattgcc gctttccagg catcagcgac
    29641 acgctgctca tctggcgtac caatcagact catataaaaa ccggtgcggc agcccattgg
    29701 cgagatatcg ataatctcta caccattacc gttaagatgg ttacgcataa aaccagcaaa
    29761 caggtgctcc agggtatgga tccctctttc tggcatcact tctttgttcg gcacgcagaa
    29821 gcgcagatcg aacacggtga ttgcgtcgcc atgcggggtg ttcattgttt tcgccacccg
    29881 aactgcaggc gcttccatcc gggtatgatc gactgtgaag ctatctaaca acggcattta
    29941 gccacctccg gtaatttttt taaaaatttt ctgaactctt tcttcccagg cgagtctgag
    30001 tatatgaaag acgcgcattt gttatcatca tccctgaatt cagagatgaa attttggcca
    30061 ctcacgagtg gcctttttct tttctgtcag gcgtgttttt ccagccacac cgcaaacggt
    30121 tcggtatcag cggcttccat ttcctgctga cggcgttcag acgcctcgcg ctcggctaca
    30181 aaatcctctt cgcgcagaat ttccaacggc tcttcacgca gcagattacg gtacgcttca
    30241 gcaaacgctt tgcctgttcc gccaatacca gtatcaatca tagaccttaa gatacgggca
    30301 gagaaagtca gatcgggatt atcgaagcag gcgaccagtt catcacacac tttctgatac
    30361 gcttcgccgc cgttaatgct atccagcgtt tgcgcaacgc gtttcagatc gcggaacaga
    30421 tctttaccca cctgcggtaa cgggaactgc gcggtttcgc agccgatacc cagcgtcagg
    30481 cccggtttgc gaccttcgag gatcacccgg ttccagttaa cgcgtgtaca ggcaagttcg
    30541 cgactgctca tttccggtgc atcagccagc gcacaccaga ccataaacag gtcgaggaat
    30601 cgcacctgct gttcatctac accaatcggc gagaatgggt tgatgtccag cgaacgcact
    30661 tcaatatatt caatgccgcc acgtaacagc gcatcagaag gcgactcacc actgcgggta
    30721 acgcgttttg gacgaatcgg cgcgtacagt tcgttttcaa tctgcagcac attgctgttg
    30781 atttgcagcc gcttaccgtc tttctcaata ccaatcttcg cgtactcttc cgatggcgtt
    30841 ttgattgcct gtttaaggcc cgctacgtac tcgtaaagat cgttgaaggt aataccaaga
    30901 ttgctttgcg atttgttggt atagccaaga tcgctcaaac gaagagaggt cgcatacggc
    30961 aggtaataca taccgcactc ggttttctca aacggcagcg acgttggttt tccttgcagg
    31021 aaagaagaac aaatcgccgg agacgcgcca aacagataag gaatgaccca accgaaacga
    31081 tagtaattgc ggataacgcg gaaatagccc gcagaaattt tctctttggc atcagcgccc
    31141 gcgatatcac cacacttcgc ttgccagaat gccattggca aagagaaatt gtagtgcacg
    31201 ccggaaatgg tttgcatcag cgcgccgtag cgatttttca gcccttcacg gtacagcgtt
    31261 ttaaagcgtc cggtgttaga agtgccgtac tgtgccagtt cgatgtcctg accttctgcg
    31321 atgtagcatg gcatacttaa cggccacatc cgctcatcgc ccatattgcg cgccgtataa
    31381 cgatgcagat cgcgcataaa ggtcagcata tgttcaatat caccatccac tggtgtaatg
    31441 aattccagta atgcttccgc aaaatcggta gtaatccatt tgtgcgtcag tgcggaacct
    31501 aatgcttcag gatgacctgt tgttgccagt ctgccatcag cattaacacg caaagtttcg
    31561 cgctccagcc cacgctgtat cccctttaac gcctgaggat gtttttccag ccaggccagc
    31621 gcctgtgata cgtccgggat caaattgacc tcccgcctgt caaaatcgtt ttaattagca
    31681 taactgtaat ggtgaccata tgtgcaggcc tacaattagt gccaccacat catgccctga
    31741 acggtcgctg ctgcaactgc aacatagcgt aacgctttac caaggcacaa aaaaaagatt
    31801 accggccccc aggagatgcg catccatccc gctaacagac acagtaaatc gccaaccacg
    31861 ggcatccagc ttaataatag cgtgactgca ccatagcgtt tcagccagcc ggtagctttc
    31921 tcttgccagc gcgatgtttt acgcaatgga aagaaacgcc caaggataac gttagttaac
    31981 cctccaaggc tattacccat tgttgctgtt aaaactaaaa cccagggatg actgatcccg
    32041 gaaagcaaca ttgccaccag cacgacttcg gagttgccgg gtaatagtgt agcgctgaga
    32101 aaactactgg caaacaacga gaaaagcgat aacgcttcac tcacagcaag cgaacatcca
    32161 cagcgtccat gcctgctgca cgggccgcca gaataccgaa atcggcatct tcaaagacca
    32221 cacactgtgt cggttgcacg cccatacgct gcgcgcacaa caaaaatgtg tctggcgcgg
    32281 gtttatggtg tttgacgtga tcagcagcga cgacggcgtc aaaataacgg cgtaatccca
    32341 ggtgcgccag caatgcctca gcgatggcgc tttcactccc cgttcctaca gccattgggc
    32401 gacgaccatg ccagcttttc accacttcaa caagaggaag cggctcgaca ctatccagca
    32461 gcatacttct tactgcttct gttttttcac gcgctaacgc atgcgggtcg agatcggcct
    32521 gattcagctc aataatcgcc tgagcaatac gccaggtggg cgagccatta agcgcaatca
    32581 tcgcctgaac atcgtactga agaccgtagt gccctaatac ttcgcgccac gctttacggt
    32641 gcgtaggctc ggtatccagg atggtgccat ccatatcaaa aattaaacct gcataacgct
    32701 cgtacatggt cttctcgcaa gtcgaaaaat atgacgctac tttagcgtaa ttgcttgatt
    32761 ttgtcgctga tggcgaagga gaagaaaatt caggaaatgg ataaagtagt tatttagaaa
    32821 tgagatattt ttgaaggaaa tttgtgggag aagatggtgc ctgcggttag taccgctacc
    32881 tcttcgatac cttcattgct gaagattacg gagaatatgg tgcatccggg aggattcgaa
    32941 cctccgaccg ctcggttcgt agccgagtac tctatccagc tgagctacgg atgcatcggg
    33001 aaaacttatt ttactgctga tattgatacc gctactaaag c
//
LOCUS       DACAOP010000045        33033 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.045, whole genome shotgun sequence.
ACCESSION   DACAOP010000045 DACAOP010000000
VERSION     DACAOP010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33033
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.045"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            16..684
                     /locus_tag="IT892_002393"
                     /pseudo
     CDS             16..684
                     /locus_tag="IT892_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151635.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
     gene            835..1344
                     /locus_tag="IT892_002394"
     CDS             835..1344
                     /locus_tag="IT892_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HAP3135602.1"
                     /translation="MNLQRFDDSTLIRIFALHELHRLKEHGLTRGALLDYHSRYKLVF
                     LAHSQPEYRKLGPFVADIHQWQNLDDYYNQYRQRVVVLLSHPANPRDHTNVLMHVQGY
                     FRPHIDSTERQQLAALIDSYRRGEQPLLAPLMRIKHYMALYPDAWLSGQRYFELWPRV
                     INLRHSGVL"
     gene            1341..2759
                     /gene="phrB"
                     /locus_tag="IT892_002395"
     CDS             1341..2759
                     /gene="phrB"
                     /locus_tag="IT892_002395"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HAP3135603.1"
                     /translation="MTTHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWAT
                     HNMSPRQAELINAQLNGLQIALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFY
                     NYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLK
                     RLREGMPECVAAPKVRSSGSIEPSPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQN
                     GAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLNEL
                     IWREFYRHLITYHPSLCKHRPFIAWTDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQL
                     NSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTD
                     AAPYFRIFNPTTQGEKFDHEGEFIRQWLPELRDVPGKVVHEPWKWAQKAGVTLDYPQP
                     IVEHKEARVQTLAAYEAARKGK"
     gene            complement(2909..4390)
                     /gene="dtpD"
                     /locus_tag="IT892_002396"
     CDS             complement(2909..4390)
                     /gene="dtpD"
                     /locus_tag="IT892_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide permease DtpD"
                     /protein_id="HAP3135604.1"
                     /translation="MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYND
                     THAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSF
                     LYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGY
                     AQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLV
                     LLVATPALITILFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFF
                     SMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKE
                     SVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAEL
                     FIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINY
                     SINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES"
     gene            4661..5404
                     /gene="ybgI"
                     /locus_tag="IT892_002397"
     CDS             4661..5404
                     /gene="ybgI"
                     /locus_tag="IT892_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radiation resistance protein YbgI"
                     /protein_id="HAP3135605.1"
                     /translation="MKNTELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTA
                     SQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDA
                     HPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDT
                     GPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHAT
                     ERGGIRALSEWLNENTDLDVTFIDIPNPA"
     gene            5427..6083
                     /gene="pxpB"
                     /locus_tag="IT892_002398"
     CDS             5427..6083
                     /gene="pxpB"
                     /locus_tag="IT892_002398"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HAP3135606.1"
                     /translation="MQRARCYLIGETAVVLELEPPVTLASQKRIWRLAQRLVDMPNVV
                     EAIPGMNNITVILRNPESLALDAIERLQRWWEESEALEPESRFIEIPVVYGGAGGPDL
                     AVVAAHCGLSEKQVVELHSSVEYVVWFLGFQPGFPYLGSLPEQLHTPRRAEPRLLVPA
                     GSVGIGGPQTGVYPLATPGGWQLIGHTSLSLFDPARDEPILLRPGDSVRFVPQKEGVC
                     "
     gene            6077..7009
                     /gene="pxpC"
                     /locus_tag="IT892_002399"
     CDS             6077..7009
                     /gene="pxpC"
                     /locus_tag="IT892_002399"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpC"
                     /protein_id="HAP3135607.1"
                     /translation="MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLV
                     GNDANAPALEITLGQLTVEFETDGWFALTGAGCEARLDDNAVWTGWRLPMKAGQRLTL
                     KRPQHGMRSYLAVAGGIDVPPVMGSCSTDLKVGIGGLEGRLLKDGDRLPIGKSKRDSM
                     EAQGVKQLLWGNRIRALPGPEYHEFDRASQDAFWRSPWQLSSQSNRMGYRLQGQILKR
                     TTDRELLSHGLLPGVVQVPHNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQ
                     PIHFVQCSLEEALKARQDQQRYFEQLAWRLHNEN"
     gene            6999..7733
                     /gene="pxpA"
                     /locus_tag="IT892_002400"
     CDS             6999..7733
                     /gene="pxpA"
                     /locus_tag="IT892_002400"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HAP3135608.1"
                     /translation="MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQIMQACV
                     REAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRH
                     VKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGKQYGLTTREEVF
                     ADRGYQADGSLVPRSQSGALIENEEQALAQTLEMVQHGRVKSITGEWATVAAQTVCLH
                     GDGEHALAFARRLRSAFAEKGIVVAA"
     gene            7769..8560
                     /gene="nei"
                     /locus_tag="IT892_002401"
     CDS             7769..8560
                     /gene="nei"
                     /locus_tag="IT892_002401"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease VIII"
                     /protein_id="HAP3135609.1"
                     /translation="MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKPYQSQLIGQH
                     VTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTIL
                     LYSASDIEMLTPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLD
                     QAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLEIPRFSYATRGQVDE
                     NKHHGALFRFKVFHRDGEPCERCGSIIEKTTLSSRPFYWCPGCQH"
     gene            complement(8557..9603)
                     /locus_tag="IT892_002402"
     CDS             complement(8557..9603)
                     /locus_tag="IT892_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415243.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP3135610.1"
                     /translation="MPVLQWGMLCVLSLLLSIGFLAVHLPAALLLGPMIAGIIFSMRG
                     ITLQLPRSAFLAAQAILGCMIAQNLTGSILTTLAVNWPIVLAILLVTLLSSAIVGWLL
                     VRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRM
                     MLGDNAEAVNQHIVWFPPVSINLLLTILLAVVAGTVGCLLRLPSGTMLIPMLAGAVLQ
                     SGQLITIELPEWLLAMAYMAIGWRIGLGFDKQILLRALRPLPQILLSIFALLAICAGM
                     AWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIMAMQTLRLFSILLTGPA
                     IARFISTYAPKRSA"
     gene            complement(9755..10816)
                     /locus_tag="IT892_002403"
     CDS             complement(9755..10816)
                     /locus_tag="IT892_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415244.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3135611.1"
                     /translation="MSAGKGLLLVICLLFLPLKSAMALNCYFGTSGGAVEKSEAIQPF
                     AVPGNAKPGDKIWESDDIKIPVYCDNNTNGNFESEHVYAWVNPYPGVQDRYYQLGVTY
                     NGVDYDASLGKSRIDTNQCIDSKNIDIYTPEQIIAMGWQNKICSGDPANIHMSRTFLA
                     RMRLYVKIREMPPHDYQSTLSDYIVVQFDGAGSVNEDPTAQNLKYHITGLENIRVLDC
                     SVNFSISPETQVIDFGKFNLLDIRRHTMSKTFSIKTTKSQNDQCTDGFKVSSSFYTEE
                     TLVEEDKALLIGNGLKLRLLDENASPYTFNKYAEYADFTSDMLVYEKTYTAELSSIPG
                     TPIEAGPFDTVVLFKINYN"
     gene            complement(10813..11541)
                     /locus_tag="IT892_002404"
     CDS             complement(10813..11541)
                     /locus_tag="IT892_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HAP3135612.1"
                     /translation="MTFIKGLPLMLLTISLGCNAAVQPDRTRIVFNANDKATSLRIEN
                     QSDKLPYLAYSWIENEKGEKSDALLVALPPIQRLEPKATSQVRVVKQASTTQLPGDRE
                     TLFFYNMREIPPAPDKSSDHAILQVAIQSRIKLFWRPAALRKKAGEKVELQLQVSQQG
                     NQLTLKNPTAYYLTIAYLGRNEKGVLPGFKTVMVAPFSTVNTNTGSYSGSQFYLGYMD
                     DYGALRMTTLNCSGQCRLQAVEAK"
     gene            complement(11556..14012)
                     /locus_tag="IT892_002405"
     CDS             complement(11556..14012)
                     /locus_tag="IT892_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706516.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HAP3135613.1"
                     /translation="MDTVNIYRLSFVSCLVMAMPCAMAVEFNLNVLDKSMRDRIDISL
                     LKEKGVIAPGEYFVSVAVNNNKISNGQKINWQKKGDKTIPCINDSLVDKFGLKPDIRQ
                     SLPQIDRCIDFSSRPEMLFNFDQANQQLNISIPQAWLAWHSENWAPPSTWKEGVAGVL
                     MDYNLFASSYRPQDGSSSTNLNAYGTAGINAGAWRLRSDYQLNKTDSEDNHDQSGGIS
                     RTYLFRPLPQLGSKLTLGETDFSSNIFDGFSYTGAALASDDRMLPWELRGYAPQISGI
                     AQTNATVTISQSGRVIYQKKVPPGPFIIDDLNQSVQGTLDVKVTEEDGRVNNFQVSAA
                     STPFLTRQGQVRYKLAAGQPRPSMSHQTENETFFSNEVSWGMLSNTSLYGGLLISDDD
                     YHSAAMGIGQNMLWLGALSFDVTWASSHFDTQQDERGLSYRFNYSKQVDATNSTISLA
                     AYRFSDRHFHSYANYLDHKYNDSDAQDEKQTISLSVGQPITPLNLNLYANLLHQTWWN
                     ADASTTANITAGFNVDIGDWRDISISTSFNTTHYEDKDRDNQIYLSISLPFGNGGRVG
                     YDMQNSSHSTIHRMSWNDTLDERNSWGMSAGLQSDRPDNGAQVSGNYQHLSSAGEWDI
                     SGTYAASDYSSVSSSWSGSFTATQYGAAFHRRSSTNEPRLMVSTDGVADIPVQGNLDY
                     TNHFGIAVVPLISSYQPSTVAVNMNDLPDGVTVAENVIKETWIEGAIGYKSLASRSGK
                     DVNVIIRNASGQFPPLGADIRQDDSGISVGMVGEEGHAWLSGVAENQLFTVVWGEQSC
                     IIHLPERLEDTTKRLILPCH"
     gene            complement(14063..14629)
                     /locus_tag="IT892_002406"
     CDS             complement(14063..14629)
                     /locus_tag="IT892_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HAP3135614.1"
                     /translation="MFKGQKTLAALAVSLLFTAPVYAADEGSGEIHFKGEVIEAPCEI
                     HPEDIDKNIDLGQVTTTHINREHHSNKVAVDIRLINCDLPASDNGSGMPVSKVGVTFD
                     STAKTTGATPLLSNTSAGEATGVGVRLMDKNDGNIVLGSAAPDLDLDASSSEQTLNFF
                     AWMEQIDNAVDVTAGEVTANATYVLDYK"
     gene            complement(15019..16302)
                     /gene="gltA"
                     /locus_tag="IT892_002407"
     CDS             complement(15019..16302)
                     /gene="gltA"
                     /locus_tag="IT892_002407"
                     /EC_number="2.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (Si)-synthase"
                     /protein_id="HAP3135615.1"
                     /translation="MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFD
                     PGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYD
                     EFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
                     AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILER
                     AMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKML
                     EEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKD
                     DLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGW
                     IAHWSEMHSDGMKIARPRQLYTGYEKRDFKSDIKR"
     gene            complement(16508..16615)
                     /locus_tag="IT892_002408"
     CDS             complement(16508..16615)
                     /locus_tag="IT892_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135616.1"
                     /translation="MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV"
     gene            16996..17400
                     /gene="sdhC"
                     /locus_tag="IT892_002409"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
     CDS             16996..17400
                     /gene="sdhC"
                     /locus_tag="IT892_002409"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HAP3135617.1"
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFV
                     AVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFG
                     YLEETFEAGKRSAKISFVITVVLSLLAGVLVW"
     gene            17394..17741
                     /gene="sdhD"
                     /locus_tag="IT892_002410"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
     CDS             17394..17741
                     /gene="sdhD"
                     /locus_tag="IT892_002410"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="HAP3135618.1"
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELT
                     YEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALV
                     VYVIYGFVVVWGV"
     gene            17741..19507
                     /gene="sdhA"
                     /locus_tag="IT892_002411"
     CDS             17741..19507
                     /gene="sdhA"
                     /locus_tag="IT892_002411"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HAP3135619.1"
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRS
                     HTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHM
                     GLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
                     FSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHIN
                     TGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERY
                     APNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELS
                     RTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACV
                     SVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNN
                     RNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNT
                     QRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESM
                     TRRSVNMEPKLRPAFPPKIRTY"
     gene            19523..20239
                     /locus_tag="IT892_002412"
     CDS             19523..20239
                     /locus_tag="IT892_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit"
                     /protein_id="HAP3135620.1"
                     /translation="MRLEFSIYRYNPDVDDAPRMQDYTLEADEGRDMMLLDALIQLKE
                     KDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRD
                     LVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
                     SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPK
                     GLNPTRAIGHIKSMLLQRNA"
     gene            20540..23341
                     /gene="sucA"
                     /locus_tag="IT892_002413"
     CDS             20540..23341
                     /gene="sucA"
                     /locus_tag="IT892_002413"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HAP3135621.1"
                     /translation="MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRST
                     FQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFR
                     GHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEAL
                     KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLG
                     AKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQ
                     DLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSV
                     RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQV
                     GFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFI
                     DLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNL
                     YRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPE
                     AVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFF
                     HRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIW
                     EAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQL
                     CAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT
                     FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAM
                     QEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGY
                     MSVHQKQQQDLVNDALNVE"
     gene            23356..24573
                     /gene="odhB"
                     /locus_tag="IT892_002414"
     CDS             23356..24573
                     /gene="odhB"
                     /locus_tag="IT892_002414"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HAP3135622.1"
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDK
                     VVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQ
                     QASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAP
                     AAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRK
                     QYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTP
                     RGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMS
                     TPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIK
                     ELLEDPTRLLLDV"
     gene            24939..26105
                     /gene="sucC"
                     /locus_tag="IT892_002415"
     CDS             24939..26105
                     /gene="sucC"
                     /locus_tag="IT892_002415"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HAP3135623.1"
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWV
                     VKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAAT
                     DIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
                     RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGA
                     DGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIV
                     KLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIG
                     AVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK"
     gene            26105..26974
                     /gene="sucD"
                     /locus_tag="IT892_002416"
     CDS             26105..26974
                     /gene="sucD"
                     /locus_tag="IT892_002416"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HAP3135624.1"
                     /translation="MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKG
                     GTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPT
                     LDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYE
                     AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEA
                     AAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRS
                     LADIGEALKTVLK"
     gene            complement(27078..27800)
                     /gene="mngR"
                     /locus_tag="IT892_002417"
     CDS             complement(27078..27800)
                     /gene="mngR"
                     /locus_tag="IT892_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-D-glycerate transport/metabolism system
                     transcriptional repressor MngR"
                     /protein_id="HAP3135625.1"
                     /translation="MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRV
                     TVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVDTHSEVLIF
                     EVIPADDFLQQQLQITPQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENS
                     KYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEY
                     SRNAFNTDDYKFTLIAQRKSSR"
     gene            27909..29885
                     /gene="mngA"
                     /locus_tag="IT892_002418"
     CDS             27909..29885
                     /gene="mngA"
                     /locus_tag="IT892_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HAP3135626.1"
                     /translation="MVLFYRAHWRDYKNDQVRIMMNLTTLTHRDALCLNARFTSREEA
                     IHALTQRLAALGKISSTEQFLEEVYRRESLGPTALGEGLAVPHGKTAAVKEAAFAVAT
                     LSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATT
                     PDELLSALDDKGGTQPSASFSNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVY
                     VEKQGANGIEGRLTADQLNSATACIFAAEVAIKESERFNGIPALSVPVAEPIRHAEAL
                     IQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLL
                     SQIFGLQDLFNEENSWLWMYRKLGGGLLGILMVPVLAAYTAYSLADKPALAPGFAAGL
                     AANMIGSGFLGAVVGGLIAGYLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLML
                     FVVGEPVAWINNSLTAWLNGLSGSNALLLGAILGFMCSFDLGGPVNKAAYAFCLGAMA
                     NGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPM
                     AIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWF
                     GAALVGAAISTAILLMWRRHAVKHGNYLTDGVMP"
     gene            29903..32536
                     /gene="mngB"
                     /locus_tag="IT892_002419"
     CDS             29903..32536
                     /gene="mngB"
                     /locus_tag="IT892_002419"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HAP3135627.1"
                     /translation="MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQD
                     NEYKYYVLDGQTAILEDYFAVKPENKDRVKKQVEAGKLIIGPWYTQTDTTIVSAESIV
                     RNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
                     TEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLP
                     NGHDQMPLQQNIFEVMDKLREIYPQRKFVMSRFEEVFEKIEAQRDNLATLKGEFIDGK
                     YMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEYHHGLLEKMWKEILK
                     NHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNL
                     MPWPREEVINTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPF
                     MEFDIQINQIVPSMGYRTLYIEANQPGNVIAAKSDAEGILENAFWQIALNEDGSLQLV
                     DKDSGVRYDRVLQIEESSDDGDEYDYSPAKEEWVITAANAKPQCDIIHEAWQSRAVIR
                     YDMAVPLNLSERSARQSTGRVGVVLVVTLSHNSRRIDVDINLDNQADDHRLRVLVPTP
                     FNTDSVLADTQFGSLTRPVNDSAMNNWQQEGWKEAPVPVWNMLNYVALQEGRNGMAVF
                     SEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLLLRPGRPSGIKMPVPDSQLRGLLSC
                     RLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDVMKLNKAGFNVPESYSLLKMPP
                     VGCLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQ
                     GSNLSGPFLPGQSRTFSYRLA"
BASE COUNT         8126 a         8119 c         8842 g         7946 t
ORIGIN      
        1 ttatcggata ttctactgtt gactatttgt gccgttattt ctggtgcaga aggctgggaa
       61 gatatagagg attttgggga aacacatccc gattttttga agcaatatgg tgattttgaa
      121 aatggtattc ctgttcacga taccattgcc agagttgtat cctgtatctg tcctgcgaaa
      181 tttcatgaga gctttattaa ctggatgctt gactaccatt cttcagatga taaagacgtc
      241 atcgcaattg atggaaaaat acaccggcat tcttatgaca agagtcgccg taagggagcg
      301 attcatgtca ttagtgcgtt ctcaacaatg cacagtctgg tcatcggaca gatcaagacg
      361 gataagaaat ccaatgagat cacagctatc cctgaacttc ttaacatgct ggatattaaa
      421 ggaaaaatca tcaaaaccga tgcgatgggt tgccagaaag atattgcaga gaagatacaa
      481 aaacagggag gtgattattt attcgctgta aaaggaaacc aggggcggct aaataaagcc
      541 ttcgaggaaa aatttccgct gaaagaatta aataatccca agcatgacag ttacgcaatt
      601 agtgaaaaga gtcacggcag agaagaaacc cgtcttcata ttgtttgcga tgtccctgat
      661 gagcttattg atttcacgtt tgaatagaaa gggcagctat ggttagaaac tacctgacgt
      721 cagtccttgc ggggagcagg ctttcgtaaa tttgtcctgc tacaacagga ttaacttcac
      781 aaatatcatt tctcaacgtc tacacttact cctgtaaacc gctcaggagc agtaatgaat
      841 ctacaacgat ttgatgacag caccctaatc cgtatctttg cccttcatga gttacatcga
      901 ctgaaagaac atggcttaac gcgcggggcg cttctcgatt atcacagccg ctataaactc
      961 gtctttctgg cgcattctca gccggagtac cgcaaacttg gcccgttcgt ggctgatatt
     1021 caccagtggc aaaatctgga tgactattac aaccagtacc gccaacgcgt agttgttttg
     1081 ctttctcacc ccgccaaccc gcgcgatcac accaatgttt tgatgcacgt tcagggttat
     1141 tttcgcccgc atattgattc cacagaacgc cagcagctgg ctgcgcttat cgacagttat
     1201 cgccgtggcg agcaaccact tcttgcgccg ctgatgcgta tcaaacacta tatggcgctt
     1261 tatcctgacg cctggctttc agggcagcgt tatttcgaac tttggccgcg tgtgattaac
     1321 ttgcgccatt caggagtttt atgactaccc atctggtctg gtttcgccag gatttacgtc
     1381 tgcacgataa tctcgcactg gctgccgcct gccgcaattc gtctgcacgc gtgctggcgt
     1441 tgtatatcgc tacaccacgc cagtgggcga cgcataacat gtcgccgcgt caggctgaac
     1501 ttatcaatgc tcaactgaat gggctacaaa tagcgcttgc ggaaaaaggt attcctttat
     1561 tgttccgtga agtggatgac tttgtcgcca gtgtcgaaat agttaaacag gtgtgcgcgg
     1621 aaaacagcgt tacccacctg ttttataact atcagtatga agtgaatgag cgggcgcggg
     1681 atgtggaagt tgaaagagcg ctgcgtaacg tggtgtgtga aggatttgat gacagcgtga
     1741 tcctgccgcc tggcgcggtg atgaccggta atcacgagat gtacaaagtc tttacgcctt
     1801 ttaagaatgc ctggctgaaa cggctgcggg aagggatgcc ggagtgcgtc gctgcgccaa
     1861 aagttcgtag tagcggatcg atagagccct cgccatccat tacgctgaat tatcctcgtc
     1921 agtctttcga tactgcgcat tttccggtgg aagaaaaagc ggcgattgcg caattacgcc
     1981 agttttgcca gaacggtgcc ggagaatatg agcaacaacg agattttccg gcagtggaag
     2041 gcaccagccg tttgtcggcc agcctggcaa cgggcgggtt atcgcctcgc cagtgcttgc
     2101 atcgcttgtt ggctgaacag ccgcaggcgc tggacggtgg ggccggtagt gtctggctta
     2161 atgagctgat ctggcgcgag ttttaccgtc acctgataac gtatcacccc tcgttgtgta
     2221 aacatcgtcc atttattgcc tggacggatc gtgtacagtg gcagagcaat cccgcacatt
     2281 tacaggcctg gcaggaaggc aaaacgggat acccgattgt tgatgccgct atgcgtcagc
     2341 ttaacagcac tggctggatg cataacaggc tacggatgat tacagccagt tttctggtga
     2401 aagatttatt gatcgactgg cgcgaaggcg agcgatattt catgtcgcag ctgattgatg
     2461 gtgatttggc agccaataac ggtggctggc agtgggccgc ttcaaccgga accgatgcag
     2521 cgccgtattt tcgtattttc aacccgacaa cccagggcga gaaatttgat catgagggcg
     2581 agtttatccg ccagtggcta ccggaactgc gcgatgtgcc agggaaagtg gtgcatgagc
     2641 cgtggaagtg ggcgcagaaa gcaggtgtga cgctggatta tccgcaaccg atagtcgagc
     2701 acaaagaagc gagagtacaa acgttggcag cgtatgaggc ggcgcggaag gggaaataac
     2761 agacgcgtca ggcaatcgag cccagatgcc ggatgcggcg tgaacgcctt atccagccta
     2821 caaatttgtg caaattcaat aaattgcagg aaatacgtag gcctgataag acgcgtcaag
     2881 cgtcgcatca ggcatcggtg ctggcctatt aagactccag cgccagcgcg cggtttctga
     2941 atttcagcgc ctgatacagc caaatcatca gtaccagtcc tacacacgcc agtgcgcccc
     3001 aggtaatttg atcaaatact tcaatatatg cattgatgga gtagttgatc gccccggaag
     3061 catcaaacga agcctgcgat gtctgatcgg caatcacgcc cgccagatag ttcgcgatcg
     3121 cgccagaaag cagcatgtag atgccggtta atacgccggt cacaccgggg atttcaatgc
     3181 gcgtaatttg cgacatggca accgggtcga taaacagttc cgcaaagccc atcaccgcca
     3241 ggcctaatac catcagtggc agagaagagt gaccatacat tgcggaccag cgggcgctta
     3301 aggtcagaat gcagaatccg gcgctcatca ggccaaggcc aagagcaaat ttcccccaga
     3361 tgcgcacggt acgattaccc gcgacactct cttttaccac ccacgccagg aacacaccgc
     3421 acagcataac tgcgaaggca ttaatcgact ggaacatcgc ggtcggaacg gtataaccaa
     3481 acatatcgcg gttaacgaag cggtcgatat aaaggctaat cgagctaccg ccctgttgtg
     3541 cgaaggccca gaacaacata ctgaagaagg tgagcgtcac aatcagcccc agctccttcc
     3601 gctgtttctg gttttctgct ttgcgataaa tttttgccag tacacccagg ccaataatag
     3661 tcgcgacaat taaggcgtat accgaccact ctttccagaa cagtatggta atcagtgcag
     3721 gcgttgccac cagcagaacc agcagccatc cccagttcgg caggagaaag tttgtcgcac
     3781 gcagtacttt tttgttaacg ccgcgggtat gagtgaaatg acgattgcca cataagaaaa
     3841 tgaccagacc cgcgatcatg ccaaccgccg ccaggccaaa gcccatcgcc cagctgtact
     3901 cttcctgggc gtaaccacag gcgataggtg cgataataga ccccacgtta cccgccgcat
     3961 acatcagcga gaaaccgcca tcacgacgcg gatcggttgg ctcatacagc tcgccgagca
     4021 gacagcttac gttagattta aacaggccat agccgcagac gataatcgcc agggacagat
     4081 agaggaatga cggatggatc tcactggcac ccagcaccac atgaccgatc gccatcaaca
     4141 acgcccccag catcaccgcc atgcgattgc cgagaacttt atccgccaaa aagccaccga
     4201 ggattggcgt gacatacacc agcgaacagt aggcgctaaa taactcgtag gcgtgagtat
     4261 cgttgtattt tagttgattg gtgagataga gaatcagcag ggcacgcatg ccgtaaaagc
     4321 taaaatattc ccagatttgc agcgcaacga catagtaaat agcgcgcggc tgtgatgcgt
     4381 gtttattcat aataattcca caattgacgg caacgtcacg taatagttgc gcggcgtgct
     4441 tgtgtttcct taaagttaaa actttgatac agatctgatt atttatgcaa tatgctgtct
     4501 gattgcataa atatacatta gctgaagcgt gatgatataa acaatttgcg tcttttggcg
     4561 tcgggtttgt ttcttaatat gtcaaaagat tggctatcga cgaactggcg aggtaacgct
     4621 atgttaacgg tgtagctatc agaatacgga aggcgcgaag atgaaaaaca ccgaactgga
     4681 acaactgatt aacgaaaaac tgaacagcgc ggcgattagt gattacgcgc cgaatggttt
     4741 gcaggtggaa ggcaaagaga cggtgcaaaa aattgttacc ggtgtcaccg ccagccaggc
     4801 tttgctcgat gaggcagtgc gtctgggcgc ggatgcggtc attgtgcatc atggctactt
     4861 ctggaaagga gagtctccgg tcattcgcgg aatgaagcgt aaccgtttaa aaacgttgct
     4921 ggcgaatgat atcaacctgt atggctggca tttgccgctt gacgcacatc ctgagctggg
     4981 caataacgca cagctggcgg cgttactggg gatcacggtc atgggcgaaa ttgagccgtt
     5041 ggtgccgtgg ggcgaactga ccatgcctgt gccgggactg gagctggctt cctggattga
     5101 agcgcgtctg ggacgtaagc cgttatggtg tggcgatacc ggacctgagg tggtccagcg
     5161 cgtcgcctgg tgcacgggcg gcgggcaaag ttttatcgat agcgccgcgc gttttggcgt
     5221 ggatgctttt attactggcg aagtttctga acagaccatt cattcagccc gcgagcaggg
     5281 attgcatttt tatgctgcag gtcaccatgc cactgaacgt ggtggtattc gcgcattgag
     5341 cgagtggctg aatgaaaata ccgatcttga tgtgaccttt attgatattc ctaatcctgc
     5401 ataacgaata atcagaggga tcgaaagtgc aacgagcgcg ttgttatctg ataggtgaaa
     5461 cggcggtagt gctggaactg gaaccgccgg tgacgctggc tagccagaaa cggatctggc
     5521 gactggcgca gcgtctggtg gatatgccga atgtggttga agccattccc ggcatgaaca
     5581 atatcacggt gattttgcgt aatcctgagt cgctggcgct ggatgccata gagcgtttgc
     5641 aacgctggtg ggaggagagc gaggcgctgg agccggagtc tcgctttatt gaaattccgg
     5701 tggtttacgg tggtgcaggc ggaccggatt tggcggtggt cgcggcgcat tgcgggttga
     5761 gcgaaaaaca ggttgttgaa ttgcactcct ccgtggaata cgtggtctgg tttttaggtt
     5821 ttcaaccggg cttcccgtat ctcgggagtt tgccggaaca actacacacg ccacggcgcg
     5881 ctgaaccgcg cttactcgtt ccggcaggtt ctgtcgggat cggcgggccg cagactggtg
     5941 tttatccgct ggcaacgccg ggtggctggc agttgattgg tcatacctca ctcagcctgt
     6001 ttgatccggc gcgtgacgaa cccatcttat tacgtccggg agacagcgtg cgctttgtac
     6061 cgcagaagga gggagtatgc tgaagattat tcgtgcgggc atgtatacca ctgtgcagga
     6121 tggcggtcgt cacggttttc gccagtcggg tatcagccac tgcggcgcac tggatatgcc
     6181 cgcgttacgc attgctaacc tactggtggg taatgacgcc aatgcccccg cgctggagat
     6241 cacgctcggt cagttaactg ttgagttcga aactgatggg tggtttgctc tgacgggtgc
     6301 cggttgcgaa gcgcggctgg atgataatgc cgtctggacc ggctggcgat tgccgatgaa
     6361 agcaggccag cgtttaacgc ttaaacgccc gcagcacggg atgcgcagtt atctggcggt
     6421 cgcgggtggt attgatgttc cgccggtaat gggctcatgc agcaccgatc tcaaagtggg
     6481 gattggcggg ctggaaggcc gtttactgaa ggatggtgac cgactcccga ttggcaaatc
     6541 gaagcgtgat tctatggaag cgcagggcgt taaacagctg ctgtggggca accgcattcg
     6601 cgccttgccg gggccggaat atcatgagtt cgatcgcgcc tcgcaggatg cattctggcg
     6661 ttcgccctgg cagcttagct cgcaaagtaa ccgcatgggc tatcgcttac aggggcaaat
     6721 tttaaaacgc accaccgatc gcgaactgtt atctcacggt ttgttaccgg gcgtggtgca
     6781 ggtgccacat aacgggcagc cgattgtgtt gatgaacgac gcacagacca ccggtggtta
     6841 cccgcgtatt gcctgtatca ttgaggctga tatgtaccat ctggcgcaaa ttccgctcgg
     6901 tcagccgatt cattttgtcc agtgttcact ggaagaggca ctaaaagcac ggcaagatca
     6961 gcaacgttat tttgaacaat tagcgtggcg gctgcacaat gaaaattgac ctgaacgccg
     7021 atctgggcga aggctgcgcc agcgacgcag agctattaac gctggtttcc tctgccaata
     7081 ttgcctgtgg atttcatgca ggcgatgcgc aaatcatgca ggcttgcgtg cgtgaagcaa
     7141 taaaaaatgg tgtcgcgatt ggcgctcacc cgagttttcc cgacagggaa aattttggtc
     7201 gcagcgccat gcagctgccg ccagaaaccg tttacgccca gacgctgtat caaattggcg
     7261 cgctggcaac gattgcccgt gcgcaaggcg gcgtaatgcg tcatgtcaaa ccgcacggca
     7321 tgttgtacaa ccaggcggcg aaagaagcac aactggcaga cgccatcgcc agagcggtat
     7381 acgcttgcga tccagcattg attctcgtcg ggctggcggg aagcgagctg attcgtgcag
     7441 gcaagcaata tggtctgaca acgcgcgagg aagtgtttgc cgatcgcggt tatcaggctg
     7501 acggctcgct ggtgccgcga agccagtcag gcgcgttgat tgaaaacgaa gaacaggcgc
     7561 tggcgcaaac gctggagatg gtgcaacacg gcagagtcaa aagtatcacc ggcgaatggg
     7621 caacggtcgc ggcgcaaacg gtctgcctgc atggcgacgg cgagcacgca ctggcgttcg
     7681 cccgccgact acgctctgca tttgccgaaa aggggattgt tgtcgcagca taaccccgat
     7741 taataaagaa tgaaaaaagg atatcaccat gcctgaaggc ccggagatcc gccgtgcagc
     7801 ggataacctg gaggcggcga tcaaaggcaa accactaact gatgtctggt ttgccttccc
     7861 gcagttaaaa ccttatcaat cacaacttat cggtcaacac gttacccatg tggaaacgcg
     7921 tggtaaggcg ttgttaactc atttttccaa cgacttaacg ctctacagcc ataatcagct
     7981 ttacggcgtc tggcgcgtgg ttgataccgg cgaagagccg cagaccacgc gagtattgcg
     8041 ggtaaaactg caaacggctg acaaaaccat tctgctttat agcgcctcgg atattgagat
     8101 gttgaccccg gaacaactga ccacgcatcc gtttttacaa cgcgttggtc ccgatgtgct
     8161 ggatccgaat ctgacgccgg aggtggtgaa agaacgatta ttgtcgccgc gctttcgtaa
     8221 ccgtcagttt gctggattac tgctcgatca ggcgtttctg gctgggcttg gcaattattt
     8281 gcgggtggag atcctctggc aggttgggtt gactggaaat cataaagcga aagatctcaa
     8341 tgcggcgcaa ctggatgcac tcgcacacgc gttactggag attcctcgat tttcctacgc
     8401 tacgcggggg caggtggatg agaataagca tcatggggcg ctgtttcgct ttaaggtttt
     8461 tcatcgagat ggcgaaccgt gcgaacgttg tggcagcatc attgagaaaa ccacgctgtc
     8521 atctcgcccg ttttactggt gccctggctg ccagcactag gccgaccgct tcggcgcata
     8581 ggttgaaata aaccgcgcaa tggcaggccc tgtcagcaaa atactgaaca ggcgtagggt
     8641 ttgcatcgcc ataatgagcg ccatatcggc attgctccct gcggcgatga ccgccacggt
     8701 atcaagcccg ccggggctgg tggcgaggta ggcagtcata aaatcaatgt gcataaaccg
     8761 ggtcagcccc cacgccatac ccgcacaaat agccagcaga gcaaaaatcg acagcaggat
     8821 ttgcggtagc gggcgtagtg cccgcagtaa gatttgttta tcgaaaccaa gaccaatccg
     8881 ccagccaatt gccatatacg ccatcgccag cagccattcc ggtagttcga tggtgatgag
     8941 ctgaccagac tggagcactg cgcccgccag catcgggatg agcatcgtgc cggaaggaag
     9001 acgcagcagg catcccactg taccggcaac gaccgcgagc aaaatagtaa gcaggagatt
     9061 aatgctcact ggcgggaacc agacgatatg ctggttaacc gcttcagcgt tatcgcccag
     9121 catcatgcgg gtgaccagaa cagcggcccc cgcgacgaac agcactcgca gatattgcat
     9181 aaacgccacc aggcgaatat ctgcgccgta atcttgcgcc atagcgacca ttgccgccgc
     9241 gccgccagga gaggagcccc aggcaccggt atttccaggc aatgagctat agcgcaccaa
     9301 taaccaaccc acaatggcgc tggaaagcag cgttaccagt aaaattgcaa gcacgatcgg
     9361 ccagttgacg gccagggtgg tgagaatcga accagtgagg ttttgcgcaa tcatgcagcc
     9421 aagaatggcc tgggcggcga gaaaagcaga gcggggaagt tgcagagtaa ttccgcgcat
     9481 actaaagatg atcccggcga tcatcggccc aagtaatagc gccgccggga gatgtaccgc
     9541 gaggaaacca atagaaagga gaagtgatag cacacataac attccccact gcaaaactgg
     9601 catccttcgc tccctcatta ttttctcttt ggtgtatcga tacagcataa agaaagctgg
     9661 gccaggaaaa aataacagca atcaaggaaa aggggaaaat cagcaatttt ctgaaagaga
     9721 tgccctttcc ggcggcaaag ggcatcatgg taaatcagtt atagttaatc ttaaaaagca
     9781 ccactgtatc gaaggggcca gcctcgatgg gggtgcctgg aatggacgaa agttcagccg
     9841 tataggtttt ttcgtagacc aacatgtcac tggtgaaatc ggcgtattca gcatatttat
     9901 tgaaggtata aggcgaggcg ttttcatcca gtaaacgtag cttcagacca ttaccaatca
     9961 acaatgcttt atcttcttca accaacgttt cttcggtata aaaggaggaa ctgactttaa
    10021 atccgtcggt gcattgatcg ttttggctct tggtcgtttt aatactgaac gttttcgaca
    10081 ttgtgtggcg acgtatatcc agcaaattaa atttaccaaa atcaatcacc tgtgtttccg
    10141 gtgaaatgga aaaattgacg ctgcaatcca gcacgcgaat gttttccaga ccagtaatat
    10201 gatatttcag gttttgggca gtagggtctt cgttaacgct accggcaccg tcaaattgca
    10261 cgacgatata gtcgctaagc gtactttgat aatcatgcgg cggcatttct cgtattttga
    10321 cgtataaccg catgcgagcg agaaaggtac gcgacatatg aatattagcg ggatcgcccg
    10381 agcaaatttt gttctgccat cccatcgcga tgatctgctc aggggtataa atatcaatgt
    10441 tcttactgtc gatacactgg ttagtgtcga tgcgactttt tcccagactg gcatcgtaat
    10501 cgacaccgtt gtatgtcacg ccgagttgat aataacgatc ctgcaccccc ggataggggt
    10561 ttacccaggc gtagacatgc tcgctttcaa agttgccgtt ggtattgttg tcacaataga
    10621 cgggaatttt aatatcgtca gattcccaga tcttatcacc gggtttggca ttgcctggta
    10681 cagcaaacgg ttgaatcgct tctgattttt ctactgcgcc accagatgta ccaaaatagc
    10741 agttcagcgc cattgcagac ttcaacggca gaaataacag gcagatgacg agcaacaatc
    10801 ccttgccagc actcatttcg cctccactgc ttgtaaacgg cattgtccgc tgcagttgag
    10861 cgtcgtcatg cgtaatgcgc cgtaatcatc catgtaaccg agataaaact ggctgccgct
    10921 ataacttccg gtgtttgtgt tgaccgtact aaaaggtgca accatcacgg ttttgaagcc
    10981 tgggagaacg cctttttcat ttctccccag ataggcaatg gtcagataat acgcggtagg
    11041 atttttcagt gtcagttggt tgccctgctg gctgacctgt aactgcagtt cgaccttttc
    11101 tcctgctttc ttgcgtaatg cagccggtcg ccagaacaat ttaatacgac tttgaatagc
    11161 gacctgaagt atcgcatggt cgctgctttt atccggagcg ggaggaattt cgcgcatatt
    11221 gtagaaaaat agcgtttcgc gatcgccagg taattgtgtg gttgaggctt gtttcacaac
    11281 ccgcacctgc gatgtcgctt tcggttccag acgttgaata gggggcaaag cgaccagaag
    11341 agcatcgctt ttctcccctt tttcattttc tatccaggaa taagcaagat aaggcagttt
    11401 gtcactttgg ttttcgatac gcaggctggt ggctttgtca ttggcgttaa acacaatgcg
    11461 tgtgcgatcg ggttgcaccg cagcattgca acccaagctg atggttaaca acattaaggg
    11521 taatccttta ataaatgtca ttctcttttc cttaattaat gacaaggtaa aatcaggcgt
    11581 ttggtcgtgt cttccagacg ttctggcaga tgaataatgc agctttgctc accccagacc
    11641 acggtaaaca gttgattttc agcgacaccg cttaaccagg catgtccttc ctcgccaacc
    11701 atacccacgc taatgccgct gtcatcctgg cggatatccg caccgagggg agggaactga
    11761 ccgctggcgt tgcgtatgat gacgttaacg tctttaccgg aacgggaagc cagtgatttg
    11821 taacctatcg cgccttcaat ccatgtttcc ttgatgacgt tttctgcaac tgttacgccg
    11881 tcgggtaagt cattcatgtt caccgccacg gtggaaggct ggtaactgga aatcaacggc
    11941 accaccgcaa tgccaaaatg gttggtgtag tcgagattgc cctgaaccgg aatatctgcc
    12001 acgccatcgg tgctgaccat caggcgtggt tcattggtgg agctgcggcg atgaaatgct
    12061 gcaccatatt gggttgcggt gaaagaaccg ctccagctgc tgctgacgga actgtaatca
    12121 ctggcggcat aggtaccaga aatatcccac tcacccgctg aactcaggtg ctgatagtta
    12181 ccgctcacct gggctccatt gtccggacga tcggattgca gtccggcaga catgccccag
    12241 ctattacgtt catccagcgt atcgttccac gacatgcggt gtatggtgct gtggctactg
    12301 ttttgcatgt catagccaac ccgaccaccg ttaccgaagg ggagcgaaat cgacagataa
    12361 atctggttgt cgcgatcttt atcttcgtag tgggtcgtat tgaatgacgt cgaaatcgag
    12421 atatctctcc agtcaccaat atcaacatta aaacctgctg tgatgttggc ggtcgtggag
    12481 gcgtctgcat tccaccaggt ttgatgtagc aggttggcgt aaagattgag gtttagtggg
    12541 gtaatcggtt ggcccacgga taagctgatc gtctgttttt cgtcctgcgc atcgctgtcg
    12601 ttgtatttgt gatccagata gttggcgtag ctgtgaaaat gacgatctga gaagcgataa
    12661 gcggcgagcg aaatcgtgct gttggtggca tccacttgtt tgctgtaatt aaaacggtag
    12721 cttaagcccc gctcgtcctg ctgagtatca aaatggctac tggcccaggt gacatcaaag
    12781 gacagtgcgc caagccacag catattttgc ccgataccca ttgcggcaga atggtagtca
    12841 tcatcagaaa tcagcaggcc gccgtacagc gaggtgtttg agagcatccc ccaggaaact
    12901 tcattgctaa aaaaggtttc attttcagtt tgatgtgaca tggaaggccg tggctgaccc
    12961 gcggccaatt tatagcgaac ctgtccctgg cgagtcagga agggcgtcga tgctgccgaa
    13021 acctggaaat tgttcacccg accatcttct tccgtcactt tgacatccag cgtgccctga
    13081 acagactgat tgaggtcatc aataataaac gggcctggcg ggactttttt ctggtaaatg
    13141 acgcggcctg attgactgat cgtcaccgtg gcattggtct gtgcaatacc gctaatttgt
    13201 ggggcgtagc cacgcagctc ccacggtaac attcgatcgt cactcgccag tgccgcgccg
    13261 gtataagaaa aaccatcgaa aatattggaa ctgaaatcgg tttcgccgag ggttaactta
    13321 gagcctaatt gcggtaatgg acgaaaaaga taggtgcgcg atattccgcc tgactggtca
    13381 tggttatctt cgctatcggt cttattaagc tggtaatcac tgcgtaagcg ccatgccccg
    13441 gcgttaattc cggcggtacc gtaggcattc aggttagtgc tgctgctgcc gtcctgtggg
    13501 cggtagctgc tggcaaacaa gttgtaatcc atcaggacac cggcaacacc ttctttccat
    13561 gtagaggggg gagcccagtt ttctgagtgc cacgccagcc aggcttgcgg aatactaata
    13621 ttcagttgct gattggcttg atcgaaattg aagagcattt caggtcggga actgaaatca
    13681 atacaccgat ctatctgtgg caaggactga cggatatctg gttttaaacc aaatttatcg
    13741 accagtgaat cattgatgca tggaatggtt ttgtcaccct ttttttgcca gttaattttt
    13801 tgcccattac tgattttgtt gttattcacc gcaacgctaa caaaatattc accgggagca
    13861 atgactcctt tttcctttaa taatgaaata tcaatgcggt cgcgcattga tttatcgaga
    13921 acattcagat tgaattcgac cgccattgcg caaggcatcg ccatgaccag gcaggataca
    13981 aaagagagtc gataaatatt cacggtgtcc atacctgata aatattttat gaaaggcggc
    14041 gatgatgccg ccaaaataat acttatttat aatccagcac gtaggttgcg ttagcggtta
    14101 cttcacctgc cgtgacatcg actgcattat caatttgttc catccaggcg aaaaagttca
    14161 gcgtctgttc tgatgagctt gcatccaggt caagatctgg cgcggctgaa cctaatacga
    14221 tgttaccgtc atttttgtcc atcagtcgta caccgacccc agttgcttcg cctgcactgg
    14281 tgttgctcaa caaaggcgta gcaccagttg tcttagccgt gctatcgaag gttacgccaa
    14341 ctttggatac cggcattccg ctaccgttgt cagaagcagg cagatcacag ttgatcaagc
    14401 gaatgtcgac ggccacttta ttgctatgat gctcccggtt tatatgggtt gtcgtgactt
    14461 gtccaagatc tatgttttta tcaatatctt ctggatgaat ttcacaaggt gcttcaataa
    14521 cctccccctt aaagtgaatt tcgccagaac cttcatcagc agcataaaca ggtgcagtga
    14581 acagcagaga tacggccagt gcggccaatg ttttttgtcc tttaaacata acagagtcct
    14641 ttaaggatat agaatagggg tatagctacg ccagaatatc gtatttgatt attgctagtt
    14701 tttagttttg cttaaaaata ttgttagttt tattaaatgc aaaactaaat tattggtatc
    14761 atgaatttgt tgtatgatga ataaaatata ggggggtata gatagacgtc attttcatag
    14821 ggttataaat gcgactacca tgaagttttt aattgaaagt attgggttgc tgataatttg
    14881 agctgttcta ttctttttaa atatctatat aggtctgtta atggatttta tttttacaat
    14941 tttttgtgtt taggcatata aaaatcaacc cgccatatga acggcgggtt aaaatattta
    15001 caacttagca atcaaccatt aacgcttgat atcgctttta aagtcgcgtt tttcatatcc
    15061 tgtatacagc tgacgcggac gggcaatctt cataccgtca ctgtgcattt cgctccagtg
    15121 ggcgatccag ccaacggtac gtgccattgc gaaaatgacg gtgaacatgg aagacggaat
    15181 acccatcgct ttcaggatga taccagagta gaaatcgacg ttcgggtaca gtttcttctc
    15241 gataaagtac gggtcgttca gcgcgatgtt ttccagctcc atagccactt ccagcaggtc
    15301 atccttcgtg cccagctctt tcagcacttc atggcaggtt tcacgcatta cggtggcgcg
    15361 cgggtcgtaa tttttgtaca cgcggtgacc gaagcccatc aggcggaaag aatcattttt
    15421 gtctttcgca cgacgaacaa attccggaat gtgtttaacg gagctgattt cttccagcat
    15481 tttcagcgcc gcttcgttag caccgccgtg cgcaggtccc cacagtgaag caatacctgc
    15541 tgcgatacag gcaaacgggt tcgcacccga agagccagcg gtacgcacgg tggaggtaga
    15601 ggcgttctgt tcatggtcag cgtgcaggat cagaatacgg tccatagcac gttccagaat
    15661 cggattaact tcatacggtt cgcacggcgt ggagaacatc atattcagga agttaccggc
    15721 gtaggagaga tcgttgcgcg ggtaaacaaa tggctgacca atggaatact tgtaacacat
    15781 cgcggccatg gtcggcattt tcgacagcag gcggaacgcg gcaatttcac ggtgacgagg
    15841 attgttaaca tccagcgagt cgtgatagaa cgccgccagc gcgccggtaa taccacacat
    15901 gactgccatt ggatgcgagt cgcgacggaa agcatggaac agacgggtaa tctgctcgtg
    15961 gatcatggta tgacgggtca ccgtagtttt aaattcgtca tactgttcct gagtcggttt
    16021 ttcaccattc agcaggatgt aacaaacttc caggtagtta gaatcggtcg ccagctgatc
    16081 gatcgggaaa ccgcggtgca gcaaaatacc ttcatcacca tcaataaaag taattttaga
    16141 ttcgcaggat gcggttgaag tgaagcctgg gtcaaaggtg aacacacctt ttgaaccgag
    16201 agtacggata tcaataacat cttgacccag cgtgcctttc agcacatcca gttcaacagc
    16261 tgtatccccg ttgagggtga gttttgcttt tgtatcagcc atttaaggtc tccttagcgc
    16321 cttattgcgt aagactgccg gaacttaaat ttgccttcgc acatcaacct ggctttaccc
    16381 gttttttatt tggctcgccg ctctgtgaaa gaggggaaaa cctgggtaca gagctctggg
    16441 cgcttgcagg taaaggatcc attgatgacg aataaatggc gaatcaagta cttagcaatc
    16501 cgaattatta aacttgtcta ccactaataa ctgtcccgaa tgaattggtc aatacttcca
    16561 cactgttaca taagttaatc ttaggtgaaa taccgacttc ataactttta cgcattatat
    16621 gcttttcctg gtaatgtttg taacaacttt gttgaatgat tgtcaaatta gatgattaaa
    16681 aattaaataa atgttgttat cgtgacctgg atcactgttc aggataaaac ccgacaaact
    16741 atatgtaggt taattgtaat gattttgtga acagcctata ctgccgccag gtctccggaa
    16801 caccctgcaa tcccgagcca cccagcgttg taacgtgtcg ttttcgcatc tggaagcagt
    16861 gttttgcatg acgcgcagtt atagaaagga cgctgtctga cccgcaagca gaccggagga
    16921 aggaaatccc gacgtctcca ggtaacagaa agttaacctc tgtgcccgta gtccccaggg
    16981 aataataaga acagcatgtg ggcgttattc atgataagaa atgtgaaaaa acaaagacct
    17041 gttaatctgg acctacagac catccggttc cccatcacgg cgatagcgtc cattctccat
    17101 cgcgtttccg gtgtgatcac ctttgttgca gtgggcatcc tgctgtggct tctgggtacc
    17161 agcctctctt cccctgaagg tttcgagcaa gcttccgcga ttatgggcag cttcttcgtc
    17221 aaatttatca tgtggggcat ccttaccgct ctggcgtatc acgtcgtcgt aggtattcgc
    17281 cacatgatga tggattttgg ctatctggaa gaaacattcg aagcgggtaa acgctccgcc
    17341 aaaatctcct ttgttattac tgtcgtgctt tcacttctcg caggagtcct cgtatggtaa
    17401 gcaacgcctc cgcattagga cgcaatggcg tacatgattt catcctcgtt cgcgctaccg
    17461 ctatcgtcct gacgctctac atcatttata tggtcggttt tttcgctacc agtggcgagc
    17521 tgacatatga agtctggatc ggtttcttcg cctctgcgtt caccaaagtg ttcaccctgc
    17581 tggcgctgtt ttctatcttg atccatgcct ggatcggcat gtggcaggtg ttgaccgact
    17641 acgttaaacc gctggctttg cgcctgatgc tgcaactggt gattgtcgtt gcactggtgg
    17701 tttacgtgat ttatggattc gttgtggtgt ggggtgtgtg atgaaattgc cagtcagaga
    17761 atttgatgca gttgtgattg gtgccggtgg cgcaggtatg cgcgcggcgc tgcaaatttc
    17821 ccagagcggc cagacctgtg cgctgctctc taaagtcttc ccgacccgtt cccataccgt
    17881 ttctgcgcaa ggcggcatta ccgttgcgct gggtaatacc catgaagata actgggaatg
    17941 gcatatgtac gacaccgtga aagggtcgga ctatatcggt gaccaggacg cgattgaata
    18001 tatgtgtaaa accgggccgg aagcgattct ggaactcgaa cacatgggcc tgccgttctc
    18061 gcgtctcgat gatggtcgta tctatcaacg tccgtttggc ggtcagtcga aaaacttcgg
    18121 cggcgagcag gcggcacgca ctgcggcagc agctgaccgt accggtcacg cactgttgca
    18181 cacgctttat cagcagaacc tgaaaaacca caccaccatt ttctccgagt ggtatgcgct
    18241 ggatctggtg aaaaaccagg atggcgcggt ggtgggttgt accgcactgt gcatcgaaac
    18301 cggtgaagtg gtttatttca aagcccgcgc taccgtgctg gcgactggcg gagcagggcg
    18361 tatttatcag tccaccacca acgcccacat taacaccggc gacggtgtcg gcatggctat
    18421 ccgtgccggc gtaccggtgc aggatatgga aatgtggcag ttccacccga ccggcattgc
    18481 cggtgcgggc gtactggtca ccgaaggttg ccgtggtgaa ggcggttatc tgctgaacaa
    18541 acatggcgaa cgttttatgg agcgttatgc gccgaacgcc aaagacctgg cgggccgtga
    18601 cgtggttgcg cgttccatca tgatcgaaat ccgtgaaggt cgcggctgtg atggtccgtg
    18661 ggggccacac gcgaaactga aactcgatca cctgggtaaa gaagttctcg aatcccgtct
    18721 gccgggtatc ctggagcttt cccgtacctt cgctcacgtc gatccggtga aagagccgat
    18781 tccggttatc ccaacctgtc actacatgat gggcggtatt ccgaccaaag ttaccggtca
    18841 ggcgctgact gtgaatgaga aaggcgaaga tgtggttgtt ccgggactgt ttgccgttgg
    18901 tgaaatcgct tgtgtatcgg tacacggcgc taaccgtctg ggcggcaact cgctgctgga
    18961 cctggtggtc tttggtcgcg cggcaggtct gcatctgcaa gagtctatcg ccgagcaggg
    19021 cgcactgcgc gatgccagcg agtctgatgt tgaagcgtct ctggatcgcc tgaaccgctg
    19081 gaacaataat cgtaacggtg aagatccggt ggcgatccgt aaagcgctgc aagaatgtat
    19141 gcagcataac ttctcggtct tccgtgaagg tgatgcgatg gcgaaagggc ttgagcagtt
    19201 gaaagtgatc cgcgagcgtc tgaaaaatgc ccgtctggat gacacttcca gcgagttcaa
    19261 cacccagcgc gttgagtgcc tggaactgga taacctgatg gaaacggcgt atgcaacggc
    19321 tgtttctgcc aacttccgta ccgaaagccg tggcgcgcat agccgcttcg acttcccgga
    19381 tcgtgatgat gaaaactggc tgtgccactc cctgtatctg ccagagtcgg aatccatgac
    19441 gcgccgaagc gtcaacatgg aaccgaaact gcgcccggca ttcccgccga agattcgtac
    19501 ttactaatgc ggagacagga aaatgagact cgagttttca atttatcgct ataacccgga
    19561 tgttgatgat gctccgcgta tgcaggatta caccctggaa gcggatgaag gtcgcgacat
    19621 gatgctgctg gatgcgctta tccagctaaa agagaaagat cccagcctgt cgttccgccg
    19681 ctcctgccgt gaaggtgtgt gcggttccga cggtctgaac atgaacggca agaatggtct
    19741 ggcctgtatt accccgattt cggcactcaa ccagccgggc aagaagattg tgattcgccc
    19801 gctgccaggt ttaccggtga tccgcgattt ggtggtagac atgggacaat tctatgcgca
    19861 atatgagaaa attaagcctt acctgttgaa taatggacaa aatccgccag ctcgcgagca
    19921 tttacagatg ccagagcagc gcgaaaaact cgacgggctg tatgaatgta ttctctgcgc
    19981 atgttgttca acctcttgtc cgtctttctg gtggaatccc gataagttta tcggcccggc
    20041 aggcttgtta gcggcatatc gtttcctgat tgatagccgt gataccgaga ctgacagccg
    20101 cctcgacggt ttgagtgatg cattcagcgt attccgctgt cacagcatca tgaactgcgt
    20161 cagtgtatgt ccgaaggggc tgaacccgac gcgcgccatc ggccatatca agtcgatgtt
    20221 gttgcaacgt aatgcgtaaa ccgtaggcct gataagacgc gcaagcgtcg catcaggcaa
    20281 ccagtgccgg atgcggcgtg aacgccttat ccggcctaca agtcattacc cgtaggcctg
    20341 ataagcgcag cgcatcaggc gtaacaaaga aatgcaggaa atctttaaaa actgcccctg
    20401 acactaagac agtttttaaa ggttccttcg cgagccacta cgtagacaag agctcgcaag
    20461 tgaaccccgg cacgcacatc actgtgcgtg gtagtatcca cggcgaagta agcataaaaa
    20521 agatgcttaa gggatcacga tgcagaacag cgctttgaaa gcctggttgg actcttctta
    20581 cctctctggc gcaaaccaga gctggataga acagctctat gaagacttct taaccgatcc
    20641 tgactcggtt gacgctaact ggcgttcgac gttccagcag ttacctggta cgggagtcaa
    20701 accggatcaa ttccactctc aaacgcgtga atatttccgc cgcctggcga aagacgcttc
    20761 acgttactct tcaacgatct ccgaccctga caccaatgtg aagcaggtta aagtcctgca
    20821 gctcattaac gcataccgct tccgtggtca ccagcatgcg aatctcgatc cgctgggact
    20881 gtggcagcaa gataaagtgg ccgatctgga tccgtctttc cacgatctga ccgaagcaga
    20941 cttccaggag accttcaacg tcggttcatt tgccagcggc aaagaaacca tgaaactcgg
    21001 cgagctgctg gaagccctca agcaaaccta ctgcggcccg attggtgccg agtatatgca
    21061 cattaccagc accgaagaaa aacgctggat ccaacagcgt atcgagtctg gtcgcgcgac
    21121 tttcaatagc gaagagaaaa aacgcttctt aagcgaactg accgccgctg aaggtcttga
    21181 acgttacctc ggcgcaaaat tccctggcgc aaaacgcttc tcgctggaag gcggtgacgc
    21241 gttaatcccg atgcttaaag agatgatccg ccacgctggc aacagcggca cccgcgaagt
    21301 ggttctcggg atggcgcacc gtggtcgtct gaacgtgctg gtgaacgtgc tgggtaaaaa
    21361 accgcaagac ttgttcgacg agttcgccgg taaacataaa gaacacctcg gcacgggtga
    21421 cgtgaaatac cacatgggct tctcgtctga cttccagacc gatggcggcc tggtgcacct
    21481 ggcgctggcg tttaacccgt ctcaccttga gattgtaagc ccggtagtta tcggttctgt
    21541 tcgtgcccgt ctggacagac ttgatgagcc gagcagcaac aaagtgctgc caatcaccat
    21601 ccacggtgac gccgcagtga ccgggcaggg cgtggttcag gaaaccctga acatgtcgaa
    21661 agcgcgtggt tatgaagttg gcggtacggt acgtatcgtt atcaacaacc aggttggttt
    21721 caccacctct aatccgctgg atgcccgttc tacgccgtac tgtactgata tcggtaagat
    21781 ggttcaggcc ccgattttcc acgttaacgc ggacgatccg gaagccgttg cctttgtgac
    21841 ccgtctggcg ctcgatttcc gtaacacctt taaacgtgat gtcttcatcg acctggtgtg
    21901 ctaccgccgt cacggccaca acgaagccga cgagccgagc gcaacccagc cgctgatgta
    21961 tcagaaaatc aaaaaacatc cgacaccgcg caaaatctac gctgacaagc tggagcagga
    22021 aaaagtggcg acgctggaag atgccaccga gatggttaac ctgtaccgcg atgcgctgga
    22081 tgctggcgat tgcgtagtgg cagagtggcg tccgatgaac atgcactctt tcacctggtc
    22141 gccgtacctc aaccacgaat gggacgaaga gtacccgaac aaagttgaga tgaagcgcct
    22201 gcaggagctg gcgaaacgca tcagcacggt gccggaagca gttgaaatgc agtctcgcgt
    22261 tgccaagatt tatggcgatc gccaggcgat ggctgccggt gagaaactgt tcgactgggg
    22321 cggtgcggaa aacctcgctt acgccacgct ggttgatgaa ggcattccgg ttcgcctgtc
    22381 gggtgaagac tccggtcgcg gtaccttctt ccaccgccac gcggtgatcc acaaccagtc
    22441 taacggttcc acttacacgc cgctgcaaca tatccataac gggcagggcg cgttccgtgt
    22501 ctgggactcc gtactgtctg aagaagcagt gctggcgttt gaatatggtt atgccaccgc
    22561 agaaccacgc actctgacca tctgggaagc gcagttcggt gacttcgcca acggtgcgca
    22621 ggtggttatc gaccagttca tctcctctgg cgaacagaaa tggggccgga tgtgtggtct
    22681 ggtgatgttg ctgccgcacg gttacgaagg gcaggggccg gagcactcct ccgcgcgtct
    22741 ggaacgttat ctgcaacttt gtgctgagca aaacatgcag gtttgcgtac cgtctacccc
    22801 ggcacaggtt taccacatgc tgcgtcgtca ggcgctgcgc gggatgcgtc gtccgctggt
    22861 cgtgatgtcg ccgaaatccc tgctgcgtca tccgctggcg gtttccagcc tcgaagaact
    22921 ggcgaacggc accttcctgc cagccatcgg tgaaatcgac gagcttgatc cgaagggcgt
    22981 gaagcgcgta gtgatgtgtt ctggtaaggt ttattacgac ctgctggaac agcgtcgtaa
    23041 gaacaatcaa cacgatgtcg ccattgtgcg tatcgagcaa ctctacccgt tcccgcataa
    23101 agcgatgcag gaagtgttgc agcagtttgc tcacgtcaag gattttgtct ggtgccagga
    23161 agagccgctc aaccagggcg catggtactg cagccagcat catttccgtg aagtgattcc
    23221 gtttggggct tctctgcgtt atgcaggccg cccggcctcc gcctctccgg cggtagggta
    23281 tatgtccgtt caccagaaac agcaacaaga tctggttaat gacgcgctga acgtcgaata
    23341 aataaaggat acacaatgag tagcgtagat attctggtcc ctgacctgcc tgaatccgta
    23401 gccgatgcca ccgtcgcaac ctggcataaa aaacccggcg acgcagtcgt acgtgatgaa
    23461 gtgctggtag aaatcgaaac tgacaaagtg gtactggaag taccggcatc agcagacggc
    23521 attctggatg cggttctgga agatgaaggt acaacggtaa cgtctcgtca gatccttggt
    23581 cgcctgcgtg aaggcaacag cgccggtaaa gaaaccagcg ccaaatctga agagaaagcg
    23641 tccactccgg cgcaacgcca gcaggcgtct ctggaagagc aaaacaacga tgcgttaagc
    23701 ccggcgatcc gtcgcctgct ggctgaacac aatctcgacg ccagcgccat taaaggcacc
    23761 ggtgtgggtg gtcgtctgac tcgtgaagat gtggaaaaac atctggcgaa agccccggcg
    23821 aaagagtctg ctccggcagc ggctgctccg gcggcgcaac cggctctggc tgcacgtagt
    23881 gaaaaacgtg tcccgatgac tcgcctgcgt aagcgtgtgg cagagcgtct gctggaagcg
    23941 aaaaactcca ccgccatgct gaccacgttc aacgaagtca acatgaagcc gattatggat
    24001 ctgcgtaagc agtacggtga agcgtttgaa aaacgccacg gcatccgtct gggctttatg
    24061 tccttctacg tgaaagcggt ggttgaagcc ctgaaacgtt acccggaagt gaacgcttct
    24121 atcgacggcg atgacgtggt ttaccacaac tatttcgacg tcagcatggc ggtttctacg
    24181 ccgcgcggcc tggtgacgcc ggttctgcgt gatgtcgata ccctcggcat ggcagacatc
    24241 gagaagaaaa tcaaagagct ggcagtcaaa ggccgtgacg gcaagctgac cgttgaagat
    24301 ctgaccggtg gtaacttcac catcaccaac ggtggtgtgt tcggttccct gatgtctacg
    24361 ccgatcatca acccgccgca gagcgcaatt ctgggtatgc acgctatcaa agatcgtccg
    24421 atggcggtga atggtcaggt tgagatcctg ccgatgatgt acctggcgct gtcctacgat
    24481 caccgtctga tcgatggtcg cgaatccgtg ggcttcctgg taacgatcaa agagttgctg
    24541 gaagatccga cgcgtctgct gctggacgtg tagtagttta agtttcacct gcactgtaga
    24601 ccggataagg cattatcgcc ttctccggca attgaagcct gatgcgacgc tgacgcgtct
    24661 tatcaggcct acgggaccac caatgtaggt cggataaggc gctagcgccg catccgacaa
    24721 gcgatgcctg atgtgacggt taacgtgtct tatcaggcct acggggacca ccaatgtagg
    24781 tcggataagg cgcaagcgcc gcatccgaca agcgatgcct gatgtgacgt ttaacgtgtc
    24841 ttatcaggcc tatgggtgac cgacaatgcc cggaagcgat acgaaatatt cggtctacgg
    24901 tttaaaagat aacgattact gaaggatgga cagaacacat gaacttacat gaatatcagg
    24961 caaaacaact ttttgcccgc tatggcttac cagcaccggt gggttatgcc tgtactactc
    25021 cgcgcgaagc agaagaagcc gcttcaaaaa tcggtgccgg tccgtgggta gtgaaatgtc
    25081 aggttcacgc tggtggccgc ggtaaagcgg gcggtgtgaa agttgtaaac agcaaagaag
    25141 acatccgtgc ttttgcagaa aactggctgg gcaagcgtct ggtaacgtat caaacagatg
    25201 ccaatggcca accggttaac cagattctgg ttgaagcagc gaccgatatc gctaaagagc
    25261 tgtatctcgg tgccgttgtt gaccgtagtt cccgtcgtgt ggtctttatg gcctccaccg
    25321 aaggcggcgt ggaaatcgaa aaagtggcgg aagaaactcc gcacctgatc cataaagttg
    25381 cgcttgatcc gctgactggc ccgatgccgt atcagggacg cgagctggcg ttcaaactgg
    25441 gtctggaagg taaactggtt cagcagttca ccaaaatctt catgggcctg gcgaccattt
    25501 tcctggagcg cgacctggcg ttgatcgaaa tcaacccgct ggtcatcacc aaacagggcg
    25561 atctgatttg cctcgacggc aaactgggcg ctgacggcaa cgcactgttc cgccagcctg
    25621 atctgcgcga aatgcgtgac cagtcgcagg aagatccgcg tgaagcacag gctgcacagt
    25681 gggaactgaa ctacgttgcg ctggacggta acatcggttg tatggttaac ggcgcaggtc
    25741 tggcgatggg tacgatggac atcgttaaac tgcacggcgg cgaaccggct aacttccttg
    25801 acgttggcgg cggcgcaacc aaagaacgtg taaccgaagc gttcaaaatc atcctctctg
    25861 acgacaaagt gaaagccgtt ctggttaaca tcttcggcgg tatcgttcgt tgcgacctga
    25921 tcgctgacgg tatcatcggc gcggtagcag aagtgggtgt taacgtaccg gtcgtggtac
    25981 gtctggaagg taacaacgcc gaactcggcg cgaagaaact ggctgacagc ggcctgaata
    26041 ttattgcagc aaaaggtctg acggatgcag ctcagcaggt tgttgccgca gtggagggga
    26101 aataatgtcc attttaatcg ataaaaacac caaggttatc tgccagggct ttaccggtag
    26161 ccaggggact ttccactcag aacaggccat tgcatacggc actaaaatgg ttggcggcgt
    26221 aaccccaggt aaaggcggca ccacccacct cggcctgccg gtgttcaaca ccgtgcgtga
    26281 agccgttgct gccactggcg ctaccgcttc tgttatctac gtaccagcac cgttctgcaa
    26341 agactccatt ctggaagcca tcgacgcagg catcaaactg attatcacca tcactgaagg
    26401 catcccgacg ctggatatgc tgaccgtgaa agtgaagctg gatgaagcag gcgttcgtat
    26461 gatcggcccg aactgcccag gcgttatcac tccgggtgaa tgcaaaatcg gtatccagcc
    26521 tggtcacatt cacaaaccgg gtaaagtggg tatcgtttcc cgttccggta cactgaccta
    26581 tgaagcggtt aaacagacca cggattacgg tttcggtcag tcgacctgtg tcggtatcgg
    26641 cggtgacccg atcccgggct ctaactttat cgacattctc gaaatgttcg aaaaagatcc
    26701 gcagaccgaa gcgatcgtga tgatcggtga gatcggcggt agcgctgaag aagaagcagc
    26761 tgcgtacatc aaagagcacg ttaccaagcc agttgtgggt tacatcgctg gtgtgactgc
    26821 gccgaaaggc aaacgtatgg gccacgcggg tgccatcatt gccggtggga aagggactgc
    26881 ggatgagaaa ttcgctgctc tggaagccgc aggcgtgaaa accgttcgca gcctggcgga
    26941 tatcggtgaa gcactgaaaa ctgttctgaa ataaatatct gtaataagaa atagccctcg
    27001 ccgcttccct ctacaggaat ggcgaagggc tgtcggtttc gacatggttg gccatcgtat
    27061 gatggccttt tttgtgctta tcgcgatgat tttcgctgcg ctatcagggt aaatttatag
    27121 tcatcggtat taaaagcgtt gcggctatat tcaaacaccc gaccatcaac taaatatcca
    27181 cgcgatactt tttcaagaat cggctttgtc tggctgatat taagcagacg gctcatctct
    27241 tcggttggca tcagaggaat gatttcctgt tcgctacgat cgataaccat tttcttcact
    27301 tcttcgataa agtgatattt cgaattttcc atgacctgcc aggtgagatc cgggaacaac
    27361 gcaagcggca tccaggtttc ttccagcgcc attggctttt gcttgcgata gcgcacgcgc
    27421 ttcacatgcc acacacgatc ctgcggggtg atttgtagct gttgctgaag aaaatcgtca
    27481 gccggaatca cttcgaatat cagaacttca ctgtgtgtat cgacgtgacg gtccgacagt
    27541 ttttcatcaa aactggttaa ctgaaaaata tcgtaattga cccgctcttc tttgacgtaa
    27601 gtcccgctgc cctgaatgct ttcgaggatc tgctgctcga ctagctggcg caaagcctga
    27661 cgcaccgtaa cccggctgac gccaaactct gtttgtagcg ctgattcagt gggtaacgca
    27721 tcgccaggtt taagctcgcc acgcgcaatt tgttcacgaa tgcgatcggc aatctgccgg
    27781 tataagggct tgtgtcccat ttttagtatc tcattaatac gaatttaacc attatgcccg
    27841 ataaattcat cctgtaaata atacaaacac aatacaaata atttcaatca agtgaaattg
    27901 atcacataat ggtattgttt tatcgggcac actggcgcga ctataaaaac gatcaagtga
    27961 ggatcatgat gaatctgacg actctgaccc accgcgatgc gttgtgtctg aatgcgcgct
    28021 ttaccagccg tgaagaggcc atccacgcgt tgactcaacg tcttgctgct ctggggaaaa
    28081 tttccagtac tgagcaattt ctggaagaag tgtatcgccg tgaaagcctt ggcccgaccg
    28141 ccttaggtga agggttggct gtgccgcatg gcaaaactgc tgcggtaaaa gaagcggcgt
    28201 ttgcggtcgc cacactcagc gagccgcttc agtgggaagg cgttgatggc ccggaagcag
    28261 ttgatttagt ggtgctgctg gcgattcccc ccaatgaagc gggtactacg catatgcaac
    28321 tgctgacagc gctgaccacg cgccttgcgg atgatgagat tcgggcgcgt atacagtcgg
    28381 cgacgacgcc tgatgagttg ctctcggcgc tggatgacaa gggaggcacg caaccttctg
    28441 cctctttttc caacgcgcca actatcgtct gcgtaacggc ctgtccggcg ggtattgctc
    28501 acacctatat ggctgcggaa tatctggaaa aagccggacg caaactcggc gtaaatgttt
    28561 acgttgaaaa acaaggcgct aacggcattg aagggcgttt aacggcggat caactcaata
    28621 gtgcaaccgc ctgtattttt gcggctgaag tcgccatcaa ggagagtgag cgttttaatg
    28681 gcattcccgc gctttcagtg cctgttgccg agccgattcg ccatgcagaa gcgttgatcc
    28741 aacaagcgct taccctcaag cgtagcgatg agacgcgtac cgtacagcaa gatacgcaac
    28801 cggtgaaaag tgtcaaaacg gagctgaaac aggcactgtt gagcggaatc tcttttgccg
    28861 taccgttgat tgtcgcgggg ggcacggtgc tggcggtcgc ggtattactg tcgcaaatct
    28921 tcgggctaca agatctgttt aatgaagaaa actcctggct gtggatgtac cgcaagctgg
    28981 gcggcgggct gctcggaatt ttgatggtac cggtgctcgc ggcctatacc gcctattctc
    29041 tggcagataa accggcgtta gcgccaggct ttgcggctgg acttgccgcc aacatgatcg
    29101 gctccgggtt tctcggcgcg gtcgttggcg gattgatagc cggttacttg atgcgctggg
    29161 tgaaaaatca cttgcgtctt agcagtaaat tcaatggatt cctgactttt tatctctacc
    29221 cggtgctcgg tacgttggga gcgggcagtc tgatgctgtt tgtggtgggg gaacctgtcg
    29281 cctggatcaa taactcgctt accgcctggc tgaacggtct gtcaggaagt aacgcgctgt
    29341 tgctgggtgc cattctcggt tttatgtgtt cctttgacct tggagggcca gtgaataaag
    29401 ccgcttatgc attctgcctg ggcgcaatgg cgaacggcgt ttacggcccg tatgccattt
    29461 tcgcctccgt caaaatggtt tcggcattta ccgtaaccgc ttccacgatg ctcgcaccgc
    29521 gcctgtttaa agagtttgaa attgagaccg ggaaatccac ctggctgtta gggctggcag
    29581 gtattaccga aggggcgatc ccgatggcga ttgaagatcc gctgcgggtt attggttcgt
    29641 ttgtgctggg ctctatggta acgggcgcta ttgtcggtgc gatgaatatc ggcctttcga
    29701 cacccggtgc cggcattttc tcgctctttt tacttcatga taatggcgcg ggcggtgtta
    29761 tggcggcaat tggctggttt ggcgcggcat tggtgggggc tgcaatctcg actgcaattc
    29821 tcctgatgtg gcggcgtcac gcggttaagc atggcaacta tctgactgat ggcgtaatgc
    29881 cataaacaaa aaggaaacga cgatgaaagc agtatctcgc gttcacatca ccccgcatat
    29941 gcactgggat cgagagtggt atttcaccac cgaagagtca cgtattctgc tggtcaataa
    30001 tatggaagag atcctgtgcc gactggaaca ggacaacgaa tacaaatatt acgtactcga
    30061 cgggcaaacg gcgatcctcg aagattattt cgcggtgaaa ccggaaaaca aagaccgtgt
    30121 gaagaaacag gtagaagccg gcaagttgat tatcggcccc tggtataccc agaccgatac
    30181 cacgattgtt tctgcggaat ccatcgtccg taatctgatg tacggaatgc gtgactgcct
    30241 cgcgtttggc gagccgatga aaataggtta tttaccagat tcctttggca tgtccgggca
    30301 actgccgcat atctacaatg gatttggcat tacccgcacc atgttctggc gcggatgttc
    30361 ggagcgccac ggtactgata aaaccgagtt tttgtggcaa agcagtgacg gtagcgaagt
    30421 gacggcgcag gtgctgccgc tgggctacgc catcggtaag tacttacctg ccgacgaaaa
    30481 cggattacgt aaacgcctcg acagttattt tgacgtgctg gaaaaagcgt ctgtaaccaa
    30541 agagattttg ctgccgaatg ggcatgacca gatgccattg cagcaaaata tcttcgaagt
    30601 gatggataag ctacgtgaga tctaccctca acgtaagttt gtgatgagcc gctttgaaga
    30661 ggtatttgag aagatcgaag cgcagcgaga taatctggca accctgaaag gggaatttat
    30721 tgatggcaaa tatatgcgcg tgcatcgcac catcggttct acgcgtatgg atatcaaaat
    30781 tgcccacgcg cgtattgaaa ataagattgt taatctgctg gaaccgctgg caacactggc
    30841 ctggacgttg ggttttgaat accaccacgg cttgctggag aaaatgtgga aagagatctt
    30901 aaaaaatcat gcccacgaca gtatcggctg ctgctgtagt gacaaagttc atcgcgaaat
    30961 cgtcgcccgc ttcgaactgg ctgaagacat ggcggataat ctgattcgtt tctacatgcg
    31021 caaaattgcc gacaacatgc cgcagagcga cgccgacaaa ctcgtcctgt ttaacctgat
    31081 gccctggccg cgtgaagaag ttatcaacac cactgtgcgg ctgcgcgcca gccagtttaa
    31141 tttgcgggac gatcgcggtc agcctgtacc gtattttatt cgccatgccc gtgagatcga
    31201 tccaggccta atcgatcggc aaatagttca ttacggtaat tacgatccct ttatggagtt
    31261 tgatatacag atcaaccaga ttgtcccttc tatgggctat cgcacgcttt atatcgaagc
    31321 gaatcagcct ggcaacgtaa ttgcggcaaa aagtgacgct gaagggatac tggaaaatgc
    31381 tttctggcaa attgcgctca atgaggatgg ttctctgcaa ctggtagata aagacagcgg
    31441 tgtgcgctat gaccgggtat tgcaaattga agaaagctct gatgatggtg atgaatatga
    31501 ctattcaccc gcaaaagaag agtgggtaat taccgcagcg aacgcgaaac cgcaatgcga
    31561 tattattcat gaagcctggc agagcagggc tgttatccgc tatgacatgg cagtgccgct
    31621 caatttgtca gaacgcagcg cccggcaatc cactggcaga gtaggggtgg tgttggttgt
    31681 cactcttagt cataacagca ggcgtattga tgtggatatc aatcttgata accaggctga
    31741 cgatcatcgc cttcgtgtcc tggtccctac accttttaac accgacagtg ttctggcaga
    31801 tacgcagttt ggttcgctaa cgcgccccgt gaacgacagt gcaatgaaca actggcagca
    31861 agaaggctgg aaagaagcgc cggttccggt atggaatatg ctcaactatg ttgccttaca
    31921 ggaagggcgt aacggcatgg ctgtctttag cgaagggtta cgtgaatttg aagtcatcgg
    31981 tgaagagaag aaaacctttg ccattacgtt gctgcgtggc gtgggcttac tgggcaaaga
    32041 agatctgctt ttaaggcctg ggcggccttc gggaattaaa atgccagtcc cggactcaca
    32101 actacgtggt ctgctttctt gtcgcctaag tttattgagt tataccggta cgccaaccgc
    32161 cgctggtgta gctcagcagg cgcgagcatg gctgactcca gtacagtgtt acaacaaaat
    32221 cccatgggat gtgatgaagc tcaacaaagc cggattcaac gtgccggaaa gttatagttt
    32281 gttgaaaatg cccccagtgg gatgcctgat aagcgcactt aagaaagctg aagaccgaca
    32341 agaagtgatt ttacggctgt ttaatccggc tgaatcagca acctgtgatg cgactgttgc
    32401 tttcagtcgc gaggtgattt cttgctcaga aacgatgatg gatgaacaca ttaccaccga
    32461 ggaaaatcaa ggttcaaatc tatcggggcc ttttttaccc ggccagtcac ggacgttcag
    32521 ttaccggctt gcctgaatag caatcaaacc gaagccacat atgcgcggcc agattgttga
    32581 caaagggcgc tttgttcatg ccggatacgg catgaacgct ttattcggtc tacaaaagca
    32641 ggcaaattca atatattgca gagatgatgt agacactggc aagcgtagcg catcaggtaa
    32701 ttttgcgttt atcttcactc tcaagccacg tatatgtggc tttattttta acaaaataat
    32761 aaccctgggt gagttaatta taatataatt ataagttaac taaatgttaa tattggcggg
    32821 gtggatttat gcctttatta gtaatcctga aactctgcgt cgtattagcc agtgaccaaa
    32881 aaaagaatta aggtcaaccg tgctgttttt gcttcgtctc tttttatctt taattgccaa
    32941 ccgaaactaa tttcagcctt ataactcaca cattttaaac ataaatgtca ctaaagttac
    33001 cttattgaaa catgattaac ataatttgta gga
//
LOCUS       DACAOP010000046        32555 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.046, whole genome shotgun sequence.
ACCESSION   DACAOP010000046 DACAOP010000000
VERSION     DACAOP010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32555
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.046"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            56..484
                     /locus_tag="IT892_002420"
     CDS             56..484
                     /locus_tag="IT892_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001751700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rhsA"
                     /protein_id="HAP3135628.1"
                     /translation="MNPVTNTDPLGLEVFPRPFPLPIPWPKSPAQQQADDNAAKALTK
                     WWNDTASQRIFDSLILNNPGLALDITMIASRGNVADTGITDRVNDIINDRFWSDGKKP
                     DRCDVLQELIDCGDISAKDAKSTQKAWNCRHSRQSNDKKR"
     gene            505..1347
                     /locus_tag="IT892_002421"
     CDS             505..1347
                     /locus_tag="IT892_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lyase"
                     /protein_id="HAP3135629.1"
                     /translation="MSNTYQKRKASKEYGLYNQCKKLNDDELFRLLDDHNSLKRISSA
                     RVLQLRGGQDAVRLAIEFCSDKNYIRRDIGAFILGQIKICKKCEDNVFNILNNMALND
                     KSACVRATAIESTAQRCKKNPIYSPKIVEQSQITAFDKSTNVRRATAFAISVINDKAT
                     IPLLINLLKDPNGDVRNWAAFAININKYDNSDIRDCFVEMLQDKNEEVRIEAIIGLSY
                     RKDKRVLSVLCDELKKNTVYDDIIEAAGELGDKTLLPVLDTMLYKFDDNEIITSAIDK
                     LKRS"
     gene            1500..2333
                     /locus_tag="IT892_002422"
     CDS             1500..2333
                     /locus_tag="IT892_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001359919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HAP3135630.1"
                     /translation="MDPVYTPARKIHLYHCDHRGLPLALISTEGATAWCAEYDEWGNL
                     LSDENPHHLQQLIRLPGQQYDEESGLYYNRHRYYDPLLGRYITQDPIGLKGGWNFYQY
                     PLNPVINVDPQGLVDINLYPESDLIHSVADEINIPGVFTIGGHGTPTSIESATRSIMT
                     AKDLAYLIKFDGNYKDGMTVWLFSCNTGKGQNSFASQLAKELHTNVIGPDTLWTWWGR
                     GTNGKLKMDTVLTAPTNLNSNKDLMAITTKDLGNWITYGPSGHPISNMQGTPEKPSDI
                     R"
     gene            2345..2806
                     /locus_tag="IT892_002423"
     CDS             2345..2806
                     /locus_tag="IT892_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HAP3135631.1"
                     /translation="MKACLLLFFYFSFICQLHGADVKIKQNESMMGSTAMTYDLSEEK
                     LMKLKYKSQHGDSEASFRLYQYYCFTKNNIYKQLRFLERSASQGNVTAQFNYGVFLSD
                     TNPTLSEYYNLNRAIYWMEFAVNNGNIDAKSKLQELKKLKRMDRRKNKENP"
     gene            3513..3848
                     /locus_tag="IT892_002424"
     CDS             3513..3848
                     /locus_tag="IT892_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135632.1"
                     /translation="MADKAILWALISASTKEGRKACSLSYFACKAAEAELGLAYMAAN
                     DNKEFLTSLSNIMRYKIDAGLSESYTCYLLSKGKIIRPYLKNLNPLQLAADCIETVNK
                     IKDKNKKNH"
     gene            complement(4411..5547)
                     /locus_tag="IT892_002425"
     CDS             complement(4411..5547)
                     /locus_tag="IT892_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAP3135633.1"
                     /translation="MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLI
                     LLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVRYQAR
                     VDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFS
                     ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLE
                     QTVIRAPSNGYVTQVLIRPGTYAAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGD
                     DAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPGTDGVLGTIELDPND
                     DIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH"
     gene            complement(5550..5912)
                     /locus_tag="IT892_002426"
     CDS             complement(5550..5912)
                     /locus_tag="IT892_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HAP3135634.1"
                     /translation="MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAI
                     HTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSHVASQEKATDPEIAALSDRISRL
                     EHQLAAEKKTDYSTFPEI"
     gene            6449..8362
                     /locus_tag="IT892_002427"
     CDS             6449..8362
                     /locus_tag="IT892_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAP3135635.1"
                     /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP
                     NETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADMPMFLGSMI
                     AGPLGGWCIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPIVEALSKM
                     LAAGVNFMVVHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIE
                     ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG
                     GMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAYFANIAGVCAAMAVSFVVSAILL
                     KTSKVKEEDDIEAATRRMQDMKAESKGASPLSAGDVTNDLSHVRKIIVACDAGMGSSA
                     MGAGVLRKKIQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT
                     NFLDSGLYTSLTERLVAAQRHTANEEKVKDSLKDSFDDSSANLFKLGAENIFLGRKAA
                     TKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT
                     GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTT
                     SVDEVLELLAGRK"
     gene            8592..9740
                     /gene="mtlD"
                     /locus_tag="IT892_002428"
     CDS             8592..9740
                     /gene="mtlD"
                     /locus_tag="IT892_002428"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAP3135636.1"
                     /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH
                     SYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKG
                     LVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRI
                     VPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNT
                     GHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQK
                     ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHF
                     RSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ"
     gene            9740..10327
                     /gene="mtlR"
                     /locus_tag="IT892_002429"
     CDS             9740..10327
                     /gene="mtlR"
                     /locus_tag="IT892_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor MtlR"
                     /protein_id="HAP3135637.1"
                     /translation="MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRS
                     FLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVI
                     NRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
                     YAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK"
     gene            complement(10339..10548)
                     /locus_tag="IT892_002430"
     CDS             complement(10339..10548)
                     /locus_tag="IT892_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135638.1"
                     /translation="MGKLGENVPLLIDKAVDFMASSQAFREYLKKLPPRNAIPSGIPD
                     ESVPLYLQRLEYYRRLYRPKQVEGQ"
     gene            10833..11195
                     /locus_tag="IT892_002431"
     CDS             10833..11195
                     /locus_tag="IT892_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibL family ribosome-associated protein"
                     /protein_id="HAP3135639.1"
                     /translation="MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKAT
                     LEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKEQADMGKLKKSVRGLVVVHPMTA
                     LGREMGLQEMTGFSKTAF"
     gene            11567..13222
                     /gene="lldP"
                     /locus_tag="IT892_002432"
     CDS             11567..13222
                     /gene="lldP"
                     /locus_tag="IT892_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HAP3135640.1"
                     /translation="MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAAS
                     WTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDI
                     IRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLC
                     LIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWR
                     GIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFR
                     FGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFASGGALYEW
                     VINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPS
                     DAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLG
                     WLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIAC
                     AAVGLVGKESDLFRFTVKHSLIFTCIVGVITTLQAYVLTWMIP"
     gene            13222..13998
                     /gene="lldR"
                     /locus_tag="IT892_002433"
     CDS             13222..13998
                     /gene="lldR"
                     /locus_tag="IT892_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LldR"
                     /protein_id="HAP3135641.1"
                     /translation="MIVLPRRLSDEVADRVRALIDEKNLEAGMKLPAERQLAMQLGVS
                     RNSLREALAKLVSEGVLLSRRGGGTFIRWRHDTWSEQNIVQPLKTLMADDPDYSFDIL
                     EARYAIEASTAWHAAMRATPGDKEKIQLCFEATLSEDPDIASQADVRFHLAIAEASHN
                     IVLLQTMRGFFDVLQSSVKHSRQRMYLVPPVFSQLTEQHQAVIDAIFAGDADGARKAM
                     MAHLSFVHTTMKRFDEDQARHARITRLPGEHNEHSREKNA"
     gene            13995..15185
                     /gene="lldD"
                     /locus_tag="IT892_002434"
     CDS             13995..15185
                     /gene="lldD"
                     /locus_tag="IT892_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent L-lactate dehydrogenase"
                     /protein_id="HAP3135642.1"
                     /translation="MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSE
                     VALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIP
                     FTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
                     PGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLE
                     DYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHG
                     GRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLY
                     ALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAK
                     GNAA"
     gene            15383..15856
                     /gene="trmL"
                     /locus_tag="IT892_002435"
     CDS             15383..15856
                     /gene="trmL"
                     /locus_tag="IT892_002435"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAP3135643.1"
                     /translation="MLNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRL
                     RRAGLDYHEFTAVTRHHDYRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPE
                     TRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGAVLRD"
     gene            complement(15909..16730)
                     /gene="cysE"
                     /locus_tag="IT892_002436"
     CDS             complement(15909..16730)
                     /gene="cysE"
                     /locus_tag="IT892_002436"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAP3135644.1"
                     /translation="MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSA
                     LSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
                     LYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHAT
                     GIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGA
                     KIGAGSVVLQPVPPHTTAAGVPARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI"
     gene            complement(16810..17829)
                     /gene="gpsA"
                     /locus_tag="IT892_002437"
     CDS             complement(16810..17829)
                     /gene="gpsA"
                     /locus_tag="IT892_002437"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP3135645.1"
                     /translation="MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATL
                     ERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPD
                     ARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
                     QTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTAL
                     ITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSA
                     QEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKD
                     ERSSH"
     gene            complement(17829..18296)
                     /gene="secB"
                     /locus_tag="IT892_002438"
     CDS             complement(17829..18296)
                     /gene="secB"
                     /locus_tag="IT892_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HAP3135646.1"
                     /translation="MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDL
                     DTASTQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYC
                     PNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA"
     gene            complement(18359..18610)
                     /gene="grxC"
                     /locus_tag="IT892_002439"
     CDS             complement(18359..18610)
                     /gene="grxC"
                     /locus_tag="IT892_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HAP3135647.1"
                     /translation="MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEM
                     IKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLK"
     gene            complement(18752..19183)
                     /locus_tag="IT892_002440"
     CDS             complement(18752..19183)
                     /locus_tag="IT892_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP3135648.1"
                     /translation="MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVITRGE
                     ATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDG
                     SGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK"
     gene            19428..20972
                     /gene="gpmM"
                     /locus_tag="IT892_002441"
                     /gene_synonym="pgmI"
     CDS             19428..20972
                     /gene="gpmM"
                     /locus_tag="IT892_002441"
                     /gene_synonym="pgmI"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HAP3135649.1"
                     /translation="MSVSKKPMVLVILDGYGYREEQQDNAIFSAKTPVMDALWANRPH
                     TLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKDRAFFANPVLTGA
                     VDKAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
                     SAESSLKKFEEKFAALGKGRVASIIGRYYAMDRDNRWDRVEKAYDLLTLAQGEFQADT
                     AVAGLQAAYARDENDEFVKATVIRAEGQPDAAMEDGDALIFMNFRADRAREITRAFVN
                     ADFDGFARKKVVNVDFVMLTEYAADIKTAVAYPPASLVNTFGEWMAKNDKTQLRISET
                     EKYAHVTFFFNGGVEESFKGEDRILINSPKVATYDLQPEMSSAELTEKLVAAIKSGKY
                     DTIICNYPNGDMVGHTGVMEAAVKAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQ
                     MRDPATGQAHTAHTNLPVPLIYVGDKNVKAVAGGKLSDIAPTMLSLMGMEIPQEMTGK
                     PLFIVE"
     gene            20982..22265
                     /gene="envC"
                     /locus_tag="IT892_002442"
     CDS             20982..22265
                     /gene="envC"
                     /locus_tag="IT892_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC"
                     /protein_id="HAP3135650.1"
                     /translation="MRGKAINTMTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADE
                     RDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNK
                     QIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYF
                     GYLNQARQETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALNERKK
                     TLAGLESSIQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEA
                     TRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRWKGMVIG
                     ASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQ
                     PIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR"
     gene            22269..23228
                     /locus_tag="IT892_002443"
     CDS             22269..23228
                     /locus_tag="IT892_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent polysaccharide deacetylase family
                     protein"
                     /protein_id="HAP3135651.1"
                     /translation="MFPFRRNVLAFAALLALSSPVLAGKLAIVIDDFGYRPHNENQVL
                     AMPSAISVAVLPDSPHAREMATKAHNSGHEVLIHLPMAPLSKQPLEKNTLRPEMSSDE
                     IERIIRSAVNNVPYAVGINNHMGSKMTSNLFGMQKVMQALERYNLYFLDSVTIGNTQA
                     MRAAQGTGVKVIKRKVFLDDSQNEADIRVQFNRAIDLARRNGSTIAIGHPHPSTVRVL
                     QQMVYNLPPDITLVKASSLLNEPQVDTSTPPKNAVPDAPRNPFRGVKLCKPKKPIEPV
                     YANRFFEVLSESISQSTLIVYFQHQWQGWGKQPEAAKFNASAN"
     gene            complement(23215..24249)
                     /gene="waaH"
                     /locus_tag="IT892_002444"
     CDS             complement(23215..24249)
                     /gene="waaH"
                     /locus_tag="IT892_002444"
                     /EC_number="2.4.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate:LPS(HepIII) glycosyltransferase"
                     /protein_id="HAP3135652.1"
                     /translation="MMNSTNKLSVIIPLYNAGDDFRTCMESLITQTWTALEIIIINDG
                     STDNSVEIAKHYAENYPHVRLLHQANAGASVARNRGIEVATGKYVAFVDADDEVYPTM
                     YETLMTMALEDDLDVAQCNADWCFRETGETWQSIPTDRLRSTGVLTGPDWLRMGLSSR
                     RWTHVVWMGVYRRDVIVKNNIKFIAGLHHQDIVWTTEFMFNALRARYTEQSLYKYYLH
                     NTSVSRLHRQGNKNLNYQRHYIKITRLLEKLNRNYADKIMIYPEFHQQITYEALRVCH
                     AVRKEPDILTRQRMIAEIFTSGMYKRLITNVRSVKVGYQALLWSFRLWQWRDKTRSHH
                     RITRSAFNLR"
     gene            complement(24488..25513)
                     /gene="tdh"
                     /locus_tag="IT892_002445"
     CDS             complement(24488..25513)
                     /gene="tdh"
                     /locus_tag="IT892_002445"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAP3135653.1"
                     /translation="MKALSKLKAEEGIWMTDVPEPELGHNDLLIKIRKTAICGTDVHI
                     YNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGG
                     RTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSF
                     DLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKE
                     NLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKV
                     IFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSG
                     KVILSWD"
     gene            complement(25523..26719)
                     /gene="kbl"
                     /locus_tag="IT892_002446"
     CDS             complement(25523..26719)
                     /gene="kbl"
                     /locus_tag="IT892_002446"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAP3135654.1"
                     /translation="MRGDFYQQLANDLETARAEGLFKEERIITSAQQADITVADGSHV
                     INFCANNYLGLANHPELIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGM
                     EDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMQE
                     LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCNLADKYDALVMVDDSHAVGFV
                     GENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNS
                     LAPAIVAASIKVLEMVEAGSELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGD
                     AVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTSEQITRAVEAFTRIGK
                     QLGVIA"
     gene            26933..27913
                     /gene="rfaD"
                     /locus_tag="IT892_002447"
     CDS             26933..27913
                     /gene="rfaD"
                     /locus_tag="IT892_002447"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HAP3135655.1"
                     /translation="MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD
                     LNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLH
                     YCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
                     QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA
                     DVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFT
                     QADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDINVNSQNHSSGIKAATK"
     gene            27993..29039
                     /gene="rfaF"
                     /locus_tag="IT892_002448"
     CDS             27993..29039
                     /gene="rfaF"
                     /locus_tag="IT892_002448"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose--LPS heptosyltransferase RfaF"
                     /protein_id="HAP3135656.1"
                     /translation="MKILVIGPSWVGDMMMSQSLYRTLQARYPQAIIDVMAPAWCRPL
                     LSRMPEVNEAIPMPLGHGALEIGERRKLGHSLREKRYDRAYVLPNSFKSALVPFFAGI
                     PHRTGWRGEMRYGLLNDVRVLDKEAWPLMVERYVALAYDKGIMRTAQDLPQPLLWPQL
                     QVSEGEKSYTCNQFSLSSERPMIGFCPGAEFGPAKRWPHYHYAELAKQLIDEGYQVVL
                     FGSAKDHEAGNEILAALNTEQQAWCRNLAGETQLDQAVILIAACKAIVTNDSGLMHVA
                     AALNRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDAAEGYHQSLIDITPQR
                     VLEELNSLLLQEEA"
     gene            29043..29999
                     /gene="rfaC"
                     /locus_tag="IT892_002449"
     CDS             29043..29999
                     /gene="rfaC"
                     /locus_tag="IT892_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase RfaC"
                     /protein_id="HAP3135657.1"
                     /translation="MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQI
                     PSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAAL
                     VTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERIRELFAKSLGYSKPQTQ
                     GDYAIAQHFLTNLPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWG
                     APHEEKRAKRLAEGFAYVEVLPKMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNI
                     TVYGPTDPGLIGGYGKNQVVCRAPDKDLAHLTAETVFNKINS"
     gene            30038..31255
                     /gene="rfaL"
                     /locus_tag="IT892_002450"
     CDS             30038..31255
                     /gene="rfaL"
                     /locus_tag="IT892_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase RfaL"
                     /protein_id="HAP3135658.1"
                     /translation="MLTASLALRNKEKWKPYWNKALVFLFIATFFLDGITRYKHIISI
                     LMIITVIYQVSRAPGTFKVLYKNNLFYSVLALSLILLYATFISPDLKISFKEFSNTVL
                     KGFLAYSLLIPALLKDEDNESIGKIVLYSLVTGLGLRCLVELILYIQDYNKGIIPFST
                     YEHRSISDSMVFLFPALLNLWLIKKTSYKIAFVIFSAVFLFLLLGTLSRGAWLAVFIV
                     TLLWLILNRQWKLLMLTSIVISVAAVGVFTYKGDHAGKDRLIYKLQQTDSSSRYTNGT
                     QGTAWTLIMENPLKGYGYGDDIYHAIYNKRVVDFPSWKFRQSIGPHNVVLSIWFAAGL
                     AGLLALLYLYGSIIKETANATFKTVVVTPYNGQLLLFLTLVSFYIIRGNFEEVDLKPI
                     GLIVGLLLAMRNK"
     gene            complement(31309..32451)
                     /locus_tag="IT892_002451"
     CDS             complement(31309..32451)
                     /locus_tag="IT892_002451"
                     /EC_number="2.4.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylglucosaminyltransferase"
                     /protein_id="HAP3135659.1"
                     /translation="MIKKIIFTVTPIFSIPPKGAAAVETWIYQVAKRLSIPVTIACIR
                     NEGYPTYTKVNDHCDIHYIGFSRVYKRLFQKWTRLDPVPYSQRILNTQPKNTDPKDSV
                     IVIHNSMKLYKQIRSRSPHAQLVMHLHNAFEPGELDKNAKIIVPSQFLFDFYSEKMPD
                     ANIAIVPNGFCSESYEQNNTEDLRQKLNIDANDTVLLFAGRISPDKGCLMLMEAFNQL
                     NKIQDNLKLVIVGDPFASKKGEKAEYQKKVLDAAKAIGAQCIMAGGQPPEQMHNYYRL
                     ADLVVVPSQVEEAFCMVAVEAMAAGKPVLASQKGGISEFVLEGITGYHLAEPMTSESI
                     LADIKRVLADADRAQIAKNARNFVFSKYSWEHVTQRFEAQIQDWFG"
BASE COUNT         8468 a         7962 c         8065 g         8060 t
ORIGIN      
        1 tatcactcag gatccgattg ggctgaaggg gggatggaat ttttatcagt atccgttgaa
       61 tccagttacg aatacagatc ctctggggtt agaagttttt cctagaccat tccccttgcc
      121 aattccatgg cccaaaagcc ctgcacagca gcaagcagat gataatgctg caaaagcatt
      181 gacaaaatgg tggaacgata cagcatcaca aagaatattt gactctctaa tattgaataa
      241 tccgggacta gcattagata taacaatgat agcttctcgt ggaaatgttg cagacacagg
      301 gataactgat cgtgtcaatg acataataaa tgacagattc tggagtgatg ggaaaaaacc
      361 cgacagatgt gacgtacttc aggaactaat tgattgtggt gatattagtg ctaaagatgc
      421 aaaaagcaca cagaaagcct ggaattgtcg tcactccaga cagtcaaacg ataaaaaaag
      481 atagcccttg tggaggttcc tgcaatgtca aatacatacc agaaaagaaa ggcaagtaaa
      541 gagtatggtt tatataatca atgtaagaaa ctaaatgatg atgaattatt tcgcttactt
      601 gatgatcaca attccttgaa aaggatttca tctgccagag tattacagtt aagaggtggg
      661 caagacgctg ttagattggc aattgagttc tgctctgata aaaattatat ccgtagagat
      721 atcggagcat ttatactcgg gcaaataaaa atttgcaaaa aatgcgaaga taatgttttt
      781 aatattttga acaatatggc attgaatgat aagagcgctt gcgttcgagc tacggcaatc
      841 gagtcaacgg ctcagcgatg caagaaaaac ccaatttatt cacctaaaat agtagaacaa
      901 tctcaaatta ctgcttttga taaatcgact aatgtcagac gtgctacagc atttgctatt
      961 tctgttatca atgataaagc aacaattcca ctattgatta atctgttaaa agatccaaat
     1021 ggagatgtca gaaactgggc cgcatttgca ataaatatca ataaatatga taatagtgat
     1081 attagggatt gttttgtgga gatgcttcag gataaaaatg aggaagtccg tattgaagca
     1141 ataatcggac tttcctacag aaaagataaa agggttttat ctgttttatg cgatgagtta
     1201 aaaaaaaata ctgtttatga tgatatcatt gaagctgcgg gtgaattagg tgataaaacg
     1261 ctacttcctg ttttagatac tatgttgtac aagtttgatg acaatgaaat tataacttcc
     1321 gctattgata agctgaagcg ttcatagcgt gagttgccta tgcacagtgg gggattcccg
     1381 ccggcacggt gcagatgctc gaccggctgg aaagtgaaat cctggctgac cgggtgagtg
     1441 aggaaagccg ccgctggctg gcatcgtgcg gcctgaccgt ggagcagatg aaaaaccaga
     1501 tggacccggt gtacacgccg gcgcgaaaaa tccacctgta ccactgcgac catcgcggcc
     1561 tgccgctggc gctcatcagc acggaagggg caacagcgtg gtgcgcagaa tatgatgaat
     1621 ggggcaacct gctgagtgat gagaacccgc atcatctgca gcagctcatt cgcctgccgg
     1681 gtcagcagta tgatgaggag tccggcctgt attacaaccg ccaccgctat tatgacccgc
     1741 tgctggggcg gtatatcact caggatccga ttggactgaa ggggggatgg aatttttatc
     1801 agtatccgtt gaatccggtc ataaatgtag atccgcaagg tttggttgat ataaatttat
     1861 accccgaaag tgatcttatc cattctgtag ctgatgagat taatatccca ggcgttttca
     1921 caatcggggg gcatggtacc cccacatcta ttgaatccgc aacgcgcagt atcatgacag
     1981 ctaaagatct agcatatcta attaaatttg atgggaatta taaagatggg atgacagttt
     2041 ggttattttc ttgtaataca ggtaaaggac aaaattcatt tgctagccaa ttagctaaag
     2101 agttacatac aaatgtaata ggacctgaca cgctatggac gtggtggggg cgaggaacta
     2161 atggtaagtt aaaaatggat acagtgctaa cagcaccaac gaaccttaat tcaaataagg
     2221 atctaatggc tataacaaca aaagaccttg gtaattggat aacatatggg ccatctgggc
     2281 accccatttc taatatgcaa ggtacgccag aaaaacccag tgatataaga taggttgtag
     2341 atgtatgaaa gcatgcttgt tactattttt ttatttctct tttatttgtc aattgcatgg
     2401 tgctgatgtg aaaataaaac aaaacgaaag tatgatgggg tctacagcaa tgacctatga
     2461 tttaagtgaa gaaaagttga tgaaactgaa gtataaatca caacatggtg attcagaggc
     2521 atcatttcga ctatatcaat attactgctt tactaaaaat aacatttaca aacaattgcg
     2581 attcttggaa agatcagcat ctcaggggaa tgttacagcg cagtttaatt atggggtctt
     2641 tttatcagat acaaatccaa cattatcaga atattataat ttgaatagag ctatttattg
     2701 gatggaattc gctgtaaata acggtaatat tgatgcaaag agcaaacttc aagagctcaa
     2761 aaagctaaag cgaatggata gaaggaagaa taaggagaat ccgtaaaagc aatagttcat
     2821 cagactgccg cagcagtagt atgatgatga atcagggctg tactataact attatcggta
     2881 acattaaccg cagcaggggc ggtataacac tcaggctccg attgggctgg aaggtaggtg
     2941 gaatttttat cagtatccgt tgaatccgat ttctggaatc gatccccttg ggattagcca
     3001 cctgtttata cagcataact ttaggtatgc tttcgtgtgt ttcagatata ccatgtgatg
     3061 ataattttta tgatgtgctt agtattccag tcgcttctgg taataatatg caatgtaaaa
     3121 ataatccccg ttgtacacat ttataaatag atggccaata cctcaaggcc tatggagttg
     3181 gaatgttaat gacccgggag caagcaatag aaaacctgac ggcatacgat tagtaccgtc
     3241 agttaataca ggaacttata atcgcaatgg attttcaata catagttgtt taaacgcttt
     3301 tggtccgtct ttaggacctc gattctgttc cgagggttgt ataactggtt tatctaatga
     3361 catgcaaaaa ttaaatgagt taatattttc agagccagat agcacattaa cagttacgga
     3421 ctaaaaaata tggcaaggtt attaacaatt gtattttttt ctctatttct gcgagtgcag
     3481 ttactgcaag acaatttcag agagagttag atttggcaga caaagcaata ttatgggcac
     3541 taatatcagc cagtactaaa gagggacgaa aagcgtgttc actaagctat tttgcctgta
     3601 aggccgcaga ggctgaactc ggactggcat atatggctgc gaatgataac aaggaatttc
     3661 tcacatcctt atctaatata atgaggtaca aaatagatgc tggactttcc gaatcctata
     3721 catgctattt attaagtaag ggaaagatca taagaccata tctgaaaaat ctaaatccac
     3781 tccaacttgc cgctgattgc attgaaacag taaataaaat aaaagataag aataaaaaaa
     3841 atcattgata taaattcagt taatatttgt agtgatgata aaaatataaa attgagagtt
     3901 aatagtacta ttatggccat tgatgattct ataaagtgca tcgatgaatg ataacttaat
     3961 tttatttaaa aatatattaa taactcactc tccaggagtt tttttaactt agttttataa
     4021 tgaatacgat aattaaaagt gaagaagaaa atagttgtat acatatattc catgacccta
     4081 cattgtgatc tatagattaa atatttttta aatgtgactg tcatccttca gataataaag
     4141 ccatcatcgc aatagatgga aaagcactcc tgctcttttt tgattagagc cgtcgcagga
     4201 ggaacaactc atatcatcat tgcgatctcg acgatgtata gtctcatcct gcggcagaac
     4261 aagacggata aaaaatccaa tgagagcaca ctcatccaga acttattaac ataatgaata
     4321 ttaaagaaaa atcatcgcag ctaatgaagt aatatgcaaa aataattagt ccttacaagg
     4381 agcaaagttc cataatctcc cccctccccc tcaatgatcc aaataaagat aatgcatcca
     4441 gctggtcatt cttagcagca ctttccgcat caccgaaaca tggctgaaat ggtcggagta
     4501 aaccgccacc tgggcgtaga tgccgtcggg taaggcatcg atatcatcgt tagggtccag
     4561 ttcaatggtt cccagcacac cgtccgtgcc gggcacgacc gttaatgatt gcaatacccc
     4621 ctgcgcctga taagaaccgc ctggcacgac aggtaaaata ctagtcagtt tgccgtgaaa
     4681 cacctgccca ggtagcgcgt taaacaccac ttccgcatca tcgccgggtt tcagacgtaa
     4741 cagcgagttt tgccgaaatt gggcgacaat ttgccgtttt tgctcgggga tgaagaccat
     4801 caccggacgc agcggcaagg cagctgcgta tgtacctggg cggatcagta cctgagtaac
     4861 gtagccattg ctcggcgcgc gaatgacagt ctgctcaagg ttatattttg cttcagtaag
     4921 ttgcgctctt aagctcacaa tctgcgattg ctcgccgtta accatactgt cgagctggct
     4981 ctggatctgc gcctgctccg ccaccgagcc tttcaccagc gcatcctgcg cgaggaaatt
     5041 ttgccgcgca tcgtcgatgt cacgttccga gaacggattc accgccgcct ggctgccttt
     5101 caagtaacgt tgataatttt taaacagacg gtcgcgctcc gctgaaacct gggtggtgtt
     5161 ggcctgcgct tcagtgagct gcgcacgcag cgtctttata ttatgcgtcg ccgtcatcag
     5221 gtcagcctga agtctgtcaa ctcgcgcctg gtaacgaacc gggtcgagct taaaaagcac
     5281 ctcgcccttt tgaataagct gattattctt gtcagtgact tcagtaacaa ttcccgtcac
     5341 ctgtggcgtg atagggatcg ctatcactgc cttttgcgcg gtaaaagtgt aagggtggtt
     5401 gtagttcatc aacaaaatca aaccactcac cagaaacacg cctcccagcg ccgccgtcgc
     5461 cagcgtccac tgatttaccg gaatgcggaa gattttaaag accgcccacg ccagcgccac
     5521 gtaagttaaa acaatcaata gatccataat tagatctccg ggaacgtgga atagtcagtc
     5581 tttttctcgg cggcgagttg atgctccagc cgggaaattc ggtcagaaag tgcggcgatt
     5641 tccgggtcag tcgctttctc ctgcgacgca acatgtgact gcatacccca gccacgctcc
     5701 ggttgataga gcgtcgccca gatccacaga aacggccaga taacatgcag agtaaacagg
     5761 ctcacccagc ccgccgtatg aatagcgtcg gcatggggat ggttgcgctt tttggcaatc
     5821 agataaggga tgtcatgtat cgcgatgatt ccataaaaaa tcaccagaaa gacgaagatc
     5881 agcactccca acgcgaaata gtttagaaac atatctgcct cggattcacg tttatcagtg
     5941 ttgtttttgg gctggcagcc agaagggagt caggctgata ttttgacaat aatccgggtt
     6001 cgcgattctc gccataacac caaagaataa tttttagagg tgatgagttg cttagttaca
     6061 taacgattgt atgacgaagg cataacatgc tgtagatcac atcaggtgaa cgccgtaaga
     6121 aaatatcttg tgattcagat cacaaagatt caacaaacca tcaaaacaaa aatgtgacac
     6181 tactcacatt taaatgccat ttttagcgaa aatcgccgcc ttgttgcttt tttacacaag
     6241 cgttttgtga tgaacgtcac gtcaattacc tctctacccc ctatatttat gtgattgata
     6301 tcacacaaaa ggccgtcgac tggacagtta accgattcag tgccagattt cgcagtatct
     6361 acaaggtccg gctacctctg ccgccacatt aacaaaaaac ctcgggcttc cagcctgcgc
     6421 gacagcaaac ataagaaggg gtgtttttat gtcatccgat attaagatca aagtgcaaag
     6481 ctttggtcgt ttcctcagca acatggtgat gccaaatatc ggcgcgttta tcgcgtgggg
     6541 tatcatcacc gcgttattta ttccaacagg gtggttaccg aacgagacgc tggcgaagct
     6601 ggtcgggccg atgatcactt atctcctgcc gctgctgatc ggttataccg gtggtaagct
     6661 ggtaggcggc gaacgtggcg gcgtagtcgg tgccatcacc accatgggcg ttatcgtcgg
     6721 cgcagacatg ccgatgttcc tcggttctat gattgcaggt ccgctgggcg gctggtgcat
     6781 taagcacttc gaccgctggg tagacggtaa gatcaaatcc ggttttgaga tgctggtgaa
     6841 taacttctcc gcaggcatca ttgggatgat cctcgctatt ctggcattcc tcggcattgg
     6901 cccgattgtt gaagccctgt ccaaaatgct ggctgcgggc gttaacttca tggttgtcca
     6961 tgacatgctg ccgctggcgt ctatctttgt tgaaccggcg aaaatcctgt tcctcaacaa
     7021 cgccattaac cacggtatct tctcgccgct gggtattcag cagtcccatg aactgggtaa
     7081 atcaatcttc ttcctgattg aagctaaccc aggtccaggt atgggcgtgc tgctggcgta
     7141 catgttcttt ggtcgtggta gcgctaaaca gtctgcgggc ggtgcggcaa tcatccactt
     7201 cctggggggt atccacgaaa tctacttccc gtatgtgctg atgaatccgc gtctgatcct
     7261 cgcagtcatc ctcggcggta tgactggcgt gttcacgctg actatcctgg gcggtggtct
     7321 ggtttctccg gcatctccgg gttctatcct tgctgtactg gcgatgacac caaaaggtgc
     7381 ttacttcgct aacatcgcgg gtgtgtgtgc ggcgatggct gtctccttcg ttgtctctgc
     7441 tattttgctg aaaaccagca aagtgaaaga agaagatgat attgaagcag caactcgtcg
     7501 tatgcaggac atgaaagctg agtctaaagg cgcatctccg ctgtctgctg gcgatgtgac
     7561 taacgacctg agccacgtac gtaaaatcat cgttgcctgt gacgccggta tgggttccag
     7621 tgcgatgggc gcaggcgttc tgcgtaagaa aattcaggat gcaggtctgt cgcagatttc
     7681 tgttactaac agcgcgatca acaacctgcc gccagatgtg gacctcgtca tcactcaccg
     7741 tgacctgacc gaacgcgcta tgcgccaggt tccgcaggca cagcatattt cgctgaccaa
     7801 cttcctcgac agcggcctgt acaccagcct gaccgaacgt ctggttgctg cccaacgcca
     7861 cacggcaaac gaagagaaag taaaagacag cctgaaagac agctttgacg attccagtgc
     7921 taacctgttc aagctaggcg cggagaacat cttcctcggt cgcaaagcgg caaccaaaga
     7981 agaagcgatt cgttttgctg gcgagcagct ggtgaaaggc ggttacgttg agccggaata
     8041 cgttcaggcg atgctggatc gtgaaaaact gaccccgact tatctgggtg agtctatcgc
     8101 ggtgccacac ggtacggttg aagcgaaaga tcgcgtactg aaaacgggcg tcgtgttctg
     8161 ccagtacccg gaaggcgtgc gcttcggtga agaagaagat gacattgccc gtctggtgat
     8221 tggtattgct gcccgtaaca acgagcacat tcaggttatc accagcctga ccaatgcact
     8281 ggatgatgag tccgtcatcg agcgtctggc acacaccacc agcgtggatg aagtgctgga
     8341 actgctggca ggtcgtaagt aatccaatcc caccctctcc acatggagaa ggtggggtta
     8401 attgcctgat gcgctacgct tatcaggcct acaggatgca tcacaatttg ttgaatttgc
     8461 acgttcttgt aggccggata aggcgcttac gccgcatccg gcgctgcccc tctcctcacg
     8521 gagagggttt gggtgaggga aaagcctcac cccagccctc tcgggtaaaa acattgatga
     8581 aggttaatac tatgaaagca ttacattttg gcgcaggtaa tatcggtcgt ggctttatcg
     8641 gtaaactgct ggcagacgcg ggtatccaac tgacgtttgc cgatgtcaat caggtggtac
     8701 ttgatgccct gaatgcccgt catagctatc aggtacatgt ggttggtgaa accgagcagg
     8761 tagataccgt ttccggcgtc aatgctgtca gcagcattgg tgatgatgtc gttgatctga
     8821 ttgctcaggt tgatttagtc actaccgccg ttggcccggt tgtgctggaa cgtattgctc
     8881 cggcaatcgc caaagggctg gtgaaacgta aagaacaagg taatgaatcc ccgctgaaca
     8941 tcatcgcctg tgaaaacatg gtacgcggta ccacgcagct gaaaggccat gtgatgaacg
     9001 ccctgccgga agacgccaaa gcgtgggtag aagaacacgt tggctttgtc gattccgccg
     9061 ttgaccgcat cgtaccgcct tcggcttcgg caactaacga tccgctggaa gtgacggtag
     9121 aaaccttcag cgaatggatt gtcgataaaa cgcagttcaa aggcgcactg ccgaacatcc
     9181 caggcatgga gttaaccgac aacctgatgg catttgtcga acgtaaactc ttcaccctga
     9241 acacgggtca tgctataacc gcgtacctcg gaaaactggc cggtcatcag accattcgtg
     9301 acgcgattct cgacgagaaa atccgcgcgg tggtaaaagg tgcgatggaa gaaagtggtg
     9361 cagtattgat caagcgctac ggctttgacg ctgacaagca tgcggcgtac atccagaaaa
     9421 ttctcggccg ttttgagaac ccgtatctga aagatgatgt agagcgcgta ggccgtcagc
     9481 cactgcgtaa actgagtgct ggcgaccgtc tgatcaagcc actgctcggt acgctggaat
     9541 atggtctgcc acataaaaac ctgattgaag gtattgccgc tgcaatgcac ttccgcagtg
     9601 aagatgatcc gcaggctcag gaactggcag cactgatcgc tgacaaaggt ccgcaggcgg
     9661 cgctggcaca gatttccggt cttgatgcca acagcgaggt tgtatccgag gcggtaaccg
     9721 cttataaagc aatgcaataa tggtggacca ggcgcaggac accctgcgcc cgaataacag
     9781 attgtcagat atgcaggcaa caatggaaca aacccaggcc tttgaaaacc gtgtgcttga
     9841 gcgtctgaat gctggcaaaa ccgtgcgaag ctttctgatc accgccgtcg agctcctgac
     9901 cgaggcggta aatcttctgg tgcttcaggt attccgcaaa gacgattacg cggtgaagta
     9961 tgctgtagaa ccgttactcg acggcgatgg tccgctgggc gatctttctg tgcgtttaaa
    10021 actcatttac gggttgggcg tcattaaccg ccaggaatac gaagatgcgg aactgctgat
    10081 ggcattgcgt gaagagctaa atcacgacgg caacgagtac gcctttaccg acgacgaaat
    10141 ccttggaccc tttggtgaac tgcactgcgt ggcggcgtta ccaccgccgc cacagtttga
    10201 accagcagac tccagtttgt atgcaatgca aattcagcgc tatcaacagg ctgtgcgatc
    10261 aacaatggtc ctttcactga ctgagctgat ttccaaaatc agcttaaaaa aagcctttca
    10321 aaagtaagca acgtctgctt actgcccctc tacctgcttc ggccgataaa gccgacgata
    10381 atactccaga cgttgtagat ataacggcac gctttcatcg ggtattccgg acggaatcgc
    10441 gttacgggga ggaagttttt tcagatactc ccggaacgcc tggcttgatg ccatgaaatc
    10501 tacggcttta tcgataagaa gcggaacgtt ttcacctaat ttgcccatga tgatatctcc
    10561 gtattacccc gcgccgggaa tgcgcggccg ccaattttag tttaggttcc cggtaaagat
    10621 gacattaagg aaaacgtgct gaatcctcaa taatcatccg ctgctgttta ttatcttttt
    10681 tctatagatt tcttaattaa tcaacgaatt gcgtagtttt tgagcatgtt aatgattacg
    10741 ttacagaact attacaatgt cattagttgt gaacaaagca cctggtcgcg catactaggg
    10801 gctataaatt tatctttatc agaagccatc acatgaaaga agtcgaaaaa aacgaaatca
    10861 aacgtctcag cgatcgcctg gacgccatcc gccaccagca ggccgatctt tcgctggttg
    10921 aagccgcaga caaatatgcc gagctggaaa aagagaaagc cacgctggaa gcagaaattg
    10981 ctcgcctgcg tgaagttcat agccaaaaac tgagtaaaga agcacagaag ctgatgaaga
    11041 tgccattcca gcgcgcaatt accaaaaaag agcaggctga tatgggcaag ctgaagaaaa
    11101 gtgttcgcgg actggtcgtt gtgcacccaa tgaccgcact gggccgcgaa atgggcctgc
    11161 aggagatgac tgggttttca aagaccgcgt tttaagaaca cagtatctac agggtgattc
    11221 tgcacattcc tataggccga gtaaggtgtt cacgccgcat ccggcaagat aaggcgctct
    11281 ggatcaacaa cctaagggca attctctgat gaggattgcc cttttcttta ccagacatct
    11341 ccccccacaa gaattggccc taccaattct tcgcttatct gacctctggt tcacaatttc
    11401 ccaattaaaa ctcacatcaa tgttgccaat acataacatt tagttaacca ttcattgtca
    11461 ttatccctac acaacacaat tggcagtgcc acttttacac aacgtgtgac aaggagatga
    11521 gcaacagact cattacacga tgtgcgtgga ctccaggaga cctgcaatga atctctggca
    11581 acaaaactac gatcccgccg ggaatatctg gctttccagt ctgatagcat cgcttcccat
    11641 cctgtttttc ttctttgcgc tgattaagct caaactgaaa ggatacgtcg ccgcctcgtg
    11701 gacggtggca atcgcccttg ccgtggcttt gctgttctat aaaatgccgg tcgctaacgc
    11761 gctggcctcg gtggtttatg gtttcttcta cgggttgtgg cccatcgcgt ggatcattat
    11821 tgcagcggtg ttcgtctata agatctcggt gaaaaccggg cagtttgaca tcattcgctc
    11881 gtctattctt tcgataaccc ctgaccagcg tctgcaaatg ctgatcgtcg gtttctgttt
    11941 cggcgcgttc cttgaaggag ccgcaggctt tggcgcaccg gtagcaatta ccgccgcatt
    12001 gctggtcggc ctgggtttta aaccgctgta cgccgccggg ctgtgcctga ttgttaacac
    12061 cgcgccagtg gcatttggtg cgatgggcat tccaatcctg gttgccggac aggtaacagg
    12121 tatcgacagc tttgagattg gtcagatggt ggggcggcag ctaccgttta tgaccattat
    12181 cgtgctgttc tggatcatgg cgattatgga cggctggcgc ggtatcaaag agacgtggcc
    12241 tgcggtcgtg gttgcgggcg gctcgtttgc catcgctcag taccttagct ctaacttcat
    12301 tgggccggag ctgccggaca ttatctcttc gctggtatca ctgctctgcc tgacgctgtt
    12361 cctcaaacgc tggcagccag tgcgtgtatt ccgttttggt gatttggggg cgtcacaggt
    12421 tgatatgacg ctggcccaca ccggttacac tgcgggtcag gtgttacgtg cctggacacc
    12481 gttcctgttc ctgacagcta ccgtaacact gtggagtatc ccgccgttta aagccctgtt
    12541 cgcatcgggt ggcgcgctgt atgagtgggt gatcaatatt ccggtgccgt acctcgataa
    12601 actggttgcc cgtatgccgc cagtggtcag cgaggctaca gcctatgccg ccgtgtttaa
    12661 gtttgactgg ttctctgcca ccggcaccgc cattctgttt gctgcactgc tctcgattgt
    12721 ctggctgaag atgaaaccgt ctgacgctat cagcaccttc ggcagcacgc tgaaagaact
    12781 ggctctgccc atctactcca tcggtatggt gctggcattc gcctttattt cgaactattc
    12841 cggactgtca tcaacactgg cgctggcact ggcgcacacc ggtcatgcat tcaccttctt
    12901 ctcgccgttc ctcggctggc tgggggtatt cctgaccggg tcggatacct catctaacgc
    12961 cctgttcgcc gcgctgcaag ccaccgcagc acaacaaatt ggcgtctctg atctgttgct
    13021 ggttgccgcc aataccaccg gtggcgtcac cggtaagatg atctccccgc aatctatcgc
    13081 tatcgcctgt gcggcggtag gcctggtggg caaagagtct gatttgttcc gctttactgt
    13141 caaacacagc ctgatcttca cctgtatagt gggcgtgatc accacgcttc aggcttatgt
    13201 cttaacgtgg atgattcctt aatgattgtt ttacccagac gcctgtcaga cgaggttgcc
    13261 gatcgtgtgc gggcgctgat tgatgaaaaa aacctggaag cgggcatgaa gttgcccgct
    13321 gagcgccaac tggcgatgca actcggcgta tcacgtaatt cactgcgcga ggcgctggca
    13381 aaactggtga gtgaaggcgt gctgctcagt cgacgcggcg gcgggacgtt tattcgctgg
    13441 cgtcatgaca catggtcgga gcaaaacatc gtccagccgc taaaaacact gatggccgat
    13501 gatccggatt acagtttcga tattctggaa gcccgctacg ccattgaagc cagcaccgca
    13561 tggcatgcgg caatgcgcgc cacacctggc gacaaagaaa agattcagct ttgctttgaa
    13621 gcaacgctaa gtgaagaccc ggatatcgcc tcacaagcgg acgttcgttt tcatctggcg
    13681 attgccgaag cctcacataa catcgtgctg ctgcaaacca tgcgcggttt cttcgatgtc
    13741 ctgcaatcct cagtgaagca tagccgtcag cggatgtatc tggtgccacc ggttttttca
    13801 caactgaccg aacaacatca ggctgtcatt gacgccattt ttgccggtga tgctgacggg
    13861 gcgcgtaaag caatgatggc gcaccttagt tttgttcaca ccaccatgaa acgattcgat
    13921 gaagatcagg ctcgccacgc acggattacc cgcctgcccg gtgagcataa tgagcattcg
    13981 agggagaaaa acgcatgatt atttccgcag ccagcgatta tcgcgccgca gcgcaacgca
    14041 ttctgccgcc gttcctgttc cactatatgg atggtggtgc atattctgaa tacacgctgc
    14101 gccgcaacgt ggaagatttg tcagaagtgg cgctgcgcca gcgtattctg aaaaacatgt
    14161 ccgacttaag cctggaaacg acgctgttta atgagaaatt gtcgatgccg gtggcactgg
    14221 ctccggtggg tttgtgtggc atgtatgcgc gtcgtggcga agttcaggca gccaaagcgg
    14281 cggacgcgca tggtattccg tttactctct cgacggtttc cgtttgcccg attgaagaag
    14341 tcgcgccagc catcaagcgc ccaatgtggt tccagcttta tgtactgcgc gatcgcggct
    14401 ttatgcgtaa cgcgctggag cgagcaaaag cagcgggttg ttcgacgctg gttttcaccg
    14461 tggatatgcc gacaccgggc gcacgctacc gtgatgcgca ttcaggtatg agcggcccga
    14521 acgcggcaat gcgccgctac ttgcaagcgg tgacacatcc gcaatgggcg tgggatgtgg
    14581 gcctgaacgg tcgtccacat gatttaggta atatctcagc ttatctcggc aaaccgaccg
    14641 gactggaaga ttacatcggc tggctgggga ataacttcga tccgtccatc tcatggaaag
    14701 accttgaatg gatccgcgat ttctgggatg gcccgatggt gatcaaaggg atcctcgatc
    14761 cggaagatgc gcgcgatgca gtacgttttg gtgctgatgg aattgtggtt tctaaccacg
    14821 gtggccgcca gctggacggt gtactctctt ccgcccgtgc actgcctgct attgcagatg
    14881 cggtgaaagg tgatatagcc attctggcgg atagcggaat tcgtaacggg cttgatgtcg
    14941 tgcgtatgat tgcgctcggt gccgacaccg tactgctggg tcgtgctttc ttgtatgcgc
    15001 tggcaacagc gggccaggcg ggtgtagcta acctgctaaa tctgatcgaa aaagagatga
    15061 aagtggcgat gacgctgact ggcgcgaaat cgatcagcga aattacgcaa gattcgctgg
    15121 tgcaggggct gggtaaagag ttgcctgcgg cactggctcc catggcgaaa gggaatgcgg
    15181 catagtcgtt tgcgccccct caccctaacc ctctccctca gggagagggg accgttcggc
    15241 gctgtatgta ctccctcact ctgaaacgac accgcactct ttttttctcc ctcgcccctc
    15301 cggggagagg gccggggtga ggggaaaagg ccgcactgct caccaatttt ctgctatcct
    15361 gcccccgcac taagggggca gtatgctaaa catcgtactt tacgaaccag aaattccgcc
    15421 aaatactggc aacatcatcc gtctttgcgc taataccggc tttcgtctgc atatcatcga
    15481 accgatggga tttgcctggg acgataagcg cctgcgccgc gcggggctgg actatcacga
    15541 gtttaccgcc gttacgcgtc atcatgacta tcgcgcgttc ctcgaagcag aaaatcccca
    15601 gcgcctgttc gccctcacca cgaaaggtac acctgctcac agcgccgtaa gctatcagga
    15661 tggcgattat ctgatgttcg gcccggaaac acgcggcctg ccagcgagca ttcttgatgc
    15721 cctgcccgct gaacaaaaaa ttcgcattcc gatggtgccg gacagccgca gcatgaatct
    15781 gtccaatgcg gtgtcggtag tggtgtatga agcctggcgg cagttggggt atccgggagc
    15841 ggtattgaga gattagttac tgtaggccgg atagatgatt acatcgcatc cggcacgatc
    15901 acaggacatt agatcccatc cccatactca aatgtatggt taataccgtt gaaatgctgg
    15961 tccatatcca ttgatggctt atcgctgtct ggtttaccga caatacgagc cggaacgcca
    16021 gcggcggtgg tatgcggcgg caccggttgc agcaccacgg aacctgcgcc aatcttcgcg
    16081 ccgcgaccaa cttcaatatt gccgaggatt ttcgcgcccg cgccaatcat cacaccttca
    16141 cgaattttcg ggtgacggtc accaccagat ttacccgtac cgccaagcgt cacagattgc
    16201 agaatcgata cgtcgttttc aattaccgcc gtttcaccca caacgatgcc cgtggcgtgg
    16261 tcgagcataa tgccacggcc aatttttgct gccgggtgaa tatcgacctg gaacgtcaca
    16321 gaaacctggt tttgcagaaa gattgccaat gcgcgacgcc cctgattcca caaccagtga
    16381 ccgatgcgat aggcctgcaa ggcatgaaaa cccttcaggt ataacaacgg ggttgagtat
    16441 ttatcgactg ccgggtcgcg ggtacgcacc gcctgaatat cacaggccgc agaggcgatc
    16501 atttccgggt cagcggcgta ggcttcttcc accacttcac ggatagcaat agcaggcata
    16561 attggcgatg acagcttgtt cgccagcatg tagctcagtg cacttccaag gttttcgtgc
    16621 ttgagtagcg tcgcgtggta aaaactggcc agcattggct cacagtccgc cagcgttctg
    16681 gcttcggctt taatattgtt ccagacaatt tccagttctt cacacgacat tgcttactcc
    16741 acacgatgag ataatgaccg gcccgttctg cgcgggccgg gtcatagcgg taacaaaggt
    16801 tccctggggt tagtggctgc tgcgctcgtc cttgcgtgca cgacctaata acgtcaatgc
    16861 tgcctcgcgc gcgttttttc cgcaatataa tacttgataa atttcctcgg ttattggcat
    16921 ttctacgccg aagcgatgcg ccagttcgcg gacttctttc gtattgcggt agccttccac
    16981 cacctgacca atcttctcct gcgcgctttg tacatccatg ccctgaccga gcatcatgcc
    17041 aaaacggcgg ttacgcgact ggttgtcggt acaggtaagc accagatcgc caagccccgc
    17101 catgcccata aaggtggcag ggtcggcacc cagcgccgcg ccaagacgcg acatttcagc
    17161 cagcccacgg gtgatcagcg ccgtacgcgc attcgcacca aaaccgatac cgtcggacat
    17221 ccccgcacca atggcaatga cgtttttcac cgcgccgcca agctgcacgc caatgaaatc
    17281 cgggttactg taaacgcgga aacttttgcc gcagtgcagc agctgctgaa gatcatcagc
    17341 aaaggtctga tcggtcgagg ccagcgaaat agctgtcggt aaacctgccg ccagttcttt
    17401 cgcaaacgtt gggccagaga taaccgccag cggaatttga tcgcctaacg cctcgcgggc
    17461 cacgtcctgt aacagacgcc cggtttccgc ttccagccct ttggtcgccc acaccagacg
    17521 cgcatcagga cgcatcagcg gtttaatctg gcgcagcact tcaccaaaga catggctggg
    17581 tacgacgacg agaatattac ggctggctgc cagcgcagtg gcgagatcgc tttcaagatg
    17641 gagcgtatcg ggaaaaggca catcggggag aaacgcggcg ttacagcggt cgcgttcaag
    17701 cgttgcgata tgttcagggt catggcccca gaggacaacc tcgtggccat ttcttgccag
    17761 ggtaatggca agagcggtgc cgtacgagcc ggcaccgatc acagtcattg aagcattacg
    17821 ttggttcatc aggcatcctg atgttcttca gtaccttcgc cagcctgctg ctgcaaatag
    17881 ttcatgaaca gcgcatcgaa gttaaccggc gcaaggttca gttgcgggaa tgtaccgcgg
    17941 gataccatgc tggtgatgca ctcacgagca tacgggaaca gaatgttcgg gcagtatgcg
    18001 cccaggcaat gtgccatctg ggtgccttcg atacccgcga tggagaaaat accgccctgc
    18061 tgaacttcac acaggaacgc ggtttcttcg cccagggagg ccgttacggt aacacgcagt
    18121 accacttcgt aaacgtcatc tgccagttga gtagatgccg tatccagatc aagtttaact
    18181 tctggctgcc aatctttctg gaaaacgtgc ggcgcgttcg gcgcttcgaa agaaatatcc
    18241 ttggtataaa tacgttggat ctggaaagtc atttcggtgt tgttttgttc tgacatgtgt
    18301 agaaaaccct taagtgttgt ccttaaatac tgcgcaatgt aatgccaacg ttcacacgtt
    18361 atttcagcag gggatccagt ccaccacgtg catccaatgc atacaagtca tcacagccgc
    18421 caatgtgctg tgcgtcaata aaaatctggg gaaccgtggt gcgaccgctg cgtttgatca
    18481 tctcttcacg cttggcggca ttgccatcga tcggcaactc ctgaaaactc acgcccttgc
    18541 tgctcagcag tgcttttgca cgatggcaat acgggcaggt ttctttggta tagatttcaa
    18601 cattggccat aatttagctc ctgttttttt accctgaaat ttcatgttgc agggcggctg
    18661 caaaatggag tgtccccaga agcttataac aataagtcgc tgggggccta attgcagcta
    18721 acggcctgca tcatgaaaga cgacaggtaa attatttgcc gcgcaccaaa ggcaagtttt
    18781 cgccagccca gccagcgacg ccttctttca gcacgaatac ttgcgcaaaa ccagctttcg
    18841 tcagtgcgtt tgcaggctcc tggcactgca tgccagaacc gtctaccacg ataaccggtt
    18901 tgtctttgtg cttctcaagc tcaccaacat tgttggcttt gatttcgctc ggcaacagat
    18961 tgatagaacc tgcgatatgg cctttacgga agtcatcacg ctgacgtaaa tccacaacca
    19021 cagcgtcttc tttgttgatc agacgcgtag cttcaccacg agtaatcacc ttcactttcg
    19081 aggtcaggct cttaaacgta gtcacaagaa ccgccaccag taacgcgatc caggcgatac
    19141 tcagtatggg atgacggcca acaaattgca taatttcttg catggggggt aacaactccc
    19201 gacgtagtga ttaaaaaaac caggaaagga gtatacctgc gcggtgcggc aaatacagcc
    19261 agcgcgttag ctggaatgca attttgcggg gcacgacgaa aaaaaagcgc aaatctggca
    19321 tcggcttgcc gcgagcggtc gtatattttg atcttcagag tctattttat cgattcagct
    19381 gtagtaaaat tacgcaaatt ttgactcttg agtatgaggt tgtcgcaatg tcggtttcta
    19441 aaaaacctat ggtactggtg attctggatg gctatggcta tcgtgaagaa cagcaggata
    19501 acgccatttt tagtgctaaa accccggtaa tggatgcact gtgggccaat cgtccgcata
    19561 ccctgatcga cgcttccggt ctggaagtcg gtctgcctga ccgtcagatg ggtaactccg
    19621 aagtaggcca cgttaacctg ggtgccggcc gcatcgtgta tcaggacctg actcgtctgg
    19681 acgttgaaat caaagatcgc gctttctttg ctaatccagt gctgactggc gcggtagata
    19741 aagcgaaaaa cgcaggtaaa gcagtacaca ttatgggtct gctctccgca ggcggcgtac
    19801 acagccacga agatcacatc atggcgatgg tagaactggc agctgaacgc ggcgcagaaa
    19861 aaatctacct gcacgcattc cttgacggtc gcgacacccc gccgcgcagt gctgaatcct
    19921 cgctgaaaaa atttgaagag aaatttgctg cgctgggtaa aggccgcgta gcgtccatca
    19981 ttggtcgtta ctacgcgatg gaccgcgata accgttggga tcgcgttgaa aaagcctatg
    20041 acctgctgac tctggcgcag ggtgagttcc aggccgatac tgccgttgct ggtttgcagg
    20101 cagcttatgc tcgcgacgaa aacgacgagt tcgtgaaagc gaccgttatt cgtgcagaag
    20161 gtcagccaga tgcggcaatg gaagacggcg atgcgctgat tttcatgaac ttccgtgctg
    20221 accgcgcgcg cgaaatcact cgtgcattcg taaacgcaga tttcgacggc ttcgcgcgta
    20281 agaaagtggt taacgtcgat ttcgtgatgc tgaccgaata cgccgctgac atcaaaactg
    20341 cggttgctta cccacccgct tccctggtta acaccttcgg cgagtggatg gcgaaaaacg
    20401 acaaaactca gttgcgtatt tccgaaaccg aaaaatatgc ccacgttact ttcttcttca
    20461 acggtggcgt agaagagtcg ttcaaaggcg aagatcgcat tctgatcaac tcaccgaaag
    20521 tggctaccta cgatctgcaa ccggaaatga gctccgcaga gctgaccgaa aaactggttg
    20581 cggccatcaa gagcggcaaa tacgacacca ttatctgtaa ctatccgaac ggtgacatgg
    20641 taggtcacac cggggtgatg gaagcggcgg ttaaagcggt tgaagcactg gatcactgcg
    20701 tggaagaagt cgcgaaagcg gttgagtccg tgggtggaca actgctgatc accgctgacc
    20761 acggtaacgc tgaacagatg cgcgatccgg caacgggtca ggcacacacg gcacacacca
    20821 acctgccagt tccgctgatt tacgttggtg ataagaacgt gaaagcggtt gcaggcggca
    20881 aactttctga catcgcgccg accatgttgt cgctgatggg tatggaaatc ccgcaagaga
    20941 tgactggtaa gccgctgttc atcgtggaat aatccctccc catgagggga aaggcgatta
    21001 ataccatgac acgggccgtg aaaccgcgca ggtttgcaat caggcccatc atctacgcca
    21061 gcgttcttag cgctggcgta ttgttgtgcg ccttttccgc ccatgcggat gagcgtgacc
    21121 aactcaaatc tattcaggcc gatatcgccg cgaaagagcg cgcggtacgc caaaagcaac
    21181 aacaacgcgc aagcctgctc gcacaattga aaaagcagga agaagcgatc tctgaagcca
    21241 cccgtaagct gcgcgaaacg caaaacacgc tcaatcaact caataaacag attgatgaga
    21301 tgaacgcgtc gattgccaaa ctggagcagc aaaaagccgc ccaggagcgc agcctcgccg
    21361 cacaactgga tgccgcattc cgtcagggcg agcataccgg tattcagctg attctcagcg
    21421 gtgaagaaag ccagcgtgga cagcgtttac aggcttattt cggctatctc aaccaggcgc
    21481 gacaagaaac cattgcccag ttgaagcaaa cgcgtgaaga agtcgccatg cagcgtgctg
    21541 aactggaaga gaaacaaagc gagcaacaaa cgctgttata tgaacagcgc gcccaacagg
    21601 cgaaactgac tcaggctctg aatgagcgta aaaagacgct ggcggggctg gaatcttcca
    21661 tccagcaagg tcagcagcag ctaagtgaac tgcgtgccaa cgaatcccgt ctgcgtaaca
    21721 gcattgcccg tgcggaagcc gcggcgaaag cgcgtgcaga acgagaagca cgtgaggccc
    21781 aggcggttcg cgaccgccag aaagaagcga cgcgcaaagg caccacctac aaaccgaccg
    21841 aaagcgaaaa atcgctgatg tcccgaactg gtggcctggg tgcgccgcgt ggtcaggcat
    21901 tctggccggt tcgcgggccg acgctgcatc gctatggcga gcagctacag ggtgaattac
    21961 gctggaaagg gatggtgatt ggtgcctctg aaggtactga agttaaagcg attgccgacg
    22021 gtcgggtgat tctggctgac tggctgcaag gctacggtct ggtggtggtg gttgagcatg
    22081 gtaaaggcga catgagtctt tacggctata atcagagcgc actggtgagc gttggttcgc
    22141 aggttcgcgc gggccagcca attgcactgg tgggcagcag tggcggtcag ggtcggcctt
    22201 cactctattt cgaaattcgc cgccagggtc aggcggtcaa tccacagccg tggttgggaa
    22261 gataagtttt gtttccattt cgtcgtaacg ttcttgcatt tgccgctctg ttggcgctct
    22321 cctcccccgt acttgctggc aaacttgcca tcgtcattga tgattttggg tatcgcccgc
    22381 acaacgaaaa ccaggtgctg gcgatgccct ccgctatctc cgtcgctgta ttacccgatt
    22441 caccgcacgc cagagagatg gcgaccaaag cgcataacag cgggcacgaa gtgttgattc
    22501 atctcccgat ggcaccactg agtaaacagc cgctggagaa aaatacgctg cgcccggaga
    22561 tgagcagcga cgaaattgag cgcattattc gtagtgcggt caataacgtg ccctatgccg
    22621 tggggatcaa caaccacatg ggtagcaaga tgacctctaa cctgtttggt atgcagaaag
    22681 tgatgcaggc actggagcgt tacaatcttt acttcctcga cagcgtaacc atcggtaata
    22741 cccaggcgat gcgcgccgcg caaggtactg gcgtgaaggt gatcaaacgg aaggtgttcc
    22801 tcgacgattc gcagaacgaa gcggacatcc gtgtgcaatt taatcgcgca attgatctgg
    22861 cgcgtcgcaa cggttcaacc attgccattg ggcatcctca cccttcaacg gtacgcgtgc
    22921 tacaacagat ggtttataac ctgccgccag acattacgct ggtgaaagcc agcagcttgc
    22981 tgaatgaacc gcaggttgat acttctacac cgccgaaaaa cgctgtgcct gatgcaccgc
    23041 gtaatccgtt ccgtggcgtg aagctgtgca aaccgaagaa accgatagaa cctgtttatg
    23101 ctaatcgctt ctttgaagta ttaagcgaaa gcatcagcca gagcacgctg atcgtttact
    23161 tccagcatca gtggcaaggc tggggcaaac agcccgaagc ggcgaagttt aacgctagcg
    23221 caaattaaag gcgctacgcg taatgcgatg gtgcgaccgc gttttgtcgc gccattgcca
    23281 taagcggaaa gaccacagta acgcctggta accgaccttc acgctgcgca cattggtaat
    23341 caggcgctta tacataccgg aagtaaatat ctcggcaatc atccgttggc gggtaagaat
    23401 atccggctct ttgcgcaccg catggcaaac acgcaatgcc tcgtaagtta tttgctgatg
    23461 aaattccgga taaatcataa ttttgtcggc ataatttcga tttaatttct ccagcaggcg
    23521 ggtaatctta atatagtgac gttgataatt aaggttttta ttcccttgtc tatgcaaccg
    23581 actcactgac gtattatgca gataatattt atataatgat tgctcggtat atcgcgcacg
    23641 cagcgcgtta aacatgaatt ctgttgtcca gacaatatcc tgatgatgta atccggcaat
    23701 aaatttaatg ttatttttaa caataacatc acggcgataa acccccatcc agacaacgtg
    23761 agtccaacgg cgcgaagaaa gccccatccg cagccagtcc gggccggtta agacgccggt
    23821 tgagcgaagg cgatcggtgg ggatggattg ccaggtttct cccgtttcac gaaaacacca
    23881 gtcagcgttg cactgcgcca cgtcgaggtc gtcctctaac gccatggtca tcagcgtttc
    23941 gtacatggtg ggatagactt catcgtcagc atcgacaaaa gcgacatatt tgcccgttgc
    24001 cacttcaatc ccacgattac gcgccaccga tgcgccagca ttcgcctgat gcaacaaacg
    24061 aacgtgcgga tagttttctg cgtaatgctt tgctatttca acagaattat ccgttgaacc
    24121 atcgttaata ataatgattt ccagagcagt ccaggtttgc gtaattaaag attccataca
    24181 agtgcggaaa tcatcgcccg cattatataa cggaataata acactaagtt tattggtgct
    24241 gttcatcata aattaccgac gacctctgaa gttatcctga cgttttacag gctttgtatt
    24301 aagaaactat taagcctgtg agatattatt tttacaggtg agagagtcac ttcagggtag
    24361 agagataatg agagcagcta tataagagat cagcacaatt acgaactctt tattacactg
    24421 acaggatttt acatatttaa cagattatcc tcagataaaa gggctggaat accagccctt
    24481 gttcgtgtta atcccagctc agaataactt tcccggactg gcccgaacgc atagcgtcaa
    24541 agcccttctg gaaatcatcg atagagaaac gatgggtaat gatcggcgag agatcgaggc
    24601 cagactgaat cagcgccgcc atcttgtacc aggtttcaaa catctcacga ccgtaaatgc
    24661 ctttaatgaa caagccctta aagatcactt ttgtccagtc tatcgacatg tcagaaggtg
    24721 gaatacccaa catcgcaata cgaccgccgt ggttcatggt gtcgagcatg gtacgaaacg
    24781 ctggcggcgc accggacatt tccagaccga catcaaagcc ttcggtcata cccagttctg
    24841 ccatcacatc attaaggttt tctttagcga cgttgaccgc acgggtgata cccattttgc
    24901 gcgccagttc gagacgatat tcattaacat ccgtgatcac cacattgcgt gcaccaacgt
    24961 gtttcgccac cgccgcagcc ataataccta tcggacctgc accagagacc agcacatcct
    25021 cgccaaccag atcgaacgac agcgcggtat gcacggcatt accgaaggga tcaaaaatgg
    25081 aagccagatc gtcggagata ttgtcgggaa ttttgaaggc gttgaacgcc ggaatcacca
    25141 gatattcggc gaagcagccc gggcggttaa cgccgacgcc gatcgtgttg cggcacagat
    25201 gggtacgacc gccacgacag ttgcgacagt gaccgcaagt gatatggcct tcgccagaaa
    25261 cgcgatcgcc aatcttgaag cctttcactt cctgaccaat acctaccact tcaccgacat
    25321 attcatggcc cacgaccatc ggcaccggga tggttttttg cgaccactca tcccagttat
    25381 agatgtgaac gtcagtcccg cagatggctg ttttacggat tttaatcagc agatcgttat
    25441 gacccagttc cggctcagga acgtcggtca tccagatgcc ttcttccgct ttcagtttgg
    25501 ataacgcttt catttcacat cctcaggcga taacgcccag ttgtttacca atacgcgtga
    25561 atgcttctac tgcgcgcgta atttgctcag aggtatgcgc cgcagacatc tgggtacgaa
    25621 tacgcgcctg acctttcgga acgaccggat agaagaaacc ggtgacgtaa atcccctctt
    25681 tttgcagctc acgagcaaat ttctgcgcca ctaccgcatc gccaagcatg accggaataa
    25741 tggcgtgatc ggctcccgcc agggtaaagc ccgccgccga catttgctca cggaactgac
    25801 gcgcgttcgc ccacaaacgg tcacgtagct cgctgcccgc ttcaaccatc tccagcactt
    25861 tgatggaagc ggcgacaatc gctggtgcca gcgagttgga gaacaggtac ggacgagaac
    25921 gctggcgtag ccactcaacc acttctttgc gcgccgcggt ataaccacca gaagccccgc
    25981 ccagcgcttt accaagcgta ccggtgataa tatcgacccg gcccatcaca tcgcagtatt
    26041 catgggaacc acgaccgttt tcaccgacaa aaccgaccgc gtgggagtcg tctaccatca
    26101 ccagggcatc gtatttatct gccagattgc aaacgccctt cagattggca atcacgccgt
    26161 ccatcgagaa cacaccatcg gtggcaatca gcacatgacg cgcaccggct tcacgcgctt
    26221 ctttcagacg agcttcaagc tcctgcatat cgttgttggc atagcgatag cgtttagctt
    26281 tacacagacg cacaccatca ataatagacg cgtggttcag tgcgtcggag ataatggcgt
    26341 cttccgcacc cagcagtgtt tcaaacaggc caccgttagc atcaaagcag gaagagtaga
    26401 gaatcgcatc ttccatcccc aggaatgcag ccagcttctg ctcaagctct ttgtggctgt
    26461 cctgagtgcc acaaataaaa cgcaccgaag ccatgccgaa accatgagaa tccattcccg
    26521 cttttgctgc cgcaatcagt tccgggtggt tcgccagccc caggtagtta ttggcacaaa
    26581 agttaatgac gtggctacca tccgccacag tgatatccgc ttgttgagcg gatgtgataa
    26641 tgcgctcttc tttaaacaat ccttccgcac gagcggtttc cagatcgttg gctaactgct
    26701 gataaaaatc tccacgcatc gcgattctcc agactgggca aatttcagca catattaccg
    26761 aaagccatag gttgatacga gatgaagcat ttgtacttgt caaaaaataa gcataaatca
    26821 cgctcaggca taccactttc ggtgaatggc tgtagccagc gccgtgtagt gatatgatag
    26881 aagtattcgt gtctgagatt gtctctgact ccacaattcg aaggttacag ttatgatcat
    26941 cgttaccggc ggcgcgggct ttatcggcag caacatcgtt aaagccctga atgacaaagg
    27001 catcaccgat attctggtgg tggacaacct gaaagacggc accaagtttg tgaacctggt
    27061 ggacctgaat atcgcagact atatggataa ggaagacttc ctgatccaga ttatggctgg
    27121 cgaagagttc ggcgatgtcg aagcgatttt ccacgaaggc gcgtgctctt ccaccaccga
    27181 gtgggacggc aagtatatga tggataacaa ctatcaatac tccaaggagc tgctgcacta
    27241 ctgcctggag cgtgaaatcc cgttcctgta cgcttcatcc gcagccactt acggcggtcg
    27301 cacttccgac tttattgaat cccgcgagta cgaaaaaccg ttgaacgtct acggttactc
    27361 gaaattcctg tttgatgaat atgttcgtca aattctgccg gaagcaaact cacagattgt
    27421 tggcttccgt tatttcaacg tttatggacc gcgtgaaggc cataaaggca gcatggcgag
    27481 cgtcgctttc catctcaaca cccagcttaa taacggtgaa tcaccgaagc tgttcgaagg
    27541 tagcgagaac tttaaacgcg acttcgtcta tgttggcgac gtggcagatg taaacctgtg
    27601 gttcctggaa aatggcgttt ccggcatctt caacctcggt actggtcgtg cggaatcctt
    27661 ccaggcggta gccgatgcaa cgcttgctta tcacaagaaa ggccagatcg aatacattcc
    27721 gttcccggat aaactgaaag gccgctatca ggcattcacg caggcagatc tgacgaatct
    27781 gcgcgcggcg ggttatgaca aaccgttcaa aaccgttgcc gaaggcgtaa cggaatacat
    27841 ggcctggctg aatcgcgaca tcaacgtaaa ttcacaaaat cattcgagcg gtatcaaggc
    27901 agcaactaag tgaatctccg ggagcttaca aaagtaagtg accggagtga acgcaggcag
    27961 ccgccgcaga gacagcttga aggatgaagt gaatgaaaat attggtgatc ggcccgtcat
    28021 gggtgggcga catgatgatg tcgcaaagtc tctatcgcac gctccaggcg cgctatcccc
    28081 aggcgataat cgacgtgatg gcaccggcat ggtgccgtcc attattatcg cggatgccgg
    28141 aagttaacga agccattcct atgccgcttg gtcacggagc gctggaaatt ggcgaacgcc
    28201 gcaagctggg tcatagcctg cgcgaaaaac gttacgaccg cgcctacgtt ttacccaact
    28261 ccttcaaatc cgcattagtg cctttcttcg cgggtattcc tcatcgcacc ggctggcgcg
    28321 gcgaaatgcg ctacggttta ctcaacgatg tgcgtgtgct ggataaagaa gcctggccgc
    28381 tgatggtgga acgctatgtg gcgctggcct atgacaaagg tattatgcgt accgcacaag
    28441 atctgccgca gccattgtta tggccgcagt tgcaggtgag cgaaggtgaa aaatcatata
    28501 cctgtaatca attttcgctt tcatcagaac gtccaatgat tggtttttgc ccgggtgcgg
    28561 agtttggtcc ggcaaaacgc tggccacact accactatgc ggaactggca aagcaactga
    28621 ttgatgaagg ttatcaagtg gttctgtttg gctcggcgaa agatcatgaa gcgggcaatg
    28681 agattcttgc cgctttaaat accgagcagc aggcatggtg ccggaacctg gcgggggaaa
    28741 cacagcttga tcaagcggtt atcctgattg cagcctgtaa agccattgtc actaacgatt
    28801 ctggcctgat gcacgttgcg gcggcgctca atcgtccgct ggttgccctg tatggtccga
    28861 gtagcccgga cttcacaccg ccgctatccc ataaagcgcg cgtgatccgc ctgattaccg
    28921 gctatcacaa agtacgcaaa ggcgacgccg cagaaggtta tcaccagagc ttgatcgaca
    28981 ttactcccca gcgcgtgctg gaagaactca actctctatt gttacaagag gaagcctgac
    29041 ggatgcgggt tttgatcgtt aaaacatcgt cgatgggcga tgttctccat acgttgcccg
    29101 cactcactga tgcccagcag gcaatcccag ggattaagtt tgactgggtg gtggaagaag
    29161 ggttcgcaca gattccttcc tggcacgccg ccgttgagcg agttattcct gtggcaatac
    29221 gtcgctggcg taaagcctgg ttctcggccc ccataaaagc tgaacgcaaa gcgtttcgtg
    29281 aagcgctaca agcagagaac tatgacgcag ttatcgatgc tcaggggctg gtaaaaagcg
    29341 cggcgctggt gacgcgtctg gcgcatggcg taaagcatgg aatggactgg caaaccgctc
    29401 gcgaaccttt agccagcctg ttttacaatc gtaaacatca tattgcaaaa cagcagcacg
    29461 ccgtagaacg catccgcgaa ctttttgcca aaagtctggg ctatagcaaa ccgcaaaccc
    29521 agggcgatta tgctatcgca cagcattttc tgacgaacct gcctacagat gctggcgaat
    29581 atgccgtatt tcttcatgcg acgacccgtg atgataaaca ctggccggaa gaacactggc
    29641 gagaattgat tggtttactg gcagattcag ggattcgcat taaacttccg tggggtgcgc
    29701 cgcatgagga aaaacgggcg aaacgactgg cggaaggatt tgcttatgtt gaagtattgc
    29761 cgaagatgag tctggaaggt gttgcccgtg tgctggccgg agcgaaattc gtggtatcgg
    29821 tagacactgg gttaagtcat ttaactgcag cactggatcg accgaatatc acggtttatg
    29881 gaccaaccga tccgggatta attggcggat atgggaagaa tcaggtggtt tgtagggcac
    29941 cagataaaga tcttgctcat ctgactgcag aaacggtatt taataaaatc aattcctgat
    30001 taatacgtta tatattattt aagatggtgg agaagcaatg ttaacagcct cgctggcgct
    30061 acgtaataaa gaaaagtgga aaccgtactg gaataaagcg ttggtattcc tctttattgc
    30121 aacctttttc cttgatggta taacccgtta taaacacatc atatctatac taatgattat
    30181 tacggtaatc tatcaagttt ctcgtgctcc gggaacattt aaagtactct ataaaaataa
    30241 tcttttttat agtgtcctgg cactatcact cattctttta tatgctactt ttatatcacc
    30301 tgatctgaaa atcagtttta aagaattcag taatacggta cttaaaggat ttttggccta
    30361 tagtttactt atacctgcat tattaaaaga tgaagataat gaaagcattg gtaaaattgt
    30421 actatactca ttagttaccg gacttggctt acgttgtctt gttgaactta ttctttatat
    30481 tcaggattat aataaaggaa taatcccatt ttccacctat gaacaccgta gtatttccga
    30541 ttcaatggtg tttctgtttc cagcattatt aaacctttgg cttatcaaga aaacctctta
    30601 taaaatagca ttcgtaattt ttagtgcagt tttcttattt ctgctattag gaacgctgtc
    30661 tcgtggtgca tggctggcag tattcatagt gactctgcta tggttaatct taaatcgtca
    30721 gtggaaatta ttgatgctga cttccatcgt tatttctgtt gccgcagtgg gtgtatttac
    30781 ctataaaggt gatcatgctg gtaaagacag gcttatttat aaacttcaac agaccgacag
    30841 ttcttctcgc tataccaatg gtactcaagg tacggcgtgg acattaatta tggaaaatcc
    30901 tcttaaggga tatggctacg gcgatgatat ttaccatgca atatataata agcgtgttgt
    30961 agattttccg tcatggaagt tcaggcaatc cattgggcca cacaacgttg ttttgtcaat
    31021 ttggtttgca gcgggtttgg ctggactact cgctttactt tatctgtatg gctctattat
    31081 caaagagaca gctaatgcaa cgtttaaaac agttgtcgtc actccttata atggtcaatt
    31141 actactattt ttaacgcttg taagctttta tattattcga ggtaacttcg aggaagttga
    31201 tctcaaacca attggcttga ttgttggttt actgttagca atgcggaata aataaaaaaa
    31261 agcctgcctg acattaagtt caggcaggct cttcaaatcc aataattttt aaccaaacca
    31321 gtcttgtatt tgtgcttcaa aacgctgagt aacatgttcc cagctatatt ttgagaaaac
    31381 aaaatttcgg gcatttttag caatttgagc tctgtcagca tccgccaaaa cgcgcttaat
    31441 atccgcgaga atactttcag atgtcatagg ctctgcaagg tgatagcctg taattccttc
    31501 cagaacaaac tcactaattc cacctttttg actggcaagc actggtttac ctgccgccat
    31561 cgcttcaaca gctaccatac aaaaagcttc ttctacctga gaaggaacaa caactaaatc
    31621 tgctaaacgg taatagttat gcatctgctc tggaggctgt ccacccgcca taatgcattg
    31681 cgctccaata gctttcgctg catccagaac ttttttctga tattcagctt tttcgccttt
    31741 tttactggca aaaggatctc cgacaatcac cagtttgagg ttatcttgta tcttattcag
    31801 ctgattaaaa gcctccataa gcatcaggca acctttatct ggtgatatcc ttcctgcaaa
    31861 taataacacg gtatcatttg catcaatgtt cagtttctgc ctcaaatctt cagtattatt
    31921 ttgttcatac gattcagaac aaaaaccatt aggcacaata gcaatatttg catcaggcat
    31981 tttttccgaa tagaaatcga aaagaaactg gctaggaaca attatctttg catttttgtc
    32041 taactcacct ggctcgaaag cattatgaag atgcataact agctgcgcgt gagggcttct
    32101 gctacgaatc tgtttataca gcttcatgct attgtggata acaataacag agtctttcgg
    32161 atcagtgttt ttaggttggg tatttaaaat acgctgagaa tatggcacag gatcaagtcg
    32221 agtccacttt tggaaaagtc gtttatagac tcgactaaaa ccaatgtagt gaatatcaca
    32281 gtgatcattt acttttgtgt aggttgggta accttcgttt cgaatacagg cgatagttac
    32341 tggaatcgaa agtctttttg cgacctgata aatccatgtt tcaaccgctg cagctccttt
    32401 tggcggtata gaaaatattg gtgtgacggt aaatattatt tttttaatca ttattagcca
    32461 actccaatat aatttataac acgtaataaa cacatataaa atattagctt attttttcat
    32521 aaacacacgg ctcttcaatt tcggatattt tcata
//
LOCUS       DACAOP010000047        31759 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.047, whole genome shotgun sequence.
ACCESSION   DACAOP010000047 DACAOP010000000
VERSION     DACAOP010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31759
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.047"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(250..2823)
                     /gene="clpB"
                     /locus_tag="IT892_002452"
     CDS             complement(250..2823)
                     /gene="clpB"
                     /locus_tag="IT892_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAP3135660.1"
                     /translation="MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGG
                     SVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGDVQPSQDLVRVLNLCDKLAQKRG
                     DNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
                     LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILF
                     IDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ
                     KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAID
                     LIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSD
                     KERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPE
                     LEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQEL
                     HHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFD
                     SDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKA
                     HPDVFNILLQVLDDGRLTDGQGKTVDFRNTVVIMTSNLGSDLIQERFGELDYAHMKEL
                     VLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDE
                     ALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAV
                     Q"
     gene            complement(2953..3684)
                     /gene="pgeF"
                     /locus_tag="IT892_002453"
     CDS             complement(2953..3684)
                     /gene="pgeF"
                     /locus_tag="IT892_002453"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphenol oxidase"
                     /protein_id="HAP3135661.1"
                     /translation="MSKLIVPQWPLPKGVAACSSTRIGGVSLPPYDSLNLGAHCGDNP
                     DHVEENRKRLFAAGHLPSKPVWLEQVHGKDVLKLTGEPYASKRADASYSNTPGTVCAV
                     MTADCLPVLFCNRAGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPR
                     AFEVGAEVREAFMAVDAKASTAFIQHGDKYLADIYLLARQRLANVGVEQIFGGNRCTY
                     TENETFFSYRRDKTTGRMASFIWLI"
     gene            complement(3681..4661)
                     /gene="rluD"
                     /locus_tag="IT892_002454"
     CDS             complement(3681..4661)
                     /gene="rluD"
                     /locus_tag="IT892_002454"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HAP3135662.1"
                     /translation="MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQR
                     VLVNGKVCDKPKEKVLGGEQVAINAEIEEEARFEPQDIPLDIVYEDEDIIVINKPRDL
                     VVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
                     SLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHF
                     RVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDR
                     QALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDWL"
     gene            4796..5533
                     /gene="bamD"
                     /locus_tag="IT892_002455"
     CDS             4796..5533
                     /gene="bamD"
                     /locus_tag="IT892_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HAP3135663.1"
                     /translation="MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQ
                     DGNWRQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFIRLNPTH
                     PNIDYVMYMRGLTNMALDDSALQGFFGVDRSDRDPQHARAAFSDFSKLVRGYPNSQYT
                     TDATKRLVFLKDRLAKYEYSVAKYYTERGAWVAVVNRVEGMLRDYPDTQATRDALPLM
                     ENAYRQMQMNAQAEKVAKIIAANSSNT"
     gene            5804..6145
                     /gene="raiA"
                     /locus_tag="IT892_002456"
     CDS             5804..6145
                     /gene="raiA"
                     /locus_tag="IT892_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAP3135664.1"
                     /translation="MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKE
                     PQGFVADATINTPNGVLVASGKHEDMYTAINELINKLERQLNKLQHKGEARRAATSVK
                     DANFVEEVEEE"
     gene            6249..6296
                     /locus_tag="IT892_002457"
     CDS             6249..6296
                     /locus_tag="IT892_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135665.1"
                     /translation="MKHTPFFFAFFFTFP"
     gene            6395..7555
                     /gene="pheA"
                     /locus_tag="IT892_002458"
     CDS             6395..7555
                     /gene="pheA"
                     /locus_tag="IT892_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydratase"
                     /protein_id="HAP3135666.1"
                     /translation="MTSENPLLALREKISALDEKLLALLAERRELAVEVGKAKLLSHR
                     QVRDIDRERDLLERLITLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNKINPY
                     SARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFADIFNQVETGQADYAVVPIEN
                     TSSGAINDVYDLLQHTSLSIVGEMTLTIDHCLLVSGTTDLSTINTVYSHPQPFQQCSK
                     FLNRYPHWKIEYTESTSAAMEKVAQAKSPHVAALGSEAGGTLYGLQVLERIEANQRQN
                     FTRFVVLARKAINVSDQVPAKTTLLMATGQQAGALVEALLVLRNHNLIMTRLESRPIH
                     GNPWEEMFYLDIQANLESAEMQKALKELGDITRSMKVLGCYPSENVVPVDPT"
     gene            complement(7598..8719)
                     /gene="tyrA"
                     /locus_tag="IT892_002459"
     CDS             complement(7598..8719)
                     /gene="tyrA"
                     /locus_tag="IT892_002459"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /protein_id="HAP3135667.1"
                     /translation="MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPI
                     YVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVV
                     IVGGGGQMGRLFEKMLTLSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIG
                     KLPPLPKDCILVDLASVKNGPLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGR
                     KPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQ
                     LLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELLEQG
                     DKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRH"
     gene            complement(8730..9800)
                     /gene="aroF"
                     /locus_tag="IT892_002460"
     CDS             complement(8730..9800)
                     /gene="aroF"
                     /locus_tag="IT892_002460"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroF"
                     /protein_id="HAP3135668.1"
                     /translation="MQKDALNNVHITDEQVLMTPEQLKAAFPLSLQQEAQIADSRKTI
                     SDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTT
                     VGWKGLINDPHMDGSFDVEAGLQIARKLLLELVNMGLPLATEALDPNSPQYLGDLFSW
                     SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQ
                     VALLQTQGNPDGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDY
                     RRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWE
                     MTDALLREIHQDLNGQLTARVA"
     gene            10010..10375
                     /locus_tag="IT892_002461"
     CDS             10010..10375
                     /locus_tag="IT892_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2799 domain-containing protein"
                     /protein_id="HAP3135669.1"
                     /translation="MMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISG
                     STIKDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQ
                     LHEVWQKGADENASTIRLN"
     gene            10525..11043
                     /locus_tag="IT892_002462"
     CDS             10525..11043
                     /locus_tag="IT892_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4154 domain-containing protein"
                     /protein_id="HAP3135670.1"
                     /translation="MRFSHRLFLLLILLLTGAPILAQEPSDVAKNVRMMVSGIVSYTR
                     WPALSGPPKLCIFSSSRFSTALQENAATSLPYLPVIIHTQQEAMISGCNGFYFGNESP
                     TFQMELTEQYPSRALLLIAEQNTECIIGSAFCLIIHNNDVRFAVNLDALSRSGVKVNP
                     DVLMLARKKNDG"
     gene            11033..12259
                     /gene="dgcN"
                     /locus_tag="IT892_002463"
     CDS             11033..12259
                     /gene="dgcN"
                     /locus_tag="IT892_002463"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcN"
                     /protein_id="HAP3135671.1"
                     /translation="MMDNDNSLNKRPTFKRALRNISMTSIFITMMLIWLLLSVTSVLT
                     LKQYAQKNLALTAATMTYSLEAAVVFADGSAATETLAALGQQGQFSTAEVRDKQQNIL
                     ASWHYTRKDPGDTFSNFISHWLFPAPIVQPIRHNGETIGEVRLTARDSSISHFIWFSL
                     AVLTACILLASGIAITLTRHLHKGLVEALKNITDVVHDVRSNRNFSRRVSEERIAEFH
                     RFALDFNSLLDEMEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNSSDA
                     RKTSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFGGLQHKAYRLGGDEFAMV
                     LYDVQSESEVQQICSALTQIFNRPFDLHNGHQTTMTLSIGYAMTIAHASAEKLQELAD
                     HNMYQAKHQRAEKLVR"
     gene            12275..12757
                     /locus_tag="IT892_002464"
     CDS             12275..12757
                     /locus_tag="IT892_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HAP3135672.1"
                     /translation="MIKHLVAPLIFTSLVLTGCQSPQGKFTPEQVVAMQSYGFTESAG
                     DWSLGLSDAILFAKNDYKLLPESQQQIQTMAAKLASTGLTHARMDGHTDNYGEDSYNE
                     GLSLKRANVVADAWAMGGKIPRSNLTTQGLGKKYPIASNKTAQGRAENRRVAVVITTP
                     "
     gene            complement(12834..13181)
                     /gene="rplS"
                     /locus_tag="IT892_002465"
     CDS             complement(12834..13181)
                     /gene="rplS"
                     /locus_tag="IT892_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012768745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAP3135673.1"
                     /translation="MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFE
                     GVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRE
                     RTGKAARIKERLN"
     gene            complement(13223..13990)
                     /gene="trmD"
                     /locus_tag="IT892_002466"
     CDS             complement(13223..13990)
                     /gene="trmD"
                     /locus_tag="IT892_002466"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAP3135674.1"
                     /translation="MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHD
                     RHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSEL
                     ATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVL
                     GHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPSVLLSGNHAEIRRWRLKQSLGRTWL
                     RRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA"
     gene            complement(14021..14569)
                     /gene="rimM"
                     /locus_tag="IT892_002467"
     CDS             complement(14021..14569)
                     /gene="rimM"
                     /locus_tag="IT892_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAP3135675.1"
                     /translation="MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDY
                     QPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLE
                     EGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLD
                     GQVIKKVDLTTRSIEVDWDPGF"
     gene            complement(14588..14836)
                     /gene="rpsP"
                     /locus_tag="IT892_002468"
     CDS             complement(14588..14836)
                     /gene="rpsP"
                     /locus_tag="IT892_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAP3135676.1"
                     /translation="MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIAS
                     EKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA"
     gene            complement(15085..16446)
                     /gene="ffh"
                     /locus_tag="IT892_002469"
     CDS             complement(15085..16446)
                     /gene="ffh"
                     /locus_tag="IT892_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAP3135677.1"
                     /translation="MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVA
                     LPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAV
                     VLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
                     PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETL
                     FVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVG
                     EKTEALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDF
                     LEQLRQMKNMGGMASLMGKLPGMGQIPDNVKLQMDDKVLVRMEAIINSMTMKERAKPE
                     IIKGSRKRRIAAGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGF
                     PGR"
     gene            16538..17404
                     /locus_tag="IT892_002470"
     CDS             16538..17404
                     /locus_tag="IT892_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311501.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HAP3135678.1"
                     /translation="MQRLEQRSPDAILLLFLIAQTVDITMPVFALLALVAYSVSLALI
                     VPGLLQKNGGWRRMAIISAVIALVCHAIALEARILPDGDSGQNLSLLNVGSLVSLMIC
                     TVMTIVASRNRGWLLLPIVYAFALINLALATFMPNEYITHLEATPGMLVHIGLSLFSY
                     ATLIIAALYALQLAWIDYQLKNKKLAFNQEMPPLMSIERKMFHITQIGVVLLTLTLCT
                     GLFYMHNLFSMENIDKAVLSIVAWFVYIVLLWGHYHEGWRGRRVVWFNVAGAVILTLA
                     YFGSRIVQQLIS"
     gene            17425..18711
                     /locus_tag="IT892_002471"
     CDS             17425..18711
                     /locus_tag="IT892_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026171.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP3135679.1"
                     /translation="MEHISTTTLIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQ
                     GNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLT
                     FVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIK
                     TDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKMTVDDIMVPRSEIIGID
                     INDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKETMLRAA
                     DEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMS
                     PTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGT
                     RVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE"
     gene            complement(18766..19359)
                     /gene="grpE"
                     /locus_tag="IT892_002472"
     CDS             complement(18766..19359)
                     /gene="grpE"
                     /locus_tag="IT892_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAP3135680.1"
                     /translation="MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKI
                     ANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSL
                     DRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
                     ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA"
     gene            19482..20360
                     /gene="nadK"
                     /locus_tag="IT892_002473"
     CDS             19482..20360
                     /gene="nadK"
                     /locus_tag="IT892_002473"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HAP3135681.1"
                     /translation="MNNHFKCIGIVGHPRHPTALTTHEMLYRWLYTKGYEVIVEQQIA
                     HELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLT
                     DLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI
                     EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSA
                     RPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS
                     YFNTLSTKLGWSKKLF"
     gene            20446..22107
                     /gene="recN"
                     /locus_tag="IT892_002474"
     CDS             20446..22107
                     /gene="recN"
                     /locus_tag="IT892_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAP3135682.1"
                     /translation="MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGL
                     CLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGR
                     SRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMT
                     ARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLA
                     NSGQLLTTSQNALAVMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQ
                     IAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQ
                     QLDDQADSQETLALAVTKHHQQALETAHALHLQRQHYANELAQLITDSMHALSMPHGQ
                     FTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARK
                     METPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHYFVSKE
                     TDGAMTETHMQSLDKKARLQELARLLGGSEVTRNTLANAKELLAA"
     gene            22256..22597
                     /gene="bamE"
                     /locus_tag="IT892_002475"
     CDS             22256..22597
                     /gene="bamE"
                     /locus_tag="IT892_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417107.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HAP3135683.1"
                     /translation="MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVS
                     KIRVGMTQQQVAYALGTPLMSDPFGTNTWFYVFRQQPGHEGVTQQTLTLTFNSSGVLT
                     NIDNKPALSGN"
     gene            complement(22659..22949)
                     /locus_tag="IT892_002476"
     CDS             complement(22659..22949)
                     /locus_tag="IT892_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417108.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HAP3135684.1"
                     /translation="MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRT
                     DIDLTKNKVGIYSRPAKLSDSVHDGDRVEIYRPLIADPKELRRQRAEKSANK"
     gene            complement(22939..23415)
                     /gene="ratA"
                     /locus_tag="IT892_002477"
     CDS             complement(22939..23415)
                     /gene="ratA"
                     /locus_tag="IT892_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin RatA"
                     /protein_id="HAP3135685.1"
                     /translation="MILFVGFLLMEIVMPQISRTALVPYSAEQMYQLVNDVQSYPQFL
                     PGCTGSRILESTPGQMTAAVDVSKAGISKTFTTRNQLTSNQSILMNLVDGPFKKLIGG
                     WKFTPLSQEACRIEFHLDFEFTNKLIELAFGRVFKELAANMVQAFTVRAKEVYSAR"
     gene            23547..24029
                     /gene="smpB"
                     /locus_tag="IT892_002478"
     CDS             23547..24029
                     /gene="smpB"
                     /locus_tag="IT892_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAP3135686.1"
                     /translation="MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSL
                     RAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYG
                     RVNREGYTVVALALYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
                     "
     gene            24244..24606
                     /gene="ssrA"
                     /locus_tag="IT892_002479"
     tmRNA           24244..24606
                     /gene="ssrA"
                     /locus_tag="IT892_002479"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(24767..29341)
                     /locus_tag="IT892_002480"
                     /pseudo
     CDS             complement(24767..29341)
                     /locus_tag="IT892_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311542.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(29406..29525)
                     /locus_tag="IT892_002481"
     CDS             complement(29406..29525)
                     /locus_tag="IT892_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP3135687.1"
                     /translation="MPHSYAEYHHFIMMSLMSGEHNTLALSLQDESPGLVPVG"
     gene            complement(29679..29822)
                     /locus_tag="IT892_002482"
     CDS             complement(29679..29822)
                     /locus_tag="IT892_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000264669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135688.1"
                     /translation="MWHLVVLLEELCKRGINFRALAQSIFPQQWGDECCKSKTICDLK
                     VIV"
     gene            complement(30276..31730)
                     /locus_tag="IT892_002483"
     CDS             complement(30276..31730)
                     /locus_tag="IT892_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135689.1"
                     /translation="MLVSKSNEINTSTFINSGSCNERKSSKSMELLAYSIIKLICKEA
                     ASGTYNGALEILQKMMSECKYHEGNAFVIMGAGEQLKRIKYDANENKLKVYNVHFDNN
                     QELVADGEPDVVFLKKTVWEDLLVKLKLENKENAVSEINLSSNKNNVDQFIECAKRNE
                     QTLFGNIRKSDFHVASLQPGRTRSVISETPPNDCMESHNLYENHTDTVSTVTKNSQQV
                     KGHYGDKLKEMQLFLNQMSNALQQDSSLLESKEHTIDIQEKTNKFVQHFQRVLFDKNG
                     RSSEFLLNFYECCYKFLPRAQPQDKIDSYNSALQAFSIFCSSTLTHNNVGFNFKLFPE
                     VKLSGGELETVFKYKNGNFVWEIARIKITLPKEEGGLYNLRGLDFKGCFFSGQNFSNY
                     DIQYVNWGTSLFDLDTPCIFNAPAYNKSNEKSLERVSENGLSGVLSDRNKKIKLITGV
                     APFDDILFMDDDFDDNSPDDGPVENSPVVNSPLV"
BASE COUNT         7999 a         8295 c         7267 g         8198 t
ORIGIN      
        1 cccgctacag agtcaagcat ttttttgctt ttctctgttg agattctcag gagaacctcg
       61 ctgacccggc ggcgtgcttg ccgttgttcc gtgtcagtgg tggcgcatta tagggagtta
      121 ttccggcctg acaagcgaaa aatataaaaa ctttatcgtt cgctcatttt tcaggcaaaa
      181 catcttaaat atagtctttt ccgtctaact tatagacaaa aacgagcccc gaagggctcg
      241 ttttatcatt tactggacgg cgacaatccg gtcttcatta acttccaggc gaatcacttt
      301 acccggaacc aattcaccag acagtatttg ctgtgccagc gggttttcaa tctgctgctg
      361 aattgcacgt ttcagaggac gtgcgccata gaccggatcg taaccgttct cgctcagcag
      421 tttcagcgcc tcgtcagaaa tgtggatttc ataaccacgt tcttccagac gtttatacag
      481 acgtttcaac tgaatctgcg caatcgacgc aatgtgctgt tcacccagcg gatggaagac
      541 caccacttca tcgatacggt taatgaattc cggacggaag ttatggctaa ccacaccgag
      601 caccagctct ttcatgtgcg cataatccag ttcaccgaag cgttcctgaa tcagatcgga
      661 accgaggtta gaggtcataa tgacgaccgt attacggaag tcgaccgttt tcccctgccc
      721 gtcagtcaga cgcccatcat ccagtacctg caacagaatg ttgaagacat ccggatgcgc
      781 tttttccact tcatccagca ggataacgga atacggacga cgacgcacag cttcggtcag
      841 gtagccacct tcttcataac caacatatcc cggaggcgca ccaaccagac gagacaccga
      901 atgtttctcc ataaactcgg acatatcgat acggaccatc gcctcgtcgc tatcaaacat
      961 aaagttcgcc agcgccttac aaagctcagt tttccccaca cccgttgggc cgaggaacag
     1021 gaatgaacca atcgggcgat ttggatccgc cagccccgca cggctacgac gaatagcgtt
     1081 agataccgca tcaaccgctt cgttctgacc aataacgcga tggtgcagct cttgctccat
     1141 acgcagcagt ttttcgcgct cgctttccat catgcgagaa accggaatcc ccgtccaacg
     1201 cgccagcact tcagcaattt cggcgtcggt cactttatta cgcaacagac gcatagtttt
     1261 gccttcgagc tgcgttgcgg cttccagttg cttttccagt tccgggattt tgccgtattg
     1321 cagttcagac atccgcgcca ggtcacccac acggcgagcc tgttcaatag cgattttcgc
     1381 ctgttccagt tccgctttaa tggtctgtgt accagaaagc gatgctttct ctgctttcca
     1441 ctcttcttct aactcggagt actgacgttc tttgtcgctc agttcttcgt tgagcatatc
     1501 caggcgtttt ttactggctt catcagactc tttcattaac gcctgttgtt ccagtttgag
     1561 ctggataata cgacgatcga gtcggtcgag ttcttctggt tttgagtcaa tctgcatacg
     1621 aatgctggat gctgcttcat cgatcaggtc gatggcttta tccggcagct gacggtcagc
     1681 aatgtagcga tgagacaacg tcgccgctgc aacaattgcc gggtcagtaa tttgcacatg
     1741 gtggtgcagt tcgtaacgtt cttttaagcc acgcagaata gcaatggtgt cttcaacaga
     1801 aggctcggca acaaacactt tctggaaacg acgttccagc gcagcatctt tttcgatgta
     1861 ctggcgatat tcgtcaagcg tcgtggcacc tacgcagtgc aattcaccac gcgccagcgc
     1921 cggtttcagc atgtttccgg cgtccattgc gccatcggct ttacccgcgc cgaccatggt
     1981 atgtaattcg tcgataaaca ggatgacgtt gccttcctgt ttggcaagat cgttaagcac
     2041 gccttttaaa cgttcttcaa actcaccgcg atatttcgcc ccagccacca gcgcgcccat
     2101 atccagcgcc agtacgcggc ggcctttcaa cccttccggc acttcgccgt tgataatacg
     2161 ctgcgccaga ccttcaacga tggcagtttt accgacgccg ggttcaccaa tcagtactgg
     2221 gttattttta gtacgacgtt gcagcacctg aatggtacgg cgaatttctt catcacgacc
     2281 aatcaccgga tcgagtttgc cctgttcggc tcgttcggta aggtcgatgg tatatttttt
     2341 caaagcctga cgttggtctt cagcaccttg atcgttcacg ctttcacctc cacgcatttg
     2401 ttcaatcgct tgagtaatgt tggcggtggt cgcccctgct gctttcagga tgtcggccag
     2461 cgtgccgcga gactcaagtg ccgccagaac gaacagttct gacgagataa agttatcacc
     2521 acgtttttgc gccagcttgt cgcaaagatt aagaacgcgc accagatcct gtgatggctg
     2581 gacatcacca ccagtacctt caacctgcgg taaacgattt aatgcctgat tgatatctgt
     2641 gcgcaactgg ccagcattta tgccagcgga tgttaataaa ggactaaccg aacccccttc
     2701 ctgattcagc agggcgctca ttaaatgaag tggttcgata aattggttgt cgtgcccgag
     2761 tgcaagtgat tgggcatcgg caagagcaag ctggaattta ttagtaagac gatccagacg
     2821 cataactcct cccataacgg atcaaagttg ctactggaga ttaaatgagg tcatccctca
     2881 attattcaag gttattgacc agattaatgt gaaaagaaaa tcacgcgtac cggatcgtct
     2941 tgattcttta ggttatatca gccaaatgaa acttgccata cgaccagtgg tcttgtcgcg
     3001 acgataagag aagaaagtct cattttccgt atatgtacaa cggttgccgc cgaaaatttg
     3061 ttcgacaccg acgttcgcca gacgctgccg ggcaaggaga taaatatccg ccagatactt
     3121 atcaccatgc tgaatgaaag ctgtactcgc tttggcgtct actgccataa acgcctcgcg
     3181 aacctccgcc cccacttcaa acgcgcgtgg accaattgcc ggccctaacc aggcgagaat
     3241 attttccgga ttatcagcaa aacaggaaac cgtctcttcc agcacgcctg cgcacagtcc
     3301 acgccagcca gcatgagcgg cggcgacttc cgttcccgct cgattgcaaa acagcacggg
     3361 gaggcagtcg gcagtcatca ctgcgcaaac cgtgcccggc gtgttgctat aagaggcatc
     3421 tgctcgtttt gaggcataag gttcgccagt aagcttaagc acatctttgc cgtgtacctg
     3481 ctcaagccag accggttttg aaggcaaatg gcccgcagca aaaagtcgct tgcgattctc
     3541 ctcaacgtga tccgggttat cgccacaatg ggcaccgagg ttgagcgagt catacggggg
     3601 caagctcacg ccgccgatac gagtggagct acaggccgca acaccttttg gcagcggcca
     3661 ctgcgggaca atcagcttac tcataaccag tccacttcat ccttatgctc ttcgaaatcg
     3721 gcgcgcatca cctcaatcag ctccaccata tcttgtggaa taggcgcatg ccattccatt
     3781 tcgatgccgg agatcgggtg ataaagacgc agcatggttg catgaagcgc ctggcggtca
     3841 aacttacgca gcgtggagat aaacgcttcc gaagcacctt ttggcggacg cggacggcca
     3901 ccataaaccg gatcgcccac cagcggatga gtgatatggg ccatatgcac gcggatctgg
     3961 tgcgtacgtc cggtttccag acgcaaccgc agacgcgtgt gcacacggaa gtgttccatg
     4021 atgcgatagt gagtgaccgc cggtttaccc atcggatgca ccgccatgtg agtacgtttg
     4081 gtcgggtggc ggctgattgg ttcatctact gtaccgccag cggtcatatg accaattgcc
     4141 accgcttcat actcacgagt aatttcacgc cgttgcaaag attcgactaa acgcgtctga
     4201 gccggaacgg tttttgccac aaccatcagg ccggtggtgt ctttatccag acgatggacg
     4261 atgcccgcac gcggtacatc ggcaatgggc ggatagtaat gaagcaacgc attcaatacc
     4321 gtaccatccg ggttacccgc gccaggatgt accaccaggt cgcgtggttt attaatgacg
     4381 atgatatctt catcttcata gacgatatcc agcgggatat cctgcggttc aaaacgcgct
     4441 tcttcttcaa tctcagcgtt gatggccacc tgctcgccac ccaatacttt ttctttcggc
     4501 ttatcacaaa ctttgccgtt aaccagcacg cgctggtcga ggatccattc ttttattcgc
     4561 gaacgtgaat aatccgggaa catttcggcc aaagcctgat ctaagcgttg accgagttgg
     4621 ttttcggaca ccgttgcagt gagctgtact cgttgtgcca tatatactgc ttcttcgttt
     4681 atcgttgggg ttttacggct ttgccgttta atatagtgtg ctattgtagc tggtcttaac
     4741 cgggagcagg aacagagaat ctcccgtatt acattttgag gaaagtcaaa acgtcatgac
     4801 gcgcatgaaa tatctggtgg cagccgccac actaagcctg tttttggcgg gttgctcggg
     4861 gtcaaaggaa gaagtacctg ataatccgcc aaatgaaatt tacgcgactg cacaacaaaa
     4921 gctgcaggac ggtaactgga gacaggcaat aacgcaactg gaagcgttag ataatcgcta
     4981 tccgtttggt ccatattcgc agcaggtgca gctggatctc atctacgcct actataaaaa
     5041 cgccgatttg ccgttagcgc aggctgccat cgatcgtttt attcgcctta acccgaccca
     5101 tccgaatatc gattatgtca tgtacatgcg tggcctgacc aatatggcgc tggatgacag
     5161 tgcgctgcaa gggttctttg gcgttgaccg tagcgatcgc gatcctcaac atgctcgagc
     5221 tgcgtttagt gacttttcca aactggtgcg cggctatccg aacagtcagt acaccaccga
     5281 tgccaccaaa cgtctggtat tcctgaaaga tcgtctggcg aaatatgaat actccgtggc
     5341 caagtactat acagaacgtg gcgcatgggt tgccgtcgtt aaccgcgtag aaggcatgtt
     5401 gcgcgactac ccggataccc aggctacgcg tgatgcgctg ccgctaatgg aaaatgcata
     5461 ccgtcagatg cagatgaatg cgcaagctga aaaagtagcg aaaatcatcg ccgcaaacag
     5521 cagcaataca taacagaaat ctgaaacaca aaacggcagc ccttgagctg ccgttttttt
     5581 attctgttag ttgtgaaact gaagcgattt agtcactatc gatctcatca aatatggctc
     5641 gctttgagat attcctcaag taaaaaaaca cctcttcctg cgatttctca caaaaaaact
     5701 tcgttgacaa aaagtgacaa aattatgaga tttccatcac acattttgac atcaggaacg
     5761 gtatgctgaa ttcaccaaga cgggaagaca agaggtaaaa tttatgacaa tgaacattac
     5821 cagcaaacaa atggaaatta ctccggccat ccgccaacat gtcgcagacc gtctcgccaa
     5881 actggaaaaa tggcaaacac atctgattaa tccacatatc attctgtcca aagagccaca
     5941 agggtttgtt gctgacgcca caatcaatac acctaacggc gttctggttg ccagtggtaa
     6001 acatgaagat atgtacaccg caattaacga attgatcaac aagctggaac ggcagctcaa
     6061 taaactgcag cacaaaggcg aagcacgtcg tgccgcaaca tcggtgaaag acgccaactt
     6121 cgtcgaagaa gttgaagaag agtagtcctt tatattgagt gtatcgccaa cgcgccttcg
     6181 ggcgcgtttt ttgttgacag cgtgaaaaca gtacgggtac tgtactgaag tcacttaagg
     6241 aaacaaacat gaaacacaca ccgtttttct tcgcattctt ttttaccttc ccctgaatgg
     6301 gaggcgtttc gtcgtgtgaa acagaatgcg aagacgaaca ataaggcctc ccaaatcggg
     6361 gggccttttt tattgataac aaaaaggcaa cactatgaca tcggaaaatc cattactggc
     6421 gctgcgagag aaaatcagcg cgctggatga aaaattatta gcattactgg cagagcggcg
     6481 cgaactggcc gtcgaggtgg gaaaagccaa actgctctcg catcgccagg tacgtgatat
     6541 tgatcgtgaa cgcgatttac tggaaagatt aattacgctc ggtaaagcgc accatctgga
     6601 cgcccattac attactcgcc tgttccagct catcattgaa gattccgtat taactcagca
     6661 ggctttgctc cagcaacatc tcaataaaat taatccgtac tcagcacgca tcgcttttct
     6721 cggccccaaa ggttcttatt cccatcttgc ggcgcgccag tatgctgccc gtcactttga
     6781 gcaattcatt gaaagtggct gcgccaaatt tgccgatatt tttaatcagg tggaaaccgg
     6841 ccaggccgac tatgccgtcg taccgattga aaataccagc tccggtgcca taaatgacgt
     6901 ttacgatctg ctgcaacata ccagtttgtc gattgttggc gagatgacgt taactatcga
     6961 ccattgtttg ttggtctccg gcactactga tttatccacc atcaatacgg tctacagcca
     7021 tccgcagcca ttccagcaat gcagcaaatt ccttaatcgt tatccgcact ggaagattga
     7081 atataccgaa agtacgtctg cggcaatgga aaaggttgca caggcaaaat caccgcatgt
     7141 tgctgcgttg ggaagcgaag ctggcggcac tttgtacggt ttgcaggtac tggagcgtat
     7201 tgaagcgaat cagcgacaaa acttcacccg atttgtggtg ttggcacgta aagccattaa
     7261 cgtgtctgac caggttccag cgaaaacgac gttgttaatg gcgaccgggc aacaagctgg
     7321 tgcgctggtt gaagcgttgc tggtactgcg caaccacaat ctgattatga cccgtctgga
     7381 gtcacgcccg attcacggta atccatggga agagatgttt tatctggata ttcaggccaa
     7441 tcttgaatca gcggaaatgc aaaaagcatt gaaagagtta ggggacatca cccgttcgat
     7501 gaaggtattg ggctgttacc caagtgagaa cgtagtgcct gttgatccaa cctgatgaaa
     7561 aggtgccgga tgatgtgaat cacccggcac tggattatta gtggcggttg tcattcgcct
     7621 gacgcaataa cacgcggctt tcactctgaa aacgctgtgc gtaatcgccg aaccagtgct
     7681 ccaccttgcg gaaactgtca ataaacgcct gcttatcgcc ctgctccagc aactcaatcg
     7741 cctcgccgaa acgcttatag taacgtttga ttaacgccag attacgctct gacgacataa
     7801 taatgtcggc ataaagctgc ggatcctgag caaacagtcg cccaaccatc gccagttcaa
     7861 ggcggtaaat cggcgaagag agcgccagaa gttgctcaag ctgaacattt tcttctgcca
     7921 ggtgcagccc ataagcaaaa gtagcaaagt ggcgcagagc ctgaataaac gccatattct
     7981 gatcgtgctc gacagcgcta atacgatgca gccgagcgcc ccagacctga atttgctcca
     8041 gaaaccattg gtatgcttcc ggcttacgtc catcacacca gaccacaact tgctttgcca
     8101 ggctaccgct gtccggaccg aacatcgggt gtagccccag caccggacca tcatgcgccg
     8161 ccagcatggc ctgtaatggc ccatttttca ctgatgccag atcgaccaga atacaatctt
     8221 tcggtaaagg cggtaatttg ccgataactt gctcagtaac gtggattggc acactaacaa
     8281 tcaccattcc ggcatcggca acaatatcag ccgctcgatc ccagtcatgt tgctccagaa
     8341 tccgcacctg ataacccgat agtgtcagca tcttctcgaa caggcgtccc atctgaccgc
     8401 caccgccgac gataaccacc ggacgcagtg acggacaaag tgttttaaat cctttgtcat
     8461 tttcactgga gtaagattca cgcatcaccc gacgcaaaac atcctcaatc agatctggcg
     8521 gtacacccag agcttccgcc tctgcacgac gcgaggccaa catagatgcc tcgcgctccg
     8581 gcacataaat aggcagtcca aagcggcttt tcacctcgcc cacttcagca accagttcca
     8641 gacgcttcgc taataaattc agcagcgctt tatcgacttc atcaatttga tcgcgtaatg
     8701 cggtcaactc agcaaccata ataaacctct taagccacgc gagccgtcag ctgcccgttc
     8761 agatcctgat gaatttcacg cagcaaggca tcggtcattt cccaactaat gcaggcatcg
     8821 gttacggata caccgtattt catttcactg cgcggttgct cggaagactg attgccctcg
     8881 tggatattac tttcgatcat cagaccaata attgagcgat tgccatcttt gatttgagca
     8941 accacggatt ctgccaccgc aggctgacgg cgataatctt tattggaatt accgtggctg
     9001 caatctacca tcagagacgg gcgcagtccc gcctgttcca tctctttttc acattgcgca
     9061 acatccgcag ggctatagtt cggcgcttta ccaccgcgca ggatcacatg cccgtccgga
     9121 ttcccctgag tttgtagcaa cgccacctgc cctgcctggt taatgccaac aaaacggtgc
     9181 ggctgggcgg cggcgcgcat agcgttaatt gctgttgcca gactgccgtc ggtgccgttt
     9241 ttaaaaccaa ccggcatgga aagcccggag gccatttcac ggtgagtttg cgattccgtt
     9301 gtacgagcac caattgctga ccagctaaac agatcgccca ggtattgcgg gctatttgga
     9361 tctaacgctt ccgtcgccag tggcagtccc atattcacca gctcaagcag caatttacgc
     9421 gcgatctgca gcccggcttc tacatcaaaa gagccatcca tatggggatc gttaatcaac
     9481 cctttccaac cgacagtggt acggggtttt tcaaaataga cgcgcattac cagatagagg
     9541 ctatcgctga cctctgcggc aagggcttta aatcgacgag catattccag agcagtttcc
     9601 ggatcatgaa tggaacaagg accacatact accaacagac gaggatcgcg cccggcgata
     9661 atatctgaaa tggttttacg cgagtcagca atctgggctt cttgttgcag gcttaatgga
     9721 aaagcggcct tcagttgttc cggagtcatt aaaacctgtt cgtcggtaat atgtacgtta
     9781 ttcagcgcgt ctttttgcat gatggcgatc ctgtttatgc tcgtttgcga tagttgatcc
     9841 tcagcgagga tgacgtaacg ataacacata aagtaaagtt ttcaatccat atttcgtaca
     9901 tttttattta cacaagcaat ttattcgcgc ttttgacgct tattttcgta caaataaatt
     9961 tacacctcct ttaaaaacaa tccgctatgc tttgaaaaag gagaaagaaa tgatgaaaaa
    10021 gtttattgcc cccttgttgg ctttactggt tagcggatgt cagattgatc cttatactca
    10081 cgcgccaacc ttgaccagca ccgactggta tgatgtcggt atggaagatg cgatatcggg
    10141 cagcaccata aaagatgacg atgcatttag cgattcacag gcggatcgcg gtctatacct
    10201 taaaggatat gccgaaggac aaaagaaaac ttgtcagacc gattttactt atgcccgagg
    10261 actttccggt aaaagctttc ctgccagctg caacaatgtt gaaaatgcca gccaactgca
    10321 tgaagtatgg caaaaagggg ctgatgaaaa tgccagcaca atacgattaa attaattaaa
    10381 cccccgcaaa taaattaagc atgagatttt gctcattgtg ttttatttct cacattgatg
    10441 acgaccgcat gaaagaatga tattttaatg agcattctga aaaaatatcg atgcatttcg
    10501 agcgaagatg gtgaggatcc ctgaatgcgt ttttctcacc gactgttctt actgctgatt
    10561 ctcctgctga cgggagcacc aatactcgct caggaacctt ctgacgttgc gaaaaacgtg
    10621 cgtatgatgg tttccggtat tgtcagttac acccgctggc ctgcgctatc agggccacca
    10681 aagttatgta tcttttcatc ttcacgtttt agtaccgccc tacaagagaa tgccgcgaca
    10741 tctttgcctt atctgcctgt catcattcac actcaacaag aggcgatgat ttcaggctgc
    10801 aatggttttt attttggcaa cgagtcaccg acattccaga tggaattaac cgaacaatat
    10861 ccgtcaaggg cgttattatt aattgccgaa caaaataccg agtgcattat tggtagcgcc
    10921 ttttgtctga tcatccacaa taatgacgtc agatttgccg taaacctgga tgccttatcg
    10981 cgtagcggag taaaggtcaa cccggatgtc ttaatgctcg cacggaagaa aaatgatgga
    11041 taacgataat tctcttaata agcgccccac gtttaaaaga gcattacgca acatcagtat
    11101 gaccagcata tttatcacta tgatgctgat ctggttgctg ctttccgtga cctcggtgct
    11161 gaccctgaaa cagtacgcgc aaaaaaacct ggcactgaca gcagcaacaa tgacttacag
    11221 tctggaagca gcggtcgttt ttgccgatgg ctctgcagca actgaaacac tggcagcgct
    11281 ggggcagcaa ggccaatttt caactgcaga agtgcgtgat aagcagcaaa atattctggc
    11341 atcctggcat tacacccgta aggatccagg cgatactttc agtaatttca taagccactg
    11401 gctcttccct gcccccatcg ttcagccgat tcgtcacaat ggtgaaacca ttggcgaagt
    11461 tcgcttaacc gctcgcgaca gttcaatcag ccatttcatc tggttttcgc tcgctgtcct
    11521 gaccgcctgc attctgctgg catcaggcat cgcaattacc ctcacccgcc atttgcacaa
    11581 gggtctggtt gaagcgttaa aaaacatcac cgatgtcgta catgatgtgc gttccaaccg
    11641 caatttttcc cgacgagttt cggaagaacg tatcgcagag tttcaccgct tcgctctcga
    11701 cttcaacagt ctgctggatg aaatggaaga gtggcagctt cgtttacagg ccaaaaatgc
    11761 gcagcttcta cgtaccgcac tacatgaccc attaaccggg ctggctaacc gcgcagcgtt
    11821 tcgtagcggt atcaacacgt tgatgaacag ttccgatgcc cgaaaaacgt cggcgttact
    11881 atttcttgat ggcgataatt tcaaatatat caatgatacc tggggtcatg cgacgggcga
    11941 tagagtcttg attgaaatcg caaaacggtt agctgaattt ggcgggctgc aacataaagc
    12001 ataccgcctg ggcggcgatg aattcgcgat ggtgctctat gatgtacagt cggaatctga
    12061 agtgcagcag atatgctcag cactgacaca aatctttaat cgcccgtttg atcttcataa
    12121 tggccatcag accaccatga cattaagcat tggttacgca atgaccattg cgcacgcttc
    12181 tgcggaaaaa ttacaagagc tggccgatca caatatgtat caggccaaac accagcgtgc
    12241 cgaaaagctg gtgagataac aaggatatat cgatatgata aagcacctgg tagcacccct
    12301 gattttcacc tcgctagtac tgactggctg ccagtcccct cagggaaagt ttactcctga
    12361 gcaagtcgtc gctatgcaat cttatggatt tactgaatcc gccggcgact ggtcgctggg
    12421 cttatcagat gccattctgt tcgcaaaaaa tgactacaaa ttgctcccgg aaagccagca
    12481 acagatccaa accatggcag ccaaattggc ctcgacaggg ctaacacatg cccgtatgga
    12541 tggacacacc gataactatg gtgaagacag ttacaacgaa ggcttatcat tgaaacgggc
    12601 gaatgtcgtg gccgatgcat gggctatggg tggaaaaatt ccacgcagca atctcaccac
    12661 acagggttta ggaaaaaaat atcccatagc cagtaacaag accgcccagg gccgcgccga
    12721 gaaccgccgc gtcgcagtgg tgattacaac cccttaaaac acgagcaaac agacaaaaaa
    12781 agggccagcc aattggccag cccttcttaa caggatgtcg cttaagcgaa atcttagtta
    12841 agacgctctt tgatacgagc agccttacca gtacgctcac gcaggtagta cagtttagct
    12901 ttacgaacag caccacgacg tttgacagaa atgctgtcaa ctaccggaga gtgagtctgg
    12961 aagacacgct caacgccttc gccgttggaa attttacgaa cagtgaatgc agagtgcaga
    13021 ccgcggttac gaatagcgat aaccacgccc tcgaatgcct gcagacgttt tttggaacct
    13081 tcaacaaccc atactttcac ttccacggta tcacccggac ggaaggaagg tacgtcctgc
    13141 ttcatctgct cttgttcaag ttgcttaata atgttgctca taatttaatc tcttatcctg
    13201 ggtaaactga tatctcgggg gcttacgcca tcccatcatg tttatgttgc tgttgtgcgt
    13261 gttccgtttt gaactccgcc agcaaccttg cttgctcttc agtcagagcc aggttttcca
    13321 gaagttcagg tcttctaagc caggtacggc ccagcgactg tttcaaacgc cagcgacgta
    13381 tctcggcatg gttgcccgac agtaacactg acggaacttc catcccttct aacacctcag
    13441 gccgcgtata gtgcgggcaa tccagcaatc cttcagcaaa ggaatcttcc gttgccgagg
    13501 cttcatgtcc cagtactccc ggaataaacc gggaaacgga gtcaatcagc gtcattgctg
    13561 gtaactcacc accactgaga acgtaatcgc cgattgacca ttcttcgtca atttcggttt
    13621 ggatcacgcg ctcatctata ccttcgtagc gaccgcacac cagaatcaat ttttgattcg
    13681 ttgccagttc gctgacgccc gcttgatcaa gcttgcgtcc ctgtggtgac agataaatca
    13741 cctttgcgcc ttcacccgcc gcggcttttg ctgcatgaat ggcgtcccgc aaaggttgca
    13801 ccatcattaa catccccggt ccgccgccgt aaggacgatc gtccacggta cggtgccggt
    13861 catgcgtgaa gtcgcgagga ctccagctct ggatgctcag caggccattt ttaactgccc
    13921 ggccagttac cccgtaatcg gtaattgcgc ggaacatttc aggaaacagg ctaattatgc
    13981 caatccacat agcgccgtct tttaccgttt atccggtggt ttaaaaacca ggatcccaat
    14041 ctacttcgat tgaacgagta gtgagatcga ctttcttgat aacctgccca tcgaggaacg
    14101 gtacgagacg ttccttgata ccaaacgcat ctttcaggtt tgccttaatg acgagaacat
    14161 cattagatcc ggtttccatc atatcgacga ctttaccgag atcgtagcct tcagtggtta
    14221 ctacctggca gcccatcagg tctttccagt agtagtcacc ctcttcaagc tgaggcagct
    14281 gcgatgaatc cacgacaatt tcacaattcg tcagtaggtt cgccgcatca cgatcgtcaa
    14341 cgcctttcag cttgatgatc atgtcctgat tgtggtgctt ccagctttcc agctggactt
    14401 gctgccactg acccgccttc tggataaacc agggctgata gtcaaaaatg ctttcggcgt
    14461 cttcggtgga agaaaacact ctgagccacc cacgaatacc gtaagacgaa cccatttttc
    14521 ccaaaacgat gggatcaaca ggtgcttgcg cggtgagttg tttgctcatc atgaccaccg
    14581 tgacagatta agctgctttg tttacttctt tgatcagcgc agcaacgcga tcagaaatag
    14641 ttgcgccctg gccaacccag tgagcgatgc gatccagatc caggcgagtg ccttcttctt
    14701 tttcgctagc gattgggttg aagaaaccaa cgcgctcgat gaagcgaccg ttgcgtgcat
    14761 tacggctgtc agcgacaaca acctggtaga acggacgctt tttagcgccg tgacgtgcta
    14821 aacgaatagt taccataaca tcctcttgtg tgaataaaac aaccggaccc catcgaggaa
    14881 cggagtccgg tgtcatatta aaagcccgaa aattttactc atttttgcgg aaattgcaat
    14941 caacagttgc taactctgct gtaaaaggcc gtcggcggtg cagccagttt ggtgccggag
    15001 tgcgcgcagt caccggagcg tacacgcagt acgtgaggat gacgagcaca ccccggtgcc
    15061 aaaatggcaa acaagccagg ccgattagcg accaggaaat cccggcggca tcatcccttt
    15121 catgcttctc atcatcttcg ccattccgcc cttcttcatt ttcttcatca tgcgctgcat
    15181 gtcgtcgaac tgcttcagaa ggcggttaac gtcctgtacc tgcatcccgc aaccggcggc
    15241 gatacgacgc ttacgtgaac ctttgatgat ttctggctta gcgcgctctt tcatcgtcat
    15301 tgagttgatg atggcttcca tacgcaccag cactttatcg tccatctgca acttgacgtt
    15361 atccgggatc tgccccatgc ccggcagttt gcccatcaag ctggccatgc cgcccatatt
    15421 tttcatctgc cgcagctgct caaggaagtc gttgagatcg aagccgtcgc cttttttcag
    15481 cttgctggct aatttctctg cctgcgcgcg gtcaactttg ctttcgatat cttcgatcag
    15541 cgacagtacg tcgcccatgc cgagaatacg cgacgcgatg cggtccggat ggaacggctc
    15601 cagcgcctca gttttctcgc caacaccgag gaacttgatc ggtttgccag tgatgtgacg
    15661 aatagagagc gccgcaccgc cgcgggcatc gccgtccact ttggtcaaca ctacgccggt
    15721 aagcggtaac gcttcattaa atgcttttgc cgtattggcc gcatcctgac cggtcatggc
    15781 gtcaaccaca aacagggttt caaccgggtt aatcgacgca tggacttgtt tgatctcgtc
    15841 catcatcgct tcgtcaacgt gcagacgacc agcggtatcc accagcagca cgtcgtagaa
    15901 tttcagtttg gcttctttca acgccgcgtt aacaatatca accggcttct gaccaacatc
    15961 agaagggaag aaatcaacgc ccacctgctc agccagcgtc tcaagctgtt tgattgccgc
    16021 cgggcgatag acgtcggcag aaaccaccag cactttcttc ttgtgcttct cgcgcaggaa
    16081 cttaccgagt ttaccaacgc tggttgtttt accggcacct tgcaggcctg ccatcagcac
    16141 gaccgcaggc ggttgcgcag ccaggttcag ggtctggttc tcttcgccca tcgccgcaac
    16201 cagttcgtta cggacgattt tgacgaactc ctgccccggc gtcaggctct tattaacttc
    16261 atgaccaacc gctttctctt ttacgcgatt gataaactca cgcactaccg gcagagcgac
    16321 gtccgcctcc agcagcgcca tgcgcacttc gcgcagcgta tcttttacgt tgtcttcagt
    16381 gaggcgtcca cggccactga tattgcgcag cgtgcgcgac aaacgatcgg ttaaattatc
    16441 aaacattgtc tctcgcctgg ggtggaaacg gttggccgca atcgcgacac atcatcagta
    16501 ttttgccgca gtataacatg aaggcgtctt tgttgttatg caacggttgg agcagcgttc
    16561 acctgacgct atactgcttc tctttcttat tgctcaaact gtcgacatca ctatgcccgt
    16621 ttttgctctg ctcgcgcttg tcgcctactc cgtcagtctt gcgctgattg ttcccggtct
    16681 gctgcaaaaa aacggcggct ggcggcgcat ggctattatt tctgcggtca ttgcgctggt
    16741 ctgccacgca atcgctctgg aagcccgcat cctgcccgac ggtgatagcg gacaaaacct
    16801 cagcctgctg aacgttggtt cattggtcag tttgatgatc tgtacggtaa tgaccattgt
    16861 ggcttctcgc aatcgtggct ggttgctgct acccattgtc tatgcctttg cgcttatcaa
    16921 cctggcgctg gcgaccttca tgcccaatga atacatcact catctggaag caacgcctgg
    16981 gatgctggtg cacattggct tatcgctctt ttcctatgcc acgctgatta tcgccgccct
    17041 gtacgcgctg caactggcgt ggattgatta ccaactgaag aacaagaagc tggcgtttaa
    17101 ccaggaaatg ccgccattaa tgagtatcga gcgtaaaatg ttccacatca cgcagattgg
    17161 cgtggtgctg ctaacgctca cgctttgcac tggcctgttc tacatgcaca acttatttag
    17221 catggaaaat atcgacaagg ccgtgctctc tatcgtggcg tggtttgtct atattgtgct
    17281 gctgtgggga cattatcatg aaggatggcg tggacgtcgc gtcgtctggt ttaacgttgc
    17341 gggtgcagtc attctgacac tggcctactt cggcagccga attgtccagc agttaatcag
    17401 ctaaacccag aaaaggagtt tcccctggaa cacatttcta ctactacgtt gatcattatt
    17461 ctgatcatca tggtggtcat ttcagcctat ttttccgggt ccgaaaccgg aatgatgacc
    17521 ctcaaccgct atcgtctgcg acatatggcg aaacagggta atcgctcggc caagcgcgtc
    17581 gaaaaattgc tgcgtaagcc agaccgcctg ataagcctgg tattaatcgg caataacctg
    17641 gtcaatattc ttgcctccgc gctcggcact attgttggga tgcgtttgta cggcgatgcg
    17701 ggcgtggcaa ttgcgactgg tgtgctgact tttgtcgtac tggtttttgc tgaggtattg
    17761 ccgaaaacca ttgccgcgct gtacccggaa aaagtcgctt atccgagtag ttttctgctg
    17821 gctccgctgc aaattttgat gatgccgctg gtctggttgc tgaatgctat cacccgtatg
    17881 ctgatgcgca tgatgggtat caaaaccgat atcgtggtta gcggctcttt gagcaaagaa
    17941 gagttgcgca ctatcgtgca tgagtcgcgc tcacaaattt cccgtcgcaa tcaggatatg
    18001 ctgctgtctg tgctcgatct ggaaaagatg accgttgatg acatcatggt gccgcgcagt
    18061 gaaattatcg gtattgatat caacgatgac tggaaatcga ttctgcgcca actatcccac
    18121 tcacctcacg ggcgcatcgt gctctaccgt gattcgctgg acgacgccat cagtatgctg
    18181 cgagtacgtg aagcctggcg gttgatgtcg gagaaaaaag agttcaccaa agaaaccatg
    18241 ctgcgcgccg cggacgagat ctattttgtc ccggaaggta cgcccctcag cacgcagttg
    18301 gtgaagtttc agcgcaacaa aaagaaagtc ggcctggtcg tcaacgaata tggagacatt
    18361 caggggctgg tgacggttga agatattctg gaagagatag ttggtgattt caccacgtcg
    18421 atgtcgccaa cacttgccga agaagtcact ccgcaaaacg acggttcggt gattattgat
    18481 ggcactgcca acgtgcggga aatcaacaaa gcctttaact ggcatctacc ggaagatgat
    18541 gcccgcacgg ttaatggcgt cattcttgag gcactggaag agatccctgt cgcaggcacc
    18601 cgcgtgcgta ttggcgagta cgatattgat attctcgacg tacaggacaa tatgattaag
    18661 caggtaaaag tttttcctgt gaaaccgctg cgcgagagtg tggcggagta acgaaaacgg
    18721 ccctgcattc gcatgcaggg ccgtgaatta ttacgaaaac agaaattacg cttttgcttt
    18781 cgctacagtt accatcgccg cacgaatcgt acgaccattc agcgtataac ccttctgcat
    18841 aatgcccagt acgttacctg gcgcaacgtc atcagattcc accattgcga tagcctgatg
    18901 cacattcggg tccagcggca cgttagtttc ggcgatcact tcgacaccaa acttacgcac
    18961 aacatccagc atcgacttca gcgtcagctc aatgccttca accatcgcag acatatccgg
    19021 gttagcttta tcagccactt ccagcgcacg atccaggcta tcaatcaccg gcagcaattc
    19081 gttgatgaat ttctccagcg cgaatttgtg ggctttttca atatccagtt cagtacgacg
    19141 acgcaggttt tccatttcgg cttttacacg caaaatgccg tcacgttcac gggtctgggc
    19201 ttcagccagc tgagcttcga gattcgcaat tttttcatcg cgcggatcca cctgctcagc
    19261 agaagcttct ggctcaactg cctcaatctc ttcgtgctga tccatgataa tttcttccgg
    19321 ggcttgcccc tcaggcgttt tctgttcttt actactcatg aatttctccg cgtttttttc
    19381 gcattcatct cgctaacttc gcttattatg gggatcagtt tcagggtttc aagggaagca
    19441 ctcacattgt catcaatctt cgcaacaagg acctcggaaa aatgaataat catttcaagt
    19501 gtattggcat tgtgggacac ccacggcacc ccactgcact gacaacacat gaaatgctct
    19561 accgctggct gtacacaaaa ggttacgagg tcatcgttga gcagcaaatc gctcacgaac
    19621 tgcaactgaa gaatgtgaaa actggcacgc tcgcggagat tgggcaactg gctgatctcg
    19681 cggtagtcgt tggtggcgac ggtaatatgc tgggcgcggc acgcacactc gcccgttacg
    19741 atattaaagt tattggaatc aaccgtggca acctgggttt cctgaccgac cttgatcccg
    19801 ataacgccca gcaacaatta gccgatgtgc tggaaggcca ctacatcagc gagaaacgtt
    19861 ttttgctgga agcgcaagtt tgtcagcaag attgccagaa acgcatcagc acggcgatta
    19921 acgaagtggt acttcatcct ggcaaagtgg cgcatatgat tgagttcgaa gtgtatatcg
    19981 acgagatctt tgcgttttct cagcgttctg atggcctgat tatttcgacg ccaacaggct
    20041 ccaccgccta ttccctctct gcgggcggtc ctattctgac accctctctg gatgcgatta
    20101 ccctggtgcc catgttcccg catacgttgt cagcgcgacc gctggtgata aacagcagca
    20161 gcacgatccg tctgcgtttt tcgcatcgcc gtaacgacct ggaaatcagt tgcgacagcc
    20221 agatagcact gccgattcag gaaggtgaag atgtcctgat tcgtcgctgt gattaccatc
    20281 tgaatctgat tcatccgaaa gattacagtt atttcaatac attaagcacc aagctcggct
    20341 ggtcaaaaaa attattctaa ttttacgcca gcctctttac tgtatataaa accagtttat
    20401 actgtacaca ataacagtaa tggtttttca tacaggaaaa caactatgtt ggcacaactg
    20461 accatcagca actttgctat cgttcgtgag cttgagattg attttcatag cggcatgacc
    20521 gtaataactg gcgagaccgg cgcgggtaaa tctattgcaa tagatgccct cggcctttgt
    20581 ctcggtggtc gcgctgaagc cgacatggtg cgtaccggcg ctgctcgtgc cgacctgtgc
    20641 gcccgttttt ctctgaaaga tacgccagcg gccctgcgct ggctggaaga aaaccagctt
    20701 gaagacggtc atgaatgttt gcttcgtcgc gtaatcagta gcgatggtcg ctcacgaggt
    20761 tttatcaacg gtacagctgt tcctctgtca caacttcgcg aactgggcca gttgttgatt
    20821 cagatccatg gtcagcacgc ccatcagtta ctcaccaaac ccgagcacca aaaattcctg
    20881 cttgatggct atgccaatga aacctctctg ctccaggaaa tgaccgcacg ttatcagttg
    20941 tggcatcaaa gctgccgtga cctcgcacat catcaacagt taagtcagga acgcgccgcc
    21001 cgtgcggaac tgctgcaata ccaattaaaa gaacttaacg aatttaatcc gcagcccgga
    21061 gagtttgagc aaatcgacga agagtacaaa cgtctggcga acagcggtca attgctgact
    21121 accagccaga atgcattggc agtaatggcc gacggtgaag acgcaaacct gcaaagtcag
    21181 ctttacacgg ctaaacaact ggtgagcgaa ttgattggca tggacagcaa actgtccggc
    21241 gtacttgata tgctggaaga agctaccatc cagattgctg aagccagcga tgaactgcgc
    21301 cactactgcg atcgtctgga tctcgatccc aaccgactgt ttgaacttga acagcgcatc
    21361 tcaaaacaga tttcgctggc acgtaaacat cacgtcagcc ctgaggcatt gccacagtat
    21421 taccagtcgc tactggaaga acagcagcaa ctggacgatc aggccgactc acaagaaacg
    21481 ctcgcgctgg cggtaacgaa acatcatcag caggcactgg aaaccgcgca cgcattacac
    21541 ctgcaacgcc agcattatgc aaatgagttg gcacagctga tcaccgacag tatgcatgcg
    21601 ctctcaatgc cgcatgggca gtttacgatc gatgttaaat ttgacgagca tcacctgggc
    21661 gctgacggtg ccgatcgtat tgagtttcgg gtaaccacca acccaggtca gccaatgcag
    21721 cctattgcca aagtcgcatc cggtggtgaa ttgtcacgca tcgcattggc aattcaggtc
    21781 atcacggcgc gtaaaatgga aaccccggca ctgatttttg atgaagtgga tgtagggatt
    21841 agcggtccaa cagcggcagt tgtcggcaaa ctgctgcgtc aacttggcga atcaactcag
    21901 gtgatgtgtg ttacccacct gccacaagtc gcgggatgtg gtcatcaaca ctattttgtc
    21961 agcaaagaaa ccgatggtgc gatgacagaa acacacatgc aatccctgga taaaaaagcg
    22021 cggttacaag agctggcgcg cctgcttggt ggcagtgaag tcacacgtaa cacactggcg
    22081 aatgcgaaag aactgcttgc ggcgtaaact tttttcctgc ttcacggtca gagtaaacag
    22141 caaaacgccg taggaccgga aagcaaaagg ttttaaagtg atgaaaggtc tattatcatc
    22201 ggcatattac agatgagcca cgtactgctc gggcccgaaa aggaatcaaa tcactatgcg
    22261 ctgtaaaacg ctgactgctg cagcagcagt actattgatg ttgaccgcag gctgttccac
    22321 tctggagcga gtggtttacc gtcctgacat caaccagggg aattatctga ccgctaacga
    22381 cgtatccaaa atacgcgttg gcatgacgca acaacaagtt gcgtacgcat tgggtacacc
    22441 gttgatgtcc gatccatttg gtacgaatac ctggttctat gtcttccgcc agcaaccagg
    22501 tcatgaaggt gtaacgcagc aaacgctgac gctgaccttt aacagtagcg gtgtgttgac
    22561 caacattgat aacaaacctg cgctgagtgg taactaataa taaagttgct ctcaaagacg
    22621 ttaaaaaagg tgctcaatga gcaccttttt tctgtctgtt atttattcgc tgatttttct
    22681 gctcgttgcc tgcgcagctc tttcggatcg gcaatgagag ggcgataaat ctccacccga
    22741 tcgccatcat gcacactatc gctcagtttt gccggacggc tataaatgcc gactttgttt
    22801 ttagttaaat cgatatcggt acgcaattcc agcaagccac tggcgcgaat agcttcttca
    22861 accgtcgctc cctcctgcag cgtcacgcgc tgcaggtact gcttctcagg tagcgcataa
    22921 gccacctcaa cggcaatttt acctggcact gtaaacctct ttcgcacgaa ccgtaaaagc
    22981 ctggaccata ttagccgcca gctctttaaa cacgcgacca aaggcgagtt caatcaactt
    23041 attggtaaac tcaaaatcga gatgaaactc gatacgacac gcctcctggc tcagcggcgt
    23101 aaacttccat ccaccgatca atttcttgaa cggcccatcc accagattca taagaatact
    23161 ttggttactg gtcaactggt tgcgggtagt aaacgttttg ctgatcccag ccttagagac
    23221 atctaccgcc gcagtcatct gcccaggagt ggactccaga atccgacttc cggtacaacc
    23281 cggcaaaaac tgaggataag actgaacgtc attcactaac tgatacattt gctccgcgct
    23341 gtagggtacc agtgcggtcc ggctaatctg aggcataaca atttccatca acaaaaatcc
    23401 aacaaataat atcatttatc ctgctgtaaa aaaaacgcta tcccggcgct gggtaacatc
    23461 gggttcatgc taagatagag ccttgtcccc cgcaggattg atatggggtg ttttcgattt
    23521 cagattaccg atgattcacg acgcttatga cgaagaaaaa agcacataaa cctggttcag
    23581 cgaccatcgc gcttaacaag cgcgcccggc acgaatactt tatcgaagaa gagttcgagg
    23641 cgggacttgc cctgcaaggc tgggaggtta aatccctgcg cgcaggaaaa gccaatatca
    23701 gcgacagcta cgtccttctg cgtgacggag aggcatttct gtttggcgct aacatcacgc
    23761 caatggctgt ggcctccacg catgtggtgt gcgatcctac ccgtacccgc aagttacttc
    23821 tcaaccagcg cgaactggac tcattgtacg gtcgcgtcaa tcgagaaggc tataccgtag
    23881 tggcgctcgc cctgtactgg aaaaatgcct ggtgcaaagt gaaaatcggc gtcgccaaag
    23941 gtaagaaaca gcacgataaa cgttcagata tcaaagagcg cgaatggcag gtggataaag
    24001 cgcgtatcat gaaaaacgcc caccgttaaa cctgcactcc aattattgac cagttcctca
    24061 ccgcgcctcc ctctccggcg gcgcgaatga acatcttatt ggctatcaca tccgacacaa
    24121 atgttgccat cccattgctt aatcgaataa aaatcaggct acatgggtgc taaatcttta
    24181 acgataacgc cattgaggct ggtcatggca ctcatgaatc tggtatactt accgttacac
    24241 attggggctg attctggatt cgacgggatt tgcgaaaccc aaggtgcatg ccgaggggcg
    24301 gttggcctcg taaaaagccg caaaaaatag tcgcaaacga cgaaaactac gctttagcag
    24361 cttaataacc tgcttagagc cctctctccc tagcctccgc tcttaggacg gggatcaaga
    24421 gaggtcaaac ccaaaagaga tcgcgtggaa gccctgcctg gggttgaagc gttaaaactt
    24481 aatcaggcta gtttgttagt ggcgtgtccg tccgcagctg gcaagcgaat gtaaagactg
    24541 actaagcatg tagtaccgag gacgtaggaa tttcggacgc gggttcaact cccgccagct
    24601 ccaccaatca tgattggacg gtgcaaggac aacaccaaca aaaacaggaa gttagaagtc
    24661 tcagcaagac accgaccaga cggtgaggag acataaaagg atacgcaaag gagccgcggc
    24721 tcttggtgat atgaaagccc acagatgtgg gctttttcgt tgatggtcag aacgaccagt
    24781 tcgcaccagc caccgcgttc cacggggatt ccacaccggc accatggcta taccccaccc
    24841 cgagatgtcc gcttaacgta ctgctgaatg aggctttaat acctgcctgg tatattccac
    24901 gtctgcccga caaatcattg acgaaattac cgtcattatt caccttcacc cggttatcat
    24961 cgacaaattc tttgcgcaca gccgccttca gccacggctc aatttccata ccgttcccca
    25021 gacgcatgtt gtaactcagc gttgcgccca gttcacgata tatactgcgg gtatcgactg
    25081 atttcgattc catgccattg gataaatgat attcggggtt atcagcggtg aaccccgtta
    25141 acgatgcata cggcgtcagg ttccagttac catccgtaaa tcgcatcccg gtttcaatgt
    25201 gaccgcccag cccgttgctg cgataactgc cgttggcggc tccaccgctg ctcattttac
    25261 cggctacgtt actttcaaag cggttcagct tcacgatacc gtccagatag aaaccacttt
    25321 catgttccca gctggcatag ccccccagag aataactggc cacactgcca tgtcctccac
    25381 gatcaaaacc aatatgtgaa tgggaataac ccataaaagc gcccagcgtc gcaatcccct
    25441 caggaatatc attacggcta tcgatcccca ccgtcattcc ggtcagcgtc tgctcaaacc
    25501 cggcacccgc atcggtggtg acattattac gggtgttata cgtcgtcccc cagacattat
    25561 tgttgtgtgg actcgctttc attatgttca accgctcgcg aatactgttt agctcagcat
    25621 caaagaccaa cggtaatgtt gctgccatat tgagtacggc tgctgtagaa ggcgtgatgc
    25681 gtttctccgg gacgggtgtc ggcgttggag cgggagtcgg gtctggtttc ggatccggtt
    25741 ttgggtctgg ttttggatcc ggtttcggat ttgggttggg gtccgggttg ggtttgacat
    25801 cattggtcag gttccagttg ctgttgccgt cgcttttcag gacatactca taggtcccaa
    25861 gatcaacgaa accgccggta ttacccagcg taaacgaagc atcccctccc cctgttttca
    25921 ccagcgtcat cgcgtcgtca gactgagggc tgacgccggt atcctgaaca aagattttaa
    25981 aattgccagt ggcgttgttg ttgacgacca gttgatcgcc ccgggagcct gcaacgttgg
    26041 tatgcaggta gaaattaccg ctgccggaaa gttcactggt ggtcagcgta ttgtagatac
    26101 cgttagttgt ggcaggcgct gctgtttgtg ctgataaata aacatcaccg tcgttgagga
    26161 gtaaactgtt tactctatat tcgcagttgc tggtgcctgc acaggaatta ttgctgttaa
    26221 gctagacact gccccgactg gcagccgtca ggtcggcaag cgtcgtatcg acgccatttc
    26281 cgatagttaa tgtcgcgcta tcggtaatcc ggaccacccc ttcaagttta actggcgtaa
    26341 cattatcccg tggcgtcatt aacgacaggc ttcctgtcgc gccactgacc gatgcatccg
    26401 ccagcgtacc tgcgtagacg attgccgtcc cgccagcgat cagtagatct tctgcccggg
    26461 ccagagcctg aaactcatct tttgaccgac caagggtata ttgcccaccg gaattaacct
    26521 ttgtggcgaa gtcctgaccc aggttttgca ttgccccacc gttgccaacc gtggaatcgc
    26581 gagcttcggt acctgctaat accaataaat taccgccatt ttccagcagc acattggtcg
    26641 ctaaatttcc ggcaatggaa aaggtgccgt actggtgagt accgctgatt tcaataccgt
    26701 tagccgtgct cgtctggaga gcggcaccgc tgttctggat gatatctgtc gctttgccat
    26761 tatcgttgac tgtcagcgta ccgccttcat taatcgttgt ttttactgcc tcaccgttag
    26821 ccgaaactgt ttgtattccg ccgtcgttaa tcgttgtctc attcgccacc ccctcgacga
    26881 tttgttcgcc gccggtgagc gtcgtgcctg tcgcagtggc ttttgttttg acgatctccc
    26941 gcccgcccgc attgacctgt gttttggcgg aagtggtgtc tgactccacg gttaacacgc
    27001 cgccatctgc cagcaggata ttgttcgccg catcctgctc aatgctgaac gcgacgccat
    27061 cagcgcgtgt ccctgtgacc cgcgtcgctc tggtggttgc aaccaacgcg ccctggctac
    27121 tttgctgtat ccccgttgcg ctgcctttct cccgcacatc gagagtgccg ccttcattaa
    27181 gcaccgagtt ttcagccaga ccgccctcat taactacctg tgaaccgcca ttaataatgg
    27241 aaccttccgc tgtcccgttt accataattt gttgtaggcc agagacgata tcggtattga
    27301 tcgccttacc ataattctga acggtttgcg taccgccatt gatgtgcgtt ttgtctgttg
    27361 acccaccatc aacaatttgt tcaccacttt cgatatttgc ctcagtggct aaaccatata
    27421 ccgtttgctt gccacctttg atatttgctt tttcagaagt ggcactgaca tatattgttt
    27481 gggtaccagc actattaagt acagtaccaa catcttttcc ataaacatcc attttgccgt
    27541 tggcattaat aatcgtgtca actgcccggg aaccagtgac gactgttaat gagccagcgt
    27601 tttccagcac tacattttta gcttctgaat tcctgatgta gaaagcatca ccataactgt
    27661 tggttccttc gataagtgtt ccggaggtcg tggaagcaat taatgcgccg ccggattgtt
    27721 gctcaacatg cttagcctca ccaccgtcct gaacctccag aacgccacca ttattaagtc
    27781 tggtgctatc tgttttagcc tccttctgga caatcagctt accgccagca tcaatggtag
    27841 tatttttcgc cgaggtttta gccattaccg tcagttcgcc ggtattttcc agcacaacat
    27901 aattagcctc tcctccggta atagtgaagt gagagagctt gttgtatcct tcgatatcag
    27961 tccctgcgcc cgtgttggca actaaagcac tgcccgtctc ctggttaacc ccatgtgcaa
    28021 taccgccggt atagacaatc agcgagcctc cggcgctaat attgctgcca gttgccgtac
    28081 catctttctc aacaacctgc cggctcccag aggatatatt tgtcgtgtca gctttcccgc
    28141 cgctcttgat attttgcgtt ccactgttga tattggtgcc cgtggcaata ccatgattat
    28201 taatattctg tgtgccacca ttaattatgg tatttgtcgc gtttccggca acatccataa
    28261 cgccgccatt atctattcgg gtcgcatcag ctttagcatt cgttaaaact gacattgttc
    28321 ctttatcttt aataatcgtc ttatttgccg aaccatatgc gtttatgtct aaatgaccac
    28381 cgttttccag caacacattc tctgccacgt tattgtggat ggagaatgcc ccttcactat
    28441 tcgtaccgct caccgtcaaa tcgtaagtcg ttacttttaa agcggctcca tcgtgctgag
    28501 taatattagt tgccgtacca cctctaacat caagcacgcc gccggaataa acttcaataa
    28561 catccgagga gctcgtgtta tcaacaattt gcgtaccacc agaatagatc tgcgtatttt
    28621 ttgccgttga cttactattc agagactgag ttccgccttc aatcgtcgtg tccagcgcac
    28681 ggctctcata tactctttgc tcaccgccat ttttaatggc ggttgtttct actgtgctct
    28741 gttcaacata ctgtcgccca ccatttatgg ttgtgttcgt cgccagactt ccttgcgtga
    28801 tgtcctgata accagactta tttatcgtcg taccgtcaac atgcccctga gttgatactg
    28861 actggcctcc accatcaatg attgttccat ttgcagtccc cccctctatg cgtgaagtac
    28921 cgcccttaat tgtcgtgtca ttgctggtac cacctttata aacatattga ttgccacttt
    28981 cgattatcgt gccagtagaa attcctccgt actcaattga ctgtctgcct ccattaatgg
    29041 ttgtattatt agcttgcccg ttaatatcgg catggattga tactagttgc tcgccaccag
    29101 tttcaataat actactatta gatatcccac catagacctc ctgccggcca tggttgataa
    29161 tatgagtgtt atttgttgta cctcgttcat ctactcgttg gttgccatct acagtctcat
    29221 cgtttaccac accaataaca ttagtagtga aggccgccat cccgggctgg gcatatatta
    29281 aggcagatat caataaggaa agtactgagc ggcgaaaata atagggactg gtcctgttca
    29341 taaatttcat cctctgaaaa gtgaatactg agtagcgttt aagcgacctt agctttgctg
    29401 caacatcagc ccacaggcac cagaccaggg gattcatcct gaagagacag cgcaagtgta
    29461 ttgtgttcac cgctcatcaa agacatcatg atgaaatgat gatattccgc ataagaatga
    29521 ggcatttttt taagacattg tgctgaagga tgattggata aaaaagtcaa tcttttcagg
    29581 aaatacggcg tattcttttc tttcgacatt gaagccgtcg gaaaaataaa atgatttaca
    29641 taatcgtttc tgatgaatat cttctgctca cataaaaatc acacaataac tttgagatcg
    29701 cagattgttt tacttttaca gcattcgtcc ccccattgtt ggggaaatat agattgggcc
    29761 agagcacgaa agttaatacc acgtttgcac agctcctcca acagcacgac aagatgccac
    29821 atactgcgcc ccagtcggtt cagtttacag actagcagtg cgtaccctgc cgataatgtc
    29881 ctgagcagtt tttcagtccg ggtctgctgc cacggttatg cgctgaagtg gtaactctga
    29941 gcacgcagtt catcagtcag gcgtggtaca ccgtaacgct gttattgctg ggtaatatca
    30001 aaaaaacttt caggcagcta aggaaagttg aaccagacat tagatgaaat atttcaacca
    30061 attacagcac caattcagtc actgctagcc caccaaataa atcaaggggt tacatgaaaa
    30121 cgtagcccct ttttctttgg tagtgacact aaaatggatg tagtgtgaag aataacccca
    30181 tttacttaat caataataca tattgtttca atctacgtta ttatctcttc gtaaaaatag
    30241 ccatttattt atcattgaaa actactttta gaacttcata caaggggact attcacaaca
    30301 ggactattct caacgggacc atcatcaggg gagttatcat caaagtcatc atccataaat
    30361 aaaatatcat cgaatggtgc cacacccgtg attagtttta tttttttatt acgatcagac
    30421 aagactccac ttaaaccgtt ttcgctgacg cgttctaatg atttttcatt actcttgttg
    30481 taagcaggcg cattaaaaat acatggagta tcaagatcaa acaatgacgt tccccagttc
    30541 acatattgaa tatcatagtt actgaagttc tgtccagaaa agaagcatcc cttaaaatcc
    30601 aatccacgta aattatataa accaccctct tcttttggga gagtaatttt aattctggct
    30661 atctcccaga caaaattacc atttttgtat ttgaataccg tttcaagctc tcctccagac
    30721 agcttgactt ctggaaataa tttgaaatta aaccctacat tattatgtgt caacgtagat
    30781 gaacaaaaga tggaaaaagc ttgcagtgct gaattatagc tatcgatttt atcttgaggc
    30841 tgcgctcttg gtaaaaactt atagcaacac tcataaaaat taagtagaaa ctctgatgac
    30901 cttccatttt tatcaaataa tacccgctga aaatgctgca caaacttatt cgttttttct
    30961 tgaatatcta tggtgtgttc ctttgactct aacaaagatg aatcctgttg aagtgcattg
    31021 ctcatctggt tgaggaacaa ctgcatttct ttcaacttat ctccatagtg acctttaact
    31081 tgctgagaat ttttagttac agttgaaacc gtatctgtgt ggttttcata taaattatgt
    31141 gattccatac agtcatttgg cggcgtttct gaaataacac tacgcgttct acctggctga
    31201 agtgaagcaa catgaaaatc actttttctt atattgccga atagggtctg ttcatttctc
    31261 ttagcgcatt caataaactg atcaacatta tttttattag atgacaggtt aatttcagaa
    31321 accgcatttt ctttgttctc cagctttagt ttaacgagaa ggtcttccca caccgttttt
    31381 tttaaaaata ctacgtcagg ctcaccatca gcaactaact cttgattatt atcaaagtgt
    31441 acgttgtata cttttaattt attttcatta gcatcatatt taatacgttt taattgttct
    31501 ccggctccca taatgacaaa agcattgcct tcatgatatt tacattcaga catcattttt
    31561 tgtaaaattt caagagcacc gttatacgtc cctgaggcag cttctttaca aattaatttt
    31621 ataatactat aagctagtaa ctccatggat ttagaagatt ttctttcatt acaacttcca
    31681 ctatttataa atgtgctagt gttaatttcg ttgcttttac taactaacat tgtctattcc
    31741 tcagttaatg tctacatgg
//
LOCUS       DACAOP010000048        31753 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.048, whole genome shotgun sequence.
ACCESSION   DACAOP010000048 DACAOP010000000
VERSION     DACAOP010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31753
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.048"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..584
                     /gene="yghU"
                     /locus_tag="IT892_002484"
     CDS             <1..584
                     /gene="yghU"
                     /locus_tag="IT892_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HAP3135690.1"
                     /translation="NPNSKIPALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAK
                     RTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQH
                     KFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRG
                     RIVNRTNGPLNEQLHERHDASDFETNTEDKRQG"
     gene            complement(707..955)
                     /gene="hybG"
                     /locus_tag="IT892_002485"
     CDS             complement(707..955)
                     /gene="hybG"
                     /locus_tag="IT892_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation factor HybG"
                     /protein_id="HAP3135691.1"
                     /translation="MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADL
                     LGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA"
     gene            complement(968..1309)
                     /gene="hypA"
                     /locus_tag="IT892_002486"
     CDS             complement(968..1309)
                     /gene="hypA"
                     /locus_tag="IT892_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HAP3135692.1"
                     /translation="MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAV
                     RFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPLCHGERLRVDTG
                     DSLIVKSIEVE"
     gene            complement(1302..1790)
                     /gene="hybE"
                     /locus_tag="IT892_002487"
     CDS             complement(1302..1790)
                     /gene="hybE"
                     /locus_tag="IT892_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-2 assembly chaperone"
                     /protein_id="HAP3135693.1"
                     /translation="MTEEIAGFQTSPKAQVQAAFEEIARRSMHDLSFLHPSMPVYVSD
                     FTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVSEKIGLQLPYGTMTFTVGELDGV
                     SQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVTNPDVPHAGRRALLFGRRSGE
                     NA"
     gene            complement(1783..2277)
                     /locus_tag="IT892_002488"
     CDS             complement(1783..2277)
                     /locus_tag="IT892_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HAP3135694.1"
                     /translation="MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTA
                     GMELLGDMANRDHLIIADAIVSKKNAPGTMMILRDEEVPALFTNKISPHQLGLADVLS
                     ALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPRE
                     AIHD"
     gene            complement(2277..3980)
                     /gene="hybC"
                     /locus_tag="IT892_002489"
     CDS             complement(2277..3980)
                     /gene="hybC"
                     /locus_tag="IT892_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 large subunit"
                     /protein_id="HAP3135695.1"
                     /translation="MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEI
                     VKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESALNIDVPVNAQYIRNIILAAHTTH
                     DHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVA
                     SGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNL
                     AVGGVANPINLDGLGVLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRG
                     KGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSDEYLIKGIQESAKHS
                     WYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRE
                     STQNKLNEIVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNI
                     GKGDHTTFVKPNIPATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGP
                     RNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKV
                     L"
     gene            complement(3977..5155)
                     /gene="hybB"
                     /locus_tag="IT892_002490"
     CDS             complement(3977..5155)
                     /gene="hybB"
                     /locus_tag="IT892_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase cytochrome b subunit"
                     /protein_id="HAP3135696.1"
                     /translation="MSHDPQPLGGKIISKPVMIFGPLIVICMLLIVKRLVFGLGSVSD
                     LNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFNRGQYHPLVRPALLASLFGYSLG
                     GLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
                     VSLQRLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSLLTAF
                     IMGFSIVIFEGSLVQAGLRGNGPDEKSLFVKLTNTISVLLAIFIVLRFGELIYRDKLS
                     LAFAGDFYSVMFWIEVLLMLFPLVVLRVAKLRNDSRMLFLSALSALLGCATWRLTYSL
                     VAFNPGGGYAYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
                     "
     gene            complement(5145..6131)
                     /gene="hybA"
                     /locus_tag="IT892_002491"
     CDS             complement(5145..6131)
                     /gene="hybA"
                     /locus_tag="IT892_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 operon protein HybA"
                     /protein_id="HAP3135697.1"
                     /translation="MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDS
                     TLCVGCQACVTKCQDINFPERNPQGEQTWSNNDKLSPYTNNIIQVWTSGTGVNKDQEE
                     NGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
                     KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRL
                     ALKPGSEYHYPRQTLKSGDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPK
                     LDDLSTGARSENIQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHHDGGDDHES"
     gene            complement(6134..7252)
                     /gene="hybO"
                     /locus_tag="IT892_002492"
     CDS             complement(6134..7252)
                     /gene="hybO"
                     /locus_tag="IT892_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 small subunit"
                     /protein_id="HAP3135698.1"
                     /translation="MTGDNTLIHSHGINRRDFMKLCAALATTMGLSSKAAAEMAESVT
                     NPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENK
                     HNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAW
                     GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKN
                     RPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQ
                     FCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQKPDVNAKEGGNVSA
                     GAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE"
     gene            complement(7441..7728)
                     /locus_tag="IT892_002493"
     CDS             complement(7441..7728)
                     /locus_tag="IT892_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2623 domain-containing protein"
                     /protein_id="HAP3135699.1"
                     /translation="MNNHFGKGLMAGLKATHADSAVNVTKFCADYKRGFVLGYSHRMY
                     EKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSCSTLRFFMAGYRLEN"
     gene            complement(7847..8610)
                     /locus_tag="IT892_002494"
                     /pseudo
     CDS             complement(7847..8610)
                     /locus_tag="IT892_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405915.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
     gene            complement(8588..8731)
                     /locus_tag="IT892_002495"
     CDS             complement(8588..8731)
                     /locus_tag="IT892_002495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135700.1"
                     /translation="MPRLTAKDFPQELLDYYDYYAHGKISKREFLNLAAKCSRRDDGI
                     SVV"
     gene            8888..9928
                     /gene="gpr"
                     /locus_tag="IT892_002496"
     CDS             8888..9928
                     /gene="gpr"
                     /locus_tag="IT892_002496"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAP3135701.1"
                     /translation="MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALES
                     QRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDM
                     WPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
                     KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVG
                     CIAFTPLAQGLLTGKYLNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQ
                     RGQSMAQMALSWLLKDDRVTSVLIGASRAEQLEENVQALNNLTFSTKELAQIDQHIAD
                     GELNLWQASSDK"
     gene            complement(9968..10462)
                     /locus_tag="IT892_002497"
     CDS             complement(9968..10462)
                     /locus_tag="IT892_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HAP3135702.1"
                     /translation="MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPN
                     IFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDA
                     TSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
                     RHNH"
     gene            10653..11537
                     /gene="yghA"
                     /locus_tag="IT892_002498"
     CDS             10653..11537
                     /gene="yghA"
                     /locus_tag="IT892_002498"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HAP3135703.1"
                     /translation="MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGS
                     GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKA
                     VLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
                     VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA
                     EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQE
                     SSYVTAEVHGVCGGEHLG"
     gene            complement(11809..12234)
                     /gene="exbD"
                     /locus_tag="IT892_002499"
     CDS             complement(11809..12234)
                     /gene="exbD"
                     /locus_tag="IT892_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein ExbD"
                     /protein_id="HAP3135704.1"
                     /translation="MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVD
                     VKVNLPASTSTPQPRPEKPVYLSVKADNSMFIGNDPVTDETMITALNALTEGKKDTTI
                     FFRADKTVDYETLMKVMDTLHQAGYLKIGLVGEETAKAK"
     gene            complement(12241..12975)
                     /locus_tag="IT892_002500"
     CDS             complement(12241..12975)
                     /locus_tag="IT892_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biopolymer transporter ExbB"
                     /protein_id="HAP3135705.1"
                     /translation="MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSK
                     SVEFFNQKRRLKREQQLLAEARSLNQANDIAADFGSKSLSLHLLNEAQNELELSEGSD
                     DNEGIKERTSFRLERRVAAVGRQMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
                     QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNVFARQIGGFKAMLGDVAAQVLL
                     LQSRDLDLEASAAAHPVRVAQKLRAG"
     gene            13227..14414
                     /gene="metC"
                     /locus_tag="IT892_002501"
     CDS             13227..14414
                     /gene="metC"
                     /locus_tag="IT892_002501"
                     /EC_number="4.4.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HAP3135706.1"
                     /translation="MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKH
                     ATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGD
                     HVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSIT
                     MEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDA
                     MIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEW
                     LAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLF
                     SMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFA
                     RIV"
     gene            14554..15213
                     /locus_tag="IT892_002502"
     CDS             14554..15213
                     /locus_tag="IT892_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HAP3135707.1"
                     /translation="MAVIQDIIAALWQHDFAALADPHIVSVVYFVMFATLFLENGLLP
                     ASFLPGDSLLILAGALIAQGVMDFLPTIAILTAAASLGCWLSYIQGRWLGNTKTVKGW
                     LAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLPNRRFQFFNWLS
                     GLLWVSVVTSFGYALSMIPFVKRHEDQVMTFLMILPIALLTAGLLGTLFVVIKKKYCN
                     A"
     gene            complement(15253..16152)
                     /locus_tag="IT892_002503"
     CDS             complement(15253..16152)
                     /locus_tag="IT892_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003024513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP3135708.1"
                     /translation="MKREEICRLLADKVNKLKNKENSLSELLPDVRLLYGETPFARTP
                     VMYEPGIIILFSGHKIGYINERVFRYDANEYLLLTVPLPFECETYATSEVPLAGLRLN
                     VDILQLQELLMDIGEDEHFQPSMAASGINSATLSEEILCAAERLLDVMERPLDARILG
                     KQIIREILYYVLTGPCGGALLALVSRQTHFSLISRVLKRIENKYTENLSVEQLAAEAN
                     MSVSAFHHNFKSVTSTSPLQYLKNYRLHKARMMIIHDGMKASAAAMRVGYESASQFSR
                     EFKRYFGVTPGEDAARMRAMQGN"
     gene            16346..17509
                     /gene="yqhD"
                     /locus_tag="IT892_002504"
     CDS             16346..17509
                     /gene="yqhD"
                     /locus_tag="IT892_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HAP3135709.1"
                     /translation="MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKT
                     GVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTK
                     FIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDK
                     QAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAE
                     GILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAM
                     HGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFF
                     EQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR"
     gene            17614..18441
                     /gene="dkgA"
                     /locus_tag="IT892_002505"
     CDS             17614..18441
                     /gene="dkgA"
                     /locus_tag="IT892_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgA"
                     /protein_id="HAP3135710.1"
                     /translation="MANPTVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRS
                     IDTAAAYKNEEGVGKALKNASVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYID
                     LYLMHWPVPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQ
                     IELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVI
                     RWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKRLGPDPDQFGG"
     gene            18641..19567
                     /locus_tag="IT892_002506"
     CDS             18641..19567
                     /locus_tag="IT892_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjP/YqhG family protein"
                     /protein_id="HAP3135711.1"
                     /translation="MKIILLFLAALASFTVHAQPPSQTVEQTVRHIYQNYKSDATASY
                     FGETGERAITSARIQQALTLNDNLTLPGNIGWLDYDPVCDCQDFGDLVLESVAITQTD
                     ADHADAVVRFRIFKDDKEKTTQTLKMVAENGRWVIDDIVSNHGSVLQAVNSENEKTLA
                     ALASLQKEQPEAFVAELFEHIADYSWPWTWVVSDSYRQAVNAFYKTTFKTANNPDEDM
                     QIERQFIYDNPICFGEESLFSRVDEIRVLEKTADSARIHVRFTLTNGNNEEQELVLQR
                     REGKWEIADFIRPNSGSLLKQIEAKTAARLKQ"
     gene            19618..19875
                     /gene="yqhH"
                     /locus_tag="IT892_002507"
     CDS             19618..19875
                     /gene="yqhH"
                     /locus_tag="IT892_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YqhH"
                     /protein_id="HAP3135712.1"
                     /translation="MKTIFTVGAVVLATCLLSGCVNEQKVNQLASNVQTLNAKIARLE
                     QDMKALRPQIYAAKSEANRANTRLDAQDYFDCLRCLRMYAE"
     gene            complement(19918..22137)
                     /locus_tag="IT892_002508"
     CDS             complement(19918..22137)
                     /locus_tag="IT892_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HAP3135713.1"
                     /translation="MSSISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDS
                     CDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWSSKDDFMRLGKPNLFFG
                     VTAGNMDSMINRYTADRRLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
                     GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGEPISEIR
                     DVRNTAIIVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKA
                     VTVQPPRPKPWEKTYVLLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRY
                     VWINPPAIPLSTEEMDSVFALPYKRVPHPAYGNARIPAYEMIRFSVNIMRGCFGGCSF
                     CSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAE
                     QTCRRLSCVYPDICPHMDTNHEPTINLYRRARDLKGIKKILIASGVRYDIAVEDPRYI
                     KELATHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDTYSKQAGKEQYLIPY
                     FISAHPGTRDEDMVNLALWLKKHRFRLDQVQNFYPSPLANSTTMYYTGKNPLAKIGYK
                     SEDVFVPKGDKQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGSRRDCLVPAPTIE
                     EMREARRQNRNTRPALTKHTPMATQRQTPATAKKASSTQSRPVNAGAKKRPKAAVGR"
     gene            complement(22248..23660)
                     /gene="ftsP"
                     /locus_tag="IT892_002509"
     CDS             complement(22248..23660)
                     /gene="ftsP"
                     /locus_tag="IT892_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsP"
                     /protein_id="HAP3135714.1"
                     /translation="MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRR
                     GQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIRVWKGDDVKLIYSNRLTENVSMT
                     VAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGM
                     WLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQ
                     SPYVEVSRGWVRLRLLNASNSRRYQLQMNDGRPLHVISGDQGFLPAPVSVKQLSLAPG
                     ERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTD
                     SLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADE
                     PQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNS
                     QTLEMADRGSIGQLLVNPVP"
     gene            complement(23735..24472)
                     /gene="plsC"
                     /locus_tag="IT892_002510"
                     /gene_synonym="parF"
     CDS             complement(23735..24472)
                     /gene="plsC"
                     /locus_tag="IT892_002510"
                     /gene_synonym="parF"
                     /EC_number="2.3.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acylglycerol-3-phosphate O-acyltransferase"
                     /protein_id="HAP3135715.1"
                     /translation="MLYIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGR
                     LAPLFGLKVECRKPTDAESYGNAIYIANHQNNYDMVTASNIVQPPTVTVGKKSLLWIP
                     FFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
                     TGAFHAAIAAGVPIIPVCVSTTSNKINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELA
                     AHCRSIMEQKIAELDKEVAEREAAGKV"
     gene            complement(24706..26964)
                     /gene="parC"
                     /locus_tag="IT892_002511"
     CDS             complement(24706..26964)
                     /gene="parC"
                     /locus_tag="IT892_002511"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001639862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAP3135716.1"
                     /translation="MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRR
                     IVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDIACYEAMVLMAQPFSYRYPLVDG
                     QGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR
                     LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTE
                     AEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRN
                     KKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL
                     DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEI
                     IRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGI
                     LASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMG
                     WVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ
                     GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITL
                     PENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARG
                     EDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEID
                     SPRRASSGDSEE"
     gene            complement(27102..28709)
                     /locus_tag="IT892_002512"
     CDS             complement(27102..28709)
                     /locus_tag="IT892_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP3135717.1"
                     /translation="MYTRNLLWLVSLVSAAPLYAADVPANTPLAPQQVFRYNNHSDPG
                     TLDPQKVEENTAAQIVLDLFEGLVWMDGEGQVQPAQAERWEILDGGKRYIFHLRSGLQ
                     WSDGQPLTAEDFVLGWQRAVDPKTASPFAGYLAQAHINNAAAIVAGKADVTSLGVKAT
                     DDRTLEVTLEQPVPWFTTMLAWPTLFPVPHHVIAKHGDSWSKPENMVYNGAFVLDQWV
                     VNEKITARKNPKYRDAQHTVLQQVEYLALDNSVTGYNRYRAGEVDLTWVPAQQIPAIE
                     KSLPGELRIIPRLNSEYYNFNLEKPPFNDVRVRRALYLTVDRQLIAQKVLGLRTPATT
                     LTPPEVKGFSATTFDELQKPMSERVAMAKALLKQAGYDASHPLRFELFYNKYDLHEKT
                     AIALSSEWKKWLGAQVTLRTMEWKTYLDARRAGDFMLSRQSWDATYNDASSFLNTLKS
                     DSEENVGHWKNAQYDALLNQATQITDATKRNALYQQAEVIINQQAPLIPIYYQPLIKL
                     LKPYVGGFPLHNPQDYVYSKELYIKAH"
     gene            complement(28842..29237)
                     /gene="mqsA"
                     /locus_tag="IT892_002513"
     CDS             complement(28842..29237)
                     /gene="mqsA"
                     /locus_tag="IT892_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin MqsA"
                     /protein_id="HAP3135718.1"
                     /translation="MKCPVCHQGEMVSGIKDIPYTFRGRKTVLKGIHGLYCVHCEESI
                     MNKEESDAFMAQVKAFRASVNAETVAPEFIVKVRKKLSLTQKEASEIFGGGVNAFSRY
                     EKGNAQPHPSTIKLLRVLDKHPELLNEIR"
     gene            complement(29239..29535)
                     /gene="mqsR"
                     /locus_tag="IT892_002514"
     CDS             complement(29239..29535)
                     /gene="mqsR"
                     /locus_tag="IT892_002514"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin MqsR"
                     /protein_id="HAP3135719.1"
                     /translation="MEKRTPHTRLSQVKKLVNAGQVRTTRSALLNADELGLDFDGMCN
                     VIIGLSESDFYKSMTTYSDHTIWQDVYRPRLVTGQVYLKITVIHDVLIVSFKEK"
     gene            complement(29740..30222)
                     /locus_tag="IT892_002515"
     CDS             complement(29740..30222)
                     /locus_tag="IT892_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP3135720.1"
                     /translation="MTNLTLDVNIIDFPSIPVAMLPHRCSPELLNYSVAKFIMWRKET
                     GLSPVNQSQTFGVAWDDPATTAPEAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVA
                     RHVGELDDISHTVWGIIRHWLPASGEKMRKAPILFHYTNLAEGVTEQRLETDVYVPLA
                     "
     gene            complement(30275..30667)
                     /gene="ygiW"
                     /locus_tag="IT892_002516"
     CDS             complement(30275..30667)
                     /gene="ygiW"
                     /locus_tag="IT892_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB fold stress tolerance protein YgiW"
                     /protein_id="HAP3135721.1"
                     /translation="MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNG
                     SVTTVESAKSLRDDTWVTLRGNIVERISDDLYVFKDASGTINVDIDHKRWNGVTVTPK
                     DTVEIQGEVDKDWNSVEIDVKQIRKVNP"
     gene            30819..31478
                     /gene="qseB"
                     /locus_tag="IT892_002517"
     CDS             30819..31478
                     /gene="qseB"
                     /locus_tag="IT892_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator QseB"
                     /protein_id="HAP3135722.1"
                     /translation="MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAP
                     YDAVILDLTLPGMDGRDILREWREKGQREPVLILTARDALAERVEGLRLGADDYLCKP
                     FALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
                     LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGE
                     K"
     gene            31475..>31753
                     /locus_tag="IT892_002518"
     CDS             31475..>31753
                     /locus_tag="IT892_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     QseC"
                     /protein_id="HAP3135723.1"
                     /translation="MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELF
                     DTQLMLFAKRLSTLDLNEINAADRMAQTPNRLKHGHVDDDALTFAIFTH"
BASE COUNT         7797 a         8448 c         7994 g         7514 t
ORIGIN      
        1 tgaacccaaa ctcgaagatc ccggcgctgc gcgatcatac gcataatccg ccgatccgcg
       61 tgtttgaatc tggttcgatc ctgctttatc tggcggagaa atttggctac ttcctgccgc
      121 aggatttggc aaagcgtact gaaacgatga actggctgtt ctggttacag ggcgcggcac
      181 cgttcctcgg cggtggtttt ggtcactttt accattacgc accggtaaag attgagtacg
      241 ccatcaaccg ctttaccatg gaagccaaac gtctgctcga cgtgctggat aagcaactgg
      301 cgcagcataa gtttgttgcg ggcgatgagt acaccattgc ggatatggcg atttggccgt
      361 ggtttggcaa cgtggtgtta ggtggtgtgt atgatgccgc tgagtttctt gatgcgggca
      421 gttataagca tgtacaacgc tgggcgaaag aagtaggcga acgtccggcg gtgaaacgtg
      481 ggcgtattgt taaccgcacc aacggaccgc tgaatgagca gttgcatgag cgccatgacg
      541 ccagtgattt cgagacgaat acggaagata agcgtcaggg gtaagggttg gtgttcgtcg
      601 cagcaagcca tccaggccgg ataaggcgtt cacgccgcat ccggcaatcg tgcacaatgc
      661 ctgatgcgac gctgccgcgt cttatcaggc ctacgaaagc taatcatcac gcgctggtaa
      721 tgtcgtaatc catttggcgc agtgcgtcta atgtggcttt ggcttcatct tcgtcgatga
      781 tgctcatggc aaatccgacg tgtaccagca cccactggcc cagtagatcg gcagggttac
      841 cttcacaaat cagggcgata ttcacatcgc gcttgatacc acatacttca acctgcgcaa
      901 gctggtgaat atcttcaccg acagccagca cctggcctgg aacgccaata cacattatta
      961 actccggtta ttcaacttca atacttttga cgatcagcga atcgccggta tcgacacgca
     1021 accgctcgcc gtgacagagc ggacactgcg catcgtgctg atgaatctcc accacctggc
     1081 tgcaatccca gcaccaagcc tgggcgggtt tatagacgat atgtaaatcg cacccttgcg
     1141 ccaccgttcc gtggcagaca atttcaaaac taaaacggac ggcgctctcc tcaacgcagg
     1201 agagcgcgcc aatttccagc cacacggcgg tgacgcgctt aacatcgtgc tgctccgcct
     1261 gccgttggat aatttcaacg gcgctctggc aaagagacaa ctcatgcatt ttcgccactc
     1321 ctgcgaccaa acagcagggc gcgacgccct gcgtgtggta catccggatt cgtgactggc
     1381 agcgaaagga tcattcgtgc gcagtcatcc gtcaggcgtt ggccctcttc aatcgacatg
     1441 ctgtgcgaaa gcggcgacat cagcgaacag gagagatatt gcgaaacacc gtccagttcg
     1501 ccaacggtaa aggtcatagt gccatacggc agttgcagac caattttttc actcactttg
     1561 cgcagcggcc agagttgatc cgggccgggg aagataactg cactcagcat ccacggggtg
     1621 atcacacacc ccgtccactg accttcgaac agcgtaaaat cagaaacata caccggcatt
     1681 gaaggatgca gaaaagagag atcgtgcatc gaacgccggg caatttcttc aaacgctgcc
     1741 tgtacttgcg ccttcgggga ggtctggaaa cctgctatct cttcagtcat gaatcgcctc
     1801 ccgtgggatg gcttccacgc cagattcacg cagcgcagcc agaacctgct caagcgcagg
     1861 ttcaatcatt gcttcaaccg tcggcgttaa gccgatgtgt ggctccagcg attccgggat
     1921 cacgccgacc agggtcagct ttttcggaaa ctcgccggtg aagcgcaggg ccgacaagac
     1981 gtcggccagg ccaagctgat gcggagagat tttgttggta aacaacgccg gaacttcttc
     2041 atcccgcagg atcatcatcg ttcccggcgc gttctttttc gagacaatgg catccgcaat
     2101 aatcaaatga tcgcgatttg ccatgtcgcc aagcagctcc attcccgccg tgccgccatc
     2161 gaggatctca acataatccg gcagaatgta tcgttgctct aacgcttcga caatccgcac
     2221 accgatggct tcatcggtca gcaaaatatt gccgacccct aagactaaaa tacgcattac
     2281 agaaccttca ctgaaaccac ttcgttgccg tcagcatcca ctacgtgtac cgcacaggcc
     2341 atgcacgggt caaaggagtg aatggtacgc accacttcca gcggtttatt cggatcggca
     2401 accggtgtac ccaccagcga ctgctcgtaa ggaccgacgt catcattgaa gttacgcgga
     2461 ccagagttcc aggttgatgg aacaaccgcc tggtagttgc tgatgatacc gtctttaata
     2521 accatccagt gagagagcat accgcgcggc gcttcgagga agccaacacc tttgaattca
     2581 cccgttgccg gaatgttcgg cttcacaaag gtggtgtgat cgcctttgcc gatattggtg
     2641 atcagtgcac tgtattggtt ttgcaggata tcctgcaatt cacagcagtg aacggtacga
     2701 ccaataatac ggcccagcgt ggagtgcagc tgtgccactt ccagcgtgtt gccagtcagt
     2761 ttctgataaa tcgcaacgat ttcattcagt ttgttctggg tagattcgcg acctgccgcc
     2821 agtttcacca gcatattagc cagtggcccc acttctaccg ttttgccgta gaaagtcggt
     2881 gatttcaccc aggaatattt cccgtcgtca gaccaaccat cataagccgg aatggtggtg
     2941 ccttcccacg gtgcctgcgg cgcttcgtct ttataccagg agtgcttcgc gctttcctga
     3001 atgcctttga tcaggtattc atcggaatga gaagtgatcg gacgatacga ggacagatcc
     3061 gcattctcaa tgtagccgcc cgggaacagg aagctgccgt ttttactgtc ggtcgggaat
     3121 tccggcacgc tcaggtagtt caccgcacct ttaccgcgtg tcagccattc cgggtagaac
     3181 gcggcaataa ctgcggtatc aaccttataa acctgctcaa caaagtcgct cagtttgtcg
     3241 atgaaagact tgatgtacat caggcgctca aggttcagca cgcccaaacc gtcgaggttg
     3301 atcgggttcg cgacaccacc taccgccagg ttctgaatgt gcggcgtttt accgcccagc
     3361 agcgccacga cgcggttagc gtcacgctgg cactccaacg cttgcaggta gtgcgctacc
     3421 gcaatcaggt tcacttccgg cggcagtttc atcgccggat gaccccagta gccattagcg
     3481 aaaataccca actgaccgct ggcaaccaga tctttgatct tgttctgaac tttggtgaac
     3541 tcttccggac tgttcaggtg ccaggtcgaa acgcctttca gcatttcgga ggctttggtt
     3601 gggtcagctt gcagtgcaga agtgatgtcc acccagtcca gcgccgaaag ctgatagaaa
     3661 tgaacaatat ggtcatgcgt ggtgtgcgca gccagaatga tgttacggat gtattgcgcg
     3721 ttaaccggaa cgtcgatatt cagcgcactt tctgccgcac gaacggaaga cagcgcgtga
     3781 gtggtagtac atacgccaca gatacgttgc acaatcatcc atgcatcgcg cggatcgcgg
     3841 tttttcacga tctcttccat gccgcgccac atggtaccgg aagcccatgc tttcgaaacg
     3901 acgccatttt cgatttcgca atcgatgcgt aaatgcccct caatacgggt taccggatca
     3961 atagtaattc tctggctcat gctttgctcg cctcatgacg attatgatcg ttttgtttta
     4021 aaggaggaag tatcggcagt agacgaatga gtacgatgta agcgcaaatc tcaatagcca
     4081 caaaaccaat agaaatcaac agttcttccc aggtcgggaa gtaggcgtaa ccgccgcccg
     4141 ggttgaatgc caccagcgaa taggtcagac gccaggttgc acaacctaac agtgcgctca
     4201 gtgctgacag gaacagcatg cgggaatcat tacgcagctt cgccacacgc agaacgacca
     4261 gcgggaagag catcagcagg acttcaatcc agaacatcac ggagtagaag tcaccggcaa
     4321 acgctaacga cagcttgtcg cgatagataa gctcgccaaa gcgcagcacg atgaaaatcg
     4381 ccagcaacac actgatggtg ttggtcagct taacaaacag actcttttca tccggaccgt
     4441 tgccacgcag acccgcctgc accagcgaac cttcaaagat gacaatcgag aagcccatga
     4501 tgaacgccgt cagcagcgag aacagcggca acatttcata gctctgccac aacggatgca
     4561 ccttgtagcc cgccgagatc atcagcgacc ccattgaaga ctggtgcatg gtcggcagca
     4621 gcgcaccgag cgcgatgatg aagaacatca ccttatttag tcgctgtagc gacaccttcc
     4681 accccagacg ttcaaacagt gccggagcaa actccagtgc catcacgccg atatagatgg
     4741 tcatacagac cgccgtctcg aacagtaccg agttcacgtt gaagtgaccc ggaatgtaga
     4801 agtacggcag gttccagtag cgacccacgt cgatagtgat cgacaagcca cccagtgagt
     4861 aaccaaacag actcgccaac agcgccggac gcaccagcgg atggtattgc ccacggttaa
     4921 agacgtatac cgcccacgcc agcgcccagc cgccacaggc aaagccggtg ccaatcagca
     4981 ggtcaaacgc gatccacacg ccccacggga agccgccgtt caggtcagag acagagccca
     5041 gaccgaacac cagacgcttc acaatcagga gcatacagat gacgattaac ggtccaaaaa
     5101 tcatgaccgg tttactgatg attttgccgc ccagcggttg tggatcatga ctcatgatcg
     5161 tctcctccgt cgtgatggtc gtttttggtg ttgcgacgaa ccagcacggt taagcccgcc
     5221 agcacagcca gtggtagcat catgccttta tacagggtgt gttgaatatt ttcggaacgc
     5281 gcaccggtag aaagatcgtc cagtttcggc aggtcgagat tttcataagg cacacccgtc
     5341 agtaccagaa cctgagtacc gccgccctct ttctcgccgt acagatgcgg ataatatttc
     5401 ggcaccgtat gcaggtaagt gtcgccagat ttcagcgtct gacgcggata gtggtattcg
     5461 ctgccaggct tcagcgccag acgttttttc gcctccgcca tcagctcttc acgcgtaccg
     5521 aaaatcaccg cgcccgccgg gcacacttct acgcagccag gtagaccgcc tttatcgaga
     5581 cgttccacac ctttctggtt gcacagctcg cacttatgca gcgcaccaaa cgggttgttg
     5641 tagtcgtact tcggcacgtt gtacggacag gcgaccatgc agtaacggca gccggtgcac
     5701 acatctttgt cgtaatggac aatgccggtt ttcggatctt ttttcagtgc agagaccggg
     5761 cacacagaga cacagttcgg atcgacgcag tgcatacact gtttcttaat gtacgcgtag
     5821 ccgttctcct cctggtcttt gttgacccct gtgccgctgg tccacacctg aatgatgtta
     5881 ttggtatacg gcgacagttt gtcgttgttc gaccaggtct gttccccttg cgggttacgt
     5941 tcagggaaat tgatatcctg acacttggtg acgcaagcct ggcagcctac gcacaaggtc
     6001 gagtcgtaca acatccccag cgatcccgga attggcgggc ggttttcagc agccgcatga
     6061 ctgacagacg gcagcgcgcc cgtcagcaat gccccgcagg aggctgcttt aataaaatta
     6121 cgtctgttca cggttattct ccccgtgagt cagcgttatc tttcttttgc tgacgaccca
     6181 gttcacgcac cgccatcacg ctgacaccgg caaccaaccc aaccacaccg ccgagcaaac
     6241 caatagcgcc tgcagagacg ttgccgccct ctttagcgtt aacatccggt ttctgtgaac
     6301 gcggagtttg attttcgacg ttggcaagct gatggatgcc tttatggaag ccgatacctt
     6361 cttcgttaca gccatagcac gggtgaccaa tcgccaccgg ccacacaccg ccaacatcgc
     6421 agaattgcag cgttgagcag ttgccgtaag tttctggccc tttacagccg aggtggtaca
     6481 ggcaccagcc ttcgcggtgg ccttcatcac cgaactcttt ggcaaaacga ccagcatcga
     6541 agtgcgggcg acgttcgcag tgttcgtgaa tcagacggcc ataggcgaag gtcggacggt
     6601 ttttgtcatc cagtttcggc ggtttgccgt aagtgatgat gtgcgcaacg gtcgcgagga
     6661 agttgtgcgg gttcggcggg cagcccggaa tattgataac ggttttgcct ggcagaactt
     6721 cttgcaggct gactgcgcca gttgggttaa ctccagctgc ggcaacaccg ccccacgcag
     6781 agcaggaacc gatagcgata atggctgctg cgccttccgc cgctttgcgg atgtgatcca
     6841 caatcggctc accggcaacc atgcaataaa taccgttatc ttttaatggg atggaaccat
     6901 ccaccactaa cacatactgc cctttgtact tctcgagagc gttatgtttg ttctcttcga
     6961 cctgatgacc gaaggcggcg gaaagcactt cgtgatactc cagagagata gtctccagta
     7021 cgaggttttc taccgttgga tgcgttgcac gaagcagaga ttccgtacaa ccggtgcact
     7081 cctgcgcgcc aatccagata actggcggac gctgcgggtt agtaaccgat tcggccatct
     7141 ctgcagcggc tttgctactt aaccccatgg tggtggctaa tgctgcacaa agcttcatga
     7201 aatcacgacg gttaatgccg tgagaatgga tgagggtgtt atctccagtc atttatagtt
     7261 attccgttgc gaagacctgg catatatttt gcctcaatcg caaaatcaat aatgcgatcg
     7321 atgcgccatt taccacacat ttattatggt tatcgatatc atgatactgc ggcggggcgc
     7381 taaaacgaag ggaagaagca ttagtgtaat taattaaagc aagataatac gtatgtttga
     7441 tcaattttcg aggcgataac cggccataaa aaagcgcaac gtagaacagg aattattctc
     7501 acgaaagaaa tccattacca tctctttatc cagtccatag cggcgcgtca gaatacccgc
     7561 ttcccaggcg ctaagctggc gatctccggt cttttcgtac atccggtgtg agtagcctaa
     7621 tacaaaaccg cgtttataat cggcacagaa ttttgtcaca ttaaccgcac tgtcggcatg
     7681 cgttgctttt aatcccgcca ttaagccttt accaaaatgg ttattcatcg ttcacctcat
     7741 tcgctatata ttgtcatata tagcgatatt ttaggcaaag aacgactttt gcgcacgcta
     7801 ttttttcatg cttgtttaag acgtaatccc gtaagagata aacctatcag gagagatatt
     7861 tatcgaacca tttcagtgtc ctttgccagg caagatcggc ggcagatttg tcataacggg
     7921 gcgtggaatc attatggaat ccgtgattaa cccccggata gatatacgcc tcataaacct
     7981 tattattggc tttcaacgcc gcctcgtaag caggccagcc ctcgttgatt cgggtgtcca
     8041 gttccgcgaa gtggagtagt aaaggcgctt caatcttcgc cacatcggca gtgggtgcct
     8101 gacgaccata aaacggcacc gcgcaggcca gttccggata cgcgacagcc gccgcgttcg
     8161 atacgccacc gccatagcaa aatccggtaa tacccacttt gcctgtcgct tgcggatagc
     8221 gttgcataaa ctcaattgcg gcaaagaaat cattcatcag tttgttggat caacctgctg
     8281 ttgcagctca cgacctttat catcatttcc cggataacct ccaacggaac ttaagccgtc
     8341 aggtgccagg gcgatatacc ccgccttcgc cactcgccgt gccacatctt cgatatacgg
     8401 attcagtcca cgattctcat gcaccaccac tacggctggc gttttgccgc tcatctttgc
     8461 gggcttcacc agataacccc gcacctcgcc gtgaccattt ggcgaaggat acgtgatgta
     8521 ctcagcaaca atttccgggt cggtaaactc tacctgagtc gccagcgcat aatttggctt
     8581 gagcaaatca aacaacgcta atgccgtcat cccgcctact gcacttcgcc gcaaggttga
     8641 ggaactcacg tttcgagatt ttcccgtgag cgtaatagtc atagtaatcc agcaactctt
     8701 gtgggaaatc tttggcggtt aaacgcggca tcgttgcact cctcagttgg tgttttttta
     8761 agcaaagcat aagcacgtgt ttttgcccag tttttcgtca ctctgtgagc cagactacgg
     8821 gatacgcgct ggcgaatcgc taaactagaa acattgtttc gaaattgaac ggtggaaagg
     8881 agaggtcatg gtctggttag cgaatcccga acgttacggg cagatgcaat accgctattg
     8941 cggaaaaagt ggtttacgcc tgcccgcgtt atcgctcggt ttatggcaca atttcggtca
     9001 cgttaacgcg ctggaatcac agcgtgcgat cctgcgtaaa gcgtttgatt tgggcattac
     9061 gcactttgat ttagccaaca attacgggcc gcctccagga agcgcagaag agaactttgg
     9121 tcgcctgctg cgggaggatt ttgccgctta tcgcgatgaa ctgattatct ctaccaaggc
     9181 tggctacgat atgtggcccg gcccttacgg ctctggcggt tcacgtaaat acctgctcgc
     9241 cagcctcgac caaagcctga agcgtatggg gcttgagtat gtcgatatct tttactctca
     9301 tcgcgtcgat gaaaatacgc cgatggaaga aaccgcctct gcgctggctc atgcggtaca
     9361 aagcggtaag gcgctgtatg tcgggatctc ctcttactcg ccagagcgga cgcaaaaaat
     9421 ggtcgagttg ctgcgcgagt ggaaaattcc gctgttaatt catcaacctt cgtacaattt
     9481 actgaaccgc tgggtggata aaagcggcct gctggatacc ctgcaaaata acggcgtggg
     9541 ctgtattgcc tttactcctc tggctcaggg attgctgacc ggaaaatatc tcaacggcat
     9601 tccgcaagat tcacggatgc atcgtgaagg gaataaagtt cgtggtctga caccgaaaat
     9661 gcttaccgaa gccaacctca acagcctgcg cttattgaat gaaatggcac agcagcgtgg
     9721 acaatcaatg gcgcaaatgg cgttaagctg gttgctgaaa gatgatcgcg tgacgtcggt
     9781 attgattggt gccagccgcg cggagcaact agaggagaac gtgcaggcgc tgaataatct
     9841 gacatttagc accaaggagc tggcgcagat tgatcagcat atcgccgatg gcgagctgaa
     9901 tctgtggcag gcgtcttccg ataaatgacc tgttaataac gggcgcgcga accgcgcccg
     9961 aatcagatca gtgattatga cgagtcagtc ggtcaagata gcccatcaca aatgcagaaa
    10021 gcacaaacgt cagatggata atgacgtacc acatcagttt gttatccggg acatttttcg
    10081 catccataaa gacgcgcagt aagtgaatgg aagaaattgc cacaatcgac gctgctactt
    10141 tgtttttcag cgacgttgcg tccattttcc ccagccagtt cagcttctct ttgttctcgg
    10201 agatatccag ctgtgagacg aaattctcat aaccggaaaa catcaccatc accagcaaac
    10261 cgccaaccag cgtcatatcc accagcgaca gcaacacgag gatcaaatct gattccgcca
    10321 tcgagaagat attcggcagt acgtgaataa tctcctggaa gaacttcagc gccagggcaa
    10381 ctaacgccag cgaaaggcca aagtacacgg gggcaagcag ccagcgagaa gcatacattg
    10441 cattttcaag aaaacgttcc atacattcct gtcgtgtagt taaaacgggc aacagtatat
    10501 cgcaattgag taaacagcac gcaacagcaa atcaacatat acgttaaacc tttgtcgcat
    10561 aattctgagg tttagggatc ttcctggttc ccttatcaac gcatcgagaa cgtctaccct
    10621 taaaggacgt tgaacctgaa gggagaaaaa cgatgtctca tttaaaagac ccgaccacgc
    10681 agtattacac tggtgaatat cccaaacaga aacaaccgac gccaggcatc caggcgaaga
    10741 tgacaccggt accggattgc ggcgagaaaa cctatgttgg tagcggtcgc ctgaaagatc
    10801 gtaaagcact ggtgacaggg ggcgattccg gaataggtcg cgctgccgcc atcgcttacg
    10861 cgcgtgaagg ggctgacgtg gcgatcagtt atcttcccgt ggaagaagaa gacgctcagg
    10921 atgtgaaaaa gatcattgaa gaatgcggac gcaaagccgt tctgctgcca ggcgatttaa
    10981 gcgatgagaa atttgcccgt tcgctggttc acgaagcgca caaggcgtta ggcgggctgg
    11041 atattatggc gctggtcgcc gggaaacagg ttgccattcc ggatattgca gacctcacca
    11101 gcgaacagtt tcaaaagacc tttgccatta acgttttcgc gctgttctgg ctaacccagg
    11161 aagcgatccc cctgctaccg aaaggtgcaa gtatcatcac cacttcgtca atccaggcat
    11221 accagccaag tccgcattta ctggactatg cggctacgaa ggcggcgatt ctgaactaca
    11281 gccgtggctt ggcaaaacag gtcgcggaga aaggtattcg ggtgaatatt gtcgcgccag
    11341 gcccgatctg gacagcactg caaatttccg gcggacaaac gcaggataag atcccgcagt
    11401 ttggtcagca aacgccgatg aaacgtgcgg ggcaaccggc ggaactggcc cctgtatatg
    11461 tttatctggc aagtcaggag tcgagctacg tcaccgcaga agtgcacggc gtgtgcggcg
    11521 gcgagcattt aggttaaaaa aatgcccggt tgtgaaaagc aaccgggcat cattgtgaat
    11581 tcactcttac ctgatgtggc gaaaacgcct tatccgccta caaacgcatg aagattcaac
    11641 atgttgcaat agattttgta ggcctgataa gcgtagcgca tcaggcattg agcacctaat
    11701 gccggatgcg tcgtgaacgc cttatccggc ctacaaacgc acgaagattc aacatgttgc
    11761 aatagatttt gtaggcctga tgagcgtagc gcatcaggca attctacttt acttcgcttt
    11821 ggcggtttct tcgccgacca gacctatctt caggtaaccc gcctgatgca gcgtatccat
    11881 taccttcatc aacgtctcgt aatcgacggt tttgtccgct cggaagaaga tggtggtgtc
    11941 tttcttgcct tcggttaacg cattcaacgc cgtaatcatt gtttcatcgg tgaccggatc
    12001 gttaccgata aacatcgagt tgtctgcctt caccgacaga taaaccggtt tttccgggcg
    12061 cggctgcggc gtgctggtag aagcaggcaa gttcaccttc acatctaccg tcgctaacgg
    12121 tgccgccacc ataaagataa tcagcagaac caacatcacg tcgataaacg gcgtcacgtt
    12181 gatatcatgc atttcgccgt tatcgtcgag gttttcgtta agatgcattg ccatcggata
    12241 ttatcctgcg cgtaattttt gtgcgacacg aaccggatgc gcagcggcgc tggcttccag
    12301 atccaggtca cggctttgca gcaacaatac ctgcgctgca acatcaccca gcatcgcttt
    12361 aaagccgcca atctggcgtg caaatacgtt atagataacg accgcaggaa tcgctgccac
    12421 gaggccgatt gccgttgcta acagagcttc tgcgataccc ggcgcaacga ctgccaggtt
    12481 agtggtctgc gtttgcgcga taccaataaa gctgttcatg atgccccaga ccgtaccaaa
    12541 cagaccaacg aacggagaaa tcgcgccgat ggttgccaga tagccgttac cgcggcccat
    12601 ttgacgaccc actgcggcga cccgacgctc cagacggaag ctggtacgtt ctttaatacc
    12661 ttcgttatcg tcgctgcctt ctgacagttc cagctcattc tgcgcttcat tgagcaaatg
    12721 caggcttaag cttttgctac caaaatcagc ggcgatatcg ttggcctggt ttaaggaacg
    12781 cgcttcagcc agcagttgct gctcgcgctt aaggcgacgc ttctgattga agaactctac
    12841 gctcttactg aagaagattg cccaggtgac tacggaggcc aaaataagcc caatcatcac
    12901 gcacttaacg acaatatcgg cgtgctgata cataccccag acggaaaggt ccgtctgcat
    12961 taaattatta cccactgtgt atctccagga cgcaagtcac aaaatctgcg cataataata
    13021 tcaaaacgac gtcgaattga tagtcgttct cattactatt tgcatactgc cgtacctttg
    13081 ctttcttttc cttgcgttta cgcagtaaaa aagtcaccag cacgccattt gcgaaaattt
    13141 tctgctttat gccaattctt caggatgcgc ccgcgaatat tcatgctagt ttagacatcc
    13201 agacgtataa aaacaggaat cccgacatgg cggacaaaaa gcttgatact caactggtga
    13261 atgcaggacg cagcaaaaaa tacactctcg gcgcggtaaa tagcgtgatt cagcgcgctt
    13321 cttcgctggt ctttgacagt gtagaagcca aaaaacacgc gacacgtaat cgcgccaatg
    13381 gagagttgtt ctatggacgg cgcggaacgt taacccattt ctccttacaa caagcgatgt
    13441 gtgaactgga aggtggcgca ggctgcgtgc tatttccctg cggggcggca gcggttgcta
    13501 attccattct tgcttttatc gaacagggcg atcatgtgtt gatgaccaac accgcctatg
    13561 aaccgagtca ggatttctgt agcaaaatcc tcagcaaact gggcgtaacg acatcatggt
    13621 ttgatccgct gattggtgcc gatatcgtta agcatctgca gccaaacact aaaatcgtgt
    13681 ttctggaatc gccaggctcc atcaccatgg aagtccacga cgttccggcg attgttgccg
    13741 ccgtacgcag tgtggtgccg gatgccatca ttatgatcga caacacctgg gcagccggtg
    13801 tgctgtttaa ggcgctggat tttggcatcg atgtttctat tcaagccgcc accaaatatc
    13861 tggttgggca ttcagatgcg atgattggca ctgccgtgtg caatgcccgt tgctgggagc
    13921 agctacggga aaatgcctat ctgatgggcc agatggtcga tgccgatacc gcctatataa
    13981 ccagccgtgg cctgcgcaca ttaggtgtgc gtttgcgtca acatcatgaa agcagtctga
    14041 aagtggctga atggctggca gaacatccgc aagttgcgcg agttaaccac cctgctctgc
    14101 ctggcagtaa aggtcacgaa ttctggaaac gagactttac aggcagcagc gggctatttt
    14161 cctttgtgct taagaaaaaa ctcaataatg aagagctggc gaactatctg gataacttca
    14221 gtttattcag catggcctac tcgtggggcg ggtatgaatc gttgatcctg gcaaatcaac
    14281 cagaacatat cgccgccatt cgcccacaag gcgagatcga ttttagcggg accttgattc
    14341 gcctgcatat tggtctggaa gatgtcgacg atctgattgc cgatctggac gccggttttg
    14401 cgcgaattgt ataacattgc cacttttgga caattttgca gacattttat tgtgaaaagt
    14461 cttaaattgt tgcgtccggg atcaaggcgt cccggacgat tcaggagtac aataggcaga
    14521 taaaggctta aacgctgttc cacaggaaag tccatggctg ttattcaaga tatcatcgct
    14581 gcgctctggc aacacgactt tgccgcgctg gcggatcctc atattgttag cgttgtttac
    14641 tttgtcatgt ttgccacgct gtttttagaa aacggcctgc tgcccgcctc atttttgcca
    14701 ggcgacagct tgttgatact ggcaggcgca ttgattgccc agggggttat ggattttctg
    14761 cctacgattg cgattctgac cgccgcagca agtctgggct gctggctaag ttatattcag
    14821 gggcgctggt tagggaatac caaaacggtg aaaggctggc tggcacagct tcctgctaaa
    14881 tatcaccagc gcgccacctg catgtttgac cgccacggtc tgctggcgct gctggctgga
    14941 cgttttcttg catttgtccg tacgctgctg ccaaccatgg cgggaatttc cggtctgcca
    15001 aaccgccgct tccagttttt caactggtta agtggattgc tgtgggtcag cgtggtaacc
    15061 agttttggct atgccttaag tatgattccg ttcgttaaac gccatgaaga tcaggtaatg
    15121 acgttcctga tgatcctgcc aattgccttg ttaaccgctg gcttgttagg cacgctgttt
    15181 gtggtgatta aaaaaaaata ctgtaacgcc tgacgatttt ccccgttccc ggttgctgta
    15241 ccgggaacgt atttaattcc cctgcatcgc ccgcattctt gccgcatctt cccccggcgt
    15301 cacaccgaag taacgtttaa actcacggct aaattgcgat gcgctttcat agccgacgcg
    15361 catcgctgct gcgctggcct tcatgccgtc atggatgatc atcatccgcg ccttatgcag
    15421 acggtaattc ttcaaatact gcaacggcga ggtactggtg acagacttaa aattatggtg
    15481 gaacgccgat acgctcatgt tggcttctgc cgccagttgc tcgacgctca ggttttcggt
    15541 gtatttattc tcaatccgtt tcagcacgcg gctaatcaga ctgaagtgag tctggcgact
    15601 gaccagcgcc agtaacgcgc cgccgcaagg tccggtcagc acgtagtaca gaatttcgcg
    15661 gatgatctgt ttgccgagaa tacgcgcatc cagtggtcgc tccatcacgt cgagtaaccg
    15721 ctccgccgcg cataaaatct cttctgataa cgtggcggag ttaatcccgc tggctgccat
    15781 cgacggctgg aaatgctcat cttcgccaat gtccatcaac agttcctgta actgcaaaat
    15841 atcgacattg agacgcaacc ctgccagcgg cacctctgac gtggcatagg tttcgcactc
    15901 aaacggcaac ggcaccgtca gcagcaggta ttcattggca tcataacgaa acacgcgttc
    15961 attgatataa ccgattttat gcccggaaaa gagaattatg atgccaggct cgtacatcac
    16021 cggtgtacgt gcgaaaggcg tctcgccata caacaaacgc acatcgggca acagttctga
    16081 caaactattt tctttatttt tcagtttatt aactttatcc gccagcaagc ggcaaatctc
    16141 ttcacgtttc atatcgcgta atttcttagg aataatgcgg caatttgatt gtgcgcaatt
    16201 ttgtagcatt tctccagcac tctggagaaa taggcaagac attggcagaa atgagcattg
    16261 agagccaggg cgctggcgat cacaatgaaa aacatcaggc agatcgttct ctgccctcat
    16321 attggcccag caaagggagc aagtaatgaa caactttaat ctgcacaccc caacccgcat
    16381 tctgtttggt aaaggcgcaa tcgctggttt acgcgaacaa attcctcacg atgctcgcgt
    16441 attgattacc tacggcggcg gcagcgtgaa aaaaaccggc gttctcgatc aagttctgga
    16501 tgccctgaaa ggcatggacg tgctggaatt tggcggtatt gagccaaacc cggcttatga
    16561 aacgctgatg aacgccgtga aactggttcg cgaacagaaa gtgactttcc tgctggcggt
    16621 tggcggcggt tctgtactgg acggcaccaa atttatcgcc gcagcggcta actatccgga
    16681 aaatatcgat ccgtggcaca ttctgcaaac gggcggtaaa gagattaaaa gcgccatccc
    16741 gatgggctgt gtgctgacgc tgccagcaac cggttcagaa tccaacgcag gcgcggtgat
    16801 ctcccgtaaa accacaggcg acaagcaggc gttccattct gcccatgttc agccggtatt
    16861 tgccgtgctc gatccggttt atacctacac cctgccgccg cgtcaggtgg ctaacggcgt
    16921 agtggacgcc tttgtacaca ccgtggaaca gtatgttacc aaaccggttg atgccaaaat
    16981 tcaggaccgt ttcgcagaag gcattttgct gacgctaatc gaagatggtc cgaaagccct
    17041 gaaagagcca gaaaactacg atgtgcgcgc caacgtcatg tgggcggcga ctcaggcgct
    17101 gaacggtttg attggcgctg gcgtaccgca ggactgggca acgcatatgc tgggccacga
    17161 actgactgcg atgcacggtc tggatcacgc gcaaacactg gctatcgtcc tgcctgcact
    17221 gtggaatgaa aaacgcgata ccaagcgcgc taagctgctg caatatgctg aacgcgtctg
    17281 gaacatcact gaaggttccg atgatgagcg tattgacgcc gcgattgccg caacccgcaa
    17341 tttctttgag caattaggcg tgccgaccca cctctccgac tacggtctgg acggcagctc
    17401 catcccggct ttgctgaaaa aactggaaga gcacggcatg acccaactgg gcgaaaatca
    17461 tgacattacg ttggatgtca gccgccgtat atacgaagcc gcccgctaag ctttttacgc
    17521 ctcaaacttt cgttttcggg catttcgtcc agacttaagt tcacaacacc tcaccggagc
    17581 ctgctccggt gagttcatat aaaggaggaa cgtatggcta atccaaccgt tattaagcta
    17641 caggatggca atgtcatgcc ccagctggga ctgggcgtct ggcaagcaag taatgaggaa
    17701 gtaatcaccg ccattcaaaa agcgttagaa gtgggttatc gctcgattga taccgccgcg
    17761 gcctacaaga acgaagaagg tgtcggcaaa gccctgaaaa atgcctcagt caacagagaa
    17821 gaactgttca tcaccactaa gctgtggaac gacgaccaca agcgcccccg cgaagccctg
    17881 ctcgacagcc tgaaaaaact ccagcttgat tatatcgacc tctacttaat gcactggccc
    17941 gttcccgcta tcgaccatta tgtcgaagca tggaaaggca tgatcgaatt gcaaaaagag
    18001 ggattaatca aaagcatcgg cgtgtgcaac ttccagatcc atcacctgca acgcctgatt
    18061 gatgaaactg gcgtgacgcc tgtgataaac cagatcgaac ttcatccgct gatgcaacaa
    18121 cgccagctac acgcctggaa cgcgacacac aaaatccaga ccgaatcctg gagcccatta
    18181 gcgcaaggag ggaaaggcgt tttcgatcag aaagtcattc gcgatctggc agataaatac
    18241 ggcaaaaccc cggcgcagat tgttatccgc tggcatctgg atagcggcct ggtggtgatc
    18301 ccgaaatcgg tcacaccttc acgtattgcc gaaaactttg atgtctggga tttccgtctc
    18361 gacaaagacg aactcggcga aattgcaaaa ctcgatcagg gcaagcgtct cggtcccgat
    18421 cctgaccagt tcggcggcta acatgcaaat tctcccggtg gcggtaatgt tccgctaccg
    18481 gacttttcag aaatcattta ttcccctcgc gtcccgcccg ttgttactct tccttgttca
    18541 ggaatgccaa atataaggac atcatcatgc agagccggaa gctcttaaaa gaacaactca
    18601 tctatatccg ggataaacgc aacggagagg tgaaaaacag atgaaaataa tacttctgtt
    18661 tttagcagcc ctggcaagtt ttaccgtaca cgcacagccc ccctcacaga ccgtagaaca
    18721 aacagtccgg catatttatc agaactataa atcagatgcc actgcctctt attttggtga
    18781 aaccggagag cgggcgataa cttctgcgcg tattcaacag gcgcttaccc tgaacgacaa
    18841 tcttacgctg ccgggcaata ttggctggct ggattatgat ccggtttgtg attgtcagga
    18901 ttttggcgat ctggtgctag aaagcgtcgc gataacccaa actgacgccg atcatgccga
    18961 tgccgttgtg cgctttcgta tctttaaaga tgataaagaa aagaccacgc agacactgaa
    19021 aatggtggcg gaaaatggtc gttgggtcat tgacgatatt gtcagcaatc atggcagcgt
    19081 cttacaagca gttaatagcg agaatgaaaa aacgctggcc gctttagctt cgttgcaaaa
    19141 agaacagccg gaagcctttg ttgccgaact ctttgaacat attgctgatt atagctggcc
    19201 gtggacgtgg gtggtttccg actcttaccg ccaggcggtt aatgccttct ataaaaccac
    19261 cttcaagacg gccaataatc ccgatgaaga tatgcaaata gaacggcaat ttatttacga
    19321 caatccgatc tgttttggcg aagagtcgct attttcacgc gttgatgaaa ttcgagtcct
    19381 ggagaaaacc gccgattccg cccgcattca tgttcgtttt acgctgacca atggcaacaa
    19441 cgaagagcaa gaactggttt tacagcggcg cgaaggcaag tgggaaatcg ctgattttat
    19501 ccgcccgaac agcggcagcc tacttaagca gattgaggca aaaactgccg ccagattaaa
    19561 gcaatgagct gaattaaata acaattagcc ggaacaataa ataaaaggga acactatatg
    19621 aaaacgattt tcaccgtggg agctgttgtt ctggcaacct gcttgctcag tggctgcgtc
    19681 aatgagcaaa aggtcaatca gctggcgagc aatgtgcaaa cattaaatgc caaaatcgcc
    19741 cggcttgagc aggatatgaa agcactacgc ccacaaatct atgctgccaa atccgaagct
    19801 aacagagcca atacgcgtct tgatgctcag gactattttg attgcctgcg ctgcttgcgt
    19861 atgtacgcag aatgataaaa aaatccccgg tagcgtgtca gttgccgggg atatttttta
    19921 acgtccaacc gccgctttag gccgtttctt cgcaccagca ttcaccggac gagattgcgt
    19981 agacgacgct ttttttgccg tagcaggcgt ctgacgctgg gtcgccatcg gcgtatgttt
    20041 cgtcaacgcc ggacgggtat tgcggttctg gcgacgagct tcacgcatct cttcaatggt
    20101 tggcgcaggc actaagcaat cgcgacggct gccaatcaga tgctttttgc ccatcgcttc
    20161 cagcgcctgg cggattaacg gccagtttgc cggatcgtgg taacgcaaca acgctttatg
    20221 caaacgacgc tgtttgtcgc ccttcggtac gaagacgtct tcgctcttat aaccaatctt
    20281 cgccagcggg tttttcccgg tgtaatacat ggtggttgag ttcgccagcg gcgacggata
    20341 gaagttctgc acctggtcga ggcggaagcg gtgctttttc agccacagcg ccagattcac
    20401 catatcttca tcacgcgtac cggggtgcgc ggagatgaaa taggggatca gatactgctc
    20461 tttacctgcc tgttttgagt aagtatcgaa cagctcttta aagcggtcat agctgcccat
    20521 gcccggcttc atcatcttcg ataacggccc ttcttcggta tgttccgggg caatcttcag
    20581 ataaccgccg acgtgatggg tcgccagttc tttgatatag cgcggatctt ctacggctat
    20641 gtcataacgc acaccagagg caatcaggat ctttttaatg cctttcagat cacgcgcacg
    20701 gcgatagagg ttgatcgttg gttcgtggtt cgtgtccatg tgcggacaaa tatccggata
    20761 aacgcacgac aaacggcgac aagtttgttc agcgcgtggc gatttgcagc gcaacatata
    20821 catgttggca gttggcccac caagatcgga aatcacgccc gtaaaacctg gaacggtgtc
    20881 gcggatcgct tcgatctcat taatgatcga atcttcggaa cggctctgaa taatgcgccc
    20941 ttcgtgctcg gtgatagaac agaaagagca gccgccaaag cagccacgca taatgttgac
    21001 cgaaaaacgg atcatttcgt aagccggaat acgggcattg ccataggccg gatgtggcac
    21061 gcgcttgtat ggcagcgcaa aaacgctgtc catctcttcg gtagaaagcg gaatagcagg
    21121 cgggttgatc cacacatagc ggtcgccgtg tttttgcatc aatgcgcggg cacagcctgg
    21181 gttggtttcg tggtgcagaa tacgcgaagc atgggcgtac agcactttat cgcccttcac
    21241 tttctcgaaa gaaggcagca acacgtaggt tttttcccac ggtttcgggc gcggtggctg
    21301 cacggttacg gctttggctt cctgcttttt cggtgccacc ggtttgttat ccgcgcacgg
    21361 caaatcttca ccatacggat gcgggattgg gtcgattttt ccaggggtat caagacgggt
    21421 ggaatccacg ccgctccagc caggcagcgc ctctttcacg ataatcgcgg tattacgcac
    21481 atcgcggatt tcactaattg gctcgcccat cgccagacga tgcgccactt ccaccagcgg
    21541 acgctcaccg ttaccaaaca tcagcatgtc ggctttcgaa tccaccagca cggaacggcg
    21601 cacggtatcg gaccagtaat cataatgcgc ggtacggcgc agactagcct caataccgcc
    21661 gaggatcacc ggtacatctt tccacgcctc tttacaacgc tgggtataaa ccagtgtggc
    21721 gcgatccggg cgcttacccg cgacgttatc cggcgtgtag gcatcgtcat gacgtaaacg
    21781 gcgatcggcg gtataacggt tgatcatcga atccatgttg ccagcagtaa caccgaaaaa
    21841 cagattcggt ttacccagac gcataaagtc gtctttgctg ctccagtccg gctgggcgat
    21901 gatcccgacg cgaaagccct gcgcttccag catacgaccg caaatcgcca tcccgaagct
    21961 tgggtgatcg acatacgcgt cgccagtaac caaaatgatg tcgcagctat cccagccaag
    22021 ttgatccatc tcttcacgag acatcggcaa aaacggtgcc ggtccaaaac aggcggccca
    22081 gtactgcggc caggagaaca ggtcgcgatc cggttggatc agggagatag agctcatttt
    22141 gcttccagaa atgataaaaa aataatcaaa ggccggggat tataagccgg aacgaaagag
    22201 aaatcgaaag gtattccata ctcgccctcc tcgggcgagt atgaagatta cggtaccgga
    22261 ttgaccaaca gttgcccaat cgagccacgg tccgccattt ccagcgtctg actgttgaag
    22321 tagaacggga agtgcgccca ggaaggctga ccgaaataaa caagcagctc cacttgtccg
    22381 tcaacccaaa cggtatcttt ccagcctctg tcttccggga acggcatcgc gccattcacg
    22441 ttacggatct ggaacattac gccttcaata tggaacgctt gcggctcgtc cgcgcgtacc
    22501 gtccagcgtt cccacgttcc ttgctgcgcg gtgacatcaa tacggttgac gtcccacagc
    22561 tgtccattaa tacccgggtc atcacccaga ctgatatcgc gactgcgaat tggcgaacca
    22621 gccatgattt cagttggcag caagcgcatc ggaagactgt ctgtgaccag cggcagaagg
    22681 ccggttgggc gcagcgttag caccagggta gaaaccagaa tactggatgg ctcaaagaag
    22741 ccacgaatac gatcaacaat gctcgccgct tcgccacagg tgatcgacac ttcatcgccg
    22801 ttgctcatat ccaccagaat ctcgcggcgc tcgcccggtg ccagcgaaag ttgcttcacc
    22861 gatacaggag caggcaggaa tccctgatcg ccagaaatca catgtaacgg gcgaccatcg
    22921 ttcatctgta gttgatagcg acgagagttc gacgcgttca gcagtcgcaa gcgcacccag
    22981 ccacgcgaga cttcaacgta cgggctttgt acaccgttaa ccagcagcgt atcaccaaca
    23041 aagccgccgc ttcccggttc gttgtattct ggcgtaccaa agttatccag ccgtttatcc
    23101 tggataatga ccggaaaatc atccacacca taatggttgg ggataggcag cgacttgctg
    23161 acttcatctt ccaccagcca cattccggca aggccgttat agacctgctg agccgtgcgg
    23221 ttgggagtat tggcgtgata ccacagagta gctgcgttct ggcgaatggg cagtacgggt
    23281 gcccagtcag cgtttggcga catcatccgt gccggaccgc ccatcagcgg gcctggtacc
    23341 tgtagcccgg ccaccgtcat tgagacattt tctgtcaggc ggttgctgta aataagctta
    23401 acatcgtcgc ccttccagac gcggatagtc ggccccaggt aacgaccatt gattccccag
    23461 accgacgcgc gtgtccctgg cgtaaatgac cagtgcgcac gttgtacagt cataaacagc
    23521 ggttgcccac ggcgagattc aagtagcggc ggaacgggta gcggttgctg ttgcccggct
    23581 gcgctggcct tcaggggaac agcgcctgca caaagtgcaa tccccgatgc ctgaatgaac
    23641 tgacgccgac tgagtgacat atttgctcca tgtaaaactg gctaaagtaa taccgtgcag
    23701 gaaagtgttc cccgcaaaaa tacagattgc cgacttaaac ttttccggcg gcttcgcgtt
    23761 ctgcgacttc tttatcgagc tcggcgattt tttgttccat tatcgaacga caatgggcag
    23821 ccagctcacg aacctgatct ttgccatact gactgacgtc aattggcggc agcatttcga
    23881 caatcaccag accgttgtgc agtcgattaa gattaatctt attcgaagtt gtagagacgc
    23941 acacgggaat aatcgggacg cccgccgcaa ttgccgcgtg aaatgctcca gtcttgaacg
    24001 gtagcaggcc gcgaccacgg ctgcgggttc cttccgggaa catccagatg gaaatacggc
    24061 gttttttgaa gtgattcact acttccgcaa tggtgccgtg agctttagtg cgattgtttc
    24121 tgtcgatcaa taagttgccg gttaaccagt acaactgccc gaagaagggg atccacagca
    24181 agctcttttt acctaccgtc accgtcggcg gttgcacgat gttcgatgct gtcaccatgt
    24241 catagttgtt ctggtggtta gcgatataga tagcattgcc gtagctttca gcgtctgtag
    24301 gtttacggca ctcaactttc aggccaaaca gcggcgcaag acggccaaac atatgcccaa
    24361 aggtggccac atgtttcggg ttacgcgggc tgaaaaggca gtaaatggag ccgaatacac
    24421 agactaagat gctgtaaatc acggtaataa taagacgaaa gatatatagc ataacaccct
    24481 ctgaaggtct gagagactgg cattgtacgt cacctgaaat caggttaggg cattgttaaa
    24541 agccgctctc tggaaaagcg tattgttaat cgcaacgcat gaataaacaa cggtttcaag
    24601 ggaattttta tcgtttccgg gggttgaata cgctgccgga tgacgactta acgtttcatc
    24661 cggcgttcct tgcaagcggg aggaaacagc gccctccccg gcatattact cttcgctatc
    24721 accgctgctg gcacggcgag gagagtcgat ctcaacacga tcgatacgct gcaaaccgcg
    24781 catcaacgta ccgcggcgtc cacgttcgcc agtgactttc tgtaactctt ccgggcgcag
    24841 tttaattttg cgtttcccaa catgaatggt cagcgtgctt tgcggcggca gaacgtacaa
    24901 ttgcgccaga ccatcttctc cacgcgcggc ttctgccgat ggaatgttga taatcttgtt
    24961 gcctttgccc ttcgacagct gcggcagatc acttaccggg aacatcaaca tacggcctgc
    25021 ctgagtgatt gccagcagca tatcggaagc atcttcaatc accaccggcg gcataacatg
    25081 ggcattttcc ggtaaggtga tcaaagcctt acctgcacgg ttacgcgcca ccagatcgtt
    25141 aaaggtgcag acgaaaccgt aacccgcatc ggaagccatc agcagtttct gatcgtcgct
    25201 ttccatcagc atatggtcaa cggtcgcccc aggcggcaac gttaatttgc cggtgagcgg
    25261 ctcgccctga ccacgcgccg acggcagcgt aatcgggtca atggcatagc tacgaccggt
    25321 ggaatcaaca aacactaccg gttggttgct cttacctttc accgccgctt tgaagctatc
    25381 acccgcttta taattcaggc ccggcgcgtc gatatcatgg cctttagcgc tgcgtaccca
    25441 gcccatctgc gacagcacaa tggtgacagg ttcagacggc agcatgtcgt gctcgctcat
    25501 cgctttcgct tcttcgcgtt cctgcaacgg cgaacgacga tcgtcaccgt aggcttgcgc
    25561 gtctgcctgc agttctttct tcagcaggtt attcatttta cgctcggaag ccaaaatgcc
    25621 ctgcaactgg tcgcgctctt tttccagttc actctgctca ccgcgaatct tcatctcttc
    25681 cagtttggca agatgacgca gtttcagttc gaggatcgct tccgcctggg tttccgtaag
    25741 gccaaaccgc gacatcagcg ccggtttcgg ttcatcttca ttacgaatga tctcaatcac
    25801 ttcgtcgata ttgagaaacg ccaccagcaa accttcgagg atatgcaggc gcttgaggac
    25861 tttctccaga cgatagttca gtcggcggcg cacggtatcg cggcggaaca ccagccattc
    25921 ggagaggatt tccagcaggt ttttcaccgc cggacgacca tccagaccga tcatattaag
    25981 gttaatacga tagctctttt ccagatcggt ggtagcgaag aggtggttca tcacctgatc
    26041 catatccacg cggttggaac gcggcacaat caccaggcgg gtcgggttct cgtggtcaga
    26101 ttcatcgcgc agatcgtcaa ccatcggcag ctttttgttg cgcatttgcg cagcaatttg
    26161 ctccagtacg cgcgcacctg aaacctgatg cggcaatgcg ctgataacca ccgcgccatc
    26221 ttctttcttc cacaccgcgc gcatacgcac tgaaccacgt ccgttctcgt agattttacg
    26281 gatctcggcg cgcgaagtga taatttccgc ttcagtcgga taatccggcc cctgcacgat
    26341 atccagcagc tgatcgagcg tggttttcgg ctggtcgatt aatgcgattg ccgcctgagc
    26401 cacttcacgc aggttatgcg gtggaatatc ggtcgccatg ccgacggcaa taccggtggt
    26461 gccgttaagc aaaatgtttg gcagacgggc aggtagcatt ttcggctcct gcaaagtgcc
    26521 gtcgaagttt ggcacccagt cagccgtccc ctgccccagc tcgctcaata gcagctcgga
    26581 atatttcgac aaccgggatt cggtgtaacg cattgccgcg aacgatttcg gatcgtccgg
    26641 cgcgccccag ttcccctgac catcaaccag cggataacgg taagagaacg gttgcgccat
    26701 caggaccatc gcttcataac aggcgatatc gccgtgcgga tggtatttac ccagtacgtc
    26761 accgacggta cgggccgatt ttttaaattt ggcgctggca ttcaggccca gttcagacat
    26821 cgcatacaca atgcggcgct gaacaggttt cagaccatca ccaataaacg gcaacgcacg
    26881 gtccatgatc acgtacatgg agtagtttaa gtaggcgttt tccgtaaatt catgtagcgc
    26941 aaggcgctct gccatatcgc tcattaattc tgattcctca acttattcgc cagccttcaa
    27001 aggggcaata ttgccggaga tactacatta tctgccgcgt cgagtcacag gagatcagcg
    27061 tgaatagcgc cgccggacgt gctccgacgg cgataaaggc atcaatgtgc cttgatatac
    27121 aactctttgc tgtagacata atcctgggga ttatgcagcg gaaaaccgcc aacgtagggt
    27181 ttaagcagtt tgattaacgg ctgatagtag ataggaatca gcggtgcctg ttggttgatg
    27241 atcacttctg cctgctgata caacgcatta cgctttgtcg catcagtgat ctgcgtggcc
    27301 tggtttagta aggcgtcata ctgcgcattt ttccagtgac cgacgttttc ttcactatcg
    27361 cttttgagcg tgttcaggaa gctggaagca tcattgtacg tcgcatccca cgactgccga
    27421 gacagcatga aatcaccggc tcgtcgggca tcaagatagg ttttccactc cattgtgcgc
    27481 agcgtcacct gtgcacccag ccattttttc cattcggaag acaacgctat cgcggtcttt
    27541 tcatgcagat cgtacttgtt gtagaacagc tcaaagcgta gcggatgaga ggcgtcgtat
    27601 cccgcctgtt tcagcaaggc ttttgccatc gcgacgcgct cactcattgg cttttgcagt
    27661 tcatcgaacg tcgtcgcgct aaagcctttt acctctggcg gcgtcagcgt ggttgcgggc
    27721 gttctcaacc ccagtacctt ttgcgcaata agctgtcgat caaccgtaag atatagcgcc
    27781 cgacgcactc gcacatcgtt aaatggcggt ttctcaaggt tgaagttgta atattcgctg
    27841 ttcagacgcg gaataattcg tagctcgcca ggcagtgatt tttcaatggc gggaatttgc
    27901 tgcgccggaa cccaggtgag atcgacctct cccgcgcgat agcggttata gccggtgacc
    27961 gaattatcta gcgccagata ctcaacctgt tgcaatactg tatgttgcgc atcgcggtac
    28021 tttggatttt tgcgtgcagt aatcttttcg ttaactaccc actgatcaag cacaaaggca
    28081 ccgttgtaaa ccatgttctc tggcttactc cagctatcgc catgtttagc gatgacatga
    28141 tgaggaaccg ggaacagcgt cggccaggcg agcatcgtcg tgaaccaagg aaccggctgc
    28201 tcaagcgtaa cttcaagagt acgatcatcc gtcgctttga cacccagcga tgtaacatct
    28261 gctttacccg caacaatagc tgcggcattg ttaatgtgcg cctgtgccag atagccagca
    28321 aaagggcttg ccgttttcgg gtcaaccgcg cgctgccagc cgaggacaaa atcctctgcc
    28381 gtcagaggct gaccgtcgga ccactgcaaa ccgctacgca gatggaaaat atagcgcttg
    28441 ccgccgtcca gtatctccca gcgttcagcc tgagcgggct gcacctggcc ttcaccgtcc
    28501 atccatacca gaccttcaaa cagatccagc acaatctgcg cggcagtatt ctcctccacc
    28561 ttttgcgggt cgagcgtacc tgggtcgcta tgattgttgt aacgaaagac ttgttgcggg
    28621 gcgagcggtg tgttggcggg aacgtcagca gcgtagagag gagccgcact taccaggctg
    28681 accagccata ataaatttcg cgtatacatg gtattcctta ccggagaaat tataagccca
    28741 acaacaatac gcctgtggca ttgttcgctc aaacttatcg cgagtgattt ggctcacact
    28801 ccggtaaaga aaaaagcgag ttgcccccgc ttttccatta attaacggat ttcattcaat
    28861 agttctggat gcttatccag aacacgtaaa agtttgattg tggaaggatg aggttgggca
    28921 ttgccttttt cgtaacgcga aaacgcattt acacctcccc caaaaatttc gcttgcctct
    28981 ttttgggtaa gagagagctt ttttcgaacc ttcactataa attcaggtgc cactgtttcg
    29041 gcattcaccg aagcccgaaa tgcctttact tgcgccatga aagcatctga ctcttcttta
    29101 ttcatgatgc tctcttcgca atggacacaa tataaaccgt ggataccttt caatactgtt
    29161 tttcgtccac ggaaggtgta tggaatatct ttaatgccag aaaccatttc tccctggtgg
    29221 caaaccggac atttcatatt acttctcctt aaacgagacg atcagtacgt catgaattac
    29281 cgtaatttta agataaacct ggcctgtaac aagcctgggt ctgtaaacat cctgccagat
    29341 agtatgatca gagtaggtgg tcatgctttt ataaaagtcg ctctctgata atccaatgat
    29401 aacattacac ataccatcaa aatccaaacc taactcatct gcatttaaca gggcactacg
    29461 tgttgtacga acttgcccgg cattgacaag ttttttaacc tgactcaaac gtgtatgtgg
    29521 tgtgcgtttt tccataaccc ccgcctccct gttactttag ttataaccta aaaggttaat
    29581 tacagcaatg aaaaagcacc taaaaggtta gttagatgta cggagatagt gaccacacaa
    29641 aacgtattct ttaaggaaag tgattgacca tataagaaag tggcgcatta gtagcgccag
    29701 tttgaagcag gaatttataa gggaagctgg agtcaggcat cacgccaacg gcacataaac
    29761 atccgtttcc agtcgctgct ctgtcacccc ttcggcaaga ttggtgtagt gaaacagaat
    29821 cggtgcttta cgcattttct cgccgcttgc aggcagccag tggcgaatga tgccccatac
    29881 cgtgtgtgaa atatcgtcca gctcgccaac gtggcgggcc acggcataac gtccaccggt
    29941 aagttcacca ttgctcacac cataacgatt atcgggaatc ggttcgctaa cgctgccgca
    30001 gatatcaaag cgaaacgctt ccggtgcggt ggtggcaggg tcgtcccagg cgacgccaaa
    30061 agtctggctt tggttaacag gagaaagccc cgtctcttta cgccacatga taaatttcgc
    30121 cacgctgtag ttgagcaatt cagggctaca gcggtgcggc aacatcgcca caggtattga
    30181 tgggaaatcg ataatgttta catccagtgt caggtttgtc attttgcctc cctgcgaaat
    30241 tattcccggg aacgcgtccc gggagcggta acaattacgg atttactttg cggatctgtt
    30301 tgacgtcaat ttcaacagaa ttccagtctt tatcgacttc accctgaatc tcaaccgtat
    30361 ctttcggcgt caccgtcacg ccgttccagc gtttgtggtc gatatcaaca ttgatagtac
    30421 cgctggcatc tttgaacacg tagagatcgt cagagatgcg ttcaacgata ttgccgcgca
    30481 gggttaccca ggtgtcgtca cgcagggatt ttgcgctttc tacagtcgtt acgctgccgt
    30541 tcggcccctg gaatcctccg gcctgacttt gcgttgccga tgggccagaa aaaccgccct
    30601 gctctgctgc catcaccggt gcgctgcaca gggccattac tgcgattact gctgcgaatt
    30661 ttttcatgtt tattactccc tttaatgtct gtttccgagc atttaacaag atagtcctta
    30721 acaacttctt aagggaaaaa aataaaattt agtgctgtac agagcgcgtt acaacacggt
    30781 ttactggcag caaatacggt tatcgcaggg atgaaaaaat gcgaatttta ctgatagaag
    30841 atgacatgct gattggcgac ggcatcaaaa cgggccttag taaaatgggt tttagcgtcg
    30901 actggtttac acaaggtcgt cagggaaaag aggcgcttta tagcgcacct tatgatgcgg
    30961 tgatcctgga tttaacctta ccaggcatgg atggtcgcga tattttgcgc gaatggcgag
    31021 aaaaaggtca gcgtgagccg gtactgatcc tgaccgcgcg cgatgcgctg gcggaacgtg
    31081 tagaagggct gcgtctggga gctgacgatt atctgtgtaa accttttgcg ttgatagaag
    31141 tcgccgccag gctggaagct ctgatgcgcc gaaccaacgg ccaggccagc aacgagctgc
    31201 gccacggtaa cgtcatgctc gaccccggca aacgtatcgc cacgctggct ggcgaaccct
    31261 taacactgaa accaaaagaa tttgccctgc tggaattact gatgcgtaac gctggtcggg
    31321 tactgccgcg caaactgatt gaagagaaac tgtatacctg ggacgaagag gtcaccagta
    31381 atgccgttga agtgcatgtg catcatctgc gacgcaaact cggtagtgat tttattcgta
    31441 ccgtgcatgg tattggttac acattaggtg agaaatgaaa tttacccaac gtcttagtct
    31501 gcgcgtcagg ctgacgctaa tctttttaat tctggcctcg gtgacctggc tgctttccag
    31561 ctttgtcgcc tggaaacaaa caacggataa cgtcgatgaa ttgttcgaca cccaactgat
    31621 gctgtttgcc aagcggttaa gtacgctcga tctcaacgaa atcaacgcgg cggatcgcat
    31681 ggcacagacg ccaaatagat taaaacacgg tcatgttgat gacgatgcgc tgacctttgc
    31741 catctttacc cac
//
LOCUS       DACAOP010000049        31422 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.049, whole genome shotgun sequence.
ACCESSION   DACAOP010000049 DACAOP010000000
VERSION     DACAOP010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31422
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.049"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..567
                     /locus_tag="IT892_002519"
     CDS             <1..567
                     /locus_tag="IT892_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP3135724.1"
                     /translation="IDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKE
                     TQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESE
                     VYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHP
                     IAMDDGLRFAIREGGRTVGAGVVAKVLS"
     gene            797..1180
                     /gene="secE"
                     /locus_tag="IT892_002520"
     CDS             797..1180
                     /gene="secE"
                     /locus_tag="IT892_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007665874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAP3135725.1"
                     /translation="MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLR
                     ALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTA
                     VMSLILWGLDGILVRLVSFITGLRF"
     gene            1182..1727
                     /gene="nusG"
                     /locus_tag="IT892_002521"
     CDS             1182..1727
                     /gene="nusG"
                     /locus_tag="IT892_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005280494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAP3135726.1"
                     /translation="MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEDLFGEVMV
                     PTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAP
                     ISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
                     SVSIFGRATPVELDFSQVEKA"
     gene            1886..2314
                     /gene="rplK"
                     /locus_tag="IT892_002522"
     CDS             1886..2314
                     /gene="rplK"
                     /locus_tag="IT892_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006121495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAP3135727.1"
                     /translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
                     KTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKIS
                     RAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED"
     gene            2318..3022
                     /gene="rplA"
                     /locus_tag="IT892_002523"
     CDS             2318..3022
                     /gene="rplA"
                     /locus_tag="IT892_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAP3135728.1"
                     /translation="MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDV
                     AVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAD
                     QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     VRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTM
                     GAGVAVDQAGLSASVN"
     gene            3435..3932
                     /gene="rplJ"
                     /locus_tag="IT892_002524"
     CDS             3435..3932
                     /gene="rplJ"
                     /locus_tag="IT892_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAP3135729.1"
                     /translation="MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKA
                     GREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKA
                     NAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
                     AKEAA"
     gene            3999..4364
                     /gene="rplL"
                     /locus_tag="IT892_002525"
     CDS             3999..4364
                     /gene="rplL"
                     /locus_tag="IT892_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAP3135730.1"
                     /translation="MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAG
                     PVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKD
                     DAEALKKALEEAGAEVEVK"
     gene            4684..8712
                     /gene="rpoB"
                     /locus_tag="IT892_002526"
     CDS             4684..8712
                     /gene="rpoB"
                     /locus_tag="IT892_002526"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP3135731.1"
                     /translation="MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPE
                     GQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRL
                     VIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
                     KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTE
                     QILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQ
                     LEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIE
                     TLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSE
                     DRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGN
                     RRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGS
                     SQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
                     PNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLD
                     EEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
                     ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDE
                     MYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQ
                     NMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPN
                     VGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVK
                     DSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLF
                     SRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
                     AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYD
                     ENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQ
                     RAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDL
                     PTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
                     AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
                     ESFNVLLKEIRSLGINIELEDE"
     gene            8789..13012
                     /gene="rpoC"
                     /locus_tag="IT892_002527"
     CDS             8789..13012
                     /gene="rpoC"
                     /locus_tag="IT892_002527"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAP3135732.1"
                     /translation="MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETI
                     NYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERM
                     GHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
                     TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLT
                     KRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRN
                     NRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK
                     QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLAT
                     TIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLH
                     PLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVL
                     GLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAK
                     TSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQI
                     MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKV
                     IDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQL
                     AGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
                     RLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADI
                     LVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEA
                     IGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGK
                     LVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITE
                     VSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDV
                     LIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFE
                     ARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERV
                     ERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
                     KATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFI
                     SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEA
                     PAAPQVTAEDASASLAELLNAGLGGSDNE"
     gene            13225..13764
                     /locus_tag="IT892_002528"
     CDS             13225..13764
                     /locus_tag="IT892_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-shock protein C"
                     /protein_id="HAP3135733.1"
                     /translation="MKQEVEKWRPFGHPDGDIRDLSFLDAHQAVYVQHHEGKEPLEYR
                     FWVTYSLHCFTKDYEHQTNEEKQSLMYHAPKESRPFCQHRYNLARTHLKRTILALPES
                     NVIHAGYGSYAVIEVDLDGGDKAFYFVAFRAFREKKKLRLHVTSAYPISEKQKGKSVK
                     FFTIAYNLLRNKQLPQPSK"
     gene            complement(14174..15307)
                     /gene="thiH"
                     /locus_tag="IT892_002529"
     CDS             complement(14174..15307)
                     /gene="thiH"
                     /locus_tag="IT892_002529"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HAP3135734.1"
                     /translation="MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMA
                     LLSPAASGYLEQLAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKR
                     KTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQ
                     PLAETEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQDFFWRLETPDRLGRAGID
                     KIGLGALIGLSDNWRVDSYMVAEHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMD
                     ERQLVQTICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSAFSKTQPGGYADNHP
                     ELEQFSPHDDRRPEAVAAALTAQGLQPVWKDWDSYLGRASQRL"
     gene            complement(15304..16074)
                     /gene="thiG"
                     /locus_tag="IT892_002530"
     CDS             complement(15304..16074)
                     /gene="thiG"
                     /locus_tag="IT892_002530"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418418.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HAP3135735.1"
                     /translation="MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKR
                     VDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDA
                     RWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
                     LETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAK
                     AFRLAVEAGLLARQSGPGSRSYFAHATSPLTGFLEASA"
     gene            complement(16076..16276)
                     /gene="thiS"
                     /locus_tag="IT892_002531"
     CDS             complement(16076..16276)
                     /gene="thiS"
                     /locus_tag="IT892_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HAP3135736.1"
                     /translation="MQILFNDQAMQCAAGQTVHELLEQLDQRQAGAALAINQQIVPRE
                     QWAQHIVQDGDQILLFQVIAGG"
     gene            complement(16260..17015)
                     /gene="thiF"
                     /locus_tag="IT892_002532"
     CDS             complement(16260..17015)
                     /gene="thiF"
                     /locus_tag="IT892_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418420.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole biosynthesis adenylyltransferase ThiF"
                     /protein_id="HAP3135737.1"
                     /translation="MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAA
                     LYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIQLTA
                     LQQRLTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMV
                     LTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGE
                     LRLFDGKSSQWRSLALRRASGCPVCGGSNADPV"
     gene            complement(17008..17643)
                     /gene="thiE"
                     /locus_tag="IT892_002533"
     CDS             complement(17008..17643)
                     /gene="thiE"
                     /locus_tag="IT892_002533"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HAP3135738.1"
                     /translation="MYQPDFPPVPFRSGLYPVVDSVQWIERLLDAGVRTLQLRIKDRR
                     DEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAG
                     LRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYP
                     TVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE"
     gene            complement(17643..19538)
                     /gene="thiC"
                     /locus_tag="IT892_002534"
     CDS             complement(17643..19538)
                     /gene="thiC"
                     /locus_tag="IT892_002534"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HAP3135739.1"
                     /translation="MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRV
                     PMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWID
                     ARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITP
                     EMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANI
                     NHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYI
                     HETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHA
                     GVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSL
                     GDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEE
                     LEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKE
                     DVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYH
                     DETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEI
                     YLRKEEA"
     regulatory      complement(19619..19719)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(19771..20247)
                     /gene="rsd"
                     /locus_tag="IT892_002535"
     CDS             complement(19771..20247)
                     /gene="rsd"
                     /locus_tag="IT892_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma D regulator"
                     /protein_id="HAP3135740.1"
                     /translation="MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKE
                     SYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQ
                     IMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA"
     gene            20342..21115
                     /gene="nudC"
                     /locus_tag="IT892_002536"
     CDS             20342..21115
                     /gene="nudC"
                     /locus_tag="IT892_002536"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HAP3135741.1"
                     /translation="MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRAL
                     QIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCG
                     HEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGF
                     VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPK
                     ELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE"
     gene            21155..22219
                     /gene="hemE"
                     /locus_tag="IT892_002537"
     CDS             21155..22219
                     /gene="hemE"
                     /locus_tag="IT892_002537"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HAP3135742.1"
                     /translation="MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAG
                     DFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSP
                     VTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
                     SKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRD
                     YQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIA
                     DARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVP
                     PEHAGVFVEAVHRLSEQYHR"
     gene            22229..22900
                     /gene="nfi"
                     /locus_tag="IT892_002538"
     CDS             22229..22900
                     /gene="nfi"
                     /locus_tag="IT892_002538"
                     /EC_number="3.1.21.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease V"
                     /protein_id="HAP3135743.1"
                     /translation="MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEV
                     TRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFV
                     DGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLA
                     WVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRY
                     TANQP"
     gene            22943..23533
                     /locus_tag="IT892_002539"
     CDS             22943..23533
                     /locus_tag="IT892_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjaG family protein"
                     /protein_id="HAP3135744.1"
                     /translation="MLQNPIHLRLERLESWQHVTFMACLCERMYPNYAMFCQQTGFGD
                     GQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPSADDFDLYGVYPAIDACVALSE
                     LVHSRLSGETLEHAVEVSKTSITTVAMLEMTQAGREMSDEELKENPAVEQEWDIQWEI
                     FRLLAECEERDIELIKGLRADLREAGESNIGIIFQQ"
     gene            23720..23992
                     /gene="hupA"
                     /locus_tag="IT892_002540"
     CDS             23720..23992
                     /gene="hupA"
                     /locus_tag="IT892_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-alpha"
                     /protein_id="HAP3135745.1"
                     /translation="MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQL
                     VGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK"
     gene            24005..24700
                     /locus_tag="IT892_002541"
     CDS             24005..24700
                     /locus_tag="IT892_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1481 domain-containing protein"
                     /protein_id="HAP3135746.1"
                     /translation="MNSFNEGVVSPLLSFWRRSLMLAGALLLTACSHNSSLPPFTASG
                     FAEDQGAVRIWRKDSGDNVHLLAVFSPWRSGDTTTREYRWQGDNLTLININVYSKPPV
                     NIRARFDDRGDLSFMQRESDGEKQQLSNDQIDLYRYRADQIRQISDALRQGRVVLRQG
                     RWHAMEQTVTTCEGQTIKPDLDSQAIAHIERRQSRSSVDVSVAWLEAPEGSQLLLVAN
                     SDFCRWQPNEKTF"
     gene            complement(24702..25127)
                     /gene="zraP"
                     /locus_tag="IT892_002542"
     CDS             complement(24702..25127)
                     /gene="zraP"
                     /locus_tag="IT892_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc resistance sensor/chaperone ZraP"
                     /protein_id="HAP3135747.1"
                     /translation="MKRNTKIALVMMALSAMAMGSTSAFAHGGHGMWQQNAAPLTSEQ
                     QTAWQKIHNDFYAQSSALQQQLVTKRYEYNALLAANPPDSSKINAVAKEMENLRQSLD
                     ELRVKRDIAMAEAGIPRGAGMGMGYGGCGGGGHMGMGHW"
     gene            25365..26762
                     /gene="zraS"
                     /locus_tag="IT892_002543"
     CDS             25365..26762
                     /gene="zraS"
                     /locus_tag="IT892_002543"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     ZraS"
                     /protein_id="HAP3135748.1"
                     /translation="MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRASEA
                     DRQALLEKGNVLIRALESGSRVGMGMRMHHVQQQALLEEMAGQPGVLWFAVTDAQGII
                     ILHSDPDKVGRALYSPDEMQKLKPEENSRWRLLGKTETTPALEVYRLFQPMSAPWRHG
                     MHNMPRCNGKAVPQVDAQQAIFIAVDASDLVATQSGEKRNTLIILFALATVLLASVLS
                     FFWYRRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPA
                     GGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANS
                     REIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKIS
                     VTDSGKGIAADQLDAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGSTF
                     TLWLPVNITRKDPQG"
     gene            26759..28084
                     /gene="zraR"
                     /locus_tag="IT892_002544"
     CDS             26759..28084
                     /gene="zraR"
                     /locus_tag="IT892_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent response regulator
                     transcription factor ZraR"
                     /protein_id="HAP3135749.1"
                     /translation="MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQ
                     VREQVFDLVLCDVRMAEMDGIATLKEIKALNPAIPVLIMTAYSSVETAVEALKTGALD
                     YLIKPLDFDNLQATLEKALAHTHSIDAETPAVTASQFGMVGKSPAMQHLLSEIALVAP
                     SEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAF
                     TGADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQIISVDVR
                     LIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIPLLAGHFLQRFAERN
                     RKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIASTPIP
                     LGQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR"
     gene            complement(28081..29370)
                     /gene="purD"
                     /locus_tag="IT892_002545"
     CDS             complement(28081..29370)
                     /gene="purD"
                     /locus_tag="IT892_002545"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAP3135750.1"
                     /translation="MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQ
                     NVAIGVTDIPALLDFAQNEKIDLTIVGPEAPLVKGVVDTFRAAGLKIFGPTAGAAQLE
                     GSKAFTKDFLARHKIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
                     LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV
                     GDKDTGPNTGGMGAYSPAPVVTDDVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMI
                     DKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACESKLDEKTSEWDERASLGV
                     VMAAGGYPGDYRTGDVIHGLPLEEVAGGKVFHAGTKLADDEQVVTNGGRVLCVTALGH
                     TVAEAQKRAYALMTDIHWDDCFCRKDIGWRAIEREQN"
     gene            complement(29382..30971)
                     /gene="purH"
                     /locus_tag="IT892_002546"
     CDS             complement(29382..30971)
                     /gene="purH"
                     /locus_tag="IT892_002546"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAP3135751.1"
                     /translation="MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLL
                     AEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVV
                     VNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEM
                     DDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNL
                     NFIKKLDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVK
                     EFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAI
                     ISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRD
                     LGMVGAEELRVVTKRQPSEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSR
                     VYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEV
                     IAAADEHGIAMLFTDMRHFRH"
BASE COUNT         7416 a         8135 c         8594 g         7277 t
ORIGIN      
        1 attgacaagc cgttcctgct gccgatcgaa gacgtattct ccatctccgg tcgtggtacc
       61 gttgttaccg gtcgtgtaga acgcggtatc atcaaagttg gtgaagaagt tgaaatcgtt
      121 ggtatcaaag agactcagaa gtctacctgt actggcgttg aaatgttccg caaactgctg
      181 gacgaaggcc gtgctggtga gaacgtaggt gttctgctgc gtggtatcaa acgtgaagaa
      241 atcgaacgtg gtcaggtact ggctaagccg ggcaccatca agccgcacac caagttcgaa
      301 tctgaagtgt acattctgtc caaagatgaa ggcggccgtc atactccgtt cttcaaaggc
      361 taccgtccgc agttctactt ccgtactact gacgtgactg gtaccatcga actgccggaa
      421 ggcgtagaga tggtaatgcc gggcgacaac atcaaaatgg ttgttaccct gatccacccg
      481 atcgcgatgg acgacggtct gcgtttcgca atccgtgaag gcggccgtac cgttggcgcg
      541 ggcgttgtag caaaagttct gagctaattg ccgataacat ttgacgcaat gcgcactaaa
      601 agggcatcat ttgatgccct ttttgcacgc tttcgtacca gaacctggct catcagtgat
      661 tttctttgtc ataatcattg ctgagacagg ctctgttgag ggcgtataat ccgaaaagct
      721 aatacgcgtt tcgatttggt ttgcctcgcg atcgcggggt gaaaatgttt gtagaaaact
      781 tctgacaggt tggtttatga gtgcgaatac cgaagctcaa ggaagcgggc gcggcctgga
      841 agcgatgaag tgggtcgttg tggtggcatt gctcctggtg gcgattgtcg gcaactatct
      901 ttatcgcgac attatgctgc cgctgcgtgc gctggccgta gtaattctga ttgctgcagc
      961 gggtggtgtc gcgctgttaa cgacaaaagg taaagctacc gttgcttttg cccgtgaagc
     1021 gcgtaccgaa gtccgtaagg tcatttggcc gactcgccag gaaacattgc acaccacgct
     1081 gattgtggct gcggttaccg cagtaatgtc actgatcctg tggggactgg atggtattct
     1141 ggttcgcctg gtatccttta tcactggcct gaggttctga gatgtctgaa gctcctaaaa
     1201 agcgctggta cgtcgttcag gcgttttccg gttttgaagg ccgcgtagca acgtcgctgc
     1261 gtgagcatat caaattacac aacatggaag atttgtttgg tgaagtcatg gtaccaaccg
     1321 aagaagtggt tgaaatccgt ggcggtcagc gtcgcaaaag cgaacgtaaa ttcttccctg
     1381 gctacgtcct cgttcagatg gtgatgaacg acgcgagctg gcacctggtg cgcagcgtac
     1441 cgcgtgtgat gggcttcatc ggcggtactt ccgatcgtcc tgcgccaatc agcgataaag
     1501 aagtcgatgc gattatgaac cgcctgcagc aggttggtga taagccgcgt ccgaaaacgc
     1561 tgtttgaacc gggtgaaatg gtccgtgtta atgatggtcc gttcgctgac ttcaacggtg
     1621 ttgttgaaga agtggattac gagaaatctc gtctgaaagt gtctgtttct atcttcggtc
     1681 gtgcgacccc ggtagagctg gacttcagcc aggttgaaaa agcctaaccc agcgatcaaa
     1741 aaagcggcga tttaatcgtt gcacaaggcg tgagattgga atacaatttc gcgccttttg
     1801 tttttatggg ccttgcccgt aaaacgattt tttatatcac ggggagcctc tcagaggcgt
     1861 tattacccaa cttgaggaat ttataatggc taagaaagta caagcctatg tcaagctgca
     1921 ggttgcagct ggtatggcta acccgagtcc gccagtaggt ccggctctgg gtcagcaggg
     1981 cgtaaacatc atggaattct gcaaagcgtt caacgcaaaa actgattcca tcgaaaaagg
     2041 tctgccgatt ccggtagtaa tcaccgttta cgctgaccgt tctttcactt tcgttaccaa
     2101 gaccccgccg gcagcagttc tgctgaaaaa agcggctggt atcaagtctg gttccggtaa
     2161 gccgaacaaa gacaaagtgg gtaaaatttc ccgcgctcag ctgcaggaaa tcgcgcagac
     2221 caaagctgcc gacatgactg gtgccgacat tgaagcgatg actcgctcca tcgaaggtac
     2281 tgcacgttcc atgggcctgg tagtggagga ctaagaaatg gctaaactga ccaagcgcat
     2341 gcgtgttatc cgcgagaaag ttgatgcaac caaacagtac gacatcaacg aagctatcgc
     2401 actgctgaaa gagctggcga ctgctaaatt cgtagaaagc gtggacgtag ctgttaacct
     2461 cggcatcgac gctcgtaaat ctgaccagaa cgtacgtggt gcaactgtac tgccgcacgg
     2521 tactggccgt tccgttcgcg tagccgtatt tacccaaggt gcaaacgctg aagctgctaa
     2581 agctgcaggc gcagaactgg taggtatgga agatctggct gaccagatca agaaaggcga
     2641 aatgaacttt gacgttgtta ttgcttctcc ggatgcaatg cgcgttgttg gccagctggg
     2701 ccaggttctg ggtccgcgcg gcctgatgcc aaacccgaaa gtgggtactg taacaccgaa
     2761 cgttgctgaa gcggttaaaa acgctaaagc tggccaggtt cgttaccgta acgacaaaaa
     2821 cggcatcatc cacaccacca tcggtaaagt ggactttgac gctgacaaac tgaaagaaaa
     2881 cctggaagct ctgctggttg cgctgaaaaa agcaaaaccg actcaggcga aaggcgtgta
     2941 catcaagaaa gttagcatct ccaccaccat gggtgcaggt gttgcagttg accaggctgg
     3001 cctgagcgct tctgtaaact aatgccttta cgtgggcggt gattttgtct acaatcttac
     3061 ccccacgtat aatgcttaat gcagacgtat atccgagata ttcgggttgt ggcaaggcgg
     3121 caactgagtg agtcgccagg agcatagcta actatgtgac tggtgcgaat gaaggaagcc
     3181 aacgccgtca caagctgaat agcgacggat agaaaagatt tgttcgttgg agcctggcct
     3241 atccaggcct ccgtcgaaga ccgcaggagt ttcgcaagaa acttaatccc ctgcgtagac
     3301 ggtgacagaa cgctaagatt attcttttat attctggctt gtttctgctc accgtaatta
     3361 agacgctctc tccgtttgga ggagtgaagt gagttccaga gattttctct ggcaaacatc
     3421 caggagcaaa gctaatggct ttaaatcttc aagacaaaca agcgattgtt gctgaagtca
     3481 gcgaagtagc caaaggcgcg ctgtctgcag tagttgcgga ttcccgtggc gtaactgtag
     3541 ataaaatgac tgaactgcgt aaagcaggtc gcgaagctgg cgtatacatg cgtgttgttc
     3601 gtaacaccct gctgcgccgt gctgttgaag gtactccgtt cgagtgcctg aaagacgcgt
     3661 ttgttggtcc gaccctgatt gcatactcta tggaacaccc gggcgctgct gctcgtctgt
     3721 tcaaagagtt cgcgaaagcg aatgcaaaat ttgaggtcaa agccgctgcc tttgaaggtg
     3781 agctgatccc ggcgtctcag atcgaccgcc tggcaactct gccgacctac gaagaagcaa
     3841 ttgcacgcct gatggcaacc atgaaagaag cttcggctgg caaactggtt cgtactctgg
     3901 ctgctgtacg cgatgcgaaa gaagctgctt aatcgcagtt atctttttaa cgcattcgct
     3961 tacgtataaa cttattctga tattcaggaa caatttaaat gtctatcact aaagatcaaa
     4021 tcattgaagc agttgcagct atgtctgtaa tggacgttgt agaactgatc tctgcaatgg
     4081 aagaaaaatt cggtgtttcc gctgctgctg ctgtagctgt agctgctggc ccggttgaag
     4141 ctgctgaaga aaaaactgaa ttcgacgtaa ttctgaaagc tgctggcgct aacaaagttg
     4201 ctgttatcaa agcagtacgt ggcgcaactg gcctgggtct gaaagaagct aaagacctgg
     4261 tagaatctgc accggctgct ctgaaagaag gcgtgagcaa agacgacgca gaagcactga
     4321 aaaaagctct ggaagaagct ggcgctgaag ttgaagttaa ataagccaac ccttccggtt
     4381 gcagcctgag aaatcaggct gatggctggt gactttttag tcaccagcct ttttgcgctg
     4441 taaggcgcca gtagcgtttc acactgtttg actactgctg tgcctttcaa tgcttgtttc
     4501 tatcgacgac ttaatatact gcgacaggac gtccgttctg tgtaaatcgc aatgaaatgg
     4561 tttaagcgtg atagcaacag gcattgcgga aagtgttcca ttttccggtc aacaaaatag
     4621 tgttgcacaa actgtccgct caatggacag atgggtcgac ttgtcagcga gctgaggaac
     4681 cctatggttt actcctatac cgagaaaaaa cgtattcgta aggattttgg taaacgtcca
     4741 caagttctgg atgtacctta tctcctttct atccagcttg actcgtttca gaaatttatc
     4801 gagcaagatc ctgaagggca gtatggtctg gaagctgctt tccgttccgt attcccgatt
     4861 cagagctaca gcggtaattc cgagctgcaa tacgtcagct accgccttgg cgaaccggtg
     4921 tttgacgtcc aggaatgtca aatccgtggc gtgacctatt ccgcaccgct gcgcgttaaa
     4981 ctgcgtctgg tgatctatga gcgcgaagcg ccggaaggca ccgtaaaaga cattaaagaa
     5041 caagaagtct acatgggcga aattccgctc atgacagaca acggtacctt tgttatcaac
     5101 ggtactgagc gtgttatcgt ttcccagctg caccgtagtc cgggcgtctt ctttgactcc
     5161 gacaaaggta aaacccactc ttcgggtaaa gtgctgtata acgcgcgtat catcccttac
     5221 cgtggttcct ggctggactt cgaattcgat ccgaaggaca acctgttcgt acgtatcgac
     5281 cgtcgccgta aactgcctgc gaccatcatt ctgcgcgccc tgaactacac cacagagcag
     5341 atcctcgacc tgttctttga aaaagttatc tttgaaatcc gtgataacaa gctgcagatg
     5401 gaactggtgc cggaacgcct gcgtggtgaa accgcatctt ttgacatcga agctaacggt
     5461 aaagtgtacg tagaaaaagg ccgccgtatc actgcgcgcc acattcgcca gctggaaaaa
     5521 gacgacgtca aactgatcga agtcccggtt gagtacatcg caggtaaagt ggttgctaaa
     5581 gactatattg atgagtctac cggcgagctg atctgcgcag cgaacatgga gctgagcctg
     5641 gatctgctgg ctaagctgag ccagtctggt cacaagcgta tcgaaacgct gttcaccaac
     5701 gatctggatc acggcccata tatctctgaa accttacgtg tcgacccaac taacgaccgt
     5761 ctgagcgcac tggtagaaat ctaccgcatg atgcgccctg gcgagccgcc gactcgtgaa
     5821 gcagctgaaa gcctgttcga gaacctgttc ttctccgaag accgttatga cttgtctgcg
     5881 gttggtcgta tgaagttcaa ccgttctctg ctgcgcgaag aaatcgaagg ttccggtatc
     5941 ctgagcaaag acgacatcat tgatgttatg aaaaagctca tcgatatccg taacggtaaa
     6001 ggcgaagtcg atgatatcga ccacctcggc aaccgtcgta tccgttccgt tggcgaaatg
     6061 gcggaaaacc agttccgcgt tggcctggta cgtgtagagc gtgcggtgaa agagcgtctg
     6121 tctctgggcg atctggatac cctgatgcca caggatatga tcaacgccaa gccgatttcc
     6181 gcagcagtga aagagttctt cggttccagc cagctgtctc agtttatgga ccagaacaac
     6241 ccgctgtctg agattacgca caaacgtcgt atctccgcac tcggcccagg cggtctgacc
     6301 cgtgaacgtg caggcttcga agttcgagac gtacacccga ctcactacgg tcgcgtatgt
     6361 ccaatcgaaa cccctgaagg tccgaacatc ggtctgatca actctctgtc cgtgtacgca
     6421 cagactaacg aatacggctt ccttgagact ccgtatcgta aagtgaccga cggtgttgta
     6481 actgacgaaa ttcactacct gtctgctatc gaagaaggca actacgttat cgcccaggcg
     6541 aactccaact tggatgaaga aggccacttc gtagaagacc tggtaacttg ccgtagcaaa
     6601 ggcgaatcca gcttgttcag ccgcgaccag gttgactaca tggacgtatc cacccagcag
     6661 gtggtatccg tcggtgcgtc cctgatcccg ttcctggaac acgatgacgc caaccgtgca
     6721 ttgatgggtg cgaacatgca acgtcaggcc gttccgactc tgcgcgctga taagccgctg
     6781 gttggtactg gtatggaacg tgctgttgcc gttgactccg gtgtaactgc ggtagctaaa
     6841 cgtggtggtg tcgttcagta cgtggatgct tcccgtatcg ttatcaaagt taacgaagac
     6901 gagatgtatc cgggtgaagc aggtatcgac atctacaacc tgaccaaata cacccgttct
     6961 aaccagaaca cctgtatcaa ccagatgccg tgtgtgtctc tgggtgaacc ggttgaacgt
     7021 ggcgacgtgc tggcagacgg tccgtccacc gacctcggtg aactggcgct tggtcagaac
     7081 atgcgcgtag cgttcatgcc gtggaatggt tacaacttcg aagactccat cctcgtatcc
     7141 gagcgtgttg ttcaggaaga ccgtttcacc accatccaca ttcaggaact ggcgtgtgtg
     7201 tcccgtgaca ccaagctggg tccggaagag atcaccgctg acatcccgaa cgtgggtgaa
     7261 gctgcgctct ccaaactgga tgaatccggt atcgtttaca ttggtgcgga agtgaccggt
     7321 ggcgacattc tggttggtaa ggtaacgccg aaaggtgaaa ctcagctgac cccagaagaa
     7381 aaactgctgc gtgcgatctt cggtgagaaa gcctctgacg ttaaagactc ttctctgcgc
     7441 gtaccaaacg gtgtatccgg tacggttatc gacgttcagg tctttactcg cgatggcgta
     7501 gaaaaagaca aacgtgcgct ggaaatcgaa gaaatgcagc tcaaacaggc gaagaaagac
     7561 ctgtctgaag aactgcagat cctcgaagcg ggtctgttca gccgtatccg tgctgtgctg
     7621 gtagccggtg gcgttgaagc tgagaagctc gacaaactgc cgcgcgatcg ctggctggag
     7681 ctaggcctga cagacgaaga gaaacaaaat cagctggaac agctggctga gcagtatgac
     7741 gaactgaaac acgagttcga gaagaaactc gaagcgaaac gccgcaaaat cacccagggc
     7801 gacgatctgg caccgggcgt gctgaagatt gttaaggtat atctggcggt taaacgccgt
     7861 atccagcctg gtgacaagat ggcaggtcgt cacggtaaca agggtgtaat ttctaagatc
     7921 aacccgatcg aagatatgcc ttacgatgaa aacggtacgc cggtagacat cgtactgaac
     7981 ccgctgggcg taccgtctcg tatgaacatc ggtcagatcc tcgaaaccca cctgggtatg
     8041 gctgcgaaag gtatcggcga caagatcaac gccatgctga aacagcagca agaagtcgcg
     8101 aaactgcgcg aattcatcca gcgtgcgtac gatctgggcg ctgacgttcg tcagaaagtt
     8161 gacctgagta ccttcagcga tgaagaagtt atgcgtctgg ctgaaaacct gcgcaaaggt
     8221 atgccaatcg caacgccggt gttcgacggt gcgaaagaag cagaaattaa agagctgctg
     8281 aaacttggcg acctgccgac ttccggtcag atccgcctgt acgatggtcg cactggtgaa
     8341 cagttcgagc gtccggtaac cgttggttac atgtacatgc tgaaactgaa ccacctggtc
     8401 gacgacaaga tgcacgcgcg ttccaccggt tcttacagcc tggttactca gcagccgctg
     8461 ggtggtaagg cacagttcgg tggtcagcgt ttcggggaga tggaagtgtg ggcgctggaa
     8521 gcatacggcg cagcatacac cctgcaggaa atgctcaccg ttaagtctga tgacgtgaac
     8581 ggtcgtacca agatgtataa aaacatcgtg gacggcaacc atcagatgga gccgggcatg
     8641 ccagaatcct tcaacgtatt gttgaaagag attcgttcgc tgggtatcaa catcgaactg
     8701 gaagacgagt aattctcgct caaacaggtc actgctgtcg ggttaaaacc cggcagcgga
     8761 ttgtgctaac tccgacggga gcaaatccgt gaaagattta ttaaagtttc tgaaagcgca
     8821 gactaaaacc gaagagtttg atgcgatcaa aattgctctg gcttcgccag acatgatccg
     8881 ttcatggtct ttcggtgaag ttaaaaagcc ggaaaccatc aactaccgta cgttcaaacc
     8941 agaacgtgac ggccttttct gcgcccgtat ctttgggccg gtaaaagatt acgagtgcct
     9001 gtgcggtaag tacaagcgcc tgaaacaccg tggcgtcatc tgtgagaagt gcggcgttga
     9061 agtgacccag actaaagtac gccgtgagcg tatgggccac atcgaactgg cttccccgac
     9121 tgcgcacatc tggttcctga aatcgctgcc gtcccgtatc ggtctgctgc tcgatatgcc
     9181 gctgcgcgat atcgaacgcg tactgtactt tgaatcctat gtggttatcg aaggcggtat
     9241 gaccaacctg gaacgtcagc agatcctgac tgaagagcag tatctggacg cgctggaaga
     9301 gttcggtgac gaattcgacg cgaagatggg ggcggaagca atccaggctc tgctgaagag
     9361 catggatctg gagcaagagt gcgaacagct gcgtgaagag ctgaacgaaa ccaactccga
     9421 aaccaagcgt aaaaagctga ccaagcgtat caaactgctg gaagcgttcg ttcagtctgg
     9481 taacaaacca gagtggatga tcctgaccgt tctgccggta ctgccgccag atctgcgtcc
     9541 gctggttccg ctggatggtg gtcgtttcgc gacttctgac ctgaacgatc tgtatcgtcg
     9601 cgtcattaac cgtaacaacc gtctgaaacg tctgctggat ctggctgcgc cggacatcat
     9661 cgtacgtaac gaaaaacgta tgctgcagga agcggtagac gccctgctgg ataacggtcg
     9721 tcgcggtcgt gcgatcaccg gttctaacaa gcgtcctctg aaatctttgg ccgacatgat
     9781 caaaggtaaa cagggtcgtt tccgtcagaa cctgctcggt aagcgtgttg actactccgg
     9841 tcgttctgta atcaccgtag gtccatacct gcgtctgcat cagtgcggtc tgccgaagaa
     9901 aatggcactg gagctgttca aaccgttcat ctacggcaag ctggaactgc gtggtcttgc
     9961 taccaccatt aaagctgcga agaaaatggt tgagcgcgaa gaagctgtcg tttgggatat
    10021 cctggacgaa gttatccgcg aacacccggt actgctgaac cgtgcaccga ctctgcaccg
    10081 tctgggtatc caggcatttg aaccggtact gatcgaaggt aaagctatcc agctgcaccc
    10141 gctggtttgt gcggcatata acgccgactt cgatggtgac cagatggctg ttcacgtacc
    10201 gctgacgctg gaagcccagc tggaagcgcg tgcgctgatg atgtctacca acaacatcct
    10261 gtccccggcg aacggcgaac caatcatcgt tccgtctcag gacgttgtac tgggtctgta
    10321 ctacatgacc cgtgactgtg ttaacgccaa aggcgaaggc atggtgctga ctggcccgaa
    10381 agaagcagaa cgtctgtatc gctctggtct ggcttctctg catgcgcgcg ttaaagtgcg
    10441 tatcaccgag tatgaaaaag atgctaacgg tgaattagta gcgaaaacca gcctgaaaga
    10501 cacgactgtt ggccgtgcca ttctgtggat gattgtaccg aaaggtctgc cttactccat
    10561 cgtcaaccag gcgctgggta aaaaagcaat ctccaaaatg ctgaacacct gctaccgcat
    10621 tctcggtctg aaaccgaccg ttatttttgc ggaccagatc atgtacaccg gcttcgccta
    10681 tgcagcgcgt tctggtgcat ctgttggtat cgatgacatg gtcatcccgg agaagaaaca
    10741 cgaaatcatc tccgaggcag aagcagaagt tgctgaaatt caggagcagt tccagtctgg
    10801 tctggtaact gcgggcgaac gctacaacaa agttatcgat atctgggctg cggcgaacga
    10861 tcgtgtatcc aaagcgatga tggataacct gcaaactgaa accgtgatta accgtgacgg
    10921 tcaggaagag aagcaggttt ccttcaacag catctacatg atggccgact ccggtgcgcg
    10981 tggttctgcg gcacagattc gtcagcttgc tggtatgcgt ggtctgatgg cgaagccgga
    11041 tggctccatc atcgaaacgc caatcaccgc gaacttccgt gaaggtctga acgtactcca
    11101 gtacttcatc tccacccacg gtgctcgtaa aggtctggcg gataccgcac tgaaaactgc
    11161 gaactccggt tacctgactc gtcgtctggt tgacgtggcg caggacctgg tggttaccga
    11221 agacgattgt ggtacccatg aaggtatcat gatgactccg gttatcgagg gtggtgacgt
    11281 taaagagccg ctgcgcgatc gcgtactggg tcgtgtaact gctgaagacg ttctgaagcc
    11341 gggtactgct gatatcctcg ttccgcgcaa cacgctgctg cacgaacagt ggtgtgacct
    11401 gctggaagag aactctgtcg acgcggttaa agtacgttct gttgtatctt gtgacaccga
    11461 ctttggtgta tgtgcgcact gctacggtcg tgacctggcg cgtggccaca tcatcaacaa
    11521 gggtgaagca atcggtgtta tcgcggcaca gtccatcggt gaaccgggta cacagctgac
    11581 catgcgtacg ttccacatcg gtggtgcggc atctcgtgcg gctgctgaat ccagcatcca
    11641 agtgaaaaac aaaggtagca tcaagctcag caacgtgaag tcggttgtga actccagcgg
    11701 taaactggtt atcacttccc gtaatactga actgaaactg atcgacgaat tcggtcgtac
    11761 taaagaaagc tacaaagtac cttacggtgc ggtactggcg aaaggcgatg gcgaacaggt
    11821 tgctggcggc gaaaccgttg caaactggga cccgcacacc atgccggtta tcaccgaagt
    11881 aagcggtttt gtacgcttta ctgacatgat cgacggccag accattacgc gtcagaccga
    11941 cgaactgacc ggtctgtctt cgctggtggt tctggattcc gcagaacgta ccgcaggtgg
    12001 taaagatctg cgtccggcac tgaaaatcgt tgatgctcag ggtaacgacg ttctgatccc
    12061 aggtaccgat atgccagcgc agtacttcct gccgggtaaa gcgattgttc agctggaaga
    12121 tggcgtacag atcagctctg gtgacaccct ggcgcgtatt ccgcaggaat ccggcggtac
    12181 caaggacatc accggtggtc tgccgcgcgt tgcggacctg ttcgaagcac gtcgtccgaa
    12241 agagccggca atcctggctg aaatcagcgg tatcgtttcc ttcggtaaag aaaccaaagg
    12301 taaacgtcgt ctggttatca ccccggtaga cggtagcgat ccgtacgaag agatgattcc
    12361 gaaatggcgt cagctcaacg tgttcgaagg tgaacgtgta gaacgtggtg acgtaatttc
    12421 cgacggtccg gaagcgccgc acgacattct gcgtctgcgt ggtgttcatg ctgttactcg
    12481 ttacatcgtt aacgaagtac aggacgtata ccgtctgcag ggcgttaaga ttaacgataa
    12541 acacatcgaa gttatcgttc gtcagatgct gcgtaaagct accatcgtta acgcgggtag
    12601 ctccgacttc ctggaaggcg aacaggttga atactctcgc gtcaagatcg caaaccgcga
    12661 actggaagcg aacggcaaag tgggtgcaac ttactcccgc gatctgctgg gtatcaccaa
    12721 agcgtctctg gcaaccgagt ccttcatctc cgcggcatcg ttccaggaga ccactcgcgt
    12781 gctgaccgaa gcagccgttg cgggcaaacg cgacgaactg cgcggcctga aagagaacgt
    12841 tatcgtgggt cgtctgatcc cggcaggtac cggttacgcg taccaccagg atcgtatgcg
    12901 tcgccgtgct gcgggtgaag ctccggctgc accgcaggtg actgcagaag acgcatctgc
    12961 cagcctggca gaactgctga acgcaggtct gggcggttct gataacgagt aatcgttaat
    13021 ccgcaaataa cgtaaaaacc cgcttcggcg ggttttttta tggggggagt ttagggaaag
    13081 agcatttgtc agaatattta aggaatttct gaatactcat aatcaatgta gagatgacta
    13141 atatcctgaa actgactgaa ctaattgagt caaactcggc aaggattcga tactattcct
    13201 gtgtaacttt cttaaggaac gagaatgaaa caggaagtgg aaaagtggcg accttttgga
    13261 catccggatg gtgatattcg tgatttatca tttcttgatg ctcatcaggc tgtctacgtt
    13321 cagcatcatg agggcaaaga gcctttagag tatcgctttt gggttaccta ctctcttcac
    13381 tgcttcacaa aagattatga acatcagacg aacgaagaaa aacaatcgtt aatgtaccac
    13441 gcgcctaaag aatctcgtcc cttctgccag caccgttata acttagcgcg cacacactta
    13501 aaaagaacta ttttggcgct gccagaaagc aacgttattc atgccgggta tggtagctat
    13561 gccgtgattg aggtggactt agacggagga gataaggcat tttactttgt tgcgttcagg
    13621 gctttcaggg aaaagaaaaa actccgtttg catgtaacta gcgcttatcc catttctgaa
    13681 aaacagaaag gtaaatcagt gaaatttttc accattgcct acaacttatt gagaaataag
    13741 cagcttcctc agccctcaaa ataacaaaac ccaccttaag gtgggtttcg ccagagaatt
    13801 atctctggta ttcagaacgc cattaccgga ctttgccttg accttgcgat aatcgcaggt
    13861 tgcgggatgt ctgaatttct tcagtctgct gcatcctgga agatgagaac atgtgttctt
    13921 attttcgtct ctatcatagt tgagtattta ctctcttaca atcagatctc tttcattgct
    13981 caacaggcga tggcttcaga ctttgcatta cggaattttt aagaaaggca gggcgaaacg
    14041 aggaagaagc ttttcgccct ggacaacatt cctgctgacg gcactaccat aaaaaaacac
    14101 aacgctttca acaaccttgc gtttttcatc ttccgtagcg gctcggaata aatttacgtt
    14161 cttacattcc gtctcatagt ctttgcgagg cgcgtcccag atagctgtcc cagtctttcc
    14221 ataccggctg caaaccctga gcggttaacg cggcagcaac cgcttccggt ctgcgatcgt
    14281 cgtgcggtga gaactgttcc aactcggggt gattatcggc atagccacct ggctgcgttt
    14341 tcgagaaggc gctgacgtta ttgatcgcca gcggaataac gcgatcgcga aaccacggtg
    14401 attcccgcgt ggagagtgac agttcaatct ccggtgcaag cagtcgaaag gcgcagatgg
    14461 tttgcactaa ctggcgttca tccataatcg acgcaggctc aatgccgcca gtacacgggc
    14521 gcaggcgcgg aaaggagaca gagtaacggc tttgccagta atgctgttgc agccatagca
    14581 aatgttcggc aaccatatag ctgtcaacgc gccagttgtc ggaaaggcca attagcgcgc
    14641 cgaggcctat cttatcaatc cccgcacgcc ccagccgatc cggcgtttcc agccgccaga
    14701 agaagtcctg ttttttgcct ttcagatgat ggcgggcata agtcgcctcg tgatatgtct
    14761 cctgataaac catcacgcca tccagaccaa gttgctttaa ctcggcgtat tccgtctccg
    14821 ccagcggttg cacttccatc tgtagtgaag agaactgttc acgaagggca gggagatgac
    14881 gacgaaagta atccatcccc actttcgcct gatgttcacc agtgactaac agcagatgtt
    14941 caaagcccat ctcccgtata gcggcacttt ccctagcaat atccgcttca tccagcgttt
    15001 tgcgcttgat gcgattactc atggaaaatc cacagtacgt gcagtcgtta gcgcaaagat
    15061 tggaaagata aagcgggacg tagaaactaa ctgtgttgcc aaatcgctga cgggtcagac
    15121 gctgcgcccg ttgggccagt tgttccagat agccactggc ggcaggcgat aacagcgcca
    15181 tcatgtcgtc gcgggtgagt tgcgaggcat ttagcgcccg ctctacgtca gcagccgttt
    15241 tgccgttgat acgcaggcgg atgtcgtccc agtccagttg tcgccagcga tcgctgaagg
    15301 ttttcatgcc gatgcctcca gaaatccggt cagcgggctg gtggcatgag caaaataact
    15361 gcggctgccc ggtccggact gacgtgccag taggcctgct tctaccgcca gacgaaatgc
    15421 cttcgccatg ttgacgggat cgtccgcgac ggcaatcgcc gtattcacta acaccgcgtc
    15481 ggcccccatt tccagcgcct gcgcggcatg gctgggaacg ccgatgccag catcgacaac
    15541 caccggcact gtggcctgct ggataataat ctccagcatg gcgcgggttt ccagtccctg
    15601 attcgagcca atcggcgcgc cgagcggcat caccgctgca cagccgactt cttccagacg
    15661 tttacacaat accggatcgg ccccgcagta aggcagcacg acaaatccct gttgtaccag
    15721 cgtttcggcg gctttcaggg tttcgatggg atcgggcaac agccagcggg cgtcagggtg
    15781 aatctctaat tttaaccagt ttgtgcctaa cgcttcacga gccagatggg cggcgaaaat
    15841 ggcttcttcc gctgttttcg ccccggatgt atttggcagc agggtcacac ccgccgcgat
    15901 aagcggttcg aggatagcgt cgttgtgctg gcgcaagtcg acacgtttca tcgccagtgt
    15961 caccagctgg ctgccggaag cgcggatcgc ctccaccatc agttgtgaag aagcgaattt
    16021 ccctgtgccg gtaaacagat gtgaatcaaa cgttttgtcc gcaatacgta acatttcaac
    16081 cccctgcaat aacctgaaaa agcaggatct ggtcgccatc ctgcacgata tgttgcgccc
    16141 actgctcacg cgggacgatt tgctgattaa tcgccagagc cgcgcccgct tgtcgttggt
    16201 cgagttgctc cagtagttcg tgaacagttt gcccggcggc gcactgcatc gcttgatcgt
    16261 taaacaggat ctgcattgct tcctccgcat accgggcaac cactggcgcg gcgcaacgcc
    16321 aggctgcgcc actggctcga tttaccgtcg aacagtcgga gttctcccgc aggtgtctct
    16381 ataccgctta ataacttaat ggcttccagt gcctgcaaag tgcccataac cccgaccacc
    16441 gggccaacca cgcccgccgt gcggcagttg cgttctggct cctggttatc tggccacagg
    16501 cagcggtaac acccctgctc ccagggcggc gtcagtacca tcaactgacc gccaaatccg
    16561 accgcgctgg cggtgataag cggcgtgttg agtgccacgc aggcggcatt aatctcctgg
    16621 cgagtcgcca tattgtcggt acagtcgagc accacatcgg cccgtgcaac cgcatctttt
    16681 aacgcctcac ccgttaaccg ttgttgtaat gctgtcagtt gaatgtcggg attcaactgt
    16741 gtcagtcgct gttggctgac ctgcgatttc gggcgatcga tatcttcagt ggtaaagagg
    16801 atttgtcgtt gcagattgct taaatgcaca tcgtcgtcat ctgccagtac cagcgtcccg
    16861 acgccagcgc ccgccaggta cagcgcagca ggtgtaccca gcccgcccag accgataatc
    16921 agcacctggc tgtcgagcag tttttgctgc ccgtccagag cgatatcgtc gagcaggatt
    16981 tggcggctat aacgcataaa gtcacggtca ttcatcgcca actcctgcaa tttccagcaa
    17041 ctgtgccgtt gccaaacgcc agtctgcggc ttgagtaatg gcgctgacga cggcgatact
    17101 gccgacaccc gttgctatca ccgcaggcgc gcgtgccaga ctgataccgc caatcgccac
    17161 ggtgggataa tccgccagtc gctcaacatg ccgtgccagc tgttccagcc cctgcggtgc
    17221 agaaggcatc tgtttggttt gcgtcgggaa cacatgtccc agcgcgatat aagaggggcg
    17281 tgctgccagc gcgacgtcga tttccatatc gtcatgtgtc gaaacgccca gccgcaggcc
    17341 tgccgcgcgg atggcattga gatcggtggc ttgcaaatct tcctgcccca aatggacgcc
    17401 atacgcctga tgcttgatcg ccagccgcca gtaatcgttg ataaacaatc gcgcgttata
    17461 gcggcggccc agcgcaattg ccgccacgac atcggcttcc acctcttcat cgcgccgatc
    17521 tttgatgcgt agctggagag tacgtacgcc tgcatccaac agacgttcga tccactgtac
    17581 gctgtccacc accgggtaca gtcctgaacg aaaaggtaca ggaggaaaat caggctgata
    17641 catcacgctt cctccttacg caggtagatt tctccgcctc tggcacggaa gttctccgac
    17701 atatccgcca ttcccatttc aatagtttgc gtggcggcgt aatcacgcac ttcctggctg
    17761 attttcatcg agcagaattt cggcccacac atggagcaaa aatgggcgac tttacctgac
    17821 tcttgcggca gggtttcatc gtgataagcg cgggcggtaa acgggtcgag ggccagatta
    17881 aactggtctt cccagcgaaa ttcgaagcgg gctttcgaca tggcgttatc gcgaatttgc
    17941 gcgcccggat gccctttcgc caggtcagcg gcgtgggcgg caatcttata ggtgataagc
    18001 ccctgcttaa catcttcttt attgggcaga cccagatgct cttttggcgt tacgtaacag
    18061 agcatcgcgc agccaaacca gccaatcatc gccgcaccaa tccccgacgt gaagtggtca
    18121 tagcccggcg caatatcggt agttagcggc cccagagtgt aaaacggcgc ttcgtggcag
    18181 tgctctaact cctcggtcat attgcggcgg atcatctgca tcggcacgtg gcctgggcct
    18241 tcaatcatca cctgcacgtc atattcccag gcaattttgg tcagttcgcc cagcgtatgc
    18301 agctcggcaa actgcgcttc atcgttggcg tcctgaatag aaccggggcg cagaccgtcg
    18361 cccagcgaca gcgaaacgtc ataagcggca cagatttcac aaatttcgcg gaagtgttga
    18421 tagaggaaat tttcctgatg atgggagagg caccatttcg ccataatcga accgccgcga
    18481 gagacgatac cggtcaggcg tttcgcggtc atcggcacat agcgcagcag tacgcccgca
    18541 tggatagtga agtaatccac accttgctcg gcctgttcca gcagcgtgtc gcggaacgct
    18601 tcccaggtaa gatcttcggc gatcccgtta accttctcca gcgcctggta gatcggcact
    18661 gtaccgatcg gcaccgggct gttacgcaaa atccactcgc gggtttcgtg aatatagcga
    18721 ccggtggaga gatccatcac cgtatccgct ccccagcgcg tggaccatac cagcttttcc
    18781 acttcttctt cgatggaaga ggtgaccgcc gagttgccga tattggcgtt aacttttacc
    18841 aggaaattgc gaccaataat catcggctcc gattccggat gattaatgtt ggccgggata
    18901 atcgcacgtc cggcagcaac ttcatcacgg acaaattccg cagtgatatt ttccggcaga
    18961 tgtgcgccaa agctcattcc cggatgctgg tggcgtaaaa cctcgctacg gatgcgctcg
    19021 cggcccatat tctcgcggat ggcgatgaat tccatttccg gcgtgatgat gccctggcgg
    19081 gcgtagtgca gttgggtgac acggcgtcct gctttggcgc gttttggtgt tagtacgccg
    19141 ctaaaacgca gttcgtcgag gccatcatct gccagccgcg ctttagtgta atcggaactg
    19201 cgcacggtaa gttcttcggt atcgccgcgc gcatcgatcc acggctggcg tagttttgcc
    19261 agcccttgct gcacgttaat ggcaatctgc ggatcaccat acgggccgga ggtgtcgtag
    19321 accggaatcg cttcgttttc ttcgtactgc ggctgttctt tgctaccgcc aattagcgtc
    19381 gggctaagct ggatctcacg catcggcacg cgcacgccgg ggtgtgtgcc agtgatataa
    19441 atgcgttttg agttgggaaa ggcggtgcct tccagggtgt cgataaaatg ttgggcccgg
    19501 gcgcgttgtt cgcggcgggt cagttttgtt gcagacatag ctcattccaa aaagttaagg
    19561 acgtggcttg tcagacgacg gatgaagcaa gagacgatcg ccgcaggggc gatgcgatag
    19621 cagattaact cttgttccct tcgcaggtat tagcctgatc aggttccgcg gatcccgaat
    19681 aaacggtctc agccagttaa ggcactccga caagaaatta gccccgcaaa tggggcattg
    19741 aatgtaaatt acgcgttaac agcgcagaac tcaagcagga tgtttgacgc gggcggcgtc
    19801 aagcaccagc agaatcagct tatcttccag cacaaagcgc gcttccagcg cctcgccgat
    19861 gtcagataaa acctgttgaa actcaaggta attatcatga tcgatggcgg tttccagact
    19921 ggaatcgtag taatccataa tctgttgagt attggcttcg agttgcggcc aaatcttcgc
    19981 ggcgcgcgcg agttgcccgt tgccttccag cttatgaaga atgcgctcat aaatactgaa
    20041 atgtccggca gacaagtaat cgaccaggct ctgacaaaaa tcatcaaggg ctttttcgtt
    20101 tagcctcatg tacgattctt tgccaggctt aatgccaacc agattgtagt aagccacgag
    20161 cagatgctta cgtacatgta gccagcgatc aaccagtttg ttacttcctc tgacgcgctc
    20221 cgtcaggtta tcgagctggt taagcatgat tgactccgca agtttgtatt caaaaactgc
    20281 tcagtgagaa atgtaaaaac catgttaaac atgccagtga tgcaaaggta gtgcaagagc
    20341 tatggatcgt ataattgaaa aattagatca cggctggtgg gtcgtcagcc atgaacaaaa
    20401 attatggttg ccgaagggag aattgccata tggcgaagcg gcaaatttcg atcttgtggg
    20461 tcagcgcgca ctacaaatcg gcgaatggca gggggaacct gtttggttag tacaacagca
    20521 gcggcgtcac gatatggggt cggtacgtca ggtcattgat ctcgatgttg ggctgtttca
    20581 actggccgga cgaggcgtac aactggcgga gttttaccga tcgcataaat actgtggtta
    20641 ctgcgggcat gaaatgtatc cgagcaaaac cgaatgggcg atgctgtgca gccattgccg
    20701 tgagcgttac tacccgcaaa tcgccccctg cattattgtt gccatccgtc gcgatgattc
    20761 gatcctcctc gcccagcata cccgccatcg taacggtgtc catacagtac ttgccggatt
    20821 cgtcgaagtg ggcgaaaccc tcgagcaggc agtcgcgcgg gaagtgatgg aagagagcgg
    20881 aattaaagtt aaaaacttgc gttacgtgac ttctcagccg tggccgtttc ctcagtcttt
    20941 aatgaccgcg tttatggcgg aatatgacag cggcgacatc gtgatcgacc cgaaagaatt
    21001 gctcgaggcg aactggtatc gctatgacga tttgccgtta ctcccgccgc ccggcaccgt
    21061 agcgcgccgt ctgatagaag atacggtggc gatgtgtcgg gcagagtatg agtgatgata
    21121 cactgaccgc ctgacgcact aaggaacagc caaaatgacc gaacttaaaa acgatcgtta
    21181 tctgcgggcg ctgctgcgcc agcccgttga tgtcactcca gtatggatga tgcgccaggc
    21241 gggtcgctat ctaccggaat ataaagccac gcgcgcccag gcaggcgatt ttatgtcgct
    21301 gtgcaaaaac gccgagctgg cgtgcgaagt gactttgcaa ccgctgcgtc gctacccgct
    21361 ggatgcggcg atcctctttt ccgatatcct caccgtgccg gacgcgatgg ggttagggct
    21421 ctattttgaa gccggagaag gtccgcgttt tacctcgcca gtcacctgca aagctgacgt
    21481 cgataaactg ccaattccgg acccggaaga tgaactgggt tacgtgatga acgcggtgcg
    21541 taccattcgt cgcgaactga aaggcgaagt gccgctgatt ggtttttccg gcagcccgtg
    21601 gacgctggcg acctacatgg tggaaggcgg cagcagcaaa gccttcaccg tgatcaaaaa
    21661 aatgatgtat gccgatccgc aggcgctgca cgctctgctc gataaactgg cgaaaagcgt
    21721 cactttgtat ctgaatgcgc agattaaagc cggtgctcag gcagtgatga ttttcgacac
    21781 ctggggcggc gtgcttaccg ggcgcgatta tcaacagttc tcgctctatt acatgcataa
    21841 aattgttgat ggtttactgc gtgaaaacga cggtcgccgc gtaccggtca cgctgtttac
    21901 caaaggcggc ggacagtggc tggaagccat ggcagaaacc ggttgcgatg cgctgggcct
    21961 cgactggaca acggacatcg ccgatgcgcg ccgccgtgtg ggcaataaag tcgcgttgca
    22021 gggtaatatg gatccgtcga tgctgtacgc gccgcctgcc cgcattgaag aagaagtagc
    22081 gactatactt gcaggtttcg gtcacggcga aggtcatgtc tttaaccttg gtcacggcat
    22141 tcatcaggat gtgccgccag aacatgctgg cgtgttcgtg gaggcagtgc atcgactgtc
    22201 tgaacagtat caccgctaag gagtgattat ggatctcgcg tcattacgcg ctcaacaaat
    22261 cgaactggct tcttctgtga tccgcgagga tcgactcgat aaagatccac cggatctgat
    22321 cgccggagcc gatgtcgggt ttgagcaggg cggagaagtg acgcgagcgg cgatggtgct
    22381 gctgaaatat ccctcgcttg agctggtcga gtataaagtt gcccgcatcg ccaccaccat
    22441 gccttacatt ccaggttttc tttccttccg cgaatatcct gcgctgctgg cagcgtggga
    22501 gatgctgtcg caaaagccgg atttagtgtt tgtcgatggt catgggatct cgcatcctcg
    22561 ccgtcttggc gtcgccagcc attttggctt attggtggat gtgccgacca ttggcgtggc
    22621 gaaaaaacgg ctctgcggta aattcgaacc gctctccagc gaaccgggcg cgctggcccc
    22681 actgatggat aaaggcgagc agctggcctg ggtctggcgc agcaaagcgc gctgtaaccc
    22741 gttgtttatc gctaccggcc atcgggtcag cgtggacagc gcgctggcgt gggtacaacg
    22801 ctgcatgaaa ggctatcgtc tgccggagcc aacgcgctgg gcggacgcgg tggcctcgga
    22861 acgtccggcg ttcgtgcgct atacagcaaa tcagccctaa ttcaggtaaa ctgcggataa
    22921 tttccgtatt tgagaactca acatgttaca aaacccaatt catctgcgtc tggagcgcct
    22981 ggaaagctgg cagcatgtca ctttcatggc ttgcttatgc gaacgcatgt accccaatta
    23041 cgccatgttc tgccagcaaa ccggttttgg tgatgggcaa atttaccgtc gcattctcga
    23101 tctcatctgg gaaacgctga ccgttaaaga cgcaaaagta aatttcgaca gccaactgga
    23161 gaaatttgaa gaagcgattc cttcagccga cgatttcgat ctgtacggcg tttatccggc
    23221 aatcgatgcc tgcgtggcgt taagtgaact ggtccattcg cgtttgagtg gtgaaacgct
    23281 cgaacacgcg gtggaagtga gtaagacctc catcacgacc gttgcgatgc tggaaatgac
    23341 tcaggctggt cgcgaaatga gcgatgaaga gcttaaagaa aacccagctg tagagcaaga
    23401 atgggacatt cagtgggaaa tattccgact tttagctgag tgcgaagaac gcgatatcga
    23461 gctgataaaa ggccttaggg cagacctgcg tgaggcgggt gagagcaata ttggtataat
    23521 ttttcagcaa taagaccaga aaacgtgatt taacgcctga tttgtcgtac ctggagtctt
    23581 ccctttcgcc ccccgtctgg tctacatttg gggggcgaaa aaaagtggct atcggtgcgt
    23641 gtatgcagga gagtgctatt ctggcatttc cgtcgcactc gatgcttagc aagcgataaa
    23701 cacattgtaa ggataactta tgaacaagac tcaactgatt gatgtaattg cagagaaagc
    23761 agaactgtcc aaaacccagg ctaaagctgc tctggagtcc actctggctg caattactga
    23821 gtctctgaaa gaaggcgatg ctgtacaact ggttggtttc ggtaccttca aagtgaacca
    23881 ccgcgctgag cgtactggcc gcaacccgca gaccggtaaa gaaatcaaaa ttgccgcagc
    23941 taacgtaccg gcatttgttt ctggcaaggc actgaaagac gcagttaagt aagattgcgt
    24001 ggcagtgaac agttttaacg aaggggtggt ttcacccctt ttgtctttct ggcgtcgatc
    24061 attgatgctg gctggcgctc tgcttctcac tgcctgtagt cataactctt cacttcctcc
    24121 ctttaccgcc agtggatttg ctgaagacca gggcgcggta cgcatctggc gaaaagacag
    24181 cggcgataat gtgcatctgc ttgccgtgtt tagcccgtgg cgcagtggcg ataccacgac
    24241 gcgagagtat cgctggcagg gcgataacct cacgctcatc aatatcaatg tttacagcaa
    24301 accgccggtg aatattcgcg cgcgttttga cgatcgcggt gatctgagct ttatgcaacg
    24361 tgaatccgat ggggaaaagc agcagctttc taacgaccaa atcgatttat accgttatcg
    24421 tgctgatcag atccgccaga ttagcgatgc cttacgtcag gggagagtcg tgctgcgcca
    24481 ggggcgctgg catgcgatgg aacagaccgt gaccacctgc gaagggcaaa ccattaaacc
    24541 tgatttagat tcgcaggcga tagcgcatat cgagcgccgc cagagccgct cttctgttga
    24601 tgtcagcgtg gcatggctgg aagcgcccga aggttcgcaa ttactgttag tggcaaactc
    24661 tgatttctgt cgctggcaac ccaacgagaa aacgttctga tttaccagtg gcccataccc
    24721 atatgaccgc caccaccgca gccgccgtag cccatgccca ttccggctcc gcgcggaata
    24781 cccgcttcag ccatcgcgat atctcgtttc acccgtaact catctaacga ctgacgcaaa
    24841 ttctccatct ctttggcgac cgcgttaatt ttgctgctat ccggtgggtt cgcggctaac
    24901 agggcattgt attcataacg cttcgtcacc agttgctgtt gcagtgcgct gctttgagcg
    24961 taaaagtcat tatggatttt ctgccacgct gtctgttgtt cgctggtcaa aggcgcggca
    25021 ttttgctgcc acataccgtg tccgccgtga gcaaatgcag atgtcgatcc catcgccatt
    25081 gctgaaagcg ccatcattac cagggcaatt ttcgtgttcc gtttcatggt taatcctcca
    25141 gtggttgtct tacttcgggt attgcatctt ccgtgccaac gatgaaacgc tgatatgacg
    25201 ggtaatctgg catgataaac gagtaaaaat gactcgcctg ctgcgggtag cgagtcattt
    25261 ttactcattg aaacttaagc ctttgtgtta cagcgcaggg taagcgctga taaaagatgg
    25321 catgatttct gctgtcagaa agggatgagc aggcaaagaa gaagatgcgt tttatgcaac
    25381 gttctaaaga ctccttagct aaatggttaa gcgcgatcct ccccgtggtc attgttgggc
    25441 tggtgggatt gtttgcggta actgtgattc gtgattatgg gcgggcaagc gaggcagacc
    25501 gccaggcatt actggaaaaa ggtaatgtgc ttatccgcgc tctggagtcg ggaagccgcg
    25561 tagggatggg gatgcgaatg caccatgtac agcaacaggc gcttctggaa gagatggcgg
    25621 gacagccggg agtgttgtgg ttcgcagtca ccgatgcgca gggcatcatt attcttcata
    25681 gcgaccccga taaggtcggg cgtgcgctct attcgccgga tgaaatgcag aaattaaagc
    25741 cagaggaaaa ctcccgctgg cggctgcttg ggaaaacgga aactacgcct gcacttgagg
    25801 tctatcgttt gttccagcca atgtcagcgc cctggcggca tggaatgcac aatatgccgc
    25861 gctgtaacgg caaagctgtg ccacaagtag atgcacaaca ggctattttt atcgccgttg
    25921 atgccagtga tctggttgca acccagagtg gggaaaagcg caataccctg attatcctct
    25981 tcgccctggc gacggtcttg ctggcaagcg tattgtcatt cttctggtat cgccgctatc
    26041 tgcgctcgcg ccagcttcta caagatgaaa tgaagcgcaa agagaagctg gtggcgctgg
    26101 ggcatcttgc ggcaggcgtt gcccacgaaa tccgtaaccc actttcctcg attaaaggac
    26161 tggcgaaata ctttgccgag cgcgcgcctg cagggggaga agcgcatcaa ctggcgcagg
    26221 tgatggcgaa agaggccgac cgtttaaacc gcgtggtaag cgagttgctg gaactggtta
    26281 agccaacgca tctggctttg caggcggtgg atctcaacac gctgattaac cactcattac
    26341 agctggtaag tcaggatgca aacagccggg agatccagtt acgctttacc gccaacgaca
    26401 cattaccgga aattcaggcc gacccggaca ggctgactca ggtcctgttg aatctctatc
    26461 tcaatgctat tcaggcgatt ggtcagcatg gcgtgattag cgtgacggcc agcgaaagcg
    26521 gcgcgggcgt gaaaatcagc gttaccgaca gcggtaaggg aattgcggca gatcagcttg
    26581 atgccatctt cactccgtac ttcaccacta aagccgaagg caccggattg gggctggcgg
    26641 tcgtgcataa tattgttgaa caacacggtg gtacaattca ggtcgcaagc caggagggaa
    26701 aaggctcaac gttcaccctc tggcttccgg tcaatattac gcgtaaggac ccacaaggat
    26761 gacgcacgat aatatcgata ttctggtggt ggatgatgac attagccact gcactatttt
    26821 gcaggcttta ctgcgcggct ggggctataa cgtcgcgctg gcgaacagcg ggcgacaggc
    26881 gttggagcag gtgcgggaac aggtttttga tcttgtgctt tgcgatgtgc gaatggcgga
    26941 gatggacggc atcgccacgc tgaaagagat caaagcgtta aacccggcaa ttccggtgct
    27001 gattatgact gcgtactcca gcgtcgagac ggcggtagag gcactgaaaa ctggggcgct
    27061 ggattatctc atcaagccgc tggatttcga taacctacag gcgacgctgg aaaaagcgct
    27121 cgcgcatacg cacagtattg atgctgaaac acctgcggtg actgccagcc agttcggtat
    27181 ggtcggtaaa agcccggcga tgcaacacct gctcagtgaa atcgccctcg tcgcgccatc
    27241 ggaagccacg gtactgatcc acggcgattc cggcaccggt aaagagctgg tcgccagggc
    27301 gattcacgcc agtagcgcac gtagcgaaaa accgctggta acgctcaact gtgcggcact
    27361 caacgaatcc ttgctggaat ctgaattgtt cggtcacgaa aaaggggcgt ttactggagc
    27421 cgataaacgc cgggaagggc gctttgttga ggcggacggc ggcacgctgt ttctcgatga
    27481 aattggcgat atctcgccga tgatgcaggt gcgtctgctg cgtgcgattc aggagcgcga
    27541 agttcagcgt gtcggtagca accagattat ctcggttgat gtccggctga ttgcggcgac
    27601 ccatcgcgat cttgccgcag aggtgaatgc cgggcgtttt cgccaggatc tctactatcg
    27661 cctgaatgtg gtggcgattg aagtaccatc gctgcggcaa cggcgggaag atatccctct
    27721 gctggctggc cattttctgc agcgctttgc cgagcgtaat cgcaaggcgg taaaaggttt
    27781 tacgccccag gcgatggatc tgttgattca ttacgactgg ccgggaaata ttcgtgagct
    27841 ggaaaacgcg gtggaacggg cagtggtgct gctgaccggg gaatatattt ccgaacgcga
    27901 gctgccgctg gcgattgcca gtacgccgat cccgctggga caaagtcagg atattcagcc
    27961 gttggtggaa gtggaaaaag aggtgattct ggcggcgctg gagaaaacgg gcggcaacaa
    28021 aaccgaagcc gcccgtcagt tagggatcac gcgcaaaacg ctattggcaa aactgtcgcg
    28081 ttagttctgc tcgcgttcga tagcgcgcca gccgatatct ttccggcaga agcagtcgtc
    28141 ccagtggata tcggtcatta aggcataggc gcgtttctgc gcttctgcca cggtatgacc
    28201 cagcgcggtg acgcacagta cgcgcccgcc gttggtcact acctgctcgt catccgccag
    28261 ttttgtgccc gcgtggaaca ctttgccgcc tgccacttct tccagcggca ggccgtggat
    28321 cacgtcaccg gtgcggtaat cacccggata tccacccgca gccatcacca cgccgagaga
    28381 agcgcgttca tcccactcgg acgttttctc gtccagtttg ctttcacagg ccgccaggca
    28441 gagctcaacc agatcggact tcatgcgcag cataatcggc tgggtttccg gatcgccaaa
    28501 gcggcagtta aattcaataa ccttcggatt gccctgtttg tcgatcatca ggcccgcgta
    28561 gagaaaaccg gtgtaggtgt tgccttccgc cgccatgcct ttcacggttg gccagataat
    28621 acgttccatg gtgcgctgat gaacgtcatc ggttactacc ggcgcggggg agtaagcgcc
    28681 catcccgccg gtgtttggtc cggtatcttt atcgcctacg cgtttgtgat cctggctggt
    28741 agccatcggc agcacatgct cgccgtccac catcacgata aagctcgctt cttcgccatc
    28801 gaggaactct tcgataacga tgcgatgacc cgcgtcgcca aaagcgttgc ccgccagcat
    28861 atcgtgaaca gccgcttccg cttcttccag cgtcatcgcc acgataacgc ctttcccggc
    28921 agccagaccg tccgctttaa tgacgattgg cgcgcctttc tcacgcagat acgccagcgc
    28981 aggttctacc tcggtgaagt tctggtattc cgccgtaggg atcttatggc gggccaggaa
    29041 atctttggta aacgcttttg agccttccag ttgggccgca cctgcggttg ggccgaagat
    29101 tttcagcccg gcggcgcgga aggtatcgac cacgcctttc accagcggcg cttccgggcc
    29161 gacgatggtc agatcaatct tttcgttttg tgcgaaatcc aacagcgccg ggatatcggt
    29221 cacgccaata gcaacgtttt gcagcgcggg ttccagtgca gtgcctgcat tacccggagc
    29281 aacaaaaaca gtctcaacca gcggcgactg ggccgctttc caggccagcg cgtgctcgcg
    29341 cccgccgtta ccaatcacta atactttcat ctattgctcc attaatggcg gaagtggcgc
    29401 atgtcggtga agagcatcgc aataccgtgc tcgtcggcgg cggcaatcac ttcgtcatca
    29461 cggatagaac cgccaggctg gattacgcag gtcacgcccg cagcggcggc ggcatcaata
    29521 ccgtcgcgga acgggaagaa cgcgtcagaa gccatcgagg aacctttcac ttccaggcct
    29581 tcatcggccg ctttaatacc ggcgattttt gcggagtaca cgcggctcat ctggcccgcg
    29641 ccaatgccga tagtcatatt gtttttggca tagacgatag cgttggattt cacaaacttc
    29701 gccaccttcc agcagaacag cgcatcacgc agttcctgtt cgctcggctg acgtttggtc
    29761 accacgcgca gttcttccgc accgaccatc cccaggtcac gatcctgaac cagcagaccg
    29821 ccgttcacgc gtttgaaatc gaggcccgga acacgctcgc cccactgacc gcaggtcaga
    29881 acgcgtacgt tctgtttggc ggcggtgatt ttcagggctt cttcgctggc ggacggcgca
    29941 ataatcactt caacaaactg acgagaaatg atggcctgtg cggtttccgc atccagctcg
    30001 cggttaaagg caatgatgcc gccgaatgcg gaggttgggt cggttttgta cgcgcgatcg
    30061 taagcatcaa gaatggaatt gccgatagcc acgccgcaag ggttggcgtg cttcacaatc
    30121 acacatgccg gctcggcgaa ctctttcacg cactccagcg ccgcatcggt atcggcgatg
    30181 ttgttataag agagggcttt accctgaacc tgggttgcgg tagcaacgga ggcttctttc
    30241 acattctctt ctatatagaa ggcagcctgc tggtggctgt tctcgccgta acgcatatcc
    30301 agcttcttaa tgaagttcag gttcagcgtg cgtgggaagc gaccggcggc ttctttgctt
    30361 tcaccgtggt aagccggaac catgctgccg aagtagttgg caatcatgct gtcgtaggcg
    30421 gcagtgtgtt cgaaggcttt gatggcgagg tcgaaacggg ttgcaagcgt cagcgatcct
    30481 tcgttgtcat ccatctcttt aataatggcg tcatagtcgc tgctcttcac cacgattgcg
    30541 acatctttat ggttcttggc ggcggagcgc accatcgttg ggccgccgat atcgatgttc
    30601 tcaaccgcat cttccagcga gcaaccttca cgggccacgg tctgggcgaa cggatacagg
    30661 ttaacaacca ccatatcgat aggctggatc tgatgttctt ccataatggc atcgtcctgg
    30721 ccgcgacggc ccagaatgcc accatgtact ttcggatgca gggtcttcac gcgtccatcc
    30781 atcatctccg ggaaaccggt gtaatcggaa acttcggtta ccggcagacc tttttctgct
    30841 aacagacggg cagtgccccc tgtagacagc agctccacac cgcgtgcgga aagtgcctgg
    30901 gcgaattcga cgataccggc tttgtcagaa acactgagca gagcgcggcg gactggacga
    30961 cgttgttgca tggtaaatcc cctggatttg actattacag agagcgttag ctgaattttt
    31021 cgcgaaaaac tcagctaacg cccctaacgg ggcatcctta tttttcgccc gcattgtaac
    31081 gaaaacgttt gcgcaacgct cgcgaatttt tctctttcaa tggtgatcac aattttgact
    31141 gtggttaccg tgggcaaaat acagaaatta cattgatgat tgtggataac tctgtgtgta
    31201 aaaaggtata aagcgggctt ttgctgggga atgcagcagt cagtcatttt tctgcaattt
    31261 ttctattgcg gcctgcggag aactccctat aatgcgcctc catcgacacg gcggatgtga
    31321 atcacttcac acaaacagcc ggttcggttg aagagaaaaa tcctgaaatt cagggttgac
    31381 tctgaaagag gaaggcgtaa tatacgccac ctcgcgacag tg
//
LOCUS       DACAOP010000050        31160 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.050, whole genome shotgun sequence.
ACCESSION   DACAOP010000050 DACAOP010000000
VERSION     DACAOP010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31160
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.050"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            2240..4651
                     /locus_tag="IT892_002547"
     CDS             2240..4651
                     /locus_tag="IT892_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310034.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HAP3135752.1"
                     /translation="MTNNVDVSGGILNNAGEMTAQITMNAGADSSLVNNTGTINKIVQ
                     NAGVFNNSGSVTGRMMSAGGVFNNQTDGAIMRGAALTGTAVANNEGTWNLGSSSEGNN
                     TGMLEVNNNSAFNNRGEFILDNDKNAVHINQSGTLYNTGHMNISNSSHNGAVNMWGGN
                     GRFINDGTIDVSAKSLVVSANNAGDQNAFFWNQDNGVINFDHDSASAVKVTHSNFIAQ
                     NDGIMNISGTGAVAMEGDKNAQLVNNGTINLGTAGTTDTGMIGMQLDANATADAVIEN
                     NGTINIFANDSFAFSVLGTVGHVVNNGTVVIADGVTGSGLIKQGDSINVEGMNGNNGN
                     SSEVHYGDYTLPDVPKPNTVSVTSGSDEAGGSMNNLNGYVVGTNVNGSAGKLKVNNAS
                     MNGVEINTGFTAGTADTTVSFDNVVEGSNLTDADAITSTSVVWTAKGSTDASGNVDVT
                     MSKNAYTDVATDASVNDIAKALDAGYTNNELFTSLNVGTTAELNSALKQVSGSQATTV
                     FREARVLSNRFSMLADAAPKVGNGLALNVVAKGDPRAELGNNTEYDMLALRKTIDLSE
                     SQTMSLEYGIARLDGDGAQKAGDNGVTGGYSQFFGLKHQMSFDNGMNWNNALRYDVHN
                     LDSSRSIAFGNTNKTADTDVKQQYLEFRSEGAKTFEPSEGLKVTPYAGVKLRHTLEGG
                     YQERNAGDFNLNMNSGSETAVDSIVGLKLDYAGKDGWSASATLEGGPNLSYAKSQRTA
                     SLAGAGSQHFNVDDGQKGGGINSLTSVGVKYSSKESSLNLDAYNWKEDGISDKGVMLN
                     FKKTF"
     gene            4859..5719
                     /gene="pdxI"
                     /locus_tag="IT892_002548"
     CDS             4859..5719
                     /gene="pdxI"
                     /locus_tag="IT892_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 4-dehydrogenase"
                     /protein_id="HAP3135753.1"
                     /translation="MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLRE
                     ALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLTIVTKIGARRGEDASWLPAFSPA
                     ELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIG
                     LSNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIDALAHDGIAYVPFFPLGGFTPL
                     QSSTLSDVAASLGATPMQVALAWLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEV
                     LSTLDGISRE"
     gene            5782..8088
                     /locus_tag="IT892_002549"
     CDS             5782..8088
                     /locus_tag="IT892_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing bactofilin"
                     /protein_id="HAP3135754.1"
                     /translation="MFKARNCGWIRLLPLFMLSLPVQAELRCVANAVDIESFFSAATA
                     EDKQQVEQAINSSVNLVPFGLSASNWKVHRGDLVVEGNIESNQKLIVLGNLTVKGNIS
                     TFSLSNPWVILGNVTATNIVADSPLLITGSINASGLVFIDSYYDNPSTIKGSINARGI
                     FINDIIAPVVASSTNSEFMVRASDKHDTENVKKALMIINPDAYYWGLINDEDALKEIF
                     KRSNIRMAGNVCNQMKKEALFRPKPSPELVQELQMLDEGKVAAFEGRDIATFDLAVMR
                     TLPRLKGISANLRKQLINSNDEQTIESMARYMPDNEILELTDQQLGYQPVVLGLLDRE
                     PLSVEIMTRMSRLPDGVGPLNLALRENLPLDIVMTLAKRDWDMIIQELYKDAWLLPES
                     IIDGYIRSDDSSIRQVGAGGQLTYNQAMQLANDSSNNVVTSLAFKLAEMKHHGQLLRM
                     TPQESDKVAGYLYQKFENDDDLIRVLFLALPDNLQFNFVKRMEKKSPAYFCCRDMQVI
                     HSDAALQRLLTRFNDPEGWSNLAKNQYLSTSMKQKIWQRALSHRKNNPKADSDAYETS
                     ADMILSELISHGEVDDQMLLNATALIRSDDWDFLESALISWDNLPAVVLKELQQNTPR
                     NDIWAKFFLRQENSSRAQVDEALRVYYALDPDALAQLDVLAKQPDRIWWSTLAKSNLT
                     FFKFGALNNRHTPPAVLAAEIDPEWWIVAMNNPRFPVDVLKARLKRDPLLALELVNPE
                     LDLVRQLALNGKTRAIREQAMRKLDELY"
     gene            8259..8864
                     /locus_tag="IT892_002550"
     CDS             8259..8864
                     /locus_tag="IT892_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415926.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAP3135755.1"
                     /translation="MTLYQIKPLFQSLLRPTMFWLYKHHVTANHITLAALALSLLTGL
                     LLMLAAQPILFLLLPIVLFIRMALNALDGMLARECNQQTRLGAILNETGDVISDIALY
                     LPFLFLPESNASLVILMLFCTILTEFCGLLAQTINGVRSYAGPFGKSDRALIFGLWGL
                     AVAIYPQWMQWNNLLWSIASILLLWTAINRCRSVLLMSAEI"
     gene            8864..9760
                     /locus_tag="IT892_002551"
     CDS             8864..9760
                     /locus_tag="IT892_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAP3135756.1"
                     /translation="MLEKSLATLFALLILATLINRFLLWRLPERKGGEVTLRIRTWWG
                     IVICFSMVISGPRWMTLTFFALISFLALKEYCTLISVHFPRWLYWGIPLNYLLIGFNC
                     FELFLLFIPLAGFLILATGQVLVGDPSGFLHTVSAIFWGWIMTVFALSHAAWLLMLPT
                     TNIQGGALLVLFLLALTESNDIAQYLWGKSCGRRKVVPKVSPGKTLEGLMGGVITIMI
                     ASLIIGPLLTPLNTLQALLAGLLIGISGFCGDVVMSAIKRDIGVKDSGKLLPGHGGLL
                     DRIDSLIFTAPVFFYFIRYCCY"
     gene            9776..11533
                     /locus_tag="IT892_002552"
     CDS             9776..11533
                     /locus_tag="IT892_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional alpha/beta hydrolase/class I
                     SAM-dependent methyltransferase"
                     /protein_id="HAP3135757.1"
                     /translation="MENSRIPGEHFFTTSDNTALFYRHWPALQPGAKKVIVLFHRGHE
                     HSGRLQHLVDELAMPDTAFYAWDARGHGKSSGPRGYSPSLARSVRDVDEFVRFAASDS
                     QVGLEEVVVIAQSVGAVLVATWIHDYAPAIRGLVLASPAFKVKLYVPLARPALALWHR
                     LRGLFFINSYVKGRYLTHDRQRGASFNNDPLITRAIAVNILLDLYKTSERIIRDAAAI
                     TLPTQLLISGDDYVVHRQPQIDFYQRLRSPLKELHLLPGFYHDTLGEENRALAFEKMQ
                     SFISRLYANKSQKFDYQHEDCTGPSADRWRLLSGGPVPLSPVDLAYRFMRKAMKLFGT
                     HSSGLHLGMSTGFDSGSSLDYVYQNQPQGSNAFGRLVDKIYLNSVGWRGIRQRKTHLQ
                     ILIKQAVADLHAKGLAVRVVDIAAGHGRYVLDALANEPAVSDILLRDYSELNVAQGQE
                     MIAQRGMSGRVRFEQGDAFNPEELSALTPRPTLAIVSGLYELFPENEQVKNSLAGLAN
                     AIEPGGILIYTGQPWHPQLEMIAGVLTSHKDGKPWVMRVRSQGEMDSLVRDAGFDKCT
                     QRIDEWGIFTVSMAVRRDN"
     gene            11523..12839
                     /locus_tag="IT892_002553"
     CDS             11523..12839
                     /locus_tag="IT892_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310040.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2/dual specificity phosphatase
                     family protein"
                     /protein_id="HAP3135758.1"
                     /translation="MITERRNVLLQGAGWLLLLAPFFFFTYGSLNQFTAVQDLNSHDI
                     PSQVFGWETAIPFLPWTIVPYWSLDLLYGFSLFVCSTTFEQRRLVHRLILATVMACCG
                     FLLYPLKFSFIRPEVSGVTGWLFSQLELFDLPYNQSPSLHIILCWLLWRHFRQHLAER
                     WRKVCGGWFLLIAISTLTTWQHHFIDVITGLAVGMLIDWMVPVDRRWNYQKPDQRRIK
                     IALPYVVGAGSCIVLMELMMMIQLWWSVWLCWPVLSLLIIGRGYGGLGAITTGKDSQG
                     KLPPAVYWLTLPCRIGMWLSMRWFCRRLEPVSKMTAGVYLGAFPRHIPAQNAVLDVTF
                     EFPRGRATKDRLYFCVPMLDLVVPEEGELRQAVAMLETLREEQGSVLVHCALGLSRSA
                     LVVAAWLLCYGHCKTVNEAISYIRARRPQIVLTDEHKAMLRLWENR"
     gene            complement(12893..13498)
                     /gene="azoR"
                     /locus_tag="IT892_002554"
     CDS             complement(12893..13498)
                     /gene="azoR"
                     /locus_tag="IT892_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAP3135759.1"
                     /translation="MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLA
                     ANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNIS
                     TQLKNYFDLVARAGVTFRYTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTF
                     LGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVSA"
     gene            13699..17601
                     /gene="hrpA"
                     /locus_tag="IT892_002555"
     CDS             13699..17601
                     /gene="hrpA"
                     /locus_tag="IT892_002555"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415931.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HAP3135760.1"
                     /translation="MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQ
                     AIFQEMAKEIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGET
                     GSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRF
                     SDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP
                     RRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQ
                     AIFDAVDELSQESHGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNR
                     VFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS
                     ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAA
                     FPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLE
                     AQKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLG
                     EQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHI
                     ALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGR
                     IAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQI
                     DPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEF
                     YDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGN
                     LKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPV
                     RRNFVPAPNYAEAFLGRVKPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKIT
                     FRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYE
                     QKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEK
                     LPNKAKLGLYFNPYGKVLELIDDCISCGVDKLIDANGGPVWTEEGFAALHEKVRAELN
                     DTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFK
                     RLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLPPARREDEDVK
                     EIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG"
     gene            17873..18673
                     /locus_tag="IT892_002556"
     CDS             17873..18673
                     /locus_tag="IT892_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP3135761.1"
                     /translation="MNITPFPTLSPATIDAINVIGQWLAQDDFSGEVPYQADCVILAG
                     NAVMPTIDAACKIARDQQIPLLISGGIGHSTTFLYSAIAQHPHYNTIRTTGRAEATIL
                     ADIAHQFWHIPHEKIWIEDQSTNCGENARFSIALLNQAVERVHTAIVVQDPTMQRRTM
                     ATFRRMTGDNPDAPRWLSYPGFVPQLGNNADSVIFINQLQGLWPVERYLSLLTGELPR
                     LRDDSDGYGPRGRDFIVHVDFPAEVIHAWQTLKHDAVLIEAMESRSLR"
     gene            18870..20309
                     /gene="aldA"
                     /locus_tag="IT892_002557"
     CDS             18870..20309
                     /gene="aldA"
                     /locus_tag="IT892_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HAP3135762.1"
                     /translation="MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAE
                     DARKAIDAAERAQPEWEALPAIERASWLRKISAGIRERASEISALIVEEGGKIQQLAE
                     VEVAFTADYIDYMAEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIA
                     RKMAPALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAG
                     NPKVAMVSMTGSVSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDS
                     RVINSGQVCNCAERVYVQKGIYDQFVNRLGEAMQAVQFGNPAERNDIAMGPLINAAAL
                     ERVEQKVARAVEEGARVAFGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVLPVV
                     AFDTLEDAISMANDSDYGLTSSIYTQNLNVAMKAIKGLKFGETYINRENFEAMQGFHA
                     GWRKSGIGGADGKHGLHEYLQTQVVYLQS"
     gene            complement(20351..21351)
                     /gene="gap"
                     /locus_tag="IT892_002558"
                     /pseudo
     CDS             complement(20351..21351)
                     /gene="gap"
                     /locus_tag="IT892_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310049.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
     gene            21540..22070
                     /gene="cybB"
                     /locus_tag="IT892_002559"
     CDS             21540..22070
                     /gene="cybB"
                     /locus_tag="IT892_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b561"
                     /protein_id="HAP3135763.1"
                     /translation="MENKYSRLQISIHWLVFLLVIAAYCAMEFRGFFPRSDRPLINMI
                     HVSCGISILVLMVVRLLLRLKYPTPPIIPKPKPMMTGLAHLGHLVIYLLFIALPVIGL
                     VMMYNRGNPWFAFGLTMPYASEANFERVDSLKSWHETLANLGYFVIGLHAAAALAHHY
                     FWKDNTLLRMMPRKRS"
     gene            22315..22488
                     /locus_tag="IT892_002560"
     CDS             22315..22488
                     /locus_tag="IT892_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135764.1"
                     /translation="MKKLALILFMGTLVSFYADAGRKPCSGSKGGISHCTAGGKFVCN
                     DGSISASKKTCTN"
     gene            complement(22560..22709)
                     /gene="hokB"
                     /locus_tag="IT892_002561"
     CDS             complement(22560..22709)
                     /gene="hokB"
                     /locus_tag="IT892_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokB"
                     /protein_id="HAP3135765.1"
                     /translation="MKHNPLVVCLLIICITILTFTLLTRQTLYELRFRDGDKEVAALM
                     ACTSR"
     gene            23108..24748
                     /gene="trg"
                     /locus_tag="IT892_002562"
     CDS             23108..24748
                     /gene="trg"
                     /locus_tag="IT892_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein Trg"
                     /protein_id="HAP3135766.1"
                     /translation="MNTTPSQRLGFLHHIRLVPLFACILGGILVLFALSSALAGYFLW
                     QADRDQRDVTAEIEIRTGLANSSDFLRSARINMIQAGAASRIAEMEAMKRNIAQAESE
                     IKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAIINHE
                     SEQIRPLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLIT
                     FMVLRRIVIRPLQHAAQRIEKIASGDLTMNDEPAGRNEIGRLSRHLQQMQHSLGMTVG
                     TVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAASMEQLTATVKQNADNAHHA
                     SKLAQEVSIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAV
                     EAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTM
                     STIVDAVASVTHIMQEIAAASDEQSRGITQVSQAISEMDKVTQQNASLVEEASAAAVS
                     LEEQAARLTEAVDVFRLHKHSVSAEPRGAGEPVSFATV"
     gene            complement(24786..25709)
                     /locus_tag="IT892_002563"
     CDS             complement(24786..25709)
                     /locus_tag="IT892_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415939.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3135767.1"
                     /translation="MEKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSK
                     TLNELEQLTGARLFERGRQGAQLTLPGEQFLTHAVRVLDAINTAGRSLHRKEGLNNDV
                     VRVGALPTAALGILPSVIGQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSD
                     PELMTGLNYELLFLESLKLVVRPNHPLLQENVTLSRVLEWPVVVSPEGTAPRQHSDAL
                     VQSQGCKIPSGCIETLSASLSRQLTVEYDYVWFVPSGAVKDDLRHATLVALPVPGHGA
                     GEPIGILTRVDATFSSGCQLMINAIRKSMPF"
     gene            25926..27269
                     /locus_tag="IT892_002564"
     CDS             25926..27269
                     /locus_tag="IT892_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP3135768.1"
                     /translation="MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVL
                     ENNPQLHEKMVNADELARLNVERHGAIRVGTAQELATLRRMFAIMGMYPVSYYDLSQA
                     GVPVHSTAFRPIDDASLARNPFRVFTSLLRLELIENEILRQKAAEILRQRDIFTPRCR
                     QLLEEYEQQGGFNETQAQEFVQEALETFRWHQSATVDEETYRALHNEHRLIADVVCFP
                     GCHINHLTPRTLDIDRVQSMMPECGIEPKILIEGPPRREVPILLRQTSFKALEETVLF
                     AGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNLTHQMHLQETFRTFP
                     DSEFLMRQQGLAWFRYRLTPSGEAHRQAIHPGDDPQPLIERGWVVAQPITYEDFLPVS
                     AAGIFQSNLGNETQTRSHGNASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL"
     gene            27494..29149
                     /locus_tag="IT892_002565"
     CDS             27494..29149
                     /locus_tag="IT892_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415941.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan biosynthesis protein"
                     /protein_id="HAP3135769.1"
                     /translation="MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQR
                     FDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLD
                     AQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAG
                     FRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFW
                     FDTVKPGATTFTVYALLDSASITGAYKFTIHCEKSQVIMDVENHLYARKDIKQLGIAP
                     MTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNP
                     KGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVC
                     FWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFSEGWAPGEHYPEK
                     WARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSD
                     STDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS"
     gene            29289..29513
                     /locus_tag="IT892_002566"
     CDS             29289..29513
                     /locus_tag="IT892_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415943.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HAP3135770.1"
                     /translation="MFPEYRDLISRLKNENPRFMSLFDKHNKLDHEIARKEGSDGRGY
                     NAEVVRMKKQKLQLKDEMLKILQQESVKEV"
     gene            29576..30115
                     /gene="rimL"
                     /locus_tag="IT892_002567"
     CDS             29576..30115
                     /gene="rimL"
                     /locus_tag="IT892_002567"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12-serine
                     acetyltransferase"
                     /protein_id="HAP3135771.1"
                     /translation="MTETIKVSESLELHAVAENHVKPLYQLICKNKTWLQQSLNWPQF
                     VQSEEDTRKTVQGNVMLHQRGYAKMFMIFKEDELIGVISFNRIEPLNKTAEIGYWLDE
                     SHQGQGIISQALQALIHHYAQSGELRRFVIKCRVDNPQSNQVALRNGFILEGCLKQAE
                     FLNDAYDDVNLYARIIDSQ"
     gene            complement(30107..31087)
                     /locus_tag="IT892_002568"
     CDS             complement(30107..31087)
                     /locus_tag="IT892_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135772.1"
                     /translation="MRKYRLSEEQRAFSYQEDGTKKNVLLRQIIAISDFNDVIAGTAG
                     GWIDRETVLAQEGNCWIYDQNAIAFGGAVISGNTRITGTSVLWGEVYATDNVWIDNSE
                     ISQGAYISDSVTIHDSLVYGQCRIFGHALIDQHSMIVAAQGLTPDHQLLLQIYDRARV
                     SASRIVHQAQIYGDAVVRYAFIEHRAEVFDFASIEGNEENNVWLCDCAKVYGHAQVKA
                     GIEEDAIPTIHYSSQVAEYAIVEGNCVLKHHVLVGGNAVVRGGPILLDEHVVIQGESR
                     ITGAVIIENHVELTDHAVVEAFDGDTVHVRGPKVINGEERITRTPLAGLL"
BASE COUNT         7997 a         7100 c         8141 g         7922 t
ORIGIN      
        1 ggataacaag ggcaccatga ccgtcaccga tccggagtcc atcggtatcc agattgacgg
       61 cgaccaggcc atcgtcaata acgaaggcga gagcactatc accaatggcg gcaccggcac
      121 tcagatcaac ggtaacgacg ccaccgcgaa taacagtgga aaaaccactg ttgatggaaa
      181 agattccacg ggtaccaaaa tcgcgggcaa tatcggcatt gtaaatctgg atggtagcct
      241 gactgttaca ggcggtgcgc atggtgttga gaacattggt gacaacggca cggttaacaa
      301 caaaggagat attgttgttt ccgatactgg atcgattggc gtgctcatca acggtgaggg
      361 ggcaacagta tccaatacgg gtgatgttaa cgttagcaat gaagcgacag ggttcagcat
      421 cacaaccaac agtgggaagg tttcgctggc aggcagtatg caggttggcg atttctcgac
      481 cggggtagat cttaatggca acaataacag cgtgacgctg gcggcaaaag atctaaaagt
      541 ggtcgggcag aaagcgacgg gcataaacgt ttctggcgat gcgaatacag tgaatatcac
      601 tggtaacgtt ctggttgata aggataaaac cgcagacaat gcggcggaat atttcttcga
      661 tccatccgtg ggtatcaacg tttacggcag tgataataac gtgacgctgg atggaaagtt
      721 aactgttgta tcagacagtg aggttacttc tcgtcagagt aatttatttg atggcagcgc
      781 agagaaaacg tcaggtctgg ttgtgattgg cgatggcaat accgttaata tgaatggtgg
      841 acttgaactg attggagaga aaaacgcgct tgcagatggg tcgcaggtta cttccttgcg
      901 cacaggatat agttatacca gcgttattgt cgttagtggt gagtcgtcgg tatatctgaa
      961 tggagatacg acaatcagcg gagaattccc tctggggttt gccggggtta ttcgggtaca
     1021 ggataaagct ttgctggaaa ttggcagtgg cgctacgcta acaatgcagg atattgacag
     1081 ttttgaacat catgggacaa gaaccccaga acttacttat gctgattccg gtgcgaaaat
     1141 tgttaataaa ggtactgttg aaattcagaa tttaggtttt gcttttgtta ctggtgaaaa
     1201 tacaacaggt ataaatagtg gcacgatctc gttattacaa aatggtaaag atccggcacc
     1261 gtctcccatt gttttactgg ctactaacgg agggagcgcc actaatgcag gtacgatcac
     1321 aggtaaagtg acggaacaac atagcgtatt taacaagtat tcaacgggca catcgaattc
     1381 atttattttt aataacgatg tcagtagcat aacagggtta gtcgctcaat cgaatagcac
     1441 aattatcaat actgacagcg gcatcattga tttgtatggt cgtggtagtg tcggcatgct
     1501 tgctatagca gattcaacag cagaaaatca gggtaaaatt acactggatt ctatgtgggt
     1561 agatgcaaat gacactaccg caatgcgaga tatagctagc aacagcgcca ttgacttcgg
     1621 tacaggtgtg ggagttggta ctgatagtta tagtggtgca gggaaaaatg caacagcaat
     1681 taaccaattg ggcggtgtta taactattta taacgccggc gcaggtatgg cggcctatgg
     1741 cgccagcaat acagttatta accaggggac gattaacctc gaaaaaaatg ataattatga
     1801 cgatagtctg gcagcaaata ctctggtagg gatggctgtt tatgagcatg gtactgctat
     1861 caacgaccag acgggtgtta tcaatatcaa tgttggtact ggtcaggcgt tttataacga
     1921 tggcacagga acaattgtta actatggtac aatctgcact ttcggcgtgt gccaatcggg
     1981 gaatgagtac aataatacag atgatttcac ctcactgatc tataccggtg gcgatacgat
     2041 tacacgaagc ggagaaactg taacgctaaa taaatctgct gctgtgactg ataagctggc
     2101 tgggaatgtt gttaatagcg gaacgctttc cggtgatcaa attacggtat caagcggtct
     2161 tctggaaaat accagcggtg gcatcatcaa taacttagta aaacttgaca agggtgccgt
     2221 cattaaaaat gccggggtga tgacgaataa cgtcgatgtt agcggtggaa tcctcaataa
     2281 tgccggagaa atgactgcgc aaattaccat gaatgctggt gctgatagtt cgttagtgaa
     2341 caacaccgga accatcaata aaatcgtgca gaacgcgggg gtattcaata atagtggcag
     2401 tgtaacaggg cggatgatgt cggctggcgg ggtctttaat aatcaaactg acggggcgat
     2461 tatgagaggt gctgcgctga caggtactgc agtggcaaat aacgaaggaa cctggaacct
     2521 cggaagtagt agtgagggta acaacaccgg gatgctggaa gttaataata attcagcttt
     2581 caataaccgc ggcgagttta ttcttgataa cgacaagaat gctgtgcaca tcaaccagtc
     2641 cggtacgctt tataataccg gtcacatgaa catcagtaat tcttcccaca acggagccgt
     2701 taatatgtgg ggcggaaatg gtcgttttat caatgacgga acgattgatg tttctgcgaa
     2761 gtcactggta gtcagcgcta ataatgccgg cgatcagaat gccttcttct ggaaccagga
     2821 taacggggtc atcaacttcg atcacgacag cgccagtgcc gtgaaagtca cccacagcaa
     2881 ctttattgcc cagaatgacg gcatcatgaa catcagcggc accggtgctg tggctatgga
     2941 aggtgataag aacgcgcagc tggttaacaa tggcaccatc aacctcggta ccgcaggcac
     3001 tactgacacg ggtatgatcg gtatgcaact cgatgccaac gccacggcgg atgcggtaat
     3061 cgaaaacaac ggcaccatca atatcttcgc caatgactcg tttgcattta gcgtactggg
     3121 tacagtaggt catgtggtta acaacggcac ggtggtgatt gccgatgggg ttacgggttc
     3181 tggactgatc aagcagggcg acagcatcaa tgttgaaggt atgaacggta acaacggtaa
     3241 tagcagcgaa gtgcattatg gcgactatac gttgccggat gtgccgaagc ccaatacggt
     3301 tagtgtaacg tcgggaagtg atgaggctgg tggcagcatg aacaacctca acggctatgt
     3361 cgtcggtacc aacgttaacg gcagcgccgg gaagctgaag gttaacaatg ccagcatgaa
     3421 cggcgtggag attaacacgg gctttaccgc tggtacggca gacaccactg tgagttttga
     3481 taacgtagtg gaaggtagca acctgaccga cgctgacgcc atcacctcaa cgtccgtggt
     3541 atggactgcc aaaggcagca ccgatgccag cggtaacgtt gacgtcacca tgagcaaaaa
     3601 tgcctacacc gatgtggcaa cagatgcctc ggtgaatgac atcgcgaaag cactggatgc
     3661 gggttacacc aacaacgaac tgtttaccag cctgaacgtc ggcacgactg ctgaactgaa
     3721 cagtgctctg aaacaggtca gcggtagcca ggcgaccacg gtattccgcg aagcgcgcgt
     3781 gttaagcaac cgctttagta tgctggcaga tgccgcgccg aaagtgggta acggtctggc
     3841 gctcaacgtt gtcgcgaaag gcgatccgcg tgccgagtta ggtaataata ccgaatacga
     3901 catgctggca ttgcgtaaaa ctatcgacct gagcgaaagc cagacgatga gtctggagta
     3961 cggtatcgct cgtctcgatg gtgatggtgc gcagaaagcg ggtgataatg gcgttacagg
     4021 cggttatagc cagttttttg gcctgaaaca tcagatgtcg ttcgataacg gcatgaactg
     4081 gaataacgcc ttgcgttacg acgttcacaa ccttgacagc agccgctcga ttgcatttgg
     4141 caacacgaac aaaacggctg ataccgacgt gaaacagcag tacctggagt tccgcagcga
     4201 aggggcgaag actttcgaac cgagcgaagg actgaaggtt acgccatatg cgggtgtaaa
     4261 actgcgtcac acactggaag gtggctatca ggagcgcaat gccggagact ttaacctgaa
     4321 tatgaacagt ggcagcgaaa cggcggtgga cagcatcgtc gggctgaaac tggactacgc
     4381 aggtaaagac ggctggagcg ctagcgctac gctggaaggc gggccgaacc tgagctacgc
     4441 gaagagccag cgtacggcaa gcctggcagg cgcaggcagt cagcacttta acgtcgatga
     4501 cggtcagaag ggcggcggca tcaatagcct gacaagcgtc ggcgtgaagt acagcagcaa
     4561 agaaagttcg ctgaatctgg atgcgtacaa ctggaaagag gatggcatca gcgataaagg
     4621 cgtgatgctg aacttcaaga aaacgttcta atttttagca tgtgatccct aaaccgcaac
     4681 gctgatacag gttgcggttt ttttattgcc ggatgtggta cgtgacgcgt tttgttttgt
     4741 gtctttcagg acaatagagc aactcatcca gtaatcttgt ttacaccttc gcattattta
     4801 tctcttttcg tttctatact gatttttctt aatccgtttt attacagggc agggtgcgat
     4861 gagcagcaat acatttactc tcggtacaaa atccgttaac cgtcttggtt atggcgcgat
     4921 gcaactggca ggtcctggag tttttggccc cccacgagat cgccacgtcg ctataaccgt
     4981 gctgcgtgag gcgctggcat tgggcgtcaa tcatattgat accagcgact tttatggtcc
     5041 gcacgtcacc aatcagatta tccgcgaagc gctttatcct tactctgacg acctgacaat
     5101 tgtcactaaa attggtgcgc ggcgtggaga ggacgcatcc tggttgcccg cattttctcc
     5161 ggcagagctg caaaaagcgg tgcacgataa tctacgtaat ctcgggctgg acgtgctgga
     5221 tgtggttaac ctgcgcgtta tgatggggga tggtcatggc ccagcggaag gatcgattga
     5281 ggccagcctg accgtgctgg cagagatgca acaacaaggc ctggtaaaac atattggcct
     5341 gagcaacgtc acaccgacgc aggttgcaga ggcgcgcaag attgccgaaa ttgtctgtgt
     5401 gcaaaacgaa tacaacatcg cgcaccgtgc tgatgatgca atgattgatg ctttggccca
     5461 cgatggcatt gcctacgtgc cgttcttccc gctcgggggc tttacaccgc tgcaatcgtc
     5521 cacactttcc gatgttgctg cgagcctggg tgcaacacca atgcaggtgg cgctggcgtg
     5581 gctgttacag cgttcaccga atattttgct gatcccaggg acgtcttcgg ttgcgcattt
     5641 acgggagaat atggctgctg aaaaattgca tctttctgag gaagtgttgt ctacgttgga
     5701 tggtatttcg cgagaataac gaatatacaa aagggaaaga tgcatttccc tttttttctt
     5761 ttttaatggc atggagtgca tatgtttaag gccaggaatt gcggctggat acgtttactg
     5821 cccctgttta tgctgagtct accagtacag gcggaacttc gatgtgttgc aaatgcagtt
     5881 gatattgaat catttttttc tgcggctacc gctgaagata aacaacaagt tgaacaagct
     5941 atcaacagta gcgtgaatct tgtccccttc ggtttatctg catcgaactg gaaagtgcat
     6001 cgtggcgatt tagtggtaga aggtaatata gagagtaatc aaaaattgat tgttcttggg
     6061 aatttgacag tcaaaggtaa tatttccact ttctctcttt ctaatccatg ggttattctc
     6121 ggtaacgtga cggcaacgaa tatagttgcg gattcaccac tgttaattac cggttcgata
     6181 aatgcaagtg gactggtatt tatcgactca tattacgata atccgtctac gattaagggg
     6241 agtattaatg cgcgtgggat atttatcaat gacataattg cacctgttgt tgcgtcttcg
     6301 acaaatagtg aattcatggt ccgtgcgagt gacaaacatg acactgaaaa tgtcaaaaaa
     6361 gcgctgatga taataaatcc tgatgcatat tattgggggc taattaatga tgaagatgct
     6421 ctgaaagaaa tttttaagcg aagcaatatt cgcatggcag ggaatgtctg taatcagatg
     6481 aaaaaagaag cgctgtttcg ccctaagcct tctcctgagt tagtgcaaga attgcaaatg
     6541 ctggatgaag gcaaagttgc tgcatttgaa ggacgagaca ttgcgacatt tgatcttgcc
     6601 gtaatgcgaa ctctcccaag gcttaaagga atttcagcta acctacgcaa acaacttatt
     6661 aatagcaatg atgaacaaac gattgaaagt atggcgagat atatgcctga caatgagatt
     6721 ctggagttga ccgatcagca attgggttac cagcctgttg ttctggggtt gctcgaccgt
     6781 gaaccgctct ctgtcgaaat aatgacgcga atgagtcgtc tacctgatgg tgtcggtccg
     6841 ttgaatcttg cgctacgtga aaatctccct ctggatatcg tcatgactct ggcgaaaaga
     6901 gattgggata tgatcattca ggagctttat aaagatgcgt ggttattgcc tgaatccatt
     6961 attgatggct atatccgcag tgatgattcc tctattcgtc aggtcggtgc tggaggacaa
     7021 ctcacctaca atcaggcaat gcagttggcg aacgattcat caaacaatgt tgtcacaagc
     7081 ttagcgttca agctggcaga gatgaaacac catggtcaat tgttgcggat gacgccacaa
     7141 gagagtgaca aagttgcagg ctatttatac caaaaattcg agaatgacga tgatctaata
     7201 cgtgtgttat ttttagcatt gccagataac ttacagttta attttgttaa aaggatggag
     7261 aaaaaatccc cggcctactt ttgctgtcgg gatatgcagg taattcactc tgacgctgct
     7321 ttacaacggt tattgacacg tttcaacgat cctgaagggt ggagtaatct ggcgaaaaat
     7381 cagtatctga gcacgtcgat gaaacaaaaa atttggcaac gtgctttatc gcatcggaaa
     7441 aataatccga aagcagattc agatgcatat gaaaccagcg ctgatatgat tttgtctgag
     7501 ctgattagcc acggcgaagt tgatgaccag atgctattaa atgccaccgc cctgatacgt
     7561 tcggacgact gggacttttt agagagtgca ttaattagtt gggataattt acccgctgtt
     7621 gttctcaagg aattacagca aaacacgcca cgcaatgata tttgggcgaa gttttttctg
     7681 aggcaggaaa acagttcccg tgcgcaggtt gacgaagcgt tacgtgttta ttatgcacta
     7741 gaccccgatg cgttagcaca actggatgta ctggcaaaac aaccggatcg tatatggtgg
     7801 agtacactgg cgaaaagcaa tctcacattt ttcaagttcg gcgcacttaa caaccgccac
     7861 acaccgcctg cagtactggc ggcagaaatt gatcccgagt ggtggattgt ggcgatgaat
     7921 aatccccgtt ttccagttga tgtattaaag gcgaggctga aacgtgatcc tttgctggcg
     7981 ttagagcttg ttaaccctga actggattta gtccgccagc tggcgcttaa cggtaagacg
     8041 cgcgcaatac gggaacaagc gatgagaaaa cttgatgagt tgtattgatc cacaacgtaa
     8101 tgttttttaa ctatctgatt aattggggat aatcattcct gacagtgagt ccccaatacc
     8161 ttgatatatt ctgaattttt aatgaaacgg cgtgttgcga tatctccgtc aggggaattg
     8221 atgcaccata gcgcaaaccg aattatcaag gattgataat gacgctctac cagataaaac
     8281 cgctctttca gtcgctgtta aggccgacga tgttttggct ttataagcac cacgttacag
     8341 cgaatcacat cactcttgct gcactggcgc tttctcttct taccggattg ctgttgatgt
     8401 tggcggcaca acccatcctc tttttgctat tgcccatcgt gctttttatc cgtatggcgc
     8461 tcaatgcgct ggatggcatg ttggcgcgtg agtgcaacca gcaaacacgt ctgggggcga
     8521 ttttgaatga gactggcgat gttatttccg atattgcgct ctatttacca tttttatttt
     8581 taccggaaag taacgcatca ctcgtgatac tcatgttatt ttgcaccata ttgaccgagt
     8641 tttgcggttt actcgcgcag acgattaacg gtgttcgcag ttatgccggt ccatttggca
     8701 aaagcgatcg cgcgttaata tttggtctgt ggggtctggc cgttgccatt tatccacagt
     8761 ggatgcagtg gaataatctt ttatggagca ttgcttcaat tctgcttctc tggactgcga
     8821 ttaatcgttg tcggagtgtg cttcttatga gcgctgaaat ataatgctgg aaaaatctct
     8881 ggcaacactt ttcgcgttgt taattttagc aacgctgata aaccgttttc tgctatggcg
     8941 gttaccggag agaaaagggg gtgaggttac attacgtatt cgtacctggt ggggcatcgt
     9001 catttgtttt tcaatggtga tttcaggtcc acgctggatg acgttgacgt tttttgcgct
     9061 gataagtttt ctggcattga aagaatattg tacgcttata tctgtacatt ttccgcgttg
     9121 gttatattgg ggtattcctc ttaactattt gcttatcggt tttaattgct ttgagctgtt
     9181 tctgttattt atacctttgg ctgggtttct gatattagcc accgggcaag ttttagtggg
     9241 tgacccctct ggttttctgc ataccgtgag cgccattttt tggggctgga taatgaccgt
     9301 tttcgccttg agtcatgccg cctggttatt aatgttgcca accacaaata tccagggcgg
     9361 ggcgttactg gtgttatttc ttttggcatt aaccgagtca aacgatattg cacagtattt
     9421 atggggaaaa tcctgcggca gaagaaaagt ggtccctaaa gtcagcccgg gaaaaacatt
     9481 ggaaggtctg atgggcggcg tcatcaccat catgattgcg tcactgatta tcggaccgtt
     9541 actgacaccg ctaaatacat tacaggcatt attagcgggt ttgttaattg gtattagtgg
     9601 tttttgcggc gatgtcgtga tgtcagccat caaacgagat attggtgtta aagatagcgg
     9661 aaaactattg ccaggacatg gcggactcct tgacaggatt gactcattaa ttttcaccgc
     9721 tccggtattt ttttatttta tacgctactg ctgttactga aggaaaatag agaaaatgga
     9781 aaattcacgc atccctgggg aacatttttt taccaccagt gataatacag cgttgtttta
     9841 tcggcactgg cccgctttac agcccggggc gaaaaaggtc atcgtcttat ttcatcgcgg
     9901 gcatgaacat tctggtcgtc tacaacatct cgttgatgaa ctggcgatgc cagatactgc
     9961 tttttatgcc tgggatgccc gagggcatgg aaaaagttcg gggccgcgtg gttatagccc
    10021 atctcttgcg cgttcagtgc gggatgtcga tgaatttgtc cgttttgctg ccagcgacag
    10081 ccaggttgga ctggaagagg tggtagtgat cgcgcaaagc gtcggcgcag tgctggttgc
    10141 cacatggatt catgattatg cacctgcaat tcgcgggctg gtgctggctt ctccggcctt
    10201 taaggttaaa ttgtatgtgc cgctggcacg tcctgcgctg gcgttatggc atcgtctgcg
    10261 tggtctgttt tttattaatt cctatgtgaa aggacgctat ttgacccacg atcggcaacg
    10321 gggggcgagt ttcaataatg atccgctgat cacacgggcg attgccgtta atatcttgct
    10381 cgatctctac aaaacgtctg aacgtattat tagagatgcg gcggcgatta cgctccccac
    10441 gcaacttctg atatcaggcg atgactatgt ggtgcatcgc caaccgcaga ttgattttta
    10501 tcagagatta cgtagccctc tgaaagagct gcatctgctg ccaggctttt atcacgacac
    10561 gttgggtgaa gagaacaggg cgctggcatt tgaaaaaatg caaagcttta ttagtcgttt
    10621 atatgctaac aaatcgcaaa aatttgatta tcagcatgaa gactgcacag gaccatcagc
    10681 ggatcgatgg cggctacttt ctggtggacc cgtgccatta tcgccggttg atttagcgta
    10741 tcgctttatg cgaaaggcga tgaaattgtt cgggacgcac tcttcgggcc tgcatctcgg
    10801 aatgagcacc ggctttgatt caggcagttc gctggattat gtctatcaaa atcaaccgca
    10861 aggtagtaac gcattcgggc gtttagtcga caaaatctac ctgaacagtg ttggctggcg
    10921 cggtattcgc cagcgcaaaa cccatttaca aatactgatt aaacaagccg ttgccgatct
    10981 ccacgccaaa ggtttagccg tccgcgtggt tgacattgcc gcagggcatg ggcgctatgt
    11041 actggatgcg ctggcaaacg agcctgccgt aagcgatatt ttgttacgtg attacagcga
    11101 gttaaatgtt gcacaggggc aagagatgat tgctcaacgg ggaatgtctg ggcgggtgcg
    11161 ttttgaacag ggcgatgcgt ttaacccgga ggaactcagc gcgttaactc cgcggcctac
    11221 gctggcgatt gtctctggcc tgtatgagct ttttcccgaa aatgagcagg taaaaaactc
    11281 actcgcaggt cttgccaatg ccatcgaacc gggcggcatt ctcatctaca ccgggcagcc
    11341 gtggcaccct caactggaga tgattgccgg ggtgttaacc agtcataaag atggtaaacc
    11401 gtgggtaatg cgcgtgcgtt cgcaagggga gatggattca ctcgtgcgtg atgccggatt
    11461 tgataaatgc acacaacgga ttgatgagtg gggtattttt acggtttcga tggcggtgcg
    11521 tcgtgataac tgaacgtcgg aacgtattgc tacaaggcgc tggctggtta ttgttgctgg
    11581 ccccgttttt cttcttcacc tatggatctc ttaatcagtt caccgcggtt caggacctta
    11641 acagccatga tatccccagt caggtattcg gttgggaaac ggcgatccct tttcttccct
    11701 ggactattgt tccttactgg agtctggatc ttttatatgg attttcgctg ttcgtttgta
    11761 gcacgacatt cgaacagcgc cgacttgtcc accggcttat tctggcaacg gtaatggcct
    11821 gctgcggttt tttgctctat ccgctgaagt ttagttttat ccgtcctgaa gtgagtgggg
    11881 tgacgggatg gctattttcg caacttgaac tgtttgatct gccttataac cagtctcctt
    11941 cgctgcatat tattctctgc tggctacttt ggcgtcactt tcgtcagcat ctggctgaga
    12001 ggtggcgtaa agtctgcggc ggatggtttt tactcatcgc catttcgacg ctgacgacct
    12061 ggcagcatca ttttattgat gtcatcacag ggctggcggt aggtatgttg attgactgga
    12121 tggtgcccgt cgaccgtcgt tggaattatc agaaacctga tcaacgtcga atcaaaatag
    12181 cactgcccta tgtcgtaggc gcgggctcgt gcattgtatt gatggagcta atgatgatga
    12241 ttcagttatg gtggtcagtc tggttatgtt ggccagtatt atcgctactc ataattggcc
    12301 gtgggtacgg tgggcttggc gcgataacaa cagggaaaga tagtcagggg aaactaccgc
    12361 ccgccgttta ctggctgaca ttgccctgcc gcatcgggat gtggctgtct atgcgttggt
    12421 tttgtcgtcg cctggagccg gtgagcaaaa tgactgctgg tgtttattta ggggcgtttc
    12481 cacgacatat tccggcacag aatgcggttc tggacgtcac ctttgaattc cctcgcggac
    12541 gagccacaaa agatcgactc tatttttgtg taccgatgct ggatctggtg gttccggaag
    12601 agggggagct ccgacaggcc gtggcgatgc tggaaacatt acgcgaagag caaggcagcg
    12661 ttctggtcca ttgtgcattg ggattatcgc gcagtgcgct ggtggtggcg gcatggttgt
    12721 tatgttacgg acactgtaaa accgttaatg aagcgattag ctatattcga gccagacgcc
    12781 cgcagattgt gctgacagac gagcacaaag cgatgctgag attatgggaa aacaggtaag
    12841 tggattgaga tgtggactga atatctacag tccacatcaa gaccgtgtcc ggttatgcag
    12901 aaacaatgct gtcgatggct gcttttgcgt cagactgtgc tttcgctgcc atttccggac
    12961 cgtatgcgat cccttcggcg aagacaaatt tcacatcggt aatgccgata aagccgagga
    13021 acgtggacag atacggcgtc accaggtccg ttggtccatc tttgtggatc ccgccgcggc
    13081 tggtaataac gatggctttt ttacccgtta ccagaccttc cggaccgttc tcggtatagc
    13141 ggaaagtaac gcctgcgcgg gcaaccaggt caaaatagtt tttcaactga gtcgagatgt
    13201 tgaagttata catcggtgcc gcaataacga taacgtcgtg ggctttcagc tcggcaatca
    13261 actcatcgga aagtgccaga gcttcctgct gacgcggagt cagcggcgca tcgctcggac
    13321 gcagagcgcc aaccagttcg ccatccagta ccggaatcgg atttgcagcc aggtcgcgaa
    13381 cggtgatttc atcagcggag tgcttttcgc gccattgttc aacaaaataa tcggacaact
    13441 gattagactg agagtaccct gccaggatgc tggatttaag aactaatacc ttgctcatgg
    13501 tgtttcctta tagatgtttg aatgggcgat gccccgttgc ttgttgacac tttattcaca
    13561 atcctgccac agagatagcg caataaatcg aagcctatgt tcgaatttat tgaacaacgc
    13621 atagaaagcc gcgatgtggt actctatatc tatcatttaa aagaaaatta atcaggcaga
    13681 ctactgccca ctaacgttat gacagaacaa caaaaattga cctttacggc cttgcagcag
    13741 cggctggatt cgctgatgct gcgtgacaga ctgcgttttt ctcgccgtct gcacggcgtg
    13801 aagaaggtta aaaatcctga tgcacaacag gccattttcc aggagatggc gaaagagatt
    13861 gaccaggcgg cagggaaagt cctgctgcgt gaagcggcac gaccggaaat tacttatcct
    13921 gacaatttac cggttagtca gaaaaaacag gacattctcg aagcgattcg tgatcaccag
    13981 gtggtgatcg tcgccgggga aacgggttct ggtaaaacga ctcagttacc gaaaatctgt
    14041 atggagctgg ggcgcgggat taaaggactg atcggccata cccagccgcg tcgtctggcg
    14101 gcaagaacag tggcgaaccg tattgcggaa gagctgaaaa cggagccggg cggttgcatc
    14161 ggttacaaag tgcgtttcag cgatcacgta agtgataaca cgatggtcaa gctgatgacc
    14221 gacggtatcc tgctggcgga gatccagcaa gaccgcctgc tgatgcagta cgacactatc
    14281 attattgacg aagcgcacga acgcagcctg aatatcgatt ttttgctcgg ctatttgaaa
    14341 gagttgctgc cgcggcgtcc tgacctaaaa atcattatca cttccgcgac tatcgacccg
    14401 gaacgctttt cgcgccactt taataatgcg ccgattattg aagtctccgg tcggacctat
    14461 ccggtggaag tgcgctatcg cccgattgtt gaagaagccg atgacaccga gcgcgatcag
    14521 ttgcaggcga tttttgacgc cgtagacgaa ctgagtcagg aaagccatgg cgacattctg
    14581 atctttatga gcggcgagcg ggaaatccgc gataccgccg atgcgctgaa caagctgaac
    14641 ttacgccata ccgaaatctt gccgctttat gcgcggcttt cgaacagcga acaaaatagg
    14701 gtattccagt cgcacagcgg acggcgcatt gtgctggcga ccaacgtcgc ggaaacgtcg
    14761 ctgaccgtac cggggattaa atacgttatc gaccccggta cagcgcgtat cagccgctac
    14821 agctatcgca ccaaagtgca gcgtttgccg attgagccga tttcccaggc gtctgccaat
    14881 cagcgtaaag gccgctgtgg tcgtgtgtcc gaagggatct gtattcgtct ctattccgaa
    14941 gacgatttcc tctcgcgccc ggagtttacc gatccggaga ttctgcgtac caacctggcc
    15001 tcggttattt tgcagatgac cgcgctgggg ctgggcgata tcgctgcgtt cccgtttgtc
    15061 gaagcaccgg ataaacgcaa tatccaggat ggcgtgcgtc tgctcgaaga gctgggcgcg
    15121 atcaccactg atgaacaggc cagcgcctat aaactgacgc cgctcggtcg ccagctctcg
    15181 cagttgcctg tcgacccacg tctggcgcgt atggtgctgg aagcgcaaaa acatggctgc
    15241 gtgcgtgagg cgatgattat cacgtccgcg ctctccattc aggatccgcg cgaacgtccg
    15301 atggacaaac agcaggcatc ggacgaaaaa catcgtcgct tccacgacaa agagtctgac
    15361 tttctcgcgt ttgtgaatct gtggaattat cttggcgagc agcaaaaggc gctttcttcc
    15421 aacgccttcc gtcgcctgtg tcgtaccgat tatctcaact atctgcgcgt gcgcgaatgg
    15481 caggatatct acacccagtt gcgtcaggtg gtgaaagaac ttggcattcc ggttaacagc
    15541 gaaccggcgg agtatcgcga aattcacatt gcgttgctga ccggtttact ttcccatatc
    15601 ggcatgaaag atgccgataa acaagaatat accggcgcac gtaacgcgcg tttctccatc
    15661 ttccccggtt ctggtttatt caaaaaaccg cctaaatggg taatggtggc ggaactggta
    15721 gaaaccagcc gcctgtgggg gcgcattgct gcgcgtatcg acccggaatg ggtggagcca
    15781 gttgctcagc atttgattaa acgcacctac agcgaaccgc actgggaacg ggcgcagggc
    15841 gcggtgatgg caacggaaaa agtcactgtt tatggtttgc cgattgttgc cgcgcgcaag
    15901 gtcaactaca gccagatcga tccggcgtta tgtcgtgaac tctttattcg ccacgcgctg
    15961 gtggaaggtg actggcagac gcgtcacgca ttcttccgtg aaaacctgaa actacgggcg
    16021 gaagtagaag agctggaaca caaatcacgt cgccgcgata ttctggttga tgacgaaacg
    16081 ttgtttgagt tctacgacca gcgcatcagc cacgatgtaa tctccgctcg ccacttcgac
    16141 agctggtgga aaaaagtcag ccgcgaaacg cctgatttgc tcaactttga aaaaagcatg
    16201 ttgatcaaag agggcgcaga aaaaatcagc aagctggatt acccgaactt ctggcatcag
    16261 ggcaatctca agctgcgttt gagctatcag tttgagcccg gcgcggatgc tgacggtgtg
    16321 accgtacata ttccgctgcc gttacttaac caggttgagg aaagcgggtt tgaatggcag
    16381 atccccggtc tgcgccgcga actggtgatt gctctgatta aatcgttgcc gaaaccggta
    16441 cgccgtaatt ttgtacccgc gccaaactat gccgaagcgt ttttaggccg cgtcaaaccg
    16501 ctggagttac cgttgctcga cagccttgag cgcgagttac ggcggatgac cggcgttacc
    16561 gttgaccgcg aagactggca ctgggatcag gtgcccgatc acctgaaaat taccttccgc
    16621 gtggtggatg acaaaaacaa gaagctaaaa gaagggcgct cgctacaaga tctgaaagat
    16681 gcgctgaaag gcaaagtgca ggaaacgcta tctgcggtgg cggatgacgg tatcgagcag
    16741 agcggcttac atatctggag ttttggtcag ctgccggaaa gctacgaaca gaagcgtggc
    16801 aactacaaag tgaaggcgtg gccggcgctg gtggatgagc gcgacagtgt ggcgatcaaa
    16861 ctgtttgata acccgctgga gcaaaagcag gcaatgtgga acggtcttcg ccgtctactg
    16921 ctgctgaata ttccatcgcc aatcaaatat ttacatgaaa agttaccgaa caaagccaag
    16981 ctgggactgt actttaaccc gtatggcaaa gtgctggagc tgatcgacga ctgtatctcc
    17041 tgcggtgtgg ataaattgat cgacgccaat ggtggcccgg tctggacgga agaaggcttt
    17101 gctgcgctgc atgaaaaagt gcgtgccgaa ctgaacgaca cggtggtgga tattgcgaag
    17161 caggtcgagc aaatccttac ggcagtgttc aatatcaaca aacgtctgaa agggcgggtg
    17221 gatatgacca tggcgctggg gctttctgac attaaagcgc agatgggcgg gttggtatat
    17281 cgcggttttg tcactggtaa cggcttcaaa cggctgggcg acacgctgcg atatttgcag
    17341 gcgattgaaa aacggctgga aaaactggcg gttgatccac atcgcgaccg tgcgcagatg
    17401 ctgaaagtcg aaaacgtcca gcaggcgtgg cagcaatgga tcaacaaact gccgcccgca
    17461 cgtcgtgagg atgaagacgt gaaagagatc cgttggatga tagaagagtt gcgcgttagt
    17521 tacttcgctc aacaacttgg tacgccttat ccgatttcag ataagcgtat tttgcaggcg
    17581 atggagcaga ttagcggtta accctgctat ttgcctgata aagaaaaaac ccggtaagca
    17641 tttagcgccg ggttttttat taattctaaa acggtaaggg taaaaattca ggaattcaga
    17701 aaaatacaat tctctgctgc aagatgaata atgtttatct acagcatttc cttaaaagat
    17761 atgtcaggct tgcggagtgg cggttaagga catacgattt cctcctttca gagtgctccg
    17821 cttctcacta ttatctcacg cagtattctt aagggaacga taaggaggaa ccatgaacat
    17881 taccccgttt ccgacgcttt cgccggcaac tatagatgcc ataaatgtta tcggacagtg
    17941 gctggcgcag gatgatttct ccggtgaggt gccgtatcag gccgattgcg tgatccttgc
    18001 aggcaatgcg gttatgccga ctatcgatgc ggcatgtaag attgcccgcg atcagcaaat
    18061 tcctttactg attagtggtg gtatcggtca ctcgacaact tttttgtata gcgccatcgc
    18121 acagcatccg cactacaaca ctatccgcac cactggcaga gcagaagcga ccatcctggc
    18181 ggatatcgct catcagttct ggcacattcc gcatgaaaaa atctggattg aagaccagtc
    18241 aacaaactgc ggtgaaaacg cacgctttag catcgcgcta ttgaatcagg ccgtagaacg
    18301 agttcatacg gctatcgttg ttcaggaccc caccatgcag cggcgcacga tggcgacgtt
    18361 ccgccgtatg actggggaca atcccgatgc accacgctgg ttaagttatc ccggattcgt
    18421 tcctcagtta ggaaataacg cagacagtgt aatctttatt aatcagttac aaggattatg
    18481 gccagttgag cgttatctct cactactcac tggcgagctg ccgcgtttac gcgatgatag
    18541 cgatggctac ggtccccgcg ggcgagattt tatcgttcac gttgattttc cggcagaagt
    18601 catccatgca tggcaaacgc tgaaacatga tgcggtgctc atcgaggcga tggaaagtcg
    18661 ctcgttacgt taaaaattgc ccgtttgtga accacttgtt tgcaaacggg catgactcct
    18721 gacttttatt tctgcctttt attcctttta cacttgtttt tatgaagccc ttcacagaat
    18781 tgtcctttca cgatgccgtc tctctgatga ttgatgttaa ttaacaatgt attcaccgaa
    18841 aacaaacata taaatcacag gagtcgccca tgtcagtacc cgttcaacat cctatgtata
    18901 tcgatggaca gtttgttacc tggcgtggag acgcatggat tgatgtggta aaccctgcta
    18961 cagaggctgt catttcccgc atacccgatg gtcaggccga ggatgcccgt aaggcaatcg
    19021 atgcagcaga acgtgcacaa ccagaatggg aagcgttgcc tgctattgaa cgcgccagtt
    19081 ggttgcgcaa aatctccgcc gggatccgcg aacgcgccag tgaaatcagt gcgctgattg
    19141 ttgaagaagg gggcaagatc cagcagctgg ctgaagtcga agtggctttt actgccgact
    19201 atatcgatta catggcggag tgggcacggc gttacgaggg cgagattatt caaagcgatc
    19261 gtccaggaga aaatattctt ttgtttaaac gtgcgcttgg tgtgactacc ggcattctgc
    19321 cgtggaactt cccgttcttc ctcattgccc gcaaaatggc tcccgctctt ttgaccggta
    19381 ataccatcgt cattaaacct agtgaattta cgccaaacaa tgcgattgca ttcgccaaaa
    19441 tcgtcgatga aataggcctt ccgcgcggcg tgtttaacct tgtactgggg cgtggtgaaa
    19501 ccgttgggca agaactggcg ggtaacccaa aggtcgcaat ggtcagtatg acaggcagcg
    19561 tctctgcagg tgagaagatc atggcgactg cggcgaaaaa catcaccaaa gtgtgtctgg
    19621 aattgggggg taaagcacca gctatcgtaa tggacgatgc cgatcttgaa ctggcagtca
    19681 aagccatcgt tgattcacgc gtcattaata gtgggcaagt gtgtaactgt gcagaacgtg
    19741 tttatgtaca gaaaggcatt tatgatcagt tcgtcaatcg gctgggtgaa gcgatgcagg
    19801 cggttcaatt tggtaacccc gctgaacgca acgacattgc gatggggccg ttgattaacg
    19861 ccgcggcgct ggaaagggtc gagcaaaaag tggcgcgcgc agtagaagaa ggggcgagag
    19921 tggcgttcgg tggcaaagcg gtagagggga aaggatatta ttatccgccg acattgctgc
    19981 tggatgttcg ccaggaaatg tcgattatgc atgaggaaac ctttggcccg gtgctgccag
    20041 ttgtcgcatt tgacacgctg gaagatgcta tctcaatggc taatgacagt gattacggcc
    20101 tgacctcatc aatctatacc caaaatctga acgtcgcgat gaaagccatt aaagggctga
    20161 agtttggtga aacttacatc aaccgtgaaa acttcgaagc tatgcaaggc ttccacgccg
    20221 gatggcgtaa atccggtatt ggcggcgcag atggtaaaca tggcttgcat gaatatctgc
    20281 agacccaggt ggtttattta cagtcttaat gagtgaaaga ggcggaggtt ttttcctccg
    20341 cctgtgcgcg tcagagttta gcgaattttt cgagggtgcg aataagctgt gtgacgaagc
    20401 catattcgtt atcgtaccag gcgaccgttt tcaccagttg taaatcgccc acggcggtaa
    20461 tttccgtttg cgtggcatca aacaccgaac cgaaatggct gccaatgata tcggaagaga
    20521 ctatttcttc atcggtataa ccaaatgact cgttattggt ggttgcttgt ttaagtgcgt
    20581 tattcacctc ttcggcagtc acttttttcc gagaatcgat accagttcag tgaccgaacc
    20641 tgttttcacc ggcacgcgtt gcgcatgacc tttcagtttg ccgctcagtt ccgggatcac
    20701 cagaccaatg gcttttgccg cccccgtagt gtggggaatg atattttctg ccgctgcgcg
    20761 tgaagcacgt aaatctttac cacgcgggcc atccaccagt gactgggtgc cagtataggc
    20821 atgaatggtc gtcatcgtgc cgacttctat cccgaaactg tcatgcaagg ctttggccat
    20881 cggcgcaaga cagttagtgg tgcatgacgc cacggaaaca atggtgtcgt tgccatccag
    20941 agtgtcgtca ttgacgttat aaacgatagt tttcatttca ccggcagggg cggaaatcaa
    21001 caccttcttc gcaccagcat caagatgcgt ctgcgatttc tcggcggagg tataaaagcc
    21061 agtacattcg acaatgattt ctgcaccttt cgctttccac ggaatatttt tagcctcttt
    21121 ttcggcgtaa accgcgatac ttttcccatc aacgataagt gaatcttccg taaaatcaac
    21181 gctccagggg aatggtccgt agtttgaatc atgtttcagc aggtaggcga gaatttatgg
    21241 ggaagtgaga tcattaatag cgacaacgtc tatgttgctt ttgacttcaa gtaatcgacc
    21301 caacaccagt cgaccgatac gaccaaaacc gttaatacca actttactca tggttttctc
    21361 ctgtcaggaa cgttcggatg aaaattgatc ctttccaggc ttagaccagg atggcgggat
    21421 gggcaatctc cattctcaca gtgaaacgta acgtactgaa aacgggtgaa caatatttaa
    21481 tgaaattttg agaaaagccc gttatgttaa cggaaaatta tgttaaagca ggaaatgtta
    21541 tggaaaataa atattcaagg ttacaaatca gcattcactg gctggtcttt ttactggtta
    21601 tcgcagcgta ttgcgcaatg gagtttcgtg gtttcttccc acgtagcgat cggccactca
    21661 tcaacatgat tcatgtttcc tgtggcatct caattctcgt gctgatggtc gttcgtcttt
    21721 tgttaaggct gaaataccca accccgccga ttatacctaa gccaaaaccg atgatgacgg
    21781 gactggcgca tttgggacat ttggtgattt atctcctgtt tattgcgctg ccagtgattg
    21841 gtttggtgat gatgtataac cggggcaacc cgtggtttgc gtttggtttg acgatgcctt
    21901 acgcttcaga ggccaatttc gaacgggtag atagcttaaa gtcgtggcat gaaacgctgg
    21961 cgaatctggg atattttgtc atcgggttgc acgctgcggc tgcactggca caccactatt
    22021 tctggaagga caacacactt ctacgcatga tgccgcgtaa acgttcctga aggatattta
    22081 aagaaaacgc ctgtactaaa accgacccgt ggtacaggcg aagaatacgg gtctacatcg
    22141 gaagcgccta ttatatttat ttgtatgata aataaaacca taatccttgc ccatacgtcc
    22201 atctggctta tttttaatca attcacccga tctttgatct catcaacggt atcaaaataa
    22261 accagcgtat aacgttcaaa tcgaacataa gattcgataa accatggagg ttatatgaaa
    22321 aaactggcac ttattttgtt tatgggaacg cttgtttcct tttatgccga tgccgggcgc
    22381 aaaccctgtt ctggttcgaa aggggggatc tcacactgta cggcaggcgg caaatttgtc
    22441 tgtaatgatg gttctattag tgcatcgaaa aaaacatgca ctaactgaag tgtaaaaggg
    22501 gtgccatgag aaaatgaatc tgctagtcaa atgcgcgggg aaaatccccg cgcttgccct
    22561 tacctggacg tgcaggccat gagcgcagca acctccttat caccgtcccg gaaccgcagt
    22621 tcgtagagcg tttgtcgggt caggagtgtg aatgtcagaa tcgtaatgca gataatgagc
    22681 agacacacca ccagagggtt gtgcttcata gcctttctcc ttgccggatg gcgggtaaga
    22741 ggctaagatc tgaattgcta ggttcattcg ttggcctcgg ttgatagaaa tatcggtcgg
    22801 ggccttcgtc tttctgattc ccggttagcc tgaaaacaga aagtctcagg cacccgcagg
    22861 catcctatga ggtttcctta gggacgaaaa taatcacttc acgaaattgc gtgctgtttt
    22921 ccagaatttt tcgtcattcg ggttagccag tttagccatt cgttactctc ttcattccaa
    22981 tagcattaat tttctatgca ataattgttg taaaaatgtg acgcaaagag gtttttggtc
    23041 ataagtaatt accgtcaagt gccgatgact ttctatcagg agtaaacctg gacgagagac
    23101 aacggtaatg aatacaactc cctcacagcg attaggtttt ttgcatcaca tcaggttggt
    23161 tccgttattt gcctgcattc taggcggtat cttagttcta ttcgcattaa gttcagccct
    23221 ggctggctat ttcctctggc aggccgatcg cgatcagcgt gatgttactg cggagattga
    23281 gattcggacc gggttagcga acagttcaga ttttttgcgt tcagcccgga tcaatatgat
    23341 tcaggccggg gctgcgagtc gtattgcgga aatggaagca atgaagcgaa atattgcgca
    23401 agccgaatcg gagattaaac agtcgcagca aggttatcgt gcttatcaga atcgaccggt
    23461 gaaaacacct gctgatgaag ccctcgacac tgaattaaat caacgctttc aggcttatat
    23521 cacgggtatg caacctatgt tgaaatatgc caaaaatggc atgtttgaag cgattatcaa
    23581 tcatgaaagt gagcagatcc gaccgctgga taatgcttat accgatattt tgaacaaagc
    23641 cgttaagata cgtagcacca gagccaacca actggcggaa ctggcccatc agcgcacccg
    23701 cctgggtggg atgttcatga ttggcgcgtt tgtgcttgcc ctggtcatga cgctgataac
    23761 atttatggtg ctacgtcgga tcgtcattcg tccactgcaa catgccgcac aacggattga
    23821 aaaaatcgcc agtggcgatc tgacgatgaa tgatgaaccg gcgggtcgta atgaaatcgg
    23881 tcgcttaagt cgtcatttac agcaaatgca gcattcactg gggatgacag tagggactgt
    23941 tcgacagggc gcggaagaga tttatcgtgg caccagcgaa atttcagctg gcaatgcgga
    24001 cctgtcatct cgcaccgaag aacaagcggc ggctatcgaa caaactgccg ccagcatgga
    24061 gcaactcact gcgacggtga aacagaatgc ggataacgcg catcatgcca gcaaactggc
    24121 gcaagaggtt tctattaaag ccagcgatgg cgggcagacg gtttccggtg tagtaaaaac
    24181 gatgggcgct atctccacga gttcgaagaa aatttctgag atcaccgccg tcatcaacag
    24241 tattgctttc cagacgaata ttctggcact gaatgctgcc gttgaagccg cgcgagcggg
    24301 tgagcaaggg cgtggatttg ccgttgtcgc cagcgaagta cggacactcg caagtcgcag
    24361 cgctcaggcg gcgaaagaga ttgaaggctt gatcagtgaa tcagtcaggt taattgacct
    24421 ggggtcggat gaggtggcaa cggccgggaa aaccatgagc actattgttg atgccgtcgc
    24481 gagtgtcaca catatcatgc aggaaatcgc cgccgcctcg gatgaacaaa gtagaggcat
    24541 aacgcaggtt agccaggcga tttctgaaat ggataaggtg acgcaacaga atgcttctct
    24601 ggtagaagag gcctcagcgg cggcggtgtc ccttgaagaa caggcggcac gattaactga
    24661 ggcggtggat gtattccgtc tgcacaaaca ttctgtgtcg gcagaacctc gcggagcggg
    24721 tgaaccagtt agtttcgcta cggtgtgaaa atgttcaagg agggatcgac agatcccttc
    24781 acctttcaga acggcattga ttttcgaata gcgttaatca tcaactggca accagaagag
    24841 aacgtcgcat ctacgcgggt cagtattcca atcggttcgc ctgcaccatg tcccggaaca
    24901 ggcagggcca ccagcgtggc atgacgcagg tcgtctttta cagcgccaga agggacaaac
    24961 cacacgtaat cgtattcaac cgtaagttga cgagatagcg aagcagacag cgtttcgata
    25021 caacccgaag gaattttaca gccctggctc tgcactaatg catctgaatg ctggcgtggc
    25081 gcagtgcctt ctggtgatac aacgaccggc cattccagca cccggcttag cgttacgttc
    25141 tcctgaagta gcgggtgatt agggcggaca accagcttca acgattcaag aaacagcagt
    25201 tcgtaattaa gcccggtcat cagttcagga tctgacatcc gaccaatgcc gatatcgatt
    25261 tccccggttt ttaaacccgc cagaatcata gggttactca ttgtcgcaac ttgcaaggtc
    25321 gtctcttttt gttgctgatg aaactgacct ataaccgaag gtaatatccc cagtgccgca
    25381 gtaggtagtg caccaaccct gacgacatca ttattaagac cttctttacg atgaagcgac
    25441 cgtccggcag tgttgatggc gtcaagaact ctgactgcat gcgttaaaaa ttgttcgccg
    25501 ggtaaggtaa gttgcgcccc ctgacgacca cgctcaaaca agcgagcgcc agtcagctgc
    25561 tccagttcat tcaatgtctt agagagcgca ggttgactca aattaagggt ttcagccgcg
    25621 cgccccaaag ttccttgttg tgcgacagct acgaatgtat gaaggtggcg caaacggatg
    25681 cgctgactaa acagactatt tttttccata agcgatgtta aaaacgaagc ggtgtcgctg
    25741 acaagtgaag ttgtttgatt atgataactt gattgcaaaa tattattaac aattaaagca
    25801 attatgttac agcaaaatgg ataatattga tgttttcgcg gcgagatcac agtttgtaaa
    25861 ttcttcccgc aagagtgaat gcggttacct acactccaga ttactgacca ctggaggcag
    25921 acactatggc gaacagcatc acggcggatg agattcggga acagttttcg caggcaatgt
    25981 cagccatgta ccagcaagaa gttccgcaat atggcacgct gctggaactg gtagctgatg
    26041 tgaatctggc tgtgctggaa aacaatcctc aactgcacga aaaaatggta aatgcagacg
    26101 agctggcgcg actgaatgtt gaacgtcatg gggcgattcg cgttgggact gcacaagagc
    26161 ttgctactct tcggcggatg tttgccatta tggggatgta cccggtgagc tattacgatc
    26221 tctcgcaggc aggggtgccg gtacattcga cagcatttcg gcccattgat gatgcttctc
    26281 tggcgcgtaa tcccttccgc gtttttacct ccttactccg ccttgagctt atcgagaacg
    26341 aaattttgcg ccagaaagcg gcggagattc tgcgtcagcg cgatatcttc accccacgtt
    26401 gtcgacaact gttagaggaa tatgagcagc agggcggttt taacgaaaca caggcacagg
    26461 agtttgtgca ggaagccctg gaaacgtttc gctggcacca gtcagcaacg gtagatgaag
    26521 aaacctatcg cgcattgcac aacgaacatc ggttgattgc tgatgtggtc tgttttcctg
    26581 gatgccatat caaccacctg acgccacgta cgctggatat tgaccgggtg cagtcgatga
    26641 tgcctgaatg cggaattgaa cccaaaattc tcatcgaggg gccgccgcgc cgcgaggtac
    26701 cgattttact acgccagacc agctttaaag cactggaaga gacggtgttg tttgcggggc
    26761 agaaacaggg cacgcatacc gcgcgctttg gtgaaattga gcagcgtggc gtggcattaa
    26821 cgccgaaagg gcgacaactg tatgatgatc ttctgcgtaa cgctggaacc gggcaggata
    26881 atctcactca ccaaatgcat ttacaggaaa ccttccgcac ttttcctgac agtgagtttt
    26941 taatgcgtca gcaagggttg gcatggttcc ggtaccgtct gacgccttcg ggtgaggcgc
    27001 atcgtcaggc gattcatcct ggagacgatc cacagccctt aattgaacgt ggttgggtag
    27061 tggcgcaacc catcacctat gaagatttct tgcccgttag cgcggcgggg atcttccagt
    27121 caaatctggg taatgaaacg cagacacgca gtcacggtaa tgccagtcgc gaagcatttg
    27181 agcaggcgtt gggttgtccg gttttggatg agttccagct ttaccaggaa gcggaagaac
    27241 gcagtaaacg tcgctgtggt ttgctttaaa atctgaccat ccgcctttgc aaaaatttgc
    27301 ctgattttac aaacgaatca ggctcatccc atcgacataa aaaaaatgcc gatttatgca
    27361 tattctctca gttcaacaat tggattatta ataaatattg tctagagtga gcggtcataa
    27421 ataagcactt tcttgccgct gaaaacgacc agcgcgggac cattcacaac accagaagga
    27481 ctcactttca ggtatggatc gtagacgatt tattaaaggt tcaatggcta tggccgccgt
    27541 gtgcggtacc agcggcattg cttctctttt ttctcaggcg gcattcgcgg cagattctga
    27601 tattgccgac gggcaaaccc agcgttttga cttctccatt ctacagtcaa tggcgcacga
    27661 cttagcgcaa acagcgtggc gtggtgcgcc tcgtccgtta cctgacacgc tggcgacaat
    27721 gacgccgcag gcttataaca gtattcaata cgacgccgaa aaatcgctct ggcataacgt
    27781 tgagaaccgt caactagacg ctcagttctt ccatatggga atgggattcc gtcgccgcgt
    27841 tcgtatgttt tctgtagatc cagcaacaca tctggcgcgt gaaattcact ttcgcccgga
    27901 gttgttcaaa tacaacgatg caggtgttga tacaaaacaa ttagaagggc aaagcgatct
    27961 cggctttgcc ggttttcgcg tgtttaaagc ccccgaactg gcgcgccgtg atgtagtatc
    28021 atttctcggc gcgagttatt tccgcgccgt tgatgataca tatcaatacg gtttgtcggc
    28081 ccgcggcctg gcgatcgaca cttacaccga cagtaaagaa gagttccccg actttaccgc
    28141 cttctggttt gatacggtaa aaccgggggc aactaccttt accgtttatg cgttgctcga
    28201 tagcgccagc attactggtg cctataagtt cactatccat tgtgagaaaa gtcaggtgat
    28261 tatggatgtg gaaaatcacc tgtatgcgcg caaagacatt aaacagctgg gcattgcgcc
    28321 gatgaccagt atgttcagct gcggtactaa tgaacgtcgg atgtgcgata caattcatcc
    28381 gcaaattcat gactctgatc gtctgtccat gtggcggggc aacggcgagt ggatttgccg
    28441 tccgctgaat aatccgcaaa aattgcagtt caatgcttac accgacaaca acccgaaagg
    28501 gtttggttta ttgcaactgg atcgtgactt ctcccattat caggacatta tgggctggta
    28561 taacaaacgc ccaagtctgt gggtggaacc gcgtaacaag tggggtaagg gcaccatcgg
    28621 cctgatggaa atcccaacaa cgggcgaaac gctggataac attgtctgct tctggcagcc
    28681 agaaaaagct gtaaaagcag gtgatgagtt tgcattccag tatcgtctgt actggagtgc
    28741 gcaaccgcct gttcattgcc cattagcgcg cgttatggcg acgcgtaccg gcatgggcgg
    28801 tttctcggaa ggttgggcgc caggtgaaca ctatcccgaa aaatgggcgc gtcgttttgc
    28861 cgtcgatttc gttggtggtg atctgaaagc tgccgcgcca aaaggcattg agccggtgat
    28921 tacgctttcc agtggggaag cgaagcaaat cgaaattctc tatattgaac ccatcgatgg
    28981 ttatcgtatt cagtttgact ggtatccgac ttcggactcc actgatccgg tcgatatgcg
    29041 gatgtatcta cgttgtcagg gggacgctat cagtgaaaca tggctgtatc agtatttccc
    29101 gccagcgccg gataaacgtc agtatgttga cgaccgcgtg atgagttaat cgttttttct
    29161 tcggcacctt cttcgggagg tgccgtctgg ttaaacacga tcccgctcgc atttttccct
    29221 aagttaaatg agtaatctga tggtgtgtat ttcagataca ccttgtcagc cactaacagg
    29281 gagtgcgtat gtttccagaa taccgagatt taatatcccg tctgaaaaac gaaaatcctc
    29341 gctttatgtc cttgttcgat aaacacaata aacttgatca tgaaattgcc agaaaggaag
    29401 gttccgacgg tcgagggtac aatgcggaag tggtccgcat gaaaaaacaa aagctacagt
    29461 taaaagatga gatgctcaaa atcctgcagc aggagagcgt caaagaggtg taaactttcc
    29521 taagccgcca gccaggcggc ttttttaaca actgcatgga ttgactggag ataagatgac
    29581 tgaaacgata aaagtaagcg aatcacttga attacatgct gttgcagaaa atcacgtcaa
    29641 acctctttat cagttaatct gtaaaaataa aacctggtta cagcagtcgc taaactggcc
    29701 gcagtttgtt caaagtgaag aggacacgcg aaaaacggtg cagggtaatg tgatgttgca
    29761 tcaacgcggc tatgccaaaa tgttcatgat tttcaaagaa gatgaactta tcggcgttat
    29821 ctcgtttaat cgtattgaac cactgaataa aaccgctgaa ataggctact ggctggacga
    29881 atctcatcag gggcagggga tcatttctca ggcgctgcag gcattgattc atcattacgc
    29941 ccagtctggt gaacttagac gcttcgtgat caaatgtcgg gtggacaatc cgcaaagcaa
    30001 ccaggtcgct ttgcgcaatg gttttatcct tgaaggttgc ctgaaacagg ctgagttcct
    30061 gaatgatgcc tatgatgatg tgaacttata cgcgcgtatt atcgattcac aataaccctg
    30121 ccagcggcgt tcgcgtaatg cgctcctcgc cgttaatgac ttttggacca cggacatgaa
    30181 ccgtgtcgcc atcaaaggct tcaacgacgg cgtggtcggt taactccaca tggttttcaa
    30241 ttatcaccgc acctgtaata cggctctcac cttgtatgac aacgtgctcg tcgagcagaa
    30301 tcggtccgcc acgtaccacg gcatttccgc caaccaagac atgatgtttt aacacacaat
    30361 taccttccac aatggcatat tccgccacct gcgaactgta atgaatcgtc ggaatggcat
    30421 cttcttctat gccagctttc acctgcgcgt gaccgtagac tttagcgcaa tcgcatagcc
    30481 agacattgtt ctcttcatta ccttcaatac tggcaaaatc aaaaacttcg gcgcgatgtt
    30541 caataaaagc ataccggacg acggcatcgc cataaatttg tgcctggtgg acaatacgcg
    30601 aggcgctaac ccttgcgcga tcataaattt ggagcaggag ttgatggtcg ggcgttaagc
    30661 cttgtgcggc gacgatcata gaatgttgat caattaaggc gtgaccaaat attctacatt
    30721 gcccgtaaac taatgagtca tgaatggtga cgctgtcact tatatatgca ccctggctga
    30781 tttcactatt atcgatccag acgttatccg ttgcgtaaac ctctccccac agcacgctgg
    30841 tgccggtgat acgcgtatta ccggaaatca ccgctccgcc gaacgcaata gcattctggt
    30901 cgtaaatcca gcaatttcct tcttgtgcta acaccgtttc gcgatcgatc cagccgccag
    30961 cggttcctgc tatcacatcg ttaaaatcgc taatggcgat aatctgccgt aataacacat
    31021 tttttttagt gccatcttcc tgataactaa aggctcgctg ttcttcactt agacgatatt
    31081 tgcgcatagc gttttcccac aggtgactta ctataaccgt agcaaattct gcggctctgg
    31141 ctatgctcga gaaaattcca
//
LOCUS       DACAOP010000051        31040 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.051, whole genome shotgun sequence.
ACCESSION   DACAOP010000051 DACAOP010000000
VERSION     DACAOP010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31040
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.051"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..988
                     /locus_tag="IT892_002569"
     CDS             <1..988
                     /locus_tag="IT892_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP3135773.1"
                     /translation="CDDRITRRVYLNKDKEVSIKVVYFINNVTVHNNTIEIPQTVNGG
                     YDFSHLSLKGIVIKDEDLSNSNFAGCRLQNAIFQDCNMYKTNFNFAIMEKILFDNCIL
                     DDSNFAQIKMTDGTLNSCSAMHVQFYNATMNRANIKNTFLDYSNFYMAYMAEVNLYKV
                     IAPYINLFRADLSFSKLDLINFEHADLSRVNLNKATLQNINLIDSKLFFTRLTNTFLE
                     MVICTGSNMANVNFNNANLSNCHFNCSVLTKAWMFNIRLYRVNFDEASVQGMGITILR
                     GEENISINSDILVTLQKFFEEDCATHTGMSQTEDNLHAVAMKITADIMQDAD"
     gene            complement(1142..2791)
                     /locus_tag="IT892_002570"
     CDS             complement(1142..2791)
                     /locus_tag="IT892_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HAP3135774.1"
                     /translation="MEIFFTILIMTLVVSLSGVVTRVMPFQIPLPLMQIAIGALLAWP
                     TFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVVVTVVGIGF
                     LIYWVVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
                     VSLKFAVAVAMGTMIFTVGGATVEFMKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEP
                     ATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWA
                     MLEFVFNGMVFLLLGLQLPGILETSLMAAEIDPNVEIWMLFTDIILIYAALMLVRFGW
                     LWTMKKFSNRFLKKKPMEFGSWTTREILIASFAGVRGAITLAGVLSIPLLLPDGNVFP
                     ARYELVFLAAGVILFSLFVGVVMLPILLQHIEVADHSQQLKEERIARAATAEVAIVAI
                     QKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSVQEENLERRFRLAA
                     LRSERAELYHLRATREISNETLQKLLHDLDLLEALLIEENQ"
     gene            complement(2942..4291)
                     /locus_tag="IT892_002571"
     CDS             complement(2942..4291)
                     /locus_tag="IT892_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP3135775.1"
                     /translation="MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVI
                     VVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWANLPLAIGCAISLTAFTAFSLVLG
                     QHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
                     VGLVIKNPLDGLPVALGDFATFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGL
                     IFDPNVHFSGVFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTI
                     RAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVYIESAAGTAAGGKTG
                     LTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGL
                     VTAVFIVLTCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI"
     gene            complement(4837..5301)
                     /gene="soxR"
                     /locus_tag="IT892_002572"
     CDS             complement(4837..5301)
                     /gene="soxR"
                     /locus_tag="IT892_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="HAP3135776.1"
                     /translation="MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSG
                     NQRRYKRDVLRYVAIIKIAQRIGIPLATIGEAFGVLPEGHTLSAKEWKQLSSQWREEL
                     DRRIHTLVTLRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN"
     gene            5387..5710
                     /gene="soxS"
                     /locus_tag="IT892_002573"
     CDS             5387..5710
                     /gene="soxS"
                     /locus_tag="IT892_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide response transcriptional regulator
                     SoxS"
                     /protein_id="HAP3135777.1"
                     /translation="MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRT
                     VTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSD
                     YRHRL"
     gene            complement(5713..7299)
                     /gene="pdeC"
                     /locus_tag="IT892_002574"
     CDS             complement(5713..7299)
                     /gene="pdeC"
                     /locus_tag="IT892_002574"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdeC"
                     /protein_id="HAP3135778.1"
                     /translation="MSHRARHQLLALPGIIFLVLFPIILSLWIAFLWAKSEVNNQLRT
                     FAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDN
                     HFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
                     FWSEVMSDDPTLQWGVYDTVTKTFFSLSKEASAATFSPLIHLKDLTVQRNGYLYATVY
                     STKRPIAAIVATSYQRLITHFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQ
                     RALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQIMNPAEFIPLAEKEGMIEQI
                     TDYVIDNVFRDLGDYLATHADRYVSINLSASDFHTSRLIARINQKTEQYAVRPQQIKF
                     EVTEHAFLDVDKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVE
                     TLTTHKTSHLIAEHIIELAHSLGLKTIAEGVETEEQVNWLRKRGVRYCQGWFFAKAMP
                     PQVFMQWMEQLPARELTRGQ"
     gene            7729..8010
                     /locus_tag="IT892_002575"
     CDS             7729..8010
                     /locus_tag="IT892_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135779.1"
                     /translation="MATLTTGVVLLRWQLLSAVMMFLASTLNIRFRRSDYVGLAVISS
                     GLGVVSACWFAMGLLGITMADITAIWHNIESVMIEEMNQTPPQWPMILT"
     gene            complement(8109..8645)
                     /gene="ssb1"
                     /locus_tag="IT892_002576"
     CDS             complement(8109..8645)
                     /gene="ssb1"
                     /locus_tag="IT892_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SSB1"
                     /protein_id="HAP3135780.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDK
                     ATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGQDRYTTEV
                     VVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSA
                     PAAPSNEPPMDFDDDIPF"
     gene            8899..11721
                     /gene="uvrA"
                     /locus_tag="IT892_002577"
     CDS             8899..11721
                     /gene="uvrA"
                     /locus_tag="IT892_002577"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAP3135781.1"
                     /translation="MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
                     EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLA
                     ESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGA
                     CPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEA
                     PWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSA
                     VREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAG
                     QRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV
                     MYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGV
                     HGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLK
                     DVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHF
                     DKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRC
                     EACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEARE
                     FFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYIL
                     DEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGE
                     ILVSGTPETVAECEASHTARFLKPML"
     gene            complement(11756..12112)
                     /locus_tag="IT892_002578"
     CDS             complement(11756..12112)
                     /locus_tag="IT892_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HAP3135782.1"
                     /translation="MTISELLQYCMAKPGAEQSVHNDWKATQIKVEDVLFAMVKEVEN
                     RPAVSLKTSPELAELLRQQHSDVRPSRHLNKAHWSTVYLDGSLPDSQIYYLVDASYQQ
                     AVNLLPEEKRKLLVQL"
     gene            complement(12116..12532)
                     /locus_tag="IT892_002579"
     CDS             complement(12116..12532)
                     /locus_tag="IT892_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HAP3135783.1"
                     /translation="MWYQKTLTLSAKSRGFHLVTDEILNQLADMPRVNIGLLHLLLQH
                     TSASLTLNENCDPTVRHDMERFFLRTVPDNGNYEHDYEGADDMPSHIKSSMLGTSLVL
                     PVHKGRIQTGTWQGIWLGEHRIHGGSRRIIATLQGE"
     gene            complement(12643..13356)
                     /locus_tag="IT892_002580"
     CDS             complement(12643..13356)
                     /locus_tag="IT892_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B acid phosphatase"
                     /protein_id="HAP3135784.1"
                     /translation="MRKITQAISAVCLLFALNSSAVALASSPSPLNPGTNVARLAEQA
                     PIHWVSVAQIENSLAGRPPMAVGFDIDDTVLFSSPGFWRGKKTFSPESEDYLKNPVFW
                     EKMNNGWDEFSIPKEVARQLIDMHVRRGDAIFFVTGRSPTKTETVSKTLADNFHIPAT
                     NMNPVIFAGDKPGQNTKSQWLQDKNIRIFYGDSDNDITAARDVGARGIRILRASNSTY
                     KPLPQAGAFGEEVIVNSEY"
     gene            13719..14125
                     /locus_tag="IT892_002581"
                     /pseudo
     CDS             13719..14125
                     /locus_tag="IT892_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709865.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14463..15656)
                     /gene="tyrB"
                     /locus_tag="IT892_002582"
     CDS             complement(14463..15656)
                     /gene="tyrB"
                     /locus_tag="IT892_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HAP3135785.1"
                     /translation="MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIP
                     QLQAVAEAEARLNAQPHGASLYLPMEGLNCYRHAIAPLLFGADHPVLKQQRVATIQTL
                     GGSGALKVGADFLKRYFPESGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRF
                     NDLLATLKTLPARSIVLLHPCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGF
                     GAGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVMCEDAEAAGRVLGQL
                     KATVRRNYSSPPNFGAQVVAAVLNDEALKASWLAEVEEMRTRILAMRQELVKVLSTEM
                     PERNFDYLLNQRGMFSYTGLSAAQVDRLREEFGVYLIASGRMCVAGLNTANVQRVAKA
                     FAAVM"
     gene            complement(15909..16988)
                     /gene="alr"
                     /locus_tag="IT892_002583"
     CDS             complement(15909..16988)
                     /gene="alr"
                     /locus_tag="IT892_002583"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAP3135786.1"
                     /translation="MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLE
                     TARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNE
                     EQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHF
                     ARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVS
                     PLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGD
                     GYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERI
                     AEMTKVSAYELITRLTSRVAMKYVD"
     gene            complement(17041..18456)
                     /locus_tag="IT892_002584"
     CDS             complement(17041..18456)
                     /locus_tag="IT892_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase DnaB"
                     /protein_id="HAP3135787.1"
                     /translation="MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLD
                     NERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGG
                     FAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
                     AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKT
                     AGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASL
                     SRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREH
                     GGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQR
                     ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVR
                     LTFNGQWSRFDNYAGPQYDDE"
     gene            18539..19522
                     /locus_tag="IT892_002585"
     CDS             18539..19522
                     /locus_tag="IT892_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HAP3135788.1"
                     /translation="MATRIEFHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFID
                     TYIRSGLYPPPSLPSGLGTEAAGIVSKVGSGVKHIKAGDRVVYAQSALGAYSSVHNII
                     ADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQW
                     AKALGAKLIGTVGTAQKAQSALKAGAWQVINYREEDLVERLKEITGGKKVRVVYDSVG
                     RDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREEL
                     TEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILESRATQGSSLLIP"
     gene            complement(19688..19930)
                     /gene="pspG"
                     /locus_tag="IT892_002586"
     CDS             complement(19688..19930)
                     /gene="pspG"
                     /locus_tag="IT892_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response protein PspG"
                     /protein_id="HAP3135789.1"
                     /translation="MLELLFVIGFFVMLMVTGVSLLGIIAALVVATAIMFLGGMLALM
                     IKLLPWLLLAIAVVWVIKAIKAPKVPKYQRYDRWRY"
     gene            complement(20064..21101)
                     /gene="dusA"
                     /locus_tag="IT892_002587"
     CDS             complement(20064..21101)
                     /gene="dusA"
                     /locus_tag="IT892_002587"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HAP3135790.1"
                     /translation="MHGNSEMQKINQTSAMPEKTDVHWSGRFSVAPMLDWTDRHCRYF
                     LRLLSRNTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAALAQCAKLAEA
                     RGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDD
                     QDSYEFLCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDF
                     PHLTMSINGGIKSLEEAKAHLQHMDGVMVGREAYQNPGILAAVDREIFGSSDTDADPV
                     AVVRAMYPYIERELSQGTYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADINVL
                     EHALKLVADKR"
     gene            complement(21464..22171)
                     /locus_tag="IT892_002588"
     CDS             complement(21464..22171)
                     /locus_tag="IT892_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2713 domain-containing protein"
                     /protein_id="HAP3135791.1"
                     /translation="MWVNKYIDDCTDEDLNDRDFIASVVDRAIFHFAINSICNPGDNK
                     DAMPIEQCTFDVETKNDLPSTVQLFYEESKDNEPLANIHFQAIGSGFLTFVNACQEHD
                     DNSLKLFASLLISLSYSSAYADLSETVYINENNESYLKAQFEKLSQRDMKKYLGEMKR
                     LADGGEMNFDGYLDKMSHLVNEGTLDPDILSKMRDAAPQLISFAKSFDPTSKEEIKIL
                     TDTSKLIYDLFGVKSEK"
     gene            complement(22195..22449)
                     /locus_tag="IT892_002589"
     CDS             complement(22195..22449)
                     /locus_tag="IT892_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135792.1"
                     /translation="MLKIIPGATGYFNKTLNSNQFDNEDAIKDKLDNRGSIKGKLNNI
                     YGKSIDYAALRHRDIIIAKIDLFIQRITHNLWHARKKMCF"
     gene            22767..23282
                     /gene="zur"
                     /locus_tag="IT892_002590"
     CDS             22767..23282
                     /gene="zur"
                     /locus_tag="IT892_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418470.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc uptake transcriptional repressor Zur"
                     /protein_id="HAP3135793.1"
                     /translation="MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISA
                     YDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFI
                     CDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
                     DHSVQVKKKPR"
     gene            complement(23324..23533)
                     /locus_tag="IT892_002591"
     CDS             complement(23324..23533)
                     /locus_tag="IT892_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP3135794.1"
                     /translation="MNKDEAGGNWKQFKGKVKEQWGKLTDDDMTIIEGKRDQLVGKIQ
                     ERYGYQKDQAEKEVVDWETRNEYRW"
     gene            complement(23649..25028)
                     /gene="dinF"
                     /locus_tag="IT892_002592"
     CDS             complement(23649..25028)
                     /gene="dinF"
                     /locus_tag="IT892_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418468.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter DinF"
                     /protein_id="HAP3135795.1"
                     /translation="MPPGVAVCFSSLFIRLVCMAFLTSSDKALWHLALPMIFSNITVP
                     LLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQA
                     LARTLVQPLLLALGAGALIALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPAS
                     LANLVLLGWLLGVQYARAPVILLVVGNILNIVLDVWLVMGLHMNVQGAALATVIAEYA
                     TLLIGLLMVRKILKLRGISGEMLKTAWRGNFRRLLALNRDIMLRSLLLQLCFGAITVL
                     GARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACR
                     QSGIVALLFSVVYLLAGEHIIALLTSLTQIQQLADRYLIWQVILPVVGVWCYLLDGMF
                     IGATRATEMRNSMAVAAAGFALTLLTLPWLGNHALWLALTVFLALRGLSLAAIWRRHW
                     RNGTWFAAT"
     gene            complement(25047..25655)
                     /gene="lexA"
                     /locus_tag="IT892_002593"
     CDS             complement(25047..25655)
                     /gene="lexA"
                     /locus_tag="IT892_002593"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repressor LexA"
                     /protein_id="HAP3135796.1"
                     /translation="MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAE
                     EHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDP
                     SLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
                     QGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL"
     gene            complement(25765..26133)
                     /locus_tag="IT892_002594"
     CDS             complement(25765..26133)
                     /locus_tag="IT892_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP3135797.1"
                     /translation="MANNTTGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVV
                     IACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAV
                     LIAIIVAVITWCILLWSHFG"
     gene            26304..28727
                     /gene="plsB"
                     /locus_tag="IT892_002595"
     CDS             26304..28727
                     /gene="plsB"
                     /locus_tag="IT892_002595"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418465.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsB"
                     /protein_id="HAP3135798.1"
                     /translation="MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYV
                     LPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESI
                     KLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLG
                     RDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFN
                     KLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWN
                     RLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN
                     LNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG
                     RLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLP
                     QMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNI
                     AADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDST
                     VPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMA
                     AIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQ
                     DDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLS
                     VLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLT
                     IESATQGEG"
     gene            complement(28882..29754)
                     /gene="ubiA"
                     /locus_tag="IT892_002596"
     CDS             complement(28882..29754)
                     /gene="ubiA"
                     /locus_tag="IT892_002596"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HAP3135799.1"
                     /translation="MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVP
                     QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVV
                     LVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
                     VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIL
                     QIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVG
                     LVLFLGLAMSYWHF"
     gene            complement(29767..30264)
                     /gene="ubiC"
                     /locus_tag="IT892_002597"
     CDS             complement(29767..30264)
                     /gene="ubiC"
                     /locus_tag="IT892_002597"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418463.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HAP3135800.1"
                     /translation="MSHPALTQLRALRYCKEIPALDPQLLDWLLLEDSMTKRFEQQGK
                     TVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSG
                     PELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLP
                     ASPLY"
     gene            complement(30487..>31040)
                     /locus_tag="IT892_002598"
     CDS             complement(30487..>31040)
                     /locus_tag="IT892_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SopA family protein"
                     /protein_id="HAP3135801.1"
                     /translation="NKFDDFMRQHRFSEVNFDTQQMIDFINRFNTNKWLIDKNNNFFI
                     QLIDQALRSTDDMIKANVWHLYKEWIRSDDVSPIFIETEDNLRTFNTNELTRNDNIFI
                     LFSSVDDGPVMVVSSQRLHDMLNPTKDTNWNSTYIYKSRHEMLPVNLTQETLFSSKSH
                     GKYALFPIFTASWRAHRIMNKGV"
BASE COUNT         8162 a         8009 c         7391 g         7478 t
ORIGIN      
        1 atgtgacgat agaattacga gaagagttta ccttaataaa gataaggaag tgtcaattaa
       61 ggtggtatat tttataaata atgtcaccgt ccataataat actatcgaaa tcccacagac
      121 agtaaatggt ggttacgatt tttcacacct tagcctgaaa ggtatcgtga ttaaagatga
      181 agatttatcc aattcgaatt ttgcaggttg cagactacaa aacgctattt ttcaggactg
      241 taatatgtat aaaacgaatt ttaatttcgc cataatggaa aaaatacttt ttgataattg
      301 tattctcgat gactcaaatt tcgctcagat aaaaatgact gacggaactc taaattcatg
      361 ttccgctatg catgttcaat tctacaatgc aacaatgaat agagccaata ttaaaaatac
      421 cttccttgat tattcaaatt tttatatggc atacatggct gaggtaaatc tttataaagt
      481 aatagcgcca tatattaatt tatttagagc cgaccttagc ttctctaaac ttgatttaat
      541 taactttgaa catgctgatc tgtctcgtgt caacctgaat aaagcaaccc tccagaatat
      601 aaacttaatt gatagcaaac tcttttttac gcggttaaca aatacgttcc tcgaaatggt
      661 tatatgtacc ggctctaata tggctaatgt taattttaat aatgccaatt taagcaattg
      721 ccatttcaac tgttctgttt taacaaaagc ctggatgttt aatatccgtc tctatcgtgt
      781 taatttcgat gaggctagcg tccagggaat gggtattacc attctccgtg gtgaggaaaa
      841 tatctccatt aatagtgata tcctggtaac actacagaaa ttctttgaag aagattgtgc
      901 cactcatact ggcatgtcac aaactgagga taatcttcat gcagtcgcta tgaagattac
      961 tgcagatatt atgcaagatg cagattgagg ttaagtcgaa gaacagccaa tgaattgact
     1021 ttaaaagaga gataacttat ttgttttaga atcatgaatg ttagcccgag ctaacctgtt
     1081 aaaggtgcaa aagattgcac ctttttcaga ttacctcggg cctggttacg tcgctttcgg
     1141 cttactgatt ttcctcaatt agcaacgctt caagcaaatc gagatcgtgc agtaattttt
     1201 gcagcgtttc gttgctgatc tcccgtgtgg cgcgcaggtg gtaaagttca gcacgttcag
     1261 aacgcaatgc cgccagacgg aagcgacgct caaggttctc ttcctgcacg gaactttcaa
     1321 cgtcgttacg tccatcggcg cgacgacgca ggttaccaat gacgcgagaa ctgacctccg
     1381 taagcagctg gttatcgata ttctcttcgg tatccgccgc cagacgctcc tccattttct
     1441 ggatcgccac aatcgccact tctgccgttg ccgctcgcgc aatacgttcc tctttcaatt
     1501 gttgcgaatg atccgcgact tcaatgtgtt gtagcagaat aggcaacatc accacgccga
     1561 caaacagcga gaagagaatg acgccagccg ccaggaacac cagctcatag cgcgccggga
     1621 agacgttacc atccggcaag agcagcggga tagagagcac accggccaga gtgatcgccc
     1681 cacgcacccc ggcgaaagac gcgatcagga tttctcgtgt ggtccacgaa ccaaactcca
     1741 tcggcttctt cttcaggaag cggttgctga actttttcat cgtccacagc cagccgaaac
     1801 ggaccagcat cagcgccgca tatatcagaa taatatcggt aaacagcatc cagatttcga
     1861 cgttagggtc gatttctgct gccatcagcg acgtctccag aatacccggc agctgcagac
     1921 ctaacagcag gaacaccatg ccgttaaaga caaattccag catcgcccag gtgctgtttg
     1981 cacgcaggcg cattgccagc ggcgcacggc gcatcacacc ggagcgggtg atggtcatcc
     2041 cggcggcaac cgcagcgagg atgccggaaa cgccaatatg ttcggcaatc agataagaag
     2101 cgaatggcag caggaacagc aggacgatct gcgtcgcggg ttcatcaccg ccccagcggc
     2161 tgaggaatcg cagcgagcga ccgtacagcc agctcaccac aaaaccggcg agaataccgc
     2221 caatggctac tttcataaat tcgaccgtcg caccgccgac ggtgaagatc atcgtcccca
     2281 tcgccactgc tacggcaaac ttcaacgaca ccagaccgga ggcgtcattc atcaacgctt
     2341 cgccctgcaa aatgcccatg atttttttcg ggatgcgccc ttcgccaaca atcccggaga
     2401 gcgccacagc atcggtcgga gaaagcaccg ccgccagcgc aaaggcaggg atcagcggaa
     2461 tgcccggcac cacccagtaa ataaggaagc caatgccgac cacggtgacc accaccagcg
     2521 ccagcgcgag gccgaaaatc tctcgaccat gttcgagaaa ttcacgggtc ggcgttttcc
     2581 agccgtcagc gaacagcaac ggcgggataa acaagactaa aaagagttca ggatcaaact
     2641 ccacatgcaa accaaacgtc ggccacgcca gtagcgcacc gatggcgatt tgcataagcg
     2701 gaagcgggat ctgaaagggc atgacacgag tgaccacccc ggacagcgag accacgaggg
     2761 tcattatcag tatggtgaag aagatttcca tgcgttccct gtttgcgatg ttttttatga
     2821 tctgagaaag acgttatgcc tgaattctca ttttttcaga atatcgcaaa agctcacaca
     2881 atgtgcggag aaaataaaaa cgggcagcca ttgccacccg ttttcagaat ccgatgaaag
     2941 attagatagc ccagccaccc gcatagaagg tcaccagcgc cacggcgata acgaccgtac
     3001 cgatgttcaa cttgcgccat tcgccggaaa ccagacgacc aatcaccaga gtcgcgaagc
     3061 cgatcatgat gcctgttacg atgttacagg tcagcacgat gaatacagcc gtaaccagac
     3121 ccgccatcgc atcaacaaaa tcagcaaagt cgattttcgc cacgttgctc agcatcagca
     3181 ggccaacgta catcagcgcc ggagccgttg cataccccgg aacgaggtaa gagagcggag
     3241 agaggaacag aatcaggagg aacagcacgc caacggtgat agccgtcaaa ccggttttac
     3301 cgcccgccgc cgtacccgcc gcagactcga tgtataccgc tgccggagcc gcacccacca
     3361 ggccagagaa aacgctgctc atggagtcag tggtcagtgc tttcccaccg tcgatgatct
     3421 gcccatcttt atccagcagg ttcgcctggc cggcgacggc acggatagtt ccggtggcat
     3481 caaatactgc cgtcatcacc agcgccagaa cgcttggcag gactacagga ttcagcgcgc
     3541 ccataatgtc caggctgcca atcagtgaat tgccgttttc atcgctcaat gaaggcatgg
     3601 cgaaaacgcc ggagaaatgg acgttaggat cgaagatcaa accgacaatt gagataccga
     3661 taatggtcag cagaatgcca ccagggactt tcagtttttc caggccgatg atcaccgcca
     3721 gacctaccag tgacataatc accgggaagg tcgcgaaatc acccagcgca acgggcagac
     3781 catcaagcgg gtttttaatc accagaccga caccgttagc ggcaatgagc agcaggaaca
     3841 gaccgatacc aatccccgtg ccgtgcgcca caccgtgagg caagttgcgc aaaatccagc
     3901 tacggatacc cgtggcagaa attaccgtaa acagcacacc catcaggaac acggcaccca
     3961 gcgcgacagg tacgctaata tgttgcccca gcaccaggct gaatgcggta aacgctgtca
     4021 gggagatggc gcaaccaatc gccaacggca gattagccca cagacccatc acgatagaac
     4081 cgagtccggc aaccagacag gttgcaacga aaactgccgc aggcgggaag cctgctttac
     4141 ccaacatacc tggaacgacg atgaccgagt agaccatcgc cagaaacgtt gttaacccgg
     4201 caaccacttc ctgacggaca gtgcttccac gttgtgaaat tttaaaccag gcgtcgagtg
     4261 aaccgccggt acgcgctgat ggcgtagaca taagaaaaca tcccctgaga gtttaatttt
     4321 cgtcaagatg cgtggcggac aatcccctgc cagcgaaacg ttatcttcct gctccaggtt
     4381 tgcgacaatt tgctgcgtcg caaaaaagca aacgtttagc tccgcgcata caaaacgggt
     4441 ggtaaaaaaa gcaaacgatt atccggcgat catagcggct ttttcaaccg aagtttgctg
     4501 cttttttctc ttttattgtc ttgacgatga aaaaccaggc aattgatgcg caaacgttat
     4561 cgtcggtgcg caagattgca gcgttatcga gccgtatacc gttcaggatt gcgataaaaa
     4621 atcgtctgag atgacaaaaa tattgcggtt aaaaagtata cttttacact ggcgaagaaa
     4681 cgtcggtgac atacaattaa agcatcaaca ccaaccggaa cctccaccac gtgctcgaat
     4741 gaggtgtgtt gacgtcgggg gaaaccctcc tgtgtaccag cgggatagag agaaagacaa
     4801 agaccggaaa acaaactaaa gcgcccttgt ggcgctttag ttttgttcat cttccagcaa
     4861 gcgtgcgccg gtaccttctt ctcctaagcg gtcgcccggg ttacgcaacg ggcaatcact
     4921 gcgcgaaagg cagccacaac caatacatcc gtccagttcg tcacgcagcg tcactaaggt
     4981 atgaatgcgc cgatccaact cttctcgcca ttgggacgaa agctgtttcc actctttcgc
     5041 acttaacgta tgcccttcgg gcaacacgcc aaacgcttca ccaatggtcg ccagcggaat
     5101 gccaatacgc tgagcaattt tgataattgc aacatatcgc aacacatcac gtttatatcg
     5161 ccgctgattg ccgctgttac ggatactggt aatcaaccct ttactttcat agaaatgcag
     5221 cgccgatacc gccacaccgc tgcgtttcgc cacttcgccg ggggttagca gcgctttaat
     5281 gcggggtaat ttcttttcca taaatcgctt tacctcaagt taacttgagg aattatactc
     5341 cccaacagat gaattaacga actgaacact gaaaagaggc agatttatgt cccatcagaa
     5401 aattattcag gatcttatcg catggattga cgagcatatt gaccagccgc ttaacattga
     5461 tgtagtcgca aaaaaatcag gctattcaaa gtggtacttg caacgaatgt tccgcacggt
     5521 gacgcatcag acgcttggcg attacattcg ccaacgccgc ctgttactgg ccgccgttga
     5581 gttgcgcacc accgagcgtc cgatttttga tatcgcaatg gacctgggtt atgtctcgca
     5641 gcagaccttc tcccgcgttt tccgtcggca gtttgatcgc actcccagcg attatcgcca
     5701 ccgcctgtaa ttttattgcc cgcgcgttaa ctcccgcgcg ggtaattgct ccatccattg
     5761 cataaacacc tgcggcggca tcgccttcgc aaagaaccat ccctggcaat agcgcacgcc
     5821 gcgtttgcgc agccagttaa cctgctcctc agtttcgacg ccttcagcga tcgtttttaa
     5881 ccccaggctg tgcgccagct cgatgatgtg ttccgcaatc aaatgactgg ttttgtgggt
     5941 ggtcagcgtt tcaacaaacg atttgtcgat tttcaaaata tcgacattca atgatttaag
     6001 gttatgcaag ttagagtagc caataccaaa atcatcaatt gccacttcgt aacctgcctg
     6061 gcggaaagcc agaataatcg gcgtcatttt gtcaacatca agaaatgcat gctcagtcac
     6121 ttcaaattta atttgctgcg gacgcaccgc gtattgctct gttttctgat tgattcgcgc
     6181 tatcaaccgt gacgtatgaa aatcggaggc cgacaggtta atagaaacat agcgatctgc
     6241 atgtgttgcc aggtaatcgc ccagatcgcg gaagacatta tcaataacat aatcagttat
     6301 ctgttctatc atcccctcct tttctgccag cggaataaac tctgccggat tcattatttg
     6361 cccctgctca ccaggccaac gtaacaacgc ttcagcgccg atacattttt ctgttttgat
     6421 atcgattatt ggctggtaat aaagacaaag ttgatgtttt tcgagggcgc gttgcaattt
     6481 acgtttggga gataaatagt tttgtcgaat acgtagccag agtaatagca gaacaagact
     6541 ccccaaaata ccggcgggca acgcaaaaat aagatgatta taaaaatggg ttataagacg
     6601 ttgatatgaa gtcgcaacaa tggctgcaat tgggcgtttt gtcgaataaa ctgtcgcata
     6661 taaatagcca tttctttgta cggttaaatc cttcaaatga atcagcggag aaaacgttgc
     6721 tgccgaggcc tctttgctta acgagaaaaa ggttttcgtc accgtatcat acacacccca
     6781 ttgcaatgtc gggtcatcag acatcacttc actccagaag agagggttga taaccgccac
     6841 ataatttccc cgctgcatat aggtcatttt atagccagag aaaaaaggcg tatcgcggta
     6901 ataatagata gaaacgttag gttcacgctt ataatcggcc ggtgcaatcg tatagccgtt
     6961 tacaggcgct atcagcgatg agcataaaaa atggttatca cgggcataga tcaattcatt
     7021 aatataaaga tagccacgaa taatattcaa cattcgcttt tgatgggctg gagtgcaaac
     7081 ttgcccctga tagcgttcag ctgcatcgct cactaaatct gcctggcgaa tgaccagctc
     7141 ggatttatcc agtgccagtt gagcaaaggt tcggagctga ttattcactt ctgattttgc
     7201 ccaaaggaag gcaatccata gcgaaagaat gatgggaaag agaactaaaa agataatacc
     7261 cggcaacgcc agtaattggt gtcgtgcacg atgactcatt gctatcaatt tcctgcctgt
     7321 ttatacccgg ccattgcaag gtgaaaaccc tgggtaccga cgtctttaga taaatcttac
     7381 ggtataaata gcacttttgc ctgatttgaa attgatacct ttctaatcgt cacctggatg
     7441 aaaataattc attgatattc aaaattaatt tcctacagga atgcagaggc ggcgggaaga
     7501 tatgccctta atgccactga aaaaccacat aatctgtaca gcaataaaag tcacggccta
     7561 atatggctaa caaacaatca attgtgatat agttcacaaa attaatgaaa caaacagagt
     7621 gtttcatttt tgtgttctgc aagccccgcg atagccagag tgtaccacgc ctcccgtgaa
     7681 caacgccgcg ctgtccaggg catcggctct tttcagagga attgtttgat ggctaccctc
     7741 accactggcg tggttcttct tcgctggcaa cttcttagtg ccgtaatgat gtttctggcc
     7801 agcacactca acatccgttt tcgtcggtct gattatgtcg ggcttgcggt gatcagcagc
     7861 ggtctgggcg ttgtttccgc ctgttggttc gcaatggggt tgcttggcat cacaatggcg
     7921 gacatcaccg ctatctggca caacatcgag tcggtgatga tagaagagat gaatcagaca
     7981 ccgccacaat ggccaatgat tttgacctga tacgtagaag cctccataac ggaggcttct
     8041 tttttatggc tggcagatgc tttaatcatc caccttaaaa caatataacc tattgtttta
     8101 atgacaaatc agaacggaat gtcatcatca aagtccatcg gcggctcgtt agacggcgct
     8161 gccggagcgg actgctgcgg gcgagactgc gcgccgccgc tgaactgatt gccaccctgc
     8221 ggctgctgag gctgacccca accgccctgc ggctgaccac caccgatatt gccacctgcc
     8281 ggagcgccac caccctgacg accacccagc atctgcatgg tgccgccaac gttcaccacg
     8341 acttctgtgg tgtagcgatc ctgaccggat tgatcggtcc atttacgggt acgcagctga
     8401 ccttcgatat aaacctgaga acctttacgc agatattcgc tcgccacttc tgccagtttg
     8461 ccgaacagca caacgcggtg ccattcagtc tgttctttca tctcgccggt cgctttatca
     8521 cgccaggatt cggaagtagc cagcgtaatg ttggcaactg cgccaccatt tggcatgtag
     8581 cgtacttccg ggtcctgacc cagattacca acgagaataa ccttgtttac gcctctgctg
     8641 gccatgttcg tgtctcctga aaaaaatcgt tctgaataag tgtaaacgcg cgattgtacc
     8701 attaccaata gcgcttttac tatgttgtga cctcggttcc gggaaacaaa cctggccaga
     8761 cattgttaca caacactccg ggtaatgcat tccaatactg tatattcatt caggtcaatt
     8821 tgtgtcataa ttaaccgttt gtgatcgccg gtagcaccat gccaccgggc aaaaaagcgt
     8881 ttaatccggg aaaggtgaat ggataagatc gaagttcggg gcgcccgcac ccataatctc
     8941 aaaaacatca acctcgttat cccccgcgac aagctcattg tcgtgaccgg gctttcgggt
     9001 tctggcaaat cctcgctcgc tttcgacacc ttatatgccg aagggcagcg ccgttacgtt
     9061 gaatcccttt ccgcctacgc gcggcagttt ctgtcactga tggaaaagcc ggacgtcgat
     9121 catattgagg ggctttctcc tgccatctca attgagcaga aatcgacgtc tcataacccg
     9181 cgttctacgg tggggacaat caccgaaatc cacgactatt tgcgtttgtt attcgcccgc
     9241 gttggcgagc cgcgctgtcc ggaccacgac gtcccgctgg cggcgcaaac cgtcagccag
     9301 atggtggata acgtgctgtc gcagccggaa ggcaagcgtc tgatgctact cgcgccaatc
     9361 attaaagagc gcaaaggcga acacaccaaa acgctggaga acctggcaag ccagggctac
     9421 atccgtgctc gtattgatgg cgaagtctgc gatctttccg atccgccaaa actggaactg
     9481 caaaagaaac ataccattga agtggtggtt gatcgcttca aggtgcgtga cgatcttacc
     9541 caacgtcttg ccgagtcatt tgaaaccgcg ctggagcttt ccggtggtac cgcggtagtg
     9601 gcggatatgg acgacccgaa agcggaagag ctgctgttct ccgccaactt cgcctgccca
     9661 atttgcggct acagtatgcg tgaactggag ccgcgactgt tttcgtttaa caacccggcg
     9721 ggggcctgcc cgacctgcga cggccttggc gtacagcaat atttcgatcc tgatcgagtg
     9781 atccagaatc cggaactgtc gctggctggt ggtgcgatcc gtggctggga tcgccgcaac
     9841 ttctattatt tccagatgct gaaatcgctg gcagatcact ataagttcga cgtcgaagcg
     9901 ccgtggggca gcctgagcgc gaacgtgcat aaagtggtgt tgtacggttc tggcaaagaa
     9961 aacattgaat tcaaatacat gaacgatcgt ggcgatacct ccattcgtcg tcatccgttc
    10021 gaaggcgtgc tgcataatat ggagcgccgc tataaagaga cggaatccag cgcggtacgc
    10081 gaagaattag ccaagtttat cagtaatcgt ccgtgcgcca gctgcgaagg gacgcgtctg
    10141 cgtcgggaag cgcgccacgt gtatgtcgag aatacgccgc tgcctgctat ctccgacatg
    10201 agcattggtc atgcgatgga attcttcaac aatctcaaac tcgcaggtca gcgggcgaag
    10261 attgcagaaa aaatccttaa agagatcggc gatcgtctga aattcctcgt taacgtcggc
    10321 ctgaattacc tgacgctttc ccgctcggca gaaacgcttt ctggcggtga agcacagcgt
    10381 atccgtctgg cgagccagat tggtgcgggc ctggttggcg ttatgtacgt gctggacgag
    10441 ccgtctatcg gcctgcacca gcgtgataac gagcgcctgt tgggtacgct tatccatctg
    10501 cgcgatctcg gtaataccgt gattgtggtg gagcacgacg aagacgcaat tcgcgccgct
    10561 gaccatgtga tcgacattgg cccgggcgca ggtgttcacg gcggtgaagt ggtcgcagaa
    10621 ggtccgctgg aagcgattat ggcggtgccg gagtcgttga ccgggcagta catgagcggc
    10681 aaacgcaaga ttgaagtgcc gaagaaacgc gttccggcga atccggaaaa agtgctgaag
    10741 ctgacaggcg cacgcggcaa caacctgaag gacgtgacgc tgacgctgcc ggtgggtctg
    10801 tttacctgca tcaccggggt ttcaggttcc ggtaaatcga cgctgattaa cgacacactg
    10861 ttcccgattg cccaacgcca gttgaatggg gcgaccatcg ccgaaccagc accgtatcgc
    10921 gatattcagg ggctggagca tttcgataaa gtgatcgata tcgaccaaag cccaattggt
    10981 cgtactccac gttctaaccc ggcgacctat accggcgtgt ttacgcctgt gcgcgaactg
    11041 tttgcgggcg taccggaatc ccgtgcgcgc ggctatacgc cgggacgttt cagctttaac
    11101 gttcgtggcg gacgctgcga ggcctgtcag ggcgatggcg tgatcaaagt ggagatgcac
    11161 ttcctgccgg atatctacgt gccgtgcgac cagtgcaaag gtaaacgcta taaccgtgaa
    11221 acgctggaga ttaagtacaa aggcaaaacc atccacgaag tgctggatat gaccatcgaa
    11281 gaggcgcgtg agttctttga tgccgtacct gcactggcgc gtaagctgca aacgttgatg
    11341 gacgttggcc tgacgtacat tcgactgggg cagtccgcaa ccaccctttc aggcggtgaa
    11401 gcccagcgcg tgaagctggc gcgtgaactg tcaaaacgcg gcaccgggca gacgctgtat
    11461 attctcgacg agccgaccac cggtctgcac ttcgccgata ttcagcaact gctcgacgta
    11521 ctgcataaac tgcgcgatca gggcaacacc attgtggtga ttgagcacaa tctcgacgtg
    11581 atcaaaaccg ctgactggat tgtcgacctg ggaccagaag gcggcagtgg tggcggcgag
    11641 atcctcgtct ccggtacgcc agaaaccgtc gcggagtgcg aagcatcaca cacggcacgc
    11701 ttccttaagc cgatgctgta atcgttaagg ccgctttctg agcggccttt tcctttcaga
    11761 gttgcaccag caatttacgt ttttcttccg gcagtaaatt caccgcctgc tgataagacg
    11821 catccaccag ataatagatt tgcgaatctg gcagcgaacc gtcgagatac acggtgctcc
    11881 agtgcgcttt attcagatgg cggcttggac gcacatcgct gtgctgctga cgtagcagct
    11941 ccgccagctc cgggctggtt ttcagcgaaa cagctgggcg attttctact tctttcacca
    12001 tcgcaaacag tacatcttcc actttgatct gcgtcgcttt ccagtcatta tgcacgctct
    12061 gttctgcgcc tggttttgcc atgcaatatt gtagcaactc cgaaatggtc attttttact
    12121 ccccttgtag tgtcgcgatg atgcgacgcg atccgccgtg gatgcgatgt tcccccagcc
    12181 aaatgccttg ccaggtgccg gtctgaatac gccctttatg caccggcaat acaagcgatg
    12241 ttcccagcat tgaggatttg atatgagaag gcatatcgtc tgctccctca tagtcatgct
    12301 cataatttcc gttgtcggga acggtgcgga ggaaaaaacg ctccatgtcg tggcgtacgg
    12361 tgggatcgca gttctcatta agtgtcagag aggcggaggt atgttgcagc aacagatgca
    12421 gtaagccgat gttaacgcgc ggcatatcag ccagctgatt cagaatttca tccgttacca
    12481 gatgaaaccc acgagatttg gcgctaagcg tgagcgtctt ttgataccac atgtgctgct
    12541 ccttgataaa actctcttaa tcagtttgca gcaagacagc gaaaggataa aggtgtgatt
    12601 aaaaaaacag cattcgggag agcatcacgc tctcccgctc tgtcagtatt ctgaattgac
    12661 gatcacctct tcaccaaacg cacccgcttg tggcaagggt ttgtaggtag agttggaggc
    12721 gcgcagaatg cggataccac gagcgccgac atcgcgtgcg gcggtaatat cattatcaga
    12781 atcgccataa aaaattcgga tatttttatc ctgcagccat tgcgattttg tattttgccc
    12841 tggtttatcg cccgcaaaga tcaccggatt catgttggtg gcaggaatat gaaaattatc
    12901 cgccagcgtt tttgaaaccg tttctgtttt cgtcgggcta cgaccagtca caaagaagat
    12961 cgcgtcaccg cggcgtacat gcatatcaat cagctggcga gcgacctctt ttggaatgct
    13021 gaattcatcc cagccattgt tcattttttc ccagaacaca ggatttttca gataatcttc
    13081 gctttctggc gagaaggttt ttttgccgcg ccagaagccc ggactggaaa aaagtaccgt
    13141 gtcatcgata tcaaacccca ccgccattgg cggacgccct gcgaggctat tttcaatttg
    13201 tgcgaccgaa acccaatgaa tgggtgcctg ttcagcaagc ctggcaacgt tagtcccagg
    13261 gttaagcggt gaaggagatg aggccagggc aacagcggaa ctgtttagag cgaacaataa
    13321 gcaaacggca ctgattgcct gtgtgatctt gcgcatattt ttccctaaat agtcagtatg
    13381 ttgaaacttt ttattgtgag atttgttgca aaaaccatct gaccataacg ccagctgccg
    13441 gggaaaggaa ggattatctg cggtttttgt gatgaaaagc aggatgatta tatttaaccc
    13501 agtaaatacg ttcctgtctt tttttgtata aaaaatgttt attactcgat gtaaggatac
    13561 attaatttta cgtttattat gatgaatcct cggcaaatga gcgaaatttg atagaacatt
    13621 tatctgctgt acgatttaat gaacttaatg atacagcatt acaaaaacaa tcgaagttta
    13681 taaagatgat ttctgattga ccagccccct accctacaat ggtgattaat tttattactc
    13741 gcgatggaga tgatgatatg aatatatcat atgtgaatag caacaaaacg acatctttac
    13801 ctgttgagct agatgcacta aataataaag atatctctta tgccaaagat ttctttttat
    13861 acatagaaac acagttaaaa attgcaaaag attttttaga cctggagaag aagtatcaag
    13921 ttctattgca agtaaagttt ttcacgcatt tattgattta gttaacaaaa tcaggggtaa
    13981 gaaagacttt atgtatattt gcacgctttg ctgttttgcc gaggaggtta aaggtgatta
    14041 ttctcattac aggacctttt tatttgatat tggtaatcaa tataaggtta aacttacaca
    14101 aagcggaaaa aagagttctc tttaacatta gaatttaacg atactataat tgaatctcag
    14161 aaagtcacag gcaataaggc aaagcatatt cttgaggata tagaaatatt ctatcgtaac
    14221 aaacccgata cttattatta aatttaataa tggttagatg tgcagaaatt attactccac
    14281 ccaaaaaaac aggataagga attccagata attgggataa gcttaacaat aaaagaacta
    14341 acaacgttta ttatctctca cgtagaacga tggcatcaaa aaaatcatct ataaagaaag
    14401 agtgaaagcg acgacagttt aatttcactg caggctgggt agctccagcc tgctttcctg
    14461 cattacatca ccgcagcaaa cgcctttgcc acacgttgta catttgccgt atttaacccg
    14521 gcgacacaca tgcgaccgct ggcgatgaga tagacaccaa attcttcacg tagtcggtca
    14581 acctgagcgg cacttaaacc ggtataactg aacatgccgc gctgattaag cagataatcg
    14641 aaattgcgtt ctggcatctc tgtgcttaat accttcacca attcctgacg cattgccaga
    14701 atgcgagtac gcatctcttc tacttccgcc agccagctgg ctttcaatgc ctcgtcattc
    14761 agcactgcag ccaccacctg cgcaccaaaa ttcggcgggc tggagtagtt gcggcgaact
    14821 gttgctttca attgccccag tacgcggcca gcggcttcgg catcttcaca cataacagaa
    14881 agtccgccga cgcgctcgcc gtaaagggag aaaattttcg agaacgaatt gctcaccaga
    14941 gcgggtaatc cagcgctggc aatggcgcga atagcgtagg catcctcttc cataccggca
    15001 ccaaatcctt gataggcaat atcgaggaat ggaataagct cgcgggcttt gagaatttca
    15061 atcaccgcat cccactgatc attagtgaga tcggcacccg ttgggttgtg gcaacatgga
    15121 tgcagcaaca caatactgcg ggcaggtaat gttttcagcg tcgccaacag gtcattaaag
    15181 cgcacgccgt tagtcgcttc gtcataccag gggtaagtac tcacttcgaa tccagccccg
    15241 gcgaatattg ctacgtggtt ttcccaggta ggatcgctga cccagacgcc tgattccggg
    15301 aagtagcgtt tcaggaaatc cgcgcccact ttcaatgccc cggagccgcc aagggtttga
    15361 atggttgcta cgcgctgttg tttcagtacc ggatggtccg caccaaacag cagcggcgca
    15421 atggcatggc gatagcagtt aagcccttcc atcggtaaat aaagcgaagc gccatgaggc
    15481 tgcgcattca ggcgcgcttc cgcctccgcc acggcttgca gttgtggaat aattccgtct
    15541 tcgttgtagt acagaccgat acttaaattc actttgtcgc tgcgagggtc ttctttaaaa
    15601 cgctccataa gcgtaagaat cgggtcgcca gcgtaggcgt caactttttg aaacacgcga
    15661 tggttctcca ggtttacggg caggtggtta aaacacaata aaccggaaga aggcgaagat
    15721 cgagtggatg ttcaggagcg aacggcaatt agcaacagag tgagactcat gacaaacgta
    15781 catccgccag aggcacgacc tttataagag catgaaagaa catcaactta ttgaattttt
    15841 aggattttat tggccggata aggcattcac gccgcatccg gcacagacaa tcaaatatta
    15901 cagaacgatt aatccacgta tttcatcgcg acccttgaag tcaggcgcgt aataagttcg
    15961 taagcgctta ctttcgtcat ttcagcgata cgttctacgg gcaaaccttc gccccataaa
    16021 atgaccggat ccccggcttt gtcctgcgcc tgtggaccta agtctacgca gatcatatcc
    16081 atcgccacgc gcccgacaat cggtacttcg cgaccgttca ccagcactgg cgtaccggac
    16141 ggcgcggcgc gcggataacc atcgccatag cccatcgcga ctacgccaag acgggtatca
    16201 cgttcgctta cccaggttcc accataacca acaggctctc cggctttatg ctcacgcacg
    16261 gcaatcaggc tggaggttag tgacatcact ggctgacagc caaaatcggc accggtggag
    16321 cgatcttcca gcggcgagac gccataaaga atgatgcccg ggcgcaccca gtcaaaatgc
    16381 gactgtggcc acagcagaat gccacccgac gcggcaatgg aacgttgacc aggtttgcct
    16441 tcgcaaaagg tattaaagat agcgagttgt ttctcggttg cgccacattt tggttcatcc
    16501 gcgcgcgcaa aatggctgac gatattcacc ggctgacgaa cgtttttgca ctgggtcagg
    16561 cgatgataaa acgcctcagc ctgttccggc cttacgccca gacggtgcat accggtatcg
    16621 agtttcatcc agacggtaac cggctcgtcc aggctagcct cttccagcgc agccagctgt
    16681 tcttcgttat gcacggcggt atgaaaatgt tgcgcagaaa tcgtcggcag atctctggca
    16741 tcaaaaaagc cttcgagtaa cagtacaggt ttggtgattc cccccgcacg cagtcgcaga
    16801 gcttcttcga gacgggctac gccaaaggcg tcagcatcgg ggagcgttcg cgcggtctca
    16861 agaagaccgt gaccataagc gttcgctttc accaccgcaa ccattttact ggcaggggcc
    16921 agttcacgaa gacgttgcag gttgtgtcgc agagcgcggc ggttaatcac aacagttgcc
    16981 gcttgcattt gtgttccttg ataagtgttt gctttaatta cctaattcat aaaataatta
    17041 ttattcgtcg tcgtactgcg gccccgcata gttgtcgaag cgcgaccatt gaccgttaaa
    17101 ggtcaggcgt accgtcccga ttgggccgtt acgttgttta ccgataataa tttccgcgat
    17161 gccttttaaa tcactgtttt cgtgatacac ctcatcacga tagataaaca tgatcaagtc
    17221 cgcatcctgc tcgatagagc cagattcacg caggtcggag ttgaccgggc gtttgtcggc
    17281 acgttgttcc agagaacggt tcaactggga cagcgccacc accggcacgt tcagttcttt
    17341 cgccagtgct ttcagcgagc gagagatttc tgcaatttcc agcgtacggt tatcggaaag
    17401 cgccggtacg cgcatcagtt gcaggtagtc gatcatgata agcccgatgc cgccgtgttc
    17461 acgggcaata cggcgtgcgc gggaacgcac ttccgttggc gtcaggccgg aggagtcatc
    17521 gatatagata ttgcgttttt cgagcaaaat acccatggtg ccggaaatgc gcgcccagtc
    17581 ttcgtcatcg agctgcccgg tacggatttt agtctggtca acgcgcgaca gcgacgccag
    17641 agaacgcatc atgatctgtt ctgatggcat ctccagcgag aagataagta ccggtttatc
    17701 ctgcaacatc gccgcgtttt cgacgaggtt catcgcaaat gttgttttac ccatcgacgg
    17761 acgcgcggcg acgatgatca aatccgacgg ctgcaagcca gcggtttttt tgttgagatc
    17821 gtcataaccg gtgtttaccc cggtaacgcc atcgtgtggc tgctgaaaca actgctcaat
    17881 acgcgccacg gttgcgtcga gcacatcggc gatgttcttc ggcccttcgt ctttgttcgc
    17941 acgactttcg gcaattttaa agacgcggga ttcagccaga tccagcagat cttcgctggt
    18001 acgcccctgc ggatcaaaac cagcttcggc aatctcattc gcaaccgaga tcatctcacg
    18061 gacaacggca cgttcacgca cgatgtccgc ataggcactg atgttagccg cacttggcgt
    18121 attttttgac agctctgcca gataagcaaa accaccgacg ctatcgagtt gcccctggcg
    18181 ttccagcgat tccgcaagag taatcagatc gatagggcta ccgctttcct gcaaacgcgc
    18241 catttcagta aagatatgac ggtgtgggcg ggtgtaaaaa tcgtctgcta ccacacgctc
    18301 ggctacatca tcccagcgtt cgttatctag cattaaaccg cccaacaccg actgctccgc
    18361 ttcgatcgag tgcggaggca ctttcagccc ggcaacttgt ggatcgcgtt cgcggggttc
    18421 agcctgctgt ttgttgaagg gtttatttcc tgccatagtg aatggagtta ccgagataaa
    18481 gaatgggtcg aaactttatc atatgaagca gaccctgacg atacgttctg gaggacacat
    18541 ggcaacacga attgaatttc acaagcacgg tggcccggaa gtacttcaag ccgtagagtt
    18601 cactcctgcc gatccggcgg agaatgaaat ccaggtcgaa aataaagcca tcggcatcaa
    18661 ttttatcgac acatatatcc gcagcggcct ttacccgccg ccatcgctac ccagcggatt
    18721 aggcaccgaa gcagcaggca tcgtgagtaa agtcggcagt ggtgtaaagc atattaaggc
    18781 aggcgatcgt gtagtctatg cgcagtcggc gttaggcgct tacagctctg tgcataacat
    18841 tattgcggat aaagcggcga ttctgcctgc ggcaatttct tttgagcaag ctgcggcatc
    18901 cttcctgaaa ggcttaacgg tttattatct gctgcgcaaa acctatgaaa ttaaacccga
    18961 tgaacagttc ctgttccacg cagcggctgg cggcgttggc ttaattgcct gccagtgggc
    19021 aaaagccctg ggcgcgaaac ttatcggcac cgtaggaacc gcgcaaaaag cgcagagcgc
    19081 gctaaaagcg ggcgcgtggc aggttattaa ctatcgtgaa gaggatctgg tcgagcggtt
    19141 aaaagagatc accggcggta agaaagtgcg cgtggtgtac gattccgtgg gcagagacac
    19201 ctgggaacgg tcgctggatt gcctgcaacg ccgcggctta atggtcagtt ttggcaactc
    19261 atcaggtgcg gttaccggtg tgaacttagg cattctcaat caaaaaggct cgttgtatgt
    19321 gacacgccct tccctgcaag gctatatcac cacgcgggag gaattaaccg aggccagtaa
    19381 tgaactgttc tctttgattg ccagcggtgt gattaaggtc gatgtcgccg agcagcagaa
    19441 atatccgctg aaggatgcgc agcgtgcgca tgagattctg gaaagccggg cgacgcaagg
    19501 ttccagcctg ctgattccat aaaagaaata gggcttccac ctgggaagcc ctttcttttt
    19561 atagttcggc tgtatgtagg gtacagcacg atgaatctgt tagaggcgca atagtgacag
    19621 atttgattat caattcctat tttgttctaa ggataaaacc ttaggttgtg atcatccgca
    19681 caatccctta gtaacgccag cggtcataac gctgatattt cggcactttt ggtgctttaa
    19741 tcgccttaat aacccacacc accgcaatcg ccagtagtaa ccacggcagc aacttaatca
    19801 tcaatgccag cataccgccg aggaacataa tggccgtcgc cacaaccagc gcggcgataa
    19861 tgcccagcaa cgaaacgccg gtgaccatca gcatgacaaa aaagccaatc acaaaaagta
    19921 gttccagcat gatgctctcc caaatatgaa atctcttgct ggcattacaa gaatcatgcc
    19981 aaaaataatc tattgattta acagcaaaac gccccgcgac ggtgcgcagg gcgtggtgaa
    20041 tttgactact ttttggtgaa aagttaacgc ttatccgcca ccagtttgag cgcgtgttcc
    20101 agcacattaa tgtctgcacc cgctttatgg gcattttcac ttaaataacg ccgccactgc
    20161 cgcgcgccag gaataccctg gaacaagccc aacatatgcc gggtaatatg gccgagatac
    20221 gtcccctggc tgagttcacg ctcaatgtac ggatacatgg cgcgcactac cgccaccgga
    20281 tcggcatcgg tatccgagga accaaagatc tcccggtcta ccgccgccag aatacccgga
    20341 ttctgatacg cctcgcgccc gaccatcacg ccatccatat gttgcaggtg tgctttggcc
    20401 tcttccagcg acttgatacc accgttaatc gacattgtca gatgcggaaa gtcacgcttc
    20461 agttgataca cacgcggata atcgagcggc gggatttcac ggttttcttt cgggcttaac
    20521 cccgaaagcc aggctttacg tgcgtggatg atgaacatct cacactcgcc tttgccggaa
    20581 acggtattga tgaaatcgca gagaaattca tagctgtcct ggtcgtcgat gccaatacgc
    20641 gttttcaccg tcaccggaat cgacaccaca tcgcgcatcg ctttcacgca gtcggcaacc
    20701 agctgcgcat tacccatcag acacgcacca aacatgccgt tctgcacccg gtcagacggg
    20761 cagccgacat tcaggttgat ctcatcatat ccgcgcgctt ctgccagctt tgcacactgc
    20821 gccagcgccg ccggatcgct accgcccagt tgcaacgcta ccggatgttc ttcttcactg
    20881 tacgccagat aatcaccttt accgtgaata atcgcccctg tggtcaccat ttcggtatac
    20941 agcaacgtat tgcgggaaag cagacgcaag aaatagcggc aatgtctgtc cgtccagtcg
    21001 agcattggtg caacgctaaa ccgaccactc cagtgaacgt cagttttttc aggcattgcg
    21061 ctggtttggt tgattttttg catttcagaa ttaccgtgca ttttcaaatg tagagattat
    21121 tttatcgata tatcatgggg ttatgttatt cagcatcact attcaggagg ctcaatagcg
    21181 gggtactata ccataacaac aggaagcgcc tgtctcattg caaaagaaaa ttgagatcct
    21241 ctcaaggcat gaagctctca cgaagtgatg gaaataatct tattagccgt taactttgtt
    21301 aaggccaatg ataaacaatc caggttcgac gataaataaa aaatcacaca ttaaactctg
    21361 gtgatatatc tccctgctaa tagcattgat agagaaaaaa gaacccaata aatattgggt
    21421 ccttttatat aatgccttcc atactatcga agaacttcac atattatttc tccgatttaa
    21481 ccccgaacaa atcataaatt aatttagaag tgtctgtaag tattttaatc tcttcctttg
    21541 aggttgggtc aaacgacttc gcgaagctaa ttaattgtgg tgcagcatct cgcattttgc
    21601 ttaaaatatc aggatcgagc gttccttcat tcaccagatg tgacatctta tccagatagc
    21661 catcaaaatt catttctccc ccatcagcca gacgcttcat ctctcccagg tacttcttca
    21721 tatcacgttg agataatttt tcaaactgag ctttcaggta gctctcatta ttttcattaa
    21781 tatacactgt ttctgataaa tctgcgtagg cactagaata tgaaagtgaa attaacagcg
    21841 aagcaaataa ttttaagctg ttgtcatcat gttcctggca ggcattaaca aacgttaaaa
    21901 aaccagaacc tattgcttga aaatgtatat tcgctaaagg ttcattatcc ttagattcct
    21961 cataaaatag ctgaaccgtg gagggaaggt cattcttagt ttctacatca aaagtacatt
    22021 gttcaatggg cattgcatct ttattatccc caggattaca tatactatta atcgcgaaat
    22081 gaaaaatagc ccggtcaaca actgatgcaa taaagtcacg atcgtttaaa tcctcatcag
    22141 tgcaatcgtc aatatactta ttgacccaca ttttgagatc atttatttgc acaattaaaa
    22201 acacattttt ttacgtgcat gccataaatt atgcgtgatt cgttgaataa acaaatctat
    22261 ttttgcaata attatatccc gatgacgcag cgctgcataa tcaatagatt taccatatat
    22321 attatttaat ttacctttga ttgaacctct attatctaat ttatctttga ttgcatcttc
    22381 attatcgaat tgatttgaat tgagtgtttt attaaagtat ccagttgcac cgggtattat
    22441 cttcaacatg attcatctac cttttttgtc gtaccgtgtc ctccttataa ttcttttgcc
    22501 atctggtcac tatcaaaaat cgctcataat ttctgaacta caggtatgcg tttaaaccca
    22561 gttaaataaa tagcgagtta acttgaagca atttatttaa aaatgaatta ttaattatta
    22621 tcgtgttgat aatggtacga caaggcaaca taacacctta cctacaaaac agaaaatcaa
    22681 cattacggca acaataaggg ttctcggtgt ttttcctgga acatggtaaa gtaaggacat
    22741 tcttaacccc cactttgagg tgcccgatgg aaaagaccac aacgcaggag ttattagcgc
    22801 aggctgaaaa aatctgcgcg cagcgtaatg tgcgcctgac cccacagcgc ctggaagtgt
    22861 tgcgcctgat gagtctgcag gatggcgcta tcagcgctta tgatctgctt gatttactgc
    22921 gcgaagctga accgcaagcc aagccgccaa cggtttatcg cgcgctggat tttctgcttg
    22981 agcaaggttt tgtgcataag gtggaatcca ccaacagtta tgtgctctgt catctgttcg
    23041 atcagcccac ccatacgtca gccatgttta tttgcgatcg ctgcggcgca gtgaaagaag
    23101 agtgtgcaga aggcgtggaa gacattatgc atacgctggc ggcaaaaatg gggtttgccc
    23161 tgcggcataa tgtgattgaa gcacatgggc tctgtgcggc atgtgtagaa gtggaagcgt
    23221 gtcgtcatcc tgaacagtgc cagcatgatc actctgtgca ggtgaaaaag aaaccgcgtt
    23281 aagagggcgt acatccttgt acacgtcggg caggagggat taattaccag cgatattcat
    23341 tgcgggtttc ccaatccacg acctcttttt ctgcctgatc tttctgataa ccataacgtt
    23401 cctggatttt accgaccagt tgatcacgtt taccttcaat gatcgtcata tcatcatcgg
    23461 tcagtttgcc ccattgctct ttcactttac ctttaaactg tttccagtta ccgccggctt
    23521 catctttatt cataatcaag acctcatcgt taggttgtga atgagagtac gttcactttt
    23581 cttctgaacg tgagattaag tgtagtcagc aatttggctt aggattattt attcagaatt
    23641 tttaaccgtc acgttgcggc aaaccaggta ccattgcgcc agtgacgccg ccagatagcc
    23701 gccagagaaa gcccgcgcaa cgccagaaag acggttaatg ccagccacaa agcatgatta
    23761 cccagccacg gcagcgtaag gagcgtcagc gcaaaacctg cggcggccac cgccatactg
    23821 ttacgcattt cggtggcacg cgttgcgcct ataaacatgc cgtccagcag ataacaccag
    23881 acgccaacca ccggcaaaat cacctgccag ataagatagc ggtcagccag ctgctgaatc
    23941 tgggttaacg acgtcagtaa cgcaatgatg tgttccccag ccagcaaata aaccaccgaa
    24001 aacagtaacg ctacgatccc cgactggcgg cacgctgccc gccagacatc cagcaactgg
    24061 ctaccgtcgc gcgcaccgta tgcctgaccg gagtgcgctt caaccgcgta ggcaaaacca
    24121 tccagcgcat aggcggtaaa ggtgagtagc gtcatcagaa ccgcgttaac agcgataatg
    24181 tcactcccca gtcgcgcgcc aagtacggtg atcgcgccga aacagagttg caacaacagc
    24241 gaacgcagca tgatatcgcg gttaagcgcc agcaagcgac ggaagtttcc tcgccaggca
    24301 gttttcagca tttcgccgga aattccgcgt agtttgagga ttttacgcac cattagcaga
    24361 ccaatcagca atgttgcata ttccgcaata accgtcgcca gcgccgcgcc ctgcacgttc
    24421 atatgcagcc ccatcaccag ccagacatcc agcacaatgt tgaggatatt gccgaccact
    24481 aacaaaatta ctggcgcacg ggcatattgc acgccgagta accaaccgag taataccaga
    24541 ttcgccagcg acgccggtgc gcttaaccag cggatttcaa gaaagcgccg cgcctgttcc
    24601 aggactgcct cactaccgcc aacaatatgc agcgccagat cgataatcgg cgtacgcagc
    24661 agcgcaatta acgccccagc ccccaacgcc aacagcaacg gttgcaccag cgtacgggct
    24721 aatgcctgag gatttttggc accataagcc tgcgcagtca gcccggtggt gctcatgcgt
    24781 aaaaacagca acagcataaa gagaaagctg gtcgccgttg caccaaccgc cacgccgccc
    24841 aaataaaccg ggctatcaag atgaccaatt accgccgtat cgaccagtcc cagcaacgga
    24901 acggtgatat tggagaaaat catgggtaag gcgagatgcc agagtgcttt atcagatgaa
    24961 gtgaggaatg ccatgcagac aagcctgatg aagagagatg aaaaacaaac cgcgacgcca
    25021 ggcggcatcg cggtctcaga gatatgttac agccagtcgc cgttgcgaat aaccccaacc
    25081 gccagccctt caatggtgaa gctctgctga cgaaggtcaa cgacaattgg tttaaactcg
    25141 ctattttctg gcaacagttc gactttattg ccctgttttt tcaggcgctt aacggtaact
    25201 tcgtcatcaa tacgtgcgac aacgacctga ccgttacgta catcctgagt tttatgcact
    25261 gccagcaagt caccatccat aatgccgata tctttcatcg acatcccgct gacgcgcagc
    25321 aggaaatcag cattcggctt gaataaggaa ggatcgacct gataatgacc ttcaatatgc
    25381 tgttgcgcca gaagtggttc accggcagcc acacgaccta ccagcggcaa cccttcttcc
    25441 tcttcctgca acagacgaat cccgcgtgat gcgccggaaa caatttcaat aacgcctttg
    25501 cgtgccagcg ccttcagatg ttcttcagcc gcgtttgggg aacggaaccc caaacgctgc
    25561 gcgatttccg cacgcgtcgg cggcatacct gtctggctga tgtgatcacg gatgagatca
    25621 aacacctctt gttgcctggc cgttaacgct ttcattccgc cccctgggtg tatatacagt
    25681 tatgctgtga gtatatacag caaaaggcga ttttggaacc ataaactgca caataaacca
    25741 gagatttatc gaattctgga agggttatcc aaaatgcgac cataacagaa tgcaccaggt
    25801 aatcacggcg acgataatgg caatcagcac cgcagcggat cccatatctt ttgcgcgtcc
    25861 ggaaagctca tggtattcag agccaattcg gtcaaccact gcttcgatgg cgctattgag
    25921 gatttccaca atcatcacca gcatcacgga gctgataagc agcacgcggg taatcgcgtc
    25981 cacatccagc cagcaggcga tgaccaccgc caacaatacc gctacgcctt cctgacggaa
    26041 tgccgcttcg ttgatccatg cagcgcgtaa acctttccag gaatagccag cagctttgat
    26101 aattcgggtg aatccagtgg tattattggc cattgaaaga acctttttac attatgagcg
    26161 tcaatatcag tgtaccgtta aatccgatga ttcgggtttg cgtagcgccg cgcgaaacat
    26221 gagcggatac cacagaattt cccatgactt tctgctatcc ttgccgcgca tttgcattat
    26281 taaccagagg ctttacatcg tttatgtccg gctggccacg aatttactac aaattactga
    26341 atttaccatt aagcatcctg gtaaaaagca agtctattcc ggcagatcct gccccggaac
    26401 tggggctgga tacctctcgt ccaattatgt acgttttacc gtacaactcg aaagcagatt
    26461 tgctgacgtt gcgcgcccag tgtctggcac atgacttgcc tgacccgtta gagccgctgg
    26521 aaatcgacgg cacgctactg ccgcgctatg tgttcattca cggcgggccg cgtgtgttca
    26581 cctattacac gccgaaagaa gagtctatta agctgttcca cgactatctc gatttgcacc
    26641 gtagcaaccc aaatctggat gtgcagatgg tgccagtgtc ggtgatgttt ggtcgcgcgc
    26701 cggggcgtga aaaaggcgaa gtgaacccgc cgctgcgtat gcttaacggc gtacagaaat
    26761 ttttcgctgt actgtggctc ggtcgcgaca gttttgtgcg tttctcgccg tcagtttcgc
    26821 tgcgccgtat ggcggatgaa cacggcacgg ataaaactat cgctcagaaa ctggcgcgcg
    26881 tggcgcgtat gcactttgcc cgtcaacgtc tggctgccgt aggcccacgt ttgcctgctc
    26941 gtcaggatct gtttaataag ctgctcgcct cccgcgccat tgccaaagcg gtagaagatg
    27001 aagcgcgcag caaaaaaatc tcccatgaaa aagcgcagca gaacgcgatt gcactgatgg
    27061 aagagattgc ggcgaatttc tcttacgaga tgattcgcct gactgaccgt attctgggct
    27121 tcacctggaa ccgactttac cagggcatca acgtccataa cgctgagcgc gttcgccagc
    27181 tggcccacga cggtcatgag ctggtatatg tgccttgcca ccgcagtcac atggactacc
    27241 tgctgctttc ttacgtgctg tatcaccagg ggctggtgcc gccgcatatc gccgccggga
    27301 tcaacctgaa tttctggcct gccgggccga ttttccgccg tctgggggcg ttctttattc
    27361 gccgtacgtt taaaggcaat aaactttatt ccaccgtttt ccgggagtat ctcggcgaac
    27421 tgttcagccg tggttattcc gtcgagtact tcgtggaagg cggtcgttcc cgtacggggc
    27481 gtttgctgga tccgaaaact ggtacgctgt cgatgaccat tcaggcgatg ctgcgtggcg
    27541 gcacgcgtcc gattacgctg attccgatct atatcggtta tgagcacgtc atggaagtgg
    27601 gtacttacgc caaagaactg cgcggcgcga cgaaagagaa agagagcctg ccgcagatgc
    27661 tgcgcggttt aagcaagctg cgtaatctcg gtcagggtta cgtcaacttc ggtgaaccaa
    27721 tgccgttgat gacctacctt aaccagcatg tacctgactg gcgtgaatct atcgatccca
    27781 tcgaagcggt gcgtccggca tggttaacgc cgacggtcaa taatattgct gccgatctga
    27841 tggtacgcat taacaacgca ggcgcggcaa acgccatgaa cctgtgctgt actgcgctac
    27901 tggcatcacg tcagcgctca ctcacccgcg agcagttaac cgagcaactc aactgctacc
    27961 tggatctgat gcgcaacgtg ccctactcca cggactctac cgttccttca gccagcgcca
    28021 gcgagcttat cgatcacgcg ctgcaaatga acaagtttga agtcgagaaa gacacaatcg
    28081 gcgacatcat cattctgccg cgcgagcaag cggtgctgat gacctactat cgcaacaaca
    28141 ttgcgcatat gttggtgctg ccttcgctga tggcggcaat cgtcacccag catcgccaca
    28201 tctcccgcga cgtattgatg gagcacgtca atgtgcttta cccaatgctg aaagcggagc
    28261 tgttcctgcg ctgggatcgc gacgagttgc cggacgttat tgatgcgctg gcaaatgaga
    28321 tgcaacgtca ggggctgatt accctgcaag atgatgagtt gcatatcaac ccggcgcatt
    28381 ctcgcacgct acagctgctg gccgcaggcg cgcgcgaaac gctgcaacgt tatgccatca
    28441 ccttctggtt gttgagtgcc aacccgtcga tcaaccgcgg tacgctggag aaagagagcc
    28501 gcaccgtcgc gcaacgtctc tccgtgctgc acggcatcaa cgcgccggag ttcttcgaca
    28561 aggcggtgtt cagttctctg gtgctgacac tgcgtgatga agggtatatc agcgatagcg
    28621 gcgatgccga accggcagaa acgatgaagg tttatcagtt gctggcggag ttgattacat
    28681 cagacgtgcg tttgacgatt gagagtgcga cgcagggcga agggtaatca gagagaattg
    28741 ccggatgcgg cgaaaacgcc ttatccggcc ttccataatc tgcaaattca ataaattgcg
    28801 atgtgttgtg taggcctgag aagcgccgcg catcaggcaa cccagaagaa agccggatga
    28861 tcatccggct tttttacatc atcagaaatg ccagtaactc attgccagcc ctaaaaatag
    28921 taccagacca acatagttat tattcataaa tgctttaaag caggcttcac gctcgcggtt
    28981 ggcaatcagt ttttgttgat aaacaaacag cgcgccagcc accagaattg accagtaata
    29041 tccccagcct aagccattta actcaccgat gatcgccatc agtgccagta cgccaatctg
    29101 caaaatacca ataatcaatt tatcgtattg gccgaacagg attgccgtgg atttaatgcc
    29161 aatcttcaca tcatcatcgc ggtcaaccat cgcatactgc gtgtcgtaag ccaccgccca
    29221 gagaatattg gcgaggaaca ttaaccagca actcaatggc accgactcac tcacagcggc
    29281 aaaagccatt ggaatcgacc agccaaacgc cgcgcccagc accacttgcg gtagatgggt
    29341 ataccgcttc ataaacgggt acacccacgc cagcgctagc gcggcaatcg acaacagaat
    29401 ggtcatcgta ttcagcgtca gcaccagtaa aaacgaaatc agtaccagca cgacaaacag
    29461 cgcgcgcgcc tctttctctg ttaccgcgcc gctgggaagt ggtcggttcg ccgtgcgctt
    29521 aacatgacca tcaaacttgc ggtcagcata atcattcacc acacatccgg cagcgcgcat
    29581 cagccagaca cccgcgacaa acaccgccag gatccagagc tggggaacgc ccggtgtcgc
    29641 cacccacaac gcccataatg ttggccagag cagcagtaac gcgccaattg gcttatccgt
    29701 acgcattaag cgatgaaacg ccagcagctt attctgcgtc agactccact ccatattttt
    29761 ttcctcttag tacaacggtg acgccggtaa aaacagttct gttagcaaca gcggtttacc
    29821 gcttaatcgc aggcgggaac gtcgccccca cagcccggca tcacggccta tctcaataaa
    29881 gtcccgggtt aatgtcgatg atgtgaacag atagcgtcct aacggcgttt tacccaattt
    29941 ttgtaacgcc agctccggcc cgcttaacgt tgacacagga acgacggtac gaccggcaag
    30001 ccacggttca ccatcggcac ataacaaaat ttcacgtaac cagtaacgag actctttcgg
    30061 cagcagcggc agttcttcgg ggatttcatt ctgctcgaca aacccttcgc ggatcatcgt
    30121 cacgcttacc gtttttccct gctgttcaaa acgttttgtc atggaatcct ccagcaacag
    30181 ccagtcgagc agttgcggat ccagggcagg gatctcttta caatagcgca gcgcacgcag
    30241 ttgcgttaac gcggggtgtg acatgccgaa ctctccgtta cataacgtaa aggcattgta
    30301 tcgcagaaaa gtgtttacgg gagatgtaaa gcaaattaag tgatctaata cgcaacaaaa
    30361 acgcaacaat cgcatgaagt ggtaaaacga tgttgaacct tacgctttac cgatgcccgt
    30421 gctggcgagg gcaaccgtag gggcatcacc gtccaggatg ccaggaacgg tgatgttttc
    30481 ctttacttaa acacccttat tcattatacg atgagctcgc caactcgcag taaaaatggg
    30541 gaaaagcgca tatttaccat gagatttgga gctgaaaagt gtttcctgag taagattaac
    30601 aggcaacatc tcatgtctgg atttgtagat atacgtggaa ttccaattgg tatcttttgt
    30661 aggattcaac atatcatgta agcgctggga gcttaccacc ataactggcc catcatcgac
    30721 tgaggagaac aggataaaga tattatcgtt tcgtgttaat tcattcgtgt taaaggttct
    30781 taaattatct tcagtttcta taaatatagg tgaaacatca tcactacgaa tccactcttt
    30841 ataaagatgc caaacatttg ctttgatcat atcatccgtt gatcgtaagg cctgatcgat
    30901 aagttggata aaaaaattgt tatttttatc aattagccat ttattcgtat taaatctgtt
    30961 aataaaatcg atcatctgtt gggtatcgaa attcacctca ctgaatcgat gttgacgcat
    31021 aaaatcatcg aacttgttat
//
LOCUS       DACAOP010000052        29999 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.052, whole genome shotgun sequence.
ACCESSION   DACAOP010000052 DACAOP010000000
VERSION     DACAOP010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29999
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.052"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            47..586
                     /locus_tag="IT892_002599"
     CDS             47..586
                     /locus_tag="IT892_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415458.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial subunit ElfA"
                     /protein_id="HAP3135802.1"
                     /translation="MKKSVLTAFITVVCATSSVMAADDNAITDGSVTFNGKVIAPACT
                     LVAATKDSVVTLPDVSATKLQTNGQVSGVQIDVPIELKDCDTTVTKNATFTFNGTADT
                     TQITAFANQASSDAATNVALQMYMNDGTTAITPDTETGNILLQDGDQTLTFKVDYIAT
                     GKATSGNVNAVTNFHINYY"
     gene            669..1370
                     /locus_tag="IT892_002600"
     CDS             669..1370
                     /locus_tag="IT892_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HAP3135803.1"
                     /translation="MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEG
                     EEQISMGVRNTSPDVPYLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGA
                     PLAKDRETLFFTSVRAVPSTTKRKEGNTLKIATQSVIKLFWRPKGLAYPLGEAPAKLR
                     CTSSADMVTVSNPTPYFITLTDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRT
                     INDYGAETPQLNCKS"
     gene            1395..3995
                     /locus_tag="IT892_002601"
     CDS             1395..3995
                     /locus_tag="IT892_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HAP3135804.1"
                     /translation="MYRTHRQHSLLSSGGVPSFIGGLVVFVSAAFNAQAETWFDPAFF
                     KDDPSMVADLSRFEKGQKITPGVYRVDIVLNQTIVDTRNVNFVEITPEKGIAACLTTE
                     SLDAMGVNTDAFPAFKQLDKQACVPLAEIIPDASVTFNVNKLRLEISVPQIAIKSNAR
                     GYVPPERWDEGINALLLGYSFSGANSIHSSADSDSGDSYFLNLNSGVNLGPWRLRNNS
                     TWSRSSGQTAEWKNLSSYLQRAVIPLKGELTVGDDYTAGDFFDSVSFRGVQLASDDNM
                     LPDSLKGFAPVVRGIAKSNAQITIKQNGYTIYQTYVSPGAFEISDLYSTSSSGDLLVE
                     IKEADGSVNSYSVPFSSVPLLQRQGRIKYAVTLAKYRTNSNEQQESKFAQATLQWGGP
                     WGTTWYGGGQYAEYYRAAMFGLGFNLGDFGAISFDATQAKSTLADQSEHKGQSYRFLY
                     AKTLNHLGTNFQLMGYRYSTSGFYTLSDTMYKHMDGYEFNDGDDEDTPMWSRYYNLFY
                     TKRGKLQVNISQQLGEYGSFYLSGSQQTYWHTDQQDRLLQFGYNTQIKDLSLGISWNY
                     SKSRGQPDADQVFALNFSLPLNLLLPRSNDSYTRKKNYAWMTSNTSIDNEGHTTQNLG
                     LTETLLDDGNLSYSVQQGYNSEGKTANGSASMDYKGAFADARVGYNYSDNGSQQQLNY
                     ALSGSLVAHSQGITLGQSLGETNVLIAAPGAENTRVANSTGLKTDWRGYTVVPYATSY
                     RENRIALDAASLKRNVDLENAVVNVVPTKGALVLAEFNAHAGARVLMKTSKQGIPLRF
                     GAIATLDGVQANSGIIDDDGSLYMAGLPAKGTISVRWGEAPDQICHINYELTEQQINS
                     AITRMDAICR"
     gene            3986..5056
                     /locus_tag="IT892_002602"
     CDS             3986..5056
                     /locus_tag="IT892_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3135805.1"
                     /translation="MQIIFGEKCVSLLRLFFAAVLMLWCAQTAAYSGQCHTTQGNPYI
                     GVNFGVKTLEEEANTAGVVKDKFYQWNESNDYYVSCDCDKDNVRSGRWAFAADSPLVY
                     LGDNWYKINDYLAAKVLLQVKGSSPTAVPFENVGTGGDTRWHICDPGGQRLGGQGASG
                     NSGSFSLKILQPFVGSVVIPPMALARLYECYNIPAGDSCTTTGTPVLVYYLSGTINSL
                     GSCSVNAGETIEVDLGDVFAANFRVVGHKPLGARTAELAIPVRCNTGNAGLVNVNLSL
                     TATTDPSYPQAIKTSRPGVGVVVTDSQNNIISPAGGTLPLSIPDDADSIARMNVYPVS
                     TTGVPPETGRFEATATVRINFD"
     gene            5068..5610
                     /locus_tag="IT892_002603"
     CDS             5068..5610
                     /locus_tag="IT892_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3135806.1"
                     /translation="MKKKTIFQCVILFFSILNIHVGMAGPEQVSMHIYGNVVDQGCDV
                     ATKSALQNIHIGDFNISDFQAANTVSTAADLNIDITGCAAGITGADVLFSGEADTLAP
                     TLLKLTDTGGSGGMATGIAVQILDAQSQQEIPLNQVQPLTPLKAGDNTLKYQLRYKST
                     KAGATGGNATAVLYFDLVYQ"
     gene            5618..6133
                     /locus_tag="IT892_002604"
     CDS             5618..6133
                     /locus_tag="IT892_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415463.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HAP3135807.1"
                     /translation="MLKRIIWILFLLGLTWGCELFAHDGTVNISGSFRRNTCVLAQDS
                     KQINVQLGDVSLTRFSHGNYGPEKSFIINLQDCGTDVSTVDVTFSGTPDGVQSEMLSI
                     ESGTDAASGLAIAILDDAKILIPLNQASKDYSLHSGKVPLTFYAQLRPVNSDVQSGKV
                     NASATFVLHYD"
     gene            6099..6836
                     /locus_tag="IT892_002605"
     CDS             6099..6836
                     /locus_tag="IT892_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HAP3135808.1"
                     /translation="MPARHLYFIMTNTWNRLALLIFAVLSLLVAGELQAGVVVGGTRF
                     IFPADRESISILLTNTSQESWLINSKINRPTRWAGGEASTVPAPLLAAPPLILLKPGT
                     TGTLRLLRTESDILPVDRETLFELSIASVPSGKVENQSVKVAMRSVFKLFWRPEGLPG
                     DPLEAYQQLRWTRNSQGVQLTNPTPYYINLIQVSVNGKALSNVGVVPPKSQRQTSWCQ
                     AIAPCHVAWRAINDYGGLSAKKEQNLP"
     gene            6947..7957
                     /gene="pyrD"
                     /locus_tag="IT892_002606"
     CDS             6947..7957
                     /gene="pyrD"
                     /locus_tag="IT892_002606"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HAP3135809.1"
                     /translation="MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPA
                     KPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFR
                     LVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICME
                     KIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKI
                     APDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKST
                     EIIRRLSLELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVT
                     HI"
     gene            8131..8673
                     /gene="zapC"
                     /locus_tag="IT892_002607"
     CDS             8131..8673
                     /gene="zapC"
                     /locus_tag="IT892_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415466.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapC"
                     /protein_id="HAP3135810.1"
                     /translation="MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFARKMLTPDAF
                     SPAGFCVDDAALYFSFEEKCRDFNLSKEQKAELVLNALVAIRYLKPQMPKSWHFVSHG
                     EMWVPMPGDAACVWLSDTHEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKI
                     MNDRLKPQVNVDSFSLEQAV"
     gene            complement(8670..9779)
                     /gene="ycbX"
                     /locus_tag="IT892_002608"
     CDS             complement(8670..9779)
                     /gene="ycbX"
                     /locus_tag="IT892_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein YcbX"
                     /protein_id="HAP3135811.1"
                     /translation="MATLIRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGT
                     FITARQFPQMVRFTPSPVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIA
                     PDAINKWLSEFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRYLQQ
                     RCPASVKMEQFRPNLVVSGASAWEEDRWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQ
                     KHPAGEPLKTLQSFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAA
                     ADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQ
                     LLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLAR"
     gene            10023..12131
                     /gene="rlmKL"
                     /locus_tag="IT892_002609"
     CDS             10023..12131
                     /gene="rlmKL"
                     /locus_tag="IT892_002609"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /protein_id="HAP3135812.1"
                     /translation="MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLV
                     YQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAINWTEMFNPGATFAVHFSGLNDTI
                     RNSQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIRVNVWLHKETASIALDLSGDGLH
                     LRGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGL
                     HRGRWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNAR
                     LAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYGERLDSEPALIALHSLLGRIMK
                     NQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESTPDSKPAMVA
                     EDYTNRLRKNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYADWVVVQEYAPPKTI
                     DAHKARQRLFDIIAATISVLGIAPNKLVLKTRERQKGKNQYQKLGEKGEFLEVTEYNA
                     HLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSATVHAGLGGARSTTT
                     VDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLAWLREANEQFDLIFIDPPTFSNSKR
                     MEDAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKRGFRMDLDGLAKLGLKAQEITQKT
                     LSQDFARNRQIHNCWLITAA"
     gene            12143..14050
                     /locus_tag="IT892_002610"
     CDS             12143..14050
                     /locus_tag="IT892_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP3135813.1"
                     /translation="MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKST
                     LMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNVEGSVYDFVAEGIEEQAEYLKRYH
                     DISRLVMNDPSEKNLNELAKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGG
                     WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRN
                     MATRIVDLDRGKLVTYPGNYDQYLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKA
                     RRTRNEGRVRALKAMRRERGERREVMGTAKMQVEEASRSGKIVFEMEDVCYQVNGKQL
                     VKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRA
                     ELDPDKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLL
                     LARLFLKPSNLLILDEPTNDLDVETLELLEELIDSYQGTVLLVSHDRQFVDNTVTECW
                     IFEGGGKIGRYVGGYHDARGQQEQYVALKQPAVKKTEEAAAAKAETVKRSSSKLSYKL
                     QRELEQLPQLLEDLEAKLEALQTQVADASFFSQPHEQTQKVLADMAAAEQELEQAFER
                     WEYLEALKNGG"
     gene            14180..15433
                     /gene="pqiA"
                     /locus_tag="IT892_002611"
     CDS             14180..15433
                     /gene="pqiA"
                     /locus_tag="IT892_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiA"
                     /protein_id="HAP3135814.1"
                     /translation="MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAW
                     DAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTF
                     FLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
                     KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIR
                     QGLRSCSCCTAILPADEPVCPRCSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIM
                     VTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHG
                     KRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIM
                     TMFSAMTFDPRLSWDRQPESEHEES"
     gene            15438..17078
                     /gene="pqiB"
                     /locus_tag="IT892_002612"
     CDS             15438..17078
                     /gene="pqiB"
                     /locus_tag="IT892_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HAP3135815.1"
                     /translation="MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPE
                     VTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDT
                     VFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRV
                     ILDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTNNVRF
                     WKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGQPVAPKTAFVLYDDQKS
                     IQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYR
                     IPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNT
                     PAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRT
                     MKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRL
                     DQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ"
     gene            17075..17638
                     /gene="pqiC"
                     /locus_tag="IT892_002613"
     CDS             17075..17638
                     /gene="pqiC"
                     /locus_tag="IT892_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HAP3135816.1"
                     /translation="MKKWLVTIAALWLAGCSSGEINKNYYQLPVVQSGTQSTASQGNR
                     LLWVEQVTVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGW
                     VVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDG
                     YDEMVKVLAGVWSQEAASIAQEIKRLP"
     gene            17894..18061
                     /gene="rmf"
                     /locus_tag="IT892_002614"
     CDS             17894..18061
                     /gene="rmf"
                     /locus_tag="IT892_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome modulation factor"
                     /protein_id="HAP3135817.1"
                     /translation="MKRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSQWLGGW
                     REAMADRVVMA"
     gene            complement(18131..18649)
                     /gene="fabA"
                     /locus_tag="IT892_002615"
     CDS             complement(18131..18649)
                     /gene="fabA"
                     /locus_tag="IT892_002615"
                     /EC_number="4.2.1.59"
                     /EC_number="5.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014915875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-hydroxydecanoyl-ACP
                     dehydratase/trans-2-decenoyl-ACP isomerase"
                     /protein_id="HAP3135818.1"
                     /translation="MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMT
                     ETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEG
                     KGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASD
                     LKVGLFQDTSAF"
     gene            complement(18718..20478)
                     /locus_tag="IT892_002616"
     CDS             complement(18718..20478)
                     /locus_tag="IT892_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lon protease family protein"
                     /protein_id="HAP3135819.1"
                     /translation="MTIKKLAWRDLVPDTDSYQEIFAQPHLIDENDPLFSDTQPRLQF
                     ALEQLLHTRASSSFMLAKAPEESEYLNLIANAARTLQSDAGQLVGGHYEVSGHSIRLR
                     HAVSADDNFATLTQVVAADWVEAEQLFGCLRQFNGDITLQPGLVHQANGGILIISLRT
                     LLAQPLLWMRLKNIVNRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQE
                     MEPELSEQAIYSEFEDTLQIVDAESVTQWCRWVTFTARHNHLPAPGADAWPILIREAA
                     RYTGEQETLPLSPQWILRQCKEVASLCDGDTFSGEQLNLMLQQREWREGFLAERMQDE
                     ILQEQILIETEGERIGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFTDIERKAE
                     LGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISA
                     LADVPVNQSIAITGSVDQFGRAQPVGGLNEKIEGFFAICQQRELTGKQGVIIPTANVR
                     HLSLHSELVKAVEEGKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQASQ
                     QEGRHRFPWPLRWLNWFIPN"
     gene            20664..21116
                     /gene="matP"
                     /locus_tag="IT892_002617"
     CDS             20664..21116
                     /gene="matP"
                     /locus_tag="IT892_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ter protein MatP"
                     /protein_id="HAP3135820.1"
                     /translation="MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVL
                     LSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQ
                     RLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE"
     gene            complement(21192..22232)
                     /gene="ompA"
                     /locus_tag="IT892_002618"
     CDS             complement(21192..22232)
                     /gene="ompA"
                     /locus_tag="IT892_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpA"
                     /protein_id="HAP3135821.1"
                     /translation="MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGF
                     INNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTA
                     KLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRL
                     EYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLK
                     SDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSER
                     RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV
                     KGIKDVVTQPQA"
     gene            complement(22589..23098)
                     /gene="sulA"
                     /locus_tag="IT892_002619"
     CDS             complement(22589..23098)
                     /gene="sulA"
                     /locus_tag="IT892_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor SulA"
                     /protein_id="HAP3135822.1"
                     /translation="MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPM
                     MTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVES
                     MVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
                     LKIHSNLYH"
     gene            23317..23946
                     /gene="sxy"
                     /locus_tag="IT892_002620"
     CDS             23317..23946
                     /gene="sxy"
                     /locus_tag="IT892_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRP-S regulon transcriptional coactivator Sxy"
                     /protein_id="HAP3135823.1"
                     /translation="MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVS
                     DGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLNYYRVDESLWRNQLKLVRLSKYS
                     LDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
                     SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE"
     gene            complement(23909..26071)
                     /gene="yccS"
                     /locus_tag="IT892_002621"
     CDS             complement(23909..26071)
                     /gene="yccS"
                     /locus_tag="IT892_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309071.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01666 family membrane protein"
                     /protein_id="HAP3135824.1"
                     /translation="MAFMLSPLLKRYTWNSAWLYYARIFIALCGTTAFPWWLGDVKLT
                     IPLTLGMVAAALTDLDDRLAGRLRNLIITLFCFFIASASVELLFPWPWLFAIGLTLST
                     SGFILLGGLGQRYATIAFGALLIAIYTMLGTSLYEHWYQQPMYLLAGAVWYNVLTLIG
                     HLLFPVRPLQDNLARCYEQLARYLELKSRMFDPDIEDQSQAPLYDLALANGLLMATLN
                     QTKLSLLTRLRGDRGQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFR
                     FQRLMSMLGQACQQLSRCILLRQPYQHDPHFERAFTHIDAALERMRDNGAPADLLKTL
                     GFLLNNLRAIDAQLATIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTPESA
                     LFRHAVRMSLVLCFGYAIIQITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLV
                     GIAIGIPVLWFVPSLEGQLVLLVITGVLFFAFRNVQYAHATMFITLLVLLCFNLLGEG
                     FEVALPRVIDTLIGCAIAWAAVSYIWPDWQFRNLPRMLERATEANCRYLDAILEQYHQ
                     GRDNRLAYRIARRDAHNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYIS
                     ALGAHREQLTNPEILAFLDDAVCYVDDALHHQPADEERVNEALASLKQRMQQLEPRAD
                     SKEPLVVQQVGLLIALLPEIGRLQRQITQVPQETPVSA"
     gene            complement(26081..26527)
                     /locus_tag="IT892_002622"
     CDS             complement(26081..26527)
                     /locus_tag="IT892_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAP3135825.1"
                     /translation="MRTVLNILNFVLGGFATTLGWLLATLVSIVLIFTLPLTRSCWEI
                     TKLSLVPYGNEAIHVDELNPAGKNVLLNTGGTVLNIFWLIFFGWWLCLMHIATGIAQC
                     ISIIGIPVGIANFKIAAIALWPVGRRVVSVETAQAAREANARRRFE"
     gene            26650..28704
                     /gene="helD"
                     /locus_tag="IT892_002623"
     CDS             26650..28704
                     /gene="helD"
                     /locus_tag="IT892_002623"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase IV"
                     /protein_id="HAP3135826.1"
                     /translation="MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLL
                     AIHCKRGLVWGELEFVLPDEKVVRLHGTEWGETQRFYHHLDAHWRRWSGEMSEIASGV
                     LRQQLDLIATRTGENKWLTREQTSGVQQQIRQALSALPLPVNRLEEFDNCREAWRKCQ
                     AWLKDIESARLQHNQAYTEAMLTEYADFFRQVESSPLNPAQARAVVNGEHSLLVLAGA
                     GSGKTSVLVARAGWLLARGEASPEQILLLAFGRKAAEEMDERIRERLHTEDITARTFH
                     ALALHIIQQGSKKVPIVSKLENDTAARHELFIAEWRKQCSEKKAQAKGWRQWLTEEMQ
                     WSVPEGNFWDDEKLQRRLASRLDRWVSLMRMHGGAQAEMIASAPEEIRDLFSKRIKLM
                     APLLKAWKGALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALL
                     AALRKQNSQTTLFAVGDDWQAIYRFSGAQMSLTTAFHENFGEGERCDLDTTYRFNSRI
                     GEVANRFIQQNPGQLKKPLNSLTNGDKKAVTLLDESQLDALLDKLSGYAKPEERILIL
                     ARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQQADYVIIVGLQEGSDGFPAAARES
                     IMEEALLPPVEDFPDAEERRLMYVALTRARHRVWALFNKENPSPFVEILKNLDVPVAR
                     KP"
     gene            complement(28736..29194)
                     /gene="mgsA"
                     /locus_tag="IT892_002624"
     CDS             complement(28736..29194)
                     /gene="mgsA"
                     /locus_tag="IT892_002624"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415483.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAP3135827.1"
                     /translation="MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYA
                     TGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDV
                     KALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK"
     gene            complement(29290..29952)
                     /locus_tag="IT892_002625"
     CDS             complement(29290..29952)
                     /locus_tag="IT892_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2057 family protein"
                     /protein_id="HAP3135828.1"
                     /translation="MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLL
                     RGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLE
                     NEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASL
                     PQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQP
                     SS"
BASE COUNT         7739 a         7077 c         7884 g         7299 t
ORIGIN      
        1 catttaaagg cattatcata tttacgaaga gatcaggatg ataacgatga aaaaaagtgt
       61 attgacggcg tttataactg tggtatgtgc aacgtccagc gttatggctg ctgatgataa
      121 tgctatcacg gatggctcag taacatttaa tggtaaagtt attgctccag cttgtaccct
      181 ggtagctgcg acgaaagatt ccgtggtgac tttgccagat gttagtgcca cgaagttgca
      241 aaccaatggt caggtttctg gcgtgcaaat tgatgtgcca attgaattaa aagattgtga
      301 tactaccgta acaaaaaatg caacgttcac ctttaatggc actgcggata ctactcagat
      361 tacagcgttt gctaaccagg cctcatctga tgctgctaca aacgtggccc tgcaaatgta
      421 tatgaatgat ggtacaacgg ccatcacgcc agacacagaa accgggaaca ttttgttgca
      481 ggatggagat cagacgttga cttttaaagt tgattatatc gctacgggga aagcgacttc
      541 aggtaatgtg aatgcggtaa caaatttcca tattaactat tattaataga actcattaat
      601 tgttttatta attagtaccc ctccagtgtt ctggagggga tattcatatt ttttaagagt
      661 gactatttat gaaaacttgc ataacaaagg gaattgtgac cgtaagttta acggcaatat
      721 tactcagctg ctcatccgca tgggcggcag gtaaaggcgg gattggactt gcagcaacac
      781 gtcttgttta ttcagaaggt gaagagcaaa tttcaatggg tgtacgtaac accagtccgg
      841 atgttcctta tcttattcag tcatgggtga tgaccccaga taataaaaaa tcagcagact
      901 ttattattac accaccgcta tttgtgctga atccggcaaa tgagaatctg ttacgcatta
      961 tgtacattgg agcgccgttg gcgaaagaca gagaaaccct tttcttcact agcgtacggg
     1021 cagtcccttc aacaacgaag cggaaagagg gaaataccct gaagattgcc acacaaagcg
     1081 tcatcaaact tttctggcga ccaaaaggtt tagcgtatcc cttaggcgag gctccggcga
     1141 aactgcgttg cacttcgtca gctgacatgg ttacggtcag taacccaaca ccttatttca
     1201 ttaccctgac agacctgaaa ataggtggaa aagtagttaa aaatcaaatg atttccccct
     1261 ttgataaata ccaattttct ctgccaaagg gggccaaaaa tagcagcgta acgtatcgaa
     1321 ccatcaatga ctacggggcg gaaacgccgc aactcaactg taaatcgtaa gccgtcttca
     1381 gttaagagag cgagatgtat agaactcatc gacaacacag cctgttaagc tctggtggag
     1441 tgccatcgtt tattggtggg ctggtggtgt ttgtgtcggc agcgttcaat gcacaagctg
     1501 aaacctggtt cgatcctgct tttttcaaag atgatccctc aatggtggcc gatttgtctc
     1561 gtttcgaaaa aggacaaaaa ataacgccag gggtttatcg tgtcgatatt gttctgaatc
     1621 agacaattgt agatacgcgc aacgtcaatt ttgttgagat aacgccagag aaggggattg
     1681 ccgcctgttt gacgactgaa agcctggatg caatgggtgt taatactgat gcgtttccgg
     1741 cttttaaaca actggacaaa caagcgtgtg tgccattggc ggagattatt ccggatgcca
     1801 gcgtaacgtt taatgtgaat aaactccgtc tggaaatttc agtaccgcaa atcgccatca
     1861 aaagtaatgc ccgtggttat gtcccccctg aacgttggga tgaagggatc aacgcgctat
     1921 tactgggata ttcgtttagc ggggctaaca gtattcatag cagcgcagac agtgattctg
     1981 gcgacagcta ttttctgaat ttaaacagtg gcgttaattt aggcccatgg agattgcgca
     2041 acaattcaac atggagtcgt agtagtggcc aaaccgcaga atggaagaat ctcagcagct
     2101 atttgcaacg ggcggttatt cctctgaaag gcgaactgac cgtaggtgat gattatactg
     2161 caggcgattt tttcgatagt gtcagctttc gtggtgtgca gctggcgtca gatgacaaca
     2221 tgctgccaga cagcctgaaa gggtttgcgc ctgtggtgcg tggtatcgcc aaaagcaatg
     2281 cccagataac gattaagcaa aatggttaca ccatttacca aacttatgta tcgcctggtg
     2341 cttttgaaat tagtgatctc tattccacgt cgtcgagcgg tgatttgtta gttgaaatca
     2401 aagaagcgga cggcagcgtc aatagctaca gcgtaccgtt ctccagtgtg ccattactcc
     2461 agcgtcaggg gcgaatcaaa tacgcggtga cactggcgaa atacagaacc aatagtaatg
     2521 aacagcagga gagcaaattt gcccaggcca cgttgcagtg gggcggaccg tggggaacga
     2581 cctggtatgg tggtggacaa tatgctgaat attaccgtgc cgccatgttt ggtctgggat
     2641 ttaacctcgg cgatttcgga gcaatttcgt tcgatgcgac ccaggcgaag agtacgctag
     2701 cagatcaaag cgaacataaa ggtcagtcat atcgttttct gtatgccaaa acgctcaacc
     2761 acttgggcac taactttcaa ttgatgggct atcgctattc gacgtcgggt ttctacaccc
     2821 tttccgacac catgtataaa catatggatg gctacgaatt taatgacggt gatgatgaag
     2881 atacgccgat gtggtcgcgt tattacaatt tgttttacac caaacgtggc aaactgcagg
     2941 tcaatatctc ccagcaatta ggcgagtacg gttcgtttta tttaagtggt agccagcaaa
     3001 cttactggca tacggatcaa caggatcggc tattacagtt tggctacaac acgcaaatta
     3061 aagatctttc gctggggatt tcctggaact acagtaagtc ccgtggtcaa cctgatgctg
     3121 atcaggtgtt tgctctaaat ttttccctgc cgctcaatct gttgctcccc agaagtaatg
     3181 atagctatac caggaaaaaa aattacgcct ggatgacctc taacaccagt atcgataacg
     3241 aagggcacac tacacaaaac ctgggtttaa cggagacatt actcgatgac ggtaacctga
     3301 gctacagcgt gcaacaggga tataacagcg aggggaaaac ggctaatggt agcgccagca
     3361 tggattacaa aggggcgttt gcggatgccc gagtgggcta caactacagc gataacggca
     3421 gtcaacaaca actgaactac gctctttcag gcagtttagt tgcccattca cagggcatta
     3481 ccctggggca atcgctgggg gaaactaacg ttctgattgc agcaccaggc gcagagaata
     3541 ctcgtgtggc gaacagcacc gggctgaaaa ctgactggcg cggatatacc gttgttcctt
     3601 atgccacttc ttatcgggaa aatcgaatcg cacttgatgc ggcgtcgtta aaacgtaacg
     3661 tggatcttga aaatgcagta gtcaacgtgg ttcccaccaa aggggcgttg gttctggcgg
     3721 agttcaatgc ccatgcgggt gcaagggtat taatgaaaac atcaaagcag ggtataccgc
     3781 tgcgttttgg cgcgatagcg acgctggacg gcgtacaggc taatagcggc ataattgatg
     3841 atgatggctc gctctatatg gcgggtttac cggcgaaggg aacaataagc gtgcgctggg
     3901 gcgaagctcc cgatcaaatt tgtcatatca attacgagct taccgaacaa caaattaact
     3961 ctgcgattac gcgaatggat gccatatgca gataatcttt ggagaaaaat gcgtgtcatt
     4021 actacgacta ttttttgccg ccgtcttaat gctatggtgc gctcaaaccg ctgcttatag
     4081 cgggcagtgt catactactc aggggaatcc gtatattggc gtcaattttg gcgttaaaac
     4141 cctggaggaa gaagcaaata cggcaggggt agttaaagac aaattttatc agtggaacga
     4201 atcgaatgat tattatgttt cctgtgattg cgataaagac aatgtcagaa gtggccgatg
     4261 ggcattcgcc gcggattcac cgttagtcta tttaggcgac aactggtaca aaattaatga
     4321 ctatcttgcc gccaaagttt tattgcaggt taaaggcagt tctcctactg cggttccttt
     4381 cgaaaacgtg ggcacagggg gggatacccg atggcatatt tgcgaccctg gcggtcaacg
     4441 tttaggtggg cagggggcaa gcggtaatag cggtagcttt tccctgaaaa tattgcagcc
     4501 gttcgttggc tcggtcgtca ttcctcctat ggcgctggcg cgattatatg aatgctacaa
     4561 catacccgca ggtgattcct gcacgactac aggtacaccg gttttagtgt attacctgtc
     4621 tggtacgatc aattcacttg gctcatgttc cgtcaatgcc ggagagacaa ttgaagttga
     4681 tttaggtgat gtcttcgctg ccaatttccg tgttgtaggg cataaacctc ttggggccag
     4741 aacggcagaa cttgcaattc cagtcaggtg taacacggga aacgcgggat tagttaatgt
     4801 caacctgagt ctgacggcaa ccacagaccc cagctatccc caggcgatta agacgtcacg
     4861 tcctggcgtg ggcgtggtgg tgaccgatag ccagaacaac attatttccc ctgctggtgg
     4921 aacattaccg ctctctattc ctgatgatgc agacagtatc gcgcgaatga atgtctatcc
     4981 agtcagcacg acaggtgtac caccagaaac cgggcgattt gaagccacgg caacggtgag
     5041 aataaatttt gattaacgcg tgaacgtatg aagaaaaaaa cgatatttca gtgcgttatc
     5101 ttgttcttta gcattcttaa catccatgtc gggatggctg ggcctgaaca agttagtatg
     5161 catatttatg ggaatgtggt cgatcagggc tgtgatgtcg ccaccaaaag tgcattacaa
     5221 aatattcata ttggtgattt taatatcagt gattttcagg ccgcgaatac cgtaagcact
     5281 gctgctgatt tgaatatcga tatcaccggt tgtgccgctg gtattactgg cgcggacgtc
     5341 ctttttagcg gcgaggctga cacccttgcg ccgacactgc tcaaactaac tgacacaggc
     5401 ggaagcggtg gtatggcaac ggggattgcc gtgcaaattc ttgatgcgca aagtcagcaa
     5461 gaaatcccgc tcaatcaggt ccagcctctt acgcccttaa aagccgggga taacacactc
     5521 aaatatcaac ttcgttataa gtccacaaag gcgggagcaa cgggcggtaa tgcgacggcg
     5581 gttctctatt ttgatctggt ttaccagtga aggagtgatg ttgaaacgga taatctggat
     5641 tctgttctta ttgggattaa cgtggggctg tgagctattt gcccatgatg gcacggtcaa
     5701 cattagcgga tcgtttcgcc gtaatacatg cgtgctggca caggatagca agcaaatcaa
     5761 tgtgcagtta ggcgatgtct cgctgacacg tttttctcat gggaattatg gcccggagaa
     5821 atctttcatc attaatttgc aggattgcgg aacagatgtc agcacggttg acgtcacctt
     5881 ttcaggaacc cccgacggag tgcagagcga aatgttgtcc attgaaagtg gtacggatgc
     5941 agccagcggg ctggcaattg cgattctgga tgatgcgaag atattgattc cgcttaacca
     6001 ggcgagtaaa gactacagcc tacatagcgg taaggtgcca ttaacttttt atgcgcaatt
     6061 gcgacctgtc aatagcgatg tgcagtcggg taaagtgaat gccagcgcga catttgtact
     6121 tcattatgac taatacgtgg aacagattgg cgctcttgat tttcgccgtt ttatcgctgc
     6181 tggtggcggg tgaattgcag gcaggagtgg tggtcggcgg aacgcgattt atctttccgg
     6241 cagacagaga atcgatatct attttactga ctaataccag tcaggaatcc tggcttatta
     6301 acagtaaaat caaccgccca acgcgttggg ccggggggga agcgtcgaca gtgccagcac
     6361 cattactggc cgctccgcca cttattctcc tgaagcccgg tacgacaggc acgttgcgct
     6421 tgctgagaac ggaaagcgac atcttgcctg tggatcgcga aacgctattt gagttaagca
     6481 ttgccagcgt gccatccggc aaagttgaaa atcagagcgt aaaagtggcg atgcgctcgg
     6541 tatttaaact gttctggcga cccgaaggtt tgccgggcga cccgctggaa gcttatcaac
     6601 aattacgctg gacacggaat tcgcagggtg tacaactcac taacccaacg ccttattaca
     6661 ttaacctgat tcaggtgagt gtaaatggta aagcgttaag taatgtggga gttgtgccgc
     6721 ctaaaagcca gcgtcagaca agctggtgtc aggcaatcgc accgtgtcat gtcgcctggc
     6781 gggcgataaa tgattacggc gggttgagtg caaagaagga gcaaaatctg ccctgaaaca
     6841 ggttcggaaa acgtttgcgt tttttttgcc gcaggtcaat tcccttttgg tccgaactcg
     6901 cacataatac gcccccggtt tgcacaccgg gaatccagga gagttcatgt actacccctt
     6961 cgttcgtaaa gcccttttcc agctcgatcc agagcgcgct catgagttta cttttcagca
     7021 attacgccgt attacaggaa cgccgtttga agcactggtg cggcagaaag tgcctgcgaa
     7081 acctgttaac tgcatgggcc tgacgtttaa aaatccgctt ggtctggcag ccggtcttga
     7141 taaagacggg gagtgcattg acgcgttagg cgcgatggga tttggatcga tcgagatcgg
     7201 taccgtcacg ccacgtccac agccaggtaa tgacaagccg cgtctctttc gtctggtaga
     7261 tgccgaaggt ttgatcaacc gtatgggctt taataatctt ggcgttgata acctcgtaga
     7321 gaacgtaaaa aaggcccatt atgacggcgt cctgggtatt aacatcggca aaaataaaga
     7381 tacgccagtg gagcagggca aagatgacta tctgatttgt atggaaaaaa tctatgccta
     7441 tgcgggatat atcgccatca atatttcatc gccgaatacc ccaggattac gcacgctgca
     7501 atatggtgaa gcgctggatg atctcttaac cgcgattaaa aataagcaaa atgatttgca
     7561 agcgatgcac cataaatatg tgccgatcgc agtgaagatc gcgccggatc tttctgaaga
     7621 agaattgatc caggttgccg atagtttagt tcgccataat attgatggcg ttattgcaac
     7681 caataccaca ctcgatcgtt ctcttgttca gggaatgaaa aattgcgatc aaaccggtgg
     7741 cttaagtggt cgtccgcttc agttaaaaag caccgaaatt attcgccgct tgtcactgga
     7801 attaaacggt cgcttaccga tcatcggtgt tggcggcatc gactcggtta tcgctgcgcg
     7861 tgaaaagatt gctgcgggtg cctcactggt gcaaatttat tctggtttta tttttaaagg
     7921 tccgccgctg attaaagaaa tcgttaccca tatctaatta tttcttcgaa ttcctcttta
     7981 taagataatc agggctttat tttcagccct ggttgtttta tattcatcgc tgttgcttat
     8041 ttagacattt tgtactttta ttgttgaggt tattaagcga agcgacaatg gattgtgttg
     8101 ctgcggtttt atagggtagg ggagaggcag atgcgaatta aaccagacga taactggcgt
     8161 tggtattacg atgaagagca cgatcgaatg atgctcgatt tagccaatgg tatgctattt
     8221 cgctcacgtt ttgcgcgcaa gatgttgact ccagatgcct tttctcccgc aggcttttgc
     8281 gttgacgacg ccgcgctcta tttctctttt gaagaaaagt gccgcgattt taatttatct
     8341 aaagaacaaa aagccgaact ggtgctgaat gcactggtag caattcgcta tctcaaaccg
     8401 caaatgccga aaagctggca ttttgtttcc catggtgaaa tgtgggtgcc catgccgggc
     8461 gatgcggcct gcgtttggtt gagcgatact cacgagcagg tcaatttgct ggtcgttgaa
     8521 tctggcgaaa atgccgcact atgcctgctg gcacaaccct gcgttgttat tgcgggtcgc
     8581 gcgatgcagt tgggcgacgc cattaaaatc atgaacgaca ggctgaaacc gcaggttaat
     8641 gttgacagct tcagcctcga acaggcagtc taacgcgcca acttaagtgc agtcttcggt
     8701 acacagctac agcaaagaat ggtgccatca tcgcccattg ctgatttttt cagcggcgtg
     8761 acttcgcctt ctaaaagctg aacacggcaa cttccacaaa tgcccgcgcg gcaagaataa
     8821 gggatacgaa ttccctgatt ttctaattgc tccagcaaca cctgttggtt atttccacga
     8881 aatgcctgtc cctgccagtc aatatctaca tttgcgtccg gttgttgcgt gatgttggcg
     8941 gtatcatcag cggcagctgc gccgtaaatt tttgccggag ccgttgccag aatttccacc
     9001 tcatcgccaa cgcgaatcac gccgctatta cgggcaatta aattctgacc aaaatcgaca
     9061 tcgccgttat cctgggcagt gcggaaagat tgcaatgttt ttaatggttc gcctgccgga
     9121 tgtttttgcc ctttttctgg gctgacggtg gtgaaaatac agcggctaca aggtttaacc
     9181 acatcaaaca ccacatcacc aatgcgaatc actttccagc gatcttcttc ccaggctgac
     9241 gcgccggaaa ccaccagatt ggggcggaat tgctccattt ttacactggc cggacaacgt
     9301 tgttggagat aacgtaacga ggcttcgtta gcaagaaggt aaggatagcc atcagcaaat
     9361 gacagaggta cagtgttgtg gcgtttcacg cgccgggtca tttgtggccc cacccagcgt
     9421 aattgcactt cgcgggagaa aaattcactt agccatttgt tgatcgcgtc tggcgcaatt
     9481 cgcgcggtaa aatgtgtgcc ccaaacttcg gttggtgcgt cttgtgtggc gaaatcagca
     9541 aaacgaacat atgcgctact gccatctggt gcggtgagat gcaagccatc atgcacaggt
     9601 gaaggagtaa accgtaccat ctggggaaac tggcgagcgg taataaacgt accgtcaggt
     9661 tccgtgatca taaagatgcg atcgaaggcc agaccactga catctgccag agcatgtgta
     9721 agaccaatgc cgcgcatcga tttaacagga tgaataaaaa gccggattaa tgtcgccacg
     9781 gtgcggtcct caaatgaaaa taagccctca actttatgac atgacgcgct tattagctat
     9841 aatgcgcaac aattttctta gcgcctgtcc cattaggcta ttttatttgt cagtttggcc
     9901 ctgggttatg ctcgaaatcc tcacgtactt gtgtacgctc cggtttctcc gcgctgtcca
     9961 tgtccagact gactgcaaca attacgccta ctgcggtagg ctcttagagt aaaagtgacg
    10021 atatgaattc tctgtttgcc agtacggccc gtgggctgga agagctgtta aaaactgaac
    10081 tggaaaacct gggggccgtt gaatgccagg tggttcaggg tggggtccat ttcaagggcg
    10141 acacacggct tgtttaccag agcctgatgt ggagccgcct ggcctcgcgt attatgttgc
    10201 cgctgggcga gtgtaaggtt tacagcgatt tagacctcta tctcggtgtt caggcgatca
    10261 actggacaga gatgtttaat cctggcgcga ccttcgctgt ccacttcagt ggtttgaatg
    10321 acaccatccg caacagtcag tacggcgcga tgaaagtgaa agacgcgatc gtcgatgctt
    10381 tcacgcggaa aaatctgccg cgtccaaatg ttgatcgcga tgcgccggat atccgcgtta
    10441 acgtctggct gcataaagaa accgccagta tcgctcttga tctgagtggt gatggtttac
    10501 atctgcgtgg ctatcgcgat cgtgctggta ttgcgccgat caaagaaacc ctggcagccg
    10561 ctattgtgat gcgatccggc tggcagccag gaacaccgct gctcgatccg atgtgtggtt
    10621 ccggtacgtt gctgattgaa gcagcgatgc tggcgaccga tcgcgcacca ggcttgcacc
    10681 gtgggcgttg gggctttagc ggctgggcgc agcatgatga agctatctgg caggaagtga
    10741 aagcggaagc gcaaactcgc gcccgtaaag gcctggctga gtatagctct catttttacg
    10801 gttcggacag cgacgcacgg gtgattcaac gtgcacgcac taacgcccgt cttgcgggga
    10861 ttggtgaact gatcaccttt gaggtgaaag atgtcgcgca actgaccaat ccgctgccga
    10921 aagggccgta cggcacagtg ttgagcaacc cgccatacgg ggaacgtctg gacagcgaac
    10981 cggcgctgat tgcgctgcat agcctgctgg gtcggatcat gaaaaaccag tttggtggct
    11041 ggaatctctc tttgtttagt gcctcgccgg atctgctaag ctgcttgcag ctgcgtgcag
    11101 acaaacagta caaggcgaaa aacggcccgc tggactgcgt acagaaaaat taccacgttg
    11161 ccgaaagcac tccagacagc aaaccggcga tggtagcgga agactacacc aaccgcctgc
    11221 gtaagaacct caaaaaattc gagaagtggg ctcgccagga agggattgaa tgttaccgcc
    11281 tgtatgacgc cgatctgcca gaatataacg ttgccgttga ccgttatgcc gactgggtgg
    11341 tggtgcagga gtatgcgccg ccaaaaacta ttgatgctca caaagcgcgt cagcgtctgt
    11401 tcgatattat cgctgcaacc atttcggtac tggggattgc gccaaacaaa ctggtgctga
    11461 aaacccgtga acgccagaag ggcaaaaacc aataccagaa actgggcgag aagggcgagt
    11521 ttcttgaagt taccgaatat aacgctcact tgtgggtgaa cctgacggat tatctcgata
    11581 ctggtctgtt cctcgatcac cgcatcgccc gtcgtatgct cggtcagatg agcaaaggca
    11641 aagatttcct caacctgttc tcttataccg gcagcgccac cgtgcatgcg ggattaggcg
    11701 gtgcacgcag caccaccacc gtggatatgt cgcgtactta tctggaatgg gcagaacgca
    11761 acctgcgtct gaatggcctg accgggcgtg cgcatcgcct gattcaggcc gattgcctgg
    11821 cgtggctgcg tgaggcaaat gaacagttcg atctgatctt tatcgatccg ccaaccttct
    11881 ctaactcaaa acgaatggaa gatgcgtttg atgttcagcg cgatcatctg gcgctgatga
    11941 aagatttgaa acgtctgctg cgtgcaggtg ggacgatcat gttctcgaac aacaaacgtg
    12001 gcttccgtat ggatctcgac ggcctggcaa aactgggact gaaagcacaa gaaattacgc
    12061 aaaaaacgct ctcccaggat ttcgcccgta accgccagat ccacaactgc tggctgatta
    12121 ccgcagcctg aaaggaatag taatgtcatt aatcagtatg catggcgcat ggctgtcgtt
    12181 cagcgacgcg ccgcttctcg ataacgcaga actgcatatc gaagataacg aacgtgtttg
    12241 tctggtgggc cgcaacggcg caggcaaatc gacgttaatg aaaatcctca accgtgaaca
    12301 agggctggat gacggtcgca ttatttacga gcaagatttg attgtagcgc gtctgcaaca
    12361 ggatccgccg cgtaacgttg agggtagcgt ttatgatttc gttgccgaag gcattgaaga
    12421 acaagcggaa tatctgaaac gctatcacga tatttcgcgc ctggtgatga acgacccgag
    12481 cgagaaaaat ctcaacgaac tggcgaaggt tcaggaacag ctggatcacc acaacctgtg
    12541 gcagctggaa aaccgcatca acgaagtgct ggcgcaactg gggttagatc ctaacgttgc
    12601 gctgtcgtcg ctttccggcg gctggttgcg taaagcggca ttaggacgcg cgctggtgag
    12661 taatccgcgc gtgctgttgc ttgatgaacc gacaaaccac ctggatattg aaaccatcga
    12721 ctggctggaa gggtttttga aaactttcaa cgggacgatt attttcatct cccacgaccg
    12781 ttcgtttatc cgcaatatgg cgacgcgcat tgttgatctc gatcgcggca agctggtgac
    12841 ctatccaggg aattacgacc agtacctgct ggaaaaagaa gaagccctgc gcgtggaaga
    12901 attacaaaat gccgagttcg atcgcaaact ggcgcaggaa gaggtgtgga tccgccaggg
    12961 gatcaaagca cgccgtaccc gtaatgaagg ccgcgtacgc gccctgaaag cgatgcgtcg
    13021 cgaacgtggt gaacgtcgcg aagtgatggg taccgcaaag atgcaggtgg aagaggccag
    13081 ccgctccggt aaaatcgttt tcgaaatgga agacgtttgc taccaggtta acggtaagca
    13141 actggtgaaa gatttttctg cccaggttct acgtggcgac aaaattgccc tgattggtcc
    13201 gaatgggtgc ggcaaaacca cgctgctaaa actgatgctc ggtcagcttc aagcggacag
    13261 cgggcgtatt cacgttggca ccaaactgga agtggcttat ttcgatcagc accgcgcgga
    13321 actggatccc gataaaacgg tgatggataa ccttgccgaa ggtaagcaag aggtgatggt
    13381 taacggcaag ccacgccacg tattgggcta tttgcaggac tttctgttcc atccgaaacg
    13441 ggcgatgacg ccggtacgtg cgctttctgg cggtgagcgg aaccgcttgc tgctggcgcg
    13501 tttgttcctc aaaccaagca acttattgat tcttgacgaa ccgaccaacg atcttgatgt
    13561 cgaaacgctg gaactgctgg aagaactgat cgacagctat cagggcacgg tattgctggt
    13621 tagccacgat cgtcagtttg tcgataacac cgttacagaa tgttggatct tcgaaggcgg
    13681 cggtaaaatt ggtcgttatg tcggcggtta tcatgatgcc cgtggtcagc aagagcagta
    13741 tgtggcgctc aaacagcctg cggtgaaaaa aaccgaagaa gccgccgcgg caaaagcaga
    13801 aactgtaaaa cgcagcagta gcaaactaag ctataaattg cagcgcgaac tggagcagct
    13861 accgcaattg ctcgaagatc tggaggcgaa gctggaagcc ctacagacgc aagtggcgga
    13921 tgcttccttc ttcagtcagc cgcatgagca gacgcaaaaa gtgcttgctg atatggctgc
    13981 tgcagagcag gagctggagc aagcctttga acgctgggag tatcttgaag cgttaaaaaa
    14041 tggtggctga tcgcaaaata gtcgatttaa acagagacag ctgacaacgg taaaattgcc
    14101 tgatgaactg ggtttatcag gcatgaaaac caacactttg ttagtcatct gtaaaatagc
    14161 gcatcattaa ggagtaccaa tgtgcgaaca tcatcatgcc gcgaagcaca tcctgtgctc
    14221 gcagtgtgac atgctggtgg cgttaccgcg ccttgagcat ggtcagaaag cggcatgtcc
    14281 ccggtgtggc acaacgttaa ccgtggcgtg ggatgcccct cggcagcgtc ccaccgccta
    14341 tgcgttggct gcactgttca tgctgttgct gtccaacttg tttccttttg tgaatatgaa
    14401 cgttgcagga gttaccagtg aaattacatt actggaaatt cccggcgtgc ttttttctga
    14461 ggactacgcc agcctcggca cctttttcct gttgtttgtg caactggttc ccgcgttttg
    14521 tctgataacc attctgttac tggtgaatcg cgcggaatta ccggtccgtt taaaagagca
    14581 actggcacgg gtgctttttc aactcaaaac ctggggaatg gcggagattt tcctcgcggg
    14641 tgtgctggtc agtttcgtta aactgatggc ttacggcagc attggggtag gcagcagctt
    14701 tctcccctgg tgtttatttt gtgtcctgca actgcgcgct tttcagtgcg ttgatcgtcg
    14761 ctggttatgg gacgacatcg ccccgatgcc agaactgcgc cagccgctaa aaccaggcgt
    14821 cacggggata cgtcaggggc tgcgttcgtg ctcctgttgt acggcaatcc ttcctgctga
    14881 tgaacccgtg tgcccgcgtt gtagtaccaa agggtacgtt cggcgtagaa acagcctgca
    14941 gtggacactc gcgctgcttg taacgtccat catgctgtat cttccggcta atattttgcc
    15001 catcatggtg acggatttat taggctcgaa gatgccgtcg acgattctcg ctggggtcat
    15061 tctgttatgg agcgaaggct cttatcccgt cgctgcggtg atctttctgg ccagtattat
    15121 ggtgccaacg ttaaagatga tcgccatcgc gtggctgtgt tgggatgcca aagggcatgg
    15181 caagcgcgac agtgaaagaa tgcatttgat ttatgaagtt gttgagtttg taggccgctg
    15241 gtcgatgatt gacgttttcg ttatcgcggt gctctcggcg ctggtgcgta tgggaggttt
    15301 aatgagtatt tatccggcaa tgggtgcatt aatgtttgct ttagtcgtca taatgacaat
    15361 gttttctgct atgacgtttg acccgcgttt gtcgtgggat cgtcaacctg aatcagagca
    15421 tgaggagtcc tgacagtatg gaatctaata atggggaagc caaaatccag aaagtgaaga
    15481 actggtctcc cgtgtggata tttcctatcg tcacggcgct cattggggcc tgggttcttt
    15541 tttatcatta cagccatcag ggaccggaag tgaccctgat caccgcgaat gcggaaggaa
    15601 ttgaaggtgg caaaaccacc attaaaagcc gtagcgttga cgtcggcgtg gttgaaagcg
    15661 ccacactggc tgatgatttg acgcacgttg aaatcaaagc gcggctgaat tccggtatgg
    15721 aaaaattgct gcataaagac accgtctttt gggtggtgaa accgcagatt ggtcgcgaag
    15781 ggattagcgg cctgggaacg ctgctgtctg gagtttatat cgaactgcag ccaggcgcga
    15841 aaggcagcaa aatggataaa tacgatttgc tggactcgcc accgttggcc ccgcctgatg
    15901 cgaaaggtat ccgtgtgatt ctcgatagca aaaaagccgg gcagctctcg ccaggagatc
    15961 cggtgctgtt ccgtggctat cgggtaggtt cggttgaaac cagcaccttc gatacacaaa
    16021 aacgcaatat cagctatcaa ctgttcatca atgcacctta tgaccgactg gtgaccaaca
    16081 atgttcgctt ctggaaagat agtggcattg cggttgatct gacgtcagca gggatgcgtg
    16141 tggagatggg ctcattgaca acgctgctga gtggcggtgt cagctttgat gtgccggaag
    16201 gtctggattt agggcagcca gtggcaccga aaacagcttt cgttttgtat gatgatcaga
    16261 agagcattca ggattcgttg tacaccgatc acattgatta tctgatgttc tttaaagatt
    16321 cggtacgcgg tctgcaaccg ggagctccgg tagagttccg gggtattcgc ctgggtaccg
    16381 taagcaaagt gccattcttt gcgccgaata tgcgtcagac atttaacgat gattaccgta
    16441 ttccggtact gattcgtatc gagccagagc ggctgaaaat gcagcttggc gaaaatgcgg
    16501 atgttgttga gcaccttggc gaattgttga aacgtggttt acgcggatcg ctgaaaaccg
    16561 gaaacctggt cactggtgca ctgtatgttg atctcgattt ctatccaaat acgcctgcaa
    16621 taaccggtat tcgtgaattt aatggttatc agattatccc gaccgttagc ggcggcctgg
    16681 cgcaaatcca gcaacgactg atggaagcgt tggataagat caacaaactg ccattgaatc
    16741 cgatgattga acaggcaacc agtacgcttt ctgaaagtca gcgcacaatg aaaaacctgc
    16801 aaacgacgct ggatagcatg aacaagatcc tcgctagcca gtcgatgcag cagttgccga
    16861 cggatatgca gtcaacgttg cgtgaattga atcgcagcat gcagggcttc cagcctggct
    16921 ccgcagccta caacaagatg gtggcggata tgcagcgcct tgatcaggtg ttgcgagaac
    16981 tgcaaccggt gctgaaaacg ctcaatgaga agagtaacgc gctggtattt gaagcgaagg
    17041 acaaaaaaga tccagagccg aagagggcga aacaatgaaa aagtggctag tgacgattgc
    17101 agcactgtgg ctggccggat gcagctccgg cgaaattaat aaaaactatt accagttacc
    17161 tgtggtgcag agcggtacac aaagtaccgc cagccagggc aatcgtctgt tatgggtaga
    17221 gcaggtcact gttcctgact atctggcggg gaatggtgtg gtttatcaaa ccagtgatgt
    17281 gaagtatgtg attgccaaca acaacttgtg ggccagcccg ttggatcaac agttgcgcaa
    17341 caccctggtt gccaacctga gtacgcaact gcccggctgg gtggttgcct cccagcctct
    17401 gggaagcgcc caggacacgc tcaatgttac cgtaacggag tttaacggtc gctatgatgg
    17461 caaggtcatt gtcagtggtg agtggctgtt gaaccaccag ggacaactga tcaaacgtcc
    17521 gttccgtctg gaaggagtgc aaactcagga tggttacgat gagatggtta aagtgctggc
    17581 cggtgtctgg agtcaggaag ccgcttctat tgcacaagag ataaagcgtc taccttaatt
    17641 ataaagattt gtaaatataa ccgtctccgg tatgttgcct gaggcggttt ttttgtctct
    17701 aacgtgcgga aaaatttgtt cctcttcaca ttttttgtac aaccgacatg cccgtgtagc
    17761 tcacaaatat gacagtggcg tgaattttgc gcattgacgg cagttatgat tcgcggtatt
    17821 gcttaactgt gattgcacat ttagtaatca ctgttttctt ttccaccaga aaccagtatg
    17881 agggaaacga ggcatgaaga gacaaaaacg agatcgcctg gaacgggcac atcaacgtgg
    17941 ttatcaggcc ggcatcgccg gacgctcaaa agaaatgtgt ccctatcaga cgctgaatca
    18001 aaggtcacaa tggctgggag gctggcgaga agccatggcg gacagggtag taatggcctg
    18061 attctgtctc tttaaaaaga aacctccgca ttgcggaggt ttcgcctttt gatactctgt
    18121 ctgattataa tcagaaggca gacgtatcct ggaacagacc gactttcagg tcgctggcgg
    18181 tatagatcag acgaccatca accagcactt cgccatccgc caggcccata atcagacgac
    18241 ggttaacaat gcgtttaaag tgaatacggt aggtcacttt tttcgctgtc ggcagtacct
    18301 gaccagtgaa tttcacttcg ccaacgccca gcgcgcggcc tttaccttcg ccgcccagcc
    18361 agccgaggta gaaccctacc agctgccaca ttgcgtccag gcccaggcat cccggcataa
    18421 ccggatcgcc aataaagtgg catccgaaga accacagatc cggattgata tccagttctg
    18481 cttcaacata ccctttgtcg aagttaccac ccgtttcggt cattttgacc acacggtcca
    18541 tcatcagcat gttcggtgct ggcaattgcg ggcctttagc gccaaacagt tcaccgcgac
    18601 cagaggcaag aaggtcttct tttgtatagg attcgcgttt atctaccatg ttctctgtaa
    18661 gccttatttt attgaagcac gcaggatagc taacacgtgt acgctgaaca agtccgatca
    18721 gttcggaata aaccagttca gccaacgtaa tggccatgga aaacggtgac gtccttcctg
    18781 ttgcgatgct tgcgcgatac gttcctggat ggtttgcatc agcgtcgttt ggccttcgcc
    18841 atcccacacc agatttaata ataacggcag tgcgtcagtc acatcgtcta ctgcccagat
    18901 ggtgaatttg ccttcttcta ccgctttcac cagttcactg tgaagactta aatggcgaac
    18961 gttagctgtg gggataatga caccttgttt cccggttaac tcacgttgct ggcaaatagc
    19021 aaagaagcct tcgattttct catttaaacc accgaccggc tgggcgcgac cgaactgatc
    19081 gactgaacct gtgatagcga tactctgatt caccggcaca tcggcgaggg cgcttatcag
    19141 ggcgcagagt tcagccatcg aggcactatc tccatcaact tcactgtatg actgctcaaa
    19201 tgtcagcgat gctgagaagg ggatctgttg ctcaagctgt agttccgaca tcaggaacgc
    19261 ttgcatgatc atcatccctt tcgcatggat attgccgcca agctccgctt tgcgttcgat
    19321 gtcggtgaat tcaccatcgc caatatgcac aacgcagcta atgcgagaag gttcgccaaa
    19381 agcgcgtgga tgacccggaa attcaatgac cgaaagggcg ttaatttgcc cgatgcgttc
    19441 gccttcggtt tcaatcagga tttgctcctg aaggatctca tcctgcatac gttcagcgag
    19501 gaaaccttcg cgccattcac gctgctgcag cattaagttt agctgctcgc cggagaaggt
    19561 gtcgccatca cacagggagg cgacctcttt acactggcgg aggatccact gcgggctaag
    19621 cggaagtgtt tcttgttcac cggtgtagcg tgctgcttcg cggataagta tcggccaggc
    19681 atccgctccc ggtgcaggta agtgattatg tctggcggta aatgtcaccc agcgacacca
    19741 ctgggttact gactccgcat cgacaatctg cagagtatct tcaaattcgc tataaatagc
    19801 ctgctctgaa agctctggct ccatctcctg gaaatcagcc aatgattcgc gttcgcctac
    19861 cagaatgact ttcagcttca atggcatcga aggcacagag acggggagag ggcgcgactc
    19921 atcaaacgca acccagtcaa aacgctcgcg gttaacgata tttttcagcc gcatccacag
    19981 cagaggttgc gccagcagtg tacgcaaaga gataatgaga ataccgccat ttgcctgatg
    20041 caccagacca ggctgcaggg taatgtcgcc attaaactgg cgcaggcagc caaagagttg
    20101 ctccgcttct acccagtcgg cagcgacaac ttgcgttaaa gtcgcaaaat tatcatctgc
    20161 actcactgcg tgacgtaagc ggatggagtg gccggaaacc tcatagtgac cgcccaccag
    20221 ttggcctgca tcgctttgta gcgtacgcgc ggcattggca ataagattca gatactcaga
    20281 ctcttccggg gccttcgcca gcataaaaga ggaggatgct cgcgtatgca gcaactgctc
    20341 cagcgcaaat tgcagccgcg gttgagtatc actgaataaa ggatcgtttt cgtcaatcaa
    20401 atgtggctga gcaaatattt cctgatagct atcggtatca ggaaccaggt cacgccatgc
    20461 aagtttctta atggtcaaag ttgatgtttt ttagtctgtt gtcaaagccg cgattatacc
    20521 gtaaccggca ctacagcaca cgtagaaagc accgacaata ctcctggcat gggcgttaaa
    20581 gctcacagga tggagattct tttcttcact ggcctaaaaa gctgatattc tgtaaagagt
    20641 tacacggtaa cattgagatc gctatgaaat atcaacaact tgaaaatctt gaaagcggtt
    20701 ggaaatggaa gtatctggtt aagaagcatc gcgaagggga gttaatcacc cgttacatag
    20761 aagccagtgc cgcccaggaa gccgtcgatg tgttgctctc gctggaaaat gaacccgtgc
    20821 tggtaaatgg ctggattgac aagcatatga atccggaact ggtcaatcgc atgaagcaaa
    20881 ccattcgggc aagacgaaag cgccatttta atgcggaaca ccagcatacg cgcaaaaaat
    20941 cgatcgatct ggaatttatt gtctggcaac gtctggctgg tcttgcgcag cgtcgcggta
    21001 aaacgctttc tgaaacgatt gttcagctga ttgaagatgc ggaaaacaaa gagaaatacg
    21061 cgaataaaat gtcttctctg aagcaggatc tgcaggcatt gctgggtaag gaataactga
    21121 cgaaagtcag ttcaatttac taaaggcaaa aaaaaccccg cagcagcggg gtttttctac
    21181 cagacgagaa cttaagcctg cggctgagtt acaacgtctt tgataccttt aacttcgatc
    21241 tctacgcgac gatccggagc caggcagtcg atcagtgcag cacgctgttt cacgttgtca
    21301 caggtgttgc cagtaaccgg gttggattcg cccataccac gtgcggagat cttgtctgcc
    21361 gggatacctt tggagatcag gtaatcaaca acagactgag cacggcgctc ggacagaccc
    21421 tggttgtaag cgtcagaacc gatgcggtcg gtgtaaccca gaacaactac ggaaccgtct
    21481 ttcggatcca ggttgctcag ctggctgtac agctgatcca gagcagcctg accttccggt
    21541 ttcagggttg ctttgttgaa gttgaacaga acgtcagact tcagagtgaa gtgcttggtc
    21601 tgtacttccg gtgccggagc tggagccgga gcaactactg gagctgcttc gccctgaccg
    21661 aaacggtagg aaacacccag gctcagcatg ccgttgtccg gacgagtgcc gatggtgtgt
    21721 gcgtcaccga tgttgttggt ccactggtat tccagacggg tagcgatttc aggagtgatc
    21781 gcgtactcaa caccgccagc gaagaccgga gaaacgccgg tgtcgtggtt tttaccataa
    21841 acgttggatt tagtgtctgc acgccatacc atgccaccca gacgagtgta gatgtccagg
    21901 tcgtcagtga ttgggtaacc cagtttagcg gtcagttgaa cgccctgagc tttgtatgca
    21961 ccgttttcaa cgctgccttt gtacggcata cgacctaacc agtcgtaacc catttcaaag
    22021 ccaacatacg ggttaacctg gtaaccacca aaagcaccag cgcccagttg gttttcatgg
    22081 gtcgggccat tgttgttgat gaaaccagtg tcatggtact gggaccagcc cagtttagca
    22141 ccagtgtacc aggtgttatc tttcggagcg gcctgcgcta cggtagcgaa accagccagt
    22201 gccactgcaa tcgcgatagc tgtctttttc attttttgcg cctcgttatc atccaaaata
    22261 cgccatgaat atctccaacg agataacacg gttaaatcct tcaccggggg atctgctcaa
    22321 tattaactct accgatatct tcggcttatg ccgagcaccc ctggcgatgt aaagtctaca
    22381 acgtagttga aaacttacaa gtgtgaactc cgtcaggcat atgaaaaaaa agtcttgtat
    22441 aaggtatgtt taatcttttt tgtcagcgac aatttacaga agagaatcgc ggaaaccgct
    22501 tcagacaagc ctccgcaagg aaaattagtc acgactgaaa gcattggctg ggcgacaaaa
    22561 aaagttccag gattaatcct aaatttactt aatgatacaa attagagtga atttttagcc
    22621 cggaaagttg tctcgtggcg tgagaggatg cgcttaccgg acgcataata aaccccatag
    22681 cgttaccttc atttgccgca tcaacaagtt cagcatgctc ttcttcagtc aaatcatctg
    22741 ccaaccaacc gatcaccaca ctgtaattgc ccgtgcgtaa agcgcgaacc attgactcca
    22801 cagtgtggca aggggagagc tggctaatct gcattacttt cgttaagggt agcccagatg
    22861 cctgaaccca ttcccgactc agtttttgtt gcggtgttaa ccagagttgc cagcgcgatt
    22921 gctgaccgag ttgctgtaac aatggcaaca gtagaagttg cgtcatcatg ggctgatctt
    22981 cgcgatagac aacttcactg ataagcccgg ctgtagtgtt ttccgtagag acacgcgcaa
    23041 ttttacttgc tgcggatgag aacgacgaag aacgatgtgc atagcctgaa gtgtacataa
    23101 tcaatccagc ccctgtgagt tactgtatgg atgtacagca catccagtga caacaaagat
    23161 caaccctatt ttcggaaaga gcctcgcaaa ttttgtcgtt ggtgacggga aaacataaat
    23221 taatcttgcc ccttaagaat aagttgccta ttttcgtagt taacggatcc gttaatgtga
    23281 atcattcttt tatgttatga ttttaaaagg aattttatga aaagcctctc ctataagcgg
    23341 atctataaat cacaagaata cctggcaacg ttgggcacaa ttgaataccg atcattgttt
    23401 ggcagttaca gcctgaccgt tgacgacacg gtgtttgcga tggtttctga tggtgagttg
    23461 tatcttcggg cttgtgagca aagtgcacag tactgtgtaa aacatccgcc tgtctggctg
    23521 acatataaaa agtgtggccg atccgttacc ctcaattact atcgggttga tgaaagtcta
    23581 tggcgaaatc aactgaagct ggtgcgtctg tcgaaatatt ctctcgatgc agcgctgaaa
    23641 gagaaaagca cgcgcaatac ccgggaaaga ctgaaagatt tgcccaatat gtcttttcat
    23701 ctggaagcga ttctcgggga ggtggggatt aaggatgtac gggcgttacg tatacttggg
    23761 gcaaaaatgt gttggttgcg actgcggcag caaaacagtc tggtgacaga aaagattctg
    23821 tttatgcttg aaggtgccat tatcggcatt catgaagctg cgctcccggt ggcacgccgc
    23881 caggagcttg cagaatgggc tgactctctt acgccgaaac aggagtttcc tgcggaactt
    23941 gagtaatctg gcgttgcaga cgaccaatct caggcagtaa tgcaatcaat aatccaactt
    24001 gttgtacgac cagaggttct ttgctgtctg cccgtggttc aagttgctgc atccgctgtt
    24061 tcaggctagc taatgcctca ttgacgcgtt cttcatcagc aggttgatga tgtaacgcgt
    24121 catcaacata gcaaactgcg tcatcaagaa acgccagaat ttcaggatta gttaactgct
    24181 cccggtgagc accgagggct gagatatagc tggtaaacgt atggttaagg cacagcaacc
    24241 gaaacgcggc ttcgcgaatt tgcggggtaa cgttcggctc gctggacata tttgatacca
    24301 ccgacgccag ctcagcatca cggttgtgtg catcgcggcg ggcaatacga tacgccagac
    24361 ggttatcacg cccctgatgg tattgctcca gtatggcatc gagataccga cagttggcct
    24421 ctgtggcgcg ttcgagcatg cgcggcagat tgcgaaactg ccagtcaggc cagatgtagc
    24481 tcactgccgc ccacgcaatg gcacaaccaa tcagcgtatc gattacgcga ggtaacgcta
    24541 cttcaaaacc ttcacccagt aagttaaaac acagtagcac caaaagtgtg atgaacatcg
    24601 ttgcatgagc gtattgcacg ttacggaagg caaaaaagag cacgccggta ataaccagca
    24661 gcaccagctg cccttccagt gatggcacaa accacagcac aggaatgcca atggcgatac
    24721 ctaccagcgt accaataatc cttaacttca ggcggtggcg cgtggcgtta tagtttggct
    24781 ggcagacaaa caaacttgtc agcaagatcc aatacccgtg atgcattccg gttatctgaa
    24841 tgatggcgta gccgaagcac aacaccagcg acattcttac cgcatgacgg aagagggcgg
    24901 attccggcgt gaagtgacgg ctaagacgca gccagatatc actcaacccg tgcgggctgt
    24961 catcagcgag ctcattttcg tcattattat ggggtagtgc ctgggcctgt tctgattcaa
    25021 ttgttgccag ttgggcatca atggcgcgta aattgttcag caaaaatccc agtgttttga
    25081 gtaaatcggc gggtgcgccg ttatcgcgca tccgctccag cgcagcatca atatgcgtaa
    25141 aagcgcgctc aaaatgcgga tcatgttgat aaggctgacg caacaaaata cagcgtgaca
    25201 gttgctggca cgcctggccc agcatcgaca tcagccgctg aaaacggaac agcacgtcgc
    25261 tgtggcgaaa atgttcacgc aatgtttgat actgaatatg agaagagctg gcacgctcgt
    25321 gaatatcctg tgcgacaaag taataatgca gcgtgcgacg cgttccccgt tgaccacgat
    25381 cgccacgtaa gcgggtcagc agcgagagtt tcgtctgatt caatgtcgcc atcagcagac
    25441 cgttggcgag agccaaatcg tacagcggtg cctggctttg atcttcaata tcaggatcaa
    25501 acatgcgcga cttgagctca agataacgcg ccagttgttc atagcaacgc gccaggttgt
    25561 cctgcagcgg gcggaccggg aacagcagat gaccaataag tgtcaggacg ttgtaccaga
    25621 cggcaccggc cagcagatac atcggctgct gataccagtg ctcatacagt gatgttccca
    25681 acatagtgta aatggcgatc agcaatgcac cgaaggcaat tgttgcatag cgttgaccca
    25741 gaccgccgag caaaatgaag ccgctggtag agagcgttaa gccaatcgca aatagccagg
    25801 gccagggaaa cagcaattct actgaggccg aggcgataaa aaagcagaac agcgtaatga
    25861 tgaggttacg caaacgtccc gccagtcggt catcgagatc ggtcagcgcc gctgccacca
    25921 tccccagcgt tagcggaatc gtcagtttta catcacccag ccaccacgga aacgctgtgg
    25981 ttccacaaag cgcaataaaa atacgcgcgt aatacagcca ggcgctgttc caggtatagc
    26041 gtttgagcaa aggacttagc ataaaggcca tattagtgga ttattcaaaa cgacgacgtg
    26101 cattggcttc acgcgcagct tgcgctgttt ctaccgatac cacgcgacga ccaaccggcc
    26161 atagtgcaat agcggcaatt ttaaagttcg caatgccgac aggaatgcca atgattgaaa
    26221 tacattgtgc gatgcccgtt gcaatgtgca tcaggcataa ccaccagcca aagaaaatca
    26281 gccagaaaat attcaatacc gtaccgccag tattcagcag cacatttttg ccagccgggt
    26341 tcagttcatc gacatgaata gcttcattgc cataaggcac cagagacagt ttagtgatct
    26401 cccagcagga tcgtgtcagc ggtaaggtaa aaatcagcac aatactgacc agagtcgcca
    26461 acagccagcc cagagtggtg gcaaatccgc caagcacaaa gttcagaatg ttcaaaacgg
    26521 tacgcataaa acctcgcttt actgtggttt tcagtaatgg gcggcaattg taacgttttt
    26581 ttgggctgga gcacgttttc tctgacggtt acactgataa gaaataattt cgtgtggatc
    26641 tacagagtca tggaactgaa agcgacaacg cttggaaaac gtctggcaca gcacccttac
    26701 gatcgggcgg tgatcctcaa tgccgggatt aaagtctccg gcgatcgcca cgaatacctt
    26761 attcctttca atcaattact ggcgattcac tgtaagcgcg gtctggtatg gggcgagctg
    26821 gaatttgtac tgccggacga aaaagtggtg cgtctgcacg gcaccgaatg gggcgagacg
    26881 cagcgttttt accatcatct tgatgctcac tggcggcggt ggagtggcga gatgagcgaa
    26941 attgcgtctg gtgttttacg ccagcaactg gatttgattg ccacgcgcac tggggaaaat
    27001 aaatggctga cgcgtgagca aacctctggc gtgcagcaac aaatccgcca ggctttgtcg
    27061 gcgttgccgt tgccggttaa ccgactggaa gaattcgata actgccgtga ggcgtggcgt
    27121 aaatgtcagg cctggttgaa agatattgaa agcgctcggt tgcagcataa ccaggcgtat
    27181 accgaagcca tgcttaccga gtatgcggat tttttccgcc aggtcgagtc ttcaccgctg
    27241 aatccggcgc aggcccgggc agtcgttaat ggcgagcatt ctctgttagt gctggcaggt
    27301 gcaggaagcg gaaaaacgtc ggtgctggtg gcccgtgcag gctggttgct ggcgcgtggt
    27361 gaagcgtccc ctgagcaaat tttattgctg gcgtttggtc gcaaagccgc tgaagagatg
    27421 gacgagcgga ttcgcgaacg gctacatacc gaagacatta ccgcacgtac gtttcatgcg
    27481 ctggcgctgc atattattca gcagggcagc aaaaaagttc cgatagtcag caaactggaa
    27541 aatgataccg ctgcccgtca tgaactcttt attgctgagt ggcgcaagca atgcagcgaa
    27601 aagaaagcgc aggcgaaggg ctggcggcaa tggctgacgg aagaaatgca gtggtcagtg
    27661 ccagaaggta acttctggga tgatgaaaaa ttacagcgtc gccttgcctc tcgcctcgat
    27721 cgctgggtaa gtctgatgcg gatgcacggt ggtgcacagg cagaaatgat tgccagtgca
    27781 cccgaagaga ttcgcgatct gttcagtaaa cgtatcaagt tgatggcccc gttattaaaa
    27841 gcctggaaag gtgcgctgaa ggcagaaaac gctgtcgatt tttcgggcct tattcatcag
    27901 gcgattgtga ttctggagaa aggtcgcttt atcagcccgt ggaagcatat tctggttgat
    27961 gaatttcagg atatctcgcc gcagcgggca gcgttgttag cggcattacg caagcaaaac
    28021 agtcagacga cgttgttcgc tgttggtgat gactggcagg cgatttaccg attcagcggt
    28081 gcgcaaatgt cgctcaccac cgctttccat gaaaactttg gtgaaggcga acgctgtgat
    28141 ttagacacga cttaccgttt taacagtcgt atcggtgagg tggcaaaccg gtttattcag
    28201 cagaacccag gccagctgaa aaagccgcta aacagcttaa ccaatggaga caaaaaagcc
    28261 gtcacgttat tggatgagag tcaacttgac gctttgctgg ataagctctc tggttatgcc
    28321 aaaccggaag agcgcattct gatcctggcg cgttaccatc acatgaggcc tgccagcctg
    28381 gaaaaagcgg caacacgctg gccgaagttg caaatcgact ttatgaccat tcatgccagc
    28441 aaagggcaac aggcggatta cgtcatcatc gttggcttgc aggagggaag tgatggtttt
    28501 ccggctgcgg cgcgggagtc gattatggaa gaggcgctac tgccaccggt tgaggatttc
    28561 ccggacgctg aagaacggcg gttaatgtac gtggcgctga cccgggcacg ccatcgggta
    28621 tgggcactgt ttaacaaaga gaatccctct ccctttgtgg aaatactgaa aaatctggat
    28681 gtgccggtgg cgagaaaacc gtaagaaaca ggtggcgttt gccacctgtg caatattact
    28741 tcagacggtc cgcgagataa cgctgataat cggggatcag aatatcgacc gcgtcgttga
    28801 aatgcggcga ctggattatg aagtctgccg ttgccacgtt ggtggcgacc ggaatgttcc
    28861 ataccgtcgc cagacgcagc aaggctttca cgtcaggatc gtgcggcacg gcatttagtg
    28921 gatcccagaa gaaaatcaat acatcaattt tcccttctga gatcaatgcg ccaacctgct
    28981 ggtcaccccc cattgggcca ctcaacatcg cgttgacgtt catgccggtc gcgcgggaaa
    29041 ttaagttacc ggtagtgcct gttgcataca gtacgtgttg ttccagtaac ggttgatgcc
    29101 gttccaccca gctcatcagc atttgtttgc agtgatcgtg tgccaccagc gcaatatgtt
    29161 tccgcgcagg taaagtgcga gtcgtcagtt ccataatgta catccgtagt taactttcct
    29221 acagattact gtaagcactt atcgctgcaa gataaagacc gaaaaagcct gcgcacaggc
    29281 acaaaaatct caggaagatg gttgtttttc cgcccactgc aggaaagtat ttcgcgtttg
    29341 tgggtcagcc agtttaaacc aatacttcag ccgttgttct gtgagcacct gagactgcgg
    29401 tggaatagca tccagctcgg aaacacccga aagcagcgta ctgtcatctg ccatcatcgt
    29461 ggcaaattgc ggtagtgaag cgcgtttcgc ggatttgtta tagcgttcaa cctcgacctc
    29521 ataatcaatc gtttttgccg ttgaggtaat ggcgagaata tccagcttta ccggaatcgg
    29581 cgtcgcatcg ccatccaaca attcaaggcg cggcgcggca tcaaaatggt tagcttcccg
    29641 ctcattctcc aggcgaggca ggcgaaaatt gacctggttg atgagctggg tattaaaact
    29701 gaccaccagc ggtggggaga tatacagccg ttcttcacta ttggaaagat gaatcgtctt
    29761 ctcaacgcga aacactaact gatgcggtcc attatccagt tcaatgctgt ccgcaccgcg
    29821 cagcagagag ctggaaacct tcttgccgtc gagtaccaga agatcgacat cggttgaaag
    29881 ccgcagcgtg gtggcaaaaa cggataccgg caaacataat gcaatcaagg tggtcacgat
    29941 gccggttttc ataggtagct cctgtcaaaa gaccgcccga ataataatgt gtcaaaatt
//
LOCUS       DACAOP010000053        29719 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.053, whole genome shotgun sequence.
ACCESSION   DACAOP010000053 DACAOP010000000
VERSION     DACAOP010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29719
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.053"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(88..663)
                     /locus_tag="IT892_002626"
     CDS             complement(88..663)
                     /locus_tag="IT892_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP3135829.1"
                     /translation="MQREDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPD
                     KEAILYDALRYLSQQIDVWRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIA
                     ACTFYPDPGHPIHQLADQQKSAAYDFTHELLTTLEVDDPAMVAKQMELVLEGCLSRML
                     VNRSQADVDTAHRLAEDILRFARCRQGGALT"
     gene            complement(700..2397)
                     /locus_tag="IT892_002627"
     CDS             complement(700..2397)
                     /locus_tag="IT892_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HAP3135830.1"
                     /translation="MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFAFDFQQN
                     QHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTL
                     PVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAAPQPVSVPQQEQPT
                     AQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMA
                     LTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLT
                     LMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYAL
                     GMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDVWGLRLWSA
                     LGVAFFGWAFITSLQAKRGWMRIVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNF
                     TQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDPQVQKALADTVLLQA
                     NVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP"
     gene            complement(2373..2711)
                     /gene="cutA"
                     /locus_tag="IT892_002628"
     CDS             complement(2373..2711)
                     /gene="cutA"
                     /locus_tag="IT892_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HAP3135831.1"
                     /translation="MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIP
                     GATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTD
                     YLSWLNASLR"
     gene            complement(2827..4128)
                     /locus_tag="IT892_002629"
     CDS             complement(2827..4128)
                     /locus_tag="IT892_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter"
                     /protein_id="HAP3135832.1"
                     /translation="MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGN
                     IPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFA
                     GTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
                     GISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIE
                     IKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVI
                     CKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLA
                     VIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ
                     MDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML"
     gene            complement(4246..5682)
                     /gene="aspA"
                     /locus_tag="IT892_002630"
     CDS             complement(4246..5682)
                     /gene="aspA"
                     /locus_tag="IT892_002630"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313147.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HAP3135833.1"
                     /translation="MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDI
                     PEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGA
                     GTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSL
                     IKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNI
                     QRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGA
                     YVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPE
                     VVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCIN
                     GITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTE
                     AELDDIFSVQNLMHPAYKAKRYTDESEQ"
     gene            6019..6495
                     /gene="fxsA"
                     /locus_tag="IT892_002631"
     CDS             6019..6495
                     /gene="fxsA"
                     /locus_tag="IT892_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418564.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein FxsA"
                     /protein_id="HAP3135834.1"
                     /translation="MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGM
                     SLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLP
                     PVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD"
     gene            complement(6511..7767)
                     /gene="yjeH"
                     /locus_tag="IT892_002632"
     CDS             complement(6511..7767)
                     /gene="yjeH"
                     /locus_tag="IT892_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine/branched-chain amino acid
                     transporter"
                     /protein_id="HAP3135835.1"
                     /translation="MSGLKQELGLAQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWA
                     WPVLIILVFPIAIVFAILGRHYPSAGGVAHFVGMAFGSRLERVTGWLFLSVIPVGLPA
                     ALQIAAGFGQAMFGWHSWQLLLAELGTLALVWYIGTRGASSSANLQTVIAGLIVALIV
                     AIWWAGDIKPASIPFPAPGNIELTGLFAALSVMFWCFVGLEAFAHLASEFKNPERDFP
                     RALMIGLLLAGLVYWGCTVVVLHFDAYGEQMAAAASLPKIVVQLFGVGALWIACVIGY
                     LACFASLNIYIQSFARLVWSQAQHNPDHYLARLSSRHIPNNALNAVLGCCVVSTLVIH
                     ALEINLDALIIYANGIFIMIYLLCMLAGCKLLQGRYRLLAVVGGLLCVLLLAMVGWKS
                     LYALIMLAGLWLLLPKRKTPENGITT"
     gene            8043..8336
                     /locus_tag="IT892_002633"
     CDS             8043..8336
                     /locus_tag="IT892_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004391824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAP3135836.1"
                     /translation="MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVG
                     NGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA"
     gene            8380..10026
                     /gene="groL"
                     /locus_tag="IT892_002634"
     CDS             8380..10026
                     /gene="groL"
                     /locus_tag="IT892_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAP3135837.1"
                     /translation="MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSF
                     GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITE
                     GLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
                     LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESP
                     FILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
                     KAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIID
                     GVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAP
                     LRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAA
                     SVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM"
     gene            10164..10517
                     /locus_tag="IT892_002635"
     CDS             10164..10517
                     /locus_tag="IT892_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HAP3135838.1"
                     /translation="MHVKYLAGIVGAALLMAGCSSSNELSAAGQSVRIVDEQPGAECQ
                     LIGTATGKQSNWLSGQHGEEGGSMRGAANDLRNQAAAMGGNVIYGISSPSQGMLSSFV
                     PTDSQIIGQVYKCPN"
     gene            complement(10720..11589)
                     /locus_tag="IT892_002636"
     CDS             complement(10720..11589)
                     /locus_tag="IT892_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135839.1"
                     /translation="MAISIKGVNTGVIRKSNNFIALALKIKEPRNKESLFFMSVMELR
                     DLLIALESRLHQKHKLDAAARLQYEQARDKVIKKMAENIPEILVDELKNADINRRVNT
                     LELTDNQGENLTFVLTLHDGSKCELVVNELQIEMLARAIIHAINNAEMRELALRITSL
                     LDFLPLYDVDCQENGNLEYDTYSQPEWKHNLFDHYLAVLYRFKDESGKEQFSGAVVKT
                     REATPGKEIETITRRMLDFSPRLKKLAGVPCQVYVRTVAANNAQPLTQDQCLRALHHL
                     RVQSTSKTAPQAK"
     gene            complement(11984..13012)
                     /gene="epmB"
                     /locus_tag="IT892_002637"
     CDS             complement(11984..13012)
                     /gene="epmB"
                     /locus_tag="IT892_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HAP3135840.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGNPDDPLLRQVLTSQDEFVVASGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITDALVERFSHSTL
                     QILLVNHINHANEIDETFRQAMAKLRRVGVTLLNQSVLLRDVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
     gene            13054..13620
                     /gene="efp"
                     /locus_tag="IT892_002638"
     CDS             13054..13620
                     /gene="efp"
                     /locus_tag="IT892_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAP3135841.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            13672..13797
                     /gene="ecnA"
                     /locus_tag="IT892_002639"
     CDS             13672..13797
                     /gene="ecnA"
                     /locus_tag="IT892_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HAP3135842.1"
                     /translation="MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            13908..14054
                     /gene="ecnB"
                     /locus_tag="IT892_002640"
     CDS             13908..14054
                     /gene="ecnB"
                     /locus_tag="IT892_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HAP3135843.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            14236..14553
                     /locus_tag="IT892_002641"
     CDS             14236..14553
                     /locus_tag="IT892_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound-resistance protein
                     SugE"
                     /protein_id="HAP3135844.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(14550..15083)
                     /locus_tag="IT892_002642"
     CDS             complement(14550..15083)
                     /locus_tag="IT892_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HAP3135845.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDREMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(15172..16305)
                     /gene="blaEC"
                     /locus_tag="IT892_002643"
     CDS             complement(15172..16305)
                     /gene="blaEC"
                     /locus_tag="IT892_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HAP3135846.1"
                     /translation="MFKTTLCALLITASCSTFAAPQKINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPATKYWSELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWG
                     YREGKAVHVSPGALDAETYGVKSTIEDMACWVRSNMNPRDINDKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDSIINGSGNKIALAARPVKAITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVTAAWQILNALQ"
     gene            complement(16368..16727)
                     /gene="frdD"
                     /locus_tag="IT892_002644"
     CDS             complement(16368..16727)
                     /gene="frdD"
                     /locus_tag="IT892_002644"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HAP3135847.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            complement(16738..17133)
                     /gene="frdC"
                     /locus_tag="IT892_002645"
     CDS             complement(16738..17133)
                     /gene="frdC"
                     /locus_tag="IT892_002645"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HAP3135848.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            complement(17144..17878)
                     /locus_tag="IT892_002646"
     CDS             complement(17144..17878)
                     /locus_tag="IT892_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase/fumarate reductase
                     iron-sulfur subunit"
                     /protein_id="HAP3135849.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            complement(17871..19679)
                     /gene="frdA"
                     /locus_tag="IT892_002647"
     CDS             complement(17871..19679)
                     /gene="frdA"
                     /locus_tag="IT892_002647"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HAP3135850.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWA
                     KIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            20004..20981
                     /gene="epmA"
                     /locus_tag="IT892_002648"
     CDS             20004..20981
                     /gene="epmA"
                     /locus_tag="IT892_002648"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HAP3135851.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIDALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            21200..22702
                     /gene="yjeM"
                     /locus_tag="IT892_002649"
     CDS             21200..22702
                     /gene="yjeM"
                     /locus_tag="IT892_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418580.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HAP3135852.1"
                     /translation="MPHTIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAIPFYIF
                     SALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVST
                     SAKVWVPFSTFLYGSDMTQHWRIAGLEPTQVVGLLAVAWMILVTVVASKGINKIARIT
                     AVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLASPNPGYQSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGS
                     VNLGNITYVLMKSLGMTLGNALHLSPEASLSLGVWFARITGLSMFLAYTGAFFTLCYS
                     PLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTIFILLVSFGGGTASAFFNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTRMSAMIATVVVVLVVTFANV
                     FTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRVAKNPQWAVE"
     gene            22754..23068
                     /locus_tag="IT892_002650"
     CDS             22754..23068
                     /locus_tag="IT892_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135853.1"
                     /translation="MDDTSRDPAITEDEIRALQFSAGDVAEIEQTILSFVDACHTRKV
                     AMVVGSTINTLKDRDGKRWGNLPDIYCAYLIRCLVFRGELVGYGDLFRMRYSEIKRPV
                     TL"
     gene            23065..23379
                     /locus_tag="IT892_002651"
     CDS             23065..23379
                     /locus_tag="IT892_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeO family protein"
                     /protein_id="HAP3135854.1"
                     /translation="MSARMFVLCCIWFIVAFLWITITSALDKEWMIDGRGINNVCDVL
                     MYLEEDDTRDVGVIMTLPLFFPFLWFALWRKKRGWFMYATALAIFGYWLWQFFLRYQF
                     CL"
     gene            complement(23408..26731)
                     /gene="mscM"
                     /locus_tag="IT892_002652"
     CDS             complement(23408..26731)
                     /gene="mscM"
                     /locus_tag="IT892_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HAP3135855.1"
                     /translation="MRLIITFLMAWCLSWGAYAATAPDSKQITQELEQAKAAKPAQPE
                     VVEALQSALNALEERKGSLERIKQYQQVIDNYPKLSATLRAQLNNMRDEPRSVSPGMS
                     TDALNQEILQVSSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLG
                     TLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQL
                     DAYLQALRNQLNSQRQLEAERALESTELLAENSADLPKDIVAQFKINRELSAALNQQA
                     QRMDLVASQQRQAASQTLQVRQALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVQRLRYEDLLNKQPLLRQIHQADGQPLTAEQNRILEAQLRTQRELLNS
                     LLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDL
                     RRLISLDTFSQLGKASVMMLTSKETILPLFGALILVGCSIYSRRYFTRFLERSAAKVG
                     KVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVTATVPLL
                     WVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDRE
                     FSGSLGRLCFILICGALAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMIGAPLVA
                     ILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LAILQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVIDNPAPEVFL
                     VDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNG
                     KQTGRTLTSAGKGRQAGSL"
     gene            complement(26753..27721)
                     /gene="psd"
                     /locus_tag="IT892_002653"
     CDS             complement(26753..27721)
                     /gene="psd"
                     /locus_tag="IT892_002653"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313166.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HAP3135856.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEED
                     KILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSV
                     TKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV"
     gene            complement(27818..28870)
                     /gene="rsgA"
                     /locus_tag="IT892_002654"
     CDS             complement(27818..28870)
                     /gene="rsgA"
                     /locus_tag="IT892_002654"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313167.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HAP3135857.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIV
                     ISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLN
                     KIDLLDDEGMAFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            28965..29510
                     /gene="orn"
                     /locus_tag="IT892_002655"
     CDS             28965..29510
                     /gene="orn"
                     /locus_tag="IT892_002655"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418586.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HAP3135858.1"
                     /translation="MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGP
                     TIAVHQSDEQLALMDDWNVRTHTSSGLVERVKASTMGDREAELATLEFLKQWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
BASE COUNT         7128 a         7506 c         7765 g         7320 t
ORIGIN      
        1 taatctgcac atctcgtcaa cctaatttca gtaaaagcga ttcaactgct taagattgcg
       61 gcaaatcgct tcttttctgt gtttctgtca ggtcaatgca ccaccctggc ggcagcgggc
      121 gaagcgcagg atatcttccg ccagccgatg tgcagtgtcg acatccgcct ggctacgatt
      181 caccagcatt cggcttaaac agccttccag caccagttcc atctgctttg ctaccatcgc
      241 cggatcgtca acttccagtg tggttaacag ttcgtgggtg aaatcgtagg ccgcgctttt
      301 ttgctgatcg gccagttgat gaatagggtg gccaggatcg ggataaaacg tacaggcagc
      361 gataaataga cagcccggat agcggttgtt tttaacgcac tccgataacg cctgataacg
      421 tgccagcagc ttttgttcgg cggtttgcgt ttcgtccagc atcagctgac gacgccagac
      481 atctatctgt tggctaagat aacgcagcgc atcgtagagg attgcctctt tgtctggcca
      541 gaagcggcgt agctcgtcca gtggataatc cacacgttca gcaaccatct ccagcgtggt
      601 gttggcaatc ccttgtaatt ctaataattt cagggcttct cccagtacat cttcacgttg
      661 cacgctattt tcctccgtct ttcccactgc aagtgtcgtt cacggttggc gatcgcgcaa
      721 atgtgcgctg aaggtttcag catccataaa gcccgtgacg cgtgcttgtg gatgctcctg
      781 gccttgtccg tcaaaaaaga gaattgtcgg taggccaagg acattaagat gctttaacag
      841 cgccacatct tgtgcgtcgt tggccgtgac gttggcctga agtaagaccg tgtctgctaa
      901 cgctttttgc acctgcgggt cgctgaaggt gtatttctca aactctttac aggcgacgca
      961 ccagtcggca taaagatcta acatcaccgg tttgcctttg gcttcaacga gcgcctgatt
     1021 taactcatct accgttttga tttgtgtaaa gttgagatgc gtctgagttt gcgcggtatg
     1081 cgtcgcacca aatgcccaat cctgaagtgg gcgcacgcta accaatgccg ctgccagcag
     1141 aataatttgc acaatacgca tccagccgcg tttagcctgt aggctggtga taaaggccca
     1201 gccaaagaat gcgacaccca gcgccgacca caagcgtaat ccccatacat caccaatcac
     1261 tcgctccagc aggaagaccg gcagtgcgag gatcacaaaa ccaaacgcgg ttttgacttg
     1321 ttccatccac gggccgcttt tcggcagcaa gcggttacca aagacggtaa ttagcatcag
     1381 cggcaggccc atgcccaacg catagagata aagcgtgccg ccgcccagcc acatgttccc
     1441 gctttgggcg atatacagca gaatcgcgct aagcggtgcg gtggtgcatg gtgaacagat
     1501 cagtccggca atcgccccca taacaaacac accgccaggt gagccgccct gttggcgatt
     1561 gctcatcaac gtgagacgtg tttgcagcga agaggggagt tgcagggtaa acaagccaaa
     1621 cattgacatc gccagcaagg taaagacgat ggcgaggcca atgagcacgt atgggtgctg
     1681 tagcgccgcc tggaactgta accctgcggc ggcaaccacc agacccagcg ccgtgtaggt
     1741 cagcgccatc ccctgcacat aaataaaggt cagcaacaat gctctggcag tggagagccg
     1801 ctgtttacca cccagcacga tgccagaaat cagtgggtac attggcagca cgcatggcgt
     1861 aaaggcgata ccaataccga tcaacaacgc ccagagcgcg gaaaagggca attgcgcggt
     1921 gggctgctct tgctgcggaa cagacacagg ctgtggcgct gcgttgttgg cgaccacttc
     1981 gcttaacgga acggttttgg tttctggcgg ataacagaaa ccggcatcag cacagccctg
     2041 gtaggtgaca gttaacgtcg ctcccgcact cgcctggttg atggtgacgg gaagcgtcag
     2101 ccgatcgcgg taaatctcgc ttttgccgta aaactcatct tcatgccaga cgccttgcgg
     2161 cagctgcacg tcggcaattt tcgcgtgttc cggcgtaatg cggatctgtt tacggtagag
     2221 gtagtaaccg tctttgatct gccaggtcag attaaggtca tgttggtttt gctgaaaatc
     2281 aaaagcaaag gcttgatccg cggggacaaa ttgtgaacgt cccggcgcgt cgaataatcc
     2341 ggcaaaaacg gaagtgctgc aaagtagcag gatcagcgta aagatgcgtt gagccatgag
     2401 aggtaatctg tgtctccgtg tgtaacaggt aaaaccagaa gttccggggt ttgatatgga
     2461 tgatgagact tcaggcattc cagcagtgcc tgctggtgag atacggtagt ttttaaaatc
     2521 atctgcactt cgtattcttg ctccagctta ccttcccagt aatagagaga ggtagcgccg
     2581 gggatcaagg tcgcgcaggc cgccagtttt tccgccagca ctttggcggc taaatcctgg
     2641 gctgtcgctt catctggtgc cgtacatagc accacgacag acgcggtatt cgaacttttt
     2701 tcatcaagca taaacacctc gcaagaacag atggaaccgc aagagagagg tcactataca
     2761 acggacgggg gaaggatgtt agtcggcggg aaagaaagcg gggcgtgaac gccccgcgat
     2821 tgatcattac agcatgaagc tacccagcac gaagccgaag caaacggcca gggcaacacc
     2881 cagagtaccc gggatgaaga acggatggtt gaagacgaat ttaccgatac gggtagtacc
     2941 cgtgtcatcc atctgtaccg cagcaaccag cgtcgggtag gtcggcagaa tgaacagacc
     3001 agacaccgca gcgaaagaag caacagcggt cagcggtgaa acgttcagtg ccagagccat
     3061 cggcatcagt gcttttgcgg ttgcagcctg agagtacagc agagcagaag caaagaagaa
     3121 gatgacggcc agcagccacg gatgaccctg aatcacttca ccagcggtat ctttgatcca
     3181 gtcgatgttg ttggaaacga aagtatcgcc cagccacgca acacccagga tacaaataca
     3241 ggcgctcata cctgctttga aggtgctgga gttgaggatg ttgtcggtat cgactttaca
     3301 gataacggtg gtcagagttg caacgctgag catgatgatc aggattgcgt tggtggtgtt
     3361 catcagcggt ttttcaacca gacccatgct tgggctgttg atgattgcat agataaccac
     3421 gccaactacg cccagcagga acagccagac ggacgttttt gcaccggatt tgatttcaat
     3481 ctgcttttca ccgcgcagtt caaccaggcc ctcttccaga cgcttgcgat aaatcggatc
     3541 gtcagagagt ttggagttga acagcatagt gaccaggaag gacatcacca gaaccgccag
     3601 cagggtggac gggatgacca cggagagcag atggaggtag ctgatgccat gaccttccat
     3661 cacggaagac atgtaaacca ctgccgctga gattggcgat gcggtgatcg caatctgcgc
     3721 ggataccact gcagtagaca gcggacggca aggtttaacg ccttgttcct tcgcaacttc
     3781 agcgataact ggcagtgtcg ccagagagat gttgccagta ccagcaaaga tagtcaggaa
     3841 ataggtcacg atcggtgcga ggatcgtgat gtatttcggg ttacggcgca gcagcttttc
     3901 tgtctgatga accagatagt ccagaccgcc agcaacctgc atggcagaaa tagcggcgat
     3961 aaccgccatg ataatggaga tgacatcgaa cgggatgtta ccgggtttaa cgccaatagc
     4021 ggcaagaacc agcaccccca atccgcctgc aaaaccaata cctattcccc ccaatctggc
     4081 gcccaagaag atcgccagca aaactatgat gagttctaca actagcatat tagccttcct
     4141 tgttttttaa caagttgata ttagattgtt atttttaagt tactgctcac aagaaaaaag
     4201 gcacgtcatc tgacgtgcct tttttatttg tactaccctg tacgattact gttcgctttc
     4261 atcagtatag cgttttgctt tgtaagccgg gtgcatcaga ttctgtacgg agaaaatatc
     4321 gtcaagttcc gcttcagtca acagaccgcg ttccagaacg acttcacgta cactcttacc
     4381 ggtttcggca cagattttac ccacgatgtc accgttgtgg tgaccgatga acgggttcag
     4441 gtaagtaacg ataccgatag agttgtaaac gtaaccttcg cacacttctt tgttagcagt
     4501 gatgccgtta atgcattttt ccagcaggtt gtagcaagcg ttggtcagaa tgtgaacgga
     4561 ttcgaacatg gcctggccaa tgaccggctc cataacgttc aactgcagct gacctgcttc
     4621 tgctgccatg gtaacagtgg tgtcgttacc gatgactttg aagcatacct ggttaaccac
     4681 ttccggaaca accgggttta ctttagctgg catgatggaa gagcccgcct gcagttccgg
     4741 caggttgatc tcgttcaggc cggcacgtgg gcctgaagag agcaagcgca ggtcgttaca
     4801 gattttggac atcttcacag ccaggcgttt cagcgcgccg tgaaccataa cataagcgcc
     4861 gcagtcagag gtcgcttcga tcaggtcttc agccggtacg catgggaagc cagtaacttc
     4921 agccagtttt ttcactgcca gcggagagta ctctttcggc gtgttcagac cagtaccgat
     4981 tgctgttgca ccaaggttaa cttccagcag cagttcagcg gtacgttgga tgtttttcac
     5041 ttcttctttc agcaggatgc tgaaagcgcg gaattcctga ccgagggtca tcggtactgc
     5101 gtcctgcagc tgggtacgac ccattttcag gatgtcctgg aattcgacag ctttacgttc
     5161 aaagccttca cgcagttggt taatcgcatc taccagctta atcagggaag agtaaactgc
     5221 gatacggaaa ccggtcgggt aggcgtcgtt agtggactga catttgttaa catggtcgtt
     5281 cgggttcagg tactgatatt cacctttttg gtgacccatc agttccagac cgatattggc
     5341 cagcacttcg ttggtgttca tgtttacgga agtacctgcg ccgccctggt agacgtctac
     5401 cgggaactga tccatgcatt ttccgttgtt caggacttca tcacatgcgg caatgatggc
     5461 attcgctaca cttttaggaa tggtttgcag ctctttgttt gccatagctg cggctttttt
     5521 aaccattacc ataccgcgaa caaattcagg aatatcactg attttgttgt tgctgatata
     5581 gaagttttca atcgctctca gagtgtgaac accatagtag gcatcagctg gaacttccct
     5641 ggtacccaac agatcttctt cgatacgaat gttgtttgac atgtgaacct tctttttcaa
     5701 gctgccaatg atttgcttta aacacacaga atatatgtgg tttcgaatgt ttttcgaccg
     5761 acgattatcc cctgcatcga ccgaataccc gagatcatat gctgcttgag gatttctacc
     5821 gtaatctgga tcactttaag tgtcggtttt taccccttaa ttattaattt gtgaaataga
     5881 tcaccgcttt gggattacta ccaaaaatag ttgcgcaaac atcttgaaat tttgctaatg
     5941 accacaatat aagctgaacg cgattcgcaa cccattcagg tagccgggtt ttaccggctg
     6001 ctattacagg agaaaccttt gcgctggtta ccttttattg ccattttcct ttatgtctat
     6061 attgagattt caatctttat tcaggttgcc catgtattgg gggtattgct gaccctcgtg
     6121 ctggttatat tcacgtcagt tatcgggatg tcactggtac gtaaccaggg ctttaagaat
     6181 ttcgtgctga tgcagcaaaa aatggcggcg ggtgaaaacc cagcggcgga gatgattaaa
     6241 agtgtttcgc tgatcattgc cggtttgctg cttttattac cgggcttttt caccgacttc
     6301 ctcggtcttc tgcttttatt accgccggtg caaaagcatc tgacagtgaa gttgatgccg
     6361 catttgcgct tttctcgtat gccaggcggc ggttttagcg ccgggaccgg tggcggtaat
     6421 acttttgatg gtgagtacca gcgaaaggat gatgagcgcg accgccttga tcataaagac
     6481 gatcgccagg attaatgtcg aaacgccgga ttatgtggtt atgccatttt ccggcgtttt
     6541 tcgttttggc agcaacagcc ataaccccgc cagcatgatc agcgcataga gacttttcca
     6601 gccgaccatt gccagtaaca gaacgcataa cagcccgcca accaccgcca gtagtcgata
     6661 acgtccttgc aataatttac agcctgccag catgcataac agataaatca taataaagat
     6721 gccattggca taaataataa gagcgtccag attgatctct aaagcatgaa tcaccaaagt
     6781 gctcaccacg cagcagccga gcaccgcatt gagggcatta ttcgggatat ggcgagaaga
     6841 gaggcgtgcc aggtagtggt caggattatg ttgcgcctgc gaccagacca ggcgggcgaa
     6901 gctctgtata taaatgttga gactggcaaa gcaggccaga tagccaatta cgcaggcaat
     6961 ccataacgct cctacaccga acagttgcac tacaattttt ggaagcgatg ctgccgcggc
     7021 catttgttca ccataggcgt cgaagtgtaa gacgactacc gtacagcccc agtagactaa
     7081 tcctgccagc agcagaccaa tcatcaaagc acgaggaaaa tcacgttctg gatttttaaa
     7141 ttccgaggca agatgggcaa atgcttccag accgacaaaa caccagaaca tcactgataa
     7201 cgcagcaaat aacccggtaa gttcgatatt tcctggcgcg gggaagggga tactcgcagg
     7261 tttgatatcg cccgcccacc agatagcgac aatcagtgcg acgataagtc cggcaataac
     7321 ggtttgtaga tttgcactgg aactggcacc gcgagtaccg atataccaca ccaacgccag
     7381 cgtaccgagt tctgccaaca acagttgcca gctatgccag ccaaacatcg cctggccgaa
     7441 cccggcggca atttgtagcg cggcaggcaa acccacggga atgaccgata aaaacagcca
     7501 gccggtgact cgctcaagcc gcgaaccaaa cgccataccg acgaagtgcg cgacgccgcc
     7561 tgcactggga tagtggcgac ccagaatcgc aaacacaatc gcaatcggga acactaagat
     7621 aatcaaaacg ggccacgccc acaggctgtt attgcccgct accagcgcag ctaacgcagg
     7681 aacggcaaac acgccagtgc ctaataatga cgtcgatagc agtccaatgc cctgggccag
     7741 ccccagttct tgtttgagtc cactcatggg ttgatatccg attgcgccca aattttgggc
     7801 aactgcgtag attttcgatg gtagcacaat cagattcgct tatgacggcg atgaagaaat
     7861 tgcgatgaaa tgtgaggtga atcagggttt tcacccgatt ttgtgctgat cagaattttt
     7921 tttctttttc ccccttgaag gggcgaatcc tcatccccat ttctctggtc accagccggg
     7981 aaaccacgta agctccggcg tcacccataa cagatacgga ctttctcaaa ggagagttat
     8041 caatgaatat tcgtccattg catgatcgcg tgatcgtcaa gcgtaaagaa gttgaaacta
     8101 aatctgctgg cggcatcgtt ctgaccggct ctgcagcggc taaatccacc cgcggcgaag
     8161 tgctggctgt cggcaatggc cgtatccttg aaaatggcga agtgaagccg ctggatgtga
     8221 aagttggcga catcgttatt ttcaacgatg gctacggtgt gaaatctgag aagatcgaca
     8281 atgaagaagt gttgatcatg tccgaaagcg acattctggc aattgttgaa gcgtaatcct
     8341 cgcacgacac tgaacatacg aatttaagga ataaagataa tggcagctaa agacgtaaaa
     8401 ttcggtaacg acgctcgtgt gaaaatgctg cgcggcgtaa acgtactggc agatgcagtg
     8461 aaagttaccc tcggtccgaa aggccgtaac gtagttctgg ataaatcttt cggtgcaccg
     8521 accatcacca aagatggtgt ttccgttgct cgtgaaatcg aactggaaga caagttcgaa
     8581 aacatgggtg cgcagatggt gaaagaagtt gcctctaaag cgaacgacgc tgcaggcgac
     8641 ggtaccacca ctgcaactgt actggctcag gctatcatca ctgagggtct gaaagctgtt
     8701 gctgcgggca tgaacccgat ggacctgaaa cgtggtatcg acaaagccgt taccgctgca
     8761 gttgaagaac tgaaagcgct gtccgtaccg tgctctgact ctaaagcgat tgctcaggtt
     8821 ggtaccatct ccgctaactc cgacgaaacc gtaggtaaac tgatcgctga agcgatggac
     8881 aaagtcggta aagaaggcgt tatcaccgtt gaagacggta ccggtctgca ggacgaactg
     8941 gacgtggttg aaggtatgca gttcgaccgt ggctacctgt ctccttactt catcaacaag
     9001 ccggaaactg gcgcagtaga actggaaagc ccgttcatcc tgctggctga caagaaaatc
     9061 tctaacatcc gcgaaatgct gccggttctg gaagctgttg ccaaagcagg caaaccgctg
     9121 ctgatcatcg ctgaagatgt tgaaggcgaa gcgctggcaa ctctggttgt taacaccatg
     9181 cgtggcatcg tgaaagttgc tgcggttaaa gctccgggct tcggcgatcg tcgtaaagct
     9241 atgctgcagg atatcgcaac cctgactggc ggtaccgtaa tctctgaaga gatcggtatg
     9301 gagctggaaa aagcaaccct ggaagacctg ggtcaggcta aacgtgttgt gatcaacaaa
     9361 gacaccacca ctatcatcga tggcgtgggt gaagaagctg caatccaggg ccgtgttgct
     9421 cagatccgtc agcagattga agaagcaact tctgactacg accgtgaaaa actgcaggaa
     9481 cgcgtagcga aactggcagg cggcgttgca gttatcaaag taggtgctgc taccgaagtt
     9541 gaaatgaaag agaaaaaagc acgcgttgaa gacgccctgc acgcgacccg tgctgcggta
     9601 gaagaaggcg tggttgctgg tggtggtgtt gcgctgatcc gcgtagcgtc taaactggct
     9661 gacctgcgtg gtcagaacga agaccagaac gtgggtatca aagttgcact gcgtgcaatg
     9721 gaagctccgc tgcgtcagat cgtcctgaac tgcggcgaag aaccgtctgt tgttgctaac
     9781 accgttaaag gcggcgacgg caactacggt tacaacgcag caaccgaaga atacggcaac
     9841 atgatcgaca tgggtatcct ggacccaacc aaagtaaccc gttctgctct gcagtacgcg
     9901 gcttctgtgg ctggcctgat gatcaccacc gagtgcatgg ttaccgacct gccgaaaaat
     9961 gatgcagctg acttaggcgc tgctggcggt atgggcggca tgggtggcat gggcggcatg
    10021 atgtaattgc cctgcacctc gcagaaataa acaaaccccc gggcagaaat gtctgggggt
    10081 ttttcttttg gtcatctttc tagtataaga ttcagacacg gacgacgcga gtggcgtcca
    10141 gctcattgat tatggggaat aacatgcacg taaaatactt agcagggatt gtcggtgccg
    10201 cgctactgat ggcgggttgt agctccagca acgaattgag tgctgccggt cagagtgtac
    10261 gcattgtgga cgagcagcca ggcgcagagt gccagctgat tggtactgcg acaggtaagc
    10321 aaagcaactg gctttccggg caacacggag aagagggcgg ttctatgcgc ggcgcagcaa
    10381 acgatctgcg caaccaggcg gctgcaatgg gcggtaacgt gatttatggc atcagcagcc
    10441 cgtcgcaggg aatgttgtcc agttttgtcc cgacggatag ccagattatc ggtcaggttt
    10501 ataagtgccc gaactgatgt gatccagagg ctgggtgaca aacgtattat tgcctgatgc
    10561 gcttcgctta tcaggcctac agcaggcatt gcaactgatt gaatgcttga gaatttgtag
    10621 gccggataag gcgtttacgc cgcatccggc atgaccaacg atcacgttat cagtcatttc
    10681 aggctggatg gctccagcct cgcattagca aagatgagat tatttcgcct gtggtgcagt
    10741 tttgctggtg gattgaacac gtaagtgatg cagcgcgcgt aagcattgat cctgggttag
    10801 cggttgggcg ttattcgccg ctacggtgcg aacatagacc tgacatggca cacccgcgag
    10861 ttttttcagt cgtgggctga aatcaagcat tcggcgagtg atcgtctcta tttctttacc
    10921 cggcgttgct tcacgcgttt tcaccactgc gccgctaaat tgttctttgc cactttcatc
    10981 tttaaagcgg taaagcaccg ccagataatg gtcgaacagg ttatgtttcc attccggttg
    11041 ggaataggtg tcatattcca gattgccatt ttcttggcag tcaacgtcat ataacggcag
    11101 gaaatctaac agtgaggtaa tacgtaatgc cagttcacgc atttccgcat tattaattgc
    11161 atgaatgatt gctcgcgcca gcatttcaat ctgcaactca ttgacgacta actcacattt
    11221 gctaccgtca tgtagcgtta atacgaaggt aagattttcg ccttgattat cggtaagttc
    11281 cagcgtgtta acccgacgat taatatcggc atttttaagc tcatcaacca gaatttctgg
    11341 gatgttttct gccattttct taatgacttt atcgcgagct tgctcatact gaaggcgtgc
    11401 agcagcatcc agtttatgct tttgatgcag acgactttcc agcgcaatca gcaggtcgcg
    11461 cagttccatg acagacataa agaacaacga ttctttattg cgaggttctt taattttcag
    11521 cgccagtgca atgaaattat tactcttgcg aataacaccg gtattaacac ccttgatgct
    11581 tatggccatg taggttctcc ctaaccattt ctcaattaaa taattaattt taatttataa
    11641 gccagataaa tgggcttggt agtaatagtt gttaaaataa cataaatagc cgtgctcact
    11701 ctatataaac agaaaagaaa ggttaattat tggtgttagc tatataaaaa gtaacaacag
    11761 caatgcatat gaataattaa aggttatgca acgtgcaaag attaaatttc tcagtttaat
    11821 gacaggttgc tgtacttgcg tttgttgctc ttgccggatg cggcgtaaac gccttatccg
    11881 gcctacagtt cattgcaaat ccattcaatt tcaatgcacg atgtaggcct gataagcgta
    11941 gcgcatcagg caattttaat gtttaacttc cctgtttaat cagttactgc tggcgtagct
    12001 ggagatccag cggcgttttg ctgggttcgc cgccaatttc tcgcgccagt ttcggcacca
    12061 gatatcccga caccaatgtc agcaactcac gcataatctg ccgtgcttcg tcatcactca
    12121 ccataaaatg cgccgcgccc tgtactttat cgagcacatg caggtaatac ggcatcacgc
    12181 cggcatcgaa caacgcatta ctcaggtttg ccagcgtttg tgcgttatcg ttcacatcac
    12241 gtaacagaac gctctggttc agcaaagtaa cgcctacccg gcgcaactta gccatcgcct
    12301 gacggaatgt ttcatctatc tcattggcat ggttgatgtg attcaccagc aagatttgca
    12361 gcgtagaatg tgaaaagcgt tcaaccagcg catctgtgat gcgtgccggg atcacaatcg
    12421 gcagacggct gtgaatccgc agacgtttga tatgcgggat ggcttccagt tgtgtgagca
    12481 accagtccag ctcgtgatct ttcgccatca gcggatcgcc gccagagaaa atcatctcgt
    12541 ccagttccgg atgcgcagca acatactcaa gtgcagtctg ccagttacgc ttgttgccct
    12601 gattttcggc ataggggaag tggcgacgga agcaatagcg gcaatttacc gcgcagccgc
    12661 ctttgaccag caaaagcgcc cggttgtggt atttatgcaa caaaccaggc actacgctgt
    12721 gctgttcttc cagtgggtcg gtggagaatc cggacgcgac gacaaactca tcttgcgagg
    12781 taagtacctg acgcaaaaga ggatcgtccg gattgccttt ctccatgcga tcgataaatg
    12841 agcggggcac acgcagggca aacagctttt tggcgctgcg tccggccaac agtttttcgt
    12901 ccgcgtctat attcaaaaga cgcagaagtt catcaggatc ggtcacaaca tcggcaagtt
    12961 gcgttaacca atcttctctg gatggggtat ttagggttac aatatgcgcc attttgtggc
    13021 ttagctacca attaacaaat ttcagagggc cttatggcaa cgtactatag caacgatttt
    13081 cgtgctggtc ttaaaatcat gttagacggc gaaccttacg cggttgaagc gagtgaattc
    13141 gtaaaaccgg gtaaaggcca ggcatttgct cgcgttaaac tgcgtcgtct gctgaccggt
    13201 actcgcgtag aaaaaacctt caaatctact gattccgctg aaggcgctga tgttgtcgat
    13261 atgaacctga cttacctgta caacgacggt gagttctggc acttcatgaa caacgaaact
    13321 ttcgagcagc tgtctgctga tgcaaaagca attggcgata acgctaaatg gctgctggat
    13381 caggcagagt gtatcgtaac tctgtggaat ggtcagccga tctccgttac tccgccgaac
    13441 ttcgttgaac tggaaatcgt tgataccgat ccgggcctga aaggtgatac cgcaggtact
    13501 ggcggcaaac cggctaccct gtctactggc gctgtggtta aggttccgct gttcgtacaa
    13561 atcggcgaag tcatcaaagt ggatacccgc tctggtgaat acgtctctcg cgtgaagtaa
    13621 tgcggttgtg gtgcggcctg caggctgcac catcacttat tcaggtcaga gatgatgaaa
    13681 cgccttatcg ttcttgtttt gcttgccagc acgctgctca cgggctgtaa caccgctcgc
    13741 ggtttcggcg aagacatcaa acatctcggc aactccatct ctcgcgctgc cagctaattt
    13801 ttcttctctt ccgaaaaatc atcagatttc cgtcattttt ggcgatgttg tctattatta
    13861 atttgctata ggcaaacata aataacatta cctaaaagga agacgttatg gtgaagaaga
    13921 caattgcagc gatcttttct gttctggtgc tttcaacagt attaactgcc tgcaacacca
    13981 cgcgtggcgt tggtgaagac atttctgatg gcggtaacgc gatttctggc gcagcaacga
    14041 aagcgcagca atagcaataa gcaataacgg tacgacagct gtgtcgtgcc gtttgttttt
    14101 tctgcgatag tcactaaggt aatagttgaa attcccctgc cacctggcaa aatatccgtt
    14161 caaccatcag ctttgcagga cgacctgcaa acgcgtcttt tcaccgggga cggccccaat
    14221 tctccggagc ctgatatgtc ctggattatc ttagttattg ctggtctgct ggaagtggta
    14281 tgggccgttg gcctgaaata tacccacggc tttagtcgtt tgacgccgag tgttattacc
    14341 gtgacggcga tgattgtcag tatggcgcta cttgcctggg cgatgaaatc gttaccagta
    14401 gggacggctt atgccgtgtg gacgggtatt ggcgcagtcg gcgcggctat caccggcatt
    14461 gtactgctcg gtgagtccgc taacccgatg cgcctggcga gtctggcgtt aatcgtattg
    14521 gggattattg gtctgaaact cagcactcac taactaccgg gctgctgtac ccaaataaac
    14581 ttactgacat caaacccttc ccgggtcgcg actgccagca tctcctgttt cacttcgtca
    14641 gaaatggttg gcgtgcggga gagtatccac aggtagtcgc ggtccgggcc gcaaaccagc
    14701 gcatggcggt attcccgatc aagtgcaatg acgttataac cgccatagaa aggaccaaag
    14761 aatgacactt tcagcgcagc gcgtgttggt gcgccggtaa agtacgcttt cccttcactc
    14821 tgctgccaca tttctctgtc agggttatag cctttattga tgacattcag gccgccgtca
    14881 tcacgcagac tgtatgttgc ggtgactttt tccagtccac gttcaaaacg gtgatcaaaa
    14941 cgggcaatct cataccaggt accgagatag cgtttagcgt cgaaattatt cactactgtc
    15001 acgccacgcg gcggcgtagg agaactgcag gcaacgacca gaaatgcagc tgtcgctgcg
    15061 gcaacgagag ggagcaggcg cataaatgtt tccttactgg tttttttcta agtgtagatg
    15121 acagcaagga aaagcgcaga aaaggtccga aaattcggac ccgatgaaat tttactgtag
    15181 agcgttgaga atctgccagg cggcggtgac tctcgctgga ttgggatagt ttttgttagc
    15241 cagcatcact atacccagct ctttttctgg aataaacgcg acatagctac caaatccgcc
    15301 ggttgcccct gttttatgta cccatgatgc gcgtactgca ggagttgggg gcgtaatcgc
    15361 ttttacgggg cgtgctgcca gtgcaatttt attgccactg ccgttaatga tgctgtcagg
    15421 atttaccggc cagtccagca tttcccagcc caggccctga tacatatcgc cggtttgcca
    15481 gtagcgagat tgtgccagtt gtatcccttg ctgaagtgtt ttgtcgttga tatcacgggg
    15541 attcatattg cttcgtaccc agcaggccat atcttcaatg gtcgacttca caccataagt
    15601 ttcagcatct aacgcccctg gcgaaacatg aactgccttg ccttcgcgat atccccaggc
    15661 gtaattcttt tcttctgcgg gcggtacatt aatccacgta tggttgagtt tgagtggctg
    15721 gaagacacgt gtttgcatcg cctgctcaaa actcaaacca gacggcttca cagccagtgc
    15781 gccgaacaaa ccgatactgg agttggcata cagacgttgt gttcctggag cccatgcagg
    15841 ctgccagttt tgatagaagc gcagcaagtc gcttgaggat ttcacctcat ccggcacctg
    15901 caatggcagg ccgccagcgg tgtaggttgc gagatgtaat agtgtgatcc cgttccactg
    15961 tttagcggta agttcagacc agtattttgt tgcgggatcg cttaacttga tttcccctcg
    16021 agcaatagcg tcgccaccaa gcacgcccgt aaatgttttg ctgaccgaac ctaactcaaa
    16081 caacgtttgc tgtgtgacgg gctgtttttt ggcgatgtcc gcatagcccc aggtaaagta
    16141 ataaggttta ccctgataaa ttaccgccac cgccataccg gggatctttt gttgctctat
    16201 aagcggggta attgtgcgat gcacaatatc gttgattttt tggggggcag caaatgtgga
    16261 gcaagaggcg gtaattaata aggcgcagag cgtcgttttg aacatagggt ctggtttcca
    16321 tacaaaacgg cccgccatag gcgggccgga tttacattgg cgatgcgtta gattgtaacg
    16381 acaccaatca gcgtgacaac tgtcaggata gcagccagac cgtagaaaac ccatttgccc
    16441 gcaggtacgt ggattttcag atcgtgcatc gcgtggtgca tacggtgtaa accacaccac
    16501 agcggcagaa cgatcatcag gaacaggaat acgcgaccaa tgaagctctg cgcgaacgcc
    16561 agaacgcgct cgtagctcag tgcatcaccc ggaaacagcc ccagcggcag cagaataccc
    16621 accagcagga tcatcaccgg cgcaataatt gcgctccaca taccaccggc cccgaagagg
    16681 ccccagaata ccggttcgtc agaacgcttt ggatttggat tgatcatctc aggctcctta
    16741 ccagtacagg gcaacaaaca ggattacgat ggtggcaacc acagttaccg cccagagact
    16801 tttgataatt ggctctggac ccattttttc gtcttttaca atgatattgg ccgctttcgg
    16861 tgccagttca aaccaggttt tggtgtgcag cagagctgcc gccagagtga tcaggttaat
    16921 gatcacaata accgggtttt gtaaaaagtc gacgaatccc gcccaggctt ccgggccatt
    16981 tttcagagca aacagcccga aaatcagttc aatgctgaac cacacagccg gaaccgccgt
    17041 gccttcgcgc agcatgtaaa agcgataaaa cggcaatttt ttccaccagg tggacgtcat
    17101 tggccgtaca tacggtttac gtttagtcgt catgttgcac tccttagcgt ggtttcaggg
    17161 tcgcgataag aaagtctttc gaactttcta ctttgccctg ctgaatggcc gcagccggat
    17221 cgacgtgttt cgggcagact tcggagcaat agcccacgaa agtacagctc catacgccgt
    17281 tctggctgtt caactgcgcc atacgctcct tcttaccgtg gtcgcggcta tcttcgttat
    17341 aacgatgcgc cagcgtaatg gcagccggac cgatgaactc tgggttcagg ccaaactgcg
    17401 ggcacgcggc gtagcacaga ccacagttga tgcaaccgga gaactggtga tacttcgcca
    17461 tctgcgccgg ggtctggatg ttagtaccct gatccgcggt gcgggagttg ccgatgatgt
    17521 acggtttgat cgcttccaga ctttcgatga agtgggtcat atcgaccacc agatcgcgtt
    17581 caatcgggaa gttagctaac gcttcaacct tcataccgtc ggtgtaatca cgcaggaagg
    17641 ttttacatgc cagttttggc acgttgttaa ccatcatgcc gcaggaacca caaatcgcca
    17701 tacggcagga ccagcggtag ctcaggtccg gtgccaggtt gtctttgatg tagcccagcg
    17761 catccagtaa tgaggtagtt gcgtcataag gcacttcata gaatgcgcta tgcggtgcgg
    17821 tatcgacttc cgggttatag cgcaccacct caattttcag gtttttcatc tcagccattc
    17881 gccttctcct tcttattggc tgcttccgcc ttatcggctg catccgcttc gccaccgtaa
    17941 acgcgtttag ctggcggcag cgtagtaatc ttcacgtcgc tgtactccag gcgagtcgtg
    18001 ccatcagcat cgcggaaggc gagggtgtgt ttgaggaagt tgacgtcgtc acgctcggtg
    18061 caaccttcgt ccagacgctg gtgtgcgccg cgggactctt tacgtgccat tgcggagtgc
    18121 gccatacatt cagcaacgtt cagaccgtgg cccagttcaa tggtgtagag caggtcggtg
    18181 ttgaacacgc tggaagtgtc ggtgatgcgc acgcgcttga agcgttcctg cagctctgcc
    18241 agcttgtcga tggttttctg catcagttcc ggcgtacggt agataccgca accttcttcc
    18301 attgccaggc ccatttcgtc gcggatcttc gcccagtttt cgccgccatc ctggttaacc
    18361 agatctttca gacgttgttc aacgccagct gcctgcgctt caattgccgc ttcgttgcca
    18421 ttaccggcag ttgctgcacg ctctgtcgct tgttcaccgg ccagacggcc gaagaccacc
    18481 agttccgcca gggagttgga gcccagacgg tttgcaccgt gcagaccaac agaggaacat
    18541 tcacccacgg cgaacagacc tttaatgcgg gtttcacagt tctgatcggt ttcgataccg
    18601 cccatggtgt agtgtgcggt cggacgtacc ggaatcggtt ctttaaccgg atcgacgcca
    18661 acgtacgctt tcgccagttc gcagatgaac ggcagacgtt catgcagttt tttctcgccg
    18721 aggtgacgca ggtcgagata aaccacatca ccacgcggcg tggagatggt gttgccttta
    18781 cgccattcgt gccagaaggc ctgagaaact ttgtcgcgtg gacccagttc catatatttg
    18841 tttttcggct cgcccagcgg agtttccggg cccatgccgt aatcttgcag ataacggtag
    18901 ccatttttgt tgaccagaat accgccttca ccacggcagc cttcggtcat caggataccg
    18961 gaacctggca gaccggttgg gtgatactga acgaattcca tgtcacgcag cggaacgccg
    19021 tggcttagcg ccatacccat accgtcaccg gtaacgatgc cgccgttggt gttgtaacga
    19081 taaacgcgac ccgcaccgcc ggtagccata acgaccgcgt tagcacggat ctgcaccagc
    19141 gtgccttcca tcatgttcat tgctaccagg ccgcgaacat gaccatcatc aaccagaata
    19201 tccagcacga aatgttcgtc aaaacgctgg atctgcggga attgcagaga ggtctggaac
    19261 agcgtgtgca gcatatggaa gccggtctta tcggcggcga accaggtacg ctcgattttc
    19321 atgccgccga agcgacgtac gttgacgcta ccatccgggc gacggctcca tgggcacccc
    19381 cacagttcca gttgggtcat ttcggttggg cagtggtgga cgaaataatc cacgacatcc
    19441 tgctcacaca accagtcgcc acccgctact gtatcgtgaa agtgatattc gaagctgtca
    19501 tgatcctgcg cgacagcggc ggagccccct tctgcagcaa cggtatggct acgcatcggg
    19561 tatacttttg agattagtgc gatttttgca tttggatttg cctgcgcggc agcaattgca
    19621 gcacgtaatc ccgcgccacc ggcgcctaca atggcaagat cggcttgaaa ggtttgcacg
    19681 acattcctcc agattgtttt tatcccacag ccccgtactt cagggtaagt gcctgaaagt
    19741 tacggtctgc gaacgctatt ccactgctcc tttataggta caacagtata gtctgatgga
    19801 taagtctgaa atttgacgag atcgattttt ttagtgcgca agagggctaa attatcactg
    19861 aagatgatta atttaattac taaaccatca gatcgtgctt tttttagtca ctgcccaccg
    19921 ttgtttgatt cctgcgtaaa atttgtctcg ccgtcgcgtt gcgagtagac ttcgtgccct
    19981 tgtcaaaaac tggagattta actatgagcg aaacggcatc ctggcagccg agcgcatcca
    20041 ttcctaactt attaaaacgc gcggcgatta tggcggagat ccgtcgtttc tttgccgatc
    20101 gtggagtgct ggaggtggag acgccttgta tgagccaggc gacggtaacc gatattcatt
    20161 tggtcccgtt tgagacacgt ttcgttggcc ccgggcattc gcaggggatg aatctctggt
    20221 taatgaccag cccggaatac catatgaaac gcctgctggt tgccggttgt gggccggtat
    20281 tccagctgtg ccgcagtttc cgtaatgaag agatggggcg ttatcacaac cctgagttca
    20341 ctatgctgga gtggtatcga ccgcactatg atatgtaccg gttgatgaac gaggtggacg
    20401 atctcttaca acaggtgctg gactgccctg cagcagaaag cctttcttat caacaagctt
    20461 tcttgcgtta tctggaaatt gacccactct ctgccgacaa aacgcaactg cgggaagtgg
    20521 cagcgaaact ggatttgagc aatgttgctg ataccgaaga agaccgcgac acgttgctac
    20581 aattgctgtt tacctttggc gtagagccaa atattggtaa agaaaaaccg acctttgtgt
    20641 accactttcc agccagccag gcatcactgg cgcaaatcag taccgaagat catcgggtcg
    20701 ctgaacgctt tgaggtttat tataaaggta ttgagctggc gaatggtttc catgaattga
    20761 cggatgcccg tgagcagcaa caacgctttg aacaagataa ccgtaagcgc gcggcgcgcg
    20821 gtttgccgca gcaccccatt gaccagaatc tgattgacgc cttgaaagtc ggtatgcctg
    20881 actgttccgg cgtggcatta ggtgttgatc gtctggtgat gttggcgctg ggcgcggaga
    20941 cactggctga agtcatcgcc tttagcgttg accgggcata attctgaaaa attactgaat
    21001 taacagcgaa gaatggcgta ataagcgcca ttctgtagca tatattttca tttttccgct
    21061 aaaggccaca atttaagact ggatatttga tatcatccag gtatcaattc tgtattggtt
    21121 tttacgctgc ctgctcaatg ttgcgcagtg cagttcagtg ggcacgtgtt atacacgcgc
    21181 tgaaatgaag gatggtttca tgcctcacac gataaaaaaa atgagtctga taggactcat
    21241 attgatgatc tttacttccg tatttggttt tgccaatagc ccatcggctt attacttaat
    21301 gggttatagt gcgattccct tttatatatt ttctgcattg ttattcttta ttccattcgc
    21361 cttaatgatg gctgaaatgg gagctgctta tcgcaaagaa gaaggtggta tctattcctg
    21421 gatgaataat agtgtcggac cacgttttgc cttcattggt acgtttatgt ggttttcctc
    21481 ttatatcatc tggatggtga gtacctccgc gaaagtttgg gtaccgttct caacattcct
    21541 ctatggtagc gacatgaccc agcactggcg tattgccgga ctggagccta cgcaggtggt
    21601 tggtctgctg gcagtggcat ggatgattct ggtcaccgtc gttgcttcta aggggattaa
    21661 taaaattgcc cgcattactg cggtgggcgg tattgcagta atgtgtctga atttagtatt
    21721 gctgttagta agcattacta ttttgttatt aaatggtggg catttcgcgc aggatattaa
    21781 tttccttgca tcaccgaacc cgggttatca gtccggtctg gcaatgctat cgtttgtggt
    21841 atttgccatt tttgcctatg gcggaattga agcggttggt ggtctggtcg ataaaacgga
    21901 aaatccagaa aagaactttg ccaaaggtat tgtttttgcc gctattgtta tttcaatcgg
    21961 ttattcgctg gcaatatttt tatggggcgt cagcacaaac tggcagcagg tattaagtaa
    22021 tggttccgtt aacctcggca atattaccta tgtgctgatg aagagccttg ggatgacgct
    22081 gggtaatgca ctgcatttgt cacctgaagc gtcattgtcg ctgggcgtat ggtttgcgcg
    22141 tattactgga ctttcgatgt tcctcgccta taccggtgcg ttctttacgc tttgctattc
    22201 accgttgaaa gccatcatcc aggggacgcc gaaagcattg tggccggaac cgatgacgcg
    22261 tctgaatgcg atggggatgc cgtctatcgc catgtggatg cagtgcgggt tggttactat
    22321 cttcattctg ctggtttcgt ttggtggcgg taccgcatcg gcgttcttta acaagctgac
    22381 gctgatggcg aacgtgtcta tgacgcttcc ttacctgttc ctcgcgctgg ctttcccatt
    22441 ctttaaagca cgtcaggatc tcgacagacc atttgtgatt ttcaaaacgc gtatgtcggc
    22501 aatgatcgcg acggtggttg tcgtactggt ggtgacattt gcgaacgtct tcaccatcat
    22561 tcaacctgtg gttgaagctg gagactggga cagcacattg tggatgattg gcggccctgt
    22621 cttcttctcg ctgttagcga tggcgattta ccagaactat tgcagcagag tggcaaaaaa
    22681 tccgcagtgg gcggtggaat aacccgatgc cctatcgtct acctgacgat agggcgtaaa
    22741 gacaggaaat gttatggatg acaccagccg ggacccggca ataaccgaag atgaaatcag
    22801 ggcgctgcaa ttttctgccg gggatgtagc ggaaatagag cagacgattc tctcttttgt
    22861 cgatgcctgc cacacccgta aagtggcgat ggtggtgggt agcaccatta acaccctcaa
    22921 agatcgcgat ggtaaacggt ggggaaacct gccggatatt tattgcgctt atcttatccg
    22981 atgtctggtt tttcgcgggg aattagtggg atacggcgat ttgtttcgta tgcgctatag
    23041 cgaaattaag cgaccggtta ccttatgagt gcgcgcatgt ttgtcttatg ctgcatctgg
    23101 tttattgtgg cgttcctctg gataaccatc acttccgcgc tggacaaaga gtggatgatt
    23161 gatggacgcg ggattaacaa cgtctgcgat gtgttgatgt atctcgaaga agacgatacc
    23221 cgtgatgttg gtgtgataat gacgttaccg ctctttttcc cttttctctg gttcgctttg
    23281 tggcgaaaaa aacgcggctg gtttatgtac gccaccgcgc tggctatttt cggctactgg
    23341 ctgtggcagt tttttctgcg ctatcagttt tgtttgtgag ccggattggt tcatccggca
    23401 cacaaactta caaacttccc gcctgacgac ctttgcccgc agacgtcagc gttctccccg
    23461 tttgtttacc gttgaggctt tccagacgca tctggaaggg cgggaatggc atatcgatac
    23521 cgtgggcatg gaagccagcc agaatcagct ggtggatctc atggcgtagc ggcatacggt
    23581 gacccatctc agcggcgtaa atacgcagct cgaaaatctg aatcccctgt tgcagatcca
    23641 ccaggaagac ttccggtgcc gggttgtcga tcaccagcga gcagcgacgc gctgcggtga
    23701 gcaggatttc cgtcacttct tcgctattgg catcggcagg ggccggtatc gtcaacacca
    23761 cgcgcgtgac cgagtcagag agcgaccagt tgataaactg ctcggtaata aacgccttgt
    23821 tcggcacgat tatctcttta cggtcccagt cgctgatggt ggtggcgcgg gtgttaattt
    23881 tcgtcacgct accggtgaga tcgcgaattg tcaccgtatc gccaatgcga atcggttttt
    23941 cgaacaggat aatcagacca gagataaagt tggcgaaaat ttcctgcaaa ccaaaaccga
    24001 gaccaacacc gagcgcggca accagccact gcaatttcga ccactcaata ccaatcattg
    24061 agaagccgac cagcccgcca atcagcatca gcagatattt ggtgatggtg gtgatggcgt
    24121 aacccgtacc cggcgttaaa tccaggtgct gcaaaatcgc cagttccagc agcgcgggta
    24181 ggttgcgcac cagctgcgtg gtgatgataa ataccagaat ggcaattagc actgcaccga
    24241 gggtaatcgg ctccaggctt tctacgccct gtacagtgga agtgacatcc cacagagaaa
    24301 tattttcgag gaagccgaaa gcggaatgga tttctgacca cagcacaatg accgaaagca
    24361 gggcgatcaa catcaaaatt gagcgcacca gccgcaagga ttgcgcactg atggcatcga
    24421 gatcgacttc gctttcatcg acttcaattg ccccttccgg gctactgtga tgatgcgctt
    24481 cctcttcgcc acgcgcgcgt tgcgctaaca tctctgcccg gcgatgcttc gcccggtcaa
    24541 acgccagcct gcgacgctgg atcagcatcc agcggcggat aacgtgataa accaccagta
    24601 gcaggaacca gatggcaacc gaggtttcaa gcctcgctaa cagcgcctgt gccgttgcca
    24661 gataacccac agccgacgcc agaatggcaa ccaacggcgc gccaatcatc atgttccaca
    24721 gcatatggtt ggtaatgttg tcgccgctgc cctctttgtt gagatacagt gggatcccgg
    24781 cctttttcag gctgagggtg accaccgcca gcgcaccgca aatgaggata aagcaaagcc
    24841 gtcccagcga accggagaat tcacggtcgt cgaggttatc gaacatcatc agcgccataa
    24901 tcagcggcac aataagcccg atgctcatca ggtagtagcg catcccacgg gaaacacgtt
    24961 cgcgcggcca gccaaaatga gcgataaaca agccgttcgg gcgggcaaag gtggcgcaaa
    25021 tcatcactac ccacagcagc ggcacggtgg ccgttacacc atcgccaatc gcgaccgcca
    25081 gcggataagg ccacgcctcg cgcaagccgt aacccagcgt catccacagc accggtaacg
    25141 gtgacgcgac gagaatcgac cagaaaagag tgcgcaacgt cagccagaag tgatcctgag
    25201 tcactttgcc aactttcgcc gccgaacgtt caagaaaacg ggtgaaatag cggcgcgagt
    25261 aaatactgca accgaccaga atcaacgcgc caaacagcgg caaaattgtc tctttgctgg
    25321 tcagcatcat cacactggct ttgcccaact gactgaaggt gtccagcgaa atgagacgac
    25381 gcagatcctg ggcgatttcc agcggccagg cgatggtcat cgggcgcacg tcagaggtcc
    25441 agaacagata gcggtgcgtt gcttcgttca cctctttcag cgcatcctcc agttgcccgt
    25501 tggagacttt cagcttggtc agttccaata gtagcgtgtc gccaccctgc aacaatgagt
    25561 tcagcaactc acgctgagtg cgcagttgtg cttccagaat acggttttgc tcggcagtca
    25621 gcggctgacc gtcggcctga tgaatttgcc gtagcagcgg ctgtttatta agcagatcct
    25681 cataacgtaa ccgttgcaca cgcaactgcg ccatttcggt atcaagctgt tgtggtttcg
    25741 gcatttccgg cagccgtgcc acctgcgccc gcagcgcttc gccgagcaga ttggacgatc
    25801 ccagccattg cgactgttca cgcagcgtat tcaacgcctg ccggacctgt aacgtctggc
    25861 tggcagcctg acgctgttgc gaggcaacga gatccatccg ctgcgcctgt tgattcaaag
    25921 ccgccgatag ttcgcggtta attttgaatt gcgcgacgat atctttcggc aaatcggcgc
    25981 tgttttctgc cagcaattcg gtactttcca gcgcccgctc cgcctcaagc tgacgttggc
    26041 tgtttaattg attacgcaag gcctgcaaat acgcatccag ttgctggctc tctttttccg
    26101 ccagctctga gcgtaagcgc gctaattcct ggcggttatt ggcagacagc tgcgccagct
    26161 ccagttcatc aacgagcgcc ttaagacgtg cagagtcaga ctgcaacgcg aaattttgtg
    26221 cctgattgag cggagtattg ccggtaagcg ttcccaggcg gcgctcgatc tcatttaact
    26281 gacggcgggc gtcggtttgc tgttgcggca gttgattcag cgaatcggca atctcgcggg
    26341 cgcgctcctg ctcttgctgg gcctgacggc ttttatccag caactggctg ctgacctgga
    26401 gaatttcctg attcagcgcg tcggtagaca ttcccggcga cacgctgcgc ggctcgtcac
    26461 gcatgttgtt taattgtgcg cgcagagtag cggagagttt cggataatta tcgataactt
    26521 gctgatattg tttgatgcgc tcaagggaac cttttcgttc ctcaagcgca tttaaggcag
    26581 actggagcgc ctctacgact tccggctgtg cgggtttcgc cgcttttgcc tgctccagtt
    26641 cctgagtgat ttgtttgcta tcgggggccg tcgcggcgta cgccccccaa ctgaggcacc
    26701 aggccatcag aaaagtgata atcaggcgca cgtcagcgtt tcctttgatg gattagacct
    26761 ggtctttttt gtcgtcaacc aatgggctgg cgtcgtgttc tgcttcgatc tcttcagcag
    26821 gaagcggggc aggttcagcg tctggcgtaa caaaggtttc ggtagatact gccagcggct
    26881 ggccaatttt cgtgacagac aggctttcca gttgctcaac cagattcact ttacccggtg
    26941 caaacaggtt gataacggtg gaaccgagtt taaagcgacc catttcctgg cctttcagca
    27001 gtgccacaga accgtcgttt tccccggcag gccaggtcca gcgcttgatg ataccttcgc
    27061 gcggcggcgt aatggtgccc gcccagaccg tctcaatgct gccaacaatc gtcgctccga
    27121 ccagaatctg cgccattggg ccaaattcgg tatcgaaaag gcaaatcacg cgttcgttac
    27181 gggcaaacag attcggcacg ttctgagccg tgagatggtt aacggagaag agatcgcccg
    27241 gcacgtagat catctcacgc agaataccgt tgcacggcat gtgtacgcgg tggtagtcac
    27301 gtggggagag gtaagtggtc acaaacgtac cgttgcggaa caggtccgcc atcagatagt
    27361 tgcctgccag cagggcttcg aggctgtagt tgtggccttt ggcttgcagg attttatctt
    27421 cttcgatttt acccaactgg ctgataacgc catcggcagg catgaccagt acattcggat
    27481 cggtatcgat tgggcgtact tcgtcacgca gcggacggac aaagaattcg ttaaaggtgc
    27541 ggtagctggc ggtgtccggc ttttgcgcct ctttcatgtc gaccttgtag tatttaacga
    27601 acagatcgat aaccagtttt gtcagccatc ctgcccgctt gcttgcgccc caacccgcca
    27661 ggcgagtaag ccatagtttc ggcagaatgt actgtagcga aagtttaaat gaatttaaca
    27721 aggtagcctc caggccattg ttttgtcgtt cctgatccgg cctacatgcc ggatcctgaa
    27781 aaaaagggga cgattctaac gacggttagc ttaattgtca gtcatccgta tcagaaaagt
    27841 ttttacgcgt ttttacctgc gccatgcttt ccagaatacg gtgatagttt tcgaaacggg
    27901 tttccgcgat tttcccttcc tcaaccgctt cccggatagc gcagcccgga tcggtatcgt
    27961 gtttgcaatc gcgatattta cacagaccta aatagtcatg gaattcgaca aagccctgag
    28021 tgatttgttc cggctccagg tgccagaggc cgaactcacg cactcctggg gagtcaatca
    28081 catcaccgcc gtgcgggaag tgatacagcc gagcggcggt cgtggtgtgc tgaccgagcc
    28141 ccgagttgtc agagacatcg ttggtcagga tctctttttg cagccccagc aacgcattca
    28201 gcaggctgga tttgccgacg ccagactgcc cggcaaaaat gctgatgcgc ccggtcaacg
    28261 cctcttccag cggttttagc ccatcctgag tatggctgga aaccatcaat acgcgataac
    28321 cgatattgcg gtagatatcc atctgctcgt tgacgaacgc catgccttcg tcgtccagca
    28381 ggtctatctt gttgagcaca ataatcggct caatctgcaa ggtttcgcag gccaccaggt
    28441 aacggtcgat aatattgagt gacagctccg gcaaaatggc ggagacaatg acaatctggt
    28501 cgatgttggc ggcaataggt tttacgccgt cgtagaaatc cggacgcgtc aacaccgagg
    28561 tacgctcatg caccgcttcc acgatccctt tgacatttac gccttccgcc gccggtttac
    28621 ccggacgcca gactacgcgg tcgccggtca ccagcgaacg gatggtacgg cgaatattgc
    28681 agcggtgaac gtcgccatcg gcggattcca catcagcgtg cataccaaag cggctgatga
    28741 cgataccttc atcaggctcg ccaaacagat tgtcgtcgta gtcgggcttc tccttagacg
    28801 ttttaagacg acgctggtga ttggcgttca cgcggcgctg ctggcctttg gagagtttat
    28861 ttttactcaa tcgtacagac tcctggtcgc ccctgatggg caaaacatct atgatacacg
    28921 caattgtgga tcaatatagt cactgtgaat gggtggaaaa tagcatgagt gccaatgaaa
    28981 acaacctgat ttggatcgat cttgagatga ccggcctgga tcccgagcgc gatcgcatta
    29041 ttgagattgc cacgctggtg accgatgcca acctgaatat tctggcagaa gggccgacca
    29101 ttgcagtaca tcagtccgat gaacagctgg cgctgatgga tgactggaac gtgcgcaccc
    29161 atacctccag cgggctggta gagcgcgtga aagcgagcac gatgggcgat cgggaagctg
    29221 aactggcaac gctcgaattc ttaaaacagt gggtgcctgc gggaaaatcg ccgatttgcg
    29281 gtaacagcat cggacaggac cgtcgtttcc tgtttaaata catgccggag ctggaagcct
    29341 acttccacta ccgttatctc gatgtcagca ccctgaaaga gctggcgcgc cgctggaagc
    29401 cggaaattct ggatggtttt accaagcagg ggacgcatca ggcgatggat gatatccgtg
    29461 aatcggtggc ggaactggct tactaccgcg agcattttat caagctgtaa aatttttcct
    29521 ggtcacgtaa gcgccggaat ccacttgcgg cggcgtgatt ttgacgctaa attgaacgtc
    29581 ttgctgataa tttcagcact tgagataaaa acgcaaaaaa aacttttttg gggggttgca
    29641 gagggaaaga tttctcgtat aatgcgcctc ccgtaacgac gcagaaatgc gaaaattacg
    29701 aaagcaaaat taagtagta
//
LOCUS       DACAOP010000054        28615 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.054, whole genome shotgun sequence.
ACCESSION   DACAOP010000054 DACAOP010000000
VERSION     DACAOP010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28615
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.054"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..265)
                     /locus_tag="IT892_002656"
     CDS             complement(<1..265)
                     /locus_tag="IT892_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135859.1"
                     /translation="MRYNGLNNMFFPLCLINDNHSVTSPSHTKKTKSDNYSKHHKNTL
                     IDNKALSLFKMDDHEKVIGLIQKMKRIYDSLPSGKITKETDRKI"
     gene            complement(443..2092)
                     /gene="actP"
                     /locus_tag="IT892_002657"
     CDS             complement(443..2092)
                     /gene="actP"
                     /locus_tag="IT892_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation/acetate symporter ActP"
                     /protein_id="HAP3135860.1"
                     /translation="MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVV
                     FTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYD
                     GLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
                     YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFG
                     ASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTA
                     GLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAG
                     HLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVF
                     KKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLS
                     MYWSKLTTRGAMMGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSITVAF
                     LGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH"
     gene            complement(2089..2403)
                     /locus_tag="IT892_002658"
     CDS             complement(2089..2403)
                     /locus_tag="IT892_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HAP3135861.1"
                     /translation="MNGTIYQRIEDNAHFRELVEKRQRFATILSIIMLAVYIGFILLI
                     AFAPGWLGTPLNPNTSVTRGIPIGVGVIVISFVLTGIYIWRANGEFDRLNNEVLHEVQ
                     AS"
     gene            complement(2603..4561)
                     /gene="acs"
                     /locus_tag="IT892_002659"
     CDS             complement(2603..4561)
                     /gene="acs"
                     /locus_tag="IT892_002659"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006816721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HAP3135862.1"
                     /translation="MSQIHKHTIPANIADRCLINPQQYEAMYQQSINVPDTFWGEQGK
                     ILDWIKPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDA
                     SQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
                     VIFGGFSPEAVAGRIIDSNSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVV
                     VLKRTGGKIDWQEGRDLWWHDLVEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVP
                     NWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINP
                     EAWEWYWKKIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVD
                     NEGNPLEGATEGSLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDG
                     YYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIYAYVTLN
                     HGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTS
                     NLGDTSTLADPGVVEKLLEEKQAIAMPS"
     gene            4954..6390
                     /gene="nrfA"
                     /locus_tag="IT892_002660"
     CDS             4954..6390
                     /gene="nrfA"
                     /locus_tag="IT892_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming nitrite reductase cytochrome
                     c552 subunit"
                     /protein_id="HAP3135863.1"
                     /translation="MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNET
                     FAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVR
                     ETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGC
                     ADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYF
                     DGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHG
                     KNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQ
                     SINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHM
                     HAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQ
                     IKAEKQDFIKTVIPQWEEQARKNGLLSQ"
     gene            6435..7001
                     /gene="nrfB"
                     /locus_tag="IT892_002661"
     CDS             6435..7001
                     /gene="nrfB"
                     /locus_tag="IT892_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418495.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase pentaheme
                     subunit"
                     /protein_id="HAP3135864.1"
                     /translation="MSVLRSLLTAGVLASGLLWSLNGITATPAAQASDDRYEVTQQRN
                     PDAACLDCHKPDTEGMHGKHASVINPNNKLPVTCTNCHGQPSPQHREGVKDVMRFNEP
                     MYKVGEQNSVCMSCHLPEQLQKAFWPHDVHVTKVACASCHSLHPQQDTMQTLSDKGRI
                     KICVDCHSDQRTNPNFNPASVPLLKEQP"
     gene            6998..7669
                     /gene="nrfC"
                     /locus_tag="IT892_002662"
     CDS             6998..7669
                     /gene="nrfC"
                     /locus_tag="IT892_002662"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase Fe-S protein"
                     /protein_id="HAP3135865.1"
                     /translation="MTWSRRQFLTGVGVLAAVSGTAGRVVAKTLNINGVRYGMVHDES
                     LCIGCTACMDACREVNKVPEGVSRLTIIRSEPQGEFPDVKYRFFRKSCQHCDHAPCVD
                     VCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVTKTADKCDFCRKTNL
                     QAGKLPACVEACPTKALTFGNLDDPNSEISQLLRQKPTYRYKLALGTKPKLYRVPFKY
                     GEVSQ"
     gene            7666..8622
                     /gene="nrfD"
                     /locus_tag="IT892_002663"
     CDS             7666..8622
                     /gene="nrfD"
                     /locus_tag="IT892_002663"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase subunit NrfD"
                     /protein_id="HAP3135866.1"
                     /translation="MTQTSAFHFESLVWDWPIAIYLFLIGISAGLVTLAVLLRRFYPQ
                     AGGADSTLLRTTLIVGPGAVILGLLILVFHLTRPWTFWKLMFHYSFTSVMSMGVMLFQ
                     LYMVVLVLWLAKIFEHDLLALQQRWLPKLGIVQKVLSLLTPVHRGLETLMLVLAVLLG
                     AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGAAVALIAMAIRQRSNPHSTEAQFVH
                     RMEIPVVWGEIFLLVAFFVGLALGDDGKVRALVAALGGGFWTWWFWLGVAGLGLIVPM
                     LLKPWVNRSSGIPAVLAACGASLVGVLMLRFFILYAGQLTVA"
     gene            8642..10360
                     /locus_tag="IT892_002664"
     CDS             8642..10360
                     /locus_tag="IT892_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HAP3135867.1"
                     /translation="MDVFLPEVGFLALLLSLGVNVLTPLTAFAGVRLRWPAMMRLTCI
                     GILAQFALLLLAFGVLTYCFLISDFSVIYVAQHSYSLLSWELKLAAVWGGHEGSLLLW
                     VLLLSAWSALFAWHYRQQTDPLFPLTLAVLSLMLAALLLFVVLWSDPFVRIFPPAIEG
                     RDLNPMLQHPGLIFHPPLLYLGYGGLMVAASVALASLLRGEFDGACARICWRWALPGW
                     SALTAGIILGSWWAYCELGWGGWWFWDPVENASLLPWLSATALLHSLSLTRQRGIFCH
                     WSLLLAIVTLMLSLLGTLIVRSGILVSVHAFALDNVRAVPLFSLFALISLASLALYGW
                     RARDGGPAVHFSGLSREMLILATLLLFCAVLLIVLVGTLYPMIYGLLGWGRLSVGAPY
                     FNRATLPFGLLMLVVIVLATFVSGKRVQLPALVAHAGVLLFAAGVVVSSVSRQEISLN
                     LQPGQQVTLAGYTFRFECLDLQAKGNYTSEKAIVALFDHQQRIGELTPERRFYEARRQ
                     QMMEPSIRWNGIHDWYAVMGEKTGPDRYAFRLYVQSGVRWIWGGGLLMIAGALLSGWR
                     GKKRDE"
     gene            10353..10736
                     /gene="nrfF"
                     /locus_tag="IT892_002665"
     CDS             10353..10736
                     /gene="nrfF"
                     /locus_tag="IT892_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfF"
                     /protein_id="HAP3135868.1"
                     /translation="MNKGLLTLLLLFTCFAHAQVVDTWQFANPQQQQQALNIASQLRC
                     PQCQNQNLLESNAPVAVSMRHQVYSMVAEGKNEVEIIGWMTERYGDFVRYNPPLTGQT
                     LVLWALPVVLLLLMALILWRVRAKR"
     gene            10733..11329
                     /gene="nrfG"
                     /locus_tag="IT892_002666"
     CDS             10733..11329
                     /gene="nrfG"
                     /locus_tag="IT892_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfG"
                     /protein_id="HAP3135869.1"
                     /translation="MKQPKIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRQRD
                     PLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQL
                     RGENAELYAALATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANY
                     AQAIELWQKVMDLNSPRVNRTQLVESINMAKLLQRRLD"
     gene            11671..12984
                     /gene="gltP"
                     /locus_tag="IT892_002667"
     CDS             11671..12984
                     /gene="gltP"
                     /locus_tag="IT892_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate:proton symporter GltP"
                     /protein_id="HAP3135870.1"
                     /translation="MKNIKFSLAWQILFAMVLGILLGSYLHYHSDSRDWLVVNLLSPA
                     GDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIILGITL
                     ANVFQPGAGVDMSQLATVDISKYQSTTEAVQSSSHGIMGTILSLVPTNIVASMAKGEM
                     LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVT
                     VANFGFSSLWPLAKLVLLVHFAILFFALVVLGIVARLCGLSVWILIRILKDELILAYS
                     TASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID
                     LSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMA
                     RTALNVVGNALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ"
     gene            complement(13063..13752)
                     /locus_tag="IT892_002668"
     CDS             complement(13063..13752)
                     /locus_tag="IT892_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HAP3135871.1"
                     /translation="MKKIIALMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADS
                     WFSSGDLSKAEYWAQKAADSGDADACALLAQIKITNPVSLDYPQAKVLAEKAAQAGSK
                     EGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKA
                     DDDKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDT
                     GCEEFEKLTNG"
     gene            complement(13846..15993)
                     /gene="fdhF"
                     /locus_tag="IT892_002669"
     CDS             complement(13846..15993)
                     /gene="fdhF"
                     /locus_tag="IT892_002669"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(15574..15576),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HAP3135872.1"
                     /translation="MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLK
                     GYYGWDFINDTQILTPRLKTPMIRRQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDA
                     IQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNA
                     INEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIAL
                     KNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYRKIVEGYTPESVEDITGVSAS
                     EIRQAARMYAQAKSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAGVNPVRG
                     QNNVQGACDMGALPDTYPGYQYVKDPANREKFAKAWGVESLPAHTGYRISELPHRAAH
                     GEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGE
                     HEGVFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHL
                     CPDFYGATYEKMGELGFIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPI
                     DKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTEDAKRLGIEDEA
                     LVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCA
                     VRVEPIADQRAAEQYVIDEYNKLKTRLREAALA"
     gene            complement(16191..17657)
                     /gene="mdtP"
                     /locus_tag="IT892_002670"
     CDS             complement(16191..17657)
                     /gene="mdtP"
                     /locus_tag="IT892_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MdtP"
                     /protein_id="HAP3135873.1"
                     /translation="MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKL
                     ADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLSGSHTLAEAKLREEKAQSQADLLDA
                     GSQLQVAALGMLNRQRVSANGFLSPYSMDAPALGMDGPYYTEATVGLFAGLDLDLWGV
                     HRSAVAAAIGAHNAALAETAAVELSLATGVAQLYYSMQASYQMLDLLEQTHDVIDYAV
                     KAHQSKVAHGLEAQVPFHGARAQILAVDKQIVAVKGQITETRESLRALIGAGASDMPE
                     IRPVALPQVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAF
                     FGLDSIHLHTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVL
                     NAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPV
                     LAEEMSLLMLDSRRVIQSIQLMKSLGGGYQAGPVVEKK"
     gene            complement(17654..19705)
                     /gene="mdtO"
                     /locus_tag="IT892_002671"
     CDS             complement(17654..19705)
                     /gene="mdtO"
                     /locus_tag="IT892_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter permease subunit
                     MdtO"
                     /protein_id="HAP3135874.1"
                     /translation="MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVI
                     LISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATVLEIGSLFLIYKWSYGEP
                     LIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCI
                     VVGLYPTLLMTLIGVLWFPSRAISQMHQALNDRLDDAISHLTDSLVPLPETRIEREAL
                     ALQKLNVFCLADDANWRTQNAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKL
                     ASEINKLQHAVAEGQCWQSDWRISESEAMAARECNLENICQTLLQLGQMDPNTPPTPA
                     AKPPSMAADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVG
                     SSYQKMVLRFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERS
                     SYIGTQMVVTFALATLENVFGPVYDLVEIRDRALGIIIGTVVSAVIYTFVWPESEART
                     LPQKLAGTLGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVALERQLD
                     SEERALLIERSQTVIRQGRDLLHAWDATWNSAQALDNALQPDRAGQFADALEKYAAGL
                     ATALSRSPQITLEETPASQAILPTLLKQEQHVCQLFARLPDWTAPALTPATEQAQGAT
                     Q"
     gene            complement(19705..20736)
                     /gene="mdtN"
                     /locus_tag="IT892_002672"
     CDS             complement(19705..20736)
                     /gene="mdtN"
                     /locus_tag="IT892_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter periplasmic adaptor
                     subunit MdtN"
                     /protein_id="HAP3135875.1"
                     /translation="MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYA
                     SADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQI
                     MLTQRSVDAQQFGADSVNATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTA
                     QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGR
                     VISLKTSVGQFASAMRPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKT
                     FEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGA
                     SAVANLEPQ"
     gene            complement(20755..21030)
                     /locus_tag="IT892_002673"
     CDS             complement(20755..21030)
                     /locus_tag="IT892_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135876.1"
                     /translation="MPTVLSRMAMQLKKTAWIIPVFMVSGCSLSPAIPVIGAYYPSWF
                     FCAIASLILTLITRRVIQRANINLAFVGIIYTALFALYAMLFWLAFF"
     gene            complement(21239..23224)
                     /gene="yjcS"
                     /locus_tag="IT892_002674"
     CDS             complement(21239..23224)
                     /gene="yjcS"
                     /locus_tag="IT892_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl sulfatase YjcS"
                     /protein_id="HAP3135877.1"
                     /translation="MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVN
                     QNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDANGKVYYRADDYKFDINAAAPETV
                     NPSLWRQSQINGISGLFKVTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAA
                     LDLYFQHRPQKPIVAVIYTHSHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISE
                     NVLAGNIMSRRALYSYGLLLPHNAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMI
                     IDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFYTLRGAKTRDTSKWT
                     EYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTIKYIHDQTLHLANQGYT
                     MNEIGDMIKLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMG
                     KRYVQALGGSARVINLAQEANKQGDYRWSAELLKQVIAANPGDQVAKNLQANNFEQLG
                     YQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMAVRLDSAKA
                     AGKNISLNFNMSNGDNLNLTLNDSVLNYRKTLQPQADASFYISREDLHAVLTGQAKMA
                     DLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTPN"
     gene            complement(23497..24426)
                     /gene="alsK"
                     /locus_tag="IT892_002675"
     CDS             complement(23497..24426)
                     /gene="alsK"
                     /locus_tag="IT892_002675"
                     /EC_number="2.7.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allose kinase"
                     /protein_id="HAP3135878.1"
                     /translation="MQKQHNVVAGVDMGATHIRFCLRTAEGETLHCEKKRTAEVIAPG
                     LVSGIGEMIDEQLRRFNARCHGLVMGFPALVSKDKRTIISTPNLPLTAADLYDLADKL
                     ENTLNCPVEFSRDVNLQLSWDVVENRLTQQLVLAAYLGTGMGFAVWMNGAPWTGAHGV
                     AGELGHIPLGDMTQHCACGNPGCLETNCSGMALRRWYEQQPRNYPLRDLFVHAENAPF
                     VQSLLENAARAIATSINLFDPDAVILGGGVMDMPAFPRETLVAMTQKYLRRPLPHQVV
                     RFIAASSSDFNGAQGAAILAHQRFLPQFCAKAP"
     gene            complement(24410..25105)
                     /locus_tag="IT892_002676"
     CDS             complement(24410..25105)
                     /locus_tag="IT892_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allulose-6-phosphate 3-epimerase"
                     /protein_id="HAP3135879.1"
                     /translation="MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTL
                     SPFFVSQVKKLATKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEI
                     RRHDMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKLAELKAW
                     REREGLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQIL
                     AAKSEVQPHAKTA"
     gene            complement(25116..26096)
                     /gene="alsC"
                     /locus_tag="IT892_002677"
     CDS             complement(25116..26096)
                     /gene="alsC"
                     /locus_tag="IT892_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter permease"
                     /protein_id="HAP3135880.1"
                     /translation="MGFTTRVKSEASEKKPFNFALFWDKYGTFFILAIIVAIFGSLSP
                     EYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGV
                     DPFLAAMIGGVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYG
                     FSFDFVNFFAASVIGIPVPVIFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGI
                     DVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSFFGGK
                     GRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVALDRLISK"
     gene            complement(26075..27607)
                     /locus_tag="IT892_002678"
     CDS             complement(26075..27607)
                     /locus_tag="IT892_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose import ATP-binding protein AlsA"
                     /protein_id="HAP3135881.1"
                     /translation="MATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGK
                     STLMKVLSGIHEPTKGTITINNISYNKLDHKLAAQLGIGIIYQELSVIDELTVLENLY
                     IGRHLTKKICGVNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL
                     MLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVM
                     KDGSSVCSGIVSDVSNDDIVRLMVGRELQNRFNAMKENVSNLAHETVFEVRNVTSRDR
                     KKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLD
                     AVKKGMAYITESRRDNGFFPNFSIAQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQ
                     RELLALKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYK
                     VMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMSEEEIMAWALP
                     QE"
     gene            complement(27734..>28615)
                     /gene="alsB"
                     /locus_tag="IT892_002679"
     CDS             complement(27734..>28615)
                     /gene="alsB"
                     /locus_tag="IT892_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose transporter substrate-binding protein"
                     /protein_id="HAP3135882.1"
                     /translation="TSAFAAAEYAVVLKTLSNPFWVDMKKGIEDEAKTLGVSVDIFAS
                     PSEGDFQSQLQLFEDLSNKNYKGIAFAPLSSVNLVMPVARAWKKGIYLVNLDEKIDMD
                     NLKKAGGNVEAFVTTDNVAVGAKGASFIIDKLGAEGGEVAIIEGKAGNASGEARRNGA
                     TEAFKKASQIKLVASQPADWDRIKALDVATNVLQRNPNIKAIYCANDTMAMGVAQAVA
                     NAGKTGKVLVVGTDGIPEARKMVEAGQMTATVAQNPADIGATGLKLMVDAEKSGKVIP
                     LDKAPEFKLVDSILVTQ"
BASE COUNT         6559 a         7472 c         7598 g         6986 t
ORIGIN      
        1 gtattttcct gtccgtttct ttcgtgattt ttcctgatgg taaactatca taaattcttt
       61 tcattttctg aatcaagcct atcacttttt catgatcatc cattttgaaa agagagaggg
      121 ctttattgtc aattaacgtg tttttatgat gtttgctgta attatctgat tttgttttct
      181 ttgtatgtga tggacttgtg acagagtggt tatcgttaat caggcaaaga gggaaaaaca
      241 tattatttaa accattatag cgcataaaat atccttataa ttaacaagaa agaaaaggca
      301 tattctctgc attatcattt tctacgactg tcaaaaatcg ctcatttttt aatgagttta
      361 tttgtttaat attatgggaa aaggtgatgc atttgggaga ggaagagtat tccccggtca
      421 gacgaccggg gaaggggaga gattaatgcg cgcggccttg ctcaacgcca aagccggtct
      481 gggagcggat aaactgcgcg cggaacagtt cacgctcacg cgcgccttcc gctgagttat
      541 cggttgccga gaagaaccag atgccgagga atgccacggt gatagagaac agcgccgggt
      601 attcatacgg gaagatggct ttttcgtgac caaggatctg tacccaaatc gtcgggccga
      661 ggatcatcag tactactgcg gtaatcagcc ccagccagcc acccatcatc gcgccacgcg
      721 tggtcagttt cgaccagtac atagaaagca gaatgatcgg gaagttacag ctcgccgcga
      781 tggcaaacgc cagccccacc ataaaggcga tgttctgatt ctcaaacagc acgccgagga
      841 taatcgcaat cacgccgagg atcagtacgg tgatttttga tacccgcagc tcttcacgtt
      901 cggtcgcgcc ttttttgaag acgttagcgt acaagtcatg cgaaaccgcg gatgcgcccg
      961 ccagcgtcag acccgcaacc accgcgagga tagtggcgaa agcaaccgct gaaataaaac
     1021 cgaggaacag gttgccgccc actgcattcg ccaggtgaac ggccgccatg ttgttaccac
     1081 caatcagatg gcccgccgcg tctttatatt ccggattcgc accaaccagc atgatcgcgc
     1141 cgaagccgat aataaaggtc agaatataga agtagcccat aaacccggtg gcgtagaaca
     1201 cgctcttacg tgcttcgcgg gcatcgctga ctgtaaagaa gcgcatcaga atgtgcggca
     1261 agcccgccgt accaaacatc agtcccagac ccagagagag cgcggagatc ggatctttca
     1321 ccagcccgcc cggcttcatg atgtcgacac ctttcgggtg taccgccatc gcttcactga
     1381 acagattgtt gaagctaaag ccgacgtgtt tcatcaccat aaaggccata aagctggcac
     1441 cgaacagcaa cagcacggct ttgataattt gcacccaggt ggtcgccagc atgccgccga
     1501 acaggacgta catcatcatc agcacgccga ccagcaccac cgcaatgtga tagttaaggc
     1561 caaacagcag ctcgatcagt ttacctgcgc ccaccatctg ggcgataagg taaagcgcca
     1621 ccaccaccag agaaccacag gccgaaagaa tacgaatcgg cccttgtttc agacggtaag
     1681 aggccacatc ggcaaaggtg tagcgcccca ggttacgcag acgttcggca atcaggaaca
     1741 aaatgatcgg ccagcccacc aggaagccca gcgagtaaat taagccgtca tagccggagg
     1801 taaacaccag cgcggagatc cccaagaatg aggcggcgga catatagtcc ccggcaatcg
     1861 ccagcccgtt ctggaagcca gtgatattgc cgcctgcggt gtagtagtcg ctacgagaac
     1921 gtacgcgttt tgatgcccag taggtaatgc cgagcgtaaa cacgacgaaa atcaggaaca
     1981 taataatcgc ctgccagttc gttggctggc gctctacggc cccgctaata gcatccgcgg
     2041 cgttagctgc gaaagggagt gtggcggcaa gcgccgtcag aactcttttc atgatgcttg
     2101 tacctcatgc aggacttcat tattaagacg gtcgaattcg ccgttcgccc gccagatgta
     2161 gataccggtg agaacaaagg agatcacaat cactccaaca ccaattggaa taccgcgtgt
     2221 gacgctggtg ttcggattca gcggcgtgcc cagccagccg ggcgcgaagg cgatcagtaa
     2281 aataaagccg atataaactg ccagcataat aatcgacagg atggtggcaa accgttgccg
     2341 tttttcgact aactccctga aatgcgcatt gtcttctatc cgctgataaa tagtgccatt
     2401 catcacagat tctccagagg taatgtaggg attgttttaa ttcccgctcc cttatgggag
     2461 aaggttaacg ctcgggtaac ccttgccgaa tgtaggccgg ataaggcgtt tacgccgcat
     2521 ccggcaatca atgcctgatg cgacgctgtc gcgtcttatc aggcctacaa accgttaccg
     2581 actcgcatcg ggcaattgtg ggttacgatg gcatcgcgat agcctgcttc tcttcaagca
     2641 gcttctcgac tacgccagga tcggcaagcg tcgaggtatc gcccaggttg ctggtatcgc
     2701 ccgccgcaat tttgcgcaga atacggcgca taattttgcc ggagcgggtt ttaggcaggg
     2761 agtcggtcca gtgcagcacg tctggcgtcg ccagcgggcc aatctcttta cgcacccagt
     2821 tgcggacttc tgcgtacagt tctggtgacg gttcctcccc gtgattaagc gtgacgtagg
     2881 cgtagatcgc ctgaccttta atattgtgcg gaatacctac tacggcggct tcggcaatct
     2941 tcggatgcgc caccagcgcc gactcaatct ctgccgtccc cagacggtga ccggagacgt
     3001 tcagcacgtc gtccacacgc ccggttatcc agtaatagcc atcttcatcg cgacgcgcgc
     3061 cgtcgccgct gaaatacata tttttgaagg tggagaagta ggtctgttca aaacgttcgt
     3121 gatcgccaaa cagcgtacgc gcctgacccg gccaggagtc ggtgattacc aggctacctt
     3181 cggtggcccc ctccagcggg ttaccttcgt tatcgaccag cgccggttgc acgccgaaga
     3241 acggacgtgt tgccgaaccg gctttcagct cggtagcgcc aggcagcggg gtgatcatga
     3301 aaccgccggt ttcggtctgc caccaggtat cgaccaccgg acatttctcg ttgccgattt
     3361 ttttccagta ccactcccac gcttccgggt taattggctc gcccacggaa ccgagaatgc
     3421 gcagcgacga acggtcggtg ccttcgatcg ctttatcgcc ttccgccatc agcgcgcgga
     3481 tcgccgtggg tgcggtatag agaatattga cctgatgctt gtccaccacc tgcgccatac
     3541 gggcaggcgt cggccagttg ggtacgcctt caaacatcag cgtggtcgca ccgcaggcca
     3601 gcgggccgta cagcaagtaa ctgtgtccgg tcacccagcc cacatcggcg gtgcaccagt
     3661 agatatcacc cggatgataa tcaaagacat atttaaaggt cagcgccgcg tacaccagat
     3721 aaccgccggt agtatgcagc acaccttttg gcttaccggt agaaccggag gtgtagagaa
     3781 taaacagcgg atcttcggcg ttcatctctt ccgcctggtg ctgatcgctc gcttgctcaa
     3841 ccaggtcgtg ccaccacagg tcgcgccctt cctgccagtc aattttcccg ccagtacgct
     3901 tcagtaccac cacatgctct acgctggtga cgttcgggtt tttcagcgcg tcatcaacgt
     3961 ttttcttcag cggaatactg cgcccggcac gcacaccttc gtcggaagtg atcaccagtc
     4021 gtgagttgga atcaataatg cgcccggcaa cggcttccgg cgagaagccg ccgaaaatca
     4081 ccgaatgcac cgcgccaatg cgggcgcagg ccagcatcgc aaccgcggct tccggcacca
     4141 tcggcatata aatcgccacc acatcacctt ttttaatgcc cagctcgagc agggtattgg
     4201 cgaagcggca gacgtcgcgg tgcagctctt tatagctgat atgtttgctc tggctggcgt
     4261 cgtcgccttc ccagatgatg gcggtacgat cgccgttttc ttgcagatgg cggtcaaggc
     4321 agtttgccgc cagattcagc gtgccgtcct cgtaccattt aatggacaca ttaccggggg
     4381 caaaggaggt gtttttcacc ttctggtaag gtttgatcca gtcaagaatt tttccctgtt
     4441 cgccccagaa ggtatcaggt acgttaatag attgttgata catcgcctcg tactgctgag
     4501 ggtttatcag gcaacggtct gcgatgttgg caggaatggt gtgtttgtga atttggctca
     4561 tgcttttgtt ctccttgtag gatgttaata atatgtggca taagcgttaa atgtaggggt
     4621 attggcagtt ttgtttagta tttgggcgac agatcacgca aaagtagaat tgtgcaaata
     4681 aacggcaggg taatttttga aggtcagcaa caaaagttga ttaattcttt gaggaacatg
     4741 cagttatgca tgctgttgaa aaagaggaag atactgacta actctaaagt ggtattttac
     4801 atgcacttac aattgattaa agacaacatt cacagtgtgg ttatttgtta cacatagggg
     4861 cgagcaatgt catgacagtg taggtgcggt tactgtcgtg aaaaacaata aaaaccgcca
     4921 ttgcaacaat ggcgcaattc ggatgaagcc cctatgacaa ggataaaaat aaacgcacgc
     4981 cgtatcttca gcttattgat tccttttttc tttttcactt ctgttcacgc tgaacaaacg
     5041 gctgctcccg caaaacctgt aactgtggaa gcgaagaatg aaacctttgc cccgcagcat
     5101 cccgatcaat atctctcctg gaaagccacc tcggaacagt cagagcgtgt tgacgccctg
     5161 gcggaagatc cacggctggt gatcctgtgg gcggggtatc ccttctcgcg cgattacaac
     5221 aagccgcgtg gacatgcttt tgctgtgacc gatgtgcgtg aaaccctgcg taccggtgcg
     5281 ccgaaaaacg ctgaagatgg tccgctaccg atggcatgct ggagttgtaa aagcccggat
     5341 gtggcgcgtc tgatccagaa agacggcgaa gatggctact tccacggtaa atgggcgcgc
     5401 ggcggtccgg aaatcgtcaa caacttaggt tgtgccgatt gccataacac cgcctctcca
     5461 gagttcgcca aaggcaaacc ggagttaacc ctttcccgtc cgtatgcggc tcgcgcgatg
     5521 gaagccattg gtaaaccttt tgagaaagcc ggacgtttcg accagcaatc gatggtttgc
     5581 ggtcagtgcc atgtggagta ttacttcgac ggcaaaaaca aagcggttaa attcccgtgg
     5641 gatgacggca tgaaagtcga aaatatggag cagtattacg acaaaattgc cttctctgac
     5701 tggactaact ccctgtcgaa aacgccaatg ctgaaagcgc agcacccgga atatgaaacc
     5761 tggacagcgg gcattcacgg taaaaacaac gtgacctgta tcgactgcca tatgccaaaa
     5821 gtgcagaacg ccgaaggcaa actctacacc gaccataaaa ttggtaatcc gtttgataac
     5881 ttcgcccaga cttgtgcgaa ctgccatacc caggacaaag ctgccttgca aaaagtggtc
     5941 gcggaacgta agcagtcgat taacgacctg aaaatcaagg ttgaagatca actggttcac
     6001 gctcacttcg aagcgaaagc agcgctggat gcaggcgcga cggaagctga aatgaagcca
     6061 attcaggacg atatccgtca tgcccagtgg cgctgggatc tggcgatcgc ttcccacggc
     6121 attcatatgc acgcaccgga agaaggttta cggatgctcg gtacggcgat ggataaagcg
     6181 gcggatgcac gcaccaaact ggcgcgcctg ctggcgacca aaggcatcac ccatgaaatc
     6241 cagatcccgg atatctcaac caaagagaaa gcccagcagg ccattggcct gaacatggaa
     6301 caaatcaagg ccgagaagca ggacttcatc aaaacggtga tcccgcagtg ggaagaacag
     6361 gcacgtaaaa acggtctgtt aagccaataa ccccgttccg cctcgcaagg ggcggaaaac
     6421 acaatggagt gaatatgagc gtattacgtt cgttattaac tgccggggtg ctggcgtcgg
     6481 gcctgttgtg gagcctgaac ggaattaccg ctacccctgc ggcgcaggca tctgatgatc
     6541 gctacgaagt tacccagcag cgtaacccgg atgccgcctg tctggactgt cataaaccag
     6601 ataccgaagg tatgcatgga aaacatgctt ccgttatcaa cccgaataac aaactgccgg
     6661 tcacctgcac caactgtcac ggccagccat caccgcaaca ccgcgaaggg gtgaaagatg
     6721 tgatgcgctt taacgagccg atgtacaagg ttggagagca gaacagcgtc tgtatgtcct
     6781 gtcatctgcc ggaacagttg caaaaagcgt tctggccgca cgatgtccac gtaaccaaag
     6841 tggcgtgcgc cagctgccat tccctgcatc cacagcaaga tacgatgcag acgttaagtg
     6901 acaaaggacg gattaagatt tgcgtcgatt gccacagcga tcagcgcacc aatccgaact
     6961 ttaacccggc gtctgttccg ttgcttaagg agcagccatg acctggtctc gtcgccagtt
     7021 tctcaccggc gtcggcgtgc tggcagccgt cagcggcacc gcagggcgcg tggtggcgaa
     7081 aacgttgaat atcaatgggg tgcgttacgg catggtgcat gacgagtcgt tatgcatcgg
     7141 ctgtaccgcc tgtatggatg cttgtcggga agtgaacaag gtgccggaag gcgtctcgcg
     7201 cctgacgatt attcgtagcg agccgcaggg cgaatttcct gatgtgaaat atcgcttctt
     7261 ccgtaagtct tgccagcact gcgatcatgc gccgtgcgtt gacgtctgcc cgaccggtgc
     7321 gtcttttcgc gatgctgcca gtgggattgt cgatgttaat ccggatctct gcgtcggttg
     7381 tcagtactgc atcgccgcct gtccgtaccg cgtgcgcttt atccatccgg tcacgaagac
     7441 ggcggacaaa tgcgatttct gccgtaagac caatttgcag gccggtaagt tgcccgcgtg
     7501 cgttgaagct tgcccgacca aggcgctgac gtttggcaat ctggacgatc ccaacagtga
     7561 gatttcgcaa ctgctgcgcc agaagcccac ttaccgctac aagctggcgc tgggaaccaa
     7621 accgaagctg taccgcgtac cgtttaaata cggggaggtg agccaatgac gcagacttcc
     7681 gcatttcatt ttgaatcgct ggtgtgggac tggccgattg ccatctacct gtttttgatt
     7741 ggtatttctg ctggtctggt gacgctggcc gtgctgttac gtcgcttcta cccgcaggcg
     7801 ggcggtgcag acagtacgtt gctgcgcacc acgctgattg tcgggccggg cgcggtgatc
     7861 ctcggtctgt tgatcctcgt cttccacctg acaagaccgt ggaccttctg gaagctgatg
     7921 ttccactaca gttttacctc ggtgatgtcg atgggggtga tgctgtttca gctctacatg
     7981 gtggtgctgg tgctgtggct ggcgaaaatc tttgaacatg atttgcttgc cctgcaacaa
     8041 cgctggttgc cgaagctggg gatcgtgcaa aaggttctga gcctgctgac gcccgttcat
     8101 cgcggactgg aaacattgat gctggtgctg gcggtgttgt tgggggctta taccggcttt
     8161 ctgctgtcgg cgctgaaatc gtatccgttc ctcaataacc cgatcctgcc ggtgctgttc
     8221 ctcttctccg gcatctcgtc cggtgcggcg gtggcgctga tcgccatggc gatacgccaa
     8281 cgcagtaacc cgcattccac ggaagcgcag tttgtacacc gtatggaaat ccctgtggta
     8341 tggggtgaaa tcttcctgct ggtggcgttt tttgtcggtc tggcgctggg cgatgacggt
     8401 aaagttcgtg cgctggtggc ggcattaggt ggcggtttct ggacgtggtg gttctggctt
     8461 ggtgtcgccg ggctggggct gattgtgcca atgctgctca aaccgtgggt caatcgcagt
     8521 tccggcattc ctgccgtgct ggcggcgtgt ggggccagtc tggtcggcgt gttgatgctg
     8581 cgctttttca ttctctacgc cggacagttg acggtggcgt aagccagaaa agaggtggtt
     8641 tctggacgta ttccttcctg aagtcggttt tctggcgttg ttgttaagtc tcggggtcaa
     8701 cgtgttgacc ccgttgacgg ccttcgcggg agtgcggttg cgctggcctg ccatgatgcg
     8761 actcacttgc atcggcattc tggcgcagtt cgcgctcctg ctgctcgcct ttggcgtact
     8821 gacgtattgt tttctcatca gcgatttctc ggtcatttat gtcgcgcaac atagctatag
     8881 cctgctgtcg tgggaactca agctggcagc ggtgtggggc ggccatgaag gttcgctgct
     8941 gctttgggtg ctgctgcttt ccgcctggag cgcgctgttt gcctggcatt atcggcagca
     9001 aaccgatccg ctatttccgc tgacgttagc cgttttatct ctcatgctcg ccgcactgct
     9061 actgtttgtg gtgctgtggt ccgatccctt cgtgcggata tttccaccag caatcgaagg
     9121 ccgcgatctc aatccgatgc tgcaacatcc cggtcttatc tttcatccac cgctgcttta
     9181 ccttggctat ggcggtttga tggtagcggc gagcgtggcg ctggcgagtc tactgcgcgg
     9241 cgagtttgat ggtgcctgcg cccgaatttg ctggcgctgg gcgttacctg gctggagtgc
     9301 attaacggcg gggatcatcc tcggttcctg gtgggcctac tgcgaactcg gctggggcgg
     9361 ctggtggttc tgggatccgg tggaaaacgc ctctttatta ccctggcttt ctgccactgc
     9421 gctgctgcac agtttgtccc tgacacgcca gcgggggatt ttttgccact ggtcgctgtt
     9481 gctggcgata gttactctga tgctgtcgct gctgggcacc ttaattgtcc gttctggcat
     9541 tctggtttcg gttcatgcgt tcgcgctgga taacgtccgc gccgtgccgt tgttcagcct
     9601 gtttgcactg attagccttg cgtctctggc tctgtatggc tggcgagcgc gggacggtgg
     9661 cccggcggtg catttttcgg ggttatcgcg ggaaatgtta atcctcgcta cgctgttgct
     9721 gttttgcgca gtgctactga tcgtgctggt gggaacgctt tatccgatga tttacggcct
     9781 gctgggctgg ggacgcctct ccgttggcgc gccgtatttt aaccgcgcga cgttaccgtt
     9841 tggtctgttg atgctggtgg tgattgtgct ggcgacgttt gtctctggca aacgcgtgca
     9901 gcttccggcg ctggtagctc atgcgggcgt gctgttattt gccgctgggg tcgtggtctc
     9961 cagcgtcagc cgtcaggaga tcagcctgaa tttacagccg ggtcagcagg tgacgctggc
    10021 aggatacacc ttccgttttg agtgcctcga tctacaagcc aaaggcaatt acaccagcga
    10081 aaaagcgata gtggcactgt ttgaccatca gcaacgcatt ggtgaactga cgccggagcg
    10141 gcgtttttat gaagcacgcc gtcaacaaat gatggaaccg tcaattcgct ggaacggcat
    10201 ccatgactgg tatgcggtca tgggggagaa aactgggccg gatcgttacg cttttcgttt
    10261 gtatgtacaa agcggtgtgc gctggatctg ggggggagga ttgttgatga ttgcgggcgc
    10321 attgttaagc ggatggcggg ggaagaagcg cgatgaataa agggcttctc acgctactgc
    10381 tgttatttac ctgttttgcg cacgctcagg tcgtagacac ctggcaattc gccaatccgc
    10441 aacaacagca acaggcgtta aatattgcca gccagttacg ttgtccgcag tgccagaatc
    10501 aaaacttact ggaatccaac gcgccggtgg ctgtcagtat gcgccatcag gtttacagca
    10561 tggtggcgga ggggaagaac gaagtcgaaa tcattggctg gatgaccgaa cgctacggag
    10621 attttgttcg ctataaccca ccgttaacgg gtcagacgct ggtgttatgg gcgctgccag
    10681 tggtgttgtt actgctgatg gcactgatcc tctggcgagt gagggcgaag cgatgaaaca
    10741 gcccaaaata ccggtgaaaa tgctgacaac actcacgata ttgatggtat ttctctgtgt
    10801 cggcagttat ctgttaagcc caaaatggca ggcggtacgt gcggagtatc agcgtcagcg
    10861 cgatccgcta catcagtttg ccagccagca aaccccggaa gcgcagcttc aggcattgca
    10921 ggataaaatc cgcgctaatc cacaaaacag cgaacagtgg gcgttactgg gcgagtacta
    10981 tctgtggcaa aacgattaca gcaattcgtt gctggcgtac cgtcaggcgt tgcaactacg
    11041 tggtgagaac gctgaactgt atgcggcgct ggcgacggtg ctttattacc aggccagcca
    11101 gcatatgacc gcccagactc gcgcaatgat cgacaaagcc ctcgcgctgg acagtaatga
    11161 aatcaccgcc ctgatgctgc tggcttccga tgcgtttatg caggcgaact acgcgcaagc
    11221 catcgaacta tggcaaaaag tgatggatct caactcaccg cgagttaacc gaacacagct
    11281 ggttgagtcg attaatatgg cgaaattgtt gcagcggaga ttggattaat catctggtga
    11341 tgaagattat gtcattgagc tgcataaaaa ataatcgaat gaacatatgc caaaaataat
    11401 cactaatcag tattattgca gattaaacaa ataaaaatct ttccataaca aatggttatt
    11461 cattaatcct gccataaact cgcgttatta tgcattaatg cagcgaaaag ctctgttgtt
    11521 aaagggttgc gcaacatacc gcgcaaatga tactgatcat aagcgttaaa aaaatctaca
    11581 aaccaacgca acacaattca tgccctggca gtatgtcacg ttctcgcgtt tctgaacggg
    11641 gaacggcgct ccattgagga agtcattcat atgaaaaata taaaattcag cctggcctgg
    11701 cagattctgt ttgctatggt gctgggcatt ctcctgggaa gctacctgca ctaccatagc
    11761 gacagccgcg actggctggt cgtcaatttg ctctctccgg cgggtgatat cttcatccat
    11821 ctgattaaaa tgattgttgt gccgattgtg atctccacgc tggtggtggg tatcgcgggt
    11881 gttggtgatg ccaaacagct cgggcgtatt ggcgcgaaaa ccattatcta cttcgaggtg
    11941 atcaccaccg tcgccatcat tttggggatc actctggcga acgtcttcca gcccggtgcc
    12001 ggggtggata tgtcgcagtt ggcgaccgtc gatatctcga aatatcagag cactacggaa
    12061 gcggtacaaa gcagttccca cggcattatg ggcacgattt tgtcgctggt gccgacgaac
    12121 attgtggcgt cgatggcgaa aggcgaaatg ctgccgatca tctttttctc ggtgctgttt
    12181 ggtctggggc tttcttccct gcccgcgacg catcgtgaac cgctggtgac cgtgttccgc
    12241 tccatctctg aaaccatgtt taaagtgact cacatggtga tgcgttatgc accggtgggt
    12301 gtgtttgcgc tgattgcggt gacggtggct aactttggtt tctcgtctct gtggccactg
    12361 gcgaaactgg tgctgctggt gcatttcgcc attctgttct tcgcgctggt agtgctggga
    12421 attgtggcgc gcctgtgcgg gttaagcgtc tggatcctga ttcgtattct gaaagatgag
    12481 ctgattctgg cgtactccac tgccagctct gaaagcgtgc tgccgcgaat tattgagaag
    12541 atggaagcct acggagcacc ggcgtcgatc accagtttcg tggtgccgac cggttactct
    12601 tttaaccttg atggttcgac gctgtatcaa agtattgccg ctatcttcat cgcgcagttg
    12661 tatggcattg acctgtccat ctggcaggaa atcattctgg tgctgacgct gatggtgacc
    12721 tcgaaaggga ttgctggcgt gcctggcgtg tcgtttgtgg tgttgctggc aacgctgggt
    12781 agcgtaggta ttccgctgga aggtctggcg tttattgctg gtgttgaccg tatcctcgac
    12841 atggcgcgta ctgcgctgaa cgtggtgggt aatgcgctgg cggtgctggt gattgccaag
    12901 tgggaacaca aatttgaccg taagaaagcg ctggcttatg agcgtgaagt gctgggcaaa
    12961 tttgataaaa ctgcggatca ataattgaag attgccgggg atatccaccc ggcaatgtgt
    13021 gaatgcctga tgcgacgctt gccgcgtctt atcaggccta tcttaaccgt tggttaattt
    13081 ttcaaactct tcacacccgg tatcaaaccc ttccatacag ctcaggttca accagtgcag
    13141 cgccttttgc ttgttcttct cgataaaacc ttcttcaccg tttaagaaca tcattcccgc
    13201 ccagtactcg gaataaccgg ttcgggaaat tgcagagctg cgtttgaaat accaggttgc
    13261 cttgtcatcg tcggccttaa tgcccacgcc gttggcgtaa atcaaaccaa gcagcatttg
    13321 ggcatcgacg gcagagtcgt tctccagatc ttccgaggcg ttttctaaca gcgaaattgc
    13381 ctttggataa tccggtttac ccgcttgagt atttaccaga atatgcgcca gcgttacttc
    13441 accttcttta ctgcccgctt gcgccgcttt ctctgcaaga acttttgctt gtggatagtc
    13501 cagactgacc ggattggtga ttttgatctg cgccagcagc gcgcaggcat cagcatcacc
    13561 gctgtcggcg gctttctgtg cccaatattc ggctttgctc aaatcgccgg agctaaacca
    13621 gctgtcggca agaaaatatt gtgcgcgtcg gtccccggcc tctgctgcct ttaaatactg
    13681 gctgccaggc tcggagtcgt tggcgtgggc aaagaatgtc aaaaacaaca tcaatgcgat
    13741 aatttttttc attttgataa tacgattggg tagggagtaa ccagtataaa gagttcgaat
    13801 ggataaaaaa acagcctccg aaaggaggct gtagaaagga cggtattacg ccagtgccgc
    13861 ttcgcgcagg cgagttttca acttgttgta ctcgtcaatc acgtactgct cggcggcgcg
    13921 ctgatcggcg atcggctcga cgcgaacggc gcagtatttg tactccggcg ttttcgtaat
    13981 cgggcttaag ttttcggtaa ccagctcgtt acaggcacca atccaccact ggtaggtcat
    14041 gtaaatcgcc cctttgttcg gacgatcgct gacctgcgca cgggtgataa ttttgccttt
    14101 acgcgagtgc acccaaacca atgcctcatc ttcaataccc agacgtttgg cgtcttcggt
    14161 attgatttgt gcgtagccag gttcatcagc cagcgccgcc agtgccgcac agttaccggt
    14221 catcgaacgg caagagtagt gaccaacttc acgcaccgtt gacagtacca tcgggtactc
    14281 gtcggtgagt ttgtcgattg gcgctaccca gtcgcaggtg aagaactgcg ccagaccgtt
    14341 cggggtatca aacttctctt taaacagata agaagtcccc tgatcggcat ctgaagtatc
    14401 gcggcaaggc cactgaatga agcccagttc gcccattttc tcgtaagtcg caccgtagaa
    14461 atccgggcac agatgacgca actcatccca gatctcctgg gtgttgttgt agtgcatcgg
    14521 ataacccata cgggtggcga tttcactgat gatttgccag tccgttttca gatcccattt
    14581 cggttcaacc gccttgaaga aacgctggaa gccacggtca gccgcagtaa acacgccttc
    14641 atgctcgccc cacgacgttg acggtaaaat aacatccgcc gccgacgcgg ttttggtcat
    14701 aaagatgtcc tgaacgataa ccagttccag atcttcaaag gctttacgta ctgccgacag
    14761 ctccgcgtca gtttgtagcg gatcttcgcc cataatgtac gcggcacgca cttcgccatg
    14821 cgctgcgcgg tgcggcagct cgctgatgcg atagccggta tgcgctggca ggctttccac
    14881 gccccaggct ttggcgaatt tctcgcggtt agccggatct ttcacgtact ggtatcccgg
    14941 atacgtatcc ggcagcgcgc ccatatcgca ggcaccctga acgttgttct gaccacgaac
    15001 cgggttaaca cccgcatgcg gcttaccgag gttaccggtc agcatcgcga ggctggtcag
    15061 agaacgcacg gtttccacgc cctggtagaa ctgggttaca cccatgcccc acaggatggc
    15121 ggcgcttttc gcctgggcat acatccgtgc cgcctgacga atctcactgg cgctgacgcc
    15181 ggtgatatct tcaaccgact ccggcgtgta gccttcaacg attttacgat actcttcaaa
    15241 gccttctgta cgtgaagcga cgaacgcttt gtcgtacaga ttttcttcaa taatgacatg
    15301 gcccatcgca ttcaacagcg cgatgttcga gccgtttttc agtgcaatgt gcatgtcagc
    15361 aatgcgcgcg gtttcaattt tgcgcggatc gcagacgata attttcgccc cgttacgttt
    15421 agcgttaatt acgtgattcg ccacgattgg gtgggaatcc gccgggttgt acccgaaaac
    15481 gaacactaaa tcggtattat caatttcgtt aatagcattg ctcattgcgc cattaccgac
    15541 cgattggtgc agacctgcaa ccgatgggcc gtgtcagaca cgagcgcagc agtcaacgtt
    15601 attggtacca ataacggcgc gcgcaaattt ttgcattaca tagttggttt cgttacccgt
    15661 accacgcgag gagccggtcg tctggatggc atccggaccg tacttctctt tgatggcgct
    15721 caggcgctcg gcaacgtaat tcagtgcctc atcccaggaa acaggttcga gtttgccgcc
    15781 acgctggcga cggatcatgg gggttttcag gcgcggggtc aggatctggg tatcgttaat
    15841 gaagtcccag ccataataac ccttcagaca cagggtaccc tggttggttt tcccctgcgc
    15901 tgcctccgcc cggacgattt tgccgttatc gacgaccagg ttgattttgc aacctgatgc
    15961 gcaatagggg caaaccgtga cgactttttt catcggtctc gctccagtta atcaaatcac
    16021 gcatacgcgc tctcgactac agtatgcatc ttttatgcca cattttatgt ggggtcattc
    16081 cctgatatta cgggcactat ttattcaaaa ctctgacgaa aaacaggctg tcgtcagttt
    16141 tgacgtgacg aaacgaaata ccgcgtgaca gccatcacgc ggcagacatt ttattttttc
    16201 tcgacgacgg gacctgcctg atacccgccg cccagcgatt tcatcaactg aatgctttgg
    16261 atcacccggc ggctgtccag catcagtaat gacatctctt cggcaagcac tggcaaccgg
    16321 gcttcggtgg cctgtaagcg gctggttaag ccgcgctgat aggcggcctc ggcagcgcgc
    16381 tgggtaaagc gcgtggcttc cacgcgttca gcctgcattt ctcgctcgtc gttgagcgtt
    16441 tgcagacgcg tgccgttgac ggcaacgtca cgcaccgcgt tcagtactga ctggttgtaa
    16501 cgttcaatca tcatgttgct ggcggcgcgc gtgccttcga gattggcatt caaccgtcca
    16561 ccgtcaaaca gcggcaattt cagacccggg atgaagttga actggcgact ggtttttttg
    16621 aataaggtat gcagatggat ggagtccaga ccgaaaaacg ctttgatatc aaagctcgga
    16681 tagaacaacg cccgcgcgga atccacctga tctaatgacg cctgaacata ccagcgcatg
    16741 gcttgcagat ccgggcgtct ggcgagcaac tcataagaga gtgtcgccgg aatgccggtc
    16801 tggacttgcg gtaatgccac cggtctgatc tccggcatat cgctggctcc cgcgccaatc
    16861 aatgcacgca gagattctcg cgtttcggtg atttgccctt tgacggcaac aatttgttta
    16921 tcgaccgcca gaatctgtgc ccgcgcgccg tggaaaggca cttgcgcttc cagaccgtgc
    16981 gccactttac tctggtgcgc tttcaccgcg taatcaatca catcgtgagt ttgttctaac
    17041 agatcgagca tctgatagct ggcctgcata ctgtaataaa gctgcgctac gcccgtggcc
    17101 agcgatagct ctactgctgc ggtttctgcc agcgcggcat tatgcgcgcc aatggcggcg
    17161 gcaaccgctg agcgatgcac accccacaaa tcaagatcca gtccggcaaa caaacctact
    17221 gtggcttccg tatagtacgg cccgtccata cccagtgctg gcgcatccat tgaataaggg
    17281 cttaaaaagc cgttcgccga gacacgttgg cggttgagca tccctaacgc tgcgacctgt
    17341 aattgtgaac cggcatctaa caaatcggcc tgggactgcg ctttttcttc ccgcagtttc
    17401 gcttcggcga gggtgtgtga accacttagc gtccgttgga tcagcgcatc cagctgcggg
    17461 tcattgagtt gtttccacca ctgcgcctgc ggccagccgg agctggcaag atgaatatcg
    17521 tcggccagtt tgatttgttc cggtttgagc tgttgatgag gtgcagaatc cttacgtacc
    17581 agggcacagc cggaaatcag cgtcgtgctg ccgagaatgc tgcacaacag cagacgtgaa
    17641 agttgacgat tgatcattgc gtggctcctt gtgcctgttc cgtggcgggc gttaatgccg
    17701 gggctgtcca gtctggcaag cgggcgaaaa gctggcagac gtgttgctcc tgttttaata
    17761 aggtgggcag gatggcctga gaggcgggtg tctcttcaag cgttatttga ggagaacggc
    17821 tgagtgcggt tgccagaccg gcagcgtatt tctccagggc gtcggcaaac tgacctgctc
    17881 tgtccggctg tagtgcgtta tccagcgcct gcgccgagtt ccaggtggca tcccaggcgt
    17941 gaagaagatc gcggccctga cgaataaccg tttgcgaacg ttcaatcagt aatgcgcgtt
    18001 cttcgctgtc cagttgacgc tccagcgcca cgcgttggca catctcttca caggcattaa
    18061 acgccgcatg cagaccgata cgaatttgca gataagtgcg cagagccgtg acttcctgct
    18121 ggcgtgggat ccgcattact ttacttaaca tacccagcgt gccagccagt ttttgcggca
    18181 gtgtgcgcgc ttcactttca ggccagacaa aggtgtaaat caccgcggac accacggtac
    18241 caatgatgat acccagggcg cgatcgcgaa tttccaccag gtcgtacact gggccaaaaa
    18301 cgttttcgag cgtggcgagc gcgaaggtga ccaccatctg tgtgccgata taagaagagc
    18361 gttcagagct ggtggcaatc catgcgccca acaggaaaat cggtgccagc acaaacagca
    18421 attcgacaat attgtccagc cagggcatga ccagtagcgt gaataacagc gccagaatcg
    18481 cgccgcaaaa ggccccgcca aaacgcagca ccatcttctg gtacgacgaa ccgacatttg
    18541 ggttagcgac gatcacgcat gtcagcatac aggtgtgaat gccttcccag tccacgccgc
    18601 tgtaaaaggt gtaacagatc aaacaggcga gcagcgtttt taccgcgtag cgcatatagt
    18661 ctggattggt aaaagcatcg gcggccattg atggcggttt ggctgcgggc gttggcggcg
    18721 tattcgggtc catctgaccc agttgtaaca acgtctggca gatattctcc aggttacatt
    18781 cccgtgccgc catcgcttca ctttcactga tccgccagtc gctttgccag cactgacctt
    18841 cagcaacggc atgctgcagc ttgttgattt ctgaagctaa tttttgtcgg aattcaataa
    18901 ttgcctgaga atcagcaaaa gaggtgggat cgtagcgatt cagcgtcgag taaatgtagg
    18961 ttaccgttgc cacgcagctt tgccaccatg cgttttgagt tcgccagttg gcatcgtccg
    19021 cgaggcaaaa gacattgagt ttttgtagcg ccagcgcctc tctttcaatc cgcgtttcgg
    19081 gtagcggtac gaggctgtct gtcaggtgac taatggcatc atcaagccga tcattaagcg
    19141 cctgatgcat ttgcgaaatg gcacgactgg gaaaccacag cacgccgatt aacgtcatca
    19201 gcaaggttgg atagaggcca acaacgatac accacagcgt taagcgcacg accacttccg
    19261 gatagtcgag catggcgggg aaggtttgcc cgtaaatagc gacaatggcg acggcgaaaa
    19321 agaccagccc caagcgatgg gtgcgcatca aaaacatgca gcccatcagg atcggtccgg
    19381 cgatgatcaa tcggatcaac ggttcgccgt atgaccattt gtagatcaaa aacaggctgc
    19441 cgatctccag caccgtggca accacaaaca agatcgcgac aaatttggtg taaaacgcgt
    19501 tcgactgaat accgtaaaac agcactgcca gcgataacgc cacaaaaggg atctcaaagg
    19561 tcatcgagat cagaatcacc agcaggcagc ctacccagag ttgcacggtc tgcggcacgc
    19621 gacctggtcg ccgctcgctt aactcttcat gaaagaacgc cagcagcctg accaccggta
    19681 atggcaggga gttgagcgcg ctcattattg cggctcaaga ttagcgactg ccgaagcgcc
    19741 gatgcggaac atttccgggt caggtttatc gaccatgatt ttgaccggaa aacgctgggc
    19801 aacgcggacc cagttaatag aacgagacac tttcggcagg ccgcccagca ccaggccgcc
    19861 gtcatccggt agcacgccgt agccaatcga atccacttta ccctcgaagg ttttgccgct
    19921 gtcactcatc aggcgaatcg ttgcgggtgt acctgagcga atatttttca gatcggtttc
    19981 gcggaagttg gcgatcacat accagtgacg agtgtcgatt agggtaaaaa tagggcgcat
    20041 ggcagaagca aattgcccga cggaggtttt gagggaaatg acccggccat caaacggcgc
    20101 gcgaacggtc gccatttcca gatgcagttt ggtcagggca atatccgctt cgaccgccgc
    20161 acgctgggca actaatgcat ccacgccgct gacggcgctg gcggctgact gcgcctgtaa
    20221 caatacggca ttaagatccg cttctgcggc gcgctgcgcc gttcttgcac ggtcaacatc
    20281 ttccgctgag acaaaacctt ctttcagtaa tggctcggtg cggcgtaatg tatctgtggc
    20341 ctgtttcgcg gcggcacggg ctttttctac cgtggcatta accgagtcgg caccaaactg
    20401 ttgcgcgtca acgctacgct gggtgagcat aatttgctta tccagcgccg cgagggaggc
    20461 ttcagctttc gccagattgg cttcgtacgg gcgcgggtcg atgcggaaca gcaaatcgcc
    20521 ctgtttgact gcctggttgt cggtgaccgc cagttctaca atgcggccgc tgacttccgg
    20581 taccacatca atggtatctg ctgacgcgta agcgtcatta gttgatggcg cactgtctac
    20641 gcgccagata acgaaaacaa gggcaaccag cgccaacgca accactaaca gagcagggaa
    20701 tttactgcga ggagcttttt tcggcgtact ttccatgagc gcgtctcaaa tagattagaa
    20761 aaatgccagc cagaacagca tggcgtagag agcaaaaagg gcggtataaa taattccgac
    20821 aaatgccaga ttgatatttg cccgctgaat aactcgcctc gtgatgagcg tcaaaataag
    20881 gctggcaatg gcgcagaaaa accagctggg ataataagcg ccgatcaccg ggattgccgg
    20941 agataatgag catcccgaaa ccatgaagac gggaattatc caggctgttt ttttgagttg
    21001 catcgccatg cgagagagaa ctgttggcat attaaataca tcctgtctgc tgcgaacaat
    21061 atctgtagtg aatatcaata tccattgaag gcgtcagtat ggctattttc ttgatgaata
    21121 aaaatagctt tattcagcca ccgcattcat aacttatata ttttatttat taattggctg
    21181 tatatatttt taaaataaat acttttgggg gcttcagcgc ccccaaaagc gagtgacatt
    21241 aatttggggt tacgatattc acccacaaat cgaaattatc cagacaggcg ataatttctt
    21301 ccagtttcgc gccattgcca ataattttgg ctttcttcgc ttttaccaga tccgccattt
    21361 tggcttgtcc ggtcagcacg gcgtgcagat cttcacggct gatgtagaaa gaggcgtcgg
    21421 cttgcggttg cagcgttttc cggtagttaa gcacgctatc gttcagcgtc aggttgaggt
    21481 tatcgccgtt gctcatattg aagttcaggc tgatattttt acccgcagct ttcgcgctat
    21541 cgaggcgaac ggccataaag tcgaacagca tttcgaccga catcccgcga atggtgtccg
    21601 gggaaccggt ggtgccgtgg ctgaacttat gcaccccttc gcgcagctct ttcgcgccgg
    21661 tcaggtagaa accgcgccat gtggcggact cggcctgata gcccagctgt tcaaagttat
    21721 tcgcttgcag attcttcgcg acctggtcac ccgggttggc ggcaatcacc tgtttcagca
    21781 gttctgccga ccagcggtaa tcaccttgct tgttcgcttc ttgcgccagg ttgatgacac
    21841 gggcagaacc gcccagcgcc tgcacgtaac gtttacccat ctccacctga ccatacggat
    21901 gcaggttagc cgggttaccg tcgtaatagc caagatagaa gttatacacc gcgcgggcgt
    21961 tgtggctgac agaaccgtaa tagccgcggc tggcccagtt attggcaagt gcaggcggca
    22021 gcttaatcat gtcgccgatt tcattcatgg tgtagccctg gttcgccagg tgcagggtct
    22081 ggtcgtgaat gtacttgatg gtatcgcggt atttaccaat ataatcattg atatgcttat
    22141 tgccccagac cggccaggtg tgcggcataa acagcacttc cgcgtcgtta ccccacatat
    22201 ccagcgtttc gttcagatac tcggtccact tgctggtgtc gcgggttttc gcgccgcgca
    22261 gagtgtagaa gttgtgcagg gtatgcgtgg cgttctcggc ggtacacagg gctttcaggg
    22321 ccggaatata gaagtgcatt tcggctggcg cttcgctacc tggggtcatc aggaagtcaa
    22381 actccaggcc gtcgataatc atcttctcgc cagttctgac gatagttttc gtcggtgcaa
    22441 taatgctcgg gtcgcccgtt gccagcgtca cgccaaggcc attacccaca ttgccttgcg
    22501 cgttgtgcgg cagtaacaga ccgtaagagt agagcgcacg gcggctcatg atgttacccg
    22561 ccagcacgtt ttcgctgatg gcttcgtcca taaagcctgc aggggcaatc acctgaactt
    22621 tgccggattt aacatcggct tcagagataa tgcctttcac gccaccatag tggtcggtgt
    22681 ggctgtgagt gtagataacg gcaacaatcg gtttttgcgg acgatgctgg aagtaaaggt
    22741 caagtgcggc ttttgcggca ggcggcgtca ccagcgggtc gataacaata atgcctttct
    22801 cgccctcaac gaacgtaatg ttagagatat cctggccgcg cacctgatac attttatcgg
    22861 tgactttgaa caggccagaa ataccgttga tttgcgactg acgccacagg ctggggttta
    22921 cggtttccgg cgctgcggca ttaatatcaa atttgtaatc gtccgcgcgg tagtaaactt
    22981 taccgttcgc atcacgcaga ataccttcat ccagcagcgg ggcgataaat ccacgctggg
    23041 catcgtcaaa atcctgacga tcgctaaacg gtaatgattt ggcgtaattc tgattaacct
    23101 gttgggtata ttgagtggcg gctttcgctt cctctttcgc gttagcggta tttaccatca
    23161 tgccgctggc ggcagttaac gcaataacaa tcctgctcaa acggaataac cgagagttat
    23221 tcatataaat ctccatttat catttatgtc gtaaatatgt aatccatgca aaatacgtca
    23281 tttaaagctg gcgttatcat aattgggaaa ttgcgacttt aataagtgga agtgtgagcg
    23341 gaacgcgcca ttttattagg catttgtgct gaagagggaa aattacagta aaactatcat
    23401 tgcagaaaat aatatgagtc gttttatgtg tttattatat atattgtacc tgtcgttggc
    23461 acagcgggac attgcgctac tgtgccaacg ttttactcat ggggctttag cacagaactg
    23521 tggcaaaaaa cgttgatgcg ccaatattgc tgcaccctga gcgccattaa agtcagaaga
    23581 tgaggcggca ataaagcgca cgacctgatg cggcagtgga cggcgcaggt acttttgggt
    23641 catggcaacg agagtctcgc gtgggaaggc gggcatatcc atcacgccac cgcccaggat
    23701 caccgcatcg ggatcgaaca gattaatgct ggtggcaatg gcccgtgccg cgttttcaag
    23761 cagactctgg acgaaagggg cgttttccgc atggacgaaa agatcgcgca atgggtaatt
    23821 tcggggctgt tgttcgtacc agcgtcttag cgccattcca gagcaattgg tttccaggca
    23881 cccaggattg ccacacgcgc agtgttgggt catatctccc agggggatat gacccagttc
    23941 gcctgccaca ccgtgtgcac ccgtccacgg cgcaccgttc atccacactg cgaaccccat
    24001 ccccgtaccg agataggccg ccagaaccag ttgttgcgta aggcggtttt ctactacgtc
    24061 ccaggagagt tgcaggttaa cgtcgcggga aaactcaacc ggacaattca gcgtattttc
    24121 gagcttatcg gcgagatcat ataaatccgc cgctgttaac ggcaggttag gcgtagaaat
    24181 aatggtgcgt ttatctttac tgaccagcgc cggaaatccc atcaccagac catgacagcg
    24241 agcgttaaag cgcctgagtt gctcgtcaat catttcgccg atacccgaca ccaggccggg
    24301 agcaatgact tctgcggtcc gctttttttc gcagtgtagc gtttcacctt ctgctgtccg
    24361 cagacaaaag cggatatgcg ttgcccccat atccacgccc gctacgacgt tatgctgttt
    24421 ttgcatgagg ctgtacctcg ctttttgcag ccagaatctg cgcggtcata attctccatg
    24481 cttcgtcgat attttccgca tgattaaaca ggccggaagt gccgacgata aagacatccg
    24541 cccctgccgc catcagtttt tcgtaagttg cctggttgca ggaaccgtcc acctcaattt
    24601 cgtactccag accttctcgt tcacgccatg ccttcagttc ggcaagttta tccagcattt
    24661 caggaatgaa cggttgtccg gcaaagccgg gatcgacagt catgaccgta attttatcgg
    24721 ccttatggat atagtatttc atggcctcaa ctggcgtctc cgggttaagg atcagcccca
    24781 ctttcatgtc atgacggcgg atttcatcaa tcaggcggaa cgcctggccg ttgatggttt
    24841 ccggatgcag agtgatgaaa tctgctcccg cacgcgccag ttgagcaatg taatcctgcg
    24901 gccgcgtcac catcagatga cagtcgagcg gtttagttgc cagtttttta acctgactta
    24961 cgaagaacgg tgagagtgtc agattgggga caaagtgacc gtccatgata tcgatgtgga
    25021 agtaatcggc atggctgtcg ataaattcga tctgttcttt aaatttcagc agatccatac
    25081 acattaacga gggggagatt ttcatgttca attccttact tactgataag acggtcaagg
    25141 gcgacagccg cgataattaa tccgcccatc accaccagtt ggtaataggt ttgtacctgc
    25201 aaaatattca gaccgttgtt gatggtgccg atgatcaacc cgccaatcac cacagagaaa
    25261 atgcgcccct tgccgccgaa gaaactggtg ccgccaatga tggcgctggc aatggcatag
    25321 gtttcaaaac ccataccggc aagcggttct gcggcaccga gtcgtgcagt tgagacgacg
    25381 cctgccagac ctgcacaaac accggagatg ataaacacca ccaggatgtg gaatttcacg
    25441 tcaatcccgg aatagaacgc cgaatttttg ttgccgccca gtgcgtagat gttgcgcccg
    25501 agccgcatac gcgttgtcag aaaccaaagg atgagcgcga caattagtga gaagataacg
    25561 gggacaggta tcccaattac gctggcggca aagaagttca cgaagtcaaa tgagaagccg
    25621 tataccgagt tggcatcgga gatcaccagc gtgatcccac ggaaaatcgc gttggtgcca
    25681 agggtgatga tgaacgggtg tagccccgtc cagttgacca ggcagccgtt gatcgccccc
    25741 agtgcgccgc caaccagtac accgccaatc atcgctgcga gaaacgggtc aacacctgcc
    25801 aacatcagtt tggcggtcac cataccggaa agcgccagaa tcgcgccaac cgagaggtcg
    25861 ataccagcga ccaggatagc gaaaaactcg cccatgccga tcaataccgt cacggagctt
    25921 tgaacaaaaa tctgggtaat attattggtg gtcagaaaat attctggtga cagcgaacca
    25981 aagatggcga cgatgatcgc caggataaaa aaggtgccgt atttatccca gaacagcgca
    26041 aagttgaacg gtttcttctc gctcgcttcg ctttttactc ttgtggtaaa gcccatgcca
    26101 taatctcctc ttcgctcatg tcatcgcgat tcgtcaggat ttgcgtcagt cgtccttcgc
    26161 agaacacggc gatgcggtcg cagacggtga taatttcagg tagttcagat gacaccatca
    26221 ggatgacttt tccgtcgtcc gccagttggc gcatcacttt gtaaatttcg gctttcgcgc
    26281 caacgtcgat gccgcgggta ggttcatcga aaataatcac ttccgggcaa cagcacagcc
    26341 atttggagat caggactttc tgctgatttc ccccggagag ttcggtgata ttctggttta
    26401 ccgaatgaca tttcagcgcc agcagttcgc gttgattttc agcggtacgt tgctcgtcaa
    26461 cttcatgaaa caagcccatc gcgcctttat agccgccgtc tttcagactg cggctgatcg
    26521 ccatgttctg agcgattgaa aagttgggga aaaaaccgtt atcccggcgg ctttcagtga
    26581 tgtaagccat cccttttttc acggcatcca ggggtgaacg tggagagata tctttgccat
    26641 taagacggat ttctccgcca gcgcgtttat ccacgccaaa cagacaattc atcagttcag
    26701 tacgtccgga accgaccagt ccggcaaagc ctaatatttc tccccggcag acgctaaatg
    26761 agatatcccg gacctttttt ctgtcacgac tggtgacgtt ccgcacctca aaaaccgttt
    26821 cgtgcgcaag gttgctgaca ttctccttca tcgcgttaaa acggttttgc agttcgcggc
    26881 ctaccatcag acggacgata tcgtcatttg acacatcgct tactatgccg ctgcaaacgc
    26941 tgctgccgtc tttcatcacc gtatagcggt cgcaaatacg gcgaatttcc gccaacttat
    27001 gcgagatata gacgatggcc gtaccctctt tacgcaactg attcatgatc agaaacagat
    27061 agtccacctc tttattggtg agtgaggagg tgggttcatc catgatgatg actttggcat
    27121 cgagcatcag cgttttggca atttctagca tctgcttgtg gctgatagat aaattcgcca
    27181 ctttctcatc tagatcaact ttcaagccca cgcgtaataa catcatggcg gcgcggacac
    27241 gcatttctcg ccagtcgata atattgacgc cacagatttt tttcgtcaga tgacgaccaa
    27301 tatataaatt ttccagtacg gttaattcat caataacgct gagttcctga taaataatcc
    27361 cgataccgag ttgtgccgct aatttatgat ccagcttgtt atagctaatg ttattaatgg
    27421 taatggtgcc tttggtcggc tcatgtattc cggataaaac tttcattagc gtggatttac
    27481 ccgcgccatt ttctcctagt aatgcatgta tttcaccagg ataaaccgtt aaattaaccg
    27541 actttaatgc gtgaaccgga ccaaaggact tgccgatccc cgccatcgat atatatggcg
    27601 tggccataaa taacctctct gcacgaaata tcgtattatt gcctgatggc tacatttatc
    27661 aggtctacgt tcaggttatt ttgttggccg gataagacac ttcattagca tcatcatccg
    27721 gcatcattca gttttattga gtgaccagga ttgaatcgac cagtttaaat tccggtgctt
    27781 tatccagcgg gataaccttg ccggatttct cagcgtcaac catcagcttc agacccgttg
    27841 cgccgatatc cgccgggttc tgggcaaccg tcgcggtcat ttgtccggct tccaccattt
    27901 tgcgggcttc cggaatgcca tctgtaccga cgaccagcac ttttcccgtt tttccggcgt
    27961 ttgcgactgc ctgagcaaca cccattgcca tcgtgtcatt cgcgcaatag atcgctttaa
    28021 tattcggatt acgttgcaac acgttagtgg cgacatccag tgctttaatg cggtcccagt
    28081 cggcaggctg gctggcgaca agcttgatct ggcttgcttt tttgaaggct tcggtggcac
    28141 cattacgacg cgcttcaccg gaggcgttac cggctttacc ctcaatgatt gcgacttcac
    28201 caccttcagc gcccaatttg tcaataatga acgacgcgcc tttcgccccg acagcaacgt
    28261 tatcggtggt gacaaaagct tccacattgc cgccagcttt tttcagatta tccatgtcga
    28321 ttttttcatc gagattaacc agataaatgc cttttttcca tgcgcgggcg acaggcatga
    28381 ccagattcac tgaggataat ggagcgaagg cgataccttt gtaattttta ttactgagat
    28441 cttcaaataa ctgcaattga gattgaaaat cgccttctga aggagaggca aaaatatcaa
    28501 cgctgacgcc cagtgttttt gcttcatctt caatgccttt tttcatatct acccaaaatg
    28561 ggttggagag ggttttcaat acgacagcat attcggcggc agcaaaagcg ctggt
//
LOCUS       DACAOP010000055        28040 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.055, whole genome shotgun sequence.
ACCESSION   DACAOP010000055 DACAOP010000000
VERSION     DACAOP010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28040
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.055"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(172..921)
                     /gene="chbG"
                     /locus_tag="IT892_002680"
     CDS             complement(172..921)
                     /gene="chbG"
                     /locus_tag="IT892_002680"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HAP3135883.1"
                     /translation="MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAID
                     HAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQ
                     ELVSQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEQGIALRADRQMAFDLP
                     VNLRTTQGFSSAFYGEEISESLFLQVLDDAGHRGDRSLEVMCHPAFIDNTIRQSAYCF
                     PRLTELDVLTSASLKGAIAQRGYRLGSYRDV"
     gene            complement(934..2286)
                     /locus_tag="IT892_002681"
     CDS             complement(934..2286)
                     /locus_tag="IT892_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP3135884.1"
                     /translation="MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEGG
                     KPKLDIIFDLCQRMIDNAGVPMKLYKTLDRREALKDADFVTTQLRVGQLPARELDERI
                     PLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVY
                     RHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLVNGKSRF
                     AELLDGVASGQLKASSVKNIFDLPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEY
                     YKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDAACEVINAIYNDKQA
                     EHYVNIPHHGQIDNIPADWAVEMTCKLGRDGATPHPRITHFDDKVMGLIHTIKGFEIA
                     ASNAALSGEFNDVLLALNLSPLVHSDRDAELLAREMILAHEKWLPNFADCIAELKKAH
                     "
     gene            complement(2391..3230)
                     /gene="chbR"
                     /locus_tag="IT892_002682"
     CDS             complement(2391..3230)
                     /gene="chbR"
                     /locus_tag="IT892_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310468.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ChbR"
                     /protein_id="HAP3135885.1"
                     /translation="MQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDYY
                     EFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFEQ
                     HYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRHY
                     REEQVIDDVPQWLKSTVEKMHDKEQFSESALENMVALSAKSQEYLTRATQRYYGKTPM
                     QIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLTE
                     FNQ"
     gene            complement(3241..3591)
                     /gene="chbA"
                     /locus_tag="IT892_002683"
     CDS             complement(3241..3591)
                     /gene="chbA"
                     /locus_tag="IT892_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIA"
                     /protein_id="HAP3135886.1"
                     /translation="MMDLDNNPDTQTEAEELEEVVMGLIINSGQARSLAYAALKQAKQ
                     GDFAAAKAMMDQSRMALNEAHLVQTKLIEGDAGEGKMKVSLVLVHAQDHLMTSMLARE
                     LITELIELHEKLKA"
     gene            complement(3642..5000)
                     /gene="chbC"
                     /locus_tag="IT892_002684"
     CDS             complement(3642..5000)
                     /gene="chbC"
                     /locus_tag="IT892_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIC"
                     /protein_id="HAP3135887.1"
                     /translation="MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAM
                     FVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFI
                     GMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
                     EMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQII
                     MDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGALALTALDNGIMTPWALENIATYQQ
                     YGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIASRRADYRQVAKLAL
                     PSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTM
                     PTGLGAFFNTNGSVAALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANAL
                     KF"
     gene            complement(5085..5405)
                     /gene="chbB"
                     /locus_tag="IT892_002685"
     CDS             complement(5085..5405)
                     /gene="chbB"
                     /locus_tag="IT892_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIB"
                     /protein_id="HAP3135888.1"
                     /translation="MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLA
                     GEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKK
                     AAAN"
     gene            complement(5704..6042)
                     /gene="osmE"
                     /locus_tag="IT892_002686"
     CDS             complement(5704..6042)
                     /gene="osmE"
                     /locus_tag="IT892_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmE"
                     /protein_id="HAP3135889.1"
                     /translation="MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMS
                     RAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCA
                     EYDTDPQAAK"
     gene            6244..7071
                     /gene="nadE"
                     /locus_tag="IT892_002687"
     CDS             6244..7071
                     /gene="nadE"
                     /locus_tag="IT892_002687"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAP3135890.1"
                     /translation="MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLV
                     LGISGGQDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQ
                     PDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGT
                     DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALACPEHLYKKAPTADLEDDR
                     PSLPDEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK"
     gene            7301..8188
                     /gene="cho"
                     /locus_tag="IT892_002688"
     CDS             7301..8188
                     /gene="cho"
                     /locus_tag="IT892_002688"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease Cho"
                     /protein_id="HAP3135891.1"
                     /translation="MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGES
                     DTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQ
                     QPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQTIA
                     DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCW
                     PWQGAVALKEQHPEMTQYHIIQNWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPL
                     LSGNYEITELDPANDQRAS"
     gene            complement(8148..8723)
                     /gene="ves"
                     /locus_tag="IT892_002689"
     CDS             complement(8148..8723)
                     /gene="ves"
                     /locus_tag="IT892_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="environmental stress-induced protein Ves"
                     /protein_id="HAP3135892.1"
                     /translation="MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIA
                     ANGEFSLFPGMERIVTLLEGGEMLLESADRFNHTLKPFQPFAFAADQVVKAKLTAGQM
                     SMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFD
                     GRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ"
     gene            complement(8926..9411)
                     /gene="spy"
                     /locus_tag="IT892_002690"
     CDS             complement(8926..9411)
                     /gene="spy"
                     /locus_tag="IT892_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-independent periplasmic protein-refolding
                     chaperone"
                     /protein_id="HAP3135893.1"
                     /translation="MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKF
                     GPHQDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKVKAE
                     AQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATA
                     E"
     gene            complement(9741..10709)
                     /gene="astE"
                     /locus_tag="IT892_002691"
     CDS             complement(9741..10709)
                     /gene="astE"
                     /locus_tag="IT892_002691"
                     /EC_number="3.5.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate desuccinylase"
                     /protein_id="HAP3135894.1"
                     /translation="MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQG
                     ALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDM
                     NRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPQFGV
                     LPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFG
                     QNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFM
                     PFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS"
     gene            complement(10702..12045)
                     /gene="astB"
                     /locus_tag="IT892_002692"
     CDS             complement(10702..12045)
                     /gene="astB"
                     /locus_tag="IT892_002692"
                     /EC_number="3.5.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-succinylarginine dihydrolase"
                     /protein_id="HAP3135895.1"
                     /translation="MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQ
                     GLLKMKALADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSS
                     ASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFS
                     VHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREAS
                     EAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLAN
                     LRARVNGFMAIEVPATQVSVSDTVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGY
                     LNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFN
                     ALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG"
     gene            complement(12042..13520)
                     /gene="astD"
                     /locus_tag="IT892_002693"
     CDS             complement(12042..13520)
                     /gene="astD"
                     /locus_tag="IT892_002693"
                     /EC_number="1.2.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate-semialdehyde dehydrogenase"
                     /protein_id="HAP3135896.1"
                     /translation="MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVEQACR
                     AARAAFPRWARLSFAERHAVVERFAALLESNKAELTAIIARETGKPRWEAATEVTAMI
                     NKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
                     AGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLF
                     TGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQR
                     CTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAW
                     QQLEAMGGRPLLAPRLLQAGTSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDTFDEA
                     IRMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGN
                     HRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR"
     gene            complement(13517..14551)
                     /gene="astA"
                     /locus_tag="IT892_002694"
     CDS             complement(13517..14551)
                     /gene="astA"
                     /locus_tag="IT892_002694"
                     /EC_number="2.3.1.109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine N-succinyltransferase"
                     /protein_id="HAP3135897.1"
                     /translation="MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSARIERAI
                     KTWQGELPKSEQGYVFVLEDSETGTVAGICAIEVAVGLNDPWYNYRVGTLVHASKELN
                     VYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVV
                     AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLS
                     QEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVE
                     VAEGQPAQGDFPACLVANENYHHFRVVLVRTDPATERLILTAAQLDALKCHAGDRVRL
                     VRLCAEEKTA"
     gene            complement(14548..15768)
                     /gene="astC"
                     /locus_tag="IT892_002695"
     CDS             complement(14548..15768)
                     /gene="astC"
                     /locus_tag="IT892_002695"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.81"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylornithine/acetylornithine transaminase"
                     /protein_id="HAP3135898.1"
                     /translation="MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDF
                     AGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFC
                     NSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAP
                     LPADIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNA
                     LLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECARVMTVG
                     THGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLNTINHRYGLFSEVRG
                     LGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDR
                     FAAACEHFVSRGSS"
     gene            16214..17020
                     /gene="xthA"
                     /locus_tag="IT892_002696"
     CDS             16214..17020
                     /gene="xthA"
                     /locus_tag="IT892_002696"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAP3135899.1"
                     /translation="MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDDMFPL
                     EEVAKLGYNVFYHGQKGHYGVALLTKETPIAVRRGFPGDDEEAQRRIIMAEIPSLLGN
                     VTVINGYFPQGESRDHPIKFPAKAQFYQNLQNYLETELKRDNPVLIMGDMNISPTDLD
                     IGIGEENRKRWLRTGKCSFLPEEREWMDRLMSWGLVDTFRHANPQTADRFSWFDYRSK
                     GFDDNRGLRIDLLLASQPLAECCVETGIDYEIRSMEKPSDHAPVWATFRR"
     gene            17187..17897
                     /locus_tag="IT892_002697"
     CDS             17187..17897
                     /locus_tag="IT892_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416264.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family membrane protein YdjX"
                     /protein_id="HAP3135900.1"
                     /translation="MNAERKFLFACLIFALVIYAIHAFGLFDLLTDLPHLQTLIRQSG
                     FFGYSLYILLFIIATLLLLPGSILVIAGGIVFGPLLGTLLSLIAATLASSCSFLLARW
                     LGRDLLLKYVGHSNTFQAIEKGIARNGIDFLILTRLIPLFPYNIQNYAYGLTTIAFWP
                     YTLISALTTLPGIVIYTVMASDLANEGITLRFILQLCLAGLALFILVQLAKLYARHKH
                     VDLSASRRSPLTHPKNEG"
     gene            17902..18579
                     /gene="ydjY"
                     /locus_tag="IT892_002698"
     CDS             17902..18579
                     /gene="ydjY"
                     /locus_tag="IT892_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416265.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdjY"
                     /protein_id="HAP3135901.1"
                     /translation="MLQHYSVSWKKGLAALCLLAVAGLSGCDQQENAAAKVEYDGLSN
                     SQPLRVDANNHTVTMLVQINGRFLTDDTRHGIVFKDGSNGHKSLFMGYATPKAFYEAL
                     KEAGGTPGENMTMDNKETTHVTGSKLDISVNWQGAAKAYSFDEVIVDSNGKKLDMRFG
                     GNLTAAEEKKTGCLVCLDSCPVGIVSNATYTYGAVEKRGEVKFKGNASVLPADNTLAT
                     VTFKIAE"
     gene            18594..19301
                     /locus_tag="IT892_002699"
     CDS             18594..19301
                     /locus_tag="IT892_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP3135902.1"
                     /translation="MMMMQSRKIWYYRITLIILLFAMLLAWALLPGVHEFINRSVAAF
                     AAVDQQGIERFIQSYGALAAVVSFLLMILQAIAAPLPAFLITFANASLFGAFWGGLLS
                     WTSSMAGAALCFFIARVMGREVVEKLTGKTVLDSMDGFFTRYGKHTILVCRLLPFVPF
                     DPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSMLTGGTFWFVTGLFILFALTV
                     VIFMAKKIWLERQKRNA"
     gene            19301..19849
                     /locus_tag="IT892_002700"
     CDS             19301..19849
                     /locus_tag="IT892_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAP3135903.1"
                     /translation="MGLPPLSKIPLILRPQAWLHRRHYGEVLSPIRWWGRIPFIFYLV
                     SMFVGWLERKRSPLDPVVRSLVSARIAQMCLCEFCVDITSMKVAERTGSSDKLLAVAD
                     WRQSPLFSDEERLALEYAEAASVTPPTVDDALRTRLAAHFDAQALTELTALIGLQNLS
                     ARFNSAMDIPAQGLCRIPEKRS"
     gene            19859..21025
                     /locus_tag="IT892_002701"
     CDS             19859..21025
                     /locus_tag="IT892_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP3135904.1"
                     /translation="MRHCGWLLGLLSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDT
                     AINRYLDWVSGEMKTHYAINLKIVRLADAADAVKRIQTEAAAGRKTGGSVDLLWVNGE
                     NFRTLKEANLLQTGWAETLPNWRYVDTQLPVREDFSVPTQGAESPWGGAQLTFIARRD
                     VTPQPPQTPQALLEFAKANPGTVTYPRPPDFTGTAFLEQLLIMLTPDPAALKEAPDDA
                     TFARVTAPLWQYLDVLHPYLWREGKDFPPSPARMDALLKAGTLRLSLTFNPAHAQQKI
                     ASGDLPASSYSFGFREGMIGNVHFVTIPANANASAAAKVVANFLLSPDAQLRKADPAV
                     WGDPSVLDPQKLPDGQRESLQSRMPQDLPPVLAEPHAGWVNALEQEWLHRYGTH"
     gene            20998..22533
                     /locus_tag="IT892_002702"
     CDS             20998..22533
                     /locus_tag="IT892_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416269.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP3135905.1"
                     /translation="MATPLRYALIFLLWAMVAVIYAPLIPAALTLISPALSLTHWQAL
                     FADPQLPQALLATLVSTTIAAVGALLIALLVIVALWPGPKWQRMCARLPWLLAIPHVA
                     FATSALLLFADGGLLYDYFPYFTPPMDRFGIGLGLTLAVKESAFLLWILAAVLSEKWL
                     LQQVIVLDSLGYSRWQCLNWLLLPSVAPALAMAMLAIVAWSLSVVDVAIILGPGNPPT
                     LAVISWQWLTQGDIDQQTKGALASLLLMLLLAAYVLLSYLLWRSWRRTIPRVDGVRKP
                     ATPLLPGNTLAIFLPLTGVLCVVLLAILADQSTINSEALINSLTMGLVATFIALLLLL
                     LWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLKLDGSWTAVVWGHLLWVMPWML
                     FILQPAWQRIDSRLILIAQTLGWSRAKIFFYVKCPLMLRPVLIAFAVGFAVGIAQYMP
                     TLWLGAGRFPTLTTEAVALSSGGSNGILAAQALWQLLLPLIIFALTALVAKWVGYVRQ
                     GLR"
     gene            22533..23186
                     /locus_tag="IT892_002703"
     CDS             22533..23186
                     /locus_tag="IT892_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP3135906.1"
                     /translation="MLCVKNVSLRLPESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLF
                     SWMIGALAEQFSCTGELWLNEQRIDILPTAQRQIGILFQDALLFDQFSVGQNLLLALP
                     ATLKGNARRNAVNDALERSGLEGAFHQDPATLSGGQRARVALLRALLAQPKALLLDEP
                     FSRLDVALRDNFRQWVFSEVRALAIPVVQVTHDLQDVPADSSVLDMAQWSENYNKLR"
     gene            23253..24560
                     /locus_tag="IT892_002704"
     CDS             23253..24560
                     /locus_tag="IT892_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416271.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HAP3135907.1"
                     /translation="MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAID
                     TRPSAFYNGWPQTLNGPSGHEPAALNLSASWLDKMSTEQLNAWIKQHNLKTDAPVALY
                     GNDKDVDAVKTRLQKAGLTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEV
                     TAKPAGDWKVIEAAWGAPKLYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKH
                     GIRHDTTVILYGRDVYAAARVAQIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKV
                     KAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVSIRSWPEFIGTTSGYSYIKPKGE
                     IAGARWGHAGSDSTHMEDFHNPDGTMRSADDITAMWKAWNIKPEQQVSFYCGTGWRAS
                     ETFMYARAMGWKNVSVYDGGWYEWSSDPKNPVATGERGPDSSK"
     gene            complement(24569..25189)
                     /locus_tag="IT892_002705"
     CDS             complement(24569..25189)
                     /locus_tag="IT892_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416272.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAP3135908.1"
                     /translation="MLDRHLHPRIKPLLHQCVRVLDKPGITPDGLTLVGFAIGVLALP
                     FLALGWYLAALVVILLNRLLDGLDGALARRRELTDAGGFLDISLDFLFYALVPFGFIL
                     AAPEQNALAGGWLLFAFIGTGSSFLAFAALAAKHQIDNPGYAHKSFYYLGGLTEGTET
                     ILLFVLGCLFPAWFAWFAWIFGALCWMTTFTRVWSGYLTLKSLQRQ"
     gene            25276..25683
                     /gene="nudG"
                     /locus_tag="IT892_002706"
     CDS             25276..25683
                     /gene="nudG"
                     /locus_tag="IT892_002706"
                     /EC_number="3.6.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP pyrophosphohydrolase"
                     /protein_id="HAP3135909.1"
                     /translation="MKMIEVVAAIIERDGKILLAQRPAQSDQAGLWEFAGGKVEPDES
                     QRQALVRELREELGIEATVGEYVASHQREVSGRIIHLHAWHVPDFHGTLQAHEHQALV
                     WCSPEEALQYPLAPADIPLLEAFMALRAARPED"
     gene            complement(25649..25921)
                     /locus_tag="IT892_002707"
     CDS             complement(25649..25921)
                     /locus_tag="IT892_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnjH family protein"
                     /protein_id="HAP3135910.1"
                     /translation="MSRALFAVVLAFPLIALANPHYRPDVEVNVPPEVFSSGGQSAQP
                     CTQCCVYQDQNYSEGAVIKAEGILLQCQRDDKTLSTNPLVWRRVKP"
     gene            26157..27500
                     /gene="gdhA"
                     /locus_tag="IT892_002708"
     CDS             26157..27500
                     /gene="gdhA"
                     /locus_tag="IT892_002708"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013366584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAP3135911.1"
                     /translation="MDQTYSLESFLNHVQKRDPNQTEFAQAVREVMTTLWPFLEQNPK
                     YRQMSLLERLVEPERVIQFRVVWVDDRNQIQVNRAWRVQFSSAIGPYKGGMRFHPSVN
                     LSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGA
                     DTDVPAGDIGVGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYF
                     TEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTK
                     EKLARLIEIKASRDGRVADYAKEFGLVYLEGQQPWSLPVDIALPCATQNELDVDAAHQ
                     LIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLG
                     WKAEKVDARLHHIMLDIHHACVEHGGEGEQTNYVQGANIAGFVKVADAMLAQGVI"
     gene            complement(27617..>28040)
                     /locus_tag="IT892_002709"
     CDS             complement(27617..>28040)
                     /locus_tag="IT892_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416276.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HAP3135912.1"
                     /translation="QVIALLNKFAVFPSDYISDCANHSSGKSSAKLIWAAELSWMISI
                     SSTAFQNGTIEEELAWHYIMLASRKVHELFESEEDYQKNSQMGFLYWHICCYRRKLTD
                     AELEACYRYDKQFWEHYSKKCRWPIRNVPWGASSVKYS"
BASE COUNT         6851 a         7421 c         6952 g         6816 t
ORIGIN      
        1 ctacaaaact gtgcaaattc aatatattgc aggaaacacg taggcctgat aagcgaagcg
       61 catcaggcag ttttgcgttt gtcagcagtc tcaagcggcg cagttacgcc gcctttgtag
      121 gaattaatcg ccggatgcaa ggttcacgcc gcatctggca aacatcctca cttacacatc
      181 ccgataactc cccaaccgat aaccacgctg agcgatagca cctttcaacg acgctgatgt
      241 caacacatcc agctccgtta agcgtgggaa acagtaagca ctctgacgga tagtattatc
      301 gataaacgcc ggatgacaca tcacctccag cgaacgatca ccccgatggc ctgcgtcatc
      361 cagcacttgc aggaacagcg actcactgat ctcttcaccg tagaatgcac tgctgaatcc
      421 ctgggtagtg cgcaggttga ccggcaaatc aaacgccatc tgacgatccg cccgcaacgc
      481 aatgccctgc tctgccgcaa acctggcaac aatcgggaaa atctgcggga acatatgcac
      541 atgatgatgg ctatcaagat gcgtaggttt gcgtccaaat agctcaatga aacgcaaata
      601 ctgactgaca agctcctgag taatttcttc cagcggtaaa gcatcttctt ctgccaactg
      661 ccagatccat tttcccagca caccatcgcg ggttaacccc ggcatagctg tcagtggctt
      721 acccatagta aggacaaagt gcatccctat ggccagactc ggttcatcac gactcaactg
      781 caccgcatgg tcaatagcct gcccattcac cagcgccgtc gtcgacgtga caatcccatt
      841 gcgacaggcc tcgataatgc cgtagttctg acctttgctt aagccaaaat catcggcatt
      901 aacaatcagt aagcgttcca taatcagcct cggttaatgt gcttttttaa gctctgcgat
      961 gcagtcggca aagtttggca gccatttctc gtgcgccaga atcatctcgc gtgccagcag
     1021 ctcagcatcg cgatcggaat gcaccaacgg actaaggttt agcgccagta acacatcgtt
     1081 aaattctccg ctaagtgcgg cgttactggc agcaatctcg aagcctttaa tggtgtgaat
     1141 cagccccatt actttatcat cgaaatgcgt aatgcgcgga tgtggcgtcg cgccatcgcg
     1201 ccccagctta caggtcattt ctactgccca gtctgccgga atattatcaa tctgcccatg
     1261 atgcgggata ttaacgtaat gttctgcttg cttgtcgttg tagatagcgt tgatcacttc
     1321 gcatgctgca tcagagtaat aagccccacc gcgctgttcc agttctttcg gcttaacttt
     1381 cagctcagga tttttataca gctcaaaaag ttgtttctcg actttctgta ctacctgcgc
     1441 tcgtgcgccg cctttgtagt attcgcccat ttcaatagcc agcatctctt tctgcttgaa
     1501 gtaatacagc agataagaac atggcagcag attcaacgaa cgaattaagc cctcactaaa
     1561 tggcagatcg aaaatatttt ttacagagga cgcttttaac tgccctgacg ccacaccatc
     1621 aagcaattcg gcaaagcgcg acttgccatt taccagcaca tccttaatga acaccatatg
     1681 gttgaggccg aacaaatcga tagataaatc atcgctgtct ttcagcatca gaacatcgcg
     1741 aataaacatc ttcatgccga tcggaatatt acacacgccg ataaagcgtt taaatccggt
     1801 atgacgataa acggcttcag tgaccattcc cgccgggtta gtgaagttaa tcacccatgc
     1861 attcggacaa agttcttcga catcttttac gatgtcaaaa atcaccggaa tggtacgcag
     1921 acctttaaac aaaccgcccg cgccgttggt ttcctgacca agataaccat gacttaatgg
     1981 aatacgttca tccagttcac gcgccggtaa ttggccaacg cgcagttggg tagtaacgaa
     2041 atcagcatct ttcaatgctt cgcggcgatc cagcgtttta taaagcttca tcgggacgcc
     2101 agcgttatca atcatccgtt ggcagagatc gaaaataata tccagtttcg gtttaccacc
     2161 ttcgacatcc accagccata attcgctgac cggcaattcg tgataacgct taataaatcc
     2221 ttccagtaac tccggggtat agctgctccc gccaccaata gtgacgactt ttaatttctg
     2281 gctcataatt tctcccttca gtacagaata ctgatatctg gcatatctgc ccccccggac
     2341 ataaataatc cagcaacagg acagatatgt gaattgtcag gtataacgac ttactgatta
     2401 aattcagtca atttcttacg atagctctta ggcgtaaagg acgttaattt cttaaacgtt
     2461 ttaataaaca aactcgggct actataaccg gcctcaaacg caatatccgt cactgaatag
     2521 ttggtcattt ccagttgttt tttggcaaaa ttaatacgga tttcattaat aatctgcatt
     2581 ggcgttttgc cataatatcg ttgagtcgct cgcgtcaaat attcctgtga tttggctgac
     2641 aacgccacca tattctccag cgccgattca ctaaactgct ctttatcatg catcttttct
     2701 accgtacttt tcagccactg cggtacatca tcaatcacct gttcttcgcg gtaatgacgt
     2761 aaacggttaa tgacataaaa agtaaccatc tcaacaaact cttccagccc tgtttcgcgg
     2821 aaattcaatg aagaaatcac tgtttccaca taggtgagaa aagcgttatt ggtccggtat
     2881 acctgcgaag cgacaaagca ataaggcaac aatggcaggt aatgctgctc aaaaaagcgt
     2941 ttactgatcc caacgttcaa tatgcgcgtg gcaccaaact cataaaaact ttgatggtgc
     3001 gaacctaacg gaataaaaac aaaatcgccc cgttccagta acacgcgctt accgttaatc
     3061 tcctggaaat aacgcccggt taataccaga gtaaattcat aatagtcgtg ctgatgcagt
     3121 ccgctgatac tctcagtttt gttatagata aacacatgga agtttttgcc attaaacaac
     3181 tgctgttctc gggcagtggc aatttccggc gcgttaatca ctggctgcat catcgactcc
     3241 ttatgccttc agtttttcat gaagctcaat taattcagta atcagttcac gcgcaagcat
     3301 ggacgtcatt aaatgatcct gagcgtggac cagcaccaga ctcactttca tcttaccttc
     3361 gcccgcatcg ccttcaatca gtttcgtctg taccagatgc gcttcattca atgccatccg
     3421 tgactgatcc atcatggctt ttgctgcggc aaaatcgccc tgcttcgcct gtttcagtgc
     3481 cgcatacgcc aggctgcgcg cttgtccgga gttgatgatc agccccatca ccacttcttc
     3541 cagctcttca gcttccgttt gcgtatcggg attgttatcg agatccatca tacatcgttc
     3601 ctctcttttc ttaccggcac gattacccgt accggcatcg attaaaattt cagggcgtta
     3661 gcgatatctt cttcgctctc ttctttatca atcgcatttt gtgctttgtt agccaccaca
     3721 acaaagggca gataaattaa cgttgcgatg ccaaggttga agagtgcgac cagcaatgcg
     3781 gcgacgctac cgttggtgtt aaagaaggct cccagaccgg ttggcatggt ccacggtgca
     3841 atattggtca ccggaggaat aatgcccatg tagtacgctg cgagggtgat tgccgccaga
     3901 atcggttgta ccagtacaaa cgggataaac atcaccgggt tcatgataat tggcagacca
     3961 aacagaatcg gttcgttaat ctggaagatg ccggacggca gcgccagttt tgccacctga
     4021 cgataatcag cacggcgaga ggcgataaag atagccagga tcaggcctaa agtcgcacca
     4081 ctgcccccaa ggaaaataaa ggagtccagc atcggcttgg cccagatatg gaaggtctta
     4141 ccggctgcca gcgccgcttc gacggaacca tattgctgat aggtcgcgat attttccagt
     4201 gcccacggcg tcataatgcc gttgtccagt gcggtcagcg ccagcgcgcc atgaataccg
     4261 aagaaccaga gcagtggaac aaagatcaca taggcccagc ccaccacgct acccaacgat
     4321 gccagtgggg ttgagatggt atccataatg atctgatgga agttggtgcc ccaggtattc
     4381 aacgcccagg caataatccc catcacggaa agaataataa agccgggaat taatgccgag
     4441 aaggaacgcg atactgaagc aggtacgctg tcgggcagtt taatgaccca attgcggcgg
     4501 acaataaagg taaacatttc tgccaccacc aggccaataa taatcccgga gatgatattc
     4561 gccccaccta accagtttgc accaaccgca taggcctcac cgacactata tggggtgacg
     4621 gtcataaatg ctgcaacgga taacaaccca gccgccagcg catcgacttt acgctcttct
     4681 gccagcgcca tgccaataaa gaacggtgcc attaaagaca ttattcctaa tgttccgtta
     4741 tatacgttgc cgccaatacc tttcagacca ttaagtgttt caatggttga ggcgtcgagg
     4801 cgaataccta aggaataaaa aaacgacccc tccccaaagc ttagaaaaac gttgttaatt
     4861 aatacaaaca tggcccccgc aagggttaac ggcattaagc gaataaagcc atttttgatt
     4921 gcattaacgt gtggctgctt tcctatttta actgcaaaag ggaggagtac cttttcaagc
     4981 gatgcaataa cattactcat agaaaaatac ccttaaaaac cgcaatttaa atattgcggt
     5041 attgatttat gaaataactc tttgacggga aaatttaaaa taaattaatt tgctgcggct
     5101 tttttaatcg ctgcaaccgc agccttaagc acgcctaaac catcgacttt gccataaagc
     5161 agcgagtcaa ttacttcaac cggtttgttg ggtaacaaac gctggatttc gggcaacata
     5221 taagcaatct gcggccctaa taacacgaca tcggcattct gacctttttc accagccagt
     5281 gtttccggaa atgcttcaat aatgaccgga acttcatatt tttctgcctg tgcgcgcatt
     5341 tttgatacca gtaaagaggt agacatgccc gcagaacaaa acagataaat gtgtttcttt
     5401 tccataaaac tgccctcatc gacgattatc tgtcagccag acactccgca agccttaacc
     5461 tgcttccatg ctctgggtaa cttgcgaaac caacatgact ttttttgtgg ctgaaaggag
     5521 tatacggtat agacctgagc aatagtattt ctttgacctt ataaattgtt tctccttgac
     5581 ctgtggttat gaccctcttc acatttcggg caaataattc gcgaagataa ttaagaactc
     5641 aggccaaaaa aaaccggcgc aatggccggt ttccgttgtt actcaagctt tcagacgaat
     5701 tgattacttc gcagcctgtg gatcagtgtc gtattcagca caggtctgat aaccggagtt
     5761 gatgacatgt ccggtatcat ctaacgcgac aaagtaggtt tctgctttac catcacgttg
     5821 acccaggatg taggtctggc aagtaccgcg agcatggatc atgctcactt cagacgaagg
     5881 tttacccgca atttgtgcaa cctgcgcccg gctcatgcct tttttgacgt ctttcaccac
     5941 aggctgtaca aactggtctt tggtacgatc ataagccgta caacccgcca gcatggttaa
     6001 taccgccgct gcactcagaa ttcctgccat attcttgttc atattccgtc ctcttgttta
     6061 tcagcgtgtt agataagcct ggaatacatt gggcgctttt tcaagcccgt gaacgaaacg
     6121 gctccgcttt cagaggattc ctgtatgacg ttttaaccac cattcagccc gctgtcgctt
     6181 gtcgtttcag tagcaacggg ttagctttaa ggaagttttg tcttttctgt ctggaggggt
     6241 tcaatgacat tgcaacaaca aataataaag gcgctgggcg caaaaccgca gattaatgct
     6301 gaagaggaaa ttcgtcgtag tgtcgatttt ctgaaaagct acctgcaaac ttatccgttc
     6361 attaaatcac tggtgctcgg gatcagcggc ggtcaggact ccacgcttgc cggaaagctg
     6421 tgccagatgg cgattaatga gctgcgcctg gaaaccggca acgaatcact gcaatttatt
     6481 gccgtacgcc tgccctatgg tgttcaggcc gacgaacaag attgccagga tgccattgcc
     6541 tttattcaac cggatcgcgt attaaccgtt aatatcaagg gcgcggtatt ggccagcgaa
     6601 caggcattgc gggaagcagg cattgaactg agcgattttg tccgtggcaa tgaaaaagcg
     6661 cgtgagcgga tgaaagcaca atatagcatt gcgggtatga ccagcggtgt cgtggtgggc
     6721 accgatcatg cagcagaagc cattaccgga ttcttcacta aatatggtga cggcggtacg
     6781 gacattaatc cgctgtatcg tctcaacaaa cgtcagggta aacagttact ggcggcatta
     6841 gcttgcccgg aacaccttta taagaaagcg ccaacggccg atctggaaga tgatcgccct
     6901 tctctgccag atgaagtggc actcggcgtg acctatgaca atatcgacga ctatctggaa
     6961 gggaaaaacg tacctcaaca ggtcgccaga acaatagaga actggtatct gaaaaccgaa
     7021 cataaacgcc gtccgccaat taccgttttc gatgatttct ggaaaaagta ataatttgca
     7081 catattggat tgtgcgaaaa agagtaattt gttcacgccg gatgcggcgt gaacgcctta
     7141 ttcgacctat aaaactatgc aaattcaata cattgcagga gtcgaatagg cctgacaggc
     7201 gtagcacgtc agacggtgta acctttgtca tcgacccgcc tcttttttaa tcgcttcccg
     7261 cctgttacac tggatagata accagcattc ggagtcaaca gtggtacggc gtttaacttc
     7321 tccgcggctc gaatttgaag ctgcggcaat ttatgaatat cccgaacatt tacgttcatt
     7381 ccttaatgac ttacccaccc gaccaggggt gtatctgttt catggtgaaa gtgacaccat
     7441 gccgctctat atcggcaaaa gcgttaacat ccgcagccgc gtcctttctc atttacgtac
     7501 cccggatgaa gccgccatgc tacggcaatc ccgacggatc agctggatat gtaccgccgg
     7561 tgaaatcggc gctctgctcc ttgaagcgcg attaatcaaa gaacaacagc cgctgtttaa
     7621 taaacggttg cgccgcaatc gccagctctg tgccctgcaa ttaaatgaaa agcgcgtcga
     7681 tgtggtgtat gccaaagagg tggatttttc acgagccccc aacctgtttg gcctgtttgc
     7741 caataggcgc gcagctttgc aagcattgca gaccatcgct gatgaacaaa aactttgtta
     7801 tggcctgctg ggactggaac cgttaagtcg cggtcgtgca tgttttcgtt cagcgctaaa
     7861 acgttgcgcc ggagcatgct gcggtaaaga gagccatgag gaacatgcgc tacgcttgcg
     7921 ccagtctctg gagcgtttgc gggtggtgtg ttggccttgg caaggggcgg tggcgctgaa
     7981 agaacagcac ccggaaatga ctcaatatca tattattcaa aactggctgt ggctgggggc
     8041 ggttaattcg ctggaagaag cgacaacgtt aattcggaca cccgccgggt ttgatcacga
     8101 cggttataaa attctttgta agccgctgct ttccggtaac tatgaaatta ctgaacttga
     8161 tccggcgaat gaccagcgag ccagttgatt tcactgaaca acagtttacc ttgcggttgt
     8221 aaaagccgca gggtgtgcct gccatcgaac cagcacgcgc cctggtcggt agtgagcaat
     8281 ttatcgccca gttgccacgc cccgttaatc acaaacacca ccccgccgcg tgagccaaag
     8341 gtagtaaacg tacgttcggc aattctgact ttcgccttac agacatccag gcgtgtcatg
     8401 atgttgaaat ccatcgacat ctgccctgcc gtcagtttcg cttttaccac ctggtccgct
     8461 gcaaaggcaa aaggctggaa cggttttaag gtatggttaa agcggtctgc gctttcaagg
     8521 agcatctcgc cgccttccag caacgtcact atcctttcca tgccgggaaa caaagaaaac
     8581 tccccattcg ccgcgatgga tgcaatgctg gcacgccagt aaaaatcacg ttttgccggt
     8641 gggaacgtgc aaatttcgcg cgtttcaccg gcagcatttc gccacagatt caccgacatt
     8701 ttacgcatat caaagtattc catactcgct cccggcccgt tcttttcatt gttatcgttc
     8761 aggtaaccgt ggatggttat cggcaactcg ggtgatttac gttagtggtg atcaggcttt
     8821 ttttacaact gtttgagaag agaaaagaaa accgccgatc ctgtccaccg cattactgca
     8881 aggtagtgga caagaccggc ggtcttaagt tttttggctg aaagattatt cagcagttgc
     8941 aggcatttta ccttttgccg ctggacgttc tgtcagacgc ttctcaaaat tagcattaaa
     9001 ttgctttttc tgttccggcg tcaggatgtt gtaaattttg ttctgggttt ccatgtgcgc
     9061 cagcatgtta gctttgcgct gttcttccat ttttgcgatc tgcgcttcag cttttacttt
     9121 atcgaaggta tcgctggcaa tgatgtcatg cattgcgcgg cgttcttcca gcggcggacg
     9181 tttcatctgg tcacgctggc ctttcatgat ttcgcggatc tgctgtttct gcgcgtcggt
     9241 caggttcagg tctttgaaca tcatgtcctg atgcggaccg aacttgcctt tgtggtgcat
     9301 catcggcttc gcgtcagccg gtgctgcggt agtggtgtct gcggcatggg ccaggttagc
     9361 cgcgccaaga gccagggtag aggcaacaaa cagtgcagtt aatttacgca tattctatat
     9421 ccttcctttc agttatttat tacggctttc ttaagtagcg tgccgtgttg acgagattaa
     9481 ctttactgac tttagcgtca attaatcaga gcaacggtaa aacaatgaaa gtgtaaaaaa
     9541 cacttttgcg ccaattatgg agaaaaaaag aaaatttgat ggagagtgat gagagaatat
     9601 tacaacacga tgattttgca gagattatga agaactatac cggatgactg gtgataaata
     9661 aagcaaataa ccaggattaa tctgtattaa tttataagaa agcaacttaa tacccgcaga
     9721 atgatttctg cgggtaagta ttagcttatt ttttcgagca ttaatcccgc gcgtaatccc
     9781 aacgctacca acggattagg gaataacaca tactctacat catgggttac ggtaaaacgt
     9841 tcctctccgt cctgcgccag caatgttcct ttctcaaacg gcataaaatt cagcgtgtca
     9901 cttgccatat gcatttcgaa ggacggcgag tggcgagtaa tttgcgaaac cacccgataa
     9961 cggagcggcg gtgttctcac gataccgaca ctctcaccag atagcagcgc agcaattgcg
    10021 ctggcagtta ctgcaaactg gcgaagatcg ttttgcccaa agggcaacgc tttgccaagt
    10081 tccagcgtac aggccagcgc gccaaaatgt ctggcgctga aatgggtaaa cgtaccacca
    10141 ggttcctgat ggaacaccag cgcctccagc cccgccgcac ccagccacgt cagaaatttc
    10201 tcgtcccagg gaatgtcgcg ttgcggtaat acaccgaact gcggatgcaa ggagccacga
    10261 attgcggtat gtagatcaag gtgccagcgc acagattctt tgccctggtc ataaaaatct
    10321 tccaggcact gttccagttc gcgcgcccga caggtttctc cgctttcagc aaatagctgc
    10381 caacgaccgc caaacattcg attcatatcg ctatggcaat aacgtttccc ttgcttcagc
    10441 gcaggaggat tcccgaggat caccagcaac cgccaacgta acgggatctc gccgtgagat
    10501 atcgcgccaa gcaacgcgtc cagcatctcc acaggtgccg tctcattacc gtgtattccc
    10561 gctgaaatca ccagtgcgcc ttgcggtggc gttaatggcg tcagttccag cacaccatcg
    10621 cccagccagc gccagcgaac gccgttgatt tctcgctcgg tgataaccgg ttttttaccc
    10681 gttaaggtca gagcaagaaa attatccatt gccccctccc tcgcgctgga acggataaac
    10741 cgaaccgaga ttcagtaatt ggctcaatac atccagtgct tcccgccctt cgcgcagcaa
    10801 ttgcgggtcg gccagatcgg cagcagtaag gcgatcgcgg tagtaacgat ccacccagtc
    10861 attgagcgca ttaaacagcg tatcgttcat catcaccgcc ggattcaccg cccggcgttc
    10921 ttcttctgtc aataccaccc gcaaccgcag gcacgccggg ccgccgccat tcgccatgct
    10981 ttcacgtaaa tcaaagactt ttagttcgct aatcgggttg tcagcggcaa ggagttcatt
    11041 gagataaccc catactccgg cgtgttcccg acactcctga ggcagcacca acatcatgga
    11101 accatcatcg cggctcagca gttggctgtt aaacagatag gtagacaccg tatcagacac
    11161 ggaaacctga gttgccggaa cttctatcgc cataaaacca ttgacccgcg cacgcaggtt
    11221 tgccagtaac tgtgactggc gagcgaacgc ctgttggtgg caaaacagca cctggcggtt
    11281 actcacggca atcacgtcat tatgaaaaac gccctggtcg ataacgtccg ggttttgctg
    11341 ggcgaaaatc acctgttggg gattcacctg attcagcctt gccaccgcct cgctggcttc
    11401 gcgagtctgt cgcgccggat aacgggaagg ccgggtatca ttgccttctt ctcgcccgta
    11461 gacaaaaagt tgcatacccg gttcaccgta atgaccgccg agacgattgt ggtttgccgc
    11521 cccctcatca ccgagcaacg ctacctgtgg caacgccgaa tggacgctaa atttctcttc
    11581 gtcgttaaaa atcgctttta acagcgattc agtgacgggc gcttccagcg aacggtgaaa
    11641 tttattgttc aggttggcaa cggtgagatg cactttgcca tccagcgtat cggcagatgg
    11701 cgcgatcgtt gccgcattgg ctacccacat tggcgaagcg gaactgacgc tggaaagcca
    11761 gtgcggtgcc tggcgtgcaa ctttttccag tacctgctca tcgctaccac tgaatcccaa
    11821 ctgacgcagc accggaataa acggacgctc gtgcggcggg atcacggcct gggggaatcc
    11881 cgcatcggca agggctttca ttttcagtaa gccctgcttc gccgccagtc gcgggttaga
    11941 cacctgaaaa cggtgacggg tagaggcttc attaccaaac gacaggcccg cgtaatgatg
    12001 cgtcagccct accagcccgt cgaaattgac ttcccaggcg ttcatcgcac cacctcatcg
    12061 gaaaaatcca gcccggggtt aagcgtggcg ggcaatgtta acgagtccga ctccaggctc
    12121 gccatcggcc atgcgcagta atctgcggca taccaggcgc tggggcgatg gttaccggaa
    12181 gcaccaatgc cgccgaatgg cgcggtactg gcagcaccgg taagcggttt gttccagtta
    12241 acaatccccg cccgcgcctc cagcaacagt tgatcgaact tttcccgctc gggggaaacc
    12301 agaccgcaag agagtccgaa gcgagtgtta ttcgccattc gaatcgcttc atcgaaagta
    12361 tcataacgcc agacgcgcaa taacggtccg aacacctctt catctggtac gccagcaacg
    12421 cctgtcattt caatgatccc cggcgtcagc aacgatgtcc ctgcttgtaa taagcgcggc
    12481 gcaagcaggg gtcgtccgcc catcgcttcc agttgctgcc atgcagtaac cacctgctgt
    12541 gcggcctgtt cagaaatcag cccgccaata aacggctgcg gttcgtcatc ccagttgccc
    12601 ggcgttaatc gctggctgac ggcaaccaga cgagcaagaa acgcatcgcc ctgcgccccg
    12661 cttttcagca ataaacggcg ggcgcaggtg cagcgttgac cggctgtgac aaacgccgac
    12721 tgaatggtca gatggacagc cgcgtcgata tccgccacct catcgataat tagcggatta
    12781 ttaccgccca tctcaagggc gagaattttc tccggctgac cggagagctg gcgatgcaac
    12841 tggtagcctg tattggcgct accggtaaac agcaaaccgt cgagatcctc cagcgcactc
    12901 agcgcctgac ccgtttcacg cccgccctgc accaggttca gcacgcctgg cggcaagcca
    12961 gcctgctgcc ataaacgcat taccgcttcg ccactccacg gtgtcagttc gctgggttta
    13021 aagataatgg tgttacctgc cagcaatgcc ggaacgatat gtccgttcgg caaatgacca
    13081 gggaaattat acggcccaaa caccgccagc acgccgtgcg ggcgatgtcg caggctcgcc
    13141 gcgccgtccg gcatttcact acgctgctcg ccggtacgaa cgtgatacgc cttaattgat
    13201 atcgcgattt tattgatcat cgccgtcact tcggttgccg cttcccagcg cggcttaccc
    13261 gtttctctgg caataatcgc ggttaattcg gctttattgc tttccagcag tgcggcaaag
    13321 cgttcgacaa cggcatgacg ttcagcaaat gaaagccgcg cccagcgcgg aaacgccgca
    13381 cgggctgccc gacaagcctg ctcgacctga gcggcatcgg catcattgcc ttgccataac
    13441 acctcgcccg ataccggatt acgcttcaca cgcgatgcgc cctggcccgt tatccagtca
    13501 ccgttaatcc ataaagtcat gctgttttct cctctgcgca caggcgcacc agacgaacgc
    13561 gatccccggc gtggcatttg agggcatcca gttgtgcggc ggttaaaatc aaacgctcgg
    13621 ttgccggatc ggtacgcacc agcaccacgc ggaaatggtg ataattttca ttggcgacca
    13681 ggcaggctgg gaaatcgccc tgcgcaggct gcccttctgc cacttccacc agccgacttt
    13741 tacggatggc gcgcacgcgg tcgatgtcac actcaagcgt cggcccaccg tcaaagatgt
    13801 cgatatagtt acggtagcga aaaccttctt tctccagcac cgcgcgggca ggcgcggttt
    13861 gcggatgtac ctgaccgatg acgtcctggg cttcctggga taaaaagtgg gtatagatcg
    13921 gatgtttcgg catcagttct gcaataaatg ccttttgccc ggtgccgcag agaaaatcgg
    13981 cgcggctaaa atccatcgaa aagaagcgtt taccgaggct ttgccagaac ggtgaatagc
    14041 cgtgttcgtc aatcaccccg cgcatttcag caaccacttt gtcattaaac ttgtcgcgaa
    14101 aagccgccat aaacataaag cgcgatttcg acagcaaata gccgttgccc tctttgcgcc
    14161 agtccgggtc gagaaacagc gtgcacagct cgctgctgcc ggtgtgatcg ttactgagaa
    14221 acagcgtcgg caatgcgtta tagacattca gctcttttga ggcgtgaacc aacgtgccga
    14281 cgcgatagtt gtaccaggga tcgttcagcc caaccgccac ctcaatggca caaatccccg
    14341 ccacggtgcc tgtctcgcta tcttccagca cgaacacata gccctgctca cttttgggca
    14401 gttcgccttg ccaggttttg attgcccttt cgatacgcgc cgaaagcgtg gcttcattgg
    14461 cgggaagcga cgtcaggccg ccgcccgttt tgctggcaag ctgcatcagc gccgagacat
    14521 ctgatcgctc aacgggacgg atgaccatca tgatgaacct cggctaacaa agtgttcgca
    14581 agcagctgca aagcgatcca gtccggtcgt cacctcttct tcgctgacat tgagcgcagg
    14641 cgcaaaacgc accacgttgc cacccgcaat cagtaccatc acgcctgctt tcgccgcttc
    14701 ctgagagatc tgtttcgctt gcccggcgta atcggcattc agtacacagc caatcagcaa
    14761 acctaagccg cgaacttcac tgaacaaacc atagcggtga ttaatagtat taagacgctc
    14821 aacaaaccag tcgtgacgct gtttaacgcc attaagcatc tctggtgtgt tgatgagctc
    14881 cagcactttg cctgccaccg ccgaggccag cggattaccg ccataggtgg tgccatgagt
    14941 gccaacggtc atcacgcggg cgcactcttc ggttgccaac aacgcaccga ccgggaaacc
    15001 gccgcccagc gctttggcgg tagttaacag atcaggcgtc acgccgtagt gcatataggc
    15061 atacagttcc ccggtgcgcc cgacgccggt ttgtacttca tcaaaaatca acagcgcatt
    15121 gtggcggtta cacaattcac gcagaccttg taaaaacgcg ttgctggctg gcaccacacc
    15181 gccttccccc tggatgggtt cgacaatcac cgcacaggta gagtcgtcaa tcagcgcgct
    15241 ggcagagtta atatcgttat atgcagcatg acgaatatcc gccggcagtg gcgcaaaatc
    15301 ctgtgaatag gctggctgcc cacccgcact gacagtaaac agcgtgcgac catgaaacgc
    15361 atttttgaac gccacgatgc cgctcttatg gctgccgtag cggtcgtgag cgaatttacg
    15421 cgccagtttt agcgccgctt cgttggcttc cgcaccggag ttacaaaaga agacgcgatc
    15481 ggcaaacgtg gcgtcgatca attttttcgc cagtcgcagt accggctcgt tggtgtaacc
    15541 gttgccggta tgccagaact tactcgcctg ttcgttcagc gcttcacgca gttccggatg
    15601 cgcatggccc agcgcgttca ccgcaatgcc acccgcgaag tcgatatact ctttcccctg
    15661 ctgatcccac aagcgcgaac cttcgccacg taccggtata aagggtgccg gagcgtaaac
    15721 aggtatcatc cattcatcaa agttttcacg cgtaattggc tgagacatag cgacctctac
    15781 agtaaataat tcgttattta tatgttaata ataagtaatg tttgcgctgt aaatgtagat
    15841 tgcagggttc gtgccagcca gtgataaaag tgcataaacg gcggaggcta actggaaatc
    15901 aaggagttat aaccaaacca tatgcattta aagtgcatat aaagtgaata cgtttgcgat
    15961 gtgggtgaat aaaaagaata aaaaacgcaa tgttatgcag aagtaaaata taattctgga
    16021 attgtgatca ttgacgaaat ttactggaaa ttactgcgcc attctgacgc agcgcgcacc
    16081 aaaagcgggc attttttgcg ccatcgttga catcattaac aaccatcgat caaatcactt
    16141 aacaacaggc ggtaagcaac gcgaaattct gctaccatcc acgcactctt tatctgaata
    16201 aatggcagcg actatgaaat ttgtctcttt taatatcaac ggcctgcgcg ccagacctca
    16261 ccagcttgaa gccatcgtcg aaaagcacca accggatgtg attggcctgc aggagacaaa
    16321 agttcatgac gatatgtttc cgctcgaaga ggtggcgaag ctcggctaca acgtgtttta
    16381 tcacgggcag aaaggccatt atggcgtggc gctgctgacc aaagagacgc cgattgccgt
    16441 gcgtcgcggc tttcccggtg acgacgaaga ggcgcagcgg cggattatta tggcggaaat
    16501 cccctcactg ctgggtaatg tcaccgtgat caacggttac ttcccgcagg gtgaaagccg
    16561 cgaccatccg ataaaattcc cggcaaaagc gcagttttat cagaatctgc aaaactacct
    16621 ggaaaccgaa ctcaaacgtg ataatccggt actgattatg ggcgatatga atatcagccc
    16681 tacagatctg gatatcggca ttggcgaaga aaaccgtaag cgctggctgc gtaccggtaa
    16741 atgctctttc ctgccggaag agcgcgaatg gatggacagg ctgatgagct gggggttggt
    16801 cgataccttc cgccatgcga atccgcaaac agcagatcgt ttctcatggt ttgattaccg
    16861 ctcaaaaggt tttgacgata accgtggtct gcgcatcgac ctgctgctcg ccagccaacc
    16921 gctggcagaa tgttgcgtag aaaccggcat cgactatgaa atccgcagca tggaaaaacc
    16981 gtccgatcac gcccccgtct gggcgacctt ccgccgctaa tttagcagct ctcctggctc
    17041 aaactgggtc aggagaatta accttgagaa aaatcaacaa actgtcagta atgatttgtt
    17101 gcctgccgtc ctttgttata ccgtctctgc gtttttagtt gtctgaccac ttctctatta
    17161 tcaagtttga tataggaaac tccacgatga acgctgagcg taaatttctt tttgcctgtc
    17221 ttatttttgc gctggtcatt tacgctatcc acgctttcgg tttattcgat ctgctcaccg
    17281 atttacccca cttacagaca ctcatccgcc agagcggatt tttcggctat agcctctata
    17341 ttctgttatt catcattgcc accctcttgc tgttaccagg aagcatactg gtgatcgcgg
    17401 gaggaatagt ttttggcccg ctcttaggga cactactctc attaattgcc gccacgctgg
    17461 cctcctcgtg ctcattcctg ctggcgcgct ggctgggacg tgatttactg ctgaaatacg
    17521 ttggccatag caataccttc caggccattg aaaaaggcat tgcgcgtaac ggtattgatt
    17581 ttcttattct gacccgctta atcccgttgt ttccttacaa tattcaaaat tacgcttacg
    17641 gattaaccac aatcgccttc tggccttata cccttatttc ggcactcacg accctacccg
    17701 gtattgttat ttataccgtg atggcaagcg atctcgccaa tgaaggcatt acgctgcgct
    17761 ttattttaca actctgtctg gcgggcctgg cgctgtttat tctcgtccag ctcgcaaaac
    17821 tctacgcccg acacaaacat gtggatctgt ctgcttcgcg ccgcagccca cttactcacc
    17881 caaaaaatga aggatagaac gatgttgcaa cattattcag tgtcatggaa aaaaggactg
    17941 gctgcactct gtttactggc tgttgctggg cttagcggct gcgatcaaca agagaatgcg
    18001 gcggcaaaag tggaatacga cggactttcg aacagccaac cgctgcgtgt cgatgccaat
    18061 aaccatacgg taaccatgct ggtgcaaatt aatggtcgtt tcctcaccga cgacactcgt
    18121 cacggtattg tgtttaaaga tggctccaac ggacataaat cgctgtttat gggttatgcg
    18181 accccgaaag cattttatga agccctgaaa gaggcaggtg gtacgccggg cgaaaacatg
    18241 acgatggata ataaagaaac gactcatgtc acaggcagca aactggatat ttcggtcaac
    18301 tggcaagggg cggcaaaagc gtattccttc gatgaagtga ttgttgacag taatggcaag
    18361 aaactggaca tgcgctttgg cggtaattta acggcagcag aagagaagaa aacgggttgc
    18421 ctggtgtgtc tggatagctg cccggtcggc atcgtcagca atgcaacata cacttatggt
    18481 gcggttgaaa aacgtggtga agttaaattc aaaggcaatg cctcagttct cccggcggat
    18541 aacacgctgg caacggttac ctttaaaatc gccgaataaa gccaggataa aggatgatga
    18601 tgatgcaatc gcgaaaaatc tggtactacc gtataaccct catcatcctg ttgttcgcta
    18661 tgctgctggc atgggcgctg cttcccggcg tccatgagtt tatcaatcgc agcgttgcgg
    18721 cgtttgccgc cgtggaccaa cagggtatag aacgctttat tcagtcttac ggcgcactgg
    18781 cggcagttgt ctcgttcttg ttgatgattt tgcaggccat tgctgcaccg ctacctgcgt
    18841 ttttgatcac ctttgccaat gcgtcgctgt ttggcgcgtt ctggggcggc ttgctgtcgt
    18901 ggaccagttc gatggccggc gcggcgctgt gcttttttat cgccagagtg atgggccgcg
    18961 aagtggtgga aaaattaacc ggcaaaaccg tgcttgacag tatggacggc tttttcactc
    19021 gctacggcaa acacaccatt ctggtctgtc ggttattgcc ttttgtccct ttcgatccaa
    19081 tcagctatgc tgccggtttg acttcaatac gttttcgctc gttttttatc gccaccgggc
    19141 ttggtcagtt accggcaact attgtttatt cctgggcggg cagcatgtta acaggcggta
    19201 ctttctggtt tgtcaccgga ctgtttattc tgtttgccct gaccgtggtg atttttatgg
    19261 cgaagaaaat atggcttgaa cgccagaaga ggaatgcctg atgggtttac cgccgcttag
    19321 caaaattcct ttaattttac gtccacaggc gtggctgcat cgtcgccatt acggcgaggt
    19381 gctaagcccc attcgctggt gggggcggat cccgtttatc ttttatctgg tgtcgatgtt
    19441 tgttggctgg ctggagcgca aacgctcacc gctcgatccg gtagtacgat cgcttgtcag
    19501 cgcgcgcatt gcgcaaatgt gcctgtgtga gttttgtgtg gatatcacca gtatgaaagt
    19561 cgccgagcgc accggcagca gcgataaact gctggcagtg gctgactggc ggcaaagccc
    19621 gctctttagc gatgaagaac ggctggcgct ggagtacgcc gaagccgcaa gcgtaacgcc
    19681 gccaacggtc gatgatgccc tgcgtacccg actggctgcg cattttgacg ctcaggcgct
    19741 caccgaactg acggcattga tcggcctgca aaatctgtca gcccgtttta attctgccat
    19801 ggacattccc gctcaggggc tgtgccgtat tcctgaaaaa cgttcttaag gagagatgat
    19861 gcgccattgt gggtggttgc tgggattgtt atcgctgttt tctctggcaa cacatgccag
    19921 tgactggcaa gaaattaaaa atgaggccaa agggcaaacc gtctggttta acgcctgggg
    19981 cggcgatacc gcaattaacc gctatctcga ctgggtgagc ggcgagatga aaacccatta
    20041 cgctataaac ctgaagattg tccgtctggc ggatgccgca gacgcggtga agcgcattca
    20101 gaccgaagcc gcagccggac gtaaaacggg cggctcggtg gatctgctct gggtgaacgg
    20161 cgaaaacttc cgcaccttaa aagaggccaa tttattacaa acgggctggg cggagactct
    20221 gcccaactgg cgctatgtcg acacacagct gccggtgcgg gaagattttt ctgtgccgac
    20281 acaaggtgcg gaatcgccct ggggcggcgc acaactgacg tttatcgccc gccgcgatgt
    20341 tacgccacag ccaccacaaa cgccgcaagc cttactggag tttgctaaag ccaatcccgg
    20401 cacggttacc tatccgcgcc caccggactt taccggcacg gcgtttcttg aacagttgct
    20461 gattatgctg acgcccgatc ccgccgcatt aaaagaagcg ccggacgatg cgactttcgc
    20521 ccgtgtcact gctcccttgt ggcaatatct tgatgtgctg catccgtatt tgtggcgcga
    20581 aggaaaggat ttcccgcctt cacccgcgcg gatggatgct ctgctgaaag ccggcacatt
    20641 gcgcctgtcg ctgaccttta accccgcgca tgcgcagcaa aaaatcgcca gcggcgattt
    20701 gcctgcaagc agttacagtt ttggctttcg cgaggggatg attggcaacg tgcatttcgt
    20761 caccattcct gccaacgcga atgccagtgc tgcggcgaag gtagttgcca atttcctgct
    20821 ctcacccgat gcgcaactgc gtaaagcaga tcccgctgtc tggggcgatc cttctgttct
    20881 cgatccgcaa aaactgcctg acgggcagcg cgaatcattg caatcaagaa tgccgcagga
    20941 tctgccgccg gtactggctg aaccgcacgc aggttgggta aatgcgctgg aacaagaatg
    21001 gctacaccgt tacggtacgc attaatcttt ttgctgtggg cgatggtggc ggtgatttat
    21061 gcaccgctga tcccggcagc tctcacgctg atatcgcctg ctttgtcgtt gacacactgg
    21121 caggcgttat ttgccgatcc acagttaccg caggcattac tggcaacgct ggtgtcgaca
    21181 accatcgcgg cggtcggggc attgttgatt gccctgctgg tgattgtggc gctgtggcct
    21241 gggccgaaat ggcagcgtat gtgcgcccgt ctgccgtggc tgctcgccat tccccatgtg
    21301 gcttttgcca ccagcgccct tctgctcttt gctgacggag ggctgcttta tgactatttc
    21361 ccgtatttca ctccgccaat ggaccgattt ggcatcggtc tgggcctcac ccttgcagtg
    21421 aaagaaagcg catttctgct gtggatctta gcagcagtat tgagcgaaaa atggctgttg
    21481 cagcaggtca ttgtgctgga ttcgctgggc tacagccgct ggcaatgcct gaactggctg
    21541 ctgttgccct ccgtcgcgcc tgcgctggca atggcgatgc tggcgattgt tgcctggtcg
    21601 ctgtcggtcg tggatgtggc aattattctc gggccaggta atcccccgac gctggcggta
    21661 attagctggc agtggttaac ccagggcgac attgaccaac aaacaaaagg cgcgcttgcc
    21721 agcctgctgt tgatgctgtt actcgccgcc tacgttttgc tgagctatct gctatggcgc
    21781 agctggcggc gcactattcc ccgcgtagat ggcgttcgca agcctgccac gcctttattg
    21841 ccgggcaata cgctggcgat ttttttaccc ttaaccggtg tgctgtgtgt ggttctgctg
    21901 gcgatcctcg cggatcagtc gacgatcaat agtgaagcgc tcatcaacag cctgacaatg
    21961 gggctggtgg cgacattcat cgctttgctc ctgttactgc tgtggctgga atgggggcca
    22021 cagcgtcgcc agttgtggct atggttgccc attttattac ctgctctgcc actggtggcg
    22081 ggccagtaca cgctggcgct atggctgaaa ctggatggaa gctggacggc ggtggtctgg
    22141 gggcatctgc tgtgggtgat gccgtggatg ctgtttatcc tgcaacccgc ctggcagcgc
    22201 attgattcac ggttaatttt gattgcgcaa acactgggct ggtcgcgggc caaaatcttc
    22261 ttttacgtga aatgcccact catgttgcgc cctgtgctga ttgccttcgc ggtgggattt
    22321 gcagtcggta ttgcgcagta tatgccaacg ctgtggctgg gcgcggggcg ttttccgacg
    22381 ctcaccactg aggcggtggc attaagcagc ggcggcagca acggtattct cgccgcccag
    22441 gctttatggc aactgctatt accgcttatt atttttgccc tgaccgcgtt agtcgcaaaa
    22501 tgggtaggtt atgtcagaca aggactccgc taatgctctg cgtgaaaaat gtttcgctac
    22561 gtttaccaga aagccgcttg ctgacaaacg ttaactttac ggtggataaa ggtgacattg
    22621 tcacgttaat ggggccgtct ggctgtggaa aatccactct gttttcatgg atgattggtg
    22681 cactggccga acagttttct tgtacaggtg agctatggct caatgagcaa cggattgaca
    22741 tcctacccac cgcacagcgt cagattggca ttctttttca ggatgcactg ttatttgacc
    22801 agttcagtgt cgggcaaaat ttactgctgg cgctaccggc gacacttaaa gggaatgccc
    22861 gacgtaatgc cgtgaatgat gcacttgagc gttcaggcct tgagggagct ttccatcagg
    22921 atcctgccac tttgtctggc ggtcagcgag cgcgcgttgc tctactacgc gcccttctcg
    22981 cccaaccaaa agcgttactc ctggatgagc cattcagccg tcttgatgtg gctctgcgcg
    23041 ataattttcg ccagtgggtg ttcagcgaag ttcgcgccct ggcgatcccc gtcgttcagg
    23101 taacgcacga tctccaggat gttcctgctg atagttctgt tctggatatg gcgcagtggt
    23161 cagaaaatta caacaaactg cgataacgca aagtttttct caatgcgtca gttcagaatg
    23221 gcgcactcaa aactacaatg tcgggatttt cgatgaaacg tgtttctcaa atgaccgcgc
    23281 tggcaatggc tttagggctg gcttgcgctt cttcgtgggc cgctgaactg gcgaagcctc
    23341 ttacacttga ccagcttcaa caacaaaatg gcaaagcgat agatactcgc cccagcgcgt
    23401 tttataacgg ctggccacaa accttaaatg gcccttctgg tcatgaacct gccgccttaa
    23461 acctctctgc cagctggctt gacaaaatga gcaccgaaca gctcaacgcg tggatcaagc
    23521 aacataacct gaaaaccgat gctccggtgg cgctgtacgg taatgacaaa gatgtcgacg
    23581 ccgtcaaaac gcgactgcaa aaagcaggtt taacgcatat ctccatcctg agtgacgcgc
    23641 taagcgaacc ttcccgtctg caaaaactgc cgcattttga gcagctggtt tatccgcaat
    23701 ggctgcacga cctgcaacaa ggtaaagagg ttacggcgaa acctgccggt gactggaaag
    23761 tcattgaagc ggcctggggc gctcctaagc tttaccttat cagccatatt cccggcgctg
    23821 actacatcga taccaacgaa gtggaaagtg aaccgctgtg gaacaaagtt tctgatgaac
    23881 aactaaaagc gatgctggca aaacacggca ttcgccatga caccacggtc attctgtatg
    23941 ggcgtgacgt atacgctgca gcgcgtgtgg cgcagattat gctttatgct ggcgtgaaag
    24001 atgtgcgcct gctggatggc ggctggcaaa cctggtccga cgcgggactg cctgttgagc
    24061 gcggaacgcc accgaaagtg aaagcggaac cggatttcgg cgtgaagatc ccggcacaac
    24121 cgcagttgat gctcgatatg gaacaggccc gtggactgct gcatcgccag gatgcatcgc
    24181 tggtgagcat tcgttcgtgg ccagaattta tcggtacgac cagcggttac agctatatta
    24241 aaccaaaagg tgaaatagcc ggcgcacgtt ggggacacgc tggtagcgac tcgacgcata
    24301 tggaagattt tcataacccg gatggcacca tgcgcagcgc cgatgatatt accgctatgt
    24361 ggaaagcgtg gaatatcaaa ccagagcagc aagtttcatt ctactgcggc accggctggc
    24421 gcgcgtccga aacctttatg tacgcacgcg ccatgggttg gaagaatgtt tccgtgtatg
    24481 acggcggctg gtacgaatgg agcagcgatc caaaaaatcc ggtagcaacc ggtgaacgcg
    24541 gcccggacag tagcaaataa cattgcaatt actgacgctg gagcgacttc agcgtcagat
    24601 acccactcca cacccgcgta aaggtcgtca tccagcacaa cgcaccgaag atccacgcaa
    24661 accacgcaaa ccatgcaggg aataaacatc ccagcacaaa cagtaagatc gtttctgtgc
    24721 cttcggttaa tccccccaga tagtaaaacg acttatgtgc ataaccgggg ttatcaatct
    24781 gatgttttgc tgccagtgca gcaaaggcga gaaaactgct gcccgtgccg ataaacgcaa
    24841 acaacaacca gccgcctgcc agcgcatttt gctccggtgc agcaagaata aagccaaacg
    24901 gcaccagcgc gtaaaagaga aaatcgagag aaatatcaag aaagccgccc gcgtcggtaa
    24961 gctctctgcg ccgcgccagc gcaccgtcca gaccatcaag cagcctgttc aacaaaatga
    25021 cgactagcgc cgccagatac cagcccagcg ccagaaacgg cagagccagc acgccgatgg
    25081 caaatcccac taatgttaaa ccatctggcg taatgcccgg tttatcaaga acccgcacgc
    25141 actgatgcaa caacggttta atccggggat gaagatggcg gtctagcaca ggcactcctt
    25201 aaatataaag cctttctgat tgagcaacag tgcggatatt atggcatttt tcgcttatct
    25261 gcccgtgtgt aatttatgaa aatgattgaa gttgttgccg ccatcattga acgtgatggc
    25321 aaaattttac tcgcgcaacg ccccgcccag agcgatcagg cgggattatg ggagtttgcc
    25381 ggtggtaaag tcgagccgga tgaaagtcag cggcaggcgc tggtgcgtga gttacgcgaa
    25441 gaactgggca tcgaagcaac tgtgggtgaa tatgttgcca gccatcagcg agaagtttcg
    25501 gggcggatta tccatcttca tgcctggcac gtacccgact tccacgggac gttacaggca
    25561 catgaacatc aggcgctggt ctggtgctca cctgaagagg cgctgcaata tccgctggcc
    25621 cctgctgaca ttccattatt agaggcgttt atggctttac gcgccgccag accagaggat
    25681 tagtgctaag ggttttgtca tcacgctggc attgcagcag tattccttcg gctttaatta
    25741 ccgccccttc agaataattt tgatcctgat aaacgcagca ctgagtacag ggctgcgctg
    25801 actgcccgcc tgaactgaac acttctggcg gtacgtttac ctccacgtcc ggacgataat
    25861 gcgggttagc cagtgcaatt aatggaaatg ctaatactac ggcgaacaat gctcgactca
    25921 cagggaactc cttaacgtta ttgtctctgc tactgataac ggtagccggg tggcaaaact
    25981 ttagcgtctg agttatcgca tttggttatg agattactct cgttattaat ttgctttcct
    26041 gggtcatttt tttcttgctt accgtcacat tcttgatggt atagtcgaaa actgcaaaag
    26101 cacatgacat aaacaacata agcacaatcg tattaatata taagggtttt atatctatgg
    26161 atcagacata ttctctggag tcattcctca accatgtcca aaagcgcgac ccgaatcaaa
    26221 ccgagttcgc gcaagccgtt cgtgaagtaa tgaccacact ctggcctttt cttgaacaaa
    26281 atccaaaata tcgccagatg tcattactgg agcgtctggt tgaaccggag cgcgtgatcc
    26341 agtttcgcgt ggtatgggtt gatgatcgca accagataca ggtcaaccgt gcatggcgtg
    26401 tgcagttcag ctctgccatc ggcccgtaca aaggcggtat gcgcttccat ccgtcagtta
    26461 acctttccat tctcaaattc ctcggctttg aacaaacctt caaaaatgcc ctgactactc
    26521 tgccgatggg cggtggtaaa ggcggcagcg atttcgatcc gaaaggaaaa agcgaaggtg
    26581 aagtgatgcg tttttgccag gcgctgatga ctgaactgta tcgccacctg ggcgcggata
    26641 ccgacgttcc ggcaggtgat atcggggttg gtggtcgtga agtcggcttt atggcgggga
    26701 tgatgaaaaa gctctccaac aataccgcct gcgtcttcac cggtaagggc ctttcatttg
    26761 gcggcagtct tattcgcccg gaagctaccg gctacggtct ggtttatttc acagaagcaa
    26821 tgctaaaacg ccacggtatg ggttttgaag ggatgcgcgt ttccgtttct ggctccggca
    26881 acgtcgccca gtacgctatc gaaaaagcga tggaatttgg tgctcgtgtg atcactgcgt
    26941 cagactccag cggcactgta gttgatgaaa gcggattcac gaaagagaaa ctggcacgtc
    27001 ttatcgaaat caaagccagc cgcgatggtc gagtggcaga ttacgccaaa gaatttggtc
    27061 tcgtctatct cgaaggccaa cagccgtggt ctctaccggt tgatatcgcc ctgccttgcg
    27121 ccacccagaa tgaactggat gttgacgccg cgcatcagct tatcgctaat ggcgttaaag
    27181 ccgtcgccga aggggcaaat atgccgacca ccatcgaagc gactgaactg ttccagcagg
    27241 caggcgtact atttgcaccg ggtaaagcgg ctaatgctgg tggcgtcgct acatcgggcc
    27301 tggaaatggc acaaaacgct gcgcgcctgg gctggaaagc cgagaaagtt gacgcacgtt
    27361 tgcatcacat catgctggat atccaccatg cctgtgttga gcatggtggt gaaggtgagc
    27421 aaaccaacta cgtgcagggc gcgaacattg ccggttttgt gaaggttgcc gatgcgatgc
    27481 tggcgcaggg tgtgatttaa gttgtaaatg cctgatggcg ctacgcttat caggcctaca
    27541 aatgggcaca attcattgca gttacgctct aatgtaggcc gggcaagcgc agcgcccccg
    27601 gcaaaatttc aggcgtttat gagtatttaa cggatgatgc tccccacgga acatttctta
    27661 tgggccaacg gcatttctta ctgtagtgct cccaaaactg cttgtcgtaa cgataacacg
    27721 cttcaagttc agcatccgtt aactttctgc gatagcagca gatatgccag taaagaaatc
    27781 ccatttgact atttttttga taatcttctt cgctttcgaa caactcgtgc acctttcgag
    27841 aagcaagcat tatataatgc caggccagtt cttcttcaat tgtcccgttt tgaaaagctg
    27901 tgcttgatat cgagatcatc catgataatt ccgccgccca tattagcttc gccgaggatt
    27961 taccggagct atgattagcg caatcagaga tatagtctga gggaaaaaca gcaaatttat
    28021 tcaacaaggc gataacctgc
//
LOCUS       DACAOP010000056        27078 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.056, whole genome shotgun sequence.
ACCESSION   DACAOP010000056 DACAOP010000000
VERSION     DACAOP010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27078
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.056"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(42..1265)
                     /locus_tag="IT892_002710"
     CDS             complement(42..1265)
                     /locus_tag="IT892_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135913.1"
                     /translation="MSIDFTPGIINTYHGDIYNCTTNTDNAKTPDTPKWPCDNWEEQQ
                     PINSTFSGEGYISDQYDLAQHQLQQINACHTNTTYTNADYSKVVAQLVSLITNIETIS
                     STQLTQQTQSILNQINNIRYEKNKSAECRIIVIANPKPDKAIITKISVEEGIPITFSV
                     QTMFSDTNFIAEQRADLPTNIKDIQSLYQKMTKLYIEHSENKNRMKVFAGTNFIDFNM
                     TGQNLSGFVLTLSRFYFEDLLNINFTDANLGDTIFLHKEHPTPKLYKDGQYLDKQIEG
                     LFSTLLTINDNLLRAKAEIASTIIKFLEARITNLSYNDILKYQQEFQKQCYKQVKAFT
                     TLSRYNKIQTWAEMSEYQFEVFQYETLNPKKMSHTPYLKRPLPNEKDINYGVEIEIPS
                     GKRIRLSNHYQNIIP"
     gene            complement(1894..2319)
                     /gene="arsC"
                     /locus_tag="IT892_002711"
     CDS             complement(1894..2319)
                     /gene="arsC"
                     /locus_tag="IT892_002711"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-dependent arsenate reductase"
                     /protein_id="HAP3135914.1"
                     /translation="MSNITIYHNPACGTSRNTLEMIRNSGTEPTIIHYLETPPTRDEL
                     VKLIADMGISVRALLRKNVEPYEELGLAEDKFTDDRLIDFMLQHPILINRPIVVTPLG
                     TRLCRPSEVVLEILPDAQKGAFSKEDGEKVVDEAGKRLK"
     gene            complement(2332..3621)
                     /gene="arsB"
                     /locus_tag="IT892_002712"
     CDS             complement(2332..3621)
                     /gene="arsB"
                     /locus_tag="IT892_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenite/antimonite:H(+) antiporter ArsB"
                     /protein_id="HAP3135915.1"
                     /translation="MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPG
                     DIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLG
                     AAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
                     NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAI
                     KDPATFKTGWVVLLLLLVGFFVLEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLR
                     GAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSI
                     MNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQ
                     KNMTISWGYYFRTGIIMTLPVLFVTLAALALRLSFTL"
     gene            complement(3675..4028)
                     /gene="arsR"
                     /locus_tag="IT892_002713"
     CDS             complement(3675..4028)
                     /gene="arsR"
                     /locus_tag="IT892_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /protein_id="HAP3135916.1"
                     /translation="MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQ
                     PKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAKIIDEAWRCEQEKVQAIVRN
                     LARQNCSGDSKNICS"
     gene            4768..4851
                     /locus_tag="IT892_002714"
     CDS             4768..4851
                     /locus_tag="IT892_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Damage inducible protein"
                     /protein_id="HAP3135917.1"
                     /translation="MIDKAIIVLGALIALLELIRFLLQLLN"
     gene            complement(4905..6257)
                     /gene="gorA"
                     /locus_tag="IT892_002715"
     CDS             complement(4905..6257)
                     /gene="gorA"
                     /locus_tag="IT892_002715"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAP3135918.1"
                     /translation="MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVN
                     VGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENV
                     LGKNNVDVIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGF
                     FALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVM
                     NAEGPQLHTNAIPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPANDNINLEAAG
                     VKTNEKGYIVVDKYQNTNIEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHL
                     DYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMK
                     LVCVGSEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR
                     "
     gene            complement(6329..7171)
                     /locus_tag="IT892_002716"
     CDS             complement(6329..7171)
                     /locus_tag="IT892_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase
                     RlmJ"
                     /protein_id="HAP3135919.1"
                     /translation="MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAG
                     AGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPL
                     IARLLLREQDSLQLTELHPSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPVSRRGL
                     ILIDPPYEMKTDYQAVVSGIAEGYKRFATGIYALWYPVVLRQQIKRMIHDLEATGIRK
                     ILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSW
                     IVPE"
     gene            7374..9416
                     /gene="prlC"
                     /locus_tag="IT892_002717"
     CDS             7374..9416
                     /gene="prlC"
                     /locus_tag="IT892_002717"
                     /EC_number="3.4.24.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="HAP3135920.1"
                     /translation="MTNPLLTPFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQG
                     APYTWENLCQPLAEVDDVLGRIFSPVSHLNSVKNSPELREAYEQTLPLLSEYSTWVGQ
                     HEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLS
                     ELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEGYLLTLDIPS
                     YLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFE
                     NYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVDELQPWDI
                     AYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERKDVDVWHPDVR
                     FFELYDENNELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNR
                     PVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENW
                     CWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFR
                     PDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADA
                     FSRFEEEGIFNRETGQSFLDNILSRGGSEEPMDLFKRFRGREPQLDAMLEHYGIKG"
     gene            9424..10176
                     /gene="rsmJ"
                     /locus_tag="IT892_002718"
     CDS             9424..10176
                     /gene="rsmJ"
                     /locus_tag="IT892_002718"
                     /EC_number="2.1.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1516)-N(2))-methyltransferase
                     RsmJ"
                     /protein_id="HAP3135921.1"
                     /translation="MKICLIDETGTGDGALSVLAARWGLGHDEDNLMALVLTPEHLEL
                     RKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRD
                     AFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTD
                     ITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVK
                     RPDYAPPLANVATPNAVVTKGHRFDIYAGTPV"
     gene            complement(10225..11694)
                     /gene="dtpB"
                     /locus_tag="IT892_002719"
     CDS             complement(10225..11694)
                     /gene="dtpB"
                     /locus_tag="IT892_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpB"
                     /protein_id="HAP3135922.1"
                     /translation="MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQ
                     LGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTIVLGALVLAIGYFMTGMSL
                     LKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLIAL
                     SLAPVIADRFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFRPMSFSKLLYVL
                     LGSVVMIFVCAWLMHNVEVANLVLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLML
                     EAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPFWVVLASPILAGIYT
                     HLGNKGKDLSMPMKFTLGMFMCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLG
                     ELFISALGLAMIAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPDNITDPLET
                     LPVYTNVFGKIGLVTLGVAVVMLLMVPWLKRMIATPESH"
     gene            complement(12011..12445)
                     /gene="uspA"
                     /locus_tag="IT892_002720"
     CDS             complement(12011..12445)
                     /gene="uspA"
                     /locus_tag="IT892_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HAP3135923.1"
                     /translation="MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYS
                     DLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKY
                     DMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE"
     gene            12836..13171
                     /gene="uspB"
                     /locus_tag="IT892_002721"
     CDS             12836..13171
                     /gene="uspB"
                     /locus_tag="IT892_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspB"
                     /protein_id="HAP3135924.1"
                     /translation="MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYV
                     DGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVV
                     SLIALMIWH"
     gene            complement(13415..14914)
                     /gene="pitA"
                     /locus_tag="IT892_002722"
     CDS             complement(13415..14914)
                     /gene="pitA"
                     /locus_tag="IT892_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitA"
                     /protein_id="HAP3135925.1"
                     /translation="MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLL
                     AAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLI
                     VSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSA
                     IGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQ
                     HPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKGMLTTDVESYDKLSL
                     DQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVL
                     SSSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAVLLSGGLYWLSLQFL"
     gene            15146..16348
                     /locus_tag="IT892_002723"
     CDS             15146..16348
                     /locus_tag="IT892_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP3135926.1"
                     /translation="MERFDAIIIGAGAAGMFCSALAGQAGRRVLLIDNGKKPGRKILM
                     SGGGRCNFTNLYVEPGAYLSQNPHFCKSALARFTQWDFIDLVNKHGIAWHEKTLGQLF
                     CDDSAQQIVDMLVDECEKGNVTFRLRSEVLSVAKDETGFTLDLNGMTVGCEKLVIATG
                     GLSMPGLGASPFGYKIAEQFGLNVLPTRAGLVPFTLHKPLLEELQVLAGVAVPSVITA
                     ENGTVFRENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFLNEQRNAHPN
                     QSLKNTLAVHLPKRLVERLQQLGQIPDVSLKQLNVRDQQALISTLTDWRVQPNGTEGY
                     RTAEVTLGGVDTNELSSRTMEARKVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQ
                     DLIAAKSS"
     gene            complement(16663..17715)
                     /locus_tag="IT892_002724"
     CDS             complement(16663..17715)
                     /locus_tag="IT892_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2776 domain-containing protein"
                     /protein_id="HAP3135927.1"
                     /translation="MNIYIGWLFKLIPLIMGLICIALGGFVLESSGQSEYFVAGHVLI
                     SLAAICLALFTTAFIIISQLTRGVNTFYNTLFPIIGYAGSIITMIWGWALLAGNDVMA
                     DEFVAGHVIFGVGMIAACVSTVAASSGHFLLIPKNAAGSKSDGTPVQAYSSLIGNCLI
                     AVPVLLTLLGFIWSITLLRSADITPHYVAGHVLLGLTAICACLIGLVATIVHQTRNTF
                     STKEHWLWCYWVIFLGSITVLQGIYVLVSSDASARLAPGIILICLGMICYSIFSKVWL
                     LALVWRRTCSLANRIPMIPVFTCLFCLFLASFLAEMAQTDMGYFIPSRVLVGLGAVCF
                     TLFSIVSILEAGSAKK"
     gene            18098..19705
                     /locus_tag="IT892_002725"
     CDS             18098..19705
                     /locus_tag="IT892_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
                     /protein_id="HAP3135928.1"
                     /translation="MKAIDNQIRNISSSHQDKHSDKVNSHQHHGKVDKTHRAKIVEFD
                     KLDNDSQIDNDFGLHIIYFLQHGHWKVNDRSHQMEKVWFYNSEPSIDIQEYNRFADNT
                     TDTFIFTIIPDNNHVLKLSSPITVTVECKGGYYFINSSGDKSDIIYKVDGLSIIARNF
                     FTLLSGNFKPDWRWDVSKETFTKEKFDSYVKSVFSKIDFYKQCGVINPQNANTAYFGD
                     TDGRVGAVLYALLVSGHIGIREKGWSLLCELLKHEEMASSAYKHKNNKVLYDLLNTRD
                     MILNELHQHVFLKDDAITPCIFLGDHTGDRFSTIFGDKYILTLLNSMRNMEGNKDSRI
                     NKNVVVLAGNHEINFNGNYTARLANHKLSAGDTYNLIKTLDVCNYDSERQVLTSHHGI
                     IRDEEKKCYCLGALQVPFNQMKNPTDPEELANIFNKKHKEHMDDPLFHLIRSNTLKPT
                     PVYANYFDNTTDFRPARERIFICGETLKGEDPSKYIRQKYGHHGPGVDHNQQFDNGIM
                     GLNSLKEARDKNNKIIYSSGLSCFQPH"
     gene            19967..21589
                     /locus_tag="IT892_002726"
     CDS             19967..21589
                     /locus_tag="IT892_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
                     /protein_id="HAP3135929.1"
                     /translation="MKIGTVAGTNDSTTTIATNDMVQEHVTNFTKELFGYIANGIGDD
                     ISSIARTMLGEVVEKIDDWQIERFQQSIQDDKISFTIQTDHSEKYSMLSGMRAHILRR
                     NNNYQFIVTINSKNYGCSLDNTDVNWCSIVYLLNNMTVNDNANDVAVTESYKPIWNWK
                     ISQYNVSDIKFETMIKPQFADRIYFSNCLPVDPTSTRPTYFGDTDGSVGAVLFALFAT
                     GHLGIMAEGENFLSQLLNIEDEVLNVLLRENFNEQLNTNVNTIISILNRRDIILESLQ
                     PYLVINKDAVTPCTFLGDQTGDRFSNICGDQFIIDLLKRIMSINENVHVLAGNHETNC
                     NGNYMQNFTRMKPLDEDTYSGIKDYPVCFYDPKYKIMANHHGITFDDQRKRYIIGPIT
                     VSIDEMTNALDPVELAAIINKKHHAIINGKKFKTSRAISCRSFNRYFSVSTDYRPKLE
                     ALLACSQMLGINQVVAHNGNGGRERIGETGTVLGLNARDSKHAGRMFSMHNCQINPGA
                     GPEITTPWKSYQHEKNRNGLMPLIRRRTMLQL"
     gene            21955..23022
                     /locus_tag="IT892_002727"
     CDS             21955..23022
                     /locus_tag="IT892_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAP3135930.1"
                     /translation="MDKSKRHLAWWVVGLLAVAAIVVWWLLRPAGVPEGFAVSNGRIE
                     ATEVDIASKIAGRIDTILVKEGQFVREGEVLAKMDTRVLQEQRLEAIAQIKEAQSAVA
                     AAQALLEQRQSETRAAQSLVNQRQAELDSVAKRHTRSRSLAQRGAISAQQLDDDRAAA
                     ESARAALESAKAQVSASKAAIEAARTNIIQAQTRVEAAQATERRIAADIDDSELKAPR
                     DGRVQYRVAEPGEVLAAGGRVLNMVDLSDVYMTFFLPTEQAGTLKLGGEARLILDAAP
                     DLRIPATISFVASVAQFTPKTVETSDERLKLMFRVKARIPPELLQQHLEYVKTGLPGV
                     AWVRVNEELPWPDDLVVRLPQ"
     gene            23019..25754
                     /gene="rbbA"
                     /locus_tag="IT892_002728"
     CDS             23019..25754
                     /gene="rbbA"
                     /locus_tag="IT892_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HAP3135931.1"
                     /translation="MTHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLI
                     GPDGVGKSSLLSLISGARVIEQGNVMVLGGDMRDPKHRRDVCPRIAWMPQGLGKNLYH
                     TLSVYENVDFFARLFGHDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCC
                     ALIHDPELLILDEPTTGVDPLSRSQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWL
                     VAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQRQAHQAVVIPPYQPENAEIA
                     IEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAW
                     LFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMS
                     ERFKLNDVEDILPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLM
                     VDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFI
                     AYLQEAAGQSNEAEAPPVVHDTTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALM
                     GTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDEL
                     DRRMRAGDITVAIEIPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWL
                     QDVASRQSTPASQSGLMNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVR
                     EKELGSIINLYVTPTTRSEFLLGKQLPYIALGMLNFFLLCGLSVFVFGVPHKGSFLTL
                     TLAALLYIIIATGMGLLISTFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGR
                     WIGEVYPTSHFLTIARGTFSKALDLTDLWQLFIPLLIAIPLVMGLSILLLKKQEG"
     gene            25754..26878
                     /locus_tag="IT892_002729"
     CDS             25754..26878
                     /locus_tag="IT892_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HAP3135932.1"
                     /translation="MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTP
                     GSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIP
                     PNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVS
                     LETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPF
                     EIMMAKIWSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIF
                     MGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAI
                     LYRGAGFEIVWPQFLTLMAIGGAFFTIALLRFRKTIGTMA"
BASE COUNT         7077 a         6424 c         6817 g         6760 t
ORIGIN      
        1 tctattttta ttcaatgatt ataaagtgct aataatcaat attatggtat tatattctgg
       61 taatgatttg ataagcgaat tcttttacca gatggtattt ctatttccac cccataattt
      121 atatcttttt cattaggcag tggcctcttt aaataaggcg tgtgtgacat tttttttggg
      181 ttaagcgtct cgtattgaaa tacttcgaat tgatattcag acatttctgc ccatgtttga
      241 attttattgt atcgggagag tgtcgtaaag gctttaactt gcttataaca ttgtttttgg
      301 aattcttgct gatattttaa tatgtcattg tatgaaagat tggttatcct ggcctctaaa
      361 aatttaatta ttgtcgaagc aatttccgct tttgctcgta aaaggttgtc attaatggtt
      421 aataatgttg aaaataaacc ttcgatttgt ttgtcaagat attgtccatc tttatataat
      481 ttgggggtag ggtgttcttt atgtaaaaaa atagtgtcac ctaaatttgc gtcagtgaaa
      541 tttatattaa gtagatcttc gaaataaaac cttgacaagg ttagaacgaa cccggacagg
      601 ttctgtcctg tcatattgaa atcaataaag ttggttccgg caaagacttt catcctgttt
      661 ttattttcac tgtgctcaat atataacttc gtcatttttt gatacaggct ttgaatatct
      721 tttatattag ttggtaagtc agctcgttgt tcagcaataa aattagtatc tgaaaacatg
      781 gtttggacac tgaatgttat gggtattccc tcttctacgc taattttagt tatgattgcc
      841 ttgtcgggtt taggattagc gataacaatg attcgacatt cagcactttt gtttttttca
      901 tatctaatgt tattaatctg attaagtatt gattgtgtct gttgcgtaag ttgtgtcgaa
      961 cttatcgttt caatgttagt aataagactt acaagttgag ccacaacttt tgagtagtct
     1021 gcatttgtat atgtagtgtt cgtgtggcac gcattaattt gttgaagttg gtgttgcgct
     1081 aaatcatatt gatcagagat atatccttct ccagagaatg tggaattaat gggttgttgt
     1141 tcttcccaat tatcgcaagg ccacttcggt gtgtctggcg ttttagcatt atcggtattt
     1201 gttgtgcagt tataaatatc gccgtgatat gtatttatta tacctggggt aaagtcaatt
     1261 gacataaaat tccttattca tcatttgttt tatgctaaga tgtttaaatt ggataattag
     1321 aacaggaatg gattttcttc tacacacaat aaatgtaatg cgttatatct tcctgatata
     1381 attacctttg atttcccttt tatctccacc cggtaatatt tgtgtgtaaa aaaagggtag
     1441 tgatagtatc gtaaaggaaa tcgttaacaa ctatcaaaat gcgctcattt taaaaagtta
     1501 ttatgttctc tgatagtgtg tgaagtgatt ttttttgtga tgttttagat gtgtaataat
     1561 aaaatgggtt aaggtatctt ataattattt aataatttgt tgtgtaaacc actgataaat
     1621 cataatccag tacgtcttta aactactgcg ctgtatcgct gataactaag cagctcactg
     1681 atacaccatg ctggacgcga taattggaat ctcacgcagg gagtactgtg taaatagcaa
     1741 aatcgcctga tgcgctacgc ctgtcaggcc tacaaataac atactattca tcgaattttc
     1801 ataactttgt aggtcggata agacgcgcca gcgtcgcatc cgacataaat aaagcgcact
     1861 tttctaacaa cctgtggggg ggatatcgcc gctttatttc aggcgcttac ccgcttcatc
     1921 aaccactttc tcgccatctt ccttggagaa tgcgcctttt tgcgcatctg gcagaatttc
     1981 cagcaccact tctgaagggc ggcacaggcg agttcccagc ggcgtcacca caatcgggcg
     2041 attaatcaga atcgggtgct gaagcataaa gtcgattaac cgatcgtcag taaatttatc
     2101 ttccgcaagg cccagctcct catacggttc gacgttttta cgcagcagcg cgcgtacgga
     2161 aatccccata tcggcaatga gtttgaccag ttcatcgcgc gttggcggag tttccagata
     2221 atggataatg gtcggttctg tgccgctgtt gcggatcatc tccagcgtat tacgcgacgt
     2281 gccgcaggcc gggttgtgat aaatggtaat gttgctcata tcagtatctc attacaaagt
     2341 gaaagagaga cgtagcgcca gcgcagccag cgtcacaaac agcacaggca gggtcatgat
     2401 aatccctgta cggaagtaat atccccagct gatagtcata ttcttctgcg aaagtacgtg
     2461 cagccagagt agcgtagcca ggctaccaat tggggtaatt ttcggtccca aatcgcagcc
     2521 aatcacattg gcataaacca tcgcttcttt gataacgcca gatgccgtgc tgccatcaat
     2581 ggacaacgcg ccaaccagta ccgtcggcat attgttcata atagaagaga ggaaggcggt
     2641 gaggaatccg gtgccgagcg tcgcggccca caggccgtta tccgccagca cgttgagtac
     2701 gccagaaaga tattccgtta atccggcatt gcgcaggcca taaaccacca gatacatgcc
     2761 gagcgagaag atgacaatct gccagggggc accgcgcagg actttacccg tattaatcgc
     2821 atgaccgcgt ttagcgacga caaataatat cagcgcgccc acagctgcaa tggcgctcac
     2881 cggaatgccg agcggttcca ggacgaaaaa tcccaccagc agaagcagta aaacaaccca
     2941 gccagttttg aacgtagcag gatctttgat cgcttctgcg ggagatttca gcagcgccat
     3001 atcgtagttc tgcggaatat ctttgcgaaa atagagatgt aacatcacca gcgtggcaac
     3061 aatcgcggcg atatccaccg gcaccatcac cgaggcgtat tcgcgaaagc cgaggccaaa
     3121 gaaatcagcg gaaacgatat tcaccaggtt ggagacaata agcggcaggc tggcggtatc
     3181 ggcaatgaat ccggccgcca tcacgaacgc cagcgtagtg cctttactga accctaaagc
     3241 cagcagcatg gcgatgacaa tcggtgtcaa aataagcgcc gcgccatcat tggcaaacag
     3301 ggcggcaacg gcagcaccga gcaggacaat ccaggtaaac agcaagcgac cacgaccatt
     3361 accccagcgt gagacgtgca gcgccgccca ttcaaaaaag ccggactcat ccagcagcag
     3421 gctgatgata atgacggcga taaacgcagc cgtcgcgttc cagacgatat tccacaccac
     3481 cggaatatca cccggatgga ccacgcccgt aactaacgcc agtactgcgc cgagcgttgc
     3541 actccagccg atgcctaaac ctttcggctg ccagataacc aatacgatgg tcaggacaaa
     3601 gatagcgcct gccagtaaca taatgcctcc cggataaaac acatctgaaa attcatatgt
     3661 gtttagctaa atttttaact gcaaatgttc ttactgtccc cggaacagtt ttgtcgagcc
     3721 aggttgcgga caatcgcctg aaccttttcc tgttcacatc gccaggcctc atcaataatt
     3781 ttcgccgccc atgctggaat atgcggtgat aagcggtaat gaacccactt accttgcttg
     3841 cggtccagca atagcccgct ttcacgcagc aatgccaggt ggcgggagat cttgggctgc
     3901 gactggtcga gagcagtgca gagatcgcag acgcataact ctcccagttc gctgagcagt
     3961 aaaacgatgc ccagacgggt ttcatcagca agaattttga acaattggat gggtaacaga
     4021 aatgacatat tgcgctcctg attgttgcag gtagtgtctc tcttcgaagc ggataagtca
     4081 aaaacatata tgacttaacg aatgtgtaag tgcagaggaa ggtaataggt gtgaattttg
     4141 agttggctat tcatttgaaa ggaggtctga atcaggacgt aaaaaaaccg actttgcgtc
     4201 ggttttttac tttccagccc tgagttggtg gctctggctg gagtgagaga gttcttatct
     4261 aacagctcaa tactattagc cagtggctaa cattgcaaga attagcgatt tcttcagctg
     4321 gcggagggag cacttcggta tatatcgcag tgacgattta tatactttca ctgggtcatc
     4381 gtcatattaa gccttgtccg aatccggatg taaaaaaacc gactttgcgt cggtttttta
     4441 ctttccagcc ctgagttggt ggctctgact ggagtgagat agccatcatc taacgcatca
     4501 atgctaatac catactgaaa ctattgcaag gacgtgctgg ttttataacc tgcatgtact
     4561 gtatgattat ccagttagct ctgaggcatt ttcactctgg caatgcgcat aaacgctttc
     4621 aaagtcctgg tcagaagtac gggtggtgcc gttaactgat gctctggccg gagtgagaga
     4681 gttcttatct aacaatgaga catgcgccgt gacaggcagt ggatgagtaa gcggatgcat
     4741 tctcactcca tcgcatggag aaaacgggtg attgataaag caatcatcgt tctaggggcg
     4801 ttaattgcgc tgctggaact gatccgcttt ctgcttcagc ttctgaactg atagcggaaa
     4861 cgtaattaag ggctaagagc acactactct tagcccttta acatttaacg cattgtcacg
     4921 aactcttctg ccgccgttgg gtgaatggcg acggtattgt cgaagtcttt tttggttgcc
     4981 cccatcttca gcgccaccgc gaagccctgc aacatttcgt ccataccaaa gccaatgccg
     5041 tgaataccga caatcttctc ttccgatcca acgcacacca gcttcatgcg gcacggctgg
     5101 cggtgagtgg tgacggcggt atacatcgcg gtgaaagagg atttatacac tttcacctga
     5161 tcgtcgccat actgctcgcg cgcctgcggt tccgttaaac caacagtacc aatcggcgga
     5221 tggctgaaga ccacggtcgg aatgttgctg taatccagat gctcatccgg cttgttatta
     5281 aacaggcgtt cagagagacg gcgacccgct gcaactgcca ccggtgtcag ctccactgca
     5341 cccgtgttat cgcccaccgc gtaaatacct tcaatattgg tgttttgata tttatcgacg
     5401 acgatatagc ctttttcgtt agttttaacg ccagcggctt ccaggttgat gttgtcattg
     5461 gcaggctcgc gaccaatcgc ccaaatcagg caatccaccg tttcactgcg accatcttcc
     5521 agctccagcg tcaggctacc atcggcattt ttcactaccg ctttcgggat ggcgttggtg
     5581 tgcagctgcg ggccttcggc gttcatcact tcgaccagcg tttcggaaat catcgggtcg
     5641 aagctgcgca gcggcgcatg tttacgcaca aacagatgcg ttttcgcgcc gaggccgtta
     5701 atcacgcccg ccagctcaac ggcgatgtaa cccgcgccaa caaccgccac gcgctctggc
     5761 aaagcaggaa gggcgaagaa gccatcagaa tcaataccgt attccacgcc cggaatatcc
     5821 gggtggctcg gacgaccgcc tgtggcgatc agaatatgat cggccgtgat ggtttcgccg
     5881 tttacctcca gcgttttggc atcaacgaag cgggcaaagc ctttgattac atcaacgtta
     5941 tttttaccga gcacgttttc ataggaagta tgaatacggt cgatataggc ggtacggctg
     6001 gcgatcaacg tttcccagtt gaatttattg atagtggtat caaaaccata atccgggccg
     6061 tacatatgga tcgcttcacg gatttgcgcc gcgtgccaca tcactttttt cggcacacag
     6121 ccaacattta cgcaggtgcc gcccagctct ttggcttcaa tcagcgcaca tttctggccg
     6181 tacatagccg cgcggttgat ggaggcgata ccgccgctgc cgccgccgat ggcgatgtaa
     6241 tcatagtgtt tagtcatgac aaagtgtcct tatcgttgat taccgcgatt gtagcgcgag
     6301 acgtaatagg tgccagcaat ggctgcaatt actccggcac gatccagctt acggtggcgt
     6361 gcccggtgcc tgccggaacc agtttgctgt gcagccacgg cagcacgtta ttcatctgtt
     6421 gttccagttt ccacggcggg ttaatcacaa tcatgccgga agcggtcatg ccacggcgat
     6481 cgctgtctgg cagtaccgcc agttcaattt gcagaatttt gcgaataccg gtcgcttcca
     6541 gatcgtggat catgcgctta atttgctgac gcagcaccac cggataccac agtgcgtaaa
     6601 taccagtggc gaaacgtttg taaccttctg ctatcccgct gaccaccgct tgatagtcag
     6661 ttttcatttc atacggcggg tcgataagga ttaaaccacg gcgggaaacc ggcggcagtt
     6721 tggccttaag ctgctggaaa ccgtcggctt tttcgacacg cgcacggcta tctttctgaa
     6781 attcagaacg caacaacggg taatcgctcg ggtgcagttc ggtcagttgc aggctgtcct
     6841 gttcacgcag tagcaggcga gcaatcaacg gcgaaccggg gtagtaacgc aactgaccgc
     6901 tacggttgaa gtgttttacc acattgatgt acgcctccag ttctgcgggc aaatcgtcct
     6961 gctgccagat acgggcgatg ccttcgagat attcgccggt acgctcggca tgttcgctgc
     7021 ctaactgata acgcccggcc cctgcgtggg tgtcgagata gagaaacggt ttatctttct
     7081 ctttcagcga ctcgatgatc aggctctgaa cggtatgttt aaggacgtcg gcgtggttgc
     7141 cagcgtgaaa gctgtggcga taactgagca tgggtaaagg tgttccggta agtaaaaatc
     7201 ggcccgtatt cggggcgcac aaaagcgtat caggacagta taccgaaaag aggccgccgc
     7261 cgcgaaagcg taacgtttct cattgaaatt cactacactt aaccccatgc tacacacatt
     7321 atgtaaagcg cctgttgagc gcttccttaa cctctttaac caggactgcg cgaatgacga
     7381 atccgttact gactcccttt gaattgcctc cgttttctaa aattctcccg gaacatgtcg
     7441 ttccagccgt gactaaggca ttgaacgact gccgcgaaaa cgtggagcgc gtagtagcgc
     7501 aaggggcacc gtacacctgg gaaaatctct gccagccgct ggcggaagtg gacgatgtgt
     7561 tggggcgtat cttctccccg gtcagccacc tgaactcggt gaaaaatagc ccggaactgc
     7621 gtgaagccta cgaacaaacc ctgccgctgc tgtcggaata cagcacctgg gtagggcaac
     7681 atgaagggct gtataaagcg tatcgcgacc tgcgcgatgg cgatcattac gccacgctga
     7741 acacggcgca gaagaaagcg gttgataacg cactgcgcga ctttgaactc tctggcatag
     7801 gtctgccgaa agagaaacag cagcgttacg gcgaaattgc gacccgtctt tctgaactgg
     7861 gcaaccagta cagcaacaac gtcctcgatg cgacaatggg ctggaccaaa ctcgttaccg
     7921 acgaagcgga gctggcgggg atgccagaaa gcgcgctggc tgcggcaaaa gcccaggccg
     7981 aagcgaaaga gctggaaggt tatttgctga cgctggatat cccaagctac ttgccggtaa
     8041 tgacctactg cgacaaccag gctctgcgtg aagagatgta tcgcgcttac agcacccgcg
     8101 cctccgatca aggcccaaac gccggtaaat gggataacag caaggtgatg gaagagatcc
     8161 tcgcgctgcg tcacgaactg gcgcaactgc tgggctttga aaactacgcc tttaaatccc
     8221 ttgccactaa aatggcagaa aacccgcagc aggtgctgga tttcttaacc gatctggcaa
     8281 aacgcgcgcg tccacaaggc gaaaaagagc tggcgcaatt gcgtgccttt gccaaagccg
     8341 aatttggcgt cgatgagttg cagccgtggg atatcgctta ctacagcgaa aaacaaaaac
     8401 agcacctcta cagcatcagt gacgaacagc tgcgtccgta cttcccggaa aacaaagcgg
     8461 ttaacggcct gtttgaagtg gttaagcgta tttacggcat caccgctaaa gagcgtaaag
     8521 atgttgatgt ctggcatccg gatgtacgtt tcttcgaact gtatgacgaa aataacgaac
     8581 tgcgcggtag cttctacctc gatctgtatg cccgtgaaaa caagcgcggc ggggcgtgga
     8641 tggatgactg cgtaggccag atgcgtaaag ctgatggttc tttgcaaaaa ccggtcgcgt
     8701 atttgacttg taacttcaac cgcccggtaa atggtaaacc ggcgctgttc actcacgacg
     8761 aagtgatcac cctcttccac gagttcggtc acggcctgca ccatatgctg acccgcatcg
     8821 aaaccgctgg tgtttccggt atcagcggtg tgccgtggga tgcggtcgaa ctgccgagtc
     8881 agtttatgga aaactggtgc tgggagccgg aggcgctggc gtttatctct ggtcactatg
     8941 aaaccggcga accgctgccg aaagagttgc tggataaaat gctggcggcg aagaactacc
     9001 aggcggcgct gtttattctg cgtcagctgg agttcggcct gtttgatttc cgccttcatg
     9061 ccgagttccg cccggatcag ggggcaaaaa tcctcgaaac tctggcagaa atcaagaaac
     9121 tggttgccgt ggtgccatct ccgtcctggg gccgtttccc gcacgctttc agccatattt
     9181 tcgccggtgg ttatgccgca ggttactaca gctacctgtg ggctgacgta ctggcggcag
     9241 atgctttctc gcgctttgag gaagagggca ttttcaaccg tgaaaccggg cagtcgttcc
     9301 tcgacaacat tctgagccgt ggcggttcag aagagccgat ggatctgttc aaacgcttcc
     9361 gtggtcgtga accgcagctg gatgcgatgc tggagcatta cggcattaag ggctgatcat
     9421 tcagtgaaaa tctgcttaat tgatgaaaca ggcaccggag acggtgcctt atctgttctg
     9481 gcggcccgct gggggctggg gcacgatgaa gacaacctga tggcgctggt gttaacgccg
     9541 gaacatctgg aattgcgcaa gcgtgatgag ccaaaacttg gcggcatctt tgttgatttt
     9601 gttggcggag cgatggcgca ccgacgcaaa ttcggcggtg gtcgcggtga ggcggtggcg
     9661 aaagcggtgg gcattaaagg cgattatttg ccggatgtgg tggatgccac tgcaggactt
     9721 gggcgcgatg cctttgtact ggcttcagtc ggctgccgcg tgcggatgct ggagcgtaat
     9781 ccagtggttg ccgcgctact cgacgacggc ctggcgcgtg gttatgcgga tgcggaaatc
     9841 ggcggctggt tgcaggagcg gttgcagtta attcacgcct ccagcctgac ggcgctgact
     9901 gatattaccc cgcgcccgca ggtggtttat ctcgacccga tgttcccgca taagcagaaa
     9961 agcgcgctag tgaaaaaaga gatgcgtgtc tttcagtcgc tggtgggacc ggatcttgat
    10021 gccgatggat tactggagcc tgcacgcttg ctggcgacca aacgcgtggt ggtaaagcgc
    10081 ccggactacg cgccaccgct ggcgaatgtc gccacgccaa acgcggtagt cactaaaggg
    10141 catcgctttg atatctatgc aggtacgcca gtgtaaaact aaagcagggt agcgataacg
    10201 ctaccctgct ttctgcaaga ataattaatg gctttccggc gtcgcaatca tgcgtttcag
    10261 ccacggcacc atcaacagca tcactactgc aacgcccagc gtgaccagac caatcttacc
    10321 aaacacgttg gtatagacgg gcaacgtctc aagcggatcg gtaatgttgt ccggcaccgc
    10381 ggtaaatgtt gccacatagc cgcccagcaa gaacgcggca gcctgcgtca ggaaccacat
    10441 cccgagaata aagcccatca aatgctgcgg caccagggca gcaatcatcg ccaggccaag
    10501 ggcgctaata aacagttcac ctaagctctg gaataagtac accagcacga taaaccatgg
    10561 cgatgtcagc ccttgtgcat ccgcaaacca cattcccgca gctgccgccg tcaaaaagcc
    10621 cagtgagcac ataaacatgc cgagagtaaa tttcatcggc atcgagaggt ctttgccttt
    10681 gttacccaga tgcgtgtaaa tgcctgccag tattgggctg gcgagtacca cccagaacgg
    10741 gttaagcgcc tggaagctga ccgggttgat ggaaaaaccg agaatttcat gatgcacgtt
    10801 gttgatggca aagaagttca gcgatgttgg catctgggcg tagagaatgt aaaacaccac
    10861 cgcttcgagc atcaggacaa aggcgacaaa cattttattg cgcccggttt tatccagctt
    10921 gaatgcctga cgaaagaaga tgatggtgac gacgatggag agaacaatca gcaccagatt
    10981 ggcgacttct acgttgtgca tcagccatgc gcatacgaag atcatcacca cgctgccaag
    11041 taacacgtac aacagtttgc tgaagctcat tggccggaag tcgggttcag aaccaatgtc
    11101 tttcaccatt ccacgacagg cgatgtaaac cagtaatgcg ataattaacc ccgccccgca
    11161 cagattgtag gtgactgaat aaccgaatct atcagcgatc acaggggcca gcgataacgc
    11221 tatcaacgag ccgatgttga tcgacatata gaacagggtg aatgcgccat caagccgcgg
    11281 atctttcggc ggatagcact tcgaaagcaa gctggctggg ttagctttaa acaggccgtt
    11341 accgacagcg atagtcccca gggcgatgaa aatcaggtca ggcttaagta gcgacatgcc
    11401 ggtcatgaag tagccaatcg ccagcacaag tgctccaaga acaatggtgc gtttggtccc
    11461 cagcaggtgg tcgccgacat agccgccaat ggaaatgagg ccatagacca gcgcagcaaa
    11521 agcaccaaaa gtgacaaaag cctgctcttg cgagaatcca agctgtttaa cgaagaaaac
    11581 cgccagtacg ccctgcacgc cgtagtagcc gaatcgctcc cataactcga caaaaaagat
    11641 catgaaaaat gggcgaggtt gctgcagcat ccccatgggt gttgttgtat tcatatttat
    11701 taaccttcca ataccatcct gaaaagtatg aacgcgtaag ggataacgcg cgaaaaagtt
    11761 tacatctgtc agagattctt aatattgatg cggtgaatag attaatacac tattacaaca
    11821 gaaaataacc agatgatcac actaatgatg gaaaatatga tggtgttaaa tgttgtattg
    11881 gctggggatt ttgattgcgt acgcagaccg taggccagat aaggtgttta cgctgatcag
    11941 gtaacaaggc gcgccaaaaa gcaaaacgcc cgcatatgcg ggcgttcagg aacacgtcgt
    12001 agagggaaga ttattcttct tcgtcgcgca gcggaacaat cagcatatca acgtgaacgg
    12061 tgttgatcag ctgacgtgcg gaagacatca gtttgctcca gaagtcctgg tggtgaccac
    12121 aaaccaccaa atccatatcg tatttcttga ttgcatcgac cagaacctgg cccaggtcgc
    12181 cgctgccgct cagggtttca gtgattgggt agcctgcatt agtggaaagc tcggtcagtg
    12241 catgatgtgt ctcttcagag atgcgtttct gcatatcacc cagattcaca tcaataagcc
    12301 cggtgtatag gtcagagtag tttacatcta cgtggatcag agaaactttc gcattgtagg
    12361 ggcgagccat agagactgct ttctctacca gaactttgct ttccggggag aggtcgaccg
    12421 cgatgagaat gtgtttataa gccatagtgt tactccttcc ataaagttgt cgatgactgg
    12481 ccagctagcg tttcttgtgc cgttacgtca cccgcgtcct gcgaactacg tgcgcggggc
    12541 taacccagcc gtaaagattc agtgttaaga ccatccttac cttatagcga cccggatgat
    12601 ccgtcaatcc gccttgctta ctcgttagat aaacaaattt tcgacatgaa tatattgata
    12661 gtggttaacc ttctggaaaa aaaacaacct gatctcctac actatctata gagccgctcg
    12721 tatgttggtc accacaaaag cggtttctcc aggacctggt gttaactgat tggcagcgta
    12781 tcgggagcgg tagccccggg gtggaactcc gcgggcaggt cgccggggag gaggtatgat
    12841 aagcaccgtc gcattatttt gggctttatg tgtcgtttgc attgttaaca tggcgcgcta
    12901 tttctcatca ctacgcgcgt tgttagtggt actgcgtaac tgcgatccat tgctctatca
    12961 atatgttgat ggagggggct tttttacctc acatggccaa cccaacaaac aggtgcgtct
    13021 cgtttggtat atctatgccc aacgttatcg cgatcatcac gatgatgaat ttattcgccg
    13081 ctgtgagcgg gtgcgtcggc agtttattct gaccagcgca ttgtgtggtc tggtggtggt
    13141 cagcctgatt gcattgatga tttggcatta agcacttcag caataataac gcataaaaaa
    13201 agcgggccag taaactgacc cgctcgagac tgattacaaa cgcaaaattg cctgatgcgc
    13261 tacgcttatc aggcctacat aatctctgca atctattgaa tttgcatgtt tttgtaggcc
    13321 ggataaggcg ttcacgccgc atccggcatg aacaaagcgc actatgtcac aatctgaagc
    13381 gggccagctg acccgctcgt tttggtgcgt acgattacag gaactgcaag gagagccagt
    13441 acagcccgcc ggaaagcagt accgcagccg gaagggtaaa cacccaggcc atcagaatgc
    13501 tggtcacggt tttacgctgt aagccgccac catctaccac catcgtcccc gcgacagaag
    13561 aggagagtac gtgagtagtg gaaaccggca tcccggtata actcgccagg ccgatagaca
    13621 ctgccgccgt catctgggca gacatcccct gagcgtaggt catgcctttc ttaccgattt
    13681 tctcaccgat agtcgttgcc acacggcgcc agccaatcat cgtaccgata cctaacgcca
    13741 gcgcgaccgc catgatgatc cacaccggtg catactcgat ggtgctaagc atgtcggact
    13801 tcagtttctt caacaggcgc tgatcgtcag cactcacgcc aggcatcttc accactttgt
    13861 cgatagtgtc agaaacgcac agcataatgc ggcgcatctg gctacgttga tcaagcgaca
    13921 gcttgtcgta gctttccaca tcggtggtca acataccttt caggcggttg agcgcgttaa
    13981 tggtattcga cggatggcag tggaactccg caggttgcgt tgcgccagct tccggagccg
    14041 gtactaactg atcagcaccg gtagcctgtt tgagcagcgc aggatgctgc tcaaagtaag
    14101 cttcgacgtt gttgatggca tcacgggtac gggtgatttc gtagccagtg gcattcatgt
    14161 tcaccacgaa gcctgctggc gcgacgccaa tcaataccaa cataaccaga ccaatgcctt
    14221 tctgaccatc gttcgcgccg tgcgaaaacg ccacgccgat agcggaaagg atcagcgcaa
    14281 tacgcgtcca gaacggcggc tttttcttgc cgtctttctt ttcacgctcc gctggggtca
    14341 ggtggatacg ggcgcgtttc ttggtgccgc tccagtagcg acgcagcaag aaaatcagac
    14401 cgccagcaaa caccaggccg acaatagggg aaacgatcag agaaccgaaa atacttaata
    14461 ctttcgggat attgagtgca tccaccactg acgtcccggt catcaacgca ttggttaaac
    14521 caatcccgat gatcgcgcca atcagcgtat gagagctgga tgcaggtaaa ccaaagtacc
    14581 aggtacccag gttccagata atcgccgcca gcaacataga gaacaccatg gcaaggccat
    14641 gagacgatcc catattaagc agcagatccg tcggcagcat atgcacaatg gcataggcaa
    14701 cactcagacc acccagcaaa acacccaaaa agttgaatac cgccgccata accacggcga
    14761 gctgagaacg catcgcgcgg gtatagataa cggttgccac ggcgttggct gtgtcatgga
    14821 aaccattgat ggcttcgtag aacagcacaa aagccagtgc aagcaataat aacagcccgg
    14881 tatgcaaatc caggccagca aacaaatgta gcataggacg ttacgccatt ttgaggacat
    14941 gaacgcggcg cattatcagt gactttcgcg gcgcgggcaa agtgaaatat agactttttt
    15001 tgatttgccc cctgtatgga tttcactcaa aaaataatta tcttatataa ttcaggcaaa
    15061 tacttccttt tagtaatatt gatgctggtg cgaccactga ggaatcttta caattcacgc
    15121 ccgttttttc taagaggagc gcaacgtgga aaggtttgat gccattatta taggcgctgg
    15181 tgcggcgggt atgttctgtt ctgcgctggc aggtcaggca ggacgccggg ttctgctgat
    15241 cgataatggt aaaaaaccag ggcgcaaaat ccttatgtct ggcggtgggc gctgcaactt
    15301 taccaacctt tatgtcgaac caggcgctta tctgagccag aatccgcatt tttgtaagtc
    15361 tgcactcgca cgttttaccc agtgggattt cattgatctg gtcaataaac acggcatcgc
    15421 ctggcacgag aaaacgttag ggcaactctt ctgcgatgac tccgcgcagc agattgtcga
    15481 catgctggtg gatgagtgcg agaagggcaa tgtgaccttc agattgcgta gcgaagtgct
    15541 gagtgtggcg aaggatgaaa caggcttcac gcttgatctg aacggcatga ctgtcggttg
    15601 cgaaaagctg gtcatcgcga ctggtgggct gtcaatgccg gggctgggcg cgtcgccgtt
    15661 tggttataag attgccgaac aatttggcct caacgtgctg ccgacccgcg cgggtctggt
    15721 gccattcact ctgcataaac cgttgctcga agagttacag gtgctggcgg gcgtggcggt
    15781 gccttccgtg attaccgctg aaaacggcac cgttttccgt gagaacttac tcttcaccca
    15841 ccgcggcttg tctggaccgg cggtgttgca gatttcaagc tactggcaac cgggggaatt
    15901 tgtcagcatc aatctgctac cggatgtgga cctcgaaacc ttcctgaatg agcagcgtaa
    15961 cgcacatccg aatcaaagcc tgaaaaacac actggcggtt catctaccga agcggttggt
    16021 tgaacgctta cagcaactcg ggcaaatccc ggatgtttcg ctaaaacagc tcaacgtgcg
    16081 tgaccaacag gcactgatta gcacattgac cgactggcgc gtacaaccca acggcactga
    16141 aggctatcgc actgccgaag tgacgctcgg cggcgtggac accaacgaac tctcttcacg
    16201 gacgatggaa gcgcgcaaag tgcctgggct gtacttcatc ggcgaagtga tggacgtcac
    16261 cggctggctg gggggctata acttccagtg ggcgtggtcg agtgcgtggg cttgtgcgca
    16321 ggatttgatt gcagcaaagt cgtcctgacc tatttcctaa agatgaaaat tattagagtc
    16381 gcattaaaaa tgagctaatt ttgatagtgg ttatcttgtg attattttct aatgagcccg
    16441 tgaactgaaa ccctccatgc ttaatataag gtggatggaa aggtgattga aaactcaccc
    16501 agtggccaga tctttatgaa atatgaacag gttgaaaaaa acagtaactt tgctgttttt
    16561 tatacttaac cactatgcat taatgctgcg ttatttcatg atgcctaaga aaaaccagcg
    16621 ttacgcaaat ggtcaacgct ggttttatcc ggtacgttgc aattattttt tagcagaacc
    16681 cgcttctaat attgaaacga ttgagaacaa cgtaaagcat accgctccca aaccgaccag
    16741 aactcgcgaa ggaataaaat atcccatgtc ggtctgcgcc atttccgcaa gaaacgatgc
    16801 caggaaaagg caaaacaggc aggtgaagac gggaatcatc ggtattctgt tggctaacga
    16861 acaggtacgt ctccatacca gtgccagtag ccagactttt gagaatatgc tgtaacagat
    16921 cattccgagg caaataagaa taatgccggg agccagtcgg gcgcttgcat cggaactgac
    16981 taagacgtat atcccctgca gtaccgtgat tgagccgaga aaaataaccc aataacacca
    17041 cagccagtgt tctttagttg aaaacgtatt acgtgtttga tggacaattg tggcaacaag
    17101 gccaattaga caggcacaga ttgcggttaa cccaagcaat acgtgacccg cgacataatg
    17161 cggagttatg tcagcactac gtaacagcgt aatagaccaa atgaaaccga gcagggtgag
    17221 taaaacggga acggcaatga ggcagttacc gattaatgaa gaataagcct gtaccggtgt
    17281 tccgtcgctc ttgctccccg ctgcattttt gggaatgagc agaaagtgac cggatgacgc
    17341 tgccaccgtc gatacacagg cggcaatcat accaacgccg aaaataacat ggccggcgac
    17401 aaactcgtct gccatcacat cattgcctgc taacagtgcc caaccccata tcatggtgat
    17461 aattgacccc gcatagccaa taatggggaa caatgtattg taaaacgtat taacgccgcg
    17521 cgtgagctgc gaaatgataa taaatgcggt agtgaataat gccaggcata tggccgccag
    17581 agaaatcagc acatgacccg cgacgaaata ctcgctttgc cctgaacttt ccagcacaaa
    17641 gccacctaac gcgatacaaa ttaagcccat aatcaaaggg attaatttga aaagccaccc
    17701 gatatatatg ttcactttaa actcctcagg tatccctgct aatattgaaa tatgcattaa
    17761 tgataatttc atcctgttaa tataatgacg agatatcatt aaagacaaat gcatagcata
    17821 actatagcgg ggtttacttt gcagagcgct acttttcagc gttcaaaagg ccatgataaa
    17881 taaaaattta tcctaagatt aattcttatg ctgttgtttt ttacaattat cttccaggga
    17941 gggattattc ttcattattt ggtaaaagac cggatagtct cggtgcttaa aatcagcgaa
    18001 catataagta ttattatttt atatcgtcgt aaatctgttt ttcagacaag tatcatttat
    18061 tttgttacaa acaattcaaa aatatcacag gttatttatg aaagcaattg acaatcagat
    18121 tagaaacatc tcttcaagcc atcaagataa gcattcagat aaagttaaca gtcatcaaca
    18181 ccatggcaag gttgataaaa cacatcgtgc aaagatagtt gaatttgata aactggataa
    18241 tgattcgcaa atagataacg attttggcct gcatatcatc tatttcctgc aacatggtca
    18301 ctggaaggta aatgatcgta gtcaccagat ggagaaagta tggttttata atagtgaacc
    18361 ttctatagat attcaagaat ataatagatt cgccgacaat actactgata cgtttatctt
    18421 tacaattata ccagacaata accatgtgtt aaaattatcg tctcccatta ccgttactgt
    18481 tgagtgtaag ggcggttatt attttattaa ttcctctgga gataaatcag atataattta
    18541 taaagttgat gggctttcta tcatagcgag aaatttcttt actcttctta gtggtaattt
    18601 caaacctgac tggcgttggg atgtctctaa agagacgttt actaaggaaa agtttgatag
    18661 ctatgttaaa tctgtgtttt caaaaataga cttctataaa cagtgtggtg tgattaaccc
    18721 acaaaatgcc aacacggctt attttggcga tacagatgga agagtaggcg ctgtacttta
    18781 tgcattgctc gtttcagggc atataggcat cagggaaaag ggttggagtt tattatgtga
    18841 attattaaaa cacgaagaga tggcttcatc tgcatacaaa cataaaaata ataaagtgct
    18901 ctacgattta ttaaatacga gagacatgat cttgaatgag ttgcatcaac atgttttttt
    18961 aaaggacgat gcgataaccc cttgtatctt ccttggggat catacaggcg atagatttag
    19021 tactattttt ggtgataaat atatccttac tttgctaaat tctatgcgaa atatggaggg
    19081 taataaagat agccgtatta ataaaaatgt cgtcgttctg gctggaaatc atgaaatcaa
    19141 ttttaatggt aactatactg cacgactagc aaatcataaa ctctctgccg gtgatacgta
    19201 taacttaatt aaaacgctcg atgtttgtaa ttatgactca gaaaggcaag ttttaaccag
    19261 tcatcacgga ataataagag atgaagaaaa aaaatgttat tgtctcggtg ctttgcaggt
    19321 tccatttaat cagatgaaaa atcctactga tcctgaggaa ttagccaata tttttaataa
    19381 aaaacataaa gaacacatgg atgatcctct attccatcta atccgaagca atactttgaa
    19441 acccacacct gtatatgcta attattttga taacactact gatttcagac cagcacgtga
    19501 acgtatcttc atatgtgggg agacactcaa aggtgaagac cccagcaaat acattagaca
    19561 aaaatatggg catcatgggc ccggggtaga tcataatcaa caatttgata atggtattat
    19621 ggggctaaat tccctgaagg aagcacgtga taaaaataat aaaataattt attcctcagg
    19681 gcttagttgt tttcaaccac attaaaactc catgaatacg gtggtatgtc tttttaatcc
    19741 tgccagtatt tcataggttt tcttaatcga ttgtagaggc atgttctgat gacgcctcta
    19801 caatctttag ggactttctc tgctatgaga taagaaattt catattatgc tttgaggctg
    19861 aatgatttgt gcaaaatata attattttcc catcgaacat gaggtgtatg tcataagata
    19921 aaatgttaac tatgtattcc tcgcggtaaa taatatgagg taaaatatga aaattggaac
    19981 tgtggcaggc actaacgaca gtacaacgac aatcgcaaca aatgatatgg tgcaagagca
    20041 tgttaccaac ttcactaaag aactgtttgg gtatattgca aatggtatag gtgatgatat
    20101 atcaagtatt gccaggacaa tgctcggtga ggttgtggaa aaaatagatg attggcaaat
    20161 agaacggttc caacaatcta ttcaagatga caaaatttca tttaccatac aaacggatca
    20221 ttcagaaaaa tatagtatgc tatcgggcat gcgtgctcat attctacgta ggaataataa
    20281 ttatcagttt attgtgacaa ttaatagcaa aaattacggt tgctctcttg ataataccga
    20341 tgttaattgg tgcagtattg tttatttact taataatatg acagtaaatg ataatgctaa
    20401 tgatgttgca gttactgagt cgtacaaacc catctggaac tggaaaatat cgcaatataa
    20461 tgtatctgat attaaattcg aaacaatgat aaaaccccag ttcgctgaca gaatctattt
    20521 ctccaattgt ttacccgttg atcccacaag taccagacca acctattttg gtgataccga
    20581 tggctcagtc ggtgcagttt tgttcgcgct tttcgcaacg ggacatttgg gaatcatggc
    20641 tgaaggagaa aatttcctta gccagttgct taatatagaa gatgaagttc tcaacgtatt
    20701 gctaagggag aactttaatg agcaacttaa cactaatgtt aatacaataa tcagtatcct
    20761 gaacagaaga gacattattt tagaaagtct tcagccttat ttagttatta ataaagacgc
    20821 tgtgacgcca tgtacgtttc tgggcgacca aaccggcgat cgatttagca atatctgtgg
    20881 tgatcaattt atcatcgatt tgttaaaacg cataatgagt atcaatgaaa atgttcatgt
    20941 attagctgga aatcatgaaa cgaattgcaa tggtaactat atgcagaact tcacgcgtat
    21001 gaaaccactc gatgaggata cctactctgg gataaaagat tatcctgtat gtttctatga
    21061 ccccaaatac aaaataatgg caaatcatca tgggataact tttgatgatc agcgaaaacg
    21121 ttacattata ggaccgataa cagtctctat tgatgaaatg accaatgctc tcgatccggt
    21181 cgaattagcg gcaattatca ataaaaagca tcatgctata attaatggca aaaagtttaa
    21241 aactagccgg gctatctctt gtcgatcctt taatcgttat ttttctgttt cgacagatta
    21301 cagacctaaa cttgaagcac tattagcatg ttcacaaatg ttaggtataa atcaagttgt
    21361 tgcacataac ggaaatggtg gaagagaacg cataggcgaa acggggacag ttttaggtct
    21421 taacgcccgt gacagtaaac atgctggaag aatgttcagc atgcataatt gccaaattaa
    21481 ccctggtgca gggcctgaga taaccactcc ctggaagtct taccagcatg aaaaaaacag
    21541 aaatggactt atgcctttga ttagaaggcg cacaatgtta cagctctgaa ccatagacaa
    21601 catgaatatt aatgttacta tctggttgag actgttgata aaacgtaaaa aggaatgctc
    21661 tgttcctgca actgaacagg cgtgaaacgc tatccaacag gatggatacc gttttgtcag
    21721 ccagttttat agatcacact tatgagtatg cgtgtttcat ttacggccag gaatgctgat
    21781 gatgacaaca ttactacccg ttttcactaa gccttccccg ttggcgctca atgctctgcg
    21841 cgctggtcgt atttgccgtt tccttcttat cccggatgga agaatccgct gaacgtcgtt
    21901 cggcggcagt tgtaacacgc gtcgtttgct tacagggatt atggcgggtc gattatggat
    21961 aagagtaagc gccatctggc gtggtgggtt gtcgggttac tggcggtggc ggctatcgtg
    22021 gtgtggtggc tgttgcgccc ggcaggtgtg ccggaaggct ttgctgtcag taatgggcgc
    22081 attgaagcga cggaagtgga tattgccagc aaaattgccg ggcgtatcga caccattctg
    22141 gtgaaagaag gccagtttgt tcgcgaaggt gaagtgctgg cgaagatgga tactcgcgtg
    22201 ttgcaggaac agcgactgga agccatcgcg caaatcaaag aggcacaaag cgccgttgct
    22261 gccgcgcagg ctttgctgga gcaacgacaa agcgaaactc gtgccgcaca gtcgctggtt
    22321 aatcaacgcc aggcagaact ggactccgta gcaaaacgtc atacgcgttc ccgttcactg
    22381 gcccaacgag gggctatttc tgcgcaacag ctggatgacg atcgcgccgc cgctgagagc
    22441 gcccgagctg cgctggaatc ggcgaaagct caggtatcgg cttctaaagc ggctatagaa
    22501 gcggcacgca ccaatatcat tcaggcgcaa acccgcgtcg aagcggcaca agccactgaa
    22561 cggcgcattg ccgcagatat cgatgacagc gaactgaaag ccccgcgtga cggacgcgtg
    22621 cagtatcggg ttgccgagcc aggcgaagtg ctggcggcag gcggtcgggt gctgaatatg
    22681 gtcgatctca gcgacgtcta tatgactttc ttcctgccaa ccgaacaggc gggcacgctg
    22741 aaactgggcg gtgaagcccg gctgatcctc gatgccgcgc cagatctgcg tattcctgca
    22801 accatcagtt ttgtcgccag tgtcgcccag ttcacgccaa aaaccgtcga aaccagcgat
    22861 gaacggctga aactgatgtt ccgcgtcaaa gcgcgtatcc caccggaatt actccagcag
    22921 catctggaat atgtcaaaac cggtttgccg ggcgtagcgt gggtgcgggt gaatgaagaa
    22981 cttccgtggc ctgacgacct cgtggtgagg ttgccgcaat gacgcatctg gaactggttc
    23041 ccgtcccgcc tgtcgcgcaa ctggcgggcg tgagccagca ttatggaaaa accgttgcgc
    23101 tgaacaatat cactctcgat attccggccc gctgtatggt cgggctgatt ggcccggacg
    23161 gcgtcgggaa gtcgagcttg ttgtcgttga tttccggtgc ccgcgtcatt gaacagggca
    23221 atgtgatggt gctgggcggc gatatgcgcg acccgaagca tcgccgcgac gtctgcccgc
    23281 gcatcgcctg gatgccgcag gggctgggca aaaacctcta ccacaccttg tcggtgtatg
    23341 aaaacgtcga ttttttcgct cgcctgttcg gtcacgacaa agcggagcgg gaagtgcgaa
    23401 tcaatgagct gctgaccagc accgggttag caccgtttcg cgatcgtccg gcagggaaac
    23461 tctccggcgg gatgaagcaa aaacttgggc tgtgctgcgc gttaatccac gacccggaac
    23521 tgttgatcct tgatgagcca acaacggggg ttgacccgct ctcccgctcc cagttctggg
    23581 atctgatcga cagtattcgc cagcggcaga gcaatatgag cgtgctggtc gccaccgcct
    23641 atatggaaga ggccgaacgc ttcgactggc tggtagcgat gaatgccgga gaagtgctgg
    23701 caactggcag cgccgaagag ctacggcagc aaacgcaaag cgctacgctg gaagaagcat
    23761 ttataaatct gttaccgcaa gcgcaacgcc aggcgcatca ggcggtagtg atcccaccgt
    23821 atcaacctga aaacgcagag attgccatcg aagcgcgcga tctgaccatg cgttttggtt
    23881 ccttcgttgc cgttgatcac gttaatttcc gcattccacg cggggagatt tttggttttc
    23941 ttggttcgaa cggctgcggt aaatccacca ccatgaaaat gctcaccgga ctgctgcccg
    24001 ccagcgaagg tgaggcgtgg ctgttcgggc aaccggttga tccaaaagat atcgataccc
    24061 gccgtcgggt gggctatatg tcgcaggcgt tttcgctcta taacgaactc accgtgcggc
    24121 aaaaccttga gttacatgcc cgtttgtttc acatcccgga agcggaaatt cccgcaagag
    24181 tggctgaaat gagcgagcgt tttaagctca acgacgttga agatattctg ccggagtcat
    24241 tgccgctcgg cattcgccag cggctttcgc tggcggtggc ggtgattcat cgcccggaga
    24301 tgttaatcct cgatgagcct acttctggtg tcgatccggt ggcgagggat atgttctggc
    24361 agttgatggt cgatctctcg cgccaggaca aagtgactat cttcatctcc acccacttta
    24421 tgaacgaagc ggaacgttgc gaccgcatct cactgatgca cgccggaaaa gtgcttgcca
    24481 gcggtacacc gcaggaactg gttgagaaac gcggagccgc cagtctggaa gaggcattta
    24541 tcgcctattt gcaggaagcg gcagggcaga gcaacgaagc cgaagcgccg cccgtggtac
    24601 acgacaccac ccacgcgccg cgtcagggat ttagcctgcg ccgtctgttt agctacagcc
    24661 gccgcgaagc gctggaactg cgacgcgatc cagtacgttc gacgctggcg ctgatgggaa
    24721 cggtgatcct gatgctgata atgggttacg gcatcagtat ggatgtggaa aacctgcgct
    24781 ttgcggtgct cgaccgcgac cagaccgtca gtagccaggc gtggacactc aacctctccg
    24841 gttcccgtta ctttatcgaa cagccgccgc tcaccagtta tgacgagctt gatcgtcgga
    24901 tgcgtgcggg cgatatcacg gtggcgattg agatcccgcc caatttcggg cgcgatatcg
    24961 cgcgtggtac gcctgtggaa ctcggcgtct ggatcgacgg agcgatgccg agccgtgctg
    25021 aaacggtaaa aggttacgtg caggccatgc accagagctg gttacaggat gtggcgagcc
    25081 gacaatcgac acccgccagc caaagcgggc tgatgaatat tgagacgcgc tatcgctata
    25141 acccggacgt aaaaagcctg ccagcgattg ttccggcggt gatcccgctt ctgctgatga
    25201 tgatcccgtc aatgctaagc gcccttagcg tggtgcggga aaaagagctt gggtcgatta
    25261 tcaaccttta cgtgaccccc accacgcgta gtgaattttt gcttggtaaa cagttgccat
    25321 acatcgcgct ggggatgctg aactttttcc tgctctgcgg cctgtcggtg tttgtgtttg
    25381 gcgtaccgca taaaggcagt ttcctgacgc tcaccctggc ggcgctgctg tatatcatca
    25441 ttgccaccgg aatggggctg ctgatctcca cctttatgaa aagccagatt gccgccattt
    25501 tcggaacggc gattatcacg ttgatcccgg cgacacagtt ttccgggatg atcgatccgg
    25561 tagcttcgct ggaagggcct ggacgttgga tcggcgaggt ttacccgacc agtcattttc
    25621 tgactatcgc ccgcgggacg ttctcgaaag cgctggatct gactgatttg tggcaacttt
    25681 ttatcccgtt gctgatagcc atcccgctgg tgatgggctt aagtatcctg ctgctgaaaa
    25741 aacaggaggg atgatgcgcc atttacgcaa tatttttaat ctgggtatca aagagttgcg
    25801 cagtctgctc ggtgataaag cgatgctgac gctgattgtc ttctcgttta cggtgtcggt
    25861 gtattcgtca gcgaccgtta cgccaggatc gttgaacctc gcgccgatcg ccattgccga
    25921 tatggatcaa tcgcagttat cgaaccggat cgttaacagc ttctatcgtc cgtggttttt
    25981 gccaccggag atgatcaccg ccgatgagat ggatgccgga ctggacgccg gacgctatac
    26041 cttcgcgata aatattccgc ctaattttca gcgtgatgtc ctcgccggac gccagccgga
    26101 tattcaggtg aacgtcgatg ccacgcgcat gagccaggca tttaccggca atgggtatat
    26161 ccagaatatt atcaacggtg aagtgaacag ctttgtcgcg cgctaccgtg ataacagcga
    26221 accgttggta tcgctggaaa cccggatgcg ctttaacccg aacctcgatc ccgcgtggtt
    26281 tggcggggtg atggcgatca tcaacaacat taccatgctg gcgattgtat tgaccggatc
    26341 ggcgctgatc cgcgagcgtg aacacggcac ggtggaacac ttactggtga tgccgataac
    26401 gccgtttgag atcatgatgg cgaagatctg gtcgatgggg ctggtggtgc tggtggtatc
    26461 gggattatcg ctggtgctga tggtgaaagg tgtactgggc gtaccgattg aaggctcgat
    26521 cccgctgttt atgctgggcg tggcgctcag tctgtttgcc accacgtcaa tcggcatttt
    26581 tatggggacg atagcgcgtt caatgccgca actggggctg ctggtgattc tggtgctgct
    26641 gccgctgcaa atgctttccg gtggttccac gccgcgcgaa agtatgccgc agatggtgca
    26701 ggacattatg ctgaccatgc cgacgacaca ctttgttagc ctcgcgcagg ccatcctcta
    26761 ccggggtgcc ggattcgaaa tcgtctggcc gcagtttctg acgctgatgg caattggcgg
    26821 cgcatttttc accattgcgc tgctgcgatt caggaagacg attgggacaa tggcgtaaat
    26881 acaattgccc gatgcgtaag cttataggga ctacgcatcg gtgcaattta ttgaatttta
    26941 gttgttttta ggccggataa ggcgtttatg aactgacccc caaaacctgg acagtttcag
    27001 ttaaccggct ttttgatact cagtcctgta ttcagggcaa gattacgaaa gcccgctccc
    27061 cgcaaggact gacgccag
//
LOCUS       DACAOP010000057        26759 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.057, whole genome shotgun sequence.
ACCESSION   DACAOP010000057 DACAOP010000000
VERSION     DACAOP010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26759
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.057"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            186..725
                     /locus_tag="IT892_002730"
     CDS             186..725
                     /locus_tag="IT892_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414946.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HAP3135933.1"
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLN
                     QETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDADGTTLTLR
                     IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
                     ISVDQLGFVRIHDIQPVMQ"
     gene            1024..1908
                     /locus_tag="IT892_002731"
     CDS             1024..1908
                     /locus_tag="IT892_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="HAP3135934.1"
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
                     YHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
                     EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
                     LSMNVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLG
                     DDSGNAINGIKTRTNNSIASSHILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGN
                     FNVRSTGWGGYLVVGYNF"
     gene            complement(2085..2432)
                     /locus_tag="IT892_002732"
     CDS             complement(2085..2432)
                     /locus_tag="IT892_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease family protein"
                     /protein_id="HAP3135935.1"
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
                     PFADLKAMMNKKK"
     gene            complement(2561..3532)
                     /gene="secF"
                     /locus_tag="IT892_002733"
     CDS             complement(2561..3532)
                     /gene="secF"
                     /locus_tag="IT892_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HAP3135936.1"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
                     GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     gene            complement(3543..5390)
                     /gene="secD"
                     /locus_tag="IT892_002734"
     CDS             complement(3543..5390)
                     /gene="secD"
                     /locus_tag="IT892_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HAP3135937.1"
                     /translation="MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVA
                     ASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVA
                     LNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     EQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
     gene            complement(5418..5750)
                     /gene="yajC"
                     /locus_tag="IT892_002735"
     CDS             complement(5418..5750)
                     /gene="yajC"
                     /locus_tag="IT892_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAP3135938.1"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     gene            complement(5773..6900)
                     /gene="tgt"
                     /locus_tag="IT892_002736"
     CDS             complement(5773..6900)
                     /gene="tgt"
                     /locus_tag="IT892_002736"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAP3135939.1"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD"
     gene            complement(6956..8026)
                     /gene="queA"
                     /locus_tag="IT892_002737"
     CDS             complement(6956..8026)
                     /gene="queA"
                     /locus_tag="IT892_002737"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAP3135940.1"
                     /translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
                     FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
                     FSYGDAMFITYNPQAINERVGE"
     gene            8119..8700
                     /gene="acpH"
                     /locus_tag="IT892_002738"
     CDS             8119..8700
                     /gene="acpH"
                     /locus_tag="IT892_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP phosphodiesterase"
                     /protein_id="HAP3135941.1"
                     /translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
                     HRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFV
                     CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
                     DSWYDLDAHYDALETRFWQFYPRMMAQASRKAL"
     gene            complement(8705..10522)
                     /gene="malZ"
                     /locus_tag="IT892_002739"
     CDS             complement(8705..10522)
                     /gene="malZ"
                     /locus_tag="IT892_002739"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="HAP3135942.1"
                     /translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
                     EEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
                     PARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
                     DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYR
                     HVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
                     PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGW
                     RLDVVHMLGEAGGARNNMQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAM
                     NYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDT
                     ARFKTLLGRDIARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
                     TALFALYQRMIALRKKSQALRHGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEV
                     VLPASPFLNAVQWQCKEGHGQLTDGILALPAISATVWMN"
     gene            complement(10678..12051)
                     /gene="proY"
                     /locus_tag="IT892_002740"
     CDS             complement(10678..12051)
                     /gene="proY"
                     /locus_tag="IT892_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="HAP3135943.1"
                     /translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
                     IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
                     VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
                     RQLAENQ"
     gene            complement(12127..13446)
                     /gene="brnQ"
                     /locus_tag="IT892_002741"
     CDS             complement(12127..13446)
                     /gene="brnQ"
                     /locus_tag="IT892_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter carrier
                     protein BrnQ"
                     /protein_id="HAP3135944.1"
                     /translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIVWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
                     GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
                     QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAF
                     SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
     gene            complement(13853..15148)
                     /gene="phoR"
                     /locus_tag="IT892_002742"
     CDS             complement(13853..15148)
                     /gene="phoR"
                     /locus_tag="IT892_002742"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HAP3135945.1"
                     /translation="MLERLSWKRLVLELLLCCLPAFILGAFFGYLPWFLLASVTGLLI
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
                     FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMNEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNE
                     KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTP
                     EGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIAKNSD"
     gene            complement(15206..15895)
                     /gene="phoB"
                     /locus_tag="IT892_002743"
     CDS             complement(15206..15895)
                     /gene="phoB"
                     /locus_tag="IT892_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate response regulator transcription
                     factor PhoB"
                     /protein_id="HAP3135946.1"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
                     PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
                     RGTGYRFSTRF"
     gene            16085..17287
                     /gene="sbcD"
                     /locus_tag="IT892_002744"
     CDS             16085..17287
                     /gene="sbcD"
                     /locus_tag="IT892_002744"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HAP3135947.1"
                     /translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAII
                     VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
                     TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
                     YQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
                     ALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVT
                     QPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVE
                     VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLH
                     TLAGEHEA"
     gene            17284..20430
                     /gene="sbcC"
                     /locus_tag="IT892_002745"
     CDS             17284..20430
                     /gene="sbcC"
                     /locus_tag="IT892_002745"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcC"
                     /protein_id="HAP3135948.1"
                     /translation="MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKT
                     TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRAR
                     NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
                     FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVTLLTPEQV
                     QSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKA
                     QPQLAALSLAQPARNLRPHWERIAEHSAALAHIRQQIEEVNTRLQSTMALRASIRHHA
                     AKQSAELQQQQQSLNTWLQEHDRFRQWNNEPAGWRAQFSQQTSDREHLRQWQQQLTHA
                     EQKLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQ
                     NVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPL
                     CGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGATLRGQLDAITKQLQRDENE
                     AQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQDEHERQLRLLSQRHELQGQ
                     IAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLPQEDEEESWLATRQQEAQSWQQRQN
                     ELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALHSQQQTLQQQD
                     VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
                     LVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQD
                     ADNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQ
                     LTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVS
                     HKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKV
                     KKINGLGYSKLESTFAVK"
     gene            20556..21740
                     /gene="araJ"
                     /locus_tag="IT892_002746"
     CDS             20556..21740
                     /gene="araJ"
                     /locus_tag="IT892_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414930.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
                     /protein_id="HAP3135949.1"
                     /translation="MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMI
                     SYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSG
                     FPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTF
                     LLIAVFNIAVMASVYFWVPDIRDEAKGNLREQFHFLRSPAPWLIFAATMFGNAGVFAW
                     FSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIV
                     LALLMLFFCGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFN
                     LGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADTPVLAKP
                     LG"
     gene            complement(21985..22893)
                     /gene="mak"
                     /locus_tag="IT892_002747"
     CDS             complement(21985..22893)
                     /gene="mak"
                     /locus_tag="IT892_002747"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414928.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="HAP3135950.1"
                     /translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
                     TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
                     PWMDEDELRYREEVPCYCGKQGCIETFISGTGFAMDYRRLSGHALKGSEIIRLVEESD
                     PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVGQLIKQFVFGGE
                     CETPVRKAKHGDSSGVRGAAWLWPQE"
     gene            23018..23929
                     /gene="rdgC"
                     /locus_tag="IT892_002748"
     CDS             23018..23929
                     /gene="rdgC"
                     /locus_tag="IT892_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HAP3135951.1"
                     /translation="MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMG
                     WVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEE
                     ITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQNLIEGLGGEAQR"
     gene            complement(24007..24090)
                     /locus_tag="IT892_002749"
     CDS             complement(24007..24090)
                     /locus_tag="IT892_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135952.1"
                     /translation="MTQRPWSKLQRKTHNIAALKIIARRSE"
     gene            complement(24087..24428)
                     /locus_tag="IT892_002750"
                     /pseudo
     CDS             complement(24087..24428)
                     /locus_tag="IT892_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308469.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing protein"
     gene            complement(24576..24860)
                     /gene="ppnP"
                     /locus_tag="IT892_002751"
     CDS             complement(24576..24860)
                     /gene="ppnP"
                     /locus_tag="IT892_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HAP3135953.1"
                     /translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
                     MTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
     gene            complement(24932..25609)
                     /locus_tag="IT892_002752"
     CDS             complement(24932..25609)
                     /locus_tag="IT892_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="HAP3135954.1"
                     /translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREE
                     VMAEYAPEAGEDTILTLLNDNQLAHVSRRKVERDLQGVVEVLDNQGYDVILLMSTANI
                     SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEEMLPVQAQKWQILQKSPVFSL
                     GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFHQRHRDLLQKQLDVPVLLSNVLIAR
                     LAAELLV"
     gene            complement(25867..26058)
                     /gene="yaiA"
                     /locus_tag="IT892_002753"
     CDS             complement(25867..26058)
                     /gene="yaiA"
                     /locus_tag="IT892_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YaiA"
                     /protein_id="HAP3135955.1"
                     /translation="MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEH
                     PTAQEAMDAKKRYEDPDKE"
     gene            complement(26108..26632)
                     /gene="aroL"
                     /locus_tag="IT892_002754"
     CDS             complement(26108..26632)
                     /gene="aroL"
                     /locus_tag="IT892_002754"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroL"
                     /protein_id="HAP3135956.1"
                     /translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMT
                     VAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
                     PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
                     ISEIRSALAQTINC"
BASE COUNT         6770 a         7166 c         6637 g         6186 t
ORIGIN      
        1 ttagtgtcca cggcgaaaca gaatgggcaa tgcatacggc gtcctgacca ggtggttaac
       61 ggaaatctat tttaccctga actgacgata caacaaaggc gcaacgcttt tgagataaag
      121 gatcgatgct ttcgctgctt ttaccctcta ccattaggct aattgcgacg agaaagggac
      181 gacctatgaa tactaacgtt tttcgactgc tcctgctggg aagcctgttc agccttagcg
      241 cctgtgtgca gcaaagtgaa gtgcgacaga tgaaacacag cgtcagcacg ctgaaccagg
      301 agatgacgca actcaatcaa gaaacagtca aaatcactca gcaaaacagg ctgaatgcaa
      361 aatccagcag tggggtttac cttctgcctg gagcgaaaac accggcaaga ctggaaagcc
      421 agatcggtac tttacgtatg tcgctggtga atattacgcc tgatgcagat ggcaccaccc
      481 ttacactacg tattcagggt gagtcgaatg atcccttgcc cgcattcagc ggaactgttg
      541 aatatgggca aattcaggga acaatagaca actttcagga aatcaatgtg cagaatcaat
      601 tgattaatgc ccctgccagc gtcctcgccc ccagcgatgt tgatattccg ttacagttaa
      661 aggggatttc tgtggatcag ttaggctttg tacgtatcca cgacattcaa cctgttatgc
      721 agtaaacgta tttcgggacg attttgtgcg tcccgcaaca tctttccccg tcattttgtt
      781 actctgctta catcacctgg attgatagta aaagtttgca acaagggcga aagtcagtac
      841 aatccccgcc cgaatgtgtg taaacgtgaa cgcaatcgat tacgtaaatg atagaactgt
      901 gaaacgaaac atatttttgt gagcaatgat ttttataata ggctcctctg tatacgaaat
      961 atttagaaac gcaatttgcg cctttttcac tcccgcaagg gattttcaaa cagtggcata
     1021 catatgaaaa aaacattact ggcagccggt gcggtactgg cgctctcttc gtcttttact
     1081 gtcaacgcag ctgaaaacga caaaccgcag tatctttccg actggtggca ccagagcgtt
     1141 aacgttgtcg gaagctatca cacccgtttc ggaccgcaga tccgcaacga tacctacctt
     1201 gagtacgaag cattcgctaa aaaagactgg ttcgacttct atggttatgc ggatgcgccg
     1261 gtattcttcg gcggtaactc cgatgctaaa ggtatctgga accacggttc tccgctgttt
     1321 atggaaatcg aaccacgttt ctccatcgac aagctgacca atactgacct tagcttcggt
     1381 ccgttcaaag agtggtactt cgcgaacaac tacatttacg acatgggtcg taataaagat
     1441 ggtcgccaga gcacctggta catgggtctg ggtaccgata tcgacactgg cctgccgatg
     1501 agcctgtcca tgaacgtcta tgcgaaatac cagtggcaga actatggcgc agcgaacgaa
     1561 aacgagtggg acggttaccg tttcaaaatt aaatactttg tgccgattac cgatctgtgg
     1621 ggcggtcagc tgagctacat cggcttcacc aacttcgact ggggttccga tttaggggat
     1681 gacagcggta acgcaatcaa cggtattaag acccgtacta ataactctat cgcttccagc
     1741 catattctgg ctctgaacta cgatcactgg cactactctg tcgtagctcg ttactggcac
     1801 gacggtggtc agtggaacga cgatgcagaa ctgaacttcg gcaacggcaa cttcaacgtt
     1861 cgctctaccg gctggggtgg ttacctggta gtaggttaca acttctgatt atgaaaatgc
     1921 cgggatttat tcccggcatt tctgattgtt aacaacgtgt gctttgttca tgccggatgc
     1981 ggcgtaaacg ctttgtccgg ccaacaaaag cacgtaaatt caatatattg ctgaaataac
     2041 gtaggcctga taagcgtagc gcatcaggca attttacgtt ttaatcactt cttcttgttc
     2101 atcatcgctt tcaggtcagc gaatgggttg tacttcgctt caccgacatc tttctgcgca
     2161 tcttcccctg cgataacggt cgtaccatac tgatccgctt cggtatattt cgaatgctca
     2221 tgatcgtggc aatagagaca caacaattcc cagttactgc catcttccgg gttattggta
     2281 tggtcgtgat caatgtggtg aacggtaagt tcacgcaggt tggaataaac aaactcgcgg
     2341 gaacagcgac cgcagaccca cggatagatt tttaatgctt tttcgcgata gccgctttct
     2401 aaccgcgcat agttttttgg gatgatagcc atgaaaagtt acctggatga aatgtagggt
     2461 tacgcgcagt ttcccaagat gcggggattt tcgcaatctc catacatcaa aaaaaatccc
     2521 gatcttctga ccgggatttt caacatcaac gggaacttga ttacggcaga attgacggct
     2581 gatccgcccc ttctttttcc actttctgct gcaacatgtg ttcgcgcttc atacccagtt
     2641 tcagagccaa cgcagatgcc acatagatgg aagatgcagt accgatggaa acaccgataa
     2701 gcatggtcag cgagaagcct tccagtaccg gaccaccgaa gaggtacagc atcaggataa
     2761 ccatcaaggt agtaccggat gtgatcaagg tacggtgcag cgtctgggtc aaggacacgt
     2821 taaagatttc gtaaggcgta ccgcgacgga tcttgcggaa gttttcacga atacggtccg
     2881 ataccacgat actgtcgtta agcgagtaac cgataaccga catcaacgat gccacaatgg
     2941 tcaggtcaat ctcgatatgg aataacgaca aaatacccag cgtaatgata acgtcgtgcg
     3001 ccagcgcaat aaccacccct gccgccagtc gccactcaaa gcggaaacct acgtacacga
     3061 ggatagacag cagcgctgcc atcaacgcca tcgcaccggt ttgcgcaagg tctgccccca
     3121 cgctcggacc gacgaactca atacgcttca ctgctgcatt ctgattggtg gattcgttaa
     3181 tcaccttcag aacctggctg cccaacacct gaccgccggt ttcgccttca gcaggcggca
     3241 tacggaccat gatgtcatgg ctgctaccaa agttttgcag catcggctct tcaaaaccgg
     3301 ctttttgcaa tgcatcacgc attacgtcaa tttcagccgg tttttcgagc gtaatttcaa
     3361 taaccgtacc accggtgaaa tccagccccc agttaaagcc gcgcacgccc ataataacga
     3421 tagcagcgat taacagcaga ccagagatgc cgaaagccca gtagtcccag cgcataaagt
     3481 catagacttt acggccgtgg tttagttgtt caacagtata ttcctgtgcc acatcgcact
     3541 cctcagattg acagcttctt gacgcgcttg ccgccatata gcaggtttac gatggcacgc
     3601 gtaccgacaa tcgcggtaaa catcgacgtc gccacaccga taccggtagt aatcgcgaac
     3661 cctttaattg ccccggtacc cactgcgtac aggatgatga ctttaatcag cgtggtgatg
     3721 ttcgcatcga agatagaact gaatgcgcca cgataacctt catcaattgc ctgttgaaca
     3781 gtacgtccgt tgctcaactc ttctttaata cgttcgttga tcagtacgtt cgcatcgacc
     3841 gccaccgcaa gggttaagac gatacccgcg atacctggca tactcagcgt tgcgcctggc
     3901 aacagcgaca taatgccgac gattaagatc aagttggcaa tcagagcact ggtcgcaatc
     3961 agaccaaact tcttatagaa gatgatcatg aacagaatag aaaccagcag accggcaagg
     4021 caagcctcca gcccctgttc aatgttctgc atacccaggg ttgggccaat ggtacgttct
     4081 tcaacaatct gaatcggcgc gatcaacgca ccggcacgca gcagcagtga cagctgacgg
     4141 gcttcgttcg ggttgttgat gccggtgata cggaagctgt tacccagacg agactggatg
     4201 ttggcgatgt taatcacctc ttcctgtttc accagaaccg cacgaccatt tgcatctttc
     4261 ttaccgctgt ctttgtactc cacaaacagg gttgccatcg gtttgccgat gttgtcctta
     4321 gtgaagttag acatgatgtt accaccagcg ctatcgagcg agatgttaac ctgcggttgg
     4381 ttgtattcgt cctggctgga agtggagtcg gtgatatggt caccggtcag aattacgcgt
     4441 ttgtacagca caactggctg accttcgcgg gtctgtttca cttcagagtc gcccggtacg
     4501 cgaccggatg ccgcagcggc ctggtcaacg ttggtgttta ccagacggaa ttccagcgtt
     4561 gccgtcgcac ccagaatctc tttcgcacgc gcagtgtcct gaatacctgg cagttcaaca
     4621 acgatacggt cagcaccctg acgctgaacc accggctccg ccacgccaag ttggtttaca
     4681 cggttacgca ggatattaat gttctgctgc accgcatatt cacgcgcttc actcagacga
     4741 gcatcgctca ttaccgcacg cagctggttg ctgccctggc tgctaatcac caggtccgga
     4801 tggcgcttgc tcagatacgc aatggcttca tcacgagctt tagcatcgcg gaaagtgatg
     4861 ctcaggccgt agttgttttc tttacgaaca gtggtatacg ggatgccctt ttcgcgcagg
     4921 tcactgcgta ggctatcgat attttgttcc tggagtttgc caagcgcggt gtccatatcc
     4981 acttccatca ggaagtgaac gccgccacgc aggtcaaggc cgagcttcat cggctcagcg
     5041 tgaatagctg ccagccagcg cggcgttgcc ggggcaaggt taagcgccac gacgtatttg
     5101 tcacccataa cgcccattaa tgcttcacga gcgcgcaact gggtgtcagt ggagtcgaag
     5161 cgcgcaagaa tagcgccctc ttccagtgcc acagacttag cagttatttt ttcttcttgt
     5221 aacgttttct ggacctggat cagcgtttgc tcactggcgg cgactccgcg cgcaccagtg
     5281 atctgaacag ccggatcctc accaaacagg ttgggaagcg catacagcag accgatgaca
     5341 atcaccacga tcagcatgac gtacttccac aaaggataac ggtttaacac ggcaattccc
     5401 ttagggaaaa attttaatta cagcgccttc atggtgcctt tcggcaggac ggcagctacg
     5461 aagtcacgtt taataactac ttcagtggtg tcattcagcg cgatagcaat gtagccgttt
     5521 tccgctactt tggttacgcg accaaccagg ccaccgttcg tcagaacttc atcacctttg
     5581 gcaatggagt ccatcagctt tttgtgttct ttggtgcgct tctgctgtgg acgcaggatc
     5641 atgaaataga aaatcagacc gaataccacc agcatcaaaa tcaaagacat cgggctacct
     5701 tgcgccggtg cacccgttgc cgctaccgca tcagaaataa aaaagctcat taaatttccc
     5761 tcattattaa tattaatcaa cgttcaaagg tggtacttct cgcccctgac gctggtaaaa
     5821 atcagttacg aagctctcta atttaccctc ttcaatagcc ttgcgtaaac ccgccatcaa
     5881 acgctggtag taacgaaggt tatgaatggt gttgagtcgc gcgcctaata tttcgttgca
     5941 acggtcaaga tgatgcaagt aagcgcgtga ataattgcga caggtgtagc aatcacactc
     6001 aggatcgagt gggccagtat cgctcttata cttcgcattg cggattttca ccacgccatc
     6061 ggtcacgaac aaatgaccat ttcgggcgtt gcgggttggc attacgcagt caaacatatc
     6121 gataccacga cgtacgcctt caaccaggtc ttctggttta ccaacgccca tcaggtaacg
     6181 cggtttgtct gccggaattt gcgggcatac atgctccaga atgcggtgca tatctgcttt
     6241 cggctcaccc acagccagac cgccgacagc gtagccatca aaaccgatat ctaccagacc
     6301 tttaacagaa atatcacgta aatcttcgta aacgctgccc tggatgatac caaacagcgc
     6361 atttttgttt ccgagactgt caaaacgctc acggctacgc ttcgcccaac gcagagacat
     6421 ctccatggag cgttttgcgt aatcccagtc agcaggatac ggcgtacact catcaaagat
     6481 catgacgata tccgaaccaa gatcgtactg aatctccatt gatttttcag gatcgaggaa
     6541 aatcggatcg ccgttgatcg ggttacggaa gtgcacgccc tgttcggtga ttttacgaat
     6601 atcgccaagg ctgaagacct ggaagccgcc ggagtcggtg aggatcggcc ccttccactg
     6661 cataaaatcg tgcagatcgc cgtgcagttt catgatttcc tggcccgggc gcagccacag
     6721 gtggaaggtg ttgccgagga taatttgcgc gccagtggct tcaacttctt ccggcgtcat
     6781 cccttttacg gtgccgtagg tgccaacagg cataaaacaa ggcgtttcca ctacgccacg
     6841 atcaaagacc aggcggccac ggcgtgcgcg accgtcggtg gtgtccagtt caaatttcat
     6901 tttttctcca ctacgtcaga aaaacagtcc aacgttttaa accagcgccg cggaattact
     6961 ccccgacgcg ctcattaatt gcctgcggat tgtacgtgat aaacatcgca tcaccgtaac
     7021 taaaaaagcg atatttctct tctaccgctg ctttataggc gttcatggtg tgttgataac
     7081 cggcaaaggc cgaaaccagc ataatcagcg tcgactctgg caagtggaag ttcgtcacca
     7141 gcgcatcgac cactttgtac tggaagcccg gatagataaa gatttgggta tcgtcgaaga
     7201 acggttcaat gagatcgttt ttcgctgcct gagccgcgct ttccagcgaa cgtactgaag
     7261 tggtgccaac cgcaatcacc cggttaccgc gcgctttcgc cgccagtacc gcgtctacca
     7321 catcctgcgg tacttcagcg tattccgagt gcatgatgtg atcttcaatg gtgtcgacgc
     7381 gcaccggctg gaaggtgccc gcaccaacgt gcaacgtcac aaacgccatc tccacgcctt
     7441 tggcgcgcaa tttttccagc aaaggctcgt caaaatgcag acctgcggtc ggggctgcaa
     7501 ccgcgcccgg tttttcgcta taaacggttt gataaagttc gcggtcagcg tcttcgtccg
     7561 gacggtcgat atacggcggc agcggcatat ggccgatgct gttgagaata tccagcaccg
     7621 agcgttcatc attaaattcg acttcaaaca gtgcgccgtg gcgcgcggtc attgttgcgt
     7681 taatactttc gtcatcgccc agcagcagtt ctgcgccagg ttttggcgct ttcgaggcgc
     7741 gaatatgcgc aagaatgcgt ttgtcgtcga gcatccgttc aaccagcact tcaatcttgc
     7801 cgccgctggc tttacgccca aacaggcgcg ccgggatcac gcgggtatta ttaaaaacca
     7861 gaagatcgcc ggggttgagc ttatcaagta aatcggtgaa agtaccgtgc gtcagcgcgc
     7921 ccgtcggccc gtccagcgac agtaaacgac agctactgcg ttcaggcatg ggatagtggg
     7981 caatcaggga ttcgggcaat tcaaaggaga aatcggtaac gcgcatgaca ctgactcaga
     8041 ctaaaataag aggcgggtag tctagtgccg gggcgctctc cctgcaacct ttaccccctt
     8101 ttggatagaa tataatcgat gaatttttta gctcacctgc atttagccca tctcgcggaa
     8161 agctcgcttt ccggcaattt actggctgat ttcgtacgcg gaaatcctga agaaagtttt
     8221 ccgcccgacg tcgtggctgg cattcatatg catcgacgta tcgacgtatt gactgacaat
     8281 ctgccggaag tccgcgaagc acgggagtgg tttcgtagtg aaacgcgccg cgttgcgcct
     8341 attacgctgg atgtcatgtg ggatcacttt ctttcccgcc actggtcgca gctgtcgccg
     8401 gactttccgc tacaggaatt tgtctgttat gcccgcgagc aagtgatgac gattttgccg
     8461 gactcaccgc cacgttttat caatctgaac aattacttgt ggtcagagca gtggctggtg
     8521 cgctatcgcg atatggattt catccagaac gtgttaaacg gcatggcaag ccgccgccca
     8581 cgtctggatg ccctgcgtga ctcctggtac gatttagacg ctcattatga cgccctcgaa
     8641 acccgcttct ggcagtttta tccgcggatg atggcgcagg cgtcacgcaa ggcgttataa
     8701 aacgttagtt catccatacc gtagccgaaa tggcaggcaa agccagaatc ccgtcagtca
     8761 gttgcccatg cccttctttg cattgccatt gcacggcatt gagaaacggt gacgcgggta
     8821 gcaccacttc acaggcctcg ccacggttga ttgccaccag tacacgttgc tgattcagca
     8881 cgcggacaaa taccaccacg ttatcttccg catacagcac ctgacagccg ccatgacgta
     8941 gcgcctgact tttcttacgc agcgcaatca ttcgctggta cagcgcgaat aacgccgtat
     9001 cctgcttttc cacctgccag gggaacggtt tacggcaaaa cggatcgttt ttgccatcca
     9061 gtcctacttc atcaccgtaa taaatgcacg gtacaccagg ccaggtgaac agccagacca
     9121 ccgccagcgg caggcgcgca atatcccgac cgagcagcgt tttaaatcgc gcagtatcgt
     9181 ggctgtcgag ctgattaaac atacgtaatt gttgttgatg agaaagccct gcgcggtaat
     9241 tatccatcca ggccatacag gtttgggcat caatttgctg cggatcgtaa gagatatcgg
     9301 tattggcaag aaatccccac aacgggaatg tgaagccacg atagttcatg gcggcatctt
     9361 ccacatcggc ctgtaaccat tgccgtgcat cgccaaaatg ttcgccgaca atatacgctt
     9421 ccggctgggt ttctttcgcc gcttcggtga tcccggcaac gtgctgcata ttattgcgcg
     9481 ccccacccgc ctcccccagc atatgcacca catccagccg ccagccgtcc atattccacg
     9541 gcgctttcag ccagtggcgg acaatactgt cttccccgcg ataaatttca ttcaccagac
     9601 tttccgactg ataatccagc ttcggcaagc tggcatagcc aagccagtcg agcgccgtgc
     9661 catcatcact aaacgagtac cagtcgcgcc agggcgattc ggggttgtga caagcaccac
     9721 ccgtgccacg attatgcctg tcaaaccagg catgggaatc gccactgtgg ttaaacacgc
     9781 cgtccagcac cagccgcatt cccagctgct gcgtattgtg tcgcaaacgc agcaacgccc
     9841 catcaccgcc aaactgcgga tcgacatggc gataatcctc ggtatcgtat ttatgtacgc
     9901 tgggagcttt aaacaccgga ttgagataca gcgctgtcac gccaagcttt ttcagatacg
     9961 gcagtttttc gcttatcccg tccagatcgc cgccatagaa cgttgatccg cccgcctgcg
    10021 ccgtgaccgg ttcatcccag tcacgcaaga tgatctcttg tccggctgca tgatggtaat
    10081 agacatgatc ctgttcagct tcacgaggaa gactacgcgc aaaacgatca gggaagatct
    10141 gataaaaaat ctgatccgca gcccattgtg ggccgatatc cggtacatcg acggcaaact
    10201 gctccagtcg tgccggcggc attcggctga agccctgcgg tgtaaaccaa cgctggcgat
    10261 cgtgccacag cagtttgaaa ctgtaacgcc gccggggttg tccgctggag agatcaatcg
    10321 ccgcacgcca tgcggtgacg ccaggctgcg gctgactgcg ctgcttatgc atcggtactg
    10381 acatttcttc gttatcgtgt tctgtacgca gcataatgcg ctgcggtggg tcttcgcccg
    10441 tcagccacag tgtaatgagc agttgatctt tgctttgttt aacaaatggg ggcaccggca
    10501 ggtgccatgc atttaacatc ataattcccc tgtgatgaaa atctgatcac cttgccatag
    10561 cctaatgcag gatcactcat catctgaagg atatttgggg gaggaggacg ggggcggata
    10621 actttcggaa tagccggatc aggatttcct cctgaaccgg cttacagaac gcaaggatta
    10681 ctggttttca gccagctgac gatcgtggcg gcgtttaaac atccagccaa tcaacagcac
    10741 aacaatccac gcgaaaccga catacagcga gatacgcgta tccgggtgat aaccaatcaa
    10801 cccgataata aagagcagga aaatcagccc gccgatggtc gttgctaccc cacccggcac
    10861 tttaaatttc agcgccttaa cttcttctgg cggcaaacgg cgacggaagg caatttgcga
    10921 cagcaggatc ataatccaca cccacaccgt ggcgaaggtt gccagcgaag cgatcaccag
    10981 gaagacgttt tccggcatga tgtagttcag atacaccgca aacagcagcg cggtagtcat
    11041 caccagcacc gtaacccacg gaataccgcg acgcgacgtt ttgctgaaaa ttttcggcgc
    11101 gctgccctgc tctgccatac cgtggagcat acggcctacg ccaaatacat cactgttaat
    11161 tgccgacagc gaagcagtca gcacaacaaa gttaagaatg ctggcggcaa aggtaatgcc
    11221 catatgctgg aacgtcagca cgaacgggct accggcagtg ccaacctgat tccacgggta
    11281 gatagacata atgacgaaca gcgtaccgac gtagaacacc agaatacgca tcggcacgga
    11341 gttaatcgca cgcggtatcg atttctcagg atctttcgct tcaccggcgg taatcccgat
    11401 aatttcgatc ccaccgtaag caaacatcac catttgcaac gacattacca tgccaagcca
    11461 gccgttactg aagaagccgc cgttgctcca caggttatga ataccggtcg gttgcccgcc
    11521 gttgccaatc ccccagatga tgatgccgaa accggcgaca atcatgatga tgatggtggc
    11581 gactttaaag aacgagaacc agaattccag ctcaccgaat accttcacgc tcatcaggtt
    11641 tacggcgcaa atgatcagca ccacgctcag tacccaaatc cagtgcggca ccgtcgggaa
    11701 ccagacaccc atatagatac caaaagcggt cacatcggcg atggcgacaa taaggatttc
    11761 aaagcagtag gtccagccgg taatgtaacc tgccagcggg ccgaggtttt cctgcgcata
    11821 acgcgagaaa gagctggcgg ccgggttatg taccgacatt tcccccagcg cacgcataat
    11881 gatatacgcc gcgataccac cgataatata ggccaacaac acgctcggac cggccatttt
    11941 gatggcgtct gccgaaccgt aaaacagccc ggtgccaatt gctgaaccca gtgccataaa
    12001 gcgtatgtgg cgggtactta gcccacgctt tagcttgttc ttactttcca tcaattccta
    12061 acccatcaac acaataaaaa accacggggc atcgcagccc cgtggttaaa acaaatgttc
    12121 agtgatttag tgagcgctgg aggtcacctg acgacctgcc gcgcgatccc agataatggc
    12181 cagaaccacc atcaccactg ttggcattaa ccacgccaga ccttgttcgg ccagcggtaa
    12241 acgctgcgcc caggacggta agatatcgct gaatgcagat gctttgatcc cgtcgagaat
    12301 accaaaaagc aggctgataa acatcggcgg agcaatcacg cgggacgaat tatgccacca
    12361 tgagcgtgta aaacttaata caaccagtgc gatacacggc ggataaatag cggtcagcac
    12421 cggtacggag atctggatca gctggcttaa gccgaggtta gaaaccacca tcgagaagcc
    12481 gccgaggata aacaccagcg tacgataaga gagcggtacg tactgggcaa agaattctgc
    12541 acaagcacag gtcaggccaa ctgccgttac caggcaggcg atgaagatta acgccgccag
    12601 caggaagcta ccgccgccgc caaaggtgtg ctgaacgtaa gcatgcagaa tagcagcgcc
    12661 gtttgcagac tgatcgacca gcgacgcgct gtctgacccc agacggaaca gcgccaggta
    12721 cagcagagtc agaccaacac ccgccatcag gccagcccag acggtataac gggtcagcag
    12781 acgcgcttcg gtaacgccac gagaacgcgc cgcgttaaca ataacgatac caaacaccat
    12841 tgcgcccagc gtatccatgg tcagatagcc gttaacgaag ccgttagaaa acgcagcgtt
    12901 ttgataagcc tcagtcgccg tgctgataga acccgccggc cagacaatag cggcaacaga
    12961 caggatgacc agcgcgataa ttttcagcgg cgcaaggaag ttgcccacgg tatccagcag
    13021 cttgcccgga tagagcgaaa ccagaataac gatagcgaaa tagaccaggc tgtagataaa
    13081 cagcggcagc gcggaatcac ccgtcagcgg cgcaatcccc acttcaaagg aaacggtagc
    13141 tgtacgcggc gtagcgaaaa gcggccccac cgccaggtaa caaaccgttg ccagcagtac
    13201 gccagcgact ttaccgattg gcgtgctgag gctgtcaaca ccgccgccaa cttttgccag
    13261 cgccactacc gttaataccg gcaggccaac ggcagtaatg aggaagccga atgccgcagt
    13321 ccagacgtgt tcgcctgcct gtaagccgac cattggaggg aaaataatgt tacctgcgcc
    13381 gacgaacaac gcaaatgtca taaagcccag agcgatgata tcgcgcgatc ttaattgatg
    13441 ggtcataaat catactgcct gtggatgtgg tgttgtaacg ttaaattttt gtgccaatcc
    13501 ctggggatga tacagcggta tatttaaaca attttagcgg gaaatactcc caaccaggcg
    13561 cggcgaagaa tagtttttcg atttaccgcg ttaatgcagt cagtatgaca gcacctgaag
    13621 cgcaatttaa acgcttataa cgttttaaag caaggaggga tctaaaaacc agaggtatat
    13681 agcgataaga aatcaccaac cagtataaaa cactatttcc gtgaaaaaga catggctaat
    13741 catgcgaaca aaaaatcacc aaccgttgta aaatctaacg cccgtatttt gactgcaaag
    13801 aaaataagcc agcatcgact ggcttatggc aataaaagat gacaaaggcg gattaatcgc
    13861 tgtttttggc aattaaacgt tccgggataa caaaactgaa acgtgttcct tttcctactg
    13921 tactctcaat attcaggcga ctttcgtgat gattcacagc atgtttcacg atcgctaacc
    13981 ctaatccgct accgccggtt tgccgggaac gcgctttatc aacgcgataa aaacgctcgg
    14041 tcaggcgcgg aatatgctcc ggtgcaatgc ccggtccgtt atcttcaacg ctaaattcgg
    14101 caccgtgcgg cactcgctgc cagcgtacgg tgatatgcgt gccttccggc gtatgattca
    14161 cggcgttata gaccaggttc gaaatcgcac tgcgtagctg atcttcgttg ccagacacct
    14221 tgaggccgtt atctatctca aaggtaaatg tctgtttttt ctgactcaga gtctgagcct
    14281 cgcgctcaac aacgcgcagc atcatcggca catcaacctt ttcattgagc aaatgcgtcg
    14341 gtgcggcttc tattttcgac agcgtcagca attgcttcac cagtccttcc atccgctggg
    14401 tctgctcgcg catggtgtgc aacgcttttt cgcgtaccgc gccttccagc ggctgctcat
    14461 tcatcatctc caggtaaccc tgtaacacgg tcaatggcgt acgtaactca tggctcacgt
    14521 tggcaaaaaa gttacgccgc gccccttcca gttgatgcat ttgcgtgaca tcacgcgcca
    14581 ccatcagcaa ctgtttgtgg gtataaggca tgacgcgaat ttccagatgc cgcccggtgt
    14641 tgagcaccag attgagcggg cgagaaaaat cacgcgtttt cagatattgc gtaaactccg
    14701 ggtaacgcag taggttaagg atgttctgcc cattatcttc cggccagcgc aaaccaagaa
    14761 tttgttgcgc cagaccgtta caccagaaaa taccgccctc ttccgtggtc agcaccaccg
    14821 cgtcgggcag cgactccgcg ccgctacgaa agcgtttaat cagattgccc agttcacggc
    14881 ggcgtttttt atttcgcagc tgcatctggt gtaagccgta tagtagcggt tcccagctac
    14941 cacgccccgg tggcggggtc atactgcgat ccacccacag ccaccatgaa aggcgcaata
    15001 aattccagaa atgccagata agcagtcctg ttaccgatgc cagcaaaaac cagggcaggt
    15061 aaccaaaaaa tgcacccagg atgaaagccg ggaggcagca aagtagcagc tccagcacca
    15121 gccttttcca cgacagccgt tccagcacgt aagatactcc agttaagaaa tcataagccc
    15181 tgctctgcgt ccgatgagca aggcgttaaa agcgggttga aaaacgatat cctgtaccgc
    15241 gcacggtctg caccatgcgg tcatgcccgc cgggctccag tgctttacgc aggcgacgaa
    15301 tgtggacatc gaccgtgcgg tcttccacat acacgttagt tccccagacg tggtttaaca
    15361 gctgctcgcg gctgtacacg cgctcaggat gcgtcataaa aaagtgcagc agtttaaatt
    15421 ctgtcggccc catctccagc ggctcttcgc ccgccatcac tcggtgagat gtcgggtcga
    15481 gacttaatcc ctgcatctca atcacctctt ccaccgccat tggcgaaata cggcgcatta
    15541 ccgctttgat tcgcgccacc agctccttcg gcgaaaacgg cttggtgata tagtcatccg
    15601 cgccggtttc aaggccgcgc acgcgatctt cttcttcccc tctggcggtc aacatcacca
    15661 ctggaatatc ccgggtcatc gactcgcgct tgaggtgttt gatgaactgg ataccggagc
    15721 cgccaggtaa catccagtcg aggagaatta aatccggcca gggttcattc agttgattca
    15781 cagcactgtc ataatcttcc gcttcgaccg gctgaaagcc attttgttcg agcacgaagc
    15841 agaccatttc gcgaattgga gcttcatctt ctacgaccag aatacgtctc gccatgattt
    15901 gccctgttgt aataaatagg ttgcgatcat taatgcgacg tcattatgcg tcagatttat
    15961 gacagattta tgaaaagctc gtcgcacata tcttcaggtt attgatttcc gtggcgcaga
    16021 aaaaagcaaa tggcacatct gtttgggtat aatcgcgccc atgctttttc gccagggaac
    16081 cgttatgcgc atccttcaca cctcagactg gcatctcggc cagaacttct acagtaaaag
    16141 ccgcgaagct gaacatcagg cttttcttga ctggctgctg gagacagcac aaacccatca
    16201 ggtggatgcg attattgttg ccggtgatgt tttcgatacc ggctcgccgc ccagttacgc
    16261 ccgcacgtta tacaaccgtt ttgttgtcaa tttacagcaa actggctgtc atctggtggt
    16321 actggcagga aaccatgact cggtcgccac gctgaatgaa tcgcgcgata tcatggcgtt
    16381 cctcaatact accgtggtcg ccagcgccgg acatgcgccg caaatcttgc ctcgtcgcga
    16441 cgggacgcca ggcgcagtgc tgtgccccat tccgttttta cgtccgcgtg acattattac
    16501 cagccaggcg gggcttaacg gtattgaaaa acagcagcat ttactggcag cgattaccga
    16561 ttattaccaa caacactatg ccgatgcctg caaactgcgc ggcgatcagc ctctgcccat
    16621 catcgccacg ggacatttaa cgaccgtggg ggccagtaaa agtgacgccg tgcgtgacat
    16681 ttatattggc acgctggacg cgtttccggc acaaaacttt ccaccagccg actacatcgc
    16741 gctcgggcat attcaccgcg cacagattat tggcggcatg gaacatgttc gctattgcgg
    16801 ctcccccatt ccactgagtt ttgatgaatg cggtaagagt aaatatgtcc atctggtgac
    16861 attttcaaac ggcaaattag agagcgtgga aaacctgaac gtaccggtaa cgcaacccat
    16921 ggcagtgctg aaaggcgatc tggcgtcgat taccgcacag ctggaacagt ggcgcgatgt
    16981 atcgcaggag ccacctgtct ggctggatat cgaaatcact actgatgagt atctgcatga
    17041 tattcagcgc aaaatccagg cattaaccga atcattgcct gtcgaagtat tgctggtacg
    17101 tcggagtcgt gaacagcgcg agcgtgtgtt agccagccaa cagcgtgaaa ccctcagcga
    17161 actcagcgtc gaagaggtgt tcaatcgccg tctggcactg gaagaactgg atgaatcgca
    17221 gcagcaacgt ctgcagcatc ttttcaccac gacgttgcat accctcgccg gagaacacga
    17281 agcatgaaaa ttctcagcct gcgcctgaaa aacctgaact cattaaaagg cgaatggaag
    17341 attgatttca cccgcgagcc gttcgccagc aacgggctgt ttgctattac cggcccaaca
    17401 ggtgcgggga aaaccaccct gctggacgcc atttgtctgg cgctgtatca cgaaactccg
    17461 cgtctctcta acgtttcaca atcgcaaaat gatctcatga cccgcgatac cgccgaatgt
    17521 ctggcggagg tggagtttga agtgaaaggt gaagcgtacc gtgcattctg gagccagaat
    17581 cgggcgcgta accaacccga cggtaatttg caggtgccac gcgtagagct ggcgcgctgc
    17641 gccgacggca aaattctcgc cgacaaagtg aaagataagc tggaactgac agcgacgtta
    17701 accgggctgg attacgggcg cttcacccgt tcgatgctgc tttcgcaggg gcaatttgct
    17761 gccttcctga atgccaaacc caaagaacgc gcggaattgc tcgaggagtt aaccggcact
    17821 gaaatctacg ggcaaatctc ggcgatggtt tttgagcagc acaaatcggc ccgcacagag
    17881 ctggagaagc tgcaagcgca ggccagcggc gtcacgttgc tcacgccgga acaagtgcaa
    17941 tcgctgacag cgagtttgca ggtacttact gacgaagaaa aacagttaat taccgcgcag
    18001 cagcaagaac aacaatcgct aaactggtta acgcgtcagg acgaattgca gcaagaagcc
    18061 agccgccgtc agcaggcctt gcaacaggcg ttagccgaag aagaaaaagc gcaacctcaa
    18121 ctggcggcgc ttagtctggc acaaccggca cgaaatcttc gtccacactg ggaacgcatc
    18181 gcagaacaca gcgcggcgct ggcgcatatt cgccagcaga ttgaagaagt aaatactcgc
    18241 ttacagagca caatggcgct tcgcgcgagc attcgccacc acgcggcgaa gcagtcagca
    18301 gaattacagc agcagcaaca aagcctgaat acctggttac aggaacacga ccgcttccgt
    18361 cagtggaaca acgaaccggc gggttggcgt gcgcagttct cccaacaaac cagcgatcgc
    18421 gagcatctgc ggcaatggca gcaacagtta acccatgctg agcaaaaact taatgcgctt
    18481 gcggcgatca cgttgacgtt aaccgccgat gaagttgcta ccgccctggc gcaacatgct
    18541 gagcaacgcc cactgcgtca gcacctggtc gcgctgcatg gacagattgt tccccaacaa
    18601 aaacgtctgg cgcagttaca ggtcgctatc cagaatgtca cgcaagaaca gacgcaacgt
    18661 aacgccgcac ttaacgaaat gcgccagcgt tataaagaaa agacgcagca acttgccgat
    18721 gtgaaaacca tttgcgagca ggaagcgcgc atcaaaacgc tggaagctca acgtgcacag
    18781 ttacaggcgg gtcagccttg cccactttgt ggttccacca gccacccggc ggtcgaggcg
    18841 tatcaggcgc tggagcctgg cgttaatcag tctcgattac tggcgctgga aaacgaagtt
    18901 aaaaagctcg gtgaagaagg tgcgacgcta cgtgggcaac tggacgccat aacaaagcag
    18961 cttcagcgtg atgaaaacga agcgcaaagc ctccgacaag atgagcaagc acttactcaa
    19021 caatggcaag ccgtcacggc cagcctcaat atcaccttgc agccactgga cgatattcaa
    19081 ccgtggctgg atgcacaaga tgagcacgaa cgccagctgc ggttactcag ccaacggcat
    19141 gaattacaag ggcagattgc cgcgcataat cagcaaatta tccagtatca acagcaaatt
    19201 gaacaacgcc agcaactact tttaacgaca ttgacgggtt atgcactgac attgccacag
    19261 gaagatgaag aagagagctg gttggcgaca cgtcagcaag aagcgcagag ctggcagcaa
    19321 cgccagaacg aattaaccgc gctgcaaaac cgtattcagc agctgacgcc gattctggaa
    19381 acgttgccgc aaagtgatga actcccgcac tgcgaagaaa ctgtggtatt ggaaaactgg
    19441 cggcaggtac atgaacaatg tctcgcatta cacagccagc agcagacgtt acagcaacag
    19501 gatgttctgg cggcgcaaag tctgcaaaaa gcccaggcgc agtttgacac cgcgctacag
    19561 gccagcgtct ttgacgatca gcaggcgttc cttgcggcgc taatggatga acaaacacta
    19621 acgcagctgg aacagctcaa gcagaatctg gaaaaccagc gccgtcaggc gcaaactctg
    19681 gtcactcaga cagcagaaac gctggcacag catcaacaac accgacctga cgacgggttg
    19741 gctctcactg tgacggtgga gcagattcag caagagttag cgcaaactca ccaaaagttg
    19801 cgtgaaaaca ccacgagtca aggcgagatt cgccagcagc tgaagcagga tgcagataac
    19861 cgtcagcaac aacaaacctt aatgcagcaa attgctcaaa tgacgcagca ggttgaggac
    19921 tggggatatc tgaattcgct aataggttcc aaagagggcg ataaattccg caagtttgcc
    19981 caggggctga cgctggataa tttagtccat ctcgctaatc agcaacttac ccggctgcac
    20041 gggcgctatc tgttacagcg caaagccagc gaggcgctgg aagtcgaggt tgttgatacc
    20101 tggcaggcag atgcggtacg cgatacccgt accctttccg gcggcgaaag tttcctcgtt
    20161 agtctggcgc tggcgctggc gctttcggat ctggtcagcc ataaaacacg tattgactcg
    20221 ctgttccttg atgaaggttt tggcacgctg gatagcgaaa cgctggatac cgcccttgat
    20281 gcgctggatg ccctgaacgc cagtggcaaa accatcggtg tgattagcca cgtagaagcg
    20341 atgaaagagc gtattccggt gcagatcaaa gtgaaaaaga tcaacggcct gggctacagc
    20401 aaactggaaa gtacgtttgc agtgaaataa ctattcagca ggataatgaa tacagagggg
    20461 cgaattatct cttggccttg ctggtcgtta tcctgcaagc tatcacttta ttggctacgg
    20521 tgattggtag ccgttctggt ggttgtgatg gtggtatgaa aaaagtcatt ttatctttgg
    20581 ctctgggcac gtttggtttg gggatggccg aatttggcat tatgggcgtg ctcacggagc
    20641 tggcgcataa cgtaggaatt tcgattcctg ccgccgggca tatgatctcg tattatgcac
    20701 tgggggtggt ggtcggtgcg ccaatcatcg cactcttttc cagccgctac tcactcaaac
    20761 atatcttgtt gtttctggtg gcgttgtgcg tcattggcaa cgccatgttc acgctctctt
    20821 cgtcttacct gatgctcgcc attggtcggc tggtatccgg ctttccgcat ggcgcatttt
    20881 ttggcgtcgg agcgatcgtg ttatcaaaaa ttatcaaacc cggaaaagtc accgccgccg
    20941 tggcggggat ggtttccggg atgacagtcg ccaatttgct gggcattccg ctgggaacgt
    21001 atttaagtca ggaatttagc tggcgttaca cctttttatt gatcgctgtt tttaatattg
    21061 cggtgatggc atcggtctat ttttgggtgc cagatattcg cgacgaggcg aaaggaaatc
    21121 tgcgcgaaca atttcacttt ttgcgcagcc cggccccgtg gttaattttc gccgccacga
    21181 tgtttggcaa cgcaggtgtg tttgcctggt tcagctacgt aaagccatac atgatgttta
    21241 tttccggttt ttcggaaacg gcgatgacct ttattatgat gttagttggg ctagggatgg
    21301 tgctgggaaa tatgctaagt ggcaggattt caggacgtta ttcaccactg cgcattgcag
    21361 cagtgactga ctttataatt gtactggcac tgctgatgct ctttttctgc ggcggcatga
    21421 aaacaacgtc gcttattttt gcttttattt gttgcgcggg attatttgcc ctttcagcac
    21481 cgctacaaat attgttacta caaaacgcca aaggcggaga gttattaggt gccgcaggtg
    21541 ggcaaatagc gtttaacctc ggtagcgccg tcggcgcata ttgcggaggt atgatgctga
    21601 cgctggggct ggcatataat tacgtggcgc tgcctgccgc cctgctttcg tttgctgcga
    21661 tgtcgtcgtt gctgctgtat ggtcgctata agcgccagca agcggcggat actccggtgc
    21721 tggcgaaacc actggggtag gttatagtct cggtgctcat tacttattgc cggatgcggc
    21781 gtgaacgcct tatccgccct acgcggttct ggcacatttt gcaggcctga taagacgcgg
    21841 caagcgtcgc atcaggcatc ggagcactta ttgccggatg cggcgtgaac gccttatccg
    21901 gcctacggtt ctggcacctt ttgtaggcct gataagacgc ggcaagcgtc gcatcaggca
    21961 tgatgcgcca attgcctacg ttttttactc ttgtggccat aaccacgcag cgccgcgtac
    22021 gccgctggaa tcaccgtgct tcgccttacg caccggcgtt tcacattcgc cgccgaagac
    22081 aaattgttta atcaactgcc caaccgtttg atataaacgg tctacattgc tcatcccgcc
    22141 ccccaggaca atcacatccg gatcgagaat attcacgaca tgtgccagcg attttgccag
    22201 ccgcagctcg tagcgacgca atgccagttc cgctaccgga tcgctttctt caaccaggcg
    22261 gataatttca ctgcctttca gcgcatgtcc gctcaaacga cgataatcca tcgcgaatcc
    22321 cgtgcccgaa ataaaggttt caatacaacc ttgtttaccg caataacaag ggacttcctc
    22381 gcgataacgc agttcgtctt cgtccatcca cggtagcgga ttgtgtcccc actcacctgc
    22441 cgtgccattg ccgccgatat gcgcccgccc attgaatgcc acgcccgcgc cgcatcccgt
    22501 gccgataatc acggcaaata ccgtctgcgc tcccgctgcc gcgccatcta ctgcttctga
    22561 aaccgccaga cagttagcgt catttgccag ccgcacttcc cgctgcaacc tcgcgcttaa
    22621 gtctttatcg aatggctgac cgttgagcca ggttgaattg gcattcttca ccacaccggt
    22681 gtaaggcgaa attgagccag gaatgcccat acctaccgtt ccgcgctgcc ccgtcgcctg
    22741 ctccgccata tcaaccaacg tggcgatcgt ttcaatagtc tgccggtaat catcacgcgg
    22801 cgtgggcaga cgatggcggt acaactgctc ccctgcatcg cccagtgcaa tcacttcagt
    22861 tttggtgccg cctaaatcga tacctatacg cacggtactc tccttatttt tttcaatatc
    22921 aatagcgtag agacggacaa ccggattggc aatgcaaggc cgccgacaat tcgttatcat
    22981 gcccgctaaa tttaacgaca aggccgtgga aattatcatg ctgtggttca aaaatttaat
    23041 ggtttaccgt cttagccgcg agatttcgct gcgtgcagaa gagatggaaa aacagctagc
    23101 ctcgatggca tttaccccat gcggcagcca ggacatggcg aagatgggct gggttcctcc
    23161 gatgggatcg cacagcgatg cgttaacgca cgttgccaat ggtcaaattg ttatctgcgc
    23221 gcgcaaagaa gaaaaaatcc tcccgtctcc ggtgattaaa caggcgctgg aagcgaaaat
    23281 cgccaaactg gaagcggaac aggcgcgtaa gctgaagaaa accgaaaaag attcgctgaa
    23341 agacgaagtg ctgcactctc tgctgccgcg tgctttcagc cgttttagcc agacaatgat
    23401 gtggatcgac acggttaacg gtttgattat ggtggactgc gccagtgcca aaaaagcgga
    23461 agatacgctg gcattactgc gtaaaagcct ggggtcgtta ccggttgtac cattgagcat
    23521 ggaaaacccg attgaactga cgctgaccga atgggttcgc tccggtagtg cggcacaggg
    23581 cttccagctg cttgatgaag ccgagctgaa atcgttgctg gaagatggcg gcgtgatccg
    23641 cgcgaagaaa caagatctga ccagcgaaga gatcaccaat cacattgaag ccggaaaagt
    23701 ggtgactaaa ctggcgctcg actggcagca gcgcattcag tttgtgatgt gcgacgatgg
    23761 ttcgctcaag cgtctgaagt tctgcgacga gctgcgcgat caaaacgaag atatcgaccg
    23821 tgaagatttc gcccagcgtt ttgatgccga tttcatcctg atgactggtg aactggcagc
    23881 gttaattcaa aacctgattg aaggattagg tggcgaagca caacgttaat tgctgatttt
    23941 cctttaatgc cggatgcgac gcctgccgcg tcttatccgg cgtacgaagc cacaccaggc
    24001 atataattat tcgctacggc gagcaataat ttttagcgca gcaatattat gcgttttacg
    24061 ctgtaacttg ctccatggac gttgtgtcat tgtttttcct caagccggtg acgcgcttca
    24121 ctgcgaattt tccgcgttgc cccggttttc actaaatcac gtaacagcga aagatcgggt
    24181 tgttcgacaa ataagagtaa tgatggatcc tcttttaacc acgccgtttt cacatcggca
    24241 gccagctgtg gattattaat agccagcgac cgatcctgag gctcagtcaa tgtcgttaac
    24301 aacaacgccg gggtatgtgc gttgcgcaat gccgtttggc gtaaatgatc attgcgactt
    24361 tgcagcaatg cacgccacca ttcatcatct gatttatctt ttatcgtagc cagttccgca
    24421 acaatatctg gagatcttca ctgatattta tatcaacctt gataaattat gaatatatcg
    24481 gaaattgaaa aaatcgcagc aaaggaaata ttattatggg ctaaagaaag gatatttcag
    24541 aaaaatgccc tcccgttcaa ggggaaggcg aggaattaca gatagcggca cagataagag
    24601 gtgggttcgg caacttgcag atgaaactca ctgtgaccgg gaacattaaa caccgaaccg
    24661 gcttcataca cctgccagtc ggtcgcgtca ggcagtaaca cattcagcgc gccactgatt
    24721 accgtcatct cttccggctc agcggtgctg aaggtgtatt cgccttcaac cataacaccc
    24781 acgctggcgc gaccagtgct gctgctggaa aagccgattg atttcacttt gccggaaaag
    24841 tactcattac tttgaagcat aaactggccc tgtttggtag ttgaacatct acttcactat
    24901 aggggccaga ggcgctggct gtcacgcaaa attacaccag taattccgca gccagccgtg
    24961 caatcaatac gttagacagc aagacaggaa catcgagctg tttttgcagt aaatcgcgat
    25021 gacgttggtg aaatcctaaa caatccagca tgatgacatc agcccctttt gccagtaatt
    25081 ctttcccggc atcaatgatt ttttgttctg aatcatgaat ggggttaccc aatgaaaata
    25141 ccggcgattt ctgcaaaatt tgccattttt gcgcctgaac gggcagcatc tcctcaaccg
    25201 gaacgataac ccccacctga tgatcttcaa caatagagga aaccagtgga ggcaatattc
    25261 gcgacggctc aagaaagatc gtattacgcg cagtcatact actaatgttt gctgtactca
    25321 ttaataaaat gacgtcataa ccctgattat cgagcacttc aaccacacct tgcaggtcac
    25381 gctccacttt gcgacgcgaa acatgggcca gctggttgtc atttaataat gtgagaatgg
    25441 tgtcttcgcc tgcttctggc gcgtactccg ccatcacttc ttcacgactt aacttcccca
    25501 gcaggctatg atgggaaata ttatcttcgt caatgtattc cgtcaggagc ggcaaaactt
    25561 cctgcatagg tacaatgccg atggtcagga tcgccaacga cgcactcatt gttcatccac
    25621 cttacttttc tttcgtcgtt aattaccggg caagtgtgaa gcaccactgc tgacacttac
    25681 ttgtgctaca aatgacaaaa agcgtagcag cagacgtgca cggcataatg taaagattcc
    25741 aaatgattcc agtaatggat tgttattgtt taatattcta attattagaa aaacatgaat
    25801 tatgaaaaat gtgacgcaga tcccttgtag tggcactcag aatcccttcc gagcagtctg
    25861 atgcggtcac tctttgtcag ggtcctcata gcgttttttc gcatccatcg cttcctgagc
    25921 ggtcggatgt tcactgatca acgagtctgg tttaggatga tcggctctga gttggtacca
    25981 ggttaccgtc tgtcctggct ttcctttttc aatcgtcact atatatgctt cacgaggata
    26041 aggcggtttc gttggcatcg ttcttcctta tttcacggga tgaacgttaa gtataggcgc
    26101 tcgaaaatca acaattgatc gtctgtgcca gggcgctgcg aatttcagaa atcacctggc
    26161 tgggttcgtt tgttgcgtcg atgataatat gcgcaacttc gcgatatagc gcatcgcgtt
    26221 cttccagcac ttcctgaact tcttcgctca gcggttttcc cgttaaggtt ggccgtaaat
    26281 cttcttccgg tgcagcttgc agtcggttaa ccaggactga tactggcgca cacaaataaa
    26341 ccacgatccc gttattttgc atgaagtgac gattaaattc cgtcagaata atgccgccgc
    26401 ctgtagcgat aacggtggat ggcgcagtta ccgcttccag cgccgccgtt tctctggcgc
    26461 gaaatcccgc ccactcttcc ctttcgacga tctccgcgac cgtcatattg agctgtgatt
    26521 gcaaccactg atcggtatcg acaaaccgac ggttaagcga atcggcaagg gccattccga
    26581 ccgttgtttt accacagccc cgaggcccga tcagaaaaag aggttgtgtc atcgtgggtt
    26641 ttccccaata ggtcgcaatg cggcgaaagc cggtgtcatg agaatagcga tcataccatc
    26701 aaactagtac aatttcgatt gtaaagaaaa aattccactt aaagtgaaaa tctcaatac
//
LOCUS       DACAOP010000058        26592 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.058, whole genome shotgun sequence.
ACCESSION   DACAOP010000058 DACAOP010000000
VERSION     DACAOP010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26592
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.058"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            310..4179
                     /locus_tag="IT892_002755"
     CDS             310..4179
                     /locus_tag="IT892_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter barrel domain-containing
                     lipoprotein"
                     /protein_id="HAP3135957.1"
                     /translation="MNRIYRVIWNCTLQVFQACSELTRRAGKTSTVNLRKSSGLTTKF
                     SRLTLGVLLALSGSASGASLEVDNDQITNIDTDVAYDAYLVGWYGTGVLNILAGGNAS
                     LTTITTSVIGANEDSEGTVNVLGGTWRLYDSGNNARPLNVGQSGTGTLNIKQKGHVDG
                     GYLRLGSSTGGVGTVNVEGEDSVLTTELFEIGSYGTGSLNITDKGYVTSSIVAILGYQ
                     AGSNGQVVVEKGGEWLIKNNDSSIEFQIGNQGTGEATIREGGVVTAENTIIGGNATGI
                     GTLNVQDQDSVITVRRLYNGYFGNGTVNISNNGLINNKEYSLVGVQDGSHGVVNVTDK
                     GHWNFLGTGEAFRYIYIGDAGDGELNVSSEGKVDSGIITAGMKETGTGNITVKDKNSV
                     ITNLGTNLGYDGHGEMNISNQGLVVSNGGSSLGYGETGVGNVSITTGGMWEVNKNVYT
                     TIGVAGVGNLNISDGGKFVSQNITFLGDKASGIGTLNLMDATSSFDTVGINVGNFGSG
                     IVNVSNGATLNSTGYGFIGGNASGKGIVNISTDSLWNLKTSSTNAQLLQVGVLGTGEL
                     NITTGGIVKARDTQIALNDKSKGDVRVDGQNSLLETFNMYVGTSGTGTLTLTNNGTLN
                     VEGGEVYLGVFEPAVGTLNIGAAHGEAAADAGFITNATKVEFGLGEGVFVFNHTNNSD
                     AGYQVDMLITGDDKDGKVIHDAGHTVFNAGNTYSGKTLVNDGLLTIASHTADGVTGMG
                     SSEVTIANPGTLDILASTNSAGDYTLTNALKGDGLMRVQLSSSDKMFGFTHATGTEFA
                     GVAQLKDSTFTLERDNTAALTHAMLQSDSENTTSVKVGEQSIGGLAMNGGTIIFDTDI
                     PAATLAEGYISVDTLVVGAGDYTWKGRNYQVNGTGDVLIDVPKPWNDPMANNPLTTLN
                     LLEHDDSHVGVQLVKAQTVIGSGGSLTLRDLQGDEVEADKTLHIAQNGTVVAEGDYGF
                     RLTTAPGNGLYVNYGLKALNIHGGQKLTLAEHGGAYGATADMSAKIGGEGDLAINTVR
                     QVSLSNGQNDYQGATYVQMGTLRTDADGALGNTRELNISNAAIVDLNGSTQTVETFTG
                     QMGSTVLFKEGALTVNKGGISQGELTGGGNLNVTGGTLAIEGLNARYNALTSISPNAE
                     VSLDNTQGLGRGNIANDGLLTLKNVTGELRNSISGKGIVSATARTDVELDGDNSRFVG
                     QFNIDTGSALSVNEQKNLGDASVINNGLLTISTERSWAMTHSISGSGDVTKLGTGILT
                     LNNDSAAYQGTTDIVGGGNCFRFRLCH"
     gene            4259..5071
                     /locus_tag="IT892_002756"
                     /pseudo
     CDS             4259..5071
                     /locus_tag="IT892_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368382.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            5954..6220
                     /gene="hipB"
                     /locus_tag="IT892_002757"
     CDS             5954..6220
                     /gene="hipB"
                     /locus_tag="IT892_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HipB"
                     /protein_id="HAP3135958.1"
                     /translation="MMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISN
                     FENNPDNTTLTTFFKILQSLELSMTLCDAKNASPESTEQQNLEW"
     gene            6220..7542
                     /gene="hipA"
                     /locus_tag="IT892_002758"
     CDS             6220..7542
                     /gene="hipA"
                     /locus_tag="IT892_002758"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system serine/threonine
                     protein kinase toxin HipA"
                     /protein_id="HAP3135959.1"
                     /translation="MPKLVTWMNNQRVGELTKLANGAHTFKYAPEWLASRYARPLSLS
                     LPLQRGNITSDAVFNFFDNLLPDSPIVRDRIVKRYHAKSRQPFDLLSEIGRDSVGAVT
                     LIPEDETVTHPIMAWEKLTEARLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTAL
                     LRIGNDWCIPKGITPTTHIIKLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVP
                     DAEIIKAGNVRALAVERFDRRWNAERTVLLRLPQEDMCQTFGLPSSVKYESDGGPGIA
                     RIMAFLMGSSEALKDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDII
                     SAFPVLGGTGIHISDLKLAMGLNASKGKKTAIDKIYPRHFLATAKVLRFPEVQMHEIL
                     SDFARMIPAALDNVKTSLPTDFPENVVTAVESNVLRLHGRLSREYGSK"
     gene            7854..8062
                     /locus_tag="IT892_002759"
                     /pseudo
     CDS             7854..8062
                     /locus_tag="IT892_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226947.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            8317..9543
                     /locus_tag="IT892_002760"
                     /pseudo
     CDS             8317..9543
                     /locus_tag="IT892_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310137.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
     gene            9557..10087
                     /locus_tag="IT892_002761"
     CDS             9557..10087
                     /locus_tag="IT892_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HAP3135960.1"
                     /translation="MKYNNIIFLGLCLGLTTYSALSADSVIKISGRVLDYGCTVSSDS
                     LNFTVDLQKNSARQFPTTGSTSPAVPFQITLSECSKGTTGVRVAFNGIEDAENNTLLK
                     LDEGSNTASGLGIEILDANMRPVKLNDLHAGMQWIPLVPEQNNILPYSARLKSTQKSV
                     NPGLVRASATFTLEFQ"
     gene            10100..10603
                     /locus_tag="IT892_002762"
     CDS             10100..10603
                     /locus_tag="IT892_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HAP3135961.1"
                     /translation="MKRLHKRFLLATFCALFTATLQAADVTITVNGRVVAKPCTIQTK
                     EANVNLGDLYTRNLQQPGSASGWHNITLSLTDCPVETSAVTAIVTGSTDNTGYYKNEG
                     TAENIQIELRDDQDAALKNGDSKTVIVDEITRNAQFPLKARAITVNGNASQGTIEALI
                     NVIYTWQ"
     gene            10662..11576
                     /locus_tag="IT892_002763"
     CDS             10662..11576
                     /locus_tag="IT892_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3135962.1"
                     /translation="MGKTISIKVLFGIYLLLMAGKVFAFSCNVDGGSSIGAGTTSVYV
                     NLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNN
                     VTYPFPLKTNTNVLDIGDKTPMPLPLKLYITPVGAAGGVVIKAGEVIARIHMYKIATL
                     GSGNPRNFTWNIISNNNVVMPTGGCTVDSRNVTVDLPDFPGSAEIPLGVYCSSEQKLS
                     FYLSGATTDSSRQVFANTAPDATKASGVGVTLMRNGKILATGENVSLGTVNKSKVPLG
                     LSATYGQTGNKVSAGTVQSVIGVTFIYE"
     gene            11910..14189
                     /gene="ydeP"
                     /locus_tag="IT892_002764"
     CDS             11910..14189
                     /gene="ydeP"
                     /locus_tag="IT892_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance putative oxidoreductase YdeP"
                     /protein_id="HAP3135963.1"
                     /translation="MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKP
                     EGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDKQVNASFFAENTVQSLLTWGDHE
                     LEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAA
                     FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHN
                     PGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYY
                     NVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEW
                     KDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNI
                     GKPGAGICPLRGHSNVQGDRTVGITEKPSAEFLARLGERYGFTPPHAPGHAAIASMQA
                     ICTGQARALICMGGNFALAMPDREASAVPLTQLDLAVHVATKLNRSHLLTARHSYILP
                     VLGRSEIDMQKNGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQAALPQS
                     VVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANF
                     ITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAK
                     ICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHD
                     PLSGIPGYKSIPVELEPSN"
     gene            14437..14634
                     /gene="safA"
                     /locus_tag="IT892_002765"
     CDS             14437..14634
                     /gene="safA"
                     /locus_tag="IT892_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system connector SafA"
                     /protein_id="HAP3135964.1"
                     /translation="MHATTVKNKITQRDNYKEIMSAIVVVLLLTLTLIAIFSAIDQLS
                     ISEMGRIARDLTHFIINSLQG"
     gene            14709..15470
                     /gene="ydeO"
                     /locus_tag="IT892_002766"
     CDS             14709..15470
                     /gene="ydeO"
                     /locus_tag="IT892_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response transcriptional regulator
                     YdeO"
                     /protein_id="HAP3135965.1"
                     /translation="MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPY
                     ERHFKEIGFTENTIKKYLQCTNIQTVTVPVPAKFLRASNVPTGLLNEMIAYLNSEERN
                     HHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCL
                     YISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYA
                     FRKHFGNSPKRVSKEYRCQSHTGMNTGNTMNALAI"
     gene            15872..17554
                     /locus_tag="IT892_002767"
     CDS             15872..17554
                     /locus_tag="IT892_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416015.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HAP3135966.1"
                     /translation="MKSALKKSVVSTSISLILASGMAAFAAHAADDVKLKATKTNVAF
                     SDFTPTEYSTKGKPNIIVLTMDDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKAI
                     EAAQKSTPTLLSLMDEGVRFTNGYVAHGVSGPSRAAIMTGRAPARFGVYSNTDAQDGI
                     PLTETFLPELFQNHGYYTAAVGKWHLSKISNVPVPEDKQTRDYHDNFTTFSAEEWQPQ
                     NRGFDYFMGFHAAGTAYYNSPSLFKNRERVPAKGYISDQLTDEAIGVVDRAKTLDQPF
                     MLYLAYNAPHLPNDNPAPDQYQKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQ
                     YDNTIILFTSDNGAVIDGPLPLNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKL
                     ISAMDFYPTALDAADISIPKDLKLDGVSLLPWLQDKKQGEPHKNLTWITSYSHWFDEE
                     NIPFWDNYHKFVRHQSDDYPHNPNTEDLSQFSYTVRNNDYSLVYTVENNQLGLYKLTD
                     LQQKDNLAAANPQVVKEMQGVVREFIDSSQPPLSEVNQEKFNNIKKALSEAK"
     gene            17606..18763
                     /locus_tag="IT892_002768"
     CDS             17606..18763
                     /locus_tag="IT892_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416014.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HAP3135967.1"
                     /translation="MHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIK
                     QYIAASGNQVYFTWQGGEPTLAGLDFFRKVIHYQQRYAGQKRIFNALQTNGILLNNEW
                     CAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQVEFNTLTVI
                     NNVNVHYPLEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAY
                     GKFMSTIFMQWVKNDVGEIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIY
                     ECDHFVYPQYKIGNINKSELKTMNSVQLTAQKKRIPAKCQQCAYKPICNGGCPKHRIT
                     KVNNETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYHIMDVAKQMENN"
     gene            complement(18729..18851)
                     /locus_tag="IT892_002769"
     CDS             complement(18729..18851)
                     /locus_tag="IT892_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135968.1"
                     /translation="MTKHPTGIYVGCLVKVIRRRLRMELKESVINYSPFVLQHP"
     gene            19054..20739
                     /locus_tag="IT892_002770"
     CDS             19054..20739
                     /locus_tag="IT892_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HAP3135969.1"
                     /translation="MITIPITLRMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILG
                     VVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPALLGIFVLISVNKTWLIKLLTIR
                     WREWLTDYYLNRWFADKNYYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQ
                     SLSMLITFTVILWESAGTLSFTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRP
                     LNVEKQRSEATFRTNLVQHNKQAELIALSNAESLQRQELSDNFHTIKENWHRLMNRQR
                     WLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKSRQAFMLVSNNLSWFIYKYDE
                     LAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVADASIRTPDNKIILENLNFHVSP
                     GKWLLLKGYSGAGKTTLLKTLSHCWPWFKGDISSPADSWYVSQTPLIKTGLLKEIICK
                     ALPLPVDDKSLSEVLHQVGLGKLAARIHDHDRWGDILSSGEKQRIALARLILRRPKWI
                     FLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPGVWNLADDICDISAVL"
     gene            20777..23149
                     /locus_tag="IT892_002771"
     CDS             20777..23149
                     /locus_tag="IT892_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HAP3135970.1"
                     /translation="MKRVLIPGVILCGADVAQAVDDKNMYMHFFEEMTVYAPVPVPVN
                     GNTHYTSESIERLPTGNGNISDLLRTNPAVRMDSTQSTSLNQGDIRPEKISIHGASPY
                     QNAYLIDGISATNNLNPANESDASSATNISGMSQGYYLDVSLLDNVTLYDSFVPVEFG
                     RFNGGVIDAKIKRFNADDSKVKLGYRTTRSDWLTSHIDENNKSAFNQGSSGSTYYSPD
                     FKKNFYTLSFNQELADNFGVTAGLSRRQSDITRADYVSNDGIVAGRAQYKNVIDTALS
                     KFTWFASDRFTHDLTLKYTGSSRDYNTSTFPQSDREMGNKSYGLAWDMDTQLAWAKLR
                     TTVGWDHISDYTRHDHDIWYTELSCTYGDITGRCTRGGLGHISQAVDNYTFKTRLDWQ
                     KFAVGNVSHQPYFGAEYIYSDAWTERHNQSESYVINAAGKKTNHTIYHKGKGRLGIDN
                     YTLYMADRISWRNVSLMPGVRYDYDNYLSNHNISPRFMTEWDIFANQTSMITAGYNRY
                     YGGNILDMGLRDIRNSWTESVSGNKTLTRYQDLKTPYNDELAMGLQQKIGKNVIARAN
                     YVYREAHDQISKSSRTDSATKTTITEYNNDGKTKTHSFSLSFELAEPLHIRQVDINPQ
                     IVFSYIKSKGNLSLNNGYEESNTGDNQVVYNGNLVSYDSVPVADFNNPLKISLNMDFT
                     HQPSGLVWANTLAWQEARKARIILGKTNAQYISEYSDYKQYVDEKLDSSLTWDTRLSW
                     TPQFLQQQNLTISADILNVLDSKTAVDTTNTGVATYASGRTFWLDVSMKF"
     gene            23194..25989
                     /locus_tag="IT892_002772"
     CDS             23194..25989
                     /locus_tag="IT892_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP3135971.1"
                     /translation="MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGL
                     RYMIYPHAHPKDQVNLWLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETF
                     ESMGLRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAE
                     RGVITEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQR
                     WYQPNNMTFIVVGDIDSKEALALIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDK
                     ENRVNGIALYYRLPMVQVNDEQSFIEQAEWSMLVQLFNQRLQERIQSGELKTISGGTA
                     RSVKIAPDYQSLFFRVNARDDNMQDAANALMAELATIDQHGFSAEELDDVKSTRLTWL
                     KNAVDQQAERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQL
                     RKNQDAFWEQMVNNEVAAKKALSPAAILALEKEYANKKLAAYVFPGRNLSLTVDADPQ
                     AEISSKETLAENLTSLTLSNGARVILAKSAGEEQKLQIIAVSNKGDLSFPAQQKSLIA
                     LANKAVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARTNNPEPGFQLIN
                     QRITHSTINDNIWASLQNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIA
                     QFTAADALAADRQLFSSPADITFVIVGNVAEDKLVALITRYLGSIKHSDSPLAAGKPL
                     TRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLPTRMALDAFNVALAKDLRVNIRE
                     QASGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQEL
                     NEYQQNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVK
                     QYLSHPVNTYTGVLLPK"
     gene            26351..>26592
                     /locus_tag="IT892_002773"
     CDS             26351..>26592
                     /locus_tag="IT892_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HAP3135972.1"
                     /translation="MDKKQVTDLRSELLDSRFGAKSISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSI"
BASE COUNT         7621 a         5740 c         6268 g         6963 t
ORIGIN      
        1 gggtttaata aacttcgatt tttagcaatt agtgctattc tttgttaaat atgatgatga
       61 taattttcct attgaaagaa acagttttct tattaagcaa caataactca tagttcatat
      121 ttaaataaaa taagaactat gcaattttta atctatcaat tcgaaagcat tagcaaatta
      181 gccaaattga caccttccca cctccaacta acactcaata cagacctctg acaatttaat
      241 aagtttcatt tttaatgtct gacgactcat ctctttcgtg gctgtattgt ttgtatatgg
      301 agcgtttata tgaatagaat ctatcgcgtg atatggaatt gcactctaca ggtatttcag
      361 gcctgctcgg aattaactcg cagggcaggt aaaacatcga cggttaattt gcgtaaatcc
      421 tctggactga caacgaaatt cagtagattg acgctgggtg ttttgctggc actaagcggt
      481 tcagcgtctg gtgcaagtct ggaagttgat aatgatcaga ttaccaatat tgatactgat
      541 gttgcttatg atgcctacct ggttggctgg tatggcactg gagtgcttaa tattttggct
      601 ggcggtaatg cctccttaac cactattact accagcgtca ttggcgctaa tgaggactca
      661 gagggcaccg ttaatgtttt gggtggcacc tggcgattgt atgatagcgg aaataatgca
      721 aggcctttaa atgtgggtca atccggaacg gggacgctga atattaaaca gaagggtcac
      781 gtcgatggag gctatttaag attaggttct tcgacaggag gcgtcgggac ggtcaatgtt
      841 gagggagagg actctgttct gacgaccgaa ttattcgaaa taggtagcta tggcacaggt
      901 tcattaaata ttacggataa gggttacgtc acgagttcaa tcgtcgccat tttaggctat
      961 caggcgggca gtaatggcca ggttgtcgtt gaaaagggtg gcgagtggct aataaaaaat
     1021 aatgattcct caattgaatt tcaaattggt aatcaaggaa ctggggaggc gactattcgc
     1081 gagggggggg tggttacggc tgaaaatacg attatcggtg gcaatgccac cggtatcgga
     1141 accctgaatg tgcaggatca agactctgtc atcacggtac gcagactcta taatggatat
     1201 ttcggtaatg gcacagtcaa tatttccaat aatggactga ttaataacaa agaatattca
     1261 ttggtgggcg ttcaggacgg ttcccacggt gtcgtcaacg tgaccgataa agggcattgg
     1321 aatttcctcg gaacgggcga agctttccgc tatatctata tcggtgatgc tggcgacggt
     1381 gaacttaatg tctcgagtga aggcaaagta gattcgggaa ttatcactgc ggggatgaaa
     1441 gaaacaggca caggcaacat tactgttaag gataagaact ccgttatcac taatctcgga
     1501 actaatcttg gttatgacgg ccacggcgaa atgaatatca gtaatcaggg gcttgttgtc
     1561 agcaacggag gaagttcact cggttatgga gaaaccggcg tcgggaatgt cagcatcacc
     1621 acggggggaa tgtgggaggt caataagaat gtctatacca ccattggtgt tgcgggcgtc
     1681 ggaaacctca atattagcga tggcggtaag ttcgtatcgc aaaatattac ttttttgggc
     1741 gataaagcaa gcggtatcgg cacactgaac ctgatggatg cgacatcatc gttcgatact
     1801 gtgggtatca atgtcggtaa ttttggtagc ggtatcgtaa atgtcagtaa tggtgccacc
     1861 cttaattcaa cgggctatgg atttatcgga ggaaatgcct ccggtaaggg gatagttaat
     1921 atttcaacgg acagtctctg gaatttaaag acatcatcta ctaacgcaca attgctacag
     1981 gtcggtgtat taggcacggg tgaactgaat attaccaccg gaggtatagt taaagcgcgt
     2041 gatacacaga tagctctcaa tgacaaaagt aagggcgacg tgagggtgga tgggcagaac
     2101 tctcttcttg aaacattcaa tatgtacgta gggacatctg gtacgggtac gttaaccctg
     2161 acgaataacg gtacgctgaa tgtcgaaggt ggagaagttt acttaggtgt ttttgagcct
     2221 gctgtaggaa cgctaaacat tggtgctgct cacggtgagg cggcggcaga tgccggattt
     2281 atcaccaatg cgacgaaagt ggagtttggt cttggcgaag gcgtttttgt ctttaatcat
     2341 accaataaca gtgatgccgg ctaccaggtc gatatgctga ttacaggtga cgataaagac
     2401 ggaaaagtga tccatgatgc aggccatacg gtgttcaatg cagggaatac ttatagcggt
     2461 aaaacgctgg tcaatgacgg cctcctgacc attgcgtctc atacggcaga tggggtaacg
     2521 ggcatggggt cgagtgaagt aaccattgca aaccccggta cgctcgacat tctcgcatca
     2581 acgaacagtg caggagatta cacgctgacc aatgcgctca aaggcgatgg cttgatgcga
     2641 gtgcagctgt catcctccga caagatgttt ggctttaccc atgcaacagg gactgaattc
     2701 gccggtgttg cccaactgaa agacagtacc ttcactctgg aacgcgacaa caccgctgcg
     2761 cttactcacg cgatgttgca gtctgacagt gaaaatacca catcggtaaa agttggagag
     2821 caatccattg gtggactggc catgaatgga ggtaccatca ttttcgatac ggatattcct
     2881 gctgcgacgc tcgcggaggg atatatcagc gtcgatacgc tggttgtcgg cgcgggtgac
     2941 tacacctgga aaggccgtaa ctatcaggta aacgggacgg gcgacgtgct tatcgacgtg
     3001 cctaaaccgt ggaatgatcc catggcgaat aaccctctga cgacgctcaa tttgctggaa
     3061 cacgacgata gccatgtcgg cgttcaactg gtgaaggcgc aaacggttat tgggtcgggt
     3121 ggctcattaa cgttacgtga tttacagggc gacgaggtgg aagcggacaa aacgttacac
     3181 attgcgcaaa acggaacggt ggtcgccgag ggtgattatg gattccgcct cacgaccgca
     3241 ccaggtaatg gtttgtacgt taactatggg ctgaaagcgc tgaacatcca tggtgggcaa
     3301 aagctgacgt tagccgaaca tggcggagcc tatggcgcaa cggccgatat gtcggcaaaa
     3361 atcggtggtg aaggggatct ggcaatcaat acggtgcgac aggtttcgct ttccaacggt
     3421 cagaacgact atcagggggc aacctacgtt cagatgggga cattacgtac cgatgcggat
     3481 ggtgcacttg gcaacacccg ggaactgaac atcagcaacg cggccatcgt cgatcttaat
     3541 ggatcgacgc agacggtaga gacattcacc gggcagatgg gttcgactgt tttgttcaaa
     3601 gagggggcgc tgacggtaaa taaaggtggg atcagtcagg gtgaactgac aggtggcgga
     3661 aacctgaatg ttacaggggg aacgctggct atcgaggggc ttaatgcacg ctacaatgcg
     3721 ttaaccagca ttagcccaaa tgcggaagtc agcctcgata atactcaggg gttaggcaga
     3781 ggaaatattg ccaatgacgg tctgttaacg ctaaaaaacg tgactggcga actgcgtaat
     3841 agcataagcg ggaagggtat cgtgagcgca accgccagga cagatgtaga gttggatggc
     3901 gataatagcc gctttgtggg gcaattcaac attgatacag gcagcgcgct cagcgtcaac
     3961 gagcagaaaa acctgggtga tgcttccgtt atcaataatg gcctgctcac catctccact
     4021 gagcgtagct gggcgatgac gcacagtatc agcggtagcg gtgatgtgac aaaactgggt
     4081 accgggatcc tgactcttaa caacgattcc gcggcgtatc agggtacgac ggatatcgtg
     4141 ggggggggaa attgctttcg gttccgactc tgccattaat atggcaagtc aacacattaa
     4201 tatccataac agcggtgtga tgtcgggaaa tgtcaccact gcaggtgata tgaacgttat
     4261 gcctgggggg gcactgcgtg tcgctaaaac cactatcggc ggcaacctgg agaatggcgg
     4321 cacggttcaa atgaatagcg aaggggggaa accggggaat gtactgaccg ttaacggcaa
     4381 ctataccgga aacaatggcc tgatgacgtt caacgcgacg ctgggcggcg ataattcgcc
     4441 caccgataag atgaacgtga aaggcgatac ccaagggaac actcgcgttc gggttgataa
     4501 cattggcggc gtcggtgcac aaacggtcaa cggtattgaa ctcattgagg ttggcggtaa
     4561 ttctgcaggt aacttcgcgc tgaccaccgg aactgtcgaa gctggggctt acgtctacac
     4621 gctggctaaa gggaagggga atgacgagaa aaactggtat ctgaccagta aatgggacgg
     4681 cgtaacgcca gcggatacac ccgatcccat caataatccc cctgttgtgg atccggaagg
     4741 cccatcagtt tatcgcccgg aggccggaag ctatatcagc aacattgccg cagccaactc
     4801 gctgtttagc catcgtttac acgaccgtct gggtgagccg cagtatacag attcactgca
     4861 ttctcagggg tcggcaagca gtatgtggat gcgtcatgtc ggagggcacg aacgttcaag
     4921 ggccggtgac ggtcagctaa atactcaggc taaccgctat gtattgcagc taggcggcga
     4981 tttggcgcag tggagtagca acgcgcagga tcgctggcat cttggcgtga tggcaggcta
     5041 cgccaatcag cacagtaata ctcagagtaa tcgtgtgggt tataaatcgg atgggcgcat
     5101 cagcggttac agcgctgggc tgtacgcgac ctggtatcag aacgatgcga ataagaccgg
     5161 cgcttatgtt gacagctggg cgctgtataa ctggtttgat aacagcgtca gttccgataa
     5221 ccgttctgct gacgactatg attctcgcgg tgtgacggcc tctgttgagg gtgggtatac
     5281 ctttgaagcg ggaacattta gcggcagcga agggacgctg aatacctggt acgtccagcc
     5341 acaggcgcaa atcacctgga tgggtgtgaa agattccgac catacccgga aagacggaac
     5401 gcgcattgaa acggaaggcg acggaaatgt gcaaacgcga cttggggtga aaacctacct
     5461 gaacagccat caccagcgtg acgatggtaa acagcgtgag ttccagcctt acattgaagc
     5521 gaactggatc aacaatagca aagtctacgc cgtgaagatg aatggtcaaa ccgtaggccg
     5581 tgaaggtgcg cgtaatctcg gtgaagtacg taccggggtt gaggcgaaag taaataacaa
     5641 ccttagcctg tgggggaatg tcggtgtgca actaggtgat aaaggctata gcgatactca
     5701 gggcatgctg ggagtgaaat atagctggta aaccgtataa gccgcatgtc gagatggcat
     5761 gcggcttaat attgccgact tcaaacggcg catcaacgcc ttatttaaat cctccttttt
     5821 atccgcgatc gcggatatcg cagcgtttat cccgtagagc ggataagatg tgtttccaga
     5881 ttgacttatc ctcactaaag gataaaactt ataatatccc cttaagcgga taaacttgct
     5941 gtggacgtat gacatgatga gctttcagaa gatctatagc ccaacgcaat tggcgaatgc
     6001 aatgaaactg gttcgccagc aaaatggctg gacgcagagc gagctggcga aaaaaattgg
     6061 tattaagcag gcgacgattt ccaatttcga aaacaaccct gacaatacca cgctcacgac
     6121 attttttaag attttacagt cgcttgaact ctcaatgacg ctatgcgacg cgaaaaatgc
     6181 ctcgccagaa tcaacagaac agcaaaatct ggagtggtaa tgcctaaact tgtcacttgg
     6241 atgaacaacc agcgggtagg cgagttaacg aagttagcca acggcgcgca cacctttaag
     6301 tatgcaccgg agtggttagc aagccgttat gccagaccgt tgtcactttc gctgccattg
     6361 cagaggggga atatcacctc tgatgccgta tttaacttct tcgataacct gttacccgat
     6421 agcccgattg tacgtgaccg gatcgttaaa cgttatcatg ccaaatccag acaaccgttt
     6481 gatttattgt cagaaatagg gcgagacagc gttggtgccg tgacgttaat acccgaagac
     6541 gaaaccgtaa cgcatccgat aatggcatgg gaaaagctta ctgaagccag acttgaagaa
     6601 gtattaacgg cttataaagc agatatcccg ctaggcatga ttagagaaga aaatgacttt
     6661 cgcatctcgg ttgctggcgc acaggagaag acagcactgc tcagaatagg caatgactgg
     6721 tgcattccga aaggaataac gccgacgacg cacatcatta aattaccgat tggcgaaatc
     6781 aggcagccca atgcgacgct cgatctcagc caaagcgttg ataatgagta ttactgtctg
     6841 ctgctggcga aagaacttgg gttgaatgtt ccggacgcag aaatcattaa agcgggaaat
     6901 gtgcgcgcgt tagcggtcga acgttttgac aggcgttgga atgctgagcg aacggtttta
     6961 cttcgcttgc cacaggagga tatgtgtcag acattcggtt taccttcatc ggtgaaatat
     7021 gaatcagatg gaggcccagg catcgcgcgg atcatggctt ttttgatggg gtccagcgag
     7081 gcgctgaaag atcgctatga ttttatgaaa ttccaggtct tccagtggtt gattggcgca
     7141 acggacggtc atgcaaaaaa cttctccgta tttattcagg ctggcggcag ttatcgactc
     7201 acgccatttt acgacatcat ttcagcattt ccggtccttg gcggtacggg aatacacatc
     7261 agcgatctca aactggcaat ggggcttaac gcatccaaag gcaaaaaaac ggcaatcgat
     7321 aaaatttatc cgcgacattt tttggcgaca gcaaaggtgc tgagattccc ggaagtgcag
     7381 atgcatgaaa tcctgagtga ctttgccaga atgattccag cagcactgga taacgtgaag
     7441 acttcattac cgacagattt tccggagaac gtggtgacgg cagttgaaag caatgtgttg
     7501 aggttgcatg gacggttaag ccgagaatac ggtagtaagt gagatatggg gtttggtcat
     7561 tgttaatgag catgacaatc atgaccgcca acgactggat tcttccttgg tttatattgg
     7621 tgcgcataat gtatattatg ttaaatcatg tctgagtgat gcgaagtgct tttctggtag
     7681 tcgttattcg ttcagggttc aagaacttaa gcctctcctc tttcataatt ggcctgtgca
     7741 tggagaaata gcctggttat tccctgcccc atgctaagag cgcagtgtct gtcgcataga
     7801 cactgcatac gaaaacacca gagggtgctg ttacttattt aaggacggat caagcgggaa
     7861 tgagtccact ccggtatcag aaatggctac gtctcaatga agtcaggcga cagatgctga
     7921 atgaacatta cgatgtcacc acagcagcct atgctgtcgg ttacgaaagc tatcccattt
     7981 cagtcgggaa tattcgcgga tgtttggaga gtcacccaag agagatatta ccaggttaag
     8041 aaagtctgtc ggacagcttt aataaaccct gcacttatct gtttagagca attcggtgtt
     8101 agtttcagca agcaaacatt aaccatagct aatgatttat agccatatta accattggta
     8161 gctcttgacc tttcctgaca cttcccttgt tcgcaataat attctgttta gtcacggttt
     8221 ataaataaca tgcataatga aatcgtcatg ttatttagcg acataaaatg tttttgcaaa
     8281 tactctcttc aacaagtgca gcaataaact tgttgtggaa ccaatatcca ggtcgcagga
     8341 tatcgctatt ctacgcaagg tttttataac ttatccgaca gtgcctacag tcgaatgagt
     8401 ggttacaccg tcaagcctcc taccggagac accaatgagc agacacaatt tattgattat
     8461 tttaatctgt tctacagtaa gcgtggtcag gaacaaataa gcatctctca gcagcttgga
     8521 aattacggta cgacattttt cagtgccagt cgccaaagtt actggaacac gtcacgcagc
     8581 gaccagcaaa tatcatttgg attaaatgtg ccgtttggtg atattacgac ttcgctgaat
     8641 tacagctatt ccaataatat atggcaaaac gatcgggatc atttactcgc ttttacgctt
     8701 aatgttccct tcagtcattg gatgcgtaca gacagtcagt cggcatttcg taattcaaac
     8761 gccagttaca gtatgtcaaa cgatttgaaa ggcggcatga ccaatctatc gggggtttat
     8821 ggcactctgc tgccggataa taacctgaat tatagcgttc aggtcggtaa cacccacgga
     8881 ggtaatacat cgtctggcac cagtggttac agttctctta attatcgtgg agcttatggt
     8941 aatactaatg tcggttacag tcggagtggt gacagcagcc agatttatta cggaatgagt
     9001 ggtgggatta ttgctcatgc tgatggcatc acctttggac agccgctggg cgacacaatg
     9061 gttctggtta aggctcctgg tgctgataat gtcaaaatag agaaccagac cggaattcat
     9121 accgactggc gtggctatgc catattacca tttgcgacag aatatagaga aaaccgtgtt
     9181 gctcttaacg cgaattccct tgcagataat gttgaactgg atgaaaccgt ggtcactgtc
     9241 atcccaactc acggtgctat tgccagagca acatttaatg cacaaatcgg cgggaaagta
     9301 ttaatgacgt tgaagtacgg taataagagc gttccattcg gtgcaattgt cacacacgga
     9361 gagaataaaa atggcagcat tgtcgcggaa aatggtcagg tttatctgac tggacttcca
     9421 cagtcagggc aattacaggt ttcatggggc aaagataaaa actcaaactg tattgtcgag
     9481 tacaagcttc ctgaagtttc tcctggtacc ttactgaacc agcagacagc aatctgtcgc
     9541 taaggaacaa tagattatga aatacaataa cattattttc ctcggtttat gtctggggtt
     9601 aaccacctat tctgctttat ccgcagatag cgttattaaa attagcgggc gcgtcctcga
     9661 ttatggctgc acagtctcat cggattcgct taattttacc gtagatctcc aaaaaaacag
     9721 tgccagacaa tttccaacga ccggtagcac aagtccagcc gtcccttttc agattacgtt
     9781 aagtgaatgc agcaaaggga caacgggggt tcgggttgca tttaacggta ttgaggatgc
     9841 agaaaataat actttgttga aactggatga aggaagcaat acggcctccg gtttgggtat
     9901 agaaatattg gacgcaaata tgcgtccggt gaaactgaat gatcttcatg ccgggatgca
     9961 gtggatccca ctggtaccag aacagaacaa tattttgcct tactccgctc gtctgaagtc
    10021 aactcagaag tccgtcaatc cgggactggt gagggcttcg gcaaccttta cccttgaatt
    10081 tcaataatca gagtcagata tgaaaagact tcacaagagg ttcctgttag ctacgttttg
    10141 cgcgttattc acagcaactc tccaggccgc cgatgtcact atcactgtta atggtcgggt
    10201 agtcgctaaa ccctgcacta ttcaaaccaa agaagctaac gttaatctcg gggatcttta
    10261 tacgcgcaat ctgcaacaac ctggttctgc atctggctgg cacaatatta ctttgtcatt
    10321 aaccgattgt ccggttgaaa caagtgcagt gacggcaatc gtgacaggtt caactgacaa
    10381 tacgggttat tacaaaaatg aaggtactgc cgaaaatatt cagatagagc tgagggatga
    10441 ccaggatgct gcgttaaaaa atggcgatag caaaacggtt attgttgatg agatcactcg
    10501 taatgcacag tttccactta aggcaagagc tatcacggtg aatggaaacg caagccaggg
    10561 aacgatcgag gcgctaatca atgtgatcta cacctggcaa taacgtcgat tcgattttct
    10621 tagccttctt tttaaatcaa tttttaacct taggatatat catgggtaaa acaatcagta
    10681 taaaggtcct gttcggtatt tatcttctat taatggcagg caaagttttt gccttcagtt
    10741 gtaatgtcga tggcgggtca agtattggag caggtacaac ctctgtttat gttaatctcg
    10801 accctgtaat acagccgggc cagaatctgg ttgtagactt gtctcagcat ataagttgct
    10861 ggaatgatta cggcggctgg tacgacactg atcatataaa cctggtacaa ggctcagctt
    10921 tcgcaggctc cctacagtca tataaaggat cgctgtactg gaataatgtg acctacccct
    10981 tcccgttgaa gacaaatacc aacgtattgg atattggtga taagacaccg atgccattac
    11041 cgttaaaact ctatattacc ccagttgggg cggccggtgg agttgtcata aaagcggggg
    11101 aagtcattgc ccgtattcat atgtataaaa ttgcaacatt aggaagcgga aatccgcgta
    11161 attttacgtg gaatattatt tcaaataaca atgttgttat gccaacaggc ggctgcaccg
    11221 ttgatagtcg taatgtcacc gtggatctcc cggactttcc tggaagcgca gaaatacccc
    11281 ttggcgtata ttgctcaagc gaacaaaagc tctcatttta tctttcgggt gccaccactg
    11341 acagtagccg acaagtgttt gctaacacag cacctgatgc aacaaaagca tcgggagtgg
    11401 gtgtcactct aatgcgtaat ggaaaaatac tggctacggg agaaaatgtc tccctgggga
    11461 cagtaaataa aagcaaagta cctctgggtt taagcgcaac ctatggacaa acaggaaaca
    11521 aggtttcagc cggaaccgtc cagtcagtca ttggtgtcac ttttatctat gaataattgt
    11581 gattttgacc ttagtctatg cgctccattc acgaaaattg cgcggataat tattttgtga
    11641 aggctattag cctacacctg taagaaaatc cgcgcacaat tgaagccaga gtcttatttt
    11701 ttatattgaa aaatatgtta atttaaacac tatgagagat gatgcttaac ttatcgtatt
    11761 taatctattg tttaacgata atagattaaa aatagaaaga gagtagtccc ctactcttat
    11821 atatccatgt tggcgataat ccctttgtat gtactgtgca tcatcgctat tacaaatcct
    11881 aataattcat ttccacacag gataagtaga tgaagaaaaa aattgaatcc taccagggtg
    11941 ctgcaggtgg ttggggtgct gttaaatccg tagcgaatgc agtacgtaag cagatggata
    12001 tacgccagga tgttattgcc atgtttgaca tgaataagcc agagggcttt gactgtccgg
    12061 gttgtgcatg gccagatcct aagcacagtg cgtcattcga catttgtgaa aacggcgcaa
    12121 aagcaatcgc ctgggaagtc acggataagc aggtaaacgc ctctttcttt gctgagaata
    12181 cggttcaatc attacttacc tggggagacc acgagcttga ggctgcgggg cgactcactc
    12241 agcctttgaa atatgatgcc gtcagcgact gttacaagcc attaagctgg caacaagctt
    12301 tcgacgaaat tggcgcacgc cttcaaagct atagtgatcc caatcaggtt gaattctata
    12361 cttcgggccg cacttccaat gaagctgcct ttctttatca gctttttgcc cgtgaatacg
    12421 ggagcaataa ctttcccgac tgctccaaca tgtgccatga accgacaagc gtgggtttgg
    12481 cagcgagtat cggtgtaggt aaagggaccg tgttgctgga agactttgag aagtgcgatt
    12541 tagtcatttg cattgggcat aaccctggta caaaccaccc tcgcatgctg acttcgttgc
    12601 gcgctttagt gaaacgggga gcgaaaatga tcgccatcaa tcctctacag gaacgtggcc
    12661 tggagcgatt taccgcaccg caaaacccgt ttgaaatgct gacgaactct gagactcagt
    12721 tggccagtgc ctactataac gtgcgcattg gtggcgatat ggcgttgctc aaggggatga
    12781 tgcgcctgtt aattgagcgc gatgatgctg caagcgccgc aggtcggcct tcattgcttg
    12841 atgacgagtt tattcaaacg cataccgtcg gctttgacga gctacgccgt gacgttctca
    12901 attccgagtg gaaagatatc gaacgtattt ctggactaag tcagacacaa atcgccgaac
    12961 tggctgacgc atatgccgct gccgaacgca ccattatctg ttacggaatg gggatcactc
    13021 agcacgaaca tggtacccag aacgtacagc aactggtcaa tctgctgttg atgaaaggta
    13081 acattggcaa gcctggtgcg ggtatctgcc cactacgtgg acactctaat gtacagggcg
    13141 accgaaccgt cggtatcacc gagaaaccgt ctgcagagtt tctggctcgt ctgggtgagc
    13201 gctatggctt caccccacct catgcacctg gacatgctgc aattgccagc atgcaagcaa
    13261 tatgtacggg gcaggctcga gcattgatct gcatgggggg caattttgcg ctggcaatgc
    13321 cagatcggga agcgagcgct gtaccgttaa cgcaattaga tttggcggta cacgtagcca
    13381 ctaagcttaa ccgctctcat ctgttgaccg cacggcatag ctatattctg ccggtcctgg
    13441 gacgtagcga gattgacatg caaaaaaacg gtgcgcaggc ggtaaccgtt gaggattcaa
    13501 tgtcgatgat tcatgcctcg cgtggcgtgt taaaacccgc cggtgtaatg ctgaaatcag
    13561 agtgtgcagt ggtcgcggga atcgcgcagg cagcactacc ccagagcgtg gtagcctggg
    13621 agtatctggt ggaagattat gatcgcattc gcaatgacat tgaagctgtg ctgccagagt
    13681 tcgccgacta taaccagcgc atccgtcatc ccggtggttt tcacctgata aatgcagctg
    13741 ctgaaaggcg ctggatgacg ccgtcaggta aggctaattt cattaccagc aaagggctgt
    13801 tagaagatcc ctcttcagcg tttaacagta agctggtcat ggcgacagta cgcagccacg
    13861 atcagtacaa cacgacgatt tatggtatgg atgatcgcta tcgaggggta ttcggtcaac
    13921 gagatgtggt ctttatgagt gctaaacaag ctaaaatttg ccgtgtaaaa aacggcgaaa
    13981 gagttaatct tattgcgctt acgccagacg gtaagcgcag ctcacgccgc atggatagat
    14041 taaaagtggt catttaccct atggctgacc gctcactggt gacctatttt ccagaatcga
    14101 atcacatgct aacacttgat aaccacgatc cattaagtgg cattcctggc tataaaagta
    14161 ttccggttga attagaacca tcaaattaat gcctcttctc atttcttctg ctgtcatccg
    14221 cacagcagaa gaattcctca ttgactatta tttcgcaatt tgctcacatg gattaaatta
    14281 aactacatac tataagatat aaacttctgc ctacagctgt aagaaactcc gctcagtact
    14341 gaagcaccag tcctatttcc tcttttctcc agcctgttat attaagcata ctgattaacg
    14401 atttttaacg ttatccgcta aataaacata tttgaaatgc atgcgaccac agtgaaaaac
    14461 aaaatcacgc aaagagacaa ctataaagaa atcatgtctg caattgtggt tgtcttatta
    14521 ctgacactta cgttgatagc cattttttcg gcaattgatc agctgagtat ttcagaaatg
    14581 ggtcgcattg caagagatct tacacatttc attatcaata gtttgcaagg ctgaaaacaa
    14641 acagcaaatt ataaatatga aatgttaaaa aagtatcgat aaaaacttta ttgttttaag
    14701 gagataaaat gtcgctcgtt tgttctgtta tatttattca tcatgccttc aacgctaaca
    14761 ttttagataa agattacgcc ttctctgacg gcgagatcct gatggtagat aacgctgttc
    14821 gtacgcattt tgaaccttat gagcggcatt ttaaagagat cggatttact gaaaatacca
    14881 ttaaaaaata tctacaatgc actaacatcc agacagtgac ggtgcctgtt cctgcgaagt
    14941 ttttacgtgc ttcaaatgta ccgactggat tgcttaatga aatgattgct tatctcaact
    15001 cggaagaacg caatcatcat aatttttcag aacttttgct tttttcttgc ctgtctattt
    15061 ttgccgcatg caaaggtttc attacactat taactaacgg tgtgctatcc gtttctggga
    15121 aagtgagaaa tattgtcaac atgaagctgg cgcacccatg gaagctgaaa gatatttgtg
    15181 actgcctgta catcagtgaa agcctgttga agaaaaaact taagcaagag caaacgacat
    15241 tctcacagat tcttttagat gcaagaatgc agcacgcaaa aaatttgata cgcgtagaag
    15301 gttcagtcaa taaaattgcc gaacaatgtg gttatgccag tacatcttat tttatttatg
    15361 cgttccgcaa acatttcggc aacagtccga agagagtttc taaggagtac cgttgtcaaa
    15421 gtcacacggg tatgaatacg ggcaacacga tgaatgcttt agctatttga ttatttgcta
    15481 acgagtagtc aaccacacac gctgcgtaag aattaaatgg ggcagccatt ccctgccccg
    15541 cgttgttttt aggcgatata tttattgaaa taaataagtg acatccatca catatttatg
    15601 cacttgcata acctgttgca tgattattta tgatctcaat tctgcatttt gtcagtaaaa
    15661 tgcaataatt tattaaatat caataaatta gttgtttatc ggcgagaaat tacttaatag
    15721 aacagaaagt aatgtcaacg ctttatggac tgttttttcc ctttttttag ctaaatctgc
    15781 tatctcttta tgtgactaac ttcacttaca tccacttatt tctcttcgta aaattacttt
    15841 ggaattaagt acaataagaa gaggaacatt tatgaagtct gcattaaaga aaagtgtcgt
    15901 aagtacctcg atatctttga tactggcatc tggtatggct gcatttgctg ctcatgcggc
    15961 agatgatgta aagctgaaag caaccaaaac aaacgttgct ttctcagact ttacgccgac
    16021 agaatacagt accaaaggaa agccaaatat tatcgtactg accatggatg atcttggtta
    16081 tggacaactt ccttttgata agggatcttt tgacccaaaa acaatggaaa atcgtgaagt
    16141 tgtcgatacc tacaaaatag ggatagataa agccattgaa gctgcacaaa aatcaacgcc
    16201 gacgctcctt tcattaatgg atgaaggcgt acgttttact aacggctatg tggcacacgg
    16261 tgtttccggc ccctcccgcg ccgcaataat gaccggtcga gctcccgccc gctttggtgt
    16321 ctattccaat accgatgctc aggatggtat tccgctaaca gaaactttct tgcctgaatt
    16381 attccagaat catggttatt acactgcagc agtaggtaaa tggcacttgt caaaaatcag
    16441 taatgtgccg gtaccggaag ataaacaaac gcgtgactat catgacaact tcaccacatt
    16501 ttctgcggaa gaatggcaac ctcaaaaccg tggctttgat tactttatgg gattccacgc
    16561 tgcaggaacg gcatattaca actccccttc actgttcaaa aatcgtgaac gtgtccccgc
    16621 aaaaggttat atcagcgatc agttaaccga tgaggcaatt ggcgttgttg atcgtgccaa
    16681 aacacttgac cagcctttta tgctttacct ggcttataat gctccgcacc tgccaaatga
    16741 taatcctgca ccggatcaat atcagaagca atttaatacc ggtagtcaaa cagcagataa
    16801 ctactacgct tccgtttatt ctgttgatca gggtgtaaaa cgcattctcg aacaactgaa
    16861 gaaaaacgga cagtatgaca atacaattat tctctttacc tccgataatg gtgcggttat
    16921 cgatggtcct ctgccgctga acggggcgca aaaaggctat aagagtcaga cctatcctgg
    16981 cggtactcac accccaatgt ttatgtggtg gaaaggaaaa cttcaacccg gtaattatga
    17041 caagctgatt tccgcaatgg atttctaccc gacagctctt gatgcagccg atatcagcat
    17101 tccaaaagac cttaagctgg atggcgtttc cttgctgccc tggttgcaag ataagaaaca
    17161 aggcgagcca cataaaaatc tgacctggat aacctcttat tctcactggt ttgacgagga
    17221 aaatattcca ttctgggata attaccacaa atttgttcgc catcagtcag acgattaccc
    17281 gcataacccc aacactgagg acttaagcca attctcttat acggtgagaa ataacgatta
    17341 ttcgcttgtc tatacagtag aaaacaatca gttaggtctc tacaaactga cggatctaca
    17401 gcaaaaagat aaccttgccg ccgccaatcc gcaggtcgtt aaagagatgc aaggcgtggt
    17461 aagagagttt atcgacagca gccagccacc gcttagcgag gtaaatcagg agaagtttaa
    17521 caatatcaag aaagcactaa gcgaagcgaa ataactaaac cttcatgcgg cggatttttc
    17581 cgccgcctta ttgagcgaga tagcgatgca cgttacagcc aagccctcca gttttcaatg
    17641 taatctcaaa tgtgattact gtttttacct tgaaaaagag tcgcagttta ctcatgaaaa
    17701 atggatggat gacagcactc tgaaagagtt catcaaacaa tatatcgcag cgtctggcaa
    17761 tcaggtctat tttacctggc aaggcggtga acccactctg gctggcctgg attttttccg
    17821 taaagttatt cactatcaac aacgctatgc aggccaaaaa cgtattttta atgcattaca
    17881 aacgaatggc attttattga ataatgaatg gtgtgccttt ctcaaagaac atgaatttct
    17941 ggttggtatc tcgatcgatg gcccccagga gttacatgac cgttacagac gcagtaattc
    18001 aggtaacggt acttttgcaa aagtgatagc agccatcgag cgtctgaaat catatcaagt
    18061 agagtttaat acgttaaccg tcattaataa cgttaatgtc cattaccctc ttgaggttta
    18121 tcatttttta aaatctatcg gcagtaaaca tatgcaattt atcgaattgc tagaaaccgg
    18181 gacgccgaat attgatttca gtggtcatag tgagaacaca ttccgtatca ttgatttttc
    18241 tgtgcctccc acggcttatg gcaagtttat gtcaaccatt tttatgcaat gggttaaaaa
    18301 cgatgtgggt gaaattttca tccgtcagtt tgaaagcttt gtcagccgtt ttttggggaa
    18361 tgggcatacc agttgtattt tccaggagtc ctgcaaggat aatctggttg ttgaaagtaa
    18421 tggagacatt tacgaatgcg accattttgt ctatccacag tacaaaattg gaaacattaa
    18481 taaatctgaa ctcaaaacga tgaacagtgt acaactgaca gcgcaaaaaa aacggattcc
    18541 agcgaaatgt cagcaatgtg catataaacc tatctgcaat ggcggttgtc ctaagcatcg
    18601 tattactaaa gtaaacaatg agactgtttc ttatttttgc gaaggttata aaatcctttt
    18661 ttcaaccatg gtaccttata tgaacgccat ggtagagtta gctaagaaca gagtaccgct
    18721 ttaccacatt atggatgttg caaaacaaat ggagaataat taataacgct ctcttttaac
    18781 tccattctta gcctccttct tatgacctta acaaggcacc cgacataaat tcctgtcggg
    18841 tgtttcgtca tcatcatctt cccttgcgaa aatcctggct tacgtggtat gcatcagggc
    18901 attagcaata tccttgatta tcaatagcat aaccataacc actgaaaatg aaatattcct
    18961 ttatatttca tattgttaaa tgatacttaa ataaatttca tcagtaaatc attgccatag
    19021 ataatcattg gatggcacaa tcaattttcg ctaatgataa ccattcccat tacgcttcgt
    19081 atgttgatag caaagtatct ctgtctgttg aagccctttt ggctgcgtaa gaataataaa
    19141 acttcagtgt tgttaatcat tattatcctc gccatgatcc ttggcgtggt taaaattcag
    19201 gtctggttaa acgactggaa taatgatttt ttcaatgcgc taagccagaa agaaaccgat
    19261 aagctttggc agcttgtcct ttggttccct gccctgctgg ggatctttgt attaatatcc
    19321 gtaaacaaaa catggttaat taaactactg actattcgct ggcgcgaatg gttaacagat
    19381 tactacctta atcggtggtt tgcagataaa aactactact tcacgcagat ctacggcgag
    19441 cataaaaata cagataaccc tgaccaacgt atcgctgaag acattctctt actgatcagc
    19501 aaaacgctca gtctttcatt tggcttcatc cagtcactta gcatgctgat cacctttacc
    19561 gttattcttt gggaaagcgc gggtacgctc tcattcactg ttggtggaac agaatggaat
    19621 atccaggggt atatggtcta taccgtcgtg ctcattgtga tcggtggaac tttatttacc
    19681 cataaggtgg gtaaacgtat tcgtccgctt aatgtggaaa aacaacgtag cgaagcgaca
    19741 tttcgaacaa atcttgtgca gcataataag caggcagaac tgattgcgct aagcaatgct
    19801 gagtctctac aacgccagga gttgagcgac aattttcata ccattaaaga gaactggcat
    19861 cgtttaatga atcgtcagcg gtggcttgat tactggcaga atatttattc gcgctcgctt
    19921 agcgttcttc cctactttct gttattgccg cagtttatta gcgggcagat caatctgggc
    19981 ggactgatga aatcgcgcca ggcatttatg ctggtatcga acaatttaag ctggtttatt
    20041 tataaatatg acgaacttgc tgaactggct gcggttatcg atcgcttgta tgagttccat
    20101 caactcactg aacagcgccc tacgaataag cctaaaaatt gccaacatgc ggtacaagtg
    20161 gctgatgcga gtattcgtac gcctgataat aagatcatat tagagaacct gaactttcat
    20221 gtttcgccag gcaaatggct attactgaaa ggctactctg gcgcgggaaa aaccacactg
    20281 cttaaaacat tatcccactg ctggccgtgg tttaaaggtg atatttcttc tcctgctgac
    20341 agttggtatg tgtcacaaac accgttaatc aaaaccggct tactgaaaga gattatttgt
    20401 aaagcacttc ccctgcccgt agacgataaa tcgttgagcg aagtactgca tcaggttggt
    20461 cttgggaaat tggctgcgcg tattcatgac cacgatcgct ggggagatat tctttccagc
    20521 ggcgaaaaac aacgtatcgc cctggcacga ttaattttac gacgtccgaa atggatattt
    20581 cttgacgaaa ctacctctca tcttgaggaa caagaggcta tccgcttact gcgtttagtg
    20641 cgtgaaaaac tacccacaag cggcgtcatt atggttacac atcaacccgg tgtctggaac
    20701 ctggccgatg atatttgtga cattagcgcg gttttataaa aacaataaaa gccctgctgt
    20761 acggagatat aaataaatga agcgagttct tattcctggc gtcattttat gtggcgctga
    20821 tgtggcgcag gccgtcgatg acaaaaacat gtacatgcat ttttttgaag agatgacggt
    20881 ctatgctcct gtccctgtac ccgtaaacgg caacacgcat tacaccagtg aaagcatcga
    20941 gcgtttaccg accgggaatg gcaatatcag cgatctgctg agaaccaacc ctgcggtacg
    21001 catggattca acgcaaagta cctcgttgaa ccagggagat attcgccctg agaaaatctc
    21061 tattcacggt gcgtcgccct accagaatgc ctatttgatt gacggtatta gtgcaactaa
    21121 taacctgaac ccagcgaatg agtccgatgc cagtagtgca accaatatta gcgggatgtc
    21181 acaggggtat tatcttgatg tcagcttact ggacaatgtg acgctttatg acagttttgt
    21241 gccggttgaa tttggtcgct tcaatggcgg ggtaattgat gcaaagatca aacgcttcaa
    21301 cgctgatgat agcaaggtga aattgggtta tcgcactacg cgttcggact ggttaacatc
    21361 gcatatcgat gagaataaca agagcgcatt taatcaaggc tcttcaggaa gtacttatta
    21421 ctccccagat tttaaaaaga acttttatac cttgtcgttt aatcaggaac tcgctgataa
    21481 cttcggcgtt accgccggtt tatcgcgccg ccagtctgat atcacccgcg cggattatgt
    21541 ttcgaatgac ggcattgtcg ccggtcgggc acagtataaa aacgttatcg atactgcatt
    21601 aagcaaattt acctggtttg ccagcgaccg ctttacccac gatttaacct taaaatatac
    21661 cggctccagc cgtgattata ataccagcac cttcccgcag tctgatcgcg aaatgggtaa
    21721 taaatcctat ggtctggcat gggatatgga tacgcagctc gcatgggcca aactgcgtac
    21781 caccgttggt tgggatcata ttagtgatta tacccgtcac gatcatgaca tctggtacac
    21841 cgaactttca tgtacatatg gtgatattac agggcgttgc acccgtggcg gattaggaca
    21901 catttcccag gctgtagata attacacctt caaaacacgc ctggactggc aaaaattcgc
    21961 cgtgggtaat gtttcgcatc aaccctactt cggcgcggaa tacatctatt ccgatgcgtg
    22021 gactgaacgc cataaccagt ctgaatccta tgtgattaat gctgccggaa agaaaactaa
    22081 ccataccatt taccataaag gtaaaggccg cctgggaatt gacaactaca cgctgtatat
    22141 ggcggatcgc attagctggc gtaatgtgtc attaatgccc ggcgtgcggt atgactatga
    22201 caactatctg tcaaaccaca atatctcccc gcgctttatg acggaatggg atatttttgc
    22261 taatcaaacc tcaatgatta cagcaggtta taaccgttac tatggcggga atattcttga
    22321 tatgggatta cgtgatatcc gcaatagctg gacggaatcg gtatcaggta ataaaactct
    22381 gacgcgttat caggatttga aaacgcctta taacgatgaa ctggcaatgg gattgcagca
    22441 gaaaatcggt aagaacgtta ttgcgcgtgc aaactatgtt taccgtgaag cgcatgatca
    22501 aatcagcaaa agcagtcgta ccgacagcgc gactaaaacc accattactg aatataacaa
    22561 cgatggcaaa accaaaacgc attcgttcag cctcagtttt gaactggccg aacccctgca
    22621 tatccgccag gtagatatta acccacaaat tgtctttagc tatatcaaga gcaagggcaa
    22681 cttgtcgtta aacaatggtt atgaggagag caataccggt gataaccagg tggtttataa
    22741 cggtaatctg gtctcttacg atagcgttcc agtggcagat tttaataacc cattaaagat
    22801 ctccttaaac atggatttca cgcatcaacc gagcgggtta gtgtgggcga atacgctggc
    22861 ctggcaagaa gcgcgtaaag ctcgcattat ccttggtaag acaaatgcgc aatacatcag
    22921 cgaatattca gattacaagc agtatgttga cgaaaaactg gatagcagcc tgacctggga
    22981 cacccgcttg tcctggacgc cacaatttct gcaacaacaa aacctgacga tcagtgccga
    23041 tattctcaat gtactggata gcaaaaccgc tgttgataca acgaacaccg gtgtggcgac
    23101 ctacgccagt ggccgtactt tctggcttga tgtcagcatg aaattttaat agttcggatt
    23161 ttacttaacc gggtaaattc gcccggtttt cgcatggaga taattatgag aaacctctgt
    23221 ttcttactga cgttagtggc aactctgttg ctccccgggc ggctgattgc cgccgcctta
    23281 ccgcaggatg aaaagttaat taccgggcaa ctggacaatg gcttgcgata tatgatttat
    23341 ccgcatgctc atccaaagga tcaggtaaat ttatggctgc aaattcatac cggttcattg
    23401 caggaagaag acaatgagcg cggcgtggct cattttgtag aacatatgat gtttaacggc
    23461 acaaaaacat ggccgggtaa taaagtcatc gaaacatttg agtcaatggg cctgcgtttt
    23521 ggtcgcgatg ttaatgccta taccagctat gacgaaacgg tgtatcaggt gagtttgccg
    23581 actacgcaga aacaaaatct gcaacaagtg atggcaatct tcagtgaatg gagtaatgcc
    23641 gcaacctttg aaaaactcga agtagacgct gaacgtggcg taattactga ggaatggcgt
    23701 gcccatcagg atgcgaaatg gcgcacctct caggcgcgcc gccctttcct gctggcaaat
    23761 acccgtaatt tagaccgtga acctatcggc ctgatggata ctgtcgccac ggtcacaccg
    23821 gcacaattgc gccaatttta tcaacgctgg tatcaaccaa ataatatgac ctttatcgtg
    23881 gtcggcgata tcgacagtaa agaagcgctg gcgctgataa aggataattt aagtaagctt
    23941 ccggctaaca aagcagctga aaatcgcgtc tggccgacaa aagccgaaaa ccacctgcgc
    24001 tttaatatca ttaatgataa agaaaaccgg gtgaacggca tcgcactcta ttatcgcctg
    24061 ccaatggtac aagtgaacga tgagcaaagc tttatcgaac aagctgaatg gagcatgtta
    24121 gttcagctgt tcaatcaacg tctgcaggaa cgcatacagt cgggcgagtt gaagactatt
    24181 tctggcggca ctgcgcgcag cgttaaaatt gcacccgatt atcagtcgct gtttttccgt
    24241 gtaaatgcac gagacgataa tatgcaggat gctgcgaatg cattaatggc agagttggca
    24301 accattgatc agcatggttt ttctgctgaa gaactcgatg atgtcaaatc tacccgcctc
    24361 acctggctga aaaatgcggt tgatcagcaa gctgaacgtg atttacgtat gctgaccagt
    24421 cgcctggcat ccagctcatt aaataatacg ccgttcttgt cgccggaaga gacatatcaa
    24481 ctttcgaaac gtctgtggca gcaaattacc gtgcaaagtc tggcggaaaa atggcagcag
    24541 ttaagaaaga accaggacgc attttgggag caaatggtaa acaatgaggt tgccgccaaa
    24601 aaagcattgt ctcctgcggc tatcctggcg ctggaaaagg agtacgccaa caaaaagctg
    24661 gcggcttacg tcttcccagg cagaaattta tcgttaacag tagacgcaga cccacaggcg
    24721 gaaattagca gcaaagaaac gctggcggag aatctgacat cattaacact ttccaatggt
    24781 gccagggtta ttctggcaaa atccgcgggt gaagagcaaa agctacaaat tattgccgta
    24841 tcgaataaag gcgatttaag tttccctgcg cagcaaaaat cacttatcgc gctggcaaat
    24901 aaagcagtta gcggaagcgg cgttggcgaa ctctcctctt ccagcctgaa acgctggagt
    24961 gcggaaaatt cggtaaccat gagcagtaaa gtcagtggca tgaatacgtt gctctccgtt
    25021 agcgcgcgga ctaataaccc tgaacctggt tttcagttga ttaaccagcg aatcacccac
    25081 agcacgatta acgataatat ttgggcatcg ctacaaaatg ctcaaattca ggcgttgaaa
    25141 acgctcgacc agcgtccagc ggagaaattc gcccagcaga tgtatgagac gcgctatgct
    25201 gatgaccgca cgaaattact gcaagaaaat cagattgcac agtttactgc cgcagatgcg
    25261 ctggctgccg atcgccaatt gttttcatct ccagcggata tcacgtttgt cattgtcggt
    25321 aatgtcgcag aagacaaact cgtggcgtta attacgcgtt acttaggatc aatcaaacac
    25381 tctgattcgc cattagccgc aggtaaacca ttaactcgcg cgacggacaa cgcatcggtt
    25441 actgtaaaag aacaaaatga acctgtggca caggtttcac agtggaagcg ttatgattcc
    25501 cggacacctg ttaatctgcc gacgcgtatg gcgctcgatg cttttaacgt cgcactggca
    25561 aaagatctac gtgttaatat tcgtgaacag gcatctggag catacagcgt ttcttctcgc
    25621 ctctcggttg atcctcaggc caaagatatc agtcatttgc tggcttttac ttgtcaacca
    25681 gaacgacatg atgaactgtt aacgttagcg aatgaagtga tggttaagcg tctggctaaa
    25741 gggatcagtg agcaagaact gaatgaatac cagcaaaacg ttcagcgcag cctcgatatc
    25801 caacagcgta gcgttcaaca attagcgaac actattgtaa atagtcttat tcaatatgac
    25861 gatcctgcag catggactga gcaggagcaa ttgttgaaac aaatgacggt agagaatgtt
    25921 aacactgccg ttaaacaata tctttctcat ccggtaaata cttataccgg agtattattg
    25981 ccaaaataat aacagccccg tcaacacatc gttggcgggg attttagcaa tattcgctat
    26041 ttttatgtaa taattttata aatgcgttca aaataataat caagtactaa tagtgatatt
    26101 ttaaggtctg atttttacgt gataattcag gagacacaga atgcgcataa aaataacagc
    26161 ataaaacacc ttgccaccac ccaagaattt catattgtat tgtttttcaa tgaaaaaata
    26221 ttattcgcgt aatatctcac gataaataac attaggattt tgttatttaa acacgagtcc
    26281 tttgcacttg cttactttat cgataaatcc tactttttta atgcgatcca atcattttaa
    26341 ggagtttaaa atggataaga agcaagtaac ggatttaagg tcggaactac tcgattcacg
    26401 ttttggtgcg aagtctattt ccactatcgc agaatcaaaa cgttttccgc tgcacgaaat
    26461 gcgcgacgat gtcgcattcc agattatcaa tgacgaatta tatcttgatg gcaacgctcg
    26521 tcagaacctg gccactttct gccagacctg ggacgacgaa aatgtccaca aattgatgga
    26581 tttatccatt aa
//
LOCUS       DACAOP010000059        26562 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.059, whole genome shotgun sequence.
ACCESSION   DACAOP010000059 DACAOP010000000
VERSION     DACAOP010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26562
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.059"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            48..167
                     /gene="hemP"
                     /locus_tag="IT892_002774"
     CDS             48..167
                     /gene="hemP"
                     /locus_tag="IT892_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HAP3135973.1"
                     /translation="MRRISSQTLLGPDGKLIIDHDGQEYLLRKTQAGKLLLTK"
     gene            complement(171..1607)
                     /locus_tag="IT892_002775"
     CDS             complement(171..1607)
                     /locus_tag="IT892_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HAP3135974.1"
                     /translation="MTLSFVTRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIP
                     SSLFKNGAGVWGGEALLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTM
                     DWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRE
                     TAEPGAMLMRVAPSHLRFGHFEHFYYRRESEKVRQLADFAIRHYWSHLADDEDKYRLW
                     FSDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSD
                     HQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGERMRQKLG
                     FMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDW
                     FARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEAL
                     RNPFSDRDDDYVSRPPDWGKRLEVSCSS"
     gene            complement(1670..2383)
                     /gene="ydiV"
                     /locus_tag="IT892_002776"
     CDS             complement(1670..2383)
                     /gene="ydiV"
                     /locus_tag="IT892_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-FlhDC factor"
                     /protein_id="HAP3135975.1"
                     /translation="MKIFLENLYHSDCYFLPIRDNQQVLVGVELITHFSSEDGTVRIP
                     TSRVIAQLTEEQHWQLFSEQLELLKSCQHFFIQHKLFAWLNLTPQVATLLLERDNYAG
                     ELLKYPFIELLINENYPHLNEGKDNRGLLSLSQVYPLVLGNLGAGNSTMKAVFDGLFT
                     RVMLDKSFIQQQITHRSFEPFIRAIQAQISPCCNCIIAGGIDTAEILAQITPFDFHAL
                     QGCLWPAVPINQITTLVQR"
     gene            complement(2630..3094)
                     /locus_tag="IT892_002777"
     CDS             complement(2630..3094)
                     /locus_tag="IT892_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HAP3135976.1"
                     /translation="MRFCLILITALLLAGCSHHKAPPPNARLSDSITVIAGLNDQLQS
                     WHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPRETKQQASIGTQIDKDELLPGDL
                     VFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI"
     gene            complement(3172..3921)
                     /gene="btuD"
                     /locus_tag="IT892_002778"
     CDS             complement(3172..3921)
                     /gene="btuD"
                     /locus_tag="IT892_002778"
                     /EC_number="7.6.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter ATP-binding protein
                     BtuD"
                     /protein_id="HAP3135977.1"
                     /translation="MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLA
                     RMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKT
                     RTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEP
                     MNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRRE
                     EVLTPPNLAQAYGMNFRRLDIEGHRMLISTI"
     gene            complement(3921..4472)
                     /gene="btuE"
                     /locus_tag="IT892_002779"
     CDS             complement(3921..4472)
                     /gene="btuE"
                     /locus_tag="IT892_002779"
                     /EC_number="1.11.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional thioredoxin/glutathione peroxidase"
                     /protein_id="HAP3135978.1"
                     /translation="MQDSILTTVVKDIDGEVTTLEKFAGNVLLIVNVASKCGLTPQYE
                     QLENIQKAWVDRGFMVLGFPCNQFLEQEPGSDEEIKTYCTTTWGVTFPMFSKIEVNGE
                     GRHPLYQKLIAAAPTAVAPEESGFYARMVSKGRAPLYPDDILWNFEKFLVGRDGKVIQ
                     RFSPDMTPEDPIVMESIKLALAK"
     gene            complement(4535..5515)
                     /gene="btuC"
                     /locus_tag="IT892_002780"
     CDS             complement(4535..5515)
                     /gene="btuC"
                     /locus_tag="IT892_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="HAP3135979.1"
                     /translation="MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWF
                     TPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLI
                     AAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
                     TWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGE
                     ISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLL
                     PGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR"
     gene            complement(5616..5915)
                     /gene="ihfA"
                     /locus_tag="IT892_002781"
     CDS             complement(5616..5915)
                     /gene="ihfA"
                     /locus_tag="IT892_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HAP3135980.1"
                     /translation="MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQV
                     KLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE"
     gene            complement(5920..8307)
                     /gene="pheT"
                     /locus_tag="IT892_002782"
     CDS             complement(5920..8307)
                     /gene="pheT"
                     /locus_tag="IT892_002782"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012905611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAP3135981.1"
                     /translation="MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFHG
                     VVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCGAPNCRQGLRVAVATIGAVLPGD
                     FKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPIGTDIREYLKLDDNTIEI
                     SVTPNRADCLGIIGVARDVAVLNQLPLVQPEIVPVGATIDDTLPITVEAPEACPRYLG
                     RVVKGINVKAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIEGGI
                     VVRMAKEGETLVLLDGTEAKLNADTLVIADHNKALAMGGIFGGEHSGVNDETQNVLLE
                     CAFFSPLSITGRARRHGLHTDASHRYERGVDPALQHKAMERATRLLIDICGGEAGPVI
                     DITNEATLPKRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVTEGKDEWQAVAPS
                     WRFDMEIEEDLVEEVARVYGYNNIPDEPVQASLIMGTHREADLSLKRVKTLLNDKGYQ
                     EVITYSFVDPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNRQQNR
                     VRIFESGLRFVPDTQAPLGIRQDLMLAGVICGNRYEEHWNLAKETVDFYDLKGDLESV
                     LDLTGKLNEVEFRAEANPALHPGQSAAIYLKGERIGFVGVVHPELERKLDLNGRTLVF
                     ELEWNKLADRVVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNL
                     FDVYRGKGVAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLRD"
     gene            complement(8322..9305)
                     /gene="pheS"
                     /locus_tag="IT892_002783"
     CDS             complement(8322..9305)
                     /gene="pheS"
                     /locus_tag="IT892_002783"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAP3135982.1"
                     /translation="MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTT
                     LRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIE
                     NGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
                     DTTRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNI
                     SFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVH
                     PNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK"
     gene            complement(9589..9633)
                     /locus_tag="IT892_002784"
     CDS             complement(9589..9633)
                     /locus_tag="IT892_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl--tRNA ligase operon leader peptide"
                     /protein_id="HAP3135983.1"
                     /translation="MNAAIFRFFFYFST"
     gene            complement(9756..10112)
                     /gene="rplT"
                     /locus_tag="IT892_002785"
     CDS             complement(9756..10112)
                     /gene="rplT"
                     /locus_tag="IT892_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016169860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAP3135984.1"
                     /translation="MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQ
                     YAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFD
                     KVAFTALVEKAKAALA"
     gene            complement(10165..10362)
                     /gene="rpmI"
                     /locus_tag="IT892_002786"
     CDS             complement(10165..10362)
                     /gene="rpmI"
                     /locus_tag="IT892_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAP3135985.1"
                     /translation="MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHL
                     RPKAMVSKGDLGLVIACLPYA"
     gene            complement(10459..11001)
                     /gene="infC"
                     /locus_tag="IT892_002787"
     CDS             complement(10459..11001)
                     /gene="infC"
                     /locus_tag="IT892_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAP3135986.1"
                     /translation="MKGGKRVQTARPNRINGEIRAQEVRLTGLEGEQLGIVSLREALE
                     KAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGT
                     DEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVES
                     FPTKIEGRQMIMVLAPKKKQ"
     gene            complement(11005..12933)
                     /gene="thrS"
                     /locus_tag="IT892_002788"
     CDS             complement(11005..12933)
                     /gene="thrS"
                     /locus_tag="IT892_002788"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010245687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAP3135987.1"
                     /translation="MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGEL
                     VDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGF
                     YYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSIL
                     DENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRI
                     YGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRE
                     LEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNC
                     PGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQ
                     IRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNI
                     PFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPV
                     MIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAG
                     IRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEV
                     IEKLQQEIRSRSLKQLEE"
     gene            13457..15356
                     /locus_tag="IT892_002789"
                     /pseudo
     CDS             13457..15356
                     /locus_tag="IT892_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ShET2/EspL2 family type III secretion system
                     effector toxin"
     gene            15528..15635
                     /locus_tag="IT892_002790"
     CDS             15528..15635
                     /locus_tag="IT892_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135988.1"
                     /translation="MPTKRFDKKHWKMVVVLLAICGAMLLLRWAAMIWG"
     gene            complement(15688..16446)
                     /locus_tag="IT892_002791"
     CDS             complement(15688..16446)
                     /locus_tag="IT892_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiY family protein"
                     /protein_id="HAP3135989.1"
                     /translation="MKLLKTVPAIVMLAGGMFASLNAAADDSVFTVMDDPASAKKPFE
                     GNLNAGYLAQSGNTKSSSLTADTTMTWYGHTTAWSLWGNASNTSSNDERSSEKYAAGG
                     RSRFNLTDYDYLFGQASWLTDRYNGYRERDVLTAGYGRQFLNGPVHSFRFEFGPGVRY
                     DKYTDNASETQPLGYASGAYAWQLTDNAKFTQGVSVFGAEDTTLNSESALNVAINEHF
                     GLKVAYNVTWNSEPPESAPEHTDRRTTLSLGYSM"
     gene            16733..17662
                     /gene="pfkB"
                     /locus_tag="IT892_002792"
     CDS             16733..17662
                     /gene="pfkB"
                     /locus_tag="IT892_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416237.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase II"
                     /protein_id="HAP3135990.1"
                     /translation="MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINV
                     ARAIAHLGGSATAIFPAGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGE
                     QYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQG
                     IRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKA
                     KRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMV
                     RFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR"
     gene            17763..18053
                     /gene="ghoS"
                     /locus_tag="IT892_002793"
     CDS             17763..18053
                     /gene="ghoS"
                     /locus_tag="IT892_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HAP3135991.1"
                     /translation="MASGDLVRYVITVMLHEDTLTEINELNNYLTRDGFLLTMTDDEG
                     NIHELGTNTFGLISTQSEEEIRELVSGLTQSATGKDPEITITTWEEWNSNRK"
     gene            18159..19019
                     /locus_tag="IT892_002794"
     CDS             18159..19019
                     /locus_tag="IT892_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAP3135992.1"
                     /translation="MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFV
                     KCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVGADRDYSFLVMDYLPPRPLDAHS
                     AFILGQQIARLHQWSDQPQFGLDFDNALSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
                     EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDR
                     ECDLAMLPLHTEQPPQIYDGYQSVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIA
                     QQSLDRLLAA"
     gene            complement(19060..19596)
                     /locus_tag="IT892_002795"
     CDS             complement(19060..19596)
                     /locus_tag="IT892_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135993.1"
                     /translation="MTYQQAGRIAVLKRILGWVIFIPALISTLISLLKFMNTRQENKE
                     GINAVMLDFTHVMIDMMQANTPFLNLFWYNSPTPNFNGGVNVMFWVIFILIFVGLALQ
                     DSGARMSRQARFLREGVEDQLILEKAKGEEGLTREQIESRIVVPHHTIFLQFFSLYIL
                     PVICIAAGYVFFSLLGFI"
     gene            19743..20411
                     /gene="hxpB"
                     /locus_tag="IT892_002796"
     CDS             19743..20411
                     /gene="hxpB"
                     /locus_tag="IT892_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpB"
                     /protein_id="HAP3135994.1"
                     /translation="MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRN
                     ELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVERVIARAISLVEETRPLLPGVREAVA
                     LCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK
                     LGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQNDPRFVLADVKLSSLTELTAK
                     DLLG"
     gene            20574..21164
                     /locus_tag="IT892_002797"
     CDS             20574..21164
                     /locus_tag="IT892_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707386.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP3135995.1"
                     /translation="MTAEGHLLFSIACAVFAKNAELTPVLAQGDWWHIVPSAILTCLL
                     PDIDHPKSFLGQRLKWISKPIARAFGHRGFTHSLLAVFALLATFYLKVPEGWFIPADA
                     LQGMVLGYLSHILADMLTPAGVPLLWPCRWRFRLPILVPQKGNQLERFICMALFVWSV
                     WMPHSLPENSAVRWSSQMINTLQIQFHRLIKHQVEY"
     gene            21297..22688
                     /locus_tag="IT892_002798"
     CDS             21297..22688
                     /locus_tag="IT892_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAP3135996.1"
                     /translation="MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFG
                     LALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLG
                     KISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
                     LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLAA
                     IDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFA
                     VHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFA
                     ASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGG
                     ATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKA
                     ILDSEDDAELAHH"
     gene            complement(22692..23495)
                     /locus_tag="IT892_002799"
     CDS             complement(22692..23495)
                     /locus_tag="IT892_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416244.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3135997.1"
                     /translation="MFSTNLIQSNYGDLNIKSLAFDSFKERLQSTMTALTFFISTGQC
                     DCDEIAESNFNYMIAYMSNINYDASKPGAPALSFDTYLQDNVKYRVIINNLYGSEIRI
                     RGINKDFIGMDVTSVFRPEKMTNLISIKNRLVIHYLRTIYYEQNYIHPVGSIFAAIQK
                     NESLLKFPSIISMLNINLLFNPLNLPGMGSGVLEDIMSIPDSSLRKRLGYEVLSFSLQ
                     AHSLSQECIDKLDIFFADDLFKYESVCIAAMEHLKSKATAPIQNGPLPA"
     gene            complement(23784..24047)
                     /gene="cedA"
                     /locus_tag="IT892_002800"
     CDS             complement(23784..24047)
                     /gene="cedA"
                     /locus_tag="IT892_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division activator CedA"
                     /protein_id="HAP3135998.1"
                     /translation="MRLVKPVMKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVW
                     MLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQEGEVTE"
     gene            24230..26491
                     /gene="katE"
                     /locus_tag="IT892_002801"
     CDS             24230..26491
                     /gene="katE"
                     /locus_tag="IT892_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase HPII"
                     /protein_id="HAP3135999.1"
                     /translation="MSQHNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTP
                     PGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGP
                     TLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKIT
                     PVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFV
                     HAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHT
                     FRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEY
                     ELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFH
                     PGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHR
                     MGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHP
                     RLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIEL
                     TDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALK
                     AKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDAN
                     YYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIVEADSADGSFMDELLTLMAAHR
                     VWSRIPKIDKIPA"
BASE COUNT         6826 a         6750 c         6183 g         6803 t
ORIGIN      
        1 tcacgcctga aacggatgcc aatcacaaga ccgcttcccc gcagcctatt cggcgaattt
       61 ccagccagac actgttaggt ccggatggca aactgattat cgatcatgac gggcaagaat
      121 atctgctccg taaaactcag gctggcaagc tgctgttgac caagtagcct ttaactcgag
      181 cagctgactt ccagccgttt accccagtca ggtggacgac tgacatagtc atcatctctg
      241 tcgctgaaag gatttcgcaa cgcctcatgc aggcggtgca attccgtcat atcacccttt
      301 tctgccgctt caatcgcccg ttgcgccaac cagttgcgca ataccagagc ggggttaacg
      361 ctttgcatca gttgctgacg ctcactatcg ctaacctcgt cttgttgcaa acgcccccga
      421 taacgggcaa accagtcatc aaatgccgca cgatcaataa actcatcacg tagcggtgac
      481 gccgcgctgt gctgctcggt cagactcagc atgcggaatg tgcgggtata atcgctgcgc
      541 tctcgcgcca tcagactgaa taattcattc agtagcgcgt tatcctcttt ttgctccgtc
      601 atgaagccca gtttctgccg catccgttct ccataatgcg tcaacaaaac ctgctgatag
      661 ctgtccaggg cctcattcag ggcatctacg gcaacaaatg gcgacaatgt ctgcgccaga
      721 cgctgtaaat tccacaacgc gacggcaggt tgattatcaa agctgtaacg cccttgatga
      781 tccgagtgat tacaaataaa accgggttcg taatcatcaa gaaaaccaaa cggcccgtaa
      841 tcaagcgtca gccccagcag cgacatgttg tcggtattca tcaccccatg agcaaagccg
      901 accgtctgcc attgggcaat taacgacgcg gtacgtgcga caacatcgct aaaccagaga
      961 cggtatttgt cctcatcatc tgcaagatgt gaccagtaat gacgaatagc aaagtcagct
     1021 aactgacgaa ccttttccga ctcgcggcgg tagtaaaaat gttcgaaatg accaaagcgc
     1081 agatgacttg gtgccacacg catcagcatc gcgcctggct ccgccgtttc ccgatacact
     1141 ggcgaatcgc tggtgacgat acttaacgcg cgggtcgtcg gaatgcccag ataatgcatc
     1201 gcctcactgg cgagactttc tcgtatcgtc gaacgtaaaa ccgcccgtcc atcacccatt
     1261 cgcgaataag gcgtcaggcc agcacctttc agatgccagt ccattgtagt gccatcagca
     1321 agcagttgtt cgccgagtaa aatgccgcgc ccatcaccca gttggcccgc ccagacgccg
     1381 aactgatgac cactgtaaac ctgcgccagt ggtgacatac caggcagtag ggcttcgccg
     1441 ccccagacac ctgcgccatt tttaaacagc gacgatggaa tactcagcgt gttagccagt
     1501 tcggtattat gccaaatcag ccgggcatta tttaaaggcg taggggaaag tgctgtatag
     1561 gtttctggca attcatcgcg ccagcgggta acaaaagaca gggtcataga tcctcctgtt
     1621 tgatagtgta gacggttact ctcgtcttaa acaccagcaa acagaagggt tatcgctgaa
     1681 ccaacgtcgt tatctgattt atgggaacgg caggccacag gcatccctgg agagcatgga
     1741 aatcgaaggg ggtaatctgt gccaatattt ctgccgtatc aatgcctccc gcaatgatgc
     1801 aattgcaaca aggggaaatt tgcgcctgga tcgcacgaat aaacggttcg aaggagcggt
     1861 gcgtgatttg ttgctgaata aaacttttat ccagcatgac gcgggtgaaa agaccatcaa
     1921 aaaccgcttt cattgtgcta ttgcctgctc ccaaattacc taacacaagg ggatacactt
     1981 gcgataagga taaaagaccg cgattatctt ttccttcatt gagatgcggg taattctcat
     2041 taatcaacag ttcaataaac ggatatttta atagttcgcc tgcgtaatta tccctctcta
     2101 ataataatgt agccacttgt ggcgttaaat taagccaggc aaagagttta tgttgaataa
     2161 aaaaatgttg gcatgatttt agtaattcca actgctctga aaataattgc caatgttgct
     2221 cctcggtaag ttgcgctata acccgactcg tcgggatacg aaccgtacca tcttcactgg
     2281 agaaatgggt aattaactca acgccgacaa ggacttgctg gttgtctctt atcggcagga
     2341 aatagcaatc agaatgataa agattctcca aaaaaatctt catggtaacc gtccctctcg
     2401 aaggatgttt ttcagtatcc ggctaaaagg gatgaggcca taagacataa caattacaga
     2461 aggagtaact ttcatttgtt ccatgttaac cactttttca ggggtccttt ttttagatta
     2521 tcctgattat aaacgaataa tccatttacg gaatttttgt ctgcaaaata ctactgtatt
     2581 caggagtaaa tggacggcga tgtatcatcg ccgtccattt ttcgacatac tagattcgtc
     2641 tcgcctgcca gaaatttttc tgccaataga cattatcaag tgaggaacgc atcactccct
     2701 tgctggtaga ggcgtggata aattggttgt tggtatcgta aatacctaca tgcaaaccat
     2761 tttgtccgga ccccgttttg aaaaagacca ggtcacctgg cagcaactcg tctttatcaa
     2821 tttgcgtgcc aatagaggct tgttgtttgg tttcacgggg cagctgcaaa tcgaaacgat
     2881 cgcgcatcgt cacaaccaca aatcccgaac agtccacacc gcgccgcgtc atgccaccat
     2941 aacgatacgg cgtgccatgc cagctttgta gctggtcgtt caaaccggca ataacggtaa
     3001 tcgaatcaga aagtctggca tttggcggcg gtgctttatg gtggctacac ccggccagaa
     3061 gcagtgctgt gatcaaaata aggcagaaac gcattccgta cggttcctct gttttttatt
     3121 cttgcattaa tttagtgtcg taattacccg attttcaaga tactaatgaa atcagatggt
     3181 cgaaatcagc attctgtgac cttcgatatc cagacggcga aaattcatcc cataggcctg
     3241 cgccagattt ggcggcgtga gcacctcttc cctgcgtcca ctggccagca tttttccacc
     3301 ttttagcaac cacgcccgat gcgcatgacg caatgtgtgg ttgagatcgt gactgctcat
     3361 cacaatcgcc agtccttgct gacacagcgc gctcagaatt ttgtctaacg cactttgttg
     3421 cgcaacatca agactgttca tcggctcatc aagaagcagc aattggcctg cgggattggc
     3481 ttgtggtgtg atttgcaaca ccaccgcagc aagacgtacg cgttgccatt caccgccgga
     3541 aagttgattg gtgctacgtc cgagtttgtc atcaagagcc agcgcccctg cgacatcatt
     3601 cagtagttcg gtacgcgttt tatcgtgctg atgcagtgtc aggtagtgcc agaccggcat
     3661 tgcaaacggc ggcgtctgct gttgtgaaag ataggcgcga tgcagcgcga gttttgttgc
     3721 ggaccatgct tccagtggtt gccccgcgaa ctgaatgctt cccttaccgc tggtcattcc
     3781 ggccattcgc gccagtaagg tactcttacc cgcgccattc ggccccacca ggtgcaggat
     3841 ctccccagcc cgaacctcgc cagaaagcgg ccccaggcgg gtagattccg caacatcttg
     3901 taactgcatc acaatagaca ttattttgcc aacgccagtt taatgctttc catcacaatg
     3961 ggatcttccg gcgtcatatc cggggaaaaa cgctggatga cttttccgtc cctgccaacc
     4021 aggaattttt caaaattcca taaaatatca tccgggtaca gcggtgcacg gcctttgctg
     4081 accatacggg catagaatcc gctctcttcc ggcgcgactg cggtcggcgc tgcggcaatc
     4141 aatttttgat acagcggatg gcgtccttcg ccattaactt caatcttact gaacatcggg
     4201 aacgtcaccc cccatgtggt ggtacagtaa gttttaatct cttcatcgct gcccggttct
     4261 tgttccagaa actggttgca cgggaatccc agcaccataa aacctcgatc gacccaggct
     4321 ttctgaatat tctccaactg ctcatattgc ggcgttaagc cacactttga ggcgacattg
     4381 acaatcaaca gcacattacc ggcgaacttc tccagcgtgg tcacttcacc gtcgatatct
     4441 ttcactacgg tcgtcagaat ggaatcttgc atcgtttctc ctgggtgtgg tcagtaaaaa
     4501 tcttagcttt taatcataga ccgtcttttt gcggctaacg tcctgctttt aacaataacc
     4561 agataaacac cggcgcacct aacgttgcgg tgaccacgcc aataggcagc tctgcggcag
     4621 ctaatgccag gcgcgctaca atatcggcca gcagcaatgc gctcgcccct gccagcgcgc
     4681 agccgggaag taatacgcga tgatcggtta aaccacacaa ccggagaata tgggggatca
     4741 ccagaccaat aaagccgata gcacccgcca gcgccacact gacgccaacc atccagccgg
     4801 tcgctgccac cagcacattg cgccagaacc acaggggtaa acccagttgc cgcgccgaga
     4861 tctcaccaag tgctaacata ttcatcggcc tggactgaca acagatccac aacaacacgg
     4921 ggatcaatgc cagcatcagc cagctttgcc gccagtctac gccgccaaaa ccgcccatca
     4981 tccagtacat cagctgacgc aaatcaactg aggtggaaaa gtagatagcc cacgtcatta
     5041 gtgcgctaca gataatccct aatgcaacgc cagccagcaa taaccgactg gtcgaaagat
     5101 gacgacgggc gaaacgtaag agtattaaag tgatgataag cgcgccagca atcgcacaca
     5161 gccctagcgc ccagttgggg agttgccctt gcccaagcaa taccgcggcg ataagcccca
     5221 cgcctgcgcc gttagagacg ccaagtagtc caggttctgc cagaggattt tcaaacaacg
     5281 cctgcattac agcgccggat atagccagcg ccgcaccaac cagcaataca gccagcgtac
     5341 gtggcaggcg aatttgccag acgaacagtt cgccacgagg agtaaaccag tcacctggcg
     5401 agatccattg ttcaccggcg caaaggctta agagaagcgc cagcagcatc aaaactgaca
     5461 ggcataataa ccagcgaata ttttgtcgct gttgttggcg ggcaagtgtc agcatggtat
     5521 ccgttctgct gaagtgtcat ggcgttgatt ttacggtgac tcttcgacag tgaaaagaaa
     5581 aaaggccgca gagcggcctt tttagttaga tcagattact cgtctttggg cgaagcgttt
     5641 tcgacccggc tttttaactt ctgcccgggt ctgaaggtca ccacgcgccg tgctgtaatg
     5701 ggaatatcct cgcccgtttt cgggttacgt cccgggcgtt gattcttatc acgcagatcg
     5761 aagttaccaa aaccagagag tttcacctgt tcgccgtttt ccagagcgcg acggatctct
     5821 tcgaaaaaca gttcaaccag ttctttggca tcccgcttgc taagcccaag cttatcaaac
     5881 agatattctg acatttcagc ttttgtaagc gccataggtt caatccctca atgatgcctg
     5941 gaatcgctct tttaatgcct ctacacattt ggcgacggta gcggcaatct cctcttcttc
     6001 gagtgtacgg ctggtatctt gcaggatcag gcttatggcg aggctcttat acccctccgc
     6061 aacaccctta ccgcggtaca cgtcaaataa gtttacgcca actacctgat ttacgccaac
     6121 tttcttacat tcggataaaa tatccgctgc gggaacgttt tctgcgacca ccaccgcgat
     6181 gtcacgacgg ttcgccggga agcgagaaat ctcgcgcgcc tgaggcacca cgcggtctgc
     6241 gagcttgttc cactccagtt cgaacaccag agtgcgaccg ttaagatcca gtttacgttc
     6301 cagttcagga tgaacaaccc caacaaaacc aatacgttca cctttcagat aaatcgctgc
     6361 ggattgcccc ggatgcagtg ccggattcgc ttctgcacgg aactcaacct cattcagttt
     6421 accggtcagg tcgagaacgg attcaagatc gcctttcaaa tcatagaaat caacggtctc
     6481 ttttgccagg ttccagtgct cttcgtaacg gttaccgcaa atcacaccgg ctaacatcag
     6541 atcctgacga atgcccaacg gtgcctgagt atctggtacg aaacgcagac cgctttcgaa
     6601 aatgcgcaca cggttctgct gacggttctg gttgtacacc acggttgcca gcaggccagt
     6661 ccacagagaa agacgcattg ctgacatttc aacagagatc gggcttggca gcagtaaggc
     6721 ttcaacgcct ggatggatca tctgctgcac tttcggatca acgaagctgt aggtgatcac
     6781 ttcctgatag cctttgtcgt tgagcagcgt tttcacgcgc ttgagcgaca ggtcagcttc
     6841 acggtgagta cccataatca ggcttgcctg taccggctca tccgggatgt tgttgtagcc
     6901 gtaaacacgc gcgacttctt caaccagatc ttcttcaatc tccatatcga aacgccagct
     6961 cggcgcaact gcctgccatt cgtctttgcc ttcggtcact tcgcagccga gacgacgcag
     7021 aatgtcagtt acctgctcat ccgcaatatg atggccgatc aggcgatcca gtttgctacg
     7081 acgtagagtg atggttgcac gcttcggcag cgttgcttcg ttggtgatat caattaccgg
     7141 gccagcctca ccaccgcaga tgtcgatcag cagacgggtc gcacgttcca tcgctttgtg
     7201 ctgcagtgcc ggatcaacgc cacgctcata acggtgagac gcatcggtat gcaggccatg
     7261 acgacgagca cgaccggtga tagacagcgg gctaaagaac gcgcattcca gcagcacgtt
     7321 ttgtgtttcg tcattcacgc cagagtgttc gccaccgaag atgccgccca tcgccagcgc
     7381 cttgttgtgg tcggcgatga ccagagtgtc agcattcagc ttcgcttcag taccgtcgag
     7441 cagcaccagc gtttcgccct ctttcgccat ccgcaccaca atgccgcctt caatgcgatc
     7501 tttatcgaaa gcgtgcatcg gctggcccag ttcgagcagc acatagttgg tgacgtcaac
     7561 aactgcatcg atagaacgga tcccgcaacg acgcagtttt tctttcatcc acagcggagt
     7621 tggcgcttta acgttaatgc cttttaccac acggccaaga taacgcgggc aggcttccgg
     7681 cgcttcgact gtaatcggca gcgtgtcgtc gatggtcgca ccaaccggaa cgatttccgg
     7741 ttgaaccagc ggcagctggt tcagcacggc aacgtcacgc gcaacaccaa tgatgcctaa
     7801 gcagtcggca cggtttggcg tcacgctgat ttcgatggtg ttgtcatcaa gtttcaggta
     7861 ttcacggata tcggtgccaa tcggcgcatc cgcaggcagt tcgataatgc cgctgtgatc
     7921 gtcagaaatg cccagttcag agaaggagca cagcatccct tcagacggtt cgccacgcag
     7981 tttcgccgct ttaattttga aatcacccgg cagaacagca ccaatggtcg ctaccgctac
     8041 acgcaagccc tgacggcagt ttggcgcacc gcagacgatg tccagcaggc gatcgccgcc
     8101 gacattcact tttgtcacac gcagtttgtc agcgttcgga tgctgcgcac actcaaccac
     8161 ttcaccaacg accacgccgt ggaagctgcc ggcaaccggt tctacaccgt caacttccag
     8221 gcccgccata gtgatttgat ttgccagcgc atcgctatca atcgccgggt tcacccattc
     8281 gcgtaaccac agttcactga atttcataat ctattcctgc cttatttaaa ctgtttgagg
     8341 aaacgcagat cgttttcgaa gaatgaacgc aggtcggtga cgccgtaacg caacatagtc
     8401 agacgctcca tccccatccc gaaggcgaaa ccagagtaaa cttccgggtc gatgccaacg
     8461 ttacgcaaca cgttcggatg caccatcccg cagcccagca cttccagcca tttaccgttt
     8521 ttacccatga cgtccacttc tgcagaaggt tcggtaaacg ggaagtagga aggacggaag
     8581 cgaatctgca aatcttcctc aaagaagtta cgcaggaagt cgtgcagcgt gcctttcagg
     8641 ttggtaaagc tgatgttggt atcaacaatc agaccttcca tctgatggaa catcggcgtg
     8701 tgagtctggt cgtagtcgtt acgataaaca cggccaggcg cgatgatacg aatcggtggc
     8761 tgctgggctt tcatggtgcg gatctgtacg ccagaggtct gggtacgcag caggcgggta
     8821 gtgtcaaacc agaaagtgtc gtggtcagcg cgcgccgggt ggtgaccagg aatgttcaga
     8881 gcatcgaagt tatgataatc gtcttcgatt tccggcccgg ttgccacggt aaagccaagc
     8941 tcaccgaaga aactttcgat acggtcgatg gtacgggtaa ccggatgcag accgccgttt
     9001 tcaatgcgac gacctggcag agagacatca atcgtttccg ccgccagacg cgcattcagt
     9061 gcagcgcttt ccagttccgc tttacgcgca ttcagcgcct gctgaacctg ctctttcgct
     9121 tcgttgataa ccgcaccagc tgccggacgc tcttctggcg gcagctcacg cagggtcgtc
     9181 atctgaaggg ttaagtgccc ttttttaccc aaatattcga cgcgcacatt atctaacgcg
     9241 gcaacatctg acgcctggct aatggccgcc ttcgcactgg caaccagttc tgcgagatgt
     9301 gacatggttt tcctcattgt gtcagtggtg acactggttc gttggactta gagcctatcc
     9361 catcaggcta ttttacttgc cattttggtc ccgggctgtg ctcgaaattc tcacgtactt
     9421 aaatacgctc cggtttctcc gcgctggccg tgtccagtct ggctgcgaca attacacctg
     9481 atgagacagg ctttttattt ttcaaaacgc gcatacaaaa aaagcctcca ctgggaggct
     9541 ttcaggcgct gttttccgtt tctcttctca cgcgctagcc tcctggattc aggtgctaaa
     9601 gtaaaaaaag aagcggaaaa tagcagcatt cattgcttgc gttacctttt ggtactcttc
     9661 aaaagacctt tattgaaaag gctacggcga taaaagtcaa tgttttgatg gcgttgaaac
     9721 gaaaagaggg agactagctc cctctttcaa ctggcttatg ccagagctgc tttcgctttt
     9781 tcaaccagag cggtgaacgc tactttgtcg aatactgcga tatcagccag gatcttacgg
     9841 tcgatttcaa cagaggcttt tttcaggcca ttgatgaatt tgctgtaaga aataccgttc
     9901 tgacgtgctg ctgcgttgat acgcgcaatc cacagttgac ggaactgacg cttacgttga
     9961 cgacggtcac ggtaagcata ctgaccagct ttgataacag cctggaaggc aacgcggtat
    10021 acgcgagaac gcgcaccgta gtagccttta gcttgtttca aaattttctt gtgacgtgca
    10081 cgtgcaataa caccacgttt tacgcgagcc atatgtgctc tcctgtatct atattctaat
    10141 taaaaagtta aaaacgttaa cggcttatgc gtacggcagg catgcgatta ccaggcccag
    10201 atcgcctttg gaaaccatgg ctttcggacg caggtgacgt ttacgtttgg tcgctttttt
    10261 ggtcagaatg tgacgcaggt tagcgtgctt gtgcttaaaa ccacctttac cggttttttt
    10321 gaagcgctta gcagcaccgc gtacggtctt aatttttggc attttaataa cttccacttc
    10381 gcattgttaa taaacgaaac aaaggcgaac aaagcctgtg aagcccgaag gctccacaga
    10441 cagtgctact tgaaggcctt actgtttctt cttaggagcg agcaccatga tcatctggcg
    10501 gccttcgatc ttcgttggga aggattcgac cactgccagt tcttgcaaat cgtctttcac
    10561 gcgattaagc acttccatac cgatttgctg gtgcgccatc tcacgaccgc ggaaacgcag
    10621 cgtgattttg gctttatcac cctcttcgag aaagcgaatc aggctgcgga gttttacctg
    10681 atagtcgcct tcatctgtac caggacggaa tttaatttcc ttaacctgga taactttttg
    10741 ctttttcttc tgttccttag aagacttgct cttttcatag aggaatttgc cgtaatccat
    10801 tatacgacaa accggcggct cggcgttagg gctgatctcg actaagtcta ctccggcttc
    10861 ttctgctttc tccagagctt ctctcagact cacaatacca agctgctcgc cttccagacc
    10921 tgttaagcga acttcctggg cgcgaatttc gccattgata cggttagggc gcgccgtttg
    10981 aactcgtttt ccgcctttaa taccttattc ctccaattgt ttaagactgc ggctgcgaat
    11041 ctcttgttgc agcttctcga tcacttcatt tacgtccatg cttcccaggt ctttaccacg
    11101 gcgggtgcga acggcaactt tgcctgattc cacctcttta tcaccacaga ccagcatata
    11161 tgggacgcga cgcaaagtgt gctcgcggat tttaaagcca atcttctcat ttctcaagtc
    11221 tgctttaaca cgaatgcccg catttgatag tttttgcgtc aattcgttaa cgtattcaga
    11281 ctgtgaatcg gtaatattca tgataacaac ctgaaccggc gcaagccagg tcgggaagaa
    11341 accagcgaac tcttcggtca ggataccgat gaaacgttcc atcgacccca gaattgcgcg
    11401 gtgaatcatt accggtactt tacgttcatt gtcttcgcct acataagaag cgctcagacg
    11461 agacggcaaa gagaagtcca gctgtactgt accgcactgc catgcacgat cgaggcagtc
    11521 atacagggta aattcaattt tcggaccgta gaaagcgcct tcacccagtt gatattcaaa
    11581 cgggatgttg ttttcttcca gcgcaaccgc caggtccgcc tcagcacgat cccacatttc
    11641 gtcgctgcca atacgttttt caggacgagt ggagagtttg acgacgatct tctcgaagcc
    11701 aaaagtgctg tacatatcat agactaaacg gatacatccg ttaacttcat cgcgaatttg
    11761 ttcttcagta cagaagatat gcgcgtcatc ctgggtaaat ccacgcacgc gcatcaggcc
    11821 atgcagcgaa cctgacggct cgttacggtg gcagctacca aactcggcca tacgcagcgg
    11881 cagatcgcga taagacttca gcccctggtt gaaaatttgt acgtgacccg ggcagttcat
    11941 cggcttaatg cagtattcac ggttctcaga agatgtggtg aacattgcat ctttgtagtt
    12001 gtcccagtga ccggtttttt cccacaggac acggtccatc atgaacggac ctttaacttc
    12061 ctgatactgg tactctttca gtttagaacg aacaaacact tccagttcac ggaagatggt
    12121 ccagccgtcg ttgtgccaga ataccatacc cggcgcttct tcctgcatat ggtacaggtc
    12181 gagctgttta ccgattttac ggtggtcgcg tttcgcggct tcttccaggc gctgcaggta
    12241 agcgttaagt gcttttttgt ctgcccacgc cgtaccgtaa atacgttgca acattttgtt
    12301 gttgctgtcg ccacgccagt aagcccctgc cgttttcatt agtttgaaat gatggcagaa
    12361 acgcatgttc ggtacgtgcg gaccgcggca catatcgaca tattcttcat ggaagtacag
    12421 acctggcttg tcatcatggg cgatgttttc gtcaagaatg gagactttgt agctctcccc
    12481 acggttggcg aaagtttcac gcgcttcgtg ccagctgact ttcttcttaa tgacgtcgta
    12541 gtttttctca gcaagctcat gcatccgctt ctcgagtgct tcgacatctt cctgggttaa
    12601 cgtgcggtca agatcaacgt cgtaataaaa accgttgtca ataaccgggc cgattgccat
    12661 tttggtatgc ggccaaagtt gtttaatcgc gtgccctaac aggtgcgcac aggagtgacg
    12721 aatgatctcc agaccttctt cgtctttggc ggtaatgatc gacagttgtg cgtcgttttc
    12781 aatcagatcg caagcatcaa ccagttcgcc attaacgcgc cctgcgatac aggctttcgc
    12841 cagacctgga ccaatgtcca gcgcaacatc catggggctt acagcgtgat cgtaatggcg
    12901 ttggctgcca tcaggaagag ttataacagg cattttatat ccttatttgc agtggtgacc
    12961 cacacgaaag atcacataca aagaaaaatt tgtttattaa cagttcattg cgaaaccatc
    13021 tagccaacaa atgctaaatt ggttcgcaat caggtacaca aatgaaagac attaacctct
    13081 caccttccac ccggttgagc gatgttaaca ctaaaaaaag ggagattgta cctttccgtt
    13141 tcacattgat tcgattcgca attcgtttgt agtgagtaca ccagcaaaac gcttaaagaa
    13201 caactgataa catcacggtg cgtctgaaag gtttactgcg agcggattta cagcagcata
    13261 aactgaatcc agcaaagttc gttgcgtgat ttggcggtag tattttaaac gctcatgaga
    13321 ttaatgacga agtggtcata tcacaatgat aaaagtgaca caattcttat aacaattttt
    13381 cgtgcacatt tcgttctggc gataataatt aatcatcatc ctcaaaacct ccagatatat
    13441 ataaggcgaa cagattatga gtcaaaacga tatcattatc agaactcatt ataagtctcc
    13501 tcatagattg cacatcgata gcgacatacc aacaccttca tcagagccta ttaatcaatt
    13561 tgcgcgccag ctcatcaccc tacttgatac ctctgactta agttcgatgc tgtcatactg
    13621 tgttactcag gaatttaccg caaactgtcg aaaaatatca caaaattgtt attccactgc
    13681 cctttttacc attaactttg ccacttcacc catccataca gaaaatatac tcattacatt
    13741 acactataaa aaagaaatca tttccttatt actggaaacc acgcctatta aagctaacca
    13801 tttgcgaagc atactggatt atattgaaca ggaacagtta actgctgaag atcgtaacca
    13861 ttgtatgaaa ctgtctaaaa aaatccatag agaaaaaaac tatacaccca acagtaaatc
    13921 tcaatggtag tgcatgtttt ttgcaatctc cttctgacgc tattttttgt cgccatctgt
    13981 cattgcaata cgcccttgat tcattgagaa atggaaaagg caaagtcaac ctgattaaac
    14041 attactcctc cgttgaatcc atacagcagc atgtcccctt agtccgggac gcggagttca
    14101 gagcattact tcgccatcct cctgcaggga gtcgcgttat cgcgagtaag gattttggct
    14161 tcgctttaga tattttcttt tgtcgaatga tggcaaacaa tgtcagtcat atgtccgcga
    14221 ttttatatat agacaatcat actttgtcag taaggctacg aataaagcag tcagtgtatg
    14281 gacaattaaa ttatgttgtg tccgtttacg acccgaacga taccaacgtt gccgtcagag
    14341 acacccacag gacagcacgg ggctttcttt cgcttgataa gttcatcagt tcaggtcccg
    14401 atgctcagac ctgggctgat agatatgttc gcaactgtgc aattgctatt ctgcccctat
    14461 tacctgtggg agttccaggg gctattttcg cgggtattgc atcacgaatg ccatttgccc
    14521 ctatacatcc atcggcaatg ttgttaataa tggctacagg ccagactcaa cagcttatta
    14581 cattattcaa acagttgccc atactccctg aaaaagaaat cattgaaata ataactgcgc
    14641 agaatagcgt tggtacacct gctttatttt tggctatgat gaacggacat actgacaacg
    14701 tgaaaatatt tatgcaagaa attcagtcac tggtagataa tcacatcatt catgaagata
    14761 atctggttaa attactgcaa actaaaagtg ctaacgaaac acctggactt tatatctcca
    14821 tgttgtatgg attcgatgaa ataatcgata tctttctgaa tgcattaacc actccaatag
    14881 cacaagagct tttaaacaaa aaactggtga tgagtatttt agccatgaaa atacatgatg
    14941 gtgagccagg attatacgcc gcaatggaaa ataatcaccc tttgtgtgtc acacggttcc
    15001 tctctaaaat taatggcatc gcctttaaat acaagttgag caaagctaac atcatggatt
    15061 tattaaaagg agctacagca cagggaaccc ctgcattata catcgccatg agcaagggta
    15121 atgaagacgt cgtgttatct tatatatcga cgctgggtgc ttttgcaaaa aaacattctt
    15181 ttagtcaaca tcagttattt acactattgg ccgctaaaaa tcatgacaac atgtcagctg
    15241 ttcatatagc cattcatcat aagcattata aaactgtaga aacatattat gctgctatta
    15301 atgcaatcag ccaaagcctg agttttagtg ctgatgaaat aaagacgtat ttataaccag
    15361 ctatttacga tatatatcga tacataattt tatttttttc ataaaacgca gaaacagtga
    15421 ccatgtgcac aacgccaccc gacggctgta ataacaaaaa atcccttgat gcctgtccct
    15481 tttgttacac tccgttatca cgcacaagag atatgcagga cactggtatg ccgactaaac
    15541 gctttgataa aaaacactgg aagatggtgg tggtgctact ggcaatctgt ggcgctatgt
    15601 tgttgctacg ttgggcagca atgatttggg gctgagcagt gacaaacgaa gacagccaga
    15661 ccgcataaca cggtccggca gataatttta catgctgtag cccagcgata aggttgtccg
    15721 acggtcggta tgttccggtg cagactctgg aggttcagag ttccatgtga cgttgtaagc
    15781 caccttcagt ccaaaatgtt cattaatagc aacatttaat gcgctttcgg agttcagcgt
    15841 tgtgtcttcc gcgccaaaga ccgaaacacc ctgcgtaaat ttagcgttgt cagtcaactg
    15901 ccatgcataa gccccggagg catagcccag cggctgggtt tcactggcat tgtcggtata
    15961 tttgtcgtaa cgcacacctg gaccgaattc aaagcggaaa ctgtgtaccg ggccattcaa
    16021 aaactgacga ccataacccg cggtcaacac atcgcgctct cgatagccgt tataacggtc
    16081 tgtcagccag cttgcctgac caaataaata gtcataatca gttaaattaa aacggctacg
    16141 cccgcccgcc gcatattttt ctgaagaacg ctcatcatta gaagaagtat tactggcgtt
    16201 cccccacagc gaccaggcag tggtgtgtcc ataccaggtc atggtggtgt cagccgtaag
    16261 tgaggagctt ttcgtattgc ctgattgtgc aagatatcct gcgttcagat taccttcgaa
    16321 aggtttttta gcgctggcag gatcatccat gacagtaaaa acggaatcat cggcagctgc
    16381 attcagtgac gcaaacatgc cccccgccaa cataacgatg gcaggaactg tcttcaaaag
    16441 cttcatttat caagagtccg tacaacaaaa aaagagacca tcgcggtccc ggaaactttc
    16501 ttaaggatca aagattagcg tccctggaaa ggtaacgaat tataaaaagg cgcgaataac
    16561 ttagcaatgt attcttattt cattttttga ataagcatgt ggcgaaaaca gatttttatt
    16621 tatatatatt tatctgcaaa attttaaata aagctccaat aaatcatatt gttaatttct
    16681 tcactttccg ctgattcggt gccagactga aatcagccta taggaggaaa tgatggtacg
    16741 tatctatacg ttgacacttg cgccctctct cgatagcgca acaattaccc cgcaaattta
    16801 tcccgaagga aaactgcgct gtaccgcacc ggtgttcgaa cccgggggcg gcggcatcaa
    16861 cgtcgcccgc gccattgccc atcttggagg cagtgccaca gcgatcttcc cggcgggtgg
    16921 cgcgaccggc gaacacctgg tttcactgtt ggcggatgaa aatgtccccg tcgctactgt
    16981 agaagccaaa gactggaccc ggcagaattt acacgtacat gtggaagcaa gcggtgagca
    17041 gtatcgtttt gttatgccag gcgcggcatt aaatgaagat gagtttcgcc agcttgaaga
    17101 gcaagttctg gaaattgaat ccggggccat cctggtcata agcggaagcc tgccgccagg
    17161 tgtgaagctg gaaaaattaa cccaactgat ttccgctgcg caaaaacaag ggatccgctg
    17221 catcgtcgac agttctggcg aagcgttaag tgcagcactg gcaattggta acatcgagtt
    17281 ggttaagcct aaccaaaaag aactcagtgc gctggtgaat cgcgaactca cccagccgga
    17341 cgatgtccgc aaagccgcgc aggaaatcgt taatagcggc aaggccaaac gggttgtcgt
    17401 ttccctgggt ccacaaggag cgctgggtgt tgatagtgaa aactgtattc aggtggtgcc
    17461 accaccggtg aaaagccaga gtaccgttgg cgctggtgac agcatggtcg gcgcgatgac
    17521 actgaaactg gcagaaaatg cctctcttga agagatggtt cgttttggcg tagctgcggg
    17581 gagtgcagcc acactcaatc agggaacacg tctgtgctcc catgacgata cgcaaaaaat
    17641 ttacgcttac ctttcccgct aacaaaaaca ttcccccagc attgggggaa tcatcaccaa
    17701 cctgtcggca acgcgtttct ccgactatgc tcaaaagtca tgtgataaca aaggggtgaa
    17761 ctatggccag tggcgatctt gtccgttatg tcataaccgt catgttgcat gaggatacat
    17821 tgactgaaat taacgagttg aataattacc tgactcgcga cggttttttg ctcactatga
    17881 cggatgatga gggaaatatc catgagctgg gaactaacac ttttggactt atcagtaccc
    17941 aaagtgaaga agaaattaga gaactggttt cggggcttac ccaaagtgca accggcaaag
    18001 atcctgaaat caccatcacg acctgggagg aatggaatag caacagaaaa taaatggttt
    18061 ttgggcaata atcagtctgt ggtgtgcgtt agctcgtgtt tttacaccgc attcttgcgc
    18121 taaccttatg atctggcaga caacatggga gagacatcat gtggcaggca atcagtcgtc
    18181 ttttgagcga gcagttaggt gaaggcgaaa tcgaactgcg taatgaactg cctggcggag
    18241 aagtccatgc cgcatggcat ttgcgctatg caggacatga ttttttcgtc aaatgtgatg
    18301 aaagggaact gcttcccggt tttaccgccg aagccgacca actggagtta ctgtcgcgta
    18361 gtaaaaccgt caccgtgcct aaggtttggg cagttggcgc tgaccgtgac tacagttttc
    18421 tggtgatgga ttatctccca cctcgtccgc tggatgcgca tagcgcattt attcttggtc
    18481 agcaaattgc gcgtttacat caatggagcg accaaccaca atttggcctt gatttcgata
    18541 acgcgctctc cacaactcca cagcccaaca cctggcaacg tcgctggtca acgttttttg
    18601 ctgaacaacg gattggctgg cagttggaac tggctgcaga aaaagggatc gctttcggca
    18661 atatcgacgc catcgtcgag catattcagc agcgtctggc ctcacatcaa ccgcagcctt
    18721 ctctgttgca cggcgattta tggtccggca actgtgcact gggtccggat ggcccgtaca
    18781 ttttcgaccc ggcctgctac tggggtgacc gagagtgcga cctggcgatg ttaccgctgc
    18841 atactgaaca gccgccacaa atctatgacg gctatcagtc agtatccccg ctacctgccg
    18901 atttccttga acgtcaaccg gtttaccaac tctacacgct gttaaatcgt gcaaggttat
    18961 ttggcggtca gcatttggtt attgctcagc agtcattgga tagattatta gcagcatgat
    19021 atgggttgag gataatggcc gctccgtgcg gccttttgat taaataaacc caagcagaga
    19081 aaagaacaca taacctgcag caatacaaat aaccggcagg atatacagtg agaaaaactg
    19141 caggaaaata gtatggtgcg gaacaacaat acgggactca atttgttcac gcgttagccc
    19201 ctcttcccct ttggcttttt ccagaatgag ttgatcttca acaccttccc gcaagaagcg
    19261 cgcctggcga ctcatccggg caccggaatc ctgcaacgcc agtccgacaa aaatcaggat
    19321 gaaaatcacc cagaacataa cgttcacgcc accattaaaa ttgggcgtcg gggagttata
    19381 ccagaataga ttcaaaaaag gcgtattcgc ctgcatcata tcgatcatga catgagtaaa
    19441 gtcgagcatg accgcattaa tgccttcctt gttttcctgc cgggtattca taaatttcag
    19501 caaagaaatc aatgtagaga tcaatgcagg tataaaaatc acccaaccca aaatcctttt
    19561 caaaacagca atgcgtccag cttgttgata cgtcatgagt tctccttgat taagacgcgt
    19621 cgtttcactt agtttacctg tagatatctg ttttcgccca ttctttaaag gcgatatgat
    19681 aggcgcttaa tcataagcac ggcttaatac cttacacata atgctctaaa ggagaggttg
    19741 taatgtcaac cccgcgtcag attcttgctg caatttttga tatggatgga ttacttatcg
    19801 actcagaacc tttatgggat cgagccgaac tggatgtgat ggcaagcctg ggggtggata
    19861 tctcccgtcg taacgagctg ccggacacct taggtttacg catcgatatg gtggtcgatc
    19921 tttggtacgc ccggcaaccg tggaatgggc caagccgtca ggaagtagta gaacgggtta
    19981 ttgcccgtgc catttcactg gttgaagaga cacgtccatt attaccaggc gtgcgcgaag
    20041 ccgttgcgtt atgcaaagaa caaggtttat tggtgggact ggcctccgcg tcaccactac
    20101 atatgctgga aaaagtgttg accatgtttg acttacgcga cagtttcgat gccctcgcct
    20161 cggccgaaaa actgccttac agcaagccgc atccgcaagt atatctcgac tgcgcagcaa
    20221 aactgggcgt tgaccctctg acctgcgtag cgctggaaga ttcggtaaat ggcatgatcg
    20281 cctctaaagc agcccgcatg cgctccatcg tcgttcctgc gccagaagcg caaaatgatc
    20341 cacgttttgt attagcagac gtcaaactct catcgctgac agaactcacc gcaaaagacc
    20401 ttctcggtta atgaccaggg gcagtgatct cgctgcccct ggttctttat ctgaaattgc
    20461 attcaactga cggattaatc gtcaatttaa gagaaagagt tacaccgtca ccacttccgt
    20521 gcactgtata aaaatcctat actgtacgta tcgacagttt agtgagtttt atcatgacgg
    20581 cggaaggtca ccttctcttt tctattgctt gtgcggtatt tgccaaaaat gccgagctga
    20641 cgcccgtgct ggcacagggt gactggtggc atattgtccc ttccgcaatc ctgacgtgtt
    20701 tgttaccgga catcgatcac ccaaagtcgt ttcttgggca gcgattaaaa tggatatcaa
    20761 aaccgatcgc ccgcgctttt gggcatcgtg gttttaccca cagtctgctg gcggtatttg
    20821 cgctgctggc aaccttttac cttaaggttc cggaaggctg gttcattccg gctgatgcgc
    20881 tacaaggaat ggtgctgggt tatttgagcc acatacttgc cgatatgctg acacccgccg
    20941 gtgttcccct gctctggcca tgccgctggc gtttccgctt gcctatcctg gttccccaaa
    21001 agggcaacca actggaacgt tttatctgca tggcattatt tgtctggtcg gtatggatgc
    21061 cccattcatt acccgagaac agcgctgttc gttggtcatc gcaaatgatc aataccttgc
    21121 agatccagtt tcatcggctt attaagcatc aggttgaata ctaaaaaggc aaaaatcacc
    21181 tttctggaat aagcaattcc atttgaatat aagagccagc tcacagttct gttaatcttg
    21241 cgccaacact atgactgcta cgcagtgata gaaataataa gatcaggaga acggggatga
    21301 actttccatt aattgcgaac atcgtggtgt tcgttgtact gctgtttgcg ctggctcaga
    21361 cccgccataa acagtggagt ctggcgaaaa aagtgctggt gggtctggtg atgggtgtgg
    21421 tttttggcct tgccctgcat accatttatg gttctgacag ccaggtactt aaagattctg
    21481 tacagtggtt taacatcgtt ggtaacggct atgttcaact gctgcaaatg atcgttatgc
    21541 cgttagtctt cgcctctatt ctgagcgcgg ttgcccgtct gcataacgca tctcagttag
    21601 gcaaaatcag ttttctgacc atcggtacgc ttttgtttac cacgctgatt gcggcgctgg
    21661 tcggtgtgct ggtcaccaac ctgtttggtt tgacggctga aggtctggtt cagggtggtg
    21721 cagaaactgc acgtctgaac gccattgaaa gtaactatgt tggtaaagtc tctgatctga
    21781 gcgttccgca gctggtcttg tcctttatcc cgaaaaaccc gtttgccgat cttaccggag
    21841 ccaatccgac gtcaattatc agcgtggtaa tttttgccgc attcctcggc gtagctgcat
    21901 tgaaactgct gaaggatgat gcgccgaaag gtgaacgcgt cttagccgct atcgataccc
    21961 tacaaagctg ggtgatgaaa ctggttcgcc tggtcatgca gttgacccct tacggcgttc
    22021 tggctctaat gaccaaagtg gttgcaggtt ctaacttgca agacatcatc aaactgggaa
    22081 gtttcgttgt cgcgtcctac ctcggtctgc tgattatgtt tgcagtgcat ggcattctgc
    22141 tgggcattaa tggcgtgagt ccgctgaagt acttccgtaa ggtatggcct gtgctgacgt
    22201 ttgcctttac cagccgttcc agtgctgcgt ctatcccact gaatgtggaa gcacaaacgc
    22261 gtcgtctggg cgttcctgaa tccatcgcca gtttcgccgc ctctttcggt gcaaccattg
    22321 gtcagaacgg ctgcgccggt ttgtatccgg caatgctggc ggtgatggtt gcgcctacgg
    22381 ttggcattaa cccgctggac ccgatgtgga ttgcgacgct ggtcggtatt gttaccgtta
    22441 gttccgcagg cgttgccggt gtcggtggtg gtgcaacttt cgccgcactg attgtactgc
    22501 ctgcgatggg cctgccagta accctggtgg cgctgttaat ctccgttgaa ccgcttatcg
    22561 acatgggccg tacggcgtta aacgttagtg gctcgatgac agctggcacg ctgaccagcc
    22621 agtggctgaa gcaaaccgat aaagccattc tggatagcga agacgacgcc gaactggcac
    22681 accattaatt cttatgctgg caacggtccg ttttgtatag gggccgttgc cttacttttt
    22741 aaatgttcca tcgcggcgat gcatactgac tcatatttaa acagatcgtc agcgaaaaaa
    22801 atgtccaact tatcaataca ttcctggctc aatgaatgtg cctgtagcga gaagcttaaa
    22861 acctcatacc cgagacgttt tctaagtgaa ctatctggaa tactcataat atcttcaagc
    22921 acaccacttc ccattcccgg aagatttagt ggattaaaaa gaagattgat attaagcatt
    22981 gatattatcg aaggaaactt taggagactc tcattttttt gaatcgcagc aaaaatgctc
    23041 ccgacaggat gtatataatt ttgttcatag tatatagtcc ttaaatagtg aataaccaac
    23101 ctgtttttta tactgatcaa attggtcatt ttttctgggc gaaatacaga agtgacatcc
    23161 attccaataa aatctttatt tatacctctt atccgaattt cactaccata aagattatta
    23221 attattactc tatatttaac attgtcctgc agatatgtat caaaactaag tgctggcgct
    23281 cctggctttg aggcatcata gttaatgtta gacatatagg caatcatata attaaagttt
    23341 gattctgcta tttcatcgca gtcacattga cccgttgata taaagaaagt gagtgctgtc
    23401 atagtagact gcagcctttc tttaaaagag tcgaaagcca ggcttttaat atttaaatca
    23461 ccataattac tctgtattaa gtttgtagaa aacatctccc gcctcatatt gttaacaaaa
    23521 ttattatctc atttaaatct aagtcattta caatataagt ttaagagcga cgccacagga
    23581 tgaactatca aaaatagctc atcatgatta gcaaaactta accattttaa aataaataaa
    23641 caattaaaga aaaaagatca cttatttata gcaatagatc gtcaaaggca gctttttgtt
    23701 acaggtggtt tgaatgaatg tagcaacgaa atacagaatt tcaggtcatg taactcccgg
    23761 caaaaccggg aggtatgtaa tccttactca gtcacttccc cttcctggcg gatctgattt
    23821 gcccaacgtt gggcagattc aggcacagta aacgccggtg agcgcagaaa tgactctccc
    23881 atcagtacaa acgcaacata tttgccacgc agcatccaga catcacgaaa cgaatccatc
    23941 tttatcgcat gttctggcgg cgcgggttcc gtgcgtggga catagctaat aatctggcgg
    24001 ttttgctggc ggagcggttt cttcattact ggcttcacta aacgcatatt aaaaatcaga
    24061 aaaactgtag tttagccgat ttagcccctg tacgtcccgc tttgcgtgta tttcataaca
    24121 ccgtttccag aatagtctcc gaagcgggat ctggctggtg gtctatagtt agagagtttt
    24181 ttgaccaaaa cagcggccct ttcagtaata aattaaggag acgagttcaa tgtcgcaaca
    24241 taacgaaaag aacccacatc agcaccagtc accactacac gattccagcg aagcgaaacc
    24301 ggggatggac tcactggcac ctgaggacgg ctctcatcgt ccagcggctg aaccaacacc
    24361 gccaggtgca caacctaccg ccccagggag cctgaaagcc cctgatacgc gtaacgaaaa
    24421 acttaattct ctggaagacg tacgcaaagg cagtgaaaat tatgcgctga ccactaatca
    24481 gggcgtgcgc atcgccgacg atcaaaactc actgcgtgcc ggtagccgtg gtccaacgct
    24541 gctggaagat tttattctgc gcgagaaaat cacccacttt gaccatgagc gcattccgga
    24601 acgtattgtt catgcacgcg gatcagccgc tcacggttat ttccagccat ataaaagctt
    24661 aagcgatatt accaaagcgg atttcctctc agatccgaac aaaatcaccc cagtatttgt
    24721 acgtttctct accgttcagg gtggtgctgg ctctgctgat accgtgcgtg atatccgtgg
    24781 ctttgccacc aagttctata ccgaagaggg tatttttgac ctcgttggca ataacacgcc
    24841 aatcttcttt atccaggatg cgcataaatt ccccgatttt gttcatgcgg taaaaccaga
    24901 accgcactgg gcaattccac aagggcaaag tgcccacgat actttctggg attatgtttc
    24961 tctgcaacct gaaactctgc acaacgtgat gtgggcgatg tcggatcgcg gcatcccccg
    25021 cagttaccgc accatggaag gcttcggtat tcacaccttc cgcctgatta atgccgaagg
    25081 gaaggcaacg tttgtacgtt tccactggaa accactggca ggtaaagcct cactcgtttg
    25141 ggatgaagca caaaaactca ccggacgtga cccggacttc caccgccgcg agttgtggga
    25201 agccattgaa gcaggcgatt ttccggaata cgaactgggc ttccagttga ttcctgaaga
    25261 agatgaattc aagttcgact tcgatcttct cgatccaacc aaacttatcc cggaagaact
    25321 ggtgcccgtt cagcgtgtcg gcaaaatggt gctcaatcgc aacccggata acttctttgc
    25381 tgaaaacgaa caggcggctt tccatcctgg gcatatcgtg ccgggactgg acttcaccaa
    25441 cgatccgctg ttgcagggac gtttgttctc ctataccgat acacaaatca gtcgtcttgg
    25501 tgggccgaat ttccatgaga ttccgattaa ccgtccgacc tgcccttacc ataatttcca
    25561 gcgtgacggc atgcatcgca tggggatcga cactaacccg gcgaattacg aaccgaactc
    25621 gattaacgat aactggccgc gcgaaacacc gccggggccg aaacgcggcg gttttgaatc
    25681 ataccaggag cgcgtggaag gcaataaagt tcgcgagcgc agcccatcgt ttggcgaata
    25741 ttattcccat ccgcgtctgt tctggctaag tcagacgcca tttgagcagc gccatattgt
    25801 cgatggtttc agttttgagt taagcaaagt cgttcgtccg tatattcgtg agcgcgttgt
    25861 tgaccagctg gcgcatattg atctcactct ggcccaggcg gtggcgaaaa atctcggtat
    25921 cgaactgact gacgaccagc tgaatatcac cccacctccg gacgtcaacg gtctgaaaaa
    25981 ggatccatcc ttaagtttgt acgccattcc tgacggtgat gtgaaaggtc gcgtggtagc
    26041 gattttactt aatgatgaag tgagatcggc agaccttctg gccattctca aggcgctgaa
    26101 ggccaaaggc gttcatgcca aactgctcta ctcccgaatg ggtgaagtga ctgcggatga
    26161 cggtacggtg ttgcctatag ccgctacctt tgccggtgca ccttcgctga cggtcgatgc
    26221 ggtcattgtc ccttgcggca atatcgcgga tatcgctgac aacggcgatg ccaactacta
    26281 cctgatggaa gcctacaaac accttaaacc gattgcgctg gcgggtgacg cgcgcaagtt
    26341 taaagcaaca atcaaggtcg ctgaccaggg tgaagaaggg attgtggaag ctgacagcgc
    26401 tgacggtagt tttatggatg aactgctaac gctgatggca gcacaccgcg tgtggtcacg
    26461 cattcctaag attgacaaaa ttcctgcctg atgggaggcg gcgcaattgc gccgcctcaa
    26521 atgatttaca tagtgcgctt tgtttatgcc ggatgcggcg tg
//
LOCUS       DACAOP010000060        26164 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.060, whole genome shotgun sequence.
ACCESSION   DACAOP010000060 DACAOP010000000
VERSION     DACAOP010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26164
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.060"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            50..874
                     /gene="dinD"
                     /locus_tag="IT892_002802"
     CDS             50..874
                     /gene="dinD"
                     /locus_tag="IT892_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein D"
                     /protein_id="HAP3136000.1"
                     /translation="MNEHHQPFEEIKLINANGAEQWSARQLGKLLGYSEYRHFIPVLT
                     RAKEACENSGHTIDDHFEEILDMVKIGSNAKRALKDIVLSRYACYLVVQNGDPAKPVI
                     AAGQTYFAIQTRRQELADDEAFKQLREDEKRLFLRNELKEHNKQLVEAAQQAGVATAT
                     DFAIFQNHGYQGLYGGLDQKAIHQRKGLKKNQKILDHMGSTELAANLFRATQTEEKLK
                     RDGVNSKQQANTTHFDVGSKVMQTIQELGGTMPEELPTPQVSIKQLENSVKITEKK"
     gene            1166..1783
                     /locus_tag="IT892_002803"
     CDS             1166..1783
                     /locus_tag="IT892_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HAP3136001.1"
                     /translation="MLLHILYLVGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKVFLVLDALGLVVFSI
                     IGAQVALDMGHGPIIAVVAAVTTGVFGGVLRDMFCKRIPLVFQKELYAGVSFASAVLY
                     IALQHYVSNHDVVIISTLVFGFFARLLALRLKLGLPVFYYSHEGH"
     gene            complement(1780..3462)
                     /gene="ligB"
                     /locus_tag="IT892_002804"
     CDS             complement(1780..3462)
                     /gene="ligB"
                     /locus_tag="IT892_002804"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418104.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigB"
                     /protein_id="HAP3136002.1"
                     /translation="MKVWMAILISILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQW
                     DDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRK
                     MVDKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSL
                     ISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSL
                     GVFVWAWPDGPQLMSDRLKELATAGFTLTQTYTRAVKNADEVARVRNEWWKAELPFVT
                     DGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLA
                     PVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTP
                     PENRFNSLTCYFASDVCQEQFISRLVWLGSKQVLGLDGIGEAGWRALHQTHRFEHIFS
                     WLLLTPEQLQNTPGIAKSKSAQLWHQFNLARKQPFTRWVMAMGIPLTRAALNASDERS
                     WSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP"
     gene            3720..4343
                     /gene="gmk"
                     /locus_tag="IT892_002805"
     CDS             3720..4343
                     /gene="gmk"
                     /locus_tag="IT892_002805"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAP3136003.1"
                     /translation="MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQP
                     RPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLD
                     IDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY
                     AEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD"
     gene            4398..4673
                     /gene="rpoZ"
                     /locus_tag="IT892_002806"
     CDS             4398..4673
                     /gene="rpoZ"
                     /locus_tag="IT892_002806"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013511051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP3136004.1"
                     /translation="MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEEND
                     KTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR"
     gene            4692..6800
                     /gene="spoT"
                     /locus_tag="IT892_002807"
     CDS             4692..6800
                     /gene="spoT"
                     /locus_tag="IT892_002807"
                     /EC_number="3.1.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GTP
                     diphosphokinase/guanosine-3',5'-bis pyrophosphate
                     3'-pyrophosphohydrolase"
                     /protein_id="HAP3136005.1"
                     /translation="MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEP
                     YITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSK
                     LDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
                     ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILS
                     EIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRV
                     LGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMG
                     VAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFT
                     PEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPG
                     ARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLNEIPQENI
                     QRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPIKGADGV
                     LITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQE
                     FITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLA
                     NIMRKIRVMPDVIKVTRNRN"
     gene            6807..7496
                     /gene="trmH"
                     /locus_tag="IT892_002808"
     CDS             6807..7496
                     /gene="trmH"
                     /locus_tag="IT892_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(18)-2'-O)-methyltransferase
                     TrmH"
                     /protein_id="HAP3136006.1"
                     /translation="MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVG
                     VHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA
                     VDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE
                     AQRQRQNAGMYLRENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEAD
                     ADWWSTMQAAG"
     gene            7502..9583
                     /gene="recG"
                     /locus_tag="IT892_002809"
     CDS             7502..9583
                     /gene="recG"
                     /locus_tag="IT892_002809"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709432.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAP3136007.1"
                     /translation="MKGRLLDTVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRY
                     EDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRMMTCQISDGSGILTMRFFNFSAA
                     MKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQ
                     ATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLETGQH
                     PAQRRLILEELLAHNLSMLALRAGAQRFHAQPLSANDTLKNKLLAALPFKPTGAQARV
                     VAEIEHDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHA
                     NNFRNWFAPLGIKVGWLAGKQKGKARLSQQEAIASGQVQMIVGTHAIFQEQVQFNGLA
                     LVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDE
                     LPPGRTPVTTVAIPDTRRTDIIDRVRHACITEGRQAYWVCTLIEESELLEAQAAEATW
                     EELKLALPELNVGLVHGRMKPAEKQAVMASFKQGELHLLVATTVIEVGVDVPNASLMI
                     IENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQIRLQVLRDSNDGFVIAQ
                     KDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRLARHIHERYPQQAKALIER
                     WMPETERYSNA"
     gene            complement(9749..10954)
                     /gene="gltS"
                     /locus_tag="IT892_002810"
     CDS             complement(9749..10954)
                     /gene="gltS"
                     /locus_tag="IT892_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HAP3136008.1"
                     /translation="MFHLDTLATLVAATLTLLLGRKLVHSVSFLKKYTIPEPVAGGLL
                     VALALLVLKKSMGWEVNFDMSLRDPLMLAFFATIGLNANIASLRAGGRVVGIFLIVVV
                     GLLVMQNAIGIGMASLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFIERYGFTNATEV
                     AMACATFGLVLGGLIGGPVARYLVKHSTTPNGIPDDQEVPTAFEKPDVGRMITSLVLI
                     ETIALIAICLTVGKIVAQLLAGTAFELPTFVCVLFVGVILSNGLSIMGFYRVFERAVS
                     VLGNVSLSLFLAMALMGLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYD
                     AAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAFLVVPMVGAFFIDIVNALVIKL
                     YLMLPIFAG"
     gene            11234..12625
                     /gene="xanP"
                     /locus_tag="IT892_002811"
     CDS             11234..12625
                     /gene="xanP"
                     /locus_tag="IT892_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanP"
                     /protein_id="HAP3136009.1"
                     /translation="MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLL
                     AMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQG
                     TSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
                     VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNP
                     YLRVASLVIAMAAGYALAWFMGMLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLML
                     VFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCF
                     GQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIA
                     ASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGIT
                     AIVLNLIFPPEKQ"
     gene            12746..14455
                     /locus_tag="IT892_002812"
     CDS             12746..14455
                     /locus_tag="IT892_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HAP3136010.1"
                     /translation="MKFIGKLLLYILIALLVVIAGLYFLLQTRWGAEHISAWVSENSD
                     YHLAFGAMDHRFSAPSHIVLENVTFGRDGQPATLVAKSVDIALSSRQLTEPRHVDTIL
                     LENGTLNLTDQTAPLPFKADRLQLRDMAFNSPNSEWKLSAQRVNGGVVPWSPEAGKVL
                     GTKAQIQFSAGSLSLNDVPATNVLIEGSIDNDRVTLTNLGADIARGTLTGNAQRNADG
                     SWQVENLRMADIRLQSEKSLTDFFAPLRSVPSLQIGRLEVIDARLQGPDWAVTDLDLS
                     LRNMTFSKDDWQTQEGKLSMNASEFIYGSLHLFDPIINAEFSPQGVALRQFTSRWEGG
                     MVRTSGNWLRDGKTLILDDAAIAGLEYTLPKNWQQLWMETTPGWLNSLQLKRFSASRN
                     LIIDIDPDFPWQLTTLDGYGANLTLVTDHKWGVWSGSANLNAAAATFNRVDVRRPSLA
                     LTANSSTVNISELSAFTEKGILEATASVSQTPQRQTHISLNGRGVPVNILQQWGWPEL
                     PLTGDGNIQLTASGDIQANAPLKPTVSGQLHAVNAAKQQVTQTMNAGIVSSGEVTSTE
                     PVR"
     gene            complement(14508..16826)
                     /gene="yicI"
                     /locus_tag="IT892_002813"
     CDS             complement(14508..16826)
                     /gene="yicI"
                     /locus_tag="IT892_002813"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HAP3136011.1"
                     /translation="MKISDGNWLIQPGLNLIHPLQVFEVEQQDNEMVVYAAPRDVRER
                     TWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAE
                     FKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGE
                     TVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYMTNRGYGVLVNHPQCVSF
                     EVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLNTS
                     FTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRR
                     LKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNP
                     DACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWN
                     VLKDTVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFW
                     SHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTQLK
                     CRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEAG
                     DVQFYLPEGRWTHLWHNDELDGSRWHKQQHGFLSLPVYVRDNTLLALGNNDQRPDYVW
                     HEGTALHLFNLQDGHEAVCEVPAADGSVIFTLKAARTGNTITVTGAGEAKNWTLCLRN
                     VVKVNGLQDGSQAESEQGLVVKPQGNALTITL"
     gene            complement(16836..18218)
                     /locus_tag="IT892_002814"
     CDS             complement(16836..18218)
                     /locus_tag="IT892_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418114.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide family
                     transporter"
                     /protein_id="HAP3136012.1"
                     /translation="MKSEVLSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDIFGIPA
                     GFVGTMFLVARALDAISDPCMGLLADRTRSRWGKFRPWVLFGALPFGIVCVLAYSTPD
                     LSMNGKMIYAAITYTLLTLLYTVVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGM
                     LSTVLMMPLVNLIGGDNKPLGFQGGIAVLSVVAFMMLAFCFFTTKERVEAPPTTTSMR
                     EDLRDIWQNDQWRIVGLLTIFNILAVCVRGGAMMYYVTWILGTPEVFVAFLTTYCVGN
                     LIGSALAKPLTDWKCKVTIFWWTNALLAVISLAMFFVPMQASITMFVFIFVIGVLHQL
                     VTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLAFGGALIGWMLAYGGYDA
                     AEKAQNSATISIIIALFTIVPAICYLLSAIIAKRYYSLTTHNLKTVMEQLAQGKRRCQ
                     QQFTSQEVQN"
     gene            18511..18605
                     /locus_tag="IT892_002815"
     tRNA            18511..18605
                     /locus_tag="IT892_002815"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18545..18547,aa:Sec,seq:tca)
     gene            18714..18860
                     /locus_tag="IT892_002816"
     CDS             18714..18860
                     /locus_tag="IT892_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001626279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HAP3136013.1"
                     /translation="MDDERLKNPPVGSSVLERIRDIHASMRRVYLQVICPPADSQPTV
                     SPLR"
     gene            19242..20426
                     /locus_tag="IT892_002817"
     CDS             19242..20426
                     /locus_tag="IT892_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter"
                     /protein_id="HAP3136014.1"
                     /translation="MQKTATTPSKILDLTAAAFLLVAFLTSIAGALQTPTLSIFLADE
                     LKARPIMVGFFFTGSAIMGILVSQFLARHSDKQGDRKLLILLCCLFGVLACTLFAWNR
                     NYFILLSTGVLLSSFASTANPQMFALAREHADRTGRETVMFSTFLRAQISLAWVIGPP
                     LAYELAMGFSFKVMYLTAAIAFVVCGLIVWLFLPSIQRNIPVVTQPVEILPSTHRKRD
                     TRLLFVVCSMMWAANNLYMINMPLFIIDELHLTDKLAGEMIGIAAGLEIPMMLIAGYY
                     MKRIGKRLLMLIAIVSGMCFYASVLMATTPAVELELQILNAIFLGILCGIGMLYFQDL
                     MPEKIGSATTLYANTSRVGWIIAGSVDGIMVEIWSYHALFWLAIGMLGIAMICLLFIK
                     DI"
     gene            20537..21460
                     /locus_tag="IT892_002818"
     CDS             20537..21460
                     /locus_tag="IT892_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HAP3136015.1"
                     /translation="MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSQMSSQFLTMTRL
                     IFAGLILLTLSFVHGDKIFSIINNHKDAISLLIFSVVGALTVQLTFLLTIEKSNAATA
                     TVLQFLSPTIIVAWFSLVRKSRPGILVFCAILTSLVGTFLLVTHGNPTSLSISPAALF
                     WGIASAFAAAFYTTYPSTLIARYGTLPVVGWSMLIGGLILLPFYARQGTNFVVNGSLI
                     LAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGITFTLPDW
                     LGTLLILSSVILISMDSRRRARKINRPARHK"
     gene            complement(21464..22282)
                     /gene="nlpA"
                     /locus_tag="IT892_002819"
     CDS             complement(21464..22282)
                     /gene="nlpA"
                     /locus_tag="IT892_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpA"
                     /protein_id="HAP3136016.1"
                     /translation="MKLTTHHLRTGAALLLAGILLAGCDQSSSDAKHIKVGVINGAEQ
                     DVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNHGELDANVFQHRPFLEQDNQAHGY
                     KLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKE
                     GKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIQQTGLSPVHDS
                     VFIEDKNSPYVNILVAREDNKNAENVKEFLQSYQSPEVAKAAETIFNGGAVPGW"
     gene            22504..22797
                     /locus_tag="IT892_002820"
     CDS             22504..22797
                     /locus_tag="IT892_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136017.1"
                     /translation="MKPTTLLLIFTFFAMPGIVYAESPFSSLQSAKEKTTVLQDLRKI
                     CTPQASLSDEAWEKLMLSDENNKQHIREAIVAMERNNQSNYWEALGKVECPDM"
     gene            complement(22838..24028)
                     /gene="nepI"
                     /locus_tag="IT892_002821"
     CDS             complement(22838..24028)
                     /gene="nepI"
                     /locus_tag="IT892_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine ribonucleoside efflux pump NepI"
                     /protein_id="HAP3136018.1"
                     /translation="MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLT
                     PMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLV
                     SFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIA
                     APLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGV
                     MAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFIL
                     KRSVKLALAGAPLILAVSALVLTLWGSDKIVATGVAIIWGLTFALVPVGWSTWITRSL
                     ADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVK
                     MKKS"
     gene            complement(24239..24691)
                     /locus_tag="IT892_002822"
     CDS             complement(24239..24691)
                     /locus_tag="IT892_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1198 domain-containing protein"
                     /protein_id="HAP3136019.1"
                     /translation="MIWIMLATLAVVFVVGFRVLTSGARKAIRRLSDRLNIDVVPVES
                     MVDQMGKSAGDEFLRYLHRPDESHLQNAAQVLLIWQIVIVDGSEQNLLQWHRILQKAR
                     LAAPITDAQVRLALGFLRETEPEMQDINAFQMRYNAFFQPAEGVHWLH"
     gene            complement(24744..26078)
                     /locus_tag="IT892_002823"
     CDS             complement(24744..26078)
                     /locus_tag="IT892_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP3136020.1"
                     /translation="MNNDNTDYVSNESGTLSRLFKLPQHGTTVRTELIAGMTTFLTMV
                     YIVFVNPQILGAAQMDPKVVFVTTCLIAGIGSIAMGIFANLPVALAPAMGLNAFFAFV
                     VVGAMGISWQTGMGAIFWGAVGLFLLTLFRIRYWMISNIPLSLRIGITSGIGLFIALM
                     GLKNTGVIVANKDTLVMIGDLSSHGVLLGILGFFIITVLSSRHFHAAVLVSIVVTSCC
                     GLFFGDVHFSGVYSIPPDISGVIGEVDLSGALTLELAGIIFSFMLINLFDSSGTLIGV
                     TDKAGLIDGNGKFPNMNKALYVDSVSSVAGAFIGTSSVTAYIESTSGVAVGGRTGLTA
                     VVVGVMFLLVMFFSPLVAIVPPYATAGALIFVGVLMTSSLARVNWDDFTESVPAFITT
                     VMMPFTFSITEGIALGFMSYCIMKVCTGRWRDLNLCVVVVAALFALKIILVD"
BASE COUNT         6677 a         6917 c         6388 g         6182 t
ORIGIN      
        1 acagttacag atttactttc tttgcaattg atatcacatg gagtgggcaa tgaacgaaca
       61 tcatcaacct tttgaagaga taaaactgat taatgcaaac ggagcagaac aatggtcagc
      121 aagacaactt gggaaactac tgggttattc agagtatcgt cactttatac ctgtattaac
      181 gcgcgccaaa gaagcctgtg agaacagtgg tcacacaatt gatgaccatt tcgaggagat
      241 cctcgatatg gtcaaaattg gctcaaatgc caaaagagca ttaaaagaca tcgtactctc
      301 ccgctatgcc tgttacctgg tagtacaaaa cggcgaccct gcgaaaccgg tcattgcggc
      361 agggcagact tattttgcta tccagacccg acggcaggag cttgctgacg atgaagcatt
      421 taagcaactt cgtgaagacg aaaagcgtct gtttctgaga aatgagttga aagaacataa
      481 caaacaattg gttgaggcag cacagcaagc tggggtagcg acagctactg atttcgccat
      541 atttcagaat catggttacc aggggctgta tggtggatta gatcagaaag ctattcatca
      601 gcggaagggg ctgaaaaaga atcagaagat cctggatcat atgggttcaa cagaactggc
      661 ggctaatctc tttcgagcta cccaaacaga agaaaaactc aagcgggatg gcgtgaattc
      721 aaaacagcaa gctaatacca cacactttga cgtgggtagc aaggtgatgc aaaccattca
      781 ggaacttggc ggaaccatgc ctgaggagtt gccgaccccg caggtcagca tcaagcagtt
      841 ggaaaacagt gtaaaaatta cagagaagaa atagcagaaa ctaaaaactc tttttgttga
      901 ttgagatacc cgatgcgtaa gccaaagtcc aggtgcggtg aacacaatgg ctaaacattg
      961 cacctttctt ttccacccct caattttaac ctattttttc ttatgcattt tctcagacaa
     1021 gaagtcagaa gaatgcatct acgctacaga aaatagcgat ttcacataac tacaagttat
     1081 caatttcctc tcaccttaaa aaatctcaat cgtgacaata cgcacaaatc gctaccctgc
     1141 cagacagatt tttagggaga gaaccatgct gttacacatt ttgtatttgg ttggcattac
     1201 tgccgaagcc atgacggggg ctctggcggc cgggcgacgc cgcatggata catttggcgt
     1261 aattattatt gcgaccgcca ccgcaattgg cggagggtca gtgcgcgata ttctgctggg
     1321 ccactatccg ctcggctggg tcaaacaccc ggaatatgtg attatcgtcg ctaccgccgc
     1381 agtactcacc actatcgttg ctcctgtaat gccttacctg cgcaaagtgt ttctggtgct
     1441 cgatgcgctt ggactggtgg tcttttctat catcggcgca caggttgcac tggatatggg
     1501 gcacggccca attattgccg ttgtcgcggc ggtaaccacc ggcgtgtttg gcggcgtttt
     1561 gcgcgatatg ttctgtaaac gtatcccact ggtattccag aaagagttgt atgccggtgt
     1621 ctcatttgcc tccgccgtgc tgtacatcgc gctgcaacac tatgtttcta accatgatgt
     1681 ggtaattatc tccaccctgg tattcggctt ttttgcccgc ttactggcgc tacgccttaa
     1741 gctgggatta ccggtctttt actacagcca cgaaggacac taaggttcaa aacctgtgat
     1801 ctgctgggca gccagccaac tgcccagctt cttgatttgc gcattttcct tccattcaat
     1861 aacctgtctg gcgcgtcccg atccagtccc cggcagctgc tgccagaact gctccgtgct
     1921 aaataaaagt tgcgaccagg accgttcatc actggcatta agcgccgccc gggttagcgg
     1981 tattcccatt gccatcaccc agcgagtaaa aggctgctta cgagccagat taaactgatg
     2041 ccatagctgc gcacttttac ttttcgcgat ccccggcgtg ttctgtaatt gctctggcgt
     2101 taataaaagc caggaaaaga tatgttcaaa gcgatgagtc tgatgcagcg cgcgccaacc
     2161 ggcctcacca atgccatcca gccccagaac ctgttttgac cccagccaga ctaagcgtga
     2221 aatgaactgt tcctgacaaa catcagaagc aaagtagcag gtcaacgagt taaagcggtt
     2281 ttctggtggt gtcggttttg tacgttctgc accgcgccag accacatcat caatgcgagg
     2341 aataccctga ccggcaaggc tgacgaggat ctgatcacca ggcgcaatat cccactcctg
     2401 ccagcgcctg acggaaccaa tattcacccg ctggactttt ttatcatcca gcatgacagg
     2461 tgcgagtgac gcaaccaccg atattttacc gctcttaccc accgcaaact gaatcgcctt
     2521 cacttcggca acctgagcta caggttgata tttccaggcc accagccact ctgcctggcc
     2581 cggtagccaa tggcgggatt ctggctcttt cgccgctcgt acaactacgc catcggtgac
     2641 gaagggtaat tccgctttcc accactcatt gcgtacgcgc gcaacttcat cagcattttt
     2701 caccgcacgg gtatacgtct gcgttagagt aaaacctgcg gtagccagct cttttaaacg
     2761 atcagacatt aactgcggtc catccggcca tgcccagaca aaaacgccca gagaattcag
     2821 cgtgtcgcta tcgtcctggc gcatcatcaa gccagcaact tttgcgcggg catttattcc
     2881 ccccatttgt tgttggatat gcccctcgcg ctggagaaat atttccccct gaagcgtact
     2941 gttggctaaa ggcccgctaa cggtttgcgg cacagcggaa attaagctaa ctttctgcgt
     3001 ccagtcctcg cctttcaggc cattaccgcg actgattgct ttgttcagtt tcccgtcccg
     3061 ataaaccagg gttaccgcaa cgccatcaac ttttggctgc acccaaagat cgctacgttc
     3121 tcgcatccac agacttaatg cgtttttatc caccattttg cgtacacccg tatgggcaac
     3181 cggatgcata accgcaccat ttaaaggcgg catcatcacg tcgcggggct cgctcccaaa
     3241 gcagcgttgc cactgcgtaa gacgggcgct taactgatcg taaacaccgt cttccacctc
     3301 actttttcct tccttccaat agtcatcgtc ccactgtttt atttgctgtt gcaggcggga
     3361 aatttcttcc tgtgctctgg ctggcgacca ggccggacag accgcccaca cagatgattg
     3421 ccagcacaag atacttatta atatcgccat ccatactttc atcatcacct ccgctgtagg
     3481 tagtcaggca gatatacaac gtgatgaaag caaagccgag tggcaaaaac ggagtctgcg
     3541 aggacgcttc ctgaaaatcg tctttattgc agtgaatgac aggcaaatgc ggaagcagct
     3601 acgcaaaacg caacaacttt gcgcaaaaag tgtgagcaag ggctacgtca catggccgcg
     3661 ccgtgtataa taagctcgta tgtaggcttt atttcgctaa tcacatacga aagatactca
     3721 tggctcaagg cacgctttat attgtttctg cccccagtgg cgcgggtaaa tccagcctga
     3781 ttcaggcttt attaaaaacc caaccgttgt atgacaccca ggtttctgtt tcacacacca
     3841 cacgccaacc gcgtcctggt gaagtccacg gtgaacatta tttctttgtt aatcatgatg
     3901 aatttaaaga aatgattagc agagatgcgt tcctcgaaca cgcagaagtt tttggtaatt
     3961 actatggcac ttcgcgtgag gccattgagc aagtactggc gaccggtgtc gatgtttttc
     4021 tcgatatcga ctggcagggc gcgcagcaaa ttcgccagaa gatgccgcac gcccggagta
     4081 tctttatttt accgccgtcc aaaattgaac tggaccgccg tctacgcggt cgcggtcagg
     4141 acagcgaaga ggtcattgca aagcgtatgg cgcaagctgt tgcagaaatg agccattacg
     4201 ccgaatatga ttatctgatt gtgaatgatg acttcgatac cgcgttgacc gatttgaaga
     4261 ccattattcg cgccgaacgt ctgcgcatga gccgccaaaa gcagcgtcat gacgctttaa
     4321 tcagcaaatt gttggcagac tgaacctgat ttcagtatca tgcccagtca tttcttcacc
     4381 tgtggagctt tttaagtatg gcacgcgtaa ctgttcagga cgctgtagag aaaattggta
     4441 accgttttga cctggtactg gtcgccgcgc gtcgcgctcg tcagatgcag gtaggcggaa
     4501 aggatccgct ggtaccggaa gaaaacgata aaaccactgt aatcgcgctg cgcgaaatcg
     4561 aagaaggtct gatcaacaac cagatcctcg acgttcgcga acgccaggaa cagcaagagc
     4621 aggaagccgc tgaattacaa gccgttaccg ctattgctga aggtcgtcgt taatcacaaa
     4681 gcgggtcgcc cttgtatctg tttgaaagcc tgaatcaact gattcaaacc tacctgccgg
     4741 aagaccaaat caagcgtctg cggcaggcgt atctcgttgc acgtgatgct cacgaggggc
     4801 aaacacgttc aagcggtgaa ccctatatca cgcacccggt agcggttgcc tgcattctgg
     4861 ccgagatgaa actcgactat gaaacgctga tggcggcgct gctgcatgac gtgattgaag
     4921 atactcccgc cacctaccag gatatggaac agctttttgg taaaagcgtc gccgagctgg
     4981 tagagggggt gtcgaaactt gataaactca agttccgcga taagaaagag gcgcaggccg
     5041 aaaactttcg caagatgatt atggcgatgg tgcaggatat ccgcgtcatc ctcatcaaac
     5101 ttgccgaccg tacccacaac atgcgcacgc tgggctcact tcgcccggac aaacgtcgcc
     5161 gcatcgcccg tgaaactctc gaaatttaca gcccgctggc gcaccgttta ggtatccacc
     5221 acattaaaac cgaactcgaa gagctgggtt ttgaggcgct gtatcccaac cgttatcgcg
     5281 taatcaaaga agtggtgaaa gccgcgcgcg gcaaccgtaa agagatgatc cagaagattc
     5341 tttctgaaat cgaagggcgt ttgcaggaag cgggaatacc gtgccgcgtc agtggtcgcg
     5401 aaaagcatct ttattcgatt tactgcaaaa tggtgctcaa agagcagcgt tttcactcaa
     5461 tcatggacat ctacgctttc cgcgtgatcg tcaatgattc tgacacctgt tatcgcgtgc
     5521 tgggccagat gcacagcctg tacaagccgc gtccgggccg cgtgaaagac tatatcgcca
     5581 ttccaaaagc gaacggctat cagtctttgc acacctcgat gattggcccg cacggcgtgc
     5641 cggttgaggt ccagatccgt accgaagata tggatcagat ggcggagatg ggtgttgccg
     5701 cgcactgggc ttataaagag cacggcgaaa ccagtactac cgcacaaatc cgcgcccagc
     5761 gctggatgca aagcctgctg gagctgcaac agagcgccgg tagttcgttt gaatttatcg
     5821 agagcgttaa atccgatctc ttcccggatg agatttacgt tttcacaccg gaagggcgca
     5881 ttgtcgagct gcctgccggt gcaacgcccg tcgacttcgc ttatgcagtg cataccgata
     5941 tcggtcatgc ctgcgtgggc gcacgcgttg accgccagcc ttacccgctg tcgcagccgc
     6001 ttaccagcgg tcaaaccgtt gaaatcatta ccgcaccggg cgctcgcccg aatgccgcgt
     6061 ggctgaactt tgtcgttagc tcaaaagcgc gcgccaaaat tcgtcagttg ctgaaaaacc
     6121 tcaagcgtga tgattctgta agcctgggcc gtcgtctgct caaccatgct ttgggtggta
     6181 gccgtaagct gaatgaaatc ccgcaggaaa atattcagcg cgagctggat cgcatgaagc
     6241 tggcaacgct tgacgatctg ctggctgaaa tcggccttgg taacgcaatg agcgtggtgg
     6301 tcgcgaaaaa tctacaacat ggggacgcct ccattccacc ggcaacccaa agtcacggac
     6361 atctgccaat taaaggtgcc gatggcgtgc tgatcacctt tgcgaaatgc tgccgcccta
     6421 ttcctggcga cccgattatc gcccacgtca gccccggtaa aggtctggtg atccaccatg
     6481 aatcctgccg taacatccgt ggctaccaga aagagccaga gaagtttatg gctgtggaat
     6541 gggataaaga gacggcgcag gaattcatca ccgaaatcaa ggtggagatg ttcaatcatc
     6601 agggtgcgct ggcaaacctg acggcggcaa ttaacaccac gacctcgaat attcaaagtt
     6661 tgaatacgga agagaaagat ggtcgcgtct acagcgcctt tattcgtctg accgctcgtg
     6721 accgtgtgca tctggcgaat atcatgcgca aaatccgcgt gatgccagac gtgattaaag
     6781 tcacccgaaa ccgaaattaa tgttttatga acccaacacg ttatgcacgc atctgcgaaa
     6841 tgctcgccag gcggcagcct gacctgaccg tctgcatgga gcaggtccac aaacctcata
     6901 acgtttctgc gattattcgt accgcagatg ccgttggcgt acatgaagtt cacgccgtct
     6961 ggcctggtag ccggatgcgc accatggctt cggcagcggc gggtagtaac agctgggtac
     7021 aggtgaaaac acaccgcacc attggcgatg ccgtcgctca tctgaaaggc cagggcatgc
     7081 agattctggc aacccatctt tctgataatg ctgtcgattt ccgcgaaatt gattacactc
     7141 gcccgacctg cattttgatg ggacaggaga aaacgggcat cacgcaggaa gcattggccc
     7201 tggcggatca ggacatcatc attccgatga tcggcatggt gcagtcgctg aatgtttccg
     7261 ttgcctcagc cctcattctt tacgaagccc agcgtcagcg gcaaaatgca ggcatgtacc
     7321 tgcgtgaaaa cagcatgttg ccggaagcag agcaacaacg cctgttgttt gaaggcggct
     7381 atccggtgct ggcgaaagtc gcaaaacgca aaggcctgcc ttacccccac gtcaatcagc
     7441 aaggcgagat cgaagctgat gctgactggt ggtccaccat gcaggccgca gggtaagcgc
     7501 catgaaaggc cgcctgttag atactgtccc gctcagttcc ctaacgggcg ttggcgcagc
     7561 gcttagtaac aaactggcga aaatcaacct gcataccgtg caggatttac tcttacacct
     7621 tcccctgcgc tacgaagatc gcacccatct ctaccccatc ggagaactac tgccgggcgt
     7681 ttatgccacg gtggaaggcg aagtgctgaa ctgcaatatc tccttcggcg gtcggcggat
     7741 gatgacctgc cagatcagcg acggttccgg catcctcacc atgcgctttt tcaatttcag
     7801 cgcggcaatg aaaaatagcc tggcgacggg ccgccgtgta ctggcttatg gcgaagcaaa
     7861 gcgcggtaaa tatggtgcgg agatgatcca cccggaatac cgcgtgcagg gcgatctcag
     7921 cacgccagaa ttacaggaaa cgctcacgcc ggtttatcca acaacggaag gcgtaaagca
     7981 ggccacgctg cgtaaattaa ccgaccaggc gctggatctg ctcgacacct gcgccattga
     8041 agaactcctg ccgccggaac tgtcacaagg aatgatgacg ctaccggaag cgttgcgcac
     8101 tttgcaccgc ccgccaccga cgctacagct tagcgatctg gaaaccgggc agcatccggc
     8161 gcaacgtcgt ctgattctgg aagaactgct ggcgcacaac ctcagcatgt tagccttacg
     8221 tgccggagca cagcgttttc atgcccagcc gctgagcgcc aatgacacgc tgaaaaataa
     8281 actcctcgcc gccttaccgt tcaagccaac gggcgcacag gcacgcgtag tggcggagat
     8341 cgagcatgat atggcgctgg atgtgccgat gatgcgcctg gtacagggcg atgtaggttc
     8401 cggtaaaacg ctggtcgccg ccctcgccgc gctgcgtgcg attgcccacg gcaaacaggt
     8461 ggcactgatg gcaccaaccg aattactcgc cgagcagcac gccaataact tccgcaactg
     8521 gtttgcaccg ctcggtatca aagtgggctg gctcgccggt aagcagaaag gcaaagcgcg
     8581 actgtctcag caggaagcca tcgccagcgg tcaggtgcag atgattgtcg gtacacacgc
     8641 catcttccag gaacaggtgc agtttaacgg cctggcgctg gtgattatcg acgaacagca
     8701 tcgttttggc gtgcatcagc gtctggcatt gtgggagaaa ggccagcagc agggcttcca
     8761 tccgcatcag ttgatcatga ccgccacgcc gatcccccgc acgctggcaa tgacggcgta
     8821 tgccgatctc gatacctcgg tgatagatga gctgccgcca ggccgcacgc cagtgactac
     8881 ggtcgctatt cctgataccc gccgtaccga catcattgac cgcgtgcgcc acgcctgcat
     8941 aactgaaggt cgtcaggcgt actgggtttg tacgttgatt gaagagtcag agttactgga
     9001 agcgcaggcg gcggaagcta cctgggaaga gttgaaactg gcgctaccag aattgaatgt
     9061 tggcctggta cacgggcgga tgaaaccagc cgagaaacag gcggtgatgg cgtcgtttaa
     9121 acaaggtgag ctacatctgc tggttgccac taccgttatt gaagtcggtg ttgatgtgcc
     9181 taacgccagc ctgatgatta tcgaaaaccc tgagcgtctg ggtctggcgc agttacacca
     9241 gctgcgcggg cgcgtaggtc gtggcgcggt ggcttctcac tgcgtgctgc tctacaaaac
     9301 gccgctttct aaaacggcgc aaattcgcct gcaagtgctg cgcgacagta acgacggttt
     9361 tgtgattgcg caaaaagatc tggagattcg cggccctggc gaattgttag gcacgcgtca
     9421 gacgggtaat gctgaattta aagtggcgga tttactgcgc gatcaggcga tgatcccgga
     9481 agttcagcgc ctggcgcgac atattcacga acgttaccca caacaggcaa aagccttgat
     9541 agaacgctgg atgccggaga cagaacgtta ctcgaatgcg taaaaggcgg cagtgagaag
     9601 accgccattt caggttaccc taccttcctg ccggatgcga ttcaccctac aaattcaata
     9661 aattatgaat caatacgcag gcttgataag cgaagcgtat caggcatttg tctttgttgc
     9721 ggcggcactt ctaccgccgc ttcatcggtt aaccggcaaa aatcggcaac atcaaataca
     9781 acttaattac cagcgcattg acgatatcga taaagaacgc accgaccatc ggcaccacca
     9841 aaaacgccat gtgcgacggg ccaaagcgtt cagtgatcgc ctgcatgttg gcgattgccg
     9901 ttggcgttgc accgaggcca aaaccacagt gacccgcagc cagcactgcc gcatcgtagt
     9961 ttttgcccat catgcgccag gtaacgaaga tggcatacaa cgccatgaag atggtctgta
    10021 ccaccagaat cgccagcatc ggcagcgcca gcgaagccag ctcccacagt ttcagcccca
    10081 tcaacgccat cgccaggaac aacgacaagc ttacgttacc cagcacggat accgcacgct
    10141 caaagacgcg gtaaaagccc attattgaca gaccgttgct cagaatcacg ccaacaaaca
    10201 gtacacagac gaaggtcggc agttcaaaag cagtgccagc caaaagttgc gcaacaattt
    10261 tccccaccgt caggcagata gcaatcagcg cgatagtttc aatcagcacc aacgaggtga
    10321 tcatgcggcc cacatccggc ttttcaaacg ccgtcgggac ttcctggtca tccggaatac
    10381 cgttcggcgt ggtggagtgt ttcaccagat agcgcgccac cggaccgcca atcaagccgc
    10441 ccagcaccag accgaacgtt gcacaggcca tcgccacttc cgtcgcattg gtgaagccat
    10501 aacgttcaat gaacaattta ctccacgcag cgcccgtacc gtgaccgccg gaaagcgtaa
    10561 tagaaccggc caacagcccc atcagcggat caagccctaa caggctagcc ataccaatgc
    10621 caatggcatt ttgcatcacc aacagaccaa caaccacaat caagaagatg ccaaccacac
    10681 gcccaccggc acgcaaactg gcaatgttgg cgttcaggcc aatggtggcg aagaaagcca
    10741 gcattaacgg atcgcgcagg gacatatcaa agttgacttc ccagcccatg ctttttttca
    10801 gtactagtag cgccagcgcc accaacaaac cacccgcaac aggttccggt atggtgtatt
    10861 tcttcaaaaa ggagacggaa tggaccaact tacgcccgag cagcaacgtc agcgttgcgg
    10921 caacaagcgt tgctaaagta tcgagatgaa acatagttac tcctttgtat ccgcatcact
    10981 ctttcatact cgtcatactt catcgcgcag tggcaacttc atgaactatg acgggtatcg
    11041 agttatgctt tcctgggtca aattctcagc tgttaatgaa caaatggcat ggattttaag
    11101 cagaaaaata ccaaaagtta tataaaaaag tgcatttatc tcatttaaat atttagatga
    11161 ggatgtggca aacgtttgct tttctctttc ggtcagctaa aatgcccgct ttgctaccac
    11221 gggattgttt tcgatgtctg tttccaccct cgagtcagaa aatgcgcaac cggttgcgca
    11281 gactcaaaac agcgaactga tttaccgtct tgaagatcgt ccgccgcttc ctcaaaccct
    11341 gtttgccgcc tgtcagcatc tgctggcgat gttcgttgcg gtgatcacgc cagcgctatt
    11401 aatctgccag gcgctgggtt taccggcaca agacacgcaa cacattatta gtatgtcgct
    11461 gtttgcctcc ggtgtggcat cgattattca aattaaggcc tggggtccgg ttggctccgg
    11521 gctgttgtct attcagggca ccagcttcaa ctttgttgcc ccgctgatta tgggcggtac
    11581 cgcgctgaaa accggtggtg ctgatgttcc taccatgatg gcggctttgt tcggcacgtt
    11641 gatgctggca agttgcaccg agatggtgat ctcccgcgtt ctgcatctgg cgcgccgcat
    11701 tattacgccg ctggtttctg gcgttgtggt gatgattatc ggcctgtcgc taattcaggt
    11761 tgggttaacg tccattggcg gcggttacgc agccatgagc gataacacct tcggcgcacc
    11821 gaaaaatctg ctgctggcag gcgtggtctt agccttaatt atcctgctta accgtcaacg
    11881 taacccttac ttacgcgtgg cctcactggt gattgcgatg gcggccggat atgcgctggc
    11941 gtggtttatg ggcatgttgc cagaaagcaa cgaaccgatg acgcaagaac tgattatggt
    12001 gccaacgccg ctctattacg gtcttggcat tgaatggagt ctgctgctgc cgctgatgct
    12061 ggtctttatg atcacttcgc tggaaaccat tggcgatatc acggcgacct ctgacgtttc
    12121 cgaacagcca gtgtccggtc cgctgtacat gaaacgcctg aaaggtggcg tgctggcaaa
    12181 cggcctgaac tcgtttgttt cggcggtgtt taacaccttc ccgaactcct gcttcgggca
    12241 aaacaacgga gtgatccagt tgactggtgt tgccagccgc tatgtcggtt ttgtcgtcgc
    12301 gctgatgttg atcgtgctgg gtctgttccc ggcagtgagc ggttttgtac aacacattcc
    12361 agaaccggtt ctgggcggcg caacgcttgt aatgtttggc accatcgccg cctccggtgt
    12421 gcgtatcgtt tctcgtgagc cgctgaaccg tcgggcgatt ctgattatcg cgctgtcgct
    12481 ggcggttggt ctgggcgtgt ctcagcagcc gctgattttg cagtttgccc ctgaatggct
    12541 gaaaaacctg ctctcctccg ggatcgccgc gggcggtatt actgccatcg tgctgaatct
    12601 gattttccca ccagaaaaac agtaattcac tggcggcggt aagataatta ccgccgcagt
    12661 ctcacctctt tcaccattcc cgccttgagg attgcgcgta aatcgtgcat aactccctta
    12721 tgtgcatttc acgggatgga agaccatgaa atttattggg aagctgcttc tctacattct
    12781 catcgctctg ttagtggtga tcgctggcct ctattttctt ctgcaaaccc gctggggagc
    12841 agaacatatc agcgcatggg tttccgagaa tagcgactat catctggcct tcggggcgat
    12901 ggatcaccgt ttttccgcgc catctcatat cgtgctggag aatgtcacgt ttggtcgtga
    12961 tggccagccc gcgaccctgg tggccaaaag tgtcgacatt gcgctaagta gtcggcaact
    13021 gaccgaacca cgccatgtcg ataccatcct gctggaaaac gggacgctga atctcaccga
    13081 ccagaccgcg ccgctaccgt tcaaagccga tcgtctgcaa ctgcgtgata tggcgtttaa
    13141 tagcccgaat agcgaatgga aactgagcgc gcagcgggta aatggcggcg tggttccgtg
    13201 gtcaccagaa gccggtaaag tgctgggtac gaaggcgcag attcagttta gtgccggatc
    13261 gctttcgctc aatgatgttc ctgccaccaa tgtactgatt gaaggcagta ttgataacga
    13321 tcgcgttacg ctgactaacc tgggtgccga catcgcgcgc gggacattaa ccggaaacgc
    13381 gcagcgtaac gccgacggca gctggcaagt ggaaaacctg cgcatggcgg atatccgtct
    13441 acaaagcgaa aaatcgctaa ccgacttctt tgcgccatta cgctctgtcc cgtcgttgca
    13501 gattggtcgc ctggaagtga tcgatgctcg tttgcaaggt ccggactggg cggtgaccga
    13561 cctcgatctc agcttgcgca acatgacctt cagtaaagat gactggcaga cacaagaagg
    13621 caaactgtcg atgaacgcta gcgagttcat ttatggttcg ctgcatttat ttgacccgat
    13681 tataaacgcg gaattttccc cgcagggcgt agcgctgcgc cagttcacca gccgctggga
    13741 agggggtatg gtcagaacgt cagggaactg gctgcgtgac gggaaaacgt tgatccttga
    13801 tgatgcggca attgccgggc tggaatatac cttgccgaaa aactggcaac agttgtggat
    13861 ggaaacgaca cccggttggt taaacagcct gcaactgaag agatttagcg ccagccgcaa
    13921 tctgatcatt gatatcgacc ctgacttccc gtggcagctc accacgctcg atggttacgg
    13981 tgccaacctg acgctggtta ccgatcataa atggggcgtc tggagtggct cggcgaatct
    14041 gaatgccgcc gccgcgacat tcaatcgtgt tgatgttcgt cgcccgtcgc tggcgctgac
    14101 cgccaacagc agcacggtga atatcagcga actgagtgca tttactgaaa aaggcattct
    14161 ggaagccact gccagtgttt cacaaacgcc acaacgtcag acccatatca gcctgaatgg
    14221 acgcggtgtg ccggtgaata ttttgcaaca atggggatgg cctgaattac cgttgactgg
    14281 cgacggcaat attcagctta ccgccagtgg agatattcag gccaatgccc cgctgaaacc
    14341 tacggttagc gggcaattgc atgccgtgaa cgccgcaaag cagcaagtga ctcaaaccat
    14401 gaatgctggc atcgtttcca gcggtgaagt tacatcgacg gagccggtgc ggtaaacatc
    14461 aatctcgccg ggtacgactc agacgtaccc ggcattccat caatagatta caacgtaatt
    14521 gtcagcgcat tcccttgagg cttcaccacc agcccctgct cactttcagc ctgcgaaccg
    14581 tcttgcagac catttacttt cacaacattg cgcaggcaca gtgtccagtt cttcgcctcg
    14641 cccgcaccag tcacagtaat cgtgttgcca gtacgtgctg cttttaaagt aaagatcacc
    14701 gatccgtcag cagcgggcac ttcacagacg gcttcatgcc cgtcttgcag attaaagagg
    14761 tggagtgccg tgccttcgtg ccacacgtaa tcgggacgtt gatcgttgtt gcccagcgcc
    14821 agtagagtgt tatcacgcac ataaacgggc agactcagga agccgtgctg ctgtttatgc
    14881 cagcgactac cgtcgagttc atcgttgtgc cacaggtgtg tccagcgacc ttccggcagg
    14941 tagaactgca catcgcccgc ttcagtgaac accggcgcaa ccatcacgtt gtcgcctaac
    15001 atgtattgac ggtcaaggta atcacaagcc ggatcgtccg ggaactccat catcatggcc
    15061 cgcatcatcg gcgtaccccg cgcgttcgca cgcgcagctt cacgatacag atacggcatc
    15121 atgcggcatt tcagttgcgt gaagaagcgc accacatcac aggactcatc atcgtaggcc
    15181 cacggcacac gataagattt gctaccgtgt aaacggctat ggctggagag caaaccaaac
    15241 gcgcaccagc gtttgtaaac gtgcgccgga gcggtatttt caaagccgcc gatatcgtgg
    15301 ctccagaagc caaaacctga aaggccaata gacaaaccac cgcgcaggct ttccgccatt
    15361 gattcgtagt tagcgtaaca atcgccaccc cagtgtaccg ggaatttctg cgcaccgacg
    15421 gaggccgagc gggcaaacaa gacagcttct tcctcaccaa cggtgtcctt gagcacgttc
    15481 cacaccagtt cgttgtagat gtacgcataa tggttatgca ttttctgcgg atcggaaccg
    15541 tcaaaccact gaacatcagt tgggatacgt tcgccaaagt cggtcttaaa gcaatcaacg
    15601 cccatcgcga ccagaccttt cagtttgtcg gcgtaccatt tgcaggcatc cggattggta
    15661 aagtcataaa tcgccagacc tggctgccat ttatcccact gccatagcga accgtccggg
    15721 cgtttgagta aatagccttt ctcttgtaac tctttaaaga cgggggattt ttgaccgata
    15781 taggggttaa tccagacgca gattttcagc cctttcgctt tcaggcggcg gatcatccct
    15841 tccgggtcag ggaaagtcag cgggtcccac tcaaaatcgc accactggaa ggctttcatc
    15901 cagaaacagt caaagtggaa aacatgcagc ggcagattgc gttccgccat accatcgata
    15961 aagctgttta ccgtcgcttc gtcgtagttg gtggtaaatg aagtgtttag ccacaggccg
    16021 aaggaccacg cgggcggcag cgccggacga ccagtaaagc gggtataacg atcaagtacc
    16081 gctttcggcg tcgggccgtc gataacaaag tattcgagat attcactctc aacgctgaac
    16141 tgcactttgg agactttctc cgatcccact tcaaaagaga cacactgggg atgattgacc
    16201 agtaccccat aaccacggtt agtcatgtag aacgggatat ttttatacgc ctgttcagta
    16261 cttgtgccgc cgtcccggtt ccaggtctct accgtctggc cattgcgcac cagggcagta
    16321 aagcgctctc ccagaccgta aactgtttcg ccaacgccaa gatcaagccg ctcaaacata
    16381 taattgcgtt gattattcgt gtcctgcacg tagccattat ttttcacctg actaccggta
    16441 atacgttcgc cgttgcgcag aaaatccagt gaccagaact cacctttgct gacacgcgcg
    16501 cttaagttgc cacttttaaa ctcagcataa cgttctgtgt tttcgattgt gaccttcacg
    16561 tcctgcaaaa tattgagcgg ataatgagga ccgttattca gcgccccctg aaaatgctca
    16621 atccgcacac cgacaatacc ttcctgtggg gagaaaaagc gcagcgtaaa taaaggcgta
    16681 tcaagctgcc aggtacgttc acgcacatca cggggggcag catagaccac catttcatta
    16741 tcctgctgtt caacctcgaa cacctgaagc gggtgaatca aattgaggcc aggttgaatc
    16801 aaccagtttc catcgctaat tttcattgcc gttccttagt tctgcacttc ttgagaggtg
    16861 aattgttgct ggcaacggcg tttaccctga gccagctgtt ccataacggt tttcagattg
    16921 tgcgtcgtga gtgagtagta gcgtttagcg ataatcgcgc tcagcaaata acagatcgcc
    16981 ggaacaatcg tgaatagcgc aataatgatg ctaatcgtgg cgctgttctg cgctttttct
    17041 gccgcatcat atccgccata agccagcatc cagccgataa gagcgccgcc gaaggccaac
    17101 cccagtttga gcacaaacag cgtgccagca aaactgatcc cggtcaggcg tttaccattg
    17161 caccactcgc cgtagtcgac ggtatcggac atcattaccc actggatagg tgtcaccagt
    17221 tgatgcaaca caccaatcac gaagatgaag acaaacatag tgatgctggc ctgcatggga
    17281 acaaagaaca tcgcgaggct aatcactgcc agcagggcgt tcgtccacca gaagatagtg
    17341 actttacatt tccagtcggt cagaggtttt gccagtgcgg aaccaatcag gttacccacg
    17401 caataagtgg tgagaaaagc gacaaacact tccggcgtgc ccaaaatcca tgtgacgtaa
    17461 tacatcatcg ccccaccgcg tacgcacacc gccaggatat tgaaaatggt tagtaaaccg
    17521 acaatccgcc actggtcgtt ttgccagata tcacgtaaat cttcccgcat agacgttgtt
    17581 gtaggtggtg cttcaacgcg ttctttagtg gtgaagaaac aaaatgccag catcatgaat
    17641 gccaccacgg aaaggaccgc gataccgccc tggaaaccga gtggtttatt atcaccgcca
    17701 attaaattaa ccagtggcat catcagaaca gtagaaagca tgcctcccgc ggtcgccagc
    17761 acaaaacgcc aggattgcag cgagatacgc tgagtcgggt cattggtgat tacaccaccc
    17821 aatgcgcagt aagggatatt gacgacggta taaagtaagg taagtagggt gtaagtaatt
    17881 gctgcataga tcattttgcc gttcatactg agatctggcg tgctataggc cagtacacag
    17941 acgatcccga atggcagtgc gccaaacagt acccacggac gaaatttacc ccagcgagag
    18001 cgcgttcgat cggccaacaa ccccatgcaa ggatcggaaa tcgcatccag tgcacgagcg
    18061 accaaaaaca tggttccgac aaaaccggca ggaatgccaa aaatatcggt ataaaagaac
    18121 atcatatata acattacgtt atcgaaaata atgtggctgg cggcgtctcc catgccataa
    18181 ccaattttct ctttaacgga caacacttca ctcttcatct gcttttcctt gatgctatag
    18241 gggtgctgag accgataacg cattttgtaa accatccctg tgagagcgaa tattccgata
    18301 tctggttatt aatttatgat tcttgtttta tgtgatcgtg gtagcgttaa ttccgctcat
    18361 atatcattgt aaaatatggg ttttatatga actataatgc tttcgtgata atacgctgcg
    18421 tgtattaggc ggaaaaaact gatctggggg atgtagaaac tcaaggaagt agctataatg
    18481 cgccccgcct ccatgtagca atcgaggcgc ggaagatcgt cgtctccggt gaggcggctg
    18541 gacttcaaat ccagttgggg ccgccagcgg tcccgggcag gttcgactcc tgtgatcttc
    18601 cgccaaaatg cctctcctga cgttctccaa ccccttgtaa tactgtcaat ccagatattt
    18661 tctactgctc aatattcaat cggcttcagg aatacctggt ctaaggtttt gtgatggacg
    18721 atgagcggct gaagaatccg cctgtcggtt cttctgtcct cgaacgcatc cgcgatattc
    18781 acgccagtat gcgccgtgtt tatttgcagg tgatttgccc ccctgctgac tctcagccaa
    18841 ctgtatcgcc attaaggtga agatgttgtt ttactcgccc cagaacaccc ttttttatac
    18901 gactattcta tttctttaac cgctggcgaa aaaaactgac tataaacttc accaataatc
    18961 agactgccat caagattaat ttgttcattt aatatatcaa atcaacttgt tttattttta
    19021 ctatcaaaaa tagctcattg ccttactata attaatatat aaattcggta attaattctt
    19081 aacatgcttt tactaataat ctcaattgct ggccctataa tattgcgcta gcattgcttt
    19141 ctggttgtat cagcgatact caaaaattct taatacaata ctcattcgac tggtacttat
    19201 ttgtaactca gttatatttt ttcgcccggt gattcagaag aatgcaaaaa acggctacca
    19261 ctccatcaaa aatacttgat ctcactgccg cggcattttt acttgtcgcc tttctgacga
    19321 gtattgcggg cgctcttcag actcctaccc taagtatatt cctcgcagat gaactgaaag
    19381 cccgtcctat aatggtaggt tttttcttca ccggtagcgc tattatggga attctggtca
    19441 gtcaatttct ggcaaggcac tccgataaac aaggcgaccg taaattactg attctgctat
    19501 gttgcttatt tggagtgctg gcctgcacgc tttttgcgtg gaatcgcaac tacttcattc
    19561 tcctctcaac gggcgtactt ctgagtagtt ttgcttccac cgcaaacccg caaatgttcg
    19621 ccctcgcccg tgaacacgcc gacagaacag gccgtgagac ggtcatgttc agtacatttt
    19681 tacgtgctca gatctcgctt gcctgggtta tcgggccacc gctcgcttat gaactggcaa
    19741 tgggatttag ttttaaagtg atgtatctca ccgctgccat cgcatttgtt gtttgcggac
    19801 tgatagtctg gttgtttttg ccatcaatac aaagaaatat tcctgtcgtt acccaacccg
    19861 tagaaatttt accctccacc cacaggaagc gggatacgcg gctacttttt gtggtctgtt
    19921 caatgatgtg ggcggcgaat aatctctaca tgataaatat gccgctattt attattgatg
    19981 aactgcatct aaccgataaa ctggctggag aaatgattgg tatcgctgcc ggtctggaaa
    20041 ttccgatgat gttaatcgca ggctattaca tgaaacgtat tggcaagcga ctattaatgc
    20101 tcattgctat cgtgagtgga atgtgttttt acgccagcgt actcatggcg acgactccgg
    20161 cggttgagct ggaattgcaa attcttaatg ccatcttcct tggtattctc tgtggtatcg
    20221 gcatgcttta ttttcaggac ttgatgcctg aaaaaatagg ctctgcgaca acgttatatg
    20281 caaatacttc acgcgtcggc tggattatcg ccggctctgt tgacggaatt atggttgaaa
    20341 tctggagcta ccatgcgttg ttctggctgg cgatagggat gttgggtatt gcgatgattt
    20401 gcctgctgtt tattaaagat atttagctca ccagtctggg ctaagaaaaa tcggcgtggc
    20461 gcaaacagag ccatcctcgc catttttgct atcatgcctg catacataaa cgacaaaaca
    20521 gtatgcagag ggaaaaatgg gttccaccag aaaggggatg ctgaacgttc tgattgccgc
    20581 cgtgttgtgg ggaagttcag gggtctgcgc gcaatacatc atggagcaaa gccagatgtc
    20641 gtcgcagttt ttgactatga cgcgtttgat attcgccggt ttgattctac tgacgctgtc
    20701 atttgttcat ggcgataaaa tcttttctat tattaacaat cataaagatg ccattagcct
    20761 gctgattttt tccgtggttg gcgcgctaac tgtacagctc acttttttgc taaccatcga
    20821 aaaatcgaac gcagccacgg caacggtgct gcaattcctc tcaccgacga ttatcgtcgc
    20881 ctggttctca ctggtgcgta aatcgcgccc gggcattctg gttttctgcg ctattttgac
    20941 atcgctggtc gggacttttt tattggtgac acacggtaat ccgacgtcat tatcgatctc
    21001 tcctgccgcg ttgttctggg gcattgcctc ggcatttgct gctgcattct ataccaccta
    21061 tccctcaacg ctaattgccc gctatggcac gttaccagtc gtcggctgga gtatgctgat
    21121 tggcggtctg attctgttgc ctttttatgc cagacaagga acaaactttg tcgttaacgg
    21181 cagtttgatt ctggcgtttt tttatttggt ggtcattggt acgtccctga catttagtct
    21241 gtacctgaaa ggagcacaat taattggcgg tccaaaagcc agcattttga gctgtgcaga
    21301 accattaagt agcgcgctac tctctttgct gttgctgggg atcacgttca cattaccgga
    21361 ctggctggga acgctgctga ttctgtcatc ggtgattttg atttcaatgg attcccgtcg
    21421 ccgcgccaga aaaataaatc gtccggcgcg gcataagtga gaattaccag ccaggcaccg
    21481 cgccaccgtt aaaaatggtt tctgccgctt tagcgacttc gggtgattga taagattgca
    21541 gaaattcctt cacgttttct gcattcttat tatcttcccg tgccaccaaa atattcacat
    21601 acggcgaatt cttatcttca ataaatacgc tgtcgtgcac cggagaaagc ccggtctgct
    21661 gaatgtaagt ggtgctgata atcgctacat caactttggg atcatccagt acgcgcggga
    21721 gctgcgcccc ctcgagttcc ataatctgca aatgacgagg attatcggtt atatccagcg
    21781 cggtaggtaa taaccctttt ccctctttca gagtaattag cttctctttt tgcaacagta
    21841 aaagtgcgcg accaaggttg gtcgggtcgt tggggatcgc cactgtcgcg ccttctttta
    21901 tttgcgccac ggttttgatt tttttggaat aacccgccat agggaagaca aacgtatttc
    21961 ccaccgctac cagtttataa ccatgcgcct gattatcttg ttcaagaaag ggtcgatgct
    22021 ggaagacatt cgcatcaagt tcgccatgat ttgtcgcatc gttcggtagc aacgaaccgc
    22081 taaatcctac cagttcaaca tcgaggccat atttctcttt tgccaccttt ttagcgactt
    22141 ccgcgacatc ttgttctgcg ccatttataa cgccaacttt aatgtgtttt gcatcgctgc
    22201 tactctggtc gcaacctgcc agcagaattc cggccagcaa taatgcggcc cctgtccgta
    22261 gatgatgtgt tgtcagtttc atttttttat ccttttatta atgattacct gactatagcg
    22321 gtaaggtcgc tgcggtttaa aaaacgaaac gctatcgata agaataaaaa ggaataaaag
    22381 tggaatataa agtctggcac ttcttactga ccacgcaagc gcgtttcgta cagcatgatg
    22441 agagcgatga aagcaaacta cacttatgct tcattcgata cacatttgta aaaggttgaa
    22501 tccatgaaac caacgacact actgcttatt ttcacttttt tcgctatgcc aggcatcgta
    22561 tacgccgagt cgccttttag ctcactgcag tccgcaaaag agaaaaccac ggtattacaa
    22621 gatttacgta aaatttgcac gccacaggcg tcattatcag atgaagcgtg ggaaaagtta
    22681 atgttgtcag atgaaaacaa taaacaacat atacgcgagg ccatcgtggc gatggaacgt
    22741 aataatcaga gcaattattg ggaagcgttg ggtaaggtag aatgcccgga tatgtaagaa
    22801 cagcaacaac tactgaccaa cgcttcttta cctgatatca ggatttcttc attttcacct
    22861 ttgcagtaac caacaatgca gtcagcaaca tcaatgtgcc ggacaacatc aacggcgaag
    22921 tcagaccaat attatccagc gcataaccgc cgattgccgc gccacaggta ttagcaagct
    22981 gaataaccgc cacctgaata gacccggctt tttctgcctg atcggccagc gagcgggtga
    23041 tccacgttga ccagccgacg ggaaccaatg caaaagttag cccccagata atcgccacgc
    23101 cggtagcaac gattttatcg cttccccaca acgtcagtac caacgcactc acagccagta
    23161 ttaacggcgc gcctgctaag gccagtttta ccgaacgttt aagaatgaac gacgaaagcg
    23221 acgtaccaat aaagctggcg ataccaaaac tcaacagcac cagcgttaag ccatccacgc
    23281 cgaatcccgc caggttcata tacaccgggc gaatatacgt gaagaaagca aactgcccgg
    23341 cgaaagacat gaagatggcg atcatccctg ccatcacacc cggacgttgt aataagcgga
    23401 aagtattttg tttctgatgc gagggttcgc ctggcagtga aggcaatgat ttgataatcc
    23461 agaaaataca cagcacgccc atcaccgccg ccgcattaaa gacattgcgc caaccgataa
    23521 gctcgcctaa aaaactgccc aacggcgcgg caatcaccag cgcaatagaa accgcgccga
    23581 agatcaccga cagcgccttc ggcaccgtac gcggcggcac cagacgcatg gtcagcgacg
    23641 ccgacatcgc ccagaacccg cccagcgcca gccccagaca ggcacgaccg attaaaagca
    23701 aactgaatga gttagcaaag gaaaccagca agcaggagag cgtcagcaaa acggcaaaca
    23761 aaataacaac gtagcggcgg tcagtagcct gaattgtctg ggtaataaac aaactggcaa
    23821 acattgccac aaaggcggtc acggtcaccg attgcccggc aaccccttcc gaaatgccta
    23881 aatcctgggc cattggcgtc aacaaactga cgggcaaaaa ctcaacgata atcagacagg
    23941 cgacacaaaa cgccaccgag aaaacggctg accagttcgg tcgggtgatg gcatccgcgc
    24001 cgcggttttc ggcaataaat tcactcatgg tgttacccgt ggcatgtttc aggggaaaag
    24061 ccgaccactt taacattgaa atgtgtgacg catttaacgt ttttgcaact tttacggtgt
    24121 tgcttgagct ggagttaaga tcgaaacgga acagggcaaa gattaccgga tgcggcgtga
    24181 acgtcttatc cacccgacag gtcaggcgcg gtctgtaggc tgataagacg aaacggtttc
    24241 aatgcaacca gtgaacgccc tcggcaggct gaaagaacgc gttatagcgc atctgaaaag
    24301 cattaatatc ctgcatttca ggttcggttt cgcgcagaaa acctagcgcc agcctgacct
    24361 gagcgtcggt aatcggcgcg gcgaggcgag ctttttgtaa aatccgatgc cattgcagca
    24421 ggttctgttc gctaccatcg acaatgacaa tttgccagat gagcaacacc tgcgcggcgt
    24481 tttgcaggtg cgactcatcc ggacgatgca aataacgtaa aaattcgtca ccagctgact
    24541 ttcccatttg atcgaccatc gactccacgg gtacgacatc gatgttcagc cgatcgctga
    24601 gacggcgaat cgcttttctg gccccggatg tcagcacccg aaaaccaacc acaaacacta
    24661 ccgccagcgt ggcgagcatt atccagatca tgagttctcc tgcgtaatca gaactcatga
    24721 tatctggaaa ccctcgccag ttactaatcc accagaataa tcttcagtgc aaacagagct
    24781 gcgaccacca ccacacacag gttcagatcg cgccagcgcc cggtgcatac tttcatgatg
    24841 cagtacgaca taaagccgag tgcaatccct tcggtgatcg agaaagtaaa gggcatcatc
    24901 accgtggtaa taaacgcagg caccgattcg gtaaaatcat cccagttaac gcgcgccagg
    24961 ctcgaagtca tcagcacgcc aacaaagatt aacgctccgg cggttgcgta aggaggaact
    25021 atcgccacca gcggtgagaa gaacataacc aacaggaaca taacgccaac cacaaccgca
    25081 gtcagccccg tgcggccacc gactgccaca ccagaagtac tttcaatata ggcagtaaca
    25141 gacgaggtgc cgataaacgc acccgccacc gaactgacgc tatcaacata cagcgcctta
    25201 ttcatattgg ggaatttacc gttaccatct attaagcccg ctttatcagt tacaccaatt
    25261 aatgttcctg atgaatcaaa taggttgatc agcataaagg agaaaatgat accggcgagt
    25321 tcaagtgtta acgcgccgct caaatctact tcaccaatga cgccgctaat atcaggcgga
    25381 atggaataga cgccgctaaa atgaacatca ccgaaaaata atccacagca agacgtcacc
    25441 acaatagaaa ccagcaccgc ggcatgaaaa tgacgtgatg acaacacggt tataataaaa
    25501 aaccctaaaa tacctaacaa cacgccgtga gaacttaaat cgccaatcat caccagcgtg
    25561 tctttattgg cgacaataac gccagtattt tttaatccca ttaaggcgat aaataatcca
    25621 attccgctgg tgataccaat acgtaaactt aagggaatgt tggagatcat ccagtaccgg
    25681 atacgaaaca gcgtgagcaa aaatagtcca actgcgcccc agaatattgc gcccatcccg
    25741 gtctgccagg agatgcccat cgcccccacg accacgaagg caaagaaggc gttcagcccc
    25801 attgccggag ccagcgccac gggtaagtta gcaaatatcc ccatcgcaat actgccgata
    25861 ccggcaatca aacaggtggt aacaaacacc actttcgggt ccatttgtgc cgcgccgagg
    25921 atttgcgggt tcacaaaaac gatgtacacc atggttaaaa aagtggtcat ccccgcaatc
    25981 aattctgtgc ggacggtggt cccatgctga ggtagtttaa ataatcgcga aagcgtccct
    26041 gattcattac tcacgtaatc ggtattgtca ttattcattt ttttgtccat tggaggagat
    26101 ttaatccctt gcttttgtaa aacaaatgac aacaacggtt cagtgataat tatcacattt
    26161 caat
//
LOCUS       DACAOP010000061        25907 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.061, whole genome shotgun sequence.
ACCESSION   DACAOP010000061 DACAOP010000000
VERSION     DACAOP010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25907
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.061"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            37..1338
                     /gene="rstB"
                     /locus_tag="IT892_002824"
     CDS             37..1338
                     /gene="rstB"
                     /locus_tag="IT892_002824"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RstB"
                     /protein_id="HAP3136021.1"
                     /translation="MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMN
                     SSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVEPLSKYHLDDISMHRLRGGEIVA
                     LDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPH
                     WQDMLKLEAAAQRFGDGHLNERIHFDEGSSFERLGVAFNQMADNINALIASKKQLIDG
                     IAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELH
                     LSEPDLPLWLSTHLADIQAVTPDKTVRIKTLVQGHYAALDMRLMERVLDNLLNNALRY
                     CHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLA
                     IVHSIALAMGGTVNCDTSELGGARFSFSWPLWHNIPQFTSA"
     gene            1414..2343
                     /gene="tus"
                     /locus_tag="IT892_002825"
     CDS             1414..2343
                     /gene="tus"
                     /locus_tag="IT892_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication terminus site-binding protein"
                     /protein_id="HAP3136022.1"
                     /translation="MARYDLVDRLNTTFRQMEQELAIFAAHLEQHKLLVARVFSLPEV
                     KKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQV
                     DNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLT
                     VLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQD
                     IAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGE
                     LLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD"
     gene            complement(2340..3743)
                     /gene="fumC"
                     /locus_tag="IT892_002826"
     CDS             complement(2340..3743)
                     /gene="fumC"
                     /locus_tag="IT892_002826"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HAP3136023.1"
                     /translation="MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSL
                     IHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQS
                     NMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQL
                     IPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYS
                     LPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQ
                     AHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALT
                     MLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIE
                     PNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEF
                     DSWVRPEQMVGSMKAGR"
     gene            complement(3886..5532)
                     /locus_tag="IT892_002827"
     CDS             complement(3886..5532)
                     /locus_tag="IT892_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HAP3136024.1"
                     /translation="MSNKPFHYQAPFPLKKDDTEYYLLTSEHVSVSEFEGQEILKVAP
                     EALTLLARQAFHDASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAKYYDELPTEGNEHGQAFRDVELEKEL
                     LIEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIW
                     IEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVG
                     RDIAHAKLKERMDNGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQ
                     LQAQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIQLTQCTRCVK"
     gene            5731..6906
                     /gene="manA"
                     /locus_tag="IT892_002828"
     CDS             5731..6906
                     /gene="manA"
                     /locus_tag="IT892_002828"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416130.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HAP3136025.1"
                     /translation="MQKLINSVQNYAWGSKTALTELYGMENPSSQPMAELWMGAHPKS
                     SSRVQNAAGDIVSLRDVIESDKSTLLGEAVAKRFGELPFLFKVLCAAQPLSIQVHPNK
                     HNSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALTPFLAMNAFREFSEIVSLLQP
                     VAGAHPAIAHFLQQPDAERLSELFASLLNMQGEEKSRALAILKSALDSQQGEPWQTIR
                     LISEFYPEDSGLFSPLLLNVVKLNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAG
                     LTPKYIDIPELVANVKFEAKPANQLLTQPVKQGAELDFPIPVDDFAFSLHDLSDKETT
                     ISQQSAAILFCVEGDATLWKGSQQLQLKPGESAFIAANESPVTVKGHGRLARVYNKL"
     gene            7007..8515
                     /locus_tag="IT892_002829"
     CDS             7007..8515
                     /locus_tag="IT892_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HAP3136026.1"
                     /translation="MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQL
                     KLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKENPWIKSGQSVIFNESVDHGPFP
                     LAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLK
                     PLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAQSGRIDAVNEYNQKVQLTFNNLK
                     TDGSSTLASFGERVGNQKLSLEKMTISVEGKELALLEGMEISGKSDLVNDGKTINSQL
                     DYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQALLAQPEIANNPELY
                     QEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLA
                     QEVDRSVKSLDAKLTIPVDMATEFMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFR
                     LTTLQDNTITTSLQYANGQITLNGQKMSLEDFVGMFAMPALNVPAVPAIPQQ"
     gene            complement(8741..10006)
                     /gene="uidC"
                     /locus_tag="IT892_002830"
     CDS             complement(8741..10006)
                     /gene="uidC"
                     /locus_tag="IT892_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416132.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide uptake porin UidC"
                     /protein_id="HAP3136027.1"
                     /translation="MRKIVAMAVICLTAASGLTSAYAAQLADDEAGLRIRLKNELRRA
                     DKPSAGAGRDFYAWVQGGLLDFNSGYYSNIIGVEGGAYYVYKLGARADMSTRWYLDGD
                     KSFGFALGAVKIKPSENSLLKLGRFGTDYSYGSLPYRIPLMAGSSQRTLPTVSEGALG
                     YWALTPNIDLWGMWRSRVFLWTDSTTGIRDEGVYNSQTGKYDKHRARSFLAASWHDDT
                     SRYSLGASVQKDVSNQIQSILEKSIPLDPNYTLKGELLGFYAQLEGLSRNTSQPNETA
                     LVSGQLTWNAPWGSVFGSGGYLRHAMNGAVVDTDIGYPFSLSLDRNREGMQSWQLGVN
                     YRLTPQFTLTFAPIVTRGYESSKRDVRIEGTGILGGMNYRVSEGPLQGMNFFLAADKG
                     REKRDGSTLGDRLNYWDVKMSIQYDFMLK"
     gene            complement(10045..11418)
                     /gene="uidB"
                     /locus_tag="IT892_002831"
     CDS             complement(10045..11418)
                     /gene="uidB"
                     /locus_tag="IT892_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide transporter"
                     /protein_id="HAP3136028.1"
                     /translation="MNQQLSWRTIVGYSLGDVANNFAFAMGALFLLSYYTDVAGVGAA
                     AAGTMLLLVRVFDAFADVFAGRVVDSVNTRWGKFRPFLLFGTAPLMIFSVLVFWVPTD
                     WSHGSKVVYAYLTYMGLGLCYSLVNIPYGSLATAMTQQPQSRARLGAARGIAASLTFV
                     CLAFLIGPSIKNSSPEEMVSVYHFWTIVLAIAGMVLYFICFKSTRENVVRIVAQPSLN
                     ISLQTLKRNRPLFMLCIGALCVLISTFAVSASSLFYVRYVLNDTGLFTVLVLVQNLVG
                     TVASAPLVPGMVARIGKKNTFLIGALLGTCGYLLFFWVSVWSLPVALVALAIASIGQG
                     VTMTVMWALEADTVEYGEYLTGVRIEGLTYSLFSFTRKCGQAIGGSIPAFILGLSGYI
                     ANQVQTPEVIMGIRTSIALVPCGFMLLAFVIIWFYPLTDKKFKEIVVEIDNRKKVQQQ
                     LISDITN"
     gene            complement(11415..13226)
                     /gene="uidA"
                     /locus_tag="IT892_002832"
     CDS             complement(11415..13226)
                     /gene="uidA"
                     /locus_tag="IT892_002832"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAP3136029.1"
                     /translation="MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRA
                     IAVPGSFNDQFADADIRNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQ
                     EVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSY
                     FHDFFNYAGIHRSVMLYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRD
                     ADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAV
                     KGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYA
                     EEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAI
                     KELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCD
                     AHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVD
                     TLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGN
                     KKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ"
     gene            complement(13617..14207)
                     /locus_tag="IT892_002833"
     CDS             complement(13617..14207)
                     /locus_tag="IT892_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP3136030.1"
                     /translation="MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAIS
                     PGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQR
                     ALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLL
                     DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS"
     gene            complement(14428..15195)
                     /gene="hdhA"
                     /locus_tag="IT892_002834"
     CDS             complement(14428..15195)
                     /gene="hdhA"
                     /locus_tag="IT892_002834"
                     /EC_number="1.1.1.159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-alpha-hydroxysteroid dehydrogenase"
                     /protein_id="HAP3136031.1"
                     /translation="MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN
                     ADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPK
                     PFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYA
                     SSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRL
                     GQPQDIANAALFLCSPAASWVSGQILTVSGGGVQELN"
     gene            complement(15307..16335)
                     /locus_tag="IT892_002835"
     CDS             complement(15307..16335)
                     /locus_tag="IT892_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mal regulon transcriptional regulator MalI"
                     /protein_id="HAP3136032.1"
                     /translation="MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTATGERVNAA
                     IEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYAELTAGLTEALEAQGRMVFLLHG
                     GKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRMAEEKAIPVIFASRASYLDDVD
                     TVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSD
                     WVLECTSSQKQAAEAITALLRHNPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDR
                     YFEQQVSLAAFTDATPTTLDDIPVTWASTPARELGITLADRMMQKITHEETHSRNLII
                     PARLIAAK"
     gene            16510..18102
                     /locus_tag="IT892_002836"
     CDS             16510..18102
                     /locus_tag="IT892_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IICB"
                     /protein_id="HAP3136033.1"
                     /translation="MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSS
                     HDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGF
                     IGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWM
                     LHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINS
                     AGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSC
                     PTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVV
                     GGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHG
                     LSTKWYMVPVVAAIWFVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGY
                     NVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQV
                     VIGPQVQSVKDEMAGLMHTVQA"
     gene            18112..19284
                     /gene="malY"
                     /locus_tag="IT892_002837"
     CDS             18112..19284
                     /gene="malY"
                     /locus_tag="IT892_002837"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional maltose regulon transcriptional
                     repressor/cystathionine beta-lyase MalY"
                     /protein_id="HAP3136034.1"
                     /translation="MFDFSKVVDRHGTWCTQWDYVADRFGTADLLPFTISDMDFATAP
                     CIIEALNQRLMHGVFGYSRWKNDEFLAAIAHWFSTQHYTAIDSQTVVYGPSVIYMVSE
                     LIRQWSETGEGVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADGWFCDMGKLEAVLAK
                     PECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWS
                     NVARGDWALLTSGSKSFNIPALTGAYGIIENSSSRDAYLSALKGRDGLSSPSVLALTA
                     HIAAYQQGAPWLDALRIYLKDNLTYIADKMNAAFPELNWQIPQSTYLAWLDLRPLNID
                     DNALQKALIEQEKVAIMPGYTYGEEGRGFVRLNAGCPRSKLEKGVAGLINAIRAVR"
     gene            19388..20389
                     /gene="add"
                     /locus_tag="IT892_002838"
     CDS             19388..20389
                     /gene="add"
                     /locus_tag="IT892_002838"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAP3136035.1"
                     /translation="MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLI
                     PHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARHGLHYVELRFSPG
                     YMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
                     DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER
                     IGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASIN
                     TDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK"
     gene            complement(20423..21469)
                     /locus_tag="IT892_002839"
     CDS             complement(20423..21469)
                     /locus_tag="IT892_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310359.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP3136036.1"
                     /translation="MSDNIRVGLIGYGYASKTFHAPLIAGTPGLELAVISSSDETKVK
                     ADWPTVTVVSEPKHLFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLS
                     QARELDALAKSLGRVLSVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVR
                     DRWREQGGPGSGIWYDLAPHLLDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSY
                     PQRRVILHGTMLAAAESARYIVHGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRD
                     GVLTRVEGEERVEETLLTVPVPGNYPAYYAAIRDALNGDGENPVPASQAIQVMELIEL
                     GIESAKHRATLCLA"
     gene            21712..21837
                     /gene="blr"
                     /locus_tag="IT892_002840"
     CDS             21712..21837
                     /gene="blr"
                     /locus_tag="IT892_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division septum protein Blr"
                     /protein_id="HAP3136037.1"
                     /translation="MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK"
     gene            22110..22325
                     /gene="ydgT"
                     /locus_tag="IT892_002841"
     CDS             22110..22325
                     /gene="ydgT"
                     /locus_tag="IT892_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription modulator YdgT"
                     /protein_id="HAP3136038.1"
                     /translation="MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAAD
                     HRRAELVSGGRLFDLGQVPKSVWHYVQ"
     gene            22411..22851
                     /locus_tag="IT892_002842"
     CDS             22411..22851
                     /locus_tag="IT892_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HAP3136039.1"
                     /translation="MTTTTPQRIGGWLLGPLAWLLVALLSTTLALLLYTAALSSPQTF
                     QTLGGQALTTQILWGVSFITAIALWYYTLWLTIAFFKRRRCVPKHYIIWLLISVLLAV
                     KAFAFSPVEDGIAVRQLLFTLLATALIVPYFKRSSRVKATFVNP"
     gene            22928..23509
                     /gene="rsxA"
                     /locus_tag="IT892_002843"
     CDS             22928..23509
                     /gene="rsxA"
                     /locus_tag="IT892_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017456621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HAP3136040.1"
                     /translation="MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLA
                     TTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRL
                     LGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
                     ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL"
     gene            23509..24087
                     /gene="rsxB"
                     /locus_tag="IT892_002844"
     CDS             23509..24087
                     /gene="rsxB"
                     /locus_tag="IT892_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HAP3136041.1"
                     /translation="MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEIL
                     PQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQE
                     ITPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
                     CISLQPVAETPDSWKWDLNTIPVRIIPVEHHA"
     gene            24080..>25907
                     /gene="rsxC"
                     /locus_tag="IT892_002845"
     CDS             24080..>25907
                     /gene="rsxC"
                     /locus_tag="IT892_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HAP3136042.1"
                     /translation="MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFV
                     IPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSA
                     LAELSVIIDADGEDCWIPRDGWADYRTRSREELIERIHQFGVAGLGGAGFPTGVKLQG
                     GGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKP
                     QAISMLRAVLADSNDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNV
                     GTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQM
                     VIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLL
                     PQQLFWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEE
                     KRAAEAKARFEARQARLEREKAARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQAT
                     QPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVADPRKTAVEAAIARA
                     KARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQAN"
BASE COUNT         6282 a         6734 c         6344 g         6547 t
ORIGIN      
        1 ggctatcttt ttgcgcctca tgcatgggaa taagcgatga aaaaactgtt tatccagttt
       61 tacctgttat tgtttgtctg cttccttgtg atgtctctgc tggttgggct ggtgtacaaa
      121 tttaccgccg aacgcgcggg caaacagtcg ctggatgatt tgatgaacag ttcgctgtat
      181 ctgatgcgca gcgaattgcg tgagatcccc ccacacgact ggggtaaaac tctgaaagag
      241 atggatttaa atctctcttt cgatctgcgt gtcgagccac tgagtaaata ccatcttgat
      301 gatatttcca tgcaccgact gcgtggcggc gaaattgtcg ccctggacga tcagtacacg
      361 tttttgcagc gtatcccgcg cagccactac gtgctggcag ttggtcctgt tccttatctt
      421 tattatctcc atcagatgcg attgctggat atcgccctga tcgcttttat tgctatttcc
      481 ctcgcctttc cggtgtttat ctggatgcgt ccgcactggc aggatatgtt aaaactggaa
      541 gcagcggcgc aacgatttgg cgatgggcat ctcaatgaac gtatccactt tgatgagggt
      601 tcgagctttg aacgacttgg cgtcgcattt aaccagatgg cggacaatat caacgcctta
      661 attgccagca aaaaacagct tattgacggt atcgctcacg aactgcgaac accgttagtg
      721 cgcctgcgtt atcgactgga gatgagcgat aacctgagcg ccgccgaatc ccaggcgttg
      781 aatcgtgata tcagtcaact tgaagcttta attgaagagc tgctgactta tgcccgactc
      841 gatcgcccac aaaacgagct tcatcttagc gaaccagacc tgccgttgtg gctgtcaacg
      901 catctggcag atattcaggc agtaacgccc gataaaacgg tacggataaa aacgctcgtg
      961 caaggccatt atgcggcgtt ggatatgcgc ttaatggagc gcgtgctgga taatttgctc
     1021 aataacgccc tgcggtactg ccattcaacg gttgaaacca gcctgctact gtcggggaat
     1081 agagcgacat taattgttga ggatgatggc ccagggattg ccccagaaaa ccgcgaacat
     1141 atctttgaac cttttgttcg cctcgatccc agccgggatc gctcaaccgg cggctgcggg
     1201 ctggggctgg caattgtcca ctctatagca ctggcaatgg gcggtacggt taattgtgac
     1261 accagcgaac tgggtggtgc ccgcttctcg tttagctggc cgttatggca taacatcccg
     1321 caatttacct ctgcctgaca ctacgcgcac gatggtcaag tcaccacgac tgtgctataa
     1381 aataagtatg ttgtaactaa agtggttaat attatggcgc gttacgatct cgtagaccga
     1441 ctcaacacta cctttcgcca gatggaacaa gagctggcta tatttgccgc tcatcttgag
     1501 caacacaagc tattggttgc ccgcgtgttc tctttgccgg aggtaaaaaa agaggatgag
     1561 cataatccgc ttaatcgtat tgaggtaaaa caacatctcg gcaacgacgc gcagtcgctg
     1621 gcgttgcgtc atttccgcca tttatttatt caacaacagt ccgaaaatcg cagcagcaag
     1681 gccgctgtcc gtctgcctgg cgtgttgtgt taccaggtcg ataacctttc gcaagcagcg
     1741 ttggtcagtc atattcagca catcaataaa ctcaagacca cgttcgagca tatcgtcacg
     1801 gttgaatcag aactccccac cgcggcacgt tttgaatggg tgcatcgtca tttgccgggg
     1861 ctgatcaccc ttaatgctta ccgcacgctc accgttctgc acgaccccgc cactttacgc
     1921 tttggttggg ctaataaaca tatcattaag aatttacatc gtgatgaagt cctggcacag
     1981 ctggaaaaaa gcctgaaatc accacgcagt gtcgcaccgt ggacgcgcga ggagtggcaa
     2041 agaaaactgg agcgagagta tcaggatatc gctgccctgc cacagaacgc gaagttaaaa
     2101 atcaaacgtc cggtgaaggt gcagccgatt gcccgcgtct ggtacaaagg agatcaaaaa
     2161 caagtccaac acgcctgccc tacaccactg attgcactga ttaatcggga taatggcgcg
     2221 ggcgtgccgg acgttggtga gttgttaaat tacgatgccg acaatgtgca gcaccgttat
     2281 aaacctcagg cgcagccgct tcgtttgatc attccacggc tgcacctgta tgttgcagat
     2341 taacgcccgg ctttcatact gccgaccatc tgttctggcc gtacccagct gtcaaactcg
     2401 gcttcgctaa gataccccag cgcaagggcc gcagctttta aggtcagccc ttctttatgc
     2461 gcttttttgg cgatctcggc ggctttgtca taaccaatgt gggtgttaag cgcagtcacc
     2521 agcatcagcg attcattgag taattgattg attcgctcac gattcggttc aatacccact
     2581 gcgcagtgtt tgttaaaact ttccatgcca tctgccagca agcgcaccga ttgcaggaaa
     2641 ttgtggatca ccattggacg gaagacgttc agttcaaagt taccggaagc gccccccatg
     2701 ttgatcgcca cgtcgttccc catcacctga cagcagagca tggttaatgc ctcacactgt
     2761 gttgggttca ctttccccgg catgattgag ctgcccggct cattttccgg gattgagatt
     2821 tcaccaattc cgcagcgcgg gccagaggcc agccagcgga catcattggc gattttcatc
     2881 agtgacgcag ccaacccttt caacgcgccg tgcgcctgaa ccagggcatc acaggtcgcc
     2941 agcgcttcaa atttgttcgg cgcggtaaca aacggtgcac aggtaatgac tgccagttca
     3001 tctgctacgc gacgcgcata ctccggatgg gtatttagtc cagtacccac cgctgtaccg
     3061 ccaagagcca gttccgctac gtgaggcagg ctgtattcga tatgtttgag attatgctcg
     3121 agcatcgcta cccagccgga aatctcctgc cccagcgtta acggcgtggc atcctgcaag
     3181 tgagtacgac caattttgac gatatcggca aaagcacggg atttctcatt cagtgtctgt
     3241 gtcagggttt taagctgagg aatgagttgc ttgcgcagcg ccagcagcgc cgcaacgtgc
     3301 atcgccgtcg gaaagacatc gttggaactt tggcttttgt tcacgtcgtc gttagggtga
     3361 actttacgtt ccatcccgcg cacaccgccg agtaattcac tggcccggtt agccagcact
     3421 tcgttcatgt tcatgttact ttgcgtgccg gagccggtct gccagatagc cagcgggaat
     3481 tcgtcgtcat gctgtcctgc cagtacttca tccgccgcct gacgaatggc gctcgctttc
     3541 tcttcagaca acaagcctaa atcttcatta acttttgccg ctgcacgctt ggttagcgcc
     3601 agcgcatgaa tcagtgaggt gggcattttc tccgtcgaaa tgcggaaatg ctccagcgag
     3661 cgttgagttt gtgcgcccca cagcttatct gccgggacat caatcgcccc catcgaatct
     3721 ttttcgctgc gtactgtatt catgacctgc tcctcacctg attaattttt tctttctgtt
     3781 ttgctttcgt taagcaactt ttagctcact tattatttac catttgataa caaatgtttg
     3841 gtctttcgtg ccatgtaaaa aaaccgcccc gaagggcggc tctgtttatt tcacacagcg
     3901 ggtgcattgt gtgagttgta tctgctggaa gaagtcattt cctttatcat ccacaaggat
     3961 aaacgccggg aaatcttcca cttcaatttt ccagatggct tccattccca gttccggata
     4021 ttcaacacat tccaggctct taatacttcc ctgcgccaat acagcggccg gaccaccgat
     4081 actgccaagg tagaagccgc cgtgtttttt acaggcatcc gtcacctgct ggctgcggtt
     4141 gcctttcgcc agcatgatca tacttccgcc ctgcgcttgc agttgatcga cataagaatc
     4201 catccgtccg gcggtcgttg ggccaagaga accggaggca taaccttccg gcgttttggc
     4261 cggacccgcg tagtaaatcg gatgatcttt gatgtactgc ggcagccctt caccgttatc
     4321 catccgctct ttcagtttgg cgtgagcaat atcacgaccg acgataatcg tgccgttaag
     4381 cgataagcgt gtagaaacgg gatactgcga caactgtgcg aggatctctt tcatcggacg
     4441 gttaaggtca acgcgcaccg cttcgccttc tcccgctttg cgcagctctt ccgggatata
     4501 tttgcctgga ttatgttcca gtttttcgat ccagatcccc tgacggttga tcttcgcttt
     4561 gatattacgg tcagcagagc aggagacgcc cataccgacc gggcaggatg cgccgtgacg
     4621 tggcaggcga atcacgcgga tgtcgtgagc gaagtattta ccaccaaact gcgcacccag
     4681 accaagattt tgcgcttcga tcagcaattc tttttccagt tccacatcgc ggaacgcctg
     4741 accgtgctca ttcccttccg ttggcagttc atcatagtat ttcgcggaag ccagtttcac
     4801 cgttttaagg ttcgtttctg cagaagttcc accaataacg aacgcaatat gatacggagg
     4861 acaggccgcc gtacccagcg tgcgcatctt ctcaaccagg taatttttca gtttccccgg
     4921 cgtcagtaac gctttggttt cctgatagag atacgtcttg tttgccgaac caccaccttt
     4981 ggcgatacag aggaatttgt attcgtcgcc atcaacggca taaagatcga tctgcgctgg
     5041 cagattggtg ccggtattca cttctttata catatccagc ggcgcgtttt gcgagtagcg
     5101 cagattatct tcgatataag tgttatagac accgcgcgcc agcgccgctt catcaccacc
     5161 accggtccat acacgctgcc cttttttacc aacaataatc gcggtgccgg tatcctgaca
     5221 ggttggcaga acgcctttcg ccgcgatgtc ggagttacgc aggaattgca gcgccacata
     5281 tttatcattt tcgctggcct ccgggtcacg cagaatgtcg gccacctgtt gttggtgcgc
     5341 cggacgcagc atgaacgacg catcatgaaa cgcctggcgc gccaacagag ttaacgcttc
     5401 gggtgcgact ttcaaaatct cctgcccttc aaattcagat acgctaacgt gttcgctggt
     5461 tagcaggtaa tactcagtat catctttttt gagtggaaaa ggagcctgat aatgaaaggg
     5521 tttgtttgac attgttctct cacttactgc ctggtttggt tatgctctgg gcgggtgttc
     5581 cgttgccctg ttaaaagcga gtaacaatat cctacacact tttttaacaa aaactgagac
     5641 tagtacgact ttttgcggct ccaggttact tcccgtagga ttcttgcttt aatagtggga
     5701 ttaatttcca cattaaaaca gggattgatc atgcaaaaac tcattaactc agtgcaaaac
     5761 tatgcctggg gcagcaaaac ggcgttgact gaactttatg gtatggaaaa tccgtccagc
     5821 cagccgatgg ccgagctgtg gatgggcgca catccgaaaa gcagttcacg agtgcagaat
     5881 gccgccggag atatcgtttc actgcgtgat gtgattgaga gtgataaatc gactctgctc
     5941 ggagaggccg ttgccaaacg ctttggcgaa ctgcctttcc tgttcaaagt attatgcgca
     6001 gcacagccac tctccattca ggttcatcca aacaaacaca attctgaaat cggttttgcc
     6061 aaagaaaatg ccgcaggtat cccgatggat gccgccgagc gtaactataa agatcctaac
     6121 cacaagccgg agctggtttt tgcgctgacg cctttccttg cgatgaacgc gtttcgtgaa
     6181 ttttccgaga ttgtctccct actccagccg gtcgcaggtg cacatccggc gattgctcac
     6241 tttttacaac agcctgatgc cgaacgttta agcgaactgt tcgccagcct gttgaatatg
     6301 cagggtgaag aaaaatcccg cgcgctggcg attttaaaat cggccctcga tagccagcag
     6361 ggtgaaccgt ggcaaacgat tcgtttaatt tctgaatttt acccggaaga cagcggtctg
     6421 ttctccccgc tattgctgaa tgtggtgaaa ttgaaccctg gcgaagcgat gttcctgttc
     6481 gctgaaacac cgcacgctta cctgcaaggc gtggcgctgg aagtgatggc aaactccgat
     6541 aacgtgctgc gtgcgggtct gacgcctaaa tacattgata ttccggaact ggttgccaat
     6601 gtgaaattcg aagccaaacc ggctaaccag ttgttgaccc agccggtgaa acaaggtgca
     6661 gaactggact tcccgattcc agtggatgat tttgccttct cgctgcatga ccttagtgat
     6721 aaagaaacca ccattagcca gcagagtgcc gccattttgt tctgcgtcga aggcgatgca
     6781 acgttgtgga aaggttctca gcagttacag cttaaaccgg gtgaatcagc gtttattgcc
     6841 gccaacgaat caccggtgac tgtcaaaggc cacggccgtt tagcgcgtgt ttacaacaag
     6901 ctgtaagagc ttactgaaaa aattaacatc tcttgctaag cttattaaag gcttataaca
     6961 ccttcaggcg gccagtccgc ctgatttcat tttatggata atcattatga ataaatcgct
     7021 ggtagcggta ggcgtcattg ttgcgctagg cgtagtctgg acaggcggcg catggtatac
     7081 aggcaagaag attgaaaccc atctcgaaga catggtcgcg caggcgaacg cgcaactcaa
     7141 actgacagct cctgaatcca acctggaagt gagttatcaa aactatcatc gcggcgtatt
     7201 cagcagccag ttgcaactgt tggtgaaacc cattgccggg aaagaaaatc cgtggattaa
     7261 aagcggtcag agcgtcatct tcaacgaatc ggttgatcat ggtcccttcc cgcttgccca
     7321 gcttaaaaaa ctgaacctga tcccgtcgat ggcatcaatt caaaccacgc tggttaataa
     7381 cgaagtaagc aaaccactgt ttgatatggc aaaaggtgaa acgccttttg agattaactc
     7441 gcgcattggt tacagcggtg attccagttc cgatatttcg ctcaagccac tgaattacga
     7501 gcaaaaagat gaaaaagtcg cctttagcgg cggcgagttc cagttaaatg ctgacagaga
     7561 cggcaaagcc atctcccttt ccggggaggc gcaaagtggt cggatagacg cagttaacga
     7621 atacaaccag aaagtgcagt tgacctttaa taatctgaaa accgacggtt ccagcacgct
     7681 ggcaagtttt ggtgagcgtg taggaaatca aaaactgtca ctggaaaaaa tgaccatttc
     7741 agtggaaggc aaagaactgg cactgctgga aggcatggag atcagcggta aatcggatct
     7801 ggtcaatgac ggtaaaacga tcaatagcca actggattac tcgctaaaca gcctgaaggt
     7861 acagaatcag gatctgggca gcggcaagct gactttaaaa gtcggccaga ttgatggtga
     7921 agcctggcat cagtttagcc agcaatataa cgcgcaaact caggcgctgc tggcacagcc
     7981 agaaattgcc aacaaccccg aactttatca ggagaaagtg acggaagcct tctttagcgc
     8041 cctgccgctg atgctgaaag gcgatccggt gattactatc gcgccgctaa gctggaaaaa
     8101 cagtcagggt gaaagtgccc tgaatctgtc gctgttcctg aaagatccgg caacgactaa
     8161 agaagcgccg caaacgctgg cgcaggaagt agatcgttcg gttaaatctc tggatgcgaa
     8221 actgaccatt ccggtggata tggcaactga gtttatgact caggtagcga agctggaagg
     8281 ttatcaggaa gatcaagcga aaaaactggc gaaacagcaa gttgaaggtg catcagcaat
     8341 ggggcagatg ttccgtctga ccaccttgca ggacaatacc atcaccacca gcctgcaata
     8401 tgctaacggt cagataacgt taaatgggca gaaaatgtcg ttagaagatt ttgttggcat
     8461 gtttgcgatg ccagctctta acgttccggc tgtaccggca attccgcagc agtaattcac
     8521 ggccaaaacg ccggagaatt ttcactccgg cgttttcatc tgaaaacaaa ccagagattg
     8581 cctgatgcgc tacgcttatc aggcctacct tttcctgcaa cactttgaat ttatgagttt
     8641 ttgtaggctg gataaggcgt ttacgccgca tccggcataa aaaacgcgca ctttgtcaac
     8701 aatctgaaac gccggagatt tttctctccg gcgttatttt ttacttcagc ataaagtcat
     8761 actgaatact cattttcaca tcccagtaat tcaggcgatc gcccagcgta ctgccatcgc
     8821 gcttttcccg ccctttatcg gcagcaagaa agaaattcat cccttgtaac ggcccttcgc
     8881 tgacccgata gttcatacca cctaagatac ccgtgccttc aatccgcaca tctcgtttac
     8941 tggattcata gccgcgagtc acaatcggtg caaatgtcag cgtaaattgc ggcgttaaac
     9001 gatagttgac gcccaattgc caggactgca ttccttcacg gttacgatca agacttaatg
     9061 aaaagggata gccaatgtcg gtatccacca cggcaccatt cattgcatgg cgcaaataac
     9121 caccactgcc aaatacactt ccccacggcg cattccaggt caattgtcca ctaaccaacg
     9181 ccgtttcatt gggctggctg gtattacgac ttaaaccttc gagctgcgcg taaaagccga
     9241 gcaactcccc tttcaacgta taattcgggt cgagcggtat gcttttctcg agaatacttt
     9301 gtatctgatt ggaaacatct ttctgtaccg atgcccccag agaatagcga ctggtatcat
     9361 catgccaact ggcggctaaa aaagaacgtg cgcgatgttt atcgtatttt cccgtctggc
     9421 tgttatacac cccttcatca cgaataccgg ttgttgaatc agtccataaa aatactcgtg
     9481 aacgccacat tccccacaga tcaatatttg gtgttaaagc ccaataacct aatgctcctt
     9541 cagaaactgt cggtaatgta cgttgcgaac tgccagccat taacggaata cgataaggta
     9601 agctaccata actataatcc gtcccgaagc gacctaattt aagcaggcta ttttcactgg
     9661 gttttatttt tactgccccc agggcaaagc caaaactttt atcaccatca agataccacc
     9721 gggtactcat atcagcacga gcacctaatt tataaacata atacgccccg ccttcaacgc
     9781 caataatatt ggaataataa ccactattga aatcgagcaa tcctccctgt acccatgcgt
     9841 aaaaatctct tcccgcgcca gcactgggct tatccgccct gcgcaattcg tttttcagtc
     9901 tgatgcgtag tcccgcttca tcgtcagcca gttgcgccgc ataagcagag gtaaggccag
     9961 aggcagccgt caggcaaata acggccatgg ccactatttt tctcatagtt gcacctttga
    10021 tgttctgatt atttttattg aatattaatt agtgatatcg ctgattaatt gctgctgcac
    10081 ttttttacga ttatcaattt caaccacgat ttctttgaat tttttatccg tgagcggata
    10141 aaaccagata ataacgaatg ccagtagcat aaatccgcaa ggtactaagg caattgatgt
    10201 gcggatgccc ataataactt ccggcgtttg cacctgattg gcgatatatc cgcttaaccc
    10261 caaaataaag gcaggaattg aacctccgat tgcctgaccg catttacggg taaatgagaa
    10321 tagtgaatag gtgagccctt caattcgcac gccggtcagg tattcaccgt attctacggt
    10381 atcagcttcc agcgcccaca tcacggtcat ggtaacgccc tgaccaattg aagcgatggc
    10441 caacgcaacc aacgccaccg gcagtgacca gacggaaacc cagaagaaca gcagataacc
    10501 gcaggttccc agcaaagcgc caatcaggaa ggtattcttt ttaccgatcc tcgcgaccat
    10561 ccccggcacc agcggtgccg atgccacagt accaaccagg ttttgcacca gtaccagcac
    10621 agtgaacagc ccggtatcat ttaacacata gcgcacgtag aacaacgacg aggcgctgac
    10681 cgcaaaggtc gaaatcagca cacacagcgc accgatgcac aacataaaca gcgggcgatt
    10741 ccgtttcagg gtttgcagac tgatattcaa tgacggctgc gcaacgatac gtaccacatt
    10801 ctcacgcgtc gatttgaagc agatgaagta aagcaccatt ccggcaatcg ccagcacaat
    10861 tgtccagaaa tggtataccg acaccatctc ttccgggctg gagttcttaa tgctcggtcc
    10921 tatcagaaat gccaggcaga caaaggtcaa tgaagcggca atcccacgag ccgcgcccag
    10981 acgggcgcgg gattgtggtt gttgggtcat cgcggtagca agtgaaccat aaggaatatt
    11041 caccaggctg tagcaaagcc cgaggcccat gtaggtcaaa tatgcataca ccactttgct
    11101 accatggctc cagtcggtcg gcacccagaa taccagcacg ctgaagatca ttaacggcgc
    11161 agtaccgaag agtaaaaacg ggcggaattt tccccagcgg gtattcacac tgtccaccac
    11221 tcgtccggca aagacgtcgg cgaaggcatc gaatacccgc accagtaaca gcatggtgcc
    11281 cgccgcagcg gcaccgacgc cagcgacgtc ggtgtagtaa ctcaacagga agagcgcccc
    11341 cattgcgaag gcgaagttat tggcgacgtc accgaggctg tagccgacga tggtgcgcca
    11401 ggagagttgt tgattcattg tttgcctccc tgctgcggtt tttcaccgaa gttcatgcca
    11461 gtccagcgtt tttgcagcag aaaagccgcc gacttcggtt tgcggtcgcg agtgaagatc
    11521 cctttcttgt taccgccaac gcgcaatatg ccttgcgagg tcgcaaaatc ggcgaaattc
    11581 catacctgtt caccgacgac ggcgctgacg cgatcaaaga cgcggtgata catatccagc
    11641 catgcacact gatactcttc actccacatg tcggtgtaca ttgagtgcag cccggctaac
    11701 gtatccacgc cgtattcggt gatgataatc ggctgatgca gtttctcctg ccaggccaga
    11761 agttcttttt ccagtacctt ctctgccgtt tccaaatcgc cgctttggac ataccatccg
    11821 taataacggt tcaggcacag cacatcaaag agatcgctga tggtatcggt gtgagcgtcg
    11881 cagaacatta cattgacgca ggtgatcgga cgcgtcgggt cgagtttacg cgttgcttcc
    11941 gccagtggcg cgaaatattc ccgtgcacct tgcggacggg tatccggttc gttggcaata
    12001 ctccacatca ccacgcttgg gtggtttttg tcacgcgcta tcagctcttt aatcgcctgt
    12061 aagtgcgctt gctgagtttc cccgttgact gcctcttcgc tgtacagttc tttcggcttg
    12121 ttgcccgctt cgaaaccaat gcctaaagag aggttaaagc cgacagcagc agtttcatca
    12181 atcaccacga tgccatgttc atctgcccag tcgagcatct cttcagcgta agggtaatgc
    12241 gaggtacggt aggagttggc cccaatccag tccattaatg cgtggtcgtg caccatcagc
    12301 acgttatcga atcctttgcc acgcaagtcc gcatcttcat gacgaccaaa gccagtaaag
    12361 tagaacggtt tgtggttaat caggaactgt tcgcccttca ctgccactga ccggatgccg
    12421 acgcgaagcg ggtagatatc acactctgtc tggcttttgg ctgtgacgca cagttcatag
    12481 agataacctt cacccggttg ccagaggtgc ggattcacca cttgcaaagt cccgctagtg
    12541 ccttgtccag ttgcaaccac ctgttgatcc gcatcacgca gttcaacgct gacatcacca
    12601 ttggccacca cctgccagtc aacagacgcg tggttacagt cttgcgcgac atgcgtcacc
    12661 acggtgatat cgtccaccca ggtgttcggc gtggtgtaga gcattacgct gcgatggatc
    12721 ccggcatagt taaagaaatc atggaagtaa gactgctttt tcttgccgtt ttcgtcggta
    12781 atcaccattc ccggcgggat agtctgccag ttcagttcgt tgttcacaca aacggtgata
    12841 cgtacacttt tcccggcaat aacatacggc gtgacatcgg cttcaaatgg cgtatagccg
    12901 ccctgatgct ccatcacttc ctgattattg acccacactt tgccgtaatg agtgaccgca
    12961 tcgaaacgca gcacgatacg ctggcctgcc caacctttcg gtataaagac ttcgcgctga
    13021 taccagacgt tgcccgcata attacgaata tctgcatcgg cgaactgatc gttaaaactg
    13081 cctggcacag caattgcccg gctttcttgt aacgcgcttt cccaccaacg ctgatcaatt
    13141 ccacagtttt cgcgatccag actgaatgcc cacaggccgt cgagtttttt gatttcacgg
    13201 gttggggttt ctacaggacg taacataagg gactcctcat taagataata atactggtca
    13261 acctttaatc tgattggtta accaattctg tgttgcacac agttatctgt gagaaaccca
    13321 tggaagagaa atggaaataa aaagaactga caccgcgatc aaaaaaccaa aaactgcaat
    13381 acccacagcg tgatatagat cgcattaatc tttaaaacag cgttgacaga agccataaaa
    13441 taagcaaccg aacgttcgtt cgagcgtatt gggaacgata aactctcatg acatatggct
    13501 acagtgaata ttttgggggg aattctccga agccgggaag gataattttt gcacagagaa
    13561 attacgatat gaaacgcggg cacagttatc accagcccgc cgaaaaagag agagaatcag
    13621 gatgcggtta agataccgcc aatcatcgcg cgtaatccct gagcaaacga cgcttcacgc
    13681 gccaggtctt ccgcttcgat atcggccagt acaccgtagg tcagatccag cagtaaacgt
    13741 gaagtcattg ccgtgttgat gtctgggctt atctcgcctt tttgctgggc atcacgcatc
    13801 cgctgggcaa caaattccgt gatcgtcata tgcttatttt taagcatggc ggcgacctgt
    13861 gggttacgca tcccttccgc cataatttca accaccagcg cccgttgtcc aaaggcttca
    13921 tgggtgagag agacaatgga ctcgaccata tagtcaacga aatgaatccc ttcaatcggt
    13981 tcccggaaac gggccagcgc cctctcctgg tcctgtaaga taatcgcctg aatcaaggct
    14041 tctttggaga tgaaatggtg atagagcgtc ccgggactaa tggcgcaaga tttacagatg
    14101 gctttcatcg aggcactgtg aaatccattt tctgaaaaaa tctctctggc agcattgagg
    14161 atccgggtcc gtgtcggttg tgcttcagtc tgcatgttat ccatcattaa accattatag
    14221 ttagcgtgaa taactagttt accgcgttgt caggtgagcg cctatcattg ctgttgaata
    14281 gtgcgaaggc acactctatt cgtatacttt tcactctgaa attggttaac caatagccgt
    14341 gatttggctg ccagttattt agcagagacg ttgatgagtt tatcccggta aacaacacgc
    14401 acggttgttt accggtccgt tagtgtatta attgagctcc tgtaccccac caccggagac
    14461 ggtgagaatt tgtccgctta cccagctcgc agcaggcgag caaaggaaca gcgctgcgtt
    14521 agcaatatct tgcggttggc ccagacgtct gatcggcgtg tgctgtaaca ttttttgttc
    14581 aatttctggt gtaataacgg atttcagggc atcggttaat attgcccccg gcgcaatgcc
    14641 atttacccga atattttttt cacccaggtc aaacgccata tttctgacca gatgactggc
    14701 cgcagcttta gatgatgcat aggaagtcat gtttatattt ttattttctg ccgccataga
    14761 agtgatggtc agaataacgc caccgccatt tttttccatt tctggcgcaa caagttgtga
    14821 cagatggaaa aaagaaaaca cattcagttc ataagcacgg cgaaaatccg ccattggcat
    14881 atcaaacggt ttaggtccac cgccaccggc gttgttaacc agaatatcaa ctttacccag
    14941 cttactgata gcaaagtctg ccagtgcaga gagttcctgt tcggaagtaa tatcacaacg
    15001 gcaggcaaat gcctgaccac ccagttgttg aatttcgtct acaacatggt tagctgcgtc
    15061 ggcgttaata tcactgacca ccacagatgc gccagctgtc gcgaatgtaa tggcgatttc
    15121 tttaccaata cctgcacccg cacctgtgat gatggcgcat tttccgtcga gtctcaggtt
    15181 gtcagaatta aacacataaa cctcctgtga acttcagtaa aaataaaagg caccgcctgt
    15241 gtgccacatt ttttatcatt aaccttgagg aaaggacact accaggtata gcagataaag
    15301 agaggattat ttcgctgcaa tgagccgggc gggaataata agattgcgtg aatgcgtctc
    15361 ttcatgggtg attttttgca tcatgcgatc cgcaagtgtg ataccaagtt cccgcgctgg
    15421 cgtgctggcc caggtaacag gtatatcatc aagtgtggtt ggtgtcgcat cggtaaatgc
    15481 cgccagcgaa acctgttgct caaagtaacg atcgactccg ctttccccgc tttgccgccc
    15541 tgctttgagc aaaccaaacc atgcccccat cgcaatagtt tcgttatagc aaaccacggc
    15601 actgatggtc gggttatgac gtaaaagcgc cgtgatagct tccgcggctt gcttctggct
    15661 ggaagtgcac tccaacaccc aatcgctatg aaacggcagg ccaaatttta gtagagttgc
    15721 acaatagccc ccaacccgtt ctgcacgggt taatgaggaa ctttgccctc ccagccaggc
    15781 gatccgctga tgcccattgc gaatgagatg ctccgtcaac aactgtgcag cctgcatgtt
    15841 gtccgggcga accgtatcaa catcatcaag ataactggca cgggaagcga aaatcaccgg
    15901 gatagctttt tcttctgcca tccgtcgcag gtcatcgcta cttcctgcag ctccggcaat
    15961 taccacacca tcgacaccct gattcagtaa cagtgaaaac cgctgtgcca gctgctcacc
    16021 gtctttaccg ccgtgaagca aaaaaaccat ccgtccctgc gcttccagag cttccgtcaa
    16081 tccggccgtc aattcggcgt aaaacggcgc agataaatca cggacgatca aaccaatgac
    16141 gccgctttgc ccgccgcgca gcgccgacgc ctggcgattg cgcacaaatc ccagctcttc
    16201 aatggcggcg ttaacgcgtt ctcctgtggc ggtagagatt cgccctttgc cactaagcac
    16261 cagcgaaacg gtacttaccg acacgcccgc agccagcgca acatcatgaa tggttatttt
    16321 tttggcggta gccatgcaga tgacctactc cctgattatg tgacagataa aacgttttac
    16381 cttttattta tcttataccc gctattatcg ttgcgtaatg tgatttatgc ctcactaaaa
    16441 tttgataaaa cgttttatct tctcgcgcaa tttactgaat ccagattgtt ctctacgagg
    16501 agtcgtttta tgacggcgaa aacagcaccg aaagtcacgc tgtgggagtt cttccagcag
    16561 ttaggcaaaa ccttcatgtt acccgtggca ttattgtcgt tctgcggcat tatgctcggc
    16621 attggtagtt ctcttagcag ccatgatgtc ataaccctga tcccggtcct gggcaacccc
    16681 gtgttgcagg ctatctttac ctggatgagt aagattggct cgtttgcttt tagtttcctg
    16741 cctgtcatgt tctgtatcgc catcccgctg ggcctggcac gcgaaaataa aggcgtagcg
    16801 gcattcgctg gcttcatcgg ttatgcggta atgaacctcg cggtaaactt ctggttgacc
    16861 aataaaggca ttctgccaac cacggatgcc gcggttctga aagccaataa catccagagc
    16921 attcttggga tccagtcgat cgataccggg atcctcggtg cggtgatcgc cggtattatc
    16981 gtctggatgc tgcatgagcg tttccataat atccgcctgc cggatgcgct ggcattcttc
    17041 ggcggtacgc gcttcgtacc aattatctcc tcgctggtga tgggccttgt cggcctggtg
    17101 attccattag tctggccgat tttcgccatg ggtattagcg gcttgggcca tatgataaac
    17161 agcgcgggtg atttcggacc gatgctgttt ggtaccggtg aacgtctgct gttgccgttt
    17221 ggtctgcatc acattctggt ggcattaatt cgctttaccg acgcaggcgg cacgcaggaa
    17281 gtctgcggtc aaaccgtcag cggcgcactg accatcttcc aggcgcaatt gagttgcccg
    17341 accactcacg gtttttctga aagcgccacg cgtttccttt cgcaaggtaa aatgcctgcg
    17401 tttctcggcg gtctgccagg tgcagcgtta gctatgtatc actgcgcgcg cccggaaaat
    17461 cgccataaaa ttaaaggtct gctgatttct ggcctgatcg cctgcgtcgt tggcggcact
    17521 accgaaccgc tggaattcct gttcctgttc gtagcgccag ttctgtatgt catccacgcg
    17581 ctgttaaccg gcctcggctt caccgtcatg tctgtgctcg gcgtcaccat cggtaatacc
    17641 gacggcaata tcatcgactt cgtggtgttc ggtattttgc atggtctgtc aaccaagtgg
    17701 tacatggtgc cagtggtggc ggcaatctgg tttgtcgttt actacgtcat cttccgtttc
    17761 gctatcaccc gcttcaatct gaaaaccccg gggcgcgata gcgaagttgc cagctcaatc
    17821 gaaaaagccg ttgccggtgc gccgggtaaa tcaggttaca acgttcctgc aatcctcgaa
    17881 gcattaggcg gtgccgacaa tattgtcagc ctcgataact gcattacccg tctgcgtttg
    17941 tctgtgaaag atatgtcgct tgttaatgtg caggcactga aggacaatcg ggcaattggc
    18001 gtagtacaac ttaatcaaca taacctgcag gttgttatcg ggccacaagt tcagtcagta
    18061 aaagatgaaa tggccggtct gatgcatact gtccaggcat aaggataaga tatgttcgat
    18121 ttttcaaagg tcgtggatcg tcatggcaca tggtgtacac agtgggatta tgttgctgac
    18181 cgtttcggca ctgctgacct gttaccgttc acgatttcag acatggattt tgccactgcc
    18241 ccctgcatta tcgaggcgct gaatcagcgc ctgatgcacg gcgtatttgg ctacagccgc
    18301 tggaaaaacg atgagtttct cgcggctatt gcccactggt tttccaccca gcattacacc
    18361 gccatcgatt ctcagacggt ggtgtatggc ccttctgtca tctatatggt ttcagaactg
    18421 attcgtcagt ggtctgaaac aggtgaaggc gtggtgatcc acacacccgc ctatgacgca
    18481 ttttacaagg ccattgaagg taaccagcgc acagtaatgc ccgttgcttt agagaagcag
    18541 gctgatggtt ggttttgcga tatgggcaag ttggaagccg tgttggcgaa accagaatgt
    18601 aaaattatgc tcctgtgtag cccacagaat cctaccggga aagtgtggac gtgcgatgag
    18661 ctggagatca tggctgacct gtgcgagcgt catggtgtgc gggttatttc cgatgaaatc
    18721 catatggata tggtttgggg cgagcagccg catattccct ggagtaatgt ggctcgcgga
    18781 gactgggcgt tgctaacgtc gggctcgaaa agtttcaata ttcccgccct gaccggtgct
    18841 tacgggatta tagaaaatag cagtagccgc gatgcctatt tatcggcact gaaaggccgt
    18901 gatgggcttt cttccccttc ggtactggcg ttaactgccc atatcgccgc ctatcagcaa
    18961 ggcgcgccgt ggctggatgc cttacgcatc tatctgaaag ataacctgac gtatatcgca
    19021 gataaaatga acgccgcgtt tcctgaactc aactggcaga tcccacaatc cacttatctg
    19081 gcatggcttg atttacgtcc gttgaatatt gacgacaacg cgttgcaaaa agcacttatc
    19141 gaacaagaaa aagtcgcgat catgccgggg tatacctacg gtgaagaagg tcgtggtttt
    19201 gtccgtctca atgccggctg cccacgttcg aaactggaaa aaggtgtggc tggattaatt
    19261 aacgccatcc gcgctgttcg ttaaccccaa ttgcgcaacg taaaaaatcg ttgcgcaatc
    19321 gtggattttt accctgcttt gtttttataa tggtgcgcac ttttatatcc agaaaaagag
    19381 tgcgaccatg attgatacca ccctgccatt aactgatatc catcgccacc ttgatggcaa
    19441 cattcgtccc cagaccattc ttgaacttgg ccgccagtat aatatctcgc ttcctgcaca
    19501 atccctggaa acactgattc cccacgttca ggtcattgcc aacgaacccg atctggtgag
    19561 ctttctgacc aaacttgact ggggcgttaa agttctcgcc tctcttgatg cctgtcgccg
    19621 cgtggcattt gaaaacattg aagatgcagc ccgtcacggc ctgcactatg tcgagctgcg
    19681 tttttcacca ggctacatgg caatggcaca tcagctgcct gtagcgggtg ttgtcgaagc
    19741 ggtgatcgat ggcgtacgtg aaggttgccg cacctttggt gtgcaggcga agcttatcgg
    19801 cattatgagc cggaccttcg gcgaagccgc ctgtcagcaa gagctggagg cctttttagc
    19861 ccaccgtgac cagattaccg cacttgattt agccggtgat gaacttggtt tcccgggaag
    19921 tctgttcctt tctcacttca accgcgcgcg tgatgcgggc tggcatatta ccgtccatgc
    19981 aggcgaagct gccgggccgg aaagcatctg gcaggcgatt cgtgaactgg gtgcggagcg
    20041 tattggacat ggcgtaaaag ccattgaaga tcgggcgctg atggattttc tcgccgagca
    20101 acaaattggt attgaatcct gtctgacctc caatattcag accagcaccg tagcagagct
    20161 ggctgcacat ccgctgaaaa cgttccttga gcatggcatt cgtgccagca ttaacactga
    20221 cgatcccggc gtacagggag tggatatcat tcacgaatat accgttgccg cgccagctgc
    20281 tgggttatcc cgcgagcaaa tccgccaggc acagattaat ggtctggaaa tggctttcct
    20341 cagcgctgag gaaaaacgcg cactgcgaga aaaagtcgcc gcgaagtaac aaaatggatg
    20401 gtgcaaatgc accatccatt tttcatgcaa ggcacaaagt cgcgcgatgt ttggcggatt
    20461 cgatgcccag ctcaatcaac tccattacct ggattgcctg gcttgccgga accggatttt
    20521 caccatcgcc atttaacgca tcacgaatag ccgcatagta agccggataa ttcccaggca
    20581 ccggcaccgt caacagcgtt tcttcgacac gttcctcacc ttccacgcgg gtaagtacgc
    20641 catcacgcat atcgtagccc cagtcttcct gcggtagacg ctcgccattt ttcagacgtt
    20701 cttcctgtgg atcgaggcca tatttcacat aactgcctcg ggatccatgc acgatatacc
    20761 gtgctgactc agcggctgcc agcatggtac cgtgtaaaat gactcgccgc tgtggatagg
    20821 acaagatggc gtggaaataa tcggtcgact gcgctccggg ccgtaactgt gccaaatcta
    20881 ccgtcatgct gaccggtaaa ccaaaaagcg taatggcctg atcaagaaga tgtggtgcta
    20941 aatcgtacca gataccgctg cctgggccgc cctgttcacg ccaacgatcg cgcacctgcg
    21001 gacggaagcg gtcaaaatga gactcaaagt aagcaacttc acccagcacg ccttccgcga
    21061 gtaaaccttt tagcgtcaag aaatcgctat cccagcgacg gttatggaat acagacagca
    21121 cacgccccag gctttttgcc agcgcatcca gctctcgcgc ttgtgacagt gtcacggtaa
    21181 agggtttatc aacgaccaca tgtttacccg cctcaagcgc cgctttggct aacgggaaat
    21241 gggtatcgtt gggtgtagga atgacaatca ggtctatgtt gggatcgtta aacagatgct
    21301 tcggctcaga gacaaccgta accgttggcc agtcggcttt tacttttgtt tcatcactgc
    21361 tggagattac cgccagttcc agcccaggcg tgcccgcaat caggggcgca tggaaggttt
    21421 tgctcgcata accataccca atcaacccaa cacggatgtt gtcgctcatg tcattgcctc
    21481 tcattgaagt atgatggcta tttgacacta tcctttaccc acgctcaaca gtttaataac
    21541 ctgccagcaa taagggatgt tgtttaactt aagtcaaaaa aatagcgaat tttccaacga
    21601 caaaagctaa atatcgcaaa aacctcagta aaaatcttgc tggagctatt attgctaagt
    21661 aacatttacc ccctgaagtt aatggatcaa tcaagagaga tgtgggctgt aatgaatcgt
    21721 cttattgaat taacaggttg gatcgttctt gtcgtttcag tcattcttct tggcgtggcg
    21781 agtcacattg acaactatca gccacctgaa cagagtgctt cggtacaaca caagtaagct
    21841 ctgcacttgt ggagcgacat gctgcccgtc cgggtgcatg ttttcacttg tcggatatta
    21901 aaccaggaat ttattatctt gttcgatgtt gttggtgatt gtcagggata gtaaagcgcg
    21961 ttactctttt cagagcagtt tttcatccct gaatatttgc catcagcgca ttcttattat
    22021 tgtaataaca caagcgttca cttttggtga aattttatca tcactaataa tacctacccc
    22081 tttggtatta attattttat ggacctttta tgactgttca ggactactta ttaaaatttc
    22141 gcaaaatcag ttcactcgaa agtctggaaa aactctacga ccatcttaat tacaccctga
    22201 cggacgatca ggaactgatc aatatgtatc gtgctgccga tcaccgtcgc gcagagctgg
    22261 tttctggcgg gcgtttgttt gacctcggcc aggtaccgaa gtccgtctgg cactatgtcc
    22321 aataaagaaa gtagcgatcg gttataaaag ccttataata acgcccctaa aattagattt
    22381 gcctgtttgc gtcgctattc tggagaacct atgaccacca caacgccaca acgtattgga
    22441 ggctggttgc ttggcccgtt ggcctggctt ttagtcgctc tgttgagtac gacgctggcg
    22501 ttgttgctgt ataccgctgc gttatcttct ccgcaaacat ttcaaacgct cggcggacaa
    22561 gcactgacga cacaaatctt atggggcgtt tcttttatta ccgctatcgc cttgtggtat
    22621 tacacactgt ggttgaccat cgctttcttt aaacgtcggc gttgtgttcc taaacactat
    22681 attatctggc tgcttatttc cgtattgctg gcagtaaaag cattcgcttt ttcacccgtg
    22741 gaagatggca tagccgttcg ccagttgctg tttactttgt tggcaaccgc attgatcgtc
    22801 ccctatttca aacgctcgtc gcgggtaaaa gcgacgtttg tgaatccgta ataaccttac
    22861 agttaacctg ttgtcgcctg ctctggatta acggataata ggcggctttt ttatttcagg
    22921 ccgaaaaatg actgactacc tgttactgtt tgtcggaact gtactggtca ataactttgt
    22981 actggtcaag tttctcggtc tctgtccgtt tatgggggtt tccaaaaaac tggaaaccgc
    23041 gatgggcatg gggctggcaa caacgtttgt gatgacgctg gcgtctattt gcgcctggct
    23101 tatcgatacg tggattttga tcccacttaa tctgatttac ctgcgcaccc tggcatttat
    23161 tctggtgatt gctgtggtcg tgcagttcac cgagatggtg gtgcgcaaaa ccagcccggt
    23221 gctttaccgt ctgctgggga tttttttgcc gcttatcacc accaactgtg cagtgctcgg
    23281 cgtggcgttg ctgaatatca atctcgggca caatttcttg cagtcggcgc tgtacggttt
    23341 ttccgccgct gtcggtttct cgctggtgat ggtgctcttc gccgccatcc gcgaacgcct
    23401 tgctgtggct gatgtcccgg caccttttcg cggtaatgcc attgcgttaa ttaccgcagg
    23461 tcttatgtct ctggccttta tgggctttag tggtttggtg aagttgtaat gaatgctatc
    23521 tggattgccg ttgccgccgt gagcctgctg ggcctggcgt ttggcgccat tctgggttat
    23581 gcctcccgcc gttttgcggt ggaagacgat ccggtcgttg agaaaattga cgaaatctta
    23641 ccgcagagcc agtgtggtca gtgcggttat cccggctgtc gcccctacgc ggaagccatc
    23701 agctgtaacg gtgaaaaaat caaccgttgc gccccaggtg gcgaagctgt gatgctaaaa
    23761 attgccgagt tgcttaatgt cgagccgcag ccgctggatg gcgaagcgca agagataacg
    23821 cctgcgcgga tggtggcggt tattgatgaa aataactgta ttggctgcac taaatgtatt
    23881 caggcgtgtc cggtagacgc catcgttggc gctacccgtg ccatgcatac ggtaatgagt
    23941 gatctctgta cgggctgcaa tttatgtgtt gatccgtgcc cgacgcactg catctcgttg
    24001 caaccggtcg cagaaacacc tgactcctgg aaatgggatc tgaacaccat tcccgtgcgt
    24061 atcattcccg tggaacacca tgcttaagtt attctctgca ttcagaaaaa ataaaatctg
    24121 ggatttcaac ggcggcatcc atccaccgga gatgaaaacc cagtccaacg gtacacccct
    24181 gcgccaggta cccctggcgc agcgttttgt tattccactg aaacagcata ttggcgctga
    24241 aggtgagttg tgcgttagcg tcggcgataa agtattgcgc ggccagccgc ttacccgtgg
    24301 tcgcggcaaa atgctgcctg ttcacgcgcc cacctcgggt accgttacgg ctattgcgcc
    24361 ccactctacg gctcatcctt cagctttagc tgaattaagc gtgattattg atgccgatgg
    24421 tgaagactgc tggatcccgc gcgacggctg ggccgattat cgcactcgca gtcgcgaaga
    24481 gttaatcgag cgcatacatc agtttggtgt tgccgggctg ggcggtgcag gattcccgac
    24541 aggcgttaaa ttgcagggtg gcggagataa gattgaaacg ttgattatca acgcggctga
    24601 gtgcgagccg tacattaccg ccgatgaccg tttgatgcag gattgcgcgg ctcaggtcgt
    24661 agagggtatt cgcattcttg cgcatattct gcagccacgc gaaattctta tcggcattga
    24721 agataacaaa ccgcaggcga tttccatgct gcgcgcggtg ctggcggact ctaacgatat
    24781 ttctctgcgg gtgattccaa ccaaatatcc ttctggcggt gctaaacaat taacctacat
    24841 tctgaccggg aagcaggttc cacatggcgg gcgttcatcc gatatcggcg tattaatgca
    24901 aaacgtcggc actgcttatg cagtgaaacg tgccgttatt gatggcgagc cgattaccga
    24961 gcgtgttgta accctgactg gcgaagcaat cgctcgcccg ggcaacgtct gggcacggct
    25021 ggggacgcca gtgcgtcatt tattgaatga tgccggattc tgcccctctg ccgatcaaat
    25081 ggtgattatg ggtggcccgc taatgggctt taccttgcca tggctggatg tcccggtcgt
    25141 aaagattacc aactgtctgt tggctccctc tgccaatgaa cttggcgaac cacaggaaga
    25201 acaaagctgc atccggtgta gcgcctgtgc tgacgcctgc cctgcggatc ttttgccgca
    25261 acagttgttc tggttcagca aaggtcagca acacgataaa gctaccacgc ataacattgc
    25321 tgattgcatt gaatgtgggg cttgcgcgtg ggtttgcccg agcaatattc ccctggtgca
    25381 atatttccgt caggaaaaag ctgaaattgc ggctattcgt caggaagaaa agcgcgccgc
    25441 agaagccaaa gcgcgtttcg aagcgcgcca ggctcgtctg gagcgcgaaa aagcggctcg
    25501 ccttgaacga cataagagcg cagccgttca acctgcagcc aaagataaag atgcgattgc
    25561 tgccgctctg gcgcgggtga aagagaaaca ggcccaggct acacagccta ttgtgattaa
    25621 agcgggcgaa cgcccggata acagtgcaat tattgcagca cgggaagccc gtaaagcgca
    25681 agccagagcg aaacaggcag aactgcagca aactaacgac gcagcaaccg ttgctgatcc
    25741 acgtaaaact gccgttgaag cagctatcgc ccgcgccaaa gcgcgcaagc tggaacagca
    25801 acaggctaat gcggaaccag aacaacaggt cgatccgcgc aaagccgccg tcgaagccgc
    25861 tattgcccgt gccaaagcac gcaagctgga acagcaacag gctaatg
//
LOCUS       DACAOP010000062        25705 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.062, whole genome shotgun sequence.
ACCESSION   DACAOP010000062 DACAOP010000000
VERSION     DACAOP010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25705
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.062"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(34..756)
                     /gene="sdiA"
                     /locus_tag="IT892_002846"
     CDS             complement(34..756)
                     /gene="sdiA"
                     /locus_tag="IT892_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="HAP3136043.1"
                     /translation="MQDTDFFSWRRTMLLRFQRMEAAEEVYHEIELQAQQLEYDYYSL
                     CVRHPVPFTRPKVAFYTNYPEAWVSYYQAKNFLAIDPVLNPENFSQGHLMWNDDLFSE
                     AQPLWEAARAHGLRRGVTQYLMLPNRALGFLSFSRCSAREIPILSDELQLKMQLLVRE
                     SLMALMRLNDEIVMTPEMNFSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQKNM
                     QKKINAPNKTQVACYAAATGLI"
     gene            complement(986..1738)
                     /gene="yecC"
                     /locus_tag="IT892_002847"
     CDS             complement(986..1738)
                     /gene="yecC"
                     /locus_tag="IT892_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     YecC"
                     /protein_id="HAP3136044.1"
                     /translation="MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTT
                     LLRSINLLEQPEAGTITVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTV
                     LENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA
                     MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMD
                     QGRIVEQGAAKALFADPQQPRTRQFLEKFLLQ"
     gene            complement(1735..2403)
                     /gene="tcyL"
                     /locus_tag="IT892_002848"
     CDS             complement(1735..2403)
                     /gene="tcyL"
                     /locus_tag="IT892_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="HAP3136045.1"
                     /translation="MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMR
                     LSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAY
                     AAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
                     SLAATIQVPELFRQAQLITSRTLDVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQE
                     REPK"
     gene            complement(2418..3404)
                     /gene="dcyD"
                     /locus_tag="IT892_002849"
     CDS             complement(2418..3404)
                     /gene="dcyD"
                     /locus_tag="IT892_002849"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416429.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="HAP3136046.1"
                     /translation="MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTP
                     MAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENP
                     IGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGG
                     SNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGV
                     TVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLA
                     RLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV"
     gene            complement(3509..4309)
                     /gene="tcyJ"
                     /locus_tag="IT892_002850"
     CDS             complement(3509..4309)
                     /gene="tcyJ"
                     /locus_tag="IT892_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3136047.1"
                     /translation="MKLAHLGRQALMGVMAVALVAGMSVKSFADEGLLNKVKERGTLL
                     VGLEGTYPPFSFQGDDGKLTGFEVEFAQQLAKHLGVEASLKPTKWDGMLASLDSKRID
                     VVINQVTISDERKKKYDFSTPYTISGIQALVKKGNEGTIKTAADLKGKKVGVGLGTNY
                     EEWLRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNDTLAVTGEA
                     FSRQESGVALRKGNEDLLKAVNDAIAEMQKDGTLQALSEKWFGADVTK"
     gene            complement(4397..4948)
                     /gene="fliZ"
                     /locus_tag="IT892_002851"
     CDS             complement(4397..4948)
                     /gene="fliZ"
                     /locus_tag="IT892_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310687.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliZ"
                     /protein_id="HAP3136048.1"
                     /translation="MMVQHLKRRPLSRYLKDFKHSQTHCAHCRKLLDRITLVRDGKIV
                     NKIEISRLDALLDENGWQTEQKSWAALCRFCGDLHCKTQSDFFDIIGFKQFLFEQTEM
                     SPGTVREYVVRLRRLGNHLHEQNISLDPLQDGFLDEILAPWLPTTSTNNYRIALRKYQ
                     HYQRQTCSGLVQKSSSLPASDIY"
     gene            complement(4994..5713)
                     /locus_tag="IT892_002852"
     CDS             complement(4994..5713)
                     /locus_tag="IT892_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FliA"
                     /protein_id="HAP3136049.1"
                     /translation="MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDL
                     LQAGGIGLLNAVERYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQ
                     AIGQLEQELGRNATETEVAERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELV
                     TDDHQRENPLQQLLDSNLRQRVMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGE
                     SRVSQLHSQAIKRLRTKLGKL"
     gene            complement(6033..7295)
                     /locus_tag="IT892_002853"
     CDS             complement(6033..7295)
                     /locus_tag="IT892_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliC/FljB family flagellin"
                     /protein_id="HAP3136050.1"
                     /translation="MAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDD
                     AAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGALSEINNNLQRVRELTVQATTG
                     TNSESDLSSIQDEIKSRLEEIDRVSSQTQFNGVNVLAKDGKMNIQVGANDGQTITIDL
                     KKIDSSTLNLSSFDATNLGTSVKDGATINKQVAVGAGDFKDKASGSLGTLKLVEKDGK
                     YYVNDTKSSKYYDAEVDTSKGEINFNSTNESGTTPTAATEVTTVGRDVKLDASALKAN
                     QSLVVYKDKSGNDAYIIQTKDVTTNQSTFNAANISDAGVLSIGASTTAPSNLTADPLK
                     ALDDAIASVDKFRSSLGAVQNRLDSAIANLNNTTTNLSEAQSRIQDADYATEVSNMSK
                     AQIIQQAGNSVLAKANQVPQQVLSLLQG"
     gene            7561..8967
                     /gene="fliD"
                     /locus_tag="IT892_002854"
     CDS             7561..8967
                     /gene="fliD"
                     /locus_tag="IT892_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HAP3136051.1"
                     /translation="MASISSLGVGSGLDLSSILDSLTAAQKATLTPISNQQSSFTAKL
                     SAYGTLKSALTTFQTANTALSKADLFSATSTTSSTTAFSATTAGNAIAGKYTISVTHL
                     AQAQTLTTRTTRDDTKTAIATSDSKLTIQQGGDKDPISIDISAANSSLSGIRDAINNA
                     KAGVSASIINVGNGEYRLSVTSNDTGLDNAMTLSVSGDDALQSFMGYDASASSNGMEV
                     SVAAQNAQLTVNNVAIENSSNTISDALENITLNLNDVTTGNQTLTITQDTSKAQTAIK
                     DWMNAYNSLIDTFSSLTKYTAVDAGADSQSSSNGALLGDSTLRTIQTQLKSMLSNTVS
                     SSNYKTLAQIGITTDPSDGKLELDADKLTAALKKDASGVGALIVGDGKKTGITTTIGS
                     NLTSWLSTTGIIKAATDGVSKTLNKLTKDYNAASDRIDAQVARYKEQFTQLDVLMTSL
                     NSTSSYLTQQFENNSNSK"
     gene            8992..9402
                     /gene="fliS"
                     /locus_tag="IT892_002855"
     CDS             8992..9402
                     /gene="fliS"
                     /locus_tag="IT892_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HAP3136052.1"
                     /translation="MYAAKGTQAYAQIGVESAVMSASQQQLVTMLFDGVLSALVRARL
                     FMQDNNQQGKGVSLSKAINIIENGLRVSLDEESKDELTQNLIALYSYMVRRLLQANLR
                     NDVSAVEEVEALMRNIADAWKESLLTPSLIQDPV"
     gene            9402..9767
                     /gene="fliT"
                     /locus_tag="IT892_002856"
     CDS             9402..9767
                     /gene="fliT"
                     /locus_tag="IT892_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliT"
                     /protein_id="HAP3136053.1"
                     /translation="MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAV
                     QEIAHLTEEIDPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSV
                     LSAYGDQGGFVLAPQDNLS"
     gene            9845..11332
                     /gene="amyA"
                     /locus_tag="IT892_002857"
     CDS             9845..11332
                     /gene="amyA"
                     /locus_tag="IT892_002857"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HAP3136054.1"
                     /translation="MRNPTLLQCFHWYYPEGGKLWPELAERADGFNDIGINMVWLPPA
                     YKGASGGYSVGYDSYDLFDLGEFDQKGSIPTKYGDKAQLLAAIDALKRNDIAVLLDVV
                     VNHKMGADEKEAIRVQRVNADDRTQIDEEIIECEGWTRYTFPARAGQYSQFIWDFKCF
                     SGIDHIENPDEDGIFKIVNDYTGEGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKY
                     WARWVMEQTQCDGFRLDAVKHIPAWFYKEWIEHVQEVAPKPLFIVAEYWSHEVDKLQT
                     YIDQVEGKTMLFDAPLQMKFHEASRMGRDYDMTQIFTGTLVEADPFHAVTLVANHDTQ
                     PLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGAHYEDVGGDGHTYPIDMPII
                     EQLDELILARQRFAHGVQTLFFDHPNCIAFSRSGTDEYPGCVVVMSNGDDGEKTIHLG
                     ENYGNKTWRDFLGNRQESVVTDENGEATFFCNGGSVSVWVIEEVI"
     gene            complement(11366..11779)
                     /locus_tag="IT892_002858"
     CDS             complement(11366..11779)
                     /locus_tag="IT892_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310694.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP3136055.1"
                     /translation="MKKLAIAGALMLLAGCAEVENYNNVVKTPAPDWLAGYWQTKGPQ
                     RALVSPEAIGSLIVTKEGDTLDCRQWQRVIAVPGKLTLMSDDLTNVTVKRELYEVERD
                     GNTIEYDGMTMERVDRPTAECAAALDKAPLPTPLP"
     gene            11966..13171
                     /gene="yedE"
                     /locus_tag="IT892_002859"
     CDS             11966..13171
                     /gene="yedE"
                     /locus_tag="IT892_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism membrane protein YedE/FdhT"
                     /protein_id="HAP3136056.1"
                     /translation="MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGE
                     FTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRIDGMMILGMFGGCFAAALWANNVK
                     LRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
                     FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGLLGWALLTAMNQ
                     PKLGLAMLFGVGFGLLIERAQICFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYV
                     QLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQVHYWWVGLGNVIGS
                     TILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFAALMLIIGWEKRFFRRA
                     APQTAKEIA"
     gene            13168..13401
                     /gene="yedF"
                     /locus_tag="IT892_002860"
     CDS             13168..13401
                     /gene="yedF"
                     /locus_tag="IT892_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HAP3136057.1"
                     /translation="MKNIVPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCP
                     QSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK"
     gene            13510..14007
                     /locus_tag="IT892_002861"
     CDS             13510..14007
                     /locus_tag="IT892_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000334561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136058.1"
                     /translation="MCGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKV
                     LLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSHMFKPLWQHGRAICFADG
                     WFEWKKEGDKKQPYFIYRADGQAVFIAAIGSTPFERGDEAGRSFCKPAQGLSVTVAMA
                     VRANL"
     gene            complement(13889..14218)
                     /locus_tag="IT892_002862"
     CDS             complement(13889..14218)
                     /locus_tag="IT892_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001324015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP3136059.1"
                     /translation="MKRLQAFKFRLRPGGQQEREMRRFAGACRFVFNRALALQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDPERAYKNFFRLRHHAQT
                     VCYLSRL"
     gene            14241..14765
                     /gene="tnpA"
                     /locus_tag="IT892_002863"
     CDS             14241..14765
                     /gene="tnpA"
                     /locus_tag="IT892_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAP3136060.1"
                     /translation="MKKETDIRRGRHCVFLKHVHLVFVTKYRRQIFDHDATEKLRTYF
                     SNVCADFEAERVEMDGGPDHVHLLINYPPKLAISSLVNSLKGVSSRLLRRDRPDIAVR
                     YYDKGVLWSPGYFVSSCILTYQLDLITTISAPNRISNVISIPLIIPSTSCNFPTLELH
                     IVQTPDAKKSHVHF"
     gene            14891..15871
                     /locus_tag="IT892_002864"
     CDS             14891..15871
                     /locus_tag="IT892_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000019445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element ISKpn26 family transposase"
                     /protein_id="HAP3136061.1"
                     /translation="MSHQLTFADSEFSTKRRQTRKEIFLSRMEQILPWQNMVEVIEPF
                     YPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDR
                     TTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQR
                     DPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVS
                     ADAGYQGAPQREELAEVDVDWLIAERPGKVKTLKQHPRKNKTAINIEYMKASIRARVE
                     HPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRVDQMIRQWERSQ"
     gene            16021..16455
                     /gene="rcsA"
                     /locus_tag="IT892_002865"
                     /pseudo
     CDS             16021..16455
                     /gene="rcsA"
                     /locus_tag="IT892_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707836.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
     gene            complement(16499..16741)
                     /gene="dsrB"
                     /locus_tag="IT892_002866"
     CDS             complement(16499..16741)
                     /gene="dsrB"
                     /locus_tag="IT892_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="HAP3136062.1"
                     /translation="MPEKRNCSTLAQRHRRKTMKVNDRVTVKTDGGPRRPGVVLAVEE
                     FSEGTMYLVSLEDYPLGIWFFNEAGHQDGIFVEKAE"
     gene            16850..17077
                     /gene="yodD"
                     /locus_tag="IT892_002867"
     CDS             16850..17077
                     /gene="yodD"
                     /locus_tag="IT892_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416463.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid resistance protein YodD"
                     /protein_id="HAP3136063.1"
                     /translation="MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQNDSEHV
                     SVDGREYHTWRELADAFELDIHDFSVSEVNR"
     gene            17375..18190
                     /locus_tag="IT892_002868"
     CDS             17375..18190
                     /locus_tag="IT892_002868"
                     /EC_number="3.1.3.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-3-phosphoglycerate phosphatase-related
                     protein"
                     /protein_id="HAP3136064.1"
                     /translation="MLSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLRGANVPVI
                     LCSSKTSAEMLYLQKTLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGITHGEIIQ
                     VLNTLREKEHFKFTTFDDVDDETIAEWTGLNRSQAALTQLHEASVTLIWRDSDERMAQ
                     FTARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQSLGKRPTTLGLGDGPND
                     APLLEVMDYAVIVKGLNRQGVHLHDEDPARVWRTQREGPEGWREGLDHFFSAR"
     gene            complement(18226..19881)
                     /gene="yedQ"
                     /locus_tag="IT892_002869"
     CDS             complement(18226..19881)
                     /gene="yedQ"
                     /locus_tag="IT892_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator YedQ"
                     /protein_id="HAP3136065.1"
                     /translation="MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWRE
                     VVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAV
                     TEFEQHRDEHAWQIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYL
                     LRLAHNSSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFVGHSQRENRH
                     RAVRWFTSQPEHASNTEPQVTVSVPVDSENYWYGVLGMSIPVRTMQQFLRNAIDKNLD
                     GEYQLYDSKLRLLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMNSRYVSWERL
                     DHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMASNMYVLQS
                     SLQWQAWHDTLTRLYNRGALFEKARSLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQ
                     AGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILPGASLTQAAEVAERIRLKLNEKE
                     MLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAK"
     gene            complement(20052..20234)
                     /locus_tag="IT892_002870"
     CDS             complement(20052..20234)
                     /locus_tag="IT892_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2158 domain-containing protein"
                     /protein_id="HAP3136066.1"
                     /translation="MSFMVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGYGVKREAFH
                     ETELVPGEGSRSAEEV"
     gene            complement(20313..21230)
                     /locus_tag="IT892_002871"
     CDS             complement(20313..21230)
                     /locus_tag="IT892_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
                     /protein_id="HAP3136067.1"
                     /translation="MLLAGSSLLTLLDDIATLLDDISVMGKLAAKKTAGVLGDDLSLN
                     AQQVSGVRANRELPVVWGVAKGSLINKVILVPLALIISAFIPWAITPLLMIGGAFLCF
                     EGVEKVLHMLEARKHKEDPAQSQQRLEKLAAQDPLKFEKDKIKGAIRTDFILSAEIVA
                     ITLGIVAEAPLLNQVLVLSGIALVVTVGVYGLVGVIVKIDDLGYWLAEKSSALMQALG
                     KGLLIIAPWLMKALSIVGTLAMFLVGGGIVVHGIAPLHHAIEHFAGQQSAVVAMILPT
                     VLNLILGFIIGGIVVLGVKAVAKMRGQAH"
     gene            21403..22323
                     /gene="yedA"
                     /locus_tag="IT892_002872"
     CDS             21403..22323
                     /gene="yedA"
                     /locus_tag="IT892_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="HAP3136068.1"
                     /translation="MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRF
                     LAAGILLMAFLLLRGHKLPPLRPLLNAALIGLLLLAVGNGMVTVAEHQNVPSGIAAVV
                     VATVPLFTLCFSRLFGIKTRKLEWVGIAIGLAGIIMLNSGGNLSGNPWGAILILIGSI
                     SWAFGSVYGSRITLPVGMMAGAIEMLAAGVVLMIASMIAGEKLTALPSLSGFLAVGYL
                     ALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGEKLSKIEWLALGVI
                     VFAVVLVTLGKYLFPAKPVVAPVIQDASSE"
     gene            complement(22312..22782)
                     /locus_tag="IT892_002873"
     CDS             complement(22312..22782)
                     /locus_tag="IT892_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="very short patch repair endonuclease"
                     /protein_id="HAP3136069.1"
                     /translation="MADVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDA
                     SLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPATRTEFWLEKIGKNVERDRRDIS
                     RLQELGWRVLIVWECALRGREKLTDEALIERLEEWICGEGASAQIDTQGIHLLA"
     gene            complement(22763..24181)
                     /locus_tag="IT892_002874"
     CDS             complement(22763..24181)
                     /locus_tag="IT892_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HAP3136070.1"
                     /translation="MQENISVTDSYSTGNAAQAMLEQLLQIYDVKTLVAHLNGVGENH
                     WSAAILKRALANDSAWHRLSDKEFAHLQTLLPIPPAHHPHYAFRFIDLFAGIGGIRRG
                     FESIGGQCVFTSEWNKHAVRTYKANYYCDPAVHHFNEDIRDITLSHKEGIGDDVAAEH
                     IRQHIPEHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFACDTQGTLFFDVVRIIDARRP
                     AIFVLENVKNLKSHDQGKTFRIIMQTLDELGYDVADAEDNGPDDPKIIDGKHFLPQHR
                     ERIVLVGFRRDLNLKADFTLRDISGCFPAQRVTLAQLLDPMVEAKYILTPVLWKYLYR
                     YAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRGWDMATGEKDFDDP
                     LNQQHRPRRLTPRECARLMGFEAPGEAKFRIPVSDTQAYRQFGNSVVVPVFAAVAKLL
                     EPKIKQAVALRQQEAQHGRRSR"
     gene            complement(24248..24943)
                     /locus_tag="IT892_002875"
     CDS             complement(24248..24943)
                     /locus_tag="IT892_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAP3136071.1"
                     /translation="MDLQHWQAQFENWLKNHHQHQDAAHDVCHFRRVWATAQKLAADD
                     DVDMLVILTACYFHDIVSLAKNHPQRQRSSILAAEETRRLLREEFEQFPAEKIEAVCH
                     AIAAHSFSAQIAPLTAEAKIVQDADRLEALGAIGLARVFAVSGALGVALFDGEDPFAQ
                     HRPLDDKRYALDHFQTKLLKLPHTMQTIKGKQLAQYNAQFLVEFMAKLSAELAGENEG
                     IDHKVIDTFSPVG"
     gene            complement(24983..25348)
                     /locus_tag="IT892_002876"
     CDS             complement(24983..25348)
                     /locus_tag="IT892_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAP3136072.1"
                     /translation="MEKCDFYHIIVLSLNFPGYLKMEYGSTKMEERISRSPGGKLALW
                     AFYTWCGYFVWAMARYIWVMSRIPDAPVSGFESDLGSTAGKWLGALVGFLFMALVGAL
                     LGSIAWYTRPRPARSRRYE"
BASE COUNT         6390 a         6710 c         6217 g         6388 t
ORIGIN      
        1 gtttttgcat ctggcacgca gaaagaaaag cgatcaaatt aagccagtag cggccgcgta
       61 acaggccacc tgggtcttat ttggtgcatt gatttttttc tgcatgtttt tctgatggaa
      121 attgaccgta ttctcagaga ttgacaaaat catcgctatc tctgctgatg tcttcccttc
      181 cgccgtccat ttcagaattt ctttttcgcg cttgctgaaa ttcatctctg gcgtcatcac
      241 tatttcatca tttaaacgca tcagagccat cagactttcg cgcaccagta actgcatttt
      301 taattgcagt tcatcactaa gaatgggtat ttcgcgagcg ctgcaacggg aaaaggacaa
      361 aaagcccaac gcccgatttg gcagcattaa atactgagtg acaccgcggc gtaaaccatg
      421 tgcgcgcgcg gcttcccata acggctgtgc ttcgctgaat aagtcatcat tccacattaa
      481 atggccctga ctaaagtttt cagggttcag caccggatca attgcgagaa agttttttgc
      541 ctgataataa ctaacccacg cctcagggta attggtgtag aaagccactt taggtcgcgt
      601 gaatggtacc gggtggcgaa cacataacga atagtaatcg tactccagct gctgagcctg
      661 aagctctatt tcatggtaga cctcttctgc ggcctccatc ctctgaaaac gcaacagcat
      721 cgtgcgacgc cagctgaaaa aatccgtatc ctgcatagta aaccgcaacg cccctgagag
      781 tgagtatcat ttataatgat aattcaaact atcacataaa taagatttat atataattta
      841 tattattcag gcaatgaatt acttttgcaa gccatcgcat tctcttatgt tattaatgag
      901 ttatgctgat ttgttaagca gttttatcac gcttgaaatg gcgtcccgcc ccgacaggtg
      961 aatcgtcggg gctgattttt tcttattatt gcagcagaaa cttctcgagg aactgtcggg
     1021 tgcgaggctg ctggggatcg gcaaataacg cttttgctgc cccctgctcg actatccgcc
     1081 cctggtccat aaaaatcgcc cggtccgcaa catcccgggc aaagctcatt tcgtgcgtca
     1141 caatcaccat cgtgcgcttt tcctgcgcca gctggcggat tgtgttcagg acttcgccca
     1201 ccagctctgg atccagcgct gacgttggct cgtcaaacaa aatcacctca ggacgcattg
     1261 ccagcgcacg cgcaatcgct acacgctgct gttgaccgcc agacaaacga cgtggatagc
     1321 tggtttcttt accggccagc ccaactttcg ccagcagctc gcgagcgcgc gccgtggcct
     1381 cttctttcgg ttcgcctttg acgatcaccg gcccttcaat aatgttttcc agcaccgtac
     1441 gatgcggaaa caaattaaag ttctggaaga caaacccgac gtgctgacgc aactggcgaa
     1501 tcagcgattt ttgctgactt aatgaacgtg cagtatcaat agtgatatcg ccaacggtga
     1561 tcgttcccgc ttccggttgt tccagcagat ttatgctgcg tagcaacgtg gttttgccgg
     1621 aaccactcgg accgataatt gccaccactt cgccaggctt tacctcgagg tcgataccgt
     1681 gcagcaccgt ctgaccgtgg aattttttca ccaggttctt aacttcaatg gcactcattt
     1741 gggttctctc tcctggcgat taagttgatt ctcaaaatgg ttctgcaacg tcgataacac
     1801 agtcgccatg atccagtaga tgagcgaagc cgccaggtac atggtgaaca catccagcgt
     1861 gcgcgaggta atcaactgcg cctgacggaa cagctccggc acctggattg tcgcggccag
     1921 cgacgtatct tttaccagac tgataaagct gttcgacagc ggcggcaacg ccacccgcgc
     1981 cgcctgtggc aaaatcgcgc gacgcatggt ctgccacggc gtcataccaa tactggcagc
     2041 ggcttcccac tgacctttat caatagaaga aatggcggcg cgcagcgttt cggcggcata
     2101 ggcggcagtg ttcagcgaca gaccaatcat tgctgacgga atgggatcta attcgatacc
     2161 aaactgcggc aggccgtaat agatcataaa cagttgtgcg atgagcggcg taccacgaaa
     2221 aatagagata taaaaacgcg ccagccagcg cacgggccag attggcgaca ggcgcatcag
     2281 cgcgagaata aacccgagta gtaagccaaa aaacatgccg ccgatactga gttgcagggt
     2341 atacccagcc cctttcaaca ggaacggcaa ggaatcaata accagttgta tactttcttg
     2401 catgagcgtt cccggagcta aacgtgggga tgataggcga acagcgcagg cgcgccgccg
     2461 gtatgaataa acagaatcgg cccttcatct ttgaagcgtt tctgactgat accgtcaatc
     2521 agccccgcca tcgcttttcc ggtatacaca ggatcaagca gaatgccttc cagacgcgcc
     2581 agcaatttca ctgcttccat gccttcgtcg ttcggcacgc cgtagccagg tgcaaaatag
     2641 tcatcccaga gtaaaatttc cgctgatgcg gtcagctcca gttctttcgc aatcgcctgt
     2701 tgtaggttaa ccactttcgg caattgatcg gcaacggaac gcgacacggt cacgccaatc
     2761 agttcgcttt caggcatcag gtgttccagc ccaacagcca atccggcgtg agttccggca
     2821 ctgcccgatg cgaccaccac cgacgaaata ttaaccgccc cttcacactg ttgcgcgatt
     2881 tccagcgcac tctccacata acccagcgcg cccagagcat tagaaccgcc aaccggaatg
     2941 acatacgggc gaaagccttg tgcttcgact cgcgtcgcca gctcttccag ttgggcattg
     3001 ggatcggtca gtgcgtcgca catttcaatc tgggtattga acagatccag caacaaacga
     3061 ttgccgttgg ttaaatagtt ttctgcggtt gtgccaatag gattttccag cagcgccacg
     3121 cagtgcaggc cgagtttcgc cgcaactgcg gcagtctgcc gcacatggtt agactggatc
     3181 gcgccggcag taatcagcgt atcggcacct tcgcgcaggg catctgccgc gagaaattcc
     3241 agcttacgta atttattgcc gcccattgcc atgggtgtga cgtcatcccg tttgatgaaa
     3301 atttcccgtc caagataatc agaaaagcgc ggcagatatt cgagcggcgt tggcgcgccg
     3361 ataaactcca gccgtggaaa acgggttaaa ttatgcagtg gcataatagc ctccgatgtg
     3421 tgttgttgtg attttcttat tatgcacgct gaaaacgcgt aaataaaaaa ggcgctagtg
     3481 aaagcgccct tttttgtcat tatgctgatt atttggtcac atcagcacca aaccattttt
     3541 cggaaagggc ttgcagagtg ccatcttttt gcatttccgc aattgcatcg ttcactgctt
     3601 tcagcaggtc ttcatttcct ttacgcagcg ccacgccaga ctcctgacgg gagaatgctt
     3661 caccggttac tgccagcgta tcgttggttt tcttcaccag atccagcgcc gccagacggt
     3721 caacgaggat cgcatcgata cggcctacgc gcagatcctg atatttggtc gggtcatcat
     3781 cataggtacg cacatcgacg ccctgaacat tctgccgcag ccactcttca tagttggtgc
     3841 ccagaccgac acccactttt ttgcctttca gatcagcagc cgttttaatg gtgccttcgt
     3901 tacctttttt caccagcgcc tgaataccag aaatggtgta cggggtagag aaatcgtatt
     3961 ttttcttgcg ctcatcagaa atggtgacct gattaatcac cacatcaata cgtttagagt
     4021 ccagcgacgc cagcataccg tcccatttgg tcggttttag tgacgcctca acgccaagat
     4081 gttttgccag ctgttgggca aattctactt caaaaccggt taatttgccg tcatccccct
     4141 gaaaactgaa cggcggataa gttccttcca gccctaccag tagcgtaccg cgctctttga
     4201 ctttattaag cagaccttca tctgcaaaac ttttaacgct catgcccgca accagcgcca
     4261 cggccatcac acccatcaat gcctgacgtc ccagatgtgc taatttcata ttcaccccga
     4321 atgttgttat gtctgtttgc agtgtagagc cattgtttgt aaacacaaaa acaactccgc
     4381 tacatcttat tcttatttaa tatatatcag aagcaggcag gctggaggat ttctgcacaa
     4441 gtccgctaca cgtttgacgc tgatagtgtt gatacttccg taatgcgatg cggtaattgt
     4501 tggtgctggt ggtgggcagc cacggggcga ggatttcatc aaggaaaccg tcctgcagcg
     4561 gatcgaggga aatattttgc tcgtgtagat gattccccaa acggcgcaaa cgaacgacat
     4621 attcacgcac cgtacctggg ctcatttcag tttgctcaaa aagaaattgc ttaaagccga
     4681 taatatcgaa aaaatcactc tgcgttttgc aatgtaaatc accgcaaaat cggcacaatg
     4741 ccgcccatga tttttgttcc gtttgccagc cattttcatc aagcagcgcg tccaggcggg
     4801 aaatctcgat tttattcact attttgccgt cgcgaacgag ggtaatgcga tcgagtaatt
     4861 tacggcaatg cgcgcaatga gtctggctgt gtttaaagtc tttaagatag cggcttaatg
     4921 gccgtctttt caggtgctgc accatcatta agaactcctg gtagtcaaaa ttaaagtgcg
     4981 gcatttactg acgttataac ttacccagtt tagtgcgtaa ccgtttaatg gcctggctgt
     5041 gtaactgact gacccgcgat tccccgacct ccagcaccgc gccaatctct ttgagattca
     5101 gctcttcctg gtaatagagg gttaatacca gtttttcgcg ctccggcaac gtttcgatag
     5161 cttccatcac ccgctggcgc agattactgt ccagcagttg ttgtagcggg ttttctcgct
     5221 gatgatcatc agtaaccagt tcgatgctat cgccgtgctc ttcgcgccac tcatcgtagg
     5281 agaagagctg gctgttattg gtgtcgagca acatttggcg ataatcggca atatcgatcc
     5341 ctaaacgttc cgctacctca gtttccgtgg cgttgcggcc aagttcctgc tccagttgcc
     5401 ctattgcctg tgccacttca cgcgcgttgc gtcgcacgct gcgcggcacc cagtcacggc
     5461 tgcgaagttc atccagcata gcgccacgga tacgctgcac tgcgtaagtt gtaaatgccg
     5521 ttccttgtag ggcgtcatag cgttcgacgg cattaagtaa cccaatgccg cccgcctgta
     5581 gcagatcgtc aagttccacg ctcgcgggca gtcgaacctg caggcgcaat gcttcgtgac
     5641 gcaccagcgg gacataacgc tgccacagcg agtgtttatc cattacacct tcagcggtat
     5701 agagtgaatt cacgataaac agccctgcgt tatatgagtt atcggcatga ttatccgttt
     5761 ctgcagggtt tttaatcgga cgattagtgg gtgaaatgag gggttatttg ggggttatcg
     5821 gtaaattgcg ggcagaaaaa accccgccgt tggcggggaa gcacgttgct gacaaattac
     5881 cattcatgtt gccggatgcg gcgtaaacgc cttatccggc ctacaaaaat gtgcaaattc
     5941 aataaattgc aattcccctt gtaggcctga taagcgcaga gcatcgggca atttggcgtt
     6001 gccgtcagtc tcagttaatc aggttacggc gattaaccct gcagcagaga cagaacctgc
     6061 tgcggtacct ggttggcttt tgccagcacg gagttaccgg cctgctggat aatctgcgct
     6121 ttcgacatgt tggacacttc ggtcgcatag tcagcgtcct gaatacggga ctgcgcttca
     6181 gacaggttgg tagtggtgtt gttcaggttg gcaatggcag aatccagacg gttctgaacg
     6241 gcaccgagag aagagcggaa tttatcaaca gatgcaattg catcatcaag agccttaagc
     6301 gggtcagctg ttaaattgct tggcgcggtt gtagatgcac caatagataa aacaccagca
     6361 tcactgatat tagcggcatt gaaagttgat tgattagttg ttacatcttt ggtctgaatg
     6421 atataagcat cattgccgct tttatcttta tacacgacaa gcgattggtt ggctttaagt
     6481 gcagaagcat ccaattttac atcgcggcca acagtagtta cttccgtcgc tgcagtagga
     6541 gtagttccac tttcatttgt agagttgaag ttaatttcac ccttactagt atctacttcg
     6601 gcatcgtagt acttactact tttagtgtca tttacatagt acttaccgtc tttctcaact
     6661 aattttaggg tacctaacga tcctgaagct ttatctttaa agtcgccagc acctactgcc
     6721 acttgcttat tgatggtggc cccatcttta acactggtgc ccaagtttgt agcatcaaaa
     6781 ctggagaggt ttagtgtaga tgaatcgatc tttttcagat caatagtgat agtctgtcca
     6841 tcatttgccc caacctgaat gttcattttc ccatctttag ccaaaacatt cacgccgtta
     6901 aattgagtct gacttgaaac acgatcaatc tcttccaggc gagatttgat ttcgtcctgg
     6961 atagaagaca ggtcagactc agagttagta ccggtggtcg cctgaacagt cagctcacgc
     7021 acacgctgta agttgttgtt aatttcggac agcgcgcctt cggtggtctg cgcaacagaa
     7081 ataccgtcgt tggcgttacg tgcagcctga gtcaggcctt taatgttaga agtaaaacgg
     7141 ttagcaatcg cctgacccgc ggcgtcatcc ttcgcgctgt taatacgcaa gccagaagac
     7201 agacgctcga tagaactcga cagcgcagac tggttcttgt tgatattatt ttgagtgatc
     7261 agcgagaggc tgttggtatt aatgacttgt gccatgattc gttatcctat attgcaagtc
     7321 gttgattacg ttttgggttt ccacccgtcg gctcaatcgc cgtcaaccct gttatcgtct
     7381 gtcgtaaaac aacctttaga atttttttca caaacagcca ttttttgtta gtcgacgaaa
     7441 tactcttttc tctgcccctt attcccgcta ttaaaaaaaa caattaaacg taaactttgc
     7501 gcaattcagg ccgataaccc cggtattcgt tttacgtgtc gaaagataaa aggaaatcgc
     7561 atggcaagta tttcatcgct gggagtcggg tcaggcctgg atttaagttc aatcctagat
     7621 agcctcaccg ccgcgcaaaa agcgacgcta acccctattt caaatcagca atcgtcgttt
     7681 accgctaaac ttagcgccta cggtacgctg aaaagcgcgc tgacgacttt ccagaccgcc
     7741 aatactgcat tgtctaaagc cgatcttttt tccgccacca gcaccaccag cagcaccacc
     7801 gcgttcagtg ccaccaccgc gggtaacgcc atcgccggga aatacaccat cagcgtcacc
     7861 catctggcgc aggcgcaaac cctgaccacg cgcaccacca gagatgatac aaaaacggcg
     7921 atcgccacca gcgacagcaa actcaccatt caacaaggcg gcgacaaaga tccgatttcc
     7981 attgatatca gcgcggctaa ctcgtcttta agcgggatcc gtgatgccat caacaacgca
     8041 aaagcaggcg taagcgcaag catcattaac gtgggtaacg gtgaatatcg tctgtcagtc
     8101 acatcaaatg acaccggcct tgacaatgcg atgacactct cggtcagcgg tgatgatgcg
     8161 ctacaaagtt ttatgggcta tgacgccagt gccagcagca acggcatgga ggtctcggtc
     8221 gccgcccaga atgcacagct gacggtcaat aacgtcgcca ttgagaacag cagcaacacc
     8281 atcagcgacg cgctggaaaa catcaccctg aacctgaacg atgtcaccac aggcaaccag
     8341 acgctgacca tcactcagga cacctccaaa gcgcaaacgg cgattaaaga ctggatgaat
     8401 gcctataact cgctaataga taccttcagc agcctgacca aatacaccgc cgtagatgcg
     8461 ggagctgata gccagagttc tagcaatggc gcactgctcg gcgactccac gttgcggacg
     8521 attcagacgc agttgaagtc gatgctgagt aataccgtca gttcttccaa ctataaaacg
     8581 ctggcgcaga ttggtatcac gaccgatccc agcgatggca aactggaact ggatgccgac
     8641 aaactcaccg ctgcactgaa aaaagatgcc agcggcgtag gtgcattgat tgttggcgat
     8701 ggtaaaaaaa ccggcatcac gaccaccatc ggcagcaacc tgaccagttg gctttcgaca
     8761 acgggcatta ttaaagccgc taccgatggc gttagtaaga ccctgaataa attaactaaa
     8821 gactacaacg ccgccagcga tcgcattgat gcgcaggtcg cgcgctataa agaacaattt
     8881 acccaactgg acgttttaat gacctcgtta aacagcacca gcagctactt aacgcagcag
     8941 ttcgaaaaca acagtaattc caagtaagca atattcatcg ggagacaggt catgtacgcg
     9001 gcaaaaggca cccaggccta tgcacaaatt ggcgtcgaaa gcgccgtaat gagcgccagc
     9061 cagcagcagc tggtcaccat gctatttgat ggagtgctga gcgcactggt tagagcacgc
     9121 ctgtttatgc aggacaacaa tcagcaaggc aaaggcgtct ctttgtcaaa agcgatcaac
     9181 atcattgaga acggactgcg ggtgagtctt gatgaagaga gcaaagacga actaacccaa
     9241 aacttgattg ctctttatag ctatatggtc aggcgcttgc tgcaagccaa tttacgcaac
     9301 gatgtctccg cagtcgaaga agtggaagca ttaatgcgca atattgccga tgcctggaaa
     9361 gagtctttac tcaccccttc tttgattcag gacccagtct gatgaaccac gcaccgcatt
     9421 tgtatttcgc ctggcaacaa ctcgtcgaaa aaagccagct catgttacgc ctggcaacag
     9481 aagaacaatg ggacgaactc atcgccagcg agatggcgta tgtgaatgcg gtgcaggaga
     9541 ttgcacatct gactgaagag attgacccgt ccaccacgat gcaggagcag ctccgcccga
     9601 tgctgcgcct gattctcgac aacgaaagca aggtaaagca gttattacag attcggatgg
     9661 atgaactggc gaaactggtc ggtcagtcat cggtgcaaaa atcggtgtta agtgcctatg
     9721 gcgatcaggg cggctttgtg ctggctccgc aagataactt atcgtgaatc ttaacgagct
     9781 aatgtctcgc gaataatccg attacggcta cgcttcaaat gttccccttg aatggagtcg
     9841 aagaatgcgt aatcccacgc tgttacaatg ttttcactgg tattacccgg aaggcggtaa
     9901 gctctggcct gaactggccg agcgcgccga cggttttaat gatattggta tcaatatggt
     9961 ctggttgccg cccgcctata aaggcgcatc gggcgggtat tcggtcggct acgactccta
    10021 tgatttgttt gatttaggcg agtttgatca gaaaggcagc atccctacta aatatggtga
    10081 taaagcacaa ctgctggccg ccattgacgc cctgaaacgt aatgacattg cggtgctgct
    10141 ggacgtggta gtcaaccaca aaatgggcgc ggatgaaaaa gaagctattc gcgtgcagcg
    10201 tgtaaatgct gatgaccgta cgcaaattga cgaagaaatc attgagtgtg aaggctggac
    10261 gcgttacacc ttccccgctc gtgccgggca atactcgcag tttatctggg atttcaaatg
    10321 ttttagcggt atcgaccata tcgaaaaccc tgatgaagat ggcattttta aaattgttaa
    10381 cgactatacc ggagaaggct ggaacgatca ggttgatgat gaactcggta atttcgatta
    10441 tctgatgggg gagaatatcg attttcgcaa tcatgccgtg acggaagaga ttaaatactg
    10501 ggcgcgctgg gtgatggaac aaacgcaatg cgacggcttt cgtcttgatg cggtcaaaca
    10561 tattccggca tggttttata aagagtggat cgaacacgta caggaagttg cgccaaagcc
    10621 gttgtttatt gtggctgaat actggtcgca tgaagtcgat aaactgcaaa cgtatattga
    10681 tcaggtggaa ggcaaaacca tgctgtttga tgcgccgctg cagatgaaat tccatgaagc
    10741 atcgcgcatg ggtcgcgact acgacatgac gcagatcttc actgggacgc tggtggaagc
    10801 cgatcctttt cacgccgtaa ccctcgttgc caaccacgac acccaaccgt tgcaagccct
    10861 cgaagccccc gtcgaaccgt ggtttaaacc gctggcgtat gccttaattt tgttgcggga
    10921 aaatggcgtt ccttcggtgt tctatccgga cctctacggt gcacattacg aagatgtcgg
    10981 tggtgacggg catacctatc cgatagatat gccaataatc gaacagcttg atgagttaat
    11041 tctcgcccgt cagcgtttcg cccacggtgt acagacgtta tttttcgacc atccgaactg
    11101 cattgccttt agccgcagtg gcaccgacga atatcccggc tgcgtggtgg tcatgtcgaa
    11161 cggagatgat ggcgaaaaaa ccattcatct gggagagaat tacggcaata aaacctggcg
    11221 tgattttctg gggaaccggc aagagagcgt agtgacagac gaaaacggcg aagcgacctt
    11281 cttttgcaac ggcggcagcg tcagcgtgtg ggttatcgaa gaggtgattt aaatccatcc
    11341 ccggcggcaa gccggggaga tttcattacg gcagtggcgt cggtaacggc gctttatcca
    11401 gcgcggcggc acactctgcc gtcgggcgat ccacacgctc catcgtcata ccatcgtact
    11461 caatggtgtt accgtcacgc tcaacctcgt acagctcacg ttttacggta acgttagtga
    11521 gatcatcaga catcaatgtc aacttacccg gcacggcaat cacccgctgc cactgacggc
    11581 aatccagggt atcgccctct ttagtgacaa tgaggctgcc tatcgcttcc ggactgacca
    11641 acgcacgttg cggccctttg gtctgccagt agcccgccag ccagtccggc gcgggggttt
    11701 tcacgacatt gttatagttt tcgacttcgg cacagcccgc cagcaacatg agcgcacctg
    11761 caattgcgag ttttttcatc attcgtcctg catgagaaga aaagaggatt gtggcattaa
    11821 agccctgatg tcgccagcct ttccaggttc agagagaaat ttgatctaac cattattttt
    11881 gtgaattatt accccgaaaa taaatttgca tggtgtatga ttcgcgactc ttgtttcaaa
    11941 ccttctgagt tcagaggcta cattcatgtc atggcagcaa ttcaaacacg cctggttgat
    12001 taaattctgg gcgcccatcc ccgcggtcat cgcggcgggt attctctcca cttactattt
    12061 tggcatcact ggcacctttt gggctgtcac aggtgaattt acccgttggg gcggtcagct
    12121 cctgcagttg ttcggcgtcc atgctgaaga gtggggttat tttaaaatta tccatctgga
    12181 aggatcgcca ttaacccgca tcgacggaat gatgatcctc ggtatgtttg gcggctgttt
    12241 tgccgcagcg ctgtgggcca acaatgtcaa actgcgcatg ccgcgcagcc gtatccgcat
    12301 tatgcaggcc atcattggcg gtattatcgc cggttttggc gcacgtctgg caatgggctg
    12361 taacctggcg gcgttcttta ccggaattcc acagttctcg ctgcacgcct ggttctttgc
    12421 catcgccact gccattggtt catggtttgg cgcgcgcttt acccttctgc ccatcttccg
    12481 tattcccgtg aaaatgcaga aagtttctgc tgcctcaccg ttgacgcaaa aaccggatca
    12541 ggcgcggcgt cgttttcgtc tcgggatgct ggtctttttc ggcctgctgg gctgggcgct
    12601 gctgacggcg atgaaccagc ccaaactggg gctggcaatg ctgtttggcg tcggctttgg
    12661 tttactgatt gaacgtgcgc aaatctgctt tacttcggcg ttccgcgata tgtggatcac
    12721 cggacgtacc catatggcga aagcaatcat tatcggtatg gcggtaagtg ccatcgggat
    12781 cttcagttac gtacagttag gcgttgaacc caaaatcatg tgggcgggac caaacgcggt
    12841 aattggtggt ttactgtttg gttttggcat cgtgctggca ggcggctgcg aaaccggctg
    12901 gatgtaccgc gcggtagaag gccaggtgca ctactggtgg gtcggtctgg gcaacgtgat
    12961 cggctcaacg attctggcgt actactggga tgatttcgct ccggcgctgg ccaccgactg
    13021 ggacaaaatc aacctgctga aaacctttgg cccgatgggc ggcctgctgg tgacatattt
    13081 gctgttgttt gctgctctaa tgttgattat tggctgggaa aaacgcttct tccgccgtgc
    13141 ggcaccgcag actgctaagg agatcgcatg aaaaatatcg ttcctgatta ccgtcttgat
    13201 atggtgggtg aaccctgccc ttatccggca gtcgcaaccc ttgaggcgat gccgcagtta
    13261 aaaaaagggg agatcctgga agtggtgagc gactgtccgc agtcgatcaa taatattcca
    13321 ctggatgcgc gtaatcacgg ctatacggtg ctggatattc agcaagacgg gccgaccatt
    13381 cgttatttaa ttcagaagta atccctcatt cccgctgtgg cccacagcgg gaatatcgtt
    13441 gcctctctat cacatagatt taacccgccc cctctcctat tcttttcagt gtgacctcag
    13501 gaggtttcta tgtgtggacg ctttgcccaa tcccaaacgc gtgaagatta ccttgcgctt
    13561 ctcgcggaag atattgaacg cgatattccc tacgatcccg aacctattgg cagatacaac
    13621 gtcgcgccgg gaaccaaagt ccttctgctc agtgaacgtg atgaacacct tcatctggat
    13681 ccggttttct ggggatatgc tcccggatgg tgggataaac cgccgctgat taacgcccgc
    13741 gtagaaactg ccgcaaccag tcacatgttt aaaccgctct ggcaacatgg tcgggcaatc
    13801 tgttttgccg atggctggtt tgagtggaaa aaagaaggcg acaaaaagca gccttatttt
    13861 atctatcgtg ctgatggaca agctgttttt atagccgcga taggtagcac accgtttgag
    13921 cgtggtgacg aagccggaag aagtttttgt aagcccgctc agggtctttc agtgactgtt
    13981 gcaatggctg tgagggcgaa tctttaagcc attgcgtttc agtggcattt ttccactcaa
    14041 ccaaccagga agccattttc ccgtaaggga tgtatttatt accggcctca tgattctcat
    14101 tctgaagcgc cagagcacga ttgaaaacga aacgacatgc gcctgcgaag cgcctcattt
    14161 cacgctcctg ttgaccacct ggtcttaacc ggaatttgaa tgcctgtagt cgtttcatgg
    14221 gccaaatcat actttggcct atgaaaaaag aaaccgatat ccgacgcgga aggcattgtg
    14281 ttttcctgaa gcatgttcac ctagtcttcg ttactaaata ccgacgtcag atttttgacc
    14341 atgacgcgac agaaaaacta cgcacttact tttcaaatgt atgtgctgat tttgaagctg
    14401 aacgggttga aatggatggc ggaccagatc acgtccattt gttaattaac tatcctccca
    14461 aactggcgat atccagtctg gtaaacagcc tcaaaggcgt atcgagtagg ttactgcgac
    14521 gagatcgacc agatattgca gtcaggtatt acgacaaagg cgttttgtgg agtcctggct
    14581 attttgtcag tagctgcatc ttaacgtatc aactagattt aataacaacg atatccgcac
    14641 ctaaccggat atctaatgtc ataagcatcc ctttaattat cccctcaacc tcttgtaact
    14701 ttcccactct tgagctccac atagtccaaa cgccggatgc aaaaaaatca cacgtgcatt
    14761 tctgaaattg tgatggagga agatagtatc aattatatgt gcttagaaac gtccccgatt
    14821 agggaaggtg cgaacaagtt cctgatatga gatcatcata ttcatccgga gcgcatccca
    14881 gagggacatc atgagccatc aactcacctt cgccgatagt gaattcagca ctaagcgccg
    14941 tcagacccga aaagagattt tcctctcccg catggagcag attctgccat ggcaaaacat
    15001 ggtggaagtc atcgagccgt tttatcccaa ggcgggcaat ggccgacggc cctatccgct
    15061 ggagaccatg ctgcgtattc actgcatgca gcattggtac aacctgagcg acggtgccat
    15121 ggaagatgcc ctgtacgaaa tcgcctccat gcgcctgttt gcccgattat ccctggatag
    15181 cgccctgccg gatcgcacca ccatcatgaa tttccgccac ctgctcgagc agcatcaact
    15241 ggcccgtcaa ttgttcaaga ccatcaatcg ctggctggcc gaagcaggcg tcatgatgac
    15301 ccaaggcact ttggtggatg ccaccatcat tgaggcaccc agctctacca agaacaaaga
    15361 gcagcaacgc gatccggaga tgcatcagac caagaaaggc aatcagtggc actttggcat
    15421 gaaggcccac attggtgtcg atgccaagag tggcctgacc cacagcctag tcaccaccgc
    15481 ggccaacgag catgacctca atcagctggg taatctgctt catggagagg agcaatttgt
    15541 ctcagccgat gccggctacc aaggagcgcc acagcgcgag gagctggccg aggtggatgt
    15601 ggactggctg atcgccgagc gtcccggcaa ggtaaaaacc ttgaagcagc atccgcgcaa
    15661 gaacaaaacg gccatcaaca tcgaatacat gaaagccagc atccgtgcca gggtggagca
    15721 cccgtttcgc atcatcaagc ggcagttcgg cttcgtgaaa gccagataca aggggctgct
    15781 gaaaaacgat aaccaactgg cgatgttatt caccctggcc aacctgtttc gggtggacca
    15841 aatgatacgt cagtgggaga gatctcagta aaaaccggaa ataacgccag aaatggtgga
    15901 aaaaatagcc taaataggct gattcgatgt gtttgcggga aaaaaatcgg cccagatccg
    15961 agaaatttta atcagcgagt cagcttggga agaaatgacc tgcttattcg caccttccct
    16021 aacagtcagc acatcaagca catcattaat caacatccca atacgttatt tatcgttttt
    16081 atggcaattg ccaatgttca ttttgatgaa tatctattgg tcagaaaaaa tttattgatc
    16141 agttctaaat cgattaaacc ggaatctctc gacgatatcc ttggcgatat tctgaaaaaa
    16201 gagacaacga taacctcgtt tttaaatatg ccgacgttat cattgagccg aaccgaatcg
    16261 agtatgttgc gaatgtggat ggcaggtcag ggaaccattc aaatctctga ccaaatgaat
    16321 atcaaagcca agaccgtttc atcgcataaa ggtaatatta aacgtaagat caaaacgcat
    16381 aataaacagg ttatctacca tgtcgtccga ctgacggata atgtgactaa tggtattttt
    16441 gtcaacatgc gctaacacat tctgactggt ggtttcccac cagtcaggct gaataagatt
    16501 actctgcttt ctccacaaag ataccgtcct gatgccctgc ttcattaaaa aaccagatgc
    16561 cgagcgggta gtcttccagc gaaaccaggt acattgtgcc ttcactaaac tcctcaactg
    16621 ccagtaccac gccaggacga cgcggaccgc catccgtttt gactgttacc cgatcattca
    16681 ccttcatcgt tttcctcctg tgcctttgtg ccagtgtaga acaatttcgt ttttctggca
    16741 gcgccaggcg cgcgcgagtg ctgattttct cgacggtcta tacttaagtg atgccaggcg
    16801 gacttaacga ctggcggcaa caacagagta acggttgcga ggaaagatga tgaaaaccgc
    16861 aaaagagtac agcgataccg caaaacgtga ggtcagcgtc gatgtcgatg ccctgctggc
    16921 ggcgatcaat gaaattagcg aaagcgaagt tcatcgcagc cagaacgatt ctgaacacgt
    16981 tagcgtcgat ggacgtgaat atcatacatg gcgtgaattg gcggatgcct tcgaactgga
    17041 tattcatgac ttcagcgtct ctgaagtgaa tcgttgaatg cacaataaaa aaatcccgac
    17101 cctgaggggg tcgggatgaa acttgcttaa gcaagaagca cttaaaaaat tcgttacacc
    17161 aggaaatctg atgtgttcat caccttatcc gcaatttttt tcgctgacaa gaaaatattc
    17221 gtgatatgaa tgattaacgc tacttatgaa tagaaatgtg acgcgcgtca ccccttggtg
    17281 gctctggcgt caacgggatc gctcccgaaa aaatcatctt tgataatttg tgctgttttg
    17341 agaatcatcc tggtaagggg agtactgcgc aaccatgctt tcaattcaac aaccactact
    17401 ggtttttagc gatcttgatg gcaccctgct ggacagtcat agttatgact ggcaaccagc
    17461 tgccccctgg ctcagccgtt tacgcggagc gaatgttccc gtcattctct gtagcagtaa
    17521 gacatcagcg gaaatgctgt acttgcaaaa aacgttgggg ctacaaggtt taccgctgat
    17581 tgccgaaaat ggcgcagtga tccagctagc tgagcaatgg caggatatag acggttttcc
    17641 acgcatcatc tcaggtatta cccatggcga aatcatccag gtattaaata cgctgcgtga
    17701 gaaagagcat tttaaattca caacttttga tgacgtcgac gatgaaacca tcgccgaatg
    17761 gacgggatta aaccgtagcc aggcggcact gacgcagtta catgaggcat ctgtaacgct
    17821 tatctggcgc gacagtgacg agcggatggc gcaatttacc gcccgtctga acgagctggg
    17881 cttgcagttt atgcaggggg cgcgcttctg gcacgtactg gatgcctctg ccggaaaaga
    17941 tcaggccgca aactggatca tcgcgaccta tcaacaatcg ttaggcaaac gaccaaccac
    18001 gcttggtctg ggcgatgggc caaacgatgc gcccttactg gaggtaatgg attacgcggt
    18061 gattgtgaaa gggctaaatc gtcaaggggt gcatctgcat gatgaggatc cggcccgcgt
    18121 ctggcgaacg cagcgtgaag gaccggaagg ctggcgtgaa gggctggacc attttttctc
    18181 cgcccgttaa gcgttatcgc tcgcgaatac ccgattgcgc ccggcctatt tagcgagata
    18241 aagtcgacgg tcggccagcg actggagttg ttcaaaatca taatcaccgg tttcctcgct
    18301 gctgcttacc cccagcgagg cactgatgcg tatcgtcgta ctcttggcga tcaacatctc
    18361 tttttcattt agcttcaggc gaatacgttc tgcaacctcc gcagcctgcg tcagactcgc
    18421 gcctggcaga atcacacaaa actcctcgcc accgacccgc ccggcaacgt cctgcgcacg
    18481 caaggaactg ctaattaatc cggcagcatg agaaagaaca cggtcgcccg cctgatggcc
    18541 aaagcggtca ttaatcgctt taaaatggtc aaggtcgacc tgaatgacag aaaaaggatg
    18601 ttggtgcgtc tgacacaatt tagcgagcga acgggctttt tcgaacagtg cgccacggtt
    18661 atataaacgc gttaaggtgt cgtgccacgc ctgccactgc aacgagcttt gcaaaacata
    18721 catgttgctg gccatccggc gaatcacata ccaggagatg agtaacatgg tggtaaagag
    18781 cgcccacagc agagttaatg caatgctgat actgccgaaa tcaccacgca cgccttcgct
    18841 tagcgtatgg acgcgcacca gcacaccgtc gaaatggtcc agacgttccc agctaacata
    18901 gcgactgttc atacgaatgc cgccccgcgt gtcatgttcc attgcctgcg ccagcaaggc
    18961 cagttcacga gggtcaaaaa tattccctgt tggatggtca ggattggaag aggtcaataa
    19021 tctcagctta ctgtcataga gctgatactc accatcgagg tttttatcga tggcgtttct
    19081 taaaaattgc tgcatggtac gcacgggaat actcatcccc agcacgccat accagtagtt
    19141 ttcactgtct accggaacac tgacggtaac ctgcggttca gtattgctgg cgtgttccgg
    19201 ttgtgaagtg aaccagcgta ccgcgcggtg acgattttct cgttgcgaat ggccgacaaa
    19261 ccagggttgg gtgacatagc cgtaataacg cgttggtaca ttgcgcgtaa ataaggtcgg
    19321 ctgcgtcgaa acgtaaaatc cggcacgcga gacatacatc gcctgttcaa ccatcgacga
    19381 ggagttgtgc gccagtcgca gcaagtaacc aacttccagt gcagcggtaa tttcattgtc
    19441 gaggctttca ttttcgcgag acaggagatt cccctcgctg actaatgcat ccgacacacc
    19501 attgactggc agggtgcgtc gtcggttgag ttcgatttgc caggcgtgct cgtcgcgatg
    19561 ctgttcaaac tcggtaacgg cattacgcag agaggtgaaa tccagtggcg ctacgagagc
    19621 ttcgcgcatg ccattacgca aaaagatcag tttgtcgacg ttatactgca gatgcttatc
    19681 gagcgcgttg gctacgtttt ccagatgatt acgctggctg gagatatagg catcttccag
    19741 caccaccact tcacgccagg tgagcaaggt ggaaaaaagc aataccacga taaagcagag
    19801 attaacgaca tgaccaggcc ccaggcggcg tgcgagtttt ttcaaccagc tctggttttc
    19861 catttttgtc tcgtgctgca ccctgacgac tcccaacctg cttttttatg attctggcat
    19921 aacccggcga taacgtaccg caaaacagcg ataattttat aatggtggca tgacaagacg
    19981 cgactatcat tcattgcagg cattggcaca ccaggccgga tgtgaaccgg cctggtgtta
    20041 atgataccct ttcaaacttc ttccgcagaa cgactcccct cccccggaac aagctcggtt
    20101 tcatgaaaag cttcccgctt gaccccgtaa ccgtcatacc aacgacactc aaccataccg
    20161 ctggagtatc cggtgacaat catccgcggg ccgccctctt taaccgtaac ttcctcacta
    20221 accataaagc tcatactcgc ctcctttttt cgagtgaaac ttgttcacct tagttgaaga
    20281 tggcgaattt tgcataatag cctgtgcgag tattaatgtg cctgaccgcg cattttcgct
    20341 actgctttca ctcccagcac cacgatgccg ccgatgataa acccaagaat cagatttaaa
    20401 acagtcggta atatcatcgc caccactgca ctttgctgcc cggcgaaatg ttcaatggcg
    20461 tgatgcagcg gcgcaatacc atgtaccaca atcccgccgc cgacgaggaa catcgccagc
    20521 gtgccgacaa tcgataacgc tttcatcagc cagggcgcga taatcaataa ccctttaccc
    20581 aatgcctgca tcagcgcgct ggatttttcc gccagccaat accccaggtc atcaatctta
    20641 acaataaccc ctaccagccc gtagacgccc acggtcacta ccagtgcgat gcctgaaagc
    20701 accagcacct gattaagcaa cggcgcttct gccacaatcc ccagcgtgat ggcgacgatt
    20761 tccgcagaca aaataaaatc agtacgaatc gcccctttta ttttgtcctt ttcaaacttc
    20821 agcggatcct gcgccgccag cttctccaga cgctgctgac tctgcgccgg atcttctttg
    20881 tgtttacgcg cctccagcat atgcagcact ttctctaccc cttcaaagca gagaaacgcg
    20941 ccgccaatca tcaacaaagg cgtaatcgcc cacgggataa atgcactgat gatcagcgcc
    21001 agcggtacca gaatcacttt attgatcagc gatcctttcg ccactcccca gaccacggga
    21061 agttcccggt tggcacgcac acctgaaact tgttgtgcat tgagcgataa atcatcccct
    21121 agtacaccgg cggttttctt cgccgccagt ttgcccatca cggagatatc gtccagcagt
    21181 gtggcgatat catcgagcaa cgtcagtaaa ctactcccgg ccaaaagcat tccctctcat
    21241 ttttattgtt gaagggagta agtatgaagc aaaaacggca gctctgatac ttgcttcata
    21301 ggtcaacatt tttttaacaa tcaagtgcaa ttatatctct cgccagcaga atgattttca
    21361 cgtttactat gaaccacctt tttattttca ccgtgaggga ttatgcgttt ccgccagttg
    21421 ttaccgcttt ttggcgcgct gtttgcgttg tatatcattt ggggctcaac ctattttgtc
    21481 attcggattg gcgtggaaag ctggcctccg ttaatgatgg cgggcgttcg attcctggca
    21541 gccggtattt tattgatggc atttttgcta ctgcgcggac acaaactccc cccgctacgt
    21601 ccgctgctca atgccgcgct gattggcctg ttattgctgg ctgtcggtaa tggcatggtg
    21661 acagttgccg aacatcaaaa tgttccatcc ggcatcgccg ccgtagtggt tgcaaccgtg
    21721 cccctcttta ccctgtgctt cagccgcctg tttggcatta aaacgcgcaa actggaatgg
    21781 gtgggtatcg ccattgggct tgccggaatc atcatgctca atagcggtgg aaatttaagc
    21841 ggcaatccgt ggggtgcgat tctgatttta atcggctcga ttagctgggc gtttggctcg
    21901 gtttatggct cgcgcattac cttacctgta gggatgatgg cgggtgcgat tgagatgctt
    21961 gcggctggcg tggtgttaat gattgcgtcg atgattgcgg gtgaaaaact gacggcgctc
    22021 ccttcccttt caggcttcct tgcggtcggc tatctggcgc tgtttggttc gattatcgcc
    22081 atcaacgctt atatgtattt aatccgtaat gtcagtccag ctctcgccac cagctacgcc
    22141 tacgttaacc cggtggtcgc ggtcttgctg ggtacaggac tgggcggcga aaagctgtcg
    22201 aagattgaat ggctggcgct cggcgtaatt gtattcgcgg tggtactggt cacgttggga
    22261 aaatatctct ttccggcaaa acccgtagtt gcgccagtta ttcaggacgc atcaagcgag
    22321 taaatgaatc ccctgcgtgt cgatctgcgc gctggcacct tcgccgcaga tccactcttc
    22381 cagacgctcg ataagcgctt catccgtcag cttctcgcgc ccacgtaacg cacactccca
    22441 gacaatcagt acgcgccagc cgagctcctg caagcgactg atatcgcggc gatcgcgctc
    22501 aacattttta cctatcttct ccagccagaa ctcagttcga gtcgcaggca ctttaaacag
    22561 atagcagtga tgatggtgcc agaagcagcc gtgggtaaat atcacgcaac gatattcatc
    22621 aacgacaaaa tccggacgtc cgggcagact ggcgtcctga acgcgaaatg ccaggccctg
    22681 cccggttaac agactggcga ggcgcttctc tatcgccgta tcacgcgtgg caatcgcgcg
    22741 catatttttg ctgcgagtgg ccttatcgtg aacgtcggcc atgttgtgcc tcttgctgac
    22801 gcaacgccac cgcctgtttg atttttggct caagcagttt tgccaccgcg gcaaagaccg
    22861 gcacgaccac cgagttaccg aactggcgat aggcctgagt gtccgaaacc ggaatgcgga
    22921 atttcgcttc tcccggcgct tcaaaaccca ttaagcgcgc gcattcccga ggcgttaacc
    22981 gacgtggacg atgttgctga ttcagcggat cgtcaaagtc tttttcaccc gtggccatat
    23041 cccatccgcg atcgattaaa atttccgcgc catctttgta ataacgcgca gacagcgtac
    23101 gggtgacgct ttgcggattg ttcggataaa ccattccata accgaagccg ttaccgcgcg
    23161 cctgatgttt tttcgcatat cgatagaggt acttccacag taccggcgtc aggatatatt
    23221 tcgcctcgac catcggatcc agcagctgcg ccagcgtcac tcgctgcgca gggaaacatc
    23281 cgctgatatc acgcagagta aaatcggctt tcagattcag gtcgcgacga aaacccacca
    23341 gcacgatgcg ttcacggtgc tgcggaagga aatgtttacc gtcaatgatt ttcggatcgt
    23401 ccgggccatt atcttctgca tctgccacgt catagcccag ttcatccaac gtctgcatga
    23461 tgatacggaa cgttttcccc tggtcgtggc ttttcaggtt tttgacgttt tcgagcacaa
    23521 aaatcgccgg gcgacgcgcg tcgataatac gcaccacatc gaagaacagc gtgccctggg
    23581 tatcacaggc aaaaccgtgc gctcgtccga gtgagttctt tttcgatacg ccagccagag
    23641 aaaacggctg acaaggaaaa ccggccagta aaacatcgtg ctcaggaata tgttgacgga
    23701 tatgttccgc cgccacgtca tcacctatac cctctttgtg actgagagtg atgtcgcgaa
    23761 tatcttcatt aaagtgatgc accgccgggt cgcaataata gttggcttta taagtgcgta
    23821 cagcatgttt gttccattcg ctggtaaaca cgcactgccc accaatcgat tcaaaaccgc
    23881 gacgaatacc accaatcccg gcaaatagat cgataaagcg aaacgcataa tgcggatgat
    23941 gtgccggtgg aatgggtaac aacgtttgca gatgggcgaa ctctttatca cttaaacggt
    24001 gccatgctga gtcattcgcc agcgcacgtt ttaaaattgc cgcgctccag tgattctcac
    24061 ccacaccatt aagatgcgcc accagcgttt tgacatcata aatttgcagc agttgctcca
    24121 gcattgcctg tgcggcattc ccggtgctgt atgaatcggt tactgatata ttttcctgca
    24181 tagatttaac cggccatctg agatggccga caggttaaca taattaccat catttagggc
    24241 cacgtgctca gccaaccggt gaaaacgtat caatcacctt gtgatcgata ccttcattct
    24301 cccccgccag ctcagcactg agcttcgcca taaactcaac taaaaattgc gcgttgtact
    24361 gcgccagttg tttgcctttt atggtttgca tggtgtgcgg tagcttcagc aacttagtct
    24421 gaaaatgatc cagcgcgtaa cgtttatcat caagtgggcg atgctgcgcg aacggatctt
    24481 cgccatcaaa caatgccacg cccaacgccc ccgaaacggc aaacacacgc gccaggccaa
    24541 tcgcccccag agcttccagc cgatccgcat cctgaacgat tttagcttcc gccgttaaag
    24601 gggcgatttg cgcgctgaaa ctgtgagcgg caatggcatg acaaacggcc tcgattttct
    24661 ccgccggaaa ttgctcgaac tcttcacgga gcaggcgacg cgtctcttct gccgccagga
    24721 ttgaagaacg ctgcctttgc ggatgatttt tcgccaggct cacaatatcg tgaaaataac
    24781 aggcggttaa aatcaccagc atatcgacat cgtcatctgc cgccagcttc tgtgccgtag
    24841 cccagacgcg gcgaaaatga cacacgtcat gggccgcgtc ctggtgctga tgatggtttt
    24901 tcaaccagtt ttcgaactgt gcctgccagt gttgtaagtc catacgcgct ccgttgccaa
    24961 agagtcgcca ccttagcagt ttttattcat agcgtctgct acgtgcggga cgaggtcggg
    25021 tgtaccaggc aatgctgcct aacaatgccc cgaccagagc cataaataaa aatccgacca
    25081 gtgcccctaa ccactttccc gcggtagagc ctaaatcgct ttcaaatccc gacacggggg
    25141 catcggggat ccggctcatc acccagatgt aacgcgccat tgcccagacg aaatagccac
    25201 accatgtata gaaagcccac aaagccagtt tgccaccagg gctgcgagag attctctctt
    25261 ccatctttgt cgaaccgtat tccattttga gataacccgg aaaattcaga cttagtacta
    25321 ttatgtgata aaagtcacat ttttccacat tggatgagcc agtcaagact cactcatttt
    25381 ttgaacaaat agataatttt tgcgcaacgg cagtgaatac aggaaaaatc gttttgagcg
    25441 attttattta tctttgagat cggctttatt aattcattta atcaatatat tagcactgaa
    25501 tacaattata cctttttatt tttctgtgtc atgatgcctc cgttattagc cttttatcgt
    25561 cttgtttata ttttttgggc cggcatgatg ccggcttttt tttatgcctt cattaatgtg
    25621 cgcgtgatca caccagccgt ttggcgcaac aatcattgat accccctatg cttccgctca
    25681 actcataaca tattgatata cattt
//
LOCUS       DACAOP010000063        24787 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.063, whole genome shotgun sequence.
ACCESSION   DACAOP010000063 DACAOP010000000
VERSION     DACAOP010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24787
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.063"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            258..1673
                     /gene="gltX"
                     /locus_tag="IT892_002877"
     CDS             258..1673
                     /gene="gltX"
                     /locus_tag="IT892_002877"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAP3136073.1"
                     /translation="MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDT
                     DLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSK
                     ERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPI
                     EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALK
                     APVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEI
                     FTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDT
                     RNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVR
                     DKLAAITDWTTENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGK
                     TRSIERINKALAFIAERENQQ"
     gene            complement(1724..2116)
                     /locus_tag="IT892_002878"
     CDS             complement(1724..2116)
                     /locus_tag="IT892_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000826498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HAP3136074.1"
                     /translation="MKRLRNKMTTEELAECLGVAKQTVNRWIREKGWKTEKFPGVKGG
                     RARLILVDTQVCEFIQNTPAFHNTPMLLEAEEPLAEYAPGIRTPAYRQIISAIDNMTH
                     SEQEKVAQFLSREGIRHFLARLDIDESE"
     gene            complement(2118..2462)
                     /locus_tag="IT892_002879"
     CDS             complement(2118..2462)
                     /locus_tag="IT892_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708260.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HAP3136075.1"
                     /translation="MTPDELARLTGYSRQTINKWVRKEGWTTSPKPGVQGGKARLVHV
                     NEQVREYIRNAERPEGQGEAPALSGDAPLEVLLVTLAKEMTPVEQKQFTSLLLREGII
                     GLLQRLGIRDSK"
     gene            2698..2773
                     /locus_tag="IT892_002880"
     tRNA            2698..2773
                     /locus_tag="IT892_002880"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2731..2733,aa:Ala,seq:ggc)
     gene            2981..5170
                     /locus_tag="IT892_002881"
     CDS             2981..5170
                     /locus_tag="IT892_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HAP3136076.1"
                     /translation="MFVEHNLIKNIKIFTLAFTLTVVLIQLSRFISPLAIIHSSYIFL
                     AWMPLCVMLSILFIFGWRGVVPVLCGMFCTNLWNFHLSFLQTAVMLGSQTFVVLCACA
                     ILRWQLGTRWRYGLTSRYVWQRLFWLGLVTPIGIKCSMYLVGSFFDFPLKISTFFGDA
                     DAIFTVVDLLSLFTAVLIYNMLFYYLTRMIVSPHFAQILWRRDIAPSLSKEKRAFTLS
                     WLAALSVLLLLMCTPYENDFIAGYLVPVFFIIFTLGVGKLRYPFLNLTWAVSTLCLLN
                     YNQNFLQGVLTEYSLAFILAVLISFSVCLLYMVRIYHRSEWLNRRWHLQALTDPLTLL
                     PNFRALEQAPEQEAGKSFCCLRIDNLEFMSRHYGLMMRVHCIRSIYRTLLPLMQENEK
                     LYQLPGSELLLVLSGPETEGRLQHMVNILNSRQIHWNNTGLDMGYGAAWGRFDGNQET
                     LQPLLGQLSWLAEQSCAHHHVLALDSREEMVSGQTTKQVLLLNTIRTALDQGDLLLYA
                     QPIRNKEGEGYDEILARLKYDGGIMTPDKFLPLIAQFNLSARFDLQVLESLLKWLATH
                     PCDKKGPRFSVNLMPLTLLQKNIAGRIIRLFKRYHISPQAVILEITEEQAFSNAESSM
                     YNIEQLHKFGFRIAIDDFGTGYANYERLKRLQADIIKIDGVFVKDIVTNTLDAMIVRS
                     ITDLAKAKSLSVVAEFVETQQQQALLHKLGVQYLQGYLIGRPQPLAD"
     gene            complement(5221..6423)
                     /gene="nupC"
                     /locus_tag="IT892_002882"
     CDS             complement(5221..6423)
                     /gene="nupC"
                     /locus_tag="IT892_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupC"
                     /protein_id="HAP3136077.1"
                     /translation="MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLA
                     WFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFIS
                     ALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGK
                     ISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVD
                     ASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTG
                     WFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIAST
                     LSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLS
                     ASIAALVL"
     gene            6759..7997
                     /gene="mntH"
                     /locus_tag="IT892_002883"
     CDS             6759..7997
                     /gene="mntH"
                     /locus_tag="IT892_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mn(2+) uptake NRAMP transporter MntH"
                     /protein_id="HAP3136078.1"
                     /translation="MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQA
                     GASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAE
                     IIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
                     LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSS
                     LTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAY
                     LTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLP
                     SFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWV
                     IVVLVVALNIWLLVGTALGL"
     gene            complement(8139..8465)
                     /locus_tag="IT892_002884"
     CDS             complement(8139..8465)
                     /locus_tag="IT892_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HAP3136079.1"
                     /translation="MFRSLFLAAALMAFTPLAANAGEITLLPSIKLQIGDRDHYGNYW
                     DGGHWRDRDYWHRNYEWRKNRWWRHDNGYHRGWDKRKAYERGYREGWRDRDDHRGKGR
                     GHGHRH"
     gene            complement(8580..9836)
                     /locus_tag="IT892_002885"
     CDS             complement(8580..9836)
                     /locus_tag="IT892_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel protein"
                     /protein_id="HAP3136080.1"
                     /translation="MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQR
                     LPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPG
                     LIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALF
                     GTPVAAALIFSQTLNGSSEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQM
                     EMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVLVLGIGGFILGILGVIGG
                     PVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVA
                     LGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVML
                     PAWLLLAGKPMMMVNRPKQQPPHDNV"
     gene            10040..11005
                     /gene="glk"
                     /locus_tag="IT892_002886"
     CDS             10040..11005
                     /gene="glk"
                     /locus_tag="IT892_002886"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HAP3136081.1"
                     /translation="MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAV
                     IRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFT
                     AVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
                     VDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDI
                     TERALADSCTDCRRALSLFCVIMGRFGGNLALTLGTFGGVYIAGGIVPRFLEFFKASG
                     FRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL"
     gene            11224..11550
                     /locus_tag="IT892_002887"
     CDS             11224..11550
                     /locus_tag="IT892_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-like phosphotransferase enzyme IIB
                     component 1"
                     /protein_id="HAP3136082.1"
                     /translation="MSKKLIALCACPMGLAHTFMAAQALEEAAVEAGYEVKIETQGAD
                     GIQNRLTAQDIAEATIIIHSVAVTPEDNERFESRDVYEITLQDAIKNAAGIIKEIEEM
                     IASEQQ"
     gene            11572..12819
                     /locus_tag="IT892_002888"
     CDS             11572..12819
                     /locus_tag="IT892_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HAP3136083.1"
                     /translation="MAIKKRSATVVPGASGAAAAVKNPQASKSSFWGELPQHVMSGIS
                     RMVPTLIMGGVILAFSQLIAYSWLKIPADIGIMDALNSGKFSGFDLSLLKFAWLSQSF
                     GGVLFGFAIPMFAAFVANSIGGKLAFPAGFIGGLMSTQPTQLLNFDPSTMQWATSSPV
                     PSTFIGALIISIVAGYLVKWMNQKIQLPDFLLAFKTTFLLPILSAIFVMLAMYYVITP
                     FGGWINGGIRTVLTAAGEKGALMYAMGIAAATAIDLGGPINKAAGFVAFSFTTDHVLP
                     VTARSIAIVIPPIGLGLATIIDRRLTGKRLFNAQLYPQGKTAMFLAFMGISEGAIPFA
                     LESPITAIPSYMVGAIVGSTAAVWLGAVQWFPESAIWAWPLVTNLGVYMAGIALGAVI
                     TALMVVFLRLMMFRKGKLLIDSL"
     gene            12834..13919
                     /gene="ypdF"
                     /locus_tag="IT892_002889"
     CDS             12834..13919
                     /gene="ypdF"
                     /locus_tag="IT892_002889"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP3136084.1"
                     /translation="MTLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVLISR
                     ESAHILVDSRYYADVEARTQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVCW
                     ETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSE
                     REIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQ
                     GYCSDMTRTLLVNGEGVSAESHPLFDVYQIVLQAQLAAISAIRPGVRCQQVDDAARRV
                     ITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRI
                     EDVVLVTPQGAEVLYAMPKTVLLTGEA"
     gene            13919..14956
                     /gene="ypdE"
                     /locus_tag="IT892_002890"
     CDS             13919..14956
                     /gene="ypdE"
                     /locus_tag="IT892_002890"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP3136085.1"
                     /translation="MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGS
                     VLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRITTR
                     EECKIPGLLDGDRQGNDVSTMRVDIGARSYDEVMQAGIRPGDRVTFDTTFQVLPHQRV
                     MGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGKTATRAVSPDVAI
                     VLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWIETVAAEIGVPLQAD
                     MFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMQQLLSALIQRLT
                     RETVVQLTDFR"
     gene            14981..17476
                     /gene="ptsP"
                     /locus_tag="IT892_002891"
     CDS             14981..17476
                     /gene="ptsP"
                     /locus_tag="IT892_002891"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAP3136086.1"
                     /translation="MLTIQFLCPLPNGIHARPAWELKEQCSQWQSEITFINHRQNAKA
                     DAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLEEYIQVRFIDSDSIQPTQAELTA
                     HPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRAIPASAQDSTRLEHSLA
                     TLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRHLMAEQHQGLGAAIISNMEQ
                     VCAKLSASASDYLRERVSDIRDISEQLLHITWPELKPRNNLVLEKPTILVAEDLTPSQ
                     FLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCG
                     VLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPG
                     AFANGAEGVGLFRTEMLYMDRDSAPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKS
                     IPYLNIPQEENPFLGYRAVRIYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHSLDQI
                     LWVKGEIQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMT
                     QYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTTAHQRGKWVGICGELGGESRYLPLL
                     LGLGLDELSMSSPRIPAVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFTPEED
                     VRPLLALENIFVDQAVSNKEQAIQFLCGNLGVNGRTEHPFELEEDVWQREEIVTTGVG
                     FGVAIPHTKSQWIRHSSISIARLVKPVDWQSEMGEVELVIMLTLGANEGMNHVKVFSQ
                     LARKLVNKNFRQSLFAAQDAQSILTLLETELTF"
     gene            complement(17479..18336)
                     /locus_tag="IT892_002892"
     CDS             complement(17479..18336)
                     /locus_tag="IT892_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP3136087.1"
                     /translation="MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSL
                     CIDFPRLDIVLRGEYGNLLEAKQQRMVEGEMLFIPARAANLPVNNKPVMLLSLVFAPT
                     WLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
                     LHLCRNVVNMPPGNSQPRSDFLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLF
                     AQHGTMRFIEYVRWVRMAKARMILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTP
                     GEYSARFRG"
     gene            complement(18349..19083)
                     /locus_tag="IT892_002893"
     CDS             complement(18349..19083)
                     /locus_tag="IT892_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP3136088.1"
                     /translation="MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQH
                     NRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKP
                     YQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEA
                     HEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYI
                     LRLKDLDFEVPVSRSKVKEFRQLMHL"
     gene            complement(19098..20795)
                     /locus_tag="IT892_002894"
     CDS             complement(19098..20795)
                     /locus_tag="IT892_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP3136089.1"
                     /translation="MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKE
                     LLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRY
                     LIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
                     PTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLP
                     LFRHVNSESLRKVCEIIRDDIHADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQ
                     AMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAV
                     GLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTAR
                     QLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNC
                     CIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERV
                     EANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL"
     gene            21172..22410
                     /gene="alaC"
                     /locus_tag="IT892_002895"
     CDS             21172..22410
                     /gene="alaC"
                     /locus_tag="IT892_002895"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HAP3136090.1"
                     /translation="MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMG
                     NPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVEIDPESEAI
                     VTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
                     LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY
                     DGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYG
                     TFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKI
                     PEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKA
                     MFRADGLLPASSKHIHENAE"
     gene            complement(22475..22546)
                     /gene="ypdK"
                     /locus_tag="IT892_002896"
     CDS             complement(22475..22546)
                     /gene="ypdK"
                     /locus_tag="IT892_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_077777854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YpdK"
                     /protein_id="HAP3136091.1"
                     /translation="MKYFFMGISFMVIVWAGTFALMI"
     gene            complement(22902..23822)
                     /gene="lpxP"
                     /locus_tag="IT892_002897"
     CDS             complement(22902..23822)
                     /gene="lpxP"
                     /locus_tag="IT892_002897"
                     /EC_number="2.3.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311285.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) palmitoleoyltransferase"
                     /protein_id="HAP3136092.1"
                     /translation="MFPKCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRI
                     GAMARPFLKRRESIARKNLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDS
                     RVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQL
                     MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGRKGSSFAPFFAVEN
                     VATTNGTYVLSRLSGAAMLTVTMVRKADYSGYRLYITPEMEGYPADENQAAAYMNKII
                     EKEIMRAPEQYLWIHRRFKTRPVGESSLYI"
     gene            24175..24417
                     /locus_tag="IT892_002898"
     CDS             24175..24417
                     /locus_tag="IT892_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdY family protein"
                     /protein_id="HAP3136093.1"
                     /translation="MIYLWMFLALCIVCVSGYIGQVLNVVSAVSSFFGMVILAALIYY
                     FTMWLTGGNELVTGIFMFLAPACGLMIRFMVGYGRR"
     gene            complement(24494..24769)
                     /locus_tag="IT892_002899"
     CDS             complement(24494..24769)
                     /locus_tag="IT892_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136094.1"
                     /translation="MKVNLMLFSLFLLVSIMACNVFAFSISGGGSETSYKETEKKSVM
                     TTTHSTKLQPSQAILFKMREDAPPLNLTEDITPPFPTKANYLIHPVR"
BASE COUNT         5966 a         6119 c         6547 g         6155 t
ORIGIN      
        1 cgctgtgtgg agtcgcatta tagggagagt tcaaaatgag tcaacgcatt ttctaaagaa
       61 attgttcgtt cgtcgtaaat ttaagcaaga tgatcgcaaa acagaccgtg ttgcgcaatt
      121 tgtcaacgaa aacaataatg cgtaaggttg caacccgaac tacattgagg aatcaggcgg
      181 gagtgataga atatcgccca ctcaattttt ccaggatttg ccggttgtcg gcatctttct
      241 aaacgtaagg ccatttcatg aaaatcaaaa ctcgcttcgc gccaagccca acaggctatc
      301 tgcacgttgg cggcgcgcgt actgctcttt actcctggct ttttgcacgt aatcacggcg
      361 gtgagttcgt gctgcgtatt gaagacaccg atcttgagcg ttccacgccg gaagctatcg
      421 aagccattat ggatggcatg aactggctga gcctggagtg ggatgaaggt ccgtactacc
      481 agaccaaacg ttttgatcgc tacaacgcgg tgatcgatca gatgctggaa gagggcacag
      541 cttataaatg ctattgctct aaagagcgcc tggaagcgct gcgcgaagag caaatggcga
      601 aaggtgagaa gccgcgttat gacggtcgct gccgccacag ccatgagcat catgctgatg
      661 atgaaccgtg tgttgtacgt tttgctaacc cgcaggaagg ttctgttgtt tttgacgatc
      721 agatccgtgg tccgatcgaa ttcagcaacc aggagctgga tgatctgatt atccgtcgta
      781 ccgatggttc tccaacctat aacttctgtg tggttgtcga tgactgggat atggaaatca
      841 cccacgttat ccgtggcgaa gaccatatca acaacacgcc acgccagatc aacattctta
      901 aagcactgaa agcgccggta ccggtttacg cgcacgtttc tatgatcaac ggcgatgacg
      961 gcaaaaaact gtccaaacgt cacggggcgg tcagcgtaat gcagtatcgt gatgatggtt
     1021 atttgccaga agcactgctg aactatctgg tgcgtctggg ctggtcccac ggcgatcagg
     1081 aaatcttcac tcgtgaagag atgatcaaat acttcaccct gaatgccgtc agcaaatctg
     1141 ccagtgcgtt caacaccgac aagctgctgt ggctgaacca tcactacatt aacgcgctgc
     1201 cgccggagta tgttgctact cacttacagt ggcacattga gcaggaaaat atcgataccc
     1261 gtaacggccc gcagctggct gatctggtga aactgctggg cgaacgctgc aagacgctga
     1321 aagagatggc acagagctgc cgttatttct acgaagattt tgctgagttc gatgccgacg
     1381 ccgcgaaaaa acatctgcgt ccggtagcgc gtcagccgct ggaagtggtt cgtgacaaac
     1441 tggccgcgat tactgactgg accactgaaa acgttcatca cgctattcag gcgacggcgg
     1501 atgagctgga agtgggtatg ggtaaagttg gtatgccgct gcgtgtcgcc gttaccggtg
     1561 cggggcagtc tccggcactg gatgttaccg ttcacgcaat cggtaagacc cgcagtatcg
     1621 agcgtatcaa caaagcgctg gcttttattg ctgaacgcga aaatcagcag taattagcgc
     1681 ataaaagata aacggcagga gagatacccc tgccgttttt tatttattct gattcatcta
     1741 tgtcgagacg agcaaggaaa tgacgaattc cttcgcgtga caaaaattgc gcaacttttt
     1801 cctgctcact gtgagtcatg ttgtctattg cgctgatgat ttgccgataa gcaggagtgc
     1861 gaatccccgg tgcgtattcg gcaaggggtt cttcggcttc cagaagcatc ggcgtgttat
     1921 ggaaggctgg cgtgttctga ataaactcgc aaacttgcgt atcgaccaga ataagtctgg
     1981 cacgaccgcc tttcacgcca ggaaattttt ccgttttcca gcctttttct ctgatccaac
     2041 ggttaacagt ttgtttagcc acaccgaggc attcagccag ttcttcggtg gtcattttat
     2101 tgcgtaatct tttcatatta tttgctatcg cgaatcccta agcgttgtaa taatccgata
     2161 atcccttccc gcagaagcaa ggatgtaaac tgtttttgtt caactggcgt catctctttc
     2221 gccagtgtca ccagcaacac ttcaagcggc gcatcaccag acagggcagg cgcttctccc
     2281 tgaccttctg gacgttcagc attgcgaata tattcacgaa cctgttcatt gacgtgaacc
     2341 agtcgggctt tgccaccctg gacgccaggt tttggtgacg ttgtccagcc ttccttgcgt
     2401 acccatttat taatggtctg gcggctatag ccggtcagtc tggcaagttc atctggcgtc
     2461 atcctctcct tgaacataac aattccctga atgtatgtgg gtctattagt agttcatttt
     2521 ataacaccac tttacaggaa accgtgacat gaataactac tgaatgcgag cggttttcca
     2581 aaattgttca tttgcctgat ttttcagcga ttgaaactac acgttgcaat ttgccgttga
     2641 cacattcggg cggaattcat atgatgccgc ccgtcaactc gacaagcttt acgtgacggg
     2701 gctatagctc agctgggaga gcgcttgcat ggcatgcaag aggtcagcgg ttcgatcccg
     2761 cttagctcca ccaaatttca aaccctcgct gtaaagcggg ggttttttgt ctctgctttt
     2821 tgccgctttt gtaatacagt ctacgtccgg gttagcgccg cctggtgaaa gcatcattgg
     2881 atgaaaaatc ggcaacaggc tggcccctgt ttgcttcgcg atgcgaataa acttattatt
     2941 tgtgtgcctg aaaaccccga tcagtgagag tagtgtactc atgtttgtgg agcataacct
     3001 gataaaaaat atcaagatat tcacactagc gtttacgctc accgtggtac ttattcagct
     3061 atcccgtttt atttcgccac ttgccattat ccattccagt tatatctttc tggcgtggat
     3121 gccactgtgc gtaatgctgt caatcttgtt tatctttggc tggcgcggtg tcgttcccgt
     3181 tttatgcggg atgttttgca ccaatctgtg gaactttcat ctctcttttt tacagaccgc
     3241 ggtcatgctc ggcagccaga cgtttgttgt gttgtgtgcc tgcgcaatat tacgctggca
     3301 gctggggacg cgttggcgtt atggattgac cagccgatat gtctggcaac gtcttttctg
     3361 gcttggtttg gtgacgccga tcggcatcaa atgcagcatg tatcttgtgg gaagcttttt
     3421 tgatttcccg ctaaagatat ccaccttttt cggcgatgcg gatgccattt tcacagtcgt
     3481 tgatttacta agccttttca ccgctgtgct gatttacaac atgcttttct actatctcac
     3541 tcgcatgatt gtaagtcccc actttgcgca gatattgtgg cgcagggata tcgctccgtc
     3601 gttgagcaaa gagaaacgcg catttacctt aagctggctg gcagctctta gcgtgctgct
     3661 acttctgatg tgcacaccgt atgagaatga ctttattgcc ggttacctgg tacctgtttt
     3721 ctttatcatc tttaccctcg gtgtcggtaa gcttcgctat ccgtttttaa atctcacctg
     3781 ggctgtttca acgctttgcc tgctgaatta caaccagaac tttttgcaag gggtactaac
     3841 cgaatattcg ctggcattta ttctcgcggt gctgatttcc tttagcgttt gcctgctcta
     3901 tatggtgcgc atttatcatc gcagtgaatg gcttaatcgc cgctggcatt tgcaggcgct
     3961 gaccgatccg ttaacgctcc tacccaactt tcgtgcgtta gaacaagcgc cggagcaaga
     4021 ggcgggcaag agtttttgct gcctgcgcat tgataatctt gagtttatga gtcgtcatta
     4081 cggcttaatg atgcgcgttc actgtatccg atcaatttac cgtacgctgc tgccgttgat
     4141 gcaggaaaac gaaaagttgt atcaattgcc gggtagtgaa ctgctgttag tgctgagcgg
     4201 gccggaaacg gaagggcgac tccagcatat ggttaacatc ctgaatagtc ggcaaattca
     4261 ttggaacaat accgggctgg atatgggcta tggtgctgcc tgggggcgtt ttgatggaaa
     4321 tcaggaaacc ctgcaaccct tgttggggca gttaagctgg ctggcggagc aatcctgcgc
     4381 acatcaccat gtgctggcgc tggatagcag agaggagatg gtttccgggc agaccactaa
     4441 acaggtgcta ttgctgaata ccattcgtac ggcgttagat cagggtgatt tgctgctcta
     4501 cgcccagcca attcgcaaca aagagggtga aggttatgat gagatcctcg cgcgactgaa
     4561 atatgacggc ggcattatga ccccggataa gtttctgccc cttattgctc agtttaacct
     4621 tagcgcgcgt tttgatttgc aagtgctgga atccctgttg aagtggctgg caacacatcc
     4681 ttgcgacaaa aaaggcccgc gcttttcagt caatttaatg ccgctcacgc tgctgcaaaa
     4741 gaatattgcc gggcggatta ttcgtctgtt taagcgttat cacatctccc cgcaggcggt
     4801 cattcttgag atcaccgagg agcaggcgtt ttctaacgca gaaagcagca tgtacaacat
     4861 cgagcaactg cataagtttg gtttccggat tgcgattgat gactttggca ccggctatgc
     4921 caactacgaa cggttaaagc gtttgcaggc tgatatcatc aaaattgatg gcgtctttgt
     4981 gaaagatatc gtcacgaata cgctggatgc gatgattgtg agatcaatta ccgatctggc
     5041 gaaagcgaag tcattgagtg tggtcgcgga gtttgtcgag acgcaacagc agcaggcgct
     5101 attgcataag ctcggggtgc aatatctgca aggttatttg attggtcgcc cgcagccatt
     5161 agctgattaa caggcgtaaa aaaaaccggg gaattatccc cggctttttt atgtatggtc
     5221 ttacagcacc agtgctgcga ttgacgcaga cagcacactc accagggtag agccgtaaac
     5281 cagcttcaga ccgaagcgag aaaccacgtt accttgctct tcattcaggc ctttaactgc
     5341 acctgcgata atcccgattg aagagaagtt agcgaaggaa accaggaaca cagagatgat
     5401 gccttcagca cgcggagaga gtgtagaggc aattttctgc agatccatca tcgcaacgaa
     5461 ctcgttggaa accagtttgg tcgccatgat actgcccact tgcagtgctt cactggaagg
     5521 aacacccatc acccatgcaa tcggatagaa gatgtagccc aggatgccct ggaaggagat
     5581 gctgtagcca aaccagccag tcacggtggc aaacagtgcg ttcagcgcgg cgatcagggc
     5641 gataaagccg atcagcatcg cggcaacgat aatggccact ttgaaacctg ccagaatgta
     5701 ttcacccagc atttcgaaga agctctgacc ttcgtgcagg ttggacatct gaatgttctc
     5761 ttcgctggca tcaacacggt aagggttgat cagcgacagc acgataaagg tgctgaacat
     5821 gttcagtacc agcgccgcaa cgacatattt cggctccagc atggtcatgt atgcaccaac
     5881 gatggacatc gacacggtgg acatcgccgt tgcagccatg gtgtacatac gattacggga
     5941 gattttgccg aggatatctt tataggcaat aaagttttca gactgaccca gaatcaggga
     6001 gctgacggcg ttaaaggatt ccagtttgcc catgccgttg actttggaga gcaggaaacc
     6061 aattgcgcgg ataatcaccg gcaacacgcg aatgtgctgg agaataccga tcagtgcaga
     6121 gataaagacg attgggcaca gcactttcag gaagaagaat gccaggcctt gatcattcat
     6181 gctaccaaag acgaagttag tcccttcgtt ggcaaatccg agcagttttt cgaacatttc
     6241 ggagaagcct ttcacgaagc ctaaaccaac gtcggagttc aggaagaacc acgccagtaa
     6301 cacttcgata acaagcagtt gaataacata acggatacga atttttttgc ggtcgctgct
     6361 taccagcagt gcgagaatcg caacaacggc aagtgccagt acaaaatgaa ggacgcggtc
     6421 catatttgct ccaaatatga ggcaggttaa atttccgtgc acattctatg taacatggtt
     6481 aaggaaaacg agatctgaca cacactataa tgacgtcctg tgacaagctt caaaaatagt
     6541 gagctgtcat acatttctgc tatgttgtgt atggaagctg aaagttatgt aaatgtgcta
     6601 acattaaaca taaccataac attcaagtca tcaatctttt cgtagtcata atcctggtct
     6661 atcagagaaa tcaccacaac ccatttaaat gaatttgata atcattctcg tttggcatag
     6721 catgaaacat agcaaaggct atgttttaga ggcacaagat gacgaactat cgcgttgaga
     6781 gtagcagcgg acgggcggcg cgcaagatga ggctcgcatt aatgggacct gcgttcattg
     6841 cggcgattgg ttatatcgat cccggtaact ttgcgaccaa tattcaggcg ggtgccagct
     6901 tcggctatca gctactgtgg gttgtcgttt gggccaacct gatggcgatg ctgattcaga
     6961 tcctctctgc caaactgggg attgccaccg gtaaaaatct ggcggagcag attcgtgatc
     7021 actatccgcg tcccgtagtg tggttctatt gggttcaggc agaaattatt gcgatggcaa
     7081 ccgacctggc ggaatttatt ggtgcggcga tcggttttaa actcattctt ggtgtttcgt
     7141 tgttgcaggg cgcggtgctg acggggatcg cgactttcct gattttaatg ctgcaacgtc
     7201 gcgggcaaaa accgctggag aaagtgattg gtgggttact gttgtttgtt gccgcggctt
     7261 acattgtcga gttgattttc tcccagccta acctggcgca gctgggtaaa ggaatggtga
     7321 tcccgagttt acctacttcg gaggcggtct tcctggcagc aggcgtgttg ggggcgacga
     7381 ttatgccgca tgtgatttat ttgcactctt cgctcactca gcatttacat ggcggttcgc
     7441 gtcaacaacg ttattccgcc accaaatggg atgtggctat cgccatgact attgccggtt
     7501 ttgtcaatct ggcgatgatg gctacagctg cggcggcgtt ccacttttct ggtcatactg
     7561 gtgttgccga tcttgatgag gcttatctga cgctgcaacc gttgttaagc catgctgcgg
     7621 caacggtctt tggattaagc ctggttgctg ccggactgtc ttcaacggtg gtggggacac
     7681 tggcggggca ggtggtgatg cagggcttca ttcgctttca tatcccgctg tgggtgcgtc
     7741 gtacagtcac tatgttgcca tcatttattg tcattctgat gggattagat ccgacacgga
     7801 ttctggttat gagtcaggtg ttgttaagtt ttggtatcgc cctggcgctg gttccactgc
     7861 tgattttcac cagtgacagc aagttgatgg gcgatctggt gaacagcaaa cgcgtaaaac
     7921 agacaggctg ggtgattgtg gtgctggtag tggctctgaa tatctggttg ttagtgggta
     7981 cggcgctggg gctatagttc aactggcgtc gtaccaggca tcactggcgg atgcggcgta
     8041 aaacgcctta tccgccctat gcgttaaaga gacggtttgt aggtctgata agacgcgcta
     8101 gcgtcgcatc aggcattgtg ctccattgac ggacgcgttt aatggcgatg cccatgtccg
     8161 cggccttttc cgcgatgatc gtcacgatcg cgccagcctt cacgatagcc acgctcatac
     8221 gctttacgct tatcccagcc acgatggtag ccattatcat gacgccacca gcggttctta
     8281 cgccattcat aattgcgatg ccagtagtca cggtcgcgcc agtgaccacc gtcccagtaa
     8341 ttaccgtaat gatcgcgatc gccaatttgt aatttgattg atggcagtag ggtgatttca
     8401 cctgcgtttg ccgcaagcgg ggtaaatgcc atcagggcgg ccgccagaaa cagtgacctg
     8461 aacattgtta ttctccttca cgatcgaagc cgtcagcggc ctgttaacgc aatgttacgg
     8521 ggaggtaaag ccccgtatca tcgccataac tcttaaatca taaaggagag cattttttgc
     8581 taaacgttat cgtggggtgg ctgttgcttc ggacgattga ccatcatcat cggcttacct
     8641 gctaataaca gccaagccgg aagcatgacg atacagagca gcggtagcaa tgtggtattg
     8701 ggtacaacga ctgccgccat aaaaagactt aaccagccat cgcgtgttac caccagcacg
     8761 atgccgagaa tagcgcagga aacggttatt gccgctggaa cggcgggtac gtgctcatgc
     8821 agcatcaacc ctaatgccac gccgacaaac actgccggga agattcgccc accgcgaaag
     8881 ccactggcgg cagcaacgac cagggcggca agtttaatta ccgccagcaa aaagtaatcg
     8941 ctggtgctga aagcctgatt tgccaccatc tgctgcatct catccagccc tttaaacagc
     9001 gaaactggtc caccaataac ccccagaata ccgagaataa atccgccaat acccagcacg
     9061 agcaccggat ttttcatttg atgcatcatc gcgtgcaacc gtggtaagca ccatacggcg
     9121 accatccctg ctgcgatggc aatcgccgcg acaattgcac cgctgagaat atcggtcatt
     9181 tccatttgtc cgtaatgcgc aatgggcagt gaaaaatggg gatggaaaaa taatccggta
     9241 gtaagtgcac cagctgctgc cgccattaac ggcgcaaaaa gacgatccca tagcggaact
     9301 tcactactac catttaaggt ttgcgaaaat atcaacgccg ccgcaacagg tgtgccaaac
     9361 agcgcgccga tggttccggc agaggctaaa atagtccact ccattcggtt gacgcgcggt
     9421 aacagacgag cgccaatggc aaccgcaagg gcgatattga cggtcatgat cggatgttct
     9481 ggccccaggc tgacgccacc agcaagacca agaattaatg ctacgataag tcctggtagc
     9541 gcagagggcg gaactggtgc gccgatcagc ggttcacagg cggggtctgg tccggcatga
     9601 ccctggctga aacggataac caaccccact gcaatacccg ttagcgttaa tacaccgatg
     9661 atccagagag gtgaatcctg ggctatcccc agagttcccg gcagtcgttg ccagagcaaa
     9721 ttctgtaata ccgaggcgat tttcatcacc acaatcagaa taagactgga cgcaatccca
     9781 attgccacgg cggggagcga taataacaac atggttctgg ctcgcggatg gagcatgttc
     9841 tattccttat gcggggtcag atacttagtt tgcccagctt gcaaaaaggc atcgctgcaa
     9901 ttggtgctga aacgataaag taattgtgtg acccagatcg atatttacag ggagcctgcc
     9961 tttccggcgt tgttgttatg cccccaggta tttacagtgt gagaaagaat tattttgact
    10021 ttagcggagc agttgaagaa tgacaaagta tgcattagtc ggtgatgtgg gcggcaccaa
    10081 cgcacgtctt gctctgtgtg atattgccag tggtgaaatc tcgcaggcta agacctattc
    10141 agggcttgat taccccagcc tcgaagcggt cattcgcgtt tatcttgaag aacataaggt
    10201 cgaggtgaaa gacggctgta ttgccatcgc ttgcccaatt accggtgact gggtggcaat
    10261 gaccaaccat acctgggcgt tctcaattgc cgaaatgaaa aagaatctcg gttttagcca
    10321 tctggaaatt attaacgatt ttaccgctgt atcgatggcg atcccgatgc tgaaaaaaga
    10381 gcatctgatt cagtttggtg gcgcagaacc ggtcgaaggt aagcctattg cggtttacgg
    10441 tgccggaacg gggcttgggg ttgcgcatct ggtccatgtc gataagcgtt gggtaagttt
    10501 gccaggcgaa ggcggtcacg ttgattttgc gccgaatagt gaagaagagg ccattatcct
    10561 cgaaatactg cgtgcagaaa ttggtcatgt ttcggcagag cgcgtgcttt ctggtcctgg
    10621 gctggtgaat ttgtatcgcg cgattgtgaa agccgacaac cgcctgccag aaaatctcaa
    10681 gccaaaagat attactgaac gcgcgctggc tgacagctgc accgattgtc gccgcgcgtt
    10741 gtcgctattt tgtgtgatta tgggtcgttt tggcggcaac cttgcattga cgctgggaac
    10801 tttcggtggg gtttatattg caggtggcat cgtgccacgt ttccttgagt tcttcaaagc
    10861 ctccggtttc cgtgccgcat ttgaggataa agggcgcttt aaagaatatg tccatgatat
    10921 tccggtgtat ctcattgtcc atgacaatcc gggccttctc ggttccggcg cacatttacg
    10981 ccagacctta ggccacattc tgtaactcct tcctgttata tcgggaggta actctcccga
    11041 taatctttta aatcatacag ttaattcaat tttcctttgt gtcccctcac aaggccgacc
    11101 tgcgtcacac ttccgtgcag cgggattaat tctccagtaa atgcattatt tgtctggtaa
    11161 cggcgatttg ttttgcacgt tcataatttc actcgtcaac tatcactgaa cgaggaatta
    11221 acgatgagta agaaactgat tgccttatgt gcctgcccaa tgggcctggc tcacaccttt
    11281 atggccgctc aggcgctgga agaagcggcg gtagaagccg gttatgaagt gaaaattgaa
    11341 acccagggtg cggacggtat ccagaatcgt ctgaccgcgc aggatatcgc cgaagcgacc
    11401 atcatcatcc actccgtggc ggttaccccg gaagataacg aacgtttcga atcacgcgac
    11461 gtttatgaaa tcactttgca ggacgcaatt aaaaacgctg cgggcatcat caaagaaatc
    11521 gaagagatga ttgcctctga acaacagtaa tattcgacag ggataattgt tatggccatt
    11581 aaaaaacgca gtgcaaccgt tgtgcctggc gcatccggtg cggcagcggc agttaagaat
    11641 ccgcaggcct ctaaaagcag cttctggggt gaactcccgc agcatgtgat gtcagggatt
    11701 tcacgcatgg tgccgacctt aattatgggc ggtgtgatcc tcgctttcag ccagctgatt
    11761 gcttatagct ggcttaaaat tcctgctgat atcggcatca tggatgctct taatagcggg
    11821 aaattctccg gtttcgacct ttccttactg aaatttgcct ggctgtcgca atccttcggc
    11881 ggcgtgttgt ttggtttcgc cattccgatg tttgctgcat ttgtggcgaa ctctatcggt
    11941 ggcaaactgg cgttcccggc tggttttatc ggcggcttga tgtctaccca gccgacgcaa
    12001 ctgctgaact tcgatcccag cactatgcaa tgggcgacct cttcgccggt gccgtccacc
    12061 ttcattggtg ccctgattat ttctatcgtt gctggttacc ttgtgaaatg gatgaaccag
    12121 aaaatccagt taccggattt cctgttagcg ttcaaaacca cttttttgct accgattctt
    12181 tccgccattt ttgtcatgct ggcgatgtac tacgtcatca ccccctttgg cggctggatc
    12241 aacggcggta tccgtaccgt gctgactgcc gcaggtgaga agggcgcgct gatgtacgcg
    12301 atggggatcg ccgcggcgac agcaatcgac cttggtggcc cgatcaacaa agcagctggt
    12361 ttcgttgcct tcagctttac cacggaccac gtattaccgg tcaccgcacg ttctatcgct
    12421 atcgttattc cgccgattgg tctgggtctg gcgaccatta tcgaccgccg tttaaccggc
    12481 aaacgcctgt tcaacgctca gctttatccg cagggtaaaa ccgccatgtt cctggccttt
    12541 atggggatca gtgaaggtgc gattccgttt gcactggaaa gccccatcac cgccattccg
    12601 tcctatatgg tcggcgcgat tgtcggctca accgctgcag tctggctggg cgcagtgcaa
    12661 tggttcccgg agtccgctat ctgggcatgg ccgctggtca ctaacctcgg cgtctacatg
    12721 gcggggatcg cgctgggggc agtcataact gcgctgatgg tggtgttcct gcgtctgatg
    12781 atgttccgta aaggcaaatt gttaatcgat agcctgtaag aaggaaaatc cagatgacat
    12841 tactcgcttc gctgcgtgac tggcttaagg cgcaacaact ggatgcggtg cttctctcct
    12901 cacggcagaa caaacagccg catctgggga tctccaccgg atcaggctat gtgctgatta
    12961 gccgtgaaag tgcgcacatt ctggtggact cgcgctatta cgcggatgta gaagcccgca
    13021 cgcaaggcta ccagctgcat ttgcttgacg cgacgaacac gcttaccact atcgtcaatc
    13081 aaatcattgc cgatgagcag ttgcaaacgc tcggttttga aggccagcag gtatgttggg
    13141 aaaccgcgca ccgctggcag tctgaactca atgcgaaact ggttagcgcc acgccggatg
    13201 tgctgcggca aatcaaaacg ccagaggagg tggagaaaat ccgcctcgcc tgtgggattg
    13261 ccgatcgcgg tgctgagcat attcgccgct ttattcaggc ggggatgagc gagcgcgaga
    13321 tagccgctga actggagtgg tttatgcgcc agcagggcgc agaaaaagcc tctttcgata
    13381 ccattgtcgc cagcggctgg cgtggggcgc taccgcacgg caaagccagc gacaagattg
    13441 ttgcagcggg cgagtttgtc actctcgatt tcggtgcgct gtatcagggc tactgctctg
    13501 atatgacgcg taccttgctg gtgaatggcg aaggggtgag cgccgaatct cacccgctgt
    13561 ttgacgtcta tcagattgtt ttgcaggcac agctcgcggc aatctccgcg attcgccccg
    13621 gcgtgcgttg ccagcaggtt gacgacgccg cgcgccgggt gattacagaa gccggttatg
    13681 gcgactattt cggtcataac accggtcatg ctatcggcat tgaagtccat gaagatccgc
    13741 gtttttcacc gcgggacacc acgacgctac agccaggcat gttactgacc gtggagccgg
    13801 ggatttattt gccagggcaa gggggcgtgc gcatcgagga tgttgtgctg gtcaccccgc
    13861 aaggcgcaga agtgctctac gccatgccga aaacagtgtt gctcacggga gaggcataat
    13921 ggatttatcg ctattaaaag cgttgagcga ggcagatgcg atcgcctcct cggaacagga
    13981 agtgcggcag atcctgctgg aagaagcgga tcgcctgcaa aaggaggtgc gatttgatgg
    14041 tctgggatcg gtgctgatcc gcctcaatga atcgacaggt ccgaaggtga tgatctgtgc
    14101 gcatatggat gaagtgggat ttatggtgcg cagcatctcc cgcgaagggg cgattgatgt
    14161 gctgccagtt ggtaacgtgc gcatggctgc ccgccagctg cagccggtgc gcatcaccac
    14221 ccgtgaagag tgcaaaattc ccggtctgct tgatggcgac cggcagggaa atgacgtcag
    14281 caccatgcgc gtggacattg gcgctcgctc gtatgacgaa gtgatgcagg cgggaattcg
    14341 tccaggcgat cgcgtcacct ttgatacaac ttttcaggtt ctaccccacc agcgagtgat
    14401 ggggaaagcc tttgatgacc gcctcggttg ctatctgctg gtgacgttac tgcgtgagct
    14461 gcacgacgcc gaactgcctg cggaagtgtg gctggtggca agttccagcg aagaggtggg
    14521 attacgcggc gggaaaactg ccacccgcgc ggtgtcgccg gatgtcgcca ttgtgcttga
    14581 taccgcctgc tgggcgaaaa actttgatta tggcgcggct aaccatcgcc agattggtaa
    14641 cgggccgatg ctggtattaa gcgacaagtc gctgattgcg ccgccaaaac ttaccgcgtg
    14701 gattgaaacc gtggcggcag aaattggcgt accgttgcag gcggatatgt tcagcaacgg
    14761 cggcacagat ggcggagcgg tgcatttaac tggcaccggc gtacccacgg tggtgatggg
    14821 gccagcgacg cgccacggac attgtgcggc atcgattgcc gattgccgcg acattttgca
    14881 gatgcagcaa cttttatctg cccttattca acgtcttacg cgtgagacgg ttgttcaact
    14941 gacggatttc agatgatctc ctgattaacc cggagcggtt atgttaacga ttcaatttct
    15001 ctgtcctttg cctaacggta ttcatgctcg tccggcgtgg gaacttaaag aacagtgcag
    15061 ccagtggcaa agcgaaatca cttttattaa ccatcgccag aacgcaaagg ccgatgcgaa
    15121 aagttcgctg gcgctgattg gcaccggcac tttatttaat gacagttgca gcctgaacat
    15181 tagcggcagc gatgaagagc aggcgcggcg cgtgctggaa gagtacatcc aggtgcgctt
    15241 tatcgacagc gacagcatcc agccaacaca ggcagaactg acggcgcatc cgctgccgcg
    15301 ttcattaagc cgtctgaatc ctgatttact gtacggcaat gtgctggcaa gcggcgtcgg
    15361 cgtgggtacg ctgaccctgt tacagagcga cagcctcgac agttatcggg ccatcccggc
    15421 cagtgcgcaa gactccaccc ggctggagca cagcctggca acgcttgccg agcaactgaa
    15481 ccagcagctg cgtgagcgtg acggcgaaag caaaactatc ctcagcgccc atttgtcgct
    15541 gattcaggat gatgaatttg caggcaatat ccgtcacctg atggcagaac agcatcaggg
    15601 gctgggggcg gcgatcatca gcaatatgga gcaggtttgt gccaaacttt ctgcttctgc
    15661 cagcgattat ctgcgcgagc gggtcagcga cattcgcgat atcagcgaac agttactgca
    15721 tatcacctgg ccggaactaa aaccgcgcaa taatctggtg cttgaaaaac cgactattct
    15781 ggtggctgaa gatttaaccc caagccagtt tttgagcctc gatttaaaaa atcttgcggg
    15841 catgattctg gagaaaaccg ggcgcacctc gcataccctg attctggccc gcgcctcggc
    15901 gatcccggta ctgagcggcc tgccgctgga tgcgattgcc cgttatgccg ggcaaccggc
    15961 agtgcttgac gcccagtgcg gcgtgctggc gattaacccg aatgacgcgg tgagcggtta
    16021 ttatcaggtc gcgcagacgc tggcggataa acgccaaaaa caacaggcgc aggctgccgc
    16081 gcagctggct tattcccgtg ataacaagcg tattgatatc gcggcgaata ttggcaccgc
    16141 tctggaagcg cctggcgcgt ttgccaacgg cgcggaaggc gtcgggctgt tccgtaccga
    16201 aatgctctat atggatcgcg acagcgcgcc ggacgagcag gagcaatttg aagcctacca
    16261 gcaggtgcta ctggccgcgg gcgacaagcc gattatcttc cgcacaatgg acatcggcgg
    16321 cgataaaagc attccttacc tcaacattcc ccaggaagag aacccgttcc tcggctatcg
    16381 tgcggtacga atttacccgg aatttgctgg cctgttccgc actcaactgc gggctatttt
    16441 gcgcgccgcc agtttcggca acgcccagtt gatgatcccg atggtccaca gcctcgatca
    16501 gatcttatgg gtgaagggcg agatccaaaa agcgatcgtt gagcttaagc gcgatggcct
    16561 gcgtcatgca gagacgatta cgctgggtat catggtggaa gtgccatcgg tgtgctacat
    16621 catcgatcac ttctgcgatg aggtcgattt cttcagtatc ggttctaacg atatgaccca
    16681 gtatctgtat gcggtcgatc gtaataaccc gcgtgtatcg ccgctatata acccgattac
    16741 gccatcgttc ctgcgcatgt tgcagcaaat agttaccact gcgcatcagc ggggcaaatg
    16801 ggtaggaatt tgcggtgaac tgggcggtga aagccgttat ctgccgctac tgcttgggct
    16861 gggcctggat gagctgagta tgagtagccc gcgcattccg gcggtgaaaa gccagcttcg
    16921 tcaactggat agcgaggcgt gtcgggaact ggcacgtcag gcgtgtgaat gtcgcagcgc
    16981 gcaggaaatt gaagcgttac tcaccgcctt tacgccggaa gaagacgttc gcccgctgct
    17041 ggcgctggag aatatcttcg ttgatcaggc cgttagtaat aaagagcagg cgatccagtt
    17101 tctgtgcggc aacctcggcg ttaacgggcg tactgaacat ccgttcgagc tggaagagga
    17161 tgtctggcag cgggaagaga ttgttaccac cggcgttggt tttggcgtag cgatcccgca
    17221 caccaaatct cagtggatcc gtcattccag tatcagcatt gcccggctgg tgaaaccggt
    17281 tgactggcag tcagaaatgg gcgaagtcga actggtgatc atgctgacac tgggcgctaa
    17341 cgaagggatg aatcatgtga aagtcttctc gcagctggcg cgtaaactgg tgaataaaaa
    17401 cttccgccag tcgctgttcg ccgcgcaaga tgcgcaaagc atcctgacgc tgctggaaac
    17461 ggaattaacc ttctgaagtt agccccgaaa gcgggcgctg tactctcccg gcgtcagacc
    17521 aaactgacgc cggaagacgc gacaaaaata atcgctatcc ggaaaaccgc aacgctgcgc
    17581 cacttcatga atcgacagat gatatttctg caaaatcatc ctcgccttcg ccattcgcac
    17641 ccagcgaaca tactcgataa aacgcatcgt cccatgttgg gcaaacagtt ttgacagatg
    17701 attgggcgtg atattaaaaa actgcgccac gctctcgcgg gtgagcggct gggcataatt
    17761 atcctgaacc cagttacaaa tgctgtgata gagaaaatcg ctgcgcggct gcgaattgcc
    17821 cggtggcata ttcaccacgt tgcggcaaag atgcagcaaa cttaacacca gtggctgaat
    17881 gatattctgc tccagcggtg aacggctaag atgggtgagg gcggtaagca tcgcttcacc
    17941 ttcaccgcgt tgcaggctgg gaagctggat ctggcgagca ggatgcaaca acgacgtggt
    18001 gcggctatcg taaaacgata acccaagcca ggtcggagcg aacaccaggc ttaacagcat
    18061 caccggtttg ttgttgaccg gtaaattagc cgcgcgtgcc ggaataaaca gcatttctcc
    18121 ttccaccata cgttgctgct ttgcttccag cagattgccg tattcgccgc gtagcacgat
    18181 atccagacgg ggaaaatcaa tacataaact gcccactggc aatgaggcag gctggctggc
    18241 aaaccagacg cgccccagta gttgcgggtt aagcaccagg ccgctgaaca gatcggcgaa
    18301 aaattgttga tcggcgggca agcctggtgc tttcatgaaa gttcccgatt aaagatgcat
    18361 taactggcgg aattctttaa ctttgctgcg gctgaccggc acttcaaaat ccagatcttt
    18421 cagccgcaga atataggtgt tattaaacca cggttcgatc tcgcggattt tgttcagatt
    18481 gacacaaaat gagcgatggc agcggaaaaa atgcgacggc ggcagcttgc tgcaaaactc
    18541 ggtaatgttc atcggcatta cgtaggattc acgccgcgta tagacaaagg tcattttctc
    18601 gtgcgcttcg gcgtaataga tatcgttaat tggcgtgaca atgattcgct catctttcac
    18661 cagattaatg gtgtcattct cacgcgttac cgtcgcggca ggcgtactgc tggtctgctg
    18721 ttgttgccag gctgcttcca gtttttgcag catcccggta atgcgtgact cctgatacgg
    18781 tttgagaatg tagtcaaacg cttccagttc aaatgcttct accgcatgtt ctttccacgc
    18841 ggtgatgaac acaataaacg gtttatgggc gaactggctg atgttttgcg ccagcaacac
    18901 gccatccagc gacggaatat tgatatccag aaaaatggcg tcgacgcggt tatgctgcaa
    18961 aaacttcaac acgtccagac cgtcgtcaaa ggtgccgaca atctccatct ggctgtgctc
    19021 tttaattagc cagctcagtt cctgttgtgc caggaattcg tcttcaacaa tgatgacttt
    19081 cacaatatca ctccggctca aagcaataac gtagcctgtg aggcgactgg ggtgcgttgg
    19141 ttaggaatgt aaaacgcaat ttccgtcccc ggttccaggc ggcggatatg cagcccctcg
    19201 ccatacaata acttcacgcg atgatggaca ttcagcaggc caattttatt gcccggcatt
    19261 tcgttcgctt cgacccgctc aatcaccttt ggatcgatgc cgtgcccggt atcccgcacc
    19321 gcaatgcgta cccgattacc gcactctgca acgctgatgg tgacaacgcc tttacctttg
    19381 caaggctgaa taccgtggac aatggcgttc tccaccagcg gctggatcag caggctggga
    19441 atgcagcaat tcacctcttc atcaatatca tagataaccg tcagcttgtc gccaaagcgg
    19501 gcctgctcaa tggcaatata gtctttaatt tgatacagct cttttttgat atcgatttgc
    19561 tcatcgtctt ttaattcaat gttatagcgc agataacgcg acagattaaa gatcagctgg
    19621 cgagcggtat ccggattcag acggattgac gatgaaatag cgttcaaagc gttaaacagg
    19681 aaatggggat taattttgct ttgcagggcg cgaagctctg ccttatttgc catttcacgt
    19741 agctgctcgg cgcgtgaaac ctccagttgc gtggagatga tttgcgacag accgaccgcc
    19801 atttcctgta atgatgacgt aatctgatgc gcgtggcagt agtaaatttt cagtgttccg
    19861 gtcacaacgc ctttctccca caatgggatc accagcatgg aatgaatctc tggtgtgcgg
    19921 tgggcttcat cattgttttt aatgatgatt tttccgtaat tcatcgcctg tcgggtagtc
    19981 gggctaatga agtcatcgcc attctgatag ttgtgttcac ccacgccaac ataggccagc
    20041 acatgatcgg tattggtaat cgccaccgca tcggcatgaa tatcatcgcg gataatttca
    20101 caaactttgc gtaatgactc gctattgaca tggcgaaaca gcggcagcgt tttgttggcg
    20161 atatccagcg ccagcttggc ctgccgcgcg gcgctggcct ctttttcgcc ctcaacgctt
    20221 tgcaccagca gcacaataaa gccgatacag acgctaccga ggatcatcgg aatgccgatt
    20281 ttagagacga tatcgatccc caacgcggta gttggtgccc agacaatcac cagaatcatg
    20341 gtcaacgttt cacataacat gccgccgaga ataccgacgc gccagcgctg tgctttgggg
    20401 attttcaggt tgatccagcc cgatatacaa cccgccagaa tgctggtgat aaagcagggg
    20461 atcgccgtca cgccgccgat atcaattaaa taccggtgaa tacccgcaat cacgccggta
    20521 atgatgccta cccacgggcc aaacagaatc ccgcctgaca tcaccgcgat aatacgaacg
    20581 ttcactagcg agccttctac gggaacgccg gaccaggtgc tgaacagggc gaacagcgag
    20641 aaaatggcgg taacagcgag cagctctttt ggggagtgcg ccgacttgtg caacagttcg
    20701 cgaaacaggc ggatacggat gagaaagaac aggcagataa gcattaacgc tgcccgatcg
    20761 aagaccgcca gcagcatgtt gaatatttcg tgcacgggtg actctgaata aggattaaac
    20821 ctctatgata ggtaacctga aggctgatga ccagcaggcc gtttttgagg aaaaaccaca
    20881 attttaaaag gggattgaaa gataaatggt gtattagcaa tgcatctctt gataatgcac
    20941 atctgcttgg taaatttatt gaaattataa tgttaataaa atgagtggta attttcttgt
    21001 tagcgcagat aaatttcctg tttttgaagt ggagttcctc atttaaagcc attgataaaa
    21061 atgttctaaa acgctggaca gacagaaatt aatcaggcta ttttcaaaac agccaccatc
    21121 gtggcagcgt cgctcggacg gtccgggcgc taacgttaat ctgaggaaat tatggctgac
    21181 actcgccctg aacgtcgctt tacgcgcatt gatcgtctcc cgccctacgt ttttaatatt
    21241 accgctgaac tgaaaatggc tgcgcgtcgg cgcggcgaag atattatcga tttcagtatg
    21301 ggtaacccgg acggtgcgac tccgccgcat atcgtcgaaa aattatgtac ggtggcccag
    21361 cgcccggaca cgcatggtta ctccacgtca cgcggcattc cgcggctacg tcgcgccatt
    21421 tcccgctggt atcaggatcg ctacgacgtc gagatcgacc cggaatcaga agccatcgtc
    21481 accattggtt cgaaagaggg actggcgcat ctgatgctgg cgacgctgga tcatggtgac
    21541 actgtactgg tgcctaatcc aagctacccg attcatattt acggcgcggt gattgccggg
    21601 gcgcaggtac gctcagtgcc gctggtggaa ggtgtcgatt tcttcaacga actggaacgc
    21661 gccattcgcg aaagttatcc gaaaccgaag atgatgatcc tcggcttccc gtcgaaccca
    21721 accgcgcaat gcgtggaact ggaattcttt gagaaggttg tggcgctggc aaaacgctac
    21781 gatgtgctgg tggtccatga cctggcctat gccgatatcg tctacgatgg ctggaaagcg
    21841 ccgtcaatca tgcaggtgcc gggcgcacgc gacgtggcgg tcgagttctt taccctgtcg
    21901 aaaagttaca acatggcggg ctggcgtatc ggctttatgg ttggcaacaa aacgctggtc
    21961 agcgcgttgg cacgtattaa aagctatcac gattacggca cctttacgcc gttgcaggtg
    22021 gcagcgattg cggcgctgga gggcgatcag cagtgcgtgc gcgacattgc tgaacagtac
    22081 aaacgccgcc gtgatgtact ggtaaaaggg ctgcatgaag cgggctggat ggtcgaaatg
    22141 ccgaaggctt cgatgtatgt ctgggcgaaa atcccggaac cgtatgctgc catgggctcg
    22201 ctggaatttg ccaagaagct gctgaacgaa gcgaaggtct gtgtctctcc ggggattggc
    22261 tttggcgact acggcgacac gcatgttcgc tttgcactga ttgaaaaccg cgaccgtatt
    22321 cgtcaggcga ttcgtgggat taaagcgatg ttccgtgccg atggtttact acccgccagc
    22381 agcaaacata ttcacgaaaa cgcggaataa acaccgacct caaaaatgca aacaggagcc
    22441 tgatggctcc tgtttttcat tgcacagttt gcttttagat catcagggca aaagtaccgg
    22501 cccaaacgat gaccataaaa gaaatgccca taaagaaata tttcacttta catctctccg
    22561 cgtaattact gttacgcctg aatgacttca ttacacctga tacagtgagt tgacaccggg
    22621 caaaacgacc ttaaaagtcc tgtattttac cgtgggcatc accccagaat tctgagctaa
    22681 actgctccag acggcgctaa tgtacgccta aaactgaaac gagacaagag gcattttctt
    22741 atttactttt agtaacttac aggtgtctca tatcggcgac agtttaattt ctgacggtaa
    22801 taattagaga ttcagcgaag gaaaaaacct taagaaaaaa gccataaaaa ccatgaggtt
    22861 attatggctg atttgaggag ggaaagagtt agagcagttt gttaaatgta tagcgacgat
    22921 tctcccaccg ggcgcgtttt aaagcgacgg tggatccaga ggtactgctc cggtgcgcgc
    22981 atgatctctt tttcgataat cttgttcata taggcagcgg cttgattttc atctgccggg
    23041 tagccttcca tctctggggt gatgtacaaa cgatatccgc tgtaatccgc ttttcttacc
    23101 atcgttacgg ttaacatggc tgcgccagag agacgtgaaa ggacatacgt accattggtt
    23161 gtggcgacat tttccaccgc aaagaacggc gcgaaggagc tgcctttacg accataatcc
    23221 tgatcgggag caaaccatac cgcttcacct ttcttcagtg caccaacaat gccgcgcaga
    23281 ttatttctgc cgatcatcgc tttgttagag cgcatgcgcc cacgggtctg cacccattcc
    23341 atcagctgat tattatgtgg acgataggta gccatcattg gttgacacag tcccatcacg
    23401 cggccgccca gttccagcga cataaaatgg acgccgacaa ccattacgcc gcgattttgc
    23461 atttgtgcgc gtttaaggtt atccagccct tcaacatcaa accatttgcg tacgcgactg
    23521 tcgggccaga accacgccat gccggtttct accagcgcca tgccgagtga acgaaagttt
    23581 tcggcgatca tcttctcgcg ctcttcagca gaatgctgcg ggaaacaaag ttccaggttt
    23641 ttacgggcga tagattcacg ccgtttcagg aatggtcgcg ccattgcgcc aatacgcgtg
    23701 ccgagaaagc agagaacagg ataaggaagc tgtacccaaa gccagagtac accaagccca
    23761 aaccatgtga gccagtagcg aggatgcaga aactcgcggg aaaatttgca ttttggaaac
    23821 atagttacct tctgtagata cgaatcgttg tatcgcagaa gattccatgt cgacagcggt
    23881 acactcaatt ggttgggcca tcatgtacga caatggttcc tgtaaagagt gtaaagacta
    23941 gtcaggacat aaccacgagg agcatgaatg cggtatctgt actttatcac tggctgactg
    24001 ctttcagcta ctgattatta atcgtgcaaa gtaaatattt ttccgtacgc aacagtcttg
    24061 catttaacat gctgttttca ttgatgctta gcaaaaattg ccagaggtta aggattgtct
    24121 tactattaaa ttgactgaag ttacaggttt tttagcgcgg caggaggttg agctatgatt
    24181 tatttatgga tgtttctcgc cctgtgtatt gtctgcgtaa gcggatacat cggtcaggta
    24241 ctgaacgtgg tctcggcggt ctcttctttc ttcggcatgg tgatcctcgc tgcactcatt
    24301 tactacttca ccatgtggtt aacaggcggt aatgaactgg tgacggggat atttatgttt
    24361 cttgccccgg cttgtggctt gatgattcgc tttatggtgg ggtatggcag gcggtagtag
    24421 ttcaggatgg atcatttggg caggtgctca catcatcaac agatatgatt gttcacctgc
    24481 catgtgacag acgctatcgc acaggatgaa taagataatt cgcctttgtc ggaaaagggg
    24541 gcgtgatgtc ttctgtgaga tttaatggtg gcgcatcttc tctcatctta aacaaaatcg
    24601 cctgtgatgg ctgaagtttt gtagaatgag ttgtcgtcat cactgacttt ttttctgtct
    24661 ctttatagct cgtctcactt ccaccaccag aaatggaaaa tgcaaaaaca ttgcatgcca
    24721 taatagagac caataaaaat aagctaaaaa gcattaagtt tactttcata gaaagttatc
    24781 ctgagaa
//
LOCUS       DACAOP010000064        24578 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.064, whole genome shotgun sequence.
ACCESSION   DACAOP010000064 DACAOP010000000
VERSION     DACAOP010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24578
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.064"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..717)
                     /locus_tag="IT892_002900"
     CDS             complement(<1..717)
                     /locus_tag="IT892_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HAP3136095.1"
                     /translation="MPQRILVLGASGYIGQHLVRTLSQQGHQILAAARHVDRLAKLQL
                     ANVSCHKVDLSWPDNLPALLQDIDTVYFLVHSMGEGGDFIAQERQVALNVRDALREVP
                     VKQLIFLSSLQAPPHEQSDHLRARQATADILREANVPVTELRAGIIVGAGSAAFEVMR
                     DMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPASEHRIFEAAGPEVLSYQQQ
                     FEHFMAVSGKRRWLIPIPLPT"
     gene            complement(728..1729)
                     /gene="ltaE"
                     /locus_tag="IT892_002901"
     CDS             complement(728..1729)
                     /gene="ltaE"
                     /locus_tag="IT892_002901"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HAP3136096.1"
                     /translation="MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAA
                     ELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQP
                     IDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRERN
                     LALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAI
                     RWRKMTGGGMRQSGILAAAGIYALKNNVARLQEDHDNAAWMAEQLREAGADVMRQDTN
                     MLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSREQLAEVAAHWRAFLAR"
     gene            complement(1766..3484)
                     /gene="poxB"
                     /locus_tag="IT892_002902"
     CDS             complement(1766..3484)
                     /gene="poxB"
                     /locus_tag="IT892_002902"
                     /EC_number="1.2.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001532507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HAP3136097.1"
                     /translation="MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEW
                     MSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHI
                     PSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
                     GDVALKPAPEGATMHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKE
                     LVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQF
                     PYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKADRKFLDK
                     ALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLK
                     MNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMK
                     LPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVD
                     EALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELA
                     KTNWLR"
     gene            complement(3617..4585)
                     /gene="hcr"
                     /locus_tag="IT892_002903"
     CDS             complement(3617..4585)
                     /gene="hcr"
                     /locus_tag="IT892_002903"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001522746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidoreductase"
                     /protein_id="HAP3136098.1"
                     /translation="MTMPTNQCPWRMQVHHITQETPDVWTISLICHDYYPYRAGQYAL
                     VSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSQWLTRDVKRGDYLWLSDAMG
                     EFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVRVIYNVRTPQDVIFADEW
                     RNYPVTLVAENNVTEGFIAGRLTRELLAGVPDLASRTVMTCGPAPYMDWVEQEVKALG
                     VTRFFKEKFFTPVAEAATSGLKFTKLQPAREFYAPVGTTLLEALESNNVPVVAACRAG
                     VCGCCKTKVVSGEYTVSSTMTLIDAEIAEGYVLACSCHPQGDLVLA"
     gene            complement(4597..6249)
                     /gene="hcp"
                     /locus_tag="IT892_002904"
                     /gene_synonym="priS"
     CDS             complement(4597..6249)
                     /gene="hcp"
                     /locus_tag="IT892_002904"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415394.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HAP3136099.1"
                     /translation="MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQG
                     LSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQC
                     LAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
                     GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSIL
                     DAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLP
                     AHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRS
                     IVGWPGVRHLDGDDFSAVITQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVS
                     REKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLP
                     RLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVK
                     NIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA"
     gene            complement(6393..7292)
                     /gene="lysO"
                     /locus_tag="IT892_002905"
     CDS             complement(6393..7292)
                     /gene="lysO"
                     /locus_tag="IT892_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415395.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lysine exporter LysO"
                     /protein_id="HAP3136100.1"
                     /translation="MFSGLLIILVPLIVGYLIPLRQQAALKVINQLLSWMVYLILFFM
                     GISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRI
                     AMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQ
                     IVLNRRGMIVAVVVVVSSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFG
                     PVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMV
                     PAAIVHGFILSLLVPILIAFFSA"
     gene            complement(7787..8482)
                     /gene="aqpZ"
                     /locus_tag="IT892_002906"
     CDS             complement(7787..8482)
                     /gene="aqpZ"
                     /locus_tag="IT892_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="HAP3136101.1"
                     /translation="MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFG
                     LTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLI
                     ASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG
                     FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGII
                     GGLIYRTLLEKRD"
     gene            8908..10566
                     /locus_tag="IT892_002907"
     CDS             8908..10566
                     /locus_tag="IT892_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HAP3136102.1"
                     /translation="MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTL
                     LLSPESDLYHFERDDFWYPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTP
                     CTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLR
                     DARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEH
                     YFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQA
                     KGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVE
                     HVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWV
                     INELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATV
                     RSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRMAQIPENVPMNLRKIISKAI
                     HRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD"
     gene            complement(10563..11519)
                     /locus_tag="IT892_002908"
     CDS             complement(10563..11519)
                     /locus_tag="IT892_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001322270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF535 domain-containing protein"
                     /protein_id="HAP3136103.1"
                     /translation="MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQ
                     KFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEAL
                     RYHYALLRECMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILF
                     RNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVM
                     EAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHY
                     RLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG"
     gene            11670..12785
                     /gene="macA"
                     /locus_tag="IT892_002909"
     CDS             11670..12785
                     /gene="macA"
                     /locus_tag="IT892_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415399.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide transporter subunit MacA"
                     /protein_id="HAP3136104.1"
                     /translation="MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPG
                     DLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIK
                     EVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTKAVSQQDLDTAATEMAVKQAQI
                     GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA
                     DMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYY
                     ARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETR
                     EREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ"
     gene            12782..14728
                     /gene="macB"
                     /locus_tag="IT892_002910"
     CDS             12782..14728
                     /gene="macB"
                     /locus_tag="IT892_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /protein_id="HAP3136105.1"
                     /translation="MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASG
                     SGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLT
                     AEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALM
                     NGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRD
                     GEIVRNPPAIEKVNVTGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTM
                     LGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYD
                     DLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQ
                     EQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVL
                     RVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMD
                     GVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARAS
                     DVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVT
                     GILFGWLPARNAARLDPVDALARE"
     gene            complement(14801..15025)
                     /gene="cspD"
                     /locus_tag="IT892_002911"
     CDS             complement(14801..15025)
                     /gene="cspD"
                     /locus_tag="IT892_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspD"
                     /protein_id="HAP3136106.1"
                     /translation="MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKA
                     GQSVQFDVHQGPKGNHASVIVPVEVEAAVA"
     gene            15348..15668
                     /gene="clpS"
                     /locus_tag="IT892_002912"
     CDS             15348..15668
                     /gene="clpS"
                     /locus_tag="IT892_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HAP3136107.1"
                     /translation="MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVI
                     DVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCT
                     LEKA"
     gene            15699..17975
                     /gene="clpA"
                     /locus_tag="IT892_002913"
     CDS             15699..17975
                     /gene="clpA"
                     /locus_tag="IT892_002913"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HAP3136108.1"
                     /translation="MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREAL
                     EACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNE
                     VTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
                     EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGV
                     GKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ
                     DTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKD
                     RALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDR
                     HLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLK
                     NLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQL
                     SKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEI
                     EKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDN
                     STDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEV
                     SQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKN
                     ELTYGFQSAQKHKAEAAH"
     gene            complement(18319..18406)
                     /locus_tag="IT892_002914"
     tRNA            complement(18319..18406)
                     /locus_tag="IT892_002914"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18370..18372),aa:Ser,seq:gga)
     gene            complement(18660..18878)
                     /gene="infA"
                     /locus_tag="IT892_002915"
     CDS             complement(18660..18878)
                     /gene="infA"
                     /locus_tag="IT892_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAP3136109.1"
                     /translation="MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNY
                     IRILTGDKVTVELTPYDLSKGRIVFRSR"
     gene            complement(19163..19867)
                     /gene="aat"
                     /locus_tag="IT892_002916"
     CDS             complement(19163..19867)
                     /gene="aat"
                     /locus_tag="IT892_002916"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HAP3136110.1"
                     /translation="MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQR
                     GIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGC
                     ASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFS
                     RMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGR
                     LPNNFWVPRCLFSPQE"
     gene            complement(19909..21630)
                     /gene="cydC"
                     /locus_tag="IT892_002917"
     CDS             complement(19909..21630)
                     /gene="cydC"
                     /locus_tag="IT892_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter ATP-binding
                     protein/permease CydC"
                     /protein_id="HAP3136111.1"
                     /translation="MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLS
                     ASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSK
                     LLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDF
                     TLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGA
                     SDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQP
                     GALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRISDLTDQKPEVTFPDTQTRVA
                     DRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDP
                     QQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALSEIL
                     RRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDAT
                     TESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRY
                     YQFKQGL"
     gene            complement(21631..23397)
                     /gene="cydD"
                     /locus_tag="IT892_002918"
     CDS             complement(21631..23397)
                     /gene="cydD"
                     /locus_tag="IT892_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter
                     permease/ATP-binding protein CydD"
                     /protein_id="HAP3136112.1"
                     /translation="MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWF
                     MARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQV
                     LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFP
                     SNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIF
                     GRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGEL
                     DFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAH
                     PQRGEAELASTDPVTIEAEELFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSL
                     LNALSGFFSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDA
                     SEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLL
                     LDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGR
                     YAELSVAGGPFATLLAHRQEEI"
     gene            complement(23520..24485)
                     /gene="trxB"
                     /locus_tag="IT892_002919"
     CDS             complement(23520..24485)
                     /gene="trxB"
                     /locus_tag="IT892_002919"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAP3136113.1"
                     /translation="MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQL
                     TTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNG
                     EYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
                     EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGV
                     TGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQ
                     TSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK"
BASE COUNT         6121 a         6247 c         6567 g         5643 t
ORIGIN      
        1 ggtggggagg gggatgggga tcaaccagcg gcgcttaccg ctcaccgcca taaaatgttc
       61 aaactgttgc tgataactga gcacctctgg tccggcggct tcgaagatgc ggtgttcgct
      121 ggccggatga tctaacaacg caaccagata gtgcagcaag ttttccagcg caatgggcgt
      181 ggtgcgtgaa cgaacccagc gcggaggcgt taagactggc aggttgtaga ccatatcgcg
      241 catgacttcg aacgccgcgg aacctgcgcc aacgataatt ccggcccgca gttcggtcac
      301 gggtacattc gcttcacgca gaatgtccgc cgtagcctga cgagcacgca gatgatccga
      361 ctgctcatgt ggcggggcct gcaacgaact aagaaagatt aattgcttaa ctggtacttc
      421 acgtagcgca tcgcggacgt tgagagccac ctggcgctcc tgagcgataa aatcgccgcc
      481 ttcgcccatg ctgtgcacca gaaaatagac cgtatcgata tcctgcaaca gggccggtag
      541 gttatccggc cagctgagat cgactttatg gcaactgacg tttgccagtt gcagctttgc
      601 aagcctgtcg acatgacgtg ccgccgccag gatctgatgc ccttgctggc tgagtgtgcg
      661 caccagatgc tgaccaatgt agccactggc accgagaact aaaatgcgtt gcggcacgtc
      721 tctctcctta acgcgccagg aatgcacgcc agtgggcggc gacttccgcc agttgttcgc
      781 gcgagacgtc aagatgcgtc accaggcgga caatcggcga ggcgttaatc agcacgtttc
      841 tcgctttcat gtattcgcct aacgcggcag cattttcttc cccgacgcga acaaacagca
      901 tattggtgtc ctgacgcatc acatccgcgc ctgcttcacg cagctgctcc gccatccagg
      961 cagcgttgtc gtggtcttcc tgcaagcgcg caacgttatt tttcagggca tatatcccgg
     1021 cggcagccag aatgccggac tggcgcatcc cgccacctgt cattttccgc cagcgaatgg
     1081 cacgtttaat gtaatcacga ttaccgacga gtaatgaacc gactggcgtc ccaagacctt
     1141 tcgacaggca aatggtgaac gaatcacaat attgcgtgat ctctttcagt tcgcagccgt
     1201 aagccaccac ggcattaaag atgcgcgcac cgtcaacatg cagcgccaga ttgcgctcgc
     1261 gggtaaattc ccatgcttct ttcaggtatt cccgcggcaa cactttgccg ttgtgggtgt
     1321 tttccagact gagtaatttg gtgcgggcga aatggatatc gtcgggtttg attttcatcg
     1381 ccactttatc cagcggtagc gtgccgtcgg cagccgcgtc tatgggttgc ggttgaatac
     1441 tgcccagcac cgccgcgcca ccggcttcaa acagatagtt atgcgcggcc tgaccgacaa
     1501 tatactcttc gccgcgttcg cagtgactga gcagagcgac caggttggcc tgagtgccgg
     1561 taggcagaaa aatggcggct tctttaccgg aaagctctgc tgcgtagtcc tgcagagcat
     1621 taacggtagg gtcgtctccg taaacgtcgt ccccaaccgg ggcggccatc atcgcttcga
     1681 gcatggcgcg gcttggtcgg gtaacggtat cactgcgtaa atcaatcatg gcatgtcctt
     1741 attatgacgg gaaatgccac cctttttacc ttagccagtt tgttttcgcc agttcgatca
     1801 cttcatcacc gcgtccgctg atgattgcgc gcagcatata caggctgaaa cctttggcct
     1861 gttcgagttt gatctgcggt ggaatggcta actcttcttt ggcgaccacc acatccacca
     1921 acaccggacc gtcgatggag aaggcgcgtt gcagggcttc atcaacttca gacgcttttt
     1981 ctacacggat acccgtaatg ccgcacgctt cggcaatgcg ggcaaagttt gtgtcgtgta
     2041 gttcggtgcc gtcagtcaaa tagccaccag ctttcatctc catcgccaca aagcccagca
     2101 cgctgttgtt aaagacgaca attttcactg gcagtttcat ctgcactact gagaggaaat
     2161 cgcccatcaa catgctaaaa ccgccatcgc cgcacatggc gaccacctga cgttctggct
     2221 ctgtcgcctg cgcacccagc gcctgcggca tggcgttagc catcgaaccg tggttaaacg
     2281 aacctaacag gcgacgcttg ccgttcattt ttagataacg tgccgcccac accgttggcg
     2341 taccaacgtc acaggtgaaa atagcgtcat cggcggcaaa atgactaatt tgctgcgcca
     2401 gatattgcgg gtgaatggct ttctcgctcg gtttagctaa atcgtccagc cctttgcggg
     2461 cgtcgcggta atcttccagc gctttatcca gaaacttgcg atcggctttt tcttccacca
     2521 atggaagcaa tgcacgcaga gtcgacttga tatcgccgac cagtgccata tccaccttgc
     2581 tgtgagcgcc gatgctggct gggttgatat caatctgaat gattttggca tcggtcgggt
     2641 agaaggcgcg gtagggaaat tgcgtgccga gtagcactaa cgtgtcggcg ttcatcatgg
     2701 tatggaaacc tgacgagaag ccgattaacc cggtcattcc aacatcatac ggattatcgt
     2761 attcgacatg ttctttaccg cgcagggcat gaacaatagg cgctttaatt ttcccggcaa
     2821 actcaactaa ctctttatgc gcccccgcgc agccgctgcc acacatcagg gcgatattgc
     2881 tggaataacg cagcagttgc gccagtttgc gtaactcttc ttcttccggc gtcacgactg
     2941 gttgtggcgc atgataccag tgcatggttg ccccttctgg cgcaggtttt aacgccacgt
     3001 cgcctggtaa cacgacaacc gaaacgccac ggttaagcac cgctttgcgc atggcaatcg
     3061 ccagtacttg tgggatctgc tccgggctgg aaaccagctc gcaatagtga ctacattcgc
     3121 ggaatagctc ttgtgggtgg gtttcctgga aatagccgct gccaatttcg ctggagggaa
     3181 tatgagcggc aatcgccagt accggaacgt gattgcggtg gcaatcgaac aggccgttga
     3241 ttaagtgcag gttgccgggg ccgcacgatc cggcgcagac cgccagttct ccgctaagtt
     3301 gtgcttcagc gccagcggca aaggccgcca cttcttcgtg gcgggtggac atccactcga
     3361 tggtgcccat gcgattaaga ctgtcactaa gaccgttcag agagtcgcct gtgactcccc
     3421 agatgcgttt cacccctgcc gattcgagtg ttttggcgat ataagctgca accgtttgtt
     3481 tcatggttct ccatctcctg aatgtgataa cggtaacaag tttagttcat ctgacggagg
     3541 gggaagggat gggagagaaa ggaggcacta acggttaaat agcccgatga aaggaatatc
     3601 atcgggcata aggcgattat gcgagaacca aatccccctg cggatggcag gagcaggcca
     3661 gtacgtaacc ttcagcgatt tcggcgtcga tcagcgtcat tgtgctgctc accgtatatt
     3721 caccggaaac cacttttgtc ttacagcagc cgcaaacacc cgcacggcag gcagcgacaa
     3781 ccggaacgtt attgctttcc agcgcctcca gtagcgtggt gccaaccggg gcgtaaaatt
     3841 ctcgtgccgg ttgcagtttg gtgaatttca gaccgctggt cgccgcttct gctactgggg
     3901 tgaagaattt ctctttaaag aaacgcgtca cgccgagcgc tttcacttcc tgctctaccc
     3961 aatccatata cggagccggg ccgcaggtca tcacggtacg tgaagctaag tcaggtacac
     4021 ctgccagcag ttcgcgagtg agacgaccag cgataaagcc ttcggtaacg ttattttctg
     4081 ccaccagcgt taccggatag ttacgccact catcggcgaa aataacatcc tgcggcgtac
     4141 gcacgttgta gatcacccgc acatcggcct gtggacggtt cttcgcaagc cagcgacgca
     4201 tcgacataat cggcgtgacg ccgcagcctg ccgccagcaa caggaattta tcttctgctt
     4261 tatcgtcgca ggtaaattcc cccatcgcgt ccgaaagcca gagataatca ccgcgtttta
     4321 catcgcgcgt cagccactgg gagccgacac cgtcatcaat ccgccgcacg gtcagggtga
     4381 tatattcact cacgcctggc gtggaggaaa tggtgtaagc acgcagcgtt tccgctgagt
     4441 ttcgcacgct gaccagtgca tattgcccgg cgcgatatgg gtagtaatcg tggcaaatca
     4501 gggaaatcgt ccacacatcc ggcgtttctt gcgtaatgtg atgaacctgc atccgccacg
     4561 ggcattgatt cgttggcatc gtcatcgaca aactccttac gcgctcaaca gttgcttcat
     4621 gtcttcttca acagtggtga tagaacgcag gccgaatttc tcgttcagca ccgccagcag
     4681 gtctggtgtc aggaaaccag gtgcagtcgg gccggtgacg atatttttca cgcccagaga
     4741 aagcagcgtc agcagaatga cgatcgcttt ctgttcaaac caggagagca ccagcgacag
     4801 cggcagatcg ttgacaccgc agcccagttt ctctgccaga gtgacagcca gaataatcgc
     4861 tgagtaagca tcgttacatt gacctgcatc taccagacgc ggcagacctt cgatatcgcc
     4921 aaactcaagt ttgttaaagc gatatttacc acaggcgagg gtcaggatca ggcagtcatc
     4981 cggcacgctg gtggcgaaat cggtgaagta gtggcgctcg ccgcgtgcgc cgtcacagcc
     5041 accaagcagg aagatatgac gcagtttttc acggctcacc agatcaatca gcgtatcagc
     5101 agcgccaagc agcgtctggc gaccaaaacc cacggtgata aggtgcggaa tttcgctgta
     5161 cgggaagcct gccatctgtt gcgcctgggt gataaccgca gagaaatcat caccgtccag
     5221 atgacgcacg ccaggccagc caacaatgct gcgggtccag atacgatcgt cataagcgcc
     5281 tacggttggg tcgatgatgc agttcgaggt catcacgatg gggccaggga aacgagcgaa
     5341 ctccacttgc tgattctgcc agccgctgcc gtagttaccg accagatgct tgaatttacg
     5401 cagctccggg tagccatgcg caggcagcat ttcgccgtgg gtgtagacat taacgcccgt
     5461 gccttcggtc tgttccagca ggttgtagag atctttgaga tcgtgaccgg aaatcagaat
     5521 gcatttaccc gccgtcgctt tgacgttgac ctgggttggc gtcgggtgac cgtatttacc
     5581 ggtttcgcct gcatccagaa tgctcatcac tttgaagttc atctggccga tttccattga
     5641 acactcaaga agcgcgttca tatcggcagg ccaggtcccc agccacgcca tgattttatg
     5701 gtactgggca taaatatcgt tgtcgtattg accgagaaca tgcgcgtgtt ccatataggc
     5761 cgccgcacct ttcaggccat acaggcacag cagacgcagg ccgagaatgt tttcgccaat
     5821 cgccgcttta tctttgttag gggtaaattc tgctgcctga cgttgcagct cgccgagatc
     5881 gtcgctcacc agttgcaggt cagccatcgg gttatcgacg cgcgcgttgg catctacagc
     5941 caggcattgc gctttcagcg cctcgcgcag ggcaatcgct tcacgagcgt aaccgacaat
     6001 acgcggagaa tcgaagttaa cgttggtcag ggttgagaaa aaggcacgtg gcgcgaagct
     6061 gtcaacatcg tggttgatga tgccgtattc acgcgctttt accgcccagg cagaaagccc
     6121 ttgcagcgcc gcgatgagta aatcctgaag gtcagaagtt tccgccgttt taccacacat
     6181 cccctgcgcg tatgagcagc cgtttcctgc cggagtacgg atagtttgtt cacattgcac
     6241 acaaaacatg atcacacctt ttaaagttat atttaatata catgtttaag gttaagacgc
     6301 ttaacgcggg gataaaaggg atttttcatg caactttaag ggagattgat ttagcgcaat
     6361 tttggcggca gggatctacc gccagagagg tattacgcag agaaaaaggc gatgaggatc
     6421 ggcactaaca ggctaagaat aaaaccgtga acaattgccg ccgggaccat atccagcccg
     6481 ccagtacgtt gaagaacggg cagggtgaaa tccattgatg tggcaccgca taagcccagt
     6541 gcagtagagc ggctgcggcg aatcagccca gggatcaaca taatagcaat cagttcacgg
     6601 gccagatcat taaaaaacgc cgcgctcccg attaccggac caaaagattc ggtcaataaa
     6661 ataccggaaa gagaatacca gccgaaaccg gaggccattg ccagcgcggt attgatgggg
     6721 agatcaagaa taaaggcgtt aattaaacca ccaattaatg aactgacaac caccaccacg
     6781 gcgacaatca ttccccggcg attaaggaca atctgcttta aggtcatgcc attattgcgc
     6841 aactgaatac caacgaggaa aagtagcaaa attaacgtgt attcactggc ttcggtcgcg
     6901 tgttgtaaga aagccagtcc acttagacca atggcaaaac caatcactac tacgccgcac
     6961 agttttagcg actccagcgc catcgcaata cgcgacggga gtttttcttg ctgatggtgg
     7021 ttgcgccacg gcaggcctcg ctccagccac atcagggcgg caatattaca cagtaaaata
     7081 acggtaatac tgacggcaga ataatgcaga atcgccaaca ggttactggc gaggttatcg
     7141 agaaacgcca gactgatacc cataaaaaag agaataaggt aaaccatcca gcttaatagc
     7201 tgattaataa cttttaacgc agcttgttgg cgaagcggaa tgaggtaacc cacaatcagg
     7261 ggaaccagaa tgattaacag cccagaaaac atgaaaaccc agtccttgca aagatgaagt
     7321 cgaaatgcgc gatgacacac tactgaaagc ggaaggacga gtaaagttgc aattaaaagg
     7381 aaatgttatg cataaggagc agtagagtat tcgttttcat ttaaagatat tcttgcgctt
     7441 taattacaaa ctgcaccgat gttggtggcg tcaaaatcgc cgaggcgttc cctgaaggcc
     7501 ggggcagccc acatggatgt gggctgaggg cgcgttttac agggatgtta cctcgcgccc
     7561 gacccggtag ccgtaaggga taagtcgagg gcaccgcgca gcggcgattt tgttcgccag
     7621 agcccggggg tgcagggggc ggcggcgatt ggccgccccc tgcgcgctcc ttgcgccagt
     7681 ggcaatatgt tgcttagctc atgaaaggag cgcaacaaga tgatgaatca acatataaca
     7741 acatcttaaa aaaaggcctg acattacgcc aggccttctg cgttaattaa tcacgctttt
     7801 ccagcagggt ccggtaaatc agaccaccga taatgccgcc gacaattggc accacccaga
     7861 agaaccacag ttgttctaat gcccagccgc cctggaagat agcaaccgcg gtgctgcgcg
     7921 ccgggttaac agaagtgtta gtcaccggaa tactaattaa gtgaatcagg gttaaggcca
     7981 gaccaatagc gatcggcgca aaacctgccg gcgcgaattt gtcggttgcg ccgtggatca
     8041 ccaacaggaa acctgcactc aataccagtt caactaccag cgcggaaagc atggaataac
     8101 cgcctggtga atgctcgcca taaccgttag aagcaaaacc gctggctgcc gcgtcaaaac
     8161 ccgttttacc actggcaatt aaatacagca gcgccgctgc aacaataccg ccgacaacct
     8221 gggcaattac gtagccaacg acttcttttg ccggaaaacg tccgccagcc cataaaccaa
     8281 tagtgaccgc cgggttaaaa tgaccaccag aaatatgacc aacagcaaag gccatcgtca
     8341 gaacggtcag accgaacgcc aacgccacgc cggcaaaacc aatgcctaat tccgggaagc
     8401 ctgcggccag tacagcacta ccacagccac caaaaacaag ccagaaagta ccaaaacatt
     8461 cagctgctaa ttttctgaac atatccacct caattaaaaa ttgaccctgt gaaaaatatg
     8521 gtcgttttat agggtcgtcg taaaaaagtg acgacggaaa taatgcgcgg ctattttaaa
     8581 aacgaaggcg agtcattcac cagataaata aatccagtaa atttgattta gggcaacagc
     8641 gggttgcccc atatagtcat ttgtctgatt gacagtgtag tgcacgcaaa agatttaatc
     8701 ctttaggcgt aataaaaaat aatttatcat gctaattatt tgattttgtt gtttttgcag
     8761 acttatcagc aagagggagt ataacgcgat tattcgctca tttttcagac atttgccatg
     8821 cttaaatgtg atgtcatcac gtattagcaa ggcctttccc gttatactgc cagcgtaaag
     8881 gataagtcac atatttctgg aggggatatg attcttgagc gcgttgaaat tgtgggtttt
     8941 cgcggtatca accgtttgtc gttgatgctg gaacaaaaca acgtcctgat tggggagaac
     9001 gcgtggggta aatccagctt gctggacgcc ttaactctgc tgctatcgcc agaatcagat
     9061 ctctaccatt ttgagcgcga cgatttctgg tacccgccgg gagatatcaa cgggcgagaa
     9121 catcatctgc atattatttt gaccttccgc gaatcgctgc caggccgaca tcgggttcgc
     9181 cgttatcggc cgctggaagc gtgctggacg ccatgcaccg atggctatca ccgtattttt
     9241 tatcgtctgg aaggggagag tgcggaagac ggcagcgtga tgacactgcg cagttttctc
     9301 gataaagacg gacatccgat tgatgtcgag gatattaacg atcaggcacg ccatctggtg
     9361 cgtttaatgc cggtgctgcg cttgcgtgat gcccgtttta tgcgccgtat tcgtaacggc
     9421 acggtgccaa atgtccctaa tgtggaagtc accgcgcgcc agctcgattt cctcgcccgt
     9481 gagttatcct cacatccgca aaatctctct gatgggcaga ttcgtcaggg actttccgca
     9541 atggtacagc tgcttgagca ttatttctct gagcaggggg ccggacaggc gcgatatcgt
     9601 ttaatgcggc ggcgagccag caatgagcaa cgaagctggc gctatctgga tatcatcaac
     9661 cggatgattg accgacctgg tgggcgctcg tatcgggtta ttttgctcgg cctatttgct
     9721 actttgttgc aggcaaaagg cacattgcga ctggataaag acgcccgtcc attgttgctg
     9781 atcgaagatc cagaaacccg tttacacccc attatgcttt cagttgcctg gcatctgttg
     9841 aatcttctgc cattgcagcg cattgccacc accaactcgg gtgagttgct ttcgttaacg
     9901 ccggtagagc atgtttgccg actggtacgt gagtcctcgc gcgttgccgc ctggcgtctg
     9961 gggccgagtg gcttgagtac cgaagatagc cgacgcatat cctttcacat tcgttttaac
    10021 cgtccgtcat cgctgtttgc acgctgctgg ttgctggtgg aaggggaaac ggaaacctgg
    10081 gttatcaatg aactggcgcg tcagtgcgga catcattttg atgccgaagg gatcaaggtc
    10141 attgagtttg cccagtccgg gctaaagcca ctggttaaat ttgcccgccg aatggggatt
    10201 gaatggcatg tactggtcga tggcgatgaa gcagggaaga aatatgccgc tacggtacgc
    10261 agcctgttga ataacgatcg ggaagccgaa cgagaacatt taacggcgtt accggcgctg
    10321 gatatggaac attttatgta tcgccaggga ttttccgatg tgttccaccg catggcgcaa
    10381 atcccggaaa atgtaccgat gaatctacgc aaaattatct cgaaagcgat ccatcgctct
    10441 tccaaacccg atcttgccat tgaagtggca atggaggcag gacgtcgtgg tgtggactcc
    10501 gtaccgacgc tgctgaaaaa aatgttctca cgcgtgctgt ggctggcgcg cggtcgcgcg
    10561 gattaaccgc gaaacatcgt ggccatttgt ggctgaatag cgtcgagcat ctcatagcgc
    10621 cgacggtatt cagcccgttt tttactggcg atttcggcaa tctcttttcg tgctatctgt
    10681 gctggaaggc ggtaatggcg ttcagcatca catacgccgc caaccgattc ccagaaagcg
    10741 ttgtaatcag cgtggatctt gccttcttta tcgcgataac gcaggctgcg gtaaatatgc
    10801 gtttcattgc tgacggcaat aatctgctct acctgcaaac gttgggcaaa cagacaggcc
    10861 gcttccatca cgaggcgttt gggaaatagc ccgtggcagg ctttcgtcgc attctggatt
    10921 tcctgatgtg gaatttccca ttttgcgcct tgcagtccgc caataaacat cgttcttttc
    10981 ccctgatatt cacacagggt aaacgtgatc tctgccagag gaataccttc gctgttgcgg
    11041 aacaggattg tgctgtcacc ttctttatcc attgagatca tcatggtcag ctcaagcgtg
    11101 aactgctcgc cgtttttgcc ttccagcttc gccagttgca gcccgggggt attcaaatat
    11161 aagctgaatt cttccgccga catacattcg cggagtaacg cataatggta acgtaacgcc
    11221 tccagcaatt gcttacggct aagattcgcc gcaaggtaag ggcgatgcag acgcacaggc
    11281 agtcgcggct ggcgcgttaa caatacattg agattaggcc agtgggaaag ttcgttcatc
    11341 cactcaacgc ttaaacgcgg cataatcaac gagcgcagca aaaatttctg gcgaaaacta
    11401 cggcgatgcc agaatttacc cggccgacac tgtccacgtg ccagactaag aaaaagtgac
    11461 aggctgctga gagattcaga tggcgtaaag gtccgttcag ttagctgcga catattcatg
    11521 aaatcaatgg ttatacatgg cgtcgatttc accattgcgt atcttaacca aacatcaata
    11581 gtgtgattac taacgtaaat tttagggttt tgttgatatt tcgttgaagt taatgacccg
    11641 gattggcata tggagtattc agaaaattta tgaaaaagcg gaaaaccgtg aagaagcgtt
    11701 acgttattgc gctggtgata gtcatcgccg gactgattac gttatggaga attcttaacg
    11761 cacccgtgcc gacttatcag acgctgattg tgcgccccgg tgatttacag caaagcgtgc
    11821 tggcgaccgg aaagctggac gcgctgcgta aggttgatgt gggcgcgcag gtcagcggtc
    11881 agttgaaaac tctgtcggtg gcgattggcg ataaagtaaa aaaagaccag cttttagggg
    11941 ttattgatcc tgaacaggct gaaaaccaga ttaaggaggt cgaagcaacg ctgatggagc
    12001 tacgtgcgca gcggcagcag gcggaagcgg agctgaaact ggcgcgggtg acgtattccc
    12061 gtcagcaacg tctggcacaa acgaaggctg tttcacagca ggatctcgac accgccgcga
    12121 cggagatggc tgtgaaacag gcgcaaattg gcaccattga cgcgcaaatc aagcgcaatc
    12181 aggcttctct cgatacggct aaaaccaatc tcgattacac tcgcatcgtt gccccgatgg
    12241 ccggggaagt cacgcaaatc accactctgc aaggccagac ggtgattgcc gcacaacaag
    12301 caccgaacat tctgacgctg gcagatatga gcaccatgct ggtaaaagcg caggtttctg
    12361 aagcggatgt aatccacctg aagccggggc aaaaagcctg gtttacggtg cttggcgatc
    12421 cactgacgcg ctacgagggg caaatcaagg atgtactacc gacgccggaa aaggttaacg
    12481 acgctatttt ctattacgcc cgttttgaag tccccaaccc caatggtttg ctgcggctgg
    12541 atatgactgc gcaagtgcat attcagctca ccgatgtgaa aaatgtgctg acgatccctc
    12601 tgtcggcgtt aggcgatccg gttggcgata atcgttataa agtcaaattg ttgcgtaatg
    12661 gtgaaacacg cgagcgtgaa gtgacgattg gcgcacgtaa cgataccgat gttgagattg
    12721 tcaaagggct tgaagcgggc gatgaagtgg tgattggtga ggccaaacca ggagctgcac
    12781 aatgacgcct ttgctcgaat taaaggatat tcgtcgcagc tatcctgccg gtgatgagca
    12841 ggttgaggtg ctgaagggca tcagcctcga tatttatgcg ggtgagatgg tcgcgattgt
    12901 tggcgcttcg ggttccggta aatcgaccct gatgaatatt ctcggctgtc tggataaggc
    12961 caccagcggc acctatcgcg tcgccggtca ggatgttgcc acgctggacg ccgatgcgct
    13021 ggcgcaactg cgccgcgagc atttcggctt tattttccag cgttaccatt tgctttcgca
    13081 tttaaccgcc gagcagaacg ttgaagtacc cgccgtctat gctggtcttg agcggaaaca
    13141 gcgactgctt cgtgcccagg agttgctgca acggctgggg ctggaagacc gtacagagta
    13201 ttatccggca cagctttcgg gtggtcagca acagcgcgtc agcatcgcgc gggcattgat
    13261 gaacggtggt caggtaattc ttgccgatga accaaccggc gcactggaca gccattctgg
    13321 cgaagaggtg atggcgatcc tgcatcagct gcgcgatcgt gggcatacgg tgattatcgt
    13381 cacccacgat ccgcaggtcg ctgctcaggc cgagcgggtg atcgaaattc gcgacggcga
    13441 aattgtgcgc aatcctcccg ccattgaaaa agtgaatgtt actggcggga cggaacctgt
    13501 tgtcaacacg gtgtctggct ggcggcagtt tgtcagcggt tttaacgagg cgctgacgat
    13561 ggcatggcgg gcgctggcag cgaataaaat gcgtacttta ctgaccatgc tggggattat
    13621 tatcggtatt gcgtcggtgg tttccattgt cgtggtgggt gacgccgcca aacaaatggt
    13681 gctggcggat attcgttcta ttggtacgaa tactattgat gtctatcccg ggaaagattt
    13741 tggcgatgac gatccgcaat atcagcaggc gctgaagtac gacgacttaa tcgccatcca
    13801 aaaacaaccg tgggtcgcct cagccacacc tgccgtctcg caaaacctgc gcctgcgtta
    13861 taacaatgtt gatgttgctg ccagtgccaa tggcgtgagc ggcgattatt ttaatgtcta
    13921 tggcatgacc ttcagtgaag gaaacacctt taatcaggag cagctgaacg gtcgtgcgca
    13981 ggtcgtggtt ctcgacagta atactcgccg ccagcttttc ccccataaag cagatgtggt
    14041 tggcgaggtg attctggtcg gcaatatgcc cgccagagtc attggtgtgg cggaagaaaa
    14101 acagtcgatg tttggtagca gtaaagtgct gcgtgtctgg ctaccttaca gcacgatgtc
    14161 cgggcgagtt atgggccagt cgtggcttaa ctccattact gtcagggtga aagaaggatt
    14221 tgacagcgcc gaggcggaac agcaactcac gcgtttactt tcactgcgcc acggaaagaa
    14281 ggatttcttt acctggaaca tggacggcgt cttgaaaact gttgaaaaga ccacacgtac
    14341 tttacaactg tttctgacgc tggtggcggt gatttcgctg gtggtgggcg gtattggtgt
    14401 aatgaatatt atgctggtgt cagtgaccga gcggacgcgg gaaattggca ttcgcatggc
    14461 tgtaggtgcg cgagcaagcg atgttttgca acagttcctg atcgaagccg tactggtttg
    14521 cctggtcggt ggcgcgttgg gaataacact gtcactgtta attgctttca ccttgcagct
    14581 tttcttaccc ggctgggaga ttggtttttc accgttggcg ctgctgctgg cgtttctctg
    14641 ctcgacggtc accgggattt tatttggctg gttacccgca cgaaatgcgg cacgactgga
    14701 tccagtagat gctctggcac gagagtaatt tttgagataa aaatgccagc cgatcgggct
    14761 ggcattttgc ctttaggatg tacacaatga gacagaagag ctatgcgact gccgcttcta
    14821 cttcgacggg cacaataaca ctggcgtgat tgccttttgg cccctggtgg acatcaaact
    14881 gaacggattg tccagctttt agcgttctgt aaccatccat ctgaatggtg gaataatgag
    14941 cgaaaatatc ttcgccgccg ccttcagggc agatgaaacc aaaccctttg gcattgttga
    15001 accacttaac agtacccttt tccatgcttc gacatccttc gcaaatctta tacaagtaag
    15061 atggaataaa ccggggtcag agagggggct gttcaaaacc tcgccaactc tagaaataca
    15121 atttagagaa ttagggcgag ccgtcaagca tttgacaggg gacaaggggc aggtatgaat
    15181 caaaaatttg aagcagttaa cgctattgac aggaatgtga cagatgtcgc tgatgccaac
    15241 gatagatgat agttatctat catgtggagt agattggtca ggcaaataag ctcttgtcag
    15301 cggcagggcg ttctgccgat aaccgtaacc gaagatgata actgacaatg ggtaaaacga
    15361 acgactggct ggactttgat caactggcgg aagaaaaagt tcgcgacgcg ctaaaaccgc
    15421 catctatgta taaagtgata ttagtcaatg atgattacac tccgatggag tttgttattg
    15481 acgtgttaca aaaattcttt tcttatgatg tagaacgtgc aacgcaattg atgctcgctg
    15541 ttcactacca ggggaaggcc atttgcggag tctttaccgc cgaggttgca gaaaccaaag
    15601 tggcgatggt gaacaagtac gcgagggaga atgagcatcc attgctgtgt acgctagaaa
    15661 aagcctgaat gcaggcataa aaattggggg aggtgcctat gctcaatcaa gaactggaac
    15721 tcagtttaaa tatggctttc gccagagcgc gcgagcaccg tcatgagttt atgaccgtcg
    15781 agcacttgtt actggcgctg ctcagtaacc catctgcccg ggaggcgctg gaagcgtgtt
    15841 ctgtggattt ggttgcgctc cgtcaggaac tggaagcctt tattgaacaa accacacccg
    15901 ttctgcctgc cagtgaagag gagcgcgaca cacagccgac gctgagtttt cagcgtgtac
    15961 tgcaacgtgc ggtcttccat gtccagtcct ccggtcgcaa tgaggttacc ggtgcaaacg
    16021 ttctggtcgc tatctttagc gaacaggagt cgcaggcggc atatctgttg cgtaaacatg
    16081 aagtcagccg tctcgatgtg gtgaacttta tctctcatgg cacgcgtaaa gacgagccga
    16141 cacagtcttc tgatcctggc agccagccaa acagcgaaga acaagctggt ggggaggaac
    16201 gtatggagaa tttcacgacg aacctgaatc agcttgcgcg cgtgggcgga atcgacccac
    16261 tgattggtcg tgagaaggag ctggagcgtg ctattcaggt tctctgccgt cgccgtaaaa
    16321 acaacccgct gctggtgggg gaatctggtg tcggtaaaac cgcgattgcg gaaggtcttg
    16381 cctggcgaat tgttcagggc gatgtgccgg aagtgatggc tgactgtacg atttactctc
    16441 tcgatatcgg ttctctgtta gcgggcacaa aatatcgcgg cgactttgaa aaacgtttta
    16501 aagcgttgct caagcagctg gagcaggaca ctaacagcat cctgtttatt gatgagatcc
    16561 acaccattat cggtgcgggt gcagcgtctg gtggtcaggt cgatgcggct aacctaatca
    16621 aaccgttgct ctccagcggt aaaattcgtg taattggttc gacaacctat caggagttca
    16681 gcaacatttt cgagaaagac cgtgctctgg cgcgtcgctt ccagaaaatt gatattactg
    16741 aaccgtcgat cgaagaaact gttcaaatca tcaatggcct gaaaccgaag tatgaagcgc
    16801 accacgacgt gcgttatacc gcaaaagcgg tgcgtgcggc ggtagagctg gcggtgaaat
    16861 acattaacga tcgtcatctg ccggataaag ccattgatgt tatcgacgaa gcgggcgctc
    16921 gcgcacgcct gatgccggta agcaaacgca agaaaaccgt taatgtggcg gatattgagt
    16981 ccgtggtggc ccgtattgca cgcattccag agaagagtgt ttctcagagt gatcgtgata
    17041 ccctgaaaaa cctcggcgat cgcttgaaaa tgctggtctt cggtcaggat aaagccattg
    17101 aggcgctgac tgaagccatt aagatggcgc gtgcaggttt aggtcacgaa cataaaccgg
    17161 ttggttcgtt cctgtttgcc ggccctaccg gggtcgggaa aacagaggtg acggtacagc
    17221 tttcgaaagc tttgggcatt gagcttctgc gctttgatat gtccgagtat atggaacgcc
    17281 ataccgtcag ccgtcttatt ggtgcgcctc cgggatacgt tggttttgat cagggcggtt
    17341 tgctgactga tgcggtcatc aagcatccac atgcggtgct gctgctggac gaaatcgaga
    17401 aagcgcaccc ggacgtgttc aatattctgt tgcaggtgat ggataacggt acgctgaccg
    17461 ataacaacgg acgcaaagca gacttccgta acgtggtgct ggtgatgacc accaacgccg
    17521 gggtacggga aactgagcgc aaatccattg gtcttatcca ccaggataac agcaccgatg
    17581 cgatggaaga gatcaagaag atctttacac cggaattccg taaccgtctc gacaacatta
    17641 tctggtttga tcatctgtca accgacgtga tccatcaggt ggtggataaa ttcatcgtcg
    17701 agttgcaggt tcagctggat cagaaaggtg tttctctgga agtgagccag gaagcgcgta
    17761 actggctggc cgagaaaggt tacgaccggg caatgggcgc tcgtccgatg gcgcgtgtca
    17821 tccaggacaa cctgaaaaaa ccgctcgcca acgaactgct gtttggttcg ctggtggacg
    17881 gcggtcaggt caccgtcgcg ctggataaag agaaaaatga gctgacttac ggattccaga
    17941 gtgcacaaaa gcacaaggcg gaagcagcgc attaatctga ttgttaggta ggttggtcaa
    18001 gtccgtaatc tcgaaagagg ttacggactt tttgtttatg gggtggagga ggttcagacc
    18061 ctttttttaa tgatgatggt aagttgttga taattagtgc tgcgggaagg taaggataaa
    18121 aaagggtgct gcaggagaat gggatggttt tgctttatta acaacgggct aaacgtgtag
    18181 tatttgagtt cactgccgta caggcagctt agaaattcac aggtaacata ctccacccgc
    18241 ccaccatgtt cactgccgta cagacagata aaatgcgaaa aaaaagctcg cactttcgta
    18301 cgagctcttc tttaaatatg gcggtgaggg ggggattcga acccccgata cgttgccgta
    18361 tacacacttt ccaggcgtgc tccttcagcc actcggacac ctcaccaaat tgttttgcta
    18421 ccaaacctca tgggtggcaa cggggcgcta ctatagggag ttggagtaaa acggtcaaga
    18481 agaattttaa tgataattat tgtttgctca tactgtaaac aagttgtgca gtatatctac
    18541 atcgagacaa gttacggact tatacttcca aagtacttca tacatatcac aaaataaaaa
    18601 ggccggttaa accgaccttt tactcgttct ttctcttcgc ccatcaggcg gtaaaacaat
    18661 cagcgactac ggaagacaat gcggcctttg ctcaggtcgt acggggtcag ttcaacagtc
    18721 actttgtcgc ccgtcaggat gcggatgtag tttttgcgca ttttaccgga gatgtgtgca
    18781 gtaaccacgt gaccgttttc taactctacg cggaacatgg tattaggcaa cgtttcaaga
    18841 acggtacctt gcatttcaat attgtcttct ttggccatct aatcctctgg ggtatcacta
    18901 ccgtaatttg aaccggcaag ataatgccga agttctgtaa ataagtaaag atttgcgcgc
    18961 taaatcgcaa caaacaggtt cggcacatta ctccgaaaac acacggctaa gccgcaccaa
    19021 aagcgcaacg tataagggag cggtgagata aacgatgggc gttacctgac gcgaaaaatt
    19081 ccttatcggc agcggggtaa tgagcgtaac caactctgcg accgcaatta taacactctg
    19141 gggagaaatg tgccgaaaac attcattctt gtggtgaaaa caagcatcgt ggtacccaga
    19201 aattattcgg caatcgtccg aggcgcattt gattgagata attaaggtaa tcccggcggg
    19261 gaatttcgca ggcaccaagc gatgctgtgt gatcgttaag gacctggcag tcgataagct
    19321 taccgccatg accgataaat tcctcacaga ataccagaag cgccgtttta gacgcatttt
    19381 ccatccggct gaacatggac tcgccacaaa atagcgttcc ctgggccacg ccgtacatac
    19441 cgccgacaag ctcatcttca cgccagactt caatggagtg ggcatggccg agttcgtgaa
    19501 ggcgatggta ggcttcgacc acgccacgcg tgatccaggt tccttcttcg cgatcgctgg
    19561 cacagccttc aatgacctga ccaaaagcgt aattcatcgt gacacgatag ggcgagcgtt
    19621 tatgaaatcg cttcatacta cggctgatat gcagtgattc tggccatagc accgcgcggg
    19681 gatcgggcga ccaccagagg atggggtcgc ctggagaaaa ccacggaaaa ataccacgct
    19741 ggtaagccat taacaggcgc gcagggctaa gatcgccccc aagtgccagc aggccgttag
    19801 gctcacgtaa tgcgccttcc ggggaaggga aggctattga atggcgagaa agctgaacca
    19861 ggcgcatgac cgcaaaactc cacgcaagtc ggatcgttca ataatagctt acaaaccctg
    19921 cttgaactgg taataacgcc cctgtctggc aagcagttct gcgtgagtac cttgctcaat
    19981 aatttgcccg ttgtccatca ctattatttg ttggaaacga gagagtccgc gaagtcgatg
    20041 ggtgaccatt aacaccgttt tctcacgcat catttctgca agcaattcaa ggatctggct
    20101 ttcggttgtg gcatctaagc cttcggtagg ttcatccagc aacaccagtg gcgcatcatg
    20161 taacagcgca cgggcgatag ccagacggcg cagttcacca ccggagagct ggcgtccgcc
    20221 ttcacctaac caactgttga gacctgcatc ctcgagcagc ttttccaggc caacgcgacg
    20281 caagatctcc gacagagcct catcactact gccaggcgag gcgagtaaaa gattatcacg
    20341 cagcgtggcg ctaaacagat gcactcgctg aggaacaacg ctgatggtct gtcgtagagc
    20401 cgcttcattc aggctggcta tggggctatc gttaagcaaa atctcgccct gttgcgggtc
    20461 ccatgcgcgg gtcagcagtt gtaacagtgt tgatttgccg catccggttc gcccgagaat
    20521 cgctatatgt tccccggcgt ttacctgaag agaaatccct ttaagtgcct gttgagattg
    20581 ctccggataa gtgaactgaa catcccgtaa cgtcagcgaa acgcgatcgg caacacgagt
    20641 ttgggtatca ggaaaggtga cctccggttt ttgatccgtt aagtcagaga tacgtacggc
    20701 agaggcaatg acttgcccca gatgctgaaa tgcacccgtt actggtgcta gtgcttcaaa
    20761 cgcggctaac gcgcagaaga caaacagggc aattaacgcg ccgggttgag cattgccgcc
    20821 aacgccgcca gacgccatcc acagcatcag gatcaccgct aacgcgccaa tgagcagcat
    20881 tatcgcttgc gacaatgcgg tcagttcaga ttgacggcgt tgcgcttcca gccattgaat
    20941 ttctgtattc tctagttgcg tgcgataacg atcgctggca ccaaaaatgg tcagctcagc
    21001 ttgcccttgc agccaggccg tcagttgttg gcgatactgt ccgcgaagat gagtcagatt
    21061 ttgcccggtg ctttttcccg cacgataaaa cagcggtggc atcaggaaaa gcgtcagtaa
    21121 cataatgccg cccagcgtaa aggcgagggt gaaatcaagg aaacttaacc cgattgtcac
    21181 caccataatc accacaaaag cgcccaccag cggcgagata acgcgcaggt aaagatgatc
    21241 gagcgtatca acatccgcca ccacgcgatt gagcaattcg ccctgacgat agcgcgccag
    21301 tccggcaggg gagaggggca gcaatttgct gaaggtgtaa atgcgcagat gctgcaacac
    21361 gcggaaagtc gcgtcgtgac ttaccagacg ttcaaaatag cgcccggcag tacgggtgat
    21421 tgctgcgcca cgcacgcccg cagcgggtag catatagttg aagctgtaca gtccggcaac
    21481 ccccgcaacc gctgaggccg agaggaacca gccggaaagt gtcaacagac cgatactggc
    21541 gagcagcgtc acaattgcca gcacaatacc aagacttaac atccatttat gacgtttata
    21601 cagtgccaga tagggtagca aagcgcgcat ttaaatctcc tcctgacgat gggccagtaa
    21661 tgtggcgaat gggccaccag ccacacttaa ttccgcgtaa cgtccttgct caataatccg
    21721 gccatcctgc ataacccaaa tgacatccca gtcagcaaga tcttctaact ggtgggtgac
    21781 cattaacgtt gtctggcgca gagaggcggc attcagcgcc tccattacgc gctgttcact
    21841 gtgagcatca aggctggcag cgggttcatc caacagtaat agcgaacagg gatttagtaa
    21901 cgcacgggcc accgccacgc gctgcgcctg ccccacggaa aggcgggcag cctggtcgcc
    21961 aacaggcgta tcaacgcctt gtgggaggag cggtagaaac tcgctgaccc aggcgttatc
    22021 cagcgctgct tgtaattctt gttcgctggc atcaggtcgc gccagtagta cgttatcccg
    22081 caatgttgct gccggtaatt gtgggttttg cccaacccag gagagatgtt tacgccatga
    22141 ttctggtgat aaatcgcgta attctatccc gttgattcgt agcgatccct gatatgagaa
    22201 aaaaccagaa agcgcgttca gcagtgagct tttacctgaa ccgctgcgac caaccaacac
    22261 cgcacgttgg cctgctggca aagtaaagtt cagcggtccg gccagcgttt taccttccgg
    22321 cgacgtgata aacagctcct cggcctcaat ggtcaccgga tcggtcgatg ctaattccgc
    22381 ctcaccacgt tgcggatggg cgagcggggt ttccataaac gttttcagac tgtcagctgc
    22441 gccaacagcc tgggctttag catgataaaa cgtaccgaga tcgcgtaatg gctggaaaaa
    22501 ctctggcgca aggatcaggg ccagaaaacc cgcagccagc gtcacaccgg tatcgtagtg
    22561 accaaaatcc agctcgccga gataggaaaa accaaagtag accgccacca gagcaattga
    22621 cagcgaggta aaaaattcga gaatgccgga ggataaaaac gccagccgta gcacttccat
    22681 tgtccgttgg cggaaatctt ccgaagcaga acgaatactt tcaatttcag cttcaccacg
    22741 accaaaaata cgcaatgttt ccatgccgcg caggcgatcg aggaaatgcc cacttaagcg
    22801 agcaagagcg agaaagttac gtcggttagc atcggcagcc cccattccaa ccagcgccat
    22861 aaacaacgga attaacggtg cagtgcccag cagaatgagc gccgcagccc agttagaggg
    22921 gaagattgcc accacaatca gcaacggcac cgacactgcc agcgccattt gcggcagata
    22981 gcgtgcatag taatcatgca tatcgtcaat ttgctcgagt accagcgtcg cccagctccc
    23041 cgcaggttta ccctgaatcc acgctggccc tgcttgttgc agacggtcga gaacctgacg
    23101 gcggatggca aagcggatat gctgcccggc gtgataaccc acccgttcgc gtaaccagac
    23161 cacccatgcg cgcagtacaa aggtcagaac cagtaacgta aagggaagca gcagggcttc
    23221 acggggaata ttctccataa tcatatgttg cagaattcgc gccatgaacc aggcctgggc
    23281 aatgatcaat atgccgctca caaagcccag cagacgagaa atattcagcc aacgttggga
    23341 gatgacgctt tgctgtttta accagcgggt taactctttt tgacgagatt tattcattgc
    23401 acgcttagca ggtgagttat cagaattatt tgcagagcaa tgttacaacg gggaaaaaat
    23461 aaaggcgacc catagtcgca tggtgtcgcc ttctttactt ttgttactga tttgtaaaat
    23521 tattttgcgt cagctaaacc atcgaggtag cgttccgcat caagtgctgc catgcagcct
    23581 gtaccggccg aagtaatggc ctggcgataa atgtgatcca tcacgtcgcc tgcggcaaag
    23641 acgccaggaa tgctggtctg ggtggcatta ccatgaatac ccgactgtac tttgatgtag
    23701 ccgttttcca gttccagctg cccttcgaaa atcgcagtat tcgggctgtg accgatagca
    23761 acaaacagac cggcaacgtc gagtgactcg atgttatcgc tgttttgcgt atcgcgcaga
    23821 cgaacgccag tgacacccat ttgatcgccg gtcacttctt ccagcgtacg gttggtgtgc
    23881 agaatgatgt tgccgttctc cactttatcc atcaggcgct taatgaggat tttttccgcg
    23941 cggaaaccgt cacggcggtg aatcagatgc acttccgaag cgatgttaga cagatacagc
    24001 gcctcttcaa ccgcggtatt gccgccgccg atgaccgcaa ctttctggtt gcgatagaag
    24061 aaaccgtcgc aggttgcaca agcagaaacc ccacggcctt taaaggcttc ttcagagggc
    24121 aggccgagat agcgtgcaga agctccggtg gcaataatca gcgcgtcgca agtgtattcg
    24181 ccgttatcgc cattcagacg gaacggacgg ttttgcagat ccaccttgtt gatatgatca
    24241 aaaatgatct cagtttcaaa cttggtggca tgttcgtgca tgcgctccat taataacgga
    24301 ccggtcagat cgtttggatc gccaggccag ttttccactt ccgtggtggt ggtcagttgg
    24361 ccgccttttt ccatgccggt aatcagcaca ggttgcaggt tggcgcgcgc cgcgtagaca
    24421 gcagcggtgt atcccgccgg gcctgaaccc aggataagca gtttactgtg tttggtcgtg
    24481 cccatgagat ccccatagtt gttggcagac aatgggcagg attgtaggga atttacagac
    24541 gtaaaaaaag agtatgacga ttttgttaac aatttgtg
//
LOCUS       DACAOP010000065        24442 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.065, whole genome shotgun sequence.
ACCESSION   DACAOP010000065 DACAOP010000000
VERSION     DACAOP010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24442
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.065"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            56..751
                     /gene="araD"
                     /locus_tag="IT892_002920"
     CDS             56..751
                     /gene="araD"
                     /locus_tag="IT892_002920"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP3136114.1"
                     /translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPS
                     GVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     gene            826..3177
                     /gene="polB"
                     /locus_tag="IT892_002921"
     CDS             826..3177
                     /gene="polB"
                     /locus_tag="IT892_002921"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="HAP3136115.1"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAF
                     IPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVASRPQLLEKLNTWFANYDPD
                     VIIGWNVVQFDLRMLQKHAERYRLPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
                     RALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     gene            3342..6248
                     /gene="rapA"
                     /locus_tag="IT892_002922"
     CDS             3342..6248
                     /gene="rapA"
                     /locus_tag="IT892_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-associated protein RapA"
                     /protein_id="HAP3136116.1"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     gene            6260..6919
                     /gene="rluA"
                     /locus_tag="IT892_002923"
     CDS             6260..6919
                     /gene="rluA"
                     /locus_tag="IT892_002923"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /protein_id="HAP3136117.1"
                     /translation="MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
     gene            7132..7310
                     /locus_tag="IT892_002924"
                     /pseudo
     CDS             7132..7310
                     /locus_tag="IT892_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244358.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(7327..7485)
                     /locus_tag="IT892_002925"
     CDS             complement(7327..7485)
                     /locus_tag="IT892_002925"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136118.1"
                     /translation="MNGATSLYDEVIIINKIPPKKIDTKGVATEEVATKKVLLNKLLT
                     TQLLNEPE"
     gene            complement(7482..8148)
                     /locus_tag="IT892_002926"
                     /pseudo
     CDS             complement(7482..8148)
                     /locus_tag="IT892_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518734.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8443..9258)
                     /gene="djlA"
                     /locus_tag="IT892_002927"
     CDS             complement(8443..9258)
                     /gene="djlA"
                     /locus_tag="IT892_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlA"
                     /protein_id="HAP3136119.1"
                     /translation="MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQTGGGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     gene            9513..11867
                     /gene="lptD"
                     /locus_tag="IT892_002928"
     CDS             9513..11867
                     /gene="lptD"
                     /locus_tag="IT892_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HAP3136120.1"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQIGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     gene            11920..13206
                     /gene="surA"
                     /locus_tag="IT892_002929"
     CDS             11920..13206
                     /gene="surA"
                     /locus_tag="IT892_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase SurA"
                     /protein_id="HAP3136121.1"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     gene            13206..14195
                     /gene="pdxA"
                     /locus_tag="IT892_002930"
     CDS             13206..14195
                     /gene="pdxA"
                     /locus_tag="IT892_002930"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HAP3136122.1"
                     /translation="MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLT
                     NRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRAPVTAGQLAVENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLNELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ"
     gene            14192..15013
                     /gene="rsmA"
                     /locus_tag="IT892_002931"
     CDS             14192..15013
                     /gene="rsmA"
                     /locus_tag="IT892_002931"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAP3136123.1"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAE
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
     gene            15016..15393
                     /gene="apaG"
                     /locus_tag="IT892_002932"
     CDS             15016..15393
                     /gene="apaG"
                     /locus_tag="IT892_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HAP3136124.1"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     gene            15400..16242
                     /gene="apaH"
                     /locus_tag="IT892_002933"
     CDS             15400..16242
                     /gene="apaH"
                     /locus_tag="IT892_002933"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase
                     (symmetrical)"
                     /protein_id="HAP3136125.1"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLGE
                     AAAS"
     gene            complement(16320..16799)
                     /gene="folA"
                     /locus_tag="IT892_002934"
     CDS             complement(16320..16799)
                     /gene="folA"
                     /locus_tag="IT892_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 3 dihydrofolate reductase"
                     /protein_id="HAP3136126.1"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
                     HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     gene            complement(16991..18853)
                     /gene="kefC"
                     /locus_tag="IT892_002935"
     CDS             complement(16991..18853)
                     /gene="kefC"
                     /locus_tag="IT892_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="HAP3136127.1"
                     /translation="MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGCGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAI
                     PLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     gene            complement(18846..19376)
                     /gene="kefF"
                     /locus_tag="IT892_002936"
     CDS             complement(18846..19376)
                     /gene="kefF"
                     /locus_tag="IT892_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF"
                     /protein_id="HAP3136128.1"
                     /translation="MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     gene            complement(19484..20815)
                     /locus_tag="IT892_002937"
     CDS             complement(19484..20815)
                     /locus_tag="IT892_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136129.1"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
     gene            complement(20872..21159)
                     /gene="fixX"
                     /locus_tag="IT892_002938"
     CDS             complement(20872..21159)
                     /gene="fixX"
                     /locus_tag="IT892_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="HAP3136130.1"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
     gene            complement(21156..22442)
                     /locus_tag="IT892_002939"
     CDS             complement(21156..22442)
                     /locus_tag="IT892_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP3136131.1"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     gene            complement(22493..23434)
                     /locus_tag="IT892_002940"
     CDS             complement(22493..23434)
                     /locus_tag="IT892_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HAP3136132.1"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQA
                     IQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR"
     gene            complement(23449..24219)
                     /locus_tag="IT892_002941"
     CDS             complement(23449..24219)
                     /locus_tag="IT892_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixA"
                     /protein_id="HAP3136133.1"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     ALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
BASE COUNT         5920 a         6714 c         6256 g         5552 t
ORIGIN      
        1 cgctgcgatt ttgtaggccg gataagcaaa gcgcatccgg cacgaaggag tcaacatgtt
       61 agaagatctc aaacgccagg tattagaagc caacctggcg ctgccaaaac acaacctggt
      121 cacgctcaca tggggcaacg tcagcgccgt tgatcgcgag cgcggcgtct ttgtgatcaa
      181 accttccggc gtcgattaca gcgtcatgac cgctgacgat atggtcgtgg ttagcatcga
      241 aaccggtgaa gtggttgaag gtacgaaaaa gccctcctcc gacacgccaa ctcaccggct
      301 gctctatcag gcattcccct ccattggcgg cattgtgcat acgcactcgc gccacgccac
      361 catctgggcg caggcgggtc agtcgattcc agcaaccggc accacccacg ccgactattt
      421 ctacggcacc attccctgca cccgcaaaat gaccgacgca gaaatcaacg gcgaatatga
      481 gtgggaaacc ggtaacgtca tcgtagaaac ctttgaaaaa cagggtatcg atgcagcgca
      541 aatgcccggc gttctggtcc attcccacgg cccgtttgca tggggcaaaa atgccgaaga
      601 tgcggtgcat aacgccatcg tgctggaaga ggtcgcttat atggggatat tctgccgtca
      661 gttagcgccg cagttaccgg atatgcagca aacgctgctg gataaacact atctgcgtaa
      721 gcatggcgcg aaggcatatt acgggcagta atgactgtat aaaaccacag ccaatcaaac
      781 gaaaccaggc tatactcaag cctggttttt tgatggattt tcagcgtggc gcaggcaggt
      841 tttatcttaa cccgacactg gcgggacacc ccgcaaggga cagaagtctc cttctggctg
      901 gcgacggaca acgggccgtt gcaggttacg cttgcaccgc aagagtccgt ggcgtttatt
      961 cccgccgatc aggttccccg cgctcagcat attttgcagg gtgaacaagg ctttcgcctg
     1021 acaccgctgg cgttaaagga ttttcaccgc cagccggtgt atggccttta ctgtcgcgcc
     1081 catcgccaat tgatgaatta cgaaaagcgc ctgcgtgaag gtggcgttac cgtctacgag
     1141 gccgatgtgc gtccgccaga acgctatctg atggagcggt ttatcacctc accggtgtgg
     1201 gtcgagggtg atatgcacaa tggcactatc gttaatgccc gtctgaaacc gcatcccgac
     1261 tatcgtccgc cgctcaagtg ggtttctata gatattgaaa ccacccgcca cggtgagctg
     1321 tactgcatcg gcctggaagg ctgcgggcag cgcatcgttt atatgctggg gccggagaat
     1381 ggcgacgcct cctcgcttga tttcgaactg gaatacgtcg ccagccgccc gcagttgctg
     1441 gaaaaactca acacctggtt tgccaactac gatcctgatg tgatcatcgg ttggaacgtg
     1501 gtgcagttcg atctgcgaat gctgcaaaaa catgccgagc gttaccgtct tccgctgcgt
     1561 cttgggcgcg ataatagcga gctggagtgg cgcgagcacg gctttaaaaa cggcgtcttt
     1621 tttgcccagg ctaaaggtcg gctaattatc gacggtatcg aggcgctgaa atccgcgttc
     1681 tggaatttct cttcattctc gctggaaact gtcgctcagg agctattagg cgaaggaaaa
     1741 tctatcgata acccgtggga tcgaatggac gaaattgacc gccgtttcgc cgaagataaa
     1801 cctgcgctgg caacttataa cctgaaagat tgcgagctgg tgacgcagat cttccacaaa
     1861 actgaaatca tgccattttt actcgaacgg gcaacggtga acggcctgcc ggtggaccga
     1921 cacggcggtt cggtggcggc atttggtcat ctctattttc cgcgaatgca tcgcgctggt
     1981 tatgtcgcgc ctaatctcgg cgaagtgccg ccgcacgcca gccctggcgg ctacgtgatg
     2041 gattcacggc cagggcttta tgattcagtg ctggtgctgg actataaaag cctgtacccg
     2101 tcgatcatcc gcacctttct gattgatccc gtcgggctgg tggaaggcat ggcgcagcct
     2161 gatccagagc acagtaccga aggttttctc gatgcctggt tctcgcgaga aaaacattgc
     2221 ctgccggaga ttgtgactaa catctggcac gggcgcgatg aagccaaacg ccagggtaac
     2281 aaaccgctgt cgcaggcgct gaaaatcatc atgaatgcct tttatggcgt gctcggcacc
     2341 accgcctgcc gcttcttcga tccgcggctg gcatcgtcga tcaccatgcg tggtcatcag
     2401 atcatgcggc aaaccaaagc gttgattgaa gcacagggct acgacgttat ctacggcgat
     2461 accgactcaa cgtttgtctg gctgaaaggc gcacattcgg aagaagaagc ggcgaaaatc
     2521 ggtcgtgcac tggtgcagca cgttaacgcc tggtgggcgg aaacgctgca aaaacaacgg
     2581 ctgaccagcg cattagaact ggagtatgaa acccatttct gccgttttct gatgccaacc
     2641 attcgcggag ccgataccgg cagtaaaaag cgttatgccg gactgattca ggagggcgac
     2701 aagcagcgga tggtgtttaa agggctggaa accgtgcgca ccgactggac gccgctggcc
     2761 cagcagtttc agcaggagct atacctgcgc atcttccgca acgagccata tcaggaatat
     2821 gtacgcgaaa ccatcgacaa actgatggcg ggtgaactgg atgcgcgact ggtttaccgt
     2881 aaacgccttc gccgtccgct gagcgagtat cagcgtaatg tgccgcctca tgtacgcgcc
     2941 gctcgccttg ccgatgaaga aaaccaaaag cgtggtcgcc ccttgcaata tcagaatcgc
     3001 ggcaccatta agtacgtatg gaccaccaac ggcccggagc cgctggacta ccaacgttca
     3061 ccactggatt acgaacacta tctgacccgc cagctacaac ccgtggcgga gggaatactc
     3121 ccttttattg aggataattt tgctacactt atgaccgggc aacttgggct attttgagca
     3181 aaaaaaagag ttcgccagat accattttga tgcgtgacga atgctttgcc atccagtacc
     3241 atagcgccct ttccattcct ggacctgaat aacaccacta cctcataagc acggtagcgg
     3301 gtggttattg cctgcaatta aagatataga gccgaacaca tatgcctttt acacttggtc
     3361 aacgctggat cagcgataca gaaagcgaat tgggacttgg aaccgttgtc gcggtggatg
     3421 cgcgaactgt cactttactt ttcccatcta ctggtgaaaa ccgtctgtac gcacgcagtg
     3481 attcccccgt gacccgcgtg atgttcaacc ctggtgatac cattaccagc catgacggct
     3541 ggcagatgca agtcgaagaa gtaaaagaag aaaatggctt gctgacctat atcggtactc
     3601 gcctggatac tgaagagtcc ggcgtagccc tgcgtgaagt tttccttgat agcaaactgg
     3661 tgttcagcaa accgcaggac cgtctgtttg ccgggcagat tgaccgtatg gaccgctttg
     3721 cgctgcgtta tcgcgcgcgt aaatattcca gcgaacagtt ccgtatgccg tacagcggcc
     3781 tgcgcggtca gcgtaccagc ctgatcccgc atcagctcaa catcgctcat gatgttggtc
     3841 gccgccacgc gccgcgcgtc ctgctggctg acgaagtggg tttagggaaa accattgaag
     3901 ccgggatgat cctgcatcag caactgctct ctggcgctgc tgaacgtgtg ctaattatcg
     3961 tcccggaaac cttacagcat cagtggctgg tagaaatgct gcgccgtttc aacctgcgct
     4021 ttgcgctatt tgatgatgag cgttatgccg aagctcagca cgatgcttac aacccgtttg
     4081 acaccgaaca gctggtgatt tgctcgctgg attttgcccg tcgtagcaaa cagcgcctgg
     4141 aacatctctg tgaagccgaa tgggacctgc tggtggtcga tgaagcgcat cacctggtgt
     4201 ggagcgaaga tgcgccaagc cgtgaatatc aggccattga acaactggca gagcacgtgc
     4261 cgggcgttct gctgctgacc gcgaccccgg aacagctggg gatggaaagc cacttcgccc
     4321 gtctgcgtct gctggacccg aaccgtttcc acgattttgc gcagttcgtt gaagagcaga
     4381 aaaattatcg tccggttgcg gacgccgttg ccatgctgct ggcaggtaac aaactgagca
     4441 atgacgaact gaacatgctc ggcgagatga tcggcgagca ggatatcgag ccgctgttgc
     4501 aggcagcaaa cagcgacagc gaagatgccc agagcgcccg tcaggagctg gtttcgatgc
     4561 tgatggatcg ccacggcacc agccgcgtgc tgttccgtaa cacgcgtaac ggtgtgaaag
     4621 gattcccgaa acgcgagctg cacaccatta agctgccgct accgacgcag tatcagacgg
     4681 ctattaaagt ctccggcatt atgggcgcac gtaaaagtgc ggaagatcgt gctcgcgata
     4741 tgctctaccc ggagcgtatt tatcaggaat ttgaaggtga taacgccacc tggtggaact
     4801 tcgatccgcg cgttgagtgg ctgatgggct acctgaccag ccatcgctct cagaaagtgc
     4861 tggtgatctg cgccaaagct gccactgcgc tgcaactgga gcaggtactg cgcgaacgtg
     4921 aaggtattcg cgctgcggtg ttccacgaag gtatgtcgat tatcgaacgt gaccgcgctg
     4981 ccgcctggtt tgccgaagaa gacaccggcg cacaggtact gctgtgctca gaaatcggtt
     5041 ctgaaggacg taacttccag ttcgccagcc acatggtgat gtttgacctg ccattcaacc
     5101 cggatctact ggagcagcgt attggtcgtc tggatcgtat cggccaggcg cacgatattc
     5161 agatccatgt gccttatctg gagaaaaccg ctcagtcggt gctggtgcgc tggtatcacg
     5221 aaggtctgga tgcatttgag cacacctgcc cgaccggacg cactatttac gatagcgtat
     5281 acaacgatct gattaactat ctggcttcac cggatcaaac cgaaggcttt gacgatctga
     5341 tcaaaaactg ccgcgagcaa catgaagcgc tgaaagcaca gctggaacag ggtcgtgacc
     5401 gcctgctgga aatccactcc aacggtggcg aaaaagccca ggcactggca gaaagcattg
     5461 aagagcagga tgacgatacc aacctgatcg ccttcgccat gaacctgttc gatattatcg
     5521 gtatcaatca ggacgatcgc ggcgacaaca tgatcgtgct gacgccgtcc gatcatatgc
     5581 tggtgccgga cttccctggc ctgtcggaag atggcatcac catcaccttt gatcgtgaag
     5641 tggcgctggc gcgtgaagat gcacagttta ttacctggga gcatccgctg atccgcaacg
     5701 gtctggatct gatcctttct ggcgataccg gtagcagcac gatttcactg ttaaaaaaca
     5761 aagcgttgcc ggtaggtacg ctgttggtgg aactgattta tgtggttgaa gcccaggctc
     5821 cgaagcagtt gcagctcaac cgcttcctgc caccgacgcc ggtacgtatg ctgctggata
     5881 aaaacggcaa caacctggcg gcgcaggtag agtttgaaac ctttaaccgc cagcttaacg
     5941 cggttaaccg tcacaccggc agcaaactgg ttaacgccgt gcagcaggat gttcacgcta
     6001 tccttcaact gggtgaagcg cagatcgaga aatctgcccg tgcattgatt gatgcagcgc
     6061 gtaacgaagc cgacgaaaaa ctgtctgccg agctgtctcg tctggaagct ctgcgtgcag
     6121 tgaacccgaa cattcgtgac gacgaactga ccgccattga gagcaaccgt cagcaggtaa
     6181 tggaaagcct ggatcaggca ggttggcgtc tggatgccct gcgtttgatc gttgtaacgc
     6241 atcagtaacg gagccgaaaa tggggatgga aaactacaat ccaccgcagg aaccctggtt
     6301 ggttatcctg tatcaggatg accatattat ggtggtcaac aagccgagcg gtttgttgtc
     6361 agtgccgggt cgtctggaag agcacaaaga cagcgtgatg acgcgcattc agcgtgatta
     6421 tccgcaggca gaatcggtgc atcgtctgga tatggctacc agcggcgtga ttgtagtggc
     6481 gctgaccaaa gccgcggagc gggagttaaa acgccagttc cgcgagcgcg agccgaaaaa
     6541 gcagtatgtg gcccgcgtct gggggcatcc atcccccgca gaaggtctgg tggatctgcc
     6601 gctgatttgc gactggccaa accgcccgaa acagaaagtc tgttacgaaa cgggtaaacc
     6661 tgcgcagacg gaatatgaag tggtggagta tgcggcggat aacacggcaa gagtggtgtt
     6721 aaaaccgatt accgggcgtt cgcatcaatt gcgtgtgcat atgctggcgc tgggtcatcc
     6781 gattctcggc gatcgttttt atgcatcacc agaagcgaga gcgatggcac cacgtttgtt
     6841 gctacatgca gagatgttga cgattaccca tccggcgtat ggcaatagta tgacgtttaa
     6901 agcgccagcg gatttttaac ctttcctgta cgtttatacc ctcatcctaa gggctgcctc
     6961 ttgtacataa atccccgagt ccggggattt tttgtttctg ccaaactgct ttcagttgtt
     7021 gcgtgtggct acgctttcca ttcggtaatt cccttcctgc tccacagcga atttttgaac
     7081 tttttcttca cccgttgacc gtctcttata tttcatttta acgggtctgt tatggtcctt
     7141 tctgattgtt attcatgggc taattagcag tctggttggc gatgcccatc tcggtgatcc
     7201 gtgtcctgca cgacgccttg cgtcactagc ctcttctcta gctcatcatg caggtctttc
     7261 taattgtgaa atcatcccac gctactgcta aggttgaagg ggcgttccag ccccttcaac
     7321 cttagcttat tctggctcat tcaataattg cgttgtcagt aatttgttca gcagtacttt
     7381 tttagtagca acttcttcag tagcaactcc tttagtatca atttttttgg gggggatttt
     7441 attaataata attacctcat catataggga ggtagcaccg ttcacggtag caccgtccag
     7501 gatagcaccg tccggggtag caccgtccag gatagcaccg tccggggtag caccgtccgg
     7561 ggtagcaccg cccaggttag cattccaccc aggtctctca taaaggatat cattgctacc
     7621 tttcattgtt tttttaccaa ggtaacaatc cctcatgtca acgccgggaa ggtaagcctt
     7681 tctaagatca acgcccaagt taccttggcc cttatgcagc tgcaacgtct gagtacatat
     7741 cttattcttt tcaatgaaaa aagtgacact taactcgata tccccgaagg tctgggcgac
     7801 ccagcgcata ttgccctttg cgaccaactc atccggattt tttgcgcatg ttttaagttt
     7861 attgaataat tccaggctat tgataaactt ttctctctca ttctcgttga tagccccagt
     7921 aaagtattct gaggcgttga tgttgccagt ctggttattc acgaaattga acagaagttt
     7981 ataagcctca gtctgtttat ctgaccagaa cagatggcgt aacgtctccc acaagcgttg
     8041 aaagatattc atcttcacgt ccatcttgtc cccgctcacc atcttataaa tatcgttctt
     8101 gctcatattt aaaagtgtaa ccggcatgcc tggaactgat actttcatgg taatagcctc
     8161 gcattgagtt aaaaactcat gatgcgcgtt ctgaataaat atactttcaa aaatcgctca
     8221 ttcaggtatg tgttttttat ttttaagacg taaaaatata attccgctcg tcgtaaagct
     8281 ctcaacctta agcagggtca acgcgataaa acctacagaa cccctcccgt aaaccgtgca
     8341 ttgagcctgt ccaccattct gagtaaacgc cttttctcaa agaagtgacc gccagggcgg
     8401 ccacctttaa tcgtgggcag ttactcagca tcatttacag ggtcatttaa accctttctg
     8461 ctgctttatc agctcatatg cctgctgaat ttcctgcgct ttctgcttcg ccatctccat
     8521 catctcaggc ggcaaacctt tcgccaccag cttatcggga tggtgttcac tcatcagctt
     8581 acggtaggca cgtttgatgg tggtcgcatc atccgtcggc ttcacgccca gcacattaca
     8641 ggcatcttcc agcgttgggc cacgctgcgc ttgctgccag ttaccaccgc cagtttgctg
     8701 ctgataaccg ccgccaaact gtgcaccgcc ctgcatcatg cgcaaaaact ggtcaaactg
     8761 agcgcgggag atccctaatt cttctgcaat gacatacagc accgcccgtt cattcgggtg
     8821 cagtgaacca tcagcaaacg ccgcctgaat ctggatctcc agaaacatac gaattaagtc
     8881 aaaacgacca aagcagacac tgcgaaactg gcgcatcttt tcgcgcagcg ggtaattgtc
     8941 tgattttccc acccggaacg cattttgcgc cgcagtacgg gaagcgccat gaagattcat
     9001 tcggtccatc aactggctgg cgatatgaat atcagcctcc gtgacgcgac ctttggattt
     9061 ggttaaatgc cccatcactt caaaagtggt ggcaaaaaac agcgcctgac gctcacgctg
     9121 gttggcgaac cacgccattt tacggctacg ggctttatca aacatatggc caattaacag
     9181 gcctaacact acgccccaaa agccgccgcc catcagtaag gccacggcca cgccaatgat
     9241 ttttccccaa tactgcatat attccccaaa tcgacacacg gatatcaggg ctatctccca
     9301 caatataaag gtgcttttac cgttttccgg ctgcggtcaa ttgtgggaca tcgcctataa
     9361 tttgcattat catacctgtc attcaatgcc gtgcctaaca ccactgacgc tattcggaca
     9421 ggattaacac tagcgtagag atgacgagta cgttagtctc tgaccgtttg tcacgcgcaa
     9481 cgttaccgat gatggaacaa taaaatcaac gtatgaaaaa acgtatcccc actctcctgg
     9541 ccaccatgat tgccaccgcc ctttatagtc aacagggact ggcagccgac ctcgcctcac
     9601 agtgcatgtt gggcgtgcca agctatgacc gtcctctggt acagggcgat accaatgact
     9661 tacccgtgac tatcaatgct gaccacgcga aaggggacta cccggatgac gccgtgttta
     9721 ctggcagcgt ggatatcatg cagggtaaca gccgtctgca ggccgacgaa gtgcagctcc
     9781 atcaaaaaga ggcaccagga caaccggagc cggtacgtac cgttgatgcg ctcggtaatg
     9841 tccattacga cgataaccag gtgatcctca aagggccgaa aggctgggcg aatctgaaca
     9901 ccaaagatac caacgtctgg gaaggtgatt accagatggt gggtcgccag ggtcgcggta
     9961 aagcggacct gatgaaacaa cgtggcgaaa accgctatac cattctggat aacggtagct
    10021 ttacctcctg tctgccgggt tctgacacct ggagcgtggt aggtagcgaa attattcatg
    10081 accgcgaaga acaagttgcg gagatctgga acgcccgctt taaggtgggt ccggtaccga
    10141 tcttttatag cccctatttg cagttgccgg tgggtgacaa acgtcgctct ggtttcttga
    10201 tcccgaacgc caagtacacc accaccaact actttgagtt ctacctgcca tattactgga
    10261 acatcgcgcc aaatatggat gccaccatca cgccgcatta tatgcatcgt cgtggcaaca
    10321 tcatgtggga gaacgaattc cgctacctct cccaggcggg cgctggcttg atggaactgg
    10381 actatctgcc ttcagataaa gtctatgaag atgaacaccc gaacgatgac agttcacgtc
    10441 gttggttatt ctactggaac cactccgggg tcatggatca ggtgtggcgt ttcaacgtcg
    10501 actacaccaa ggtcagcgat cctagctact tcaatgattt cgataacaag tacggttcca
    10561 gtactgacgg ctacgcaacg caaaaattca gcgttggcta tgcggtgcaa aacttcaatg
    10621 ccaccgtttc aaccaagcag ttccaggttt tcagcgaaca gaacaccagt agctactcgg
    10681 cagagccgca gttagacgtt aattactacc agaatgatgt tggtccgttt gatacgcgta
    10741 tttacggcca ggcagtgcac tttgttaaca ccagagacga catgcctgaa gcaacccgtg
    10801 ttcacctgga accgaccatc aatttgccgc tctctaataa ctggggcagc atcaataccg
    10861 aagcgaagtt gctggcaacc cattatcagc aaaccaatct tgactggtat aactccagaa
    10921 acacgaccaa gctggacgaa tccgttaacc gcgtaatgcc gcaattcaaa gttgacggca
    10981 aaatggtctt tgaacgcgat atggaaatgc tggctccggg ttatacccaa acgctggaac
    11041 cgcgcgcgca gtatttgtac gtgccgtatc gcgatcagag cgacatctat aactacgact
    11101 cgtctctgct gcaatctgac tactctggcc tgttccggga ccggacttac ggcggtcttg
    11161 accgtattgc ctccgctaac caggtgacga ccggtgtcac atctcgcata tatgatgatg
    11221 ctgccgttga acgttttaat atttccgttg gtcaaatcta ctatttcacg gagtctcgca
    11281 ctggcgatga caacataaca tgggagaatg acgacaaaac gggttcactg gtgtgggcag
    11341 gcgatactta ctggcgtatc tccgagcgtt ggggattgcg tggcgggatt cagtacgata
    11401 cacgtctgga taacgtagcg accagtaact ccagcattga ataccgtcgg gatgaagacc
    11461 gtctggtaca gctgaattac cgttacgcca gcccggaata tattcaggct acgctgccta
    11521 agtactattc cactgctgag caatataaga atggtatttc gcagataggt gctgtcgcca
    11581 gctggccaat tgccgatcgt tggtccattg ttggggccta ctactacgac accaatgcta
    11641 acaagcaagc cgactctatg ttaggtgtgc aatacagctc ctgctgctat gcaattcgcg
    11701 tcggttacga gcggaagctg aacggttggg ataacgataa acaacatgcg gtatatgaca
    11761 acgcaatcgg ctttaacatc gaacttcgcg gcctgagctc caactacggt ctgggtacgc
    11821 aagagatgct gcgttcgaac attctgccgt atcaaaacac tttgtgattt gttgatttac
    11881 cacgtaatcc gcagtgcggt taattgaaat ggaaaaagta tgaagaactg gaaaacgctg
    11941 cttctcggta tcgccatgat cgcgaatacc agtttcgctg ccccccaggt agtcgataaa
    12001 gtcgcagccg tcgtcaataa cggcgtcgtg ctggaaagcg acgttgatgg attaatgcag
    12061 tcggtaaaac tgaacgctgc tcaggcaagg cagcaacttc ctgatgacgc gacgctgcgc
    12121 caccaaatca tggaacgttt gatcatggat caaatcatcc tgcagatggg gcagaaaatg
    12181 ggagtgaaaa tctccgatga gcagctggat caggcgattg ctaacatcgc gaaacagaac
    12241 aacatgacgc tggatcagat gcgcagccgt ctggcttacg atggactgaa ctacaacacc
    12301 tatcgtaacc agatccgcaa agagatgatt atctctgaag tgcgtaacaa cgaggtgcgt
    12361 cgtcgcatca ccatcctgcc gcaggaagtc gaatccctgg cgcagcaggt gggtaaccaa
    12421 aacgacgcca gcactgagct gaacctgagc cacatcctga tcccgctgcc ggaaaacccg
    12481 acctctgatc aggtgaacga agcggaaagc caggcgcgcg ccattgtcga tcaggcgcgt
    12541 aacggcgctg atttcggtaa gctggcgatt gctcattctg ccgaccagca ggcgctgaac
    12601 ggcggccaga tgggctgggg ccgtattcag gagttgcccg ggatcttcgc ccaggcatta
    12661 agcaccgcga agaaaggcga cattgttggc ccgattcgtt ccggcgttgg cttccatatt
    12721 ctgaaagtta acgacctgcg cggcgaaagc aaaaatatct cggtgaccga agttcatgct
    12781 cgccatattc tgctgaaacc gtcgccgatc atgactgacg aacaggcccg tgtgaaactg
    12841 gaacagattg ctgctgatat caagagtggt aaaacgactt ttgctgccgc agcgaaagag
    12901 ttctctcagg atccaggctc tgctaaccag ggcggcgatc tcggctgggc tacaccagat
    12961 attttcgatc cggccttccg tgacgccctg actcgcctga acaaaggtca aatgagtgca
    13021 ccggttcact cttcattcgg ctggcattta atcgaactgc tggatacccg taatgtcgat
    13081 aaaaccgacg ctgcgcagaa agatcgtgca taccgcatgc tgatgaaccg taagttctcg
    13141 gaagaagcag caagctggat gcaggaacaa cgtgccagcg cctacgttaa aatcctgagc
    13201 aactaatggt taaaacccaa cgtgttgtga tcactcccgg cgagcccgcc gggattggcc
    13261 cggacttagt tgtccagctt gcacagcgtg agtggccggt cgaactggtt gtttgtgccg
    13321 atgccactct ccttaccaac cgggcagcga tgctcggttt gccgctcacc ctccgccctt
    13381 attcccccaa ctcccctgca caaccgcaaa ctgcgggcac attaacgcta cttcctgtcg
    13441 cgctacgtgc acctgtcact gcggggcagt tagcggttga aaatgggcat tatgtggtgg
    13501 aaacgctggc gcgagcgtgc gatggttgtc tgaacggcga atttgccgcg ctgatcacag
    13561 gtccggtgca taaaggcgtt attaacgacg ctggcattcc ttttaccggt cataccgagt
    13621 ttttcgaaga gcgttcgcag gcgaaaaagg tggtgatgat gctggcgacc gaagaacttc
    13681 gcgtggcgct ggcaacgacg catttaccgc tgcgcgatat cgcagacgct atcacccctg
    13741 cacttttgca cgaagtgatt gctattttgc atcacgattt gcggaccaaa tttggtattg
    13801 ccgaaccgcg cattctggtc tgcgggctga atccgcacgc gggcgaaggc ggtcatatgg
    13861 gtacggaaga gatagacacc attattccgg tgctcaatga gctgcgggcg caggggatga
    13921 aactcaacgg gccgctgcct gccgataccc tgtttcagcc gaaatatctt gataacgccg
    13981 acgccgtgct ggcgatgtac cacgatcagg gtcttcccgt gctaaaatac cagggcttcg
    14041 ggcgcggtgt gaacattacg ctgggcctgc cctttattcg cacatcagtg gaccacggca
    14101 ccgcgcttga actggcggga cgtggcaaag ccgatgtcgg cagttttatt acggcgctta
    14161 atctcgccat caaaatgatt gttaacaccc aatgaataat cgagtccacc agggccactt
    14221 agcccgtaaa cgcttcgggc aaaactttct caacgatcag ttcgtgatcg acagtattgt
    14281 gtctgccatt aacccgcaaa agggccaggc gatggtcgaa atcggccccg gtctggcggc
    14341 attgaccgaa ccggtcggcg aacgtctgga ccagctgacg gtcatcgaac ttgaccgcga
    14401 tctggcggca cgtctgcaaa cgcatccatt cttaggcccg aaactgacga tttatcagca
    14461 ggatgcgatg acctttaact ttggtgaact ggccgagaaa atgggtcagc cgctgcgtgt
    14521 tttcggcaac ctgccttata acatctccac gccgttgatg ttccatctgt ttagctatac
    14581 tgatgccatt gccgacatgc actttatgtt gcaaaaagag gtggtgaatc gtctggttgc
    14641 aggaccgaac agcaaagcgt atggtcgatt aagcgtcatg gcgcaatact attgcaatgt
    14701 gatcccggta ctggaagtac cgccgtcagc ctttacacca ccacccaaag tggattccgc
    14761 cgtcgtgcgc ctggttcctc atgcaacgat gcctcacccg gttaaagatg ttcgtgtgtt
    14821 gagccgcatc accaccgaag cctttaacca gcgtcgtaaa accattcgta acagcctcgg
    14881 caacctgttt agcgtcgagg tgttaacggg aatggggatc gacccggcga tgcgagcgga
    14941 aaatatctct gtcgcgcaat attgccagat ggcgaactat ctggcggaga acgcgccttt
    15001 gcaggagagt taacgatgat caattcgccc cgagtgtgta ttcaggttca aagcgtctac
    15061 attgaggctc aatcttcacc tgataatgaa cgttacgttt ttgcttatac cgtaaccata
    15121 cgcaatctgg ggcgagcgcc agtgcagttg ttggggcgtt actggctgat caccaatggc
    15181 aatggccgtg aaaccgaagt ccagggcgaa ggagtggttg gcgtccagcc acttatcgcg
    15241 cctggcgaag agtaccagta caccagcggt gcaatcattg aaaccccgct gggcaccatg
    15301 cagggtcact acgaaatgat cgatgaaaat ggcgtccctt tcagcatcga cattcccgta
    15361 ttccgactcg ccgttcccac actcattcat taaaagaata tggcgacata ccttattggc
    15421 gacgttcatg gttgttacga tgaactgatc gcattgctgc ataaagtaga atttacccct
    15481 gggaaagata ccctctggct gacgggcgat ctggtcgcgc gcgggccggg ttcgctggat
    15541 gttctgcgct atgtgaaatc cttaggcgac agcgtacgtc tggtgctggg caatcacgat
    15601 ctgcatctgc tggcggtatt tgccgggatc agccgcaata aaccgaaaga tcgcctgaca
    15661 ccgctgctgg aagcgccgga tgccgacgag ctgcttaact ggctgcggcg ccagcctctg
    15721 ctgcaaatcg acgaagagaa aaagctggtg atggcccacg cagggatcac gccgcagtgg
    15781 gatctgcaga ccgccaaaga gtgcgcacgc gatgtagaag cggtgctatc gagtgactcc
    15841 tatcccttct ttcttgatgc catgtacggc gatatgccaa ataactggtc accggaattg
    15901 cgggggctgg gaagactgcg ttttatcacc aacgctttta cccgtatgcg tttttgcttc
    15961 ccgaacggtc aactggatat gtacagcaaa gaatcgccgg aagaggcccc tgccccactg
    16021 aaaccgtggt ttgcgattcc tggccctgtc gctgaagaat acagcatcgc ctttggtcac
    16081 tgggcatcgc tggagggcaa aggtacgccg gaaggtatat acgcgctgga taccggctgc
    16141 tgctggggtg gtacattaac ctgcctgcgc tgggaagata aacagtattt tgtccagccg
    16201 tcgaaccggc ataaggattt gggcgaagcg gcggcgtctt aaacacagcc tgatatagga
    16261 aggccggata agacgcgacc ggcgtcgcat ccggcgctag ccgtaaattc tatacaaaat
    16321 taccgccgct ccagaatctc aaagcaatag ctgtgagagt tctgcgcatc agcatcgtgg
    16381 aattcgctga ataccgattc ccagtcatcc ggctcgtaat ccgggaaatg ggtgtcgcct
    16441 tccacttctg cgtcgatatg cgtcagatac agtttttgcg cttttggcaa gaactgttca
    16501 taaacgcgac cgccgccaat caccatgatt tctggtacgt caccacacgc cgcgatggct
    16561 tcatccaccg acttcaccca cgttacgcga tcgtccgtac ccggttgact gctgaggata
    16621 atatttttgc gtcctggcaa cggacgaccg attgattccc aggtatggcg gcccataatc
    16681 acgggtttat ttaaggtgtt gcgtttaaac caggcgagat cggcaggcag gttccacggc
    16741 atggcgtttt ccatgccgat aacgcgatct accgctaacg ccgcaatcag actgatcatt
    16801 gagatttccc gataaaaaaa attgtcgcca ctatacgtaa agcgtaaacc gtcgtcgact
    16861 ggtgcgagga tgatgttgag gaaaatttta tattctgctg gcgagtccac gctctctccc
    16921 tggactcgcc gcattacaat gaaacaaaaa caaacagtta gctgtaaagt gtgatttacg
    16981 tcactcttta ttaggatgag ggtttcgttt ccggttcatc cgccatgttg ccggtatgtt
    17041 taccttcttc ggttccctgc cagccatgtc gttgaattaa tgacagatgt tcgcggtcct
    17101 cggtaatgat ctcacttaac atcgcgctgg tgcgtttata gaccgccgcg cgggctttgg
    17161 tgtcgttctc aaccattgcc atctcttcca ccatctgaat attaaagcgg cggaacacat
    17221 cggcacgttc tcgcgcttca tacggcccca gacctaaact ttccagtgcc agacgcccgg
    17281 ttttcagcgc accttcgaag gtttcacgct ccggcttttc aacgcctgcc tgacgcaaac
    17341 gaatgtagtg gtcgacatcg cgggcgcggg caataatctg caaatgcggg aaatgttctt
    17401 tcaccatctc tgtcagttgc aggttggttt gcggatcgtc gatggcgtta atcagcactt
    17461 ccgctttcgc cgctccggca gattccagta aatccatccg cgtggcatcg ccataaaaca
    17521 ctttcatacc aaatttacgc aaggtttcga tatggtccgg atcgtgatcg agtaccacca
    17581 ttttcacccc gctggagagc agtaaacgtc cggtaatctg cccaaaacga ccgaatccgg
    17641 cgataatcac gcgcggctgt tcttcgtcga tctcatcggc ttcacgcgct tcctcagtag
    17701 aagattgctc aaggcgattg aggatcacca gcagaatcgg cgttgctgcc atcgacagcg
    17761 ccaccgccag ggtcagcgat ttcgcccact ccggctccag cacattcgcc atctgcgccg
    17821 cgccaaatac cacaaaggca aactcactgc cctgccctaa caacaccgca aaccaacgac
    17881 gctgtttatt tggcacttgc aacggtcggg caatcagcca cagcatggcg attttgatga
    17941 tgaggaaacc gagcagcaaa atgacaatgc gcaatgggtt ttcaagcagc gtgccaaagt
    18001 ctatcgacat gccaacaccg atgaaaaaca gccccaacag caaaccttta aatggttcga
    18061 tatcgctctc cagcgcatga cggtattccg agcttgccag cagtacgccc gccagaaacg
    18121 cgcccatcgc catcgacaag ccgacctctt ccagcagcaa accaaagcca aacacgagga
    18181 ataacgccac ggcactaaac acttcccgca agccagagcg ggctacaaaa cgcagcgccg
    18241 gacgcgtgac atagcgcccc agcaatacca ccagcaccag cgcacccgcc acttttaacg
    18301 ccgagagagc aaatgcgccc atcgtcgtcg aggcactgct cgttgccagt agcggaatca
    18361 tcgccaccag cgggatcgcc gcgatatcct ggaacagcag caccgcaaag gcactgcgac
    18421 ccatttgcgt caccatcaga ttgcgttcat tcatcgcctg catggcaatc gccgtagagg
    18481 agagcgccag cgtcatgccg atcaattccg cgacctgcca gcgcagccca agtaacatgc
    18541 agaacagccc cagcaggccg ccgcaaatca ccatctgcaa tgcgccacag ccgaacactg
    18601 ccgcacgcag cttccacagc ctttgtggat cgagttcgag gccgataata aacagcatca
    18661 gcaccacccc aatctcggca aagtgcagaa tagattcggc atcggtcacc agtcgcagcc
    18721 cccacgggcc aataatgcag ccggcgatca ggtagccaag taccgatccc agaccaagac
    18781 gtaccgcaat gggtacaatc agcgctgccg aaccgagata aatcagcgcc tgaatcagcg
    18841 tatggctatc catgatgggc ctcctgccat tccagcagac gttgcttata gtgacgcgcc
    18901 tgcccttcga gggtttcgtc gtcacaaata aaggtgcagt gcatggcaaa cggtggcagc
    18961 cagttcagcc cgcagtagat tgccgtcgcc tgtagcggct gcgacagcac atcaaagccc
    19021 ggatgcgcac caatttcaaa atggctttcc ccgccgccgg tcgtcaccgc ccacagcaaa
    19081 tgtttgccat gcagcgccgt gccgccatga ccgtaagccc agccgtggga gaaaacttta
    19141 tcgatccaaa gtttgaggag cggaggaatg ctgtaccact gcatcggatg ctgccagacg
    19201 atcagatcgg cgcgagacaa cgcctcctgc tcggcggcaa tatcgatatt gaagtcagga
    19261 tagagttgat aaagagagcg aatttcgacg ccttccagcg tccttgcctg ttcaagcatc
    19321 cgtttattcg catgggaatg atgcggatac ggatgcgcat aaattataag aatcataggt
    19381 agcccgcgtg attacgcctt tgttttccca caaagtgtag tcatatattc acgcggctta
    19441 tagtcaataa tattgattca gaaaagagag aaatctgaac aatttacccc attctctgcc
    19501 cgcggatcgt catattgctg gtctgcgcca gtgacatccc tcgagtctcc ggggcaaacg
    19561 ctacggaaat caacaagcca aacagcgaga tacccgcccc cattagcatc gtgttactga
    19621 taccgtaatt attgataaag atcggtagtg cccaggtcga aacaatggtg ccaatacgac
    19681 ttaaggacat aatcacgccc acggcagagg cgcggatatc tgtcgggaag agttcattag
    19741 gatagagcca ctgcaaatta cccggcccgc cagagaaaaa ggcatacacc gcaaaggcca
    19801 tcactaccag ccagatcccc atatccggga ttagccccaa aaccgccagc gccagcgtca
    19861 tcatggcaaa gctgccaatc aacaatggac gccgtccggc agtgtttaac cacagcatcg
    19921 gcggaataca gccgagcata aagaacaggc taatcaccac attccctagt gccgcgtttt
    19981 tgccaacccc caatcccaac aaaccaacga tttgcgggcc aaaggtgtaa atggcgaaca
    20041 ttgggatcac ctggcaggtc cagatggcgg caacaaacag aacaaaagga aaatggcggc
    20101 gattaaacag atcgcgaaaa cgggtttgct gcggctgctc ttcatcgaaa gccaccggtt
    20161 cgccaaacag tttgatcatc atctcttcgc actcttttac tcgccctttg cgtaataacc
    20221 agcggggaga ttcaggcagt tcgaatcgac caatcaaaat caacaaacag gggatcgccg
    20281 cgctacccag catccagcgc cagccgcctt ccacatcata aagccagtag ccgaccagat
    20341 cggcacaggt cgcgccgaca taccacatcg cggcaataaa gctgatggaa aacgcccgct
    20401 gacgggtact ggagaactcg gtgatcattg aggtggcgat gggataatct gcaccgatga
    20461 caatgccgat aagtacccgc atcaccaaca gttcgacggg ggatgaaaca aacatcgtcg
    20521 ccaccgatat cacgccgatg gcgatgatat caatgaggaa cattttgcgc cgtccgactt
    20581 tatcggaaat ataaccaaac agcgatgtgc caacgaacag cccggcgagc gttcccgcgc
    20641 ccagcaagcc aatccagtca gcgtccagtt tcagcgccgg cgtcagttgc tccagcgcca
    20701 cgccaatcat taccagtaca taaccatcca gaaacggacc accgcttccc cacagcaaaa
    20761 tgcggcggtg aatagaggag aatttgagat cgtcaaagtt tctggacggt tgcatggtta
    20821 ttcctgtttt ttgcaatgag agtcagtgcg gcgttacgta tcaaaccaac atcagccgta
    20881 acggaactcc acaccaaagg tgccgcgcgg gtattcccac tgttccagcg ccgaccccag
    20941 ccccagaatg cgacaggtgc cgcactccag acatccggcg taatcgaagc gcacactgcc
    21001 gtcatcctgc ttcttgtaca gacctgcggg gcacgctttc accagcagct ccagcgcctg
    21061 tttatcagca tcggccttca caacaatgtg cggatgctct tcatcgacat tgaatttatt
    21121 gacgcccagt ttgacgtcca cattgacggg agaagtcata aaacggtcac tcctttcatg
    21181 ccatccttga ttagattgat gaagcccact ttcttgccgt ggcggaggat tttcttgcgc
    21241 atcagttccg gcgcgctgcc atcaatggtg aacaggtcac gcgccacacc caccgccagc
    21301 tccgggtagc cgctaaacat gcgtgggtta tcaaggaacg ccggtagttt ctggtacata
    21361 cgcatatcgc gcagcggacc actctcaaga tgctgacgat attccgccag tttttgctta
    21421 ctgaaatcgt cgcttttcat cgctgaaagc acggtttttg ctgcggcttc cccggcggca
    21481 atcgccagat ccataccgcg aatggtaaaa ccgaggttca tacacattcc ggcggcatca
    21541 ccggcaatca atacgccgtc accaaccaac tccggcagca tgttgatgcc tgcttccggc
    21601 actacgtgag cggaatattc caccagcttg ccgcccgcga tcagcggtgc aacggccgga
    21661 tgctgtttga aatcttccag catttgcggc accgattttt tcgcgtcatg cagatgatgc
    21721 aaaccacaaa ccagccccag cgacagggtg ttttcattgg tataaaggaa gccgccgccc
    21781 atcaggccat cggtgggtga tcccgcaaac aggcaagccg ccccctgatt accctgcaac
    21841 tgaaaacggt cttcaataac cgacttcggt aactcgatca gttccttcac gccaaccgcc
    21901 acatccgtcg gtttgacgcg ttttgccatc cccaattttt cggcaaggat ggagttcacc
    21961 ccatcagcaa ggatcaccgt tttcgcttca atcacatcgc catcggcttc tacaccgacg
    22021 actttgccat cgcgctgtac gaggttatcg acgcggatcc cggtaattaa ctgcgcgccc
    22081 gcttcttcgg cctgctccat cagccaggca tcaaatttac tgcgcaaaac ggagtaagaa
    22141 cgctgggatg gcgaggtttc gtcaccattg cagtagtcca tagtcatcgc tgacttttcc
    22201 gtcataaacg cgagtttttc atgggtgatc aggcgttcta cgggggcgga gtcggcgaaa
    22261 ccaggaataa tgtgttccag actgtgggca tagagacgcc cgccggtgac gttcttggca
    22321 cctgcggaat tgccacgctc gataactaac acttgcgcac cttcgcgggc gagcaccagt
    22381 gcggcaaccg aaccggcaag ccctgcaccg acgatgatgg cgtcaaagat atcttcggac
    22441 ataagagctc cctgtcagcg gcagggccaa aatgcagccc tgccagagtg gatcaacgcg
    22501 ctaaagctgc ggtcagcgcc ggaaggatct tcacggcgtc gccaacaatg ccgtaatccg
    22561 cgtactggaa gatcggcgca tttttatctt tattgatggc gaaaatggtt tgcgacgcgt
    22621 tagcgccaac catgtgctgg atctgcccgg agatccccac cgccaagtac agttcaggtt
    22681 tcagcatcag gttggagata ccgacatagc gttcgtgctc catccatttt tcgttttccg
    22741 ccaccggacg agaacaggcc aactccgcac ctatcgcctt gcaaagctgt tctgccagcg
    22801 caatgttctc tttgctgcca ataccgcgac cgacgctgac caccagacgg gctttgtcga
    22861 gatcgacgct gttgctctgg cgcgcctggg ttgccgtgcg ggtaatcgcc acagccggag
    22921 cctgccactc cacggtgtgc gtttcgccag tgcgtgacgc gtctggctga gccgcatcga
    22981 acgtgccgct gctgatggtc agtaccgcat acggcgtggc aatgcgttct tcgccaatcg
    23041 ccagaccacc gtaaaccatg tgtttcactg tcgctttacc gtcctgtacg ctgacggtgc
    23101 tggcatcgtt agacaccgcc gctttaaggc gataacccag ttttgccgcc agtaatttgc
    23161 cgcgacgggt gtttggcagc agcaccaggc cgtctgcgcc gtgctggcga atagtgtcag
    23221 ccatgacacc ggcgtaatct tcgatcatcc gatcgtccgg tttgccgttt aatttccaga
    23281 catgattagc gccgagctgg attgcctgtg cgccgtcggc atcattgagg acaaaggtgt
    23341 tgatttgatt agctaaagcc tgcgcaccgt tcatcagttc cggcagacga gaaggggtat
    23401 cgctgaatac ccagacttga gaaaacgtgt tcatagcatc ccctgtaatt aaatgacttt
    23461 gcgaagattt tcagcaaatg cggcgatctg ttcttcgccg tcgccttcaa tcacgatgcg
    23521 ctgacgttcg cgctgtttcg gcgcggcaac ctgttgttct gaccaggctg cctctgcgtt
    23581 aaaaccaata tccgccgccg accatacctg gacgggcttt ttcgccgcgc cgagaatggc
    23641 tttcatcgaa ggaatttgtg gggaattgat atcagtggaa acagcaacaa ccgcaggcag
    23701 cggaatgctt aaggtttcgg tttcatcttc cagttcgcgc tcaacggtga gggtatctgc
    23761 agtcagggag ataattttgc tgacgccgtt aactgccgga atattgagga tttcgcctac
    23821 cagcaaacca acctgctggg cataaaggtc ggaagaacca tcgccacaga ggatcaaatc
    23881 aaagcctgct ttctgggcgg ctgcagccag tgcgctcgcc gtttgttgcg gcagtgcctg
    23941 ctcgaactgg tcatcaatta ccacaatcag ttcatccggg ccgcgcgata acacatcttt
    24001 acgccctttg gcgttggtca gggctttacc gcccacactt aaggctgtca cctgcgcctc
    24061 tgctgcctgt tgctttagct ggcaagccgc ttcaatagcg ttgagatcgt attggcttat
    24121 tttggcatcg gctttgctga agtctaatga accatcagca ttattgaccg caatatcctg
    24181 ttcatcaggc acgcacttat agcaagtaat aatcttcatt gcatctccag aaatcatgaa
    24241 ggaaacgtcg ttcatatcgg tggtgttaat tacagatatc acgcccttta atttggaaat
    24301 aaaactttaa tcaccaatat tgaaaatgtc acacgcagat aaatccaact ttcaatattg
    24361 ttaagttcct caccaatatt gaaaacacgg cgtagcaaaa agaaattttc aatattgttt
    24421 tatggatcac caatattgaa ag
//
LOCUS       DACAOP010000066        24236 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.066, whole genome shotgun sequence.
ACCESSION   DACAOP010000066 DACAOP010000000
VERSION     DACAOP010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24236
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.066"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            181..1716
                     /gene="gadC"
                     /locus_tag="IT892_002942"
     CDS             181..1716
                     /gene="gadC"
                     /locus_tag="IT892_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance gamma-aminobutyrate antiporter
                     GadC"
                     /protein_id="HAP3136134.1"
                     /translation="MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVF
                     FLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIG
                     FIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGF
                     FAGILLPAFILIALAAIYLHSGAPVAIEMDSKTFFPDFSKVGTLVVFVAFILSYMGVE
                     ASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFT
                     VLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNK
                     NGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVL
                     VLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLV
                     VSFLVVLALPFILYAVHDRKGKANTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMND
                     KKH"
     gene            1847..3166
                     /locus_tag="IT892_002943"
     CDS             1847..3166
                     /locus_tag="IT892_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 10 glycosylhydrolase"
                     /protein_id="HAP3136135.1"
                     /translation="MDICSRNKKLTIRRPAILVALALLLCSCKSTPPESMVTPPAGSK
                     PPATTQQSSQPMRGIWLATVSRLDWPPVSSVNISNPTSRARVQQQAMIDKLDHLQRLG
                     INTVFFQVKPDGTALWPSKILPWSDLMTGKIGENPGYDPLQFMLDEAHKRGMKVHAWF
                     NPYRVSVNTKPGTIRELNSTLSQQPASVYVQHRDWIRTSGDRFVLDPGIPEVQDWITS
                     IVAEVVSRYPVDGVQFDDYFYTESPGSRLNDNETYRKYGGAFASKADWRRNNTQQLIA
                     KVSHTIKSIKPGVEFGVSPAGVWRNRSHDPLGSDTRGAAAYDESYADTRRWVEQGLLD
                     YIAPQIYWPFSRSAARYDVLAKWWADVVKPTRTRLYIGIAFYKVGEPSKIEPDWMING
                     GVPELKKQLDLNDAVPEISGTILFREDYLNKPQTQQAVSYLQSRWGS"
     gene            3530..4912
                     /gene="dosC"
                     /locus_tag="IT892_002944"
     CDS             3530..4912
                     /gene="dosC"
                     /locus_tag="IT892_002944"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DosC"
                     /protein_id="HAP3136136.1"
                     /translation="MEMYFKRMKDEWTGLVEQADPPIRAKAAEIAVAHAHYLSIEFYR
                     IVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQVDDVERLIQIQHTVAEVHARIG
                     IPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDS
                     SASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKILLDSDLGSSLPLSQADFG
                     LWFNHKGRHYFSGIAEVGHISRLIQDFDGIFNQTMRNTRNLNNRSLRVKFLLQIRNTV
                     SQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDV
                     DKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLR
                     TAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGR
                     NRVELWKASL"
     gene            4937..7336
                     /gene="dosP"
                     /locus_tag="IT892_002945"
                     /gene_synonym="pdeO"
     CDS             4937..7336
                     /gene="dosP"
                     /locus_tag="IT892_002945"
                     /gene_synonym="pdeO"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416006.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-sensing cyclic-di-GMP phosphodiesterase"
                     /protein_id="HAP3136137.1"
                     /translation="MKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKL
                     WGYKREEVIGNNIDMLIPRDLRPAHPEYIRHNREGGKARVEGMSRELQLEKKDGSKIW
                     TRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQ
                     CNRAFTEMFGYCISEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRT
                     GEKIWIKASISPVYDVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGE
                     IICRNIESVLNESHVSLFALRNGMPIHWASSSHGAEIQNAQSWSATIRQRDGAPAGIL
                     QIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
                     YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRI
                     EGTQFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYDLGKNRDYL
                     LSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIF
                     AETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRS
                     QNIHIPALSVNLSALHFRSNQLSNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFK
                     RIQILRDMGVGLSVDDFGTGFSGLSCLVSLPVTEIKIDKSFVDRCLTEKRILALLEAI
                     TSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMSSVLPLK
                     I"
     gene            7594..8175
                     /gene="ddpX"
                     /locus_tag="IT892_002946"
     CDS             7594..8175
                     /gene="ddpX"
                     /locus_tag="IT892_002946"
                     /EC_number="3.4.13.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine dipeptidase"
                     /protein_id="HAP3136138.1"
                     /translation="MSDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHK
                     DAITALAKSISIAQLSGLQLVIYDAYRPQQAQAMLWQACPDPQYVVDVTVGSNHSRGT
                     AIDLTLRDEHGNILDMGAGFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGIS
                     SEWWHFELPQAASYPLLADQFSCFISPGTQHVS"
     gene            8189..9739
                     /locus_tag="IT892_002947"
     CDS             8189..9739
                     /locus_tag="IT892_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP3136139.1"
                     /translation="MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLD
                     PAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKDN
                     AKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
                     YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYP
                     GNKPNFKRVSVKIIGESASRRLQLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLR
                     VTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMRGPIPEGMWGYDATA
                     MQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGIIVKLEKL
                     ANATMRDRVGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKL
                     LRNALATTDQTQRTRDYQQAQKIVIDDAAYVYLFQKNYQLAMNKEVKGFVFNPMLEQV
                     FNINTMSK"
     gene            9741..10763
                     /locus_tag="IT892_002948"
     CDS             9741..10763
                     /locus_tag="IT892_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3136140.1"
                     /translation="MTFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDR
                     ASDAIVENIRQQLGLDQPLYVQFYRYVSDLFHGDLGTSIRTGRPVLEELRIFFPATLE
                     LAFGALLLALLIGIPLGILSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGH
                     LQILPGGGRLDDWLDPPTHVTGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGI
                     VARQIRSAMLEQLSEDYIRTARASGLPGWYIVLCYALPNALIPSITVLGLALGDLLYG
                     AVLTETVFAWPGMGAWVVTSIQALDFPAVMGFAVVVSFAYVLVNLVVDLLYLWIDPRI
                     GRGGGE"
     gene            10760..11656
                     /locus_tag="IT892_002949"
     CDS             10760..11656
                     /locus_tag="IT892_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D,D-dipeptide ABC transporter permease"
                     /protein_id="HAP3136141.1"
                     /translation="MMLSEETSAVRPQKQTRFNGAKLVWMLKGSPLTVTSAVIIVLML
                     LMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLV
                     VVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAM
                     LAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLINWHILRNSLPPLIVQA
                     SLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAV
                     GFNLFGDGIRDLLDPKAGGKQS"
     gene            11653..12639
                     /locus_tag="IT892_002950"
     CDS             11653..12639
                     /locus_tag="IT892_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP3136142.1"
                     /translation="MTQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGES
                     GSGKSVTAMLIMRLLPTGSYCVHRGQISLLGEDVLNAREKQLRQWRGARVAMIFQEPM
                     TALNPTRRIGLQMMDVIRHHQPISRREARAKAIDLLEEMQIPDAVEVMSRYPFELSGG
                     MRQRVMIALAFSCEPQLIIADEPTTALDVTVQLQVLRLLKHKARASGTAVLFISHDMA
                     VVSQLCDSVYVMYAGSVIESGVTADVIHHPRHPYTIGLLQCAPEHGVPRQLLPAIPGT
                     VPNLTHLPDGCAFRDRCYAAGAQCENVPALTACGDNNQRCACWYPQQEVISV"
     gene            12632..13558
                     /locus_tag="IT892_002951"
     CDS             12632..13558
                     /locus_tag="IT892_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP3136143.1"
                     /translation="MSDTLLTLRDVHINFPARKNWLGKTTEHVHAINGIDLQIRRGET
                     LGIVGESGCGKSSLAQLLMGMLQPSHGQYIRSGSQRIMQMVFQDPLSSLNPRLPVWRI
                     ITEPLWIAKRSSEQQRRALAEELAVQVGIRPEYLDRLPHAFSGGQRQRIAIARALSSQ
                     PDVIVLDEPTSALDISVQAQILNLLVTLQENHGLTYVLISHNVSVIRHMSDRVAVMYL
                     GQIVELGDAQQVLTAPAHPYTRLLLDSLPAIDKPLEEEWALRKTDLPGNRTLPQGCFF
                     YERCPLATHGCEVRQSLAIREDGRELRCWRAL"
     gene            complement(13631..14062)
                     /gene="osmC"
                     /locus_tag="IT892_002952"
     CDS             complement(13631..14062)
                     /gene="osmC"
                     /locus_tag="IT892_002952"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin OsmC"
                     /protein_id="HAP3136144.1"
                     /translation="MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEK
                     GTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKS
                     EVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS"
     gene            14407..14622
                     /gene="bdm"
                     /locus_tag="IT892_002953"
     CDS             14407..14622
                     /gene="bdm"
                     /locus_tag="IT892_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415998.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-dependent modulation protein"
                     /protein_id="HAP3136145.1"
                     /translation="MFTYYQAENSTAEPALVNAIEQGLRAQHGVVTEDDILMELTKWV
                     EASDNDILSDIYQQTINYVVSGQHPTL"
     gene            14724..14861
                     /gene="sra"
                     /locus_tag="IT892_002954"
     CDS             14724..14861
                     /gene="sra"
                     /locus_tag="IT892_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary-phase-induced ribosome-associated
                     protein"
                     /protein_id="HAP3136146.1"
                     /translation="MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAE
                     K"
     gene            15018..16715
                     /locus_tag="IT892_002955"
     CDS             15018..16715
                     /locus_tag="IT892_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415996.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAP3136147.1"
                     /translation="MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLG
                     LLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPV
                     IYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILG
                     LGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRI
                     TDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAA
                     VTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIISQTQREGLSEEAARQKVFM
                     VDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQ
                     TGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVV
                     WKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGMV
                     LPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI"
     gene            16849..17859
                     /gene="adhP"
                     /locus_tag="IT892_002956"
     CDS             16849..17859
                     /gene="adhP"
                     /locus_tag="IT892_002956"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415995.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HAP3136148.1"
                     /translation="MKAAVVTKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVK
                     NGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETL
                     CRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIR
                     PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDA
                     AKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDG
                     IEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDF
                     RH"
     gene            18005..18289
                     /locus_tag="IT892_002957"
     CDS             18005..18289
                     /locus_tag="IT892_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415994.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HAP3136149.1"
                     /translation="MKMANHPRPGDIIQESLDELNVSLREFARAMEIAPSTASRLLTG
                     KAALTPEMAIKLSVVIGSSPQMWLNLQNAWSLAEAEKTVDVSRLRRLVTQ"
     gene            complement(18518..19171)
                     /gene="fdnI"
                     /locus_tag="IT892_002958"
     CDS             complement(18518..19171)
                     /gene="fdnI"
                     /locus_tag="IT892_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit gamma"
                     /protein_id="HAP3136150.1"
                     /translation="MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLT
                     QTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIVEVLKGNEHK
                     VADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYFAQYFPMQVVRYSLLIHAAAGI
                     ILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKHHPRWYREIEKAEAKKESEEGI"
     gene            complement(19164..20048)
                     /gene="fdxH"
                     /locus_tag="IT892_002959"
     CDS             complement(19164..20048)
                     /gene="fdxH"
                     /locus_tag="IT892_002959"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase subunit beta"
                     /protein_id="HAP3136151.1"
                     /translation="MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKA
                     CQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMH
                     CEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKC
                     TLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEG
                     VGGTHVMYVLHHADQPELYHGLPKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHY
                     IGIGPNKEVDDDEEDHHE"
     gene            complement(20061..23108)
                     /gene="fdnG"
                     /locus_tag="IT892_002960"
     CDS             complement(20061..23108)
                     /gene="fdnG"
                     /locus_tag="IT892_002960"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(22521..22523),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HAP3136152.1"
                     /translation="MDVSRRQFFKICAGGMAGTTVAALGFAPKQALAQARNYKLLRAK
                     EIRNTCTYCSVGCGLLMYSLGDGAKNAREAIYHIEGDPDHPVSRGALCPKGAGLLDYV
                     NSENRLRYPEYRAPGSDKWQRISWEEAFSRIAKLMKADRDANFIEKNEQGVTVNRWLS
                     TGMLCASGASNETGMLTQKFARSLGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANVVMVMGGNAAEAHPVGFRWAMEAKNNNDATLIVVDPRFTRTASVADIYAPIR
                     SGTDITFLSGVLRYLIENNKINAEYVKHYTNASLLVRDDFAFEDGLFSGYDAEKRQYD
                     KSSWNYQFDENGYAKRDETLTHPRCVWNLLKEHVSRYTPDVVENICGTPKADFLKVCE
                     VLASTSAPDRTTTFLYALGWTQHTVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSTSLPGYLTLPSEKQVDLQSYLEANTPKATLADQVNYWSNYPKFFVSL
                     MKSFYGDAAQKENNWGYDWLPKWDQTYDVIKYFNMMDEGKVTGYFCQGFNPVASFPDK
                     NKVVSCLSKLKYMVVIDPLVTETSTFWQNHGESNDVDPASIQTEVFRLPSTCFAEEDG
                     SIANSGRWLQWHWKGQDAPGEARNDGEILAGIYHHLRELYQSEGGKGVEPLMKMSWNY
                     KQPHEPQSDEVAKENNGYALEDLYDANGVLIAKKGQLLSSFAHLRDDGTTASSCWIYT
                     GSWTEQGNQMANRDNSDPSGLGNTLGWAWAWPLNRRVLYNRASADINGKPWDPKRMLI
                     QWNGSKWTGNDIPDFGNAAPGTPTGPFIMQPEGMGRLFAINKMAEGPFPEHYEPIETP
                     LGTNPLHPNVVSNPVVRLYEQDALRMGKKEQFPYVGTTYRLTEHFHTWTKHALLNAIA
                     QPEQFVEISETLAAAKGINNGDRVTVSSKRGFIRAVAVVTRRLKPLNVNGQQVETVGI
                     PIHWGFEGVARKGYIANTLTPNVGDANSQTPEYKAFLVNIEKA"
     gene            23340..24221
                     /gene="yddG"
                     /locus_tag="IT892_002961"
     CDS             23340..24221
                     /gene="yddG"
                     /locus_tag="IT892_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415990.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid efflux DMT transporter YddG"
                     /protein_id="HAP3136153.1"
                     /translation="MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLS
                     GLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATHHQAIEVGMVNYLW
                     PSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYF
                     LAFIGAFIWAAYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMIFSTPVMIK
                     LISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGA
                     LMVCGGSLLCWLATRRG"
BASE COUNT         5929 a         6135 c         6130 g         6042 t
ORIGIN      
        1 acagaacagc tttaaacata cctgataacg tttaacggta acggtgtccc gaaacgaacc
       61 cgtttcggga caatttccaa agtctgttca ctggcattag caacggaaaa tattgttctg
      121 aatacgtttc agaacaaaac aggtgcggtt ccgacaggaa taccgtttta gggggataat
      181 atggctacat cagtacagac aggtaaagct aagcagctca cattacttgg attctttgcc
      241 ataacggcat cgatggtaat ggctgtttat gaatacccta ccttcgcaac atcgggcttt
      301 tcattagtct tcttcctgct attaggcggg attttatggt ttattcccgt gggactttgt
      361 gctgcggaaa tggccaccgt cgacggctgg gaagaaggtg gtgtcttcgc ctgggtatca
      421 aatactctgg ggccgagatg gggatttgca gcgatctcat ttggctatct gcaaatcgcc
      481 attggtttta ttccgatgct ctatttcgtg ttaggggcac tctcctacat cctgaaatgg
      541 ccagcgctga atgaagaccc cattaccaaa actattgcag cactcatcat tctttgggcg
      601 ctggcattaa cgcagtttgg tggcacgaaa tacacggcgc gaattgctaa agttggcttc
      661 ttcgccggta tcctgttacc tgcatttatt ttgatcgcat tagcggctat ttatctgcac
      721 tccggtgccc ccgttgctat cgaaatggat tcgaagacct tcttccctga cttctctaaa
      781 gtgggcaccc tggtagtatt tgttgccttc attttgagtt atatgggcgt agaagcatcc
      841 gcaacccacg tcaatgaaat gagcaaccca gggcgcgact atccgttggc tatgttactg
      901 ctgatggtgg cggcaatctg cttaagctct gttggtggtt tgtctattgc gatggtcatt
      961 ccgggtaatg aaatcaacct ctccgcaggg gtaatgcaaa cctttaccgt tctgatgtcc
     1021 catgtggcac cagaaattga gtggacggtt cgcgtgatct ccgcactgct gttgctgggt
     1081 gttctggcgg aaatcgcctc ctggattgtt ggtccttctc gcgggatgta tgtcacagcg
     1141 cagaaaaacc tgctgccagc ggcattcgct aaaatgaaca aaaatggcgt accggtaacg
     1201 ctggtcattt cgcagctggt gattacgtct atcgcgttga tcatcctcac caataccggt
     1261 ggcggtaaca acatgtcctt cctgatcgca ctggcgctga cggtggtgat ttatctgtgt
     1321 gcttatttca tgctgtttat tggctacatt gtgttggttc ttaaacatcc tgacttaaaa
     1381 cgcacattta atatccctgg tggtaaaggg gtgaaactgg tcgtggcaat tgtcggtctg
     1441 ctgacttcaa ttatggcgtt tattgtttcc ttcctgccgc cggataacat ccagggtgat
     1501 tctaccgata tgtatgttga attactggtt gttagtttcc tggtggtact tgccctgccc
     1561 tttattctct atgctgttca tgatcgtaaa ggcaaagcaa ataccggcgt cactctggag
     1621 ccaatcaaca gtcagaacgc accaaaaggt cacttcttcc tgcacccgcg tgcacgttca
     1681 ccacactata ttgtgatgaa tgacaagaaa cactaaccat gtctgaatgg ttataagaca
     1741 agggagcgat aattcatcgc tccctttttc gtgcttgctg tcgtattgac ttaacgggga
     1801 taagtacgag aatgagcgca catctgttta ccggaaacca gcacatatgg atatctgctc
     1861 ccgaaacaag aaattaacga ttagaagacc agcgatacta gttgcactgg cacttttact
     1921 gtgtagttgt aaaagcacgc ctccagagtc catggtgaca ccaccagcag gttcaaagcc
     1981 accagccacg acgcaacaat cgtcacaacc gatgcgtggc atctggctgg ccacggtttc
     2041 tcggctcgac tggccaccgg tttcctcggt taacattagt aaccccacca gccgggcccg
     2101 tgtacaacaa caggcgatga tcgacaaact ggatcatctg caacgtctcg gcataaacac
     2161 ggtctttttc caggtcaagc cggacggtac cgccctgtgg ccatcgaaaa ttttgccgtg
     2221 gtccgatctt atgaccggta agattggtga aaatccgggt tacgatccgc tgcaatttat
     2281 gctcgacgaa gcccacaagc gtgggatgaa agtacacgcc tggtttaacc cctatcgcgt
     2341 atcggttaat acgaagcccg gtactatcag ggaactgaat agcactctgt ctcaacaacc
     2401 ggcgagcgtc tatgtgcaac accgcgactg gatcagaacg tctggcgatc gctttgtcct
     2461 cgacccgggc atccctgagg ttcaggactg gatcacatca atagtcgcag aagtggtttc
     2521 ccgctatccc gtagatggcg tgcagtttga cgactatttc tatacggagt caccgggttc
     2581 acggctaaat gataacgaaa cgtaccgtaa atacggaggc gcatttgcgt caaaagcaga
     2641 ctggcggcgc aacaatactc agcagttaat tgcaaaggta tcgcacacca ttaaaagcat
     2701 taagccggga gtcgaatttg gtgttagccc ggcaggcgtg tggcgtaacc gatcacacga
     2761 tccgctcggt tccgataccc gaggcgcggc agcctatgac gaatcctacg ctgacacccg
     2821 tcgatgggtg gaacaaggat tgctggatta cattgctccc caaatttact ggccgttctc
     2881 acggagtgcc gcgcgttatg acgtgttggc aaaatggtgg gcggatgtcg ttaaaccgac
     2941 caggacccgc ctgtatatcg gtatcgcctt ctataaagtg ggtgaacctt caaagataga
     3001 gccagactgg atgattaacg gcggcgtacc ggaactgaaa aagcagctcg atcttaacga
     3061 tgctgtgccc gaaattagcg gcaccatctt gttccgtgag gactatctga ataaaccgca
     3121 gactcaacaa gcggtcagct atctgcaaag tcgctggggc agttaaactc ccattcttac
     3181 tttgtaacaa gccggtgctt tacccaccgg cttgttaccc tcttaaacta tcccactaat
     3241 aatcatgctt acttaagtca aattaaccac acttagttaa acagccataa atccctaata
     3301 aaaatgtatt aatatgaaaa accatacgat attcgctgtc accggaaaat aattacgatg
     3361 ggctatactc ttctgaagaa cagtagcgta gattgaaact gtcctaaatc gcttatttct
     3421 tttcagtata tcttcatatt tcaggagaat atggtgcagt tagtcgatct cgcacgttgc
     3481 gtttcatttt gattccgtct gatttcccag ccttataagg gtgtgaatta tggagatgta
     3541 ttttaaaaga atgaaagatg agtggaccgg acttgtcgaa caggcagatc cgcccattcg
     3601 tgctaaagcc gcggaaattg ccgttgcgca tgctcattat ctgagtatcg agttttatcg
     3661 aattgtccgc atcgacccgc atgccgaaga attcttgagt aatgaacaag ttgagcggca
     3721 gttgaagagt gcgatggaac gctggattat taacgtgctt tctgcccagg ttgacgatgt
     3781 cgaaaggcta atacaaatcc agcataccgt cgcggaagtg catgcccgca taggaattcc
     3841 ggtagaaatt gtcgagatgg ggtttcgggt gctgaaaaaa atcctctatc cggtgatctt
     3901 ctcttcggat tattccgccg cagaaaaact tcaggtctac catttctcga ttaacagtat
     3961 tgatatcgcg atggaagtga tgactcgcgc gtttaccttt agtgacagta gtgcctcaaa
     4021 ggaagatgaa aactatcgta tcttctcgtt actggaaaac gccgaagaag aaaaagaacg
     4081 gcaaatagcc tcaatacttt catgggaaat agatattatc tataaaatcc tgctggattc
     4141 tgatttaggc agtagtttgc ctttaagcca ggctgatttt ggcctgtggt ttaaccataa
     4201 aggtcgacat tattttagtg gtattgccga agtaggccat atctcccgtc tgattcagga
     4261 tttcgacggt attttcaatc aaaccatgcg taacaccaga aatttgaata acagaagtct
     4321 gcgggtgaaa tttttattac agataagaaa taccgtatcg caaattatta ccttgctgcg
     4381 tgaattgttt gaagaagtat cgcgccacga agtcggtatg gatgtactga cgaaattact
     4441 taaccgccgt ttcctaccga ctatcttcaa acgcgaaatt gcccatgcca accggaccgg
     4501 tacaccgctg tcagtgctga ttattgacgt tgataaattc aaagagatca acgatacgtg
     4561 gggccataac actggtgatg aaattctgcg taaagtctct caggcctttt atgacaacgt
     4621 ccgcagtagt gattatgttt tccgctacgg gggcgatgaa tttatcattg ttttgactga
     4681 agcttctgaa aacgaaacgt tacgtaccgc agaacgtatt cgcagtcggg tggagaaaac
     4741 caaactgaaa gccgcaaacg gcgaagatat tgccctctca ctttccatcg gtgccgccat
     4801 gtttaatggt catcctgact atgagcgcct cattcaaata gccgatgaag ctctgtatat
     4861 cgccaaaaga cgaggtagaa accgtgttga actctggaaa gccagtcttt agatgcgcca
     4921 ggatgcagag gtaatcatga agctaaccga tgcggataat gccgccgatg gcattttttt
     4981 ccccgccctt gagcaaaata tgatgggtgc ggtgttaatt aacgaaaatg atgaagtgat
     5041 gtttttcaac cccgccgcag agaagctctg gggatacaaa cgtgaagaag tcattggcaa
     5101 taacattgat atgctgattc cgcgggattt gcgtcctgcg catcctgaat acattcgtca
     5161 caaccgtgaa ggcggtaaag cgcgtgttga ggggatgagt cgggagctgc agctggagaa
     5221 aaaagacggc agtaaaatct ggacccgttt tgcgctatcg aaagtgagcg ccgaggggaa
     5281 agtttattac ctggcgctgg tacgggatgc cagcgtagaa atggcgcaaa aagaacagac
     5341 ccgacaattg attattgccg ttgaccatct cgaccgaccg gtgattgtcc tcgatccgga
     5401 acgccatatt gtgcagtgca atcgcgcatt taccgaaatg tttggttact gcattagcga
     5461 agccagcggt atgcagcccg atacactcct gaacattcct gaattccctg ccgataaccg
     5521 cattcgttta caacagttgc tatggaaaac cgcccgcgat caggacgaat ttctgctgtt
     5581 gacgcgcacc ggtgaaaaaa tctggattaa agcctctatc agcccggttt atgacgtgct
     5641 cgcgcatctg cagaacctgg taatgacttt ctcggatatc accgaagaac ggcagattcg
     5701 ccagcttgaa ggcaatattc tcgccgccat gtgcagcagc ccgccatttc atgaaatggg
     5761 ggaaatcatt tgtcgtaaca tcgaatctgt actcaacgaa tcgcatgttt cgctgttcgc
     5821 actgcgcaac gggatgccga tacactgggc gtcatcttcc cacggtgcag aaattcaaaa
     5881 tgcgcaaagc tggtcagcga ccattcgtca gcgtgatggc gcgcctgcgg ggatcctgca
     5941 aattaaaacc tcgtcaggag cagaaaccag cgcctttatc gaacgcgtgg cagatatcag
     6001 ccagcatatg gccgcgctgg cgctggaaca ggaaaaaagc cgtcagcata ttgaacaact
     6061 catccaattt gatccgatga ccggtctgcc aaatcgcaat aacctgcaca attacctcga
     6121 tgacctggtc gacaaagccg tctctcccgt ggtgtatctc atcggtgttg accatattca
     6181 ggatgtgatt gatagccttg gctatgcgtg ggccgatcag gcattgctgg aagtggtcaa
     6241 tcgctttcgt gaaaaactca aaccggatca gtatctctgt cgtatcgaag gtacgcagtt
     6301 tgtcctcgtg agcctcgaaa acgacgtcag taacattacc caaatcgccg atgagctacg
     6361 gaatgtggtc agcaagccga taatgattga cgataaaccc ttcccgctta ccttgagtat
     6421 tggcatcagc tacgacctgg gtaaaaaccg cgattacttg ctctccactg ctcacaatgc
     6481 aatggattat attcgcaaga atggcggtaa cggctggcag ttcttcagcc cggcgatgaa
     6541 cgaaatggta aaagagcgtt tggttttagg cgcagcgctg aaagaagcga ttagcaataa
     6601 ccaactgaaa ctggtttacc agccgcaaat cttcgcagaa acgggtgaac tgtacggcat
     6661 cgaagccctt gctcgctggc acgatcccct gcatggtcat gtgccccctt cacggtttat
     6721 tcctctcgca gaagagattg gtgaaatcga aaatattggg cgctgggtca tcgcggaagc
     6781 ttgccgtcag ttagcagaat ggcgtagcca gaatattcat atcccggcgt tatccgtgaa
     6841 cttgtcggcg ctgcactttc gcagtaatca actgtctaat caggtgtctg atgcaatgca
     6901 cgcctggggt attgacggcc accagctgac ggtagaaatc acggaaagca tgatgatgga
     6961 acacgatacc gaaatcttta agcgcattca gatcctgcgt gatatgggcg tgggcttatc
     7021 ggtagatgat tttggtacgg gcttttccgg attatcctgc ttagtcagtc ttccggtaac
     7081 ggaaatcaaa attgacaaaa gttttgtcga tcgttgtctg accgaaaaac gcatccttgc
     7141 cttacttgaa gccattacca gcattgggca aagcctcaat ttaaccgtcg tggcggaagg
     7201 cgtcgaaacc aaagagcaat ttgagatgct acgcaagatc cactgtcgcg ttattcaggg
     7261 atatttcttt tcccgccccc tacccgccga agaaattcca ggctggatga gcagcgtgtt
     7321 accgctgaaa atctgacaaa ttcctctcgc ccgcactcgc gggttttcat ttaacgtgac
     7381 actgtcactt aaatactgtg atttcagcta cgattccggg agattccttc cttaacttcc
     7441 cctcttgcac caaaactgca ctacgctgca caaatattga tcaaaagtta aaaaatataa
     7501 ctttaagcca gcattctggc gcttatcccg gcatggcatg agatctgcat aagcggaaag
     7561 cgcagcaatt tttgtcttat acaggaaccg tttatgtcgg ataccaccga actggttgat
     7621 ttagccgtaa tcttccctga tctggagatc gaattgaaat acgcctgcgc tgataacatc
     7681 acaggtaaag ctatttatca gcaagcgcgt tgtctgttac acaaggatgc gattaccgcg
     7741 ctggcgaaaa gtatcagcat cgcccagctg tcagggttac aactggtgat ttacgatgcg
     7801 tatcgcccac aacaagcaca ggcgatgttg tggcaagcct gcccagaccc gcaatatgtt
     7861 gttgatgtga cggtcggttc taatcacagc cgtggcacgg cgatcgacct gacgcttcgt
     7921 gatgagcacg ggaacatcct cgatatgggc gcagggttcg atgaaatgca cgagcgctcc
     7981 catgcctatc acccttccgt cccgcccgcc gctcagcgca atcggctgtt gctgaatgcg
     8041 ataatgactg gtggcggttt tgtcggtatc tccagcgaat ggtggcactt cgaattaccc
     8101 caggcagcga gttaccctct gctcgctgat caattctctt gttttatatc ccctggcaca
     8161 cagcacgtca gttaatcagg aaactgtcat gaagagatcg atatcgtttc gtcccacatt
     8221 gctcgcgctc gtccttgcca caaatttccc ggttgcgcac gccgccgtac caaaagatat
     8281 gctggtgatt ggtaaggccg ccgatccaca aaccctcgac ccggcggtaa caatagataa
     8341 taacgactgg acagtgacct acccgtctta tcagcggctg gttcagtaca aaacggacgg
     8401 tgataaaggc tcaaccgacg ttgaaggcga tctggcaagt agctggaaag cgtctgacga
     8461 tcaaaaagag tggacgttca ccctgaaaga taatgctaaa tttgccgatg gcacacctgt
     8521 cactgccgaa gcagtaaaac tttcttttga gcggctacta aaaatcggcc aggggccagc
     8581 agaagcattt cccaaagatt taaagattga tgctcccgac gaacatacgg tgaagtttac
     8641 ccttagccaa ccattcgcac cgttcctcta cacgctggcg aatgacggtg catccattat
     8701 caatccggcg gtcttaaagg aacatgcagc ggatgatgct cgcggcttcc tcgcgcaaaa
     8761 taccgccggt tccggaccat ttatgctgaa aagctggcaa aaaggtcagc aattagttct
     8821 ggtgccaaat ccgcattacc caggcaataa accgaacttc aaacgggtat cggtaaaaat
     8881 tattggtgaa agtgcctccc gtcgcctgca gctctcccgt ggcgacattg acattgccga
     8941 tgcgctgccg gtggatcaac tcaacgccct gaagcaggaa aataaagtca atgtggcaga
     9001 gtatccgtca ctgcgcgtta cctatctgta tctgaataac agcaaagcgc ctcttaatca
     9061 ggcggatctg cgtcgggcca tttcctggtc taccgattat cagggcatgg ttaacggcat
     9121 tctgagtggt aacggaaaac agatgcgcgg cccgattccg gaaggcatgt ggggctacga
     9181 tgcgacggca atgcaataca accatgacga aacgaaagcc aaagccgaat gggataaagt
     9241 gacgagcaaa cccaccagcc tgacgtttct ctactccgat aacgatccga actgggagcc
     9301 tattgctctg gcgacacaat ccagtctcaa caagctgggc atcattgtga agctggaaaa
     9361 gctggcgaac gccaccatgc gcgacagagt gggtaaaggt gattacgaca ttgcgattgg
     9421 caactggagt ccggattttg ccgacccgta tatgtttatg aattactggt ttgagtcaga
     9481 caaaaaaggt ctgccgggta accgctcgtt ctatgaaaac agtgaggtcg ataagttact
     9541 gcgcaatgcg cttgcgacca ccgaccagac gcagcgtacc cgggactacc agcaggcaca
     9601 gaaaatcgtc attgatgacg ctgcttatgt gtacctgttc cagaaaaact accaactggc
     9661 gatgaacaaa gaggtgaaag gctttgtgtt caatcccatg ctggaacagg tcttcaatat
     9721 caataccatg agtaaataac gtgaccttct ggagtatttt acgccaacgc tgctgggggc
     9781 tggtgctcgt ggtggcgggc gtctgcgtga ttacgtttat tatctcgcat ctgatccctg
     9841 gtgatccggc gcggttactg gcgggtgacc gcgccagcga tgctatcgtg gaaaatattc
     9901 gccagcaact gggactggac cagccactgt atgtacagtt ttaccgctac gtcagcgacc
     9961 tgtttcatgg tgacctggga acatccattc gtaccgggcg tccggtgctg gaagagttgc
    10021 gtatattttt cccggcgacg ctggagctgg cttttggtgc cctgctgctg gcactcctga
    10081 ttggcatccc gctgggcata ctctctgcag tctggcgaaa tcgctggctg gatcatctgg
    10141 tgcgaataat ggccattacc ggaatctcca cacctgcgtt ctggcttggg ctgggcgtca
    10201 ttgtgctgtt ttatggtcat ctgcaaattc ttcccggcgg cggaaggctt gatgactggc
    10261 tggatccacc aacgcacgtt accggctttt atctgctcga tgcgctgctt gaaggcaacg
    10321 gtgaagtctt cttcaatgcg ttgcaacatc tcatcttacc ggcattaacg ctggcgttcg
    10381 ttcacctggg aattgtcgct cgccagatcc gctcagcgat gctggaacaa ttgagtgaag
    10441 actacattcg taccgcccgg gccagcggct tgcccggctg gtatatcgtt ttatgttatg
    10501 cgctacccaa tgcgttgatc ccatcgatta ccgtattggg tttggcgctg ggcgatttgt
    10561 tgtatggcgc agtgctcacc gaaaccgttt ttgcctggcc cggaatgggt gcatgggtag
    10621 taacatcaat acaggcgctc gacttcccgg cagtgatggg ctttgccgtc gtggtttcat
    10681 ttgcttatgt gctggtcaac ctggtggtgg atttgctcta tttgtggatt gatccgcgta
    10741 tcggacgtgg aggtggtgaa tgatgctaag cgaggaaacg tccgccgtac gcccacaaaa
    10801 acaaacgcga tttaacggtg caaaactggt atggatgctg aaaggcagtc cgctcaccgt
    10861 gaccagcgca gtcatcattg tattaatgct attgatgatg attttttcac cgtggctggc
    10921 gacgcatgat cccaacgcca ttgatttaac cgcccgcctt ttgccgcctt ctgcggcgca
    10981 ctggtttggc accgatgaag tgggacgcga tctgtttagc cgcgtactgg tcggcagtca
    11041 gcaatcaatt ctcgccggat tagtcgtggt tgccattgcg ggtatgattg gttcgctact
    11101 cggatgtcta tccggtgtgc ttggtggacg cgcagacgcc atcatcatgc gcatcatgga
    11161 cattatgctg tcgattcctt cgttggtact gacaatggca ctggctgccg ctctcgggcc
    11221 gagtttgttt aacgccatgc tggctattgc tattgtgcga attccctttt atgtgcgcct
    11281 ggcgcggggg caagcattag ttgtacgcca gtatacctat gttcaggcgg cgaaaacctt
    11341 tggcgcgtct cgttggcatc tgatcaactg gcatatttta cgtaactccc taccgccgct
    11401 gatcgtgcag gcatcgctgg atatcggtag cgcgatttta atggccgcca cgttgggatt
    11461 tattggcctg ggtgctcaac aaccgagtgc tgaatggggc gcgatggtag caaatggtcg
    11521 caactatgta ctcgatcagt ggtggtattg cgcatttccg ggggcagcga ttttgcttac
    11581 cgccgtcggg tttaatctct ttggtgatgg tattcgcgat ctgcttgacc cgaaagcagg
    11641 aggaaagcag tcatgaccca acccgttctg gacattcaac aactgcattt gagtttcccc
    11701 ggttttaacg gtgatgttca cgcgctcaac aatgtgtcct tgcagattaa ccgcggtgaa
    11761 attgtcggtc tggtgggaga atccggctca ggtaaatcag tcaccgcaat gctgattatg
    11821 cgtctgctac cgacgggcag ttattgcgta catcgggggc agatttccct gctgggagaa
    11881 gatgttctta acgcgcggga aaaacagctt cgtcagtggc gcggcgcacg agtggcgatg
    11941 atctttcagg aaccgatgac cgccctcaat ccgacacgtc gaataggtct tcagatgatg
    12001 gacgtgatcc gccatcatca accaataagt cgtcgggaag ccagagctaa agcgattgac
    12061 ctgctggaag agatgcaaat cccggatgcc gtggaagtta tgtcgcgcta tccgtttgag
    12121 ctttcaggtg gtatgcgcca gcgggtaatg attgcgctgg cattctcctg cgagccgcaa
    12181 ttgattattg ccgacgaacc gactacggcg ctggacgtca cggtgcagtt gcaggtactg
    12241 cgtttgctta aacataaagc ccgcgccagt ggaactgcgg ttctgttcat cagccatgat
    12301 atggccgtgg tgtcgcaact gtgcgatagc gtttacgtga tgtatgccgg aagcgtaatt
    12361 gaaagcggcg tgacggcaga cgttatccat catccccggc atccgtatac cattggtttg
    12421 ctgcaatgcg caccagaaca tggagtacca cgccagctat tacccgccat tccagggacg
    12481 gtaccaaacc tcacccattt gcctgacggc tgcgcttttc gcgatcgttg ctatgcggca
    12541 ggtgcacagt gtgaaaacgt cccggcgctg acagcgtgtg gtgacaacaa ccagcgctgt
    12601 gcctgttggt atccgcagca ggaggttata agtgtctgac acgttattaa cgttacgcga
    12661 cgtccatatc aatttcccgg cccgtaaaaa ctggcttggt aaaactacgg aacatgttca
    12721 tgccattaat ggtattgatt tacagatccg ccgtggtgaa accttaggga tcgtcggcga
    12781 gtcaggctgc ggcaaaagca gcctcgcaca gcttttaatg ggtatgctgc aaccgagcca
    12841 cgggcagtac atccgttctg gctcacaacg cattatgcag atggtgtttc aggacccgct
    12901 ctcttcgctt aatccgcgct taccggtgtg gcgcatcatc acagaaccgc tctggatagc
    12961 taagcgtagt agtgaacaac agcggcgagc gttggcagag gagttggctg tgcaggtggg
    13021 tattcgtccg gagtatctcg accgcctgcc tcatgcgttc tccggcgggc agcggcaacg
    13081 tatcgccatt gccagagcac tctcttcgca gcctgacgtg attgtgcttg atgagccaac
    13141 ctctgcgctg gatatctccg ttcaggcgca gatcctcaat ttactggtaa cgctacagga
    13201 aaatcacggg ctgacctatg tgctgatttc acacaatgtc tcggtgatac gtcatatgag
    13261 cgatcgggtg gcggtgatgt atctcgggca gattgtagaa ctgggcgacg cgcagcaggt
    13321 gctgacggca cctgcacatc catacacccg attattgctg gattccctcc ccgccattga
    13381 taaaccgctg gaggaagaat gggcattacg taaaacggat ctgccgggaa accgcacgtt
    13441 gccgcaaggc tgttttttct acgaacgttg cccgctggca acccacggat gtgaagtccg
    13501 gcaatcatta gcaataaggg aggacggacg tgagctccgg tgctggcggg cgctgtagag
    13561 atgctaacgc tgtagagatg ctaacaacgc atcaggcatt cacgcgcctg acgcgtcatc
    13621 cggcaatgct ttacgatttc aactggtaat ccagcgtaat ttccgctttc agtacctgag
    13681 agaccgggca tcctgctttt gctttctgga ttatgccgtc aaaggtagag gcatcaatac
    13741 ccggcaccgc aacttcactc ttcagtgcga ttttcgtaat cgcaaaaccg gcatccactt
    13801 tatccagcga cacatcggcg gtggtatcaa tcgatgttgg cgtgaatccc gcttccccca
    13861 gcattaatga aagcgccatt gagaaacatg cggcatgcgc tgcgccaatc agttcttcag
    13921 ggttggttcc tttttcgcct tcaaaacgcg tgttaaatcc atacggctgt tggttcagca
    13981 cgccactctc ggtggatact gttcccttcc cgcgtttgat atcgccttcc cagtgtgcct
    14041 gacctttctt atggattgtc attgttgctc tcctgtgggc ttaaaaagga aattatagac
    14101 tacgtgagaa acagcacgag gataagcagg atattccgaa taaaatccgg cgaaaatatt
    14161 acttctgcac ttaaattaaa ttcccacaat agattaccgg gaatatataa cccaaaagat
    14221 attgtatcaa tattaatcgg atcataccaa tcacaatccc tatgaatatc atggtgttaa
    14281 aatataaaaa tcatcaacca ggactaatct taacaacgaa gcggcaaata tttgccatgc
    14341 tgaatgtgct ttataaatct gcgatccgta gcagacacca taaatacaca gacacggaga
    14401 atcactatgt ttacttatta tcaggcagaa aattcaacag cagaacccgc tctggttaat
    14461 gccattgagc aaggccttcg ggcacagcat ggtgttgtca ctgaagatga cattctcatg
    14521 gagctgacca aatgggttga agcttctgat aacgacatcc tcagtgatat ctaccagcaa
    14581 acgatcaatt atgtggtcag tggccagcac cctacgcttt aaggtgctat gcttgatcgg
    14641 caacctaatt taggggttta gcacgtgttt cttcgctacg gcgatgttgt ccttaaaact
    14701 agctacagga ttgaggagtt aaaatgaaat cgaaccgtca ggcacgtcat attcttggac
    14761 tggaccataa aatttctaac cagcgcaaaa tagttaccga aggtgacaaa tccagcgtag
    14821 taaataaccc aaccggcaga aaacgccccg ctgaaaagta attcataacc atcagtcctc
    14881 aatgacgatt aaacaccatt gcctgcgcaa tggtgttttt gtttttatct gctttatact
    14941 tgaggccgac gccctggcgg taaagcaaag acgataaaag ccccccaggg atggatattc
    15001 aaaaaagagt gagtgacatg gaaccaaaaa caaaaaaaca gcgttcgctt tatatccctt
    15061 acgctggccc tgtactgctg gaatttccgt tgttgaataa aggcagtgcc ttcagcatgg
    15121 aagaacgccg taacttcaac ctgctggggt tactgccgga agtggtcgaa accatcgaag
    15181 aacaagcgga acgagcatgg atccagtatc agggattcaa aaccgaaatc gacaaacaca
    15241 tctacctgcg taacatccag gacactaacg aaaccctctt ctaccgtctg gtaaacaatc
    15301 atcttgatga gatgatgcct gttatttata ccccaaccgt cggcgcagcc tgtgagcgtt
    15361 tttctgagat ctaccgccgt tcacgcggcg tgtttatctc ttaccagaac cggcacaata
    15421 tggacgatat tctgcaaaac gtgccgaacc ataatattaa agtgattgtg gtgactgacg
    15481 gtgaacgcat tctggggctt ggtgaccagg gcatcggcgg gatgggcatt ccgatcggta
    15541 aactgtcgct ctataccgcc tgtggcggca tcagcccggc gtataccctt ccggtggtgc
    15601 tggatgtcgg aacgaacaac caacagctgc ttaacgatcc gctgtatatg ggctggcgta
    15661 atccgcgtat cactgacgac gaatactatg aattcgttga tgaatttatc caggctgtga
    15721 aacaacgctg gccagacgtg ctgttgcagt ttgaagactt tgctcaaaaa aatgcgatgc
    15781 cgttacttaa ccgctatcgc aatgaaattt gttcttttaa cgatgacatt cagggcactg
    15841 cggcggtaac agtcggcaca ctgatcgcag caagccgcgc ggcaggtggt cagttaagcg
    15901 agaaaaaaat cgtcttcctt ggcgcaggtt cagcgggatg cggcattgcc gaaatgatca
    15961 tctcccagac ccagcgcgaa ggattaagcg aggaagcggc gcggcagaaa gtctttatgg
    16021 tcgatcgctt tggcttgctg actgacaaga tgccgaacct gctgcctttc cagaccaaac
    16081 tggtgcagaa gcgcgaaaac ctcagtgact gggataccga cagcgatgtg ctgtcactgc
    16141 tggatgtggt gcgcaatgta aaaccagata ttctgattgg cgtctcagga cagaccgggc
    16201 tgtttacgga agagatcatc cgtgagatgc ataaacactg tccgcgtccg atcgtgatgc
    16261 cgctgtctaa cccgacgtca cgcgtggaag ccacaccgca ggacattatc gcctggaccg
    16321 aaggtaacgc gctggtcgcc acgggcagcc cgtttaatcc agtggtatgg aaagataaaa
    16381 tctaccctat cgcccagtgt aacaacgcct ttattttccc gggcatcggc ctgggtgtta
    16441 ttgcttccgg cgcgtcacgt atcaccgatg agatgctgat gtcggcaagt gaaacgctgg
    16501 cgcagtattc accattggtg ctgaacggcg aaggtatggt actgccggaa ctgaaagata
    16561 ttcagaaagt ctcccgcgca attgcgtttg cggttggcaa aatggcgcag cagcaaggcg
    16621 tggcggtgaa aacctctgcc gaagccctgc aacaggccat tgacgataat ttctggcaag
    16681 ccgaataccg cgactaccgc cgtacctcca tctaagcctg cgcccggtag tgaaggctac
    16741 cgggctattt ccctctccct ttttcagatc tcatccatac tgggtagtgg cgaataaatc
    16801 tcatttgcct cacctgctat gcagaacatc atccgaaaag gaggaactat gaaggctgca
    16861 gttgttacga aggatcatca tgttgacgtt acgtataaaa cactgcgctc actgaaacat
    16921 ggcgaagccc tgctgaaaat ggagtgttgt ggtgtatgtc ataccgatct tcatgttaag
    16981 aatggcgatt ttggtgacaa aaccggcgta attctgggcc atgaaggcat cggtgtggtg
    17041 gcagaagtgg gtccaggtgt cacctcatta aaaccaggcg atcgtgccag cgtggcgtgg
    17101 ttctacgaag gatgcggtca ttgcgaatac tgtaacagtg gtaacgaaac gctctgccgt
    17161 tcagttaaaa atgccggata cagcgttgat ggcgggatgg cggaagagtg catcgtggtc
    17221 gccgattacg cggtaaaagt gccagatggt ctggactcgg cggcggccag cagcattacc
    17281 tgtgcgggag tcaccaccta caaagccgtt aagctgtcaa aaattcgtcc agggcagtgg
    17341 attgctatct acggtcttgg cggtctgggt aacctcgccc tgcaatacgc gaagaatgtc
    17401 tttaacgcca aagtgatcgc cattgatgtc aatgatgagc agttaaaact ggcaaccgaa
    17461 atgggcgcag atttagcgat taactcacac accgaagacg ccgccaaaat tgtgcaggag
    17521 aaaactggtg gcgctcacgc tgcggtggta acagcggtag ctaaagctgc gtttaactcg
    17581 gcagttgatg ctgtccgtgc aggcggtcgt gttgtggctg tcggtctacc gccggagtct
    17641 atgagcctgg atatcccacg tcttgtgctg gatggtattg aagtggtcgg ttcgctggtc
    17701 ggcacgcgcc aggatttaac tgaagccttc cagtttgccg ccgaaggtaa agtggtgccg
    17761 aaagtcgccc tgcgtccgtt agcggacatc aacaccatct ttactgagat ggaagaaggc
    17821 aaaatccgtg gccgcatggt gattgatttc cgtcactaag aggcctttgc tgcgactgcc
    17881 atgttcgggt cgcagcatcg cacactctcc aacatgaaat ggctaaatgg attattgttg
    17941 cgtaggaagg aacaataatg atagtgttcc cagtgaagga acgctactga gagtaaagac
    18001 actaatgaaa atggccaatc atccccgccc gggggacatt attcaggaat cactggacga
    18061 acttaatgtc agcctgcgcg agtttgccag agcaatggaa attgctccct caacggcaag
    18121 ccgattgctg acaggaaaag cagctttgac gccagaaatg gcgattaaac tttccgtggt
    18181 gatcggcagt tcgccgcaaa tgtggctgaa tctgcaaaac gcctggagtc tggcagaggc
    18241 agaaaaaaca gtggatgtgt cgcgattacg ccgtctggtt acgcaataaa aaaatggcac
    18301 tttataaagc gccatttaga actgatgaca aacgcaacat tgcctgatgc gctacgctta
    18361 tcaggcctac acgttcactg caatctattg gatttgaagg gttttcatgc cggatgcggc
    18421 gtgaacgcct tatccggcat gaacaaagcc tacgttgtct acaatatgaa aatggcgcct
    18481 tttacagcgc cattttcagc ttaaagttca aaagagatta tatcccttct tcactctctt
    18541 ttttcgcttc tgccttctcg atttcacgat accagcgcgg atggtgtttc ttcgcccagc
    18601 gacgacttac cttcccttcg atcatccctt taatcgatcc tttcacccaa aatgccatat
    18661 acatatggat caggatggcg tggatcagga tgatacccgc agccgcgtgg atcagcaggc
    18721 tgtagcgaac aacctgcatc gggaagtact gcgcaaagta cggacgccag ataatcaccc
    18781 cggtcaccag cagcacgaaa atcatgctca tgatcgacca gaacatcatc ttttgcccgg
    18841 cgttgtactt accgacatcc gccactttat gctcattgcc tttcaatact tcgacaatgt
    18901 tcaacagcca cggaatatct ttcttatccg ggatgttgtg atgcacaaaa cgcacaaaca
    18961 taaacatcag tgcgacgaaa atcgcaatgc cgaagaacgg gtgcaaaatg cgtcccatct
    19021 gcggcgtacc gaaggtttgc gtcagccatt gcagcgtcgg gaagaagaac gaaatcccgg
    19081 acagcgccac caggaagaag caaatcacca cggtccagtg acaggcgcga tcaataaatt
    19141 tggtgcgcac aatcattttc gacttactca tgatgatcct cctcgtcatc gtccacttcc
    19201 ttattcgggc caataccgat gtagtggaaa atcaacccgg caaaagtggc aataaagcca
    19261 gccgctgcca gcggtttcaa cgcgcctttc cacaggctta ccgaggtgtc gatcttcgga
    19321 tctttcggca gaccgtgata cagctccggc tgatcggcgt gatgcagcac gtacataacg
    19381 tgcgtaccac cgaccccttc cgggttgtag acgccagcat gttcgtaacc acgcgctttc
    19441 agtttcgcca cgcgctgttc cgccagctcc agcatctcct tcttggtgcc gaagtggata
    19501 gccccggtcg gacaggtttt cacacaagcc ggttcctggc cgacgctgac gcgatcgacg
    19561 cagagcgtgc atttatatac ccggttatcc tctttgttga ggcgcggaat attaaacgga
    19621 cacccggcaa tgcagtaacc acagccgatg cagttttccg actggaaatc gacaatcccg
    19681 ttagcgtact gaatgattgc accagcagac gggcacgcct tcaggcagcc gggatcttca
    19741 cagtgcatac agccgtcttt acggatcagc cactccagct tgccgttctg ttcggtttcg
    19801 ctaaagcgca tcaccgtcca ggacttggcg ctcagatcgg cggggttatc gtaaaccccg
    19861 acgcagtgcc ccacttcatc acggatgtcg ttccactccg aacacgccac ctgacaggct
    19921 ttacagccga tacaggtgga aacgtcgata agttttgcga cttctgcttt gtaatcacgc
    19981 acctgagaag gcggcgtgat ggagttagtt gcggaccttt tgataatgtc ctgcgtttcc
    20041 atagccatct gttcgccccc ttacgccttc tcgatgttga ctaagaacgc tttatattcc
    20101 ggcgtttgcg agtttgcatc accgacattc ggcgtcagag tgttagcgat ataaccttta
    20161 cgcgcgacac cctcaaagcc ccagtggatt ggaataccca ccgtttcaac ctgctgacca
    20221 tttacattca gcggtttcag acgacgcgtt accacagcca ccgcgcggat aaagccacgc
    20281 ttgctggaga cagtgacacg atcgccatta ttaatgcctt tcgccgccgc cagcgtttcg
    20341 ctgatttcca caaactgttc cggctgagca attgcgttga gcaatgcgtg cttggtccag
    20401 gtgtggaagt gctcggtcag acgataggtc gtacccacat acgggaactg ctctttttta
    20461 cccatccgca gcgcgtcttg ttcatacaga cgaacaaccg ggttagacac cacgttcgga
    20521 tgcagcgggt tagtgcccag cggcgtttca atcggctcgt agtgttccgg gaacggacct
    20581 tccgccattt tgttgatggc aaacaggcgt cccatccctt ccggctgcat gataaacggc
    20641 ccggttggcg tacccggtgc ggcattgccg aagtcaggaa tatcgttacc cgtccacttg
    20701 ctgccgttcc actggatcag catccgtttc ggatcccacg gtttaccgtt gatatccgcc
    20761 gaagcacggt tgtacagcac gcgacggttg agcggccacg cccaggccca tcccagcgta
    20821 ttccccagac cggacgggtc ggagttatcg cggttagcca tctggttgcc ctgctctgtc
    20881 cagctaccgg tgtagatcca gcaagaagat gcggttgtac cgtcatcacg cagatgcgca
    20941 aagctactca gcaactgacc tttcttcgca ataagcacgc cattagcgtc atagagatct
    21001 tccagcgcgt agccgttgtt ctctttagcc acttcgtcag attgcggttc gtgcggctgc
    21061 ttgtagttcc agctcatctt catcagcggt tctacgcctt taccaccttc ggactggtac
    21121 agctcgcgca gatgatggta gatacccgcc agaatttcac cgtcgttacg cgcttcgccc
    21181 ggcgcgtcct gacctttcca gtgccactgc aaccagcgac cggagttagc gatagaacca
    21241 tcttcttcag caaagcaggt cgaaggcaga cggaatactt cagtctgaat agacgccgga
    21301 tcgacatcgt tcgactcacc gtggttctgc cagaaggtag aggtttcagt caccagcgga
    21361 tcgataacca ccatgtactt cagcttgctc aggcagctca ccactttgtt tttgtccggg
    21421 aaggacgcaa ccgggttaaa gccctggcag aaataaccgg tgactttgcc ttcatccatc
    21481 atgttgaaat acttgatgac gtcgtaggtc tggtcccact tcggcagcca gtcatagccc
    21541 cagttgttct ctttctgcgc ggcatcgcca tagaaagatt tcatcaggct aacgaagaac
    21601 ttcggatagt tgctccagta gttcacctga tcagccagcg tcgctttcgg cgtgttcgct
    21661 tccagatacg actgcaaatc aacctgtttt tctgacggca gcgtcagata acctggcagg
    21721 ctggtagaga gcaggcctaa gtcagtcaag ccctgaatgt tggagtgacc acgcaatgcg
    21781 ttcacgccgc caccggccat acccatgtta ccgagcagca actggatcat cgccatagta
    21841 cggatgttct gcgcacccac agtgtgctgc gtccagccca gcgcgtacag gaaggtggtt
    21901 gtgcgatccg gtgcgctggt ggaggccagc acttcacaca ctttcaggaa gtcggctttt
    21961 ggcgtaccgc agatgttttc aacgacgtcc ggcgtgtagc gggaaacgtg ctctttcagc
    22021 aggttccaca cacagcgcgg atgagtcagt gtttcatcgc gtttcgcata gccgttttca
    22081 tcgaactgat agttccagga cgatttatcg tattgacgtt tttcagcgtc gtagccgctg
    22141 aacagaccgt cttcgaaagc aaaatcatca cgcaccagca ggctggcgtt ggtgtaatgc
    22201 ttaacgtatt cggcgttgat tttgttgttt tcgatcaggt agcgcaaaac gccagacagg
    22261 aacgtaatgt ccgtaccgga acgaataggc gcgtaaatat ccgccacaga agcggtacgc
    22321 gtaaaacggg gatcgacaac gatcaaggtt gcgtcgttgt tgtttttcgc ttccatcgcc
    22381 cagcggaaac cgacgggatg cgcttcagca gcgttaccgc ccatcaccat cacgacgtta
    22441 gcgtttttga tatccaccca gtggttggtc atcgcaccgc gaccaaatgt tggagcaaga
    22501 cttgctaccg ttggtccgtg tcagacgcgc gcctggttgt ctaccgccag catcccgagg
    22561 gagcgggcaa atttctgggt cagcatcccg gtttcgttgc tggcaccgga ggcacacagc
    22621 ataccggtag aaagccaacg gtttaccgtt acgccctgct cgttcttttc aataaagtta
    22681 gcgtcacggt cagctttcat cagcttcgca atacgggaga atgcttcttc ccagctaatg
    22741 cgctgccatt tgtcagaacc tggcgcacga tattccgggt agcgcagacg gttttcactg
    22801 ttgacgtaat ccagcaaacc ggcccctttc gggcacagcg caccacggct taccggatga
    22861 tccgggtcac cttcaatgtg ataaatcgct tctctggcgt tttttgcgcc atcacccagg
    22921 ctatacatca atagcccgca acctacggaa cagtatgtgc aggtgttacg gatctcttta
    22981 gcgcgtaata atttgtagtt tcgcgcctga gccagtgctt gcttcggggc aaagcccaat
    23041 gccgctactg ttgttccagc cataccgccc gcgcagattt taaaaaattg tctgcgactg
    23101 acgtccattg ctttcctctt ttttcagggg tattactgcg cgaggaaact aacagtaaaa
    23161 ttctgaatct ttttgcgcga aatcaaaaag aacatctgtt tgccacaaaa taatccgcct
    23221 tcgcaaattg acctacctca atagcggtag aaaaacgcac cactgcctga caggccagtt
    23281 aaaaaaatgc tataaaattc agcttaattt ttaacggcaa gagagacaaa acagcgagca
    23341 tgacacgaca aaaagcaacg ctcatagggc tgatagcgat cgtcctgtgg agcacgatgg
    23401 taggattgat tcgcggtgtc agtgaggggc tcggcccggt cggcggcgca gctgctatct
    23461 attcattaag cgggctgctg ttaatcttca cggttggatt tccgcgtatt cggcaaatcc
    23521 cgaaaggcta tttactcgcc gggagtctgt tattcgtcag ctatgaaatc tgtctggcgc
    23581 tttccttagg gtatgcggcg acccatcatc aggcgattga agtgggtatg gtgaactatc
    23641 tgtggcccag cctgacaatt ctctttgcca ttctgtttaa tggtcagaaa accaactggt
    23701 tgattgtacc tggattatta ttagccctcg tcggcgtctg ttgggtgtta ggcggtgaca
    23761 atgggttaca ttatgatgaa atcatcaata atatcaccac cagcccattg agttatttcc
    23821 tggcgttcat tggtgcgttt atctgggcag cctattgcac agtaacgaat aaatacgcac
    23881 gcggatttaa tggaattacc gtttttgtcc tgctaacggg agcaagtctg tgggtttact
    23941 attttcttac gccacaacca gaaatgatat ttagcacgcc cgtcatgatt aaactcatct
    24001 ctgcggcatt taccttagga tttgcttatg ctgcatggaa tgtcggtata ttgcatggca
    24061 atgtcaccat tatggcggta ggttcgtatt ttacgcctgt actttcctca gcgcttgcag
    24121 ccgtgctgct cagcgccccg ctgtcgttct cgttctggca aggcgcgctg atggtctgcg
    24181 gcggttccct gctctgctgg ctggcgacac gtcgtggtta aaataactgc cgggtc
//
LOCUS       DACAOP010000067        24198 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.067, whole genome shotgun sequence.
ACCESSION   DACAOP010000067 DACAOP010000000
VERSION     DACAOP010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24198
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.067"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(73..2142)
                     /gene="glyS"
                     /locus_tag="IT892_002962"
     CDS             complement(73..2142)
                     /gene="glyS"
                     /locus_tag="IT892_002962"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAP3136154.1"
                     /translation="MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGT
                     VQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITV
                     DQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
                     VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIAD
                     YEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEA
                     LVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFF
                     NTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLL
                     SKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVAC
                     ALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAV
                     RLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKA
                     VSHFRTLDAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDK
                     LEPYFTEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRV
                     ADISLLQ"
     gene            complement(2152..3063)
                     /gene="glyQ"
                     /locus_tag="IT892_002963"
     CDS             complement(2152..3063)
                     /gene="glyQ"
                     /locus_tag="IT892_002963"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAP3136155.1"
                     /translation="MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMT
                     CLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSL
                     KELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVT
                     GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDF
                     LFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRI
                     RTLTKAVAEAYYASREALGFPMCNKDK"
     gene            complement(3158..3457)
                     /locus_tag="IT892_002964"
     CDS             complement(3158..3457)
                     /locus_tag="IT892_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136156.1"
                     /translation="MMMNAFFPAMALMVLVGCSIPSPVQKAQRVKVDPLRSLNMEALC
                     KDQAAKRYNTGEQKIDVTAFEQFQGSYEMRGYTFRKEQFVCSFDADGHFLHLSMR"
     gene            3631..4626
                     /locus_tag="IT892_002965"
     CDS             3631..4626
                     /locus_tag="IT892_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAP3136157.1"
                     /translation="MQPKIYWIDNLRGIACLMVVMIHTTTWYVTNAHSVSPVTWDIAN
                     VLNSASRVSVPLFFMISGYLFFGERSAQPRHFLRIGLCLIFYSAIALLYIALFTSINM
                     ELALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMAVIGIIANPNTV
                     PQKIDGFEWLPINLYINGDTFYYILYGMLGRAIGMMDTQHKALSWVSAALFATGVFII
                     SRGTLYELQWRGNFADTWYLYCGPMVFICAIALLTLVKNTLDTRTIRGLGLISRHSLG
                     IYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAASLLLSMLVQRIDRNRLVS"
     gene            complement(4668..5105)
                     /locus_tag="IT892_002966"
     CDS             complement(4668..5105)
                     /locus_tag="IT892_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiaB family inner membrane protein"
                     /protein_id="HAP3136158.1"
                     /translation="MDNKISTYSPAFSIVSWIALVGGIVTYLLGLWNAEMQLNEKGYY
                     FAVLVLGLFSAASYQKTVRDKYEGIPTTSIYYMTCLTVFIISVALLMVGLWNATLLLS
                     EKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKETQVTQEEYSE"
     gene            complement(5151..5492)
                     /locus_tag="IT892_002967"
     CDS             complement(5151..5492)
                     /locus_tag="IT892_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136159.1"
                     /translation="MKTSKTVAKLLFVVGALVYLVGLWISCPLLSGKGYFLGVLMTAT
                     FGNYAYLRAEKLGQLDDFFTHICQLVALITIGLLFIGVLNAPINTYEMVIYPIAFFVC
                     LFGQMRLFRSA"
     gene            complement(5661..7115)
                     /gene="xylB"
                     /locus_tag="IT892_002968"
     CDS             complement(5661..7115)
                     /gene="xylB"
                     /locus_tag="IT892_002968"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HAP3136160.1"
                     /translation="MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQD
                     PEQWWQATDRAMKALGDQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCA
                     QECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
                     TGEFASDMSDAAGTMWLDVAKRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAK
                     AWGMATVPVVAGGGDNAAGAVGVGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHS
                     FCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALIAAAQQADESAEPVWFLPYLS
                     GERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTL
                     IGGGARSEYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLP
                     LEQSHLPDAQRYAAYQPRRETFRRLYQQLLPLMA"
     gene            complement(7187..8509)
                     /gene="xylA"
                     /locus_tag="IT892_002969"
     CDS             complement(7187..8509)
                     /gene="xylA"
                     /locus_tag="IT892_002969"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HAP3136161.1"
                     /translation="MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRF
                     AACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHD
                     VDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
                     EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVE
                     HKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAG
                     HSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTG
                     GLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNS
                     ELGQQILKGQMSLADLAKYAQEHHLSPVHQSGRQEQLENLVNHYLFDK"
     gene            8875..9867
                     /locus_tag="IT892_002970"
     CDS             8875..9867
                     /locus_tag="IT892_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose-binding periplasmic protein"
                     /protein_id="HAP3136162.1"
                     /translation="MKIKNILLTLCTSLLLTNVAAHAKEVKIGMAIDDLRLERWQKDR
                     DIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEA
                     KQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNN
                     AKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVAS
                     NDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAE
                     IAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDGFHKESEL"
     gene            9945..11486
                     /gene="xylG"
                     /locus_tag="IT892_002971"
     CDS             9945..11486
                     /gene="xylG"
                     /locus_tag="IT892_002971"
                     /EC_number="7.5.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter ATP-binding protein"
                     /protein_id="HAP3136163.1"
                     /translation="MPYLLEMKNITKTFGSVKAIDNVCLRLNAGEIVSLCGENGSGKS
                     TLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENI
                     FLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQ
                     VRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDG
                     QHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKR
                     VNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQA
                     IAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQL
                     KVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQ
                     LVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHV
                     EKQSV"
     gene            11464..12645
                     /gene="xylH"
                     /locus_tag="IT892_002972"
     CDS             11464..12645
                     /gene="xylH"
                     /locus_tag="IT892_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose ABC transporter permease XylH"
                     /protein_id="HAP3136164.1"
                     /translation="MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFT
                     WTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGVAAICD
                     VWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
                     TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVV
                     GRQALTAIIVLGAIWLLNDYRGVPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLE
                     AARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGNIAELDAIAACVIGG
                     TSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRR
                     S"
     gene            12723..13901
                     /locus_tag="IT892_002973"
     CDS             12723..13901
                     /locus_tag="IT892_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XylR family transcriptional regulator"
                     /protein_id="HAP3136165.1"
                     /translation="MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEED
                     FRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATD
                     NYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
                     ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGI
                     DNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRS
                     TDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMI
                     HAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
                     "
     gene            complement(14097..14921)
                     /locus_tag="IT892_002974"
     CDS             complement(14097..14921)
                     /locus_tag="IT892_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein bax"
                     /protein_id="HAP3136166.1"
                     /translation="MILTPIRRYGAMILMLLTLVFSSEVLAKTHTTTASQKSHLTKAS
                     NKQVSSKQEYSRNSAKSSSLPDLRKYPSGTPRKKAFLRTVMPYITSQNAAITAERNWL
                     ISKQYQGQWSPAERARLKDIAKRYKVKWSGNTRKIPWNTLLERVDIIPTSMVATMAAA
                     ESGWGTSKLARNNNNLFGMKCMKGRCTNAPGKVKGYSQFSSVKESVSAYVTNLNTHPA
                     YSSFRKSRAQLRKADQEVTATAMIHKLKGYSTKGKSYNNYLFAMYQDNQRLIAAHM"
     gene            15241..17271
                     /gene="malS"
                     /locus_tag="IT892_002975"
     CDS             15241..17271
                     /gene="malS"
                     /locus_tag="IT892_002975"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HAP3136167.1"
                     /translation="MKLAACFLTLLPGFAVAASWTSPGFPAFSEQGTGTFVSHAQLPK
                     GTRPLTLNFDQQCWQPADAIKLNQMLSLQPCSNTPPQWRLFRDGEYTLQIDTRSGTPT
                     LMISIQNAAEPVASLVRECPKWDGLPLTVDVSATFPEGAAVRDYYSQQIAIVKNGQIM
                     LQPAATSNGLLLLERAETDTSAPFDWHNATVYFVLTDRFENGDPSNDQSYGRHKDGMA
                     EIGTFHGGDLRGLTNKLDYLQQLGVNALWISAPFEQIHGWVGGGTKGDFPHYAYHGYY
                     TQDWTNLDANMGNEADLRTLVDSAHQRGIRILFDVVMNHTGYATLADMQEYQFGALYL
                     SGNEVKKSLGERWSDWKPAAGQTWHSFNDYINFSDKTGWDKWWGKNWIRTDIGDYDNP
                     GFDDLTMSLAFLPDIKTESTTASGLPVFYKNKMDTHAKAIDGYTPRDYLTHWLSQWVR
                     DYGIDGFRVDTAKHVELPAWQQLKTEASAALREWKKANPDKALDDKPFWMTGEAWGHG
                     VMQSDYYRHGFDAMINFDYQEQAAKAVDCLAQMDTTWQQMAEKLQGFNVLSYLSSHDT
                     RLFREGGDKAAELLLLAPGAVQIFYGDESSRPFGPTGSDPLQGTRSDMNWQDVSGKSA
                     ASVAHWQKISQFRARHPAIGAGKQTTLLLKQGYGFVREHGDDKVLVVWAGQQ"
     gene            17449..18702
                     /gene="avtA"
                     /locus_tag="IT892_002976"
     CDS             17449..18702
                     /gene="avtA"
                     /locus_tag="IT892_002976"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HAP3136168.1"
                     /translation="MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIP
                     EMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIAL
                     TNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
                     PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVID
                     NAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGI
                     ISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPENRCLIHK
                     PEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYV
                     PEPEKIEAGVKILAEEIERAWAESH"
     gene            complement(18853..19326)
                     /locus_tag="IT892_002977"
     CDS             complement(18853..19326)
                     /locus_tag="IT892_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAP3136169.1"
                     /translation="MNRFIIADATKCIGCRTCEVACAVSHHENQDCAALSPDEFISRI
                     RVIKDHCWTTAVACHQCEDAPCANVCPVDAISREHGHIFVEQTRCIGCKSCMLACPFG
                     AMEVVSSRKKARAIKCDLCWHRETGPACVEACPTKALQCMDVEKVQRHRLRQQPV"
     gene            complement(19428..20276)
                     /gene="yiaJ"
                     /locus_tag="IT892_002978"
     CDS             complement(19428..20276)
                     /gene="yiaJ"
                     /locus_tag="IT892_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator YiaJ"
                     /protein_id="HAP3136170.1"
                     /translation="MGKEVMGKKENEMAQEKERPAGSQSLFRGLMLIEILSNYPNGCP
                     LAHLSELAGLNKSTVHRLLQGLQSCGYVTTAPAAGSYRLTTKFIAVGQKALSSLNIIH
                     IAAPHLEALNIATGETINFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMG
                     KIYMAFGHPDYVKSYWESHQHEIQPLTRNTITELPAMFDELAHIRESGAAMDREENEL
                     GVSCIAVPVFDIHGRVPYAVSISLSTSRLKQVGEKNLLKPLRETAQAISNELGFTVRD
                     DLGAIT"
     gene            20477..21475
                     /gene="yiaK"
                     /locus_tag="IT892_002979"
     CDS             20477..21475
                     /gene="yiaK"
                     /locus_tag="IT892_002979"
                     /EC_number="1.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydro-L-gulonate 2-dehydrogenase"
                     /protein_id="HAP3136171.1"
                     /translation="MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSH
                     GVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAA
                     DHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLI
                     VAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRI
                     LPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPT
                     RDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL"
     gene            21487..21954
                     /locus_tag="IT892_002980"
     CDS             21487..21954
                     /locus_tag="IT892_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF386 domain-containing protein"
                     /protein_id="HAP3136172.1"
                     /translation="MIFGHIAQPNPCRLPAAIEKALDFLRATDFNALEPGVVEIDGKN
                     IYTQIIDLTTREAVVNRPEVHRRYIDIQFLAWGEEKIGIAIDTGNNKVSESLLEQRNI
                     IFYHDSEHESFIEMIPGSYAIFFPQDVHRPGCIMQTASEIRKIVVKVALTALN"
     gene            22072..22545
                     /gene="yiaM"
                     /locus_tag="IT892_002981"
     CDS             22072..22545
                     /gene="yiaM"
                     /locus_tag="IT892_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter small
                     permease YiaM"
                     /protein_id="HAP3136173.1"
                     /translation="MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYL
                     FVWLTFIGAIVAFMDNAHVQVTFLVEKLSPAWQRRVALVTHSLILFICGALAWGATLK
                     TIQDWSDYSPILGLPIGLMYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA"
     gene            22548..23825
                     /gene="yiaN"
                     /locus_tag="IT892_002982"
     CDS             22548..23825
                     /gene="yiaN"
                     /locus_tag="IT892_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter large permease
                     YiaN"
                     /protein_id="HAP3136174.1"
                     /translation="MAVLIFLGCLLGGIAIGLPIAWALLLCGAALMFWLDMFDVQIMA
                     QTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVLAAM
                     IMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFG
                     VSSGLSISKLFMAGIAPGMMMGATLMLTWWWQASRLNLPRQQKATMQEIWHSFVSGIW
                     ALFLPVIIIGGFRSGLFTPTEAGAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTS
                     VVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIMVAILIVGMVMDLTP
                     TVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDA
                     VRGVFPYVLVLYSLLVVFVFIPDLIILPLKWIN"
     gene            23838..>24198
                     /gene="yiaO"
                     /locus_tag="IT892_002983"
     CDS             23838..>24198
                     /gene="yiaO"
                     /locus_tag="IT892_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter
                     substrate-binding protein YiaO"
                     /protein_id="HAP3136175.1"
                     /translation="MKLRSVTYALFIAGLAAFSTSSLAAQSLRFGYETSQTDSQHIAA
                     KKFNDLLQERTKGELKLKLFPDSTLGNAQAMISGVRGGTIDMEMSGSNNFAGLSPVMN
                     LLDVPFLFRDTAHAHKTL"
BASE COUNT         6011 a         6140 c         5939 g         6108 t
ORIGIN      
        1 tattaaaggt tgctgtatta tttagcgata aaaaaagcct gccagatggc aggctattta
       61 ataacggcgt tattattgca acagcgaaat atccgcaacg cgcaggaaca gttcgcgcag
      121 tttctccagc atggtcagac ggttgatacg caattctttg tcatcaacca tgaccatcac
      181 tttatcgaag aaagcatcaa ccggttcacg cagctcagcc agttcgacca gcgcatcctg
      241 gtaacgacct tccgtaaagt acggctccag cttgtcacgt agcaccacaa cctgcatcgc
      301 cagtttaatt tcttccggct ctttcagggt agaggcattc acgcggtcgc tcagcacttc
      361 gtcagatttc gccagaatgt tagatacacg tttgttcgcc gccgccagtg cagcagctgc
      421 atccagggta cggaaatgcg ataccgcttt catacgggca tcgaaatcag ccggacgagt
      481 cggacgacgc gccagtaccg cctggatggt gtcaacggta taaccttcgt cctgatacca
      541 ggcgcggaag cgaccgagca taaagtcgat aacatcatca actacgttgg cattagtcag
      601 cttatcgcca tacagacgca ccgcttcttc ggtcagcgtt tgcagatcaa ggttgaggtt
      661 cttctcaacg ataattcgca gcacgccaag cgcggcacga cgcagcgcaa acgggtcttt
      721 gtcgcctttc ggatgctgac cgataccgaa gatacccgcc agggtatcca tcttgtcagc
      781 aatcgccagc gcacaagcta ctgggttgga cggcaggtca tcaccagcaa aacgcggctg
      841 atactgctca ttcagcgcca ccgcgacatc ttccgcttcg ccatcgtgac gcgcatagtg
      901 catccccata acgccctggg tgtcggtgaa ctcgaagacc atgttggtca tcaggtcgca
      961 cttagacagc agacccgcac gggtagcgtg gttaacgtca gcgccaatct gttcagcaat
     1021 ccagccagcc agcgcctgga tgcggtcagt tttgtcgcgc agcgtcccca actgttgctg
     1081 gaacaacacg gtttgcaggc gcggcaggtt atcttcaaga cgttttttac ggtcggtgtt
     1141 gaagaagaac tcggcatccg ccagacgcgg acgaacgact ttctcgttac cggagataat
     1201 ctgctgcgga tctttcgatt cgatgttggc aacgaagata aagttcggca gcagtttgcc
     1261 gtcgttcgca tacaccggga agtatttctg gtcacctttc atggtgtaaa ccagcgcttc
     1321 agccggcacc gcgaggaatt tctcttcgaa ttttgcggtc agaacgaccg gccactccac
     1381 cagcgaagcc acttcttcca gcaggctttc gcttaagtca gcgttaccgc caatcttacg
     1441 cgctgcttct tcggcatcgg ctttaatctt cgccttacgt tcttcgtaat cggcgatgac
     1501 tttcccacgc tcacgcagaa tttccggata ctgatcggcg ttatcgatgg tgaattccgg
     1561 ctcgcccata aagcggtggc cgcgaatcac gcgatcggac tgaatgccca gaatggttgc
     1621 cggaatgact ttgtcgccca gcagcagggt cacggtgtgc accggacgca cgaagtgcac
     1681 gtcgcttgcg ccccaacgca tcagtttcgg gatcggcagt ttcgccagag aagtcgcaac
     1741 catattcggc agcagtgctt cggtgctttc gcccttcaca tgggcgcgat acagcagcca
     1801 ttcgccttta tcggtagtca gacgctcagc ctggtcaacg gtaataccgc aaccacgcgc
     1861 ccaaccttct gccgctttgc tcggtttgcc ttcagcgtcg aacgcctggg caatcgccgg
     1921 gccgcgcttt tcgatttcac gatccggttg cgcttccgcc aggttagcta ctttcagcgc
     1981 cagacgacgc ggagcagcaa accattgaac ggtgccgtgt gcgaggccag cgttatccag
     2041 ctccgcagta aagttcgcag caaaggactc agccaggctg cgcagtgctt ttggtggcag
     2101 ctcttcagtg ccgatttcca ccagaaaagt tttctcagac atagccgcct cttacttatc
     2161 tttgttgcac atcgggaagc cgagggcttc acgggaagcg tagtatgctt ctgccactgc
     2221 tttggtcagg gtgcgaatgc gcagaatgta gcgctgacgc tcggtgacgg agatggcttt
     2281 acgcgcatcc agcaggttga agctgtgggc ggctttcaga atacgctcgt aggctggcag
     2341 cggcagcgga ttttccagcg ccagcagctg ctgcgcttct ttctcgtact gctcgaagca
     2401 ggtgaacagg aagtccacat ccgcgtattc gaagttgtaa gtggactgct ccacttcgtt
     2461 ctgatggaac acgtcgccgt aggtggtttt acccagcggg ccgtcgctcc agaccaggtc
     2521 gtaaacgctg tctacgccct gaatgtacat ggccagacgt tccagaccgt aggtgatctc
     2581 gccggtaacc ggtttacact ccagaccacc aacctgctgg aagtaagtga actgcgtcac
     2641 ttccatgccg ttcagccaca cttcccagcc cagtccccag gcacccagcg tcgggttttc
     2701 ccagttatct tccacgaaac ggatgtcgtg aatagtcggg tccatgccca gctctttcag
     2761 agaaccgagg tacagctcct gaatattgtc cggcgatggc ttaatgacca cctggaactg
     2821 atagtagtgc tgtaaacggt tggggttttc gccgtagcga ccatcggtcg ggcgacgaga
     2881 aggctgaaca taagcagccg ccatcggttc tggccccagc gcgcgcagac aggtcattgg
     2941 gtgagaggtt cccgcgccga cttccatgtc caatggttga acaatggtgc agccctggcg
     3001 agcccagtaa tcctgtaagg tcaggatcaa gccctggaag gtcctggtat caaacttttg
     3061 catattattt cgtgctggat acgtgtggat ttaaaggaag ggatcagtat acccgctgga
     3121 tggaagatat acagtacgaa acgggaaaaa gcagggctta acgcatggaa agatgcaaaa
     3181 aatggccatc cgcgtcaaaa gaacagacaa actgctcttt acggaaggta taaccgcgca
     3241 tttcatagct tccctggaac tgttcgaagg cggtgacgtc gattttttgc tcgccggtgt
     3301 tataacgttt tgccgcctga tccttgcata acgcttccat attcaacgaa cgcagaggat
     3361 caacctttac ccgttgtgct ttctgcacgg gtgacggtat agaacaaccc actagcacca
     3421 taagcgccat tgccggaaag aaagcgttca tcatcattaa attaccgtct ggtttgcagg
     3481 tgagtcttat tatttatatc ggtatagtgg ctgatatctt acgaatttcc ttaagcctct
     3541 ataagctgta gtgataaaac tcagattatt ccagtgcgcc aaccaaatga tttatcggtc
     3601 agactttttt aaccagatac agagacacag atgcagccca aaatttactg gattgataac
     3661 ctgcgaggga tagcgtgttt aatggtggtg atgattcaca ccactacctg gtatgtgacc
     3721 aatgctcata gtgttagccc cgtcacatgg gatatcgcca atgttctgaa ttctgcctct
     3781 cgtgtcagcg tgccgctatt tttcatgatt tccggctatc tcttttttgg cgaacgcagc
     3841 gcccagccgc gccatttctt gcgtatcggc ttatgtctga ttttttatag cgcaatcgca
     3901 ctgctctaca ttgcgctgtt tacctccatc aatatggagt tagcgctgaa aaacctgctg
     3961 caaaagccag tgttttacca cttgtggttt ttcttcgcga ttgcggtgat ttatctggtt
     4021 tcaccgctga ttcaggtgaa gaacgtcggc ggaaaaatgt tgctggtgct aatggcggtg
     4081 attggcatta tcgctaaccc aaacacagtg ccgcagaaaa ttgacggttt tgaatggctg
     4141 ccaattaact tatatatcaa tggcgatact ttttactaca ttctgtatgg catgttgggc
     4201 cgcgctatag ggatgatgga cacacagcat aaagcactgt cgtgggtgag cgccgcgctg
     4261 tttgcgacgg gggtttttat tatctctcgc gggacattat atgaattgca gtggcgcgga
     4321 aattttgccg atacctggta tctttactgt gggccgatgg tttttatctg cgcaatcgcg
     4381 ctattgactc tggttaaaaa cacgctggat acgcgtacca ttcgcggact tggcttaatc
     4441 tcccgccatt cattgggtat atacggattc cacgccttga ttatccatgc gctgcgcacc
     4501 cggggaattg agcttaaaaa ttggccaata ctggatatta tttggatctt ttgcgcgacg
     4561 ttggcagcga gtttgttact ttctatgctg gtacaacgaa tcgacagaaa cagattagtg
     4621 agttaagtaa aagcccggtc acattggact gaccgggctt acgtgagtta ttcgctgtat
     4681 tcttcctggg taacctgtgt ttcttttggt gggtttattc cggcatcacg aatatttttc
     4741 tgcaccgcta ctgcaccaaa caagcttaag aagaaagcca gtccataaaa acctttttcg
     4801 ctgagtaata atgtcgcatt ccacagacct accatcagta atgcaacaga gataataaag
     4861 acagtcaggc aggtcatata ataaatggaa gtggtcggta tgccttcata cttgtcccga
     4921 acggtctttt gataagacgc cgcagaaaac agtcctaata ccagtacggc aaaataatat
     4981 cctttttcat ttaactgcat ctctgcattc catagcccta acagataggt aacgatacca
     5041 ccaacgagag ctatccatga cacaatacta aaggccggtg aataggttga tattttgttg
     5101 tccatcacag tattcctttc attcctgaat atgtaagagc tttatgttgc tcatgccgag
     5161 cgaaacaaac gcatttgacc aaacaagcag acaaaaaagg cgatgggata gatcaccatt
     5221 tcataagtat tgataggtgc gtttaaaaca ccgataaaca agagaccgat agtgattaac
     5281 gcaactaact ggcagatatg ggtaaaaaaa tcatccagtt gcccgagttt ttctgcgcga
     5341 agatatgcat agttgccaaa agttgctgtc attaacacgc caagaaaata gccttttcca
     5401 cttaacaatg ggcatgagat ccatagccca accagataaa ccagcgcccc gacaacaaat
     5461 aatagttttg ccacagtctt tgaggttttc ataacgatct ccatatctac cagcgataca
     5521 ttacgagtaa ccaacgaaag acaaaactga aaaatgccat taacaaatga ttttcagaat
     5581 aaattcatac taaatattaa ttaattactg agatatatag atgtgaatta tcccccaccc
     5641 ggtcaggcag gggataacgt ttacgccatt aatggcagaa gttgctgata gaggcgacgg
     5701 aacgtttctc gtcgtggctg ataagcggca taacgctgcg catctggtag atgcgactgt
     5761 tctaacggta gttgcggcaa caattcaatg agcgatttct ctggattcgc cgcgatctgc
     5821 gccagccttg ctgcgcccag tgctggcccc acatcccccc ccgtacggta atcgagctgc
     5881 tgaccgctga tatccgccag catctgacgc cagtactcac tacgcgcccc gcccccaatc
     5941 aacgtaacac tttgcggttt aataccgcag gcatgcacga catccatgcc atctgccagc
     6001 gcataaccca cgccttccag cactgctcgc gccagttcat tggggccatg ttgatgagtc
     6061 aaaccaaaga aaaccccctt cgcctgggga ttattgtgtg gcgtacgctc gccggaaaga
     6121 taaggcagaa accaaactgg ctcggcactt tcatcagcct gttgagctgc agcgattaaa
     6181 gctgggacat tgctcaggcc ggttaatttc gcggcccaat ccagacacga cgctgcactc
     6241 agcatcacag acattaaatg ccaacgttgc ggtagcgcat ggcaaaagct atgtacggcg
     6301 ctttctggct tgcttaagaa cccttcgctg acagcaaaat agacccccga cgtccccagc
     6361 gataacattg cctgattagc atcaaccatt cccacaccaa ctgcaccagc tgcattgtcg
     6421 ccaccgcctg cgacaactgg caccgtcgcc ataccccacg ctttcgcaac ttcaggtaac
     6481 aaagcaccag taatttcgct gccttcgtat aatgcgggca tctggtcacg agataagtcg
     6541 caagcctgca gcatgacgtc actccagtca cgctttgcga catccagcca catggtgcca
     6601 gctgcgtcag acatatcgct ggcaaactcc cccgtcatac gcagacgcaa gtaatctttc
     6661 ggtaataata ctttgtcgat ttgacggaat atctccggct catgccgctg aacccatagc
     6721 aatttaggcg cagtaaatcc gggcatcatc aggttgccgg taatcacccg cgattgcgga
     6781 actcgcgctt ccagcaaagt gcactcttgc gcacagcgcc cgtcgttcca caaaatggca
     6841 gggcgtaaca cccgttgctg agcatccagc aaggttgctc cgtgcatctg gccggcaata
     6901 cccaatgctt taacgtcctg cagagaatgc tgatcgccca gagctttcat tgcgcgatca
     6961 gttgcctgcc accactgttc cgggtcttgt tccgaccaga gtggatgcgg gcgcgaaacg
     7021 gtcagctttt ccgtttgcgc agcaaccacc tcaccctgct cgttgagcaa aataactttt
     7081 acgcccgagg tgccaagatc tatcccgata tacatatcga tcgttcctta aaaaaatgcc
     7141 cggtatcgct accgataacc gggccaacgg actgcacagt tagccgttat ttgtcgaaca
     7201 gataatggtt taccagattt tccagttgtt cctggcgacc actctgatgc accggagaca
     7261 aatgatgttc ctgagcatat ttggctaaat ctgccagtga catttggcct ttcaggattt
     7321 gctggcccaa ttcgctattc cagccggaat aacgctgcgc gatgcgttta tccagctcgc
     7381 catcttcaat catgcgcgct gcaattttca gcgccagtgc catcgtatcc atcgcgccga
     7441 tatgaccgta aaacagatca tatttatcag tactttgacg acgtactttg gcatcgaagt
     7501 tcagaccacc ggtggtgaaa ccgcctgctt tgagaatttc atacatcacc agcgcattct
     7561 cttccacact gttcgggaac tggtcggtgt cccagcccag ttgcgcatcg ccacggttgg
     7621 cgtcgacaga accgaacagg ccaagcgcaa tggcggtggc tatttcatga tggaaagagt
     7681 gacctgccag cgtcgcgtgg ttagcttcaa tgttcagttt aatctctttt tccagaccaa
     7741 actgtttcag gaagccatag accgtcgcgg catcgtaatc atattgatgt ttggtcggtt
     7801 cttgcggttt cggttcgata agcaacgtgc cctggaaacc gattttatgt ttatgctcaa
     7861 ccaccatctg cataaagcgg cccagttgtt cacgctcctg acgcaagtcg gtatttaaca
     7921 gcgtttcgta accttcacga ccgccccaca ggacatagtt ttcaccgccc aatttatggg
     7981 ttgcttccat cgctgtaaca acttgcgttg ccgcccagct gaagacttca ggatctgggt
     8041 tcgtcgccgc acccgcgccg tagcgagggt ttgtaaagca gttggcggtt ccccacagca
     8101 gcttcacgcc gctctcttct tgcttgcctg ccaggacatc aaccatttgc gcaaaattat
     8161 tgatgtactc ttttaacgac gcgccctcag gggaaacatc cacatcgtgg aagcaataaa
     8221 atggcacatg taacttgtgg aaaaactcaa atgcgacatc tgctttacgc ttcgccaacg
     8281 ccagtgcctc accaggctgc tgccacggac gattaaacgc ccccacacca aacatatccg
     8341 ccccgttcca gcagaaggtg tgccagtagc aggcggcaaa acgcaagtgc tcttccatac
     8401 gcttacccaa caccagttcg tcgggattgt agtgacggaa tgctaacggg tttgaggatt
     8461 ttgagccttc ataacgaacg cgatcgagct ggtcaaaata ggcttgcata ttgaactcca
     8521 taatcaggta atgccgcggg tgatggatga tgtcgtaata ttgggcactc cctttcagtt
     8581 gctcaattat gttatttcac actgctattg agataattca caagtgtgcg ctcgctcgca
     8641 aaataaaatg gaatgatgaa actgggtaat tcctcgaaga gaaaaatgca ataagtacaa
     8701 ttgcgcaaca aaagtaagat ctcggtcata aatcaagaaa taaaccaaaa atcgtaatcg
     8761 aaagataaaa atctgtaatt gttttcccct gtttagttgc taaaaattgg ttacgtttat
     8821 cgcggtgatt gttacttatt aaaactgtcc tctaactgca gaaggcccta caccatgaaa
     8881 ataaagaaca ttctactcac cctttgcacc tcactcctgc ttaccaacgt tgctgcacac
     8941 gccaaagaag tcaaaatagg tatggcgatt gatgatctcc gtcttgaacg ctggcaaaaa
     9001 gatcgagata tctttgtgaa aaaggcagaa tctctcggcg cgaaagtatt tgtacagtct
     9061 gcaaatggca atgaagaaac acaaatgtcg cagattgaaa acatgataaa ccggggtgtc
     9121 gatgttcttg tcattattcc gtataacggt caggtattaa gtaacgttgt aaaagaagcc
     9181 aaacaagaag gcattaaagt attagcttac gaccgtatga ttaacgatgc ggatatcgat
     9241 ttttatattt ctttcgataa cgaaaaagtc ggtgaactgc aggcaaaagc cctggtcgat
     9301 attgttccgc aaggtaatta cttcctgatg ggcggctcgc cggtagataa caacgccaag
     9361 ctgttccgcg ccggacaaat gaaagtgtta aaaccttacg ttgattccgg aaaaattaaa
     9421 gtcgttggtg accaatgggt tgatggctgg ttaccggaaa acgcattgaa aattatggaa
     9481 aacgcgctaa ccgccaataa taacaaaatt gatgctgtag ttgcctcaaa cgatgccacc
     9541 gcaggtgggg caattcaggc attaagcgcg caaggtttat cagggaaagt agcaatctca
     9601 ggccaggatg cggatctcgc aggtattaaa cgtattgctg ccggtacgca aactatgacg
     9661 gtgtataaac ctattacgtt gttggcaaat actgccgcag aaattgccgt tgagttgggc
     9721 aatggtcagg aaccaaaagc agataccaca ctgaataatg gcctgaaaga tgtcccctcc
     9781 cgcctcctga caccgatcga tgtgaataaa aacaacatca aagatacggt aattaaagac
     9841 ggattccaca aagagagcga gctgtaagcg ttacgcccca gcgcggagcg ggggcgtgat
     9901 ttctctccat gccgcgtgaa tgaattggct taggtggagt cgttatgcct tatctacttg
     9961 aaatgaagaa cattaccaaa accttcggca gtgtgaaggc gattgataac gtctgcttgc
    10021 ggttgaatgc tggcgaaatc gtctcacttt gtggggaaaa tgggtctggt aaatcaacgc
    10081 tgatgaaagt gctgtgtggt atttatcccc atggctccta cgaaggcgaa attatttttg
    10141 cgggagaaga gattcaggcg agtcacatcc gcgataccga acgcaaaggt atcgccatca
    10201 ttcatcagga attggccctg gtgaaagaat tgaccgtgct ggaaaatatc ttcctgggta
    10261 acgaaataac ccacaatggc attatggatt atgacctgat gacgctacgc tgtcagaagc
    10321 tgctcgcaca ggtcagttta tccatttcac ctgatacccg cgttggcgat ttagggcttg
    10381 ggcaacaaca actggttgaa attgccaagg cacttaataa acaggtgcgc ttgttaattc
    10441 tcgatgaacc gacagcctca ttaactgagc aggaaacgtc ggttttactg gatattattc
    10501 gcgatctaca acagcacggt atcgcctgta tttatatttc gcacaaactc aacgaagtca
    10561 aagcgatttc cgatacgatt tgcgttattc gcgacggaca gcacattggt acgcgtgatg
    10621 ctgccggaat gagtgaagac gatattatca ccatgatggt cgggcgagag ttaaccgcgc
    10681 tttaccctaa tgaaccacat accaccggag atgaaatatt acgtattgaa catctgacgg
    10741 catggcatcc ggttaatcgt catattaaac gagttaatga tgtctcgttt tccctgaaac
    10801 gtggcgaaat attgggtatt gccggactcg ttggtgccgg acgtaccgag accattcagt
    10861 gcctgtttgg tgtgtggccc ggacaatggg aaggaaaaat ttatattgat ggcaaacagg
    10921 tagatattcg taactgtcag caagccatcg cccaggggat tgcgatggtc cccgaagaca
    10981 gaaagcgcga cggcatcgtt ccggtaatgg cggttggtaa aaatattacc ctcgccgcac
    11041 tcaataaatt taccggtggc attagccagc ttgatgacgc ggcagagcaa aaatgtattc
    11101 tggaatcaat ccagcaactc aaagttaaaa cgtcgtcccc cgaccttgct attggacgtt
    11161 tgagcggcgg caatcagcaa aaagcgatcc tcgctcgctg tctgttactt aacccgcgca
    11221 ttctcattct tgatgaaccc accaggggta tcgatattgg cgcgaaatac gagatctaca
    11281 aattaattaa ccaactcgtc cagcagggta ttgccgttat tgtcatctct tccgaattac
    11341 ctgaagtgct cggccttagc gatcgtgtac tggtgatgca tgaagggaaa ctaaaagcca
    11401 acctgataaa tcataacctg actcaggagc aggtgatgga agccgcattg aggagcgaac
    11461 atcatgtcga aaagcaatcc gtctgaagtg aaattggccg taccgacatc cggtggcttc
    11521 tccgggctga aatcactgaa tttgcaggtc ttcgtgatga ttgcagctat catcgcaatc
    11581 atgctgttct ttacctggac caccgatggt gcctacttaa gcgcccgtaa cgtctccaac
    11641 ctgttacgcc agaccgcgat taccggcatc ctcgcggtag gaatggtgtt cgtcataatt
    11701 tctgctgaaa tcgacctttc cgtcggctca atgatggggc tgttaggtgg cgtcgcggcg
    11761 atttgtgacg tctggttagg ctggcctttg ccacttacca tcattgtgac gctggttctg
    11821 ggactgcttc tcggtgcctg gaacggatgg tgggtcgcgt accgtaaagt cccttcattt
    11881 attgtcaccc tcgcgggcat gttggcattt cgcggcatac tcattggcat caccaacggc
    11941 acgactgtat cccccaccag cgccgcgatg tcacaaattg ggcaaagcta tctccccgcc
    12001 agtaccggct tcatcattgg cgcgcttggc ttaatggctt ttgttggttg gcaatggcgc
    12061 ggaagaatgc gccgtcaggc tttgggttta cagtctccgg cctctaccgc agtagtcggt
    12121 cgccaggctt taaccgctat catcgtatta ggcgcaatct ggctgttgaa tgattaccgt
    12181 ggcgttccca ctcctgttct gctgctgacg ttgctgttac tcggcggaat gtttatggca
    12241 acgcggacgg catttggacg acgcatttat gccatcggcg gcaatctgga agcagcacgt
    12301 ctctccggga ttaacgttga acgcaccaaa cttgccgtgt tcgcgattaa cggattaatg
    12361 gtagccatcg ccggattaat ccttagttct cgacttggcg ctggttcacc ttctgcggga
    12421 aatatcgccg aactggacgc aattgcagca tgcgtgattg gcggcaccag cctggctggc
    12481 ggtgtgggaa gcgttgccgg agcagtaatg ggggcattta tcatggcttc actggataac
    12541 ggcatgagta tgatggatgt accgaccttc tggcagtata tcgttaaagg tgcgattctg
    12601 ttgctggcag tatggatgga ctccgcaacc aaacgccgtt cttgattttg ataaaaattt
    12661 tctcaaagcc ggttacgtat taccggtttt gagtttttgc atgattcagc aggaaaagaa
    12721 ccatgtttac taaacgtcac cgcatcacat tactgttcaa tgccaataaa gcctatgacc
    12781 ggcaggtagt agaaggcgta ggggaatatt tacaggcgtc acaatcggaa tgggatattt
    12841 tcattgaaga agatttccgc gcccgcattg ataaaatcaa ggactggtta ggagatggcg
    12901 tcattgccga cttcgacgac aaacagatcg agcaagcgct ggctgatgtc gacgtcccca
    12961 ttgttggggt tggcggctcg tatcaccttg cagaaagtta cccacccgtt cattacattg
    13021 ccaccgataa ctatgcgctg gttgaaagcg catttttgca tttaaaagag aaaggcgtta
    13081 accgctttgc tttttatggt cttccggaat caagcggcaa acgttgggcc actgagcgcg
    13141 aatatgcatt tcgtcagctt gtcgccgaag aaaagtatcg cggagtggtt tatcaggggt
    13201 tagaaaccgc gccagagaac tggcaacacg cgcaaaatcg gctggcagac tggctacaaa
    13261 cgctaccacc gcaaaccggg attattgccg ttactgacgc ccgagcgcgg catattctgc
    13321 aagtatgtga acatctacat attcccgtac cggaaaaatt atgcgtgatt ggcatcgata
    13381 acgaagaact gacccgctat ctgtcgcgtg tcgccctttc ttcggtcgct cagggcgcgc
    13441 ggcaaatggg ctatcaggcg gcaaaactgt tgcatcgatt attagataaa gaagaaatgc
    13501 cgctacagcg aattttggtc ccaccagttc gcgtcattga acggcgctca acagattatc
    13561 gctcgctgac cgatcccgcc gttattcagg ccatgcatta cattcgtaat cacgcctgta
    13621 aagggattaa agtggatcag gtactggatg cggtcgggat ctcgcgctcc aatcttgaga
    13681 agcgttttaa agaagaggtg ggtgaaacca tccatgccat gattcatgcc gagaagctgg
    13741 agaaagcgcg cagtctgctg atttcaacca ccttgtcgat caatgagata tcgcaaatgt
    13801 gcggttatcc atcgctgcaa tatttctact ctgtttttaa aaaagcatat gacacgacgc
    13861 caaaagagta tcgcgatgta aatagcgagg tcatgttgta gcgatgatga gaattgtcgg
    13921 cgtcacatca ggtaacgctg cgtggttgtc ggatgcggcg tgaacgcctt atccgaccta
    13981 cccgccaggc atgataaaac gcaccaacaa cgcttcaggc tcgtagctca actgcctgag
    14041 acaaagtaaa aagccttatc cgactgacaa gtcggataag gctcaaggaa atgcaattac
    14101 atatgcgccg cgattaaccg ttggttatcc tggtacattg cgaacaggta gttgttataa
    14161 ctcttccctt tggtcgagta gcccttcagc ttgtgaatca tcgctgtggc agtcacttcc
    14221 tgatccgctt tacgcagctg cgcacgcgat ttacggaacg aagagtaagc cgggtgcgta
    14281 ttcaggttag tgacataggc gctcaccgat tctttgacag aactaaactg tgagtaccct
    14341 ttcactttac ctggcgcatt ggtacaacgt cctttcatgc atttcatgcc gaacaggttg
    14401 ttgttgttgc gcgccagctt cgacgttccc caaccgcttt ctgctgcagc catcgtcgcc
    14461 accatactgg tggggataat gtctacgcgt tcaagcaagg tattccacgg gatttttcgc
    14521 gtattaccgg accacttcac cttgtagcgt ttggcgatgt ctttcagacg cgcacgctca
    14581 gcaggtgacc attggccctg atactgtttt gaaatgagcc agttacgttc cgcagtaatg
    14641 gccgcatttt ggctggtaat gtaaggcatt acggtccgga gaaacgcctt tttccttggt
    14701 gttccggaag ggtattttcg caaatcagga agtgaactac tctttgcact attgcgagaa
    14761 tactcttgtt tactgcttac ctgtttatta ctagctttag ttaagtggga cttttgactc
    14821 gctgttgttg tgtgcgtctt cgctaacacc tcactcgaaa acaccagagt gagtaacata
    14881 agaatcatcg ccccatatcg tcgtatggga gtcaaaatca tcaggtctcc tggtcggatt
    14941 taatcattcc aacaccttat atttttcaca aatttgagag ttgaatctca aatcatatca
    15001 aaaatagctg tcaagagcac cccaaggaat agtccaaatc tgaaactatg tcacgtgtta
    15061 acgattcaga ttggcgctaa atcgcagaaa atgtgggggt tatcgcaaaa ttcagccgtt
    15121 ttttgcgcga gatcgctcac ccttgcttct catcctgtgg acttaccgct cagggatgag
    15181 ttttgtttgg cttatcgctg gcaaactgtc tgaaatcgca gcaataagga ctcatccgcc
    15241 atgaaactcg ccgcctgttt tctgacactc cttcctggct tcgccgttgc cgccagctgg
    15301 acttctccgg ggtttcccgc ctttagcgaa caggggacag gaacatttgt cagccacgcg
    15361 cagttgccca aaggtacgcg tccactaacg ctaaattttg accaacagtg ctggcagcct
    15421 gcggatgcga taaaactcaa tcagatgctt tccctgcaac cttgtagcaa cacgccgcct
    15481 caatggcgat tgttcaggga cggcgaatat acgctgcaaa tagacacccg ctccggtacg
    15541 ccaacattga tgatttccat ccagaacgcc gccgaaccgg tagcaagcct ggtccgtgaa
    15601 tgcccgaaat gggatggatt accgctcaca gtggatgtca gcgccacttt cccggaagga
    15661 gccgccgtac gggattatta cagccagcaa attgcgatag tgaagaacgg tcaaataatg
    15721 ttacaacccg ctgccaccag caacggttta ctcctgctgg aacgggcaga aactgacaca
    15781 tccgcccctt tcgactggca taacgccacg gtttactttg tgctgacaga tcgtttcgaa
    15841 aacggcgatc ccagtaatga ccagagttac ggacgtcata aagacggtat ggcggaaatt
    15901 ggcacttttc acggcggcga tttacgcggc ctgaccaaca aactggatta cctccagcag
    15961 ttgggcgtta atgctttatg gataagcgcc ccatttgagc aaattcacgg ctgggtcggc
    16021 ggcggtacaa aaggcgattt cccgcattat gcctaccacg gttattacac acaggactgg
    16081 acgaatcttg atgccaatat gggcaacgaa gccgatctac ggacgctggt tgatagcgca
    16141 catcagcgcg gtattcgtat tctctttgat gtcgtgatga accacaccgg ctatgccacg
    16201 ctggcggata tgcaggagta tcagtttggc gcgttatatc tttctggtaa cgaagtgaaa
    16261 aaatcgctgg gtgaacgctg gagcgactgg aaacctgccg ccgggcaaac ctggcatagc
    16321 tttaacgatt acattaattt cagcgacaaa acaggctggg ataaatggtg gggaaaaaac
    16381 tggatcagaa cggatatcgg cgattacgac aatcctggat tcgacgatct cactatgtcg
    16441 ctagcctttt tgccggatat caaaaccgaa tcaactaccg cttctggtct gccggtgttc
    16501 tataaaaaca aaatggatac ccacgccaaa gccattgacg gctatacgcc gcgcgattac
    16561 ttaacccact ggttaagtca gtgggtccgc gactatggga ttgatggttt tcgggtcgat
    16621 accgccaaac atgttgagtt gcccgcctgg cagcaactga aaaccgaagc cagcgccgcg
    16681 cttcgcgaat ggaaaaaagc taaccccgac aaagcattag atgacaaacc tttctggatg
    16741 accggtgaag cctggggcca cggcgtgatg caaagtgact actatcgcca cggcttcgat
    16801 gcgatgatca atttcgatta tcaggagcag gcggcgaaag cagtcgactg tctggcgcag
    16861 atggatacga cctggcagca aatggcggag aaattgcagg gtttcaacgt gttgagctac
    16921 ctctcgtcgc atgatacccg cctgttccgt gaagggggcg acaaagcagc agagttatta
    16981 ctattagcgc caggcgcggt acaaatcttt tatggtgatg aatcctcgcg tccgttcggt
    17041 cctacaggtt ctgatccgct gcaaggtaca cgttcggata tgaactggca ggatgttagc
    17101 ggtaaatctg ccgccagcgt cgcgcactgg cagaaaatca gccagttccg cgcccgccat
    17161 cccgcaattg gcgcgggcaa acaaacgaca cttttgctga agcagggcta cggctttgtt
    17221 cgtgagcatg gcgacgataa agtgctggtc gtctgggcag ggcaacagta acttttccgg
    17281 cttcccgttc gtcagtacct cgggaagccg ccaaccagga taaaatgtca gccctaatca
    17341 gcgttgcagg ataaagcacc gctcactctt caacagaccg atttgcaccc cagcaaatgt
    17401 agcgttattg ttaccttcct tgctacagag ttcgacagat atcccgctat gacattctcc
    17461 ctttttggtg acaaatttac ccgccactcc ggcattacgc tgttgatgga agatctgaac
    17521 gacggtttac gcacgcctgg cgcgattatg ctcggcggcg gtaatccggc gcagatcccg
    17581 gaaatgcagg actacttcca gacgctactg accgacatgc tggaaagtgg caaagcgact
    17641 gatgcactgt gtaactacga cggtccacag gggaaaacgg agctactcac actgcttgcc
    17701 ggaatgctgc gcgagaagtt gggttgggat atcgaaccac agaatattgc actaacaaac
    17761 ggcagccaga gcgcgttttt ctacttattt aacctgtttg ccggacgccg tgccgatggt
    17821 cgggtcaaaa aagtgctgtt cccgcttgca ccggaataca ttggctatgc tgacgccgga
    17881 ctggaagaag atctgtttgt ctctgcgcgt ccgaatattg aactgctgcc ggaaggccag
    17941 tttaaatacc acgtcgattt tgagcatctg catattggcg aagaaaccgg gatgatttgc
    18001 gtctcccggc cgacgaatcc aacaggcaat gtgattactg acgaagagtt gctgaagctt
    18061 gacgcgctgg cgaatcaaca cggcattccg ctggtgattg ataacgctta tggcgtcccg
    18121 ttcccgggta tcatcttcag tgaagcgcgc ccgctatgga atccgaatat cgtgctgtgc
    18181 atgagtcttt ccaagctggg tctacctggc tcccgctgcg gcattatcat cgccaatgaa
    18241 aaaatcatca ccgccatcac caatatgaac ggcattatca gcctggcacc tggcggtatt
    18301 ggtccggcga tgatgtgtga aatgattaag cgtaacgatc tgctgcgcct gtctgaaaca
    18361 gtcatcaaac cgttttacta ccagcgtgtt caggaaacta tcgccatcat tcgccgctat
    18421 ttaccggaaa atcgctgcct gattcataaa ccggaaggag ccatttttct ctggctatgg
    18481 tttaaggatt tgcccattac gaccgagcag ctctatcagc gcctgaaagc acgcggcgtg
    18541 ctgatggtgc cggggcacaa cttcttccca gggctggata aaccgtggcc gcatacgcat
    18601 caatgtatgc gcatgaacta cgtaccagag ccggagaaaa ttgaggcggg ggtgaagatt
    18661 ctggcggaag agatagaaag agcctgggct gaaagtcact aaaaattgcc tgatgcgcta
    18721 cgcttatcag gcctacatga tttctgcaat atattgaatt tggaagaatt tgtaggccgg
    18781 ataaggcgtt tacgccgcat ctggcataaa caaagcgcac tgttccggcg ttgagaaacg
    18841 ccggaaaacg tttcaaacag gctgctgccg tagccgatgc cgctgcactt tctcgacatc
    18901 catgcactgc aacgcctttg tcgggcaggc ttcaacacag gccggtcccg tctcccgatg
    18961 ccagcacaga tcgcacttaa tcgccctcgc ctttttgcgc gaagaaacga cctccatcgc
    19021 accaaacggg caagccagca tacagctttt acagccaatg caacgtgttt gttcaacgaa
    19081 aatatgccca tgttcgcggc ttatcgcgtc aacagggcag acattcgcgc acggtgcatc
    19141 ttcacactga tgacaggcta ctgccgtggt ccagcagtgg tctttaatga cacgaatacg
    19201 ggaaataaac tcgtctggtg acaacgcagc gcaatcctga ttctcatgat gcgacactgc
    19261 gcaagccact tcacaggtac ggcaaccgat acatttcgtc gcatccgcaa taataaaccg
    19321 gttcatgatc actcctttgc actaaaacag cagagtgcca gagagcgcgt ccctactgct
    19381 ttgatccaac gaaggaaatg ttaaagtttt ggcacttgtc caaagcgtta tgtgatcgcg
    19441 cccaggtcat ccctgacagt aaatcccagt tcattagaaa tagcctgcgc ggtttcacgc
    19501 agtggtttca ggagattttt ctctcccacc tgtttcagac gtgatgtcga aagcgaaatc
    19561 gacacggcgt acggcacccg cccatgaata tcaaacaccg gaacagcaat acaggagacg
    19621 ccgagttcgt tttcttctct gtccatcgcc gctccgcttt cacgaatgtg cgccagttcg
    19681 tcgaacatcg cgggcagctc ggtaatggta ttgcgggtta acggctggat ctcatgctga
    19741 tggctttccc agtatgactt cacgtagtcc gggtgaccaa acgccatgta gatcttgccc
    19801 attgcggaac agtagagcgg catatgctgg ccaatatagg cacgggttcg cagcatcccg
    19861 gttgtgggtt ccagcttata aatcaaaata gcgtgatcgt cttcgcggct ggagaagtta
    19921 atggtttcac cagtggcgat gttcagtgcc tcaagatgcg gagcggcgat atgaatgata
    19981 ttcagcgaag acagcgcctt ctgcccgacg gcaataaatt tggtggtcag gcgataactc
    20041 cctgcggcag gcgcggtggt cacatagccg caggactgta atccctgcaa taagcgatgg
    20101 acggtactct tatttaaacc agccagctcc gaaagatgcg ccaacggaca accgtttgga
    20161 tagttgctca aaatctcaat cagcatcaac ccgcgaaaca gactctggct tccggctgga
    20221 cgctcttttt cctgcgccat ctcgttctct ttttttccca tcacttcttt ccccattttg
    20281 tcgcgtcctg atggtagcgc aaagtgtgcc gtagttcacg atctcgacag ataatttata
    20341 accaattgat ttttatgtct tttgaaattc atcaatcaga ttgctttgtt aaaaagtgat
    20401 cgatatattt gaaatcaagt ttcgcatatt gaaattttaa gccaaaaaag cgatcaaaaa
    20461 aacaaggaag cctgggatga aagtgacatt tgagcagtta aaagcagcct ttaatcgggt
    20521 cttaatttca cgcggcgttg acagcgaaac ggctgacgcc tgtgcagaga tgttcgcccg
    20581 caccaccgaa tccggcgttt attctcacgg cgttaatcgt ttccctcgtt tcattcaaca
    20641 actggaaaac ggcgatatca ttcctgatgc ccaacccaaa cgtataacca gcctcggcgc
    20701 aattgaacag tgggacgccc agcgttcgat cggtaacctg acagcgaaaa agatgatgga
    20761 tcgcgccatt gaactggctg ccgatcacgg tattggtctg gtggcactac gtaatgccaa
    20821 ccactggatg cgcggcggca gctacggctg gcaggcggcg gaaaaaggct atattggcat
    20881 ttgctggacc aactccatcg ccgtaatgcc gccgtggggc gcaaaagagt gtcgcatcgg
    20941 cactaacccg ctgatcgtcg ccattccttc cacgccgatc accatggtcg atatgtcgat
    21001 gtcgatgttc tcttacggca tgttagaagt taaccgtctg gcaggtcgtc agctcccggt
    21061 cgatggtggc tttgatgatg agggcaattt gaccaaagaa cctggcgtta tcgagaagaa
    21121 tcgccgcatt ttgccgatgg gctactggaa aggttctggc atgtcgattg tgctggatat
    21181 gatcgctact ctcctttccg acggcgcatc cgttgccgaa gtcacccagg acaacagcga
    21241 cgaatacggc atttcacaaa tttttattgc cattgaagtg gacaagctta tcgacggtcc
    21301 cacccgcgat gccaagctgc aacgcatcat ggattacgtt actagtgccg agcgtgctga
    21361 cgaaaatcag gccattcgct tacccggcca tgaatttact accctgctgg ccgaaaaccg
    21421 ccgtaacggc atcactgttg atgacagcgt gtgggccaaa atccaggcgt tatgaggaga
    21481 taagtcatga tttttggaca tatcgcgcag cccaatccgt gccgtttgcc cgccgccatt
    21541 gaaaaggcgc tcgattttct gcgcgctacc gatttcaacg ccctggagcc gggcgttgtc
    21601 gaaatcgacg gcaaaaatat ttatacgcaa attatcgatt taaccacacg cgaagcggtg
    21661 gtaaaccgtc cggaagtgca tcgtcggtat atcgatattc agtttctggc gtggggcgaa
    21721 gagaaaatcg gcattgctat tgatacggga aataataaag tcagcgaatc actattagag
    21781 cagcgcaata ttatttttta tcacgacagt gaacatgaat catttataga aatgataccg
    21841 ggcagctacg caattttctt tccgcaggat gttcaccgac caggttgtat tatgcaaaca
    21901 gcctctgaga tacgaaaaat tgtggttaaa gtcgcattaa cggcgctgaa ttaatcgaat
    21961 aatcgtctac gccagaacgc ctgggtaatg ttattgctct aactatatta ataattcagg
    22021 ttgctgcaca tgcgacttga attatgacag acatagcctc aaggaatagc tatgaaaaaa
    22081 atactcgaag caatactggc gattaatctc gccgtacttt cctgtattgt atttataaac
    22141 attattttaa gatatggttt tcagacaagc attttatctg ttgatgaatt gtcacgttat
    22201 ttatttgtct ggttaacgtt tattggcgcg attgtagctt ttatggataa cgcccacgtt
    22261 caggtcacct ttctggtgga gaaactctcc cccgcatggc agcgacgagt cgctctggtt
    22321 acccattcct taatcttatt tatttgtggc gcactggcct ggggcgcaac gctaaaaaca
    22381 attcaggact ggagcgatta ttcaccgatc ctcggtttac ccatcggcct gatgtatgcc
    22441 gcttgtctgc ccaccagcct cgttatcgca ttctttgaac tgcgtcattt atatcaactc
    22501 atcacgcgta gcaattctct aacgtcgcca ccgcaaggag cttaatcatg gctgtgctga
    22561 tttttctggg ctgtctgttg ggtggtattg ctatcggttt gcctattgcc tgggcactgt
    22621 tgttgtgcgg ggcggcgtta atgttctggc tggacatgtt tgatgtccag atcatggcac
    22681 aaacgctggt gaacggagcc gatagcttct ccctgctggc gattccgttc tttgtgctgg
    22741 cgggtgaaat catgaatgcg ggcggcttgt caaaacgcat tgttgacctg ccgatgaaac
    22801 tggtggggca taaaccaggc gggctgggct acgtcggcgt gctggcagct atgattatgg
    22861 cgagcctttc tggttctgcc gttgcggata ccgccgccgt tgccgctcta ctggtgccga
    22921 tgatgcgcag cgccaactat ccggtcaacc gggcggcggg gctgattgcc tctggcggca
    22981 ttatcgcgcc aattattccc ccttccattc cgtttattat cttcggcgtt tccagcggat
    23041 tatccatcag taagctgttt atggcgggca ttgcccctgg catgatgatg ggcgcaacgc
    23101 tgatgcttac ctggtggtgg caggccagtc gccttaattt accccgccag caaaaagcaa
    23161 cgatgcagga aatctggcac tcttttgtct ccggtatctg ggcgctgttt cttccagtca
    23221 tcattattgg cgggtttcgc tccggtctgt ttacccctac cgaagccggg gccgttgctg
    23281 ctttctatgc gctgtttgtc gccacagtta tttaccgtga aatgaccttc gccacacttt
    23341 ggcatgtact cattggcgcg gcgaaaacca cctcagtggt tatgtttctg gtggcctcgg
    23401 cacaagtttc cgcctggctg attaccattg ctgaactgcc gatgatggtt tctgatttac
    23461 tgcaaccgtt ggtcgattca ccgcgtctgc tgtttatcgt cattatggtg gctatcctga
    23521 ttgtcggcat ggtcatggat ttaacgccga cggtattaat tcttaccccg gtattaatgc
    23581 ctttagttaa agaggcagga atcgatccga tttatttcgg tgtcatgttt atcattaact
    23641 gctcaatcgg cttaattaca ccgcctatcg gtaatgtact taacgttatt tcaggggtgg
    23701 caaaactcaa attcgatgat gcagtcagag gcgttttccc ttacgtcctg gttttatatt
    23761 cattattagt cgtatttgtt tttattcccg atctcatcat cctccctttg aaatggatta
    23821 attaaaagga aaatattatg aaattacgct ctgtaaccta cgcattattc attgctggcc
    23881 tggctgcatt cagcacatct tctctggcgg cacaatcttt acgtttcggt tatgaaacat
    23941 cacaaaccga ctcgcaacat attgcggcga aaaaattcaa tgatttattg caggagagaa
    24001 ccaaaggcga gctgaaatta aaactgttcc cggacagcac tctcggtaac gcgcaggcga
    24061 tgatcagcgg cgtacgtggc ggcaccatcg atatggaaat gtccggctcg aataactttg
    24121 ccgggttatc accagtgatg aacttgcttg atgtcccttt cctgttccgc gataccgctc
    24181 acgcgcataa aacgctcg
//
LOCUS       DACAOP010000068        24065 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.068, whole genome shotgun sequence.
ACCESSION   DACAOP010000068 DACAOP010000000
VERSION     DACAOP010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24065
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.068"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     repeat_region   185..762
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=246..274
                     /rpt_unit_seq="cggtttatccccgctggcgcggggaactc"
     gene            complement(1101..1772)
                     /gene="queE"
                     /locus_tag="IT892_002984"
     CDS             complement(1101..1772)
                     /gene="queE"
                     /locus_tag="IT892_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HAP3136176.1"
                     /translation="MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTW
                     EKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLL
                     PLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKH
                     PVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHK
                     YLNIA"
     gene            1911..2052
                     /locus_tag="IT892_002985"
                     /pseudo
     CDS             1911..2052
                     /locus_tag="IT892_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791252.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2066..2938
                     /locus_tag="IT892_002986"
     CDS             2066..2938
                     /locus_tag="IT892_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417258.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgcG family protein"
                     /protein_id="HAP3136177.1"
                     /translation="MRYFILIFTFVCSFIAAQPTIVPSLQQQVTDLMSSLNSQEKKEL
                     TYKLESIFNNTQVQIAVLIVPTTKDETIEKYATRVFDNWRLGDAKRNDGILIIVAWSD
                     RTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAQGLELAINALNNQLTSQHQY
                     PANPSEIESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSSVCISAIYLLDL
                     FLFSDKTFSIAVFFFFFTFTTIMVFTCLCVLQKRASGRSYHSDNSGSAGGSDSGGFSD
                     GGGSSGGGGASGRW"
     gene            complement(2998..4296)
                     /gene="eno"
                     /locus_tag="IT892_002987"
     CDS             complement(2998..4296)
                     /gene="eno"
                     /locus_tag="IT892_002987"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAP3136178.1"
                     /translation="MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
                     SREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEN
                     KSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHA
                     DNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGS
                     NAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHF
                     LEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKG
                     IANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQI
                     KTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA"
     gene            complement(4383..6020)
                     /gene="pyrG"
                     /locus_tag="IT892_002988"
     CDS             complement(4383..6020)
                     /gene="pyrG"
                     /locus_tag="IT892_002988"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase (glutamine hydrolyzing)"
                     /protein_id="HAP3136179.1"
                     /translation="MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPY
                     INVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRK
                     ERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQM
                     AVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPA
                     NERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEW
                     EQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVE
                     TRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARH
                     VANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVD
                     DSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPW
                     FVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK"
     gene            complement(6248..7039)
                     /gene="mazG"
                     /locus_tag="IT892_002989"
     CDS             complement(6248..7039)
                     /gene="mazG"
                     /locus_tag="IT892_002989"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HAP3136180.1"
                     /translation="MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVL
                     DAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFAD
                     SSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWT
                     TLGPVVDKVYEEIDEVMYEARQAVIDQAKLEEEMGDLLFATVNLARHLGTKAEIALQK
                     ANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL"
     gene            complement(7111..7446)
                     /gene="mazF"
                     /locus_tag="IT892_002990"
     CDS             complement(7111..7446)
                     /gene="mazF"
                     /locus_tag="IT892_002990"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease MazF"
                     /protein_id="HAP3136181.1"
                     /translation="MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTG
                     MCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLI
                     KAKINVLIG"
     gene            complement(7446..7694)
                     /gene="mazE"
                     /locus_tag="IT892_002991"
     CDS             complement(7446..7694)
                     /gene="mazE"
                     /locus_tag="IT892_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin MazE"
                     /protein_id="HAP3136182.1"
                     /translation="MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLII
                     EPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW"
     gene            complement(7772..10006)
                     /gene="relA"
                     /locus_tag="IT892_002992"
     CDS             complement(7772..10006)
                     /gene="relA"
                     /locus_tag="IT892_002992"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP diphosphokinase"
                     /protein_id="HAP3136183.1"
                     /translation="MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQ
                     QTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRECVGKS
                     VVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHL
                     REVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLL
                     HERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDV
                     RAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTV
                     EIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGE
                     MLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVP
                     FTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAG
                     RQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNK
                     PSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGF
                     ITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVMANDRSGLLRD
                     ITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR
                     LHGS"
     gene            complement(10054..11355)
                     /gene="rlmD"
                     /locus_tag="IT892_002993"
     CDS             complement(10054..11355)
                     /gene="rlmD"
                     /locus_tag="IT892_002993"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP3136184.1"
                     /translation="MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKALFIPGL
                     LPQENAEVTVTEDKKQYARAKVVRRLSDNPERETPRCPHFGVCGGCQQQHASVDLQQR
                     SKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVK
                     QCPILVPQLEALLPKVRACLDSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREK
                     LERFSHSEGLDLYLAPDSEILETVAGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVA
                     RALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLH
                     NVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPA
                     TLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK"
     gene            11412..14168
                     /gene="barA"
                     /locus_tag="IT892_002994"
     CDS             11412..14168
                     /gene="barA"
                     /locus_tag="IT892_002994"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase BarA"
                     /protein_id="HAP3136185.1"
                     /translation="MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDA
                     GASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFH
                     LDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYI
                     ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRR
                     GQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQN
                     VELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTI
                     ERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTL
                     NIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIR
                     DTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNR
                     GSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYS
                     PTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKL
                     KQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKL
                     IGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQ
                     QTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPE
                     VNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGL
                     VDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREAS
                     KILG"
     gene            complement(14399..15739)
                     /gene="gudD"
                     /locus_tag="IT892_002995"
     CDS             complement(14399..15739)
                     /gene="gudD"
                     /locus_tag="IT892_002995"
                     /EC_number="4.2.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HAP3136186.1"
                     /translation="MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIK
                     DNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVLTLVRNTFADRDAGGRGLQ
                     TFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKAT
                     PLPYQSQPDDKCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAE
                     SIVALAQRFPQARITLDPNGAWSLNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMA
                     EFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGL
                     TWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGLVQV
                     PQKPGLGVEIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR"
     gene            complement(15760..17100)
                     /locus_tag="IT892_002996"
     CDS             complement(15760..17100)
                     /locus_tag="IT892_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase-related protein"
                     /protein_id="HAP3136187.1"
                     /translation="MTTQSSPVITDMKVIPVAGHDSMLLNIGGAHNAYFTRNIVVLTD
                     NAGHSGIGEAPGGEVIYQTLVDAIPMVLGQEIARLNKVVQQVHKGNQAADFDTFGKGA
                     WTFELRVNAVAALEAALLDLLGKALNVPVCELLGPGKQRDAITVLGYLFYIGDRTKTD
                     LPYLENTPGNHEWYQLRHQKAMNSEAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDT
                     VRALKKRFPDARITVDPNGAWLLDEAISLCKGLNDVLTYAEDPCGAEQGFSGREVMAE
                     FRRATGLPVATNMIATNWREMGHAVMLNAVDIPLADPHFWTLSGAVRVSQLCDDWGLT
                     WGCHSNNHFDISLAMFTHVGAAAPGNPTAIDTHWIWQEGDCRLTKNPLEIKNGKIAVP
                     DAPGLGVELDWEQVQKAHEAYKRLPGGARNDAGPMQYLIPGWTFDRKRPVFGRH"
     gene            complement(17102..18454)
                     /locus_tag="IT892_002997"
     CDS             complement(17102..18454)
                     /locus_tag="IT892_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136188.1"
                     /translation="MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGS
                     EMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQ
                     GFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
                     FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYI
                     AAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFP
                     VYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGM
                     LLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMF
                     GNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ
                     "
     gene            complement(18889..19338)
                     /locus_tag="IT892_002998"
     CDS             complement(18889..19338)
                     /locus_tag="IT892_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAP3136189.1"
                     /translation="MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHKATVFEDPELSDW
                     LPYQDKYVLVVTSTTGQGDLPDSIVPLFQGIKDSLGFQPNLRYGVIALGDSSYVNFCN
                     GGKQFDALLQEQSAQRVGEMLLIDASENPEPETESNPWVEHWGTLLS"
     gene            complement(19356..20138)
                     /gene="truC"
                     /locus_tag="IT892_002999"
     CDS             complement(19356..20138)
                     /gene="truC"
                     /locus_tag="IT892_002999"
                     /EC_number="5.4.99.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(65) synthase TruC"
                     /protein_id="HAP3136190.1"
                     /translation="MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIG
                     QHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDY
                     PLVEELDKIADKFAREDKGPQPAVTHYRGLATVEMPIATGRYPTTRYGLVELEPKTGR
                     KHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLT
                     IHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGEISS"
     gene            complement(20138..20467)
                     /locus_tag="IT892_003000"
     CDS             complement(20138..20467)
                     /locus_tag="IT892_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqcC family protein"
                     /protein_id="HAP3136191.1"
                     /translation="MTTHDRVRLQLQALEALLREHQHWQNDEPQPHQFNSTQPFFMDT
                     MEPLEWLQWVLIPRMHDLLDNNQPLPGAFAVAPYYEMALATDHPQRALILAELEKLDA
                     LFADDAS"
     gene            complement(21089..21634)
                     /gene="syd"
                     /locus_tag="IT892_003001"
     CDS             complement(21089..21634)
                     /gene="syd"
                     /locus_tag="IT892_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SecY-interacting protein"
                     /protein_id="HAP3136192.1"
                     /translation="MDDLTAQALKDFTACYCDAWHEEHKSWPLSEELYGVPSPCIIST
                     TEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQ
                     TWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGT
                     RKRTHLASNLAEFLNQLKPLL"
     gene            21702..22550
                     /gene="queF"
                     /locus_tag="IT892_003002"
     CDS             21702..22550
                     /gene="queF"
                     /locus_tag="IT892_003002"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HAP3136193.1"
                     /translation="MSSYANHQALAGLTLGKSTDYRDTYDASLLQGVPRSLNRDPLGL
                     KADNLPFHGTDIWTLYELSWLNAKGLPQVAVGHVELDYTSANLIESKSFKLYLNSFNQ
                     TRFNNWDEVRQTLERDLSTCAQGKVSVALYRLDELEGQPIGHFNGTCIDDQDITIDNY
                     EFTTDYLENATSGEKVVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRQIDREKLLRY
                     LVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPWRSNSDFVPST
                     TRLVRQ"
     gene            22662..24026
                     /gene="ppnN"
                     /locus_tag="IT892_003003"
     CDS             22662..24026
                     /gene="ppnN"
                     /locus_tag="IT892_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide 5'-monophosphate nucleosidase"
                     /protein_id="HAP3136194.1"
                     /translation="MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNS
                     GSLTDNSKELLSRFENFDINVLRRERGVKLELINPPEEAFVDGRIIRALQANLFAVLR
                     DILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
                     ENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPS
                     IIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPA
                     NKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIIDDAAEVARQMKKSMP
                     LVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLYPDQPVEVLAADLRRAF
                     SGIVAGNVKEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCY
                     EICT"
BASE COUNT         5942 a         6349 c         5706 g         6068 t
ORIGIN      
        1 aaatttctta acggtttaag gattatacaa ataacacttt gattaaattt gattttttgt
       61 atcgataatt gtgaacttct catatatgga gagctatttt gaacatgagg tgttacgtgg
      121 atatgttgct taatacgagt actgctaata taaaaacttg agaaagagat aacgggttat
      181 atggtggttt attcccgctg gtgcggggaa ctcatcagtg atatccaaca ttgcggagct
      241 aaacgcggtt tatccccgct ggcgcgggga actcacgaac gcggcacacc agggcgtctc
      301 atcgtccggt ttatccccgc tggcgcgggg aactcggcac atgcctgatc atatgtgtag
      361 caacggtcgg tttatccccg ctggcgcggg gaactcacga tgtatgaccg gaaaacctca
      421 gactggcgcg gtttatcccc gctggcgcgg ggaactcgcc gcgttatttt ccctgaaaac
      481 aataaagctc ggtttatccc cgctggcgcg gggaactcta atatccctgg cgataatcaa
      541 ccggcttact cggtttatcc ccgctggcgc ggggaactcg agagcgaggg gagattccgg
      601 cagggcgtgc acggtttatc cccgctggcg cggggaactc gcgggtatgc tccgctccgt
      661 gttcgacaaa ctcggtttat ccccgctggc gcggggaact caaggtcgcg gggacgccac
      721 gggcagtcaa tgtcggttta tccccgctgg cgcggggaac tcactaaaca taacctatta
      781 ttaattattg attttttaag tcagtcacaa tctaccaact taacagaaac acacaaacaa
      841 cacatccatt atgttaaaga gcacttaatt cattgattga aaagccaaat atttaaagta
      901 attctatacc gactaaaatc caccaaactc cgacgtaata attttcactc caacgaaaaa
      961 ttaacgccac agaatttgta gaaaatgata atgattagtc caggatgggc aaaatggagg
     1021 ttttttagag gcgacaaaga atataaatga gtagaagtct ttacaggttc cacccattta
     1081 taacgcttat aaatgtgtaa tcaggcaata tttaaatatt tatgtgtttg catcgacaaa
     1141 cgccaattac gcgcaatgca ggtttcaatg cacaaacgtg tggcatcatc cttttggcta
     1201 atcggctgca gtgcaatgac tcgcggttta tcatcggtca gcgtcgcaag caattcatcc
     1261 agtgcttcga tatcacgtac gcgtccaact gggtgtttga tttcgttagc tcgctccagg
     1321 gcttgcgaca atacttcata accaccacgc atatttagct ttggcgacac ggtgacccag
     1381 gtattcggcg tacaacgcac ttcatgagta ccgctggttt ctatctggca gctaaaaccg
     1441 ttcttttcga gcaggtcagt cagtggcagc aaatcatgaa tgcaaggctc accacccgta
     1501 atcaccacat gccgcgcggt gtatccctgg cgaccaatga cagccagcaa gtcttcactg
     1561 ctcgccgccc cccacttatc actctctttg gtcttcgcca gaatgctgaa aagggagact
     1621 tcccgatcct caagcttttc ccaggtgtgt ttggtgtcgc accaggcaca gccaaccggg
     1681 catccctgta aacgaataaa aatggcgggg acgccggtaa agtaaccctc accttgcagg
     1741 gtctggaaca tctcgttaat cgggtactgc atagcattct ctgtgaagtg gataattgtt
     1801 aattattgca gatcctgcca caacaatcat gtcttattaa cattctgtta caggcaggtt
     1861 taaagaaaaa tgagaaacag atcgttaata ataaaaggga gtaacgtatt atgtcagaaa
     1921 taaataaagt aaagggattt aatcatgtca aaaacattca ccaaaattat acttattttt
     1981 tctgtgttcg tttttaatta taacgaatct caaattaccg atgccgccgt caatttattt
     2041 atccagcttt aatgggacat ttataatgcg ctatttcata ctaatattca cattcgtgtg
     2101 ttcctttatt gcagcccaac caactattgt cccatcatta cagcaacaag ttacggatct
     2161 tatgagtagc ttaaactcac aagaaaagaa agaactgacg tacaagttag aatctatttt
     2221 caataatacc caagtgcaaa ttgctgtatt aattgttccc acaaccaaag acgagacaat
     2281 tgaaaaatat gctacacggg tttttgacaa ttggcgttta ggagatgcca aacgtaatga
     2341 tgggatactg atcattgttg cctggtcgga tcgtactgtc cgcatccagg taggttatgg
     2401 gctggaagaa aaggtaaccg atgctctggc tggagatatc atccgtagca acatgatacc
     2461 cgcatttaaa caacaaaaat tagctcaggg attagagcta gctataaacg ctttgaataa
     2521 ccaactcact tcacaacacc aatatccggc taatccttca gaaattgaat cagcgtcttc
     2581 cagtgatcat tattactttg ctattttttg ggtatttgca gtgatgttct tccctttctg
     2641 gttttttcat caaggcagta atttttgtcg cgcatgtaaa agcagtgtct gtatttcagc
     2701 aatctatctt ttagatttat tcctgttctc cgataaaact ttttccattg ctgtattttt
     2761 cttctttttt actttcacca ccattatggt ctttacctgt ttatgtgtac ttcagaaaag
     2821 agcatctggt agaagttatc attcagacaa cagcggttcc gctggaggct cagatagcgg
     2881 cggcttcagc gatggtggcg gttcttctgg cggtggcggc gcatccggtc gctggtaact
     2941 ccaccataaa aaatgccagc ccgaaggctg gcattatcaa atcagataaa gtcagactta
     3001 tgcctggcct ttgatctctt tacgaccgtt gtacggtgct ttttcgccca gagcttcttc
     3061 gatacgaatc agctggttgt atttagcaac acggtcagaa cggctcatag aaccagtttt
     3121 gatctggcct gcagcagtac caacagccag gtcagcgatg gtagcatctt cagtttcgcc
     3181 agaacggtga gagataactg cagtgtagcc agcatctttc gccatcttga ttgcagccag
     3241 agtttcggtc agagaaccga tctggttgaa tttgatcagg atggagttag cgataccttt
     3301 ttcgatacct tctttcagga tcttggtgtt ggttacgaac aggtcgtcac caaccagctg
     3361 gattttgtcg cccagaactt tggtctggta tgcgaaaccg tcccagtcag attcgtccag
     3421 accgtcttcg atagatacga tcggatactg tttggtcagt tcttccagga agtgagtgaa
     3481 ttcttcagag gtgaatgctt tgttgccttc gccagccaga acgtatttac cgtctttgta
     3541 gaattcagaa gctgcgcagt ccatcgccag agtgatgtct ttgcccagtt cataaccagc
     3601 agctttaaca gcttcagcga taacagccag agcttcagcg ttggaaccca ggttcggcgc
     3661 atagccacct tcgtcaccaa cagcagtgtt catgcctttc gctttcagaa cttttgccag
     3721 gtgatggaaa acttcagaac ccatgcggat ggcttctttc acagttttcg cgccaaccgg
     3781 ctgaatcatg aattcctgga tatcaacgtt gttgtcagcg tgctcaccac cgttgatgat
     3841 gttcatcatc ggaaccggca tggagtattt gcccggagtg ccgttcagtt cagcgatgtg
     3901 ctcgtacagc ggcatgcctt tagcggcagc agcagctttg gcgttagcca gagatacagc
     3961 caggattgcg ttcgcgccga atttggattt gttttcggtg ccgtccaggt cgatcatgat
     4021 cttgtcaatg ccagcctgat ctttggcatc tttgccaatc agtgcctgag cgatcgggcc
     4081 gtttaccgca gcaacagctt tggttacgcc tttacccagg aaacgggatt tgtcgccatc
     4141 gcgcagttcc agagcttcac gggaaccagt agaagcacct gacggagcag ctgccatacc
     4201 gacgaaacca ccctccagat gtacttcggc ttcaacagtc gggttaccac gggagtcgat
     4261 gatttcacga ccgatgattt ttacgatttt ggacattagg ttttcctcaa gtcactagtt
     4321 aaactgaaac tccagacaaa caacgcgtac ccagggtacg cgttgccgtt ctaacttttt
     4381 tcttacttcg cctgacgctt ctggaactcg ctggcggctt tcacaaagcc tgcaaacagc
     4441 gggtgaccat cacgtggagt agaagtaaac tccggatgga actggcaagc cacgaaccac
     4501 gggtgattcg gaacttcgat gatctcgacc aactgatcat ccccggaacg gcccgcaacg
     4561 cgcagacctg catcttcaat ctgtttcaac agcatgttgt tgacttcgta acggtgacga
     4621 tgacgctcaa caattgtcgg cgcattgtac agctggcgaa ccaagctatc gtcaaccaac
     4681 tggcactgct gtgcgccgag acgcatggta ccgccgagat cgctcttctc gctacgaact
     4741 tcaacgttgc cgttttcatc gcgccactcg gtaatcagcg ccacaaccgg gtacttacag
     4801 tctggcacaa attccgtaga gttggcgttc tccatgttgg caacatggcg agcgtaatca
     4861 attaacgcca cctgcatacc caggcaaatg cccagataag gaatattgtt ctcacgcgca
     4921 aaacgcgcgg tcgtaatcat gccttctacg ccacgatagc cgaaaccgcc aggtacgagg
     4981 attgcgtcca gacctttaag aatttcaacg ccgcgcgttt caacatcttg tgaatcgatc
     5041 agtttgatgt tgacgctgac acgattcttc agcccaccgt gtttcagtgc ttcgatcacg
     5101 gatttgtaag cgtccggcag ttcaatgtac ttgccgacca taccaatggt gacttcactt
     5161 accggattcg cttcttcgaa gataacctgt tcccattcgg acagattcgc ttccgggcag
     5221 tttaagctga atcgtttaca aatataatcg tccagcccct gcgatttcaa caggcccgga
     5281 attttataga tggaatcgac gtctttcaga gaaataaccg ctttttccgg aacattacag
     5341 aacaatgcaa tcttcgcacg ttcgttcgcc ggaacggcgc gatctgaacg acaaatcagg
     5401 atgtcaggct ggataccgat ggagagcagc tcttttacag agtgctgagt cggtttggtt
     5461 ttgacttcac cagacgctgc catgtacggc accagcgtca ggtgcataaa cagggtgtgc
     5521 tcacggccaa tttcaacagc catctggcga atcgcttcga ggaacggcag ggattcgata
     5581 tcacctactg taccgccgat ttcgaccagt accacgtcat gaccttcgcc gccttccagc
     5641 acgcgctctt tgatagcgtt agtgatgtgc ggaataacct gtacggttgc gccgaggtag
     5701 tcaccgcggc gttctttacg cagaacgtca gagtagatac gacccgtggt gaagttgttg
     5761 cggcggctca ttttggtacg aatgaaacgc tcgtagtgcc ccaggtccag gtcggtttca
     5821 gcgccgtctt cggtaacgaa cacttccccg tgttggattg ggctcatagt acctggatcg
     5881 acgttgatgt acggatccag tttcatgatg gtcacattga ggccacgggc ttcaagaatg
     5941 gctgcgaggg aggctgcggc aatgccttta cccagagagg atacgacccc gccggtcaca
     6001 aaaatatagt tcgttgtcat gctgaacctg agaagttagg ttgaaaagac gatggaataa
     6061 ccaggacggg aaagcagtat acccgaacat gacctatgcc acaaactttc attatccctc
     6121 ctcttcgcca gcgcactatt gaaatcagga gtgagaaaat agcccctttg gggtaaatgt
     6181 ttttgacgca aatcaagcgc ttgtcattta aaaaatgaca caaatcgcgc ttgaccacgt
     6241 aattccctta gagatcaatt tcctgccgtt ttacctgttg ccagacttct tccattgttt
     6301 cgaggtcaac acctgtcatt tccagtccac gcgcggcaac aatacgctcc acttcgcgaa
     6361 aacgacgctc gaatttttcg ttcgcttttt gcaatgcgat ttccgctttt gtccctaaat
     6421 gacgagccag attgaccgtg gcaaacagca ggtcgcccat ttcctcctcc agtttagcct
     6481 ggtcgataac agcctgccgt gcctcgtaca tcacctcgtc gatctcttcg tagactttat
     6541 cgactaccgg accaagcgtc gtccagtcaa aaccaacgtt ggcgcaacgt ttctggattt
     6601 tttgcgcacg cattaaagcc ggtaaactac gaggaatatc gtccagcgcc gaatgctgcg
     6661 ctttctgcgc gcgctcttcg gttttgattt gctcccaacg ggcaagcact tcactactgt
     6721 tttcggcaga actgtcagca aaaacatgcg gatggcgacg ttctaattta tcgctgatcg
     6781 cggcgcatat atcattaaag tcaaagcgcc cttcttcctg agccatttgt gcgtaaaaca
     6841 ccacctggaa cagcagatcg cccagttcac cgcgaagatc gtcaaaatct tcacgggcga
     6901 tggcgtccag cacctcgtag gtttcttcaa gggtgtaagg cgcaatggtg gcaaatgtct
     6961 gctctttatc ccacgggcag ccgttttccg gatcgcgcag gcgctgcatg atggtgagca
     7021 aacggtcgat ttgattcatt agaatgtcct gaaaattgcg ggtccgtcag gtggaaacct
     7081 gtgaccagaa tagaagtgag ttagtaacac ctacccaatc agcacgttaa ttttggcttt
     7141 aatgagctgt aattcctctg gggcaaccgt tcctttcttc gttgctcctc ttgcccgcca
     7201 ggcgatactt tttacctgat cagctaacgc tacgccatca cgttcctgac cggataaaac
     7261 aacttcgaac ggatatcctt ttgattgcgt tgtacaagga acacacagac acatacctgt
     7321 tttgttgttg tacatgaacg gactcaggac aacagccgga cgatgtccgg cttgctcgct
     7381 accttttgtc gggtcaaaat caacccaaat cagatcgccc atatcgggta cgtatcggct
     7441 taccattacc agacttcctt atctttcggc tctccccagt cgatattctc gtggaggttt
     7501 tccggcgtga tgtcgttgac cagttcagca agcgtaaata cgggctcttt acgcactggc
     7561 tcaataatta atttgccatc caccaggtca atcttcactt catcatcaat attcagattg
     7621 agcgcctgca ttaacgtagc cgggatccgc accgccggtg aatttcccca acgctttacg
     7681 ctactgtgga tcataaccct ttcctcaaac cgctatcata tgtagataca gtatatatca
     7741 atctacattg tagatacgag ctaatttcgg cctaactccc gtgcaaccga cgcgcgtcga
     7801 taacgtctgg cacctgattg agtttaccca gcacgcggcc cagcacttgc agattgtaaa
     7861 tctcaatggt catgtcgata gtcgccagtt gctgtttagt gtcgctacgg ctggcaacgc
     7921 caagcacgtt caccttctcg ttggcaagaa tggtcgtgat atcacgcaat aatccactgc
     7981 gatcattggc catcacccgg accaccagcg aatatccggc ggagtagctc tcaccccata
     8041 ccgcgtcaac aatgcgttct ggcgcatggg agcgcagttc cgccagttgt tcgcaatcgg
     8101 cgcggtgtac tgaaataccg cgtccctggg taatgaagcc gacaatctca tctccaggaa
     8161 tcggctgaca gcagcgcgcg atgtggtgca tcaggttgcc gacaccttct accaccacac
     8221 gaccgttatc tttactgcgg ttttgcggcg tatagctttt ttgctgaagt tgcttcagcg
     8281 cggcggcatc ctgctcttcg gcactcggct tattaaattg cgattgcagg aagttcacca
     8341 tctgattgag acggatatcc ccgccaccaa ttgccgccag caactcgtcg acatcattga
     8401 agttgtaacg cggcagcaga tgtttttctg cttctttcag gctgatcccc agatgttcca
     8461 gctcgtcgtc aaggatttgc cgcccagcca gaatgttttt gtcacggtcc tgtttacgga
     8521 accaggcgtg aattttcgaa cgcccacggc tggttgtgac gtaaccgagg tttgggttta
     8581 accagtcacg gctggggttc ggctgtttct gggtgataat ttcaatctgg tcgcccatct
     8641 gcagctggta ggtgaacggc acaatgcgcc cgccaatttt tgccccgatg cagcggtgtc
     8701 cgacatcact gtggatgtgg taagcgaagt ccagcggtgt tgatcccgca ggcaaatcaa
     8761 cgacgtcacc tttcggcgta aagacgtaca cccggtcgtc aaagacctgg ctgcgtactt
     8821 cgtcgagcat ttcgccggaa tcagccatct cttcctgcca cgcaatcagt ttacgcagcc
     8881 aggcaattcg gtcttcatgt cccgaacgtg cgccgccagc tgccgcgcct tctttatatt
     8941 tccagtgcgc agcaacaccc aactctgcat cttcatgcat ctgtttggtg cggatttgga
     9001 tctctacggt tttgccacct ggtcccagaa ccacggtatg aatagactga taaccgtttg
     9061 gtttcgggtt agcgacgtaa tcgtcaaact catccggcag gtggcgatag tgagtgtgca
     9121 ctatccccag tgcggcataa caatcctgta aacgctcggc gacaatacgt accgcacgca
     9181 catcaaacag ctcatcgaag gcgaggttct ttttctgcat tttgcgccag atgctgtaga
     9241 tgtgtttcgg acgaccatac acttcagctt taacgccttc agctttcatc tcagcgcgca
     9301 gatgaccgac aaactcttcg atatagtgtt cgcggtcgag acggcgttca tgcaacagtt
     9361 ttgcgatgcg tttgtattcg gtcgggtgga gataacggaa gcagtaatct tccagctccc
     9421 atttcagttg tccaatccca agacggttcg ccaacggcgc gtagatattg gtgcactctt
     9481 ttgccgccag tacgcgttca tcttccggcg cgtcttttac ttcgcgcaga tgagcaatac
     9541 gctctgccag tttaatgacc acgcagcgaa aatcatcgac catcgccaat aacatccggc
     9601 gaacgttatc gacctgttcg gaggaaacag aatcggtatg cgtcgctttc agctggcgga
     9661 tcgccgccat atcacgcacg ccgtgaataa ggttaacgac cgacttaccg acgcactcac
     9721 gcagcacatc ttcgctgact acgttggcat ccgccagagg gaacagcagc gccgcccgca
     9781 gcgtgtcaat gtccatactt aatgtcgaga ggatctccac catctcaaca ccacgccaca
     9841 ataacagact ggcatccgga tgtccctgcg tctgttgcag acaatacgcc caggtttcgg
     9901 ctaagcactc acacgacttc tggctggtaa tacccagact tgcgatccat ttttccggat
     9961 caaattcacc agccttattg atatgtgcac ttcttaccgc aaccatcgtc ctctccttta
    10021 gggaccagac ctgccgaaat cggcaaatcg taactattta acgcgcgaga aaagtaccat
    10081 cgattccaga tgtcccgtgt gtgggaacat atccagcatc gccagtcgcg caatggtata
    10141 tcctgctttt aataacgctt cgctatcccg agccagcgtt gcagggttac aggatacata
    10201 aactatacga ataggttcca gttttataat ttgctgcata acacctgcgg cacctgctcg
    10261 cgccgggtcc agcaacactt tatcgaagcc gtttttcgcc cacggctgct ttgtgacatc
    10321 ttcttcaaga ttttcgtgat aaaacgtcac attgtgtaag ccattaagac gcgcattctg
    10381 ctggcctttt tccaccagcg ccggaacgcc ttctacaccc accacactgg cagcttgtgt
    10441 cgccaatggc agtgtaaagt tgcccatacc gcagaacaga tccagtacgc gatcttcagg
    10501 ttgcacatcc agccattcca acgcacgcgc taccattttt tggttcacac ccgcattgac
    10561 ctgaataaaa tcgcgcgggc taaaagttaa gcgcaacccg tttgagtcat accagggcat
    10621 ctcaccagcg acggtttcga gtatctcact atcgggggcg agatacagat ccaggccttc
    10681 agaatgcgaa aagcgttcca gtttttcgcg atcagccgaa cttagcggtg cggtatggcg
    10741 caaaatcatc agcgtgccgc tggttgcctg taccagttca acatgaccaa gatggcgcat
    10801 agcttgtaag ctgtccaggc atgccctgac tttgggcagc aatgcttcaa gttggggcac
    10861 taaaatgggg cattgtttaa cgtcgacaat gtcactggag cccgctttgc gaaaccccat
    10921 ctgaagttgc tgtgttttcg gtaagtagtt caaacttaaa cgcgcgcgac ggcgatagcc
    10981 ccagggaaca tcggcgatca cttcagagac ttcgtgtttc attaatcggg cgagtgccgc
    11041 acttttgctt cgctgctgta aatccacgct ggcgtgttgt tgctgacagc cgccgcatac
    11101 gccaaaatga gggcagcgtg gcgtttcgcg ttccgggtta tcgcttaacc ggcgcacgac
    11161 tttagcgcga gcgtactgtt ttttatcttc agtaacagta acttccgcgt tttcctgtgg
    11221 cagtaatcca ggaataaata acgctttgcc gttatgtcgc gccacgccct gaccaaaaga
    11281 gtcgaggtcg ttgactgaaa cagttatgat ctgacgcgtc gtcgtgcgtc gttttgcaga
    11341 gtagaattgc gccattggcg agactttctc aatttaacag tgtgacctta attgtcccat
    11401 aacggaactc catgaccaac tacagcctgc gcgcacgcat gatgattctg atcctggcac
    11461 cgaccgtcct tattggttta ttgctgagta tctttttcgt tgtgcatcgc tataacgact
    11521 tgcagcgtca actggaagat gccggagcca gcattattga gccgcttgca gtttctactg
    11581 aatatggcat gagcctgcaa aatcgcgaat ctatcggtca gttaataagc gtactgcatc
    11641 gtcgccattc cgatattgtt cgcgcgattt cggtttatga tgaaaataac cgactctttg
    11701 tcacctccaa ttttcatctt gatccttcat caatgcagct cggcagcaac gtgccgtttc
    11761 ctcgccagct cactgtcact cgtgacggcg atattatgat cctccgcacg ccgattattt
    11821 ctgagagtta ctcccccgac gaatcgccca gtagcgatgc caaaaatagt caaaatatgc
    11881 tgggatatat tgcgctggag ctggatctta aatcggttcg cttgcagcaa tataaagaga
    11941 tctttatttc cagcgtgatg atgctgtttt gtatcggtat tgcgcttatt tttggctggc
    12001 gcttaatgcg cgatgtaacc ggtccgattc gcaacatggt gaataccgtc gaccgcatcc
    12061 gtcgcgggca actcgacagc cgggtggaag gatttatgct cggcgagctg gatatgctga
    12121 aaaacggtat caactcgatg gcaatgtcgc tggctgctta tcacgaagag atgcagcata
    12181 atatcgacca ggcgacgtcc gatctgcgtg aaacgctgga gcagatggaa attcagaacg
    12241 ttgagttgga tctggcgaaa aagcgcgccc aggaagcggc gcgtattaaa tccgagtttc
    12301 tggcaaatat gtcacacgag ctgcgtacac cactgaatgg tgttattggc tttacccgcc
    12361 tgacgctgaa aacagaatta acaccaacgc agcgcgatca cctgaatacg attgaacgtt
    12421 cggcaaataa tttgctggca attattaatg atgttctcga cttctcgaaa ctggaagcag
    12481 gtaagctgat tctggaaagt attccattcc cactacgcag cacgctggat gaagtcgtta
    12541 ccctgctggc acattcttct cacgataaag ggttggaact gacgctcaat attaagagcg
    12601 acgtgcccga taacgtgatc ggcgacccac tgcgattaca gcaaatcatc actaacctgg
    12661 tggggaatgc aattaaattc accgagaatg gcaacattga tattctggta gaaaaacgtg
    12721 cgctgagtaa taccaaagtg cagattgaag tgcagattcg ggataccggc attggtattc
    12781 ctgaacgcga tcaatcgcgc ttattccagg ccttccgaca ggctgatgcc agtatttccc
    12841 gccgtcatgg tggtaccggg ctggggctgg tgattacaca aaaactggtt aatgaaatgg
    12901 gcggcgatat ttcgttccat agccagccga atcgcggttc aactttctgg ttccacatta
    12961 atctcgatct gaatccgaac attattatcg aagggccatc cacccagtgc ctcgccggca
    13021 agcgcctggc ctatgtcgaa ccaaactccg cagcagcgca atgcacgctg gatattttaa
    13081 gtgaaacgcc gctggaagtg gtttatagcc caacgttctc cgcgctgcct cccgcgcatt
    13141 acgacatgat gttgttaggc atcgcggtga ccttccgcga gccgctaaca atgcaacatg
    13201 agcgattagc gaaagcagta tcgatgaccg attttctcat gctggcactt ccttgccatg
    13261 cacaagtcaa tgctgaaaaa cttaagcaag atggtatcgg cgcgtgtctg ctgaaaccat
    13321 taacacctac gcgcctgtta cctgccctga cggaattttg tcatcacaaa caaaacacgc
    13381 ttttgcctgt aaccgatgaa agtaagctgg caatgacagt catggcggtt gatgacaacc
    13441 ccgctaacct gaaacttatc ggcgcattgc tggaagatat ggtgcaacat gtggaacttt
    13501 gcgatagcgg gcatcaggcg gttgaacggg cgaaacagat gccgttcgat ttgatcttaa
    13561 tggatattca aatgccggac atggacggta ttcgggcctg cgaactcatc caccagctcc
    13621 cccatcagca acaaacgccg gttatcgcgg taacggcgca tgcaatggcc gggcaaaaag
    13681 agaagctgct tggcgcaggg atgagcgatt atctggcgaa accgattgaa gaagaacgat
    13741 tgcataattt gctgttgcgc tacaagcctg gcagcggtat ttcctctcgc gtcgtgacgc
    13801 ccgaagtcaa cgaaattgtg gtgaacccga atgcgaccct cgactggcaa ctggcactac
    13861 gccaggcagc aggaaaaacc gatttagcgc gcgatatgct gcaaatgtta ctcgatttcc
    13921 tgcctgaagt tcgcaacaaa gttgaggaac agctggttgg agaaaacccg gaaggcctgg
    13981 ttgatttgat tcataaactg catggcagtt gcggctatag cggtgtgccg cgtatgaaga
    14041 atctctgcca actgatcgaa caacagctac gtagcggtac taaagaagaa gatttggagc
    14101 cggagctgct ggaactgtta gacgagatgg ataatgtagc gcgcgaagcc agcaaaattc
    14161 tcgggtaacg gacgtcttgt cgagtagcaa tcggcttttt atgacgctgg tttcagattg
    14221 gtgacaaggt gcctgtgttt atgccggatg cggcgttaac gccttatccg gcctacaaaa
    14281 ccaattaaat tcaataaatt aaaaagtatg ttggcctgat acgtagcgca acaggcaatt
    14341 ttgcgtttgg tatcagtctc aaaccggctc ctgaaagagc cggttttggt tttctgtctt
    14401 aacgcaccat gcacgggcgc ttgttatcaa acgtccagcc aggaatcaga tactgcattc
    14461 ccatcgcatc gtctcgcgca ccaagcccgt gtttctgata cagctcgtgg gctttcatca
    14521 cctgatccat atcgatttct acgcccaatc ctggtttttg cggcacctgt accagcccgc
    14581 ctttgatctc aaacggttct ttggtcagac gctgattgcc ttcctgccag atccagtgcg
    14641 tatcaatagc agtaatttta cccggtgcag cagcggctac atgggtaaac atcgccaggg
    14701 aaatatcgaa gtggttgtta gagtgtgaac cccaggtcag gccaaattca tggcacattt
    14761 gcgccacacg taccgaacct tgcatcgtcc agaaatgcgg atccgccagc gggatatcaa
    14821 cggattgtaa cgagagcgta tggcccatct gccgccagtc ggtggcgatc atattggttg
    14881 cggtcggcag gccagtcgcg cgacggaact ccgccatcac ttcacgcccg gagaaacctt
    14941 gctccgcacc acacggatct tctgcataag ccagcgaacc tttcaggtat ttaccgattt
    15001 taatcgcttc gttcagcgac caggcaccgt taggatcgag ggtaatacgc gcctgtggga
    15061 agcgttgcgc cagtgccaca atagattctg cttcttcttc cccggccagt acaccgccct
    15121 tcagtttgaa atcgttgaag ccatattttt catatgccgc ttccgccagg cgcaccaccg
    15181 catccggcgt catcgcttct tcgtgacgca ggcgatacca gtcacattta tcatccggct
    15241 ggctttgata cggcagcggt gtggctttgc gattaccgac gaagaacaga taaccgagca
    15301 tttcgacttc gctacgctgt tgaccatcgc ccagcagcga tgccacgtta acccccagat
    15361 gctgccccag cagatccagc attgccgctt ctatcccggt aactacatga atagtggtcc
    15421 gcaggtcaaa tgtctgcaaa ccgcgcccac cggcatcacg atcggcaaat gtattacgca
    15481 ccagcgtcag aacgtttttg tattcaccca gcgttttacc caccaccagc ggaatcgcat
    15541 cttccagcgt tttacggatt ttctcgccgc cgggaatttc ccctacgcca gtgtgaccag
    15601 aattatcttt gataatcaca atattacgcg tgaagaacgg tgcgtgtgca ccactcagat
    15661 tcatcagcat actgtcatgg cccgccaccg ggatgacctg catttcagta acaacaggcg
    15721 tcgtaaattg agaactcata tttatgtcct ttttcaaaat caatgacggc cgaaaacggg
    15781 acgtttacgg tcaaaggtcc agccggggat caggtactgc atcgggcccg cgtcgttacg
    15841 cgcaccgcca ggcagacgtt tataggcctc atgcgccttt tgtacctgct cccagtccag
    15901 ttccacgccc agaccgggcg catcaggaac ggcaattttt ccgtttttaa tctccagcgg
    15961 atttttggtc aggcgacaat cgccctcctg ccaaatccag tgggtatcga tagcggtagg
    16021 attacccggt gccgccgcac ccacatgggt aaacatcgcc agagagatat caaagtggtt
    16081 attggaatgg cagccccagg tcagccccca gtcgtcgcaa agctgcgaca cgcggactgc
    16141 accggaaagc gtccagaagt gcggatcggc aagtggaata tctaccgcat tgagcatcac
    16201 cgcatggccc atttcgcgcc agttggtggc gatcatgtta gtcgcgacgg gcaagccggt
    16261 cgcccgtcga aactccgcca tcacttcacg tccggagaaa ccctgttctg cgccacatgg
    16321 atcttcggca taggtgagaa catcattcag ccctttgcac agagaaatag cttcatcaag
    16381 cagccatgct ccgttgggat caacggtaat ccgcgcatcc gggaagcgtt tcttcaatgc
    16441 acgaacagtg tcgatttctt gctcgccagg taacacgccg cccttaagtt tgaaatcttt
    16501 aaagccatag cgatcctgtg aagcttccgc cagacgcaca acggcttcgc tgttcatcgc
    16561 tttctgatgc cgcaattgat accactcatg gttgcccggc gtattttcca gataaggaag
    16621 atcggttttg gtccgatcac cgatataaaa cagataaccg aggacggtaa tagcatcgcg
    16681 ttgcttgcct ggccctaaca gttcgcagac cggaacattc agcgccttac ctagcaggtc
    16741 aagcaaggcg gcttccagcg ccgccacggc attaacgcgc aattcaaaag tccaggcacc
    16801 tttgccgaag gtatcaaaat cggctgcctg attaccttta tgcacctgct gaaccacttt
    16861 attcagtcgt gcgatctcct ggcccaacac catcggaata gcatcgacca gtgtttgata
    16921 aatcacctct ccgcctggcg cttcaccaat gccggaatgt ccggcattat cggtgagtac
    16981 cacgatattg cgggtgaaat atgcgttatg tgcaccacca atattaagca acatgctgtc
    17041 atgcccggcc accggaatga ctttcatatc agtaataaca ggactggatt gtgtcgtcat
    17101 cttattgccc cgcgacaggt ttcagctcga tacgcttgat atcgcccacc agcaccaggt
    17161 agctcagcac cgcgattaag gcatgaacac caacataaat cagcgcccca ttaaacgagc
    17221 cagtcgtgcc aacgatataa ccaattgcga ttggcgtgac gatgccagaa atgttaccga
    17281 acatgttgaa caggccaccg gaaagaccgc tgatctcttt tggcgcggta tctgccatta
    17341 ctgcccaacc cagcgccccg atgcccttac cgaagaaggc cagcgccata aaaccgatga
    17401 tcatccactc aacgttgacg tagttgcaga acaccatcac catcgacagc aacatgccca
    17461 ttacgatcgg tgttttacgc gcaatgttca gcgatcccgt gcggcgcatc agccagtcgg
    17521 aaataatccc acccagcaca ccgccgataa aaccgcaaac cgccggaacg gaagccacaa
    17581 agcccgcttt cagaatcgac atcccacgcg cctgcaccag ataaaccgga aaccaggtaa
    17641 tgaaaaagta agtcagggcg ttgatacagt actgaccgat ataaacgccg atcatcatcc
    17701 gtgacccgag cagctgtttg atctgccccc acttcacgct gaacggcact ttaactttgg
    17761 tattttgctg atccatattg atcagcgcgc cacccgcggc gatgtactcc agctctttct
    17821 gatttacacc cggatgttga tttggctcgt ggatgacttt caaccagata aagctgatga
    17881 caatgcccag accgcccata aagaagaaga cgtgtgacca gcccacttca tgcgtcagcc
    17941 agcccataat cggcgcgaag atcaccgttg cgaagtattg agcggagtta aaaatcgaca
    18001 ccgccgttcc cctttcctgc gccggaaacc aggccgcaac aatgcgactg ttgccgggga
    18061 aagatggcgc ttcagcaagc ccgaccagga agcgcagcgt aaacagggca acgataatgc
    18121 cgaatccact aaaaatatcg acgaagcctt gcagcaaggt aaacatcgac cagataaaga
    18181 tcgaccagaa gtagacgcgt tttgaaccaa aacgatccag caaccaacca ccagggatct
    18241 gtccgataac ataagcccat gagaaagcag agaacacata gcccattccc acgggatcaa
    18301 ggccgatatc tttggccatt tccgaaccgg caatagaaag cgtagcgcgg tcgccgtagt
    18361 tgaaggatgt gacgataaac aacatcacca ctatccagta acgagcattt gtgcgttttt
    18421 ccacactgct cgcagcctga cttaaagaac tcattgttgc actcctgaaa attcgcgtta
    18481 gccacgctca ctctggactg cgacatcgcc aggaaatcag aggtgacgta gggtgttttt
    18541 tgccgttttt ataggtcgtt cgccgaatac ggcgcgtgtt tatatctggc aatagcagta
    18601 taaaaagcgc gccatagcgg ctcaccgtgc aacaacacaa cattaatgcg ttcaatgagg
    18661 cccgattttg gcattagccc tggacggtgg aatccacttc acggaaatga aaacaagaac
    18721 aagaaaggaa gggttaaaac gaagaaataa agaagagtat gaaatggatc gcttgactcc
    18781 aggcaaacgc cagtaaaaat ccgcgctatg aagcagtttt tactggcatt tgcctgaaaa
    18841 gattcgattc agcaccgcta aaacggcatt taccgctcgc tgaacgtatc aggacaacag
    18901 cgtgccccaa tgttcgaccc acggatttga ttccgtttcc ggttccgggt tctcactggc
    18961 gtcaatcaac agcatttcgc caacccgctg agcgctctgt tcctgcaaca aggcatcgaa
    19021 ctgtttgccg ccattgcaga aattcacata actactgtcg ccgagcgcaa tcacgccata
    19081 acgcagattc ggctggaagc ccagactatc tttgattccc tgaaagagcg gcacaatgct
    19141 atcaggaagg tcgccctgcc cggtcgtgga cgtaaccacc agaacatact tatcctgata
    19201 gggcagccag tcgcttaatt caggatcttc aaataccgtt gctttgtggc cctgcgcggt
    19261 cagaattgct tccgcttctt ccgccactaa cagcgaattt ccgtacatag tgccgacaaa
    19321 aataccaatt tccgccatac cgttttctcc ctggattagg aacttatctc tccatcctga
    19381 cccgatggcg cactgaactc aaccctttca ttttcaggaa gcagaccccg ccagccaaat
    19441 tgtgataacg cctgcatcca ggtgtcgtcc aggcccgcgt gaatagtcag cggctcgcca
    19501 gtaaaaggat gcgtcaatga caactgactg gcatgcagca ttaaccgctg aaggccaaaa
    19561 tgttcagcac cgctgcgatt ctggcgtaaa tcaccatgtt tgctgtcgcc aataatcggg
    19621 tggcgcaaat gggcaagatg gcgacggagc tggtgcttac gtccagtttt cggctccagt
    19681 tccaccaggc cgtagcgcgt ggtcgggtaa cgtccggtcg ctatcggcat ttctacggtc
    19741 gccagaccgc gataatgcgt cactgctggc tgtgggcctt tatcttcgcg ggcaaattta
    19801 tcagcgattt tgtccagttc ttccaccagt ggataatcca gaactgcttc ttccatcaac
    19861 cagccgcgca caatcgcatg gtaacgtttc tggatttggt gctgttcaaa ctgttgtgcc
    19921 agcagccgtc cggcctcgct ggataatccc atcaacaaca caccagaagt gggtcggtcc
    19981 agacgatgag cagtaaacac atgctggcct atctggtcac gcacggtttg catgaccact
    20041 actttctcgt cgcgatccag ccagctgcgg tgaaccagcc agccggaggg tttatttacc
    20101 gcaaccagcc attcatcctg atagagtatt tccagcatta gctcgcatca tccgcaaaaa
    20161 gagcatccag tttttccagc tcagccagaa taagcgcgcg ttgcgggtgg tccgtcgcca
    20221 gcgccatttc ataatagggt gcaacggcaa aagcgcccgg taacggctgg ttgttatcta
    20281 acaaatcgtg cattcgcggg atcagcaccc actgcaacca ctccagtggt tccatggtgt
    20341 ccataaagaa cggttgggta ctgttaaatt gatgcggctg gggttcatcg ttttgccagt
    20401 gctgatgttc acgcagtaat gcttcaagcg cctgcagctg gagacgaacg cggtcatgag
    20461 tggtcataaa gcaacctcaa taagaaaaac tgccgcgaag gatagcagga ataaaaaaag
    20521 ggagcactgt attcacagtg ctcccggttc gtttcgcagc attccagcta cttttgttgc
    20581 tccctgctca tccttgacaa cttttcctct ggccttgcgg ccaatcgttc atcctgaact
    20641 attgcttcct gctcacacca ccccgatgtg atacttcatc ctgaagtgtc cctggccttc
    20701 ctgacccacc gaatcatcct gaccggttct cattctccat cctggaggtg tcctttaacg
    20761 cgtcctgcgt catcctcttc gcttcatcca gaagcctttc cctgaaacac catcctggtg
    20821 tgtccttcag aagtgtcatc atcctgatgt tcacttcgtt gtctgactcc ctgtcgacga
    20881 agatagaatc gtctttttcg cgaagactta caaggcgctt acagacaatg ccttaaggaa
    20941 aatttcatat gaaagttaag aattgacaag caatatattg attttaaatg aaaataacga
    21001 ttcttatctt tttaagtatt cgcttatttc ctggcgatct cctacagagt ctgtaagaga
    21061 tctctcacaa ccagatgggg tatttggatt acagaagagg cttaagttga ttaaggaatt
    21121 ccgcaagatt tgaggctaaa tgcgtccgtt tacgtgttcc cagcgtctct ttgcacactt
    21181 caccggagag attacacacc gagatgacct ctaactcttc ttccagcgtc gcgataaata
    21241 gcgtgggcgg cagttttagc cttttctgag tcaccagatg accaatcaga ttttcctgca
    21301 cccgacggaa atcgtcttca ctccaggttt gcagcaatgt cagtttgata tcgccaaact
    21361 gcgcgtgcat atccccggca aactgagtcg tataaaaggt atgaatcgtg ggttgtatca
    21421 caatatcaaa agcgcgttca accgcgttta cattttgttc cccggtaaac ggctggggtt
    21481 gccagtatac ggcatcttcg gtagttgaaa taatgcacgg tgaaggaacg ccgtacagtt
    21541 cctcactcaa cggccagctt ttatgctctt catgccacgc atcgcagtaa catgcagtaa
    21601 aatctttcag ggcttgtgcg gtcaaatcgt ccactaattt ctctcttcac ttaaaccaga
    21661 tacacttgtc gtttagttta tctggtttat gacggtgaaa catgtcttct tatgcaaacc
    21721 atcaggcact tgcgggcctg actcttggaa aatcaaccga ttaccgggat acctatgacg
    21781 ccagcctact gcaaggcgtt ccgcgtagtc tgaatcgcga tccgctgggt ctgaaagcgg
    21841 ataacctgcc ttttcacggt acggatatct ggacgctata tgaactttcc tggctgaatg
    21901 cgaaaggttt gccgcaggtc gccgtcggtc atgttgaact tgattacacc agcgcaaatc
    21961 tgattgagtc gaagagtttt aagctctatc tcaacagttt taaccagacg cgttttaata
    22021 actgggatga ggtgcgccag acgctggagc gcgacttaag cacttgcgct cagggtaagg
    22081 ttagcgtggc gttatatcgt cttgatgaac tggaaggcca accgataggt catttcaatg
    22141 gcacttgcat tgatgaccag gatatcacta tcgataacta tgaattcact actgactatc
    22201 tggagaatgc caccagtggc gaaaaagtag tagaagagac gctcgtcagc cacctgctga
    22261 aatcaaattg cctgatcacc catcaaccag attggggatc gatccaaatt cagtatcgtg
    22321 gacgccaaat tgacagagaa aaactgctgc gttacctggt ttctttccgt catcacaacg
    22381 agttccacga acagtgcgtg gaacgcatct ttaatgacct gttacgcttc tgccagccag
    22441 agaaattgag cgtttacgca cgttataccc gtcgtggcgg tctggacatt aacccgtggc
    22501 gcagtaatag cgattttgtc ccatcgacca caagactggt tcggcaataa attttttctc
    22561 aattttgcgt gctggattca cgcagaaggt tgtgaaaggt catcaggcag ggctattgta
    22621 atcaaaggga atgacgatat tcgtcccata aggagttttt cttgattaca catattagcc
    22681 cgcttggctc catggatatg ttgtcgcagc tggaagtgga tatgcttaaa cgcaccgcca
    22741 gcagcgacct ctatcaactg tttcgcaact gttcacttgc cgtactgaac tccggtagtt
    22801 tgaccgataa cagcaaagaa ttgctgtctc gttttgaaaa tttcgatatt aacgtcctgc
    22861 gccgtgaacg cggcgtaaag ctggaactga ttaatccccc ggaagaggct tttgtcgatg
    22921 ggcgaattat tcgcgctttg caggccaact tgttcgcggt tctgcgtgac attctcttcg
    22981 tttacgggca aatccataac accgttcgtt ttcccaacct gaatctcgac aactccgtcc
    23041 acatcactaa cctggtcttt tccatcttgc gtaacgctcg cgcactgcat gtcggtgaag
    23101 cgccaaatat ggtggtctgc tggggcgggc actcaattaa cgaaaacgag tatttgtatg
    23161 cccgtcgcgt cgggaatcag ctgggcctgc gtgagctgaa tatctgcacc ggctgtggtc
    23221 cgggagcgat ggaagcgccg atgaaaggcg ctgcggtcgg acacgcacag cagcgttaca
    23281 aagacagtcg ttttattggt atgacagagc cgtcgattat cgccgctgaa ccgcctaacc
    23341 cgctggtcaa cgaattgatc atcatgccag atatcgaaaa acgtctggaa gcgtttgtcc
    23401 gtatcgctca cggtatcatt atcttccctg gcggtgtggg tacggcagaa gagctgctgt
    23461 atttgctggg aattttaatg aacccggcca acaaagatca ggttttacca ttgatcctca
    23521 ccggcccgaa agagagcgcc gactacttcc gcgtactgga cgagtttgtc gtgcatacgt
    23581 tgggtgaaaa cgcgcgccgc cattaccgca tcatcattga tgacgccgct gaagtcgctc
    23641 gtcagatgaa aaaatcgatg ccgctggtga aagaaaatcg ccgcgacaca ggcgatgcct
    23701 acagctttaa ctggtcaatg cgcattgcgc cagatttgca aatgccgttt gagccgtctc
    23761 acgagaatat ggctaatctg aagctttacc cggatcaacc cgttgaagtg ctggctgccg
    23821 acctgcgccg tgcgttctcc ggtattgtgg cgggtaacgt aaaagaagtc ggtattcgcg
    23881 ccattgaaga gtttggtcct tataaaatca acggcgataa agagattatg cgtcgtatgg
    23941 atgacctgct acagggtttt gttgcccagc atcgtatgaa gttgccaggc tcagcctaca
    24001 tcccttgcta cgaaatctgc acgtaatctc cctcccccgg tgacgtttgt tgccgggttt
    24061 tctcg
//
LOCUS       DACAOP010000069        24020 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.069, whole genome shotgun sequence.
ACCESSION   DACAOP010000069 DACAOP010000000
VERSION     DACAOP010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24020
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.069"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            72..704
                     /gene="comR"
                     /locus_tag="IT892_003004"
     CDS             72..704
                     /gene="comR"
                     /locus_tag="IT892_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415629.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family copper-responsive transcriptional
                     repressor ComR"
                     /protein_id="HAP3136195.1"
                     /translation="MATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLAD
                     LVEATGAKAPTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFA
                     AIANCFTSKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGE
                     IPPHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK"
     gene            complement(766..1305)
                     /locus_tag="IT892_003005"
     CDS             complement(766..1305)
                     /locus_tag="IT892_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HAP3136196.1"
                     /translation="MNKSMLAGIGIGVAAALGVAAVASLNVFERGPQYAQVVSATPIK
                     ETVKTPRQECRNVTVTHRRPVQDENRITGSVLGAVAGGVIGHQFGGGRGKDVATVVGA
                     LGGGYAGNQIQGSLQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDRD
                     PGTQIPLDSNGQLILNNKV"
     gene            complement(1515..2819)
                     /locus_tag="IT892_003006"
     CDS             complement(1515..2819)
                     /locus_tag="IT892_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAP3136197.1"
                     /translation="MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHS
                     HLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDE
                     KGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLK
                     YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGE
                     RILPALPPRISAAAHNELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGI
                     KAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAA
                     HQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRI
                     ARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH"
     gene            complement(3219..3761)
                     /locus_tag="IT892_003007"
     CDS             complement(3219..3761)
                     /locus_tag="IT892_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP3136198.1"
                     /translation="MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQ
                     HLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKI
                     DRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQT
                     HKFKNISPHLQRIKAFKTLG"
     gene            complement(3784..4809)
                     /gene="nagZ"
                     /locus_tag="IT892_003008"
     CDS             complement(3784..4809)
                     /gene="nagZ"
                     /locus_tag="IT892_003008"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HAP3136199.1"
                     /translation="MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRE
                     LVRQIRAASRNRLVVAVDQEGGRVQRFREGFTRLPAAQSFAALSGMEEGGKLAQEAGW
                     LMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKT
                     TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSD
                     VDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMI
                     LVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISTRLNQLHERW
                     QEEKAGH"
     gene            complement(4820..5644)
                     /gene="thiK"
                     /locus_tag="IT892_003009"
     CDS             complement(4820..5644)
                     /gene="thiK"
                     /locus_tag="IT892_003009"
                     /EC_number="2.7.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine kinase"
                     /protein_id="HAP3136200.1"
                     /translation="MPFRSNNPITRDELLSRFFPQYHPVTTFNSGLSGGSFLIEHQGQ
                     RFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGAVKTYLPD
                     TNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRP
                     LRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHRQLVNDYA
                     TRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ"
     gene            complement(5625..6266)
                     /gene="lpoB"
                     /locus_tag="IT892_003010"
     CDS             complement(5625..6266)
                     /gene="lpoB"
                     /locus_tag="IT892_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HAP3136201.1"
                     /translation="MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPAEPQQ
                     PVPTVPSVPTIPQQPGPIEHEDQTAPPAPHIRYYDWNGAMQPMVSKMLGADGVTAGSV
                     LLVDSVNNRTNGSLNAAEATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGT
                     RSKAIGIARNVGAHYVLYSSASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ"
     gene            complement(6280..6657)
                     /locus_tag="IT892_003011"
     CDS             complement(6280..6657)
                     /locus_tag="IT892_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcfL family protein"
                     /protein_id="HAP3136202.1"
                     /translation="MRKGCFGLVSLVLLLLVGCRSHPEIPVNDEQSLVMESSLLAAGI
                     SAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAH
                     SAVTLYGSANFLGAHKVRLYLYL"
     gene            complement(6660..7019)
                     /gene="hinT"
                     /locus_tag="IT892_003012"
     CDS             complement(6660..7019)
                     /gene="hinT"
                     /locus_tag="IT892_003012"
                     /EC_number="3.9.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415621.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphoramidase"
                     /protein_id="HAP3136203.1"
                     /translation="MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIP
                     NILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHM
                     HLLGGRPLGPMLAHKGL"
     gene            7353..9542
                     /gene="fhuE"
                     /locus_tag="IT892_003013"
     CDS             7353..9542
                     /gene="fhuE"
                     /locus_tag="IT892_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric-rhodotorulic acid/ferric-coprogen
                     receptor FhuE"
                     /protein_id="HAP3136204.1"
                     /translation="MLSTQFNRDNQYQAITKPSLLAGCIALALLPSAAFAAPATEETV
                     IVEGSATAPDDGENDYSVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVM
                     ENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
                     VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDG
                     KIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTWG
                     GLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQQFADTWQATLNATHSEVE
                     FDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYEL
                     FGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTT
                     HMKSLYAATRVTLADPLHLILGARYTNWRVDTLTYSMEKNHTTPYAGLVFDINDNWST
                     YASYTSIFQPQNDRDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQ
                     STGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVN
                     PNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLF
                     TRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGTPRNFSITGTYQF"
     gene            complement(9602..11035)
                     /gene="ptsG"
                     /locus_tag="IT892_003014"
     CDS             complement(9602..11035)
                     /gene="ptsG"
                     /locus_tag="IT892_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HAP3136205.1"
                     /translation="MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVV
                     SHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLH
                     LPAEEIASKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
                     AIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPF
                     QMQIGEYTNAAGQVFHGDIPRYMAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPEN
                     RAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDG
                     TSFSHGLIDFIVLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGREDATED
                     AKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVV
                     AGSGVQAIFGTKSDNLKTEMDEYIRNH"
     gene            complement(11330..12127)
                     /locus_tag="IT892_003015"
     CDS             complement(11330..12127)
                     /locus_tag="IT892_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP3136206.1"
                     /translation="MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTL
                     PGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYT
                     PETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
                     RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKE
                     NQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR"
     gene            complement(12138..13142)
                     /gene="holB"
                     /locus_tag="IT892_003016"
     CDS             complement(12138..13142)
                     /gene="holB"
                     /locus_tag="IT892_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAP3136207.1"
                     /translation="MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYAL
                     SRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNTLGVDAVREVTEKLNE
                     HARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR
                     LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQ
                     ALAYSVPSGDWYSLLAALNHEQAPARLHWLATLLMDALKRHHGAAQVTNVDVPGLVAE
                     LANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIEHYLQPGVVLPVPHL
                     "
     gene            complement(13139..13780)
                     /locus_tag="IT892_003017"
     CDS             complement(13139..13780)
                     /locus_tag="IT892_003017"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAP3136208.1"
                     /translation="MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGT
                     QLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHD
                     LSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIE
                     QESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA"
     gene            complement(13770..14792)
                     /gene="yceG"
                     /locus_tag="IT892_003018"
     CDS             complement(13770..14792)
                     /gene="yceG"
                     /locus_tag="IT892_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YceG"
                     /protein_id="HAP3136209.1"
                     /translation="MKKVLLIILLLLVVLGIAAGVGVWKVRHLADSKLLIKEETIFTL
                     KPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLL
                     ESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGW
                     FWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKE
                     TAVASERDKVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTI
                     TGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVL
                     KEKNAQ"
     gene            complement(14795..15604)
                     /gene="pabC"
                     /locus_tag="IT892_003019"
     CDS             complement(14795..15604)
                     /gene="pabC"
                     /locus_tag="IT892_003019"
                     /EC_number="4.1.3.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HAP3136210.1"
                     /translation="MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQ
                     RLQDACQRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATR
                     ILSVTAYPAHYDRLRNEGITLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNAD
                     EALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVE
                     VQASLEESLQADEMVICNALMPVMPVCACGDVSFSSATLYEYLAPLCERPN"
     gene            complement(15724..16965)
                     /gene="fabF"
                     /locus_tag="IT892_003020"
     CDS             complement(15724..16965)
                     /gene="fabF"
                     /locus_tag="IT892_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAP3136211.1"
                     /translation="MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTS
                     AYATKFAGLVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIG
                     AAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISI
                     ATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQA
                     ASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPEN
                     GAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSS
                     TKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGME
                     YTLCNSFGFGGTNGSLIFKKI"
     gene            complement(17053..17289)
                     /gene="acpP"
                     /locus_tag="IT892_003021"
     CDS             complement(17053..17289)
                     /gene="acpP"
                     /locus_tag="IT892_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP3136212.1"
                     /translation="MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELV
                     MALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA"
     gene            complement(17500..18234)
                     /gene="fabG"
                     /locus_tag="IT892_003022"
     CDS             complement(17500..18234)
                     /gene="fabG"
                     /locus_tag="IT892_003022"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HAP3136213.1"
                     /translation="MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQA
                     ISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEE
                     WNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIG
                     FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANA
                     VAFLASDEAAYITGETLHVNGGMYMV"
     gene            complement(18247..19176)
                     /gene="fabD"
                     /locus_tag="IT892_003023"
     CDS             complement(18247..19176)
                     /gene="fabD"
                     /locus_tag="IT892_003023"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP3136214.1"
                     /translation="MTQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDL
                     WALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCA
                     GVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVN
                     FNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAK
                     ITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVG
                     PGKVLTGLTKRIVDTLTASALNEPSAMAAALEL"
     gene            complement(19192..20145)
                     /locus_tag="IT892_003024"
     CDS             complement(19192..20145)
                     /locus_tag="IT892_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAP3136215.1"
                     /translation="MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHI
                     AAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKG
                     CPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDG
                     AGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVT
                     ELAHIVDETLAANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTS
                     AASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF"
     gene            complement(20213..21283)
                     /gene="plsX"
                     /locus_tag="IT892_003025"
     CDS             complement(20213..21283)
                     /gene="plsX"
                     /locus_tag="IT892_003025"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415608.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAP3136216.1"
                     /translation="MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDA
                     ITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGSSMRVALELVKEGRAQAC
                     VSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQ
                     FAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEAN
                     ELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKS
                     LTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAA
                     RLESVYPAGFELLDGGKSGTLR"
     gene            complement(21364..21537)
                     /gene="rpmF"
                     /locus_tag="IT892_003026"
     CDS             complement(21364..21537)
                     /gene="rpmF"
                     /locus_tag="IT892_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP3136217.1"
                     /translation="MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHIT
                     ADGYYRGRKVIAK"
     gene            complement(21589..22110)
                     /gene="yceD"
                     /locus_tag="IT892_003027"
     CDS             complement(21589..22110)
                     /gene="yceD"
                     /locus_tag="IT892_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA accumulation protein YceD"
                     /protein_id="HAP3136218.1"
                     /translation="MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSD
                     VECSMSFAIDNQRLAVLNGDAKVTVTLECQRCGKPFTHQVYTTYCFSPVRSDEQAEAL
                     PEAYEPIEVNEFGEIDLLAMVEDEIILALPVVPVHDSEHCEVSEADMVFGELPEEAQK
                     PNPFAVLASLKRK"
     gene            22309..22893
                     /gene="yceF"
                     /locus_tag="IT892_003028"
     CDS             22309..22893
                     /gene="yceF"
                     /locus_tag="IT892_003028"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-methyl-GTP pyrophosphatase"
                     /protein_id="HAP3136219.1"
                     /translation="MPKLILASTSPWRRALLEKLQISFECAAPEVDETPRSDESPRQL
                     VLRLAQEKAQSLASRYPDHLIIGSDQVCVLDGEITGKPLTEENARLQLRKASGNIVTF
                     YTGLALFNSANGHLQTEVEPFDVHFRHLSEAEIDNYVRKEHPLHCAGSFKSEGFGITL
                     FERLEGRDPNTLVGLPLIALCQMLRREGKNPLMG"
     gene            complement(23005..23964)
                     /gene="rluC"
                     /locus_tag="IT892_003029"
     CDS             complement(23005..23964)
                     /gene="rluC"
                     /locus_tag="IT892_003029"
                     /EC_number="5.4.99.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(955/2504/2580) synthase
                     RluC"
                     /protein_id="HAP3136220.1"
                     /translation="MKTETPSVKIVAITADEAGQRIDNFLRTQLKGVPKSMIYRILRK
                     GEVRVNKKRIKPEYKLEAGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHI
                     LVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSAL
                     RSLHEQLREKGMQKDYLALVRGQWQSHVKSVQAPLLKNILQSGERIVRVSQEGKPSET
                     RFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDRQLTEAGTG
                     LNRLFLHAAALKFTHPGTGEVMRIEAPMDEGLKRCLQKLRNAR"
BASE COUNT         5909 a         6527 c         5809 g         5775 t
ORIGIN      
        1 ctggactggt gaacggaggt gattattttt ataataacct ttcattcaca gtcaccaggt
       61 acaacggcat catggcaact gactcaacac aatgtgtaaa aaaaagccgt ggccgcccaa
      121 aagtgttcga cagggatgcc gcgcttgata aggccatgaa attgttctgg caacacggtt
      181 atgaagcgac ttctcttgcg gacctcgtcg aagcgaccgg agccaaagcg cccacgctat
      241 acgcggaatt taccaacaaa gaggggttat ttcgtgccgt tctcgaccgc tatatcgatc
      301 gttttgccgc taagcatgaa gcacagctgt tttgtgaaga gaaaagcgtg gagtctgcgc
      361 tggctgacta ttttgctgcc atcgccaact gctttaccag caaagacacc ccggcaggct
      421 gcttcatgat caacaactgc accaccctct ccccagattc aggagatatc gccaatacgt
      481 tgaaatcacg ccatgcgatg caagagcgca ctttgcagca gtttttatgt caacgacaag
      541 cgcgcgggga aatcccgccc cactgtgacg tgacacatct ggcagaattc cttaattgta
      601 ttattcaggg gatgtcgatc agcgcacgcg aaggtgcatc gctggaaaaa ctgatgcaga
      661 ttgccggaac gactttgcgt ttatggcccg aactggtgaa ataagtcgca aaaaaagccc
      721 ctcagcctga gcgaatgagg ggccaaattg cagagtacag ccttgttata ctttgttatt
      781 caaaatcagt tgcccgttgc tatctagcgg gatctgcgta cccggatcgc ggtccatgcg
      841 gattttgccc tgctgatcgc caatcttata ggtcacatca taaccgagca ttttttctga
      901 cttgtcatac accgttttac aacgctgttg cgtagtcgtg taagtatcgc tttcctggag
      961 agagccctgg atctggttac cggcatatcc accacccagc gcccccacaa cagtggcgac
     1021 atctttaccg cgaccaccac caaactgatg ccctatcacg ccgccagcaa cagcgccgag
     1081 caccgacccg gtaatgcgat tttcatcctg caccggtcga cgatgggtca ctgtgacgtt
     1141 gcgacactcc tgacgcggtg ttttaaccgt ttccttgatt ggggttgcag aaacaacctg
     1201 agcgtattgc gggccccgtt caaacacgtt cagactggcc actgccgcta cgcccagcgc
     1261 agctgcgaca ccaatcccga tacccgccaa cattgattta ttcacgggaa cacctccttc
     1321 tttgcagtta tgccaatcat gcaagcgaag gagaaaagca gctatcagac agaagatgaa
     1381 aagcgcggga atggctggaa atacttaagg attcggagga gtctgaaagg atgcctgata
     1441 caacgcggct gccgatcgcg ctgttcctca agggcggatg aggcgtttat gccacatccg
     1501 ccagtgtacg tcgattaatg caacttcaaa cgcggacgga taacgcggtt aatactcccc
     1561 accagcatca ttaatccggt tttaaagtaa ccatgcagcg caatctgatg cattcggtat
     1621 agcgagatat atacaaagcg cgcaattcgt ccttcaatca tcattgagcc gcgcgtcagg
     1681 ttacccatca ggctaccgac ggtggagaag ttcgacagcg ataccagcga accatgatct
     1741 ttatactgat aatttttcag cggcttaccg ttcatctgcg ccagaatgtt gttcattgcg
     1801 caagtcgcca tctggtgtgc agcctgagca cgcggcggaa caaagccccc ttccggacgc
     1861 gggcatgacg cgcagtcgcc aatagcgtaa atgtctggat cgcgggtggt ttgcagcgtc
     1921 ggttccacca ccagctggtt gatacggtta gtttcaagac caccgatatc tttcaggaag
     1981 tctggcgctt tgatcccggc tgcccatacc atcagatcag cctcaatata ttcgccatct
     2041 ttagtgtgca ggccgccttc atcagcactg gtgaccatgg tttgcgtcag cacgcgaacg
     2101 ccaagtttcg ttagctcgtt gtgggccgca gcagagatac gtggcggtaa cgcaggcaaa
     2161 atacgttctc ccgcttctac cagcgttacg ttcagggctt cgttggtcag gcctttgtaa
     2221 ccgtagctgt gcagttgctt gaccgcgttg tgcaattcag cggagagttc tacacccgtc
     2281 gcgccgccgc cgacaatcgc aatgttcact ttgccattcg cgcccaggtt ggcggagtat
     2341 ttcaggaaca aattcagcat ctcctggtgg aagcgacgcg cctggtgcgg gttatcgagg
     2401 aaaatgcagt tctctttgac acctggcgta ttgaaatcgt tagaggtgct acccagcgcc
     2461 attaccaggg tgtcataggc gattttacgt tccggaacca gcagttcacc tttctcgtcg
     2521 cgcagttctg caatagtgat tgttttcgct tcacgatcaa tatcaatgac ggaacccagc
     2581 tggaactgga aaccatgatt gcgcgcatgg gccagatagc tcaacgcatc gacgccttca
     2641 tcaagcgagc cagtcgccac ttcgtgcagc agcggtttcc acaggtggct gtggttacga
     2701 tcgaccagcg taattttggc ttttttcttg cgtcccagct tatgccccag ctgtgttgcc
     2761 atttccagcc caccagcacc gccgccgaca atcacaatct ttttcaatgg cgtagtcaac
     2821 gtgaccccct taaatttatt aaccaattgt taattaatgg ttattaacat agctcttaat
     2881 taacaacagg ttacagcaat gaaaatgttc ttcgctattg agaataacat gaatggtgca
     2941 ttggtcatac caaaattgat gttaatcaag ttttgttgct gaaaagatag gcgactttac
     3001 cgggtgagat caaaaaacag agtttattgt ttattatttg agcgaatttg tgagagtgat
     3061 atagagtgag gggtgtatgc agggcgttcg gtaggcctga taagaagcgc atcaggcatt
     3121 gatgctcgac tgtcggatgc ggcgtggacg ccttatccga cccacagaat tcggagcgca
     3181 tcaggtaccg gcaaggttac ctgatgcgac gagggcattt acccgagggt tttgaacgct
     3241 ttaatgcgct gtaaatgcgg ggagatattc ttgaatttgt gcgtctgctc ttcgtcccag
     3301 acaatctcgt aataatgatg caactcttca gatgtccgct ggctgttaag cgcttcatca
     3361 ttacgcgaca aaatcaccag gcaacgatcg cgattcttct cacggaagtt ggtcacacac
     3421 ttagtggcaa tatcggcata ctcttccggg cgatcaatct tgccttccat gttctcataa
     3481 gggaacaaat tagggttgaa gatcacctgg cggatgtcgc aaagaaaacc aatccgttcc
     3541 gcccagtatc cgcccaagcc aacgccgcaa attagcggac gctcgtcaac gttcagttgc
     3601 aacattttgt ccacttcttt aagcagatgc tgcatatcat gtttcggatg ccgcgtactg
     3661 tagcttatca agcgtacatc cgggtcaata aactgcaatt gtaagacttt ctcgtggtta
     3721 cccggactgt tagagtcaaa accgtgtaaa tagataatca tcgcttcctc acataagcca
     3781 gggttagtga cctgctttct cttcctgcca gcgttcatgt aactgattca gacgggtgct
     3841 gatcgctttc cagcgagccg agtccatcag ttcctgtcgc gaaaatgaac ctttatgata
     3901 caaacgtgta acacgttctg ccttgatcgg tgacagatta tctaacacgc tgacggcccc
     3961 tttacgatta ttgcagacca ggatcatatc gcaacccgca tccagtgaag cctgcccgcg
     4021 ttcggcataa ctgcccataa tcgcggcacc ttccatcgat aaatcgtcag agaaaatcac
     4081 gccgtcaaaa cccagttcct gacgcaaaac ggttttcagc cagtagggag aaccgctcgc
     4141 cggacgcgga tcaacatcac tgtagatcac atgcgcaggc ataatggcgt cgagtttatt
     4201 ttcgcggatt aaggaactga agaccgacat atctttagcg cgaatctccg cttgtggacg
     4261 tggatcgcac ggtgtttctt tgtgtgagtc tgccgttact gcaccgtgtc ctgggaagtg
     4321 tttcccggtc gttttcattc cggcttcatg cataccatca ataaaccggc tggcaattgc
     4381 cagggctttt tgtggatcgg catgataaga acgctcgcca atcgccgcgc tgatatgccc
     4441 gacatccagc acaggcgcaa agctgatatc aatatccata gcgatcattt cgctggccat
     4501 caaccaacct gcctcctgcg ccagtttgcc accctcttcc attcctgaca gcgcagcgaa
     4561 tgattgcgcc gctggcaagc gggtaaaacc ttcacgaaaa cgctgcacgc gtccaccttc
     4621 ctgatcaacc gccaccacca gacgattgcg cgaagctgcg cggatctggc gcaccagttc
     4681 acgtaactgg gcaggatcat gatagttacg cgtaaagaga atcagccctc ccaccagcgg
     4741 atgcgccagt atttcacgct cttccgcgtc cagttcgtaa ccttcgacat ccaacattac
     4801 tggacccaca ctgctctcct tattgtttta ttaatagctg ccgccaggtg tcatcggcca
     4861 gcctgataaa ttgttgatcg ccggtttgtc gccagcggta ctcaaaccac cctgctttga
     4921 gcatcagcag ccagggaaac catcgcctga cctgacgcca taattgcgcc ggataaatct
     4981 tcgcgcgagt ggcatagtca ttgaccaatt gccggtgctg ttcagtattt tccacccaca
     5041 ccgccgccag ttccagcgcg atatcaccat ctccggcata ctcccagtcg atgagtttta
     5101 accctgacgc gctatgcact aaatttccgg cgtggacatc catatgcaat ggacttaagc
     5161 gtaaaggccg tggttcccgc gctttgcgca gacgttttaa cattcgcagc caacccactg
     5221 tccgccgcgc cggatcgctt tgctgccagt acagttccag taacggcaac agcgttattc
     5281 gccagccaaa acgtggttgt tgatgtagat aatacagcaa gcctgccagt tcgttggtat
     5341 ccggcaaata cgtttttacc gcgccgggca gatagtcgac taccatccag tcacggagat
     5401 ataaatgcgg cttcggtgca atgcatgcgg gtagttgtga taaagcccga tactggcgca
     5461 agaacgcgga ctgcggcgca tcaggatcgt gcggctgacg cacaacaaaa cgctggccct
     5521 gatgttcaat gagaaaactc ccgccactaa gcccactatt aaacgtcgtg acgggatgat
     5581 actgcgggaa aaagcgcgac agcaattcgt cgcgcgtgat gggattattg ctgcgaaacg
     5641 gcacctttac ctgaccagat aatttcgccc gtctgcacca gcatcagctg catttgtagg
     5701 gtcggagcgt taacgttgcc agaggcgctg gagtacagca cgtaatgagc gccgacattg
     5761 cgggcaatgc ctatggcttt actacgggtg cctaaactgt cctgcggcga caaacctaac
     5821 tgttgcttcg ccatcgacag ttgctgggcg gaaaccaggg taaatttccc gttattagcc
     5881 agcgcatttc gcagcgtttc ggtcgcttct gcggcattca gcgaaccgtt agtacggttg
     5941 ttaacgctat caaccagcag gacgctaccc gcagtcaccc cgtcagcccc aagcatctta
     6001 ctgaccatcg gctgcattgc gccattccag tcataatagc gaatatgcgg cgcaggcggt
     6061 gcagtttgat cttcgtgctc aattgggcct ggctgctgcg ggatcgtcgg caccgagggc
     6121 actgtgggga caggctgttg tggctcggct ggttgttccg gcgctggttt cacttcttct
     6181 accggtgcag gttcacgttg ccccacacac ccggcgagaa acatcgccag cgcggtaatc
     6241 aaggcgtagc gactcatttt tgtcatcaag tttcacccct tacaaatata gataaagtct
     6301 gactttgtgc gcccccagaa aattggcgct gccgtacagc gttaccgccg aatgtgcggg
     6361 aatggtaacg ctgcgtggcc tttccagagg atgcatctcc agccctctgg cgtcatacca
     6421 gtaaaaacga taatgaacgg taacgggttc ttgcctttcg ttataaagcg ttgaggatgc
     6481 tgaaggttga atatcagacg tcgaaaggaa gggcttttct gcactgatgc ccgcagccaa
     6541 taaagatgac tccatcacca gcgattgctc atcattcacc ggaatttccg gatgtgaacg
     6601 acagcccacc agcagtaaca acaccagaga caccagccca aagcatcctt ttctcatcgt
     6661 tacagacctt tatgcgccag cattggtccc agcggacggc cacccaacaa gtgcatatgg
     6721 atgtggtaaa cctcttgtcc gccatggcgg ttggtattca tgatcagacg atagccatct
     6781 tcggcaatac cttcttgctc agcaattttt gccgctacgg tgatcatgcg tcccagcgcc
     6841 tgctcatgct cagctgagac gtcgttcaca gtcggaatga ggatattcgg aatgatcaga
     6901 atatgcgttg gcgcttgcgg cgaaatatcg cgaaacgccg ttaccagatc atcctggtag
     6961 acgatatcgg aggggatctc acgacgaata attttgctga atatagtttc ttctgccacg
     7021 acattttcct ttttcaaata gccatgcgtt gcgccatgct acgccgcgcc acactgcgag
     7081 tatagagtat ggtcgagtta aacctgctct ttcaacctta actcacgatt tcttaagcaa
     7141 aaaatcgttt tgctgccgta tatatcgcca ttattcccat ttctgcctgc gaatgcgctg
     7201 aaaagacatt ctctgtttgg tttacatgac aaatatgaat gcgtatattt ctcatttgca
     7261 tttacaaaca aaattattcg cacactaaat ataatcgctc atcaccctcc tccggcatga
     7321 gcctgacgac aacataaacc aagagatttc aaatgctttc aacacaattt aacagggata
     7381 atcaatatca agccatcacc aaaccgtcac tacttgccgg ttgcatagca ctggcactat
     7441 taccttctgc cgcttttgct gcaccagcca ctgaagaaac ggtgattgtt gagggttcag
     7501 ccacagctcc agatgatggc gaaaatgatt acagcgtaac gtctacctct gcgggtacca
     7561 aaatgcagat gactcaacgt gatattcctc agtcggtcac tattgttagc cagcagcgga
     7621 tggaagatca gcagttacaa acgctgggcg aagtgatgga aaacacgctg gggatcagca
     7681 aaagtcaggc ggattccgat cgtgctcttt attattcccg cggattccag atcgataact
     7741 atatggttga tggtatcccc acctattttg aatcgcgctg gaatctgggc gatgcacttt
     7801 ctgatatggc actctttgaa cgcgtagaag tagtgcgtgg cgcgacagga ctcatgaccg
     7861 ggacgggtaa tccatctgcg gcaattaata tggttcgaaa acacgcgacc agtcgtgaat
     7921 ttaaaggcga tgtctcggcg gaatacggta gctggaacaa agaacggtat gtggcggatt
     7981 tacaaagccc actcaccgaa gacggtaaaa tccgcgcgcg aattgtcggc ggctaccaga
     8041 ataacgactc atggctggac cgctacaaca gtgaaaagac cttcttctcg ggcattgtcg
     8101 atgctgattt aggcgatctt acgacgcttt cagccggtta cgaatatcag cgcattgatg
     8161 ttaatagccc tacctggggc ggtttaccgc gctggaatac tgatggcagc agcaacagtt
     8221 acgatcgcgc acgcagtacc gcacctgact gggcgtacaa cgataaagag atcaacaagg
     8281 tctttatgac cctgaagcag cagtttgctg atacctggca agcgacactg aatgccaccc
     8341 actctgaagt cgaatttgac agcaaaatga tgtatgtcga tgcctatgta aacaaagcgg
     8401 atggtatgct ggttgggcca tacagtaatt atggacctgg ctttgattat gtcggcggca
     8461 ccggttggaa cagtggcaaa cgtaaagttg atgcgctgga tttgttcgct gacggtagtt
     8521 atgaattgtt tggtcgtcag cacaatctaa tgtttggtgg cagttacagc aaacaaaaca
     8581 atcgttactt cagttcatgg gccaacatct tcccggatga aattggcagt ttctacaact
     8641 ttaatggcaa tttcccacaa accgactggt caccacagag cctggcgcag gacgatacca
     8701 cacatatgaa atcgttatat gctgccactc gtgtcaccct tgccgatccg ctgcatctga
     8761 tcctcggcgc acgttatacc aactggcggg ttgatacgct gacttacagc atggagaaaa
     8821 accacaccac gccttacgct ggtctggtgt ttgacatcaa tgacaactgg tcgacctacg
     8881 ccagctatac ctctattttc cagccgcaaa atgatcgtga cagttcaggc aaatatctgg
     8941 ctccaatcac cggtaacaac tacgagctgg gtctgaaatc ggactggatg aatagccgtc
     9001 tgaccaccac gttagccatc ttccgtattg agcaggataa tgtcgctcag tccaccggta
     9061 cacctatccc cggcagcaac ggcgaaaccg cctataaagc ggtggatggg acagtcagta
     9121 aaggggtgga atttgaactc aacggcgcaa ttaccgacaa ctggcagctg acatttggcg
     9181 caacgcgcta tattgcagag gataacgaag gaaacgccgt taatcctaat ctgccacgca
     9241 ccacggttaa aatgttcacc agctatcggt tgcctgtcat gccagagttg acggtcggcg
     9301 gtggtgttaa ctggcaaaat cgcgtgtata ccgacaccgt gacgccgtat ggcaccttcc
     9361 gcgccgagca aggtagctac gcgctggtgg atctcttcac ccgctaccag gtgacgaaaa
     9421 acttctcgtt acaggggaac gtcaataacc tgttcgacaa aacctacgat accaacgtgg
     9481 aaggttctat cgtctacggc acaccgcgta atttcagcat taccggcacg tatcaattct
     9541 gaataacacc tgtaaaaaag gcagccatct ggctgcctta gtctccccaa cgtcttacgg
     9601 attagtggtt acggatgtac tcatccatct cggttttcag gttatcggat ttagtaccga
     9661 aaatcgcctg aacaccagaa ccagcaacca ctacgcccgc tgcgcccagt ttcttcaggc
     9721 cggcctgatc cactttagac acatcagcaa cgctgacgcg cagacgggta atacatgcgt
     9781 cgaggttagt aatgttttct ttaccaccaa atgcagcaac cagagccggt gccatttcgc
     9841 tggtacctgt cgcttttgca tcttcagtcg cgtcttcacg acccggcgtt ttcagatcca
     9901 gtgctttaat cagcacgcgg aagatggtgt agtaaacaat cgcataaccg ataccgacga
     9961 tcgggaacag ccacagtttg ctgctgttac cagacagaac gatgaagtcg atcagaccgt
    10021 gcgagaacga cgtaccgtca cgcatcccca gaagaataca gattgggaat gccaggcctg
    10081 ccagaatcgc gtggatgatg tacaggatcg gcgcaacgaa catgaaggag aactcgatcg
    10141 gctcggtgat accggtcagg aacgaggtca gcgccgcgga gatcataata ccgcccactt
    10201 tcgcgcggtt ttctggttta gcagagtgcc agatagcaat tgcggcagct ggcagaccgt
    10261 acattttgaa caggaagcca ccagacagtt tacccgcagt cgggtcaccc gccatataac
    10321 gcggaatgtc gccgtggaaa acctgacctg ctgcgttggt gtattcacca atctgcatct
    10381 ggaaaggtac gttccagatg tggtgcagac caaacggtac caggcaacgt tcgatgaaac
    10441 cgtaaatgcc aaacgcaact accgggttct ggtaagcagc ccactgagag aaggtctgga
    10501 ttgcagaacc aatcggcggc caaatgaagg acagcacaac gccagtaaag atggcagcca
    10561 ggccagaaat gatcggcaca aagcgtttac cggcaaagaa gccaagatac tcaggcagct
    10621 taatacggta gaaacggtta aacatgtacg ctgcgatcgc accggagata atccctccga
    10681 gtacgccagt atccgccagg tgtttagagg cgatttcttc agcaggtaaa tgcagtacca
    10741 gtggcgcaac cacggccatg gttttaacca tgatgccata ggcaacaact gcggccagcg
    10801 cggatacgcc atcgttattg gtaaagccga gggcgacacc gatcgcaaaa atcagtggca
    10861 tgtttgcaaa gacggaaccg cctgcttctg ccataacatg cgatacaacg gcgggcagcc
    10921 agctgaaatt cgcggaaccg acgcccagca gaatacctgc gataggcagt acggataccg
    10981 gcagcatcag cgatttaccg accttttgca ggttagcaaa tgcattctta aacataattg
    11041 agagtgctcc tgagtatggg tgcttttttt acgttctcac gcgtggcaag gggggagagc
    11101 ctcgccgtgt acagggcatc taagcgccct ttatttatta cacagagtaa aataattcag
    11161 tgccaatttg tttgacggct atcacgtttc aacttcagat cattggagaa gttgcacatt
    11221 ttgacaaaac atatgtcaca atatttcaaa cgtggttatt caccgcccaa ttttcggcgg
    11281 tgaactttac tcgttttagc cattaattac gagctttaaa aaaactcatt caacggatgg
    11341 attgaaggcg ggaagcgtcg atgtgaaaca gacgggcgaa gttatcggtg gttacctgcg
    11401 ccagttcttc aacggcaaca cctttcaaca cagccatgta ttctgcaacg tcacgaacca
    11461 tcgcaggttg attctctttt cctcgatgcg gtaccggcgc aaggtaaggt gagtcagttt
    11521 ccaccagtaa ccgatccagg gggacataac gcgcagcatc gcgcagttgc tccgcattac
    11581 ggaaggtcac aatgccggaa aaggagatgt aaaatccgag atccagtaat ttacccgccg
    11641 tttctctgtc ctctgtaaaa cagtgtagta cgccaccgca atccgtcact ttttcttcgc
    11701 gcagaattgc cagcgtatcg gcacgggcgt cacgggtatg gacgataacc ggcttgttca
    11761 gttcacgacc aatctggata tgatggatga aggactcttg ctgacgtact ttagtttccg
    11821 gcgtgtaata ataatccagc ccggtttcac ccagcgctac aacaccctct tctgccgcca
    11881 gacggcgtaa atcttctaca tcgtagggat cattctggtt gagtggatgc acgccacaag
    11941 aaaatacgac gttgtcacgt tcgcctacca gatcccgcat atgtaaataa cccggtaatg
    12001 ttgtggcgac tgccagacaa aatttcacat cgcgtgcggc ggctttcgcc agaacgtcat
    12061 ccacgtcctt atgcaaagat tcataatcca gaccatcgag atggcagtgt gagtcgacta
    12121 aaaacatgat gtctctctta aagatgagga accggtagca caacgcccgg ttgcaggtaa
    12181 tgctcaatac gcagtaaaag atcggtgatg agaagctcgc ggttgatgcc tgtaacagac
    12241 attaactgtt cacgaatgtg gcaaacatcc cccagtatag cctgcaggcg cgagggagaa
    12301 agatggtttg ccagttcggc gaccaggccc ggcacatcaa cattggtcac ctgcgcagca
    12361 ccatgatggc gttttagcgc atccatcagc aacgttgcca gccagtgtaa acgcgccgga
    12421 gcttgttcat gattaagggc cgctagcagc gaataccagt cgcccgatgg cacgctatat
    12481 gccaacgcct gacacaatgt ttcacgagcc tgccagttat ctccctgaaa caacgccagt
    12541 gccgcgccag gcgaaccggc gcttaagcgc aatgcggcaa gtaatgcatc ctgtgacatt
    12601 gtcacttcgc gtgaaagcca ggtcacggcg tactgttccg gcggcggcgc aaggtaatgt
    12661 aaccgacaac gactacgtaa tgttgccagt aaacgttcag gctcgcgggt agccaggaaa
    12721 aaccaggttt ctgctggtgg ctcttcaagc gttttcagca atgcgttagc cgcggcgtcg
    12781 gttagtaagg cagcatcggt tacccaaacg actttcgcac cacctaagcg tgcgtgctca
    12841 ttcagctttt cggtgacctc acgtaccgca tcaacgccca gcgtattttt tcctttttcg
    12901 ggagccaggg tgtagtaatc gggatgcgtg ccagcctgca tcaactgaca tccacgacag
    12961 tgaccgcaac ttttgtggcc ctgcggttgt tggcagagta aataacgact cagggcgtag
    13021 attaaagcat catcgcccat gcccggtaac gcctgaatga gtagcgcatg gtgacctctt
    13081 ccggcctgat agctggctac cagtttttcg aaatcaggtc gtaaccatgg ataccatctc
    13141 atgcgtccaa ctccttcacc cagtgggtca cggtagtgcg gattgcatcc atcacggcct
    13201 ccagcggctg ggtggcatca atggtatgaa tgcttttatc ttgtgctgcc agttccagat
    13261 agcgggcgcg ggtgcgatta aagaaatcga aagattcttg ctcaatacga tccagctcgc
    13321 cgcgcgcacg cgcgcgtttt aagccaactt ccggggtaac atcgagatag agcgttaagt
    13381 cggggcgaaa atccccgaga acagcatcac gcagtgttgc cagcatatgt tggtcaatac
    13441 cacgtccgcc gccctgatac gcctgagtgg agagatcgtg gcgatcgcca atcacccagg
    13501 tgccgttagc cagagctggt ttgatgaccg tttctaccag ttgaacgcgc gcggcataaa
    13561 acatcagaac ttcggcttta tcggtaatga cttcatcgcc taccgatttg atatccagca
    13621 ccaggcttct taacttttcg gcaagttgcg taccgccagg ttcccgagtg aaaaccatgt
    13681 cgcggatacc cagttgctcg agcgtctcaa ccaccacatt acgcgcggta gttttgcctg
    13741 cgccttccag cccctcaatg acgatatact tactgcgcat ttttttcctt aagcactttc
    13801 agataatcct gcacagactt gttatgactg gcaagattgg tattaaacgt gtgaccacct
    13861 ttaccatcgg ccacaaaata gagatacggc gtttttgccg gatgcgcagc agccttcagc
    13921 gaatccgccc ccggcgtcgc tatcgcacct ggcggcagac cggtaatggt ataggtgtta
    13981 tacgctgtcg gcgtttccag gtctgcacga gaaagtttgc cattataacg ctctcccatc
    14041 ccgtaaatca cggtcgggtc ggtctgcagg cgcataccaa tgcgtaaacg gttgataaat
    14101 actgaggcaa ccttatcgcg ttcactggca acggcggttt ctttttcgat aattgatgcc
    14161 atcgtcacca actggttttt atctttataa ggcagaccgt ccgcacgccc ttcccaggcg
    14221 ctatcgaccg ctttcaccat tttcttgtgc gctcgcttga gtaacgcgac atcggtggta
    14281 ttggcggtat acatccaggt gtctggccag aaccaacctt caatccactc cgggttttcc
    14341 agttcaagtg cctgcgctac ggtggcgtac ttatcatcgc tcagcgtatg cttgatatac
    14401 ggggcctcac gcaattgctt gaggtaatcg ctcagacgca tcccttctac cagtcgcaga
    14461 gggaactgtg cttctttacc gctttccagc aatttcagca tctcgcgcac ggtcatctgc
    14521 ggtgtaaagc ggtaagtccc ggctttaaag tgagaaagat ccggttcgat acgcagcagc
    14581 cattgaaaaa cccgtggacg attgatgatc ttatcggcat aaagctgttc accgagcgcc
    14641 agacgtccgg tccctggctt cagggtaaat atcgtctctt ctttgataag caatttgctg
    14701 tcggcaagat ggcgaacctt ccagacgccc acaccagcgg cgatacccag taccaccagc
    14761 aataacaaga ttatcaataa cacttttttc atgactaatt cgggcgctca caaagtgggg
    14821 ctaaatattc atataacgtt gctgacgaaa aggagacatc gccacaggca catacgggca
    14881 tcactggcat taacgcatta caaataacca tctcatctgc ctgcaacgac tcttccagag
    14941 aggcttgcac ttcgacaagc tgataagagg attgtgccag caaacggata cagaattgtc
    15001 gcataatgcc gttaacacct gcctgatcca gtcgcggcgt ataaactacg ttgcccttcc
    15061 gccagaacaa attagccgca cagcattccg taacccaccc ttcgctgtca aggaccagcg
    15121 cctcatcagc gtttgtctgc tcaagatgag agcgaatcaa tacttgctca agacgattga
    15181 gatgtttaat acctgcaaga tgaggattgc gccccagccg caccgggctt agcgccaacg
    15241 taatcccctc gttacgcaaa cggtcgtaat gtgcaggata agccgtaacg gagagaatcc
    15301 gcgttgccgg tccgctgttc aatgtgctgt accctcgccc gccactaccg cgactgatca
    15361 cgactttcag cacaccattt tgctgttctg ctgccagcgt tttcatctct tgttcaagct
    15421 gaggccagaa gtcacaggaa atcatcaacc gctgacaagc atcctgtagt cgctggatat
    15481 gcgccgataa caaactgact ttaccgtcga taactctggc ggtggtaaaa caaccatcac
    15541 caaactgcgt tgcccgatcg cttactgcca gcgattcctg cttatgaccg ttaattaaga
    15601 acataccggc tccttatcag agaattgtta gtgtggcagc atgttcacta cggaacaagt
    15661 cggaataaaa gctaagaaaa aaggcccgca agcggacctt ttataagggt ggaaaatgac
    15721 aacttagatc tttttaaaga tcaaagaacc attagtgcca ccgaagccga aggagttaca
    15781 cagagtgtat tccattccgc taacctgacg cgcttcgtgc ggtacgaaat ccagatcgca
    15841 accttcatcc gggttatcca ggttgatggt tggcggaaca gcctgatcgc gcagcgccag
    15901 gatggagtag atagattcta ctgcacccgc cgcacctaac aggtgaccgg tcatagattt
    15961 cgtggagctt accaacacac ggcttgcagc ttcaccgaag atggttttca ccgcctgcgc
    16021 ttcagcttta tcgccagccg gcgtagaagt accgtgcgcg ttaacgtagc caatctgact
    16081 cgcttcaatg cctgcatcac gcagagcatt tgccatcgcc agagctgcgc ctgcgccatt
    16141 ttctggcggt gacgtcatat gataagcatc gctgctcata ccaaagccga cgagttcagc
    16201 gtaaattttc gcaccgcgtt ttttcgcgtg ttcgtactct tcaagtacca gcataccggc
    16261 accatcgccc agtacgaaac catcacgctc tttatcccac gggcggctcg ccgcttgcgg
    16321 gttatcattg cgggtagata atgcacgtgc cgcgccaaaa ccaccaacgc ccagcggcgt
    16381 actggctttc tctgcgccac ctgcaaccat cacgtcagca tcgccatacg cgataatacg
    16441 cgcagcatgg ccaatgttgt gcacgccgga agtacaggca gtcgcgatag agatgctcgg
    16501 gccacgcagg ccatacatga tagtcagatg acctgccacc atgttcacaa tcgttgacgg
    16561 aacgaagaat gggctgatct tacgtggacc accgttcatc agagatgtgt ggttttcttc
    16621 gatcagtccg aggccgccaa tcccggagcc aattgcggca ccaatgcggg ttgcgttctc
    16681 ttccgttatt tcaaggccag aatcctgcat ggcctgaacg ccagcgacaa ttccatattg
    16741 aatgaaggca tccatcttgc gctgttcttt gcgcgagata atgtcctcac agttaaaatc
    16801 ctttactaag ccagcaaatt tcgttgcata ggcgctagta tcgaaatggt cgattaggct
    16861 gatgccactc tgaccggcaa gcagagcttt ccaggtagac tctacggtat tgccgacagg
    16921 agacaacatg cccagtccgg tcacaactac acgacgctta gacacgtttg tcctccaggg
    16981 agggaaaaaa tgattctagt gggacaaaaa gataaaactc aggcggtcga acgaccgcct
    17041 ggagatgttc acttacgcct ggtggccgtt gatgtaatca atggcagcct gaacggtggt
    17101 gattttctca gcttcttcgt ccggaatctc agtatcaaac tcttcttcca gagccattac
    17161 cagctcaacg gtgtcaagag aatccgcgcc caggtcttca acgaaagaag cattgttggt
    17221 aacttcttcc tgcttaacgc ccagctgttc gccgataatt ttcttaacgc gttcttcgat
    17281 agtgctcata ctcttaaatt tcctatcaaa actcgctttc gcgatggttt tcgtagtgta
    17341 taaaatgttg aaaaatttgc aactaaatcc cggcaggtct taccacgatt ttacgttatt
    17401 ttgaggcctt accccccaat aacgcaaatc attttgcact aattattact cataaccacg
    17461 cagactgcgc gcaacatgag cattttgtgc aaatcgcggt cagaccatgt acatcccgcc
    17521 gttcacatgc aaagtttcac ccgtgatgta agctgcttcg tcggatgcca ggaatgcaac
    17581 cgcgttggcg atttcctgtg cgccgccgag gcgacccgca ggaacctgcg ccaggatacc
    17641 cgcacgctgg tcatcgctca gcgcacgtgt catgtccgtt tcaataaagc ccggagcaac
    17701 aacgtttaca gtaataccgc gtgacgcaac ttcgcgcgcc agtgatttac tgaagccgat
    17761 caagcccgct ttcgccgcag cgtagttggc ctgaccgcca tttcccatgg taccaaccac
    17821 agaaccgata gtgataatac gaccatgacg ctttttcatc atagcgcgca ttaccgcttt
    17881 tgacagacgg aaaacagatg aaaggttggt ttcgataata tcgttccact cttcatcttt
    17941 cattcgcatt aacaggttat cacgagtgat accggcatta ttgaccagga tatccacttc
    18001 accaaattct gcgcgaattt tttccagaac agattcgata gatgccgggt cggtcacatt
    18061 caacatcaga cctttgccgt tggcacctaa ataatcactg atcgcctgag cgccattttc
    18121 actggtcgca gtgccaataa ctttcgcgcc acgggctgcg agcgtttcag caattgcgcg
    18181 gccaattccg cggcttgcac cggttaccag tgcgattttt ccttcaaaat tcatgatttt
    18241 cctcttttaa agctcgagcg ccgctgccat cgctgaaggt tcgttcagcg ccgaggcggt
    18301 cagggtgtcg acaatgcgtt tcgtcaggcc agtaagcact ttgcccgggc cgacttcata
    18361 gagatgttct acgccttgcg ctgccatgta ctcaacagac ttcgtccact gaaccgggtt
    18421 atacaactga cgtaccagtg cgtcacggat ggcatcacca ttggtttcgc atttcacatc
    18481 aacgttattc acaacaggaa ctgttggtgc gttaaaggtg attttcgcta attctactgc
    18541 cagtttgtcg gctgctggtt tcatcagcgc acagtgagac ggtacgctca ctggtaacgg
    18601 cagcgcgcgt tttgcgcccg ccgctttaca ggcagcgcca gcacgctcaa ccgcttcttt
    18661 atgaccggca ataaccacct gtcccggaga gttaaagttt accggagaaa cgacctgacc
    18721 ttctgcagct tcttcacacg ctttcgcaat agacgcatca tccagaccga tgattgccgc
    18781 catagcgccc gtgccttccg gtacggcttc ttgcatgaac ttgccgcgca tctcaaccag
    18841 acgcaccgca tcagcgaaat caatcacacc agcgcaaacc agcgcggagt attcccccag
    18901 gctgtgaccg gccatcattg ccggtgcttt accgccctgc tgctgccata cgcgatacag
    18961 cgcaacagat gcagtcaaca gcgcaggctg agtttgccag gttttattca gttcttcagc
    19021 tggcccctgc tgggtcagcg cccacaggtc gtagcccagc gccgcagaag cttcagcaaa
    19081 cgtttcttcg acaattggat agctcgccgc catatcagcc agcattccaa cggtttgaga
    19141 accctgtcca gggaacacaa atgcaaattg cgtcatgttt taatccttat cctagaaacg
    19201 aaccagcgcg gagccccagg tgaatccacc gccaaaggct tcaagcagaa ccaactgccc
    19261 cggcttaatg cgcccgtcgc gtacagcttc atccagcgcg cacgggacag aggccgcaga
    19321 ggtattaccg tggcgatcca gcgtcaccac gacattatcc atagacatac cgagtttttt
    19381 cgccgttgca ctgataatac gcaggttagc ctgatgcgga accagccagt ccagttgaga
    19441 acggtcaaga ttattcgccg ccagcgtctc atcaacgatg tgcgccagtt ccgttaccgc
    19501 aaccttgaag acttcgttgc ccgccatcgt cagatgaatt gaattctctg gattcacgcg
    19561 gtcggcgttt ggcagcgtca gcaattcacc ataactaccg tcggcatgca gatgggtgga
    19621 aatgattccc ggctcttcag aggcagccag caccgcagcg cccgcgccat cgccaaaaat
    19681 aataatagtc ccacgatcgg ttggatcgca ggtgcgcgcc agtacatcgg aaccgacgac
    19741 cagagcatac ttcaccgccc cagatttcac gtattgatcg gctacgctta atgcataggt
    19801 gaaacctgcg caggctgctg caacgtcaaa tgccgggcaa cctttaatgc ccaacatgct
    19861 ttgaatctga caagctgcgc tcgggaaagc gtgcgtagca gaagtcgttg ccacaacgat
    19921 caggccaatc tggtctttct caatgcccgc catctcaatt gcgcgtgtcg ccgcttcaaa
    19981 gcccatggtt gaaacggttt cgtttggcgc ggcaatgtgg cgttcgcgga taccggtacg
    20041 agtgacaatc cactcgtcag aggtgtccac cattttttcc aaatcggcgt ttgtccgcac
    20101 ttgttcgggc agatagctgc cagtaccaat aatcttcgta tacatgtacg ctcagtcact
    20161 tttcggttat ataccgtcac ttgcaaactg cgagttcgct ggcagcgtcc tgctaccgca
    20221 gagttccgct tttgccaccg tccagcagct caaaaccagc tgggtataca gattccaggc
    20281 gagcggcaat tcgctgagga acttgtcgct gcaccgcctg cactgcctgt tcaatcgcga
    20341 ccgcaaaagc tcgctgattg gctgcaccat gactttttat caccgtgccg cgcaatccta
    20401 acagacaggc gccgttatac tggtcggggt tgaggtgact gaatcgcctc gtcaggctct
    20461 tttgtagcca acgctttaat aacagtagcc accacgaccg ttttttccct tcaccctgag
    20521 atttcagcag agaaaggaac atcctgacaa caccttccat cgtctttaat gtgacatttc
    20581 ctgtaaagcc gtcacaaacc agcacatctg tcttgccagt taacaactca ttggcttcaa
    20641 gatagccgat ataattgata gaagggattg ttttaagcac cgctgaggca tcccgaatac
    20701 tgtcgagacc ctttacttct tcttcaccaa tattgagcaa cgccacgcga ggattgggaa
    20761 tttccaccac ctcttcagcc agaactgagc ccataatggc aaattgcacc agcattgtgc
    20821 tgtcacaatc gacgttggcc cctaagtcaa ggaccaccgt tttgcccttt tgctgatgtg
    20881 gtaataccgt caccagcgcc ggacgctcaa tcccctccag gggcttgagt aataattttg
    20941 ccagccccat cagcgccccg gtattaccgg cactgacaca ggcttgcgct cgaccttctt
    21001 tcaccagctc cagggccacg cgcattgaac tcccacgact ggcgcggata gcttgcgaag
    21061 gccgggcatc actggcgata actgactgcg caggaataat ctgcagacgc gaacgttgtt
    21121 caaagtcagc tttagcaagt aatggcgtga tggcgtcggg attgccgact aaaagaagag
    21181 tgagttgcga attagaattc agtgcctgca atgctgcagg cactgtcacg gaagggccaa
    21241 aatcccctcc catgacatct aacgccaggg ttagacgtgt caaggtatcg tcgccgcccg
    21301 gtttggtctt tccccagttg cctggggaaa atcctcacta agcttcatca cgcagatgcg
    21361 tgattactta gcgatgacct tgcggccgcg gtagtaaccg tcggcagtga tgtggtgacg
    21421 caggtgtttt tcaccagaag ttttgtctac agacaggctg gtgactgcgg tcagcgcgtc
    21481 atgggaacga cgcatgccac gtttggaacg ggttggttta ttctgttgta cggccatgga
    21541 ccttactcct caattacggt ttatccccga tccaacgggg agcaccaatt acttacgctt
    21601 taagctggct aatacggcaa atgggtttgg cttttgcgct tcttcaggca gttcaccaaa
    21661 gaccatgtcc gcttcggaca cttcacagtg ttcagaatca tgcaccggaa ctaccggcaa
    21721 ggcgaggatg atttcatctt caaccattgc aagcagatcg atttcaccga attcgttaac
    21781 ctcaatcggt tcatacgctt ccggcagtgc ttcagcctgt tcgtctgaac gcacaggact
    21841 aaaacaatac gttgtgtaga cctgatgagt aaacggcttc ccgcaacgct gacactcgag
    21901 cgttaccgtc accttcgcat cgccgtttaa cactgcgaga cgttggttat cgatagcgaa
    21961 cgacatggag cattccacat cactgtccac actgactacg gattcggcga cgcgctcaac
    22021 ctgatcaggg gtatagatac cctggtaatc aaggcgtttt tgagccgtac gaaccggatc
    22081 gagagtcagg ggtaatttta ccttttgcat agggcgcgca tattaacttt gtaacgtcat
    22141 agagtcaaag aaaaaggcag cctgtggttg ccttttgcca ataattcgca cacattgcgg
    22201 gttactgctt tattttcgtt cagtgctgat aacaaacatc aacctgcaaa acgaagcgca
    22261 tagtttaaaa tggctatcat caatacgcta tatctgatgg aaaaaaatat gcctaaactt
    22321 attttagcct ccacctcgcc atggcgtcgc gctcttctgg aaaaactgca aatctctttt
    22381 gaatgtgcag caccagaggt cgacgaaacc ccacgcagcg acgaatcacc gcgacagttg
    22441 gtgcttcgac tggcacaaga aaaagcgcaa tctctggcgt cacgttatcc ggatcattta
    22501 attattggtt cagaccaggt atgtgttctt gatggcgaaa tcaccggtaa accgttaacg
    22561 gaagaaaatg cccgtctgca attacgcaaa gccagcggca atatcgtcac cttctatact
    22621 ggactggcgt tgtttaattc ggcgaatggg catctgcaaa cagaagtgga gccttttgac
    22681 gtccatttcc gtcacctgag cgaggcggag attgataatt acgtgcgtaa agagcatccc
    22741 ctgcactgcg cgggtagctt taagagtgaa ggatttggca ttacgctgtt tgagcgttta
    22801 gaggggcgtg atcctaacac gctggttggt ttaccgctaa tcgcgctgtg tcagatgtta
    22861 cgtcgggaag ggaaaaaccc gctgatggga tagttttttg cgccggatgt ggttacgtcg
    22921 catccggcaa tcggtgctgg cggcctgatg cggcgtaaac gccttatcag gccaaccgcc
    22981 cattatcagg tttatatgct tgtattagcg cgcgttacgc agcttttgca aacaacgctt
    23041 caaaccttca tccatcggag cttcgatacg catcacctca ccggtccccg gatgagtaaa
    23101 cttcaacgct gcagcgtgca ggaacaggcg atttaatccc gtgcctgctt cagtgagctg
    23161 cctgtcaaat tcacggtcac cgtagcgatc gtcaaaggca atcggatgac ccgcatattg
    23221 tgtatgcaca cggatctggt gagtacgccc tgttaccggg ctacaacgca ccagggtggc
    23281 aaatgcatag cgttcttcca ctttaaagcg tgtttccgac ggtttgcctt cctgactcac
    23341 acgcacgata cgttcgccgc tttgcagaat atttttcagt aacggtgctt gaacgctctt
    23401 cacatgcgac tgccactgac cgcgcaccag cgccaggtaa tctttttgca tccctttttc
    23461 acgtaattgc tcatgcagag aacgcaacgc cgagcgtttt ttcgctacca gcaaaacacc
    23521 tgaggtgtcc cggtcaagac gatgaaccag ttcaaggaac cgcgcttccg ggcgcaacgc
    23581 ccgcaaacct tcaataacgc cgaagcttaa accactgccg ccatgtaccg ccgtaccgga
    23641 aggtttattc agcaccagga tgtgatcatc ttcatataag atgacgtccg ccagcgccgc
    23701 caccttttgc agatgtggcg aaaccgcctc ttcttcccgc tcagcaacgc gaaccggtgg
    23761 aatacgcacc tcatcacccg cttcgagttt atattcaggc ttaatacgtt ttttgttcac
    23821 ccgcacttcg cctttacgca aaatacggta aatcatactt tttggtacgc ctttcaattg
    23881 ggtacgcaaa aagttatcga tacgttgccc cgcttcgtca gcggtgatag caacaatttt
    23941 tacggatgga gtctctgttt tcatggttgg cgattctaat tagccaacag gattcgcgcc
    24001 actcattttt ctatgcttat
//
LOCUS       DACAOP010000070        23941 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.070, whole genome shotgun sequence.
ACCESSION   DACAOP010000070 DACAOP010000000
VERSION     DACAOP010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23941
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.070"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..344
                     /locus_tag="IT892_003030"
     CDS             <1..344
                     /locus_tag="IT892_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP3136221.1"
                     /translation="NNYREKITLEQLSKKFRASVSYICHEFTKEYRISPINYVIQRRM
                     TEAKWSLTNTELSQAEISWRVGYENVDHFAKLFLRHVGCSPSDYRRQFKNCFAEQEIL
                     SEFPQPVSLVG"
     gene            complement(387..1538)
                     /locus_tag="IT892_003031"
     CDS             complement(387..1538)
                     /locus_tag="IT892_003031"
                     /EC_number="1.3.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HAP3136222.1"
                     /translation="MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMR
                     ALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSA
                     EQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
                     EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEV
                     EESDMVGEEGMGFLNVMYNFEMERLINAARSTGFAECAFEDAARYANQRIAFGKPIGH
                     NQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKLYCARTAMEVIDDAI
                     QIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK"
     gene            complement(1552..3147)
                     /locus_tag="IT892_003032"
     CDS             complement(1552..3147)
                     /locus_tag="IT892_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate CoA-transferase YdiF"
                     /protein_id="HAP3136223.1"
                     /translation="MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEAT
                     TLITALADKYKQTQTPRNLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRI
                     SELAEQNKIIAYNYPQGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKE
                     DLIKLVEFDNKEYLYYKAIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNN
                     GGIVMMQVQKMVKKATLHPKSVRIPGYLVDIVVVDPDQTQLYGGAPVNRFISGDFTLD
                     DSTKLSLPLNQRKLVARRALFEMRKGAVGNVGVGIADGIGLVAREEGCADDFILTVET
                     GPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKF
                     NGKIMGTGGFIDISATSKKIIFCGTLTAGSLKTEITDGKLNIVQEGRVKKFIRELPEI
                     TFSGKIALERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDILDKMDFTPVISPE
                     LKLMDERLFIDAAMGFVLPEAAH"
     gene            complement(3290..4048)
                     /gene="aroD"
                     /locus_tag="IT892_003033"
     CDS             complement(3290..4048)
                     /gene="aroD"
                     /locus_tag="IT892_003033"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAP3136224.1"
                     /translation="MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDI
                     LEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNR
                     AAIDCGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRK
                     MQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEV
                     FGSAATFGAVKKASAPGQISVNDLRTVLTILHQA"
     gene            complement(4079..4945)
                     /gene="ydiB"
                     /locus_tag="IT892_003034"
     CDS             complement(4079..4945)
                     /gene="ydiB"
                     /locus_tag="IT892_003034"
                     /EC_number="1.1.1.282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinate/shikimate dehydrogenase"
                     /protein_id="HAP3136225.1"
                     /translation="MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEV
                     DNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLR
                     GYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEF
                     FDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVN
                     DISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFP
                     LEYVKQVMGFGA"
     gene            complement(4957..6222)
                     /locus_tag="IT892_003035"
     CDS             complement(4957..6222)
                     /locus_tag="IT892_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416206.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136226.1"
                     /translation="MSQNKAFSTPFILAVLCIYFSYFLHGISVITLAQNMSSLAEKFS
                     TDNAGIAYLISGIGLGRLISILFFGVISDKFGRRAVILMAVIMYLLFFFGIPACPNLT
                     LAYGLAVCVGIANSALDTGGYPALMECFPKASGSAVILVKAMVSFGQMFYPMLVSYML
                     LNNIWYGYGLIIPGILFVLITLMLLKSKFPSQLVDASVTNELPQMNSKPLVWLEGVSS
                     VLFGVAAFSTFYVIVVWMPKYAMAFAGMSEAEALKTISYYSMGSLVCVFIFAALLKKM
                     VRPIWANVFNSALATITAAIIYLYPSPLVCNAGAFVIGFSAAGGILQLGVSVMSEFFP
                     KSKAKVTSIYMMMGGLANFVIPLITGYLSNIGLQYIIVLDFTFALLALITAIIVFIRY
                     YRVFIIPENDVRFGERKFCTRLNTIKHRG"
     gene            complement(6449..7663)
                     /locus_tag="IT892_003036"
     CDS             complement(6449..7663)
                     /locus_tag="IT892_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136227.1"
                     /translation="MKNPYFPTALGLYFNYLVHGMGVLLMSLNMASLETLWQTNAAGV
                     SIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFGILQTNNIIIAYVFG
                     FLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWF
                     GWSFMIAAGIMFINALFLYRCTFPPHPGRRLPVIKKTTSSTEHRCSIIDLASYTLYGY
                     ISMATFYLVSQWLAQYGQFVAGMSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTT
                     LLMLYTFISFIALFTVCLHPTFYVVIIFAFVIGFTSAGGVVQIGLTLMAERFPYAKGK
                     ATGIYYSAGSIATFTIPLITAHLSQRSIADIMWFDTAIAAIGFLLALFIGLRSRKKTR
                     HHSLKENVAPGG"
     gene            complement(7763..8119)
                     /locus_tag="IT892_003037"
     CDS             complement(7763..8119)
                     /locus_tag="IT892_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416204.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiL family protein"
                     /protein_id="HAP3136228.1"
                     /translation="MNAYELQALRHIFAMTIDECATWIAQTGDSESWRQWENGKCAIP
                     DRVVEQLLAMRQQRKKHLHAIIEKINNRIGNNTMRFFPDLTAFQRVYPDGNFIDWKIY
                     QSVAAELYAHDLERLC"
     gene            complement(8255..8362)
                     /gene="rprA"
                     /locus_tag="IT892_003038"
     ncRNA           complement(8255..8362)
                     /ncRNA_class="antisense_RNA"
                     /gene="rprA"
                     /locus_tag="IT892_003038"
                     /product="antisense sRNA RprA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00034"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00034"
     gene            complement(8548..9660)
                     /gene="ydiK"
                     /locus_tag="IT892_003039"
     CDS             complement(8548..9660)
                     /gene="ydiK"
                     /locus_tag="IT892_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter YdiK"
                     /protein_id="HAP3136229.1"
                     /translation="MVNVRQPRDVAQILLSVLFLAIMIVACLWIVQPFILGFAWAGTV
                     VIATWPVLLRLQKIMFGRRSLAVLVMTLLLVMVFIIPIALLVNSIVDGSGPLIKAISS
                     GDMTLPDLAWLNTIPVIGAKLYAGWHNLLDMGGTAIMAKVRPYIGTTTTWFVGQAAHI
                     GRFMVHCALMLLFSALLYWRGEQVAQGIRHFATRLAGVRGDAAVLLAAQAIRAVALGV
                     VVTALVQAVLGGIGLAVSGVPYATLLTVLMILSCLVQLGPLPVLIPAIIWLYWTGDTT
                     WGTVLLVWSGVVGTLDNVIRPMLIRMGADLPLILILSGVIGGLIAFGMIGLFIGPVLL
                     AVSWRLFAAWVEEVPPPTDQPEEILEELGEIEKPNK"
     gene            10049..13105
                     /locus_tag="IT892_003040"
     CDS             10049..13105
                     /locus_tag="IT892_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAP3136230.1"
                     /translation="MIPQISQAPGVVQLVLNFLQELEQQGFTGDTATSYADRLTMSTD
                     NSIYQLLPDAVVFPRSTADVALIARLAAQERYSSLIFTPRGGGTGTNGQALNQGIIVD
                     MSRHMNRIIEINPEEGWVRVEAGVIKDQLNQYLKPFGYFFAPELSTSNRATLGGMINT
                     DASGQGSLVYGKTSDHVLGVRAVLLGGDILDTQPLPVELAETLGKSNTTIGRIYNTVY
                     QRCRQQRQLIIDNFPKLNRFLTGYDLRHVFNDEMTEFDLTRILTGSEGTLAFITEARL
                     DITRLPKVRRLVNVKYDSFDSALRNAPFMVEARALSVETVDSKVLNLAREDIVWHSVS
                     ELITDVPDQEMLGLNIVEFAGDDEALIDERVNALCARLDELIASHQAGVIGWQVCREL
                     AGVERIYAMRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDSHGLSY
                     GMFGHVDAGVLHVRPALDMCDPQQEILMKQISDDVVALTAKYGGLLWGEHGKGFRAEY
                     SPAFFGEELFAELRKVKAAFDPHNRLNPGKICPPEGLDAPMMKVDAVKRGTFDRQIPI
                     AVRQQWRGAMECNGNGLCFNFDARSPMCPSMKITQNRIHSPKGRATLVREWLRLLADR
                     GVDPLKLEQELPESGVSLRTLIARTRNSWHANKGEYDFSHEVKEAMSGCLACKACSTQ
                     CPIKIDVPEFRSRFLQLYHTRYLRPLRDHLVATVESYAPLMARAPKTFNFFINQPLVR
                     KLSEKHIGMVDLPLLSVPSLQQQMVGHRSANMTLEQLESLNAEQKARTVLVVQDPFTS
                     YYDAQVVADFVRLVEKLGFQPVLLPFSPNGKAQHIKGFLNRFAKTAKKTADFLNRMAK
                     LGMPMVGVDPALVLCYRDEYKLALGEERGEFNVLLANEWLASALESQPVATVSGESWY
                     FFGHCTEVTALPGAPAQWAAIFARFGAKLENVSVGCCGMAGTYGHEAKNHENSLGIYE
                     LSWHQAMQRLPRNRCLATGYSCRSQVKRVEGTGVRHPVQALLEIIK"
     gene            13102..13512
                     /gene="menI"
                     /locus_tag="IT892_003041"
     CDS             13102..13512
                     /gene="menI"
                     /locus_tag="IT892_003041"
                     /EC_number="3.1.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
                     /protein_id="HAP3136231.1"
                     /translation="MIWKRKITLEALNAMGEGNMVGFLDIRFEHIGDDTLEATMPVDS
                     RTKQPFGLLHGGASVVLAESIGSVAGYLCTEGEQKVVGLEINANHVRSAREGRVRGVC
                     KPLHLGSRHQVWQIEIFDEKGRLCCSSRLTTAIL"
     gene            13612..13800
                     /locus_tag="IT892_003042"
     CDS             13612..13800
                     /locus_tag="IT892_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136232.1"
                     /translation="MSTQLDPTQLAIEFLRRDQSNLSPAQYLKRLKQLELEFADLLTL
                     SSAELKEEIYFAWRLGVH"
     gene            14348..14716
                     /gene="sufA"
                     /locus_tag="IT892_003043"
     CDS             14348..14716
                     /gene="sufA"
                     /locus_tag="IT892_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold SufA"
                     /protein_id="HAP3136233.1"
                     /translation="MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLG
                     VKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQI
                     FKFHNPKAQNECGCGESFGV"
     gene            14725..16212
                     /gene="sufB"
                     /locus_tag="IT892_003044"
     CDS             14725..16212
                     /gene="sufB"
                     /locus_tag="IT892_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416198.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAP3136234.1"
                     /translation="MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVR
                     AISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDT
                     CASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
                     EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCP
                     MELSTYFRINAEKTGQFERTILVADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKN
                     AEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCIL
                     RGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKI
                     MPTATNARNFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQ
                     RGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG"
     gene            16222..16968
                     /gene="sufC"
                     /locus_tag="IT892_003045"
     CDS             16222..16968
                     /gene="sufC"
                     /locus_tag="IT892_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAP3136235.1"
                     /translation="MLSIKDLHVSVEDKAILRGLSLDVHPGEVHAIMGPNGSGKSTLS
                     ATLAGREDYEVTGGTVEFKGKDLLALSPEDRAGEGIFMAFQYPVEIPGVSNQFFLQTA
                     LNAVRSYRGQETLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
                     VLEPELCILDESDSGLDIDALKVVADGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHV
                     LYQGRIVKSGDFTLVKQLEEQGYGWLTEQQ"
     gene            16943..18214
                     /gene="sufD"
                     /locus_tag="IT892_003046"
     CDS             16943..18214
                     /gene="sufD"
                     /locus_tag="IT892_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAP3136236.1"
                     /translation="MAGLPNSSNALQQWHHLFEAEGTKRSPQAQQHLQQLLRTGLPTR
                     KHENWKYTPLEGLINSQFVSIAGEISPQQRDALALTLDSVRLVFVDGRYVPALSDATE
                     GSGYEVSINDDRQGLPDAIQAEVFLHLTESLAQSVTHIAVKRGQRPAKPLLLMHITQG
                     VAGEEVNTAHYRHHLDLAEGAEATVIEHFVSLNDARHFTGARFTINVAANAHLQHIKL
                     AFENPLSHHFAHNDLLLAEDATAFSHSFLLGGAVLRHNTSTQLNGENSTLRINSLAMP
                     VKNEVCDTRTWLEHNKGFCNSRQLHKTIVSDKGRAVFNGLINVAQHAIKTDGQMTNNN
                     LLMGKLAEVDTKPQLEIYADDVKCSHGATVGRIDDEQIFYLRSRGINQQDAQQMIIYA
                     FAAELTEALRDEGLKQQVLARIGQRLPGGAR"
     gene            18211..19431
                     /gene="sufS"
                     /locus_tag="IT892_003047"
     CDS             18211..19431
                     /gene="sufS"
                     /locus_tag="IT892_003047"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase SufS"
                     /protein_id="HAP3136237.1"
                     /translation="MIFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEA
                     EFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVA
                     NSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTL
                     FDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCD
                     FYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEA
                     GTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGV
                     IAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVD
                     RLVTGLQRIHRLLG"
     gene            19444..19860
                     /gene="sufE"
                     /locus_tag="IT892_003048"
     CDS             19444..19860
                     /gene="sufE"
                     /locus_tag="IT892_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfuration protein SufE"
                     /protein_id="HAP3136238.1"
                     /translation="MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDRSP
                     QNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDV
                     RPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS"
     gene            20009..21013
                     /gene="ldtE"
                     /locus_tag="IT892_003049"
     CDS             20009..21013
                     /gene="ldtE"
                     /locus_tag="IT892_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtE"
                     /protein_id="HAP3136239.1"
                     /translation="MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTV
                     QEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGTTITIPSQLLLPDAPRQGIIVNL
                     AELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLER
                     GIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIK
                     ALFSSVRTGTPVKVINEPVKYSVEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQ
                     FKDNKAVDQKLVDKALYRRAGYPVSVSSGATPAASNAPSVESAQNGEPEQGNMLRVTQ
                     "
     gene            complement(21077..21313)
                     /locus_tag="IT892_003050"
     CDS             complement(21077..21313)
                     /locus_tag="IT892_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006675846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major outer membrane lipoprotein"
                     /protein_id="HAP3136240.1"
                     /translation="MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQL
                     SNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK"
     gene            complement(21624..23036)
                     /locus_tag="IT892_003051"
     CDS             complement(21624..23036)
                     /locus_tag="IT892_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase I"
                     /protein_id="HAP3136241.1"
                     /translation="MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHG
                     QRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGN
                     SEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
                     PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHII
                     SKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVIT
                     ATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER
                     TDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFP
                     DATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVV
                     MVSGALVPSGTTNTASVHVL"
     gene            23593..23802
                     /gene="fumD"
                     /locus_tag="IT892_003052"
     CDS             23593..23802
                     /gene="fumD"
                     /locus_tag="IT892_003052"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase FumD"
                     /protein_id="HAP3136242.1"
                     /translation="MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTA
                     LANKRIQRSELEKQAMETVINALVK"
BASE COUNT         6249 a         5745 c         6022 g         5925 t
ORIGIN      
        1 ataataatta tcgcgaaaaa atcactttag aacagttatc gaaaaaattt cgtgccagcg
       61 tcagttatat ttgccatgaa tttaccaaag agtatcgtat ttcccctatt aactatgtta
      121 ttcaacggcg tatgacggaa gcaaaatggt cactcactaa tactgaatta tcacaggcag
      181 agatctcctg gcgtgtgggt tatgaaaatg tcgatcactt tgccaaactg tttttgcgcc
      241 atgtcggttg ttcgcccagc gattaccgta gacaatttaa aaactgtttt gcggaacaag
      301 aaatcctatc tgaatttcct caaccggtaa gtcttgttgg ataaatctgg cggcgcagtt
      361 tgttaagaag ctgcgccgcc tgcagattat ttgttctgat agtctttcag gatctgccga
      421 cctgctacgt aaatcataat ttcgtctgta ccgccgccga tacgttcaca acggacatca
      481 cgccagaagc gggagacgcg cgcctcatcg gtatagccca gaccgcccat gatttgaatc
      541 gcatcatcaa tgacttccat tgcggtacgt gcacagtaca gttttgccag cgccgcgctg
      601 gtgcgcagtg actgatgctg atcggcttgc catgccactt tcagcaccat gttgcgcatg
      661 ttgtcgatct taatcgccat cagcgccagt ttttcctgga tcatctggtt atgaccaatg
      721 ggcttaccaa aagcgatacg ttggttggca tagcgggcgg catcttcaaa ggcgcattcg
      781 gcaaagccgg tgctgcgcgc ggcgttgatc aggcgctcca tctcaaagtt gtacatcaca
      841 ttgaggaaac ccattccttc ttcgcccacc atgtcgctct cttcaacctc cacgttgtcg
      901 agatagactt cgcaggtgct gagcatatgc cagccgattt tatgcagcgg gttaatctta
      961 atgccgggct tactggagtc gacccaccac agggtgaagg cttttttggg atctttcggt
     1021 tgcggatcgc gcgccagcac cagcatatac gggtactctt tcgcaccggt aataaaggtt
     1081 ttttgtccgt tgatgtagac cttgccgttt ttacgcgtgt aagtggtagt ggcactgttg
     1141 ttatctgagc cagcacctgg ttccgtcaac gccagggcat aggcgggatc acccgtttcc
     1201 agggtgctct ctgccgtttt acgtagctgc tctgcagaac cgaaacggcg catactgtga
     1261 atacattgac cgttggtaat taaaaatgcc ggagcaccgc attttgacac ttccatcagc
     1321 gccagcattt gggtgacgta atccgcaggg ataccaccaa attcttccgg cacgccaagc
     1381 atggaaatac cgttatccgc cagcgcccgc ataaactcac gcggatatgt cccgttttga
     1441 tcgcaggtgc ggaaatactc ttccggaaag ttagtcgtaa tcagttcgcg aatactggcc
     1501 agcagcagtt cttgttcttc agttaaagaa aaatccatca ttatactcct gttaatgagc
     1561 cgcttcaggc aggacaaaac ccatcgccgc atcgataaat aatctttcgt ccatcagttt
     1621 gagttctggc gaaatcactg gggtgaaatc cattttgtcg agaatatctt tttgtaaatc
     1681 gacgccaggg gcgatttcga ttaaatgcag gccgtcttct ttcagcgtga atactgcgcg
     1741 ctcagtgata taacgaacat ccagccctcg ctcgagagcg atttttccgc tgaaagtaat
     1801 ttccggtagt tcccgaataa atttcttcac ccgtccttcc tggacgatat ttaatttgcc
     1861 gtcggtaatt tctgttttta aactgcccgc agttaatgtg ccgcagaaaa tgattttctt
     1921 cgaagtggca ctgatatcaa taaatccacc ggtgcccatg attttaccat tgaatttatg
     1981 cacgccgacg ttaccgtgct ggtcgacttc agcaaaactc aaataacaaa catccagacc
     2041 gccaccgtga taaaaatcaa actgggacgt catatccaga atggcacggg tattcacgtt
     2101 cgcgccaaag gcgatcccct gtgaagtaat tccgccaatc ggacctgttt ctaccgtcag
     2161 aataaagtca tcagcacaac cttcttctcg ggcgaccagg ccaatgccgt cagcaatacc
     2221 gacgccgaca ttccccaccg cgcctttacg catttcgaat aatgcgcgcc gcgcaactaa
     2281 tttacgttgg tttaggggca ggctaagttt ggtactgtca tcaagggtga agtcaccaga
     2341 aataaagcgg ttaaccggtg caccgccata cagttgggtt tgatccggat cgaccaccac
     2401 aatatccacc agataacccg gaatacggac agatttagga tgcagcgtgg ctttcttaac
     2461 cattttctgc acctgcatca tcacaatacc gccgttattg tgcaccgcct gggcaataac
     2521 caatgcgtcg agatacatca cctcatcttc aaaagtggcg tagccttcac tgtcgcaggt
     2581 ggtagcgcga atgaaggcaa tatctggcgc aatcgctttg taatagagat attctttgtt
     2641 atcaaactcg accagtttaa tcaggtcttc tttagtgact tcattcagtt tgccgccttg
     2701 ctggcgtgga tcgacaaatg tcccgatgcc aatatcacta ataataccag gctggtgggc
     2761 tgcggcggcg cgtaaggttt gtgtaagtac accttgtggg tagttataag caataatttt
     2821 attttgttct gcgagttcag aaatacgcgg cgattgtccc cagtgaccac ataatgccca
     2881 tttcaccaga ccttcttgcg ccagaggact aataccacgg tcggcgcgat cgccaagccc
     2941 tgttggacta ataatcgata aattacgtgg tgtttgagtc tgtttatatt tatcagcaag
     3001 agcagtaatt aacgtggtgg cttccagaat accgccgcca gcgcctaaca cacaaagtgt
     3061 tgcttcgtcg ggaatataat tcaccgcttc ctgtgccgac aggaccggca ctcgtccatt
     3121 aatacgaggt ggttttacag gtttcattgt taattcctga ttcagatgtg attttcccta
     3181 cgtcaaatgg agaattagcg cacagagact cacgaaatat ttttattaaa tacgattgaa
     3241 tatatttttt agttcggcgg ggagggtgtt cccgccgaaa tattattgct tatgcctggt
     3301 gtaaaatagt taataccgtg cgcaaatcat ttaccgagat ttgccctggc gcagacgctt
     3361 tttttaccgc accaaaagtt gccgccgagc caaatacttc accagccaga cgagaaatta
     3421 cgccagtttt tgccatcgac atcgtgataa ttggacgatc ggcatactgc tcctgcatct
     3481 ccagggtcgc ggcaagcaac gtcagcacat cgctggtact ttgcggcatc agcgcaatct
     3541 taggaatatc ggcgtcgaag gattgcattt tgcgcagacg ggcaatgatt tcttcggctt
     3601 ccggcgtttt atggaagtca tggttggaca tgactacttt cacatcatgc gcgtgggcgt
     3661 aggcgacggt ttctttaacc tgatcatcac cggtaaataa ctccagatcg atcatatcaa
     3721 ccaggccgca gtcgatggct gcacgattga gtgcaatata agcctcggtg gaaatcgcct
     3781 gctcgccgcc ttctttggca ctgcggaagg taaacagcag cggtttttct ggcatggtct
     3841 cacggagaat ttttgctgcc gccatgacag actccacatt ggagaggtcg gcatagtggt
     3901 ccacacgcca ttccagaata tcaaagtccg cttcacgata ggcgagagct tcggatttca
     3961 cgctggcaat atctttcgcc atcagcgaga cgatgatttt aggtgcgccc gtaccaatga
     4021 cgagatcttt tacagttacg gttttcattt tttacccttt ctgcacgcgg tcagcctgtc
     4081 aggcaccgaa ccccatgacc tgtttaacat attccagagg gaaatctttg ccagtccata
     4141 atgtgaactg ttcagcccct tgccacaaca acatgccgta tccatcaatc gttttgcaac
     4201 cagcttgttg cgcctgctgc aataacttcg tcatatgcgg gttatacacg cattcagtga
     4261 ccagaagtcc cggatgtaac agactgatat cattaaccaa tgattcattc tcaaggggtt
     4321 tcatacccac ttttgtgcca ttggttaaaa tgtcggcgga agccagggct tcagcaaagg
     4381 cttgctgatc ggcgagatcg gtgaccgtga cgacacaatc ggtgttttca ttaacccgct
     4441 gcgcgaaggc gagggcttta tcgaagaact catcccgacg gttaaagagt ttaatttctt
     4501 ttaaaccttc aattgccccc tgcgcgccaa ttgccgttga ggcaccaccg gcccctaaca
     4561 gcaccatcgt tttgcctttg atatcaaaac cgctctcttt aatggcgcga atatggcccg
     4621 tgccgtcggt gttatagcca cgcagatagc catcatcatt aacgatggtg ttgatggccc
     4681 ccaccagttt ggcagctggt gttaattcat caacatattc acacgccagt tgtttgttcg
     4741 gcatcgatac accagttccg cgcattttga gggcttttaa tccttcaatt gctccaggaa
     4801 agctatcgtt atccacttcg aaggccatat aggtaaatgg caatcccgct ttttctaagg
     4861 ctttattctg catttcgggc gataaactgt ggcggatagg ataggccatc aacccaatca
     4921 attcgtattt tgcggtaaca tccataatta actcctttaa cctctatgct taattgtgtt
     4981 taaccgggtg caaaatttac gctcgccaaa ccgcacatca ttttcaggaa taatgaaaac
     5041 gcggtaatag cggataaaaa caataattgc ggtaatcagg gccagcagcg cgaaagtaaa
     5101 atcgagaaca atgatatatt gcaggccgat gttcgacaga taaccggtaa tcagtggaat
     5161 aacaaagtta gccagtccac ccatcatcat ataaatactg gtgactttgg ctttgctttt
     5221 gggaaaaaac tctgacatga ccgaaacgcc gagctgtaaa atgccgccag ctgctgagaa
     5281 accgataaca aaggctccgg cattgcacac cagtggagaa gggtacaggt agataatggc
     5341 tgctgttatt gttgccagtg cagagttaaa tacattagcc cagatgggcc ggaccatttt
     5401 tttcagtagt gcggcaaaaa taaagacaca gaccaacgag cccatactgt aataagagat
     5461 ggtttttaat gcctcagctt ctgacatacc agcaaaagcc atcgcatatt tgggcatcca
     5521 caccacaatc acataaaagg tcgagaatgc ggctacaccg aacagtaccg atgaaacacc
     5581 ttccagccag actaacggtt tgctgttcat ttgcggtaat tcattagtta cgctggcgtc
     5641 caccaactgg ctggggaatt tgcttttcaa cagcatcagc gtgatcagta caaatagaat
     5701 acccggaata atcagcccat agccgtacca gatattattg agcaacatat agctcaccag
     5761 cattgggtag aacatttgcc caaatgacac catcgcttta accagtatga ccgccgaacc
     5821 agaggctttc ggaaagcatt ccatgagcgc ggggtagcca cccgtatcca gcgctgagtt
     5881 agcgatacct acgcacactg ccagaccgta ggcgagagtt aaattcgggc aagcgggaat
     5941 accaaagaag aatagcagat acattattac tgccattaat atcaccgccc gacgaccaaa
     6001 cttatcggag atcacaccga agaataaaat actgatcaat cgccccaaac cgataccgga
     6061 aattaagtag gcaatgcccg cgttgtcagt ggaaaacttt tccgccagag atgacatatt
     6121 ttgggcaagc gtaataacac taatgccgtg caggaagtag ctgaagtaaa tacaaagaac
     6181 agccaggata aatggcgtgc tgaaagcctt attttgagac attttcacag ctccttgctg
     6241 aaagataatt tcgttaccgt acgtattgtt ctccgacggt ttacataatt actatactga
     6301 agatgatttt ccctgggtac atggcataaa gtttatgttt ccaggaatat tgcatgtcat
     6361 agtttgtttt tgatcgcgat tttccttagt tagcgcagaa agagttattt atccgtaaga
     6421 tcttgcatga cctgaaaaga atattgcatt acccacccgg agcgacattt tcctttagcg
     6481 agtgatgccg cgtttttttg cggctgcgta agccgataaa cagtgccagt aaaaaaccga
     6541 tggcagcgat ggcggtatcg aaccacataa tatcggcaat acttctttgg gacagatgag
     6601 ccgtaatcaa cggaatagta aaggtcgcaa tactgcccgc actgtaatag atccctgtag
     6661 ctttaccttt agcgtaaggg aaacgttcag ccattaacgt caggccaatt tgcacaacac
     6721 ctccagcaga ggtaaaacca atgacaaaag caaatattat caccacataa aatgtgggat
     6781 gcaggcagac ggtaaacaga gcaataaatg agataaaggt gtacagcatc agtaatgttg
     6841 ttgggcgaac ggtattacga atgagtggag cggtaataaa tacacaaagc agcgaaccca
     6901 cggtgtagat actgagtagt ttgatcgaca tagtgtatga catgcctgca acaaattgtc
     6961 cgtactgtgc cagccactgg ctaaccagat aaaacgttgc cattgagata tagccatata
     7021 aggtataact ggctaaatcg ataattgaac agcgatgttc cgtagagctg gtggttttct
     7081 ttatgacagg taagcgacga cccggatggg gtgggaacgt acaacggtat aaaaacagag
     7141 cgttaataaa cataatgcct gcagcaatca taaaggacca accgaaccac agttcagccc
     7201 acactaacag gctaatgatt agcggtaata aaaattgtcc gctggaaaca aatgctttaa
     7261 ttaaaatatt ggctgtccca ggtgagcgtg gaaaagcttc catcaaactg ggataagtgc
     7321 ctgcatcgag aaaactgttt gccattcccg ccagaaagcc aaaaacataa gcgataatga
     7381 tgttattggt ctgcaggatg ccaaaaaaga aggccatata gcagcacatc ccgagcatga
     7441 taaaagggcg gcgaccaaag cgatcggata ataatcctgc aaaaagcaag acacttaatc
     7501 gaccaatgcc cagcgatgag ataactatcg agacacccgc ggcattagtc tgccaaagtg
     7561 tctccagcga ggccatattc aggctcatca aaaggacgcc cataccatgc accaggtaat
     7621 taaaatacaa cccaagtgcg gtagggaaat agggattttt cataggttct acttagcaaa
     7681 ggtgctttaa aaagtgaagc gatgttgtgt cagcatccgt tcattattgt tgtaacaacg
     7741 acaattcctt tctgtggaaa aattaacaaa gccgctccag atcgtgtgca tataattcag
     7801 cagctaccga ttgatagatc ttccagtcaa taaaattgcc atcagggtag actcgttgaa
     7861 atgcggttaa gtcggggaaa aaacgcatgg tgttgttgcc gatgcggtta tttattttct
     7921 ctatgatggc atgaagatgt ttttttcttt gctgacgcat agccaacagt tgctcgacta
     7981 cacgatcagg aatggcacac ttgccatttt cccactgacg ccagctttca ctgtcaccgg
     8041 tctgggcaat ccaggtcgcg cattcatcaa tagtcatggc aaaaatatgg cggagtgcct
     8101 ggagttcata agcgttcatc gtgtaatggc tgcatgaaat aaacaataaa atataaataa
     8161 cattatcagc ctgctgacgg cttgaagaga gtcacagtat cttgtgcaac attattggaa
     8221 agagtgaggg gcgaggtagc gaagcggaaa aatgttaaaa aaaagcccat cgtgggagat
     8281 gggcaaagac tacacacagc aattcgttgt ttcactcagg ggatttccat gcttataaat
     8341 caatatgttg atttataacc gtgagctaat agtaggcata cggacttttt gcgtcgatca
     8401 gattcgtctc attagtttaa aaactgtaaa gaatttgcga caggtactac cagctgaatg
     8461 gcggtaagca ggaaaatatg gggaagagca agcaaatatc aattagcggt ggttaacaat
     8521 caggcggcag agccgcctga tgagaaatta cttattcggt ttctcgattt cgccaagttc
     8581 ttcgagaatt tcttccggtt ggtccgtcgg cggcgggact tcttccaccc acgcggcaaa
     8641 cagacgccag gaaacggcta acagaaccgg accaataaac agaccgatca tcccgaaagc
     8701 aatcaaacca ccaataacgc cagagagaat caggatcagc ggtaaatcgg cacccatgcg
     8761 aattaacatt gggcggatga cgttatccag cgtgccaacc acaccgctcc acactaacaa
     8821 taccgttccc caggtggtat cgccagtcca gtagagccag ataatcgccg gaatcagtac
     8881 cggcaacggg ccaagctgga caaggcagga gaggatcatt aacaccgtta gcaacgttgc
     8941 ataaggtacg ccggatacgg cgaggccgat accgccaagc actgcctgta ctaacgccgt
     9001 caccaccaca cccagcgcca ccgcgcggat agcctgtgcc gccagcagca cggcggcatc
     9061 tccgcgaacg cctgccagac gggttgcaaa atggcgaatg ccttgtgcca cctgttcacc
     9121 gcgccagtac agcagggcac tgaagagaag catcagcgca caatgcacca taaagcgccc
     9181 gatatgcgcc gcctgcccaa cgaaccaggt ggtggtggtg ccaatataag ggcggacttt
     9241 cgccatgatc gccgtccccc ccatatccag caagttgtgc cagcctgcat acagcttcgc
     9301 gccaatcacc ggaatggtat taagccacgc cagatcgggt aacgtcatgt caccgctgga
     9361 aatggcttta attagcgggc cgctgccgtc gacgatactg ttaaccagca aagcaatagg
     9421 gatgataaac accatcacta ataacagcgt catcaccaga acggcgagag agcggcggcc
     9481 aaacatgatc ttttgcaaac gtaacaatac cggccaggtg gcgataacca ccgtaccggc
     9541 ccatgcaaag ccgagaataa agggttgaac aatccacaga catgccacaa tcatgatggc
     9601 taaaaacagc accgaaagca gaatttgtgc gacatccctg ggctgacgaa catttaccat
     9661 aactactttt cacctttttt gtgcgtcaaa tcgtcgacgc gacgtgaaca cgcgaaactc
     9721 acctgcataa tgatgagcaa tttcagcggt ttttaacagg ccgattctgc ccttaattct
     9781 gatgggcgtg ttagaaaaaa atgtggtaca acaactcagg caacacgcaa acgatttact
     9841 cgtcgtattt caagttgcat gtgctgcggc tacgttcgtt caccccagtc acttactatt
     9901 gtaagctcct ggagttcact cgcttgccgc cttcctgcaa cacgaaatcc atagcgtaaa
     9961 caaacatcac ctttcagtgc gctattgcag cagcctgaaa gaatagtgta tcgacctaca
    10021 tcacagaccg caggaaaggg tcaatataat gattccacag atttcccagg cacccggcgt
    10081 cgttcaactg gtgcttaatt ttttgcaaga gctggagcaa caaggtttta ccggcgatac
    10141 ggcgacaagt tatgccgatc gtctgacaat gtcgaccgac aacagtattt accaacttct
    10201 ccccgatgcg gtggtatttc cgcgttcaac cgcagatgtg gcgctgatcg cccgtcttgc
    10261 cgcgcaggaa cgctattcat cgctgatctt taccccccgc ggcggcggca ccggcactaa
    10321 cggtcaggcg ctcaaccagg ggattattgt tgatatgtcc cgccatatga accgcatcat
    10381 cgaaattaac cctgaagagg gctgggtgcg cgttgaggcc ggggtgataa aagatcaact
    10441 caatcagtac ctgaaaccgt tcggctactt ttttgcgccg gaactttcga ccagcaaccg
    10501 ggcaacgctc ggtgggatga tcaataccga tgcatccggt cagggatcgc tggtctatgg
    10561 caaaacgtca gatcacgtac ttggcgtacg cgcggtgttg ttggggggcg atattctcga
    10621 tacgcaacct ttacccgtcg aattggcgga aacgctgggt aaatccaata ccacaatcgg
    10681 gcgaatttat aacacggttt atcaacgttg ccgtcagcaa cgccagttaa ttatcgacaa
    10741 cttccccaaa cttaaccgct ttcttaccgg ttacgatctg cgtcatgtct ttaacgatga
    10801 gatgaccgag ttcgacctga cgcgcattct gacgggttca gaagggacgc tggcctttat
    10861 taccgaagcg cggctggata ttacacgctt gcctaaagtg cgccgtctgg tgaacgtcaa
    10921 atatgactct tttgactctg cgctgcgtaa cgcgccgttt atggttgagg cgcgggcgct
    10981 ttcggtagag acggtggact caaaagtgct gaatctggcg cgggaagata ttgtctggca
    11041 ttccgtcagc gagttgatta ccgatgtgcc tgaccaagag atgctcgggc tgaacattgt
    11101 ggaatttgct ggtgatgatg aggcgctgat tgatgagcgg gtaaatgcac tctgtgcgcg
    11161 gttggatgag ctgatcgcca gtcatcaagc aggtgtcatc ggctggcagg tgtgccgtga
    11221 gctggcgggg gttgaacgta tctatgcaat gcgcaaaaaa gccgttggtc tgcttggcaa
    11281 tgccaaaggt gccgctaagc caattccgtt tgctgaggat acctgcgtac cgccggaaca
    11341 cctggcggat tatattgctg aatttcgcgc gctgctcgac agccacggct taagctacgg
    11401 tatgttcggt cacgtcgacg caggtgtctt gcacgtccgt ccagcgctgg atatgtgcga
    11461 tcctcaacaa gagattttga tgaagcaaat ctctgatgac gtggtggcgc tgactgcgaa
    11521 atacggtggt ttgttgtggg gcgagcacgg caaaggtttt cgcgctgaat acagcccggc
    11581 gtttttcggt gaggaacttt ttgcagaact gcgcaaagtg aaagcggcat ttgacccgca
    11641 taaccgactc aacccaggga agatttgccc gccagaaggt ctcgatgcgc cgatgatgaa
    11701 agtggacgcg gtgaagcgcg gtacattcga tcggcagatc cccattgcgg tacgccagca
    11761 gtggcgcggt gcgatggagt gtaacggcaa cggtttatgc ttcaactttg atgcccgtag
    11821 tccgatgtgt ccgtcgatga agatcaccca gaaccggatt cattcaccga aagggcgcgc
    11881 aacgctggtg cgtgaatggc tgcgtttgtt ggcggatcgc ggcgttgatc cactcaaact
    11941 ggaacaagaa ctgcctgaat ccggcgtcag tttgcggacg ttaattgccc gcacgcgcaa
    12001 tagctggcat gcgaataaag gcgaatatga cttctcacac gaagtcaaag aggcgatgtc
    12061 gggctgtctg gcctgtaaag cgtgttcgac ccagtgcccc atcaaaattg atgtgccgga
    12121 gtttcgctct cgttttctgc agctctatca cacccgttat ttacgcccgc tgcgcgacca
    12181 cctcgtcgct acggtcgaga gctacgcgcc gctgatggca cgcgcgccga aaacctttaa
    12241 cttcttcatt aaccagccgc tggtgcgcaa actctcggaa aaacatatcg gcatggttga
    12301 tttgccgctg ctgtcggtcc cctcgctaca acaacaaatg gtggggcatc gctcggcaaa
    12361 catgacgctg gaacagcttg aatctctcaa tgcagagcag aaagcgcgca cagtgttggt
    12421 ggtgcaggac ccctttacca gctattacga tgcgcaagtg gtggcggatt ttgtccgtct
    12481 ggtcgaaaaa ttaggtttcc agcctgtgtt actgccattt tcgccaaatg gcaaagccca
    12541 gcatattaaa ggttttctta atcgttttgc gaagacggcg aaaaagacgg cggatttcct
    12601 caaccgtatg gcgaagctgg gtatgccaat ggtgggcgtc gatccggcgc tggtactttg
    12661 ttatcgcgat gaatataaac tggcgctggg cgaggagcgt ggcgagttta acgtcttact
    12721 ggcgaatgaa tggctggcaa gcgcacttga gtcacagcca gtggctacag tcagcggtga
    12781 atcatggtat ttctttggtc actgtaccga agttaccgcc ttgccgggtg cgccagcaca
    12841 atgggccgcg atatttgccc gttttggcgc gaaactggaa aatgtcagcg tgggttgctg
    12901 cggcatggca gggacttacg gacatgaagc gaaaaaccat gaaaattcgc tcgggatcta
    12961 tgagttatcc tggcatcagg ctatgcagcg actgccgcgt aaccgctgtc tggcgaccgg
    13021 atattcctgc cgtagccagg taaaacgggt tgaaggcacg ggggtacgcc atcctgtgca
    13081 ggctttactg gagattatta aatgatatgg aaacggaaaa tcaccctgga agcactgaat
    13141 gctatgggtg aaggaaacat ggtggggttc ctggatattc gctttgaaca tattggtgat
    13201 gacacccttg aagcgacaat gccagtagac tcgcggacaa agcagccttt cgggttgctg
    13261 catggaggag catccgtggt actggccgaa agtatcggtt ccgttgccgg ttatttatgt
    13321 accgaaggtg agcaaaaagt ggttggtctg gaaatcaatg ctaaccacgt ccgctcggca
    13381 cgagaagggc gggtgcgcgg cgtatgcaaa ccgttgcatc tcggttcgcg tcaccaggtc
    13441 tggcagattg aaatcttcga tgagaaaggg cgtttgtgct gttcgtcacg attgacgacc
    13501 gccattttgt gacgttgtca ccagaaaagt gtgacgcata ttgcttttgg tcattatctg
    13561 cacagtaaac ggtggtatac tgtgcaggtc ttgtctaaaa gcgaggatgc tatgtctact
    13621 caacttgatc ccacccagct ggccattgaa tttttacgcc gtgaccagag caatctttca
    13681 cctgcccaat atctcaaacg tctgaaacaa ctagaacttg aatttgctga cctgcttact
    13741 ctctcttctg ctgaattaaa agaagaaatc tactttgcct ggcgtctggg cgtgcattga
    13801 tcctgactta atgccgcaag ttcgccaaat cgacctggat taacctccgt ccaggttcga
    13861 tgaccttctt aatactgctt atctaccgcc tgatattgtt caaaaataat actaatcgca
    13921 gtttgtgtta aaacggcggg ttagctttat gagattattc ttatcgcccc ttcaagagct
    13981 aagccactga gagtgccgga gataagcgcc ggatggggta gaaaccctta agcctgtgtc
    14041 gcacagactt aagggttttc ttatttctga acgctgcact tttttaccta tctcttaaat
    14101 agtcattttc aatacaactt tttctttttc atcacagcct taatgctcct tagataataa
    14161 ccattatcta acaatgagat acctaattct tagcgtgcct gttaacccac acatcagggt
    14221 ctatgcttat taaaagcagg caaaaagcat gttttacggt aaagcccctg cgtttgctgg
    14281 gttgaactga taatcattat cactaacatg ctgttatacg ctgaaagcga tgaagtgagg
    14341 taaatcgatg gacatgcatt caggaacctt taacccacaa gatttcgcct ggcaaggctt
    14401 aacgctgaca cccgcagcgg cgatacacat ccgtgagctg gtggcaaagc agccgggtat
    14461 ggtcggcgtg cgcttaggcg tgaagcaaac gggctgcgcg ggctttggct atgtgctcga
    14521 cagtgttagc gagccggaca aagacgatct gctgtttgaa cacgacggcg cgaagctgtt
    14581 tgtcccgctg caagcgatgc cgtttattga tggcacggaa gtcgatttcg ttcgtgaagg
    14641 acttaatcag atattcaaat ttcacaaccc taaagcccag aatgaatgtg gctgtggcga
    14701 aagctttggg gtataggcgg tactatgtct cgtaatactg aagcaactga cgatgtcaaa
    14761 acctggaccg gcggcccgct gaattataaa gaaggattct tcacccagtt agccaccgat
    14821 gagctggcaa aggggataaa cgaagaggtg gtgcgcgcaa tttcggcgaa gcgtaatgag
    14881 ccggagtgga tgctggagtt tcgtctaaac gcctatcgcg catggctgga gatggaagaa
    14941 ccgcactggt tgaaagcgca ctacgacaag ctgaattatc aggattacag ctactactca
    15001 gcaccatcgt gcggtaattg tgacgacact tgcgcgtctg aacctggcgc ggtgcagcaa
    15061 actggcgcga acgccttttt aagtaaagag gtggaggcgg cgtttgagca gttgggcgtt
    15121 cccgtgcggg aaggcaaaga ggtggcggtg gatgccattt tcgactcagt ttcggttgcc
    15181 actacttatc gcgaaaaact ggcggagcag ggaattattt tctgttcctt tggtgaggcg
    15241 atccacgatc acccggaact ggtgcgtaaa tatctcggca ccgtggtgcc ggggaatgac
    15301 aacttctttg ccgcgcttaa tgcggcggta gcctctgacg gtacgtttat ttatgtgcct
    15361 aaaggcgtgc gctgcccgat ggaactttcc acctattttc gcattaacgc agaaaaaacc
    15421 gggcagtttg agcgcaccat tctggtggcc gacgaagaca gctacgtcag ctacattgaa
    15481 ggctgttccg ctccggtgcg tgacagctat cagttacacg cggcagtggt ggaagtcatc
    15541 atccataaaa acgccgaggt gaaatattcc acggtacaaa actggtttcc tggcgataac
    15601 aacaccggcg gtattctcaa cttcgtcacc aagcgtgctt tgtgcgaagg cgaaaacagc
    15661 aaaatgtcat ggacgcaatc agaaaccggg tcagcgatta cgtggaaata tcccagctgc
    15721 attttgcgcg gcgataactc cattggtgag ttttactcag tggcgctgac cagcggtcat
    15781 cagcaagcgg ataccggcac caagatgatc cacatcggta aaaacaccaa atcgaccatt
    15841 atctcgaaag ggatctctgc cggacatagt cagaacagtt atcgcggctt agtgaaaatc
    15901 atgccgacgg caaccaatgc gcgcaatttc actcagtgcg actcaatgct gattggcgct
    15961 aattgtgggg cgcatacctt cccgtatgtt gagtgtcgta acaatagtgc gcaactggaa
    16021 cacgaggcaa cgacatcacg tattggtgaa gatcaactgt tttactgcct gcaacgcggg
    16081 atcagcgaag aagacgccat ctcgatgatt gttaacggtt tctgcaaaga cgtgttctcg
    16141 gagctgccgt tggaatttgc cgttgaagca caaaaactcc tcgccatcag tcttgaacac
    16201 agcgtcggat aaggaataaa catgttaagt attaaagatt tacacgtcag cgtggaagat
    16261 aaagctatcc tgcgcggatt aagcctcgac gttcatcccg gcgaagttca cgccattatg
    16321 gggccaaacg gttcgggcaa aagtacctta tcggcaacgc ttgccgggcg agaagattat
    16381 gaagtgacgg gcggcacggt tgagttcaaa ggcaaagatt tgcttgcgct gtcgccggaa
    16441 gatcgcgcgg gcgaaggcat ctttatggcc ttccagtatc cggtggagat tccaggtgtc
    16501 agtaaccagt ttttcctgca aacggcactt aatgcggtgc gcagctatcg cggccaggaa
    16561 acgctcgacc gctttgattt tcaggatttg atggaagaga aaatcgctct cctgaagatg
    16621 ccggaagatt tattaacccg ttcggtaaac gttggttttt ccggcggcga gaaaaagcgc
    16681 aacgatattt tgcaaatggc ggtgctggaa ccggagttat gcattcttga tgagtcggac
    16741 tccgggctgg atattgacgc attaaaagtg gtcgccgatg gcgtgaactc gctgcgtgat
    16801 ggcaagcgct cattcatcat tgttacgcac taccaacgca ttctcgacta catcaagcct
    16861 gattacgttc atgtgctata tcagggacga attgtgaaat ccggcgattt cacgttggtc
    16921 aaacaactgg aggagcaggg ttatggctgg cttaccgaac agcagtaacg cgctgcaaca
    16981 gtggcatcac ttgtttgaag ctgaagggac aaaacgctcc ccgcaagcac agcagcattt
    17041 acaacaattg ctgcgtaccg gactgccgac acgtaaacat gaaaactgga aatatacgcc
    17101 gctggaaggg ctgatcaata gccagtttgt cagcattgcg ggagagatat ccccacagca
    17161 gcgtgatgcc ttagcgttaa cgttagactc cgtgcggctg gtgtttgtcg atgggcgtta
    17221 cgtgcccgca ctgagcgatg caactgaagg cagcggatat gaagtgagca ttaacgacga
    17281 ccgtcagggt ttacccgacg ctattcaggc ggaagtgttt ctgcatttga cggaaagcct
    17341 ggcacaaagc gtgacgcata tcgccgtgaa gcgcggtcaa cggccggcaa agccattgct
    17401 gttaatgcat atcacccagg gcgtggcagg tgaagaggtg aacactgccc attaccgaca
    17461 tcatctggat ctggcggaag gtgccgaagc aacggtgatc gaacattttg tcagcctgaa
    17521 tgatgctcgt cattttaccg gggcacggtt cactatcaac gtcgcagcga atgcccactt
    17581 gcagcatatc aagctggcgt ttgaaaaccc gctcagtcac cactttgctc ataacgattt
    17641 gttgctggct gaggatgcca ccgcatttag ccacagtttc ctgctgggtg gcgcagtgtt
    17701 acgacacaac accagtacgc aactcaatgg cgaaaacagc acgctgcgga tcaatagcct
    17761 ggcgatgccg gtgaaaaacg aggtgtgtga tacccgtacc tggctggaac acaataaagg
    17821 tttttgtaac agccgacagt tgcacaaaac tatcgtcagc gacaaaggcc gcgcggtatt
    17881 taacggtttg atcaacgtcg cgcagcacgc catcaaaacg gatggtcaga tgaccaacaa
    17941 caatctgctg atgggcaaac tggcggaagt ggatacgaaa ccgcagctgg aaatctatgc
    18001 agatgatgtg aaatgcagcc acggcgcgac ggtggggcgt attgatgatg aacagatatt
    18061 ctatctgcgc tcgcgcggga tcaatcagca ggatgcccag cagatgatca tttacgcctt
    18121 cgctgccgaa ctgacggaag cactgcgtga tgaggggctt aaacagcagg tgctggcccg
    18181 aatcggtcaa cggctgccag gaggtgcaag atgatttttt ccgtcgacaa agtgcgggcc
    18241 gactttccgg tgctttcgcg tgaggtaaac ggtttgccgc tggcttatct cgacagcgcc
    18301 gccagtgcgc agaaaccgag ccaggtgatt gacgccgagg ccgagtttta tcgtcatggc
    18361 tacgcggcgg tgcatcgtgg tattcatacc ttaagcgccc aggcgaccga gaaaatggag
    18421 aacgtgcgca agcgggcatc gctgtttatt aatgcccgtt cggcggaaga gctggtgttc
    18481 gtccgcggca cgacggaagg gatcaatctg gtcgccaata gctggggcaa cagcaacgtg
    18541 cgggcgggcg ataacatcat catcagtcag atggagcacc acgctaacat tgttccctgg
    18601 cagatgcttt gcgcacgcgt tggcgcagag ctgcgtgtga tcccgctcaa tcccgatggt
    18661 acgttgcaac tggagacgct gcctacgctg tttgatgaga aaactcgcct gctggcaatt
    18721 actcatgtct ccaacgtgct tggcacagaa aatccactgg cggaaatgat cacgcttgcg
    18781 caccagcatg gcgcaaaagt gctggtggat ggcgctcagg cggtgatgca tcatccggtg
    18841 gatgttcagg cgctggattg cgacttttac gtgttctccg ggcataaact gtatggcccc
    18901 accggaattg gcattcttta tgtgaaagaa gccttgttgc aggagatgcc gccgtgggaa
    18961 gggggcggtt ctatgatcgc caccgtcagc ctgagtgaag gcactacctg gaccaaagca
    19021 ccatggcggt ttgaagccgg tacacccaat accgggggca tcattggtct tggcgcggcg
    19081 ctggagtatg tttcggcgct ggggcttaat aacatagccg agtatgaaca gaatctgatg
    19141 cattatgcgc tatcacagct ggaatctgta ccggatctca ctctctatgg cccacaaaac
    19201 aggcttggcg ttattgcttt taatctcggt aaacaccacg cctatgatgt tggcagtttt
    19261 ctcgataatt acggcattgc tgtgcgtacc ggacatcact gcgcaatgcc attgatggcc
    19321 tattacaacg tccctgcgat gtgtcgggcg tcgctggcca tgtataacac ccatgaagaa
    19381 gtggatcgtc tggtgaccgg cctgcaacgt attcaccgtt tgctgggata acagggaggc
    19441 actatggctt tattgccgga taaagaaaag ttgctgcgta attttttacg ctgcgccaac
    19501 tgggaagaga aatatctcta cattattgag ctgggccagc gtctgccaga attacgcgac
    19561 gaagacagaa gtccacaaaa tagcattcag ggctgtcaga gtcaggtgtg gattgtcatg
    19621 cgccagaatg cccagggaat tattgaatta cagggcgaca gcgatgcggc gattgtgaaa
    19681 gggcttattg cggtcgtctt tattctctac gatcagatga cgccgcagga tattgtcaat
    19741 ttcgatgtgc gtccgtggtt tgaaaaaatg gcgctcaccc aacatctcac cccatctcgt
    19801 tcacaaggtc tggaagcgat gattcgcgca attcgcgcca aagccgctgc acttagctaa
    19861 actaaaagga cagctttcat ccggttggct cacattgccg gatggtcaat gtttacactg
    19921 acctgcacag gagtgttttg gtttcaggtg aacataagcg ccatccgacg tttcagcgtg
    19981 agtctccggc aaatacagga ggtttacaat gaaacgcgcg tctttgctta cactcacgct
    20041 tatcggcgct tttagcgcca tccaggctgc ctgggcggtt gattatccgc taccaccaac
    20101 cggaagccga ctggttgggc aaaatcaaac gtatacggtg caagaagggg ataaaaacct
    20161 tcaggctatt gcccgacgtt ttgatactgc ggcaatgttg atccttgaag ccaataacac
    20221 tatcgccccg gtgccaaaac ctggtacgac gataactatt ccttcacaac tgttattacc
    20281 tgatgcaccg cgtcagggga ttatcgttaa ccttgcagag ctgcgccttt attattatcc
    20341 gccgggagaa aatattgtgc aggtttatcc aataggtatt ggattgcagg ggctggaaac
    20401 gccggtgatg gaaacgcgtg ttgggcagaa aatccctaac ccaacctgga cgcctacggc
    20461 aggcattcgt cagcgttcgc tggagcgtgg cattaaatta ccgccagtcg ttcctgccgg
    20521 accaaataac ccgctaggac gttacgcact gcgcctcgcg catggtaatg gcgaatacct
    20581 cattcatggt accagtgcgc cggacagcgt cggtttgcgc gtcagttcag ggtgtattcg
    20641 catgaatgca ccggatatta aagccttgtt ctccagcgtg cggacgggaa cgccggtgaa
    20701 agtgatcaac gaaccggtga aatattccgt ggagcctaac gggatgcgtt atgttgaagt
    20761 acatcgacca ctatcggcag aagaacagca gaacgttcag acaatgccat acacactgcc
    20821 agcaggcttt acgcaattta aagacaataa ggctgtagat cagaagttag tcgataaagc
    20881 gttgtatcgt cgggcagggt atccggtttc ggtgagcagt ggagcaactc ccgcagccag
    20941 caatgcgcct tcagtagagt cagcgcagaa tggtgaacca gagcaaggga atatgttacg
    21001 cgtgacgcag tagcggtaaa cggcagacaa aaaaaatggc gcacaatgtg cgccattttt
    21061 cacttcacag gtactattac ttgcggtatt tagtagccat gttgtccaga cgctggttag
    21121 cacgagctgc gtcatcttta gcagcctgaa cgtcggaacg cattgcgttc acgtcgttgc
    21181 tcagctggtc aactttagcg ttcagagtct gaacgtcaga agacagctga tcgattttag
    21241 cgttgctgga gcaacctgcc agcagagtag aacccaggat taccgcgccc agtaccagtt
    21301 tagtagcttt cattattaat accctctaga ttgagttaat ctccatgtag cgttacaagt
    21361 attacacaaa gttttttatg ttgagaatat ttttttgatg ggaaggcact tatttttgat
    21421 cgttcgctca aagaagcatc gaacgctggg ttttagataa aaaaattgag agaaaacagg
    21481 atgcttccat cggattcatc ttagataaag tgagattata tagtgaaatc cgatttgatt
    21541 ttttattgct tctggttatc gattaaataa aaaaagcgcc catcagggcg cttcgatata
    21601 caaattaatt cacaaaagca atattacagg acgtgaacag atgcggtgtt agtagtgccg
    21661 ctcggtacca gtgcaccaga aaccataact acaacgtcac ctttgtgtgc cagaccgctc
    21721 tgcagagcca gttctttacc cagacggtag aaatcatcag tagaagtgat ctctttaaca
    21781 agctgcggca caacgccttt gctcagtacc aactgatgag ccgttttttc gttggtggtc
    21841 agtgccagga tggtggcatc cgggaagtat ttacgtactg cgcgagcaga tttaccgccc
    21901 tgagtagcaa ccacgatcag cggagcatcc agtttttcag cagtttcaac ggcaccacgg
    21961 cataccgctt cggtaatgcg cagtttacgg ttgtcattgt tgaactcgag acggctgttc
    22021 atcacgcggt cggtacgttc gcagatggtc gccatgatag aaaccgcttc cagcgggtat
    22081 ttaccttttg cggattcacc agacagcatc actgcgtcag taccgtcgag gatggcgttt
    22141 gcaacgtcac cggcttctgc gcgagtcggg cgtgggtttt tgatcatgga atccagcatc
    22201 tgggtcgcag tgataacgac tttacgtgca cggatacatt tttcgatcat catcttctgg
    22261 gcgaagataa cttcttctac cgggatttct acacccaggt cgccacgcgc aaccatgatg
    22321 ccgtcagagg cttcgaggat ttcgtcgaag ttgttgaggc cttcctggtt ttcgattttg
    22381 gagatgatgt ggatgttttc gccgccgtgc gctttcaggt gctcacggat ttcgataacg
    22441 tcagaacgct tacgaataaa ggaagcagca acaaagtcta cgccttgttc gcaaccaaag
    22501 atcaggtcct gtttgtcttt ttcagccagt gctggcagag caatggaaac gccaggcagg
    22561 ttcacacctt tgttttcgcc caggtcaccg ttgttcagca ctttacagat aactttgtta
    22621 ccttcaatgg cggtaacttc cataccgatc agaccatcgt caaccagtac ggtgttgcca
    22681 acagacaggt cagtagtgaa accttcatac gttaccgcaa ccatttcgct gttgccgata
    22741 acagatttat cagtggtgaa agtaaaggtc tgaccagctt tcagagaaac gtcgttaccg
    22801 ccttccagtt tcatggtgcg gatttccgga cctttggtat caagcaggat agcggcggtt
    22861 ttaccagttt tgctcatcac gttgcgcaga ttctgaatgc gctgaccgtg ttctgcatag
    22921 tcaccatgag agaagttcag acgcataacg ttcatgccag cgtccagcat tttagctaac
    22981 atctcttcag attcggtttt cggtccgatg gtgcaaacaa ttttggtctt tttcatgaca
    23041 gtcttagtct ttaagttgag aaggatggga gaaacttgct ttctgggcgc actgccggaa
    23101 agcgaatccg gtattacgaa agtggtggtg cctcgctcta aggataggtg acatcgaaaa
    23161 agcgtgcaga ggaatgtgtg cttgtgtctc agcccaacgt gagtgcctgt ttttgagtcg
    23221 ttgagttcta cagtccaaag tgctgaaacc attcaagagt caattggcgc gcattatacg
    23281 ctgaaattaa tccaaaagga aaacaaaaac agcgtttcaa aaaatataca acttgttaga
    23341 caataaattg ttatcaaaga tttaacgttc cagggaaaag gttacgcaaa aacttcactg
    23401 tttgcgcaac gtctggtgcc gaagttgtca gtgtgaggat aagtgaaagt tcatccggtg
    23461 tataaatata tcatcgctca attgctacag ttaaaataat ttatcgcgtt atttgtctga
    23521 ttttgtttga tttttgttta attggttaga ttgatatatg ctgatagttg gcatgataaa
    23581 taggtataaa gaatgggaaa tcggacaaaa gaggatgaac tgtaccgaga aatgtgcaga
    23641 gttgtcggta aagttgtgct ggaaatgcgc gatctggggc aggaaccaaa gcatattgtt
    23701 atcgcaggcg tattacgtac agcattagcc aataaacgca ttcagcgcag tgagctggaa
    23761 aagcaggcga tggaaaccgt cattaacgca ctggtaaaat gaccattcag gatgaggcgg
    23821 taagcttcat cctgatattc ttgcttcagt tgcggtccag ttaatcattc taaataacaa
    23881 ctgctgaaat tatacgaatt tcggtatgta ttttaattta tagcgataat gttattttta
    23941 t
//
LOCUS       DACAOP010000071        23570 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.071, whole genome shotgun sequence.
ACCESSION   DACAOP010000071 DACAOP010000000
VERSION     DACAOP010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23570
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.071"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(96..353)
                     /locus_tag="IT892_003053"
     CDS             complement(96..353)
                     /locus_tag="IT892_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136243.1"
                     /translation="MQKPLPVRWLIIQGLTENEHCGIQAYACNTESQEDLYAEVPLVG
                     RLTGIEEVKVEAIAMSKLHNMSFPPYMGHSAAVIFHLIYLS"
     gene            476..2444
                     /locus_tag="IT892_003054"
                     /pseudo
     CDS             476..2444
                     /locus_tag="IT892_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415220.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
     gene            2441..3760
                     /gene="potE"
                     /locus_tag="IT892_003055"
     CDS             2441..3760
                     /gene="potE"
                     /locus_tag="IT892_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine-ornithine antiporter"
                     /protein_id="HAP3136244.1"
                     /translation="MSQAKSNKMGVVQLTILTMVNMMGSGIIMLPTKLAEVGTISIIS
                     WLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVA
                     IAISAVGYGTELLGASLSPVQIGLATIGVLWICTVANFGGARITGQISSITVWGVIIP
                     VVGLCIIGWFWFSPTLYVDSWNPHHAPFFSAVGSSIAMTLWAFLGLESACANTDVVEN
                     PERNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMELANSTAPFGLAFAQMFTPEVGKV
                     IMALMVMSCCGSLLGWQFTIAQVFKSSSDEGYFPKIFSRVTKVDAPVQGMLTIVIIQS
                     GLALMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKVANVPPSKAKVANFVA
                     FVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG"
     gene            3788..3985
                     /locus_tag="IT892_003056"
                     /pseudo
     CDS             3788..3985
                     /locus_tag="IT892_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405579.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4109..4759
                     /locus_tag="IT892_003057"
     CDS             4109..4759
                     /locus_tag="IT892_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2625 domain-containing protein"
                     /protein_id="HAP3136245.1"
                     /translation="MREMNQLVNTEDSAWPIIQNWLKDATNHTELLPVNKDLAETALY
                     QLQVTTKSPMGALVYGSGGLLIDNGWLRIAGSGHPRLPRDPVSWTQRPEFAGVRALPI
                     ADDVAGGIFALNGGDLGEDTGCVYYFAPDTLNWESLEVGYSEFLQWALSGDLDTFYEN
                     VRWQQWREDVIKLSATEAFTFYPFLWVQSEEARTRKVISLTELWEMQYQMKETFTQ"
     gene            complement(4800..5294)
                     /locus_tag="IT892_003058"
     CDS             complement(4800..5294)
                     /locus_tag="IT892_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136246.1"
                     /translation="MKTNRSLVVIVSLITATLLLTACAQPEQSSLAGDWLLTPKDKTR
                     GLTGSIAVNIAPFRCKTNCRGDNLPDNTRRWQLSGGNEKELTYLHNMSAQEKVGLNPG
                     WQCYTSFFMRVCQGKPGTRPIVNEDYVSESGFFGSMMHVGIIELRRCQSENCQQELKA
                     INTH"
     gene            complement(5508..7148)
                     /gene="pgm"
                     /locus_tag="IT892_003059"
     CDS             complement(5508..7148)
                     /gene="pgm"
                     /locus_tag="IT892_003059"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-glucose phosphate-specific
                     phosphoglucomutase"
                     /protein_id="HAP3136247.1"
                     /translation="MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGT
                     SGHRGSAARHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVL
                     AANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
                     NGGPADTNVTKVVEDRANALLADGLKGVKRISLDEAMASGHVKEQDLVQPFVEGLADI
                     VDMAAIQKAGLTLGVDPLGGSGIEYWKRIGEYYNLNLTIVNDQVDQTFRFMHLDKDGA
                     IRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQ
                     HRPQWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEES
                     AGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAKRFGAPSYNRLQA
                     AATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARP
                     SGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA"
     gene            complement(7174..7719)
                     /gene="seqA"
                     /locus_tag="IT892_003060"
     CDS             complement(7174..7719)
                     /gene="seqA"
                     /locus_tag="IT892_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation negative regulator SeqA"
                     /protein_id="HAP3136248.1"
                     /translation="MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFSAASQPAAP
                     VTKEVRVASPAIVEAKPVKTIKDKVRAMRELLLSDEYAEQKRAVNRFMLLLSTLYSLD
                     AQAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMI
                     EHIMQSMQFPAELIEKVCGTI"
     gene            7904..8668
                     /gene="ybfF"
                     /locus_tag="IT892_003061"
     CDS             7904..8668
                     /gene="ybfF"
                     /locus_tag="IT892_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAP3136249.1"
                     /translation="MKLNIRAQTAQNQHNNSPIVLVHGLFGSLDNLGVLARDLVNDHN
                     IIQVDMRNHGLSPRDPVMNYPAMAQDLVDTLDAQQIDKATFIGHSMGGKAVMALTALA
                     SDRIDKLVAIDIAPVDYHVRRHDEIFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQ
                     FLLKSFVDGEWRFNVPVLWDQYPHIVGWEKIPAWDHPALFIPGGNSPYVSEQYRDDLL
                     AQFPQARAHVIAGAGHWVHAEKPDAVLRAIRRYLND"
     gene            8739..9101
                     /gene="ybfE"
                     /locus_tag="IT892_003062"
     CDS             8739..9101
                     /gene="ybfE"
                     /locus_tag="IT892_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA regulated protein"
                     /protein_id="HAP3136250.1"
                     /translation="MYYGALSIRAEAWLIVSPEVTKIMAKEQTDRTTLDLFAHERRPG
                     RPKTNPLSRDEQLRINKRNQLKRDKVRGLKRVELKLNAEAVEALNELAESRNMSRSEL
                     IEEMLMQQLAALRSQGIV"
     gene            9241..9771
                     /gene="fldA"
                     /locus_tag="IT892_003063"
     CDS             9241..9771
                     /gene="fldA"
                     /locus_tag="IT892_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HAP3136251.1"
                     /translation="MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDL
                     EAYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDAL
                     GTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW
                     VKQISEELHLDEILNA"
     gene            9981..10067
                     /gene="uof"
                     /locus_tag="IT892_003064"
     CDS             9981..10067
                     /gene="uof"
                     /locus_tag="IT892_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fur leader peptide"
                     /protein_id="HAP3136252.1"
                     /translation="MIRIISRANSVTSSNEVNRLVTGQIPHD"
     gene            10060..10506
                     /gene="fur"
                     /locus_tag="IT892_003065"
     CDS             10060..10506
                     /gene="fur"
                     /locus_tag="IT892_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HAP3136253.1"
                     /translation="MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLI
                     DMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEF
                     SDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK"
     gene            complement(10590..10916)
                     /locus_tag="IT892_003066"
     CDS             complement(10590..10916)
                     /locus_tag="IT892_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136254.1"
                     /translation="MKKLILIAIMASGLVACAQSTAPQEDSRLKEAYSACINTAQGSP
                     EKIEACQSVLNVLKKEKQHQQFADQESVRVLDYQQCLRATQTGNDQAVKADCDKVWQE
                     IRSNNK"
     gene            complement(10966..12372)
                     /gene="chiP"
                     /locus_tag="IT892_003067"
     CDS             complement(10966..12372)
                     /gene="chiP"
                     /locus_tag="IT892_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitoporin"
                     /protein_id="HAP3136255.1"
                     /translation="MRTFSGKRSTLALAIAGVTAMSGFMAMPEARAEGFIDDSTLTGG
                     IYYWQRERDRKDVTDGDKYKTNLSHSTWNANLDFQSGYAADMFGLDIAAFTAIEMAEN
                     GDSSHPNEIAFSKSNKAYDEDWSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLL
                     APHWSFMPGTYQGAEAGANFDYGDAGALSFSYMWTNEYKAPWHLEMDEFYQNDKTTKV
                     DYLHSFGAKYDFKNNFVLEAAFGQAEGYIDQYFAKASYKFDIAGSPLTTSYQFYGTRD
                     KVDDRSVNDLYDGTAWLQALTFGYRAADVVDLRLEGTWVKADGQQGYFLQRMTPTYAS
                     SNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGFAIGASYVYAWDAKPATWQS
                     NPDAYYDKNRTIEESAYSLDAVYTIQDGRAKGTMFKLHFTEYDNHSDIPSWGGGYGNI
                     FQDERDVKFMVIAPFTIF"
     gene            complement(12949..14613)
                     /gene="glnS"
                     /locus_tag="IT892_003068"
     CDS             complement(12949..14613)
                     /gene="glnS"
                     /locus_tag="IT892_003068"
                     /EC_number="6.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase"
                     /protein_id="HAP3136256.1"
                     /translation="MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGH
                     AKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSD
                     YFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEK
                     MRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCI
                     SDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNL
                     LVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIRE
                     DLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRAD
                     FREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADG
                     RKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSL
                     KDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE"
     gene            complement(14816..16762)
                     /gene="nagE"
                     /locus_tag="IT892_003069"
     CDS             complement(14816..16762)
                     /gene="nagE"
                     /locus_tag="IT892_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetyl glucosamine transporter subunit
                     IIABC"
                     /protein_id="HAP3136257.1"
                     /translation="MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVAFIAQA
                     GGAIFDNLALIFAIGVASSWSKDSAGAAALAGAVGYFVLTKAMVTINPEINMGVLAGI
                     ITGLVGGAAYNRWSDIKLPDFLSFFGGKRFVPIATGFFCLVLAAIFGYVWPPVQHAIH
                     AGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGTVFHGDINR
                     FYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAVTAFLTGV
                     TEPLEFLFMFLAPLLYLLHALLTGISLFVATLLGIHAGFSFSAGAIDYALMYNLPAAS
                     QNVWMLLVMGVIFFAIYFVVFSLVIRMFNLKTPGREDKEDEIVTEEANSNTEEGLTQL
                     ATNYIAAVGGTDNLKAIDACITRLRLTVADSARVNDTMCKRLGASGVVKLNKQTIQVI
                     VGAKAESIGDAMKKVVARGPVAAASAEATPATAAPVAKPQAVPNAVSIAELVSPITGD
                     VVALDQVPDEAFASKAVGDGVAVKPTDKIVVSPAAGTIVKIFNTNHAFCLETEKGAEI
                     VVHMGIDTVALEGKGFKRLVEEGAQVSAGQPILEMDLDYLNANARSMISPVVCSNIDD
                     FSGLIIKAQGHVVAGQTPLYEIKK"
     gene            17095..17895
                     /gene="nagB"
                     /locus_tag="IT892_003070"
     CDS             17095..17895
                     /gene="nagB"
                     /locus_tag="IT892_003070"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008805656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAP3136258.1"
                     /translation="MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGT
                     PMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAE
                     NINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIK
                     TLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEG
                     CVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL"
     gene            17955..19103
                     /gene="nagA"
                     /locus_tag="IT892_003071"
     CDS             17955..19103
                     /gene="nagA"
                     /locus_tag="IT892_003071"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAP3136259.1"
                     /translation="MYALTQGRIFTDHEFLDDHAVVIADGLIKSVCPVAELPPEIEQR
                     SLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNYLPTLITT
                     SDELMKQGVRVMREYLAKHPNQALGLHLEGPWLNLVKKGTHNPNFVRKPDAALVDFLC
                     ENADVITKVTLAPEMVPAEVISKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLY
                     NAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRNAKRLKGDKLCLVTDATA
                     PAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRM
                     ATLYPARAIGVEKRLGTLAAGKVANLTAFTPDFKITKTIVNGNEVVTQ"
     gene            19112..20332
                     /gene="nagC"
                     /locus_tag="IT892_003072"
                     /gene_synonym="nagR"
     CDS             19112..20332
                     /gene="nagC"
                     /locus_tag="IT892_003072"
                     /gene_synonym="nagR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NagC"
                     /protein_id="HAP3136260.1"
                     /translation="MTPGGQAQIGNVDLVKQLNSAAVYRLIDQYGPISRIQIAEQSQL
                     APASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDATITL
                     FDLSSKVLAEEHYPLPERTQQTLEHALLNAIAQFIDSYQRKLRELIAISVILPGLVDP
                     DSGKIHYMPHIQVENWGLVEALEERFKVTCFVGHDIRSLALAEHYFGASQDCEDSILV
                     RVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQ
                     RVLNLLKQGYQSRVPLDDCTIKTICKAANKGDSLASEVIEYVGRHLGKTIAIAINLFN
                     PQKIVIAGEITKADKVLLPAIESCINTQALKAFRTNLPVVRSELDHRSAIGAFALVKR
                     AMLNGILLQHLLEN"
     gene            20380..21132
                     /gene="nagD"
                     /locus_tag="IT892_003073"
     CDS             20380..21132
                     /gene="nagD"
                     /locus_tag="IT892_003073"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide monophosphatase NagD"
                     /protein_id="HAP3136261.1"
                     /translation="MTIKNVICDIDGVLMHDNVAVPGAAEFLHGIMDKGLPLVLLTNY
                     PSQTGQDLANRFATAGVDVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKA
                     GFTITDVNPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDTHGRGFYPACGALC
                     AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETI
                     LVLSGVSSLDDIDSMPFRPSWIYPSVAEIDVI"
     gene            21529..23193
                     /gene="asnB"
                     /locus_tag="IT892_003074"
     CDS             21529..23193
                     /gene="asnB"
                     /locus_tag="IT892_003074"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HAP3136262.1"
                     /translation="MCSIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNA
                     ILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEV
                     ILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVAS
                     EMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALED
                     SVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAARRVEDQERSEAWWPQLHSFAVGLP
                     GSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMS
                     RKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKA
                     MSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHILRECFEAYLPASVAWRQK
                     EQFSDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPL
                     PSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVHQSAYK"
BASE COUNT         5855 a         5883 c         5872 g         5960 t
ORIGIN      
        1 tcatcattaa ataaattaag attgatcatt ttttattgat caccttcaca gttcaaccgt
       61 atttcctgga tagaatatct tcaccttcat tcacatcagg aaaggtaaat taaatggaaa
      121 ataacagccg cactatgccc catataaggc ggaaaactca tattatgaag tttgctcatc
      181 gcaatagctt cgactttcac ttcttcaatg cccgttagtc taccgactaa gggcacttca
      241 gcgtacaggt cttcctgact ctctgtatta caggcatatg cctgtattcc gcagtgctca
      301 ttctctgtta acccttgtat tatcagccac ctgactggta agggtttctg cattctgaaa
      361 aaagcaatct acctgattta tttatcagcg gggtaacttt gcttttttcc ggcacgatcg
      421 atttctcatt cgagaaattg aggacctgct attacctaaa ataaagagat gaaaaatgtc
      481 aaaattaaaa attgcggtta gtgattcttg cccggactgt tttaccacgc agcgagaatg
      541 tatctacatt aatgaaagtc gtaatatcga tgtggcggca atagttttat cgctcaacga
      601 tgttacatgc ggaaaactcg atgaaatcga tgccacgggt tatggcatcc cggtatttat
      661 tgctactgaa aatcaagaac gtgtacccgc agagtatttg ccccgtattt cgggtgtctt
      721 tgagaattgc gaatcgcgac gagaatttta tggtcgccag ttagaaaccg ctgccagcca
      781 ttatgaaact caactgcgcc cacctttctt ccgcgcactg gtcgattatg tcaatcaagg
      841 taacagcgcg tttgattgcc ctggtcatca gggcggcgaa tttttccgtc gccatccggc
      901 ggggaatcag tttgtggaat actttggtga ggcgctgttc cgtgccgact tgtgcaacac
      961 cggtttatct ggaaacggca cgtaacccgt atggctttat cggtggcatt gatgcgcact
     1021 gttttgaaga aagttacctg cgtgagctga tcgcggaagt cgcaccgcag cgggcaaaag
     1081 aggctcgtcc tttccgcctc gctgtgattc agttaggcac ctacgacggt acgatttata
     1141 acgcccgcca agtggtggat aaaattggtc atctgtgtga ctacatcctg tttgactcag
     1201 catgggtcgg ctatgaacag tttattccga tgatggcgga ctgttcgccg ctgttgctgg
     1261 atcttaatga gaacgatccg ggtattctgg ttacgcaatc tgtgcataaa caacaggctg
     1321 gtttttctca gacttcacaa attcataaaa aagacagcca catcaaaggg caacagcgtt
     1381 atgtaccgca caaacgcatg aacaacgcct ttatgatgca cgcctccacc agcccgttct
     1441 atccgctgtt tgccgcactg gatatcaacg ccaaaatgca tgaaggtgtc agcggtcgta
     1501 atatgtggat ggattgtgtg gtaaatggca ttaatgcccg caaactgatc ctcgataact
     1561 gtcagcatat tcgtccgttc gtacctgaac tggtggatgg taaaccctag cagtcgtatg
     1621 aaacagcgca aattgcggtt gatctgcgct tcttccagtt tgtaccaggg gaacactggc
     1681 attcttttga aggctatgca gagaatcaat actttgtcga tccatgcaaa ctgttgctga
     1741 caaccccagg tattgatgca cgtaacggcg aatatgaagc gttcggtgta cccgcgacga
     1801 ttcttgctaa cttcctgcgc gaaaatggcg tagtgccgga aaaatgcgat cttaactcca
     1861 tcctcttcct gctgactccg gcagaagata tggccaaact tcagcaactt gttgccctgc
     1921 tggtacgctt cgaaaaactg cttgagtccg acgcgccatt agcagaagtg ctaccttcca
     1981 tctacaaaca gcatgaagag cgctacgccg gttataccct gcgtcagttg tgtcaggaaa
     2041 tgcatgattt gtatgcccgc cacaacgtga aacaactgca aaaagagatg ttccgtaagg
     2101 agcacttccc acgcgtcagc atgaatccgc aagaagccaa ctacgcctat ttacgcggtg
     2161 aagtggaact ggttcgtctg ccggatgcag aaggccgtat cgctgccgaa ggtgcgcttc
     2221 cttatcctcc gggtgtgctg tgtgttgttc cgggtgaaat ctggggtggt gctgttctgc
     2281 gttacttcag cgctctggaa gaagggatca acctgctgcc aggttttgca ccggagctgc
     2341 agggtgtcta tatcgaagaa catgatggtc gtaagcaagt ttggtgctat gtcatcaagc
     2401 ctcgtgatgc gcaaagcacc ctgttgaaag gggaaaaatt atgagtcagg ctaaatcgaa
     2461 caaaatgggc gtcgttcagt taaccatact gacgatggtc aacatgatgg gctccggtat
     2521 catcatgctg ccgacaaagc ttgccgaagt cgggacaatc tcaattatct cctggctggt
     2581 gacagccgta ggctcaatgg cactggcatg ggcattcgca aaatgcggta tgttcagccg
     2641 taaatcaggc ggtatgggcg gttatgccga gtatgctttc ggtaaatccg gtaactttat
     2701 ggcgaactat acctacggcg tctcactgct gattgctaac gtcgcgattg ctatttcggc
     2761 ggttggttac ggcaccgaac tgctcggcgc gagtttgtcg ccagtgcaga ttggtcttgc
     2821 gaccatcggg gtgctgtgga tttgtaccgt ggctaacttt ggtggtgcgc gcattaccgg
     2881 gcaaatcagt agcattaccg tgtggggggt cattattccg gtcgtcggtc tgtgcattat
     2941 tggctggttc tggtttagcc cgacgctgta cgttgattcc tggaatccgc atcatgcacc
     3001 gttcttcagt gcggtaggtt cttccatcgc tatgacgctg tgggcttttc ttggtctgga
     3061 gtctgcgtgt gcgaatactg atgtagtgga aaacccggaa cgtaatgtgc caatcgcggt
     3121 actcggcggt acgttaggtg cggcggtgat ttatatcgtc tccaccaacg tgattgccgg
     3181 gattgtgcca aatatggagc tggcaaattc aacggcacca tttggtctgg ccttcgcgca
     3241 gatgttcacg ccggaagtgg gtaaagtcat tatggcgctg atggtgatgt cctgctgcgg
     3301 ttcgctactt ggctggcagt tcaccattgc ccaggtgttt aaatcttcat ctgatgaagg
     3361 ctacttccct aaaattttct cccgtgtaac caaagtggat gcaccggtgc agggaatgtt
     3421 gaccattgtg attattcaga gtggattggc actgatgacc attagcccgt cgctaaacag
     3481 tcagttcaac gtgctggtta acctggccgt ggtgaccaat atcattccgt atattctgtc
     3541 aatggcggca ttagtcatta ttcagaaggt cgctaatgtg cccccctcaa aagcgaaagt
     3601 tgcaaacttt gttgcttttg ttggcgcgat gtatagcttt tatgcgctgt actcatccgg
     3661 ggaagaagcc atgctgtacg gttccatcgt gaccttcctt ggttggacac tgtatggtct
     3721 ggtatcacca cgctttgaac tgaaaaataa acacggttaa taaaacaaag taaaaaaggg
     3781 cgattgaatg atcgcccttt ctgtttgttg gcaaatagtt cgttatttat gccgcatccg
     3841 gcagatgtag ggtctaaacg cgatcgaaca cagcaactat ttgcgtaatt atatggggca
     3901 tctgcgacaa aaactggaac aggatccggc ccggcctcgc cattttatta ctgaaaccgg
     3961 tattgggtat cggtttatgc tttgaaaaaa gtggcaatgt atggataaag tcatttttta
     4021 ttcaaatata aggaacttaa tatttaaaaa atgttccata caattcctca tcataaatga
     4081 caccgtagca cacaaggagc aagtagcgat gcgtgaaatg aatcagttag taaatactga
     4141 agattcagcc tggccaataa tccagaactg gttaaaagac gccacaaacc ataccgaact
     4201 cttaccggtt aataaagatt tagccgaaac cgcactttat caattacagg tgacaacaaa
     4261 atcaccgatg ggtgcgcttg tctatggctc cggaggtctg ctgattgata atggttggtt
     4321 acgcatagca ggatctggtc acccccggtt gccacgagat ccagtaagtt ggacacaacg
     4381 ccctgaattc gcaggcgtgc gggctttacc catcgctgac gatgtcgcag ggggaatttt
     4441 tgctcttaat ggtggcgatc ttggggaaga tactggctgc gtttattatt ttgcgccaga
     4501 tacgctgaat tgggaaagtc tggaagttgg atattctgag tttcttcagt gggcattatc
     4561 cggtgattta gataccttct atgaaaatgt acgatggcag caatggcgag aagacgtaat
     4621 aaaattatcg gcaacggaag ccttcacgtt ctaccctttc ttatgggtac aaagtgaaga
     4681 agcaagaaca agaaaagtta tttcgcttac tgaactctgg gaaatgcagt atcaaatgaa
     4741 agaaacattc acgcaataag acatgttcag gtccgggttt cattcccgga ctcactattt
     4801 taatgtgtat ttatcgcttt caattcttgc tggcaatttt ctgactggca gcgtcgtaac
     4861 tcaataatcc cgacatgcat catcgagcca aaaaatccgc tttcgctgac ataatcctca
     4921 ttgactatcg gtcgagtgcc gggcttgccc tggcaaaccc gcataaaaaa tgaggtgtag
     4981 cattgccaac cgggatttaa accgaccttt tcttgtgctg acatattatg aagataagta
     5041 agttcttttt cgttcccgcc tgacaactgc cagcggcggg tattatcagg taagttatca
     5101 ccacggcaat ttgtcttaca ccggaaaggt gcaatattta ccgcaatgct acccgttaat
     5161 cctctggttt tatctttagg ggtcagtaac cagtcgccag ctaatgatga ttgttcaggt
     5221 tgggcgcatg cagtcagcag taatgtggcg gtaattagtg acactatgac gaccagactc
     5281 ctgttggtct tcattgggat ttccttgagc tactcagttt gttgacaaag tgttcgttgt
     5341 ttttgccgga tgcggcgtga acgccttatc cggcctacaa aatcgcttaa attcaatata
     5401 ttgcaccatc ctcgtaggcc tgataagcgt agcgcatcag gcaattctgt gtttgtcata
     5461 cgtaaaaaag ggcgatcttg cgaccgccct ttttttatta aatgtgttta cgcgtttttc
     5521 agaacttcgc taacaatctc aaccgcttct ttctcaatct gcttgcgatg ttcttcaccg
     5581 aggaagcttt cgcagtagat cttatatgcg tcttccgtgc ctgacggacg cgcggcgaac
     5641 cagccgttgt cagtcatcac tttcagaccg ccaatagaag caccgttgcc cggagcagca
     5701 gtcaggcgcg cggtgatcgg gtcacctgcc agggtgctgg cgctcaccat ttccggagac
     5761 agcttagaca gcgccgcttt ttgtgcggaa gtcgcagctg cctgcaaacg gttgtagctc
     5821 ggcgcaccaa agcgttttgc cagttcgttg tagtgttcct gcgggttctt accggtgaca
     5881 gcggtgattt ccgccgccag cagacacatg atgatgccgt ctttgtcggt ggaccacggc
     5941 gtgccgtcga aacgcaggaa ggaagcccct gcactctctt cgccgccaaa gccgaagctg
     6001 ccgtcgaaca gaccatcgac aaaccatttg aaacctaccg ggacttctac cagtttacgg
     6061 cccaagtcgt tgaccacacg gtcgatcatc gcagatgaaa ccagcgtttt accgacggca
     6121 acatctttgc cccactgcgg acgatgctgg aacaggtaat tgattgccac cgccaggtag
     6181 tggttcggat tcatcaaacc tgccggagtg acgataccgt gacggtcata atccgggtcg
     6241 ttagcaaacg ccagatcgaa cttatcacgc agtgccagca ggcccgccat cgcacactcg
     6301 gaggagcagt ccatacggat cgcgccgtct ttatcaaggt gcataaagcg gaaggtttga
     6361 tcgacctgat cgttaacgat agtcaggttg aggttgtaat actcgccaat acgcttccag
     6421 tattcgatac cggaaccgcc cagcggatca acgcccagcg tcaggcccgc tttctgaatc
     6481 gcggccatat caacgatatc ggccagacct tccacgaacg gctgcaccag atcctgctct
     6541 ttcacatgac cggatgccat cgcttcgtcg agggagatac gcttcacgcc tttcaggcca
     6601 tcggccagca gtgcgttggc cctgtcttcc accactttag tgacgttggt atcagccggg
     6661 ccaccatttg gcggattgta tttgattcca ccatcttccg gcgggttatg ggacggtgta
     6721 atcacgatac cgtctgccag cgggccacct tttttattgt gaaccaggat ggcattggaa
     6781 acggcaggcg tcggggtgaa gccattgttt tcctgcacaa tgacatcaac gccgttcgct
     6841 gccagcactt ccagaacgga aatgaatgca ggttcggaca gggcgtgagt atctttaccc
     6901 acatagcaag ggccagtgat gccgtttttc gcacgttctt cagcaattgc ctgagcgatc
     6961 gccagaatgt gcggctcgtt aaagctgtgg cgcgctgcac tgccacggtg accggaagta
     7021 ccgaatttca ccgcgtgctc cgcattccct gcttctggtt tcagtacata atattgcgcc
     7081 gtcagttggg cgacgttaat caaatcactc tgttgtgcag gttggcctgc acgattgtgg
     7141 attgccattg ctttgtcctt tgtctgcaac gttttagata gttccgcaaa ccttctcaat
     7201 caattccgcc gggaattgca tcgactgcat gatgtgttcg atcatgctgc atttacggcc
     7261 ggtgttggtg ttggtgatca cccaatacgg cgtgcctggc acatgtttcg gcttggtctg
     7321 attaccattt ttcagcagcg tttgttcatc tgccgcaaag taaacgcgtg tacgaccgtg
     7381 caacgattcc gttgcttcgg caaacgcctg ggcgtcaaga gaatatagtg tagacaacag
     7441 cagcataaag cgattgaccg ctcgcttttg ctctgcgtat tcatccgaaa gcagaagttc
     7501 acgcattgcg cgaaccttgt ctttaatcgt tttgaccggc ttcgcttcga cgatagcagg
     7561 tgacgcaacg cgaacctctt tcgtcaccgg agcagcaggc tgtgatgcgg cggaaaattt
     7621 caacatacgc cgtaaaatgt cggatgcgct ctcgccgata tgcttagtgt ggctggcaat
     7681 atagctgtag agttcatcat caacttcaat cgttttcatc ttaatccagt gcagtgtctt
     7741 agctgaatac aagtcgccag gagtatatga ataaatcccg gcagcggata gcgtcaagcc
     7801 tggcttgcag aaaaactcgg aataaacctt atttgttgca gccctgtggc acaatggtca
     7861 acataatacc ctaacccgac aacgcgaaaa aaagaacttt gccatgaaat tgaatatccg
     7921 cgcgcaaact gcacaaaacc agcacaataa ttctcccatc gttcttgtcc acggtctgtt
     7981 tggcagcctc gacaaccttg gcgtactggc tcgcgatctg gtaaacgatc acaatatcat
     8041 ccaggttgat atgcgtaacc acggtctttc accgagagat ccggtaatga attacccggc
     8101 gatggcgcag gatcttgttg atactctgga tgcacagcag atcgacaaag caacatttat
     8161 cggtcactcc atgggcggta aagcggtaat ggcacttact gcactagcct ccgatcgcat
     8221 cgataaactg gtggcgatcg atatcgcgcc ggtcgactat cacgtacgcc gtcatgatga
     8281 gatttttgcg gctatcaacg cggtcagtga atcggacgca caaactcgcc agcaagcagc
     8341 agcaataatg cgccagcatc ttaatgaaga aggggtgatt cagtttctgc tgaaatcttt
     8401 tgttgacggg gagtggcgct ttaacgtgcc ggtattgtgg gatcagtatc cgcatattgt
     8461 aggttgggag aaaatcccgg catgggatca ccctgccctg tttatccctg gcggcaattc
     8521 tccgtatgtt agcgagcagt accgtgatga tttactggct caatttccac aggcacgggc
     8581 gcatgtgatt gcaggcgcgg gtcactgggt ccatgctgaa aaaccggatg cggtattacg
     8641 cgctatccgt cgctatctca atgattaacg caactgatta aaaacccagc gtccgcgtcg
     8701 ctttccgcgc gtgggcgttg gcgtgactca tcgcgctgat gtattatggc gcgctatcca
     8761 tccgggcaga ggcctggctg attgtttccc ccgaagtcac caagatcatg gccaaagaac
     8821 aaacggaccg tacgacatta gatctgttcg cgcacgagcg tcgaccggga cgaccgaaaa
     8881 ctaatccgct ttcgcgcgat gaacagctgc gtattaataa acgcaaccag ctaaaacgcg
     8941 acaaagtacg tggccttaag cgtgtcgaac tgaagctgaa cgcggaagct gtcgaggcgc
     9001 tgaacgagct ggcggagtcg cgcaatatga gccgtagcga actgatcgaa gagatgttaa
     9061 tgcagcaact ggcggcgctg cgtagtcagg gcatcgttta aatttccact ttcatgtagc
     9121 acagtgtgca gtcctgctcg tttgctgatt ccgcaagact gcctgttctg ctatgattgc
     9181 ctttatccgt gggcaatttt ccacccccat ttcaataagt ttcaagaggt tatttcactc
     9241 atggctatca ctggcatctt tttcggcagc gacaccggta ataccgaaaa tatcgcaaaa
     9301 atgattcaaa aacagcttgg taaagacgtt gccgatgtcc atgacattgc aaaaagcagc
     9361 aaagaagatc tggaagctta tgacattctg ctgctgggca tcccaacctg gtattacggc
     9421 gaagcgcagt gtgactggga tgacttcttc ccgactctcg aagagattga tttcaacggc
     9481 aaactggttg cgctgtttgg ttgtggtgac caggaagatt acgccgaata tttctgcgac
     9541 gcattgggca ccatccgcga catcattgaa ccgcgcggtg caaccatcgt tggtcactgg
     9601 ccaactgcgg gctatcattt cgaagcatca aaaggtctgg cagatgacga ccactttgtc
     9661 ggtctggcta tcgacgaaga ccgtcagccg gaactgaccg ctgaacgtgt agaaaaatgg
     9721 gttaaacaga tttctgaaga gttgcatctc gacgaaattc tcaatgcctg atgtgatgcg
     9781 gcgtagactc atgtctacgc cgtattaata gataatgcca atcaaaataa ttgctacaaa
     9841 tttgtaactt ttgctgttgt acctgtacaa tgtcccggtg ttcaagtggc cttgccgttg
     9901 taaatgtaag ctgtgccacg tttttattaa caatatttgc cagggacttg tggttttcat
     9961 ttaggcgtgg caattctata atgatacgca ttatctcaag agcaaattct gtcacttctt
    10021 ctaatgaagt gaaccgctta gtaacaggac agattccgca tgactgataa caataccgcc
    10081 ctaaagaaag ctggcctgaa agtaacgctt cctcgtttaa aaatcctgga agttcttcag
    10141 gagccggaca accatcacgt cagtgcggaa gatttataca aacgtctgat cgatatgggt
    10201 gaagaaattg gtctggctac ggtatatcgc gtactgaacc agtttgacga cgctggtatc
    10261 gtcacccgcc acaattttga aggcggtaaa tccgtatttg aactgacaca gcaacatcac
    10321 cacgatcacc tgatctgcct cgactgcggc aaggttatcg aatttagtga tgattccatc
    10381 gaagcgcgtc agcgtgaaat tgccgcaaaa catggcattc gcctgactaa ccacagtctc
    10441 tatctttacg gtcactgtgc cgaaggcgat tgccgcgaag atgaacatgc gcacgaaggc
    10501 aaataagcca gcctgaacga gaaaagccaa cctgcgggtt ggctttttta tgcaagggaa
    10561 ataagaaaag cgagagttac agctctcact tatttgttat tactgcgtat ttcctgccag
    10621 actttatcac aatcggcttt caccgcctga tcatttccgg tttgcgttgc acgcagacac
    10681 tgctgataat ccagtacgcg tacactttcc tggtcggcaa actgctgatg ttgtttctct
    10741 ttcttcagca cgtttaacac gctctggcag gcttcaattt tttctggcga accttgtgcg
    10801 gtgttgatac aggcgctgta tgcctctttc agacgactgt cttcctgtgg cgcggttgat
    10861 tgcgcacaag ctaccagccc cgatgccatt atggcgatga gaatcagttt tttcatagca
    10921 aattcctcaa acgtgcggca ggcacaaaac ctgccgcgtc gggcatcaga agatggtgaa
    10981 tggtgcgatt accataaatt tcacgtcacg ctcatcctgg aagatgttgc cgtaaccacc
    11041 gccccagctt gggatgtcgg agtggttgtc gtattcggtg aaatgcagtt tgaacatcgt
    11101 gcctttggcg cgaccgtcct gaatggtata gaccgcatcc aggctgtagg cagactcttc
    11161 aatagtccgg tttttgtcgt agtacgcatc cggattgctc tgccaggtcg caggtttagc
    11221 atcccatgcg taaacgtagg aagcgccgat ggcgaagcct ggaagattcc agtttttcag
    11281 gtcatacatc gcaccgaaga agaccgcttt ttcgccgttg gcgttgaagt cagaacggtt
    11341 atcccaccag atatccaggc gaccgtttga ggaagcgtag gttggagtca tacgttgcag
    11401 gaagtatccc tgctgaccgt cagccttaac ccaggtgcct tcgaggcgca aatccactac
    11461 gtcagccgcc cggtaaccaa aggtcaacgc ttgcagccag gcggtgccgt cataaaggtc
    11521 gttgacgctg cgatcgtcaa ctttatctcg ggtaccgtag aactggtagc tggtggttaa
    11581 cgggctaccg gcgatatcaa atttgtagct ggctttggca aaatattgat cgatataccc
    11641 ttccgcctga ccaaatgccg cttccagtac gaagttattt ttgaagtcgt atttcgcccc
    11701 aaaggagtgc agataatcaa ctttggtggt tttatcgttc tgataaaact catccatttc
    11761 cagatgccac ggcgctttgt attcgttggt ccacatgtag gagaaactca acgcaccagc
    11821 atcgccgtaa tcaaaattcg ccccggcttc cgccccctga taagtacctg gcataaagct
    11881 ccagtgcggc gctaacagcg tttgaccagt tggctgaatg taacctgccc tcgcccaaac
    11941 cggaccgtat ttaaatttgg ccgcagcttt atacaggctt ataccgcttt tgtcgccgga
    12001 ccagtcttcg tcataggctt tattactttt tgaaaacgcg atttcgttcg ggtgggagct
    12061 gtcgccgttt tccgccattt caatcgccgt aaacgcagca atatcaaggc cgaacatatc
    12121 agcagcataa ccggactgaa aatcgaggtt ggcattccag gtggagtgag aaaggttggt
    12181 tttgtatttg tcgccgtcgg taacatcttt acggtcgcgt tcacgctgcc agtaatagat
    12241 accgccggtt aaggttgaat cgtcgatgaa tccttcggcg cgagcctccg gcattgccat
    12301 aaagcccgac attgctgtaa caccggcgat agccagcgcc agcgtactac gtttgccact
    12361 aaacgtacgc atgggttaat cctctttgac gtataaattg ctgcaccaaa ggtgaacagc
    12421 gaaaaaataa aaattaaaaa agtagcgttg agaaaagtct cgctgactac aggaacagac
    12481 tatttttcgc gacgcgaatt atcaatctct ttctgtaacc agaatgtaag aacatgagca
    12541 accgcacata ttttgatgat ttttgttaca aggcttaagt ttgcggttga aaggcttgca
    12601 gaagaataaa agcgtgaaat tccagcaaga tgaaagcggt tacattttat ttaattatgt
    12661 tttgttattt taaatttatt ttatggataa attgcgaagc ggaattaatt cgcgaagaaa
    12721 agcagaaaaa acgccgctga acgcggcgtt ttggattgtt tgctgtttct tgccggatgc
    12781 ggcgtgaacg ccttatccgg cctacaaaag cacgcaaact caatatattg cagagatcat
    12841 gtaggcctga taagcgtagc gcatcaggca atttagcgtt tgaaactgtt tgtctgttcc
    12901 ttgccggatg cgacgtaaac gccccatccg gcatagcgaa acttaaaatt actcgcctac
    12961 tttcgcccag gtatcacgca gcccaacggt gcggttaaat accggttttt ccgccgtaga
    13021 atggcggcta tcgaggcaga agtaaccttc acgctcaaac tggaatgctt tacccgcaac
    13081 cgcatctttc agcgacggtt cagcaaagcc ctgtttgatc accagcgatt ccgggttaat
    13141 caccgacagg aaatcatccg cagcacctgg gttaggcacg ctgaacagac ggtcatacaa
    13201 acggatttca accggcagcg catgtgccgc gctcacccag tgaataacac ctttgacttt
    13261 acgaccatct gccggatctt tgcttaaggt atcggcgtca taagtacaga agatggtggt
    13321 gatattacct tcggcatctt tctcgacgcg ttctgcctta atcacataag cattacgcag
    13381 acgcacttct ttacccagca ccagacgttt gtactgcttg ttagcttctt cgcggaaatc
    13441 ggcgcgatca atccaaatct caccgctaaa cggcacctga cggctgccca tttccggttt
    13501 gttcggatgg ttcggcatgg taaccatttc gccttcgccc tgatagtttt cgataaccag
    13561 tttcaccgga tcgataaccg ccattgcgcg cggcgcattt tcgttgagat cttcacggat
    13621 gcaggattcc agcgacgcca tctcaatggt gttgtcctgc ttggtcacgc cgatgcgttt
    13681 gcagaactca cgaatagaag ccgcagtgta accacgacga cgcagaccgg aaatggtcgg
    13741 catacgcggg tcatcccagc cttcaacgtg cttgtcggtc accagcaggt tcaacttacg
    13801 cttggacatc acggtgtatt ccagattcag gcgcgagaac tcatactggc gcgggtgaac
    13861 aggaatcgtg atgttgtcca gtacccagtc gtacagacga cggttgtcct ggaactcaag
    13921 cgtacacaga gagtgcgtaa taccttccag ggcatcgctg atgcagtggg tgaagtcgta
    13981 catcgggtag atgcaccact tgttgccagt ctggtggtgt tcagcaaatt taatacggta
    14041 cagcaccgga tcgcgcatca cgataaacgg tgaagccatg tcgattttcg cacgcaggca
    14101 ggctttacct tcttcaaaac caccggcacg cattttttcg aacagcgcca ggttctcttc
    14161 aacgctgcgg tcgcggtacg ggctgttttt acccggttgc gtcagggtgc cgcggtattc
    14221 gcggatctgt tccggcgtca gttcatcaac gtacgccagg cctttattga tcagttcgat
    14281 cgcataggcg tggagctgat caaaataatc ggaggagtaa cggacgttac cagaccagtg
    14341 aaaacctaac cactctacgt cgtttttgat cgactcaaca tactcgatat cttcttttac
    14401 cgggttagtg tcgtcgaaac gcaggttgca ctggccttta tagtcctggg cgatcccgaa
    14461 gttcaggcag atagatttcg catggccaat atgcagatag ccattcggct ccggcgggaa
    14521 acgggtgtgt actgtggtgt gcttaccact ggccagatct tcatcgatga tctgacggat
    14581 aaagttagtc gggcgggctt ctgcctcact catcgtggat tcctcaaagc gtaaacaacg
    14641 tataacggcg tatgatctta taagcgggac aggctgacaa ctgttagttt tttaaaattg
    14701 ataatctaac aaggattatg gggatgattg atgaaaaaaa aagcggcaga gaagatctcc
    14761 accgcttgtc attgttggat gcgacgctca agcgtcgcat caggcataaa gcagattact
    14821 ttttgatttc atacagcggt gtttgacccg ccacaacatg gccctgagct ttaatgatca
    14881 agccactgaa atcgtcgata ttgctgcaaa ccaccgggct aatcatcgag cgggcgttag
    14941 cgttcaggta atccagatcc atttccagaa tcggttgccc tgcgcttacc tgcgcaccct
    15001 cttccaccag acgtttaaag cctttacctt ccagcgctac ggtgtcgata cccatatgga
    15061 cgacgatctc cgcgcctttt tcggtttcca ggcagaacgc gtggttggtg ttgaagattt
    15121 tcacgattgt ccctgcggct ggtgatacga cgattttatc tgtcggtttc accgccacac
    15181 cgtcacccac cgctttgctg gcgaatgctt cgtcaggaac ctgatccagt gccacgacat
    15241 caccggtaat cggcgatacc agctccgcga tagataccgc gtttggtaca gcctgcggtt
    15301 ttgctacagg cgcggcagtt gccggagttg cttcagctga cgcagcggct accggaccac
    15361 gggcaacgac tttcttcatc gcatcgccga tggattctgc tttcgcgcca acaatcacct
    15421 gaatagtctg tttgttcagt ttcactaccc cagaagcacc cagacgttta cacatcgtat
    15481 cgttaacgcg ggcagagtca gccactgtaa ggcgcagacg ggtgatacag gcgtcaatcg
    15541 ctttcaggtt gtcagtgccg ccaaccgcag caatatagtt ggttgccagt tgagtcagac
    15601 cttcttcagt gttgctgttg gcttcttcag taacgatctc gtcttcttta tcttcacgac
    15661 ccggcgtttt caggttgaac atgcggataa ccaaactgaa caccacgaag tagatagcga
    15721 agaagataac gcccatcacc agcagcatcc agacgttctg gctggcggcc ggcaggttat
    15781 acatcaacgc gtagtcgata gcccccgcag agaaagagaa gcccgcgtgg atacccagca
    15841 gcgttgccac aaacaggctg ataccggtca gcagtgcgtg caggaggtac agcagcggag
    15901 caaggaacat gaacaggaat tccagcggct cagtcacacc ggtcaggaac gcagtaacag
    15961 caacagaaag cagcataccg ccaaccatcg gacgacgctc tttcggtgct gcgaagtaca
    16021 tcgccagcgc cgcacccggc agaccgaaca tcatgatcgg gaagaagccg gacatgaaca
    16081 tccccgcggt gccgtcaccg gcatagaagc ggttaatgtc accgtggaaa accgtacccg
    16141 ccgcgttggt gaattcacca atctggaacc aggcgatggt gttcagtacc tgatgcagac
    16201 cggttgggat cagcagacgg ttgatgaaac caaagatacc ggaacccagc gcgcccgcag
    16261 aaacgatcca ctcgccgcct gcatggatag cgtgctgtac cggcggccag acgtaaccaa
    16321 aaatggccgc cagcaccagg cagaagaatc cggtggcaat cggcacaaag cgtttgccgc
    16381 cgaagaagct caggaagtcc ggcagtttaa tatcggacca acggttatag gctgcgccac
    16441 caaccagacc ggtaatgata cccgccagta cacccatgtt aatttctggg ttgatggtca
    16501 ccatcgcttt ggttaacaca aagtaaccta ccgcacccgc cagcgccgcc gcaccagcgc
    16561 tgtctttcga ccagctggat gccacaccga tggcgaagat taatgcgagg ttatcaaaaa
    16621 tcgcaccgcc cgcctgggca ataaacgcaa cgttaagtaa atctggctga ccgaatcgca
    16681 gcaacagtgc cgccaccggc agcaccgcga tagggagctg taacgcccta ccgagtcgct
    16741 ggaaaaaacc taaaatattc atcttattcc ccctacgaga accctatttg gctcgtttca
    16801 agccgtattt ttattttgct gcaaattgta ctgccgatgt tctgtaatca gattgttaga
    16861 tcatctgcta cagagtgtgt gaaaatttaa ttcgtatcgc aaattaaacg cgtgtctttt
    16921 gtgagttttg tcaccaaata tcgttatcat cactcccttt tactggctaa accagaaaac
    16981 ttattttatc attcaaaaaa tcaggtcgga ttgacgcctg tctgcgcaaa tccaggttac
    17041 gcttaaagat gcctaatccg ccaacggctt acattttact tattgaggtg aataatgaga
    17101 ctgatccccc tgactaccgc tgaacaggtc ggcaaatggg ctgctcgcca tatcgtcaat
    17161 cgtatcaatg cgttcaaacc gactgccgat cgtccgtttg tactgggcct gccgactggc
    17221 ggcacgccga tgaccaccta taaagcgtta gtcgaaatgc ataaagcagg ccaggtcagc
    17281 tttaagcacg ttgtcacctt caacatggac gaatatgtcg gtctgccgaa agagcatccg
    17341 gaaagctact acagctttat gcaccgtaat ttcttcgatc acgttgatat tccagcagaa
    17401 aacatcaacc ttctcaacgg caacgccccg gatatcgacg ccgagtgccg ccagtatgaa
    17461 gaaaaaatcc gttcttacgg aaaaattcat ctgtttatgg gcggtgtagg taacgacggt
    17521 catattgcat ttaacgaacc ggcgtcttct ctggcttctc gtactcgtat caaaaccctg
    17581 actcatgaca ctcgcgtcgc aaactctcgt ttctttgata acgatgttaa tcaggtgcca
    17641 aaatatgccc tgactgtcgg tgttggtaca ctgctggatg ccgaagaagt gatgattctg
    17701 gtgctgggta gccagaaagc actggcgctg caggccgccg ttgaaggttg cgtgaaccat
    17761 atgtggacca tcagctgtct gcaactgcat ccgaaagcga tcatggtgtg cgatgaacct
    17821 tccaccatgg agctgaaagt taagacttta agatatttca atgaattaga agcagaaaat
    17881 atcaaaggtc tgtaattgtt atccctgccc tggctccttg ctcagggcaa tattttttaa
    17941 aatcgggggt cagaatgtat gcattaaccc agggccggat ctttaccgac cacgaatttc
    18001 ttgatgacca cgcggttgtt atcgctgatg gcctgattaa aagcgtctgt ccggtagcgg
    18061 aactgccgcc agagatcgaa caacgttcac tgaacggggc cattctctcc cccggtttta
    18121 tcgatgtgca gttaaacggc tgcggcggcg tacagtttaa cgacaccgct gaagcggtca
    18181 gcgtggaaac gctggaaatc atgcagaaag ccaatgagaa atcaggctgt actaactatc
    18241 tgccgacgct tatcaccacc agcgatgagc tgatgaaaca gggcgtgcgc gttatgcgcg
    18301 agtacctggc aaaacatccg aatcaggcgt taggtctgca tctggaaggt ccgtggctga
    18361 atctggtaaa aaaaggcacc cataatccga attttgtgcg taagcctgat gccgcgctgg
    18421 tcgatttcct gtgtgaaaac gccgacgtca ttaccaaagt gaccctggca ccggaaatgg
    18481 ttcctgcgga agtcatcagc aaactggcaa atgccgggat tgtggtttct gccggtcact
    18541 ccaacgcgac gttgaaagaa gcaaaagccg gtttccgcgc ggggattacc tttgccaccc
    18601 atctgtacaa cgcgatgccg tatattaccg gtcgtgaacc tggcctggcg ggcgcgatcc
    18661 tcgacgaagc tgacatttat tgcggtatta ttgctgatgg cctgcatgtt gattacgcca
    18721 acattcgcaa cgctaaacgt ctgaaaggcg acaaactgtg tctggttact gacgccaccg
    18781 cgccagcagg tgccaacatt gaacagttca tttttgcggg taaaacaata tactaccgta
    18841 acggactttg tgtggatgag aacggtacgt taagcggttc atccttaacc atgattgaag
    18901 gcgtgcgtaa tctggtcgaa cattgcggta tcgcactgga tgaagtgcta cgtatggcga
    18961 cgctctatcc ggcgcgtgcg attggcgttg agaaacgtct cggcacactc gccgcaggta
    19021 aagtagccaa cctgactgca ttcacacctg attttaaaat caccaagacc atcgttaacg
    19081 gtaacgaggt cgtaactcaa taagagaaag tatgacacca ggcggacaag ctcagatagg
    19141 taatgttgat ctcgtaaaac agcttaacag cgcggcggtt tatcgcctga ttgaccagta
    19201 cgggccaatc tcgcggattc agattgccga gcaaagccag cttgcccccg ccagcgtaac
    19261 caaaattacg cgtcagctta tcgaacgcgg gctgatcaaa gaagttgatc agcaggcctc
    19321 caccgggggc cgccgcgcta tctccatcgt caccgaaacc cgcaatttcc acgcaatcgg
    19381 cgtacggctt ggtcgtcatg acgccaccat cactctgttt gatctcagca gcaaagtgct
    19441 ggcagaagaa cattacccgc tgccggaacg tacccagcaa acgctggaac atgccctgtt
    19501 gaatgccatt gctcagttta ttgatagcta ccagcgcaaa ctgcgcgagc tgatcgcgat
    19561 ttcggtgatc ctgccagggc ttgttgaccc ggacagcggc aaaattcatt acatgccgca
    19621 tattcaggta gaaaactggg ggctggtaga agctctggaa gaacgtttta aagtgacctg
    19681 tttcgttggt cacgatatcc gtagtctggc gctggcggag cactacttcg gtgcaagtca
    19741 ggattgcgaa gactccattc tggtgcgtgt ccatcgcgga accggggccg ggattatctc
    19801 taacgggcgc atttttattg gccgcaacgg caacgtcggt gaaattggcc atattcaggt
    19861 cgaaccgctg ggtgaacgct gccactgcgg caactttggc tgcctggaaa ctatcgctgc
    19921 caacgctgcc attgaacaac gggtgttgaa tctgttaaag cagggctacc agagccgcgt
    19981 gccgctggac gactgcacca tcaaaactat ctgcaaagcc gcgaacaaag gcgatagtct
    20041 ggcgtcggaa gtaattgagt atgtcggtcg tcatctgggt aaaaccatcg ccattgctat
    20101 caacttattt aatccgcaaa aaattgttat tgccggtgaa atcaccaaag ccgataaagt
    20161 gctgctccct gctattgaaa gctgcattaa tacccaggcg ctgaaggcgt ttcgcactaa
    20221 tctgccggtg gtacgttctg agctggatca ccgctcggca atcggcgctt ttgcgctggt
    20281 aaaacgcgcc atgctcaacg gtattttgct ccagcatttg ctggaaaatt aatgtgcttt
    20341 tatagtggcg cttattgttg tcaatattct gggtagtcca tgaccattaa aaatgtaatt
    20401 tgcgatatcg acggcgtgct gatgcacgat aacgtcgccg taccgggtgc agcggaattt
    20461 ttgcacggga ttatggataa aggcctgccg ctggtgttgc tgaccaacta tccttcgcag
    20521 actgggcaag atctggcgaa ccgctttgcc accgcaggtg tcgatgtacc tgacagcgtg
    20581 ttttatacct ctgcgatggc gactgccgat ttcctgcgtc gccaggaagg caagaaagcg
    20641 tatgtggtgg gcgaaggcgc actgattcat gaactgtaca aagccggttt cactattacc
    20701 gatgtgaacc ctgatttcgt gattgttggc gaaacgcgtt cctacaactg ggacatgatg
    20761 cataaagcag cctatttcgt cgctaacggt gcacgtttta tcgccaccaa tccggacacc
    20821 cacgggcgcg gtttttatcc cgcttgtggc gcgttgtgtg cagggattga gaaaatctcc
    20881 gggcgcaaac cgttctatgt tggtaagccc agcccgtgga tcatccgcgc agcattaaac
    20941 aaaatgcagg cgcattcgga agaaacggtg attgtcggcg ataacctgcg taccgatatt
    21001 ctggccggct tccaggcagg tctggagacg attctggtgc tttctggtgt ttcgtcgctc
    21061 gacgatatcg acagtatgcc tttccgcccc agctggattt acccgtcagt cgctgaaatc
    21121 gacgttatct gaatagcaac cacgtctgcg gacgtggttg gctctgatga caaacgccaa
    21181 actgcctgat gcgctacgct tatcaggcct acgcagctcc tgcaatatat tgaattttca
    21241 tgcttttgta ggccggataa ggcgttcacg ccgcatccgg catgaacaaa tcgcactttg
    21301 tcagcaattt ggcccccgta aaatataaac attcaataaa acccgctaaa aattatcgat
    21361 tcatcaataa atatatcctc acaccagacc ttttttcacc aatcgacaat caccattacg
    21421 ttttttattt tttcaccgcc aaatcgcttg cgcacagtgc tgctttgcgg cattttttta
    21481 aacaagcaaa cacaacaagc aacaaatacc aggttaacgg agaaggttat gtgttcaatt
    21541 tttggcgtat tcgatatcaa aacagacgca gttgagctgc gtaagaaagc cctcgagctg
    21601 tcacgcctga tgcgtcatcg tggcccggac tggtccggta tttatgccag cgataacgcc
    21661 attctcgccc acgaacgtct gtcaattgtt gacgttaacg cgggggcgca acctctctac
    21721 aaccaacaaa aaacccacgt actggcggta aacggtgaaa tctacaacca ccaggcattg
    21781 cgcgccgaat atggcgatcg ttaccagttc cagaccgggt ctgactgtga agtgatcctc
    21841 gcgctgtatc aggaaaaagg gccggaattt ctcgacgact tgcagggcat gtttgccttt
    21901 gcactgtacg acagcgaaaa agatgcctac ctgattggtc gcgaccatct ggggatcatc
    21961 ccactgtata tggggtatga cgaacacggt cagctgtatg tggcctcaga aatgaaagcg
    22021 ctggtgccag tttgccgcac gattaaagag ttcccggcgg ggagctattt gtggagccag
    22081 gacggcgaaa tccgttctta ctatcatcgc gactggttcg actacgatgc ggtgaaagat
    22141 aacgtgaccg acaaaaacga gctgcgtcag gcactggaag attcagttaa aagccatctg
    22201 atgtctgatg tgccttacgg tgtgctgctt tctggtggtc tggattcctc aattatttcc
    22261 gctatcacca agaaatacgc agcccgtcgc gtggaagatc aggaacgctc tgaagcctgg
    22321 tggccgcagt tacactcctt tgctgtaggt ctgccgggtt caccggatct gaaagcagcc
    22381 caagaagtgg caaaccatct gggcacggtg catcacgaaa ttcacttcac tgtacaggaa
    22441 ggtctggatg ccatccgcga cgtgatttac cacatcgaaa cttatgatgt gaccactatt
    22501 cgcgcttcaa caccgatgta tttaatgtcg cgtaagatca aggcgatggg cattaaaatg
    22561 gtgctgtccg gtgaaggttc tgatgaagtg ttcggcggtt atctttactt ccacaaagca
    22621 ccgaatgcca aagaactgca tgaagagacg gtgcgtaaac tgctggccct gcatatgtat
    22681 gactgcgcgc gtgccaacaa agcgatgtca gcctggggcg tggaagcacg cgttccgttc
    22741 ctcgacaaaa aattccttga tgtggcgatg cgtattaacc cacaggataa aatgtgcggt
    22801 aacggcaaaa tggaaaaaca catcctgcgt gaatgttttg aagcgtatct gcctgcaagc
    22861 gtggcctggc ggcagaaaga gcagttctcc gatggcgtcg gttacagttg gatcgacacc
    22921 ctgaaagaag tggctgcgca gcaggtttct gatcagcaac tggaaactgc ccgcttccgc
    22981 ttcccgtaca acacgccaac ctctaaagaa gcgtacttgt atcgggagat ctttgaagaa
    23041 ctattcccgc ttccgagcgc cgctgagtgc gtgccgggcg gtccttccgt cgcttgttct
    23101 tccgctaaag cgatcgaatg ggatgaagcg ttcaagaaaa tggacgatcc gtctggtcgc
    23161 gcggttggtg ttcaccagtc ggcgtataag taagaaatgc gaaacagccc cggtgaaatc
    23221 cggggctgtt tcagttattg aggtgcttgt tgattctgat atgcagtaag gaaatgttcc
    23281 gggtttgcca catcactgtt tgacaactca tcactgtagg ccagtatttc atagattaat
    23341 ttcccaccac tattgttaaa ttccgaattt catcctgtat gacaaaagaa tggctgtagg
    23401 gtgggaaaaa acacaaagta aacaataatt gacgaatata gcgccacgct gttcgcaacc
    23461 taaccaaaca gtcactttcg agcaattttc cttgaaaaag aggttgacgc tgcaaggctc
    23521 tatacgcata atgcgccccg caacgccgat aaggtatcgc gaaaaaaaag
//
LOCUS       DACAOP010000072        23322 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.072, whole genome shotgun sequence.
ACCESSION   DACAOP010000072 DACAOP010000000
VERSION     DACAOP010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23322
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.072"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..1065
                     /gene="xylE"
                     /locus_tag="IT892_003075"
     CDS             <1..1065
                     /gene="xylE"
                     /locus_tag="IT892_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose transporter XylE"
                     /protein_id="HAP3136263.1"
                     /translation="IGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIFGQLLVYCV
                     NYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLMSRGKQEQAEGI
                     LRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVGVIVIGVMLSIFQQFVGINVVL
                     YYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIG
                     MFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEIFPNAIRGKALAIAVA
                     AQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETKGKTL
                     EELEALWEPETKKTQQTATL"
     gene            complement(1109..1519)
                     /gene="psiE"
                     /locus_tag="IT892_003076"
     CDS             complement(1109..1519)
                     /gene="psiE"
                     /locus_tag="IT892_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
                     /protein_id="HAP3136264.1"
                     /translation="MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLAD
                     VLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLII
                     VDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE"
     gene            complement(1645..1788)
                     /locus_tag="IT892_003077"
     CDS             complement(1645..1788)
                     /locus_tag="IT892_003077"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136265.1"
                     /translation="MFQRNIVDFSRIAGGWESPEWVIFELPALVRFVLPDAPPGAAYP
                     AYG"
     gene            1789..2067
                     /locus_tag="IT892_003078"
     CDS             1789..2067
                     /locus_tag="IT892_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136266.1"
                     /translation="MKRNLIKVVKMKPYFAALMLSVSVLPAYAGPLGTADKADLPQSN
                     VSSPMMAQSLRQPDLQPISTDRKTECFRLYTPDRKPGVNCVPDGSTGH"
     gene            complement(2114..4210)
                     /locus_tag="IT892_003079"
     CDS             complement(2114..4210)
                     /locus_tag="IT892_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HAP3136267.1"
                     /translation="MKKRHLLSLLALGISTACYGETYPAPIGPSQSDFGGVGLLQTPT
                     ARMAREGELSLNYRDNDQYRYYSASVQLFPWLETTLRYTDVRTRQYSSVEAFSGDQTY
                     KDKAFDLKLRLWEESYWLPQVAVGARDIGGTGLFDAEYLVASKAWGPFDFTLGLGWGY
                     LGTSGNVKNPLCSASDKYCYRDNSYKQAGSIDGSQMFHGPASLFGGVEYQTPWQPLRL
                     KLEYEGNNYQQDFAGKLEQKSKFNVGAIYRVTDWADVNLSYERGNTFMFGVTLRTNFN
                     DLRPSYNDNARPQYQPQPQDAILQHSVVANQLTLLKYNAGLADPQIQAKGDTLYVTGE
                     QVKYRDSREGIIRANRIVMNDLPDGIKTIRITENRLNMPQVTTETDVASLKNHLAGEP
                     LGHETTLAQKRVEPVVPQSTEQGWYIDKSRFDFHIDPVLNQSVGGPENFYMYQLGVMG
                     TADLWLTDHLLTTGSLFANLANNYDKFNYTNPPQDSHLPRVRTHVREYVQNDVYVNNL
                     QANYFQHLGNGFYGQVYGGYLETMFGGAGAEVLYRPLDSNWAFGLDANYVKQRDWRSA
                     KDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVV
                     GGYATITNVSKEEYGEGDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGR
                     KFQLYDMTSDRSVNFR"
     gene            complement(4210..4947)
                     /locus_tag="IT892_003080"
     CDS             complement(4210..4947)
                     /locus_tag="IT892_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HAP3136268.1"
                     /translation="MIKQTIVALLLSVGASSVFAAGTVKVFSNGSSEAKTLTGAEHLI
                     DLVGQPRLANSWWPGAVISEELATAAALRQQQALLTRLAEQGADSSADDAAAINALRQ
                     QIQALKVTGRQKINLDPDIVRVAERGNPPLQGNYTLWVGPPPSTVTLFGLISRPGKQP
                     FTPGRDVASYLSDQSLLSGADRSYAWVVYPDGRTQKAPVAYWNKRHVEPMPGSIIYVG
                     LADSVWSETPDALNADILQTLTQRIPQ"
     gene            complement(4944..5582)
                     /locus_tag="IT892_003081"
     CDS             complement(4944..5582)
                     /locus_tag="IT892_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418451.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbF family lipoprotein"
                     /protein_id="HAP3136269.1"
                     /translation="MKRPALILICLLLQACSATTKELGNSLWDSLFGTPGVQLTDDDI
                     QNMPYASQYMQLNGGPQLFVVLAFAEDGQQKWVTQDQATLVTQHGRLVKTLLGGDNLI
                     EVNNLAADPLIKPAQIVDGASWTRTMGWTEYQQVRYATARSVFKWDGTDTVKVGSDET
                     PVRVLDEEVSTDQARWHNRYWIDSEGQIRQSEQYLGADYFPVKTTLIKAAKQ"
     gene            complement(5696..5938)
                     /locus_tag="IT892_003082"
     CDS             complement(5696..5938)
                     /locus_tag="IT892_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136270.1"
                     /translation="MKKVLYGIFAISALAATSAWAAPVQVGEAAGSAATSVSAGSSSA
                     TSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ"
     gene            complement(6437..8086)
                     /gene="pgi"
                     /locus_tag="IT892_003083"
     CDS             complement(6437..8086)
                     /gene="pgi"
                     /locus_tag="IT892_003083"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAP3136271.1"
                     /translation="MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSAT
                     FDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALR
                     NRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDL
                     GPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTN
                     AHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSA
                     IGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEA
                     ILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLI
                     HQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKD
                     PATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQW
                     GVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG"
     gene            8611..9960
                     /gene="lysC"
                     /locus_tag="IT892_003084"
     CDS             8611..9960
                     /gene="lysC"
                     /locus_tag="IT892_003084"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-sensitive aspartokinase 3"
                     /protein_id="HAP3136272.1"
                     /translation="MSEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGI
                     TNLLVALAEGLEPGERFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAA
                     ALATSPALTDELVSHGELMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDIA
                     ALAELAALQLLPRLNEGLVITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVD
                     IWTDVPGIYTTDPRVVSAAKRIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFV
                     GSSKDPRAGGTLVCNKTENPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILAR
                     HNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALI
                     GNDLSKACGVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGEDAEQVVQKLHSNLFE"
     gene            10213..10485
                     /locus_tag="IT892_003085"
     CDS             10213..10485
                     /locus_tag="IT892_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3811 domain-containing protein"
                     /protein_id="HAP3136273.1"
                     /translation="MALPRITQKEMTEREQRELKTLLDRARIAHGRVLTNSETNSIKK
                     DYIDKLMVEREAEAKKARQLKKKQAYKPDPEASFSWSANTSTRGRR"
     gene            complement(10618..11490)
                     /gene="rluF"
                     /locus_tag="IT892_003086"
     CDS             complement(10618..11490)
                     /gene="rluF"
                     /locus_tag="IT892_003086"
                     /EC_number="5.4.99.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="HAP3136274.1"
                     /translation="MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGD
                     QVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFP
                     IGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPIL
                     GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPL
                     GEWRDLTDDELIDLFKLIENSSSEVKPKAKAKPKTAGIKRPVVKMEKTAEKGGRPASN
                     GKRFTSPGRKKKGR"
     gene            11702..12391
                     /gene="pepE"
                     /locus_tag="IT892_003087"
     CDS             11702..12391
                     /gene="pepE"
                     /locus_tag="IT892_003087"
                     /EC_number="3.4.13.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepE"
                     /protein_id="HAP3136275.1"
                     /translation="MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQ
                     TWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGL
                     LAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTN
                     ALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGE
                     EAVPLEAGHRF"
     gene            complement(12482..14113)
                     /locus_tag="IT892_003088"
     CDS             complement(12482..14113)
                     /locus_tag="IT892_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HAP3136276.1"
                     /translation="MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKK
                     PLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALAPALVIVLGADVGTALMARILTF
                     DLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
                     QVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANL
                     GSGLLAMLNNSAANAAARRVALGSLLFKLVGSLIILPFVHLLAETMGKLSLPKAELVI
                     YFHVFYNLVRCLVMLPFVDPMARFCKTIIRDEPELDTQLRPKHLDVSALDTPTLALAN
                     AARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEE
                     LAEEESRRWAEIIEMSLNLEQASDIVERMGSEIADKSLAARRAFSLDGLKELDALYEQ
                     LLSNLKLAMSVFFSGDVTSARRLRRSKHRFRILNRRYSHAHVDRLHQQNVQSIETSSL
                     HLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY"
     gene            complement(14333..18016)
                     /gene="metH"
                     /locus_tag="IT892_003089"
     CDS             complement(14333..18016)
                     /gene="metH"
                     /locus_tag="IT892_003089"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAP3136277.1"
                     /translation="MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFAD
                     WPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAE
                     INFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLV
                     AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDA
                     SGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAG
                     LPNAFGEYDLDADTMAKQIREWAQAGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLP
                     EIPVACRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVE
                     NGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWDVIEKGLKCIQG
                     KGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKIL
                     TEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVS
                     FSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRR
                     DDGTERLLELAEKYRGSKTDDTANAQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEA
                     RQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASK
                     EQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNA
                     DLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVY
                     VQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDF
                     AFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVE
                     AQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLR
                     QQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMV
                     KALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHT
                     EKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYA
                     RRKGMSVTEVERWLAPNLGYDAD"
     gene            18216..19040
                     /gene="iclR"
                     /locus_tag="IT892_003090"
     CDS             18216..19040
                     /gene="iclR"
                     /locus_tag="IT892_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate bypass operon transcriptional
                     repressor IclR"
                     /protein_id="HAP3136278.1"
                     /translation="MVAPIPAKRGRKPAVATAPATGQVQSLTRGLKLLEWIAESNGSV
                     ALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWAIGAHAFMVGSSFLQSRNLL
                     AIVHPILRNLMEESGETVNMAVLDQSDHEAIIIDQVQCTHLMRMSAPIGGKLPMHASG
                     AGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQTRKRGYSFDDEEHAL
                     GLRCLAACIFDEHREPFAAISISGPISRITDDRVTEFGAMVIKAAKEVTLAYGGMR"
     gene            19357..21543
                     /locus_tag="IT892_003091"
     CDS             19357..21543
                     /locus_tag="IT892_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ShET2/EspL2 family type III secretion system
                     effector toxin"
                     /protein_id="HAP3136279.1"
                     /translation="MITRIPRSSFSANINNTAQTNEHQTLSELFYKELEDKFSGKELA
                     TPLLKSFSENCRQNGRHIFSNKDFVIKFSTSVLQADKKEITIINKNENTTLTQTIAPI
                     FEKYLMEILPQRSDTLDKQELNLKSDRKEKEFPRIKLNGQCYFPGRPKNRIVCRHIAA
                     QYINDIYQNVDYKPHQDDYSSAEKFLTHFNKKCKNQTLALVSSRPEGRCVAACGDFGL
                     VMKAYFDKMESNGISVMAAILLVDNHALTVRLRIKNTTEGCTHYVVSVYDPNVTNDKI
                     RIMSESKENIKHYSLMDFMNVDYSLLKWSNDHVINQSVAIIPALPKEQLLMLKGSVDE
                     ITPPLSPATMNLLMAIGQNHQLTQLMIQLQKMPELHRTEMLTAYNSINLPGLYLAINY
                     GNADIVETIFNSLSETGYEGLLSKKNLMHILEAKDKNGFSGLFLAISRKDKNVVTSIL
                     NALPKLAATHHLDNEQVYKFLSAKNRTSSHVLYHVMANGDADMLKIVLNALPLLIRTC
                     HLTKEQVLDLLKAKDFYGCPGLYLAMQNGHSDIVKVILEALPSLAQEINISASDIVDL
                     LTAKSLARDTGLFMAMQRGHMNVINTIFNALPTLFNTFKFDKKNMKPLLLANNSNEYP
                     GLFSAIQHKQQNVVETVYLALSDHARLFGFTAEDIMDFWQHKAPQKYSAFELAFEFGH
                     RVIAELILNTLNKMAESFGFTDNPRYIAEKNYMEALLKKASPHTVR"
     gene            complement(21512..23248)
                     /gene="aceK"
                     /locus_tag="IT892_003092"
     CDS             complement(21512..23248)
                     /gene="aceK"
                     /locus_tag="IT892_003092"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HAP3136280.1"
                     /translation="MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ
                     QAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESF
                     FNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDL
                     PLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSG
                     TLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILP
                     GKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRV
                     FKVIKDRFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMEL
                     LLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA
                     ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSV
                     SPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRR
                     QRFSVRYGEMLF"
BASE COUNT         5664 a         6080 c         5830 g         5748 t
ORIGIN      
        1 attggcgttg gtttagcctc aatgctctcg ccaatgtata ttgcggaact ggctccagct
       61 catattcgcg ggaaactggt ctcttttaac cagtttgcga ttattttcgg gcaactttta
      121 gtttactgcg taaactattt tattgcccgt tccggtgatg ccagctggct gaatactgac
      181 ggctggcgtt atatgtttgc ctcggaatgt atccctgcac tgctgttctt aatgctgctg
      241 tataccgtgc cagaaagtcc tcgctggctg atgtcgcgcg gcaagcaaga acaggcggaa
      301 ggtatcctgc gcaaaattat gggcaacacg cttgcaactc aggcagtaca ggaaattaaa
      361 cactccctgg atcatggccg caaaaccggt ggtcgtctgc tgatgtttgg cgtgggcgtg
      421 attgtaatcg gcgtaatgct ctccatcttc cagcaatttg tcggcatcaa tgtggtgctg
      481 tactacgcgc cggaagtgtt caaaacgctg ggggccagca cggatatcgc gctgttgcag
      541 accattattg tcggagttat caacctcacc ttcaccgttc tggcaattat gacggtggat
      601 aaatttggtc gtaagccact gcaaattatc ggcgcactcg gaatggcaat cggtatgttt
      661 agcctcggta ccgcgtttta cactcaggca ccgggtattg tggcgctact gtcgatgctg
      721 ttctatgttg ccgcctttgc catgtcctgg ggtccggtat gctgggtact gctgtcggaa
      781 atcttcccga atgctattcg tggtaaagcg ctggcaatcg cggtggcggc ccagtggctg
      841 gcgaactact tcgtctcctg gaccttcccg atgatggaca aaaactcctg gctggtggcc
      901 catttccaca acggtttctc ctactggatt tacggttgta tgggcgttct ggcagcactg
      961 tttatgtgga aatttgtccc ggaaaccaaa ggtaaaaccc ttgaggagct ggaagcgctc
     1021 tgggaaccgg aaacgaagaa aacacaacaa actgctacgc tgtaatcttc ctgtccagca
     1081 cgccgcgcca tttcggcgtg ctgacttttt actcccgctt cagccgtttc gaattacaca
     1141 gccacagggt gatcaccagt aacaggatcg cagccgagta gatcaacaca tccagtggcg
     1201 atttatgatc gacgatgatc aagcgcacaa tggcggtgat cccaatatag acaaagtaac
     1261 gtagcgggaa gtgaaaaccg gactgaaagt acttcacaat cagcgcgata aattcgaaat
     1321 agagaaagta aaccaccagt ccttctacca gctcatattt gctggtttgt tctggcgcga
     1381 acagcacatc agccagatgc accgtttctt tgccgaggaa gacaaccaaa atcaggccga
     1441 ggcacagcag gccaagattg agtacggtct gcaaaatggt ggagataaac tccacgcgcg
     1501 gacgagagag tgacgtcata gcagtacctc cttcacagtg gcgagcttcc tgtataacgc
     1561 aaaaatgtga cggagatcta tattttttgt gtatgttttg ttcaacctgg atttggagcg
     1621 cgcctccacc aaagccggat atacctaccc gtaggccgga taagccgcgc ctggcggcgc
     1681 atccggcaag acaaaccgca ccaaagccgg taattcaaaa atcacccatt caggtgattc
     1741 ccagccacca gcaatgcgcg aaaaatcgac aatgttcctc tggaacaaat gaaacgtaac
     1801 ctgataaagg tggtaaaaat gaagccttat tttgctgctt tgatgttatc agtctctgtt
     1861 cttcctgctt atgctggtcc gctcggtact gctgataaag ccgacctacc gcaaagcaat
     1921 gtctccagcc caatgatggc ccagtcgctc aggcaaccag acctgcaacc gatatcgacg
     1981 gacaggaaga cagaatgttt tcgcctttac acaccagatc gcaaaccggg agtgaactgc
     2041 gttcctgatg gctcgacagg ccattaagaa tgaaggtgcc agtgagtgcg aaaactggca
     2101 cctttcccat gacttagcgg aaattgacgc tacggtcgct ggtcatgtca tacaactgga
     2161 acttacgccc aagttgctga ccaccgtcac gcgtcagcgg cgtccagcca atcgccgcac
     2221 ggctgcgtgt cgggccagac gagaagagat ccaacggtac cgagacatac acgcctttgg
     2281 tgaagtcccc ttcgccgtac tcctctttcg aaacattagt gatcgtggca tagccaccca
     2341 ccaccacgcc gctatcaaag cgtttggcga tctccagcgt gccgccttta tcccctgcca
     2401 gatactgccc gacgctggct ttaactaaca catcctgagc gaaagatggc gtccagtagg
     2461 cggtcagatg tccggttttc acgctgtagt cggtgaattt catcatatct tttgcactac
     2521 gccagtcgcg ctgtttaacg tagttggcat ccagaccaaa cgcccagttg ctgtccagcg
     2581 ggcgatacaa cacttctgcc cccgcaccgc caaacatggt ttcgagataa ccaccgtaga
     2641 cctgaccgta gaagccgttg cccagatgct ggaagtagtt ggcttgcagg ttattcacat
     2701 agacatcgtt ctgcacatac tcgcgcacat gggtacgcac gcgcggtaag tgcgagtcct
     2761 gcggaggatt agtgtagtta aacttgtcgt agttgttggc aagatttgca aacaggctgc
     2821 cggtggtcag cagatggtcc gtcagccaca aatctgccgt tcccatcacg cccagctgat
     2881 acatgtaaaa gttttccggg ccaccgaccg actggttcag caccggatcg atatggaaat
     2941 caaagcgtga tttgtcgata taccagccct gctcggtgga ctgcggaacc actggctcga
     3001 cgcgtttttg cgccagcgtc gtttcgtggc ccaacggctc tccggcgaga tgatttttca
     3061 ggctggcgac atcggtttcc gtcgtcacct gcggcatgtt aaggcgattt tccgtaatgc
     3121 ggatcgtttt gatcccatcc ggcagatcgt tcatcacgat ccgattcgca cggatgatcc
     3181 cttcgcgcga atcacgatat ttcacctgct cgccggtaac atacagcgta tcgcctttcg
     3241 cctggatctg tggatcggca agtccggcat tgtatttcaa cagcgttaac tgattcgcca
     3301 ccaccgaatg ctgcaaaatg gcatcctgcg gctgcggttg atattgcggg cgggcgttat
     3361 cgttgtaaga cgggcgcaga tcgttaaagt tggtgcgcaa cgtaacgcca aacataaagg
     3421 tgttgccacg ttcatagcta aggttaacgt cggcccaatc ggtaacgcga taaatcgcac
     3481 cgacgttaaa cttacttttt tgctccagct tcccggcaaa atcctgctga taattattgc
     3541 cttcatactc cagtttcagg cgcagcggtt gccagggcgt ctggtattcc acgccgccaa
     3601 acagtgaggc aggaccgtgg aacatctggc taccgtcgat agatcccgcc tgtttgtagc
     3661 tgttatcgcg atagcaatat ttatcactgg ctgaacagag cggatttttc acattaccgc
     3721 tggtgcccaa atatccccag cccaggccga gcgtaaaatc gaacggcccc caggctttgc
     3781 tggcaacaag atattccgca tcaaacagcc ccgtaccgcc gatatcccgc gcaccaaccg
     3841 ccacttgcgg cagccagtaa ctctcttccc acaaacgcag tttgagatcg aaggctttat
     3901 ctttatacgt ttgatcgcca gagaacgctt cgacgctgct gtactgccgg gtgcgcacgt
     3961 cggtgtagcg cagcgttgtt tccagccacg ggaagagttg cactgaagct gagtaataac
     4021 ggtactgatc gttatcgcga tagttcagac tcaactcccc ttcccgtgcc atacgcgcgg
     4081 tgggcgtttg taataatcct acgccaccga aatccgactg cgacggacca atgggcgcag
     4141 gatatgtttc gccgtagcaa gctgtgctaa tgcccagcgc cagtaagcta agcagatgtc
     4201 tttttttcat tattgaggta tccgctgcgt cagagtctga agaatgtcgg cgttaagggc
     4261 atcaggcgtc tcactccaga cggagtccgc gaggccaaca taaataatgc tgccgggcat
     4321 cggctctacg tgacgcttgt tccagtaagc caccggcgct ttttgcgtgc gtccgtccgg
     4381 gtaaaccacc cacgcgtagc tgcgatccgc accgctgagc aggctctggt cagagagata
     4441 gctcgccacg tcgcgacctg gagtgaatgg ctgcttgcca ggacggctga taagcccgaa
     4501 caacgtgacc gtggacggcg gtggtccgac ccacagcgtg tagttgccct gcaacggcgg
     4561 gttaccgcgt tcggcaacgc ggacgatatc gggatcaaga ttgatttttt gcctgcccgt
     4621 cactttcaac gcctgaattt gctggcgtaa ggcgttaatc gcagcggcat cgtcggcgct
     4681 ggaatctgcg ccctgttctg ccagccgtgt cagcaacgcc tgctgctgac gcaatgctgc
     4741 cgccgttgcc agctcttcgc taatcaccgc accgggccac cagctgtttg ccagccgcgg
     4801 ttggcctacc agatcgatta aatgctctgc gcccgttagc gttttggcct cactgctgcc
     4861 attgctgaac accttgacgg ttcctgccgc gaagaccgat gacgctccca cactcaaaag
     4921 caacgcgaca atagtttgtt taatcattgt tttgccgcct tgatgagagt ggttttcacc
     4981 ggaaaataat ccgcgccgag atactgttcc gactggcgaa tttgcccttc gctgtcgatc
     5041 caatagcggt tatgccagcg cgcctggtcg gtggagactt cttcgtccag cacgcgaacc
     5101 ggggtttcat cgctgccgac tttgacggta tcggtgccat cccatttgaa gactgagcgt
     5161 gcggtggcgt agcgtacctg ctggtactcg gtccagccca tcgtgcgcgt ccagcttgcg
     5221 ccatcaacga tttgtgcggg tttaatcagc gggtcggcag caaggttatt cacttcaatc
     5281 aggttgtcgc cgccgagcag agtcttcacc agacggccat gttgggtaac gagagtagcc
     5341 tgatcctgag tgacccattt ttgttgtccg tcttcagcga aggccagcac cacaaataac
     5401 tgcggcccgc cattaagctg catgtactgg ctggcgtagg gcatattttg aatatcatca
     5461 tccgtcagct gtacgcctgg cgtgccgaac agactgtccc acagtgaatt gcccagctct
     5521 ttagtcgtgg ctgaacaggc ctgtaataac aggcagataa gaatgagtgc aggtcgcttc
     5581 acgactcttc tccagagggg cagaataacc acaccggagt gtggttatgg ttaatccctt
     5641 catacttcta gccacagatg caatgactcg aattattttg gggatacata ctttattact
     5701 gggtactggt ggtcgtggtt gtggtggtcc cggtattaga accatcaccg ccaccggttg
     5761 ccgcaagcgc gacacccacc gccgagctta cggtgctgac gctggtcgcg gaggaactcc
     5821 ccgccgaaac cgacgttgct gccgaccctg ccgcttcgcc cacctgtaca ggtgcagccc
     5881 acgcagaagt cgccgcaagc gcagatatgg caaaaatgcc atacagaact tttttcataa
     5941 caatttccct tcattgaatg aatggagatt tacccaaaaa catttcgggc gggatcgagt
     6001 atacacaact aaagcatgcg aattacggcg cggggaatta gcgatggcgt tttaggataa
     6061 ttggaatgaa tatcaaatat aagtttcaac ttatatttaa ataacaataa aaatcataaa
     6121 cttaaaataa aaacaaaagc aattaatctg cgtattttcc gaaataaaca acgattaaaa
     6181 atctatttta ggattaacct cacggtatga tttccgttaa attacagaca aggggattta
     6241 tctgataaaa aaatgccgac ataacgtcgg cattgttatt aaggttattt aatcaatcgt
     6301 gctatgtatt aattgccgaa tacgatgtac atatcggcat cgacctgtag gcctgataag
     6361 acgcgaccgc gtcgcatcag gcatcggttg ccggatgcgg cgtgaacgcc ttatccggcc
     6421 tacatatcga cgatgattaa ccgcgccacg ctttatagcg gttaatcaga ccattggtcg
     6481 agctatcgtg gctgctgatt tctttatcat ctttcagctc tggcagaata cggttcgcca
     6541 gctgtttacc cagttccacg ccccactggt cgaaggtgaa gatgttcagg atcacgccct
     6601 gagtaaagat tttgtgctca tacagcgcaa tcaacgcacc caggctgaac ggagtgattt
     6661 cacgcagcag gatggagttg gtcgggcggt taccttcgaa tactttgaac ggcaccacgt
     6721 agtcaagcgt tgccggatct ttaccctgat cacgatattc ctgctcaacc acttcgcggg
     6781 atttaccaaa cgccagcgct tcggtctggg cgaagaagtt agacagcagt ttctggtgat
     6841 gatcagagag cgggttatgg gtgatagccg gagcgatgaa atcgcacggt accattttgg
     6901 ttccctggtg gatcagctgg tagaacgcgt gctgaccgtt agtgcctggt tcaccccaga
     6961 taatcgggcc agtctggtaa tccacaacgt taccgttacg gtcaacatac ttaccgttgg
     7021 actccatatt gccctgctgg aagtacgccg cgaaacggtg catatactgg tcatacggca
     7081 gaatcgcttc agtttccgca ccaaagaaat tgttgtacca gatgccaatc agcgccagca
     7141 gtacaggcag gtttttctcg gcaggcgtgg tggagaaatg cttgtccatc gcgtgtgcgc
     7201 cggaaagcag ttcaacgaag ttatcaaagc cgatggagag aacaatcgac aggccaatcg
     7261 ctgaccacaa agagtaacgg ccgccaaccc agtcccagaa ctcgaacatg ttggcagtat
     7321 caataccaaa ctcgccaacg gctttggcat tggtggaaag cgccgcaaag tgttttgcaa
     7381 cgtgtttttc atcacctgcc gctttcagga accagtcacg cgcgctatgg gcgttggtca
     7441 tagtttcctg agtggtgaag gttttagatg ctaccaagaa cagcgtggtt tccgggttta
     7501 cttttttcag cacttccgcg atgtgagtcc catcgacgtt agaaacaaag tgcatgttca
     7561 ggtggttttt gtacggacgc agagcttcgg tcaccatgta tgggccgagg tcagaaccgc
     7621 cgatcccgat gttcactacg tcagtgattg ctttgccggt ataacctttc cactcaccgg
     7681 aaataatcgc ttctgagaag gttttcatct tctccagcac cgcgttgact tccggcatta
     7741 cgtctttgcc atcaaccaaa atcggggtat tgctacggtt acgcagcgct acgtgcagca
     7801 cggcgcggtt ttcagtgcgg ttgatcttct cgccagagaa catcgactta atcgcgcccg
     7861 ccagatcgca ctctttcgcc agatcctgta atttcgccag cgtctcttca gtgatgcggt
     7921 ttttggagta atccaccagc atctgatcgt cgaaggttgc ggagaactta gaaaaacgat
     7981 cgccgtcttt agcaaaaaga tcggcgatcg taacgtcttt catttcatcg aagtgtttct
     8041 gtagtgcctg ccaggcagcg gtctgcgttg gattgatgtt tttcattagc aatactcttc
     8101 tgattttgag aattgtgact ttggaagatt gtagcgccag tcacagaaaa atgtgatggt
     8161 tttagtgccg ttagcgtaat gttgagtgta aacccttagc gcagtgaagc atttattagc
     8221 tgaactactg accgccagga gtggatgaaa aatccgcatg accccatcgt tgacaaccgc
     8281 cccgctcacc ctttatttat aaatgtacta cctgcgctag cgcaggccag aagaggcgcg
     8341 ttgcccaagt aacggtgttg gaggagccag tcctgtgata acacctgagg gggtgcatcg
     8401 ccgaggtgat tgaacggctg gccacgttca tcatcggcta caggggctga atcccctggg
     8461 ttgtcaccag aagcgttcgc agtcgggcgt ttcgcaagtg gtggagcact tctgggtgaa
     8521 aatagtagcg aagtatcgct ctgcgcccac ccgtcttccg ctcttccctt gtgccaaggc
     8581 tgaaaatgga tcccctgaca cgaggtagtt atgtctgaaa ttgttgtctc caaatttggc
     8641 ggtaccagcg tagctgattt tgacgccatg aaccgcagcg ctgatattgt gctttctgat
     8701 gccaacgtgc gtttagttgt cctctcggct tctgctggta tcactaatct gctggtcgct
     8761 ttagctgaag gactggaacc tggcgagcga ttcgaaaaac tcgacgctat ccgcaacatc
     8821 cagtttgcca ttctggaacg tctgcgttac ccgaacgtta tccgtgaaga gattgaacgt
     8881 ctgctggaga acattactgt tctggcagaa gcggcggcgc tggcaacgtc tccggcgctg
     8941 acagatgagc tggtcagcca cggcgagctg atgtcgaccc tgctgtttgt tgagatcctg
     9001 cgcgaacgcg atgttcaggc acagtggttt gatgtacgta aagtgatgcg taccaacgac
     9061 cgatttggtc gtgcagagcc agatatagcc gcgctggcgg aactggccgc gctgcagctg
     9121 ctcccacgtc tcaatgaagg cttagtgatc acccagggat ttatcggtag cgaaaataaa
     9181 ggtcgtacaa cgacgcttgg ccgtggaggc agcgattata cggcagcctt gctggcggag
     9241 gctttacacg catctcgtgt tgatatctgg accgacgtcc cgggcatcta caccaccgat
     9301 ccacgcgtag tttccgcagc aaaacgcatt gatgaaatcg cgtttgccga agcggcagag
     9361 atggcaactt ttggtgcaaa agtactgcat ccggcaacgt tgctacccgc agtacgcagc
     9421 gatatcccgg tctttgtcgg ctccagcaaa gacccacgcg caggtggtac gctggtgtgc
     9481 aataaaactg aaaatccgcc gctgttccgc gctctggcgc ttcgtcgcaa tcagactctg
     9541 ctcactttgc acagcctgaa tatgctgcat tctcgcggtt tcctcgcgga agttttcggc
     9601 atcctcgcgc ggcataatat ttcggtagac ttaatcacca cgtcagaagt gagcgtggca
     9661 ttaacccttg ataccaccgg ttcaacctcc actggcgata cgttgctgac gcaatctctg
     9721 ctgatggagc tttccgcact gtgtcgggtg gaggtggaag aaggtctggc gctggtcgcg
     9781 ttgattggca atgacctgtc aaaagcctgc ggcgttggca aagaggtatt cggcgtactg
     9841 gaaccgttca acattcgcat gatttgttat ggcgcatcca gccataacct gtgcttcctg
     9901 gtgcccggcg aagatgccga gcaggtggtg caaaaactgc atagtaattt gtttgagtaa
     9961 atactgtatg gcctggaagc tatatttcgg gccgtattga ttttcttgtc actatgctca
    10021 tcaataaacg agcctgtact ctgttaacca gcgtctttat cggagaataa ttgcctttaa
    10081 tttttttatc tgcatctcta attaattatc gaaagagata aatagttaag agaaggcaaa
    10141 atgaatatta tcagttctgc tcgcaaacga attcccgtac actgaactct ctggctcact
    10201 gagggcacca tcatggcact cccccgtatt acccaaaaag agatgactga acgcgagcag
    10261 cgtgaactta aaacactgct ggatcgggcg cggattgcgc atggtcgcgt attgaccaac
    10321 tccgaaacca acagcattaa gaaagattac atcgataaat taatggttga gcgtgaggct
    10381 gaagcgaaaa aagcccgcca gttgaagaaa aagcaggctt ataaaccgga tcctgaagcg
    10441 tcatttagct ggtcagcaaa tacgtcgacg cgcggcaggc gctaatccac aatcaacgcc
    10501 tgagattttc actcgtcagt gtgaacacaa ttttcccctc accctaaccc ttttcccgaa
    10561 ggggcgaggg gactgtccgg gcacttttgg gccgttttca tcagtctgag gcgttaatca
    10621 gcgccccttc tttttacgcc ccggcgaggt aaaacgctta ccgttggacg ccgggcgacc
    10681 gcctttttcc gccgtttttt ccatcttaac gactggacgt ttgatgcccg ctgttttcgg
    10741 tttggccttc gctttaggtt ttacctcgga agaggaattt tcaatgagct taaagaggtc
    10801 gattaactca tcgtcggtta aatcgcgcca ttcccccagc ggaatgccgc ttaagctaac
    10861 gttcatgatg cgcgtgcgtt ccagcttttt cacttcatag ccgaaatgct cgcacatgcg
    10921 ccggatctga cggttcagcc cctgcaccag ggtaatgcgg aagacaaacg gcgcttcttt
    10981 tttaactttg cactttttgg tcactgtccc gaggattggc acccccgcac tcatgccgcg
    11041 aataaactcc tcggtaatcg gtttatcgac cgtcaccaga tactctttct catgatcatt
    11101 gccagcacgc aggatcttat tcaccagatc gccgtgattg gtgaggaaaa tcagcccctg
    11161 ggagtcttta tccaggcggc caatcgggaa cacgcgtttg ctgtggttaa cgaaatcgac
    11221 aatgttatcg cgctcgccat cttcggtggt gcttacaata ccaacgggct tgttcagggc
    11281 gataagtacc aaatcttcgg cttcccgagg ttcaatcaac tgaccgttta ctttcacaac
    11341 gtcgccgggt ttcacctgat cgccaatggt ggctcgcttg ccattaagga acacattgcc
    11401 ttgctcgata tagcgatccg cttcgcggcg tgagcaaatt ccgctttcgc tgatgtattt
    11461 atttaaacgg actgatgagt cgggcagcat aaattctcct gtaaaaaacg gaatataccg
    11521 tacctttggg ttgataaaaa atagtcatga gcgaactatt tgttatttcc attggcttga
    11581 attcgttacc tgctcaaatc actttccaga agcaatgtgc gacatcgtga gccatgtcag
    11641 taagtggtta aattcgcagt ggtagcatgc ctcccgtgat ttcttactaa ccggagaagt
    11701 aatggaactg cttttattga gtaactcgac gctgccgggt aaagcctggc tggaacatgc
    11761 actgccgcta attgctgaac agttgcaggg tcgccgctca gcggtgttta tccctttcgc
    11821 tggcgtaacg cagacctggg atgattacac agcgaaaacg gctgcggttc tcgctccgct
    11881 gggtgtttct gtcaccggta ttcatagcgt tgtcgatccc gttgccgcga ttgaaaatgc
    11941 tgagatcgtg attgtcggcg gcgggaatac tttccagttg ctgaaacagt gccgcgagcg
    12001 cgggctgctg gcaccaatta ctgacgtggt taaacgtggc gctctgtata ttggctggag
    12061 cgcaggcgct aaccttgctt gcccaactat tcgtaccacc aacgatatgc cgattgtcga
    12121 tccgcaaggt ttcgatgcgc taaatctgtt cccgctgcaa atcaacccgc acttcaccaa
    12181 cgcgctgccg gaaggccata aaggtgaaac ccgtgagcag cgtattcgcg aactgctggt
    12241 cgtcgcgcca gaactgacga ttattggtct accggaaggt aactggatca cagtgagtaa
    12301 aggtcacgct acgctgggtg gcccgaacac cacttatgtg tttaaggctg gtgaagaagc
    12361 ggttccgctg gaagctggtc accgttttta agtgaattgc cggatgcatg atccggcatc
    12421 ttgttcatag tgcctgatgc gacgcttgac gcgtcttatc aggcctacag gattcacaat
    12481 attaatactc gtcccgtcct tcatcttcat ccggctgttc cagcacactg taagccaccg
    12541 aacaaaacag cgagttcagg cgctgcatat ctcccagtaa gcctaaatgt agcgaactgg
    12601 tttcaatgct ctgcacgttt tgctgatgca ggcgatcgac gtgggcgtgg gaatagcggc
    12661 gattaagaat gcgaaaacga tgtttgctgc gacgcaaacg acgagcgctg gtgacatcgc
    12721 cagagaagaa caccgacatt gccagcttta aattactgag caattgctca tagagcgcat
    12781 ccagttcctt caacccatca agcgaaaatg cccgccgtgc tgccagtgat ttgtcagcaa
    12841 tttcgctgcc catgcgctcg acgatatcgg aggcctgttc aaggttgagc gacatttcga
    12901 tgatctctgc ccagcggcgc gactcttcct ccgccagctc ttcttttggc atccgcgcca
    12961 gatacagctt aatggcggtg tagagaacgt tgatatcatc tgccagctta cgcagctctt
    13021 tctcctgccg tggctcaccg tgcatcactt tattcaaccc ttccatcatc tgttccatgg
    13081 cgtcgccaat gcgcagggtt tcgcgcgcgg cgttcgccag agcaagcgtg ggcgtatcca
    13141 gcgcgctgac atccagatgt ttaggccgta gctgggtatc cagttccggt tcatcgcgaa
    13201 taatcgtttt gcaaaaccgt gccatcgggt caacaaatgg cagcatgacc aggcaacgta
    13261 caaggttgta gaagacgtgg aaatagatca ccagttccgc ttttggcaat gacaacttcc
    13321 ccattgtctc tgccagcaaa tggacaaacg gcaggataat caggctaccc accagcttaa
    13381 acagcagact acccagcgcg acacggcggg ctgcggcatt ggcggcactg ttgttgagca
    13441 ttgccagcag accggaaccg aggttagcac caatcaccag acagagcgcc acggggaagg
    13501 agataatgcc tgcggcggtc agagtcgcgg tcagcagtac agcagcaagg ctggagtagc
    13561 tgataatggc gaacatcgcg ccaatcagcg catccagcag aatatcgccg gtcagcgagg
    13621 caaagatcac ctgaacgccg tttgcctggg tgatcggcgt tacggcctgc acaatcaact
    13681 ccagcgctag caaaatcagc ccaagaccaa taccgacgcg gcccagttgc ccggcgcgtg
    13741 actgtttgcg tccgaggaaa aaaatcacgc cgataaaaat aagtaacggt gacagccagg
    13801 ataagtcgaa ggtgagaata cgcgccatta gcgccgtccc gacatctgca cccagcacaa
    13861 tgaccagagc cggtgcgagg gctaccagat cctgagcgac aaacgaggtc accagcatgg
    13921 tggtggcatt actgctctgt accagtgcgg taacgccgat ccccgcgcaa aaggcgagcg
    13981 gctttttttc gacgctccgg ctaaggacag tacgcaaacg cgcgccgaag acgcgcatta
    14041 cgccggttcg aacaatatga gtcccccaga ccagcagggc gacggcagaa agcaggtgaa
    14101 gcagcgttaa cacgagttca ggttctcctt atcgttatat gttcctgaag caattgaatg
    14161 accaaaggac cggaaacacg ctgactggca tctttactgt gccttttgac attcgttttt
    14221 ccggctaaga ttattccagc ctgtttccag tataagtgtt tcatattaat aaagagacag
    14281 ggcactcatt gagcgccctg tttgttgtaa ggaaaagtga cagatttgtg aatcagtccg
    14341 cgtcataccc cagattcggt gccagccagc gctcaacttc ggtaacgctc atacctttac
    14401 ggcgggcata atcttcaacc tgatcgcgct gaatttgtgc tacagcgtag tacttgctgt
    14461 ccgggtggct gaagtaccaa cccgaaaccg atgcaccggg ccacatggcg aaagattctg
    14521 tgagtttcat gccagtgtgt ttttccactt ccagcagctc ccagatggtg gctttttccg
    14581 tatgttccgg gcaggccgga tagcccggtg ccggacggat gccctggtag ttttcgcgga
    14641 tcagctcttc gttgctgagg ttctcgttcg gcgcatagcc ccagtagact ttacgcacac
    14701 gctcatggag atactccgca aaggcttcgg ctaaacggtc ggcaagcgct ttcaccatga
    14761 ttttgttgta atcatcgtgc tgcgcttcaa aggcatcagc cagtgcgtcc tcttccagcc
    14821 cgccagtcac ggcaaatgcg ccgatgtaat ctgctttacc agaaagcttc ggcgcaacga
    14881 agtcagcgag acagtagtta gcgaagcctg ttttttcggt ctgttgacgc agatggtggc
    14941 tgacgttgat cacatgggta cgcgtttcgt cacggtagat ttcaatgtca tcgcccacac
    15001 ggtttgccgg gaacaggccc accacgccac gcggattcag cgttttctcg gcgcttaatt
    15061 tatccagcat gtcgttggcg tctttaaaca gccgctgcgc ctcaacgccc accacttcat
    15121 cttccagaat gcgcggatac ttcccggcca gcgaccaggt cataaagaac ggtgtccagt
    15181 cgatgtaatt acgcagcgtt tcgatgctgg cttcgacttc ctgcacgccg agacggtgcg
    15241 ccaccggcgg cgtgtaagcc tgccagtcaa aagcgaaatc gttatcgcgc gccgcttcca
    15301 gcgtgaccgg tggtgtgcgc ggtttcttgc gcccgtgctg aatacgtacg gtttcgtact
    15361 ccttgcgggt acgagcgaca aaatcatcac gctgggtatc ggaaagcagc gccgccacca
    15421 caccaacggt acgcgaggca ttctgcacat acaccgtcgg gccgctgtag ttctgctcga
    15481 ttttcaccgc cgtgtgcgct tttgaggtcg tcgcgccgcc aatcagtaac ggaatagtga
    15541 agccctgacg ctccatctct ttcgccacgt taaccatctc gtccagcgac ggcgtgataa
    15601 gccccgaaag gccaatcaga tcagcattca cttctttagc ggtacggaga attttttccg
    15661 caggcaccat aacgccgaga tcgacaattt cgtagttgtt acattgcagc accacaccaa
    15721 cgatattttt accgatgtcg tggacgtcgc ccttcacggt ggcgatcacc atcttgccgt
    15781 tggttttgcc ctgctctttg ctggcttcaa taaacggttc gaggtaggcc accgcctgtt
    15841 tcatgacgcg cgccgatttg accacctgtg gcaggaacat tttcccttcg ccaaacaggt
    15901 cgccgaccac attcatgccg tccatcaacg ggccttcaat cacttcaatc gggcgcgtag
    15961 cctgctggcg ggcttcttcg gtatcctgct cgataaactc ggtaatgcct ttgaccagcg
    16021 agtattccag acgtttattc acttcccacg agcgccactc cgcctgctgg gcgttggcgg
    16081 tgtcgtcggt tttgctgccg cgatatttct cggcaagctc cagtaaacgc tcggtgccat
    16141 cgtcgcgacg attaagaatc acatcttcca ccgcgtcgcg cagttcagcg ggtaggtcgt
    16201 cgtaaatcgc cagttgcccg gcgttgacga tccccatatc catgccattg cgaatagcgt
    16261 agtagaggaa cactgcgtga atggcttcgc gcaccggatc gttgccacgg aacgagaaag
    16321 aaacgttaga tacgccgccg gaaatcagcg cgtgcggcag ttcgcgtttg atgtcttcac
    16381 acgcgccgat aaagtcctgc gcgtagttgt tgtgctcttc aatgccagtt gcgaccgcga
    16441 agatgtttgg gtcgaagatg atatcttctg gcgggaagcc aacctcttcg gtgaggattt
    16501 tgtacgcccg acggcaaatc tcgattttcc gtgcgcgagt atcggcctgt ccctgttcgt
    16561 caaaggccat taccaccact gccgcaccgt agcgacgcaa caatttcgcg tgatggataa
    16621 aggcatcgac gccctctttc atcgagatag agttaacaat gcctttgccc tggatacact
    16681 tcagaccttt ttcaatgacg tcccattttg aggagtcgat cataatcggc acgcgagcga
    16741 tatccggttc accggcaatc agattgagaa aacgcaccat cgccgcttcg gcatcgagca
    16801 tcccttcatc catgttgata tcgataatct gcgcgccgtt ttccacctgt tgacgcgcga
    16861 catccagcgc ctcgctgtat ttctcttctt tgatcaggcg cttgaactta gcggaaccgg
    16921 tgacgttggt gcgttcaccc acgttcacaa acaggctatc ttcgccaatg ttcagcggct
    16981 ccaggccgga caaacggcag gctacgggaa tttccggcag tttgcgcggc gctaatcctt
    17041 ctactgcacg actcatcgct gcaatatgtt gtggcgtggt gccacagcag ccgccgacga
    17101 tattgagaaa acccgcttgc gcccattcac gtatctgttt tgccatcgtg tcggcgtcga
    17161 gatcgtactc accaaaggcg ttgggtagcc cggcgttcgg gtgcgcggtg acgtagcatt
    17221 ccgcaatccg tgacagctcc tgcacgtact ggcgcagttc atcgggcccc agcgcacagt
    17281 tcaggccaaa ggtcagagct tcggcgtggc gcaatgagtt gtaaaatgct tcggtggtct
    17341 gcccggagag cgtgcgcccg gaggcgtcgg tgatggtgcc ggagatcata atcggcagct
    17401 caacgcccag cgcttcaaac tccgttttca ccgcaaatac cgccgctttg gcgttaaggg
    17461 tgtcgaaaac ggtttcaatc aggatcagat ccgcgccacc ttccaccagc gctttggtgg
    17521 actctcgata agccgccacc agcccgtcaa aagtgatatt acgaaatgcc ggatcgttga
    17581 cgtccggaga aatagacgcc gtgcggttgg tcgggccgag aacaccggca acgtagcgcg
    17641 gtttctctgg cgtgcgcgcg gtccactcgt cagcacaagc tcgcgccagt ttcgccgccg
    17701 caaagttgat ttccgccgac agggattcca tctggtaatc cgccatcgca atggtcgtgg
    17761 agttgaaggt gttggtttcg atgatatccg cgcccgcttc aaagtaggcg ttgtggatag
    17821 cggcgatcac ttccggttta ctgagtacca gcaggtcgtt gttgcctttg aggtcgcatg
    17881 gccagtcggc aaagcgttca ccacgaaaat cggcttcgtt cagtcgataa ctctggatca
    17941 tggtgcccat accgccgtcc agcaccagaa tacgttcatt taactgcgca cgcagttgtt
    18001 ccactttgct gctcacactt gctcccgaca cgctcaaccc agatttaata aaaattcaac
    18061 aaaccatact ggcataaacg catctgtggt aaaagcgacc accacgcaac atgagatttg
    18121 ttcaacatta actcatcgga tcagttcagt aactattgca ttagctaaca ataaaaatga
    18181 aaatgatttc cacgatacag aaaaaggaga ctgtcatggt cgcacccatt cccgcgaaac
    18241 gcggcagaaa acccgccgtt gccaccgcac cagcgactgg acaggttcag tctttaacgc
    18301 gtggcctgaa attactggag tggattgccg aatccaatgg cagtgtggca ctcacggaac
    18361 tggcgcaaca agccgggtta cccaattcca cgacccaccg cctgctaacc acgatgcaac
    18421 agcagggttt cgtgcgtcag gttggcgaac tgggacattg ggcaatcggc gcacatgcct
    18481 ttatggtcgg cagcagcttt ctccagagcc gtaatttgtt agcgattgtt caccctatcc
    18541 tgcgcaatct aatggaagag tctggcgaaa cggtcaatat ggcggtgctt gatcaaagcg
    18601 atcacgaagc gattattatc gaccaggtac agtgtacgca tctgatgcga atgtccgcgc
    18661 ctatcggcgg taaattgccg atgcacgctt ccggtgcggg taaagccttt ttagcccaac
    18721 tgagcgaaga acaggtgacg aagctgctgc accgcaaagg gttacatgcc tatacccacg
    18781 caacgctggt gtctcctgtg catttaaaag aagatctcgc ccaaacgcgc aaacggggtt
    18841 attcatttga cgatgaggaa catgcactgg ggctacgttg ccttgcagcg tgtattttcg
    18901 atgagcaccg tgaaccgttt gccgcaattt ctatttccgg accgatttca cgtattaccg
    18961 atgaccgcgt gaccgagttt ggcgcgatgg tgattaaagc ggcgaaggaa gtgacgctgg
    19021 cgtacggtgg aatgcgctga ctttttctgg cgggcagagg caatattctg cccatcatac
    19081 ctgagtggca atagaataag ggtgtctgtt aatcgcattg acgccaaaat aacttaatgt
    19141 catacacttc acacactttt attaactcag cattattttt aaacatcaaa ccacttaatt
    19201 attaacaaaa tcgcaagatc tcattccacc gaaactttta cggctgcatt atgagattga
    19261 gcgatttatg atatttcttt agttgtaatc atattaaatt ttttcactgt tctgatagtt
    19321 aaaattcaag acatcaataa acaatgagat atttaaatga ttactcgtat tcctcgtagt
    19381 tctttctctg caaatattaa taatacagcc cagacaaatg aacaccaaac cctgagtgaa
    19441 ttgttttata aagaactcga ggataaattt tctggcaagg agctggcgac gcctctatta
    19501 aaaagcttct cagagaactg tagacaaaat ggtcgtcata tctttagcaa caaggatttt
    19561 gtcattaaat tttccacgtc cgtcttacaa gctgataaga aagaaattac gataattaat
    19621 aaaaacgaaa acacgacact tactcaaacc attgccccaa tatttgaaaa atacctaatg
    19681 gaaattttac ctcaacgctc agacactctt gataaacaag aattaaacct aaaatcagat
    19741 agaaaagaaa aagaattccc aagaattaaa cttaatggtc aatgttattt tccggggcga
    19801 cccaaaaacc gtatagtatg ccgacacatt gctgcacaat atattaatga tatttatcag
    19861 aatgttgatt acaaacccca tcaagatgat tactcttcag ctgaaaaatt tctcacgcac
    19921 ttcaacaaaa aatgcaaaaa ccagactttg gcgttggttt ccagccgtcc tgaggggcgt
    19981 tgcgttgctg cctgcggtga tttcgggcta gttatgaaag catattttga caagatggaa
    20041 tcaaatggca tcagtgttat ggcagccata ttactggtgg ataaccatgc tttgacggtc
    20101 cggctaagaa taaagaacac aactgaagga tgtacccatt acgtggtttc ggtttatgat
    20161 cctaatgtaa ctaacgataa aataagaatt atgagcgaaa gcaaagagaa tattaaacac
    20221 tattctctga tggattttat gaatgtagat tatagcctcc tgaaatggtc aaatgatcat
    20281 gttattaatc aatctgttgc aataattcca gcacttccga aagaacagct attgatgtta
    20341 aaaggatctg tggatgaaat aacccctcca ttatcacctg caacgatgaa tttgctaatg
    20401 gcaattggtc agaatcacca acttacgcaa ctgatgattc aactccagaa aatgccagaa
    20461 ctacatagaa cagaaatgtt gactgcctat aatagtatta acctgccagg tttatatttg
    20521 gctataaatt atggtaatgc ggatatcgtt gagactattt tcaattcatt gtcagaaaca
    20581 ggatatgaag gattactctc gaaaaaaaat ctcatgcata ttctggaggc aaaagataaa
    20641 aatggttttt ctggattatt tttagcgata tcacgtaagg ataaaaatgt tgtaacctcg
    20701 attctgaacg ccttacctaa actggccgca acacatcatt tagataacga acaagtgtat
    20761 aaattcctga gtgccaaaaa tagaacgtcc agccatgttt tataccatgt tatggcgaat
    20821 ggtgatgccg acatgctgaa aattgttttg aacgcgttac ctttgttaat tcgcacatgt
    20881 catttgacta aagaacaggt actcgatctc ctgaaggcaa aggattttta tggttgccca
    20941 ggactatatc tggcgatgca aaatggacat agcgatatcg tgaaagttat tcttgaagca
    21001 ttgcccagcc tagcccagga aattaacatt tcagcttccg atattgtaga tcttctgacc
    21061 gctaaaagtc ttgcgcgcga cacgggtttg tttatggcca tgcagcgcgg acatatgaac
    21121 gttattaata ctatttttaa cgcattaccc actctgttta atacgtttaa attcgataaa
    21181 aaaaatatga agcccctcct cctggcaaat aattctaatg aatatcccgg tttgttttca
    21241 gcgatacagc ataaacaaca aaatgttgta gagacggttt atcttgcttt atctgaccat
    21301 gcacgcctgt ttggatttac cgctgaagat attatggatt tttggcaaca caaagcccca
    21361 caaaaatact ctgcctttga gttggctttt gaatttggtc accgggttat tgctgaatta
    21421 atccttaata cattaaataa gatggctgaa agctttggct ttacggataa ccctcgatac
    21481 attgcggaga aaaattatat ggaagcttta ctcaaaaaag catctcccca taccgtacgc
    21541 taaatctttg cctgcgccga tacgcataaa catcttccac atgcccttca cgtatgcggt
    21601 tttgtagtgc gcgccagtaa tcagcgcgga acaggtcggc gtgcatctct tcaaacagcg
    21661 gaccaatacg cgggtcggcg catagccagt ggcgaaactc ttccgggaaa acatcgcccg
    21721 gcgagacgct gtaccacggt tcgctggcaa gttcgtcttc cggatagcgc ggcggcggga
    21781 tgtcgcggaa attcacttcc gtcatgtagc aaatttcatc gtaatcataa aaaaccacac
    21841 gcccgtgacg ggtgacaccg aagtttttaa acagcatgtc gccagggaaa atgttagcag
    21901 cggcaagctg gcgaatagcg ttaccgtatt cttcaatggc gtcgcgcaac tgctgacctt
    21961 ccacttgttc cagccagata ttgagcggca ccatccgccg ctcaatataa agatggcgaa
    22021 tcacaatttg ttcgccgaga tcggtgattt tttccgctgc ttcctgaagc agtaattcca
    22081 ttaatgccgg ggaaatatgc cgcttctcca gcacaaagtt ttcaaactcc tgggtgtccg
    22141 ccattcggcc cacgcgatcg tgctctttca ccagttgata gcaggcacga acgtgagcgg
    22201 cagacatctc tttctgcggc gcgaacctgt ctttgatgac tttgaatacc cgatcaaagc
    22261 ccggcagcgt aaacaccaac atcaccattc cacgaatacc cggcgcttca atgaactgct
    22321 cattacagcc ctgtagataa acgagatatt cgcgatagct ttcggttttg gcgtgcttct
    22381 ggcagccgat agccatatac aattcagcgg tggttttacc tggcagaatt tcccgtagcc
    22441 actcgaccag cgctgcgggc agcggcgcat aaaccataaa ataagaacgc gcaaagccaa
    22501 aaacaatgct cgcttcggcg gtcgtcgtca ggcaggtatc aataaataac tcgccgtcgt
    22561 ccgtctggtg gatcggcagc aaaaatggca atgtgccgga aggtgtgatc agtttgccta
    22621 ccagccaggc ggctttattg cggtaaaaca gttcgttcgc cacctgtaaa tgactttccg
    22681 cgaggttgtc tgtccccagc gtttccgtca gatggcgaat aatgtaatgg atgtcacggc
    22741 ttttattctg ccagcgcagg cgcagcggta ggtcgctgat aacgcgcatc agtagagatt
    22801 cccagccgtg atcggggtga aagtctttcg ccagcgggcg gggaatggta cgaaagcggc
    22861 gctctggctg agagctaaag ataaaaagcc gctcgggagt aagcgagcgg tggtcaaata
    22921 accgacagta cacggagtta aaaaagctct ccgcaatctc gaagcgcggg taatccggca
    22981 acagccgggt gtaatgctct ttaacacgta gtaaaaatgc cgcgtccgta ctttggccgt
    23041 tagtaatgca gcgcagttgc tccacgacca aaccaacgtg atgatcgtaa agatggatac
    23101 ggtttttcat cgcctgctgg acagcatgcc agtcggcctg ttcgaaacgc tgctgcgcac
    23161 cggaggtcac ttcgaggaat cgaccatact gagcatcgaa gccttgcaaa atggtttgag
    23221 caatcaataa ttccaggcca cgcggcattt agcgccctca tcaggagcag agaattgccg
    23281 gatgcggcgt aaacgcctta tccagcctac gttcggcaac gg
//
LOCUS       DACAOP010000073        22968 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.073, whole genome shotgun sequence.
ACCESSION   DACAOP010000073 DACAOP010000000
VERSION     DACAOP010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22968
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.073"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..1087
                     /gene="solA"
                     /locus_tag="IT892_003093"
     CDS             <1..1087
                     /gene="solA"
                     /locus_tag="IT892_003093"
                     /EC_number="1.5.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="HAP3136281.1"
                     /translation="SVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYG
                     EGEKYVPLVLRAQTLWDELSRHNEEDPIFVRSGVINLGPADSTFLANVAHSAEQWQLN
                     VEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCP
                     VTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRY
                     SVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVASDGSK
                     AFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASV
                     LGEIAADFAQDKKSDFDLTPFRLSRFQ"
     gene            1135..1248
                     /locus_tag="IT892_003094"
     CDS             1135..1248
                     /locus_tag="IT892_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2770 domain-containing protein"
                     /protein_id="HAP3136282.1"
                     /translation="MRRLLHYLINNIREHLMLYLFLWGLLAIMDLIYVFYF"
     gene            1509..2075
                     /locus_tag="IT892_003095"
     CDS             1509..2075
                     /locus_tag="IT892_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HAP3136283.1"
                     /translation="MSFTNTPERYGVISAAFHWLSAIIVYGMFALGLWMVTLSYYDGW
                     YHKAPELHKSIGILLMMGLVIRVLWRVISPPPGPLPSYSPMTRLAARAGHLALYLLLF
                     AIGISGYLISTADGKPISVFGWFDVPATLADAGAQADFAGALHFWLAWSVVVLSVMHG
                     FMALKHHFIDKDDTLKRMLGKSSSDYGV"
     gene            2079..2654
                     /locus_tag="IT892_003096"
     CDS             2079..2654
                     /locus_tag="IT892_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HAP3136284.1"
                     /translation="MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLG
                     YSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKY
                     PQATFTSTSVKKDGDELDITGDLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGK
                     IKLKDFNIKTDLGPASQEVDLIISVEGVQQK"
     gene            complement(2696..3748)
                     /locus_tag="IT892_003097"
     CDS             complement(2696..3748)
                     /locus_tag="IT892_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAP3136285.1"
                     /translation="MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKATRDA
                     LYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDD
                     GKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYE
                     YEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGF
                     NKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDS
                     HTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNK
                     SRGRLNTTLCIPDPTE"
     gene            3973..4893
                     /locus_tag="IT892_003098"
     CDS             3973..4893
                     /locus_tag="IT892_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxL/LpxP family Kdo(2)-lipid IV(A)
                     lauroyl/palmitoleoyl acyltransferasee"
                     /protein_id="HAP3136286.1"
                     /translation="MTNLPKFSTALLHPRYWLTWLGIGVLWLVVQLPYPVIYRLGCGL
                     GKLALRFMKRRAKIVHRNLELCFPEMSEQERRKMVVKNFESVGMGLMETGMAWFWPDR
                     RIARWTEVIGMEHIRDVQAQKRGILLVGIHFLTLELGARQFGMQEPGIGVYRPNDNPL
                     IDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGEVVWYAPDHDYGPRSSVFVPLFAVEQ
                     AATTTGTWMLARMSGACLVPFVPRRKPDGKGYQLIMLPPECSPPLDDAETTAAWMNKV
                     VEKCIMMAPEQYMWLHRRFKTRPEGVPSRY"
     gene            5065..6291
                     /gene="mdtG"
                     /locus_tag="IT892_003099"
     CDS             5065..6291
                     /gene="mdtG"
                     /locus_tag="IT892_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtG"
                     /protein_id="HAP3136287.1"
                     /translation="MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQL
                     GVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMG
                     LAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPM
                     AGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNP
                     KLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAP
                     RLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQT
                     LLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAV
                     YSWNSLRRRRIPQVSN"
     gene            6374..6748
                     /locus_tag="IT892_003100"
     CDS             6374..6748
                     /locus_tag="IT892_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309456.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HAP3136288.1"
                     /translation="MTMYATLEEAIDAAREEFLADNPGIDAEDANVQQFNAQKYVLQD
                     GDIMWQVEFFADEGEEGECLPMLSGEAAQSVFDGDYDEIEIRQEWQEENTLHEWDEGE
                     FQLEPPLDTEEGRAAADEWDER"
     gene            complement(6749..6976)
                     /locus_tag="IT892_003101"
     CDS             complement(6749..6976)
                     /locus_tag="IT892_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HAP3136289.1"
                     /translation="MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDS
                     AWRYVTILDLPFSLVFDTLLLPIDIHHGPYE"
     gene            complement(7149..9692)
                     /gene="mdoH"
                     /locus_tag="IT892_003102"
     CDS             complement(7149..9692)
                     /gene="mdoH"
                     /locus_tag="IT892_003102"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis glucosyltransferase MdoH"
                     /protein_id="HAP3136290.1"
                     /translation="MNKTTEYIDAMPIAASEKAALPKTDIRAVHQALDAEHRTWARED
                     DSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMFPDPWRTNPVGRF
                     WDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTIL
                     PYQGWALINPMDMVGQDLWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQ
                     LLIGRDKYSISASTVGDEPLNPEHRTALIMPICNEDVNRVFAGLRATWESVKATGNAK
                     HFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDDFCRR
                     WGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFA
                     TRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDF
                     VEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHP
                     VHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPEL
                     AIALFASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLF
                     HTVFVVSAFLGWEVVWNSPQRDDDSTSWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLF
                     WLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVDTDRFLEMNRQ
                     RSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRR
                     LVLLSDPVTMARLHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ"
     gene            complement(9685..11220)
                     /gene="mdoG"
                     /locus_tag="IT892_003103"
     CDS             complement(9685..11220)
                     /gene="mdoG"
                     /locus_tag="IT892_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoG"
                     /protein_id="HAP3136291.1"
                     /translation="MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYETPK
                     SNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATA
                     VKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVI
                     GAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAY
                     KFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNG
                     LSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPS
                     AWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDED
                     KLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTS
                     IGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLP
                     ANE"
     gene            11614..12771
                     /gene="mdoC"
                     /locus_tag="IT892_003104"
     CDS             11614..12771
                     /gene="mdoC"
                     /locus_tag="IT892_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoC"
                     /protein_id="HAP3136292.1"
                     /translation="MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAES
                     SLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLL
                     TLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
                     RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTL
                     FYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETES
                     VITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHI
                     TSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR"
     gene            complement(12779..14260)
                     /locus_tag="IT892_003105"
     CDS             complement(12779..14260)
                     /locus_tag="IT892_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HAP3136293.1"
                     /translation="MMKKTPTSTKDSLPNKEMNDLPRLASAVLPLCSQHPGQCGLFPL
                     EKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLDDN
                     NTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVV
                     TLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDV
                     PEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTLPLIWAKTRLLSDDPAK
                     GEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTN
                     SLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKT
                     FSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLIDKRFIQSQYDAAWQLRLDR
                     WGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL"
     gene            complement(14202..14735)
                     /gene="ymdB"
                     /locus_tag="IT892_003106"
     CDS             complement(14202..14735)
                     /gene="ymdB"
                     /locus_tag="IT892_003106"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HAP3136294.1"
                     /translation="MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGP
                     ALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYL
                     NSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYD
                     EENAHLYERLLTQQGDE"
     gene            complement(14830..15141)
                     /locus_tag="IT892_003107"
     CDS             complement(14830..15141)
                     /locus_tag="IT892_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HAP3136295.1"
                     /translation="MFRPFLNSLMLGSLFFPFIAIAGSTVQGGVIHFYGQIVEPACDV
                     STQSSPVEMNCPQNGSIPGKTYSSKALMSGNVKNAQIASVKVQYLDKQKKLAVMNIEY
                     N"
     gene            complement(15262..15594)
                     /gene="csgC"
                     /locus_tag="IT892_003108"
     CDS             complement(15262..15594)
                     /gene="csgC"
                     /locus_tag="IT892_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli assembly protein CsgC"
                     /protein_id="HAP3136296.1"
                     /translation="MNTLLLLAALSSQITFNTTQQGDVYTIIPEVTLTQSCLCRVQIL
                     SLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPDDRVKIVVTVSDGQSLHLSQQ
                     WPPSSEKS"
     gene            complement(15653..16108)
                     /locus_tag="IT892_003109"
     CDS             complement(15653..16108)
                     /locus_tag="IT892_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major curlin subunit CsgA"
                     /protein_id="HAP3136297.1"
                     /translation="MKLLKVAAIAAIVFSGSALAGVVPQYGGGGNHGGGGNNSGPNSE
                     LNIYQYGGGNSALALQTDARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSAT
                     LDQWNGKNSEMTVKQFGGGNGAAVDQTASNSSVNVTQVGFGNNATAHQY"
     gene            complement(16149..16604)
                     /gene="csgB"
                     /locus_tag="IT892_003110"
     CDS             complement(16149..16604)
                     /gene="csgB"
                     /locus_tag="IT892_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin minor subunit CsgB"
                     /protein_id="HAP3136298.1"
                     /translation="MKNKLLFMMLTILGAPGIAAAAGYDLANSEYNFAVNELSKSSFN
                     QAAIIGQAGTNNSAQLRQGGSKLLAVVAQEGSSNRAKIDQTGDYNLAYIDQAGSANDA
                     SISQGAYGNTAMIIQKGSGNKANITQYGTQKTAIVVQRQSQMAIRVTQR"
     gene            17359..18009
                     /gene="csgD"
                     /locus_tag="IT892_003111"
     CDS             17359..18009
                     /gene="csgD"
                     /locus_tag="IT892_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CsgD"
                     /protein_id="HAP3136299.1"
                     /translation="MFNEVHSIHGHTLLLITKSSLQATALLQHLKQSLAITGKLHNIQ
                     RSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWP
                     HINGVFYSMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
                     KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR"
     gene            18014..18403
                     /gene="csgE"
                     /locus_tag="IT892_003112"
     CDS             18014..18403
                     /gene="csgE"
                     /locus_tag="IT892_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgE"
                     /protein_id="HAP3136300.1"
                     /translation="MKRYLRWIVAAEFLFAAGNLHAVEVEVPGLLTDHTVSSIGHDFY
                     RAFSDKWESDYTGNLTINERPSARWGSWITITVNQDVIFQTFLFPLKRDFEKTVVFAL
                     IQTEEALNRRQINQALLSTGDLAHDEF"
     gene            18428..18844
                     /gene="csgF"
                     /locus_tag="IT892_003113"
     CDS             18428..18844
                     /gene="csgF"
                     /locus_tag="IT892_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgF"
                     /protein_id="HAP3136301.1"
                     /translation="MRVKHAVVLLMLISPLSWAGTMTFQFRNPNFGGNPNNGAFLLNS
                     AQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIV
                     DIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF"
     gene            18871..19704
                     /gene="csgG"
                     /locus_tag="IT892_003114"
     CDS             18871..19704
                     /gene="csgG"
                     /locus_tag="IT892_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgG"
                     /protein_id="HAP3136302.1"
                     /translation="MQRLFLLVAVMLLSGCLTAPPKEAARPTLMPRAQSYKDLTHLPA
                     PTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIPLERQGLQ
                     NLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFG
                     IGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGE
                     VGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQNKAERQNDILVKYRHMSVPPE
                     S"
     gene            complement(19768..20259)
                     /locus_tag="IT892_003115"
     CDS             complement(19768..20259)
                     /locus_tag="IT892_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415554.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HAP3136303.1"
                     /translation="MNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQ
                     GGLKGLAISAATLLSGVVWAMVIIYGSALAPHLEILGYVITGIVAFLMCIQAKQLLLS
                     FVPGTFIGACATFAGQGDWKLVLPSLALGLIFGYAMKNSGLWLAARSAKTAHREQEIK
                     NKA"
     gene            complement(20361..20915)
                     /locus_tag="IT892_003116"
     CDS             complement(20361..20915)
                     /locus_tag="IT892_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HAP3136304.1"
                     /translation="MNEFSILCRVLGSLYYRQPQDPLLVPLFTLIREGKLAANWPLEQ
                     DELLTRLQKSCDMTQVSADYNALFIGDECAVPPYRSAWVEGATEAEVRAFLSERGMPL
                     ADTPADHIGTLLLAASWLEDQSTEDESEALETLFSEYLLPWCGAFLGKVEAHATTPFW
                     RTMAPLTRDAISAMWDELEEDSEE"
     gene            complement(20939..21676)
                     /locus_tag="IT892_003117"
     CDS             complement(20939..21676)
                     /locus_tag="IT892_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HAP3136305.1"
                     /translation="MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDM
                     EDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHE
                     PVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNS
                     SFLHSRKGSEDNCREVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPER
                     ILNVSPRRLLNFLESRGMAPIAEFADL"
     gene            complement(21731..22669)
                     /gene="ghrA"
                     /locus_tag="IT892_003118"
     CDS             complement(21731..22669)
                     /gene="ghrA"
                     /locus_tag="IT892_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415551.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /protein_id="HAP3136306.1"
                     /translation="MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALV
                     WHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLNPSVPLFRLEDTGMGEQMQEY
                     AVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRF
                     PLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPD
                     GAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHV
                     AAITRPAEAVEYISRTIAQLEKGERVCGQVDRARGY"
BASE COUNT         5869 a         5785 c         5393 g         5921 t
ORIGIN      
        1 ttccgtaggc gctgccgccg ggtattatgc aacccgcgcc ggtttaaacg tgctaatgac
       61 cgacgcccat atgccaccgc atcaacacgg cagccaccac ggcgatacgc gattaattcg
      121 ccatgcttat ggtgaaggcg aaaagtatgt cccgctggtc ctccgcgcgc aaacgctgtg
      181 ggatgaactc tcccgccaca acgaagaaga tcccattttt gtacgctctg gcgtcattaa
      241 ccttggcccg gctgattcca catttctcgc caacgtcgcc cacagcgccg aacaatggca
      301 actcaacgtt gaaaagctcg atgcgcaagg gattatggcc cgctggccgg aaatacgcgt
      361 cccggacaac tacatcggct tatttgaaac tgattccggt tttttgcgca gcgaactggc
      421 gattaaaacc tggatccaac tggcgaagga agcgggctgt gcgcaactgt tcaactgccc
      481 ggtcaccgca attcgtcatg acgatgatgg cgtaactatt gaaacggctg acggtgagta
      541 tcaggcgaaa aaagcgattg tctgcgcggg aacatgggta aaagacctgc tcccggagct
      601 gcctgtccag cccgtacgca aagtatttgc ctggtatcag gccgatggcc gctatagcgt
      661 gaagaataaa ttcccggcgt ttaccggtga actgcccaat ggcgatcaat attatggttt
      721 tccggcagaa aacgacgcgt tgaagattgg caaacataac ggaggccagg ttatccattc
      781 agcggatgaa cgtgttccgt ttgcggaagt ggccagtgat gggtcaaaag ccttcccgtt
      841 cttgcgcaat gtattgccgg gtatcggttg ctgcctgtac ggcgctgcct gcacctatga
      901 taattcgcct gacgaagatt ttattatcga taccctaccc ggccacgata atacactgct
      961 cattaccggc ctgagtgggc acggttttaa atttgcgtca gttttagggg aaatagctgc
     1021 cgattttgcg caagacaaaa aaagcgattt tgatttgacg ccattcaggc tttcccgctt
     1081 ccaataatca tcattacggc ctccagaatg aggccgtttt tacaggagta tttaatgcgt
     1141 cggctgttgc actatctcat caataatatt cgcgagcatc tgatgcttta tctttttctc
     1201 tggggattgt tggcaattat ggatctgatc tatgtgtttt atttttagtt ttccgcactg
     1261 acataaactg acaaatattt aatctccctt tcatttagcg tgaaaaattg aatgagatta
     1321 ttcctgcttc tacagcactc accagacatc tctgatgctg aacccactaa acttatgaag
     1381 attctttcat tattaattca aaattattga aataaaaata aatatcattc aatttgttat
     1441 ttttgtgttg caattcattc tccgacacgc cattttcttt ctctcgcaaa ttcgttttgg
     1501 atgcacttat gtcattcaca aatacccctg aacgctatgg tgttatatct gcggccttcc
     1561 attggctaag cgcaattatt gtctacggca tgtttgcttt aggtctgtgg atggtcacgc
     1621 tcagttatta cgatggctgg tatcacaaag cacccgaact gcataaaagc atcggtattt
     1681 tgttaatgat ggggctggtt attcgcgttc tgtggcgtgt catatctcca ccgccgggtc
     1741 cgctgccgag ttattcgccc atgactcgtc ttgccgcaag agctggacat ctcgcattgt
     1801 acctattgct tttcgccatc ggcatcagcg gctatctgat ctcaactgcc gatggtaaac
     1861 cgatcagcgt ttttggctgg tttgacgtcc ccgcgaccct tgccgacgct ggcgcacagg
     1921 cagactttgc cggtgccctg catttttggc tcgcgtggag cgtcgtagta ctgtccgtta
     1981 tgcacggatt tatggccctg aagcatcatt tcatcgataa agacgacact ctgaagcgca
     2041 tgctgggaaa gtcgtcatct gactatggag tataaaaaat gaaaaaaagc ctgcttggtt
     2101 taaccttcgc gtccctgatg ttctctgccg gttcagcggt tgccgccgat tacaaaattg
     2161 acaaagaagg tcagcacgcc tttgttaatt tccgcatcca gcaccttggc tatagctggt
     2221 tatacggcac ctttaaagat ttcgacggta cttttacctt tgacgaaaaa aatccggctg
     2281 ccgataaagt gaatgtgaca attaacacca ccagcgtcga tactaatcac gccgaacgcg
     2341 ataaacatct tcgcagtgca gatttcctca ataccgcaaa atatccacag gcaacattca
     2401 cctccaccag cgtgaagaaa gacggtgacg aactggatat taccggcgat ctgacgctga
     2461 atggcgtaac caaacccgtc acgctggaag cgaaattaat tggtcagggc gacgacccat
     2521 ggggtggtaa acgtgcaggc ttcgaggccg aaggcaaaat taagctcaag gacttcaata
     2581 tcaagacaga tttaggtcca gcttctcagg aagtggatct gattatttca gtggaaggcg
     2641 tacagcagaa gtaagcgtga aatgttgccg gatggcacgc atccggcaat gatatttatt
     2701 ctgttggatc aggaatgcac agtgttgtat tcagacgtcc acgagactta ttaaagatct
     2761 tattgccatt ttcacgtcct gcccgacggc gtcgctgttc ttctggcggt aacgcgcttt
     2821 cttcgcagca aatctcacta caacaacctt tgtatttttc cgcgcatact ggacactgaa
     2881 taaacagcag gtggcagcca tcatttttac agttggtatg gctgtcgcac ggcgcgccgc
     2941 actggtggca atgcgcgata atctcatccg atatacgttc gcccatccgc tcgtcaaaaa
     3001 caaaattttt gccaataaaa cgcaccggca agccctgctc gcgcgcctta cgggcgtatt
     3061 caataattcc gccctcgata tgccagactt tgttgaatcc gttatgtttc atccaggcac
     3121 tggccttttc acaacgaatg ccgccggtgc agtacatgac gattttttta tctttatgtg
     3181 cctgcatcat ctcgactgct tttggcagct gctcacggaa ggtatctgcc ggaatttcga
     3241 gcgcgttttc aaagtgcccc acttcatact catagtggtt acgcatgtcg ataaatagtg
     3301 catcgggatc gtcaagcatg gcgttcactt ccgccgcttg cagatactca ccaacattgc
     3361 tggcatcaaa gtgaggatcg tcaataccgt cggcaacaat gcgatcgcgt accttcatgc
     3421 gcagtaccca gaaggatttc ccgtcatcat ccaacgcgat attcaggcgt aaaccctcta
     3481 aagccgggtc gaaggcatag agctgcgcgc gaaatgtttc aacattgctc gcaggtacgc
     3541 tgatttgcgc gttaatgccc tcatgcgcca gatacactcg cccaaaaaca ttcagcgcgg
     3601 taaacagctg atataaagcg tcacgggtcg ccttaggatc ggcgatgtgg aaatacttgt
     3661 aaaacgaaat ggtggttcgc ggttcgctct cagccaacat tttggctttt agcgcgtcgt
     3721 tggaaatgcg gttgtgtaac actggcatgg tgtacggttc ctgcgagatg ggaaagtaaa
     3781 aatccgcggc atgatatagc aattatcgat aattaacatc cacacatttt acgctacatt
     3841 tgcgcattaa aaattatttg ttatttacaa gcgcggcaat ttcgcccagt cttcagccac
     3901 aaattttggt tgcgggcgaa aaaatgcgac aatacataca attgcccgaa taggttgaaa
     3961 aacaggattg atatgacgaa tctacccaag ttctccaccg cactgcttca tccgcgttat
     4021 tggttaacct ggttgggtat tggcgtactt tggttagtcg tgcaattgcc ctacccggtt
     4081 atctaccgcc tcggttgtgg attaggaaaa ctggcgttac gttttatgaa acgacgcgca
     4141 aaaattgtgc atcgcaacct ggaactgtgc ttcccggaaa tgagcgaaca agaacgccgt
     4201 aaaatggtgg tgaagaattt cgaatccgtt ggcatgggcc tgatggaaac cggcatggcg
     4261 tggttctggc cggaccgccg aatcgcccgc tggacggaag tgatcggcat ggaacacatt
     4321 cgtgacgtgc aggcgcaaaa acgcggcatc ctgttagttg gcatccattt tctgacactg
     4381 gagctgggtg cgcggcagtt tggtatgcag gaaccgggta ttggcgttta tcgcccgaac
     4441 gataatccac tgattgactg gctacaaacc tggggccgtt tgcgctcaaa taaatcgatg
     4501 ctcgaccgca aagatttaaa aggcatgatt aaagccctga aaaaaggcga agtggtctgg
     4561 tacgcaccgg atcatgatta cggcccgcgc tcaagcgttt tcgtcccgtt gtttgccgtt
     4621 gagcaggctg cgaccacgac cggaacctgg atgctggcac ggatgtccgg cgcatgtctg
     4681 gtgcccttcg ttccacgccg taagccagat ggcaaagggt atcaattgat tatgctgccg
     4741 ccagagtgtt ctccgccact ggatgatgcc gaaactaccg ccgcgtggat gaacaaagtg
     4801 gtcgaaaaat gcatcatgat ggcaccagag cagtatatgt ggttacaccg tcgctttaaa
     4861 acacgcccgg aaggcgttcc ttcacgctat taaatctccc atgccggatg cttcagaatg
     4921 gcatccggca ttaccacagc aaatccccct gatttagcga taaaagctct ctggattgcg
     4981 ccccctggaa gtcgggcgca taattagtgt gcttatcttt tcttcttatg ttcaccgcgc
     5041 ctggcgcacc aacagcggat tgctatgtca ccctgtgaaa atgacacccc tataaactgg
     5101 aaacgaaacc tgatcgtcgc ctggctaggc tgttttctta ccggtgccgc cttcagtctg
     5161 gtaatgccct tcttacccct ctacgttgag cagcttggcg ttaccggtca ctccgccctg
     5221 aatatgtggt ccggtattgt cttcagcatt acatttttat tttcggccat cgcctcaccg
     5281 ttttggggtg gactcgccga ccgtaaaggc cgaaaactca tgctattacg ctctgccctc
     5341 ggcatgggca tcgtgatggt gttgatgggg ctggcacaaa atatctggca gtttttgatc
     5401 ctgcgggcgc ttcttgggtt acttggcgga tttgtcccca acgctaatgc tcttatcgcc
     5461 acacaagtac cgcgtaataa aagcggctgg gcgctgggta cgctctccac aggcggcgtt
     5521 agtggtgcgt tgctcggccc aatggctggc ggcctgctcg ccgatagcta cggcttacgt
     5581 ccggtattct ttattaccgc cagtgtgctc atactctgct ttttcgtcac cctgttttgc
     5641 atcagagaaa aattccagcc ggtcagcaaa aaagagatgc tgcacatgcg ggaagtggtg
     5701 acatcactta aaaacccgaa actggtactc agcctgtttg tcactacgtt aatcatccag
     5761 gtggcgacgg gctcaattgc ccccattctg acgctgtatg tccgcgaact ggcgggtaac
     5821 gtcagtaacg tcgcctttat cagtggcatg atcgcctcgg tgccaggcgt ggcggctctg
     5881 ctaagtgcac cacgactcgg caaacttggc gatcgaatcg gacccgaaaa gatcctgatt
     5941 acagcgctga tcttttctgt actgctgttg atcccaatgt cttacgttca gacgccattg
     6001 caacttggga ttttacgttt tttgctcggt gccgccgatg gtgcactact ccccgccgta
     6061 cagacactgt tggtttacaa ctcgagcaac cagatcgccg ggcgtatctt cagctataac
     6121 caatcgtttc gtgatattgg caacgttacc ggaccattga tgggagcagc gatttcagcg
     6181 aactacggtt tcagagcggt atttctcgtc accgctggcg tagtgttatt caacgcagtc
     6241 tattcatgga acagtctacg tcgtcgtcga ataccccagg tatcgaactg atttttcgcc
     6301 tttcatactt gcaaaagcgg agaatcagct atccttttcc ctgaaacctc atcaactcaa
     6361 agggagaatc gtgatgacca tgtacgcaac gcttgaagaa gccattgacg ctgcacgcga
     6421 agaatttctt gcagacaacc ccggcatcga cgccgaagat gcgaatgtgc aacagttcaa
     6481 tgcccaaaaa tacgttttgc aggacggcga catcatgtgg caagttgagt tttttgccga
     6541 cgaaggggaa gaaggtgaat gtttacctat gcttagcggt gaagccgcgc aaagtgtttt
     6601 tgatggcgac tatgatgaga tagagatacg ccaggagtgg caggaagaga atacattaca
     6661 tgaatgggac gagggggaat ttcagcttga gccaccgctg gataccgagg aaggacgcgc
     6721 agcagctgat gagtgggatg aacgttaatc actcatacgg gccatgatga atgtcgatcg
     6781 gcagcagtaa agtatcaaaa accagagaga atggcagatc aaggatcgtg acataacgcc
     6841 aggcggagtc acgcacatcc cattgcacac cgggataata ttggttgcca tgcccctgcc
     6901 ccggtatagt gcgactaata atgctgccac agccactcag caaggtcacc atgatgctca
     6961 ccacaattaa acgcatttga tacctctttc gtaaaaaaat accggcataa cgccggtatt
     7021 tttattggct cgttgttttt gccggatgcg gcgtgaacgc cttatccgac ccacaaagtc
     7081 ttgcaaaatc aataaattgc aggaacgatg taggcctgat aagcgtagcg catcaggcaa
     7141 ctacgttttt attgcgaagc cgcatccggt ttacgcaatg ccagtggatt gagctttatc
     7201 ccttcgtaat aactcaccca tgaagaatat ctctccgggg aattccagac acggaaatgc
     7261 agacgggcca tcgtcaccgg atcgcttagc agcaccaggc gacgatcgcg attcagcttc
     7321 tctggcgtct cgttcagcgc ctgttcaacg tggcggtcac gggcgatttc cagcacctta
     7381 ctggcgcggt gacgcgcggt cgccattgcg gttgccagag cgttaaatga cgggttaaac
     7441 actgcgtgca taaagccatc atcaagggag cgttgacgat tcatctcaag gaaccgatcg
     7501 gtatcaacca gcacctgcgg cggcgaatac tcttccggga tcaggaacag tttccagcgt
     7561 ttggtgcgca gaccaacggt ggcacggctg gaaatcaccg aaacaaacgg tgacaggatc
     7621 aacgagaaga caatcggtgc cagccagaac aggaaacgca gatccagcca cgccatccca
     7681 acagcccaca ctaaccctaa cagcagctgt gagccgtggc gtttgaacgc ttcaccccag
     7741 gaagtggagt catcatcacg ctgcggtgaa ttccacacca cttcccagcc aaggaacgcg
     7801 ctgacaacga agaccgtatg gaacagcatg cgtaccggag ccagcagcac ggaaaaaagc
     7861 acttccagca gcaacgataa tgtaacgcgc cagaagccgc cgtattcttt cgttcctttg
     7921 caccagataa gcaaaatgct caataacttc ggcaggaaca acagcaccat ggtcgaagca
     7981 aaaagtgcaa tcgccagctc aggacgccac tgcggccaca ctgggaacaa ctgccgtggt
     8041 tgcaggaagt attgcggttc ggtcaacgca tgcactacct gcaatgcagt agagagcgcg
     8101 aggaacataa accacagcgg agcggagaga taagacatca cgcccgtcag gaacaccgca
     8161 cggtgaaccg ggtgcatacc cttcaccagg aacagacgga agttcatcag gttaccgtgg
     8221 caccatcggc ggtcacgttt tagctcatca agcaagttag gcggcaattc ttcataagaa
     8281 cccgggagat cgtaagcaat ccagaccccc caacctgcac ggcgcatcaa cgccgcttcc
     8341 acgaagtcat gtgacaggat tgaaccggca aaggaacctt cgcccggcag cggagccagt
     8401 gcgcagtgct cgataaacgg tttcacgcgg ataatcgcgt tatgtcccca gtagtgcgac
     8461 tcgccaagtt gccagaagtg caaaccggct gtaaacagtg gcccatacac gcgggtcgcg
     8521 aactgctgac agcgcgcata cagcgtatcc ataccggacg ctttcggcga cgactgaatg
     8581 atcccggcgt tcgggttggc ttccatcagg cgcaccagcc cgcacaaaca atcaccggtc
     8641 attaccgagt cagcatccag caccaccatg tagctgtact ggctgcccca gcgacggcag
     8701 aagtcatcga tattaccgct tttacgcttc acgcggcgac ggcggcggcg atagaaaatc
     8761 tgaccttcgc caccgacttc agcgataagc tccatccagg ctttttgctc tgcgacgcag
     8821 atatccgggt tataactgtc actaagaatg tagacatcaa agtgtttggc attcccggtg
     8881 gcttttactg attcccacgt tgcacgcagg ccagcaaaaa cacggttcac gtcttcgtta
     8941 cagataggca tgatcaacgc cgtgcgatgc tccgggttta atggttcatc gccaactgtt
     9001 gacgcagata tactgtattt atcgcgacca ataagcagtt gcaggaagcc cattaacgcc
     9061 gtccagaatc cggcggacac ccaacagaac agtaccgcaa agaggatcag gataccggtt
     9121 tgcagcatat aaggcagaag ctgcataaag gaaacccaca aatcctgacc aaccatatcc
     9181 ataggattaa tcagcgccca accctgataa ggaagaatgg tcttcatata ccaggtcgcg
     9241 acgacagttt gcgcgagcgt caggatcaac agaatgtaac ggcggatggt accgacggta
     9301 cgccactttt gctcgctctc ctgctcttct ttggtcaaac gagccagata gcgcggcgtg
     9361 acatcgcgtc cacgcaggcg atcccagaaa cggcctaccg ggttggtacg ccacgggtcg
     9421 ggaaacatcg aggagcgttt tgcttctggc atcgccttca gctgatcgcg cccttcgtcg
     9481 tctttaatta actgtccatc agcaagtgaa tctggccagg cttgttccag acgcgccttt
     9541 accgagcctt gcggggaatc atcctcccgc gcccaggtgc ggtgttcggc atccagcgcc
     9601 tgatgaacgg cgcggatatc agtcttcggc aatgccgctt tctcgcttgc ggcgatgggc
     9661 attgcgtcaa tgtactcagt tgtcttattc attggcaggt aactggtagc tccaggtttc
     9721 actcaacgtc tgatcggcat tcaccagcgc agcacgcatt tcagtggttt tcttggcatc
     9781 tttcactttc acacgcatca ccagacgcca gcctttggta accgggttat agcgcaccgt
     9841 gctttcaact atctcaccat tatcaccaat gctggtttgc gctgtgaccg gggtatcctc
     9901 tggcagtttt ttcatctctg cgccggtaaa atcgaccaca aaggcgatag taccgtcagg
     9961 ctggcgaatc aggttcgact gcttcacatc ccccgttgaa cgacgcgttt gttgcaccca
    10021 tgcgttatct ggcgcatgca gtttgtcttc atcacggctg aaggtgatgg tgtatttaaa
    10081 gttcatctct ttacccggct ccggcagctg atccggcgtc cagtaagcga cgatgttatc
    10141 gttggtttca tcgttggttg gaatttccac cagctcaacg ctgcctttac cccactcccc
    10201 tttcggagtc acccatgcgc ttggacggag atcgtaacga tcatcgagat cttcaaagcg
    10261 ggagaaatca cgaccgcgct gcaacagacc aaagccttgc gggttttcca tggagaagct
    10321 gctgaccgct aaatgtttcg ggttattcaa cggacgccag atccattcgc cattaccggc
    10381 atggatagag agaccgttag agtcgtgcaa ctccggacga tagttatttg caggcgacgg
    10441 ttggttcggc ccaaacagga acatactggt taacggtgca acccccagtt tgccgacttt
    10501 atcgcgcaga tagattttcg actgcacatc cacaaccgtg tcacgccctg gcataaccac
    10561 gaatttgtaa gcacctgtcg cacgcggcga gtcaagcaat gcatagatgg ttaaacgttt
    10621 atcagtcggt tttggacgct cgatccagaa ctctttgaag cgcggaaatt cttcacccga
    10681 tggcaaggcg gtatcaattg ccaggccgcg ggcagaaagg ccataaacct gacctgcacc
    10741 aatcacgcgg aaatagctgg ccccgagcat gctgacgatt tcatcgtttt tatctttgct
    10801 gttgatcggg taaagcactt taaaaccggc aaagccaagg tcttttaccg tatctttgtc
    10861 atgctgaaca tcgccgaaag tgaaataatc cgggctgtat ttgattcgtt tgactgcggt
    10921 ggcagtcact tcatttattt tgaccggggt atcgaagtac ataccctgat ggtagaactc
    10981 gagtttgaat ggggtcttca gattgttcca gtacgctttg tcatgattaa actggatctg
    11041 ctgatagtcc gcgtatttca tatcgcggaa aacggagggc aagttgcttt tgggcgtctc
    11101 gtagcctttc ccggctaaag attgagcttg ctttgcgaca tcatcaatac tgaaagccca
    11161 gcttgaagat gtatacaggg ttaacattac tgcagcactc aaccaacgca ttttcatcat
    11221 ttgtagttta tgtttcataa ttagtaagca cttccccctt tgtgtgctta tatcgatccg
    11281 atctatttta atggataacc agccattccg acaacagaat cccggtatcg ttcagcacgc
    11341 tggctcatgg attaagcacc tgattgcaac cgttttcact ttccgtgctt ctcctaaaga
    11401 cagaagcatc gacttcgtgt agggtttgcc agcaaattta tttatcaacc gtcttacaga
    11461 cgcttccatt ctggttagtg gtagcgatga tgctatgcat aaaaaccttg aagcctgcgc
    11521 ctggcgcggt caggtcggtg tcactatggc aacaagccta aaggcataac ccgacaggga
    11581 taagacgaaa aatccgagat tagttaacca tatatgaacc cagtacccgc gcaacgtgaa
    11641 tatttcctcg actccatccg cgcctggctg atgttgttag ggataccttt tcatatttct
    11701 ttaatctatt cgagccatac atggcatgtg aatagcgccg aatcatcatt gtggctgacc
    11761 ctttttaatg acttcatcca ctcgttccgc atgcaggtat ttttcgttat atccggctac
    11821 ttttcctaca tgcttttttt acgctatccc ttgaaaaaat ggtggaaagt acgtgtcgaa
    11881 cgtgtaggta tcccgatgtt aacagccatc cccctactga cattaccgca atttattatg
    11941 ctgcaatatg tcaaaggaaa agcggaaagt tggcctgggc tgtcattgta tgacaaatat
    12001 aatacgttgg cctgggaatt aatatcacac ctgtggtttt tactggtgtt agtggtcatg
    12061 acgacgctgt gcgtatggat atttaagcgc atcagaaata atttagaaaa ttctgataaa
    12121 acgaataaaa aattctcgat ggtaaaacta tcggtgattt ttttatgcct cggcatcggt
    12181 tatgcggtaa taagaagaac gatttttatt gtgtatccgc ccattctgag taatggcatg
    12241 ttcaatttta ttgtcatgca aacgctgttt tatttgccgt tctttatcct cggcgcactg
    12301 gctttcattt tccctcatct taaagccttg tttaccacgc cgtctcgtgg ctgtaccctt
    12361 gcagcagcat tggcgtttgt cgcttattta ctcaaccagc gctatggcag tggcgatgcc
    12421 tggatgtacg aaaccgagtc ggtgatcacc atggtcctcg gtctgtggat ggtgaatgtg
    12481 gtcttctcct ttggccaccg tttgcttaac ttccagtcag cgcgggtgac ttattttgtt
    12541 aacgcatcgc tgtttatcta tctggttcac cacccgttaa cgctgttttt cggcgcatac
    12601 attacaccgc acatcacctc caactggctt ggttttctct gtggcctgat atttgtagta
    12661 gggattgcga taattctgta tgaaattcat ttgcgcatcc cgttactgaa gtttttgttc
    12721 tctggtaaac cggttgttaa gcgtgagaac gataaagcac cagcccgtta agccacattt
    12781 acaataacca ttccacgggc aatatcgacg ccagtctgac cataacccgc ttccagaaac
    12841 tggtggcggg ttcttttttg agaataatct ctttctttgc atgacgatca acccagttga
    12901 tccgtcccca cctgtccaga cggagctgcc aggccgcatc atactggctc tgaataaagc
    12961 gtttatcaat taactgtgcc agcgtttcgc tctctatcac gaagcccatt tcagtattga
    13021 gcaatgttga acgcggatcg aaattgaaag agccgataaa caccgtttta ccatcgatgc
    13081 taaaggtttt agcatgcagg ctggctccgg aattaccggt tatgccgcga tcgtgtaacg
    13141 tactactttg ttcacgcgtc ggcttgagtt catataattc cacgccatag cggagcaatt
    13201 ttttgcgcca gcgcgcgtat ccggcatgga cgacagcaac atcgttagcg gcaagagaat
    13261 tggttaggat cgcaatcttt accccttttc tcaccatccg taagagttgc gccacacctg
    13321 cgcgtgtcgg tacaaaatag gaagagataa tatcgatgcg ttcactgggt gagcccatga
    13381 tatcgaacag gcgctgcggt aacagtgaat gccgttttgc cttgccctcc cctttcgccg
    13441 gatcatcact taataaacgt gtcttcgccc agataagcgg caatgttcca tcaaccagat
    13501 gatttataaa tggactggat tccattttgc gtaaataacg atgcgtcatg gcatcgttat
    13561 gccaggaggc gggtaactcg atgcgatccg ccatttcacc ctccgggaca tccagcacct
    13621 gctgtaaggg tgaaaccgat ttgcaatacc agtagcgggc gaaatcatcg gcaacgtctt
    13681 ctaccacggg tcctattgcc atgacatcta aatccgaaaa aagtggctcc tcccctgctc
    13741 caaaataggc atcaccaata tttcgtcctc ccaccagggt caccacgcca tcgacagtga
    13801 aacttttatt gtgcatacgg cgattaagac gggaaaagtc ggtgatataa ccaagcggac
    13861 gcagcaagcg aaacgagaaa ggattaaaaa gccggacttc aatgcgtgga tgactgtcaa
    13921 gcaagcgtaa aatgtcgtca agtccgggcg tattgttgtc gtccagcaac aaacggacgc
    13981 gaacgccacg ctttgctgcg gctaacaggg cggaaaacag taaccgaccc gacatatcgt
    14041 cctgccagat gtaatactga acatcgagcg tatgctctgc catttcggcc agacgatacc
    14101 gggcggcaaa cgcatccaga cttttctcca gaggaaaaag gccacactga ccgggatgtt
    14161 gcgaacacag tggcagcacc gcgctcgcca gccggggcaa atcattcatc tccttgttgg
    14221 gtaaggagtc tttcgtagag gtgggcgttt tcttcatcat aacagacaaa gtatacctgt
    14281 tcgggtaaag cgtgacgggt aataaattct gaaacggttt ttactgcgat ttcagccgct
    14341 gccgcacgag ggtaaccata aaccccagta ctgattgcag gaaaagccac tgacgtatag
    14401 ctgtttgccg ccaccagtcg taggctattg agataggcat cctgcaaaag ctggtcttcg
    14461 ttttgttcac caccacgcca gactggcccg acggtgtgca ctacggcttt agcgggaaga
    14521 tcgcctgcaa gcgtaataac ggcatgcccc gtagggcaat cgccctgctg ttgcctgact
    14581 tttaaacaag catccagcag ggccggaccc gctgcgcgat gaatggcccc atcgacgccg
    14641 ccgcctccca ttaatgacgg attagccgca ttcacaatca catcaacggc cagtttggta
    14701 atatcaccct gcacaacatg aatacgcgtt ttcataacgc ctccttacac cttcttgttt
    14761 cttaagtgta cagcaggctt tttggttaaa tcgcattttt ctgctcagca acgtgagttg
    14821 ttcagaaact tagttatatt cgatgttcat tacagccagc tttttctgtt tatcaagata
    14881 ctgcactttt actgaggcta tttgcgcgtt tttgacattg ccgctcatta acgctttgct
    14941 ggagtaggtt ttgcccggaa tagaaccatt ctgtgggcag ttcatttcta cgggtgatga
    15001 ctgggtgctg acgtcacatg ccggttccac aatttggcca taaaaatgga tcacgccccc
    15061 ttgcacggtg cttccagcaa tggcaataaa aggaaaaaac aaactgccga gcataagaga
    15121 gtttaaaaaa ggtctgaaca tttattctat ttcctcaatg attagtcatc cttgagggtt
    15181 gtgttatcca tactttcagg ttggctgatt cgcagcagac cattctctcc agattcatct
    15241 tatgctcgat atttcaacaa attaagactt ttctgaagag ggcggccatt gttgtgataa
    15301 atgaagtgac tgtccatcag aaacagtaac aactattttc acccgatcgt ccggggaaat
    15361 atttaaactc aacttcgtca aagcaatggg ttgattagca ggcaatgaaa gggtcttttc
    15421 ttgcttcgtc tgactttgcc ctgaactgcc ttcgcgcagg gataatattt gtactctgca
    15481 cagacaagat tgagtaagag tgacttcagg aataatggta tacacatccc cttgctgggt
    15541 cgtattaaag gttatctgac tggaaagtgc cgcaaggagt aataacgtat tcatattctt
    15601 ctcccgaaaa aaaacagggc ttgcgccctg tttctgtaat acaaatgatg tattagtact
    15661 gatgagcggt cgcgttgtta ccaaagccaa cctgagtcac gttgacggag gagttagatg
    15721 cagtctggtc aactgcagca ccgttgccac caccgaactg tttaaccgtc atttcagaat
    15781 ttttgccgtt ccactgatca agagtagcgc tgttaccgaa gccacgttgg gtcagatcga
    15841 ttgagctgtc atctgagccc tgaccaacat ctgcaccatt accgccgcca tgctgggtaa
    15901 tagtcaagtc agagttacgg gcatcagttt gcagagcaag tgcagagtta ccgccaccgt
    15961 actggtaaat gttcagctca gaatttgggc cgctattatt accgccacca ccgtggttac
    16021 cgccgccgcc gtactgagga acaacacctg ccagagcgct accggagaat acgattgctg
    16081 caattgctgc tacttttaaa agtttcatgt aaaaccccca tcggattgat ttaaaagtcg
    16141 aatggaaatt aacgttgtgt cacgcgaata gccatttgcg actgtctctg cactacaatt
    16201 gccgtttttt gagtaccata ctgtgtaata tttgctttat taccagaacc tttctggata
    16261 atcatcgcag tattaccata agcgccttgc gaaatactgg catcgttggc actgcccgcc
    16321 tgatcaatat atgcaaggtt ataatctcct gtctggtcaa tctttgcccg gttgctacta
    16381 ccttcttgcg caacaaccgc caaaagtttt gagcctccct gccgtaactg agcactatta
    16441 ttagtcccag cttgaccaat tatggctgcc tgattaaatg aagacttact caattcattt
    16501 accgcgaagt tatattctga attagctaaa tcataacctg ctgcggctgc aatcccaggc
    16561 gcacccagta ttgttaacat cataaataac aatttgtttt tcatgttgtc accctggacc
    16621 tggtcgtaca tttaagaaat taaatcattt caacttggtt gttaacgcaa cctgtatttt
    16681 gttaacgctg cgttacgatg gaaagtatgt ctgcggaaat atttttaata actcacccgc
    16741 gcgttgtatt tttctttttt agttcatacc aaagtattaa aacccacgta aatacgctgt
    16801 tatctacgca aaaaaatatt ttgttttctt ttaaatctcc gttttccgct atcaaaaagc
    16861 accagacagt cattcttctt gcccgtcgct gattgctgcg atatgtcttg cgcacaagcc
    16921 gtgacaaacc tcgtcttttt gcagtaaaaa attgtccacg gaggtgtgga gaaaaaacaa
    16981 gaacgtttta catgacgaaa ggactacacc gaaatatttt ttatatgcat tattagtaag
    17041 ttatcaccat ttgtatgatt ttttaaaatt gtgcaataaa aaccaaatgt acaacttttc
    17101 tatcatttct aaacttaata aaaccttaag gttaacattt taatataacg agttacattt
    17161 agttacatgt ttaacacttg atttaagatt tgtaatggct agattgaaat cagatgtaat
    17221 ccattagttt tatattttac ccatttaggg ctgatttatt actacacaca gcagtgcaac
    17281 atctgtcagt acttctggtg cttctatttt agaggcagct gtcaggtgtg cgatcaataa
    17341 aaaaagcggg gtttcatcat gtttaatgaa gtccatagta ttcatggtca tacattattg
    17401 ttgatcacta aatcttcttt gcaggcgaca gctctcttgc agcaccttaa acaatcgctg
    17461 gcaattacag gaaaattaca taatattcaa cgttctctgg acgatatctc ttcaggctct
    17521 attattcttc tggatatgat ggaagcggat aaaaagctta tccattattg gcaggatact
    17581 ttgagcagga aaaacaacaa tatcaaaata ttgttgctaa atacgcctga agattacccg
    17641 taccgcgaca ttgaaaactg gcctcatatc aacggcgttt tttattccat ggaggatcaa
    17701 gaacgtgttg tcaatgggtt gcaaggcgtc ctgcgcggcg aatgctactt tacgcaaaag
    17761 cttgccagct acctgattac gcattcaggt aactatcgtt ataacagcac ggaatcagcc
    17821 ctccttactc atcgggaaaa agagatcctg aataagctgc gtatcggcgc gtctaataac
    17881 gagatcgctc gttcgttgtt catcagcgaa aatacggtta aaacgcatct ttataatctt
    17941 ttcaagaaga tagccgtaaa aaaccggaca caagcggttt cctgggcaaa cgataacctc
    18001 aggcgataaa gccatgaaac gttatttacg ctggattgtg gcggcagaat ttctgttcgc
    18061 cgcagggaat cttcacgccg ttgaggtaga agtcccggga ttgctaactg accatactgt
    18121 ttcatctatt ggccatgatt tttaccgagc ctttagtgat aaatgggaaa gtgactatac
    18181 gggtaactta acgattaatg aaaggcccag tgcacgatgg ggaagctgga tcactataac
    18241 ggtcaatcag gacgttattt tccagacttt tttatttccg ttgaaaagag acttcgagaa
    18301 aactgtcgtc tttgcactga ttcaaactga agaagcacta aatcgtcgcc agataaatca
    18361 ggcgttatta agtacgggcg atttggcgca tgatgaattc taaataaaaa attgttcgga
    18421 ggctgcaatg cgtgtcaaac atgcagtagt tctactcatg cttatttcgc cattaagttg
    18481 ggctggaacc atgactttcc agttccgtaa tccaaacttt ggtggtaacc caaataatgg
    18541 cgctttttta ttaaatagcg ctcaggccca aaactcttat aaagatccga gctataacga
    18601 tgactttggt attgaaacac cctcagcgtt agataacttt actcaggcca tccagtcaca
    18661 aattttaggt gggctactgt cgaatattaa taccggtaaa ccgggccgca tggtgaccaa
    18721 cgattatatt gtcgatattg ccaaccgcga tggtcaattg cagttgaacg tgacagatcg
    18781 taaaaccgga caaacctcga ccatccaggt ttcgggttta caaaataact caaccgattt
    18841 ttaagcccca gcttcataag gaaaataatc atgcagcgct tatttctttt ggttgccgtc
    18901 atgttactga gcggatgctt aaccgccccg cctaaagaag ccgccagacc gacattaatg
    18961 cctcgtgctc agagctacaa agatttgacc catctgccag cgccgacggg taaaatcttt
    19021 gtttcggtat acaacattca ggacgaaacc gggcaattta aaccctaccc ggcaagtaac
    19081 ttctccactg ctgttccgca aagcgccacg gcaatgctgg tcacggcact gaaagattct
    19141 cgctggttta taccgctgga gcgccagggc ttacaaaacc tgcttaacga gcgcaagatt
    19201 attcgtgcgg cacaagaaaa cggcacggtt gccattaata accgaatccc gctgcaatct
    19261 ttaacggcgg caaatatcat ggttgaaggt tcgattatcg gttatgaaag caacgtcaaa
    19321 tctggcgggg ttggggcaag atattttggc atcggtgccg acacgcaata ccagctcgat
    19381 cagattgccg tgaacctgcg cgtcgtcaat gtgagtaccg gcgagatcct ttcttcggtg
    19441 aacaccagta agacgatact ttcctatgaa gttcaggccg gggttttccg ctttattgac
    19501 taccagcgct tgcttgaagg ggaagtgggt tacacctcga acgaacctgt tatgctgtgc
    19561 ctgatgtcgg ctatcgaaac aggggtcatt ttcctgatta atgatggtat cgaccgtggt
    19621 ctgtgggatt tgcaaaataa agcagaacgg cagaatgaca ttctggtgaa ataccgccat
    19681 atgtcggttc caccggaatc ctgacagata aaaaagccgg aattatcatc cggcatttta
    19741 ctgtttaagc gaaagcgtga gtgcccctca cgctttattt ttgatttcct gctcacggtg
    19801 cgccgtcttt gcactacgcg ccgccagcca caggccactg tttttcattg cgtaaccaaa
    19861 tatcagccca agcgccagcg aaggtaacac cagtttccag tcaccctgcc cggcaaacgt
    19921 cgcgcatgcg cctataaacg tccccggaac aaatgaaagc agcagctgtt tggcctgaat
    19981 acacatcaga aacgcgacaa taccggttat gacataaccg agaatttcca gatgtggtgc
    20041 cagtgcacta ccgtaaataa tgaccatcgc ccacaccacg ccactaagca gggttgcagc
    20101 ggagatcgcc agccctttca gcccaccttg cgggcaggca aagtaggccg tacagcccag
    20161 gaagcccgcc cagcttagta agcccaggga aacagccacc catccccaga taccggagag
    20221 aatgcctgtt gtgattgcaa tagagagaag tatgttcatg ccgcgcatga tagcagaaaa
    20281 cgcggccatg aatgagatcg agcacacatt ttatgcaaca acaaattatc cgttgcagtt
    20341 atgagtgacg tagatcacac ttattcttca gaatcttctt ccagctcgtc ccacattgca
    20401 ctaatggcat cgcgggttag cggtgccatg gtgcgccaga aaggcgtggt tgcatgggcc
    20461 tccactttgc caaggaacgc accacaccag ggtaacagat actcactgaa cagtgtttcc
    20521 agtgcttcgc tctcatcttc cgttgactga tcttccagcc aggaagctgc gagcagcaat
    20581 gtgccgatgt gatcggctgg cgtatccgct aatggcatcc ctcgctcaga aagaaaagcg
    20641 cgcacttccg cttccgtcgc gccctcaacc catgcgctac gatatggcgg cacagcacat
    20701 tcatcgccga taaacaacgc attgtaatcg gcagagactt gcgtcatatc acagcttttc
    20761 tgcaaacgtg tcagcaactc atcctgctcc agtggccagt tcgcagccag tttcccctca
    20821 cgaatcaggg taaacagcgg caccagtaaa ggatcttgtg gttggcggta atagagcgaa
    20881 cccagcacac gacagaggat agaaaactcg ttcattaata tatttccatt actagtaatt
    20941 aaaggtctgc aaattccgca atcggtgcca taccgcgaga ttcaaggaag ttcagtaagc
    21001 ggcgcggaga aacattcaaa atgcgctctg gcggaaaatc taccgcgtcg aggattttaa
    21061 gacactcttc aaattccccc atggtaaacg cggtgtgaga atccgagcct aatgccaccc
    21121 aacctccagc atcacgtacc gctgcggcta cctcacgaca gttgtcttca ctgcccttac
    21181 gtgagtgtaa aaatgaggaa ttattgattt ccagcgccac ctgatgtttc gcggctgctt
    21241 cagcaacggc tttcacatct atttcatatt tgggatttcc gggatggctt attatatgca
    21301 cattgccgct ggcgatagtg gcgatcatcg cttgtgtatt ggtcgctttg tcatgtggcg
    21361 caaaaaccgg ctcatgaaaa ccggcaataa ttagatccag cgagtcaaac attttaccgc
    21421 tgcagtcaat ttcaccatca acatttttaa tgttagcttc gatgccgcgc aggatcccta
    21481 ccccatcaac cactcgcggc cagatacgca tgttaatgaa gtgccagtga tgcggcgcat
    21541 cttccatatc cgggccatga tcggtgatcg caaaaagttt aatgcccttt tgtttggcct
    21601 gggcaatgta atcacttaat gtgctatatg catgtgtgct ggcaacggta tgcatatgaa
    21661 ggtcgacggg atacataact ctctcctgta ttcaattccc gccaaggata gcaggaatcc
    21721 tgatgcttta ttagtagccg cgtgcgcggt cgacttgccc gcagaccctc tccccttttt
    21781 cgagctgggc aatggtgcga gaaatgtact ccacagcttc agcgggacgg gtaatcgcgg
    21841 cgacatgtgg tgttatcgtc acgcgtggat gttgccagag cggactttca ggcggtaagg
    21901 gttcacgatt aaaaacatcc aacattgcgc ctttaacttt gccgctatcc agcgccgcga
    21961 gcaggtcatc ttccacaaca tgaacaccac gcgccaggtt gaggagatac gcgccatccg
    22021 gtaatttttc gagtaattgt tgattaataa tgccgacggt ttcaggggta ttcggtaaca
    22081 aattaatcaa tacccgacat tggctcagaa atgcagacag ttcttcccgt ccggcaaagc
    22141 tttgcacgcc aggccacgat ttacgggttc gactccagca acgcagcgga aagcgccagg
    22201 tttgcagact ctgagcaact ttactgccca gtacgcctgc gcccaaaatg ccgatggtaa
    22261 aatcttcccg atgatattca ggcagcggtt gccaatgcga actattttgc tggatgcgat
    22321 aatcgtcaaa acgtcgaaac caatgcagca cctgactgac agcatattcc tgcatttgct
    22381 cgcccatacc ggtatcttcc aggcgaaaaa gtggaacaga agggttcagc atttcagggt
    22441 gtgcctgtag cttgctcaaa atagaatcaa caccggcccc gagtgcgaac accgctttaa
    22501 gatcgcgccc tgccagcatt tcaacaggag gatgccagac taaagcataa tcagcagagt
    22561 cattatctcc gcttttccat gctctgactc ttgcctgagg aatagctttg cgcagtgcct
    22621 caatccacca ttgggtatcg aacgttgggt gataaaagat gatatccata ctgactcccg
    22681 aaaagcgttg tgcgaaattt attcgcactt atcgttatga tctacaaagg ccaccagcat
    22741 aacaaatccg tggtcggtgg caaaaaaagc agatttcgct tattaaaacc acacattgat
    22801 tgaagtttga ataaacgcgc gattttttca aaaagtttgt tgacctcagg tcatgatttc
    22861 cctaaattag cgcccgttcc agcaagacag gaacgacaat ttggtgaggt gtccgagtgg
    22921 ctgaaggagc acgcctggaa agtgtgtata cggcaacgta tcgggggt
//
LOCUS       DACAOP010000074        22931 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.074, whole genome shotgun sequence.
ACCESSION   DACAOP010000074 DACAOP010000000
VERSION     DACAOP010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22931
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.074"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..826
                     /locus_tag="IT892_003119"
     CDS             <1..826
                     /locus_tag="IT892_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310535.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3136307.1"
                     /translation="PAFVSKRIALLEQTLNVVLLHRTTRRVTITEEGERIYEWAQRIL
                     QDVGQMMDELSDVRQVPQGMLRIISFGFGRQVVAPALSALAKAYPQLELRFDVEDRLV
                     DLVNEGVDLDIRIGDDIAPNLIARKLATNYRILCASPEFIAQHGAPKHLTDLSALPCL
                     VIKERDHPFGVWQLRNKEGPHAIKVTGPLSSNHGEIVHQWCLDGQGIALRSWWDVSEN
                     IASGHLVQVLPEYYQPANVWAVYVSRLATSAKVRITVEFLRQYFAEHYPNFSLEHA"
     gene            953..1591
                     /gene="leuE"
                     /locus_tag="IT892_003120"
     CDS             953..1591
                     /gene="leuE"
                     /locus_tag="IT892_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HAP3136308.1"
                     /translation="MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGY
                     LAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGK
                     NSEAKSDEPQYGAIFKRALILSLTNPKAIVFYVSFFVQFIDVNAPHTGISFFILAATL
                     ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS"
     gene            1764..2123
                     /gene="yeaR"
                     /locus_tag="IT892_003121"
     CDS             1764..2123
                     /gene="yeaR"
                     /locus_tag="IT892_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
                     /protein_id="HAP3136309.1"
                     /translation="MLQIPQNYIHTRSTPFWNKQTAPAGIFERHLDKGTRPGVYPRLS
                     VMHGAVKYLGYADEHSAEPDQVILIEAGQFAVFPPEKWHNIEAMTDDTYFNIDFFVAP
                     EVLMEGAQQRKVIHNGK"
     gene            2127..2309
                     /locus_tag="IT892_003122"
     CDS             2127..2309
                     /locus_tag="IT892_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1869 domain-containing protein"
                     /protein_id="HAP3136310.1"
                     /translation="MGKATYTVTVTNNSNGVSVDYETETPMTLLVPEVAAEVIKDLVN
                     TVRSYDTENEHDVCGW"
     gene            2457..2705
                     /locus_tag="IT892_003123"
     CDS             2457..2705
                     /locus_tag="IT892_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP3136311.1"
                     /translation="MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTILLGIVGAVVGG
                     WISTLFGFGKVDGFNFGSFVVAVIGAIVVLFIYRKIKS"
     gene            complement(2764..2838)
                     /gene="yoaJ"
                     /locus_tag="IT892_003124"
     CDS             complement(2764..2838)
                     /gene="yoaJ"
                     /locus_tag="IT892_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YoaJ"
                     /protein_id="HAP3136312.1"
                     /translation="MKKTTIIMMGVAIIVVLGTELGWW"
     gene            complement(2841..2939)
                     /gene="yoaK"
                     /locus_tag="IT892_003125"
     CDS             complement(2841..2939)
                     /gene="yoaK"
                     /locus_tag="IT892_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family small membrane protein"
                     /protein_id="HAP3136313.1"
                     /translation="MRIGIIFPVVIFITAVVFLAWFFIGGYAAPGA"
     gene            complement(2972..3997)
                     /gene="dgcP"
                     /locus_tag="IT892_003126"
     CDS             complement(2972..3997)
                     /gene="dgcP"
                     /locus_tag="IT892_003126"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416308.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcP"
                     /protein_id="HAP3136314.1"
                     /translation="MSDQIIARVSQSLAKEQSLESLVRQLLEMLEMVTDMESTYLTKV
                     DVEARLQHIMFARNSQKMYIPENFTVSWDYSLCKRAIDENCFFSDEVPDRWGDCIAAR
                     NLGITTFLSTPIHLPDGSFYGTLCAASSEKRQWSERAEQVLQLFAGLIAQYIQKEALV
                     EQLREANAALIAQSYTDSLTGLPNRRAIFENLTTLFSLARHLNHKIMIAFIDLDNFKL
                     INDRFGHNSGDLFLIQVGERLNTLQQNGEVIGRLGGDEFLVVSLNNENADISSLRERI
                     QQQIRGEYHLGDVDLYYPGASLGIVEVDPETTDADSALHAADIAMYQEKKHKQKTPFV
                     AHPALHS"
     gene            4180..4434
                     /gene="yoaF"
                     /locus_tag="IT892_003127"
     CDS             4180..4434
                     /gene="yoaF"
                     /locus_tag="IT892_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing lipoprotein YoaF"
                     /protein_id="HAP3136315.1"
                     /translation="MKIISFVLPCLLVLAGCSTPSQPEAPKPPQIGMANPASVYCQQK
                     GGTLIPVQTAQGVSNNCKLPGGETIDEWALWRRDHPAGEK"
     gene            complement(4456..4803)
                     /locus_tag="IT892_003128"
     CDS             complement(4456..4803)
                     /locus_tag="IT892_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416306.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HAP3136316.1"
                     /translation="MNIQCKRVYDPAEQSDGYRILVDRLWPRGIKKTDLALDEWDKEI
                     TPSTELRKAFHGEVVDYATFREQYLAELAQHEQEGKRLADIAKKQPLTLLYSAKNTTQ
                     NHALVLADWLRSL"
     gene            complement(4858..6039)
                     /gene="nimT"
                     /locus_tag="IT892_003129"
     CDS             complement(4858..6039)
                     /gene="nimT"
                     /locus_tag="IT892_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-nitroimidazole transporter"
                     /protein_id="HAP3136317.1"
                     /translation="MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAY
                     SLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPY
                     LLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
                     LNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTL
                     FLGINSLVYYVIIGWLPAILISHGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQ
                     RGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLTFIGLRASSAHQAA
                     ALSGMAQSVGYLLAACGPPLMGKIHDANGNWSVPLMGVAILSLLMAIFGLCAGRDKEI
                     R"
     gene            6136..6957
                     /locus_tag="IT892_003130"
     CDS             6136..6957
                     /locus_tag="IT892_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP3136318.1"
                     /translation="MMHRLNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLI
                     LALHGAITCTVENALWMVPPQYAVWIPGGVEHSNQVTANAELCFLFIEPSAVTMPTTC
                     CTLKISPLCRELILTLANRTTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPVSSHPKI
                     RTMVEMMAKGPVEWGALGQWAGFFAMSERNLARLIVKETGLSFRQWRQQLQLIMALQG
                     LVKGDTVQKVAHTLGYDSTTAFITMFKKGLGQTPGRYIARLTTVSPQSAKPDPRQ"
     gene            complement(6914..7360)
                     /locus_tag="IT892_003131"
     CDS             complement(6914..7360)
                     /locus_tag="IT892_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAP3136319.1"
                     /translation="MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFP
                     WIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRG
                     VTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ"
     gene            7530..7634
                     /locus_tag="IT892_003132"
     CDS             7530..7634
                     /locus_tag="IT892_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416302.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136320.1"
                     /translation="MNDQMFVETLIITSSFFAIAVVLVLSVLLIERTG"
     gene            complement(7635..8138)
                     /gene="yeaK"
                     /locus_tag="IT892_003133"
     CDS             complement(7635..8138)
                     /gene="yeaK"
                     /locus_tag="IT892_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mischarged aminoacyl-tRNA deacylase"
                     /protein_id="HAP3136321.1"
                     /translation="MTEMAKGSVTHQRLIALLSQEGADFRVVTHEAVGKCEAVSEIRG
                     TALGQGAKALVCKVKGNGVNQHVLAILAADQQADLSQLASHIGGLRASLASPAEVDEL
                     TGCVFGAIPPFSFHPKLKLVADPLLFERFDEIAFNAGMLDKSVILKTADYLRIAQPEL
                     VNFRRTA"
     gene            complement(8181..9671)
                     /locus_tag="IT892_003134"
     CDS             complement(8181..9671)
                     /locus_tag="IT892_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HAP3136322.1"
                     /translation="MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQ
                     KADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTAHK
                     YPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDL
                     NDRYVYFYEPVNVEYFAMNNWSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQN
                     VMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIII
                     NQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHF
                     RLYQNVSRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDT
                     LGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRL
                     QHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS"
     gene            complement(9852..11327)
                     /locus_tag="IT892_003135"
     CDS             complement(9852..11327)
                     /locus_tag="IT892_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HAP3136323.1"
                     /translation="MIQSTRISMGLFFKYFLSLTKIDPGQNYISLPSIKSSTHIALLF
                     MVSMGTQKLKAQSFFIFSLLLTLILFCITTLYNENTNVKLIPQMNYLMVVVALFFLNA
                     VIFLFMLMKYFTNKQILPTLILSLAFLSGLIYLVETIVIIHKPINGSTLIQTKSNDVS
                     IFYIFRQLSFICLTSLALFCYGKDNILDNNKKKTGILLLALIPFLVFPLLAHNLSSYN
                     ADYSLYVVDYCPDNHTATWGINYTKILVCLWAFLLFFIIMRTRLASELWPLIALLCLA
                     SLCCNLLLLTLDEYNYTIWYISRGIEVSSKLFVVSFLIYNIFQELQLSSKLAVHDVLT
                     NIYNRRYFFNSVESLLSRPVVKDFCVMLVDINQFKRINAQWGHRVGDKVLVSIVDIIQ
                     QSIRPDDILARLEGEVFGLLFTELNSAQAKIIAERMRKNVELLTGFSNRYDVPEQMTI
                     SIGTVFSTGDTRNISLVMTEADKALREAKSEGGNKVIIHHI"
     gene            complement(11474..12757)
                     /locus_tag="IT892_003136"
     CDS             complement(11474..12757)
                     /locus_tag="IT892_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
                     /protein_id="HAP3136324.1"
                     /translation="MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVT
                     DVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQ
                     GQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGV
                     PANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAE
                     LRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILL
                     YLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNP
                     AQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHL
                     QSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKG"
     gene            complement(12870..14804)
                     /gene="yeaG"
                     /locus_tag="IT892_003137"
     CDS             complement(12870..14804)
                     /gene="yeaG"
                     /locus_tag="IT892_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YeaG"
                     /protein_id="HAP3136325.1"
                     /translation="MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLM
                     AIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEK
                     KQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQI
                     LEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDEN
                     NQDISALVGKVDIRKLEHYAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLL
                     TATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLR
                     ISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGES
                     LKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVL
                     EQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVT
                     YADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARAN
                     NSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKG
                     YTRKQVRLLCEWYLRVRKSS"
     gene            15240..15986
                     /locus_tag="IT892_003138"
     CDS             15240..15986
                     /locus_tag="IT892_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MltA-interacting protein"
                     /protein_id="HAP3136326.1"
                     /translation="MTKLKLLALGVLIATSAGVAHAEGKFSLGAGVGVVEHPYKDYDT
                     DVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSITAYWSPLYFKAKDSGDHQMRHL
                     DDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGI
                     GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTAR
                     YTRLSDEVTDSPMVDKSWTGLISTGITYKF"
     gene            16076..16930
                     /gene="yeaE"
                     /locus_tag="IT892_003139"
     CDS             16076..16930
                     /gene="yeaE"
                     /locus_tag="IT892_003139"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal reductase YeaE"
                     /protein_id="HAP3136327.1"
                     /translation="MQQKMIQFSGDVSLPAVGQGTWYMGEDASQRKTEVAALRAGIEL
                     GLTLIDTAEMYADGGAEKVVGEALTGLREKVFLVSKVYPWNAGGQKAINACEASLRRL
                     NTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
                     CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHA
                     HNISAAQVLLAWVISHQGVMAIPKAATIAHVQQNAAVLEVELSSAELAMLDKAYPAPK
                     GKTALDMV"
     gene            complement(16978..17862)
                     /locus_tag="IT892_003140"
     CDS             complement(16978..17862)
                     /locus_tag="IT892_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416294.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
                     /protein_id="HAP3136328.1"
                     /translation="MIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQG
                     AHLLSWKPAGEEEVLWLSNNTPFKNGVAIRGGVPVCWPWFGPAAQQGLPAHGFARNLP
                     WTLKSHHEDADGVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLESHGEFETT
                     SALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKENVLTDGIQTFPDRTDRVYLNPQDCS
                     VINDEALNRIIAVGHQHHLNVVGWNPGPALSISMGDMPDDGYKTFVCVETAYASETQK
                     VTKEKPAHLAQSIRVAKR"
     gene            complement(17946..18941)
                     /gene="gapA"
                     /locus_tag="IT892_003141"
     CDS             complement(17946..18941)
                     /gene="gapA"
                     /locus_tag="IT892_003141"
                     /EC_number="1.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP3136329.1"
                     /translation="MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYM
                     LKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLT
                     DETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAK
                     VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKV
                     LPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTE
                     DDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK"
     gene            19283..19696
                     /gene="msrB"
                     /locus_tag="IT892_003142"
     CDS             19283..19696
                     /gene="msrB"
                     /locus_tag="IT892_003142"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAP3136330.1"
                     /translation="MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVY
                     HCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHL
                     GHVFPDGPQPTGERYCVNSASLRFTDGENGEEING"
     gene            19738..20010
                     /locus_tag="IT892_003143"
     CDS             19738..20010
                     /locus_tag="IT892_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416291.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaC family protein"
                     /protein_id="HAP3136331.1"
                     /translation="MNLDDIINSMMPEVYQRLSTAVELGKWPDGVALTEEQKENCLQL
                     VMLWQARHNIEAQHMTIDTNGQMVMKSKQQLKEDFGISAKPIAMFK"
     gene            20380..21456
                     /locus_tag="IT892_003144"
     CDS             20380..21456
                     /locus_tag="IT892_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HAP3136332.1"
                     /translation="MKALARFGKAFGGYKMIDVPQPMCGPEDVVIEIKAAAICGADMK
                     HYNVDSGSDEFNSIRGHEFAGCIAQVGEKVKDWKVGQRVVSDNSGHVCGVCPACEQGD
                     FLCCTEKVNLGLDNNTWGGGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPIC
                     NAYKSIAQQSKFLPGQDVVVIGTGPLGLFSVQMARIMGAVNIVVVGLQEDVAVRFPVA
                     KELGATAVVNGSTEDVVARCQQICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRV
                     GMGFKPLDFSINDITAWNKSIIGHMAYDSTSWRNAIRLLASGAIKVKPMITHRIGLSQ
                     WREGFDAMVDKTAIKVIMTYDFDE"
     gene            21483..22862
                     /locus_tag="IT892_003145"
     CDS             21483..22862
                     /locus_tag="IT892_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136333.1"
                     /translation="MEQITKPHCGARLDRLPDCRWHSSMFAIVAFGLLVCWSNAVGGL
                     ILAQLKALGWTDNSTTATFSAITTAGMFLGALVGGIIGDKTGRRNAFILYEAIHIASM
                     VVGAFSPNMDFLIACRFVMGVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSY
                     PLCSLIAMGLTPLISAEWNWRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEA
                     EKVMRSIEEGVIRQTGKPLPPVVIADDGKAPQAVPYSALLTGVLLKRVILGSCVLIAM
                     NVVQYTLINWLPTIFMTQGINLKDSIVLNTMSMFGAPFGIFIAMLVMDKIPRKTMGVG
                     LLILIAVLGYIYSLQTSMLLITLIGFFLITFVYMYVCYASAVYVPEIWPTEAKLRGSG
                     LANAVGRISGIAAPYAVAVLLSSYGVTGVFILLGAVSIIVAIAIATIGIETKGVSVES
                     LSIDAVANK"
BASE COUNT         5985 a         5343 c         5631 g         5972 t
ORIGIN      
        1 accggcgttc gtcagcaagc gcatcgcctt gctggagcaa acgctaaacg tggtgttgtt
       61 acaccgcacc acccgccgcg tcaccattac cgaagaagga gagcggattt atgaatgggc
      121 gcagcggatt ttgcaggatg tcggtcagat gatggacgaa ctttctgacg tgcgtcaggt
      181 gccgcagggg atgctgcgta ttatcagctt tggttttgga cgacaggtgg tggctccggc
      241 gttatcagcg ctggcgaagg cgtatccgca actggaatta cgttttgatg tggaagaccg
      301 actggtcgat ttggtcaatg aaggtgtcga tctcgatatt cgcattggcg atgacatcgc
      361 ccctaattta atcgcccgca aactggcgac caattaccgt attctctgcg cgtcgccgga
      421 atttattgcg caacatggcg cgccgaaaca tttaaccgat ctttctgcat tgccgtgcct
      481 ggtcattaaa gagcgcgatc atccttttgg tgtctggcaa ttacgcaata aagaaggtcc
      541 ccatgcgatt aaagtcaccg gcccactgtc gtctaatcat ggagaaattg tccatcagtg
      601 gtgtctcgat gggcagggga ttgctctgcg ttcctggtgg gatgttagcg aaaacattgc
      661 cagtggtcat ttagtgcaag tgctaccgga atattaccag ccagcgaacg tctgggccgt
      721 ttatgtttca aggctggcga cgtcagcgaa agtgcggata acggtagaat ttttacgcca
      781 gtattttgcc gagcactacc cgaatttttc actggagcat gcctgattaa tgattcaatt
      841 atcgggttga tatcaggtta aaacctgatt ttctcctttc taagccgcta cagattggtt
      901 agcatattca cctttaatcg cgcatgatcg aaagataatt aaagaggtta atgtgttcgc
      961 tgaatacggg gttctgaatt actggaccta tctggttggg gccattttta ttgtgttggt
     1021 gccagggcca aataccctgt ttgtactcaa aaatagcgtc agtagcggta tgaaaggcgg
     1081 ttatcttgcg gcctgcggtg tatttattgg cgatgcggta ttgatgtttc tggcatgggc
     1141 tggagtggcg acattaatta agaccacccc gatattattc aacattgtac gttatcttgg
     1201 tgcgttttat ttgctctatc tggggagtaa aattctttac gcgaccctga agggtaaaaa
     1261 tagcgaggcc aaatccgatg agccccaata cggtgctatt tttaaacgcg cgttaatttt
     1321 gagcctgact aatccgaaag ccattgtgtt ctatgtgtcg tttttcgtac agtttatcga
     1381 tgttaatgcc ccacatacgg gaatttcatt ctttattctg gcggcgacgc tggaactggt
     1441 gagtttctgc tatttgagct tcctgattat atctggtgct tttgtcacgc agtacatacg
     1501 taccaaaaag aaactggcta aagttggcaa ctcactgatt ggtttgatgt tcgtgggttt
     1561 cgctgcccga ctggcgacgc tgcaatcctg atgctttcag cccgcgttgt cgcgggcttc
     1621 ccatctataa tcctccctga ttcttcgctg atatggtgct aaaaagtaac caataaatgg
     1681 tatttaaaat gcaaattatc aggcgtaccc tgaaacggct ggaataaacc gttttcagcg
     1741 cattcaccga aggagggaaa aggatgcttc aaatcccaca gaattatatt catacgcgct
     1801 caacgccttt ctggaataaa caaactgcac ctgccggaat attcgaacgt catcttgata
     1861 aaggaacgcg cccgggggtt tacccacgcc tttccgttat gcatggggcg gtcaaatatc
     1921 tcggctacgc tgatgaacac agtgcagagc ctgatcaggt gatccttatc gaagcggggc
     1981 agtttgcggt gttccctcca gaaaagtggc acaacattga agccatgact gacgatactt
     2041 atttcaacat tgacttcttc gtggctcctg aagtcctgat ggaaggtgcg caacaacgga
     2101 aagtcattca taacgggaaa tgaatcatgg gcaaagcaac gtataccgtg accgtcacca
     2161 ataacagcaa tggcgtttct gtcgattatg aaacagagac gccgatgact ttgctggtgc
     2221 cagaagtggc ggctgaagtg ataaaagatc tggtgaatac cgtacgttct tatgacacgg
     2281 aaaacgaaca tgatgtttgt ggttggtaat tatcactgat cgttgatggc gcaatttctg
     2341 cgccatcgca aaaaaaacct ccgtgatgct cgtcacaaat cttgccctcc cgatgttgtg
     2401 ctatgctttt tatcagcgac taacccgcta atgcaaaaca gataagtgag gaaacaatgg
     2461 gcattctgtc atggattatt tttgggctta ttgccggtat tctggcgaag tggatcatgc
     2521 caggtaaaga tggaggtgga ttctttatga ctatcctgct ggggatagtc ggtgccgtag
     2581 tcggcggatg gatcagcacg ctgtttggct ttggtaaagt cgatggcttc aattttggca
     2641 gcttcgtggt tgccgttatt ggtgcgattg tcgtgctatt tatctacagg aagattaaaa
     2701 gttaacgctt aaattgcaca aaggctgcac acaggcagcc tttgctattt tttagaggtg
     2761 acgttaccac catcccagct cagtgccgag tacgacaata atcgccacac ccatcataat
     2821 aatcgttgtt tttttcatct ttatgctccc ggggcagcat agccgccaat aaaaaaccat
     2881 gctaaaaata cgaccgctgt aatgaagatt acaaccggaa aaataatacc gattcgcatg
     2941 ttatcaccaa tcaaaaggat gtgaatacgc ctcaggaatg tagcgctgga tgcgcgacaa
     3001 aaggtgtttt ctgtttgtgt tttttctcct gatacatcgc aatatcggca gcatgcaggg
     3061 cactgtctgc atcggttgtt tcaggatcga cttctactat gccaagactg gcaccgggat
     3121 aatacaaatc aacatcacct aagtgatatt ctccacgtat ttgctgctga atgcgttctc
     3181 gcagcgacga aatatccgca ttctcgttgt ttagtgaaac aactaaaaac tcatcaccgc
     3241 cgagacgacc aataacttcg ccattttgct ggagcgtatt aaggcgctcg ccaacctgaa
     3301 tgagaaacag atcgccacta ttatgaccaa aacgatcatt gattaatttg aagttatcca
     3361 gatcgataaa cgcgatcatt atcttatggt taagatgccg ggcgagggaa aacagtgtcg
     3421 tcagattttc aaaaatcgcc cgccgattcg gtagcccggt taacgagtcg gtatacgatt
     3481 gcgcaatcag cgcagcattg gcttcgcgca gctgttcaac cagtgcctct ttttgaatat
     3541 attgtgcaat cagtccggcg aataactgta aaacctgttc cgcgcgttca ctccactggc
     3601 gcttctcact gctggcggcg caaagcgtgc catagaatga tccatccggt aagtgaattg
     3661 gcgtgctcag aaatgtggtg atgccaagat tgcgtgccgc aatacagtca ccccaacggt
     3721 cggggacttc atcgctgaaa aagcagtttt catcaatggc gcgtttgcat aacgagtaat
     3781 cccacgagac ggtaaaattc tccgggatgt acattttctg gctgttacgg gcaaacataa
     3841 tatgctgcag gcgcgcttcg acatccactt tggtcaggta ggttgattcc atatcagtga
     3901 ccatttccag catctccaga agctgtcgga ccagactttc cagtgactgt tctttggcaa
     3961 gggattgcga gacgcgggcg ataatctgat ctgacacgga acaactccag gatacggcgg
     4021 gtaaatgctg attatttaat ctttgcaggc atgataaaac atcatcaaca aagatgaaac
     4081 aagacgtaat atgttttgag tgaatgtaat aaaaatagtg ctgcaaaaca aaacgatacc
     4141 gcgatactct aatcttggat aaatatgtga gatcaataaa tgaaaattat cagttttgtt
     4201 ctgccttgct tgctggtcct ggctggttgt tcaacccctt ctcagccaga agcacctaaa
     4261 ccgccgcaga ttggtatggc aaatccggcg tcggtctatt gccagcagaa gggcgggacg
     4321 ctcattccag tgcagacagc gcaaggggtc agcaacaatt gcaaattacc gggcggtgaa
     4381 acgattgatg aatgggcatt gtggcggcgt gaccatccgg ctggtgaaaa ataaccgccg
     4441 gatgctgtac taaaatcaca agctacgtag ccagtcggcc agcaccagcg catggttctg
     4501 cgtggtgttt tttgctgagt agagcagggt cagcggctgt tttttggcga tgtccgccag
     4561 ccgctttcct tcttgctcgt gttgcgccag ttctgcaaga tattgctcgc gaaaggttgc
     4621 ataatcgacg acttcgccgt gaaaggcttt gcgcagttcc gttgacggcg tgatttcttt
     4681 atcccactca tcaagggcta aatcggtttt tttgataccg cgcggccaga ggcggtcgac
     4741 cagtatgcga taaccatcgc tctgttcagc cggatcataa acgcgtttgc actgaatatt
     4801 catcgtgttt gttctccctt tcacgcatga tttgttacgt cactatagca ccggatatta
     4861 gcgaatttct ttgtctctcc cggcgcaaag tccgaaaatc gccatcagta gtgaaagtat
     4921 ggcaacaccc ataagtggta cagaccagtt accgttagca tcgtgtattt tacccatcag
     4981 cggcggccca caggctgcca acaaataccc gacggattgt gccatccccg agagtgccgc
     5041 cgcctgatgc gcagaactag cccgcagacc aatgaacgtc aaccccagta tcattgttgc
     5101 gccggaacca aaaccgaaaa gcagagtcca ggtgatcgcg tgcgctggca taaagcagag
     5161 cccaaccgcg cccactgcgc acatcaaggc aacgaacgct gcaataccac gctgatcttt
     5221 cacatgatgt aagaaaagtg ggatcagcaa accgggtgct gctgtggcta gttgcagcaa
     5281 accatgcagt gaacccgcct gtgcttcgct atagccgtga ctgatgagga tcgccggaag
     5341 ccagccaata atcacgtaat agaccagtga gttgatccca agaaacaatg tgacctgcca
     5401 ggcaagcggc gaacgccaga taccccgagt atgtaaggcg cgcgaggtac tcaaatttgc
     5461 atgttgttga cttcgccact gtggcagcca taaaaaaaga gccagcagag gaaaacacat
     5521 cagcatgagc aacgcgcctt gccagccaaa accgttcaaa gccagcggca cgaccatagc
     5581 cgatcccagt gccgctgcag ctcccattgt cagggaatat gcgccggtaa gtctggcgac
     5641 ggaatgaggg aaatcgcgtt taattaatcc tggcagtaag acattgccta atgcaatccc
     5701 accgccaatg accgctgtac cgccaaataa taagtaaggc gaagggagag agcgaattgc
     5761 gataccagca cagatcaaaa gtaacgcggc aaacaggcta cgttccatac caaaacgtcg
     5821 cgctaccggg gcagccaaag gtgagattag cgcaaaggcc aataatggca gggtggtcaa
     5881 taagccggtt tgcgctgtcg tcagcgagta agcggaacga atcgtatcca gtaacggtgc
     5941 tgcgccggta aaggtgacgc gtaatgttgt ggcaatcatc agaatgccag cgataaggac
     6001 aatcctgttt ttgccgctta atgaagttga acaggtcata tgcttctcat tgttacaaac
     6061 gaggctgtac cttaccgttt ttattgttat gttgaatcaa gctaaaatga caaattatcg
     6121 ctaagttcgg acaaaatgat gcacaggttg aatctcaatg gctatgaacc cgaccgacac
     6181 catgaagccg cggtcgcatt ttgtattcac gccggaacgg atgagttaac cagtcctgta
     6241 catcagcacc gcaaaggaca gctgatactg gcgctacatg gtgcaattac ctgtacggtg
     6301 gaaaatgctt tgtggatggt gccgccacaa tatgcggttt ggataccggg cggggtggaa
     6361 catagcaatc aagtaacagc taatgctgaa ctctgttttc tgtttatcga acccagcgca
     6421 gtgacaatgc cgacaacatg ttgcacattg aaaatatcgc ccttatgccg ggaattaatt
     6481 ttaaccctgg caaacaggac gacgactcag cgtgctgagc caatgacccg cagattaatt
     6541 caggtcctgt ttgatgaact ccctcagcag ccacaacaac agctgcacct gcccgtttct
     6601 tctcatccta aaatccgcac gatggtggag atgatggcga aagggcctgt cgagtggggg
     6661 gcattggggc aatgggctgg cttttttgcg atgagtgaac gcaatcttgc ccgactgata
     6721 gtaaaagaga cggggttgag ttttcgccag tggcgtcagc agttacagct gattatggcg
     6781 cttcagggat tagtgaaagg cgatactgta cagaaagttg ctcatacgct ggggtatgat
     6841 tcaacaacgg cctttattac tatgtttaag aaaggcctgg ggcaaacgcc aggccgatat
     6901 attgcgagat taactactgt ttccccacaa tcagcgaaac cagacccgcg gcaataagcg
     6961 gcccaaccgg tacgccgcga aacagcgcta cgcctaaaac agtgcctacc agcagcccgg
     7021 cgaccagttg cggctggctg cccattaacg tcacgccgcg cccacccagc caggagacaa
     7081 tcacgcctac tgcaatcgcc accagtgatt tccagttcag aaacgagtga atcaaggttg
     7141 agggcggtag cgtcccgctg gcgatggggg ccataacgcc aatcgtcaga atgattatcc
     7201 cgatacttag cccctgtttt tcaatccacg gaaaaaaggt gcttaacggt gtgacgcgga
     7261 caatgattaa caccagaatt gaaacggcga cagtggtgtt atgactgata aagcccagcg
     7321 cagctaaccc gagcaggatc agcaaagtga catcaaacat cgtggtttcc ttgccaaaaa
     7381 ataataagcc tgcttacttt acgcttgctg caggaaggaa gtagaaaatc tttacgtttt
     7441 ttgcataaaa aatcaggcga actgtcatca aactgccatt tgtgcacgct aacaataacg
     7501 tgaaaacagc tatctcccgg gggcatgcta tgaacgatca aatgtttgtc gagacactga
     7561 ttatcacgtc atcgtttttt gccattgctg ttgtactggt tttgtccgtt cttcttatcg
     7621 aacggaccgg ctagttacgc agtgcggcgg aaattgacca gttctggttg cgcaatgcgc
     7681 aaataatccg cggttttcaa aataacggat ttatccagca tgcctgcatt gaaggcgatt
     7741 tcatcaaatc gttcgaagag tagagggtcg gcaaccagtt tgagttttgg atggaagctg
     7801 aaagggggga tcgcgccgaa gacacagcct gtgagttcat cgacttccgc cgggctggcc
     7861 aacgaagcgc gtaatccgcc tatatggctg gcgagttggc tcagatcggc ctgttgatcg
     7921 gctgcgagga tcgccagaac atgttgattt acgccattgc ctttgacttt acataccagt
     7981 gccttagcac cctggcctag agcggtgcca cgaatttctg acaccgcttc acatttacct
     8041 accgcttcat gggtaacgac gcggaagtca gcaccttctt gtgataataa agcgattaac
     8101 cgctgatgcg tcacgcttcc tttagccatt tcagtcattt cacgctcctg agattacaag
     8161 caaacaacca cagaaggtta tcatgaacgg ctgtttttgt tctgcttatt gacatataaa
     8221 cgctcatcgg aagctttata cgcatcatgt aacgtatcgt tttctttcat cgcgtaaata
     8281 ccggaagaga agccgatctc tttctgcggc gcgatatgtt gcagacgttt ttcgatacgt
     8341 tcaggcagtt gtgctgcaat ttgcggcgtc gaatcgacaa gaatgatgca gaattcatcg
     8401 ccaccgagtc ggatggcata atcactttta cgaatcgact gtttaatcgc ctgagctaat
     8461 aacgtaatcg ctaaatcccc ctcctgatga ccgagggtgt catttatttg ctttaacttg
     8521 tccatgtcaa tagcaataaa catcaccgaa gaaccggatt gcaccagttt ctgcaaccgc
     8581 tgctccagtt caggggttaa aattttgcga ttatacagtc cagtcatcgc atcactaata
     8641 ttttctcgcg acacattttg gtataaacgg aagtgcatcc gcaccatatt cagcaaaatt
     8701 aacgccgtca aaatccagaa cagaacgctt ttccacgaag acgtgataaa gtaaagaata
     8761 tcaatggata acgagacacg aatgccgccc ggtaagtcat ggacgtaact gacatactgg
     8821 aacagattat cttcgctctg gttgatgata atgtcgcgcc ccgaatcggt atcggttagc
     8881 gtgacattga gaaaacgcca gaggagaggg cggtcatgag tataaaagat attccgcaga
     8941 ttgtttttgt taatatccag cagcacaatc ccttttagct gccctgcgac atataccggc
     9001 gtcagcaaac tcatcacgtt ctgtttagta cgctgatcct ggtaaatgct cgacaatacg
     9061 gtacgcccgg taaatacctt ttcaatatct ttgcgatcga tgccaatact tcctgactgc
     9121 aggaaggacc agttattcat cgcaaagtat tcaacattaa ccggctcata aaaatagaca
     9181 tagcggtcat tgagatcgag ataatagtga aatttctctt cggccatccc aagacctgaa
     9241 ccgtaatcat cctggtggcg gttgccttcc actgcctgat caaaagcggg taatagtgct
     9301 gcagcttcca caattgtgtc gcagtcagtg gatgcggttt gtagtgtgcc gcgtaagccc
     9361 gggtatttat gggcagtcag gtttaagcca tgggtgttat tggcagactc aaaagcctcg
     9421 cagatggcgc gccgctgttc tggcgacact tccgactgct cagcagcgag agcgcgcatc
     9481 acatgcgcgg caatactctg attctgatac ttatcataaa gaaaggagga gtctgctttc
     9541 tgcacgatat agcgcagata ggcactcatt gctctgtcgc tggcgacaag ttcaaaaata
     9601 aggaaggaag atgtcagcac aatgacactt gcggcgataa aatgccggag cattctatgg
     9661 tgcaatttca tgataaatgg cactccttcg gttagtgaaa cgagaaaacc agataaagtt
     9721 cgattgcggc ctggcacagg ggcgctaatt atactcatct ctgcgccgct ggggagggga
     9781 aatttagggg taatagtaat aaattgtatg caaaagccac gcaaaaagca tggctctgaa
     9841 tatttttgca cttaaatatg atgaataatc actttgttgc ccccctcgct tttcgcttcg
     9901 cgtaaggctt tatctgcttc cgtcatgaca agcgagatat tacgcgtgtc acccgttgaa
     9961 aaaaccgtgc caatactgat ggtcatttgt tcaggaacat catatctgtt actaaagccg
    10021 gtcaggagtt cgacattttt acgcatacgt tccgcaatga tttttgcctg ggcactattg
    10081 agttcggtaa atagcaagcc aaacacctca ccctccagtc gcgctaaaat atcatcgggg
    10141 cggatgcttt gctggataat atcgacaatt gaaaccagca ctttatcacc cacacgatgt
    10201 ccccattggg cattgatgcg tttgaactga ttaatatcaa ccagcatgac acagaagtcc
    10261 ttaacaacag gtcgcgacaa taatgactct acgctgttga aaaagtagcg ccgattataa
    10321 atattggtca gcacatcatg aactgccagt ttgctggaga gttgcagctc ctgaaaaatg
    10381 ttataaatca gaaaagacac aacaaacagt ttactggaaa cttcaatccc gcgactgata
    10441 taccagatag tataattata ctcatccaga gtcagtagaa gtaagttgca gcatagcgat
    10501 gccagacata ataatgctat taacggccat agttcgctgg ctaatcgtgt gcgcatgata
    10561 ataaagaaca gtaaaaatgc ccacagacaa accaatattt ttgtatagtt gattccccag
    10621 gtcgcagtat ggttgtccgg acagtaatcg acgacataca aagaatagtc agcgttataa
    10681 ctgctcagat tgtgtgccag aaggggaaaa actaaaaaag ggatcagcgc cagcaacagg
    10741 attcccgttt ttttcttatt gttgtcaagg atgttgtctt ttccataaca aaagagcgcc
    10801 agcgaggtta aacaaataaa actgagttgg cggaaaatat agaaaataga aacatcattc
    10861 gactttgtct ggatcagtgt actgccgtta attggtttat ggataattac aatggtttca
    10921 actaaataga taaggccact taaaaatgca aggcttaaaa tgagtgttgg taaaatttgt
    10981 ttgttagtga aatatttcat taacatgaaa agaaaaatga cggcgttaag gaaaaacaaa
    11041 gccacaacaa ccatcaggta attcatctgt gggatgagtt ttacatttgt gttttcgtta
    11101 tataaggtag taatgcaaaa taaaattaac gtcagcaata aactgaaaat aaaaaagctt
    11161 tgagctttta atttttgtgt acccatagaa accataaaaa ggagagcaat gtgggtgctg
    11221 gattttattg atggcagaga tatatagttt tgaccaggat caattttcgt taacgataaa
    11281 aaatatttaa agaataaccc catggaaata cgtgttgact gaatcatttt tccgaatgat
    11341 tgttttctgg aactaaatta tgtaaaggtt atgctgtcat atttaaagcg attgtaagct
    11401 aatgtatgta ataaatgaga taatttacag taagctaaaa atcagccagg cgataatgac
    11461 ctggctgata gttttagcct ttagctgttg cattttgttt atgaaacagt tcacggaaca
    11521 ccggataaat atcatcctgg tcgcggatgt gctgcatcgc aaagttgtcg aaagtagatt
    11581 gcagatgctc atattctcgc cacaatgtct gatgtgcacg acgggtaatt tcgatatagc
    11641 tgtaataacg aacaacaggt aataattttt tcgccaggat ttcatggcaa agcggagagt
    11701 catcggccca gttatcgccg tccgatgctt gtgcagcgta aatattccac tgtgccgggt
    11761 tataacgctc tttcactacc tcatccatca gtttcagggc gctggaaaca atggtgccgc
    11821 ctgtttcctg cgagtagaaa aactcatgtt catcgacttc tttcgcctgg gtatgatggc
    11881 ggatgtatac gacttccacg ttcttatacg ttctgctgag gaacagatac agcagaatat
    11941 aaaaacgctt agccatatct ttagtggatt gatccattga accggaaacg tccatcaggc
    12001 aaaacatcac tgcctggctg gagggatcgg gccgcttctc gtagttcttg taacgtaaat
    12061 cgaaggtgtc aataaaaggg acgcgttcaa ttttggcacg taattctgca atttctttgc
    12121 gcagacgttc ctcttccagc agttgcgcag gttcactgtt gctgatgatg gccaaattct
    12181 cttccagtgc atgaagttcc cgccgcttgc ctgccgtcat ggctgtgcgt cgcgccagtg
    12241 agttctgcaa tgaacgcaca acgctgatat tggccggaac gccgttagcg gtataacccg
    12301 cccgatgcgt tttatattcg gtcagctggc gttgttggtt ttgtttcaga ttcggtaagg
    12361 ccaaatcttc aaagagcaga tcaagatact catctttcga aatctgaaag acaaattcat
    12421 cctgaccttc accatcctgg ctggcctggc cctgaccact gccggaacct ccgccgccac
    12481 cctggggacg ttcaattcgg tcgttctgga cgaaatggtc attgcccgga tgcacgcggt
    12541 ggcgcagacc gccacgcccc tgatgaaaca tcggttcgct aatatcttcc gtgggaatgg
    12601 atacggattc gccgctgtcg acgtcagtca ccgaacgctt attaatggcc tcggagatcg
    12661 actgtttaat ttgcgcttta taacggcgta aaaaacgctg gcgattcacc atgcttttgt
    12721 ttttgccgtt cagacgccgg tcaataaacc aggtcatatg ccccccgtac tacatttgcc
    12781 aactgtatgc tacgcctgtg ttgccgcttc tcaggcccac ggttcgctgt cgttgtaggc
    12841 ccggtaacat gtgtaccggg ccagggttgt taagacgatt tacgtacgcg caaataccat
    12901 tcgcacagta aacgcacctg tttacgggtg tagccttttt ccatcatacg gtcgacaaag
    12961 tcgtcgtgtt tcttctgctc gtcggttgac gttttggcgt taaacgagat aaccggcaac
    13021 agctcctcgg tattggagaa cattttcttc tcgatgaccg tgcgcagttt ttcatagctg
    13081 gtccagttcg gattgcgtcc gctgttattc gctctggcgc gcagtacgaa gttaacaatc
    13141 tcgttgcgga aatcttttgg attactgatc cccgccggtt tctcgatttt ctccagctcg
    13201 gcgttaagag actcgcggtc aaacagctgc ccggtatccg gatcgcgata ctcctgatcc
    13261 tgaatccaga aatccgcgta ggtaacataa cggtcgaaaa tgttttgccc atattcggaa
    13321 taggattcaa ggtaggccgt ctggatctct ttgccgataa actcggcata tttcgggatc
    13381 agataacctt tcaggaactc cagatagcgt tctgcctgct cttgtgggaa ctgctcgcgc
    13441 tcaatctgct gttccaggac gtagaacaga tggaccgggt ttgctgccac ttctacatga
    13501 tcgaagttga acacgcggga gaggatctta aacgcaaaac gcgtcgacag accgttcatc
    13561 ccttcatcga caccggcgta gtcacgatat tcctgatacg acttggcttt gggatcggtg
    13621 tctttcagac tttcgccatc ataaacccgc atctttgaat aaatgctgga gttttctggc
    13681 tctttcaggc gcgaaagaat ggaaaaacgt gacagtgttt cgagcgtgcc aggggcgcat
    13741 ggggcgtgag tcaattcact gtgattaagc aatttctcgt agattttgat ctcttcggaa
    13801 atgcgcaagc aatacggcac cttcacgatg taaacacgat cgaggaaggc ttcgttgttt
    13861 ttgttattac ggaaagtgac ccattcggac tcgttcgagt gtgcgagaat aatcccgttg
    13921 aacggcaggg cggagatacc ttccgtcccg ttgtagttac cttcctgagt ggcggttaac
    13981 aagggatgca gtactttaat cggtgcttta aacatctcaa cgaattccat gatcccctga
    14041 ttggcgcggc acagcgcacc ggaatagccg taggcgtccg ggtcattctg cgcgtagtgt
    14101 tcgagtttac gaatatcgac tttcccaacc agcgcggaga tgtcctggtt gttctcatcg
    14161 ccgggttccg ttttggcgat agcaatttgt tgcagaattg acggccagac cttcactacc
    14221 cggaacttag tgatatcgcc accaaattca tgcaggcgtt ttgccgccca cggcgacatg
    14281 atggtgccga gataacggcg aggaatgcca tactcttttt ccagaatctg cgcatcttcc
    14341 tgcggattga aaagacagaa cggatgatcg ttgaccgggc tacgctcacc gttcgcgctc
    14401 aatacataaa tcggtacgag ctgcattaat gatttcagtc gctcagcaag cgatgattta
    14461 cccccaccca caggccccag cagatacagg atttgtttct tctcttccag cccctgagcc
    14521 gcgtgtttca gataagagac aatctgttca atcgcgtctt ccatgccgta aaactcttca
    14581 aacgccggat aacgtgcaat gacccggtta gaaaagagtc gagaaagtct gggttcctgg
    14641 gctgtatcga ccatgacagg ctcaccgata gccatcaata gccgctcagc cgcgttggca
    14701 taagcactgc gatcttgccg acaagtggta agaaactcct gcagtgtgaa ctcttcgtcc
    14761 ttggcagctt catatcgctg gcgatagtga tcgaatatat tcatggtatg ccgtcctttc
    14821 gttttttagc acaggttaag agccgttcat atgaatagta gaggctcccg gaagaggtaa
    14881 actgaacgac gtctcttgct aaaacacagc aactctcatg ccattttatc gacgatgaga
    14941 acaacgtgcc cggtgataca ccttcaaaat taagcgtaga tggcaaatgg aaaacttgcc
    15001 tgcacggctt tcttaatttc aatggcatat caacaactca tccataaatt ttgcataatt
    15061 aatgtaaaga ccaggctcgc cagtaacgct aaattcattt ggctgtaagc gcggtgtcat
    15121 ccgcgtcagg aaaattaaac agttacttta aaaaatgaaa acgtaaaaag gttgggtttc
    15181 gatgtattga cgggtaaact ttgtcgcccg ctaaacattt gtttaaggaa tgattaattg
    15241 tgaccaaact caaacttctg gcacttggag tgcttatcgc aacgtctgca ggcgtagcgc
    15301 acgctgaagg taaattttcc ctgggcgcag gcgtaggtgt cgttgaacac ccatataaag
    15361 attacgatac cgatgtttac ccagtaccgg taatcaacta tgaaggcgat aacttctggt
    15421 tccgtggctt aggtggtggt tactacctgt ggaatgacgc aacggataaa ctttcaatta
    15481 ccgcttactg gtcgccgctt tacttcaaag cgaaagacag tggcgatcac caaatgcgtc
    15541 acctggatga ccgtaagagc accatgatgg ctggtctgtc ttatgctcac tttacccagt
    15601 acggttacct gcgtaccacc ctggctggcg ataccctgga taacagcaac ggcatcgtct
    15661 gggatatggc ctggttgtat cgttacacca acggtggcct gaccgtgact ccgggtattg
    15721 gtgtgcagtg gaacagcgaa aaccagaacg aatactatta tggcgtatcg cgcaaagagt
    15781 ccgctcgcag cggtctgcgt ggctataacc cgaacgacag ctggagccct tacctggagc
    15841 tgagcgccag ctacaacttc ctcggcgact ggagtgttta cggtaccgca cgctacaccc
    15901 gtctgtctga tgaagttact gacagcccga tggtggataa atcctggact ggcctgattt
    15961 ctaccgggat cacctacaaa ttctgataat gcatctttcc agggcatttt gtgcataaaa
    16021 acagggcgtc acgccctgtt ttgcattacg gtggtgcaat acctgggagg aaacaatgca
    16081 acaaaaaatg attcaattta gtggcgatgt ctcactgcca gccgtagggc agggaacatg
    16141 gtatatgggc gaagatgcca gtcagcgcaa aacagaagtt gctgcactac gcgcgggcat
    16201 tgaactcggt ttaaccctca ttgataccgc cgaaatgtat gccgatggcg gtgccgaaaa
    16261 ggtggttggg gaagcattaa ccggtctgcg agagaaggtc tttctcgtct ctaaagtcta
    16321 tccgtggaat gctggcgggc aaaaagcgat aaatgcatgc gaagccagtt tacgccgtct
    16381 caatactgat tatctcgatc tttacttatt acactggtct ggcagtttcg cttttgaaga
    16441 gactgtcgca gcgatggaaa aattgatcgc ccagggaaaa atccgccgct ggggcgtttc
    16501 taaccttgat tatgctgata tgcaggaact ctggcagctg ccggggggaa atcagtgtgc
    16561 cactaatcag gtgctttacc atctcggttc acgaggaatt gagtacgatc tactcccctg
    16621 gtgccagcaa cagcagatgc cggtgatggc ttacagtccg ttagcccagg ccgggcggtt
    16681 gcgcaatgga ctgttaaaaa acgcggtagt caacgaaatt gcacatgctc acaatatcag
    16741 cgcggcacaa gtattgttgg cgtgggtgat cagtcatcag ggtgtgatgg cgattccaaa
    16801 agcggccacg attgcccatg tccaacaaaa tgcggctgtg cttgaggtcg aactttcttc
    16861 agcggaatta gctatgctgg ataaggcata tccggcacca aaaggaaaaa ctgcgctgga
    16921 tatggtgtga tgttgtgtgc cggatgcatt gcacccggca cacaacatta acgtaaatta
    16981 acgtttcgca acgcgaatgg attgcgccag atgtgcaggt ttctctttgg tcactttttg
    17041 cgtttctgaa gcgtaagccg tttctacaca aacaaatgtt ttgtagccat catccggcat
    17101 atcgcccatg ctaattgaaa gcgccggtcc cgggttccag ccgacaacgt tcagatgatg
    17161 ctggtggcct acggcgataa tacgattcag cgcttcatca ttaatcacgc tgcaatcttg
    17221 tggattcaga tacacgcgat cggtacggtc agggaaggtc tgaataccat cggtcagtac
    17281 attttctttc gcgtcattca ctttatcaat gaagcgatcg cccagcccac tgacgcttac
    17341 cttagcgata tcacccacgt taaagtaggt atgcagggca gaggtggttt caaattcgcc
    17401 atgtgattca agatcgattt cacaagtttt acccacgcgg aaatgcgcta acagcgtaaa
    17461 gtcgtgcggc cagaattttt tcgtctcttc gctttgcgtc aattcaaaag tcagcgctac
    17521 gccatcagca tcttcatgat gtgatttcag cgtccacggc aggttgcggg caaaaccgtg
    17581 cgcaggcaga ccttgttgtg ccgccggacc aaaccacggc cagcaaaccg gtacgccacc
    17641 gcgaatagcg acgccatttt tgaacggtgt gttgttgctc aaccacagaa cttcttcttc
    17701 acccgcaggt ttccacgaga gaaggtgtgc gccctgtaat gcaaaagagg cttttacctg
    17761 gggatgatcg accacaatga ggtccagttc atccagttta cgacgggaga ggacagggga
    17821 gatttgttcg atgaccggaa gggcaaaaat tttcttaatc atgacgcagt cctttaactt
    17881 cattttatca ggtaaaaaaa agagcgaccg aagtcgctct ttttagatca cagtgtcatc
    17941 tcaacttatt tggagatgtg agcgatcagg tccagaactt tgttggagta accggtttcg
    18001 ttgtcgtacc aggataccag tttcacgaag ttgtcgttca gagcgatacc agctttagca
    18061 tcgaacacgg aagtgcaaac ttcgccgttg aaatcggtag atactacgtc atcttcggtg
    18121 tagcccagaa cgcctttcat ttcgccttca gcagcagctt taacggcagc tttgatctgc
    18181 tcgtaagttg cagctttttc cagacgaacg gtcaggtcaa ctacagatac gttcggggtc
    18241 ggaacgcgga acgccatacc agtcagtttg ccattcagtt ctggcagtac tttacctaca
    18301 gctttagcag caccggtaga ggacgggatg atgttctggg aagcgccgcg gccgccgcgc
    18361 cagtctttgt gagacgggcc atcaacggtt ttctgagtag cggtagtagc gtgaacggtg
    18421 gtcatcagac cttcgatgat gccgaagtta tcgttgataa ctttagccag cggagccagg
    18481 cagttggtgg tgcaggaagc gttggaaacg atgtcctggc cagcatattt gtcgaagtta
    18541 gcgcctttaa cgaacatcgg agtgttgtct ttagacggac cagtcataac cactttcttc
    18601 gcaccagcgg tgatgtgttt acgagcagtt tcgtcagtca ggaacagacc agttgcttca
    18661 gcgacaacgt caacaccaac ttcgtcccat ttcaggttag ccggatcacg ttcagcggta
    18721 acacggattt ttttaccgtt aacgatcaga tgaccgtctt tcacttcaac ggtaccgtcg
    18781 aaacggccgt gagtggagtc atatttcagc atgtatgcca tgtaatcagc gtctaacagg
    18841 tcgttgattg caacgatctc gatgtcagaa cgtttctgag cagcacggaa aacaatgcga
    18901 ccgatacggc caaaaccgtt gatacctact ttgatagtca tatattccac cagctatttg
    18961 ttagtgaata aaaggttgcc tgtaaaatta caaaaacctt acgcagcgtc aagcggaatc
    19021 gtgtcaatca ttgcgacaaa tcaatcctgt gcctaagcat tacgcgactg actcgcctca
    19081 ctcttccttt gggcttgaga ccacatgggg tcggcgcccc gaattttaaa gggcaattac
    19141 gataaaaatg tgattttcat cacgatttag gtgcagccat ttcgtcgaga tcaagtttag
    19201 gacaaaattt tgccagttgg tgttaatgtt ttgttagaat cagtcacgta atgtgagcac
    19261 gattaaagtg agatgtgagc aaatggctaa taaaccttcg gcagaagaac tgaaaaaaaa
    19321 tttgtccgag atgcagtttt acgtgacgca gaatcatggg acagagccgc catttacggg
    19381 tcgtttactg cataacaagc gtgacggcgt atatcactgt ttgatctgcg atgccccgct
    19441 gtttcattcc caaaccaagt atgattccgg ctgtggctgg cccagtttct acgaaccggt
    19501 aagtgaagaa tccattcgtt atatcaaaga cttgtcacat ggaatgcagc gcatagaaat
    19561 tcgttgcggt aactgtgatg cccatctggg gcatgtcttc cccgacgggc cgcagccaac
    19621 gggcgaacgt tattgtgtta actctgcctc tttacgcttt accgatggcg aaaacggcga
    19681 agaaatcaac ggttgaaaaa acgattcagc aacttattcc acaggagcgg aaaaattatg
    19741 aatcttgatg acattatcaa cagcatgatg cctgaggtat accagcgttt gtcgaccgcc
    19801 gttgaactgg ggaaatggcc tgatggcgtt gcgttgaccg aggaacaaaa agagaactgc
    19861 ctgcaactgg tgatgctgtg gcaagcccgc cataatatcg aagcacagca tatgacaatt
    19921 gacacaaatg gtcagatggt catgaagagc aaacagcagt taaaagaaga ttttggtatc
    19981 tcagcaaagc ctattgccat gtttaagtaa gtggttcatc ccctttttgc ctcggctatg
    20041 aaggggatag ccaacaatga ccccacgact catctcaatt atctcgccat gacctggcta
    20101 agtcccagtc cgatctcttg ccgtcccgtt cacacctgaa tgacttctcc tgaacttaag
    20161 tctcagacct atttggccgg taatccctct cgaatttgct ctttttgcgc cccgccttcc
    20221 atcaacctgt aacagaccca gccattttct gcgtaattgt gatctgagtt gtaaaacgca
    20281 gatcattatc tgtgttttac agatttaatg ttgacctcaa aaatcatgtg ggtaagtatg
    20341 atggccatct aagcaaaact aaacacagag gatgacgcaa tgaaagcact ggctcggttt
    20401 ggcaaggcct ttggcggcta caagatgatt gatgtcccac aacccatgtg tggcccggaa
    20461 gatgtagtga ttgaaattaa agccgcggca atctgcggcg cagacatgaa gcactacaat
    20521 gtcgatagcg gttctgatga gtttaactct atccgcggcc atgagttcgc aggttgtatt
    20581 gcgcaggttg gtgaaaaagt caaagactgg aaagtggggc aacgcgtcgt atcggataac
    20641 agcggtcacg tttgcggtgt ttgtccggcc tgtgaacaag gtgattttct gtgttgtaca
    20701 gaaaaagtaa accttggtct ggataataat acctggggcg gtggtttttc caaatattgt
    20761 ctggttcctg gtgaaattct caaaattcat cgtcatgcgt tgtgggaaat ccctgatggt
    20821 gttgattatg aggacgcagc cgtacttgac cctatctgta atgcctacaa atccatcgcg
    20881 cagcaatcga aattccttcc tggtcaggat gtggtcgtca tcggcactgg cccactcggg
    20941 ctgttctccg tacaaatggc gcgaattatg ggggcggtaa atatcgtcgt cgttggtctg
    21001 caagaagatg tggcggtccg cttcccggtt gcaaaagaac tgggtgcgac ggcagtagta
    21061 aatggttcta ccgaagatgt ggtggcgcgc tgccagcaaa tttgtggcaa agacaatctg
    21121 ggactggtga ttgaatgctc cggtgccaat atcgcactga aacaagccat cgaaatgctc
    21181 cgcccgaacg gggaagtggt acgcgttgga atgggcttca aacctcttga tttctcgatt
    21241 aatgacatta ccgcctggaa caaaagcatc attgggcata tggcctatga ctccacctca
    21301 tggcgtaacg ctatcaggct attagccagc ggcgctatca aagtcaaacc gatgatcacg
    21361 catcgtatcg gcctgtcgca atggcgcgaa gggtttgatg cgatggtcga taaaaccgca
    21421 atcaaagtga tcatgactta cgactttgat gaataaccac tctcctgaag gaacgttatc
    21481 gcatggaaca gataacaaaa ccgcattgtg gtgcacggct ggatcgctta ccggattgcc
    21541 gctggcattc atcaatgttt gccatcgtcg cgtttggctt gcttgtctgc tggagtaatg
    21601 ccgttggtgg cttgatcctc gcgcagctga aagcgttggg ctggacagat aattccacca
    21661 cagccacatt ctcagcaatc acgaccgccg gaatgtttct cggtgcgctg gtgggcggca
    21721 tcattggcga caaaaccggt cgcagaaatg cgttcatcct ctatgaggcc attcatattg
    21781 cctcgatggt tgtcggtgct ttctcaccga atatggattt ccttattgcc tgccgttttg
    21841 tgatgggagt tgggctggga gctttactgg ttacgctgtt tgctggtttc accgaatata
    21901 tgcccggtag aaatcgtgga acgtggtcaa gtcgggtttc ctttattggc aactggtcat
    21961 atccgctctg ttcattgata gcgatgggac tcacgccgct gattagtgca gagtggaact
    22021 ggcgggtaca actgcttatc cctgcaatat tgtcgcttat cgctacggcg ctggcctggc
    22081 gctactttcc tgaatccccg cgctggctgg aatcgcgcgg acggtatcag gaagccgaga
    22141 aagtcatgcg gagtatagaa gaaggcgtca tacgccagac gggtaaacct ttgccgcctg
    22201 tggttattgc tgatgacggt aaagcgccac aagcggtgcc gtattcagcc ttactgacag
    22261 gagtattact gaaacgcgtg atattaggct cttgtgtgct gattgccatg aacgttgtgc
    22321 agtacacact aattaactgg ttgccaacaa tattcatgac ccaggggatt aatttaaaag
    22381 actcgattgt tttaaatacc atgagtatgt ttggcgcgcc atttggtatt tttattgcca
    22441 tgctggtgat ggataaaatt ccgcgtaaaa caatgggtgt ggggctatta atcctgattg
    22501 cggtgctcgg atatatctat tcactgcaaa ccagtatgtt gctcataacg ttgattggtt
    22561 tcttcctgat tactttcgtc tatatgtacg tttgctatgc ctcggcagtg tatgtccctg
    22621 aaatctggcc gacagaggcc aaactccgtg gctccggtct ggcgaatgcg gtagggcgaa
    22681 tcagtggtat tgccgcacct tatgccgttg cagtgctgct cagtagttat ggcgttacgg
    22741 gagtctttat tcttctgggg gcggtttcaa ttattgtcgc aattgctatc gccaccattg
    22801 gaatcgaaac caaaggtgtc tccgttgaaa gtttaagtat tgatgcagta gccaataaat
    22861 aatacgggtg gattcaaaat gaaaaattca aaagcaatat tgcaggtgcc gggcacaatg
    22921 aaaattattt c
//
LOCUS       DACAOP010000075        22670 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.075, whole genome shotgun sequence.
ACCESSION   DACAOP010000075 DACAOP010000000
VERSION     DACAOP010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22670
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.075"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..531
                     /gene="tnpB"
                     /locus_tag="IT892_003146"
     CDS             <1..531
                     /gene="tnpB"
                     /locus_tag="IT892_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAP3136334.1"
                     /translation="NWQKQKRKIQRLHSCIANIRRDYLHKVTTAVSKNHAMIVIEDLK
                     VSNMSKSAAGTVSQPGRNVRAKSGLNRSILDQGWYEMRRQLAYKQLWRGGQVLAVPPA
                     YTSQRCAYCGHTAKENRLSQSKFRCQVCGYTANADVNGARNILAAGHAVLACGEMVQS
                     GRPLKQEPTEMIQATA"
     gene            complement(571..1785)
                     /gene="ydcO"
                     /locus_tag="IT892_003147"
     CDS             complement(571..1785)
                     /gene="ydcO"
                     /locus_tag="IT892_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BenE family transporter YdcO"
                     /protein_id="HAP3136335.1"
                     /translation="MLRCLYAITHEVTMRLFSIPPPTLLAGFLAVLIGYASSAAIIWQ
                     AAIVAGATTAQISGWMTALGLAMGVSTLTLTLWYRVPVLTAWSTPGAALLVTGLQGLT
                     LNEAIGVFIVTNALIVLCGITGLFARLMRIIPHSLAAAMLAGILLRFGLQAFASLDGQ
                     FTLCGSMLLVWLATKAVAPRYAVIAAMIIGIVIVIAQGDVVTTDVVFKPVLPTYITPD
                     FSFAHSLSVALPLFLVTMASQNAPGIAAMKAAGYSAPVSPLIVFTGLLALVFSPFGVY
                     SVGIAAITAAICQSPEAHPDKDQRWLAAAVAGIFYLLAGLFGSAITGMMAALPVSWIQ
                     MLAGLALLSTIGGSLYQALHNERERDAAVVAFLVTASGLTLVGIGSAFWGLIAGGVCY
                     VVLNLIADRNRY"
     gene            1838..2374
                     /locus_tag="IT892_003148"
     CDS             1838..2374
                     /locus_tag="IT892_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP3136336.1"
                     /translation="MENLARFLSTTLKQLRQQRGWSLSRLAEATGVSKAMLGQIERNE
                     SSPTVATLWKIATGLNVPFSTFISPPQSATPSVYDPQQQAMVITSLFPYDPQLCFEHF
                     SIQMASGAISESTPHEKGVIEHVVVIDGQLDLCVDGEWQTLNCGEGVRFAADVTHIYR
                     NGGEQTVHFHSLIHYPRS"
     gene            2447..4408
                     /gene="rlhA"
                     /locus_tag="IT892_003149"
     CDS             2447..4408
                     /gene="rlhA"
                     /locus_tag="IT892_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA 5-hydroxycytidine C2501 synthase"
                     /protein_id="HAP3136337.1"
                     /translation="MTVSSHRLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNA
                     SNSLKDIAELVPFAHRYGAKIFVTLNTILHDDELEPAQRLITDLYQTGVDALIVQDMG
                     ILELDIPPIELHASTQCDIRTVEKAKFLSDVGFTQIVLARELNLDQIRAIHQATDATI
                     EFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLS
                     MKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEERGDLARAS
                     SGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVVKVAKDHLDV
                     AVTEPLANGDGLNVLIKREVVGFRANTVEKTGENQYRVWPNEMPADLHKIRPHHPLNR
                     NLDHNWQQALTKTSSERRVAVDIELGGWQEQLILTLTSEEGVSITHTLDGQFDEANNA
                     EKAMNNLKDGLAKLGQTLYYARDVQINLPGALFVPNSLLNQFRREAADMLDAARLASY
                     QRGSRKPVADPAPVYPQTHLSFLANVYNQKAREFYHRYGVQLIDAAYEAHEEKGEVPV
                     MITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVNGDEVLTLKFDCRPCEMHVIGKIKN
                     HILKMPLPGSVVASVSPDELLKTLPKRKG"
     gene            complement(4500..4730)
                     /locus_tag="IT892_003150"
     CDS             complement(4500..4730)
                     /locus_tag="IT892_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncJ family protein"
                     /protein_id="HAP3136338.1"
                     /translation="MFTKALSVVLLTCALFSGQLMAGHKGHEFVWVKNVDHQLRHEAD
                     SDELRAVAEESAEGLREHFYWQKSRKPEAGQR"
     gene            4952..5128
                     /gene="hicA"
                     /locus_tag="IT892_003151"
     CDS             4952..5128
                     /gene="hicA"
                     /locus_tag="IT892_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415954.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin HicA"
                     /protein_id="HAP3136339.1"
                     /translation="MKQSEFRRWLESQGVDVANSSNHLKLRFHGRRSVMPRHPCDEIK
                     EPLRKAILKQLGLS"
     gene            5174..5590
                     /gene="hicB"
                     /locus_tag="IT892_003152"
     CDS             5174..5590
                     /gene="hicB"
                     /locus_tag="IT892_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HicB"
                     /protein_id="HAP3136340.1"
                     /translation="MRYPVTLTPAPEGGYMVSFVDIPEALTQGETVAEAMEAAKDALL
                     TAFDFYFEDNELIPLPSPLNSHDHFIEVPLSVASKVLLLNAFLQSEITQQELARRIGK
                     PKQEITRLFNLHHATKIDAVQLAAKALGKELSLVMV"
     gene            5669..7075
                     /locus_tag="IT892_003153"
     CDS             5669..7075
                     /locus_tag="IT892_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP3136341.1"
                     /translation="MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVS
                     HAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRD
                     PSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
                     QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSV
                     ATDVKEGIDLQALELALQEYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTL
                     IEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQR
                     LQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKI
                     HHNDSGYFLWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWG
                     EREEQAVKQLGKLIQERL"
     gene            7320..8465
                     /locus_tag="IT892_003154"
     CDS             7320..8465
                     /locus_tag="IT892_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP3136342.1"
                     /translation="MSKTFARSSLCALSMTIMTAHAAEPPTNLDKPEGRLDIIAWPGY
                     IERGQTDKQYDWVTQFEKETGCAVNVKTAATSDEMVSLMTKGGYDLVTASGDASLRLI
                     MGKRVQPINTALIPNWKTLDPRVVKGDWFNVGGKVYGTPYQWGPNLLMYNTKTFPTPP
                     DSWQVVFVEQNLPDGKSNKGRVQAYDGPIYIADAALFVKATQPQLGISDPYQLTEEQY
                     QAVLKVLRAQHSLIHRYWHDTTVQMSDFKNEGVVASSAWPYQANALKAEGQPVATVFP
                     KEGVTGWADTTMLHSEAKHPVCAYKWMNWSLTPKVQGDVAAWFGSLPVVPEGCKASPL
                     LGEKGCETNGFNYFDKIAFWKTPIAEGGKFVPYSRWTQDYIAIMGGR"
     gene            8483..9496
                     /locus_tag="IT892_003155"
     CDS             8483..9496
                     /locus_tag="IT892_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP3136343.1"
                     /translation="MTYAVEFDNVSRLYGDVRAVDGVSIAIKDGEFFSMLGPSGSGKT
                     TCLRLIAGFEQLSGGAISIFGKPASNLPPWERDVNTVFQDYALFPHMSILDNVAYGLM
                     VKGVNKKQRHAMAQEALEKVALGFVHQRKPSQLSGGQRQRVAIARALVNEPRVLLLDE
                     PLGALDLKLREQMQLELKKLQQSLGITFIFVTHDQGEALSMSDRVAVFNNGRIEQVDS
                     PRDLYMRPRTPFVAGFVGTSNVFDGLMAEKLCGMTGSFALRPEHIRLNTPGELQANGT
                     IQAVQYQGAATRFELKLNGGEKLLVSQANMTGEELPATLTPGQQVMVSWSRDVMVPLV
                     EER"
     gene            9497..10438
                     /locus_tag="IT892_003156"
     CDS             9497..10438
                     /locus_tag="IT892_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3136344.1"
                     /translation="MAMNVLQSPSRPGLGKVSGFFWHNPGLGLFLLLLGPLMWFGIVY
                     FGSLLTLLWQGFYTFDDFTMSVTPELTLANIRALFNPANYDIILRTLTMAVAVTIASA
                     ILAFPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVAQWFLQHL
                     GLEPLLTAFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQAS
                     ADLGARPRQTFRYVVLPLAIPGIAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQ
                     QGAIGNMPMAAAFTLVPIILIALYLAFVKRLGAFDAL"
     gene            10428..11222
                     /locus_tag="IT892_003157"
     CDS             10428..11222
                     /locus_tag="IT892_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3136345.1"
                     /translation="MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPP
                     QGLTLRWFSVAAQRSDILDAVTLSLKVAALATLIALVLGTLAAAALWRRDFFGKNAIS
                     LLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
                     WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTL
                     PLWLLNQLGRPRDVPVTNVVALLVMLVTTLPILGAWWLTREGDNGQ"
     gene            11244..12668
                     /gene="patD"
                     /locus_tag="IT892_003158"
     CDS             11244..12668
                     /gene="patD"
                     /locus_tag="IT892_003158"
                     /EC_number="1.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminobutyraldehyde dehydrogenase"
                     /protein_id="HAP3136346.1"
                     /translation="MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAA
                     VRAADAAFAEWGQTTPKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIP
                     AIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLA
                     PALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINILFGRGKTVGDPLTGHPKVR
                     MVSLTGSIATGEHIISHTASSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNA
                     GQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVSKA
                     VEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNE
                     EQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLS
                     GYGKDMSLYGLEDYTVVRHVMVKH"
     gene            complement(12765..12860)
                     /gene="yncL"
                     /locus_tag="IT892_003159"
     CDS             complement(12765..12860)
                     /gene="yncL"
                     /locus_tag="IT892_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response membrane protein YncL"
                     /protein_id="HAP3136347.1"
                     /translation="MNVSSRTVVLINFFAAVGLFTLISMRFGWFI"
     gene            13055..13228
                     /locus_tag="IT892_003160"
     CDS             13055..13228
                     /locus_tag="IT892_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GhoT/OrtT family toxin"
                     /protein_id="HAP3136348.1"
                     /translation="MSLYQHMLVFYAVMAAIAFLITWFLSHDKKRIRFLSAFLVGATW
                     PMSFPVALLFSLF"
     gene            13314..13547
                     /locus_tag="IT892_003161"
     CDS             13314..13547
                     /locus_tag="IT892_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcY family protein"
                     /protein_id="HAP3136349.1"
                     /translation="MSHLDEVIARVDAAIEESVIAHMNELLIALSDDAELSREDRYTQ
                     QQRLRTAIAHHGRKHKEDMEARHEQLTKGGTIL"
     gene            complement(13548..13997)
                     /locus_tag="IT892_003162"
     CDS             complement(13548..13997)
                     /locus_tag="IT892_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HAP3136350.1"
                     /translation="MNQSLTLAFLIAAGIGLVVQNTLMVRITQTSSTILIAMLLNSLV
                     GIVLFVSILWFKQGMAGFGELVSSVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAV
                     LVASQLIGGLMLDIFRSHGVPLRALFGPICGAILLVVGAWLVARRSF"
     gene            complement(13994..14512)
                     /gene="mddA"
                     /locus_tag="IT892_003163"
     CDS             complement(13994..14512)
                     /gene="mddA"
                     /locus_tag="IT892_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine sulfoximine/L-methionine sulfone
                     acetyltransferase"
                     /protein_id="HAP3136351.1"
                     /translation="MSIRFARKADCAAIAEIYNHAVLYTAAIWNDQTVDADNRIAWFE
                     ARTLAGYPVLVSEENGVVTGYASFGDWRSFDGFRHTVEHSVYVHPDHQGKGLGRKLLS
                     RLIDEARDCGKHVMVAGIESQNQASLHLHQSLGFVVTAQMPQVGTKFGRWLDLTFMQL
                     QLDERTEPDAIG"
     gene            14693..15730
                     /gene="curA"
                     /locus_tag="IT892_003164"
     CDS             14693..15730
                     /gene="curA"
                     /locus_tag="IT892_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415966.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent curcumin/dihydrocurcumin
                     reductase"
                     /protein_id="HAP3136352.1"
                     /translation="MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLR
                     TVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVSRVVESNHPDYQSGDWVLGYSGW
                     QDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
                     PVGATVGQIGKLKGCRVVGVAGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKG
                     IDIYYENVGGKVFDAVLPLLNTSARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKR
                     IRLQGFIIAQDYGHRIHEFQREMGQWVKEDKIHYREEITDGLENAPQTFIGLLKGKNF
                     GKVVIRVAGDD"
     gene            15928..16593
                     /locus_tag="IT892_003165"
     CDS             15928..16593
                     /locus_tag="IT892_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415967.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP3136353.1"
                     /translation="MPGTGKMKHVSLTLQVENDLKHQLSIGALKPGARLITKNLAEQL
                     GMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKRQLDEINRIRYELELMAVALAVE
                     NLTPQDLAELQELLEKLQQAQEKGDMEQIINVNRLFRLAIYHRSNMPILCEMIEQLWV
                     RMGPGLHYLYEAINPAELREHIENYHLLLAALKAKDKEGCRHCLAEIMQQNIAILYQQ
                     YYR"
     gene            complement(16629..18731)
                     /locus_tag="IT892_003166"
     CDS             complement(16629..18731)
                     /locus_tag="IT892_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HAP3136354.1"
                     /translation="MKIFSVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVVSELDTP
                     AAVSVVDGEEMRLATPRINLSESLTGVPGLQVQNRQNYAQDLQLSIRGFGSRSTYGIR
                     GIRLYVDGIPATMPDGQGQTSNIDLSSVQNVKVLRGPFSALYGNASGGVMNVTTQTGQ
                     QPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVSTTRFTTHGYRDHSGAQK
                     NLANAKLGVRIDEASKLSLIFNSVDIKADDPGGLTKAEWKANPQQAPRAEQYDTRKTI
                     KQTQAGLRYERSLSSRDDMSVMMYAGERETTQYQSIPMAPQLNPSHAGGVITLQRHYQ
                     GIDSRWTHRGELGVPVTFTTGLNYENMSENRKGYNNFRLNSGMPEYGQKGELRRDERN
                     LMWNIDPYLQTQWQLSEKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPA
                     GSLKYAMTDAWNIYLAAGRGFETPTINELSYRADGQSGMNLGLKPSTNDTIEIGSKTR
                     IGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAGDFRVNA
                     SWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYVPEDGWYAGTEARYMGDIMA
                     DDENTAKAPSYTLVGLFTGYKYNCHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYE
                     PSPGRNYGVGMNIAWRFE"
     gene            18973..20034
                     /locus_tag="IT892_003167"
     CDS             18973..20034
                     /locus_tag="IT892_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HAP3136355.1"
                     /translation="MHLRHLFSSRLRGSLLLGSLLVVSSFSTQAAEEMLRKAVGKGAY
                     EMAYSQQENALWLATSQSRKLDKGGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQT
                     LWFGNTVNSAVTAIDAKTGEVKGRLVLDDRKRTEEVRPLQPRELVADDATNTVYISGI
                     GKESVIWVVDGGNIKLKTAIQNTGKMSTGLALDSEGKRLYTTNADGELITIDTADNKI
                     LSRKKLLDDGKEHFFINISLDTARQRAFITDSKAAEVLVVDTRNGNILAKVAAPESLA
                     VLFNPARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVSVKQ
                     KSTKQQEATQPDDVIRIAL"
     gene            complement(20147..21646)
                     /gene="ansP"
                     /locus_tag="IT892_003168"
     CDS             complement(20147..21646)
                     /gene="ansP"
                     /locus_tag="IT892_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparagine permease"
                     /protein_id="HAP3136356.1"
                     /translation="MSKHDTDTSDQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAI
                     GTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFL
                     GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNM
                     IGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTTGFHLITDNGGFFPHG
                     LLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLV
                     MLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMA
                     MGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIAS
                     WAFIIVCQMRLRKAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYT
                     IAALPIIGILLVIGWFGVRKRVAEIHSTAPVVEEDEEKQEIVFKPETAS"
     gene            21913..22530
                     /locus_tag="IT892_003169"
     CDS             21913..22530
                     /locus_tag="IT892_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HAP3136357.1"
                     /translation="MIKVYGVPGWGSTISELMLTLADIPYQFVDVSGFDHEGASRELL
                     KTLNPLCQVPTLALENDEIMTETAAIALMVLDRRPDLAPPVGRAERQLFQRLLVWLVA
                     NVYPTFTFADYPERWAPDAPEQLKKNVIEYRKSLYIWLNSQLTAEPYAFGEQLTLVDC
                     YLCTMRTWGPGHEWFQDNATNISAIADAVCQLPKLQEVLKRNEII"
BASE COUNT         5776 a         5574 c         5834 g         5486 t
ORIGIN      
        1 aactggcaaa agcagaaacg caaaatacag cgactgcatt cctgtatcgc aaatatccgc
       61 agggactacc ttcacaaagt cacaacggcc gtcagcaaaa accacgcaat gatagtcatt
      121 gaggatttga aggtcagcaa catgtcaaag tcagcagcgg gtacggtcag ccagccgggg
      181 cgcaatgtcc gggcaaaatc aggtttaaac cgttcgatac tggatcaggg ctggtatgaa
      241 atgcgccgcc agcttgcgta caagcagctc tggcgtggcg gtcaggtgct tgctgttccg
      301 ccagcgtata caagccagcg ttgcgcgtac tgtggtcata cagcgaaaga gaaccgcctg
      361 tcacaaagta aattcagatg ccaggtatgt ggatatacag cgaacgccga tgtaaatggc
      421 gctcgcaaca ttttagcggc ggggcacgcc gttcttgcct gtggagagat ggtgcagtca
      481 ggccgcccgt tgaagcagga acccaccgaa atgattcagg cgacagcctg aacgtagcag
      541 ggatccacgt ccttcagggc gtggaggatg tcaatatcgg tttctgtcag cgattaaatt
      601 caacaccacg taacaaacgc ctccggcaat taatccccaa aacgcagaac caatcccgac
      661 cagcgtcaat ccacttgccg ttaccagaaa tgccaccacc gccgcgtctc gctcacgctc
      721 attatgcagc gcctgataca aactgccgcc gatggtactt aacagcgcca gacctgccag
      781 catctggatc caacttacgg gcagggcagc catcatcccg gtaatggcac taccaaacag
      841 acctgcgagc aaatagaaaa tgcctgcaac ggcagcggcc agccaacgtt gatctttatc
      901 cggatgcgct tccgggcttt ggcaaatagc cgcggtgatt gccgcaatac cgacggaata
      961 aacgccgaaa ggggaaaaaa ccagtgccag caatccagta aatacaatta atggcgaaac
     1021 aggagccgaa tatccagctg ctttcattgc tgcgataccc ggtgcgtttt gcgatgccat
     1081 cgtcaccaga aaaaggggga gtgcaacgct caggctgtga gcaaacgaaa aatcaggggt
     1141 aatataagtg gggagaacgg gtttaaagac aacatcagtt gtgacaacgt caccttgcgc
     1201 gatgacgatc acgatcccaa taatcatcgc ggcaattacc gcatagcgcg gcgcaacggc
     1261 cttggttgcc agccatacca gcaacatact tccacacaac gtaaattgac cgtccagact
     1321 ggcaaacgcc tgtaaaccaa agcgtaataa aatcccggca agcattgccg ccgcaagcga
     1381 gtgcggaata atgcgcatca gacgagcaaa gagtcccgtt atgccgcaga ggactattag
     1441 cgcgttggtg acaataaaaa cgccgatggc ttcgttaagt gttagtccct gcaatccggt
     1501 gaccaacaaa gccgcgccag gcgttgacca tgcggtgaga acaggtacgc gataccataa
     1561 tgtcagagtc agcgtactga cgcccattgc cagccccagc gccgtcatcc agccagagat
     1621 ttgtgcagtg gtggctccgg cgacaatcgc tgcttgccag attattgccg ctgaactggc
     1681 gtagccaatt aataccgcca gaaaccccgc cagtagcgtg ggtggaggaa tagaaaacag
     1741 acgcatagtc acctcgtgcg ttatagcgta caggcaccgt agcatttgtc cgttataacg
     1801 cacaagtgat aaacttccgt tttgccggag gagtcgcatg gaaaatctcg ctcgcttttt
     1861 atccaccaca cttaaacaac tacgccagca gcgcggctgg agtctttcgc gactggcaga
     1921 agcgacgggc gtttctaaag caatgttagg gcagattgag cgtaatgagt ccagtccgac
     1981 ggtcgcgaca ttatggaaaa ttgccaccgg gttgaacgta ccattttcaa catttatttc
     2041 tccgccgcag tccgctacgc cttcagttta tgatccacaa cagcaggcga tggtgatcac
     2101 ttcgctgttt ccttatgatc cacaactctg ctttgaacac ttctcgattc agatggcatc
     2161 tggtgcaata agcgaatcga cgccccatga gaagggggta atcgaacatg tcgtcgtcat
     2221 tgatggacaa cttgatctgt gcgttgatgg ggaatggcag acccttaatt gtggggaagg
     2281 cgttcgattt gctgcagacg tcacgcatat ctatcgtaat ggtggggagc aaaccgtaca
     2341 ttttcattcc ctcatccatt acccgcgcag ttaagcggga aaactatttc gcaacgtcgc
     2401 gcttgtggct aaaatagccg ccatttttca gctactggat aagaatgtga ccgtatcttc
     2461 tcatcgactt gaactgttaa gcccggcacg cgatgccgcc attgcccgcg aagctatttt
     2521 gcacggtgcc gatgctgttt atatcggcgg ccctggtttt ggtgcccgtc ataatgccag
     2581 taatagcttg aaagatattg ccgagctggt gccgtttgcc catcgttatg gtgcaaaaat
     2641 tttcgtcacg cttaacacca ttttgcatga tgatgagctg gaacccgcgc aacggctgat
     2701 tactgacctc taccagaccg gtgtcgatgc gctgattgtt caggatatgg ggattctgga
     2761 acttgatatt ccgccgattg aactgcacgc cagtacgcag tgcgacattc gtacagttga
     2821 aaaagcgaag ttcctctctg atgttggctt cacgcagatt gtgctggcgc gagagctgaa
     2881 tcttgatcag atccgcgcga ttcaccaggc tacggacgcg accattgaat tctttattca
     2941 tggggcactg tgcgtggcct attcgggtca gtgctacatt tctcatgcgc aaacagggcg
     3001 tagcgccaac cgtggcgatt gctcgcaggc gtgccgtttg ccatacacat tgaaagacga
     3061 tcaggggcgg gtggtttcct atgaaaaaca tctgctgtcg atgaaagata acgatcagac
     3121 tgccaacctc ggcgcgctga ttgatgctgg tgtacgctcc ttcaagattg aagggcgtta
     3181 caaagatatg agctacgtga agaatatcac cgcccattat cgccagatgc ttgatgccat
     3241 tattgaagaa cgtggcgatc tggcgcgcgc ttcatcaggt cgtactgaac atttctttgt
     3301 tccatcgacg gaaaagactt tccaccgtgg tagcacagat tattttgtga atgcccgtaa
     3361 aggcgatatt ggcgcgttcg attcgccgaa atttatcggc ctgccggtag gcgaagtagt
     3421 gaaagtggcg aaagatcatc tcgatgttgc cgttaccgag ccactggcaa atggcgatgg
     3481 cctgaacgtg ttgattaaac gtgaagtcgt cggttttcgt gccaatacgg tcgagaaaac
     3541 cggagaaaat cagtaccgcg tctggcccaa tgaaatgcca gcagatttgc acaaaattcg
     3601 tccacatcac ccactaaacc gtaatcttga tcataactgg cagcaggcac tgacaaaaac
     3661 ctccagcgaa cgtcgggtgg cggtagacat tgaactgggc ggctggcagg aacaactgat
     3721 tctgaccctc accagtgaag agggtgtcag catcacgcat acgctggacg ggcagttcga
     3781 cgaagccaat aacgccgaaa aagcaatgaa caatctgaag gatggtctgg caaaactggg
     3841 gcaaaccctc tattacgccc gcgatgtgca aattaatttg ccgggggcgc tgtttgtacc
     3901 aaacagtctg ttaaaccagt tccgccgtga agctgctgac atgctggatg ctgcgcgtct
     3961 tgccagttac cagcgcggca gccgtaaacc ggttgctgat cctgcgccgg tttatccgca
     4021 aacgcatctg agtttcctcg cgaacgtata caaccagaaa gcgcgtgaat tttatcatcg
     4081 ctatggtgtg cagctgattg acgcggcgta tgaagcacat gaagagaagg gcgaagtccc
     4141 ggtgatgatc accaagcatt gtctgcgctt tgcctttaat ctgtgcccga aacaggcgaa
     4201 aggcaatatc aaaagctgga aggcgacgcc aatgcaactg gttaacggcg atgaagtatt
     4261 aacgctaaag tttgattgcc gcccatgcga gatgcacgtc attggcaaaa tcaaaaatca
     4321 catactgaaa atgccgttac cgggaagcgt agtggcatcc gtaagtccgg atgagctgct
     4381 gaaaacattg ccgaagcgaa aagggtaaaa cgccagtttt ctggttactc acaacttatt
     4441 gaatctgcat gatattgcct gccgggtaag gcgttacgcc gcatccggca tcaaatgact
     4501 caacgttgtc ccgcttctgg tttgcgcgat ttttgccagt aaaaatgctc gcgcaaacct
     4561 tccgccgact cttccgccac agcacgcaat tcatcgctgt ccgcttcatg acgcagctga
     4621 tgatccacat tctttaccca cacaaattca tgtcctttgt gccctgccat gagttgtcct
     4681 gaaaacagag cacacgttaa taagacaacc gataacgcct tcgtaaacat cctgccacct
     4741 ttttcttacc ttttgccgct atgatgccga tcgtttcttg aggttattat tcagttttgc
     4801 aaattagcgc aaagaaattc tggaatcttc cttcctgatt ttgcattgca ttctgccgtt
     4861 gcggcgattt agtgctattt tcgagcaaat tacacacgga ggtaaacact aatgtttact
     4921 ttgttgatat actcagcggc agggaggcga tgtgaaacaa agcgagttca gacgttggct
     4981 cgaatctcag ggcgtcgatg tagcgaatag cagcaaccat ttgaaactca ggtttcatgg
     5041 gaggcgcagt gtcatgccgc gtcacccctg cgatgagatt aaagaaccat tgcgtaaagc
     5101 aatcctgaaa caactcggtt tgagttaatc gccaattaaa aaggttaatg acatgcgaga
     5161 gacagtcgaa attatgcgtt atcccgtcac tcttacaccc gcgccggaag gcggttatat
     5221 ggtttctttt gtggatatcc ctgaagcgtt gacccagggc gaaactgtcg ctgaagcgat
     5281 ggaagcggca aaagatgctt tactgaccgc atttgatttt tattttgaag ataacgagct
     5341 tatcccttta ccttcgccat taaatagtca cgatcacttt attgaagtac ctttgagcgt
     5401 cgcctctaag gtattgctgt taaatgcttt tttacagtca gaaatcactc agcaagagtt
     5461 agccaggcga attggcaaac ctaaacagga gattactcgc ctatttaact tgcatcatgc
     5521 gacaaaaatc gacgccgtcc agctcgcggc aaaggcgctt ggcaaagagt tatcgctggt
     5581 gatggtttaa ttacagttaa cgaaaagttg tcatttttaa caactgatat agactgccga
     5641 atcatctgca cataattacg attcgataat gaaaaaatac cagcagcttg cagaacaatt
     5701 acgcgagcag attgcgtcgg gtatctggca acccggcgat cgtttgcctt cgttgcgtga
     5761 ccaggtggcg ctttcaggca tgagctttat gactgtcagc catgcctatc agttgctcga
     5821 aagtcaggga tatattatcg cacgaccgca gtcgggttat tacgttgcgc cacaggcaat
     5881 aaaaatgccg aaagcgccag tcattccagt cactcgagat gaagcagtcg atatcaacac
     5941 ttatattttt gatatgttgc aggccagtcg cgatccgtcg gtcgttccgt ttgcctcggc
     6001 ctttcccgac ccgcgacttt tccccctcca acaactaaac cgctcgctgg cgcaggtaag
     6061 caaaaccgcc acagcgatga gcgtgattga aaacttaccg ccaggaaacg cagaactgcg
     6121 tcaggctatt gctcgtcgct atgccttaca gggcatcacc atttctcctg atgaaattgt
     6181 cattactgcc ggggcgttag aggcattaaa cctcagtttg caagcggtaa ctgaaccggg
     6241 cgattgggtg atagtagaga atccttgttt ctacggtgcg ttgcaggcgc tggagcggct
     6301 acggctgaag gcgttatcgg tggcgacgga tgttaaagaa gggatagatc ttcaggcgct
     6361 ggaactggcg ttgcaggagt atccggtgaa agcgtgctgg ctgatgacta atagccagaa
     6421 tccactcgga tttaccttaa cgccgcaaaa aaaagcacaa ctggtggcgt tgctcaatca
     6481 gtacaacgta acgctgattg aagatgacgt ttacagcgaa ctttattttg gacgggaaaa
     6541 accgctgcct gcgaaagcgt gggatcgcca cgatggcgtt ttgcattgct cttcgttttc
     6601 gaaatgtctg gtgcctggtt ttcgtattgg ttgggtcgcc gccggaaaac atgcacgtaa
     6661 aattcaacgc ttgcagttga tgagtacgct ttccaccagc tcaccgatgc aacttgcgct
     6721 ggtggattac ctttccacgc gccgatacga cgcccatctt cgtcgcctgc gtcgccagct
     6781 tgcggaacgt aaacaacgtg cctggcaggc actgctgcgt tatctgcctg cggaagtgaa
     6841 aattcatcat aatgacagtg gttactttct ctggttggag ctccccgagc cgttagatgc
     6901 cggcgaatta agcctggcgg cactgacgca tcatatcagt attgcgccgg gtaaaatgtt
     6961 ttctaccggt gaaaactggt cacgtttttt ccgttttaat accgcgtggc agtggggaga
     7021 gcgtgaagaa caggcggtaa aacaattagg caaacttatt caagaacggc tgtaatagcg
     7081 tttaatttaa ttcctcttag attgggtaat atgaatttcg aatagcagtc atatttccta
     7141 actccttgac tatactccag aagataacct tacagacggc ataatgcgcg gtagctcaca
     7201 acctgaataa attttctcag gggcgaaggt gtgcctgcaa gccgccgtct atggttaaac
     7261 aaggagatat ttttacggca cggcggctga acaattaatt acgacaggag taagacctta
     7321 tgagcaagac atttgcccgc agcagcctgt gtgcgctcag catgacaata atgaccgctc
     7381 acgccgccga accgcctacc aatttagata aaccggaagg gcgactggat attatcgcct
     7441 ggccgggata catcgaacgc ggacaaactg ataaacaata cgactgggta acgcagttcg
     7501 aaaaagagac aggctgcgcg gtgaatgtga aaaccgccgc gacttccgat gaaatggtca
     7561 gtctgatgac caaagggggt tacgatctgg ttacggcatc cggcgatgcc tcgctgcgtt
     7621 tgattatggg taaacgcgtg cagccgatta ataccgcatt gattcccaac tggaaaacgc
     7681 tcgatccgcg cgtggttaaa ggcgactggt ttaatgttgg cggcaaagtt tacggcacac
     7741 cttaccaatg ggggccgaac ctgctgatgt acaacactaa aaccttcccg acgccgccgg
     7801 atagctggca agtggttttt gttgagcaaa atctgccgga cggcaagagc aataaaggcc
     7861 gcgttcaggc ttatgatggc cctatctata ttgcggacgc tgcgttgttc gttaaagcca
     7921 ctcagccgca gttgggcatc agcgatccgt atcaactcac cgaagaacag taccaggcgg
     7981 tgctgaaagt gctgcgcgct caacacagtt tgatccatcg ctactggcat gacactaccg
     8041 tgcaaatgag cgatttcaaa aacgagggtg tggttgcttc cagtgcctgg ccctatcagg
     8101 ccaacgccct gaaagccgaa ggccagcctg ttgctaccgt tttcccgaag gagggtgtta
     8161 ccggttgggc tgataccacc atgctgcata gcgaagcgaa acatccggtt tgcgcctaca
     8221 aatggatgaa ctggtcatta acgccaaaag tgcagggcga tgtggcggcc tggtttggct
     8281 cgttaccggt agtgccggaa gggtgtaaag ccagtccgtt attaggcgaa aaaggttgtg
     8341 aaaccaacgg ttttaactat ttcgacaaaa tcgccttctg gaaaacgcct atagcagaag
     8401 ggggcaagtt tgttccctac agtcgctgga cgcaggatta cattgccatt atgggcggtc
     8461 gctaacttcg ctggggtgct ttatgacgta cgcagtggag tttgacaacg tctcgcggtt
     8521 gtacggtgac gtgcgcgcag tagatggcgt cagtattgcg ataaaagatg gtgagttctt
     8581 ctctatgctg gggccgtccg gctccggcaa aaccacctgc ctgcgcctga ttgctggctt
     8641 cgaacagctt tccggcgggg ctatctctat ctttggtaaa cccgccagca atctgccacc
     8701 gtgggagcgg gacgtgaata ctgtctttca ggactacgcg ctatttccgc atatgtcgat
     8761 tcttgacaat gtcgcctatg ggctgatggt caaaggcgtg aataaaaagc agcggcacgc
     8821 aatggcgcaa gaggcgctgg agaaagtggc gttggggttt gtacatcaac gtaaaccgtc
     8881 acaactttct ggtggtcagc gccagcgggt tgctatcgcc agagcattgg tgaatgaacc
     8941 gcgcgtattg ctgttggatg aaccgctcgg cgcactggat ctcaaattgc gtgagcagat
     9001 gcagctggaa ctgaaaaaac tgcaacagtc tctcggtatc acttttatct tcgttaccca
     9061 cgatcagggc gaagcgttat cgatgtccga tcgtgtggcg gttttcaata atggacgcat
     9121 tgagcaggtc gattccccgc gcgatctcta tatgcgcccg cgcacgccgt ttgttgccgg
     9181 gttcgttggt acatcgaatg tttttgatgg actgatggca gagaaacttt gtggcatgac
     9241 gggaagcttc gccctgcgac cggaacatat ccgcctcaac acccctggtg aactgcaggc
     9301 caatggcacg atccaggcgg tgcaatatca gggcgcggca actcgttttg aactgaaatt
     9361 gaacggcggt gaaaaactgc ttgtgagtca ggccaatatg acaggcgaag aactgcctgc
     9421 cacgctcacg cccggacaac aggtgatggt ttcctggtcg cgtgatgtga tggtgccgct
     9481 ggttgaggag aggtgaatgg cgatgaatgt attgcaatca ccttcacgtc caggtctggg
     9541 taaggtgtcc ggtttcttct ggcataatcc ggggctgggg ctgtttttac tgctgcttgg
     9601 cccgctaatg tggtttggca ttgtctattt cggctcgctg ctgacactgt tatggcaggg
     9661 attttatact tttgacgatt tcaccatgtc ggtaacgccg gaactgacgc tggcgaatat
     9721 ccgtgcgctg tttaatccgg cgaattacga catcattctc cgcacgctga ctatggctgt
     9781 ggcagtcact atcgccagcg ccattctggc ttttccaatg gcgtggtata tggcgcgcta
     9841 taccagcggg aaaatgaaag cgttttttta tattgcggta atgttgccga tgtgggcgag
     9901 ctacattgtt aaagcctatg cctggacgtt attgctggca aaagatggcg tggctcagtg
     9961 gtttttacaa catcttgggc tggaaccact gctgactgcg ttccttacat tacctgcggt
    10021 gggcggaaat acgctgtcaa cttccgggct ggggcgcttt ctggtgtttc tctatatctg
    10081 gttgccgttc atgatcctgc ccgttcaggc ggcgcttgag cgtttgccgc cgtcattgtt
    10141 gcaggcgtcg gctgatctcg gcgcacgtcc acgacaaacc tttcgctatg tggtgctgcc
    10201 gctggcaatc ccgggtattg ccgctggctc tatctttacc ttctcactca cactgggcga
    10261 ttttatcgtc ccgcagctgg ttggtcctcc aggatatttt atcggcaata tggtttattc
    10321 ccagcagggg gcgattggca atatgccgat ggcggcggca ttcaccctgg tgccgattat
    10381 tctcatcgca ctgtacctgg cgttcgtgaa acgtctggga gcgttcgatg cactctgaac
    10441 gcgcaccgtt tttcctcaaa ctggcggcct ggggcggcgt tgttttccta cattttccca
    10501 tcctgataat cgccgcctat gcgtttaaca ctgaagatgc ggcgtttagt tttccaccgc
    10561 agggcctgac gctgcgctgg tttagcgtgg cagcacagcg tagtgatatt cttgatgccg
    10621 tgacactgtc acttaaagtg gcggcgctgg cgacattaat tgcgctggtg ttagggacgc
    10681 tggcagctgc cgcgctgtgg cgacgagact ttttcggcaa aaacgccatt tcgctgttac
    10741 tgctgctgcc cattgcgctg ccgggcattg tcactggtct ggcgttatta accgccttta
    10801 aaaccatcaa tctggagccg ggatttttca ccatcgtggt cggtcatgcg actttttgtg
    10861 tagttgtggt gtttaacaat gtcatcgccc gttttcgccg cacctcctgg agtctggttg
    10921 aggcgtcaat ggatcttggg gccaatggct ggcaaacctt ccgctacgta gtgttgccga
    10981 atctcagttc ggcgttactg gcaggaggaa tgctggcgtt tgccttgtcg ttcgatgaaa
    11041 tcatcgttac gacctttacg gcaggtcatg aacgaacgtt accgttgtgg ttgctcaatc
    11101 agcttgggcg accgcgtgat gtaccggtaa ctaacgtggt ggcactgctg gttatgttgg
    11161 taacaacctt gccgatcctg ggggcctggt ggctaacccg cgaaggcgac aatggtcaat
    11221 aaccactgat acaggaatat gctatgcaac ataagttact gattaacgga gaactggtta
    11281 gcggcgaagg ggaaaaacag cctgtctata atccggcaac gggggacgtt ttactggaaa
    11341 ttgccgaggc atccgcagag caggtcgatg ctgctgtgcg cgcggcagat gcagcatttg
    11401 ccgaatgggg gcaaaccacg ccgaaagtgc gtgcggaatg tctgctgaaa ctggctgatg
    11461 ttatcgaaga aaatggtcag gtttttgccg aactggagtc ccgtaattgt ggcaaaccgc
    11521 tgcatagtgc gttcaatgat gaaatcccgg cgattgtcga tgtttttcgc tttttcgcgg
    11581 gtgcggcgcg ctgtctgaat ggtctggcgg caggtgaata tcttgaaggt catacttcga
    11641 tgatccgtcg cgatccgttg ggggtcgtgg cttctatcgc accgtggaat tatccgctga
    11701 tgatggccgc gtggaaactt gctccggcgc tggcggcagg gaactgcgta gtgcttaaac
    11761 catcagaaat taccccgctg accgcgttga agttggcaga gctggcgaaa gatatcttcc
    11821 cggcaggcgt gattaacata ctgtttggca gaggcaaaac ggtgggtgat ccgctgaccg
    11881 gtcatcccaa agtgcggatg gtgtcgctga cgggctctat cgccaccggc gagcacatca
    11941 tcagccatac cgcgtcgtcc attaagcgta ctcatatgga acttggtggc aaagcgccag
    12001 tgattgtttt tgatgatgcg gatattgaag cagtggtcga aggtgtacgt acatttggct
    12061 attacaatgc tggacaggat tgtactgcgg cttgtcggat ctacgcgcaa aaaggcattt
    12121 acgatacgct ggtggaaaaa ctgggtgctg cggtggcaac gttaaaatct ggtgcgccag
    12181 atgacgagtc tacggagctt ggacctttaa gctcgctggc gcatctcgaa cgcgtcagca
    12241 aggcagtaga agaggcgaaa gcgacagggc acatcaaagt gatcactggc ggtgaaaagc
    12301 gcaagggtaa tggctattac tatgcgccga cgctgctggc tggcgcatta caggacgatg
    12361 ccatcgtgca aaaagaggta tttggtccag tagtgagtgt tacgcccttc gacaacgaag
    12421 aacaggtggt gaactgggcg aatgacagcc agtacggact tgcatcttcg gtatggacga
    12481 aagatgtggg cagggcgcat cgcgtcagcg cacggctgca atatggttgt acctgggtca
    12541 atacccattt catgctggta agtgaaatgc cgcacggtgg gcagaaactt tctggttacg
    12601 gcaaggatat gtcactttat gggctggagg attacaccgt cgtccgccac gtcatggtta
    12661 aacattaagg ataatattgc agatcgtaag agtatgagat gatcttgcgt actgtcagag
    12721 cactgatttc tctgacagta cgtgctgcgt gcaaaatcac tacatcaaat aaaccagcca
    12781 aatctcatag agataagagt aaacaaacca acagcagcaa agaaatttat cagtactaca
    12841 gttctactgg aaacattcat ttttgccacc ttttatcatt gcccctatgt gtatagtacg
    12901 ggttaagaaa atccgcaata atactcattc tgaagatgga taagggcaag ttgctgtttg
    12961 atgatttttt ctcaaactgg tgaaaaaact tgatgcacgt caaaaaatga cgcatatttg
    13021 cgcgcgtttt attcatctgg ctggacgccc gtacatgtct ctctatcaac acatgcttgt
    13081 tttttatgcg gttatggcag caatcgcatt tcttatcacc tggtttcttt ctcacgataa
    13141 gaaacgcatc cgtttcttaa gcgcctttct ggtgggggca acatggccga tgagtttccc
    13201 ggtggcgctg ttgttttcac tgttttaaat cttactcact ggcttgacgg caccacgcag
    13261 acttatatca tttggatgaa tcgataaatt tcacaagtgg ctaaggagaa agtatgtcgc
    13321 atctggatga agtcatcgcg cgcgtggatg ccgcgattga agagagcgtc attgcccata
    13381 tgaacgaatt attaatcgcc ctgagcgatg acgcggagtt aagtcgggaa gatcgctaca
    13441 cccagcagca acgtctgcgc acagcgatcg cccatcacgg tcgcaagcat aaagaagata
    13501 tggaagcgcg ccacgaacag ttaaccaaag gcggcaccat cctctgatta aaatgagcgt
    13561 ctggctacca accaggcgcc aaccacaagt aaaattgcgc cacaaattgg gccgaacaac
    13621 gcccgtagtg gtacgccatg actgcggaag atatccagca tcagaccgcc aatcagctga
    13681 ctggcgacca gtacagcaat agttgtcgcc gctcccacat tctgatatcc gctgatactg
    13741 gcgaagacaa aaaacgatcc cagcaagcca ggtataagtg tccaccagcg cacgctggac
    13801 accagttcgc caaaccccgc cataccttgt ttaaaccata aaatagaaac aaagagcaca
    13861 atccccacca gtgagttcag caacatggcg atgagaatgg tagaggaggt ctgggtgatg
    13921 cgcaccatca gcgtgttctg gacaaccaga ccaattccgg cggcaatcaa aaaagcaagg
    13981 gtgagcgact gattcatcca atcgcgtccg gttcagtgcg ctcgtcgagt tgcaactgca
    14041 taaatgtcag atccagccaa cgaccaaatt tagtgcctac ctgcggcatt tgcgcggtga
    14101 cgacaaatcc cagcgactgg tggagatgca gcgaggcctg attttgcgat tcgatcccgg
    14161 cgaccatgac atgcttcccg caatcccgcg cttcatcaat caatcggctt aacaatttac
    14221 gccccagacc tttgccctga tgatcgggat ggacataaac cgaatgttcc acggtatggc
    14281 gaaaaccatc gaaactacgc cagtcgccaa acgaggcata tcccgtcact acgccgtttt
    14341 cctcgctcac cagcactgga taacctgcta aagtccgcgc ttcaaaccag gcaatgcggt
    14401 tatcagcatc caccgtttgg tcattccaga tagccgccgt atacaacacg gcgtggttat
    14461 aaatttccgc aatggcagca cagtcggctt tgcgggcaaa acggatggac atgtctggcc
    14521 tcaataaaat aatgatgatg atgttatcaa tactatcgaa aacagcccga agcaacggat
    14581 tcctcgatga aattattgcg tgttgcagag gggatgtgac ggctgcaaac aaaaccaatc
    14641 ccgtgagcct gctactattg atggattcat gccaaaagca caggagagca ttatggggca
    14701 acaaaagcag cgtaatcgac gttgggttct ggcctcgcgt ccacatggcg cacctgttcc
    14761 ggagaatttc cgtcttgaag aagatgatgt cgccacaccg ggtgaaggac aggtgttact
    14821 gcgcacagtt tatttgtccc tggacccgta tatgcgtgga cgtatgagcg atgagccatc
    14881 ttattcaccg cctgttgata ttggcggcgt gatggtcggc ggtacggtga gccgtgtcgt
    14941 ggagtcgaat catcctgatt atcagtctgg cgactgggtg ctgggctaca gtggatggca
    15001 agactatgac atatccagtg gtgatgatct ggtgaaactt ggcgatcatc cgcaaaatcc
    15061 atcgtggtcg ctgggtgtgc tagggatgcc aggctttacc gcttatatgg gcctactgga
    15121 tatcggtcag cctaaagagg gcgaaacgtt ggtggtagct gcggcgacag gaccagtggg
    15181 ggcgacggtg gggcaaatcg gcaaacttaa aggttgcaga gtggtggggg tagccggtgg
    15241 cgcggaaaaa tgccgccatg ctaccgaggt gttaggcttc gatgtttgtc ttgatcacca
    15301 cgcggatgat tttgccgaac aactggcgaa agcgtgccca aaaggtattg atatctatta
    15361 tgaaaacgtg ggcggtaagg tattcgatgc ggtgctaccg ttacttaata catctgcgcg
    15421 cattcccgtc tgcggattag tgagcagcta taacgctaca gagctaccac ccggtccgga
    15481 tcgtttacct ctgttgatgg ctacagtgct gaaaaaacgt attcgcttgc aaggttttat
    15541 tatcgctcag gattatggtc accgcatcca tgagtttcag agggagatgg ggcaatgggt
    15601 gaaagaggat aaaatccact accgcgaaga aattactgac ggtttagaga atgcgccaca
    15661 gacgtttatc ggcctgctga agggtaaaaa cttcggcaaa gtggtgatcc gcgtggcggg
    15721 tgatgattaa agtttcaacg gcggcgtaag ccgccataaa aatccaggca aaaagcttat
    15781 tttcagcttt aattaactaa ccacatcatt gttctgctgc taataacaac aaaggtgagt
    15841 ggtttatgat tattcacttt aatacaccag gtgaattcct tctgccatgc aggcagggtt
    15901 ggacagaaaa cacgcgaagg aattaaaatg cctggaacgg gaaaaatgaa acatgtcagt
    15961 ttgactctgc aggttgagaa cgacctgaaa catcagctta gtattggcgc attaaaacct
    16021 ggcgcacgcc tgattactaa aaatctggcg gagcaattag gtatgagtat tacacctgtg
    16081 cgtgaagcat tattacgtct ggtttcggtg aatgcgcttt ctgtcgcacc tgcacaagca
    16141 tttacagttc cggaagtggg gaaacgtcaa ttagacgaaa tcaatcggat ccgctacgaa
    16201 ctggaattaa tggcagttgc tctggctgtt gaaaacctca ccccgcaaga ccttgcggaa
    16261 ctccaggaat tgctcgagaa attacagcag gcgcaagaaa agggcgacat ggaacaaatc
    16321 attaatgtaa acaggctatt tcgcttagcg atttatcatc gctcaaatat gcccatcctg
    16381 tgtgagatga ttgagcaact gtgggtcagg atggggcctg gtttacatta tctctatgaa
    16441 gcgattaatc cagcggaatt acgggagcat atagaaaact atcatctgtt actcgctgcg
    16501 ttaaaagcaa aagacaaaga gggatgcaga cattgtcttg ctgaaattat gcaacaaaat
    16561 attgctattt tataccagca atactatcgt taaagtaaat gcccggcaaa taccgggcat
    16621 caaggtaatt actcaaatct ccacgcaata ttcatgccga caccataatt tcgtccgggc
    16681 gaaggttcgt aatatcgccc gtttgactca ttgacaatga cagaaccaac gtattcttta
    16741 tcgaataaat tatcgacacg accaaataaa tccacagtta aattgtggca attgtattta
    16801 tacccggtga ataagccgac gagagtataa gacggcgctt ttgccgtatt ttcatcatct
    16861 gccataatat cgcccatata acgcgcttcc gtgcctgcat accaaccatc ttccggtaca
    16921 taacctatcg acgcaaagcc catattacgg gcgatccctg gcatccgatt accgttacaa
    16981 tcctgttcat tgcaaacatt gctgcgatag gtcgcatcaa gccaggtcca ggacgcgttt
    17041 acgcgaaaat ctcctgcgaa acgttgatcc catgccagtt cagcgccttg acgacgggtc
    17101 tttccggcat ttttgtaagt cgtacgccca ccgctactgc tatcgacaac aatttcatca
    17161 tcagtgtcgg tctgaaacaa tgcgagacta agcagcccat caccaatacg cgttttactg
    17221 ccgatctcaa ttgtatcgtt ggtggatggt tttaaaccta agttcatacc gctttgccca
    17281 tcagcacgat aagacagctc attaatcgtc ggcgtttcaa aacctcgccc ggctgccaga
    17341 tagatattcc aggcatcggt cattgcatat tttaacgaac cggcaggtag ccatttatga
    17401 taactggcat caccgctgtc atcgccgtta cccggagtaa cgtaatggtc gttggaatca
    17461 aaccacacgg agctgtagcg cacgccagca tccagcgaca gtttttcgct cagctgccac
    17521 tgcgtctgta aatagggatc gatgttccac atcagattgc gttcgtcgcg acgcaactca
    17581 cctttttgcc cgtactccgg catgccgcta ttcaggcgga agttattgta gcccttgcgg
    17641 ttttcactca tgttttcgta gttcaggccg gtagtgaacg tgaccggaac gcccagttca
    17701 ccacggtgtg tccagcggct gtctattccc tggtaatggc gttgcagggt aatcacgccg
    17761 cccgcatgtg acgggttaag ttgtggtgcc atgggtattg actggtactg ggtcgtttct
    17821 cgctctccgg catacatcat cacactcata tcatcccgcg aactcaggct acgctcatag
    17881 cgcaacccag cctgagtttg cttgatggtt tttcgcgtgt cgtactgttc tgcacgaggc
    17941 gcttgttgtg gattagcctt ccattctgct ttggttagcc cacctgggtc atctgctttg
    18001 atatccacac tattgaaaat cagacttaat ttgctggctt catcaatgcg tacgcccagt
    18061 ttggcattgg ctaaattttt ctgtgcgcca ctatggtcac gatagccgtg ggtcgtaaaa
    18121 cgcgtggttg agacggtgta atcgacatcg ccaggctgtg tgccgtctcc cgttgcgccc
    18181 gttgctttca gcccatagcg ccagctgcca aaactgccgt agtaactact ggcttcaatg
    18241 gttggtggct gttgtccggt ctgggtggtg acattcatta ccccaccaga cgcgttgcca
    18301 tacagggcag agaaggggcc acgcagcact ttcacatttt gcacactgct taaatcgatg
    18361 ttggatgttt gcccttgccc gtcgggcatg gtggcgggaa taccgtccac atacaggcga
    18421 ataccgcgaa taccgtaagt ggagcgggag ccaaatccgc gaatcgacag ctgtaaatct
    18481 tgcgcatagt tctgccggtt ttgtacctgc aaaccaggca cgccggtcag tgattcggac
    18541 aagttaatgc gcggtgttgc caggcgcatc tcctcgccat ccaccacgct tactgctgct
    18601 ggggtatcca gttctgaaac cacctgcggt gcggcactga caatcatagt ctgttcatca
    18661 gcggcaaaaa caacggggga aaggacaagc agtgcgggca aaacggtctg tcggacggaa
    18721 aaaatcttca tgaaaaaagc caggttaaga atgggaaaac gccgtcatgg taatgaaatt
    18781 gtaaatttat ggaaaatgaa acggcacaat acgttaagta attgagaaaa ttgtagtcgt
    18841 aacggcaaga aatgctccac atttgagaaa ataatgatta ccattcccat ttataacaag
    18901 agcgtaacga tgattacgct tagcgaagca ttgtgaagca gcaaaaatat cggttcatca
    18961 aagggagtcg tcatgcattt acgtcatctg ttttcatcgc gcctgcgtgg ttcattactg
    19021 ttaggttcat tgcttgttgt ttcatcattc agtacgcagg ccgcagaaga aatgctgcgt
    19081 aaagcggtag gtaaaggtgc ctacgaaatg gcttatagcc agcaagaaaa cgcgctgtgg
    19141 ctcgccactt cgcaaagccg caaactggat aaaggtggcg tggtttatcg tcttgatccg
    19201 gtcactctgg aagtgacgca ggcgatccat aacgatctca agccgtttgg tgccaccatc
    19261 aataacacga ctcagacgtt gtggtttggt aacaccgtaa acagcgcggt cacggcgata
    19321 gatgccaaaa cgggcgaagt gaaaggccgt ctggtgctgg atgatcgtaa gcgcacggaa
    19381 gaggtgcgcc cgctgcaacc gcgtgagctg gtagctgacg atgccacgaa caccgtttac
    19441 atcagtggta ttggtaaaga gagcgtgatt tgggtcgttg atggcgggaa tatcaaactg
    19501 aaaaccgcca tccagaacac cggtaaaatg agtaccggtc tggcgctgga tagcgaaggc
    19561 aaacgtcttt acaccactaa cgctgacggc gaattgatta ccatcgacac cgccgacaat
    19621 aaaatcctca gccgtaaaaa gctgctggat gacggcaaag agcacttctt tatcaacatt
    19681 agccttgata ccgccaggca gcgtgcattt atcaccgatt ctaaagccgc agaagtgtta
    19741 gtggtcgata cccgtaatgg caatattctg gcgaaggttg cggcaccgga atcactggct
    19801 gtgctgttta accccgcgcg taatgaagcc tacgtaacgc atcgtcaggc aggtaaagtc
    19861 agtgtgattg acgcgaaaag ctataaagtg gtgaaaacgt tcgatacgcc gactcatcca
    19921 aacagcctgg cgctgtctgc cgatggcaaa acgctgtatg tcagtgtgaa acaaaaatcc
    19981 actaaacagc aggaagctac ccagccagac gatgtgattc gtattgcgct gtaatagata
    20041 tggcgagggt gaaaacggtg agacttgcct gccttttatc acggcgtatc cggcactttc
    20101 gtcagtaatc tgaatttgcc cggcacgtag ccgggcaatt ttgcaattaa ctcgccgttt
    20161 caggcttaaa cacaatttcc tgtttttctt catcttcctc gacgactggc gcagtgctgt
    20221 gaatttcagc aacgcgtttg cgcacaccaa accagcctat aaccagcaaa ataccgataa
    20281 tcggcagcgc cgcgatagta taagtcccgt tcgggtaatc gaacgccatc agcacaagga
    20341 cactcagtaa aaacagtaat gtcagccagg aagtgaaggg cgcgccaggc agtttaaaac
    20401 tgacatccgc tgctttgcct tctttaatcg ctttacgcag gcgcatctgg cacacgatga
    20461 taaacgccca tgaagcgatg attcccagcg acgcgaagtt caacacaatc tcaaatacgc
    20521 gcgacggcac cagatagttg aggaatacgc cgacgacata cacaactagt gtcgccagaa
    20581 tcccggcata cggcacatgc tgacgactca ttttcgccat aaaactcggt gcggaaccgc
    20641 ccatcgccat tgagcgcaga atacgtccgg tgcagtacag acctgaattc aggctggaga
    20701 gggcagcggt cagcaccaca atgttcataa tgctgccgat atatggcaca cccagtttag
    20761 agaaaaacgt cacgaacgga ctttgccccg cctgatacgc gctccacggc aataacataa
    20821 ccagcaacac cacggagccg acgtaaaaca ggccaatacg ccaaatcaca ctgttaatgg
    20881 ctttaggcac catggtctgc ggatctttac attctccggc agctgtaccc accatttcaa
    20941 tggaggcaaa agcaaacact acgccctgaa tcaacaccag cgcaggcagc aaaccgtggg
    21001 ggaagaagcc gccattatcg gtgattaaat gaaagccagt ggtgttgcca tccagcggct
    21061 gaccactacc gaggaacact gtacccacga ccaaaaaggt cacaatggcg agcactttaa
    21121 taagcgcaaa ccagaactcc atctccgcaa accatttcac accgatcata ttcatggtgc
    21181 caacgatggt aagtgcagcg agcgcaaaga cccactgcgg cacgccgcca aacgcacccc
    21241 agtaatgcat atacagagcg acggcggtaa tatcaacaat ccccgtcatc gcccagttga
    21301 tgaagtacat ccagccagca acataagcgg ctttctcacc caaaaactca cgggcataag
    21361 aaacaaaact gccactggaa gggcggtgta gcaccagctc acccaatgca cgcagaataa
    21421 aaaacgaaaa caagccacaa attaaataaa ccagtgccag tgcgggcccc gccatttgca
    21481 gtcgggctcc tgcacctaaa aacaagccgg tgccaatcgc gccgccaatg gcgatcatct
    21541 gcacctggcg attgcccatc gctttgtgat acccctcttc gtgggcatta agccagcggc
    21601 gtttcgcggc gtgttgatct gaagtgtcgg tgtcgtgttt actcattgct ctccctgatt
    21661 gctttaatga aaaagtcata taagttgcca tgaacaatgt ttattcatcc tggcgatgat
    21721 agttatcacc attattcttt atgggtataa aactatcggc gcagcatcct acccgttatc
    21781 gataaacgat gcaaaacatc cccttacaat cctgaagggg attaatacaa ctgacgaaaa
    21841 aatgacaaat ccttttgctg gttaacctgt gtactgtcct acacttaatc tttaaaagat
    21901 tgtgaggggc atatgattaa ggtgtatggc gtacccggat ggggctctac aatcagtgag
    21961 ctgatgctaa cactggctga tattccttat cagttcgttg atgtcagtgg ttttgaccac
    22021 gagggagctt cacgcgagtt attgaaaacc ctgaacccgt tgtgtcaggt tccgacactg
    22081 gcattggaaa atgacgagat tatgacggag acagcggcga ttgcattgat ggttctcgat
    22141 cgtcgcccgg accttgcgcc accggttggg cgcgccgaac gtcagctgtt tcaacggcta
    22201 ttggtctggc tggttgctaa tgtctatcca acattcactt tcgccgatta ccctgagcgt
    22261 tgggctcctg acgcacctga acagttaaag aagaatgtta ttgaatatcg aaaatcgctt
    22321 tatatctggt tgaattcgca gctcactgct gaaccttatg cgtttggtga gcaactaacg
    22381 ctggtggact gttatctttg cactatgcgc acatgggggc ctgggcatga atggtttcag
    22441 gataatgcca cgaatatcag tgcgattgct gatgctgtat gtcagttacc gaaattacaa
    22501 gaagtattaa aaaggaatga aattatttga gtgggatacc agaagattat gttatttatt
    22561 attcagtaac tttatccaca atgatgggcg taattaatta aattcatggt atgtttttta
    22621 atttatatca ctctcctttt cattcagcgt gtctatttca tttcctctga
//
LOCUS       DACAOP010000076        22339 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.076, whole genome shotgun sequence.
ACCESSION   DACAOP010000076 DACAOP010000000
VERSION     DACAOP010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22339
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.076"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..274
                     /locus_tag="IT892_003170"
     CDS             <1..274
                     /locus_tag="IT892_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136358.1"
                     /translation="QLIAGETLFTGTINRTEVHPREVIKRALYHNAAAVVLAHNHPSG
                     EVTPSKADRLITERLVQALGLVDIRVPDHLIVGGNQVFSFAEHGLL"
     gene            337..558
                     /locus_tag="IT892_003171"
     CDS             337..558
                     /locus_tag="IT892_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HAP3136359.1"
                     /translation="MKIIPRGEAMRIHQQHPASRLFPFCTGKYRWHGSAETYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            620..1042
                     /locus_tag="IT892_003172"
                     /pseudo
     CDS             620..1042
                     /locus_tag="IT892_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389100.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
     gene            1351..1503
                     /locus_tag="IT892_003173"
     CDS             1351..1503
                     /locus_tag="IT892_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001316510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136360.1"
                     /translation="MHSLMNSQARDTRDRSLNDDNVLEISEPRIRSTFERLYQNMNEA
                     FGLGDY"
     gene            complement(1583..2830)
                     /locus_tag="IT892_003174"
     CDS             complement(1583..2830)
                     /locus_tag="IT892_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136361.1"
                     /translation="MALNIPFRNAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLT
                     GTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFILVLTGPFMIYVYEPLL
                     QSNFSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFF
                     AGIFFSISPHINFWLVSLFGAVFMMINMRFKDKDHQCIAADAGGVKKEDFIAVFKDRN
                     FWVFVIFIVGTWSFYNIFDQQLFPVFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAI
                     IPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAIEVPLCVISVFKY
                     SVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLL
                     FGIFFLSKKREQIVMETPVPSAI"
     gene            complement(2892..3815)
                     /locus_tag="IT892_003175"
     CDS             complement(2892..3815)
                     /locus_tag="IT892_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoimidazole riboside kinase"
                     /protein_id="HAP3136362.1"
                     /translation="MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGT
                     SGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVR
                     PSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTAIRHAGGFVSFDPNIR
                     EDLWQDEHLFRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLV
                     TKGAEGVVVCYRGQVHHFAGMSVNCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRI
                     INLAQRCGALAVTAKGAMTALPCRQELEGEK"
     gene            4031..5464
                     /locus_tag="IT892_003176"
     CDS             4031..5464
                     /locus_tag="IT892_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP3136363.1"
                     /translation="MTQSRLHAAQNALAKLHERRGNTFYPHFHLAPPAGWMNDPNGLI
                     WFNDRYHAFYQHHPMSEHWGPMHWGHATSDDMIHWQHKPIALAPGDENDKDGCFSGSA
                     VDDNGVLSLIYTGHVWLDGAGNDDAIREVQCLATSRDGIHFEKQGVILTPPEGIMHFR
                     DPKVWREADTWWMVVGAKDPGNTGQILLYRGSSLREWTFDRVLAHADAGESYMWECPD
                     FFSLGDQHYLMFSPQGMNAEGYSYRNRFQSGVIPGMWSPGRLFAQSGHFTELDNGHDF
                     YAPQSFLAKDGRRIVIGWMDMWESPMPSKREGWAGCMTLARELSESNGKLLQRPVHEA
                     ESLRQQHQSISPRTISNKYVLQENAQAVEIQLQWALKNSDAEHYGLQLGTGMRLYIDN
                     QSERLVLWRYYPHENLDGYRSIPLPQGDMLALRIFIDTSSVEVFINDGEAVMSSRIYP
                     QPEERELSLYASHGVAVLQHGALWQLG"
     gene            complement(5472..6530)
                     /locus_tag="IT892_003177"
     CDS             complement(5472..6530)
                     /locus_tag="IT892_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP3136364.1"
                     /translation="MDLASDVCFCYSARFTANGLGMASLKDVARLAGVSMMTVSRVMH
                     NAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQGRKPSTLAVLAQDTATTPFSVDIL
                     LAIEQTASEFGWNSFLINIFSEDDAARAARQLLAHRPDGIIYTTMGLRHITLPESLYG
                     ENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYRQPLCFWLPESALATGYRRQ
                     GFEQAWRDAGRDLAEVKQFHMATGDDHYTDLASLLNAHFKSGKPDFDVLICGNDRAAF
                     VAYQVLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPHDIIGREAALHIIEDR
                     EGGRVTRIPCPLLIRCST"
     gene            6710..6928
                     /locus_tag="IT892_003178"
                     /pseudo
     CDS             6710..6928
                     /locus_tag="IT892_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416866.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
     gene            6946..8274
                     /gene="dsdA"
                     /locus_tag="IT892_003179"
     CDS             6946..8274
                     /gene="dsdA"
                     /locus_tag="IT892_003179"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HAP3136365.1"
                     /translation="MENAKMNSLIAQYPLVKDLVALQETTWFNPGTTSLAEGLPYVGL
                     TEQDVQDAHARLSRFAAYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQ
                     LLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQ
                     YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGV
                     AVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAEQSRIVDADNPLFVYL
                     PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNL
                     TAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMA
                     GPQRVCASVSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMEQYLAKGR"
     gene            complement(8382..9920)
                     /gene="emrY"
                     /locus_tag="IT892_003180"
     CDS             complement(8382..9920)
                     /gene="emrY"
                     /locus_tag="IT892_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrY"
                     /protein_id="HAP3136366.1"
                     /translation="MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTI
                     SGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSL
                     STNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPI
                     LGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVG
                     GLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWESTSENPILDLSLFKSRNFTI
                     GIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPIGIMPLLISPLIGRYGNK
                     IDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTISFS
                     GLPDNKFANASSMSNFFRTLSGSVGTSLTMTLWGRRESLHHSQLTATIDQFNPVFNSS
                     SQIMDKYYGSLSGVLNEINNEITQQSLSISANEIFRMAAIAFILLTVLVWFAKPPFTA
                     KGVG"
     gene            complement(9920..11083)
                     /gene="emrK"
                     /locus_tag="IT892_003181"
     CDS             complement(9920..11083)
                     /gene="emrK"
                     /locus_tag="IT892_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrK"
                     /protein_id="HAP3136367.1"
                     /translation="MEQINSNKKHSNRRKYFSLLAVVLFIAFSGAYAYWSMELEDMIS
                     TDDAYVTGNADPISAQVSGSVTVVNHKDTNYVRQGDILVSLDKTDATIALNKAKNNLA
                     NIVRQTNKLYLQDKQYSAEVASARIQYQQSLEDYNRRVPLAKQGVISKETLEHTKDTL
                     ISSKAALNAAIQAYKANKALVMNTPLNRQPQVVEAADATKEAWLALKRTDIKSPVTGY
                     IAQRSVQVGETVSPGQSLMAVVPARQMWVNANFKETQLTDVRIGQSVNIISDLYGENV
                     VFHGRVTGINMGTGNAFSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEHPLRIGLSM
                     TATIDTKNEDIAEMPELASTVTSMPAYTSKALVIDTSPIEKEISNIISHNGQL"
     gene            11499..12113
                     /gene="evgA"
                     /locus_tag="IT892_003182"
     CDS             11499..12113
                     /gene="evgA"
                     /locus_tag="IT892_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system DNA-binding response
                     regulator EvgA"
                     /protein_id="HAP3136368.1"
                     /translation="MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETL
                     KPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSK
                     KEGMNNIIAAIEAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKD
                     NNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG"
     gene            12118..15711
                     /gene="evgS"
                     /locus_tag="IT892_003183"
     CDS             12118..15711
                     /gene="evgS"
                     /locus_tag="IT892_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system histidine kinase EvgS"
                     /protein_id="HAP3136369.1"
                     /translation="MKFLPYIFLLCCGLWSTISFADEDYIEYRGISSNNRVTLDPLRL
                     SNKELRWLASKKNLVIAVHKSQTATLLHTDSQQRVRGINADYLNLLKRALNIKLTLRE
                     YADHQKAMDALTEGEVDIVLSHLVASPPLNDDIAATKPLIITFPALVTTLHDSMSPLT
                     SSKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGQNDYFIGSNIITSS
                     MISRYFTHSLNVVKYYNSPRQYNFFLTRKDSVVLNEVLNRFVDALTNEVRYEVSQNWL
                     DTGNLAFLNKPLELTEHEKQWIKQHPDLKVLENPYSPPYSMTDETGSVRGVMGDILNI
                     ITLQTGLNFSPITVSHNIHAGTQLNPGGWDILPAAIYSEDRENNVLFAEAFITTPYVF
                     VMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIKVDNASAAFHKVKEGELD
                     ALVATQLNSRYMIDHYYPNELYHFLIPGVPNASLSFAFPRGEPELKDIINKALNAIPP
                     SEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKV
                     IQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENS
                     DSPFKDVFSNAHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASDHAVYI
                     CGWQDITETRDLIHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGS
                     GLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHS
                     FGAIAASKSIALSCSSTFPEHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLG
                     DIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNM
                     LGDLSLESHPGIGTTFTITIPVEITQQVATVEAKAEQPMTLPEKLSILIADDHPTNRL
                     LLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFELTRKLREQNSS
                     LPIWGLTANAQANEREKGLNCGMNLCLFKPLTLNVLKTHLSQLHQVAHIAPQYRHLDI
                     EALKNNTAKDLQLMQEILMTFQHETHKDLPAAFHALEAGDNRTFHQCIHRIHGAANIL
                     NLQKLINLSHQLEITPVSDDSKPEILKLLNSVKEHIAELDQEIAVFCQQND"
     gene            complement(15767..16912)
                     /gene="yfdE"
                     /locus_tag="IT892_003184"
     CDS             complement(15767..16912)
                     /gene="yfdE"
                     /locus_tag="IT892_003184"
                     /EC_number="2.8.3.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416872.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA:oxalate CoA-transferase"
                     /protein_id="HAP3136370.1"
                     /translation="MTNNECKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPP
                     GHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFR
                     PGTMEKLGFSWETLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYS
                     DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMA
                     YIATGKSPQRLGNRHPYMAPFDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPR
                     FSSNILRVQNQAILKQYIERTLKTQAAEVWLAKIHEVGVPVAPLLSVAEAINLPQTQA
                     RNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS"
     gene            complement(16986..17930)
                     /gene="yfdV"
                     /locus_tag="IT892_003185"
     CDS             complement(16986..17930)
                     /gene="yfdV"
                     /locus_tag="IT892_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter YfdV"
                     /protein_id="HAP3136371.1"
                     /translation="MLTFFIGDLLPIIVIMLLGYFSGRRETFSEDQARAFNKLVLNYA
                     LPAALFVSITRANREMIFADTRLTLVSLVVIVGCFFFSWFGCYKFFKRTHAEAAVCAL
                     IAGSPTIGFLGFAVLDPIYGDSVSTGLVVAIISIIVNAITIPIGLYLLNPSSGADGKK
                     NSNLSALISAAKEPVVWAPVLATILVLVGVKIPAAWDPTFNLIAKANSGVAVFAAGLT
                     LAAHKFEFSAEIAYNTFLKLILMPLALLLVGMACHLNSEHLQMMVLAGALPPAFSGII
                     IASRFNVYTRTGTASLAVSVLGFVVTAPLWIYVSRLVS"
     gene            complement(17999..19693)
                     /gene="oxc"
                     /locus_tag="IT892_003186"
     CDS             complement(17999..19693)
                     /gene="oxc"
                     /locus_tag="IT892_003186"
                     /EC_number="4.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxalyl-CoA decarboxylase"
                     /protein_id="HAP3136372.1"
                     /translation="MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAE
                     GIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMI
                     SGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPG
                     GVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVASAISLLAKAERPLVIL
                     GKGAAYSQADEQLREFIESAQIPFLPMSMAKGILEDTHPLSAATARSFALANADVVML
                     VGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELK
                     QNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLV
                     NEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAF
                     GFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDA
                     FRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQVAGN"
     gene            complement(19747..20997)
                     /gene="frc"
                     /locus_tag="IT892_003187"
     CDS             complement(19747..20997)
                     /gene="frc"
                     /locus_tag="IT892_003187"
                     /EC_number="2.8.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyl-CoA transferase"
                     /protein_id="HAP3136373.1"
                     /translation="MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDV
                     TRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAI
                     DHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPP
                     LVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRL
                     DKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQN
                     WENTCKAIGKPDWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIP
                     CAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEH
                     TAAVLQELGYSDDEIAAMKQNHAI"
     gene            complement(21509..22141)
                     /locus_tag="IT892_003188"
     CDS             complement(21509..22141)
                     /locus_tag="IT892_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HAP3136374.1"
                     /translation="MKRLIMATMVTAILASSTVWAADNAPVAAQQQTQQVQQTQKTAA
                     AERISEQGLYAMRDVQVARLALFHGDPEKAKELTNEASALLSDDSTEWAKFAKPGKKT
                     NVNDDQYIVINASIGISESYVATPEKEAAIKIANEKMAKGDKKGAMEELRLAGVGVME
                     NQYLMPLKQTRNALADAQKLLDKKQYYEANLALKGAEDGIIVDSEALFVN"
BASE COUNT         6363 a         5255 c         4831 g         5890 t
ORIGIN      
        1 tcagctgatt gccggtgaaa ccctcttcac cggcaccatc aaccgcacgg aagtccatcc
       61 ccgggaagtg attaaacgcg ccctgtacca caatgccgct gccgtggtgc tggcgcacaa
      121 tcacccgtcc ggtgaagtca cacccagtaa ggcagaccgg cttatcaccg aacgtctggt
      181 acaggcactg ggcctggtgg atatccgggt gccggaccat ctgatagtcg gtggcaacca
      241 ggttttctcc tttgccgaac atggtctgct ttaacccgtc acaaccacat cacacctgtt
      301 ttcactttta tcttctgtct tcagaggtat cccattatga aaattatccc ccgtggtgaa
      361 gccatgcgta ttcaccaaca gcatcctgca tcccgtcttt ttccgttctg taccggtaaa
      421 taccgctggc acggcagtgc tgagacgtat accggtcgtg aagtgcagga tattcccggt
      481 gtgctggccg tgtttgctga acgccgtaag gacagttttg gtccgtatgt ccggctgatg
      541 agcgtcaccc tgaactgagt cagggcattc tgatgagcag aattatcgcc actaccggac
      601 cattcttaac cgattttctg tgaggacttt atcgtgtcag acacactcca cgacgacaac
      661 acttcccgac gacaatcacg accgcccctg gtgggggctg ccctgcaccg tgacgccctg
      721 tttcggcgcc cgtctggtgc aggagggtaa ccggttgcat taacttgcag accgcgccgg
      781 tatcagaggc cggttcagcg atgcggatgc ataccatctg gaccaggcct ttccactgct
      841 gatgaaacaa ctggaactca tgctcaccag cggtgaactg aatccccgcc atcagcatac
      901 catcacactg tatgcaaaag ggctgacctg tgaagctgat actctcggca gttgtagttt
      961 cgtttatatg gctgtttatg ctacccgatt ctcaaatcaa ttaccgaaag cttctgttca
     1021 tcaactaact cattactttt aatgatgggg ccctttctgg ggcccaagaa attaacaacg
     1081 ctaacaaaca acataaataa caataaatta aataaaaaat ttcattcctg caggggacac
     1141 cagataccct tcaaaccaaa tctaccttca ccccgtaaaa gatgggtttg gcgcacacta
     1201 gccctatatc tactcatttt tactgcaaca ggttgaaatc tcagcactgt cagaaagcgc
     1261 tgatgactaa acagccctgg gccgggcgat gtaaccatca tacagaatcc tgatagcgaa
     1321 atatggcgtg actcgatact tcactctgca atgcattcct tgatgaattc gcaggcccgt
     1381 gatactcggg acaggtcgct gaatgacgac aatgtcctgg aaatcagcga accgcgtatc
     1441 cggagtacat ttgagcgact gtaccagaac atgaatgagg cgtttggatt aggtgattat
     1501 tagttgggct aagcattttt gtattattat tttccggttg agggatatgg agatatcgac
     1561 aacaaccgga aaaagtttac gtctatattg ctgaaggtac aggcgtttcc ataactattt
     1621 gctcgcgttt tttactcagg aagaaaatgc caaatagcaa catcaggcag acaatacccg
     1681 aaattgcgaa gaaaactgtc tggtagcctg cgtggtcaaa gagtatccca gtcggcgttg
     1741 aaagcagcac aatcccaagc gaactggcaa tttgaaaacc aatcagaaag atcgtcgacg
     1801 acaggcgctt atcaaagttt gccacgctgt atttgaagac ggatatgaca caaagtggaa
     1861 cctcaatggc atgtaacagc ttcactaatg aaataatcca ggggttaacg aacaacgcgc
     1921 aggaaaggat acgcaacgcc ataatcacaa caccgataag taatgcattt tttggcccta
     1981 cccgattcac aaagaaagga ataatcgcca tgcacagcgc ttcgagtacc acctggaatg
     2041 agttgagata accatacagg cgcgttccta catcgtgtga ttcgaataaa cctgcataaa
     2101 agacaggaaa gagttgttga tcaaaaatgt tatagaaaga ccacgtcccc acaataaata
     2161 tgacgaaaac ccagaagttt cgatccttga aaactgcgat aaaatcctct ttttttaccc
     2221 ctcccgcatc cgccgctatg cactggtgat ccttatcttt aaaacgcatg ttgatcatca
     2281 taaatacagc gccaaatagc gagaccaacc agaagttgat atggggactg atactaaaaa
     2341 atataccggc aaagaacgcg ccaatagcat agccaaaaga tccccaggcg cgcgctgttc
     2401 catattcgaa atgaaaattt cgcgccattt tttcggtgaa gctgtcaagc aaaccgcatc
     2461 ccgccagata ccccaggcca aaaaagagcg cccccagaat tagacctaca gaaaaattgc
     2521 tttgcagtaa cggttcataa acgtaaatca taaacggtcc ggtcaagacc agaatgaaac
     2581 tcatacacca gatgagcggt ttcttcagac cgagtttatc ctgaacgatg ccgtagaaca
     2641 tcataaatag aatgctggta aactggttga ccgaataaag tgtacctaat tccgtccctg
     2701 ttaatcctag atgtcctttc agccaaatag cgtataacga ccaccacagc gaccaggaaa
     2761 taaaaaagag aaatgagtaa ctggatgcaa aacgatagta cgcatttctg aatggaatat
     2821 tcagtgccat aattacctgc ctgtcgttaa aaaattcatg tcctatttag agataagagc
     2881 ggcctcgccg tttacttctc accttccagt tcttgtcgac atggcagcgc tgtcattgcc
     2941 cctttcgctg ttactgcaag cgctccgcaa cgttgagcga gattgataat tcgtcgcatt
     3001 tctctctcat ctgtagataa tcccgtagag gacagacctg tgagtaaccc ggcaacgaac
     3061 gcatctcccg ccccagtgct atcgacacaa ttcacagaca ttccagcaaa atggtgaact
     3121 tgtcctcgat aacagaccac caccccttct gcacctttag tcaccaacag catggcgatc
     3181 tcatactctt ttgccagcgc gcatatatcc cgatcgttct gtgtttttcc actgataagt
     3241 cgccattctt cttccgagag cttgacgaca tccgccagtt gtagcgcctg ccgcaaacac
     3301 aagcggaaca aatgctcgtc ttgccataga tcttcacgaa tattgggatc gaagctgaca
     3361 aaacctccgg catgccggat cgccgtcatc gcagtaaatg cgctggtacg cgaaggctcg
     3421 gcagacaacg caattgaaca gagatgtaac cattcgccat gtcgccagca gggcaagtct
     3481 gtcgtctcta aaaaaagatc ggcactgggg cggaccataa acgtaaatga acgttctcct
     3541 tgatcgttca gatcgacaag caccgtggat gtccggtgcc attcatcttg cttcagatac
     3601 gtgatatcga caccctcagt tagcagcgtt ctttgcatta acgcaccaaa aggatcatca
     3661 ccgacccgac ctataaaccc acttgttccg cctaatctgg cgattcccac cgcaacgtta
     3721 gctggcgcgc cgccaggaca aggcagtagc cgcccgtctg attctggcaa gagatctacg
     3781 accgcatccc ctaaaaccca tactttggct gacatttttt tcccttaaat tcatctgact
     3841 tacgcatagt gataaacctc tttttcgcaa aatcgtcatg gatttactaa aacatgcata
     3901 ttcgatcaca aaacgtcata gttaacgtta acatttgtga tattcatcgc atttatgaaa
     3961 gtaatggact ttatttttat aaaagttaac gttaacaatt caccaaattt gcttaaccag
     4021 gatgataaaa atgacgcaat ctcgattaca tgcggcgcaa aacgcactag caaaacttca
     4081 cgagcgccga ggtaacactt tctatcccca ttttcacctc gcgcctcctg ccgggtggat
     4141 gaacgatcca aacggcctga tctggtttaa cgatcgttat cacgcgtttt atcaacatca
     4201 cccgatgagc gaacactggg ggccaatgca ctggggacat gccaccagcg acgatatgat
     4261 ccactggcag cataagccta ttgcgctagc gccaggagac gagaatgaca aagacgggtg
     4321 tttttcaggt agtgctgtcg atgacaatgg tgtcctctca cttatctaca ccggacacgt
     4381 ctggctcgat ggtgcaggta atgacgatgc aattcgcgaa gtacaatgtc tggctaccag
     4441 tcgggatggt attcatttcg agaaacaggg tgtgatcctc actccaccag aaggaatcat
     4501 gcacttccgc gatcctaaag tgtggcgtga agccgacaca tggtggatgg ttgtcggggc
     4561 gaaagatcca ggcaacacgg ggcagatcct gctttatcgc ggcagttcat tgcgtgaatg
     4621 gaccttcgat cgcgtactgg cccacgctga tgcgggtgaa agctatatgt gggaatgtcc
     4681 ggactttttc agccttggcg atcagcatta tctgatgttt tccccgcagg gaatgaatgc
     4741 cgagggatac agttaccgaa atcgctttca aagtggcgta atacccggaa tgtggtcgcc
     4801 aggacgactt tttgcacaat ccgggcattt tactgaactt gataacgggc atgactttta
     4861 tgcaccacaa agctttttag cgaaggatgg tcggcgtatt gttatcggct ggatggatat
     4921 gtgggaatcg ccaatgccct caaaacgtga aggctgggca ggctgcatga cgctggcgcg
     4981 cgagctatca gagagcaatg gcaaacttct acaacgcccg gtacacgaag ctgagtcgtt
     5041 acgccagcag catcaatcta tctctccccg cacaatcagc aataaatatg ttttgcagga
     5101 aaacgcgcaa gcagttgaga ttcagttgca gtgggcgctg aagaacagtg atgccgaaca
     5161 ttacggatta cagctcggca ctggaatgcg gctgtatatt gataaccaat ctgagcgact
     5221 tgttttgtgg cggtattacc cacacgagaa tttagatggc taccgtagta ttcccctccc
     5281 gcagggtgac atgctcgccc taaggatatt tatcgataca tcatccgtgg aagtatttat
     5341 taacgacggg gaggcggtga tgagtagccg aatatatccg cagccagaag aacgggaact
     5401 gtcgctctat gcctcccacg gagtggctgt gctgcaacat ggagcactct ggcaactggg
     5461 ttaacataat atcaggtgga acaacggatc aacagcgggc aagggatccg cgtcactctt
     5521 cccccttcac gatcttcaat aatatgcaat gcagcttccc gcccgataat gtcatgtgga
     5581 agctgaattg tggtcagcgg cggtaaaaac agatgcccga cgccaaccag attatcaaag
     5641 cccattacgg cgacatcctg cgggatacgt acccccttcg ccaggagaac ctgataagcg
     5701 acaaaggctg cgcgatcgtt accacatatc agaacatcaa aatctggttt gccagatttg
     5761 aagtgggcat tgagtaaact tgcgagatcg gtgtagtgat catcacctgt tgccatgtga
     5821 aattgtttca cctcagccag atctcgtcca gcatcacgcc aggcctgctc aaatccctgc
     5881 cgacgatacc ctgttgccaa cgcactttcc ggtagccaga agcataacgg ttgacgatag
     5941 cccgccgcga gcaaatgctg tgttgattca tattgtgcag tgtaatcatc agggatataa
     6001 ctgggtaacg ctgggtcatc cgccacacag ttcgccaata caatattttc accatacaga
     6061 gactcaggca gcgtgatatg tcgcagcccc attgtagtat agataatgcc atccggacgg
     6121 tgggcaagca gctgacgagc agcacgggca gcgtcatctt cagaaaaaat attgattaaa
     6181 aaactattcc agccgaactc gctggcggtt tgctcaatgg caagcagaat atcaacagag
     6241 aaaggagtgg tagcagtgtc ctgcgccagc acggcgagag tcgacggctt acgtccttga
     6301 gcgcgcatct tacgggcgga aagatcagga acataattca gggtctggat tgcctgcaat
     6361 acgcggtcac gcgttgcagg acgcacagat tctgcattat gcatcacccg ggagactgtc
     6421 atcatcgaca ctcccgccag gcgtgcgaca tcctttaatg aagccatacc caagccgttt
     6481 gccgtaaaac gggcactgta gcagaaacag acgtcactgg cgagatccaa cgatattctc
     6541 gacgccctat cacccgacac ggcaatacaa taaaaaataa caataattcc cggacaattg
     6601 tacccaattc cgcctctgtt ctcgccaacg agtaaccatg taggcaagta ggtaaaacat
     6661 gccaactggc atcgccaacc tggagaagaa aatataaata tggatcattg tgctgccgct
     6721 gtatcccgac atcagcccgg aaattattgc gattgctatc ggttcaggtg cgattggctg
     6781 cacgatcgtt acggactcgc ttttctggct ggtgaagcaa tattgcggcg ctacgctcaa
     6841 tgaaacattt aaatactata cgaccgcgac atttatcgct tcagtcgtcg ctctggcggg
     6901 cacattcctg ctgtcattta tcatctaagc gcaaagagac gtactatgga aaacgctaaa
     6961 atgaactcgc tcatcgccca gtatccgttg gtaaaggatc tggttgctct tcaagaaacc
     7021 acctggttta atcctggcac gacctcattg gctgaaggtt taccttatgt tggcctgacc
     7081 gaacaggatg ttcaggacgc ccatgcgcgc ttatcccgtt ttgcagccta tctggcaaaa
     7141 gcatttcctg aaactgctgc tactgggggg attattgaat cagaactggt tgccattccg
     7201 gctatgcaaa aacggctgga aaaggaatat caacaaccga tcagcgggca actgctactg
     7261 aaaaaagata gccatttgcc catttccggc tccataaaag cacgcggcgg gatttatgaa
     7321 gtcctggcac atgcagaaaa actggctctg gaagcggggt tgctgacgct tgaagatgac
     7381 tacagcaaac tgctttctcc ggagtttaaa cagttcttta gccaatacag cattgctgtg
     7441 ggctcaaccg gaaatctggg gttatcaatc ggcattatga gcgcccgcat tggctttaag
     7501 gtgacagtac atatgtctgc tgatgcccgg gcatggaaaa aagcgaaact gcgcagccat
     7561 ggcgttacgg tcgtggaata tgagcaagat tatggtgttg cagtcgagga aggacgtaaa
     7621 gcagcgcagt ctgacccgaa ctgtttcttt attgatgacg agaattcccg cacgttgttc
     7681 cttgggtatt ccgtcgctgg ccagcgtctt aaagcgcaat ttgccgagca aagtcgtatt
     7741 gtcgatgctg ataaccctct gtttgtctat ctgccgtgtg gtgttggcgg tggtcctggt
     7801 ggcgtcgcat tcgggcttaa actggcattt ggcgatcatg ttcactgctt ttttgccgaa
     7861 ccaacgcact ccccttgtat gctgttaggc gtccatacag gattacacga tcagatttct
     7921 gttcaggata ttggtatcga caaccttacc gcagcggatg gccttgcagt tggtcgcgca
     7981 tcaggctttg tcgggcgggc aatggagcgt ctactggatg gcttctatac ccttagcgat
     8041 caaaccatgt atgacatgct tggctggctg gcgcaggaag aaggcattcg tcttgaacct
     8101 tcggcactgg cgggtatggc cgggcctcag cgcgtgtgcg catcagtaag ttaccaacag
     8161 atgcacggtt tcagcgcaga acaactgcgt aatgccactc atctggtgtg ggcgacggga
     8221 ggtggaatgg tgccggaaga agagatggag caatatctgg caaaaggccg ctaattactt
     8281 ttcaattcag catcgccatc ctttccctgg gtgagcgatg ctgccgatgg cgcagactta
     8341 aggtccctgg tcttacctgc tataaccccc tccttttatc atcacccaac gcctttcgct
     8401 gtaaacggcg gtttcgcaaa ccaaaccaaa actgtaagta agataaaagc aatagccgcc
     8461 atacggaaaa tctcatttgc agaaattgaa agtgactgct gagttatttc attattaatt
     8521 tcattaagaa cccctgaaag cgaaccatag tatttatcca taatttgtga cgatgaatta
     8581 aacacggggt taaattgatc gatggttgct gtcaactgac tatggtgtaa cgattcgcgt
     8641 cgtccccaca gcgtcattgt caacgacgta ccaactgatc ctgacaaggt gcgaaaaaaa
     8701 ttactcatac tcgaggcatt ggcaaattta ttatctggca accctgaaaa cgaaatcgtt
     8761 gttaagggta aaaagaaaca ggcaacggcg aatccctgga aaaactgtgg caaaatgatg
     8821 cctgtaaaat caatcgttgg cataaatgtc acagaacgcc agtaatagca aaccgcatac
     8881 attaaaaaac taaatgtcac caacaaccgc atatcaattt tgttgccata acgtcctatc
     8941 aaaggtgata ttaatagcgg catgatgccg atgggcgcat aggcaagtcc ggcccatatc
     9001 gcattatacc ccatcgtttc ctggagtaac tgcggcataa ggactatcgc cccagagtaa
     9061 aataaatacg cgcatgtgat actcacaata ccaatggtga aattacggga cttaaacaaa
     9121 ctgagatcaa gaatcgggtt ctctgaggtc gactcccaaa tgactaaaga aatcagagaa
     9181 ataactgaca ctactgttag tattattatt gtactcgagt tgaaccaatc caggtcgcgc
     9241 cctttatcaa gcattatctg caagccacca acaccgagca ctaacagggt cagtcctggt
     9301 agattcattt tgaccggtga agtctcagtt tctcttcctt taagtaaggt taagcataat
     9361 gtcagaacga taatccccat agggacattg attaaaaata tccaacccca gctaaagtta
     9421 tcacaaatat aaccgcccaa tatcggccca catatcggcg cgataatcac ggtcatagac
     9481 cataatgcca gagcaaatgt tcttttttct ggtggataat tccttaataa taaactctgt
     9541 gacagtggaa ttaacggccc cgccattaac ccctgaacga ctctaaaaaa tatcagcaca
     9601 tcaagattgg tcgataggct acacattaat gaagatagcg aaaaaaaggt tactgaaagt
     9661 aaaaataatc ttaattcgcc tattctttgt gccaacctgc cggtaacagg gatcgcaatg
     9721 gcatttgcta caccaaacga agtgataacc caggtgcctt cgtctgttga tgctcccaga
     9781 aagccagata ttgtcggtat tgcgacgtta gaaatagtgg aatccaacat ttgcataaac
     9841 gtcgctaatg acaatgcaat agtgacgcac cataacgtcc caccggttaa tggtgccgga
     9901 gttgatttag tgattgccat taaagttgtc cattatgcga aataatgttg ctaatttctt
     9961 tttctatcgg actggtatcg ataactaaag ccttactggt ataagcaggc atggacgtca
    10021 cggttgaagc cagctcaggc atctcggcaa tgtcttcgtt cttcgtatca atagttgctg
    10081 tcatcgataa accaatacgt aagggatgtt ccatgagttc ttttggatca agagaaactt
    10141 caaccggtac acgctgaacg attttgatcc agttccctgt cgcattttgt gcaggtaata
    10201 aggagaacgc attgccggtt cccatattga tccctgtcac ccgaccatga aacacaacat
    10261 tttcaccata aagatcgctg ataatattga ccgattgacc aatccgtaca tccgtgagtt
    10321 gtgtttcttt aaagttggca ttaacccaca tttgacgtgc cggtacgaca gccattaacg
    10381 attgtccggg actcactgtt tcgccgacct gaacgcttct ctgggcaata tagccggtaa
    10441 caggactctt aatatccgta cgtttaagcg ctaaccaggc ttctttggtt gcatccgccg
    10501 cttcaacgac ttgtggctga cggtttaatg gtgtgttcat tactaaagct ttattcgctt
    10561 tataagcctg gatagcggca ttcaatgccg ctttgctact tattaacgta tctttggtat
    10621 gctccagcgt ttcttttgaa ataaccccct gcttcgctaa aggtacacga cggttataat
    10681 cttctaaaga ttgttgatac tgaatacgtg ctgaagcgac ttcggcactg tattgtttat
    10741 cctgtaagta cagtttattc gtttgccgaa caatattggc cagattattt ttagctttat
    10801 tgagtgcgat agtggcatca gtcttatcca gtgagactaa aatgtcaccc tgtcgaacgt
    10861 agttcgtatc tttatgatta acgacagtga cgctgcctga aacttgtgca gaaattggat
    10921 ctgcattccc cgtgacatag gcatcatctg tactaatcat gtcttctaat tccattgacc
    10981 aataggcata ggcacctgaa aacgcaataa ataaaactac cgccaataaa gaaaagtatt
    11041 ttcttctgtt agaatgtttt ttatttgaat taatctgttc cactattatc tctcatttcg
    11101 catagatgaa atttatgaat tgaatgaaaa gagtattcat tcttcatatc aaacacagtg
    11161 catgtgttgc acattgtccc aggaacgttg gaggcctaat ttaaatgagg tgcaaaaaaa
    11221 acaacagagg actaaaccgt ggcttttgca atacaattct tacgcatgta ggattagtga
    11281 gaagacttat agtactaatg tgaaactata aatcatcggt acaatccctg attttattgt
    11341 tgacatttca tatatgccga ctatttatat ggtatacttg tcgaattatc ttaaaggaag
    11401 ctcaaatttt cttattttta ttgagaaaat gagatgatgc cttatgtctg tattactaca
    11461 gggagaaggg agatgcttca ttgcaaaggg aataatctat gaacgcaata attattgatg
    11521 accatcctct tgctatcgca gcaattcgta atttattgat caaaaacgat attgaaatct
    11581 tagcggagtt gactgaaggg ggaagtgccg ttcagcgggt ggaaacactt aaacctgata
    11641 tcgtcatcat tgatgtcgat atccccggag ttaacggtat ccaggtgtta gaaacgctga
    11701 ggaagcgcca atatagcgga attattatta tcgtctccgc taaaaatgac catttttacg
    11761 ggaaacattg tgctgatgct ggcgctaatg gattcgtgag taaaaaagaa ggcatgaaca
    11821 atatcattgc ggctattgaa gctgcaaaaa atggctactg ctatttcccc ttctctctca
    11881 accggtttgt tggaagttta acgtccgacc agcaaaaact cgactcctta tcgaaacaag
    11941 aaattagtgt catgcgatat attcttgatg gcaaggataa taatgacatt gctgaaaaaa
    12001 tgttcatcag caacaaaact gtcagcactt ataaaagtcg cctgatggaa aaattagaat
    12061 gtaaatcact gatggatctt tacacattcg cacaacgtaa caaaatcggc taaccacatg
    12121 aagtttttac cctatatttt tcttctctgt tgtggtcttt ggtcgaccat aagtttcgca
    12181 gacgaagatt acatcgaata tcgtggcatc agtagtaaca accgtgtcac gcttgatcca
    12241 ctacgtctga gcaacaagga attacgttgg ttagcgagca aaaaaaatct tgtgattgca
    12301 gtacacaagt cccaaacggc tactttgttg cataccgatt cgcagcaacg ggttcgtggt
    12361 attaatgctg attatttaaa tcttttaaaa agagcgttaa atattaaatt aacactccgg
    12421 gaatacgcag atcatcaaaa agcaatggac gcgcttacag aaggggaagt cgatatagtg
    12481 ttatcacatt tagttgcttc gccgcctctt aatgatgaca ttgctgcaac caaaccgctg
    12541 ataattacct ttccggcgct ggtcaccacc cttcacgatt caatgagccc gcttacctca
    12601 tcaaaaccag taaatattgc tcgggtagca aattaccctc cagatgaggt aattcatcaa
    12661 tcatttccaa aagcaacaat tatctctttt acaaatttat atcaggcatt agcatccgtc
    12721 tcagccggac agaatgatta ctttattggt agtaacatta ttaccagcag tatgatttcc
    12781 cgctatttca ctcactcctt aaatgtagtg aaatattata actcgccgcg tcaatataac
    12841 tttttcttaa ccagaaaaga ttcagtcgtt cttaatgaag tactcaatcg atttgttgat
    12901 gctttaacaa atgaagttcg ctatgaagta tcacaaaatt ggcttgatac aggaaacctg
    12961 gcctttctga acaaaccatt agaactcact gaacatgaaa aacagtggat taagcagcat
    13021 cccgatttaa aggtgctgga aaatccttac tcgccaccct attctatgac agatgaaact
    13081 ggctcagttc ggggcgtgat gggtgatatt cttaatatta ttaccttgca aacaggttta
    13141 aatttttctc cgatcaccgt ttcacacaat attcatgcgg ggacacagct taaccccggt
    13201 ggatgggata tattgcccgc cgctatttat agtgaagata gagaaaataa tgttttattt
    13261 gctgaagcct tcataacaac gccttacgtt tttgtcatgc aaaaagcgcc tgacagtgaa
    13321 caaacattaa aaaaaggaat gaaagttgcc attccctatt attatgagct tcattcgcaa
    13381 ttaaaagaga tgtatccgga ggtagagtgg ataaaagtcg ataacgccag cgctgcattt
    13441 cacaaggtca aggaaggcga acttgatgct ctggtcgcga cacagttaaa ttcacgttac
    13501 atgatcgacc attactatcc taatgaactt tatcattttc ttattcccgg cgttccgaat
    13561 gcatcgcttt cgttcgcttt tcctcgcgga gaaccggaac ttaaggatat tattaataaa
    13621 gcactgaatg caattccccc aagcgaagtt ctgcgcctga cggaaaaatg gattaaaatg
    13681 cccaatgtga ccattgacac atgggacctc tatagcgagc aattttatat tgtcacgaca
    13741 ttatccgttt tattagttgg cagtagcctt ttatggggat tctacctgtt acgctcagtt
    13801 cgtcgtcgta aagtcattca gggtgattta gaaaaccaaa tatcattccg aaaagcactc
    13861 tcggattcct taccgaatcc aacttatgtt gtaaactggc aaggtaatgt cattagtcat
    13921 aatagtgctt ttgaacatta tttcactgcg gattactaca aaaatgcaat gttaccatta
    13981 gaaaacagtg actcaccctt taaagatgtt ttttctaatg cgcatgaagt tacagcagaa
    14041 acgaaagaaa atcgaacaat atacacacag gtatttgaaa ttgataatgg catcgagaaa
    14101 agatgcatta atcactggca tacattatgc aatctgccag ccagcgatca tgctgtttat
    14161 atttgtggtt ggcaagatat taccgagacg cgtgatttaa ttcatgcact cgaggtagag
    14221 agaaataaag cgatcaatgc aactgtcgca aaaagccagt ttctggcaac aatgagtcac
    14281 gaaataagaa caccaataag ctccattatg ggcttcctgg aacttctgtc gggttctggt
    14341 cttagcaagg agcaacgggt ggaggcgatt tcacttgcct acgccaccgg acaatcactc
    14401 ctcggcttaa ttggtgaaat ccttgatgtc gacaaaattg aatcgggtaa ctatcaactt
    14461 caaccacaat gggtcgatat ccctacttta gtccagaaca cttgtcactc tttcggtgcg
    14521 attgctgcaa gcaaatcgat cgcattaagt tgcagcagta cgtttcctga acattacctg
    14581 gttaagatcg accctcaggc gtttaagcag gtcttatcta atttactgag caatgctctc
    14641 aaatttacca ccgagggggc agtaaaaatt acgacctccc tgggtgacat tgatgacaac
    14701 cacgctgtta tcaaaatgac gattatggat tctggaagtg gattatcgca ggaagaacaa
    14761 caacaactgt ttaaacgcta tagccaaaca agtgcaggtc gtcagcaaac aggttctggt
    14821 ttaggcttaa tgatctgcaa agaattaatt aaaaacatgc tgggtgattt gtcattagaa
    14881 agtcatcccg gcataggaac gacatttacg atcacaatcc cggtagaaat tacccaacaa
    14941 gtggcgactg tcgaggcaaa agcagaacaa cctatgacac tccctgaaaa gttgagtata
    15001 ttaatcgcgg atgatcatcc aaccaacagg ctattactca aacgccagct aaacctatta
    15061 ggatatgatg ttgatgaagc cactgatggt gtgcaagcgc tacacaaagt cagtatgcaa
    15121 cattatgatc tgcttattac tgacgttaat atgccgaata tggatggttt tgagttgact
    15181 cgcaaactcc gtgagcaaaa ttcttcctta cccatctggg ggcttacagc caacgcacag
    15241 gctaacgaac gtgaaaaagg gttaaattgc ggcatgaact tatgtttgtt caaaccgttg
    15301 accctgaatg tactgaaaac acatttaagt cagttacacc aggttgcgca tattgcacct
    15361 cagtatcgcc accttgatat cgaggccctg aaaaataata cggcgaaaga tctacaactg
    15421 atgcaggaga ttctcatgac tttccagcat gaaacgcata aagatctacc cgctgcgttt
    15481 catgcgttag aagctggcga taacagaact ttccatcagt gtattcatcg catccacggt
    15541 gcggctaaca tcctgaattt gcaaaagttg attaatctta gccatcagtt agaaataacg
    15601 cccgtttcag atgacagcaa gcctgaaatt cttaagttgc tgaactctgt taaagaacac
    15661 attgcagagc tggaccagga gatagctgtt ttctgtcaac aaaatgacta aatagcggct
    15721 cccacaatat tcaaatgtgg gagctattta ccagcacatc ttacatttat gatgagaact
    15781 cctggcgaat ttgttcccca tgctggtcga gcgttgccgc tcccggcata acatgcgggt
    15841 ccgcgcagcc gctgattttt atcggattac ctggcatcat tattcccccg gcttcaatca
    15901 acatatttct cgcctgagtt tgtggcaaat taatggcctc agccacactt aataacggcg
    15961 cgacgggcac accaacttca tgtattttgg ctaaccaaac ttcagctgcc tgcgttttta
    16021 acgttcgctc aatatattgt ttaagaatag cctggttttg tacgcgtaaa atattgctgc
    16081 taaatcgggg atcattaacc agttccgtaa gctccagtgc ctggcataac gcagaaaaaa
    16141 gcttgtcatt accacaacaa atagtaatcg gcttatcctg agtatcaaaa acatcaaaag
    16201 gtgccatgta gggatggcga tttcccaggc gttgtggtga cttccctgtc gcaatatatg
    16261 ccatcagacc atgctccaga aaactcagcg tggcatcaaa catcgctata tcgacatgcg
    16321 cccctctctg gctcttttcg cggccataaa gtgcactcac tattccgctg aataaataga
    16381 caccgccaca taaatccgca agagaggtac ccacgcgcac tggcggagca tcagagtacc
    16441 ctgtttccat cattatcccg ctcattgcct gaatgatggt atcgtaggca ggagcatctt
    16501 ttagcgggcc ggtatgccca aaacctgacg atgaagcata tatgagacgc gggttgattt
    16561 cttgtagcgt ttcccatgaa aaccccagtt tttccattgt acctgggcga aaattctcag
    16621 ctaatacatc cgcttgttta agcatattta taaatatgct tttatcgtga tcattcttta
    16681 aatcaagaac cacactctct ttgccatgat taataaaact gtaatagagt gactgtccat
    16741 ccacataggg accaaatgtg cgggtatcat caccatgacc tggcggctca actttaatta
    16801 cccttgcgcc catattacaa agaagttgag ttccgaaagg cccattaagg acatgcgtca
    16861 tatcgataac taataagcct tcaaacggcc ctttgcattc attattggtc atttgcttat
    16921 accttgaaaa aagccgaagg tgaaaagaca cttcggcatt tatgtaaaat caataacatg
    16981 attaattatg aaaccagtcg actgacataa atccacaagg gagccgtgac gacaaaaccc
    17041 agtacgctca cagccaatga cgctgtacca gtgcgggtgt agacattaaa ccgactggca
    17101 ataatgattc cggagaatgc cggcggtaat gcgcctgcca gtaccatcat ctgcagatgt
    17161 tcgctgttca aatgacatgc catacccacg agaagcagcg ccagtggcat cagaatcagc
    17221 ttcaggaagg tgttataagc aatttcggca ctgaactcga atttatgtgc agccagagtc
    17281 aaccccgcag cgaataccgc cacccctgag ttagccttcg caatcagatt aaaggttggg
    17341 tcccatgctg ccggaatttt taccccaacc aacaccagga tcgttgccag aacaggtgcc
    17401 catactactg gctcctttgc cgcagaaatt aatgcgctca gattactatt cttcttacca
    17461 tctgctcctg aggaaggatt cagcaaatac agaccaatag gaatagtaat tgcgttaaca
    17521 ataatagaaa taattgctac aactaaacct gttgatacgg aatcaccata aataggatcg
    17581 agaactgcaa atcccaggaa tccgatggta ggtgaacctg caattaatgc acatactgct
    17641 gcttctgcat gagtacgttt aaaaaatttg tagcaaccaa accaggagaa aaagaaacat
    17701 ccgacaataa ccacaagtga tacaagggtc aggcgagtgt ccgcaaaaat catttccctg
    17761 tttgcccggg taatagaaac aaatagggcc gcaggaagag cgtagtttaa taccagttta
    17821 ttaaatgccc gggcttgatc ttctgaaaaa gtttctcgtc tgccgctaaa ataacccaac
    17881 agcatgatta cgataatagg caataaatcg ccaataaaaa atgttagcat aatagtattt
    17941 ccgataaggg tcccctcacc atcgataatg agttggcaag aggagacgat gtcagtattt
    18001 aattaccagc gacttgtttt gggttaagtt tggtaatatg gccactttca gttcctgctg
    18061 cagggtcgat gaccacatta ataatggtcg gtttgcgcga ctgaataccg gtggttaaag
    18121 catgacgaag ttcatctgtc gtagtgacgt tatagccaac gccacgaaac gcatccatta
    18181 atttgtcata ccttgcatgg tgcaatagat ctgttggtga tggtgcacca gcgccactga
    18241 gatcaacacc gtctcctctg tagatgccgc cattattaaa aataacgatc gtcaccggca
    18301 ggttatatcg acaaatcgtt tcaatctcca tcccactgaa accaaaagca ctatcacctt
    18361 caatggcgac aaccggagaa ccagaggtca cgctagcacc gatggcatag cccataccga
    18421 tgcccatgac accccaggtt ccacaatcca gacggcgacg tggtttatac atatcaataa
    18481 tatttcgtgc attatccagg gtatttgcac cttcattaac taaataaata tcctggttct
    18541 cgcgcaatac atcgcgcaca gcacttaatg cattaaagta atttaatggt tgagtatctg
    18601 tacttaattt ttcatgcatt ttttgtgcat tttgctgctt gtggatattt aaaatatcgc
    18661 gccataccag tggagtcgta aatgtgtttt gtttcagttc tgccagcata ccttgcatac
    18721 tggatgcaat atcgccaacg actggcacag caatggggcg gttgctgtca atttcctgcg
    18781 gttcaatatc cagttgaata aactgtgtat ctgccgccca tcctttttta ccgtgtgcca
    18841 gtaaccaatt cagtcgtgca ccaacaagca tgacaacgtc agcatttgcc agggcaaacg
    18901 aacgcgcagt tgccgcagaa agtggatgtg tatcttcgag gatccctttc gccatagaca
    18961 ttggcaggaa tggaatctgg gcactttcaa taaattcacg aagctgttca tccgcttgtg
    19021 aatacgccgc gcctttgcca aggataacta atggtcgttc agcttttgct aaaagcgaaa
    19081 ttgcgctagc gactgacttc gggcatggca ataatgctgg cgacggattt tcaactttta
    19141 caatcgtggt taacgcttcg tctttttcca tcgtcgcggc caggacattt gcaggcaaat
    19201 caagataaac tccgccaggg cgacccgata ctgagacccg gatagcgcgt gccaatgcaa
    19261 tgccaagatc ctgcggctga ttaacgcgaa atgctgcttt ggcatacggt tttgccgcat
    19321 tcatttggtc cagctcttca taatcacctt gctgtaggtc gacgatcgcg cggtcgctgg
    19381 agccgctaat catgatcatc ggaaaaccat ttaccgttgc gttggccaat gcggtcaaac
    19441 cattgaggaa tcctggcgca gacactgtca ggcagatccc tggtttttgg gtaagaaaac
    19501 cgcttgcagc agcggcatag cctgccgact gctcatgacg aaaaccaata taacgaatgc
    19561 cttccgcctg ggcatggcgt gccatatccg tcacaggaat acctacaaca ccataaatag
    19621 tgtcaatatt attctgtttt aatgcttcaa cgatgatatg cataccatct gtcatttgaa
    19681 gttgatctga catgattaat aacctcgaaa tttttataaa ttgggagcca gaagcccccg
    19741 ttaatatcag atggcgtggt tttgcttcat tgcagcaatt tcatcgtcgc tataacccag
    19801 ctcctgcaat acagcagcgg tatgttcacc taatagcggc gcagctttaa tatccggcgt
    19861 aaaggcagag aatttcattg gacaaccaac tgtcagatat tttccacgca atggttgttc
    19921 cacttcaaca acactgccac tttggcgcaa agagggatca agtgaaattt ctttcatact
    19981 taaaaccggt gcacaaggaa tatcaaactg agtcaaatag gccaccgctt catgtttatc
    20041 aatagtgaca gtgtattttt cgatttcagc aaaaatatcg aaaatatgtg gctgtcgggc
    20101 atgggctgta ctgtatgccg gatcggtaat ccaatctggt ttgccgatgg ctttacaggt
    20161 gttttcccag ttttgctcct gaatagtgaa ataaatatag gcgttaggat cggtttccca
    20221 acctttacat ttcaggatcc agccaggctg accgccacca cccgcattac ctccgcgggg
    20281 aactgcatca ccaaatgtgc cattcggata ctgcgggtat tcttccagat aacccaattt
    20341 atcgagacgc tgctggtcgc gtaatttcac gcggcaaagg ttcaatacgg catcctgcat
    20401 tgacatggtg actcgttgcc cacgccccgt tttttcgcga tgcagcaaag cagcaagtaa
    20461 accgatcagt aaatgcattc cggtgttgct gtcacccaac gctgcagcgc ttaccagcgg
    20521 cggaccgtcc caaaaacccg tagtggatgc cgcaccaccc gctgcctgag caacgttttc
    20581 ataggctttt acattcacat aaggcgaaca ctcatcaaac cctttgatcg aaccaaaaat
    20641 cagacgtgga ttgatttctt gaatatgctc ccaggtgaag cccatgtgat caatggcccc
    20701 tggatgaaag ttctcgacta agatatcagc ttcgcggatc agcttttcca ttacctcttt
    20761 gccttccgct gttttggtat ttaattcaat agaacgtttg ttactgttaa gcatggtgaa
    20821 gtaaagcgca tcgatatcag gaatatctcg cagctggtga cgcgttacgt caccaacgcc
    20881 gggacgttca attttaatga cgtcagcgcc aaaccaggcc agcatttgag tacaagatgg
    20941 gccagattgc acaccggtga aatcgagaac tttaattcct tgaagtggag ttgacatagc
    21001 aatacctatt agttaattaa atatgtgtta atttagcgtt tatttaagac ataacgcctc
    21061 tataaataat ccgcaaaata tcgtcgtagc tgcactcgat atttttaaat tcctgtatca
    21121 agtactgaaa atcatttcat cgctacttcc aattcctttc tgcatggtaa gtagtgagga
    21181 cgaaaagaag aatatgataa atattggttc gcggtaatca gagagagccg cgacatttgt
    21241 gatgttattc ttacaactgt aagaagcgcc ggtgatttac aagtaagggt atgattacgc
    21301 tttttaaagc gtaccataaa acataacata ataaatgatt tgtgatgaca cgggattatt
    21361 gcggtttact ttgaggaaga taaaatgcga gtttatagaa ccgcgagcgc caaataattt
    21421 tatgaccaca atctgtcgta ttgtggtcat aaaaaattgt cggctggagg gagttaaatc
    21481 ctttacctca atatactgcc tgtcagcatt agttcacaaa cagtgcttcg ctatcgacga
    21541 tgattccatc ttccgcacct ttaagcgcca ggtttgcctc gtagtattgc tttttatcaa
    21601 gcagtttctg cgcatcagca agtgcattac gagtctgttt gagcggcatc agatattggt
    21661 tttccattac gccaacaccg gccaggcgaa gctcttccat tgcgcccttt ttatcccctt
    21721 tcgccatttt ttcgttggca atttttatcg cggcttcttt ttcgggtgtc gctacataac
    21781 tctcagaaat tccgatagat gcattaatga caatatattg gtcatcattg acattggttt
    21841 ttttacctgg cttagcgaac tttgcccatt cggtactgtc atctgacaac aaagctgaag
    21901 cttcattggt cagttctttt gccttttccg gatcgccatg aaacagagcc aggcgcgcta
    21961 cctgcacgtc acgcatcgca tataaacctt gttcagagat acgctctgct gctgccgttt
    22021 tctgggtttg ctgaacttgc tgagtttgct gttgtgccgc taccggtgca ttatcagccg
    22081 cccatacagt tgaagatgcc agaattgctg tgaccatcgt agccataatt aaacgtttca
    22141 tacttacctc attctttaac agttttagaa aacgccgcca tcatattggg tgagcatgaa
    22201 atgagaaatc agagagcaac ggtcattttg aaagggttat cttacagttg tagttattat
    22261 cgcaagaagt attttagtct tacaattgta ggaatatgct tcctgtcgca gagaactatt
    22321 cttatatacc acaaagaga
//
LOCUS       DACAOP010000077        22039 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.077, whole genome shotgun sequence.
ACCESSION   DACAOP010000077 DACAOP010000000
VERSION     DACAOP010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22039
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.077"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(110..817)
                     /locus_tag="IT892_003189"
     CDS             complement(110..817)
                     /locus_tag="IT892_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAP3136375.1"
                     /translation="MVIGPFINASAVLLGGVLGALLSQRLPERIRVSMTSIFGLASLG
                     IGILLVVKCANLPAMVLATLLGALIGEMCLLEKGVNTAVTKAQNLFRHSRKKPAHESF
                     IQNYVAIIVLFCASGTGIFGAMNEGMTGDPSILIAKSFLDFFTAMIFACSLGIAVSVI
                     SIPLLIIQLTLAWAAALILPLTTPSMMADFSAVGGLLLLATGLRICGIKMFPVVNMLP
                     ALLLAMPLSAAWTAWFA"
     gene            1210..3345
                     /locus_tag="IT892_003190"
     CDS             1210..3345
                     /locus_tag="IT892_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
                     /protein_id="HAP3136376.1"
                     /translation="MKSMNIAASSELVSRLSTHRRVVALGDTDFTDVAAVVITAADSR
                     SGILALLKRTGFHLPVFLYSEHVVELPAGVTAVINGNEQQWLELESAACQYEENLLPP
                     FYGTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGD
                     LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKS
                     NHHGALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFR
                     LAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLLELNE
                     NDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQVRFCPHKRLNNAFMLHASTSPFYP
                     LFAALDVNAKIHEGESGRRLWAECVALGIEARKAILARCKLFRPFIPPVVDGKLWQDY
                     PTSVLASDRRFFSFEPGAKWHGFEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFGVP
                     ATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLAE
                     VLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAH
                     SAYIRGEVELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNL
                     LPGFSPELQGVYSETDADGMKRLYGYVLK"
     gene            complement(3394..4650)
                     /locus_tag="IT892_003191"
     CDS             complement(3394..4650)
                     /locus_tag="IT892_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease"
                     /protein_id="HAP3136377.1"
                     /translation="MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
                     SSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAQVTTPEAMFLVILIN
                     SFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
                     QLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSM
                     LLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLS
                     RYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVE
                     KEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSV
                     VLAFAFMAMFKYKHVRVPTGTQTVSH"
     gene            complement(4852..5931)
                     /gene="mltC"
                     /locus_tag="IT892_003192"
     CDS             complement(4852..5931)
                     /gene="mltC"
                     /locus_tag="IT892_003192"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417438.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltC"
                     /protein_id="HAP3136378.1"
                     /translation="MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQF
                     AHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRA
                     IIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLK
                     NRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTES
                     SFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAM
                     LNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLT
                     TRHPSAESRRYLYKVNTAQKSYRRR"
     gene            complement(5995..6270)
                     /locus_tag="IT892_003193"
     CDS             complement(5995..6270)
                     /locus_tag="IT892_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HAP3136379.1"
                     /translation="MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQH
                     KQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK"
     gene            complement(6298..7350)
                     /gene="mutY"
                     /locus_tag="IT892_003194"
     CDS             complement(6298..7350)
                     /gene="mutY"
                     /locus_tag="IT892_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAP3136380.1"
                     /translation="MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQ
                     VATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVAALHGG
                     KFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEV
                     ENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWSL
                     YPGKKPKQTLPERTGYFLLLQHEDEVLLAQRPPSGLWGGLYCFPQFADEESLRQWLAQ
                     RQIAADNLTQLTAFRHTFSHFHLDIVPMWLPVSSFTGCMDEGNALWYNLAQPPSVGLA
                     APVERLLQQLRTGAPV"
     gene            7511..8230
                     /gene="trmB"
                     /locus_tag="IT892_003195"
     CDS             7511..8230
                     /gene="trmB"
                     /locus_tag="IT892_003195"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAP3136381.1"
                     /translation="MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPV
                     MGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGA
                     CLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVP
                     FAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTK
                     FEQRGHRLGHGVWDLMFERVK"
     gene            8230..8556
                     /locus_tag="IT892_003196"
     CDS             8230..8556
                     /locus_tag="IT892_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417434.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF469 domain-containing protein"
                     /protein_id="HAP3136382.1"
                     /translation="MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDD
                     FINEVIEPNKLAFDGSGYMAWEGLICMQEIGKCTEEHQAIVRKWLEERKLGEVRTSEL
                     FDVWWD"
     gene            8740..9459
                     /locus_tag="IT892_003197"
     CDS             8740..9459
                     /locus_tag="IT892_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2884 domain-containing protein"
                     /protein_id="HAP3136383.1"
                     /translation="MMRKMLLAAALSVTAMTAHADYQCSVTPRDDVIVSPQTVQVKGE
                     NGNLVITPDGNVMYNGKQYSLNAAQREQAKDYQAELRSTLPWIDEGAKSRVEKARIAL
                     DKIIVQEMGESSKMRSRLTKLDAQLKEQMNRIIETRSDGLTFHYKAIDQVRAEGQQLV
                     NQAMGGILQDSINEMGAKAVLKSGGNPLQNVLGSLGGLQSSIQTEWKKQEKDFQQFGK
                     DVCSRVVTLEDSRKALVGNLK"
     gene            9635..10681
                     /gene="ansB"
                     /locus_tag="IT892_003198"
     CDS             9635..10681
                     /gene="ansB"
                     /locus_tag="IT892_003198"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase 2"
                     /protein_id="HAP3136384.1"
                     /translation="MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATK
                     SNYTAGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDDVWLTLAKKINTDCDKT
                     DGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAAD
                     KASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARK
                     HTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKTVF
                     DTLATAAKNGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQ
                     TKDPQQIQQIFNQY"
     gene            10798..11745
                     /locus_tag="IT892_003199"
     CDS             10798..11745
                     /locus_tag="IT892_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1202 family protein"
                     /protein_id="HAP3136385.1"
                     /translation="MKKQWIVGTALLMLMTGNVRADGEPPTENILKDQFKKQYHGILK
                     LDVITLKNLDAKGNQATWSAEGDVSSSDDLYTWVGQLADYELLEQTWTKDKPVKFSAM
                     LTSKGTPASGWSVNFYSFQAAASDRGRVVDDIKTNNKYLIVNSEDFNYRFSQLESALN
                     NQNNSIPALKKDVKALDKQMVAAQKAADAYWGKDANGKQMTREDAFKKIHQQRDDFNK
                     QNDSEAFAVKYDKEVYQPAIAACHKQSEECYEVPIQQKRDFDINEQRRQTFLQSQKLS
                     RKLQDDWITLEKGQYPLTMKVSEINSKKVTILMKIDDIN"
     gene            complement(11870..13006)
                     /gene="hemW"
                     /locus_tag="IT892_003200"
     CDS             complement(11870..13006)
                     /gene="hemW"
                     /locus_tag="IT892_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HAP3136386.1"
                     /translation="MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLL
                     NDLDNDVAYAQGREVKTIFIGGGTPSLLSGPAMQTLLNGVRARLPLAADAEITMEANP
                     GTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAANLASGLGLRSF
                     NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALW
                     DIFEQGHQLLTAAGYQQYETSAYAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDG
                     RILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLEAAPRVEFSQYTGLS
                     EEVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE"
     gene            complement(12999..13592)
                     /locus_tag="IT892_003201"
     CDS             complement(12999..13592)
                     /locus_tag="IT892_003201"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HAP3136387.1"
                     /translation="MQKVVLATGNAGKVRELASLLSDFGLDIVAQTDLGVDSAEETGL
                     TFIENAILKARHAAKVTGLPAIADDSGLAVDALGGAPGIYSARYSGEDATDQKNLQKL
                     LETMKDVPDDQRQARFHCVLVYLRHAEDPTPLVCHGSWPGVITREPAGTGGFGYDPIF
                     FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG"
     gene            complement(13600..13890)
                     /locus_tag="IT892_003202"
     CDS             complement(13600..13890)
                     /locus_tag="IT892_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417428.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggU family protein"
                     /protein_id="HAP3136388.1"
                     /translation="MSAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVD
                     GQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN"
     gene            complement(13887..14453)
                     /gene="yggT"
                     /locus_tag="IT892_003203"
     CDS             complement(13887..14453)
                     /gene="yggT"
                     /locus_tag="IT892_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotic shock tolerance protein YggT"
                     /protein_id="HAP3136389.1"
                     /translation="MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVT
                     QPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVLFKVVTFLPIIWIAGLLILLKTI
                     GLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVL
                     LLYVINMGVAEVLQATGNMLLPGLWMAL"
     gene            complement(14471..15175)
                     /gene="yggS"
                     /locus_tag="IT892_003204"
     CDS             complement(14471..15175)
                     /gene="yggS"
                     /locus_tag="IT892_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate homeostasis protein"
                     /protein_id="HAP3136390.1"
                     /translation="MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIA
                     EAIDAGQRQFGENYVQEGVDKIRHFQELSVTGLEWHFIGPLQSNKSRLVAEHFDWCHT
                     IDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRL
                     RGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTM
                     VRIGTAIFGARDYSKK"
     gene            15193..16173
                     /locus_tag="IT892_003205"
     CDS             15193..16173
                     /locus_tag="IT892_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HAP3136391.1"
                     /translation="MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGRMEAAPFDAPDV
                     EELLREWLDDDQRAILLENGQLDFAVSLAENQRLRGSAFAQRQGISLALRLLPSHCPQ
                     LEQLGAPPVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVE
                     YLYTSQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETG
                     HLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAGLSQKLEVDKQEGRVAL
                     FELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMITFQQSYQQRVKEGRL"
     gene            complement(16347..16763)
                     /gene="ruvX"
                     /locus_tag="IT892_003206"
     CDS             complement(16347..16763)
                     /gene="ruvX"
                     /locus_tag="IT892_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAP3136392.1"
                     /translation="MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNI
                     IERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVE
                     ARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY"
     gene            complement(16763..17398)
                     /locus_tag="IT892_003207"
     CDS             complement(16763..17398)
                     /locus_tag="IT892_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708713.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HAP3136393.1"
                     /translation="MTAPFFPRILGAVAFLNQETEPLTMNLQHHFLIAMPALQDPIFR
                     RSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPL
                     AEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDVLVALGYASWEKG
                     QLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTMPGVAGHA"
     gene            complement(17435..18385)
                     /gene="gshB"
                     /locus_tag="IT892_003208"
     CDS             complement(17435..18385)
                     /gene="gshB"
                     /locus_tag="IT892_003208"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HAP3136394.1"
                     /translation="MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLY
                     LINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATYIL
                     ERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILK
                     PLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEP
                     VPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIG
                     DRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ"
     gene            complement(18398..19129)
                     /gene="rsmE"
                     /locus_tag="IT892_003209"
     CDS             complement(18398..19129)
                     /gene="rsmE"
                     /locus_tag="IT892_003209"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311849.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAP3136395.1"
                     /translation="MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFD
                     GSNQVFDAEITSASKKSVEVKVLEGQLDDRESPLHIHLGQVMSRGEKMEFTIQKSIEL
                     GVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWC
                     AEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLG
                     PRVLRTETTALTAITALQVRFGDLG"
     gene            complement(19209..19916)
                     /gene="endA"
                     /locus_tag="IT892_003210"
     CDS             complement(19209..19916)
                     /gene="endA"
                     /locus_tag="IT892_003210"
                     /EC_number="3.1.21.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease I"
                     /protein_id="HAP3136396.1"
                     /translation="MYRYLSIAAVVLSAAFSGPALAEGINSFSQAKAAAVKVHADAPG
                     TFYCGCKINWQGKKGVVDLQSCGYQVRKNENRASRVEWEHVLPAWQFGHQRQCWQDGG
                     RKNCAKDPVYRKMESDMHNLQPSVGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKEK
                     AAEPPARARGAIARTYFYMRDQYNLTLSRQQTQLFNAWNKMYPVTDWECERDERIAKV
                     QGNHNPYVQRACQARKS"
     gene            complement(20011..20508)
                     /locus_tag="IT892_003211"
     CDS             complement(20011..20508)
                     /locus_tag="IT892_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HAP3136397.1"
                     /translation="MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRG
                     TSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWM
                     MESVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGE
                     QLVAK"
     gene            complement(20585..21979)
                     /locus_tag="IT892_003212"
     CDS             complement(20585..21979)
                     /locus_tag="IT892_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAP3136398.1"
                     /translation="MPDAKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIA
                     DEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAA
                     PNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
                     DTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTS
                     AEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPK
                     IFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAAGMGVL
                     GTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTA
                     TNWIANMIVGATFLTMLNTLGNANTFWVYAALNVLFILLTLWLVPETKHVSLEHIERN
                     LMKGRKLREIGAHD"
BASE COUNT         5405 a         5569 c         5847 g         5218 t
ORIGIN      
        1 gggcaacggg gcgcattaaa cctgattcgc ctcgtctcgt caatcaaatt tcttcaattt
       61 agggcagact gcacaatcta tcatcacttt gccgctattg cacgcattgt caggcaaacc
      121 aggcggtcca ggcggcggaa agcggcattg ccagaaggag tgctggaagc atgttgacca
      181 ccgggaacat tttaatgcca cagatgcgta atccggttgc cagcagcaat aaaccgccta
      241 cggcgctgaa gtctgccatc atcgacggtg tggtcagcgg taatatcagc gcggcagccc
      301 acgccagcgt taactggatg atcagtaatg ggatactaat taccgacacc gcaataccca
      361 acgagcaggc gaagatcatc gccgtaaaga aatcgagaaa tgacttggcg attaaaatac
      421 tcgggtcgcc ggtcatccct tcgttcatcg ccccgaagat cccggtgccg ctggcgcaaa
      481 acaggacaat aatcgcgaca taattctgaa taaaagattc atgcgctggc ttcttacgtg
      541 agtggcgaaa cagattttgt gctttggtga ccgcggtatt gacgcctttt tccagcagac
      601 acatttcgcc gattaatgca ccgagtaagg ttgctaaaac catcgccgga aggttggcgc
      661 atttcaccac cagtaaaata ccaatcccca gcgatgccag accaaaaatt gatgtcatgg
      721 agacgcggat acgttccggt aagcgttgac taaggagtgc accgagaacg ccacccagta
      781 atactgcact tgcgttgata aaaggaccga tgaccacaag agttcctgtt agctgcattg
      841 tctgattttc ttattatgaa cgtttggctc cttcgatggc ttgtttgttc gcaaagtcct
      901 ggcttgcacg ctctggtgaa aggtgccatg attgcgcgaa ttttctcctc tctgtacgga
      961 gtttgcccga tgcacgccac ctccttacat tctctcgcta atcgccgttt cgtgcgaaac
     1021 tcctcccttt ttctgctcat gcggtgaagt taacgcacgc tcactgcagg acaacagtaa
     1081 aatcagagcg tttctgcttt tactgatgtc tggcggtcgg agctggtgac cagtttgacc
     1141 catatctcgt ggggcagggt ttttcacctt gtccggtatt cttacttccc cgaaacgggt
     1201 tttgcgctta tgaaatcaat gaatattgcc gccagtagtg aactggtatc ccgactttct
     1261 actcatcgcc gcgtggtggc gttgggagat actgatttta cggacgtcgc ggcagtcgtc
     1321 attaccgctg cggatagtcg cagtggcatt cttgcgttgc ttaagcgcac cggttttcat
     1381 ctaccggtgt ttttgtattc cgaacatgtt gttgaattac ctgcgggcgt tacggcggta
     1441 atcaacggca acgagcagca gtggctggag ctggaatccg cagcctgtca gtatgaagag
     1501 aatttgctgc caccgtttta tggcacgctg acgcagtacg ttgagatggg caacagcact
     1561 tttgcttgcc ctgggcatca acacggtgcg ttctttaaaa agcatcctgc cggacgccat
     1621 ttttacgatt tctttggtga gaacgtcttt cgcgccgata tgtgtaacgc tgatgtaaaa
     1681 ttgggcgatc tgcttattca tgaaggatcg gcgaaggatg cgcagaaatt cgcagccaaa
     1741 gtctttcatg ccgataaaac ctattttgta ctgaacggca catcggcagc gaataaagtg
     1801 gtgacgaatg cgctgttaac gcgtggcgat ctggtgctct tcgaccgtaa caaccataag
     1861 tcgaatcatc acggcgcgct gattcaggcg ggggcgacgc cggtctatct ggaagcttca
     1921 cgtaacccgt ttggtttcat tggcggtatt gatgcgcact gttttaatga agagtatctg
     1981 cgccagcaaa ttcgcgacgt tgcgccagaa aaagccgacc tgccgcgccc gtttcgcctg
     2041 gcgattattc agctgggaac ctatgacggc actgtctata acgcccgtca ggtgatcgat
     2101 accgttgggc atctgtgtga ttacattctg tttgattccg cgtgggtcgg ttacgaacag
     2161 tttatcccga tgatggcgga tagctcgccg ctgctgttag aacttaacga aaacgatccg
     2221 gggatctttg tgacccagtc ggtgcacaaa cagcaggcgg gattctcaca gacgtcgcag
     2281 atccataaaa aagataacca tatccgtgga caggtgcgtt tttgcccgca taagcggttg
     2341 aataatgcct ttatgctcca tgcttctacc agcccgttct atccgctgtt cgccgcgctg
     2401 gacgttaacg ccaaaattca tgaaggggag agtgggcgtc ggctgtgggc ggagtgcgtt
     2461 gcgttgggga ttgaagcccg gaaggcgatt cttgcgcgct gtaagctgtt ccgcccgttt
     2521 atcccgcccg ttgttgatgg caaattgtgg caggattatc cgacgtcagt gttagccagc
     2581 gaccgccgtt ttttcagttt tgagccgggg gcgaagtggc acggctttga aggatatgcc
     2641 gcggatcagt attttgttga tccgtgcaag ctgttactca ccacgccggg tatcgatgct
     2701 gaaaccggcg aatatagcga ctttggcgtt ccggcgacga ttctggcgca ctacctgcgt
     2761 gagaacggca ttgtgccgga gaagtgcgat ctcaactcca ttctgttctt attaactccg
     2821 gcggaaagcc acgagaagct ggcacaactg gtggcgatgc tggcgcagtt tgaacagcat
     2881 attgaggatg actcgccgct ggctgaggtg ttgccgagcg tttataacaa atatccggtg
     2941 cgctatcgcg actacaccct gcgccagttg tgtcaggaga tgcacgatct gtatgtcagt
     3001 ttcgacgtca aagacctaca aaaagcgatg ttccgccagc agagtttccc gtcagtggtg
     3061 atgaatcccc aggatgcgca tagcgcttat attcgcggtg aagtggagtt ggtgcggatt
     3121 cgtgatgccg aagggcgaat tgcggcagaa ggggcgttgc cttatccacc aggcgtgctt
     3181 tgcgtggtac ccggagaagt ctggggtggg gcggttcaac gttatttcct tgcgctggaa
     3241 gaaggggtga atttgttgcc gggattttcg ccggagctgc aaggtgtcta tagcgaaacc
     3301 gatgcagatg gcatgaaacg gttgtacggg tatgtgttga agtaagaata aaaaaacggg
     3361 tcaccttctg gcgacccgtt tttctttgcg taattagtgg ctaaccgtct gtgtgcctgt
     3421 cgggacacga acgtgtttat atttgaacat cgccatgaac gcgaaggcca gaaccacgga
     3481 gtaacctgcg aaaatcagcc atacggtctg ccagtcggta atgccgtttt gggtgtacat
     3541 ctcaaccact ttaccgctca cgatgccgcc gaggatacag ccgaagccgt tagtcatcat
     3601 caggaacatc ccctgcgcac tggcgcgaat tgccgggcta acttcttttt cgacaaacac
     3661 cgaaccagag atgttgaaga agtcgaatgc gcagccgtaa acaatcatcg acagaaccag
     3721 cagtacggtg ccgaacggag tagggtcacc gtaagcaaac agcgcaaaac gcaggatcca
     3781 cgccacgata ctgatcatca ttacgttctt aatgccgtag cggcttaaga agaacgggat
     3841 ggtcagaatg aacagggttt cagagatctg cgaaatcgac atgatgattg acgcatgctg
     3901 cacgatgaag ctgctggcaa acatcggatc tttgtcgaag ctgtgcagga aggtattacc
     3961 gaacatgttg gtaatctgca gttccgcgcc cagcagcatt gagaagatga agaagattgc
     4021 catacgcttg tttttaaaca gcgcgaatgc atcgaggccc agcagggttg tccagctctg
     4081 attcgcttgc tgtttagcaa ccggaatatg cggcagagtc agggtaaaca gaaccagaat
     4141 ggcggaaagt gctgcgccaa tatacagctg catgtggctt aattcgaagc cagacaggct
     4201 caccacccac attgccatga taaagccgat ggtgccccag atacggattg gcgggaagtc
     4261 agtaacgata tccatcccgg cattttgcag gcgatagtaa gagatggtgt tgattaaccc
     4321 aagcgttggc atataagcaa acgagttaat caatatcaca aggaacatcg cttccggcgt
     4381 cgtgacctgt gccgccatga acagcgtgat agcgccaatg gtgtggcaaa tggcatatac
     4441 ccatttcgca cttaaccatt tgtcggccac aatccccagc agcgcaggca taaagaccgc
     4501 ggcgataccc agtgaactat aaactgcgcc aatagaagca ccgtcaaact tcagggtaac
     4561 aaacatatag gagccgaggg tcgtcagcca acttccccac agacagaact gcagaaaaga
     4621 gaggattttc agctgcagct taagattcat gttaatttcc tcacatcgtg atgcggatga
     4681 gtgtttgaaa aagcacattt gaccgtgcga gatgatgcga ttctatcaac ttcgcggact
     4741 ggttttttgt tacctgtggc aaataattgc aaacattccc aatttgcaaa acgaaattgt
     4801 gatgtggata acatttttac ccctgagcat cgtcaggggc ggttagtgga attatcggcg
     4861 gcggtaggat ttttgcgcgg tattcacttt ataaagataa cggcgagatt ccgcagaagg
     4921 atggcgggtc gtcagcgtct gataaacatc gcccggcgtc atggtgttaa taatattggc
     4981 tgcctgaatc ttgtcattcg aaaagactcg cagcacgctg cctgcgccgc cgttataggc
     5041 ggtgatgacg gcataacgcc gggatgtagg gttatcaatt ccgccgagat aaacgttgtt
     5101 cagcatcgcc agatacgcgg tgccggtatc aatattgctg gcaggatcaa acaagaaact
     5161 gcggctcggc gtgccggatt tcccctgcga gcggaacaca tctttcccgg cagtatgttg
     5221 taccacctgc attaatccca gcgcatcgga acggctgact gcatacgggt taaaggaaga
     5281 ttcagtctgc ataattgcca gaatcagcga ctcatcaacg ccatatttgc gtgacgcctg
     5341 gcggaccata ccgagatatt tgtgcgcacg tttatcaagg tggttcggca ccatgttaat
     5401 ggtgacgctg tagatgatac gcagcccgtt gctgcggctc ttcagacggt ttttcagcag
     5461 ataatccgcg aagttgctcg cgcgaccttc ccagcgaatc ggctgcccgg tgttgtccac
     5521 cacctgaccg taaaggaaag gttctttcga aatcgtaata tcatcaacgt cggaatagag
     5581 atcgaccgaa ctcggatcgt cccccatcag caacgttttg attattgccc ggcgcaaatg
     5641 cgcggcaggt tctgtcccgg cgatggtttc gatagtaatc gtaccgtcat cgaagttgat
     5701 gtggctgcgg gtctgatatt gatcggtgta tttcacgtag tccttaggac cggcgatcac
     5761 tacctctttg aatccccaga tgttctcaat attgtgggca aattgcccca tcagaatatc
     5821 aaaaccgttg gtgtctttga cccaggcttc gttataggta tcgccttttt tggtcgtcga
     5881 acaggagatg agcaacggcg caatcaaagc cagcgcgaga tattttttca tcattccggg
     5941 tgcgtgttgt gtttgtttta tgcaagttgc cggaggcgac ctccggcact gtttttattt
     6001 tttgtcttcc ggcgtatagc cctcgatatg cacctcttta ccctcgaaca ggaagttgac
     6061 catctcctgt tccagcagtt tgcggtgctc ggcattcatc atgttgagtt tcttttcatt
     6121 aatcagcatg gtttgtttgt gctgccactg cgcccaggct tctttggaga tctcgttata
     6181 gatgcgtttt cccagttcgc cggggtacag ctgaaaatcc tgaccttctg cttcacgttg
     6241 caggaaagta caaaaaatcg ttctgctcat aaatcatcct ctttatcgac tcacgcgcta
     6301 aaccggcgcg ccagtgcgta actgctgtaa caaacgctcc acgggagccg ccaggccaac
     6361 tgacggcggt tgcgctaagt tataccagag cgcattgcct tcatccatgc agccggtgaa
     6421 tgacgacacg ggaagccaca taggcacaat atctaagtga aaatggctga aggtatggcg
     6481 aaacgcggtc agttgcgtca ggttatcggc agcaatctgc cgttgcgcca gccactgccg
     6541 caaactttct tcgtcggcaa actgtgggaa acagtataaa ccgccccaca atccactcgg
     6601 cgggcgctgc gccagcaata cttcatcttc gtgctgtaac agcagaaagt agccggtgcg
     6661 ctccggcagc gtctgtttcg gttttttgcc cggataaagc gaccagctat tgttggcggc
     6721 ggcaatacat ccgttttgta gcggacagag cgaacatttc ggtttcgagc gcgtacaaat
     6781 catcgcgccc aaatccatca tcgcctgatt aaaccgctcc acgccaaccg cgggcgtcac
     6841 ctgctcgctc aaactccata gtttattctc gacctctttt ttcccaggcc agccgcttac
     6901 agcatagcag cgcgccagca cgcgtttgac gttaccgtcg agaatcggaa agtgcttacc
     6961 cagagaaagc gagagaatcg cgcctgcggt ggaacgcccg acgcccggca gtgctgcaac
     7021 ttcctcaaag gtttccggga atttaccgcc gtgtagggcc gccacttgtt gtgccgcttt
     7081 atgtaggttg cgcgcgcggg cgtaatagcc aagcccggtc cacaagtgga gaacttcgtc
     7141 gagcggcgca ttggcgagat cggtcaccgt tgggaagcgc gccataaagc gttcaaaata
     7201 ggggataacg gtcgcaacct gagtttgttg caacatcact tctgagagcc atactttgta
     7261 gggcgtcttg tcaatttgcc agggcagcgt tttccgcccg tatttatcgt accagtccag
     7321 aacctgggct gaaaattgcg acgcttgcat ggtcaccgaa ttcactgttg ttgggggcaa
     7381 gattgcagca cagcgacggc agggtgtaaa ccggaacttt ccgcagccac ggccttatca
     7441 tgcttgcatc cggcaactaa ctttggataa tgcccgtttt cagaacactt tcacaagcga
     7501 ctaaatcttt atgaaaaacg acgtcatctc accggaattt gatgaaaacg gccgcccgct
     7561 gcgccgtatc cgtagttttg tgcgccgcca ggggcgactg accaaaggcc aggaacatgc
     7621 gttggaaaac tactggccgg tgatgggcgt tgagttcagt gaagatatgc tggatttccc
     7681 cgcgcttttt ggccgtgaag cgccggtgac gcttgagatt ggttttggca tgggggcgtc
     7741 gctggtggca atggctaaag atcgccctga gcaggacttc ctcggcattg aagtgcattc
     7801 accgggcgtt ggtgcgtgcc tggcttctgc gcatgaagag ggcttaagca acctgcgcgt
     7861 gatgtgtcac gatgcggttg aagtgctgca taaaatgatt cctgacaatt cattgcgcat
     7921 ggtgcagctc tttttccctg acccgtggca caaagcgcgc cataataaac gccgtatcgt
     7981 tcaggtgccg tttgccgaac tggtaaaaag caaactgcaa ctggggggcg tattccatat
     8041 ggcgaccgac tgggaacctt atgcggaaca tatgcttgaa gtgatgtctt ctattgacgg
     8101 gtataaaaac ctgtcagaga gcaatgatta cgtaccgcgt ccggcatcac gtccggtgac
     8161 gaaatttgaa caacgtggtc atcgtcttgg tcacggagta tgggacttaa tgttcgagag
     8221 ggtgaaataa tggcaaagaa ccgtagccgt cgtctgcgta aaaaaatgca catcgacgaa
     8281 ttccaggaat taggattttc ggtggcatgg cgattcccgg aaggtacatc ggaagaacag
     8341 attgataaaa ccgttgatga ctttattaac gaggttatcg aaccgaacaa actggccttt
     8401 gacggcagcg gttatatggc ctgggaaggt ctgatctgca tgcaggaaat cggcaaatgc
     8461 accgaagaac atcaggcgat tgtgcgtaag tggctggaag agcgcaaact gggcgaggta
     8521 cgcaccagcg aacttttcga cgtttggtgg gactaagaaa gcatacgggc gatgacaaat
     8581 gcaaaactgc ctgatgtgct acgcttatca ggcctataaa gatgcacgat cgagtaggct
     8641 ggataaggcg tttacgccgc atccggcatg gaaaacgcgc actttgttat caatctgggg
     8701 ccagcaaatg ctggcctgat ttgttcttga gggaagacta tgatgcgcaa aatgctgctg
     8761 gcggcagcac tttcagtgac ggcaatgacc gctcacgccg actaccagtg cagcgtcacg
     8821 ccgcgtgacg atgtgattgt cagcccgcag accgtgcagg tgaagggcga aaacggcaat
     8881 ctggtgatca cgccagacgg caacgtgatg tataacggta agcaatattc cctgaatgcc
     8941 gcccagcgcg agcaggcgaa ggattatcag gctgaactcc gtagcaccct gccgtggatt
     9001 gatgaaggcg cgaaaagccg cgtcgaaaaa gcccgtattg cgctggataa aattatcgtt
     9061 caggagatgg gcgaaagcag caaaatgcgc agccgtctga ccaaacttga tgcgcagctg
     9121 aaagagcaga tgaaccgcat tatcgaaacg cgcagcgatg gcctgacgtt ccactataaa
     9181 gccattgatc aggttcgcgc cgaaggccag caattagtga atcaggcaat gggcggaatt
     9241 ttacaggaca gcattaatga aatgggcgcg aaagcggtgc tgaaaagcgg cggtaaccca
     9301 ttacagaacg tgctgggaag cctgggcggt ctgcaatcct caatccaaac cgagtggaaa
     9361 aagcaggaaa aagatttcca gcagtttggc aaagatgttt gtagccgcgt tgtgactctg
     9421 gaagatagcc gcaaagccct ggtcgggaat ttaaaataat cctctatttt aagacggcat
     9481 aatacttttt tatgccgttt aattcttcgt tttgttacct gcctctaact ttgtagatct
     9541 ccaaaatata ttcacgttgt aaattgttta acgtcaaatt tcccatgcaa agctaaggga
     9601 taatgcgtag cgttcacgta actggaggaa tgaaatggag tttttcaaaa agacggcact
     9661 tgccgcactg gttatgggtt ttagtggtgc agcattggca ttacccaata tcaccatttt
     9721 agcaaccggc gggaccattg ccggtggtgg tgactccgca accaaatcta actacacagc
     9781 gggtaaagtt ggcgtagaaa atctggttaa tgcggtgccg caactgaagg acattgcgaa
     9841 cgttaaaggc gagcaggtag tgaatattgg ctcccaggac atgaacgatg atgtctggct
     9901 gacactggcg aaaaaaatta acaccgactg cgataaaact gacggcttcg tcattaccca
     9961 cggtaccgac acgatggaag aaaccgctta cttcctcgac ctgacggtga aatgcgacaa
    10021 accggtggtg atggtcggtg caatgcgccc gtccacgtct atgagcgcag acggtccatt
    10081 caacctgtat aacgcggtag tgaccgcagc tgataaagcc tccgctaatc gtggcgtact
    10141 ggtagtgatg aatgacaccg tgcttgatgg ccgtgatgtc accaaaacca acaccaccga
    10201 tgtagcgacc ttcaagtctg ttaactacgg tcctctgggt tacattcaca acggtaagat
    10261 tgactaccaa cgtaccccgg cacgtaagca caccagcgac acgccgttcg atgtctctaa
    10321 gctgaatgaa ctgccgaaag tcggcattgt ttataactac gctaacgcat ccgatcttcc
    10381 ggctaaagca ctggtagatg cgggctatga tggcatcgtt agcgctggcg tgggtaacgg
    10441 caacctgtat aaaaccgtat ttgacaccct tgcaaccgct gcgaaaaacg gcactgcagt
    10501 agtgcgttct tcccgcgtac cgacgggcgc taccactcag gatgccgaag tggatgatgc
    10561 gaaatacggc ttcgtcgcct ctggcacgtt gaacccgcaa aaagcgcgcg ttctgctgca
    10621 actggctctg acgcaaacta aagatccgca gcagatccag cagatcttca atcagtacta
    10681 atcacttcgc cccggtatcg tgccggggct tattcacttc agactcacgt ccattgccaa
    10741 tttttattac cctaatgata atcaccagaa taaattattc cgcgcgaggg ttttcgggtg
    10801 aaaaagcaat ggattgttgg tacggcgctg cttatgttga tgactggtaa tgtccgggca
    10861 gatggtgaac cgccaactga aaatatctta aaagatcaat tcaaaaagca gtatcacggc
    10921 attctcaagc ttgatgtcat caccttaaaa aatcttgatg ctaagggtaa tcaggccacc
    10981 tggtcagcgg aaggcgatgt ctcttccagt gacgatctct atacctgggt cggtcagttg
    11041 gcagattacg agctgctcga acagacctgg acgaaagata aaccggtgaa attctcggcg
    11101 atgttaacca gtaaaggaac gcccgcgtct ggctggtcgg tgaactttta ctcttttcag
    11161 gcggcagcca gcgatcgtgg gcgggtggtt gacgatatca aaaccaataa taaatatctg
    11221 atcgtgaata gcgaagattt caattatcgc tttagtcagc ttgagtctgc attgaataac
    11281 cagaataact cgattcctgc actgaaaaag gatgtaaaag cgcttgataa gcaaatggtg
    11341 gcggcgcaga aagcagcgga tgcatattgg ggaaaagatg caaacggtaa gcaaatgacc
    11401 cgcgaagacg cctttaaaaa aattcaccaa cagcgtgatg attttaataa acagaacgat
    11461 agtgaggcgt tcgcggttaa atatgacaaa gaggtttatc aaccggcgat tgcggcatgt
    11521 cataaacaga gtgaagagtg ttatgaagtg ccaattcagc agaaacgaga ttttgatatc
    11581 aacgaacaac ggcgacagac ttttctgcaa tcacaaaaac ttagccgtaa attgcaggat
    11641 gactggataa cgctcgaaaa agggcaatat ccgttaacga tgaaagtttc agaaataaac
    11701 agtaaaaaag tcacgatttt gatgaaaatt gacgatatca actaggttta tgaacgctgg
    11761 aaaaaagata ccgaacaatt gcggcgcaat ggggtgatta agtaattttt gcgatgacgc
    11821 aagagttgta gccggatgtt gcgtacacgc cgcatccggc aatacaaatt tactcagcca
    11881 gaaaaagctc cagcagcgaa tttaaaaaca acttcccatg ttccgttatc tgccagtaat
    11941 ccgcacattc tgtgagataa ccctgagcga tagcctcgtc taactgaggg cgaataacct
    12001 cttctgaaag gccagtatac tggctaaact ccacgcgcgg cgcggcttcc agcaaacgga
    12061 agcgattcat aaagaactca aacggtttat ctgcggcttc gacatcacgc tggctttcca
    12121 gataccgccc ctgcataaaa ccacgtggat gacgcgtttt ggtggtacgc agaatgcgcc
    12181 catccgggaa ggtcactttg ccatgcgcgc cgcagccaat accgatgtag tcaccaaagc
    12241 gccagtagtt gagattgtgc tggcactgat aaccgggttt ggcgtaagcg gaagtttcat
    12301 attgctgata acccgctgcg gttaataact gatgcccctg ttcgaaaatg tcccacagcg
    12361 cgtcatcgtc cggcagtaca ggagggcgcg aaccaaacag cgtattgggt tcgatggtca
    12421 gttgatacca ggaaagatgc ggcggattca gttcaatggc ctggcgtaga tcgcctagcg
    12481 cctcttccag tgattgatcc ggtagcccat gcatcaaatc gaggttaaag ctacgtaacc
    12541 ctaaaccgct cgccagattt gccgctcgtt tcgcttcttg cgggccatga atgcgcccaa
    12601 gtcgtttcag cttttcttcg ctaaaactct gtacgccaat ggagatgcgg ttcacaccag
    12661 cacgctgata atcaacaaag cgatcggctt caaccgtacc agggttcgct tccatcgtaa
    12721 tttctgcatc cgctgccagc ggcaaacgcg cacgtacgcc gttcagcagc gtttgcatcg
    12781 ccgggccgga aagcaggctc ggcgtaccac cgccaataaa gattgtcttt acttcacggc
    12841 cctgagcgta agccacatcg ttgtccagat cgttaagcag atgctgaaca taatcgtcgt
    12901 gcggcacttc tcctttcaac gcgtgagagt tgaaatcgca gtacgggcat ttctgcacgc
    12961 accacgggat gtgaatgtag agactcagcg gcggtaattt aaccattacg taaagcgtcc
    13021 agcagcagtt tcaacgcctg accacggtgg gaaatggcgc tcttttcttc gcgggtcagt
    13081 tcggcagcag ttttcccttc ggaaggtacg aagaagattg gatcataacc aaagccacca
    13141 gtgcccgctg gttcacgagt aatcacgccc ggccagctgc cgtggcacac cagcggagta
    13201 ggatcttccg cgtgacgcag atataccagc acgcagtgga aacgcgcctg acgttggtcg
    13261 tccggtacgt ctttcattgt ttccagcagt ttttgcagat tcttttgatc ggtcgcgtct
    13321 tcaccggaat aacgcgcgga gtaaataccc ggcgcgccac ccagcgcatc taccgccaga
    13381 ccggagtcgt cggcaattgc cggtaaaccg gtcacttttg ccgcatggcg cgctttcaga
    13441 atcgcgtttt cgataaaggt caggccggtt tcttcagcgg aatctacgcc gaggtctgtt
    13501 tgggcaacga tatcaagacc gaagtcgcta agcagcgacg ccagctcacg cactttaccg
    13561 gcattgccgg ttgcgaggac aactttttgc ataggatacc taattaatta acgccgcgat
    13621 ttctggcggg atttgttgcg gattaatgat tttaatttgt ttgtggcggc caagttcgcc
    13681 tttttcaatc accacctggc ttttggcaac ccggaattgc ttaccgagaa acttcaccag
    13741 atggctgttg gcctggccgt caaccggcgg cgcggtaatg gcgactttta cctcgtcgcc
    13801 atgtaaaccg acaatagaat cacggctggc tttcggctga atatagagcc gtaaaaccag
    13861 accgtcatca ttaactgtta cggcactcat aacgccatcc acagccccgg cagcagcata
    13921 tttccggtcg cctgcaagac ttctgcgaca cccatattga tgacatacag cagcagaacg
    13981 aggatcatcg gcgagaaatc aatcccaccc attgccggta gcaagcggcg aatcgggcgc
    14041 agcagcggat cggccagctg aatcagcacg tattcaatcg ggctacgacc ctggcttacc
    14101 cagctcataa tcgccatcac cagcaggacc cagaaaatca gcaggccgat ggttttcagc
    14161 agaatcaata aaccggcaat ccaaatgatt ggcaggaagg tcaccacttt aaacagcacg
    14221 atggctttaa tgaaactgag aatataggca accagcagcg aggcgctatc aatggggccc
    14281 attgccggaa taacgcggcg cagtggcccg ataatcggct gcgttacctt cactacaaac
    14341 tgtgagaagg ggttgtaaaa atcacaatga gcccactgca tccagatgcg taataacagc
    14401 accatggtat acagctcaat gaccgttgaa agcaggaaag tcaacgtatt catggcgttc
    14461 ctttaattcc ttatttttta gagtaatcac gcgcaccaaa aattgcagtg ccgatacgaa
    14521 ccatcgtgct acctgccgca atggcggctt ccatatcgtc cgacattccc agagagagcg
    14581 tgtcgatatg cgggtagcgc gttttcagtc cggcaaatgc tacagccatt tggcgtgcaa
    14641 cttcaaactg ccttacatat tctgactcag gcgcagggat tgccatcagc ccgcgcagac
    14701 gtaaacgcgg tagttcagcg accgcagctg ccagctcgtc cagttcagcc agttgaatcc
    14761 cggacttact gttttcatca ctaatgttaa tttgaatcag tacgttaaga gggggaagtt
    14821 ctgccgggcg ctggtcgttc agacgggtag cgatgcgcaa acggtcgatg gtatgacacc
    14881 agtcgaaatg ctctgccacc aggcggcttt tattagactg caacgggcca ataaaatgcc
    14941 attctaatcc tgttacgctc agttcctgaa agtggcgaat tttatctacc ccttcctgaa
    15001 cgtagttttc accaaattga cgctgcccgg catcaatggc ttctgcgatg gcgctcgcag
    15061 gttttgtttt actgactgca agcagcgtaa tttcttctgg agaacggccg caacgcgttg
    15121 cagccgctga gattttgtcc cggacctgtg ccaggttatg cgcaatatcg ttcattttcc
    15181 gaggatctta gtatgaatat ggaagaaatt gtggccctta gtgtaaagca taacgtctcg
    15241 gatctacacc tgtgcagcgc ctggcccgca cgatggcgta ttcgcgggag aatggaagct
    15301 gcgccgtttg acgcgccgga cgtcgaagag ctactgcggg agtggctgga tgacgatcag
    15361 cgggcaatat tgctggagaa tggtcagctg gattttgctg tgtcgctggc ggaaaaccag
    15421 cgattgcgcg gcagtgcgtt cgcacaacgg caaggtattt ctctggcgtt acggctgtta
    15481 ccttcgcact gcccgcagct cgaacagctt ggcgcaccac cggtattgcc ggaattactc
    15541 aagagcgaga atggcctgat tctggtgacg ggggcgacgg ggagcggcaa atctaccacg
    15601 ctggcggcga tggttggcta tctcaatcaa catgccgatg cgcatattct gacgctggaa
    15661 gatcctgtgg aatatctcta taccagtcag cgatgtttga tccaacagcg ggagattggt
    15721 ttgcactgta tgactttcgc atcgggattg cgggctgcat tgcgggaaga tcctgatgtg
    15781 attttgctcg gagagctgcg tgatagcgag acaatccgtc tggcgctgac ggcggcagaa
    15841 accgggcatc tggtgctggc gacattacac acgcgcggcg cagcgcaggc agttgagcga
    15901 ctggtggatt cgtttccggc gcaggaaaaa gatcccgtgc gtaatcaact ggcaggtagt
    15961 ttacgggcgg ggttgtcaca aaagctggaa gtggataaac aggaaggacg cgtggcgctg
    16021 tttgaattac tgattaacac acccgcggtg gggaatttga ttcgtgaagg gaaaacccac
    16081 cagttaccgc atgttattca aaccgggcag caggtgggga tgataacgtt tcagcagagt
    16141 tatcagcagc gggtgaaaga agggcgcttg tgacgttgct gtgtctgata cgaattgtaa
    16201 atatgcccga tgcgcaagct tatcgggcct acaagggaag cgtaactttg aattcgcact
    16261 cactgtaggt tggataaggc gtttacgccg catccaacat gaaacaacga gcacattgtc
    16321 agaaatctgt gcgctagtaa atcgccttaa tatccctgct cgaaatagct ttcgagaata
    16381 ataaccgcag aggcagagtc gactttgcct ttgttgagcg cccgatagcc gccctgttca
    16441 aacagaccgg aacgtgcctc cacggtgcta agacgctcgt catggagctt tacttcaaca
    16501 ccgaaacgac catgaatacg gttggcaaat ttacgcgctc tggcggttaa cggctgttcg
    16561 gtgccgtcca tattcagcgg caaaccgacg atgatttcgt ccggctgcca ctctttcagt
    16621 aaacgctcga taatgttcca gtccggcgta ccgtcctgcg ctttaattgc aggcaaaggg
    16681 cgagcggtgc cggtaatgcg ttggccgacc gctacgccaa tgcttttggt gccgaagtcg
    16741 aaggcgagta aggttccact catcaggcgt gtcctgccac accaggcatg gtgagaatat
    16801 ccacaccaat cagttttgcc gcctcgcgcc agcggtccgc aatcggcgtt ttgaacagaa
    16861 tattcagatc tgccggggcg gttagccacg cgttatcgag aatttcttgt tccagttgac
    16921 ctttctccca ggaggcatag cccagagcca ccaatacgtc agacggttgt ttatcggtgc
    16981 cgagcgtttc cagcacatcg cgggaagtgg tcatcaccgt gttgtctgaa atgcgaatgc
    17041 tggaagcaaa attggagggc ggagtatgca aaataaaccc gcgatcttca gccagtgggc
    17101 cgccgagcat aaccggttta tccagacgga ttgattcatc acgcggctcc ggcgtgatct
    17161 tcagtttttc cagaatccct tcaattttga gattttccag cggcttgttg acgatgatcc
    17221 ccattgcacc attggtatta tgttcgcaaa tgtagaccac ggaacgacgg aaaatcggat
    17281 cctggagagc aggcatggca ataagaaagt gatgctgtaa attcattgtc agaggttctg
    17341 tttcctggtt caaaaaagca acagcgccca gtatgcgtgg aaagaagggc gctgtcactc
    17401 agagtctcaa cgagatcctt ctcgctaagg tgggttactg ctgctgtaaa cgtgcttcga
    17461 tggcatccat taacattccg gtgatcgaca ccggaaattc tgcttcaatc tcacgaatac
    17521 aggttgggct ggtgacgtta atttcagtca gacggtcgcc gatgatatcc agaccaacaa
    17581 aaatcagccc tttttctttc agcgtcggcc caatctgacg ggcgattttc cagtcacttt
    17641 ccgtcagcgg acgaggttca ccgcgaccac cggcagccag attgccacgg gtttcgcccc
    17701 cctgcggaat acgcgccagg caatacggca ccggctcgcc atccactacc agcacgcgtt
    17761 tgtcgccatc tttaatggct ggcaggtaat tttgcgccat gcagtagcga gtgccatgct
    17821 cagtcagggt ttcggcaatc acgccgaggt ttggatcgcc ttctttcacg cggaaaatcg
    17881 acgcgccgcc cataccgtcc agtggcttaa gaatgatgtc gctgtgtttc tcccagaacg
    17941 cttttagctg cgctttattg cgcgtaacca gcgtttctgg cgttaagtca gagaaccagg
    18001 cagtaaacag tttctcgtta cagtcgcgca ggctctgcgg cttgttaacg atcagcgtcc
    18061 ctttctcttc ggcacgttcc agaatatagg tcgcgtagat aaactcggta tcaaacggcg
    18121 ggtctttacg catcaggatc acatcgagat cggccagcgg cagatcctgt tcaccgacga
    18181 acgaaaacca ctcttcgtag ttctgcttca cgttcagcgt gcgggtatgg gcgcgggctt
    18241 cgccattgat cagatacaga tcgcccatct ccatatagtg aagttcgtaa ccacgacgct
    18301 gtgcttccag caacatagcg aaactggaat ctttcttgat gttgatgttt gcgatggggt
    18361 ccatcacgat gccgagcttg atcattattc ttctccgtta gcccaaatcg ccaaatcgta
    18421 cttgtagcgc ggtaatggcg gtgagcgcag ttgtctctgt acgcaaaacg cgaggtccca
    18481 acaggatatc agtaaattga tagcgggcag tcatggcaat ttcatctgcc gataaaccgc
    18541 cttccgggcc aatcagcagg cggacgcgtt caaccggtaa cggcaacgtg ttgatgctgt
    18601 tactggcgcg cgggtgaaga ttcagtttca gtccttcatc ctgctctgca caccaggctt
    18661 ccagatccat cgctggacgg atttccggca cccggttacg accacactgc tcacaggcag
    18721 caattgcaat cttctgccac tgctggagct tcttgttcag acgttcacta tccagtttaa
    18781 cgccgcagcg ttcagaaaaa agtggcgtaa tgaggcttac accgagttcg atcgatttct
    18841 ggatagtaaa ttccattttt tcgccacgcg acatcacctg accgaggtga atatgcagcg
    18901 gagattcacg atcgtcgagt tggccttcca gcactttcac ttccacgctt tttttactgg
    18961 cgctggtaat ttcggcgtca aagacctggt tgctgccgtc aaacaattgc aacgcctgtc
    19021 ccggccccat gcgcagtacg cgcccgatat ggttggcggc atcttcgcaa agcgcgatgt
    19081 gagaatggct ggttagtggt tcaggatgat aaatgcgggg gatacgcata gttaaaaatc
    19141 cgcgtcgtct ccccacgcgg ttgtacgcgt ggggtagggg ttaacaaaaa gaatcccgct
    19201 agtgtaggtt agctctttcg cgcctggcaa gcgcgttgca catacgggtt atgattgccc
    19261 tgcaccttcg cgatgcgttc atcgcgctcg cactcccagt cggtaaccgg atacatcttg
    19321 ttccatgcgt tgaacagctg cgtttgctgg cgggagagtg tcaggttgta ttggtcgcgc
    19381 atatagaagt aggtgcgcgc aatggcaccg cgtgcacgcg ctggtggttc ggcagctttt
    19441 tctttgaaat cgaccttcat ggcgcattga ccgtactggc cttcgccgcc attccactgg
    19501 ctgtacataa agttgccgcg atcgccattc acctcgccga ctgacggctg caggttatgc
    19561 atatcgcttt ccatcttgcg atagaccgga tctttggcgc aatttttacg tccaccgtcc
    19621 tgccagcact ggcgctggtg accgaattgc caggcgggaa ggacgtgttc ccactctacg
    19681 cggctggcgc ggttttcatt tttgcgcacc tgatagccgc acgattgcag atcaacaacg
    19741 ccttttttgc cctgccagtt aattttacat ccgcaataaa acgtaccggg cgcgtcagcg
    19801 tggactttta ccgccgcggc tttcgcctga gaaaaactat tgataccttc ggccaacgcc
    19861 gggccggaaa atgctgcgct cagtaccacc gcagcaatag acaaataacg gtacatcact
    19921 tactccgtgt taaaacgagc cagcaacgta gcgaaagttg ttttagtatg caatcagcca
    19981 gatcaggaaa gttcctgata gttcaggtgg ttactttgca accagctgtt cgccgcagtg
    20041 aacacagcga tagacggctt cgccacgaac tacgcgatta tgacggcgta cggtaagctg
    20101 atgctcctgg cacttgcagc ggtaggggaa ggtgttgcgg cgcacggatt gcagttcgaa
    20161 ctgatgcgta cggcgggcgg gaacgcccag cacgctttcc atcatccact tccactcttt
    20221 gccatgtggc gctacgcggc cgaaatgttt ccataccagc aaatgtgcca gttcgtgcgg
    20281 caccacttct tcaataaagg cttcactgtt ttccaacagc aaaacgggat tgaggcggat
    20341 ttcatagctt tccagccagg ctgttccggc ggaggtgccg cgctgggtgt aagagagttt
    20401 tggctccggg tagttacgcc ctagcttcag gttggcctgg gcgagttttt cccgcaggcg
    20461 acgcataacg gcctgttgga tggcgatagg gagacgggat gttttcatag cggcagagga
    20521 tagagcgaag aaaagatgac tgcaagaggt ggcttcctcc gcgacgggag gaagcctgag
    20581 gagattaatc gtgagcgccg atttcgcgca gtttacgacc tttcatcaga ttacgttcaa
    20641 tatgttccag cgaaacgtgt ttggtttccg gtaccagcca caatgtcagc aggataaaca
    20701 gtacgttcag agccgcgtac acccagaagg tgttggcgtt acccagcgtg ttgagcatgg
    20761 tcaggaacgt tgcgccaacg atcatgttgg caatccagtt ggtggcggtg gagcaggtga
    20821 tgccaaaatc gcggcctttc agcggctgaa tttcggagca cagtacccaa atcagcggac
    20881 cggcactcat ggcaaaaccg acaataaaca tcagcagcat ggcgatggcg aaatactgcg
    20941 ccgacggaga gtggataccg atatgcatca ttgtaccgag tacgcccata ccagcagcca
    21001 tcaccaggaa gcccagcgtt agcgttggtt tacgtcccca gcggtcaaca aggccgattg
    21061 cgataaaggt ggcaagtacg ttggtcaggc cgacaatcac tgtcccccac atttgctcgg
    21121 tggtgttggt ataacccgcc agttcgaaga ttttcggcgc gtaatacatg atgacgttca
    21181 tcccggtgaa ttgctgcatt acctgtaaca gtacgccaag gaacaccgcg cggcggaagt
    21241 tgctattctc tttaaacagc gcccagccac tctgtttaac ctgcaaactt tcacggattt
    21301 catccagttc gcgtttcgct tccgcgctgg tgtcacgcag gcgtagcagc acgcgttcgg
    21361 catcaacaaa acggcgtttg gcggcaaacc aacgtgggct gtctggcagg aagaagacac
    21421 caatcagcag caaaattgcc gggatgataa tcacacccag catccagcgc catgcaccgg
    21481 tgtagctgaa ggcggtatca gaaagataag caccgaggat cccgatagtg atcatcaact
    21541 gatacataga gatcatactg ccgcgaattt tttccggcgc aatttcagag aggtacagtg
    21601 gtgcggtata agaggccaca cccaccgcca gccccagcag aacgcgggaa agaatcagta
    21661 cttcaacgtt tggcgcagcc gcagagaaca gcgaaccggc aacaaacaaa attgcgccga
    21721 tcatcaggct ctttttgcgc ccgagtttaa aggagagcca gccgctgccc accgcaccga
    21781 ctgccgcacc gaacatcatg gagcttacga cccattcttg cgtgtgcgaa gtaatctgga
    21841 attcatctgc aataaacggc agtgcgccag caattacacc gatatccagg ccaaagagta
    21901 atcccgccag agcggcaagg aagcagacga aaaacgtcat tgccttgttt gaccgcccct
    21961 gttttttagc gtcaggcatg atgccctcca atatggttat tttttattgt gaattaagat
    22021 aggtgagtac gacgtaaaa
//
LOCUS       DACAOP010000078        21993 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.078, whole genome shotgun sequence.
ACCESSION   DACAOP010000078 DACAOP010000000
VERSION     DACAOP010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21993
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.078"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..278)
                     /locus_tag="IT892_003213"
     CDS             complement(<1..278)
                     /locus_tag="IT892_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HAP3136399.1"
                     /translation="MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILL
                     GPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRH"
     gene            complement(598..2016)
                     /gene="dhaM"
                     /locus_tag="IT892_003214"
     CDS             complement(598..2016)
                     /gene="dhaM"
                     /locus_tag="IT892_003214"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415716.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaM"
                     /protein_id="HAP3136400.1"
                     /translation="MVNLVIVSHSSRLGEGVGELARQMLMSDSCKIAIAAGIDDPQNP
                     IGTDAVKVMEAIESVADADHVLVMMDMGSALLSAETALELLAPEIAAKVRLCAAPLVE
                     GTLAATVSAASGADIDKVIFDAMHALEAKREQLGLPSSDTEISDTCPAYDEEARSLAV
                     VIKNRNGLHVRPASRLVYTLSTFNADMLLEKNGKCVTPESINQIALLQVRYNDTLRLI
                     AKGPEAEEALIAFRQLAEDNFGETEEVAPPTLRPVPPVSGKAFYYQPVLCTVQAKSTL
                     TVEEEQDRLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSGHHTLLDDPELLAAASEL
                     LQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTKEELPQ
                     FNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPVSHSALIARELGIGWICQQGEKL
                     YAIQPEETLTLDVKTQRFNRQG"
     gene            complement(2027..2659)
                     /gene="dhaL"
                     /locus_tag="IT892_003215"
     CDS             complement(2027..2659)
                     /gene="dhaL"
                     /locus_tag="IT892_003215"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase ADP-binding subunit
                     DhaL"
                     /protein_id="HAP3136401.1"
                     /translation="MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNR
                     GFSKVVEKLPAIADKDIGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQATQARQSLT
                     LEELYQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPVALEAASS
                     IAESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE"
     gene            complement(2670..3740)
                     /gene="dhaK"
                     /locus_tag="IT892_003216"
     CDS             complement(2670..3740)
                     /gene="dhaK"
                     /locus_tag="IT892_003216"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415718.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAP3136402.1"
                     /translation="MKKLINDVQDVLDEQLAGLAKAHPSLTLHQDPVYVTRADAPVAG
                     KVALLSGGGSGHEPMHCGYIGQGMLSGACPGEIFTSPTPDKIFECAMQVDGGEGVLLI
                     IKNYTGDILNFETATELLHDSGVKVTTVVIDDDVAVKDSLYTAGRRGVANTVLIEKLV
                     GAAAERGDSLDACAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIH
                     GEPGIDRRPFSSLDQTVDEMFDTLLVNGSYHRTLRFWDYQQGSWQEEQQTKQPLQSGD
                     RVIALVNNLGATPLSELYGVYNRLTTRCQQAGLTIERNLIGAYCTSLDMTGFSITLLK
                     VDDETLALWDAPVHTPALNWGK"
     gene            3959..5887
                     /gene="dhaR"
                     /locus_tag="IT892_003217"
     CDS             3959..5887
                     /gene="dhaR"
                     /locus_tag="IT892_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase operon
                     transcriptional regulator DhaR"
                     /protein_id="HAP3136403.1"
                     /translation="MRDMSGAFNNDGRGISPLIATSWERCNKLMKRETWNVPHQAQGV
                     TFASIYRRKKAMLTLGQAALEDAWEYMAPRECALFILDETACILSRNGDPQTLQQLSA
                     LGFNDGTYCAEGIIGTCALSLAAISGQAVKTMADQHFKQVLWNWAFCATPLFDSKGRL
                     TGTIALACPVEQTTAADLPLTLAIAREVGNLLLTDSLLAETNRHLNQLNALLESMDDG
                     VISWDEQGNLQFINAQAARVLRLDATASQGRAITELLTLPAVLQQAIKQAHPLKHVEA
                     TFESQHQFIDAVITLKPIIETQGTSFILLLHPVEQMRQLMTSQLGKVSHTFAHMPQDD
                     PQTRRLIHFGRQAARSSFPVLLCGEEGVGKALLSQAIHNESERAAGPYIAVNCELYGD
                     AALAEEFIGGDRTDNENGRLSRLELAHGGTLFLEKIEYLAVELQSALLQVIKQGVITR
                     LDARRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYALHAFEITIPPLRMRRGSIPAL
                     VNNKLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELYSVIENLALSSDNGRIRVSD
                     LPEHLFTEQATDDVSATRLSTSLSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTL
                     WRKMKQHGIDAGQFKRRV"
     gene            complement(5987..8854)
                     /locus_tag="IT892_003218"
     CDS             complement(5987..8854)
                     /locus_tag="IT892_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HAP3136404.1"
                     /translation="MGIKQHNGNTKADRLAELKIRSPSIQLIKFGAIGLNAIIFSPLL
                     IAADTGSQYGTNITINDGDRITGDTADPSGNLYGVMTPAGNTPGNINLGNDVTVNVND
                     ASGYAKGIIIQGKNSSLTANRLTVDVVGQTSAIGINLIGDYTHADLGTGSTIKSNDDG
                     IIIGHSSTLTATQFTIENSNGIGLTINDYGTSVDLGSGSKITTDGSTGVYIGGLNGNN
                     ANGAARFTATDLTIDVQGYSAMGINVQKNSVVDLGTNSTIKTNGDNAHGLWSFGQVSA
                     NALTVDVTGAAANGVEVRGGTTTIGADSHISSAQGGGLVTSGSDAIINFTGTAAQRNS
                     IFSGGSYGASAQTATAVVNMQNTDITVDRNGSLALGLWALSGGRITGDSLAITGAAGA
                     RGIYAMTNSQIDLTSDLVIDMSTPDQMAIATQHDDGYAASRINASGRMLINGSVLSKG
                     GLINLDMHPGSVWTGSSLSDNVNGGKLDVAMNNSVWNVTSNSNLDTLALSHSTVDFAS
                     HGSTAGTFATLNVENLSGNSTFIMRADVVGEGNGVNNKGDLLNISGSSAGNHVLAIRN
                     QGSEATTGNEVLTVVKTTDGAASFSASSQVELGGYLYDVRKNGTNWELYASGTVPEPT
                     PNPEPTPAPAQPPIVNPDPTPEPAPTPKPTTTADAGGNYLNVGYLLNYVENRTLMQRM
                     GDLRNQSKDGNIWLRSYGGSLDSFASGKLSGFDMGYSGIQFGGDKRLSDVMPLYVGLY
                     IGSTHASPDYSGGDGTARSDYMGMYASYMAQNGFYSDLVIKASRQKNSFHVLDSQNNG
                     VNANGTANGMSISLEAGQRFNLSPTGYGFYIEPQTQLTYSHQNEMTMKASNGLNIHLN
                     HYESLLGRASMILGYDITAGNSQLNVYVKTGAIREFSGDTEYLLNNSREKYSFKGNGW
                     NNGVGVSAQYNKQHTFYLEADYTQGNLFDQKQVNGGYRFSF"
     gene            complement(9623..10714)
                     /gene="ychF"
                     /locus_tag="IT892_003219"
     CDS             complement(9623..10714)
                     /gene="ychF"
                     /locus_tag="IT892_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAP3136405.1"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVV
                     PMPDPRLDQLAEIVKPQRTLPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGH
                     VVRCFENDNIIHVSGKVNPADDIEVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
                     ELAVLEKCLPQLENAGMLRALDLSAEEKAAIRYLSFLTLKPTMYIANVNEDGFENNPY
                     LDQVREIAAKEGSVVVPVCAAVEADIAELDDEERDEFMQELGLEEPGLNRVIRAGYKL
                     LNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTISFEDFITYKGEQ
                     GAKEAGKMRAEGKDYIVKDGDVMNFLFNV"
     gene            complement(10831..11415)
                     /gene="pth"
                     /locus_tag="IT892_003220"
     CDS             complement(10831..11415)
                     /gene="pth"
                     /locus_tag="IT892_003220"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAP3136406.1"
                     /translation="MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAK
                     FFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGV
                     AKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQK
                     LIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ"
     gene            11693..11971
                     /gene="ychH"
                     /locus_tag="IT892_003221"
     CDS             11693..11971
                     /gene="ychH"
                     /locus_tag="IT892_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein YchH"
                     /protein_id="HAP3136407.1"
                     /translation="MKRKNASLLGNVLMGLGLVVMVVGVGYSILNQLPQFNMPQYFAH
                     GAVLSIFVGAILWLAGARVGGHEQVCDRYWWVRHYDKRCRRSDNRRHS"
     gene            complement(12026..13705)
                     /gene="dauA"
                     /locus_tag="IT892_003222"
     CDS             complement(12026..13705)
                     /gene="dauA"
                     /locus_tag="IT892_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylic acid transporter DauA"
                     /protein_id="HAP3136408.1"
                     /translation="MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAI
                     PLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGL
                     AGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
                     AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCA
                     VMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIR
                     TLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATA
                     AIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSE
                     AHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAP
                     VVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAF
                     QRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL"
     gene            complement(13830..14777)
                     /locus_tag="IT892_003223"
     CDS             complement(13830..14777)
                     /locus_tag="IT892_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HAP3136409.1"
                     /translation="MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQI
                     NENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVR
                     SARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
                     LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVL
                     VDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP
                     LSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH"
     gene            complement(14928..15779)
                     /gene="ispE"
                     /locus_tag="IT892_003224"
     CDS             complement(14928..15779)
                     /gene="ispE"
                     /locus_tag="IT892_003224"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAP3136410.1"
                     /translation="MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIE
                     LRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGG
                     GLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEIL
                     TPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKR
                     FREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGANLS
                     PLHRAML"
     gene            complement(15779..16402)
                     /gene="lolB"
                     /locus_tag="IT892_003225"
     CDS             complement(15779..16402)
                     /gene="lolB"
                     /locus_tag="IT892_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein localization protein LolB"
                     /protein_id="HAP3136411.1"
                     /translation="MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQ
                     DVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGN
                     VQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEI
                     TYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK"
     gene            16616..17872
                     /gene="hemA"
                     /locus_tag="IT892_003226"
     CDS             16616..17872
                     /gene="hemA"
                     /locus_tag="IT892_003226"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HAP3136412.1"
                     /translation="MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGG
                     VVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMR
                     VASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGA
                     SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRER
                     AQILADEVGAEVIALSDIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLL
                     VDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMA
                     WLRAQSASETIREYRSQAEQVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAP
                     TKSLQQAARDGDNERLNILRDSLGLE"
     gene            17914..18996
                     /gene="prfA"
                     /locus_tag="IT892_003227"
     CDS             17914..18996
                     /gene="prfA"
                     /locus_tag="IT892_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAP3136413.1"
                     /translation="MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQ
                     LSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLP
                     KDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYK
                     EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDIN
                     PADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGA
                     RIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVME
                     GKLDMLIEPIIQEHQADQLAALSEQE"
     gene            18996..19829
                     /gene="prmC"
                     /locus_tag="IT892_003228"
     CDS             18996..19829
                     /gene="prmC"
                     /locus_tag="IT892_003228"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAP3136414.1"
                     /translation="MEYQHWLREAISQLQASESPRRDAEILLEHVTGRGRTFILAFGE
                     TQLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSLPLFVSPATLIPRPDTECLVEQA
                     LARLPEQPCRILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAIKN
                     IHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDVRFEPLTALVAADSGMADIV
                     HIIEQSRNALVSGGFLLLEHGWQQGEAVRQAFILAGYHDVETCRDYGDNERVTLGRYY
                     Q"
     gene            19826..20218
                     /locus_tag="IT892_003229"
     CDS             19826..20218
                     /locus_tag="IT892_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB family protein"
                     /protein_id="HAP3136415.1"
                     /translation="MTSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIV
                     PPVVDTLLLLSGIALMAKAHILPFSGQAQWLTEKLFGVIIYIVLGFIALDYRRMHSQQ
                     ARIIAFPLALVVLYIIIKLATTKVPLLG"
     gene            20222..21031
                     /locus_tag="IT892_003230"
     CDS             20222..21031
                     /locus_tag="IT892_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing protein"
                     /protein_id="HAP3136416.1"
                     /translation="MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSL
                     AKEEISQLLPLEEQLEKLIALFYGDWGFKASRGVYRLSDALWLDQVLKNRQGSAVSLG
                     AVLLWVANRLDLPLLPVIFPTQLILRIECPDGEIWLINPFNGESLSEHMLDVWLKGNI
                     SPSAELFYEDLDEADNIEVIRKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEI
                     RDRGLIYAQLDCEHVALNDLSYFVEQCPEDPISEMIRAQINNIAHKHIVLH"
     gene            21067..21921
                     /gene="kdsA"
                     /locus_tag="IT892_003231"
     CDS             21067..21921
                     /gene="kdsA"
                     /locus_tag="IT892_003231"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HAP3136417.1"
                     /translation="MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTV
                     TQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQA
                     QPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGN
                     EKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRR
                     AQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKG
                     FEELDTSK"
BASE COUNT         5448 a         5483 c         5598 g         5464 t
ORIGIN      
        1 aaatggcgca gatcaaatcc gctctggttt tgctgcatcc gataatcagc aaggatcatc
       61 agcggatcgc tgttcggcac ggcatcggca aaggtttttt ggtccggaaa aagtttggcg
      121 ttttgcacat cattaaacag cggccctaat aaaatatcag gcggctgtgg tgttaccggt
      181 gtttcttctg cctgcaccga tagcgcagcg aaacacaaaa agatacaggc tggaattaac
      241 gccatttttt gcgggcgaga aggtgcgggg gatttcatca atcattctcc tttggcgaaa
      301 ccgaataaaa cggtattcaa gtatcagaaa accttagttc aggatcgcac tagctgcatg
      361 atcgaaatct cattctgcga actgtcaggc attttagaaa agggaattaa agggataaat
      421 aacggcgaaa tagagtgatc aaataacgtc tgtttattag ccagccagcg gcgttgggtt
      481 cgtgattagc gaagaaaaat catcataaat tggtgaaaaa tataacaggt agttaaaaac
      541 cattagtgct gagtaaattg ccggatgaca tcagaacgat gccatccgaa cagtggctta
      601 accctgacgg ttgaaacgtt gcgttttaac gtccagcgtt agcgtttctt ctggttgtat
      661 cgcatacagt ttctcaccct gctggcaaat ccagccaatc cccagttcac gggcgattag
      721 ggcgctgtgg gataccggac ttccggcgct aaggcagata ccttttacaa ccgccggatc
      781 cagttgcagt actgtggaag gataaatgtt ctccgccagt agaatagttg gcgagttaaa
      841 ctgcgggagt tcttctttcg tttgggtcag gtggaccagg gtgcgatgca gaagatcgtc
      901 cacatcaata tagcgagctt gtagatattc atcatccagt tgctggtatt gctggctaag
      961 ttctttaaga acttgctgcc aggcatattc tgccgtgcaa tgttcatgct gaaggagttc
     1021 gcttgccgcc gccagcagtt ccggatcatc taacagtgta tggtgaccag aaaagattgc
     1081 ggcaatatcg tcaagcccgc tggcttctgc tttcgctgtt aacgtcatca gatctaataa
     1141 cgtgaagtca atagcctggc gtaatcgatc ttgttcttct tccacggtca gggttgattt
     1201 tgcctgtacc gtacataaaa ctggttgata ataaaaggct ttacccgaaa caggcggaac
     1261 gggacgcaga gtaggtggag cgacttcctc cgtttcacca aagttatctt cagccagctg
     1321 acggaaagcg atcagtgcct cttcagcttc tggccctttc gcaatcaggc gcagcgtatc
     1381 gttatagcga acttgtagta acgcaatctg gttaatactc tctggtgtga cgcatttgcc
     1441 gtttttttcc agcaacatat cggcattaaa tgtcgataag gtataaacca gccgggaggc
     1501 cggacgtaca tgcaggccgt tacggttttt tatgaccacc gccagagaac gggcttcttc
     1561 atcgtacgca ggacatgtgt cagagatttc agtgtcggag gacggtaaac ccagttgttc
     1621 acgtttggct tccagcgcat gcatggcgtc aaagataact ttgtcgatat ccgcccccga
     1681 ggccgcgctg accgttgctg ccagtgtacc ttcgaccaac ggcgcagcac acaaacgtac
     1741 ttttgcggcg atctcgggag ccagcaattc cagcgcagtt tcagcactca ataatgcgct
     1801 acccatatcc atcatgacca gcacatggtc ggcatcagca acagattcga tggcctccat
     1861 cactttgacg gcatcggtac caatgggatt ttgtggatcg tcaattcccg cggcaatggc
     1921 gattttacaa ctatcactca ttaacatctg acgggctaat tcaccgacac cttctcccag
     1981 tcggctgcta tgtgaaacta tgaccaggtt taccatcacc aattccttac tcttttgcgg
     2041 ctaacgccaa catttgcatc ataaacatca ccgaggtcgc gccgggatcc tggtgaccaa
     2101 tactgcgttc accgagataa ctggcgcggc ctttgcgggc ttgcatcgta atcgtacttt
     2161 gtgcagcgga ttcggcgatg ctactggcag cttcgagcgc caccggaaca gagagatttt
     2221 gctcgctgga ctgacgtaac gattccacca ccggcaccca cacatcacac atggttttat
     2281 cgccaggttc ggctttcccg cgactgatta cgccgtccgc gccatcgcgg aacatctgat
     2341 aaagctcttc cagtgtcagg ctttgccgtg cctgggtcgc ctgtgcggcg cggataaaga
     2401 aggtaccgaa cagcggacca ctggcaccac cgacgctgga aagcagcgtc ataccggtat
     2461 tcttgagaat gaaaccgata tctttatctg cgatagcagg gagtttttcc accactttgc
     2521 taaagcctcg gttcatattt agcccgtggt cagcatcgcc aatttcgcga tccagtccgg
     2581 taagatactc gctctcggtg ctgaaaatat cgccacaacg agtgagccag ttaacaattt
     2641 gagttctgct cagtgacatt gctttctcct tatttacccc agttaagggc cggggtgtgg
     2701 accggggcgt cccagagtgc cagcgtttcg tcatcaactt tcagtaaggt gattgagaaa
     2761 ccggtcatat ccagtgaggt gcagtacgcg ccaattaaat tacgttcgat agtcaatccc
     2821 gcttgctggc aacgtgtggt caggcggtta tagacgccgt acagctcaga aagcggagtt
     2881 gcgccaagat tgttaaccag cgcaatcacc cgatcgccag actggagcgg ttgtttggtt
     2941 tgttgttctt cctgccaact gccttgttga taatcccaga aacgcaaagt gcgatggtat
     3001 gagccattta ccagcagggt gtcgaacatt tcatcgacgg tttgatcaag ggaagagaag
     3061 gggcggcggt caatacccgg ctcaccatga atgccgacgc caaactccat ctcattatcc
     3121 gccagggtaa aagaaggttt gcccgcggca ggaacggtac aggcaccgag agcgatacct
     3181 attgagtggc cttgattatt cagcttacgc cccagttccg cacaggcgtc cagtgagtcg
     3241 ccacgctccg ccgctgcgcc tacgagtttt tcaattaata cggtgttggc aacgccgcgt
     3301 cgcccggcag tataaagact gtcttttacc gcaacgtcgt catcaatgac cacagtggtc
     3361 acttttacgc cgctatcgtg cagtaactcg gtcgctgttt caaagttaag aatatcgccg
     3421 gtgtaatttt tgataatcaa cagtacacct tcgccgccat caacttgcat ggcgcattca
     3481 aagattttat cgggcgtcgg tgaggtgaaa atttcgcccg gacaggcccc cgaaagcatc
     3541 ccctgaccga tataaccaca gtgcatcggc tcgtgtccgc tgccgccacc cgacagcagg
     3601 gcgacttttc ctgcaacagg ggcatcagct cgggtgacat acaccggatc ctgatgcagt
     3661 gtcagcgatg gatgcgcttt cgccagtcct gccagttgtt cgtccagtac gtcttgcaca
     3721 tcattgatca attttttcat tattttgctc cagcaattac ggtagggcat ggatgatgtt
     3781 caacgacacg gcgaccactg actgccgatg aatccattgt gcatcaggca agggaaaaga
     3841 aaattagccc aaattatgtt tcatagtgaa acatatgctt taatgaatgt tccatattga
     3901 aacttttacg tgtattaata cttaaaattg cgagccggaa caccttttgt cataagggat
     3961 gcgggatatg agtggcgctt ttaacaacga tggtcggggc atatctccct taattgcaac
     4021 ctcctgggag cgatgcaata agctgatgaa acgggagaca tggaacgtac cacatcaggc
     4081 ccagggcgtg acatttgctt ctatttatcg gcgtaagaaa gcgatgctga cgctcgggca
     4141 ggctgcgctg gaagatgcct gggaatatat ggcaccgcga gagtgtgcgc tgtttatcct
     4201 cgatgaaacc gcctgcattc tcagccgtaa tggcgatccg caaaccttgc agcagctaag
     4261 tgcactggga ttcaatgacg gcacgtattg cgccgaggga attattggta cttgtgcgct
     4321 atcgttagcg gctatctctg gtcaggccgt gaaaacgatg gccgatcaac atttcaaaca
     4381 ggtactctgg aactgggcct tttgtgcaac gccgttgttt gacagcaagg gccgattgac
     4441 gggaacaata gcgctggcgt gtccggttga gcaaactacc gcagctgatt tgccgttgac
     4501 gttggcaatc gcccgcgagg tcggaaattt actgctgacg gacagtttgc tcgctgaaac
     4561 taaccgtcat ttaaatcaac ttaatgccct gttagaaagt atggatgatg gcgtgattag
     4621 ctgggacgag cagggtaatt tgcaatttat taatgcccag gcggcgcggg tcttgcgcct
     4681 tgacgcgacg gcaagtcagg gacgggcaat cactgaactc ttaacgttac ccgccgtatt
     4741 gcaacaagca ataaaacagg cacatccgct caaacacgta gaagcaacct ttgaaagcca
     4801 gcaccagttt attgatgcgg tgataaccct taaaccgata atagaaacgc agggaaccag
     4861 ctttattttg ttgctccatc ctgtggaaca gatgcggcag ttgatgacca gtcaattagg
     4921 aaaagtcagc cataccttcg ctcatatgcc acaggacgat ccgcaaaccc gccgcttgat
     4981 tcattttggt cgccaggcgg cgcgcagtag ctttcctgtc ctgctttgtg gagaagaggg
     5041 cgtgggcaag gcactgctaa gtcaggcaat tcataatgaa agcgagcgtg ctgcaggtcc
     5101 ttatatcgcc gtcaattgtg agttatatgg tgatgctgcg ctggcggaag aatttattgg
     5161 tggcgatcgc acggacaatg aaaatggccg tctgagtcgg ctggaactgg cacacggcgg
     5221 cacgctgttt cttgaaaaga ttgaatatct ggcggtggag ttacagtctg ctttgcttca
     5281 ggttatcaag cagggggtta tcacgcgact ggatgcgcgg cgtttaatac caattgatgt
     5341 caaagtgatt gcaacaacga ccgcggacct cgcaatgctg gtggaacaaa atcgttttag
     5401 tcgccagctg tattacgcgc tgcatgcatt tgaaattacc atcccgcctc tgcgtatgcg
     5461 gcgtggcagc attccggcgc tggtgaataa caaattacgc agtcttgaaa aacgcttctc
     5521 tacgcggctg aaaattgatg acgatgccct cgctcgcctg gtttcttgtg catggccagg
     5581 caacgatttt gaactttaca gcgtcatcga gaatcttgct ctgagtagtg ataacgggcg
     5641 cattcgcgtc agtgatttgc cggaacatct gtttaccgag caggcgacag atgatgtcag
     5701 cgccacccgc ctttccacca gtctgtcatt tgcggaagtt gaaaaagagg caattattaa
     5761 cgcagcccag gtcacaggcg gtcgcattca ggaaatgtcg gctttacttg ggatcggccg
     5821 cactacgctg tggcggaaaa tgaagcaaca tggcattgat gcagggcagt ttaagcgccg
     5881 ggtatgaaag acagaaacga tttctgatac atcagagtga tctgtatttc attccggcgc
     5941 acgctaacaa ttttcagcat cgtttaaggg cttgtctatc ccgcacttaa aagctgaagc
     6001 gatatcctcc gttgacttgc ttctgatcaa agaggttacc ctgcgtgtaa tccgcttcga
     6061 gatagaatgt gtgctgtttg ttatactgtg cactgactcc cacgccgtta ttccagccat
     6121 tacctttgaa actgtacttc tcccgggagt tgttcaacag atattcggta tcccctgaaa
     6181 actcgcggat agcgccagtc ttcacataga cattcagctg gctgttgcct gcggtgatgt
     6241 cataccccag tatcatgctg gcacgcccca gcagcgattc gtagtgattc agatgtatat
     6301 tgaggccatt actcgccttc atagtcatct cattctggtg gctgtatgta agctgggttt
     6361 gcggctctat atagaaccca taaccagtag gggacaggtt gaacctctgc ccggcttcca
     6421 gggagatgct cattccattc gcagtgccgt tggcgttaac gccgttgttc tgactgtcca
     6481 gtacgtggaa actatttttc tggcgcgatg cttttataac gagatcgctg taaaaaccgt
     6541 tttgtgccat gtaactggcg tacattccca tgtagtctga acgtgcggta ccgtcgcctc
     6601 cgctatagtc cggcgatgca tgtgttgagc caatatacag accgacatac aacggcatta
     6661 catcagagag acgtttatcc ccaccaaact ggataccgct gtaacccatg tcaaagccgc
     6721 tcagtttgcc actggcaaag gagtccaggc ttcccccata actgcgcaac cagatattac
     6781 cgtctttact ctgatttcgc aggtcaccca tccgttgcat cagcgtacgg ttttcaacat
     6841 agttcaataa gtaaccgaca ttgagataat tgccgccagc atctgcggtc gtggtgggtt
     6901 taggcgtggg agcgggttca ggcgtaggat cggggttgac tatgggaggc tgagcgggag
     6961 ctggtgtggg ttcaggatta ggagtcggtt ccggaactgt cccggaagcg taaagctccc
     7021 agttagtgcc atttttacgc acatcgtaca gatatccccc caactcaacc tgagaagacg
     7081 cgctgaacga ggccgcgccg tcagtggttt ttaccactgt cagaacttca tttcccgttg
     7141 tggcctcgct gccctggttg cggatagcca atacgtgatt accagcacta ctcccgctga
     7201 tattcaataa atccccttta ttattaacgc cattaccctc gccaacaaca tcagcacgca
     7261 taataaaggt actgttaccg ctcaggttct ctacgtttaa tgtggcaaat gtgccggcag
     7321 ttgacccgtg gctggcaaaa tcgacagttg aatggctcag cgccagcgtg tcgagattag
     7381 aattacttgt tacgttccag acgctgttat tcattgcaac gtccagtttt ccgccattga
     7441 cattatcgct gagggaggaa cctgtccaaa ccgacccagg gtgcatatcc agattgatta
     7501 gcccaccttt ggaaagaacg ctaccgttga taagcatacg acccgaggcg ttgatgcggc
     7561 tggcggcata accatcgtca tgttgcgttg cgatggccat ctggtcgggt gtactcatat
     7621 caatgaccag atcgctcgtg aggtcgatct ggctgttggt catggcataa attcccctgg
     7681 ctcctgccgc gccggtgata gccaaactgt ctccggttat tctaccgccg ctgagagccc
     7741 acaaacccag cgccagactg ccattacgat caactgtaat atcggtattt tgcatgttga
     7801 caacagccgt tgccgtctgg gccgaggcac cataagaacc gccggaaaag atgctgtttc
     7861 gttgcgctgc cgtgccagta aaattgatta tcgcgtctga accactggtg acgaggccac
     7921 cgccctgcgc ggaagaaata tggctatctg caccgatagt ggttgtacca ccacgaactt
     7981 cgacgccatt ggccgcggct ccagttacat caacagtgag tgcattcgcg ctaacctggc
     8041 caaagctcca gaggccgtga gcattatcgc cattggtttt aatggtactg tttgttccga
     8101 gatcgacaac agagtttttc tgtacgttta tccccatggc gctgtagccc tgaacatcga
     8161 ttgtcaggtc tgtagccgta aaacgcgcag caccattggc gttattgccg ttgagaccac
     8221 cgatataaac acctgtactt ccatcggtcg tgattttact tccgcttcca agatcgacac
     8281 tggtgccata gtcattgatg gttaggccta taccgttcga gttttcaatg gtgaattgag
     8341 tggctgttag tgttgagcta tgcccaataa tgatgccgtc atcgttactc ttaatggtgc
     8401 tgcctgtgcc taagtcagca tgggtatagt caccaattaa gttaatgccg atggcagagg
     8461 tttgaccaac aacatctact gtgagtcggt tagctgtcag ggagctgttt ttgccctgaa
     8521 taatgattcc ttttgcatat ccagaggcgt cgttgacatt gacggtgaca tcattaccca
     8581 ggttgatatt gccaggcgtg tttcctgctg gggtcattac accatagagg tttcctgatg
     8641 gatcggcggt atctcctgta attctgtcac catcattaat agtaatattg gtgccatatt
     8701 gacttcctgt atcagcagct atcagcaggg gggaaaagat aattgcattc aaaccaatag
     8761 cgccaaattt tatcagttga attgagggcg aacggatttt taattcagcg agacgatctg
     8821 ctttggtatt cccattgtgt tgtttgatgc ccataccact cctatatagt acccagacta
     8881 tgggtctatg gattttgtca ttttgtttaa atcaatgaat aatatcctct tatcatcatg
     8941 atatttgtat ggtgcaatca tgatgagctt ctcagagaat aattctctat taccgggcaa
     9001 aatcaggaac acaggaatta atatatattt aacatccccc ttacaaaggt gagtttatat
     9061 cgagttattc cctaagttgt cgttacttat tccaattcgt tactataaat atggcaaaaa
     9121 tattacaaca aacagcggtt aaaaaatttg gtgaagattt tttgtaataa tcctaattag
     9181 ttatgggaat ttcgcttgat gtatctgcat aacaaaaaca atatgcgcca tttttgcatt
     9241 actaataaga aaaagcaaaa aacatcgata ttcatttttg gtcaatgggt tttctggcct
     9301 atcgttgtta ttgtgctact ggttatcatt ttcatcttgc cagcatattg gagcgtgatc
     9361 aattttgatc agctgtgaag ggggctgatg tgtagtgata caaaaactta cgttatatca
     9421 ctgctaatga gatatccgtc atctgaacac ttatgtcttt aattattctc gtggttcact
     9481 ataggcaata agcacaaaag tgtaggatgt tacaagaatg attaggactc ggtgaaatga
     9541 aaaatccacg caattgcgtg gattttatat acttttgcgc tcttcatgag atttagcgaa
     9601 acctcatgag acaataaatt aattagacgt tgaaaaggaa gttcatcaca tcgccatctt
     9661 tcacgatgta atctttacct tctgcacgca ttttgcctgc ttctttcgcg ccttgttcac
     9721 ctttgtaagt gatgaaatct tcaaacgaga tggtttgtgc acggataaag cctttttcaa
     9781 aatcagtatg gattttgccc gctgcctgcg gcgcggttgc tccaaccgga atggtccatg
     9841 cacgcacttc tttcacccca gcggtgaagt aagtttgcag gttcagcagt ttataaccgg
     9901 cacggatcac acggttcagg cccggctctt ccagcccaag ctcctgcata aactcgtcac
     9961 gttcttcgtc gtccagttcg gcaatgtctg cttcaacagc agcacaaacc ggaaccacaa
    10021 cagaaccttc tttcgccgcg atttcacgca cctggtcaag atatgggttg ttttcaaaac
    10081 cgtcttcgtt gacgttggcg atgtacattg ttggtttcag cgtcaggaag ctcaggtaac
    10141 gaatagccgc tttctcttca gcgcttaaat ccagcgcgcg cagcatacct gcattttcca
    10201 actggggcag gcatttttcc aggaccgcca gctcagcttt cgcgtcttta tcgccgcctt
    10261 tggctttctt ctgtacgcga tgaatcgcac gttcgcaggt gtcgaggtct gccagcgcca
    10321 gttcggtgtt gataacttca atatcgtcag ccgggttaac tttgccggaa acgtgaatga
    10381 tgttgtcatt ttcaaagcag cgaacaacgt gaccgatcgc ttcggtttca cggatgttgg
    10441 tcaggaactg gttacccaga ccttcgcctt tcgatgcgcc ttttaccaga ccggcgatat
    10501 cgacaaattc catggtcgtg ggaagcgtac gctgcggttt tacgatttca gccagttgat
    10561 ccaggcgagg atcaggcatt ggtacgacgc ctgtgttcgg ctcaatggtg cagaatggaa
    10621 agttggccgc ttcaataccg gctttggtca gcgcgttgaa cagggtagat ttcccgacgt
    10681 tgggcaaacc gacgataccg catttgaatc ccatgattta aatcacctta atatcttaat
    10741 aatcaacctg ttattgctaa cagattgcag aaatggaaat aactttgcct attatacacg
    10801 gcactcggca aaaatgccgc agacaacgac ttattgcgct ttaaaggcgt gcaatcggtt
    10861 cgttgctttg gtcaagccat ctgtaaacca catttcagta caacgcgccg cttcgtcaat
    10921 ggcttcatca attaacttct gttcactaac aggcggtttg cctaacacaa aaccgacaac
    10981 tttattttta tcgcccggat gaccgattcc gatgcgtaaa cggtgaaagt tagggttatt
    11041 acccaattta ctgatgatgt ctttcagtcc attgtgacca ccatggccac cgcccaattt
    11101 aaatttggcg acgccaggag gcagatccag ttcgtcgtgg gccaccagaa tttcgtccgg
    11161 attaatgcgg aaaaaactgg ccatcgcggc aacggctttg ccgctgagat tcataaatgt
    11221 agtcgggact aacaggcgga catcttcgcc tccaagagtg actcgcgaag tataaccaaa
    11281 gaatttagcc tcttcgcgca gcggagcgcg caaacgctct gccagtaagt caacgaacca
    11341 ggcaccagca ttatgtcgcg ttgcggcgta ttcagcaccg gggttcgcca ggccgacaat
    11401 caatttaatc gtcacgtttt tttgtcctga gtgtgtacat aactggcgcg tagtttactg
    11461 gttgcggccc cgcttgacaa aaaactgcgt atcaaatgca gataacgtaa taattgcctg
    11521 agtggactat tagaaagtca aggtgttcag gcgtttattt gtaaagtttt gttgaaataa
    11581 gggttgtaat tgtgatcacg cccgcacata acccactggg tgttgtctat actttacaca
    11641 taaggaagag gggtattccc tgttacaacc cagaaagttc cggaggtgac atatgaaacg
    11701 caaaaacgct tcgttactcg gtaacgtgct catggggttg ggtctggtgg taatggtggt
    11761 cggcgtgggg tattcaatcc tcaaccagtt accacagttt aatatgcccc agtatttcgc
    11821 acatggtgca gtgctaagta ttttcgtcgg tgccattctc tggctggcgg gtgcccgtgt
    11881 tggcgggcat gaacaggtgt gcgaccgtta ctggtgggtt cgccactatg acaaacgttg
    11941 ccgccgtagc gataatcgcc gtcatagcta acaaataatg cagtttgctg accagtcagt
    12001 ttgcgctgac tggtcaatct cgtacttata aatccgccat cgccgcgcga cgattcggga
    12061 agaacgccag gcgtcccggg atcggttgaa tgccagcgcg agccatagtg cgcagtggct
    12121 ggaattccac gttgcacacg cgcagttcac atccctcggg cagacgcttc acaaaacgct
    12181 ggaacgcatc aagaccacca gcatcaagta ccggaacggc atcccacttc agaatcacaa
    12241 tccgttttcc ttcaagacgt gactccaggt ccgtgaataa gccttcagca gcagcaaaaa
    12301 acagcgggcc aataacgcgc agaaccagga catcgtctgg aacatctacg actaccggtg
    12361 ccaggcgagt catacgtgcg atacgacgca taaacagcag cgatgccagc acgatcccca
    12421 cgctgatggc aataaccata tcaaacaaca cggtcagcga catgcacagc agcatgacga
    12481 tgatgtcatc tttcggcgca tgacgcagca agtcgaccac tttgtgcgct tcactcatgt
    12541 tccacgccac catcaacagc agggctgcca tggcggaaag cggcagccag gagagcagcg
    12601 gtgccagtac cagcagggca agaataacca gaatagagtg gatcaccgcc gagatagggg
    12661 acgttgcccc ggcacggacg ttagcggcag aacgcgcgat ggcagctgta gcggtaatac
    12721 caccaaagaa cggagcgata atattcccca gtccctgtcc aaccagttcg ctgttcgcct
    12781 tgtgtttcgt cccggtcata ccatccagca ccacggcgca gagcagagat tcgattgcgc
    12841 cgagcattgc cattgagaat gccgcaggca gcagtgtgcg aatagaatcc caggttagcg
    12901 tgaattctga attaggcaga tcccacggca gcaccagttg cggcagcagt tgcggaatac
    12961 cgttaccctg agaaccatcg gccaggacgt agtggaattg cgaaccgatg gtagcaacat
    13021 gtccgccgag caggttaaca atccccatca ccgcgcaacc agccagcaag gccggaaggt
    13081 gaccgggtaa acgaatgccc agacgcggcc aaaaaacaag aatacctagc gtcacaatgc
    13141 caatggcagc atcacccaca ttaatggtcg gcagcgccat aaataatgcg ccgacttttt
    13201 gtagataatg ttccgggaca tgggccattt gcagaccgag aaaatcttta atctgcatgg
    13261 taccgatggt gatcccgata cccgaggtga aacctaaggt gacggaaacc ggaatatact
    13321 caatcaggcg accaaagcgt gccagaccca tcagaatcaa aaagatcccc gacagcaagg
    13381 tcgcaaccag cagtcctgcc agtccaaact gttgcgacac gggatagaga attaccacaa
    13441 atgccgcagt cggaccggaa acgctaaagc gtgacccacc cgtcagagca atgacaatcc
    13501 ccgcaacagc tgcggtatat aaaccgtact ggggtgccac accactacca atagccaacg
    13561 ccatcgccag cgggatagca ataatcccga cggttatccc ggcaatcagg tcacgggtaa
    13621 accgtgcggc agtatatttt tctttccagc aagcgtcgat cagagcgcgg aaaggcatca
    13681 catgtgagga aaatattttg ttcacaataa tgtttcatcc gtgagcgcat catctgtcaa
    13741 ctaaatggca ggtgaaggag gcataggtca tacaaatgga tattacagac aaaaaaaccc
    13801 gccgcagcgg gtctttgagc cgggttcgat tagtgttcga acatggcaga gatcgattct
    13861 tcgttgctga tacgacgaat cgcttcggcc agcatacctg acagggtcag agtacgcacg
    13921 ttcggcagtg atttgatttc atcgctcagc ggaatggtat cgcagacaac gacttcatca
    13981 attacagagt tacgcaggtt gttcgccgcg ttgccagaga agatcgggtg agtcgcgtac
    14041 gcaaatacac gtttagcacc acgttctttc agagcttcag cagctttaca cagcgtaccg
    14101 ccagtgtcga tcatatcatc gaccagtacg cagtcacgac ctgcaacgtc accgatgata
    14161 tgcatcacct gtgaaacgtt cgcacgcgga cgacgtttgt cgatgattgc catatcggta
    14221 tcgttcagca gcttagcgat agcgcgggca cgcacaacgc cgccgatgtc cggagaaacc
    14281 acaattgggt tatccagatt cagctgcagc atgtcttcca gcaggatcgg gctaccaaat
    14341 acgttatcaa ccggaacgtc gaagaaaccc tgaatctgtt cagcgtgcag atccactgtc
    14401 agcacacggt caacaccgac gctggagagg aagtctgcaa ccactttcgc agtgattggt
    14461 acacgagcgg aacggacgcg acggtcctgg cgcgcatagc caaagtaggg gataacagcg
    14521 gtgatacgac ctgcggaagc acgacgcagg gcatcaacca taacgactaa ttccatcagg
    14581 ttgtcgttag taggggcaca agtggactgg atgatgaaaa tatcaccacc gcgtacattt
    14641 tcattaattt gtacgctgac ttcgccatcg ctaaagcgac ctacagcggc gtcgccgagt
    14701 gaagtgtaca ggcggttggc aatacgttgt gctagttccg gggtggcgtt accagcaaaa
    14761 agcttcatat caggcacgag aagaacctca ggcatgcgtc cattggtgga aagaatctgc
    14821 cgaaaactgt gcgggccagg catgatcctt tccaggcggt gtattaaaga gcgcgatgca
    14881 acgtctggaa caaggtgacg ttgtcaccga aactcagctt gcccggctta aagcatggct
    14941 ctgtgcaatg gggaaagatt agcgcctttc gccacaaagc cattgagcca ttccggggct
    15001 tgctctagca cctggcgggc ttcagactct gtatcaaatt cagcaaagac acaggcccct
    15061 gtcccagtca ggcgcgacgg ggcgtattct aacagccagg aaagcaccgc atcaacctcg
    15121 cgaaaacgtt ttcttgcgat aacctcgcaa tcattgctga attcacattt tagcaacgtt
    15181 tctattgacc tttttggcgt attgcgcggg agttcaggat ctttaaaaat caccggagtc
    15241 ggaatactta caccagggtg cgccaccaga taccacttct ctggcggatc caccggcgtt
    15301 agtatttcac caacgccttc ggcaaacgcg gcatgccccc gaacaaagac aggaacatct
    15361 gcgcccagcg tcagccccat ttccgccagc tcatccatgc ttagcccgca ttgccagaga
    15421 tgatttaatg ccaccaggac cgtcgcggca ttggatgaac caccgccgag accgccgccc
    15481 atcggcaaac gcttgtcaat gctgatattc gcaccgcttc ccgtcggaag acgcccgctg
    15541 tctgccgcag ttttcatcaa caatcgcgct gcgcgaacga tcaggttatc ttcatgttcc
    15601 acgccttcaa cgggcgttaa cagacgaata tccccatcgt cacgaagctc aatgctgatg
    15661 gtgtcgccgt aatcaagaaa ctgaaacagc gtttgcagcg tgtggtaacc atccgcacgc
    15721 tgaccggtaa tgtataaaaa cagattaagt tttgccggag agggccactg tgtccgcatt
    15781 atttcactat ccagttatcc atttttaact tgatgcgttg accaccgtcg gtgagttcca
    15841 tattggctgg catcgcaggt tgcgttttgg tgtcataacc accataaaca accttccagt
    15901 ttttgccatt ctggctgtag gtaatttcgc tcaggcggta ctggtcgtcc agtttgtagt
    15961 cggttgcatc acccggtaaa cctaaaatcc actggcgcaa gctgttgagc ggaattggca
    16021 ttccggtcaa tttgccaatc atctcttcgg cgtcatcggc ggtataacgc tgacctttat
    16081 tgtcgactaa ctgcacgtta cccggttgag cattcagctc cagttccgtg ctgcccaatg
    16141 ggttagtgag cagcagacgg tagcgatcct ggccggtttg ctgccagaaa aagcgggcgt
    16201 acactttttg ttggtcagaa atataagcga acgcgccgcg agtctgatac tgattaagat
    16261 tgcgcacgtc ttgctgatgc tgacgccatt gtggcgaatc cgggcttttg ccaggacctt
    16321 tgggcgtggt aacggaacag gcagtgagca caagagcagc cagcggtagc aggcggataa
    16381 gacgaaaatc gggcaggggc atagtgatga caagtccttg agatacgttg cagttataac
    16441 ccttaatgct agcgttaccg tccgctatcg tctatgttca agttgtctta attgccagaa
    16501 tctaacggct ttcggcaatt actccaaaag ggggcgctct cttttattga tcttacgcat
    16561 cctgtatgat gcaagcagac taaccctatc aacgttggta ttatttcccg cagacatgac
    16621 ccttttagca ctcggtatca accataaaac ggcacctgta tcgctgcgag aacgtgtatc
    16681 gttttcgccg gataagctcg atcaggctct tgacagcctg cttgcgcagc cgatggtgca
    16741 gggcggcgtg gtgctgtcga cgtgcaaccg cacggaactt tatcttagcg ttgaagagca
    16801 ggacaacctg caagaggcgt taatccgctg gctttgcgat tatcacaatc ttaatgaaga
    16861 agatctgcgt aaaagcctct actggcatca ggataacgac gcggttagcc atttaatgcg
    16921 tgttgccagc ggcctggatt cactggttct gggggagccg cagatcctcg gtcaggttaa
    16981 aaaagcgttt gccgattcgc aaaaaggtca tatgaaggcc agcgaactgg aacgcatgtt
    17041 ccagaaatct ttctctgtcg cgaaacgcgt tcgcactgaa acagatatcg gtgccagcgc
    17101 tgtgtctgtc gcttttgcgg cttgtacgct ggcgcggcag atctttgaat cgctctctac
    17161 ggtcacagtg ttgctggtag gcgcgggcga aactatcgag ctggtggcgc gtcatctgcg
    17221 cgaacacaaa gtacagaaga tgattatcgc caaccgcact cgcgaacgtg cccaaattct
    17281 ggcagatgaa gtcggcgcgg aagtgattgc cctgagtgat atcgacgaac gtctgcgcga
    17341 agccgatatc atcatcagtt ccaccgccag cccgttaccg attatcggga aaggcatggt
    17401 ggagcgcgca ttaaaaagcc gtcgcaacca accaatgctg ttggtggata ttgccgttcc
    17461 gcgcgatgtt gagccggaag ttggcaaact ggcgaatgct tatctttata gcgttgatga
    17521 tctgcaaagc atcatttcgc acaacctggc gcagcgtaaa gccgcagcgg ttgaggcgga
    17581 aactattgtc gctcaggaaa ccagcgaatt tatggcgtgg ctgcgagcac aaagcgccag
    17641 cgaaaccatt cgcgagtatc gcagccaggc agagcaagtt cgcgatgagt taaccgccaa
    17701 agcgttagcg gcccttgagc agggcggcga cgcgcaagcc attatgcagg atctggcatg
    17761 gaaactgact aaccgcttga tccatgcgcc aacgaaatca cttcaacagg ccgcccgtga
    17821 cggggataac gaacgcctga atattctgcg cgacagcctc gggctggagt agcagtacat
    17881 cattttcttt ttttacaggg tgcatttacg cctatgaagc cttctatcgt tgccaaactg
    17941 gaagccctgc atgaacgcca tgaagaagtt caggcgttgc tgggtgacgc gcaaactatc
    18001 gccgaccagg aacgttttcg cgcattatca cgcgaatatg cgcagttaag tgatgtttcg
    18061 cgctgtttta ccgactggca acaggttcag gaagatatcg aaaccgcaca gatgatgctc
    18121 gatgatcctg aaatgcgtga gatggcgcag gatgaactgc gcgaagctaa agaaaaaagc
    18181 gagcaactgg aacagcaatt acaggttctg ttactgccaa aagatcctga tgacgaacgt
    18241 aacgccttcc tcgaagtccg agccggaacc ggcggcgacg aagcggcgct gttcgcgggc
    18301 gatctgttcc gtatgtacag ccgttatgcc gaagcccgcc gctggcgggt agaaatcatg
    18361 agcgccagcg agggtgaaca tggtggttat aaagagatca tcgccaaaat tagcggtgat
    18421 ggtgtgtatg gtcgtctgaa atttgaatcc ggcggtcatc gcgtgcaacg tgttcctgct
    18481 acggaatcgc agggtcgtat tcatacttct gcttgtaccg ttgcggtaat gccagaactg
    18541 cctgacgcag aactgccgga catcaaccca gcagatttac gcattgatac tttccgctcg
    18601 tcaggggcgg gtggtcagca cgttaacacc accgattcgg caattcgtat tactcacttg
    18661 ccgaccggga ttgttgttga atgtcaggac gaacgttcac aacataaaaa caaagctaaa
    18721 gcactttctg ttctcggtgc tcgcatccac gctgctgaaa tggcaaaacg ccaacaggcc
    18781 gaagcgtcta cccgtcgtaa cctgctgggg agtggcgatc gcagcgaccg taaccgtact
    18841 tacaacttcc cgcaggggcg cgttaccgat caccgcatca acctgacgct ctaccgcctg
    18901 gatgaagtga tggaaggtaa gctggatatg ctgattgaac cgattatcca ggaacatcag
    18961 gccgaccaac tggcggcgtt gtccgagcag gaataatgga atatcaacac tggttacgtg
    19021 aagcaataag ccaacttcag gcgagcgaaa gcccgcggcg tgatgctgaa atcctgctgg
    19081 agcatgttac cggcagaggg cgtactttta ttctcgcctt tggtgaaacg cagctgactg
    19141 acgaacaatg tcagcaactt gatgcgctac tgacacgtcg tcgcgatggt gaacccattg
    19201 ctcatttaac cggggtgcga gaattctggt cgttgccgtt atttgtttcg ccagcgacct
    19261 taattccgcg cccggatacg gagtgtctgg tggagcaggc actggcgcgg ttgcctgaac
    19321 aaccttgccg tattctcgat ctcgggacgg gtaccggggc gattgcgctt gcgctggcta
    19381 gcgagcgccc ggactgcgaa attatcgctg tagatcgtat gcctgatgct gtctccctgg
    19441 cacaacgtaa tgcccagcat ctggcgatca aaaatatcca cattctgcaa agcgactggt
    19501 ttagcgcgct agccgggcag cagtttgcga tgattgtcag caatccgccg tatattgacg
    19561 agcaggaccc tcatcttcaa caaggcgatg tccgctttga gccgctcact gcgctggttg
    19621 cggcagacag tggaatggca gacatcgtgc atatcatcga acagtcgcgt aacgcgctgg
    19681 tatccggcgg ctttctgctt ctggaacatg gctggcagca gggcgaagcg gtgcgacaag
    19741 catttatcct cgcggggtat catgacgtcg aaacctgccg tgactatggt gataacgagc
    19801 gcgtaacgct cggccgctat tatcaatgac aagtttttct acactgctta gtgttcatct
    19861 tattagtatc gcgctttctg ttgggctatt aaccttacgt ttctggctac gttatcagaa
    19921 gcatccacag gcatttgctc gctggacgcg cattgtgccg ccggttgtcg atacgctgtt
    19981 actgttaagc ggcattgcgt tgatggctaa agcgcacatc ctgccatttt ccgggcaggc
    20041 acagtggctg actgaaaagc tgtttggagt tatcatttat atcgttttgg gttttattgc
    20101 actcgattat cgtcgtatgc acagtcagca ggcgcgcatt attgccttcc cgctggcgtt
    20161 ggtggtgctg tacatcatca ttaaactcgc caccacaaaa gtaccgttac tggggtaagt
    20221 catgagatcg ttagctgatt tcgaatttaa taaagcgcca ttgtgcgaag gcatgatcct
    20281 ggcttgcgaa gcaatccgcc gcgattttcc ctcgcaagat gtttacgacg aactggagcg
    20341 tctcgttagt ctggcgaagg aagaaatcag ccagcttctg cctttagaag agcagttgga
    20401 aaaactgatc gcgctgtttt acggcgactg gggatttaaa gcctcacgcg gtgtttatcg
    20461 tctttccgat gcattatggc tggaccaggt gttaaagaat cgacagggca gtgcggtatc
    20521 attaggtgcg gttttattat gggtcgcgaa tcgtctcgat ttgccgctgc tgccggtgat
    20581 tttccctacg cagctgatat tgcgcattga atgtccggat ggcgaaattt ggctgattaa
    20641 tccttttaac ggtgaatcgt taagcgaaca tatgctggac gtatggttaa agggaaatat
    20701 cagcccgtcg gcggaactgt tttatgaaga ccttgatgaa gctgataaca ttgaggtaat
    20761 ccgcaaattg ctggatacac tcaaagcctc gttgatggaa gaaaatcaga tggagctggc
    20821 gttacgcacc agcgaagctt tattacaatt caaccctgaa gatccctatg aaattcgcga
    20881 tcgcgggttg atttatgcgc aactggattg cgaacacgtt gcgttgaacg atttaagtta
    20941 tttcgttgaa cagtgtccgg aagacccgat cagcgaaatg atccgtgcgc aaataaataa
    21001 catcgcgcat aaacatattg tgctgcatta attaatcgac attttactca agattaaggc
    21061 gatcctatga aacaaaaagt ggttagcatt ggcgacatca acgtagcaaa tgacctgccg
    21121 ttcgtactgt ttggcggtat gaacgtgttg gaatctcgcg atctggcgat gcgcatttgc
    21181 gagcactacg taactgtgac ccagaaactg ggtatccctt acgtgttcaa agcctctttt
    21241 gacaaagcca accgctcctc catccactct tatcgtggac cgggcctgga agaagggatg
    21301 aaaatcttcc aggagttgaa gcagactttt ggcgtgaaaa ttatcaccga cgttcacgaa
    21361 ccaagtcagg cacagcccgt tgctgatgtc gtggatgtga ttcagttgcc ggcgtttctt
    21421 gctcgccaga ctgacctggt tgaagccatg gcgaaaaccg gtgcggtaat taacgtcaag
    21481 aaaccacagt ttgtcagccc gggacagatg ggtaatatcg ttgataaatt caaagaaggc
    21541 ggcaacgaaa aagtgattct ttgcgatcgc ggtgctaact tcggctatga caacctggtt
    21601 gtcgatatgc tgggcttcag cattatgaag aaagtgtctg gtaactcgcc ggtgattttc
    21661 gacgtgaccc acgcactgca atgccgcgat ccgtttggcg cagcttccgg tggtcgtcgt
    21721 gctcaggtgg ctgagctggc acgagccggt atggcggtag gtctggcggg gctgtttatt
    21781 gaagcgcatc cggatccgga acatgcgaaa tgtgatggtc catccgcgct gccgctggct
    21841 aaactggaac cgttcctcaa gcagatgaaa gcgattgatg atctggtgaa aggtttcgaa
    21901 gaactggata ccagcaagta atcttttttg cttgaaaaat aaagtattag cgttctgcgt
    21961 taagactttt ttcatgggtg ccggatacaa aaa
//
LOCUS       DACAOP010000079        21973 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.079, whole genome shotgun sequence.
ACCESSION   DACAOP010000079 DACAOP010000000
VERSION     DACAOP010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21973
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.079"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..208)
                     /locus_tag="IT892_003232"
     CDS             complement(<1..208)
                     /locus_tag="IT892_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136418.1"
                     /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT
                     SGHPVNPLLGAKVLPGETDIALPGP"
     gene            complement(411..812)
                     /gene="nikR"
                     /locus_tag="IT892_003233"
     CDS             complement(411..812)
                     /gene="nikR"
                     /locus_tag="IT892_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HAP3136419.1"
                     /translation="MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEA
                     TQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLK
                     GDMGDVQHFADDVIAQRGVRHGHLQCLPKED"
     gene            complement(818..1624)
                     /gene="nikE"
                     /locus_tag="IT892_003234"
     CDS             complement(818..1624)
                     /gene="nikE"
                     /locus_tag="IT892_003234"
                     /EC_number="7.2.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikE"
                     /protein_id="HAP3136420.1"
                     /translation="MTLLNISGLSHHYAHGGFNGKHQHQAVLNNVSLTLKSGETVALL
                     GRSGCGKSTLARLLVGLESPAQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAV
                     NPRKTVREILREPMRHLLSLKKSEQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQRV
                     CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERF
                     CQRVMVMDNGQIVETQVVGEKLTFSSDAGRVLQNAVLPAFPVRRRTTEKV"
     gene            complement(1621..2385)
                     /gene="nikD"
                     /locus_tag="IT892_003235"
     CDS             complement(1621..2385)
                     /gene="nikD"
                     /locus_tag="IT892_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikD"
                     /protein_id="HAP3136421.1"
                     /translation="MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSL
                     TCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHA
                     RETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP
                     FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSDGK
                     IVEQGDVETLFNAPKHTVTRSLVSAHLALYGMELAS"
     gene            complement(2385..3218)
                     /gene="nikC"
                     /locus_tag="IT892_003236"
     CDS             complement(2385..3218)
                     /gene="nikC"
                     /locus_tag="IT892_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikC"
                     /protein_id="HAP3136422.1"
                     /translation="MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSR
                     LLSPDAQHWLGTDHLGRDIFSRLMAATRVSLGSVMACLLLVLTLGLVIGGSAGLIGGR
                     VDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISL
                     RQREFVLASRLSGAGHVRVFVDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVT
                     APTAEWGVMINDARQYIWTQPLQMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHA
                     H"
     gene            complement(3215..4159)
                     /gene="nikB"
                     /locus_tag="IT892_003237"
     CDS             complement(3215..4159)
                     /gene="nikB"
                     /locus_tag="IT892_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikB"
                     /protein_id="HAP3136423.1"
                     /translation="MLRYVLRRFLLLIPMVLAASVIIFLMLRLGTGDPALDYLRLSNL
                     PPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGISFASQRPVLDDMLNFLPATL
                     ELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV
                     YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLDVAGQRHVTWARLRGLND
                     KQTERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPV
                     IQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA"
     gene            complement(4159..5733)
                     /gene="nikA"
                     /locus_tag="IT892_003238"
     CDS             complement(4159..5733)
                     /gene="nikA"
                     /locus_tag="IT892_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HAP3136424.1"
                     /translation="MLSTLRRTLFALLACASFIVHAAAPDEITTAWPVNVGPLNPHLY
                     TPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFD
                     AEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRP
                     FRFIAPSQFKNHETMNGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITF
                     NVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALN
                     TAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPSQYDP
                     QKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGAD
                     VSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADK
                     PLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYA
                     PIATEIPFEQIKPVKP"
     gene            complement(5844..6431)
                     /gene="acpT"
                     /locus_tag="IT892_003239"
     CDS             complement(5844..6431)
                     /gene="acpT"
                     /locus_tag="IT892_003239"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase AcpT"
                     /protein_id="HAP3136425.1"
                     /translation="MYRIVLGKVSTLSAAPLPPGLREQAPQGPRRERWLAGRALLSHT
                     LSPLPEIIYGEQGKPAFAPEMPLWFNLSHSGDDIALLLSDEGEVGCDIEVIRPRANWR
                     WLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQIVSVDSTYHSS
                     LSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN"
     gene            complement(6486..7535)
                     /locus_tag="IT892_003240"
     CDS             complement(6486..7535)
                     /locus_tag="IT892_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP3136426.1"
                     /translation="METPQPDKTGMHILLKLASLVVILAGIHAAADIIVQLLLALFFA
                     IVLNPLVTWFIRRGVQRPVAITIVVVVMLIALTALVGVLAASFNEFISMLPKFNKELT
                     RKLFKLQEMLPFLNLHMSPERMLQRMDSEKVVTFTTALMTGLSGAMASVLLLVMTVVF
                     MLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLELM
                     GVQFALMWAVLAFLLNYVPNIGAVISAVPPMIQVLLFNGVYECILVGALFLVVHMVIG
                     NILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKL
                     AILLGPGRPKSRLPG"
     gene            7667..8884
                     /locus_tag="IT892_003241"
     CDS             7667..8884
                     /locus_tag="IT892_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417930.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136427.1"
                     /translation="MPEPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYV
                     HDVMGFSAFWAGLVISLQYFATLLSRPHAGRYADSLGPKKIVVFGLCGCFLSGLGYLT
                     AGLTASLPVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTY
                     GAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLG
                     RVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGIN
                     RIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFPALGVVAVKAVP
                     QQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVAIALLLTWRLKK
                     RPPEHVPEAASSS"
     gene            complement(8888..9445)
                     /gene="dcrB"
                     /locus_tag="IT892_003242"
     CDS             complement(8888..9445)
                     /gene="dcrB"
                     /locus_tag="IT892_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417929.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage sensitivity protein DcrB"
                     /protein_id="HAP3136428.1"
                     /translation="MRNLVKYVGIGLLVMGLAACDDKDTNATAQGSVAESNATGNPVN
                     LLDGKLSFSLPADMTDQSGKLGTQANNMHVWSDATGQKAVIVIMGDDPKEDLAVLAKR
                     LEDQQRSRDPQLQVVTNKAIELKGHKMQQLDSIISAKGQTAYSSVILGNVGNQLLTMQ
                     ITLPADDQQKAQTTAENIINTLVIQ"
     gene            complement(9518..10183)
                     /locus_tag="IT892_003243"
     CDS             complement(9518..10183)
                     /locus_tag="IT892_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HAP3136429.1"
                     /translation="MNVFSQTQRYKALFWLSLFHLLVITSSNYLVQLPVSILGFHTTW
                     GAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLISYVISSLFYMGSWQGFGALA
                     HFNLFVARIATASFMAYALGQILDVHVFNRLRQSRRWWLAPTASTLFGNVSDTLAFFF
                     IAFWRSPDAFMAEHWMEIALVDYCFKVLISIVFFLPMYGVLLNMLLKRLADKSEINAL
                     QAS"
     gene            10404..10649
                     /gene="tusA"
                     /locus_tag="IT892_003244"
     CDS             10404..10649
                     /gene="tusA"
                     /locus_tag="IT892_003244"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HAP3136430.1"
                     /translation="MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIAD
                     DPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG"
     gene            complement(10751..12949)
                     /gene="zntA"
                     /locus_tag="IT892_003245"
     CDS             complement(10751..12949)
                     /gene="zntA"
                     /locus_tag="IT892_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /protein_id="HAP3136431.1"
                     /translation="MSTPDNHGKKAPQFAAFKPLTTVQNANDCCCDGACSSTPTLSEN
                     VSGTRYSWKVSGMDCAACARKVENAVRQLAGVNQVQVLFATEKLVVDADNDIRAQVES
                     ALQKAGYSLRDEQAAEEPQASRLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATT
                     LVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEG
                     WAASRARQGVSALMALKPETATRLRKGEREEVAINSLRPGDVIEVAAGGRLPADGKLL
                     SPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIE
                     EAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGC
                     PCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTA
                     IHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEA
                     QVNGERVLICAAGKHPADAFTGLINELESAGQTVVLVVRNDDVLGVIALQDTLRADAA
                     TAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTELNQHAPLA
                     MVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANI
                     RQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLRRR"
     gene            complement(13023..13649)
                     /locus_tag="IT892_003246"
     CDS             complement(13023..13649)
                     /locus_tag="IT892_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysoplasmalogenase"
                     /protein_id="HAP3136432.1"
                     /translation="MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQ
                     APMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSF
                     FWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALS
                     AFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL"
     gene            13790..14149
                     /locus_tag="IT892_003247"
     CDS             13790..14149
                     /locus_tag="IT892_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HAP3136433.1"
                     /translation="MSKPPLFFIVIIGLIVVAASFRFMQQRREKADNDMAPLQQKLVV
                     VSNKREKPINDRRSRQQEVTPAGTSIRYEASFKPQSGGMEQTFRLDAQQYHALTVGDK
                     GTLSYKGTRFVSFVGEQ"
     gene            complement(14152..14421)
                     /locus_tag="IT892_003248"
     CDS             complement(14152..14421)
                     /locus_tag="IT892_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1145 family protein"
                     /protein_id="HAP3136434.1"
                     /translation="MLINIGRLLMLCVWGFLILNLVHPFPRPLNIFVNVALIFTVLMH
                     GMQLALLKSTLPKDGPQMTTAEKVRIFLFGVFELLAWQKKFKVKK"
     gene            complement(14411..15007)
                     /gene="rsmD"
                     /locus_tag="IT892_003249"
     CDS             complement(14411..15007)
                     /gene="rsmD"
                     /locus_tag="IT892_003249"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /protein_id="HAP3136435.1"
                     /translation="MKKPNHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLF
                     NWLAPVIVDAQCLDCFAGSGALGLEALSRYAAGATLIEMDRAVSQQLIKNLATLKAGN
                     ARVVNSNAMSFLAQKGTPHNIVFVDPPFRRGLLEETINLLEDNGWLADEALIYVESEV
                     ENGLPTVPANWSLHREKVAGQVAYRLYQREAQGESDAD"
     gene            15157..16650
                     /gene="ftsY"
                     /locus_tag="IT892_003250"
     CDS             15157..16650
                     /gene="ftsY"
                     /locus_tag="IT892_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAP3136436.1"
                     /translation="MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEP
                     VKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETP
                     EPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELETALA
                     AEAAEEAVMVVPPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLF
                     RGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMG
                     EILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRA
                     AAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSH
                     LMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDG
                     TAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED"
     gene            16653..17321
                     /gene="ftsE"
                     /locus_tag="IT892_003251"
     CDS             16653..17321
                     /gene="ftsE"
                     /locus_tag="IT892_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAP3136437.1"
                     /translation="MIRFEHVSKAYLGGRQALQGVTFHMQPGEMAFLTGHSGAGKSTL
                     LKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAI
                     PLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL
                     ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDINLISRRSYRMLTLSDGHLHGG
                     VGHE"
     gene            17314..18372
                     /gene="ftsX"
                     /locus_tag="IT892_003252"
     CDS             17314..18372
                     /gene="ftsX"
                     /locus_tag="IT892_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HAP3136438.1"
                     /translation="MNKRDAINHIRQFGGRLDRFRKSVGGSGDGGRNAPKRAKSSPKP
                     VNRKTNVFNEQVRYAFHGALQDLKSKPFATFLTVMVIAISLTLPSVCYMVYKNVNQAA
                     TQYYPSPQITVYLQKTLDDDAAAGVVAQLQAEQGVEKVNYLSREDALGEFRNWSGFGG
                     ALDMLEENPLPAVAVVIPKLDFQGTESLNTLRDRITQINGIDEVRMDDSWFARLAALT
                     GLVGRVSAMIGVLMVAAVFLVIGNSVRLSIFARRDSINVQKLIGATDGFILRPFLYGG
                     ALLGFSGALLSLILSEILVLRLSSAVAEVAQVFGTKFDINGLSFDECLLLLLVCSMIG
                     WVAAWLATVQHLRHFTPE"
     gene            18617..19471
                     /gene="rpoH"
                     /locus_tag="IT892_003253"
     CDS             18617..19471
                     /gene="rpoH"
                     /locus_tag="IT892_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007899894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HAP3136439.1"
                     /translation="MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYH
                     GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLV
                     SFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
                     LGVTSKDVREMESRMAAQDMTFDLSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWE
                     EQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMK
                     KLRAAIEA"
     gene            19742..20845
                     /locus_tag="IT892_003254"
     CDS             19742..20845
                     /locus_tag="IT892_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     substrate-binding protein"
                     /protein_id="HAP3136440.1"
                     /translation="MNIKGKALLAGCIALAFSNMALAEDIKVAVVGAMSGPVAQYGDQ
                     EFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVAVANKVVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGLDSDQGPTAAKYILEKVK
                     PQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEKDFSTLVARLKKENID
                     FVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGESAEGLLVTKPKNYD
                     QVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQSDDPAEIAKYLKANSVDT
                     VMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK"
     gene            complement(21033..21416)
                     /gene="panM"
                     /locus_tag="IT892_003255"
     CDS             complement(21033..21416)
                     /gene="panM"
                     /locus_tag="IT892_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /protein_id="HAP3136441.1"
                     /translation="MKLTIIRLEKFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARF
                     NERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRNNPGVSCWWMADAGV
                     EDRGVMTAFMQALGFTAQQGGWEKC"
     gene            21840..>21973
                     /locus_tag="IT892_003256"
     CDS             21840..>21973
                     /locus_tag="IT892_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417915.1"
                     /note="with LivFGHM is involved in the high affinity
                     leucine transport; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine ABC transporter subunit
                     substrate-binding protein LivK"
                     /protein_id="HAP3136442.1"
                     /translation="MKRNAKTIIAGMIALAISHTAMADDIKVAVVGAMSGPIAQWGDM
                     "
BASE COUNT         5253 a         5771 c         6062 g         4887 t
ORIGIN      
        1 gcgggccggg cagggcgatg tcggtttcac cgggaaggac ctttgcaccg agcaggggat
       61 tgaccggatg gccggacgtc actccgccgg ggcacaccga acaggccacg ccggtggggg
      121 caccaatgcg caccccggct gaaccctgaa caatgctacc gccatactgc gtcatgtcgc
      181 cctgacgcgc cgccggtttt ccgctcatcg taaaatcctt ttctattatt ttaatgacag
      241 tatcttcata cgaaaaagcg aagaaaaact tgtggtcaca atgaattgaa gatttttagg
      301 aatatattta gaacgttaca aaagagaagg ttcggatagg gtatttagag aggaatcagg
      361 tgtgctagtg gccctttgtt gatcgttcac caaaggaccc aataatagac tcaatcttcc
      421 ttcggcaagc actgcaaatg cccgtgccgc acgccgcgct gggcgataac gtcatcggca
      481 aaatgctgca cgtcacccat gtcacctttc aacacggcga tttccagaca gtcgtcgtgg
      541 ttgatgtgca catgcagcgt ggcgacggag aggtcgtggt gatgatgctg ggtggagaca
      601 atgcggctgg ctaagtcgcg tttttcgtgt tcatacacat acgacagcac cgcgaaacct
      661 tgcgtgccgt gctgctgggt ggcctcttgc gccagggcgc tacgcagaat gtcgcggata
      721 gcttcggaac ggttgttata accacgacgc tggctcaggc tgtccagcgt ctccagtaaa
      781 tcgtcatcaa gcgtgatggt gactcgttgc atttgcgtta aaccttttct gtggtgcgac
      841 ggcgcacggg gaatgcgggt aataccgcgt tttgtagcac acgtccggcg tcagaggaaa
      901 aggttaattt ctctcccacc acctgggttt cgacgatttg tccgttgtcc ataaccatta
      961 cccgctggca aaagcgttct accaggcgta agtcgtgggt gatgaacagg caggcggtgc
     1021 caaactgttg ttgtagcttt ttcagcaggc gaatgacacc cgcctgtaac acgagatcaa
     1081 ggttagaaac ggcttcatcc agaatcagta gtttcggttc gaccgccagc gcgcgagcca
     1141 ggcagacgcg ctggagctgg ccgccgctta actgcggtgg gcgtttgtcg agaacgctgt
     1201 catcgagatc gaccgccttc agcatttcgc tggcgcgcgc cagttgttcg gattttttca
     1261 gtgatagcag gtggcgcatc ggttcacgca ggatctcgcg cacggttttg cgcggattca
     1321 cggcgctgat ggagtcctga aataccatct gaatatcgcg gcggaacgct ttacgctggg
     1381 cgcgattgag tttcgccagc ggttcgccac gccagctaat attcccctgc gcgggcgatt
     1441 ctaaacccac cagcaaccgc gcgagggtac ttttcccgca gccgctgcgc cccagcaggg
     1501 cgacggtttc gccgcttttc agggtcaggg aaacgttatt cagcaccgcc tgatgttgat
     1561 gttttccgtt aaatccaccg tgcgcatagt gatgggaaag gccggagatg ttaagtaaag
     1621 tcatgatgcc agctccatac cgtagagggc gagatgagcg gaaaccaggc tgcgcgtcac
     1681 tgtatgtttg ggggcgttaa acagcgtttc tacatcgccc tgttcgacaa tcttaccgtc
     1741 agacatcacc gccacgtcat ccgccagacg cgccacaacg cccatatcat gggtcaccag
     1801 cagcattccc ggcgcttgtt tttgcataat gctttccagc agatcgagga tgcgcgcctg
     1861 tgctaccacg tcaaggtcgg tggtcggttc atcggcgatg ataaacggtg attcacacag
     1921 caccgccatc gcaatcatca tgcgctgcaa catgccgccg ctcatctcga acgggtacag
     1981 cttcagcacg cgcgcggcgt tttccagccc caccgcttct atggcagcgg taagcgtagc
     2041 gtcatcggcg ggtttcccta acgccaggca ggtttcccgc gcgtgggtgt gcatggtgtg
     2101 cagtggatta aaggcgctgc gcgggttctg catgatggtg gcaattttga tgccgcgcag
     2161 ggcgcaaggc gaaaccggtt tgccatcggc taaaatttcc cccgccgtct ggcgaacgcc
     2221 agcgggcaaa atgcccagcg tcgcggcgca ggttaatgat ttcccgctgc cgctaccgcc
     2281 gactaacgcc agcacgcgcc cgcgttgcag ggttaacgat acaccgtgta ccagcggctg
     2341 cgcggcctgt agcgcgatat tacgtagttc aatctgttgc ggcattagtg tgcgtgctcc
     2401 gtcaccagat gagggtccag atgatcgcgc agtgcgtcac ccaccaggtt aaaggccatc
     2461 acgctgataa acagcgccag ccccggccag aacatttgca gcggctgggt ccagatatac
     2521 tggcgcgcgt cgttaatcat cacgccccat tcggcggtcg gcgcggtcac accgaggcca
     2581 aggaaagaca tccccgcgac gtgcagcatc atatggccga tatccagcgt tgccagcacc
     2641 agcagcgaag ggatcaccgc gcctgccaga tgatcgacaa acacccgcac atggcccgca
     2701 ccggaaagcc gtgacgccag cacaaactcg cgttggcgta gtgaaatcac caggctgcgc
     2761 accatgcgtg cataccacgc ccagtgcgac agggcgatgg cgataattac gttggtcagc
     2821 ccggtgccga gcacgccaac cataaagaac gacagaatcg aggtcgggaa ggtcataaac
     2881 atatcggcga cgcgcatggt ggcctgatca acgcgcccgc caatcaaccc ggcgctgccg
     2941 ccaataacca gccctaatgt cagcaccagc agcaggcagg ccattaccga accgagcgac
     3001 acgcgggtcg ctgccatcag ccgcgagaaa atatcgcgac ctaagtgatc ggtgcccagc
     3061 cagtgctgcg catccggcga aagcaggcgc gacggcaaat caatcgcctg ggggtcatac
     3121 ggcagccacc actggctggt gagcgcaatc agcgccagca gggcgataat gatcagcgcc
     3181 aggcgtaccg accagcggga agagaggaaa aagttcacgc gtgcgctcct tcatgacgac
     3241 gaatgcgcgg gtccagcgcg gcgttgagca aatcgacaat caaattacag accacaaaaa
     3301 ccaccaccat catcagcgta aagcactgga tcaccggata gtcacggtta aaaatcgccg
     3361 acaccgcata gcgcccgacg cccggccagg caaagatgtt ttcgataatc atcgtcccgc
     3421 caatcagttc gccgatatgc atccccacgg cggtgatcat cggcagcgag gcattgcgca
     3481 ggatgtggcg acgttcggtc tgtttgtcgt tcaggccgcg cagacgcgcc caggtgacgt
     3541 gacgctgacc ggcgacgtcc agcatactgg cgcgcagtaa acgcgcgtta atcgccagcg
     3601 acataaaggc aatggaaacc gcaggcaaaa tgatgtgctg ccagccgccg taacccatcg
     3661 cgggtagcca ttgcagatac accgaaaacg ccatcaccag taaaaacgcc agccagaagt
     3721 taggcatcga cacgccaaga aacgcgatga aacgtacggc gaaatccggc agacggtcgc
     3781 gatggcgcgc cgcccagata ccgagcggta cggaagtgag cagaattaat accagcgccg
     3841 cacctgcaag ttccagcgtg gcgggcagga agttcagcat atcgtccagt accgggcgtt
     3901 ggctggcgaa tgagatacca aagtcaagat gcagcgcctt ccacaaccag gtgccgtact
     3961 ggacgtacag cggctgatcc agtcccagca tggtgcgggt agaggccagc atctccggcg
     4021 tcggcggcag gttagacaga cgcaaataat cgagcgccgg gtcgccggta ccgaggcgca
     4081 gcatcagaaa aatgatcacc gaggcggcga gcaccatcgg gatcagcagc agaaagcggc
     4141 gtaatacgta acgcaacatt aaggtttcac cggtttaatc tgttcgaacg gaatttcggt
     4201 ggcgatcggc gcgtagggga tgttacccag ctccggtttt gataccacca tcattgagat
     4261 gtaactgata ggcagataaa ccgcctcgtc atgcagacgg gtcagaatgt cgcgatacag
     4321 cgcctgacgt tgcgtttcgt catgggtcgc cagcacttcg ccgatctctt tatcaatcag
     4381 cggtttgtcg gctaatcctt gctgtgcctg gaagtcagcg tgtgacggta cgcgcattga
     4441 actgaggaag gcgtgtggat catatggcgc gccccaggtg cggtggaaaa tcatgccaaa
     4501 acgaccgtcg cgctgacgag catagatact gctctcttct tcgccaatca gcgagacatc
     4561 tgcgccaatc tggcgcatat cagcctgaat gatttccgcc atcgatttgc ttaacgcatc
     4621 ggtgccgatg aacgaaagtt caatgcgcag cggctgacca tttttctcgc ggatgtcttt
     4681 gcccgcaggc agcgtccaac cggctttttc cagcaacgct ttcgcttttt gcggatcgta
     4741 ctggctcggt ttcaggccga ggttggcgta gggcacagaa ggggcaaaca gggtgtcggc
     4801 gacctgctgg gtgccataca acgcgttatc aatcagcgat tttttgttta ccgcgtaatt
     4861 aagagcttca cgtactgcca gctcgttggt gggggctttg gcggtattga gcgccagcat
     4921 cacggtttcg atcggctgtg acagttgggt gtggtaagcc ggattctggc taaagcgggc
     4981 gaaggtatcg agcggtaata acccttcgtt tccgtacagc aggtcgatat cgccagtttc
     5041 aaacgccacc gcgcgggtag tcgggtccgg gatgacgtta aaggtgatct ttttaatcgc
     5101 tggcttttcg ccccagtagt tttcgttacg gacgaagaca tcgtactgat tcagtttcga
     5161 ttcctgcaaa atccacggtc cggtgccaat cggcgcttta attccgttca tggtttcatg
     5221 gtttttaaac tgcgagggag cgataaaacg gaaaggacgg ggcagggcca gttcttgcag
     5281 gaaaggatag taggcgcttt tcagggtaat ttgcagctct gttttactga gtgctttaac
     5341 atcaacaatc tggtttgcca gctccagcca ggcgtgacgt tgacggttat cgagcactgc
     5401 gcggaagttt tctgccgccg cctcggcatc gaacggttca ccgttggaga atttcacgtc
     5461 atcacgcagg gtgaaggtcc aggttttacc atcttctgaa tgagtccagc tttttgccag
     5521 ccacgggatc accgaaccgt ctgcctgata tttcaccaat ggttcataaa ccatgctctg
     5581 ggcgaacatc tggttaggcg tgtaaaggtg cgggtttagt ggcccgacat tcaccggcca
     5641 ggcggtggtg atttcatctg gtgcagcggc atggacgata aaagacgcac aagccagcag
     5701 cgcaaataga gtgcggcgga gtgtggagag catggtaacc ccaatggatt aaaatagatg
     5761 gcggaaataa gtatgacgat tttaagtatt cgtcatactg attacctgtt ctggatcaat
     5821 agatgggcag tcgggtgggc ggatcagtta actgaatcga tccattgcac actgtcggcg
     5881 gtgagcgtaa agggagtagg ggtgcagatc gcaaggctta aattttcaag ctgacaatgg
     5941 ctgactgaca gcgaggagtg ataggtgctg tctacgctga cgatttgcca ggcgctgccg
     6001 ccacgctgtt taacgatggc ttctttgcgc gtccagatgc gccagaacat ttccagttgc
     6061 tgatcaggat gcacggcgtc catctcagcg tgttccccga ggctgaatac ggcgttcgcc
     6121 agccagcgcc agttggcgcg cgggcgaatc acttcgatat cgcagccgac ttcgccttca
     6181 tcactcaaca gcagggcgat atcgtcaccg ctatggctta agttgaacca tagcggcatt
     6241 tccggcgcaa atgcaggttt gccttgttcg ccatagatga tctccggtag cggggaaagc
     6301 gtgtgcgaaa gcaatgcacg ccccgccagc cagcgttcgc gtcgtggacc ttgcggtgct
     6361 tgctcgcgta aacccggtgg cagtggagct gcgcttaagg tcgaaacttt ccccagaact
     6421 atccgataca tatcagggcc aacgtttaat ggaaaatgaa agtgcgtatc gtatcacttg
     6481 tcgcctcatc ccggtaaccg acttttcggt ctgcccggcc ccagtaaaat cgccagtttg
     6541 ctaccgcctt tggtggtttc catccagatt ttacacacgc tggttaatgg caccgaaagt
     6601 agcatcccta ccgggccgag cagccatccc caaattaaca atgaaagaaa taccaccatg
     6661 gtggacatcc ccaggcgatg gcccatcatc cgtggttcta aaatattgcc gatgaccata
     6721 tggaccacta aaaacaatgc gccgaccaga atacattcgt aaacaccatt aaacagcagc
     6781 acctgaatca ttggcggtac ggcggaaatt accgcgccga tattgggcac gtagttgagc
     6841 aaaaacgcca gtactgccca catcagcgca aactgcaccc ccatcagctc cagccccagc
     6901 cagacgatga cacctgtcca taaactgagt agcgtcttca atgcaagata gtgcgaaacg
     6961 cctttaagtg cgcggtgtaa tcccgcgatg tgaatctgtg gattattcag cgcaaaacgc
     7021 attttgtaag ggacgtggcg cacttcaaac agcataaaaa ctacggtcat caccagcaaa
     7081 agcacgctcg ccattgcccc ggaaagcccg gtcattagcg ctgtggtgaa ggtaaccact
     7141 ttttccgagt ccatccgctg cagcattcgc tccggcgaca tatgcaaatt aagaaaaggc
     7201 aacatctcct gcaatttaaa aagtttgcgc gtcagctcct tattaaactt cggcagcata
     7261 gagataaatt cgttaaacga tgccgccagt acgccgacca gcgcggttag tgcgatcagc
     7321 atcaccacca ctacaatcgt aatggcaacg gggcgttgta ctccccgacg aataaaccag
     7381 gtgacgagcg ggttgaggac gatggcaaaa aacagcgcca gtaacagctg cacaatgata
     7441 tctgccgctg cgtgaatgcc cgcgaggatc actaccagcg aggccagctt gagcagaatg
     7501 tgcatgcccg ttttatcggg ttgaggggtt tccattgggg cttccttgtg actttttgta
     7561 ttaagtgtag cgggagtcac gccagcaata ttctgattct tactgctgat tttcacgtca
     7621 gcacgtggta aaaatgaaac actgttgtaa aaatgtggtg atcctcatgc ccgaacccgt
     7681 agccgaaccc gcgctaaacg gattgcgcct gaatttgcgc attgtctcta tagtcatgtt
     7741 taacttcgcc agctacctca ccatcgggtt gccgctcgct gtattaccgg gctatgtcca
     7801 tgatgtgatg ggctttagcg ccttctgggc aggattggtt atcagcctgc aatatttcgc
     7861 caccttgctg agccgccctc atgccggacg ttacgccgat tcgctgggac ccaaaaagat
     7921 tgtcgtcttc ggtttatgcg gctgcttttt gagcggtctg gggtatctga cggcaggatt
     7981 aaccgccagt ctgcctgtca tcagcctgtt attactttgc ctggggcgcg tcatccttgg
     8041 gattgggcaa agttttgccg gaacgggatc gaccctatgg ggcgttggcg tggttggctc
     8101 gctgcatatc gggcgggtga tttcgtggaa cggcattgtc acttacgggg cgatggcgat
     8161 gggtgcgccg ttaggcgtcg tgttttatca ctggggcggc ttgcaggcgt tagcgttaat
     8221 cattatgggc gtggcgctgg tggccatttt gttggcgatc ccgcgtccga cggtaaaagc
     8281 cagtaaaggc aaaccgctgc cgtttcgcgc ggtgcttggg cgcgtctggc tgtacggtat
     8341 ggcgctggca ctggcttccg ccggatttgg cgtcatcgcc acctttatca cgctgtttta
     8401 tgacgctaaa ggttgggacg gtgcggcttt cgcgctgacg ctgtttagct gtgcgtttgt
     8461 cggtacgcgt ttgttattcc ctaacggcat taaccgtatc ggtggcttaa acgtagcgat
     8521 gatttgcttt agcgttgaga taatcggcct gctactggtt ggcgtggcga ctatgccgtg
     8581 gatggcgaaa atcggcgtct tactggcggg ggccgggttt tcgctggtgt tcccggcatt
     8641 gggtgtagtg gcggtaaaag cggttccgca gcaaaatcag ggggcggcgc tggcaactta
     8701 caccgtattt atggatttat cgcttggcgt gactggacca ctggctgggc tggtgatgag
     8761 ctgggcgggc gtaccggtga tttatctggc ggcggcggga ctggtcgcaa tcgcgttatt
     8821 actgacgtgg cgattaaaaa aacggcctcc ggaacacgtc cctgaggccg cctcatcatc
     8881 ttaaaactta ctgaataacc agcgtattaa tgatgttttc tgcggtggtc tgcgcttttt
     8941 gctgatcgtc agcgggcagc gtaatttgca tggtcagcag ttgattaccc acgttaccca
     9001 gaataacgga agagtacgcc gtctggcctt tcgcggagat aatactgtct aactgctgca
     9061 ttttgtgacc tttcagctca atggctttat tggttaccac ttgcagctgc ggatcgcggc
     9121 tacgttgctg atcttccaga cgcttcgcca gcaccgccag atcttctttc ggatcatcgc
     9181 ccatgatgac gatgactgct ttctgcccgg tggcgtcgga ccagacatgc atgttattgg
     9241 cctgcgttcc cagcttaccg ctctggtcgg tcatatccgc tggcagcgag aaacttaact
     9301 tgccatcaag caggttgacg ggattcccgg tagcgttact ttccgcgacc gaaccctgcg
     9361 ccgtagcgtt agtgtcttta tcatcacagg ccgcaagccc cataaccagc aggccaattc
     9421 cgacatattt aaccagattg cgcattgact tcttcctttc gataaacggc cataacggct
     9481 cattcatcca tcttatcaca actctgataa cgaaccttta actcgcctgc aaagcgttga
     9541 tttcggattt atctgccagt cttttcaaca gcatattgag taatacgcca tacattggca
     9601 ggaagaaaac gatactgatt aacactttga aacagtaatc gaccagcgcg atttccatcc
     9661 agtgttcagc cataaaggca tccgggctac gccagaaggc aatgaagaaa aaggccagcg
     9721 tgtcgctgac gttaccgaac agtgtggacg ctgtcggtgc cagccaccag cggcgactct
     9781 gacgcaggcg gttaaaaacg tgcacgtcga ggatttgccc cagcgcgtag gccatgaaac
     9841 tggcggtggc gatacgggcg acaaacaggt tgaagtgggc gagtgcgccg aatccctgcc
     9901 aggaacccat atagaatagc gacgagatga cgtaggagat taataacgca gggatcatta
     9961 ccgcgaagat aatgcgtcgg gccagcggtg cgccaaaaat acgcacggtc aggtcggtag
    10021 caagaaaaat aaacggaaag ctaaacgcgc cccaggtggt atggaaaccc aaaatggaga
    10081 cgggaagctg aaccagatag ttactggagg tgatcaccag cagatgaaat aacgataacc
    10141 agaacaacgc cttatagcgt tgagtttgcg agaaaacgtt catattgtac ctttttgatt
    10201 aaccattggg gtgagggaac ccaatacgta cgacacgtct gttaccttaa cataataacg
    10261 tgcttaccct tttttcgagc cgccgcatga tactgcttta cgttgacaat gcaatggtta
    10321 attttcacgc aatcgttaac ctagtttgct tacggactca cagggcgtaa actagcgccg
    10381 tttttttaag tgatgagaag aaaatgaccg atctcttttc cagccctgac cacacactcg
    10441 acgcgcttgg cctgcgctgc ccggaaccgg tgatgatggt gcgcaaaacc gtgcgcaata
    10501 tgcagcctgg cgaaacgttg ctgattatcg ccgacgatcc ggccactacc cgcgatattc
    10561 ctgggttttg tacctttatg gaacacgaac tggttgctaa agagacggat ggactgcctt
    10621 atcgttattt gattcgtaaa ggcggttgat aggggctgat tggcttcgat gccgcctttt
    10681 cccctcaccc taaccctctc cccagagggg cgaggggacc gatcgcgctc aatgttgcga
    10741 tcggtttgcc ttatctcctg cgcaacaatc ttaacgcatt cgctgtcacc agcaccgtcg
    10801 cccccgtatc tgccagcact gccagccaca acccggtcat ccctaacagc gtggtgacga
    10861 ggaagatccc tttcagcccc agcgcaatag tgatgttctg gcggatattg gcgtgagtgg
    10921 cgcgtgccag ttcaatcatt tgcaccaggc cgcgcaggtg gttatgggtt aatgctgcgt
    10981 cggcggtttc cagcgccacg tctgtgccgc tacccattgc aatcccgatg gcggcagctt
    11041 tcatcgctgg cgcgtcgtta ataccgtcac cgaccatcgc cagcggcgca tgttgattca
    11101 gctcggtcac cgctttgact ttatcttccg gcaacaggcc cgctttaaac tccagcccca
    11161 gctccccggc aattgccgcc gctgcgcgtg gattatcgcc ggtgaggatc acccctttga
    11221 cgcccagcgc gttcagttca ctgatggcag ttgcagcatc ggcgcgcagg gtatcctgta
    11281 acgcaatgac accaagcacg tcatcgttac gtactaccag cactaccgtt tgcccggcgc
    11341 tttccagttc gttaattaaa ccagtaaatg catcagcggg atgtttcccg gcagcgcaaa
    11401 tcaatacgcg ctcaccgtta acctgcgctt caatgccaga cccgaccagc gcccgctgtg
    11461 attcggcggt gggaatggcg agttcagcaa cctgtgcttc gcgtacgatg gcttgcgcca
    11521 gtggatgcgt cgcgccttgc tcgaccgccg ccgccagtgt cagcagttca gattcactaa
    11581 tacccgttgc cggatgaatc gcggtaacgc gcggtttacc gacggtcagc gtaccggttt
    11641 tatcaaacgc cacctgagta acacgaccca gctgttccag cgccgctccg cctttaatca
    11701 acgccccacg acgcgctgcc gccgccagcc cggaggtaat cgccgcaggc gttgagataa
    11761 ctaacgcaca cgggcagcca atcagcagca gcgtcagccc tttataaatc cactcctgcc
    11821 agctggcggc aaacagcagc ggtggcacca gcgtcaccag cagagcgacg gccataatcg
    11881 cgggcgtata gatacggctg aaacggtcga taaaccgctc aatgggagcg cgacgctctt
    11941 cggcttcttc gatcagtttc agaatccggt caatggcgct ggctcccggt tctgacagca
    12001 cttccaacgt caccagacgg tctacgctgg tggcaccagc agggacttta tcgcccgttg
    12061 cgcgctccac cggaatggat tcgccggtca gggcgctttc atcaaaactg gcaaacggtg
    12121 agagcagttt accgtcggca ggcaaacgcc cacctgcggc gacttcaatc acatcgccag
    12181 ggcgcaggct gttaatcgcc acctcttccc gctcaccctt acgcaggcgc gtggcggttt
    12241 ctggtttcag cgccattaac gcgctaacgc cctgacgcgc gcggctggcg gcccagcctt
    12301 ccagtcgttc accaatcaaa aacagcagca acaccatcgc agcttcagcc gttgcgccaa
    12361 taaacagtgc accaatagcg gctacgctca ttaaggtttc aatggcgaag tagctgccgg
    12421 atttgatcaa ccgtaatgcc tgacgagcaa tcgggtacag cccaaccagc gtggtcgcga
    12481 taaacgccag ttgcccgaac ggatgattga actgctccag accccagctg attgccatca
    12541 tcacgattag cgtaatcagc ggcagattct ctttcaggcg tgatgcttgc ggttcttcgg
    12601 cggcctgttc atcgcgcagg gaatagcctg ctttttgcag cgcagattca acttgtgcac
    12661 gaatgtcatt gtcggcatcg accaccagtt tttcggtggc gaacaacacc tgcacctgat
    12721 tcacgcctgc aagctggcgc acggcatttt ctaccttgcg cgcacaggcg gcgcagtcca
    12781 tgccgctgac tttccagcta tagcgggtgc cggagacgtt ttcagagaga gttggcgtgc
    12841 tggaacatgc gccgtcgcag caacagtcgt tggcgttctg taccgtggtt agcggtttga
    12901 acgcagcaaa ttgaggggct ttcttgccgt gattgtcagg agtcgacatg gcatcctccg
    12961 gttaagtttt ttctcattaa ccgaaggata cactctggag tcgactccag agtcaagttt
    13021 tatcagagat acagcgagcg gacgatcagg aagtgaccgg caaagtagca ggccgcagca
    13081 atcgcgttat ccgcacggaa gcgtcggcga tagtggctcc ccagccagac aaagttactg
    13141 ataaacagca acgaagcgcc aacaaacgca gagagcgccg gagcggtcgg acggaagaac
    13201 cacagttcac ctgccagcca caccatcacc agcgtcatgc cgataaacgt gcagataggc
    13261 caacggtact cttccaggcg cgtccagata atcgccagta acagcgcacc cagaaccagc
    13321 agcaccagtg gtagaggcca gaagaaagag agcgtcatct gactggcgaa atagatggtg
    13381 tacagcaagt gcgagaggaa aaacgcgccg atggcgtaca tcagacgttg acgtggcaac
    13441 agggttagcg catcgcccag cagtgaggcg cacagccctg ccagcaccag atagctaatg
    13501 gcgtcgaaca tcggcgcttg ccaggccagt aacagcagga gaagaagggt taacggttta
    13561 aacacccagc gttgccaggt tggcccacga tacgatgcat ccacagatag ccatgcggaa
    13621 agacagacag cgataaacga ccaaagcatc ttagttcctt gaattcgtta ttttttcgta
    13681 agcggaatgc ctacggtctt gcttccagtt tagtggcgag ggtggacgga tgacaacacc
    13741 ataactggca gggtatgctt atttccgcat tttccgatga gggataaaga tgagcaaacc
    13801 acctcttttc tttattgtta tcattggctt aattgtcgtc gccgcatcgt ttcgttttat
    13861 gcaacagcga cgggaaaaag ctgataatga tatggctccg ctccagcaaa agctggtggt
    13921 ggtgagcaac aagcgggaaa aaccgattaa cgatcgccgt tcgcgccagc aggaagtgac
    13981 tccggcaggc accagtatac gctatgaggc aagcttcaaa ccgcaaagcg gaggaatgga
    14041 gcagacgttt cgcctcgacg cccagcagta ccacgccctg acagtgggcg ataaaggtac
    14101 gctgagctat aaaggaacgc gctttgtcag ctttgtaggc gaacaataag gttatttttt
    14161 aactttaaat ttcttctgcc aggccagcag ttcaaacacg ccgaaaagga aaatccgtac
    14221 cttttcggcg gtggtcatct gcgggccatc tttcggtaaa gtggatttca atagcgccag
    14281 ctgcatacca tgcatcagca cggtaaaaat cagcgccacg ttaacgaaga tattcagcgg
    14341 gcgtgggaag ggatgcacca ggttgaggat taaaaatccc caaacgcaga gcattaacaa
    14401 acgaccaata ttaatcagca tcactttctc cttgtgcttc gcgttgatac agccgataag
    14461 ccacctgacc cgccactttt tcccgatgta atgaccagtt tgctggaaca gtgggcagac
    14521 cgttttcgac ttcgctttcg acataaatca gggcttcgtc agccagccag ccgttatctt
    14581 ccagtaaatt tatcgtctct tctaacaagc cacggcggaa cggtggatcg acaaacacga
    14641 tattatgcgg tgtacctttt tgcgccagga atgacatcgc gttgctgttc accacgcgtg
    14701 cattgcctgc ttttagtgtc gccagattct taattaactg ctgagaaacc gcgcgatcca
    14761 tctcaatcaa cgttgccccc gcagcgtagc gcgataacgc ttccagcccc agcgcgccgc
    14821 tcccggcgaa gcaatccaga cattgggcgt caacaatgac cggagccagc cagttaaaca
    14881 acgtttcgcg tacgcggtcg gtggtggggc gcagacctgg gctatcagga accgggagtt
    14941 tacggcctcg ccactgcccg ccaataatgc ggatttggcc gctgccggaa tgattcggtt
    15001 ttttcatgat aaattgctca atccgccaga taacacatac ttgcaggcgg tgatgtgaat
    15061 taagttaagt gatagactat ttcatcattt ttttagctgc tatgtacata gcgttaacgc
    15121 tgtgccatga agcaacagcg aggagtgtag tcgcaaatgg cgaaagaaaa aaaacgtggc
    15181 tttttttcct ggctgggctt tggtcaaaaa gagcagaccc cggaaaaaga gacagaagtt
    15241 cagaatgaac aaccggttgt agaagaaatc gttcaggcgc aagagcctgt gaaggcctct
    15301 gaacaagccg ttgaagagca gccgcaagcg catactgaag ccgaggcgga aacttttgct
    15361 gccgacgttg tggaagtcac tgaacaggtt gctgaaagtg aaaaagcgca gcctgaagcg
    15421 gaagtcgttg cacagccgga accggtcgta gaagaaacgc cggagccagt ggctatcgaa
    15481 cgtgaagagc tgccgttgcc ggaagacgtc aacgccgaag cggtttcgcc agaagagtgg
    15541 caggctgaag cggaaaccgt agagattgtc gaagcggcgg aagaagaagc ggctaaagaa
    15601 gaaattaccg acgaagagct ggaaacggcg ctggctgccg aagcggcaga agaggcggtg
    15661 atggtggttc ctccggcaga agaagagcag ccggtggaag aaatcgctca ggagcaggaa
    15721 aaaccgacca aagaaggttt tttcgcgcgc ctgaaacgca gcctgttaaa aaccaaagaa
    15781 aatctcggtt ccggatttat cagcctgttc cgcggtaaaa aaatcgacga tgatctgttt
    15841 gaggagctgg aagagcagct tttgatcgcc gatgtgggtg tggaaaccac acgtaaaatt
    15901 atcaccaatc tgacggaagg cgcatcccgc aagcagcttc gtgacgccga ggcgctctat
    15961 ggcctgctga aagaagagat gggcgagatt ctggcgaaag tcgatgagcc gctgaatgtt
    16021 gaaggcaaag cgccgtttgt gatcctgatg gtgggcgtca acggtgtggg taaaaccacg
    16081 acgattggta agctggcgcg tcagtttgag cagcagggta aatcggtgat gctggcggcg
    16141 ggtgatactt tccgtgcagc tgcggttgaa cagcttcagg tctggggtca gcgcaacaat
    16201 attccggtga ttgcccagca taccggggcg gattccgcct ctgttatctt cgacgccatt
    16261 caggcagcta aagcgcgtaa tatcgacgtc ctgattgccg atacagccgg acgcctgcag
    16321 aacaaatcgc acctgatgga agagttgaag aaaatcgtcc gcgtgatgaa gaaactcgac
    16381 gttgaagcgc cgcatgaagt tatgctgact attgatgcca gcaccgggca gaacgcggta
    16441 agccaggcca aactgttcca tgaagccgtt ggcttaaccg gcatcacgct aacgaaactg
    16501 gacggcacgg cgaaaggcgg ggtaattttc tcggtggctg accagtttgg tatccctatc
    16561 cgctacattg gtgtcggcga acgtattgag gatttgcgtc cgtttaaggc ggacgacttt
    16621 atagaggcac tttttgcccg agaggattaa caatgattcg ctttgaacat gtcagcaagg
    16681 cttatctcgg tgggagacag gcgctgcagg gcgttacgtt ccatatgcag ccgggtgaga
    16741 tggcgtttct gaccggtcat tccggcgcag ggaaaagtac cctcctgaag ctgatctgtg
    16801 ggattgagcg gcccagcgcc gggaaaatct ggtttagcgg ccatgacatc acgcgtctga
    16861 aaaaccgtga agttccgttt ctgcgccgcc agattggcat gattttccag gatcaccatc
    16921 tactgatgga ccgtactgtc tacgataacg tggcgatccc gctgattatc gccggtgcca
    16981 gcggtgacga tattcgtcgc cgggtgtcgg cggcgctgga taaagtcggg ctactggaca
    17041 aagcgaagaa cttccctatt cagctttcgg gcggtgaaca acagcgtgtt ggcattgccc
    17101 gcgcggtggt gaacaagccc gcggtactgc tggcggacga accgactggt aacctggacg
    17161 acgcgctgtc ggaaggcatt ttacgtctgt ttgaagagtt taaccgcgtt ggggtaaccg
    17221 tattgatggc aacgcacgac atcaacctga tctcgcggcg ttcctatcgc atgctcaccc
    17281 tgagcgatgg tcacttgcat ggaggcgtgg gccatgaata agcgcgatgc aatcaatcat
    17341 attcggcagt ttggcgggcg tcttgatcgc ttccgtaaat cggtcggcgg ctcaggcgac
    17401 ggcggtcgta acgcaccaaa acgcgcgaaa tcctcgccaa aaccggtaaa tcgcaaaacc
    17461 aacgttttca acgaacaggt gcgctatgcc ttccacggcg cattgcagga tctgaaaagc
    17521 aaaccgttcg ccacgttttt aacggtgatg gttatcgcca tttctctgac gctgcccagc
    17581 gtctgttata tggtgtacaa aaacgttaac caggcggcga cgcagtatta tccgtcaccg
    17641 caaatcactg tttatctgca aaaaacgctg gacgatgacg ctgctgcggg cgtggtggca
    17701 cagttgcagg ccgagcaagg cgtggagaaa gtgaactatc tttctcgtga agacgcactg
    17761 ggtgagttcc gtaactggtc tggttttggt ggtgcgctgg atatgctgga agaaaacccg
    17821 cttccggcag tggcggtggt gatcccgaaa ctcgatttcc aggggacgga atcactgaat
    17881 acgctgcgtg atcgtatcac gcagattaac ggcattgacg aagtgcggat ggatgacagc
    17941 tggtttgccc gtctggcggc gttgaccggg ctggtcgggc gcgtttcggc gatgatcggc
    18001 gtgttgatgg tggcggccgt gttcctcgtc atcggtaaca gtgtgcgtct gagtatcttt
    18061 gctcgccgtg actccattaa cgtacagaaa ctgattggtg cgacagatgg attcatcctg
    18121 cgcccgttcc tgtatggtgg cgcactgctg ggattttctg gcgcattgtt gtcattaatt
    18181 ttgtcagaaa ttctggtgct gcgattgtca tcggcggttg cggaagtggc acaggttttc
    18241 ggaacgaagt ttgatatcaa tggcttatca ttcgatgaat gcctgctatt gctgctggta
    18301 tgctcgatga ttggctgggt ggcagcgtgg cttgccacgg tacaacattt acgccacttt
    18361 acgcctgaat aataaaagcg tgttatactc tttccctgca atgggttccg tagcagggaa
    18421 agagaccccg ttgtctcttc ccggtatttc atctctatgt cacattttgt gcgtaattta
    18481 ttcacaagct tgcattgaac ttgtggataa aatcacggtc tgataaaaca gtgaatgata
    18541 acctcgttgc tcttaagctc tggcacagtt gttgctacca ctgaagcgcc agaagatatc
    18601 gattgagagg atttgaatga ctgacaaaat gcaaagttta gctttagccc cagttggcaa
    18661 cctggattcc tacatccggg cagctaacgc gtggccgatg ttgtcggctg acgaggagcg
    18721 ggcgctggct gaaaagctgc attaccatgg cgatctggaa gcagctaaaa cgctgatcct
    18781 gtctcacctg cggtttgttg ttcatattgc tcgtaattat gcgggctatg gcctgccaca
    18841 ggcggatttg attcaggaag gtaacatcgg cctgatgaaa gcagtgcgcc gtttcaaccc
    18901 ggaagtgggt gtgcgcctgg tctccttcgc cgttcactgg atcaaagcag agatccacga
    18961 atacgttctg cgtaactggc gtatcgtcaa agttgcgacc accaaagcgc agcgcaaact
    19021 gttcttcaac ctgcgtaaaa ccaagcagcg tctgggctgg tttaaccagg atgaagtcga
    19081 aatggtggcc cgtgaactgg gcgtaaccag caaagacgta cgtgagatgg aatcacgtat
    19141 ggcggcacag gacatgacct ttgacctgtc ttccgacgac gattccgaca gccagccgat
    19201 ggctccggtg ctctatctgc aggataaatc atctaacttt gccgacggca ttgaagatga
    19261 taactgggaa gagcaggcgg caaaccgtct gaccgacgcg atgcagggtc tggacgaacg
    19321 cagccaggac atcatccgtg cgcgctggct ggacgaagac aacaagtcca cgttgcagga
    19381 actggctgac cgttacggcg tttccgctga gcgtgtacgc cagctggaaa agaacgcgat
    19441 gaaaaaattg cgtgctgcca ttgaagcgta atttccgcta ttaagcagag aaccctggat
    19501 gagagtccgg ggtttttgtt ttttgggcct ctgtaataat caatttcccc tccggcaaaa
    19561 cgccaatccc cacgcagatt gttaataaac tgtcaaaata gctattccaa tatcataaaa
    19621 atcgggtatg ttttagcaga gtatgctgct aaagcacggg tagtcatgca taaaacgaaa
    19681 taaagtgctg aaaaacaaca tcacaacaca cgtaataacc agaagaatgg ggattctcag
    19741 gatgaacata aagggtaaag cgttactggc aggatgtatc gcgctggcat tcagcaatat
    19801 ggctctggca gaagatatta aagtcgcggt cgtgggcgca atgtccggtc cggttgcgca
    19861 gtacggtgac caggagttta ccggcgcaga gcaggcggtt gcggatatca acgctaaagg
    19921 cggcattaaa ggcaacaaac tgcaaatcgt aaaatatgac gatgcctgtg acccgaaaca
    19981 ggcggttgcg gtggcgaaca aagtcgttaa cgacggcatt aaatatgtga ttggtcacct
    20041 ctgttcttca tcaacgcagc ctgcgtctga catctacgaa gacgaaggca ttttaatgat
    20101 caccccagcg gcaaccgcgc cggagctgac cgcccgtggc tatcagctga tcctgcgcac
    20161 caccggcctg gactccgacc aggggccgac ggcggcgaaa tatattcttg agaaagtgaa
    20221 accgcagcgt attgctatcg ttcacgacaa acagcaatac ggcgaaggtc tggcgcgagc
    20281 ggtgcaggac ggcctgaaga aaggcaatgc aaacgtggtg ttctttgatg gcatcaccgc
    20341 cggggaaaaa gatttctcaa cgctggtggc gcgtctgaaa aaagagaata tcgacttcgt
    20401 ttactacggc ggttatcacc cggaaatggg gcaaatcctg cgtcaggcac gcgcggcagg
    20461 gctgaaaact cagtttatgg ggccggaagg tgtggctaac gtttcgctgt ctaacattgc
    20521 gggcgaatca gcggaagggc tgctggtgac caagccgaag aactacgatc aggttccggc
    20581 gaacaaaccc attgttgacg cgatcaaagc gaaaaaacag gacccaagtg gcgcattcgt
    20641 ttggaccacc tacgccgcgc tgcaatcttt gcaggcgggc ctgaatcagt ctgacgatcc
    20701 ggctgaaatc gccaaatacc tgaaagcgaa ctccgtggat accgtaatgg gaccgctgac
    20761 ctgggatgag aaaggcgatc tgaaaggctt tgagttcggc gtatttgact ggcacgccaa
    20821 cggcacggcg accgatgcga agtaatcatt aatcggcaac tttgggttgc cgccaaattg
    20881 ctaatatcga gtacgttgct tcatgccgga tgcggcgtaa acgccttatc cggcctacaa
    20941 gatccaaaga aatcagtaaa ttgcaacaca cattgtaggc ctgataagcg tagcgcatca
    21001 ggcaatatca cttttgaaat caaacttgac gattaacact tctcccagcc gccctgttgt
    21061 gccgtaaacc ccagcgcctg cataaacgcc gtcatcacac cgcgatcttc cacgcctgca
    21121 tccgccatcc accagcatga aacgccagga ttgttacgca aaacctcttc cagcagatat
    21181 tgccccacac cgcgacggcg ggtgacttcc cgcacgcgca gggaatccag tgctccctcg
    21241 gtgccgctta aggttacccg cacggcagcg agcaggcgct cgttaaaacg cgcggcgtag
    21301 atacggtggt tatcgtcaac ctgtaacgag gaaggggaat actccggcca gatcttttgc
    21361 aggtcaatcc ggtcttggtc gctaaatttt tctaatcgaa tgatggtcag cttcatgggt
    21421 aacccgtgta aatcacaaaa gtggaaccag tgtagcgaaa taatttaatc ggaggctttc
    21481 tcttttttat ttcttttggc aggtgattaa ttttttaaca gcaataatta caaaattaaa
    21541 acattagaga atgaaaaatg tccagcataa tcccctgaat gatagtgaat tattccgccc
    21601 tttgtgccgt tattttatgc tgacaaaggc acttttttct gtttatctat caataaattc
    21661 agaatattat ctgttcttaa tcgactgaaa aatagggatt ttaatcgcta ttatcacaaa
    21721 atactgcgct aaccccttaa tcagacaggc aaaaacagtg cagtataaaa aaagaacagt
    21781 ctgatttgtt aacacataaa aacaaagcaa cacaacatca cgaatgggga tttttgacta
    21841 tgaaacggaa tgcgaaaact atcatcgcag ggatgattgc actggcaatt tcacacaccg
    21901 ctatggctga cgatattaaa gtcgccgttg tcggcgcgat gtccggcccg attgcccagt
    21961 ggggcgatat gga
//
LOCUS       DACAOP010000080        21809 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.080, whole genome shotgun sequence.
ACCESSION   DACAOP010000080 DACAOP010000000
VERSION     DACAOP010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21809
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.080"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            197..1711
                     /locus_tag="IT892_003257"
     CDS             197..1711
                     /locus_tag="IT892_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiporter"
                     /protein_id="HAP3136443.1"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD"
     gene            1742..2884
                     /gene="caiA"
                     /locus_tag="IT892_003258"
     CDS             1742..2884
                     /gene="caiA"
                     /locus_tag="IT892_003258"
                     /EC_number="1.3.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="HAP3136444.1"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     gene            3002..4219
                     /gene="caiB"
                     /locus_tag="IT892_003259"
     CDS             3002..4219
                     /gene="caiB"
                     /locus_tag="IT892_003259"
                     /EC_number="2.8.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine CoA-transferase"
                     /protein_id="HAP3136445.1"
                     /translation="MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     gene            4326..5846
                     /gene="caiC"
                     /locus_tag="IT892_003260"
     CDS             4326..5846
                     /gene="caiC"
                     /locus_tag="IT892_003260"
                     /EC_number="6.2.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /protein_id="HAP3136446.1"
                     /translation="MWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFY
                     TLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESTWILQNSQACLL
                     VTSAQFYPMYQQIQQEDASQLRHICLTDMALPADDGVSSFTQLKNQQPATLCYAPPLS
                     TDDTAEILFTSGTTSRSKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQ
                     CTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDRQ
                     HCLREVMFYLNLSEQEKDAFCECFSVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRA
                     GFCYEAEIRDDHNRPLPAGELGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTG
                     DTGYRDEEGFFYFVDRRCNMIKRGGENVSCVELENIIAAHPKIQDIVVVGIKDSIRDE
                     AIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK"
     gene            5955..6740
                     /gene="caiD"
                     /locus_tag="IT892_003261"
     CDS             5955..6740
                     /gene="caiD"
                     /locus_tag="IT892_003261"
                     /EC_number="4.2.1.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA hydratase"
                     /protein_id="HAP3136447.1"
                     /translation="MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
                     PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVN
                     GYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVM
                     TGRRMGAEEALRWGIVNRVVNQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMP
                     VEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR"
     gene            6746..7336
                     /gene="caiE"
                     /locus_tag="IT892_003262"
     CDS             6746..7336
                     /gene="caiE"
                     /locus_tag="IT892_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="HAP3136448.1"
                     /translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVQAGANIQDGCIMHGYCNTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFIKAGFRGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
                     DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR"
     gene            complement(7455..7850)
                     /gene="caiF"
                     /locus_tag="IT892_003263"
     CDS             complement(7455..7850)
                     /gene="caiF"
                     /locus_tag="IT892_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414576.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine metabolism transcriptional regulator
                     CaiF"
                     /protein_id="HAP3136449.1"
                     /translation="MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSREKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     gene            complement(8111..11329)
                     /gene="carB"
                     /locus_tag="IT892_003264"
     CDS             complement(8111..11329)
                     /gene="carB"
                     /locus_tag="IT892_003264"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAP3136450.1"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHSMEEALAVAA
                     EVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNADFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECESNPSDRDKIMVLGG
                     GPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLED
                     VLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVD
                     RLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTA
                     VSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAY
                     TLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKAT
                     GVPLAKVAARVMAGKTLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTG
                     EVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDA
                     THGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRR
                     SALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     gene            complement(11347..12495)
                     /gene="carA"
                     /locus_tag="IT892_003265"
     CDS             complement(11347..12495)
                     /gene="carA"
                     /locus_tag="IT892_003265"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAP3136451.1"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEPYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTIKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIALIEQYRKTAK"
     gene            complement(12951..13772)
                     /gene="dapB"
                     /locus_tag="IT892_003266"
     CDS             complement(12951..13772)
                     /gene="dapB"
                     /locus_tag="IT892_003266"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAP3136452.1"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGSIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL"
     gene            complement(13939..14853)
                     /gene="rihC"
                     /locus_tag="IT892_003267"
     CDS             complement(13939..14853)
                     /gene="rihC"
                     /locus_tag="IT892_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase RihC"
                     /protein_id="HAP3136453.1"
                     /translation="MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEK
                     TTRNALQLLHFWNAEIPLAQGAAVPLVRAPRNAASVHGESGMAGYDFVEHNRSPLDKP
                     AFLAIRDALLRAPEPVTLVAIGPLTNIALLLSQCPECKPHIRRLVIMGGSAGRGNCTP
                     NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALF
                     SHYRSGSMQSGLRMHDLCAIAWLVRPDLFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
                     KPANVKVALDLNVKGFQQWVAEVLALVP"
     gene            complement(14919..15869)
                     /gene="ispH"
                     /locus_tag="IT892_003268"
                     /gene_synonym="lytB"
     CDS             complement(14919..15869)
                     /gene="ispH"
                     /locus_tag="IT892_003268"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HAP3136454.1"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD"
     gene            complement(15871..16320)
                     /gene="fkpB"
                     /locus_tag="IT892_003269"
     CDS             complement(15871..16320)
                     /gene="fkpB"
                     /locus_tag="IT892_003269"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HAP3136455.1"
                     /translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     gene            complement(16428..16922)
                     /gene="lspA"
                     /locus_tag="IT892_003270"
     CDS             complement(16428..16922)
                     /gene="lspA"
                     /locus_tag="IT892_003270"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein signal peptidase"
                     /protein_id="HAP3136456.1"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
                     AKKQ"
     gene            complement(16922..19738)
                     /gene="ileS"
                     /locus_tag="IT892_003271"
     CDS             complement(16922..19738)
                     /gene="ileS"
                     /locus_tag="IT892_003271"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAP3136457.1"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVD
                     QDALKAKFGVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRQMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
                     AEHAEICDRCVSNVAGDGEKRKFA"
     gene            complement(19781..20722)
                     /gene="ribF"
                     /locus_tag="IT892_003272"
     CDS             complement(19781..20722)
                     /gene="ribF"
                     /locus_tag="IT892_003272"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HAP3136458.1"
                     /translation="MKLIRGIHNLSQAPQEGYVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKLLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     gene            complement(20730..20948)
                     /locus_tag="IT892_003273"
     CDS             complement(20730..20948)
                     /locus_tag="IT892_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2575 domain-containing protein"
                     /protein_id="HAP3136459.1"
                     /translation="MCRHSLRSDGAGFYQLAGCEYSFSAIKIAAGGQFLPVICAMAMK
                     SHFFLISVLNRRLTLTAVQGILGRFSLF"
     gene            21051..21314
                     /gene="rpsT"
                     /locus_tag="IT892_003274"
     CDS             21051..21314
                     /gene="rpsT"
                     /locus_tag="IT892_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAP3136460.1"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
BASE COUNT         5211 a         5812 c         5613 g         5173 t
ORIGIN      
        1 aaattaacga aaaaacgccc tctattcacc cgaaacaaaa atgtgatacc aatcacagaa
       61 tacagcttat tgaataccca ttatgagtta gccattaacg cgtccacgag gttaatgata
      121 attatattaa atgttaacaa aaataaaaca aacgggaacg caaaataaat attcgttttc
      181 acagtggaat taactcatga agaatgaaaa gagaaaaacg ggaatagaac cgaaggtttt
      241 ctttccgccg ttaataatcg tcggcatact ttgttggctt acagtcagag atctggatgc
      301 agcgaatgtc gttattaatg ctgtattcag ttacgtcacc aatgtatggg gatgggcatt
      361 tgaatggtat atggtggtga tgcttttcgg ttggttctgg ctggtgtttg gcccgtatgc
      421 caaaaagcgt ttaggtaacg aaccgccaga atttagcacc gccagttgga tctttatgat
      481 gttcgcctcc tgtacgtctg ctgccgtact gttctgggga tcgattgaga tctactacta
      541 catctccacc ccgccgtttg gcttagaacc gaactcgaca ggggcgaaag agttggggct
      601 ggcttacagc ttgttccact ggggacctct gccgtgggcc acttacagct tcctttcagt
      661 cgccttcgct tacttcttct ttgtccgcaa aatggaagtg attcgcccca gctcgacact
      721 ggtgccgctg gtaggtgaaa aacacgccaa agggttgttc ggcactatcg tcgacaactt
      781 ctatctcgtc gccttgatct tcgcgatggg taccagtctg ggccttgcca cgccgctggt
      841 gaccgagtgt atgcaatggt tgtttggcat tccgcatacc ctgcaactgg acgctatcat
      901 cattacctgc tggattatcc tcaacgccat ttgcgtcgct tgcggtctgc aaaaaggggt
      961 acgtatcgcc agtgacgtgc gtagttacct gagcttcctg atgctgggtt gggtgttcat
     1021 tgtcagcggt gccagcttca tcatgaacta cttcaccgat tcggtgggga tgttgctgat
     1081 gtatctgccg cgcatgttgt tctataccga tcccatcgct aaaggcggct tcccgcaggg
     1141 ctggaccgtg ttctactggg catggtgggt gatttatgct atccagatga gtatcttcct
     1201 cgcccgcatc tcccgtggtc gtactgtgcg tgaactgtgc ttcggcatgg tgctggggct
     1261 gacagcgtca acctggatcc tgtggactgt actcggtagt aacactctgc tgttgataga
     1321 taaaaacatc atcaacattc caaatctgat cgaacagtac ggtgtggcgc gcgccatcat
     1381 tgaaacctgg gccgctctgc cactcagcac cgccaccatg tggggcttct tcatcctctg
     1441 ctttattgcc accgttacgc tggttaacgc ctgctcttat accctggcga tgtccacttg
     1501 ccgcgaagta cgcgatggtg aagaaccacc gctgctggtg cgtatcggct ggtcaattct
     1561 ggttggcatt atcggtattg ttctgctggc gctcggcggc ctgaaaccga ttcaaaccgc
     1621 cattatcgcc ggaggatgcc cgctgttctt cgtcaacatt atggtgacgc tctcctttat
     1681 taaagacgcg aaacagaact ggaaagatta attaaccccc aaaatatcaa gaggttgaaa
     1741 gatggatttt aatttaaatg atgagcagga actgtttgtc gccggtatcc gcgaactgat
     1801 ggccagcgaa aactgggagg cctattttgc cgagtgcgac cgtgacagcg tctacccgga
     1861 acgttttgtc aaagcactgg cggatatggg tatcgacagt ctgctgatcc ctgaagagca
     1921 cggtggtctg gacgcggggt ttgttactct cgccgccgtg tggatggagc tgggacgtct
     1981 gggggcacca acctatgtac tgtaccagtt gccgggcggg ttcaatacct tcctgcgcga
     2041 aggcacacaa gagcagatcg acaagattat ggctttccgc ggcaccggta agcagatgtg
     2101 gaactcagcg attaccgaac cgggcgcggg ctccgacgtg ggtagcctga aaacgactta
     2161 tacccgtaga aatggtaaga tttatcttaa tggtagtaag tgttttatta ccagtagcgc
     2221 ctacaccccg tacatcgtgg tgatggcgcg cgacggggct tctccggaca aacctgtcta
     2281 caccgaatgg tttgttgata tgagcaaacc gggcatcaaa gtgaccaaac ttgagaagct
     2341 cggtctgcgt atggatagct gctgtgaaat cacctttgac gatgtggaac tggacgagaa
     2401 agacatgttc ggtcgggaag gtaacggctt taaccgcgtc aaagaagagt tcgaccatga
     2461 acgtttcctg gtagccctga ccaactacgg tacggcgatg tgcgcctttg aagatgcggc
     2521 gcgctacgcc aaccagcgcg tgcagtttgg cgaggctatt ggtcgtttcc agttgattca
     2581 ggaaaaattc gcccacatgg cgatcaaatt aaactccatg aaaaacatgc tgtatgaagc
     2641 agcgtggaaa gcagacaacg gcaccatcac ctctggcgat gcagcgatgt gcaaatactt
     2701 ctgcgccaat gcagcatttg aagtggtgga tagcgcaatg caggtgctgg gcggtgtcgg
     2761 gattgcgggc aaccaccgca tcagccgctt ctggcgtgat ctgcgtgtag accgcgtctc
     2821 cgggggatct gacgaaatgc agatcctgac gctgggtcgc gcggtgctga agcaataccg
     2881 ctaagtccgt gcgctgcctg atgcgacgct gacgcgtctt atcaggccta cggtcggccg
     2941 gataaggcgt ttacgccgca tccggcagtc atgcgctaca taaatttttc aggagctaat
     3001 aatggatcat ctacccatgc cgaaattcgg gccgctggcc ggattgcgcg ttgtcttctc
     3061 cggtatcgaa atcgccgggc cgttcgccgg gcaaatgttc gcagaatggg gcgcggaagt
     3121 tatttggatc gagaacgtcg cctgggccga caccattcgc gttcaaccta actacccgca
     3181 gctctcccgc cgcaatttgc acgcgctgtc gttaaatatc ttcaaagatg aaggccgcga
     3241 agcgtttctg aaattaatgg aaaccaccga tatcttcatc gaagccagta aaggtccggc
     3301 atttgcccgt cgtggcatta ccgatgaagt cctgtggcag cacaacccga aactggttat
     3361 cgctcacctg tccggttttg gtcagtacgg caccgaggag tacaccaatc ttccggccta
     3421 taacaccatc gcccaggcct tcagtggtta cctgattcag aacggtgatg ttgaccagcc
     3481 aatgcctgcc ttcccgtata ccgccgatta cttttctggc ctgaccgcca ccacggcggc
     3541 gctggcagca ctgcataaag tgcgtgaaac cggtaaaggc gaaagtatcg acatcgccat
     3601 gtatgaagtg atgctgcgta tgggccagta cttcatgatg gattacttca acggcggcga
     3661 aatgtgcccg cgcatgacca aaggtaaaga tccctactac gccggttgcg gtctgtataa
     3721 atgcgccgac ggctacatcg tgatggaact ggtgggcatt acccaaattg aagagtgctt
     3781 taaagatatt ggcctcgcac atctactcgg tacgccggaa atcccggaag gcactcagct
     3841 tatccaccgt atcgaatgcc cttacggacc actggttgaa gagaaactcg atgcctggct
     3901 ggcggcacat accatcgcag aagttaaaga acgctttgcc gaactgaata tcgcctgtgc
     3961 caaagtactt accgtaccgg aactggaaag caatccacag tatgtggctc gcgaatcaat
     4021 cactcagtgg caaacgatgg atggtcgcac ctgcaaaggg ccgaatatca tgccgaaatt
     4081 caaaaataac cctggacaaa tctggcgcgg aatgccctca catggcatgg acacggctgc
     4141 cattttgaaa aatatcggct acagcgaaaa cgacattcag gagttggtca gcaaaggtct
     4201 ggccaaagtt gaggactaaa cgcgtggcgt cagtcagctt gcctgactag cgcccgctca
     4261 ataacaaacg aacaacaatg gatagaggtg caatggatat cattggcgga caacatctac
     4321 gttaaatgtg ggacgatctg gcggacgttt acggtcataa aacggcgcta atttgtgaat
     4381 ccagcggcgg agtcgttaac cggtatagtt atcttgagtt aaatcaggag attaaccgca
     4441 cggcaaacct gttttatacg ctggggattc gcaaaggcga caaggttgct ctacatctcg
     4501 acaactgccc ggaatttatc ttttgctggt tcgggttggc aaaaattggc gcgattatgg
     4561 tgccgattaa cgcccgcctg ttgcgcgaag aaagcacgtg gatcctgcaa aatagccagg
     4621 cgtgcctgct ggtgaccagt gcgcaatttt atcctatgta tcaacagatt cagcaggaag
     4681 atgcctctca gttgcggcac atttgcctga cagatatggc acttcccgct gatgatggcg
     4741 tgagttcgtt tactcaactg aaaaatcaac aacctgccac cttgtgctat gcaccgccgc
     4801 tatcgactga cgatacggcg gaaattctct tcacctccgg cactacctcc cgatcgaaag
     4861 gggtggtgat tacccattac aacctgcgct tcgctggata ttactccgcc tggcagtgtg
     4921 cactgcgtga cgatgacgtc tacctgacgg taatgcctgc gtttcatatt gactgccagt
     4981 gtactgcggc gatggcggcg ttttctgccg gggccacctt tgtgctggtc gagaaataca
     5041 gcgcccgcgc cttctgggga caggtgcaga agtaccgcgc caccattacc gaatgtattc
     5101 cgatgatgat tcgtacgttg atggtgcagc cgccttcagc gaacgatcgg caacactgcc
     5161 tgcgggaagt gatgttttat ctcaacctgt cggagcagga aaaagacgcg ttttgtgaat
     5221 gcttcagcgt tcgcttgctg acgtcatatg ggatgacgga aaccattgtg ggcattatcg
     5281 gcgatcgccc tggcgataaa cggcgctggc cgtcgattgg tcgggcgggc ttttgctacg
     5341 aagcggagat ccgcgacgat cacaatcgtc ccctcccggc tggtgagctc ggtgaaatct
     5401 gtattaaagg cgtaccaggg aaaaccatct tcaaagagta ttttctcaac ccgaaagcca
     5461 ctgcgaaagt gctggaagcc gatggctggc tacataccgg cgataccgga taccgcgacg
     5521 aagagggctt tttttatttc gtcgatcgcc gctgcaatat gatcaaacgc ggtggcgaga
     5581 atgtctcctg cgtggagctg gaaaatatta tcgccgcgca cccgaaaatt caggacatcg
     5641 tggttgtggg tattaaagat tcgattcgcg atgaagccat caaagcattt gtggtgctga
     5701 atgaaggtga aacattgagc gaagaggaat ttttccgctt ctgcgaacaa aatatggcga
     5761 aatttaaagt gccctcttat ctggagatca gaaaagatct gccacgtaat tgctcgggga
     5821 aaataattag aaagaatctg aaataaatga aacggcaggg aactacccta ccagctaata
     5881 atcacactct aaaacaatat gcattttttg cagggatgtt gtcgtccctg aaaaagcaaa
     5941 aatggagaaa aggaatgagt gaatcattac atctgacccg caatggatca attctggaaa
     6001 ttacccttga tcgtccaaaa gcgaatgcta ttgatgcaaa aaccagcttt gaaatgggcg
     6061 aagtatttct aaatttccgt gacgatccgc aattacgtgt cgccattatt accggtgccg
     6121 gagagaagtt cttttccgcg ggctgggatt taaaagcggc agcagaaggc gaagcaccgg
     6181 atgctgactt tggcccgggt ggatttgcgg gattaaccga aattttcaat ctcgacaaac
     6241 cggttatcgc agctgtgaac ggctatgcct ttggcggcgg ctttgaactg gcgctggcgg
     6301 cagattttat tgtttgtgcc gataatgcca gcttcgccct gccggaagcc aaactgggca
     6361 tcgttcctga cagcggcggc gtgctgcgtc tgccgaagat cctgccgcct gccatcgtca
     6421 atgaaatggt gatgaccggc agacgaatgg gcgcagaaga ggcgctgcgt tgggggatag
     6481 tcaaccgcgt ggttaaccag gcggaactga tggataacgc ccgcgaactg gcgcagcagc
     6541 tggttaacag cgccccgctg gcgattgcgg cgctgaaaga gatctaccgc accaccagcg
     6601 aaatgccggt ggaagaagcg tatcgctata ttcgcagcgg cgtgttgaaa cactatccgt
     6661 cggttctgca ttcggaagat gccattgaag ggccgctggc gtttgccgag aagcgcgatc
     6721 cggtgtggaa aggacgttaa caaccgtgag ctattacgcc tttgaggggt taattccggt
     6781 ggttcacccg acggcgtttg tccatcccag tgccgtcttg attggcgatg tgattgtggg
     6841 agccggtgtc tacatcggcc cactcgcctc actgcgtggt gactacgggc ggttgatcgt
     6901 gcaagcggga gccaatattc aggatggctg cattatgcat ggctactgca acactgacac
     6961 catcgttggg gaaaacggtc atatcgggca cggagcgatc ctgcatggtt gtgtgattgg
     7021 tcgcgatgca ctggtcggga tgaacagcgt gattatggat ggcgcggtca ttggcgaaga
     7081 gagcattgtt gccgctatga gctttatcaa agcgggcttt cgcggcgaga aacgccagtt
     7141 gttgatgggt acgccagccc gcgctgtacg cagcgtgagt gacgacgagt tacactggaa
     7201 acggttgaat accaaagagt atcaggatct tgtcgggcgc tgtcatgcat cgttgcatga
     7261 aacgcagcca ctgaggcaaa tggaggaaaa tcgcccccgt ttgcagggga cgacggatgt
     7321 gacgccgaaa cggtgatctt tccggatgcg gcgtaaacgc cttatccgac ctggctggaa
     7381 aggaaccgta ggccgtataa gatgcgccag catcgcatcc ggcgaccagg tcgcacggta
     7441 tcaacgaaac gacattaacg acgcatactc tttgacaaca tcatctgcca cttctgctcg
     7501 cggttaagtt ccgtgagcgg aacggcagga atacgcggcg tctttcttac gccgactaat
     7561 ttttcccgac tgttattgcg caggcgcgcg taaatttgct catcgatatc gaccacttta
     7621 accagtcgct gacactggca tccccgccct tccagcttat tagggatcat cttaacttcg
     7681 cagcttattt ctgtgacttc cgacagaata taagtcaggg tattaaccgc cttgctgtgt
     7741 tcaatatcga aatgaataga gatctctctt gctatcaccc accgattttc agccatcatc
     7801 cattcggcga ttaacaagta gagtggtttt tcaacatatc cttcacacat acgaactcca
     7861 gtttcacaaa ttaaaagtct ggctatgact cgttttgaag caattaaaca aggccatatt
     7921 aaaattgtgg atatatcgat agtatgcaac ttcaccgtcg ataagtgtga gctaaatcct
     7981 gcttatgtca tcaaaaatat cgattcccca aaagatttac ttaatgggca aaaaaaacgg
     8041 tcctcatcag agaaccgtat tagttattcg atcaaattag cggatgaaaa atatccgcca
     8101 tgacacgcta ttatttgatc tgcgcgtgca tttcctgcac cgaaattact ttttcggtcg
     8161 catcagcatt cagcgccatc gcagtagcga aaccaccgtt cagggtggtg tcataatgca
     8221 ctttatattg cagcgcactg cgacgaatca cgcgggagtc ttcaatcgcg cgacgacctg
     8281 aggtggtgtt gatgatgtag gtatattcgc cattcttgat gcggtcctga atgtgcggac
     8341 ggccttcatg caccttgttt accagacgcg gattgatacc cgcttcgccc agcacaatcg
     8401 ccgtgccgtg ggtcgcatcc agctcgaagc cctgtttcag cagttttgcc gccaggtcca
     8461 ccacgcgttc tttgtcgcct tcgcgcacgg aaagcagcgc acgaccgtgt ttcttcatgg
     8521 tggagttgct gcccagctgc gctttggcga acgcttcagc gaaggtgcgg cccacgccca
     8581 tgacttcccc ggtagagcgc atttctggcc ctaacagcgg gtcaacgccg gggaatttat
     8641 tgaacggcag caccacttct ttcaccgagt agtacggagg gataacttct ttggttacgc
     8701 cctgctcggc cagcgttttg cctgccatca cgcgcgccgc cactttcgcc agcggtacgc
     8761 cggtggcttt ggagacgaac ggaacggtac gcgccgcacg cgggttaact tcaatcaggt
     8821 agacttcgtt gtttttaacc gcaaactgca cgttcatcag gccgcgcacc tgcaattcga
     8881 aggccagttt ctgcacctgc tggcgcatca catcctgaat ttcctgactt aaggtgtagg
     8941 ctggcagaga acatgcggag tcaccggagt gcacgcccgc ctgctcgatg tgctccatga
     9001 tgccgccaat cagcaccatt tcgccgtcgc agatggcatc cacgtcaact tctactgcgt
     9061 catcaaggaa atgatccagc aacactggcg catcgttaga cacgctaacc gccgtctgga
     9121 agtagcgacg caggtcagct tcgtcataga cgatttccat cgcccgaccg ccgagaacgt
     9181 aagacggacg taccaccagc gggtagccaa tctctttcgc cttctctacc gccatttcaa
     9241 tagcggtaac ggtggcgttc gccggttgtt tcagtttcag acggtcaact gcatgctgga
     9301 agcgttcacg gtcttccgca cggtcgatag catccgggct ggtgccgata accggtacgc
     9361 cagcggcttc cagtgcgcgc gccagtttca gcggggtctg gccgccgtac tgaacgataa
     9421 cacctttcgg cttctcaata cgcacgattt ccagcacatc ttccagagtt accggctcga
     9481 agtagaggcg atcggaagtg tcgtagtcag tggagacggt ttccgggtta cagttaacca
     9541 taatggtttc gtaaccgtct tcgcgcagcg ccagtgaggc gtgtacgcaa cagtagtcga
     9601 attcgatacc ctgaccgata cggttcgggc cgccgccgag gaccatgatt ttgtcacggt
     9661 cagatgggtt ggattcgcac tcttcttcat aagtggagta catataagcg gtgtcggtag
     9721 caaactctgc cgcacaggta tccacgcgct tgtaaaccgg gtgcaggtca tactggtcac
     9781 gcagcttacg gatttctgct tcacgcacgc ccgcgagttt tgccagacgc gcatcggcaa
     9841 agcctttgcg tttcagctgg cgcaggaagt cagcgttcag gccagtgatg cccacttccg
     9901 ctactttctc ttccagacgc accagttctt caatttgtac caggaaccag cggtcaatgt
     9961 tggtcaggtt aaagacgcca tctacagaca ggcccgcacg gaaagcatcg gcgatgtacc
    10021 agatacgctc tgcgcctgca tctttcagtt cgcggcggat tttagtcagc gcttccgggt
    10081 cgtcgagact gactttcggg tcgaagccag ttgcgcccac ttccaggccg cgcagcgctt
    10141 tttgcaggga ttcctgctgc gtgcgaccaa tcgccatcac ttcgccaacc gatttcatct
    10201 gagtggtcag acggtcgtta gcaccggcga atttctcgaa gttgaagcga ggaattttag
    10261 tcaccacgta gtcgatggac ggctcgaagg aggccggagt acggccaccg gtgatgtcgt
    10321 tcatcagctc gtcgagggtg taacccaccg ccagtttcgc cgccactttg gcaatcggga
    10381 aaccagtggc tttcgacgcc agcgcagagg agcgagacac gcgtgggttc atttcgataa
    10441 caatcaggcg accgtttttc gggttcaccg caaattggac gttggaacca ccggtttcaa
    10501 cgccgatttc acgcagtacc gccatcgagg cgttacgcat gatttgatat tctttgtcgg
    10561 tcagcgtttg ggctggcgcg acagtgatgg agtcaccggt gtggatgccc atcgcatcaa
    10621 agttttcgat agagcagacg atgatgcagt tgtcgttttt atcacgcacc acttccatct
    10681 cgtactcttt ccagccgatc agcgactcat caatcagcag ctctttagtc ggagagagat
    10741 ccagaccgcg ggcgcaaatt tcttcaaact cttcgcggtt ataagcgata ccgccgccgc
    10801 taccacccat ggtaaaggat gggcgaataa tgcacgggaa gccaacttca gcggcaaccg
    10861 ccagcgcttc ttccattgaa tgagcgatac cggaacgcgc agtttccaga ccgattttct
    10921 tcatcgctac gtcgaaacgg cggcggtctt cggctttatc aatcgcatcg gcagtggcac
    10981 caatcatggt gacgccgaac tcttccagca cgccctgacg ctcaagctcc agcgcacagt
    11041 tcagcgccgt ctgccccccc atggttggca gcaccgcgtc cgggcgctct ttttcaataa
    11101 tcttgcgtac cacttcccag tgaatcggct cgatgtaggt tgcatcagcc atttccgggt
    11161 cggtcatgat agtcgccggg ttggagttca ccagaatgac gcggtaaccc tcttcacgca
    11221 gggctttaca cgcttgcgcg ccagagtagt caaactcaca cgcctgaccg ataacaatcg
    11281 ggcccgcacc cagaatcagg atacttttta tatctgtacg ttttggcatg gctcttttac
    11341 tcctgattac ttagcggttt tacggtactg ctcaattaac gcgataaagt ggtcgaacaa
    11401 cggcgcggcg tcgtgtggac cagggctggc ttccgggtga ccctggaagc tgaacgccgg
    11461 tttatcggtg cgatgaatgc cctgtaacgt accgtcgaac agggatttat gcgtgacacg
    11521 caggtttgca ggtaatgttg cttcgtccac cgcaaaaccg tggttctggg cggtgatcat
    11581 caccacgttt ttctcaacat ctttaaccgg atggttgccg ccgtggtgac caaatttcat
    11641 tttgatggtc ttcgcaccgc tcgccagcgc cagcagctga tgaccgagac agatgccgaa
    11701 taccggaata tcggtttcga ggaatttctg gatggctgta atggcgtaat cgcacggggc
    11761 cgggtcgcca ggaccgttgg agaggaagat gccgtccgga ttcattttca gcacatcttc
    11821 cgcagaagtt tgtgccggaa cgatggtcag tcgacaacct ctatccacca gcatacgcag
    11881 gatgttgcgc ttggcaccaa aatcataagc cacgacgtgg aacggcagct cgtcttcttt
    11941 tttcgcttct ggcaggccgc cggtcagtgt ccagctccct tgtgtccagc tatagggttc
    12001 tgcggtggtt acttcttttg ccagatccat gccgttcaga cctgggaacg cacgggcttt
    12061 ttctaacgcc agcgccgcat ccgggttgtc acccgcaata atgcagccat tctgagcacc
    12121 tttctcacgc agtaaacgcg tcagcttacg ggtatcgata tcggcaatcg ccactatgtt
    12181 atggcgcttc aggtaagaag agaggtcttc ggtattacgg aagttgctgg caatcagcgg
    12241 caggtcgcga atcaccagac cttgggcatg tacctgagaa gattcttcat cggcgtcatt
    12301 agtgccgaca ttgccaatat ggggataagt aagagtaacg atttgacgag aataggaagg
    12361 atcagtgagg atttcttgat aaccggtcat tgaagtattg aaaacgactt ccccaaccgc
    12421 cgaacctgtt gcccctatgg cccgaccgtg aaactgggtt ccgtcttcca gaaccaatag
    12481 cgctgactta atcaaaacac cctccagaga atattcactc actttatttg catattaatt
    12541 cacaatgatg acgtaaatca atgcaaatct gcttaccgac gaatttctgg caaacggcgg
    12601 cattctggag atatgggcgc taaaagtcaa cttaatggcg ggatttttta tattattttg
    12661 tggctcatgc atgttttaca ggcattaagc gacaaaaaga tcatataaca tgttctggaa
    12721 aacgcttgcg cagcaagaag attgcatgaa ataaaaatga gcagaaaaaa gtggaccaga
    12781 tggtcaaaat ttacattaaa acaacaaaaa cagaatacaa aatatgtaat tttcagcatt
    12841 tgcattaaat ttaaaatcat aacaccaaaa ataaaagggc caaaaattaa agccctttat
    12901 aatcaataaa ttgaatgtgt tatttttgca tcatcataaa cattttgtgg ttacaaatta
    12961 ttgagatcaa gcacatctcg catatcaaaa agaccacttt ccttaccact caaccacaaa
    13021 gccgatctta ccgcgccgtt agcaaatgtc atgcggctgg acgccttatg ggtgatctcc
    13081 agacgctcgc caatatcggc aaacatcgcg gtatgttcgc caacgatgtc acctgcacgc
    13141 acggtggcaa aaccaatgct accaggcaca cgttcaccgg tatggccttc acgactgtag
    13201 accgcgcaat ctttcagatc tttatcaagg gcgtgggcga tcgcctctcc cattgccagt
    13261 gcggtgcctg acggcgcatc aactttatgt ctatgatgtg cttcaataat ttcgatatcg
    13321 gtgtagtcac ccatcacttt ggctgctttc tccagcagct taagcatgac gttaacgcca
    13381 acgctaaaat tggcggcaaa gacaatcgca atatcggcgg cggcgtcacg aatcgcctgt
    13441 ttaccggctt cgtcaaaccc cgtagtgccg atcaccatcc ctttgccatg ctggcgacaa
    13501 aaagcgagat gattcagcgt accttccgga cgggtaaaat cgataaacac atcaaaatca
    13561 tcttttaccg catcgaggct actttgcacg gtcacgccgg ttttcccggc tccggccagt
    13621 tcgcccgcat cgctgcccag taaagaagat ccttcgcgct ccagcgccgc gcccagctgc
    13681 acgccttcta atgccagcgc cgcctgaatc aactggcggc ccatacggcc cccggctccc
    13741 gcgatggcaa cgcggatgtt tgcatcatgc atagctattc tcttttgtta atttgcatag
    13801 accgttttca gagtaaccag cgcatcgcta cgccgccagc caaaaacgct gataattaga
    13861 aattaatgat aaacagggag ggatatcagt gaaaggcatg agtcgatgaa tgactgcatg
    13921 ccgataacat gtgacaggtt acggcaccag agccagcacc tcagctaccc actgctggaa
    13981 gccttttaca ttcagatcca atgccacctt tacattggct ggtttgccca ggcaaccgtc
    14041 gatatcaacc accgtcgtgc ctgaggtaaa ttcgccttga gtttctaccg cgacaaaaca
    14101 cggcttgagg gtgaataagt ccgggcgcac cagccaggcg atggcgcaga gatcgtgcat
    14161 tcgcagtcca ctttgcatac tgccgctacg gtagtggcta aacagggcgt ggagcatttt
    14221 tccggtgcga ttcaactccg gcaaagtagc gagatagtca ggggttaata ttgcctgatt
    14281 ggtgacatcc agaccgcaca tgacgatttc gatgccgcta cggaagacac aggctgccgc
    14341 ttctggatcg gcagcgatat taaactcggc gtttggtgtg cagttgccgc gaccggcgga
    14401 accgcccatg atcaccagac ggcgaatatg cggtttgcat tccgggcatt gtgaaagtaa
    14461 cagcgcaata ttggttaacg ggccgatggc taccagggta acaggctcag gcgcacgcag
    14521 cagggcatca cgaatcgcca gaaatgcggg tttgtccagt gggcttctgt tgtgctcaac
    14581 aaagtcgtag ccagccattc ccgattcacc gtgcacagat gctgcattac gcggtgcgcg
    14641 taccagcggc acagcggctc cctgggcgag cggaatctcc gcattccaga aatgcagcag
    14701 ttgcagggcg ttgcgggtgg ttttctcaac cgagacatta cccgcgacgg tggtcatcag
    14761 ttgcaggtcg agttcgggtg caaaaatcgc ggcagcaatg gcgacggcat cgtcaatgcc
    14821 ggggtctgta tcgaggaaga taggtaaacg catgttttct ccataaaaaa tgccggtaac
    14881 aagaccggca ttttcgcata acttaggctg ctaatgactt aatcgacttc acgaatatcg
    14941 acacgcagct ctttcggcac ttcgaaaaca atattttctt cacggccttc cagcggaatg
    15001 gcttcaccac cgcccagctg ttgcaaacgt gccaccacat tctgcaccag aatatccgga
    15061 gccgatgcgc ccgcagtcac gccgacgcat ttaacctctt tcacccactc ttcctggata
    15121 tctttcgcat cgtcaatcaa aaacgcgcgt ttgcccatac gttgggccag ctccgccaga
    15181 cggttggagt tggaggagtt tttcgaaccg accaccagca caacttccgc ctgttctgcc
    15241 agggcgcgta ccgcttcctg acggttagtc gtggcgtagc agatgtcatc tttgcgcgga
    15301 ccgacaattt tcgggaagcg tttacgcagc gcgtcgatca catcagacgt gtcatccacc
    15361 gacagcgtgg tttgggtcat aaaggagagc ttctcttcgt ttttgaccgt cagtttccac
    15421 acatcgtctg gcgattcgac cagatacatt cccccttccg ggttgctgta ctgacccatc
    15481 gtcccttcca cttccgggtg cccggcgtga ccgataagaa tagattcttc gccacgacgg
    15541 ctggcgcggg cgacttccat atgcactttg gtcaccagcg gacaggtggc gtcgaatacc
    15601 gtcaaatcgc ggctttttgc ttcgttacgt accgcctgag aaacaccgtg tgcggagaaa
    15661 atcaggatcg cgccgtccgg tacttcgcta atctgctcaa taaagatagc cccacgctcg
    15721 cgcaggctat cgaccacgta gcggttatgc accacttcgt gacggacata tatcggtgcg
    15781 ccgtaaatgg ccagcgcgtt ttcaacaatg ctgatagcgc ggtctacccc ggcacaaaaa
    15841 ccacgtgggt tggccaacag gatctgcatg ttacgcctcc agtgccggat cgatttccag
    15901 cacttcaata tcaaaatgaa cggtctgccc ggccagcgga tggttgaaat caacggtaat
    15961 ggagtcgccg ttaatttcgc ggatcacgcc aggcatctca ctgccatcca ttgcggtaaa
    16021 aagcatgatt gcgccaattt ctggctcgcc tgcatccata aactcacggc gggagaagta
    16081 ctgaatcagg tccggtgacg gcacgccaaa cgccgcatct ggctccagcg agaaagtggt
    16141 tttatcgccc actttcagcc ccagcaggtg ttgctccagc ccttcggaaa gagaagcatc
    16201 gcccaggcgg aacagcgccg gtttaccgtt gttgcgggta gactcggcgg tggtgccatc
    16261 gtcgagtttt agcgtgaaat gcaccaggac ggcgctattg ctctgtacag attcagacat
    16321 gcaggtttgc tcttatattt tgaggatttt tgccggatgc ggcctacgat ttcgcagcaa
    16381 tctgtaggcc ggataagatg cgtcagcatc gcatccggca gggtttatta ttgttttttc
    16441 gctttagaag gtaaaaaacc ttccagcaca atcagtgccg caccgacaca aatggcagta
    16501 tcggcaaggt tgaaggtggc gaagtgccag tcgccgacgt agaagtcgat catatcgaca
    16561 acgaagccgt gccacaggcg gtcgaacagg ttgcccagcg cgccgccaat aatcagcgcg
    16621 taagcgatat tgtttagctt ctgcgtggcc ttcgagcgat acatcatcac tgccaggatc
    16681 acgctaatac caatcgcaat accggcaaag aaccaacgct gccagccgcc gctatcggca
    16741 aggaaactaa acgccgcgcc atagttacgc gcataatgca gattaagcga cgggaacagc
    16801 gggaccgtat cccccagagc aaagttctgg aggatcaggt atttgctgcc cagatcgata
    16861 atcagcacga ctaccaccag ccacagccag cgtagccctg ttgaacagat cgattgactc
    16921 atcaggcaaa cttacgtttt tcaccgtcac cggcgacgtt gctgacacag cggtcgcaga
    16981 tttctgcgtg ttccgccacc ttgccgacat cctgggtgta gtgccagcag cgtgggcact
    17041 tctcaccttc ggctttactc aacgcgactt tcaggccttt gagtacttcg ctctgctgag
    17101 catcagcagg tgcgtcgtta tagtctgcaa cggtagcgcc ggaggtcaac aggacaaatc
    17161 gtaattcatc gcccagcgcg gtcagtttcg ccgccagttc cggttctgca tacaaggtta
    17221 ctgccgcttc cagcgagcca cccactttct tgtcggcacg cgcttgctca atgactttgt
    17281 tcacttcgcc acgcactttc aacagctcgt cccagaacgc atcgttcatt gcttcactgt
    17341 ctgccagacc aaacaggcct tcgtaccact caccggtgaa gacgtatttt tcacgttcgc
    17401 ccggcaggta gccccacact tcatcagcgg tgaaggagag gattggtgcc atccagcgca
    17461 ccagcgcttc cgcgatgtga tacagcgcag tctggcagct acgacgcgcc acactgtccg
    17521 ctttggcggt gtactgacgg tctttgatga tgtcgaggta gaaggaaccc atctcaacgg
    17581 agcagaagcg catctgacgc tgtaccacct cgtggaaatc gtatgcttcg tacgccttga
    17641 ggatgtcttc ctgcgccgct ttcgcacaac ctacggccca gcgatccagt accaccatct
    17701 cttccggttt caccatatct tttgccggat caaaaccgtt caggtttgcc agcaggaagc
    17761 gcgcggtgtt acggatacga cgatagctgt cggcagcacg cttcaggatc tcgtcagaaa
    17821 cagccatttc gccggtgtag tcggttgatg ccacccacag acgcagaata tccgcgccca
    17881 gtttgttcat cacatcctgc ggcgaaacgg tgttgccgat ggatttagac atcttgcggc
    17941 cctgaccatc cacggtaaag ccgtgggtca gtacctgacg atacggtgct ttgcccttca
    18001 tcgcggtaga gatcatcaga gaggacatga accagccacg gtgctggtct gaaccttcca
    18061 gatacatgtc cgcagcgtga ccggcaaatt ccggacgcac gtcaacaacg gaagagtggg
    18121 tagatccgga gtcaaaccat acgtcgagag tatccggcac tttcacgtac tgatcagctt
    18181 catcgccgag gatctctttc gcatcgagat cccaccacgc ctggatgccg tcaacttcaa
    18241 cgcgtttagc cacttcttcc atcagttcga gggtacgcgg atgcagctct tccgtgtctt
    18301 tatgcacgaa cagtgacatc ggtacgcccc aggtgcgctg acgggagata caccagtcag
    18361 gacggttagc aaccatcgac tcgatacgcg cctggcccca gtccgggatc cactgcacgc
    18421 ctttgatctc tttcagtgac tgcgcacgca gacctttctg atccatgctg acgaaccact
    18481 gcggcgtcgc gcggaagatg atcggcgttt tgtgacgcca gcagcacgga tagctgtgct
    18541 gcattttctc aacgtgcagc agcgcgcctt tttcctgcag cagcgcaacg acgatgtcgt
    18601 tcgctttgaa gacgttcacg ccatccagcg tcgggtaagt gcccggcaga taagtgccgt
    18661 ccgggccaac cgggttagcg gtttccaggc catatttctg accgatcaca tagtcgtccg
    18721 ggccgtggcc aggcgcggtg tgaacggcac cggtaccggc atccagggta acgtgatcgc
    18781 cgaggatagc aggaacgtcg aagcccataa acggatgggt aaagcgcagc agctcaagct
    18841 ccgcaccttt taccgtgccg agaatggtgt aatcggtcac gccgatacgc tgcattacgc
    18901 tttcaaccag atctttcgcc agaatcacgg cctgaccgtc gatctgcacc agcgcatagt
    18961 cgaaatcagg tgcaatagag attgcgcggt tggcaggcag agtccacggc gtagtggtcc
    19021 agatcaccag cgagattggg ccgttaacgt tgcttacgcc aaattttgct ttcagtgcat
    19081 cctgatcgac cgcctggaaa gcaacgtcga tggacggaga agttttgtcg taatactcaa
    19141 cttccgcttc cgccagcgca gaacggcagt caacgcacca gtgtaccggc ttcgcgcctt
    19201 tgtgcaggtg accgttgccg atgattttgc ccagcgcgcg gatgatatta gcttcagttt
    19261 tgaaatccat ggtcaggtac gggtgggacc agtcgcccag cacgcccaga cggataaagt
    19321 ctttgcgctg accgtcaacc tgggtcgccg cgtattcgcg gcacttggcg cggaactcag
    19381 cggcggtgaa tttctcaccc ggcttaccgt attcttgctc tactttcagc tcgatcggca
    19441 gaccgtggca gtcccagcca ggcacatacg gcgagtcata accggaaagc cctttggact
    19501 tcacgataat gtctttcaga atcttgttaa ccgagtgacc aatatgaatg ctgccattcg
    19561 cataaggagg gccatcatgc agaatgaagg tttttttgcc ttttttagcc gcacggatga
    19621 tgccgtacag atcatcatca gtccaacgcg ccagcattcc cggttcgcgc ttggcgagat
    19681 cgccacgcat cgggaaccct gtttccggca aattcagggt tgatttatag tcactcatca
    19741 gattctcggt tccgtgtttc ggtttgatta cataacaggc ttaagccggt tttgttagcc
    19801 caaaaaattc gcgggcggtt aattcatcac gcgcaatctg cgctttcagt tcgtccagcg
    19861 acgcaaatcg ctgctcattg cgtatttttt tacgcagcac tacttgtata tggcgaccgt
    19921 aaaggtccat tgcaacatct aacaaatgca cttccagctg ctggcgaata ccggcaaccg
    19981 ttgggcgtgt tccgatgttt gccacaccgg gtaacggctt ttcaccgagg cccagcactt
    20041 ctaccgcata aacccctttc accggggaaa cctgacggcg tagcggtaca ttcgccgtcg
    20101 ggaaacctat agtgcgccct aattcatcac cgtggactac acgcccggag atggcaaacg
    20161 ggtgccccag taaactttct gccagagcca gattgtcatc cgccagcgcc tgacgcacag
    20221 cggtgctgct gatacgcacg ccaccttcgc aaaaagtttg cgtactggtg atatcgaagc
    20281 cgtattccat gccagctttc tgtaataaca agaaatcgcc ttcacgacca gcgccaaagc
    20341 ggaaatcatc acctacggca agaaatttta cgcgcaaaag cttcaccaga agatcgctga
    20401 tgaaattttg cgcggttaac gccgcgaaac gcctgtcgaa acgcacgcac agcacgtaat
    20461 caacgccaca ctctgcaagg taacgcagtt tttcccgcag ccgggtcagc cgtgccgggg
    20521 ctttatcggt agcaaacagt tccagtggtt gaggttcaaa aagcatcacc atcaccggta
    20581 agttgcgctt gcgcccttct tcctgcaagc cctgtaacag cgcgcgatga ccgcgatgca
    20641 cgccgtcgaa attaccaata gtcagcacat acccttcttg cggggcctgg ctgagattat
    20701 gtatgccgcg tatcagcttc atgtctggct caaaacagtg aaaatcgtcc gagtatacct
    20761 tgtacagcgg tcaaggttaa ccggcgattg agtaccgaaa tcagaaagaa gtggcttttc
    20821 attgccatgg cgcaaatcac gggaagaaac tgaccgcctg ctgcaatttt tatcgcggaa
    20881 aagctgtatt cacaccccgc aagctggtag aatcctgcgc catcactacg taacgagtgc
    20941 cggcacatta acggcgctta tttgcacaaa tccattgaca aaagaaggct aaaagggcat
    21001 attcctcggc ctttgaattg tccatataga acacatttgg gagttggacc ttggctaata
    21061 tcaaatcagc taagaagcgc gccattcagt ctgaaaaggc tcgtaagcac aacgcaagcc
    21121 gtcgctctat gatgcgtact ttcatcaaga aagtatacgc agctatcgaa gctggcgaca
    21181 aagctgctgc acagaaagca tttaacgaaa tgcaaccgat cgtggaccgt caggctgcta
    21241 aaggtctgat ccacaaaaac aaagctgcac gtcataaggc taacctgact gcacagatca
    21301 acaaactggc ttaatcgcca atttgctgaa gctttgtgaa aaagcccgcg caagcgggtt
    21361 tttttatgcc tgctgctttt gtgatgcgtg agagaacaca ctgccggttg ccagatagtc
    21421 aaaagttgca ggttcttgca gacatgccgt tgtactatct gaactcttcg tggcttaaga
    21481 atcgtagaac catcggctga tacattctga acaagaatat ctactcaatc tccagacccc
    21541 ctacaaagaa tgtggatatt gtgatacaca ttgaggtatt aaacttaaga ccactctatt
    21601 tttgaattaa attcctatat actttaacca ttcataaata tctcctcatt agaccttgta
    21661 aattattaac agcaatcaac acaggttaaa tacctattta tattgtactt cttaaaatta
    21721 atgagcgatt tttgatagta gtcacattca ctcataaatt aaattaataa aaattcatca
    21781 acttcaagga cagataatga caaatggta
//
LOCUS       DACAOP010000081        21545 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.081, whole genome shotgun sequence.
ACCESSION   DACAOP010000081 DACAOP010000000
VERSION     DACAOP010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21545
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.081"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            1..879
                     /locus_tag="IT892_003275"
                     /pseudo
     CDS             1..879
                     /locus_tag="IT892_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610795.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1113..2096
                     /locus_tag="IT892_003276"
     CDS             1113..2096
                     /locus_tag="IT892_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136461.1"
                     /translation="MSITSLGEFKKCLLERLGYLNTQICTSSSVPTLPTVVNRPELAS
                     NYFRIVTVQQLFPKDKHFHPSDVTLDNPEVRWKHREHLAEICKLTEQTLDAKLKTESR
                     DHTSTADLIVFSELAVHPEDEDIVRALAFRTRSIIFCGFVFCEQDGQIVNKARWIIPD
                     SSESGTQWRVRDQGKFHMTSGEMSLGVHGYRPSQHIISIEGHTEGPFKLTGAICYDAT
                     DIKLAADLRDLTDMFVIAAYNKDVDTFDNMASALQWHMYQHVIITNTGEYGGSTMQAP
                     YKEKHHKLISHAHGTGQIAISTADIDLAAFRRKIKEYKKTKTQPAGFKRKH"
     gene            2105..2539
                     /locus_tag="IT892_003277"
     CDS             2105..2539
                     /locus_tag="IT892_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HAP3136462.1"
                     /translation="METLVKLATIASPLVSAGVAIWAILVAKSTISENKEIAKKTIAD
                     TAYQAYLQLAMENPHFSKGYSADCRQERDPMYDQYVWYVARMIFCFEKIIEVEGNLKD
                     SSWTNTLEKHLKFHSEHFKKTKVVEETLYISPILDLIRCATN"
     gene            complement(2836..3936)
                     /locus_tag="IT892_003278"
     CDS             complement(2836..3936)
                     /locus_tag="IT892_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001494628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hsdR"
                     /protein_id="HAP3136463.1"
                     /translation="MFDVDDTAPDTPAPRELSQDVQALINNGLDFLDKAREELEASKP
                     KFSVVSFWTAVEILLKVPLAHEHWSLVCSPKKPIKKQAYLAGDFQSVTYEETRERLKD
                     VLERPLDRETDSAFDKVRKHRNRVVHFYHPTFTEAEQRQILKEQADAWFALNRLLRDE
                     WKVIFGVKHNWKLAFGETRLIRGNKFYAEVRFKQVKPELDQLSEKNIQIGNCNECHQH
                     ATVTGTETTGNENRKLEVTRCKVCTSAVRQITLVCPDCEIPQLLPEGDSDFECEHCDY
                     TSDRYKLLDEELFHSVDEQLLSVFPAGCTNCMTPESVCKFGDGYLCTQCFIYYTELHV
                     CGYCGHLSDSVPELSHIRGCEFCDGDQRYFDD"
     gene            4335..4937
                     /locus_tag="IT892_003279"
     CDS             4335..4937
                     /locus_tag="IT892_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010340155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP3136464.1"
                     /translation="MNTSPWNKDRIIGQKRPLQISHIWGIRIRLELECKTRDLALFNM
                     ALDSKLRGCDLVKLKVSDVAYGSSVSSRATVLQQKTGSPVQFEITKGTREAVSALIKL
                     GNLRSKDYLFRSRVGTNQHISTRQYNRIFHGWVAKLGLEDSLYSTHSLRRTKPYLIYK
                     KTKNLRVIQLLLGHKKLESTVRYLGIEVDDALEISESIEV"
     gene            5242..7554
                     /locus_tag="IT892_003280"
     CDS             5242..7554
                     /locus_tag="IT892_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP3136465.1"
                     /translation="MNDKLKMWRDKAGLSQQEVAERAGENVLSQKQVSRIEQAPLSQN
                     LELVLAYLRIVAPEKIQEFITDCLKTQLNTSSLNQNYTQQKENMMRNKKELIEYLERS
                     IATLSNTSNPFIKNSSITKDIAELKDNLKDIHAKPVLSAMGPSDAGKSTLLNYILGSE
                     ILPAKWQPATCLVTLLMHTQDKPDYLDKNKSVFIFKNGFKPHMIFDRQMLADFLIDSG
                     GKELIKTYGEKDENDNVLNPQAYMVVVFESFAILETIWLLDTPGQLIEPEMYDEIDGC
                     SSEEILNDKAKAMSAISLVDGLIFASATTKFMRDEDPEFLQNILMHKVPLEGDKPLAN
                     LIILKTHSYDQITAEANHKTFRTAANHLTKTFSHTLYDEWEHQLNNPNHPQKLLRPDA
                     AVWASRMLPFFRENRQYCEAFDVRLKEVINYLLANRTALINNRIETIHKRIQNRIALA
                     LQELQQSSRSVQERKEDIEQQDARFREGSGALIARFTEISNFCPRYAEEDIERIRDIF
                     YSLCNDESMYRFIDNRFEDKDEAKRAINKALGNHFESKFRRVMEESTRRFSLEVESVV
                     QAWQKIVPSAQGAARAGMPETDISLSATSDFDAYSAFVGGMAGLTSFGAMAGYVATIS
                     SNLGAYILVGKAAGVLTSLGITSSVTTLPTLVAATGGPVAWGVAIAAVVGLLVYRLFA
                     NWKKALAKSVVKGLESSNTLSNVEADITRYWQDSRNALRASVDSLKNETDAFIRHLYA
                     EANIEYQQQDIAEAEQILNTIKNNLGSEDK"
     gene            7551..8486
                     /locus_tag="IT892_003281"
     CDS             7551..8486
                     /locus_tag="IT892_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136466.1"
                     /translation="MSFLKTLMDSLSAISGSVANASETEKKKDRRSDEEFTDFKDDSS
                     LINYLTKQYIDNELAVDKSKNHWEVFSQHLKPLIHCLKRYEDASLSQRETSQKEQAAA
                     MLEALQQGKELSEHSGNGTIIGRDDYVNGLKKITLSYCQKHVLTMVDFLDNVPDHLCD
                     GKNASTSWQSFRKDASKKRWKNFDQACRDNSLYFSVGKVLFDTTLWGSGKHGIMLGRD
                     DITCLGGEPDKFRVLWSNVTSLWHHKGYLYVNDYKTGFVANDDACKLLELLEEHFDKM
                     KRSEGNLLLAYLGYDRSSQQAIKNAYEADVQQFIE"
     gene            complement(9297..10472)
                     /locus_tag="IT892_003282"
     CDS             complement(9297..10472)
                     /locus_tag="IT892_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136467.1"
                     /translation="MWEEQVRCIVGKELDDICTNCQYIDAVKRHKQQLGAIEEYTQWL
                     KKEPRASYFFLFQLYTRIHNTFFSQKQQLLFTPGGTHCPEPDVTLRDLTLSPGYHSDY
                     APQTIPEMDSSVVVPPTNENTLPPEDTPDNTPAGGNTGQAEKTRNAGLTPIPEKRSGM
                     PPEHLRFATGFPSQPKIAGPREKPMRTVHPDKIYREIIWFCSGYLLKSGPEATRTIIN
                     SVFSEWASINNDYPSPFSWVDSRDSEQCDWLWNAMQVRCVGTPLNPLTPEQKYWFACA
                     TFDNWEGWNEQQVQFLLKSNPRRNRAKFTISPFPALRVKQHKAVLLDELKSAREQQKR
                     RDERADGSVPLKLSGKIHKQLESIARSRGVPPKKMLNEMIEQAHRDFVANEQHKTRS"
     gene            complement(12438..13040)
                     /locus_tag="IT892_003283"
     CDS             complement(12438..13040)
                     /locus_tag="IT892_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001596160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136468.1"
                     /translation="MKPQYQTRYELLHESYQKWLTGFTRHAVSWGVCHPNIHYFHNLT
                     PGWVSFNGEKPKIAIVPRSLHRLIYGSDKRATPPLDDDLVVNLCTSEHLLVHHPMLEG
                     ILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLDDWTENLKRK
                     SEKELGEWIIDRQKQNAALTDLMDQYVLLAYRTTVDDNRN"
     gene            complement(13134..13340)
                     /locus_tag="IT892_003284"
     CDS             complement(13134..13340)
                     /locus_tag="IT892_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HAP3136469.1"
                     /translation="MTTLVSLMDDQMVDMTFITQLTGLTDKWFYKLIKDGAFPAPIKL
                     GRSSRWLKSEVEAWLQARIAQSRP"
     gene            complement(13724..14515)
                     /locus_tag="IT892_003285"
     CDS             complement(13724..14515)
                     /locus_tag="IT892_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136470.1"
                     /translation="MTTRITFNMTSDETLRIVDEYCHTHKLSRSKVIDALLSATAPVL
                     NDINCYYQLAGKLQSRLLNGVYQRDLPHKRNVVSAEKYCLEIWENKLFTKRILEFDSS
                     NGVLYALKHKRHYRRDKMIGRVESRRIKDICEYQMQLSGEKAKYACFIYIERTIYNHD
                     NPSGGTPVKAAVGNAVILLAKDVIYDEYFFDLRQSFFVSVKDLMASGAKGIPETQKYP
                     DVYCWIPLFSINSGVVITPVYKIDPRKPVTVKKPDQITVVCNYRE"
     gene            15573..15731
                     /locus_tag="IT892_003286"
     CDS             15573..15731
                     /locus_tag="IT892_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
                     /protein_id="HAP3136471.1"
                     /translation="MLFTGKVISHARYKLTPEEMEAFNSAVDHRLAELTMNKLYDRVP
                     ASVWKYVT"
     gene            15963..16562
                     /locus_tag="IT892_003287"
     CDS             15963..16562
                     /locus_tag="IT892_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HAP3136472.1"
                     /translation="MKTYNTNPGYEMDPQLLTHFNQHLDSLFGVYSKLLPFRMDFAYR
                     KNTLSYRCACRYAMCAEILRLINEVGEKLVGYAWVMEYTERKGLHIHFVGYLNGQSHR
                     SSYLVSRLMGDIWRRVTGGDGYYHWCRFNKNYPVNINHVIHYSDHKAVNALRYALSYL
                     AKREQKECGIILKCSGLPEKSNRGRPRLGSTLPETYSLV"
     gene            16934..17317
                     /locus_tag="IT892_003288"
     CDS             16934..17317
                     /locus_tag="IT892_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136473.1"
                     /translation="MYAKSFIAFDGNGRLTGARTAQTAPYDRYTCHLCGSALRYHPQY
                     DTERPWFEHTDDGLTEHGQQCPYVRPERREIQLIKRLQQFVPDALPVVRKASRHCRQC
                     HHDYYGERYCTHCHTGHFSEEGVAE"
     gene            17314..17739
                     /locus_tag="IT892_003289"
     CDS             17314..17739
                     /locus_tag="IT892_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136474.1"
                     /translation="MNGIKTGLGITPGEHIISADSALSRNIRQCFCLSCHGRLILQTD
                     AQGAWFEHDLYALSEQQKAACVVLNPEKSHPYIEDMEMFLSPLPVVLEWHCMMCEGLF
                     HGKKFCEACGTGIYCRATCTKYVYRYQPDLYQDCGGALT"
     gene            18084..18251
                     /locus_tag="IT892_003290"
     CDS             18084..18251
                     /locus_tag="IT892_003290"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136475.1"
                     /translation="MSEYNVMLGIREEYFDAPNLGRLILDVWSNPGFVSPDESKQYHP
                     GCGAGSSFTGL"
     gene            18442..18609
                     /locus_tag="IT892_003291"
                     /pseudo
     CDS             18442..18609
                     /locus_tag="IT892_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502603.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
     gene            19587..20766
                     /locus_tag="IT892_003292"
                     /pseudo
     CDS             19587..20766
                     /locus_tag="IT892_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612175.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            20943..>21545
                     /locus_tag="IT892_003293"
     CDS             20943..>21545
                     /locus_tag="IT892_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP3136476.1"
                     /translation="MDNEEVMAKTVEQVAKALDISITTVRLVLGGKAEQYRISAKTQQ
                     RINDYIAENGLVVNHIARSLKLNKTETLGLVIPRLSNLFFSTLAEKLESCCRQAGYQL
                     MIACTYSDSEHENSLVEGLLARNVDGMFVVPSTRETQLHHQKVARKRPLVILDRDFGE
                     SDTTLVVSDNYNGSRKLVQAMTQALDVSPLFFIAGDTQQPS"
BASE COUNT         5797 a         4910 c         5095 g         5743 t
ORIGIN      
        1 aatgcgatag atatatcatg ttgtatcttc tctccgatat atttcgtagc gttgttgata
       61 tctatcgaaa actgtcccca gagtgtacct ctgattatca gaaattgatg agtgaagtta
      121 catcatttgc ccataaacta ctttcttgta gatccgttat tccaaactac gcatatcagc
      181 aagcactatt ttatcttgca gtgatcaata agccatttat agctagtaaa aaatcttctt
      241 ctgatctttc aaagcttcaa catgtcttaa ttaaacgaca tttagagccg ttgagtagta
      301 gtgatggata cctatttgaa ttatctgctc agattagtaa agactaccaa gcaaatgttg
      361 cttttctact ttctcataca aatactactg aagtagtaga ctcaatcgtc gagaaatttg
      421 cttaccgtgg tggtgagttt tggaatagca tttggaaaga gtttgttagg acgaaagata
      481 aagttaggat caacaaattt agatgggcca taccaaaaaa tgagtcgaaa ccaaatggtt
      541 cggaccacta tctttcatca gtgataagtt ttaaggaaaa tccatttaaa tacgaacatg
      601 cgcttctcaa gctaggtata gcattagtta atcttttaga agatacagag aaaaacgtat
      661 ggcaatctga tggaaagcag tattccccac atgaaataaa agtgaaatta gaaggccatt
      721 caacatcatg gactgaatta tggcgccaaa attctattat ttcatgttcg atagataaaa
      781 tagctcaaga tcctcgctat gaaagcccta aatggttggt gaattgtcaa caagccaaaa
      841 atgatgaaaa aaaaatatat tgggtttgca gtgtactaag aagtgctgct ttaggtaatg
      901 tagattacac acagcgaaat gatttaaagc ctgatagagt agagtatgat ggtatccatt
      961 ctcagtttta caagcgacgt atgggaatgt tacatacccc agagtcaatt gttggttcat
     1021 atgcaactat aactgattgg tttgcaagct ttcttcagca tggattgcaa tggcccggct
     1081 tttcatcttc atatataaat caagaagata tattgtcaat taccagcctt ggtgagttta
     1141 aaaaatgctt gttggaaagg ttaggctacc tgaacacgca aatatgcact tcatcgagtg
     1201 ttccgacctt acctactgtt gtcaacagac ctgaattggc atctaactat tttagaattg
     1261 ttacggttca gcaattattt ccgaaggata agcattttca cccttctgac gtaacacttg
     1321 ataatccaga ggtgcgttgg aaacacagag agcaccttgc agaaatttgt aaactgacag
     1381 agcagacttt agatgcaaaa cttaaaactg agtctaggga tcatacaagt accgctgatc
     1441 tgattgtctt ttctgaattg gctgttcacc cggaagatga agatatagta agagcactgg
     1501 catttagaac cagatccatc attttttgcg gttttgtctt ctgtgaacaa gatggtcaaa
     1561 tagttaacaa agctcgctgg attattccag attcgtccga atcggggact caatggcgtg
     1621 ttcgtgatca agggaaattt catatgacca gtggtgaaat gtctctgggt gttcatggat
     1681 atagaccatc tcaacatatt atttctattg agggtcacac cgaaggacca tttaaattaa
     1741 ctggtgcgat ttgttacgat gcgacagata taaagcttgc tgcggatctg agagatttga
     1801 ctgatatgtt tgtcattgca gcgtacaata aagatgtaga cacgtttgac aatatggctt
     1861 cagctctaca atggcatatg tatcagcatg ttattattac gaatactgga gaatatggtg
     1921 gctcaacaat gcaagcccca tacaaagaga aacatcacaa actgatttct catgctcatg
     1981 gaactggtca aatagcaatt agtactgctg atatagattt agcagcattt aggcgaaaga
     2041 ttaaagaata taaaaaaacc aaaacccagc ctgctggatt taaacgaaaa cattaaggat
     2101 tcacatggaa acattagtta agttagctac gattgcttct ccattagtaa gtgctggggt
     2161 agctatttgg gcaattttag ttgccaaatc aactatcagt gaaaacaaag aaatcgctaa
     2221 gaaaaccatt gcagatacgg cctaccaggc atatttgcaa ctagcgatgg agaaccctca
     2281 cttttcgaaa ggttatagtg cagattgtcg acaggagcga gaccctatgt atgaccaata
     2341 tgtttggtac gtggccagaa tgatattctg ttttgagaaa attattgagg ttgaaggaaa
     2401 cctaaaagat agctcttgga cgaatacgct ggaaaaacat ttgaagtttc attctgaaca
     2461 ttttaagaaa acaaaagttg ttgaagagac actctacatt tccccaattt tggatcttat
     2521 aagatgtgcg actaactaag aacctattct aaaagagtgt attccacaca agaagcccac
     2581 tggaaattgt aacatcccaa gatagttttt tgggggtgtt ctctccgtgg gcggtaagtg
     2641 tcaagatcgt tgtcaaccgg tggggctgta aaccattttg tggggcgggt ttatattgcg
     2701 agataaattt ggcatcgcgg ctttaacttc cgttcttcgc tctcagcgga ccttcagctc
     2761 agtgatatcg tccgctctgt gccaggagcg gactgtccaa cccatccctg aagagcctag
     2821 attatgtatg gtaattcagt catcaaaata acgttggtca ccatcacaaa attcacatcc
     2881 tcggatatgg ctcagttcag gaacgctatc gctcaggtga ccgcaataac cacatacatg
     2941 aagctcggtg taatagatga aacactgagt gcaaagatag ccgtctccaa atttacatac
     3001 gctttcagga gtcatgcaat tggtacatcc agcaggaaat acggagagta gctgttcatc
     3061 cacactgtgg aacaactcct catccagcag tttataccta tccgaagtgt agtcgcagtg
     3121 ttcgcattca aaatcactat ctccctcagg tagcaattga ggtatttcgc agtctggaca
     3181 aactagggta atttgcctta cagcactggt gcaaacctta caccgcgtaa cttcaagctt
     3241 acggttttca ttaccggtcg tttcagtccc tgttaccgtc gcatgctgat ggcactcatt
     3301 gcagttaccg atttgaatat tcttttcaga gagctgatcg agttcaggct taacctgttt
     3361 aaaccgcacc tcggcataaa atttgtttcc cctaatcaga cgagtttcac cgaaagccag
     3421 cttccaatta tgtttgacac cgaagataac tttccattca tcccttaata accggttcag
     3481 ggcaaaccag gcgtcagctt gttctttgag tatttgacgt tgttcagcct cggtgaaagt
     3541 ggggtggtag aaatgaacta cgcggttgcg gtgctttctg accttatcaa aagcactgtc
     3601 cgtttctctg tctaggggtc tttcaagtac gtccttaagc ctttcacggg tttcttcgta
     3661 ggtcaccgac tgaaaatcac cggctaggta agcctgcttt tttattggct ttttcgggct
     3721 gcagaccaac gaccagtgtt cgtgcgccag cggaactttc agtaaaatct cgaccgcagt
     3781 ccagaaactg acgacggaga acttcggctt cgaggcctcc aactcttcac gggctttatc
     3841 cagaaaatcc agaccattgt tgatcagcgc ctgcacatcc tgactgagtt cacgaggggc
     3901 gggagtatcg ggtgcagtat cgtcaacatc gaacatcatt atctccttta atcagcttcc
     3961 accacgcagt tgctacagcg cgttatttgt atccagtgta aactggactt ggtagctggc
     4021 agccacatcg agcgcaaaaa accgtaaatt aacttctgta gactcgtact tttcgtgacc
     4081 catgcgtacc cgcaggatct tcgggtgcac gtgaccataa agtaggtgcc taccaaagct
     4141 gtggcgattc agatccctaa actgatgggg tcccaaaaag tatgccatag caagtgtaag
     4201 tatccctaaa atctgcacta ttctcttttt ataaatcctc tgacatgtga attagattgc
     4261 cctaaagtga gcttccgcgc ctcgctcata aggacaacca tactcaaatc tcccacattg
     4321 caggagattt gagtatgaac acgtcaccgt ggaacaaaga ccgtatcata ggccaaaaaa
     4381 gaccacttca gatatctcat atctggggta tccgaatccg acttgaactg gaatgtaaaa
     4441 cgcgcgattt agctctgttc aacatggcct tggacagtaa gcttcgaggc tgtgatctag
     4501 tcaaactcaa agtatctgat gttgcatatg gtagctctgt ttcaagcaga gctacggttc
     4561 tacaacagaa aaccggcagc cctgtccaat ttgagataac caaagggaca agagaagctg
     4621 tttctgcatt gataaagctt ggcaatttac gcagtaaaga ctatttgttc cgatctcggg
     4681 tcggtactaa ccaacacata tcaacccggc aatacaaccg aatttttcat gggtgggtag
     4741 caaaacttgg tctcgaagat tcgctttaca gtacacattc cttgagaaga acaaaacctt
     4801 acctgattta caagaaaact aagaatctca gggtgatcca acttctgtta ggccataaga
     4861 aactggaaag cacagtccgt tatctgggca ttgaagtcga tgatgcgtta gagatctctg
     4921 aatcgattga agtctaaggt tgccagggct gcaacagcag tcctgtgcca gaagcggaca
     4981 ttgctggcac tgaatcatgt taatttatgg taaacagatc acattaatat cacgaatttt
     5041 tcaatactac ggataaccct tatcactaat aagtttcgtc cattcggcat tttatattaa
     5101 caaatcttta atatcaggta gttactaggg atatcgatta tgatctaacg aatggttctt
     5161 ttttttagac aaatacgtct ggattcatca tgcattcatt gctattttag acataccggt
     5221 ctgaagatgg tgggcattgt aatgaacgat aaactgaaaa tgtggcgaga taaggcgggt
     5281 ttaagccaac aggaagtcgc cgagcgggca ggtgaaaatg ttctgtccca aaagcaggtc
     5341 tcgcgtattg aacaggcacc gctgtcacaa aatttagaac tggtgctggc ctaccttcgc
     5401 atcgttgcgc ctgaaaagat tcaggaattc atcactgatt gtttaaagac gcagttaaac
     5461 acgtcctctt taaatcaaaa ctacacacag caaaaagaga atatgatgag aaataaaaag
     5521 gaactgatag agtacctgga aagatcgata gccacgctgt ccaatacttc taatcccttt
     5581 attaaaaaca gcagcatcac caaggatatc gccgagctta aagacaatct taaagatatt
     5641 cacgccaagc ccgtcctgag cgctatgggg ccatcagatg caggaaagtc tacgctgtta
     5701 aactatattt tgggcagcga aattctcccg gcgaaatggc aacccgcgac ctgccttgtc
     5761 acgctactga tgcacactca ggataaacct gattatctgg ataagaataa atcagtcttt
     5821 attttcaaaa atggtttcaa gccgcatatg atttttgatc gtcaaatgct ggcagacttc
     5881 ctgatcgatt caggaggaaa agagctcatc aaaacctatg gcgaaaagga tgaaaacgat
     5941 aatgtcctta atccacaagc ttatatggtt gtggtgtttg aaagtttcgc gattctggaa
     6001 actatctggt tacttgatac gccggggcaa ttaattgaac ccgaaatgta cgatgaaatt
     6061 gatggatgct ccagcgaaga aatccttaac gataaagcca aagccatgag cgcaatttcg
     6121 ctggtagatg gccttatctt cgcatctgct accaccaaat ttatgcgtga cgaagatccg
     6181 gagttcttac aaaatatttt aatgcataag gtgcctctgg aaggagacaa gccgctggcg
     6241 aatttgatca tcttaaaaac ccacagttac gatcaaatta ccgccgaagc gaaccataaa
     6301 acgtttcgta ccgccgcgaa tcacctgacg aaaacctttt cgcataccct gtatgatgaa
     6361 tgggagcatc agttaaataa tcccaaccat ccacagaaat tactacggcc cgacgccgct
     6421 gtctgggcca gcagaatgct gccattcttc cgggaaaata gacaatattg cgaagccttt
     6481 gatgtccgcc tgaaagaggt gatcaattat ctccttgcca atcgaactgc gctgattaac
     6541 aaccggatag agaccatcca taaacgcatc caaaacagga ttgcattagc gctgcaggaa
     6601 ttacagcaga gtagccgttc tgttcaggaa agaaaggagg atattgagca acaggatgcg
     6661 cgatttcgcg agggttccgg cgcgttaatt gctcgcttta ctgaaatcag taacttctgt
     6721 ccgcgctacg ccgaggaaga tattgagcgc atccgcgata ttttctactc gctttgcaat
     6781 gatgagagta tgtaccgttt catcgacaat cgctttgaag ataaagatga agcgaaacgg
     6841 gctattaata aagcgctggg taatcatttc gaaagcaaat ttcgtcgcgt aatggaagag
     6901 agcacccgta ggttcagcct tgaggtggaa agcgtggtcc aggcctggca gaaaatcgtg
     6961 ccttccgccc aaggcgcagc ccgtgcggga atgccggaga ctgatatttc cctttccgcc
     7021 acctccgact ttgatgcata ctccgccttc gtcggaggta tggccggatt aaccagcttc
     7081 ggcgctatgg cgggttacgt ggcaactata tcgagcaatt taggtgccta tattttagtt
     7141 ggcaaagcgg ctggcgtgct gacttcccta gggattacca gttcggtcac gacattacca
     7201 actctcgttg ccgccactgg tggcccggtg gcatggggcg tagctattgc cgcggttgta
     7261 gggctactgg tctatcgact gttcgcaaac tggaaaaagg cactcgccaa atcagttgtt
     7321 aaggggctgg aatccagtaa tacgttaagc aatgtggaag cggatatcac gcgctactgg
     7381 caggattcac gcaacgcgct gagagcgtcg gttgattcac tgaaaaatga gacagatgcc
     7441 tttattaggc atctgtatgc agaagccaat atcgaatatc agcagcagga tattgctgaa
     7501 gctgaacaaa ttttaaatac aatcaaaaat aatctgggta gtgaggataa atgagttttc
     7561 ttaaaacact aatggattcc ttaagcgcga tctcaggttc tgtagccaat gcctcggaga
     7621 cagagaaaaa aaaggaccgt cgcagtgatg aagaatttac cgatttcaaa gacgacagca
     7681 gccttattaa ctacctgaca aaacaatata tcgacaacga actcgcagtc gataaaagca
     7741 aaaatcattg ggaggttttc agccagcacc tgaagccgct catacactgc ctgaaacgct
     7801 atgaagatgc cagcctcagc cagcgtgaaa cctcacaaaa agagcaggcg gcagctatgc
     7861 tggaagccct acagcagggt aaagaactct cggagcacag cggcaacggc acaatcattg
     7921 gaagagatga ctatgttaac ggcctgaaaa aaatcacgct tagctattgc cagaagcacg
     7981 tacttactat ggtcgacttc ctggataacg ttccggatca cctgtgcgac ggaaaaaatg
     8041 ccagtacctc atggcaatcg tttagaaaag atgccagtaa aaagcgctgg aaaaactttg
     8101 atcaggcgtg ccgggacaat tcgctttatt tttctgtggg taaggtcttg tttgatacca
     8161 cactgtgggg ctcagggaag catgggatta tgttagggcg cgatgatatt acctgcttag
     8221 gcggggagcc tgacaagttc cgtgttttat ggagcaacgt aacaagcttg tggcatcaca
     8281 aaggctacct ttacgtgaat gattataaaa cggggtttgt cgccaatgat gacgcctgta
     8341 aattactgga actgctcgaa gagcatttcg ataaaatgaa acgttccgaa ggaaatttgt
     8401 tattagcgta tctgggttac gaccgctcca gccagcaagc tattaaaaac gcttacgaag
     8461 cggatgtgca gcagtttatt gaataacata ctgcgactga cgcggtattt aagataccat
     8521 actgtggcgg gcctgagtgc ccgtcacgct gtcaacatca ataccaaccg gcatagtggg
     8581 tcagtaattc aggatacttt gaaatcctgt taatgttaaa acagtgagca gaggaatgcg
     8641 tgatcaaaac tcgtcacact ggcgctcgaa tatgtgcgca aaaggatacg gctgtttaag
     8701 tagaatcagg aatgccaagg ttgtgagtcc actggtaata ctatcatttt tggaaaacct
     8761 aaaatccggt agtttaatac gcagataaat tttattaaga ttaaaaaata tgaaagcagg
     8821 ctgccgtgat gatgcataat atcctcggga gctatcccgt taataacact acctgctcct
     8881 ttttgattac tacagcaaga tcttcgaaaa gccaataaca agtattttga acttccgctt
     8941 atcgctcaca acggaccttc agctcagccg ctccggccgc ttcatgcaat gaatgtacgc
     9001 agccagtcag aatattaagg tgcggatttc agttcacttg tcagccctgt gatgcaacaa
     9061 gttgcggctc cggttcgtgg gagagatgaa acgacggtag ctgaagttac tgaaatgaag
     9121 aattcagaga gactgaatga tatgcctcac ctttagtgaa tagtgtaaaa acgggagact
     9181 ctcacccggg attatccact catgctcaat gtataatttt cgtgtccctc acaggtaagg
     9241 gccggataca tttgttgagt acgctgcaga attggtaacc ggggaccctg ccgtctttaa
     9301 ctccgggtct tatgctgctc atttgccaca aaatcccggt gcgcctgctc aatcatttca
     9361 ttcagcattt tttttggggg gacaccacga cttcgggcaa tactttcaag ctgtttgtgg
     9421 atttttccgg acagtttcag cgggacggaa ccatcagcac gctcatcacg ccttttttgt
     9481 tgctcccggg cacttttcag ctcatcaaga agaacagctt tatgctgttt aactctgagt
     9541 gccgggaagg gacttatcgt aaacttcgct ctgtttcgtc tgggattact tttcagtaaa
     9601 aactgtacct gttgctcatt ccagccttcc cagttatcaa acgtggcgca ggcgaaccag
     9661 tatttctgct ccggggtaag gggattcagc ggggttccca cacaccggac ctgcatggcg
     9721 ttccataacc agtcacactg ttcactgtcc ctgctgtcca cccacgaaaa gggggagggg
     9781 taatcattgt ttatgctggc ccattcagag aatactgagt tgataatcgt cctcgtagcc
     9841 tctggtccgg atttcagcag gtaaccggag cagaaccata taatttcacg gtagatttta
     9901 tccggatgca cggtgcgcat cggcttttct ctgggaccgg caatcttcgg ttgcgatgga
     9961 aaccccgtgg caaaccgcag atgttccggg ggcattcctg aacgtttttc aggaatgggt
    10021 gtgagtcctg cgtttctggt cttttccgct tgtccagtat tgcctccggc cggagtgttg
    10081 tcgggagtat cttccggagg caaggtgttt tcattagtgg ggggaacaac aacagaactg
    10141 tccatctccg gaatggtttg aggggcataa tcactgtggt agcccgggga aagcgttaag
    10201 tcccgaaggg tgacatcagg ttccgggcag tgagtgccac cgggagtgaa caggagttgt
    10261 tgcttttggg agaaaaatgt attgtgaatg cgggtataca gctggaacag aaaaaaataa
    10321 gatgcccgtg gttctttttt taaccactgt gtatattcct ctatggcacc gagctgttgt
    10381 ttgtgccgtt ttacagcatc gatatactga cagttggtgc agatatcatc cagttccttt
    10441 cccacaatac acctcacttg ctcttcccac atttgcatat tttaagaaag caaacaaaaa
    10501 cctccgtaca tgaggtacag aatgtacaga acaatctacc aagtactggc gtcagaaaac
    10561 ctccgggccg cctgcacttt ccggaatgcg ccggttatga aaaaccggaa attcagtctc
    10621 tgttgtaaga tgtaccctct gatactacgt tttcgttttc tctgtgtatt taactcactg
    10681 tatttattgt ctttttaagc ttgactgata ttccgatcat agtgtgccgg atatacatcc
    10741 cgtaatcttc tcatttttat ataaaaatac ctgcactctc ttcagcgcat ctgtctcctt
    10801 taagtaaaaa atgttttcac gtattgctgt aaattcattt taaatcagtg tattaccttg
    10861 atattgctgt ctcctggtgt gatgcgtaat cgttttgtct ttctggatga tgctggtgct
    10921 tccgggtgca ttctcctctg tacatgcaac agtttgtcat cgccacgttc ccaaaaaaag
    10981 catataaaaa tgaatcgaat ttgataattt tttcaatcgt ttttcatagg aatttcgtag
    11041 ggtattctcc gctataacct ccatatttgc tgcctttttc tccataaatc gtatgcaata
    11101 tagcctgtct gtcaagacct cttctttgcg gttgaggaga cgatctcatt tctggtcttt
    11161 tccgggagag agacggccag atgagcgagc cggatttact gccagaggta ctccccgcgg
    11221 cagaaaatag tgctcctgtt tccgcaatcc gggatcggca acgtcccatg gttaatgcca
    11281 cttgcagcgt caggcactgc aggtttacgt cgtgatctga tttcttctgc acttatcccg
    11341 atcacggaag ttccccctgc gaagacatcg gttcctgccg acatctcaca ataccgccag
    11401 gcagtcatgc agtaacaccc gcaatgcggt ctgcggtttt aagcgcactc tcctgtattc
    11461 agtgcaccga taatgcatca tagaaagtcc ggggtgagtt actgaatgtc tgttaagtgg
    11521 tgccgtgggt agagctgctt acttttccac agttaactgc agtcattcag gatgctcagg
    11581 agagaatatg tcaacgccac gggccgggcc attttcatgc cagtcaggat attttcaata
    11641 ctgatgctgt ctgcttttca ccatcctcac agacaggcgt tgcgttttgg gtcatcacca
    11701 cagctttacg tttctctttt aaccggtaac gctctccttt gatattcagc gtggttgact
    11761 gatgcagcag tcaatccagg agcgctgttg tccggcaacc accatatcaa cttcttcccg
    11821 ggtgtggcgg agagcaggta tcctggctga gtttcgaagc cggccattgc tttcgtctac
    11881 gggactcccc tgctcagtga gcggcaacac cggtatttac cattatacgg ggccggggct
    11941 gctctatatt ttcgtgcaac gtgagaatac ctctgtgcct gtggcttttc agcagccttt
    12001 gtcgttgtga gatcctctgg ttgagtggca ccatgatgtc cccgaaacgc ccccgactcc
    12061 cacagataac gcaactcact gtccgtcact gtaaccggca acacccgtaa cctgtgccat
    12121 acagacggag cccggtcatg tgcagagacc ggtaaaattc gttactacaa ctgttcctga
    12181 atatctgacg aagaaacatt cagccgtaac atccagccgt gtacatctct tccgcggtgc
    12241 agggagcgct gtcgccatgt acttattgtc atcaggatga ggcatgtacc gcagcatgcc
    12301 agatcagcaa tgactggatg cccttaagac atccgtcatg gctcagtatg atgacgacga
    12361 acacgtcctg caggtgagca tgcggggccg ggagcagcat ttccgtattt tgtcgcacct
    12421 tccggaagca accggcatca gttacggtta tcgtcaaccg ttgtgcggta tgccaggagc
    12481 acgtactgat ccatcagatc cgtcagtgct gcgttctgct tctgacggtc gatgatccat
    12541 tcccccagct ctttttctga tttccgtttc aggttctccg tccagtcgtc aaggctgttt
    12601 ccggtcatta aatcaagcca gcagagccag accagtttga ggcgcagttc cgtgccacca
    12661 aactgacgga agagactgat cagtttattt gccagcgaac gctgcctcag acgttcacat
    12721 tcagacagca gaatgccttc cagcatcgga tgatgaacca gcagatgttc gctggtacat
    12781 aagttcacca ccagatcatc atccaggggc ggcgtggccc gtttgtcaga gccataaatc
    12841 agccggtgca gactccgggg gacgatggca atcttcggtt tttcaccatt gaatgacacc
    12901 cacccgggcg tcagattatg gaagtagtgg atattcggat gacacacgcc ccaggatacg
    12961 gcgtgccggg tgaagccggt cagccatttc tggtagcttt cgtggagcag ctcgtaacgg
    13021 gtctgatact gtggtttcat tttcatattc ctcacggggg ataacaggca gcagactgcc
    13081 gccggcaggc cggagattgc gtctgctgtg ggcgaagggc cagtggttaa aaattacgga
    13141 cgggactgtg caatacgcgc ctgcagccag gcttccactt cacttttcag ccagcgggag
    13201 ctgcggccga gtttgatggg agccggaaag gccccatcct tgatgagctt gtaaaaccac
    13261 ttatcggtca ggccggtcag ctgagtgata aacgtcatat cgaccatctg gtcatccatc
    13321 agcgaaacta gggtggtcat aaaaatctcc tccggatgtt gttaatctca gccggcgttg
    13381 atgatgaaaa caacgcacca ccttcaccgg cataacaacc ggggagaaac gtaaaaaatc
    13441 agtaggggaa tattcctgcc aggagagaaa ctgttgtgta caggcaatac aggttgtctg
    13501 ttttgtcagt gaagccggta taaacggaag atgattttgt gttgccggaa tatgggatgg
    13561 cgttttgccg tgacgggatc agtattttca gtgatgatta ttactgtgca ggggagtacc
    13621 ggagataaac cacgccctgt acctgccaga gcggaggttt gtatttactg aacggaagat
    13681 aaagcgaggt aaacactgtt gcggtgagcg gagaagactg agattattct ctgtaattac
    13741 aaacaacagt gatctgatcc ggttttttta ccgttacggg tttccgggga tcaattttat
    13801 agaccggggt aatgaccacg ccggaattta tggagaaaag cgggatccag caataaacgt
    13861 ccggatattt ctgtgtctcc ggaatacctt ttgcgccaga ggccatcaga tctttaacgc
    13921 tcacgaaaaa tgactgccgc agatcaaaaa agtactcgtc atatatcacg tcttttgcca
    13981 gcaggatgac tgcattacca acagccgctt ttacaggtgt cccaccggat ggattatcgt
    14041 gattgtatat tgttctttca atataaataa aacaggcata ttttgccttc tccccggaca
    14101 gttgcatctg gtattcgcaa atgtctttga tacgccggct ttcaacccgt ccaatcatct
    14161 tatcccggcg atagtgtctt ttatgtttca gcgcgtacag aacaccattt gaactgtcaa
    14221 actccaggat tcttttggtg aaaagtttgt tttcccagat ctccagacaa tacttctctg
    14281 cactgacgac attgcgtttg tgaggaagat cccgttgata cactccattt aataagcgtg
    14341 actgcagttt gcctgcaagt tgataataac agttaatatc gttaaggaca ggtgctgtgg
    14401 cgctgagtaa tgcgtcgatt accttagagc gcgaaagttt gtgggtatga cagtactcat
    14461 ccacaattcg cagcgtctca tcactggtca tattgaaagt tatacgtgtt gtcatgatga
    14521 aattttctgt taatcatact ggttgatatg cataacattt cataaaaaat acttttaatt
    14581 catataattg atttttttga ctggttttat cctcgtgtgg tggaaagtag tgttactgcc
    14641 actgtagtca gcataactct atcacacaga accaccgaaa atgaagcatt gctcaggggg
    14701 aagctgccac tcgtacgagt tctctgagca atgataacca gtatttttcg ttttgggcga
    14761 tttgtttatc gttacagcta aaaacagtta atgtaccatt aaaaaataat aaaggttaat
    14821 tagtattatt tatagaagta tgtttatgta attctaccgg gtaaatgaac tctgtcattg
    14881 taccttgtaa ttctatcctg taattctacc tcgtaaatac accttgtaac caggtcctgc
    14941 agaagtctgt ctcatcgaac aatattcctg tgcagcgata ttctctgtag tagtacttgt
    15001 aactctgccc ttaactctct cttcagtaat gtagtcccgc aacacctgaa tataaatctg
    15061 taatgttcac acactgactg taacgtgctt tgttaagtaa tgtctgctat tttttttctg
    15121 ttattttttc ctgttgtttt ctgtattttg ttgtatggtg taataactat tctgaacccg
    15181 tcatcacctt tatagctaag agtatgactt cgccagtgtt gatactgtgg ataacggtga
    15241 ttaaggaatt actgttaatg atctgttcct gcagctcacc tgatgagttt tggtagtaat
    15301 acgtaaaaga gtatgcctca tgtcattaaa aagtcttccg gagtgttgtt taaccctgta
    15361 cctctgttac tcatgtagta cgttgcggaa agctacgtta attgtaatat ctggttatgg
    15421 cgttatgcct tcagtattaa aaacatcttt taccggagaa acagggaagt ggaaaggctt
    15481 tcgggataac atcaggccat tatgacgata ttacgttaat cacagtacaa gataacgaga
    15541 gggtaatgga attttaaacc agagtagttc cactgttgtt cactggaaaa gtgatttccc
    15601 acgcgcgtta taagcttact ccagaggaga tggaagcctt caactctgcg gtcgatcacc
    15661 ggctggcaga actgaccatg aacaaacttt acgatcgtgt tcccgcttca gtctggaaat
    15721 atgttacctg ataaatgttt ctgatgaagt acagtcgtca caatgacatc acttcagata
    15781 ttatctgcgc tgtgattgac tgtcacgtat gccgttctct gtatggttct gatacccggg
    15841 tgtggtccca ctttctctgt ggcgcccggg gagttgtgaa cctgcacgtc ttcgtgtgat
    15901 aacgttttct tcaaaaatta cgccagcgct tcttcctgtg ttacagaaca cgaggaagaa
    15961 acatgaagac ttacaacacc aatcccggtt acgaaatgga tccccagctc ctgacacact
    16021 ttaaccagca tctggattca ttattcgggg tatattcgaa actgttaccg ttcagaatgg
    16081 attttgctta ccgaaaaaac accctcagct acagatgtgc ctgcaggtac gccatgtgcg
    16141 cggagatact gcgactgatt aacgaagtgg gagagaaact ggtcgggtat gcctgggtaa
    16201 tggaatatac ggaacgtaaa gggcttcaca ttcattttgt gggctatctg aacggtcaga
    16261 gccacaggag ttcgtatctg gtatccagat tgatgggaga tatctggagg cgggttaccg
    16321 ggggggatgg ttactaccac tggtgccggt ttaataaaaa ttatccggta aacattaacc
    16381 acgtcattca ctattcagat cacaaagcgg tgaatgcctt acgctatgcc ctcagctacc
    16441 tggccaaacg agaacagaaa gaatgtggca tcatcctgaa atgcagcggg cttcctgaaa
    16501 aaagtaaccg gggtcgaccg cgactgggca gcaccctgcc ggagacttat tctctggtgt
    16561 aagaccctga acgacaacta cgggctggcg ctaattgtta cggtcggttc cggaggccac
    16621 ttcagggact ctgcgcattt tttacgacat ggctattccg tatgaaccat acggagattt
    16681 aaccatggca cattctttac cattccttcc ggcaaccgat acagcgcatc ccccgatgtc
    16741 catccctgcc tgctgacagt tttttacgcc ggtgggccat tgtgtgacaa ccacagtgct
    16801 gtaacagcaa ccagcctgct ttacccaaac tccagtccag attttaactg aaccgccatt
    16861 caccccctga ccacactgcc cgtaccggga cagctgttgc ctgcgtgtcg tctggcggct
    16921 gaggaatatg acgatgtacg caaaatcctt tattgcattt gatggcaacg ggcgtctgac
    16981 gggtgcccgt accgcacaga ctgcacctta cgatcgctac acttgccacc tttgcggcag
    17041 tgcgctcaga taccacccgc aatacgacac tgagcgtccc tggtttgaac acactgacga
    17101 cgggctgacg gagcacggtc agcagtgccc ttatgtcaga ccggaacgca gggagataca
    17161 actgattaag cgtctgcagc aattcgtacc ggatgcctta cccgtggtgc gtaaagccag
    17221 ccggcactgc agacaatgtc atcacgatta ttatggggag cggtactgca cgcactgcca
    17281 taccgggcac ttcagtgagg agggggtggc agaatgaacg gtataaaaac ggggctgggg
    17341 atcacgccgg gtgaacacat aatcagtgct gattctgcac tcagcagaaa tatccggcag
    17401 tgtttctgcc tttcctgtca tggccggttg attttgcaga cagatgctca gggggcatgg
    17461 tttgagcatg atttatatgc cctgagcgag caacagaagg cagcctgcgt ggtgctgaat
    17521 ccggaaaagt cccaccctta cattgaggat atggagatgt ttttatcgcc attaccggtc
    17581 gtgctggagt ggcattgtat gatgtgcgag gggctttttc atgggaagaa gttctgtgag
    17641 gcctgtggta cggggattta ttgcagagca acatgtacga agtatgttta caggtaccag
    17701 ccagatttgt accaggactg cggaggtgca ctcacttaat ccgaaatgcc cgctctgctc
    17761 agggcgttca ggctgactat caatggcata cattttatcc ggtgtttcgc acccacaccg
    17821 tgcaacgact cgacaccgga tatccgcagt cccgcttacc tgaataaaac ccgggggatt
    17881 gattgtgtac tgtggtgtga aatcgcaccg tgatcgctga ttcgccgaat ccgcactgtg
    17941 gtgtcaatca accacacgcg agagtcgtct caggcttcgc ctgcctcagg acgatttctg
    18001 catagctaat tcccggggca acatttatag aggcgctgtg cgctctgatg gtcgccactt
    18061 ctgacccgga ccatgctcct gatatgtcgg aatataatgt gatgttaggc atcagagagg
    18121 aatatttcga tgcccctaat ctggggcgtt tgattctgga tgtctggagc aatccgggct
    18181 ttgtgtcacc ggacgaatca aagcagtacc acccgggatg tggcgctgga tcgtcattca
    18241 ccggactgtg aagacatact taaagagctg atatgggcgt tcagtgattt cgcccgcgat
    18301 catcgtggtg tgtgtgatcc gaaagcccgt tacctcgccg gtaatccttg gtatccgtag
    18361 caggccagct ctgaaagcac agctcagcag attccccgca ttcgcacaac cttcataaat
    18421 ctcacagagg acattgtggc catgttgacc acaacaagcc acgacagcgt attgctgcgt
    18481 tccgatgatc ccctgctcga catgaactac atcaccagtt tcaccggcat gaccgacaaa
    18541 tagttttata aactgatcag tgaaggctat tttcaaactg ggcggtacaa aagcgaagtg
    18601 gagcagtgga tgcagcagcg aatagaggga gcgtgggggc agcaggatga aatgtgttgt
    18661 gatgccggta cgctggcatt gtgcaaaatg ccggcgctac tattgtggaa atcagccctg
    18721 tccctggtgc tggcgatact ccctgcagac attctccggt cagccaatag gttgttgctc
    18781 tttcctgatc gattcgtcat tccattcttt ttgtttataa tgggcattac attggtgttg
    18841 gcgtgtttac ctgcgtgtct gcaccggttc agtaaaatta gaaaagttca gagtcgggga
    18901 aaatccggcg ttttgttcag caggcggtgg atcactggcc aaatctgttg gcatttcact
    18961 tcacgttcca ttcaacagaa ggaaacatct acgggcaaca gattcatgca ttctgcactt
    19021 ccttttacca acagatacac aaacgtatta ctgcacgtac tcacacgacc agtccatcat
    19081 cgccgttggt gttacactgg ctgctggaac aacatggagg agcagtaata cgatgcgtat
    19141 tgctcctcag ccagacgagt atttgtcatc cgcgagccag cgtcacggtt gatgaagaat
    19201 gttcgaaact ggtggattta ttgcaacaga tctggccagt gataagcact ggcggacaat
    19261 gccaagtgga aaggtgtttt caggttgccc ggggtgatac atcaaagcaa tacgttgcgt
    19321 taaaaacaga tgcgttgtcg tttgctgtgt cggatcacaa atcatccggt gcagagtagt
    19381 attctggctg tattctggta aatcagcgta ttatcgatat attatcgtac tatcagaaac
    19441 cgtatcgtct gttgatggct agactggccc ccctgaatct tcagacaacc aatatcactt
    19501 atttaagtga tagtcttact actagttttt agactagtca ttggaaaaca gatgattgat
    19561 gtcttaggac cggagaaacg cagacggtgt accactcaga aaaaatcgat attgttcagc
    19621 agagccttga accggggatg acagtctctc tcgttgcacg gcaacacggt gtggcagcca
    19681 gttatttctc tggcgcaagc aataccagga aggaagtctc actgctgtgg ctgccggaga
    19741 gcaggttgtt ccggcctctg agcttgctgc cgccatgaag caaattaaag aactccagcg
    19801 cctgctcggc aagaaaacga tggaaatgaa ctccttaaag aagccgtcga atatggacgg
    19861 gcaaaaaagt ggatagcgca cgccccttat tgcccgggga tgaggagtaa acgtcgtcag
    19921 tcgttgtcgc cgggtgtcgc atgagcagtt gcacatcatt ctcagacgaa gtgatgactg
    19981 gaaggatggc cgccgcagtc ttcacactga tgatacggat gtgcttctcc ggatacatca
    20041 tatcatcgga gagttgccca cgtatggtta tcgtcgggta tgggcgctgc ttcgcagaca
    20101 ggcagaactt gatggtatgt ctgcgatcaa tgccaaacgt gtttaccgga acatgcgcca
    20161 gaatgcgctg ttgcttgagc gaaaacccgc tgtaccgcca tcgaaacagg cacataccgg
    20221 cagagtggcc gtgaaagaaa gtaatcagcg atggtgctct gacggggtcg agttccgctg
    20281 tgataacgga gagagactgc gtgtcacatt cgcgctggac tgctgtgatc gtgaggcact
    20341 gcactgggcg gtgaccaccg gcggcttcaa cagtggaaca gtacatgacg tcatgctggg
    20401 agtggtggaa cgtcgcttcg gcagcgacct tcctgcgttt ccagtggagt ggctgatggt
    20461 taatgctacc gggctaatga aacacaccag ttcgctcgga tgttggggct tgaaccgaaa
    20521 aacacagcgg tgcggagtcc ggagattaac ggcatagcag agagcttcgt gaaaacgata
    20581 aagcgtggct acataagtat catgcccaaa ccagacgggt taacggcagc acagaacctt
    20641 gcagaggcgt tcgagcatta taatgaatgg catccgcata gtacgctgga ttatcgctct
    20701 ccacgcgaat atctacggcc gcaggcctgt aatgggttaa gtgataatag atgtctggaa
    20761 atataggggc aaatccaagg catagaaacc gtttttttga agataaatac aataatccac
    20821 ggtcagcagt gctaagtttt ccctattatt cttaccattc gtgatgccat tccccccaca
    20881 aatccctgtt gctaataccc aactaactcg aattagttta caataaacgc atcacgttct
    20941 gtatggataa cgaagaggtt atggccaaaa ccgttgagca agtcgctaag gcgctggata
    21001 tctccatcac cactgtgcgc ctagtcctgg gcggcaaagc ggaacagtac cgcatcagcg
    21061 ccaaaacgca gcagcgcatt aatgattata tcgccgagaa tggactggtc gttaaccaca
    21121 ttgcccgcag cttaaaactc aataaaaccg aaaccttagg gctggtgata ccgcgcctgt
    21181 cgaacctgtt tttctccacc ttggcagaga aactggagtc ctgctgccgc caggccggct
    21241 atcagttgat gatcgcctgc acctacagcg acagcgagca cgaaaacagt ctggtggaag
    21301 ggttgctggc acgcaatgtc gacgggatgt tcgtggtgcc ctcaacccgc gaaacccagt
    21361 tacatcatca gaaggtggcg cgcaaacgcc cgttggtgat cctcgaccgt gatttcggcg
    21421 agagcgacac cacgctggtg gtgagtgata actacaacgg cagcagaaaa ctggtacagg
    21481 ccatgacgca agcgctggac gtctcgccgc tgttctttat cgcgggggat acccaacagc
    21541 cttcc
//
LOCUS       DACAOP010000082        21496 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.082, whole genome shotgun sequence.
ACCESSION   DACAOP010000082 DACAOP010000000
VERSION     DACAOP010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21496
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.082"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            219..737
                     /gene="tssB"
                     /locus_tag="IT892_003294"
     CDS             219..737
                     /gene="tssB"
                     /locus_tag="IT892_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HAP3136477.1"
                     /translation="MSKKFEGSVAPRERINISYVPKTDGQTAEVELPLNMLVVGDTGN
                     TQETSSLDERQAVSVNKHNFGAVMAEAAIGLNFTVPATLKGSTTDDELNVALNIKSLD
                     DFSPDSVARQVPEVNKLLELREALTALKGPMGNLPAFRTQLQALLENEESREQLLKEI
                     GQVSNKQPPLFH"
     gene            754..978
                     /locus_tag="IT892_003295"
     CDS             754..978
                     /locus_tag="IT892_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136478.1"
                     /translation="MTAHKNISGTYHLSVADILQVVYQVCFSPSVEINQDGVAALITT
                     LDRRISDLLDEIIHFCEFQQSASHWQRVLH"
     gene            1029..2504
                     /gene="tssC"
                     /locus_tag="IT892_003296"
     CDS             1029..2504
                     /gene="tssC"
                     /locus_tag="IT892_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001501045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
                     /protein_id="HAP3136479.1"
                     /translation="MSLQEEELVSSHAGQPEQASSLLDQIMAQTRIQPGSEGYDVARQ
                     GVTAFIASILQSTASAEPVNKLVVDSMIADIDERISRQMDVIIHAPAFQQVESFWRSL
                     KTMVDRVDFRENIKVNVLHVTKQELLEDFEFAPEIIQSGFYKHVYSSGFGQFGGEPIA
                     AVLGAYEFKNTAPDMKLLQYVSAVGAMAHAPFLSSVSPEFMGLNSWTELPNIKDLYAI
                     FEGPAYTKWRALRDSEDSRYLGLTAPRFLLRQPYSPTDNPVKNFNYYEDVSQNHEDYL
                     WGNTAWMLACNIADSFAKYRWCPNIIGPQSGGAVKDLPVHLFETMGQIQAKIPTEVLV
                     TDRREFELAEEGFITLTMRKDSDNAAFFSANSVQKPKHFPGKDAETNYKLGTQLPYLF
                     IINRLAHYIKVLQREQLGSWKERSDLERELNTWIRQYVADQENPPADVRSRKPLRAAK
                     VEVMDVEGEPGWYQVALSVRPHFKFMGANFELSLVGRLDRE"
     gene            2511..2924
                     /gene="tssE"
                     /locus_tag="IT892_003297"
     CDS             2511..2924
                     /gene="tssE"
                     /locus_tag="IT892_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HAP3136480.1"
                     /translation="MIPDRERTTGSLFERMEASSARNRQGGSIHSLRQSIRQNLRNIL
                     NTRSGSCRGAPELGIDEPEGAENFRESMSRAIEQCIERYEPRISHAEVQVVVSSASSP
                     LDMTFHITAWVTFNETHEVLEFDMAPNGSQHYRVD"
     gene            2928..4778
                     /gene="tssF"
                     /locus_tag="IT892_003298"
     CDS             2928..4778
                     /gene="tssF"
                     /locus_tag="IT892_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HAP3136481.1"
                     /translation="MEFEERYFREELDYLRQLSKLLATEKPHLARFLAEKDADPDIER
                     LLEGVAFLTGNLRQKIEDEFPELTHGLIKMLWPNYLRPVPAMTLIEYTPDMDKSSVPV
                     LIPRNEQFTTNAGEIRVDEVLPSDAKKEEPPPCTFTLCRDIWLLPVRLEQIENRSTTR
                     NGVINITFSVAPGTDFRTLDLNKLRFWLGNDDNYTRDQLYLWFCEYLQGADLTVGEQH
                     LRLPEFMLKAVGFEPQDAMLPWPKNVHSGYRILQEYFCYPDAFLFFDLCGCPALPDGL
                     QAEFFTLQLRFSRPLPVDIRLRRDSLRLYCAPAINLFIHHAEAITLDNRRADYPLVPS
                     RHYPQHYDVFSVNSVVSQVQDMFRKKDLGRPVSTQAARQWPAFESFSHQMEYSRKREV
                     VYWHHRTKTSLFHRGFDHTLAFIHADGSYPSDESLLSNEVVSVSLTCTNRELPSQIRS
                     GDITGTTGKNAAVASFRNITRPTQPLWPVIDGSLHWSLLSAMNLNYLSLLDTDALKQV
                     IANFDRHAIHHPQTARLSQQKLDAIERLETRPVDRLFTGIPVRGLASTLYLHPEPFVC
                     EGEMYLLGTVLSHFLSLYASVNSFHMLTVVNTESQETWKWTERIGQHPLI"
     gene            4742..5824
                     /gene="tssG"
                     /locus_tag="IT892_003299"
     CDS             4742..5824
                     /gene="tssG"
                     /locus_tag="IT892_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HAP3136482.1"
                     /translation="MDGKNRAASSYLSPGNPPADKEQNDPLAQVFHNACSYNFFAMAE
                     LLHRLAKGEKGTPELSLRDDPAQETLRFSADASLAFPCSDISALKRDTSGAFRMTTTF
                     MGLQGSQSPLPGYYLDHLAWKAVHEQSPVGDFLDMFSHRLTQFVWHIWRKYRYHISFR
                     NGGVDAFSQRMYSLVGLGHRQLRDKLAINHSKMLAYSGILANPGRSPEIICGLVSHCF
                     DLSEVTLQNWQRRKVDIEPDQQNSLGSYSLKNGEKLAGRSVLGNFVLGTRVPDLSGKF
                     QLSITSLTRKQFLSFLPSGENFLPLTMFVSFILRDQLAWDLHLGLAPEQVGAMRLGDN
                     KSALLGWTSFLGTPEERPSVTIRVRS"
     gene            5849..7129
                     /gene="tagH"
                     /locus_tag="IT892_003300"
     CDS             5849..7129
                     /gene="tagH"
                     /locus_tag="IT892_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated FHA domain
                     protein TagH"
                     /protein_id="HAP3136483.1"
                     /translation="MPEEKLQTLSLQVINGSELESGRAARCLFTQQGNVGHGPECHWS
                     VQDRQQSIPAQAFTVILHDGTFCLRPQTAQLWLNQAKVTATSDLIQLRQGDEIQIGRL
                     MVRVHLNRGDIPHYDEEMATPETIVTNRDMLTDTLLSTEGAPHYPGMTHRHQLADSVV
                     NGFSADPLQALQSESLITTGDPLSGIAAVRPSAPLSDPASNGGINTPFMDLPPIYASP
                     GDRNDDVSAAEMAQRHLAVTPLLRGLGGSLTMSNSDDADDFLEEAGRTLQAAIKGLLD
                     LQQQRNSLSDKHLRPLEDNPLRLNMDYATALDVMFAEGKSPVHLAAPAAVSESLRNVR
                     HHEEANRAAIVESLRVLLDAFSPQNLLRRFVQYRRSHELRQPLDDAGAWQMYSHYYEE
                     LASDRQQGFEMLFNEVYAQVYDRVLREKQREPEA"
     gene            7126..7650
                     /gene="tssJ"
                     /locus_tag="IT892_003301"
     CDS             7126..7650
                     /gene="tssJ"
                     /locus_tag="IT892_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HAP3136484.1"
                     /translation="MNRKAFLACVLMCVILTGCETAKKISEVIKNPDIQVGSLKEQPS
                     EITVTLLTEPDTNTNAEGESAAVDVQLVYLTDDSKLLAADYDQIASTPLPDVLGKNYI
                     DHQDFNLLPDTIKTLPPVKLDEKTQFIGVVAYFSDDQATEWKQIETVEGTGHHYRLLV
                     HVRQSSIEMKKEDE"
     gene            7653..8984
                     /gene="tssK"
                     /locus_tag="IT892_003302"
     CDS             7653..8984
                     /gene="tssK"
                     /locus_tag="IT892_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HAP3136485.1"
                     /translation="MATTRNKVMWQEGMLMRPHHFQQQQRYNDYLDNQRFRAMNDLSW
                     GFTELTLNNELLAQGKIMIDSASGTLPDGTVFSIPDQDALPDPLHPQNFPDERSRNIY
                     LALPVASDVRNEISDGRRIGRYRLNYADVRDLHSEEGDARTLTLGQLTPRIMSGAEDM
                     SAYITLPLCRISNRHADGSLTLDDDFIPSCQNIQVSKKLRVYLKEVQGAIGGRASDLA
                     NRIGSPAQSGIADVAEFMMLQLLNRNQTRFTHRARRSQLHPEDFYLDLAGLLGELMTF
                     TEPSRLPCPLDVYDHHDLTKTFKTLLPEVKRALHTVLSPRAVNLPLHLRDGIWQADIH
                     DTELLQSATFVLAVAANVPVDQIQRQFIQQSKISSPEKIRNMVSVQIPGIPLRALMVA
                     PRQLPYHSGFSYFELDKSGQAWTEMAAAGAVALHVSGSFPDLNMQLWAIRG"
     gene            8989..9750
                     /locus_tag="IT892_003303"
     CDS             8989..9750
                     /locus_tag="IT892_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DotU family type IV/VI secretion system protein"
                     /protein_id="HAP3136486.1"
                     /translation="MDEGSLSLPPFTGHDEKSQRNYHLALRGNSLNPMIDAATPLLGM
                     VMRLSTMNSQTMPEHLFAQVVTDVQAVEQLLQEQGYEPGVIISFRYILCTFIDEAALG
                     NGWSNKNEWIKQSLLVHFHNEAWGGEKVFILLERLIREPKRYQDLLEFLWICFSLGFR
                     GRYKVAAQDQGEFEQIYRRLYHVLHKLRGDAPFPLLHQDKKTQGGRYQLISRLTVKHI
                     FCGGVVVLALFYLFYLLRLDSQTQDILHQLNKLLR"
     gene            9759..12524
                     /gene="tssH"
                     /locus_tag="IT892_003304"
     CDS             9759..12524
                     /gene="tssH"
                     /locus_tag="IT892_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HAP3136487.1"
                     /translation="MIQIDLPPLVKRLNLFSRQALEMAASECMSQQAAEITVSHVLIQ
                     MLAMPRSDLRVITRQGDIGMEELRQALTVENYTTARSADSYPAFSPMLVEWLKEGWLL
                     ASAEMQHSELRGGVLLLALLHSPLRYIPPAAARLLTGINRDRLQQDFVQWTQESAESV
                     VPDADGKGAGTMTDASDTLLARYAKNMTADARNGRLDPVLCRDHEIDLMIDILCRRRK
                     NNPVVVGEAGVGKSALIEGLALRIVAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEK
                     RFKGLMAEVISSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKPALARGELKTIAATT
                     WSEYKKYFEKDAALSRRFQLVKVSEPNAAEATIILRGLSAVYEQSHGVLIDDDALQAA
                     ATLSERYLSGRQLPDKAIDVLDTACARVAINLSSPPKQISALTTLSHQQEAEIRQLER
                     ELRIGLRTDTSRMTEVLVQYDETLTALDELEAAWHQQQTLVREIIALRQQLLGVAEDD
                     AAPLPDADTVEDTQPESESEQDNTGAVPADEADREQPEETAETVSPVQRLAQLTAELD
                     ALHNDRLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLTKWLGDTIKGQDLA
                     IASLHKHLLTARADLRRPGRPLGAFLLAGPSGVGKTETVLQLAELLYGGRQYLTTINM
                     SEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQ
                     AFDKGEMADGEGRLIDCKNIVFFLTSNLGYQVIVEHADDPETMQEVLYPVLADFFKPA
                     LLARMEVVPYLPLSKETLATIIAGKLARLDNVLRSRFGAEVVIEPEVTDEIMSRVTRA
                     ENGARMLESVIDGDMLPPLSLLLLQKMAANTAIARIRLSAVDGAFTADVEDAQNDESV
                     TKDETVL"
     gene            12521..13264
                     /gene="tagO"
                     /locus_tag="IT892_003305"
     CDS             12521..13264
                     /gene="tagO"
                     /locus_tag="IT892_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated protein
                     TagO"
                     /protein_id="HAP3136488.1"
                     /translation="MSRLRVFRQTGWFIAGLMTGLPATAAPAEASSMAGVAVAVATTT
                     PPDATATLQAIQSCRRESAALERLDCYDRLLAPLSPSGFDGALVKAGFVGEAWTRATE
                     QEKRREGNTTELLVTQVPGERPTVVITTPAIGHVPPRPVLMFSCVDNITRMQVALMHP
                     LDVHDIAVTLNADNRALRSHWFVRENGTLLESSRGLSGIDEIKQLFGAKTLTVDTGAD
                     NAAGKLTFNIDGLARAIAPLRDACHWAGE"
     gene            13269..14681
                     /gene="tssA"
                     /locus_tag="IT892_003306"
     CDS             13269..14681
                     /gene="tssA"
                     /locus_tag="IT892_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssA"
                     /protein_id="HAP3136489.1"
                     /translation="MAMDLRDPNVWISHLLENLPEEKLASALKDDNPNWEYIDGEIVK
                     LGSLAHSQLDIPELQRRGLVILASESKDFRLLAHLLRTLQHAGDPHLALRLLALYVEH
                     YWAVAAPQNMAHKKRFASQVIKRFETGIEGFSQNAATEQRDALSGELAKLAQCWQSHN
                     APELAQATDDLFALYQRAFNRAAPAPVPTPAASGSSPQTTATSESGVTQPSAPAPQIV
                     IDSHDDKAWRDTLLKVAAILCERQPDSPQGYRLRRHALWQNITSTPQAESDGRTPLAA
                     VSADMVADYHAQLGSADMALWQQVEKSVLLAPYWLDGHCLSAQTALRLGYKQVADAIR
                     DEVIRFLERLPQLTGLLFNDHTPFISEQTKQWLAASPDAKVAPVAQIGEESKAARACF
                     AEQGLEAALRYLDMLPEGDPRDQFHRQYLAAQLTEEAGLVQLAQQQYRMLFRMGLQMM
                     VADWEPSLLEQLEQKFTAEQ"
     gene            14790..18224
                     /gene="tssM"
                     /locus_tag="IT892_003307"
     CDS             14790..18224
                     /gene="tssM"
                     /locus_tag="IT892_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system membrane subunit TssM"
                     /protein_id="HAP3136490.1"
                     /translation="MLILAWIFLLVWIWWKGPTWTLYEEQWLKPLANRWLATAAWGII
                     ALMWLTVRVMKRLQQLEKMQKQQREEAVDPLSVELNAQQRYLDRWLLRLQRYLDNRRF
                     LWQLPWYMVIGPAGSGKTTLLREGFPSDIIYAPEGARGAEQRLYLTPHVGKQAVIFDI
                     DGTLCAPADADILHRRLWEHALGWLKEKRARQPLNGIILTLDLPDLLTADKRRREHLL
                     QTLRSRLQDIRQHLHCQLPVYVVLTRLDLLQGFAALFQSLNRQDRDAILGVTFTRRAH
                     ENDDWRTELNAFWQTWVDRMNLALPDLMVAQTHTRTSLFSFSRQMQGSREPLVSLLEG
                     LLDGENMNVMLRGVYLTSSLQRGQMDDIFTQSAARQYRLGNNPLASWPLVDTAPYFTR
                     SLFPQALLAEPNLATESRAWLIRSRRRLTVFSATGGVAALLLITGWHHYYNGNYQSGI
                     TVLKQAKAFMDVPPPQGEDDFGNLQLPLLNPVRDATLAYGDWGDRSRLADMGLYQGRR
                     IGPYVEQTYLQLLEQRYLPSLFNGLVKAMNAAPPESEEKLAVLRVMRMLEDKSGRNNE
                     VVKQYMAKRWSEKFHGQRDIQAQLMSHLDYALAHTDWHAERQAGDGDAISRWTPYDKP
                     VVSAQKELSKLPVYQRVYQSLKTRALGVLPADLNLRDQVGPTFDQVFTSADDNKLVVP
                     QFLTRYGLQSYFVKQRDELVELTAMDSWVLNLTRSVKYSDADRAEIQRQLTEQYISDY
                     TATWRAGMDNLNIRNFESIGQLTGALEQVISGDQPLQRALTVLRDNTQPGVFSEKLSA
                     KEREEALAEPDYQLLTRLGHEFAPENSTLAVQKDKESTMQAVYQQLTELHRYLLAIQN
                     APVPGKSALKAVQLRLDQNSSDPIFATRQMAKTLPAPLNRWVGRLTDQAWHVVMVEAV
                     HYMEVDWRDSVVKPFNEQLANNYPFNPRSAQDASLDAFERFFKPDGILDTFYQQNLKL
                     FIDNDLSLEDGDNNVIIREDIIAQLETAQKIRDIFFSKQNGLGTSFAVETVSLSGNKR
                     RSVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLIGTSGNAPRSISFSGPWAQ
                     FRLFGAGQLTGVQDGNFTVRFSVDGGAMTYRVHTDTEDNPFSGGLFSQFGLSDTLY"
     gene            18235..19587
                     /locus_tag="IT892_003308"
     CDS             18235..19587
                     /locus_tag="IT892_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001087757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136491.1"
                     /translation="MNSNVLTQTIVTGSDPRGLPEFSAIREEINKASHPSQPELNWKL
                     VESLALAIFKANGVDLHTATYYTLARTRTQGLAGFCEGAELLAAMVSHDWDKFWPQGG
                     PARTEMLDWFNSRTGNILRQQISFAESDLPLIYRTERALQLICDKLQQVELKRVPRVE
                     NLLYFMQNTRKRLEPQLKSNTENAAQTTVRTLIYAPETQASSTPEAVVPPLPGLPEMK
                     VEVRSLTENPPQASVIKQGSTVRGFIAGIACSVAVASALWWWQVYPVQQQLLQVNDTA
                     QGAATVWMASPELENYERRLQQLLDTSPVQPLETGMQMMRVADSRWPESLQQQQASTQ
                     WNEALKTRAQSSPQLRGWLQTRQDLHAFADLVMQREKEGLTLSYIKNVIWQAERGLGQ
                     ETPVESLLTQYHDARAQKQNTDALEKQINERLEGVLSRWLLLKNNVMPEAATGTTAEK
                     "
     gene            19611..20093
                     /locus_tag="IT892_003309"
     CDS             19611..20093
                     /locus_tag="IT892_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HAP3136492.1"
                     /translation="MANISYLSLSGETQGLISAGCSTLDSVGNKAQPEHKDQIMVYAL
                     MHSISRSQNVNHHELIITKPVDKSSPLLAKALSDNEKMAICEFILYRTSKAGIYQPYY
                     KINLSKARISSIDFVTPHAVLEKELEPQERIAFIYEDISWEHTLAGTNAMSKWQDRVQ
                     "
     gene            20137..21051
                     /locus_tag="IT892_003310"
     CDS             20137..21051
                     /locus_tag="IT892_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136493.1"
                     /translation="MAGLRNNNNTQNAQWADYVGDILRGAQPINQLVPQHPYLNDVPL
                     IDELRHQNTHHVIPLTLDVAKKILSPITSFDYIHFITTHPSGIKDTLAWLVNAGKLMT
                     EFDDNGKIIFNLNALKYTKASYFEILGEKYIKITTSSPWLLEKLGKYIFSSRAPQVLE
                     LAIGWRGALSESIKGVKFCIWFSVAWRTIEFIMSSERDLVNFLGDFSMDVAKAVIAGG
                     VATAIGSLASFACVSFGFPVILVGGAILLTGIVCTVVLNEIDAQCHLSEKLKYAIRDG
                     LKRQQELDKWKRENMTPFMYVLNTPPVI"
     gene            21061..>21496
                     /locus_tag="IT892_003311"
     CDS             21061..>21496
                     /locus_tag="IT892_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136494.1"
                     /translation="MRLHVKLKEFLSMFFMAILFFPAFNASLFFTGVKPLYSIIKCST
                     EMFYDWRMLILCFGFMSFSFLNIHVILLTIIKSFLIKKTKVVNFATDITIQLTLIFLL
                     IAIVIAPLIAPFVTGYVNTNYHPCGNNTGIFPGAIYIKNGMKC"
BASE COUNT         5173 a         5748 c         5826 g         4749 t
ORIGIN      
        1 ttgcacaggt tcatacaatc tatttaacgc ttgcagaata cccctcttta cgatcgataa
       61 aaagtccttt tcttatttat tttgaagcgt aaaatgcggg gtgatgaagg agtggtgatt
      121 ttattttcac cgctatcaag gcggcatttc cgatattttt tacggtacga atatgccgtg
      181 ttcatggcct gtacgagata acatgacgga tcacttttat gagcaaaaaa tttgaaggca
      241 gcgtcgcgcc tcgcgaacgt attaatatat cgtatgtccc aaaaacagat ggccagacgg
      301 ctgaagtgga acttccgctt aacatgctcg ttgtcggcga taccggaaat acgcaggaaa
      361 catcctcact ggatgaacgt caggcagttt ccgttaacaa gcacaatttc ggtgcagtga
      421 tggctgaagc agccattggc ctcaatttta ccgtccccgc cacgctgaag ggaagcacaa
      481 cggacgatga gctgaatgtg gcgctgaata tcaagtcact ggatgatttt tcaccagata
      541 gcgtggcccg gcaggttccg gaagtgaata aattgctgga actgcgtgaa gcactgactg
      601 cactgaaggg gccgatgggt aaccttccgg cattccgtac ccagctccag gcattgctgg
      661 aaaatgaaga gtcccgcgag cagttgctca aagaaatcgg ccaggtgagc aataaacaac
      721 caccactatt tcattaaaca gggttatcca ggcatgacgg cacacaaaaa tatctccggg
      781 acataccacc tctctgttgc agacattctg caggtggttt accaggtatg tttcagcccg
      841 tccgttgaaa tcaaccagga tggtgtggct gcgctgatta caacactgga tcgccgtatc
      901 agtgatctat tggatgagat tatccatttt tgtgagtttc agcagagcgc gtcgcactgg
      961 cagcgcgtac ttcactgatg gcgaaaagcc ggtttcagaa acacagctaa aacagaagga
     1021 ttttcagtat gtctttacag gaagaggaac tcgtttccag tcatgccggg cagcctgagc
     1081 aggcatcgtc gctgcttgat caaatcatgg cacagacccg tattcagccc ggttcggaag
     1141 gttatgacgt tgcccgccag ggtgtgacag cctttattgc cagcatcctg caatccactg
     1201 catctgccga accggtcaat aaactggtcg tggacagcat gattgcagat attgatgaac
     1261 gcatcagccg ccagatggat gtcatcatcc atgcgcctgc ctttcagcag gtcgagtcgt
     1321 tctggcgctc actgaaaacc atggtggatc gcgttgattt ccgtgaaaac atcaaggtca
     1381 acgtgcttca tgtcaccaag caggaacttc tggaagactt tgagtttgcg ccagaaatta
     1441 ttcagtccgg attttataag cacgtttatt cgtccggttt cggacagttt ggcggtgaac
     1501 ccatcgctgc cgtgctgggc gcttatgagt tcaaaaatac cgcgcctgac atgaaactgc
     1561 tgcaatacgt cagtgcagtg ggcgcaatgg cgcacgcacc gttcctgtcc tccgtttccc
     1621 cggagtttat ggggctgaac tcgtggaccg aactgcctaa tatcaaagat ctttatgcca
     1681 tctttgaagg tccggcctac accaaatggc gcgccctgcg tgactcggaa gattcgcgct
     1741 atttagggct tacggcaccc cgcttcctgc ttcgccagcc ctattcacca acagataacc
     1801 ctgttaagaa ctttaactat tacgaagatg tcagccagaa ccacgaagat tatctgtggg
     1861 gtaatacggc ctggatgctg gcatgcaata tcgcagacag ttttgccaaa taccgctggt
     1921 gtccaaacat tatcggtccg caaagcggcg gcgcagtgaa agatctgccg gtgcatctgt
     1981 tcgaaacgat ggggcagatt caggccaaaa tcccaaccga ggtgctggtc accgatcgcc
     2041 gcgaatttga actggctgaa gagggtttta tcacccttac catgcgtaaa gactctgata
     2101 atgcagcctt tttctctgca aactcggtac aaaaaccgaa gcactttccg ggaaaagatg
     2161 cagaaaccaa ctataagctg ggtacgcagc ttccttatct cttcatcatc aatcggttag
     2221 cgcactacat caaggtgttg cagcgtgaac aactggggtc atggaaagaa aggagcgact
     2281 tagaaagaga gcttaatacc tggatccgtc agtatgttgc cgaccaggaa aacccgcctg
     2341 cagacgtgcg cagccgcaaa cctctgcgcg ctgccaaagt tgaggttatg gatgtagaag
     2401 gcgaacccgg ctggtaccag gttgcgctaa gcgtgagacc tcattttaaa tttatggggg
     2461 caaattttga gctttccctg gttggccggt tagacaggga gtaacacacc atgataccgg
     2521 atcgggaaag aaccacaggt tctctttttg agcgtatgga agcctcttcg gccagaaacc
     2581 ggcagggagg cagtattcat tcgctcaggc aatccattcg ccagaaccta cgaaacattc
     2641 ttaatacccg gtccggtagt tgccggggtg cgcctgagct gggcattgat gaaccggaag
     2701 gggctgaaaa cttccgcgaa tccatgagtc gggccatcga gcaatgtata gaacgctatg
     2761 aaccccggat ctcacacgct gaagtgcagg tagtggtttc atccgcctcc agcccgctgg
     2821 atatgacgtt tcatattaca gcctgggtga catttaacga aacgcatgag gtgcttgaat
     2881 ttgatatggc accgaatggc agccagcatt accgggtgga ctgacaaatg gaatttgaag
     2941 aacgctattt ccgggaagaa ctcgattacc tgcgccagct tagcaagctg ctggcaacgg
     3001 aaaaacccca tctggcccgc ttcctggccg aaaaagatgc ggatccggat attgaacgcc
     3061 tgctggaagg ggtggctttt cttaccggca atctccgcca gaaaattgag gatgaattcc
     3121 cagaactgac gcacgggctt attaagatgc tatggcctaa ttacctgcgt ccggttccgg
     3181 caatgaccct tattgaatat acgccggata tggataagtc ttctgtaccg gtgttaatcc
     3241 cccgtaatga gcagtttaca accaacgccg gggaaatcag agttgatgaa gtgctgccct
     3301 ctgatgctaa aaaggaggag ccgcctccct gtaccttcac cctctgccgg gatatctggc
     3361 tgctgcccgt tcgcctggag cagattgaaa accgcagtac gacccgtaat ggtgttatca
     3421 acatcacctt ttcggtcgca ccgggaacgg acttccgcac gctggatctg aacaaacttc
     3481 gcttctggct cggcaatgac gacaactata cccgtgacca gctttattta tggttctgcg
     3541 aatacttgca gggtgccgac ctgactgtgg gtgaacagca tcttcgcctg cctgagttta
     3601 tgctaaaagc tgtcggtttt gagccgcagg atgccatgct gccctggccg aaaaacgtcc
     3661 acagcggcta ccggatcctt caggagtatt tctgttaccc cgatgcgttt ctcttttttg
     3721 atctttgtgg ttgtccggct ttgcctgacg gattgcaggc ggaattcttt accctgcaac
     3781 tgcgtttttc gcgccctttg cccgtggaca tccggctgcg ccgcgattcc ctgcgcctgt
     3841 attgcgcacc tgccattaat ttatttatcc accatgcaga agccatcacg ctggacaacc
     3901 ggcgggcaga ctatccgctg gttcccagcc gccattaccc acaacattac gatgtatttt
     3961 ccgttaacag tgtggtgagc caggtccagg atatgttcag gaaaaaagat ctggggcgtc
     4021 ctgtttcgac gcaggccgcg cgccagtggc cagcctttga aagtttcagc catcagatgg
     4081 aatacagccg gaagcgggaa gtggtgtact ggcatcaccg gaccaaaaca tccctgttcc
     4141 atcgcggctt tgatcatacc cttgccttta tacatgctga tggcagttat ccgtcagacg
     4201 aatctctgct cagtaatgaa gtggtttcgg tatcgctgac ctgtaccaac cgtgagcttc
     4261 cgtcacaaat tcgttccggc gatatcaccg gcacaaccgg taaaaatgca gctgttgctt
     4321 catttcgcaa cattacccgc ccgacgcaac cactctggcc ggtcattgat ggcagcctgc
     4381 actggtccct actctccgcc atgaacctga attatctgtc attactggat acggacgcgc
     4441 tgaagcaggt catcgccaac tttgatcgcc acgcaatcca tcatccgcag acggcacggc
     4501 tgtcacaaca aaagctggat gccattgagc gtctggagac ccgccccgtt gatcgcctgt
     4561 ttacgggtat tcccgtccgg ggactggcct ccacgctgta tctgcacccg gagccgtttg
     4621 tctgtgaagg ggaaatgtat ctgctcggta cggtgctttc gcattttctg tcgctgtacg
     4681 ccagcgttaa ctcattccac atgctgaccg ttgtgaacac agaaagccag gagacatgga
     4741 aatggacgga aagaatcggg cagcatcctc ttatctgagt ccgggaaatc ccccggcaga
     4801 taaagagcag aatgatccgc tggcacaggt tttccataat gcctgctctt acaatttttt
     4861 tgcgatggcg gagctgttgc accgcctggc aaagggtgaa aaggggacgc cagaattatc
     4921 cctgcgtgac gatccggcac aggaaaccct gcgtttcagc gccgatgcca gccttgcctt
     4981 cccgtgcagt gatatcagtg cgctgaaacg ggatacatca ggggcattca ggatgaccac
     5041 cacctttatg gggttacagg ggagccagtc gcctctcccc ggttattacc tcgatcacct
     5101 ggcctggaaa gcggtacatg aacaaagtcc ggtaggtgat tttctggata tgttcagcca
     5161 ccgcctgacc cagtttgtct ggcatatctg gcgtaagtac cgctatcaca tcagttttcg
     5221 taacggcggt gtggatgcgt tctcgcagcg catgtactcc cttgtcgggc tgggccaccg
     5281 ccagcttcgc gataagctgg cgattaatca cagcaaaatg ctggcgtatt ccgggatcct
     5341 ggcaaatccg ggacgatccc cggaaataat ctgtggcctg gtgtcccact gctttgattt
     5401 gtcagaagtg acgctgcaaa actggcaacg tcgcaaggtg gatattgaac cggatcagca
     5461 aaatagtctg gggagctatt ctcttaaaaa tggcgaaaaa ctggcgggaa gatcggtact
     5521 gggcaacttt gttctgggta cacgagtgcc cgatctcagc ggaaaattcc agctcagtat
     5581 taccagcctg acccgaaaac agttcctctc ttttctgccg tccggcgaaa acttcctgcc
     5641 actgacgatg ttcgtgtcct tcatcctgcg cgatcagctt gcctgggact tacatctggg
     5701 gctggcgccg gagcaggtgg gcgcaatgcg cctgggtgat aacaaaagtg cgctgctggg
     5761 ctggaccagc ttcctcggca caccggaaga acgaccctca gtcaccatca gggtacggtc
     5821 gtaaattatg ataatcacgg agcagaatat gccggaagag aaactacaga cgctttcatt
     5881 gcaggtcatt aacggcagtg agctggaaag cgggcgggcg gcgcgctgtc tattcacaca
     5941 gcagggaaat gtcggccatg gccccgaatg ccactggtcg gtacaggatc gtcagcagag
     6001 cattccggcc caggctttta ccgttatcct gcacgatggc acattttgtc tgcgcccgca
     6061 gacggcacaa ctgtggctga atcaggcaaa agtcacagca acatcagacc taatacagtt
     6121 gcgccagggc gatgagatcc agatcggacg gctgatggtg agggttcatc tgaaccgggg
     6181 agatattccc cattacgatg aggaaatggc cactcccgaa accatcgtta ccaatcgcga
     6241 tatgctcacg gataccctgc tatcaacgga gggtgcgcca cactatccgg gaatgactca
     6301 ccggcaccag cttgcagaca gcgtggtaaa cggtttttct gccgatccac tccaggcact
     6361 tcagtccgaa agcctgatta ccacgggcga tccgctttca ggcattgcgg ctgtccggcc
     6421 atcggcaccg ctgtccgatc cggcaagtaa tggggggatc aatactccgt ttatggatct
     6481 gccgcccatt tatgccagcc ccggcgatcg taatgacgac gtctctgcgg cagaaatggc
     6541 gcaacgccac cttgcggtca cccccttact gcgcggtctt ggcggctcgc ttaccatgag
     6601 caattccgac gatgcggatg attttctgga ggaggccgga cgaacgttac aggccgcaat
     6661 aaaaggtctg ctcgatttgc agcagcagcg taacagcctc tcagacaaac atttgcgccc
     6721 gctggaagat aacccgctgc gcctgaacat ggattacgcc accgcgctcg acgtaatgtt
     6781 tgccgaaggt aaaagcccgg tacatctggc ggctcccgcc gccgtcagtg aaagcctgcg
     6841 caatgtccgc caccacgaag aagctaaccg ggcagcgatt gtggagtcgc ttcgtgtcct
     6901 gctggatgct ttctcaccac aaaatctgct gcgccgcttt gtgcagtacc gccgcagcca
     6961 tgaactgcgc cagccgctgg atgatgccgg agcatggcaa atgtacagcc attattacga
     7021 agaactggcc tccgatcgcc agcaggggtt tgagatgctg tttaacgagg tctacgccca
     7081 ggtctatgac cgggtgcttc gtgaaaaaca gcgggagccg gaagcatgaa caggaaggcg
     7141 tttctggcct gcgtgctgat gtgcgtcata ttaaccggct gcgaaacggc gaaaaaaatc
     7201 agcgaggtga tcaaaaaccc ggatatccag gtcgggagcc tgaaggagca accttcggaa
     7261 ataaccgtca ccctgctgac tgaaccggac accaatacca atgcggaggg tgaatcagcc
     7321 gccgtggatg tgcaactggt gtacctgact gacgactcaa aattgctggc agccgactat
     7381 gaccagatag ccagtacgcc gctaccggat gtgttgggta aaaactatat cgaccaccag
     7441 gatttcaacc tgttgccgga caccatcaaa accctgccgc cggtaaagct ggatgagaaa
     7501 acgcagttta ttggtgtcgt ggcctatttc tccgatgacc aggccactga atggaaacaa
     7561 atcgagacgg tggaaggaac cggccaccat taccgcctgc tggtgcatgt acgtcaaagc
     7621 agcatcgaaa tgaaaaaaga ggatgaataa ttatggcaac cacccgcaac aaggtgatgt
     7681 ggcaggaagg gatgctgatg cgcccacacc atttccagca acagcagcgt tacaacgact
     7741 acctggataa ccagcgtttc cgggccatga atgatttatc ctggggattt accgaactca
     7801 ccctcaacaa tgaactgctg gcgcagggta agatcatgat tgacagcgcg tcaggcacac
     7861 tgcccgacgg caccgtcttt tctatccccg accaggacgc actgcccgat ccgctgcacc
     7921 cgcaaaattt tccggacgaa agaagccgca atatctacct cgctctgccg gtcgccagtg
     7981 atgtgagaaa tgaaatcagc gacggacggc gaatcgggcg ttaccggctg aattatgccg
     8041 atgtccggga tttgcattca gaagaaggtg acgcgcgaac attgacgctg ggtcaactga
     8101 cgccgcgcat tatgagcggt gcagaagata tgagcgccta tattacgctc ccgctttgcc
     8161 gtatcagcaa tcgccatgcc gatggctccc tgacgttgga tgacgatttt atcccctcct
     8221 gccagaatat tcaggtcagt aagaaactgc gtgtttatct caaagaggta cagggggcca
     8281 ttggcggacg ggcaagcgat ctggcaaacc gtattggctc tccggcgcag agcggcatcg
     8341 cggatgtggc ggaatttatg atgttgcagt tacttaaccg taaccagacc cggtttaccc
     8401 atcgcgcccg ccgatcccag ctccacccgg aagatttcta ccttgatctt gctgggttgc
     8461 tgggtgaact gatgaccttt accgagccgt cgcgcctgcc ctgcccgctt gatgtgtatg
     8521 atcatcatga tctgaccaaa acatttaaaa cactgttacc ggaagtcaaa cgggcgctgc
     8581 ataccgtact gtcgccaaga gcggtcaatc tgccgctgca tctgcgtgac ggtatctggc
     8641 aggccgatat ccatgacaca gaactgctgc aatctgccac ctttgtgctg gccgtggcgg
     8701 caaacgtgcc ggtcgatcag atccagcgtc agtttatcca gcagtcgaaa atttcctcgc
     8761 cggaaaaaat ccgcaatatg gtcagtgtgc agatccccgg tattccattg cgtgccctta
     8821 tggtggctcc ccgccagctt ccttaccatt ccgggttcag ctatttcgaa ctcgacaaga
     8881 gtggccaggc ctggacagaa atggctgccg ccggggccgt tgcactgcat gtttccggca
     8941 gtttcccgga tctgaacatg caactgtggg cgataagagg gtaagacgat ggatgagggg
     9001 tcactgtctc tgccaccatt taccggacac gacgaaaaaa gccagcgcaa ctaccatctc
     9061 gcgcttcgtg gcaacagcct gaatccgatg atcgacgcgg ccacgccgct actcggtatg
     9121 gtaatgcgcc tttcaaccat gaacagccag acgatgccgg agcatctttt tgctcaggtg
     9181 gtgacagatg ttcaggccgt ggagcaactg cttcaggagc agggctacga accgggcgtg
     9241 attatctcgt ttcgctacat cctctgcacg tttattgatg aagcggcgct cggtaacggc
     9301 tggtcaaaca agaacgagtg gatcaagcag tcattgctgg tccatttcca caacgaagcc
     9361 tggggtggcg agaaagtttt catcctgctg gagcgcctga tccgtgaacc caaacgttac
     9421 caggatctgc tggaatttct ctggatctgt ttttctctgg gatttcgcgg gcgctacaaa
     9481 gtggcagcac aggatcaggg ggaatttgag cagatctacc gccgtctgta ccacgttctg
     9541 cataaactgc gcggcgatgc ccctttcccg ctgttacacc aggacaaaaa aacccagggc
     9601 gggcgttatc agctcatcag tcgcctgact gttaaacata ttttttgtgg tggcgttgtc
     9661 gtgctggcgt tgttttacct gttctatctg ttgcggctgg acagccagac gcaggacatc
     9721 ctgcaccagc taaacaaatt acttcgataa ggacgtttat gatccagatt gatcttcccc
     9781 cgctggtaaa acggctgaac ctgttctccc gccaggcgct ggagatggcc gcctctgaat
     9841 gtatgagtca gcaggcagcg gaaattaccg tcagccatgt gctcattcag atgctcgcca
     9901 tgccacgcag tgacctgcgg gttattaccc gccagggcga tattggcatg gaagagttgc
     9961 gccaggcgct gacggtagag aactacacaa ccgcccgttc tgcggacagc tacccggcgt
    10021 tttccccgat gctggttgag tggcttaaag agggctggct gctggcgtcg gctgagatgc
    10081 agcacagcga actgcgcggc ggcgtgttgc tgctggccct gctgcattcg ccgctgcgtt
    10141 atataccgcc tgctgccgcc cggctgttga ccggcattaa ccgtgaccgt ctgcaacagg
    10201 actttgtgca gtggacacag gagtcggcgg aatcagtcgt gccggatgca gacggtaaag
    10261 gcgcaggcac aatgacggac gcctctgaca ccctgcttgc ccgctatgcc aaaaacatga
    10321 ccgcagacgc ccgtaacggc aggcttgacc cggtactgtg ccgcgaccac gaaatcgacc
    10381 tgatgatcga cattctctgc cgccgccgta aaaacaaccc ggtggtggtg ggcgaagcgg
    10441 gcgtgggcaa aagcgcactg attgaagggc tggcgctgcg catcgtggca ggccaggtgc
    10501 cggacaagct gaaaaacacc gatatcatga cccttgactt gggcgcattg caggccgggg
    10561 cgtcggtgaa gggtgaattc gaaaaacgtt tcaaagggct gatggcggag gtcatttcct
    10621 ccccggtgcc ggtcattctg tttatcgacg aagcacatac cctgattggc gcgggcaacc
    10681 agcagggcgg gctggatatc tccaacctgc tcaaaccggc gctggcgcgc ggcgagctga
    10741 aaaccatcgc cgccaccacc tggagcgagt acaaaaaata cttcgaaaaa gatgccgccc
    10801 tgtcgcgccg cttccagttg gtgaaggtca gcgaacccaa cgctgccgaa gccaccatta
    10861 ttctgcgcgg tctgtcggcg gtctatgaac agtctcacgg cgtgctgatt gatgatgacg
    10921 ccttgcaggc cgctgcgaca ttaagcgagc gttatctctc cgggcgtcag ttaccggaca
    10981 aagcgattga tgtgctggat accgcctgcg cccgtgtggc catcaacctg tcgtcgccgc
    11041 cgaagcaaat ctcggcgctg accactctga gccaccagca ggaggcggaa attcgccagc
    11101 ttgagcgcga gcttcgcatc ggactgcgta ccgacacatc acggatgaca gaggtgctgg
    11161 tgcagtatga tgaaacgctg acggcgctgg atgaactgga agcggcctgg caccagcagc
    11221 agacgctggt ccgggagatt atcgcgctgc gccagcagtt actgggcgtg gcagaggacg
    11281 atgcggcgcc gttgccggac gcagataccg tggaggatac gcagccagag tcagagtcag
    11341 aacaggataa taccggtgcc gtaccggctg atgaggccga cagagaacaa ccggaagaga
    11401 ccgctgaaac agtttccccg gtacagcggc tggcccagct cactgccgaa ctggacgccc
    11461 tgcataacga ccggttgctg gtctccccgc acgtcgataa aaaacagatt gcggcggtga
    11521 ttgccgaatg gaccggcgtg ccgctcaacc gcctgtcgca gaatgaaatg tcggtcatca
    11581 ccgacctgac gaaatggctg ggtgacacca tcaaaggcca ggacctggcg attgccagcc
    11641 tgcataagca tctactgacc gcacgcgccg acctgcgtcg tccgggacgc ccgctcggtg
    11701 cgttcctgct ggctggcccc agcggtgtgg gtaaaaccga aaccgtcctg caactggcag
    11761 agctgctcta cggcggtcgc cagtacctga ccaccatcaa tatgtccgaa ttccaggaga
    11821 aacacaccgt ctcgcggctg attggttcgc ctccgggcta cgttggctac ggtgaaggcg
    11881 gcgtactgac cgaagcgatt cgtcagaaac cctactcggt agtactgctc gatgaagtgg
    11941 aaaaagcgca cccggatgtg ctcaacctgt tctaccaggc gttcgataag ggcgaaatgg
    12001 cagacggtga aggccgcctg attgactgca aaaatatcgt cttcttcctg acgtccaacc
    12061 tcggctacca ggtaatagtc gagcatgccg atgacccgga aaccatgcag gaagtactgt
    12121 atccggtgct ggccgacttc ttcaaacctg ccctgctggc gcgtatggaa gtggtgccgt
    12181 atctgccgct gtcgaaagag acgctcgcca ccattatcgc cggaaaactg gcccgtctgg
    12241 ataacgtgct gcgcagtcgc tttggtgcag aagtggtcat tgaaccagaa gtgacggacg
    12301 aaatcatgag ccgcgtcacc cgcgcggaaa acggcgcgag gatgctggaa tcggtcatcg
    12361 atggcgacat gctaccgccg ctctcgctgc tgctgttgca gaaaatggcg gctaacacgg
    12421 cgattgcccg gattcggttg tcggcagtgg acggcgcatt tacggcagac gtggaagatg
    12481 ctcagaacga cgagtccgtc acaaaggatg aaacggtttt atgagcaggt tgcgcgtttt
    12541 ccggcagaca ggatggttta tcgcgggcct gatgacgggc ttacccgcca ctgccgcgcc
    12601 cgcagaagca tcgtcaatgg ccggtgtggc ggtcgccgtc gccaccacga ccccgccgga
    12661 tgcgacagcc acgttacagg ccatacagtc ctgtcggcgg gagtccgcgg cgctggagcg
    12721 gcttgactgc tatgaccgcc tgctggcacc gctgtccccg tcagggtttg acggggcgct
    12781 ggtcaaagcc ggttttgtgg gcgaggcctg gacccgcgcc acagagcagg aaaaacgccg
    12841 cgagggcaac accacagaac tgctggtgac gcaggtgccg ggggagcgcc cgacggtggt
    12901 gataaccacc ccggctatcg gtcatgttcc gccacgcccg gtgctgatgt tcagttgcgt
    12961 ggacaatatc acccggatgc aggtggcgct gatgcaccct ctggatgtcc atgatatcgc
    13021 cgtcactctg aatgccgaca accgggcatt gcgcagccac tggtttgtgc gcgagaacgg
    13081 caccctgctg gagtccagcc gggggttatc cgggattgat gaaattaagc aactgttcgg
    13141 cgcaaaaacg ctgacggtgg ataccggcgc agacaatgcc gccggaaagc tgacctttaa
    13201 cattgacggg ctggcaaggg cgattgctcc cctgcgcgat gcctgccact gggcgggaga
    13261 ataaaaatat ggcaatggac ttacgcgatc cgaatgtctg gatatcgcac ctgctggaaa
    13321 acctgccgga agagaaactg gcatcggcgc tgaaagatga caacccgaac tgggagtata
    13381 tcgacggcga aatcgtcaag ctgggatcgc tggcccacag tcaactggat atcccggaac
    13441 tccagcgccg ggggctggtc attctggctt cggagagtaa ggattttcgt ctgctggcgc
    13501 atctgctgag aaccctgcaa cacgccggtg atcctcatct cgcattgcgc ctgctggcgc
    13561 tgtatgtgga gcattactgg gcggtggctg cgccgcagaa tatggcgcat aaaaaacgct
    13621 ttgccagcca ggtcattaaa cgctttgaaa caggtattga aggtttttca cagaacgccg
    13681 ccacagagca gcgcgatgcg ctgtcagggg aactggcaaa actggcgcaa tgctggcagt
    13741 cacataacgc cccggaactg gcacaggcta ctgatgatct ttttgccctg taccagcgtg
    13801 cgtttaatcg tgcggcaccg gctcctgtcc ccactccggc ggcctccggt agttcaccac
    13861 agaccaccgc cacgtctgaa agcggcgtga cgcaacccag tgctccggct ccccaaatcg
    13921 tcatcgacag tcacgacgac aaagcctggc gcgacacgct gttaaaagtg gcggccattt
    13981 tatgtgaacg ccagccggat tcaccgcagg gctaccgtct gcgccgccat gcgctttggc
    14041 agaacatcac cagtacgccc caggcggaaa gcgatggccg tactccactg gctgcggtct
    14101 ccgccgatat ggtggcagat taccatgctc agctcggtag tgccgatatg gcgctgtggc
    14161 agcaggtgga gaaaagcgta ctgctggctc cttactggct ggatggtcac tgcctttctg
    14221 cacagacggc gctgcgtctg ggttacaaac aggtggcaga cgccatccgc gatgaggtca
    14281 tccgcttcct tgagcgtctg ccccagctta ccgggttgct gtttaatgac cacacaccgt
    14341 ttatcagtga gcagacgaaa caatggctgg cagcttcgcc cgacgccaaa gttgcaccgg
    14401 ttgcgcaaat cggtgaggaa tcgaaggcag ccagagcctg ttttgctgag cagggtctgg
    14461 aggcggcgct gcgatatctg gacatgctac ccgaaggcga tccccgcgat cagtttcacc
    14521 gccagtacct tgccgcacag ttgacggaag aggcggggct ggtacagctt gcgcagcagc
    14581 agtaccggat gttgttcagg atgggattgc agatgatggt ggcagactgg gagccgtccc
    14641 tgcttgagca gctagaacaa aaattcacgg cagaacaata aaagagaaca ggagtttttg
    14701 tgttcagatt accaacaccc cgactactca gcggactcaa atcagccctg cgaccggcga
    14761 tgccccggtt taaagtctct gctttctggc tgctgatact ggcgtggatt tttctgctgg
    14821 tgtggatctg gtggaaaggc ccgacgtgga cgctgtatga agaacagtgg ctcaaaccac
    14881 tggcgaaccg ctggctggca acggcggcgt gggggattat tgccctgatg tggcttaccg
    14941 tccgggtgat gaagcgcctg caacagcttg aaaaaatgca aaagcaacag cgcgaggaag
    15001 ccgttgatcc gctcagcgtg gaactgaacg cccagcagcg ttatcttgac cgctggctgc
    15061 tgcgcctgca acgctatctc gacaaccgcc gtttcctgtg gcagttgccg tggtatatgg
    15121 tcatcggccc ggcgggcagt ggcaaaacga cactgctgcg cgaggggttt ccgtccgaca
    15181 ttatttatgc cccggagggc gcgcgcggcg cagaacaacg cctgtacctt acgccccatg
    15241 tcggtaaaca ggcggtgatc tttgatatcg acggcacact ctgcgctccc gctgatgcgg
    15301 atatcctgca tcgccgtctg tgggaacatg ccctcggctg gctgaaagaa aagcgcgcgc
    15361 gccagccgct gaacgggatt attctgacac tcgatttacc cgatctgctt accgcagaca
    15421 aacgccgccg cgagcatctg ttacagacgc tgcgcagccg cttgcaggat atacgccagc
    15481 atcttcactg ccagttaccg gtttacgtgg tactcacccg gcttgattta ttgcagggtt
    15541 ttgccgccct gttccagtca ctgaacagac aggatcgcga tgcgattctg ggcgtcacgt
    15601 tcacccgccg cgcccatgaa aatgatgact ggcgaacaga gttgaatgct ttctggcaga
    15661 catgggtgga tcgaatgaat ctggcgttgc cggatctgat ggtcgctcag actcacaccc
    15721 gcacgtcttt attcagtttt tcccgccaga tgcagggaag ccgtgaaccg ctggtgtcac
    15781 tgcttgaggg tctgcttgat ggcgaaaata tgaacgtgat gctgcgtggt gtctatctca
    15841 cctcttcgct tcagcgtggg cagatggatg atatattcac ccagtctgcc gcccgccagt
    15901 accggctggg caataaccca ctggcgtcct ggcccctggt ggacaccgcg ccttatttca
    15961 cccgcagcct gttcccgcag gcattactcg cagagcctaa tctggcaaca gagagccgcg
    16021 cctggctgat acgttcccgt cgccgcctga cagttttctc tgccacaggc ggcgtggcag
    16081 cacttctgct catcaccggc tggcatcact attacaacgg taactatcag tccggcatca
    16141 ccgtgcttaa gcaggccaaa gcctttatgg acgtgccgcc tccgcagggg gaagatgact
    16201 ttggcaacct gcaactgccg cttctgaacc cggtacgcga tgccacactg gcctatggcg
    16261 actggggcga ccgcagccgt ctggccgata tgggactgta ccagggacga cgtatcgggc
    16321 cttatgtgga acagacctat ctgcaactgc tggagcaacg ttacctgccc tcgctgttta
    16381 acgggctggt caaagcgatg aacgccgcgc cgccggagag tgaagaaaaa ctcgcggtgc
    16441 tgcgcgtaat gcgaatgctg gaggacaaaa gcggacgtaa caatgaggtg gtgaagcagt
    16501 atatggcaaa acgctggagc gaaaaattcc acggccagcg cgatatccag gcacaactga
    16561 tgtcccatct tgactacgcg ctggctcata ctgactggca tgcagagcgt caggcgggcg
    16621 acggtgacgc catcagccgc tggacgccat atgacaagcc cgtggtatca gcacagaaag
    16681 aactgagcaa actgcctgtc taccagcggg tttaccagag cctgaaaacg cgggcgctgg
    16741 gcgttcttcc tgccgacctc aatctgcgtg accaggtagg gccaaccttt gaccaggtgt
    16801 ttacatctgc cgatgacaac aaactggttg ttccacagtt tcttacccgt tacggcctgc
    16861 aaagctattt tgtaaaacag cgcgatgaac tggttgaact gacggcgatg gattcctggg
    16921 tacttaacct tacccgcagc gtgaaataca gtgacgccga ccgcgcggaa atccagcgcc
    16981 agttgaccga gcagtatatc agcgactaca ccgccacctg gcgggccggg atggacaatc
    17041 tgaatatccg caattttgag tccatcggac aactgaccgg ggcgctggag caggttatca
    17101 gcggcgacca gcctttgcag cgggcgctga ccgtcctgcg tgacaacaca cagccaggcg
    17161 tcttttctga aaaactctct gccaaagaac gggaggaagc cctggcagag ccggattacc
    17221 agttactcac ccgcctcggg catgaattcg ccccggaaaa cagtaccctg gcagtacaga
    17281 aagacaaaga aagcacgatg caggccgtgt atcagcaact caccgagttg caccgctacc
    17341 tgctggcaat ccagaacgcg cctgtaccag ggaaatcggc gctgaaagcc gtgcagttac
    17401 ggcttgatca gaacagcagc gatccgatat tcgccacccg ccagatggca aaaacgctgc
    17461 ctgctccgct caaccgctgg gttggcagac tgactgacca ggcctggcat gtggtgatgg
    17521 tggaggctgt tcattatatg gaagtggact ggcgcgacag cgtggtgaaa ccgtttaacg
    17581 agcaactggc aaataactat ccgtttaatc cgcgttctgc acaggatgcc tcactggatg
    17641 ccttcgaacg cttctttaaa ccggatggca tactggatac cttctaccag cagaacctga
    17701 agctgtttat cgataatgac ctgagtctgg aggatggcga taacaacgtc attattcgcg
    17761 aagatattat tgcgcaactg gaaactgcgc agaaaatccg tgacatcttc ttcagcaaac
    17821 agaacggtct gggaacatcc tttgccgtgg aaacggtatc gctttcaggc aataaacgcc
    17881 gcagtgtact gaaccttgac ggtcagttag tcgattacag ccagggccgt aactataccg
    17941 cccatctggt ctggcctaac aacatgcgcg aaggcaacga aagtaagctg acgctcatcg
    18001 gcaccagcgg caacgcgccg cgcagtatca gcttcagcgg gccgtgggcg cagttccgcc
    18061 tgttcggggc cggacaactg accggagtac aggatggcaa ctttaccgtg cgctttagcg
    18121 tggacggtgg cgcgatgacc taccgtgtgc ataccgacac ggaagataac ccgttcagcg
    18181 gtgggttgtt cagccagttt ggtctgtcag acacactgta ctgaggaggc agggatgaat
    18241 agtaacgtac tgacacaaac tatcgttacc ggcagtgacc cgcgcgggct gccggaattc
    18301 agcgccatcc gcgaggaaat aaacaaagcc agccacccgt cacagcctga gctgaactgg
    18361 aaactggtgg agtcgctggc gctggcgatt tttaaagcca acggtgtgga tttacacacc
    18421 gccacctact atacgcttgc ccggacacgg acacagggac tggcgggatt ctgcgaaggt
    18481 gcggaactgc tggcggcaat ggtaagccac gactgggata agttctggcc gcagggcggc
    18541 ccggcgcgta ctgaaatgct ggactggttt aactcccgaa ccggcaatat tctgcgtcag
    18601 caaatctcct ttgcggaatc cgacctacca ctgatctacc gcacagagcg ggcattgcag
    18661 cttatctgcg ataagctcca gcaggtggaa ctgaagcgcg ttccgcgcgt ggagaatctg
    18721 ctctatttta tgcagaacac gcgtaaacgg cttgaacccc agctgaagag taacactgag
    18781 aacgccgcac agaccacggt cagaacgctg atttatgccc cggaaacaca ggcatcttcc
    18841 acaccagaag cggtagtgcc tcccctgccc ggcctgcctg agatgaaagt ggaagtgcgc
    18901 agtctgacag agaatccccc acaggccagt gtgataaagc aaggcagtac ggtaagaggg
    18961 tttatcgcag ggatcgcctg ttcagtggct gtcgcctcag cattgtggtg gtggcaggtc
    19021 tatccggtgc agcagcaact gttacaggtt aacgacaccg ctcagggcgc agcaacggtg
    19081 tggatggcct cacctgaact cgaaaactat gagcgcaggc tgcaacaact tcttgatacc
    19141 tccccggtac agccgctgga aaccgggatg cagatgatgc gtgttgccga cagtcgctgg
    19201 ccggaaagcc tgcaacagca acaggcctcg acacaatgga atgaggcact caaaacccgc
    19261 gcacagagta gcccgcagtt gcgtggctgg ttgcagaccc gccaggactt acatgctttt
    19321 gcagatctag tgatgcagcg cgagaaagag ggactaaccc tttcctatat caaaaatgtc
    19381 atctggcagg cggagcgggg actggggcag gaaacacccg ttgagtctct gttgacgcag
    19441 taccatgatg cccgtgcgca gaagcagaat acagatgcgc tggaaaaaca aattaatgag
    19501 cgactcgaag gcgtgttaag ccgctggctg ctgctgaaga ataacgtcat gccagaggcg
    19561 gcaaccggta ccacggccga aaaataatta tttaattaaa ggagattatc atggcaaata
    19621 taagttattt atctttgagt ggagagacac aagggctaat ttcagcaggt tgctcaacgc
    19681 ttgattctgt cggaaacaaa gcgcagccag aacataaaga tcagatcatg gtttatgcgt
    19741 taatgcattc catctcaaga agtcaaaatg tcaatcatca tgaattaatt atcaccaaac
    19801 cggttgataa atcctcacca ttgctggcaa aagcacttag tgacaatgaa aaaatggcaa
    19861 tatgtgaatt tatactctac cgaaccagta aagcgggtat ttaccagcct tattataaaa
    19921 taaatctgtc aaaagcccga atatcaagta ttgattttgt cacaccgcat gctgtcctgg
    19981 aaaaagaact ggaaccacag gagagaattg cctttattta tgaagatatt tcctgggagc
    20041 atacgttagc cggtacgaat gcaatgagta aatggcagga tcgtgtacag taacttactg
    20101 taataacata ataaattact attgcggaga gataaaatgg ctggtttaag gaataacaac
    20161 aacacacaga atgcacagtg ggctgattat gtgggtgaca ttcttcgggg ggctcagccg
    20221 ataaaccagc tagtacctca gcacccttat cttaacgacg tcccactcat tgatgagtta
    20281 aggcatcaga acactcatca tgttattccc ttgacacttg atgttgcaaa aaaaatactc
    20341 agcccaataa catcatttga ttacattcat tttatcacta cacatccttc aggtataaaa
    20401 gatacactcg cctggttagt taacgcgggt aaattaatga ctgagtttga tgacaatggg
    20461 aaaattatat ttaaccttaa tgccttaaag tatacaaaag caagttactt tgaaatactt
    20521 ggagagaaat atataaaaat cacaacatcc agcccctggc ttttagaaaa gctcggtaaa
    20581 tatattttct cttcacgagc gcctcaagtt ctggaactcg ctattggctg gcgaggagct
    20641 ttatctgaat caataaaagg agttaagttc tgtatctggt tttcagtagc ctggagaacc
    20701 atagaattta ttatgagttc agagcgagat ctggttaatt ttcttggcga tttttcaatg
    20761 gatgtggcca aagcagttat agccggtggt gttgcaaccg ctattggaag tctggcttct
    20821 tttgcctgtg ttagctttgg ctttccagta attcttgtcg gaggagcaat tttactgaca
    20881 gggatagtgt gtacagttgt tttaaatgaa atcgatgctc aatgccattt atcagaaaaa
    20941 ttaaaatatg caattagaga tggactaaaa cggcaacagg aacttgataa atggaaaagg
    21001 gaaaacatga ctccatttat gtatgttctt aacactccac ccgtgatatg aggattaacc
    21061 atgcgtttac atgttaaatt aaaagagttt ctttcgatgt tttttatggc catattattt
    21121 ttccctgcat tcaatgcttc tttgtttttt accggagtta aacctctata ttcaataata
    21181 aaatgctcca cggaaatgtt ttatgattgg agaatgttga ttctgtgctt cggtttcatg
    21241 tcgttttcct ttttaaatat tcatgtaatt ttacttacga taataaaatc attcttaatc
    21301 aaaaaaacga aggtagtcaa tttcgccaca gacataacaa tacagctaac tcttatattt
    21361 ttactaatag ctatcgtaat agcaccttta atagctcctt ttgtcacagg atatgtcaat
    21421 actaattatc acccctgcgg taataatacg ggaattttcc caggagcaat ctatattaaa
    21481 aatggcatga aatgta
//
LOCUS       DACAOP010000083        21401 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.083, whole genome shotgun sequence.
ACCESSION   DACAOP010000083 DACAOP010000000
VERSION     DACAOP010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21401
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.083"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..306)
                     /locus_tag="IT892_003312"
     CDS             complement(<1..306)
                     /locus_tag="IT892_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA acetyltransferase"
                     /protein_id="HAP3136495.1"
                     /translation="MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKID
                     SQHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAI
                     "
     gene            complement(337..1659)
                     /locus_tag="IT892_003313"
     CDS             complement(337..1659)
                     /locus_tag="IT892_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00366 family protein"
                     /protein_id="HAP3136496.1"
                     /translation="MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPI
                     SMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVT
                     FFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPL
                     LAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPK
                     LLMEEADFQKQLPKDAPPSERLEESRILTLIIGALGIAYLAMYFSEHGFNITINTVNL
                     MFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFI
                     NVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVIPAAQALGADLGKSVMAIAYG
                     EQWMNMAQPFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF"
     gene            complement(1656..2306)
                     /locus_tag="IT892_003314"
     CDS             complement(1656..2306)
                     /locus_tag="IT892_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit B"
                     /protein_id="HAP3136497.1"
                     /translation="MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQ
                     SENGFLGLGPVTTAHPDLVNAGGQPCGVLPGAAMFDSAMSFALIRGGHIDACVLGGLQ
                     VDEEANLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTA
                     QHAVHMLVTELAVFRFIDGKMWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL"
     gene            complement(2306..2968)
                     /gene="atoD"
                     /locus_tag="IT892_003315"
     CDS             complement(2306..2968)
                     /gene="atoD"
                     /locus_tag="IT892_003315"
                     /EC_number="2.8.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate CoA-transferase subunit alpha"
                     /protein_id="HAP3136498.1"
                     /translation="MKTKLMTLQDATGFFRDGMTIMVGGFMGIGTPSRLVEALLESGV
                     RDLTLIANDTAFVDTGIGPLIVNGRVRKVIASHIGTNPETGRRMISGEMDVVLVPQGT
                     LIEQIRCGGAGLGGFLTPTGVGTVVEEGKQTLTLDGKTWLLERPLRADLALIRAHRCD
                     TLGNLTYQLSARNFNPLIALAADITLVEPDELVETGELQPDHIVTPGAVIDHIIVSQE
                     SK"
     gene            complement(3164..4549)
                     /gene="atoC"
                     /locus_tag="IT892_003316"
     CDS             complement(3164..4549)
                     /gene="atoC"
                     /locus_tag="IT892_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetoacetate metabolism transcriptional
                     regulator AtoC"
                     /protein_id="HAP3136499.1"
                     /translation="MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLF
                     ADIHPDVVLMDIRMPEMDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDY
                     VIKPFDLDELNLIVQRALQLQSMKKEIRHLHQALSTSWQWGHILTNSPAMMDICKDTA
                     KIALSQASVLISGESGTGKELIARAIHYNSRRAKGPFIKVNCAALPESLLESELFGHE
                     KGAFTGAQTLRQGLFERANEGTLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIK
                     VDIRIIAATNRDLQAMVKEGTFREDLFYRLNVIHLILPPLRDRREDISLLANHFLQKF
                     SSENQRDIIDIDPMAMSLLTAWSWPGNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQ
                     PVCNAGEAKTAPVGERNLKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYK
                     LQEYGIDPADV"
     gene            complement(4546..6372)
                     /gene="atoS"
                     /locus_tag="IT892_003317"
     CDS             complement(4546..6372)
                     /gene="atoS"
                     /locus_tag="IT892_003317"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     AtoS"
                     /protein_id="HAP3136500.1"
                     /translation="MHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVL
                     SEKEKKLSAVVNLLNQALGDRYDLYIDLPREERIRALNAELAPITENITHAFPGIGAG
                     YYNKMLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSML
                     PIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANI
                     DIITDGLSTLAQNIPTRLPQLPGEMGQISQSVNNLAQALRETRTLNDLIIENAADGVI
                     AIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQFYSPVLDTLEHGTEHVALE
                     ISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGEL
                     MAGVAHEVRNPLTAIRGYVQILRQQTSDPIHQEYLSVVLKEIDSINKVIQQLLEFSRP
                     RHSQWQQVSLNALVEETLVLVQTAGVQARVDFISELDNELSPINADRELLKQVLLNIL
                     INAVQAISARGKIRIQTWQYSDSQQAISIEDNGCGIDLSLQKKIFDPFFTTKASGTGL
                     GLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV"
     gene            6539..9388
                     /gene="rcsC"
                     /locus_tag="IT892_003318"
     CDS             6539..9388
                     /gene="rcsC"
                     /locus_tag="IT892_003318"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RcsC"
                     /protein_id="HAP3136501.1"
                     /translation="MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQR
                     ESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQADVPAF
                     EPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
                     RDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANR
                     LQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKGDPRWMQERSW
                     FGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLA
                     RMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLN
                     MLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRV
                     KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLV
                     TAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLG
                     LYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDT
                     GVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGS
                     QFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQE
                     PTPEDVLITDEVVSKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARI
                     YLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTAND
                     GVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRC
                     LESGMDSCLSKPVTLDVIKQTLTLYAERVRKSRDS"
     gene            complement(9588..10238)
                     /gene="rcsB"
                     /locus_tag="IT892_003319"
     CDS             complement(9588..10238)
                     /gene="rcsB"
                     /locus_tag="IT892_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsB"
                     /protein_id="HAP3136502.1"
                     /translation="MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINN
                     LPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLD
                     IEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
                     LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD"
     gene            complement(10255..12927)
                     /gene="rcsD"
                     /locus_tag="IT892_003320"
     CDS             complement(10255..12927)
                     /gene="rcsD"
                     /locus_tag="IT892_003320"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase RcsD"
                     /protein_id="HAP3136503.1"
                     /translation="MRQKETTATTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNA
                     WLKDKSYQIVDITHAIQKRVDNWRYVTWQIYDNIAATTSPSSGEGLQETRLKQDVYYL
                     EKPRRKTEALIFGSHDNSTLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLVLIST
                     LPLKDLTSGFKESTVSDIVDSRRAEMLQQANALDERESFSNMRRLAWQNGHYFTLRTT
                     FNQPGHLATVVAFDLPINDLIPPGMPLDSFRLEPDATATGNNDNEKEGTDSVSIHFNS
                     TKIEISSALNSTDMRLVWQVPYGTLLLDTLQNILLPLLLNIGLLALALFGYTTFRHFS
                     SRSTENVPSTAVNNELRILRAINEEIVSLLPLGLLVHDQESNRTVISNKIADHLLPHL
                     NLQNITTMAEQHQGIIQATINNELYEIRMFRSQVAPRTQIFIIRDQDREVLVNKKLKQ
                     AQRLYEKNQQGRMIFMKNIGDALKEPAQSLAESAAKLNAPESKQLANQADVLVRLVDE
                     IQLANMLADDSWKSETVLFSVQDLIDEVVPSVLPAIKRKGLQLLINNHLKAHDMRRGD
                     RDALRRILLLLMQYAVTSTQLGKITLEVDQDESSEDRLTFRILDTGEGVSIHEMDNLH
                     FPFINQTQNDRYGKADPLAFWLSDQLARKLGGHLNIKTRDGLGTRYSVHIKMLAADPE
                     VEEEEERLLDDVCVMVDVTSAEIRNIVTRQLENWGATCTTPDERLISQDYDIFLTDNP
                     SNLTASGLLLSDDESGVREIGPGQLCVNFNMSNAMQEAVLQLIEVQLAQEEVTESPLG
                     GDENAQLHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPG
                     KQLCETLEHLIREKDVPGIEKYISDIDSYVKSLL"
     gene            13666..14769
                     /gene="ompC"
                     /locus_tag="IT892_003321"
     CDS             13666..14769
                     /gene="ompC"
                     /locus_tag="IT892_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HAP3136504.1"
                     /translation="MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNKDVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQIQGNSAENENNSWTRVAFAGLK
                     FQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGL
                     VDGLNFAVQYQGKNGNPSGEGFTSGVTNNGRDALRQNGDGVGGSITYDYEGFGIGGAI
                     SSSKRTDAQNTAAYIGNGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANK
                     AQNFEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGATYYFNKNMSTY
                     VDYKINLLDDNQFTRDAGINTDNIVALGLVYQF"
     gene            14881..15936
                     /gene="apbE"
                     /locus_tag="IT892_003322"
     CDS             14881..15936
                     /gene="apbE"
                     /locus_tag="IT892_003322"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase ApbE"
                     /protein_id="HAP3136505.1"
                     /translation="MEISFTRVALLAAALFFVGCDQKPQPAKTHATEVTVLEGKTMGT
                     FWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVSEA
                     MADIVTTSLRIGAKTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQH
                     LTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALNSR
                     GMNGEGLPWRVAIQKPTDKENAVQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQ
                     TGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPEKAKEVVRREGLAVYMITKEGDSF
                     KTWMSPQFKSFLVSEKN"
     gene            16010..17074
                     /gene="ada"
                     /locus_tag="IT892_003323"
     CDS             16010..17074
                     /gene="ada"
                     /locus_tag="IT892_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-binding transcriptional
                     regulator/O6-methylguanine-DNA methyltransferase Ada"
                     /protein_id="HAP3136506.1"
                     /translation="MKKATCLTDDQRWQSVLARDPNADGEFVFAVRTTGIFCRPSCRA
                     RHALRENVSFYANASEALAAGFRPCKRCQPEKANAQQHRLDKITHACRLLEQETPVTL
                     EALADQVAMSPFHLHRLFKATTGMTPKAWQQAWCARRLRESLAKGESVTTSILNAGFP
                     DSSSYYRKADETLGMTAKQFRHGGENLAVRYALADCELGRCLVAESERGICAILLGDD
                     DATLISELQQMFPAADNAPADLMFQQHVREVIASLNQRNTPLTLPLDIRGTAFQQQVW
                     QALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIIIPCHRVVRGDGTLSGY
                     RWGVSRKAQLLRREAENEER"
     gene            17074..17724
                     /gene="alkB"
                     /locus_tag="IT892_003324"
     CDS             17074..17724
                     /gene="alkB"
                     /locus_tag="IT892_003324"
                     /EC_number="1.14.11.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA oxidative demethylase AlkB"
                     /protein_id="HAP3136507.1"
                     /translation="MLDLFADAEPWQEPLAAGAVILRRFAFNAAEQLIRDINDVASQS
                     PFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQR
                     AATAAGYPDFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLK
                     RNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGKKE"
     gene            17800..19443
                     /gene="yojI"
                     /locus_tag="IT892_003325"
     CDS             17800..19443
                     /gene="yojI"
                     /locus_tag="IT892_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin J25 efflux ABC transporter YojI"
                     /protein_id="HAP3136508.1"
                     /translation="MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETA
                     DTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTHVERIEQL
                     GSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAIT
                     IWGGFVLVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDA
                     QEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLR
                     TPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPNWQTLELRNVTFAYQD
                     NAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVSGEQP
                     EDYRKLFSAVFTDVWLFDQLLGPEGKPANPQLVEKWLAQLKMAHKLELSNGRIVNLKL
                     SKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISH
                     DDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA"
     gene            19661..21307
                     /gene="mqo"
                     /locus_tag="IT892_003326"
     CDS             19661..21307
                     /gene="mqo"
                     /locus_tag="IT892_003326"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HAP3136509.1"
                     /translation="MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSA
                     TLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISI
                     EKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
                     QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIAS
                     LQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLL
                     QESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLD
                     GKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVML
                     SEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIA
                     ALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERE
                     LQYTSEVLGLNYDKPQAADSTPKPQLKPQPVQKEVADIAL"
BASE COUNT         5232 a         5226 c         5613 g         5330 t
ORIGIN      
        1 aatggcctgg gcggcaagcg ccacactttt aagacccgaa ccacatactt tattgaccgt
       61 gaatccgcac accgtttctg ccagcccgct ttttaacagt gcctgacgcg ccggattttg
      121 ccccagcccg gcttgtaaca cgttacccat aatcacttca tcaacgtgtt gtgaatcgat
      181 ttttgcacgt tcaatggcgg ctttaattac tgtcgccccc aggtcgatgg cgctggtgga
      241 agcgagtgaa ccgttaaaac taccgatagc agtacgtacc gcactgacga tgacacaatt
      301 tttcatttta tattccttct gtttgtaggg gtgccgtcag aacagcgtta aaccaatgac
      361 gaaaatgaca ccggagaaga gcagggcagt gatgcagtag cccatgatgt cgcggacacc
      421 gagtccggcg attgccagtg ctggcagcgc ccagaatggt tgtgccatgt tcatccattg
      481 ctcgccgtag gcgatcgcca ttaccgattt accgagatca gcgcccagcg cctgggctgc
      541 gggtatcacg aaaggtccct gaataaccca gtgaccgccg ccagacggaa cggcgaagtt
      601 aatcagtgca gaactaaaaa aggtcattac cgggaaggtg tctttgttcg caacattgat
      661 gaagaattcg gtaatgagtc cgcccagacc ggaatgctcc atcatcagtt ggatcccagc
      721 gtagaagggg aattgcacca gaataccggc agtactgcgt gctgccgcgc tgatagcacg
      781 catataagcc attggcgttt tatgtagcag cagacccgca atcataaaca tcaggttgac
      841 ggtattgatg gtgatgttga agccatgttc gctgaagtac atcgcaaggt aagcgatacc
      901 gagtgcgccg atgatcaacg tcagaatgcg gctttcttcc agtcgctcgg atggtggggc
      961 atctttcggt agctgctttt gaaaatcagc ctcttccatg agtagttttg gatcgatact
     1021 caccacgtca gacggttttg gcatcatcat gcgggtgata aatggcatca ccacaatcaa
     1081 cgccacagtg atgaaaatgt taaaaccact gaacagagta tcgcccaccg ggatcagccc
     1141 ggcgatatgc tcaaccgggt tgcccggtgt tgcagccaac agaggcattg atccagagaa
     1201 gccgccaccc caggtgagaa aaccaatgta ggcgcaggca atgagcaacg gataatcaga
     1261 accggggact cgccgggcga cttcacgggc aaacattgcg ccgacaacca aaccaaatcc
     1321 ccagttgatg acacaagcga ctgaaccgaa gaaagtgacc agcatgacgc cctgtacggg
     1381 cgtctttgcg gcggaggcgg cagtacgcag caaacttttc accggagcag agctggcaag
     1441 ggcatgaccg gtaacgatga taagcgccat ctgcatacca aacgccagca agttccagaa
     1501 accgtcaccc cacattttca ccatgctgat cggcgtttgt ggtgttaacc aaagcgcgat
     1561 cacgaatgtt agcaatgtca gcaacatggc aaagatcagt ggatcgggaa gccaccggct
     1621 gacaaaacgc gtcataaaac gcgatatgcg accaatcata aatcaccccg ttgcgtattc
     1681 agatcggcgg cgacttcaaa ccgagcttct gttttggcac gcacggtggc taaatcacac
     1741 ccgtcggcaa tttcggtgag ccacattttg ccgtcaataa aacgaaagac agccagttca
     1801 gtaaccagca tatgcaccgc atgttgcgca gtgagtggca tggtgcagcg gcgcaaaatt
     1861 tttgctgaac catctttggc gcaatgttcc atggcgatga tcactttgcg cgacccggtc
     1921 accagatcca tcgcgccacc cataccgggc accattttcc caggcactac ccagttcgcg
     1981 aggtttgctt cttcgtctac ttgcaaaccg ccgagcacgc aggcatcaat atgaccgcca
     2041 cggattagcg caaatgacat ggcgctatca aacatggctg caccgggtaa aacaccgcac
     2101 ggttgcccgc cagcgttcac cagatctgga tgcgctgtcg tgaccgggcc taaaccgagg
     2161 aagccgtttt ccgattgcag agtgatatga ataccctccg gtaaataatt ggcgaccatt
     2221 gtgggtaaac cgatccctaa gttaacgatg tcaccatcac gaagctcttg cgccacacgg
     2281 cgcgcaatac gttgtttcgc atccattatt tgctctcctg tgaaacgatg atgtggtcga
     2341 taacggcacc aggggtgaca atatggtcag gttgcagctc gccggtttcg accagttcat
     2401 ctggctctac cagcgtgata tcagccgcaa gggctatcag ggggttaaag ttgcgggcgc
     2461 taagttgata ggtcaggttg ccaagtgtgt cgcaacgatg agcgcgaatt agcgccaggt
     2521 cggcgcgcag tgggcgttcg agcagccagg ttttaccgtc gagtgtcagt gtctgtttgc
     2581 cttcctctac gacggtgccg acacccgttg gggtgagaaa accaccaagt ccagctccac
     2641 cacagcgaat ttgctcgatt agcgtacctt gcggcaccag aacgacgtcc atctcaccag
     2701 atatcatgcg ccgacctgtt tccgggttgg tgccgatatg tgaagcaatc actttgcgga
     2761 ctcgaccatt gacgatgagc ggaccgatgc cggtatcaac aaacgcggta tcattggcta
     2821 tcaatgtcag gtcgcgaaca ccagattcca gtaatgcttc aaccaggcgg gatggagtgc
     2881 caatccccat aaatccgccc accatgatgg tcatgccgtc acgaaagaag ccggtggcgt
     2941 cttgtaatgt catcaatttt gttttcattt tttatccctc ttgcatacac cgttgtgggt
     3001 acagtcaggc aatagcaagg ggagtgccag aatgagatta ttggatttag ttatttaact
     3061 aattgaatat gaagggataa attggatggg gatttataag gagaatgagc ggctatgcag
     3121 aaaattgcgc actgtgcaaa tttctgcata gcaagttttg gcgttataca tccgccggat
     3181 cgataccgta ttcctggagt ttatacatca atgcacggcg actgatgccc agcattaaag
     3241 cagtgcgggt tcggtttcct tcttgttgtt ccagcacttc cataatgatg cgtttttcga
     3301 cgcgtttaat ttcctctttt aaattacgct caccgacagg ggctgttttt gcctcaccag
     3361 cattacagac tggctgacga atctgcggcg gaagatcctc agagaaaatg atcgggcctg
     3421 agttcatcac gacggcgcgt tcaatgacgt tggaaagctc tcgaatatta cccggccatg
     3481 accaggcggt aagcagcgac attgccatcg gatcgatgtc gataatatcg cgctgattct
     3541 cactactgaa tttttgcaaa aagtgattag ctaacaggga aatatcttcc cggcgatcgc
     3601 gcagaggcgg cagtattaaa tgaataacgt taaggcgata aaagagatct tcacggaagg
     3661 tgccttcttt caccattgcc tgcaagtcgc ggttggtggc agcaatgatg cggatatcaa
     3721 cttttatggt ctgatggccg ccaatccgtt caaattcccg ttcctgcaga atgcgtagta
     3781 atttggcttg cagtacgagc ggcatttcgc caatttcgtc gaggagcaga gtaccttcgt
     3841 tggctcgttc aaataatccc tgacgcaagg tttgtgcacc agtaaatgca cctttttcat
     3901 gaccaaacag ttcactttcg agcaacgatt ccggcagcgc cgcgcagttg actttaatga
     3961 acggcccctt tgcccgccgc gaattgtagt gaatcgctct ggcaatcaac tctttcccgg
     4021 tgccgctttc accgctaatc aagacgctgg cctgagaaag ggcaattttg gcggtgtctt
     4081 tgcagatgtc catcatcgcc gggctgttgg tgagaatgtg cccccattgc cagctggtgc
     4141 tcagtgcctg gtgcagatga cggatctctt ttttcattga ctggagttgt aaagcgcgct
     4201 gaacgattaa attcaactca tcgagatcaa acggtttaat aacatagtcg aaggctccgc
     4261 agcgtagcgc ttcgacggcg gtttccactt ccgcataggc cgtcatcaga ataacgggtg
     4321 tccgggtctc atggctgcgc atctccttta gtgccttgat gccgtccatc tctggcatgc
     4381 ggatatccat caacaccaca tcagggtgaa tatcggcaaa caggtgtaat gctgtgcgtc
     4441 cgttgttcgc acaatgtgtt tcgaatcctt gtagtgcaaa agcggtgctc agcatacggc
     4501 gaacattatc ttcatcatcc acaataagga tgcgattaat agcagtcata cagtctgatt
     4561 tccctgcggg ttgatcggta aaataagcgt gaaggttgcg ccgtagcccg gcaaactggc
     4621 gacgcgaata tcaccctgat gggcattaat gatgcgttga cttaacgcca gcccaagccc
     4681 ggttcctgag gctttggtgg tgaaaaaggg atcgaagatc tttttttgca gcgagagatc
     4741 aatgccacag ccgttgtcct ctatcgaaat ggcctgttgt gagtcgctgt attgccaggt
     4801 ttgaatgcga attttccctc gtgcgctgat agcctggacg gcattgatca ggatattcag
     4861 tagtacctgt ttgagcagtt cacgatcggc gttaatcggg cttaattcat tatccagttc
     4921 gcttatgaag tcgacccgcg cttgtacgcc ggcggtttgt accagtacca gagtttcttc
     4981 aaccaatgca ttgaggctga cttgttgcca ttgactgtgg cgtggacgtg aaaattcgag
     5041 caattgctga ataactttgt taattgaatc gatttctttg agtactacgg acagatattc
     5101 ctgatgtatt gggtcactgg tttgttggcg caagatctgt acataaccac gaatagccgt
     5161 taacggatta cgtacttcat gcgcgacgcc agccatcagc tcacccagtg tggcgaggcg
     5221 ttctgcttgc gccatgcggc gctgggtttc tttgcgggca gttaaatcag agaaaatcac
     5281 caaagcacct atcatttcac cgtgcgtgtt atgaatacga ctggtagtga cactgagttc
     5341 aatggtgcgg tcacgacctg gaaaactgat ctccagcgcc acatgttcgg tgccatgttc
     5401 cagcgtatcc agtactggac tgtagaactg agtattgtcg aacaacatgg agtaaggctg
     5461 ccctaccagt tcatggcgtt gatagccagt gataacttct gctgctgggt tcatggtggt
     5521 tacatcaccc tggcggtcaa tggcaatgac gccatcggca gcgttttcaa taatcagatc
     5581 gttaagtgtc cgcgtttcac gcagtgcctg ggcgaggtta ttaacactct gactgatttg
     5641 ccccatttca ccgggcaatt gtggtaatcg agtgggaata ttttgtgcca gagtcgagag
     5701 gccatcggtg atgatatcaa tattggcgct caggcgacgg gagaaaagga caatcaacag
     5761 caggcttatc agcaaaccag cggtgagcac aatgataatc ctcacatcca ttttccaggc
     5821 ctggcggcga atatcttcgg ttaattcatt ggcccagata tagccgagga tttcaccatt
     5881 acgctcaatg gggagcattg aattcaaaat atcgccgcgc acctgcctgc ctgaataaac
     5941 taaaggggta tttgtacgca tcacttcgcg accagggtga tctgcggcaa tggtaacgcc
     6001 gacattattc tgatatagcg ctgaaggcgc gtaggtgatt atcgcatcca gcattttgtt
     6061 gtaataacca gcaccgatgc cagggaaggc gtgagtgata ttttcggtaa tgggggcaag
     6121 ttctgcattt aatgcgcgga tacgctcctc acgtggtaag tcgatgtaga gatcatagcg
     6181 atcgcctagt gcctgattaa gcaggttgac cacggcagaa agttttttct ctttttcaga
     6241 taagactgct gaacgtcctt ccgtttctac gatataacca atagtaagcg ttgggacaat
     6301 gaccatcagg attgccatca ggatcatttg attgcgtaag cggcgtggat aaatccactt
     6361 catataatgc atgctgaaat ccactagtct tgtccggtat atgacgatta tcagaggtta
     6421 aggtgatgat ttctcggcgg tgtatcatat tccagagaag agagaacatt gcggtaacac
     6481 gcttttaccg ctaccttaac cacactccat cggtcacctg aggcggagct tcgccccttt
     6541 gaaatacctt gcttcttttc gtacaaccct gaaagcctcg cgctacatgt tcagagcatt
     6601 ggcgttagtg ctctggctgt tgattgcttt ttcatccgtt ttttacatcg ttaatgcgtt
     6661 acatcagcga gaatcggaaa ttcgtcagga atttaatctg agttccgatc aggctcagcg
     6721 ctttattcaa cgcacctctg atgtgatgaa agagctgaag tacatcgccg aaaatcgctt
     6781 atcggcagaa aacggtgtgc tttccccgcg tggacgagaa acgcaggcgg atgtgcctgc
     6841 gtttgaaccg ctgtttgccg actccgattg ttccgcaatg agtaacacct ggcgaggttc
     6901 tctggagtca ttggcgtggt ttatgcgcta ctggcgcgat aatttttctg cggcttacga
     6961 tctaaaccgg gtatttttaa tcggcagcga taacctctgc atggccaatt tcggtctgcg
     7021 tgatatgcca gtggaacgcg ataccgcgtt gaaagctttg catgaacgca tcaataaata
     7081 tcgaaatgca ccacaagatg atagcggcag taacctctac tggatcagcg aaggtccgcg
     7141 ccctggcgtc gggtattttt acgcgttgac gccagtttat ctggcgaacc ggttgcaggc
     7201 gcttttgggt gtcgagcaga ccatccggat ggagaacttt ttcttaccgg gtacgttgcc
     7261 gatgggggtt accattcttg atgaaaatgg tcataccctg atttcgctta ccggaccaga
     7321 aagtaaaatt aagggcgatc ctcgctggat gcaggaacgc tcctggtttg gctatacgga
     7381 agggttccgg gagctggtgc tgaagaaaaa tctgccaccc tcatcgctaa gcatcgtgta
     7441 ttcggtgccg gttgataagg tgctggaacg cattcgcatg ttgatcctta acgcaatttt
     7501 gctgaatgtg cttgccggag ctgcattgtt tactctcgca cggatgtacg agcgacgtat
     7561 tttcattccg gcggaaagcg acgccctgcg actggaagaa catgagcagt tcaatcgcaa
     7621 gattgtcgcc tccgcgccag tgggtatctg cattttgcgt accgctgatg gcgtcaatat
     7681 tttaagtaac gaactggcgc atacctatct caatatgctt acgcatgagg accgccaacg
     7741 actgacgcaa attatctgtg ggcagcaggt caattttgtt gatgtcctga ccagcaacaa
     7801 taccaatctg caaatcagct tcgtccattc gcgctatcgt aatgaaaacg tggccatttg
     7861 tgtgctggtg gatgtttctt cgcgcgtgaa gatggaagag tcgttgcagg agatggcaca
     7921 agcagcggaa caggcgagcc agtcaaaatc gatgttcctt gccaccgtca gtcatgagct
     7981 gcgaacgccg ctgtatggca ttatcggtaa cctggatctg ttgcaaacca aagagttacc
     8041 gaaaggcgtc gatcggctgg tgacggcaat gaacaactct tccagcctgt tgttgaaaat
     8101 tatcagcgat attctcgatt tctcgaagat tgaatcggaa cagttgaaga tcgaaccgcg
     8161 tgagttttca ccgcgtgaag tgatgaacca catcaccgcc aactatttac cgctggtggt
     8221 acgcaagcag ttaggcttgt actgctttat tgaaccggat gtgccagtgg ccttaaatgg
     8281 cgacccgatg cgtttacagc aggtcatctc caacctgttg agtaacgcca taaaattcac
     8341 cgataccggc tgtatagttt tgcatgttcg cgcggatggc gattatctct ctatccgtgt
     8401 tcgcgatacc ggcgtgggga taccggcgaa agaagtggtg cgcttgtttg atcccttctt
     8461 ccaggtcgga acgggcgtac agcgtaattt ccaggggacc ggtctgggtc tggcgatttg
     8521 tgaaaaactg atcagcatga tggacggcga tatctcggta gattcagaac cgggaatggg
     8581 cagccagttt accgtgcgta ttccgttgta cggcgctcag tacccgcaga aaaaaggcgt
     8641 ggaagggttg agtggtaaac gctgctggct ggcggtccgc aatgcgtcgc tctgtcagtt
     8701 cctggaaacc agtttgcagc gcagcggcat cgtcgttaca acatacgaag ggcaggaacc
     8761 gactcccgaa gatgtgttga tcactgacga ggtagtgagt aaaaaatggc agggcagagc
     8821 ggtagtgacc ttctgtcgtc gccatattgg tattccgctg gagaaagcgc caggggagtg
     8881 ggtacacagt gtggctgctc cgcatgagct accggcattg ttggcgcgta tttatttgat
     8941 cgagatggag agcgacgatc ctgctaacgc tctgccgtca acggacaaag cggtcagcga
     9001 taatgacgat atgatgattc tggtcgtgga tgatcatccg attaaccggc gtttgctggc
     9061 agatcagttg ggatcgttgg gctatcaatg taaaaccgcg aatgatggcg tcgatgcgct
     9121 taatgtactt agcaagaatc atattgatat cgtgcttagc gacgtcaaca tgccaaatat
     9181 ggatggttac cgcttgacgc aacgcattcg tcagttggga ctgacgttgc cggtaatcgg
     9241 agtaactgct aatgcgttgg ctgaagagaa gcagcggtgt ctggagtccg gtatggacag
     9301 ctgcctgtcg aagccggtaa cgctggatgt gataaaacag acgctgacgt tatatgccga
     9361 gagggtcagg aaatcgcggg attcgtagga cggataaggc gtttacgccg catccggcat
     9421 tcagtgcaaa tgccagatgc gacgctgacg cgtcttatct ggcctacttt aatgtaattt
     9481 gttgaaataa tgggaatcgt aggccggata aggcgtttac gccgcatccg gcaatcggtg
     9541 caaatgccag ataagacact aacgcgtctt atctggccta caggtgatta gtctttatct
     9601 gccggactta aggtcactga agagagataa ttcagcaggg cgatatcgtt ctcgacaccc
     9661 agcttcatca tcgcagattt cttctggcta ctgatggttt taatactgcg gttcagcttt
     9721 ttagcgatct cggtcaccag gaagccttcc gcaaacaggc gcagaacttc actctctttt
     9781 ggcgagagac gcttgtcacc gtaaccacca gcactgattt tttccaacag gcgagaaacg
     9841 ctttccgggg taaatttctt ccctttctgc agcgcggcga gagctttcgg cagatcggtc
     9901 ggtgcacctt gtttcagcac gatcccttcg atatccagat ccaataccgc actaagaatc
     9961 gccgggttgt tgttcatagt cagaacaatg atcgacaggc ttgggaaatg gcgcttgatg
    10021 tacttgatta aggtaatgcc atcgccgtac ttatcgccag gcatggagag atcggtaatc
    10081 aacacatgcg catccagttt cggcaggttg ttgatcagtg ctgtagagtc ttcaaattcg
    10141 ccgacaacat tcacccactc aatttgctca agtgatttgc gaataccgaa caagactatc
    10201 ggatggtcat cggcaataat tacgttcata ttgttcatgt aataggctac cttgctacag
    10261 caagctcttg acataactgt caatgtcgct gatgtatttt tctattcctg gaacatcctt
    10321 ctcacgaatc agatgttcca gcgtttcaca taactgcttg ccgggtacca gatttagcat
    10381 ggcaaatacg cctttaagac gatgagccgt ttgggctaac gcagcaaagt cactggttgc
    10441 tgcttcagta tacagcctct taacatcatc cggtactgtg tctacaaaga gcgcataata
    10501 gccgctggca tggagttgcg cattttcatc tccgcccaga ggcgattctg tcacctcttc
    10561 ctgcgccagt tgcacttcaa ttaattgtaa gaccgcttcc tgcatagcgt tgctcatatt
    10621 gaagttgacg cacaattgac caggcccaat ttcccgtacg ccagactcat catcgcttaa
    10681 aagcaagcca gaggcagtaa gattagacgg attatccgtt aaaaagatat cataatcttg
    10741 actaattaat ctttcatcgg gtgtggtaca ggttgcaccc caattttcta actggcgagt
    10801 gacaatattc cgaatttctg ccgaagtaac atccaccatt acgcagacat catccagtaa
    10861 acgctcttct tcctcttcaa cttccgggtc agctgcgagc attttgatat gcacagagta
    10921 gcgtgtacca agcccatccc gcgttttgat gtttaaatga ccgcccagtt tacgtgccag
    10981 ttgatcgctc agccagaatg ccagcgggtc cgccttgcca tagcgatcgt tttgggtctg
    11041 gttgataaac gggaagtgca aattatccat ttcatgaata cttacgcctt ctcccgtgtc
    11101 cagaatgcgg aacgtcaggc ggtcttcgga ggactcatcc tgatcaacct caagggtgat
    11161 ttttcccaat tgcgttgagg tcacggcata ttgcatcagt agcagcaaaa tacgtcgtaa
    11221 ggcatcgcga tcgccgcggc gcatatcgtg tgctttcaga tgattgttaa tcagcagttg
    11281 cagaccttta cgcttgatgg caggcaacac tgaaggcaca acttcatcaa ttaaatcctg
    11341 cacggagaac agcaccgtct cacttttcca gctatcatcc gcaagcatgt tcgctaactg
    11401 tatttcatca accagccgca ccagcacatc tgcctgattc gccagttgtt tgctttccgg
    11461 ggcgttgagt ttagccgcgc tctccgccag ggactgtgcg ggttctttca gcgcatcgcc
    11521 aatgtttttc ataaagatca tccgcccctg ctggtttttc tcatacagac gctgcgcctg
    11581 cttgagtttc ttgtttacca gcacttcgcg atcctgatcg cgaataatga aaatttgtgt
    11641 gcgcggcgcg acctggctgc ggaacatgcg gatctcatac agctcgttat tgatcgtcgc
    11701 ctgaataatc ccctgatgct gttccgccat ggtggtgatg ttttgcagat tcaaatgcgg
    11761 cagcaaatga tcggcaattt tgttacttat gacagtgcgg ttcgattcct gatcgtgaac
    11821 cagcaggccg agcggcagca gtgagactat ctcttcattg attgcccgta aaatgcgcaa
    11881 ttcgttattg accgccgtgc tggggacgtt ttctgtactg cggctggaga aatggcggaa
    11941 tgtggtatag ccaaataacg ccagcgccag caaaccgatg ttcagcagca gtggcagcag
    12001 aatgttttgc aacgtatcca gcaataaggt gccataagga acctgccaga ccaggcgcat
    12061 atcggtagag ttgagtgccg aggagatttc aatcttcgta ctgttaaagt ggatactgac
    12121 gctatccgtc ccttctttct cattatcatt gtttcccgtt gccgtcgcgt ctggctcaag
    12181 gcggaaactg tccagcggca tacccggtgg gatcaaatca ttaatcggca gatcaaaagc
    12241 cacgaccgtt gccagatgtc ctggctggtt aaaggtagta cgcaatgtaa agtaatgacc
    12301 gttctgccag gccaggcggc gcatgttaga aaagctttcg cgttcatcga gggcgttggc
    12361 ctgttgcaac atctctgcac gacgtgaatc aacaatgtcg ctgacggtcg attctttaaa
    12421 tccggaggtg agatctttaa ggggtagggt tgagatcagc accagactgt tatcctgacc
    12481 attcaggtaa tacatcgacc acggtacatt ttctgcgccc cacaatgtat ccagataagt
    12541 ggacatccgc tgagtcatct caagcgttga gttgtcgtga gagccaaaga ttaacgcttc
    12601 cgttttgcgg cgtggtttct ccagatagta gacatcctgt ttcaggcgcg tctcttgtaa
    12661 accttcgccg gaggaggggg aggtcgtcgc ggcaatgttg tcgtagatct gccaggtcac
    12721 gtaacgccag ttatcgacgc gcttttggat agcatgggta atgtcgacaa tctggtaact
    12781 tttatctttc agccaggcgt taacggcgct ttgtaccatt acacccatcg tcaccagtaa
    12841 cacaatgatc aacagtaaaa agaagcgggt aatgctcccc ggtaggagtg aaaagcgggt
    12901 cgtggccgtt gtctctttct gacgcattcg tgtttatgac ctgttaaaac ttcgcgaagt
    12961 gatagggcag tataaagggt acagtgtgaa attccagact cttacctgat tgatgattct
    13021 ctattctccc gtgatattta tcatcctgca ttgggggaaa tagatgtaca agcgccattt
    13081 tgctgtacaa ataacctaca aaaagcccaa caaaaataat tgcaaataaa caaagattgc
    13141 tggaaattat gcggatgtta attatttgtg aaatagttaa caagcgttat agtttttctg
    13201 tggtagcaca gaataatgaa aagtgtgtaa agaagggtaa aaaaaaccga atgcgaggca
    13261 tccggttgaa ataggggtaa acagacattc agaaatgaat gacggtaata aataaagtta
    13321 atgatgatag cgggagttat tctagttgcg agtgaaggtt ttgttttgac attcagtgct
    13381 gtcaaatact taagaataag ttattgattt taaccttgaa ttattattgc ttgatgttag
    13441 gtgcttattt cgccattccg caataatctt aaaaagttcc cttgcattta cattttgaaa
    13501 catctatagc gataaatgaa acatcttaaa agttttagta tcatattcgt gttggattat
    13561 tctgcatttt tggggagaat ggacttgccg actgattaat gagggttaat cagtatgcag
    13621 tggcataaaa aagcaaataa aggcatataa cagagggtta ataacatgaa agttaaagta
    13681 ctgtccctcc tggtcccagc tctgctggta gcaggcgcag caaacgctgc tgaagtttac
    13741 aacaaagacg gcaacaaatt agatctgtac ggtaaagtag acggcctgca ctatttctct
    13801 gacaacaaag atgtagatgg cgaccagacc tacatgcgtc ttggcttcaa aggtgaaact
    13861 caggttactg accagctgac cggttacggc cagtgggaat atcagatcca gggcaacagc
    13921 gctgaaaacg aaaacaactc ctggacccgt gtggcattcg caggtctgaa attccaggat
    13981 gtgggttctt tcgactacgg tcgtaactac ggcgttgttt atgacgtaac ttcctggacc
    14041 gacgtactgc cagaattcgg tggtgacacc tacggttctg acaacttcat gcagcagcgt
    14101 ggtaacggct tcgcgaccta ccgtaacact gacttcttcg gtctggttga cggcctgaac
    14161 tttgctgttc agtaccaggg taaaaacggc aacccatctg gtgaaggctt tactagtggc
    14221 gtaactaaca acggtcgtga cgcactgcgt caaaacggcg acggcgtcgg cggttctatc
    14281 acttatgatt acgaaggttt cggtatcggt ggtgcgatct ccagctccaa acgtactgat
    14341 gctcagaaca ccgctgctta catcggtaac ggcgaccgtg ctgaaaccta cactggtggt
    14401 ctgaaatacg acgctaacaa catctacctg gctgctcagt acacccagac ctacaacgca
    14461 actcgcgtag gttccctggg ttgggcgaac aaagcacaga acttcgaagc tgttgctcag
    14521 taccagttcg acttcggtct gcgtccgtcc ctggcttacc tgcagtctaa aggtaaaaac
    14581 ctgggtcgtg gctacgacga cgaagatatc ctgaaatatg ttgatgttgg tgctacctac
    14641 tacttcaaca aaaacatgtc cacctacgtt gactacaaaa tcaacctgct ggacgacaac
    14701 cagttcactc gtgacgctgg catcaacact gataacatcg tagctctggg tctggtttac
    14761 cagttctaat ctcgattgat atcgaacaaa gggcctgcgg gccctttttt cattgttttc
    14821 agcgtacaaa ctcagttttt tggtgtactc ttgcgaccgt tcgcatgagg ataatcacgt
    14881 atggaaataa gctttacccg cgtggcactg ctggctgccg cgctcttctt tgttggttgc
    14941 gatcaaaaac cacaacccgc caaaacccac gctactgaag ttaccgttct tgaaggcaaa
    15001 actatgggta ccttctggcg tgccagcatc ccgggcattg acgccaaacg cagcgccgaa
    15061 cttaaagaaa agattcagac ccaactggac gccgacgatc agctgctttc gacctataaa
    15121 aaagattccg cgctgatgcg ctttaacgac tcgcaaagtt tatcgccgtg gccggtaagt
    15181 gaagcgatgg ccgatatcgt caccacctcg ctgcgcattg gcgcgaagac cgatggcgcg
    15241 atggatataa ccgtcgggcc gctggtgaat ctgtggggct ttggcccgga acaacagccg
    15301 gttcaaattc cgagccagga acagatcgat gcgatgaaag ccaaaaccgg cttacagcac
    15361 ctgacggtca tcaatcagtc gcatcagcaa tatctgcaaa aagacctgcc ggatttatat
    15421 gtcgatctct ccaccgtcgg cgaaggctat gcggccgatc atttggcacg cttgatggag
    15481 caggaaggga tttcccgcta tctggtgtcg gtgggcggcg cgctgaacag ccgtggtatg
    15541 aacggtgaag gcctgccgtg gcgggtagcg attcaaaaac caaccgataa agaaaacgcg
    15601 gttcaggctg tggtggatat caacggtcat gggattagca cctctggcag ctaccgtaac
    15661 tattacgaac tggacggcaa acgtctttcc catgttatcg atccgcaaac cgggcgtccc
    15721 atcgaacaca atctggtatc cgtgacggtg attgctccga cggcgctgga agccgatgcc
    15781 tgggatactg gcttgatggt actcgggccg gagaaagcta aagaggttgt tcgccgggaa
    15841 gggctggcgg tttatatgat caccaaagaa ggcgatagct ttaaaacctg gatgtcacca
    15901 cagtttaaaa gcttccttgt cagcgaaaaa aattaaagcg caagattgtt ggtttttgcg
    15961 tgatggtgac cgggcagcct aaaggctatc cttaaccagg gagctgatta tgaaaaaagc
    16021 cacatgctta actgacgatc aacgctggca atctgtctta gcccgcgacc cgaatgccga
    16081 cggcgaattc gttttcgccg tgcgtaccac aggcatcttt tgccgtccgt cttgccgcgc
    16141 cagacatgct ttgcgggaaa acgtctcctt ctacgcaaat gccagcgagg cactcgccgc
    16201 tggctttcgc ccctgcaaac gttgtcagcc agaaaaagcc aatgcccagc aacatcggtt
    16261 ggataaaatc acccacgcgt gtcgactgct ggaacaggaa acgcctgtaa cgctggaagc
    16321 cttagccgac caggtggcga tgagtccatt tcatctacat cggttgttta aagcgactac
    16381 cggaatgacg cctaaagcct ggcaacaggc ctggtgcgct cgccgtttgc gcgaatcgct
    16441 ggcgaaaggg gagagcgtga cgacgtctat tcttaacgcc ggattccccg acagcagcag
    16501 ttactatcgc aaagctgacg aaacgctggg catgacggct aaacaattcc gtcacggtgg
    16561 cgaaaatctg gcggtgcgtt acgcgctggc tgattgtgag ctgggtcgtt gcctggtggc
    16621 agaaagcgag cgggggattt gcgcgatatt gctgggcgat gatgacgcga cactaatcag
    16681 cgagttgcag cagatgtttc ccgctgccga caacgcgcct gccgatctga tgtttcagca
    16741 acatgtgcgt gaagtgatcg ccagcctcaa tcaacgcaat acgccgctga cgttaccgct
    16801 ggacattcgc ggcactgctt ttcagcaaca agtctggcag gcactgcgca cgataccttg
    16861 cggtgaaacc gtcagttatc agcaactggc taacgccatc ggcaaaccga aagcggtacg
    16921 ggccgttgcc agcgcctgtg ccgccaacaa gctggctatc ataataccct gtcatcgggt
    16981 ggtccgtggt gatggcacac tttccggtta ccgctggggc gtgtcgcgta aagcgcaact
    17041 gctgcgccgc gaagctgaaa atgaggagag gtaatgttgg atctgtttgc cgatgctgaa
    17101 ccgtggcaag agccactggc ggctggtgcg gtaattttac ggcgttttgc ttttaacgct
    17161 gcggagcaac tgatccgcga tattaatgac gttgccagcc agtcgccgtt tcgccagatg
    17221 gtcacccccg ggggatatac catgtcggtg gcgatgacca actgtgggca tctgggctgg
    17281 acgacccatc ggcaaggtta tctctattcg cccattgatc cgcaaacaaa taaaccgtgg
    17341 cccgccatgc cacagagttt tcataattta tgtcaacgtg cggctacggc ggcgggctat
    17401 ccagatttcc agccagatgc ttgtcttatc aaccgctacg ctcctggcgc gaaactgtcg
    17461 ctgcatcagg ataaagacga accggatctg cgcgcgccaa ttgtttctgt ttctctgggc
    17521 ttacccgcga tttttcaatt tggcggcctg aaacgaaatg atccgctcaa acgtttgttg
    17581 ttggaacatg gcgatgtggt ggtatggggc ggtgaatcgc ggctgtttta tcacggtatt
    17641 caaccgttga aagcggggtt tcatccactc accatcgact gccgctacaa cctgacattc
    17701 cgtcaggcag gtaaaaaaga ataaaaataa gaattattat tgctgtgcgc gcgaagatgt
    17761 ttaaactgcg ggctgtaatt cattgtccgg gttttctgca tggaacttct tgtacttgtc
    17821 tggcggcagt atcgctggcc atttatcagt gtgatggcgc taagcctcgc cagtgcggca
    17881 ttaggcattg gcttaattgc ttttatcaat cagcgcctta tcgaaacggc ggataccagt
    17941 ctgctggtgt tgccggagtt tctgggatta ttgctgctgt tgatggcagt cactctcgga
    18001 tcgcaactgg cgctcaccac tttggggcat cacttcgttt accgactgcg tagtgaattt
    18061 atcaagcgga ttctggatac tcacgtcgag cgcattgaac aactcggtag cgcctcgttg
    18121 ctggcggggt taaccagcga tgtgcgcaat atcaccattg cttttgtgcg tctgccggaa
    18181 ctggtgcagg ggatcattct cactatcggt tcagcggcgt atctgtggat gctgtcgggc
    18241 aaaatgttgc tggtaacggc tatctggatg gcgatcacca tctggggcgg ttttgtgctg
    18301 gtggcgcggg tgtacaaaca tatggcgacc ctgcgtgaaa ccgaagacaa gctgtacacg
    18361 gattttcaaa ctgtacttga agggcgcaaa gagctgactc tgaaccggga acgcgccgag
    18421 tatgtgttta acaacctcta cattcctgat gcgcaagagt atcgccacca tattattcgc
    18481 gcagacacct tccatcttag tgccgtgaac tggtcaaaca tcatgatgct gggcgcaatc
    18541 ggcctggtgt tctggatggc gaacagcctc ggttgggctg ataccaacgt tgccgcgacc
    18601 tattcgttga cgcttttatt cctgcgtacg ccgctgcttt cggcggttgg cgcattgccg
    18661 acgctgctga cggcgcaggt ggcgtttaac aagctgaaca aattcgcgct cgcgcctttc
    18721 aaagcagagt ttccgcgccc gcaggcgttt cccaactggc aaacgctgga gctgcgtaac
    18781 gtgacgtttg cttatcagga taacgcgttt tccgttggtc cgattaatct caccatcaaa
    18841 cgtggcgagc tgctgtttct gattggcggc aacggtagcg gaaaatcgac gctggcgatg
    18901 ttgttgacgg gcttgtatca gccacaaagc ggcgaaatct tgctggatgg caaacctgtc
    18961 agcggcgaac aaccggaaga ttatcgcaaa ctgttttcgg cagtgtttac cgatgtctgg
    19021 ctgtttgatc aactgctggg gccggagggt aaacccgcta acccgcaact ggttgagaag
    19081 tggctggcgc agctgaaaat ggctcataag cttgagttaa gcaacgggcg tattgttaac
    19141 ctgaagttat caaaagggca gaaaaaacgc gtggcgctgt tgctggcgct ggcagaagaa
    19201 cgcgatatta tcctgctgga tgaatgggcg gcggatcagg atccacactt ccgtcgtgag
    19261 ttttatcagg tgttgctgcc gctgatgcag gagatgggta aaactatttt cgctatcagt
    19321 catgatgatc attactttat ccacgccgac cgcctgctgg aaatgcgcaa tgggcaactt
    19381 agcgagctga cgggcgaaga gcgcgatgcc gcttcgcgtg atgccgttgc ccggacggca
    19441 taatattacg acgctgacct ggcggactgc tgccgtcagg tcaatatgct aaaaatccct
    19501 tcatttctaa taaccctata attaatcaac gaaattataa tgtttctaaa attagaatat
    19561 aatttataaa cattatttaa atgttgttac ttaagtgtta ccgttgatgc cgcgcaaatc
    19621 tcacctgcaa taaagcgact aaaagtaagg cattaacaag atgaaaaaag tgactgccat
    19681 gctcttctcg atggccgtgg ggcttaatgc cgtttcgatg gcggcaaaag cgaaagcgtc
    19741 cgaggagcag gaaactgatg tactgttgat tggcggcggc attatgagcg ccacgttggg
    19801 gacctattta cgcgagctgg agcctgaatg gtcgatgacc atggtggagc gcctggaggg
    19861 tgtcgcgcag gagagttcga acggctggaa taacgccgga accgggcatt ctgcactgat
    19921 ggaactgaac tacaccccgc aaaacgccga tggcagcatc agtattgaaa aagcagtcgc
    19981 cattaacgaa gcatttcaga tttcccgcca gttctgggcg caccaggttg agcgcggcgt
    20041 gctgcgtact ccgcgttcat ttatcaatac cgttccgcat atgagctttg tctggggcga
    20101 ggataacgtc aatttcctgc gcgcccgtta cgccgcgttg caacaaagct cgctgtttcg
    20161 cggtatgcgt tactctgaag atcacgcgca gatcaaagag tgggcaccgt tagtgatgga
    20221 agggcgcgat ccgcaacaga aagtggcagc cacgcgtacg gaaattggta ccgatgtgaa
    20281 ctacggcgag atcacccgcc agttaattgc ttccttgcag aagaaatcta acttctcgct
    20341 gcaactcagc agcgaagtcc gcgccctaaa gcgtaatgac gataacacct ggaccgttac
    20401 cgttgccgat ctgaaaaatg gcactgcaca gaacattcgt gccaaatttg tctttatcgg
    20461 cgcgggcggt gcggcgctga agctgttaca ggaatcgggg attccggaag cgaaagacta
    20521 cgccggtttc ccggtgggcg gacagttcct tgtttcggaa aacccggacg tggttaatca
    20581 ccatctggcg aaggtttacg gtaaagcatc cgttggcgca ccaccgatgt cggttccgca
    20641 tatcgatacc cgcgttctgg acggtaaacg cgtagtgctg tttgggccat ttgccacctt
    20701 ctcaaccaaa ttcctcaaaa acggttcatt gtgggatcta atgagttcca ccaccacctc
    20761 taacgtgatg ccgatgatgc acgtcgggct ggataatttc gatctggtga aatatctggt
    20821 gagtcaggtg atgttgagtg aagaggatcg ttttgaagcg ttgaaagagt actatccgca
    20881 ggcgaaaaaa gaggactggc gtttgtggca agcggggcag cgcgtgcaga ttatcaagcg
    20941 tgatgccgag aaaggtggcg tactgcgtct gggtactgaa gtcgtcagtg accagcaagg
    21001 aaccattgcc gcgctcctgg gggcatcgcc aggggcgtca accgccgcgc cgattatgtt
    21061 gaatctgctg gaaaaagtat ttggcgatcg tgtttccagc ccgcaatggc aggctacgtt
    21121 gaaagcgatc gttccgtctt atggacgcaa gctgaacggt gatgtagcgg caacagaacg
    21181 cgagttgcag tacaccagcg aagtgctggg gttgaactac gacaagccgc aggcagcaga
    21241 tagtacgccg aaaccgcagt tgaaaccgca acccgttcaa aaagaagtgg cggatattgc
    21301 gttgtaatga tgcgccacat ccggcatggt atgccggatg tggcgtatgc tgataagacg
    21361 cgccagcgtc gcatcaggca accggctcgg gcgttagatg t
//
LOCUS       DACAOP010000084        20484 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.084, whole genome shotgun sequence.
ACCESSION   DACAOP010000084 DACAOP010000000
VERSION     DACAOP010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20484
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.084"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..924)
                     /gene="mdtH"
                     /locus_tag="IT892_003327"
     CDS             complement(<1..924)
                     /gene="mdtH"
                     /locus_tag="IT892_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309470.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtH"
                     /protein_id="HAP3136510.1"
                     /translation="MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWA
                     AVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLL
                     WFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
                     YDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLA
                     GYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHR
                     LMAGLLIMSLSMMPVGMVSGLQQLFTLICLFY"
     gene            1160..1744
                     /gene="rimJ"
                     /locus_tag="IT892_003328"
     CDS             1160..1744
                     /gene="rimJ"
                     /locus_tag="IT892_003328"
                     /EC_number="2.3.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S5-alanine
                     N-acetyltransferase"
                     /protein_id="HAP3136511.1"
                     /translation="MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKP
                     WEPVRDESHCYPSGWQARLGMINEFHKQGSAFYFGLFDPDEKEIIGVANFSNVVRGSF
                     HACYLGYSIGQKWQGKGLMFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLG
                     FEKEGYAKDYLLIDGQWRDHVLTALTTPDWTPGR"
     gene            1755..2402
                     /locus_tag="IT892_003329"
     CDS             1755..2402
                     /locus_tag="IT892_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF480 domain-containing protein"
                     /protein_id="HAP3136512.1"
                     /translation="MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNR
                     EPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVAL
                     ITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRE
                     NRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD"
     gene            2404..3327
                     /locus_tag="IT892_003330"
     CDS             2404..3327
                     /locus_tag="IT892_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP3136513.1"
                     /translation="MKKLRIGVVGLGGIAQKAWLPVLAAASDWTLQGAWSPTRAKALP
                     ICESWRIPYADSLSSLAASCDAVFVHSSTASHFDVVSTLLNAGVHVCVDKPLAENLRD
                     AERLVELAARKKLTLMVGFNRRFAPLYGELKTQLATAASLRMDKHRSNSVGPHDLYFT
                     LLDDYLHVVDTALWLSGGKASLDDGTLLTNDAGEMLFAEHHFSAGPLQITTCMHRRAG
                     SQRETVQAVTDGALIDITDMREWREERGQGVVHKPIPGWQSTLEQRGFVGCARHFIEC
                     VQNQTVPQTAGEQAVLAQRIVDKIWRDAMSE"
     gene            3437..4972
                     /gene="murJ"
                     /locus_tag="IT892_003331"
     CDS             3437..4972
                     /gene="murJ"
                     /locus_tag="IT892_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HAP3136514.1"
                     /translation="MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVA
                     FKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAVVTVAG
                     MLAAPWVIMVTAPGFADTADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIP
                     AFAPTLLNISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPHLKKIGMLVLPR
                     INFHDAGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPS
                     GVLGVALGTILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALPSAVALGILSGPLTV
                     SLFQYGKFTAFDALMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLI
                     LTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQKIFTPQPGWMAFLLRLVV
                     AVLVMSGVLLGMLHIMPEWSLGTMPWRLLRLMAVVLAGIAAYFAALAVLGFKVKEFAR
                     RTV"
     gene            complement(5012..5428)
                     /gene="flgN"
                     /locus_tag="IT892_003332"
     CDS             complement(5012..5428)
                     /gene="flgN"
                     /locus_tag="IT892_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FlgN"
                     /protein_id="HAP3136515.1"
                     /translation="MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITE
                     QKSSLLATLDYLEQLRRKEPNTANSVDISQRWQEITVKTQQLRQMNQHNGWLLEGQIE
                     RNQQALEMLKPHQEPTLYGANGQTSTTHRGGKKISI"
     gene            complement(5433..5726)
                     /gene="flgM"
                     /locus_tag="IT892_003333"
     CDS             complement(5433..5726)
                     /gene="flgM"
                     /locus_tag="IT892_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-28 factor FlgM"
                     /protein_id="HAP3136516.1"
                     /translation="MSIDRTSPLKPVSTVQPRETTDAPVTNSRAAKTTASTSTSVTLS
                     DAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN"
     gene            complement(5802..6461)
                     /gene="flgA"
                     /locus_tag="IT892_003334"
     CDS             complement(5802..6461)
                     /gene="flgA"
                     /locus_tag="IT892_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HAP3136517.1"
                     /translation="MLIIKRSVAIIAILFSPLSTASNLTSQLHNFFSAQLAGVSDEVR
                     VSIRTAPNLLPPCEQPLLSMSNNSRLWGNVNVLARCGNDKRYLQVNVQATGNYVVAAM
                     PIARGGKLEAGNVKLKRGRLDTLPPRTVLDINQLVDAISLRDLSPDQPIQLTQFRQAW
                     RVKAGQRVNVIASGDGFSANAEGQALNNAAVAQNARVRMVSGQVVSGVVDADGNILIN
                     L"
     gene            6616..7032
                     /gene="flgB"
                     /locus_tag="IT892_003335"
     CDS             6616..7032
                     /gene="flgB"
                     /locus_tag="IT892_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HAP3136518.1"
                     /translation="MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDID
                     FASELKKVMQRGRDATSVVALTMTSTQHIPAQALTPPTAELQYRIPDQPSLDGNTVDM
                     DRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN"
     gene            7036..7440
                     /gene="flgC"
                     /locus_tag="IT892_003336"
     CDS             7036..7440
                     /gene="flgC"
                     /locus_tag="IT892_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HAP3136519.1"
                     /translation="MALLNIFDIAGSALTAQSQRLNVAASNLANADSVTGPDGQPYRA
                     KQVVFQVNAAPGAATGGVKVADVIESQAPDKLVYEPGNPLADAKGYVKMPNVDVVGEM
                     VNTMSASRSYQANVEVLNTVKSMMLKTLTLGQ"
     gene            7452..8147
                     /gene="flgD"
                     /locus_tag="IT892_003337"
     CDS             7452..8147
                     /gene="flgD"
                     /locus_tag="IT892_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HAP3136520.1"
                     /translation="MSIAVTTTDPTNTGVSTTSSSSLTGSNAADLQSSFLTLLVAQLK
                     NQDPTNPMENNELTSQLAQISTVSGIEKLNTTLGSISGQIDNSQSLQASNLIGHGVMI
                     PGTTVLAGTGSEEGAVTTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVH
                     SFTWDGTLTDGSTAPNGSYNVAISASNGGTQLVAQPLQFALVQGVIRGNSGNTLDLGT
                     YGTTTLDEVRQII"
     gene            8172..9380
                     /locus_tag="IT892_003338"
     CDS             8172..9380
                     /locus_tag="IT892_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HAP3136521.1"
                     /translation="MAFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFA
                     GSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKL
                     DENRNLVNMQGLQLTGYPATGTPPTIQQGANPTNISIPNTLMAAKTTTTASMQINLNS
                     SDPLPTVTPFSASNADSYNKKGSVTVFDSQGNAHDMSVYFVKTGDNNWQVYTQDSSDP
                     NSIAKTATTLEFNANGTLVDGAMANNIATGAINGAEPATFSLSFLNSMQQNTGANNIV
                     ATTQNGYKPGDLVSYQINDDGTVVGNYSNEQTQLLGQIVLANFANNEGLASEGDNVWS
                     ATQSSGVALLGTAGTGNFGTLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQD
                     QILNTLVNLR"
     gene            9400..10155
                     /locus_tag="IT892_003339"
     CDS             9400..10155
                     /locus_tag="IT892_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgF"
                     /protein_id="HAP3136522.1"
                     /translation="MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAV
                     PVEGLSLPTRTLVTASTPGADMTPGKMDYTSRPLDVALQQDGWLAVQTADGSEGYTRN
                     GSIQVDPTGQLTIQGHPVIGEAGPIAVPEGAEITIAADGTISALNPGDPANTVAPVGR
                     LKLVKATGSEVQRGDDGIFRLSAETQATRGPVLQADPTLRVMSGVLEGSNVNAVAAMS
                     DMIASARRFEMQMKVISSVDDNAGRANQLLSMS"
     gene            10327..11109
                     /gene="flgG"
                     /locus_tag="IT892_003340"
     CDS             10327..11109
                     /gene="flgG"
                     /locus_tag="IT892_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HAP3136523.1"
                     /translation="MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDL
                     LYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGF
                     FQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
                     QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGY
                     VETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL"
     gene            11162..11860
                     /gene="flgH"
                     /locus_tag="IT892_003341"
     CDS             11162..11860
                     /gene="flgH"
                     /locus_tag="IT892_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HAP3136524.1"
                     /translation="MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPT
                     PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKT
                     NFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGN
                     LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN
                     MGWLQRFFLNLSPM"
     gene            11872..12969
                     /locus_tag="IT892_003342"
     CDS             11872..12969
                     /locus_tag="IT892_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415598.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HAP3136525.1"
                     /translation="MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVG
                     LDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQT
                     IDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
                     NGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDA
                     RTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVA
                     QGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRA
                     LNALGATPMDLMSILQSMQSAGCLRAKLEII"
     gene            12969..13910
                     /gene="flgJ"
                     /locus_tag="IT892_003343"
     CDS             12969..13910
                     /gene="flgJ"
                     /locus_tag="IT892_003343"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HAP3136526.1"
                     /translation="MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMF
                     VQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQ
                     PLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPA
                     QLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITT
                     TEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAG
                     YATDPHYARKLTNMIQQMKSISDKVSKTYSMNIDNLF"
     gene            13976..15619
                     /gene="flgK"
                     /locus_tag="IT892_003344"
     CDS             13976..15619
                     /gene="flgK"
                     /locus_tag="IT892_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HAP3136527.1"
                     /translation="MSSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMEQA
                     NSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTS
                     TSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNI
                     AIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVS
                     VQDGGTYNITMANGYSLVQGSTARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLN
                     TGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPA
                     VLQNTKNKGDVAIGATVTDASAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKV
                     AFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQ
                     ALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSIS
                     GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR"
     gene            15631..16584
                     /gene="flgL"
                     /locus_tag="IT892_003345"
     CDS             15631..16584
                     /gene="flgL"
                     /locus_tag="IT892_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-filament junction protein FlgL"
                     /protein_id="HAP3136528.1"
                     /translation="MRFSTQMMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPI
                     AASQAVVLSQAQAQNSQYTLARTFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTL
                     SDDDRASLATDIQGLRDQLLNLANTTDGNGRYIFAGYKTETAPFSEEKGKYVGGAESI
                     KQQVDASRSMVIGHTGDKIFDSITSNAVAEPDGSASETNLFAMLDSAIAALKTPVADS
                     EADKETAAAALDKTNRGLKNSLNNVLTVRAELGTQLNELESLDSLGSDRALGQTQQMS
                     DLVDVDWNATISSYIMQQTALQASYKAFTDMQGLSLFQLSK"
     gene            complement(16780..19965)
                     /gene="rne"
                     /locus_tag="IT892_003346"
     CDS             complement(16780..19965)
                     /gene="rne"
                     /locus_tag="IT892_003346"
                     /EC_number="3.1.26.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E"
                     /protein_id="HAP3136529.1"
                     /translation="MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKG
                     KITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIV
                     QIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL
                     PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAF
                     RDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIE
                     SAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQL
                     RLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRL
                     SPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASY
                     LLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEE
                     AMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKAAPATPVAPA
                     QPGLLSRFFGALKALFSGGEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRD
                     TRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTADEQQAPRRERSRR
                     RNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAV
                     VAPVVEETVAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEENNADNRDNGGMPRRS
                     RRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQV
                     EEQREQEEVHVQPMVTEVPVAAAIEPVVSAPVVEEVAGVVEAPVQVAEPQPEVVETTH
                     PEVIAAAVTEQPQVITESDVAVAQEVAEQAEPVVEPQEETADIEEVVETAEVVVAEPE
                     VVAQPAAPVVAEVAAEVETVAAVEPEVTVEHNHATAPMTRAPAPEYVPEAPRHSDWQR
                     PTFAFEGKGAAGGHTATHHASAAPARPQPVE"
BASE COUNT         4853 a         5278 c         5552 g         4801 t
ORIGIN      
        1 ataaaacaga caaatcaggg tgaaaagttg ttgcaggccg ctgaccatgc ccaccggcat
       61 catgcttaat gacattatca acagcccagc catcaaccgg tgttccagac gaaaatgctt
      121 ttcactccag cgggcgatag ggtagagcaa cgttaacgac agacacgctt caatggcata
      181 catccattta acggcagagg gcgcgccagc cacgtcgttg accataattg gcagcatcag
      241 catcacttgt acagccagca tgtagtaacc cgccagtgtc agaacatagg tgacaaaacg
      301 cttgtcacgc atcacgcggg tcatgccttc gcgaacgggc gtgcgtacgg tggagagttt
      361 ccatgctggt aacaaccacg cattgaacgc cgcacatagc acaaatagaa ctgcccctgt
      421 ggcgcagacc aggcgaaagt cgtattgcaa cagccagctc cccaacaatg cgccaatgac
      481 cgcaccggca ctgtcctgca tcatcaacag cgagaaaaaa cgaccacgct gctgtggacg
      541 gattaatttc accaccagcg ccgaacgcgg cggatcaaac aacgtgccac cgagtcccga
      601 gagcaggcat gaaaaccaca atagccacgg ttcgtgggcg atacccattg tggcgaatcc
      661 ggcggcgcgc atcagcatac cggtaacaat catcggtttg gcaccaaagc ggtcggcaat
      721 tgcaccgccg aaaataccca gaccttgctg aataaattgg cgtagaccga gagcaatacc
      781 gaccatgacg gcggcccagc ccatttgatc aacgaagcgg atagagatca gcgggaagac
      841 aacaaagaac cccagcacga ccagcatatt atcgatgagc aggaaatatt tacccaggtt
      901 cctcgcctgc gacacgcggg acatttcccc tcccgggaaa taaaagatga gcactttcta
      961 ttctgcattg ccgctaagac ttttcccatc acttcgggga caatattttt ttatcaaaac
     1021 gtcgctttga tagagagttt ttatcaaata tgtgaataat gcagaaaatg gcattttgga
     1081 cttttcacag ggtctggttg cgcaggtata gtaatactta cagcgtatta aagacgttac
     1141 gggaaggagt aggtatagaa tgtttggcta tcgcagtaac gtgccaaaag tgcgcttaac
     1201 cacagaccga ctggtcgtgc gtctggtgca tgatcgtgat gcctggcgtc ttgcggatta
     1261 ttacgcagag aatcgccatt tcctcaagcc ctgggagcca gtgcgcgacg aaagccactg
     1321 ttatccatca ggctggcagg ccaggctggg gatgattaac gaatttcata aacaaggttc
     1381 agctttctac tttggcttat tcgacccgga cgaaaaagag attattggcg ttgccaattt
     1441 ttccaatgtt gttcgtggct cttttcatgc ctgctatctc ggttattcga ttgggcaaaa
     1501 atggcagggc aaaggactca tgtttgaagc cctgaccgca gccattcgtt atatgcagcg
     1561 cacccaacat attcatcgca ttatggctaa ttatatgccg cacaataaac gcagcggtga
     1621 tttactggcg cgactgggtt ttgaaaaaga aggctatgcg aaagactatc tgttgattga
     1681 tggacaatgg cgcgatcacg tactgacggc attaactacc ccagactgga cgcccggccg
     1741 ctaaggagaa tctcatgaaa tatcaactta ctgcccttga agctcgcgtg attggttgct
     1801 tgctggaaaa gcaggtgacc acgccggagc aatacccgct ctcagtcaat ggtgtagtca
     1861 cggcctgtaa tcagaaaacg aaccgtgaac cggtcatgaa tctgagtgaa tccgaagtgc
     1921 aggaacagct ggataatctg gtcaaacgtc attatctacg cacagtgagc ggttttggta
     1981 atcgggtcac caaatatgag caacgttttt gtaattcaga atttggcgat ctgaaactga
     2041 gcgcagcgga agtggcgtta atcaccacgt tgttattgcg tggtgcccag acgccaggtg
     2101 aactgcgcag ccgcgccgcg cgaatgtatg aattcagcga tatggcggaa gtggagtcga
     2161 cgctggaaca actggcaaat cgcgaagatg gtccttttgt ggtgcgtctg gcccgcgaac
     2221 cgggtaaacg cgaaaaccgc tacatgcatc ttttcagtgg tgaggttgaa gatcagccgg
     2281 cggtgacgga tatgtcgaac gcggttgacg gtgatttaca ggcccgcgtc gaagccctgg
     2341 aaatcgaagt ggcagaactg aaacagcgtc ttgattcgtt gctggcccat ctgggagatt
     2401 aaagtgaaaa aattacgtat cggcgtagtg ggattaggtg gcattgcgca aaaagcgtgg
     2461 ttaccggtgc tggcggcagc gtctgactgg acgttacaag gagcctggtc gcctacgcgc
     2521 gcgaaagccc tgccaatttg tgaaagctgg cgcattcctt atgccgattc gttatccagc
     2581 cttgccgcca gttgcgatgc ggtttttgtg cattccagca ccgccagcca ctttgacgtg
     2641 gtcagtacgt tactcaatgc gggggtacat gtctgtgtcg ataaaccgct ggcagaaaat
     2701 ctgcgcgatg ctgaacggct ggtggaactg gcggcgcgga aaaaactgac gttgatggtc
     2761 ggttttaacc gtcgtttcgc accactctac ggtgagttaa aaacgcaact cgccaccgca
     2821 gcctcgctaa gaatggataa acatcgtagc aatagcgtcg ggccacacga tctttatttc
     2881 acgttgctgg atgattatct gcatgtggtg gataccgcgc tgtggttgtc gggcggcaaa
     2941 gcctctctgg atgacggtac gctactgact aacgacgctg gcgaaatgct gtttgccgag
     3001 caccattttt cggctggtcc tttgcagatc accacctgta tgcatcgccg tgccggaagt
     3061 cagcgtgaaa ccgtgcaggc cgtgactgac ggtgcgctca tcgacattac ggatatgcgc
     3121 gaatggcgtg aggagcgcgg gcagggcgta gtgcataaac cgattcctgg ttggcagagt
     3181 acgcttgagc aacgtgggtt tgtcggctgt gcgcggcact tcattgaatg tgtgcaaaac
     3241 cagacagttc cgcaaaccgc cggcgaacag gccgtgctgg cgcaacgtat cgttgacaag
     3301 atctggcgcg atgcgatgag tgaataaacc ctgtaacatc tggcggtagc aattcaccat
     3361 aatccaggta gactattcgc ctctttcagc gcctgccttg caggcgtttt gcccgtgggt
     3421 ctggattaga acaccgatga atttattaaa atcgctggcc gccgtcagct cgatgaccat
     3481 gttttcgcgt gtgcttggct tcgcacgaga cgcaattgtc gccagaatct ttggcgcagg
     3541 gatggcaacc gacgcctttt tcgtcgcttt taaacttcct aacttgttac gccgtatctt
     3601 tgccgaaggg gcattttccc aggcatttgt accgattctg gcggaatata aaagtaagca
     3661 gggtgaagac gccacgcggg tctttgtctc ttatgtttct ggcctgctga cacttgcgct
     3721 ggcggttgtg acggtcgctg gcatgctcgc cgcaccgtgg gtgatcatgg tgaccgcgcc
     3781 aggcttcgct gacacagctg acaaatttgc cctgaccagc cagctactaa agattacctt
     3841 tccctatatc ttgctgatct ccctggcgtc gctggtggga gcgattctga atacgtggaa
     3901 ccgcttctcg attccggcgt ttgctccaac actgcttaac atcagcatga ttggtttcgc
     3961 gctgtttgcc gcaccgtact ttaacccacc ggtgctggcg ctggcgtggg ctgttacggt
     4021 cggcggcgtc ctgcagctgg tgtatcagct accgcacctg aagaagatcg gcatgctggt
     4081 cctgccgcgc attaacttcc acgatgccgg agcaatgcgc gtggtgaaac agatgggacc
     4141 ggcgatcctt ggcgtctctg tgagccagat ctccttaatc atcaacacca tttttgcctc
     4201 gtttcttgct tccggttcgg tgtcttggat gtattacgcc gaccgcttaa tggagtttcc
     4261 gtccggtgtg ctgggcgtgg cgcttggcac cattttgctg ccgtcgctgt cgaaaagttt
     4321 tgccagtggc aatcatgatg aatacaaccg tttgatggac tgggggttgc gtctttgttt
     4381 cctgttggcg ctgccgagtg cggttgcgtt gggcattctt tccggtccgt tgaccgtttc
     4441 gctgttccag tacggtaaat ttaccgcgtt tgatgcgctg atgacccagc gggcgttaat
     4501 tgcctactcg gtgggtttga ttggcctgat tgtagtgaaa gtgttggctc ctggctttta
     4561 ttcccgccag gacattaaaa cgccagtgaa aattgccatc gttacgctga ttttaacgca
     4621 attgatgaac ctggcgttta ttggtccgtt gaaacatgcc gggctgtcac tttctattgg
     4681 tctggcggcg tgtctgaatg cttcgctgct ttactggcag ttgcgtaagc agaaaatctt
     4741 taccccgcaa cccggctgga tggcgtttct gttgcgtctg gtggtggcgg tactggtgat
     4801 gtctggcgtg cttttaggta tgttacatat catgccggag tggtcattgg gtaccatgcc
     4861 ctggcgttta ctgcgtttaa tggcggtcgt gctggcgggg attgccgcgt acttcgctgc
     4921 actggcggta ctgggcttca aagttaaaga atttgcccgc cggacggtgt aacaatgcat
     4981 tccggcctgc agtgcaggcc ggagataatc ttcagatcga aatcttttta ccgccgcgat
     5041 gggttgttga ggtctgaccg ttcgccccat atagcgtcgg ttcctgatgc ggtttcaaca
     5101 tttccagcgc ctgttgattg cgctcaatct gtccttccag taaccagccg ttatgttgat
     5161 tcatttggcg tagttgctgc gttttcacag taatttcctg ccagcgttga ctaatatcaa
     5221 cgctatttgc tgtattgggt tctttcctgc gtaactgttc gaggtaatcc agcgtcgcca
     5281 gcagtgagct tttttgttct gtaatccatt gcaactggct gccgttgatc tgccccatag
     5341 agagatgttg ctgctcttga tccattaccg ttttgagatc gttaagcaca gcggacatct
     5401 ggtcgaggat ctctgcaaga cgtgtcatac gatcagttac tctgcaagtc ttgctgcgct
     5461 tcgttgatca gcgcatcggc aattttgccg gtgtccattt ttagttcacc gttacgaatc
     5521 gccagtttta acgcttcgac acgttcaaga ttgatatcac tgctgccggg ttgcatcagt
     5581 tttgcttgcg cgtcgcttaa cgtcacactg gtgctggtgg aggcggttgt ttttgccgcc
     5641 cggctgttcg ttaccggcgc gtcagtggtt tcgcgcggtt gaacggtgct tacaggcttc
     5701 agaggcgaag tgcgatcaat actcatggtt tattcctcat tgagggcgct tttatcatgt
     5761 gttgcttatt tatcggcaag ggacgggtaa tctttaacag cttacaggtt tataagaata
     5821 ttcccatctg catcaacaac gccgctgact acctgtcccg ataccatgcg cacccgcgca
     5881 ttctgtgcga cggctgcatt gttcagcgcc tgaccttctg cgttggcgct aaacccatca
     5941 ccgctggcga tcacattgac gcgttgtccc gcttttaccc gccatgcctg gcgaaactgg
     6001 gttaactgga taggttgatc gggtgataga tcgcgcaggc taatggcatc aacaagttga
     6061 ttgatatcca gcaccgtacg cggtggcagg gtatccagcc gtccgcgttt cagtttgaca
     6121 ttgccagctt ccagctttcc tccccgcgca atgggcatcg cggcaaccac ataatttcct
     6181 gtggcctgta cattaacctg taaatatcgt ttgtcgttac cgcagcgtgc caacacattc
     6241 acattgcccc acaggcggga attattgctc atcgaaagca atggctgctc gcatggcggt
     6301 agtagattgg gcgctgtacg aatagaaaca cgaacctcat cacttacccc cgcgagttgg
     6361 gcgctaaaaa agttgtgcaa ttgcgatgtg agattgctcg ccgtacttaa cggactgaac
     6421 agtatcgcga tgatcgccac gctacgtttt attatcagca ttttcgcccc cagccatttc
     6481 tacaacgtga attgtacctg tccgcaatga ccatcaacgg cataaatagc gacccatttt
     6541 gcgtttattc cgccgataac gcgcgcgtaa aggcatttaa gctgatggca gaattttgat
     6601 acctgcggag gagatatgct cgataagctc gacgccgcct tacgttttca acaagaggcg
     6661 ctcaatctgc gcgcccagcg tcaggaagtg ctggcagcaa acatcgccaa tgccgatacc
     6721 cctggttatc aggcgcgcga tatcgatttt gccagtgaac ttaaaaaagt catgcaacgt
     6781 ggacgggatg caaccagtgt ggttgcactg acgatgacct caacgcaaca cattccggcg
     6841 caggcgctga cgcctcctac cgcagaactg caataccgta ttccggacca gccttcgctt
     6901 gacggtaata ccgtcgatat ggatcgcgaa cgcacccagt ttgccgataa cagcctgcaa
     6961 taccagatga gccttagcgc gttgagcggg caaatcaaag gcatgatgaa cgttttacag
     7021 agcggaaatt aacggatggc actgctgaat atttttgata tcgccgggtc ggcgttaact
     7081 gcccagtccc agcgcctgaa cgtggcggcc agtaatctgg cgaatgctga tagcgtgacc
     7141 ggtcccgatg gacagccata tcgggcaaaa caggtggtat tccaggttaa cgctgcacca
     7201 ggtgctgcga caggcggcgt aaaggttgcc gatgttatag aaagtcaggc cccggacaaa
     7261 ctggtttatg aaccgggtaa tccgctggca gatgcaaagg gctacgtaaa aatgccgaac
     7321 gttgatgttg tcggagagat ggttaacacc atgtcggcgt cacgcagcta tcaggccaat
     7381 gttgaagtgc tcaacacggt gaaaagcatg atgctgaaaa cccttacgct cggtcaataa
     7441 aggagaaagc tatgtccatt gcggtaacca ccaccgatcc gacaaatacc ggcgtcagta
     7501 ccaccagcag tagttcgctc acgggcagca acgccgcaga tttacaaagc agttttctga
     7561 ctttgctggt ggcgcagctg aaaaaccagg acccgaccaa tccaatggaa aacaacgagc
     7621 tgacgtcgca attggcacaa atcagcacgg tcagcgggat tgaaaaactc aataccacgc
     7681 tcggatctat ttccggacag attgataaca gccagtcgtt acaggccagt aacctgatcg
     7741 gtcacggcgt gatgatcccc ggcaccactg ttcttgcggg aaccggcagt gaagaagggg
     7801 ctgtgaccac gaccacgccg tttggtgttg agctgcaaca ggcggcagac aaagttacgg
     7861 ccaccatcac cgataaaaat ggcgcggttg tgcgcaccat tgatattggt gaactgaccg
     7921 ccggagttca cagtttcacc tgggacggta cgttgactga tggcagcact gcgccgaacg
     7981 gttcttacaa tgtagcgatt agcgccagta acggtggtac acaactggtt gcccagccgc
     8041 tgcagtttgc tctggtgcag ggtgtgatcc gcggcaacag cggtaatacg ctggatctcg
     8101 gcacttacgg caccaccacc ctcgacgaag tacggcagat aatttaagcc ttcacatttc
     8161 aggagtcagt catggccttt tctcaagcgg ttagcggatt aaacgctgcc gccaccaacc
     8221 tcgatgttat tggcaacaat atcgccaact ccgccaccta cggctttaaa tcaggcacgg
     8281 cctcttttgc cgatatgttt gccggttcga aagtgggact gggggtaaaa gttgccggta
     8341 tcactcagga ctttaccgat ggcacgacca ccaacaccgg gcgaggtctg gacgttgcta
     8401 tcagccagaa cggttttttc cgtctggtag acagcaacgg ttcggtgttc tacagccgta
     8461 acggacaatt taagctggat gaaaaccgta acctggtgaa tatgcaaggt ttacagctga
     8521 cgggttaccc ggcaaccggt acgccgccga ctattcagca aggggcgaat ccgaccaata
     8581 tttcgatccc gaataccctg atggcagcga aaactaccac cacggcatcg atgcagatca
     8641 acctgaattc cagtgatccg cttcctactg ttacgccatt cagcgccagc aatgcggata
     8701 gctataacaa aaaaggttcg gtgactgttt tcgacagtca gggtaatgct catgacatga
     8761 gcgtctactt tgtgaagacc ggggataata actggcaggt ctacacccag gatagcagtg
     8821 atccaaacag cattgcgaag acagcgacaa cactggaatt taatgctaat ggcacattag
     8881 tggatggtgc gatggcgaat aatatcgcaa ccggcgcaat taacggtgca gaacccgcca
     8941 cgtttagtct gagcttcctc aactccatgc agcaaaatac cggcgctaac aatattgtgg
     9001 caaccaccca gaacggctac aaaccgggcg atctggtgag ttatcaaatc aatgatgacg
     9061 gtacggttgt cggcaactat tccaacgaac aaacccaact gctggggcag attgtactgg
     9121 cgaactttgc caacaacgaa ggtctggcat ccgaaggcga caacgtctgg tctgcgacgc
     9181 aatcttctgg cgtggcgctg ttggggacag ccgggacggg aaactttggc accctgacca
     9241 acggtgcgct ggaagcgtcc aacgtcgatc tcagtaaaga actggtcaat atgatcgttg
     9301 cccagcgtaa ctatcagtct aacgcccaga ccatcaaaac ccaggaccag atcctcaaca
     9361 cgctggttaa cttacgctaa tcgctgacgg gatagctcaa tggatcacgc aatttatacc
     9421 gcgatgggag cagccagcca gacactgaat caacaggcgg taaccgccag taatctggcc
     9481 aatgcctcaa cgcccggttt tcgcgcgcag ttgaatgctt tacgcgcggt gccagtggaa
     9541 gggctttctc tgcctacgcg cacgttggtc acggcgtcaa cgccgggcgc agatatgacg
     9601 cccggcaaaa tggattacac ctcgcgcccg ctggacgtcg cgttgcagca ggatggctgg
     9661 ctggccgtgc agaccgctga cggcagcgaa gggtatacgc gtaatggcag cattcaggtt
     9721 gatcccaccg ggcaactgac aattcagggg catccggtga taggcgaggc tgggccaatt
     9781 gctgtgccgg aaggggcgga aatcactatt gctgccgatg gcacaatctc ggcgctcaat
     9841 ccgggcgatc cggcaaatac ggttgcgcca gtagggcgtc ttaaactggt gaaagccacg
     9901 ggcagcgaag tgcagcgcgg tgacgacggc atttttcgtt taagcgcaga aacccaggcc
     9961 acgcgtgggc cggtactgca ggcagatcca accttgcgtg tgatgtcggg ggttctggaa
    10021 ggcagtaacg tcaatgccgt tgcggcaatg agcgacatga ttgccagcgc gcggcgtttt
    10081 gaaatgcaga tgaaggtgat cagcagcgtc gatgataacg caggccgtgc caaccaactg
    10141 ctgtcgatga gttaattgaa aggatacatg acaagtataa gttgcccgat gcgcaagttt
    10201 atcgggtcta tgggggcaat cgcaatttat cgattttgcg agcacttgta ggccggataa
    10261 ggcgtttacg ccgcatccgg caagaagaca tatgcacttt gtcactaatc cactacagga
    10321 cattttatga tcagttcatt atggatcgcc aaaacgggcc ttgacgccca gcaaaccaat
    10381 atggacgtca ttgccaacaa cctggcaaac gtcagtacta acggttttaa gcgtcagcgc
    10441 gcggtgtttg aagatctgct ttatcaaacc attcgccagc cgggggcaca gtcttccgaa
    10501 caaaccacct taccctccgg attacaaatc ggcacggggg tacgcccggt cgccactgaa
    10561 cgcttacaca gccagggaaa cctgtcgcag accaacaaca gcaaagatgt cgcgattaaa
    10621 gggcagggct ttttccaggt gatgttgcca gatggttcat cagcctatac ccgtgacggc
    10681 tctttccagg tggatcagaa cgggcagctg gtgacggctg gtggttttca ggtgcagcca
    10741 gcgatcacca ttccggcgaa tgcgttaagt atcaccatcg gtcgtgatgg cgtggtcagc
    10801 gtaacccaac aaggccaggc agctccggtt caggttgggc agctcaatct caccaccttt
    10861 atgaatgaca ccgggctgga gagcattggc gaaaacctct acaccgaaac gcaatcctct
    10921 ggtgcaccga acgaaagcac gccgggcctg aacggcgcgg gactgctgta tcaagggtat
    10981 gttgaaacgt ctaacgtcaa cgtggcggaa gaactggtca atatgattca ggtgcaacgc
    11041 gcttacgaaa tcaacagtaa agcggtgtcc accaccgatc agatgctgca aaaactgacg
    11101 caactctaag gcttaaccgg tggcaggttc accggtttac tgatttttga agatgatagc
    11161 catgcaaaaa aacgctgcgc atacttatgc catttccagc ttgttggtgc tttcactaac
    11221 cggctgcgcc tggataccct ccacgccgct ggtgcagggg gcgaccagtg cacaaccggt
    11281 tcccggtccg acgcccgtcg ccaacggttc tattttccag tctgctcagc cgattaacta
    11341 tggctatcaa ccgctgtttg aagatcgtcg accacgcaat attggcgata cgctgaccat
    11401 cgtgttgcag gagaacgtca gcgccagcaa aagctcctct gcgaatgcca gccgtgacgg
    11461 taaaactaat tttggctttg atactgtgcc gcgctatttg caggggctgt ttggtaacgc
    11521 tcgtgccgat gtcgaagcct ccggtggtaa cacgttcaac ggaaagggcg gggccaatgc
    11581 cagcaatacc tttagcggca cgttgacggt gacggttgac caggtactgg tcaacggcaa
    11641 cctgcatgtg gtgggtgaaa aacagattgc cattaatcag ggtaccgaat ttattcgctt
    11701 ctctggcgtg gttaatccac gcactatcag cggcagcaat accgtaccgt ctactcaggt
    11761 ggcggatgcg cgcattgaat acgtaggcaa tggctacatt aacgaagcgc aaaatatggg
    11821 ctggttgcag cgtttcttcc ttaacctgtc gccaatgtaa gtgaggctgt ggtgattaaa
    11881 tttctctctg cattaattct tctactggtc acgacggcgg ctcaggctga gcgtattcgc
    11941 gatctcacca gtgttcaggg ggtaaggcaa aactcactga ttggctatgg tctggtggtg
    12001 gggctggatg gcaccggtga ccagacaacc cagacgccgt ttaccacaca aacgcttaat
    12061 aacatgctct cacagctggg aattaccgtt ccgacgggca ccaatatgca gctaaaaaac
    12121 gtcgctgcgg taatggtgac agcgtcactt cctccgtttg gacgtcaggg gcaaaccatc
    12181 gatgtggtgg tttcttccat gggaaatgcc aaaagcttgc gtggaggtac gttgttgatg
    12241 acaccgctta agggcgttga cagtcaggtg tatgcgctgg cgcagggcaa tattctggtt
    12301 ggcggcgcag gagcctccgc tggcggtagc agtgttcagg ttaaccaact gaacggtgga
    12361 cggatcacca atggtgcggt tattgaacgt gaattgccca gccagtttgg cgtcgggaat
    12421 acccttaatt tgcaacttaa cgacgaagat ttcagcatgg cgcagcaaat cgctgacacc
    12481 atcaaccgcg tgcgtggata tggcagcgcc accgcgttag atgcgcggac tattcaggtg
    12541 cgcgtaccga gtggcaacag ttcccaggtc cgcttccttg ccgatattca gaatatgcag
    12601 gttaatgtca ccccgcagga cgctaaagta gtgattaact cgcgcaccgg ttcggtggtg
    12661 atgaatcgcg aagtgaccct cgacagctgc gcggtagcgc aggggaatct ctcagtaaca
    12721 gttaatcgtc aggccaatgt cagccagcca gatacaccgt ttggtggtgg acagactgtg
    12781 gttactccac aaacgcagat cgatttacgc cagagcggcg gttcgctgca aagcgtacgt
    12841 tccagcgcca gcctcaataa cgtggtgcgc gcgctcaatg cgctgggcgc tacgccgatg
    12901 gatctgatgt ccatactgca atcaatgcaa agtgcgggat gtctgcgggc aaaactggaa
    12961 atcatctgat gatcagcgac agcaaactac tggcaagtgc ggcctgggat gcgcaatcac
    13021 tcaacgaact aaaggcgaaa gcgggcgaag atccggcggc aaatatccgt ccggtggccc
    13081 gtcaggtgga agggatgttc gtgcagatga tgttgaaaag catgcgcgac gctttaccaa
    13141 aagatggcct gttcagcagc gagcacactc gcctgtatac cagtatgtat gaccagcaga
    13201 ttgcccaaca gatgacggcg ggcaaaggtc tggggcttgc agagatgatg gttaaacaga
    13261 tgacgccaga acaaccattg ccagaggagt ccacgccagc agcaccgatg aaattcccgc
    13321 tcgaaactgt ggtgcgttat caaaatcagg cgctttcgca gctggtgcaa aaggccgtgc
    13381 cacgtaacta cgatgattcg ctgccgggtg acagtaaagc attcctcgcg caactctcgc
    13441 tgcccgccca actggcaagc cagcaaagcg gtgtgccaca tcatttgatc ctcgctcagg
    13501 cggcactgga atctggttgg gggcaacggc aaatccgccg cgaaaacggc gagccgagct
    13561 ataacctgtt tggtgtcaaa gcctctggca actggaaagg gccagttact gaaatcacca
    13621 cgactgaata tgaaaacggc gaagcgaaga aagtaaaagc gaagtttcgc gtctacagct
    13681 cgtatctgga agccttgtcg gattacgttg ggctgttaac gcgtaacccg cgctacgccg
    13741 ccgtgacgac cgccgcgagt gcggaacagg gggcgcaggc cctacaggac gcgggctatg
    13801 ccaccgatcc tcactatgcc cgcaaactca ccaacatgat tcagcagatg aaatcgataa
    13861 gcgacaaggt gagcaaaacc tacagtatga acattgataa tctgttctga ataactcaag
    13921 tccggcgggt cgctgccgat aatactctgt aattgaaggc ttataaggaa cctccatgtc
    13981 cagcttgatt aataacgcca tgagcggact gaacgcggcc caggcggcgt taaatacggc
    14041 aagtaataat atctccagct ataacgttgc cggatatacc cgccaaacca ctattatgga
    14101 gcaggccaat agcacgttgg gcgctggcgg ctgggttggc aatggtgtct acgtttctgg
    14161 tgtgcagcgt gagtatgatg cgtttattac caaccagtta cgtgcggcgc agacgcaaag
    14221 tagcggtctg actgcccgct atgagcagat gtcgaaaatc gacaatatgc tctccaccag
    14281 tacctcttcg ctggcaacac agatgcagga tttcttcacc agcctgcaaa cgctggtgag
    14341 taacgcggaa gacccggcag cgcgccaggc gctgattggg aaatcagaag gattggtgaa
    14401 tcagtttaaa accaccgatc aatatctgcg cgaccaggac aaacaggtca atatcgcgat
    14461 aggtgccagc gttgatcaga tcaacaacta cgctaaacaa attgccagcc tgaacgatca
    14521 aatctcgcgc ctgacaggcg tgggggcagg ggcgtcacct aacaatctgc tggatcaacg
    14581 cgatcaactg gtgagcgaat taaaccagat tgttggtgta gaagtcagcg ttcaggatgg
    14641 cggcacttat aacatcacga tggccaatgg ttactcactg gttcagggaa gtacggcgcg
    14701 gcaactggcg gcagttcctt ccagcgctga cccttctcgt acgactgtcg cttatgttga
    14761 tgggacggca ggcaatattg agatcccgga gaaattactg aataccgggt cgctgggcgg
    14821 cattctgaca ttccgttctc aggatctgga ccagacgcgt aatacgcttg gacaactggc
    14881 gctggcattt gccgaggctt tcaacaccca acacaaagcc ggatttgatg ctaacggcga
    14941 tgccggtgaa gatttctttg ctatcggtaa gcccgcggtt ctgcaaaaca cgaaaaacaa
    15001 aggtgacgtt gcgatcggtg ccacggtaac tgatgcctcc gcggtactgg cgacagatta
    15061 caaaatctcg ttcgataata atcagtggca ggtcacccgc cttgccagca ataccacttt
    15121 tacggtgacg ccggatgcca acggtaaagt ggcatttgat ggtctggagt tgacgtttac
    15181 aggaacgcct gccgttaacg acagcttcac gctgaaacca gtaagtgacg ccatcgtcaa
    15241 catggatgta ttaatcaccg acgaagcgaa aatagcgatg gcgagcgaag aagatgcggg
    15301 tgatagcgat aaccgcaacg gtcaggccct gctggatctg caaagcaaca gtaaaacggt
    15361 gggcggtgcg aaatccttta acgacgctta tgcctcgtta gtgagtgata tcggtaataa
    15421 aaccgcgacg ttgaaaacca gtagcgccac gcaaggtaat gtggtgacgc agctttccaa
    15481 tcagcagcag tcgatttccg gtgtcaatct cgatgaggag tacggaaatc tgcaacgttt
    15541 tcagcagtat tacctggcga atgcgcaggt tctgcagacg gcaaacgcga tttttgatgc
    15601 gctgattaac attcgctaag gggagataag atgcgtttca gtacacagat gatgtaccag
    15661 caaaacatgc gtggtatcac caattctcag gcagaatgga tgaagtacgg cgaacagatg
    15721 tcgacgggta agcgagtcgt taacccttct gacgatccca ttgctgcatc acaagccgta
    15781 gttctctccc aggcacaggc gcaaaacagc cagtacacgc tggcgcgtac tttcgccact
    15841 caaaaagtgt cactggaaga gagtgtactt agccaggtca ccactgctat ccagaatgct
    15901 caggaaaaaa ttgtctacgc cagcaatggc accttgagtg acgatgaccg ggcctcgctg
    15961 gctacggata ttcaggggct tcgtgaccag ttgctgaatc tggcaaacac cactgacggt
    16021 aacgggcgct acatttttgc cggttataaa acagagactg cgccgtttag cgaagagaaa
    16081 gggaaatacg tcggtggagc agaaagtatt aaacaacagg tcgatgcttc gcgttcgatg
    16141 gtgatagggc acacgggtga caaaattttc gacagtatta ccagcaacgc ggtagcggaa
    16201 ccagacggta gcgcttctga aaccaatctt tttgccatgc tggatagtgc catcgcagcc
    16261 ctgaaaacgc cggtcgcgga tagcgaagcg gataaagaaa ccgccgctgc ggcgttagat
    16321 aaaaccaacc gcggactgaa aaactcgctg aacaatgtgc tgactgttcg cgcggaatta
    16381 ggcacgcagc tgaacgaact ggagtcgctg gattcattag gtagcgatcg cgctttaggg
    16441 caaacgcagc agatgagcga tctggttgat gtggactgga atgcaactat ttcatcttac
    16501 atcatgcagc aaacggcatt gcaggcatcg tataaagcat ttaccgatat gcagggattg
    16561 tcgctcttcc agctcagcaa ataatttcgc tttaaaacat atcatgaaac tgggtatgtt
    16621 ttgtctgcct gctctgggat cgctggggcg ggcatttttt tgcctatttt gcattgttgg
    16681 ttagcaagga tgccattcga tgaattttaa tatgttgatt caaagatgaa ataaaaaagc
    16741 cctggcagtt accagggctt gattactttg agctaattat tactcaacag gttgcggacg
    16801 cgcaggagcg gcagaggcat gatgtgttgc cgtatgacca cctgcggcac ctttaccttc
    16861 gaaggcaaaa gtagggcgct gccagtcact gtgacgcggt gcctccggaa catattccgg
    16921 tgctggagcg cgcgtcattg gcgcggtagc gtggttatgc tcaacggtga cctcaggttc
    16981 gaccgcagct accgtttcaa cttctgctgc gacttcagcg actactggcg cggcaggttg
    17041 agcaacaact tcaggttcag caactacaac ctcagcagtt tcgacaactt cttcaatatc
    17101 tgccgtctct tcctgcggtt caaccaccgg ttctgcttgt tctgcaactt cctgggctac
    17161 ggcaacatca gactcggtaa tcacctgcgg ctgttcagtt accgcggcag cgatcacttc
    17221 aggatgcgtc gtttcaacca cttccggttg cggttcggca acctgaacgg gggcttctac
    17281 gacaccggcc acttcttcaa caactggcgc gctaacaacc ggttcgatag cggcggcgac
    17341 agggacctca gtcaccatcg gctgcacatg tacttcttcc tgttcgcgct gctcttcaac
    17401 ctgtacatct tgcggacgta caattggata gcggatccag actttgccag aggccagttc
    17461 cggagacgcg cacgctacgg tcaacggcat tggcgactgg gttggataac gctcgtcacg
    17521 atagcgacga cgacgctgac cacttacgcg caggtgacga ggcgagcggc gagaacgacg
    17581 cggcatgcca ccgttgtcac ggttatcagc attgttctct tcttgctgtt ctggtgcagt
    17641 ttgcgctacg actggcagcg ggactttcac cagttctgtg cgtggagctg gcgcttcctg
    17701 aacaattggt tcggcagcga cagtttcttc aaccaccggt gcgactaccg cttcttcggc
    17761 tacgctttgc tcgtaacgca ctttctgatt gagctgacgc tgtttacgac gcggctgaac
    17821 cggacgtaca cgttcttcct gttcggtttc ctgaacagat tgctcttcaa cattcagcgc
    17881 cttcgcttct tgttgcgcct gacgtttatc atcattacgg cggcggctac gttcacgacg
    17941 cggcgcttgc tgctcgtcgg cggtacgcgc tttttccgtt acctcagcct gctgacggct
    18001 ctcacgcgtc tcggcagtct gctgctgtgc ctggcgacga ttacgacggt tttcttcgcg
    18061 attatcgctg ccttcagtac gttcactacg ggtgtcgcgg cgctcattac ggtcacggcg
    18121 gttgttctga cgaggcttgc gacgatcctg ttgacgttcc ggtttcgctt ctgctttcgg
    18181 tgctggttgc tcggtcggtt tggtttcttc accaccgctg aacagcgctt tcagtgcgcc
    18241 gaagaagcgg ctcaacagcc caggttgtgc aggagctact ggtgttgccg gtgcagcttt
    18301 cggtgctgga gctacaacag gcgcggcagg ttcagctggc gttggcgcag gcggcacatc
    18361 cggcatggca aaggttgcca gcgcaggttg ttccggacgc ttacgttcag cgaactcttc
    18421 ttcagacggc agcgccatcg cttcttcatg cagcttcggc agcatgtagc ttaaggttgg
    18481 ggtttcttcc cctttacgca cgcgcagcac gtggtagtgc ggggtttcca tctgatcgtt
    18541 tggcacaatt acacagcgca caccgtcctg acgagtttca atggcattta ccgcagaacg
    18601 tttttcattc agcaggtaag aagcgattgg cacaggaaca atggcgtgaa cttcctgggt
    18661 gttctctttc agcgcttctt cttcgatcag acgcagaata gagagcgaca gcgattcgtt
    18721 gtcacgcacg gtgccagtac cagaacaacg cggacaaacg tgatgactgg attcacccag
    18781 tgatgggctc aggcgctgac gggacatttc cagcaggcca aagcgagaaa tatggctgat
    18841 ttgaatacgc gcacggtcct gacgcaccgc ttcacgcaga cggttttcta ccgcacgctg
    18901 gtggcgtact ggcgtcatgt cgatgaagtc gataacaatc aggccgccga ggtcacgcag
    18961 gcgcagctga cgagcaatct catcggcagc ttcgaggtta gtgttaaacg cggtttcttc
    19021 gatatcgccg ccgcgggtcg cgcgtgcgga gttgatgtcg atggccgtta acgcttcggt
    19081 gctgtcgata acaatggaac caccagacgg cagacgaact tcacgctgga aggcggactc
    19141 gatctgtgac tcgatctggt agtggctgaa cagcgggatc tcgccggtgt acagtttgat
    19201 tttgctgctg aaatccgggc gacctaatgc agcgatatgc tgacgtgcca gttcgagcac
    19261 tttcgggtta tcgataagga tttcgccgat gtcctgacgt aagtaatcgc ggaatgcgcg
    19321 aacgattacg ttgctctcct gatgaatcag gaacggggcc gggcggcttt cagcggcttt
    19381 tttgatggct tcccagtgtt tcagacggaa gcttaaatcc cattgcagcg cctcagcaga
    19441 tttgccgacg ccagcggtgc gcacgataag ccccatgcct tccggcagtt caaggcttgc
    19501 cagtgcttct tttaattcgg tacggtcgtc gccttcgata cggcgagaaa tgccacccgc
    19561 gcgcgggttg ttcggcatca gaaccagata gctacccgcc agactgataa aggtggttaa
    19621 tgccgcgcct ttgttgccgc gctcttcttt atcgatctga acaatgactt cctgaccttc
    19681 acgcaacaca tctttaatgt tgggacgacc atgagcactg tagttagcag ggaaatattc
    19741 gcgggcaatt tcttttagtg ggaggaaacc gtgacgttca gcgccgtaat caacaaaagc
    19801 agcttccaga ctcggttcaa tgcgggtgat tttacctttg tagatgtttg cctttttctg
    19861 ctcgtgccct ggactttcga tatccaggtc atacagacgc tgcccatcta caagggcaac
    19921 gcgcaactct tcctgctgag ttgcgttgat taacattctt ttcatcgtaa cttactcatt
    19981 attcttacat tgacgactaa gctgcgggca aagtaacgcc tttccgggtg tgaaccgatg
    20041 gcctcgtgtc tagtcgcgtc gccaacctca cggttatcgt cagctcaaag aggcgcagag
    20101 tgtcggttgc ccgtttttca tgcggaaaaa cagcgcaatt atcaaagaaa cagactgggt
    20161 attactctcc agaaatattt ccatctaccg gtaaggactg caacccgcag cccgctaact
    20221 gcctgaaaga tcaatacgtc ttacgccatt gctgcgtgga tgatcggtcg ggcaaaatgg
    20281 gttattccgt aaaatttctt gttttaacaa ggatggacac ggaaacggcc tcattattcc
    20341 actgcaagcc ttgttatagc aagatgactt ttaccattta tcacccgctt actcacagtt
    20401 ttttcacttc ttgctggtga ttggtttaat aaccatcaat aaagtgatca cgcagtgaag
    20461 taataaggtg caaaagtaaa tata
//
LOCUS       DACAOP010000085        20330 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.085, whole genome shotgun sequence.
ACCESSION   DACAOP010000085 DACAOP010000000
VERSION     DACAOP010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20330
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.085"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            126..644
                     /locus_tag="IT892_003347"
     CDS             126..644
                     /locus_tag="IT892_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HAP3136530.1"
                     /translation="MALPRKLKYLNMFNDGLSYMGVVESVTLPKLTRKLEKYRGGGMP
                     GAVSVDLGLDDDALSLEWTLGGLPDIELWAQYASPGADSVPLRFTGSYQRDDTGAISA
                     VEVVMRGRHKEYDGGENKQGESGTTKMATECAYYQLTIDGKEVIEIDVINMVLKVDGV
                     DRMAEHRKVIGL"
     gene            699..1013
                     /locus_tag="IT892_003348"
     CDS             699..1013
                     /locus_tag="IT892_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HAP3136531.1"
                     /translation="MKNINETAVADTENVNPNVVIFDTPLMRGEQKVEQVTLTKPNAG
                     TLRGVSLASLANSDVDALIKVLPRMTYPALTEHELARLDASDLISLAGKVVGFLSPAS
                     GR"
     gene            1046..1168
                     /locus_tag="IT892_003349"
     CDS             1046..1168
                     /locus_tag="IT892_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HAP3136532.1"
                     /translation="MADIAVIFHWPPSELNSLSVTELLTWRDKALQRSGSHHEQ"
     gene            1158..3599
                     /locus_tag="IT892_003350"
     CDS             1158..3599
                     /locus_tag="IT892_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAP3136533.1"
                     /translation="MSNNVRIEVLLNAVDRASRPLKAIQNASKSLSGDIRNSQKSLCE
                     LNVQASRIDGFRKASAQLAVTGHSLEKAKQEAQALATQFKNTERPTRAQAQVLESAKR
                     AANGLQTKYNSLTESVKRQQRELGAVGINTRNLANDERGLKSRISETTAQLNRQREAL
                     AKVSAQQAKLSRVKARYQAGKSLAGNAAAAGAAGVGIATAGTLAGVKLLTPGYEFAQK
                     NSELQAVLGVDKQSPEMQALRKQARQLGDNTAASADDAAGAQIIIAKSGGDAAAIQAA
                     TPVTLNMALSNKRTMEENAALLTGMKSAFQLSNDKVAHIGDVLSMTMNKTAADFDGMS
                     DALTYAAPVAKNAGVSIEETAAMVGALHDSKITGSMAGTGSRAVLSRLQAPTGKAYDA
                     IKELGIKTSDSKGNTRPIFSILKEMQRSFEKNNLGTGQKSEYMKTIFGEEASSAAAVL
                     MAAASSGKLDQLTAAFKASDGKTEELVKVMQDNLGGDFKEFQSAYEAVGTDLFDQQEG
                     SLRKLTQTATQYVLRLDGWIQKNKGLATTLGVVVGGALALIGVMGGIGLVAWPVVMGI
                     NAIIAAAGVLGVVFSTVGGAIVTAIGAISLPVLAVAGAVVAGALLIRKYWEPLGAFFS
                     GVVEGLKAAFAPVGDMFTPLAPVFDAIAEKLGVVCQWFKDLLAPVKATQDTLSSCKNV
                     GVTFGQALADALMMPLKMFNSLSGKVGWLLEKLGVIKKESSDLDQTAAKANKASPNGG
                     YIPATAGYGGYQAYQPVTAPAGLSYIDQSKSEYNINLQGGVAPGSDLDRQLRDAVDKL
                     DREKRARQRSSMRLD"
     gene            3613..4077
                     /locus_tag="IT892_003351"
     CDS             3613..4077
                     /locus_tag="IT892_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP3136534.1"
                     /translation="MLMGLGFFVFERRTLPHQSMQYSKDYRWVSNDRIGKPPAYQYLG
                     EGETSRTLSGTLYPEITGGRLSLMAIELMADEGRAWPLIDGTGMIHGMYVIDKVTHNH
                     TELFSDGAAKKIEFSLSLKRVDESLAAIYGDLKTQADNLVTSAGNWLGGLAG"
     gene            4074..5237
                     /locus_tag="IT892_003352"
     CDS             4074..5237
                     /locus_tag="IT892_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001461187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HAP3136535.1"
                     /translation="MITGMTIQAGARIAPDFMLTLGGADITQNFSDRLIGLTMTDNRG
                     FEADQLDIELDDTDGLVELPPRGASLTLWLGWQGSALINKGSFTVDEIEHRGAPDRLT
                     IRGRSADFRGTLNSRREQSWHDTTLGVIVETIAQRNKLTASVADTLKAVAVPHIDQSQ
                     ESDAAFLSRLADRNGATVSVKAGKLLFLKAGSAMTASGKAIPQMTVERGDGDRHQFAI
                     ADREAYSGVTAKWLHTRDPKPQKQKVKLKRKPKEQHLRALQHPKVAKTSAKAKKKKVQ
                     EAREGEYMAGESDNVLELTTIYATKAQAMRAAQAKWDRIQRGVAEFSITLATGRADLF
                     PETPVAVKGFKRVIDEQAWIISRVVHSLNGSGFTTGLELEVKVSDVEYESEEV"
     gene            5318..5539
                     /locus_tag="IT892_003353"
     CDS             5318..5539
                     /locus_tag="IT892_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HAP3136536.1"
                     /translation="MFHCPKCHHAAHARTSRYFTDTTKERYHQCTNINCSCTFVTTET
                     VERFIVSPGEVVPAPPHPTSSGQQQIHWM"
     gene            5846..6697
                     /locus_tag="IT892_003354"
     CDS             5846..6697
                     /locus_tag="IT892_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like serine protease"
                     /protein_id="HAP3136537.1"
                     /translation="MNNIPISTQWTLDATGEVGRSSVNSVYMIICPATGSKGSGFLID
                     NGLIVTNEHVITGCSTNQIFAISAYGQKIPISQKWIDSDRDLAVLRPAITQTGGLSIV
                     KDNDLKVGESVTTWGYPLGYNGPAPLLSVGYLAGFNSYQTAKGQKKHLVVNGAFNSGN
                     SGGALLKASDNKVIGIVVSKHAPISQYHQSAIEALSENMSGVTYTATNDAGETKSFVE
                     SQIVAELLIHMRSLTQVMIGEAIAAEELLSMLSEIDLSPPQSMSRNALCHCGSGKRFK
                     ECHGKIS"
     gene            complement(7107..8468)
                     /locus_tag="IT892_003355"
     CDS             complement(7107..8468)
                     /locus_tag="IT892_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HAP3136538.1"
                     /translation="MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFN
                     HENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIM
                     LVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
                     IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKY
                     EPIPVQNVEPTLGIGAPTDKVFMIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVE
                     RLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGY
                     TEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELM
                     TPQGNINFTLEHMENAKGEAMPVAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNP
                     HGK"
     gene            complement(8615..8947)
                     /locus_tag="IT892_003356"
     CDS             complement(8615..8947)
                     /locus_tag="IT892_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HAP3136539.1"
                     /translation="MAGWFELSKSSDNQYRFVLKAGNGETILTSELYTSKASAEKGIA
                     SVRSNSPQEERYEKKTASNGKFYFNLKAANHQIIGSSQMYATAQSRETGIASVKANGT
                     SQTVKDNT"
     gene            complement(9138..9860)
                     /gene="baeR"
                     /locus_tag="IT892_003357"
     CDS             complement(9138..9860)
                     /gene="baeR"
                     /locus_tag="IT892_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BaeR"
                     /protein_id="HAP3136540.1"
                     /translation="MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGD
                     QVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEI
                     GADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
                     LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAE
                     QSFIRAVYGVGYRWEADACRIV"
     gene            complement(9857..11260)
                     /gene="baeS"
                     /locus_tag="IT892_003358"
     CDS             complement(9857..11260)
                     /gene="baeS"
                     /locus_tag="IT892_003358"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     BaeS"
                     /protein_id="HAP3136541.1"
                     /translation="MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIK
                     HGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQILRSFEHDNSEDKPGPGMPPHG
                     WRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFD
                     KQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSED
                     ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPE
                     TVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLEVAGGAFRERFASRG
                     LKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLQISAGQRDKTVRLTFAD
                     SAPGVSDDQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGG
                     VSITVELPLERDLQREV"
     gene            complement(11257..12672)
                     /locus_tag="IT892_003359"
     CDS             complement(11257..12672)
                     /locus_tag="IT892_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136542.1"
                     /translation="MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESP
                     LHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELL
                     LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEY
                     ASWHWIFLINIPVGIIGAIATLLLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSK
                     GTGLSPLTIAGLVAVGVVALVLYLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIG
                     SGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATT
                     LGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNS
                     LLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMALIIALPAFIF
                     ARVPNDTHQNVAISRRKRSAQ"
     gene            complement(12673..15750)
                     /gene="mdtC"
                     /locus_tag="IT892_003360"
     CDS             complement(12673..15750)
                     /gene="mdtC"
                     /locus_tag="IT892_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtC"
                     /protein_id="HAP3136543.1"
                     /translation="MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPV
                     IMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDIN
                     GAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST
                     QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAVSNANVRKPQG
                     ALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTN
                     AKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEV
                     EQTLIISVALVILVVFLFLRSGRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMAL
                     TIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSISLSLVAVFLPLL
                     LMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRML
                     VALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQA
                     DQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQ
                     QIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRK
                     KLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIY
                     QPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGL
                     SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILI
                     IAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI
                     GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSG
                     GDGSELRHPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE"
     gene            complement(15751..18873)
                     /gene="mdtB"
                     /locus_tag="IT892_003361"
     CDS             complement(15751..18873)
                     /gene="mdtB"
                     /locus_tag="IT892_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtB"
                     /protein_id="HAP3136544.1"
                     /translation="MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVS
                     ALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITL
                     QFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM
                     TQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAIT
                     GANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAE
                     NSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTT
                     NIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFS
                     INNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFS
                     LIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQN
                     RFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQD
                     NGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQ
                     INLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQAT
                     SLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNA
                     LYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKI
                     EQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGST
                     LAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGS
                     ELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTT
                     LAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK
                     SRFARHEEEA"
     gene            complement(18873..20120)
                     /gene="mdtA"
                     /locus_tag="IT892_003362"
     CDS             complement(18873..20120)
                     /gene="mdtA"
                     /locus_tag="IT892_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter subunit MdtA"
                     /protein_id="HAP3136545.1"
                     /translation="MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPGATKQAQ
                     QSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTIIAANTVTVRSRVDGQLMALH
                     FQEGQQVKAGDLLAEIDPSQFKVALAQTQGQLAKDKATLANARRDLARYQQLAKTNLV
                     SRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQIS
                     SGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTL
                     LSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNE
                     GHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVE
                     AQSATTPEEKATSREYAKKGARS"
BASE COUNT         4854 a         5411 c         5607 g         4458 t
ORIGIN      
        1 aactgtatat cgattacgac tatacccccg tcccgccgct ggaaaacctg accctgcgcc
       61 agcgcatcac cgatacctat ctggcgaacc tgtcggactc ggtcaacagc taaggagctc
      121 tgagcatggc gttaccccgc aaactgaaat acctgaatat gttcaacgat ggcctcagct
      181 atatgggcgt tgttgaatcc gtcaccctgc caaaactgac ccgcaagctg gagaaatatc
      241 gcggcggcgg gatgccgggg gcggtgtcgg ttgaccttgg cctcgatgac gatgcgctgt
      301 cgcttgagtg gacgctcggc ggtctgcctg acattgaatt gtgggcgcag tacgcctcac
      361 cgggtgctga cagcgtgccg ctgcgtttta ccggctctta tcagcgtgac gacaccggcg
      421 cgatttctgc cgtcgaggtg gtgatgcgtg gccgtcataa agaatacgac ggcggtgaaa
      481 acaagcaggg cgaaagcggt acaaccaaaa tggcgaccga gtgcgcctat taccagctca
      541 cgatcgacgg caaagaagtc atcgagattg acgtgatcaa catggtgctg aaagtcgacg
      601 gtgtcgaccg tatggcagag caccgcaagg tgattggcct gtaatccttc aaccggtcag
      661 tgaggctggc cggtcattta ccctgatgag aaattcgcat gaaaaatatc aatgagactg
      721 ctgttgctga cactgagaac gtcaatccga atgtcgttat ttttgacacc ccgctgatgc
      781 gcggtgagca gaaagttgag caggtcacct taaccaaacc gaatgcggga accctgcgcg
      841 gggtgtcgct ggcgtcgctg gcaaattccg acgttgatgc gctgattaag gtgctgccgc
      901 gcatgacata tccggcactg accgagcacg agctcgcgcg tctggatgcg tcagacctga
      961 tttcactggc cggtaaggtg gtcggttttt tgtcaccagc ttcgggtcgc tgaccttccc
     1021 ggaaaaactg tcggtcgatg acctgatggc ggatattgcg gtgatcttcc actggccgcc
     1081 atcagagcta aattccctga gtgtgaccga gctcctgaca tggcgcgata aggcgctgca
     1141 acgaagcgga agccatcatg agcaataacg tcagaatcga ggtgctgctg aacgcagttg
     1201 accgggcaag ccgcccgctt aaagcgattc agaacgccag caaatccctg tctggtgata
     1261 tccgcaattc acaaaaaagc ctgtgcgaac ttaatgtgca ggcgtcccgt attgacggat
     1321 tccgcaaagc cagcgcccag cttgccgtga ccggtcattc gcttgagaaa gcgaaacagg
     1381 aagcgcaagc ccttgccaca caatttaaaa acaccgagcg cccgacgcgc gcgcaggcgc
     1441 aggtgcttga atcggcaaag cgtgccgcca acgggctgca gacgaaatac aacagcctca
     1501 ctgagtctgt taagcgccag caacgtgaac tcggtgcagt cggtattaat acccgtaatc
     1561 tggcaaatga tgagcggggg cttaaatcgc gcatcagtga gactaccgcg cagcttaatc
     1621 ggcagcgtga ggcactggcg aaagtcagcg cacagcaggc gaagttaagc cgggtgaaag
     1681 cgcggtatca ggccggtaaa tcactggccg gaaacgcggc ggcggctggc gcagccggtg
     1741 ttggtattgc gacggcggga accctcgccg gggttaagct gctgacgcct ggttatgaat
     1801 ttgcacagaa aaactcagag ctgcaggccg tgctcggtgt cgacaaacag tcgcctgaaa
     1861 tgcaggcgct gcgtaaacag gcgcgccagc tcggtgataa taccgctgcc tctgccgatg
     1921 atgcggcggg tgcgcagatt atcattgcca aaagcggcgg cgatgcggcg gccattcagg
     1981 cggcgacgcc ggtcacactg aatatggcgc tgtcgaacaa gcgcacgatg gaagaaaacg
     2041 ctgcgctgct gacaggcatg aaatctgctt ttcagctctc taacgataaa gtcgcgcata
     2101 ttggtgatgt tctctcgatg acgatgaaca aaaccgccgc cgactttgat ggaatgagtg
     2161 atgcgctgac ctatgccgcg ccagtggcga aaaatgccgg ggtaagtatc gaagaaaccg
     2221 ccgcaatggt gggggcgcta cacgattcca aaatcaccgg ctcgatggcg ggtacaggga
     2281 gtcgtgccgt tctgagtcgc ctgcaggcgc caaccggtaa agcgtacgac gccatcaaag
     2341 agctcggtat taaaacgtca gatagcaaag gcaatacgcg cccgatattt tccatcctga
     2401 aagaaatgca gcgcagtttt gagaaaaaca atctcggaac gggtcagaaa tccgaataca
     2461 tgaaaaccat tttcggtgaa gaggccagct cggcggccgc cgtgctgatg gccgccgcat
     2521 caagcggcaa gctcgaccag ctcaccgccg cgtttaaagc ctcagacggt aagactgagg
     2581 aactggttaa ggttatgcag gataacctcg gcggcgactt taaagagttt cagtcagcct
     2641 atgaggcggt cggcactgac ctgtttgatc agcaggaggg ctcactgcgt aagctgacgc
     2701 agacggccac gcaatatgtg ctcaggctcg acggctggat ccagaaaaat aaagggctgg
     2761 cgaccaccct cggcgtggtg gttggtggtg cgctggcgct gatcggtgtg atgggcggga
     2821 ttggccttgt cgcatggccg gtggtgatgg ggattaatgc catcattgcg gcggctggcg
     2881 tgctcggtgt ggttttcagt acggtcggcg gcgcgattgt cacggccatt ggcgcaatca
     2941 gcctgccggt gctggcggta gccggtgcag tggtggccgg tgcattgctg atccgcaaat
     3001 actgggagcc gctcggtgca ttcttctcgg gcgtggtgga gggactgaaa gccgcctttg
     3061 caccggtggg ggacatgttt accccgctcg cgccggtgtt tgacgccatc gctgaaaagc
     3121 tgggtgtcgt ctgccagtgg tttaaagacc tgcttgcgcc ggtgaaagcc acgcaggaca
     3181 cgctctccag ttgcaaaaat gtcggcgtta cttttggtca ggcgctggct gatgcgctga
     3241 tgatgccgct caagatgttt aacagcctga gcggcaaggt cggctggctg ctggagaaac
     3301 tcggcgttat caaaaaagaa tccagcgacc tcgaccagac cgcagcgaaa gcgaataagg
     3361 cgtccccgaa tggcgggtat atccctgcga ccgcaggtta tggcgggtat caggcgtatc
     3421 agccggtcac agcgcccgca ggcctgtctt atatcgacca gagcaaaagc gaatacaaca
     3481 tcaacctgca gggcggagtc gcaccgggca gtgaccttga ccgccagctc cgtgacgcgg
     3541 tcgacaaact tgaccgcgag aaacgtgcgc gtcagcgatc cagtatgaga ctcgactgag
     3601 ggagggataa aaatgttaat ggggctgggc tttttcgtgt ttgaacggcg caccctgccg
     3661 catcagtcaa tgcagtattc gaaggactac cgctgggtgt caaatgaccg tatcggaaaa
     3721 cccccggctt atcagtatct cggggagggg gaaacctcgc gtaccctgtc gggcacgctt
     3781 taccctgaaa tcaccggcgg gcgtctgtca ctgatggcca tcgaactgat ggccgatgag
     3841 gggcgcgcat ggccgctgat tgacggaacc ggcatgatcc acgggatgta tgtcatcgat
     3901 aaagtgactc acaaccacac cgagttattc agcgacggcg cggctaaaaa aatcgagttt
     3961 agcctgtcgc ttaagcgggt ggatgaatcc ctcgcggcca tctacggcga cctgaaaacg
     4021 caggctgata atctggtcac gtctgccggt aactggctcg gggggctggc gggatgataa
     4081 cgggaatgac tattcaggcc ggggcgcgca ttgctcctga ttttatgctc acgctcggtg
     4141 gcgcagatat cacacagaat ttcagcgacc ggcttatcgg gctgaccatg accgacaatc
     4201 gcggattcga ggctgaccag cttgatatcg agctcgatga taccgatgga ctggtcgagc
     4261 tgccgccgcg cggggcatcg ctgaccctgt ggctgggctg gcagggctcg gcgctgatta
     4321 acaaagggag ttttacggtt gacgaaatcg agcaccgggg cgcgcctgac aggctgacta
     4381 tccggggacg cagtgcggat tttcgcggga cgctgaactc gcgccgcgag cagtcatggc
     4441 acgacaccac gctcggggtg attgtcgaga ctatcgcgca gcgtaacaaa ctgacggcca
     4501 gcgtggctga taccctgaaa gctgttgctg tgccgcatat tgaccagtct caggaatccg
     4561 acgcggcgtt tttgtcccga ctggcggatc gcaacggggc aacggtttcg gtcaaggccg
     4621 ggaaattgtt attcctgaaa gccggtagcg cgatgacggc cagtggtaag gccatcccgc
     4681 aaatgaccgt cgaacgcggc gacggcgacc ggcatcagtt tgccatagcc gaccgcgagg
     4741 catactccgg cgtaaccgct aaatggctgc acaccagaga cccgaaaccg caaaagcaaa
     4801 aggtgaagct caagcgcaaa cccaaagagc agcacctgcg tgcgctgcag cacccgaagg
     4861 ttgctaaaac atcggcaaag gctaaaaaga agaaggtgca ggaagcgcgg gaaggtgagt
     4921 atatggccgg tgagtccgac aatgttctgg aactcacgac catctacgcg acaaaggcgc
     4981 aggccatgcg cgcagctcag gcaaagtggg acaggataca gcgtggggtg gcggagtttt
     5041 cgatcacgct cgccactggc cgcgctgatt tatttcctga aacgccggtg gcagtgaaag
     5101 gctttaagcg cgttatagac gagcaggcgt ggataatcag tcgtgtggta cacagcctca
     5161 acgggagcgg cttcacgacg ggcttagagc ttgaggttaa ggtttctgat gtggagtatg
     5221 aaagcgagga agtttaacgg cgtgtgttgt ttatgtgttt gttttataag taaaaattag
     5281 taaaattaac acattgaata cgccggagac cctcatcatg tttcattgtc cgaaatgcca
     5341 tcatgccgcc cacgcccgca cgagtcgcta ttttactgat accacaaaag agcggtatca
     5401 ccagtgcaca aacattaact gcagctgcac gtttgtgacc actgaaacag tcgagcgttt
     5461 tatcgtgtcg ccgggggaag tagtacccgc gccgccgcat ccgacatcat caggtcagca
     5521 acaaattcac tggatgtgac aaacgagaaa gccccgcgaa tgcggggctt tttgcaactt
     5581 ttagatcagt tatgttaagt acatttccgt cggcaaagtg ccaggagcgg gttctagaga
     5641 gtgactaacg ttagttatat gtgtaaaatt ccttaaaaat aagaaggata tatatccatg
     5701 acagcaattg catattggat taactgagaa tcaattgaga aatttttggg ggggcaaaaa
     5761 ataaactagc taattaaatt tttataaata acgaatataa gactgcaagc catttaacaa
     5821 aagtttataa ataaaggagt cagttctgaa caatatcccc atatctactc aatggacttt
     5881 agacgctacg ggtgaagttg gacgctcatc agtaaattct gtttatatga ttatatgtcc
     5941 tgcgaccggc tcgaaaggat ctggtttttt aatagataat gggttaatag taacgaacga
     6001 gcatgttatc actggatgct ctacaaatca gattttcgca atttcagctt atggacagaa
     6061 gattccaatt tctcaaaaat ggatagattc tgatcgcgat ttagctgtgc tgagacctgc
     6121 cattacccag actggtgggc taagtattgt taaggataat gatcttaaag ttggtgaatc
     6181 agtaacaact tggggatacc cattaggata caacggtcct gcaccgttac tatccgttgg
     6241 ttatctagca ggatttaact cataccaaac cgccaaggga caaaaaaaac atctagtggt
     6301 aaatggggca tttaactcag gaaattctgg tggagctctt ttaaaagctt cagataataa
     6361 agtaataggt attgtagtga gtaagcatgc tcctatcagt caataccatc aatcagctat
     6421 tgaagctttg tctgaaaata tgagtggcgt cacctatacc gctactaatg acgctggaga
     6481 aactaaaagt tttgtagaat ctcaaattgt agcagaatta ttgattcata tgagaagtct
     6541 aactcaagtt atgattggag aagcaattgc agcagaggaa ttactttcga tgcttagcga
     6601 aattgacttg agtccaccac aatctatgtc aagaaatgcc ttatgtcatt gcgggagtgg
     6661 aaaacgcttc aaagaatgtc atggaaagat atcctagtaa gtacttatat cagtctgata
     6721 atggctcttc aaatacaaaa gacttcactt actctgccgt catctctgct cctcgcttat
     6781 tgcagacggt caaaagctta caagctgttg actagatgtg ttcttacatt gtcagttaaa
     6841 acaaaagccc cgcaaatgcg gggctttttg tatcgatgtg gtcaatgtgt ggacattgat
     6901 agaaataaat ccatttattt cagtaattta catgcaaaaa ataagcccgt gtaagggaga
     6961 ttacacaggc taaggaggtg gttcctggta cagctagcat tttatgggtt atgtttttca
     7021 gcgaaacgga tgataacctt aataaatgca gctgtatgtg atcggtttct aagaattttc
     7081 catccgggaa aaataatcga aattaatcac ttaccgtgtg ggttacgcgt ggtttccccg
     7141 gagaaattac gcatcagcag agcgtaattg agctcaagat cctgcgggac cgggagccac
     7201 acagtataac catcgcctgg tgcgaccggc atcgcttcac ctttggcgtt ttccatgtgc
     7261 tcaagggtaa agttaatgtt gccttgcggc gtcatcagct caaggctgtc gccaacggag
     7321 aatttatttt tcaccgctac cgccgcgagg tcccccttgc gctcaccggt aaactcacca
     7381 acaaactgct ggcggtcaga aactgaataa ccgtattcgt agttctgata atcgtcgtga
     7441 gtatgacgac gcaggaaacc ttcggtatag ccacgatgcg ccagaccttc cagagtttcc
     7501 agcaggctgg tatcgaacgg tttgcccgca gcggcgtcat cgatagcttt acggtaaacc
     7561 tgtgcggtgc gtgcgcaata gtagaaagat ttagtacggc cttcgatttt cagcgaatgc
     7621 acgcccattt tggtcaggcg ttctacatgg gcgatggcgc gcagatcttt cgagttcatg
     7681 atgtaagtgc cgtgctcatc ttcaaacgcg gtcatatact cgcccggacg ctgggcttct
     7741 tcgatcataa acactttgtc ggttggcgcg ccgataccca gcgtcggctc aacattttgc
     7801 accggaatcg gctcgtactt gtgtacgatg ttgccaacgt catcttcttt cccttcctgg
     7861 acgttgtact cccagcggca ggcgttggtg caggtaccct ggttcggatc gcgcttgttg
     7921 atatagccag agagcaggca gcgaccggag taggccatgc acagtgcgcc gtgaacgaag
     7981 atctcgatct ccatatccgg cacctgattg cggatctctt caatctcttc cagcgacagc
     8041 tcgcgagaga ggatcacgcg ggtcaggccc atttgctgcc agaatttcac cgtcgcccag
     8101 tttacggcgt tagcctgcac cgagaggtgg atcggcattt cagggaagtg ctcacgcacc
     8161 agcataatca gccctggatc ggacataatc agcgcatccg gccccatttc caccaccggt
     8221 ttcaggtcac ggataaaggt tttcagcttg gcgttgtgcg gtgcaatgtt gaccacgaca
     8281 taaaactttt tccccagcgc gtgggcttca ttgatgccga gctgaagatt ttcgtggttg
     8341 aattcgttgt tgcgcacacg cagggagtaa cgcggctggc ccgcataaac agcatctgcg
     8401 ccataagcga aagcgtaacg catatttttc agcgttcccg ccggggaaag gagttccggt
     8461 ttaaacataa ttctctcgtt ctgatgacag gtcagatccg cttcacctga tgaagcggtt
     8521 aggggagtgc ccccacttta agggcgggca ttgtagcgct gtggggggat ctggtaaagc
     8581 gccggacgcc aacaacccac gcccggcatc gtaattacgt attgtctttc accgtctggc
     8641 ttgtgccatt ggctttaacg gaggcaattc cggtttcacg agattgcgcg gtggcgtaca
     8701 tctggctgga gccgataatt tgatgattag cggctttcag attgaaatag aatttgccgt
     8761 tacttgccgt ttttttctca tagcgttctt cttgcgggct gttgctacgc accgacgcga
     8821 tgcccttttc cgcagaggct tttgaggtat aaagctcgct ggtgaggata gtctcaccat
     8881 tgcccgcttt tagcacaaac cggtactgat tatcactgct cttactgagt tcaaaccaac
     8941 cagccataat gactccttga ttgaaattgt gtatcgaaaa cagcatctaa aggtgctgtt
     9001 taccgattaa agtatgagcg attttctgat gcctgccagg gcggagagat aatgtcagtt
     9061 tgctgaccat gcgtgggata atgttgccgg atctggtctg aacgccatct ccggctaaca
     9121 aaataatgtc gctaaaacta aacgatgcgg caggcgtcgg cttcccagcg gtaaccgacg
     9181 ccataaacgg cgcggataaa tgactgttcg gcgtcgagag attccagctt gcggcgcagg
     9241 tttttaatgt ggctgtcgat ggtgcggtcg gttactacgc ggtagtcgtc ataaagatga
     9301 ttgagcaatt gctcgcggga gaacactttt cctggttcgt gagagagcgt tttcagcaga
     9361 cgaaattccg caggcgtcag gtcaagcatt ttaccgcgcc atgaagcctg aaaacgacct
     9421 tcgtcgataa tcaacgggct ttcagcatcc tgttgctgca actcgcgctg cggtttgcaa
     9481 cggcgcaaaa tggttttgac gcgcgctacc acttcccgtg ggctgtacgg cttacagata
     9541 taatcatctg cgccaatctc cagccccagc aggcgatcga tctcttcgat ttttgccgtc
     9601 accatcacga tcggaatgtc agaaaaacga cgaatttccc ggcacagcgt caggccatcg
     9661 gtgccaggga gcatcagatc taacaggatc agatccggtg gtgtctggcg cacatacggc
     9721 agtacctgat cgccgtggct gataagcgtc ggcgcatagc tcgcagcacg cagataatca
     9781 atgagcaact gccccagctt cggttcatct tccacgatca aaatacgcgg tgtgttttcg
     9841 tcgattggta actcggtcat acttctctct gtaaatcccg ttccagcggt aactctactg
     9901 taatgcttac cccgccaaaa ggcgaatggg cagcaataat gcgaccatta tgtgcttcaa
     9961 caatgttcag gcaaatcgcc agccccagcc cggaaccgcc gctggcacgg ttgcgggaac
    10021 cttcggtgcg ataaaaacgt tcaaacaatt tttgtagctg atcgtcactg acacctggcg
    10081 cactgtcggc aaaggtcagg cgcaccgttt tgtcgcgctg cccggcagag atttgcaggc
    10141 tgccgccgct gtcagtgtag cgcaggctgt tttccagtaa gttattgaat aactgcatta
    10201 aacggtcgcg atcgccaaat acggtaatac tgtctggcag ggaaaattgc agtttcaggc
    10261 cacgactggc gaatcgttcg cgaaatgcgc cgcccgccac ttccagcagt gggatcaaat
    10321 ctaccggtgc tttttgatag gcgagagcgc cttcatcaga catcgacaac tgatggagat
    10381 cgtcaaccag tttggtcagt gtaccgacct ccgcctgtaa agacgccacc gtctccggcg
    10441 tgaatttacg cacgccatcc tgaatggctt ccagttcacc gcgcagcacc gctaatggcg
    10501 tacgcagttc gtgagaaata tcggccataa aatcgcgccg catttgctgg tttttctcca
    10561 gtgtgctggc aagctggttg aagtcttgcg ccagtttgcc cagttcatct tcactggtgg
    10621 gcgttacgcg ggtagtgaaa tcgcccgccg ccagtttgtg cgtgccatcg acaagtcgtt
    10681 ttaccggtgc cagtaaaccg cgcgccagca gaaaagtggc aagtgccgcg agtaacgttg
    10741 ccagggcgac aatcaaccag ctggtttgcc gctgttgttt atcgaaattg atatcagtat
    10801 tgcgcgttaa ccgctcaacg ggggaggcga tcaccgcgcc aacttccgca ccgttgacca
    10861 gaatgggtcg ccgtgtaccg tcaggtggaa tcggcgctcg cggaccaacc agcactttgt
    10921 tgttttgatc aaccacccag aactgggtac gccagccgtg cggtggcata cccgggccgg
    10981 gtttatcttc cgaattatcg tgttcaaatg aacgcaggat ctgaaagaca aagcgatcat
    11041 tgttgcgcag gaagcgccag ttgccatgct gcgcatactg ctcgccaagc gcatcactta
    11101 acagttgtaa tcgctgttca ttaccatgct tgatgtaatc aataaagcca cgctcaaaac
    11161 tgatacgcac cgcccagtgc atactgatca gcaagacaat gcaggtggcg aaaatcgcca
    11221 gaaacagttt gccggtaata ccgggtcgcc agaacttcat tgcgcgctcc tttttcgccg
    11281 cgaaatagct acattttgat gcgtatcgtt cggcactctg gcaaagatga acgccggaag
    11341 ggcgatgatc aacgccatgc taagccaggt gtacataaag acggtttgtg tggtgccgct
    11401 gtcgacgctg acatgctgtg aaccaaaaag tcccagcaac agcccggcga tagtgacgcc
    11461 gatactcatc gacaattgca taatcatcga cagcaggctg ttgccgctgc tcgccagatt
    11521 gtccgggaga tctttcagcg tcagggtgtt catggaggag aaacgcgtcg agttgaccat
    11581 cccttgtaaa aacaggacga acggcaaaac gtagtaccag cccagcaggg cggtagtcat
    11641 aaacaacagg gtgaccagcg acagacccag cgtggtcgct accagtaccc gacgataacc
    11701 aaagcgattc accacctgta ccacaattcg cttcattccc atgctgccaa gcaccatcgg
    11761 gatcatcatc agtccggcat gaaacggcga gaaaccgagg ccaatttgca ggaaaaccgg
    11821 tgtcataaag ggcaacatgc cactgccaat acgtccggca aagctccccg ccaggcccag
    11881 cgaaaaggta cgagtacgga acagtttcag actgaacagg gcacggttgt tatttctggc
    11941 gtgcagcaga taaagcacca gtgccaccac gccaactgcg accaggcctg caatcgtcag
    12001 cggcgataaa cctgtacctt tactgccgtc cagcgccagg gttaataccg ccatgccaac
    12061 cgccagcaat aaaaatccgg agagatcaaa gcgccgcgtc tgcatggtgt agtttggcat
    12121 taacagcaat gtggcgatcg caccgataat ccccaccgga atgttgatca aaaagatcca
    12181 gtgccacgat gcgtactcca ccagcagacc gccgagcgcc ggaccgagca gcggaccgac
    12241 ctgaccgggt aacgtgacaa aggtcatcgc cgccatatat tgctcgcgcg gtacgatttt
    12301 catcaccgtc aatctgccga ccggcaccat catcgcgccg ccaacgccct gtaacgcgcg
    12361 tgccagcaac agttcgttca gcgtgccgga aagcgcgcaa aacagtgaac cgagagtaaa
    12421 cagcacgatg gcggtaaaga aaatattgcg cacgccgact ttgtccgcca gccagccgct
    12481 ggcgggcagc atcaccgcca cggtcagcac ataagagaca atgaccatgt gcatatgcaa
    12541 cggactttcc ccgaggcttt gcgccattga gggaagggcg gtgtttacga tggtggtgtc
    12601 cagcgactgc ataaagaagc cgaaagccac aatccacaat tgccaacggg tgctgtcggg
    12661 aagatctgtc atttactcgg ttaccgtttg tttaggttta cgcgaaaaac gcagccgcag
    12721 acggtcgaaa aagagataca ccaccggcgt ggtatacagc gtaaggagct ggctcattac
    12781 cagtccgccg acaatggtga tccccagggg gtgccgcagc tccgagccgt cgccgcccga
    12841 caataccagc ggcagcgcac caaacagcgc cgccagggta gtcatcataa tcgggcgaaa
    12901 acgcagcaga caggcctgga aaatagcttc ctgcggcgtc aggttaccgt gccgttgggc
    12961 ttcaagcgca aaatcgacca tcataatggc gtttttcttc acgatgccga ttaatagcat
    13021 gatccctatc agggcgatta ggctgaacgg ggcattgaac agctccagcg ccaacagcgc
    13081 tccaacgccc gccgagggca gggtggagag aatcgtcagc ggatgtacgt aactctcgta
    13141 aaggataccc agcacgatat acaccgtggc gatggcggcg ataatcagga tcacctgcga
    13201 gttcatcgtc tcctggaaca cctgcgccgt gccggcaaaa ctgccgcgca ccgtcgaagg
    13261 cacaccaagc tgggtcattg cgcgatcgat cgccgcactg gcgtccgaga gcgattttcc
    13321 ggtcggcagg ttaaacgaaa tggtcgaggc cgccgataat ccctgatgat tcaccgatag
    13381 tggggcattc gccggttgcc atttagcgaa atacgacagc gggatcgctt tgccttcgtt
    13441 attgataacg aacatttttt ccagcgcact gatgtcctgg gtatagcgcg gatccacttc
    13501 catcaccact ttatactggt tcatcggctg gtaaatggtc gagatttgcc gctgaccgaa
    13561 ggcgttattt aacagactgt tggcggcttg tacgtcgatt cccagccgtg ccatggtgtc
    13621 gcggtcgtaa accagattca tctccgcgcc gttatcctgc tgatcggagt tcacgtccgc
    13681 cagttccggc aacgtcgcca gttttttgcg gattttcggc tcccattctc gcagtgccgc
    13741 caggtcgtcg gataacaacg tgtactggta gctggcgttc gactgacgcc caccaacgcg
    13801 aatatcctgt accgccatca ggaacagatt cgcccccggt tctttcgcca gttttacgcg
    13861 cagacggtcg ataatttgct gcgccgtttc gctgcgttcg tcgcgtggct tgagggtgat
    13921 aaacatcatc ccgctgttca ctcgcgaacc gcctgtaaag ccggtgacat tatccactgc
    13981 cggatcgtca cggataattt tcatgaaatc ctgcaactta ccgcgcatcg cctgaaacga
    14041 aatactctga tccgcctgaa tcccgcccat caacacgcca gtgtcctgct ccgggaagaa
    14101 ggttttcggg atcgagatat acagccagat attcagcgca atggtgccaa gcagcaccac
    14161 gcccaccaga cgggtatgat tgagcaccca tttcagtgac ttgccgtagc cttgttgcag
    14221 ggctaccaac atgcgaccaa aaccacgcag tcgcttttgc tcgcgcggct tgctggcttt
    14281 cagcatccag ccacacatca ttggcgttaa tgtcagagaa accagcaacg atataccaat
    14341 ggcgacagaa agcgtcacgg caaattcgcg taacagtcgg cccggcaatc cgcccatcaa
    14401 cagcagcggc aggaacaccg ccaccagtga cagacttatc gacagcaccg taaaaccgac
    14461 ttcgcgagta ccttgcagtg cggcttgcaa cggtttcatt cccgcttcca gatgacgtgc
    14521 aatgttttcc agcaccacga tggcgtcatc caccacgaaa ccagtagcga tggtgagcgc
    14581 cattaacgaa aggttattga gactgaatcc gcacaggtac atcgccgcaa acgtaccaat
    14641 cagcgaaacc ggcaccgaaa cggcgggaat aatagtggcg cgacccgagc gcaggaataa
    14701 aaacaccacc agaatcacca gcgccaccga gataatcagc gtttgctcga cttcttccag
    14761 cgaggcgcga atggtggggg agcgatcctg ggcaatttgc agatcaatcg ccgccggaat
    14821 ggtttcctgc aactccggta attttgcccg gatgctgtca accgtctgga taatattggc
    14881 ttccggcagt ttgcggatca tcagtaaaat agccggtttg gcgttggtca tcccggcgtt
    14941 gcgcacatcc tgcactgagt cggtcaccgt cgccacatcg cccagacgaa ccgcgccgcc
    15001 gttgttgtag tgaataatca acggctgata ttcagcggcg gtttttagct catcattggt
    15061 ctggatctgc cagcggtgag tgccatcttc cagcgcgccc tgcggtttac gcacgttggc
    15121 attgctgacg gcggtgcgta cgtcgtccag cgacacgccc tgattaaaca gcgcctgcgg
    15181 attcagcccg acgcgtacgg cgggcagtga gctgcctccg acatcgacat caccaacacc
    15241 gtcgatttgc gaaatcgtcg gagccagctg cgtcgaggcg aaatcgtaca gttcaccctg
    15301 cgaataagta tcggacgtca gcgtgaggat cataattggc gcatccgacg ggttcgcttt
    15361 gcgataggtc gggcggctgg gcatcccact gggcagcaaa ctttgtgcag cgttgatcgc
    15421 cgcctgcaca tcacgcgctg cgccgttgat atcccggtca aaatcaaact gcaaaataat
    15481 acgcgtgctg ccgagcgaac tgctggaggt catttcactg actccggcaa tgcgcccaag
    15541 tgagcgctcc agcggcgtgg caacggaaga tgccattgtt tctggtgacg caccgggcag
    15601 cgaggcgctg accataatca ccggaaaatc gacctgcggc agcggggcga ccggcagcat
    15661 acggaagccc agtatgccgc acagggtaat ggcaaccgac agtaaaatcg tcgccaccgg
    15721 acggtaaatg aagagggcaa aaaacttcac ttacgcctcc tcttcatgac gggcaaagcg
    15781 gcttttggtc cacaatgcca ggcggtcgaa cagcagataa atcaccggcg tggtgaacag
    15841 cgtcagcacc tggctgacaa tcaggccgcc gaccatgccg atacctaacg gacgacgcag
    15901 ttccgcaccg accccggtac tcaacatcag cggcagcgcg ccaagcagag ccgccagggt
    15961 ggtcatcagg atcggacgaa aacgcaacag acaagcctgg tagattgcct cgcgcggcga
    16021 catgccttgc tcgcgctcgg cagccagcgc gaagtcgatc atcatgatgg cgttcttctt
    16081 cacgataccg atcagcaaaa taatgccgat aatcgcaatc acatccagtt cgctaccagc
    16141 aatcagcaac gccagcagtg cgccaacccc tgcggtgggt agcgtcgaga gaatggtgat
    16201 cgggtgaata aagctctcgt acagaatgcc gagcacgata tacatcgcca ccaccgccgc
    16261 gacaatcagc cagacagtgc tgcccagcgc cgactggaag gcgagggtgc tgccctggaa
    16321 ctgcgtggtg atatccaccg gcagattcag cgtcttttcg gtgtccataa tcgcctgcac
    16381 cgcatcgccc agcgaatagt tatccggcac gttaaaggag atggtcgtta ccgggaactg
    16441 atccagatgg ttgatggaga gcggcgcaaa acgctgctca attttggcaa ttgagcttag
    16501 cggcaccacg ccgccgtcgc tgctggtcag gcgaatggta tccagcgccg cgaggcctgg
    16561 ggtattttcg gtgttgtgct ccagcaccac gcgatactgg ttggcctgag tataaatagt
    16621 ggaaatcagc cgctgaccaa acgcgttgta cagggcgtta tcgacatccg ccatgctgat
    16681 ccccagacgg ctggcgctgt cgcgatcaac attgacatac gccaccagcc ctttgtcctg
    16741 ccagtcgctg gagacatcag aaagctgtgg cagttgctgg agtttttcca tcaactgtgg
    16801 cacccaggta ctgagcgcat ccagtgacgt ggcctgcaag gtaaactggt actgggtgcg
    16861 gctgacctga gtatcaatag tcagatcctg cgttggttgc aggaagagat cgacgcccgg
    16921 cactttatct accgccgttt gcagacgggc gatgactttt tgcacccgat catcacgttc
    16981 atccaacggt ttgaggttga tttgtaaacg tgcactgttc agcgacgggt tagtgccatc
    17041 aacgccaaca aatgaggtca ggctttgcac tgccggatcc tgcaaaatca cgtccgcgac
    17101 ctggcgttgt cgctgggcca tattggcaaa ggagctggat tgcggtgcct gcaaagtgcc
    17161 ctgaataatg ccattgtcct gtaccgggaa gaaacctttc ggaatgaaca cccacagcag
    17221 cacgctaagc agcagcgtgc tgagtgccac gcttaaggtc agccacggat gattcagcac
    17281 tttcgccagt ccacgaccat aggcggcgat tatcctgtcg aacatttttt ccgaggcacg
    17341 ggagaagcgg ttctgtttac gcaacgactc ctggctgagc atccgcgcgc acatcatcgg
    17401 tgtcagggtc agcgacacca ccgctgagat caaaatcgct accgccaggg taatagcaaa
    17461 ttcgcggaac agtcgcccga cgatatcgcc cataaacagc agtgggatca acaccgcaat
    17521 cagtgagaag gtcagcgaga taatggtaaa gccgatttca cctgcgccct tgagcgccgc
    17581 cgccaacggt ttttcgcctt tttcgatata gcgggaaatg ttttcgatca ccacgatggc
    17641 gtcatcgacc acgaatccgg tggcgatagt taacgccatc agtgtcaggt tattgattga
    17701 aaaatcgaga aataccataa ccgcgaaagt gccgattaac gacagcggta cagcaacacc
    17761 gggaatgatg gtcgccggaa tattgcgcaa aaacaggtag ataatcatga ctaccagcgc
    17821 gatagccatc atcaattcaa actgagtatc atcgacggat gcgcggatat tggtggtgcg
    17881 atcggaaagc actgtcacct tcaccgattt cggcagactc tcagtgagct gtggcagcat
    17941 ctgccgaatg ctgtcggcgg tggagataat gttagcaccg ggctggcgct gaacattcat
    18001 cacaatggcc tgttctttgt tcgcccacgc gccgagccag ctgttttctg caccttgctc
    18061 tacagttgcg acatcgccca gacgaattgg cgcgccgttc tggtaggcga tgattagctg
    18121 gcgatactct tcggcggatt gcatctggtc gttcgcggaa agcgtgaccg cacgggaagg
    18181 gccgtcgagg ctaccttttg ccgagttaac gttagcgccg gtaatggcgg tgcgcacggt
    18241 ttcgctggtc aggccgaggg cggcaatcgc ctgagcgtta agtttgacgc gaacagccgg
    18301 acgctgaccg ccggaaagcg tcaccaggcc gacgccggaa atctgcgaga ttttctgcgc
    18361 gacgcgggtt tccaccatat cttccacttg cgtcatcggc atggcggttg aggtgacggc
    18421 gagcgtcatg atcggcggat ctgccgggtt cactttgctg taaaccggcg ggttaggcag
    18481 atcgctcggc aacaagttgg tcgcagcgtt aatcgcggcc tgcacttcct gctcggcgac
    18541 atcgagcggt aatgttagct ggaactgcaa agtgataact gacgcaccgc cggaactttg
    18601 cgacgacatc tgtttcaggc cagacatctg cccgaactgg cgttcgagcg gcgcggtaac
    18661 ggcagaggtc atgacatccg ggctggcacc tgggtagagc gtgaccacct gaatggtcgg
    18721 atagtccact tccggcagcg ccgaaacggg cagggcgcga taaccgataa tcccggcgag
    18781 taagatcgcc accatcagca gcgtggtggc gacaggacgc ataataaaca ggcgcgacgg
    18841 gccgcctgtg ctgctcgggg gtaacacctg catcaggagc gtgctccttt tttcgcgtat
    18901 tcgcggctgg tggctttctc ttccggagtg gtggcgctct gggcttccac cacttccact
    18961 ttcgcccctt cggtcaggcg atcaatgccg tctgtcacca cgcgatcgcc cgcagaaata
    19021 cctgcacgga tcaccacttt ctgactgtcc tgaatgcccg gcgtcaccag atgtttgctg
    19081 accttgtttt cgctattcag cacccagaca aaatggcctt cattgcccat ttgcagggcg
    19141 gctgttggga tcactacggc gttttgttcg gtgtcgacta acatgcgcgc gttaacaaac
    19201 tgattgggaa acagcgcatc atcctgatta ttaaagcgtg ctttcacttt aatcgtaccg
    19261 gttgtggcat cgatttggtt atcgaggctt aacagcgtgc cttcacttaa tttcttcgaa
    19321 ttggtgcgat cccaggcttc taccaccagc ggttttccgg ctttttgcgc ctgcactaca
    19381 gtagcgatat cgctttccgg cagggtaaag actaaatcga taggatgcgt ctgggtgatc
    19441 accacaattc cggtggtatc accactggag atttggttac caacatcaac ctgcttgaga
    19501 ccaacgcgac catcgactgg tgcggtgatg cggctccagt cgagttgcaa ctgcgcgctg
    19561 gcgacgcttg cttcatcagc cttaatggtg ccttcggttt cactgaccag cgcctgttgg
    19621 gcatccagct cctgacggga gacgagattg gtttttgcca gttgctgata acgcgccaga
    19681 tcacggcggg cgttagcaag cgtggcttta tcttttgcca gttggccctg ggtttgtgct
    19741 aatgcaactt tgaactggct ggggtcaatt tctgccagta aatcgcctgc tttgacctgc
    19801 tggccttcct ggaaatgtaa cgccatcagt tgaccgtcca cgcggctgcg caccgtaaca
    19861 gtattagcgg cgataatggt gccaagcccg gtgaggtaac gcggaactgc ctgttctacg
    19921 gcggtcgccg cctgaaccgg ggctaatggg ccggaacgca taccacggcg accacccgct
    19981 ggcgattgct gcgcttgttt cgtcgcccct ggggctgcac tctgggagtc attgcggcct
    20041 tgccagaacc agaatgcggc gatggcggcg ataaccacca cgattacgat tacccaacgg
    20101 gatttataac tacctttcat cgttaagagt ttctcttcct gaaacgtttc gcggaatgat
    20161 actagtgtag ccagccaata agggagaaaa atggaggaat tatgaaacac tgtctggaat
    20221 cgtctgaatg acgggcacat ttgcgagcac ccatccagta ataacacagg aaactatttt
    20281 atctacgcgt tagcgataga ctgcattcag ggcaaaagga ggtaggccga
//
LOCUS       DACAOP010000086        19847 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.086, whole genome shotgun sequence.
ACCESSION   DACAOP010000086 DACAOP010000000
VERSION     DACAOP010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19847
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.086"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(12..470)
                     /locus_tag="IT892_003363"
     CDS             complement(12..470)
                     /locus_tag="IT892_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAP3136546.1"
                     /translation="MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATI
                     RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG"
     gene            590..1399
                     /gene="proC"
                     /locus_tag="IT892_003364"
     CDS             590..1399
                     /gene="proC"
                     /locus_tag="IT892_003364"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAP3136547.1"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAA
                     LHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTL
                     DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
                     GEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
     gene            complement(1416..2531)
                     /gene="adrA"
                     /locus_tag="IT892_003365"
                     /gene_synonym="dgcC"
     CDS             complement(1416..2531)
                     /gene="adrA"
                     /locus_tag="IT892_003365"
                     /gene_synonym="dgcC"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase AdrA"
                     /protein_id="HAP3136548.1"
                     /translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
                     RAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNL
                     KTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
                     TGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
                     YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
                     ITLRGSDVIGRFGGDEFAVIMSGTPAESAITTMLRVHEGLNTLRLPNTPQVTLRISVG
                     VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
     gene            complement(2633..2953)
                     /gene="psiF"
                     /locus_tag="IT892_003366"
     CDS             complement(2633..2953)
                     /gene="psiF"
                     /locus_tag="IT892_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414918.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="HAP3136549.1"
                     /translation="MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQA
                     LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
                     KKAA"
     gene            complement(3072..4487)
                     /gene="phoA"
                     /locus_tag="IT892_003367"
     CDS             complement(3072..4487)
                     /gene="phoA"
                     /locus_tag="IT892_003367"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HAP3136550.1"
                     /translation="MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
                     RRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
                     TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
                     AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLL
                     NARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKP
                     LLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
                     NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADH
                     AHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
                     VVGLTDQTDLFYTMKAALGLK"
     gene            complement(4588..4848)
                     /gene="iraP"
                     /locus_tag="IT892_003368"
     CDS             complement(4588..4848)
                     /gene="iraP"
                     /locus_tag="IT892_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraP"
                     /protein_id="HAP3136551.1"
                     /translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
                     QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ"
     gene            complement(5030..5233)
                     /locus_tag="IT892_003369"
     CDS             complement(5030..5233)
                     /locus_tag="IT892_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136552.1"
                     /translation="MLQSSADKACNVLVKKVRYLKDVRKITKMMNGKLIYSWLKWPCG
                     EFFSLNYKLTKRIYFITFIYNKG"
     gene            5311..6405
                     /locus_tag="IT892_003370"
     CDS             5311..6405
                     /locus_tag="IT892_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase A"
                     /protein_id="HAP3136553.1"
                     /translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
                     KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
                     LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKV
                     IVEQGIKGREIECAVLGNDNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
                     EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLITRLIELALERHAADNALKTTM"
     gene            complement(6429..6641)
                     /locus_tag="IT892_003371"
     CDS             complement(6429..6641)
                     /locus_tag="IT892_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414914.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2754 domain-containing protein"
                     /protein_id="HAP3136554.1"
                     /translation="MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVG
                     LVTWVISFWLAGLIIRRRDEETENAQ"
     gene            6901..7209
                     /locus_tag="IT892_003372"
     CDS             6901..7209
                     /locus_tag="IT892_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2755 family protein"
                     /protein_id="HAP3136555.1"
                     /translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
                     LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
                     "
     gene            complement(7268..8362)
                     /gene="yaiW"
                     /locus_tag="IT892_003373"
     CDS             complement(7268..8362)
                     /gene="yaiW"
                     /locus_tag="IT892_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-exposed outer membrane lipoprotein YaiW"
                     /protein_id="HAP3136556.1"
                     /translation="MSRVNPLSSLSLLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQ
                     KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
                     WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLINMVPM
                     GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
                     NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTE
                     LATRKLAAKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAETKTGKSLPREMLPGI
                     QLESPKITRNLTTAWFAKRVDERRARCMKQ"
     gene            complement(8375..9595)
                     /gene="sbmA"
                     /locus_tag="IT892_003374"
     CDS             complement(8375..9595)
                     /gene="sbmA"
                     /locus_tag="IT892_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter SbmA"
                     /protein_id="HAP3136557.1"
                     /translation="MFKSFFPKPGTFFLSAFVWALIAVIFWQAGGGDWVARITGASGQ
                     IPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
                     HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSAHVPELPIIGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
                     AAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
                     LDGDKIQEVTHTLS"
     gene            9947..11104
                     /locus_tag="IT892_003375"
     CDS             9947..11104
                     /locus_tag="IT892_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OXA-12 family class D beta-lactamase AmpH"
                     /protein_id="HAP3136558.1"
                     /translation="MKRSLLFSAVLCAASLTSVHAAQPITEPEFASDIVDRYADHIFY
                     GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVVRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
                     DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
                     SNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
                     ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
     gene            complement(11105..11728)
                     /gene="iprA"
                     /locus_tag="IT892_003376"
     CDS             complement(11105..11728)
                     /gene="iprA"
                     /locus_tag="IT892_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide resistance inhibitor IprA"
                     /protein_id="HAP3136559.1"
                     /translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNNEDT
                     FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
                     ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
                     GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
     gene            complement(11816..14638)
                     /locus_tag="IT892_003377"
     CDS             complement(11816..14638)
                     /locus_tag="IT892_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HAP3136560.1"
                     /translation="MHSWKKKLVVSQLALACTLAITSQANAANYDTWTYIDNPVTALD
                     WDHMDKAGTVDGNYVNYSGFVYYNNTNGDFDQSFNGDTVNGTISTYYLNHDYADSTAN
                     QLDISNSVIHGSITSMLPGGYYDRFDADGNNLGGYDFYTDAVVDTHWRDGDVFTLNIA
                     NTTIDDDYEALYFTDSYKDGDVTKHTNETFDTSEGVAVNLDVESNINISNNSRVAGIA
                     LSQGNTYNETYTTESHTWDNNISVKDSTVTSGSNYILDSNTYGKTGHFGNSDEPSDYA
                     GPGDVAFTSTWNSNFDPNGHDSNGDGVKDTNGGWTDDSLNVDELNLTLDNGSKWVGQA
                     IYNVAETSAMYDVATNSLTPDATYENNDWKRVVDDKVFQSGVFNVALNNGSEWDTTGR
                     SIVDTLTVNNGSQVNVSESKLTSDTIDLTNGSSLNIGEDGYVDTDHLTINSYSTVALT
                     ESTGWGADYNLYANTITVTNGGVLDVNVDQFDTEAFRTDKLELTSGNIADHNGNVVSG
                     VFDIHSSDYVLNADLVNDRTWDTSKSNYGYGIVAMNSDGHLTINGNGDVDNGTELDNS
                     SVDNVVAATGNYKVRIDNATGAGAIADYKDKEIIYVNDVNSNATFSAANKADLGAYTY
                     QAEQRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGA
                     WVSYFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSG
                     QVDQDSQTAYIYSSAHFANNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFG
                     LKAGYDFKLGDAGYVTPYGSVSGLFQSGDDYQLSNDMKVDGQSYDSMRYELGVDAGYT
                     FTYSEDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSA
                     YTDANYLGGGDVDQDWSANVGVKYTW"
     gene            15162..16136
                     /gene="hemB"
                     /locus_tag="IT892_003378"
     CDS             15162..16136
                     /gene="hemB"
                     /locus_tag="IT892_003378"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HAP3136561.1"
                     /translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
                     KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEY
                     AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
     gene            complement(16243..17094)
                     /gene="tauD"
                     /locus_tag="IT892_003379"
     CDS             complement(16243..17094)
                     /gene="tauD"
                     /locus_tag="IT892_003379"
                     /EC_number="1.14.11.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine dioxygenase"
                     /protein_id="HAP3136562.1"
                     /translation="MSERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQV
                     VFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
                     TFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
                     EYKYRKTEEEHQRWREAVAKNPPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKES
                     EALLSFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
                     KPFYRAG"
     gene            complement(17091..17918)
                     /gene="tauC"
                     /locus_tag="IT892_003380"
     CDS             complement(17091..17918)
                     /gene="tauC"
                     /locus_tag="IT892_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter permease TauC"
                     /protein_id="HAP3136563.1"
                     /translation="MSVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVATL
                     QLISPLFLPPPQQVLEKLLTIAGPQGFMDATLWQHLAASLTRIMLALFAAVLFGIPVG
                     IAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
                     ALAGVKSVQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
                     LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
     gene            complement(17915..18682)
                     /gene="tauB"
                     /locus_tag="IT892_003381"
     CDS             complement(17915..18682)
                     /gene="tauB"
                     /locus_tag="IT892_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter ATP-binding subunit"
                     /protein_id="HAP3136564.1"
                     /translation="MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLL
                     NLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGIEK
                     MQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
                     AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSSGPGRVLERLPLNFA
                     RRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS"
     gene            complement(18695..19657)
                     /gene="tauA"
                     /locus_tag="IT892_003382"
     CDS             complement(18695..19657)
                     /gene="tauA"
                     /locus_tag="IT892_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3136565.1"
                     /translation="MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
                     FAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVSIEVFLLASKL
                     GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
                     IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHP
                     EVVKAFAKSAIDAQQPYIANPDVWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQ
                     QQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ"
BASE COUNT         4931 a         5185 c         4774 g         4957 t
ORIGIN      
        1 ataaattaca tttagccacg actacgttgc acttccagcc accacttctc cagctccgcg
       61 gcaaaggcct ggcggtcacg ttgtgaaagg ctatctggtc cgccggtctg gatcccactg
      121 gcacgtaagg tatccataaa atcgcgcatc gtcaggcgct cacgaatggt cgctggcgtg
      181 taacgttcgc cgcgcggatt aagcgccgca gcgcctttct cgatggcttc agcagccaaa
      241 ggtatatctg cggtgatcac caaatcgccc gcttcacact gccggacaat ttcgttatcg
      301 gcaacgtcga aacctgccgc gacgcgcagc gtacgaataa atcgcgatgg cggcacgcgt
      361 aaactctggt ttgctaccag taccagcggc atctgcatac gttccgccgc gcgatacaaa
      421 atctctttaa ttacattggg acacgcgtcg gcatccaccc aaattgtcat aaagtcatcc
      481 tttgttgggt aatcctctat tgtgtcgcgc ttttgccttc cggcatagtt ctgtttatgc
      541 ttctgccagc gattatcaaa acaatgaatt tcacggcagg agtgaggcaa tggaaaagaa
      601 aatcggtttt attggctgcg gcaatatggg aaaagccatt ctcggcggtc tgattgccag
      661 cggtcaggtg cttccagggc aaatctgggt atacaccccc tccccggata aagtcgccgc
      721 cctgcatgac cagttcggca tcaacgccgc agaatcggcg caagaagtgg cgcaaatcgc
      781 cgacatcatt tttgctgccg ttaaacctgg catcatgatt aaagtgctta gcgaaatcac
      841 ctccagcctg aataaagact ctctggtcgt ttctattgct gcaggtgtca cgctcgacca
      901 gcttgcccgc gcgctgggcc atgaccggaa aattatccgc gccatgccga acactcccgc
      961 actggttaat gccgggatga cctccgtaac gccaaacgcg ctggtaaccc cagaagatac
     1021 cgctgatgtg ctgaatattt tccgctgctt tggcgaagcg gaagtaattg ctgagccgat
     1081 gatccacccg gtggtcggtg tgagcggttc ttcgccagcc tacgtattta tgtttatcga
     1141 agcgatggcc gacgccgccg tgctgggcgg gatgccacgc gcccaggcgt ataaatttgc
     1201 cgctcaggcg gtaatgggtt ccgcaaaaat ggtgctggaa acgggagaac atccgggggc
     1261 actgaaagat atggtctgct caccgggagg caccaccatt gaagcggtac gcgtactgga
     1321 agagaaaggc ttccgtgctg cagtgatcga agcgatgacg aagtgtatgg aaaaatcaga
     1381 aaaactcagc aaatcctgat gactttcgcc ggacgtcagg ccgccacttc ggtgcggtta
     1441 cgtccggctt tctttgcttt gtaaagcgcc aaatctgccg atttcaacca ctcacgatag
     1501 tgactcattt gtgggttcag cggcgcaacc cccacactaa tccgtaaagt tacctgtggc
     1561 gtattcggca aacgtaatgt atttagccct tcatgcaccc gtaacatggt ggtaatggcg
     1621 ctctcagctg gcgtaccgga catgattact gcaaactcat cgccgccaaa ccgaccaatc
     1681 acatcgctac cgcgcagggt aatttgtaac tgtcgggtaa gcgccacaat cgcttcatcg
     1741 cccacatcat ggccccaggt atcgttgatg ctcttgaaat ggtcgatatc gataatcagt
     1801 aacgttgcat cgcgattatg ccgccgacag ttatcaaatt cattgcgtaa catagtttcc
     1861 caatgacgtc ggttatacac gcccgtcatg ccgtcgcggg tactcatgac ctgcaacctg
     1921 cgtttatgtt ccgccagttt ggttgccgtc tggtagctga cccagccaaa cagcagagga
     1981 taaatgacaa taatgggaag ggagagccac cattccagcg gcgcactatt gaacgacacg
     2041 gtaatgcccg tcagctcgag ggtgacaagg caggaaacca ccatcaacac cagacccgcg
     2101 acaaacagac gggggccgcc tgcccccatc aaattcagac acataatcat caacatcgcg
     2161 gtggaaggca gcacgtttac gcccattacg cctacccaca ttcccgctaa tactgcatcg
     2221 gtttttaagt tgtaaatttc ccggctaagc ggatcgacgg ccctgctcgc tatctgccag
     2281 gctaaatgcg gccagacgaa cgcccagccg accaacacca gccaccacca gcccggcggc
     2341 gggtgtgaaa ccagcgttga agcaatcggt aagaacatgc cagccaggcc aaccgcacgg
     2401 ggtagtctga cgcgacgggc gaagcgcagc ccggaccgct gatgttcgtt ttgaggagtt
     2461 aaaggaggtt cctccccgtg cgccgccgct tttttgaaaa agttttcatc attcattatt
     2521 tttgggaaca ttcagaaaca attttcccaa attatagaga cggagctaaa ggcagaagta
     2581 tgatatttcg ggtgagccat tttcgtagct cacccgttag cactatcagg tatcaggcgg
     2641 ctttcttgag gcaggcactc ataaacttat tacgatcatc acctttcaga gattgttgtg
     2701 ttgcttgatt attgcattcg cgcatctttt gctgctgtgg cgtcaaactt ttttcgccag
     2761 gcgcagactt gctgttcttc aggcaatcac tcatgtaggt cttacgagca tcccctttca
     2821 acgcctgcgc cgtcgcctgc tgattacagg aggtcatacg ctgttgttgt ggggttaaag
     2881 ttctctcggc agcgccgacg gtggttaaaa aaaccagacc gaaaagcaag gtaaccagta
     2941 atgttatttt catagcacca tccctcttca tgttttaacc atgagcgtat gcgcccgtga
     3001 tctgccatta agtctggttg ctaacagcaa aaaaaccacc cggcagcgaa aattcactgc
     3061 cgggcgcggt tttatttcag ccccagagcg gctttcatgg tgtagaagag atcggtctgg
     3121 tcggtcagtc caacaacatt ggcggcatgc gggccatacg ccgcaatacg caactgactg
     3181 ccggtatgtt cttgtgaatc ctcttcggag ttcccgtaac tcatcaccat cactgcgcca
     3241 tctttggtat ttagcgcctg ggtgaggccc ggagctttgg tatccggcgc aacaatctgg
     3301 ctggcgtggg cgtgatcagc ggtgactatg accagcgtgt taccctcctt tttagcgaat
     3361 tccagcgccc gttgtacggc ttcatcgaga tcgaccgtct cgccaatttg cccacaagga
     3421 ttcgcagcat gatcctgttt atcgattgac gcaccttcaa cttgcaggaa aaagcctttc
     3481 tcatttttac tcaacaattc aatggctttg tcggtcatct gcgccagggt tggtacactg
     3541 tcattacgtt gcggatttgg cgtacaggtg actgcgggct tatcgatatt gccatggtac
     3601 gttgctttcg gtcctagcca gcgcactggc atattgccgt cagcaaacag gccaagcagg
     3661 ggtttttgct gattcgcttc cgtcaccgaa ttcagtgagg cagcatcgct caccaactga
     3721 taaccacgcg cctgtgcctg ttcacgcagc gtttttccct gccattcacc agcggttgcc
     3781 gtttcagcaa aggtttttgc gccgccgcca agcgtaacgt cggcacgagc gttaagcagc
     3841 tgttcggtaa tcgatccttt tccgcctttt tccagagcgt tacccggaca tttttcactg
     3901 gtcgcgctcg gaccgtagca tttgcgcgag gtcacatgtg ccaccagcgc agcgggcgtg
     3961 gcatcctgca actctgcggt agaaacgtta ccggtcgcca gacctgcggc ttttgccatt
     4021 tccagaatcg ttgggtgatc tttttcgtga atatcgacgc ccagcgcgcc gttataggtt
     4081 ttgacaccgg ttgaccaggc ggttgctgat gcagccgagt cggtgacgta gtccggtttg
     4141 ccggtttttt tattcagcgc atagtgagtg tattgcccgg taagcggtaa ggcatctata
     4201 cctttaaaaa agccgcccgc accttcggca taattacgtg cggcagtaat ttccgagtcc
     4261 cccatcccat cgccaatcag caaaataata ttttttgcag gtttatcgct aagagaatca
     4321 cgcagagcgg cagtctgatc acccgttaaa cggcgagcac cgccgggtgc agtaatatcg
     4381 ccctgagcag cccggttttc cagaacaggc atttctggtg tccgggcttt tgtcacaggg
     4441 gtaaacagta acggtaagag tgccagtgca atagtgcttt gtttcacttt attttctcca
     4501 tgtacaaata cattaaaaaa taaaaacaaa gcgactataa gtctcggccg tgacaacttt
     4561 atgacagctg ttgaaaagat taacttttta ctgacgagga tgcttcaata acttctttac
     4621 gtaatcgcgc agcagctccg tatcgtcgtc aggaatgctg gcatcgggct ttacctcgta
     4681 cagcgccccc tctacctgat caatcaaccg ctgttggtca ttttgcgcca tattgcgaag
     4741 cattgcagtg acgataatct ccaaagcttc tacctgcgca cacagttctt tcgactcttc
     4801 ttctttttgg gcaagcttaa ataacaactc agcaatgaga tttttcatgt ctgtatttcc
     4861 ttatccaaag tatggagaag ttaacattat gtttcacaac ttcatagtgt ctggaagtat
     4921 tatttttatg acaaaggaaa tactttgcgc aaatattttt tgtttgatta ccagcgaaac
     4981 gtttctctta tttaaataat tacccacaca aaatataggc ttttaattat caacctttat
     5041 tataaataaa agttatgaaa tatattctct tcgttaactt ataattaaga gaaaaaaact
     5101 caccgcatgg ccatttaagc caggaataaa ttagcttccc gttcatcatt tttgtgatct
     5161 tgcgcacatc tttgagataa cgcactttct tcaccagtac gttgcacgct ttgtcagcag
     5221 aagattgcaa caatctttca gaaggccgcg aatcccccgt tttgtcgtgg taatgtatgc
     5281 actttgtgtt agacgggata ggtttttaag atggaaaaac tgcgggtagg aatcgttttt
     5341 ggtggtaaat cagcggaaca tgaagtgtct ctgcaatcgg caaaaaacat tgtcgatgcc
     5401 attgataaaa gtcgcttcga cgttgtgctg ctgggcattg ataaacaagg gcaatggcac
     5461 gtcagcgatg ccagcaatta tctgctaaat gcagacgatc ctgcccatat tgcgttgcgc
     5521 ccttcggcga ccagccttgc gcaggtgcca ggtaaacatg agcatcagct tatcgacgcg
     5581 caaaacggtc agccgttgcc gacggtggat gtcattttcc cgattgtcca cggtacgctg
     5641 ggcgaagatg gttccttgca gggaatgctg cgggtcgcca atttaccgtt tgtaggttct
     5701 gatgttctgg cttcagcagc ctgtatggac aaagatgtca ccaaacgtct gctacgcgat
     5761 gccgggctga acattgcgcc atttattacc ctgacgcgcg ccaatcgtca caacattagt
     5821 tttgccgaag tggagtctaa actggggtta ccactgtttg taaaaccggc taatcagggc
     5881 tcttctgttg gtgtcagcaa agtaaccagt gaagaacagt acgcaattgc cgtcgatctg
     5941 gcgttcgagt tcgatcataa agtgatcgtt gagcaaggga tcaaaggtcg tgagatcgaa
     6001 tgcgcagttc tgggcaacga caatccgcaa gccagcacct gtggagagat cgtactcacc
     6061 agcgatttct atgcctacga caccaagtac attgacgaag atggcgcgaa agtggtagtt
     6121 ccggcagcca ttgcgccaga aatcaacgat aagatccggg cgattgccgt tcaggcttat
     6181 caaacgttgg gatgcgcagg catggcgcgt gtagacgtgt ttttaacccc agagaacgaa
     6241 gtggtgatca acgagatcaa caccctgcct ggcttcacta atatcagtat gtatccgaag
     6301 ctgtggcaag ccagcggtct gggttacacc gatctgatca cacgtttgat tgaactggcg
     6361 ctggagcgtc acgctgcgga taacgcattg aaaaccacaa tgtaatattt taacgcccga
     6421 taatattctt attgggcgtt ttcagtttct tcatcgcgac gacgaataat caaccccgcc
     6481 agccagaaac taatcaccca cgtcaccaga ccgacggcat aggtctgcca accttttgct
     6541 tcaaatccca gtaaccccac cacgccatta agaatgaata taaggccaat ggcgaacgca
     6601 tagtagtgcc agtcacggcg gatttttaca ggcagattca tggcagctcc gttaacgaaa
     6661 aacaacatcc ttgcatattc tgcaacaacc gtctgtggtg tagacaacat tttcgtaatt
     6721 gttaataaat ttaacttaag gttgccattt tgtgactcac aacgaagatt cacgcttcgg
     6781 gaatattccc aacatcaatt taccatgatt ctgatattga caatctaaat gacctgtcag
     6841 acttgccata agccgctggt atcacaccag aagagaagca gatgacttcc ggaggttttt
     6901 atggctgatt tcaccctgtc aaaatcgctg tttagcggaa aatatcgcaa tgcctcttca
     6961 acgcctggca acattgccta tgcgttgttt gtgctgtttt gcttttgggc tggggcgcaa
     7021 ttgctgaacc tgttagtgca tgcgcccggc gtctatgagc gtttaatgca ggtccaggaa
     7081 acaggtcgcc cacgggtgga aattggttta ggtgtcggca ccattttcgg gctgatcccg
     7141 tttttagtag gctgcctcat ttttgcagtg gtggcgctat ggctgcactg gcgacatcgc
     7201 cgccagtaag ttttacattg tcagatgcgg cctgaaacgc cttatctggc ctgacattcc
     7261 tgtttgatca ctgtttcata caacgcgccc gccgttcgtc tacgcgcttc gcaaaccagg
     7321 ccgtagtcag gttgcgggtg attttcgggc tttccagttg aatgccaggc aacatttcgc
     7381 gggggagtga tttacccgtt ttcgtttcgg caagttgata aactttcttg tacagcgccg
     7441 tctcctcaaa agagaagctg tcacctttct ctaactgacg gcgaatttcg ctgtcgctca
     7501 tccccagttt tgcagccagt ttgcgcgttg ccagttcggt tttcccgggt tctttactgt
     7561 cgtaacgaat taaatcaccg tccagtgcca gcttcacgcc gctggcctta ctgaccgcgt
     7621 tctgaaacgc ggcattacgg ctggcgtacc agccagcgtt aaaatcagca aaacggtata
     7681 tcggtgcgct ataactggcg ggataattca gtaaatggta agtaccaaac cacaacccgc
     7741 cgcggcgact gaagacttcc tgacggactg taccgtccat tttccacgga taccctttgg
     7801 tatgctgttc ggcaaaagca atgctgacct gcatcggccc accggtgcgc accggattga
     7861 gcgaaccaaa cagcgtctgc cccattggca ccatgttgat cagatcgtca aaaatcgcgc
     7921 tcaattgctt ttctgtacgc accgaatcta accgttcgct ataacttttg ccgtttggcg
     7981 atttgatttt tagcgcggta tgaaccagaa aagcaggaat gtgcatccgt tcagcacgac
     8041 ggtcaatctc ttgccaggcg atcttgctta agcccggaac ggccggatct gcctgataat
     8101 ttgactcctg ctgcgccacc gccagcaccg agcagacgtt ttccagcgtc ggtgccagcc
     8161 cctgactttc aaaggtggtg gcgagatctt tcgcccaggc atcgcggtct ttcacgctcg
     8221 caggcatctt ctgccgcacg acgctcgcta catctatcgc tttttcgccc tttttcaacg
     8281 gttgcggagc ctgactacta caccccgcta aaaccagaac cgccaacaat gacagcgaag
     8341 atagaggatt gacgcgcgac attacttctc ctttttagct caaggtatgg gttacttcct
     8401 gaattttgtc accatccagc tcatgttcaa agctgcgcag acgtttgtag atagacatca
     8461 actcaaccag tgtggtccat gagttaatca ggtactggaa agcaccgcga acctgaccaa
     8521 aaacgttggt aatctgcgtc atcaggccga gcgtaatcgt accggcaaca attgacggaa
     8581 acagcaagaa caaaccgaaa acgttatcga cctgcaaata gagaatgcgg gcgatgttga
     8641 aatacatata gtgaaaatag aggcggaaat agtttttccg tacggcgcta aacagctcgc
     8701 gtaccgtagg cggcgtcgcg cgcgtggcat cgtcttcacc ataaaccagc tctttacggt
     8761 aggcagcctc tacacgctgg tttttaaact ccagccccgg cagtttgatc cctaccactg
     8821 ccagcaatcc ggtccccatc agcgaccaga cgattgcggc aatcaccaga ccatacggaa
     8881 tgtgcccgat aatcggcagc tccggcacat gcgcggagag cgttaccagc accggcagga
     8941 aggcgatcaa cgtcatgatg gcgttgataa aactgacgcc catattctcc agcgttgaag
     9001 caaaacgcat ggtgtcttcc tgcacacgct gtgcggcccc ttcgatatga cgcagttgtt
     9061 gccagttcgc catgtaatat tcgttcatcg ctgtacgcca gcggaacacg tagtgactga
     9121 caaagaagtt gttcagcaca ctgatcacca cagcgatcag cgcaatcccc agaaagacgc
     9181 ccacttcgcg gtaaaattgt tcgatggtga ctttatgcgg cgaacttagc gcggtttgaa
     9241 tcagatcata gaacggcgca taccaggcgt tgacggcgac cccgacttcc accaaaaacc
     9301 aggtgacgaa gatgatcagt gcagtaccga gtattgacca gtattgccaa cgatgcgggc
     9361 tgtagataaa ccagaacaat gcaaaaagtc ctacgcaaac aatgtagtaa gcgtaaaaaa
     9421 tcaggaaatc caacgaccag aaacgcgcgg cgctaatcgg gatctgcccg gaagcgccgg
     9481 tgatacgcgc cacccagtca cccccaccgg cttgccagaa gataacggca atcaatgccc
     9541 aaacgaaggc cgagagaaaa aacgttcccg gctttgggaa aaaagactta aacatatgca
     9601 ctcctgctaa cttcttatcg ttttaacaac tgctgtgtat taaccgcatg accgctacaa
     9661 agcgtcagcc aaatgaaacc gcccattgtg acccatagca aggcgcttag ttcgccagcc
     9721 tgaccataag aattgtttcg acggatttca caaaccaaag attgtttaca taagcggatt
     9781 aacacgcgca ggatcacaaa tgcaggcatt ggtgagcagg aaaaagatcg tgtttacgcg
     9841 ccgttacgtt tttaacacta ttattgcact aattcgccct ttgcaatcta tcaatgagta
     9901 gtataaatac gctcagttac cttcattcaa tctatggaca ccaccgttga aacgtagtct
     9961 gcttttttct gccgtgctgt gtgcggcgtc attgacctcc gtccatgcgg cgcagccgat
    10021 cactgaaccg gagtttgcct ctgatattgt cgatcgttat gccgatcata ttttttacgg
    10081 cagcggtgcc acggggatgg ctctggttgt tatcgacggt aaccagcgcg tctttcgcag
    10141 ttatggcgaa acgcgacctg gtaataacgt tcgcccgcag ctggattcgg tcgtgcgtat
    10201 tgcttccctc accaagctaa tgaccagtga gatgctggtg aaattgctcg accaggggac
    10261 cgtgaagtta aacgatccgc taagtaaata tgctccgcca ggcgcacgcg tgccaaccta
    10321 caatgggacg cccattacgc tggtcaatct ggcaacccat accagcgccc tgccccgtga
    10381 acagcccggt ggcgcggcac atcgtccggt gtttgtctgg ccaacgcgcg agcaacgctg
    10441 gaaatacctt tctacggcga agctgaaagc cgcgccaggc agtcaggcgg cgtactctaa
    10501 ccttgcgttc gacctgctgg cagatgcact ggcgaatgcg tccggcaagc cttataccca
    10561 gttgtttgaa gagcagatta cccgtccatt ggggatgaaa gacaccacct acaccccctc
    10621 accggatcag tgccgccgtt taatggttgc tgagcgcggt gccagtccgt gcaataacac
    10681 gctggcggca attggcagcg gcggcgtcta ttccacgcct ggcgatatga tgcgctggat
    10741 gcagcagtat ttgtcatctg atttttatca gcgcagtaac caggcagatc gcatgcagac
    10801 gttgatttat cagcgcgcgc agtttacgaa agtgattggc atggatgtcc ccggcaaagc
    10861 ggatgcgctt ggtttaggtt gggtatatat ggccccgaaa gagggtcgtc cggggattat
    10921 tcagaagaca ggcggtggtg gcggtttcat tacctatatg gcgatgatcc cgcagaagaa
    10981 tattggcgcg tttgtggtgg tcactcgttc gccgttgacg cgctttaaaa atatgagcga
    11041 tggcatcaat gacctggtga ccgagctaag cgggaataaa ccgttggtta tccccgcgtc
    11101 ctgattaata ctctgaaggc aaacggttga tagcgaccag tttgccttta ttcatttcga
    11161 tatagccgcc tttacgcaaa gcagcgagaa cttctgcgac gacagaacgc gatatgcgtg
    11221 tacgttgatg gatataattc atcacaccaa tacgtgatcg caattcttca ttccagtcaa
    11281 tcattgataa taatgttgcg cggatttgtt cgtaggaatt atgcccaatg agctgcacgt
    11341 cgcgtaattc cagaattcta ttttgccagg ctaaccagta aaaagcgtct cgccagagtt
    11401 gattttgttc aataagcgta atggtttgtt tggctggtag atgatatccc gtacaatttc
    11461 cttctgatat taatttgtat ggtatatcgt ttttcattaa accatcagcc agccccataa
    11521 tataaggagc ctgggtaata ccgataagta cgttttcttc tctacgcaga gagataactc
    11581 cctctaaaat aacgaaagta tcttcgttat tgacatcact ggaaaatata acttgctttt
    11641 cattattaaa ctcgaagcgc gtaccgtatc tggacaaaca tttatcgagc ttaccaaatt
    11701 cctgaagagg tttaactaca gataacattt gcgcgtcctt tgcagtaatg cccgtcaaat
    11761 ccttgacggg cattatttag attaaattac cagtatttct tcggagtgaa gaatattacc
    11821 aggtatattt aacacccacg ttcgcggacc agtcttgatc tacgtcacca ccaccgaggt
    11881 agttagcatc ggtataggcg ctgaagttct tggtgaagct gaactgagta cccagaccaa
    11941 cacgtaccgc agacccttca gtaccgttat cgatggaatc gccgttcaca tcgttatcgt
    12001 tgttagagtc gtcgtagacg taagccagtt tgaagtacgg agtcagagcc tgatcttcgc
    12061 tgtaggtgaa ggtataacct gcatctacac ccagttcata acgcatgctg tcgtaagact
    12121 gaccgtcaac tttcatgtcg ttgctcagct ggtagtcatc accagactgg aacagaccag
    12181 aaacgctgcc gtaaggagtc acgtaaccag catcacccag tttgaagtcg taaccggctt
    12241 tcaaaccgaa gccccaagcg tcggagttgg tgctaccgtc aacgtaagta ccgttgctca
    12301 tggttgcaga caggtcgttg ttgaagtgag agtagctcaa gctaccatca acaaagacgt
    12361 tgttcgcgaa gtgagcagaa gagtagatgt aggcagtctg gctgtcttga tccacctgac
    12421 cagaacggtc attcatgtca cctttagcga agcctgcagc cgcaccgacg atccacttag
    12481 cgttgttacc gtcaattttg gtatcaacac cgaccatgat gccgttaaca tcctgatcat
    12541 agttgatggt gccgttgtcg ccgttgaagt taccaccgaa gtagcttacc catgcgccgc
    12601 cgttatcagc caggccatga cgagagttgg tcagacgagt accaacggtg tcttgttcca
    12661 ggttccagat attggtgttc gcagacggga tgctcagcgc catgttagcg tagtcggtca
    12721 gctccatctg ttgcagaaca acggtgttac cgcgctgttc agcctgatag gtgtatgcac
    12781 ccaggtcagc tttgttagca gcagagaagg tcgcgttgct gttgacgtcg tttacgtaga
    12841 taatttcttt atctttgtaa tcagcgatag cgccagcgcc agttgcgttg tcgatacgaa
    12901 ctttgtagtt accggttgca gcaacaacat tgtctacaga gctgttatcc agttcagtac
    12961 cgttgtctac gtcgccgtta ccgttgatag tcaggtgacc atcagagttc atagcaacaa
    13021 taccgtaacc gtagttagac ttggaagtat cccaggtacg gtcgttcacc agatcagcgt
    13081 tcagaacgta atcgctgcta tggatatcga acacaccaga tactacgtta ccgttatggt
    13141 cagcgatgtt gccgctggtc agttccagtt tgtcagtacg gaaagcttca gtatcgaact
    13201 gatcaacgtt cacatccaat acaccgccgt tagttacggt gatagtattg gcgtacaggt
    13261 tgtaatcagc cccccaccca gtagattcgg tcaacgcaac agtactgtag gagttaatag
    13321 tcagatgatc ggtatcaacg tagccatctt caccaatgtt cagcgaagaa ccgttagtta
    13381 aatcgatagt atctgaagtt aatttagatt ccgaaacatt aacctgagaa ccattattaa
    13441 ctgtcaaggt atcaacgatg gaacgacctg tagtatccca ttcagaaccg ttattcaacg
    13501 ctacgttaaa tacaccgctc tggaagacct tgtcatcaac aacacgtttc cagtcattgt
    13561 tttcatatgt tgcatcagga gtaaggctgt ttgtagcaac atcatacatt gctgacgttt
    13621 cagcaacgtt ataaattgcc tgaccaaccc acttgcttcc gttatcgaga gtgagattta
    13681 gttcatcaac gttgaggcta tcatcagtcc aacccccgtt ggtatctttc accccgtcac
    13741 cgttggaatc atgaccattc ggatcaaaat tactattcca ggtgctggta aaggcaacat
    13801 cacccgggcc agcataatca ctcggttcat cagaattgcc aaagtgacca gttttgccat
    13861 aagtattgct atccaggata taatttgaac ccgaagtcac tgtggaatct tttacagaga
    13921 tattgttatc ccaagtatga gattcggtag tgtaggtttc gttgtaagta ttaccttgag
    13981 ataatgcaat acctgcaacg cgggagttat tggaaatatt gatgttactt tctacatcaa
    14041 gattaacagc aacgccttca cttgtatcaa atgtctcatt tgtgtgcttg gttacatcac
    14101 catctttata agaatcagtg aagtaaagag cttcataatc atcatcaata gtagtgttag
    14161 caatgttcaa agtgaaaaca tcaccatcac gccagtgtgt atcaacaacc gcatcagtgt
    14221 aaaaatcata tccacccaga ttattaccat ctgcatcaaa acgatcataa taaccgccag
    14281 gcagcataga agtaatcgaa ccgtgaatca ctgaattact gatatcaagc tgattagcag
    14341 tactgtctgc ataatcatgg ttcaaataat aggttgagat cgtgccgtta acggtatcgc
    14401 cgttaaagga ctgatcgaaa tcaccattgg tgttgttgta atagacaaaa ccactatagt
    14461 ttacatagtt gccatctaca gtgcctgcct tatccatatg atcccaatca agtgctgtaa
    14521 cgggattatc gatataagtc caggtatcat agtttgctgc attagcctga gaggtgatag
    14581 ccagagtgca agccaatgct aattgtgata ctacaagttt ctttttccag gagtgcattt
    14641 gtcatccctc ctcagggacg taataagttg atccatcaat tatcaatgca tagaaaacat
    14701 attatgtttc gcgctaacga ttatgctgcg ttacagacga atggttcaat tattctttcc
    14761 cctaagtccg aatgtggaca tatataattt atggagaaaa acacgcatca aattcataaa
    14821 agcacagtat ttcaacatgt tgcagataat tttgtttttg aagcatacgc ataataaata
    14881 tcacaaacac aaaccagata aatatcctat gaatatgcaa caaagtttta attattcaat
    14941 ttatagcagc gcaaccaaac tccaaaaaat aataaccaac agctataaat aaagattaaa
    15001 aatattttca gtgaatataa aattattgct gtttctatta aaaagatgtc ctggcctctc
    15061 ttccattctc ttcttgtcaa catcgcgaca actttcgtaa aacatcccta ccctgcttca
    15121 ggtatactat gcccctcgat tccacaaaca tcaggcagac catgacagac ttaatccaac
    15181 gccctcgtcg cctgcgcaaa tctcctgcgc tgcgcgctat gtttgaagag acaacactta
    15241 gccttaacga cctggtgttg ccgatctttg ttgaagaaga aattgacgac tacaaagccg
    15301 ttgaagccat gccaggcgtg atgcgcattc cagagaaaca tctggcacgc gaaattgaac
    15361 gcatcgccaa cgccggtatt cgttccgtga tgacttttgg catctctcac cataccgatg
    15421 aaaccggcag cgatgcctgg cgggaagatg gactggtggc gcgtatgtcg cgcatctgca
    15481 agcagaccgt gccagaaatg atcgttatgt cagacacctg cttctgtgaa tacacttctc
    15541 acggtcactg cggtgtgctg tgcgagcatg gcgtcgacaa cgacgcgact ctggaaaatt
    15601 taggcaagca agccgtggtt gcagctgctg caggtgcaga cttcatcgcc ccttccgccg
    15661 cgatggacgg ccaggtacag gcgattcgtc aggcgctgga cgctgcggga tttaaagata
    15721 cggcgattat gtcgtattcg accaagttcg cctcctcctt ttatggcccg ttccgtgaag
    15781 ctgccggaag cgcattaaaa ggcgaccgca aaagctatca gatgaaccca atgaaccgtc
    15841 gtgaggcgat tcgtgaatca ctgctggatg aagcccaggg cgcagactgc ctgatggtta
    15901 aacctgctgg agcgtacctc gacatcgtgc gtgagctgcg tgaacgtact gaattgccga
    15961 ttggcgcgta tcaggtgagc ggtgagtatg cgatgattaa gttcgccgcg ctggcgggtg
    16021 ctatagatga agagaaagtc gtgctcgaaa gcttaggttc gattaagcgt gcgggtgcgg
    16081 atctgatttt cagctacttt gcgctggatt tggctgagaa gaagattctg cgttaatttt
    16141 gtttcctctc agaaaggggg agttaacctg ttgaaagtac ggtgaacgcc ccctcaccct
    16201 aaccctctcc ccaagggggc gaggggaccg tccactctcg tattaccccg cccgataaaa
    16261 cggtttatcc ccaaggatcg tcgcccgatg cattatccgt cgctgtggca ggtaatcggc
    16321 attggcatag tgctgggtca cgcggttatc ccaaatcgca atatcatttg gttgccagcg
    16381 ccagcgcacc tgaaactccg gtttggtgat atgggcaaac aaaaaactta acaaggcttc
    16441 gctctctttc tcgctcacat caacaattcg cgtagtaaag ccttcattca caaacagcgc
    16501 ctgtttaccg ctcaccggat gcgttcgcac caccggatgt agcaacggcg ggtttttcgc
    16561 gaccgcctcg cgccagcgtt gatgttcctc ctcggttttg cggtatttgt attccgggaa
    16621 cgatttacgg aaatcatgct ccgcacgcag cccactcagc agctggcgga agggaacaga
    16681 gagcgcctca taggccgcaa taccgctggt ccagagcgta tcaccgccgg tcgaaggtaa
    16741 ctctttagct gccagaatcg cccctgcggg tggcgtttca ataaatgtca catcggtatg
    16801 ccagttgtcg ttatctggcg gattatcgtt atgggtatcc agcacgatga tctcgtcaac
    16861 cccttcggca tgcgggtaaa cagggtgaat atgcaattcg ccaaaacgct gggccagcgc
    16921 gcgttgctgc tgcggcgtaa tagcttgatc gcgtagaaac accacctgat ggcgcagcac
    16981 cgcatggtaa agctgttcaa actgattatc gcttaacggg cgcgtcaggt cggcacccga
    17041 aatttgtgcg ccgatatacg gccccagcgg ggtaatgctc agacgttcac tcattgtact
    17101 tctccatgcc agggcgtcag gcggcgctgt aacgcgcgca gacccagttc taaaagaaag
    17161 gcgataatcg caatcaccgc gatccccgcc agcaccacgt cagttgcgag aaattcaccc
    17221 gctgactgaa ccataaatcc taaaccgcgc gtcgcggcaa tcagctccgc cgccaccagc
    17281 gtagaccagc ccacccccag accaatacgt aatccggtga ggatttccgg cagcgcaccg
    17341 ggcaaaatga caaaccacag cacctgcgca cggctggcac ccagcgactg ggcggcacga
    17401 atgcgaacct gctgcacgct tttcaccccc gccagcgccg acatcgccac cggtgcaaaa
    17461 atcgctaaat agatcagtaa gatcttcgag gtttcaccaa taccaaacca gatcaccatc
    17521 agcggcaaat aagccagcgg cggcaccgga cgataaagct cgattatcgg atccagaatg
    17581 ccgcgtaccg tagggctaag tcccatcgcg atcccgaccg gaataccgaa caacaccgct
    17641 gcaaatagcg ccagcataat gcgcgtcaga ctggctgcca gatgctgcca cagcgtggcg
    17701 tccataaagc cttgcggtcc ggcaatggtg agtagttttt ccagtacctg ttgcggcggc
    17761 ggcaaaaata gcgggctaat cagttgcagc gtcgccaccg tccaccatac ggtgagtaaa
    17821 accgctaacg tgccaatgct taaggtcacc tgacgcgaga gcggccagcg ccatttcagc
    17881 cgccgcgaat gcagtttttc attaatgagc acactcatga gaacgcctcc cgttgctcaa
    17941 atacgcggct taaaacatat tcgcgcatgg cgatgaattg tggatcggac ttgatgctgc
    18001 ggctcgactc tcccgcaaca aagcggcgag caaagttgag cggcagccgc tccagcacac
    18061 ggccagggcc ggatgaaagc agaaccagtt cagtcgccat aaacaccgct tcttctatat
    18121 cgtgggtaat caacagcacc tgcttgcccg tctcctgcca gagtttcagc agcagggttt
    18181 gcatctggtc gcgggtgaag gcgtccagcg caccaaacgg ttcgtcgagt aataacagct
    18241 ggggattcgc cgccagcgca cgagcaatcc ccacccgctg acgttgacca ccggaaagct
    18301 gccagatgta gcgtttttct gcgccttcca gccccacttt tttcagcatc tggtgcgcga
    18361 tttccagtcg ctgcattttc tctatacctg ccaattgcag gccgaacgcc acgttgtcct
    18421 gtacattgcg ccacggtagt agcccttcat tctgaaaaac tacgccacgc tctgctcccg
    18481 gtccctcaat acgcttaccc gccagttgaa tgctgccatg ctgataaggc acaaaaccgg
    18541 caatcagatt cagcagggtg gttttaccgc agccggacgg ccccagcacc accagtagct
    18601 cgccgctttc cagcgtcagg ttgatatctt ccagtgccgg tttgccgcca taatcggcgt
    18661 aaagatgaga gatttgcagc atctgcgcct ccttttattg cacgaagcgc gaggtaacgt
    18721 actggctgta atcattcgct acagccggga ccttgccctg ctctttcaaa aactgcgcgg
    18781 tgtcgatgat cgctttgttc accggtccgg tcagttctgc cgtttgttgc tgcggcgtca
    18841 gataggtatt ccccttcacc agccccggaa cgtcaccttc aggcacgccg cttaaacgcg
    18901 ccagtttgct gatgttttcc ggctgtttca gccacacgtc tgggttagca atgtacggtt
    18961 gctgagcatc gatggcgctt ttagcgaacg ctttcacgac ctcaggatgt ttctcggcaa
    19021 aatctttgcg caccacccag acgtccagcg ttggcgcgcc ccactgcccg acctgttcag
    19081 aatcggtcaa caccttgccg tctttttcca gggcgttaac cgccggtgcc cagacataag
    19141 caccatcaat atctcctcgc tgccaggcag cgataatcgc gggcggctgc aggttcacaa
    19201 tctccacttg cccgggttta atgccccagt gtttcagtgc cgccagcagg ctgtagtggg
    19261 tggtggagat aaacggtacg gcgatgcgtt tgccaatcag atcttccggt ttgctgatag
    19321 ttttctttac caccagcgct tcggagttac ccagttttga cgccagcaag aagacttcaa
    19381 tcgacacctg ttggctggct gcaaccgcta acgggctgga accgaggttg ccgatttgca
    19441 cgtcgcctga agccagcgcc cgcacgatgc tggctccgct gtcaaactta cgccagtcca
    19501 cggttgctcc gctttcttta gcaaaggtgt tgtcggcctg agccactttc gccggttcgg
    19561 ctgaggtttg atacgccacg gtgacgttca ccgcctgtgc ctgaaaagcg atgaatgcca
    19621 gtgcggcaag aagtgtgtta cgcgatgaaa ttgccatgat tgtctgctcc cctgtcttgt
    19681 tatgggagca gtattcagga ataaaaacat tcattaaaag aattagtcgt tatcgcacag
    19741 atgattttat tcttagcaaa aaaacggcta aggaaagatt aaatatgcaa ttactccgtt
    19801 ctaacaattg ggaaaattac tacacttcat tttagtgatg cataaac
//
LOCUS       DACAOP010000087        19402 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.087, whole genome shotgun sequence.
ACCESSION   DACAOP010000087 DACAOP010000000
VERSION     DACAOP010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19402
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.087"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..871)
                     /locus_tag="IT892_003383"
     CDS             complement(<1..871)
                     /locus_tag="IT892_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020240475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HAP3136566.1"
                     /translation="MKSRYITPVVTIFDEQGRIDPEQNTQVYDFIKNHVSGFVVMGST
                     GEFFSLNMENARQMIKTCSEFSRGDMKVYAGASRMDVNESISLANYAWEQGLDGVMII
                     SPYYFPLDDEAIFDFYSTIASQTPAHIFIYNFPERTGYSVSPEICLRLADKYPNIIGM
                     KDTVPDAFHTAQVINTVKKNIPHFEVYAGYDNNFAHNILSGGDGCIGGLSNIVPEFFA
                     SWMQAFTNDDLLAVAQHQQIVDQLMAVYSVNSPFIPTFKKALQLKGVIQSERCSSPFN
                     ILDDIQSRRLQEIL"
     gene            1200..1979
                     /locus_tag="IT892_003384"
     CDS             1200..1979
                     /locus_tag="IT892_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAP3136567.1"
                     /translation="MEHKPTIRVLEILEALAAENQGVSLTHLSEKTGILKGTIFPILK
                     TLVEQRYISYDANTQLYNLGISCSILSRAFLDRSYWLKMVYKEMNNIVKECNEVCQMG
                     ILDGADVLYINKVQAAQTVQLVSHIGTRLPAIYSALGKAIICEYSDQQIQQLYPDGFV
                     PMTSYSVTTLEQLRQQLEDARVNGYAFDNREINEETVCYAVALKQRNKTLAAISISIP
                     VFRATKEKIADVTRILLNARSRIEQELNTLQDINIGIDSHH"
     gene            complement(2056..2787)
                     /gene="rlmB"
                     /locus_tag="IT892_003385"
     CDS             complement(2056..2787)
                     /gene="rlmB"
                     /locus_tag="IT892_003385"
                     /EC_number="2.1.1.185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAP3136568.1"
                     /translation="MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALE
                     SQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIASLDQPFLLILDG
                     VTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
                     MRMLQEENIWIVGTAGEADHTLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPM
                     AGSVSSLNVSVATGICLFEAVRQRS"
     gene            complement(2968..5409)
                     /gene="rnr"
                     /locus_tag="IT892_003386"
     CDS             complement(2968..5409)
                     /gene="rnr"
                     /locus_tag="IT892_003386"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418600.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAP3136569.1"
                     /translation="MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVEL
                     HIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVE
                     GRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEA
                     GVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNM
                     GTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDA
                     RDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVIPMLP
                     EVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQG
                     DQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQT
                     QRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLEL
                     PGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHF
                     TSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRAD
                     EATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYY
                     RFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTAHE
                     KAKKGDAGKKGGKRRQVGKKVNFEPDSAFRGEKKPKPKAAKKDARKAKKPSAKTQKIA
                     AATKAKRAAKKKVAE"
     gene            complement(5448..5873)
                     /gene="nsrR"
                     /locus_tag="IT892_003387"
     CDS             complement(5448..5873)
                     /gene="nsrR"
                     /locus_tag="IT892_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide-sensing transcriptional repressor
                     NsrR"
                     /protein_id="HAP3136570.1"
                     /translation="MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVK
                     IINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPAC
                     RLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE"
     gene            complement(6078..7376)
                     /gene="purA"
                     /locus_tag="IT892_003388"
     CDS             complement(6078..7376)
                     /gene="purA"
                     /locus_tag="IT892_003388"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAP3136571.1"
                     /translation="MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTL
                     VINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSE
                     ACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
                     KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDF
                     VMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGA
                     GPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLD
                     VLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGL
                     PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA"
     gene            complement(7480..7677)
                     /locus_tag="IT892_003389"
     CDS             complement(7480..7677)
                     /locus_tag="IT892_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 domain-containing protein"
                     /protein_id="HAP3136572.1"
                     /translation="MNSTIWLALALVLVLEGLGPMLYPKAWKKMISAMANLPDNILRR
                     FGGGLVVAGVVVYYMLRKTIG"
     gene            complement(7759..8763)
                     /gene="hflC"
                     /locus_tag="IT892_003390"
     CDS             complement(7759..8763)
                     /gene="hflC"
                     /locus_tag="IT892_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HAP3136573.1"
                     /translation="MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNK
                     PLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSR
                     YYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
                     GTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTE
                     VSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGD
                     AEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
                     "
     gene            complement(8766..10025)
                     /gene="hflK"
                     /locus_tag="IT892_003391"
     CDS             complement(8766..10025)
                     /gene="hflK"
                     /locus_tag="IT892_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HAP3136574.1"
                     /translation="MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDI
                     FRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRVVTIAAAAIVIIWAASGFYTIKE
                     AERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVE
                     MNVQYRVTNPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQR
                     ELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQ
                     PRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPEITRERLYIETMEKV
                     LGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGASNLLRLPPASSSTTSGASN
                     TSSTSQGDIMDQRRANAQRNDYQRQGE"
     gene            complement(10111..11391)
                     /gene="hflX"
                     /locus_tag="IT892_003392"
     CDS             complement(10111..11391)
                     /gene="hflX"
                     /locus_tag="IT892_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAP3136575.1"
                     /translation="MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQV
                     ITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVID
                     RTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
                     ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRIT
                     EARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQ
                     ATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEE
                     NKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKE
                     WMEEDGSVSLQVRMPIVDWRRLCKQEPALIDYLI"
     gene            complement(11468..11776)
                     /gene="hfq"
                     /locus_tag="IT892_003393"
     CDS             complement(11468..11776)
                     /gene="hfq"
                     /locus_tag="IT892_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HAP3136576.1"
                     /translation="MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVI
                     LLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
                     "
     gene            complement(11862..12812)
                     /gene="miaA"
                     /locus_tag="IT892_003394"
     CDS             complement(11862..12812)
                     /gene="miaA"
                     /locus_tag="IT892_003394"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAP3136577.1"
                     /translation="MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSA
                     LIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIP
                     LLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARI
                     HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRF
                     HQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATR
                     QLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG"
     gene            complement(12805..14652)
                     /gene="mutL"
                     /locus_tag="IT892_003395"
     CDS             complement(12805..14652)
                     /gene="mutL"
                     /locus_tag="IT892_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAP3136578.1"
                     /translation="MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDI
                     DIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASI
                     SSVSRLTLTSRTAEQQEAWQAYAEGRDMNVTVKPAAHPVGTTLEVLDLFYNTPARRKF
                     LRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGT
                     AFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQAC
                     EDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQL
                     ETPLPLDDEPQPAPRAIPENRVAAGRNHFAEPAAREPVAPRYTPAPASGSRPAAPWPN
                     AQPGYQKQQGEVYRQLLQTPAPMQKLKAPEPQEPALAANSQSFGRVLTIVHSDCALLE
                     RDGNISLLSLPVAERWLRQAQLTPGEAPVCAQPLLIPLRLKVSAEEKSALEKAQSALA
                     ELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLM
                     SEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE"
     gene            complement(14662..15999)
                     /gene="amiB"
                     /locus_tag="IT892_003396"
     CDS             complement(14662..15999)
                     /gene="amiB"
                     /locus_tag="IT892_003396"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiB"
                     /protein_id="HAP3136579.1"
                     /translation="MMYRIRNWLVATLLLLCTPVGAATLSDIQVSNGNQQARITLSFI
                     GDPDYAFSHQSKRTVALDIKQTGVIQGLPLLFSGNNLVKAIRSGTPKDAQTLRLVVDL
                     TENGKTEAVKRQNGSNYTVVFTINADAPPPPPPPPVVAKRVETPAVVAPRVSEPARNP
                     FKTESNRTTGVISSNTVTRPAARATANTGDKIIIAIDAGHGGQDPGAIGPGGTREKNV
                     TIAIARKLRTLLNDDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNR
                     SATGASVWVLSNRRANSEMASWLEQHEKQSELLGGAGDVLANSQSDPYLSQAVLDLQF
                     GHSQRVGYDVATSMISQLQRIGEIHKRRPEHASLGVLRSPDIPSVLVETGFISNNSEE
                     RLLASDDYQQQLAEAIYKGLRNYFLAHPMQSAPQGATAQTASTVTTPDRTLPN"
     gene            complement(16018..16479)
                     /gene="tsaE"
                     /locus_tag="IT892_003397"
     CDS             complement(16018..16479)
                     /gene="tsaE"
                     /locus_tag="IT892_003397"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAP3136580.1"
                     /translation="MMNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTF
                     SRGFLQALGHQGNVKSPTYTLVEPYTLDNLMVYHFDLYRLADPEELEFMGIRDYFAND
                     AICLVEWPQQGTGVLPDPDVEIHIDYQAQGREARVSAVSSAGELLLARLAG"
     gene            complement(16451..17998)
                     /gene="nnr"
                     /locus_tag="IT892_003398"
     CDS             complement(16451..17998)
                     /gene="nnr"
                     /locus_tag="IT892_003398"
                     /EC_number="4.2.1.136"
                     /EC_number="5.1.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HAP3136581.1"
                     /translation="MTDHTMKKNPVSIPHTVWHADDIRRGEREAADALGLTLYELMLR
                     AGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARLATAVGIEVTLLAQESDKPLP
                     EEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGLQQAPRESISQLIDHANSH
                     PAPIAAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLTGKARDVTGQLHFDSLG
                     LDSWLAGQETKIQRFSAEQLSHWLKPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEA
                     ALRAGAGLVRVLTRSENIAPLLTARPELMVHELTMDSLTESLEWADVVVIGPGLGQQE
                     WGKKALQKVENFRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIES
                     DRLHCAKRLVQRYGGVAVLKGAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGA
                     LLGQKLSPYDAACAGCVAHGAAADVLAARFGTRGMLATDLFSTLQRIVNPEVTDKNHD
                     ESSNSAP"
     gene            17997..19136
                     /gene="queG"
                     /locus_tag="IT892_003399"
     CDS             17997..19136
                     /gene="queG"
                     /locus_tag="IT892_003399"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAP3136582.1"
                     /translation="MSEPLDLNQLAQKIKQWGLELGFQQVGITDTDLSESEPKLQAWL
                     DKQYHGEMDWMARHGMLRARPHELLPGTLRVISVRMNYLPANAAFASTLKNPKLGYVS
                     RYALGRDYHKLLRNRLKKLGEMIQQHCVSLNFRPFVDSAPILERPLAEKAGLGWTGKH
                     SLILNREAGSFFFLGELLVDIPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARR
                     CISYLTIELEGAIPEELRPLMGNRIYGCDDCQLICPWNRYSQLTTEEDFSPRKPLHAP
                     ELIELFAWSEEKFLKVTEGSAIRRIGHLRWLRNIAVALGNAPWDETILTALESRKGEH
                     PLLDEHIAWAIAQQIERRNACIVEVQLPKKQRLVRVIEKGLPRDA"
     gene            complement(19119..19172)
                     /locus_tag="IT892_003400"
     CDS             complement(19119..19172)
                     /locus_tag="IT892_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136583.1"
                     /translation="MRFYFYSQAVDESGVTR"
BASE COUNT         4554 a         5378 c         4793 g         4677 t
ORIGIN      
        1 ataaaatttc ctgcaatctc cgggattgaa tatcatcaag tatattaaat ggtgaagaac
       61 accgttctga ttgaataacc ccctttaact gaagggcttt tttgaaagtg ggaataaaag
      121 gagaattcac gctgtaaacg gccattagtt gatcgactat ctgctgatgc tgcgcgactg
      181 caagtaaatc gtcattcgtg aatgcttgca tccaggaggc aaaaaattca gggacaatat
      241 tggataaacc accaatacag ccatctccac cagatagtat gttgtgggca aaattattgt
      301 catatcctgc atacacttca aaatgaggga tatttttctt tacggtattg ataacctgcg
      361 cagtatggaa agcatcaggg acggtatctt tcataccaat aatattggga tatttatctg
      421 ccagtcgtaa acaaatctct ggtgatacgc tgtacccggt tctctccggg aagttataaa
      481 taaaaatatg agccggggtt tggcttgcaa tcgtactgta gaaatcaaaa atagcttcat
      541 catccagagg gaaataataa ggactgatga tcatcacacc atccaatcct tgctcccagg
      601 cgtaattggc cagtgatatt gattcattga cgtccatgcg actggctccg gcataaacct
      661 tcatatcgcc tcgggaaaac tcactacagg ttttaatcat ttggcgggcg ttttccatat
      721 taagcgaaaa aaactcacca gtactgccca tcacaacaaa cccggacacg tgatttttaa
      781 taaaatcata aacctgagtg ttttgctcag gatcgattcg cccttgttca tcaaatatgg
      841 tgacaacggg ggttatgtaa cgacttttca tgcctacctc atcatagttt tattgttcat
      901 atatacaaac aacgttttta aatacaaact aaaatgagta tacccaacct cagaaataag
      961 tcaaatttag ccaatcacag aagtgataca cataagttat tgatagattt ggagtaatta
     1021 cgccagaggc ctgcataaaa aacaatcaca gttctttttt tatccgtttt atgaccagta
     1081 tcacgctaaa aaaggactga tggggtcaac agcaatcaag gaacgcgagg gggtttattt
     1141 acttgaatta taattctccc tagaatggtg cattactcat ggtaagggaa atagtcatta
     1201 tggaacataa gcctaccatc cgggtgttag agatactgga agcactggca gcggagaatc
     1261 agggtgtttc attaactcac ctttcggaaa aaacaggcat cctgaaagga acgatttttc
     1321 ccatcctcaa aacgctggtt gaacagcggt acatcagtta tgacgctaat acccagcttt
     1381 ataatctggg gatctcctgc tcgattctgt cccgtgcttt cctcgacaga tcgtactggt
     1441 taaaaatggt ttacaaagag atgaacaaca ttgtcaaaga gtgcaatgag gtttgtcaga
     1501 tggggatcct ggacggtgca gatgttttat atatcaataa ggtgcaggcg gcacaaaccg
     1561 tacaactggt ttcacatatt gggactcgtc tgcctgctat ctattctgcg ctgggaaaag
     1621 ccattatctg tgaatacagt gatcaacaaa ttcagcaact ctaccctgac ggttttgttc
     1681 ccatgacatc gtatagcgtt acgaccctgg aacaattgcg ccaacaactt gaggatgcca
     1741 gagtaaatgg gtatgcattt gataacaggg aaatcaatga ggagacggta tgttatgctg
     1801 ttgccttaaa acagcgaaat aaaacgcttg ccgccatcag catttcaata cccgtatttc
     1861 gtgcgacaaa agaaaaaatt gccgatgtca cgcgtatcct gctgaatgca cgttcgcgta
     1921 ttgaacagga actcaacacc ttacaggata tcaatatcgg tattgattcc caccattaag
     1981 ggtattttcc attcgaagcc cgatacgtaa aaattatcgg gctaacaaaa tatccattga
     2041 atggatagcg atgaactagc tgcgctggcg caccgcttca aataagcaaa ttccggtcgc
     2101 aaccgaaacg ttcagggaag aaacacttcc tgccattggg atgctgatca actcatcgca
     2161 atgttcacgg gtcaggcgac gcataccttc accttccgcg cccatcacca gcgccaggcg
     2221 tccggtcatt ttgctctgat agagtgtatg atctgcctcg cctgccgtac cgacgatcca
     2281 gatattctct tcctgcaaca tacgcatggt gcgcgcaagg ttagtcaccc gaatcagtgg
     2341 aacgctttct gccgcgccgc aggctacctt tttcgccgta gcgttgagct gtgcggagcg
     2401 atctttcggc acaatcaccg cgtgaacgcc agcagcgtcc gcgctacgca ggcacgcgcc
     2461 gaggttgtgc ggatcggtta caccgtcgag gatcagcagg aacggttgat cgagcgaagc
     2521 gatcagatcc ggcagatcgt tttcctgata ctgacgtcct ggcttcacgc gggcgataat
     2581 gccctgatgc acggcaccgt cgcttttctc gtcgagatat tggcggtttg ccaactggat
     2641 aaccacgccc tgagactcaa gggcgtgaat cagcggtaac agacgtttat cttcacggcc
     2701 ttttaaaata aagacttcct gaaaacgttc aggggcgcgc tccagcaggg cctgcactgc
     2761 gtggatgccg taaatcattt cgctcattaa tatactcgtt gtttacgttt tgcctgatgc
     2821 gctacgctta tcaggcctac atgatccctg caatgtattg aatttgcgtg attatgtagg
     2881 ccggataagg cgttcacgcc gcatccggca tgaacaaagc gcattttgtc agcaatctga
     2941 ccctcttctg tttgaagagg gtaatgatca ctctgccact tttttcttcg ccgcacgctt
     3001 cgctttggtc gctgcggcta ttttctgcgt tttcgccgat ggctttttcg cttttctcgc
     3061 gtctttcttc gccgctttcg gcttcggttt tttctcgccg cggaaggcgc tgtctggctc
     3121 aaagtttacc tttttaccga cctgacgacg cttgccgcct tttttgcctg catcgccttt
     3181 tttcgctttc tcgtgcgccg ttttaccgac gttgcgcggt gcgcgttcgc tggagatcag
     3241 gctaaagtcg attttgcgct cgtccatatt aaccgcttca acgcgaactt ccacgcgatc
     3301 gcccaggcga taagtctggc cgctggattc acccatcagg cgttgcccta cctggtcaaa
     3361 gcgatagtag tcattgtcca gcgaagagac atggaccaga ccatcaatga acaagtcgtc
     3421 cagacggacg aagaagccaa agccagtgac gctggaaatt acgcctttaa agacgttacc
     3481 tacctggtcg agcatgaagt cacacttcag ccagtcagct acatcgcgtg ttgcttcgtc
     3541 ggcacgacgt tccgccatcg aacagtgctg acccagttgc agcatctctt ccatcgaata
     3601 atggtagccg ccggtttcag tggtgttgcc ctgatgcccc tgctctttcg ccagcagata
     3661 tttaatggcg cggtgcagcg tcaggtcagg ataacgacga atcggcgaag taaagtgcgc
     3721 ataggactgc aatgccagac cgaagtgacc acggttttcc ggatcgtaaa tcgcctgttt
     3781 catcgagcgc agcagcatgg tttgcagcat ttctgcgtca ggacgatcgg caaccgactc
     3841 cagcagttcc gcgtagtcac gcggttccgg cttgttaccg cccggcaatt ccagccccag
     3901 ctccgccagc actgaacgga aagaggtaat tgcttcggtg ctcggcttgt cgtgaatacg
     3961 gaacagtgcc ggttctttcg ctttctcaac gaaacgcgcc gccgagatat tcgccagaat
     4021 catgcactct tcaattaact tgtgggcgtc gttacgctga gtctgttcga tacgttcaat
     4081 acggcgttca gcgttgaaaa tgaacttcgc ttcttcgctc tcaaatgaga tccctccgcg
     4141 ttcttcacgg gctttatcca gcactttata gaggttatgc aactcttcga gatgcttaac
     4201 cagcggggcg tactgctcgc gcagatcctg atcgccctgc agaatatgcc agactttggt
     4261 gtaggtcaga cgcgcgtgag agctcatcac cgcttcgtag aatttgtagc cagtcaggcg
     4321 gcctttcgac gaaaccgtca tctcgcacac catacacagg cggtctacct gcgggttgag
     4381 cgaacacagg ccgttagaga gcacttccgg cagcatcggg ataacctgcg aagggaagta
     4441 caccgacgta ccacggttac gcgcttctct gtccagcggt gttggcggac gcacatagta
     4501 gctgacgtcg gcaatcgcga cccataaacg ccagccgccg ccgcgttttt tctcacagta
     4561 aactgcatcg tcaaagtcac gggcgtcttc gccatcaatg gtgaccagcg gtaaatcgcg
     4621 caaatcgaca cggcccgctt ttgcttcttc cggcacttct tctttcagcc cggcaacctg
     4681 ttgctcaaca gcctgcggcc agatatacgg aatttcatgg gtacgcagag cgatatcaac
     4741 cgccatgccg gtgcccatat tgtcgccaag tacttcgacg attttaccca ccgctttggt
     4801 acggcgagtc gggcgttggg tcagttcaac caccaccaca aagcccatcc gcgcgcccat
     4861 gatctgatcg ggcgggatta aaatatcgaa gctcagacgg ctgtcgtcag gaaccacaaa
     4921 gccgacaccc gcttcggtaa agtagcggcc aacaatctgg ctggtttttg gcaccagtac
     4981 gcggacaata cgcgcttcac gacgaccttt acggtcagcg cccagcggct gcgccagcac
     5041 ctgatcgcca tgaatgcagg ttttcatctg ctcgctggag agatacaaat catctttacg
     5101 cccttcaacc cgcagaaagc cgtagccatc acggtggcca ataacggtac ctttcaccag
     5161 gtcgaggcgt tccggcagcg catagcactg acgacgagtg aagaccagtt gaccatcgcg
     5221 ctccatcgcg cgcaggcggc gacgcaggcc ttcaagctgc tcttcgcctt caatgtgcag
     5281 ttctaccgcc agctcatcac ggctggccgg tttttcacgt ttggttaaat gttcgaggat
     5341 aaattcccga ctagggatgg gattcgcgta tttttcagct tcgcgttcct ggaaaggatc
     5401 ttgtgacatc tcggttcctc cgttgtcatc tctgatgaag attttcgtca ctccaccagc
     5461 aataatttat aaagcggttg attctcttca accaaatcgg caagcgtgta gttatccagt
     5521 tccgtaagaa aactttgcac ggccttagaa agtgcctgtt tcaaccgaca ggcaggtgta
     5581 atgtggcaaa actcactgct gcaattcacc agcgataagg gctccagctc gcgcaccaca
     5641 tcaccaatac gtatcgcact cgccggttta cccagacgaa tgccgccatt ttttccacga
     5701 acagcagtca cgtagccggc acgactaagt tgattgatta ttttgaccat atgattacgg
     5761 gagacgccgt agacgtcagt cacttcagaa atactggtca tccgcccttc tggcaatgac
     5821 gccatgtaga tcagcgcacg taatccgtaa tcagtgaaac tcgttaactg cacatcaacc
     5881 tcaaaaggga aatcgggaaa aaatacattt atattgatga taaaccagcc acaagctgtg
     5941 tcgctaattt atttcagttc ggggaaggaa aaaagcgagg atttaacact gtgtcggata
     6001 gcgtaatggc ttacccgaca cagcaatgta tcacactgtt agcccggcag gcaaaatatc
     6061 tgccaggcgt accagaatta cgcgtcgaac ggatcgcgca gaatcatggt ttcagtacga
     6121 tccggaccgg tagagatgat atcgatcggc acaccagtca gctcttcaat acgcttgatg
     6181 tagttcagcg ccgcctgcgg cagaccgcta cgatctttca cgccgaaggt ggattcagac
     6241 cagcccggca tggtttcgta aatcggctct acacctttcc agtcgtcagc tgccagcgga
     6301 gtggtagtca cttcgcgacc atccggcata cggtaagcca cgcagagttt aacctctttc
     6361 aggccatcca gaacgtccag tttagtcagg cagaagccag acagggagtt cagctgtacc
     6421 gcacgacgaa cggcaacggt gtccagccag ccggtacgac gacgacgccc cgtagttgcg
     6481 ccgaattcgt taccctgctt gcagaggaac tcgccagttt catcaaacag ttcggtcggg
     6541 aacggacctg cacctacacg agttgagtaa gctttgagga tacccagaac ataatcaaca
     6601 taacgcgggc ccaggccgga accggtcgcc acgccaccag cagtggtgtt ggaagaagtt
     6661 acgtacggat aagtaccgtg gtcgatatcc agcagcgtac cctgcgcacc ttcaaacatg
     6721 acgaaatcgc cacgctgacg cgcctggtcg agcaggtcag aaacgtcaac caccatagaa
     6781 gtcaggatgt cggcaactgc catcgtatca tccagaactt tctggtaatc aaccgcttca
     6841 gctttgtagt agttaaccaa ctggaagttg tgatattcca tcacttcttt cagtttttca
     6901 gcgaaggttt ctttgtcgaa aaggtcgcca acacgcagac cgcgacgtgc tactttatct
     6961 tcataagcag gcccgatacc acgaccggtt gtgccgatcg ctttcgcgcc acgcgctttc
     7021 tcacgcgcgt tatccagcgc aacgtgataa tcaaggatca gcggacatgc ttcagacagc
     7081 agcagacgct cacgaacggg gatgccacgg tcttccagtt ctttcatctc tttcatcagc
     7141 gcggccggag acagcacaac accgttaccg atgatgctgg ttacattctc gcggagaata
     7201 cctgatggaa taagatggag aacggttttt tcaccgttga ttacgagagt atggcctgcg
     7261 ttgtgaccgc cctggtagcg tacaacatat ttagcccgtt cagtcagaag atcgacgatc
     7321 ttacctttac cttcgtcacc ccattgggtg cccagtacga cgacgttgtt acccattttt
     7381 caaaatcacc gtttgcttaa aaatggattc taccatcgct ttttcagagt tacagcactt
     7441 tttgcactca aaaatgacct cgatcagtct gttttttgtt cagccaatcg ttttcctcaa
     7501 catgtagtag accacaacgc ccgcaaccac aagtccaccg ccaaaacgac gtaaaatatt
     7561 atcgggcaaa ttggccatcg cagagatcat cttcttccat gccttcgggt aaagcatcgg
     7621 ccctaaacct tccagtacca aaaccagggc aagcgccagc cagattgtcg aattcattca
     7681 ttatccttat agaaaaagaa aaccaccgac atccctgagg atgcggtggc tttattgacc
     7741 tgtaccgcag tcgttatatt aacgcgttgc ggaagtcggc gtcttcatgt agcggaagaa
     7801 atcgctatcc gggctcatga ccatcacgtc ctgattgcca gagaagctgt tctcataagc
     7861 acgcaggcta cggatgaatg cgtagaagtc cggatcttta ctgaatgcat cagcaaacag
     7921 tttggctgct tcggcatcgc cttcaccacg catgatgcgg ccctgacgct cagcttctgc
     7981 cagcgttctg gtcacttcat agtcggcagt cgcgcgcagt ttttccgctt cttcctgacc
     8041 ttgtgaacgg tgacgacgcg ctaccgcttc acgctcggcg cgcatacggt tgtagatcgc
     8101 ttcagacact tcggtcggca ggttgatctg cttgatacgc acatcgacaa cttcaatacc
     8161 cagcgccgcc atactgttcg ggttgatgac cggaactttg cccttcgtct cagccgttac
     8221 gcgctctgcc gcttcggcaa tggcgttatc tgccgccggg gtagtaactt catcttctgt
     8281 acccgcagaa ccggagttca gcgcgtcacg tacttcgagg gtcagacgac cacgggaatc
     8341 ggtgacgatg tctttcacgt ccaggcgacc aatttcagaa cgcagacggt cagagaactt
     8401 acgtttcaac agcacttccg cttgcgaaat gtcgccacca cccgttgcca ggtagtaacg
     8461 gctgaaatcg ctgatgcgcc atttgatgta agagtcgacg atcaggtctt tcttctcttt
     8521 ggtcacaaag cggtcggcct ggttgtccat ggtctgaata cgtgcgtcga gcattttcac
     8581 cgtttcaatg aacggtatct tgaaatgcag acccggctca taaaccagag gtttgttgtc
     8641 atcgtcacgc agtaccttac caaaacgcag cgtaataccg cgctcacctt ctttgacgac
     8701 aaagacagac atgtaaagca ctaccagcac gatgatgata atcgcgataa ctgacttacg
     8761 catcgttatt ccccctgacg ctggtagtcg ttacgctgcg cgttggcgcg gcgttggtcc
     8821 ataatatcgc cctgactggt ggacgacgtg ttgcttgctc cactggttgt ggaggaagag
     8881 gctggcggca gacgcagcag attgctggca ccgttatcgc tcttcgccgc aggggcgtta
     8941 ccacctttca gcatctggtc taacggcaga accatcaggt tgccaccttt atcgttaacc
     9001 agcactttgc gggtgttacc caacactttt tccatcgtct cgatatacag acgctcgcga
     9061 gtaatttccg gcgcggcttt atattccggc agaagtttag caaagcgcgc cacttcaccc
     9121 tgagcttcca ggatggtctg ggccttgtac gcacgcgcct cttcgaggat acgttgcgcc
     9181 tgaccgttcg cacgcggctg aacttcgttg gtatacgctt ctgcttcacg aatgtattgc
     9241 tgttcgtttt cacgcgcggc aatcgcatcg tcaaacgccg cttttacttc ttccggcgga
     9301 cgagcagcct ggaagttgac gtccagcagc gtgataccca tgtcatacgg acgaatcgtc
     9361 tcttccagtt cgcgctgagt atcgctacga atcacggtac gaccttccgt cagaatgcgg
     9421 tccatggtgt atttaccgat aactccacgc agggcgctgt cggtagcctg acgcaggctg
     9481 tcatccgggc tggtcacgct atacagatat ttttccggat tggtgacgcg gtactgcacg
     9541 ttcatctcaa cgcgcactac gttctcgtcc gacgtcagca tcacaccaga agcggccagt
     9601 tcacgcacgg cttccacgtt caccggtttg acttcgtcga taaacgtcgg tttccagttc
     9661 agacccggct caaccagatg gctgaattta ccaaagcgtg ttaccacgcc gcgttcggct
     9721 tctttaatgg tatagaaacc actggccgcc cagataatga caatcgctgc cgctgcgatg
     9781 gtaacgacac gaccgccaag ctgcgggcgc gggccttgcg atgaactgcc accgccagat
     9841 ccggtgcctt taccgccgcc cagaccaccg agctttttgc tcagtttgcg gaagatatca
     9901 tctaaatcag gtggcccttg atcgcgaccg cctttgtttc catttccctc agagttgccg
     9961 ccaggtttgc tgcttcccca cgggtcgcgg tcttgtccgt tattaccggg ctgattccac
    10021 gccatgtttg tgctccatat ttgttatgcg gtgatccctg ttgtctttcg acgccagagg
    10081 atatgactcc acgcttcaga cgctacgccg ttagatcagg taatcgatca acgccggttc
    10141 ttgtttacag aggcgacgcc agtcaacgat cggcatacga acttgcagac ttacgctgcc
    10201 gtcctcctcc atccactctt tttctattgc ctgaagctga taaaaacgac ttctcagacg
    10261 cccttcctgc ggtggcagac gcaatgtatg ctgcgccacc tcgccggaaa gccgctccgt
    10321 caaagcctga aaaagctgtg gtatccccgc tccggtctgt gcggaaagcc agacacggat
    10381 cggtttgttc tcttcgtccc gatcaatacg cggttcgaaa tcttccagca tatcgatctt
    10441 gttcatcacc agcagggttg ggatctcgtg agcgtcgatc tcttcaagaa ccgtattcac
    10501 cgcttcgatg ttttcttgta cacgcacatc cgccgcatca atgacgtgca gcagtaatgt
    10561 ggcttgccgc gtctcttgta acgtggcttt aaatgccgcc accagatcgt gcggcaggtg
    10621 gcgaataaac cctacggtat ctgcaagtac ggtttcaccg acatctgcaa cgtcaatacg
    10681 ccgcaacgtc gggtcgaggg tggcaaacaa ctggtctgcc gcgtagaccc gcgcttcggt
    10741 gatgcgattg aaaagggtag atttaccggc gttggtatat cccaccagcg aaacagtagg
    10801 aacgtcggct ttgatacgcg attgccgccc ctgctcacgc tgcttttcaa ctctttccag
    10861 gcgtgactgt atctgcacga tgcgattacg caacaaacga cggtcggttt cgagctgggt
    10921 ttcacccgga ccacgcaaac ctatcccgcc tttctgtctt tcaaggtggg tccagccacg
    10981 caccaggcgc gtagccagat ggcgcagctg cgccagctca acctgcaact taccctcatg
    11041 ggtacgcgca cgttgggcga aaatatctaa aataaggccg gtgcggtcga taacacgaca
    11101 ctcgcacaaa cgctccaggt tacgctcttg cgccgggctc agggcatggt caaaaagaac
    11161 gaccgaagca cccgtcgctt tgacagcttc cgcaatttca actgctttac cttcacctac
    11221 aaaatacttt gggtgcggcg ctttacggct accggtaatc acctgcaatg cttcgacacc
    11281 ggcggaagag accagagatt caaactcctg gaggtcttcc atatctttgt cttgcgtaaa
    11341 atagatgtgt accagtaccg cctgctcacc agcatcataa cggtcaaaca agcgtataac
    11401 cctctaaata gatcagcggg gaacgcagga tcgctggctc cccgtgtaaa aaaaacagcc
    11461 cgaaacctta ttcggtttct tcgctgtcct gttgcgcgga agtattctgc gcgctgctac
    11521 catgatggta gttactgctg gtaccgccac cggcgttgtt actgtgatga gaaaccgggc
    11581 gagacgggac aacagtagaa atcgcgtgct tgtaaaccat ctggctgacc gtgtttttca
    11641 acaggatcac gaactgatca aaagactcga tttgcccttg cagcttaata ccattcacca
    11701 aataaataga aactggaaca cgttcccgac gcagtgcgtt caggaacgga tcttgtaaag
    11761 attgcccctt agccattctc tcttttcctt atatgcttat ttgtactttg aacctttcga
    11821 ttctgaaaaa attgcgcacg atacgtctca attgtacaca ttcagcctgc gatagcacca
    11881 acaacctgta atacttcgtc acgcgcctgt tctggttttt cactgtcaag ccagtgaacc
    11941 ccttcccaac cacgcagcca ggttatctgc cgcttcgcca actgtctcgt ggcgcaaaca
    12001 cctcgataaa ccatttcatc gtatgagatt tcgccttcaa ggtaagacca catctggcga
    12061 taacccacgc aacgaatgga aggcaagtcc gtatgcaaat ctcctcgggc aaaaagcgcc
    12121 cggacttctg cttcaaaacc tgaagccaac atctgatgaa aacgctgctc aatgcgttga
    12181 tggagcagtt cacggctcgc cggggcgatg gcgaactgat gcacctgata cggtagagcg
    12241 tctcctgacg tttgcgtcag ttccgttaaa gttttacccg aaatgaaaaa aacttccagt
    12301 gcccgggaaa gcctttgtgg atcatttgga tgaatccttg ctgccgcaac cggatctacc
    12361 tcctgaagtt gacgatgcaa tgactcccaa ccttgctctg ccgcctgttg ctcaattctg
    12421 gcccgtactt ccgggtctgc cgacggtagc ggcgacaacc cttccagcaa tgccttgaaa
    12481 tacaacatcg taccgcccac taacagtggg atccgccccg ccgcggtgat atcggccatt
    12541 tccgccagcg catcgcggcg aaaatcagca gccgagtaag cctgcgacgg atcgcgaata
    12601 tccagcaatc ggtgcggcgc ggcgagtaac tcttcagcgt tcggcttcgc cgtcccgata
    12661 tccatccctt tgtaaataag ggcagaatca acgcttatca actctactgg taaaatttta
    12721 cgcagctcaa tggctaacgc cgttttaccg gaggccgtcg gccccatcaa aaaaatcgcc
    12781 ttaggcaggc tcgccttact gatatcactc atctttcagg gcttttatcg ccggatgtaa
    12841 atcaacagat tgtaacagac cacccggcgg cgttttcaca agttgcggac ataaccgttc
    12901 cacgtccgcc agcagggtta tggcctgtgc cattgaccac tgcgcatgtt cgctcatcag
    12961 atttcgtgca atccactgcg caatattgcc aggttcgaat acggactgct tcgccaggta
    13021 gcctatcagt tcaggaatca agatttgtaa attttgttgg cgtaagggta aaggcacggc
    13081 cctgatggtc acatgctgtg catctgactg gaaatcaata cccaattccg ccagggcaga
    13141 ctgcgctttt tctaatgccg atttttcttc ggcagaaact tttagccgca acggaatcag
    13201 cagcggctgg gcgcaaacgg gcgcttcacc cggcgtcaat tgtgcctgac gtagccaacg
    13261 ttctgccact ggcaaggata aaagtgaaat gttgccatcg cgctccagca acgcacagtc
    13321 ggaatggacg atagtcagta cccgaccaaa actctgactg ttcgccgcaa gtgcaggttc
    13381 ctgcggttcc ggcgctttta atttttgcat cggcgcgggc gtttgcaaaa gctggcgata
    13441 cacttcacct tgctgtttct ggtagcctgg ctgcgcattc ggccaggggg cagccggacg
    13501 actgcctgat gctggcgcag gagtgtagcg cggagctacc ggctcacgag ctgccggttc
    13561 tgcaaagtga ttgcgccccg ccgccacgcg gttttccggg atggcacgcg gtgcgggttg
    13621 tggttcatcg tccagcggta gcggcgtttc cagttgctgc tgtagcacgc tcagcacgcc
    13681 ctgatagata aagtcatgca ccagacgcga ctgatggaaa cgcacttcgt gtttggcggg
    13741 gtgtacgttg acgtccacct gatgcgggtc gatctccaga tacaacacaa acgccggttg
    13801 ttgatcggcc cccagtttgt cttcgcaggc ctggcggatc gcatgattga tcaggcgatc
    13861 gcgcatcatg cgaccattca cgtagcaata ctgaatttcc gccagtgcgg gcgtagtgtg
    13921 atttggatcg gccacccagc cgcgcagggt gagatcgccg tgttgccatt caatcgccag
    13981 cgcttgttcg agaaaagcgg tgccgcaaat cgcgcctaag cgccgttctt tttgcccgcc
    14041 ttccggcact gcgcggtact gacgcacaat tttaccgtta tgcgacaggt tgatcgtgac
    14101 gtcgaaacgc gccagcgcaa tgcggcggat gatctcatca atgtggttaa attcggtttt
    14161 ctcggtgcgc aggaatttgc gccgcgccgg ggtgttgtag aacagatcca gcacctccag
    14221 cgtcgtcccc acaggatgcg ccgccggttt taccgtcacg ttcatatcgc gcccttcggc
    14281 ataggcctgc caggcttcct gctgttctgc ggtgcgtgaa gtgagcgtca ggcgggaaac
    14341 cgaactgata ctcgccagcg cctcaccgcg aaagcccagg ctgataatgg cttcgagatc
    14401 gtccagagag gcgattttac tggtggcatg acgcgccagc gccagcgcca gctcgtcttt
    14461 tttgataccg cagccgttat cacgaatgcg gataagtttc gccccaccgc gttcgatatc
    14521 aatatcgata cgtgtcgcac ctgcatcgag gctgttttcc accagttctt tgactaccga
    14581 cgcaggtcgc tcgaccacct cacctgcggc aatctggttc gccagttgtg gcggtaagac
    14641 ctgaattggc atcaatcgtc cttagtttgg cagcgtgcga tctggcgtcg tcaccgtact
    14701 ggccgtttgt gccgttgccc cctgcggcgc agattgcatc ggatgcgcaa ggaaataatt
    14761 gcgcaggcct ttgtaaatgg cttctgccag ctgttgttgg taatcgtcgc tcgccagcaa
    14821 acgttcttcg ctgttgttgc tgataaaacc ggtttcgacc agtactgatg ggatatccgg
    14881 cgaacgcaga acgccgagac tcgcgtgttc tggtcggcgt ttatgtattt cgccaatgcg
    14941 ttgcaactga ctgatcatac tggtcgctac atcataccct acccgctggg aatgaccgaa
    15001 ctgtaaatcc agcaccgcct ggcttaaata ggggtcagac tgactgttcg ccagcacatc
    15061 acccgcccca cccagcagct ccgactgttt ctcgtgctgc tccagccagc tggccatttc
    15121 gctgttggcg cgacggttag agagcaccca tacggaagcg ccagtcgcac tgcggttcgg
    15181 tgcggcatca gcgtgaatcg acacgaggaa attggcgttt tgcttacgtg ccacatcact
    15241 gcgccccatc accgagataa agtaatcccc gtcacgggtt aaaacgccct taaacatcgg
    15301 atcgtcattg agcaaagtac gcaatttacg cgcgatggcg atggtgacat ttttctcccg
    15361 cgtaccaccg gggccgatag cgccagggtc ctgaccgccg tgtccggcat caatagcgat
    15421 gataatttta tcgccagtgt tagccgtcgc gcgcgctgcc ggacgcgtta ccgtattact
    15481 gctgataaca cccgtagtgc ggttactttc cgttttaaac ggattgcgcg ccggttcgct
    15541 gacgcgcggt gcgacaaccg caggcgtttc aacgcgtttc gcaaccacgg gcggcggagg
    15601 aggaggtggc ggcgcatcgg cgttaatcgt aaagacgaca gtgtaattgc tgccattctg
    15661 ccgcttcacc gcttcggttt taccgttttc ggtaagatcg accaccagcc gtagcgtttg
    15721 tgcatcttta ggcgttccag agcgaatcgc cttcaccaga ttattgccgc tgaacaacaa
    15781 cggcagtccc tgaatcacgc ccgtttgttt gatatcgagc gccacggtgc gtttgctttg
    15841 atggctaaac gcataatcag gatcgccaat aaaactcaac gttatccgcg cctgttgatt
    15901 accgttagaa acctgaatat cagagagcgt cgcggcaccc accggcgtgc acagcagcag
    15961 cagcgtcgct accaaccaat ttctgatgcg atacatcatc ccgccacctt tcaaaggtta
    16021 accggctaaa cgcgccagca acaattcacc cgcagaggaa accgcactca cgcgcgcctc
    16081 acggccttgt gcctgataat caatgtgtat ttcgacatcc gggtcaggaa gaacacctgt
    16141 accttgttgt ggccactcca ccaggcagat ggcatcgttg gcaaaataat cgcggatccc
    16201 cataaactcc agctcctcgg gatcggcaag gcggtacaaa tcaaagtgat aaaccattaa
    16261 attgtcgagc gtatagggtt cgaccagcgt ataagtgggg cttttgacat taccctgatg
    16321 acccagagct tgtaaaaagc cccggctaaa ggtggtttta cctgcgccta aatcgccata
    16381 cagatagatt acggttgcgc catcgcaggc tttcgctacc cgctcgccca ggtctaatgt
    16441 tgcctgctca tcagggagcg gaattactcg attcatcatg gtttttatca gtcacttccg
    16501 ggttaacaat acgctgtagc gtggaaaaga gatcggttgc cagcatcccg cgcgttccaa
    16561 aacgcgccgc cagtacgtca gctgcagcac cgtgcgcgac acagcccgca caggcggcat
    16621 catacggcga cagtttttgc ccaagcaatg cgccaataat accagagagc acatcgccca
    16681 tgccgccgct cgccatgcct gcatttccgg catcaataat gcctaaagcg tcaggatggg
    16741 cggcgaccac ggttccggca cctttcagca ccgctacgcc gccataacgt tgtaccagac
    16801 gtttggcgca atgtaagcgg tcactttcaa tttcagcgac ggaacagcct aacaaccgtg
    16861 cggcctcgcc aggatgcggc gtgatcacgc gattgtgacg cttatcggga ttgattgcca
    16921 gcaggttcaa tgcatcggca tcccacaaca tcggtttgcg aaaattctca actttttgca
    16981 gtgctttttt cccccactct tgctggccca gaccgggacc aatcaccacc acatcggccc
    17041 attccaggct ttcggtaaga gagtccatcg tcagttcatg caccatcaat tccggtcgtg
    17101 cagtcagcag cggcgcaatg ttttcactgc gggtcagtac tcggactaaa ccagcaccag
    17161 cacgtagcgc cgcttccccc gtcatacgaa tagcccccgc cgtgccgtga tcgccaccga
    17221 taattaccag ccgcccgtga tcgcctttat gcgaagtcgg gcgacgcggt tttagccagt
    17281 gagaaagttg ttctgccgaa aaccgctgaa ttttcgtctc ctgacctgcc agccaactat
    17341 ccagccccag tgagtcaaaa tgcagttgtc cggtaacatc ccgcgctttt ccagtgagca
    17401 agcctggttt cagcgcaata aaagtgatgg tgtgatcggc gttgatcact gcgcctggcg
    17461 tagcgccggt ttcagccagc aggccggaag ggatatcaac cgccgcaatc ggcgcaggat
    17521 gggaattagc gtggtcgatt aactggctaa tggattcgcg gggcgcttgc tgcaagccgg
    17581 taccgagcag cgcatcaaca atcagatcta ccgattcggg ccagacaata ttcgaagcat
    17641 ggatctcgcc tcccgcgttt aaccatgctt cgcgtgccag cgcggcctct tccggcaacg
    17701 gtttgtcgct ctcctgggcc agcagcgtga cctcaatgcc gaccgctgtg gccagccgcg
    17761 cgaccacgta gccatcgccg ccgttattac catgaccgca cagcaccagc caatggcggg
    17821 cgtcaggata cgccgaacga cacacctgga atgcggcctc gccagcgcga agcatcagct
    17881 catagagtgt aagccccagc gcatctgccg cctcacgttc tccgcggcgg atatcgtcgg
    17941 cgtgccagac ggtgtgtggt atacttacgg ggtttttctt cattgtatgg tccgtcatgt
    18001 cagagcccct cgatctcaat cagttagcgc aaaaaattaa acagtggggg ctggaactgg
    18061 gctttcagca ggtaggtatt accgataccg atctcagcga gtccgagccc aaactgcaag
    18121 catggctgga caaacaatac cacggcgaaa tggactggat ggcacgtcac ggtatgctgc
    18181 gcgctcgccc ccatgagtta ttgcccggta cgctgcgcgt gatcagcgtg cggatgaatt
    18241 accttcctgc taacgccgca tttgccagca cgctgaaaaa ccccaaactc ggctatgtta
    18301 gccgttatgc gctgggccgt gactatcaca aacttctgcg caaccgactc aaaaagctgg
    18361 gcgagatgat tcagcaacat tgtgtttcgc tgaattttag accgtttgtc gattctgcgc
    18421 ctattctcga gcgcccgtta gctgaaaaag ctgggctcgg ctggacaggt aagcactcac
    18481 ttatcctcaa tcgcgaggcc ggttctttct tctttttagg cgaattgctg gtcgatattc
    18541 cgctgcccgt ggatcaacca gtcgaggaag gatgcggtaa atgcgtggcc tgtatgacga
    18601 tttgcccgac cggtgccatc gtcgagccat ataccgtcga tgctcgccgc tgtatctctt
    18661 atctcaccat cgaacttgaa ggggcgatcc cggaagagtt gcgaccgtta atgggaaacc
    18721 gtatttacgg ttgcgatgac tgccagctta tctgcccgtg gaatcgctat tcacaactca
    18781 ccacagaaga ggatttcagc ccgcgtaagc cgctacacgc accggaactc attgagttat
    18841 tcgcctggag cgaagagaag tttttaaaag tcacggaagg atcggcgatt cgtcgtattg
    18901 gtcacctgcg ttggctgcgt aatatcgccg tagcattagg caatgcccct tgggatgaaa
    18961 cgattttgac agcgctggaa agtcgtaaag gtgagcaccc acttctcgat gagcacatag
    19021 cgtgggcgat tgcgcagcaa atagagagac gaaatgcgtg catagtcgaa gtgcaattgc
    19081 cgaaaaaaca gcgtctggtt cgggtgattg aaaaagggtt accgcgtgac gcctgattca
    19141 tccacagctt gtgaataaaa ataaaaacgc attgcaattc aagacgaata aaatcgtcaa
    19201 gtgatcgact cgacaaaacg gaatcttaat ttttaactta tctatcaata ggttaaaaaa
    19261 atactattca ccgtgcgaag tttctttgaa attaagatta cagcctgagg ctgtggataa
    19321 ctctgtttac aagagtttgt cagagacaac gaaaaccagc aataacgcat cgcatcgctg
    19381 tggatatttt attgagagaa ga
//
LOCUS       DACAOP010000088        19161 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.088, whole genome shotgun sequence.
ACCESSION   DACAOP010000088 DACAOP010000000
VERSION     DACAOP010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19161
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.088"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            259..1491
                     /gene="mdtM"
                     /locus_tag="IT892_003401"
     CDS             259..1491
                     /gene="mdtM"
                     /locus_tag="IT892_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtM"
                     /protein_id="HAP3136584.1"
                     /translation="MPRFFARHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFN
                     ADVSLAPAAVSLYLAGGMALQWLLGPLSDRVGRRPVLITGALIFTLACAATMFTTSMT
                     QFLIARAIQGTSICFIATVGYVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAAL
                     MHFVHWKVLFAIIAVMGFISFVGLLLAMPETVKRGAVPFSAKSVLRDFRNVFCNRLFL
                     FGAATISLSYIPMMSWVAVSPVILIDAGGLTTSQFAWTQVPVFGAVIVANAIVARFVK
                     DPTEPRFIWRAVPLQLVGLALLIIGNLLSPHVWLWSVLGTSLYAFGIGLIFPTLFRFT
                     LFSNNLPKGTVSASLNMVILMVMSVSVEIGRWLWFNSGRLPFHLLAVVAGVIVVFTLA
                     GLLNRVLQHQAAELAEER"
     gene            1532..2812
                     /locus_tag="IT892_003402"
     CDS             1532..2812
                     /locus_tag="IT892_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HAP3136585.1"
                     /translation="MNKLIELRRAKMLALSLLLIAAATFVVTLFLPPNFWVSGVKAIA
                     EAAMVGALADWFAVVALFRRVPIPIISRHTAIIPRNKDRIGENLGQFVQEKFLDTQSL
                     VALIRRHEPALLIGNWFSQPENARRVGQHLLQIMSGFLELTDDARIQRLLKRAVHRAI
                     DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDKSRKFIAQQIVRWLESEH
                     PLKAKILPTEWLGEHSAELVSDAVNSLLDDISRDRAHQIRHAFDRATFALIEKLKNDP
                     EMAARADAVKSYLKEDEAFNRYLSELWGDLREWLKADINSEDSRVKERIARAGQWFGE
                     TLIADDALRASLNGHLEQAAHRIAPEFSAFLTRHISDTVKSWDARDMSRQIELNIGKD
                     LQFIRVNGTLVGGCIGLILYLLSQLPALFPLGNL"
     gene            2928..4079
                     /locus_tag="IT892_003403"
     CDS             2928..4079
                     /locus_tag="IT892_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418755.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase subunit D"
                     /protein_id="HAP3136586.1"
                     /translation="MSLVTDLPAIFDQFSEARQKGFLTVMDLKERGIPLVGTYCTFMP
                     QELPMAAGAVVVSLCSTSDETIEEAEKDLPRNLCPLIKSSYGFGKTDKCPYFYFSDLV
                     VGETTCDGKKKMYEYMAEFKPVHVMQLPNSVKDDASRALWKAEILRLQKTVEERFGHE
                     ISEDALRDAIALKNRERRALANFYHLGQLNPPALSGSDILKVVYGATFRFDKEALINE
                     LDAMTARVRQQWEEGQRLDPHPRILITGCPIGGAAEKVVRAIEENGGWVVGYENCTGA
                     KATEQCVAETGDVYDALADKYLAIGCSCVSPNDQRLQMLSQMVEEYQVDGVVDVILQA
                     CHTYAVESLAIKRHVRQQHNIPYIAIETDYSTSDVGQLSTRVAAFIEML"
     gene            4089..4856
                     /locus_tag="IT892_003404"
     CDS             4089..4856
                     /locus_tag="IT892_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136587.1"
                     /translation="MTYSIGIDSGSTATKGILLADGVITRRFLVPTPFRPATAITEAW
                     ETLREGLETTPFLTLTGYGRQLVDFADKQVTEISCHGLGARFLEPATHAVIDIGGQDS
                     KVIQLDDDGNLCDFLMNDKCAAGTGRFLEVISRTLGTSIEQLDSITENVIPHAITSMC
                     TVFAESEVISLRSAGVAPEAILAGVINAMARRSANFIARLSCEAPILFTGGVSHCQRF
                     THMLESHLGMPVQTHPDAQFAGAIGAAVIGQRQRKRA"
     gene            4853..5110
                     /locus_tag="IT892_003405"
     CDS             4853..5110
                     /locus_tag="IT892_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HAP3136588.1"
                     /translation="MKEYLFLFHSTVGVIQTRKALQAAGMTFRVSDIPRDLRGGCGLC
                     IWLTCPPGEEIQWVIPGHTESVYCQQDGGWRCIAHYGISPR"
     gene            5175..6035
                     /locus_tag="IT892_003406"
     CDS             5175..6035
                     /locus_tag="IT892_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418753.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HAP3136589.1"
                     /translation="MTKSISLSKRIFVIVILFVIVAVCTFFVQSCARKSNHAASFQNY
                     HATIDGKEIAGITNNISSLTWSAQSNTLFSTINKPAAIVEMTTNGDLIRTIPLDFVKD
                     LETIEYIGDNQFVISDERDYAIYVISLTPNSEVKILKKIKIPLQESPTNCGFEGLAYS
                     RQDHTFWFFKEKNPIEVYKVNGLLSSNELHISKDKALQRQFTLDDVSGAEFNQQKNTL
                     LVLSHESRALQEVTLAGEVIGEMSLTKGSRGLSHNIKQAEGVAMDASGNIYIVSEPNR
                     FYRFTPQSSH"
     gene            6103..7281
                     /locus_tag="IT892_003407"
     CDS             6103..7281
                     /locus_tag="IT892_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136590.1"
                     /translation="MPSPSHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMMAE
                     GSFSFSQLSWIASGNYAGYLAGSLLFSFGAFHQPSRLRPFLLASALASGLLILAMAWL
                     LPFILVLLIRVLAGVASAGMLIFGSTLIMQHTRHPFVLAALFSGVGIGIALGNEYVLA
                     GLHFDLSSQTLWQGAGALSGMMLIALTLLMPSKKHAITPMPLAKTEQQIMSWWLLAIL
                     YGLAGFGYIIVATYLPLMAKDAGSPLLTAHLWTLVGLSIVPGCFGWLWAAKRWWALPC
                     LTANLLVQAICVLLTLASDSPLLLIISSLGFGGTFMGTTSLVMTIARQLSVPGNLNLL
                     GFVTLIYGIGQILGPALTSMLGNGTSALAGATLCGAAALFIAALISTVQLFKLQVVTS
                     "
     gene            complement(7294..7848)
                     /gene="kptA"
                     /locus_tag="IT892_003408"
     CDS             complement(7294..7848)
                     /gene="kptA"
                     /locus_tag="IT892_003408"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418751.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HAP3136591.1"
                     /translation="MAKYNEKELADTSKFLSFVLRHKPEAIGIVLDREGWADIDKLIL
                     CAQKAGKRLTRALLDTVVATSDKKRFSYSSDGRCIRAVQGHSTSQVAISFAEKTPPQF
                     LYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKR
                     GLPFWQAENGVWLTSTVAVEFLEW"
     gene            8097..8780
                     /locus_tag="IT892_003409"
     CDS             8097..8780
                     /locus_tag="IT892_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136592.1"
                     /translation="MTQQGDAVAGELATEKVGIKGYLAFFLTIIFFSGVFSGTDSWWR
                     VFDFSVLNGSFGQLPGANGATTSFRGAGGAGAKDGFLFALELAPSVILSLGIISITDG
                     LGGLRAAQQLMTPVLKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEITERDKV
                     IFAAYQTSGSAIITNYFSSGVAVFAFLGTSVIVPLAVILVFKFVGANILRVWLNFEER
                     RNPTQGAQA"
     gene            8777..9238
                     /locus_tag="IT892_003410"
     CDS             8777..9238
                     /locus_tag="IT892_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136593.1"
                     /translation="MTTQVRKNIMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKI
                     TGLLDWVGHICEPVMALWGLPGEAATVLLAALMSMGGAVGVAASLATAGALTGHDVTV
                     LLPAMYLMGNPVQNVGRCLGTAEVNAKYYPHIITVCVINALLSIWVMQLIV"
     gene            9251..10423
                     /gene="iadA"
                     /locus_tag="IT892_003411"
     CDS             9251..10423
                     /gene="iadA"
                     /locus_tag="IT892_003411"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAP3136594.1"
                     /translation="MIDYTAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNIPS
                     DIVPDCTVVDLSGQILCPGFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVG
                     LLGTDSISRHPESLLAKTRALNEEGISAWMLTGAYHVPSRTITGSVEKDVAIIDRVIG
                     VKCAISDHRSAAPDVYHLANMVAESRVGGLLGGKPGVTVFHMGDSKKALQPVYDLLEN
                     CDVPISKLLPTHVNRNVPLFEQALEFARKGGTIDITSSIDEPVAPAEGIARAVQAGIP
                     LARVTLSSDGNGSQPFFDDEGNLTHIGVAGFETLLETVQVLVKDYDFSISDALRPLTS
                     SVAGFLNLSGKGEILPGNDADLLVMTPELRIEQVYARGKLMVKDGKACVKGTFETA"
     gene            10488..11399
                     /gene="hypT"
                     /locus_tag="IT892_003412"
                     /gene_synonym="qseD"
     CDS             10488..11399
                     /gene="hypT"
                     /locus_tag="IT892_003412"
                     /gene_synonym="qseD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypochlorite stress DNA-binding transcriptional
                     regulator HypT"
                     /protein_id="HAP3136595.1"
                     /translation="MDDCGAVLHNIETKWLYDFLTLEKCRNFSQAAVSRNVSQPAFSR
                     RIRALEQAIGVELFNRQVTPLQLSEQGKIFHSQIRHLLQQLESNLAELRGGSDYAQRK
                     IKIAAAHSLSLGLLPSIISQMPPLFTWAIEAIDVDEAVDKLREGQSDCIFSFHDEDLL
                     EAPFDHIRLFESQLFPVCASDEHGEALFNLAQPHFPLLNYSRNSYMGRLINRTLTRHS
                     ELSFSTFFVSSMSELLKQVALDGCGIAWLPEYAIQQEIRSGQLVVLNRDELVIPIQAY
                     AYRMNTRMNPVAERFWRELRELEIVLS"
     gene            complement(11392..11784)
                     /gene="iraD"
                     /locus_tag="IT892_003413"
     CDS             complement(11392..11784)
                     /gene="iraD"
                     /locus_tag="IT892_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418746.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraD"
                     /protein_id="HAP3136596.1"
                     /translation="MMRQSLQAVLPEISGNKTSPLRKSVCSDLLTLFNSPHSALPSLL
                     VSGMPEWQVHNPSDKHLQSWYCRQLRSSLLFHEPRIAALQVNLKEAYCHTLAISLEIM
                     LYHDDESLTFDLVWDNGGWRSATLENVS"
     gene            complement(11781..11864)
                     /locus_tag="IT892_003414"
     CDS             complement(11781..11864)
                     /locus_tag="IT892_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iraD leader peptide"
                     /protein_id="HAP3136597.1"
                     /translation="MENEHQYSGARCSGQAAYVAKRQECAK"
     gene            12738..13242
                     /locus_tag="IT892_003415"
                     /pseudo
     CDS             12738..13242
                     /locus_tag="IT892_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966901.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2686 family protein"
     gene            complement(13383..14156)
                     /gene="uxuR"
                     /locus_tag="IT892_003416"
     CDS             complement(13383..14156)
                     /gene="uxuR"
                     /locus_tag="IT892_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Uxu operon transcriptional regulator"
                     /protein_id="HAP3136598.1"
                     /translation="MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLD
                     VTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSHNTDSPDANVCNDAGPFELLQAR
                     QLLESNIAEFAALQATREDIVKMRQALQLEERELASSAPGSSESGDMQFHLAIAEATH
                     NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKL
                     AMWQHLENVKQRLLEFSNVDDIYFDGYLFDSWPLDKVDA"
     gene            complement(14371..15831)
                     /locus_tag="IT892_003417"
     CDS             complement(14371..15831)
                     /locus_tag="IT892_003417"
                     /EC_number="1.1.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HAP3136599.1"
                     /translation="MTTIVDSNLPVARPSWVHSRLESRIVHLGCGAFHRAHQALYTHH
                     LLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALH
                     PEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS
                     AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENV
                     TFPCTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKV
                     GAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTNPDYRKAAFALMMQE
                     QAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQN
                     GGSWRHLALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLS
                     GIFADDLPQNADFVGAVTAAYQQLCERGARECVAAL"
     gene            complement(15912..17096)
                     /gene="uxuA"
                     /locus_tag="IT892_003418"
     CDS             complement(15912..17096)
                     /gene="uxuA"
                     /locus_tag="IT892_003418"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709912.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP3136600.1"
                     /translation="MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEE
                     ILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCY
                     NFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAV
                     RFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKA
                     IIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYG
                     VRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEE
                     HRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFF
                     SR"
     gene            17436..18779
                     /gene="gntP"
                     /locus_tag="IT892_003419"
     CDS             17436..18779
                     /gene="gntP"
                     /locus_tag="IT892_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate permease GntP"
                     /protein_id="HAP3136601.1"
                     /translation="MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGM
                     DLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQL
                     SVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQ
                     PGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVD
                     MNNLPSFGVSILVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVA
                     FVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSH
                     GNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLAT
                     AAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA"
     gene            complement(18953..19123)
                     /locus_tag="IT892_003420"
                     /pseudo
     CDS             complement(18953..19123)
                     /locus_tag="IT892_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313306.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
BASE COUNT         4430 a         4856 c         4879 g         4996 t
ORIGIN      
        1 aattttaatt acacttaagg tgtatatttt ctatgcaagc catcaattaa agaggtgtaa
       61 tgtgctgatg actatttgta atcgttatac attctgacct ggagtcagaa ggtatttctc
      121 tgtctgtgta ttcgcaggca gtgtggttga ttacatgaaa ttcagtacat ttgtccttct
      181 cgcctgcctt tcgtcattac cgacggtatt gaatttcgtt ttccccattg gggttctccg
      241 gacaaggagt tgtttgttat gccacgtttt tttgcccgcc atgccgccac gctgtttttc
      301 ccgatggcgt tgattttgta tgactttgct gcgtatctgt cgacggacct gatccagcca
      361 gggatcatta atgtggtccg tgattttaat gccgatgtca gtctggcccc ggctgccgtc
      421 agtctctatc tcgctggagg catggcattg cagtggctgc tggggccgct ttccgacagg
      481 gttggccgca ggccggtgct gattaccggg gcgctaatat ttacccttgc ctgcgctgcg
      541 acaatgttca caacgtctat gacacagttt cttatcgcgc gtgcaattca gggcaccagt
      601 atctgtttta ttgccaccgt tggttatgtc acggtgcagg aggcgttcgg acagacaaaa
      661 gggatcaagt tgatggcgat tatcacctcc atcgtactga ttgcgccgat tattggcccg
      721 ctttccggcg cagctctgat gcactttgtg cactggaaag tcctttttgc catcattgcg
      781 gttatgggtt ttatctcatt tgttggctta ctgctggcga tgccagagac ggtgaagcgc
      841 ggcgcggttc catttagcgc caaaagcgtc ttgcgcgatt ttcgtaatgt cttttgcaat
      901 cggctgttcc tctttggcgc agcaaccatc tctttaagct atatccccat gatgagttgg
      961 gtggctgtct cgccggtgat cctgatcgac gcgggcggct taacaacttc gcagttcgcc
     1021 tggacacagg ttccggtgtt cggcgcggtg attgtcgcga atgccatcgt ggcgcgtttc
     1081 gttaaagatc cgaccgaacc gcgctttatc tggcgtgccg taccccttca actggttggc
     1141 ctcgcgctgt tgattatcgg caatctgctg tcaccgcacg tctggctgtg gtcggtgctg
     1201 ggcaccagtc tgtatgcttt cgggattggt ttgattttcc cgaccttatt ccgctttacg
     1261 ctgttttcca ataacttacc gaaagggacc gtctccgcat cgctgaatat ggtgatcctg
     1321 atggtgatgt ctgtctcggt cgaaatcggc cgctggctgt ggtttaacag cggtcgcttg
     1381 ccgtttcatc tgttagccgt tgtggcaggc gttatcgtcg ttttcaccct ggccggattg
     1441 cttaatcgcg tgctccaaca tcaggctgcc gagctggcgg aggagcggtg atttttgcgc
     1501 gatcctgccg tcaggctcta ttcttaacat tatgaataaa ctcattgaac tcagacgcgc
     1561 caaaatgttg gcgctctctt tactgcttat cgccgctgct acctttgtcg ttacgctgtt
     1621 tttgccgccc aatttttggg tgagcggcgt gaaggcgatt gctgaagcgg cgatggtcgg
     1681 cgcgctggcg gactggtttg cggtggtggc gctgtttcgc cgcgtgccga ttccgatcat
     1741 ttctcgtcat acggcgatta ttccgcgtaa taaagaccgg attggcgaaa atctcggcca
     1801 gttcgtgcag gaaaaatttc tcgataccca atcgctggtg gcattgattc gacgtcacga
     1861 accggcgttg ttgattggca actggtttag tcagccagaa aacgcccgcc gcgttggtca
     1921 gcatctgttg cagatcatga gcggttttct tgaactaacc gatgatgcgc gtattcagcg
     1981 cctgcttaag cgcgcggtcc accgggcgat tgataaagtc gatctttctg gcaccagtgc
     2041 gttgatgctg gagagtatga ctaaaaacga tcgtcatcag gtgctgctgg atacgctgat
     2101 cgcacagttg atcgcccttc tccagcgcga taaatcgcgc aagtttattg cccagcaaat
     2161 tgttcgctgg ctggagagcg agcatccact gaaagccaaa attttgccca ctgaatggct
     2221 gggcgaacat agcgcggagt tggtttctga cgcggtgaat tctttgcttg atgatatcag
     2281 ccgcgatcgt gcgcatcaga tccgccatgc gtttgatcgc gctaccttcg ccctgatcga
     2341 gaaactgaaa aacgatccgg aaatggcggc gcgagccgat gccgtaaaaa gctatctgaa
     2401 agaagatgaa gcttttaacc gctatctcag tgaattgtgg ggggatttac gggaatggct
     2461 gaaagcggat atcaacagtg aagattctcg tgtgaaagaa cgtatcgcgc gggctggtca
     2521 atggtttggc gaaacgttaa ttgccgatga tgccttgcgg gcgtcgttaa atggtcatct
     2581 ggaacaagcc gcacaccgca ttgcgcctga gttttccgca ttcctgactc gccatatcag
     2641 cgacacggta aaaagctggg acgcacggga catgtcgcgg caaatcgagt taaatatcgg
     2701 caaagatctc cagtttatcc gtgtcaacgg tacgctggtt ggcggttgta ttggacttat
     2761 tttgtatttg ctgtcgcagc tcccggcctt gttccccctc ggcaatttat agaaatccat
     2821 gaaaaactaa gtggctaacc gcgagagaga tcaaataaac cactctaaaa gaatggtaat
     2881 aatgtggcct cttttcatta tctcccgtgg tacggggaag gaaaatcatg tcacttgtca
     2941 ccgatctacc cgccattttc gatcagttct ctgaagctcg ccagaaaggc tttctcaccg
     3001 tcatggatct caaggagcgc ggcattccgc tggttggcac ctactgcacc tttatgccgc
     3061 aagagctccc gatggcagcc ggtgcggttg tggtttcgct atgttccacc tctgatgaaa
     3121 ccattgaaga agccgagaaa gatctgccgc gcaacctctg cccgctgatt aaaagcagct
     3181 acggcttcgg caaaaccgat aaatgcccct acttctactt ttctgatctg gtggtcggtg
     3241 aaaccacctg cgacggcaaa aagaaaatgt atgaatacat ggcggagttt aagcccgttc
     3301 atgtgatgca actgccaaac agcgttaagg acgatgcctc gcgtgcatta tggaaagccg
     3361 agatactgcg cttgcaaaaa acggtagaag aacgttttgg gcacgagatt agcgaagatg
     3421 ctctgcgcga tgccattgcg ctgaaaaacc gcgaacgtcg cgcactggca aacttttatc
     3481 atttggggca gttaaatcct ccagcgctta gcggcagcga cattctgaaa gtagtctacg
     3541 gcgcaacctt ccggttcgat aaagaggcgt tgatcaatga actggatgca atgaccgccc
     3601 gcgttcgtca gcagtgggaa gaaggccagc gactggaccc gcacccacgt attttaatca
     3661 ccggctgccc aattggcggc gcagcagaga aagtggtgcg cgcgattgaa gagaatggcg
     3721 gctgggttgt cggttatgaa aactgcaccg gggcgaaagc caccgagcaa tgcgtggcgg
     3781 aaacgggtga tgtgtacgac gcgctggcgg ataaatatct ggcgattggc tgctcctgtg
     3841 tttcgccgaa cgatcagcgc ctgcaaatgc tcagccagat ggttgaagaa tatcaggtcg
     3901 atggcgtagt tgatgtgatt ttgcaggcgt gccataccta cgcggtggaa tcgctggcga
     3961 ttaaacgtca tgtgcgccag cagcacaaca ttccttatat cgctattgaa acagactact
     4021 ccacctcgga tgtcgggcag ctcagcaccc gtgtcgcggc ctttattgag atgctgtaag
     4081 gagtggcagt gacatattcg attggcattg attccggctc aaccgccacc aaagggatct
     4141 tactggctga cggcgtgatt acgcgccgtt tcctcgttcc aacacccttt cgcccggcaa
     4201 cagcaattac tgaagcctgg gaaactctgc gcgaagggtt agagacaacg ccgtttctga
     4261 cgctcaccgg ctacggacgg caactggtgg attttgccga taaacaagtg acggaaatct
     4321 cctgtcacgg gctgggcgca cggtttcttg agccagcaac gcacgcggta atcgacatcg
     4381 gtggtcagga cagcaaagtg attcagcttg atgatgacgg taacctgtgc gatttcctga
     4441 tgaatgacaa atgcgcggca ggcaccgggc gtttcctgga ggtgatctcg cgcacgcttg
     4501 gcaccagcat cgagcaactc gacagcatta ccgaaaatgt cataccgcac gccatcacga
     4561 gtatgtgcac agtgtttgct gaatcagaag tgatcagcct gcgctctgcg ggcgtagcgc
     4621 cagaagcgat tctcgccgga gtgattaacg cgatggcgcg gcggagcgcc aatttcattg
     4681 ctcgtctctc ctgtgaagcg ccgattctgt ttactggtgg cgttagccac tgtcaaaggt
     4741 ttacccacat gctggaaagc catttgggaa tgccggtaca aactcaccct gatgcgcaat
     4801 tcgctggtgc aattggcgcg gcggtgatcg gtcagcggca gagaaaacgc gcatgaaaga
     4861 gtatctgttt ttatttcact ccacggtcgg cgtcatacaa acccgcaagg cgttgcaggc
     4921 agcgggcatg acttttcgcg tcagcgatat tccccgtgat ttacgcggcg gctgcgggtt
     4981 atgcatttgg ctgacctgtc cgcctggcga ggaaattcaa tgggtgattc ctgggcatac
     5041 ggaatcagtt tattgtcagc aggatggtgg ctggcgctgc attgcacatt acgggatttc
     5101 tccgcgttaa ggattcatta agatcgctac gtatacttct cgatatctta ttgatttgcc
     5161 ttaaagggat taccgtgaca aaaagtattt cgttaagtaa acgcatcttc gttattgtga
     5221 ttctttttgt cattgtggca gtgtgtactt tcttcgtgca atcttgcgcc cgtaaaagca
     5281 atcatgcagc atcatttcag aattaccacg ccaccattga cggcaaagaa attgcaggca
     5341 taacgaataa tatctcttcg ctgacctggt cggcacaaag caatactctt tttagcacta
     5401 tcaacaaacc tgccgccatt gttgaaatga ccaccaatgg cgatttgatc cgcacaattc
     5461 ctctggattt tgttaaggat ctcgagacga tcgaatacat tggcgataat cagtttgtca
     5521 ttagcgatga gcgcgattat gccatttatg tgatttcact gaccccaaac tcggaagtaa
     5581 aaatcctcaa aaaaataaaa atcccgctgc aggaatcccc aaccaattgc ggttttgaag
     5641 gattggccta ttctcgccag gatcacactt tctggttttt taaagagaaa aacccgattg
     5701 aggtctacaa agttaacggg ctgttaagta gcaatgaatt gcacatcagc aaagacaagg
     5761 cactacaacg gcaatttact ttagatgatg tgtccggcgc agaatttaac caacaaaaaa
     5821 atacgcttct ggtgctgtct catgaatctc gcgcactcca ggaagtaacg ctggctggcg
     5881 aggttatagg tgaaatgtca ctaaccaaag gcagtcgagg tttgtcgcat aacatcaaac
     5941 aggccgaagg ggttgcgatg gatgcctcag gtaatattta tatcgttagc gaaccaaatc
     6001 gtttttatcg ctttacccct caatcatcgc attaacaggc tggcatgttt cacctttttg
     6061 ttattaactt gttaacaaca aaaatgacaa acaaggttaa acatgccttc gccctcgcat
     6121 cccgtagaac gcttttcttt cagcaccgcg cttttcggga tgctggttct gaccttaggt
     6181 atgggtttag gccgcttcct ttatacgcct atgttgcccg tcatgatggc ggaaggatcg
     6241 ttttcattta gccagctctc gtggattgcc agcggcaact atgcggggta tctggctggc
     6301 agtctgctat tttcgtttgg cgcatttcac cagccatcgc gcctgcgccc atttctgttg
     6361 gcttctgccc tggcgagcgg gttgttgatc ctcgcaatgg catggttgct gccatttatt
     6421 ctggtgttat tgattcgcgt cctggcaggt gtcgccagcg ccggtatgct gatttttggt
     6481 tcgacgctga ttatgcagca cacgcgccat ccttttgtgc tggcagcttt gttttctggc
     6541 gttggcattg gcatcgcact gggcaatgaa tatgttctgg caggcctgca ttttgacctc
     6601 tcctcgcaaa cgttatggca aggcgccggg gcgctttctg gcatgatgct gattgcactt
     6661 acgcttttaa tgccctcgaa aaaacacgcc atcacaccaa tgccattggc aaaaacggag
     6721 caacagataa tgagctggtg gttactggct attctgtacg gcctggcggg atttggttat
     6781 atcatcgtcg cgacttacct gccgctcatg gcgaaagatg caggctcacc attgttaacc
     6841 gcccatctct ggacgttagt cggcttatca attgtgcctg gttgctttgg ctggctatgg
     6901 gcagcaaaac gttggtgggc tttgccctgc ctgacggcga atttgctggt gcaggctatc
     6961 tgtgtgctgc ttactctcgc cagcgactcg cctctcttgc ttatcatcag cagtcttggt
     7021 tttggcggta cctttatggg cacgacatct ctggtgatga ctatcgcccg ccaactgagc
     7081 gtaccgggaa atctcaatct tttaggcttt gtgacgctca tttacggcat tggacaaatc
     7141 ctcggcccgg cgctgaccag tatgctcggc aatggaacat cggcgcttgc cggcgccact
     7201 ctctgcggcg cggcggcgtt gtttattgct gcgcttatca gcacagtaca attatttaag
     7261 ctgcaagtgg tcacttcatg aggagtgttt cccttaccac tcaagaaatt cgaccgcaac
     7321 cgttgatgtc agccagaccc cgttttccgc ttgccagaaa gggaggcctc gtttcgccat
     7381 ttcctgtgct ttgacggtta aaataaccgg cgatccgtgt cttgctccca ctttgcgtgc
     7441 cgttgcttca tcagcagaga gatgtacgta gtgacgctca cctgcaatca gcccctgttt
     7501 ttttatctcg tcaaggaaac ggcttgccgt accgtggtag agaaactgtg gcggtgtttt
     7561 ttcggcaaag gaaatagcga cctgcgaagt cgaatgcccc tgaaccgcgc ggatgcacct
     7621 accatcactg gaataactaa aacgcttttt atcgctggtg gcaaccacgg tatccagcaa
     7681 tgcacgggtt aaccgcttgc ccgctttttg ggcacaaagt atgagcttat cgatatccgc
     7741 ccatccttca cggtccagta cgataccaat cgcctccggt ttgtgtcgga ggacaaaact
     7801 taaaaacttg ctcgtatccg ccagctcttt ttcgttgtac tttgccatcg cgttttcgtc
     7861 cctggattat ctgtttttta tttactatgt cattgtcact gggtttatga attttctgca
     7921 actcaatcct gcgtagaacc ttttccacac agcgtaattt taccgctatg caaaaaacgc
     7981 atagtcagaa acatacttgc attttcccca tacccacatg gctgataagg tttttcagct
     8041 ccaggaattt tcctggctca agcaacacac aaacacaaaa aacaatgggg attgttatga
     8101 cacaacaagg ggatgctgta gccggggagc tggcgacaga aaaagtgggc attaaagggt
     8161 atctggcttt ttttctcacc ataatctttt tttccggtgt tttttccggg acagacagtt
     8221 ggtggcgcgt ttttgatttt tccgttctga acggatcgtt tgggcaactg cctggtgcga
     8281 acggagccac cacctcgttt cgcggcgcgg gtggcgcggg ggctaaagat ggctttctct
     8341 ttgcgctgga gctggcaccg tcagtcattc tctctctggg gattatttca attaccgatg
     8401 gtcttggcgg attacgcgcc gcgcagcagt taatgacgcc agtgctaaaa ccgttgttgg
     8461 gcattccagg gatctgctcg ctggcgctga tcgctaacct gcaaaacacc gatgccgccg
     8521 caggtatgac caaagagctg gcgcaggaag gtgaaattac cgaacgcgat aaagtgattt
     8581 tcgccgcata tcaaaccagc ggtagcgcca ttatcaccaa ctacttctct tccggcgtcg
     8641 cggtgtttgc ctttctgggc acgtccgtaa tcgtaccttt agcagtcatc ctggtgttta
     8701 aatttgtcgg agccaacatt ttgcgcgtct ggcttaactt cgaagaacgt cgcaacccaa
     8761 cgcaaggagc gcaagcatga caactcaggt ccgcaaaaac atcatggata tgtttatcga
     8821 tggtgcgcgc cgtggcttta ctatcgccac gaccaacctg ctgccaaacg tggtgatggc
     8881 gtttgtcatc attcaggcgc tgaaaattac cggcctgctc gactgggtgg ggcatatctg
     8941 tgaacccgta atggcgctgt ggggattacc cggtgaagcg gcaaccgtcc ttttagccgc
     9001 attaatgagt atgggtggcg cagtcggtgt tgccgccagt ctggcaaccg ctggcgcatt
     9061 aaccggtcac gatgtcaccg ttttactgcc cgcgatgtat ttaatgggca acccggtgca
     9121 aaatgtcggt cgctgcctgg ggacagccga agtgaatgcc aaatattacc cgcatatcat
     9181 tacggtctgc gtgattaacg cattgctgtc gatctgggtt atgcagctta ttgtttaaca
     9241 aggagttacc atgattgatt ataccgcagc cggttttacc ctgctgcagg gagcgcattt
     9301 gtatgcgccg gaagatcggg gaatttgcga tgtcctcgtc gctaacggca aaattatcgc
     9361 cgttgccagt aatatccctt ctgacattgt accggactgc acggttgtcg atctcagcgg
     9421 gcagatcctc tgcccaggtt ttattgatca acacgtccat ttgattggcg gtggcggcga
     9481 agcaggtccc acgacgcgca cgcctgaagt ggcgttaagt cgtctgacgg aagcaggcgt
     9541 cacgtcagtg gttggtctgc tgggcaccga ctctatctct cgccacccgg aatccctgct
     9601 cgccaagacc cgtgcgctca atgaagaagg catcagcgcc tggatgctga ccggcgctta
     9661 tcatgtccct tcccgcacta ttacgggttc cgtggaaaaa gacgtggcga ttatcgatcg
     9721 cgtgattggc gtgaaatgcg ccatctctga tcaccgttct gccgcaccgg acgtttatca
     9781 cctggctaat atggtggcgg aatcccgcgt tggcggtttg ctcggcggta aacctggcgt
     9841 caccgtgttc cacatgggcg acagcaaaaa ggcgttacag cctgtctatg acctgctgga
     9901 aaactgcgat gtgccgatta gcaagttgct gccgacccac gttaaccgca acgttccgtt
     9961 gtttgagcag gcgctggagt tcgcgcgcaa aggcggcacc atcgatatca ccagcagcat
    10021 tgacgaacca gtcgcccctg ccgaaggtat tgcccgcgcc gttcaggcgg gtattccgct
    10081 ggcacgcgtc accctcagct ccgacggcaa cggtagccag ccgttcttcg atgacgaagg
    10141 gaatttaacc catatcggtg ttgccggttt tgaaacgttg ctggaaaccg tgcaggtgct
    10201 ggtcaaagat tatgatttca gtatcagcga tgccctgcgc ccgctcacca gtagcgtagc
    10261 cggtttcctt aacctgagcg ggaaaggcga aattctgcca ggcaatgacg cagacttact
    10321 ggtcatgacg ccagaattac gcattgagca ggtatacgct cgcggcaagc tgatggtcaa
    10381 agacggcaaa gcctgcgtga aaggaacgtt tgaaacggca taaacggttg tcagccgccc
    10441 gaatggacgt agaatgcccg caagggcggc tgacagagta aaacgtaatg gatgactgtg
    10501 gtgcggtttt gcataatatt gaaactaaat ggctttatga ttttctgacc ctggaaaaat
    10561 gccgcaattt ttcccaggca gcagtcagtc gcaacgtctc gcaaccggca ttcagccgcc
    10621 gcatccgtgc gctggaacag gcgattggcg ttgaattgtt taaccgccag gtgacgccgc
    10681 tgcaactctc ggaacaaggt aaaatattcc attcgcagat ccgccatctg ttgcaacagt
    10741 tagagagcaa ccttgcagaa ctccgtggtg gcagcgatta cgcgcaacgc aaaattaaaa
    10801 tagccgctgc acactctctt tccctcgggc tgttaccgtc cattatcagc cagatgccgc
    10861 cgctctttac ctgggcaatt gaagctattg atgtcgatga agcggtcgat aaactgcgtg
    10921 aagggcaaag tgactgtatt ttttcctttc acgacgaaga tttgctggaa gcgccgtttg
    10981 accacattcg cttatttgaa tctcaattgt tccccgtttg cgccagtgac gaacacggag
    11041 aagcactttt taacctcgcg cagccacact ttccgttact gaattacagc cgcaactcct
    11101 acatggggcg attgattaat cgcaccctga cgcgccacag tgagttaagt ttcagcacct
    11161 tttttgtctc ttcgatgagc gagcttttaa agcaggttgc cctcgacggc tgtgggattg
    11221 cctggctacc ggaatacgcc atccaacaag aaattcgcag cgggcagctc gttgtactga
    11281 atcgggacga actggtgatc ccgattcagg cctatgcata ccggatgaat acccgcatga
    11341 atccagttgc cgaacgcttc tggcgtgaac tgcgcgagct ggagattgtg cttagctgac
    11401 attctccagc gtcgcactgc gccaaccgcc attatcccag accagatcaa acgttagcga
    11461 ttcatcgtcg tgatacagca ttatctcaag gctgatcgcc agagtgtggc agtacgcttc
    11521 tttcaaatta acctgcaacg ccgcaatccg tggctcatga aataacagtg aagaacgcag
    11581 ctgacggcaa taccagctct ggagatgttt gtcgctcggg ttatgcactt gccactcggg
    11641 catgcctgaa acaagtaatg acggtaatgc cgaatgagga gaattaaaaa gagtgaggag
    11701 atcgctgcat actgatttac gcagcggtga cgttttattg cctgaaattt caggtaaaac
    11761 agcctgaagt gattggcgca tcattttgcg cactcctgac gtttagcaac atatgcggct
    11821 tgccctgaac accgggcacc actgtattga tgctcatttt ccatagccat tcccttttgt
    11881 tcattacatc catgtcagtc tgagacaggc ctgaatcctg tcagcaaagt ataaaacctt
    11941 acttgcctat gaatatctac tgacttttca ggaaaaaagt catgatttga taaaaatcat
    12001 caaactcaaa aaaaaaccgc tagtatattc tgaatattcc gaatagttac gtagatgaaa
    12061 atacttgtca ccaccgctac ttaattccgg tgggaaatta tttatttccg cataatcagc
    12121 tatgtattat ttaaaacaat tagtttgtaa ataatataaa ttgataacat atcaaataca
    12181 tcaaaaatac cattcacagg cattattaat atagacatca atatagcaac atcaaattcc
    12241 aattagtaat aagatatgct tttaaattgc atgcaaataa ttttaaatga gcgttttttg
    12301 atactttaga gtgtttccca ccatttaata tcactgtgta gagttgatat cactacaaca
    12361 aaaacatgca tgtcatttgt ttacttctct ttttaccaca gaaaaattta tctatttttc
    12421 taagcatcag tgaaatactc ataaaggtaa ctattatgtc tatgccatta agcaatgccc
    12481 ttcagagtta aattattaca tataatcact tccttcatca tccaaaagtc gacagtgagt
    12541 taacacgtaa acatgaacgt gcacgcatgg atacggaaaa tatctatctt ccgcctcttg
    12601 ctcgtggcaa taaccataat tacgatggaa aaagcgttgt cgaaattaga aaacttgata
    12661 ttagtaaaga gtcctggcca tttaattatg tgacagaaac atgcagagaa ttcaatggta
    12721 ttacaacaac aggacgtatg ctctatcgaa acttgaaaat cacctcagct ttagacgaaa
    12781 tatatggtgg tatatgtaaa aaggcgcatg ctgccacaga gttagcaaaa ggattacggc
    12841 taaatttatt tatgaaaggc cctttcgatc ctgttgagga ctatacagtt catgaaataa
    12901 cattagaccc tggttgcaat gttcctggtt atgccggaac cacgatagga tatatttcaa
    12961 cccttccagc ttctcaggca aaaagatgga ccaatgagca gccaaggatt gatatctata
    13021 ttgatcagat aatgacggta acaggggtag caaattcttc cggattcgcc cttgccgcat
    13081 tacttaatgc taatattgag ttgggtaatg acccaataat tggtatagaa gcctatcccg
    13141 ggtgatgaaa atgcaccact caaacgtatg actctgcaac cgtcatctct tccagaactg
    13201 tttgaattaa aaaatggtga atggaattat attggtaaat aactaccagg aagaatgagt
    13261 actaacattc aggttataca gatagctaaa caatcccctg caatttacaa agtaatactc
    13321 attgcgactt cttaatttaa gaaagcgcaa ggaacgttta cccttgcgct tattataata
    13381 agtcaggcgt cgactttatc cagcggccat gaatcaaaca gatagccatc aaaataaata
    13441 tcgtcaacgt tcgagaattc cagcagacgt tgcttaacgt tttccagatg ctgccacatt
    13501 gccagcttcg ccgctcgggc atcttttttg attaacgcgg cgaggatctg tttgtgatcg
    13561 cccaaccact ctttgcgata caggctgtca tccagatggc tgtgcaactg gatccacatt
    13621 ggattgtttt cccgccactg ccaggactga cggaacagct ccaccagcat gctgttatgc
    13681 gttgcttcgg caatagcgag atggaactgc atgtcaccgc tttcgctgct gcccggcgca
    13741 ctggaagcca gttcacgctc ttccagttgc aatgcctgac gcattttgac gatatcttcg
    13801 cgggtagcct gcagggcggc aaactcggcg atgttgctct caagaagctg tcgcgcctgc
    13861 aacagctcaa aaggacccgc atcattgcaa acgttggcat ccggactgtc tgtgttgtgg
    13921 ctgcctgagc tatcaagaac atagataccg gcaccccggc gcacttccac cagccctttg
    13981 atctccagca tgatcagcgc ttcacgtacc accgtccgcg tgacatcaag catttctgca
    14041 atttcacgct ccggcggcaa ccgttcgcca ggattgtacg gcgtctttat gatcagatcg
    14101 cggatcatcg ccccgacttc ctggtaaggt ctttgcgcag aggtggcaga tttcatggtg
    14161 ttgtgtccgt taggtgcggt taatcaaatt tttgccggat gcggcgtgaa cgccttatcc
    14221 ggcctacaac gggcaatttt acggcacccg ttaatctcaa actataccat tagcactgga
    14281 agttggcacg tacaggtggg caaaaaaacg aaaactggtc aaccaaatat cagtttgatt
    14341 gaccagtaag tctgtagggt aatcagttag ttacagcgca gccacacact cgcgcgcacc
    14401 gcgttcgcac agctgctgat atgccgccgt caccgcgcca acaaagtcgg cattctgcgg
    14461 cagatcatcg gcaaaaatac cgctcaggcc cagcagcgct ttcacgcggt ctgcgccctg
    14521 atactgcgcg ttaatcttct ggaactcggc cagcatcggg tcgaccacgt caatggcatt
    14581 accctgctca tccacgccct gggtgtaacg catccagcca gccacgccca gcgccaggtg
    14641 acgccagctg ccgccgtttt gcaggtgcag acgcaccgga tccagcagac gctgcggtaa
    14701 cttctggctg ccgtccatcg caatctgcca ggtacggtga cgcagagacg ggttgctgaa
    14761 acgctcgatc agcagcgtcg cataggcgtt caggtccgta ccttccggca tcgacagcgt
    14821 tggcgcttgt tcctgcatca tcagggcaaa ggccgctttg cgataatccg ggttagtcat
    14881 ggtgtcggca atagtttcat agccgccgag gtaaccgagg tatgccagga aagagtggct
    14941 gccgttcagc atacgcagct tcatcatttc gaacggcaca acgtctgcaa cgaactgtgc
    15001 gcccacttta tcccagtccg gacgaccatt aacgaagtta tcttcaatca cccactgacg
    15061 gaacggttcg caggcaatgg cgcacgggtc ataaacaccc agctggtcag caatttcctg
    15121 taaggtttct ggcgtcgccg ccggaacgat gcggtcaacc atggtgcacg ggaaggtgac
    15181 gttctcttca atccatgccg ccagctgcgg gtcacgcgcc tgagccagcc ccagtaccgc
    15241 gaccttcgcc acatgaccgt tttcacgcac gttatcgcag gacatcaccg taaacgcttt
    15301 cagccctttt tcacgacgca gacgcagggc ttcgacgatg taaccaatcg cagacttcgg
    15361 cgcagtcggg ttttccagat cgtgcttgat cagcgggtta ttgagatcca actgaccgct
    15421 tgccgcatca gcgcagtagc ctttttccgt gaccgtcaga gagacaatcg ccgtctgcgg
    15481 acgcgccatc gcgttgagaa taccttcgca gccgtcgatt tccggatgca gcgcttcttt
    15541 catcgaaccg ataattttca gttcggtgct ttccgcgcct ttttccgcca cggtgtacag
    15601 cagttgctgt tttttcaggt tttcaatcag cacacggtcg ttacctggca tcaggttaac
    15661 ttcgcagata ccccagtcgc tgtcggtgct ttccagcaga tgatgggtat acagcgcctg
    15721 gtgcgcgcgg tgaaacgccc cgcaaccgag atgcacaatg cgtgattcca gacgagaatg
    15781 cacccatgac gggcgggcaa ccggcagatt gctgtcaaca atagtagtca tcgtaaactc
    15841 cagaatccgt cttcagagag tgacggcaag gaagaaggaa ccggcacggc gcgcagccat
    15901 gccggtggat attaacggct aaagaaagcg cgctggatcg ccagttcgac accgcgaact
    15961 tcggccaggc ctttcagacg accaattgcg gagtaacctg ggttagtttt cttcttcagg
    16021 tcgtccagca tctgatgacc gtggtccgga cgcatcggga tcaggtcttc tttgccttcc
    16081 gctttacgac ggtgttcctc ttcaacaatc gctttcacca cttcgtacat atcaacgtca
    16141 ccgttcaggt gcgccgcttc gtggaaggtt ttcgggttat cttcacgcat ggtggagcgc
    16201 agatgggtga agtaaatacg cggaccgaac tgcttgatca tatcaaccag atcgttgtca
    16261 gcacgcacgc cgtaggaacc ggtgcacatg gtgaaaccgt tcgccatgct gtttacggta
    16321 tcaaccatcc actgcatatc ttcaatggtg gaaacaatgc gcggcaggcc gaggatcggg
    16381 cgcggcggat cgtccgggtg aacagccata cggacgccaa cttcttcggc aaccggaata
    16441 atcgctttca ggaagacggc aaagttttcg cgcagtttgg ctttgtcgat atctttatat
    16501 agctccaggt gcttacggaa ctggtcgagg gtgtaccctt cttccgcgcc cggaagacca
    16561 gcaatgatgt tacgggtcag acgcgctttg tcttcgtcgc tcatagtggc gaagcgaaca
    16621 gctgcctgag caatttcttc ttcggtgtaa tccgcttccg cgcctggacg tttcaggata
    16681 tgcatttcga atgcagcgaa ttcgatctgg tcaaagcgca gagctttgga gccgtctggc
    16741 agcacgtatt cgaggtcagt acgggtccag tcgagcaccg gcatgaagtt gtagcacacg
    16801 gtgcgaatgc cgcactgcgc caggttgcgc agagtctgct gatagttagc gatccactgc
    16861 tcatagttgc cagtgtgggt tttgatatct tcgtgaattg gcacgctttc tacgacagac
    16921 cataccaggc ctgcgtcttc aacgatcgcc ttgcgtttga ggatctcttc aacggaccat
    16981 acttcgccgt tcgggatatg gtgcagcgcg gtaaccacgc cagttgcgcc cgcctgacgg
    17041 acatcagcta aagaaaccgg atcgtttggg ccgtaccagc gccaggtctg ttccatgatt
    17101 tttcctcttt cacatagtgg gttccacagc aaagagacgc ggaaccctgg agttgtttag
    17161 gtatccggat gaacaaccag accgcagccg tggcgttgca tcggatgaga tggcgtataa
    17221 gttctacctt ttggtaatac atgtcaaccc gaattctaaa attggttaac cacatcacaa
    17281 gaatttcact ctcctggttg ttgctgcaaa ttgcagcaaa gggtaatcga tggttattga
    17341 tcagaggatg tgacattcat cgcaacaatg gttgaccaat ttacataaca tgtcgcccaa
    17401 aataacaacg gttcaaccag gtaaggtaaa acgttatgca tgtgcttaac attctctggg
    17461 tggtattcgg cattggtctg atgctggtac tgaatttgaa gttcaaaatc aattcaatgg
    17521 tggctttgtt ggtggcggcg ctgtccgtcg ggatgctggc gggcatggat ttgatgtcgc
    17581 tgctgcacac catgaaagcg ggcttcggca acacgctggg ggaactggct atcatcgtgg
    17641 tgttcggtgc ggtcatcggt aaattgatgg tcgactccgg cgcggctcac cagatagcac
    17701 atacgctgct ggcgcgtctc ggtctgcgct atgtacagct gtcggtgatt atcatcggcc
    17761 tgatttttgg tctggcgatg ttctatgaag tggcctttat catgttagcg ccgctggtta
    17821 ttgtcattgc cgccgaagct aaaattccgt tcctgaaact ggcgatcccg gcagtagcag
    17881 ctgccactac cgcacattca ctgttcccac cgcagccggg tcctgtggcg ctggtgaatg
    17941 cttatggcgc agatatgggg atggtttata tctatggcgt actggtgacg atcccaagtg
    18001 taatctgcgc aggtctgatc ctgccgaagt tcctcggcaa tcttgagcgc ccaacgccat
    18061 cattcctgaa agcagatcaa ccggtagata tgaacaatct gccctctttc ggcgtttcga
    18121 ttctggtgcc gctgatcccg gcgatcatta tgatctccac caccatcgcc aatatctggc
    18181 tggtaaaaga tacccctgcc tgggaagtgg ttaactttat cggttcctcg ccgattgcaa
    18241 tgtttattgc gatggtggtt gcattcgtac tctttggcac cgcacgtggt catgacatgc
    18301 agtgggtgat gaacgctttt gaaagtgcgg tgaaaagcat tgcaatggtg attctgatca
    18361 tcggtgcggg tggcgtgttg aagcaaacta tcatcgacac cggcattggc gacaccatcg
    18421 gcatgttgat gtcccacggc aatatctcgc cctacattat ggcatggctg atcactgtgc
    18481 taattcgtct ggcgacgggt cagggtgtcg tttcggcgat gaccgccgcc gggattatca
    18541 gtgctgcaat ccttgatcca gcaaccggtc agctggttgg cgtgaatccg gcgctgctgg
    18601 tgctggcgac ggctgcgggt tccaacaccc tcacccacat taatgatgcc tcattctggc
    18661 tgttcaaagg ttactttgac ctgtcggtaa aagacacgtt gaaaacctgg ggactgctgg
    18721 agctggtcaa ctccgtggtt gggctgatta ttgtgttgat tattagcatg gtagcgtaaa
    18781 agaacaccag agcctgccaa tggcgggctc tgttcggatt gtcggcaaag tgcgctttgt
    18841 ttatgccaga tgcgacgctg acgcgtctta tctggcctac aaagggctaa cgtgcaggtt
    18901 tttagcttca ggtaatattg cgtacctgca ttagcaatgc cctgtgattt ctttattgat
    18961 aaacaaaagt cacgccaata atcgattgca cattccctgc agtcacctgc cctccggtac
    19021 gtgcgtaatt tgccgttaat cccagactta ccgccgaagt ccctactgct cctaacgata
    19081 ccgtgttatt cgctggaata atcgtaccgt tgcgcatcaa ctgggtgatg ctgccaactt
    19141 actgatttag tgtatgatgg t
//
LOCUS       DACAOP010000089        18611 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.089, whole genome shotgun sequence.
ACCESSION   DACAOP010000089 DACAOP010000000
VERSION     DACAOP010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18611
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.089"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            148..573
                     /gene="nudI"
                     /locus_tag="IT892_003421"
     CDS             148..573
                     /gene="nudI"
                     /locus_tag="IT892_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HAP3136602.1"
                     /translation="MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGE
                     RIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSAN
                     REVKINEEFQDYAWVKPEDLAHYDLNVATRKTLRLKGLL"
     gene            complement(612..1214)
                     /locus_tag="IT892_003422"
     CDS             complement(612..1214)
                     /locus_tag="IT892_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP3136603.1"
                     /translation="MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNK
                     TLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFD
                     LYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNH
                     CLTYIAKDKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH"
     gene            1522..2661
                     /gene="arnB"
                     /locus_tag="IT892_003423"
     CDS             1522..2661
                     /gene="arnB"
                     /locus_tag="IT892_003423"
                     /EC_number="2.6.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_024188371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-4-amino-4-deoxy-L-arabinose
                     aminotransferase"
                     /protein_id="HAP3136604.1"
                     /translation="MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQ
                     LTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDV
                     DHDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVG
                     TYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDR
                     QTWGRAPQAEVLTPGYKYNLTDINAAIALTQLAKLEHLNTRRREIALQYQQALAALPF
                     QPLSLPAWPHVHAWHLFIIRVNEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYR
                     ERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ"
     gene            2665..3633
                     /gene="arnC"
                     /locus_tag="IT892_003424"
     CDS             2665..3633
                     /gene="arnC"
                     /locus_tag="IT892_003424"
                     /EC_number="2.4.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate
                     4-deoxy-4-formamido-L-arabinose transferase"
                     /protein_id="HAP3136605.1"
                     /translation="MFEIHPVKKVSVVIPVYNEQESLPELIRRTTKACESLGKEYEIL
                     LIDDGSSDNSAHMLVEASQAENSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDAD
                     LQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
                     CMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHAEREFGESKYSFMRLI
                     NLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAV
                     LFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE"
     gene            3633..5615
                     /gene="arnA"
                     /locus_tag="IT892_003425"
     CDS             3633..5615
                     /gene="arnA"
                     /locus_tag="IT892_003425"
                     /EC_number="1.1.1.305"
                     /EC_number="2.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-4-amino-4-deoxy-L-arabinose
                     formyltransferase/UDP-glucuronic acid oxidase ArnA"
                     /protein_id="HAP3136606.1"
                     /translation="MKTVVFAYHDMGCLGIEALLSAGYEISAIFTHTDNPGEKAFYGS
                     VARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIFSFYYRHLICDEILQLAPAGAFN
                     LHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAIT
                     LHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPEDSFLEWHKPASVLH
                     NMVRAVADPWPGAFSYVGNQKFTVWSSRVHSHAPAAQPGSVISVAPLLIACGDGALEI
                     VTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACAARRRTRVLILGVNGFIGNHLTER
                     LLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAI
                     ATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSN
                     LIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGS
                     SRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIG
                     NPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIR
                     NARRCLDWEPKIDMHETIDETLDFFLRTVDLTDKPS"
     gene            5612..6502
                     /locus_tag="IT892_003426"
     CDS             5612..6502
                     /locus_tag="IT892_003426"
                     /EC_number="3.5.1.n3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-4-formamido-L-arabinose-
                     phosphoundecaprenol deformylase"
                     /protein_id="HAP3136607.1"
                     /translation="MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDN
                     MGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHE
                     VGLHAWDHHAWQAHSGNWDRQTLVDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIE
                     AKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLL
                     NRILRDKGMPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSGTLPLGQVV
                     RGNIAGREGWLGCQQIAGSR"
     gene            6502..8154
                     /gene="arnT"
                     /locus_tag="IT892_003427"
     CDS             6502..8154
                     /gene="arnT"
                     /locus_tag="IT892_003427"
                     /EC_number="2.4.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A)
                     4-amino-4-deoxy-L-arabinosyltransferase"
                     /protein_id="HAP3136608.1"
                     /translation="MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLA
                     SGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFT
                     LRLWRDKRLALLAAVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKG
                     KSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVASQKRWKDLFIYGWLAVISCVLT
                     VLPWGLAIAQREPDFWHYFFWVEHIQRFAMDDAQHRAPFWYYLPVIIAGSLPWLGLLP
                     GALYAGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFAPLAMLMAHYALLA
                     AKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLW
                     AFFGWYTLTNVEKTWSFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSR
                     YILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHR
                     QEGIITLVLSVDRNEDINSLAIPPADAIDRQERLVLIQYRPK"
     gene            8151..8486
                     /gene="arnE"
                     /locus_tag="IT892_003428"
     CDS             8151..8486
                     /gene="arnE"
                     /locus_tag="IT892_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnE"
                     /protein_id="HAP3136609.1"
                     /translation="MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLAL
                     ACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIG
                     GIVILGSTV"
     gene            8486..8872
                     /gene="arnF"
                     /locus_tag="IT892_003429"
     CDS             8486..8872
                     /gene="arnF"
                     /locus_tag="IT892_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416761.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnF"
                     /protein_id="HAP3136610.1"
                     /translation="MGLMWGLFSVIIASAAQLSLGFAASHLPPMTHLWDFIAALLAFG
                     LDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFS
                     LKALLGVACIMSGLMLIFLPTTKQRY"
     gene            complement(8866..9132)
                     /gene="pmrD"
                     /locus_tag="IT892_003430"
     CDS             complement(8866..9132)
                     /gene="pmrD"
                     /locus_tag="IT892_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416762.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein PmrD"
                     /protein_id="HAP3136611.1"
                     /translation="MEWLVKKSCCDKQDNRHVLKLCDAGGTIKMIAEVKSDFAVKVGD
                     LLSPLQNALYCINREKLHTVKVLSASSYSPDEWERQCKVAGKTQ"
     gene            complement(9242..10597)
                     /gene="menE"
                     /locus_tag="IT892_003431"
     CDS             complement(9242..10597)
                     /gene="menE"
                     /locus_tag="IT892_003431"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HAP3136612.1"
                     /translation="MIFSDWPWRHWRQVRGEAIALRLNDEQLNWRELCARVDELASGF
                     AAQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQF
                     ALVPDGENTFPALTSLHIQLVEGAHAAAWQPTRLCSMTLTSGSTGLPKAAVHTYQAHL
                     ASAQGVLSLIPFGEHDDWLLSLPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGC
                     THASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFAS
                     TVCAKEADGLADVGSPLPGREVKIVNDEVWLRAASMAEGYWRNGQLVALVNDEGWYAT
                     RDRGELHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGH
                     RPVAVVEYDQQTVDLSEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQALKEWVQRQ
                     D"
     gene            complement(10594..11556)
                     /gene="menC"
                     /locus_tag="IT892_003432"
     CDS             complement(10594..11556)
                     /gene="menC"
                     /locus_tag="IT892_003432"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HAP3136613.1"
                     /translation="MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGE
                     ISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELTDALPQAA
                     NYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
                     DANRAWTSLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLRE
                     PDFAFVAEEGVSAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLAR
                     IAAWLTPDTIPGLDTLDLMQAQQVRRWPGSPLPLVEVDALERLL"
     gene            complement(11556..12413)
                     /gene="menB"
                     /locus_tag="IT892_003433"
     CDS             complement(11556..12413)
                     /gene="menB"
                     /locus_tag="IT892_003433"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HAP3136614.1"
                     /translation="MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSADGIAKITINRPQV
                     RNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSG
                     VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVG
                     SFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWC
                     REMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQP
                     DFSKFKRNP"
     gene            complement(12428..13186)
                     /gene="menH"
                     /locus_tag="IT892_003434"
     CDS             complement(12428..13186)
                     /gene="menH"
                     /locus_tag="IT892_003434"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HAP3136615.1"
                     /translation="MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEVFANYSRLY
                     VDLPGHGGSAAIRVDGFDDVTGLLRKTLVSYNILNFWLVGYSLGGRVAMMAACQGMPG
                     LCGVIVEGGHPGLQNAEQRTERQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDEQ
                     RRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAA
                     ELAAECHVIPRAGHNAHRENPAGVIASLAQILRF"
     gene            complement(13183..14853)
                     /gene="menD"
                     /locus_tag="IT892_003435"
     CDS             complement(13183..14853)
                     /gene="menD"
                     /locus_tag="IT892_003435"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HAP3136616.1"
                     /translation="MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAEN
                     SAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLIL
                     LTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLH
                     AGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWR
                     QKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSEL
                     QQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWL
                     EQHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRISDYLPEQGQLFVGNSL
                     VVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLN
                     ALALLRQVSAPLVLIVVNNNGGQIFSLLPTPKNERERFYLMPQNVHFEHAAAMFELKY
                     HCPQNWQELETALADAWRTPTTTVIEMVVNDTNGAQTLQQLLAQVSHL"
     gene            complement(14942..16237)
                     /gene="menF"
                     /locus_tag="IT892_003436"
     CDS             complement(14942..16237)
                     /gene="menF"
                     /locus_tag="IT892_003436"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HAP3136617.1"
                     /translation="MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWL
                     ASQQTYPQFYWQQRNGDEEAAVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDP
                     SQGNLLLPRLEWRRCGGKATLRVTLFSESSLQHDAIKAKEFIAKLVSIKPLPGLHLTT
                     TREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLN
                     LNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANHPDDKQAQQLGEWLM
                     ADDKNQRENMLVVEDICQRLQADTLTLDVLPPQVLRLRKVQHLRRCIWTALNKADDVI
                     CLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKIS
                     GNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQME"
     gene            complement(16316..16621)
                     /gene="elaB"
                     /locus_tag="IT892_003437"
     CDS             complement(16316..16621)
                     /gene="elaB"
                     /locus_tag="IT892_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein ElaB"
                     /protein_id="HAP3136618.1"
                     /translation="MSNQFGDTRIDDDLTLLSETLEEVLRSSGDPADQKYVELKARAE
                     KALDDVKKRVSQASDSYYYRAKQAVYRADDYVHEKPWQGIGVGAAVGLVLGLLLARR"
     gene            complement(16676..17137)
                     /locus_tag="IT892_003438"
     CDS             complement(16676..17137)
                     /locus_tag="IT892_003438"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP3136619.1"
                     /translation="MIEWQDLHHSELSVSQLYALLQLRCAVFVVEQNCPYQDIDGDDL
                     TGDNRHILGWKNDELVAYARILKSDDDLEPVVIGRVIVSEALRGEKVGQQLMNKTLET
                     CTRHWPDKPVYLGAQAHLQNFYQSFGFIPVTEVYEEDGIPHIGMAREVIQA"
     gene            17202..18119
                     /gene="rbn"
                     /locus_tag="IT892_003439"
     CDS             17202..18119
                     /gene="rbn"
                     /locus_tag="IT892_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416771.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="HAP3136620.1"
                     /translation="MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQ
                     HQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPQGIREFVE
                     TALRISGSWTDYPLEIVEIGAGEILDDGLRKVTAYPMEHPLECYGYRIEEHDKPGALN
                     AQALKAAGVPPGPLFQALKAGKTITLEDGRQINGADYLAAPVPGKALAIFGDTGPCDA
                     ALDLAKGVDVMVHEATLDITMEAKANSRGHSSTRQAATLAREAGVGKLIITHVSSRYD
                     DKGCQHLLRECRSIFPATELANDFTVFNV"
     gene            18307..>18611
                     /locus_tag="IT892_003440"
     CDS             18307..>18611
                     /locus_tag="IT892_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416772.1"
                     /note="ElaD; specific cysteine protease which targets
                     ubiquitin and ubiquitin-like proteins covalently bound to
                     target proteins; SseL in Salmonella is required for
                     macrophage killing and virulence, and it is secreted by
                     the salmonella pathogenicity island 2 type III secretion
                     system; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deubiquitinase"
                     /protein_id="HAP3136621.1"
                     /translation="MMVTVVSNYCQLSQTQLCQTFAEKFTVTEELLQSLKKTALSGDE
                     ESIELLHNIALGYDEFGKKAEDILYHIVRNPTNETLSIIRLIKNACLKLYNLAHTATT
                     "
BASE COUNT         4455 a         4954 c         4655 g         4547 t
ORIGIN      
        1 aacgccgaaa aaataaacat actttatcga tacacacaaa aataataata agtgccgtta
       61 tcatcgcaaa agagattact gtcactttca catatttctg agttaccgta ttctcatggt
      121 ttctttttat ttataaggaa tacccctgtg cgacaacgga ctattgtatg ccctttgatt
      181 caaaatgatg gtgcttattt gctgtgtaaa atggccgacg atcgcggcgt tttccccggt
      241 caatgggcgc tttcgggtgg cggcgtagag cctggcgaac gaattgaaga ggcactacgc
      301 cgcgaaattc gcgaagaact gggagaacag ctgcttttga cagaaatcac gccgtggacc
      361 ttcagcgatg atattcgcac caagacgtat gcagatggtc gcaaggaaga gatttatatg
      421 atttacctga tttttgactg cgtttctgcc aaccgagaag tgaaaataaa cgaagagttt
      481 caggactacg cgtgggtaaa acctgaagat ctggcgcact atgatttgaa tgtcgccacc
      541 cgaaaaacgt tacgtttgaa aggtcttctg taacaatgat gacagccatt actggctgtc
      601 agattgaaaa tttagtggtt aacgaattcc ccatccagat aaactttgcc tttttccaca
      661 tgcatgacta aaccatccag ataatcaggt ttaaatgtcg catcacgctt atctttagca
      721 atatatgtca ggcaatgatt atgggtgaaa ataacgatat ttttatcagg cgctttgctt
      781 tgtaagtcct taattgcact ataaatctca ttaccgcact gaagaagtcg tttatctacc
      841 gtcagctttt tacccgctga aaaccaggtc gccgactgaa tggtccggac ggtattactg
      901 gaataaagat cgaaatcagg gatatcagca ctaaaagcgt tgcccagttc acgggcatcc
      961 tgggtacctt taaccgtaat acctgtttta tctgacaagc attggttggt tgaacgatcg
     1021 caacgttcag catggcgaaa caaaacgaca accggatgct gctgtgccag tctggccagc
     1081 gttttattgt cgatacgtgg caaaccattg ctactccagg cggcatgagt acccagtccg
     1141 gcaattgcag cgagcgccag taaaatgatg aaatattttt ttgacttcaa cgaagagcgg
     1201 caaaaagcta acacgtaaac tccacctata gacaagcgca accagacaat taccgtgaaa
     1261 ttgagcgaca tttctggcga taattagcag ttggtgtaat attaaaaatc ctgcgatgcc
     1321 ggcaaaatgc ctcaaaattt tgccaaatgc aaagcctaaa taagaaaaaa tataaaaatt
     1381 tcaatattta cgtctaatat tagtttctta aggttaagtt aatattctat ccttaaaatt
     1441 ttgctccaaa tggcaaaata tacacaacac tctttatagc aaatataagt ggacaggtat
     1501 tcaatggcgg aaggaaaagc aatgtcagaa tttttgcctt tttcgcgacc agcaatgggc
     1561 gtggaggaac tcgctgcagt taaagaggtt ctcgaatccg gttggatcac aaccggtccg
     1621 aagaatcagg cgcttgaaca agccttttgc cagttgacgg gaaatcagca tgccatcgcg
     1681 gtcagttcag ccaccgccgg aatgcatatc acgctaatgg cgttggaaat tggcaagggc
     1741 gatgaagtga ttacgccttc cctgacctgg gtttcaaccc tcaatatgat ttccttgttg
     1801 ggtgcaacgc cggtaatggt ggatgtcgac cacgatacgc tgatggtcac gcctgaagcg
     1861 atcgagtcag ccattacgcc acgcactaaa gccatcattc cggtgcatta tgccggtgcg
     1921 ccagcagata ttgacgccat tcgcgccatt ggcgaacgtt acggcatcgc agttatcgaa
     1981 gatgctgccc atgccgtcgg tacgtattac aaaggccgac atattggcgc aaaaggtacc
     2041 gctatttttt cttttcacgc catcaaaaat attacctgtg cggaaggtgg cctgattgtt
     2101 acagataatg aaaaccttgc ccgccagcta cggatgctaa aatttcacgg tctgggtgtc
     2161 gatgcctatg acagacaaac ctggggccgt gcaccgcaag ctgaagtctt aacgccgggc
     2221 tataagtata atctgaccga tattaacgcc gcgattgccc tgacccagtt agccaaatta
     2281 gagcacctca acacccgtcg gcgcgaaatt gctctgcaat atcagcaagc actggcagct
     2341 ctcccctttc agccattaag ccttcccgcc tggccgcacg ttcacgcctg gcatctgttt
     2401 attattcgtg tcaatgaaca acgttgtggt atcagtcgcg atgcgttgat ggaagcgtta
     2461 aaagaaagag gcattggtac cgggttacat ttccgcgccg ctcacacaca aaaatattat
     2521 cgcgagcgtt ttcccacgct gtcgttaccg aataccgaat ggaatagcga acgcatctgt
     2581 tcgttgccgc tgttcccgga tatgaccacc gccgatgccg accgcgtcat cacagccctt
     2641 cagcaactcg caggacaata agccatgttt gaaatccacc ctgttaagaa agtctcggtg
     2701 gttattcccg tttataacga gcaggaaagc ttaccggaat taatcaggcg caccacaaaa
     2761 gcctgtgaat cactggggaa agagtatgag atcctgctga ttgatgacgg cagtagcgat
     2821 aattccgcac atatgctggt cgaagcctca caagcggaga acagccatat tgtgtctatt
     2881 ttgcttaacc gcaattacgg gcaacattca gcgattatgg cgggattcag tcacgttact
     2941 ggcgacttaa ttattaccct tgatgccgat ctccagaatc cgccagagga gatcccccgc
     3001 ctggtggcaa aagccgatga aggctacgac gtggtaggaa ctgtgcgtca gaaccgccag
     3061 gacagctggt ttcgtaaaac ggcatcgaag atgattaacc ggcttattca gcgcaccacc
     3121 ggcaaagcga tgggtgacta cggttgtatg ctgcgcgcct atcgccgtca tattgtcgat
     3181 gcgatgttgc actgccatga acgcagcacc tttatcccga ttctggcgaa tatcttcgcc
     3241 cgccgtgcca ttgaaattcc agtgcaccat gccgagcgtg agtttggtga atccaaatac
     3301 agttttatgc gcctgattaa tttgatgtac gacctggtga cctgccttac cacaacgccg
     3361 ctacgtatgc tgagtctgct tggcagcatt attgcgattg gaggttttag cattgcggtg
     3421 ctgctggtga ttttacgcct gaccttcgga ccacaatggg cggcagaagg cgtctttatg
     3481 ctatttgccg tgctgtttac ttttattggc gctcagttta tcggcatggg attgctcggt
     3541 gaatatatcg gcaggatcta caccgatgtc cgcgcccgcc cccgctattt tgttcagcaa
     3601 gttatccgtc catccagcaa ggaaaatgaa taatgaaaac cgtcgttttt gcctaccacg
     3661 atatgggatg cctcggtatt gaagccctgc tgtctgccgg ttacgaaatt agcgccattt
     3721 ttacccatac cgataatccc ggtgaaaaag ccttttatgg ttcggtggct cgtctggcgg
     3781 cggaaagagg cattccggtt tatgcgccgg ataacgttaa tcatccgctg tgggtggaac
     3841 gtattgccca actctcacca gaggtgattt tctcttttta ttatcgccat cttatttgcg
     3901 acgagatttt gcagctcgct cccgcaggtg catttaatct gcatggttcg ctgttaccaa
     3961 aatatcgtgg tcgcgcgccg ctgaactggg tgctggtgaa cggtgaaacg gaaactggcg
     4021 ttacattgca ccgaatggtg aaacgtgccg atgccggggc cattgtggcg caactgcgca
     4081 ttgccattgc gccagacgat atcgctatta cgctgcatca taaattgtgc catgccgcgc
     4141 gccagctact ggaacagaca ttacccgcca ttaaacacgg taatattctg gaaatcgccc
     4201 agcgcgaaaa cgaagccacc tgttttggtc gcagaacacc ggaagacagt ttcctcgaat
     4261 ggcataaacc ggcatccgtg ctgcacaaca tggtgcgtgc cgttgccgat ccgtggccgg
     4321 gtgccttcag ctatgttggt aatcagaaat ttaccgtctg gtcgtcacgc gtgcattctc
     4381 atgcgcccgc agcacaaccg gggagcgtga tttctgttgc gccactgctg attgcctgtg
     4441 gcgatggcgc gctggaaatc gtcaccggac aggcgggcga cggcattact atgcagggct
     4501 cgcaattagc gcagacgctg ggcctggtgc aaggttcacg cttgaatagc cagcctgcct
     4561 gtgccgcccg acgccgtacc cgggtactca tcctcggggt gaatggcttt attggcaacc
     4621 atctgacaga acgcctgctg cgcgaagatc attatgaagt ttacggtctg gatatcggca
     4681 gcgatgcgat aagccgtttt ctgaatcatc cgcattttca ctttgtcgaa ggcgatatca
     4741 gtattcattc cgaatggatt gagtatcacg tcaaaaaatg tgatgtcgtc ttgccgctgg
     4801 tggcgatagc cacgccgatt gaatataccc gcaacccact gcgcgtattt gaactcgatt
     4861 ttgaagagaa tctgcgcatt atccgctact gcgtgaagta ccgtaagcga atcatcttcc
     4921 cgtcgacttc agaagtttat gggatgtgta gcgataaata cttcgatgag gatcattcta
     4981 atttaatcgt cggcccggtg aataaaccac gctggattta ttcggtgtct aaacaattac
     5041 ttgatcgggt tatctgggcc tatggcgaaa aagagggttt acagtttacc ctcttccgcc
     5101 cgtttaactg gatgggacca cgactggata accttaatgc ggcacgaatc ggcagctccc
     5161 gcgctattac gcaactcatt ctcaatctgg tagaaggttc accaattaag ctaattgatg
     5221 gcggaaaaca aaaacgctgc tttactgata tccgggatgg tatcgaggcg ttgtaccgca
     5281 ttatcgaaaa tgcgggaaat cgctgcgacg gcgaaattat caacattggc aatcctgaga
     5341 acgaagcgag cattgaggaa ctgggcgaga tgctgctggc gagcttcgaa aaacatccgc
     5401 tgcgccatca cttcccaccg tttgcgggct ttcgtgttgt cgaaagtagc agctactacg
     5461 gcaaaggata tcaggacgta gagcatcgta aaccgagcat ccgcaatgcc cgccgctgcc
     5521 ttgactggga acccaaaatt gatatgcatg aaaccatcga cgaaacgcta gatttcttcc
     5581 tgcgcaccgt tgatcttacg gataaaccat catgaccaaa gtcggcttac gcattgatgt
     5641 cgataccttt cgtggcaccc gtgaaggcgt gccgcgtctg ctggaaatct tgagtaagca
     5701 taatattcag gccagcattt ttttcagcgt cggcccggac aatatgggcc gccatctctg
     5761 gcgactggtg aagccacagt ttttgtggaa gatgctgcgc tcaaacgcgg catcgcttta
     5821 tggctgggat attttactgg caggtacggc ctggccgggt aaagagattg gtcatgccaa
     5881 tgccgatatc attcgtgaag cagctaaaca tcacgaagtc ggcctgcacg cctgggatca
     5941 ccatgcctgg caagcccata gcggtaactg ggatcggcaa acattggtcg acgatattgc
     6001 acgcggcctt cgcaccctgg aagagatcat aggtcaaccg gtaacctgtt ctgccgctgc
     6061 gggctggcgt gccgaccagc aggtgatcga agcaaaagaa gcgttccatt tgcgctacaa
     6121 cagcgattgt cgtggggcca tgccgtttcg gccactgctc gaatcaggaa accctggcac
     6181 tgcgcaaatt ccggtgacct tacccacctg ggatgaagtg attggtcggg atgtgaaagc
     6241 agaagatttt aacggttggt tactcaaccg catcctgcga gataaaggca tgccggttta
     6301 taccattcat gcagaagttg aaggctgcgc ttatcagcat aattttgtgg atctcctgaa
     6361 acgggcagcc caggaaggcg tgacattttg ccctttaagc gaactgttat cagggacgtt
     6421 gccgctcgga caagttgttc gcggaaatat tgccggacgt gaaggctggc tgggttgcca
     6481 acaaattgcg ggtagtcgtt gatgaaatcg gtacgttacc ttatcggcct cttcgcgttt
     6541 attgcctgct attacctgtt accgatcagc acgcgtctgc tatggcaacc cgatgaaacg
     6601 cgttatgcgg aaatcagtcg ggaaatgctg gcatccggcg actggattgt gccccatctg
     6661 ttagggctac gttatttcga aaaacccatt gccggatact ggattaacag cattgggcaa
     6721 tggctatttg gcgcgaataa ctttggtgtg cgggcaggcg ttatctttgc gaccctgtta
     6781 actgccgcgc tggtgacctg gtttactctg cgcttatggc gcgataaacg tctggctcta
     6841 ctcgccgcag tgatttatct ctcattgttt attgtctatg ccattggcac ttatgccgtg
     6901 ctcgatccgt ttattgcatt ctggctggta gcgggaatgt gcagcttctg gctggcaatg
     6961 caggcacaga cgtggaaagg caaaagcgcg ggatttttac tgctgggaat cacttgcggc
     7021 atgggggtga tgaccaaagg ttttctcgcc cttgccgtgc cggtattaag cgtgcttcca
     7081 tgggttgcat cgcaaaaacg ctggaaagat ctctttattt acggctggct ggcggttatc
     7141 agttgcgtac tgacggttct cccctgggga ctggcgatag cgcagcggga gcctgacttc
     7201 tggcactatt ttttctgggt tgagcatatt caacgctttg caatggatga tgctcagcat
     7261 agagctccgt tctggtacta cttgccggtc atcattgccg gtagcctgcc gtggctggga
     7321 ttactccccg gagcactgta cgcaggctgg aaaaaccgca agcattccgc aaccgtctat
     7381 ttgttgagct ggacgataat gccgctgctg tttttctccg tcgctaaagg caaattgccc
     7441 acctatattc tttcctgctt tgcacctctg gcaatgctga tggcgcatta cgctttgctg
     7501 gcagcaaaaa ataatcctct ggcgctgcgg attaatggct ggattaacat cgcttttggt
     7561 gtcactggca ttattgccac atttgtggtc tccccatggg gaccaatgaa cacgccagtg
     7621 tggcaaacct tcgagagcta taaagtcttt tgtgcctggt cgattttttc gctatgggca
     7681 tttttcggct ggtacacctt aacaaacgtc gaaaagacct ggtcttttgc cgcgctttgc
     7741 ccgctggggc tggcgttgct ggtaggattt tcaattcctg acagagtcat ggaaggaaaa
     7801 catccgcaat tttttgtcga gatgacacaa gaatcacttc agccaagccg ctatattctt
     7861 actgatagcg tcggcgttgc cgcaggtctg gcatggagcc tgcaacgcga tgacatcatc
     7921 atgtatcgcc agacaggtga gttgaaatac ggccttaatt atccggatgc gaaagggaga
     7981 tttgtcagcg gtgatgagtt cgcaaactgg cttaatcaac atcgtcagga ggggattatt
     8041 acactcgtgc tttcggttga ccgcaatgaa gatatcaaca gtctcgccat tccgcccgca
     8101 gatgccatcg atcgtcagga gcgtctggtg ctgattcagt atcgtcccaa atgatctggc
     8161 taacattagt ctttgccagc ttgcttagcg ttgccgggca gttgtgtcag aaacaggcaa
     8221 cctgctttgt ggcgataaac aaacggcgca aacatatcgt gctgtggctg ggactggcgc
     8281 tggcttgtct tggtcttgcc atggtgctct ggctgctggt cttgcagaac gtaccggtag
     8341 gcattgccta cccgatgtta agtctgaatt ttgtctgggt gacgctggct gcagtaaaac
     8401 tgtggcacga accggtatcg ccgcgtcact ggtgtggggt ggcgttcatt attggtggca
     8461 ttgtgatcct cgggagtacc gtgtaatggg cctgatgtgg ggattattca gcgtcattat
     8521 cgcctccgct gcgcaattaa gcctgggttt tgcggcgagt catctgccgc cgatgacgca
     8581 cttatgggat tttatcgcgg cgctgttagc ttttggcctg gatgcccgga tactgttact
     8641 cgggctgctg ggttatctgc tttccgtttt ttgttggtat aaaacactac ataaacttgc
     8701 actaagcaaa gcctatgcct tgctcagtat gagttatgtg ctggtatgga ttgcttcaat
     8761 ggtacttccc ggctgggaag ggactttttc gctgaaagca ctactgggag tagcctgtat
     8821 tatgagcggg ttgatgctga ttttcctgcc cacgacaaaa caacgttact gagttttccc
     8881 tgccacttta cactgccgtt cccactcatc ggggctataa ctgcttgccg agaggacttt
     8941 caccgtatgc agcttttcac gattaataca ataaagcgca ttctgcaaag gcgagagtaa
     9001 atcccccact ttcacggcga agtcactctt cacttcggcg atcattttta tcgtgccacc
     9061 agcatcacaa agcttaagta catgtctgtt atcttgttta tcacagcatg actttttaac
     9121 cagccattcc attgcaccac cctgcttgat aagaattttc acattaattt acagattaac
     9181 agataaacct attatcaacg gcaatggaat ggcaaaattg cgaagtgaaa ctaatgattt
     9241 cttaatcctg gcgttgcacc cactctttta gcgcctgacg tgaaatctta atgccgccgt
     9301 ttttcagttc aggcggcagc gttaaccaac gcaccggttg ctgaaaacgg gccagcttat
     9361 ctttcaccca ttcactaaga tcaacggttt gctggtcata ctccaccacc gctaccggcc
     9421 gatgaccaaa ctccttgtcg gcaacgggga cgataaacac ctgcaaaacc gcaggatgtg
     9481 cagcaataac gcgctcgact tcttccggct gaataccctc accgccactg aagaacagat
     9541 tgtctaaacg cccgacaatg gtcagcttgc cattatgcag ctcaccgcgg tcgcgcgtag
     9601 cgtaccagcc ttcgtcatta accagtgcca ccagttgccc gttacgccag taaccttcag
     9661 ccatactggc agcccgcagc cacacttcat cattaacgat tttcacttcc cgacccggca
     9721 gcggcgaacc aacgtctgcc agaccgtcgg cttctttcgc acacaccgtg gaggcaaact
     9781 cggtcagacc atagccgcaa aagcaacgaa tcccctgctc gcgcgcctgt tccgtcaact
     9841 cgaccgggat agccgcgccg ccaagtagca ccgctttcag ggaaacggaa ctacggttaa
     9901 ccagcaaacg ccagagttgt gttggcacca gtgaagcgtg agtacagcct gccagcattt
     9961 gctccaatgg ctgtttatca cgtaccgtca tccgcgcacc agcgtataac cagcgccaca
    10021 taattccctg accggagacg tgaaacagcg gtaaagagag caaccagtca tcgtgctcgc
    10081 caaacggtat cagcgataac acaccttgcg cactggcaag atgggcctga taagtatgaa
    10141 cagcggcttt cggcaaaccg gtagagccgg aggtcaacgt cattgagcac agacgcgtcg
    10201 gctgccacgc agcggcatgt gcgccttcaa ccagctgaat gtgcagcgac gttaacgccg
    10261 gaaacgtgtt ttccccatcc ggcaccagcg caaattgcag cgtcagattg ggcagcaatt
    10321 cttcaagcaa cggttgcggc agctgagggt tcacgggcaa cacccgcgcc ccgcattgca
    10381 gtaacgccag ccaggcgagc agcgtttgcg gcgtattcca cgcccgcaac atcacgccgc
    10441 tgccctcaac aacgccctgc gccgcaaagc cggaggctaa ttcatcgacg cgagcacaaa
    10501 gctcgcgcca gttaagttgc tcgtcattaa gacgtaaggc gatggcttct ccccgcactt
    10561 gccgccagtg acgccacggc cagtcagaga agatcataac agccgctcca gtgcatcaac
    10621 ttccactaac ggtagcgggc tacccggcca gcgacgaacc tgctgcgcct gcatcagatc
    10681 cagcgtgtcc agccccggaa tggtgtctgg cgttaaccag gcggcaatcc gcgccagttg
    10741 cgttaagcct aagctcgact caatagaaga actgatcacc gccgtcagcc ccaacgcgtg
    10801 cgccgcctgc acctgctcac gtactttctc caggctgccc gtgagcgtag gtttgataac
    10861 taccgcgctc acgccctctt cagccacaaa ggcaaaatcc ggctcgcgca ggctttcatc
    10921 ccaggcaatg gcaatgccgg tttcacgggc aaacgcacgg gaatcatcgc gggttttgca
    10981 cggctcttcg agaaacgcga tgcggtggcg ataatccggg ttaacgtatt tggcaaactg
    11041 ctgacctttc agcgacgtcc aggcgcgatt tgcgtcaaga cgcaaatgca gatccggaat
    11101 tgcctccagc aacagattca ccaccatgcc gtcgcgcacc gcttcgtaca atcccacttt
    11161 gaccttcgcc actttctcgc ccggcatatc ggcaagtttg aggatcagat cgtccggatc
    11221 gccattacac agcggtgccg cacggtagtt ggctgcttgc ggcaacgcat cggtcagttc
    11281 tgccaatgca cagcttacgc caaaggccac ggaaggcatc tgcggtagct cgcaatcgcc
    11341 tgccagccag ttatttaccc aggcaagcag cacgctttgc gcctcttccc aggtttcctg
    11401 gctgaagccc ggcagtgggg agatctcccc ccacccttcg cgctcgccct cacgcaggca
    11461 aacatacagc ccgtcgcggg tttttaaccg cctgtcgcgc agaaccaccc ccgcgtccat
    11521 ggggatctgc cagcggtata cctgcgcgct acgcattacg gattccgttt aaatttgctg
    11581 aaatcaggct gacgtttctg gttgaaagcg ttgcgacctt cctgaccttc ttccgtcata
    11641 tagaacagca tggtggcgtt acctgccagc tcctgcagac ctgcctgacc gtcacagtcg
    11701 gcgttcagcg cagctttcag gcagcgcagc gccatcgggc tgttttgcag catttcgcgg
    11761 caccaacgga cggtttcttt ttccagatcc gccagcggta ccacggtgtt cacaaggccc
    11821 atatccagcg cctgtttcgc gtcgtactga cggcacagga accagatttc acgcgctttt
    11881 ttctgtccga cgatgcgagc catgtaggaa gcgccccagc cgccgtcgaa ggaaccgact
    11941 ttcgggccag tctggccgaa gatggcatta tcagccgcga tagtcaggtc gcacatcatg
    12001 tgcagaacgt gaccgccgcc gatggagtag ccagccacca tcgcgacaac cggtttcgga
    12061 caggtacgaa tctgacgctg gaagtccagc acgttcaggt gatgtacgcc ggaatcatct
    12121 ttatagccgc cgtaatcacc acgcactttc tggtcaccac cggagcagaa cgctttatcg
    12181 cctgcgccag tcagaatgat cacgccgatg ttgtcgtcat aacgcgcatc tgccagtgcc
    12241 tggatcatct cttttaccgt cagaggacgg aaggcattgc gcacctgcgg acgattaatg
    12301 gtgatttttg cgataccgtc ggcagatttt tcataacgaa tgtcctcgaa accttcggag
    12361 cagtcgtgcc attcaaccgg tgcgtaaagc attgcttcat caggataaat catattgtgt
    12421 cctttagtca gaaacgcaag atctgcgcca gacttgcgat tacgccagcg ggattttccc
    12481 gatgcgcgtt atgtccggcg cgaggaatga catggcattc ggcagccagt tccgccgcca
    12541 gggcgcggaa tttgctgtca cgttcaccac ataaataata aaacgcaaat gtgcgggcgc
    12601 taaggttagc acgtaaatcg ggctggacgg cgagagaagt cgcctccagc atggcggcaa
    12661 gcgttgcgcc attattgttg ctgcgcagcg caaccagctc ccggcgttgt tcgtcattga
    12721 gtgaggcaaa aacaggctgt tgataccagt cagcaaatac cgccgttaac ggttctgtgc
    12781 gaaaacgctg cgcccattgg cgatcggaac gctgacgttc cgtgcgttgt tcagcatttt
    12841 gcaacccagg gtgcccgcct tcgacaataa ccccacaaag ccccggcatc ccctgacaag
    12901 ccgccatcat cgccacccgt ccgccaagcg agtaccccac cagccagaag ttaaggatgt
    12961 tgtaactaac cagagttttg cgcagtaagc cggtgacatc atcaaatcca tcgacgcgaa
    13021 tcgccgccga accaccgtga cctgggagat caacatacaa ccgcgagtag ttggcaaaca
    13081 cctcgcccac ttcttgccat tcatggcaat cgccggaaaa accgtgcaaa aacaccagcc
    13141 agggtaaacc tggtttaccg tgttttgcct gcgcgtgcag gatcataaat ggctaacctg
    13201 cgccagcagt tgctggaggg tttgcgcacc attggtgtcg ttaaccacca tttcaattac
    13261 cgtggtggtc ggcgtgcgcc aggcgtcggc aagtgccgtt tcaagttcct gccagttttg
    13321 cggacaatga tatttcagct cgaacatcgc ggcggcgtgc tcaaaatgga cgttttgcgg
    13381 catcagatag aaacgctcgc gctcgttttt cggcgttggc aacagcgaga aaatttgccc
    13441 gccattgttg ttcaccacaa ttaataccag cggcgcggaa acctgacgta ataacgccag
    13501 cgcgttgaga tcgtaaagtg ctgagagatc gcccacaatc gccagcgtcg gtttgccact
    13561 ggcccgctga acgccagcag cagttgagag cagcccgtcg ataccgctgg cacctcggtt
    13621 gctgtacacc gggtaacctg ccggaagttg cgaaagcgca tcaatcagac gtaccaccag
    13681 gctgttaccg acaaacaatt gcccctgttc aggcaaatag tcgctgatgc gatgcgccag
    13741 ttgcgcttcg ccaaacgcat cgcgacgggc aataaccgcc tgcattgcct gttcagccag
    13801 gcgcgggatt tcaacgcacc agggctggcg tttttctgcc ggatgttgct ccagccagtc
    13861 ggcaatattg gcaattaagc gacgtccgcg atggtgtgcc ggatcaagtc gcccttcaat
    13921 gtcatcaaca atccagtact cttcgggttc acagcttgcc tgccattgca ggagccgttt
    13981 gcccgtcagg ctgcttccca gttgcaccac aatttgcgcc tgttgcagtt cgctggtcgc
    14041 tttggcattg cctaaccaga gatcggcaca cggcagcggc tgtccggttt gcgacagcac
    14101 atcgccaatc agcggccagc caagagtttg cgcccacagt gcgacttttt tgccctcttc
    14161 cgcactcatg cgcccggcaa ccaccacgcc gcgcttttgt cgccagaaga accagtcgcg
    14221 ctgtttttca ctttccagac gaggcgcttc acgcaaccac ggtttgtcgt cctgccacca
    14281 gtcgcccaga cgctgttgcc agctaagccc ggtgtcgtcc atttcgccat acagcggttc
    14341 agcaaacggg cagttgatat ggactccacc agcatgaagc gtaccgagag cgtggtcgat
    14401 ggtagaaacc agccaacgtg cggggatatc ctgggtcggg cgcggcagtg aaatactgtg
    14461 cgtggggtga gaggcgaaca ttcccggctg acgaatcgcc tgattcgcgc cgcagtcaat
    14521 tagctccggc gggcgatcgg cggttaacag gatcagtttt tctccggtta acccggcttc
    14581 aatcagtgcc ggatagagat ttgctaccgc cgtgccggag gtcacaatca cagccaccgg
    14641 ctgcttgctg actttcgcca gccccagcgc cagatgcccc agtccacgct catcgaaatg
    14701 ggtgtggtga atgaatgcgg aattctccgc cgccgctaac gttaacggtg tagaacgcga
    14761 gccaggggcg atacagatgt gtctgacgcc gtgacgcgtt aatgcttcca gaatgaccgc
    14821 cgcccagcgt cggttaaatg cgcttactga catgagtttg tccggtatca atattgcggc
    14881 taagtataag gagctacaaa aatagattat tgatatgaat cggtaatgat gcgactcatt
    14941 actattccat ttgtaataaa gtacgcagcc ctgccgcttt gttgtcgatt tcctgccact
    15001 cttgctcggg gtcggaacca cggacaatgc ccgcgccagc atatagtcgc acgacattgc
    15061 cgctaatttt tgctgagcgc agggaaacgc agaattcgct ttgttgtaaa gagagatagc
    15121 ccgcagaacc ggcgtaccat tctcgggtga acggttcgtg acgggcgata aactgtcgcg
    15181 ccagatcgcg cggtaagcca gcaactgctg ccgttggctg caactgatgt aaacagatca
    15241 catcatccgc tttgttgagt gcagtccaga tacagcggcg aagatgctgc actttacgca
    15301 gacgcagtac ctgcggcggt aaaacatcca gcgtcagggt atcggcctgc aatcgttggc
    15361 agatatcctc caccaccaac atgttctcgc gctggttttt atcatccgcc atcagccact
    15421 cacctaactg ctgcgcctgc ttatcatcag gatgatttgc taccgttccc gccagcgctt
    15481 cggtacgcag cgctttgtca cgccgccgcc ataaccgttc cggtgaagaa ccaagaaaag
    15541 cattttcgcc atcaaaggcc atgtaaaaat ggtagcaatt cagattgagc cgacgactgg
    15601 cagccatcat cgctgccgca ttgaccggac ttgcgaaatg caggtcagtt gcccgagcaa
    15661 gcaccacttt gtcgagctca ccttcggcga tggttttcgt tgccagttcg attaattgcg
    15721 tccagcccgt tttgtccggc cagtgttgtt ctcgcgtggt ggttaaatgt aacccaggca
    15781 agggcttgat actcaccagt ttggcgataa attcttttgc cttgattgca tcgtgctgaa
    15841 gggagctttc gctgaatagc gtcaccctca gcgtggcttt accgccacag cgtcgccatt
    15901 cgaggcgtgg taaaagtaaa ttaccctgcg acgggtcaaa cgcattcagc ccccagatgc
    15961 gtaagtcggc gtgttccggg tgctggcgaa gaaaacgttg tgcctggtcc aacgacgtaa
    16021 aacgggtaat cgcacccagg acggcagctt cttcatcacc attacgttgt tgccagtaga
    16081 attgcggata cgtttgctga ctggccagcc agctcaaggc atcaaaagcg tctttgagag
    16141 ggaaaggaat atcgataacc cgaatgccgg gtgtcgccgg aatctcttgc gacaaatggc
    16201 gcagtagatt ttccagcgcc gtagtaagtg attgcacgcg gacctctccc tgttaaaagc
    16261 ctcacattat acggggtact acaaaaaaaa tgcagtaccc cggtgtaggg aggttttaac
    16321 ggcgtgccag caacagtcct agtaccagcc caacggccgc gcccacacca attccttgcc
    16381 agggtttttc gtggacgtag tcatcagcac gataaacagc ctgcttcgcc cgatagtaat
    16441 aactgtctga agcctggcta acccgttttt tcacatcatc cagcgctttt tctgcacgcg
    16501 ctttcagctc aacatatttc tgatcggcgg gatcgccaga ggagcggagc acctcttcca
    16561 gtgtttcact aagcagcgtc aggtcatcat cgatacgtgt atcaccaaac tgattagaca
    16621 ttctcgttct ccatttgcgt aaaacctgtc actaactata gacaagggtt attgattacg
    16681 cctgaattac ctcgcgtgcc atcccaatgt gtgggatacc atcttcttca tagacctccg
    16741 tcacagggat aaagccaaaa ctctggtaga agttttgcag atgcgcctgc gccccgaggt
    16801 aaacaggttt atcaggccag tgacgcgtac atgtttcgag tgttttattc atcagctgct
    16861 gccccacttt ttcgccacgc aacgcttcac taacaatcac ccgaccaata acgaccggct
    16921 caagatcatc atcacttttc agaatcctcg catacgccac cagttcatca tttttccaac
    16981 cgagaatatg gcgattatcc cccgtcaaat catcaccatc gatatcctga taagggcaat
    17041 tctgctcaac aacaaacacc gcgcaacgca gttgtaataa ggcataaagc tgggaaaccg
    17101 ataattcaga gtgatgcaga tcttgccatt caatcataat gctctccttt tagatgtatg
    17161 ccttatacta gccggaatat tttttgaaac gtgatgaact catggaatta atttttttag
    17221 gtacttcagc cggtgtgcca acccgtacgc gcaatgtcac ggcaatattg cttaacctgc
    17281 aacatccgac ccagagcggt ctttggttgt ttgactgcgg tgaaggcacc cagcatcagc
    17341 tactgcatac cgcctttaac cctggaaaac tggataagat ttttatcagc caccttcatg
    17401 gcgatcatct ctttggttta cccggcttgc tgtgcagtcg ttctatgtca ggcattatcc
    17461 aacccttaac gatttatggt ccgcaaggta tccgtgaatt tgtggagact gcgctgcgga
    17521 ttagcggctc atggaccgat tatccgctgg aaattgtcga aattggcgct ggcgaaattc
    17581 tcgatgatgg cctgcgcaaa gtgaccgctt atccgatgga acacccactg gaatgttatg
    17641 gctatcgtat tgaagaacat gataaaccgg gtgcattaaa tgcccaggca ttaaaagctg
    17701 ctggcgtgcc gcctggccca ctgtttcagg cattaaaagc gggcaaaaca atcacgctgg
    17761 aagacggaag gcagattaac ggcgcagatt acttagccgc tccagtgcca ggtaaagcgc
    17821 tcgctatttt cggcgatacc ggcccctgcg atgccgcact tgacctggct aaaggtgtcg
    17881 atgtcatggt gcacgaagcg acgctggata taaccatgga agccaaagcc aatagtcgcg
    17941 gccatagctc tacacgccag gctgcgacac tagcccgtga ggctggagtc ggtaagctaa
    18001 tcattaccca cgtcagctcg cgctatgatg acaaaggttg tcagcacctg ttacgtgaat
    18061 gtcggtcaat tttcccggcg actgaactgg cgaatgattt caccgtgttt aacgtttaac
    18121 tctgcttact actaaaaaca gggcgaaact tgccctgtta tcgcaacccg cgctacatat
    18181 atccacccac acgggaatat tgagcgattt ttgatattta ttcatctcct cacgcactat
    18241 attcagagca ataagttgcc tctttttatc ttcattcagc acaacctttg caactaaaag
    18301 gagcctatga tggttacagt tgtcagcaat tattgtcaat tatctcaaac ccaactctgt
    18361 cagacatttg cagaaaaatt tactgtgacc gaggaattac tgcagtcttt aaaaaaaaca
    18421 gcgttatccg gggatgaaga aagtattgag ttactgcata acattgcgtt aggttatgat
    18481 gaatttggga aaaaagctga agatattctt taccatattg ttagaaaccc aacaaatgag
    18541 accctatcga ttatccgact tattaaaaat gcctgtttaa aattatataa tttggcacat
    18601 accgcaacca c
//
LOCUS       DACAOP010000090        18039 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.090, whole genome shotgun sequence.
ACCESSION   DACAOP010000090 DACAOP010000000
VERSION     DACAOP010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18039
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.090"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            118..1203
                     /gene="dmlA"
                     /locus_tag="IT892_003441"
     CDS             118..1203
                     /gene="dmlA"
                     /locus_tag="IT892_003441"
                     /EC_number="1.1.1.83"
                     /EC_number="1.1.1.85"
                     /EC_number="1.1.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional
                     D-malate/3-isopropylmalate/tartarate dehydrogenase"
                     /protein_id="HAP3136622.1"
                     /translation="MMKTMRIAAIPGDGIGKEVLPEGIRVLQAAAERWGFALSFEQME
                     WASCEYYSHHGKMMPDDWHEQLSRFDAIYFGAVGWPDTVPDHISLWGSLLKFRREFDQ
                     YVNLRPVRLFPGVPCPLAGKQPGDIDFYVVRENTEGEYSSLGGRVNEGTEHEVVIQES
                     VFTRRGVDRILRYAFELAQSRPRKTLTSATKSNGLAISMPYWDERVEAMAENYPEIRW
                     DKQHIDILCARFVMQPERFDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERTFP
                     SLFEPVHGSAPDIYGKNIANPIATIWAGAMMLDFLGNGDERFQQAHNGILAAIEEVIA
                     HGPKTPDMKGNATTPQVADAICKIILR"
     gene            1394..2839
                     /locus_tag="IT892_003442"
     CDS             1394..2839
                     /locus_tag="IT892_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HAP3136623.1"
                     /translation="MVLLAMGLVIYLATSKYGNIRLGEGKPEYSTLSWLFMFICAGLG
                     SSTLYWGVAEWAYYYQTPGLNIAPRSQQALEFSVPYSFFHWGISAWATYTLASLIMAY
                     HFHVRKNKGLSLSGIIAAITGVRPQGPWGKLVDLMFLIATVGALTISLVVTAATFTRG
                     LSALTGLPDNFTVQAFVILLSGGIFCLSSWIGINNGLQRLSKMVGWGAFLLPLLVLIV
                     GPTEFITNSIINAIGLTTQNFLQMSLFTDPLGDGSFTRNWTVFYWLWWISYTPGVAMF
                     VTRVSRGRKIKEVIWGLILGSTVGCWFFFGVMESYAIHQFINGVINVPQVLETLGGET
                     AVQQVLMSLPAGKLFLAAYLGVMIIFLASHMDAVAYTMAATSTRNLQEGDDPDRGLRL
                     FWCVVITLIPLSILFTGASLETMKTTVVLTALPFLVILLVKVGGFIRWLKQDYADIPA
                     HQVEHYLPQTPVEALEKTPVLPAGTVFKGDN"
     gene            2871..3995
                     /gene="yeaW"
                     /locus_tag="IT892_003443"
     CDS             2871..3995
                     /gene="yeaW"
                     /locus_tag="IT892_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase subunit YeaW"
                     /protein_id="HAP3136624.1"
                     /translation="MSNLSPDFVLPENFCANPQEAWTIPARFYTDQNAFEHEKENVFA
                     KSWICVAHSSELANANDYVTREIIGESIVLVRGRDKVLRAFYNVCPHRGHQLLSGEGK
                     AKNVITCPYHAWAFKLDGNLAHARNCENVANFDSDKAQLVPVRLEEYAGFVFINMDPN
                     ATSVEDQLPGLGAKVLEACPEVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPG
                     FSDSVQVDRYWHTMHGNWTLQYGFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPI
                     KGMMTVIYEFPVDSETTLQNYDIYFTNEELTDEQKSLIEWYRDVFRPEDLRLVESVQK
                     GLKSRGYRGQGRIMADSSGSGISEHGIAHFHNLLAQVFKD"
     gene            4051..5016
                     /gene="yeaX"
                     /locus_tag="IT892_003444"
     CDS             4051..5016
                     /gene="yeaX"
                     /locus_tag="IT892_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase subunit YeaX"
                     /protein_id="HAP3136625.1"
                     /translation="MSDYQMFEVQVSQVEPLTEQVKRFTLVATDGKPLPAFTGGSHVI
                     VQMSDGDNQYSNAYSLLSSPHDTSCYQIAVRLEENSRGGSRFLHQQVKVGDRLTISTP
                     NNLFALIPSARKHLFIAGGIGITPFLSHMAELQHSDVDWQLHYCSRNPESCAFRDELV
                     QHPQAEKVHLHHSSTGTRLELARLLADIEPGTHVYTCGPEALIEAVRSEAARLDIAAD
                     TLHFEQFAIEDKTGDAFTLVLARSGKEFVVPEEMTILQVIENNKAAKVECLCREGVCG
                     TCETAILEGEADHRDQYFSDEERASQQSMLICCSRAKGKRLVLDL"
     gene            complement(5070..6185)
                     /gene="rnd"
                     /locus_tag="IT892_003445"
     CDS             complement(5070..6185)
                     /gene="rnd"
                     /locus_tag="IT892_003445"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707318.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HAP3136626.1"
                     /translation="MITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFD
                     GEHLALIDPLGITDWSPLKAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQIL
                     AAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLLPITA
                     KLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLAD
                     WRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVE
                     KAQTLPEDALPQPMLNLMDMPGYRKAFKAIKSLITDVSETHKISAELLASRRQINQLL
                     NWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYPQ"
     gene            complement(6267..7952)
                     /gene="fadD"
                     /locus_tag="IT892_003446"
     CDS             complement(6267..7952)
                     /gene="fadD"
                     /locus_tag="IT892_003446"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase FadD"
                     /protein_id="HAP3136627.1"
                     /translation="MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVN
                     MGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVV
                     NVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAK
                     GTVVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTT
                     GVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELG
                     GQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGG
                     MPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLV
                     DDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRI
                     VDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSL
                     TEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA"
     gene            complement(8158..8739)
                     /gene="yeaY"
                     /locus_tag="IT892_003447"
     CDS             complement(8158..8739)
                     /gene="yeaY"
                     /locus_tag="IT892_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein YeaY"
                     /protein_id="HAP3136628.1"
                     /translation="MAVQKNVIKGILAGTFALMLSGCVTVPDAIKGSSPTPQQDLVRV
                     MSAPQLYVGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPTLGEPSRGRIYADVN
                     GFLDPVDFRGQLVTVVGPITGAVDGKIGNTPYKFMVMQVTGYKRWHLTQQVIMPPQPI
                     DPWFYGGRGWPYGYGGWGWYNPGPARVQTVVTE"
     gene            complement(8779..9474)
                     /gene="tsaB"
                     /locus_tag="IT892_003448"
     CDS             complement(8779..9474)
                     /gene="tsaB"
                     /locus_tag="IT892_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAP3136629.1"
                     /translation="MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQD
                     ILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGA
                     WRKNGATRVLAAIDARMGEVYWAEYQRDENGIWHGEETEAVLKPEIVHERMQQLSGEW
                     VTVGTGWQAWPDLGKESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYL
                     RNNVAWKKLPGKE"
     gene            complement(9532..11442)
                     /locus_tag="IT892_003449"
     CDS             complement(9532..11442)
                     /locus_tag="IT892_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAP3136630.1"
                     /translation="MTDDFAPDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVE
                     AGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLYSRDLPTVSKALKYTGNVALLKG
                     RSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTVDGDISTCVSVAEDSQAWPL
                     VTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADMVVKESGFGELIPE
                     ADVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLA
                     QSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYDVAKLSLGRSALLDA
                     AFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKPGSW
                     IFTSATLSVNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVPRNLPQTNQPGSAR
                     QLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFV
                     SAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFD
                     EVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIA
                     RAVRFLAIPSSR"
     gene            11574..11918
                     /locus_tag="IT892_003450"
     CDS             11574..11918
                     /locus_tag="IT892_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416323.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HAP3136631.1"
                     /translation="MTIVRIDAEARWSDVVIHNNTLYYTGVPENLDADAFEQTANTLA
                     QIDAVLEKQGSNKSSILDATIFLADKNDFAAMNKAWDAWVVAGHAPVRCTVQAGLMNP
                     KYKVEIKIVAAV"
     gene            12280..12639
                     /locus_tag="IT892_003451"
     CDS             12280..12639
                     /locus_tag="IT892_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1889 family protein"
                     /protein_id="HAP3136632.1"
                     /translation="MQIKVIYSLIDNMVNFKDKNMPAVIDKALDFIGAMDVSAPTPSS
                     MNESTAKGIFKYLKELGVPASAADITARADQEGWNPGFTEKMVGWAKKMETGERSVIK
                     NPEYFSTYMQEELKALV"
     gene            complement(12759..12938)
                     /locus_tag="IT892_003452"
     CDS             complement(12759..12938)
                     /locus_tag="IT892_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaH family protein"
                     /protein_id="HAP3136633.1"
                     /translation="MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRAN
                     HSGERIVARFEDEDE"
     gene            13012..14373
                     /gene="pabB"
                     /locus_tag="IT892_003453"
     CDS             13012..14373
                     /gene="pabB"
                     /locus_tag="IT892_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 1"
                     /protein_id="HAP3136634.1"
                     /translation="MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYS
                     RFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPF
                     QGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDV
                     NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRF
                     HATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGT
                     LPRLPDPQEDSKQAVKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPF
                     PAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCG
                     SIGYLSFCGNMDTSITIRTLTAINGQIFCSAGGGIVADSQEEAEYQETFDKVNRILKQ
                     LEK"
     gene            14377..14955
                     /locus_tag="IT892_003454"
     CDS             14377..14955
                     /locus_tag="IT892_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HAP3136635.1"
                     /translation="MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQP
                     GLLLTQRSIHLRKHAGQVAFPGGAVDDTDASAIAAALREAEEEVAIPPSAVEVIGVLP
                     PVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDS
                     HRVWLSWYEQYFVWGMTAGIIRELALQIGVKP"
     gene            15139..16503
                     /locus_tag="IT892_003455"
     CDS             15139..16503
                     /locus_tag="IT892_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine dehydratase 1"
                     /protein_id="HAP3136636.1"
                     /translation="MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDSVTR
                     VAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVEERERLLLAQGR
                     HEVDFPRDNGMRFHNGNLPLHENGMQIHAYNGDEVVYSKTYYSIGGGFIVDEEHFGQD
                     AANEVSVPYPFKSATELLAYCNETGYSLSGLAMQNELALHSKKEIDEYFAHVWQTMQA
                     CIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFMAAGAIGALYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGGSPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAINAARMALRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIK
                     VQCD"
     gene            16634..>18039
                     /locus_tag="IT892_003456"
     CDS             16634..>18039
                     /locus_tag="IT892_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAP3136637.1"
                     /translation="MQKAQRIIKTYRRNRMIVCTICALVTLASTLSVRFISQRNLNQQ
                     RVVQFANHAVEELDKVLLPLQAGSEVLLPLIGLPCSVAHLPLRKQAAKLQTVRSIGLV
                     QDGTLYCSSIFGYRNVPVVDILAELPAPQPLLRLTIDRALIKGSPVLIQWTPAAGSSN
                     AGVMEMINIDLLTAMLLEPQLPQISSASLTVDKRHLLYGNGLVDSLPQPEDNENYQVS
                     SQRFPFTINVNGPGATALAWHYLPTQLPLAVLLSLLVGYIAWLATAYRMSFSREINLG
                     LAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGWISPDVFIPIAEEHHLIVPLTR
                     YVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITE
                     RDALLDVDYRIARELHRKNVKLAIDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSD
                     AVNSTVTDIIIALGQRLN"
BASE COUNT         4272 a         4697 c         4546 g         4524 t
ORIGIN      
        1 cggtaaatta ttcatgattc gtgttttatg tttcaccagt tacggggatt aattcctttt
       61 cagtcaatta taggatggtg atgttgtcaa ttttgatggt caggaagtga gaacccaatg
      121 atgaaaacga tgcgtattgc tgcgatcccg ggagacggga ttggcaaaga agtccttcct
      181 gaagggattc gcgtgttaca ggctgccgct gagcgctggg gcttcgcctt gagttttgag
      241 caaatggagt gggcgagctg cgagtattac agccatcacg gtaaaatgat gccggacgac
      301 tggcatgagc aacttagccg tttcgacgcc atctattttg gtgccgtcgg ctggccggat
      361 accgttccgg accatatttc gttgtggggt tcgctgctga aatttcgtcg tgaattcgac
      421 cagtacgtca acctgcgccc ggttcgtctc tttcctggcg ttccctgccc gctggcggga
      481 aaacagcctg gcgacatcga tttttacgtg gtcagggaaa acaccgaagg cgaatattcc
      541 tcgctcggcg gtagagtgaa tgaaggtaca gagcatgaag tcgtcattca ggaatcggta
      601 tttacccgcc gtggtgtcga tcgcattttg cgttatgcct tcgaacttgc gcaaagccgt
      661 ccacgtaaga cactaacttc tgccactaaa tcgaacggtt tagccatcag catgccgtac
      721 tgggatgagc gagtggaagc aatggccgag aattacccgg agatccgctg ggacaagcag
      781 catattgata ttctctgcgc gcgttttgtg atgcagccgg aacgattcga tgtggtggtg
      841 gcgtccaatt tgtttggcga tatcctttcc gatcttggcc cggcctgcac cggcaccatt
      901 ggcattgccc catccgccaa cctgaatccg gaacgcactt tcccgtcgct cttcgagcct
      961 gtccacggtt ccgcgccgga tatctacggg aaaaatattg ctaaccctat cgccacgatt
     1021 tgggccgggg caatgatgct cgattttctc ggcaatggcg atgagcgttt ccagcaagcg
     1081 cataacggta ttctggcagc aattgaagaa gtgattgctc acgggccgaa aacacctgat
     1141 atgaaaggca atgccaccac gccacaggtt gccgacgcga tttgcaaaat tattttgcgt
     1201 taaggtcaaa ccagtttatt tgaaccgcgt cactgacgcg gtttttttat tcgttctttg
     1261 cagtaaataa cctgcgtcat ttcacctttt attgtttccg tttcgtgttt tatggctttc
     1321 cgtattctta attgtttaat ttatgtaaca tgcaaatttt gttacgcgta cgttaggttc
     1381 cgccgtacag gtattggttt tgctggcaat gggactggtg atttatttag ccaccagtaa
     1441 atacggcaat attcgtcttg gcgaaggaaa accggaatac agcacgctct cctggctgtt
     1501 tatgtttatt tgtgccggtt taggttcttc tacgctttat tggggggttg ctgaatgggc
     1561 ctattattat caaacacctg gattaaatat cgcaccgcgt tcacaacagg cactcgaatt
     1621 tagcgttccc tactctttct tccactgggg catcagcgcc tgggcaactt atacgctggc
     1681 ctcattaatc atggcttatc actttcatgt gcggaaaaac aaaggtctga gcctttccgg
     1741 cattattgct gctattaccg gcgttcgccc gcaaggccca tggggaaaac tggtcgattt
     1801 gatgttcctg atcgccactg tcggcgcact gaccatttcc cttgttgtta ccgcagcaac
     1861 ctttacccgt gggctttccg cgctgaccgg tttacccgat aacttcaccg tgcaggcatt
     1921 tgtgatcctg ctttccggcg gcattttttg cctaagctcg tggattggta tcaacaacgg
     1981 tttgcaacgt ctgagcaaaa tggttggctg gggcgcgttc ctgctgccat tactggtgct
     2041 gattgtcggc ccaaccgaat ttattaccaa cagcatcatc aatgccatcg gcctgaccac
     2101 gcaaaacttc ctgcaaatga gcttattcac cgatccgctt ggcgatggtt catttacccg
     2161 caactggacc gttttctact ggctgtggtg gatctcatac acccctggcg tagcaatgtt
     2221 tgtcacccgc gtttcccgcg gtcgtaagat taaagaagtt atctggggac tgatcctcgg
     2281 cagcaccgtc ggttgctggt tcttctttgg cgtaatggaa agctatgcca ttcatcagtt
     2341 tatcaatggc gtaatcaacg tcccacaggt gctggaaaca ctgggcggcg aaacagctgt
     2401 acagcaagtt ctgatgtcgt tgccagccgg taaattgttc ctcgccgcat acctgggcgt
     2461 gatgattatt ttccttgcct cgcatatgga tgcagtggcc tacaccatgg cggcgaccag
     2521 tacgcgtaat ctccaggaag gtgacgatcc tgaccgtggg ctgcgtcttt tctggtgcgt
     2581 ggtgatcact ctgatcccgc tttccatctt gtttaccggt gcttcgctgg aaacgatgaa
     2641 aaccaccgtc gtgctcacag cccttccctt cctcgtcatt ttactggtga aagtcggcgg
     2701 gtttattcgc tggctgaaac aggattacgc cgacattccg gctcatcaag ttgaacatta
     2761 tctcccgcag acaccggttg aagccctgga aaaaacgcca gtgctccctg cgggaaccgt
     2821 attcaaaggc gacaactgag cgccatcatc ctaacgataa aggtatccct atgagcaatc
     2881 tgagccctga ctttgtacta cccgaaaatt tttgcgctaa cccgcaagag gcgtggacca
     2941 ttcctgcccg tttttatacc gatcagaacg cgtttgaaca cgaaaaagag aacgtcttcg
     3001 ccaaaagctg gatttgcgtc gctcacagca gcgaactggc gaatgccaat gattatgtga
     3061 cgcgtgagat cattggcgaa agcatcgtgc tggtacgcgg tcgtgataag gttttgcgcg
     3121 cgttctataa cgtgtgtccg caccgtggtc atcagttgtt gagcggtgaa ggaaaagcaa
     3181 aaaatgtgat tacctgcccg tatcacgcat gggcattcaa actcgatggc aacctggccc
     3241 atgcacgtaa ctgcgaaaac gtcgccaatt tcgatagcga caaagcgcaa ctggttccgg
     3301 tgcgtctgga agaatatgcc ggattcgtct tcatcaacat ggaccccaac gccaccagcg
     3361 tagaagatca attacccggc ctgggcgcga aagtgctgga agcctgcccg gaagtccacg
     3421 atctgaaact ggcggcccgc tttaccaccc gcacgcctgc caactggaag aacattgtcg
     3481 ataactatct cgagtgctat cactgtggtc cggcgcatcc aggtttctcc gactccgtac
     3541 aggttgatcg ttactggcac accatgcacg gtaactggac gctgcaatac ggtttcgcca
     3601 aaccgtccga acagtcgttt aaatttgaag agggtacgga tgcggcattc cacggtttct
     3661 ggctgtggcc gtgcacgatg ctgaacgtca ccccgatcaa agggatgatg acggtcattt
     3721 atgaattccc ggtggattct gaaactaccc tgcaaaacta cgatatttac ttcaccaatg
     3781 aagagttaac cgacgagcaa aaatcgctga ttgagtggta tcgcgatgtg ttccgtccgg
     3841 aagatttacg tctggttgaa agcgtacaga aagggctgaa atcgcgtggc tatcgtggtc
     3901 aggggcgcat catggccgac agtagcggta gtggcatttc cgaacatggt atcgcccatt
     3961 tccataatct gctggcgcag gtgtttaagg actaatgaca tcggcggcgg tattttccgc
     4021 cgctgggctg atttttgatg gagtacagca atgtcagact atcaaatgtt tgaagtacag
     4081 gtgagccagg ttgaacccct taccgaacag gtgaaacgct tcacgctggt ggcaaccgat
     4141 ggcaaaccat tacctgcgtt taccggagga agtcacgtca ttgtgcagat gagcgatggt
     4201 gataaccagt acagcaatgc gtattcacta ctgagttcgc cgcatgacac ctcttgttat
     4261 cagattgccg ttcggctgga ggaaaactcg cgcggcggtt cccgcttttt gcatcagcag
     4321 gtaaaagtgg gcgatcggtt aacgatttca acgcctaata acctgtttgc gctaattccc
     4381 tcagccagaa agcatctgtt tatcgcgggc ggtattggta tcaccccttt cctgtcgcac
     4441 atggcagagc tgcaacacag cgacgtcgac tggcagctac attactgctc gcgaaatcca
     4501 gaaagttgcg catttcgtga tgagctagtc cagcatccgc aggctgagaa agtccatttg
     4561 catcattcat caaccggaac acgactggaa ttagcgcgat tattggcgga tatcgaacct
     4621 ggcacacacg tttatacctg tggccccgag gcgctaattg aagcggtaag aagtgaagct
     4681 gcgcgtctgg acatcgccgc cgatacgctg cactttgagc aatttgctat cgaagacaaa
     4741 accggcgatg catttaccct ggtgcttgcc cgttccggaa aagagtttgt ggtgccggaa
     4801 gagatgacta ttttgcaggt tattgaaaat aataaagccg cgaaagtgga atgtttatgt
     4861 cgtgaagggg tatgcggaac ctgcgaaaca gcaatactgg aaggtgaagc tgaccatcgg
     4921 gatcaatatt ttagcgatga agagcgtgcc agccagcaaa gtatgttgat ctgttgttcg
     4981 cgtgcgaagg gtaaacgcct ggtgttggat ttgtagtttg ccgaagccgg atgtggcgct
     5041 gagcgcgccc agtccggctt cggaagattt tactgcggat attcctgcaa taaattgtgt
     5101 aatgcttccg ccatcagctc accacgccag ccggaaatca gctccggcaa attgttctgc
     5161 ggtttcagtt tccagtgcca gttcagcagt tggttgattt gccgacgcga tgccagcaat
     5221 tcggcgctga tcttatgcgt ttcgctcacg tcagtaatca gcgacttaat cgctttaaac
     5281 gctttacgat aacccggcat gtccatcagg ttaagcatcg gctgcggtaa ggcatcttcc
     5341 ggcaatgtct gcgctttttc caccagcgct agcagcgttt taccgtgaaa gcggatttcg
     5401 ctaccggata aacccaggct gtccagttcg cctaaacttc ccggcatata acgcgctacc
     5461 gaccacaaat gctcttcacg cacgacaaag ttcaccgcca gatcgcgctc tcgcgccttg
     5521 cgcagtcgcc agtcggctaa cagttgcaga caggccagtt ggcgtgtgcg taattgccag
     5581 gcattggtga tatcacgcca ggcatcttcc ggcgcaacga cttcctgacg acgcatttgc
     5641 atcaggcggc attcatccag cgccgcaggt agccagccgg aggcctccgt ttctaccata
     5701 agcttggcgg tgatcggtaa cagataccag acatccgccg ctgcgtattc acactgacgt
     5761 tcggtcagcg gtctggccag ccagtcggtg cgcgattcac tcttgtccag cgtaacgccg
     5821 gaatactctt ccaccatgga agcgaaaccc catgacatcg ggcgtccgca gaaggcagca
     5881 aggatttgcg tgtcaatcaa gggttgtggt aattcgccaa agacattgag gaacacttcc
     5941 agatcttcac tgcctgcatg gagaaatttt gtgatggacg gatcgcgcag gatcgctttc
     6001 agcggtgacc agtcggtgat cccgagtgga tcgattagcg ccagatgctc gccatcgaaa
     6061 agttgaatca accccagttg cgggtaataa gtgcgcgtac gaacaaattc agtatccagg
     6121 gctatcgccg gaaaggcacg gacggcttca cacaaagaag ccagcgcatc gtccgtggta
     6181 atcatttggt aattcaaatt gttttctctt tagtgggcgt caaaaaaaac gccggattaa
     6241 ccggcgtctg acgactgact taacgctcag gctttattgt ccactttgcc gcgcgcttcg
     6301 tcacgtaatt ctcgtcgcaa aatttttccg acgttagatt tcggtaactc atcacgaaac
     6361 tccaccagct tcggtacttt gtatcccgtg agctgacggc ggcaaaaagt caccagtgac
     6421 tcttcggtaa gcgatggatc ttttttcact acgaagattt tcaccgcttc accactggag
     6481 ccggaaggta cgccaacagc cgcgacttcc tgtacgccag gatgctgcat gacgacatct
     6541 tcaatctcgt tgggatagac gttaaaaccg gaaaccagaa tcatgtcttt tttacgatcg
     6601 acaatgcgca ggaatccttc ttcatccatt accgcgatgt cgccggtgtg taaccagcca
     6661 tttttgatga tttcatcggt agcatcggga cgctgccagt aacccagcat cacctgcggt
     6721 cctttgacac aaagctcacc cggttgacct ggtggtactt cattatcatc atcatccacc
     6781 agtttggctt ccgtcgacgg caccggcaaa ccgatgctac cactatgata atcaatatca
     6841 tatgggttaa cgctgaccag cggcgcacac tcggtaaggc catagccttc cagcagatac
     6901 tgtccggtca gtttcaccca acgctctgcc accacttgct gcactggcat cccaccgcct
     6961 gcggaaagat gcagactgga gaaatccagc tgctggaact ctttattgtt cagcaacgca
     7021 ttgaacaagg tgttaacgcc cgtgatagcg gtaaacggat atttcgctaa ctcttttacc
     7081 aaccctggaa tatcgcgcgg gttagtgata agcaggttct gcccacccag ttcgataaac
     7141 agcaggcagt taatggtcag ggcaaaaatg tgatacagcg gcagcgccgt caccaccagc
     7201 tctttgcccg gatgcaacag cggaccatag gtcgcgttaa cctgttccag gttcgccagc
     7261 atattgcggt gagtcagcat cgcgcctttc gccacaccag tggtgccgcc ggtgtattgc
     7321 agaaaagcta aatcttccgg caccagttcg ggtttgacgt actgcatccg gtagccgtta
     7381 tgcagtgcgc tacgaaatga aatggcatct ggcagatggt atttcggcac caaacgcttg
     7441 atgtatttaa caacgaaatt gactaccgtg ccttttgccg tagatagctg atcgcccata
     7501 cgggtcagaa ttacgtgctg aacggcggtt ttatcaacca ctttttccag tgtgtgagca
     7561 aagttagaca cgataacaat cgccgatgcg ccgctatcgt taagctgatg ctcaagctca
     7621 cgcggggtat acaacgggtt aacgtttacg acgatcatcc cggcacgcaa aatgccaaac
     7681 agcgccaccg gatattgcaa taaattaggc atcatcaacg caacgcgatc gcctttcttc
     7741 agccccaacc cttgttgcaa ataagcggca aacgcgcgac tgcgttcttc cagcttgcgg
     7801 aaggtcatta cctcccccat attcacaaac gcaggttgat cggcgtagcg cgcgaccgac
     7861 tgctcaaaca tatctaccag agattgataa cggtcagggt tgatctccgt cggaacgtcc
     7921 gcgggataac ggttaagcca aaccttcttc aattcttcac ctctaaaatg cgtgttcgtc
     7981 gtcatcgcaa ccccaaatga tatacatgcc attaacataa tattaactca tcataccagc
     8041 ttgataatta cccaacgaaa aggttgcgaa gcgcgtcact atttattttt atctttaccg
     8101 taagaatgca gaaacagcgg accagccgct gtttctgcat tctttaaaaa caagcaatta
     8161 ttcagttaca actgtttgta ctctcgcggg gccgggatta taccagcccc atccgccgta
     8221 gccatagggc cagccacgac cgccataaaa ccatggatca atcggctgag gcggcataat
     8281 cacctgctgg gttaaatgcc aacgtttgta acccgttact tgcatcacca taaatttata
     8341 gggcgtattg ccgattttgc cgtcaaccgc accagtgatt ggcccgacta ccgtaaccag
     8401 ttgtccacgg aaatccaccg ggtccagaaa accgttcaca tcggcataaa tgcgaccgcg
     8461 agaaggttct cccagcgtcg gtctggctcc gctgtccagc ggtacggtag caatttccag
     8521 gcgagttttc ccttgctggt tttgtaccgc aaccactttg ccaccaaagc gtgcctcctg
     8581 accaacgtac agctgcggcg cactcatcac ccgaactaaa tcttgttgcg gcgtgggact
     8641 gctgccttta atggcgtccg gcacagtgac acaaccgctc agcattagcg caaacgtacc
     8701 tgccagtatg cctttgataa cattcttttg aaccgccatg gtgcgactcc tttttttctc
     8761 agggcatact cttaagattc attctttgcc cggaagtttc ttccatgcga cgttgttacg
     8821 taaataaacc ggttcggcat gttccaccgc caccgtttta ccctcagcaa acatctgaca
     8881 cgcaatcggc agcatatctt cagcagcagg cagtaacact tcgccatcgc gcaaaaccag
     8941 cccgctctct ttaccgagat ccggccaagc ttgccagccc gtccctaccg tcacccattc
     9001 gccggaaagc tgttgcattc gttcatggac gatttcgggt ttgagtacgg cttcggtttc
     9061 ttcaccgtgc cagataccgt tttcatcacg ctgatattcg gcccagtaaa cttcgcccat
     9121 tcgcgcgtca atggctgcca gcacgcgggt tgcgccgttt ttgcgccacg ccccttgcgc
     9181 catcgtcatt agcgtggaga cgccaatcat cggtaattcc gcgccaagcg ccagcccttg
     9241 cgcgatgcca ataccaatgc gcacgccagt aaagctaccg gggccgcgcc cgtaagccag
     9301 agcgttaata tcagtcaggg aagttccgct ggtggtcagg atatcctgca ccatcggtaa
     9361 gattcgttga gtatgttcac gagggcaaag ctcaaaatga gcgttgacag taccgtcgtt
     9421 ccacagggcg acagagcagg cctctgtcgc ggtatcgata gccagaattc gcatgggtct
     9481 tcgtgcttag atcaataaaa aggcgcgcat cataccatac tccgtaacaa attacctgga
     9541 ggatggtatc gcaaggaaac gaaccgcacg ggcaatgtca cgggtgcgtg gcgcgggcgg
     9601 cagactggcg agaaacgtcg cgccgtaagg acgcatcacc agccgattgt cacaaatcac
     9661 cagcacgcca cgatcgtcgg cgtcgcgaat cagtcgccct accccctgtt tgagagtaat
     9721 gacggcatct ggtagttgca cttcatcgaa cgggtcgcca ccgcgcaaac gacaatcttc
     9781 catgcgcgct tttaacagtg gatcatccgg cgaggtaaac ggcaatttgt cgataattac
     9841 caatgacaat gtatcgccac gcacgtccac cccttcccag aaactgctgg ttgccacaag
     9901 aagcgcatta ccggcgctga caaattgctg caacagttgc cctttgctgg tttccccctg
     9961 caacaataca ggaagcgtca tggtagcgcg gaactgctcg gccagatcgc gcatcatggc
    10021 gtgcgaggta caaagcataa aacaacgacc gttgttagct tcgatgatcg gtcgcagcat
    10081 tgccgctaac tggcgagcag aacctggctg gttggtttgc ggcagattgc gcggcacaca
    10141 gagtaacgcc tggcggctgt aatcaaatgg gctgggcaac agcaacgact cggcctgttc
    10201 gatgccaagc cgcgaggtga aatgatgcag atcgtcgttc accgacagcg ttgctgaggt
    10261 gaagatccag ctaccgggtt tttgcgccat taactctttg aatttatccg ccacgctgag
    10321 cggcgtgaga gccagagtaa aatggcgcga agtgcattcg taccagtagc tgtagcccgg
    10381 ctgattgatc tcttttagcc gcttcagccg tgtgcgatac aacgtggcgc gctcaaatgc
    10441 cgcatccagc aaggcggaac gccccagtga cagtttcgcc acgtcataac aaagttccag
    10501 ggtgtcatcg agcagtaaaa atgcccgctg aatttgcgga ttagctaaca gctcacgcag
    10561 gttaccgcga taacctggct caccgagttg cagacgaaaa tcctgcgcac tctgggcaag
    10621 acgatcagcg cacttttgta actgctgggt gtcttttaat tcggtgcggt aggcgatggt
    10681 gatgtctttt gccaggtcga gcagttgtcg actggagagt gactgaccaa aatactggct
    10741 ggcaatgtcc ggtagctggt gggcttcgtc gaagatcatg acgtccgctt ccgggatcag
    10801 ttcgccaaat ccactctctt taaccaccat atccgccaga aagagatgat ggtttaccac
    10861 caccacatcg gcgtccatcg cttttttacg tgctttgacc acaaagcaat ctttatacat
    10921 cgggcagtcg ctgccaagac agttgtcgtt ggtgctggtg accagcggcc acgcctgtga
    10981 atcttccgcc acgctgacgc aggtgctgat atcaccatcg actgtttgat tagaccagga
    11041 gcgcagcagg atcacatcgc ttaagatttg taccggcaga tcgccccccg ccagcgcctg
    11101 ctgttcgaga cgttcgaggc agaggtagtt tgagcgccct ttcagcagcg ccacgttgcc
    11161 cgtatatttc aatgcctttg agactgttgg caaatcgcgg ctgtagagct gatcctgcaa
    11221 cgcttttgag ccggtcgaga taatgacttt ctttttcgcc cgcagcgcag gagccaggta
    11281 agcgtaggtt ttgcccgtac cggttcctgc ttccaccacc agcggctggc ctttttctat
    11341 cgcctgggtg acggctaccg ccatctgtcg ctgtggttct cgcggcttaa agcctggtat
    11401 cgctttcgcc agctgaccgt ctggtgcaaa atcgtccgtc acactacccc ctgttgattt
    11461 gaacagggat tatgtcagga tgagggcgct ttcgccagtt gaagtggtga cggcgacctc
    11521 acattgtggc agtctttgca gcacgaaaat ggaagtataa tgaggacaaa atgatgacta
    11581 tcgttcgtat cgatgctgaa gcccgctggt ctgatgtagt aatccacaac aacacgctct
    11641 actacactgg tgtaccggaa aacctcgacg ccgatgcctt tgagcaaacc gccaacacgc
    11701 tggcacagat tgacgccgtg ctggaaaaac agggcagcaa taaatcgagc attctggatg
    11761 ccaccatttt cctggccgat aaaaacgact tcgcggcgat gaataaagcg tgggatgcct
    11821 gggttgtcgc gggtcatgcg ccggtgcgct gcacggtaca agcgggtttg atgaacccga
    11881 agtataaagt tgaaattaag attgtggctg cggtgtaagc tttatcgaag caaaataagt
    11941 cagacgataa tttatcgata atactggtcg gttttacata aatcgaccag agaataagat
    12001 attactgttg atgcttctgc taattcatta tttatattta taatttcaat tttatctata
    12061 aaactaacta tataaataaa cataaacatg ccgttgtgtt cgccctttga ttagcaactc
    12121 tggttttctt tcttagctga acaatctggt tatagcgtgc ggactgaccg ttaaatttct
    12181 ccatcttact ggataacaca ccatgagctg ctacctttaa aacacctgaa tgtcaacagg
    12241 ttaactcgtg ccatatcgtt ataatccctt tgatattaga tgcaaattaa ggtcatatat
    12301 agccttatcg ataacatggt taattttaag gataagaata tgcctgctgt aatagataaa
    12361 gccctggatt tcattggtgc catggatgta tcagcgccaa caccaagttc gatgaatgaa
    12421 agcacggcga agggaatctt taaatattta aaagaactgg gagtacccgc gagtgccgct
    12481 gatattacgg cgcgagctga ccaggaaggc tggaaccctg ggttcacgga aaaaatggtt
    12541 ggatgggcaa aaaaaatgga gacaggtgaa cgttctgtga ttaaaaatcc tgaatacttt
    12601 tcaacatata tgcaggaaga actaaaagca ctggtctgag ttaaatttat atcagcataa
    12661 atgggtcagg acgcttttaa tcacatataa aaagcgtcct ttttctcaca atcaaatgat
    12721 catcggcttc tataacgaaa tcgatacgga ttagtgtgtt actcgtcttc atcctcaaaa
    12781 cgcgccacga ttcgctcgcc ggagtggttg gcacgcagct cttctgccac cagcgcgatt
    12841 gcctggccgc tgctcatccc ttgtgccatc agttcctgga tccgctcgac agctttttgc
    12901 tgctgttcat gggtgagtga aggtaaacct gcaaacattg ttaactcctg ctaaattgtt
    12961 ggcgctaatt atttcatgct acccggcaca tagccagtag agtcaggact gatgaagacg
    13021 ttatctcccg ctgtgattac tttaccctgg cgtcaggacg ccgctgaatt ttatttctcc
    13081 cgcttaagcc acctgccgtg ggcgatgctt ttacactccg gctatgccga tcatccgtat
    13141 agccgctttg atattgtggt cgccgagccg atttgcactt taaccacttt cggtaaagaa
    13201 accgttgtta gtgaaagcga aaaacgcaca acgaccactg atgacccgct acaggtgctc
    13261 cagcaggtgc tggatcgcgc agacattcgc ccaacgcata acgaagattt gccatttcag
    13321 ggcggcgcac tggggttgtt tggctacgat ctgggccgcc gttttgagtc actgccagaa
    13381 attgcggaac aagatatcgt tctgccggat atggcagtgg gtatctacga ttgggcgctc
    13441 attgtcgacc accagcgtca tacagtttct ttgctgagtc ataatgatgt caatgcccgt
    13501 cgggcctggc tggaaagcca gcaattctcg ccgcaggaag atttcacgct cacttccgac
    13561 tggcaatcca atatgacccg cgagcagtac ggcgaaaaat ttcgccaggt acaggaatat
    13621 ctgcacagcg gtgattgcta tcaggtgaat ctcgcccaac gttttcatgc gacctattct
    13681 ggcgatgaat ggcaggcatt ccttcagctt aatcaggcca accgcgcgcc atttagcgct
    13741 tttttacgtc ttgaacaggg tgcaatttta agcctttcgc cagagcggtt tattctttgt
    13801 gataatagtg aaatccagac ccgcccgatt aaaggcacgc taccacgcct gcccgatcct
    13861 caggaagata gcaaacaagc agtaaaactg gcgaactcag cgaaagatcg tgccgaaaat
    13921 ctgatgattg tcgatttaat gcgtaatgat atcggtcgtg ttgccgtagc aggttcggta
    13981 aaagtaccag agctgttcgt ggtggaaccc ttccctgccg tgcatcatct ggtcagcacc
    14041 ataacggcgc aactaccaga acagttacac gccagcgatc tgctgcgcgc agcttttcct
    14101 ggtggctcaa taaccggggc tccgaaagta cgggctatgg aaattatcga cgaactggaa
    14161 ccgcagcgac gcaatgcctg gtgcggcagc attggctatt tgagcttttg cggcaacatg
    14221 gataccagta ttactatccg cacgctgact gccattaacg gacaaatttt ctgctctgcg
    14281 ggcggtggaa ttgtcgccga tagccaggaa gaagcggaat atcaggaaac ttttgataaa
    14341 gttaatcgta tcctgaagca actggagaag taagacgtgg aataccgtag cctgacgctt
    14401 gatgattttt tatcgcgctt tcaacttttg cgcccgcaaa ttaaccggga aaccctaaat
    14461 catcgtcagg ctgctgtgtt aatccccatc gtccgtcgac cgcaaccggg gttgttgctg
    14521 actcagcgtt cgattcatct gcgtaaacac gctggacaag tggcattccc tggaggtgca
    14581 gtcgatgaca cggacgcatc agctatcgcc gccgcgctgc gcgaagctga agaagaggtc
    14641 gctataccgc cttccgccgt tgaagttatc ggcgtgctgc cgcccgtcga tagcgtcact
    14701 ggctaccagg taaccccagt ggtcggcatt atcccgcccg atctgccgta tcgcgccagt
    14761 gaagatgaag tctcggcggt gtttgaaatg ccgctcgccc aggcattaca tctgggtcgt
    14821 tatcaccctt tagatatcta ccgccgtggt gattcacatc gggtatggct gtcctggtac
    14881 gaacagtatt ttgtatgggg aatgaccgca ggcataattc gtgagctggc gctgcaaatt
    14941 ggtgtgaaac cctgactata cttatcttta catctacaaa acactacttg agacaatcat
    15001 cgcaatatta gttaaatcgc ggtttttgat tagtttaatt catgtgaata gttaagccag
    15061 tcgccgcgtt ccctcttaca ctatgcgctg ttattagttc gttactggaa gtccagtcac
    15121 cttgtcagga gtattatcgt gattagtcta ttcgacatgt ttaaggtggg gattggtccc
    15181 tcatcttccc ataccgtagg gcctatgaag gcaggtaaac agttcgtcga tgatctggtc
    15241 gaaaaaggct tactggatag cgttactcgc gttgccgtgg acgtttatgg ttcactgtcg
    15301 ctgacgggta aaggccacca caccgatatc gccattatta tgggtcttgc aggtaacgaa
    15361 cctgccaccg tggatatcga cagtattccc ggttttattc gcgacgtaga agagcgcgaa
    15421 cgtctgctgc tggcacaggg acggcatgaa gtggatttcc cgcgcgacaa cgggatgcgt
    15481 tttcataacg gcaacctgcc gctgcatgaa aacggtatgc aaatccacgc ctataacggc
    15541 gatgaagtcg tctacagcaa aacttattat tccatcggcg gcggttttat cgtcgatgaa
    15601 gaacactttg gtcaggatgc tgccaacgaa gtaagcgtgc cgtatccgtt caaatctgcc
    15661 accgaactgc tcgcgtactg taatgaaacc ggctattcgc tgtctggtct cgctatgcag
    15721 aacgaactgg cgctgcacag caagaaagag atcgacgagt atttcgcgca tgtctggcaa
    15781 accatgcagg catgtatcga tcgcgggatg aacaccgaag gtgtactgcc aggcccgctg
    15841 cgcgtgccac gtcgtgcgtc tgccctgcgc cggatgctgg tttccagcga taaactgtct
    15901 aacgatccga tgaatgtcat tgactgggta aacatgtttg cgctggcagt taacgaagaa
    15961 aacgccgccg gtggtcgtgt ggtaactgcg ccaaccaacg gtgcctgcgg tatcgttccg
    16021 gcagtgctgg cttactatga ccactttatt gaatcggtca gcccggacat ctatacccgt
    16081 tactttatgg cagcgggcgc gattggtgca ttgtataaaa tgaacgcctc tatttccggt
    16141 gcggaagttg gttgccaggg cgaagtgggt gttgcctgtt caatggctgc tgcgggtctt
    16201 gcagaactgc tgggcggtag cccggaacag gtttgcgtgg cggcggaaat tggcatggaa
    16261 cacaaccttg gtttaacctg cgacccggtt gcagggcagg ttcaggtgcc gtgcattgag
    16321 cgtaatgcca ttgcctctgt gaaggcgatt aacgccgcgc ggatggctct gcgccgcacc
    16381 agtgcaccgc gcgtctcgct ggataaggtc atcgaaacga tgtacgaaac cggtaaggac
    16441 atgaacgcca aataccgcga aacctcacgc ggtggtctgg caatcaaagt ccagtgtgac
    16501 taatacttct tactcgccca tctgcaacgg atgggcgaat ttatacccgc tttctcgtct
    16561 gctgtaatat tccccactac acttccactg ttgcgtcagg cgtttgtcgc catacgctta
    16621 cagggtggcc cgcatgcaaa aagcacaacg gatcattaaa acctatcgtc gtaatcgaat
    16681 gattgtttgt acgatttgcg cactcgttac gctcgcttcg accctgagcg tgcgatttat
    16741 ttcacagcgt aacttaaatc aacaacgggt agtacaattc gccaatcacg ctgtagagga
    16801 attagataaa gtactgcttc ccctacaggc aggtagcgaa gtcttgcttc cgctgattgg
    16861 tctgccctgc tctgtcgccc atttgccatt acgtaaacag gcggcaaaac tccaaactgt
    16921 gcgatccatt ggcctggtgc aagacggcac actttattgc tccagcattt ttggttatcg
    16981 caatgtgccc gtcgtggaca ttctggctga acttcctgca ccgcaaccac ttttacgcct
    17041 gacgatcgac cgtgccctga ttaaaggcag tccggttttg attcaatgga cgcctgcagc
    17101 gggcagtagc aatgctgggg tcatggagat gattaacatc gacttactga cggcaatgct
    17161 gcttgagcca caactgccgc aaatcagtag cgccagcctg acggtggaca aacggcattt
    17221 gctctatggt aatgggctgg tagattccct tccgcaacct gaagacaatg aaaactatca
    17281 ggtttcttcg caacgctttc cttttaccat taacgttaat ggtccggggg ctacggcgct
    17341 ggcatggcac tatcttccaa cacaattacc gctggcggtg ctgctaagtt tactggtggg
    17401 ctacatcgcc tggctggcga ccgcttaccg aatgagcttt tcccgcgaaa tcaatctggg
    17461 cctggcgcaa catgagttcg aattgttctg tcagcctttg cttaatgcgc gcagccagca
    17521 atgtattggt gtagagattt tgctgcgctg gaacaatccg cgtcagggct ggatttcacc
    17581 ggatgtgttt attcctatcg cggaagaaca tcatttaatt gtgccactga cccgctatgt
    17641 gatggcagaa accattcgtc agcgccatgt tttcccgatg agtagtcagt ttcatgttgg
    17701 cattaacgtc gcacccagcc attttcgccg tggtgtgctg ataaaagatc tcaatcagta
    17761 ctggtttagc gctcacccga ttcagcaact gatcctcgaa atcaccgaac gcgatgcctt
    17821 actggatgtt gattatcgga ttgcccgcga gctgcatcgt aaaaacgtca aactggcgat
    17881 tgatgacttc ggcaccggca acagctcgtt ttcctggctt gaaacattac gtcctgacgt
    17941 gctgaaaatt gataagtcat ttaccgcagc tataggttct gacgcggtta actcgacggt
    18001 gaccgatatc atcatcgcgc tggggcaaag actgaatat
//
LOCUS       DACAOP010000091        17744 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.091, whole genome shotgun sequence.
ACCESSION   DACAOP010000091 DACAOP010000000
VERSION     DACAOP010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17744
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.091"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..551
                     /locus_tag="IT892_003457"
     CDS             <1..551
                     /locus_tag="IT892_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP3136638.1"
                     /translation="TNSSHNLPVAPNLLNQTFAPTVPNQVWVADLTYVATQEGWLYLA
                     GIKDVYTCEIVGYAMGERMTKELTGKAMFMALRSQRPPAGLIHHSDRGSQYCAYDYRV
                     IQEQFGLKTSMSRKGNCYDNAPMESFWGTLKNESLSHYRFNSRDEAISVIREYIEIFY
                     NRQRRHSRLGNISPAAFREKYH"
     gene            complement(1107..2132)
                     /locus_tag="IT892_003458"
     CDS             complement(1107..2132)
                     /locus_tag="IT892_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP3136639.1"
                     /translation="MKVKAVYINKPGEIATRLVDYPVRKDNEVLIKVDAAGICGSDIG
                     AFRGTNPLVTYPRIIGHEVTGIVLETGEGVPQNIKQGDRVIVDPYVYCGHCYPCSVGR
                     TNCCENLKVIGVHIDGAMQEVVSHPAHLIHKIPDNVPSEMAPLAEPLTIALHALHRAQ
                     LKAGEHVVIIGAGAIGLMAALSSLNYKATPILVDIVDERLQYAKSLGVPYVVNSAKAN
                     VIEAVKDITQGTMAQVVVEASGANSAIRSTLDLASFAGRIAYTGWPKQETSLPTNLIT
                     FKELDLRGSRTSAGEFEEALQMLSTLNINPADIVSKVVTIDEVPEAVKELDQFPERYL
                     KINVKFI"
     gene            complement(2104..3393)
                     /locus_tag="IT892_003459"
     CDS             complement(2104..3393)
                     /locus_tag="IT892_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136640.1"
                     /translation="MKRKTMGWIIVFLLFIVYMLNYMDRSALSITAPLIEKELGFNAA
                     EMGMIFSAFFVGYALFNFIGGWASDKVGPKTVFLVAALLWSVFCGMTGLVTGLWTMLA
                     VRVLFGMAEGPVSAAGNKIINNWISRKESATAIGIFSAGSPLGGAISGPVVGLLAISL
                     GWRPAFGIIFIFGLVWVLLWYFFVSDKPSKSKRLAAEERVDFENHDDIILAEDGKGTP
                     SLGYYMKQPMVWATTLAFFSYNYILFFFLTWFPSYLNHSLHIDIKEISIATVIPWFIG
                     AIGMVLGGVCSDFIYRITGNALLSRRLILGSCLAGAAVCVAVSGTVTSIGSAITLMSV
                     SLFLLYLTGPIYWAVIQDVVHKDKVGSVGGAMHGLANISGIIGPLVTGFIVQFSGKYD
                     YAFYLAGAIAIISSLLVFIFVKNKGLKVNESQSCVHQ"
     gene            3673..3976
                     /locus_tag="IT892_003460"
                     /pseudo
     CDS             3673..3976
                     /locus_tag="IT892_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610815.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(4139..4447)
                     /locus_tag="IT892_003461"
                     /pseudo
     CDS             complement(4139..4447)
                     /locus_tag="IT892_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(4627..4917)
                     /locus_tag="IT892_003462"
     CDS             complement(4627..4917)
                     /locus_tag="IT892_003462"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136641.1"
                     /translation="MIRKIAEGHISRVSGKVMSAVIRECEDFPPTTVKDIIELLEFYD
                     ETASRVLAGHHRQIPTNNPLLKPWVFGVRFYAYNHFNAKLVTICDLPPTCLF"
     gene            5668..7977
                     /locus_tag="IT892_003463"
     CDS             5668..7977
                     /locus_tag="IT892_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009113451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP3136642.1"
                     /translation="MELWIFIVAIYLIYILFFKKKKTKSAGSYTSAPVKAPPKEWLAN
                     NKKNQSVMHNEDSEDDNLATFTLSGGRNAEYSITATQRQNFSKTTGALARWILPGEVI
                     TVGGVEVTGGYFYLGQRMNPVGHNSGGYYDDSSEASLIDDTLKIYPTSYIYEDSSLGY
                     WPSYSSLSPEARGAYLSWLTSDRCDTSCPIGYVFIYLYGLERRALVDSRDSNISDDEF
                     YSLFKEICRLRSVFNENRSFRNYSSQLLEAMSILRPNENLAAALSDDSEFSNSMQFRL
                     ILAKTVDAGAPVPADLALTWVTNHTEYSLRTPARRCAKEFAALFKRRYTLKYGEGMVV
                     KPNKARLRLDYTPASPSLRGIRLPVPDLPDPSALKGPVQKLMTLADICTDELDAYSRY
                     LGRKGTSANDTAAILLLPSEIVNESADKILSAFKRWADDAILSKGGVVSVADFWSHMN
                     ATCPAKINKKEADLMQAFAQKMGYCLAPDPYYHHVKADVNGVLVLFPAGESGRFSPSP
                     EFITAVLTLRLGSVVALIDNSFDQAEQKVLENAINNNVSFSDDEKRSLHAYLTWQLHT
                     PANMTGMKSRIELLGAAEKSAVGKVIVSVACSDGRITPAEIKQLEKIYTSLGLDPSSV
                     SSNIHQHSVTETALVSSVPANQSTAGFTLDANVLARHESATDDVRKLLNSIFTEEEPE
                     QPESAPASLTGEGGLDSAHSQLYRRLLEKEQWSRKEATELCSNWNLMLGGALEVINDW
                     SYAVVDAPVLEDADDHIWVDLEIAKELEG"
     gene            7981..9297
                     /locus_tag="IT892_003464"
     CDS             7981..9297
                     /locus_tag="IT892_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000117530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP3136643.1"
                     /translation="MSVTRIRVKERDAIIQSLKSGVTPRIGIQHIQVGRVNEITALHQ
                     DIERIADGGASFRLIIGEYGSGKTFFLSVVRSIALEKKLVTVSADLSPDRRIHSSGGQ
                     ARNLYSELMKNMSTRNKPDGNALLSVVERFVTEARKEADANGSQVSSVIHKRLAALSD
                     MVGGYDFAKVIDAFWRGHEQDNETLKSNAIRWLRGEYTTKTDARNDLDVRTIISDASF
                     YDSLKLMSLFVRQAGYAGLLVSLDEMVNLFKLNNTQARTANYEQILRILNDCLQGSAE
                     NIGFILGGTPEFLFDPRKGLYSYEALQSRLAENRFAQKAGVIDYSSPTLHLASLTPEE
                     LYILLKNLRHVYAGGDPANYLVPDEALTGFLHHCSKTIGDAYFRTPRNTIKGFLDMLA
                     VLEQNRTMNWQALIEGVAIEEDKPSDMGDAIVEESDDDDGLANFRL"
     gene            9294..11492
                     /locus_tag="IT892_003465"
     CDS             9294..11492
                     /locus_tag="IT892_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010434172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP3136644.1"
                     /translation="MSSAYNSLDPRVRKWIYKQGWSSLRPLQESSIPAILARDRDVLI
                     SAGTAAGKTEAFFLPACSAIADLTGGFGIIYICPLKALINDQHRRLESLGEALEMQVT
                     PWHGDVPQSKKKKARTSPSGILLITPESLESLLINSLGWLKQAFSSVAYIVIDEFHAF
                     IGSERGIQLLSLLNRIDHVLGRQLNPVPRVALSATLGELEKVPELLRPDKRLPCETVT
                     DSNSTATLQVQVKGYLERVPEKGEELQSSAEQLVCADIFRLCRGDSHLVFANSRKRTE
                     SIAAILSDMCEANVVPNEFFPHHGSLARELREALEVRLQKGNLPTTAVCTMTLELGID
                     IGKVQSVIQVTPPHSVSSLRQRMGRSGRRDSPSVLRMLITEPELTATSSIVDHLRLQL
                     VQAMAMIRLMISKRWFEPADIRQKHYSTLLHQILAITAQWGGVRADQLWSQLCQTGPF
                     RNVDINDFKSLLKHMGTCGLLSQLASGEIVVGAEGEKLTNHYTFYAVFNTPEEFRIVT
                     GNRTLGTVPVDSPLLPEQHIIFGGRRWKVTEIEVEKKVIYVEATKGGQPPLFSGSGMS
                     VHDVVRQEMLAIYRENDYRIAVGNKRVDYADAAARSLFAEGSDNFQRYNLHNDCFIAS
                     GQNCYVIPWMGDKIVNTITSLLIRCGFKASSFAGVIEVEDSGVASVQRVLKKMLLSGL
                     PSEFELAAVVPDKYLDKYDEYLPETLLAKGYGAQAYDIEGTCTWLQKHLQ"
     gene            11974..12990
                     /locus_tag="IT892_003466"
     CDS             11974..12990
                     /locus_tag="IT892_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136645.1"
                     /translation="MSSVRTDKFIRYGFAVVAIVAILITTITTPNPTPYQYIVYRIVL
                     ALAAGCIGAVLPGFLEVKFNGWLRASGAVAIFAIVFFISPDLLQQNPESASKPVPPTV
                     IDAYAVNTSNRDRYLELFRTGQFGQRDKLRIGCVEWSESSCVAAGNFLRLLSEAGWEI
                     DSDAVFRMQPSVPVEGVSIVSRGDDLVGLPKVPPHMGRWSRSDISYEILTAAFKLMGV
                     PVYFSSDPTLQPGTTGVYFGPKPKLDAPVMQKDENVRRELLRYVGLGMTIQRACSQQP
                     VELCGGEIFSWETSVSSFLRQQRFNSDAVNRWLALPQVNAASATADMKIKLDLLMSFV
                     LGIE"
     gene            13634..15994
                     /locus_tag="IT892_003467"
     CDS             13634..15994
                     /locus_tag="IT892_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HAP3136646.1"
                     /translation="MKSMQSKTGSPLVRTEAELESRLTSALNIAFPNIPREDLIEQRH
                     FTVRLGHGTYKIDSAAHWKKYGRADVLIFHRERPLAVIELKREDLTLTHDDYEQAQSY
                     ANQLTPRPPLVVVTNGKDTRVYDSSNGQQWSGGQDASAAVNKMLANSAKLAAADMRWA
                     IEALMGRETNAWVPAVREETARLLIDITDQPGHSEHPFANNLLFPRKITSLVIESAVM
                     GTAFTIIEGDAQSGKSSCLREISLKTESSDLLAVLMLRGSGPGLFQALANLFAAEFEW
                     NLTSNDARNWLRRMSNCTEGPSLMLAIDDVEPGSQMATDLEELAGIRFGNRLVVVLTT
                     YHANALLKNPNGRTPSAIGSRSKVFKTSPMSLDEFKLAQQILSDQRIVFQQGAEYADD
                     YRSPWVLRTIYDDIVRNHQYQKTDLIAYLPPSPGMELIDAAQKSYESQYDLLRYYRVL
                     ARCALADTNSHSVELMFAKANGFVVRYDALSDEARGVVNELKHMGAVRIFRLSGWEDV
                     VVPTVPAAYLLELSDAVCDELVLRAEQDPQDAGAWLGERLDATYLGDMIGAQAIRRMA
                     AKERYFSFGIIQGLLSIEPYKEPIKNGLFTLAMPDNQQVNLKIEDGLAWISKHGDDAK
                     SVLVNLEDQIPKVISKSTSWMILGQLAKLPSAEVGDDDQRIDAYILLSIGRCPFPLIR
                     TNIEGLPYFEHNFGDQGDVLCLEKASIEVATQAMADLFSAPWLYADQWVDTAIATGSI
                     HLLHRLFAALNTVILRRIPVQSDWANEALNQRVSPALKEAIRSLSS"
     gene            16171..16470
                     /locus_tag="IT892_003468"
     CDS             16171..16470
                     /locus_tag="IT892_003468"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP3136647.1"
                     /translation="MTKPVSISKKPREQHSPEFRNEALKLAERIGVAAAARELSLYES
                     QLYAWRSKQQQQMSSSERESELAAENVRLKRQLAEQAEELAILQKAATYFANRLK"
     gene            16467..17310
                     /locus_tag="IT892_003469"
                     /pseudo
     CDS             16467..17310
                     /locus_tag="IT892_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707076.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(17307..17462)
                     /locus_tag="IT892_003470"
     CDS             complement(17307..17462)
                     /locus_tag="IT892_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000160236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136648.1"
                     /translation="MTKGNISERDFDILIKLSGIHSEKAILALKKYYVDGVIRKIDPT
                     HVMWTRP"
BASE COUNT         4723 a         4015 c         4265 g         4741 t
ORIGIN      
        1 ctacgaactc gagccacaat ctgccagttg cgccaaatct gctgaaccag acgttcgctc
       61 ctacagtacc aaatcaggtc tgggtggcgg acctgacgta tgttgccaca caggagggat
      121 ggttgtacct cgctgggatc aaagatgttt atacgtgcga aattgtcggc tacgccatgg
      181 gagagcgcat gacaaaagag ctgacaggta aagccatgtt tatggcgctc aggagccagc
      241 gcccacctgc cgggctaatc caccactccg atcgaggttc acagtactgc gcatacgatt
      301 accgggtcat ccaggagcag tttggtctga aaacatcaat gtcgcgtaaa ggtaactgtt
      361 acgacaacgc tccgatggaa agcttctggg gaacgctgaa aaatgagagc ctgagccact
      421 atcgttttaa tagccgggat gaggccatct cagtaatacg ggaatacatt gagattttct
      481 acaatcgtca gcgtcgtcac tctcgtctgg ggaatatctc cccggcagcc ttcagggaaa
      541 aatatcatta gatggctgct taaaaaaaga acaaatggta gtgtccgcta ttgccagtac
      601 acctcaggat gccgtccgtc tcttctgccg ctggccgcag ttgcctgcgt ttatgcttca
      661 ttaatcatca tcgggttcgg atgtcctaat cacggttaat tatgttcggc ccttcatgct
      721 gccggttttg cagcgctact acggcgtcgg tagcacactg gcagagcggc agatctcccg
      781 gggtaattcg cacgactttc ctgcttatgc ctgtcggctg tacgtcaccg cgttccgtgt
      841 gagtattggg ctttggtgat ttgtgccgcc ttagccgctt cctgttcgtc aggccagcat
      901 tttgcatccg gcttccttca gatttcacct cgcgatgaac atccttgcct tccgctaaca
      961 cttcccctca ccgggtgttt ggagaacttt cacctcttag tcgttcttca gccaccacag
     1021 ttgaagaaca gcgccagtca cggcgcacac aaaaaacgcg tagtgaacac actacgcgtc
     1081 agacttttta tttttgttaa ttataattaa atgaatttca cgttaatttt cagatagcgt
     1141 tccggaaatt gatctaactc ttttacagcc tcaggaactt catctattgt cacgactttg
     1201 ctcacgatat cagccggatt aatattcagc gttgataaca tttgcagggc ttcttcaaat
     1261 tcaccggcac tggtacggga accacgtaaa tctagttctt taaaggtaat tagattagtt
     1321 ggtaacgatg tttcctgctt tggccaacca gtataggcta tacgccctgc aaatgaggcc
     1381 agatccaggg tacttctgat tgcgctattt gcaccagagg cttccaccac aacctgagcc
     1441 atcgtccctt gtgtaatatc tttcactgcc tcaataacat tagcttttgc ggagtttact
     1501 acataaggta cgccgagcga tttcgcgtat tgcaaccgtt catcgacaat atcaaccaga
     1561 atgggagttg ctttatagtt caacgaactc agggccgcca taagtccaat agcgcctgca
     1621 ccaataatga cgacatgttc acctgctttc aattgcgctc gatgtaatgc gtgtagggca
     1681 atagttaagg gttcagccag tggcgccatc tctgacggta cattgtcagg aattttgtga
     1741 attaagtgag ccggatgcga aaccacttct tgcatagcgc catcaatatg tacgccgatg
     1801 acttttaagt tctcgcagca attagttcta cctacagaac atggataaca gtgaccgcaa
     1861 taaacatagg gatctacaat aacccggtcg ccctgtttga tattttgtgg taccccctca
     1921 ccggtttcca gaacaatccc ggtgacttca tgtccaataa ttctcggata agttaccagt
     1981 gggttagtac cacgaaatgc accgatgtca gaaccacaaa ttcccgctgc atccacttta
     2041 attaaaactt cattatcttt tcttactgga taatcgacca gacgggtagc aatttcacca
     2101 ggtttattga tgtacacagc tttgactttc attgactttc aatcctttat ttttaacaaa
     2161 aatgaatacc agcagacttg aaatgattgc tatggcacct gcaagataga atgcgtaatc
     2221 atatttacca ctgaactgga caataaaacc ggttaccaat ggaccaataa tgccggaaat
     2281 atttgccaga ccgtgcatcg caccgcctac gctacctact ttatctttat gcactacatc
     2341 ctgaataaca gcccaataaa taggtccagt tagataaagc aggaataagg aaacagacat
     2401 cagcgtaatc gcactaccaa tagaggtaac agttccggaa acagcgacac aaaccgcggc
     2461 ccccgcaagg caactgccga gaattaaacg gcgagaaagt aaggcatttc ccgtaatacg
     2521 ataaataaag tcagagcaga cgccacctaa caccatgcca attgccccaa taaaccacgg
     2581 gataacagtt gcaatactaa tttctttaat atcaatgtgt aatgaatgat tcaaatagct
     2641 tggaaaccaa gtaagaaaga aaaatagaat atagttatag ctaaaaaatg ccagcgtggt
     2701 cgcccatacc atcggctgct tcatgtaata accaagcgaa ggtgtacctt taccatcttc
     2761 ggctagaata atatcgtcat ggttttcgaa atcgacacgt tcttccgctg ccagacgttt
     2821 actttttgac ggtttatcac tgacaaagaa gtaccacagt aatacccaaa ctaggccaaa
     2881 tataaatatg atcccaaacg ccggacgcca gccaagtgat attgccagca agccaacgac
     2941 cggaccagaa atagcgccgc caagtggtga accagcacta aaaataccga tagctgttgc
     3001 cgactcttta cgcgagatcc agttattaat aattttattt cctgctgcac taaccgggcc
     3061 ctctgccata ccaaataaaa cacgtacggc aagcattgtc cataatccgg tgaccagacc
     3121 ggtcatacca caaaaaacag accacaacag tgcagcaacc aaaaatactg ttttgggtcc
     3181 aactttgtca ctggcccaac cgccaatgaa gttaaataaa gcataaccaa cgaaaaatgc
     3241 gctgaaaatc atccccattt cagcagcatt aaagcctaac tctttttcga taagtggggc
     3301 cgtaatcgat aatgcagaac gatccatata gttcagcatg taaactataa acagaagaaa
     3361 aacgataatc caccccatgg tttttctttt catgatattt cctcttattg tggtctagtg
     3421 gcctgaccac aatatttaat atttattttt agatcatcat aaaaagaagg gttttgtgat
     3481 caatataaca aaaatgggat aaccagtgtt caataacaat tataatcact ctctagttgt
     3541 atgattttat ttactctatt ttgagtgatt aatatgtaag acagtatgac tttccgggag
     3601 agaggctctg atcaacgtgg tagctttaac gcgggttagc accaaggcca gtaccgcata
     3661 ggttagctgg cgctagccga tgtggctgac aaatgggagc ttcgtcagtt caaagaaacg
     3721 ccggaacagc gcttcgcgct ggagcaggaa catctgcagc cgttaccgga tacagacttc
     3781 gataccagtt acttcgacat ccgccatgtg tcctgggacc cgctataacg aagttggagg
     3841 taatcagtac agcgttcccg aaatgctgtg tggtcagcca gtctcgatac gaatatcgct
     3901 gaacgatgag ttgcggatct acagtaatga gaaactggtg gcctcacatc gcctctgctc
     3961 agtgtcgtct ggctagcaga tagtaccgga acctcacgcc ccgctctggc agcagatcag
     4021 tcaggtggaa catcgaccac tgagtgccta tgaggagctg ttgtgatgca tgtgtcaacg
     4081 acggatgaaa agtgatccac ttatatctcc accaacggcc caatattgat ccaccgtgtt
     4141 actcaggatt agcttctgct ataaccccgg cctttcgttt ctgtctgagt cgatagcttt
     4201 ctccttttat ctgaacgaca tgtgagtggt gtaagatacg gtccagcatc gctgaggtca
     4261 gggctgcatc accggcgaac gtttgatccc actgcccgaa cggcagattg gatgttagga
     4321 ttattgcgct tttttcgtaa cgtttagcga tgacctggaa gaacagcttt gcttcttcct
     4381 gactgaacgg cagatagcct atttcatcaa tgatgagcag gcggggggcc attactccac
     4441 gctgaagcgc ttacttaaaa tccgttgtta tgtatcacat ttttttcatt atggggtgct
     4501 gatatttcaa gagtaaatta tacccccaaa agtaacttga tacggggtga aggcggttgg
     4561 cctctggata caaagaaatc ctgatatata agggattaga gggggttttg ttgacgtcgg
     4621 gagagttcag aagaggcatg ttggcggaag atcacagatg gtgaccagct tggcattaaa
     4681 gtggttatag gcataaaagc gcacaccaaa tacccagggt ttcagcaagg gattattggt
     4741 cgggatctgc cggtggtgtc ctgctaatac ccggctggcc gtttcatcat aaaattcaag
     4801 cagttcaatg atgtctttaa ctgtcgtggg aggaaaatcc tcgcattcac gtattacagc
     4861 cgacatgact ttaccagata cccgggaaat atggccttca gcaatcttac gtatcaagct
     4921 ttccgtacat ggcggtcagg atgaatgaca ttttgcaatt ctgcgatata tggtgccaga
     4981 agctggctaa aaacacgctt ctcttcatga ctggcaaggc catagcacga catgtactta
     5041 tcagctaagc tgaccaaata ctgtgctgag ttccgaccag ttatggtagt tataacgtaa
     5101 tgccactgca tcccgggcgt agcttagatt gatattgagc gaccgtgaaa ggtatttggc
     5161 gtgggctttt gcttcagcgc atgtggggat ttgtttcatg gtttaagtct cttatctgtc
     5221 ctatgtgctc acgaaccata agaatcaaag acacttaacc aaaaaagatt tgataagtct
     5281 gcgctgcatt ccgctttggc cgtgagctgc cgggtcgcgc taaccttgtg cttaacgtat
     5341 tggaaagtag caccattgtc aacagagcca ttgaccctgc cgggctaaca gagaggttag
     5401 acatgaagcg aggtgcgatg ctggcaggca tcaggtgagg ggctgatacc acacttctgc
     5461 catggtttct gaattatcaa tgtccgcttt tgggcataga cgagattcat gctcggcagg
     5521 gaccgtagca agcgaaaagc ggaggttcgg gaaggttgtg atttgctttt aacctttgta
     5581 atttagaaat attattttaa gattaatcca cttcccatcg tcatcctttc ggtgttcgtg
     5641 aaaagctatt tttaaggtta ttgcctcatg gagttatgga tatttatagt agcgatttat
     5701 ttgatttata ttcttttttt caaaaagaag aaaactaagt ccgcgggctc ttatacttcc
     5761 gctcctgtga aagcaccacc taaagaatgg cttgctaata acaaaaaaaa tcagtctgta
     5821 atgcacaacg aggacagcga agatgacaat ctggctacgt ttacactaag tggcgggcgg
     5881 aatgccgaat acagtataac agccactcaa cgccagaatt tctcaaaaac taccggtgct
     5941 ttggctcgct ggattttacc gggggaggtg atcacagtcg gtggggtaga ggttaccggc
     6001 ggctacttct atcttggaca gcgaatgaac cctgtcgggc ataactcagg cggttattat
     6061 gatgatagta gcgaggcatc gctaattgac gacacgctca agatataccc cacatcttac
     6121 atctacgaag atagttcatt agggtattgg cccagttatt cctcactttc acctgaagca
     6181 cgtggcgcgt acctgagttg gcttaccagc gacagatgtg acacttcttg cccaattggt
     6241 tacgttttta tttatctgta tggtctggaa agacgggcgc ttgttgacag cagggacagc
     6301 aatatatctg acgatgagtt ctattctctt ttcaaagaga tctgccgtct cagatctgtt
     6361 ttcaatgaaa acagatcatt ccggaactac tcgtcccagt tacttgaagc gatgtccatt
     6421 cttcgtccga acgaaaatct tgcagcagct ctcagcgatg attcagagtt cagcaatagc
     6481 atgcagttca ggttaatcct ggcaaagact gttgatgcag gagccccggt tccagcggat
     6541 ctggctctga cgtgggtgac aaaccatact gaatactcat tacgaacccc cgcccgccgc
     6601 tgtgcgaaag aatttgctgc actatttaaa cggcgttaca cccttaaata cggtgaaggg
     6661 atggtagtga agccgaataa agcgcgtctg cgtttagatt acacgcctgc aagtcccagt
     6721 ttgagaggta ttcggcttcc tgttcctgac ttgcctgatc caagtgcatt gaaaggccct
     6781 gttcagaagc ttatgactct tgctgatata tgcacagatg aactggatgc ttacagtcgt
     6841 taccttggta gaaaaggcac ttcagcaaat gataccgctg caattttgtt gctgccttca
     6901 gaaatcgtta acgaaagcgc agataaaata ttaagtgcat tcaaacgctg ggctgatgac
     6961 gcgatcctca gtaagggggg agtagtttca gttgctgact tctggtcaca catgaatgct
     7021 acctgtccgg caaagatcaa caaaaaagag gccgacttga tgcaggcctt tgcacagaaa
     7081 atggggtact gcctggctcc tgacccctat taccaccacg taaaagcaga tgtcaatggt
     7141 gttcttgttt tattccctgc tggtgaaagt ggccgcttct ctccttctcc tgaatttatc
     7201 acagctgtat tgacgctccg attaggttcg gtagtcgcct tgattgacaa ttctttcgat
     7261 caagccgaac agaaagtgct tgagaatgcc atcaacaaca atgtcagctt cagcgatgat
     7321 gaaaagcgct ctctgcacgc atatttaacg tggcagcttc ataccccggc gaatatgacg
     7381 ggaatgaaaa gccggattga attactcggt gcagcggaaa aatcagctgt gggtaaggtt
     7441 atcgttagtg tcgcttgctc tgacggcaga attacgcctg ccgaaatcaa acagcttgag
     7501 aagatttata caagcctggg gttggatccc tcatccgtat caagcaatat ccatcagcat
     7561 tccgtaactg aaactgctct cgtttcatct gtaccagcta atcagtcgac ggcagggttt
     7621 acgctggatg ccaatgtact tgcccgccac gaatctgcca ctgatgatgt tcgtaaatta
     7681 ctgaactcga ttttcactga agaagaacca gaacaaccag aaagcgctcc agcctcatta
     7741 accggggaag gggggcttga ctccgctcat agccaacttt atcgcaggtt gctggagaaa
     7801 gaacaatggt ccagaaaaga ggcgacagag ttgtgtagta actggaacct gatgctcggc
     7861 ggtgcgcttg aggtgattaa cgattggtcc tatgcggtgg ttgatgcacc agtgctggaa
     7921 gatgctgatg atcacatttg ggttgacctg gaaatagcca aagaattaga gggttagtga
     7981 atgtctgtaa cacgtataag agtgaaagag cgcgacgcta ttattcagtc acttaagtcg
     8041 ggagtaacgc caaggatagg tattcagcat atccaggttg gccgcgtgaa tgagataacc
     8101 gccctccatc aggatattga acggattgct gatggcgggg caagcttcag acttatcatt
     8161 ggtgagtatg gttccggcaa aacgttcttt ttaagtgttg tacggtctat tgcgttagag
     8221 aaaaagctgg tcacggtcag tgcagacctt tctcccgaca gacgtattca ctcatcggga
     8281 ggtcaggctc gtaatctcta ctcagagctt atgaaaaata tgtccaccag aaacaaacca
     8341 gatggcaatg cattacttag cgttgtggaa aggtttgtta ctgaggcaag gaaggaagct
     8401 gatgcgaacg gctcccaggt ctcatccgtt attcataaac gccttgctgc tttgtcagat
     8461 atggtgggtg gatatgactt tgcgaaggtc attgacgcat tctggcgcgg gcatgagcag
     8521 gataacgaaa ccttaaaatc caatgctatt cgctggttgc ggggcgagta caccacaaaa
     8581 actgatgccc gtaatgatct tgacgtccga acgattatct cagacgcctc gttctatgac
     8641 tctttgaagt tgatgagcct ttttgtccgt caggcaggct atgccggact tttagttagc
     8701 ctcgacgaga tggtgaacct cttcaagttg aataatacgc aagcgagaac ggccaactac
     8761 gaacaaattt tgcggatcct gaatgactgc ctgcaaggct ccgccgaaaa tattggtttt
     8821 atcctcgggg ggacgccaga gtttcttttc gatccacgta aggggctcta cagctatgaa
     8881 gcgctccagt cgcgtctggc agaaaatcga ttcgcacaga aagctggcgt gattgactac
     8941 tcgtctccca cgctacatct tgccagcctc actcctgagg aactgtatat tttactgaaa
     9001 aatcttcgtc atgtttatgc tggtggagat cccgcaaatt atctggtgcc agatgaggct
     9061 ctgaccgggt ttctgcatca ctgcagcaaa accatcggag atgcttactt tcgaactccc
     9121 cgcaatacca taaaaggttt tctggatatg ctggctgtgc tggaacaaaa cagaacgatg
     9181 aactggcaag ctctcattga gggggtggcg attgaagaag acaagcccag cgatatgggg
     9241 gatgccattg tggaggaaag tgatgacgat gatggcctgg cgaatttcag actatgagca
     9301 gtgcctacaa tagtctcgat ccccgtgtcc gtaagtggat ttataagcag ggctggtcat
     9361 cattaaggcc cttgcaggag agctctattc cggcaatttt agcccgtgat cgtgatgtac
     9421 taattagtgc aggtacagct gcgggtaaaa cagaggcttt ctttcttcct gcctgttcag
     9481 cgattgcaga tctcactggt ggatttggca ttatctatat ctgtccgttg aaggcattga
     9541 ttaacgatca gcaccgtcgt cttgagagcc tgggggaagc cctggaaatg caagtgacgc
     9601 cctggcacgg ggatgtacca caaagcaaaa agaagaaagc acggacaagc ccgtcaggta
     9661 tcttacttat cacacctgaa tcacttgagt ctttgctcat aaactcattg ggttggctca
     9721 aacaggcgtt ttcttcagtg gcatacattg ttattgatga gttccacgct tttattggct
     9781 cagagcgtgg tatacaactg ctttcgctgc ttaatagaat tgaccatgtg ctgggacgcc
     9841 agttaaatcc agttccccgt gtcgcgttga gtgccactct gggagagctg gaaaaagtgc
     9901 cagaattatt gcgtccggat aagagattac cttgtgaaac ggtaacagac agtaatagca
     9961 ccgctacact acaagttcag gttaaaggtt atcttgagcg ggtgcccgaa aaaggggaag
    10021 agctccagag ctctgctgaa cagctcgtct gcgcggatat tttcaggctc tgtcgtggcg
    10081 attcccacct ggtctttgct aacagtcgaa agcgtactga aagcatagcg gcaatactga
    10141 gcgacatgtg tgaagcaaat gtcgttccta atgaattctt tcctcatcat ggctcccttg
    10201 ccagggagtt acgtgaggcg cttgaagtcc gactgcagaa agggaatttg cccacaaccg
    10261 ctgtttgtac aatgacgctg gagctgggta ttgatattgg taaggtgcag tctgtcatac
    10321 aagtgacacc tccgcattct gtttccagtc tgcgtcaacg catgggacgt tcagggcggc
    10381 gcgattcccc atcggtgctg agaatgttaa ttactgaacc tgaacttacc gcaaccagca
    10441 gcattgtgga tcatttacgg ctgcagttgg ttcaggcgat ggcaatgatc aggttgatga
    10501 tctctaagcg ctggttcgag cctgcagata tccggcagaa acattactcc acactactac
    10561 accagatcct ggctattact gcgcaatggg gaggtgttcg tgccgatcaa ctctggtcac
    10621 aactttgcca gacaggtccg ttccggaatg tggatataaa tgactttaaa agtctgctta
    10681 aacatatggg gacatgtggc ctgctcagtc aactagccag cggtgaaata gttgtcgggg
    10741 ctgaggggga gaagctgact aatcactaca cgttttatgc cgtattcaat acacctgagg
    10801 agtttcgcat tgtaacggga aaccgaactc ttggcacagt gcctgtagac tccccacttt
    10861 tgccggagca gcacatcatc ttcggcggac ggcgctggaa agtgacagag atcgaggttg
    10921 aaaaaaaggt tatctatgtt gaggcgacta aaggcggtca gccaccacta ttcagtggta
    10981 gcgggatgtc tgttcatgat gttgttcgcc aggagatgct cgctatctac agggaaaatg
    11041 attaccgtat cgcggtaggc aacaagagag tcgattatgc tgatgccgca gccagaagcc
    11101 tctttgcgga aggaagtgac aacttccaac gctacaatct acacaatgac tgttttattg
    11161 ccagtggtca gaactgctac gtgatcccgt ggatggggga taaaattgtc aatacaatta
    11221 cgtccctgct tatacgttgt ggctttaaag ccagttcatt tgcaggtgtg atagaggtag
    11281 aggactcagg cgttgcctct gtccagcgtg tacttaagaa aatgctattg tcggggttac
    11341 cttcagagtt tgagcttgct gcagttgttc ctgacaagta tctggataaa tatgacgagt
    11401 atttaccaga gactttgctt gctaaagggt atggggcaca ggcgtatgat atagaaggaa
    11461 cgtgcacctg gctgcagaaa caccttcagt agactggata tgtagtcagg gtataaataa
    11521 cttatttata ccctgatttt tttacttccc ggtggactta cttggcttta gtcccggagt
    11581 gttgccagga gtatctttat tatctcgtcg gcgttgatct ggttttcctg tcgatttagc
    11641 aattggtttt ggaccaggtt taagacccat gatagttatc cttttgagat gtaagaggga
    11701 agccctcaac attggtatat tggatactga gaaatttttc aatgggagtg ataaacggcc
    11761 gaatgattaa ctcgatattg tgatcaacgt ctgttttttg cacactgtag actgactctt
    11821 ggagcagaag gttgctctga gcgaggaatg gacagttaca ctcatcacca acgccaatag
    11881 cctcattacg cgtataaagc tgtattaatc attggggagc agtttaatgc gggattttcg
    11941 acttatggac ttgattcagg tgtcaaaatt aaaatgagca gtgtaaggac agacaagttc
    12001 attaggtatg gttttgcggt tgtggcgata gttgccatac tcattactac tatcacaacc
    12061 cccaatccca caccttatca atatatagtt taccgaatag ttctggctct ggctgccgga
    12121 tgtattggtg cagttctgcc tggtttcctt gaagtaaaat ttaatgggtg gttaagagca
    12181 tctggcgcag tggcgatctt cgctatagtg tttttcataa gcccagattt gcttcaacaa
    12241 aatcctgaat ctgcaagtaa acctgtaccg cctactgtga ttgatgcata tgccgttaat
    12301 acttccaatc gcgacagata cctcgaatta tttcgaacag gacagttcgg tcagcgggac
    12361 aagctgcgca tcggttgtgt tgagtggagt gaatcatcgt gcgtggctgc tggtaatttt
    12421 ttgcgattgt taagcgaagc tggctgggaa atcgattctg acgctgtatt cagaatgcaa
    12481 ccatccgtgc cagttgaggg ggtatcgatt gtaagccgtg gcgatgatct ggtcggtttg
    12541 ccaaaagtac caccccacat gggccgttgg agtcgatcag acattagtta tgaaattttg
    12601 acagcggcat ttaaattgat gggagttccg gtttattttt ccagtgaccc gacattacaa
    12661 ccaggtacta ccggagtgta ctttggaccg aaaccgaaac tggatgcacc agtcatgcaa
    12721 aaagacgaga atgtgcgacg tgagcttctc cgctacgtcg gtttgggaat gactattcag
    12781 cgagcctgct ctcagcagcc cgtcgaactt tgtgggggtg aaatcttttc ttgggaaacg
    12841 tcggtatctt cgttcctaag gcagcagaga ttcaactccg atgccgtaaa cagatggctt
    12901 gccttgccgc aggttaatgc ggcttcggca actgcagaca tgaaaataaa gctagatttg
    12961 ttaatgtcat ttgttctggg catcgagtaa ctatacctct tgcgaggatg attgagcgtc
    13021 taatggacca gcttagccgt tagcgctatt tgtttacgta agcctgtgga atccaactag
    13081 tgcttctacg atgcgttgtt tggtgaaaaa aaagtgttga agcactggtt ttagacaact
    13141 aaagccacga tttgctcatg cgtcgaaaat gtagtcgtct actgtgtagc acggaggcga
    13201 tattcgtacg cttacacttg ccgataggcc actggggagt gttcttggca ctaagctgcc
    13261 aggcccgaag gtctgctatg agcgaggggc tgacattcct attggcattc ggtgtgagtt
    13321 atcgggggcg gtcatgcggc atacttccga tacaggcgtt tccagctctg cctgtttcag
    13381 ggttatatta atctgcttta gaattaatcg tggctttagc atctgcacat cgtgctggag
    13441 aaacctgagt gaactaaatc atattccctt tcttcagcta atcaattgat agttatgcgg
    13501 aaaaagttac tttgcttgtc aataatccat ttcacatccg ttaatccaat gctatgcgtc
    13561 ttcgcattaa tctggaaagg tagtaagtga aataaaaact tagccaatga ctaatatctg
    13621 aggatacttt gtcatgaaaa gtatgcaatc aaaaacgggc tctccactcg ttcgaactga
    13681 agccgagcta gaaagccggc ttacttcagc actaaacata gcatttccta acattcctcg
    13741 cgaagatctt atcgaacagc gccattttac cgttcggcta ggccatggaa cttacaaaat
    13801 agatagcgcc gcacactgga aaaaatacgg gcgagcggat gttttgatct ttcatcggga
    13861 gagaccactt gcggttattg aactgaaacg tgaagacctg acactgaccc atgatgatta
    13921 tgaacaggct caaagctacg ctaaccagtt aacaccacgt ccgcctctcg ttgtagttac
    13981 gaacggtaaa gatacgcgcg tttatgactc aagtaatgga caacagtggt cgggtggaca
    14041 ggatgcctcg gcagcggtaa acaagatgct cgccaattct gcaaagttgg cggcggctga
    14101 catgcgctgg gctattgaag ccttgatggg gcgagaaact aatgcttggg tgccagctgt
    14161 gcgagaagaa acagcccggc tgctgattga tataactgat cagcctgggc attcagaaca
    14221 tccatttgcc aacaacctac tttttcctcg caaaatcacg tctcttgtaa ttgaatctgc
    14281 tgtgatgggt acagctttca ctatcattga gggtgatgca caaagcggaa aaagcagttg
    14341 cctccgtgaa atttcgctaa aaacggaaag tagcgatctt ttggctgtcc tgatgttacg
    14401 aggttccgga ccaggactat ttcaggctct ggccaatctt tttgcagctg aatttgaatg
    14461 gaatttaacc tcaaatgatg cacgtaactg gttaagacga atgtctaact gcactgaagg
    14521 tccatcgctt atgcttgcta tcgacgacgt tgaaccaggc tcccaaatgg ctactgatct
    14581 tgaggaactt gcgggtatac gttttggcaa caggctggtg gttgttctga cgacctatca
    14641 tgccaacgcg ttactgaaaa atccaaacgg acgaactccg tctgcaattg gtagccggtc
    14701 gaaggtattt aaaacatcgc ctatgtccct agatgaattt aagctggcgc aacagattct
    14761 ctcggaccag cggatagttt ttcaacaggg agcagaatac gccgatgact accgctcgcc
    14821 ttgggttctt cgcactattt atgatgacat tgtgcgcaat catcaatacc agaaaacgga
    14881 tcttatcgcc tatcttcctc catcacccgg tatggaactt atagatgctg cgcaaaagag
    14941 ctatgagagt cagtatgatc ttcttcgtta ttatcgggtt cttgcacgct gcgcactagc
    15001 tgacacaaac tcccactcag tagaattaat gtttgctaaa gcgaatggat ttgtcgtgcg
    15061 gtatgacgca ctttctgacg aagctcgtgg tgtagtgaat gagttaaaac atatgggggc
    15121 agttcgtatt tttcgccttt caggatggga agatgttgtg gtgccgacag ttcccgcagc
    15181 ttaccttctg gaactgtcgg atgctgtttg tgatgaactg gttttacggg cagaacaaga
    15241 ccctcaagac gccggggctt ggcttggcga acggctagac gccacttatc ttggagatat
    15301 gatcggtgct caagccatac gccgtatggc agctaaagag agatatttca gctttggaat
    15361 tattcagggc cttctcagca ttgagccata taaagaacct ataaaaaacg gattgtttac
    15421 tttagccatg ccagacaacc aacaagtcaa tctaaagatt gaggatggat tagcgtggat
    15481 ttctaaacac ggggatgatg caaagagtgt tctggtgaat ttagaggatc aaatcccaaa
    15541 ggtcatttct aaatcaacca gttggatgat actcgggcaa ctagcgaaac tgccgtcagc
    15601 agaggtgggt gacgatgatc agcgtataga cgcctatatt ttactgagca ttgggcgctg
    15661 cccatttcct ctaattcgca cgaatataga aggattgcct tactttgagc ataattttgg
    15721 cgatcagggt gatgttcttt gcctagaaaa agcgtctatt gaagttgcta ctcaggcgat
    15781 ggctgattta ttttcagccc catggctcta tgcggaccag tgggtggata cagctatcgc
    15841 gaccggttct atacatttac tgcatcgttt gtttgctgct ttaaacacag tgatattgcg
    15901 tagaataccc gtgcaatccg actgggctaa tgaagcactt aatcaacgtg tctcaccagc
    15961 ccttaaggaa gccatacgat cattatcttc gtgactaagc aatgggattt taatacataa
    16021 cgagcatctg tccacgcaag ttaacaattg ccttggctcg atattttggt ttctagtgca
    16081 tatatgctga tctgctcttc gttgatctga tcttacccac caatagtgga cacaggacta
    16141 agtgagtaaa ctctcaacca gaggtgactc atgacaaaac cagtatcaat cagcaagaag
    16201 ccccgtgaac aacattcgcc tgaatttcgt aacgaagccc tgaaactcgc tgaacgcatc
    16261 ggtgtggccg ccgcagcccg tgaactcagc ctttatgaat ctcagcttta tgcctggcgc
    16321 agtaaacagc agcaacaaat gagttcgtca gagcgcgaaa gcgaactggc cgctgaaaat
    16381 gtccgcctta aacgacaact ggcggagcag gctgaggaac tggccatcct ccaaaaggcc
    16441 gcgacatact tcgcgaatcg cctgaaatga agtatgtctt catcgaaaat catcgggcag
    16501 agttctgcat caaagcgatg tgtcgtgtac ttcgggttgc ccgcagcggc tggtatgtct
    16561 ggctcaggcg tcgtcaccag atgagccttc gccaacagtt tcggctcacc tgcgatgccg
    16621 ctgtccataa ggcattcttt gaggcaaagc agcgatacgg tgctccccgc cttgctgacg
    16681 aactgccgga gttcaatatt aaaaccattg ccgccagcct gcgtcgtcag gggctgcggg
    16741 cgaaagttca gcccggtcag ctaccgtgca catggcctgc ccgtattgga gaatctgctg
    16801 gagcaggact tcagcgccag aggcccgaac cagaagtggg cgggtgacat cacgtacttg
    16861 cgtaccgatg agggctggtt gtatctcgca gtagtcatcg acctgtggtc acgcgccgtc
    16921 attggctggt cgatgtcacc gcgaatgaca gcacaactgg cctgtgatgc actacaaatg
    16981 gcgttgtggc ggagaagacg cccggaaagc gtcattgttc atacggaccg tggtggtcaa
    17041 tactgttcag gggattatca ggcgctgctg aagcgacaca acctgcgtgg cagtatgagt
    17101 gcgaaaggct actgttatga caatgcctgt gtggaaagct tctttcattc gctgaaggtg
    17161 gaatgtatcc acggggaacg ctttagcagc cgggaaataa tgcgggcaac ggtgtttaat
    17221 tatatcgagt gtgattacaa tcgctggcgt cgtcacagtg cctgtggcgg tctcagcccg
    17281 gaacaatttg aaaaccataa tctcgcttag ggccgtgtcc acattacgtg ggtaggatca
    17341 attttcctga tgaccccatc gacatagtat tttttcaaag caagaattgc cttctcgcta
    17401 tgtattcctg atagcttgat caggatatca aagtctcttt cagatatatt cccctttgtc
    17461 atgtgtcact ccatgaatca aatttcatag taatcaatct ttctttgatc gacttataga
    17521 taataagatc agaaatgata aaaaagtaac gcatatttct tctcgtcatg tctacttata
    17581 aaatttaaat gaactaacct gaactactta cactggaata tcattatatt ggaataatta
    17641 taaaactgaa caaaatggtc aatgtaatct ggttaattta taaatattta cattgcgtga
    17701 tgatatttaa ttccagtgtt aagtaatgtc gcatacctat tatt
//
LOCUS       DACAOP010000092        17351 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.092, whole genome shotgun sequence.
ACCESSION   DACAOP010000092 DACAOP010000000
VERSION     DACAOP010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17351
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.092"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            52..2229
                     /gene="sinH"
                     /locus_tag="IT892_003471"
     CDS             52..2229
                     /gene="sinH"
                     /locus_tag="IT892_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001317981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like inverse autotransporter SinH"
                     /protein_id="HAP3136649.1"
                     /translation="MLRWKRCIILTFISGAAFAAPEINVKQNESLPDLGSQAAQQDEQ
                     TNKGKSLKERGADYVINSATQGFENLTPEALESQARSYLQSQITSTAQSYIEDTLSPY
                     GKVRSNLSIGQDGDLDGSSIDYFVPWYDNQTTVYFSQFSAQRKEDRTIGNIGLGVRHN
                     FNEWLLGGNIFYDYDFTRGHRRLGLGGEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEE
                     RPARGWDIRAEAWLPSYPQLGGKVVFEQYYGDEVALFGTDNLEKDPYAVTLGLNYQPV
                     PLLTVGADYKAGTGDNSDVSINATLNYQFGVPLKDQLDSDKVKAAHSLMGSRHDFVER
                     NNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEAAVGLEKCKWTINALINHHY
                     KIVAASWQAKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDKAEQEKLNTWR
                     VRLALEDEKGNRQNSGVVEITVQQDRKIELIVNNIANVPEENNHSHEASAQADGVDGV
                     VMDLDVTDSFGDNTDRNGDALPEDNLTPQLYDAQDKRVTLTNKPCSTDNPCVFIAKQD
                     KEKGTVTLSSTLPGTYRWKAKAAPYDDSNYVDVTFLGAEIGGLNAFIYRVGAAKPSNL
                     IGKDKEPLPLNNTYRFVLWRDINKDGVFQQVEKLTDEEMAQYDYKWEFTGKSINGEVG
                     AQANTSNEDIVIPATNREAAQTYGAQAGDGLQGYGLRVLYTKK"
     gene            2284..3261
                     /locus_tag="IT892_003472"
     CDS             2284..3261
                     /locus_tag="IT892_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136650.1"
                     /translation="MKQDKRRGLTRIALALALAGYCVAPVALAEESAWVDSGETNIFQ
                     GTIPWLYSEGGSATTDADHVTLTSDLKGARPTGSETDKRLYSGDKLTVSWEIGDTEGD
                     VDLGGLGDNAKTIDTIRWMSYKDAQGGDPKELATKVTSYTLTDDDRGRYIGIEITPTT
                     QTGTPNVGTALHLYDISTASGGGSDSDNVAPGPVVNQNLKVAIFVDGTSINLINGSTP
                     IELGKTYVAKLYSDENKNGKFDAGTDADVTANYDFRWVLSGSSQQLGTSGGIVNSSFD
                     NNNLAIPATNDEARTNLNGPARDGKEALTIPTNGDGVQGYKLHIIYKHK"
     gene            3382..11424
                     /locus_tag="IT892_003473"
     CDS             3382..11424
                     /locus_tag="IT892_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RatA-like protein"
                     /protein_id="HAP3136651.1"
                     /translation="MSLTLNKILVLCALLISAMLPGWSWAESAWQDSSDTVGEFNGTV
                     PTADSASIPVYQGSVFLDPAKTHEVAFTAKPSEFSADISVSKLLVTNPQDREGDIIST
                     PRWENQTPPTVSLVWADAATPDTLLDPQPVADRSFCAQGLAGRSLVAWAQPDPQQTMP
                     LLYLLTSTGYPYESVLTLADQKVTLKIAPAQGDLISVSAAGYDESSGAAKTTVGGSIT
                     LTVTTKDCVGNVVGNIPFVIKRKDAENRLGVVNNTAPVKLGTTELTTTATEYRGSTDA
                     NGVATVTVTQANGPGVKTPLVASLAGIAQASETAVIFTVLTSPDVPQATMWGHMPDTL
                     KALDYTFSRPKLAAEVDNEDGTVNDHNETWSTFTWSGADKHCDILPGMRQFGALATVV
                     PTSVQDVAGWPMQGNYYWSSLAGMSGQHHAADVSNRSEAQKPDDTTFIVSCVDKEAPD
                     VEPKLVLTPGSYDSTIKAMKVKVGEEASLRLTITDSKNNDQPLAYYYFSLHLDDGVNR
                     KNQTDAAWEAYPVQIDGGSNVRKVDAHTYEGITDANGEASLTLTQPGGVGVKTHITAR
                     MRSDFTASDEKDVIFTVITSPDTDKARMWGHMLGIIEANNIFKRPRLADETANELGAV
                     RENNEDWALFDQNSSMQAECGLGHIPSQSSLHSLFAAHPANVIGTEYGWPTLQKAYLS
                     AVEETSHASVNLATGNIDTYSGFKQNYLSCSGNEMVAQIAATTDHDVSTSSRAQAKVG
                     ETITMTVRTFNALNNAPVPYTAFTITKDMGKNRQGQTTGFDDPTRGAIEMNGTLYGTS
                     QPSLVYAGTTDAQGFATVEIKQPQGVGLATPLNIAPVNSYIPNTVNYNVIFTTLTSPD
                     AVGAQMWGHMDETITVDALTFARPRLAAEVSSPDGTLTENNEVWSRVSQANTSSTSKG
                     GCGANMLPRRSQLNALYDANSGNAVQTVHGWPTQRQPYWSSSPADQVPHYYTIALNDG
                     ARTVGGSTAVYVSCLTTANNPASSITLEVVDPAQWNAAANAAKLKKGETLQVKVTVKD
                     AQGNPLGDMPFTLKRGDGYTRSNEKHIAGSGDALVAPVVINSGLADETSLNDTAAAYS
                     AMTGSDGTKILTITRPDTHGTKTSLTAALYSDTTKKATLDTIFTVVTSPDSDKAKMWG
                     HMPETVTAVDGTVFKRPLLLKELSSTSGRTAIAEDNEDWAQFTQTQATSTSSNGCGSE
                     YVPSQAGLESLYEANRGNAMKTVQGWPVASSYLSSTTGSSSLEQRDFKAVNLSSGTSS
                     IIPSATKELLTCQTTPIVKASQIVLEAADPTKFDSTNNVVKAKKGEEVVVRVTTKDSQ
                     GNPVGNTAFTLKRNLSVNRANASTTVTAGALIVTDAWGNTQSNFSSTTALIYGVTGAD
                     GTTTLALKQDNTTGLKTELTAMLDTDNNVKSMLPVVFTVITSPDTPKAKFWGHMAETM
                     TGAGGLIYKRPLLQDELSVTTSRSSFQEDGESWSLFSPDQSNNTSVNGCGAGYVPIES
                     ELESLYADEGYVPIHDVTGWPVSRAYISSTVVAYYTQTFNFKAVSLKTGDGTEVMSSS
                     LGLLSCRATPVAVTSHIIVEANDATQFVKVDETLSALKRKKGDDAVIRVVTKDAQGNV
                     VPNVPFILKREGSTNRQNVQLSNRTITVINAAGTSARVDTPSISLYAVTGADGTATFT
                     VKQDDSIGLVTNVYAQAYQSSLESNKLPVMFTVITSPDTPLASYWGHMAETFTTRSGT
                     AFKRPLLSAERSSGQSFIEDNEEWAVLRSATKGDIDKSGCDVHYQPLLSELQALYDEH
                     PSRAIKTDLGIPVNSYWWAYDMVAYAGNWYDQYIYLLNGSSGRASSTTSALMLCLVNP
                     HPEAASIEMTSTAEDATKTASNDGRPSATAKKGEVIPMTVTVRDSAGNPLPGASFNLK
                     RGTALNRAKAAYDASADDLTIIPVEPTGVTSILYGDGTQALLKTGSDGKATFEVSQNS
                     SYGLSTPLSAELMRDTSKSVTLDVIFTVITSPDSPKAKYWGHMPETFTSSAGVTFKRP
                     LLAAEATTGSSVNGNNETWSYIYSTQKATADCSLEYQPRLSELQGLYDDHPNGALTKD
                     LGLPIASGNWWIYELLNSNGSSWYYQVFNLSTGRVSSALSPVALMLCLAQPHSKPSSV
                     TLTSIAFDETRTASNGGTPSASAKKGETIPLVVTVKDQNGNLVSGEGVTLQRAQAKSR
                     SGIRPSSLADDLIVDVVTPTATRISFAQDTAKWLGFTGSDGTVTFNVTQNATTGLATP
                     FTVSLAQDPQITSNLDLIFTVVTSPDAQDADYWGHMPETVTAANGTVFERPKLWKELP
                     STSGVNKTNNNNEDWPYFSSTTKANASLSPCEEARQPLLSDMKSLYQRYPNNTLTTET
                     GWSVYYYWWAQDKTTDGKNQSLNMKDGTTTLNGNAAYQACLVSARATVSSVTLTSTAF
                     DADSQAAKVKKGEAMPVTVTVKDSAGNTVPNVEFTLKRGDASPRNAGATLYGDVVAMD
                     DLIVQPLSGSAVTLSESGNTISGMTGADGTASFTLRQDNTPGYKTPLTVTLANYASAT
                     DTLDAIFTVPTSPNVSSAHFWGHMADTVVVNGKSLHRPLLTTELPSGANPVSSPIINY
                     ENWASAHIIDASKWDIARQCGSIENAPTYNELELLHTVFNSLGWPSSPSFPYLSSQQC
                     GMDEGTGAQDCSITLMNKPGLVTCFQ"
     gene            complement(11484..12860)
                     /gene="xseA"
                     /locus_tag="IT892_003474"
     CDS             complement(11484..12860)
                     /gene="xseA"
                     /locus_tag="IT892_003474"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000937953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAP3136652.1"
                     /translation="MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPAS
                     GHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESM
                     QPAGEGLLQQKYEQLKTKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVL
                     KRRDPSLPVIIFPTAVQGDDAPGQIVRAIEMANQRNECDVLIVGRGGGSLEDLWSFND
                     ERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQS
                     ARQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQL
                     KRAGQQQQRLTQRLNQQNPQPRIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTH
                     LEAVSPLSTLARGYSVTSAADGAVLKQVKQVKAGDTLTTRLGDGVVISEVSAVTKTRK
                     PRKKAANP"
     gene            13022..14488
                     /gene="guaB"
                     /locus_tag="IT892_003475"
     CDS             13022..14488
                     /gene="guaB"
                     /locus_tag="IT892_003475"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004159092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAP3136653.1"
                     /translation="MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPM
                     LSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLP
                     TTTLREVKELTERNGFAGYPVVTEENELVGIITGRDVRFVTDLSQPVSVYMTPKERLV
                     TVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRL
                     RVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGG
                     NVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIP
                     VIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLG
                     AMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTI
                     DELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS"
     gene            14557..16134
                     /gene="guaA"
                     /locus_tag="IT892_003476"
     CDS             14557..16134
                     /gene="guaA"
                     /locus_tag="IT892_003476"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP3136654.1"
                     /translation="MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEA
                     QIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEA
                     SNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
                     ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAV
                     ARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDM
                     FGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQ
                     GTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELG
                     LPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTV
                     FLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGIS
                     RVVYDISGKPPATIEWE"
     gene            complement(16229..16768)
                     /locus_tag="IT892_003477"
     CDS             complement(16229..16768)
                     /locus_tag="IT892_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136655.1"
                     /translation="MKKVFLCAILASLSYPAIASSLQDQLSAVAEAEQQGKNEEQRQH
                     DEWVAERNREIQQEKQRRANAQAAANKRATTAAANKKARQDKLDAEASADKKRDQSYQ
                     DELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANRNMTEGGR
                     DLMKSVGKAEENKSDSWFN"
     gene            complement(16784..17302)
                     /locus_tag="IT892_003478"
     CDS             complement(16784..17302)
                     /locus_tag="IT892_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HAP3136656.1"
                     /translation="MMKFKKCLLPVVMLASFTLAGCQSNADDHAADVYQTDQLNTKQE
                     TKTVNIISILPAKVAVDNSQNKRNAQAFGALIGAVAGGVIGHNVGSGSNSGTTAGAVG
                     GGAVGAAAGSMVNDKTLVEGVSLTYKEGTKVYTSTQVGKECQFTTGLAVVITTTYNET
                     RIQPNTKCPEKS"
BASE COUNT         4376 a         4348 c         4620 g         4007 t
ORIGIN      
        1 atacaatatt aaagcttatt tttgactgta tcattgtcac agggaaagtg catgctgcga
       61 tggaaacgct gtattattct aacatttatc tctggtgctg ctttcgcggc accagagata
      121 aatgttaagc aaaacgaatc gttacctgat ttaggtagcc aggcagcaca gcaggatgaa
      181 caaaccaaca agggtaaatc gctgaaagag cgcggagccg attacgtcat caactccgcc
      241 acgcaagggt ttgaaaactt gacccctgag gcgctggaat ctcaggccag aagctatctg
      301 caaagtcaaa tcacctcaac cgcacaatct tatattgaag acacactctc tccctacggt
      361 aaggtccgtt cgaacctctc cattggccag gacggcgatc tggatggcag ttccatcgat
      421 tattttgttc cctggtacga taatcaaacc actgtttatt tcagtcaatt ttctgcgcag
      481 cgaaaagaag atcgtacaat cgggaatatt ggtcttgggg taagacataa ttttaatgaa
      541 tggttattgg gtggaaatat attttatgat tatgatttta cccgaggaca tcgccgttta
      601 ggtttaggcg gcgaagcgtg gactgattat ttaaaattct ctggcaacta ttatcatccg
      661 ctttctgact ggaaagactc tgaagatttc gacttttatg aagaacgccc tgcgcgcggc
      721 tgggatattc gtgccgaagc ctggttacct tcttatccgc aactgggggg caaagttgtc
      781 ttcgagcaat attacggcga tgaagtcgcc ctttttggta cggataattt ggagaaagat
      841 ccctacgcgg taacacttgg actgaattat caaccggtgc cattactaac cgttggggcg
      901 gactataaag cggggaccgg agataacagc gatgtcagca ttaatgccac tcttaattat
      961 cagttcggcg ttccgctaaa agatcaattg gatagcgata aagtgaaagc ggctcactcg
     1021 ttgatgggca gtcgtcatga ttttgttgag cgtaataact ttattgttct ggaatacaaa
     1081 gaaaaagatc cgcttgatgt caccctgtgg ttaaaagcgg atgccaccaa cgagcaccct
     1141 gagtgcgtca ttaaggacac tcccgaagcg gccgtcgggc tggaaaaatg taagtggacc
     1201 attaacgcgc ttatcaacca ccactacaaa attgtcgctg cgtcatggca ggcgaaaaac
     1261 aatgctgccc gcacgttggt tatgccggtt atcaaagaga ataccctgac agagggtaac
     1321 aataaccact ggaacctggt gctgcccgcc tggcagtaca gctctgacaa agccgaacaa
     1381 gaaaaactca atacctggcg agtacgtctg gcactggaag atgaaaaggg caaccgacag
     1441 aactctggcg tggtggaaat caccgttcag caggaccgta aaatagagtt gattgttaat
     1501 aacatcgcga acgtgccgga agagaacaac cacagccacg aagccagcgc tcaggcagat
     1561 ggcgttgatg gtgtggtgat ggatctcgat gtaaccgaca gctttggcga taacaccgac
     1621 cgcaatggcg atgcgctgcc ggaagataac ctcacgccgc agctttacga cgcgcaggac
     1681 aaacgagtga cgttaaccaa caagccttgc tcgaccgaca acccctgcgt ttttatcgct
     1741 aaacaagata aagaaaaggg cactgtcacc ctctccagta ccttacccgg cacctatcgc
     1801 tggaaagcaa aagctgcgcc ctacgacgac agtaactatg tggatgtcac tttcctcggg
     1861 gcagaaattg gtgggctaaa tgcatttatc tatcgtgtgg gggcggctaa acccagcaac
     1921 ctgataggta aagataaaga accgctgccg ctcaacaaca cttatcgatt tgttttgtgg
     1981 cgtgacatca ataaagacgg tgtcttccag caggtcgaaa aactgactga cgaagagatg
     2041 gcgcagtacg actacaagtg ggaatttacc ggcaagagca tcaatggtga agtgggtgca
     2101 caggcgaaca cttccaatga ggacattgtg attccggcca ctaaccgcga agcagcgcaa
     2161 acctatggcg cacaagcggg agatggcttg cagggatacg gtttacgcgt gctgtatacc
     2221 aaaaaataag attggcgtaa ggccagtcgg ccagtcgctg aaggttcatt aaggagagca
     2281 tcaatgaagc aggataaaag acgcggtctg acccggatcg cattggcgct ggcactggca
     2341 ggttattgtg tggcacctgt ggcgctggcg gaagaaagcg cctgggtcga cagcggcgaa
     2401 accaatattt tccagggaac cattccgtgg ctctattcgg aagggggaag cgctacgaca
     2461 gatgccgacc atgtaacgtt gacttctgat ctaaaaggcg ctcgcccgac aggcagtgaa
     2521 acggacaagc gtctttactc gggtgataaa ttaaccgtaa gttgggaaat tggtgatacc
     2581 gaaggcgacg tggatcttgg gggattgggc gataacgcaa agactatcga tactatccgc
     2641 tggatgagct acaaggacgc tcaggggggc gatccgaaag agctggcaac gaaggtgacc
     2701 agttacactc ttaccgatga cgaccgtggc cgttatatcg gtattgaaat tacgccgacc
     2761 acgcagaccg gtacgccaaa cgtcgggact gcgctgcatc tttatgacat ttccactgcc
     2821 agcggcggcg gaagcgacag cgataacgtt gcgccagggc cggtggttaa ccagaacctg
     2881 aaagtcgcca tctttgttga tggtaccagt atcaacctta tcaacggcag cacgccaatc
     2941 gaacttggca aaacctacgt ggccaaactg tactcggatg agaacaaaaa cggcaagttt
     3001 gatgcgggta ccgatgctga cgttaccgcc aattatgact tccgttgggt actttctggc
     3061 agcagccagc agctcggcac ttcgggtggt atcgttaact caagcttcga taataacaat
     3121 ctggccatcc ctgcgaccaa cgacgaagcc agaaccaacc ttaacggtcc tgcgcgcgat
     3181 ggtaaagagg ctcttaccat tccgacaaac ggcgacgggg tacagggtta caaacttcac
     3241 attatttaca aacacaaata acgcgtactc agcagcattc ccgcaaggga atgctgtttc
     3301 cgcatatttt gcttaatccc ggattaagca aaatatgttg atgcgacaag cgtccgttta
     3361 acaaccggtg gagtttctgt catgtccctg accctgaata aaatccttgt gttatgcgca
     3421 ttgctgataa gcgcaatgct gcctgggtgg tcatgggcag aatctgcatg gcaagactct
     3481 tcagatacgg tcggcgaatt taacggtacc gtgcccaccg ccgacagtgc cagcataccc
     3541 gtctaccagg gcagtgtctt tctggatcct gcaaagacgc atgaggtagc gtttaccgct
     3601 aaaccgagtg aattcagcgc ggatattagc gtctctaaat tgctcgtcac caatccgcaa
     3661 gacagagaag gcgatatcat ttccacccca cgttgggaaa accaaacgcc accgacagta
     3721 tctttagttt gggcggatgc cgcgacgccg gacaccttac tggacccaca gccagtcgca
     3781 gatcgctcgt tttgcgctca gggacttgcc gggcgttcgc tggtcgcctg ggcgcagcct
     3841 gatccccaac agaccatgcc gctgttatat ttactcacct cgacgggcta tccctatgaa
     3901 agtgttctga cgctcgccga tcagaaagtg acgctgaaga ttgcgcccgc gcagggtgac
     3961 cttatttccg tcagcgccgc gggctatgac gaatcctccg gtgcggcgaa aacgacggtt
     4021 ggcggcagta tcacgttaac ggtcactacc aaagattgcg tcggtaatgt tgtggggaat
     4081 attccttttg ttatcaaacg caaagatgct gaaaaccgct tgggtgtggt gaacaatact
     4141 gcgccggtaa aactgggcac gaccgaatta accaccaccg cgacggaata tcgtggttct
     4201 accgatgcga atggtgttgc cacggttacg gtcacccagg ccaacggccc tggtgtaaaa
     4261 acgccgttgg tcgcgagcct cgcgggtatt gctcaggcca gtgaaacggc ggtgatcttt
     4321 accgtcctca ccagcccgga tgtcccgcag gccacaatgt ggggtcatat gcccgatacg
     4381 ctgaaggccc ttgattacac ctttagccga ccaaaactgg cggcggaagt cgataatgaa
     4441 gacggtacgg ttaacgatca caatgaaacc tggtcaacct tcacctggag tggcgcggat
     4501 aaacattgcg acattttgcc cggaatgcgt cagttcggtg cgctggcgac ggtggtgcca
     4561 acgtcagtgc aggatgtggc tggttggccg atgcagggta actactactg gtcatcactg
     4621 gcggggatga gcggccagca ccatgcggcg gatgtttcga accgcagcga agcgcaaaaa
     4681 ccggacgata cgacgtttat tgtgagctgt gtcgataaag aagcgcccga tgttgaaccg
     4741 aagctggtac tgacgccggg cagctatgat tcgacgataa aagcgatgaa agtaaaggtg
     4801 ggggaagagg cttctttacg cctgacgatt accgatagca agaacaacga tcagccgctg
     4861 gcgtactact acttttcgct gcatctggat gacggcgtta accgtaagaa tcaaactgac
     4921 gccgcgtggg aggcgtaccc ggtacaaatt gatggcggca gtaacgttcg caaagttgac
     4981 gcccatacct atgaagggat cactgatgct aacggagagg cctctctgac gctgacccag
     5041 ccaggcggcg tgggggtgaa aactcacatc accgcgagaa tgcgcagtga ttttactgcc
     5101 tcggatgaga aagacgttat ttttacggtg atcaccagcc ccgataccga caaagcgcgg
     5161 atgtggggac atatgttagg cattattgaa gcgaacaata tctttaaacg cccacggctg
     5221 gcggatgaaa ccgccaacga actgggagca gtgcgggaaa ataacgaaga ctgggcgctg
     5281 tttgatcaga atagcagtat gcaggctgag tgtggtttag gtcatattcc gagccaaagc
     5341 tcattgcaca gtttgtttgc cgcacatcca gccaatgtca tcggcaccga atatggctgg
     5401 ccaacgttgc aaaaagcgta tcttagtgcg gtggaagaga cgtcgcatgc gtcggtgaac
     5461 ctagccacgg gcaacatcga tacctattcc ggctttaagc aaaactacct ttcttgttcg
     5521 ggcaatgaga tggtcgccca gattgctgcg accaccgatc atgatgtttc cacaagcagc
     5581 agagcgcagg cgaaagtggg tgaaacgatt accatgacgg tacgcacctt taatgccttg
     5641 aataatgcgc ccgtgccgta taccgcgttc accatcacga aagatatggg gaaaaatcgt
     5701 caggggcaga ccacgggttt cgatgatcca acccgcggcg caatcgagat gaatggcacg
     5761 ctctacggaa catcgcaacc gtctttagtc tatgcaggta ctacggatgc gcagggtttt
     5821 gctactgtgg aaattaagca accgcaaggt gtgggcttag cgacgccgct gaatattgcg
     5881 cctgtaaact cctatattcc caatactgtt aattacaatg tgattttcac tacgctcacc
     5941 agtccggatg cggttggcgc gcagatgtgg gggcatatgg atgagacgat taccgtcgat
     6001 gcattaacct ttgcccgacc ccgactggct gcggaagtgt ccagcccgga cggcacatta
     6061 acggaaaata acgaagtatg gtcgcgcgtt agccaggcca acacttccag caccagtaaa
     6121 ggtggctgtg gtgccaatat gctcccacgc cgttcccagc ttaacgcgct ctatgatgct
     6181 aacagtggta acgccgttca aacggtacac ggttggccaa cgcagcgtca gccctactgg
     6241 agcagttcgc ccgcggatca ggtgccgcat tactacacca tagccctcaa cgatggcgcg
     6301 cggaccgttg gtggtagcac ggcggtttat gtcagttgcc tgacgacggc taacaatcct
     6361 gccagcagca ttacgctgga agtggtggac ccggcgcagt ggaacgcggc agcaaatgcg
     6421 gcgaagctga aaaaaggcga aacgctacag gtgaaggtga cggtaaaaga tgctcagggc
     6481 aatccattgg gtgatatgcc ttttacgctg aagcgtggcg atggttatac ccgatcaaac
     6541 gaaaaacaca ttgccggtag cggtgatgcg ctggttgcgc cggttgtgat caatagtggc
     6601 ctggcggatg aaacttcgct caatgatacc gccgcagcat acagcgcgat gaccggcagc
     6661 gatggcacta aaattctcac tattacccgc ccggataccc atggcacaaa aacgtcgctg
     6721 accgccgcgc tctattcaga cacaacgaaa aaagcgaccc tcgataccat ttttaccgtt
     6781 gtcaccagcc cggacagcga taaggcgaaa atgtgggggc atatgcctga aacggtgacg
     6841 gctgtggatg gaacggtctt taaacgccca ttattgttga aagagttatc cagtacgtcg
     6901 ggtcgaacag cgattgcaga agataatgag gactgggcgc aatttaccca aactcaggcg
     6961 acaagcacat cctctaatgg ttgtggtagt gaatatgttc cctcccaggc cgggctggag
     7021 tcattgtatg aagccaaccg cggcaatgcg atgaaaacgg ttcagggctg gcccgtcgcc
     7081 tcaagttacc tttccagcac gacaggcagc agtagcctgg aacagcgtga cttcaaggcc
     7141 gtcaatctca gttcaggcac cagttcgata attccatcgg ccacaaaaga actgcttacc
     7201 tgccagacga cgccgatcgt caaggctagc caaatcgttc ttgaggctgc ggaccccaca
     7261 aaatttgaca gtacgaataa tgttgtcaaa gcgaaaaaag gggaagaagt cgtggttcgc
     7321 gtgaccacta aagattcgca gggtaacccg gtgggaaata ccgcgtttac gcttaaacgt
     7381 aaccttagcg tcaatcgggc aaatgcgtct acaacggtga cagcaggcgc gctcatcgtg
     7441 acggatgcct ggggtaacac gcagagtaat ttttcctcaa caacagcact gatttatggc
     7501 gttaccggcg cagatggtac gacaacactt gcactgaaac aggacaatac cacgggttta
     7561 aaaaccgaac tgaccgccat gctggataca gataataacg taaaatcaat gcttccggtg
     7621 gtctttacgg tgataaccag ccccgatacc cctaaagcaa aattctgggg gcatatggcc
     7681 gaaacgatga ccggtgcagg cgggcttatt tataaaagac cgttattgca agatgagctt
     7741 tccgttacaa ccagtcgaag ctcttttcag gaagatggag agagctggtc actgttctcg
     7801 ccggaccagt cgaacaacac atctgtaaat ggttgcggtg caggatatgt cccgattgaa
     7861 agtgagctgg agtcactgta tgccgatgaa ggttacgtgc caatacatga cgttacggga
     7921 tggcctgtat cacgcgccta tatctccagt acggttgttg cctattacac tcaaacattt
     7981 aattttaaag cggtttcgtt aaaaacgggt gatggaacgg aggtcatgtc aagcagtcta
     8041 ggactgctaa gttgtcgggc taccccagtg gcggtgacca gccacattat tgttgaagcg
     8101 aacgatgcga cacaatttgt caaagttgac gaaaccctca gcgcactaaa acggaaaaaa
     8161 ggtgacgacg cggtgattcg cgtggtgaca aaagatgcgc agggaaatgt cgtaccaaat
     8221 gttccgttta ttctcaaacg tgaaggatcg acaaatcgcc agaatgtaca gttgtcgaac
     8281 agaactatca ctgtaatcaa cgctgcggga acgtcggcaa gagtggatac tccatcaatc
     8341 tccctttatg cggtgacagg tgcagacggg acagccacgt ttacggtaaa gcaggatgat
     8401 tctataggcc tggtaaccaa tgtgtacgct caggcctatc agtcgagcct ggaatccaac
     8461 aaattacccg tgatgtttac cgtgataacc agcccggata cccccctggc aagttactgg
     8521 gggcatatgg cggaaacgtt cactacgcgt tctggtactg ccttcaaacg ccccttactc
     8581 tctgctgaaa gatcgtcggg ccagtcgttt atagaagaca atgaagagtg ggccgtgttg
     8641 agatcggcaa caaaggggga tatcgataaa agcgggtgcg atgtacatta tcaaccactg
     8701 ttaagcgaac tacaggcatt gtacgacgaa cacccaagtc gtgcgataaa gaccgatctg
     8761 ggtattccgg taaatagcta ctggtgggct tacgacatgg tggcatatgc gggtaactgg
     8821 tacgatcaat atatttatct gttaaatgga tcaagtggaa gagcgtcttc aaccacctcg
     8881 gcattaatgc tgtgcctggt aaaccctcat ccagaggcgg cttctattga aatgacctca
     8941 acggcggagg atgcaacgaa aacggccagc aatgatggca ggcccagcgc aacagcgaag
     9001 aagggagagg ttatcccgat gactgttacg gtgcgagata gcgcaggcaa tccactgcca
     9061 ggtgccagct ttaaccttaa acgaggaact gcgctgaacc gcgctaaagc tgcgtacgat
     9121 gcctctgcag atgatcttac catcatacct gtggaaccta ctggggtaac gtcaatcttg
     9181 tatggggatg ggacgcaggc tcttctgaag acagggagcg atggtaaagc tacgtttgag
     9241 gtcagccaga atagcagtta tgggctgtca acgccgctca gcgcagaact catgcgcgat
     9301 acctcgaaaa gcgtcacgct ggatgtcatt ttcacggtga taaccagccc ggattcgcca
     9361 aaagcgaaat actggggcca tatgccggaa acgtttacca gttcggcagg cgtgaccttc
     9421 aagcgcccat tactggcagc ggaagcgact acggggagct cggtaaacgg taataatgag
     9481 acatggtcat atatatatag tactcaaaaa gcgacggcag attgttcgct ggaatatcaa
     9541 ccgcgcctca gcgaattgca ggggttatat gacgatcacc caaacggggc gttaacgaaa
     9601 gatctggggt tgccgatagc gtcaggaaac tggtggattt atgaattgct taactccaat
     9661 ggtagctcct ggtattatca ggtctttaac ctaagtacgg gacgagtatc atccgcactc
     9721 tctccggttg ctctaatgct ctgcctggca cagcctcact ctaagccgtc aagcgttacc
     9781 ctgacttcaa tagcatttga tgagacgaga accgcaagta acggcggcac accttcggca
     9841 tcggcgaaaa agggcgagac aatcccgtta gtcgtgacag taaaagacca aaatggcaac
     9901 ctggtgagtg gtgagggcgt gacgcttcag cgggcgcagg cgaaaagtcg ttcaggaatt
     9961 aggccctcat cgttggcaga tgatcttatt gtagatgttg tcacaccgac agcaacccgt
    10021 atttcctttg ctcaggatac ggcaaaatgg cttggtttta ccggcagtga tggcacagtg
    10081 acgttcaatg ttacgcaaaa cgccaccacc ggcctggcaa cgccgtttac ggtctcgctt
    10141 gcacaagatc cgcagatcac gtcaaacttg gacctgatat ttaccgtggt caccagccct
    10201 gacgcccagg atgccgacta ctggggtcat atgccagaaa cggtgacagc ggcaaatgga
    10261 accgtctttg aacgaccgaa attgtggaag gagctgccat cgacctccgg ggtaaataaa
    10321 accaataaca ataatgagga ctggccctat ttttcgtcaa ccactaaagc aaatgccagc
    10381 ctcagccctt gtgaggaagc ccggcaaccg ttgctcagcg atatgaagtc actgtatcaa
    10441 cgttatccca ataacaccct tacgacggaa actggctggt cagtttatta ttactggtgg
    10501 gcgcaggata agactacaga tggtaaaaat cagtcgctca atatgaaaga tggcacaacg
    10561 acattgaatg gtaatgccgc ttatcaggcg tgtctggtgt ctgcgcgcgc gacggtttcc
    10621 agcgtcacac tgacctcaac agcgtttgat gctgacagcc aggcggcgaa agtgaaaaaa
    10681 ggcgaagcca tgcccgttac cgtgacggtg aaagacagcg ccgggaatac ggtaccgaat
    10741 gtggaattta ctttgaaacg tggcgatgca tcgccgcgta acgctggggc gacgttgtat
    10801 ggtgatgtgg tggcgatgga cgatctcatc gttcagccgt tatctggttc ggctgttacg
    10861 ctgagtgaaa gcggtaatac cattagtggc atgacaggcg cggatgggac ggcaagtttt
    10921 acgctccgcc aggataatac ccctggttat aaaacgccac tgacggttac tctggctaat
    10981 tacgcttccg cgacagacac gctggacgct atttttacgg taccaaccag cccgaatgtt
    11041 tcctcggcgc acttttgggg acatatggca gacactgtag tggtgaatgg taaatcgcta
    11101 catcgaccgt tgttaacgac agaattgccg tccggggcaa atcccgtatc ctcaccgatt
    11161 attaactacg aaaactgggc ttctgcacat atcattgatg ccagtaaatg ggatattgca
    11221 aggcagtgtg gcagcataga aaatgcaccg acatacaatg aattagagtt gttgcacact
    11281 gtttttaatt cactgggatg gccgtcttca ccaagttttc cttatttgtc ctctcaacag
    11341 tgtgggatgg acgaaggcac tggagcacag gattgtagta tcacgctaat gaataaaccg
    11401 ggtctggtga cctgcttcca gtaaccagca tggcgcatct ggcgtggcct gggagccagt
    11461 gccggatgcg atgctggcgc atcttatgga ttagcagctt tcttacgcgg tttacgcgtt
    11521 tttgttacgg cgctaacttc actaatcacc acaccatcac caagtcgagt ggtcaacgta
    11581 tcgcccgctt tcacctgctt cacctgcttt aacactgcgc catctgcggc gctggtgacg
    11641 ctataaccac gcgccagcgt cgaaagcggg ctaactgctt ccaggtgcgt tactgcatta
    11701 ccaaaccgtt ctcgcgttgc gctcagttgc gcgcgcaacg tttctgccag gcgatattcc
    11761 agttgttgaa ttcgcgtctg tgcgcggtga atacgcggct gcggattttg ctggtttagc
    11821 ctctgtgtta atcgctgctg ctgttgcccg gcacgcttaa gctgattttc cagcgcaaag
    11881 ctcatccgct tttgcaggcg ctcaagcatg gtttgctggc gtgccagccg gagctgtgga
    11941 tgctgctgct gtaagcgatg atggatctgc gtaaaacgac gcgtgcggtt ggcgagataa
    12001 taatccatcg ccatctccag ccgttgacgg gccgattgca cctggcgcag taactcttgc
    12061 tgatttcggc tcactacttc agcggcagcc gagggcgttg gcgcacgcaa atcagcgaca
    12121 aaatcggcaa tcgtcacatc ggtttcatgc ccgacggcac tcactaccgg aatgcggctg
    12181 gcaaaaatcg cccgcgctac acgttcgtcg ttaaaactcc ataaatcttc cagcgaaccg
    12241 ccaccgcgcc caacgatcaa tacgtcacac tcgttgcgct gattcgccat ttcaatggcg
    12301 cgaacaattt gccccggcgc gtcatcgccc tgaacggcgg tggggaagat gatcaccggc
    12361 agagaaggat cgcgacgttt caacacatgc aaaatatcat gtagcgcagc accggttttt
    12421 gaggtgatca caccaacgca atgcgcaggg gagggaagtg gttttttgta ttgctgatcg
    12481 aacagacctt cagcctgcaa tttcgtttta agctgttcgt atttttgttg cagcaaccct
    12541 tcaccggcag gctgcatact ttcgacgata atctggtagt caccgcgcgg ctcgtagagc
    12601 gtaatattgg cgcgaactaa aacctgttgc ccatgctgtg ggcgaaaggt cacccgtcga
    12661 ttgctgttac ggaacatcgc acagcgcacc tgcgcggtat cgtctttaag cgtaaagtac
    12721 cagtgaccgg aagccggttg tgtgaaatta gaaatttcgc cgctgatcca aacctgtccc
    12781 atctcatgct caagcagcag acgaaccgtt tgattcaggc gactaacggt aaaaattgca
    12841 ggggattgag aaggtaacat gtgagcgaga tcaaattcta aatcagcagg ttattcagtc
    12901 gatagtaacc cgccctccgg ggatagcaag cattttttgc aaaaaggggt agatgcaatc
    12961 ggttacgctc tgtataatgc cgcggcaata tttattaacc actctggtcg agatattgcc
    13021 catgctacgt atcgctaaag aagctctgac gtttgacgac gttctcctcg ttcctgctca
    13081 ttctaccgtt ctgccgaata ctgctgacct cagcacccag ctgacgaaaa ctattcgtct
    13141 gaatatccct atgctttccg cagcaatgga taccgtaacg gaagcgcgcc tggctattgc
    13201 tctggctcag gaaggcggta tcggctttat ccacaaaaat atgtccattg aacgccaggc
    13261 ggaagaagtt cgccgtgtga aaaaacacga atctggcgtg gtgactgacc cgcagactgt
    13321 tctgccaacc acgacgctgc gcgaagtgaa agaactgacc gagcgtaacg gctttgcggg
    13381 ctacccggtc gttaccgaag aaaacgaact ggtgggtatt atcaccggtc gtgacgtacg
    13441 ttttgttacc gacctgagcc agccggttag cgtttacatg acgccgaaag aacgtctggt
    13501 caccgtgcgt gaaggtgaag cccgtgaagt tgtgctggca aaaatgcacg aaaaacgcgt
    13561 tgaaaaagcg ctggtggttg atgacgaatt ccacctgatc ggcatgatca ccgtgaaaga
    13621 tttccagaaa gcagaacgta aaccgaacgc ctgtaaagac gagcaaggcc gtctgcgtgt
    13681 tggtgcagcg gttggcgcgg gtgcgggtaa cgaagagcgt gttgacgcgc tggttgccgc
    13741 aggcgttgac gttctgctga tcgactcctc tcacggtcac tctgaaggcg ttctgcagcg
    13801 tatccgtgaa actcgtgcta aatatccgga tctgcaaatc atcggcggca acgtggcaac
    13861 agctgcgggg gcacgcgctc tggcagaagc tggttgcagc gcggttaaag tcggcattgg
    13921 ccctggctct atctgtacga ctcgtatcgt gactggcgta ggtgttccgc agatcaccgc
    13981 cgttgctgac gccgtagaag ccctggaagg caccggtatt ccggttatcg ctgacggtgg
    14041 tatccgtttc tcaggcgata tcgccaaagc tatcgccgca ggtgcaagcg cggtaatggt
    14101 gggttccatg ctggcgggta ctgaagaatc tccgggtgaa atcgaactct accagggccg
    14161 ttcttacaaa tcttaccgtg ggatgggctc tctgggtgcg atgtccaaag gttcttctga
    14221 ccgttacttc cagagcgaca acgctgccga caaactggtg ccggaaggta tcgaaggtcg
    14281 cgtggcctat aaaggtcgcc tgaaagagat cattcaccag cagatgggcg gcctgcgctc
    14341 ctgtatgggc ctgaccggct gtggtactat cgacgaactg cgtactaaag cggagtttgt
    14401 acgtatcagc ggtgcgggca ttcaggaaag ccacgttcac gacgtgacca ttactaaaga
    14461 gtccccgaac taccgtctgg gctcctgatt ctcttcgccc gacttcatgt cgggcgattt
    14521 atattatctg tttcacttgc ctcggaataa gcgtcaatga cggaaaacat tcataagcat
    14581 cgcatcctca ttctggactt cggttctcag tacactcaac tggttgcgcg ccgcgtgcgt
    14641 gaactgggtg tttactgcga actgtgggcg tgggatgtga cagaagcaca aattcgtgac
    14701 ttcaacccaa gcggcattat tctttccggc ggcccggaaa gcaccaccga agaaaacagc
    14761 ccgcgtgcgc cgcagtatgt ctttgaagca ggcgtaccgg tattcggcgt ttgctatggc
    14821 atgcagacca tggcaatgca gttgggcggt cacgttgaag cctctaacga acgtgaattt
    14881 ggctacgcgc aggttgaagt cgtaaacgac agcgcactgg ttcgcggtat cgaagatgcg
    14941 ctgactgcag acggtaaacc gctgctcgat gtctggatga gccacggcga taaagttacc
    15001 gctatcccgt ccgacttcgt caccgtagcc agcaccgaaa gctgcccgtt tgccattatg
    15061 gctaacgaag aaaaacgctt ctatggtgta cagttccatc cggaagtgac tcacacccgc
    15121 cagggtatgc gcatgctgga gcgttttgtg cgtgatatct gccagtgtga agccctgtgg
    15181 acgccagcga aaattatcga cgacgccgta gctcgcatcc gcgagcaggt aggcgacgat
    15241 aaagtgatcc tcggcctctc tggtggcgtg gattcctccg taaccgcaat gctgctgcac
    15301 cgcgctatcg gtaaaaacct gacttgcgta ttcgtcgaca acggcctgct gcgtctcaac
    15361 gaagcagagc aggttctgga tatgtttggc gatcactttg gtctcaatat tgttcacgtt
    15421 ccggcagaag atcgcttcct gtcagcgctg gctggcgaaa acgatccgga agcaaaacgt
    15481 aaaatcatcg ggcgcgtttt cgttgaagta ttcgatgaag aagcgctgaa actggaagac
    15541 gtgaagtggc tggcgcaggg tactatctac cctgacgtta tcgaatctgc ggcgtctgca
    15601 accggtaaag cacacgtcat caaatctcac cacaacgtgg gcggcctgcc gaaagagatg
    15661 aagatgggcc tggttgaacc gctgaaagag ctgttcaaag acgaagtgcg taagattggt
    15721 ctggagctgg gcctgccgta cgacatgctg taccgtcatc cgttcccggg accaggcctt
    15781 ggcgttcgtg ttctgggtga agtgaagaaa gagtactgtg acctgctgcg ccgcgctgac
    15841 gccatcttca ttgaagaact gcgtaaagcg gacctgtacg acaaagtcag ccaggcgttc
    15901 accgtcttcc tgccagtacg ttccgttggc gtaatgggcg atggtcgtaa gtatgactgg
    15961 gttgtctctc tgcgtgctgt cgaaaccatc gactttatga ccgcacactg ggcgcatctg
    16021 ccgtacgatt tcctcggtcg cgtttccaac cgcattatca atgaagtgaa cggtatttcc
    16081 cgcgtggtgt atgacatcag cggcaagccg ccagctacca ttgagtggga atgattttga
    16141 tccctgcact atgaatgaac aaaaccctct gttactacag agggtttttt atcttcaaga
    16201 attataggct tgaagttact tacatcgatt aattaaacca gctgtccgat ttgttctctt
    16261 ctgctttgcc cacgcttttc atcagatctc gaccgccctc agtcatattc ctgtttgcgt
    16321 cagcttcaga ttgcaccaca tcggtttgcg cagctttgtg cttcagttcc tgatcgataa
    16381 attcgttttc tcgcttaacg cgggcttctt ctttcgccag cgccagtttt tgtttctgaa
    16441 tctctaagct gcgtagctca tcttgataac tttgatcgcg ttttttgtcc gcagaggctt
    16501 cggcgtccag tttatcctga cgagctttct tatttgccgc tgccgttgtc gctcttttgt
    16561 tagcggcggc ctgggcgttt gcgcgacgtt gcttctcttg ctggatttcc ctgttgcgct
    16621 ccgcgaccca ttcgtcatgc tgcctttgct cttcattttt accttgctgt tccgcttctg
    16681 cgacagcaga gagttgatcc tgcaatgatg aggcgatagc cggatagctt aaggaagcta
    16741 agatggcgca aagaaaaact ttcttcatga ctcctcctga ttattagctc ttttcaggac
    16801 atttggtatt tggctgaata cgcgtttcgt tatacgtcgt ggtaataaca acggctaaac
    16861 ctgtcgtaaa ctggcactct ttacccacct gggtggaggt atacactttg gtgccttcct
    16921 tatacgttag agaaacacct tccactaagg ttttatcatt caccatagaa cccgctgccg
    16981 cgccaacagc tccgccgcca actgcacctg ccgtcgttcc ggaattgctg ccagacccga
    17041 cgttgtggcc aataacaccg ccagcgactg caccaataag cgcgccgaag gcttgtgcgt
    17101 ttcgtttatt ttgggagttg tctacggcaa cttttgcggg aagaatggaa ataatattaa
    17161 cggttttagt ttcttgtttg gtattcagtt gatcggtttg ataaacatcg gcggcatgat
    17221 catcagcatt tgactggcat cctgccagag tgaatgacgc taacattacc acaggcagaa
    17281 gacatttttt aaatttcatc actattcctt gttatacaca ttacgaaaaa taagacattt
    17341 aagatcatca a
//
LOCUS       DACAOP010000093        17288 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.093, whole genome shotgun sequence.
ACCESSION   DACAOP010000093 DACAOP010000000
VERSION     DACAOP010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17288
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.093"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            33..893
                     /locus_tag="IT892_003479"
     CDS             33..893
                     /locus_tag="IT892_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001306033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 domain-containing protein"
                     /protein_id="HAP3136657.1"
                     /translation="MRLFYLFFQHVEIRQTMSGELTPLGIPQTPSAEFPSAKIWQTLS
                     AKSFPLPRSTYVRLLSVKNADARSFYEKETLRCGWSVRQLERQIATQFYERTLLSHDK
                     SAMLQQHAPAETHILPQQAIRDPFVLEFLELKDEYSESDFEEALINHLMDFMLELGDD
                     FAFVGRQRRLRIDDNWFRVDLLFFHRRLRCLLIVDLKVGKFSYSDAGQMNMYLNYAKE
                     HWTLPDENPPIGLVLCAEKGAGEAHYALAGLPNTVLASEYKMQLPDEKRLADELVRTQ
                     AVLEEGYRRR"
     gene            complement(953..1417)
                     /locus_tag="IT892_003480"
     CDS             complement(953..1417)
                     /locus_tag="IT892_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF386 domain-containing protein"
                     /protein_id="HAP3136658.1"
                     /translation="MMMGEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDN
                     IFMNVMTFNTQSPVEKKAELHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQ
                     LCSTIDNEQAIILKPGMFAVFMPGEPHKPGCVVGEPGEIKKVVVKVKADLMA"
     gene            complement(1414..2289)
                     /locus_tag="IT892_003481"
     CDS             complement(1414..2289)
                     /locus_tag="IT892_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HAP3136659.1"
                     /translation="MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDA
                     LSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIA
                     INDAQAAAWAEFQALDGDITDMVFITVSTGVGGGVVSGCKLLTGPGGLAGHIGHTLAD
                     PHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADAKTIFTRAGQGDEQAQQLIHRSA
                     RTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHD
                     AGLLGAALLAQGEKL"
     gene            complement(2286..2975)
                     /locus_tag="IT892_003482"
     CDS             complement(2286..2975)
                     /locus_tag="IT892_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP3136660.1"
                     /translation="MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQ
                     AGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADII
                     AIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
                     ETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQ
                     WYNTAMKKAVL"
     gene            complement(3023..4513)
                     /gene="nanT"
                     /locus_tag="IT892_003483"
     CDS             complement(3023..4513)
                     /gene="nanT"
                     /locus_tag="IT892_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid transporter NanT"
                     /protein_id="HAP3136661.1"
                     /translation="MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLT
                     EVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLAC
                     GFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
                     AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILY
                     RGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPT
                     GVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYNPHTVANVLFFSGFGAAVGCCVGGFL
                     GDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIG
                     GYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLI
                     GLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS"
     gene            complement(4622..5515)
                     /gene="nanA"
                     /locus_tag="IT892_003484"
     CDS             complement(4622..5515)
                     /gene="nanA"
                     /locus_tag="IT892_003484"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HAP3136662.1"
                     /translation="MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYV
                     GGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDA
                     VSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
                     VGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQ
                     GIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGP
                     VDEKYLPELKALAQQLMQERG"
     gene            complement(5637..6428)
                     /gene="nanR"
                     /locus_tag="IT892_003485"
     CDS             complement(5637..6428)
                     /gene="nanR"
                     /locus_tag="IT892_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417693.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HAP3136663.1"
                     /translation="MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMI
                     RRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADT
                     IIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQ
                     SLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVS
                     YQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK"
     gene            6808..8175
                     /gene="dcuC"
                     /locus_tag="IT892_003486"
     CDS             6808..8175
                     /gene="dcuC"
                     /locus_tag="IT892_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HAP3136664.1"
                     /translation="MFGIIISVIVLITMGYLILKNYKPQVVLAAAGIFLMMCGVWLGF
                     GGVLDPTKSSGYLIVDIYNEILRMLSNRIAGLGLSIMAVGGYARYMERIGASRAMVSL
                     LSRPLKLIRSPYIILSATYVIGQIMAQFITSASGLGMLLMVTLFPTLVSLGVSRLSAV
                     AVIATTMSIEWGILETNSIFAAQVAGMKIATYFFHYQLPVASCVIISVAISHFFVQRA
                     FDKKDKNINHEQAEQKALDNVPPLYYAILPVMPLILMLGSLFLAHVGLMQSELHLVVV
                     MLLSLTVTMFVEFFRKHNLRETMDDVQAFFDGMGTQFANVVTLVVAGEIFAKGLTTIG
                     TVDAVIRGAEHSGLGGIGVMIIMALVIAICAIVMGSGNAPFMSFASLIPNIAAGLHVP
                     AVVMIMPMHFATTLARAVSPITAVVVVTSGIAGVSPFAVVKRTAIPMAVGFVVNMIAT
                     ITLFY"
     gene            complement(8218..8715)
                     /gene="sspB"
                     /locus_tag="IT892_003487"
     CDS             complement(8218..8715)
                     /gene="sspB"
                     /locus_tag="IT892_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HAP3136665.1"
                     /translation="MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPME
                     YARDGQIVLNIAPRAVGNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGAGT
                     MFEPEAAYDEDTSIMNDEEASADNETVMSVIDGDKPDHDDDTHPDDEPPQPPRGGRPA
                     LRVVK"
     gene            complement(8721..9359)
                     /gene="sspA"
                     /locus_tag="IT892_003488"
     CDS             complement(8721..9359)
                     /gene="sspA"
                     /locus_tag="IT892_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein A"
                     /protein_id="HAP3136666.1"
                     /translation="MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKD
                     NPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLY
                     MHRIEKDWYTLMNTIINGSASEADAARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
                     LAPLLWRLPQLGIEFSGPGAKELKGYMTRVFERDSFLASLTEAEREMRLGRS"
     gene            complement(9754..10146)
                     /gene="rpsI"
                     /locus_tag="IT892_003489"
     CDS             complement(9754..10146)
                     /gene="rpsI"
                     /locus_tag="IT892_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP3136667.1"
                     /translation="MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETA
                     RMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAG
                     FVTRDARQVERKKVGLRKARRRPQFSKR"
     gene            complement(10162..10590)
                     /gene="rplM"
                     /locus_tag="IT892_003490"
     CDS             complement(10162..10590)
                     /gene="rplM"
                     /locus_tag="IT892_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAP3136668.1"
                     /translation="MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEY
                     TPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIE
                     IAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI"
     gene            complement(10809..11936)
                     /locus_tag="IT892_003491"
     CDS             complement(10809..11936)
                     /locus_tag="IT892_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HAP3136669.1"
                     /translation="MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTP
                     PAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQR
                     LHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
                     KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTL
                     TQAHLWLSPLHDETRAQMDKLWLALAGGKRENSPTLEINHRPLATMGVENQTLAVSFT
                     TLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIALVDEFYERHVKLVVS
                     AEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG"
     gene            12130..12528
                     /locus_tag="IT892_003492"
     CDS             12130..12528
                     /locus_tag="IT892_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1043 family protein"
                     /protein_id="HAP3136670.1"
                     /translation="MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAE
                     LDEYREELVSHFARSAELLDTMAHDYRQLYQHMAKSSSSLLPELSAEANPFRNRLAES
                     EASNDQAPVQMPRDYSEGASGLLRTGAKRD"
     gene            12682..14049
                     /gene="degQ"
                     /locus_tag="IT892_003493"
     CDS             12682..14049
                     /gene="degQ"
                     /locus_tag="IT892_003493"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegQ"
                     /protein_id="HAP3136671.1"
                     /translation="MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAP
                     MLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKG
                     YVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
                     KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGAL
                     LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEM
                     SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIAT
                     TEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGI
                     KIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESI
                     YLLMR"
     gene            14139..15206
                     /gene="degS"
                     /locus_tag="IT892_003494"
     CDS             14139..15206
                     /gene="degS"
                     /locus_tag="IT892_003494"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane-stress sensor serine
                     endopeptidase DegS"
                     /protein_id="HAP3136672.1"
                     /translation="MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETP
                     ASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
                     QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGN
                     PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL
                     SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGI
                     DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVV
                     VMRDDKQLTLQVTIQEYPATN"
     gene            complement(15269..16207)
                     /gene="mdh"
                     /locus_tag="IT892_003495"
     CDS             complement(15269..16207)
                     /gene="mdh"
                     /locus_tag="IT892_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HAP3136673.1"
                     /translation="MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAV
                     DLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLV
                     QQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
                     LKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKA
                     GGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVE
                     ERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK"
     gene            16642..17112
                     /gene="argR"
                     /locus_tag="IT892_003496"
     CDS             16642..17112
                     /gene="argR"
                     /locus_tag="IT892_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HAP3136674.1"
                     /translation="MRSSAKQEELVKAFKALLKEEKFSSQGEIVVALQEQGFDNINQS
                     KVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSP
                     GAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL"
BASE COUNT         4274 a         4521 c         4315 g         4178 t
ORIGIN      
        1 agcgtgggtt ctctgcaaaa aacttacgcc aaatgaggct tttttacctc ttttttcaac
       61 atgttgaaat tcgccagaca atgtctggcg aattaacacc attgggaatt ccgcagacac
      121 cgtctgcaga attcccatcg gcaaagattt ggcagacgct gtctgccaaa tctttcccct
      181 tgcccaggtc cacctacgtc cgtttacttt ccgttaaaaa cgctgacgcc cgcagctttt
      241 atgaaaaaga gacgctccgc tgtggctggt ctgttcgcca gctagagcgg caaattgcga
      301 cccagtttta tgagcggaca ctactgtcac atgacaaatc agccatgctg caacaacacg
      361 ctcctgccga gacgcatatt cttccgcaac aggcgatacg cgatcccttt gtgctcgaat
      421 ttctggaatt gaaagatgaa tattcagaat ccgattttga ggaggcgctg atcaaccacc
      481 tgatggattt catgctggaa cttggggatg attttgcctt tgttggtcgg cagcgaaggt
      541 tacgcattga tgacaactgg tttcgtgtcg atctgctgtt tttccaccgc cgtttacgct
      601 gcctgctaat cgtcgatcta aaagtgggca aattcagcta tagcgatgcc ggacagatga
      661 atatgtatct caactacgcc aaagagcact ggacgctacc ggatgaaaat ccgcccatcg
      721 gtctggttct ctgtgcagag aaaggagccg gagaagcgca ttatgctctg gcaggtttgc
      781 ctaacaccgt tctggcaagc gaatataaga tgcaactacc tgatgagaaa cgactcgcag
      841 atgaactcgt tcgaacacag gcggtgctag aggaaggcta tagacgccgt taatttcagc
      901 ggtttcgaat tctgcagaca gtgtctgcag aatctttaaa acgaactaag ttttaagcca
      961 ttaaatcagc cttaaccttc accacaacct ttttaatctc tccaggctcg ccgacaacgc
     1021 atcctggttt atgcggttca cctggcataa acacggcgaa cattcccggt tttaagatga
     1081 tggcttgctc gttatcaatg gtgctgcaaa gctgataatc atcctcatgg tggaactctt
     1141 cacactgacg cgcagtgcct gccatgccaa acagaatccg ttcctcaccg tttaataaca
     1201 gctggatatc aatgtattgc tcgtgcaatt ccgctttttt ctcgacgggc gattgagtgt
     1261 taaacgtcat gacattcata aagatattgt cgccctgtaa ttcgtaacga cccggcgctt
     1321 tttcttgcgg tctggcagct aatgccagcg ttaacgcgtc ctgtaacgca ggatgtaacc
     1381 cagcagacgg taatgactgt acttcaccca tcatcataat ttttctccct gggccaacag
     1441 cgcagcccca agtaaacctg catcatggcg gtaatgcgcc gccagtaaat caacatgaaa
     1501 tgccgctggc tcctgcgcca gatacgtttc caccagcgcc agataccctt ctgccagacc
     1561 aacgctgcca ccgaccacca cgcactggca atcagttgtg gctttaatat cagcgatcag
     1621 ccttgcaagc gtacgtgcgg agcggtgaat cagctgctgc gcctgctcgt caccctgccc
     1681 ggcgcgcgtg aaaatagttt tcgcatccgc gccagccaac tccccctgcg ctgccgctgc
     1741 aatgccgcga ccagaagcaa tcgcttccac gcaacctgtg cgtccacagc cgcagactgg
     1801 gccgtgtgga tcggcaagcg tatgcccgat atgccccgcc agaccgccag ggccggtaag
     1861 cagtttgcag ccgctcacta caccgccgcc aacgccggtg gaaacggtga taaagaccat
     1921 atcggttata tcgccatcca gcgcctgaaa ctccgcccat gctgcggcct gcgcgtcgtt
     1981 aatggcaatg gtcggcaaat tggtaagttg ttccagcgtt ttgactaacg gaaagtgtag
     2041 caatccacca agattatgcg gattaagcgc cagcaagctg ccgtcacgga ttatcccggt
     2101 cgaagcgatg gcaacccgct gcgcatgagc ttgcaacgga gagactaatg cggataaggc
     2161 atcacgcaag gcttctggtg tctggctggc tggcgtagga agttcacgac gatcgcggat
     2221 ctgcccgtca gcgccaatca gcgcggcggc aagtttagta ccgccgatat caatcgccag
     2281 tgtggtcata gcaccgcctt tttcatcgct gtgttgtacc actgacaaat gtgctcaaga
     2341 cgcgtgattg cagaaccgac cgtcaccgcc cacgcgccgt ggcgcatcgc atccgccgcc
     2401 tgagcaggcg tgttgtaacg cccttcggca atcacccgac atccggcgtc gctcaacgtt
     2461 ttcaccagcg ccagatccgg ctcttctggc gtttcaggcg tggtatagcc agaaagcgta
     2521 gtgccaataa tttcggctcc cagcttttgg catgccaggc cgtcttccgg cgttgagcag
     2581 tcggtcatcg ccagtaaacc gtgatggtga atacgtgcca gcagcgtttc aacaggcacc
     2641 ggacgcgggc ggtcggtgcc gtcaatggcg ataatgtccg cgcccgcctg cgccagcgca
     2701 tcaacatctt caatataggc cgtgatgcgt accggagaat cctccagatc gcgtttcaca
     2761 attccaataa tcggcacgct caccaccgca cgcgtggctt gcagatttgc cacaccttca
     2821 atgcgaatgg caaccgcgcc cgcctgttct gccgctaatg ccatcgcggc gacgatttcg
     2881 ggtttatcga gcgggctgtc cggaaccggc tggcaggaga caatcaggcc accgttagca
     2941 gcgatttttt gatccagttg tgcaagtaac gacatacatc ttcccttagc gaaaggcccg
     3001 gtacatagac cgggcaacag gattaacttt tggttttgac taaatcgttt ttggcgctgc
     3061 caaacggcac ggcaccgctg aatggtttac cgtcgatagc gtcatgagta cgcaacgctt
     3121 ccgggcgcaa ccaacgctga acgcgagaag gcatatccag cccaatcagc aggatcacca
     3181 cgaacgtcag actgaacgag agcgatgcca gcgcagtacc cagatccaga cgttgagcga
     3241 tcaacgcgcc gatgattggg gccagtgcac cgcccaatgc gccaacgttg taggtaaagc
     3301 ccaggcccgc tgcacgctgg tcggtatcga aataaccgcc aatcagtttt ggtaagatcc
     3361 cggcgatccc ttgtccaagc atttgctgga agaacagtaa cagaccgagc acccagacgt
     3421 ttgcgccgcc aatcgcaaat accggaataa tcagcagctg cgaggccagc aggctacaaa
     3481 cgtacgcttt gcgggttccc agccagtcac cgaggaagcc acctacgcag catcccaccg
     3541 ccgcgccaaa gccactaaag aacagcacat tggctacagt atgcgggtta taagccagat
     3601 cggttttcag atacgttggc agcagcgcct gaatcggcca tgagtagagg aaagcaaaca
     3661 acacgaccac catcagcatt acgcccgttg gccagcgttt gcctgtactc tgcaccataa
     3721 agctgataaa gattgcggcg cataacagcc caagaacagc gacgatcgcg gcattttgca
     3781 ggttaccggc gaagcagaac cacagcgcag tagccgccgc cagtgtcatt acgatattgg
     3841 caatgcgatg ttcaccacgg tagagaatat ccaccattgt gcgtactggt gctttacctg
     3901 cgtgtttctc tttccagtct tccgcttccg ggatgttttt acgcagccag agagcaaaga
     3961 tgattggcaa aatgccgata aagaacagcg cacgccagcc ccagaccgga accaccaggc
     4021 tatagacctg agcggcaacg acggccccca cagagaagcc tgaaatcaaa aaaccactgg
     4081 ctttgttacg cagatgtttt ggccagcttt caatgacata ggtggcgctg gaaccgtatt
     4141 cacccgccat ccccatgccg atgaccagac gagcgataaa catggtgatg tagcctggcg
     4201 caaagccgca ggccagcgtc ccggccgaga agagaacgat gctggtgacc attgccagac
     4261 gacgcccgta gcggtcaccc atagcgccga gcatcaggcc gccgaaccag cgagagataa
     4321 aggctgcaga gatcagactt gccgcctgca ccgtcgtcag cccgaattca ccttgtactt
     4381 cggtgagtac cagggcgatt aaaacgaaat caaaaccgtc aagcagatat cccaaccagg
     4441 cagcggaaaa tgcgcgccat tgtgcacggt tgagatggcg ataccacggg atattctggg
     4501 ttgtagtact cattgtgagt ctcccgcggt gggcgatgcc cacacgcttt ggtatgaaaa
     4561 ttgtagggta cagatgcgtt tatttcccct cacccggtag gggcgagcga ggggaaacaa
     4621 ctcacccgcg ctcttgcatc aactgctggg ccagcgcctt cagttctggc agatattttt
     4681 catctaccgg tccaaacggt ttgcggcaca gcggcacaga aacgacatcc atataatgga
     4741 ggacagtttt caggccgcgg aatacgcccg ttttgatcag taaatcaatg actttattgc
     4801 attcagtttg cagtttctgc gcggtctgga tatcgccttc tttcagcgcc ttaacgatcc
     4861 cctgatagcg ccagcccatg atgttgtagg tactgccgat accaccatca gcgcccgcca
     4921 gcagaccaga ggcgaagatt tcgtcgtaac cgttatagag cacaagatca ggatgttcac
     4981 gacggatctg ctccatctga tagagatcgc cagaggtctg tttcagcgca cctacgccag
     5041 gcaatgtaac aagtgtgttg atctgatcca gggtcagttt taccccactc agggctggaa
     5101 tgttgtacac caccatcggc aaaccatccg ccgaatcaat aattgcccga tagtgatcgc
     5161 agtgttcttc aaagctgaaa ggatagtaga acggcgtgac ggcggagacg gcatcgaagc
     5221 cataacgttt agccgatgcc gcaagttgtt ggctttcggc ggtgctgacg caaccgacgt
     5281 gggcgatgag tttaatctta cctttcgcct cttcggcgac gatttccagt acctgttcac
     5341 gctcggaaag gctttgtaca aaggcctcgc cggtcgaacc acccacgtat aaaccgtcga
     5401 tgccctgctg aatattgaac tgaaccaggc gacgcagact cgctttatcc agtgcttgtt
     5461 gttggtcaaa aggagtcagg agtgcagcca ttacgccacg taaattcgtt gccataaata
     5521 cctctgaagt gatgcttgtc tgataaacga tataccttta tacctgttat accagatcaa
     5581 ttaagcaaca ccccatacag aaagcttata atgcgatctg cttcactaaa gtggcattat
     5641 ttctttttgt tggtggtctg accgaaagcg tgccaggtag cagagacgct gttgagatgc
     5701 gattgcaacg cacgatcggc ttcgtcagga tcatgacggc ggatcgcatc aacgatcgca
     5761 atatgctgtt gataactaac gttgttatgt tcgtgcagtg cctgatcggt aaccgttggg
     5821 cgtgcggcaa taagccagtc gagcagggca acgtggatcg ccatgaagat tgggttaccg
     5881 gggatctccg ccagcacgcg gtggaaatca acgtctgaac gaatgaatgc cgcgttgtta
     5941 tccagcgact gactgttgat ttccagtgct tttgccagca aatcgatttg ctcatcggtg
     6001 gcatgttcag ccgcatagcg caccagactg gattcaaaga acagacgtaa ttgttcgaaa
     6061 tgggcaatcc caccgggatg agaaaggaaa tctttcgcca tgccggaaag ctcaccgatg
     6121 atagtgtccg cagaaggacg cgagacgcga gcgcgttcgc cgttgtttat ttgcaccaga
     6181 cctttgcgtt ttaacgctgc cagcgcttca cgcaccgaag gacgcccgac gttaaagaac
     6241 gccatcagtt cgcgttcaga cggtaattgt tcaccttcgc caaattcacg acggcggatc
     6301 atctgttcca gctcttcttc caccatttcg gagagttttt tacgcgccag cgggcggcta
     6361 cgcaagttgc gaccaattgc aggtgaagaa tcttcggttt gcgaatcaaa tgcgttcata
     6421 aggcccattc tgtaaggtca gtgtgattaa catcatcagt gacatcctat cacaggattg
     6481 aaagtagggg aaaatggcag ggttttctct ttgtgcctca tcattaccat aattaacgga
     6541 ataattaact attgcgaaaa attaatgtaa cgcagataaa aacatcccgt ttgaattatt
     6601 tataagacta ttcacgagca ttatgaatat tatgaatgtg ttcttacaaa ataatcataa
     6661 gcgcatattt tttaatgaaa aatcacctca cctacaatta aaaacacgac atccgcacca
     6721 taaatagcct tgcaaaaaat ataacatcgt tgttttcaat ctgccgttta tgggattgac
     6781 cgttttcttt tgacacggag ttcaacaatg ttcggcataa ttatatctgt catcgtatta
     6841 attacgatgg gctatttgat cctgaaaaac tacaaacctc aggtggtgct ggctgccgca
     6901 ggtatcttcc tgatgatgtg cggtgtctgg ttagggttcg gtggtgtact cgatcccacc
     6961 aaaagcagcg gctacttgat cgtcgatatt tataatgaaa tcctgcgcat gctgtccaac
     7021 cgcattgccg gattggggct gtcgattatg gcggtgggcg gttatgcccg ctacatggag
     7081 cgcatagggg ccagtcgcgc gatggtgagc ttgttaagcc gcccgttaaa actcattcgc
     7141 tcgccgtata ttattctgtc ggcaacttac gtcatcggcc aaatcatggc gcagtttatt
     7201 accagcgcct ccggtctggg tatgttgctg atggtcacct tatttccgac gctggtgagt
     7261 ctgggagtaa gtcgtctctc tgcggtggca gttatcgcaa ccacgatgtc cattgagtgg
     7321 gggattctgg aaacgaactc catttttgct gcccaggtag cgggaatgaa aattgccaca
     7381 tacttcttcc actaccagct tccggtcgcc tcttgcgtca ttatctcggt ggcgatctcc
     7441 cactttttcg tgcaacgcgc ttttgacaaa aaagataaaa atatcaatca cgaacaggca
     7501 gagcaaaaag ctctcgataa tgtcccgccg ctctattacg ccattttacc tgtgatgccg
     7561 ttaatcctga tgctcggctc gctgttcctc gcccacgtcg ggctgatgca gtcagaactg
     7621 catctggtgg tggtgatgtt actgagtttg actgtgacga tgtttgttga gttcttccgc
     7681 aagcataact tgcgcgaaac aatggacgat gtgcaggcgt tttttgacgg catgggtacg
     7741 cagtttgcca acgtggtaac gctggtggtc gcgggtgaaa tatttgcgaa aggcttaacg
     7801 acgattggca ctgtcgatgc ggttatcagg ggggcggagc attctggtct gggcggtatt
     7861 ggcgtgatga ttattatggc gctggtcatt gccatttgtg ccattgtgat gggctctggc
     7921 aatgcgccgt ttatgtcatt tgccagtctt attccgaata tcgcagccgg actacatgta
     7981 ccagcggttg taatgattat gccgatgcat tttgccacga cgctagcgcg cgcggtttcg
     8041 ccgattactg cggtggtggt cgttacgtca ggaattgcag gcgtttcgcc ttttgcggtg
     8101 gtgaagcgga cagcgatccc catggcagtc ggtttcgtgg tgaatatgat tgccacaatc
     8161 acgctatttt attaagtcat taaaaagaca aaacaggccg cctgggcctg ttttgtatta
     8221 cttcacaacg cgtaatgccg gtcgaccacc gcgtggtggc tgcggaggtt catcgtcagg
     8281 atgagtgtca tcatcgtgat ctggcttgtc gccatcaata accgacataa cggtttcgtt
     8341 gtctgccgat gcctcttcat cattcatgat gctggtatct tcatcgtagg cagcttcagg
     8401 ctcaaacatc gtgcctgcgc cattttcacg ggcgtagata gccagcacgg cagccagcgg
     8461 cacagaaacc tgacgcggaa tgccaccaaa gcgcgcgtta aagcgcacct catcattcgc
     8521 cagttccaga ttgccgacag cacgcggcgc aatgttgagt acgatttgcc cgtcacgcgc
     8581 atattccata ggaacctgca cgccagggag cgtcacatcc accaccaggt gcggcgtgag
     8641 ctggttatcc agcaaccact catagaatgc acgcagcaga tagggacgac gtggtgttag
     8701 ctgtgacaaa tccatacaga ttaactccgg cccagacgca tttcacgttc tgcttcagtt
     8761 aaagaagcaa ggaaagagtc acgctcaaag acgcgggtca tatagccttt cagctctttc
     8821 gcacccgggc cgctgaactc gatgcccagt tgcggcagac gccacagcag cggagcaaga
     8881 tagcaatcga ccaggctgaa ctcatcgctc aggaagtacg gcttctgacc gaagaccggc
     8941 gcaatcgcca gcagttcttc gcgcagttgc ttacgtgcgg catctgcttc agaagctgaa
     9001 ccgttgatga tggtgttcat cagcgtgtac cagtcttttt cgatgcgatg catgtacaga
     9061 cggctttcac cgcgagctac cgggtaaaca ggcatcagtg gcggatgcgg gaaacgctca
     9121 tccagatatt ccataatgat gcgagattcc cacagggtca gctcacgatc caccagggtc
     9181 ggaacgctct gattcgggtt gaggtcaatc agatcctgag gcggattgtc cttttccacg
     9241 tgttcgatct cgaaacttac acctttctca gccagcacaa tgcggacctg atggctatag
     9301 atgtcagtag gaccggaaaa cagcgtcatt accgaacgtt tgttggcagc gacagccatg
     9361 aaaacctcca ggtatagtca gaatttttac tgctaccagc caccaggtgg ccagtcagaa
     9421 gttgtgttac ccaataagga acgactctct ttgttcgaaa atcaaacaaa aaatgagcaa
     9481 tacccgacat ttgggcagaa aattggatga tagtttacca gattttgcga ccattgtggt
     9541 gagtcgatgc cggaaatggg gaaaaagaga tgcgctttag tctgaaatag ttgacttagt
     9601 cccttattgg cgatgtggtt tttgttttac ctgtctgtca ggtggcagca aaaagcaact
     9661 ttccagtttt tacgctgatt cagattttag ctataaaaaa acccgccgaa gcgggttttt
     9721 tcgaaaattg ttttctgccg gagcagaagc caattaacgt ttggagaact gcggacgacg
     9781 acgtgcttta cgcagaccga ctttcttacg ttcaacctga cgagcgtcac gagtaacgaa
     9841 gccagcttta cgcagttcag aacgcaggga ctcgtcgtat tccatcagag cgcgggtgat
     9901 accgtgacgg atcgcaccag cctgaccaga gataccacca cctttaacgg tgatgtacag
     9961 gtccagtttc tcaaccatgt cgaccagttc cagcggctga cgaactacca tgcgggcagt
    10021 ttcacgaccg aagtactgtt ccagagaacg ttggttgatt acgattttac cgttgcccgg
    10081 tttgatgaaa acgcgagctg cggaactttt gcggcgacca gtgccgtagt attgattttc
    10141 agccattgcc tataatcccg attagatgtc aagaacttgc ggttgctgtg ccgcgtggtt
    10201 gtgctcgtta cccgcgtaaa ctttcagttt acggaacata gcacgaccca gcgggccttt
    10261 tggcaacatg cctttaaccg cgatttcaat cacacgctca ggacggcgag caatcatctc
    10321 ttcaaaggtc gcttgtttga taccaccgat gtggccggtg tggtgatagt acactttgtc
    10381 agtacgcttg ttgccggtta cagcaacttt gtcagcgttc agaacgatga tgtaatcacc
    10441 ggtatctacg tgcggagtgt attccgcttt gtgcttaccg cgcaggcgac gagccagttc
    10501 agtagccaga cggcccagag ttttaccggt cgcgtcaaca acataccagt cgcgttttac
    10561 ggtttctggt ttagctgtaa aagttttcat taaaagctta cccaataaat agttacacgt
    10621 tggtgaacac ccaaacgtct tcaattgttg aggttcacac gacaaagtcc ggcaaaccta
    10681 ccccttcgaa tagcctatgc cagcacacaa aaagttttgg gaaaaaaact ttcttgtaac
    10741 gtggggtcgc aggattatag agaagtcggg gtcaaagatc gacccctttt tgtgatttgt
    10801 gacaggtttt aacccgccaa atgctcgcgc ttcagatact cttcgctttg catctcttgc
    10861 agacgtgaca ggcaacgctg gaactcaaac ttcagccgat cgccctgata aatttcatac
    10921 agcggcactt ctgcactcac cactaatttg acatggcgct cgtaaaactc atccaccagc
    10981 gcaataaagc gccgcgcttc gctctccatc aaccgcgtca taactggtac atcaaacaac
    11041 atgaccgtat gaaagagacg tgagagcgca atatagtcat gctgactgcg ggcgtcgacg
    11101 cacagcgtag taaaagagac cgccagcgtc tggttctcga cgcccattgt tgctaatggc
    11161 cgatggttga tttctaacgt cggtgaattt tctcgtttcc cccccgccag cgccaaccat
    11221 agtttatcca tttgcgcccg ggtttcatcg tgaagtggcg aaagccacag atgcgcctga
    11281 gtgagtgtac gcagacgata atcaacacca gcgtccacgt tcattacatc acaatgctgt
    11341 ttaatggcat cgattgcagg cagaaaacgc gcacgttgca ggccatttcg ataaagttca
    11401 tccggcggaa tatttgacgt cgctaccagg gtaataccgc gagcgaacag ggctttcatc
    11461 agaccgccaa gtagcatggc atcggtaata tcagaaacaa aaaattcgtc aaaacagagc
    11521 acgtcagttt cggctttaaa gcgatcggca ataatttcca gcggatcggt ctgcccctgt
    11581 aaggcagtta gctcttcatg cacccgcagc ataaaacggt gaaagtgcag gcgctgtttc
    11641 cgctctcccg gcaggctttg atagaaaagg tccatcagcc aggttttccc gcgtcctaca
    11701 ccgccccaca tatataagcc acgcactggc gtatgctttg tgtcttcgcg tttaccccac
    11761 agcttaccga cccgcgccat tagcccactc gtcctggggg ctggtggcgt gctattgatg
    11821 agttcctgat aaataatttc caggcggctg acggcctctt tttgaacgtc gtcgggttga
    11881 tggctgcctt cattaagcgc cttcaggtat tgcgatgttg gggtaacgct ttgcatgatc
    11941 ttattgttat tccttgaata atcggtgcgc cgttgttcac ggttgacgaa aaaaaggccg
    12001 ttctacacta cgcgatatgc agtcgggatt ccacttctgt ggaattaacg gttatagtgg
    12061 cataatcagc cgcaggcatg gagcctgaag ccaacaccct acggaaacaa aagacaacgg
    12121 gagatgttca tgacctggga atatgcgcta attgggttag tcgtcggcat cattattggt
    12181 gctgtggcca tgcgttttgg taatcgtaaa ctacgccagc aacaggcgtt gcagtacgaa
    12241 ctggaaaaga ataaagctga actggacgag tatcgcgaag agctggttag ccactttgcc
    12301 cgcagcgcgg aattactgga taccatggcg cacgactatc gccagctgta tcagcacatg
    12361 gcaaaaagct ccagcagcct gctgccggaa ctgtctgctg aagcaaaccc gttccgtaat
    12421 cgtctggcag agtctgaagc cagcaacgat caggcaccgg tgcagatgcc tcgcgactat
    12481 tctgaaggcg catccggcct gctgcgtact ggcgcgaagc gcgactaatt tatttttcgg
    12541 gcgcagccat tgcgccctcc tcttctctcc ctccccgact atcatttaat ctggtgtctc
    12601 attgttagcc gtctgaaaat tcaataacat caaactgttt tgaatctctt ttcttatcat
    12661 tcaggtacga gagcaggaat aatgaaaaaa caaacccagc tgttgagtgc attagcgtta
    12721 agtgtcgggt taactctctc ggcgtcattt caggccgtcg cgtcgattcc aggccaggtt
    12781 gccgatcagg cccctctccc cagtctggct ccaatgctgg aaaaagtgct tccggcagtg
    12841 gtgagcgtac gggtggaagg aacggccagt cagggacaga aaatcccgga agaattcaaa
    12901 aagttttttg gtgatgattt accggatcaa cctgcacaac ccttcgaagg tttaggctcc
    12961 ggtgtcatca tcaacgccag taaaggctat gtgctgacca acaaccatgt gattaatcag
    13021 gcacagaaaa tcagtattca gctcaatgat gggcgcgagt ttgatgcaaa actgattggt
    13081 agcgatgacc agagcgatat cgccctgtta caaattcaaa acccgagcaa attaacgcaa
    13141 atcgctattg ccgactccga taaattgcgc gtcggtgatt ttgccgtagc ggtcggtaac
    13201 ccatttggcc ttgggcaaac cgccacctct ggcattgttt ccgcattagg ccgcagcggg
    13261 ttgaatcttg aaggtctgga aaactttatc cagacagatg cttccattaa ccgcggtaac
    13321 tccggcggtg cactattaaa ccttaacggt gagttaattg gcatcaacac tgcaatcctt
    13381 gcgcctggcg gcgggagcgt cgggattgga tttgccatcc ccagtaatat ggcgcgaaca
    13441 ctggcgcagc agcttatcga ctttggtgaa atcaaacgcg gtttgttagg catcaaaggc
    13501 accgagatga gtgccgatat cgccaaagcc ttcaaccttg acgtgcagcg tggcgcgttt
    13561 gtcagcgaag tgttgccagg ttctggctcg gcaaaagcgg gcgtcaaagc gggcgatatt
    13621 attaccagcc tcaacggcaa accgctgaat agctttgctg agttgcgctc tcgtatcgcg
    13681 accaccgagc cgggcacgaa agtgaagctt ggcctgctgc gtaacggcaa accactggaa
    13741 gtagaagtga cgctcgatac cagcacctct tcgtcggcca gcgctgaaat gatcacgcca
    13801 gcgctggaag gtgcaacgtt gagcgatggt cagctaaaag atggcggcaa aggtattaaa
    13861 atcgatgaag ttgtcaaagg aagcccagct gctcaggctg gcttgcaaaa agacgatgtg
    13921 atcattggcg tcaaccgcga tcgggtgaac tcgattgctg aaatgcgtaa agtgctggcg
    13981 gcaaaaccgg ccatcatcgc cctgcaaatt gtacgcggca atgaaagcat ctatctgctg
    14041 atgcgttaat gtcgtaaacc gggcatcagg cttacgtgtg atgtccggtt aactcgtggt
    14101 atgctgctgc cgttcccttt tttaatgacg cctccatcat gtttgtgaag ctcttacgtt
    14161 ccgttgcgat tggattaatt gtcggcgcta ttctgctggt tgccatgcct tcgctgcgca
    14221 gccttaaccc gctttccact ccgcaatttg acagtaccga tgagacgcct gccagctata
    14281 atctggcggt tcgccgcgcc gcgccagcgg tggttaacgt ttacaaccgt ggtttgaaca
    14341 ccaactctca caaccagctt gagatccgca ccctgggatc cggtgtaatc atggatcaac
    14401 gcggttatat catcaccaat aaacacgtca tcaacgacgc cgatcagatc atcgtcgcct
    14461 tacaggatgg acgtgtattt gaagcattgc tggtgggatc tgactctcta accgatctgg
    14521 cggtacttaa aattaatgcc actggcggtt tacctaccat tccaattaat gcacgtcgcg
    14581 taccgcacat tggcgacgta gtactggcga tcggtaaccc gtacaacctc gggcagacca
    14641 ttacccaggg gattattagt gccacgggtc gaatcggtct gaacccgacc gggcggcaaa
    14701 acttcctcca aaccgatgct tccattaacc acggtaactc tggcggcgcg ctggtgaact
    14761 cgctgggcga actgatgggc attaatacgc tgtcgtttga taagagtaac gatggcgaaa
    14821 cgccggaagg tatcggcttt gcgattcctt tccagttagc aaccaaaatt atggataagc
    14881 tgatccgcga tggtcgcgtg atccgcggct acattggtat cggcggacgt gagatcgcac
    14941 cactgcacgc gcagggcggt ggtatagatc aactgcaagg gatcgtggtt aatgaagtgt
    15001 cacctgacgg cccggcggcg aatgcgggta ttcaggtcaa cgatctgatt atttcggtgg
    15061 ataacaaacc ggccatctct gctctggaga cgatggatca ggtggcggaa attcgccctg
    15121 gttcggtgat ccctgtagta gtgatgcgtg atgataagca gttaacgctg caggtcacca
    15181 ttcaggaata tccggcaacc aattaagtcg tgcgctcaaa acaaaaaacc ggagtctgtg
    15241 ctccggtttt ttattatccg ctaatcaatt acttattaac gaactcttcg cccagggcga
    15301 tatctttctt cagcgtatcc agcatacctt ccagcgcgtt ctgttcaaat gcgctcaggg
    15361 taccgataga tttacgctct tccacgccgt ttttacccag cagcagcggt tgagagaaga
    15421 aacgggcgta ctgaccgtcg ccttcaacgt aggcacattc gacaacgcct tgttcgccct
    15481 gcagtgcacg aaccagagac agaccaaaac gtgcagctgc ctggcccata gacagggttg
    15541 cagacccgcc accggccttc gcttcaacca cttcagtacc cgcgttctgg atgcgtttgg
    15601 tcagatcagc cacttcctgc tcggtaaaac taacgccagg aacctgtgac agcagcggca
    15661 gaatggtaac accagagtga ccgccaataa ccggcacttc aacttcgcct ggctgtttgc
    15721 ctttcagttc cgcaacaaag gtgttggaac gaatgatatc cagcgtggta acgccgaaca
    15781 gtttgttttt gtcataaaca ccggcttttt tcagcacttc agcagcaatt gcaactgtgg
    15841 tgttaaccgg gttagtgata ataccaatgc acgctttcgg gcaggttttc gcaacttgct
    15901 gtaccaggtt tttcacgatg ccggcgttaa cgttaaacag gtcggaacga tccatacccg
    15961 gtttacgcgc tacgcctgca gagataagaa cgacatctgc gccttccagc gccggagtcg
    16021 catcttcacc agaaaaacct ttgattttca cagcagtagg gatatggctc agatcgacag
    16081 ccacaccggg agtcactgga gcgatatcat acagagagag ttctgaacct gaaggcagtt
    16141 gggtttttaa cagtagtgca agcgcctggc caataccgcc agcagcgccg aggactgcga
    16201 ctttcatcct aaactcctta ttatattgat aaactaagat atgttgctcc gctgccgcga
    16261 ccttaatcca caaaattgcc gtttacaatg accacatctc aagaatgtgt agtcacgcaa
    16321 gtttagcgtt tatgcattta attgccgtaa tcaggaacct aacttacgta attaacagtc
    16381 gcttatgcat tagcgcaaca ttccaacagg tggtgacaat ataccctacc gttcagccaa
    16441 aacaacatca atttgataac aattaattta cttttaagca gaatttgcat gccgtgacgc
    16501 aggcatgttt ctcaataacg aaatttgata aaatcccgct ctttcataac attatttcag
    16561 ccttcttcag ggctgactgt ttgcataaaa attcatctgt atgcacaata atgttgtatc
    16621 aaccaccata tcgggtgact tatgcgaagc tcggctaagc aagaagaact agttaaagca
    16681 tttaaagcat tacttaaaga agagaaattt agctcccagg gcgaaatcgt cgtcgcgttg
    16741 caggagcaag gctttgacaa tattaatcag tctaaagtct cgcggatgtt gaccaagttt
    16801 ggtgctgtac gtacacgcaa tgccaaaatg gaaatggttt actgcctgcc agctgaactg
    16861 ggtgtaccaa ccacctccag tccattgaag aatctggtgc tggatatcga ctacaacgat
    16921 gcagttgtcg tgattcatac cagccctggc gcggcgcagt taattgctcg cctgctggac
    16981 tcactgggca aagcagaagg tattctgggc accatcgctg gcgatgacac catctttacc
    17041 acccctgcta acggtttcac agtcaaagac ctgtacgaag cgattttaga gctgttcgac
    17101 caggagcttt aatctctgcc ccgtcgtttc tgacggcggg gaaaatgttg cttatccctc
    17161 tcaaccccct gctttcccct gcgattaatt taacgaatag tgcgttttac tgcgacatgt
    17221 cattcacaca atgaatacat aaggtaaaaa aagcacatta tgcaaaattc attatctaat
    17281 tgaaaaaa
//
LOCUS       DACAOP010000094        17149 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.094, whole genome shotgun sequence.
ACCESSION   DACAOP010000094 DACAOP010000000
VERSION     DACAOP010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17149
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.094"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(131..1102)
                     /locus_tag="IT892_003497"
     CDS             complement(131..1102)
                     /locus_tag="IT892_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family plasmid partition
                     protein"
                     /protein_id="HAP3136675.1"
                     /translation="MKRAPVIPKHTLNTQPVGDTSLSTPAAPMVDSLIARVGVMARGN
                     AITLPVCGRDVKFTLEVLRGDSVEKTSRVWSGNERDQELLTEDSLDDLIPSFLLTGQQ
                     TPAFGRRVSGVIEIADGSRRRKAAALTESDYRVLVGELDDEQMAALSRLGNDYRPTSA
                     YERGQRYASRLQNEFAGNISALADAENISRKIITRCINTAKLPKSVVALFSHPGELSA
                     RSGDALQKAFTDKEELLKQQASNLHEQKKAGVIFEAEEVITLLTSVLKTSSASRTSLS
                     SRHQFAPGATVLYKGDKMVLNLDRSRVPTECIEKIEAILKELEKPAP"
     gene            complement(1102..2268)
                     /gene="sopA"
                     /locus_tag="IT892_003498"
     CDS             complement(1102..2268)
                     /gene="sopA"
                     /locus_tag="IT892_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid-partitioning protein SopA"
                     /protein_id="HAP3136676.1"
                     /translation="MKLMETLNQCINAGHEMTKAIAIAQFNDDSPEARKITRRWRIGE
                     AADLVGVSSQAIRDAEKAGRLPHPDMEIRGRVEQRVGYTIEQINHMRDVFGTRLRRAE
                     DVFPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDL
                     HIHAEDTLLPFYLGEKDDVTYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPT
                     DPHLMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQ
                     FFDMLRDLLKNVDLKGFEPDVRILLTKYSNSNGSQSPWMEEQIRDAWGSMVLKNVVRE
                     TDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR"
     gene            complement(2856..3611)
                     /gene="repE"
                     /locus_tag="IT892_003499"
     CDS             complement(2856..3611)
                     /gene="repE"
                     /locus_tag="IT892_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="HAP3136677.1"
                     /translation="MAETAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVD
                     QIRKSDGTLQEHDGICEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYRPEED
                     AGDEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNP
                     YAMRLYESLCQYRKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINS
                     RTPMRLSYIEKKKGRQTTHIVFSFRDITSMTTG"
     gene            complement(4385..5191)
                     /locus_tag="IT892_003500"
     CDS             complement(4385..5191)
                     /locus_tag="IT892_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HAP3136678.1"
                     /translation="MSGSVIHSQSAVMVPAVYSAGQPASLPVAIDYPAALALRQMSMV
                     HDELPKYLLAPEVSALLHYVPDLHRKMLLATLWNTGARINEALALTRGDFSLAPPYPF
                     VQLATLKQRTEKAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNRR
                     TGRTEKARIWEVTDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIP
                     LKVLQSLMGHKSISSTEVYTKVFALDVAARHRVQFAMPESDAVAMLKQLS"
     gene            complement(5192..5497)
                     /gene="ccdB"
                     /locus_tag="IT892_003501"
     CDS             complement(5192..5497)
                     /gene="ccdB"
                     /locus_tag="IT892_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin CcdB"
                     /protein_id="HAP3136679.1"
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSD
                     KVSRELYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     gene            complement(5499..5717)
                     /gene="ccdA"
                     /locus_tag="IT892_003502"
     CDS             complement(5499..5717)
                     /gene="ccdA"
                     /locus_tag="IT892_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin CcdA"
                     /protein_id="HAP3136680.1"
                     /translation="MKQRITVTVDSDSYQLLKAYDVNISGLVSTTMQNEARRLRAERW
                     KAENQEGMAEVARFIEMNGSFADENRDW"
     gene            6351..6548
                     /locus_tag="IT892_003503"
     CDS             6351..6548
                     /locus_tag="IT892_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000215657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136681.1"
                     /translation="MTVFLMAVFYGLLKTGSLIALLVDAYKGWTLFWKNYDRLPHIYR
                     SQWRYQRRFILKRIWKRIRTG"
     gene            complement(6545..6829)
                     /locus_tag="IT892_003504"
     CDS             complement(6545..6829)
                     /locus_tag="IT892_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="korC"
                     /protein_id="HAP3136682.1"
                     /translation="MKAENARQVQGLIELEKFNPETLCSGESWMAPSASEVSVVRALI
                     PLTDIQLANRLDVDERTIRKWKSGETRMVFTTWCCLCWLAGLGMLLEEPA"
     gene            complement(6849..7982)
                     /locus_tag="IT892_003505"
     CDS             complement(6849..7982)
                     /locus_tag="IT892_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001420487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HAP3136683.1"
                     /translation="MHFYVDETGQTGRNLFDKTQPILSYGVLSSEADLDKVAEADLAA
                     LRKTLGVERLHAAELGVHRLSEVVDTLLVLQKNHRIRFDIWQVVKRDHAIISFFDQVF
                     DQGLNPVVPWSAYWTPLRYPLLLNLSNLFDDELAEKAWRARLEAHDERSCSLFSEVCG
                     VLLQRVHSLGDARSVELITDALSWAMVNFDELGYNCKTNKEKLQIMPNMIGFQSVLHG
                     ICSRLGAPNRKADIIVDQQSQFNTTQRELNEFYYQIREQPWALGPGLPVMDMKNMPAK
                     PLVFQSGTMSAGLELVDIYLWIFKRYMERKELTKPLSRLVYTNLKTARTDSVSLQSVA
                     KRFKEFFEKLSEPTAEMIEKANELRAVEETRRLAHRVQSVSQS"
     gene            complement(8245..11364)
                     /locus_tag="IT892_003506"
     CDS             complement(8245..11364)
                     /locus_tag="IT892_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000467135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136684.1"
                     /translation="MFGKLLKSVSWQVRAELRRSLKSNRDYKKLRWNPVERILVSCST
                     HYVRAMLVLWSAAFGAVGVVEYFRPVLLPFAVQHFKGITKLSDWMSNLLGSQLTIIGI
                     VFPLVVGLISVLFQKKSARIHIQSAYQLHSGYMFAGLSGLSLAAFVVLGGMTLSIGDG
                     YLNTSFAVTAFVWMLFNIILSIWFFVSSLNVLDESKRDRLMNKFFLSQIVDDYIQKAY
                     IQAWLRYPGGHVGQNYLGNIKILPYSISEKDDMLHVKSNISKGDVVTDIYIRPFLFLL
                     RRLEAVDGQDAEIIILPSFGVRSGELTLLSSRNVKPVSGLWRWLLRRCIVTGRPENKR
                     DLDDITFDFFGEAYDALNDKNISVFRTGIERLTDTYTSIKRSYNYEVDKNYLDEVKES
                     GFSHTFSDSFHYELRKFFRESVKSTEYSGEYFRESMLIPLRVYRKTQSTCFTDFRQFL
                     LSLFRVWHVLNEWKAGLGGPLSASQELTHQALIRGYIGLWEGWSMTTITGKPGSEDST
                     GRLMYHLHNTARLLIPSVVADNASSVRYAHDVLCLWFNQSRFTRYWEEEYRWHSFFLT
                     PDYLSLKETEPQWNMLLRGSKYKKDAALSIMFANALSDLRLLMAGYLIAHFESQKNID
                     LADLVNHLIMSELYEDRDTHDTLTPAFRRSVDIIDMILRIEHCNLHTNTSWYSGLSET
                     IEVMNSYNERPYIPGRMYTGEYEDLGSLYGSFALLAIKLARPAEQVTQRVNEALAGGV
                     FSYSSKDRIISILKRLKRDPSVPYEGYIISEADYATNVVFFNDVLDKYIDVFSRSKTA
                     DIVAAEVDQARLRNTDARLTNELPGALSEDVLLKYFTFTQNSECDRNWLAIYIPVGVS
                     KEYVARELNQTDYGDFPSVSEVNRNILRRLHYVLWQSQAKLTIEVNNLETLLMEVAQR
                     SADQNNYILVIYGSRFSEELRELVYQPERHDAFSIHVDVSARGSRSLPFRINNCLIYL
                     VLNSEQEFSLMVSAESFGELRLFRYPDGTLFNTFYRSSDDPLEGVMKTLWEIEMEITD
                     TPVARFEHR"
     gene            11671..11901
                     /locus_tag="IT892_003507"
     CDS             11671..11901
                     /locus_tag="IT892_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HAP3136685.1"
                     /translation="MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVR
                     PTWGSFLEYEKADPDFMAEREDVVSDEGRFNL"
     gene            11898..12314
                     /locus_tag="IT892_003508"
     CDS             11898..12314
                     /locus_tag="IT892_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HAP3136686.1"
                     /translation="MNKTYMLDTCICSFIMREQPEAVLKRLEQAVLRGHRIVVSAITY
                     SEMRFGATGPKASPRHVQLVDEFCARLDAILPWDRAAVDATTKIKVALRLAGTPIGPN
                     DTAIAGHAIAAGAILVTNNTREFERVPDLVLEDWVK"
     gene            complement(12476..14614)
                     /locus_tag="IT892_003509"
     CDS             complement(12476..14614)
                     /locus_tag="IT892_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000350616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP3136687.1"
                     /translation="MDIEIRHCNNIVRAHITLTADKLNIKFAPNGTGKSTLSRAISCA
                     ARDDIQGLQALMPFRLRGENPDSTGPIVIGADGIGDVMCFNEEYVSQFTFQPDELISD
                     SFNILIRNQAHAEREREIEEMTQKIRAVFTDHTELNSLIDHLQELSNAFKSTSSGISR
                     SSTGMRGLSGGNKIHHIPAGLENYQPYIRSERRVEWIDWQTKGLEFSPLSDGCCPFCT
                     GDITGKEAQIRQVREEYDKSTIKNLTAIIRLVENLGNYLTESARERLLAITMLQNGPE
                     AEHIEYLVALKRQTDTLTEKLTALRGLNVFSLQEQQNVREVLTARLIDLQFFPDLQSE
                     LMQGITDRLNAALMDLINLAGPLQGKINRHRDSMIRLIAQHKTNINNFLTYAGYKYRV
                     DIAGEGEQRKLRLRHIDFDGYVSGGSQHLSYGERNAFAIVLFMYECLSKNPGLIILDD
                     PISSFDKNKKFAILEMLFRRASGECLKNRTVLMLTHDVEPVIDTLKSVRRLFSNQVTA
                     SCLRLSAGVIEELPVNDGDIMTFMQICKSITASADCEEIIKLIYLRRYFEIVDERGDA
                     YQLLSNLFHRRVAPLDYREPAAAGSGYPKMAPEKIQQALRDIREYVDSFDYPRLQALV
                     SSPDEIKNLYRRCRNGYEKLQVFRLLELDQDHPVIRKFVNETYHIENEFICQLDPSRF
                     DLIPEYVIMECDKLIALPPAANQSSVARIA"
     gene            15079..16074
                     /locus_tag="IT892_003510"
     CDS             15079..16074
                     /locus_tag="IT892_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013578371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAP3136688.1"
                     /translation="MATTVIAAFNEFMKDTVNLKKADTDDARASRDWLIGKMNDFEKD
                     DKFPVSFPAIHIAFGSFARRTKIRPLDDIDLMFGLTGQGATYTILSDRITVTSSGEGS
                     RLHSYRHSGADTVCSVRILNAFKNRLQDIAQYAQADIRRNQEAVTLKLVSKDWNFDIV
                     PCFITSEDAFGRTYYLIPDGNGHWKFTDPRKDRDRVTTINVQNNGNVLNVIRAVKYWQ
                     RRPTMPSMSSYLLETLILDYYAGRTSCSSFVDMELEALFRHLGQSVRYSVNDPKGIQG
                     DINSLSAEARKAISDRCYLDAQKVSEARWFENNKEYEKSINKWRDVFGPFFPVYG"
     gene            16078..17010
                     /locus_tag="IT892_003511"
     CDS             16078..17010
                     /locus_tag="IT892_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015572052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136689.1"
                     /translation="MNAIYTNQSTRENMDLLYAQARVYDRVKNWNRLNFLFSIIVPLL
                     LSFVTVYNRSREFVDSELLSSLLGLYGLLVLTFNIVISGHISALRRKAASIQEMYDCR
                     VLGIRRNELKVEEIPRDDIIREAAYFRDSPEKARKRFGEEGWYVSKVYDAPQAVMALL
                     CHGKNLGWDKSLREVLHVFYLSAFIVSPVAMLVYGIVMKSGLNEILFYVVFTLPVIRY
                     FLLQFLDNRSSMKRSEKLKKHVEKELSGIRVSGRAEEEQLAYTLRNIQDEMFTYRASC
                     PPVPNGIQLIMKPKNERIYVDYFETNLKELHLQK"
BASE COUNT         4646 a         4205 c         3913 g         4385 t
ORIGIN      
        1 ctgattatca gaccgacgat acaagtggaa cagtgggccc agagagaata ttcaggccag
       61 ttatgctttc tggcctgtaa caaaggacat taagtaaaga cagataaacg tagactaaaa
      121 cgtggtcgca tcagggtgct ggcttttcaa gttccttaag aatggcctca attttctcta
      181 tacactcagt tggaacacga gacctgtcca ggttaagcac cattttatcg cccttataca
      241 atactgtcgc tccaggagca aactgatgtc gtgagcttaa actagttctt gatgcagatg
      301 acgttttaag cacagaagtt aaaagagtga taacttcttc agcttcaaat atcaccccag
      361 cttttttctg ctcatgaagg ttagatgcct gctgcttaag taattcctct ttatctgtaa
      421 aggctttttg aagtgcatca cctgaccggg cagatagttc accggggtga gaaaaaagag
      481 caacaactga tttaggcaat ttggctgtgt tgatacagcg ggtaataatc ttacgtgaaa
      541 tattttccgc atcagccagc gcagaaatat ttccagcaaa ttcattctgc aatcggcttg
      601 cataacgctg accacgttca taagcacttg ttgggcgata atcgttaccc aatctggata
      661 atgcagccat ctgctcatca tccagctcgc caaccagaac acgataatca ctttcggtaa
      721 gtgcagcagc tttacgacgg cgactcccat cggcaatttc tatgacacca gatactcttc
      781 gaccgaacgc cggtgtctgt tgaccagtca gtagaaaaga agggatgaga tcatccagtg
      841 agtcctcagt aagcagctcc tggtcacgtt cattacctga ccatacccga gaggtcttct
      901 caacactatc accccggagc acttcaagag taaacttcac atcccgacca catacaggca
      961 aagtaatggc attaccgcga gccattactc ctacgcgcgc aattaacgaa tccaccatcg
     1021 gggcagctgg tgtcgataac gaagtatctc caaccggttg agtattgagc gtatgttttg
     1081 gaataacagg cgcacgcttc attatctaat ctcccagcgt ggtttaatca gacgatcgaa
     1141 aatttcattg cagacaggtt cccaaataga aagagcattt ctccaggcac cagttgaaga
     1201 gcgttgatca atggcctgtt caaaaacagt tctcatccgg atctgacctt taccaacttc
     1261 atccgtttca cgtacaacat tttttagaac catgcttccc caggcatccc gaatttgctc
     1321 ctccatccac ggggactgag agccattact attgctgtat ttggtaagca aaatacgtac
     1381 atcaggctcg aaccctttaa gatcaacgtt cttgagcaga tcacgaagca tatcgaaaaa
     1441 ctgcagtgcg gaggtgtagt caaacaactc agcaggcgtg ggaacaatca gcacatcagc
     1501 agcacatacg acattaatcg tgccgatacc caggttaggc gcgctgtcaa taactatgac
     1561 atcatagtca tgagcaacag tttcaatggc cagtcggagc atcaggtgtg gatcggtggg
     1621 cagtttacct tcatcaaatt tgcccattaa ctcagtttca atacggtgca gagccagaca
     1681 ggaaggaata atgtcaagcc caggccagca agtgggcttt attgcataag tgacatcgtc
     1741 cttttcccca agatagaaag gcaggagagt gtcttctgca tgaatatgaa gatctggtac
     1801 ccatccgtga tacattgagg ctgttccctg ggggtcgtta ccttccacga gcaaaacacg
     1861 tagccccttc agagccagat cctgagcaag atgaacagaa actgaggttt tgtaaacgcc
     1921 acctttatgg gcagcaaccc cgatcaccgg tggaaatacg tcttcagcac gtcgcaatcg
     1981 cgtaccaaac acatcacgca tatgattaat ttgttcaatt gtataaccaa cacgttgctc
     2041 aacccgtcct cgaatttcca tatccgggtg cggtagtcgc cctgctttct cggcatctct
     2101 gatagcctga gaagaaaccc caactaaatc cgctgcttca cctattctcc agcgccgggt
     2161 tattttcctc gcttccgggc tgtcatcatt aaactgtgca atggcgatag ccttcgtcat
     2221 ttcatgacca gcgtttatgc actggttaag tgtttccatg agtttcattc tgaacatcct
     2281 ttaatcattg ctttgcgttt ttttattaaa tcttgcaatt tactgcaaag caacaacaaa
     2341 atcgcaaagt catcaaaaaa ccgcaaagtt gtttaaaata agagcaacac tacaaaagga
     2401 gataagaaga gcacatacct cagtcactta ttatcactag cgctcgccgc agccgtgtaa
     2461 ccgagcatag cgagcgaact ggcgaggaag caaagaagaa ctgttctgtc agatagctct
     2521 tacgctcagc gcaagaagaa atatccaccg tgggaaaaac tccaggtaga ggtacacacg
     2581 cggatagcca attcagagta ataaactgtg ataatcaacc ctcatcaatg atgacgaact
     2641 aacccccgat atcaggtcac atgacgaagg gaaagagaag gaaatcaact gtgacaaact
     2701 gccctcaaat ttggcttcct taaaaattac agttcaaaaa gtatgagaaa atccatgcag
     2761 gctgaaggaa acagcaaaac tgtgacaaat taccctcagt aggtcagaac aaatgtgacg
     2821 aaccaccctc aaatctgtga cagataaccc tcagactatc ctgtcgtcat ggaagtgata
     2881 tcgcggaagg aaaatacgat atgagtcgtc tggcggcctt tctttttctc aatgtatgag
     2941 aggcgcattg gagttctgct gttgatctca ttaacacaga cctgcaggaa gcggcggcgg
     3001 aagtcaggca tacgctggta actttgaggc agctggtaac gctctatgat ccagtcgatt
     3061 ttcagagaga cgatgcctga gccatccggc ttacgatact gacacaggga ttcgtataaa
     3121 cgcatggcat acggattggt gatttctttt gtttcactaa gccgaaactg cgtaaaccgg
     3181 ttctgtaacc cgataaagaa gggaatgaga tatgggttga tatgtacact gtaaagccct
     3241 ctggatggac tgtgcgcacg tttgataaac cagggaaaag attcatagcc tttttcatcg
     3301 ccggcatcct cttcagggcg ataaaaaacc acttccttcc ccgcgaaact cttcaatgcc
     3361 tgccgtatat ccttactggc ttccgcagag gtcaatccga atatttcagc atatttagca
     3421 acatggatct cgcagatacc gtcatgttcc tgtagggtgc catcagattt tctgatctgg
     3481 tcaacgaaca gatacagcat acgtttttga tcccgggaga gactatatgc cgcctcagtg
     3541 aggtcgtttg actggacgat tcgcgggcta tttttacgtt tcttgtgatt gataaccgct
     3601 gtttccgcca tgacagatcc atgtgaagtg tgacaagttt ttagattgtc acactaaata
     3661 aaaaagagtc aataagcagg gataactttg tgaaaaaaca gcttcttctg agggcaatct
     3721 gtcacagggt taagggcaat ttgtcacaga caggactgtc atttgagggt aatttgtcac
     3781 actgaaaggg caatttgtca caacaccttc tctagaacca gcatggataa aggcctacaa
     3841 ggcgctctaa aaaagaagat ctaaaaacta taaaaaaaat aattataaaa atatccccgt
     3901 ggataagtgg ataaccccaa gggaagtttt ttcaggcatc gtgtgtaagc agaatatata
     3961 agtgctgttc cctggtgctt cctcgctcac tcgagggctt cgccctgtcg ctcgactgcg
     4021 gcgagcacta ctggctgtaa aaggacagac cacatcatgg tgctgtgttc attaggttgt
     4081 tctgtccatt gctgacataa tccgctccac ttcaacgtaa caccgcacga agatttctat
     4141 tgttcctgaa ggcatattca aatcgttttc gttaccgctt gcaggcatca tgacagaaca
     4201 ctacttccta taaacgctac acaggctcct gagattaata atgcggatct ctacgataat
     4261 gggagatttt cccgactgtt tcgttcgctt ctcagtggat aacagccagc ttctctgttt
     4321 aacagacaaa aacagcatat ccactcagtt ccacatttcc atataaaggc caaggcattt
     4381 attctcagga taattgtttc agcatcgcaa ccgcatcaga ctccggcatc gcaaactgca
     4441 cccggtgccg ggcagccaca tccagcgcaa aaaccttcgt gtagacttcc gttgaactga
     4501 tggacttatg tcccatcagg ctttgcagaa ctttcagcgg tataccggca tacagcatgt
     4561 gcatcgcata ggaatggcgg aacgtatgtg gtgtgaccgg aacagagaac gtcacaccgt
     4621 cagcagcagc ggcggcaacc gcctccccaa tccaggtcct gaccgttctg tccgtcactt
     4681 cccagatccg cgctttctct gtccttcctg tgcgacggtt acgccgctcc atgggtattt
     4741 tcagtgttgc caccatcgtc tgcagctggc tgacgtacca ggagtcagag agcggaacca
     4801 gccggtgagt ctgctgaccg gcgggcattc tccccgccgt cctggcagct ttttcggtcc
     4861 gttgtttcag ggtcgcaagc tgcacaaacg gatacggagg cgcaagcgaa aaatcccccc
     4921 gcgtcagcgc cagtgcttca ttaatgcgtg ctccggtgtt ccacagtgtg gccagcagca
     4981 tcttgcggtg cagatccggg acgtaatgga gcagggcact cacttccgga gccagcagat
     5041 attttggcag ttcatcatgg accatcgaca tctggcgaag tgccagagct gccggataat
     5101 caatggcaac aggcagcgat gcaggctgcc cggcagaata cactgccggt accatgactg
     5161 cagactggct gtgtataacg gagcctgaca tttatattcc ccagaacatc aggttaatgg
     5221 cgtttttgat gtcattttcg cggtggctga gatcagccac ttcttccccg ataacggaga
     5281 ccggcacact ggccatatcg gtggtcatca tgcgccagct ttcatccccg atatgcacca
     5341 ccgggtaaag ttcacgggag actttatctg acagcagacg tgcactggcc agggggatca
     5401 ccatccgtcg cccgggcgtg tcaataatat cactctgtac atccacaaac agacgataac
     5461 ggctctctct tttataggtg taaaccttaa actgcatttc accagtccct gttctcgtca
     5521 gcaaaagagc cgttcatttc aataaaccgg gcgacctcag ccatcccttc ctgattttcc
     5581 gctttccagc gttcggcacg cagacgacgg gcttcattct gcatggttgt gcttaccaga
     5641 ccggagatat tgacatcata tgccttgagc aactgatagc tgtcgctgtc aactgtcact
     5701 gtaatacgct gcttcatagc acacctcttt ttgacatact tcgggtatac atatcagtat
     5761 atattcttat gccgcaaaaa tcagcgcgca aatacgcata ctgctatctg gcttttagta
     5821 agccttatgt attttacctt tcgttatgtt aaccaataaa aattaaaatc tgacttataa
     5881 aaacaaagcg taattaccgc attcccgttt cgtatggatc cgactttatt tgaataaacg
     5941 actttccgga agtgtacaac gctgagaaaa tcatcatatc gctgttttcc gcccctgcac
     6001 ggcgcatcac aggtcaggga aataacacaa catatagtgt catcagcagc tgaatccggc
     6061 accacatgtt gtgcttacag gaagtggcgt tgtgtggggg ggagaggaag atccgtaact
     6121 gccggaaacc ggatctcaga agagaaaaag aagagttgtt gcaagataag cacaaaaaat
     6181 ggtggtttgt tgagatatgg taattattgc tcagtgggca aaattcagaa cagagttagc
     6241 ctgaaattgc aaaaaacagg ccagaaaaac ttttttcagc tcattttcat caaccggcct
     6301 taaaggctgc ttcggatttc ctaaatacag ttttacataa ggaacatcgt atgactgtat
     6361 ttctcatggc cgttttctat ggcctcttaa aaactggctc tctcattgcc ctacttgttg
     6421 atgcctataa aggctggacc ttgttctgga agaactatga tcgactcccc catatctacc
     6481 gttcgcaatg gcgatatcag cgacgcttca ttctcaaaag aatctggaaa cgcatcagaa
     6541 ccggctaagc cggttcttcc agcagcatcc ccaacccggc cagccagcac agacagcacc
     6601 aggtggtgaa caccattctg gtctcgccgg atttccactt acggatggtg cgctcgtcca
     6661 catctagccg gttggccagc tggatatctg tgagcgggat cagcgcccgg accacgctga
     6721 cttcactggc tgaaggtgcc atccagctct cgcccgagca cagtgtttca gggttaaatt
     6781 tctctagttc tatcagcccc tgaacctgac gggcattttc tgccttcata tgcggttaac
     6841 ctttctgatc aggattgcga cacactttgt acacgatggg caagacggcg cgtttcttcc
     6901 acggccctga gttcatttgc tttttctatc atttctgcgg ttggttcaga aagtttttca
     6961 aaaaactcct taaacctctt tgcaactgac tgcagagaaa cactgtcagt tctcgctgtt
     7021 ttaagattgg tgtagacgag gcgggaaagg ggtttggtca gttccttccg ttccatgtat
     7081 cgtttgaaga tccagagata aatatcaacc agttccagcc cggcactcat cgttcccgac
     7141 tggaagacaa gcggttttgc tggcatgttc ttcatatcca tgacaggcaa acccggcccc
     7201 agtgcccacg gctgttcgcg gatctggtag taaaactcgt tcaactcccg ctgggtggtg
     7261 ttgaactgtg actgctggtc aacaatgata tctgctttcc ggttcggagc ccccagacga
     7321 gagcagatcc cgtgcaaaac ggactgaaaa ccaatcatat tgggcatgat ctgcaacttt
     7381 tccttattgg ttttgcagtt gtaccccagc tcatcaaagt tgaccatcgc ccaagatagg
     7441 gcatcggtaa tgagttcaac tgaacgggca tcacccagag agtgaacgcg ctgaagcagc
     7501 actccacaaa cctcactgaa taatgagcaa gaacgttcat catgagcctc aagacgggca
     7561 cgccacgctt tttcagccag ctcatcatca aacagattag acagattcag cagcagggga
     7621 tagcgcagag gggtccagta ggcactccag ggcacaaccg gattcagtcc ctgatcaaac
     7681 acctggtcga agaacgaaat aatggcgtga tcgcgcttaa ccacctgcca gatatcaaac
     7741 cgtatccggt gatttttctg caggaccagc agcgtatcca caacttctga aaggcggtgc
     7801 acgcccagtt ccgcagcgtg caggcgctcc acgcccagag ttttgcgtaa tgcggcaaga
     7861 tccgcttcag caaccttatc taggtcagcc tctgaggaca gtactccgta ggagaggatt
     7921 ggctgggttt tgtcaaaaag gtttcggcca gtctggcctg tttcatccac ataaaagtgc
     7981 attcagatat ccttttcaag gcaggaggaa aagaaacggc ataattcaaa tcaatgtaaa
     8041 accttcctgt tgccggctgc aagtgatcct cttaaatgag ttttcggatc taaggaagag
     8101 agaagaggga ttattgtatg aatggcacaa aaagcgacgg attgttgcgg tgaatagatt
     8161 attgcttagg aagcaaaatt tatagtaatt gataactcta atgcaattaa acagcgaccc
     8221 catcaggggt caccgtaatt ttgatcagcg atgttcaaac cgcgccactg gagtatcagt
     8281 gatttccatc tctatttccc agagcgtttt catcacacct tcaagtggat cgtcgctgct
     8341 gcggtagaag gtattgaaaa gggttccatc cggatacctg aacagcctga gttcaccaaa
     8401 ggattcagca ctgaccataa gcgaaaactc ctgttcggaa ttgaggacaa ggtaaataag
     8461 acagttattg atcctgaagg gcagagagcg gctacccctg gccgatacat caacatgtat
     8521 gctaaacgcg tcatgccttt ccggctgata gaccagttcc ctcagttcct cgctgaagcg
     8581 ggaaccatag atcaccagaa tgtagttatt ctgatcagcg gaccgttgcg cgacttccat
     8641 taacagcgtt tcgaggttat tgacctcaat cgttaattta gcctgtgact gccacagtac
     8701 ataatgcagt ctgcggagaa tatttctgtt cacttctgat accgaaggga aatctccgta
     8761 gtcagtctga ttaagctctc tggcaacata ctctttggaa acaccaacag gaatatatat
     8821 cgccagccag ttgcgatcac attctgaatt ttgagtaaac gtgaagtatt taagcagaac
     8881 atcttcagac aatgccccag gaagttcatt tgtaagacga gcatcagtgt ttctcagtcg
     8941 agcctggtct acttcagcag caacgatatc tgccgtttta ctacgactga atacatctat
     9001 gtatttatcc agaacatcat taaagaacac cacattcgtt gcataatccg cttctgaaat
     9061 gatataacct tcatagggaa ctgaagggtc tcgtttcagt cgtttaagaa tagaaattat
     9121 tctgtcttta ctggaatagg aaaacacccc tccagccagg gcttcattaa cacgctgtgt
     9181 aacctgctcc gcaggccttg cgagctttat agccagcaag gcaaacgacc cgtagagact
     9241 ccctaaatct tcatattccc ctgtatacat acgcccggga atgtaaggcc tttcattata
     9301 tgagttcata acctcaatgg tttctgataa cccgctgtac cagcttgtat tcgtatgcag
     9361 attgcagtgc tcaattctca gtatcatgtc aatgatatcg acagaacgtc tgaatgcagg
     9421 cgtcagcgtg tcatgtgtat ctctatcttc atataattca gacataatga gatgattcac
     9481 aagatcggct aagtctatat ttttttgcga ttcaaaatga gcaataagat accctgccat
     9541 taacaaccgc aaatcggata aggcatttgc aaacataatg gacaaagcgg catctttttt
     9601 atacttgctg cccctgagta acatattcca ctgcggttct gtctccttca gggacagata
     9661 atccggagtc aggaagaaac tgtgccagcg gtactcttcc tcccagtaac gtgtaaaccg
     9721 gctctgatta aaccagaggc agagaacgtc gtgagcatat cgcacggaag aggcattatc
     9781 ggcaaccact gacggaataa gaagcctggc ggtattatgc agatgataca tcaggcggcc
     9841 agtagaatct tcactcccgg gtttgccagt gatcgtggtc atactccagc cttcccacag
     9901 tccgatatac ccgcggataa gggcctggtg agtcagctcc tggctggccg agagggggcc
     9961 ccccagtccc gctttccact cgtttaacac atgccacacc ctgaaaagcg agagtaaaaa
    10021 ctgtctgaaa tcggtaaaac acgtgctctg tgtttttctg tacacacgca atggaatgag
    10081 catcgattca cggaaatatt cgcctgaata ttccgttgat tttacggatt cacgaaaaaa
    10141 ctttctcaat tcataatgga atgaatcgct gaaagtatgg ctaaaacctg attcttttac
    10201 ttcatccaga taatttttat cgacctcgta attgtaactt cttttgatag aggtataggt
    10261 atctgttaat cgttcaatcc ctgttctgaa gacgctaata tttttatcgt taagcgcatc
    10321 gtaagcctca ccaaagaaat caaaagtaat atcatccaga tcccttttgt tctcagggcg
    10381 ccctgttaca atacaacgac gcaataacca ccgccacaat cctgaaacag gcttgacatt
    10441 tctcgatgac aataaagtca gttcaccaga acgaacacca aaggagggca gaatgataat
    10501 ttccgcatcc tgcccatcta ccgcctctag ccttctcagt aggaataaaa aaggccttat
    10561 ataaatatca gtaacaacat cacctttact gatattagat ttaacatgaa gcatatcgtc
    10621 tttctcagaa attgagtaag gcagtatttt aatattaccg aggtaatttt gacctacatg
    10681 accccccggg taacgcagcc acgcctgaat atatgctttt tgaatgtagt catccactat
    10741 ctgagataaa aaaaacttat tcattagtcg atcgcgtttg ctctcatcca ggacattcag
    10801 actggagacg aagaaccaga tagacagaat aatattgaaa agcatccaca caaaagctgt
    10861 tacggcaaaa gaagtattaa gatatccgtc acctatagat aacgtcatac cgcccagcac
    10921 gacaaatgca gccagtgaaa gaccactcag gcccgcaaac atatatccgg aatgaagttg
    10981 atacgcggac tgaatatgga tccttgctga tttcttttga aataaaacac ttataagccc
    11041 cacaaccagc ggaaatacaa taccgattat agtcaactgg ctacccagta aattagacat
    11101 ccaatctgaa agcttggtaa tgcccttaaa atgctgcaca gcgaaaggta gcaatacagg
    11161 gcgaaaatat tcgaccacgc caacagcccc gaaggctgcg gaccatagaa ccagcatagc
    11221 ccggacgtaa tgggtggagc aggaaacaag tattctctcc accgggttcc agcgaagttt
    11281 tttgtaatcc cggttcgact tcaggctccg tcggagttca gctctcacct gccatgagac
    11341 acttttcaga agttttccaa acatagatat cctgcgtatt acataagaaa ttttatgaat
    11401 aataagcggt aggaaccttt ttttctctgg aaaatgtcac ccgataccct tcatacaggc
    11461 tttgtcatcc taaaatccgg tttaaccttt tttcggatct ccgataaaaa agaaagaaat
    11521 agagatatgc ataaacatat gcctggcatc tacatatgct accgctatac atatgccaca
    11581 catctgccta tactaaacat atgcacacac ccggtgcttt gaatattccg gatatgtttc
    11641 acatatccat atgctcggga gagaaagaac atgagaaccg tatcgatatt taaaaatggc
    11701 aacaaccgcg ccatccgtct gcctcgtgat ctggattttg agggggtgag cgagctcgag
    11761 atcgtccggg aaggggacag catcatcctg cgccccgtcc ggccaacctg gggatcattc
    11821 ctagagtacg aaaaagccga tccagatttt atggcggagc gcgaggatgt tgtcagcgac
    11881 gaagggcgat ttaacctgtg aacaagactt atatgcttga tacctgtatc tgctcgttca
    11941 tcatgcgtga acagccagaa gccgtcctga agcgtctgga gcaggcggtg ctacgcggcc
    12001 accgtatagt ggtctcggcc atcacctact ctgaaatgcg cttcggggct accggcccaa
    12061 aggcctcacc acgtcacgtc caactggtcg atgaattctg cgcccgcctc gatgccatcc
    12121 tgccctggga tcgcgccgca gtagacgcca ccacgaagat taaagtggca ctgcggctgg
    12181 ccgggacgcc gatcggcccg aacgacacgg cgattgccgg gcacgccatc gccgccgggg
    12241 cgatactggt aacgaataat acaagagaat ttgagcgagt gcctgacctg gtgctggaag
    12301 actgggtgaa gtaagacact cttttcaaag tcaggagata agggcaccaa gaaacagccc
    12361 gtatacgggc tgttttaaca gatatctaca gtaagcggtc ctaaactgta gggtatcttc
    12421 gaagatcaga ctatcaggga gctaaagcct atcttccggc ggcaaaaaca gtggctcaag
    12481 cgatacgggc aaccgagctc tggtttgctg ccggtggcag ggcgatgagc ttgtcacatt
    12541 ccataatcac gtactccggg atgagatcga atctggacgg atctagttga cagatgaact
    12601 cattttcaat gtggtacgtt tcgttaacga attttcgtat taccggatgg tcctgatcca
    12661 gttccagtaa acggaatacc tgcagttttt catagccgtt acgacagcga cggtacaagt
    12721 tttttatttc atctgggctg ctgacgagag cctgaagtcg cgggtaatca aaactgtcca
    12781 catactcccg gatatcccgc aaggcctgct gaattttctc aggagccatt ttgggatagc
    12841 ccgagcccgc agcggcaggc tcgcgataat ccagcggggc gacgcgtcga tggaatagat
    12901 tggatagaag ctgataagca tcaccacgtt cgtcaacgat ttcaaagtag cgacgaagat
    12961 agatgagctt aatgatctcc tcacagtctg ctgacgcggt gatggatttg cagatctgca
    13021 tgaatgtcat gatatcgccg tcgttaacag gtaattcttc tatgactcca gcagacaggc
    13081 gcaggcagga ggcggtcacc tgattactga acaaccttct gactgacttc agcgtgtcaa
    13141 tcacaggctc cacgtcatgc gtcagcataa gtacagtccg gttcttcagg cattcaccac
    13201 ttgcacgtct gaacagcatt tcaagaatgg caaacttctt gtttttatca aaagaagata
    13261 tgggatcatc aaggataatc agtcccgggt tttttgacag gcattcatac atgaataaca
    13321 caatcgcaaa ggcgttccgt tctccatagc tgagatgctg gctaccgccg ctgacgtacc
    13381 cgtcaaaatc tatgtgtcgt agcctgagtt ttctctgctc tccctcgccg gctatatcca
    13441 ccctgtattt atagcctgca taagtgagga aattattgat gtttgttttg tgctgtgcga
    13501 tcagccggat catgctgtcc cggtgccggt taatttttcc ctgcagcggt ccggcaaggt
    13561 ttatcaggtc cataagggcc gcgttcagtc tgtcggtgat cccctgcatg agttcggatt
    13621 gcagatcagg gaagaactgc aggtcaatca acctggcagt gagcacctcc cgaacgttct
    13681 gctgttcctg caggctgaaa acattcaggc ctctcagcgc agtgagtttc tctgtcagcg
    13741 tatcggtctg gcgtttcaac gccactaggt actcgatatg ttcggcttcc ggaccgttct
    13801 gaagcatagt aatggccaga aggcgttctc tggcgctctc cgtcaggtaa ttaccgaggt
    13861 tttccaccag tctgatgata gcggtcaggt ttttaatggt ggatttatcg tattcctctc
    13921 tgacttggcg aatttgtgct tcctttcccg tgatatcacc ggtacagaac ggacagcagc
    13981 catccgaaag gggcgaaaac tcgagtccct ttgtctgcca gtcaatccat tccacgcggc
    14041 gttcactgcg gatgtagggt tgatagttct caagaccagc cggaatgtgg tgtattttat
    14101 ttccgcctga cagacctctc atgccggttg aagaacgtga aatcccggaa ctggttgatt
    14161 tgaaagcatt actgagttcc tgtagatggt ctatcagaga gttcagctca gtgtgatccg
    14221 tgaaaacagc ccggatcttt tgcgtcattt cttctatttc acgctctctt tccgcatggg
    14281 cttgattgcg gataagaata ttaaagctgt cactgatgag ctcgtccggt tggaacgtaa
    14341 actgactgac gtactcctcg ttgaagcaca tcacgtcccc aatcccgtca gcaccgatga
    14401 caatgggccc ggtgctatcg gggttttctc cgcgcagccg gaagggcatc agtgcctgta
    14461 gtccctgaat gtcgtcccgc gccgcacagc ttatggcccg tgacagcgta ctttttccag
    14521 taccatttgg cgcaaactta atgttcagtt tatcggcagt gagggtgata tgtgctcgta
    14581 cgatgttatt gcagtggcgt atttcaatgt ccatttatct gtcctttgcc agttattccg
    14641 gggggattca tatcctgccg caaaatgtgc ccgcatgctg tgatgcagat acataataca
    14701 tttcgtttat accattgctt acacctctcc gagatgttca tatcagaaac aaagattagg
    14761 tcgatccgac ttttactttt ttcggatctc tggagagggg aagaaggatt tgtgctgatg
    14821 atgcaatact aatgatatat tttgaactta attgcattat tgcttatctg gcattaataa
    14881 ctgaaatact ttgcataatt atcaatgaaa gaacgaggct catatttccc atgtaaatta
    14941 tatgcccttg cagagagcga gacggtagtg aacttgcggc actaataata aactgtaccg
    15001 actcttcccg ggcactggaa tgttcagatg tacgacagag ccccgcgcct tttgcaataa
    15061 ataattaaag gactgaacat ggcgaccaca gtaatagctg cctttaacga atttatgaaa
    15121 gataccgtga atctcaaaaa ggcagatacc gatgacgcgc gtgcaagtcg cgactggctt
    15181 atcggtaaga tgaatgattt tgagaaggac gataaatttc cggtgagttt tccagcgatc
    15241 catattgcct ttggctcctt tgccagaaga accaaaatcc gtccgcttga tgatatcgat
    15301 ctgatgtttg gcttaaccgg gcaaggtgcc acctatacca tcctgagtga ccggataact
    15361 gtaacctcct ccggagaggg gtcacgtctg cacagttacc gccattccgg agctgacacc
    15421 gtctgctccg tcagaattct gaatgccttt aaaaaccgcc tgcaggacat tgcccagtac
    15481 gcccaggctg atatcaggcg taaccaggaa gctgtcacgc tgaaactggt cagcaaggac
    15541 tggaattttg acatcgtccc ctgctttatt accagcgaag atgcctttgg acggacttac
    15601 tacctgatcc ccgatggcaa cggccactgg aagtttaccg acccccgtaa agacagggac
    15661 agagtcacta ctatcaatgt gcagaataac ggcaatgtgc tcaatgtcat cagagcagtc
    15721 aaatactggc agcggcgacc gacgatgcca tccatgagtt cctacctgct ggaaacgctg
    15781 attctggact attacgctgg caggacatcc tgctcatcgt ttgttgacat ggagctggaa
    15841 gcgcttttcc gccaccttgg tcaatccgtg cggtactctg tcaacgatcc caaaggcata
    15901 cagggtgata tcaactcact ttcagccgag gcacgtaagg cgatatcgga cagatgttat
    15961 ctcgatgcgc aaaaggtatc ggaggcgaga tggtttgaaa ataataaaga gtatgaaaaa
    16021 tccatcaata aatggcgcga tgtgttcggg ccattctttc ctgtttacgg gtgaatcatg
    16081 aatgccattt acacaaacca gtcgaccaga gaaaacatgg atttactgta tgcgcaggcc
    16141 cgtgtctacg acagggtaaa aaactggaac agactgaatt ttctcttcag catcatcgta
    16201 ccgctcctgc tttctttcgt taccgtatac aaccggagcc gggaatttgt cgattcagag
    16261 ttgttgtctt cgctgttggg gttatatgga ctcctggtgc ttacctttaa cattgttatc
    16321 agtggacaca tctcggctct gcgcaggaag gcagcctcaa tccaggaaat gtacgactgc
    16381 cgggtacttg gcatccggcg taatgaactg aaggtggagg agatcccacg ggatgacatc
    16441 atccgggaag ctgcatattt tagagacagc ccggaaaaag cacgaaagcg atttggcgaa
    16501 gaggggtggt acgtcagtaa ggtgtatgac gcgccgcagg ccgtaatggc gctcctttgc
    16561 cacggaaaaa atctcggctg ggacaaatcg ctcagggagg ttctgcacgt attttatctt
    16621 tccgctttta ttgtctcgcc tgtcgcgatg cttgtttacg gcatcgtcat gaaatccggg
    16681 ctgaatgaga tcctcttcta tgtggtgttc acactgccgg tcatccgcta tttcttgctt
    16741 cagtttctgg ataatcgcag cagtatgaaa agaagcgaga agctgaaaaa gcacgttgag
    16801 aaggaattat ccggcataag ggtgtccgga agggcagaag aagagcaact ggcttatacg
    16861 ctccggaata tccaagatga gatgtttacc taccgggcct catgtccgcc cgtacccaac
    16921 ggtattcagc tgataatgaa gcccaaaaat gaacgaattt atgttgatta ctttgaaaca
    16981 aatctgaagg agctgcacct tcagaagtaa tccctcctta gctccggtgt aggatttacg
    17041 tatgccggag cacatccgat aaacaattct tggttgcctg agtgtcagcg taaacccata
    17101 gtcaccttcg cctcagacgg ttagtaacac aggtaatgac tccaactta
//
LOCUS       DACAOP010000095        16850 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.095, whole genome shotgun sequence.
ACCESSION   DACAOP010000095 DACAOP010000000
VERSION     DACAOP010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16850
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.095"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..758)
                     /gene="dmpG"
                     /locus_tag="IT892_003512"
     CDS             complement(<1..758)
                     /gene="dmpG"
                     /locus_tag="IT892_003512"
                     /EC_number="4.1.3.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="HAP3136690.1"
                     /translation="MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSI
                     EVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQA
                     GARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGA
                     TCIYVVDSGGAMNMSDIRDRFRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCD
                     RIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGT"
     gene            complement(755..1705)
                     /locus_tag="IT892_003513"
     CDS             complement(755..1705)
                     /locus_tag="IT892_003513"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HAP3136691.1"
                     /translation="MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGL
                     ARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDL
                     TPAAIGPYCVPVVNLEANVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIAS
                     KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEAS
                     QDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEV
                     EGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA"
     gene            complement(1702..2511)
                     /gene="mhpD"
                     /locus_tag="IT892_003514"
     CDS             complement(1702..2511)
                     /gene="mhpD"
                     /locus_tag="IT892_003514"
                     /EC_number="4.2.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="HAP3136692.1"
                     /translation="MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHI
                     NVQHDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNEIIPFSRVLQP
                     RIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNAS
                     CGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASL
                     GEPLRTGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFSSAAPKGSLS"
     gene            complement(2521..3387)
                     /locus_tag="IT892_003515"
     CDS             complement(2521..3387)
                     /locus_tag="IT892_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414883.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-6-oxononadienedioate/2-hydroxy-6-
                     oxononatrienedioate hydrolase"
                     /protein_id="HAP3136693.1"
                     /translation="MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGS
                     GPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSVVNSGSRSDLNARILKSVVDQ
                     LDIAKIHLLGNSMGGHSSVAFTLKWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQ
                     LYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFP
                     DFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADA
                     FNQLVLNFLARP"
     gene            complement(3405..4349)
                     /locus_tag="IT892_003516"
     CDS             complement(3405..4349)
                     /locus_tag="IT892_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydroxyphenylpropionate/2,
                     3-dihydroxicinnamic acid 1,2-dioxygenase"
                     /protein_id="HAP3136694.1"
                     /translation="MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPE
                     LVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSG
                     IDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGR
                     FTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVIS
                     AAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWV
                     AAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN"
     gene            complement(4351..6015)
                     /locus_tag="IT892_003517"
     CDS             complement(4351..6015)
                     /locus_tag="IT892_003517"
                     /EC_number="1.14.13.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="HAP3136695.1"
                     /translation="MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVV
                     EKLDKLIDYPRAIGIDDEALRTMQSVGLVDDVLPHTTPWHAMRFLTPKGRCFADIQPM
                     TDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCLFSRELEAFSQQDDEVTLHLKTAEG
                     QREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDP
                     VRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYT
                     HNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDAL
                     LDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMR
                     FKPMPQYYGGALMREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
                     PLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNA
                     SLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA"
     gene            6092..7039
                     /gene="mhpR"
                     /locus_tag="IT892_003518"
     CDS             6092..7039
                     /gene="mhpR"
                     /locus_tag="IT892_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator MhpR"
                     /protein_id="HAP3136696.1"
                     /translation="MIFYCALSIGRVFSATIKTCPNVHQVHHVVLTIEMSINMQNNEQ
                     TEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLHRTTVRRLLETLQEEGYVRRS
                     PSDDSFRLTIKVRQLSEGFRDEQWISALAAPLLGDLLREVVWPTDVSTLDVDAMVVRE
                     TTHRFSRLSFHRAMVGRRLPLLKTASGLTWLAFCPEQDRKELIEMLASRPGDDYQLAR
                     EPLKLEAILARARKEGYGQNYRGWDQEEKIASIAVPLRSEQRVIGCLNLVYMASAMTI
                     EQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGMHLR"
     gene            7116..8198
                     /locus_tag="IT892_003519"
     CDS             7116..8198
                     /locus_tag="IT892_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414879.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP3136697.1"
                     /translation="MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAE
                     LNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERS
                     GVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQTPINSII
                     FSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAEREG
                     DWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDT
                     EDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNT
                     QTASPRALADSLMQLARQVSRLESGQ"
     gene            8321..11395
                     /locus_tag="IT892_003520"
     CDS             8321..11395
                     /locus_tag="IT892_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HAP3136698.1"
                     /translation="MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
                     TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYT
                     NVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
                     GYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
                     PTTQISDFHVATRFNDDFSRAVLEAEVQMCGELRDYLRVTVSLWQGETQVASGTAPFG
                     GEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFR
                     EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
                     YPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
                     HPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVD
                     EDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
                     FVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQ
                     QQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIE
                     LPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPH
                     LTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSE
                     ATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKT
                     YRIDGSGQMAITVDVEVASDTPHPARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAA
                     CFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETS
                     HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
     gene            11447..12700
                     /gene="lacY"
                     /locus_tag="IT892_003521"
     CDS             11447..12700
                     /gene="lacY"
                     /locus_tag="IT892_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactose permease"
                     /protein_id="HAP3136699.1"
                     /translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
                     TGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
                     ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGI
                     MFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFR
                     QPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIM
                     FFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCF
                     KYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGF
                     TLISVFTLSGPGPLSLLRRQVNEVA"
     gene            12766..13377
                     /gene="lacA"
                     /locus_tag="IT892_003522"
     CDS             12766..13377
                     /gene="lacA"
                     /locus_tag="IT892_003522"
                     /EC_number="2.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactoside O-acetyltransferase"
                     /protein_id="HAP3136700.1"
                     /translation="MNMPMTERIRAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEV
                     EKRESLIKEMFATVGENAWVEPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNV
                     LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGA
                     GSIVTKDIPPNVVAAGVPCRVIREINDRDKHYYFKDYKVESSV"
     gene            complement(13480..14661)
                     /gene="cynX"
                     /locus_tag="IT892_003523"
     CDS             complement(13480..14661)
                     /gene="cynX"
                     /locus_tag="IT892_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308421.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanate transporter CynX"
                     /protein_id="HAP3136701.1"
                     /translation="MRNHQKTFTMLLVLVLIGLNMRPLLTSVGPLLPQLRQASGMSFS
                     VAALLTALPVVTMGGLALAGSWLHQHVSERRSVAISLLLIAVGALMRELYPQSALLLS
                     SALLGGVGIGIIQAVMPSVIKRRFQQRTPLVMGLWSAALMGGGGLGAAITPWLVQHSE
                     TWYQTLAWWALPAVVALFAWWWQSAREVASSHKTTTTPVRVVFTPRAWTLGVYFGLIN
                     GGYASLIAWLPAFYIEIGASAQYSGSLLALMTLGQAAGALLMPAMARHQDRRKLLMLA
                     LVLQLVGFCGFIWLPMQLPVLWAMVCGLGLGGAFPLCLLLALDHSVQPAIAGKLVAFM
                     QGIGFIIAGLAPWFSGVLRSISGNYLMDWAFHALCVVGLMIITLRFAPVRFPQLWVKE
                     A"
     gene            complement(14667..15137)
                     /gene="cynS"
                     /locus_tag="IT892_003524"
     CDS             complement(14667..15137)
                     /gene="cynS"
                     /locus_tag="IT892_003524"
                     /EC_number="4.2.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanase"
                     /protein_id="HAP3136702.1"
                     /translation="MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVT
                     AALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQ
                     VYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF"
     gene            complement(15168..15827)
                     /locus_tag="IT892_003525"
     CDS             complement(15168..15827)
                     /locus_tag="IT892_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HAP3136703.1"
                     /translation="MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRL
                     VPELVTQREPGDLFVIRNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCG
                     AMTAIASCQCMDHMPAVSHWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANL
                     QTHPSVRLALEEGRIALHGWVYDIESGSIAAFDGATRQFVPLAANPRVCAIPLRQPTA
                     A"
     gene            15936..16835
                     /gene="cynR"
                     /locus_tag="IT892_003526"
     CDS             15936..16835
                     /gene="cynR"
                     /locus_tag="IT892_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414872.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CynR"
                     /protein_id="HAP3136704.1"
                     /translation="MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLG
                     VPLFDRSGRTIRLTDAGEVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFT
                     SYFIGPLMADFYARYPSITLQLQEMSQEKIEDMLCRDELDVGIAFAPVHSPELEAIPL
                     LTESLALVVAQHHPLAVHEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVV
                     IEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAISLAPPLLERTAVLLRRKNSWQT
                     AAAKAFLHMALDKCAVVGGNESR"
BASE COUNT         3880 a         4674 c         4494 g         3802 t
ORIGIN      
        1 tcggtcccat gctgccagcc cagtttatcc gcggcggcaa taaacacttc cagcggtgcg
       61 ttacctgcgc ccgcgcccat tcccgcgagg ctggcgtcga ttcggtcgca gccctcttcc
      121 accgccgcga tagagttcgc cacgccaaga ctcaggttat ggtgagcgtg catgccagtt
      181 tgcgtttctg gtttcagctc tgctttcagg gcgcggaaac ggtcacggat atcgctcatg
      241 ttcatcgcac cgccagaatc caccacataa atacaggtcg caccgtagcc ttccatcagc
      301 tttgcctgct tggcgagatt ctccggcgtg gtcatatggc tcatcatcag aaaaccaacg
      361 gtgtccattc cgagctcgcg ggcatactga atatgctggg cggaaacatc agcttcggta
      421 cagtgcgttg ccacacgaac cacccgcgcg ccagcctgcc aggcattttt cagatcgtga
      481 atagtgccga ttcctggcag caacaacgtc gcgattttgg cgtgcttcac cacatccgcc
      541 gccgcttcaa tccattcaag gtcgctatgt gcgccgaaac catagttaaa gctggaacct
      601 tgcaaaccgt cgccgtgggc cacttcaatc gaatccacgc gggcatcgtc cagtgctttg
      661 gcaatctggc gaacgttttc cagcgaatac tgatgacgaa tggcgtgcat accgtcacgc
      721 aatgtgacgt ccgagatata aagtttttta ccgttcatgc cgcttctcct gccttgcgcg
      781 ccagtgactg ggccattttt tccgctgtcg ccagcgcact ggaagtcata atgtcgaggt
      841 tgcccgcata ggcaggcaga taatgcgctg cgccttcgac ttccagccag accgctgttt
      901 tcagtccgga gaattgcccc acgcccggta aattgaccgg tttatcctgc gggataactt
      961 caaactgcac gcgctgtttc aggcgataac ccggtacgta agcctgcacc gcctcagcca
     1021 tttcattgat tgaggcttcg atatcatctt gtgaagcttc gtcgctcaat acatacaccg
     1081 tgtcacgcat catcaacggt ggctctgctg ggttaagcac aataatcgcc ttcccttttg
     1141 ccgcgccgcc caccacttca atggctcggg aagtggtttc cgtaaattca tcgatattgg
     1201 cacgcgtgcc aggtccggca gatttactgg cgatagaagc gataatttcg gcgtaatgaa
     1261 cacgcgccac gcgtgaaact gccgccacca ttggaatggt ggcctggccg ccgcaggtga
     1321 ccatgttgac gttcagttga tcgacgttcg cctcgaggtt aaccaccggc acgcagtaag
     1381 ggccgatggc agcaggcgtc aggtcaatta agcgaatatc cggtttcgct tcgcgtaaag
     1441 cggcatcgtt tttcacatga gcaccggcgc tggtcgcatc aaatacaatg tcgatatcag
     1501 caaattcagg catgttcatc agtccgatca ccccttcatg ggtggtggcg acgcccatac
     1561 gtctggcgcg cgccagaccg tcggactgag gatcaatgcc aaccatcacc gccatctcca
     1621 gatgctgacc gtgacgcaaa attttaatca tcagatcggt accaatattg ccagaaccga
     1681 taatggcgac tttacgctta ctcatgacag acttcctttt ggggctgcgc ttgaaaatgt
     1741 cgcagcaact gaacctatgc cttcaatatg ggcttcaaaa cgatcgcccg cattcaccgc
     1801 caccatcgga cctaatgccc cggtaagaat gatatctccg gtgcgcagcg gttcacccag
     1861 actggccatt ttgcgtgcca gccagacggc cgcattaagc ggatgtccca ggcattcgct
     1921 gccgcgcccg ctagaaacct cttcgttatt acgcgtcatc ttcatggcgc agtttttcag
     1981 gtctaacccc gccggacgtt gcgccggacc gccgatgaca tacaccccac aggaggcgtt
     2041 atctgccacg gtatcgacaa actgaatcga ccagtcgcga atgcggctcc ccaccacttc
     2101 cagcgccgga agtacccatt caatggcgtt atacaattcg tcgaaggtga tatcggttgc
     2161 gggcaaatcg cggttcaaca ccagtgcgat ctccgcttca atgcggggtt gcagaacacg
     2221 ggaaaaagga atgatttcgt tatcgccata acacatgtcg gcaaataacg tcccaaaatc
     2281 cggttgatca acgcccagtt gttgttgcac tttcggatgt gtcaggccca ctttacgccc
     2341 taccacgcga cgcccctgcg caacgtcatg ttgcacattt atgtgctgaa tggcgtaagc
     2401 cgcttcagcg ttatcgatac caatcagatc gcgcagcggt gcaatcgctt cgccctgctc
     2461 tgcggcgcgg cgtaaatccg ccgccagttg ctcaagagta tgcttcgtca tgaccattcc
     2521 ttaagggcgt gcgaggaaat tcagcaccag ttgattgaaa gcgtcggcat gttcccactg
     2581 cgcccagtga ccacagtcgc ggaagatatg cagttcagaa ccggcaatgc cggacagcag
     2641 acgcagaccc gcatccatcg gcacaaagcg gtcgttgcgc ccccagacaa tcagggtttg
     2701 cgctttgatt tccgccagac gtgggccaaa atccgggaac tgtttcggat tagcttccag
     2761 gctcttaacg aagttttcca ggtgatcgcg gcgcgacagc atattattca ggcgcgcttc
     2821 aaacagggcg tcggtcaaat cgctggtatc aaaaacgaag atatccatca tcagcttcag
     2881 gttttcgata gtcggctgac gataaagctg attcagtcgc ttaatacctt cggttggcat
     2941 cggcgtaaac aaactcatgc cgcccgtacc gccgcccatc agcaccagtt tgccgacgcg
     3001 ctccggccat ttaagggtga acgccacaga actatggccc cccatcgagt tgcccagcag
     3061 gtggattttg gcgatatcca gttgatccac cacgcttttc aggattcgtg cattaagatc
     3121 cgatcgcgaa ccactattaa cgaccgaatc gctcttgccc caacccggac aatccagcag
     3181 gatcacccga tagcccgcct ctaccagcgg atcgatattg cggctgaagt tcgcccagcc
     3241 agtagcaccc gggccggaac catgcagcag gacaacggtt tcgtcgcctt gtccgcagtc
     3301 attaaaatgg atgcgcagcg ttttacccgc ttcttctaca ttcagaaaac ggctggtggc
     3361 ggcttcggtt tgtggctgat aactcatcat cttctcctgc atattcagtt ctctgttctg
     3421 gcgcttaacg agccaaatcc ggcaatccac tccgggattg ggcggtaata acgcccttcg
     3481 ctacgccagt tgccaaacgc agaaatagcg gcaaaagcgg cgacccaggt tttgatttca
     3541 tgtgtcgact ttccggcaat ggcggaaagc tcttcgttac tgacggcatc cagttcctgt
     3601 atgcgtccct gctccagcaa agtcatgaac tggttatccc aaatcgggtt gagcggatgc
     3661 agcgttctct gatcctcaac aaacttctca gcggcgctaa tcacccgttg ctgacgcaat
     3721 tcgcgctcac tggcgggtaa atctttcccg ctccccaaca gacggtcgcg catatgggca
     3781 tcggctttcg ccagttcggg caccggcggc tgatgggaaa gcccaccgga acccaggaac
     3841 agcacgcgtt tattgagagt gctggtgaaa cgtccaatgg cttcacccaa catgcgggta
     3901 cgctggaaac cgggcagcgg cgtggcgaca ccgttgatga acacaggcag aactggcacc
     3961 ttatccagcc caccgagcag gaactccagc ggctgggcga acccgtggtc cacctgcata
     4021 cagtaagaaa cggcaagatc gatcccgctc ttcatgacgg catgcgcaca ggcctccgcc
     4081 agctccacag gcacgggcag ctctcctgcc gcactgccga aatcaccaat tgccgtcgct
     4141 ccaacgccta aacagaacgg tggcatcacg tcatagaaaa agccgttgta gtgatctggc
     4201 gcaaacagca ccaccagttc aggggagaat gccgcaatac gctcgcgggc gctggcaatc
     4261 acgccattga cctcatcgag cacctcttgc gccgggtcga cataccccac cagcggcgag
     4321 tgggaaagac agtgaagata agcgtgcata tcaggctacc ttttcgacag aaacgtcggc
     4381 atcagggcgg gtcagcgtca tcaccgacgc cagtttattc agggtcttgc ccagggtttg
     4441 cggaatggcg gtggcggcaa caaagcgatc cgggcgcatc accaccagcg aagcattgtg
     4501 ttgcgcgaac cagctacgca ggcgaccttg cgtatcgccc acgcgtagta cgccgtcgtg
     4561 gttatcctgt gcggtatgaa tttgcacttc cggcaccacc tgaatgaagc gtgtgcccaa
     4621 cgcgcgccac tgctggattt gctcgtcgct catcccccac agtggattgc atccccagcc
     4681 aattaccgcg aagttcgcgc cgatcgcgtt atcgagcagc gtcacgtcgc cgttttccag
     4741 cgtgactttc ggctgaataa acatcttgcc gaccggagag tgcttcgctt cgccctcacg
     4801 catcagcgca ccgccgtaat attgcggcat cggcttgaag cgcatttcga ggaagtagcg
     4861 ttttactggc ggcagataat tcaacagcca ggaaacgccg tcacgtaacg taccctgcca
     4921 gcgtttcggc ggagccagca cgttgcccgc cgtcacggac aggtcaatca tcgctttggc
     4981 gtgatcgcga cgttcttgtt gataggtatc gagcagcgca tcgcgggctt tcccctggat
     5041 aaccaacgcc agtttccatg cgaggttaaa ggcgtcgcgc ataccactgt tatagccctg
     5101 cccctgccat accggcatga tgtgcgcggc atcgcccgcc agcagtacgc gatcaatacg
     5161 gaaacgttgc gccagtcgcg cgttgtgggt gtagacacgc tggcgaatca attcaacatt
     5221 gtccggatta ggcagcactt tgcttaacag cttgcgcata ttttgcggct cacgcagctg
     5281 ctcttcggtt tctcccggca tcaccataaa ttcaaagcga cgtaccgcat gaggcagcgc
     5341 ggcagaaaca tacgggcgca ccggatcgca acacaaatag atatgcggcg tacttaacgg
     5401 atcgttggcg atatctacca caatccactg atttggcgca gttttacctt caaacggcac
     5461 attcagagtg cgacggacaa aacttgctcc accgtcacag gctaccagcc actgggcttt
     5521 gactatttcc cgctgccctt ctgccgtttt caggtgcaag gtcacttcgt catcttgctg
     5581 actgaaggcc tccagctcgc gggaaaacaa gcagcgcaca ttcggaaaac gcgacacccc
     5641 ttccagcatc accgcatcga cctgcggctg aataaaggcg ttacggcgcg gccagccaaa
     5701 ttcatcggtc attggctgaa tatcagcaaa acagcggcct ttcggggtga gaaaacgcat
     5761 cgcgtgccac ggcgtagtgt gcggcagaac atcatcgacc aggccgaccg actgcatggt
     5821 gcgcagcgcc tcgtcatcaa taccaatcgc acgcgggtag tcgatcaact tatcgagttt
     5881 ctccaccacc agcacgtcaa tgcccatctg gccgagatag ttcgccatca tcagcccaac
     5941 cgggccggca ccagcgatcg ccacctgaac gctatggtta acagcaggct ggatgtcagg
     6001 gtgttgtatt gccatttcag tacctcacga ctcggacaaa atgtcgttgc gcgcacagta
     6061 cagcgcaact tattttgtta aaaacatgta aatgattttt tattgtgcgc tcagtatagg
     6121 aagggtgttt tcggctacaa tcaaaacatg cccgaatgtg caccaggtgc accacgttgt
     6181 tttaactata gaaatgtcaa ttaatatgca gaacaatgag cagacggaat acaaaaccgt
     6241 gcgcggctta acccgcggtc taatgttatt aaatatgtta aataaacttg atggcggtgc
     6301 cagcgtcggg ctgctggcgg aactcagcgg cctgcatcgc accactgtgc ggcgactgct
     6361 ggagacgctg caggaagagg gatatgtccg ccgtagcccc tccgatgata gttttcgact
     6421 gaccatcaaa gtgcggcaat taagcgaagg atttcgtgac gaacagtgga tttctgcact
     6481 ggcggcccca ctgctgggcg atctgttgcg cgaagtggta tggccgacag atgtgtccac
     6541 gctggatgtt gatgcaatgg tggtacgcga aaccactcac cgtttcagcc gcttatcctt
     6601 tcaccgggca atggtcgggc gacgtttgcc gcttctgaaa accgcctcgg gcctgacctg
     6661 gctggccttt tgcccggaac aagaccgcaa ggaattaatc gaaatgttag cctcccgccc
     6721 cggtgatgac tatcaactgg cacgggaacc gttaaagctg gaagccattc tggcgcgcgc
     6781 gcgcaaagag ggttacggac agaactatcg cggctgggat caggaggaga agatcgcctc
     6841 tatcgccgta ccgctgcgca gtgaacaacg ggtgattggc tgtctgaatc tggtgtatat
     6901 ggcgagcgca atgaccattg aacaggcagc ggaaaagcat cttccggcgc tacaacgggt
     6961 agcaaaacag atcgaagaag gggttgaatc gcaggctatt ctggtggccg gaaggcgaag
     7021 cggcatgcat ttacgttgac accatcgaat ggcgcaaaac ctttcgcggt atggcatgat
     7081 agcgcccgga agagagtcaa ttcagggtgg tgaatgtgaa accagtaacg ttatacgatg
     7141 tcgcagagta tgccggtgtc tcttatcaga ccgtttcccg cgtggtgaac caggccagcc
     7201 acgtttctgc gaaaacgcgg gaaaaagtgg aagcggcgat ggcggagctg aattacattc
     7261 ccaaccgcgt ggcacaacaa ctggcgggca aacagtcgtt gctgattggc gttgccacct
     7321 ccagtctggc cctgcacgcg ccgtcgcaaa ttgtcgcggc gattaaatct cgcgccgatc
     7381 aactgggtgc cagcgtggtg gtgtcgatgg tagaacgaag cggcgtcgaa gcctgtaaag
     7441 cggcggtgca caatcttctc gcgcaacgcg tcagtgggct gatcattaac tatccgctgg
     7501 atgaccagga tgccattgct gtggaagctg cctgcactaa tgttccggcg ttatttcttg
     7561 atgtctctga ccagacaccc atcaacagta ttattttctc ccatgaagac ggtacgcgac
     7621 tgggcgtgga gcatctggtc gcattgggtc accagcaaat cgcgctgtta gcgggcccat
     7681 taagttctgt ctcggcgcgt ctgcgtctgg ctggctggca taaatatctc actcgcaatc
     7741 aaattcagcc gatagcggaa cgggaaggcg actggagtgc catgtccggt tttcaacaaa
     7801 ccatgcaaat gctgaatgag ggcatcgttc ccactgcgat gctggttgcc aacgatcaga
     7861 tggcgctggg cgcaatgcgc gccattaccg agtccgggct gcgcgttggt gcggatatct
     7921 cggtagtggg atacgacgat accgaagaca gctcatgtta tatcccgccg ttaaccacca
     7981 tcaaacagga ttttcgcctg ctggggcaaa ccagcgtgga ccgcttgctg caactctctc
     8041 agggccaggc ggtgaagggc aatcagctgt tgcccgtctc actggtgaaa agaaaaacca
     8101 ccctggcgcc caatacgcaa accgcctctc cccgcgcgtt ggccgattca ttaatgcagc
     8161 tggcacgaca ggtttcccga ctggaaagcg ggcagtgagc gcaacgcaat taatgtgagt
     8221 tagctcactc attaggcacc ccaggcttta cactttatgc ttccggctcg tatgttgtgt
     8281 gaaattgtga gcggataaca atttcacaca ggaaacagct atgaccatga ttacggattc
     8341 actggccgtc gttttacaac gtcgtgactg ggaaaaccct ggcgttaccc aacttaatcg
     8401 ccttgcagca catccccctt tcgccagctg gcgtaatagc gaagaggccc gcaccgatcg
     8461 cccttcccaa cagttgcgca gcctgaatgg cgaatggcgc tttgcctggt ttccggcacc
     8521 agaagcggtg ccggaaagct ggctggagtg cgatcttcct gaggccgata ctgtcgtcgt
     8581 cccctcaaac tggcagatgc acggttacga tgcgcccatc tacaccaacg tgacctatcc
     8641 cattacggtc aatccgccgt ttgttcccac ggagaatccg acgggttgtt actcgctcac
     8701 atttaatgtt gatgaaagct ggctacagga aggccagacg cgaattattt ttgatggcgt
     8761 taactcggcg tttcatctgt ggtgcaacgg gcgctgggtc ggttacggcc aggacagtcg
     8821 tttgccgtct gaatttgacc tgagcgcatt tttacgcgcc ggagaaaacc gcctcgcggt
     8881 gatggtgctg cgctggagtg acggcagtta tctggaagat caggatatgt ggcggatgag
     8941 cggcattttc cgtgacgtct cgttgctgca taaaccgact acacaaatca gcgatttcca
     9001 tgttgccact cgctttaatg atgatttcag ccgcgctgta ctggaggctg aagttcagat
     9061 gtgcggcgag ttgcgtgact acctacgggt aacagtttct ttatggcagg gtgaaacgca
     9121 ggtcgccagc ggcaccgcgc ctttcggcgg tgaaattatc gatgagcgtg gtggttatgc
     9181 cgatcgcgtc acactacgtc tgaacgtcga aaacccgaaa ctgtggagcg ccgaaatccc
     9241 gaatctctat cgtgcggtgg ttgaactgca caccgccgac ggcacgctga ttgaagcaga
     9301 agcctgcgat gtcggtttcc gcgaggtgcg gattgaaaat ggtctgctgc tgctgaacgg
     9361 caagccgttg ctgattcgag gcgttaaccg tcacgagcat catcctctgc atggtcaggt
     9421 catggatgag cagacgatgg tgcaggatat cctgctgatg aagcagaaca actttaacgc
     9481 cgtgcgctgt tcgcattatc cgaaccatcc gctgtggtac acgctgtgcg accgctacgg
     9541 cctgtatgtg gtggatgaag ccaatattga aacccacggc atggtgccaa tgaatcgtct
     9601 gaccgatgat ccgcgctggc taccggcgat gagcgaacgc gtaacgcgaa tggtgcagcg
     9661 cgatcgtaat cacccgagtg tgatcatctg gtcgctgggg aatgaatcag gccacggcgc
     9721 taatcacgac gcgctgtatc gctggatcaa atctgtcgat ccttcccgcc cggtgcagta
     9781 tgaaggcggc ggagccgaca ccacggccac cgatattatt tgcccgatgt acgcgcgcgt
     9841 ggatgaagac cagcccttcc cggctgtgcc gaaatggtcc atcaaaaaat ggctttcgct
     9901 acctggagag acgcgcccgc tgatcctttg cgaatacgcc cacgcgatgg gtaacagtct
     9961 tggcggtttc gctaaatact ggcaggcgtt tcgtcagtat ccccgtttac agggcggctt
    10021 cgtctgggac tgggtggatc agtcgctgat taaatatgat gaaaacggca acccgtggtc
    10081 ggcttacggc ggtgattttg gcgatacgcc gaacgatcgc cagttctgta tgaacggtct
    10141 ggtctttgcc gaccgcacgc cgcatccagc gctgacggaa gcaaaacacc agcagcagtt
    10201 tttccagttc cgtttatccg ggcaaaccat cgaagtgacc agcgaatacc tgttccgtca
    10261 tagcgataac gagctcctgc actggatggt ggcgctggat ggtaagccgc tggcaagcgg
    10321 tgaagtgcct ctggatgtcg ctccacaagg taaacagttg attgaactgc ctgaactacc
    10381 gcagccggag agcgccgggc aactctggct cacagtacgc gtagtgcaac cgaacgcgac
    10441 cgcatggtca gaagccgggc acatcagcgc ctggcagcag tggcgtctgg cggaaaacct
    10501 cagtgtgacg ctccccgccg cgtcccacgc catcccgcat ctgaccacca gcgaaatgga
    10561 tttttgcatc gagctgggta ataagcgttg gcaatttaac cgccagtcag gctttctttc
    10621 acagatgtgg attggcgata aaaaacaact gctgacgccg ctgcgcgatc agttcacccg
    10681 tgcaccgctg gataacgaca ttggcgtaag tgaagcgacc cgcattgacc ctaacgcctg
    10741 ggtcgaacgc tggaaggcgg cgggccatta ccaggccgaa gcagcgttgt tgcagtgcac
    10801 ggcagataca cttgctgatg cggtgctgat tacgaccgct cacgcgtggc agcatcaggg
    10861 gaaaacctta tttatcagcc ggaaaaccta ccggattgat ggtagtggtc aaatggcgat
    10921 taccgttgat gttgaagtgg cgagcgatac accgcatccg gcgcggattg gcctgaactg
    10981 ccagctggcg caggtagcag agcgggtaaa ctggctcgga ttagggccgc aagaaaacta
    11041 tcccgaccgc cttactgccg cctgttttga ccgctgggat ctgccattgt cagacatgta
    11101 taccccgtac gtcttcccga gcgaaaacgg tctgcgctgc gggacgcgcg aattgaatta
    11161 tggcccacac cagtggcgcg gcgacttcca gttcaacatc agccgctaca gtcaacagca
    11221 actgatggaa accagccatc gccatctgct gcacgcggaa gaaggcacat ggctgaatat
    11281 cgacggtttc catatgggga ttggtggcga cgactcctgg agcccgtcag tatcggcgga
    11341 attccagctg agcgccggtc gctaccatta ccagttggtc tggtgtcaaa aataataata
    11401 accgggcagg ccatgtctgc ccgtatttcg cgtaaggaaa tccattatgt actatttaaa
    11461 aaacacaaac ttttggatgt tcggtttatt ctttttcttt tactttttta tcatgggagc
    11521 ctacttcccg tttttcccga tttggctaca tgacatcaac catatcagca aaagtgatac
    11581 gggtattatt tttgccgcta tttctctgtt ctcgctatta ttccaaccgc tgtttggtct
    11641 gctttctgac aaactcgggc tgcgcaaata cctgctgtgg attattaccg gcatgttagt
    11701 gatgtttgcg ccgttcttta tttttatctt cgggccactg ttacaataca acattttagt
    11761 aggatcgatt gttggtggta tttatctagg cttttgtttt aacgccggtg cgccagcagt
    11821 agaggcattt attgagaaag tcagccgtcg cagtaatttc gaatttggtc gcgcgcggat
    11881 gtttggctgt gttggctggg cgctgtgtgc ctcgattgtc ggcatcatgt tcaccatcaa
    11941 taatcagttt gttttctggc tgggctctgg ctgtgcactc atcctcgccg ttttactctt
    12001 tttcgccaaa acggatgcgc cctcttctgc cacggttgcc aatgcggtag gtgccaacca
    12061 ttcggcattt agccttaagc tggcactgga actgttcaga cagccaaaac tgtggttttt
    12121 gtcactgtat gttattggcg tttcctgcac ctacgatgtt tttgaccaac agtttgctaa
    12181 tttctttact tcgttctttg ctaccggtga acagggtacg cgggtatttg gctacgtaac
    12241 gacaatgggc gaattactta acgcctcgat tatgttcttt gcgccactga tcattaatcg
    12301 catcggtggg aaaaacgccc tgctgctggc tggcactatt atgtctgtac gtattattgg
    12361 ctcatcgttc gccacctcag cgctggaagt ggttattctg aaaacgctgc atatgtttga
    12421 agtaccgttc ctgctggtgg gctgctttaa atatattacc agccagtttg aagtgcgttt
    12481 ttcagcgacg atttatctgg tctgtttctg cttctttaag caactggcga tgatttttat
    12541 gtctgtactg gcgggcaata tgtatgaaag catcggtttc cagggcgctt atctggtgct
    12601 gggtctggtg gcgctgggct tcaccttaat ttccgtgttc acgcttagcg gccccggccc
    12661 gctttccctg ctgcgtcgtc aggtgaatga agtcgcttaa gcaatcaatg tcggatgcgg
    12721 cgcgagcgcc ttatccgacc aacatatcat aacggagtga tcgcattgaa catgccaatg
    12781 accgaaagaa taagagcagg caagctattt accgatatgt gcgaaggctt accggaaaaa
    12841 agacttcgtg ggaaaacgtt aatgtatgag tttaatcact cgcatccatc agaagttgaa
    12901 aaaagagaaa gcctgattaa agaaatgttt gccacggtag gggaaaacgc ctgggtagaa
    12961 ccgcctgtct atttctctta cggttccaac atccatatag gccgcaattt ttatgcaaat
    13021 ttcaatttaa ccattgtcga tgactacacg gtaacaatcg gtgataacgt actgattgca
    13081 cccaacgtta ctctttccgt tacgggacac cctgtacacc atgaattgag aaaaaacggc
    13141 gagatgtact cttttccgat aacgattggc aataacgtct ggatcggaag tcatgtggtt
    13201 attaatccag gcgtcaccat cggggataat tctgttattg gcgcgggtag tatcgtcaca
    13261 aaagacattc caccaaacgt cgtggcggct ggcgttcctt gtcgggttat tcgcgaaata
    13321 aacgaccggg ataagcacta ttatttcaaa gattataaag ttgaatcgtc agtttaaatt
    13381 ataaaaattg cctgatacgc tgcgcttatc aggcctacaa gttcagcgat ctacattagc
    13441 cgcatccggc atgaacaaag cgcaggaaca agcgtcgcat catgcctctt tgacccacag
    13501 ctgcggaaaa cgtactggtg caaaacgcag ggttatgatc atcagcccaa cgacgcacag
    13561 cgcatgaaat gcccagtcca tcaggtaatt gccgctgata ctacgcagca cgccagaaaa
    13621 ccacggggca agcccggcga tgataaaacc gattccctgc ataaacgcca ccagcttgcc
    13681 agcaatagcc ggttgcacag agtgatcgag cgccagcagc aaacagagcg gaaacgcgcc
    13741 gcccagacct aacccacaca ccatcgccca caataccggc aattgcatcg gcagccagat
    13801 aaagccgcag aaccccacca gttgtaacac cagcgccagc attaacagtt tgcgccgatc
    13861 ctgatggcga gccatagcag gcatcagcaa agctcctgcg gcttgcccaa gcgtcatcaa
    13921 tgccagtaag gaaccgctgt actgcgcgct ggcaccaatc tcaatataga aagcgggtaa
    13981 ccaggcaatc aggctggcgt aaccgccgtt aatcagaccg aagtaaacac ccagcgtcca
    14041 cgcgcgggga gtgaatacca cgcgaaccgg agtggttgtt gtcttgtggg aagaggcgac
    14101 ctcgcgggcg ctttgccacc accaggcaaa gagcgcaaca acggcaggca gcgcccacca
    14161 ggcgagtgtt tgataccagg tttcgctatg ttgaactaac cagggcgtta tggcggcacc
    14221 aagcccaccg ccgcccatca gagccgcgga ccacagcccc atcaccagtg gcgtgcgctg
    14281 ctgaaaccgc cgtttaatca ccgaaggcat caccgcctga atgatgccga tccccacccc
    14341 accaagcagt gcgctgctaa gcagcagcgc actttgcggg taaagctcac gcatcaatgc
    14401 accgacggca atcagcaaca gactgatggc gacactgcga cgttcgctga catgctgatg
    14461 aagccagctt ccggccagcg ccagcccgcc catggtaacc accggcagag cggtcaacag
    14521 ggcagccacg ctaaagctca ttccgctcgc ctggcgcaat tgcggtagca gtggcccgac
    14581 ggaggtgagc agtggtcgca tattaagacc aatcagcacc agtaccagca gcatcgtgaa
    14641 cgtcttttga tggttgcgca tggctgtcag aacggtttgg tcggcagata tttaccatct
    14701 aaggtgatga ccgcacgttc gccaccttcc gggtccgcca ctttcttaac gtcgagtttg
    14761 aagttaatcg cgctaataat gccatcgcca aatttctcat gaaccaacgc tttcagggtt
    14821 gtaccgtaca cctgcaacat ttcatagaaa cgatacatcg ttgggtcagt tggaatacgg
    14881 tcatcaatgc agccacgcag tggaatcatc tgcaacagta gaatggagtc ttcgtcgaga
    14941 tccagcttcg ccccgaccag gcgggcggcg tcggcaggaa gcgcctgctg acccagcaaa
    15001 gccgcggtta caaaggcttc tgccagaccg gtgccgtcgg caatctcggc aaatgagaga
    15061 tcttttttag ctttgctgag caaaatggca tcggcaagat caagacgaat attgcggtta
    15121 atttgtgact gaatcatggt ggaactcctg atggtttaaa aataaggtta cgctgcggtc
    15181 ggttggcgta gcggtatggc acaaacgcga ggattagcgg ccagtggcac aaactggcgg
    15241 gttgcgccgt caaaagctgc gatgctgccg ctttcaatgt cgtagaccca gccgtgcagg
    15301 gcgatccgcc cctcttcgag cgccaggcgc accgatggat gagtttgcaa attagccaac
    15361 tgagcaatga cgttttcacg taccatcgcc gcagcttttg acggtaaatc ggaatgcggg
    15421 cgcgcctcat taacgacgcg ggctgaatcg gcataacgca gccagtggga gacggcaggc
    15481 atatggtcca tgcactgaca gctggcaatg gcggtcatcg cgccacagtt ggaatgacca
    15541 caaatcacaa tgtcagatac ccgaagcgca gcgacggcat actccaccga agcagaaacg
    15601 ccaccgggtt ccggcccgta ggaagggacg atattgcccg cgttgcgaat aacgaacaga
    15661 tcgccaggct cacgttgcgt caccagctca gggaccagac ggctgtcgga gcaggagata
    15721 aaaagtgtgc gcgggctttg ctgtgtcgcc agctgtttaa acaaggcttc ccgcttcgga
    15781 aatgcctcgc gctggaattt aaggaatcca tcaataatct ctttcaccgt taacctctgt
    15841 ctgtctctgg aatgagaggc agactactcg ccgattgtca taaggtaaaa gtctcattta
    15901 tgatgagttc cattggattt acttataggt tgcgaatgct ctctcgacat atcaattatt
    15961 ttcttgccgt ggctgaacat ggcagcttca cccgtgccgc cagtgcgttg cacgtctccc
    16021 aacctgcgct ttcccagcag attcgccagt tagaggagag tttaggcgtg ccgctgtttg
    16081 accgtagcgg gcgaacgatt cgtctcactg atgcaggaga agtctggcga cagtacgcca
    16141 gccgggcgtt acaggaactg ggggcgggta aacgggcgat tcatgatgtt gccgatctga
    16201 cgcgaggatc gctgcgtatc gccgtcaccc ccacctttac gagctacttt atcggcccct
    16261 taatggcgga tttctatgcg cgctatccca gcatcacgct ccagctacag gaaatgtcgc
    16321 aggagaaaat cgaggatatg ctttgccgcg acgagttgga cgttgggatt gccttcgcgc
    16381 ctgtgcattc gccggagctg gaggcaattc ctttactgac agaaagttta gcgttagtcg
    16441 tggcgcaaca tcatccgctg gccgtccatg aacaggtggc gttgagtcgc ttgcatgatg
    16501 aaaaactggt cctgctcagc gcggaatttg ccaccagaga gcaaattgac cactactgcg
    16561 agaaagcggg gctacatcca caggtggtca ttgaggcgaa ctcaattagc gcggttctgg
    16621 agctgattcg ccgcacttcc ctttccacat tgttaccagc agcgattgcc acacaacatg
    16681 acgggcttaa agctatttct cttgccccgc cactactgga gagaacggcg gttttgttgc
    16741 ggcggaaaaa tagctggcag acagccgccg cgaaggcatt tttgcacatg gcgttggata
    16801 aatgcgcggt tgttggcgga aatgaatcac ggtagccgct gacacaggtc
//
LOCUS       DACAOP010000096        16717 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.096, whole genome shotgun sequence.
ACCESSION   DACAOP010000096 DACAOP010000000
VERSION     DACAOP010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16717
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.096"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(98..1264)
                     /gene="dacD"
                     /locus_tag="IT892_003527"
     CDS             complement(98..1264)
                     /gene="dacD"
                     /locus_tag="IT892_003527"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase DacD"
                     /protein_id="HAP3136705.1"
                     /translation="MKRRLIIAASLFVFNLSSGFAAENIPFSPQPPQIQAGSWVLMDY
                     TTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDNPVF
                     VGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYAEKLH
                     LKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRN
                     GLLWDKTMNVDGLKTGHTSGAGFNLIASAVDGQRRLIAVIMGADSAKGREEEARKLLR
                     WGQQNFTTVQILHRGKKVGTERIWYGDKENIALGTEQEFWMVLPKAEIPHIKAKYTLD
                     GKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEGSMFSRLSDYFHHKA"
     gene            1473..2900
                     /gene="sbcB"
                     /locus_tag="IT892_003528"
     CDS             1473..2900
                     /gene="sbcB"
                     /locus_tag="IT892_003528"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="HAP3136706.1"
                     /translation="MMNDGKQQSTFLFHDYETFGTHPALDRPAQFAAIRTDSEFNVIG
                     EPEVFYCKPADDYLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGY
                     NNVRFDDEVTRNVFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDDG
                     LPSFRLEHLTKANGIEHSNAHDAMADVYATIAMAKLVKTRQPRLFDYLFTHRNKHKLM
                     ALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAVIMVDLAGDISPLLELDS
                     DTLRERLYTAKADLGDNAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHCLDNL
                     KILRENPQVREKVVAIFAEAEPFTPSDNVDAQLYNGFFSDADRAAMKIVLETEPRNLP
                     ALDITFVDKRIEKLLFNYRARNFPGTLDYAEQQRWLEHRRQVFTPEFLQGYAEEIQML
                     AQQYADDKEKVALLKALWQYAEEIV"
     gene            complement(2943..3170)
                     /locus_tag="IT892_003529"
     CDS             complement(2943..3170)
                     /locus_tag="IT892_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HAP3136707.1"
                     /translation="MAIKKLDVVTQVCPFPLIEAKAALAEMASGDELVIEFDCTQATE
                     AIPQWAAEEGHAITDYQQIGDAAWSITVQKA"
     gene            complement(3184..4242)
                     /gene="yeeE"
                     /locus_tag="IT892_003530"
     CDS             complement(3184..4242)
                     /gene="yeeE"
                     /locus_tag="IT892_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transport protein YeeE"
                     /protein_id="HAP3136708.1"
                     /translation="MFSMILSGLICGALLGFVMQRGRFCLTGGFRDMYIAKNNRMFYA
                     LLIAISVQSVGVFALIQAGLLTYEAGAFPWLGTVIGGYLFGLGIVLAGGCATGTWYRA
                     GEGLIGSWIALFTYMVMSAVMRSPHASGLNQTLQHYSTEHNSIAETFNLSVWPLVTVL
                     LVITLWVVMKELKKPKLKVATLPPRRTGIAHILFEKRWHPFVTAVLIGLIALLAWPLS
                     EATGRMFGLGITSPTANILQFLVAGDVKYINWGVFLVLGIFVGSFIAAKASREFRVRA
                     ADAQTTLRSGLGGVLMGFGASIAGGCSIGNGLVMTAMMTWQGWIGLVFMILGVWTASW
                     LVYVRPQRKARLATAAAN"
     gene            complement(4421..5779)
                     /gene="plaP"
                     /locus_tag="IT892_003531"
     CDS             complement(4421..5779)
                     /gene="plaP"
                     /locus_tag="IT892_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416518.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PlaP"
                     /protein_id="HAP3136709.1"
                     /translation="MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVS
                     GLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS
                     LLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
                     VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFD
                     GISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEI
                     MLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWR
                     TPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLK
                     DHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYED
                     VA"
     gene            complement(5769..5831)
                     /gene="yoeI"
                     /locus_tag="IT892_003532"
     CDS             complement(5769..5831)
                     /gene="yoeI"
                     /locus_tag="IT892_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YoeI"
                     /protein_id="HAP3136710.1"
                     /translation="MGQFFAYATVITVKENDHVA"
     gene            complement(6046..6975)
                     /locus_tag="IT892_003533"
     CDS             complement(6046..6975)
                     /locus_tag="IT892_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3136711.1"
                     /translation="MKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESD
                     LNIQLLDRSGHRAKFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDT
                     FPFSLLAPLIEAFYQHHSVTRLKFINGVLGGSWDALTQGRADIIVGAMHQPPSSSEFG
                     FSRLGDLEQVFAVAPHHPLAQEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQE
                     AITVFDFKTKLELQISGLGCGYLPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQ
                     TAGLASGWWRDEILANSAIAGVYAKSDDEKSAI"
     gene            complement(7021..7845)
                     /locus_tag="IT892_003534"
     CDS             complement(7021..7845)
                     /locus_tag="IT892_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP3136712.1"
                     /translation="MKKVAIVGLGWLGMPLAMSLSARGWQVTGSKTTQDGVEAARMSG
                     IDSYLLRMEPELVCDSDDLDALMDADALVITLPARRSGPGDEFYLQAVQELVDSALAH
                     RIPRIIFTSSTSVYGDAQGTVKETTPRNPVTNSGRVLEELEDWLHNLPGTSVDILRLA
                     GLVGPGRHPGRFFAGKTAPDGEHGVNLVHLEDVIGAITLLLQAPKGGHIYNICAPAHP
                     ARNVFYPQMARLLGLEPPQFRNSLDSGKGKIIDGSRICNELGFEYQYPDPLVMPLE"
     gene            complement(7928..8182)
                     /gene="yoeB"
                     /locus_tag="IT892_003535"
     CDS             complement(7928..8182)
                     /gene="yoeB"
                     /locus_tag="IT892_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YoeB"
                     /protein_id="HAP3136713.1"
                     /translation="MKLIWSEESWDDYLYWQETDKRIVKKINELIKDTRRTPFEGKGK
                     PEPLKHNLSGFWSRRITEEHRLVYAVTYDSLLIAACRYHY"
     gene            complement(8179..8430)
                     /gene="yefM"
                     /locus_tag="IT892_003536"
     CDS             complement(8179..8430)
                     /gene="yefM"
                     /locus_tag="IT892_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoeB-YefM toxin-antitoxin system antitoxin YefM"
                     /protein_id="HAP3136714.1"
                     /translation="MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEE
                     YNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKDIIE"
     gene            8713..8763
                     /gene="hisL"
                     /locus_tag="IT892_003537"
     CDS             8713..8763
                     /gene="hisL"
                     /locus_tag="IT892_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="his operon leader peptide"
                     /protein_id="HAP3136715.1"
                     /translation="MTRVQFKHHHHHHHPD"
     gene            8909..9808
                     /gene="hisG"
                     /locus_tag="IT892_003538"
     CDS             8909..9808
                     /gene="hisG"
                     /locus_tag="IT892_003538"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HAP3136716.1"
                     /translation="MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAE
                     NMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFG
                     GCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPR
                     AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMDESKQQLIDKLLTRIQ
                     GVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWE
                     TMEKLKALGASSILVLPIEKMME"
     gene            9814..11118
                     /gene="hisD"
                     /locus_tag="IT892_003539"
     CDS             9814..11118
                     /gene="hisD"
                     /locus_tag="IT892_003539"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HAP3136717.1"
                     /translation="MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVK
                     ARGDEALREYSAKFDKTTVTALKVSAEEIAAASERLSDELKQAMAVAVKNIETFHTAQ
                     KLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCKKVVLC
                     SPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAK
                     RQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPAAD
                     MARRVAEAVERQLAELPRAETARQALNASRLIVTNDLAQCVEISNQYGPEHLIIQTRN
                     ARELVDGITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTV
                     QELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA"
     gene            11115..12185
                     /gene="hisC"
                     /locus_tag="IT892_003540"
     CDS             11115..12185
                     /gene="hisC"
                     /locus_tag="IT892_003540"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HAP3136718.1"
                     /translation="MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVE
                     FQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDA
                     ILYCPPTYGMYSVSAETIGVECRTVPTLDNWQLDLQGISDKLDGVKVVYVCSPNNPTG
                     QLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFAL
                     AGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMCERVAQIIAER
                     EYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCL
                     RITVGTREESQRVIDALRAEQV"
     gene            12185..13252
                     /gene="hisB"
                     /locus_tag="IT892_003541"
     CDS             12185..13252
                     /gene="hisB"
                     /locus_tag="IT892_003541"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HAP3136719.1"
                     /translation="MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPELLKLQ
                     KAGYKLVMITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECD
                     CRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGINGLRYDRETLNWPMIGE
                     QLTKRDRYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEI
                     NVKGDLYIDDHHTVEDTGLALGEALKIALGDKRGICRFGFVLPMDECLARCALDISGR
                     PHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFG
                     RTLRQAIRVEGDTLPSSKGVL"
     gene            13252..13842
                     /gene="hisH"
                     /locus_tag="IT892_003542"
     CDS             13252..13842
                     /gene="hisH"
                     /locus_tag="IT892_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HAP3136720.1"
                     /translation="MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFL
                     PGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDED
                     VPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
                     EPFTAAVQKDNFYGVQFHPERSGAAGANLLKNFLEM"
     gene            13842..14579
                     /gene="hisA"
                     /locus_tag="IT892_003543"
     CDS             13842..14579
                     /gene="hisA"
                     /locus_tag="IT892_003543"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HAP3136721.1"
                     /translation="MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAE
                     VLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVG
                     STAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETY
                     LPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTG
                     VRGVIVGRALLEGKFTVKEAIACWQNA"
     gene            14561..15337
                     /gene="hisF"
                     /locus_tag="IT892_003544"
     CDS             14561..15337
                     /gene="hisF"
                     /locus_tag="IT892_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015853929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HAP3136722.1"
                     /translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGA
                     DELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAAKILSFGADKISI
                     NSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETL
                     DWVEEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLE
                     AFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC"
     gene            15331..15939
                     /locus_tag="IT892_003545"
     CDS             15331..15939
                     /locus_tag="IT892_003545"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HAP3136723.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPQALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNITPDCDNDTLLLLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVNDRFELTNEASDLMYHLLVLLQDQGLDLGEVIDNLKNRH"
     gene            complement(15978..>16717)
                     /gene="wbdC"
                     /locus_tag="IT892_003546"
     CDS             complement(15978..>16717)
                     /gene="wbdC"
                     /locus_tag="IT892_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_103927144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,
                     octacis-undecaprenol 3-alpha-mannosyltransferase WbdC"
                     /protein_id="HAP3136724.1"
                     /translation="KLYQPLQERFLASVDCIVASSPNYVASSQTLKKYQDKTVVIPFG
                     LEQHDVQHDPQRVAHWRETVGDNFFLFVGAFRYYKGLHILLDAAERSRLPVVIVGGGP
                     LEAEVRREAQQRGLSNVVFTGMLNDEDKYILFQLCRGVVFPSHLRSEAFGITLLEGAR
                     FARPLISCEIGTGTSFINQDKVSGCVIPPNDSQALVEAMNELWNNEETSNRYGENSRR
                     RFEEMFTADHMIDAYVNLYTTLLESKS"
BASE COUNT         4210 a         4427 c         4260 g         3820 t
ORIGIN      
        1 tttatataca gtataattgc aatattaaaa ccacaaggaa tgagtgttga ttatgcgagc
       61 agactcgcac tcctgccagt ctgctgcaaa agaaaggtca ggccttatgg tggaaataat
      121 cactcaggcg ggaaaacatg ctgccttccc cgacagattc cagggtaacc agcggccagt
      181 gcgccacttg tttatcacgg tcgtaaagtt caatttcccc tacccgctga tgggcgctaa
      241 ttggcgcggt gagttcttta ccatcaaggg tatatttggc tttgatatgt ggaatttcgg
      301 ctttcggtag caccatccag aactcttgtt ccgttcccag ggcgatattt tctttatcgc
      361 cataccagat gcgttccgta ccaacctttt tcccacggtg caaaatttgc accgtagtaa
      421 agttttgttg accccaacgc agtaattttc ttgcctcttc ctcacgacct tttgcgctgt
      481 cagcacccat tatcactgca atgagacgac gctgcccatc tacagccgaa gcaatgaggt
      541 taaaaccggc accagaagta tggcccgttt tcaggccgtc aacattcatg gttttatccc
      601 acaataaccc gttacggttt tgctgggtga taccgttcca ggtgaggctt ttctcactgt
      661 acatatgata aaactcgggc tcgccgtgga tgatagcgcg agaaagcacg gctaaatcat
      721 aagccgagct atgctggcca ggtgcatcca gaccatgcac tgtttcaaaa tgcgtatcct
      781 tgagatgcag cttctcggca tagttgttca tcatttcaac aaactgccgc tgcccaccgg
      841 caatatagtc agccagagca acacaagcgt catttccgga atccacaatt aaaccacggc
      901 ttaaatcacg taccgatacg cgatcgccct ctttcaaaaa catcagtgaa gaaccgacaa
      961 acaccggatt atctttcgcc cacgcatcac gccccacggt gacaatatcg tctggcgtaa
     1021 tgcgatgact atcgatagcg cgatccacga cataacccgt catcagcttt gtcaggctgg
     1081 cgggattgcg ctgttgatgc tcattacccg cggtgagaat ctgaccggtg gtgtaatcca
     1141 tcagtaccca ggacccggct tgaatctgtg gaggctgagg tgaaaaagga atgttttccg
     1201 ccgcaaaacc agacgataag ttaaaaacga acaaagaagc agcaataata agacggcgtt
     1261 tcaacagcaa accctcagga gtttcaaata gctgttcttt ttacggaaat acttatgaac
     1321 tggctggaat aaagtgcaag aaaatgtgac taccctccca tttttatctg acatgatctg
     1381 ttgccactcg ctgtcaaatt atcgcgctaa agctgattag cacggtgata tttgatactc
     1441 tggcagacag cagaaataac ggatttaacc taatgatgaa tgacggtaag caacaatcta
     1501 cctttttgtt tcacgattac gaaacctttg gcacgcaccc cgcgttagat cgccctgcac
     1561 agttcgcagc cattcgcacc gatagcgaat tcaatgtcat cggcgaaccc gaagtctttt
     1621 actgcaagcc cgcggatgac tatttacccc agcctggagc agtattaatt accggtatta
     1681 ccccgcagga agctcgggcg aaaggagaaa acgaagccgc atttgccgcc cgtattcact
     1741 cgctttttac cgtaccgaag acctgtattc tgggctacaa caatgtgcgt ttcgacgatg
     1801 aagtcacacg caacgttttt tatcgtaatt tctacgatcc ttacgcctgg agctggcagc
     1861 atgataactc gcgctgggat ttactggatg ttatgcgtgc ctgttatgcc ctgcgcccgg
     1921 aaggaataaa ctggcctgaa aatgatgacg gtctaccgag ctttcgcctt gagcatttaa
     1981 ccaaagcgaa tggtattgaa catagcaacg cccacgatgc gatggctgat gtgtacgcca
     2041 ctattgcgat ggcaaagctg gtaaaaacgc gtcagccacg cctgtttgat tatctcttta
     2101 cccatcgcaa taaacacaaa ctgatggcgt tgattgatgt tccgcagatg aaacccctgg
     2161 ttcacgtttc cggaatgttt ggggcatggc gcggcaatac cagctgggta gcaccgctgg
     2221 cgtggcatcc tgaaaatcgc aatgccgtaa ttatggtgga tttggcagga gacatttcgc
     2281 cattactgga actggatagc gacacattgc gcgagcgtct atataccgca aaagccgatc
     2341 ttggcgataa cgccgccgtt ccggttaaac tggtgcatat caataaatgt ccggtgctgg
     2401 cccaggcgaa tacgctacgc ccggaagatg ccgaccgact gggaattaat cgtcagcatt
     2461 gcctcgataa cctgaaaatt ctgcgtgaaa atccgcaagt gcgtgaaaaa gtggtggcga
     2521 tattcgcgga agccgaaccg tttacgcctt cagataacgt ggatgcacag ctttataatg
     2581 gctttttcag tgacgccgat cgtgcagcaa tgaaaattgt gcttgaaacc gagccgcgta
     2641 atttaccggc actggatatc acttttgttg ataaacggat tgaaaagctg ttgttcaatt
     2701 atcgggcacg caacttcccg gggacgctgg attatgccga gcagcaacgc tggctggagc
     2761 accgccgcca ggtcttcacg ccagagtttt tacaaggcta tgcagaagag attcagatgc
     2821 tggcgcagca gtatgccgac gataaagaaa aagtggcgct gttaaaagcg ctttggcagt
     2881 acgcggaaga gattgtctaa tgtgaagcct ccgccgctgg tacggcggag gacaatgttg
     2941 agtcaggctt tttgaacggt gatgctccac gctgcatcgc caatctgctg ataatcggtg
     3001 atggcatgtc cttcttctgc cgcccactgt gggattgctt cagttgcctg ggtgcaatca
     3061 aactcaatta ccaactcatc gccgctggcc atttctgcca gtgctgcttt tgcttctatg
     3121 agtggaaacg gacagacctg cgtcaccaca tccagctttt taatcgccat ctttacacct
     3181 tacttaattt gccgcagcag ttgccagtcg cgccttacgc tgcggtcgaa catacacaag
     3241 ccaggacgca gtccagactc cgagaatcat aaatacaagg ccaatccagc cctgccaggt
     3301 catcattgca gtcataacca gtccattacc gatagagcaa ccacctgcaa tactggcacc
     3361 gaagcccatc agtacaccac ctaacccgct acgtaatgtt gtttgtgcat cagctgcgcg
     3421 aacgcggaac tcacggctcg ctttggctgc aataaatgac cccacgaaga tccctaacac
     3481 caggaaaacg ccccagttaa tgtatttcac gtcacccgcg accagaaatt gcagaatatt
     3541 ggccgttggg gaagtgattc ctaacccaaa catgcgtccg gttgcttcac tcaggggcca
     3601 ggctaaaagc gcaatcaaac cgatgagtac agcagtgaca aagggatgcc agcgtttttc
     3661 aaacagaata tgagcgatcc cggttcggcg cggcggtaag gtcgcgactt tgagttttgg
     3721 cttcttcaac tctttcatca ccacccagag cgttatcacc agcaaaacgg taaccaacgg
     3781 ccacacagac aaattaaaag tctcagcaat agagttatgt tcagtactgt agtgctgcaa
     3841 ggtttgattt aaaccactgg cgtgtggaga acgcatcacc gcactcatca ccatataagt
     3901 gaaaagcgcg atccaactgc cgatcaatcc ctcacccgcg cgataccagg tcccggtggc
     3961 acatccaccc gccagaacaa ttcccagccc gaaaagatac ccacctataa cagtaccaag
     4021 ccacgggaac gccccggctt cgtaagtcag taggcccgcc tgaattaacg caaaaacccc
     4081 cacgctttgt accgaaattg caatcagcaa ggcgtaaaac atgcgattat ttttcgcgat
     4141 atacatatcg cgaaaaccac ctgtcaggca aaaacgccca cgctgcatga caaatcccag
     4201 cagagcacca caaattagcc cgcttaatat cattgaaaac ataaattaat taaccagatg
     4261 aatgttaatg gggaaattat tcatgactgg tggaatgcag accaataacc aaattctcta
     4321 aattagaaca aatggttatt aataaggatt tcgataaaaa agaataaaaa aaccggagcc
     4381 aaatgttcat tcgactccgg tttattatta gaaaagatga ttatgctacg tcttcgtact
     4441 gaggaaccgg attacggaaa ctcttggtta cgcaagccag gtaaatcaga ccgatagcag
     4501 cccagatcag acccagaacc attgagcttt cttccaggtt aacccacagc gcaccaacgg
     4561 tcagcgcacc acacatcggc aggaacagat actggaagtg atctttcagc gtcttattac
     4621 gcttctcacg gatccagaac tgcgagatga ccgacaggtt aacgaaggtg aacgccacca
     4681 acgcaccaaa gttaatcagc gccgtagcca ttaccaggtc gaagttgatt gccagcaagg
     4741 caatcgcgcc aaccaggatg atgttcatcg ccggagtacg ccatttcggg tgtacataac
     4801 cgaagaagct tttcgggaac acgccgtcac gacccattac gtacatcaga cgcgccacgc
     4861 ctgcgtgcgc cgccataccg gacgccagta cggtaatggt ggagaagatc agcgcgccaa
     4921 cctggaacgc tttacccgca acgtacagca tgatttcagg ctgtgacgca tccggatctt
     4981 taaagcgaga gatatccggg aagtacagct gcaggaagta agttgcaaag atgaagatca
     5041 tgccgccgat cagcgcggtc aggaaaatcg cacgcgggat cacgcgctct gcatctttgg
     5101 tttcttccga caggttgctg atgccgtcaa aaccggtaaa ggagaagcac aggattgtcg
     5161 ccccggtaat catcgggata acatgcgcat caccagacca gaacggacga gtgctcgcca
     5221 gcgtaccagc gccttcacct tcaaatacac cataaacaac catgcccaga atcaccgcga
     5281 tcagcactac ctgcaacacg acgattacag tgttgaagtt cgctacggat ttcagactac
     5341 gcaggttaaa ggcggtcata aaggccacca gcgccaccac aaacatccac gatggaatgg
     5401 aaggcaccag agcttcaaaa tagattttcg ccaacagaat gttgatcatc ggcgcgaaca
     5461 gatagtcgag cagagaagac caacccacca taaagccgac agtcgggcta atggatttct
     5521 gggcgtaagt gtatgcagag ccagcagaag gatagcggcg aaccagcttc ccgtagctca
     5581 gagccgtaaa caggatcgca atcaatgcga acgcataggc tgtcggcaca tgaccatccg
     5641 tgaggcctga aacgatacca aatgtatcaa acagcgtcat cggctgcata taggctagac
     5701 ccatcattac aaccggaact aacgtaagcg ttttacgcaa ttccacgcga gaggtgtttg
     5761 gagtaacgtt atgcgacatg gtcattctcc tttacggtga taaccgtcgc gtaagcaaaa
     5821 aattgcccca tttttttgga ttcctcagcg acaacaactg tcgattttta gtaaatatct
     5881 atccggtacg aagcccggcc tcttggtatg aatgattggt ttgaagcaaa aaataaccga
     5941 cgctaattaa acgtcggttt ttagtcattt tttgacagcg gcgcattgtg cctaaatggg
     6001 ggggaaatga caagagaatg agaggcttgt cataataatt tttctttaaa tggctgattt
     6061 ttcgtcatca gattttgcat aaacaccggc gatcgcacta tttgctaaaa tttcatcccg
     6121 ccaccagccg ctggcaagcc ctgcggtctg ttcattccag ccaatccaga cgggttcaaa
     6181 gagagtttgg gcgaccactt tcttctcgat taacgcgcca ctatcgagaa aacgttgcgc
     6241 cagataccgt ggtaaatagc cgcagccaag gccgctaatt tgcagctcca gtttggtttt
     6301 aaaatcgaaa acggtaatgg cttcttgttc gtcgagaagt tgtgaggccg tagaagcgcc
     6361 tgcctgcgca gtgtccccca ccacaatcgc ccgatatcgt ttaatgatac gacggtttaa
     6421 cggttcttct tcctgggcta acggatgatg aggcgcgacc gcaaagactt gttcaagatc
     6481 gcccaaccgc gagaaaccaa actcactgga agatggtggc tgatgcatcg cgccaacgat
     6541 aatatccgct cgcccctgag tcagggcatc ccaggaacca ccgagtacac cattgataaa
     6601 cttcaggcgc gtcacgctat gatgttgata aaaagcttca atcagtggcg caagcagaga
     6661 aaaaggaaac gtgtcgtcca cgccaatcac cagctcgttt tcccagcctt catgcagttt
     6721 gatcgcctgc ttttccagtt cccgcacggt atgcagaact tcccgcccct tctctaataa
     6781 catttttccg gtacgggtga atttagcgcg gtgaccgcta cgatcaagca attgaatatt
     6841 aaggtcgctt tccagcttgt gaacggtgta actcagagcg gacggcgtct tgtagagttt
     6901 ggccgacgcc gccgcaaaac tgccttcttt ttctaaggca tcgaggatca tcaacacatc
     6961 cagcagtggt ttcatacacg cccccttgca gtgcatgcgg cgtcctgctg gcgtgatcgt
     7021 ttactccagc ggcattacca gcggatcggg atactggtat tcaaatccca gttcattaca
     7081 aatccgactg ccatcaataa tcttaccttt gccgctgtcc agactatttc tgaactgcgg
     7141 aggttccagc cccagtaaac gggccatctg cggatagaaa acattacgcg cagggtgagc
     7201 tggcgcacat atattataga tgtgtccgcc tttaggtgcc tgtaacaaca gagtgatagc
     7261 gccaataaca tcttctaaat ggactaaatt aacaccatgt tcaccatcag gcgcggtttt
     7321 tccggcaaag aagcgtccgg gatgacgtcc cggtccgacc agtcccgcaa gacgcaggat
     7381 atcgaccgaa gtaccaggta aattgtgcag ccagtcttcg agttcttcta atactcgtcc
     7441 actgttggtt accggattac gcggggtggt ttctttcacc gtgccttgcg cgtcgccata
     7501 gacagatgtt gagctggtaa aaataatgcg gggaatacga tgggccagcg cgctatccac
     7561 taactcttgt accgcttgta aatagaactc atcgccgggg ccgctacgac gtgccggaag
     7621 cgtaatgacc agcgcatcgg catccatcag ggcatccaga tcgtcagaat cgcaaactaa
     7681 ctcaggctcc atgcgaagca gatagctatc aatgccactc attcgggctg cttcgacacc
     7741 atcttgtgtg gttttactcc cggtgacttg ccagcctcgc gctgaaagtg acatcgccag
     7801 cggcatgcct aaccacccta acccgacaat tgcgaccttt ttcatccgtt atctcctgat
     7861 acaccttaga tctataaggc tacgctagcg tatcaaaact gacaattcat tctatgaatg
     7921 aatctgttca ataatgataa cgacatgctg caatgagcag tgaatcgtag gtaaccgcgt
     7981 ataccagacg gtgctcctct gtaatgcgtc gagaccagaa acctgacaaa ttatgtttca
     8041 ggggttctgg cttcccctta ccttcaaatg gcgttctgcg ggtatctttg ataagttcat
     8101 tgatcttttt aacaattcgc ttatctgttt cctgccagta cagataatca tcccatgatt
     8161 cctcagacca gattagtttc actcaataat gtccttttct gttcctttgc ctgatttcag
     8221 gctatcgatt gagtccatca atctccgggc gttagcgggg gaacgcagta gataagccgt
     8281 ctcttccagc gagttgtatt cttcgagtga catcagaaca caagcctctc cattctgacg
     8341 agtaataagg atcggggcat gatcttcaac ggctttcatc attgttgccg acaaattctg
     8401 acgcgcttcg ctgtagctaa ttgtacgcat gtcaatctcc tcttttgtac agttcattgt
     8461 acaatgatgg gcgttaatta actatttatt aattagtttg tagatcaagg tattgtcagt
     8521 gagacgaaaa tccaggcttc gctatttttg gtgccgtcag cttagaggac agtcctctta
     8581 gccccctcct ttccccgctc attcattaaa caaatccatc gccataaaat atataaaaaa
     8641 gcccttgctt tctaacgtga aagtggttta ggttaaaaga catcagttga ataaacattc
     8701 acagagactt ttatgacacg cgttcaattt aaacaccacc atcatcacca tcatcctgac
     8761 tagtctttca ggcgatgtgt gctggaagac attcagatct tccagtggtg catgaacgca
     8821 tgagaaagcc cccggaagat caccttccgg gggctttttt attgcgcggt tgataacggt
     8881 tcagacaggt ttaaagagga ataagaaaat gacagacaac actcgtttac gcatagctat
     8941 gcagaaatcc ggccgtttaa gtgatgactc acgcgaattg ctggcgcgct gtggcattaa
     9001 aatcaatctt cacacccagc gcctgatcgc gatggcagaa aacatgccga ttgatattct
     9061 gcgcgtgcgt gacgacgaca ttcccggtct ggtaatggac ggcgtggttg acctcgggat
     9121 tatcggcgaa aacgtgctgg aagaagagct gcttaaccgc cgcgcccagg gtgaagatcc
     9181 acgctacttt accctgcgtc gtctggattt cggcggctgc cgactttcac tggcaacgcc
     9241 ggttgatgaa gcctgggatg gcccgctctc cttaaacggt aaacgtatcg ccacctctta
     9301 tcctcacctg ctcaagcgtt atctcgacca gaaaggtatc tcttttaaat cctgcttact
     9361 gaacggttct gttgaagtcg ccccgcgtgc cggactggcg gatgcgattt gcgatctggt
     9421 ttccaccggt gccacgctgg aagctaacgg cctgcgcgaa gtcgaagtta tctatcgctc
     9481 gaaagcctgc ctgatacaac gcgatggcga aatggatgaa tctaaacagc aactgatcga
     9541 caagctgctg acccgtattc agggtgttat ccaggcgcgc gaatcaaaat acatcatgat
     9601 gcacgcaccg accgaacgtc tggatgaagt catcgccctg ctgccaggtg ccgaacgccc
     9661 aactattctg ccgctggcgg gtgatcaaca gcgcgtagcg atgcacatgg tcagtagcga
     9721 aaccctgttc tgggaaacga tggaaaaact gaaagcgctg ggtgccagtt cgattctggt
     9781 cctgccgatt gagaagatga tggagtgatc gccatgagct ttaacacaat cattgactgg
     9841 aatagctgta ctgcggagca acaacgccag ctgttaatgc gcccggcgat ctccgcttct
     9901 gaaagcatta cccgcactgt taacgatatt ctcgataacg tgaaagcacg cggcgatgag
     9961 gccctgcggg aatacagcgc gaagtttgat aaaaccacgg ttaccgcact gaaggtgtct
    10021 gctgaggaaa ttgccgccgc tagcgaacgc ctgagcgacg agctaaaaca ggcgatggcg
    10081 gtggcagtga agaatattga aaccttccac actgcgcaaa aactgccgcc ggtagatgta
    10141 gaaacgcagc caggcgtgcg ttgccagcag gtcacgcgcc cggtcgcttc agttgggttg
    10201 tatattcctg gcggctccgc cccgctcttc tcaacggtat taatgctggc gactccggcg
    10261 cgtattgcgg gctgtaaaaa agtggtgctg tgctcaccgc cgccgattgc cgatgagatc
    10321 ctttatgcgg cgcagctgtg cggtgtgcag gacgtgttta acgtcggcgg cgcacaggcc
    10381 attgccgcac tggcgtttgg tacggaatct gtgccgaaag tggacaaaat cttcgggccg
    10441 ggcaacgcct ttgtcaccga agcgaaacgt caggtgagcc agcgtctgga cggtgcggcg
    10501 atcgatatgc ccgcaggccc gtcggaagtg ttggtcattg ccgacagtgg cgcaacgccg
    10561 gatttcgtgg cttctgattt gctttctcag gctgaacacg gcccggactc acaggtgatt
    10621 ttactgacgc ccgctgctga tatggcgcgt cgcgttgccg aggccgtcga acgccagttg
    10681 gcagaactgc cgcgtgccga aaccgcccgc caggcactga acgccagccg cctgatcgtg
    10741 accaacgatt tagcacagtg cgtagagatc tccaaccagt acggcccgga gcacctgatc
    10801 attcagaccc gcaacgcccg cgaactggtc gatggcatta ccagtgccgg ttcggtattt
    10861 cttggtgact ggtcaccgga atcggcaggt gattacgcct ccggcaccaa ccacgttctg
    10921 ccgacttacg gttacaccgc cacctgttcc agcctcgggc tggcagattt ccagaagcgc
    10981 atgaccgtgc aggaactctc gaaagaaggt ttctccgcgc tggcttcgac cattgaaaca
    11041 ttggccgccg ccgagcgcct gactgcccac aaaaatgccg ttactttgcg tgttaacgcc
    11101 cttaaggagc aagcatgagc accgtgacta ttaccgattt agcgcgtgaa aacgtccgca
    11161 acctgacgcc gtatcagtcg gcgcgtcgtc tgggcggtaa tggcgacgtc tggctgaacg
    11221 ccaacgaata tcccacagcc gtggagtttc agcttactca gcaaacgctc aaccgctacc
    11281 cggaatgtca gccgaaagcg gtgattgaaa attacgcgca gtatgcaggc gtaaaaccgg
    11341 agcaggtgct ggtcagccgt ggcgcggacg aaggtattga actactgatt cgcgcttttt
    11401 gcgaaccagg taaagacgcc atcctctact gcccgccaac gtacggcatg tacagcgtca
    11461 gcgctgaaac cattggcgtc gagtgccgca cagtgccgac gctggacaac tggcaactgg
    11521 acttacaggg catttccgac aagctggacg gcgtaaaagt ggtctatgtt tgcagcccca
    11581 acaacccgac cgggcaactg atcaacccgc aggattttcg cactctgctg gagttaaccc
    11641 gcggtaaagc gattgtggtt gccgatgaag cctatatcga gttttgcccg caggcatcgc
    11701 tggctggctg gctggcggaa tatccgcacc tggctatttt gcgcacactg tcgaaagctt
    11761 ttgctctggc gggccttcgt tgcggattta cgctggcaaa cgaagaagtc atcaacctgc
    11821 tgatgaaagt gattgccccc tacccgctct cgacgccggt tgccgacatt gcggcccagg
    11881 cgttaagccc gcaggggatc gtcgccatgt gtgagcgggt ggcgcaaatt attgcagaac
    11941 gcgaatacct gattgccgca ctgaaagaga tcccctgcgt ggagcaggtt ttcgactctg
    12001 aaaccaacta cattctggcg cgctttaaag cctccagtgc agtgtttaaa tctttgtggg
    12061 atcagggcat tatcttacgt gatcagaata aacaaccctc tttaagcggc tgcctgcgaa
    12121 ttaccgtcgg aacccgtgaa gaaagccagc gcgtcattga cgccttacgt gcggagcaag
    12181 tttaatgagt cagaagtatc tttttatcga tcgcgatgga accctgatta gcgaaccgcc
    12241 gagtgatttt caggtggacc gttttgacaa actcgccttt gaaccgggcg tgatcccgga
    12301 gctactgaag ctgcaaaaag cgggctacaa gctggtgatg atcactaatc aggatggtct
    12361 gggaacacaa agtttcccgc aggcggattt tgatggcccg cacaacctga tgatgcagat
    12421 cttcacctcg caaggcgtgc agtttgatga agtgctgatt tgtccgcacc tgcccgccga
    12481 tgagtgcgac tgccgtaagc cgaaagtaaa actggtggag cgttatcttg ctgagcaagc
    12541 gatggatcgt gccaatagtt atgtgattgg cgatcgcgcg accgacattc aactggcgga
    12601 aaacatgggc attaatggtt tacgctacga ccgcgaaacc ctgaactggc cgatgattgg
    12661 tgagcaactc actaaacgag accgttacgc ccatgtagtg cgcaacacca aagagacgca
    12721 aattgacgtc caggtgtggc tggatcgcga aggtggcagc aagattaaca ccggcgttgg
    12781 cttctttgat catatgctgg atcagatcgc cacccacggc ggtttccgca tggaaatcaa
    12841 cgtcaaaggc gacctctata tcgacgatca ccacaccgtc gaagataccg gcctggcgct
    12901 gggcgaagcg ttaaaaattg ccctcggcga taaacgcggt atttgtcgct ttggttttgt
    12961 gctgccgatg gacgaatgcc ttgcccgctg cgcgctggat atctctggtc gcccgcacct
    13021 ggaatataaa gccgagttta cctaccagcg cgtgggcgat ctcagcaccg agatgatcga
    13081 gcacttcttc cgttcactct cttacaccat gggcgtgacg ttgcacctga aaaccaaagg
    13141 taaaaacgat caccaccgtg tagagagcct gttcaaagcc tttggtcgca ccctgcgcca
    13201 ggccatccgc gtggaaggcg acaccctgcc ctcgtcgaaa ggagtgctgt aatgaacgtg
    13261 gtgatccttg ataccggctg cgccaatttg aactcggtga agtcagccat tgcgcgtcac
    13321 ggttatgaac ccaaagtcag ccgtgacccg gacgtcgtgt tgctggccga taaactattt
    13381 ttacccggcg ttggcaccgc acaagcagcg atggatcagg tccgtgagcg cgagctgttt
    13441 gatctcatca aagcctgtac ccaaccggtg ctgggcatct gcttagggat gcaactgctg
    13501 gggcggcgca gtgaagagag caacggcgtc gatctgctgg gcatcatcga cgaagacgtg
    13561 ccgaaaatga ccgactttgg tctgccgctg ccgcatatgg gctggaaccg cgtttacccg
    13621 caggcaggca accgcctgtt tcaggggatt gaagacggcg cgtactttta ctttgttcac
    13681 agctacgcaa tgccagtcaa tccgtggacc atcgcccagt gtaactacgg cgaaccgttc
    13741 accgcggcgg tacaaaaaga taacttctac ggcgtgcagt tccacccgga gcgttctggt
    13801 gctgctggcg ctaatttgct gaaaaacttc ctggagatgt gatgattatt ccggcattag
    13861 atttaatcga cggcaccgtg gtgcgtctcc atcagggcga ttacggcaaa cagcgcgatt
    13921 acggtaacga cccgctgcca cgcttacagg attacgccgc gcagggtgcc gaagtgttgc
    13981 atctggtgga tctgaccggg gcaaaagatc cggctaaacg tcaaatcccg ctgattaaaa
    14041 ccctggtcgc gggcgttaac gttccggtgc aggttggcgg cggcgtgcgt agcgaagaag
    14101 acgtggcggc gttactggaa gcgggcgttg cgcgcgtggt ggttggctcc accgcggtga
    14161 aatcaccaga aatggtgaaa ggctggtttg aacgcttcgg tgccgatgcc ttagtgctgg
    14221 cgctggatgt ccgtattgac gagcaaggca acaagcaggt ggcagtcagc ggctggcaag
    14281 agaactcggg cgtttcactg gaacaactgg tggaaaccta tctgcccgtc ggcctgaaac
    14341 atgtgctgtg taccgatatc tcgcgcgacg gcacgctggc aggttctaac gtctctttat
    14401 atgaagaagt gtgcgccaga tatccgcagg tggcatttca gtcttccggc ggtattggcg
    14461 acattgatga tgtcgcggcc ctgcgtggta ctggcgtgcg cggcgtaata gttggtcgtg
    14521 cattactgga aggtaaattc accgtgaagg aggccatcgc atgctggcaa aacgcataat
    14581 cccatgtctc gacgttcgtg atggtcaggt ggtgaaaggc gtacagtttc gcaaccatga
    14641 aatcattggc gatattgtac cgctggcaaa acgctacgct gaagaaggtg cagacgaact
    14701 ggtgttctac gatatcaccg cttccagcga tggccgtgtg gtagataaaa gctgggtatc
    14761 tcgcgtggcg gaagtgatcg acattccgtt ctgtgtggcg ggtgggatta agtctctgga
    14821 agatgccgcg aaaattcttt cctttggcgc ggataaaatt tccatcaact ctcctgcgct
    14881 ggcggacccg acgttaatta ctcgcctggc ggatcgcttt ggcgtgcagt gtattgtggt
    14941 cggtattgat acctggtacg acgctgaaac cggtaaatat catgtgaatc aatataccgg
    15001 cgatgaaagc cgcacccgcg tcactcagtg ggaaacgctc gactgggtag aggaagtgca
    15061 aaaacgcggt gccggagaaa tcgtcctcaa catgatgaat caggacggcg tgcgtaacgg
    15121 ttacgaccta gaacaactga aaaaagtgcg tgaagtttgc cacgtcccgc tgattgcctc
    15181 cggtggcgcg ggcaccatgg aacacttcct cgaagccttc cgcgatgccg acgttgacgg
    15241 cgcgctggca gcttccgtat tccacaaaca aataatcaat attggtgaat taaaagcgta
    15301 cctggcaaca cagggcgtgg agatcaggat atgttaacag aacaacaacg tcgcgaactg
    15361 gactgggaaa aaaccgacgg acttatgccg gtgattgtgc aacacgcggt atccggtgaa
    15421 gtgttaatgc tgggctatat gaacccgcaa gccctggaca aaaccatcga aagcggcaaa
    15481 gtcaccttct tctcgcgcac taaacagcga ctgtggacca aaggcgaaac gtcgggcaat
    15541 ttcctcaacg tagtaaatat tacgccggac tgcgacaacg acacgttact gttgctggcg
    15601 aatcccatcg gcccgacctg ccacaaaggc accagcagct gcttcggcga caccgctcac
    15661 cagtggctgt tcctgtatca actggaacaa ctgctcgccg aacgtaaatc tgccgacccg
    15721 gaaacctcct ataccgccaa actgtatgcc agcggcacca aacgcattgc gcagaaagtg
    15781 ggcgaagaag gggtggaaac cgcactggcc gcgacggtaa atgaccgctt tgagctgacc
    15841 aacgaggcat ctgatttgat gtatcacctg ctggtgctgt tgcaggatca ggggctggat
    15901 ctcggagaag tgattgataa tctgaagaat cggcattaac gcgttggccc ccgcagcaac
    15961 ggcgggggta gcagctctca ggatttgctt tccagcaatg tagtgtagag attgacatag
    16021 gcgtcaatca tatggtcggc agtaaacatc tcttcaaaac gacgacgcga gttttcgcca
    16081 tagcggttgg aggtttcctc gttattccag agctcattca tcgcctccac cagcgcctgg
    16141 ctatcattcg gcggaatcac gcaaccactc actttgtcct ggttaatgaa agaggtacct
    16201 gtaccgatct cgcaagagat cagcggcctt gcaaagcgtg cgccttccaa taacgtaatg
    16261 ccaaacgcct cagagcgcag atgcgagggg aataccacgc cccggcagag ctggaagaga
    16321 atgtacttat cttcgtcgtt gagcatgccg gtaaacacca cattgctcag cccgcgttgc
    16381 tgcgcctcac gccgcacttc cgcctccagc ggcccgcccc cgacgatcac caccggcagc
    16441 cggctacgct cggcggcatc cagcagaatg tgcagccctt tgtagtagcg gaaagcgccg
    16501 acgaagagga agaagttatc gccgacggtt tcccgccagt gcgccacccg ctgcggatcg
    16561 tgctgcacgt catgctgctc cagaccaaac gggatcacca cggttttatc ctgatatttt
    16621 ttcagggtct ggctggaggc cacgtagttg ggcgacgagg cgacgatgca gtctacgctg
    16681 gcgaggaatc gctcctgcag cggctggtac aacttca
//
LOCUS       DACAOP010000097        16499 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.097, whole genome shotgun sequence.
ACCESSION   DACAOP010000097 DACAOP010000000
VERSION     DACAOP010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16499
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.097"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..239
                     /locus_tag="IT892_003547"
     CDS             <1..239
                     /locus_tag="IT892_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136725.1"
                     /translation="DEEKKEIVNKLPGYVVKIFEEKIDNELKIRTRMMETLRDGKINI
                     YDYINEKQLEKLNPPQDLRSAIEKIGWKNRPITA"
     gene            complement(296..1300)
                     /gene="argF"
                     /locus_tag="IT892_003548"
     CDS             complement(296..1300)
                     /gene="argF"
                     /locus_tag="IT892_003548"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000012906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAP3136726.1"
                     /translation="MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLT
                     GKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYD
                     GIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTED
                     VAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNNKMMQLTGNPEVKFLHCLP
                     AFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSN
                     "
     gene            1462..1878
                     /gene="rraB"
                     /locus_tag="IT892_003549"
     CDS             1462..1878
                     /gene="rraB"
                     /locus_tag="IT892_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HAP3136727.1"
                     /translation="MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLE
                     TLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAE
                     KFDVEYDGWGTYFEDPNGEDGDDEDFVDEEDDGVRH"
     gene            complement(1924..2427)
                     /locus_tag="IT892_003550"
     CDS             complement(1924..2427)
                     /locus_tag="IT892_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP3136728.1"
                     /translation="MNVVASPALRLRKLTVADNPAIASVIRQVSAEYGLTADKGYTVA
                     DPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGK
                     GLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCE
                     VRMLREL"
     gene            2620..3807
                     /locus_tag="IT892_003551"
     CDS             2620..3807
                     /locus_tag="IT892_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF898 family protein"
                     /protein_id="HAP3136729.1"
                     /translation="MNGVNVGKDNPRHAFVFTGKGGEYFLICLVNFLLTIITLGIYGP
                     WALVKCRRYICQHVTLKGQPFSYKGTGGAIFVSMLLIMVVYFLSISCVAGQHFVLAFL
                     LFALLICGIPCMAVKSLQYQANMTSLNGIRFGFNCSMLRAWWVMLGLPVLLALAFWLV
                     LYLIAQVTTSIGGLFFNLVVLSLLSVIGLGVINGITYSKWMPLLGNNATFGVHQFSIK
                     VNVKECIKGCMLAILTMVPFIIVIGIMIAPVFQQLIMMSMLGQSEAGGELILQYYPQI
                     MASYFLYFVAILVFASYLYVTLRSLFLNNLTLANGTIRFHSSVTTFGMLLRMLAVLMG
                     SSITCGLAYPWLKMWMVSWIANNTHVQGDLDSLELTNDDKPQDSGPLMWISRGIMPYV
                     PFI"
     gene            complement(3859..6714)
                     /gene="valS"
                     /locus_tag="IT892_003552"
     CDS             complement(3859..6714)
                     /gene="valS"
                     /locus_tag="IT892_003552"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAP3136730.1"
                     /translation="MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNV
                     TGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTR
                     HDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
                     YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLV
                     VATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCV
                     KITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQK
                     LERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKP
                     AVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRN
                     EEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSG
                     FDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPL
                     DMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALAST
                     GRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFN
                     QTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLV
                     TVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTE
                     WLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVL
                     PADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIDGEISRIENKLANEG
                     FVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL"
     gene            complement(6714..7157)
                     /gene="holC"
                     /locus_tag="IT892_003553"
     CDS             complement(6714..7157)
                     /gene="holC"
                     /locus_tag="IT892_003553"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HAP3136731.1"
                     /translation="MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACE
                     DEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTS
                     FADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK"
     gene            complement(7511..9022)
                     /gene="pepA"
                     /locus_tag="IT892_003554"
     CDS             complement(7511..9022)
                     /gene="pepA"
                     /locus_tag="IT892_003554"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HAP3136732.1"
                     /translation="MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYIS
                     ALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLND
                     TGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
                     VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNV
                     ITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDS
                     GGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRP
                     GDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHI
                     TGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITA
                     GCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE"
     gene            9289..10389
                     /gene="lptF"
                     /locus_tag="IT892_003555"
     CDS             9289..10389
                     /gene="lptF"
                     /locus_tag="IT892_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HAP3136733.1"
                     /translation="MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIP
                     ANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAA
                     MILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
                     IESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTAL
                     LRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTV
                     FMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTV
                     NLIYLALAIVLNLWDTVPVRRLRASFSRKGAV"
     gene            10389..11471
                     /gene="lptG"
                     /locus_tag="IT892_003556"
     CDS             10389..11471
                     /gene="lptG"
                     /locus_tag="IT892_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313266.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HAP3136734.1"
                     /translation="MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQ
                     GSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQV
                     ALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
                     VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPK
                     QITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMW
                     SKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYG
                     IPPIIGALLPSASFFLISLWLLMRKS"
     gene            complement(11632..13134)
                     /locus_tag="IT892_003557"
     CDS             complement(11632..13134)
                     /locus_tag="IT892_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HAP3136735.1"
                     /translation="MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLA
                     ESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLTRLKNIGVNDWQPHANPVVVWDIFG
                     EKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQY
                     IGDNAKSFQNQYGNISSASVGAIQRGLLTLEQQGATHFFGEPMLDIKDWMRTDANGKG
                     VINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAP
                     QVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAV
                     KAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTE
                     DERNGLINHSPVYGKYEDDVDRESAYEMLQKGVQASTEQQNNPAVKGKEVAVDDGILG
                     GLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR"
     gene            complement(13262..14281)
                     /gene="ahr"
                     /locus_tag="IT892_003558"
     CDS             complement(13262..14281)
                     /gene="ahr"
                     /locus_tag="IT892_003558"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase Ahr"
                     /protein_id="HAP3136736.1"
                     /translation="MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSD
                     LSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDAC
                     ISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKP
                     LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVN
                     SRDPQALKALSGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLI
                     AGDRSISGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVV
                     LKADF"
     gene            14477..14561
                     /locus_tag="IT892_003559"
     tRNA            14477..14561
                     /locus_tag="IT892_003559"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14511..14513,aa:Leu,seq:caa)
     gene            14726..15988
                     /locus_tag="IT892_003560"
     CDS             14726..15988
                     /locus_tag="IT892_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012989088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HAP3136737.1"
                     /translation="MKLNARQIETAKPKEKAYKMADGGGLYLEVSPKGSKYWRMKYRR
                     PSDKKEDRLAFGVYPTVTLAEARGKRDAAKKLLSQGIDPKAEQKGAQAEIEGAYLFET
                     IARQWHASNLTWSEDHSRRVLLTLEQYIFPSIGQIDARTLRTSQLLNPIKAVDTAGKH
                     DVAQRLMQRVTAIMRFGVQNDLLESNPACDMAGALLSVKATHHPALPPKRIPELLERL
                     SRYKGRLMTRLAVELTLLTFIRSSEMRFARWSEVNFERSEWTIPGIRKPIPGVKHSER
                     GMKMKTEHIVPLSKQAFDIFKRLHALSGKGEVIFPSDHDPKKVMSENTVNNALRVMGY
                     DTKTEVCGHGFRTMARGALSESKLWNDDAIERQLSHVERKNVKGSYMHTSEYLEERRL
                     MLQWWADYIDANKNGSVTPYDFARMHGK"
     gene            16018..>16499
                     /locus_tag="IT892_003561"
     CDS             16018..>16499
                     /locus_tag="IT892_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136738.1"
                     /translation="MNNTQFDNNLFYFNRLTYITPHEVALAMNGFDYDTENDELTEVQ
                     LKEVIRLRKAITRNLQLINEYKNVSATQKVEANLLLTAAYIFQREGIVPVEIKERIEN
                     ALRQQVKNKDWSDILMTLGGSELYEVGKKLRSNGRGQYRKDDEDNYSCKLIYLLIELL
                     "
BASE COUNT         3958 a         4173 c         4154 g         4214 t
ORIGIN      
        1 gtgatgaaga aaaaaaagaa attgtaaata aacttccggg ttatgtcgtt aagatttttg
       61 aagaaaagat cgataatgaa ttaaaaatta gaacaagaat gatggaaacc ctgcgggatg
      121 ggaaaatcaa tatatatgat tatattaatg aaaaacagtt agaaaaatta aatccaccgc
      181 aagatttacg ttctgcaata gaaaaaattg ggtggaagaa tagacctatc actgcataaa
      241 ataatgtgat gccgggatag ttttgtattt cccggcatct ttatagcgat atcaattagt
      301 tactgagcgt cgcgaccatc accgctttga tggtatgcat gcggttttcc gcctgatcaa
      361 atacaatgct ggcggcagat tcgaagacct catcagtcac ttccattccg ccatgtaggc
      421 caaactcttc cgccattttc ttaccaagcg tcgtctggtc gtcatgaaac gcgggcaggc
      481 agtggaggaa tttgacctcc gggttaccgg tcaactgcat catcttgtta ttcacctgat
      541 aatcacgcag caatgcaatc cgttccgccc atttctcttt tgcttcaccc atcgacaccc
      601 atacatcggt atagataaag tcagcacctt ctactccttt ggctacatct tccgtcagcg
      661 taatattccc gccattttgc tgtgccaggg cgcggcattc cgtaaccagc gcagcttccg
      721 gccagcatgc ctgtggcgcg accagacgca aatccagacc ggtaagcgcc gcagcttcga
      781 gcatcgaatt gcccatgttg ttacgtgcgt cacctgcata gaccagcgtc atttcgttga
      841 atgctttacc gggcaaatgc tcctgcatgg tgagaagatc cgccagcagc tgcgtggggt
      901 gaaactcatt ggtcaggccg ttccataccg gcacgccagc gtattccgcc agtgtttcga
      961 caatctcctg accatagccg cgatactgaa taccgtcata catgcgaccc agcacgcggg
     1021 cagtgtcttt aatcgactct ttatgaccaa tctggctgcc gcttgggcca agataagtaa
     1081 cgcgagcccc ctggtcatat gcggcaactt cgaaagagca tcgggtacgg gtcgagtctt
     1141 tttcgaagat gagcgcgatg tttttaccag tgagtttggc ttcttcttta ccgcttttct
     1201 tatcggcttt cagcttcgcg gctaactgca acaggctgtt gagttcagct ggcgtgaaat
     1261 cgagtaattt taggaaatgc ttatgataaa acccggacat agatccctcc tgtggctaac
     1321 gcctcaatga attaaaattc aatttatatg gatgattatt catttgcaag cctaaagcat
     1381 aaatctttgt cacaaaggtg gaggcaatgt cagtggtgtg tgacaataag agtatcggca
     1441 ggacattaag aggaatgagc catggcaaac ccggaacaac tggaagaaca gcgtgaagaa
     1501 acacgtttga ttattgaaga attactggaa gatggcagcg atccggacgc gctgtacacc
     1561 atcgaacacc atctttccgc agacgatctg gaaaccctgg aaaaagcagc agttgaagcg
     1621 tttaaactcg gttacgaagt gaccgatcca gaagagctgg aagttgaaga tggtgatatc
     1681 gtgatttgct gcgacatcct cagcgagtgc gcgttgaatg ccgatctgat cgatgcccag
     1741 gttgaacaac tgatgacgct ggcggagaaa tttgacgttg agtacgacgg ttggggcact
     1801 tactttgaag atcccaacgg cgaagacggc gacgatgaag attttgtcga cgaagaagat
     1861 gacggggttc gccactaatt aattgattaa aatgcccgat agcacacact agcgggcatt
     1921 tttttagagt tcgcgtagca tccgcacttc acaatcgaca tggcccgtgc agccaagcgc
     1981 atagtcgata tgctcaaagc ccaaatgctc ataaagcgca atggcttcct ttaaaaaagc
     2041 ggtcgtttcc agatagcagc gtttgaagcc catctctcgt gcctgctcca tcgccattaa
     2101 ggccagtttt ttcgccagcc ctttaccgcg aatagccgga agaaaataca tcttttgcag
     2161 ttcgcaaatg tccgattcac tacctgctaa tggcgctatc ccaccgccgc cgaccacttc
     2221 accctcgtac tcaaccaccc aatatgcatg gccaggctga ctatacactt gatacaactc
     2281 gtcaaggttc ggatcggcga cggtgtagcc tttatcagcg gtaagaccgt attcggcgga
     2341 tacctgacga atgacgctgg cgatagcagg attatcggcg acggtaagtt tgcgcaaacg
     2401 gagtgcggga gaagcgacaa cattcatagc atagctcaat ttcaaatgta tgatttatag
     2461 ctcactttaa taccaccctc gcttaggtgg tgcaacaaga agataaatca gaaaatatta
     2521 agcatatatc gcttagataa agcgtattct agatggtcca gtagcaattg actggaatta
     2581 ttatctatat gaatggaatt tattttaggg atatagttca tgaatggtgt aaacgtcggg
     2641 aaagataatc ctcgtcacgc atttgttttt acaggcaaag gtggtgagta ttttcttatt
     2701 tgtcttgtga attttttact gacaattatt actctgggaa tatatggacc gtgggcattg
     2761 gtgaaatgcc gtcgttatat ttgtcagcat gtgacactca aggggcaacc atttagttat
     2821 aagggaacag gtggtgccat ttttgttagc atgttactta ttatggtcgt ttattttctc
     2881 agtatttctt gtgttgcagg ccaacacttt gttcttgctt ttctcctgtt tgctctcttg
     2941 atctgcggta ttccttgtat ggcagtgaag agtctgcagt atcaggcgaa catgacctcg
     3001 ctcaatggta ttcgctttgg ctttaactgc tcaatgctcc gtgcatggtg ggttatgtta
     3061 ggtctgcctg ttctgttggc attagctttt tggctcgtac tgtaccttat tgcgcaagtg
     3121 acgacatcga taggtgggtt attctttaac ttagtggtct taagtttgct ttccgtcatc
     3181 ggactgggtg ttatcaacgg tattacctat agcaagtgga tgccattact gggtaataac
     3241 gcgacttttg gtgtccatca attttccatt aaggtaaacg taaaagaatg cattaaaggt
     3301 tgcatgctcg caatattaac catggttcct ttcatcattg tgattggtat tatgattgcg
     3361 ccagtattcc agcagttaat catgatgagc atgttggggc agtctgaggc aggtggtgag
     3421 cttatattgc aatattaccc acagattatg gcttcctact tcctgtattt tgtcgcgatc
     3481 cttgtgtttg ccagttatct ctatgtcaca ttacgcagtt tgttcctgaa taatctgacg
     3541 ctggcaaatg gaacaattcg ttttcattcg tccgttacca cgttcggtat gctgctgcgt
     3601 atgttggcgg tattaatggg gtcttcaatc acttgtggcc tggcttatcc ctggctgaaa
     3661 atgtggatgg ttagctggat tgccaacaat acccatgttc aaggtgatct tgattcgctg
     3721 gagttaacca atgatgacaa accgcaggat agtggtccgt taatgtggat atctcgcggt
     3781 attatgccgt atgttccgtt tatctaaata aaaaggccgg agcatgctcc ggccttcgtt
     3841 ttcatcactg tgttttgatt acagcgcggc gataacagcc tgctgttcaa tcagcttcgc
     3901 tttcgcttct gcatagcctt ccagcttctc acgctctttc gcgatgaccg cttccggtgc
     3961 gcgggcgaca aagccttcgt tcgccagttt gttctcgata cggctgattt cgccgtcgat
     4021 cttcgccact tctttcgcca gacgcgccag ctcatcttct ttgttgatga ggccagccat
     4081 cgggatcagc agctctgcgc cgtcgatgat cttagtaacg gaaaccggac ctttgtcatc
     4141 ggcaggcagc acggtgatgc tttccagacg cgccagggtt tgcaggaagc cacggttttc
     4201 atttacgcga cgttctgcat ccgcgctgca accacgcagc agcagctcca gcggtttgcc
     4261 cggcgcgatg ttcatttctg cacggatgtt acgtaccgca acgatcgcct gcttcagcca
     4321 ctctgtgtcg gccagtgcgg cttcatcaac ctgagatgca tcgtactgtg ggaacggctg
     4381 cagcatgatg gtgtcggcag tgataccgca aagtactttc acacgctgcc agatggtttc
     4441 ggtgatgaac ggaatgatcg gatgcgcgag gcgcagcaga ccttccagca cggtcaccag
     4501 cgtatggcga gtaccgcgca gttcggcttc ggtgccaccg ttcattaccg gcttggtcag
     4561 ctccagatac cagtcacaga actggttcca ggtgaattca tacagaatgc ctgcagcaat
     4621 atcgaaacgg aagctgtcca gcgcttcgcg gtacgctttg atggtctggt tgaactccgc
     4681 cagaatccag cggtccgcca gcgacagcgt catttcaccg ccgttgaagc cgcaatcctg
     4741 accttctgtg ttcatcagca caaagcggct ggcgttccac agcttgttac agaagttacg
     4801 gtaaccttca agacgcttca tatcccagtt gatgtcacga ccagtagaag ccagcgccgc
     4861 cagggtgaag cgcagggcat cggtaccgtg cggctcaatg ccgttcggga actgtttctc
     4921 ggtgcgctta cggattttgt ccgccagctg cggctgcatc atattgccgg tacgtttttc
     4981 cagcagttct ggcagcgaaa taccgtcaac catatccagc gggtcgataa cgttaccctt
     5041 ggatttggac atcttctggc cttcgtcgtc acgaatcaga ccggtcatgt aaacagtgtg
     5101 gaacggcacc tgcggtttgc cattttcatc tttgatgaag tgcatggtca tcatgatcat
     5161 gcgggcaatc cagaagaaga tgatgtcgaa accagatacc atcacgctgg ttgggtggaa
     5221 ctgacgcagg gcgtcggtgt tttccggcca gccaagggta gagaaggtcc acagtgcaga
     5281 agagaaccag gtgtcgagaa cgtcttcgtc ctgacgcagg gcaacgtcgg caccgaggtt
     5341 attttccttg cgcacttctt cttcgttgcg gccaacataa acgttacctg cttcgtcgta
     5401 ccatgcaggg atacggtgac cccaccacag ctgacgagag atacaccagt cctgaatatc
     5461 gcgcatccag gagaagtaca tgttttcgta ctgcttcggt acgaactgaa tgtcgccgtt
     5521 ctcaaccgct tcaaccgccg gtttcgccag tacatcggca cgcacgtacc actggtcggt
     5581 cagcattggt tcgataacta cgccgccacg gtcgccgtaa ggaacggtca ggtcgtgcgg
     5641 tttaatttct tccagcaggc caagcgcgtc aactgcggca acgactgctt tacgtgcagc
     5701 aaaacgctcc agtttctgga actctgcagg gatttcgctg gaataaacgt cagattcgtt
     5761 acctttggta tcgaacacct gggcgctttc acggatatcg ccgtcaaagg tcaggatgtt
     5821 gatcatcggc agggcgtgac gtttacccac ttcatagtcg ttaaagtcgt gcgccggagt
     5881 gattttcacg cagccggtgc ctttttccat gtcggcgtgt tcgtcgccaa cgatcggaat
     5941 acgacggtta accagcggca gaatgacata tttgccaatc agatctttgt aacgcggatc
     6001 ttccgggtta acggctacgc cagtatcgcc cagcagggtt tctggacggg tagtcgcgac
     6061 caccagataa tctttaccgt ctgcggtttt cgcaccgtca gccagcggat agcggatgtg
     6121 ccacatcgaa cctttcgatt cgcggttttc gacttccagg tcagagatag cggtgcgcag
     6181 tttcggatcc cagtttacca ggcgtttgcc acggtaaatc aggtcttctt tatacagacg
     6241 aacgaaaact tctttcaccg cattggacag gccttcgtcc atggtgaagc gttcacgctc
     6301 ccagtcgacg gagttgccga gacggcgcat ctgacgggta atcgtgccgc cggattccgc
     6361 tttccattcc cagattttgt cgatgaaagc ttcgcggccg tagtcgtgac gggttttacc
     6421 ttcttctgcg gcaatcttgc gctcaacgac catctgggta gcgatcccgg cgtggtcagt
     6481 accgacctgc cacagggtgt ttttgccctg catgcgctga tagcggatca tggtatccat
     6541 gatggtttgc tggaaggcgt gacccatatg caaactgccg gtgacgttcg gcggcgggat
     6601 catgatgcag aaactttcct ggctttcatc gccattaggc ttaaagtagc cctgcttttc
     6661 ccagtgctcg taaagcggct gttcgatatc ttgtgggttg tatgtctttt ccattatttc
     6721 caggttgccg tattcaggtt gaaaccagcc acgcggtagg ctttatagcg ttcgcgcgcc
     6781 agttgtttca gagaatcttc ataaggaacg aagtctacca cttctgtgaa agcggtggca
     6841 aaatctgcaa agcttgttcg cagactaatc aatatatcgc gcgggctgct gctgcgtttt
     6901 tgcggccagg cgatctccac cggcgcaccg ccgcgcggtc cttctcccgc taaattatgc
     6961 ggaacaaagc tttctgccgg acgcgcccac agggcttcat ccagccggta agcctgcttt
     7021 tcatcttcac aggcgatgag cacgcgctta ccgctgcgcc aacgttctgc ggcaatttca
     7081 cacaccagtt gctcaacggc gcttaagcca tcgacggtgg tgtcattgtc cagaaggtag
     7141 aacgtcgcgt ttttcatata tggggcttct tgtggtggat ttaaatacgc atcaggtata
     7201 caccgcagcg cctgatgcga cgctgttgtg tcttatcagg cctacgagtt cagtgctgtg
     7261 tgtaggtcgg ataaggcgct cacgccgcat ccgacaataa cagcattgcc tgatgcgacg
     7321 ctgccgcgtc ttatcaggcc tacgagttcg gtgctgtgta ggtcggataa ggcgttcatg
     7381 ccgcatccga caataacagc attgcctgat gcgacgcttg cgcgtcttat caggcctacg
     7441 agttcagtgc tgtgtaggtc ggataaggcg ttcacgccgc atccggcaat aacagccttg
     7501 cctgacgcaa ttactcttcg ccgttaaacc cagcgcggtt caacaggaac tgtgccagca
     7561 acgctaccgg acgaccggtt gcgccttttg ctttaccaga acgccaggcg gttccggcga
     7621 tatccaggtg cgcccagttg tacttacggg taaagcgcga caggaagcaa cctgcggtaa
     7681 tcgccccacc aggacgaccg ccaatgttcg ccatatcggc aaaattggac tccagttgtt
     7741 cctgatactc gtcacccagc ggtaagcgcc atgcgcggtc accggattgt tcagacgcgg
     7801 caatcagttc atgggccagc ggattgtggt ttgccatcag accagtaatg tgatgaccca
     7861 gcgcgatcac gcaggcaccg gtcagcgtcg ccacgtcaat caccgcttcc ggctcaaaac
     7921 gctcaacgta agttaacacg tcgcacagta ccaggcggcc ttcagcgtcg gtgttgagca
     7981 cttcaacggt ttgaccagac atggtggtta acacatcgcc cggacgatag gcgcgaccgc
     8041 ctggcatgtt ttcacaacct gccagcacgc cgataacatt aatcggcagt tgtagctccg
     8101 cgaccatacg catcacgccg taaaccgccg ccgcgccgca catatcgtac ttcatctcat
     8161 ccatgccttc tgaaggcttg atcgagatac cgccggagtc gaaggttaaa cctttaccca
     8221 ccagcacgat tgggcgtgca tcttccgacg cgttgccttt gtactcaatc accgacatca
     8281 gcgattcgtt ttgcgaaccc tgaccgaccg ccagataaga gtgcatcccc agctctttca
     8341 tctgctgttc gccgataacg cgggtaatga cattcttgct gtagctgtca gccagctggc
     8401 gcgcttgtga agcgaggtaa gcggcgttac agatattcgg cggcatattg ccgagatctt
     8461 ttgctgcttt aatcccggcg gcaatcgcca gaccgtgctg gatcgcgcgc tcaccgctgg
     8521 tcagttcacg gcgggtcggc acgttgaaca ccatcttacg cagcggacga cgcggttcgc
     8581 tcttgttcgt tttcagctga tcgaaactgt agagcgtctc ttttgccgtc tcgacagcct
     8641 gacgcacttt ccagtagttg ttacggcctt taacgtgcag ttcagtcaga aagcagaccg
     8701 cttccattga gccagtatca ttcagcgtat taatggtttt ctgaataacc tgcttgtact
     8761 gacgctcatc cagctcacgt tctttgccgc aaccaataag gagaattcgc tcggaaagta
     8821 cattcggaac atggtgcagc aacaatgtct gccccggttt tccttccagt tcgccccgac
     8881 gtagcagggc gctgatgtac ccatcgctga ttttatcgag ctgttctgca atcggagaaa
     8941 ggcgacgtgg ttcgaagacg cccacgacga tgcaggcact ccgctgtttc tccgggctac
     9001 cgctttttac actaaactcc atgcactacg ctcctgaatc ttaaagacaa cggcggtggc
     9061 tacagataga attgcaagct ttcgtaactc atgtccgctg ttgcgatgac ttcgtgttaa
     9121 tcttaacgtt attacggcat tggcacgtca gaacaaaatc tgagaggtga atccgttgag
     9181 tataattatc ttagcgacga tttcgacgac tcaagagaat aaatgacgtt taagccatga
     9241 aacaagctaa aatcctgcaa aagacgagtt tttacgggcg tatttaaagt gataatcata
     9301 agatatctgg tgcgggagac gctcaaaagc cagctggcga tactcttcat cttgcttttg
     9361 atcttcttct gtcaaaagtt agtgaggatc ctcggcgcag cggttgacgg cgatattccg
     9421 gcgaatctgg tgctctccct tctcgggttg ggcgtgccgg aaatggcgca gcttatcctg
     9481 ccattaagcc tgttcctcgg gctgctgatg acgctgggca aactgtatac cgaaagtgaa
     9541 attacggtaa tgcatgcctg cggcctgagc aaagcggttc tggtgaaagc ggcaatgatc
     9601 cttgcggtat tcacggcaat cgtcgcggcg gttaacgtga tgtgggcggg accgtggtca
     9661 tcgcgtcatc aggatgaagt gttagcagaa gcgaaagcga accctggcat ggcggcgctg
     9721 gcgcaagggc aattccagca agcgactaat ggcagctcgg tgctgttcat cgaaagcgtt
     9781 gacggcagcg atttcaaaga tgtgttcctc gcgcaaattc gaccaaaagg taatgctcgt
     9841 ccttctgtgg tggtggccga ttccggacat ttaacccagc tgcgcgacgg ctcccaggtc
     9901 gtcactctca accagggaac gcgcttcgaa ggcactgcac tgttacgtga tttccgcatt
     9961 acggacttcc aggattatca ggcgatcatt ggtcaccagg cggtggcgct cgacccgaac
    10021 gataccgacc agatggacat gcgtacattg tggaacactg ataccgatcg tgctcgcgca
    10081 gaactgaact ggcgtatcac gttggtattc accgtgttta tgatggcact tatggtcgta
    10141 ccgctgagcg tggttaaccc gcgtcaggga cgcgtactgt cgatgctgcc agccatgctg
    10201 ctgtatctac ttttcttcct gatccagacc tccctgaaat cgaacggcgg taaaggtaag
    10261 ctggacccga cgctgtggat gtggaccgtt aacctgattt atctggcttt ggcgattgtt
    10321 ctcaaccttt gggacaccgt gccggtccgc cgcctgcgcg ccagtttttc gcgtaaagga
    10381 gcggtgtgat gcaacctttt ggcgtacttg accgctatat cggtaaaact attttcacca
    10441 ccatcatgat gacgctgttc atgctggtgt cgctgtcggg cattatcaag tttgtcgatc
    10501 agctgaaaaa agccgggcag gggagttacg acgcgttagg cgcaggaatg tataccttgc
    10561 tgagcgtgcc gaaagatgtg caaatcttct tcccgatggc ggctctgctt ggggcgttgc
    10621 ttggtcttgg gatgctggcg cagcgcagcg aactggtggt gatgcaggct tctggtttta
    10681 cccgtatgca ggtggcgctg tcggtgatga aaaccgccat tccactggtc ttgctgacga
    10741 tggcgattgg cgaatgggtc gcgccgcagg gcgagcagat ggcgcgtaac taccgtgcgc
    10801 aggcgatgta cggcggctcg ttgctctcta cccagcaagg cttatgggcg aaagatggca
    10861 acaacttcgt ctacattgag cgggttaaag gtgacgaaga gttaggtggc atcagtatct
    10921 atgcctttaa cgagaatcgt cgtctgcaat ccgtacgcta tgccgctacc gcgaagtttg
    10981 acccggaaca taaagtctgg cgtctgtcgc aggttgatga atctgatctg accaatccga
    11041 aacagatcac cggttcgcag acggtgagcg gcacctggaa aaccaacctc acgccagaca
    11101 aactgggcgt ggtggcgctg gacccggatg cactctcaat cagcggtttg cacaactacg
    11161 tgaagtatct gaagtcgagc ggtcaggatg ccggacgtta tcagctcaat atgtggagca
    11221 aaatcttcca gccgctatcc gtggcggtga tgatgctgat ggcgctgtcg ttcatctttg
    11281 gcccactgcg tagcgtaccg atgggcgtgc gtgtggtcac cggtatcagc ttcggttttg
    11341 tcttctacgt actggaccag atcttcggcc cgctgacgtt ggtttatggc atcccgccga
    11401 tcatcggcgc actgttgcca agcgccagct tcttcttaat cagcctgtgg ctgttaatga
    11461 gaaaatcgta acctgatgaa cgaataaagg gagcgaaagc tccctttatt attgttagca
    11521 aagtgtgctt cgttcatgcc tgaaaaatca tgaaaatcca atatattgca gtggtgtagg
    11581 catgataaga cgcgccagcg tcgcatcagg caaagacaaa tcgcacctga cttaccttct
    11641 tctccctccc agcaaactcc ccaacattcc acgcacaatc tgattcgtca cctggcgggc
    11701 ggcgcttttc gccattgttt gcacaacacc atctttcttc ccgccgcgtg gtccggtagt
    11761 gccgaacaaa atatccttca atccaccaag aatgccgtca tccaccgcca cctctttccc
    11821 tttcacggca ggattatttt gctgctcggt gcttgcctgt acgccttttt gcaacatctc
    11881 ataggcggat tcccggtcca cgtcatcctc gtacttgcca tacaccggag agtgattaat
    11941 caagccatta cgctcatctt ccgtcaccgg tcccatccgc gaacaaggcg caatcaccat
    12001 cgcccgttcc accacagaag gacttccttt tgcatcgaga aacgagatta acgcctcgcc
    12061 ggtccccagt tcctggattg ccttttcggt atcaaatgcc ggattggccc gcatggtttg
    12121 cgccgcagct tttaccgctt tctgatcttt gggcgtaaaa gcccgcaaag cgtgttgaac
    12181 gcgattaccg agctgcccga gcacattatc cggaatatca gacgggtttt gcgaaacgaa
    12241 ccagacgccc acgccttttg agcgaataag ccttatcact tgctcaatct tatccagcag
    12301 tacctgcggt gcatcgttaa acagcagatg tgcctcgtcg aagaaaaaca ccagttttgg
    12361 tttctccaga tcgcccgctt ccggcaattg ttcatacaac tctgaaagca tccacagcag
    12421 gctggcggcg tacagtttcg gcatctgata aagtttctcg gcgctgagga tattgataac
    12481 gcctttaccg ttggcatcag tacgcatcca gtctttgata tccagcatcg gctcaccaaa
    12541 gaaatgcgtt gccccttgct gttccagcgt cagtaatccg cgctggatgg caccaaccga
    12601 tgcgctacta atattaccgt actgattctg gaatgatttg gcgttatcgc cgatgtactg
    12661 ggtaatcgcc cgcaaatctt taaagtcgag cagtaacagc ccctgatcgt cagcaatgcg
    12721 gaagatgata tttagcacgc cagattgcac atcgttgaga ttcaacagcc gcgccagcaa
    12781 cagcggcccc agatccgaaa ccgtcgcccg caccggatgg cctttctcgc caaagatatc
    12841 ccacaccacc acaggattgg catgcggttg ccagtcattg acgccgatat ttttaagcct
    12901 tgtgagcagt ttttccgacg ccgttcctgc ctgcgcgata ccggtcagat cgcctttcac
    12961 atcagccata aacaccggca cgccgatttc cgacaatgac tctgccagtt tttgcagcgt
    13021 aacggtttta cccgtccccg ttgcgccagt aatcagcccg tgacggttag ccattcccgg
    13081 cagtaaaaac agttctgtgt ccggcgtgcg ggcaattaac aggggttcgc tcatgagatt
    13141 tcctccagtt cctgcctgga gtataggcaa cggctgtgca ctcttcaccg ctaaattcag
    13201 cagattgcga gacgccttcc aaagagattt aagtgccggg cgacagcacc cggcaaaggg
    13261 atcagaagtc ggctttcagg actactcggt agcgagcttt accatcgcgt acatgctgaa
    13321 tggcgtcgtt aattttcgac atcgggaaca gttcggttgt cggcgcaacc ttgctgcggg
    13381 cggcaaagcg catcagcttt cgcagctcat aaggcgtgcc ggtagcagaa ccagagatgc
    13441 tgcggtcgcc cgcaattaac gtaaaggccg gaacagacag cggcgtgaga accgcaccga
    13501 ccgtatggaa attaccgcca taggtcagcg cctcaaaata aggctgccag tcgaggctga
    13561 cgttcacagt attgataatg agatcaaact gccccgacag ggctttcagt gcctgcggat
    13621 cgcggctatt caccacttta tcggcaccca tcgccagtac ttcctgctct ttcgccggat
    13681 tagaactaaa ggccgtcacc tcgcatccca ttgcgtgcag aagttttata gcgatatgcc
    13741 ccagcccgcc aataccaatt accccaacgc ggctggtagc agtgatatgg tgcatcaaca
    13801 gtggtttaaa gaccgtgata ccgccgcaca acagcggccc ggcggactcg atatcaatat
    13861 tttctggcag tggaatcacc cattgccagt ccgcacgcaa cttctcggca aagccaccgc
    13921 gattcataat cgtcggcacc gcaccttgct cgcagttgat ctgattaccg ctaatacagg
    13981 cgtcgcagtg accacagcta cgcgccgtcc agccaatccc gacacgctga ccgacctgca
    14041 aacctttatc ctgcgcggcg ctcccgagtg ccaccacgcg cccaatcacc tcatgcccgg
    14101 caaccagcgg atattgtgaa aatccccatt cgttatcgat catcgacaga tcggaatgac
    14161 aaatcccgca gtaatccacc tgcacttcaa catcttgtgg cttcagctca ccgggatcgt
    14221 actcataaac ttccagttcg ccgcccgctt cttttgcggc atagcttttt atcatcgaca
    14281 tttttgggtc cttctctggt gttgtttggg aagtgtagag catggcaggg cggggtgcct
    14341 ggagtgtgac aaaggttaca tatcgctgag tgtaatgctg aaaatttcag cacttagcga
    14401 ggtgggtgca agctggcgct tgcatggtgg cgtgcgacag gtataatcca caacgttttc
    14461 cgcatacctc ttcagtgccg aagtggcgaa atcggtagac gcagttgatt caaaatcaac
    14521 cgtagaaata cgtgccggtt cgagtccggc cttcggcacc attaacactt cttttgacgt
    14581 ttcctgaagt ctctaaatac aaaaaaatcc ttaaaaaaca agcaaagtat ggtatctaat
    14641 ggtctttgtt ggtctcttgt agtctacctt cttttggggg cataatcggg ggcatgtcaa
    14701 ttcgatgagg atttgtgccc ccaaaatgaa actcaacgct cgccagatag agaccgcaaa
    14761 gccgaaagag aaagcttata aaatggctga tggaggcggt ttgtatcttg aggtctcccc
    14821 taaaggttct aagtactggc gcatgaaata tcgccgcccc tctgacaaaa aggaagatcg
    14881 actcgctttt ggtgtatacc cgacggtcac tttggctgaa gcgcggggta agcgcgatgc
    14941 agcaaagaaa ttgttgtctc agggtattga ccccaaagct gagcaaaagg gggcacaagc
    15001 tgaaattgag ggggcatatt tatttgaaac tatcgcaagg caatggcacg caagtaacct
    15061 tacttggagc gaagatcata gccgtcgtgt tctgctgaca cttgagcagt atattttccc
    15121 ctcgataggt caaatcgatg ccagaacgtt gagaaccagc cagcttctca atccaatcaa
    15181 agctgtcgat acggcgggta aacatgatgt cgcgcagcga ctgatgcagc gcgtaaccgc
    15241 aattatgcgt tttggtgtgc agaatgacct ccttgaatca aatcctgcat gcgatatggc
    15301 tggagcgctt ttaagcgtta aagcaaccca ccacccagca ctacccccaa aaagaatccc
    15361 tgagcttctt gaaagactat cacgctataa agggcgacta atgacacggc ttgccgttga
    15421 attaacgcta ctcacattta tacgttcaag tgagatgcgt tttgctcgct ggagtgaggt
    15481 taactttgaa cgaagcgagt ggacaatacc cggaattcgt aagcctattc ccggcgtaaa
    15541 acactctgag cgtgggatga agatgaaaac tgaacatatt gttccgctta gcaaacaagc
    15601 atttgatatt tttaaacgtt tacatgcctt gagtggtaaa ggtgaggtta tatttcccag
    15661 cgatcatgat cctaaaaaag taatgagtga aaatacagta aataacgcct tacgtgtaat
    15721 gggatatgat acgaaaactg aagtatgtgg tcatgggttt agaactatgg cgcgtggtgc
    15781 gctaagtgag tcgaaactat ggaatgatga tgccattgaa agacagttaa gccacgttga
    15841 acgaaaaaat gtgaaaggtt catatatgca tacttccgaa tatcttgaag aaagaagatt
    15901 aatgctgcag tggtgggctg attatattga tgctaataag aatggatctg tcacaccata
    15961 tgattttgcg cgtatgcatg gaaaataatt accattgggg gctgcggaga gatttaaatg
    16021 aataatactc aatttgataa taatttgttt tattttaata ggttaactta cataacgcca
    16081 cacgaagtgg cgcttgctat gaatggtttt gactatgata ccgaaaatga tgaattgact
    16141 gaggttcaat taaaagaggt tattagatta agaaaggcaa taaccagaaa tctacaatta
    16201 attaatgaat ataaaaacgt atccgccacg caaaaagtgg aggcgaactt attattaact
    16261 gccgcttata tctttcagag ggaaggtatt gtacctgtgg agattaagga gagaattgag
    16321 aacgcattac gacaacaggt aaaaaataaa gattggagtg atattctaat gacgttagga
    16381 ggaagtgaat tatatgaagt tggtaaaaaa ttaaggagta atggtagagg gcagtacaga
    16441 aaagatgatg aggataatta tagttgtaaa ttaatttatt tactaattga attgcttaa
//
LOCUS       DACAOP010000098        16228 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.098, whole genome shotgun sequence.
ACCESSION   DACAOP010000098 DACAOP010000000
VERSION     DACAOP010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16228
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.098"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..916)
                     /locus_tag="IT892_003562"
     CDS             complement(<1..916)
                     /locus_tag="IT892_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002437660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="HAP3136739.1"
                     /translation="MNSTKMPVIENIELMTARVPLPEGPWGDQIHHVTDIEVAIVDVY
                     GSNGQIGTGFSHTSGWCGKTISALIAEIIPDVIGQPLSPRGLWHRSYKYIHDVGGAGV
                     TTHALAALDIAYWDLLGKTLNAPIVDIIGKVRDRVPLYGSGINLHLSIEEVIDQVKRW
                     KSIGYQAAKVKVGKPTLEEDVERLRKIQEAVQGFPLAVDANQGWNFPQALRAFKLFEP
                     LNLLWIEEPLPSDDITGHMKLRERSTTPIALGENVYNLNQFTQYIESGCADYVQADLG
                     RVGGITGYLDIAAVARAHNLPMTPHFVME"
     gene            complement(974..2428)
                     /locus_tag="IT892_003563"
     CDS             complement(974..2428)
                     /locus_tag="IT892_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136740.1"
                     /translation="MYQQQHLEFIIQKAKKRLDSQEAPGCTKAGWLMITALLIESWDI
                     YSMAFILFALKDIYEPSAWLLGFTAAGTQLGAVIGALLGGWLTDKLGRRKIFLWSMIL
                     FAIFALLQGLAPDMYWLAIIRCLAGIPVGADVANGFTYIMEVMPKGKREVMANRWQFM
                     FALGIIVAILLVTGLVALDVHPDMIWRIVLAVPAIPACMLLFMRRELPETPAWFVERG
                     RFIEAKQASREYYGEQDGKLLDDILPNENVQIPHPTLKETLHDLFRRPFTRRTTLFGW
                     FSCAVQSFENYAFSFYLPLILVTIGISGQIQNNLALLVVNCIAALSAFVGPLLLPKLG
                     HKGLSKWGFLLVAIGISISSWGVYSSSFGFITFGAALMLWGHYWDSESGMTVISLVAK
                     PRYRGVVSGIGYTIVKVTAFITTLVFPPLFEKLGVPLASLIIAIAPFCAFLASIFLLP
                     EVFGHAVGDEHDQPYTENSDAALPGQQSSVSPKN"
     gene            complement(2571..4226)
                     /locus_tag="IT892_003564"
     CDS             complement(2571..4226)
                     /locus_tag="IT892_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein"
                     /protein_id="HAP3136741.1"
                     /translation="MPMLNLTLPVEDAPLTPQPGEVLMVTNADLREPANVTCWPTQKS
                     FEQRLEAALEKLGYRMRRAHPVNESRGHGFISSQKEGSDLFATLDPDAPVIVLLTAWQ
                     YSHHIAPSLVHHRGPILLLANFDGTWPGLVGMLCMAGCLTSLERNYSRLWSETFEDDA
                     FMRGLDTWLRDGHLSHKLSYLHPVPASAPLLASETGQIGVKVGQSILKHKAIVGLFDT
                     FCMGMINGVFPQKAMIDVGIPVESLSQSALLVEMNKVPQALREACLDWYETRGMRFNF
                     GTHSAEELTREQVLEQCAMMIAMARFVKRFGLSAIGVQYQQGLKDSCAASDFAEGAIG
                     NSERFPIPDEQGEIICPDAPIPCINEVDMGSAIPQVMMAKLLGALGLESETTLHDIRW
                     GSEYNGTFYWDLEISGAVPFAHLKGGIAGATGYRQPPMFFPYGGSTITGQGKAGRFIW
                     ARAHYEGTQVIMHIGTGTAVELPEAEFERRRKATNYEWPLLNAVLDGVTRDDLMAGHQ
                     SNHLSLAYVDEALLAGVLTAFVAQALTQNIRVYLAGEAHSLVQ"
     gene            complement(4244..5851)
                     /locus_tag="IT892_003565"
     CDS             complement(4244..5851)
                     /locus_tag="IT892_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAP3136742.1"
                     /translation="MNAEAYIGVDVGSGSVRAGIFTAAGQRLAFTVKPVSQFHDAGDC
                     IEQSSTEIWQAVCAAVSESVQAAGIDPAQIRGIGFDATCSLVAVRADGTGISVSPAGQ
                     PERDIIMWRDHRAQEETREINATGDDALRYVGGEVSVEMQLPKILWLKRHLPDRYAQI
                     WRLFDLADYLVWRACGNEVASTCTLTCKWNYLAHEQRFSQSLLRSIGLEEVVGKIPAT
                     VRDPGEKAGTLRPELARVWGLPEDVAVATGIIDAHAGGLSLSGARPQGSLAIISGTSN
                     CHMIVSQQPVLIPGVWGPYWGAMLPQLWLNEGGQSAAGALVEWTLRQHASWATLQQES
                     DSTGVSPYQLLNQQVEQLEAVERWPTRHLHVLDDHHGNRSPRANPLARGAVYGLTLEE
                     GVSGLARLYLATLQAIAYGTRHIIEAMRAAGHDVSRIMMCGGATKNPLWLREYANATG
                     CDIHLAREEDAVTLGAALLGSVACGGFASLTDAVAAMSRHGHTITADRSPSTQAFHRA
                     KYQVYLQMYDDLQRAEARFNTTMNTTQ"
     gene            6336..6652
                     /locus_tag="IT892_003566"
                     /pseudo
     CDS             6336..6652
                     /locus_tag="IT892_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016809989.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
     gene            6693..6983
                     /locus_tag="IT892_003567"
     CDS             6693..6983
                     /locus_tag="IT892_003567"
                     /inference="COORDINATES: protein motif:HMM:NF019984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136743.1"
                     /translation="MHAQTTRRWNSTPIAQRVERLNPLLREWASYFNQGPVSQIYRDI
                     DNYTARRGRIWLRRRKGQWGTGYRQYSDQYVYTLLGLIHLLDISRNRPNAKV"
     gene            6999..7385
                     /locus_tag="IT892_003568"
                     /pseudo
     CDS             6999..7385
                     /locus_tag="IT892_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008786676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            7399..7656
                     /locus_tag="IT892_003569"
                     /pseudo
     CDS             7399..7656
                     /locus_tag="IT892_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            7708..8385
                     /locus_tag="IT892_003570"
     CDS             7708..8385
                     /locus_tag="IT892_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HAP3136744.1"
                     /translation="MSIIFNGHYRMEYRTWITEALRLHFEEHLPRIVAGRRLGVPKST
                     VCGMFVRFRKAGLSWPLSAGMSERELDARLYGSASTVPVVLTENTVMSEVPVVKKRPR
                     RPNFPYEFKIALVEQSLQPGACVAQIARENGINDNLLFNWRHQYRKGGLLPSGKNMPA
                     LLPVTLTPEPDNKIPAPAQEPEQINTPSDSLCCELVLPAGTLRLKGELTPALLQTLIR
                     EMKGSSH"
     gene            8385..8732
                     /gene="tnpB"
                     /locus_tag="IT892_003571"
     CDS             8385..8732
                     /gene="tnpB"
                     /locus_tag="IT892_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAP3136745.1"
                     /translation="MISLPAGSRIWLVAGITDMRNGFNGLASKVQNVLKDDPFSGHLF
                     IFRGRRGDQIKVLWADSDGLCLFTKRLERGRFVWPVTRDGKVHLTPAQLSMLLEGINW
                     KHPKRTERSGIRI"
     gene            8752..10030
                     /locus_tag="IT892_003572"
                     /pseudo
     CDS             8752..10030
                     /locus_tag="IT892_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(10020..10148)
                     /locus_tag="IT892_003573"
                     /pseudo
     CDS             complement(10020..10148)
                     /locus_tag="IT892_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418698.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(10271..10942)
                     /locus_tag="IT892_003574"
     CDS             complement(10271..10942)
                     /locus_tag="IT892_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000906845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAP3136746.1"
                     /translation="MLIPEIKQERLYQKIANLIIKLINDNVFPPGSFLPPERELAKQL
                     GVSRSSLREALIVLEISGWIIIQSGNGIIVSDNKHSPVDYTIEEILYVRDLVDSHCAR
                     LAALANNETIINKIELLHFRMENSIHENNVAEFYMLDKQFHLTISEASHNRVLLDMSR
                     MLWEQRVNIPYAGLDKRSGDKNVLIKLNQQHKAIIEAIRAGNADNALQRALLHLKYVR
                     EIIGY"
     gene            complement(10990..11349)
                     /locus_tag="IT892_003575"
     CDS             complement(10990..11349)
                     /locus_tag="IT892_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001361993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136747.1"
                     /translation="MICEHILISAYVFLYGAEGFIILFVETELSHAKIILENLRNKMA
                     GLRIQALVSERFSVTDNIGVDEYDFYPDYNLLIEREGVLLRQKSGSKPDRRLSATDDK
                     LLIFRHCHAKPVDPNQV"
     gene            11671..11955
                     /locus_tag="IT892_003576"
                     /pseudo
     CDS             11671..11955
                     /locus_tag="IT892_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447023.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            12110..12397
                     /locus_tag="IT892_003577"
     CDS             12110..12397
                     /locus_tag="IT892_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HAP3136748.1"
                     /translation="MTPAQRRQHYDAWRVSGMSRTAYARQHGINNKTFWHHCRAFSAD
                     DARGPAPADNRPAILPVTLSVSDTATLKLQCACVTASPAGIAAIIRELNLC"
     gene            12391..12729
                     /gene="tnpB"
                     /locus_tag="IT892_003578"
     CDS             12391..12729
                     /gene="tnpB"
                     /locus_tag="IT892_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAP3136749.1"
                     /translation="MLSPHSLWLVREPADIRAGIDSLTRLATQAAGHPPREGEAFLFT
                     GKKRTRMKLLMWDRHGVWLCTRRLHQGAFRWPRDGDTTWSLTAEQFAWLTAGVDWLRL
                     SASPLQRWTE"
     gene            12804..14468
                     /locus_tag="IT892_003579"
                     /pseudo
     CDS             12804..14468
                     /locus_tag="IT892_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612177.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(14632..14760)
                     /locus_tag="IT892_003580"
                     /pseudo
     CDS             complement(14632..14760)
                     /locus_tag="IT892_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459923.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(14768..15435)
                     /locus_tag="IT892_003581"
                     /pseudo
     CDS             complement(14768..15435)
                     /locus_tag="IT892_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_025243830.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15578..16040)
                     /locus_tag="IT892_003582"
                     /pseudo
     CDS             complement(15578..16040)
                     /locus_tag="IT892_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446915.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3738 a         4493 c         4401 g         3596 t
ORIGIN      
        1 gctccatgac aaagtgcggg gtcatcggca ggttatgagc gcgtgcgacg gcggcgatat
       61 cgagatagcc ggtaatacca cccacgcgtc ccagatccgc ttgcacataa tctgcacagc
      121 cactctcaat atattgcgtg aactggttta agttatagac gttttcaccc agggcgatcg
      181 gcgttgtact gcgttcgcgc agtttcatgt ggccggtgat gtcgtcggaa ggcagcggtt
      241 cttcaatcca cagcaggtta agcggttcga acagcttgaa cgcgcgcagt gcctgcggga
      301 agttccagcc ttggttggcg tccaccgcca gcgggaagcc ttgcaccgcc tcctgaatct
      361 tacgcagccg ctccacgtcc tcttccagcg tcggtttgcc cactttcact ttcgccgcct
      421 gatagccgat gcttttccag cgcttgacct ggtcgatcac ttcctcaatg gacagatgca
      481 ggttgatgcc gctgccgtac agcggaacgc ggtcgcgcac tttaccgatg atgtcgacaa
      541 tcggcgcgtt gagggttttg ccgagcaggt cccagtacgc gatatccagt gcggcgagcg
      601 catgtgtcgt cacgcccgcg ccgccgacgt cgtggatata tttatacgag cggtgccaca
      661 gcccgcgcgg cgacagcggc tgcccgataa cgtccggaat aatttcagca atcagcgccg
      721 agatggtttt cccgcaccag ccggaagtat ggctaaaccc ggtcccgatt tggccgttag
      781 agccgtacac atcgacaatc gccacttcaa tatcggtaac gtggtggatc tggtcgcccc
      841 acgggccttc cggcaacgga acgcgggcgg tcatcagttc aatattttca ataacgggca
      901 ttttggtgct gttcattatg atcatccttc tttcatgacc gtggccgctc tagcggcgca
      961 cggtcgggga acattagttt ttgggagaaa cagaagattg ctgacccggt agcgcggcgt
     1021 cggagttctc cgtatacggc tgatcgtgct catcgcccac ggcatgaccg aacacttccg
     1081 gcagcaggaa aatcgacgct aggaaggcac agaacggcgc gatagcaatg atcagcgacg
     1141 ccagcggtac tccgagcttt tcaaacagcg gcgggaacac cagcgtggta atgaatgcgg
     1201 tgactttcac gatggtgtaa ccgataccgg aaaccacacc gcgataacgc ggtttcgcta
     1261 ccagcgaaat gacagtcatc ccgctttcag aatcccagta gtggccccac agcatcagcg
     1321 ccgcgccgaa ggtgataaac ccgaaactgc tggagtagac gccccacgac gaaatggata
     1381 tccctatggc caccagcagg aaaccccatt tactcaatcc cttgtgcccc agcttcggta
     1441 acagcagcgg gccgacgaaa gccgacagcg cggcgataca gttcaccacc agcagagcga
     1501 ggttgttctg gatctggcct gagataccga tggtgacgag gatcagcggc agatagaatg
     1561 aaaatgcata gttttcaaac gactgcaccg cgcaggagaa ccagccgaac agggtcgtgc
     1621 ggcgggtgaa cggacggcgg aataggtcgt gcagcgtctc tttaagcgtc gggtgaggga
     1681 tctggacatt ctcgttgggc agaatatcgt ccagcagctt gccgtcctgc tcgccgtagt
     1741 attcgcggga cgcctgttta gcctcaataa agcgaccacg ctccacaaac cacgccgggg
     1801 tttccggcaa ttcacggcgc ataaacaaca gcatacatgc cggaatcgcc gggactgcca
     1861 gaacgatccg ccagatcatg tctgggtgaa cgtcaagcgc cactaggccg gtgaccagca
     1921 gaatcgcgac gataatcccc agcgcgaaca taaactgcca gcggttagcc atgacctcgc
     1981 gcttgccttt cggcatcact tccatgatgt aagtaaagcc gttcgcgacg tcggcaccca
     2041 ctgggatccc ggcgaggcag cggataatcg ccagccagta catatccggt gccagcccct
     2101 gcaggagtgc gaaaatggca aacaggatca tcgaccacag gaaaattttg cggcgaccga
     2161 gtttgtcggt cagccagccg ccgagcaggg cgccgatcac cgcgcccagt tgcgtacccg
     2221 cggcggtaaa accgagcagc caggcactcg gctcataaat gtctttcagg gcgaacagaa
     2281 taaaggccat ggaatagata tcccatgact caataagtaa ggcggtaatc atcagccagc
     2341 ctgctttggt gcagcccggc gcttcctggg aatcgaggcg tttttttgcc ttctggataa
     2401 taaattcaag gtgttgctgc tgatacataa aatcctccct tacccggacg ggcacggtgc
     2461 ccgcccgaac agaaacatat tgacccgctc cttcaagata caaggagtca gattaaccga
     2521 atgtttgtca ggatcgctaa cagcgtaaaa attacataag cgagtgagtg ttattgcacg
     2581 agcgaatggg cctctcctgc gagataaact cggatgttct gcgtcagcgc ctgggcgaca
     2641 aaggctgtaa gtacgccagc cagcagcgcc tcatcgacgt aggccagact caggtgatta
     2701 ctctggtgcc ctgccatcag gtcatcgcgg gtgactccat cgagcacagc gttcaacagc
     2761 ggccattcat agttggtggc tttgcggcga cgttcgaact ctgcttccgg cagctcgacg
     2821 gcggtaccgg tgccgatatg cataatgacc tgagtgccct cataatgggc gcgcgcccag
     2881 ataaagcgtc cggccttgcc ttggcctgtg atagtagaac cgccgtacgg gaagaacatc
     2941 ggcggctgac ggtagccggt ggcaccggca atgccgcctt tgagatgggc gaacgggacc
     3001 gcgccggaga tttccagatc ccagtaaaac gtgccgttgt actcgctgcc ccagcggata
     3061 tcgtgcagcg tggtttcgga ctcaaggccc agcgccccca gcagtttcgc catcatcacc
     3121 tgcggaatag cactgcccat gtccacttcg ttaatgcacg ggatcggcgc atccgggcag
     3181 ataatctcgc cctgttcatc cgggataggg aagcgctcgc tgtttccaat cgcgccttcg
     3241 gcgaaatcgg acgcagcgca gctgtctttc agcccctgtt gatactggac gcctatcgcc
     3301 gacagtccga agcgcttcac gaagcgcgcc atggcaatca tcattgcgca ttgctccagc
     3361 acctgctcgc gggtcagttc ttcggcgctg tgggtgccga agttgaagcg catcccacgg
     3421 gtttcatacc aatccaggca ggcttcgcgc agcgcctgcg gcaccttgtt catctcgacc
     3481 agcagcgccg actgcgacaa cgactccacc gggatgccga cgtcaatcat cgctttttgc
     3541 gggaagacgc cgttgatcat ccccatacag aaggtgtcga acaggccgac gattgcttta
     3601 tgtttgagga tcgattgacc gaccttcacg ccgatttgcc cggtttcgct tgccaacagc
     3661 ggcgcgctcg cgggcaccgg atgcagatag ctgagtttgt ggctaagatg accgtcgcgc
     3721 agccaagtat cgagcccgcg cataaacgcg tcgtcttcaa aggtttccga ccacaggcgg
     3781 gagtagttgc gctcaaggct ggtcaggcag cccgccatgc acaacatccc caccaagccc
     3841 ggccaggtgc cgtcgaagtt ggcgagcagc aggatcggcc cgcgatggtg caccagcgac
     3901 ggagcgatat ggtgggagta ttgccacgcg gtcaacagca cgatcacagg ggcgtccggg
     3961 tcgagggttg cgaacagatc gctgccttct ttctggctac tgataaagcc gtgaccgcgg
     4021 ctttcattca ccggatgggc gcgtcgcatg cgatagccca gtttttccag cgctgcttcc
     4081 aggcgctgtt caaatgattt ttgcgtcggc cagcaggtga cgttcgccgg ttcgcgtaaa
     4141 tccgcgttgg tcaccatcag cacttcgcca ggctgtggcg tgaggggggc atcttccacg
     4201 ggcagggtta aattcaacat cggcatagct cctccaaggg cgatcattgt gtagtgttca
     4261 tagtggtgtt gaaccgcgct tccgcccgtt gcaggtcgtc gtacatttgc agatagacct
     4321 ggtatttagc ccgatggaag gcctgggttg atggagagcg atcggcagtg atggtgtggc
     4381 cgtggcggct catggcagcg acggcatcgg tcagcgacgc gaaaccaccg caggctacgc
     4441 tgccaagcag cgcggcgccg agggtgacgg catcttcttc ccgggcaaga tgaatatcgc
     4501 agccggtggc attagcgtat tcccgcagcc acagcggatt tttggtcgcc cctccgcaca
     4561 tcatgatccg cgacacgtcg tgcccggcgg cgcgcatggc ctcgatgatg tggcgagtgc
     4621 cgtatgcaat ggcctgtagc gtggcgagat agagccgcgc caggccgctg acgccctctt
     4681 caagggtgag tccgtacacc gcaccgcgtg ccagcgggtt ggcgcgggga gagcggttgc
     4741 cgtggtggtc gtcaagcaca tgcaggtggc gcgtcggcca gcgttccacc gcctccagct
     4801 gttccacctg ctgattcaat aattgatagg gcgacacacc cgtggagtcc gactcctgct
     4861 ggagcgtggc ccaggacgca tgctggcgca gcgtccattc caccagcgcg cccgccgcgc
     4921 tctgaccgcc ttcattcagc cacaactgcg gcagcatcgc accccagtaa ggaccccaga
     4981 cgcccgggat cagcacgggt tgttggctga cgatcatatg gcagttggag gtgccgctga
     5041 taatagcgag actgccctgc ggccgggcgc cgctcaacga taatccgcct gcatgggcat
     5101 caatgatacc ggtcgccacc gccacgtcct caggcaatcc ccatacgcgg gcgagttccg
     5161 ggcgcaacgt tccggctttt tcaccgggat cgcgcaccgt ggcggggatt tttcccacca
     5221 cctcttccag cccgatagat cgcagcagcg actggctaaa acgctgttcg tgggccaggt
     5281 agttccattt acaagtcaag gtgcaggtac tggcgacctc gttgccgcag gcgcgccaca
     5341 ctagataatc cgccagatcg aacaaccgcc agatctgcgc gtagcgatcc ggcaaatggc
     5401 gcttaagcca aaggatcttc ggtagctgca tttccacgct gacttcaccg ccaacgtagc
     5461 gtaatgcgtc gtctcccgtg gcgttgattt cacgtgtttc ttcctgtgcg cggtgatcgc
     5521 gccacatgat gatgtcacgc tccggctgac cggcagggga gacggaaata ccggtgccat
     5581 cggcgcgaac ggccaccagc gagcaggtgg catcgaagcc gatccctcgg atctgcgccg
     5641 ggtcgatccc cgccgcttgg acgctttcgc ttaccgcagc gcagaccgcc tgccagatct
     5701 ctgtcgatga ctgctcaatg caatcaccgg catcatgaaa ctggctgaca ggtttaacgg
     5761 taaaggccag ccgctgaccc gccgcggtaa agatcccggc ccggacgcta ccggaaccaa
     5821 cgtctacgcc aatgtaagcc tctgcgttca ttgctacccc cccccctaag ctaactcgaa
     5881 ttagcaagtt atgataaaaa aaacgcctgc tcaaattttt tgccatggtt ttgtgatggt
     5941 cttcaaagtc ttttttttat ctggctgaaa aataataatt attttaagtg cggcgaaccg
     6001 ggctgccttc taagacgttt ctttggaaaa aatgatttat aaaggcctcc caacagtgga
     6061 gagcggatat attttggaaa gggcgaagac gtagagagat aattggctga aattacactc
     6121 ttttaaaata caaaatgtag gtgttttctg ctggtcaccc ggcgagttga gtaaaaatta
     6181 aaccgatccc gctcacactc ttcattcatt ctagttgtga atattttgta attgccataa
     6241 ttagctaatt cgagttagct gcgagcaact ttccccgctc tgccagcgtg gtgcaaacca
     6301 acaacacaat aacgattcgg acagaggatt gaatgatgac agtgattacc tcgcctacac
     6361 tgcctgccac gaaagataac acgctttcgc agcccgccca ggaaagaaaa aaactgatta
     6421 ccgtgctggg cttcggtcta tcaggcacca ccattgagtt ctacgatttc tttatttacg
     6481 gcacggcggc ggcgagtggt gtggggcgac gacgttgata accgaatacg cgccgcgcaa
     6541 ccgtcgcggg ttcttcggca cctttgtgta actgggtaac gtgctggaat tgtttatcgc
     6601 caccgctgtg tttgcgctgg tggttatgct gctcgaagac gatttgatgt cctagggctg
     6661 gcgtgtgccg ttcctaacga cttaagcagg aaatacacgc ccagactaca cgacgctgga
     6721 atagtactcc catagctcaa agagtggaaa gattaaatcc gcttctcagg gaatgggcca
     6781 gttacttcaa tcagggacca gtgtcacaga tttaccgcga cattgataac tacacggcga
     6841 gacggggcag gatctggtta cggagaagga aaggtcagtg gggaacgggg tatcgtcagt
     6901 attccgacca atacgtgtat acgctgttag gattgataca cctgcttgat atttcccgta
     6961 accgcccgaa cgcgaaggtc tgatgtgctg caagagggcc ggatgcgagc cattttacct
     7021 catggctatg tttgtccccg ggaaataaga tctccggtgg aaaagtgttg tccgcgaaaa
     7081 cgagacgttc atccagtcga atcgctgctg cacccaggct ggcagtcaca acgattggtc
     7141 ggagcaatac tgcgttgagt gctttttatc gtcgattatc atcccgtatt gggaaagcaa
     7201 aagcagtcac tgtaacggca agaaaactgg caatactgtt ctacaatgcc ttgaaatatg
     7261 gtcaaaaata tgtcgaccat tgtgctgatt attatgaaga gcgttaccgt agtcacgtac
     7321 tcaatggact taaacaaaga gcaacatcac tgggttattc tctccagcaa gaccctgaat
     7381 tatgagtgtg aaccaggagt ttctcaggaa gtctaccgcg ctcttgatgt cagattcctg
     7441 aacagtctcg ataatcggaa aactcagagc acattatcct gtgttcacac tctgccatgt
     7501 gttcggggtt catcgctgca gctacagata ttggaaaacc cgtcctgaaa aaacagacgg
     7561 cagatgggct atgtaattga gctgcatggc agagccaaga gcattgctac aatggcaacc
     7621 cggagagact accagatggg acgctggctt gctggtaagc gcctcatctg aaccgtctgg
     7681 tctgtttcct ccggctccac aaaaataatg tccatcattt ttaatggaca ctatcgtatg
     7741 gaataccgga cctggatcac cgaagcttta cgtcttcact ttgaagaaca tttaccacgg
     7801 attgtggccg gacgtcgcct gggcgtacca aaatcaacag tttgtggtat gttcgtgcgc
     7861 ttccgcaaag ctggcctttc atggcctctg tccgcaggta tgtcggagcg ggaacttgat
     7921 gcccgtcttt acgggagtgc ctccacagta cctgtcgtac ttactgaaaa caccgttatg
     7981 tccgaagtcc cggtggtaaa aaaacgtccc cggcggccta attttcctta tgagtttaaa
     8041 atcgccttag tagagcagtc actgcagccc ggagcctgtg tggcgcagat cgcccgtgaa
     8101 aacggaatca acgataacct gctcttcaac tggcgccatc aataccggaa aggtggcctg
     8161 ctgccttccg gaaaaaatat gcctgcactg cttcccgtga cgttaacgcc ggagccggat
     8221 aataaaatcc cggctccggc acaggaacca gagcagataa atacaccgtc cgacagtctg
     8281 tgctgtgagc tggttctgcc agctggaact ctcaggctga aaggtgaact gacaccggcg
     8341 ttattacaga cacttatccg cgaaatgaaa gggagcagcc actgatgata tctctccctg
     8401 ccggttcgcg tatctggctg gttgccggca tcaccgacat gcgaaatggc tttaacggcc
     8461 tggcctcaaa agttcagaac gttctgaagg atgacccgtt ctccgggcat ctgttcatct
     8521 tccgcggacg ccggggtgac cagataaaag tgctgtgggc tgacagtgac ggactgtgcc
     8581 tcttcaccaa acgcctggag cggggccgct tcgtctggcc ggtcacccgc gatggaaagg
     8641 ttcaccttac tccggctcag ttgtccatgc ttcttgaggg catcaactgg aagcacccga
     8701 aacgaacgga acgctctgga atccgcatat aacccgttgt aaagtgagga tatggacacc
     8761 tcacttgctc atgagaatac ccgcctgcgg gcactgttgc agacgcaaca ggacaccatc
     8821 caccagatgg ctgaatacaa ccgcctgctc tcacaacggg tggcggctta tgcttccgaa
     8881 atcaaccggc tgaaggcgct ggttgcgata ctgcagcgca tgcagctcgg taaaagctca
     8941 gaaaaacttc gcgcaaaaac cgaacggcag atacaggaag cacaggagcg aatcagcgca
     9001 cttcaggaag aaatggcgga aacgctgggt gagcagtatg atccggtact gccatccgcc
     9061 ctgcgccagt cttcagcccg taaaccgtta ccggcctcac ttccccgtca aacccgggtt
     9121 atccggccgg aagaggaatg ctgtcctgtc tgtggtggcg aactcagttc tctgggatgt
     9181 gatgtgtcag agcaactgga gcttatcagc agcaccttta aggttatcga aacacaacgt
     9241 ccgaaactgg cctgttgccg gtgcgaccat atcgtgcagg ctccggtgcc ttcaaaaccc
     9301 attgtacgca gttatgccgg accggggctt ctggtccatg ttatcaccgg gaagtatgcg
     9361 gaccatctgg cattataccg tcaatcagaa atataccgtc gtcagggtgt ggacctgagt
     9421 cgtgccacgc tgggtcgctg gaccggtgct gttgctgagc tgctggagcc gctgtatgac
     9481 atcctgcgcc agtatgtgct gatgcccggt aaagtccatg ccgataatat tcccgttccg
     9541 gtccaggagc cgggcagcgg taaaacaagg attgcccgac tgtgggtcta cgtccgtgat
     9601 gaccgtaacg cagattcgga aatgcctacg gcggtctggt tcgcgtacag cccggaccgg
     9661 aaaggcatct atccacagaa ttatcttgct ggttacagcg gagtgcttca ggccgatgct
     9721 tacggtggtt accgggcgtt atacgaatcc ggcagaataa cggaagccgc gtgtatggct
     9781 catgcccgga gaaaaatcca cgatgtgcat gcaagagtgc ccaccgatat cacccctgca
     9841 gcgtatcggt gaactgtatg ccatcgaggc agaagtccgg ggatgtacag cagaacagag
     9901 tctggcggca agaaaagcca gagctgcgcc actgatgcag tcactgtatg actggataca
     9961 gactcagatg aaaacactgt cgcgtcactc ggatacggca aaagcgttcg catacctgct
    10021 gttacagtac ctgattcggc aaggcaacga gagatgagtt cggggtcgag gtaatccccc
    10081 agagaagtca gtgggttacg cagagaatcg taacgggata ccagatcaag ggcctgtccc
    10141 atgtgcataa aaaatccgga aacgagtgag cgtttccgga ttcttacaca gccactggat
    10201 cggtcaactg atccttaact gatcggcatt acggctatac cggaggtata tttattcagc
    10261 gcagaaaagg ttaataacca attatttctc gcacatactt caaatgtagc agtgcccgtt
    10321 gcaaggcatt gtctgcattt cctgcacgaa tcgcctcaat aattgcttta tgctgttgat
    10381 taagtttgat aagtacattc ttatcgccgg aacgtttatc cagcccagca taaggtatat
    10441 tgacacgctg ctcccaaagc atccgtgaca tatctaacaa caccctatta tggctggctt
    10501 cagaaatggt cagatgaaac tgcttatcaa gcatataaaa ttcagccaca ttattttcat
    10561 gaatggaatt ttccattcgg aaatggagta actcaatttt attaattatt gtttcattat
    10621 tagccagtgc tgcaagtcgg gcacaatgac tatcaactaa atcacggaca taaagaattt
    10681 cttcgatagt gtaatcgact ggagagtgtt tattatcact gacaataatc ccattaccag
    10741 actgaataat aatccagcca gatatctcaa gaacaataag agcttctctc agcgatgaac
    10801 gactaactcc cagttgtttc gccagctcac gctctggagg taaaaaacta cctggcggaa
    10861 agacattatc attgatgagc ttaataataa gattcgctat cttttgatag agcctttcct
    10921 gtttaatttc tggaattaac atgtgcctcc cgctcgcttt tatcgttagt tatctgacga
    10981 attatcatat catacttggt tcggatctac tggtttcgcg tgacaatgac gaaaaatcag
    11041 cagtttgtca tcagtagcag aaagacgtct atccggtttc gatcctgact tttggcgtaa
    11101 taaaacgccc tccctttcta tcaataggtt atagtcagga taaaaatcat attcgtcgac
    11161 gccaatattg tccgtgaccg aaaacctttc actgactaag gcttggatac gcaaaccagc
    11221 cattttgtta cgtagatttt cgagaatgat tttagcgtgt gataattctg tttcgacaaa
    11281 caaaataata aatccttcgg caccatagag gaaaacataa gcactaatga gaatatgctc
    11341 acaaatcatc gaagagaaat ttttctgtgt attaccctcg gaattatgtc tataacgatt
    11401 attaattttc ttgaggataa tcaatatcca gcatggcaag ggagaattgt ttacgtgagt
    11461 gcaacgcgat agagattttc cgccgcataa tcgtcagaat aaagcgtcga tttaatagtt
    11521 atgtaagaga atctttaccg tttccatgaa tgtacctaag gtcattagtt cttttctgac
    11581 agcttccgga aaatttttat gtagagcaga aggcgtaaca agtctatcct ccctccgctt
    11641 ctttcatttt ctggtattgt gccggggata cgcgtggcaa tttccgtggc catggggggg
    11701 ggcatcttac tatacctacg ctgaagcgtg tgaaggtcag ggtatgatga catggttaaa
    11761 tactcacggc cactgcctga cctacttgag caacgtaccg aagctgctca gccccgataa
    11821 actaagaagc gcagcgctat gttcctgtca tccacgacag taaccaggcc ctgcagagta
    11881 ctatggtacg gttatcatac cggttcaccc acgcaaacca aaagcacaaa aaacggtgtt
    11941 ttcaccgttg aaagatagct gcttgccagt atccataatg aaaccttcca tgcactcagg
    12001 acgttgaatg gtaagcatcc ggtgaactcg cattgccggc cgttgtgaac cacgccattc
    12061 tgcaggttct tcctttatat gcaaaagaga gaaaactgat ggcaaaaaaa tgaccccggc
    12121 gcagcgacgc cagcactacg acgcctggcg cgtcagcggc atgtcccgga ccgcgtatgc
    12181 ccggcaacac ggcatcaaca acaaaacttt ctggcatcac tgccgcgcct tctccgctga
    12241 cgacgcccgt ggccccgctc cggctgataa cagaccagcc atcctgccgg tcaccctctc
    12301 cgtcagtgac actgccaccc tgaaacttca gtgcgcctgc gtcaccgcct ctccggccgg
    12361 catcgccgcc atcatccggg agcttaacct gtgctgagcc ctcattccct ctggctcgtc
    12421 cgcgagcctg ctgacatacg cgccggcatc gactccctga cgcgactcgc cactcaggcc
    12481 gccgggcatc cgccccggga aggcgaagcc ttcctcttca ccgggaaaaa acgcacccgc
    12541 atgaaactcc tgatgtggga ccgccacggc gtctggctct gcacccgccg cctgcaccag
    12601 ggcgccttcc gctggccccg cgacggcgac accacctggt cgctcacggc ggaacagttc
    12661 gcctggctta ccgccggcgt tgactggctg cgtctctctg ccagccccct gcagaggtgg
    12721 actgaataac ctcctgtgcc agaatcataa tacgggcagc ttcttatcag gatgttcccg
    12781 cccgcctctg tcatcatggc tgcatgacag atgacatcct gaacaccaca caaaaccccg
    12841 atgaactgcg ccgtctggca acagcgctgc tgacggcaca ggcatgcgaa tatgagcagc
    12901 gccttcataa cctgaatacc gtcaacacca cgctggaaca gcgcctccat aacctgaata
    12961 ccgtcaccac cacgctggaa cagcgtatcc atgaccttaa tgccgccatg caggcagaaa
    13021 aaaccgcata tgaacagcgc atccgggagc tggaggaggc cctgaagctg gcccaccagt
    13081 ggcgcttcgg gcgtaaaagc gagcgcctcc cggccagcca gaaaccactg gcagatgagg
    13141 acgcggccag cgatgaggct gatatcaccc ggcaactgag cgacctgctg ccggtgaagg
    13201 agaaaaccgg gaagaagccg gcccgtcacc ccctgccgcg acaggaaacc gtactcatgc
    13261 ctgagaccgg tagcacctgt ccggactgcg gaagtgcaat gcgacatatc cgcgacgagg
    13321 tgaatgaggt gctggagtat gtaccggcac acttcgtggt gaaacggacc gtgagaccgc
    13381 agtacagttg cccgtgctgc gacacggtgc acagtgccgt gctgccgccg gcagtcatcg
    13441 acaaagggca gccgggtccg ggtctgctgg cgcaggtggt gaccgcgaag gtgctggatc
    13501 acctgtcact gcagtggcag cagaagatat acgcccgtga aggggtacag ttgccggaaa
    13561 gcacgctgac ggactggttc gggccgacgg cggcggtgct gtcgccgctg gcggcagccc
    13621 tgaaacgtga cctgctcagg caaccggtgc tgcaggcgga cgagacgccg ctgcagatac
    13681 tggatacgcg gaaagggaaa gtccggaaag ggtacctgtg agcatacgtg agtgcggcgg
    13741 gcagtgcccg ggacatcgtg gtgtacgact gccgtccggg gcgtgcgggg cagtatgcgt
    13801 gtgagatgct gagcgggtgg tcggggactc tggtggctga cggttatgcc ggttaccggg
    13861 cgctgttccg tgacgggcag gaaggggccc ctccggcggc accgggtatc tgtgaggcgg
    13921 ggtgcatggc gcacgtgcgc agaaagttca tggagctgta cagaatgaac ggcagtccgg
    13981 gggcgaagga ggcgctgaaa cagatacggg cgctgtatat cctggagcag accatccggc
    14041 agcgtccggc agagcagaaa cggcgatggc gacggcggta cgcgaagccg cagatggagg
    14101 cgttccacag ctggctgagg gcgacggaaa agacgagcgc gccgggtggc aggctgcacg
    14161 gtgcggtgac gtatgccctg aagcgttggc cggcgctgga aacatacctg aatgacggac
    14221 gggtaccgct ggacaacaac cggagtgagc agatgatgcg tccggtggcg caggggcgga
    14281 agtcatggct gttcgcgggt tcgctgcggg gagaagagcg gctggcggag ctgctgacgc
    14341 tgctgcacac ggcgaggctg aacggtctgg agccagtagt ctggctgcgt gatgtgctgg
    14401 agaagctgcc gtcatggccg gcgtcccggc tggatgaact gctgccttac cgccatccgg
    14461 cggactgaat acgccctgcc ataacgccgg tgatcgcgcc atgcgagttc accggatgct
    14521 tacgttgaat gtacgttttt gggatttact gacggatatg aataaccggc ccatgaagga
    14581 gtacggcaaa accagcgcag aacacttccg tatgcgctca tttggggcgg gatttgcaca
    14641 gtattcagct tccagaatct gtacactctt ccactcacac agcttcctca aaatacagcc
    14701 tattgctcta cgcttctctc tgtagaacac ctgtcttcgg tattttggcg caaaaactat
    14761 gtgatattta cagttccaag cggctcgttg ccattcgcca gtccttcaac ggaatcgtcc
    14821 atttctggga cgcagactgg attgccagcc acaccacttt tttcaccgag tcgtctgtcg
    14881 ggaacacttt acgctttttg atcgcatggc ggatcacgct gtttagcgac tcgatggcat
    14941 tcgtcgtata gatcactttg cggatgtccg ttggataagc gaagaacgtg gcaagattcg
    15001 gccagttagc ctgccagctt cggctgtcag cgccggtgaa acatctgcgt catacagttc
    15061 tttgaacgca gcagctatct cacgagtggt catccctttg gcatacaacg agaggatctg
    15121 gttatccatc ccggtaatac gggtctgatt tttctttacc agttgtggtt cgaaggtacc
    15181 gtcacgatcg cgcggagtac gcagttccag tggaccgtcg cctgtgataa cggtctttgt
    15241 ggaataaccg ttgcgggagt tagctcctag tctgggctga tttttctcat acccaagatg
    15301 gtgtgtcatc tcagcattga gagcggcttc aacgctgagc tttttcagca gccgatcaaa
    15361 ctgactgagg tcttcagagg ttttgaggtt tttggccagt tcgttagcca gagcctgtaa
    15421 ctgtttttca tccataaatt aaccttcata tgatgcagga ttgaacatat caaaatcagg
    15481 cgattacaca aatctatgta caggttcagc cgctttatta tcgagttcgg tgaccgccag
    15541 gacggtcact tctgagaaaa ggcatttaca cagaatctta aacaggttca cgcagcactg
    15601 gcgtcagggc attgattgtc gctttcactg atttgctccg gtttcccgtg gtcagactgc
    15661 gcactttctc cttcagcctg ttcacactcg tcagggctat tttcagcttc aactgtttgt
    15721 gccatgtcat actgtacccg aggaacttct gctcccacgg gcgcgccacc gcgctcttct
    15781 tctcattcac tttctgcttc agtttgttct ctacgacgtc ctgataccat ccagcaatgg
    15841 ccgccctgcg gcatgccttc ctgccatttc tctctttgcc cgtcccggac tatttcctct
    15901 ttcaagtagc ggcgtatcag cctcagcacc cgcctgtact ttatcgtact ggccagacgc
    15961 gtcatcagga gtctgtgatc cacacggtcg aagaacttct ccagatttat atccaccacc
    16021 caccgtttgc tgccccgtat ataatgctgt gcctattgca ctgcctgcca tacgttgcgt
    16081 cccagccgga aaccgtgcct agagtctgag aagcttttgt ccacgatggc gcttaaatgt
    16141 tgcgctatag ctatagcctg ctggataggc ctatccacca ctgtcgggat gcctaaggtt
    16201 ctcacgccgc catcatgcag ctctgacg
//
LOCUS       DACAOP010000099        15719 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.099, whole genome shotgun sequence.
ACCESSION   DACAOP010000099 DACAOP010000000
VERSION     DACAOP010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15719
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.099"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            331..750
                     /gene="umuD"
                     /locus_tag="IT892_003583"
     CDS             331..750
                     /gene="umuD"
                     /locus_tag="IT892_003583"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HAP3136750.1"
                     /translation="MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLL
                     IQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIVIAAVDGEFTVKKLQLR
                     PTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR"
     gene            750..2018
                     /gene="umuC"
                     /locus_tag="IT892_003584"
     CDS             750..2018
                     /gene="umuC"
                     /locus_tag="IT892_003584"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V subunit
                     UmuC"
                     /protein_id="HAP3136751.1"
                     /translation="MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEA
                     KALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADMSNRVMSTLEELSPRVEIYSIDE
                     AFCDLTGVRNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
                     GGVVDLSNLERQRKLMSALPVDDVWGIGRRISKKLDAMGIKTVLDLADTDIRFIRKHF
                     NVVLERTVRELRGEPCLQLEEFAPTKQEIICSRSFGERITDYPSMRQAICSYAARAAE
                     KLRSEHQYCRFISTFIKTSPFALNEPYYGNSASVKLLTPTQDSRDIINAATRSLDAIW
                     QAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMTVMDTLNAKEGRGTLYFA
                     GQGIQQQWQMKRAMLSPRYTTRSSDLLRVK"
     gene            complement(2064..2594)
                     /gene="dsbB"
                     /locus_tag="IT892_003585"
     CDS             complement(2064..2594)
                     /gene="dsbB"
                     /locus_tag="IT892_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein DsbB"
                     /protein_id="HAP3136752.1"
                     /translation="MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLC
                     IYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFA
                     TCDFMVRFPEWLPLDKWVPQVFVASGDCAERQWDFLGLEMPQWLLGIFIAYLIVAVLV
                     VISQPFKAKKRDLFGR"
     gene            complement(2740..4281)
                     /gene="nhaB"
                     /locus_tag="IT892_003586"
     CDS             complement(2740..4281)
                     /gene="nhaB"
                     /locus_tag="IT892_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)/H(+) antiporter NhaB"
                     /protein_id="HAP3136753.1"
                     /translation="MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAG
                     WLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFM
                     VAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAAFLSAFLDALTVVAVVISVAVG
                     FYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTM
                     VGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKV
                     REVLQQFDDQSRHQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSL
                     TGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLF
                     YIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPN
                     GQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMG
                     WIATL"
     gene            4502..5221
                     /gene="fadR"
                     /locus_tag="IT892_003587"
     CDS             4502..5221
                     /gene="fadR"
                     /locus_tag="IT892_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid metabolism transcriptional regulator
                     FadR"
                     /protein_id="HAP3136754.1"
                     /translation="MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVT
                     RTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLL
                     SVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPI
                     YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHE
                     SGEIWHRMQKNLPGDLAIQGR"
     gene            complement(5273..6805)
                     /locus_tag="IT892_003588"
     CDS             complement(5273..6805)
                     /locus_tag="IT892_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HAP3136755.1"
                     /translation="MATIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYRLDTY
                     PHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNP
                     CIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFRSWTDASSIVDYLIFARKYITEC
                     EERYGVDEVERLLDSCHALMNYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWR
                     TLPKREEEKTVAEARRYPSEPQENLLYFMEKNAPLLESWQREILRIVRKVSQYFYPQK
                     QTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINP
                     YALGFAMFQDIKRICQSPTEEDKYWFPDIAGSDWLETLHFAMRDFKDESFISQFLSPK
                     VMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRNRLSSQYNLSNLEPNIQIWNVDLR
                     GDRSLTLRYIPHNRAPLDRGRKEVLKHVHRLWGFDVMLEQQNEDGSIELLERCPPRMG
                     NL"
     gene            7135..8433
                     /locus_tag="IT892_003589"
     CDS             7135..8433
                     /locus_tag="IT892_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HAP3136756.1"
                     /translation="MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANA
                     GQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYM
                     ENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDA
                     GVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKF
                     RFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYS
                     LTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMV
                     VRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQ
                     LLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS"
     gene            8443..9513
                     /gene="dadX"
                     /locus_tag="IT892_003590"
     CDS             8443..9513
                     /gene="dadX"
                     /locus_tag="IT892_003590"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolic alanine racemase DadX"
                     /protein_id="HAP3136757.1"
                     /translation="MTRPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIE
                     RIWSAIGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHS
                     NWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
                     AEAEHPDGISGAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPS
                     GQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGY
                     PRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAA
                     AAGTVGYELMCALALRVPVVTV"
     gene            complement(9899..11635)
                     /locus_tag="IT892_003591"
     CDS             complement(9899..11635)
                     /locus_tag="IT892_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415709.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HAP3136758.1"
                     /translation="MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGML
                     AGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLI
                     TSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
                     NDPMAVFLTITLIAMIQHHESNISWMFIVDILQQFGLGIVIGLGGGYLLLQMINRIAL
                     PAGLYPLLALSGGILIFSLTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAW
                     LAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERV
                     FISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKV
                     VVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDN
                     QLLHPTGSTRLREGDVLCVIGRERDLSALGKLFSQSPPVALDQRFFGDFILEASAKYA
                     DVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLK
                     IGVRVAEEEAES"
     gene            complement(11730..12644)
                     /gene="ldcA"
                     /locus_tag="IT892_003592"
     CDS             complement(11730..12644)
                     /gene="ldcA"
                     /locus_tag="IT892_003592"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muramoyltetrapeptide carboxypeptidase"
                     /protein_id="HAP3136759.1"
                     /translation="MSLFHLIAPSGYCIKQHAALRGIQRLTDAGHQVNNVEVIARRCE
                     RFAGTETERLEDLNSLARLTTPNTIVLAVRGGYGASRLLADIDWQALVARQQHDPLLI
                     CGHSDFTAIQCGLLAHGNVITFSGPMLVANFGADELNAFTEHHFWLALRNETFTIEWQ
                     GEGPTCRAEGTLWGGNLAMLISLIGTPWMPKIENGILVLEDINEHPFRVERMLLQLYH
                     AGILPRQKAIILGSFSGSTPNDYDAGYNLESVYAFLRSRLSIPLITGLDFGHEQRTVT
                     LPLGAHAILNNTREGTQLTISGHPVLKM"
     gene            12744..13355
                     /gene="emtA"
                     /locus_tag="IT892_003593"
     CDS             12744..13355
                     /gene="emtA"
                     /locus_tag="IT892_003593"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415711.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     EmtA"
                     /protein_id="HAP3136760.1"
                     /translation="MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQ
                     KAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEP
                     TTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
                     RKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDAM"
     gene            complement(13357..14091)
                     /locus_tag="IT892_003594"
     CDS             complement(13357..14091)
                     /locus_tag="IT892_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein YcgR"
                     /protein_id="HAP3136761.1"
                     /translation="MSHYHEQFLKQNPLAVLGVLRDLHKAAIPLRLSWNGGQLISKLL
                     AITPDKLVLDFGSQAEDNIAVLKAQHITITAETQGAKVEFTVEQLQQSEYLQLPAFIT
                     VPPPTLWFVQRRRYFRISAPLHPPYFCQTKLADNSTLRFRLYDLSLGGMGALLETAKP
                     AELQEGMRFAQIEVNMGQWGVFHFDAQLISISERKVIDGKNETITTPRLSFRFLNVSP
                     TVERQLQRIIFSLEREAREKADKVRD"
     gene            14292..14546
                     /locus_tag="IT892_003595"
     CDS             14292..14546
                     /locus_tag="IT892_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP3136762.1"
                     /translation="MGIIAWIIFDLIAGIIAKLIMPGRDGGGFFLTCILGIVGAVVGG
                     WLATMFGIGGSISGFNLHSFLVAVVGAILVLGIFRLLRRE"
     gene            14724..15164
                     /locus_tag="IT892_003596"
     CDS             14724..15164
                     /locus_tag="IT892_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136763.1"
                     /translation="MIQKINILDSSQSGVKNGADSEAVLAALTEHLELINPSGRLSQN
                     TRSAMLQLREEEWSEFFFWLLNSLECLDYVIINLTPESKKTLMSEHRNNIQVAIDALY
                     SQRRRKSPGDESETLTRRNDAIFGNHVWQTFAQYFPSGLEKPSV"
     gene            complement(15243..>15719)
                     /locus_tag="IT892_003597"
     CDS             complement(15243..>15719)
                     /locus_tag="IT892_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136764.1"
                     /translation="PLYVNAAAKDRANKMATATKTHLLQPGGLNTTSVKSGQQWDAPN
                     GWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGGG
                     GEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQPSTKEAQPTP"
BASE COUNT         3971 a         3908 c         4104 g         3736 t
ORIGIN      
        1 tgttttacaa ctattaataa attttacttc atctaattca tagttagccg ggcgggatgc
       61 gtcaatgtct ttatttctat taatatgata aatatcaaac aatgtttaat gtcattatgg
      121 cgaatgcttc tattctattt tttagccggg tgatattttt catttctgct ggatgagcgt
      181 cgtcgccaga aggccacgtg agcacaagat aagagaacga aaaatcagca gcctatgcag
      241 cgacaaatat tgatagcctg aatcagtatt gatctgctgg caagaacaga ctactgtata
      301 taaaaacagt ataacttcag gcagattatt atgttgttta tcaagcctgc ggatctccgc
      361 gaaattgtga cttttccgct atttagcgat cttgttcagt gtggctttcc ttcaccggca
      421 gcagattacg ttgaacagcg catcgatctg aatcaactgt tgatccagca tcccagcgcg
      481 acttacttcg tcaaagcaag tggtgattct atgattgatg gtggaattag tgacggtgat
      541 ttactgattg tcgatagcgc tattaccgcc agccatggtg atattgtcat cgctgctgtt
      601 gacggcgagt ttacggtgaa aaaattgcaa ctacgcccga cggtacagct tattcccatg
      661 aacagcgcgt actcgcccat taccatcagt agtgaagata cgctggatgt ctttggtgtg
      721 gtgatccacg tcgttaaggc gatgcgctga tgtttgccct ctgtgatgta aacgcgtttt
      781 atgccagctg tgagacggtg tttcgccctg atttatgggg taaaccggtg gttgtgctat
      841 cgaataatga cggttgcgtt atcgcccgaa acgctgaggc aaaggcgctt ggcgttaaaa
      901 tgggcgatcc ctggttcaaa caaaaagatc tgtttcgtcg ctgtggcgtg gtttgcttta
      961 gcagcaatta tgagctttac gcagacatga gcaatcgggt gatgtcgacg ctggaagagc
     1021 tatcgccccg cgtcgagatt tacagtattg atgaggcatt ctgcgatctg acaggtgtgc
     1081 gtaattgtcg cgatctgact gattttggca gagaaattcg cgcaacggtg ctacaacgta
     1141 cccatcttac tgttggtgtg gggatcgccc agaccaaaac gctggctaag cttgccaatc
     1201 atgcggcaaa aaaatggcag cggcagacgg gtggggtggt ggatttatca aatctggaac
     1261 gccagcgtaa attaatgtct gctctccccg tggatgacgt ctgggggatt ggacggcgga
     1321 tcagcaaaaa actggacgcg atggggatca aaaccgttct cgatttggcg gatacagata
     1381 tccggtttat ccgtaaacat tttaatgtcg tgctcgaaag aacggtgcgt gaactgcgcg
     1441 gcgaaccctg tttgcaactg gaagagtttg caccgacgaa gcaggaaatt atctgttccc
     1501 gctcgtttgg tgaacgcatc acggattatc cgtcgatgcg gcaggccatt tgtagttacg
     1561 ctgcccgggc ggcggaaaaa cttcgcagcg agcatcaata ttgtcggttt atctccacgt
     1621 ttattaagac gtcaccattt gcgctcaatg aaccttatta cggcaatagc gcgtcggtaa
     1681 aactgctgac gcccactcag gacagcaggg atatcattaa cgctgctacg cgatctctgg
     1741 atgccatctg gcaagcgggc catcgttacc aaaaagcggg cgtgatgctg ggggatttct
     1801 tcagtcaggg agtcgcgcag ctcaatttat tcgatgacaa cgcaccgcgc cccgggagtg
     1861 agcaattgat gacggtaatg gatacactga atgctaaaga gggcagagga acactctatt
     1921 ttgccgggca ggggatccag caacaatggc agatgaagcg agccatgctt tcaccacgtt
     1981 atacaacgcg aagttctgat ttactgaggg tcaaataaat atagcggcag gaaaaaagcg
     2041 ctcccgcagg agcgccgaat ggattagcga ccgaacagat cacgtttttt cgctttaaac
     2101 ggctgggaaa tcaccaccag cactgcgaca atcaggtaag cgataaaaat accgagcagc
     2161 cactgcggca tttccagacc taaaaaatcc cactgacgct cggcgcaatc gccagaggcg
     2221 acaaacactt gcggcaccca cttatccagc ggcagccatt ccgggaaacg aaccataaaa
     2281 tcacaggtgg caaacggcga aggatagagc tgaagcatgg tgtgctcgta agttaactgc
     2341 acaccgcgga acgcactata caaccagata accatcgcta cataacgcag cggagttttc
     2401 ggggcgatcg cgccaatcag cgcagcaccc agaacgccga ataacgcgca gcgttcataa
     2461 atacagagca cgcaaggttt cagtaacatc acatgctgga accacagcgc cgtcagttcc
     2521 agtgccagag cagtaaacgc catcaacagc cacgcgcccc ggccttgtga acattggttc
     2581 aaaaatcgca acataatcat ttccctgcaa tatgcataga gtgcgcagtt taaaccaatt
     2641 cattcgctgc gccaccagga ggcagcaaaa ataggacgca attggacaat tatcgggcga
     2701 aaaggcaaac cgggcattta tatgcccggt aagttgttat caaagcgttg ctatccagcc
     2761 catttgcata aaccattcgg ttacaggggc aagcgtaaac tcgacgcaga gcaagccgac
     2821 gagtgtcagg acgagggtgt aaggcagggc catccacacc atgcggccat aagagaggcg
     2881 aatcaatggc gcgagtgcag aggtcagcag gaacaggaac gcagcctgac cgttcggcgt
     2941 agcgacggag ggcagattgg taccggtatt aatggcgacc gccagcagct cgtattgctt
     3001 caacgtgata gcgccacttt ccattgccgc tttcgcttcg ttgatataaa tcgtccccac
     3061 gaagacgtta tccgaaatgg atgacagcag accgttgaaa atatagaaca gcgacagctg
     3121 agcatgttcc gatgcctgca acacaaactg aataattggc gaaaacagtt gttggtcgat
     3181 aatcaccgcg actaccgaga aaaacaccgt caacagtgcg gtgaatggca gagattcggt
     3241 gaaggcttta ccgatagcat gctcatcggt gacaccggtc aatgatgttg ccagaataat
     3301 gactgacaaa ccaatcaagc caacttccgc cagatgcaac gccagcgcag tcaccagcca
     3361 gacgccaata atcgcctgga caatcagacg gattttatcc tgacgggtac gctggtggcg
     3421 gctttgatcg tcaaactgtt gcaacacttc gcggactttc tccggcagcg tttcaccgta
     3481 gccaaaccaa cgcagcttct ctaccagcag gcaggttaac aggccacaaa tcagaaccgg
     3541 aacggtcacc ggcgacatgc gcaggaagaa atcgccaaaa tgccagccag ccgctttagc
     3601 gatgatcagg ttctgtggtt cgcccaccat ggtcattacg ccgcctaatg cggtgccgac
     3661 accggcatgc atcatcaggc tacgcagaaa gccacggaac tgttccagaa ccactttgta
     3721 atgcttgtcg atatgactat cgtcttgcag gtcggtgtct tcggtacggg aagaggctac
     3781 gcggtgataa ataccataaa aaccgactgc aacgctgatc accaccgcca cgacggttaa
     3841 ggcatcgagg aacgcggaga ggaacgcagc cgccacgcaa aaagagagcg acagcagcat
     3901 tttggagcga atgcttaaca gcaaacgggt aaatatgaac agcaacagct gtttcataaa
     3961 atagataccc gccaccataa acatcagtaa cagcaagact tcaagatttg ccgccacctc
     4021 ttcacggacg tgttccgcgc tggtcatgcc gatgaatacc gcttcgatag ccaacagacc
     4081 accggggagc agcgggtagc atttcagggc catcgccaga gtgaaaataa attccgctac
     4141 cagcaaccag cccgcgacga aagggctgat gaggaaaatt aacgggttta cgattaagaa
     4201 aatgatgagg gcgagtttgt accagtcggg ggactggccc aaaaaattgc gccatagcgc
     4261 gcggccccag gagatctcca tgatggtttc ccttacctta caaataatca atgatgtttt
     4321 tatgtttaaa cgcaaagctt aacggtcagg caggagtgag gcaagtcttg atagtcaagg
     4381 ggaaagaaat gcggaaaatg aagccttgat ccctttttct tctttttgtc tgctatcagc
     4441 gtagttagcc ctctggtatg atgagtccaa ctttgttttg ctgtgttatg gaaatctcac
     4501 tatggtcatt aaggcgcaaa gcccggcggg tttcgcggaa gagtacatta ttgaaagtat
     4561 ctggaataac cgcttccctc ccgggactat tttgcccgca gaacgtgaac tttcagaatt
     4621 aattggcgta acgcgtacta cgttacgtga agtgttacag cgtctggcac gagatggctg
     4681 gttgaccatt caacatggca agccgacgaa ggtgaataat ttctgggaaa cttccggttt
     4741 aaatatcctt gaaacactgg cgcgactgga tcacgaaagt gtgccgcagc ttattgataa
     4801 tttgctgtcg gtgcgtacca atatttccac tatttttatt cgcaccgcgt ttcgtcagca
     4861 tcccgataaa gcgcaggaag tgctggctac cgctaatgaa gtggccgatc acgccgatgc
     4921 ctttgccgag ctggattaca acatattccg cggcctggcg tttgcttccg gcaacccgat
     4981 ttacggtctg attcttaacg ggatgaaagg gctgtatacg cgtattggtc gtcactattt
     5041 cgccaatccg gaagcgcgca gtctggcgct gggcttctac cacaaactgt cggcgttgtg
     5101 cagtgaaggc gcgcacgatc aggtgtacga aacagtgcgt cgctatgggc atgagagtgg
     5161 cgagatttgg caccggatgc agaaaaatct gccgggtgat ttagccattc aggggcgata
     5221 atcccttccg tttaaagagc aaacccctca aacgaggggt tttttgttgt ttttacagat
     5281 ttcccattct tggcgggcaa cgttccagca actcgatgct gccgtcttcg ttttgctgtt
     5341 cgagcatcac atcaaatccc cacaggcgat gcacatgctt caggacttct ttgcgccccc
     5401 gatccagcgg tgcgcgatta tgtggaatat aacgcagcgt cagcgaacgg tcgccgcgca
     5461 aatccacgtt ccagatctga atattcggct ccagattact taagttatat tgcgacgata
     5521 accggttacg gatctcccga taaccttctt cattatgaat agcggaaatc tccagataat
     5581 tatgccgatc gtcatccagc acggtgaaga agcggaaatc acgcatcact ttcggtgaca
     5641 ggaactggct gataaaactc tcatctttga aatcacgcat cgcgaaatgc agcgtttcca
     5701 gccagtcgga accggcgata tccgggaacc agtatttgtc ttcttccgtt ggcgactgac
     5761 aaatccgttt aatatcctgg aacatggcga acccgagggc atacgggttg atgccgctgt
     5821 accacgggct gttatagggg ggctggaaga ccacattggt gtggctgtgc aaaaactcca
     5881 gcataaaacg ttccgttact ttcccttcat catacagatg gttaaggatg gtgtagtgcc
     5941 agaaggtcgc ccagccttcg ttcatcacct gagtctgttt ttgcggataa aaatactggc
     6001 tcaccttacg cacaatacgc aggatttcac gctgccatga ttccagcagt ggcgcatttt
     6061 tctccataaa atagagcagg ttttcttgtg gttcggacgg atagcggcgc gcttcagcaa
     6121 ccgttttctc ttcctcgcgc ttcggcaggg tacgccagag catattgacc tgactttgca
     6181 gatactcttc gcgacttttc tgccgggctt tctcttcttg cagcgagatt ttttgcgggc
     6241 gtttgtaccg gtccacgccg tagttcatca gcgcgtggca cgagtccaga agccgttcta
     6301 cttcatcaac gccataacgc tcttcgcact cggtaatata tttacgggca aaaatcagat
     6361 aatcgacaat cgaactggcg tcggtccagc tacggaataa gtaattgttt ttgaagaaag
     6421 agttatgccc atagcaggca tgagccatca ccagcgcttg catggtaatg gtgttctctt
     6481 ccatcaggta agcgatacac gggttagagt taatgacgat ttcataggcc agtccttgct
     6541 gaccgtgctt atacagccgt tcagtctcga taaacttttt accgaatgac cagtgcggat
     6601 agttaattgg catgccgacg ctggagtagg catccatcat ctgttctgag gttatcactt
     6661 caatctggtg cgggtaggta tccagccggt agagtttcgc cacccggtct atctctgcca
     6721 gataaacatc cagcaggtcg aacgtccagt cgggtccatc gctcaaacgt gtggtgtcct
     6781 tattcataga atcgatcgtc gccatacgcg cacctcattg ttgtcggcgc tctctgtgtg
     6841 gagcacctca tttcaagcat agaacacctg ttaaaaaccg cgtcgccgga gaattttttt
     6901 ctttgcgatt tcttattatc agagtgccac taatccgctt ctgaacggaa ttttatgctg
     6961 gataaaaagg gcgttcagca ggagatacta aagacgccat attgccgcag agtcagggag
     7021 atgtgagcca gctcaccata aaaaagccgt atgttgaata atattttcaa ctgagttatc
     7081 aagatgtgat tagattatta ttcttttact gtatctaccg ttatcggagt ggctatgcga
     7141 gttgtcatac tgggaagtgg tgtggtaggc gttgccagcg cctggtactt aaatcaggca
     7201 ggacatgagg tcaccgtcat tgatcgggag ccgggggccg ccctggaaac cagtgccgcg
     7261 aatgccgggc aaatctcccc cggatatgct gcaccgtggg cggcaccagg tgtgccttta
     7321 aaagcgatta aatggatgtt ccagcgccat gcgccgctgg cggttcgtct cgacggtacg
     7381 cagttccagt tgaaatggat gtggcaaatg ttacgtaact gcgacaccag ccactacatg
     7441 gaaaacaaag ggcggatggt gcgtctggcg gaatacagcc gtgattgcct gaaagcattg
     7501 cgcgccgaaa ccaatattca gtatgaaggg cgtcagggtg ggacgctgca actgttccgt
     7561 accgaacaac agtatgaaaa tgcgacccgc gatatcgccg tgctggaaga tgccggcgta
     7621 ccgtatcagc tgctggaatc cagccgcctg gcggaagtgg agcccgcgct ggcagaagtg
     7681 gcgcacaaac tgacgggcgg cctgcagtta cccaatgatg aaaccggaga ctgtcagcta
     7741 tttacccaga atctggcgcg gatggcggag caggcggggg ttaaattccg ctttaatacg
     7801 cccgttgacc aactgctttg cgacggcgag caaatctacg gcgtgaagtg tggcgatgaa
     7861 gtgattaagg ccgatgcgta tgtgatggcg tttggttctt actcgacggc gatgctcaaa
     7921 ggcattgttg atattccggt gtatccgctg aaaggctact cgctgaccat tccaattgcg
     7981 caggaagatg gtgcgccggt atccaccatt cttgatgaaa cctacaaaat cgccattacc
     8041 cgtttcgata accgcattcg tgttggcgga atggcggaga ttgttggttt taataccgag
     8101 ctgttgcaac cgcgtcgtga aacgctggag atggtggttc gcgatctcta tccacgcggc
     8161 ggtcatgtcg agcaggcgac tttctggact ggtctgcgcc cgatgacgcc agacggcacg
     8221 ccggttgtcg ggcgtacacg ctttaaaaat ctgtggctga ataccggtca cggcacgctc
     8281 ggctggacga tggcttgcgg ttccggtcag ttgttaagcg atctgctctc tggtcgcacg
     8341 ccagcgatcc catatgagga tctaagcgta gcgcgctaca gccgtggatt tacgccatca
     8401 cgtccgggcc atttacatgg cgcacacagc taaggaaacg agatgacccg tccgatacag
     8461 gccagcctcg atctgcaggc attaaaacag aatctgtcca ttgtccgcca ggccgcgacg
     8521 cacgcgcgcg tctggtcggt ggtaaaagcg aacgcttacg ggcatggtat tgagcgtatc
     8581 tggagcgcga tcggggccac cgatggcttt gcattgctta acctggaaga ggcaataacg
     8641 ttacgtgagc gcggctggaa aggaccgatc ctgatgctgg aaggattttt ccatgctcag
     8701 gatctggaga tttatgacca gcaccgcctg accacctgcg tacacagcaa ctggcagctc
     8761 aaagcactgc aaaatgcgcg gctaaaagca ccgttggata tttatcttaa agtgaacagt
     8821 gggatgaatc ggttgggctt ccagcccgat cgcgtgctta ccgtctggca gcagttgcgg
     8881 gcaatggcga atgttggcga aatgaccctg atgtcgcatt ttgccgaagc ggaacatcct
     8941 gatggaattt ccggcgcgat ggcgcgtatt gagcaggcgg cggaggggct ggagtgtcgg
     9001 cgttcgttgt ccaattcggc ggcgactctg tggcacccgg aagcgcattt tgactgggtt
     9061 cggcctggca ttattttgta tggcgcttcg ccgtccggtc agtggcgtga tatcgccaat
     9121 accggattac gtccggtgat gacgctaagc agtgagatta ttggtgtcca gacgctaaaa
     9181 gcgggcgagc gtgtgggcta cggcggtcgc tatactgcgc gcgatgaaca gcgaatcggc
     9241 attgtcgccg cagggtacgc cgacggttat ccgcgccacg cgcctaccgg tacccctgtt
     9301 ttagtggacg gcgtgcgcac catgacggtg gggaccgtct cgatggatat gctagcggtc
     9361 gatttaacgc cttgcccgca ggcgggtatt ggtacgccgg ttgagctgtg gggcaaggag
     9421 atcaaaattg atgatgtcgc cgccgctgcc ggaacggtgg gctatgagtt gatgtgcgcg
     9481 ctggcgctac gcgtcccggt tgtgacggtg taacttgttg taagccggat cggaggcaac
     9541 gtcttctggg tgcaaaaaaa tcatccatcc ggctggtcag caactgtagt tgttaatgtg
     9601 acagagccat tgcccatgat agtgtccatt aaaaggatgg acactatttc cccggaacct
     9661 gaactcaccg cacaggcgtt ctacataaaa cgcttacgct tcattgttga ctcgaactcg
     9721 acttcagata aatcacgctt tacccttgat ggagcctgta catagatttg tgtaattgcc
     9781 tgattttgat atgttcaatt caacatcaaa tgaaggttaa attatggacg acaaacaatt
     9841 gcaggctcag gctgcgttca gcaaagcatc gcaaccggcg atagatgctt cattaaattt
     9901 aagattcagc ttcctcttca gccacccgta cgccaatctt caacacttca ttatcttctt
     9961 tctcggccac cgtccagatc atcccggcaa actctacctg gtcaccgaca accggtgccg
    10021 cgcctaacaa ctgctggaca atttcaccca gcgtttgctg cttatcacga tattctcgcc
    10081 cgtcttccag gccatatatc agcgcaacat cagcatattt ggcgctggct tcgagaatga
    10141 agtcaccaaa gaagcgttga tccagcgcga ccggcggcga ctggctgaac agtttaccga
    10201 gcgccgaaag atcgcgttcc cgaccaatta cacacaacac atcgccttcg cgcagtcggg
    10261 tgctgccggt aggatgaagc aactggttat cacgaaacag tgccgcaata cgcgtctctt
    10321 ttggcatatg caaatcgcgc agtgccgcgc ccacgcacca tttatcggca ctcaattgat
    10381 aaacaaactg ctcccacgga ttttccggat gaatatccag cccaacgcgt gacaccggac
    10441 gtcccactgg cggaaccacc actttggctt ttttagccgc ccacgagagt gatgttccct
    10501 gcaagagcag tgaaaccaga accacaaaga aggcgacatt aaagaacaga cgtgcattct
    10561 ccagccccgc catcatcggg aacacggcca ggatgattgg caccgcgccg cgtaatccta
    10621 cccagctgat aaacacgcgc tcacgcagat tgaaaccgcg gaaggggagc aatccagcaa
    10681 ataccgaaag gggacgggcg aagaatatca tccatgcgga caaaatgagc gccggaatgg
    10741 caataggcag cagatcgctt gggttaacca acagccccag caccaggaac atggcgattt
    10801 gcgccagcca ggcgaggccg tcgaaatttt gcaggatgcc gtagcggttg cgaatagggc
    10861 gattacccag cagaaaaccg cacagataca ccgccagaat accgctacct tccagcgcag
    10921 tagttaatga gaaaatcaga ataccgccac ttaatgccag caatggatat aatccggcgg
    10981 gcagggcgat gcggttgatc atttgcagta gtaaataacc gccgccaaga cctattacaa
    11041 tgcccagacc aaattgttgc agaatatcga caatgaacat ccagctaata ttgctctcat
    11101 gatgctggat catcgcaatt agggtaatcg tcagaaagac cgccattgga tcattactgc
    11161 cggattcaat ttccagcgtc gagccaacac gttcgttaag ccccttacca cccagcagag
    11221 aaaagaccgc tgcagcatcg gtagagccga cgatagcgcc gattaataag ccttcaatca
    11281 aatcaagatt aaacagccac gccgccatca tgccggttaa accagaggtg ataagcacgc
    11341 ccagcgtcgc cagcgacagt gccggtccta acgccacacg aaaggaactg gcctgagtgc
    11401 gcatcccgcc gtcgagcaaa ataatcgcca gtgccaggtt acttaccatg taggcgaagg
    11461 ggtaattatc aaacgggata ccgccgacgc catcgactcc tgccagcatg ccgatcgcca
    11521 gaaaaataac cagaatagga atgccaagac gggaagaaaa tgaactaagt aatatactgc
    11581 tggtgacaag gatggatcct aagatgaaaa ggctaattat tgttgtggca tccaacggtc
    11641 ggttactcct gattacgctg tctcttatat aaaccctacc atattagcgg cagagacagc
    11701 gttttactta gccctgaagc gtgatttttt tacattttaa gaacaggatg accgctaatc
    11761 gtcaactgag tgccttcccg ggtgttattc agaatggcat gtgcgcccaa cggcagcgta
    11821 accgtgcgtt gttcatgacc aaaatcgagg ccggtaatga gtggaatcga caggcgggaa
    11881 cgcaaaaacg cgtacactga ctccaggttg taacctgcgt cataatcatt gggcgtgctg
    11941 ccgctaaagc taccgagaat aatcgccttc tgacgtggca aaattcccgc atgatagagc
    12001 tgcaacagca tacgttcgac ccggaaaggg tgctcgttaa tatcttccag caccagaata
    12061 ccgttctcaa tttttggcat ccacggtgta ccgatcagtg aaatcagcat cgcaagattg
    12121 cctccccaca acgtgccttc ggcccgacat gtcgggcctt ccccttgcca ttcaatggtg
    12181 aaggtttcat tgcgtaacgc cagccagaaa tggtgctcgg taaaggcgtt cagttcatcc
    12241 gcgccaaagt ttgctaccag catggggccg ctaaaggtga tgacattgcc atgcgccaga
    12301 agaccgcact gaatggcggt aaaatcgcta tgtccgcaaa tgagcaacgg gtcatgttgt
    12361 tggcgagcca ccagtgcctg ccagtcaata tctgccagta aacgactggc accgtaaccg
    12421 ccgcgtacag ccagcacgat ggtgttgggg gtagtcagtc tggcaaggga attgagatct
    12481 tccagacgct ctgtttccgt acccgcaaaa cgctcacaac gacgggcaat aacctcgacg
    12541 ttattgactt gatgccccgc gtcggtaagg cgctggatac cacgcagcgc ggcgtgctgt
    12601 ttaatgcagt aacccgatgg ggcaattaag tgaaacagag acatggcaat tccttgctga
    12661 caacagaaac gaaatgtata tcatgccgct taggtgtgcc gttgtcacct caacggcgat
    12721 tccaggctat aaggatagaa gaagtgaaat tgagatggtt tgcctttttg attgtgttat
    12781 tagcgggttg ttcatcaaag catgactata cgaacccgcc gtggaacgcg aaagttccgg
    12841 tgcaacgtgc gatgcagtgg atgccaataa gccagaaagc cggtgcagcc tggggcgtcg
    12901 atccacaatt gatcacggcg attatcgcta tcgaatcggg tggtaatccg aacgcggtga
    12961 gtaaatcgaa tgccattggt ttgatgcagt taaaagcttc aacctccgga cgtgatgttt
    13021 atcgccgtat gggctggagt ggtgagccga cgaccagcga gctgaaaaat ccagagcgta
    13081 atatttcaat gggggcggct tacctgaata ttctggaaac cggcccgctg gcaggcattg
    13141 aagatccgaa ggtactgcaa tatgcgctgg tggtgtcata cgctaacggg gcaggtgcgc
    13201 tgctacggac tttctcgtca gatcggaaaa aggcgatcag caaaatcaac gatttggatg
    13261 ctgacgagtt cctcgaacac gtagcgcgaa atcaccctgc gccgcaggct ccgcgctata
    13321 tctacaaact tgagcaggca ctggacgcga tgtaaatcag tcgcgcactt tgtccgcttt
    13381 ttcccgggct tctcgctcga gagagaaaat aatccgctgt aattgccgct ccaccgtcgg
    13441 gctgacgtta agaaaacgga agctcagacg gggagtggtg atggtttcat tcttgccatc
    13501 aatcactttg cgctcgctga tggagattaa ctgggcgtca aagtgaaaaa caccccattg
    13561 ccccatgttg acttcaatct gagcgaagcg catgccttct tgtaattcgg caggctttgc
    13621 tgtttccagt aatgcgccca tgccgcctaa cgacaaatca tacaggcgga aacgtaacgt
    13681 actgttatcc gccagtttgg tctggcaaaa ataaggcgga tggagtgggg cggagatgcg
    13741 gaaatatcgg cgtcgttgta caaaccataa ggtgggaggc ggtacggtaa taaatgccgg
    13801 aagctgcaag tattcactct gctgtagttg ttcaacagta aactcgactt tcgcaccctg
    13861 agtttcggcg gtaatggtaa tgtgctgtgc ctttagcacg gcgatgttgt cttcggcttg
    13921 actgccgaaa tccagcacca gtttatccgg ggttattgcc agtaatttgc tgatcagctg
    13981 cccgccattc caactgagac gcaaaggaat tgcggctttg tgcaaatcgc gtaacacgcc
    14041 caggacggct aacggatttt gtttcaggaa ctgctcatgg taatgactca cgcggaaaaa
    14101 ctcctgactg acaaactgtc tttggtttat cggtcacagt taacaaaact taatacaaat
    14161 gcgtgaatat tttttacatg ttgttcttaa atcagccgac atacgcccag catcgatccc
    14221 gcccttgcct atacttagag cgttgatgta agcatttctt gcgtccgatt catcgaaacg
    14281 agggcctgaa catgggaatt attgcctgga ttatttttga cctgatagcc ggcattatcg
    14341 ccaagctaat catgccgggg cgtgatggtg gtggattttt cctgacctgt attctcggga
    14401 tagtcggtgc ggtggtcggc ggctggctgg cgaccatgtt tggcattggc ggctccatca
    14461 gtggttttaa tctgcacagc ttcctggtgg cggtggtggg agctattctc gttctgggca
    14521 tattccgcct cctgcgaaga gaataagatt ttcataaggc ggatagcgat acagatgccg
    14581 ctatccgctt tcacatcaga acgtatactc gacacctgct ttacgggtga aaaaaatcaa
    14641 tatagcactt cgatatccga taaagtcggt tcccggtaac aacaacagaa tcctttttta
    14701 attattgttt cgttgttttt ggtgtgattc agaaaataaa tattttagac agtagccagt
    14761 caggcgttaa aaatggggcg gatagtgagg cggttttggc tgcgcttact gaacatttag
    14821 aattgatcaa tccttctggc agattaagcc aaaatacccg ttcggcaatg cttcagttac
    14881 gcgaagagga atggtctgaa ttcttttttt ggttgctaaa ttctctggag tgtctggatt
    14941 atgtgattat taatttaact ccagaaagca aaaaaacgtt gatgagtgaa caccgtaaca
    15001 atattcaggt agcaattgat gctttatata gccaacgtcg gcgtaaatcg ccgggtgatg
    15061 aaagtgaaac acttacccgt agaaatgacg ctatcttcgg caaccacgta tggcaaacat
    15121 ttgcgcaata cttcccgtca ggacttgaaa aaccgtctgt gtagaaaaaa ccatagctat
    15181 ggtgttatct gccgacaacg ccatccggag aagccgaatg acgttgtcgg agtaagcgct
    15241 ggttaaggtg tgggttgtgc ctctttggtt gagggttgcg tcgttgctga cttaacggtc
    15301 ggacgcgtcg ccggaacatt gtcacacggt tgctctttcg ggcagatcaa atccagcatt
    15361 ttcagcgtca cgccattggt ccagccaaag ccatcctgta atggatattc gccaccgccg
    15421 ccccccgttc cggtggtgct gacatcatat ttttccacca gctttttctc ccggtcatag
    15481 gtgtgctgaa cattggtcag gaagtgccag ctaatgtcca tcgccacctc tttttgcccg
    15541 tagttttgta atccttctgt cgcgacccac tgtaacggtg cccagccatt tggcgcatcc
    15601 cattgttgcc cacttttcac cgacgtggtg ttcaggccgc cgggttgcag cagatgtgtt
    15661 ttcgtcgccg tcgccatttt gttggcgcga tctttcgctg ccgcattgac gtacagcgg
//
LOCUS       DACAOP010000100        15654 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.100, whole genome shotgun sequence.
ACCESSION   DACAOP010000100 DACAOP010000000
VERSION     DACAOP010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15654
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.100"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..318
                     /locus_tag="IT892_003598"
     CDS             <1..318
                     /locus_tag="IT892_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAP3136765.1"
                     /translation="DRPDITVRYYYKGVLWSPGYFASSCGGAPISAIRQYIEQQQTPG
                     QVENRAVYPRPEGRGFTAHRINQAKRMLVDPIISPKRSNINIHLQWVDIWLKNIVFLS
                     FIQ"
     gene            759..1553
                     /locus_tag="IT892_003599"
     CDS             759..1553
                     /locus_tag="IT892_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2686 family protein"
                     /protein_id="HAP3136766.1"
                     /translation="MTLPTTIYSFPAYSPRFSSTDKPAKLKFHQYVRATLLSNRGRDH
                     NCDGRRTVEIHKLDLSDWQAFNKLATKCNAYDGVTMNGDNSFGWNHEATLDNIHAQKY
                     NKAYAGARLTAELKYLLQDVESFEPNSKYTIHEVVLGPGYSTPDYTGQTIGYVVTLPA
                     QMPNCWSSELPTIDLYIDQLRTVTGVSNALGFIIAALLNAYSDLPHDLKIGLRSLSNS
                     AAIYSGLGFERVPQNRDIRSDRMHLTPANHPDLWTQENGEWIYLRN"
     gene            complement(1624..2073)
                     /gene="rplI"
                     /locus_tag="IT892_003600"
     CDS             complement(1624..2073)
                     /gene="rplI"
                     /locus_tag="IT892_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAP3136767.1"
                     /translation="MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNI
                     EFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADA
                     VTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE"
     gene            complement(2115..2342)
                     /gene="rpsR"
                     /locus_tag="IT892_003601"
     CDS             complement(2115..2342)
                     /gene="rpsR"
                     /locus_tag="IT892_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAP3136768.1"
                     /translation="MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRI
                     TGTRAKYQRQLARAIKRARYLSLLPYTDRHQ"
     gene            complement(2347..2661)
                     /gene="priB"
                     /locus_tag="IT892_003602"
     CDS             complement(2347..2661)
                     /gene="priB"
                     /locus_tag="IT892_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001315977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HAP3136769.1"
                     /translation="MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHR
                     QAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDS
                     GD"
     gene            complement(2668..3063)
                     /gene="rpsF"
                     /locus_tag="IT892_003603"
     CDS             complement(2668..3063)
                     /gene="rpsF"
                     /locus_tag="IT892_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAP3136770.1"
                     /translation="MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGR
                     RQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPM
                     VKAKDERRERRDDFANETADDAEAGDSEE"
     gene            3390..3665
                     /locus_tag="IT892_003604"
     CDS             3390..3665
                     /locus_tag="IT892_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HAP3136771.1"
                     /translation="MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDVQSLGVIYIN
                     HNFATESEARQALNEETDAQGATYYHVILMREPGSNGNMHASADIYR"
     gene            complement(3740..4291)
                     /locus_tag="IT892_003605"
     CDS             complement(3740..4291)
                     /locus_tag="IT892_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1440 domain-containing protein"
                     /protein_id="HAP3136772.1"
                     /translation="MAIKGLFVRTDPQRRRYGVALLVGVLSGIISAFVKWGAEVPLPP
                     RTFSGGRDEFNPPYIFLRDYLGIDPTQTVYTFSEHIINPVMVTHIIFSLVFAIGYCVV
                     AEIFPKVKLWQGILAGLIVTVAVHGIFCPALNLTPPLTQLPFDEYASEILGHIFWFWI
                     IEIMRRDLRNRITHEPDPEVAIR"
     gene            complement(4386..5072)
                     /locus_tag="IT892_003606"
     CDS             complement(4386..5072)
                     /locus_tag="IT892_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP3136773.1"
                     /translation="MQKLKQQVFEANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSG
                     VAYETMKADDMVVVDMSGRVVEGEYRPSSDTATHLELYRRYSSLGGIVHTHSTHATAW
                     AQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGKVIIETLGDAEPLHTP
                     GIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRK
                     HGPNAYYGQK"
     gene            complement(5072..5926)
                     /locus_tag="IT892_003607"
     CDS             complement(5072..5926)
                     /locus_tag="IT892_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase UlaE"
                     /protein_id="HAP3136774.1"
                     /translation="MLSKQIPLGIYEKALPAGECWLERLRLAKTLGFDFVEMSVDETD
                     ERLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKA
                     IQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYP
                     LMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPG
                     VFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMA
                     KAGMVEAA"
     gene            complement(5936..6586)
                     /gene="ulaD"
                     /locus_tag="IT892_003608"
     CDS             complement(5936..6586)
                     /gene="ulaD"
                     /locus_tag="IT892_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAP3136775.1"
                     /translation="MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGV
                     RAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVMVICCADINTAKGALDVA
                     KEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLS
                     DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG"
     gene            complement(6600..7064)
                     /gene="ulaC"
                     /locus_tag="IT892_003609"
     CDS             complement(6600..7064)
                     /gene="ulaC"
                     /locus_tag="IT892_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIA"
                     /protein_id="HAP3136776.1"
                     /translation="MKLRDSLAENKSIRLQAEAETWQDAVKIGVDLLVAADVVEPRYY
                     QAILDGVEQFGPYFVIAPGLAMPHGRPEEGVKKTGFALVTLKKPLVFNHEDNDPVDIL
                     ITMAAVDANTHQEVGIMQIVNLFEDEENFDRLRACRTEQEVLDLIDRTNAAA"
     gene            complement(7074..7379)
                     /gene="ulaB"
                     /locus_tag="IT892_003610"
     CDS             complement(7074..7379)
                     /gene="ulaB"
                     /locus_tag="IT892_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIB"
                     /protein_id="HAP3136777.1"
                     /translation="MTVRILAVCGNGQGSSMIMKMKVDQFLTQSKIDHTVNSCAVGEY
                     KSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK"
     gene            complement(7395..8642)
                     /gene="ulaA"
                     /locus_tag="IT892_003611"
                     /pseudo
     CDS             complement(7395..8642)
                     /gene="ulaA"
                     /locus_tag="IT892_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418614.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
     gene            8635..9027
                     /locus_tag="IT892_003612"
     CDS             8635..9027
                     /locus_tag="IT892_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136778.1"
                     /translation="MKPNYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRM
                     GEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLD
                     KDNFEYHYPRGFDDCFTIEPDLPFKSFL"
     gene            9135..9889
                     /gene="ulaR"
                     /locus_tag="IT892_003613"
                     /pseudo
     CDS             9135..9889
                     /gene="ulaR"
                     /locus_tag="IT892_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator UlaR"
     gene            complement(9886..10635)
                     /gene="yjfP"
                     /locus_tag="IT892_003614"
     CDS             complement(9886..10635)
                     /gene="yjfP"
                     /locus_tag="IT892_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAP3136779.1"
                     /translation="MIEIESRELADIPVLHAYPVGQKDTPLPCAIFYHGFTSSSLVYS
                     YFAVALAQAGLRVIMPDAPDHGSRFSGDAARRLNQFWQILLQSMQEFTTLRAAIAEEN
                     WLLDDRLAVGGASMGAMTALGITARHPTVKCTASMMGSGYFTSLARSLFPPLIPETAA
                     QQNEFNNIVAPLAEWEATNHLEQLGDRPLLLWHGLDDDVVPADESLRLQQALSETGRD
                     KLLTCSWQPGVRHRITPEALDAAVTFFRQHL"
     gene            10817..11146
                     /gene="bsmA"
                     /locus_tag="IT892_003615"
     CDS             10817..11146
                     /gene="bsmA"
                     /locus_tag="IT892_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313192.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm peroxide resistance protein BsmA"
                     /protein_id="HAP3136780.1"
                     /translation="MVSRKRNSVIYRFASLLLVLMLSACSALQGTPQPAPPVTDHPQE
                     IRRDQTQGLQRIGSVSTMVRGSPDDALAEIRAKAVAAKADYYVVVMVNETIVTGQWYS
                     QAILYRK"
     gene            11295..11570
                     /gene="yjfN"
                     /locus_tag="IT892_003616"
     CDS             11295..11570
                     /gene="yjfN"
                     /locus_tag="IT892_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418609.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease activator YjfN"
                     /protein_id="HAP3136781.1"
                     /translation="MKQLLASPSLQLVTYPASATAQSAEFASADCVTGLNEIGQISVS
                     NISGDPQDVERIVALKADEQGASWYRIITMYEDQQPDNWRVQAILYA"
     gene            complement(11687..13312)
                     /locus_tag="IT892_003617"
     CDS             complement(11687..13312)
                     /locus_tag="IT892_003617"
                     /EC_number="1.3.8.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418608.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HAP3136782.1"
                     /translation="MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLA
                     SIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALYTNRVHN
                     LAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPAPFQDWTTPL
                     LSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFS
                     VPQSDAHLVLAQTAGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA
                     IGWLLGQEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQ
                     PLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPF
                     VAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLS
                     EAFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLLGCGAQMLKYASPPMAQ
                     AWCQVMLDTRGGVRLSEQIQNDLLLRATGGVCV"
     gene            complement(13396..14559)
                     /locus_tag="IT892_003618"
     CDS             complement(13396..14559)
                     /locus_tag="IT892_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HAP3136783.1"
                     /translation="MLRHNVPVRRDLDQIAADNGFDFHIIDNEIYWDESRAYRFTLRQ
                     IEEQIEKPTAELHQMCLEVVDRAVKDEEILTQLAIPPLYWDVIAESWRARDPSLYGRM
                     DFAWCGNAPVKLLEYNADTPTSLYESAYFQWLWLEDARRSGIIPRDADQYNAIQERLI
                     SRFSELYSREPFYFCCCQDTDEDRSTVLYLQDCAQQAGQESRFIYIEDLGLGVGGVLT
                     DLDDNVIQRAFKLYPLEWMMRDDNGPLLRKRREQWVEPLWKSILSNKGLMPLLWRFFP
                     GHPNLLASWFEGEKSQIAAGESYVRKPLYSREGGNVTIFDGQNNVVDHADGDYADEPM
                     IYQAFQPLPRFGDSYTLIGSWIVDDEACGMGIREDNTLITKDTSRFVPHYIAG"
     gene            complement(14562..15200)
                     /locus_tag="IT892_003619"
     CDS             complement(14562..15200)
                     /locus_tag="IT892_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 domain-containing protein"
                     /protein_id="HAP3136784.1"
                     /translation="MARKRKSRNNSKIGHGAISRIGRPNNPFEPRRNRYAQKYLTLAL
                     MGGAAFFVLKGCGDSGDVDNDGDGTFYSTVQDCIDDGNNSDICAHGWNNAKAAFYADV
                     PKNMTQQNCQSKYENCYYDNVEQSWIPVVSGFLLSRVIRKDRDEPFVYNSGGSSFASR
                     PVWRSTSGDYSWRSGSGKKESYSSGGFTTKKASTVSRGGYGRSSSARGHWGG"
     gene            complement(15210..15608)
                     /locus_tag="IT892_003620"
     CDS             complement(15210..15608)
                     /locus_tag="IT892_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF350 domain-containing protein"
                     /protein_id="HAP3136785.1"
                     /translation="MHILDSLLAFSAYFFIGVAMVIIFLFIYSKITPHNEWQLIKNNN
                     TAASLAFSGTLLGYVIPLSSAAINAVSIPDYFAWGGIALVIQLLVFAGVRLYMPALSE
                     KIINHNTAAGMFMGTAALAGGIFNAACMTW"
BASE COUNT         4055 a         4196 c         3718 g         3685 t
ORIGIN      
        1 gatcgaccag atattacagt caggtattac tacaaaggcg ttttgtggag tcctggctat
       61 tttgccagta gctgcggagg tgcgccaata tccgccatcc gtcaatacat tgaacaacag
      121 caaacacctg gtcaggtgga aaaccgcgcc gtatatcccc gccctgaagg acggggtttt
      181 acggcgcacc ggataaacca ggccaagcgt atgctggttg atccaataat atcccccaag
      241 cgcagcaata ttaatattca cctgcaatgg gtcgatatct ggcttaaaaa tattgtgttt
      301 ctttccttca tccaataagg attccattaa ctgcaagtgc gcatggttaa tttctaagag
      361 acgctgtgat tttgcataat gcacaccttt actttgattt tcactatgca caatttttaa
      421 aaactacggg ttagcaatat aataatccca tgtaaaatca ataattttct caatggcttt
      481 ttgtggctgg ttaaccagat gattaacaaa cgcaccgata ccaacagcgt agaataatta
      541 cataccgcac aacaagaatg tatggtggaa ggcgtggaag tcattttctc cccgggggca
      601 tcgttatatc cataatgagc gatttttgat attaatatct ttcaccatcc gctattttca
      661 ctacttcaga aaacaaacat atttttatta atatcgattc tttttctgtg aacattcagc
      721 tgcgatattt ataaaaacat taaacaggta acattacaat gacattacca acgactattt
      781 attcatttcc tgcatattca ccccgttttt cgtccaccga caaaccagca aaattaaaat
      841 ttcatcaata cgtacgcgct acattactgt caaatcgtgg aagagatcat aattgcgatg
      901 gcagacgtac tgttgagatc cacaaactag atctctctga ctggcaagca ttcaataagt
      961 tagcaacgaa gtgtaatgct tacgatggag taacaatgaa tggtgataat tcttttggat
     1021 ggaaccatga agctacatta gataatattc acgcccagaa atacaataaa gcttacgcgg
     1081 gtgcgaggtt aaccgcagaa ctgaaatatt tattgcaaga tgtcgaatcc ttcgaaccca
     1141 acagtaaata cacaatacac gaggttgttt tgggacctgg ttatagtact ccagactata
     1201 ccggccaaac gataggatac gttgtaaccc ttcctgccca aatgcctaat tgctggtcat
     1261 ctgaactacc aacaatcgat ctttatatcg accaacttcg cactgttaca ggcgtttcta
     1321 atgccctcgg attcatcatt gctgcattgc taaacgcgta ttctgattta ccccatgatt
     1381 tgaaaattgg tctacgttcc ttatcaaatt cagcagcaat ctactcgggt ttaggtttcg
     1441 agcgagtgcc gcagaaccga gacataagga gtgatcgtat gcatctaacg ccagcaaacc
     1501 atcctgactt atggacacaa gagaatggtg aatggatcta cttgcgaaac taatacctga
     1561 cgaaaaatag aaagcaaaac gccgaccaat ggtcggcgtt tttacgtctc gttgaataac
     1621 gaattattca gctactacgt ttacgatcac tttcgcgaat acttcgctgt gaacctggaa
     1681 gctcacttcg tgttcgccag tggtacgcag aacgccgttc ggcagacgaa cttcgctctt
     1741 agccacttca acgccagctg cagttacagc gtcagcgatg tcgcgagtac cgatggaacc
     1801 gaacagttta ccttcgtcgc cagctttaga cgcgatggta acagtttcca gtgcattgat
     1861 tttctcagcg cgagcattag cagctgccag aacttcagcc agtttagctt ccagttcagc
     1921 gcgacgtgct tcgaagaatt caatgttttt cttggtagct ggaacagctt taccctgcgg
     1981 taccaggaag ttacgagcat agcccgcttt aacgtttacc tgatcaccca ggctacccag
     2041 gtttgctact ttatcaagca gaataacttg cattacctta tcctctcaaa gtcgtattaa
     2101 tggaccgtga ccgattactg atggcgatca gtgtacggca gcagggacag gtagcgagcg
     2161 cgtttgatag cgcgagccag ctgacgctgg tattttgcac gggtaccggt gatacggctt
     2221 gggacaatct taccgctttc ggtgatgtag tttttcagcg tagcgatatc tttatagtcg
     2281 atctcttgaa cgccttccgc ggtgaaacgg cagaacttgc gacgacggaa ataacgtgcc
     2341 atatggctag tctccagaat ctatcaattc aatctgctcg gcatgcaaaa ccattttgct
     2401 cagtccgttc tttgccttgt ggcatgaaat gaacccctga acggttatgc gactgccgac
     2461 cgttatactg tgagtaatgg cctggttttc gtgtccgcta acaataacgg gcatttggca
     2521 ccacgcctgc cggtgaaaac cggcttcctc ctgcacagaa cgatgctcaa gcacgaactg
     2581 gcagtgagga attcctgatg gactgacctt tcgaagggga gtcctgcaca cggtgccgga
     2641 caacaccaga cggttggtca tcagaaatta ctcttcagaa tccccagctt cagcatcatc
     2701 agcggtttcg tttgcgaaat catcgcgacg ctcacggcgc tcgtctttcg ctttaaccat
     2761 cggagatgct tcggtaacag cgtgcttggt acgcataacc atgctgcgga taacggcatc
     2821 gttgaagcgg aaggtagttt ccagctcatc gatcacttcc tgcggagctt caacgttcat
     2881 cagaacgtag tgtgctttgt gcagtttgtt gatcgggtaa gccagctgac ggcggcccca
     2941 gtcttccaga cggtggatct tgccttctgc accagtgatg gcagcagtgt agcgctcgat
     3001 catgcccgga acctgttcgc tctggtcagg atggaccata aaaacgattt cgtaatgacg
     3061 catcgaattg ctccttacgg attattcagc ctcctgtctg ggtcagccga atcccgggga
     3121 ggcaaggaac gtgttaaagg tcggctgaaa aatgacgcgt tatagtactt gtatgccccg
     3181 ctaaactcaa gggcagccga caaataaatc tcatctttcg ctcaaaagaa ctaactcgct
     3241 gatttgaagt tcatcacatt ccgtcacagt gttttttcga acaactgcat cagaaatggt
     3301 caccatcaac ttctttatca ttgattaaaa ttaaatcaga agatcatcac agaggagagc
     3361 acacaaagtc agccgtcgag gaggtatcta tgttcagtcg agttttagcc cttctggctg
     3421 tgcttttgct aagtgcaaat acatgggcag ccattgaaat taataaccac caggccagaa
     3481 acatggatga tgtgcaaagc ttaggcgtga tttatatcaa tcataatttc gccactgaaa
     3541 gcgaagcacg tcaggcatta aatgaagaga cagatgcgca gggcgcaacg tactaccacg
     3601 taattctgat gcgggaaccg gggagtaacg gcaatatgca cgccagcgcg gatatttatc
     3661 gctagcacca ggtataacca acgaaacatt gccatagttt gctttgcccc cttcgcaggg
     3721 ggctttttta tacggttatt caccgaattg cgacttccgg atctggctca tgagtaatgc
     3781 gattacgtaa gtcgcggcgc ataatctcta ttatccagaa ccagaaaata tgccccagga
     3841 tttcagacgc atattcgtca aaaggcaatt gagtgagcgg cggcgttaaa ttcagcgccg
     3901 ggcaaaatat accgtggact gccactgtca caataagccc tgctaatatc ccctgccata
     3961 atttcacttt cgggaaaatt tccgcgacaa cacaataccc tatcgcaaaa accagtgaga
     4021 agatgatatg cgtcaccatc accgggttga taatatgttc cgagaatgtg tacacagttt
     4081 gggttgggtc gatacctaaa taatctcgta gaaagatata cggcgggtta aattcatcgc
     4141 gaccaccgga aaatgtgcgc ggtggcaagg ggacttccgc tccccattta acaaatgctg
     4201 aaataattcc tgaaagtaca cccacaagta acgcaacgcc atagcggcga cgctgcggat
     4261 ccgttctgac aaacaatcct ttgatagcca taaagcacct gatgttgatg attttattaa
     4321 ctggagaggc cccggaatca gaccaattac atcccgcagg aggtaataat tccggggcgc
     4381 actgcttact tctgcccgta ataggcgtta ggaccgtgct tacgcatgaa gtgtttattc
     4441 atgaggaagc tgtcgatgtg attcagttgt gggttaatac tgcgcgcaat ccacgccatt
     4501 ttcgccactt cttccatcac taccgcgtta tgcaccgcat cgtgagcatc tttcccccag
     4561 gcgaacggcc cgtgctgata caccacaatc cccggcgtat gcagcggctc ggcgtcaccc
     4621 agcgtttcga taatcacttt gccggtgttc agttcatact cgccctgcac ctcttcttcg
     4681 cttaatccgc gcgtacacgg gatgtcgcca aagaagtagt cggcgtgcgt agtgcctaac
     4741 gccgggatcg ccagccccgc ctgcgcccat gcggtagcat gagtggagtg ggtatggaca
     4801 atgccgccaa gcgacgagta acgacggtag agttcgagat gcgtcgcggt gtcggaagat
     4861 gggcgatact ccccttccac caccctgccg ctcatatcaa ccaccaccat atcgtctgct
     4921 ttcatggttt cgtaggcaac gccgctgggc ttgatcacca ccagcccgcg ttcgcggtcg
     4981 atggcgctga cattgcccca ggtaaaggtc accagcccgt agcgcggcag atccatgttg
     5041 gcttcaaata cctgctgttt cagcttttgc attatgccgc ctccaccatg ccagctttgg
     5101 ccatgcgcgc tttcacccaa tcacgcgctt tcgccacttc cgccgccggg tcttccgccg
     5161 tttcgctcca catctcaatc aggtacggcc cgcaatagcc actctgcttg agcgtttcga
     5221 agcaacgttc gaaatccacc acaccttcgc caaacggcac gtttttgaag acgcccggtt
     5281 tggtgtcttt cacatgcacc gcgacgatat gcccgattcc ggcctgcaac tccatctgta
     5341 cgtcgttgtc ccacgccgac aggttgccga tatccgggta gagctggaac cacgggttgt
     5401 tgagatagtg cgcgtaaccc agcgccttgc tgatggagtt catcaacgga taatccatga
     5461 tctccatcgc cagcgtcacc tgcgcgcggc tcgccatctc aacgctctct ttcaggccgt
     5521 cacggaaacg acgacgcgtt tcgttattgg cttcctgata gtaaacgtca taacccgcca
     5581 gctggatcac gcgaatgcca acgtcctggg cgaactggat ggctttacgc ataatctcca
     5641 gcccctgcgc ccgcaccgcg tcatcttcgc tgcccaacgg aaaacgacga tgggcagaaa
     5701 ggcacatgga cggcacacgc acgccggttt caacaatcgc attcaccagc gccagacgct
     5761 gctcgcggct ccagtcgagg cgcgacaggc gctcgtccgt ttcatccacc gacatctcga
     5821 caaaatcgaa gcccaacgtt tttgccagtc gcaggcgttc cagccagcac tccccggcgg
     5881 ggagcgcttt ttcatagatg ccaagcggga tttgtttgga caacatatcc gctccttagc
     5941 cccacagttc ggcgatggaa cgtttgaact gacgcgcggc ttcaaccgga gaagcggcat
     6001 cacggatgct gcgaccggcg ataaacacat gaattggaat gcctttgaac agcggcagat
     6061 cttccagcgc caggccaccg gtgacggtga ctttgaagcc catatcggaa agacgtttga
     6121 tcgcagtgat atcggcttca ccccacgcca cgccagcggc ctgcgcgtca cggctgcggt
     6181 gataaaccac ctgctgaatg cctgcgtcgc gccactgttg cgcctgttcc caggtccagt
     6241 aaccggtcag ttcgatctgc acgtcgccgt taaactcttt tgccacgtcc agagcgcctt
     6301 tggcggtgtt gatatccgca cagcaaatta ccatcaccca gtcagcgttg gcttcgaagc
     6361 acatacgaga gaggattttg cccgcatcgg caattttggc atctgccagc acgattttgt
     6421 gcgggtaaag cgctttcagg tcacgaaccg cacgcacgcc ttcgcccaca cacagaatgg
     6481 tgcccacttc gataatgtcg acttcttcgg caatcaggcg agtggtttcg taggcgctgt
     6541 ccatagtctg gttgtccagc gcgacttgca acatgggtaa tgacatcttc aattccttct
     6601 taagctgccg cgttggtgcg gtcaatgaga tccagtactt cctgctcggt acggcaggca
     6661 cgtaaacggt cgaaattctc ttcatcttca aacaggttga cgatctgcat gatgcccact
     6721 tcctggtgag tgttggcatc gaccgccgcc atggtgatga ggatatccac cgggtcgtta
     6781 tcttcgtggt taaacaccag aggctttttc agcgtcacca gcgcaaaacc ggttttctta
     6841 acaccctctt ccggccgccc gtgcggcatc gccagccccg gagcgataac gaaataaggg
     6901 ccaaactgtt ccacgccatc cagaatcgcc tggtaatagc gcggctcgac aacgtccgcc
     6961 gccaccagca gatcgacgcc gattttcacc gcgtcctgcc aggtttcagc ttcagcctgc
     7021 aggcggatgg atttattttc agccagcgaa tcacgtaatt tcatggcgcg tccttacttc
     7081 acatcctgcg ggaaatgttc tttgatcact tccagcagtt tcgggccaaa atcagcagga
     7141 gagagcatgt tgcgcacgcc aaccacgtat ttgttgccgg taacggtgat ttcgcccgca
     7201 atgtgcgtag aagcgatgat gatatccgcg ccgctcaact cacttttgta ttcgccaacc
     7261 gcgcagctat ttaccgtgtg gtcaatcttt gattgggtta aaaactggtc cactttcatt
     7321 ttcatgatca tggaactgcc ttgtccgttg ccacacacag ccagaatacg tacggtcata
     7381 atcaaaactc cttattaagc agactgttct gccagttgtt tttctgcatc ttcttcagcg
     7441 cgtagctcac gcccggcgaa gaacatataa gccagtgaaa taacaatgat gacggccata
     7501 aaggcgatac cgatggagaa gaagccctgc atcatcggcg gtgccagaat cgaccagtcc
     7561 gccataccca tccaggcact cataccggta agtttcaccg cccagacgca accaaagatt
     7621 tcgatcatcc ccatcaccag acaaatcttc agcgccgcac gccagccgcc gaagtggtta
     7681 gcgaatacgc cgatggtggc gttagagaag aacatcggga taaagcctgg aataatcagg
     7741 atcgaggagc cacaggcgac caggatgcca accgcaatca gctgaccgat agtaccccac
     7801 ataaagcccc agaccacggc gttcggcgcg aagctataga tagccgcaca gtcaatcgcc
     7861 agaaccgcac ctgggatcag gcgctgagag ataccgttaa acgcttcaga gagttccgcc
     7921 acaaacatgc gcacaccctg agtgatgatg aagatcgcca ctgcaaagga gaaaccggtt
     7981 tgcaggatgt agaccgtcca gtgcactttg cctgccatcg cctgcacggt gtcgataccg
     8041 aaggagagca gaatggcacc aaagaagatg gtcatcacaa tcgccgtgga gacgatgttg
     8101 tcatggaaaa tgttcagcca gccaggcaat ttgaggtctt caacgctctc ctcttttttg
     8161 ccgaggaacg gcgcaacttt ataagcaatc catgccgcaa actgttgctg gtgaccgata
     8221 gagaagccgc aaccatccgt aacgatttgt gtcggcttgt acatcatgtt ggaggtaata
     8281 ccccagtaga gcgaaaccat gattgcagtg caaataatgg tcgtccacat ggagtagccg
     8341 aagataaaca gcgtaacggc aatcagcccg gcctgctgga acatgatgtg gccggtcaac
     8401 atgatggtac gaataccggt aatgcgacgc agcagcacgt aacagatgtt cagtgccagc
     8461 gctaataaca ccgcgtaacc tacccagcta taggcatcgc ccatgcggtc gatggttgcc
     8521 atcatcgaag cgtaagtatc agaaattgcg ccgttaatgc cgtagacttc ggacattttc
     8581 gccaccaccg gtttgaaggt gctggtgagg atgccggacc ctgcctgcaa caacatgaaa
     8641 ccaaactact ctaactatta tgcgaagcac ggtaacgaac atcagatcga cgtggcttta
     8701 ggttcatacg gcgaaaaccc gcgcggtatc accgacaaaa tgaccagcgc cgatatgctg
     8761 cgtatgggtg aagccctgaa tgcgaaagtg gttatcccgt tccaccacga tatctggtca
     8821 aacttccagg ccgatccgca agagatccgc gtgctgtggg agatgaaaaa agatcgtctg
     8881 aagtatggct tcaagccgtt tatctggcag gttggcggca aatttacctg gccgctggat
     8941 aaagacaact tcgagtacca ctatccgcgc ggtttcgatg attgcttcac tattgaaccg
     9001 gatctgccgt tcaagtcatt cctgtaatct gtcgtttata ccggatagcg tggagtagtt
     9061 cgcgctatcc ggcgtagtat ttcctggcta tttcaaatat catctaaaaa aatcaaattt
     9121 tatcggaata gctcatgact gaagcacaaa gacatcaaat cctcctggaa atgctcgcac
     9181 aattgggctt tgtgaccgtt gagaaagtcg ttgagcgtct gggaatttcg cctgctactg
     9241 cgcgacgcga tatcaataaa cttgacgaaa gcggcaactg aaaaaagtgc gcaatggcgc
     9301 agaagctatt acccaacagc gcccgcgctg gacgccgatg aatctgcatc aggcgcagaa
     9361 tcacgatgaa aaagtacgta tcgctaaagc agcctcgcag ctggttaatc cgggcgaaag
     9421 cgtagtcatc aactgcggct ccaccgcgtt tctgcttggg cgggaaatgt gtggcaagcc
     9481 agtgcaaatc atcactaatt atctaccgct ggcaaattac ctgatcgatc aagaacatga
     9541 cagcgtgatc attatgggcg gacagtacaa caaaagtcag tccatcactt taagcccgca
     9601 aggcagcgaa aacagtctct atgccgggca ctggatgttt accagcggca aaggactgac
     9661 agcagaaggg ttgtataaaa ccgatatgct gacggcaatg gcagagcaga agatgctgag
     9721 cgtagtagga aaactggtgg tgctggttga tagcagtaag attggcgaac gcgcgggaat
     9781 gctttttagc cgtgccgatc aaatcgatat gcttatcacc ggcaaaaatg ctaacccgga
     9841 aatcctgcaa caactggaag cgcaaggggt cagcattctg cgtgtttaaa gatgctggcg
     9901 gaaaaatgtc acggcagcat ctaacgcctc aggcgtaatg cggtgacgca cgcctggttg
     9961 ccatgaacag gttagcagtt tatcccgtcc cgtctcgctt aaggcctgct gcaaacgtag
    10021 tgattcatcg gcaggcacaa cgtcatcgtc gaggccatgc cacagcagta gaggtctgtc
    10081 accaagttgt tccaggtggt ttgtcgcttc ccactctgcc agcggcgcga caatgttatt
    10141 gaattcattc tgctgtgctg ccgtttcagg tatcagaggt ggaaacagtg aacgggcgag
    10201 cgatgtaaaa tagcccgatc ccatcatgct ggcggtacat ttcaccgtgg ggtggcgagc
    10261 ggtaatcccc agtgccgtca tcgcgcccat cgacgcgcca ccgactgcca gacggtcatc
    10321 aagcagccag ttttcttcgg ctattgccgc acgtaacgta gtgaattcct gcatactttg
    10381 tagcaagatt tgccagaatt gatttaaccg ccgcgctgcg tcaccactaa aacggctacc
    10441 gtgatcgggc gcatccggca tgatcacccg caaaccagcc tgcgccagcg caacggcaaa
    10501 atagctatac accaggctgg acgaagtaaa gccgtgataa aaaatcgcgc acggtaacgg
    10561 ggtatctttt tgcccgacag gataagcatg aagaacggga atatctgcca actcgcgtga
    10621 ttctatttca atcatctgtc tctccttttt gtctggtatg acatgaagaa atccttagca
    10681 caagtttctg ctggcggtat tagttcataa tgttgagatg tgggttacgc tttcgtcacg
    10741 ttttcattcg aaaatcgcgt accaggtaac aattcgggaa cattccccca aagttaaatt
    10801 aataaggcac tacactatgg ttagcaggaa acgtaatagc gttatttacc ggtttgccag
    10861 tttattattg gtgttgatgt taagtgcctg tagcgcactg caaggtacgc cacaaccagc
    10921 accgccagta accgaccatc cgcaagagat tcgccgcgac cagacgcaag ggttacagcg
    10981 aataggtagc gtaagcacga tggttcgggg ttctccggat gacgcattag cagaaatcag
    11041 agcgaaagct gtcgctgcaa aagctgatta ttacgttgtc gtcatggtga acgaaaccat
    11101 cgtgacagga cagtggtatt cacaagccat tttgtaccgt aaataaatca gacaacttac
    11161 atagtcagct ttacattgct ttgcgtccct atgcgtttac ctgtgcacaa taaattaccg
    11221 gctggaagct cgggcgttta ttaccgcgat ggaatgccct gcaacatgtg gggaaacgaa
    11281 aaatggagct gacgatgaaa caattacttg cctcaccctc gctgcaatta gtgacttatc
    11341 ctgcgagcgc cacggcacag tctgcagaat tcgccagtgc tgactgcgtg acgggcctga
    11401 atgaaatagg tcagatctca gttagcaata tttcagggga tccgcaggac gtggaacgta
    11461 tcgtggcgtt aaaggccgat gaacaaggtg cgtcatggta ccgcattatt accatgtacg
    11521 aagaccagca gcctgataac tggcgcgtac aggcgatact gtatgcatga gtgtcatcta
    11581 cagcaaatga acaatgccgg atgcggcgcg agcgccttgt ccggcctaca attttcacat
    11641 atttcattta gttaatcgaa accagcgtcg catcagtcgt atacgcttac acacacactc
    11701 cccccgtcgc ccgcagcaat aaatcattct ggatctgctc tgacaaccgt acgccgccgc
    11761 gcgtatctaa catcacctga caccacgcct gcgccattgg cggagaagca tatttcaaca
    11821 tttgcgcacc gcagcccagc aggaatagct gatgagtaat ctctcgcccc agttcttcag
    11881 ctggcttacg cagctgctgc tgtaaacgac gaaccgcgcg atcaaaatag cgatcctgcc
    11941 ctttcacttc cacaaatgct tccgacaata agtcgtatac gcccgcttgc ttattgagaa
    12001 cgcgcaacac atccaggcac ataatattgc cggaaccttc ccaaatactg tttaccggca
    12061 tctcccggta aagccgcggc agctcgctct cctcgcaata accaatgccg cccagcacct
    12121 ccatcgcttc ggccacaaac ggcatacctc ttttgcagat cacaaatttt gccgcaggcg
    12181 taaataaacg cgcccacagg gcttctttgg catcggcacg ccggtcccac gctcgcgcaa
    12241 gacgaaacag caacgccgtt tgcccttcaa gctgaagtgc catgcgactt aagacatgac
    12301 gcataagggg ctgttggatc aatggattac caaaaacatg gcgttgatgt gcatgataaa
    12361 tcgccagcga aaatgcacgg cgcatcatgg catggctacc cagggcgcaa tcaaaacgcg
    12421 tcatcccacc cattttcagg atcagacgaa ttccttcccc ttcctgcccc aacaaccaac
    12481 caatggcatc ctgaaactcc acttcgcaac tggcgttaga gcgattaccc agcttatctt
    12541 tcagccgctc gaggcgaatc gcgttgcgtt gcccgtcagg caaaaagcgc ggcacaaaaa
    12601 agcaggacag accacccgcg gtctgcgcca gcaccagatg cgcatcgctt tgcggaaccg
    12661 agaaaaacca tttatgcccc accagccgat aagagccatc ttccagacgc tctgcacggg
    12721 tggtgttgct cataacatcg gaaccgccct gcttttccgt cattcccatg ccaatcaaca
    12781 aaccgcgttt ttgcccacct ggcaataagt gagaatcgta gcgatcgctc aatagcggcg
    12841 tggtccagtc ctgaaacggc gcgggtaaca tctgtaacaa caatggcgtg gcggcaaagg
    12901 tcatggttat cggacataac gaccctgcct caacctgcgc atgtaacata aaacgcgccg
    12961 cgcgcgccac aaatgcgccg gagcgagcgt cttcttccca ggcaagattg tgcacccgat
    13021 tggtatatag cgcctgcatc agcaggtgcc aggcggggtg aaaacgcaca tcgtccagac
    13081 ggcgtccttg cgcatcgtag cgcaataatt caggcggatt cacattcgcc agccgcccca
    13141 gttcaaggga ttcagccgtt cctaactgct gaccaatact ggctagaaaa tcgctatccc
    13201 agccagcacc ttcacgcgtt accgcttcgc agagcgcgcc atcagacagg tataagttgc
    13261 tgttatttaa tggtataggt tgattaaaaa cggtgtgagt ttgccagtgc actgagtctc
    13321 cctccatcaa tggcagtcac cattagtatg gtcactgcca tggattcatg acagaaagag
    13381 attgctaaaa cattcttatc cagcaatgta atgcggaacg aaacgtgagg tgtctttggt
    13441 gatcagtgtg ttatcttcac ggatccccat tccgcacgct tcatcatcga caatccagct
    13501 accgatgagt gtgtagctat cgccaaaccg cggcagaggt tgaaacgcct ggtagatcat
    13561 cggttcatcg gcgtaatcac catcagcgtg gtcaacgacg ttattctggc cgtcgaaaat
    13621 ggtgacattt ccgccttcgc gcgagtagag cggtttacgc acatagcttt cgccagcggc
    13681 aatctgcgat ttttcaccct caaaccagga tgcaagaagg ttaggatgac cagggaagaa
    13741 gcgccaaagc agcggcatta gccctttatt actcaagata cttttccata acggctccac
    13801 ccattgctcg cgacgcttgc gcagcagcgg accgttatcg tcacgcatca tccactccag
    13861 cggatacagc ttaaatgcac gctggatgac attatcatca agatcggtca gtacgccgcc
    13921 gacgcccaaa ccgagatctt caatgtagat aaaccgcgac tcctgccctg cctgctgggc
    13981 gcagtcctgc aagtacagca cggtactcct gtcttcatcg gtgtcctgac agcagcaaaa
    14041 ataaaacggt tcccgactgt aaagctcgct aaagcgtgaa atcaggcgtt cctgaatagc
    14101 attgtactga tcggcatcac gcggaataat gccgctgcgc cgggcatcct ccagccacag
    14161 ccactggaaa taagccgact cgtacaatga agttggcgta tcggcgttgt actccagcag
    14221 cttcaccggc gcattgccac accaggcaaa atccatccgt ccatacagcg aaggatcgcg
    14281 ggcgcgccag ctttcagcga tcacatccca gtacaacggc gggatcgcca gttgcgtcag
    14341 gatctcttca tcttttaccg cgcgatccac cacctcaagg cacatctgat gcagttccgc
    14401 agtcggtttt tcgatctgct cttcaatctg gcgcagagta aaacggtaag cccgactctc
    14461 atcccaatag atttcattgt cgatgatatg aaagtcgaaa ccgttgtcag cggcgatctg
    14521 gtccagatcc cgtcgcacag gaacgttgtg tctcagcatg attagcctcc ccaatgccca
    14581 cgggcgctgg aagaacgacc atagccgccg cgagaaacgg tagacgcttt tttggtggta
    14641 aagccgcccg aagagtaaga ctcttttttg ccagaaccgg agcgccaaga gtaatcacca
    14701 gaagtgctgc gccagactgg gcgcgaagca aaagaggaac cgccgctgtt ataaacaaac
    14761 ggctcatcgc gatctttacg aataacccgg cttaacaaaa atccagaaac gaccgggatc
    14821 caactctgtt caacgttgtc gtagtaacaa ttttcatact tagactgaca attctgctga
    14881 gtcatattct tcggaacatc ggcataaaac gccgctttgg cgttgttcca gccatgagca
    14941 cagatatctg aattattacc gtcatcaata caatcctgca cagtcgagta aaacgttccg
    15001 tcgccgtcgt tatcgacatc gccactatcg ccacaacctt tcaatacgaa aaaagcggca
    15061 ccgcccatta gcgccaacgt taagtatttt tgtgcgtaac gattgcgacg cggttcaaaa
    15121 ggattattcg gtctaccaat gcgactgatc gctccgtgac caattttact gttatttctt
    15181 gatttgcgtt ttctggccat gatcgtccat taccatgtca tacaagctgc gttaaaaata
    15241 ccgccagcca gtgcggcggt tcccataaac attcctgctg cggtattgtg attaataatt
    15301 ttttcgctta atgcgggcat ataaagtctg acgccagcaa aaacgagtaa ctgaatcacc
    15361 agtgcgatcc cgccccaggc gaaatagtct ggaatactca ccgcattgat tgccgcactg
    15421 gataatggga taacgtaacc taacaatgta ccactgaacg ccagtgacgc cgcggtatta
    15481 ttgtttttga ttaactgcca ttcgttgtgc ggtgtaattt tagaatagat aaaaagaaaa
    15541 ataatcacca tagccacgcc aataaagaaa taggcgctaa aggcaagaag tgaatccagt
    15601 atatgcattg taaacgtcct tgtaattaac caataatatg aagtgatgtc agcg
//
LOCUS       DACAOP010000101        15170 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.101, whole genome shotgun sequence.
ACCESSION   DACAOP010000101 DACAOP010000000
VERSION     DACAOP010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15170
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.101"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            10..2055
                     /gene="glgB"
                     /locus_tag="IT892_003621"
     CDS             10..2055
                     /gene="glgB"
                     /locus_tag="IT892_003621"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching enzyme"
                     /protein_id="HAP3136786.1"
                     /translation="MIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQ
                     QNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARR
                     VSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYA
                     FEAQMRPETASLICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSY
                     RELADQLVPYAKWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFID
                     AAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRRE
                     VSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFL
                     RNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDP
                     VYRQYHHDKLTFGILYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYG
                     WMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHH
                     KAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQ
                     PGKWREILNTDSMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE"
     gene            2052..4025
                     /gene="glgX"
                     /locus_tag="IT892_003622"
     CDS             2052..4025
                     /gene="glgX"
                     /locus_tag="IT892_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HAP3136787.1"
                     /translation="MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQE
                     HRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDG
                     EFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKG
                     LTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNY
                     WGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPL
                     FSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFR
                     FDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEW
                     NDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDC
                     VCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGSLDLVERRRDSIHALLTTLLLSQG
                     TPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVE
                     NRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPA
                     GEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR"
     gene            4043..5338
                     /gene="glgC"
                     /locus_tag="IT892_003623"
     CDS             4043..5338
                     /gene="glgC"
                     /locus_tag="IT892_003623"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HAP3136788.1"
                     /translation="MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPA
                     VHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLL
                     PAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
                     ARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVF
                     DADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRD
                     VGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLV
                     SGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPE
                     GMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER"
     gene            5338..6771
                     /gene="glgA"
                     /locus_tag="IT892_003624"
     CDS             5338..6771
                     /gene="glgA"
                     /locus_tag="IT892_003624"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HAP3136789.1"
                     /translation="MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAF
                     PDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFA
                     YTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
                     HNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYARE
                     ITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAEN
                     KRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVL
                     QEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTL
                     PLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRF
                     VQRQAMAMDFSWQVAAKSYRELYYRLK"
     gene            6790..9237
                     /gene="glgP"
                     /locus_tag="IT892_003625"
     CDS             6790..9237
                     /gene="glgP"
                     /locus_tag="IT892_003625"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen phosphorylase"
                     /protein_id="HAP3136790.1"
                     /translation="MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNA
                     TLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGAL
                     EAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
                     VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQ
                     IIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
                     SGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRL
                     LIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYF
                     LKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLF
                     ADFAKIFPGRFTNVTNGVTPRRWLAVANPSLSAVLDEHLGRNWRTDLSLLNELQQHCD
                     FPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVI
                     TRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKV
                     VFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEML
                     DHVGADNIFIFGNTAEKVEELRRQGYKPREYYEKDEELHQVLTQIGSGVFSPEDPGRY
                     RDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDR
                     TIKEYADHIWHIDPVRL"
     gene            9363..9584
                     /locus_tag="IT892_003626"
                     /pseudo
     CDS             9363..9584
                     /locus_tag="IT892_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312299.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
     gene            complement(9853..11358)
                     /gene="glpD"
                     /locus_tag="IT892_003627"
     CDS             complement(9853..11358)
                     /gene="glpD"
                     /locus_tag="IT892_003627"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HAP3136791.1"
                     /translation="METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA
                     SSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR
                     IGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVV
                     RKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGM
                     HLPSPYGIRLIKGSHIVVPRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYK
                     GDPKAVKIEESEINYLLNVYNTHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDY
                     TLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIE
                     GDRDDYAARLRRRYPFLTESLARHYARTYGSNSELLLGNAGTVSDLGEDFGHEFYEAE
                     LKYLVDHEWVRRADDALWRRTKQGMWLNADQQSRVSQWLVEYTQQRLSLAS"
     gene            11548..11874
                     /gene="glpE"
                     /locus_tag="IT892_003628"
     CDS             11548..11874
                     /gene="glpE"
                     /locus_tag="IT892_003628"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase GlpE"
                     /protein_id="HAP3136792.1"
                     /translation="MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAVQAFHLT
                     NDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPA
                     EVAYGA"
     gene            11919..12749
                     /gene="glpG"
                     /locus_tag="IT892_003629"
     CDS             11919..12749
                     /gene="glpG"
                     /locus_tag="IT892_003629"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease
                     GlpG"
                     /protein_id="HAP3136793.1"
                     /translation="MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQ
                     AERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMI
                     VCVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
                     LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERD
                     PQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
                     "
     gene            12766..13524
                     /locus_tag="IT892_003630"
     CDS             12766..13524
                     /locus_tag="IT892_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family transcriptional regulator"
                     /protein_id="HAP3136794.1"
                     /translation="MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELA
                     EQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQIPNGSTLFIDIGTT
                     PEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
                     SQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVN
                     MGSISMVDAVYTDAPPPVSVMQVLTDHHIQLELC"
     gene            complement(13506..15104)
                     /locus_tag="IT892_003631"
     CDS             complement(13506..15104)
                     /locus_tag="IT892_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-dependent transcriptional regulator"
                     /protein_id="HAP3136795.1"
                     /translation="MRKTVAFGFVGTVLDYAGRGSQRWSKWRPTLCLCQQESLVIDRL
                     ELLHDARSRSLFETLKRDIASVSPETEVVSVEIELHNPWDFEEVYACLHDFARGYEFQ
                     PEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQSSPPRKKEQPRGPGEVTIIDLD
                     LSRYNAIASRFAEERQQTLDFLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTG
                     AGKSFLARRIFELKQARHQFSGAFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREG
                     LLRSANGGMLFLDEIGELGADEQAMLLKAIEEKTFYPFGSDRQVSSDFQLIAGTVRDL
                     RQLVAEGKFREDLYARINLWTFTLPGLRQRQEDIEPNLDYEVERHASLTGDSVRFNTE
                     ARRAWLAFATSPQATWRGNFRELSASVTRMATFATSGRITLDVVEDEINRLRYNWQES
                     RPSALTALLGAEAENIDLFDRMQLEHVIAICRQAKSLSAAGRQLFDVSRQGKASVNDA
                     DRLRKYLARFGLTWEAVQDQHSSS"
BASE COUNT         3455 a         3882 c         4161 g         3672 t
ORIGIN      
        1 gatgtgtggg tgattgaacc gaaaaccggg cgcaaactcg caaaactgga gtgtctcgac
       61 tcacggggat tctttagcgg cgtcattccg cgacgtaaga attttttccg ctatcagttg
      121 gctgttgtct ggcatggtca gcaaaacctg attgatgatc cttaccgttt tggtccgcta
      181 atccaggaaa tggatgcctg gctattatct gaaggtactc acctgcgccc gtatgaaacc
      241 ttaggcgcgc atgcagatac tatggatggc gtcacaggta cgcgtttctc tgtctgggct
      301 ccaaacgccc gtcgggtctc ggtggttggg caattcaact actgggacgg tcgccgtcac
      361 ccgatgcgcc tgcgtaaaga gagcggcatc tgggaactgt ttatccctgg ggcgcataac
      421 ggtcagctct ataaatacga gatgattgat gccaatggca acttgcgtct gaagtccgac
      481 ccttatgcct ttgaagcgca aatgcgcccg gaaaccgcgt ctcttatttg cgggctgccg
      541 gaaaaggttg tacagactga agagcgcaaa aaagcgaatc agtttgatgc gccaatctct
      601 atttatgaag ttcacctggg ttcctggcgt cgccacaccg acaacaattt ctggttgagc
      661 taccgcgagc tggccgatca actggtgcct tatgctaaat ggatgggctt tacccacctc
      721 gaactactgc ccattaacga gcatcccttc gatggcagtt ggggttatca gccaaccggc
      781 ctgtatgcgc caacccgccg ttttggtact cgcgacgact tccgttattt cattgatgcc
      841 gcacacgcag ctggtctgaa cgtgattctc gactgggtgc caggccactt cccgactgat
      901 gactttgcgc ttgccgaatt tgatggcacg aacttgtatg aacacagcga tccgcgtgaa
      961 ggctatcatc aggactggaa cacgctgatc tacaactatg gtcgccgtga agtcagtaac
     1021 ttcctcgtcg gtaacgcgct ttactggatt gaacgttttg gtattgatgc gctgcgcgtc
     1081 gatgcggtgg cgtcaatgat ttatcgcgac tacagccgta aagaggggga gtggatcccg
     1141 aatgaatttg gcgggcgcga gaatcttgaa gcgattgaat tcttgcgtaa taccaaccgt
     1201 attcttggtg agcaggtttc cggtgcggtg acaatggctg aggagtctac cgatttccct
     1261 ggcgtttctc gtccgcagga tatgggcggt ctgggcttct ggtacaagtg gaacctcggc
     1321 tggatgcatg acaccctgga ctacatgaag ctcgacccgg tttatcgtca gtatcatcac
     1381 gataaactga ccttcgggat tctctacaac tacactgaaa acttcgtcct gccgttgtcg
     1441 catgatgaag tggtccacgg taaaaaatcg attctcgacc gcatgccggg cgacgcatgg
     1501 cagaaattcg cgaacctgcg cgcctactat ggctggatgt gggcattccc gggcaagaaa
     1561 ctactgttca tgggtaacga atttgcccag ggccgcgagt ggaaccatga cgccagcctc
     1621 gactggcatc tgttggaagg cggcgataac tggcaccacg gtgtccagcg tctggtgcgc
     1681 gatctgaacc tcacctaccg ccaccataaa gcaatgcatg aactggattt tgacccgtac
     1741 ggctttgaat ggctggtggt ggatgacaaa gaacgctcgg tgctgatctt tgtgcgtcgc
     1801 gataaagagg gtaacgaaat catcgttgcc agtaacttta cgccggtacc gcgtcatgat
     1861 tatcgcttcg gcataaacca gccgggcaaa tggcgtgaaa tcctcaatac cgattccatg
     1921 cactatcacg gcagtaatgc aggcaatggc ggcacggtac acagcgatga gattgccagc
     1981 cacggtcgtc agcattcact aagcctgacg ctaccaccgc tggccactat ctggctggtt
     2041 cgggaggcag aatgacacaa ctcgccattg gcaaacccgc tcccctcggc gcgcattacg
     2101 acggtcaggg cgtcaacttc acacttttct ccgctcatgc cgagcgggta gaactgtgtg
     2161 tctttgacgc caatggccag gaacatcgct atgacttgcc agggcacagt ggcgacattt
     2221 ggcacggtta tctgccggat gcgcgcccgg gtttgcgtta tggttatcgc gttcatggcc
     2281 cctggcaacc cgccgagggg catcgcttta acccggcgaa gttgttgatt gatccttgcg
     2341 cgcggcaaat tgacggggag tttaaagata acccgctgct gcacgccggt cataatgaac
     2401 ctgactatcg cgacaacgcc gccattgcgc cgaaatgcgt agtggtggtt gatcactatg
     2461 actgggaaga tgatgccccg ccgcgcacgc cgtggggcag caccatcatt tatgaagccc
     2521 atgtcaaagg attaacgtac ttgcacccgg agatcccggt cgagatccgt ggcacttata
     2581 aagccctcgg gcatccggtg atgatcaact atttgaaaca attgggcatt accgcgctgg
     2641 aactgctgcc agtggcgcag tttgccagtg aaccacgtct gcaacgcatg gggctaagta
     2701 actactgggg ttacaacccg gtggcgatgt ttgcgctgca tccggcgtat gcctgctcgc
     2761 cagaaacggc gctggatgag tttcgcgatg caatcaaagc actgcataaa gcgggtatcg
     2821 aagtcattct tgatatcgtg ctcaaccata gtgcggaact ggacctcgac ggcccgttat
     2881 tctcgctgcg tgggatcgat aaccgtagct attattggat aagagaagac ggcgattatc
     2941 acaactggac cggttgcggc aacacgctca atttgagtca tccggcggtg gtggattatg
     3001 ccagcgcctg cctgcgttat tgggtagaaa cctgccacgt cgatggtttc cgctttgatc
     3061 tggcggcagt catgggccgt acgccagagt tccgtcagga tgcgccgttg tttaccgcta
     3121 tccagaactg cccggtgctc tcgcaggtga agttaattgc tgaaccgtgg gatatcgctc
     3181 ctggtggtta tcaggtggga aatttcccgc cgctgtttgc cgagtggaac gatcatttcc
     3241 gcgatgctgc ccgtcgtttc tggctacatt atgatttgcc tctgggggcg tttgccgggc
     3301 gttttgctgc ctccagcgat gtttttaaac gtaatggtcg tctgccgagt gccgcgatta
     3361 atctcgtcac cgcgcatgac ggttttacgc ttcgcgactg cgtttgcttc aaccataaac
     3421 acaatgaagc aaacggagaa gaaaatcgcg acgggaccaa caacaattac agtaacaatc
     3481 atggtaaaga agggttaggc ggttctcttg acctggttga acggcggcgc gacagcattc
     3541 acgccctgtt aacaacgttg ttgctctccc agggtacgcc gatgttactg gccggtgacg
     3601 aacatggtca cagccagcat ggcaataaca atgcctactg tcaggataac caattaacct
     3661 ggttggactg gtcgcaggca agcagtggtt taaccgcatt taccgccgcg ttaatccatc
     3721 tgcgcaagcg cattcccgct ttggtggaga atcgctggtg ggaagaaggc gacggcaatg
     3781 tccgttggct aaatcgatat gctcaacctt taagcacgga tgagtggcaa aacgggccga
     3841 aacagctgca aattctgctc tcggatcgct ttttgatcgc aattaacgcc acgcttgagg
     3901 taacagagat tgttttacct gctggggagt ggcacgccat tcccccattc gctggagagg
     3961 ataacccagt gattacggct gtctggcagg gacctgcaca cggattgtgt gtgttccaga
     4021 gatgataaaa aaggagttag tcatggttag tttagagaag aacgatcact taatgttggc
     4081 gcgccagctg ccattgaaat ctgttgccct gatactggcg ggaggacgtg gtacccgcct
     4141 gaaggattta accaataagc gagcaaaacc ggccgtacac ttcggcggta agttccgcat
     4201 tatcgacttt gcgctgtcta actgcatcaa ctccgggatc cgtcgtatgg gcgtgatcac
     4261 ccagtaccag tcccacactc tggtgcagca cattcagcgc ggctggtcat tcttcaatga
     4321 agaaatgaac gagtttgtcg atctgctgcc agcacagcag agaatgaaag gggaaaactg
     4381 gtatcgcggc accgcagatg cggtcaccca aaacctcgac attatccgcc gttataaagc
     4441 ggaatacgtg gtgatcctgg cgggcgacca tatctacaag caagactact cgcgtatgct
     4501 tatcgatcac gtcgaaaaag gcgcacgttg caccgttgct tgtatgccag taccgattga
     4561 agaagcctcc gcatttggcg ttatggcggt tgatgagaac gataaaatta tcgaattcgt
     4621 tgaaaaacct gctaacccgc cgtcaatgcc gaacgatccg agcaaatctc tggcgagtat
     4681 gggtatctac gtctttgacg ccgactatct gtatgaactg ctggaagaag acgatcgcga
     4741 tgagaactcc agccacgact ttggcaaaga tttgattccc aagatcaccg aagccggtct
     4801 ggcctatgcg cacccgttcc cgctctcttg cgtacaatcc gacccggatg ccgagccgta
     4861 ctggcgcgat gtgggtacgc tggaagctta ctggaaagcg aacctcgatc tggcctctgt
     4921 ggtgccggaa ctggatatgt acgatcgcaa ttggccaatt cgcacctaca atgaatcatt
     4981 accgccagcg aaattcgtgc aggatcgctc cggtagccac gggatgaccc ttaactcact
     5041 ggtttccggc ggttgtgtga tctccggttc ggtggtggtg cagtccgttc tgttctcgcg
     5101 cgttcgcgtg aattcattct gcaacattga ttccgccgta ttgttaccgg aagtatgggt
     5161 aggtcgctcg tgccgtctgc gccgctgcgt catcgatcgt gcttgtgtta ttccggaagg
     5221 catggtgatt ggtgaaaacg cagaggaaga tgcacgtcgt ttctatcgtt cagaagaagg
     5281 catcgtgctg gtaacgcgcg aaatgctacg gaagttaggg cataaacagg agcgataatg
     5341 caggttttac atgtatgttc agagatgttc ccgctgctta aaaccggcgg tctggctgat
     5401 gttattgggg cattacccgc agcacaaatc gcagacggcg ttgacgctcg cgtactgttg
     5461 cctgcatttc ccgatattcg ccgtggcgtg accgatgcgc aggtagtatc ccgtcgtgat
     5521 accttcgccg gacatatcac gctgttgttc ggtcattaca acggggttgg catttacctg
     5581 attgacgcgc cgcatctcta tgatcgtccg ggaagcccgt atcacgatac caacttattt
     5641 gcctataccg acaacgtatt gcgttttgcg ctgctggggt gggttggggc agaaatggcc
     5701 agcgggcttg acccattctg gcgtcctgat gtggtgcatg cgcacgactg gcatgcaggc
     5761 cttgcgcctg cgtatctggc ggcgcgcggg cgtccggcga agtcggtgtt tactgtgcac
     5821 aacctggcct atcaaggcat gttttatgca catcacatga atgacatcca attgccatgg
     5881 tcattcttta atattcatgg gctggaattc aacggacaaa tctctttcct gaaggccggt
     5941 ctgtactatg ccgatcacat tacggcggtc agtccaacct acgctcgcga gatcaccgaa
     6001 ccgcagtttg cctacggtat ggaaggtctg ttgcaacagc gtcaccgtga agggcgtctt
     6061 tccggcgtac tgaacggcgt ggacgagaaa atctggagtc cagagacgga cttactgttg
     6121 gcctcgcgtt acacccgcga tacgttggaa gataaagcgg aaaataagcg ccagttacaa
     6181 atcgcaatgg ggcttaaggt tgacgataaa gtgccgcttt ttgcagtggt gagccgtctg
     6241 accagccaga aaggtctcga cctggtgctg gaagccttac cgggtcttct ggagcagggc
     6301 gggcagctgg cgctactcgg cgcgggcgat ccggtgctgc aggaaggttt ccttgcggcg
     6361 gcagcggaat accccggtca ggtgggcgtt cagattggct atcacgaagc attttcgcat
     6421 cgcattatgg gcggcgcgga cgtcattctg gtgcccagcc gttttgaacc gtgcggctta
     6481 acgcaacttt atggattgaa gtacggtacg ctgccgttag tgcggcgcac cggtgggctt
     6541 gctgatacgg tttctgactg ttctcttgag aaccttgcag atggcgtcgc cagtgggttt
     6601 gtctttgaag atagtaatgc ctggtcgctg ttacgggcta ttcgacgtgc ttttgtactg
     6661 tggtcccgtc cttcactgtg gcggtttgtg caacgtcagg ctatggcaat ggattttagc
     6721 tggcaggtcg cggcgaagtc gtaccgtgag ctttactatc gcttgaaata gttttcagga
     6781 aacgcctata tgaatgctcc gtttacatat tcatcgccca cgcttagcgt agaagctctt
     6841 aagcactcta tcgcttacaa gctgatgttt acgattggaa aggacccggt cgtcgccaat
     6901 aaacatgaat ggctgaacgc aacgttattt gctgtgcgcg atcgtctcgt ggagcgctgg
     6961 ttacgttcaa accgtgccca gttgtcgcaa gaaactcgtc aggtttacta cctgtcgatg
     7021 gagtttttga ttggccgtac gctctccaac gccatgttgt cgctaggaat ttacgaagat
     7081 gtacagggcg cactggaagc gatggggtta aatctcgaag agctgattga tgaagaaaat
     7141 gacccaggcc tcggtaacgg tggcctggga cgtctggcgg cttgcttcct tgattctctg
     7201 gcgacgttag ggttgccggg gcgcggttac ggcatccgct atgactacgg tatgttcaag
     7261 cagaacatcg ttaacggtag ccagaaagag tcgccagact actggctgga atacggtaac
     7321 ccgtgggaat tcaaacgcca caacacgcgc tataaagtcc gttttggcgg tcgcattcag
     7381 caggaaggta aaaaaacgcg ctggattgaa accgaagaga ttctgggagt cgcttacgat
     7441 cagataatcc ctggttacga caccgacgcg accaacacgc tgcgtttgtg gagtgcgcaa
     7501 gccagtagcg aaattaacct cggtaaattc aaccagggtg actacttcgc ggcagtggaa
     7561 gataaaaacc actccgagaa cgtatctcgc gtactgtatc cggatgactc cacctactcc
     7621 gggcgtgagc tgcgcctgcg tcaggaatac ttcctggttt cctcgaccat tcaggacatt
     7681 ttaagccgcc attatcagtt gcataaaacc tacgataacc tggcggataa aatcgcgatt
     7741 catctcaatg atacccatcc ggtactgtcg attcctgaga tgatgcgtct gctgatcgat
     7801 gagcaccaat ttagctggga cgacgcgttt gaggtgtgtt gtcaggtctt ctcctacact
     7861 aaccacacgc tgatgagcga ggcgctggaa acctggccgg ttgatatgct gggtaaaatt
     7921 ctgccgcgtc acctgcagat catctttgaa atcaacgact atttcctgaa aaccttgcag
     7981 gaacagtatc cgaacgatac cgatctgctg ggacgggcgt cgatcattga tgaatccaac
     8041 ggtcgtcgtg tgcgtatggc ctggctggcg gttgttgtga gccacaaagt taacggtgta
     8101 tcggaactgc actctaatct gatggtgcaa tcgttgtttg ccgactttgc gaaaatcttc
     8161 ccgggtcgtt tcaccaacgt caccaacggt gtgacgccgc gtcgctggct ggcggtagcg
     8221 aacccatcgc tttcagccgt gctggacgaa cacctgggcc gtaactggcg caccgacctt
     8281 agcctgctta atgagctgca acaacactgt gatttcccaa tggttaatca cgctgtgcat
     8341 caggcgaagc tggagaacaa aaagcgtctg gcagagtata tcgcccagca gctgaatgtg
     8401 gtggtgaatc caaaggcgtt gttcgatgta caaatcaaac gtattcacga atacaaacgt
     8461 caattgatga atgtgttgca tgtgattacc cgctataacc gcatcaaggc cgacccggat
     8521 gcgaagtggg taccgcgcgt gaatattttt ggcggtaagg cggcttcggc ctattacatg
     8581 gcgaagcaca ttattcattt gatcaatgac gtagcgaaag tgatcaacaa cgatccgcag
     8641 attggcgata agctgaaagt cgtgttcatc ccgaactaca gcgttagcct ggcgcagttg
     8701 atcattccgg cggcagatct gtctgaacag atttcgctgg cagggacgga agcttccggc
     8761 accagtaaca tgaagtttgc gcttaacggt gcgctgacta tcggtacgtt ggacggtgcg
     8821 aatgtcgaga tgctggatca tgtcggtgct gacaatatct ttatttttgg taacacagcg
     8881 gaaaaagtgg aagaactgcg tcgtcagggc tacaaaccgc gtgaatacta cgagaaagat
     8941 gaggagctgc atcaggtgct gacgcaaatc ggcagcggtg tattcagtcc ggaagatccg
     9001 ggtcgctatc gcgatctggt tgattcgctg atcaacttcg gcgatcacta ccaggtactg
     9061 gcggattatc gcagctatgt cgattgtcag gataaagtcg atgaactcta cgagcttcag
     9121 gaagagtgga ccgcaaaagc gatgctgaac attgccaata tgggctactt ctcttctgac
     9181 cgtactatca aagagtacgc cgatcatatc tggcatatcg atccggtgag attgtaagtt
     9241 caccaataaa tagaacgggg ccaaagggtc ccgttttttt ccgccatcat ttcggaaaag
     9301 tgtccagaag gggcaagggg actcggggag tataatttca ccattcaaaa agaatggaaa
     9361 gaataatgca aaacagaaaa tggattttga cctcgctggt aatgactttt ttcggcatcc
     9421 ccatactggc gcaatttttg gcggtggtta ttgccatgct gggtgtcgga cttgccggta
     9481 ttattgaagt ttgtaatatc cttatcacgc caacaattta ccttctgctc aaaattttta
     9541 tgctggcgct gggcgcatta atgctatttt tctcggggcg agtggggaac gtgcctgagt
     9601 tttgttacgt tgggtatgat ggcgtgggct ttgcggtaat tccctgaatt aaaaagtagg
     9661 ttagattttt gacaaagtgc gctttgttca tgccggatgc gacgtgaacg tcttatctgg
     9721 cctacaagac catgcaaatt caatatattg cataaaccac gtaggcctga taagcgtagc
     9781 gcatcaggca gttttgtgtt tgtcatcagt ctcaggccag attgaaatct gacctgatca
     9841 ccttacgtta atttacgacg ccagcgataa cctctgctgc gtatactcca ccagccactg
     9901 actcacacga gattgttgat ccgcatttag ccacatgcct tgttttgtgc gacgccacag
     9961 ggcgtcgtcg gcgcggcgga cccattcgtg atccaccagg tatttcagct ccgcttcgta
    10021 gaactcatga ccgaaatctt ccccgagatc gcttaccgtt cccgcattgc cgagcagcag
    10081 ctcgctgttg ctgccgtaag tgcgagcgta atgacgcgcc agcgattcag tcaggaacgg
    10141 atagcggcgg cgcaggcgag cggcataatc gtcgcggtcg ccttcaatgg cgccacccgg
    10201 tagcacactc tctttcgtcc atgccgggcc aataccctga taatacggcg ttagtttttc
    10261 cagcgcatgt tccgccagtt ttcggtaggt ggtcagctta ccgccgaata ccgacagcag
    10321 cggtgctttg ccattttcat catgaatatc aagggtgtaa tcacgggtaa tagcctgcgg
    10381 cgagtcggac tcatcatcac acagcggacg cacaccggag taggtccaga cgatatcgtc
    10441 acggcttaac tgctttttaa agtgcgtgtt atacacattc agcaggtaat tgatttcact
    10501 ctcttcaatc ttcaccgctt tcggatcgcc tttgtactcg acatcggtag tgccgatgat
    10561 ggaaaactcg tccatccacg ggatcacgaa cacaatacgt ttatcttcgt tttgcagaat
    10621 gtaggcttgc ttctgggtat gcacgcgcgg caccacaata tggctgcctt tgatcaggcg
    10681 aatgccataa ggcgaaggca gatgcatccc gtcgtcgaag aactgtttca cccacgggcc
    10741 ggtggcgtta accaagccgc gcgcttgcca gctatatttt ttgccggtat cgatatcttc
    10801 cgcttccaca atccacaggc cgttttcgcg gcgagcagag gtggcgcgag tccgagtaag
    10861 cacttcgccg cctttacgca ccaccatctg ggcgttggcg agtaccagac gggcgtcgtc
    10921 tacccaacag tcagaatatt cgaatccgcg cttaatttcc ggttttaaca ctgaatttgc
    10981 gccaaaacgc aaaccagttg atcccggcaa gctggtgcgt ttacccagat gatcgtacat
    11041 aaacagacca atgcgaatca tccacgccgg gcgcagatgc ggacgatgtg gcaggcgaaa
    11101 acgcatcggg aaggcgatat gcggggccat tttcagcagc acttcacgtt cagccagcgc
    11161 ctcgctgacc aggcggaatt catagtgctc aaggtagcgc aggccaccgt gaatgagttt
    11221 tgaactggcg gaagaggtcg cgcaagcgag atcctgcgcc tccagcatca gcacggataa
    11281 accgcgtcca gcggcgtctg ccgcgatacc agcaccattg atgccgcccc ctatcacaat
    11341 cagatctttg gtttccatgc tgccctcatt cactttcgtt aaagctcata aatgttcgtt
    11401 atcgaacata ttagcaaaga atcgcgcttt aggtaacatt gaaaaaacat tttagagtga
    11461 tatgtataac attatggcgt ttatctgccg cttcgacgta aactgtgcgg taaatttgcc
    11521 cacttgtttg taaagaaaga gagacgcatg gatcagttcg aatgtattaa cgttgccgac
    11581 gcgcaccaga agttgcagga aaaagaggcg gtgctggtcg atattcgcga tccacagagt
    11641 ttcgcaatgg gacatgcggt gcaggctttc catttaacca acgacacgct gggcgctttt
    11701 atgcgtgata acgactttga cactccggtg atggtgatgt gttatcacgg caatagcagc
    11761 aaaggcgcgg cgcagtatct gctgcaacag ggctacgatg tggtctatag cattgacggc
    11821 ggctttgaag cctggcaacg tcagtttccc gcagaggtgg cgtacggcgc gtaacgcttt
    11881 atactgtccc cttttgtgtg gaataagcga cagcaacgat gttgatgatt acctcttttg
    11941 ctaacccccg cgtggcgcag gcgtttgttg attacatggc gacgcagggt gttatcctca
    12001 cgattcaaca acataaccaa agcgatgtct ggctggcgga tgagtcccag gccgagcgcg
    12061 tacgggcgga gctggcgcgt tttctcgaaa acccggcaga tccgcgttat ctggcggcga
    12121 gctggcaggc aggccatacc ggcagtggcc tgcattatcg ccgttatcct ttctttgccg
    12181 ccttgcgtga acgcgcaggt ccggtaacct gggtgatgat gatcgtctgc gtggtggtgt
    12241 ttattgccat gcaaattctc ggcgatcagg aagtgatgtt atggctggcc tggccattcg
    12301 atccaacact gaaatttgag ttctggcgtt acttcaccca cgcgttaatg cacttctcgc
    12361 tgatgcatat cctctttaac ctgctctggt ggtggtatct cggcggtgcg gtggaaaaac
    12421 gcctcggtag cggtaagcta attgtcatta cgcttatcag cgccctgtta agcggctatg
    12481 tgcagcaaaa attcagcggg ccgtggtttg gcgggctttc tggcgtggtg tatgcgctga
    12541 tgggctacgt ctggctacgt ggcgaacgcg atccgcaaag tggcatttac ctgcaacgtg
    12601 ggttaattat ctttgcgctg atctggattg tcgccggatg gtttgatttg tttgggatgt
    12661 cgatggcgaa cggagcacac atcgccgggt tagccgtggg tttagcgatg gcttttgttg
    12721 attcgctcaa tgcgcgaaaa cgaaaataat tccagggatt tataaatgaa acaaacacaa
    12781 cgtcacaacg gtattatcga actggttaaa cagcagggtt atgtcagtac cgaagagctg
    12841 gtagagcatt tctccgtcag cccgcagact attcgccgcg acctcaatga gctggcggag
    12901 caaaacctga tcctgcgcca tcatggcggt gcggcgctgc cttccagttc ggttaacacg
    12961 ccgtggcacg atcgcaaggc cacccagacc gaagaaaaag agcgcatcgc ccgcaaagtg
    13021 gcggagcaaa tccccaatgg ctcgacgctg tttatcgata tcggcaccac gccggaagcg
    13081 gtagcgcacg cactgctcaa tcacagcaat ttgcgcattg tcaccaacaa tctcaacgtt
    13141 gctaacacgt tgatggtaaa agaagatttt cgcatcattc tcgccggtgg cgaattacgc
    13201 agccgcgatg gcgggatcat tggcgaagcg acgctcgatt ttatctccca gttccgcctt
    13261 gatttcggca ttctggggat aagcggcatc gatagcgacg gctcgctgct ggagttcgat
    13321 taccacgaag ttcgcaccaa acgcgccatt attgagaact cgcgccacgt tatgctggtt
    13381 gtcgatcact cgaaatttgg ccgtaacgcg atggtcaata tgggcagcat cagcatggta
    13441 gatgccgtct acaccgacgc cccgccgcca gtaagcgtga tgcaggtgct gacggaccac
    13501 catattcaac tggagctgtg ctgatcctgc acggcttccc acgtcagacc aaaacgcgcc
    13561 aggtatttgc gtagccgatc cgcgtcattg acgctggctt tgccctggcg cgaaacgtca
    13621 aaaagctggc gtccggctgc ggaaagcgac tttgcctggc ggcagatagc gataacgtgt
    13681 tccagttgca tacggtcgaa gagatcgatg ttttctgcct ctgcgcccag caacgccgta
    13741 agcgcggagg ggcggctctc ctgccagtta tagcgcagac ggtttatctc atcttcaacc
    13801 acgtccagag tgatgcgtcc gctagtggca aaggtggcca tccgcgtgac gctggcagaa
    13861 agttcgcgaa agttaccgcg ccatgttgcc tggggagagg tcgcaaaagc caaccaggcg
    13921 cgccgcgctt cggtgttaaa acgcacgctg tcgccagtga gtgaggcgtg gcgctccact
    13981 tcataatcca ggttcggttc aatatcttcc tggcgctggc gtagacccgg cagggtgaag
    14041 gtccagagat tgatccgcgc gtacagatct tcgcgaaatt tgccttcggc aaccagctgg
    14101 cgcaaatcgc gcaccgttcc ggcgataagc tgaaaatcac tgctcacctg gcgatcgctg
    14161 ccaaacgggt aaaaggtttt ctcttcaatg gctttcagca gcattgcctg ttcgtctgcg
    14221 cccagttcgc caatctcatc aagaaacaac attccgccgt tggcgctgcg taataaacct
    14281 tcacgagatt cccgcgcccc ggtaaacgcg ccttttacat gaccaaacag cgtcgacatg
    14341 gcggtatcgc cgcgcagggt ggcgcagttc acttccacaa acgcgccgct aaactgatgc
    14401 cgcgcctgtt ttaactcgaa gatgcgtcgc gccagaaatg acttgcccgc gccggttgga
    14461 ccgttaagca gaatcggcgc gcgggatttg atcgccactt tttcgatctg ctcaatcatg
    14521 cggttgaagt gggggttacg cgtggcaatg ccggacttaa gaaaatcaag cgtttgctgg
    14581 cgttcctcgg caaagcggct ggcgatggcg ttataacggc ttaaatcgag atcgataatc
    14641 gttacttcac ctgggccgcg cggctgttct tttttgcgcg gaggtgaaga ttgtatcagc
    14701 cgggcgggca ggtaacgcgc ttctgccagc agaaaccagc aaatctgcgc gacgtgggta
    14761 ccggtggtga tgtgaattaa atagtcttct ttttctggct gaaactcgta accacgggcg
    14821 aaatcatgca ggcaggcgta gacctcttcg aaatcccacg ggttatgcag ttcaatctca
    14881 acgctcacca cttctgtttc tggcgaaacg ctggcgatat cgcgtttaag cgtttcaaat
    14941 agcgagcgcg agcgggcgtc gtgcaacaat tccagtcgat cgatgaccaa cgattcttgc
    15001 tggcataaac agagtgtcgg acgccatttt gaccagcgct gactgccgcg cccggcataa
    15061 tccagtacgg taccgacaaa gccaaaagcc actgttttac gcatcttaga tatccttata
    15121 aaagacgata tttcattatc ggtaaattgg ctttgcggga aatctccggt
//
LOCUS       DACAOP010000102        15025 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.102, whole genome shotgun sequence.
ACCESSION   DACAOP010000102 DACAOP010000000
VERSION     DACAOP010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15025
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.102"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..240)
                     /gene="murF"
                     /locus_tag="IT892_003632"
     CDS             complement(<1..240)
                     /gene="murF"
                     /locus_tag="IT892_003632"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAP3136796.1"
                     /translation="MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIV"
     gene            complement(237..1724)
                     /gene="murE"
                     /locus_tag="IT892_003633"
     CDS             complement(237..1724)
                     /gene="murE"
                     /locus_tag="IT892_003633"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HAP3136797.1"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVEQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     IDVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTALGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     gene            complement(1711..3489)
                     /locus_tag="IT892_003634"
     CDS             complement(1711..3489)
                     /locus_tag="IT892_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HAP3136798.1"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSHAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTIPY
                     RINYRINGHEIKDVARYSKLTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKA
                     TNLGLVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSI
                     TKVDPPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPD
                     GRYINKYIAYTAGVAPASQPRFALVVVLNDPQAGKYYGGAVSAPVFGAIMGGVLRTMN
                     IEPDALTTGDKNEFVINQGEGTGGRS"
     gene            complement(3505..3870)
                     /gene="ftsL"
                     /locus_tag="IT892_003635"
     CDS             complement(3505..3870)
                     /gene="ftsL"
                     /locus_tag="IT892_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAP3136799.1"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     gene            complement(3867..4808)
                     /gene="rsmH"
                     /locus_tag="IT892_003636"
     CDS             complement(3867..4808)
                     /gene="rsmH"
                     /locus_tag="IT892_003636"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAP3136800.1"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     gene            complement(4810..5268)
                     /gene="mraZ"
                     /locus_tag="IT892_003637"
     CDS             complement(4810..5268)
                     /gene="mraZ"
                     /locus_tag="IT892_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAP3136801.1"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIYHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     gene            complement(5870..6874)
                     /gene="cra"
                     /locus_tag="IT892_003638"
     CDS             complement(5870..6874)
                     /gene="cra"
                     /locus_tag="IT892_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite repressor/activator"
                     /protein_id="HAP3136802.1"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     gene            complement(6956..7042)
                     /locus_tag="IT892_003639"
     CDS             complement(6956..7042)
                     /locus_tag="IT892_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fruR/shl operon leader peptide"
                     /protein_id="HAP3136803.1"
                     /translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
     gene            complement(7054..7545)
                     /gene="ilvN"
                     /locus_tag="IT892_003640"
     CDS             complement(7054..7545)
                     /gene="ilvN"
                     /locus_tag="IT892_003640"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HAP3136804.1"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSGKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     gene            complement(7548..9272)
                     /gene="ilvI"
                     /locus_tag="IT892_003641"
     CDS             complement(7548..9272)
                     /gene="ilvI"
                     /locus_tag="IT892_003641"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025294.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="HAP3136805.1"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     TAGCHQQLKETVEALNLPVVCSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPHELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     gene            9391..9435
                     /locus_tag="IT892_003642"
     CDS             9391..9435
                     /locus_tag="IT892_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136806.1"
                     /translation="MKRNDKILHYRGLN"
     gene            complement(9590..10534)
                     /gene="leuO"
                     /locus_tag="IT892_003643"
     CDS             complement(9590..10534)
                     /gene="leuO"
                     /locus_tag="IT892_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414618.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="HAP3136807.1"
                     /translation="MPEVQTDHPETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     VLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQPWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
     gene            11194..11280
                     /gene="leuL"
                     /locus_tag="IT892_003644"
     CDS             11194..11280
                     /gene="leuL"
                     /locus_tag="IT892_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="HAP3136808.1"
                     /translation="MTHIVRFIGLLLLNASSLRGRRVSGIQH"
     gene            11373..12944
                     /gene="leuA"
                     /locus_tag="IT892_003645"
     CDS             11373..12944
                     /gene="leuA"
                     /locus_tag="IT892_003645"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HAP3136809.1"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITEYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQHNENNKETV"
     gene            12944..14035
                     /gene="leuB"
                     /locus_tag="IT892_003646"
     CDS             12944..14035
                     /gene="leuB"
                     /locus_tag="IT892_003646"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HAP3136810.1"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAACAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     gene            14038..>15025
                     /gene="leuC"
                     /locus_tag="IT892_003647"
     CDS             14038..>15025
                     /gene="leuC"
                     /locus_tag="IT892_003647"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HAP3136811.1"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLK"
BASE COUNT         3757 a         4077 c         3670 g         3521 t
ORIGIN      
        1 gacgattaac tgcggcaggt cgatgtccag cggacggcta accagtagtg cgcctgcgcc
       61 gccagctttc gcctggtcgg caaaatcgtg ggcatcaaaa cgttcgcctt tcagggcaac
      121 aaacaggcag cccggcgtca gttttcgggt atcagtggtt acagcatcaa gggtgatatc
      181 tgcaccttgc agttcaccgt tgagaatgtc ggtaagttgg ctaagggtta cgctaatcat
      241 gcaatcaccc ccagcagacg cgccaccgtg acgcgatcgg agtagtccag acgctgattg
      301 ccaacaatct ggtaatcttc atggcctttg cccgcgacca gtaccacatc attctcttta
      361 gcctgcataa cggcgcaagt caccgcttca gcacggcctt ccatcacttt ggcatgtccg
      421 gcatctaaca ttcccgccag aatatcgttg atgatggcac gcggttcttc ggtacgcggg
      481 ttatcgtccg tcaccaccgc cacgtcagca aactcttcgg caattgcgcc catcagtgga
      541 cgcttacctt tatcgcgatc gccaccacag ccaaagacgc accacagctt gcccgcacag
      601 tgcaggcgcg ccgcctgtaa ggctttttcc agtgcatccg gcgtatgcgc gtaatccacc
      661 accaccgtcg gtttgcctag cgcagtgaac acttccatac gtccgcaaac cggttgcaga
      721 cgcgcggcgg ttttcagcag atcagccagt ggatagccga gtgccagcag tgtcgccagc
      781 gcgagcagca ggttgctgac gttaaaagcg cccatcagat ggctttcaat ttcgccatcg
      841 ccccaacttg agctaaagcg aatcgtcgca ccgctgtcgt gatagttcac gtcgatcgct
      901 tttaaccagc gtccgtgaca gttcggattg atatgatctt ccattgatac cgcaaccgcg
      961 tccggcagtt ttgccagcca gcggcggccc acttcatcgt cggcgttaat aatcgcctga
     1021 ccgcaatgat gttcagaata aagcagccat ttcgcagctt cgtagtgttc catatcacca
     1081 tgataatcaa ggtgatcgcg gcttaagttg gtaaagaccg acgccgcaaa tttcaatgcc
     1141 gccacacggt gctgtaccag cccgtgggag gaaacttcca ttgcgcaaaa cgtcgcgccc
     1201 tgctccacca gccccgccag ctcatgctga acatcgactg ccgaaccggt agtattttct
     1261 gtcgggatca ctttcccaag cagaccgtta ccaacggtgc ccattaccgc gctggtttcg
     1321 ccaagcagtt ggctccactg cgccagcagc tgggtagtcg tggttttgcc gttggtgccc
     1381 gttacgccta cgagacgtaa attgtcagag ggttcatggt aaaagcggcc cgccagtgca
     1441 gataaacgct cgttgagctg gctgagatag atgaccggta cgccgtgcat ttcacggatt
     1501 tcaccatcgg tcgcctcatc tttcgcctct gcaataatgg cagccacacc ttgcgctatc
     1561 gcctgcggga tatatcgacg cccgtccgcc tgatgaccta ctacagctac aaagagatcg
     1621 cccgccgcag ccacacggct gtcgagtgtc atctctcgca gtgctcgcga aggtgcgtct
     1681 ggcacccacg gagcaagaag gtcgcgcaaa ttacgatctg ccacctgtcc cctcgccttg
     1741 attaatcaca aattcatttt tatcgcccgt tgtcagcgca tccggctcga tgttcatggt
     1801 acgcaatacg ccgcccatga tggcaccaaa gaccggcgcg gaaacggcgc cgccgtagta
     1861 tttacccgcc tgcggatcgt tgagaacaac aaccagcgcg aagcgcggct gactcgcagg
     1921 cgcaacgcct gcggtataag caatatattt attgatgtag cgaccgtccg gcccgacctt
     1981 tttcgcggta ccggttttaa tggcgatacg atagccttta atcgccgctt tcacgccgcc
     2041 gccgcctggt agcgccacgc tttccatcat atgcaccacg gtgcgaacaa tggattccgg
     2101 gaagacacgt tcaccgggaa ccggggggtc aactttggta atcgacagtg ggcgataaat
     2161 gccgtagctg ccgatagttg cgtagactcg cgctaactgt aacggtgtta ccattagccc
     2221 gtagccgaaa gagaaggtgg ccctctctat gtcagaccac cgttgttttt gaggatataa
     2281 gccactgcgt tctccgacca accccaaatt ggtcgctttt cccagtccaa aacgtgagta
     2341 agtatctact aacgctgagg acggcatcgc taacgccagc ttggaaacac cgacgttact
     2401 cgacttctgt aataccccgg tcagggttaa tttgctgtag cgtgccacgt ctttgatttc
     2461 gtggccgtta attcgatagt taattcgata aggaatggta ttgagtaccg agttttcccg
     2521 caccacgcca cgttgcaacg cggtcattac caccatcggt ttaaccgttg agcccggttc
     2581 aaacacgtcg gtgatggtac ggttacgcat cgcctctttc ggcgtgccgc tcagattgtt
     2641 agggttgtat gacgggctgt tagccatcgc cagcacttca ccggtgttga catccaccag
     2701 cacggcgcta ccagattcag ccttgttaaa ggccaccgcg ttgttcagtt cgcgataaac
     2761 cagcgcctgc aggcgttcat caatactcag cgccaggttg tgcgctgcgt ggctgtcagt
     2821 agaagaaata tcttcaatta cgcgaccata gcggtcttta cgcacaatgc gctcacccgg
     2881 ctgcccggta agccatttat cgaaactctt ctcaacgccc tcaatccctt gactatcgac
     2941 gttagtaaag ccgatgaggt gagcagtcac ttcgccggac ggatagtaac ggcgagactc
     3001 ttcacgcaga tgaatccccg gcagtttcag ttttttgatg tagtccgcca tgtcagggtt
     3061 cacctgacgc gccagataaa taaagcgccc tttcgggttg gcgttaatgc gggctgaaag
     3121 ctgatccagc ggaatattga gcgcgttagc cagtgccttc cagcggtcac cgacgctgat
     3181 accgccagcg tcatgcactt ctttcgggtc agcccaaatc gcttttaccg gcacgctcac
     3241 cgctaacggg cgaccagaac ggtcagtaat catgccgcgg gaggtggaaa cttgctgaac
     3301 gcgaagagaa cgcatgtcgc cctctttcac cagcatatcc ggggagataa cttgtaacca
     3361 cgctacgcgt ccgagcagaa aagccagcgc caggagaata cagccgcata acaacgcaaa
     3421 acgccaactg ataaagttgg catgttcttc ctgacgtttt ggtttctgcg ttttcgccgc
     3481 tgctttcatg cgtcgcgttt atccttattt ttgcactacg atattttctt gtgacggatc
     3541 aacatgctgc atttgcagct tttccgtggc gatcctttcc acccggctat ggtcgccgag
     3601 cgcattctct tcaaggatca ggttgcgcca ttcaatgtct aaagcatctc gctccagcac
     3661 cagttgttcg cgctgagcgg tcagtaaacg ggtatggtgc gccgtggtta ccacagtcac
     3721 cgccgtcaaa ataatgcaaa tgaacaggca gagtggcagc ttcccaaatc gcaaaagatc
     3781 gtcaccgata acaccaggca atgcatggcg ctcgtggctt cccatcgatc ctttaacttt
     3841 gcttagagct tctgtcactc tgctgatcat gcattcgtcc tctctgcaat acgcagaact
     3901 gaactacggg cacgagggtt ctcagccacc tcttcttcgc ccggcattaa cttgcctagt
     3961 gctcgcagct gacggccacc cagttttttg agctgctctt cagtcatcgg taaccctgcc
     4021 ggaacttgcg gaccgcggct gttttcacgc ataaaacgtt tcacaatacg gtcttccagc
     4081 gagtggaagc tgatgatcga aagccgccca cccggggcca gcacgttgag cgagcttttt
     4141 agcgcctgct ctatctcctc cagttcactg tttacccaaa tgcgcaccgc ctggaaggta
     4201 cgggtcgcgg gatgtttaaa cttatctttc accggcgttg cagcagccac gacttccgcc
     4261 agttctttgg tgcgggtcat cggctgttcg cggttacgct cgacaatggc gcgggcaatg
     4321 cgtttggcaa aacgctcttc accataggtt ttcaataccc aggcgatatc ggcttcttct
     4381 gcggtttgta gccattcagc ggctgactgc ccacgggttg ggtccatacg catgtccagc
     4441 ggaccatcgc gcataaagga aaagccacgt tcagcatcat caagttgcgg tgaagagacg
     4501 ccaagatcga ggagaatgcc gtcgatcttg ccgataagat cgcgctcggc aacgtattcg
     4561 cccagcgcgg agaaaggtcc gtggatgatg gagaagcgcg gatcatcaat agtcttcgca
     4621 acggcgatag cctgcgggtc gcgatcgatc gccagcaaac gcccctcttc gccaagctgc
     4681 gagaggatca gacgtgagtg accaccgcga ccaaaagtcc catcaatgta gatgccatca
     4741 ggacggatat tgaggccatt aacggcttca tccagcagca ccgtagtatg tttatagttt
     4801 tccatcattt tatagagaca agtcctgcag tcgctccgat aagtctccgg tagccaactg
     4861 ctctgcgtcg atatcttcct tgacctgttg atgccaggtt gtttcatccc acagctcaaa
     4921 cttgttgaac tgtccaacca gcatcacttc ttttgtcagc ccggcatgtt gccgcagtac
     4981 tggcgcgatt aacaatcgac ctgcgccatc catctgacat tcgctggcat gacctaacag
     5041 taggcgctgc acacggcgct caaccgggtt catgctcgac agacgcgata atttttgctc
     5101 gataatttcc cattcaggca gggggtaaag cagcaggcac gggtgataaa tgtcaatggt
     5161 gcaaaccatt tgaccggcag cgttctcaag cagctgttcc cgataacggg taggcactga
     5221 taagcgccct ttgctgtcga gattgactaa cgttgctccc cggaacatgc cagcctcacc
     5281 ccttattccc actttgcccc acaatttccc actgaaagga gtttacggag ctgaggaaaa
     5341 gcttgtcaag ccagtcacaa ggcataccga ggtaaaaaac ccgatgttta cggctaatat
     5401 cagcgttgtt tattttacgt ccaacgtgcg aagcaaatta acgttatgaa tagctgtaag
     5461 aaaaaatccc tcatcgtcat caccgtttta aaatgactca ctattttcca cagcaaatat
     5521 aaagtgtcag tttgcgacgc gagcggcatt ttaggacata tcttccccgg ttaacagtcc
     5581 ttgttacgtc tgtgtggcgc ttgatgccag cgggtttgcg caaaagcaaa gaaaagtgtt
     5641 tgttaaatcg gcaattcatc gccgcatgta acaaaataat gcaaaaacgc gctgtcgata
     5701 tcacttaatt attgtgaatt tcagctggtg agttaattaa cgggcgggtt taaaagcatt
     5761 tatcaataat agtcaggaat agtcttattt actttaagca tattgatgtc cagtcccgta
     5821 ctctacgcgc cagagggaaa ttcacctggc gcgtattttt gttcgcggct tagctacggc
     5881 tgagcacgcc gcggcgatag agattacgtt taatgcgcgt taaaccaggt tttggcttac
     5941 gcggttcgtc caggcttgcc aggacaatct ccagcacacg ctctgcgaca tcgcggtgac
     6001 gttgagccac tgccagcacc ggacactgta agaagtcgag cagttcgtta tcgccaaagg
     6061 tggcaattgc caggtcagaa ggcagtttgc cgtcgcgacg cagcgtgaca tccatcactc
     6121 cttgcaacaa cgcaaacgac gttgtgaaca gcgcctgcgg catcggatgc gtttccagcc
     6181 atttttcgaa taactgggca gccgcctccc gctcatagct gttggcatac aggaaatgca
     6241 cttcgcgcgg atcatctttc caggcagtac ggaaaccttg ttcacgcagg aagctgacag
     6301 aaagctccgg tagcgcacca agataaagca ccgtctcggc gggaaactta cgtaactctt
     6361 ccgccagcat ttcggcatca tcctgatcgg caccaaccac gctggtgaag tgttcacgat
     6421 cgagggcgcg gtccagcgcg acaatcggga acgggtcgtt agcccagcgt tgataaaaag
     6481 gatgctcagg aggcaacgac gtcgaaacaa taatggcatc aacctgacgc tgtaaaaggt
     6541 gctcaatgca ccgcatttcg ttgtctggct gatcttctga gcaggcaatc agcagttgat
     6601 aaccccgttg ccgcgcctgg cgttcaagat agttagcgat gcgggtatag ctggtgttct
     6661 ccagatcggg gatcacaaga ccaatagaac gtgtgcgtcc agcacgaagc ccagctgcca
     6721 cggcgttcgg gtggtaattg tgctcacgca ccacagccat gactttttca acggttttgt
     6781 cgctcacacg gtattgcttc gctttgccgt taataacata gcttgcagtg gtccgcgaca
     6841 ctcccgccag ccgagcgatt tcatccagtt tcacaattgc cccttgcgta aaatgtaaaa
     6901 accatagcca ttgtactggt atgggttaaa ttcattaaca tctaagcgca gaaaattaac
     6961 tgcggcaact gcttttattc caggttccca ctgatttcgc aaaaaaagcc caacgtgaca
     7021 tgttgggctg taaattgcgc attgagatca ttctcaacgc attattttat cgccgcgcga
     7081 aagtccgacc acaccagagc gagcaacctc cacaattttc gccacatcgc gaatcgatgc
     7141 taaaaatgca tcaagcttac cgctggtgcc tgctaattga acggtataaa gcgagggtgt
     7201 gacatcgata atttgcccac ggaatatttc cgtattacgt ttcacttcgt cacgcccgta
     7261 accgctggcc tgaattttca ccagcatgat ttcccgctca acatgcgcgc cctgccccaa
     7321 ctcactcacg cgcaagacat cgaccagttt gtgtaattgc ttttcgatct gctcaagtac
     7381 tttttcatcg cccacggtct ggatggtcat acgcgataat gtcggatcgt cggttggcgc
     7441 aacggtcagg ctttcaatgt tgtagccacg ctgggaaaaa aggccaatca cgcgggataa
     7501 cgcgcctgat tcattttcga gtaagactga taatatccgg cgcataatca ggttctctcc
     7561 gttttgctta accacatttc atccattccg cccccgcgaa tctgcatcgg gtagacgtgc
     7621 tcgctgccat cgacggtaac atcaacaaac accaggcgat tattgcgcac ctgttccagc
     7681 gcctcgctaa gtttgctttc cagctcatgc ggatgagaaa tctggatccc gacatgccca
     7741 taggcttccg ccagacggac gaaatcgggt agcgattgca tataagattg tgaatgacgg
     7801 ccggaataga tcatgtcctg ccactgcttc accatcccca gatagcggtt attgagattc
     7861 accaccagta cgggcaactc gtattgcaac gcggtagaca gttcctggat gttcatctga
     7921 atactgccgt cgccagtgac gcaaaccacg gtttcttctg gcaacgccat tttgacgccc
     7981 agtgccgcag gtaaaccaaa acccatcgtg ccgaggccac cggaattgat ccagcgacgc
     8041 ggtttgtcga atggataata aagtgcagca aacatctggt gctgcccgac atcggacgtc
     8101 acgtaagcgt ctcccttcgt caaccgccaa agagtctcga tcaccgcctg cggtttaatc
     8161 ttttcactgt gagtgtcata tttcaggcac tgacgagcgc gccactgttc aatttgctgc
     8221 caccagtcgc ggatctcatc cagtggttga tgggcggatt cttgcgacaa gagttcaagc
     8281 atttgttcga ggacctggcg agcatccccc acaatcggga tatccgcagt cacggtttta
     8341 gaaatggaag taggatcaat atcgatatgc agaacagtgg catttgggca gtactttgcc
     8401 agattgttcg tcgttcggtc atcaaatcgt accccgacgg cgaaaatcac atccgcgtta
     8461 tgcatcgtca tattggcttc gtaggtaccg tgcattccca gcatgcccag tgcctgacga
     8521 tgcgttgccg gaaacgcccc cagccccatc aatgagcaaa caacgggcag attcaacgcc
     8581 tccaccgttt ctttcaactg ctgatggcag cccgccgtga ttgccccacc gcctacgtag
     8641 acaaccggtt tttttgccgc taccagcgtt tgcagagcac gcttaatttg ccctttatgt
     8701 ccggtagtag tgggattgta agaacgcata ctgaccgact ccggccagac atagggtaat
     8761 ttgttcgccg gattaagaat atctttcggt aaatcaacga ctactggtcc tgggcgacca
     8821 cttgccgcca gccagaaagc ctttttcagc acctgcggaa tgtcttccgt ttgcttaacc
     8881 agaaaactgt gtttaaccac cggtcgcgaa atccccacca tgtcgcactc ctgaaaggca
     8941 tcgtaaccta tcaacgaggt cgctacctgc ccggaaagga caactaatgg aatggaatcc
     9001 atataagcgg tggcgatgcc agtaatcgca ttggtcgccc ctggacccga cgttaccagc
     9061 acgacgccga cttccccggt cgcgcgcgcc aggccatcgg ccatatgcac cgccgcctgc
     9121 tcatgacgaa ctaatacatg atcaatacca cccacggtat gcaatgcatc ataaatatca
     9181 aggactgcgc ctccgggata accgaatact tgtttaacgc cctgatcgat aagcgatcgg
     9241 acgaccatct cggctccaga caacatctcc atggcctgcc tcactgtttg acggaaaaaa
     9301 tgtgtaaaac acattaaccg tccgatcttg cttaagcaat tggcagccag agacataaac
     9361 acggggtaat aagaataaac aggaggaaag gtgaaaagaa acgataaaat cctccattac
     9421 agaggattaa attgataata aatcggctga atcccacaac ttacagcaat ttctctattt
     9481 ttttaattaa tcctaaaata gagagcccac acattcagaa taaaattcta cattcaataa
     9541 aaaatgcaga ataaaccaga cattcatgtc tgacctattc tgcaatcagt tagcgtttgc
     9601 aaattgagac taattgctct tccatccact gatggccttt atcgcgcccg gcagcttcat
     9661 gccaggagag ataacaggtt ctgctgtttt gttttaacgg cagcggtaat acctgtaatt
     9721 ctaaggattc agcgaactct tcagccagcc aacgcggcgc aatagcgacc aaatgcgttt
     9781 gcgacaccac gctaagtacg ctcatcattg ccatgccctg atacgcgata ctggcttgct
     9841 tatctaccgt gtcataccaa ggttgactaa atgacgcgaa acgatcgagc gaaaccgccg
     9901 catgttgttc gttataaaca tcatgtttca gtaacgggcc cttaattgtt ggatgatttt
     9961 tgctggctac cagcaccatt tcatctttaa ataatggtac gctggtaaat tcaggacgat
    10021 ggaagtcttc ataactaatc acaaactccg tttcctgata acgcagctga tgttcagtgt
    10081 tctgatttaa tgaagacttg aacataacat gtatatttgg cgcaatctgc tcaatgtgat
    10141 tataaatctg cgaggtcaga atgctgtcta acgggctgca aacacaaaga tgaaatacac
    10201 gttcactgct cgcgggttca aaacctgaac caggcaattc attttgtact agttgcaatg
    10261 cctgacgaac tgaaccaaaa agttgaaatg cgcgagcagt cggttgaata ccacggccat
    10321 aacgaacaaa aagctcgtca ttaaacatca ccttcaggcg tgcaacagcg ttactgaccg
    10381 caggttgcga cattcccaga acatgagcgg cacgagtaat gttttgctcc tgcatcacgg
    10441 catcgaaaac ggttaataag ttgagatcga ccatgcgtag ctgtggtttg cttaactccg
    10501 ccgtctctgg atgatctgtt tgtacctctg gcatacttaa ctccactgtc acacttaact
    10561 ccctttccct tattggaatg cagagaaata atcctgaaga atatgattta tcatgcatat
    10621 aaaataagaa aaagcaaaat gagtaaaatt cggaaaacat aaagatacgg gttctgataa
    10681 aaacagaatc cattgccgtg gaatgagtca tttaccacag cataataatc cataatgttt
    10741 ttgttgcgaa aacaatctaa tcataactac cgcgaatact caatcatcta caaaatggat
    10801 taaatgtgct tatttaataa ttaatttata tatttaatgc attaattctt aacattaatt
    10861 gatcaataat attcaccaaa tcaatatcaa aaaaaatcgc aaaacatata attcaataca
    10921 aatcatcagg ataggttttg caacgcgtgc attttgtccc ctttttcctc gttgattaga
    10981 tgcaaaaatt tatgctgaaa tatgtcaacc gatgaaaagc gtcggtagtt aagcagaaat
    11041 taatatcgct tactttaacc accgcagcac aattagctaa ttttacggat gcagaactca
    11101 cgctggcggg acgtttttat tgcgtcaggg ttgacatccg tttttgtatc cagtaactct
    11161 aaaagcatat cgcattcatc tggagctgat ttaatgactc acatcgttcg ctttatcggt
    11221 ctactactac taaacgcatc ttctttgcgc ggtagacgag tgagcggcat ccagcattaa
    11281 gccagcacgc agtcaaacaa aaaacccgcg ccattgcgcg ggttttttta tgcccgaagc
    11341 gaggcgctct aaaagagaca aggacccaaa ccatgagcca gcaagtcatt attttcgata
    11401 ccacattgcg cgacggtgaa caggcgttac aggcaagctt gagtgtgaaa gaaaaactgc
    11461 aaattgcgct ggcccttgag cgtatgggtg ttgacgtgat ggaagtcggt ttccccgtct
    11521 cttcgccggg cgattttgaa tcggtgcaaa ccatcgcccg ccaggttaaa aacagccgcg
    11581 tatgtgcgtt agctcgctgc gtggaaaaag atatcgacgt ggcggccgaa tccctgaaag
    11641 tcgccgaagc cttccgtatt cataccttta ttgccacttc gccaatgcac atcgccacca
    11701 agctgcgcag cacgctggac gaggtgatcg aacgcgctat ctatatggtg aaacgcgccc
    11761 gtaattacac cgatgatgtt gaattttctt gcgaagatgc cgggcgtaca cccattgccg
    11821 atctggcgcg agtggtcgaa gcggcgatta atgccggtgc caccaccatc aacattccgg
    11881 acaccgtggg ctacaccatg ccgtttgagt tcgccggaat catcagcggc ctgtatgaac
    11941 gcgtgcctaa catcgacaaa gccattatct ccgtacatac ccacgacgat ttgggcctgg
    12001 cggtcggaaa ctcactggcg gcggtacatg ccggtgcacg ccaggtggaa ggcgcaatga
    12061 acgggatcgg cgagcgtgcc ggaaactgtt ccctggaaga agtcatcatg gcgatcaaag
    12121 ttcgtaagga tattctcaac gtccacaccg ccattaatca ccaggagata tggcgcacca
    12181 gccagttagt tagccagatt tgtaatatgc cgatcccggc aaacaaagcc attgttggca
    12241 gcggcgcatt cgcacactcc tccggtatac accaggatgg cgtgctgaaa aaccgcgaaa
    12301 actacgaaat catgacacca gaatctattg gtctgaacca aatccagctg aatctgacct
    12361 ctcgttcggg gcgtgcggcg gtgaaacatc gcatggatga gatggggtat aaagaaagtg
    12421 aatataattt agacaatttg tacgatgctt tcctgaagct ggcggacaaa aaaggtcagg
    12481 tgtttgatta cgatctggag gcgctggcct tcatcggtaa gcagcaagaa gagccggagc
    12541 atttccgtct ggattacttc agcgtgcagt ctggctctaa cgatatcgcc accgccgccg
    12601 tcaaactggc ctgtggcgaa gaagtcaaag cagaagccgc caacggtaac ggtccggtcg
    12661 atgccgtcta tcaggcaatt aaccgcatca ctgaatataa cgtcgaactg gtgaaataca
    12721 gcctgaccgc caaaggccac ggtaaagatg cgctgggtca ggtggatatc gtcgctaact
    12781 acaacggtcg ccgcttccac ggcgtcggcc tggctaccga tattgtcgag tcatctgcca
    12841 aagccatggt gcacgttctg aacaatatct ggcgtgccgc agaagtcgaa aaagagttgc
    12901 aacgcaaagc tcaacacaac gaaaacaaca aggaaaccgt gtgatgtcga agaattacca
    12961 tattgccgta ttgccggggg acggtattgg tccggaagtg atgacccagg cgctgaaagt
    13021 gctggatgcc gtgcgcaacc gctttgcgat gcgcatcacc accagccatt acgatgtagg
    13081 cggcgcagcc attgataacc acgggcaacc actgccgcct gcgacggttg aaggttgtga
    13141 gcaagccgat gccgtgctgt ttggctcggt aggcggcccg aagtgggaac atttaccacc
    13201 agaccagcaa ccagaacgcg gcgcgctgct gcctctgcgt aagcacttca aattattcag
    13261 caacctgcgc ccggcaaaac tgtatcaggg gctggaagca ttctgtccgc tgcgtgcaga
    13321 cattgccgca aacggcttcg acatcctgtg tgtgcgcgaa ctgaccggcg gcatctattt
    13381 cggtcagcca aaaggccgcg aaggtagcgg acaatatgaa aaagcctttg ataccgaggt
    13441 gtatcaccgt tttgagatcg aacgtatcgc ccgcatcgcg tttgaatctg ctcgcaagcg
    13501 tcgccacaaa gtgacgtcga tcgataaagc caacgtgctg caatcctcta ttttatggcg
    13561 ggagatcgtt aacgagatcg ccacggaata cccggatgtc gaactggcgc atatgtacat
    13621 cgacaacgcc accatgcagc tgattaaaga tccatcacag tttgacgttc tgctgtgctc
    13681 caacctgttt ggcgacattc tgtctgacga gtgcgcaatg atcactggct cgatggggat
    13741 gttgccttcc gccagcctga acgagcaagg ttttggactg tatgaaccgg cgggcggctc
    13801 ggcaccagat atcgcaggca aaaacatcgc caacccgatt gcacaaatcc tttcgctggc
    13861 actgctgctg cgttacagcc tggatgccga tgatgcggct tgcgccattg aacgcgccat
    13921 taaccgcgca ttagaagaag gcattcgcac cggggattta gcccgtggcg ctgccgccgt
    13981 tagtaccgat gaaatgggcg atatcattgc ccgctatgta gcagaagggg tgtaatcatg
    14041 gctaagacgt tatacgaaaa attgttcgac gctcacgttg tgtacgaagc cgaaaacgaa
    14101 accccactgt tatatatcga ccgccacctg gtgcatgaag tgacctcacc gcaggcgttc
    14161 gatggtctgc gcgcccacgg tcgcccggta cgtcagccgg gcaaaacctt cgctaccatg
    14221 gatcacaacg tctctaccca gaccaaagac attaatgcct gcggtgaaat ggcgcgtatc
    14281 cagatgcagg aactgatcaa aaactgcaaa gaatttggcg tcgaactgta tgacctgaat
    14341 cacccgtatc aggggatcgt ccacgtaatg gggccggaac agggcgtcac cttgccgggg
    14401 atgaccattg tctgcggcga ctcgcatacc gccacccacg gcgcgtttgg cgcactggcc
    14461 tttggtatcg gcacttccga agttgaacac gtactggcaa cgcaaaccct gaaacagggc
    14521 cgcgcaaaaa ccatgaaaat tgaagtccag ggcaaagccg cgccgggtat taccgcaaaa
    14581 gatatcgtgc tggcaattat cggtaaaacc ggtagcgcag gcggcaccgg gcatgtggtg
    14641 gagttttgcg gcgaagcaat ccgtgattta agcatggaag gtcgtatgac cctgtgcaat
    14701 atggcaatcg aaatgggcgc aaaagccggt ctggttgcac cggacgaaac cacctttaac
    14761 tatgtcaaag gccgtctgca tgcgccgaaa ggcaaagatt tcgacgacgc cgttgcctac
    14821 tggaaaaccc tgcaaaccga cgaaggcgca actttcgata ccgttgtcac tctgcaagca
    14881 gaagaaattt caccgcaggt cacctggggc accaatcccg gccaggtgat ttccgtgaac
    14941 gacaatattc ccgatccggc ttcgtttgcc gatccggttg aacgcgcgtc ggcagaaaaa
    15001 gcgctggcct atatggggct gaaac
//
LOCUS       DACAOP010000103        14529 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.103, whole genome shotgun sequence.
ACCESSION   DACAOP010000103 DACAOP010000000
VERSION     DACAOP010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14529
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.103"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            47..370
                     /gene="iraM"
                     /locus_tag="IT892_003648"
     CDS             47..370
                     /gene="iraM"
                     /locus_tag="IT892_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HAP3136812.1"
                     /translation="MKWIVIDTVIQPTCGISFSAIWGNMKMIIWYQSTIFLPPGSIFT
                     PVKSGIILKDKEYPITIYHIAPFNKDLWSLLKSSQECPPGESKITNKCLHNSCIIKIC
                     PYGLK"
     gene            complement(473..1723)
                     /gene="icd"
                     /locus_tag="IT892_003649"
     CDS             complement(473..1723)
                     /gene="icd"
                     /locus_tag="IT892_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HAP3136813.1"
                     /translation="MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPA
                     MLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGP
                     LTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
                     AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAI
                     ANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIV
                     IKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL
                     FEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYD
                     FERLMEGAKLLKCSEFGEAIIENM"
     gene            1895..2548
                     /gene="rluE"
                     /locus_tag="IT892_003650"
     CDS             1895..2548
                     /gene="rluE"
                     /locus_tag="IT892_003650"
                     /EC_number="5.4.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415653.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2457) synthase RluE"
                     /protein_id="HAP3136814.1"
                     /translation="MRQFIISENTMQKTSFRNHQVKRFSSQRSTRRKPENQPTRVILF
                     NKPYDILPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPG
                     KRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER
                     KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWREVTD"
     gene            2558..3019
                     /gene="nudJ"
                     /locus_tag="IT892_003651"
     CDS             2558..3019
                     /gene="nudJ"
                     /locus_tag="IT892_003651"
                     /EC_number="3.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase NudJ"
                     /protein_id="HAP3136815.1"
                     /translation="MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETL
                     VEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDID
                     CCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI"
     gene            3073..4179
                     /gene="mnmA"
                     /locus_tag="IT892_003652"
     CDS             3073..4179
                     /gene="mnmA"
                     /locus_tag="IT892_003652"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415651.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAP3136816.1"
                     /translation="MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD
                     GEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILC
                     NKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSH
                     EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQP
                     GKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQG
                     HEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFD
                     EPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV"
     gene            4215..4856
                     /gene="hflD"
                     /locus_tag="IT892_003653"
     CDS             4215..4856
                     /gene="hflD"
                     /locus_tag="IT892_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high frequency lysogenization protein HflD"
                     /protein_id="HAP3136817.1"
                     /translation="MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSII
                     DMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSA
                     KGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQS
                     PQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL"
     gene            4860..6230
                     /gene="purB"
                     /locus_tag="IT892_003654"
     CDS             4860..6230
                     /gene="purB"
                     /locus_tag="IT892_003654"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAP3136818.1"
                     /translation="MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWL
                     QKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKE
                     KVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQ
                     YRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHI
                     AAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVW
                     GYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQ
                     RDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTV
                     MRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAIT
                     MVDELK"
     gene            6399..7070
                     /gene="phoP"
                     /locus_tag="IT892_003655"
     CDS             6399..7070
                     /gene="phoP"
                     /locus_tag="IT892_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PhoP"
                     /protein_id="HAP3136819.1"
                     /translation="MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHI
                     PDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKP
                     FHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMET
                     LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGY
                     LFELR"
     gene            7070..8530
                     /gene="phoQ"
                     /locus_tag="IT892_003656"
     CDS             7070..8530
                     /gene="phoQ"
                     /locus_tag="IT892_003656"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoQ"
                     /protein_id="HAP3136820.1"
                     /translation="MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSF
                     DKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDV
                     PWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVA
                     VNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSL
                     RPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLT
                     HSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMRGGTLLS
                     RELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACK
                     YCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAR
                     EITEQYEGKIVAGESMLGGARMEVIFGRQHSAPKDE"
     gene            8606..9727
                     /locus_tag="IT892_003657"
     CDS             8606..9727
                     /locus_tag="IT892_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415646.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAP3136821.1"
                     /translation="MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLA
                     MESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRE
                     LPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLL
                     QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYV
                     LQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSR
                     HELDIAPPEPPYQPDEIYDALKQGEVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALD
                     ALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG"
     gene            complement(9776..11002)
                     /gene="pepT"
                     /locus_tag="IT892_003658"
     CDS             complement(9776..11002)
                     /gene="pepT"
                     /locus_tag="IT892_003658"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAP3136822.1"
                     /translation="MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEE
                     MGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGD
                     IALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKKI
                     PHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIV
                     GNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMH
                     YIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILD
                     IAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEK
                     AVQVIVRIAELTAQRK"
     gene            11252..12388
                     /gene="potA"
                     /locus_tag="IT892_003659"
     CDS             11252..12388
                     /gene="potA"
                     /locus_tag="IT892_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein PotA"
                     /protein_id="HAP3136823.1"
                     /translation="MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGE
                     FLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFP
                     HMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIAR
                     AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRI
                     VVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGREC
                     NIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELE
                     NGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK"
     gene            12372..13235
                     /gene="potB"
                     /locus_tag="IT892_003660"
     CDS             12372..13235
                     /gene="potB"
                     /locus_tag="IT892_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309597.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotB"
                     /protein_id="HAP3136824.1"
                     /translation="MKNTSKFQNVVIVTIVGWLVLFVFLPNLMIIGTSFLTRDDASFV
                     KMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLL
                     FLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYI
                     LLPFMVMPLYSSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPA
                     MGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLVYWRASR
                     LLNKKVSELDD"
     gene            complement(13468..13733)
                     /locus_tag="IT892_003661"
                     /pseudo
     CDS             complement(13468..13733)
                     /locus_tag="IT892_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387760.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            13790..14458
                     /locus_tag="IT892_003662"
     CDS             13790..14458
                     /locus_tag="IT892_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP3136825.1"
                     /translation="MVKSMKKNTDHGAKIYTPLTLKLYDWWVLGVSNRLAWGCPTKEH
                     LLPHFLEHLGNNHLDIGVGTGFYLTHVPESSLISLMDLNEASLNAASTRAGESKIKHK
                     ISHDVFEPYPAALHGQFDSISMFYLLHCLPGNISTKSCVIRNAAQALTDDGTLYGATI
                     LGDGVVHNSFGQKLMRIYNQKGIFSNTKDSEEGLTHILSEHFENVKTKVQGTVVMFSA
                     SGKK"
BASE COUNT         3634 a         3652 c         3568 g         3675 t
ORIGIN      
        1 acatcctaat gaaccatatt aaataccgtg ggataagaca taacaaatga agtggatagt
       61 aattgacacg gtaattcaac ctacatgtgg tatatctttt tcagccatat ggggtaatat
      121 gaaaatgatc atctggtatc aatctactat atttctccct cctggcagta tatttacacc
      181 ggttaagtct ggtattatcc ttaaggataa agaatatcct attactattt atcacatcgc
      241 accattcaac aaggatttat ggagtttact caaaagcagt caagagtgtc ctccaggaga
      301 aagcaaaata acaaataaat gtttacataa tagttgcatt ataaaaatat gcccatatgg
      361 gctcaagtaa tgggcttcat ataaatatgc tcgatatgct attaataata tccacataaa
      421 taaaacaacg ggcgtgttat acgcccgttt caatatttaa cacatggaga gattacatgt
      481 tttcgatgat cgcttcacca aactctgaac atttcagcag cttagcgcct tccatcagac
      541 gttcgaagtc ataagttacg gtcttggcat tgattgcgcc ttccatacct ttaacaatca
      601 ggtcagccgc ttcagtccaa cccatatggc gcagcatcat ctcagcggag agaataatag
      661 agccaggatt tactttgtcc tgaccggcat atttcggcgc agtaccgtgg gtggcttcaa
      721 acagggcgca ttcgtcaccg atgtttgcac caggggcgat accgataccg ccaacctgcg
      781 ctgccagggc gtcagaaatg tagtcaccgt tcaggttcat acaggcgata acatcatatt
      841 cagccggacg cagcaggatc tgttgcagga atgcatcagc aatcacgtct ttaatgacga
      901 tctctttgcc agtgttcggg tttttaactt tcagccacgg gccaccgtcg atcagttcac
      961 cgccaaactc ttcacgcgcc agctggtagc cccagtcttt aaacgctcct tcggtgaact
     1021 tcatgatgtt gcctttgtgc accagagtca cagagtcacg atcgttagca attgcgtatt
     1081 cgatcgctgc acgaaccaga cgtttggtgc cttcttccga acacggctta ataccgatac
     1141 cacaatgttc cgggaagcga attttcttca cccccatctc ttcacgcagg aatttaatca
     1201 ctttctcggc gtcggcagag tctgctttcc attcgatacc cgcataaatg tcttccgagt
     1261 tttcacggaa gataaccata tcggtcagtt cagggtgttt aaccgggctt ggagtgccct
     1321 gatagtaacg taccggacgc aggcagatgt agagatccag ttcctggcgc agggcaacgt
     1381 tcagagagcg aataccgcca ccaaccggag tggtcagcgg acctttaatg gcaacgcgat
     1441 attcacgaat cagatcaaga gtttcagcag gcagccagac gtcctgacca taaacctgtg
     1501 tggatttttc accggtgtaa atttccatcc aggagatttt acgctcgcct ttataggctt
     1561 tctcgactgc agcgtcgacc actttcagca tggctggggt tacatctaca ccgattccat
     1621 caccttcaat gtaagggata atcggatttt caggaacgtt gagtttgccg ttttgcaggg
     1681 tgatcttctt gccttgtgcc ggaacaacta ctttactttc cattcacctc tccttcgagc
     1741 gctactggtt tgctcgtctg ccaccacgtt gcatatgcgt ttgcgtcctg cgatacggat
     1801 gctttagagc aattttttgt taatgatttg taattggctt gtcaatacta ccctattgtt
     1861 tgccgtcatg aaagatgcgc gttattaggc tataatgcgg caattcataa tctctgaaaa
     1921 taccatgcaa aaaacttctt ttagaaatca ccaggttaag cgattcagct cgcaacgttc
     1981 taccaggcgt aaacctgaaa accagcccac gcgtgtgatc ctgttcaata aaccctacga
     2041 tattcttccg cagttcaccg atgaagccgg acgcaaaaca ttaaaagaat tcatcccggt
     2101 tcagggtgtt tatgcagcag gtcgccttga ccgcgatagc gaagggttgc tggtgctgac
     2161 caataacggc gcgttgcagg cgcgtttaac ccagccgggt aaacgcaccg gaaaaatcta
     2221 ttatgtgcag gtggaaggta ttcccacaca agacgcactt gaagccttgc gcaatggcgt
     2281 aaccttaaat gatggcccta ccctgcccgc cggcgcggag ctggttgacg aacccgcgtg
     2341 gttatggccg cggaatccac caattcgtga acgcaaaagt attcccacca gctggctgaa
     2401 gatcacctta tatgaaggac gtaatcgcca ggtgcgccgc atgaccgccc atgttggctt
     2461 ccccacgctg cgactgattc gctatgcgat gggtgattac tctttggata atcttgccaa
     2521 tggtgaatgg cgagaagtga cagattaagg atgcaaaatg tttaaaccgc acgttaccgt
     2581 tgcttgcgtg gtgcacgcag aaggcaaatt tttagtcgtt gaagagacga ttaatggtaa
     2641 agcgttatgg aaccaacctg ccgggcatct ggaagccgat gaaaccttag tggaagccgc
     2701 cgcccgtgaa ctgtgggaag aaaccggcat cagcgcgcag ccgcaacact ttattcgtat
     2761 gcatcagtgg attgcgccag ataaaacgcc gtttttgcgt ttcctctttg ccattgagct
     2821 tgagcaaata tgcccgaccc agcctcatga cagcgatatc gactgctgcc gttgggtcag
     2881 cgccgaagaa attttacagg cgtcaaatct tcgttcgccg ctggtggcgg aaagtattcg
     2941 ttgttatcaa agcgggcaac gttatccgct ggagatgatt ggcgatttta actggccttt
     3001 tacaaagggt gtcatctaaa aggctgcgtg atagaatacg ccgccttgaa gttcaatgtc
     3061 gtgagtgatc caatgtctga aaccgcaaaa aaagtaatcg tcggcatgtc cggcggtgtc
     3121 gattcctccg tttctgcctg gctgttgcaa caacagggat atcaggtcga aggcctgttt
     3181 atgaagaact gggaagaaga cgacggtgag gaatattgca cagcggcagc ggatctggct
     3241 gatgcccagg ctgtctgcga caagctcggc attgaactgc acaccgttaa ctttgctgcc
     3301 gagtactggg acaacgtctt cgaactgttc cttgccgaat ataaagccgg tcgcacgccg
     3361 aatccggata ttctgtgcaa caaagagatc aaatttaaag ccttcctcga atttgccgcc
     3421 gaagatttag gtgccgatta tatcgctacc ggtcattacg tacgtcgggc cgatgtcgat
     3481 ggcaagagcc gcctgctgcg tggtctggac agcaataaag accagagcta cttcctttat
     3541 acgctcagcc atgagcagat tgcgcaaagc ctgttcccgg tcggcgaact ggaaaaaccg
     3601 caggtgcgta agattgctga agatcttggt ctggtcaccg cgaagaaaaa agactctacc
     3661 ggcatttgct tcattggcga acgtaaattc cgcgagttcc tgggccgtta tctcccggcg
     3721 caaccgggca aaatcattac cgtcgatggc gatgaaattg gtgagcacca ggggctgatg
     3781 tatcacactc tcggtcagcg taaaggtctg ggtatcggtg gcaccaaaga aggtaccgaa
     3841 gaaccgtggt atgtggtgga caaagacgtc gaaaacaaca ttctggttgt cgctcagggc
     3901 catgaacacc cgcggctgat gtctgtcggg ttgattgccc agcagttgca ctgggtcgat
     3961 cgcgaaccat tcaccggcac tatgcgttgc acggtaaaaa cccgctatcg ccagaccgat
     4021 atcccttgca ccgtcaaggc gctggacgat gatcgcattg aagtgatttt cgatgaaccg
     4081 gttgccgccg tgacgccggg ccagtctgcc gtcttctata acggtgaagt gtgcctcggt
     4141 ggcggtatta ttgagcagcg tctgccgctg ccggtctgat tattatcttt acttaaaaca
     4201 aggaagcagt gaacgtggca aagaattact atgacatcac cctcgccctg gccggtattt
     4261 gtcagtcggc acgcctggtg caacaactcg ctcaccaggg gcattgtgat gccgatgcgc
     4321 tacacgtctc actcaacagt attattgata tgaaccccag ctcgacgctg gcggtttttg
     4381 gcggtagcga agccaacctg cgcgtcgggc tggaaaccct gctcggcgtg ctcaatgcca
     4441 gcagtcgcca gggcttaaac gccgaattaa cccgctacac actcagcttg atggtgcttg
     4501 agcgcaaact ctcctcagcg aaaggcgcgc tcgacactct gggcaaccgg atcaacggcc
     4561 tgcaacgcca gctcgaacac ttcgatttac agtccgaaac gctgatgagc gcgatggctg
     4621 ctatctatgt tgatgtgatt agcccgcttg gcccgcgcat tcaggtcacc ggttcccctg
     4681 ctgtactgca aagcccacaa gtgcaggcga aagttcgcgc aaccctgctg gcaggcattc
     4741 gcgccgccgt gctctggcac caggtcggcg gcggacgtct gcaactgatg ttttctcgta
     4801 atcgcctgac cactcaggca aaacaaattc ttgctcattt aaccccggag ttgtgatcta
     4861 tggaattatc ctcactgacc gccgtttccc ctgtcgatgg acgctacggc gataaagtca
     4921 gcgcgctgcg cgggattttc agcgaatatg gtttgctgaa attccgtgta caagttgaag
     4981 tacgttggct gcaaaaactg gccgcgcacg cagcgatcaa ggaagttcct gcttttgctg
     5041 ccgacgcaat cggttacctt gatgcaatcg tcgccagttt cagcgaagaa gatgcggcgc
     5101 gcatcaaaac tatcgagcgt accactaacc acgacgttaa agcggttgag tatttcctga
     5161 aagaaaaagt ggcggagatc ccggaactgc acgcggtttc tgaattcatc cactttgcct
     5221 gtacttcgga agatatcaat aacctctccc acgcattaat gctgaaaacc gcgcgtgatg
     5281 aagtgatcct gccatactgg cgtcaactga ttgatggcat taaagatctc gccgttcagt
     5341 atcgcgatat cccgctgctg tctcgtaccc acggtcagcc agccacgccg tcaaccatcg
     5401 gtaaagagat ggcaaacgtc gcctaccgta tggagcgcca gtaccgccag cttaaccagg
     5461 tggagatcct cggcaaaatc aacggcgcgg tcggtaacta taacgcccac atcgccgctt
     5521 acccggaagt tgactggcat cagttcagcg aagagttcgt cacctcgctg ggtattcagt
     5581 ggaacccgta caccacccag atcgaaccgc acgactacat tgccgaactg tttgattgcg
     5641 ttgcgcgctt caacactatt ctgatcgact ttgaccgtga cgtctggggt tatatcgccc
     5701 ttaaccactt caaacagaaa accattgctg gtgagattgg ttcttccacc atgccgcata
     5761 aagttaaccc gatcgacttc gaaaactccg aagggaatct gggcctttcc aacgcggtat
     5821 tgcagcatct ggcaagcaaa ctgccggttt cccgctggca gcgtgacctg accgactcta
     5881 ccgtgctgcg taacctcggc gtgggtatcg gttatgcctt gattgcatat caatccaccc
     5941 tgaaaggcgt gagcaaactg gaagtgaacc gtgaccatct gctggatgaa ctggatcaca
     6001 actgggaagt gctggctgaa ccaatccaga cagttatgcg tcgctatggc atcgaaaaac
     6061 cgtacgagaa gctgaaagag ctgactcgcg gtaagcgcgt tgacgccgaa ggcatgaagc
     6121 agtttatcga tggtctggcg ttgccagaag aagagaaagc ccgcctgaaa gcgatgacgc
     6181 cggctaacta tattggtcga gctatcacga tggttgatga gctgaaataa acctcgtatc
     6241 agtgccggat ggcgatgctg tccggcctgc ttattaagat tatccgcttt ttattttttc
     6301 actttacctc ccctccccgc tggtttattt aatgtttacc cccataacca cataatcgcg
     6361 ttacactatt ttaataatta agacagggag aaataaaaat gcgcgtactg gttgttgaag
     6421 acaatgcgtt gttacgtcac caccttaaag ttcagattca ggatgctggt catcaggtcg
     6481 atgacgcaga agatgccaaa gaagccgatt attatctcaa tgaacatata ccggatattg
     6541 cgattgtcga tctcggattg ccagacgagg acggtctgtc actgattcgc cgctggcgta
     6601 gcaacgatgt ttcactgccg attctggtat taaccgcccg tgaaagctgg caggacaaag
     6661 tcgaagtatt aagtgccggt gctgatgatt atgtgactaa accgtttcat attgaagagg
     6721 tgatggcgcg aatgcaggca ttaatgcggc gtaatagcgg tctggcttca caggtcattt
     6781 cgctcccccc gtttcaggtt gatctctctc gccgtgaatt atctattaat gacgaagtga
     6841 tcaaactgac cgcgttcgaa tacaccatta tggaaacgtt gatacgcaat aatggcaaag
     6901 tggtcagcaa agattcgtta atgctccaac tctatccgga tgcggagctg cgggaaagcc
     6961 ataccattga tgtactgatg ggacgtctgc gcaaaaaaat tcaggcacaa tatccccaag
     7021 aagtgattac caccgttcgc ggccagggct atctgttcga attgcgctga tgaaaaaatt
     7081 actgcgtctt tttttcccgc tctcgctgcg ggtacgtttt ctgttggcaa cggcagcggt
     7141 agtactggtg ctttcgcttg cctacggaat ggtcgcgctg atcggttata gcgtcagttt
     7201 cgataaaact acgtttcggc tgttacgtgg cgagagcaat ctgttctata cccttgcgaa
     7261 gtgggaaaac aataagttgc atgtcgagtt acccgaaaat atcgacaagc aaagccccac
     7321 catgacgcta atttatgatg agaacgggca gcttttatgg gcgcaacgtg acgtgccctg
     7381 gctgatgaag atgatccagc ctgactggct gaaatcgaat ggttttcatg aaattgaagc
     7441 ggatgttaac gataccagcc tcttgctgag tggagatcat tcgatacagc aacagttgca
     7501 ggaagtgcgg gaagatgatg acgacgcgga gatgacccac tcggtggcag taaacgtcta
     7561 cccggcaaca tcgcggatgc caaaattaac cattgtggtg gtggatacca ttccggtgga
     7621 gctaaaaagt tcctatatgg tctggagctg gtttatctat gtgctctcag ccaatctgct
     7681 gttagtgatc ccgctgctgt gggtcgccgc ctggtggagt ttacgcccca tcgaagccct
     7741 ggcaaaagaa gtccgcgaac tggaagaaca taaccgcgaa ttgctcaatc cagccacaac
     7801 gcgagaactg accagtctgg tacgaaacct gaaccgattg ttaaaaagtg aacgcgaacg
     7861 ttacgacaaa taccgtacga cgctcaccga cctgacccat agtctgaaaa cgccactggc
     7921 ggtgctgcaa agtacgctgc gttctctgcg tagtgaaaag atgagcgtca gtgatgctga
     7981 gccggtaatg ctggagcaaa tcagccgcat ttcacagcaa attggctact acctgcatcg
     8041 tgccagtatg cgcggcggga cattgctcag ccgcgagctg catccggtcg ccccactgct
     8101 ggacaatctc acctcagcgc tgaacaaagt gtatcaacgc aaaggggtca atatctctct
     8161 cgatatttcg ccagagatca gctttgtcgg tgagcagaac gattttgtcg aggtgatggg
     8221 caacgtgctg gataatgcct gtaaatattg cctcgagttt gtcgaaattt ctgcaaggca
     8281 aaccgacgag catctctata ttgtggtcga ggatgatggc cccggtattc cattaagcaa
     8341 gcgagaggtc attttcgacc gtggtcaacg ggttgatact ttacgccctg ggcaaggtgt
     8401 agggctggcg gtagcccgcg aaatcaccga gcaatatgag ggtaaaatcg tcgccggaga
     8461 gagcatgctg ggcggtgcgc ggatggaggt gatttttggt cgccagcatt ctgcgccgaa
     8521 agatgaataa atatgcccat acttcacgca ttacgttaag catccgttat aatcggttgc
     8581 agataccagc ctgtggatgc ttaacatgga ataccaactc actcttaact ggcccgattt
     8641 tcttgaacgt cactggcaga aacgcccggt ggtgttaaaa cgcggcttta ataattttat
     8701 tgacccgatc tctccagacg agttggcggg tctggcgatg gaaagcgaag ttgacagtcg
     8761 actggtcagt caccaggatg gcaaatggca ggtcagccac ggcccgttcg aaagctacga
     8821 tcatctcggt gaaaccaact ggtcattact ggtacaggca gtgaaccact ggcatgagcc
     8881 gaccgccgcg ctgatgcgac cgttccgtga actaccggac tggcgtattg atgatctgat
     8941 gatttctttt tctgtacccg gcggcggcgt cggcccgcat ctcgatcagt acgacgtgtt
     9001 tatcattcag ggtaccggac gtcgtcgctg gcgagtgggc gaaaagctgc aaatgaaaca
     9061 gcactgccca catccggatc tgttacaggt cgatccgttc gaagccatca tcgatgaaga
     9121 gctggagcct ggtgatattc tttatattcc gccaggattc ccgcatgaag gctacgcgct
     9181 ggaaaatgcg atgaactatt ccgtgggctt tcgcgcgcca aatacgcggg aactgattag
     9241 tggatttgcc gattatgtgc tgcaacgtga actgggcggc aactactaca gcgatccgga
     9301 tgttccacct cgcgctcatc ctgcggatgt tctgccgcaa gagatggata aactgcgtga
     9361 gatgatgctc gaattgatca accagccgga acactttaag caatggtttg gcgagtttat
     9421 atcccagtca cgtcatgaac tggatatcgc gccgccagag ccgccttatc agccggatga
     9481 aatctacgat gcgctgaaac aaggtgaagt gctggtgcgc ctgggtggtc tgcgcgtatt
     9541 gcgcattggc gacgacgtgt atgccaatgg tgagaagatc gattccccgc accgtccggc
     9601 actggatgca ctcgccagca acattgcgct gactgcggag aattttggcg atgcgctgga
     9661 agatccgtca ttcctcgcga tgctcgcggc gctggtcaat agcgggtatt ggttcttcga
     9721 agggtaagtt tggatttaag ccggatgcgg catcacatgc cgcatccctt ttcgcttact
     9781 tccgttgcgc cgttaactcg gcaatacgga cgatcacctg caccgctttt tccatacctt
     9841 ccagagtcac aaactcatgc ttaccatgat agttgtaacc gccagtgaac aggttcgggc
     9901 acggtaatcc cataaacgac aactgcgcgc cgtcggtacc accgcggatc ggtttcagtt
     9961 ccggttcaat atcgcaatcg cgcatcgcct gctgggcgat atcgagaata tgcggatgct
    10021 caaccacttt ctcgcgcata ttgtagtaac tgtcttcaat caccagttca atgtagcaat
    10081 caggatgtaa ccctttgccc acttttttgg cgatctccat cattttacgt ttacgcgctt
    10141 caaactgttt acggtcgaaa tcacggatga tgtagtgcat atcggcccgt tcaacggtgc
    10201 ctttcatgct cgccagatga tagaaacctt catagccttc tgtcatttcc gggctttcat
    10261 ccgccggaac ttccgcatga atacgtgccg ccagcgacag cgcatttacc atcactcctt
    10321 tcgccgtgcc cggatgaaca ttgttaccga caattttgat attgaccgac gcggcgttga
    10381 agttttcaaa ctccagttcg cctacgccac caccatcaac agtgtaagcc cagcgggcat
    10441 cgaaggcgtc aacatcaaaa tgtttcgccc ctttgcccac ttcttcatcc ggggtaaagg
    10501 cgacgcgaat atcaccatgc ggaatttttt tctgttgcaa taccgccagc gcggtcatga
    10561 tttctgcaat acctgctttg tcatcggcac ctaacaaggt tttaccatcg gtggtaatca
    10621 gcgtctgacc cagtagctga tgcagcaccg ggaacataac cggtgataaa acttcatcgc
    10681 cgatacccag cgcaatatcg ccaccgcgat agttttcaac aatttgcgga ttcacatttt
    10741 tgccgctgca atccggtgag gtatccacat gagaaataaa gccaatcgcc gggatatcgc
    10801 cagggacgtt agccggtaac gtcgccatca aagtgccctt ctcacttaag gtcacattga
    10861 taagccccat ctcttcgagc tgctctttca gcagatgcaa taacttccat tggccttccg
    10921 tgctgggaac ctgtctcacc cctgcttttg attgggtatc cagagacacg tagttcaaaa
    10981 atcgctcaag tagtttatcc atgtagtcac cctcactttt tgtgacaaca ttattaagaa
    11041 gcaagaaaag acaaatattg cgtcaggtca cttttacccc tgcaagcggg aatatttatc
    11101 agcattacct taatgaatat aaagctaagc cagtaattca caacaaagat tggcgattca
    11161 agcggtttgc cgtagaatta ccgccctcat taagagtcac caaggtggtt aaccacaaac
    11221 cccgcatcgg taagccatcc gttgcgttta catgggacag agtaaaaaat tgaataaaca
    11281 accgagttcg ctttcaccgc tggtgcaatt ggcgggaatt cgcaaatgct ttgatggtaa
    11341 agaggtcatt ccccagctgg atctgactat caacaatggc gagttcctca cgctgcttgg
    11401 cccttctggc tgcggtaaaa caaccgttct tcgcctgatt gcaggtctgg aaactgttga
    11461 ttccggacgc atcatgctgg ataacgagga catcacccac gttccggcgg aaaaccgcta
    11521 tgtgaacact gttttccaaa gctacgcact tttcccccac atgaccgtgt tcgaaaatgt
    11581 ggcctttggg ttgcgcatgc aaaaaacccc cgctgctgaa attacgcccc gcgtgatgga
    11641 agccctgcgg atggtgcagt tggaaacctt cgctcaacgc aaaccgcatc agctctctgg
    11701 tggtcaacag caacgcgtcg ccattgctcg cgcggtggtt aacaagcctc gtctgttgtt
    11761 gctggatgag tcgctctcag cgctggatta caaactgcgt aagcaaatgc agaacgagct
    11821 gaaagcgtta cagcgtaagc ttggcattac attcgtcttt gtgactcacg accaggaaga
    11881 agcactcacc atgtcagaca ggattgtggt gatgcgcgat ggtcgcattg agcaagacgg
    11941 cacgccgcgt gaaatctacg aagagccgaa aaacctgttt gttgccggct tcattggcga
    12001 aatcaatatg tttaacgcca ctgtcatcga acgtctagac gagcagcgcg tacgcgccaa
    12061 cgttgaaggc cgcgaatgta atatctacgt taacttcgcc gttgaaccgg ggcaaaaact
    12121 gcatgttctg ctgcgcccgg aagacttacg tgttgaagag attaacgacg acaaccacgc
    12181 tgaagggctg attggttacg ttcgcgagcg taactacaaa ggcatgacgc tggagtcggt
    12241 tgttgaactg gaaaatggca agatggtgat ggtcagcgaa ttcttcaatg aagacgatcc
    12301 tgactttgac cactctctcg accaaaaaat ggccattaat tgggtagaaa gctgggaggt
    12361 cgtactggct gatgaagaac acaagtaagt tccagaatgt agtgattgtc actattgtcg
    12421 gttggcttgt gttgtttgtc tttctgccca acctgatgat cattggcacc agctttttga
    12481 cccgcgacga cgccagtttt gtcaaaatgg tctttacgct ggataactac acgcgtctgc
    12541 tcgatccgct ctattttgaa gtgctattgc actcgctgaa tatggcgctg atcgccaccc
    12601 tcgcctgcct ggtgctgggc tacccgtttg cctggtttct ggcgaagttg ccacacaagg
    12661 tgcgtccgct gctgctgttt ctgctgattg ttccgttctg gaccaactca ttaattcgta
    12721 tctacgggct gaaaattttc ctcagcacca aaggctatct caacgagttt ttgctctggc
    12781 tgggcgttat cgacacacca atccgtatca tgttcacgcc cagtgcggtg attatcggtc
    12841 tggtttacat tctgctgccg tttatggtga tgccgctgta ctccagtatc gaaaaactgg
    12901 ataagccgtt gcttgaggcg gcgcgcgatc tcggtgccag caagttacag acttttatcc
    12961 gtatcattat tccactgacg atgccgggaa ttattgccgg atgtctgctg gtgatgctgc
    13021 cagcgatggg cctgttctat gtatccgacc tgatgggcgg tgcgaaaaac ctgctgatcg
    13081 gtaacgtcat caaggtccag ttccttaata ttcgtgactg gccgtttggt gcagctacca
    13141 gcattacgct gactatcgta atgggcctga tgttgctggt ttactggcgc gcttctcgtt
    13201 tgctgaataa gaaggtgagc gaattagatg attaatcctt tatattcaat gcattaggtt
    13261 tgtttttgag tggttttgcc gtttaaggta acggcattat agatcctatc aaaatcaatc
    13321 aattgcattc tggttttgga gaaagatttt tcgagaactt cggtctttaa ctaaaactga
    13381 ttgcgtataa tcccaatccc ccctccccga ctatctgaat ggtcggggag gcacttcaag
    13441 cacaaaatat catccctgcg ccgttgatta ctctgcaggt gaagtcggcc actcaatatc
    13501 aggtgcagtt gatgtatcaa cacgattcaa caacacccga tatttattcc atgcctccag
    13561 caacgatctt tcttcctccg ttgcgatttc cagatctaca gcatcctgca gtggcgcaat
    13621 atactcactg aattcctgga tgtagaactg tgtggtgacg gtcttccagc cattcggctc
    13681 ctgctgtatc gaagcaacta ggctatttca atatcgctat gctgcggcag catttaaccc
    13741 cttgtaattc atcgccataa ttgatttaat tcacaaataa aactataaca tggtgaaatc
    13801 aatgaaaaaa aacacagatc atggggctaa aatttacaca ccacttaccc taaagcttta
    13861 tgactggtgg gttttgggag tatcaaatcg gcttgcatgg ggatgtccta caaaggaaca
    13921 ccttcttcca cactttctgg aacatttagg taacaaccat ctggatattg gtgttggaac
    13981 tgggttttac cttactcacg tacctgagag tagtctgata tctttaatgg atttgaacga
    14041 agctagcctg aacgcggcat ctacaagggc tggggaatca aaaattaaac ataaaattag
    14101 ccatgatgtt tttgaacctt atcccgcggc gttacatggt caatttgatt ccatttccat
    14161 gttttacctt cttcactgcc tgcctggaaa tatatctaca aaaagctgtg taatacgcaa
    14221 tgcggcgcag gccttaactg acgatggaac tctatacgga gccacaattc ttggcgatgg
    14281 agttgtgcac aatagcttcg gtcaaaaact gatgcgcatt tacaatcaga aaggtatctt
    14341 ttcaaacaca aaagattccg aagaaggctt aacacatata ctctcagagc atttcgagaa
    14401 tgttaaaacc aaggttcaag gtactgtagt aatgttttcc gcttcaggga aaaaatagca
    14461 tccaaccgca gcacgttctt gcttaagacg tgctgcggca taatcccaat gattactccc
    14521 tgacagggt
//
LOCUS       DACAOP010000104        14474 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.104, whole genome shotgun sequence.
ACCESSION   DACAOP010000104 DACAOP010000000
VERSION     DACAOP010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14474
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.104"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..887
                     /locus_tag="IT892_003663"
     CDS             <1..887
                     /locus_tag="IT892_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HAP3136826.1"
                     /translation="EKYYYIQLRGAFLSAIHHQIIENQLDTETITISYEFILCQHLIA
                     NTEFSYLALPENYNRLFLPNSKNQTNNRFKTLNSKAIGRLLAAGGVYNGNIEGFRDTA
                     EKLGGDAIKGYDQILNEKTAGIAIATASILLTKRSNVDTYTEINSYLGKLRGQQKLLD
                     GIDIIEIIYIKRPSKDLANLRKEFNKTVRKNFLIKLAKTSEASGRFNAEDLLRMRKGN
                     VPLNYNVHHKLSLDDGGTNDFENLVLIENEPYHKVFTNMQSRIAKGILVGESKITPWA
                     IPSGSIYPPMKNIMDHTK"
     gene            884..1378
                     /locus_tag="IT892_003664"
     CDS             884..1378
                     /locus_tag="IT892_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001759491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136827.1"
                     /translation="MMTKTQINKLIKMMNDLDYPFEAPLKESFIESIIQIEFNSNSTN
                     CLEKLCNEVSILFKNQPDYLTFLRAMDGFEVNGLRLFSLSIPEPSVKNLFAVNEFYRN
                     NDDFINPDLQERLVIGDYSISIFTYDIKSNFFEIRDNIGTENIFSSFSDFSSFLNEIM
                     DSCS"
     gene            1473..1628
                     /locus_tag="IT892_003665"
     CDS             1473..1628
                     /locus_tag="IT892_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136828.1"
                     /translation="MEKLTTELHSLSEMDRRHVVSILAEIANGYDDFNDMLIYLEFYP
                     NHKILIS"
     gene            1828..2112
                     /locus_tag="IT892_003666"
     CDS             1828..2112
                     /locus_tag="IT892_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136829.1"
                     /translation="MITYHDAFAKANHYLDDADLPVVITLHGRFSQGWYFCFEAREFL
                     ETGDEAARLAGNAPFIIDKDSGEIHSLGTAKPLEEYLQDYEIKKATFGLP"
     gene            complement(2150..3892)
                     /gene="ggt"
                     /locus_tag="IT892_003667"
     CDS             complement(2150..3892)
                     /gene="ggt"
                     /locus_tag="IT892_003667"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HAP3136830.1"
                     /translation="MIKPTFLRRVAIAALLSGSCFSAAAAPPAPPVSYGVEEDVFHPV
                     RAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIR
                     SKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDK
                     YGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKK
                     GDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERT
                     PISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAY
                     ADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYESNQTT
                     HYSVVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGD
                     ANAVGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGLNVAEA
                     TNAPRFHHQWLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYG
                     ASDPRSVDDLTAGY"
     gene            4012..4452
                     /locus_tag="IT892_003668"
                     /pseudo
     CDS             4012..4452
                     /locus_tag="IT892_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417905.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2756 family protein"
     gene            complement(4439..5182)
                     /gene="ugpQ"
                     /locus_tag="IT892_003669"
     CDS             complement(4439..5182)
                     /gene="ugpQ"
                     /locus_tag="IT892_003669"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP3136831.1"
                     /translation="MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKL
                     SKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKMFKGEPLPLLSQVAE
                     RCREHGMMANIEIKPTTGTGPLTGKMVALAARELWAGMTPPLLSSFEIDALEAAQQAA
                     PELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLNKARVMQLKDAGLRILVYTVNKP
                     QRAAELLRWGVDCICTDAIDVIGPNFTAQ"
     gene            complement(5179..6249)
                     /locus_tag="IT892_003670"
     CDS             complement(5179..6249)
                     /locus_tag="IT892_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate import ATP-binding
                     protein UgpC"
                     /protein_id="HAP3136832.1"
                     /translation="MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKS
                     TLLRMVAGLERVTEGDIWINDQRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLK
                     IRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVRDPAVFLFDE
                     PLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGT
                     PVEVYEKPASLFVASFIGSPAMNLLTGRVNNEGTHFELDGGIELPLNGGYRQYAGRKM
                     TLGIRPEHIALSSQAEGGVPMVMDTLEILGADNLAHGRWGEQKLVVRLAHQERPTAGS
                     TLWLHLAENQLHLFDGETGQRV"
     gene            complement(6251..7096)
                     /gene="ugpE"
                     /locus_tag="IT892_003671"
     CDS             complement(6251..7096)
                     /gene="ugpE"
                     /locus_tag="IT892_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpE"
                     /protein_id="HAP3136833.1"
                     /translation="MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQAVYAA
                     PMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAI
                     VWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLQMLDSYAGLTLPLMASATATF
                     LFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWP
                     LLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGL
                     VDSEK"
     gene            complement(7093..7980)
                     /gene="ugpA"
                     /locus_tag="IT892_003672"
     CDS             complement(7093..7980)
                     /gene="ugpA"
                     /locus_tag="IT892_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpA"
                     /protein_id="HAP3136834.1"
                     /translation="MSSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSV
                     DPFGFSSQFVGLDNFVTLFHDSYYLDSFWTTIKFSTFVTVSGLLVSLFFAALVEYIVR
                     GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFL
                     VVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFL
                     LVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFL
                     VIVLTVVQFRYVESKVRYQ"
     gene            complement(8078..9394)
                     /gene="ugpB"
                     /locus_tag="IT892_003673"
     CDS             complement(8078..9394)
                     /gene="ugpB"
                     /locus_tag="IT892_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     substrate-binding protein UgpB"
                     /protein_id="HAP3136835.1"
                     /translation="MKPLHYTASALALGLALMGNAQAVTTIPFWHSMEGELGKEVDSL
                     AQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIK
                     PVYDVFKEAGIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGL
                     DPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDG
                     TDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLAN
                     IREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKP
                     ENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADTATRQMLNKPPLPFTKGLRLGN
                     MPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS"
     gene            complement(9793..10506)
                     /gene="livF"
                     /locus_tag="IT892_003674"
     CDS             complement(9793..10506)
                     /gene="livF"
                     /locus_tag="IT892_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417911.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivF"
                     /protein_id="HAP3136836.1"
                     /translation="MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGK
                     TTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLA
                     MGGFFAERDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSNPRLLL
                     LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLS
                     DTGDALLANEAVRSAYLGG"
     gene            complement(10508..11275)
                     /gene="livG"
                     /locus_tag="IT892_003675"
     CDS             complement(10508..11275)
                     /gene="livG"
                     /locus_tag="IT892_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivG"
                     /protein_id="HAP3136837.1"
                     /translation="MSQPLLSVNGLMMRFGGLLAVNNVNLELYPQEIVSLIGPNGAGK
                     TTVFNCLTGFYKPTGGTILLRDQHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLL
                     VAQHQQLKTGLFSGLLKTPSFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
                     RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVM
                     GISDRIYVVNQGTPLANGTPEQIRNNPDVIRAYLGEA"
     gene            complement(11272..12549)
                     /locus_tag="IT892_003676"
     CDS             complement(11272..12549)
                     /locus_tag="IT892_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivM"
                     /protein_id="HAP3136838.1"
                     /translation="MKPMHIAMALLSAAMFFVLAGVFMGVQLELDGTKLVVDTASDVR
                     WQWVFIGTAVVFFFQLLRPAFHKGLKSVSGPKFILPAIDGSTVKQKLFLVALLVLAVA
                     WPFMVSRGTVDIATLTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
                     GLGFWTCLPIAGLMAAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGG
                     PNGISQIPKPTLFGLEFSRTAREGGWDTFSNFFGLKYDPSDRVIFLYLVALLLVVLSL
                     FVINRLLRMPLGRAWEALREDEIACRSLGLSPRRIKLTAFTISAAFAGFAGTLFAARQ
                     GFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAILLVVSRELMRDFNEYSMLMLGG
                     LMVLMMIWRPQGLLPMTRPQLKLKNGAAKGEQA"
     gene            complement(12546..13472)
                     /gene="livH"
                     /locus_tag="IT892_003677"
     CDS             complement(12546..13472)
                     /gene="livH"
                     /locus_tag="IT892_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivH"
                     /protein_id="HAP3136839.1"
                     /translation="MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHG
                     EVYMIGSYVSFMIIAALMMMGIDTGWLLVAAGFVGAIVIASAYGWSIERVAYRPVRNS
                     KRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWVVGHSENFSASITTMQAVI
                     WIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAV
                     AGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGIAEALSSAYLS
                     TEYKDVVSFALLILVLLVMPTGILGRPEVEKV"
     gene            complement(13520..>14474)
                     /gene="livk"
                     /locus_tag="IT892_003678"
     CDS             complement(13520..>14474)
                     /gene="livk"
                     /locus_tag="IT892_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter substrate-binding protein LivK"
                     /protein_id="HAP3136840.1"
                     /translation="IKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYV
                     IGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLDSSQGPTAAKY
                     ILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARL
                     KKENIDFVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGMLVT
                     MPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKD
                     LKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK"
BASE COUNT         3658 a         3970 c         3534 g         3312 t
ORIGIN      
        1 tggaaaagta ttattatata caactaagag gcgctttttt atcggctatt catcaccaga
       61 tcattgaaaa ccaactggat acagaaacaa taactattag ttatgaattt atcctctgtc
      121 aacatcttat cgcaaatacc gagttcagct atttggcact ccctgaaaat tataaccgtt
      181 tgtttttacc aaattcaaaa aaccaaacaa ataatcgttt caaaacgtta aacagcaaag
      241 ctattggcag gctacttgct gctggtggcg tatacaatgg gaacattgaa ggattcagag
      301 atactgcgga aaaactgggt ggagatgcaa taaaaggcta tgatcaaata ctaaatgaaa
      361 aaacagcggg catagcgata gcaacagcat ctattctttt aacaaagcgt tctaatgttg
      421 atacatatac agaaataaat agttacttag gcaaacttag aggtcaacaa aaacttcttg
      481 atggtataga cataatagaa ataatataca ttaagagacc ttcaaaagac ttagctaact
      541 tacgaaagga gtttaataaa actgtaagaa aaaattttct tatcaaactt gcaaaaacct
      601 ccgaagcatc tggaagattc aacgccgaag accttttaag aatgagaaag ggcaatgttc
      661 ctctaaatta taatgttcac cataaactat ctctagatga tggtggtact aatgatttcg
      721 aaaatttagt attaatcgaa aatgaaccat atcataaagt ttttactaac atgcaatcac
      781 gaatagctaa gggaatatta gtaggtgaaa gcaaaatcac tccctgggcc attccatctg
      841 gctcaattta tcctcccatg aaaaatatta tggaccacac aaaatgatga ctaaaaccca
      901 aataaataaa ttaataaaaa tgatgaatga tttagactat ccatttgaag caccgctcaa
      961 ggaatcattt attgaaagta taatccaaat agaatttaat tctaattcaa ctaattgcct
     1021 ggagaagtta tgtaatgaag ttagtattct ttttaagaat caacctgatt atcttacttt
     1081 tttaagagca atggatggat tcgaagttaa tggattacga ttatttagcc tctcgattcc
     1141 agaaccttca gttaaaaacc tttttgccgt aaatgaattt tatagaaata atgatgattt
     1201 cataaaccct gatctacaag aacggttagt gatcggggat tatagcattt caatatttac
     1261 ttatgacatt aaaagtaact tttttgaaat tagagataat attggcacag aaaatatatt
     1321 cagttcgttt agtgatttct cttcattctt aaacgaaatc atggacagtt gttcataata
     1381 atcaaaagga aacaaaaatc attgtaaacc atgccatctt tttagagatt accagcagaa
     1441 aattccttgt tcgaaattta gcagtgcaag ctatggaaaa acttacaacg gaactacact
     1501 ccttaagtga gatggaccga agacatgtag tctctatttt agccgaaata gctaatggct
     1561 atgatgattt taatgacatg ttgatttatt tagaatttta cccgaatcat aagattctga
     1621 tatcttaaat aagaaaatcc cgttcgacgt tctgaaaaag aaatcataaa atattagcag
     1681 atacttattt cgtgactata tcttatccga tgaacttttt tcaaaaccag catttaataa
     1741 tatctttgac gaagatgaac gcgtctttgc tcaatgtatc acacaggaat aataatataa
     1801 cactcaacaa taatatttat tataattatg attacttatc acgacgcatt cgcgaaagcg
     1861 aaccattacc ttgatgatgc agatctcccg gtcgtcatta ctctacatgg acgctttagc
     1921 cagggctggt atttctgttt cgaagcacga gaatttctcg aaactggaga tgaggccgcg
     1981 cgcttagctg gtaacgcacc ttttattatt gataaagaca gtggtgaaat tcattctctg
     2041 ggaacggcaa aaccgctgga agaatatcta caggattacg aaataaaaaa ggctaccttc
     2101 ggcttgccct gacaaaatag ccctcttccc acgaagaggg ccgctaacct tagtaccccg
     2161 ccgttaaatc atccaccgag cgcgggtcgg atgcgccgta caactcaccg tccggcccaa
     2221 ccataatgct ttgtgtactg cccatcgcct ctttcagcgc cactttctga ccttttgctt
     2281 ccagcagctt gagcgtatcc gggctaaacc ctttttcgac acgcagctcg tccggcaacc
     2341 actgatggtg gaaacgcggc gcattggtcg cttcggcgac gttcaagcca taatcgatgc
     2401 tattcaccac catttgcagc actgtagtga tgatccggct accgcctggg ctaccggtaa
     2461 ccagccaggt tttaccgtct ttcaccacaa tggtcggcga catcgacgac agcgggcgtt
     2521 tgttcggccc gacggcgttg gcatcaccgc ccaccagccc gtaaacgttc ggtacgcccg
     2581 gtttggcgga gaaatcatcc atctggttat taagcagaat accgctctcg cccgcgacaa
     2641 tgcccgtacc gaaggtggtg ttcagcgtat aggtcaccgc caccgcgtta ccatctttat
     2701 ccaccactga gtaatgggta gtttgattac tctcataagg cgcaagcttg ccggggcgaa
     2761 tttcgctgga tggcttcgct ttattgatat caatttgatc ggcaatagat ttggcatagg
     2821 ctttattggt cagcgcctgc cacggtactt tgacaaaatc cgggtcgcca agatattccg
     2881 agcggtcggc gtaggcgtat ttctccgctt ctgccatgat ttgcatcgca tcggcgctgc
     2941 caaagccgta tttcttcata tcgaagtttt ccagaatatt gaggatttgt acgatatgga
     3001 tcccgccgga ggatggcggt ggcatggagt aaacctgata cccgcgataa tcgccgctta
     3061 tcggagtgcg ttcgaccgct ttataggctg ctaaatcttc tttagtgatc aagccaccgt
     3121 ttttctgcat ctcctgggcg atctgttccg caatcgtgcc tttatagaat tcgtccgggc
     3181 cgttttcagc aatcatctcc aagctctttg ccaggttcgc ctgcaccagc gtgtcgccct
     3241 ttttcagcgg ctcgccctct ttccagaaga tagctttact gttttcgtga ttcggcaaca
     3301 cttcgctacc gtaggttttg agatcgtcag ccagcgcgtc gttaacgata aaaccatcgc
     3361 gtgccagttt aaacgcgggc tgcacgactt tgttcagcgg catggtgccg tatttatcca
     3421 gcgccagcga gaaacctgct accgtacccg gtgtgccgga agccagatgc gaagtgagtg
     3481 attttttgct gtccgggttg ccctgatcat cgaggaacat atcgcgggtc gctttggcgg
     3541 gtgccatttc gcggaaatcg atagccgtgg tattgccatt tttcgagcgg attaacataa
     3601 aaccaccacc gcccagattc cctgcctgcg gatgcgttac cgccagcgcg tagcccaccg
     3661 ccacggcggc atcaacggca ttcccgccct ccttgagaat atccaccccc acctgagtgg
     3721 cagtggcgtc cacagacgct accattccct gtttcgcgcg taccgggtgg aagacatctt
     3781 cctccacacc atacgagacg ggcggcgcag gaggcgcggc ggcggcgcta aaacaacttc
     3841 ctgagagcag agcagcaatg gccacccggc gtaaaaacgt cggttttatc atcgttattc
     3901 tccagagatt aaggggcaac cccagctaag cctggtatat aactctgaat taatcatcgt
     3961 tttgtcggga agcgagtaaa cttaaaggat atcttcagag gaggatacgc gatgaaacga
     4021 cttctgattc ttacggcact cctgccgttt gtcggctttg cacagcccat taatactctg
     4081 aacaacccta accagccggg gtatcagata cccagccagc agcggatgca aacctagatg
     4141 cagactcagc aaatccagca aaaagggatg ctgaatcagc aactgaaaac gcaaactcag
     4201 ttgcaacagc agcatttaga aaaccagata aacaataatt ctcagcgggt gttgcagtca
     4261 cagccggggg agcgaaatcc cgcccggcag caaatgctgc ccaacaccaa cggcgggatg
     4321 ttaaacagca accgtaatcc ggatagttcg ttgaatcagc agcatatgct gccggagagg
     4381 agaaacggcg acatgctgaa tcagcccagc acgccgcagc ctgacattcc gttgaaaact
     4441 attgggccgt aaagttcgga ccaatcacgt caatcgcatc ggtacagatg caatccacac
     4501 cccagcgcag caactctgct gcgcgctggg gtttattgac ggtataaacc agaatccgca
     4561 gtccggcgtc tttcaactgc atcactcgcg ctttattgag taacttatga ttgagatgaa
     4621 tagagacgca gcccagccgc gcggtcagtt cgcgccagtc gtcgcgccac tcatccagca
     4681 acaaaccgcg cggcagttcc ggtgccgcct gttgtgcagc ttctaaagca tcaatctcaa
     4741 acgatgacag cagcggcggc gtcataccgg cccacagctc gcgtgccgcc agcgccacca
     4801 ttttgcccgt taatggcccg gtgccggtgg tgggtttgat ttcgatattc gccatcatcc
     4861 cgtgttcgcg gcaacgttcc gccacctgcg aaagcaacgg tagcggctca cctttaaaca
     4921 ttttgctgta ccaactgccc gcatccacgc gcagtaaatc ctgccagttc agttcacccg
     4981 cgacgcccca gccgttgctg gtacgttcga gattgtcgtc atggagcagg aagatctcgc
     5041 catctttcga taacttcgcg tcaaattcga tcatcttatg accgtatttt gccccgacgt
     5101 cgattgccgc cagggtgttt tccggggcca gcttaccgcc gccacgatga gcgacgatgc
     5161 ggggataagg ccagttactc atactcgttg tcctgtttca ccatcaaaaa gatgcagctg
     5221 attttccgcc agatgcagcc acagcgtgct gcctgccgtc gggcgctcct gatgcgccag
     5281 tcgcaccacc agcttctgct cgccccagcg tccgtgcgcc aggttatctg cgccgaggat
     5341 ctccagcgtg tccatcacca tcggtacgcc gccttctgcc tgcgagctta gcgcaatatg
     5401 ttccgggcga atgccgagag tcattttacg cccggcatac tgacggtagc caccgtttag
     5461 cggcagctca ataccgccgt ccagttcgaa atgcgtgcct tcgttattca cgcggcctgt
     5521 cagcaggttc atcgccggac tgccgataaa actcgctaca aacaggctgg cgggcttttc
     5581 gtagacttca actggtgtgc caatctgttc ggcaacaccg ccgttcatca ccattactcg
     5641 ctgggcgagc gtcatcgctt caacctgatc gtgagtaacg tagagtgaag tcgttttcag
     5701 gcgacggtgc aactgttgca gttcaagacg catctgcacg cgcagcttgg catcgaggtt
     5761 agagagcggc tcatcaaaca ggaacaccgc cggatcgcgc acaatcgcgc ggcccatcgc
     5821 cacacgctgg cgctgaccgc cggaaagctc gcgcgggcga cgtttgagca gaccgtccag
     5881 ctccagaatg cgcgccgctt ctttaacgcg ctcggcaatt tgctgcttgc ccatgccgcg
     5941 aattttcagc ccccacgcca tgttttcttc gacactcata tgcggataaa gcgcgtagtt
     6001 ctggaacacc atcgcaatcc cgcgatcttt tggctccatt tcagtcacgc gctggtcgtt
     6061 gatccagata tcgccttctg tcacccgctc cagcccggca accatgcgca gcagcgtcga
     6121 tttcccgcag ccagacggcc cgaccatcac gataaattcg ccatccgcca catcaagggt
     6181 cagcggttta atgacctggg ttttaccatc ccagcttttg gttactgcct gtaatttcag
     6241 tcctgccatc ttatttctca ctatcgacca ggccgcgcac gaaggcacgc tgcatcacta
     6301 aaacaatcac caccggaggg ataagcgtta acaacatcgc cgccatcact gagttccatt
     6361 ccgtggtgcc ttcgcctgta gcgatcatcc ctttgatccc tgccacggtg gtgccgagat
     6421 ccacatcggt aataatcaac aacggccaca aatactgatt ccagccgtag ataaaggtga
     6481 tcacaaacag cgccgccaga ttagttttgg agagcggaaa aacgatgtcg caaaagaagc
     6541 gcattggcga tgcgccgtcg atccgcgcgg cttccaccag ctcatccggc agcgtcataa
     6601 agaactggcg gaataggaaa gtagcggtcg ccgaggccat cagcggcagc gttaaaccgg
     6661 cgtagctgtc gagcatctgc aggttggcga tgacttccac cgtcgggaag atacgtactt
     6721 caaccggcag catcagggtg ataaaaatca tccagaagaa gaggttacgt agcggaaaac
     6781 gaaaccagac aatggcaaat gccgagagca tcgagacggt aattttgccg agcgtaatgc
     6841 tgaacgccat cacaaagctg ttaagcaaca tccgccagaa cggcgcgcta ttcgtgccta
     6901 ccccgttcac ccagatgttg tggatgtttt ccagcagatg tgtgccgggg atgagcgtca
     6961 tcggcgcggc atagacggcc tgtttatcca gcgtcgccgc gacaaacgcc acgtacagcg
     7021 ggaagaggat caccgcgatc ccgaggatca gcatggtatg gctgaatatc gtcagccacg
     7081 gacggttctc aatcattggt aacgcacctt gctttcaaca tagcggaact gcaccaccgt
     7141 cagcacgatg acgaggaaca tcaacaccac cgactgtgcg gcagacgaag ccagatccag
     7201 tccggtaaaa ccttcgcggt agatcttata aatcagcgtc gtggtggcct gaaccggccc
     7261 gccggacgtg gcggcgtcga tcaccgggaa ggtgtcgaag aaggcataca ccaggttcac
     7321 taccagcagg aagaaactca ccggggcgat aagcggcagc gcaatcttaa agaagcggcg
     7381 aatcggccct gcaccgtcga tggctgcggc ttcgatcaac gaacggggaa tggattgcag
     7441 cgcggcatag aagaacagga agttgtagct gatttgcttc catactgagg caaacaccac
     7501 cagaaacatt gcctgaccgc tgttttgcgc gtggttccag tcgtagccga actccgcgag
     7561 aaaatgggtg atcagcccgc gaccggggtt aaacaggaag atccacaata cggcggcaac
     7621 ggcgggagcc acggcgtaag gcagcaacat taaggtttga tagaaacggc tgccgcgcac
     7681 gatgtactcc accagcgccg caaagaacag cgataccagc aaaccgctga cggtgacaaa
     7741 ggtgctgaat tttatcgtcg tccagaagga gtcgagatag tagctgtcat ggaacagcgt
     7801 gacgaagtta tccaggccga caaactggct ggagaaacca aacggatcga cgctttgtag
     7861 cgagtaccac aacgcttcgc ccgcaggcca gataaaaaag ataacggtga tgatgagctg
     7921 cggcgcgacc agcagataag gcagccagcg cgagcggaac accggacggg atgatgacat
     7981 tacggttaat tcctgaactg tgccggatgc gcttcgctta tccggcctac acgcgatgcc
     8041 aggtcagata agcgaaacgc atccgacatt acactgatta agacttcgtc gatttctcaa
     8101 agcggcgcag caactgattt ccacgctcaa cggcggtatc cagtgcctgc tgtggtgtct
     8161 tcttaccggt ccacacgctc tccagctctt catccacaat cacgcggatc tgcggcatgt
     8221 tgcccagacg cagccctttg gtgaacggca acggcggctt attcagcatc tgacgcgtcg
     8281 cggtatccgc ccctgggttt ttctcataaa agccctgctc acgggtcagg tcatacgctg
     8341 ctttggtgat tggcagataa ccggttttct gatgccactc ggcagcgttt tctggcttcg
     8401 cgaggaaatc gaggaacttc gccacaccgg tatacgtttc tttatcttta ccctgcatca
     8461 cccacaggct ggctccgccg ataatggcgt tttgtggcgc atctttcgca tcggcgtcgt
     8521 aaggcatcat gcctacgccg tagttaaatt tggcgtactc gcgaatgttg gcaagagaac
     8581 cggaagaggc ggtggtcatc gcgcaatcac cgttatagaa cttctcggtg gattcatcct
     8641 tacgaccgac gtagctgaag tcgcccttct tgttcatctc ctcgagcatg gcgatgtgtt
     8701 tcacctgctc cggcttgttg aactccagca ccgcgtccgt gccgtcaaag ccgttgtttt
     8761 tgctggcaaa cggcagaccg ttccaggcgc taaagttttc cagttggatc cagccctgcc
     8821 agccgctggc gtagccgcac ttcatgccgg aggctttcag tttcgcggca tagtccgcca
     8881 gatcctgcca ggttttcggc ggctgttccg ggtctaatcc tgctttcttg aaggcgtctt
     8941 tgttgtaata gagaacgggg gtcgagctgt tgaatggctg ggagagtaag tggcccgttt
     9001 tgctgtcgga gtagtaacct gaaaccgtcg gcacaaactg cgactcatcg aactgaatcc
     9061 ctgcctcttt aaacacgtca tacaccggtt taatggcttt cgacgccatc atggtggcgg
     9121 tgccaacttc ataaacctgc aaaatagccg gcgcgttgcc ggtacgaaat gcggcaatcc
     9181 ccgcgcttaa attctgttcg tagttgcctt tataggtcgg tacaattttg taatccgggt
     9241 tttcggcgtt aaaacgttgg gccagagaat ccacctcttt acccagttcc ccttccatag
     9301 aatgccagaa cggaatggtc gtcactgcct gtgcattccc cattaacgcc agtccgagcg
     9361 ccagtgctga agctgtataa tgtaacggtt tcatcgttta tctctcttgt tgtaccgaat
     9421 gcgcgaattc acgcgtttta tgctcgcggg gtaacatgac atgctcgaat tacagaaaaa
     9481 taactttttt gttacatttg taagatagta aggtgtcaga aagatgacaa ggcggtgacg
     9541 gcgtgggtga gggaaaatgg gagatggggc acggataagc gggaaaatat agaaggtctg
     9601 aatcaaactc tacagattgc tcatcgtttc atgccggatg cggcgtaaac gccttatcag
     9661 gcctacaaga tcgtgcaaat tcaacatatt gccactcacc cagtaggcct gataagcgca
     9721 gcgcatcagg caattttaca tttgtcacct gtctcaaagg agtcttttga ctccctatca
     9781 atcaacgtgt tattacccgc ctaaatacgc acttctcacc gcttcattcg ccagcagcgc
     9841 atcaccagta tcggaaagca ctacatggcc gttttccagc acgtagccgc gatccgccag
     9901 ctttagcgcc tggttggcgt tctgctcgac gagaaagata gtcatcccct gctcgcgcag
     9961 ctgctcgatg gtgtcgaaaa tttgctggat gataatcggc gcaagaccga gcgatggctc
    10021 atcaagcagt agcaaacgcg ggttgctcat cagcgcacga ccaatcgcca gcatctgctg
    10081 ttcaccgccg gacatggtgc ccgcccgctg aatacggcgc tcatgcagac gtggaaacag
    10141 ctcatacacc cactttatgc gctcctggaa ctggtcgcgt tcagcaaaaa aaccgcccat
    10201 cgccaggttc tcttccaccg tcatccgcga gaagacgcga cgcccttccg ggacaatcgc
    10261 caccgcttcg cgcatgattt tcgctgtctg ccagtcggta atgtctttat catcaaacac
    10321 aattcgcccg ctggtggcac gcggatcgcc gcataacgtg ccgagcaagg tggttttccc
    10381 cgccccgttc gcgccaatca gcgtgacaat ctcgccctga ttgatatgca ggctcacctc
    10441 atgcagcgcc tggattttgc cgtagtgggc gctgactttg tcaaaggaca acatgacttt
    10501 ttccatctta tgcctcacct aaataggcac ggatcacgtc cgggttatta cggatctgct
    10561 ccggcgtacc gtttgccagc ggcgtcccct gattgaccac gtaaattcgg tccgaaattc
    10621 ccatcaccag cttcatatcg tgttcaatca acaagatagt ggtgttgtga tgattgcgca
    10681 gttcggcaat cagctcatcc agctctttcg tctctttcgg gttaagacct gccgcaggtt
    10741 cgtcgagcat taaaatctcc ggctgcgtca ccatgcagcg ggcaatctca agacggcgct
    10801 ggtcaccata ggccaggtta ctcgcctgac ggttggcgtg ttccagcaaa ccaatgcgct
    10861 caagccaggt cgcggcgcgg tcgagcgctt cgctctgggc gcgacggaag gatggcgttt
    10921 tcaacaggcc agagaacagc ccggttttca gttgctgatg ctgcgccacc agcaggtttt
    10981 caattaccgt catttcacgg aacagacgca catgctggaa ggtgcgcacc acgcccatgc
    11041 gggcaatttg ctgccccggt aaaccttcca ggtgctgatc gcgcagtaaa atggtgccgc
    11101 cggtgggttt gtagaatccg gtcagacagt taaaaaccgt ggtttttccg gcaccgttag
    11161 ggccgattaa cgagacgatc tcctgcgggt acagttcaag attgacgttg ttcaccgcca
    11221 gcaggccgcc gaagcgcatc atcaggccgt taacagataa taatggctga ctcatgcctg
    11281 ctctcctttc gctgcgccgt ttttcagctt cagttgcggg cgcgtcatgg gcagcaagcc
    11341 ctgcggacgc cagatcatca tcagcaccat caaaccaccg agcattaaca tgctgtattc
    11401 gttgaaatca cgcatcaact cgcgcgacac caccagcaaa attgccgcca gaatcaccgc
    11461 aaattgcgag cccataccgc cgagcaccac tatcgccagc acaaacgccg attcggcaaa
    11521 ggtgaaggat tccgggctga caaagccctg acgcgccgca aacagcgttc cggcaaaacc
    11581 ggcaaacgcg gcacttatgg taaaggcagt cagcttgata cgacgcgggc ttaagcccag
    11641 cgaacggcag gcgatttcat cttcacgcaa cgcttcccac gcacgcccca gcggcatccg
    11701 cagcaggcgg ttaatgacaa acaggcttag caccaccagc agcaacgcca ccaggtagag
    11761 gaagatgaca cgatcggagg gatcgtattt caggccaaag aaattactga acgtgtccca
    11821 gccgccttca cgagcggtac ggctgaactc gagtccgaag agtgtcggtt tcgggatctg
    11881 actgattccg ttcgggccgc cggtaatttc ggtgttattg agcagcaata tgcgcacaat
    11941 ttcgccgaaa ccgagggtaa cgatcgccag atagtcaccg cgcaaacgca gcaccggaaa
    12001 accgagcagg aagcccgccg ccgctgccat taatccagca atcggcaggc aggtccagaa
    12061 gcccaagccg taatagtgat tgagcagcgc aaaagtgtaa gcgccgatgg cgtaaaaacc
    12121 gccgtacccc agcaccagca gaccagaaag accaacaacc acgttcagcc cgagaccgag
    12181 gataatgtag atcatggtca gggtggcaat atccaccgtc ccgcgtgaaa ccataaacgg
    12241 ccacgccacc gcaagcacca acagcgccac gaggaacagt ttctgcttca ccgtggagcc
    12301 atcaatggcg ggcagaataa acttcggtcc ggaaacgctt ttcaaccctt tatggaaagc
    12361 cggtcgcaaa agctggaaga aaaagaccac cgccgtgccg ataaacaccc actgccaacg
    12421 gacatccgaa gccgtgtcga ccaccagttt ggtgccatcc agctccagtt gcacgcccat
    12481 aaagacgccc gccagcacaa agaacatcgc ggcagagagc agcgccattg caatatgcat
    12541 cggtttcata ctttctctac ctccgggcga cccagaatac cggtcggcat caccagcagc
    12601 accagaatca gcagggcgaa tgagaccaca tctttatatt ccgtactcag ataggcagaa
    12661 gagagcgcct ccgcaatccc cagaatcagg ccgccaatca tcgctcccgg aatgctgcca
    12721 atcccaccga gcaccgccgc ggtaaaggct ttcatcccgg ccataaagcc gatgtagggg
    12781 ttaatgacgc cgtagaactg accgagcagc acacccgcca ccgccgccat cgccgcgcca
    12841 atcacaaagg tcagcgcaat cacccggtcg gtgttaatgc caagcagact cgccattttc
    12901 agatcttccg cgcaggcacg acacgcgcga cccatgcggg aatagcgaat gaaaatcgtc
    12961 agcgccagca tggcgaggaa ggtaacaatc cagatcaccg cctgcatggt ggtaatagag
    13021 gcagagaagt tttcgctatg ccccaccacc cactgaccgt taaacaggct cggcagcgcc
    13081 acgtcgcgcg aaccttcggt caggctgacg tagttttgca ggaagatgga cataccgatt
    13141 gcagagatga gtgcaatcag gcgcttagag ttacgcaccg ggcggtaagc cacccgttcg
    13201 atactccagc cgtaggcgct ggcaatgacg attgcgccga cgaatcccgc agctaccagc
    13261 agccagccgg tatcaatgcc catcatcatc agcgcggcga tgatcataaa tgagacgtag
    13321 ctgccaatca tataaacctc gccgtgggcg aagttgatca tgccgataat gccgtaaacc
    13381 atggtgtagc cgatggctat cagcgcgtag gtactgccca gcgtgacgcc gttaaacatc
    13441 tgctgcaaga aatacaaaaa ctgctcagac ataaggtaac ctttctaaac ccgcccgcat
    13501 tttacgggcg gtgggatgat cacttggctg ccgtggatga accgtcggcg tgccactgga
    13561 agacaccaaa atcaaatccc ttaagatcgc ctttttcatc ccagttcagc ggcccaatca
    13621 cggtgtttgc accgttagct tttaaatctt tcaccagcgc cagcggctca tcgctgccgg
    13681 tacgctcaag ggcagtcgcc agagattgca ccgccgcgta ggtgatccag acataaggcc
    13741 cggacggatc tttcttgtct gctttcagcg catcaacgat gccctggttt gccggatcct
    13801 ggtcatagcg ttttggcata gtgaccaaca tgccttcggc ggcatcaccg gcaatgttcg
    13861 acaacgacgc attacccaca ccttccggcc ccataaactg ggttttcagg ccaacggaac
    13921 gggcctggcg cagcatctgc cccatttccg ggtagtaacc gccgtagtaa acgaagtcga
    13981 tgttttcttt tttcaggcgg gcgatcagcg cggagaaatc tttctccccg gcggtaatac
    14041 cgtcgaagaa gacgacgttg gcgttagccg ctttcagccc gtcctgcacc gaacgcgcca
    14101 gcccttcgcc atactgttgt ttgtcgtgaa tgatggcgat gcgctggggc ttcaccgtct
    14161 caagaatgta ttttgccgcc gttggcccct gggaagagtc cagcccggca gtacgcataa
    14221 tgtgttgata accgcgttgg gtcagctccg ggttggtcgc tcccggcgag atcatcagaa
    14281 taccttcgtc ttcatagata tctgacgcag gctgggtaga agaagaacac agatgaccaa
    14341 taacgtattt aatgccgtca ttaacgattt tgttggcgac cgcaacggct tgtttcgggt
    14401 cgcatgcgtc gtcatattcc acgccaacca gtttatcgcc cttaattccc cctttggcat
    14461 taatgtcttt aatt
//
LOCUS       DACAOP010000105        14456 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.105, whole genome shotgun sequence.
ACCESSION   DACAOP010000105 DACAOP010000000
VERSION     DACAOP010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14456
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.105"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..617)
                     /locus_tag="IT892_003679"
     CDS             complement(<1..617)
                     /locus_tag="IT892_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416276.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HAP3136841.1"
                     /translation="MKKVLLQNHPGSEKYSFNGWEIFNSNFERMIKENKAMLLCKWGF
                     YLTCVVAVMFVFAAITSNGLNERGLITAGCSFLYLLIMMGLIVRAGFKAKKEQLHYYQ
                     AKGIEPLSIEKLQALQLIAPYRFYHKQWSETLEFWPRKPEPGKDTFQYHVLPFDSIDI
                     ISKRRESLEDQWGIEDSESYCALMEHFLSGDHGANTFKANMEEAP"
     gene            complement(745..2706)
                     /locus_tag="IT892_003680"
     CDS             complement(745..2706)
                     /locus_tag="IT892_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP3136842.1"
                     /translation="MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGH
                     LLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAG
                     DPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
                     SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVA
                     KDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIV
                     TSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCR
                     YLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSA
                     INLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLL
                     GSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ
                     DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMAT
                     RPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGG
                     SADKKKAAPRKRSAKKSPPADEVGSGAIA"
     gene            complement(2711..3754)
                     /gene="selD"
                     /locus_tag="IT892_003681"
     CDS             complement(2711..3754)
                     /gene="selD"
                     /locus_tag="IT892_003681"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HAP3136843.1"
                     /translation="MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLV
                     GNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMA
                     IAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
                     RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFAN
                     IEGVKAMTDVTGFGLLGHLSEMCQGAGVQARVDYEAIPKLPGVEEYIKLGAVPGGTER
                     NFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKATAAEFGIELTAIGEL
                     VPARGGRAMVEIR"
     gene            complement(3871..4422)
                     /locus_tag="IT892_003682"
     CDS             complement(3871..4422)
                     /locus_tag="IT892_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HAP3136844.1"
                     /translation="MDALELLINRRSASRLAEPAPTGEQLQNILRAGMRAPDHKSMQP
                     WHFFVIEGEGRERFSAVLEQGAIAAGSDDKAIDKARNAPFRAPLIITVVAKCEENHKV
                     PRWEQEMSAGCAVMAMQMAAVAQGFGGIWRSGALTESPVVREAFGCREQDKIVGFLYL
                     GTPQLKASTSINVPDPTPFVTYF"
     gene            4583..6439
                     /gene="sppA"
                     /locus_tag="IT892_003683"
     CDS             4583..6439
                     /gene="sppA"
                     /locus_tag="IT892_003683"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAP3136845.1"
                     /translation="MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQ
                     VSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVN
                     TIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQY
                     YLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRD
                     DMSPAAREADSRWIGELWQNYLNTVAANRQIPAEQVFPGAQGLLEGLTKTGGDTAKYA
                     LENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYDYALKTPADTGDSIGVVFAN
                     GAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAA
                     RAAGKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGV
                     HTDGVSTSPLADVSITRALPPEAQLMMQLSIENGYKRFITLVADARHSTPEQIDKIAQ
                     GHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYVDEPTFFDKVMDNMSG
                     SVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANMR"
     gene            6606..7622
                     /gene="ansA"
                     /locus_tag="IT892_003684"
     CDS             6606..7622
                     /gene="ansA"
                     /locus_tag="IT892_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAP3136846.1"
                     /translation="MQKKSIYVAYTGGTIGMQRSEQGYIPVSGHLQRQLALMPEFHRP
                     EMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYDDYDGFVILHGTDTMAYTASALS
                     FMLENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNR
                     TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIY
                     PGISADVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELQEASDRGIVVVNLTQCMSG
                     KVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQELDTETIRKAMSQNLRGEL
                     TPDD"
     gene            7633..8274
                     /locus_tag="IT892_003685"
     CDS             7633..8274
                     /locus_tag="IT892_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416282.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyrazinamidase/nicotinamidase"
                     /protein_id="HAP3136847.1"
                     /translation="MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRG
                     EAVIASQDWHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQ
                     KAIAAVFHKGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFT
                     VLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQG"
     gene            complement(8367..9725)
                     /locus_tag="IT892_003686"
     CDS             complement(8367..9725)
                     /locus_tag="IT892_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136848.1"
                     /translation="MEQYDQIGARLDRLPLARFHYRIFGIISFSLLLTGFLSYSGNVV
                     LAKLVSNGWSNNFLNAAFTSALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAAT
                     GAAFVPDMYWLIFFRFLMGTGMGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPM
                     LSAAIGVVVIAFFSWRIMFLLGGIGILLAWFLSGKYFIESPRWLAGKGQIAGAECQLR
                     EVEQQIEREKSIRLPPLTSYQSNSKVKVIKGTFWLLFKGEMLRRTLVAITVLIAMNIS
                     LYTITVWIPTIFVNSGIDVDKSILMTAVIMIGAPVGIFIAALIIDHFPRRLFGSTLLI
                     IIAVLGYIYSIQTTEWAILIYGLVMIFFLYMYVCFASAVYIPELWPTHLRLRGSGFVN
                     AVGRIVAVFTPYGVAALLTHYGSITVFMVLGVMLLLCALVLSIFGIETRKVSLEEISE
                     VN"
     gene            complement(9842..10600)
                     /locus_tag="IT892_003687"
     CDS             complement(9842..10600)
                     /locus_tag="IT892_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP3136849.1"
                     /translation="MAAKDRIQAIKQMVANDKKVTVSNLSGIFQVTEETIRRDLEKLE
                     DEGFLTRTYGGAVLNTAMLTENIHFYKRASSFYEEKQLIARKALPFIDNKTTMAADSS
                     STVMELLKLLQDRSGLTLLTNSAEAIHVLAQSEIKVVSTGGELNKNTLSLQGRITKEI
                     IRRYHVDIMVMSCKGLDINSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFV
                     QLADFSHINYIITDKSPGAEWIAFCKDNNIQLVW"
     gene            complement(10737..11717)
                     /gene="ydjG"
                     /locus_tag="IT892_003688"
     CDS             complement(10737..11717)
                     /gene="ydjG"
                     /locus_tag="IT892_003688"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent methylglyoxal reductase"
                     /protein_id="HAP3136850.1"
                     /translation="MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILE
                     AHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGD
                     RQLYKNLSPESIREEVAASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKSE
                     GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYS
                     PLEQGLLTGTITRDYVPGGARANKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLAL
                     AWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREMAEALER"
     gene            complement(11727..12674)
                     /locus_tag="IT892_003689"
     CDS             complement(11727..12674)
                     /locus_tag="IT892_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HAP3136851.1"
                     /translation="MDNLDVICIGAAIVDIPLQPVSKNIFDVDSYPLERIAMTTGGDA
                     INEATIISRLGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLV
                     TEDGERTFVTNRNGSLWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGKALTEIFTQA
                     KARQMIICADMIKPRLNETLDDICEALSYVDYLFPNFAEAKLLTGKETLDEIADCFLA
                     CGVKTVVIKTGKDGCFIKRGDMTMKVPAVAGITAIDTIGAGDNFASGFIAALLEGKNL
                     RECARFANATAAISVLSVGATTGVKNRKLVEQLLEEYEG"
     gene            complement(12679..13515)
                     /locus_tag="IT892_003690"
     CDS             complement(12679..13515)
                     /locus_tag="IT892_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAP3136852.1"
                     /translation="MLADIRYWENDATNKHYAIAHFNVWNAEMLMGVIDAAEEAKSPV
                     IISFGTGFVGNTSFEDFSHMMVSMAQKATVPVITHWDHGRSMEIIHNAWTHGMNSLMR
                     DASAFDFEENIRLTKEAVDFFHPLGIPVEAELGHVGNETVYEEALAGYHYTDPDQAAE
                     FVERTGCDSLAVAIGNQHGVYTSEPQLNFEVVKRVRDAVSVPLVLHGASGISDADIKT
                     AISLGIAKINIHTELCQAAMVAVKENQDQPFLHLEREVRKAVKERALEKIKLFGSDGK
                     AE"
     gene            complement(13536..>14456)
                     /locus_tag="IT892_003691"
     CDS             complement(13536..>14456)
                     /locus_tag="IT892_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="HAP3136853.1"
                     /translation="DVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFKPGD
                     RVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNM
                     DTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDV
                     LEKRLAMAEQLGATVVINGAKEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVM
                     RGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTH
                     IYDYRDVQQAFEESVNNKRDIIKGVIKISD"
BASE COUNT         3664 a         3792 c         3303 g         3697 t
ORIGIN      
        1 tctggggctt cctccatgtt tgctttaaag gtattggctc catggtcgcc agaaagaaaa
       61 tgctccatta aggcacaata actttcgcta tcttcgatac cccattgatc ctctaaagac
      121 tcgcgtcttt tacttatgat atcgatcgag tcaaaaggaa gcacatgata ttggaaggta
      181 tctttgccag gttcaggctt tcgcggccag aactccagcg tttcagacca ttgcttatga
      241 tagaatcgat aaggtgcgat caattgtagc gcctgtaact tctcgatact gagcggctca
      301 atacctttag cctgataata atgcagttgt tctttttttg ctttaaaacc ggcccgaaca
      361 ataagcccca tcataattaa tagataaaga aaagagcatc ccgcggtaat caggcctctt
      421 tcattcaaac cgttggatgt tatcgctgcg aacacaaaca ttacagcgac aacacatgtt
      481 aaataaaacc cccacttaca aagcagcatg gccttatttt ctttaatcat ccgttcaaaa
      541 ttactattaa atatttccca gccattaaaa gaatacttct cgctcccagg atggttttgt
      601 aataaaactt ttttcatcac attccctgtt attacatact ttagaggcga taattttatc
      661 catgcaaaaa aaatatccaa cgaattttct tgatccgctg gatatttcag aatatgactc
      721 gaatagcacg aaagattcac tcgcttacgc tatcgccccg cttccgactt catctgctgg
      781 cggacttttt ttcgcactac gtttacgcgg tgcagccttt ttcttatcag cactgccacc
      841 actgcccgga gccacaatgc cgcgaaactg ccgcaccggc gtacgtttgg cttgatcaat
      901 aagctgatat agcgtcccca ccagcggctg cataaagtcc tgatagcgac actgcttttc
      961 gctgatttgc gtcagcaccg attcccagtg cgcggtcatg tccggtcgcg tcgccatctc
     1021 cggcagcgaa tggaatagcg cttttccggc gtcggtggag tggatatagc gccctttttt
     1081 ggtcaggaaa ccacgcttga acaacagttc aataatcccg gcacgcgttg cctctgtccc
     1141 cagaccatcg gtcgcacgga ggatcttttt cagatcttta tcctgcacaa agcgcgcgat
     1201 cccggtcatc gccgaaagca gtgttgcatc ggtaaaatgg cgcggcggct gggtttgccg
     1261 ctctaccact tcaccttttt cacacagcaa ctcatcgcct ttcgccacca caggcagtgg
     1321 cgtgccgtcg ttttcttcat cgcgctcttt gctgcctaac agcgtgcgcc agcctgcttc
     1381 agcaagaaaa cgcgctttag cgacaaattt gcctttggca atgtccagtt cgataacaca
     1441 cttgcggaac accgcatccg ggcagaattg catcagatac tgacgggcaa tcaggttata
     1501 gaccttcgct tcgttctccg tcaggttgat cgcagaactc cgtgcggtcg gaatgatggc
     1561 gtggtgcgca tcgacctttt tgtcatccca acagcggttg cgtatatctg gatctaccac
     1621 tggctgcggc aacagatccg gtgcatgaac actgatggca ttcatcaccg cgtggcgtcc
     1681 ggcaaaatgt tcttctggca aatagcgaca atcagaacgc ggataagtga ttagcttgtg
     1741 cgtttcgtac agtttctggc agatatcaag cacgttctgc gcactcagac caaaacgttt
     1801 tgccgcttca atctgcaacg ctgaaagcga aaaaggcagc ggcgcggatt ctgattcccg
     1861 tttatcgtta tagctggtga caatagccgg ttgaccacta atgcggttaa ccacatgctc
     1921 cgccagtgga cgatgtaaca agcgcccttc ttcatcctgg tacggttcac acgcttcgct
     1981 cggttgccag atagcggtaa accgctcatc ggcaggtgtc acgatatgtg ctttgacttc
     2041 aaagaagtct ttcgccacga agttttcaat ctcttcatcg cggcgcacca ccagcccaag
     2101 cacgggcgtc tgcacgcgtc ccacggaaag tacgccctga taaccggcat tgcgaccgag
     2161 aatggtatac gcacgggtca tattgatgcc gtacagccag tcggcacgcg ctcgcgccag
     2221 cgcagaaacg cacagcggta caaactcact gttggaacga agacggtcga tcgcccgctc
     2281 aaccgcctgc gggttcaggt cgtttatcaa gcaacgctgt acctgctggc gcttttccgg
     2341 tgccagttgc agatagtcca gcacttcatc caccagcaat tgcccttcac gatccgggtc
     2401 cccggcgtga acgatttcgc tggcttcatg caggaaccgt ttgatgacgt taagttgttt
     2461 ggtcacggag ggtcggggct gtaattgcca cttttccggg acaatcggca aatccgcaag
     2521 attccagcgc gcatagcggc tgtcgtaggc gtctggctgc gcctgctcaa gcaggtgacc
     2581 gatacaccag gtcaccacct gaccattacc gcactcgata aagccatcgc ctttccggtg
     2641 cggtttgggc aggacatcag caatggcgcg cgccagactc ggtttttcgg caataaacaa
     2701 ccgcattgaa ttaacgaatc tcaaccatgg cacgaccgcc gcgcgctggc accagttcgc
     2761 caattgccgt cagttcaatg ccaaactcgg cggctgtagc tttgacctca ttttctgctt
     2821 ccggcatgac cgccagcagc aaaccgccag aagtttgcgg atcacacagc agatcgcgca
     2881 cttcacgcgg catttcaccc atcagatgac cgtagctggc aaagttacgt tcagtgccgc
     2941 caggtactgc gcccaactta atgtactctt caacaccggg gagtttcggg atcgcttcat
     3001 agtcgacgcg tgcctgcaca ccagccccct gacacatttc gctcaagtgg cccagcagac
     3061 caaagcccgt aacgtcggtc atcgctttta cgccttcgat gttggcaaag gacgcgcctg
     3121 cgatgttcat ccggcacatc acttccgtcg ccagtccctg atgttctggt ttcaacagtg
     3181 attttttctc agccgtggta agaacgccga tccccagcgg tttcgtcagg aacagtttgc
     3241 atccggcttg tgcggtactg tttttcttca cccgctcggt cggtacgatc cccgttaccg
     3301 ccagaccaaa aatcggctcc ggcgcatcga tggagtgacc gccagccagc gcaatacccg
     3361 cctgacgaca tgcatagcgt ccaccttcgg tcacttcgcg ggcaatttct ggggaaagtt
     3421 tgttaatcgg ccagccgagg atcgcaatcg ccataatcgg tttgcccccc atcgcgaaga
     3481 tatcgctgat ggcgttagtc gccgcaatgc ggccaaaatc gaaaggatta tcaacgatcg
     3541 gcataaagaa gtcggtggta ctgataacgc tggtgccatt gcccagatcg tacaccgccg
     3601 catcgtcgcg ggtttcatta cccacaagca aattcggatc aacaaacttc gcctgctcac
     3661 tatgcaggat ggtttccaac acttttgggg aaattttaca gccgcaacca gctccgtggc
     3721 tgtattgggt caaacgaatc gagttctcgc tcatggacat ctcctgtcaa tgcaatccgg
     3781 gtatggtaac cctcattccg tgaagtgata agtgagagtg tctgaattcc tgcgcctttg
     3841 ctcacaatcc agacagtttc gcgacaatta tcagaaataa gttacaaacg gcgtcgggtc
     3901 cgggacgtta atcgacgtag atgctttcag ctgcggcgta ccgaggtaga gaaaaccgac
     3961 aattttatcc tgctcacggc aaccgaatgc ttcacgcact accggacttt cagttaatgc
     4021 gccactgcgc cagatgccgc caaacccctg ggcaactgct gccatttgca tcgccatgac
     4081 cgcgcatccg gcagacattt cctgttccca gcgcgggact ttatgattct cttcgcattt
     4141 cgccaccacc gtgatgatga gcggtgcgcg gaacggcgca ttacgggctt tgtcgatagc
     4201 tttgtcatca ctaccggcag caatcgcccc ctgttccagt acggcgctga aacgctcgcg
     4261 cccttcccct tcaatcacaa aaaaatgcca cggttgcatg gacttatggt ccggcgcacg
     4321 catacccgca cgcaggatgt tttgcagttg ttcacccgtt ggcgcgggtt cagccaagcg
     4381 ggaggcgcta cggcgattga tcaatagttc gagtgcatcc atttgattaa ctcctgtcgt
     4441 gatatttatt cacaaaatta acacgagagt ggattttgtt acagcacagt ccgcaattcc
     4501 tgctgacaag taccggttgg gtcattacga taaccacatc tattgcgcct gtgacaggtg
     4561 tgaccttaag ttgggagaat acatgcgaac cctttggcga tttattgccg gattttttaa
     4621 atggacgtgg cgtctgctga atttcgtccg tgaaatggta cttaacctgt tctttatttt
     4681 cctcgtactg gttggtgtgg ggatttggat gcaggtcagt ggtggtgatt cgaaagaaac
     4741 ggccagtcgt ggcgcactgc tgctggacat ttctggtgtg atcgtcgata aacccgacag
     4801 ttctcagcgg tttagtaaat taagccgcca gctgcttggt gccagttccg atcgtctgca
     4861 ggaaaactca ctgtttgata tcgtcaacac tattcgccag gcgaaggacg accgcaatat
     4921 caccggtatt gtgatggatc tgaaaaactt cgcaggcggc gaccaaccgt ctatgcagta
     4981 catcggcaaa gctctgaaag agtttcgtga cagcgggaaa ccggtttatg ccgttggcga
     5041 gaactacagc caggggcaat attatctcgc cagtttcgcc aataaaattt ggctgtctcc
     5101 gcaaggcgtg gttgatctgc acggctttgc caccaacggt ctgtactaca aatcgttgct
     5161 ggataagctg aaagtttcca cccatgtgtt ccgcgtgggt acgtataaat ctgccgttga
     5221 accgtttatt cgtgatgata tgtcaccggc agcccgcgaa gctgacagcc gctggattgg
     5281 tgagctgtgg caaaactatc tgaatactgt tgccgctaac cggcagatcc ctgctgagca
     5341 ggtattccct ggcgcgcaag ggttgcttga gggtttaacc aaaaccggtg gcgataccgc
     5401 gaaatatgca ctggaaaaca agctggtcga tgcactggca tcgagtgcgg aaatcgaaaa
     5461 agcactgacc aaagaattcg gctggagtaa gactgataaa aattatcgcg ccatcagtta
     5521 ttacgattac gcattgaaaa cgccggcaga taccggtgac agcatcggtg tcgtctttgc
     5581 taatggcgca attatggatg gcgaggaaac tcaggggaat gttggcggtg ataccactgc
     5641 ggcacaaatc cgcgacgctc gccttgaccc gaaagtgaaa gcgattgtcc tgcgtgttaa
     5701 tagcccaggc ggcagcgtta ccgcgtctga agtgattcgc gctgaactgg cagcagcccg
     5761 ggcagcgggt aagcctgtgg ttgtatcgat gggcggcatg gcggcatctg gtggttactg
     5821 gatttccacg ccagctaatt acattgtggc taaccccagc accctgaccg gttctatcgg
     5881 tatcttcggc gtgatcacca ccgtagaaaa tagtctggat tcgattggtg ttcatactga
     5941 tggtgtctca acttcaccgc tggcggatgt ttctatcacc agggcactgc cgccggaagc
     6001 gcagctgatg atgcagttaa gcattgagaa tggctataaa cgctttatca cgctggttgc
     6061 tgatgcgcgt cattcgacgc cggagcagat tgataaaatt gcccagggcc acgtctggac
     6121 cggtcaggat gcaaaagcta acgggctggt cgatagtctc ggggatttcg atgatgcggt
     6181 cgccaaagca gcagagctgg caaaagtgaa acagtggcat ctggaatatt acgttgatga
     6241 accgaccttc ttcgacaaag tgatggacaa catgtctggt tctgtccggg caatgttgcc
     6301 agatgcgttc caggccatgt tacctgcacc gctggcctcg gtagcctcta ccgttaaaag
     6361 tgaaagtgac aagctggccg cgtttaatga cccacaaaac cgttatgcgt tttgcctgac
     6421 ctgcgccaac atgcgttaag tcttgtactg agtggccgac agatcgtcgg ccacattatt
     6481 ttttacgtcg acgaatcctc ttcccgctgt ttcgccccat atttccttat ccgcatagta
     6541 tcaggtgcgc tccccctgcc tcacgtatat acttttgctc tttcgatatc attcatatca
     6601 atatcatgca aaagaaatca atttacgttg cctacacggg cgggaccatc gggatgcagc
     6661 gttccgagca gggttatata ccggtgtcag gtcatctaca acgccaactg gcgctgatgc
     6721 cggaattcca tcgcccggag atgccagatt tcaccattca tgaatatacg ccgctgatgg
     6781 attcttcaga tatgacgccg gaagactggc agcatattgc tgaagatatt aaagcgcact
     6841 atgacgacta tgatggtttt gtcattctgc acggcaccga cacgatggcg tataccgcct
     6901 ctgcgctgtc gttcatgctc gagaatctcg gtaaaccggt cattgtgaca gggtcacaaa
     6961 tcccgctggc tgagttacgc tctgacggac aaattaatct gctgaatgcg ttgtacgttg
     7021 cggcgaatta tccgatcaac gaagtaacgc tctttttcaa taaccgattg tatcgcggca
     7081 accgcactac caaagcccat gccgatggtt ttgatgcgtt tgcctctcca aaccttcctc
     7141 cgttactgga agcaggtatc catattcgtc gtttgaatac gccacccgcc ccgcacggtg
     7201 aaggggaatt aatcgttcat ccaatcaccc cacaaccaat tggcgtagtg acgatttatc
     7261 cagggatttc tgctgacgtc gtgcgcaatt ttctgcgcca accggtgaaa gcattgattc
     7321 tgcgctccta tggcgtgggt aatgcgccac aaaacaaagc cttcctgcag gaattacaag
     7381 aagccagcga tcgcggtatt gtggtggtca acctgacaca atgtatgtcc ggtaaagtga
     7441 acatgggtgg ttatgccacc ggtaacgccc tcgcccatgc cggcgtaatt ggcggtgcag
     7501 atatgactgt agaagccacg ctaaccaaac tgcattacct gcttagccag gaactggata
     7561 ctgaaaccat tcgcaaggcc atgagccaaa acctgcgcgg cgaactgacg ccggatgatt
     7621 aaggagactg taatgccccc tcgcgccctg ttactggtcg atttacaaaa tgatttctgt
     7681 gctggtggcg cgctcgccgt gccggaaggt gacagtacgg tggatgtcgc taaccgcctg
     7741 attgactggt gccagtcgcg cggtgaagcg gttatcgcca gtcaggactg gcacccggcg
     7801 aatcacggca gttttgccag tcagcacggt gtagagcctt atacgccagg ccaactcgac
     7861 ggtttgccac aaaccttctg gccagatcac tgtgtgcaga acagtgaagg cgcacaatta
     7921 catccgttac tgcaccaaaa agcgatcgca gcggtgttcc ataaaggcga aaatccttta
     7981 gttgacagtt acagtgcctt ttttgataac ggccgtcggc agaaaacctc tctcgatgac
     8041 tggttacgcg atcatgaaat cgatgaattg atcgttatgg gcctggctac tgactattgc
     8101 gtgaagttta ccgtgctgga cgcgttacag ttaggttata aggtaaacgt gattaccgat
     8161 ggttgtcgtg gcgtgaatat ccagccccag gacagtgcgc acgcgtttat ggagatgtca
     8221 gcagctgggg caacgctata tacgctggca gactgggaag agacacaggg gtaattttac
     8281 gctggcctac aattctgtac tggcattgta ggccaaataa aacacgtcag tggcacatct
     8341 ggcaattgat gccatcaacg aaagatttaa ttcacctcag aaatctcttc caacgacacc
     8401 ttccgcgttt cgatgccaaa aatggagaga accagcgcac agagcaataa catgacacca
     8461 agtaccataa acaccgtgat cgacccataa tgtgttaata atgccgcaac gccatagggc
     8521 gtgaagactg cgacgatccg tccgacggca ttaacgaaac ccgaaccgcg caggcgtaaa
     8581 tgcgttggcc aaagctccgg gatataaacc gccgacgcga agcaaacata catgtataaa
     8641 aagaagatca tcaccagtcc atagattaaa atcgcccact ctgtagtctg aattgaatag
     8701 atatagccta acacggcaat aataataagt aaggtggagc caaataaccg acgaggaaaa
     8761 tgatcaataa ttaatgccgc aataaatatt cctaccggag cgccaatcat aataacagcg
     8821 gtcattaata ttgatttatc gacatcaatg ccggagttaa caaatatggt cggtatccat
     8881 acggtgatgg tataaagcga aatgttcatt gcaattaaaa cagtaatcgc gactaatgta
     8941 cgtcgtaaca tttcaccttt aaacaggagc cagaaagtac ccttgattac tttaaccttg
     9001 ctgttgctct gatacgaagt aagcgggggt aaacgaatac tcttctctct ttcaatttgc
     9061 tgctctactt cacgaagttg gcattctgca cctgcgattt gccctttccc tgccagccat
     9121 cgtggcgact cgataaagta tttacctgag agaaaccagg ctaacagtat gccaatacca
     9181 cccagcagaa acattattcg ccaactaaaa aaagcgataa ccaccacgcc tatcgccgca
     9241 gacagcatgg gcgaccagtt accaacaaat gagagccgcg cggaccattt tccacgcacc
     9301 gtcgcgggga taaactccgt aaatgaggca tagccaacca taatcagcgc ccccattcct
     9361 gttcccatca ggaagcgaaa gaagatgagc cagtacatat cagggacaaa agcggcccct
     9421 gttgcagcaa taccgacgat gagaagattt atgcgaaacg ccctgcgccg cccaaagtag
     9481 tcaccaataa acccaccagt aagtgagccg atgaaataac caaacattaa tgccgaggta
     9541 aaggcggcat tgaggaaatt atttgaccat ccattgctta ccagctttgc taagacgaca
     9601 ttaccggagt aactcaaaaa ccctgttaat aacagactaa agcttataat accaaatata
     9661 cgataatgaa accgggccaa aggcaagcgg tccagtcttg cgccaatttg atcatattgt
     9721 tccattaggt gcctcggatt tgctaaaaag gtagcaattg cggcaaattc acttgccgca
     9781 tctttatcat cattttattt caaggcgcag gaacaaataa tattgacaac gtgtgcttaa
     9841 attaccacac cagctggata ttattgtctt tgcaaaatgc tatccactct gcacccggtg
     9901 atttatcagt tattatgtaa ttaatatgac taaaatcagc taactggaca aaagctttgc
     9961 gatcaaactt agagtgatca accaataacg caacttctgt cgcctgacgg atcattgtct
    10021 ttttgatttc agcttccgct tcattagagt ccagcgcgcc gctgttaata tcaagacctt
    10081 tacaactcat taccatgata tcgacatgat agcgcctgat gatctcttta gtaattcttc
    10141 cttgcagtga aagtgtattt ttgtttagtt ccccacccgt tgaaacgact ttaatttctg
    10201 actgagccag aacatgaatc gcttccgccg agttggttag caacgtcagg ccactacggt
    10261 cctgtaacaa tttgagcaat tccattacgg tactactgga atcggctgcc atggtggttt
    10321 tattgtcgat aaagggtagt gccttgcgtg caataagctg cttctcttca taaaacgatg
    10381 aagcgcgctt ataaaaatgg atattctccg tcaacatcgc tgtatttaaa acagcaccac
    10441 cataggttct ggtcaaaaag ccttcatctt ccagcttctc aagatcgcgg cgaatggttt
    10501 cttcggttac ctgaaaaatc ccactcaaat ttgagactgt caccttttta tcgttggcaa
    10561 ccatttgctt aattgcctga atcctgtctt ttgccgccac gattacaccc ctgtatcttt
    10621 ttacatcaca ttagcgcgat tatcgcataa ccgatgttta ctttcaaaat aacctgtttg
    10681 aatcacagat tttcatcaca gttttcacag aaacagaggt gaatcgtgtt gagtatttaa
    10741 cgctccaggg cctctgccat ttccctcatc aatgttgcgt ctgcatccga taagttgata
    10801 ttcagtgccg cgacattttc gcgtacctgt tccggtgcag tagccccact aagaatggag
    10861 attaaatcac tctgttttaa tatccacgcc agtgccagag tgggaattgt gcactgataa
    10921 cgagcacaaa gtggctgcca ctgttcaagc atatcaatca ctttcagcat gttttcacgc
    10981 tggaaccaga ctttatttgc ccgagcgccg cccggaacgt aatcacgagt gatggtgccg
    11041 gtcaacaatc cctgctctag cggggaataa acctgaacca caatgccatt atcacgacat
    11101 agtggcagca gttcgttttc cattgcccgg tcgaggatac tgtatttcgc ctgaataata
    11161 tccagttcac catattgcag atactcgcgg atatggtcag catcgacgtt agcagcgcct
    11221 atagcgcgaa ttttcccttc agactttaac tcattaagca ctgcgacagt ttcagcgatc
    11281 ggcgtaaaaa atggcggcac cgactgccag tgcgtcatgt agatatcgat gtaatcaata
    11341 cccagacgtt gcaagctcgc tgctacctct tcgcggatag attccgggga aaggttttta
    11401 tacaactgcc gatcgccaac tttgttgaat aaacttcctt ttcgttccca gacaatgccg
    11461 catttggttt ctactacaac ctgttcacgg ggcagttttt ttaacgcctg accgacgata
    11521 acttcactat tgccaaagtt atatcctggc gcagtatcaa tcagattaat gccacaacga
    11581 tgggcttcaa gaatcgtatc aatacatatt tgccgatcga gatcgccatt ccatgcagga
    11641 ccgccgccaa tggcccatgt ccccaacccc attcgcgaaa gcgtaatatc cgttgtgcct
    11701 aaaggtatct ttttcatttg ccttcattat ccttcgtatt cttccagcaa ttgttcgacc
    11761 agctttctgt tttttacgcc ggtggtggca ccgacgctta gaaccgagat agccgccgtt
    11821 gcattggcaa agcgtgcgca ttcacgcaga tttttgcctt ctaacagtgc cgcaataaaa
    11881 cctgaagcaa agttatcgcc cgcgccaatg gtgtcgatgg cggttattcc tgcgaccgcc
    11941 ggcaccttca tcgtcatgtc accacgcttg ataaagcagc cgtctttacc cgttttaatc
    12001 accaccgttt ttacgccgca cgcaagaaag cagtcagcaa tttcatccag tgtctctttc
    12061 ccggtgagta attttgcctc ggcaaaatta ggaaacagat aatcgacata actcaatgct
    12121 tcgcaaatat catccagcgt ttcattcaac cgcggtttga tcatatcggc acagataatc
    12181 atctgccggg ctttagcttg cgtaaaaatt tctgttagcg ctttaccatc caatagtgga
    12241 ctgttgaaaa tactggccag tgataataat ttcgcctgag aaaaccgcgc aaaatcaaca
    12301 tcgtcaatat tcaatttcca cagactgcca ttacggtttg tgacaaacgt ccgctcgcca
    12361 tcctccgtca ccagtccaac gttaatagag gtatctatgc tgacgtcctg cttcaggctt
    12421 tgaatatcaa tattctcttt gcggcaatgg tcgagaataa attgccctgc ggcatcttta
    12481 ccaatacgac tcattaatgc tgtgcgatgg cccagacgag aaataattgt tgcttcattt
    12541 attgcatcac ccccggtggt cattgcgatt ctttcaagag gataagaatc cacatcaaag
    12601 atatttttac tgaccggttg caatggaata tcaacaatag cggcacctat acaaataacg
    12661 tcgagattat ccatatcatt attccgcttt gccatcagaa ccgaacagtt taattttttc
    12721 caatgcccgt tcttttacag ctttacgtac ttcacgttct aaatgcagga aaggctgatc
    12781 ctggttttct ttcactgcaa ccattgcggc ctgacagagc tccgtatgaa tgttgatttt
    12841 cgcgataccc aacgaaattg cagttttaat gtcggcatca ctgatccccg atgcaccgtg
    12901 caaaaccagc ggaacagaaa cggcatcgcg tacgcgtttg acgacctcaa agttcaattg
    12961 tggctctgac gtataaaccc catgctggtt gccgatggcg acagccaatg aatcacagcc
    13021 cgtacgttca acaaattcag ccgcctggtc aggatcggta tagtgatagc ccgccagcgc
    13081 ttcctcataa acggtttcat taccgacatg ccctaattcc gcctctaccg gaatacccag
    13141 cggatggaag aaatcgacag cctctttggt taaacgaata ttttcttcga aatcaaacgc
    13201 ggaagcatca cgcattaatg aattcatacc atgagtccag gcgttatgaa taatctccat
    13261 actccgacca tgatcccaat gagttattac cggcaccgtt gctttttgtg ccattgatac
    13321 catcatgtga gagaaatctt caaatgaggt gttaccgaca aaacctgtac caaaagaaat
    13381 aataaccggg gatttcgctt cttcggctgc gtcgataacg cccatcaaca tttctgcatt
    13441 ccatacgtta aaatgggcaa ttgcataatg tttatttgtg gcatcgtttt cccaatatct
    13501 gatatctgcg agcatgttct gttctcccgt attaattaat cgctaatttt aataacgcct
    13561 ttaataatgt cgcgtttgtt gttaactgac tcttcaaatg cctgttgtac atcccgataa
    13621 tcgtaaatat gcgtcaccat cgatttcaca tcgaatcgcc ctgaagaaat agcttcaatc
    13681 gtgaccggat aacgattggc atagcggaat accgtctgga tagtgacttc gcgattgatt
    13741 ttgaggaaat tgattgccga atcgccgggt acagtaccaa caatcataat tttaccgccg
    13801 cgcattacca gataaggtgc ctgtttaacg gtgaccgcag aacccgctgt ttcgaaaaca
    13861 atatctgcgc ccatgtcttc ggtaaattgc tgacagcgtg caatagtgtc ttcttttgcg
    13921 ccgttaataa ccactgtcgc accaagctgt tccgccattg ccagacgttt ttccagcaca
    13981 tcaacgacgg caatttccgt tgctcccagg catttgcacg cttgcaacgt catcaaacca
    14041 atacaacctg ctcccagaat aattatcttc ttacccggtt taacatctgc cagcatcgcg
    14101 gcatgcatcc cgactgcggc aggctccacc agcgcccctt ccatcgtgtc catattgtcg
    14161 ggcagtttgt aagtaaagct ctccggatga cacagatagt gcgttaatgc gccgcggtag
    14221 ttgggttgtg tcgccataaa atcaacgtcc gggcagatgt tatatttgcc ttccagacag
    14281 taacgacagt gaccgcaagg aacgccaggt tcgatattta cccgatcccc cggtttaaat
    14341 ttgcgcacgc ggcttcccac agccacaacc gtcccggcgc attcatgacc caggccaatt
    14401 tcttgatttg ggtctttagg cggaataaac gggcctgatt caaaaccatg tacatc
//
LOCUS       DACAOP010000106        14404 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.106, whole genome shotgun sequence.
ACCESSION   DACAOP010000106 DACAOP010000000
VERSION     DACAOP010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14404
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.106"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            14..1339
                     /locus_tag="IT892_003692"
     CDS             14..1339
                     /locus_tag="IT892_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HAP3136854.1"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFI
                     NNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
                     NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKRLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRMLGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
     gene            1448..1684
                     /locus_tag="IT892_003693"
     CDS             1448..1684
                     /locus_tag="IT892_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HAP3136855.1"
                     /translation="MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
                     DTIADIARKYNASSWKVTSMRIDNNSTATAVLYK"
     gene            1696..2289
                     /gene="rclC"
                     /locus_tag="IT892_003694"
     CDS             1696..2289
                     /gene="rclC"
                     /locus_tag="IT892_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species resistance protein
                     RclC"
                     /protein_id="HAP3136856.1"
                     /translation="MEKYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSAREILKQRSNESSSTLKTEY"
     gene            complement(2448..2576)
                     /locus_tag="IT892_003695"
                     /pseudo
     CDS             complement(2448..2576)
                     /locus_tag="IT892_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308365.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            2879..3730
                     /locus_tag="IT892_003696"
     CDS             2879..3730
                     /locus_tag="IT892_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP3136857.1"
                     /translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
                     FMHVPLGEYIRKRRLCRAAILVRLTAKSMLDIALSLHFDSQQSFSREFKKLFGCSPRE
                     YRHRDYWDLANIFPSFLIRQQQKTECRLINFPETPIFGNSFKYDIEVSNKSPDEEVKL
                     RRHHLARCMKNFKTDIYFVSTFEPSTKSVDLLTVETFAGTVCEYADMPKEWTTTRGLY
                     ASFRYEGNWENYPDWVRNIYLIELPARGLARVNGSDIERFYYNEDFVEKDGNDVVCEI
                     FIPVRPV"
     gene            complement(3870..8126)
                     /gene="fdeC"
                     /locus_tag="IT892_003697"
     CDS             complement(3870..8126)
                     /gene="fdeC"
                     /locus_tag="IT892_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001635811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like adhesin FdeC"
                     /protein_id="HAP3136858.1"
                     /translation="MSHYKTGHKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
                     ARAQHAVQPRLSMGNTTVTADNNVEKNVASFAANAGTFLSSQPDSDATRNFITGMATA
                     KANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
                     RTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
                     SGWKKSPDIEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
                     DPHAISAEVTYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLAKQLDTDSIRE
                     RRVLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTLSLGLVVSKATHGLK
                     NVQWEAPSLLAEGGKITGQGSQWQVTLPAYRPGKDNYYAISAVAYDNKGNASKRVQTE
                     VVITGAGMSADRTALTLDGQSRIQMLANGNEQRPLVLSLRDAEGQPVTGTKDQIKTEL
                     AFKPAGNIVTRSLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDGMS
                     KTVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLR
                     FVPQDTNGVTVGAISEIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
                     LDAAHSSITLNPDKPVVGGTVTAIWTAKDAYDNPVTSLTPEAPSLAGAAAVGSTASGW
                     TNNGDGTWTAQITLGSTAGELEVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAED
                     HVKAGESTTVTLIAKDAHGNTISGLSLSASLTGTASEGATVSSWTEKGDCSYVATLTT
                     GGKTGELRVMPLFNGQPAATEAAQLTVIAGEMSSANSTLVADNKAPTVKMTTELTFTV
                     KDAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVATLTLGSAAGQLSVM
                     PRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITLTVVDSYGNPL
                     QGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIELMSTVAGEHSITASVNNAQKTVTVKF
                     KADFSTGQATLEVDGSTPKVANDNDAFTLTATVKDQYGNLLPGAVVVFNLPRGVKPLA
                     DGNIMVNADKEGKAELKVVSVTAGTYEITASAGNDQPSNAQSVTFVADKTTATISSIE
                     VIGNRAVADGKTKQTYKVTVTDANNNLLKDSDVTLTASSENLVLDPKGTAKTNEQGQA
                     VFTGSTTIAATYTLTAKVEQANGQVSTKTAESKFVADDKNAVLAASPERVDSLVADGK
                     TTATMTVTLMAGVNPVGGSMWVDIEAPEGVTEKDYQFLPSKADHFSGGKITRTFSTSK
                     PGVYTFTFNALTYGGYEMTPVKVTINAVAAETENGEEEMP"
     gene            8679..8768
                     /locus_tag="IT892_003698"
                     /pseudo
     CDS             8679..8768
                     /locus_tag="IT892_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308358.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
     gene            9242..9343
                     /locus_tag="IT892_003699"
     CDS             9242..9343
                     /locus_tag="IT892_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136859.1"
                     /translation="MKENKVQQISHKLINIVVFVAIVEYAYLFLHFY"
     gene            9707..9970
                     /locus_tag="IT892_003700"
     CDS             9707..9970
                     /locus_tag="IT892_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAP3136860.1"
                     /translation="MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPY
                     VTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
     gene            9970..10110
                     /gene="rpmJ"
                     /locus_tag="IT892_003701"
     CDS             9970..10110
                     /gene="rpmJ"
                     /locus_tag="IT892_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAP3136861.1"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     gene            complement(10145..10372)
                     /locus_tag="IT892_003702"
     CDS             complement(10145..10372)
                     /locus_tag="IT892_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136862.1"
                     /translation="MQAAPQREETEWRVQSKRGLMPAYRGEAGQQVNIKIMEYSERNV
                     RQLASNEQEEYIPRKINVGVINTPTLIRSDY"
     gene            11195..11737
                     /gene="ecpR"
                     /locus_tag="IT892_003703"
                     /gene_synonym="matA"
     CDS             11195..11737
                     /gene="ecpR"
                     /locus_tag="IT892_003703"
                     /gene_synonym="matA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECP biosynthesis operon DNA-binding
                     transcriptional regulator EcpR"
                     /protein_id="HAP3136863.1"
                     /translation="MECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKD
                     FVFINLSTDSLSEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAG
                     LSRDIRKELVYVINGRFLRKDIKKDKITDREMEIIRMTAQGMQPKSIARIENCSVKTV
                     YTHRRNAEAKLYSKIYKLVQ"
     gene            11812..12399
                     /gene="ecpA"
                     /locus_tag="IT892_003704"
                     /gene_synonym="matB"
     CDS             11812..12399
                     /gene="ecpA"
                     /locus_tag="IT892_003704"
                     /gene_synonym="matB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="common pilus major fimbrillin subunit EcpA"
                     /protein_id="HAP3136864.1"
                     /translation="MKKKVLAIALVTVFTGMGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     gene            12457..13125
                     /locus_tag="IT892_003705"
     CDS             12457..13125
                     /locus_tag="IT892_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpB"
                     /protein_id="HAP3136865.1"
                     /translation="MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIKNS
                     TDSGRLINIRLERLSSPLDDGQVISMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKF
                     IPVK"
     gene            13151..>14404
                     /locus_tag="IT892_003706"
     CDS             13151..>14404
                     /locus_tag="IT892_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136866.1"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
                     SEQTRQQLMALANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
                     IGQSSVNTLSSNLSYNLGVYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRTQRVNKLFSRGRGVGAPLAWQVWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTLSWAATGYGYDNQAVG"
BASE COUNT         3821 a         3475 c         3256 g         3852 t
ORIGIN      
        1 acaggaaatc atcatgaata aatatcaggc agtgattatt ggttttggca aggctggaaa
       61 aacattagcc gtcacgctgg caaaagcagg ttggcgagtg gctctcatcg aacaatcaaa
      121 tgcaatgtat ggcgggacct gtattaatat cggctgcatc ccaaccaaaa cattggttca
      181 tgacgcacag cagcacacag attttgtccg tgccatacag cgtaaaaatg aagtggttaa
      241 ttttttacgt aataagaatt ttcataatct tgcggatatg cccaatatcg acgtgatcga
      301 cggccaggcg gagtttatca ataatcatag cctgcgtgtt catcggcctg agggaaatct
      361 ggaaattcat ggcgagaaaa tttttattaa taccggtgca caaaccgtgg ttccgccaat
      421 tcctggaatt accaccacgc caggagtata tgacagcacc ggattactta atctaaaaga
      481 attgcctggg catttaggta ttttgggcgg cggatatatt ggcgttgagt tcgcctctat
      541 gttcgctaat tttggcagca aggtaaccat tttagaagca gcttcgctgt ttttgcctcg
      601 ggaagatcgg gatattgctg ataatatcgc gacgatttta cgcgatcagg gcgtcgatat
      661 tatcctcaat gcccatgtgg agcgaatcag tcaccatgaa aatcaagtgc aagtgcatag
      721 cgagcacgcc caactggcgg tggatgcact gttaatagct tccggtcgtc aaccggctac
      781 cgcttcgtta catccagaaa atgccggtat cgcagtaaac gagcgcgggg caattgtcgt
      841 tgacaagcga ttacatacca ccgcagacaa tatttgggcg atgggagatg ttaccggcgg
      901 gctgcaattt acttacatat cactggatga ttaccgcatt gtacgtgatg agttactggg
      961 tgaaggcaaa cgtagtactg atgatcggaa aaatgtgcct tattccgtat ttatgacacc
     1021 gcccctgtcc agggttggta tgacagaaga acaagccaga gagagtggtg ctgatattca
     1081 ggtggtgaca ttgcctgtag ctgcaattcc gcgtgccaga gtgatgaatg atactcgtgg
     1141 ggtattaaaa gcgattgttg ataataaaac ccaacgtatg ttaggggcat cactgctgtg
     1201 tgttgactcc cacgagatga tcaatatagt gaaaatggtg atggatgccg ggctgcctta
     1261 tagcatatta cgcgatcaga tatttactca tccgtcgatg agcgaatcac tcaatgatct
     1321 attttcatta gtcaaataaa ctcaaaatca gacgccagaa caaatattct ggcgtctcag
     1381 agaaaagaat cttattaatt ctctgttact ctataacttc ttaatcactt cattgatggt
     1441 attttatatg tttaaaaaat ctgttttatt tgcaacacta ttatctggcg ttatggcatt
     1501 ttccaccaat gcagatgata aaataattct gaaacatatc agcgtctcgt cagtatcagc
     1561 atcaccgaca gttctggagg ataccattgc tgatatagcc agaaaatata atgcttcatc
     1621 ctggaaagtc acatcgatgc gaattgataa taattcaacc gcaacagcag tattgtataa
     1681 ataaggatgt tcacaatgga aaaatacctg cacctgttaa gtcggggaga taaaattggc
     1741 ctgacattga ttcgtctgag tattgcaatt gtttttatgt ggattgggtt attaaagttt
     1801 gtcccttacg aggcagacag cattacacca ttcgtcgcaa acagtccact aatgtcgttc
     1861 ttttatgaac acccggaaga ctataaacag tatctgactc acgaaggcga atacaaacca
     1921 gaagcaaggg catggcaaac ggccaataat acctatggtt tttccaacgg tcttggcgtc
     1981 gtggaggtga ttattgctct gctggttttg gctaatcctg tcaatcgctg gttaggttta
     2041 ttgggaggac tgatggcatt taccacgccg ctggtaacac tctcattttt aatcaccacc
     2101 ccggaggcat gggtacccgc attgggtgac gctcatcatg gtttccctta tttatccggt
     2161 gctggtcgcc tggtattgaa agatactctg atgctggcag gtgcagtcat gataatggca
     2221 gattcggcgc gggaaattct taaacaacgc agtaatgaat ccagttcaac gttaaaaact
     2281 gaatattgat aatccgaaca ctgtctgttg ttcacttttt caggcgtcag gccccctttc
     2341 tgatgatgaa gcctgacgcc atattaccgg agatatgaca gagtgaagat caatatcact
     2401 ccctgttaaa aggtttttgt cgtcttaggt aaaatacatg attaatatca atcatgtatt
     2461 tttacagcaa gacaaccacg aacaaattca ggattaaaat gttttaccga ctccccaaca
     2521 taacccaaat caagcgaact aatttgtgcc atttctttat ctgtcagtga gaaatcgatt
     2581 tttgatgggc atctgcaata ctctgaagca gactatacgg aaaattccac tgtcagtccc
     2641 tccattaggc atgaacaatg agtctacgtt aaaacgtaac ctcaaagtag tatgtggatt
     2701 ttgatatcac ttatgcaaaa aattcattaa taatgtagga ctgaaacctc tctattttcg
     2761 gggacaacga agcagacgct atcagtgctt ttgccttcgc ccttgctatt tttgatacac
     2821 ttagggccca gggtataacg aaaatgtgcg atatgacaaa gaattaacgg agaatgagat
     2881 gatcaggcag aagattctac agcagctcct ggagtggatt gagtgcaatc ttgagcaccc
     2941 tatttcaatc gaagatatcg cacagaaatc tggctacagc agacgcaaca tccagcttct
     3001 gttccgaaat ttcatgcatg tgcctttggg agaatacatt cgcaaacgaa ggctttgtcg
     3061 tgccgccatt cttgtccggc tcaccgcgaa atctatgctt gatattgcac tctctttgca
     3121 ttttgattca cagcagtcat tcagccgcga atttaaaaag ttattcggct gctctccccg
     3181 tgaataccgc caccgtgatt attgggatct cgcaaatatc ttcccttctt ttttaatacg
     3241 tcaacagcaa aagacggagt gtagattaat caactttcct gagacaccta tttttggcaa
     3301 ctcatttaaa tatgacattg aagtgtcgaa taaatcaccg gatgaagaag tcaaactacg
     3361 acgtcatcat ttagccagat gtatgaagaa ttttaagacg gatatctatt tcgtttccac
     3421 gtttgaaccg tcaacaaaat cggtcgattt gctcacggtt gaaacttttg ctggtacggt
     3481 atgtgaatat gctgacatgc caaaagagtg gacaacgacc cgaggacttt atgcctcttt
     3541 ccgttatgaa ggaaactggg aaaattatcc tgactgggtg cgtaacatct atctgataga
     3601 gttacctgcc agggggttag ccagagtgaa cggcagcgat attgagcgct tttattacaa
     3661 tgaagatttc gtagaaaagg atggcaatga tgttgtttgc gaaattttta ttcccgttcg
     3721 tccggtttag ttggtcacta tctcttattg agttttatcc ttgcctgata ctatttaatc
     3781 agtatcaggc aaggtattca gtgaataatg gcgttgaata tttcaacacc attattcttt
     3841 attagatcgt aactttcata ctattcaaat tatggcatct cctcctcgcc attttcagtc
     3901 tctgcagcaa cggcgttaat tgtcaccttc acaggcgtca tttcgtaccc gccatacgtc
     3961 agtgcgttga atgtgaacgt atagacacct ggcttgctgg tactaaatgt acgcgtgatt
     4021 ttcccacctg agaaatggtc agccttcgac ggcaggaatt gataatcctt ctccgtcact
     4081 ccttccggag cctcaatgtc gacccacata cttcctccta cgggattgac tcccgccatc
     4141 agggtaaccg tcattgttgc agtagtcttc ccgtccgcca ccagagaatc tacacgttct
     4201 ggagatgcgg cgagcaccgc gtttttatca tccgcgacga atttagattc agcagttttc
     4261 gtcgatacct gaccgttggc ctgttccact ttcgccgtga gtgtatatgt cgctgcgata
     4321 gtggtagagc cggtgaaaac agcctgtcct tgctcattag ttttcgccgt ccctttagga
     4381 tccagaacta aattttccga gctggcagtc agcgtcacgt cgctatcctt caacaggttg
     4441 ttattggcat cagtcaccgt aactttatac gtctgtttgg ttttgccatc cgccactgca
     4501 cggttgccaa tcacctcaat actggagatg gtcgccgtag tcttatcggc cacaaacgtt
     4561 acagactgcg cattcgaagg ctggtcattt cctgccgacg ccgtgatctc atacgttccg
     4621 gcagtcacgg agaccacttt cagttccgct ttaccctcct tgtcggcgtt caccatgata
     4681 ttaccgtctg caagcggttt gacgccccga ggcagattaa agacgaccac agcgccaggc
     4741 agaaggttgc cgtattgatc cttaaccgtt gccgtcagcg taaaggcatc attgtcgttt
     4801 gccacttttg gcgtgctgcc atcaacctcc agggtcgcct gaccggtact gaaatccgcc
     4861 ttgaatttca ccgtaaccgt cttctgagca ttattcactg aggccgtgat gctgtgttcc
     4921 cccgcaaccg ttgacataag ctcaatgtcc actttccctg ccgcattggt tgttactgta
     4981 ttccccgtct tgctggtcac accctgcggt aaagtcagcg taacttcttg cccctgcaac
     5041 gggttaccat agctgtccac gacggtcagg gttatctggt tagcagactg tccattagcc
     5101 agttggttat taaccttcac tgtcatatca cgaatctcag ccttagatgc gtcacctgca
     5161 acgttcagca ccagtggctg agcaacggca ttttggccgt tcactcgcgg catcacagac
     5221 aactgacccg cggcagatcc cagcgttaag gtcgccacgt agaccccatt acctttctct
     5281 gtccagtttc ctgctgaagg acgctcactc cccgtgctgg cggcaccgct aaacactggt
     5341 gcatctggct tcagcccggt gaccgggttc ccgtacgcat ccttcacggt gaaggtgagt
     5401 tccgtcgtca ttttgacggt cggagcctta ttgtccgcaa caagcgtaga gttcgctgat
     5461 gacatctctc cggcgatgac cgtcaactgc gcggcttcgg tggctgctgg ctggccgttg
     5521 aagagcggca tgacacgaag ctcgcccgtc tttccgcctg tagttaacgt agcaacatag
     5581 gaacagtcac ctttttcggt ccaactggaa acggtcgccc cttcagaggc ggtccccgtc
     5641 aaacttgccg acaacgaaag accactgata gtgttgccat gtgcatcttt tgcaataagc
     5701 gtcacggttg tgctttcgcc ggcttttacg tgatcttctg cgacagagac tttcgactgg
     5761 tttgaagata acgcatcagc caccacggtt acttttgccg catttgctgc cgcatcctgt
     5821 ccatttagct tcggcataac ttctaattca cccgccgtag agccgagagt aatctgcgca
     5881 gtccacgtcc catcaccatt atttgtccag ccagatgccg tagaacctac agcagcggca
     5941 cccgctaatg acggcgcttc cggcgtgagg ctggtcacag ggttgtcata ggcatctttt
     6001 gccgtccaga ttgccgtaac tgtaccgcca accaccggtt tatcaggatt cagggtgatg
     6061 gacgaatgtg ctgcatcaag cggaccggca acaaacttca gcgtttgttg taatgtgccc
     6121 agctgatact gctcgctgaa agcacgcaca acaacgtttc cggcacgggt cgaagaaacc
     6181 gtggcgctgt aaacgcctgg ttttatttcc gaaatggcac caacggttac accattagtg
     6241 tcttgcggaa caaatcgcaa gcggctggct tctcccgtca ccggattacc ctcggagtcc
     6301 accgcagtca acgtcaacgt ataggcttgc tgaccatcag caaccacatc acctgacggc
     6361 tcgttagcgc tcagggtgga gtttgccaca tccatcatcg tggcccgcag ttctgcagtg
     6421 acggttttgc tcatgccatc aacgctaaca gtaatcgttg cctcacctga ctgcgttccg
     6481 gtagtaaaga cagactgata cacccctgct tcagtttcgg tgaactcacc cagtgttggc
     6541 tttgcctgtg atttagtggc cttcagggaa cgagtcacaa tatttccagc cggtttgaag
     6601 gctagttcag tcttgatctg atctttcgtg cccgtgactg gctgcccctc ggcgtcgcgc
     6661 agagacagca ccagcggtct ttgctcatta ccgttagcaa gcatttgaat acggctctga
     6721 ccgtcaagcg ttaacgccgt gcgatcggcg ctcatacctg ctccggtaat gaccacctct
     6781 gtctgcacgc gttttgaggc attgcctttg ttatcgtagg caaccgcaga aatcgcataa
     6841 taattgtctt tgcctggacg ataagccggg agcgttactt gccactgact accctgaccg
     6901 gtaattttgc caccctcagc cagtaatgac ggcgcttccc actgcacatt tttcagtccg
     6961 tgagttgctt tgctgaccac aagccccagg gaaagtgtct gaccaccctt accttcaata
     7021 cgttcaggca gagcaatacg gatcacttca gatttgcggt actcaagaac gatgttgtta
     7081 ttacgctcaa ccaggtcata gcggctgcct gccagtaccc gacgctcgcg aatgctgtct
     7141 gtatcgagtt gtttcgccag aggttcgcca atccgataat taacttccag gccaaagcga
     7201 gtgtcattct caccactctt gccctgctta tgcccggcgc tcagtgtcag aagaggcact
     7261 ggcgtatagg tcacctcggc agaaatagca tgcgggtctt tctggcgctt atctttacca
     7321 aacagcccga cttcatcgcc ataatactgt tcatacatca ggcttgcgcc aagctgcggc
     7381 caggcgggta aatagccctc agcacgaata tcccagccat tcgccgggcg ttcctgataa
     7441 tcctcaatat ccggcgattt tttccagcca gaagcccgaa tataaccatt ggcgctcagt
     7501 ttcagataat cgcgccagta ttccgcacca acaccaatgc gggtatgact acgggataaa
     7561 tcatgatcga taaaagtatt cacccccgcc atccagtcat ttcctgaaaa atgacgccag
     7621 ccaaaaccaa tatttgactg agtacgatcg tctgtacgat gtattgcccc ctgagtgaac
     7681 aacatatttg tcggcgtatc ataaatcgga taaagcattt ccagcgaaga atccttcagc
     7741 gagaaatctt tatcgacatt cagtttgacg cgcgcagtac catatttccc gagccactcc
     7801 tgtatttcct ggttagcttt agctgtggcc attccggtaa taaagttacg tgtcgcatcg
     7861 ctatctggct gactgcttaa aaatgtcccg gcatttgcgg caaacgacgc gacatttttc
     7921 tccacgttat tatcagcagt taccgtagta tttcccatgc tcaaccgtgg ctgaaccgca
     7981 tgctgcgcac gtgccgccat tactggggta aaggtgacag cgagtggaaa aagaacctga
     8041 acagagatat ttgcccacgc cacgcagcgg gccagaactg aataacgaaa tcgtggttgt
     8101 ttatgacctg ttttataatg tgacattgag ataatttcct gatgaacgaa ttaacgaaca
     8161 taggcagaca caaataatgg cgtctgcttg tcagaaaaac cggggatttc ccgatttcct
     8221 tttccgcaga aaaggaaata cctttatgta agaaagtgca ccgccaccta atatatccag
     8281 tgcctatagc cactcatcag gtggttgggc gcgggattat atttttattt atggggggga
     8341 aatttagctt tttgtgcaag tcattaaata gatacctaag ttatatttct tactctgcgg
     8401 acagtgaata attcactatt cagagtgaat aacaatgacc tgcctttaat taaaactatt
     8461 ggaaatacgt cgaaataggt atatatgcca ggataaacca atatattttt tatggatatt
     8521 cattttcctt catcggactg taaattgcgg agatatcgaa cttgcactac ccatcgcaac
     8581 actcaaacag atttatgaat ttcgttcata acccctgaca aattctgccg tctaatcgag
     8641 cttttccctt tacgttatgc ttctcatgaa cgataacaca acttgttcat gaattaacca
     8701 ttccggataa actatgggat caaattcagg catcgaaagg aactggctgg tttccgttaa
     8761 tggattaaat atctattatg ctcccgagag taaaactatc aaatcaatga gtaaccgata
     8821 cagcctcaca aattctttca gataattaac ccgtcactgc ggcacgttct ctcataaggc
     8881 gtgcctgcag tgtaatccag tatgtatccg gcatagttga cggtttaata gaactcaatt
     8941 cctctcccaa gtcaccaaca acgatatctt gtataacacc ccaggagata cgacattatg
     9001 atgagatgcg atatgctcct cagcaccaat caacgcccgg actgggccag tcttgagatc
     9061 agactcattc ccggaactga cttcaggcga catatatcaa tgacgttggt gcaataaaag
     9121 atagttgatg taatacatct attcaaattt gtgatacatg tcaaaaaact ggttgaccaa
     9181 actcgttatt tatataaggg cacttacgaa gtgcactctt ttttaaagcg aggaagtacc
     9241 aatgaaagag aataaagtac agcaaatcag tcataaactg attaatatcg ttgtttttgt
     9301 cgcaattgta gaatacgcct atttatttct ccatttctat taataacgga aataaactgt
     9361 tcacttcagt gatatttaaa atatgcatcc tctccctttt ttgtaagtaa ttattatatc
     9421 cgtgggagag gaatacacgc tgtcaggtaa tcaatcatac tgcgataaat tatcggccag
     9481 taaagtggag ataacctcca ttctcgaaaa atccatactc tcagcaaaac catcatcaat
     9541 cactcatcca ggcgtttatg ggagcgtcac caatggctgc taacaatgcc agagttcccc
     9601 gttgcgaaaa ttccacatcc acaaagagtc acagggattg agtgttgaaa tgatccggat
     9661 gagcatgtat ctttatggtt atgttataac ataacaggta aaaatgatga agcccaatat
     9721 ccatcctgag tatcgtactg tggtgttcca cgacaccagt gttgatgagt actttaaaat
     9781 cggctcgact atcaaaacag accgtgagat tgagctggat ggcgtaacgt atccatacgt
     9841 gacaattgat gtctcttcta aatcgcaccc gttctataca gggaagctga gaacagtggc
     9901 atcagaagga aatgttgcac gattcaccca acgttttggt cgttttgtta gcacgaaaaa
     9961 gggggcgtga tgaaagttct taactctctg cgtaccgcaa aagaacgcca tccagactgt
    10021 cagattgtga agcgaaaagg acggctatat gtgatttgta aatctaatcc acgttttaag
    10081 gccgttcagg gtcgtaagaa aaaacgttga ttcaaaattc gacggattaa cgatatttgt
    10141 ctgattaata atcagatcgg attaatgttg gtgtgtttat aacaccaaca ttaattttcc
    10201 tggggatata ttcttcctgt tcatttgagg ccaactgcct gacgtttctc tccgaatatt
    10261 ccattatctt aatgttgact tgttgaccag cttcgcccct gtatgctggc atcaaccctc
    10321 ttttagactg aacacgccac tcagtctcct ccctttgcgg cgcagcctgc attttcactc
    10381 aaactgttaa gatgataaat gtggtaaatc tgttggtact aacataaaaa cgtttacgcc
    10441 acaggaacag tctgatccac cggtaacccc gtcgccgacg ttcgagtgcc agttagagta
    10501 acgcgcacag ataactgaat gcagtgccct gacaaaaagg ccatcgttcc tgtgacagct
    10561 ggcagccttc gtttaacttc acttaatctg gctcttgggg gcttaccgaa cagatgacgt
    10621 acatacgccc gttcaatttt ccattactta ttggaatgaa cacctgtaac cattttgtgc
    10681 ggcatgttaa tccattaaaa tatcttactg attggcaaat catcttcaat gacagctcat
    10741 catagtttta tattctatcc cttaccctta aaacttgttt ttttactagt ccatcacaca
    10801 gcgcattaag actattccta acacttcagg gcaaagttcc tgaccaatat aaaatgcaag
    10861 taagaattga acgttatatt gccaataacc ttatgaaacc aaatgtcttt ttcttcttat
    10921 caaaaaagca atattttcag tttttctaaa tattgactta accattgaat tccttttccg
    10981 ttcacatatt gacactcatc gggaaaaaaa cataaattta agcccaatcg aaaataatta
    11041 aacttaatct cgtttaacct ttattgatat gtactacgta tcttatttac ttccggttta
    11101 ctaaggaaac tgaatgcacc tgtaaaaatt acaggtttgg aaagtagtga catggcaaag
    11161 tgattacagt agggactatg aggttaaaaa ccatatggaa tgtcaaaacc gttctgataa
    11221 atacatctgg tctccccatg acgcctactt ctataaagga ctatctgaac tgattgtgga
    11281 tatcgacaga ttaatttatc tatcgttgga gaaaattaga aaagatttcg tgtttatcaa
    11341 tctcagtacg gattctttat ctgaatttat aaaccgtgat aatgaatggt tatccgcggt
    11401 aaaggggaaa caggtcgtat tgattgcggc cagaaagtca gaggccttag caaattattg
    11461 gtattacaat agcaatatta ggggcgtggt atacgctgga ctgagtcgtg atattagaaa
    11521 agaactggtc tatgtgatta atggcaggtt cctgagaaaa gatattaaga aagataaaat
    11581 cacggaccgg gaaatggaaa ttatccgcat gacggcccag ggaatgcaac ctaaatcgat
    11641 tgccagaatt gaaaattgta gtgtgaagac agtgtatacc catcggcgta atgctgaggc
    11701 caagctgtac tcaaaaatat ataagttggt tcagtaaact ccaggcaagt tagttttaaa
    11761 aaatgactca ctgggacatc acgtcctcaa ttcaactcgg gaagaaatgc aatgaaaaaa
    11821 aaggttctgg caatagctct ggtaacggtg tttaccggca tgggtgtggc gcaggctgct
    11881 gacgtaacag ctcaggctgt agcgacctgg tcggcaacag ccaaaaaaga caccaccagt
    11941 aagctggttg tgacgccact cggtagcctg gcgttccagt atgccgaagg cattaaaggt
    12001 tttaactcac agaaaggtct atttgacgtg gctatcgagg gtgactcaac ggctaccgcc
    12061 tttaaactga cctcacgtct tatcaccaac acattaaccc agttggatac ctcaggttcc
    12121 acactgaatg tgggcgtgga ttataacggc gcggcagtcg aaaaaactgg cgataccgtg
    12181 atgatcgata ccgccaacgg cgtactgggc ggcaacctta gcccgctggc taacggttac
    12241 aatgccagca atcgtaccac cgcacaggat ggtttcacct tctccatcat cagcggtacc
    12301 accaatggta ccaccgcagt aacagattac agcactctac cggaaggcat ctggagcggc
    12361 gacgttagcg tacagttcga cgcgacctgg accagttaat ctctctgatg taccagcagg
    12421 ggtagccccc ctgctttatt cctggacgga attgttatga aaaagcacct tctgcctctc
    12481 gctctgctgt tttccggaat atctccggcc caggcgctgg atgtcggcga tatatcatcg
    12541 tttatgaaca gtgacagcag cacgctgagc aaaacgatca aaaacagtac cgacagtggt
    12601 cgccttatca atatccgtct cgaacggctc tcttcaccgc ttgacgacgg gcaggttatc
    12661 tcaatggaca agccggatga gttgctactc actcccgcca gcttgctgct acccgcccaa
    12721 gccagcgaag tgatccgctt cttctataag ggacccgcag atgaaaaaga gcgctactac
    12781 cgcattgtct ggtttgatca ggccctcagt gatgcgcagc gcgataatgc caaccgcagc
    12841 gctgtggcca ctgcttccgc ccgcatcggc accattctgg tcgtcgcccc tcgtcaggcg
    12901 aactaccact ttcagtacgc caacggctcc ctgacaaata caggaaatgc gacgctgcgg
    12961 atcctcgcct acggaccttg cctgaaagcc gccaacggta aggagtgtaa agagaattac
    13021 tacctgatgc cgggcaagtc gcgtcgtttt acccgcgtgg acactgcgga taacaaagga
    13081 cgggttgcac tttggcaggg tgataagttc attcccgtga aatagatagc tgtgcagatg
    13141 gataacgaca atgcctttac gacggttctc cccaggactg aaagcccagt ttgccttcgg
    13201 catggtcttt ttgttcgttc agcccgatgc cagcgctgct gacataagtg cgcagcaaat
    13261 aggtggggtg attattccgc aggccttcag tcaggcgctt caggacggca tgagcgtccc
    13321 gctctatatt catctcgccg gtagccaggg tcgccaggac gatcagcgaa tcggcagcgc
    13381 ttttatctgg ctggacgatg gacagctacg catccggaaa atacagctgg aagagagtga
    13441 agataacgcc agtgtcagcg aacaaactcg acagcagctg atggctctgg ccaacgcccc
    13501 gttcaatgag gcccttacca tccccctgac tgacaacgcg cagctggatc tcagcttgcg
    13561 ccaactgctg ctgcagctag tggtcaagcg cgaagcgctg ggcaccgtac tacgctcacg
    13621 tagcgaagac atcgggcagt ccagtgttaa caccctcagc agtaatctga gctataactt
    13681 gggcgtctat aacaaccagt tgcgtaacgg cgggagcaac acatccagct atctgtcgct
    13741 gaataacgtt actgcactgc gcgaacatca tgtggtgctc gacggctcgc tgtacgggat
    13801 cggtagcggt caacaggaca gtgaattata taaagcgatg tatgaacgcg attttgccgg
    13861 tcaccgattt gccggtggaa tgctcgacac ctggaacttg cagtccttag ggccgatgac
    13921 cgccatttca gcagggaaga tttacggcct ttcctgggga aaccaggcca gctccaccat
    13981 cttcgacagc agccagtcag ccacgccagt gatcgccttt ttaccggcgg cgggcgaagt
    14041 acatctcacc cgtgatgggc ggctactaag cgttcagaac ttcactatgg gcaatcatga
    14101 agtggatacc cggggtctac cgtacgggat ttacgatgtg gaagttgagg tgatcgttaa
    14161 cggtcgcgtg atcagcaaac gcacccagcg ggtcaataag ctgtttagcc gggggcgcgg
    14221 cgtcggtgca ccactggcgt ggcaggtatg gggcggtagc tttcatatgg atcgctggtc
    14281 ggaaaacggg aaaaagacgc gaccagctaa agagagttgg ctagcaggtg cctcgacctc
    14341 cggctcattg agtacgctta gctgggcggc aacgggatat ggatacgata atcaggcggt
    14401 gggt
//
LOCUS       DACAOP010000107        14271 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.107, whole genome shotgun sequence.
ACCESSION   DACAOP010000107 DACAOP010000000
VERSION     DACAOP010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14271
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.107"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(24..620)
                     /gene="slmA"
                     /locus_tag="IT892_003707"
     CDS             complement(24..620)
                     /gene="slmA"
                     /locus_tag="IT892_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion factor SlmA"
                     /protein_id="HAP3136867.1"
                     /translation="MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVS
                     EAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERN
                     PGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLAS
                     QILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ"
     gene            complement(727..1185)
                     /gene="dut"
                     /locus_tag="IT892_003708"
     CDS             complement(727..1185)
                     /gene="dut"
                     /locus_tag="IT892_003708"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAP3136868.1"
                     /translation="MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELA
                     PGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVW
                     NRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ"
     gene            complement(1163..2383)
                     /gene="coaBC"
                     /locus_tag="IT892_003709"
     CDS             complement(1163..2383)
                     /gene="coaBC"
                     /locus_tag="IT892_003709"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418096.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HAP3136869.1"
                     /translation="MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAK
                     AFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARVAAGM
                     ANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGD
                     IGPGRMLDPLTIVDMAVAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGF
                     AIAAAAARRGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAA
                     VADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNV
                     EEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLL
                     LDEIVTRYDEKNRR"
     gene            2555..3223
                     /locus_tag="IT892_003710"
     CDS             2555..3223
                     /locus_tag="IT892_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418095.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAP3136870.1"
                     /translation="MKNNSQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTL
                     AKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLL
                     SPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHCRLFSGTLNHVEVHPREIIREAI
                     KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAE
                     RGWI"
     gene            3440..3676
                     /gene="rpmB"
                     /locus_tag="IT892_003711"
     CDS             3440..3676
                     /gene="rpmB"
                     /locus_tag="IT892_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAP3136871.1"
                     /translation="MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEK
                     RFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY"
     gene            3697..3864
                     /gene="rpmG"
                     /locus_tag="IT892_003712"
     CDS             3697..3864
                     /gene="rpmG"
                     /locus_tag="IT892_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP3136872.1"
                     /translation="MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVR
                     QHVIYKEAKIK"
     gene            3962..4771
                     /gene="mutM"
                     /locus_tag="IT892_003713"
     CDS             3962..4771
                     /gene="mutM"
                     /locus_tag="IT892_003713"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HAP3136873.1"
                     /translation="MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRL
                     SDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMNNGKV
                     LRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMD
                     NKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLK
                     DFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK"
     gene            complement(4810..5289)
                     /gene="coaD"
                     /locus_tag="IT892_003714"
     CDS             complement(4810..5289)
                     /gene="coaD"
                     /locus_tag="IT892_003714"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAP3136874.1"
                     /translation="MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKP
                     MFTLEERVELAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQL
                     AHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA"
     gene            complement(5297..6574)
                     /gene="waaA"
                     /locus_tag="IT892_003715"
     CDS             complement(5297..6574)
                     /gene="waaA"
                     /locus_tag="IT892_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-D-manno-octulosonic acid transferase"
                     /protein_id="HAP3136875.1"
                     /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRH
                     PLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGKDVQ
                     HVYLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSA
                     AGYAKLGKFVRRLLRRITLIAAQNEEDGARFVALGAKNNQVTVTGSLKFDISVTPQLA
                     AKAVTLRRQWAPHRPVWIATSTHEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPD
                     AINLVRQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGH
                     NPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLVKEVSSLLTDADYRS
                     FYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH"
     gene            6981..8051
                     /gene="rfaQ"
                     /locus_tag="IT892_003716"
     CDS             6981..8051
                     /gene="rfaQ"
                     /locus_tag="IT892_003716"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptosyltransferase
                     RfaQ"
                     /protein_id="HAP3136876.1"
                     /translation="MEKPFRKILVIKMRYHGDMLLTTPVISTLKQNYPDAKIDMLLYQ
                     DTIPILSENPEINALYGISNKGTGTFDKIKNALSLIKTLRANNYDLVINLTDQWMVAL
                     LVRCLPARMKISQLYGHRQHGIWKKSFTHLAPIHGTHIVERNLSVLEPLGITDFYTET
                     TMSYAEDCWKKMRQELDALGVKDHYVVIQPTARQIFKCWDNDKFSMVIDALQHRGYQV
                     VLTCGPSADDLACVDEIARGCQTKPITGLAGKTRFPELGALIDHAVLFIGVDSAPGHI
                     AAAVKTPVISLFGATDHVFWRPWTENIIQFWAGNYQKMPTRHELDRNKKYLSVIPAED
                     VIAATEKLLPEDAPSADRNAQL"
     gene            8048..9172
                     /gene="rfaG"
                     /locus_tag="IT892_003717"
     CDS             8048..9172
                     /gene="rfaG"
                     /locus_tag="IT892_003717"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide glucosyltransferase I"
                     /protein_id="HAP3136877.1"
                     /translation="MIVAFCLYKYFPFGGLQRDFMRIASTVAARGHHVRVYTQSWEGD
                     CPEAFELIRVPVKSHTNHGRNAEYYAWVQNHLKAHPADRVVGFNKMPGLDVYFAADVC
                     YAEKVAQEKGFFYRLTSRYRHYAAFERATFEHGKSTKLMMLTDKQIADFQKHYQTEPE
                     RFQILPPGIYPDRKYNAQIPNSREIYRQKNGITEQQNLLLQVGSDFGRKGVDRSIEAL
                     ASLPESLRHNTLLFVVGQDKPRKFEVLAEKLGVRSKVHFFSGRNDVSELMAAADLLMH
                     PAYQEAAGIVLLEAIAAGLPVLTTAVCGYAHYITDANCGTVIAEPFSQEQLNDVLRKA
                     LTQSPLRMAWAENARYYADTQDLYSLPEKAADIITGGLDG"
     gene            9165..9962
                     /gene="rfaP"
                     /locus_tag="IT892_003718"
     CDS             9165..9962
                     /gene="rfaP"
                     /locus_tag="IT892_003718"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(I) kinase RfaP"
                     /protein_id="HAP3136878.1"
                     /translation="MVELEEPLATLWRGKDAFAEVKKLNGEVFRELETRRTLRFELAG
                     KSYFLKWHKGTTLKEIIKNLLSLRMPVLGADREWHAIHRLHDVGVDTMHGIGFGEKGL
                     NPLTRTSFIITEDLTPTISLEDYCADWAVNPPDVHIKRMLIARVATMVRKMHAAGINH
                     RDCYICHFLLHLPFTGREDELKISVIDLHRAQIRAKVPRRWRDKDLIGLYFSSMNIGL
                     TQRDIWRFMKVYFGMPLRDIYRLEIDLLKKARIKAGKIEARTIRKNL"
     gene            9995..10975
                     /locus_tag="IT892_003719"
     CDS             9995..10975
                     /locus_tag="IT892_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP3136879.1"
                     /translation="MLKYRNFVAKKKNLYQNEVSYVKNLHIALCFDREFIMPAGVALY
                     SIISNNRHINLHFHLLISGIEEKECSAFYELEGPNTSISVYYITDKFDINPDTLVLGI
                     PLSTCLRFLIPEVIDDKINKILYLDCDVICNGPLDELVDYNLNADIACVIPDSPEMQE
                     RVKKLDYGIEFINYFNAGVMFINTSEWKKNNITQKALEMINSGKVYRYADQDVLNILL
                     NGRVHYLDKKYNNKTTLSVRCDEEQKNLPNTIIMHYVTQNKPWYKIFRAQNFDHYFSN
                     SPWKNHKRNLAPSSSEIRLKSKVFWLEGKYCKAISYYYKYLLVKLFGLKI"
     gene            10989..12068
                     /gene="waaB"
                     /locus_tag="IT892_003720"
                     /gene_synonym="rfaB"
     CDS             10989..12068
                     /gene="waaB"
                     /locus_tag="IT892_003720"
                     /gene_synonym="rfaB"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,6-galactosyltransferase"
                     /protein_id="HAP3136880.1"
                     /translation="MKIAFIGEAVSGFGGMETVIRDVITTFRQQHIQSEIFFFCRNDK
                     MDKGWLEGIKYSCSFSNIRLGFLRRAKHIHALSKWLHDYQPDVVICIDVISCLYAAKA
                     RKKSGIDVPVFSWPHFSLDHKKHAEYITCADYHLAISSGIKQQMISRGVPESTINVIF
                     NPVEAKNSVIPAPGEGETATFIYVGRMKFEGQKRVKDLLDGLSQVQGDWKLHVLGDGS
                     DFEKCQAYGRELNIDDRIVWYGWQQHPWKLVQQDIKKVSALLLTSSFEGFPMTLLEAL
                     SWGIPCISADCVSGPVDIIQPDVNGHLYQPGDMTGFVALLNKYIAGEIHIAHEKIPAS
                     IDKFYQPKYYDRLQKIIISVISRRK"
     gene            12068..13087
                     /gene="waaO"
                     /locus_tag="IT892_003721"
                     /gene_synonym="rfaI"
     CDS             12068..13087
                     /gene="waaO"
                     /locus_tag="IT892_003721"
                     /gene_synonym="rfaI"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     3-alpha-galactosyltransferase"
                     /protein_id="HAP3136881.1"
                     /translation="MQQVFFQETEFLNSVIDYNHKIEAENLCLDIAYGTDKNFLFGCG
                     ISIASILKYNEGNQLCFHIFTDYFGDDDRKYFDALARQYKTRIKIYLINGDRLRSLPC
                     TKNWTHAIYFRFVIADYFFNKAPKVLYLDADIICQGTIEPLINYTFSEHTVAMVVTEG
                     QKDWWAKRAHSLGVAGIANGYFNSGFLLINTNQWTNERVSARAIAMLSDPEIVKKITH
                     PDQDVLNMLLADKLVYADIKYNTQFSLNYQLKESFKNPVTNDTVFIHYIGPTKPWHDW
                     AWDYPISQAFMAAKNASPWKDTALLKPVNSNQLRYSAKHMLKKKQYIKGFGNYLLYFI
                     KKLKH"
     gene            13251..14267
                     /gene="rfaJ"
                     /locus_tag="IT892_003722"
     CDS             13251..14267
                     /gene="rfaJ"
                     /locus_tag="IT892_003722"
                     /EC_number="2.4.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide glucosyltransferase RfaJ"
                     /protein_id="HAP3136882.1"
                     /translation="MDSFPAIEIDKVKAWDFRLIDENTAESLNVAYGVDSNYLDGVGV
                     SITSIVINNRHVNLDFYIIADVYNDDFFQKVEKLAEQYQLRITLYRINTDNLQCLPCT
                     QVWSRAMYFRLFAFQLLGVTLNRLLYLDADVVCKGNISQLLHLEFNGAVAAVVRDVDP
                     MQEKAVVRLSDPELRGQYFNSGVVYLDLKKWTEAKLTEKALSILMSKDSIYKYPDQDV
                     MNVLLKGMTIFLPREFNTIYTIKSELKDKTHQKYKELIKEDTLLIHYTGATKPWHKWA
                     IYPSVKYYKIALERSPWKDDSPRDAKSIIEFKKRYKHLLVQHHYISGLIAGVCYLCRK
                     YYRK"
BASE COUNT         3984 a         3040 c         3363 g         3884 t
ORIGIN      
        1 atgaaaattc atccggcgtc atattactgc aactgcgcgg caattagcgg ccagcgggcg
       61 tcaaaatcat ccgtcgggcg gtatttaaat tcgctgcgga caaaacgtga cagcatacct
      121 tcacagaagg ccaggatctg gcttgccagc agggtttcat cggtggtgta accttcaccc
      181 tcacgcattc tcttttcacg caatacctgg cgcagctgcg cttcaatacg ctcgaacagc
      241 tggttgatgc gcccttgcag gcgatcctgt tcaaacatta gcgcatgacc agtgaggatg
      301 cgggtcaggc caggattacg ctcaccaaaa ccgagaagca gcaacacaat cagacgcagg
      361 cgcgctgtgg tgtctttctc atctttcaga atcagattga tgcgagtaat caggctatct
      421 tcgataaact caatcaggct atcgaacatg cgggtcttac tggggaagtg gcgatacagt
      481 gccgcttcgg aaacgccgac agaggcggcc agttttgccg tcgtgatacg ttggcttcca
      541 tcgctggatt ccagcatcag cgccagagac tgaagtattt cctcgcgacg gttccttttc
      601 gcagtttgtt tttctgccat gttacaaaat acccctgaaa ataagcactt gccaggcggc
      661 acccacgcta tgaccgcaaa cgaaatgttt gcggctatgt tatgacgtta ttcggatgcg
      721 tatgtgttac tgacgaccag agtgaccaaa gccgccttca ccgcggtcgg tggcgtcgaa
      781 atcttccacc agattaaatt cagcctgtac taccggaaca aaaatcatct gggcgatgcg
      841 ttcgccaggt tgaatggtga agctgtcctg accacggttc cacacggaaa tcatcaactg
      901 gccctgatag tcggaatcga tcaatcctac caggttacca agcacgatac cgtgcttatg
      961 tcccaatccg gagcgcggca gcatcattgc cgccagtgaa ggatcggcaa tatgaatcgc
     1021 cagcccggtc ggaaccagcg tagtgtcacc cggagccagt tctacggcgt cgtcgagaca
     1081 ggcacgcagg tcaagtccgg cagagccaga ggtggcataa gtcgggagcg gaaattcctt
     1141 cccaacgcgc gggtccagaa tcttaacgtc gatttttttc atcataacgg gtcacgatct
     1201 cgtcgagtaa taattggcca aggagctctt tgcgctcaag cggtaagact ttatctccgt
     1261 cctgccagaa aaggtgtaat gcgttgttgt cgctgttaaa tccttgagtt ggctgggaaa
     1321 catcgttcgc gcagatcaga tcaaggtttt tacggatacg tttttgccgg gcgtattctt
     1381 ccacattatt tgtttcggcg gcaaatccaa cgacgtaggg tcgatgatct tttagtgcgg
     1441 caacgcctgc gacgatatcg gggtttttaa ccatttttat tgttaattca tcaccctgcg
     1501 tggcctgctt tttgattttt tctggggcca cggtagctgc gcgataatcc gccacggcgg
     1561 cgcagccgat aaaaatattt tgctgctgta cagaagcatt cacggcggct tccatttcca
     1621 gcgcggtcat cacatcaaca cgtttaacaa acggtggcgt cggtagtgaa accggacctg
     1681 ataccagcgt gacgttcgcg ccacgacggg cagcggcggc ggcgatagca aaacccatct
     1741 tgccggagct gtgattagag atataacgca ccggatcgag cggttcacgc gtcggaccgg
     1801 cggtaatcat aatgttcaga tgtttcaggt cgttgacggg cgaaaaatgc gccaccgcca
     1861 tatccacaat ggttaacgga tcgagcattc gcccaggacc gatatcacca caagcctgac
     1921 tgccactgtc tggcccccag atgagcaaac cacgggaagc aagcacctct aaattatgct
     1981 gcgtggcagc ggcacggtac atctgctggt tcatggcggg gagcacggct acaggcgcag
     2041 gtgtagccag acaaatcgtc gataccaggt cattcgccat tccggcagca acacgggcaa
     2101 tcaaatctgc cgtggcaggg gcgagaatca ctaaatcagc ccatttaccc agctcaatat
     2161 ggcccatagc ggcttcggct gccgggtcca gcaaactgtc ggaaacggga taaccagaaa
     2221 ccgcctgcaa gctaagtggg gtgataaagg cttttgccgc ttcggtcatg gctacgcgga
     2281 cgtcggcccc gcgatcgcgc aaacgacgca ccagttcagg ggttttatag gcagcaatac
     2341 cgccgctaac gccgagaacg atttttttac cggccaggct catgatgatt tttcctgttg
     2401 ggtgacacca gaagttggcg attttatcac aatacttttg ttgtcgtgcc ttcacctgag
     2461 aatcactttg cgaggcgctt tccaggattg aaaactggcc gtcgatttaa cggaacggct
     2521 atgacaggat gcgagcacca caaaggaggt gaaggtgaaa aacaattcac agctgttgat
     2581 gccgcgcgaa aaaatgctga agtttggtat tagcgcctta acggatgtcg agctgctggc
     2641 gctatttctg cgtaccggaa cgcgcggtaa agatgtatta accctggcaa aagagatgct
     2701 ggagaatttc ggctctcttt atggcttgtt aacctctgaa tatgaacaat ttagtggcgt
     2761 tcatggaatt ggcgtggcga aatttgccca gttaaagggg attgctgaac tggcgcggcg
     2821 ttactacaac gtgcggatgc gtgaagaaag ccctttactc agcccggaga tgacgcggga
     2881 atttttacaa agccagctca cgggtgagga gcgggagatc tttatggtga tctttctcga
     2941 ctcacaacac cgggttataa cgcattgccg tcttttttcc ggcacgctaa accatgttga
     3001 agtccatcct cgggaaatta tccgcgaagc gataaaaata aacgcctcgg cgctgatcct
     3061 tgcacataat cacccttcgg gttgtgctga acccagtaaa gcggataaac tcattactga
     3121 acggataata aagagttgtc agttcatgga tttacgcgtg ctcgaccata tcgtgattgg
     3181 gcgtggagag tatgtttctt ttgccgaacg cggttggatt taacccgcta tgcgcgatcc
     3241 ttcgggatct ttgtctgttc gggacttgag cacatcgctg agtcagcgta tactacgcca
     3301 cctttgagaa tctcgggttt ggcatttggg cctggcaatc gagagttcac atagaactgc
     3361 gatgaccggg ctgtaaagcc tgacgaggcg ccaatacccc atacgaagct cgagctaatt
     3421 tgatttttgg agaatagaca tgtcccgagt ctgccaagtt actggcaagc gtccggtgac
     3481 cggtaacaac cgttcccacg cactgaacgc gactaaacgc cgtttcctgc cgaacctgca
     3541 ctctcaccgt ttctgggttg agagcgagaa gcgttttgtc accctgcgcg tatctgctaa
     3601 aggtatgcgt gtaatcgata aaaaaggcat cgatacagtt ctggctgaac tgcgtgcccg
     3661 tggcgaaaag tactaagtac ttagaggaaa taaatcatgg ctaaaggtat tcgtgagaaa
     3721 atcaagctgg tttcttctgc tggtactggt cacttctata ccactacgaa gaacaaacgt
     3781 actaagccgg aaaaactgga actgaaaaaa ttcgatccag ttgttcgcca gcacgtgatc
     3841 tacaaagaag cgaaaatcaa ataattctcg ctttgatgta acaaaaaacc tcgctccggc
     3901 ggggtttttt gttatctgct tgcccccata ttgactgcat ctgttcattc ctggagatgc
     3961 tatgcctgaa ttacccgaag ttgaaaccag ccgccgcggc atagaaccgc atctcgttgg
     4021 tgcaaccatt cttcatgcag tggtgcgcaa cggacgcttg cgctggccgg tttcagaaga
     4081 gatctaccgt ttaagcgacc aaccagtgct tagcgtgcag cggcgggcta aatatctgct
     4141 gctggagctg cctgagggct ggattatcat tcatttaggg atgtctggca gcctgcgcat
     4201 ccttccagaa gaacttcccc ctgaaaagca tgaccatgtg gatttggtga tgaacaacgg
     4261 caaagtgctg cgctacaccg atccgcgccg ctttggtgcc tggctgtgga ccaaagagct
     4321 ggaagggcat aatgtgctgg cccatcttgg accggagccg cttagcgacg atttcaatgg
     4381 tgagtatctg catcagaagt gcgcgaagaa aaaaacggcg atcaaaccgt ggctgatgga
     4441 taacaagctg gtggtaggcg tagggaatat ctatgccagc gaatctctgt ttgcggcggg
     4501 gatccatccg gatcggctgg cgtcatcact gtcgctggcg gagtgcgaat tgctggctcg
     4561 ggtgattaaa gcggtgttgc tgcgttcgat tgagcagggc ggtacaacgc taaaagattt
     4621 tctgcaaagc gacggtaaac cgggctattt cgcgcaggaa ttgcaggttt acgggcgaaa
     4681 aggtgagccg tgtcgggtgt gcggtacgcc gattgtggcg actaaacatg cgcagcgggc
     4741 aacgttttat tgtcggcagt gccagaagta attcatgcgc gccggatggc ataccatccg
     4801 gcataaacgc tacgctaact tcgccatcag cgcctgatgg acattctccg gcaggaaatg
     4861 ggtgacatcg ccctgatggc gcgccacctc tttcaccaac gatgaagaga taaacgacca
     4921 ctctttcgac ggcatcagaa acacactttc cagttccggc attaagtggc gattcatatg
     4981 cgccagctgc atttcatatt caaaatctgc caccgcacgc aggccacgaa tcagcaccgt
     5041 agcgtgttga ttgcgggcga agttcgccat caaatcacta aacccgacca cttccacgtt
     5101 ccccagatgc gcggttgcct gctgtgccag ctccacacgc tcttccaggg taaacatcgg
     5161 ttttttactg gggctggcgg caatcgccag aataacgtga tcgaacattt gcgtggcgcg
     5221 cgtcacgata tcgatatgac cattggtaat gggatcgaaa gtacccggat aaatcgcccg
     5281 tttttgcata acaacctcaa tgcgttttcg gtggcaggta aggttccagc agttgaagca
     5341 gacgctgtag cgcgccctgg ttttgataca gtacttcaac ggcatgacgg ccatagaaac
     5401 tacggtaatc ggcgtcggtg agtaaagagg aaacctcttt tacaagcgta gtggcatcgg
     5461 taacggtaat cagcccgctt gcctgctcca gccgcgcgca aatgtcttta aagttaaaag
     5521 tatgcggccc catcaatacc ggaatagcgt gtgcggcagc ttccagcgga ttatgcccac
     5581 cacgttcaac cagtgaaccg ccaacaaaag cgagatcggc aatgccgtac agtaacatca
     5641 actcgcccat cgtatcgcca accacaacct gcgtgctggt ggaggggact tcccctgaag
     5701 agcgtgtgat atagcttagt ccagcctggc ggacaaggtt aatcgcatcc gggaagcgtt
     5761 ccggatgacg gggtaccagg atgagcaata aattcgggaa ttgctgtaat aatgcctgat
     5821 gtgcggcaat gaccacgctc tcttcacctt cgtgagtgct ggtggcaatc cataccgggc
     5881 ggtgtggtgc ccactggcgg cgcagcgtca ctgctttagc agccagttgc ggcgttacag
     5941 aaatatcgaa tttcaggcta ccggtaacgg tcacctgatt attttttgcg cccagcgcca
     6001 caaaacgtgc accatcttct tcattttggg cggcaatcag cgtaatacga cgcagcaagc
     6061 gacggacgaa tttacccagt ttggcataac ctgcggccga gcgggcagag agtcgcgcgt
     6121 tagcgatcac cagcggaatt ttacgtttat gtagcgccgc aatcaggtta ggccatagtt
     6181 cggtttccat aatcaacacc agtttagggt cgactttatt caggaaacga ttaagtgcat
     6241 cgggcaggtc atatggcaga taaacgtgct gaacatcctt cccgaaagcc gattgtacgc
     6301 gctccgaacc ggttggtgtc atggttgtaa cggtaatcgg taaatcagga taacgatgac
     6361 gcagcgcgcg caccaatggg atcgccgcca gagtttcacc gacggagacg gagtgcagca
     6421 taatgccgcc tggttttagc ggatggcggt aaaaaccgta acgttcaccc cagcgttttc
     6481 gataggccgg agccttacgt ccgcgcaccc agagccgtat ccagatcagc ggctgaataa
     6541 ggtagagaag ggcggtgtaa agcaattcaa gcataataaa tagctgactt atggatgtgc
     6601 tggggattct atgtatttag caccgggttt gccattactt ttcctttttt tgacttaatt
     6661 agcctctgtt tgagctgatc tgccgctaga tcttcatttt ttttgtattt ttatgcgatt
     6721 cattgaattt cagccaggat tgcagcttta catcgacaat atctggattc tcgagtatgc
     6781 aaaattttat ctctatgatt tttataatta aaacatattt tgtgtataaa aatcattcgg
     6841 gtcggattgc tgcgaaagaa atgatacact agcgcgtcaa agtaagtgcg ttatcagtat
     6901 tcgggtagct gttgagcctg gggcggtagc gtgctttttt ctgcttaact taaccagaca
     6961 atcacacaaa agagtcgcta gtggaaaagc catttcgaaa aatcctggtc ataaagatgc
     7021 gatatcacgg agatatgtta ttaactactc ctgtaatcag tacactcaag cagaattatc
     7081 ccgacgcaaa aatcgatatg ctgctttacc aggatacaat tccgatttta tctgaaaacc
     7141 cagaaattaa tgcactctat ggtataagca ataaaggtac gggaacattc gataaaatta
     7201 aaaatgcact ttcactgata aaaactctgc gtgcgaataa ttacgacctg gtcattaatc
     7261 ttacggatca gtggatggtg gccctgctgg tacgttgttt acctgctcgt atgaaaatat
     7321 cgcagcttta tggtcatcgg cagcatggca tttggaaaaa aagctttaca cacttagcgc
     7381 ctatacacgg tacacatatt gttgagcgta atttgtcggt ccttgagcca ttaggtatta
     7441 ccgattttta tactgaaaca accatgagtt acgccgagga ttgctggaag aaaatgcgcc
     7501 aggaattaga tgcactgggc gtgaaagatc attatgtcgt catccagccg acagccagac
     7561 agatatttaa gtgctgggac aacgataaat tttctatggt tatcgatgcg ttgcaacatc
     7621 gtggttatca ggttgtgctg acttgtggcc cttcggcaga tgatctcgct tgcgtagatg
     7681 aaattgcacg aggctgccaa acaaaaccta ttaccggcct tgccggtaaa acacgttttc
     7741 ctgaactggg cgcattaatt gatcatgcag tgctctttat tggtgtggat tctgcgccgg
     7801 ggcatattgc agcggctgtg aagacgccag ttattagcct gtttggggcc actgatcatg
     7861 tattctggcg tccatggacc gagaatatta ttcagttctg ggcggggaat tatcaaaaaa
     7921 tgcctacccg gcacgaactt gaccgcaaca aaaaatatct ttctgttatt ccagcggaag
     7981 atgtcattgc cgctacggaa aagctgttgc cagaagatgc accttcagct gacaggaatg
     8041 cgcaattatg atcgtggcat tttgcttata taaatatttt ccatttggtg ggctacagcg
     8101 tgactttatg cgtattgcct caacagttgc cgcacggggc caccatgttc gggtatatac
     8161 acagtcgtgg gaaggcgatt gcccggaagc atttgagctt attcgcgtac cggttaaatc
     8221 ccatactaac catggacgta atgcagaata ttatgcctgg gttcaaaacc atctgaaggc
     8281 acatcccgct gatcgcgttg ttggctttaa taagatgcct gggctggatg tttattttgc
     8341 cgccgatgtc tgttatgccg agaaagtggc gcaagaaaag ggatttttct atcgtttaac
     8401 atcgcgctat cgccattatg ctgcattcga gcgagcgact ttcgaacatg gtaaatcgac
     8461 gaaacttatg atgttgaccg ataagcaaat cgccgatttt cagaagcatt accaaactga
     8521 accagaacgt tttcaaattc ttccccctgg tatctatcct gacagaaaat acaacgcgca
     8581 aatcccaaac agtcgtgaaa tttatcgcca gaaaaatggc atcactgaac aacaaaactt
     8641 attgctgcag gttggttcag attttggtcg taaaggtgtg gatcgctcaa ttgaagcttt
     8701 ggcatcgtta ccagaatcgt tacgccataa tacgttgttg tttgttgttg gccaggataa
     8761 accgcgtaaa tttgaagtgc tggcagaaaa actcggtgtg cgtagtaaag tgcatttctt
     8821 ttccgggcgg aatgatgtgt ctgaattaat ggcagccgct gatttattaa tgcatcccgc
     8881 ttatcaggag gctgcaggta ttgttctcct tgaggcaatt gccgcgggat tacctgtgtt
     8941 gacgactgcg gtatgcggat acgcacacta tatcacagat gctaattgtg gaacggtcat
     9001 cgctgaacct ttctcccagg aacaattaaa tgacgtttta cgtaaagcgt taactcaatc
     9061 tccattgcgc atggcctggg cggagaatgc tcggtattac gccgatactc aggatttata
     9121 cagcctgccg gagaaagcgg cagatatcat tacaggtggt ttagatggtt gaattagaag
     9181 agccacttgc cacactctgg cgtggtaaag atgcctttgc agaagttaaa aaactgaatg
     9241 gcgaggtctt ccgtgaactg gagacgcgtc gcacattacg ctttgaactg gccggcaaaa
     9301 gttatttcct caaatggcac aaagggacga ccctaaagga gattataaaa aatctgctct
     9361 cattgcggat gcccgtttta ggtgcagaca gagagtggca cgctattcat cgactgcatg
     9421 atgtcggtgt tgatacgatg cacggaatag gatttggtga aaaagggtta aatccattaa
     9481 ctcgcacatc atttattatt accgaagatc tcactcccac aattagcctt gaagattatt
     9541 gtgcagattg ggcggtcaac ccgcctgatg tacatattaa gcgtatgctg atcgcgcgtg
     9601 tggcaaccat ggtgcgcaaa atgcatgcag cagggattaa tcaccgtgat tgttatatct
     9661 gccacttttt actccatttg ccatttactg gccgggaaga tgaattaaaa atttcggtta
     9721 tcgatctgca ccgggcacag atacgtgcaa aagtaccacg tcgttggcgg gataaagatt
     9781 tgattggttt atatttctca tcaatgaata ttggtctgac gcagagagat atctggcgat
     9841 ttatgaaggt ttattttggg atgcctttac gcgatattta tagacttgag attgatttac
     9901 ttaaaaaggc aaggattaaa gcaggaaaaa tagaagcaag aacaataaga aaaaacttgt
     9961 aaatagtatt ttattacaaa aagggattct aaaattgttg aaatatagaa acttcgttgc
    10021 taagaagaaa aatttatacc aaaacgaagt gtcgtatgtt aaaaatttac atattgcact
    10081 atgctttgac cgtgaattca taatgccagc gggtgttgca ttatattcaa ttatatccaa
    10141 caatagacat attaaccttc attttcacct tcttatatca ggcatagaag aaaaggagtg
    10201 ttcagctttt tacgaactag aaggtcctaa tacatcaata tctgtatatt atataactga
    10261 taaatttgac attaatccgg atacattagt tcttggtatt cctttatcaa catgtttacg
    10321 ttttttaatc ccagaagtta ttgatgataa aataaataag atactttatc ttgactgtga
    10381 tgtcatatgt aatggtcctt tagatgaact ggttgattat aatttaaatg ctgatattgc
    10441 atgtgtaatt ccagattcgc cagaaatgca agaacgtgta aaaaaattag actatggcat
    10501 tgagtttatt aattatttta atgccggggt tatgtttatt aataccagcg aatggaaaaa
    10561 aaataatata acacaaaaag cgttagaaat gatcaacagt ggaaaagtat ataggtatgc
    10621 agatcaggat gtgctcaata ttttacttaa tggacgagtg cattaccttg ataagaagta
    10681 caataataag acaacattgt cagtacgatg tgatgaagaa caaaaaaact tgcccaacac
    10741 aattataatg cattatgtta cccagaataa accatggtac aaaatattta gagcacaaaa
    10801 ttttgatcat tatttttcaa attctccttg gaagaaccat aaaagaaatc tagctccatc
    10861 atcaagtgag attaggttaa agtctaaagt tttttggcta gaaggaaaat attgtaaagc
    10921 catttcttat tattataagt atttacttgt taaattattt ggcttaaaga tttagctgga
    10981 atgaaattat gaaaatagcc tttattggcg aagctgtttc tggatttggc ggcatggaaa
    11041 cagtcattcg tgatgttatt actaccttca ggcaacaaca tatccaaagt gaaatttttt
    11101 tcttttgtcg taatgacaaa atggataagg gatggctgga aggtattaag tactcgtgtt
    11161 cattttccaa tattcgctta ggttttttgc gtcgcgcgaa acatattcat gctttaagca
    11221 aatggcttca tgattatcag ccagatgttg ttatttgtat tgacgtgatc tcgtgtttgt
    11281 atgcggccaa agctcgtaaa aaatcgggga ttgatgtacc tgtattttca tggccgcatt
    11341 tttctttaga tcataaaaaa catgccgaat atatcacctg tgccgactat catttagcca
    11401 tcagctctgg tattaaacag caaatgatta gccggggtgt accagaatcg acaataaacg
    11461 ttatttttaa tcccgttgag gcgaaaaatt cagtcattcc tgcacccggg gaaggcgaaa
    11521 cggcaacatt catttatgtt gggcgcatga aatttgaagg ccaaaagcgc gtaaaagatc
    11581 tgcttgatgg cttatcacaa gtgcaaggtg actggaaact tcatgtattg ggagatggct
    11641 ccgatttcga aaaatgccag gcttatggta gagaattaaa tattgatgat cgaattgtct
    11701 ggtatggttg gcaacaacat ccctggaaat tagttcagca agatattaaa aaagtgagtg
    11761 cattattact cacgtcatct tttgaaggtt tcccaatgac tctacttgaa gccttgtcgt
    11821 gggggatccc ttgtatcagt gcagattgtg tctccgggcc tgttgatatc attcagcctg
    11881 atgttaatgg tcatttatat caaccggggg atatgaccgg ttttgttgct cttctcaata
    11941 aatacatagc cggtgaaatt cacatcgcac atgaaaaaat tccggcgtcg atcgataaat
    12001 tttatcaacc gaaatattac gacagattgc aaaagataat tatttctgtt atttcccgga
    12061 ggaaataatg cagcaggttt ttttccagga gactgagttt ctcaattcgg ttattgatta
    12121 taatcataaa atagaagcag aaaatctttg tctggatatt gcttatggga ctgacaaaaa
    12181 ttttcttttt ggatgcggaa tatcgattgc ttcaatatta aaatataatg aaggaaatca
    12241 attatgcttt catattttta ctgattattt cggtgatgac gatcgcaaat attttgatgc
    12301 cctggccagg caatataaaa caagaattaa gatatattta attaatggtg atcgactccg
    12361 ttcattaccc tgcaccaaga actggactca tgctatttat tttcgttttg ttatcgccga
    12421 ttactttttt aataaagcac ccaaagttct ttatctggat gcagatatta tttgtcaggg
    12481 aactatagaa ccacttatca attacacgtt ttctgaacat acagtcgcaa tggttgttac
    12541 agaaggacaa aaagactggt gggcaaaacg tgctcattcg ttaggtgttg ctgggattgc
    12601 taatggttac tttaactccg gttttttact gattaatact aatcaatgga cgaatgagcg
    12661 ggtttctgca cgggccattg caatgttaag tgatccagag atagtcaaaa aaataacaca
    12721 tcctgatcag gatgtattaa atatgttatt ggcagacaaa cttgtttatg ctgatattaa
    12781 atataacact cagtttagtt taaattatca actaaaagaa agttttaaaa acccagtaac
    12841 taacgataca gtttttattc attatattgg tccaactaaa ccctggcatg actgggcctg
    12901 ggattatcca atatcacaag cttttatggc ggcaaaaaat gcttcaccat ggaaggatac
    12961 tgcgttattg aaaccggtta atagtaatca attaagatac agtgctaaac atatgttgaa
    13021 aaaaaagcaa tatatcaaag gatttggcaa ctatcttttg tattttataa aaaagctaaa
    13081 gcattaatac tgataatcta tactctaaat aattcgagtt gcaggacaaa aagccagtgg
    13141 cgttttgagg aacgcttgcg ttggccctga aatgccgagt aactcgccga tgcagcacat
    13201 gcaacttgaa gtataacgag tatataaagt aatgatataa ggatagcctt gtggactcat
    13261 ttcctgccat agagatagat aaagttaaag cctgggattt taggcttatt gatgaaaata
    13321 ctgctgaaag tttaaatgtt gcctatggtg tcgattccaa ttatcttgat ggtgtaggtg
    13381 tttccattac ttcaattgtc attaataatc gacatgttaa tcttgatttt tatattattg
    13441 ctgatgttta taacgacgat ttctttcaaa aagttgagaa acttgctgag caataccaat
    13501 taagaatcac actttataga ataaatactg ataatcttca gtgcctgcct tgtacacaag
    13561 tctggtcaag agcaatgtac ttccgtttat ttgcttttca attattggga gtaacactta
    13621 atcgtttgct ttatcttgat gccgatgtag tttgtaaggg aaatattagt caactattgc
    13681 atttagagtt taatggagcg gtggctgcag tagtcaggga tgtagaccca atgcaggaaa
    13741 aggcggtagt cagattatct gatcctgaac ttcgggggca gtattttaat tctggtgtcg
    13801 tttacttaga cctaaaaaaa tggacagaag caaaactaac cgaaaaagca ctgtctattc
    13861 ttatgagtaa agatagtatt tataagtatc ctgaccagga cgttatgaat gtcctactaa
    13921 aagggatgac aatattcctg ccacgtgagt tcaatactat atatacaata aaaagtgagt
    13981 taaaagataa aacgcatcaa aaatataaag agttgataaa agaggatact cttcttattc
    14041 attatactgg ggccaccaag ccgtggcaca aatgggcaat ttatccatcg gtaaaatact
    14101 ataaaatagc tttagaaaga tccccctgga aagatgactc accacgagat gcaaaatcaa
    14161 ttattgaatt caaaaaaaga tataaacatc tgttagtgca acatcattat atctcaggac
    14221 tcattgcagg agtgtgttat ctttgccgaa aatattaccg taaataacat t
//
LOCUS       DACAOP010000108        14253 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.108, whole genome shotgun sequence.
ACCESSION   DACAOP010000108 DACAOP010000000
VERSION     DACAOP010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14253
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.108"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..668)
                     /locus_tag="IT892_003723"
     CDS             complement(<1..668)
                     /locus_tag="IT892_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP3136883.1"
                     /translation="MNNREKEILAILRRNPLIQQNEIADMLQISRSRVAAHIMDLMRK
                     GRIKGKGYILTEQEYCVVVGTINMDIRGMADIRYPQAASHPGTIHCSAGGVGRNIAHN
                     LALLGRDVHLLSVIGDDFYGEMILEETRRAGVNVSGCVRLHGQSTSTYLAIANRDDQT
                     VLAINDTHLLEQLTPQLLNGSRDLLRHAGVVLADCNLTAEALEWVFTLADEIPVFVDT
                     VSEF"
     gene            complement(671..1528)
                     /gene="nfo"
                     /locus_tag="IT892_003724"
     CDS             complement(671..1528)
                     /gene="nfo"
                     /locus_tag="IT892_003724"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAP3136884.1"
                     /translation="MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPL
                     TTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLG
                     LSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEH
                     LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLN
                     DAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLK
                     AQQTEKAVA"
     gene            complement(1602..2651)
                     /locus_tag="IT892_003725"
     CDS             complement(1602..2651)
                     /locus_tag="IT892_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HAP3136885.1"
                     /translation="MTNITLQKQHRTLWHFIPGLALSAVITGVALWGGSIPAVAGAGF
                     SALTLAILLGMVLGNTIYPHIWKSCDGGVLFAKQYLLRLGIILYGFRLTFSQIADVGI
                     SGIIIDVLTLSSTFLLACFLGQKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEA
                     SKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPETFGIYIGSTVHEVAQVVAAGHAI
                     SPDAENAAVISKMLRVMMLAPFLILLAARVKQLSGANSGEKSKITIPWFAILFIVVAI
                     FNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGAKPLLMALVLFAWLI
                     VGGGAINYVIQSVIA"
     gene            2750..3631
                     /locus_tag="IT892_003726"
     CDS             2750..3631
                     /locus_tag="IT892_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3136886.1"
                     /translation="MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQ
                     LGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRIYASSTIGNY
                     ILPAVIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLE
                     DELVVFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMEL
                     GNSEAIKHAVRHGLGISCLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLS
                     NALRRFLDYCDPANVPR"
     gene            3836..5305
                     /gene="lysP"
                     /locus_tag="IT892_003727"
     CDS             3836..5305
                     /gene="lysP"
                     /locus_tag="IT892_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-specific permease"
                     /protein_id="HAP3136887.1"
                     /translation="MVSETKTTEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATIS
                     QAGPGGALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNY
                     WYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFS
                     LIKVTTVIVFIIVGVLMIIGIFKGAQPAGWSNWTIGEAPFAGGFAAMIGVAMIVGFSF
                     QGTELIGIAAGESEDPAKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPSLLRNDV
                     KDISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPR
                     IFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAIS
                     HYRFRRGYVLQGHDINDLPYRSGFFPLGPIFAFILCLIITLGQNYEAFLKDTIDWGGV
                     AATYIGIPLFLIIWFGYKLIKGTHFVRYSEMKFPQNDKK"
     gene            5599..7590
                     /gene="cirA"
                     /locus_tag="IT892_003728"
     CDS             5599..7590
                     /gene="cirA"
                     /locus_tag="IT892_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor CirA"
                     /protein_id="HAP3136888.1"
                     /translation="MFRLNPFVRVGLCLSAISCAWPVLAVDDDGETMVVTASSVEQNL
                     KDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLIL
                     VDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVVNIITKKI
                     GQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDDPQNS
                     TTTDTGETPRIEGFSSRDGNVEFAWTPNQNHDFTAGYGFDRQDRDSDSLDKNRLERQN
                     YSVSHNGRWDYGTSELKYYGEKVENKNPGNSSPITSESNTVDGKYTLPLTAINQFLTV
                     GGEWRHDKLSDAVNLTGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGE
                     HWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIVGSPDLKPE
                     TSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRTSDVNAAPGYQNFVGFET
                     GANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYTYNDGRDVSNGENKPLS
                     DLPFHTANGTLDWKPLALEDWSFYVSGHYTGQKRADSATAKTPGGYTIWNTGAAWQVT
                     KDVKLRAGVLNLGDKDLSRDDYSYNEDGRRYFMAVDYRF"
     gene            complement(7622..8458)
                     /gene="yeiG"
                     /locus_tag="IT892_003729"
     CDS             complement(7622..8458)
                     /gene="yeiG"
                     /locus_tag="IT892_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HAP3136889.1"
                     /translation="MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPP
                     VLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEKVANDDGYDLGQGAGF
                     YLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPG
                     KYTSVSAFAPIVNPCSVPWGIKAFSSYLGEDKNAWLEWDSCALMYASNAQDAIPTLID
                     QGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYL
                     LK"
     gene            8716..9384
                     /gene="folE"
                     /locus_tag="IT892_003730"
     CDS             8716..9384
                     /gene="folE"
                     /locus_tag="IT892_003730"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HAP3136890.1"
                     /translation="MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHM
                     TEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTV
                     RDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
                     IALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAV
                     RHHN"
     gene            9401..10558
                     /locus_tag="IT892_003731"
     CDS             9401..10558
                     /locus_tag="IT892_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 family protein"
                     /protein_id="HAP3136891.1"
                     /translation="MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITP
                     QDAWTWAFLDLVGQVKFLTLFALLFGAGLQMLLPRGRRWIQSRLTLLVLLGFIHGLLF
                     WDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRA
                     WTPDASAILYEKYWKLHGGVDAISNRADGVGNSLLALGAQYGWQLAGMMLIGAALMRS
                     GWLKGQFSLRHYRRTGFVLVAIGVIINLPAIALQWRLDWAYRWCAFLLQMPRELSAPF
                     QAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLGLFMHFDR
                     LELLAFVIPVWLANILFSVIWLRFFRQGPVEWLWRQLTLRAAGPAISKTSR"
     gene            10700..11740
                     /gene="galS"
                     /locus_tag="IT892_003732"
     CDS             10700..11740
                     /gene="galS"
                     /locus_tag="IT892_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalS"
                     /protein_id="HAP3136892.1"
                     /translation="MITIRDVARQAGVSVATVSRVLNNSTLVSADTREAVMKAVSELD
                     YRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAE
                     KERHAIEVLIRQRCNALIVHSKALSDDELAQFMDNIPGMVLINRVVPGYAHRCVCLDN
                     LSGARMATRMLLNNGHQRIGYLSSSHGIEDDAMRKAGWMSALKEQDIIPPESWIGTGT
                     PDMPGGEAAMVELLGRNLQLTAVFAYNDNMAAGALTALKDNGIAIPLHLSIIGFDDIP
                     IARYTDPQLTTVRYPIASMAKLATELALQGAAGNIDPRASHCFMPTLVRRHSVATRQN
                     AAAITNSTNQAM"
     gene            12020..13018
                     /gene="mglB"
                     /locus_tag="IT892_003733"
     CDS             12020..13018
                     /gene="mglB"
                     /locus_tag="IT892_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/glucose ABC transporter
                     substrate-binding protein MglB"
                     /protein_id="HAP3136893.1"
                     /translation="MNKKVLTLSAVMASMLFGAAAHAADTRIGVTIYKYDDNFMSVVR
                     KAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEK
                     ARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNK
                     DGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAW
                     LSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGALAGT
                     VLNDANNQAKATFDLAKNLADGKGAADGTNWKIDNKVVRVPYVGVDKDNLAEFSKK"
     gene            13079..>14253
                     /locus_tag="IT892_003734"
     CDS             13079..>14253
                     /locus_tag="IT892_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP3136894.1"
                     /translation="MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHAL
                     MGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQ
                     RSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
                     AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDE
                     VTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQ
                     PSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKQINNHNANE
                     AINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDS
                     "
BASE COUNT         3447 a         3526 c         3782 g         3498 t
ORIGIN      
        1 ttgaattctg aaacggtatc gacaaacacc gggatttcat cagcgagggt aaagacccat
       61 tccagcgcct cggctgtcag gttgcaatca gccagtacca cgcccgcatg acgaagtaaa
      121 tcgcgcgacc cgttcagtag ttgcggtgtc aactgttcca gcagatgggt atcgttaatc
      181 gccagcacgg tttgatcgtc tcgattggca attgccagat acgtcgatgt gctttgacca
      241 tgcaaacgaa cgcagccgga gacattcacg ccggcacggc gcgtttcttc caggatcatt
      301 tcgccataaa agtcatcgcc aatcactgaa agcaaatgga cgtcacggcc taacagcgcc
      361 agattgtggg cgatgttgcg tcccacgccg cccgccgagc aatgaattgt accgggatga
      421 gaagccgctt gcgggtaacg gatatccgcc atcccgcgaa tatccatatt gattgtcccc
      481 accactacgc agtattcctg ctcggtgaga atgtaacctt tgcctttaat ccgccctttg
      541 cgcattaaat ccataatatg cgccgcaacg cgcgaacgac tgatttgcag catgtccgca
      601 atttcgttct gctgaatcag cgggttacgc cgtaaaattg caaggatctc cttttcccgg
      661 ttattcatct tcaggctacc gctttttcag tttgttgcgc tttcagccag gcgatctctt
      721 ctgcccagat atccgggttg atggtttcaa ggatcagcgg aatgccgtcg aaacggtcgt
      781 cctgcatgat ccagcggaac gcatcatgac cgatattgcc ttcaccgagg ctatgatggc
      841 ggtcaacgcg gctgccaaag gtgcttttcg catcgttaag gtgcatcccg cgcagatact
      901 taaagccaac aatacgggca aaatccgcga acgttttctc gcattcggct ggagtacgca
      961 aatcataccc ggcagcgaaa gcatggcagg tatcaatgca gacgccgaca cgggatttat
     1021 cttccacgcc gtcgataatc gccgcgagat gttcgaattt aaaccctaag ttactgccct
     1081 gaccggcggt gttttcaatc accgctgtta caccttgagt tttatccagc gcaatgttga
     1141 tggattcggc aatacgcgca aggcaatcct cttctgaaat ctgcatcaga tggctgccag
     1201 ggtggaagtt gagcaaagaa agccccagtt gttcgcaacg ctgcatttca tctataaagg
     1261 catcgcgcga tttttccaga gcttcagtga ccggatgtcc gaggttaatc agatagctgt
     1321 cgtggggaag aatttgcgcc gatgtgtagt gatatttttc acaggccgct ttgaattcat
     1381 cgatggtttg cgtcgtgagc ggtgcggcac gccactgacg ttggtttttg gtgaacaagg
     1441 caaacgcggt tgcgtcgatt tcggcggcgc gaattgcggc atttgccaga ccgccagcag
     1501 cactaacgtg cgctccaatg tatttcatgc gaggactcct gttaaacccg ctggaggaaa
     1561 acggtaatga tagcgggtta acaggagcaa gatgtagtgg tttatgcgat gacgctttga
     1621 atcacatagt taatcgcacc accaccaaca atcagccagg caaacagtac cagtgccatc
     1681 agcagaggtt tcgccccggc ttttttcagc gcgctgacgt gagtggtcag acccagcgcc
     1741 gccatcgcca ttgccagcag gaaggtatcc agcgttacca gcatgttcac cacgctctgc
     1801 ggtaacaggt ggaacgagtt aaagatggca acgacgatga acaagatggc aaaccacgga
     1861 atagtgattt tgcttttctc gccgctgttc gccccagaca gctgtttaac acgcgccgcc
     1921 agcaggatga ggaacggagc cagcatcatc acgcgcagca ttttggaaat aactgctgcg
     1981 ttttccgcat ccgggctgat agcatgacct gccgccacca cctgcgccac ttcgtgcaca
     2041 gtagaaccaa tgtagatacc gaaagtttcc ggactaaacc attgagacat cagcggatat
     2101 atcgccgggt agaggaaaat cgcgacggtc ccgaagataa caacggttgc aacagccacg
     2161 gttactttac tggcttccgc tttcactacc ggctcagtcg ccagtaccgc ggcagcacca
     2221 cagatactgc taccggcacc gatcaaccag ctggtgtgct tatccagacc aaacactttc
     2281 tgccccagga agcaagccag caggaaggta ctggacagcg tcaacacgtc aatgatgatc
     2341 ccactgatac cgacatcggc aatttgcgag aacgtcagac ggaagccata aagaatgata
     2401 cccagacgta ataaatattg cttggcaaac agcacaccac cgtcacagct tttccagatg
     2461 tgcggataga tggtgttgcc taaaaccatc cccaacaaga ttgcgagggt gagggcacta
     2521 aacccggcac ccgcaaccgc gggaatggaa ccaccccaca gggcgacccc ggtgataact
     2581 gcactcaggg ctaaccccgg aataaaatgc cacagtgtac gatgttgttt ctgtaaggtg
     2641 atattcgtca taaccctctc ctttaaccgg gcataaggtt acgactaact ggtttaaaaa
     2701 taaaattgat tatatattta taattaatct ttataagtgg taagcgacta tgcacatcac
     2761 cctccggcag ttggaagttt ttgcagaagt attgaaaagt ggatcaacca cccaggcgtc
     2821 ggtgatgctg gcgttgtcgc aatcagcagt gagcgcagcc ttgaccgacc tggaagggca
     2881 gcttggcgtg caactgtttg atcgcgtggg gaaaagactg gttgttaatg aacacgggcg
     2941 gctgctctat ccgcgtgcgt tggcattgct tgaacaggcg gttgaaatcg aacaactgtt
     3001 tcgcgaagac aacggcgcga ttcgtatcta tgccagtagt accatcggta actacattct
     3061 gcctgcagtt atcgcccgtt atcgccatga ttatccgcag ttgccgattg aacttagcgt
     3121 tgggaatagc caggacgtga tgcaagcggt gctggatttc cgcgttgata ttggctttat
     3181 tgaaggaccg tgccacagca ctgaaatcat ttctgaaccg tggctggaag acgagctggt
     3241 ggttttcgcc gcgccgactt cgccgttggc ccgtggtccg gtcaccttag aacagctggc
     3301 cgctgcgccg tggatcctgc gtgaacgcgg ttccggcacg cgggagattg tcgattatct
     3361 gttgctgtca catttaccga agtttgagat ggcgatggaa ttaggtaact ccgaggcaat
     3421 caaacatgcg gtgcgtcatg ggttgggaat tagttgcctg tcgcgacgtg tgattgaaga
     3481 tcaattgcag gcaggcacat taagtgaagt tgcggtccct ctgccgcgcc tgatgcgtac
     3541 gttgtggcgt atacatcatc ggcaaaaaca cctttccaac gcgctacggc gctttctgga
     3601 ctattgcgat cccgcaaatg tgccgcgtta agttgctgta caagaacatg ctggtgctgt
     3661 gtcgatttcg tgacgcagcg ccttcagcat gcattcgcca gaaaagagat tggctgcttt
     3721 acttataatc cctgggcgat catgaaggtg tcttataacc gtgtatttct gccggaagga
     3781 ttgccaatcg tctgctacaa tcgcgcctca tttttaagat ggatagcatt tttgtatggt
     3841 ttccgaaact aaaaccacag aagcgccggg cttacgccgt gaattaaagg cgcggcacct
     3901 gacgatgatt gccattggcg gttccatcgg tacaggtctt tttgttgcct ctggcgcaac
     3961 gatttctcag gcaggtccgg gcggggcatt gctctcgtat atgctgattg gcctgatggt
     4021 ttacttcctg atgaccagtc tcggtgaact ggctgcatat atgccggttt ccggttcgtt
     4081 tgccacttac ggtcagaact atgttgaaga aggctttggc ttcgcgctgg gctggaacta
     4141 ctggtacaac tgggcggtga ctatcgccgt tgacctggtt gcagctcagc tggtcatgag
     4201 ctggtggttc ccggatacac cgggctggat ctggagtgcg ttgttcctcg gcgttatctt
     4261 cctgctgaac tacatctcag ttcgtggctt tggtgaagcg gaatactggt tctcactgat
     4321 caaagtcacg acagttattg tctttatcat cgttggcgtg ctgatgatta tcggtatctt
     4381 caaaggcgcg cagcctgcgg gctggagcaa ctggacaatc ggcgaagcgc cgtttgctgg
     4441 tggttttgcg gcgatgatcg gcgtagctat gattgtcggc ttctctttcc agggaaccga
     4501 gctgatcggt attgctgcag gcgagtccga agatccggcg aaaaacattc cacgcgcggt
     4561 acgtcaggtg ttctggcgaa tcctgttgtt ctatgtgttc gcgatcctga ttatcagcct
     4621 gattattccg tacaccgatc cgagcctgct gcgtaacgat gttaaagaca tcagcgttag
     4681 tccgttcacc ctggtgttcc agcacgcggg tctgctctct gcggcggcgg tgatgaacgc
     4741 agttattctg acggcggtgc tgtcagcggg taactccggt atgtatgcgt ctactcgtat
     4801 gctgtacacc ctggcgtgtg acggtaaagc gccgcgcatt ttcgctaaac tgtcgcgtgg
     4861 tggcgtgccg cgtaatgcgc tgtatgcgac gacggtgatt gccggtctgt gcttcctgac
     4921 ctccatgttt ggcaaccaga cggtatacct gtggctgctg aacacctccg ggatgacggg
     4981 ttttatcgcc tggctgggga ttgccattag ccactatcgc ttccgtcgcg gttacgtatt
     5041 gcagggacac gacattaacg atctgccgta ccgttcaggt ttcttcccac tggggccgat
     5101 cttcgcattc attctgtgtc tgattatcac tttgggccag aactacgaag cgttcctgaa
     5161 agatactatt gactggggcg gcgttgcggc aacgtatatt ggtatcccgc tgttcctgat
     5221 tatttggttc ggctacaagc tgattaaagg aactcacttc gtacgctaca gcgaaatgaa
     5281 gttcccgcag aacgataaga aataagtttc ctcccttcct tgctaagccc tctcaaccga
     5341 gagggctttt tcaattccat ttccctgaca aatcatgcgg atataaaatt taacatttgg
     5401 attgataatt gttatcgttt gcattatcgt tacgccgcaa tcaaaaaagg ctgacaaatc
     5461 agaggctgtt ccggctttct gggatgatca cctgcataaa aaataagtcc accgcgatgc
     5521 tgccgtacgc aaggggacgt gaagaagatg tgagcgataa cccattttat tttcgtagtt
     5581 acctcatgga gatatggaat gtttaggttg aaccctttcg tacgggtcgg gctgtgtttg
     5641 tccgctattt cttgtgcatg gcctgtgtta gcggtcgatg atgatggcga aacgatggtt
     5701 gtcactgcat cttccgtgga acaaaatctt aaagatgcac ctgccagtat cagcgtcatt
     5761 acccaggaag acctgcagcg aaaaccggta cagaatctga aggatgtcct caaagaagtg
     5821 cctggcgtac aactgacgaa cgaaggggat aaccgtaagg gcgttagtat tcgtggtctg
     5881 gacagcagct ataccctgat tctcgtcgac ggtaaacgcg tgaactcccg caatgccgtc
     5941 ttccgccaca atgatttcga tctgaactgg atcccggtcg attccatcga acgtattgaa
     6001 gtggtccgtg gcccgatgtc gtcgctgtac ggttccgatg cgctcggcgg tgtagtgaat
     6061 atcatcacca aaaaaatcgg tcagaaatgg tcgggtaccg ttaccgtcga taccaccatt
     6121 caggaacatc gcgatcgcgg tgacacctat aacggtcagt tctttaccag tggaccatta
     6181 attgatggtg tgctgggaat gaaagcttac ggcagcctgg caaaacgtga aaaggatgac
     6241 ccgcaaaact caacgaccac cgataccgga gaaacgccgc gtattgaagg attctccagc
     6301 cgcgacggca atgtcgaatt tgcctggaca ccgaatcaaa atcacgattt tactgccgga
     6361 tacggtttcg accgtcagga tcgtgattcc gactcgctgg acaaaaaccg cctggaacgc
     6421 cagaactact ccgtcagcca taatgggcgt tgggattacg gcaccagcga actgaaatac
     6481 tacggtgaga aagtcgagaa caaaaaccct ggcaacagca gcccgataac ttccgaaagc
     6541 aatacggtcg acggcaaata cacgttgccg ctgacggcga ttaatcagtt tctcacggtt
     6601 ggcggtgaat ggcgtcacga caaacttagc gatgcggtga acctgaccgg gggaaccagc
     6661 tccaaaacgt ctgccagcca gtacgcgctg tttgtggaag atgaatggcg gatcttcgag
     6721 ccgctggcgc tgacgaccgg cgtgcgtatg gacgatcacg aaacctacgg tgaacactgg
     6781 agtccgcgtg cctacctggt ttataacgcc accgacaccg taacggtgaa agggggctgg
     6841 gcgacggcat ttaaagcacc ttctctgttg caacttagcc ctgactggac gagcaattcc
     6901 tgccgtggcg catgtaagat tgtgggtagc ccggatctga aaccagaaac cagcgaaagt
     6961 tgggagctgg ggctttacta catgggtgaa gaaggctggc tggaaggggt tgaatccagc
     7021 gttaccgttt tccgtaacga tgtgaaagat cgtatcagca tcagccgtac gtctgacgtc
     7081 aacgctgcac cgggctacca aaactttgtt ggttttgaga cgggcgctaa cggacggcgc
     7141 ataccggtat ttagctacta caacgttaac aaagctcgta ttcagggcgt ggaaaccgaa
     7201 ctgaaaattc cgttcaacga tgaatggaaa ctgtcgatca actacaccta caacgatggt
     7261 cgtgatgtca gcaacggcga aaacaaaccg ctatccgatc tgccgttcca tactgctaac
     7321 ggtacgctgg actggaaacc gctggcgctg gaagactggt cattctatgt ttctgggcac
     7381 tataccgggc agaaacgcgc cgacagcgcg acggctaaaa caccgggcgg ttataccatc
     7441 tggaataccg gcgcggcctg gcaggtgact aaagacgtca aactgcgcgc aggcgtgctg
     7501 aaccttggcg acaaggatct cagtcgtgac gactacagct ataacgaaga cggacgtcgt
     7561 tactttatgg cagtggatta tcgcttctga tgagaagatg cccggcgaac cgggcggact
     7621 ttcacttcag taaatactgc gcatggaagc gcaggtgatc ctctataaaa gaggcgatga
     7681 agtagtaact gtgatcatat cccggctgaa tacgcagcgt catcggccac gctttctggc
     7741 gcgcggcttc tgccagtacc gcaggttgca actggtcggc aagaaactga tcattatcgc
     7801 cctgatcgat aagcgtcggg atcgcatcct gcgcgttact ggcatacatc agtgcgcaac
     7861 tgtcccattc cagccatgca tttttgtcct cacctaaata gctgctaaac gctttgattc
     7921 cccacgggac gctgcacgga ttcacaattg gcgcaaaggc cgaaacgctg gtgtatttac
     7981 ccggattttt cagcgccata atcagcgcac cgtgaccacc cattgagtga ccgctaatgg
     8041 cgcagcggtc gctgacatta aattgcgact gaaccagcgc cggtaattca tcgcgcagat
     8101 aatcatacat ccggtaatgc gtcgcccacg gcggttgcgt ggcattaaga taaaagcctg
     8161 cgccctggcc taaatcgtag ccatcgtcgt tggcaacctt ttcgccgcgc gggctggtgt
     8221 ctggcatcac cagtacaatc cccagttccg ccgctacccg ctgggcaccc gccttggtgg
     8281 tgaagttctc gtcattgcag gttaatccgg aaagccagta cagcactggt ggcggagtgt
     8341 gatcacgagg tggagggaga aagatactga acgtcatcgg gcagtttaag gtactggagt
     8401 cgtgtcgcca gcgttgctgc cagccttcaa aacagcggtg ctcttcgagc atttccatgc
     8461 gtggctcctt gttgtgttgt ttgcaatttc ttcatcatac cgtttattca atgtgctgtg
     8521 agtaactttc acttccgtat ttgcataacg atgttttaac atctgctgat gaaaggcagc
     8581 ggcaattaca ataattatcg ctgtgaatac tggattatgt gcgccgcctc acgcacaata
     8641 atcaggctgt aaatcagctt aataactttg cccccacgca gggcggaggc gtcacacctg
     8701 caggagaaat cataaatgcc atcactcagt aaagaagcgg ccctggttca tgaagcgtta
     8761 gttgcgcgag gactggaaac accgctgcgc ccgcccgtgc atgaaatgga taacgaaacg
     8821 cgcaaaagcc ttattgctgg tcatatgacc gaaatcatgc agctgctgaa tctcgacctg
     8881 gctgatgaca gtttgatgga aacgccgcat cgcatcgcta aaatgtatgt cgatgaaatt
     8941 ttctccggtc tggattacgc caacttcccg aaaatcaccc tcattgaaaa caaaatgaag
     9001 gtcgatgaaa tggtcaccgt gcgcgatatc actctgacca gtacctgtga acaccatttt
     9061 gttaccatcg atggcaaagc gacggtggct tatatcccga aagattcggt gatcggtctg
     9121 tcaaaaatta accgtatcgt gcagttcttt gcccagcgtc cgcaggtgca ggaacgtctg
     9181 acgcagcaaa ttcttattgc gctacaaacg ctgctgggca ccaataacgt ggctgtctcg
     9241 atcgacgcgg tgcattactg cgtgaaggcg cgtggcatcc gcgatgcaac cagtgccacg
     9301 acaacgacct ctcttggtgg attgttcaaa tccagtcaga atacgcgcca cgagtttctg
     9361 cgcgctgtgc gtcatcacaa ctgattaaaa ggcaggaacc atggagcgca acgtcacgct
     9421 cgattttgtt cgcggcgtcg ccattctggg gatcctgcta ttaaacatca gcgcctttgg
     9481 gctaccaaag gcggcttatc ttaatcccgc ctggtacggc gctattacgc cgcaggatgc
     9541 atggacctgg gcatttcttg atctcgtcgg ccaggtgaaa ttcctcacgc tttttgcgct
     9601 gctgtttggt gcgggcctgc aaatgttgct gccccgtggc agacgctgga tccagtcgcg
     9661 gttaacgctg ttagtcttgt tgggctttat tcacggttta ctgttctggg acggcgatat
     9721 tctgctggct tacgggctgg tgggcttaat ctgctggcgg ctggtgcgcg atgcgccatc
     9781 ggtaaaaagc ctgtttaata caggcgtcat gctttatctg gtggggcttg gcgttttgct
     9841 gttattgggg ttgatttccg atagccagac cagccgcgcc tggacgccgg atgcatcggc
     9901 tattttgtat gaaaaatact ggaagcttca cggcggcgtt gatgcgatca gtaatcgtgc
     9961 cgatggtgtt ggcaacagtt tactggcact gggcgcacag tatggctggc aactggctgg
    10021 gatgatgctc attggtgccg cattgatgcg cagtggctgg ctgaaagggc agttcagctt
    10081 acgtcactat cgtcgtactg gttttgtgct ggtggcgatt ggggtgatca ttaaccttcc
    10141 tgccatcgcc ctgcaatggc ggctggactg ggcatatcgc tggtgcgcct tcttacttca
    10201 gatgccacgg gaactgagtg cgccgtttca ggcgataggc tatgcgtcgc tgttttatgg
    10261 tttctggccg caattgagcc gctttaagct ggtgcttgcg atcgcctgcg tcggacggat
    10321 ggcgctgacc aactatctat tgcaaacgct gatttgtacc acgctttttt accacctcgg
    10381 tttgtttatg cattttgacc gcctggagct gctggcgttt gttattccgg tatggctggc
    10441 gaatatcctc ttctctgtta tctggctgcg tttcttccgc caggggccgg tggaatggct
    10501 ctggcgtcag ttaactttgc gtgctgccgg accggcaata tctaaaacat caagataacg
    10561 atctggatca cattcgttaa caaaacggct gtaaccgttt ccattgctgt gactcgattc
    10621 acgaagtcct gtattcagtg ctgacaaaat agccgccagc aagcagtcat ttactgcaat
    10681 ctcataacag gtagtgaata tgatcaccat tcgtgatgta gcgcgtcagg ctggcgtctc
    10741 tgtggcaacg gtttcccggg tgctcaataa cagcacgctg gtcagtgccg acacgcgtga
    10801 agcagtaatg aaagccgtga gtgagctgga ttatcggcca aacgccaatg cccaggcgct
    10861 ggcaactcag gttagcgaca ccattggcgt ggtggtgatg gacgtttctg atgcgttttt
    10921 cggcgcgctg gtaaaagcgg tggatctagt cgctcagcag catcagaaat acgtgctaat
    10981 cggcaatagc tatcatgaag cggaaaaaga gcgtcacgcc attgaggtgt taattcgcca
    11041 gcgttgtaat gcgttgattg ttcactcaaa agcattgagt gacgatgaac tggcgcaatt
    11101 tatggataac attcccggta tggtgttaat caaccgcgtt gtgccggggt acgcccatcg
    11161 ttgcgtttgc ctggataatc tcagcggtgc ccgaatggcg acgcgcatgt tgctgaataa
    11221 cggtcatcaa cgtattggtt atctttcttc cagtcacggc attgaagatg acgccatgcg
    11281 taaagcaggc tggatgagtg cgttgaaaga gcaggatatt attccgccgg aaagctggat
    11341 tggcactggt acgccggaca tgccgggcgg tgaggcggcg atggttgaac tgctggggcg
    11401 caatctacaa cttaccgctg tatttgctta taacgacaat atggccgctg gcgcactgac
    11461 agcattaaaa gataatggca ttgcgattcc gttacatctc tcaatcatcg gtttcgatga
    11521 tattcccatc gcccgttaca ccgacccgca attaacgacc gtgcgttatc ccattgcttc
    11581 aatggctaaa ttagccaccg aactggcctt gcagggggca gcaggcaata ttgatcctcg
    11641 tgccagccac tgttttatgc cgacgttagt gcgtcgccat tctgtcgcaa cgcgccagaa
    11701 tgcggcggcg atcactaact caacaaatca ggcgatgtaa ccgctttcaa tctgtgagtg
    11761 atttcacagt atcttaacaa tgtgatggct atgattgcac cgttttaacg ttgtaacccg
    11821 tatgtaacag tgaataatca ctttcaccga ggtaatagcg tcataacaac aattaaagcc
    11881 gttttctgga gcgttaccgg gcatggaaga acgaatttta aaaagtgagc ttcggcgttc
    11941 agtaacactt cattaactct actgccccgc cgagcattta tctcaagcac tatcctgcat
    12001 aagaaaaacc ggagatacca tgaataagaa ggtgttaacc ctgtctgctg tgatggccag
    12061 catgttattc ggtgccgctg cacacgctgc tgatactcgc attggtgtaa caatctataa
    12121 gtacgacgat aactttatgt ctgtagtgcg caaggctatt gagcaagatg cgaaagccgc
    12181 gccagatgtt cagctgctga tgaatgattc tcagaatgac cagtccaagc agaacgatca
    12241 gatcgacgta ttgctggcga aaggggtgaa ggcactggca atcaacctgg ttgacccggc
    12301 agctgcgggt acggtgattg agaaagcgcg tgggcaaaac gtgccggtgg ttttcttcaa
    12361 caaagaaccg tctcgtaagg cgctggatag ctacgacaaa gcctactacg ttggcactga
    12421 ttccaaagag tccggcatta ttcagggcga tttgattgct aaacactggg cggcgaatca
    12481 gggttgggat ctgaacaaag acggtcagat tcaattcgta ttgctgaaag gtgaaccggg
    12541 ccatccggat gcagaagcac gtaccactta cgtgattaaa gagctgaacg acaaaggcat
    12601 taaaactgaa cagttacagt tagataccgc tatgtgggat accgctcagg cgaaagataa
    12661 gatggacgcc tggctgtctg gcccgaacgc caacaaaatc gaagtggtta tcgccaacaa
    12721 cgatgcgatg gcaatgggcg cggtagaagc actgaaagca cacaacaagt ccagcattcc
    12781 ggtgtttggc gtcgatgcgc tgccagaagc gctggcgctg gtgaaatccg gtgcactggc
    12841 gggcacagta ctgaacgatg ctaacaacca ggcgaaagcg acctttgatc tggcgaaaaa
    12901 cctggccgat ggcaaaggtg cggctgatgg caccaactgg aaaatcgaca acaaagtggt
    12961 ccgcgtacct tatgttggcg tagataaaga caacctggct gaattcagca agaaataaga
    13021 ctgattgggc gcagtcgttt actgcgccct tattgtatgg ccaacaaggt aaaattatat
    13081 ggtcagctca acgactccgt cttccgggga atacttgttg gaaatgagcg gtatcaacaa
    13141 gtcttttcct ggtgttaagg cacttgataa cgttaattta aaagtccggc cacattctat
    13201 ccatgcatta atgggggaaa acggcgcagg aaaatcaaca ttattaaaat gcctgtttgg
    13261 tatttatcaa aaagactccg gcaccatttt attccagggt aaagagatcg atttccattc
    13321 tgccaaagaa gcactggaaa atggtatttc gatggtacac caggagttaa acctggtatt
    13381 acaacgttcg gtgatggata acatgtggct ggggcgatat cccaccaaag gcatgtttgt
    13441 cgatcaggac aaaatgtacc gcgaaaccaa agcgattttt gatgaactgg atattgatat
    13501 cgatccgcgt gcgcgcgtcg gcacattatc cgtttcgcaa atgcagatga tcgaaatcgc
    13561 caaagcgttt tcctataacg cgaaaattgt gattatggat gaaccgactt cttcgttaac
    13621 cgaaaaagag gtcaatcatc tgttcactat tattcgtaaa ttaaaagagc gcggctgcgg
    13681 tattgtttat atctcgcata aaatggaaga aatcttccag ttatgtgatg aagttaccgt
    13741 attgcgcgac ggtcagtgga tcgccaccga accgctggca ggactgacga tggacaagat
    13801 catcgccatg atggttgggc gttctcttaa tcagcgtttt cctgacaaag aaaacaagcc
    13861 gggcgaagtc atcctcgagg tgcgtaacct gacgtcactg cgccagccgt cgattcgcga
    13921 tgtctcgttt gatctgcata aaggggagat cctcggtatt gccgggctgg tgggggcgaa
    13981 acgtaccgat attgttgaga cgttatttgg tattcgcgag aaatcggctg gcaccataac
    14041 gttgcacggc aaacagatca ataaccataa tgccaacgaa gccataaacc acggatttgc
    14101 actggtaact gaggagcgcc gctcaacggg aatttatgcc tatctggata ttggttttaa
    14161 ctcgttaatt tccaatattc gcaactacaa aaataaagtt ggtttactgg ataactcgcg
    14221 gatgaaaagc gatacccagt gggtgattga ttc
//
LOCUS       DACAOP010000109        13929 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.109, whole genome shotgun sequence.
ACCESSION   DACAOP010000109 DACAOP010000000
VERSION     DACAOP010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13929
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.109"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..377)
                     /locus_tag="IT892_003735"
     CDS             complement(<1..377)
                     /locus_tag="IT892_003735"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312155.1"
                     /note="an AccC homodimer forms the biotin carboxylase
                     subunit of the acetyl CoA carboxylase, an enzyme that
                     catalyzes the formation of malonyl-CoA, which in turn
                     controls the rate of fatty acid metabolism; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAP3136895.1"
                     /translation="MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLL
                     ADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIF
                     IGPKAETIRLMGDKVSAIAAMKKA"
     gene            complement(388..858)
                     /gene="accB"
                     /locus_tag="IT892_003736"
                     /gene_synonym="fabE"
     CDS             complement(388..858)
                     /gene="accB"
                     /locus_tag="IT892_003736"
                     /gene_synonym="fabE"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAP3136896.1"
                     /translation="MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVM
                     QQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAF
                     IEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE"
     gene            complement(1836..2810)
                     /locus_tag="IT892_003737"
     CDS             complement(1836..2810)
                     /locus_tag="IT892_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP3136897.1"
                     /translation="MQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDA
                     LAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAGQEVLLTGWGVGENHWGGLAEQA
                     RVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVG
                     STAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVLPRDEFAESRPLEKQVWAGAIDT
                     VGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRA
                     QAWQRLVADLPESFYTQAAKEISLSEAPNFAEAIINNQIQGRTLVKVN"
     gene            2962..4902
                     /gene="csrD"
                     /locus_tag="IT892_003738"
     CDS             2962..4902
                     /gene="csrD"
                     /locus_tag="IT892_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase E specificity factor CsrD"
                     /protein_id="HAP3136898.1"
                     /translation="MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQA
                     VATAIDTHLVSNDFSVLRPQITELMMSADIVRVDLLHGDKQVYTLARNGSYRPVGSSD
                     LFRELSVPLIKHPGMSLRLVYQDPMGNYFHSLMTTAPLTGAIGFIIVMLFLAVRWLQR
                     QLAGQELLETRATRILNGERGSNVLGTIYEWPPRTSSALDTLLREIQNAREQHSRLDT
                     LIRSYAAQDVKTGLNNRLFFDNQLATLLEDQEKVGTHGIVMMIRLPDFNMLSDTWGHS
                     QVEEQFFTLTNLLSTFMMRYPGALLARYHRSDFAALLPHRTLKEAESIAGQLIKAVDT
                     LPNNKMLDRDDMIHIGICAWRSGQDTEQVMEHAESATRNAGLQGGNSWAIYDDSLPEK
                     GRGNVRWRTLIEQMLSRGGPRLYQKPAVTREGQVHHRELMCRIFDGNEEVSSAEYMPM
                     VLQFGLSEEYDRLQISRLIPLLRYWPEENLAIQVTVESLIRPRFQRWLRDTLMQCEKS
                     QRKRIIIELAEADVGQHISRLQPVIRLVNALGVRVAVNQAGLTLVSTSWIKELNVELL
                     KLHPGLVRNIEKRTENQLLVQSLVEACSGTSTQVYATGVRSRSEWQTLIQRGVTGGQG
                     DFFASSQPLDTNVKKYSQRYSV"
     gene            5207..6250
                     /locus_tag="IT892_003739"
     CDS             5207..6250
                     /locus_tag="IT892_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HAP3136899.1"
                     /translation="MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQD
                     RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS
                     FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
                     SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERI
                     KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE
                     QCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALE
                     MIDMHGGDLFSEE"
     gene            6316..7419
                     /gene="mreC"
                     /locus_tag="IT892_003740"
     CDS             6316..7419
                     /gene="mreC"
                     /locus_tag="IT892_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAP3136900.1"
                     /translation="MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDT
                     AVSPFYFVSNAPRELLDGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENA
                     RLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
                     VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGD
                     VLVTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNG
                     ANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQPTPQQPATGNAATA
                     PAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ"
     gene            7419..7907
                     /gene="mreD"
                     /locus_tag="IT892_003741"
     CDS             7419..7907
                     /gene="mreD"
                     /locus_tag="IT892_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAP3136901.1"
                     /translation="MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILL
                     YWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLAMSIIAYLVALKYQLFRNLALWQ
                     QALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
                     VQ"
     gene            7916..8509
                     /gene="yhdE"
                     /locus_tag="IT892_003742"
     CDS             7916..8509
                     /gene="yhdE"
                     /locus_tag="IT892_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase YhdE"
                     /protein_id="HAP3136902.1"
                     /translation="MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQY
                     VVRLAREKARAGVAQTAKDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQ
                     VMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASDEPLDKAGAYGIQGLGGCFV
                     RKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG"
     gene            8499..9968
                     /gene="rng"
                     /locus_tag="IT892_003743"
     CDS             8499..9968
                     /gene="rng"
                     /locus_tag="IT892_003743"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HAP3136903.1"
                     /translation="MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKG
                     RVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECVAGEEQKQFTVRDISELVRQGQD
                     LMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
                     YCDEQGGFIIRTAAEGVGEAELASDAAYLKRVWTKVMERKKRPQTRYQLYGELALAQR
                     VLRDFADAELDRIRVDSRLTYEALLEFTSEYIPEMTSKLEHYTGRQPIFDLFDVENEI
                     QRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTIFNTNIEATQAIARQ
                     LRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSVNGFSALGLVEMTRKR
                     TRESIEHVLCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAE
                     ALKGEESHSLAEVEIFVGKQVKVQIEPLYNQEQFDVVMM"
     gene            10036..13836
                     /locus_tag="IT892_003744"
     CDS             10036..13836
                     /locus_tag="IT892_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA2 domain-containing protein"
                     /protein_id="HAP3136904.1"
                     /translation="MRRLPGILLLTGAALVVIAALLVSGLRIALPHLDAWRPEILNKI
                     ESATGMPVEASQLSASWQNFGPTLEAHDIRAELKDGGEFSVKRVTLALDVWQSLLHMR
                     WQFRDLTFWQLRFRTNTPITSGGSDDSLEASHISDLFLRQFDHFDLRDSEVSFLTPSG
                     QRAELAIPQLTWLNDPRRHRAEGLVSLSSLTGQHGVMQVRMDLRDDEGLLSNGRVWLQ
                     ADDIDLKPWLGKWMQDNIALETAQFSLEGWMTIDKGDVTGGDVWLKQGGASWLGEKQT
                     HTLSVDNLTAHITRENPGWQFSIPDTRITMDGKPWPSGALTLAWIPEQDVGGKDNKRS
                     DELRIRASNLELAGLEGIRPLAAKLSPALGDVWRSTQPSGKINTLALDIPLQAADKTR
                     FQASWSDLAWKQWKLLPGAEHFSGTLSGSVENGLLTASMKQAKMPYETVFRAPLEIAD
                     GQATISWLNNNKGFQLDGRNIDVKAKAVHARGGFRYLQPANDEPWLGILAGISTDDGS
                     QAWRYFPENLMGKDLVDYLSGAIQGGEADNATLVYGGNPQLFPYKHNEGQFEVLVPLR
                     NAKFAFQPDWPALTNLDIELDFINDGLWMKTDGVNLGGVRASNLTAVIPDYSKEKLLI
                     DADIKGPGKAVGPYFDETPLKDSLGATLQELQLDGDVNARLHLDIPLNGELVTAKGEV
                     TLRNNSLFIKPLDSTLKNLSGKFSFINSDLQSEPLTASWFNQPLNVDFSTKEGAKAYQ
                     VAVNLNGNWQPAKTGVLPEAVNEALSGSVAWDGKVGIDLPYHAGATYNIELNGDLKNV
                     SSHLPSPLAKPAGEPLAVNVKVDGNLNSFELTGQAGADNHFNSRWLLGQKLTLDRAIW
                     AADSKTLPPLPEQSGVELNMPPMNGAEWLALFQKGAAESVGGAASFPQHITLRTPMLS
                     LGNQQWNNLSIVSQPTANGTLVEAQGREINATLAMRNNAPWLANIKYLYYNPSVAKTR
                     GDSTPSSPFPTTERINFRGWPDAQIRCTECWFWGQKFGRIDSDITISGDTLTLTNGLI
                     DTGFSRLTADGEWVNNPGNERTSLKGKLRGQKIDAAAEFFGVTTPIRQSSFNVDYDLH
                     WRKAPWQPDEATLNGIIHTQLGKGEITEINTGHAGQLLRLLSVDALMRKLRFDFRDTF
                     GEGFYFDSIRSTAWIKDGVMHTDDTLVDGLEADIAMKGSVNLVRRDLNMEAVVAPEIS
                     ATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYHISGPLDDPQINEVLRQPRK
                     EKAQ"
BASE COUNT         3299 a         3450 c         3830 g         3350 t
ORIGIN      
        1 gcttttttca tcgccgcgat tgcggatact ttgtcgccca tcaggcgaat ggtttctgct
       61 ttcgggccaa tgaagataaa gccggagcgt tcaacctgct cggcaaagtt ggcgttctcg
      121 gagaggaagc cgtaacccgg atggattgct actgcgccgg tgatttcagc ggcgctgatg
      181 attgccggga tgttcagata actttttact gacggagcag ggccaataca gaccgtttca
      241 tctgccagta atacgtgttt tagatcgcga tccgcgctgg agtgcacagc gacagtcttg
      301 atgcccagtt ctttacaggc acgaagaata cgcaatgcaa tctcgccgcg gttggcaata
      361 acaattttat ccagcatgtt cgcctcgtta ctcgatgacg accagcggct cgtcaaattc
      421 taccggttgt ccactttcga ccagaattgc tttcacggta ccggatttgt ccgcttcgat
      481 ctggttcatc attttcatgg cttcaacgat gcacagggta tcgcccacgt tgactttctg
      541 acccacttcg atgaacgctt ttgcgtccgg gcttggggtg cggtagaaag taccaaccat
      601 cggggaacgt acgatgtgac cactgatttc cgctgctgct ggcgcttcca tggaaggaac
      661 ggtcgccgga gcggctgcgt tagattgagc tggctgctgc atcattggtg cagcgtaagc
      721 ttgttgcatc acagggaaac ttgcggcagg agctgcacgg ctaatgcgta ctgactcttc
      781 gccttcagaa atttccagtt cggagatgcc tgattcttca accagctcga tcagtttttt
      841 aatcttacga atatccatga gtgggttccg tactctttgt ttagtgtgat tgtgacaggc
      901 gtttcaccgc cgtctgtaaa gcgtatgccc cgacagctgt atgcatagcg ataaattcca
      961 gcaggccggg acgccggtct attttgcccc agagtgtcaa tgttagactt gacggacatt
     1021 gtgcagcgat ctgctgctat cctccggcaa aaaacaaaat ataccttcgt tgcgccaatg
     1081 tcaccttttc cgcagcgcaa aaactgcgtc agggaggacg aggtcgcaca ttataacgat
     1141 ttcgtagcaa ttggcagcta aatactggtc ttatcaggga agataatcaa cagctaacat
     1201 gtaaataacc ttcaacaccg tgtaatttgc aacaagccgc acaattcacg aaattagcgc
     1261 catcatcgac ggaacttctt ataacgtaag gtgaaaagct gaaaagccag ccctgcgaag
     1321 atgaggggct gcaatgagat aatcttcaca gaccacaaat aatgtaggga tgccaggatc
     1381 gcgacaagat agacgacatt acgcagcggt tgctggggat tacccaattt tcactgcatc
     1441 gtctggatag atgtgaatgc taaagcacgc aaaattaacc gattgacaat gctcagcatt
     1501 aaataggttc gagtgattaa tttgtagtca aacaaaatca gattattcac cccatggtac
     1561 cagaaataag taaggggcta agcgtagcgt cgcccaggca aagcaccata aacctaacag
     1621 gcgacggagg cgtatcaata atagctgttt agtggagtat caatgcgcat caatttgtgg
     1681 tcagtcgaaa tcatgacttt ccagtttgga tgatgttgta taacttcctg accaaggtgt
     1741 tcgacgaaag ctgtccggct aaccgctttt cccgttaacc gattgaataa tgatttcaaa
     1801 atgagttccc tctcttatta ttccctgcta aatggttagt taaccttcac cagcgtgcga
     1861 ccctggatct ggttattaat gatggcctcg gcaaagttcg gtgcctctga cagagatatc
     1921 tcttttgccg cctgggtata gaatgattcc ggtaaatcgg cgaccagtcg ctgccaggct
     1981 tgtgcgcggc gttctggtgg cgtcattact gaatccaccc cttgcaaacg gacattacgc
     2041 agaataaatg gcatgaccgt ggttggcaga gtaaaaccac ccgccagacc acaggccgcc
     2101 acgcagccgc cgtaattcat ttgcgccagc acttttgcca gcactttgtc gccaacggtg
     2161 tcaattgccc cagcccagac ttgtttttcc agaggacggg attcggcaaa ctcatcacga
     2221 gggagaacac ggctagcacc taaacttttc agatattcat gggtactttc gcgaccggaa
     2281 acggcaacga cctgataacc caacttatgc agcagcgcca cggcggtact gccgacgcca
     2341 ccactggcac ccgtcacgac aatctccccg tcctgcgggc gaacaccggc atcttccagc
     2401 gccatcacac acagcatggc ggtaaaaccg gcagtaccga taatcattgc tttacgcgcg
     2461 tccagccctt gcggcatggc aaccagccag tcacctttca ctcgcgcctg ctccgccagc
     2521 ccaccccagt ggttttcacc aacgccccag ccagtgagta acacctcctg accggcatga
     2581 aaacgcggat cttcgctggt gcgtacagtt ccggcaaaat cgatcccagg aatcatcgga
     2641 aaattacgga tgatttttcc cttaccggta atcgccagcg catctttata gttcaggctc
     2701 gaccagtgaa catcgaccgt gacatcgccc tccggcaggc gactttcgtc cagagtctgt
     2761 actgatgcga gagttttgcc gtcctgctgt tctaaaagta acgcctgcat aagtggtcct
     2821 catgtgcatg atggattgga aaataatttc tgaagactat actcgctaat ggaaaagcaa
     2881 agccgatgaa gcgcaataaa ttgcgagata aatctgattt gctagtatgc ccgcttcctc
     2941 actatcggag ttaacacaag gatgagatta acgacgaaat tttcggcctt tgttacgctg
     3001 ctcaccgggt taacaatttt tgtgactttg ctgggctgtt cgctaagttt ctacaacgcc
     3061 attcagtata agtttagtca tcgcgttcag gcggtggcga cggcgattga tacccacctt
     3121 gtgtcgaatg acttcagcgt attaaggcca caaattaccg aattaatgat gtcggcagat
     3181 atcgttcgtg tagacctgct ccatggtgat aaacaggttt ataccctggc cagaaatggt
     3241 agttatcgtc cagttggctc cagcgatctg tttcgcgaac tgagcgttcc gttgataaag
     3301 catccgggga tgtcgttgcg tctggtttat caggatccga tgggcaacta tttccattcg
     3361 ttgatgacca ccgcgccgct cacgggggcg attggcttta tcattgttat gctcttcctg
     3421 gcggtacgct ggttacaacg gcaacttgcc gggcaagaat tgctggaaac ccgggctact
     3481 cgtatcttaa acggtgagcg tggctctaat gtgttgggaa ccatctatga atggccgccc
     3541 agaaccagca gtgcgctgga tacgctgctt cgtgaaattc agaacgcacg cgaacaacac
     3601 agccgtcttg atacgctgat ccgctcttat gccgcccagg acgtgaaaac cggcctcaat
     3661 aaccgactct ttttcgataa tcagttagca acgttactgg aagatcagga gaaagtaggt
     3721 acccacggga tcgtgatgat gattcgtctg ccggatttca atatgttgag cgatacctgg
     3781 gggcacagcc aggttgaaga acagttcttc actctgacga atctgctgtc gacatttatg
     3841 atgcgctacc ctggcgcact gctggcgcgt taccaccgca gtgattttgc tgcgctgtta
     3901 ccgcaccgga cgttaaaaga ggcagagagc atcgccggtc agttaatcaa agccgttgat
     3961 accttgccga acaataaaat gctcgatcgc gacgatatga tccacattgg tatctgcgcc
     4021 tggcgtagtg gtcaggatac cgagcaggta atggaacatg cagagtctgc cacgcgtaat
     4081 gcgggattgc agggcggcaa tagctgggct atttacgatg actcgttgcc tgaaaaagga
     4141 cgcggtaatg ttcgctggcg tacgcttatc gagcaaatgc tcagtcgcgg cggcccgcgc
     4201 ctttatcaaa aaccggcggt tactcgcgaa ggtcaggttc atcatcgcga actcatgtgc
     4261 cgcatcttcg atggtaatga agaggttagc tcggcggagt atatgccgat ggtcttgcag
     4321 tttggcttat cggaagagta tgaccgtctg caaatcagcc gtcttattcc actattgcgt
     4381 tactggccag aggaaaatct ggcgattcag gttaccgttg agtcgctgat tcgcccgcgt
     4441 tttcagcgtt ggctgcgcga tacgttaatg caatgtgaaa aatcacaacg aaaacgcata
     4501 attattgaac ttgcagaggc cgatgtaggt caacatatca gtcgtttaca acctgttatt
     4561 cgtttagtga atgctttagg ggtacgggta gccgtcaacc aggctggttt gacgctggta
     4621 agtaccagtt ggatcaaaga acttaatgtt gagttactca agctccatcc ggggctggtc
     4681 agaaacattg agaagcgaac ggagaaccag ctgctggttc aaagcctggt ggaagcctgc
     4741 tccgggacca gcacccaggt ttacgccacc ggcgtgcgtt cgcgaagcga gtggcagacc
     4801 ctgattcagc gcggtgttac aggcgggcaa ggggattttt tcgcgtcctc acagccactt
     4861 gatactaacg tgaaaaaata ttcacaaaga tactcggttt aacctgccgt ttaatccgtt
     4921 ttcacgtaga ataacgcgcg ctgcgtctca tgggagtgtg cttgtctgct cgccagattg
     4981 ttgcagcaca tatgcagatg aatgacctta cgcggttgca aacaggcgag gaatgctgct
     5041 gatgcattaa gcctttctgg actcaggcag agatttgtaa caaaggaaac gaactgcact
     5101 aattttcacc gtagcagatg atttttgcgc cttgtcgctg ctgcgtgtgg ttggtaaagt
     5161 aagcggattt tcttttccgc cccagctttc aggattatcc cttagtatgt tgaaaaaatt
     5221 tcgtggcatg ttttccaatg acttgtccat tgacctgggt actgcgaata ccctcattta
     5281 tgtaaaagga caaggcatcg tattgaatga gccttccgtg gtggccattc gtcaggatcg
     5341 tgccggttca ccgaaaagcg tagctgcagt aggtcatgac gcgaagcaga tgctgggccg
     5401 tacgccgggc aatattgctg ccattcgccc aatgaaagac ggcgttatcg ccgacttctt
     5461 cgtgactgaa aaaatgctcc agcacttcat caaacaagtg cacagcaaca gctttatgcg
     5521 tccaagcccg cgcgttctgg tttgtgtgcc ggttggcgcg acccaggttg aacgccgcgc
     5581 aattcgtgaa tccgcgcagg gcgctggtgc ccgtgaagtc ttcctgattg aagaaccgat
     5641 ggctgccgca attggtgctg gcctgccggt ttctgaagcg accggttcta tggtggttga
     5701 tatcggtggt ggtaccactg aagttgctgt tatctccttg aacggtgtgg tttactcctc
     5761 ttctgtgcgc attggtggtg accgtttcga cgaagctatc atcaactatg tgcgtcgtaa
     5821 ttacggttct ctgatcggtg aagccaccgc agaacgtatc aagcacgaaa tcggttcggc
     5881 ttatccgggc gatgaagtcc gtgaaatcga agttcgtggc cgtaacctgg cagaaggtgt
     5941 tccacgcggt tttaccctga actccaatga aatcctcgaa gcactgcagg aaccgctgac
     6001 cggtattgtg agcgcggtaa tggttgcact ggaacagtgc ccgccggaac tggcttccga
     6061 catctccgag cgcggcatgg tgctcaccgg tggtggcgca ctgctgcgta accttgaccg
     6121 tttgttaatg gaagaaaccg gcattccagt cgttgttgct gaagacccgc tgacctgtgt
     6181 ggcgcgcggt ggcggcaaag cgctggaaat gatcgacatg cacggcggcg acctgttcag
     6241 cgaagagtaa tcggatgcag gcaggggaag tgtctgttta ccctgcctgg tctgatacga
     6301 gaatacgcat aacttatgaa gccaattttt agccgtggcc cgtcgctaca gattcgcctt
     6361 attctggcgg tgctggtggc gctcggcatt attattgccg acagccgcct ggggacgttc
     6421 agtcaaatcc gtacttatat ggataccgcc gtcagtcctt tctactttgt ttccaatgct
     6481 cctcgtgaat tgctggatgg cgtatcgcag acgctggcct cgcgtgacca attagaactt
     6541 gaaaaccggg cgttacgtca ggaactgttg ctgaaaaaca gtgaactgct gatgcttgga
     6601 caatacaaac aggagaacgc gcgtctgcgc gagctgctgg gttccccgct gcgtcaggat
     6661 gagcagaaaa tggtgactca ggttatctcc acggttaacg atccttatag cgatcaagtt
     6721 gttatcgata aaggtagcgt taatggcgtt tatgaaggcc agccggtcat cagcgacaaa
     6781 ggtgttgttg gtcaggtggt ggccgtcgct aaactgacca gtcgcgtgct gctgatttgt
     6841 gatgcgaccc acgcgctgcc aatccaggtg ctgcgcaacg atatccgcgt aattgcagcc
     6901 ggtaacggtt gtacggatga tttgcagctt gagcatctgc cggcgaatac ggatattcgt
     6961 gttggtgatg tgctggtgac ttccggtctg ggcggtcgtt tcccggaagg ctatccggtc
     7021 gcggttgtct cttccgtaaa actcgatacc cagcgcgctt atactgtgat tcaggcgcgt
     7081 ccgactgcag ggctgcaacg tttgcgttat ctgctgctgc tgtggggggc agatcgtaac
     7141 ggcgctaacc cgatgacgcc ggaagaggtg catcgtgttg ctaatgaacg tctgatgcag
     7201 atgatgccgc aggtattgcc ttcgccagac gcgatggggc caaagttacc tgaaccggca
     7261 acggggatcg ctcagccgac tccgcagcaa ccggcgacag gaaatgcagc tactgcgcct
     7321 gctgcgccga cacagcctgc tgctaatcgc tctccacaaa gggctacgcc gccgcaaagt
     7381 ggtgctcaac cgcctgcgcg tgcgccggga gggcaatagt ggcgagctat cgtagccagg
     7441 gacgctgggt aatctggctc tctttcctca ttgcgctgtt gctgcaaatc atgccctggc
     7501 cggataacct gattgttttc cggccaaact gggtgttact catcttgttg tattggatcc
     7561 tggccttgcc tcatcgcgta aatgtgggca caggttttgt gatgggtgcc atactggatc
     7621 tgatcagcgg ctcgacgctt ggcgtacgcg tattggcgat gagcatcatt gcttacctgg
     7681 tggcgctgaa ataccagctt ttccgcaacc tcgcattatg gcagcaggcg ctggtcgtca
     7741 tgttgctttc gctggtggtg gatattattg ttttctgggc agagttttta gtgattaacg
     7801 tctctttcag accggaagtg ttctggagta gtgtagtcaa tggggtgctc tggccgtgga
     7861 ttttcttgct gatgcgcaaa gtccgtcagc agtttgcagt gcaataaagg tttctatgac
     7921 ttctctgtat ttagcttccg gttctccgcg tcgtcaggag ttacttgcgc aacttggcgt
     7981 gacctttgaa cgtattgtta cgggcattga ggagcagcgt cagccgcagg agagcgcgca
     8041 gcagtatgtt gtgcgtctgg cgcgcgagaa agcacgggca ggtgtcgcgc aaacggcgaa
     8101 ggatctcccg gtgctgggtg cggatactat cgttatcctg aacggagaag tgctggagaa
     8161 accgcgcgac gcagagcatg cggcgcagat gttgcgcaaa ttatcgggtc agacccatca
     8221 ggtgatgaca gcagtggcgt tggccgacag ccagcacatt ctcgattgcc tggtggtcac
     8281 cgatgtgact ttcagaacgt taacagacga agacatcgcg ggctatgtcg ccagcgatga
     8341 accgttagat aaagcaggtg catacggtat tcaggggctg ggtggctgtt ttgtcaggaa
     8401 gataaatggc agctatcacg ccgtagtcgg cttaccgctg gttgaaacgt atgaattatt
     8461 aagtaatttt aacgcactgc gtgagaaaag ggataaacat gacggctgaa ttgttagtaa
     8521 acgtaacgcc ttcggaaacg cgagtggcgt atattgatgg cggtattctg caggaaattc
     8581 atattgaacg tgaggcgcga cgcggaatag taggcaatat ctacaagggt cgtgtaagtc
     8641 gtgtacttcc gggtatgcag gcggcttttg tagatattgg gctggataaa gccgcgtttc
     8701 ttcatgcatc cgacatcatg ccgcacaccg aatgtgtggc gggtgaagaa caaaagcaat
     8761 tcacggtgcg cgacatctcg gaactggttc gtcaggggca agatctgatg gtgcaggtgg
     8821 tgaaagatcc gcttggcact aaaggtgcgc gcctgaccac cgatatcacg ctcccttctc
     8881 gctatctggt gtttatgcca ggggcttctc acgttggggt ttcccaacgt attgaaagcg
     8941 aatcagaacg tgaacgcctg aaaaaagtgg tcgcagagta ttgcgacgag cagggcgggt
     9001 ttatcatccg taccgcagcg gaaggggttg gcgaggctga actggcctcc gatgccgctt
     9061 atctgaaacg cgtctggacc aaagttatgg agcgtaaaaa acgcccgcag acccgttatc
     9121 agctgtacgg cgaactggcg ctggcgcagc gtgttctgcg tgatttcgcc gatgccgaac
     9181 tggaccgcat tcgcgttgac tcacgcctga cttacgaagc gttacttgag ttcacctcgg
     9241 agtacattcc cgagatgaca agcaagctgg agcattacac aggacgccag ccgattttcg
     9301 atctctttga tgtcgaaaac gaaatccagc gagcgctgga acgcaaagta gaactgaaat
     9361 ccggtggtta tctcattatc gaccagaccg aagcgatgac caccgtggac atcaataccg
     9421 gagcgtttgt cggtcatcgc aatctggacg acaccatttt caataccaat attgaagcga
     9481 cgcaggctat cgctcgccag ttacggttgc gtaatctggg cgggattatc attattgatt
     9541 tcatcgatat gaataatgaa gatcaccgcc gccgagtgct gcactcgctg gagcaggcgt
     9601 tgagcaaaga ccgggtgaaa accagcgtta atggtttttc ggcgctgggg ctggtggaga
     9661 tgacgcgtaa acgcacccgc gaaagcattg agcacgtact gtgtaacgaa tgcccaacct
     9721 gccacggtcg cggaacggtg aaaaccgtgg aaacggtatg ctatgaaatc atgcgcgaga
     9781 ttgttcgtgt ccaccatgct tacgactccg accgtttcct ggtctatgct tctccggcag
     9841 tagctgaagc cttgaaaggc gaagagtcac actcgctggc ggaagtggaa attttcgttg
     9901 gcaaacaggt taaagtacaa attgaaccgc tctataacca ggagcagttt gacgtcgtaa
     9961 tgatgtaaac agatgctggg ccgccatccg gcaaagggtt tttaagtcac atttttagca
    10021 gacaaggagt gacgggtgag gcgattgccg gggattttac tgcttactgg agccgcgctc
    10081 gttgtgatcg ctgccctgct ggttagcggc ctgcgtattg ctttaccgca tcttgacgcc
    10141 tggcgtccgg aaatcctcaa caaaatagaa tccgcgactg gcatgccggt agaagccagt
    10201 cagctctcag ccagctggca gaattttggc ccgacgcttg aagcacacga catccgtgca
    10261 gaactaaaag atggcggcga attttcggtt aaacgcgtta ctctggcgct ggatgtctgg
    10321 cagagcctgt tacatatgcg ctggcagttt cgcgacctca ctttctggca gctgcgcttt
    10381 cgcaccaaca ctcctatcac cagcggtggt agtgatgaca gtctggaagc cagtcacatc
    10441 agcgatctgt ttcttcgtca atttgaccat ttcgatcttc gcgacagtga agtcagtttc
    10501 ctgacgccat ccggtcagcg cgccgagctg gcgatcccac aactcacctg gctgaacgat
    10561 ccacgtcgac accgtgcgga aggcctggta agcctctcca gccttaccgg acagcacggc
    10621 gtgatgcagg tgcgcatgga tttgcgcgat gatgaggggt tgttaagcaa tggtcgcgtc
    10681 tggctccagg cggatgacat cgacctgaag ccgtggctcg gtaaatggat gcaggacaat
    10741 attgcgctgg aaacggcaca gttctccctt gaaggctgga tgacgatcga caaaggcgat
    10801 gtaaccggcg gtgacgtctg gctgaaacag ggcggtgcca gctggttggg cgagaagcaa
    10861 acgcatacgc tgtcggtgga taatctgacc gcgcatatta cgcgtgaaaa tccgggctgg
    10921 cagttctcta ttcccgatac acggatcacg atggacggca aaccctggcc gagcggagca
    10981 ttgacgctgg cctggatacc ggaacaggac gttggcggca aagacaataa acgcagtgac
    11041 gaactccgga ttcgcgccag taatctggag ctggcaggcc tggagggcat acgcccgctg
    11101 gccgcgaaac tttcacctgc actgggtgat gtttggcgct ccacacaacc gagcggcaag
    11161 attaacactc tggcgctgga tatcccgctt caggcggcag acaagacccg ttttcaggca
    11221 tcgtggagcg atctggcctg gaagcaatgg aaattattac cgggtgcgga acacttctcc
    11281 gggacgcttt ccggcagcgt tgaaaatggt ttgcttaccg cgtcgatgaa gcaggcaaag
    11341 atgccttacg aaacggtatt ccgtgcgcca ctagaaatcg ccgacggcca ggcaactata
    11401 agctggctga acaataacaa aggtttccag ctggatgggc gtaatattga cgttaaagcc
    11461 aaagccgtcc atgcgcgcgg cggttttcgt tacctgcaac ctgctaacga tgaaccctgg
    11521 ctgggtattc tggctggcat cagtaccgat gatggttcac aagcctggcg ctatttcccg
    11581 gaaaacttga tgggtaaaga cctggttgat tacttaagtg gcgcgattca gggcggtgaa
    11641 gcggataacg cgacgctggt ttatggtggc aatccgcaac tcttccccta taaacacaac
    11701 gaaggtcagt ttgaagtgct ggtgccgctg cgcaacgcga agtttgcctt ccagccggac
    11761 tggcctgcat taactaacct tgatattgaa ctggacttta ttaacgacgg tttatggatg
    11821 aaaaccgatg gcgttaatct gggcggcgtg cgcgcgagta atcttaccgc agtgatccct
    11881 gactactcaa aagaaaaact gctgattgac gctgacatta aaggtccggg taaagccgtt
    11941 ggcccttact ttgatgagac accgctgaaa gattctctgg gtgcgaccct gcaagaactc
    12001 cagctcgacg gcgatgtgaa tgctcgctta catcttgata tcccgctgaa cggcgaactg
    12061 gtaaccgcga aaggtgaagt gacgctgcgt aataacagtc tgtttatcaa accactcgac
    12121 agcaccctga aaaatttgag cggtaaattc agctttatca atagcgatct gcaaagtgaa
    12181 ccactgacag caagctggtt taatcagccg ttgaacgtgg atttttccac caaagaaggg
    12241 gcaaaagcct accaggtagc ggtaaacctc aacggtaact ggcaaccggc gaaaaccggc
    12301 gttctgcctg aagcggtgaa cgaagcattg agtggcagcg tggcgtggga tggtaaagtg
    12361 ggcattgatc tgccttatca tgctggtgcg acctataaca tagagctgaa cggcgatcta
    12421 aagaatgtga gcagtcactt accttcaccg ttagccaaac ctgcgggtga accactagcg
    12481 gtaaacgtta aggttgatgg caatctcaac agctttgaat taaccggaca ggctggtgcg
    12541 gataatcatt tcaatagccg ctggttgctc ggtcaaaagc tgacgctcga tcgtgctatt
    12601 tgggcggcag acagtaaaac gctcccgccg ttgccggaac aaagtggcgt tgaactcaat
    12661 atgccgccga tgaatggtgc cgagtggctg gccctgttcc agaaaggcgc tgcggagagt
    12721 gtcggtggtg cagcgagttt cccacaacac ataacgttac gtacgcctat gttgtcactg
    12781 ggaaatcagc aatggaataa cctgagtatt gtttcgcaac cgacggcaaa tggcaccctg
    12841 gttgaagcgc aagggcgtga aatcaacgcc acgctagcga tgcgtaataa cgcgccgtgg
    12901 ctggcgaata tcaaatatct ttattacaac ccgagcgtgg cgaaaactcg tggtgattca
    12961 acgccgtcat cacctttccc gacaacggag cgcattaact tccgtggctg gccggacgcc
    13021 caaatacgat gcacagagtg ctggttctgg gggcaaaaat tcggtcgcat tgacagtgat
    13081 atcaccattt ctggcgatac gttaacgctg accaatggac tgattgatac tggtttctcg
    13141 cggcttactg ccgatggtga atgggttaat aatccgggga atgaacgtac ctcgctgaaa
    13201 ggaaaactgc gcgggcagaa aattgatgcc gccgcagaat tttttggtgt cacgacgccc
    13261 atacgccagt cgtcatttaa tgtggattac gatttacact ggcgcaaagc accctggcag
    13321 ccagatgaag cgacgttgaa tggcatcatt catactcaac tgggtaaagg cgaaattacc
    13381 gaaatcaata ccggacatgc cgggcaattg ctgcgcttat tgagcgtaga tgccctgatg
    13441 cgtaagctgc gttttgattt cagagacact tttggcgaag ggttctattt tgactccatt
    13501 cgcagcaccg cgtggattaa agacggcgtt atgcacaccg acgacacgct ggtggatggc
    13561 ctggaggcgg atatcgccat gaaagggtcg gtaaatctgg tacgtcgcga cctgaatatg
    13621 gaagcggttg tcgcaccaga gatttctgcg acggtgggcg tggctgcggc ttttgcggtt
    13681 aaccccattg ttggcgcggc agtgtttgcc gccagtaaag tgctggggcc gctgtggagc
    13741 aaagtctcca ttttgcgcta tcacatttcg ggtccgctgg acgatccgca aatcaacgaa
    13801 gtgttgcgcc aaccgcgtaa agaaaaagcg caatgatttg acgagggcgc gtaattgccc
    13861 caatctcata ggataatcgt tgccaaaggc caacgagcca gaacataacc gtaggtcgga
    13921 tagggcgtt
//
LOCUS       DACAOP010000110        13822 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.110, whole genome shotgun sequence.
ACCESSION   DACAOP010000110 DACAOP010000000
VERSION     DACAOP010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13822
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.110"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(76..966)
                     /gene="alsR"
                     /locus_tag="IT892_003745"
                     /gene_synonym="rpiR"
     CDS             complement(76..966)
                     /gene="alsR"
                     /locus_tag="IT892_003745"
                     /gene_synonym="rpiR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418513.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="als operon DNA-binding transcriptional repressor
                     AlsR"
                     /protein_id="HAP3136905.1"
                     /translation="MSQSEFDSALPNGIGLAPYLRMKQEGMTENESRIVEWLLKPGNL
                     SCAPAIKDVAEALAVSEAMIVKVSKLLGFSGFRNLRSALEDYFSQSEQVLPSELAFDE
                     APQDVVNKVFNITLRTIMEGQSIVNVDEIHRAARFFYQARQRDLYGAGGSNAICADVQ
                     HKFLRIGVRCQAYPDAHIMMMSASLLQEGDVVLVVTHSGRTSDVKAAVELAKKNGAKI
                     ICITHSYHSPIAKLADYIICSPAPETPLLGRNASARILQLTLLDAFFVSVAQLNIEQA
                     NINMQKTGAIVDFFSPGALK"
     gene            1325..1774
                     /gene="rpiB"
                     /locus_tag="IT892_003746"
     CDS             1325..1774
                     /gene="rpiB"
                     /locus_tag="IT892_003746"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional allose-6-phosphate
                     isomerase/ribose-5-phosphate isomerase RpiB"
                     /protein_id="HAP3136906.1"
                     /translation="MKKIAFGCDHVGFILKHEIVAHLVERGVEVIDKGTWSSERTDYP
                     HYASQVALAVAGGEVDGGILICGTGVGISIAANKFAGIRAVVCSEPYSAQLSRQHNDT
                     NVLAFGSRVVGLELAKMIVDAWLGAQYEGGRHQQRVEAITAIEQRRN"
     gene            1843..2172
                     /gene="yjdP"
                     /locus_tag="IT892_003747"
     CDS             1843..2172
                     /gene="yjdP"
                     /locus_tag="IT892_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YjdP"
                     /protein_id="HAP3136907.1"
                     /translation="MKRFPLFLLFTLLTLSTVPAQADIIDDTIGNIQQAINDAYNPDR
                     GRDYEDSRDDGWQREVSDDRRRQYDDRRRQFEDRRRQLDDRQRQLDQERRQLEDEERR
                     MEDEYGR"
     gene            complement(2319..3077)
                     /gene="phnP"
                     /locus_tag="IT892_003748"
     CDS             complement(2319..3077)
                     /gene="phnP"
                     /locus_tag="IT892_003748"
                     /EC_number="3.1.4.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein PhnP"
                     /protein_id="HAP3136908.1"
                     /translation="MSLTLTLTGTGGAQGVPAWGCECAACARARRSPQYRRQPCSGVV
                     KFNDAITLIDAGLHDLADRWSPGSFQQFLLTHYHMDHVQGLFPLRWGVGDPIPVYGPP
                     DEQGCDDLFKHPGLLDFSHTVEPFVVFDLQGLQVTPLPLNHSKLTFGYLLETAHSRVA
                     WLSDTAGLPEKTLKFLRNNQPQVMVMDCSHPPRADAPRNHCDLNTVLALNQVIRSPRV
                     ILTHISHQFDAWLMENALPSGFEVGFDGMEIGVA"
     gene            complement(3079..3513)
                     /gene="phnO"
                     /locus_tag="IT892_003749"
     CDS             complement(3079..3513)
                     /gene="phnO"
                     /locus_tag="IT892_003749"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoalkylphosphonate N-acetyltransferase"
                     /protein_id="HAP3136909.1"
                     /translation="MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRD
                     PNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAE
                     EEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL"
     gene            complement(3500..4057)
                     /gene="phnN"
                     /locus_tag="IT892_003750"
     CDS             complement(3500..4057)
                     /gene="phnN"
                     /locus_tag="IT892_003750"
                     /EC_number="2.7.4.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 1,5-bisphosphokinase"
                     /protein_id="HAP3136910.1"
                     /translation="MMGKLIWLMGPSGSGKDSLLAELRLREQTQLLVAHRYITRDASA
                     GSENHIALSEQEFFTRAGQNLLALSWHANGLYYGVGVEIDLWLHAGFDVLVNGSRAHL
                     PQARARYQSALLPVCLQVSPEILRQRLENRGRENASEINARLARAARYTPQDCHTLNN
                     DGSLRQSVDTLLTLIHQKEKHHACL"
     gene            complement(4057..5193)
                     /gene="phnM"
                     /locus_tag="IT892_003751"
     CDS             complement(4057..5193)
                     /gene="phnM"
                     /locus_tag="IT892_003751"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HAP3136911.1"
                     /translation="MIINNVKLVLENEVVSGSLEVQNGEIRAFAESQSRLPEAMDGEG
                     GWLLPGLIELHTDNLDKFFTPRPKVDWPAHSAMSSHDALMVASGITTVLDAVAIGDVR
                     DGGDRLENLEKMINAIEETQKRGVNRAEHRLHLRCELPHHTTLPLFEKLVQREPVTLV
                     SLMDHSPGQRQFANREKYREYYQGKYSLTDAQMQQYEEEQLALAARWSQPNRESIAAL
                     CRARKIALASHDDATHAHVAESHQLGSVIAEFPTTFEAAEASRKHGMNVLMGAPNIVR
                     GGSHSGNVAASELAQLGLLDILSSDYYPASLLDAAFRVADDQSNRFTLPQAVKLVTKN
                     PAQALNLQDRGVIGEGKRADLVLAHRKDNHIHIDHVWRQGKRVF"
     gene            complement(5190..5870)
                     /gene="phnL"
                     /locus_tag="IT892_003752"
     CDS             complement(5190..5870)
                     /gene="phnL"
                     /locus_tag="IT892_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HAP3136912.1"
                     /translation="MINVQNVSKTFILHQQNGVRLPVLNRASLTVNAGECVVLHGHSG
                     SGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVI
                     PRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNI
                     ARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKTRGAAIVGIFHDEAVRNDVADR
                     LHPMGASS"
     gene            complement(5981..6739)
                     /gene="phnK"
                     /locus_tag="IT892_003753"
     CDS             complement(5981..6739)
                     /gene="phnK"
                     /locus_tag="IT892_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnK"
                     /protein_id="HAP3136913.1"
                     /translation="MNQPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGK
                     TTLLKSISARLTPQQGEIHYENRSLYAMSEADRRRLLRTEWGVVHQHPLDGLRRQVSA
                     GGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
                     VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLV
                     MKQGQVVESGLTDRVLDDPHHPYTQLLVSSVLQN"
     gene            complement(6736..7581)
                     /gene="phnJ"
                     /locus_tag="IT892_003754"
     CDS             complement(6736..7581)
                     /gene="phnJ"
                     /locus_tag="IT892_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HAP3136914.1"
                     /translation="MANLSGYNFAYLDEQTKRMIRRAILKAVAIPGYQVPFGGREMPM
                     PYGWGTGGIQLTASVIGESDVLKVIDQGADDTTNAVSIRNFFKRVTGVNTTERTDDAT
                     VIQTRHRIPETPLTEDQIIIFQVPIPEPLRFIEPRETETRTMHALEEYGVMQVKLYED
                     IARFGHIATTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPP
                     FTRVESLDFDDHPFTVQQWDEPCAICGSTHSYLDEVVLDDAGNRMFVCSDTDYCRQQS
                     EAKNQ"
     gene            complement(7574..8638)
                     /gene="phnI"
                     /locus_tag="IT892_003755"
     CDS             complement(7574..8638)
                     /gene="phnI"
                     /locus_tag="IT892_003755"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate synthase subunit PhnI"
                     /protein_id="HAP3136915.1"
                     /translation="MYVAVKGGEKAIDAAHALQESRRRGDTDLPELSVAQIEQQLNLA
                     VDRVMTEGGIADRELAALALKQASGDNVEAIFLLRAYRTTLAKLAVSEPLDTTGMRLE
                     RRISAVYKDIPGGQLLGPTYDYTHRLLDFTLLANGEAPTLTTADSEQQPSPHVFSLLA
                     RQGLAKFEEDSGAQPDDITRTPPVYPCSRSSRLQQLMRGDEGYLLALAYSTQRGYGRN
                     HPFAGEIRSGYIDVSIVPEELGFAVNVGELLMTECEMVNGFIDPPGEPPHFTRGYGLV
                     FGMSERKAMAMALVDRALQAPEYGEHATGPAQDEEFVLAHADNVEAAGFVSHLKLPHY
                     VDFQAELELLKRLQQEQNHG"
     gene            complement(8638..9222)
                     /gene="phnH"
                     /locus_tag="IT892_003756"
     CDS             complement(8638..9222)
                     /gene="phnH"
                     /locus_tag="IT892_003756"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HAP3136916.1"
                     /translation="MTLETAFMLPVQDAQHSFRRLLKAMSEPGVIVALHQLKRGWQPL
                     NIATTSVLLTLADNDTPVWLSTPLNNDIVNQSLRFHTNAPLVSQPEQATFAVTDEAIS
                     SEQLNALSTGTAVAPEAGATLILQVASLSGGRMLRLTGAGIAEERMIAPQLPECILHE
                     LTERPHPFPLGIDLILTCGERLLAIPRTTHVEVC"
     gene            complement(9219..9671)
                     /gene="phnG"
                     /locus_tag="IT892_003757"
     CDS             complement(9219..9671)
                     /gene="phnG"
                     /locus_tag="IT892_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HAP3136917.1"
                     /translation="MHADTATRQHWMSVLAHSQPAELAARLNALNITADYEVIRAAET
                     GLVQIQARMGGTGERFFAGDATLTRAAVRLTDGTLGYSWVQGRDKQHAERCALIDALM
                     QQSRHFQNLSETLIAPLDADRMARIAARQAEVNASRVDFFTMVRGDNA"
     gene            complement(9672..10397)
                     /gene="phnF"
                     /locus_tag="IT892_003758"
     CDS             complement(9672..10397)
                     /gene="phnF"
                     /locus_tag="IT892_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism transcriptional regulator
                     PhnF"
                     /protein_id="HAP3136918.1"
                     /translation="MHLSTHPTSYPTRYQEIAAKLEQELRQHYRCGDYLPAEQQLAAR
                     FEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMRPFDYPLNAQARFSQNLLDQGSHPT
                     SEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGVALCLIDHYFADLTLWPTLQ
                     RFDSGSLHDFLREQTGIALRRSQTRISARRAQAKECQRLEIPNMSPLLCVRTLNHRDG
                     ESSPAEYSVSLTRADMIEFTMEH"
     gene            complement(10418..11205)
                     /gene="phnE"
                     /locus_tag="IT892_003759"
                     /pseudo
     CDS             complement(10418..11205)
                     /gene="phnE"
                     /locus_tag="IT892_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313113.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
     gene            complement(11311..12327)
                     /gene="phnD"
                     /locus_tag="IT892_003760"
     CDS             complement(11311..12327)
                     /gene="phnD"
                     /locus_tag="IT892_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3136919.1"
                     /translation="MNAKIIASLAFTSMFSLSTLLSPAHAEEQEKALNFGIISTESQQ
                     NLKPQWTPFLQDMEKKLGVKVNAFFAPDYAGIIQGMRFNKVDIAWYGNLSAMEAVDRA
                     NGQVFAQTVAADGSPGYWSVLIVNKDSPINNLNDLLAKRKDLTFGNGDPNSTSGFLVP
                     GYYVFAKNNISASDFKRTVNAGHETNALAVANKQVDVATNNTENLDKLKTSAPEKLKE
                     LKVIWKSPLIPGDPIVWRKNLSETTKDKIYDFFMNYGKTPEEKAVLERLGWAPFRASS
                     DLQLVPIRQLALFKEMQGVKSNKGLNEQDKLAKTTEIQAQLDDLDRLNNALSAMSSVS
                     KAVQ"
     gene            complement(12352..13140)
                     /gene="phnC"
                     /locus_tag="IT892_003761"
     CDS             complement(12352..13140)
                     /gene="phnC"
                     /locus_tag="IT892_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HAP3136920.1"
                     /translation="MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKS
                     TLLRHLSGLITGDKSVGSHIELLGRTVQREGRLARDIRKSRAHTGYIFQQFNLVNRLS
                     VLENVLIGALGSTPFWRTCFSWFTGEQKQRALQALTRVGMVHFAHQRVSTLSGGQQQR
                     VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALR
                     YCERIVALRQGHVFYDGSSQQFDNERFDHLYRSINRVEENAKAA"
     gene            complement(13273..13716)
                     /gene="yjdN"
                     /locus_tag="IT892_003762"
     CDS             complement(13273..13716)
                     /gene="yjdN"
                     /locus_tag="IT892_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family metalloprotein YjdN"
                     /protein_id="HAP3136921.1"
                     /translation="MPLSPYLSFAGNCSDAIAYYQRTLGAELLYKISFGEMPKSAQDS
                     AENCPSGMQFPDTAIAHANVRIAGSDIMMSDAMPSGKASYSGFTLVLDSQQVEEGKRW
                     FDNLAANGKIEMAWQETFWAHGFGKVTDKFGVPWMINVVKQQPTQ"
BASE COUNT         2804 a         3843 c         4120 g         3055 t
ORIGIN      
        1 ttcagatatt tattcataat aatgttctca cggtaagggg acaggtaact ccgcgatggc
       61 ggaattacct ttttcttatt tcagcgcgcc tggtgagaag aaatcaacaa ttgcgccggt
      121 tttttgcata ttaatattag cttgttcaat gttgagctgg gcgacagaga caaaaaaagc
      181 gtccagcaaa gttagttgta atattcttgc cgaggcatta cgacctaata acggcgtttc
      241 cggggctggt gagcaaataa tataatcggc cagtttcgct atcggtgaat ggtagctatg
      301 ggttatacaa ataatctttg ccccgttctt ttttgccagt tctacggccg cttttacatc
      361 actggttcgc ccggaatggg tcactaccag cacaacatct ccttcctgta acaacgaagc
      421 ggacatcatc atgatgtgag catcaggata ggcctgacag cgtacgccaa tgcgcaagaa
      481 cttgtgctgt acatcagcac agatagcatt tgatcctccg gcaccgtaca aatcccgctg
      541 tctggcctga tagaaaaagc gggcggcacg gtggatctca tcaacgttga cgatcgactg
      601 accttccata atggtgcgta aagtgatgtt aaatacctta ttcaccacat cctgcggcgc
      661 ttcatcaaaa gccaactcgg aaggcaatac ctgttctgac tgagaaaaat aatcttccag
      721 cgcactgcgt aagttacgaa agccgctaaa ccccagcagc tttgatacct taactatcat
      781 cgcttcagat accgccagag cttctgcgac atctttaatt gcgggtgcac aactcaggtt
      841 accgggtttg agtaaccact ccacgatgcg gctttcattt tctgtcattc cttcctgctt
      901 cattcgcagg taaggcgcta accctatacc gttcggaagc gctgaatcaa actctgactg
      961 gctcatcacg ttctcttgtc cttgaattga agacgccact atatcaccac agcaagaaca
     1021 gaaaagatgc tggcgacttc acaaaaaaat aaaatttata aagtttattt tattgtgaac
     1081 aatggcgagt ggcttaaaat tttatttcat ttaattagtt taaaaacatg atgttatttg
     1141 tttttctggt tttttagatg atagatgttg ctggatggtg agtgtcttta acgctattgc
     1201 gctgtcagat gtaactctgt aaaacagatc aggaaggcgt aattcatcga ttttgggtgt
     1261 ttttaattca ttaacatcac aaatgttttt tgattgtgaa gttttgcacg gacggggaag
     1321 atgaatgaaa aagattgcat ttggctgtga tcatgtcggt ttcattttaa aacatgaaat
     1381 agtggcacat ttagttgagc gtggcgttga agtgattgat aaaggaacct ggtcgtcaga
     1441 gcgtactgat tatccacatt acgccagtca agtcgcactg gctgttgctg gcggagaggt
     1501 tgatggcggg attttgattt gtggtactgg cgtcggtatt tcgatagcgg cgaacaagtt
     1561 tgccggaatt cgcgcggtcg tctgtagcga accttattcc gcgcaacttt cgcggcagca
     1621 taacgacacc aacgtgctgg cttttggttc acgagtggtt ggcctcgaac tggcaaaaat
     1681 gattgtggat gcgtggctgg gcgcacagta cgaaggcggt cgtcatcaac aacgcgtgga
     1741 ggcgattacg gcaatagagc agcggagaaa ttgagattca tccactactt gcatggatga
     1801 gtaatgatta atgtggatag agtttctttt tgaggttggc taatgaaacg ctttccgcta
     1861 tttcttttat tcaccctgct cacgctgtcc accgttccgg cccaggccga tattatcgac
     1921 gacaccattg gcaatattca gcaggcgatt aatgacgctt ataaccctga ccgtgggcga
     1981 gactatgaag attcgcgcga cgacggctgg cagcgtgaag tgagcgacga tcggcgcaga
     2041 caatatgacg accgccgccg ccagtttgaa gatcgccgca ggcagctgga cgatcgccag
     2101 cgccagcttg atcaggagcg tcggcaactg gaggatgaag agcggagaat ggaagatgag
     2161 tatgggcgat gaggttgggt atggagcagg catcgcccct caccccaatg gggagaggga
     2221 gaaaacgagc gcaatattca atatcgagca caatcggtcc cctcgcccct ctggggagag
     2281 ggttagggtg agggggccag cgcgcacatt ccctctcatc acgccacccc aatctccatc
     2341 ccatcaaacc ccacctcaaa ccctgacggt agtgcgtttt ccatcagcca cgcatcaaac
     2401 tggtggctga tatgggtcag aatcacccgt ggcgagcgga taacctgatt cagcgcaagc
     2461 acggtattta aatcacagtg attacgcggt gcatccgcgc gcggcgggtg actgcaatcc
     2521 atcaccatta cctgcggctg attattgcgt aaaaatttca gcgttttttc cggcaagcct
     2581 gcggtgtcag acagccatgc cacccggctg tgtgccgttt ccagcagata accgaaggtc
     2641 agttttgagt ggttgagcgg caggggcgtg acctgtaacc cctgcaaatc aaacaccaca
     2701 aacggttcca ccgtgtggct gaaatcaagc aggcccggat gtttaaacag atcgtcgcag
     2761 ccctgttcat ccggcgggcc gtaaaccggg atcggatcgc caacgcccca gcgcagcgga
     2821 aacagcccct ggacgtgatc catatgataa tgcgtcagca aaaactgctg gaacgatccg
     2881 ggcgaccagc gatcggcgag atcgtgcagc ccggcgtcga tcagggtgat tgcgtcgtta
     2941 aacttcacta cgccgctgca cggttggcgg cgatactgcg gcgagcgccg cgctctggcg
     3001 caggccgcac actcgcagcc ccatgccgga acgccctgtg cgccgccggt gccggtgagc
     3061 gtgagggtca ggctcatgtt acagcgcctt ggtgaagcgg aagtggctct gctcgtagcc
     3121 ttcgcgcaga tagaaacggt gcgcgtcgtg gcgcttcacg ttggtcgaaa gttcggtcat
     3181 ttcggccccg gcctggcggg cttcttcttc tgcccacgcc agtaacttac tgccgacgtt
     3241 cagaccgcgc gcctgcggca ttaccaccaa ctcctgaatt tcgccgatcc agttgacatg
     3301 atgcagatga aactgcaaat gcaggccgat catgccgaca acttcgccat caagcagcgc
     3361 cagatggtag cgcatgtttg ggtcgcgcag attggcgtta aaacccacgc gaaacgcgtg
     3421 gtggtcaaac tccgcctgtt ttagctcaca aatcagcgcg taaaccgcgt cggtgtcgta
     3481 ctgcgtggcc gggcgaagct cacaagcagg catggtgttt ctccttctga tggatcagcg
     3541 tcagcagcgt gtcgaccgac tggcgcaggc tgccgtcatt gttgagcgta tggcaatcct
     3601 gtggagtata gcgggcggcg cgcgccaggc gggcgttaat ttcactggcg ttttcacggc
     3661 cacggttttc caggcgctgg cggaggatct ccggcgaaac ctgtaaacag acgggcagca
     3721 gcgccgattg atagcgcgcc cgcgcctgcg gcagatgggc gcgtgagccg ttgaccagca
     3781 cgtcgaatcc ggcgtgcagc cagagatcaa tctcgacgcc gacgccataa tacagaccgt
     3841 tagcgtgcca gcttaaggcc aacagatttt gccccgcgcg ggtaaaaaac tcctgctcgc
     3901 tcagggcgat atggttttca cttccggcgc tggcatcgcg cgtgatgtag cgatgcgcca
     3961 ccagtaactg agtttgttcc cgcaggcgga gttccgccag caggctgtct ttcccggagc
     4021 cggacggccc cattaaccaa atcagttttc ccatcatcag aacacccttt taccctgacg
     4081 ccagacgtgg tcgatatgaa tatgattgtc cttgcgatgc gccagcacca ggtcggcgcg
     4141 tttgccctcg ccaatcaccc cgcgatcctg gagattaagc gcctgcgctg gatttttagt
     4201 caccagcttc accgcctgcg gcagcgtaaa gcggttgctc tggtcatcgg cgacgcgaaa
     4261 tgccgcatcg agcaggctgg cggggtagta gtcggaagag aggatatcca gcaggccaag
     4321 ctgcgccagt tcactggccg ccacgttgcc ggagtgcgag ccgccgcgca caatattcgg
     4381 cgcgcccatc agcacgttca tgccatgctt gcgcgaggct tccgccgctt cgaacgtggt
     4441 gggaaattcg gcgatcacgc tgccaagctg gtgagattca gcaacgtggg cgtgggtggc
     4501 gtcatcgtgg ctggcaagcg caatttttcg cgcgcggcac agggcggcga tggattcgcg
     4561 attcggctgc gaccagcgtg cggcgagcgc cagttgctct tcttcgtact gctgcatctg
     4621 cgcatcagtg agggagtatt tgccctgata atattcgcga tacttctcgc ggttggcgaa
     4681 ctggcgctgg cccggcgagt ggtccatcag cgacaccagc gtcaccggct cgcgctgcac
     4741 cagtttttca aacagcggca gcgtggtgtg atgcggcagt tcgcagcgca gatgcagacg
     4801 gtgctcggcg cggttgacgc cgcgtttctg cgtctcttcg atggcgttga tcatcttctc
     4861 cagattctcc agccgatcgc cgccgtcgcg cacgtcgcca attgccacgg catccagtac
     4921 ggtggtgatg ccgctcgcca ccatcagcgc gtcgtggctg ctcatcgccg agtgggcagg
     4981 ccagtcaact ttcgggcgcg gggtgaagaa tttatccaga ttatcggtat gcagctcaat
     5041 cagccccggc agcagccagc cgccttcgcc gtccatcgcc tccggcaggc ggctctggct
     5101 ttcggcaaag gcgcggattt cgccgttctg cacctccagc gaaccgctta ccacctcgtt
     5161 ttccagcacc agcttaacgt tattgataat catgaagagg ctcccattgg gtgcaggcgg
     5221 tcggcgacgt cattacgtac agcttcgtca tggaagatgc ctacgatggc tgcgccacgg
     5281 gttttggctt cgcgaatcag ttccaccacc gcggcgctgt ttttggcgtc cagcgaggcg
     5341 gtaggttcgt caagcagcag aatggggtag tcgacgataa agccgcgggc gatgttgacg
     5401 cgctgctgtt cgccaccgga aaatgtcgat ggtgccaggt gccacaggcg ttccggcacg
     5461 ttcaggcggg tgagaagacg cgcggcttta gcggcgcagg cttcacgcgg aacgccggta
     5521 tcgagcagcg gctgcatcac cacttccagt gctgagatac gcgggatgac gcgcagaaac
     5581 tggctcaccc agccgacggt ggttttgcgg atttccacca ctttgcgcgc tggcgcggtg
     5641 accaggtcta cccactcgtc accgtgtttg atctggattt gaccttcgtc gggcagatag
     5701 ttggcgtaca gcgagcgtag cagagttgat ttgccgctgc cggaatggcc gtggagcacc
     5761 acgcattcgc ccgcgttgac ggtgagcgag gcgcgattga ggacgggcag gcgcacgccg
     5821 ttttgctggt gcaggatgaa ggttttactg acgttttgta cgttaatcat ttttcgcctc
     5881 gtggttcggg tgtcggatgc gacgctgacg cgtcttatcc gacctacggg gagcgcattt
     5941 gtaggccgga taaggcgttt acgccgcatc cggcaccggc tcaattctgc aaaaccgatg
     6001 acaccagcag ctgtgtatac ggatgatgcg ggtcgtcgag cacgcggtcg gttaacccac
     6061 tctccaccac ttgcccctgc ttcatcacca gcaaacggtc cgccagcagg cgggcgacgc
     6121 ctaaatcatg ggtgacaatc accaccgcga ggttcagctc caccaccagg ccgcgcagca
     6181 ggtcgagcag gcgggcctgc accgacacat ccagcccgcc ggtcggttca tccataaaca
     6241 ccagcttcgg atgcgtcacc aggttgcggg caatctgcaa acgctgctgc ataccgccgg
     6301 aaaaggtggt cggcaggtcg tcgatccggt tggcgggaat ctccacctct tccagccact
     6361 tctgcgcggt ggcacgaata tcgccgtaat gacgtgcccc ggtcgccatc agccgctcgc
     6421 cgatattgcc gcctgccgac acctggcggc gcaggccgtc gagtggatgc tgatgcacca
     6481 cgccccattc ggtacgcagc aggcgacggc ggtcggcctc gctcattgca tacagcgaac
     6541 ggttctcgta gtgaatttcc ccctgctgcg gcgtcaggcg cgcggagatc gacttcagca
     6601 gcgtggtctt cccggagccg gattccccga caatgcccag cacttccccc ggccataaat
     6661 caaaagagac atcgctaaag cctttgcccg gcgcgtaaag gtgggtcagg ttattgaccg
     6721 aaagtaacgg ttgattcatt ggttttttgc ctcgctctgt tggcggcaat aatcggtatc
     6781 ggagcagaca aacatgcggt ttccggcgtc atccagcacc acttcatcaa gatagctgtg
     6841 ggtcgatccg cagatggcgc atggctcatc ccactgctga acggtgaacg ggtgatcgtc
     6901 gaaatcgaga ctttccacgc gggtaaacgg cggcaccgca tagatgcgct tctcgcgccc
     6961 cgcgccgaac agttgcaggg cgggcatcat gtccattttt gggttatcga atttcgggat
     7021 cggcgacggg tccatcacgt agcgcccatt taccttcacc ggataggcgt aggtggtggc
     7081 gatatgaccg aagcgggcga tatcttcata cagtttcacc tgcatcacgc cgtactcttc
     7141 cagcgcgtgc atggtgcggg tttccgtttc gcgcggctcg ataaagcgca gcggctcggg
     7201 gattggcacc tggaagataa ttatctgatc ttcggtcagc ggcgtttcgg ggatgcggtg
     7261 acgcgtctgg ataaccgtcg catcgtccgt acgttccgtg gtgtttaccc cggtcacgcg
     7321 cttgaagaag ttgcgaatcg acacggcgtt ggtggtgtca tccgcgccct ggtcaatcac
     7381 cttcagcacg tcgctttcgc caatcacgct ggcggtaagc tgaatgccgc cggttcccca
     7441 gccgtacggc atcggcatct cgcgcccgcc aaacggcacc tgataaccgg ggatcgccac
     7501 cgcttttaag atggcgcggc ggatcatgcg tttggtctgc tcgtcgaggt aggcaaagtt
     7561 gtagccgctc agattagcca tggttctgct cctgttgcag acgtttgagt agctccagtt
     7621 cggcctggaa atcgacgtag tgggggagtt tgaggtgtga gacaaagcct gcggcttcga
     7681 cgttgtcggc atgtgccagc acgaactctt catcctgcgc cgggcctgtc gcgtgctcgc
     7741 cgtactccgg ggcttgcaga gcgcggtcga ccagcgccat cgccatcgct ttgcgctcgc
     7801 tcatgccgaa caccagcccg tagccgcgcg tgaagtgcgg cggctcaccc ggcgggtcga
     7861 taaaaccgtt aaccatttca cactcagtca tcagcagttc gccgacgttc accgcaaatc
     7921 ccagctcttc cggcacaatc gacacgtcga tatagccgct gcggatctcg cctgcgaacg
     7981 ggtgattgcg cccgtaaccg cgttgggtgg agtaggccag cgccagcaaa tagccttcgt
     8041 cgccgcgcat caactgctgc aaacgggagg agcgtgagca ggggtaaacc ggcggcgtgc
     8101 gggtgatgtc atccggctgt gcgccgctat cctcttcaaa cttcgccagc ccctgacgcg
     8161 ccagcaggct gaaaacgtgc ggcgacggct gctgttcgct gtcggcggtg gtcagcgtcg
     8221 gcgcttcgcc gtttgccagc agggtaaaat cgagcaggcg atgggtgtag tcgtaggttg
     8281 ggccaagcag ctggccgccg ggaatgtctt tataaacggc ggagatacgg cgttcgagac
     8341 gcatcccggt ggtgtcgagc ggctcgctta ccgccagctt cgccaacgtg gtgcggtagg
     8401 cgcgcagcag gaaaatcgct tcaacgttat cgccgctggc ctgtttcagc gccagcgccg
     8461 ccagttcgcg gtcggcaatg ccgccttcgg tcatcacgcg atctaccgcg aggttaagct
     8521 gctgttcaat ctgggcgacg ctcagttcgg gcaaatcggt atcgcctcgg cgtcggctct
     8581 cttgcagggc gtgggcggcg tcgatcgcct tctcgccccc tttcacggca acgtacatca
     8641 gcacacctcc acatgagtgg ttcgcggaat agccagcagg cgctcgccac aggtcaggat
     8701 caggtcgatg ccgagcggga acggatgcgg gcgctcggtg agttcgtgca gaatgcactc
     8761 cggcagctgc ggagcgatca ttcgttcttc ggcaataccc gcaccagtaa ggcgcaacat
     8821 gcgtccgccg ctcaggctgg cgacctgtaa aatcagcgtc gcacccgctt ccggcgcaac
     8881 ggcggtgccg gtggaaaggg cgttgagctg ttcgctggaa atcgcctcat ccgtcaccgc
     8941 gaaggtcgcc tgttccggct ggctgaccag cggcgcgttg gtatgaaaac gcaggctctg
     9001 gttgacgata tcgttattta atggggtaga aagccacacc ggcgtgtcgt tatcggccag
     9061 cgtcagcagc acgctggtgg tggcgatatt cagcggttgc cagccgcgtt tgagctgatg
     9121 cagggcgaca atcacgcccg gctcgctcat ggcctttaac aggcgacgaa aactgtgctg
     9181 ggcatcctgc acgggaagca taaaagcggt ttccagggtc atgcgttgtc tccgcgaacc
     9241 atcgtaaaga agtcgacccg gctggcgttc acttcggcct ggcgtgcggc aatgcgtgcc
     9301 atacggtcag cgtccagcgg ggcaataagg gtttctgata agttttgaaa gtggcgagat
     9361 tgctgcatca gcgcgtcaat cagcgcgcag cgttcggcgt gctgtttatc acgcccctgc
     9421 acccagctgt agccgagcgt gccgtcagtc aggcgcacgg cggcgcgggt cagcgtggcg
     9481 tcgccggcaa aaaaacgttc gccggtgccg cccattcgcg cctgaatctg taccaggcca
     9541 gtttcagcgg cgcggatcac ctcatagtcg gcggtgatgt ttagcgcgtt caggcgtgct
     9601 gccagttcag ccggttggct gtgcgccagc acggacatcc agtgctggcg ggtcgcggta
     9661 tctgcgtgca ttcagtgctc catagtgaat tcaatcatgt cggcgcgcgt caggctgacg
     9721 gagtactccg ccgggctgct ttcaccgtca cggtggttaa gggtgcgcac gcacagcagc
     9781 ggcgacatat tcgggatttc aagacgctgg cactctttgg cctgggcgcg gcgggcgctg
     9841 atccgcgtct ggctgcggcg cagcgcaatt ccggtttgct cgcgcagaaa atcgtgcagc
     9901 gagccgctgt cgaagcgttg cagcgtcggc cagagggtga ggtccgcgaa gtagtggtcg
     9961 attaaacaga gcgcgacgcc gttgacacga cgcagggtgc gcaggtggat gacgttctcc
    10021 ccctcggtaa tccccagtgc gtcagcgacg tggccggacg cggggcgcaa taccgaaagc
    10081 agtttttcgc tggtgggatg gctgccctga tccagcagat tctggctaaa acgcgcctgg
    10141 gcgttgagcg ggtaatcgaa cgggcgcatc agcaccagca cgccgacgcc ctgacggcgc
    10201 tgtacccagc ctttttccac cagttggtcg atggcgcggc gcagggtgtg gcgattcacc
    10261 tcaaagcgcg ctgccagttg ctgctcggcg ggaagatagt cgccgcagcg gtagtgttga
    10321 cgaagctcct gctcaagttt tgcggctatc tcttgatagc gtgttgggta gctggtcgga
    10381 tgtgtagaca agtgcataga tatcaatgcc tcgcttatca gataaagtgc ttacgcaacc
    10441 gttgagagag gaaatccagc aggctgaccg tgacgatgat aagcaccatc agggcgcagg
    10501 tttgttggaa ctggaaaccg cgaatcgctt cccacagggt gacgccgatc ccgcctgcgc
    10561 cgaccatgcc gacgacggtc gccgagcgga cgttggattc gaagcgatag agggagtagg
    10621 agatcagcag tggcatcacc tgtggcagca cgccgtagag gatctcttcg agcttgttgg
    10681 caccggtggc gcgaatgcct tccaccgggc cgggttcaat cgcttccacc gcttcggaaa
    10741 gcagcttgga gagcacgccg gtggtgtgga taaacagcgc cagcacgcca gcacgccagc
    10801 gaacgggccg aggccgacgg cgaccacgaa cagcatggcg aagaccattt cgttaatggc
    10861 gcggcaggcg tccatcaggc ggcgaacggg ctggtaaacc caccacggca ccaggttttc
    10921 ggcgctcatc aggccaaagg ggatggagag aaccaccgcc agcgcggtgc cccagacggc
    10981 gatttgcagc gtgacggcca tttcggtgag gtaatcctgc cactggctga aatcgggcgg
    11041 gaagaagtcg gcggcgaacg tcgccatgtt gccgccgtct ttgatcagcg taagcggggc
    11101 catttccgcg ccctgccacg agacgaccaa cacggcgagt acaacggccc agctcagaag
    11161 cgagaaccag ctgcgcttgg gtggggcgat ggtgatggtt tgcatgtttg gctccggtct
    11221 gtaggccgga taaggtgctt gcaccgcatc cggcatcaac gcctgcacat tgtcggatgc
    11281 gacgccgggg cgtcttatcc gacctacgat ttactgcacc gctttactca ccgaactcat
    11341 cgcgcttagc gcgttgttca ggcggtccag gtcatccagc tgcgcctgaa tctcggtggt
    11401 ttttgccagc ttgtcctgct cattcagtcc tttattgctt ttcacgccct gcatctcttt
    11461 aaacagcgcg agctggcgaa tcggcaccag ttgcaggtcg ctggaagcgc ggaatggcgc
    11521 ccagcccagg cgttccagca ccgctttttc ttccggcgtt ttgccgtagt tcataaagaa
    11581 gtcgtagatc ttgtctttgg tggtttcgga aagattcttg cgccagacga tcggatcgcc
    11641 tgggatcagc ggcgacttcc agatcacctt cagttctttc agcttctctg gcgcggaggt
    11701 tttcagcttg tcgaggtttt cggtgttgtt ggtggcaaca tccacctgct tgttggcgac
    11761 ggccagcgcg ttggtttcat gcccggcgtt gacggtgcgc ttgaagtcgc tggcggagat
    11821 attgtttttg gcgaagacgt agtagccggg gacgaggaag ccagaggtgg agttaggatc
    11881 gccattgcca aaggtgagat ctttccgctt cgccagcaga tcgttcaggt tgttgatcgg
    11941 actgtctttg ttgacgatca acacgctcca gtaacccggc gatccatccg ccgcgaccgt
    12001 ctgggcgaag acctggccat tggcgcgatc caccgcttcc atcgccgaca gattgccgta
    12061 ccaggcgata tccactttat tgaagcgcat cccctggata atgcccgcgt agtccggggc
    12121 aaagaaggcg ttgaccttca cgcccagctt cttctccata tcctgcaaga acggcgtcca
    12181 ttgcggtttc aggttttgct gtgattccgt tgaaataatg ccgaaattca acgccttttc
    12241 ctgctcttcg gcgtgcgccg ggcttaacag ggtgctgagg ctgaacatgc tggtgaaggc
    12301 cagcgaggca attatcttag cgttcattcg ttttcctcaa tgatggggat gtcaggcagc
    12361 tttcgcgttc tcttcgacgc ggttaatgct gcggtagaga tggtcaaaac gttcgttatc
    12421 aaactgttgg ctgctgccgt cgtagaagac gtgcccctgg cgcagggcga cgatgcgttc
    12481 gcagtagcgc agggcgtaat ccacctgatg cagcgtgacg accacggtga tgccgtcgtt
    12541 ctggttgatg tcgcgcaggg tgtccatcac gatgcgcgct gattctgggt ccagcgaggc
    12601 gatgggttca tcggccagaa tcactttcgc ctgctgcatc agcgcacggg caatcgccac
    12661 acgttgctgc tggccgccgg agagggtgga aacgcgctga tgggcaaaat gcaccatgcc
    12721 aacgcgggtc agcgcctgta acgcgcgctg tttctgctcg ccggtgaacc agctaaaaca
    12781 ggtgcgccag aacggcgtgc tgccgagcgc gccaatcagc acgttctcca gtacgctcag
    12841 gcggttcacc aggttgaatt gttggaatat gtagccggta tgggcgcggc ttttgcggat
    12901 atcgcgggcc aggcggcctt cgcgctggac tgtgcggccc agcagctcga tatggctacc
    12961 gacagattta tcgccggtaa tcaaaccgct taagtgacgt aaaagggtgg attttccgga
    13021 acccgacggc ccaagcagag ccaccatttc accgtgatga atgttcagat caaccgcatg
    13081 cagcgcctga tgctgattga aggttttggc gagcttctcg acacggataa tcgtttgcat
    13141 gatgcagcct ccctaaaaaa gtggctccat cgtggcggat tattgtgacg atttggttaa
    13201 ttaaaagtga ctaacagatg aagagttaac gggaattcga tgacagtgcg ggagggcggg
    13261 cctcccggcg ggttattgcg ttggttgttg tttgacgaca ttaatcatcc acggtacgcc
    13321 aaatttatcg gtgactttgc caaagccatg cgcccagaaa gtttcctgcc aggccatttc
    13381 gatttttccg ttagcggcaa gattgtcaaa ccagcgtttt ccttcttcga cctgttgcga
    13441 atcgagcacc agcgtaaagc cggagtagct ggcttttcct gacggcatgg catcgctcat
    13501 catgatgtcg cttccggcaa tgcgcacatt ggcgtgggcg atggcggtat cgggaaattg
    13561 cattccggaa gggcagttct cggcgctgtc ctgcgctgat tttggcattt cgccgaagct
    13621 gattttatag agcagttccg cgcccaacgt acgttgataa taggcaatcg cgtcggaaca
    13681 gttaccggca aaagagaggt agggacttaa cggcatgatg gtgacctcag ttaagagaag
    13741 ccagttaagt gtagttcgaa atttatacag atgagaggcg gcctgataag acgcgcgagc
    13801 gtcgcatcag gcagtcggca ct
//
LOCUS       DACAOP010000111        13553 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.111, whole genome shotgun sequence.
ACCESSION   DACAOP010000111 DACAOP010000000
VERSION     DACAOP010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13553
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.111"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(6..1375)
                     /locus_tag="IT892_003763"
     CDS             complement(join(6..895,895..1375))
                     /locus_tag="IT892_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611947.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS150 family transposase"
                     /protein_id="HAP3136922.1"
                     /translation="MSKPKYPFEKRLEVVNHYFTTDDGYRIISARFGVPRTQVRTWVA
                     LYEKHGEKGLIPKPKGVSADPELRIKVVKAVIEQHMSLNQAAAHFMLAGSGSVARWLK
                     VYEERGEAGLRALKIGTKRNIAISVDPEKAASALELSKDRRIEDLERQVRFLETRLMY
                     PKKAESLSSSHEKVKVLNELRQFYPLDELLRAAEIPRSTFYYHLKALSKPDKYADVKK
                     RISEIYHENRGRYGYRRVTLSLHREGKQINHKAVQRLMGTLSLKAAIKVKRYRSYRGE
                     VGQTAPNVLQRDFKATRPNEKWVTDVTEFAVNGRKLYLSPVIDLFNNEVISYSLSERP
                     VMNMVENMLDQAFKKLNPHEHPVLHSDQGWQYRMRRYQNILKEHGIKQSMSRKGNCLD
                     NAVVECFFGTLKSECFYLDEFSNISELKDAVTEYIEYYNSRRISLKLKGLTPIEYRNQ
                     TYMPRV"
     gene            1455..1607
                     /gene="hokA"
                     /locus_tag="IT892_003764"
     CDS             1455..1607
                     /gene="hokA"
                     /locus_tag="IT892_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokA"
                     /protein_id="HAP3136923.1"
                     /translation="MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFL
                     ACKLKE"
     gene            complement(1794..2006)
                     /gene="cspA"
                     /locus_tag="IT892_003765"
     CDS             complement(1794..2006)
                     /gene="cspA"
                     /locus_tag="IT892_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone/antiterminator CspA"
                     /protein_id="HAP3136924.1"
                     /translation="MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKS
                     LDEGQKVSFTIESGAKGPAAGNVTSL"
     gene            complement(2287..2577)
                     /locus_tag="IT892_003766"
     CDS             complement(2287..2577)
                     /locus_tag="IT892_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator"
                     /protein_id="HAP3136925.1"
                     /translation="MEYKDPMHELLSSLEQIVFKDETQKITLTHRTTSCTEIEQLRKG
                     TGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKLMRLIQANPALSKQLME"
     gene            3011..3721
                     /locus_tag="IT892_003767"
     CDS             3011..3721
                     /locus_tag="IT892_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3053 domain-containing protein"
                     /protein_id="HAP3136926.1"
                     /translation="MATGKSCSRWFAPLAALLMVVSLSGCFDKEGDQRKAFIDFLQNT
                     VMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQ
                     DYVTQSGPLREMNGSLGVLAQQLQNAKLQADAAHSALKQSDDLKPVFDQAFTKVVTTP
                     ADALQPLIPAAQTFTQQLVMVGDYIAQQGTQVSFVANGIQFPTSQQASEYNKLIAPLP
                     AQHQAFNQAWTTAVTATQ"
     gene            complement(3771..4745)
                     /gene="ghrB"
                     /locus_tag="IT892_003768"
     CDS             complement(3771..4745)
                     /gene="ghrB"
                     /locus_tag="IT892_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418009.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /protein_id="HAP3136927.1"
                     /translation="MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFA
                     EAEGLLGSNENVNAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTET
                     VADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMAL
                     AQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLF
                     GAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLS
                     MANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD"
     gene            complement(4849..5508)
                     /locus_tag="IT892_003769"
     CDS             complement(4849..5508)
                     /locus_tag="IT892_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family lipoprotein"
                     /protein_id="HAP3136928.1"
                     /translation="MKKRVYLIAAVVSGALAVSGCTTNPYTGEREAGKSAIGAGLGSL
                     VGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYYMDVQEAKLRDKMRGTGVSVTRS
                     GDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVIGYTDSTGGHDL
                     NMRLSQQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGKAQNRRVEITLSP
                     L"
     gene            5661..7994
                     /locus_tag="IT892_003770"
     CDS             5661..7994
                     /locus_tag="IT892_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418007.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin guanine dinucleotide-containing
                     S/N-oxide reductase"
                     /protein_id="HAP3136929.1"
                     /translation="MANSSSRYSVLTAAHWGPMLVETDGETVFSSRGALATGMENSLQ
                     SAVRDQVHSNTRVRFPMVRKGFLASPENPQGIRGQDEFVRVSWDEALDLIHQQHKRIR
                     EAYGPASIFAGSYGWRSNGVLHKASTLLQRYMALAGGYTGHLGDYSTGAAQAIMPYVV
                     GGSEVYQQQTSWPLVLEHSDVVVLWSANPLNTLKIAWNASDEQGLSYFSALRDSGKKL
                     ICIDPMRSETVDFFGDKMEWVAPHMGTDVALMLGIAHTLVENGWHDEAFLARCTTGYA
                     VFASYLLGESDGIAKTAEWAAEICGVGAAKIRELAAIFHQNTTMLMAGWGMQRQQFGE
                     QKHWMIVTLAAMLGQIGTPGGGFGLSYHFANGGNPTRRSAVLSSMQGSLPGGCDAVDK
                     IPVARIVEALENPGGAYQHNGMNRHFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPEL
                     VVISECFWTAAAKHADIVLPATTSFERNDLTMTGDYSNQHLVPMKQVVPPRYEARNDF
                     DVFAELSERWEKGGYARFTEGKSELQWLETFYNVARQRGASQQVELPPFAEFWQANQL
                     IEMPENPDSERFIRFADFCRDPLAHPLKTASGKIEIFSQRIADYGYPDCPGHPMWLEP
                     DEWQGNAEPEQLQVLSAHPAHRLHSQLNYSSLRELYAVANREPVTIHPDDAQERGIQD
                     GDTVRLWNARGQILAGAVISEGIKPGVICIHEGAWPDLDLTADGICKNGAVNVLTKDL
                     PSSRLGNGCAGNTALAWLEKYNGPELTLTAFEPPASS"
     gene            complement(7963..8403)
                     /locus_tag="IT892_003771"
     CDS             complement(7963..8403)
                     /locus_tag="IT892_003771"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP3136930.1"
                     /translation="MIREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRDAY
                     LANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKAVRRGIGKALMQYVQQRHPHLML
                     EVYQKNQPAINFYQAQGFHIVDCAWQDETQLPTWIMSWPVVQTL"
     gene            complement(8400..8963)
                     /gene="tag"
                     /locus_tag="IT892_003772"
     CDS             complement(8400..8963)
                     /gene="tag"
                     /locus_tag="IT892_003772"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAP3136931.1"
                     /translation="MERCGWVSQDPLYIAYHDNEWGVPETDSKKLFEMICLEGQQAGL
                     SWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAY
                     LQMEQNGEPFVDFVWSFVNHQPQVTQATTLSEIPTSTSASDALSKALKKRGFKFVGTT
                     ICYSFMQACGLVNDHVVGCCCYPGNKP"
     gene            9121..9819
                     /locus_tag="IT892_003773"
     CDS             9121..9819
                     /locus_tag="IT892_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418004.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HAP3136932.1"
                     /translation="MIIKKSGGRWQLSLLASVVISAFFLNTAYAWQQEYIVDTQPGLS
                     TERYTWDSDHQPDYNDILSQRIQSSQRALGLEVNLAEETPVDVTSSMSMGWNFPLYEQ
                     VTTGPVAALHYDGTTTSMYNEFGDSTTTLTDPLWHASVSTLGWRVDSRLGDLRPWAQI
                     SYNQQFGENIWKAQSGLSRMTATNQNGNWLDVTVGADMLLNQNIAAYAALTQAENTTN
                     NSDYLYTMGVSARF"
     gene            10048..11256
                     /locus_tag="IT892_003774"
     CDS             10048..11256
                     /locus_tag="IT892_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136933.1"
                     /translation="MTPSNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLDAP
                     VSQVAFSFGLLSLGLAISSSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSDNLMML
                     WLSAGVLVGLADGAGYLLTLSNCVKWFPERKGLISAFAIGSYGLGSLGFKFIDTQLLE
                     TVGLEKTFVIWGAIALLMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMRKPQYWM
                     LAVMFLTACMSGLYVIGVAKDIAQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDK
                     IARIRVITIGQVISLVGMAALLFAPLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFG
                     LNNLAKNYGVIYLGFGIGSICGSIIASLFGGFYVTFYVIFALLILSLALSTTIRQPEQ
                     KMLREAHGSL"
     gene            11580..13271
                     /gene="eptB"
                     /locus_tag="IT892_003775"
     CDS             11580..13271
                     /gene="eptB"
                     /locus_tag="IT892_003775"
                     /EC_number="2.7.8.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418002.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid A phosphoethanolamine
                     7''-transferase"
                     /protein_id="HAP3136934.1"
                     /translation="MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWK
                     GISAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYG
                     IIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRS
                     LAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAW
                     ARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKL
                     AQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFSSDL
                     YAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLI
                     ILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVID
                     QVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPANAQ
                     AFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQAKEAAAN"
     gene            13363..13439
                     /locus_tag="IT892_003776"
     tRNA            13363..13439
                     /locus_tag="IT892_003776"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13397..13399,aa:Pro,seq:cgg)
BASE COUNT         3215 a         3293 c         3428 g         3617 t
ORIGIN      
        1 gacagttaaa cacgaggcat ataggtctga ttccgatatt caattggagt cagacctttt
       61 aatttcaggc taattcttct gctgttgtag tattcaatat attccgtaac agcatccttc
      121 agttcgctta tattactgaa ctcatcaaga taaaaacact ccgactttaa ggttccaaag
      181 aaacactcca ccacagcatt atccagacaa ttgccttttc tggacatgct ttgtttaata
      241 ccatgttctt taaggatatt ttgatatctt ctcatacgat actgccatcc ctggtcagag
      301 tgcagaacag gatgctcgtg aggattaagc tttttgaatg cctgatcgag catattctca
      361 accatgttca tcactggtct ttccgaaagg ctgtaagaaa taacttcgtt gttgaagaga
      421 tctattactg gagacaaata cagcttgcgc ccattgactg caaattcagt aacatcggta
      481 acccacttct cgtttggccg cgtagccttg aaatctcttt ggagaacatt aggggcggtt
      541 tgccctacct ctcctctgta agagcggtat cgcttgacct taatcgctgc tttaagtgag
      601 agggttccca tcaggcgctg aacagcttta tggttaatct gtttcccttc tcgatgaaga
      661 gacagcgtta ccctacggta tccgtatcgg cctctattct cgtgataaat ctcactaata
      721 cgctttttaa cgtccgcata cttgtcaggc ttgctgagag cctttagatg ataataaaac
      781 gtactgcgcg gtatctccgc agccctgaga agctcatcaa gaggataaaa ctgccttagc
      841 tcgttgagta ctttcacttt ttcgtgggat gagctaaggc tttcagcttt tttagataca
      901 taagccgcgt ttcaagaaat cgaacttgcc tttcaagatc ctcaatgcgt cggtcttttg
      961 acagctccaa tgctgatgcc gctttttctg gatcaactga tattgcaatg tttcttttgg
     1021 tgccaatctt gagcgcgcgt aaaccagctt ctccgcgctc ttcatagacc ttcagccacc
     1081 tggctacaga accactacca gcaagcataa agtgagcagc agcctgatta agggacatgt
     1141 gctgctcgat cacagctttc acgaccttaa tacgcaactc tggatcagca ctaacgcctt
     1201 taggtttggg aattaaacct ttttctccat gtttttcata gagggcaacc catgtcctga
     1261 cctgggttcg ggggacacca aaacgtgccg agatgatcct gtaaccatca tcagttgtga
     1321 agtagtgatt cacgacttca aggcgctttt caaaagggta ttttggcttt gacatattag
     1381 gggctattcc atttcatcgt ccaacaaaat gggtgcagta catactcgtt ggaaatcaac
     1441 acaggaggct gggaatgccg cagaaatata gattactttc tttaatagtg atttgtttca
     1501 cgcttttatt tttcacctgg atgataagag attcactgtg tgaattgcat attaaacagg
     1561 agagttatga gctggcggcg tttttagcct gcaaattgaa agagtaagag tcttcggcgg
     1621 gaaattattc ccgccttact tacggcgttg cgcattctca ttgcacccaa atttattctt
     1681 cacaaaaata ataatagatt ttattacgcg atcgattatt tatttcctga aaacaaataa
     1741 aaaaatcccc gccaaatggc agggatctta gattctgtgc ttttaagcag agattacagg
     1801 ctggttacgt taccagctgc cgggccttta gcgccgcttt cgatggtgaa ggacactttc
     1861 tgaccttcgt ccagagattt gtaaccatcg ttctggatag cagagaagtg tacgaacaca
     1921 tctttagagc catcgtcagg agtgatgaag ccgaagcctt tgtcagcgtt gaaccatttt
     1981 acgataccag tcattttacc ggacatagtg tattaccttt aataattaag tgtgcctttc
     2041 ggcgatatgg cgtgctttac agattttgaa gcgttaaagg aatgtgcact acgaggggta
     2101 tcaacgataa ctcttgaagg gacttgcctt actacactgc tttaatggtc tgtacgtcaa
     2161 accgttgatg tgcattaagc cacgcattgg cgggtgatgc aacaattatt tttcatattt
     2221 atgattaatc ggttggaaaa cggtcctgtc atcaggaccg taaacagcaa taaagtggat
     2281 aaaagtctat tccatcaact gcttacttaa tgccgggttg gcttgaatca aacgcatcaa
     2341 ttttagttcg gcacttgaag gcttcacgcg tctggattcc cattccttta ccatggcgac
     2401 tgatacgccc aaaacccggg cgaaatcatc gatttttaat cctgtccctt ttcgtaactg
     2461 ctcaatttcg gtacaggacg ttgttctgtg cgtcagggta attttctgcg tttcatcttt
     2521 aaaaacaatc tgttccaggc tgctcaacag ctcatgcatt ggatctttat attccattga
     2581 aaactcctca aatcacactg cgggatcgtg aattgcatcg aagctcatta agaatagtcg
     2641 ggaaaagcag acacagcggg gtgaagtcag ggcatgctct ggctatgatt cgattcagcc
     2701 tgtcatttag cgtgacttat agccacctaa cgatctgata aatgccgata tatctcttac
     2761 cactcctgtt ttgtaaagat ttcgaaaatc taaccttctg cgaaggcgta aatctctggc
     2821 tacaaaaaag gcaacggcac tatcattttt taacaatgaa acaacaaatt aaccttgttt
     2881 cattttctcc atgattttac caggaagatt acgtagaaag ggtatcctgc aagcctgtcc
     2941 tggactatcc ttgtcacgtc agacacgcgt gtgtcgttgt gcgctttttt tgggtgaaag
     3001 gagtaagaaa atggcgacag gaaagtcctg ctctcgctgg tttgcgcctc ttgcggcgtt
     3061 attaatggta gttagcctga gtgggtgttt tgataaagaa ggcgatcagc gtaaagcgtt
     3121 tatcgacttc ctgcagaata cagtgatgcg tagcggtgaa cgtctaccaa ccctgactgc
     3181 cgatcagaaa aaacagtttg gtccttttgt ctctgattac gcgattctgt atggttattc
     3241 tcagcaggtg aatcaggcga tggattccgg tctgcgcccg gttgtagaca gcgttaacgc
     3301 aattcgcgta ccgcaggatt acgttacgca aagcggtccg ctgcgtgaaa tgaacggttc
     3361 gctgggtgtg ctggcgcaac aactgcaaaa tgcgaagttg caggccgatg ctgcgcactc
     3421 tgcgctaaaa cagagcgatg atttgaaacc ggtctttgat caggcattca ccaaagtggt
     3481 aacgacgcca gctgatgcat tgcaaccgtt gattccggcg gcacaaactt tcacgcaaca
     3541 actggtgatg gttggagact acattgctca gcaaggtact caggtgagct ttgtcgcaaa
     3601 tggcatccag ttcccgactt cacagcaggc aagtgaatat aacaaactga ttgcgccatt
     3661 accggcacag catcaggcgt ttaatcaggc ctggactaca gcagttactg caacccaata
     3721 aagagtaaaa gcccgagcga ttatcgggct ttactctacg cagtcgcggc ttagtccgcg
     3781 acgtgcggat tcacacagtt cttctcaacc tttccttgta acgcatcaat caaattatcc
     3841 acggcacagg cggccatgcc ataacgcgtc tcatgggtgg cagatccaat atgcggtact
     3901 gcgacgacgt tggccattga gagcaacggc gaatctacgg acagtggctc ttgttcgaag
     3961 acatccagcc cggcagcgtg aatttcgcct ttctgcaatg ctgcgatcag tgcattttcg
     4021 tcaaccaccg ggccacgtcc ggcattaatg aaaatggcgg aggatttcat tttggcgaat
     4081 tgttctgcgc caaacagatg atgcgtctca tcagttaacg gcaggatcag gcaaacgaaa
     4141 tctgactctt gtaacagagt atccaaatcg cagtagcggg cgttgaagcg ttcttctgct
     4201 tctttatggt ggcggcgcgc gttatagagg atgggcatgt tgaagccaaa gtgcgcacgt
     4261 tgtgccagcg ccatgccgat ccgtcccatc ccgacaatgc ccagtgtttt atggtgaacg
     4321 tcagtgccgt accagtccgg gcctatgctc gcggtccatt cgcctgcttt tacccgttct
     4381 gctacctcca caacccgacg agcggtagac aacaccagcg ccatcagcgt atcggcgacg
     4441 gtttctgtta atacggttgg cgtgtgcatc agcagaattt ttcgggcggt aagcgcatcg
     4501 acatcaaaat tgtcatagcc gacggagatc gttgatgtgg cacgcagttt cggcattttt
     4561 tccagcaatg cggcatttac attctcgttt gaacccagta aaccttcagc ttcggcaaaa
     4621 attgctgcat tttgttcgac ggtttgtggg ctgaggtttg ccacctggtg aacggtgaaa
     4681 tgctcttgca ggcgttgcag taaatcatca ggtaaggctt tgtagaggat aacggacggc
     4741 ttcatgcttc tctccattca ctgataaggc gatcacctta gcctgaaata tgatgaagga
     4801 aaactgaaga atgccaggtg atttctgcat cacctggcat gaaagggatt acagcgggct
     4861 taaggtaatt tctacacggc ggttttgcgc cttaccttct gcggtgctgt tgctggcgat
     4921 tgggttagcc gggccaaggc cctgagtacg gatgcggctg gcgtccacgc cctgggtgat
     4981 caacgcgctg gcaacggaat ccgcacgttg ctgggagaga cgcatgttca ggtcgtgacc
     5041 acccgtgctg tcggtataac caatcacgtt aaccgccgtt ttcggatact ctttcagtac
     5101 cattgccacg ccggtcaggg tgttagcgcc cgccggtttc agggtcgcgc tgctgctgtc
     5161 gaaggtcaca ttgttcggca tattgaggat aatgttatcc ccgctgcggg ttacgctaac
     5221 accagtgccg cgcattttgt cgcgcagctt cgcttcctgc acatccatgt aataaccaac
     5281 gccgccgccc agagctgcgc ctgctgctgc gccaatcagc gcgcctttac cgcgatcttt
     5341 cttcgaagaa gagagcgcac caatacccgc gcccacgaga gagcccagac ctgcgccgat
     5401 agcagattta cctgcttcgc gttcgccggt gtaagggtta gttgtgcagc cagataccgc
     5461 cagagcgcca ctcactacgg cggcaataag ataaacacgt ttcttcattg ttaatcctta
     5521 ataacctttt tattctttgc cacgggttcc gtggcgggag attatgccgc gtgaacatga
     5581 agattattcc tgggaatact cggaaatttg taagtaatat ttaactgctc aatacatcta
     5641 acctttcagg agtcttcggt ttggccaact catcctcacg atattccgtt ctgactgccg
     5701 cccattgggg gcccatgctg gttgaaaccg acggcgaaac cgtgtttagc tcgcgtggcg
     5761 cgttagccac aggaatggaa aactccttgc agagcgcggt tcgcgaccag gttcacagca
     5821 atacgcgggt acgatttcca atggtgcgaa aaggctttct tgcgtcaccg gaaaacccgc
     5881 aaggcattcg tgggcaggat gaatttgttc gcgtgagttg ggatgaggcg ctggatctta
     5941 ttcaccaaca acataaacgc attcgtgagg cttatggtcc ggcatcgatt tttgctggtt
     6001 cctacggctg gcgttcaaac ggcgtgctgc ataaggcctc gacattatta caacgctata
     6061 tggcgctggc aggcggttat accgggcatc tgggggatta ttcgaccggc gcggcacagg
     6121 cgatcatgcc gtatgtcgtg ggtggtagtg aagtttatca acagcagacc agttggccgc
     6181 tggtgctgga acatagcgat gtcgtggtgc tgtggagtgc taacccactc aatacgctga
     6241 aaattgcgtg gaatgcatcc gatgagcagg ggctttctta cttttctgca ctgcgtgaca
     6301 gcgggaaaaa gctgatctgc attgatccaa tgcgatcgga aaccgtcgat ttctttggcg
     6361 ataaaatgga gtgggtggca ccgcacatgg gcaccgatgt tgcgctgatg ctggggatcg
     6421 cccatacgct ggtggaaaat ggttggcacg acgaagcgtt tctggcgcgt tgcaccacag
     6481 gttatgccgt cttcgcctct tatttgctgg gcgagagtga cggaatagcg aaaaccgccg
     6541 aatgggcagc agagatttgt ggtgttggcg cagcgaaaat ccgcgagctg gcggctattt
     6601 tccaccaaaa taccaccatg ctgatggcag gctggggaat gcagcgccaa cagtttggtg
     6661 agcaaaaaca ctggatgatc gtcacgctgg cagcaatgtt ggggcaaatc ggcacacccg
     6721 gcggcggttt tggtctttct taccattttg ccaatggtgg taaccccacg cggcgttctg
     6781 cggtgctctc ttccatgcag ggcagcttgc cgggtggctg cgatgcggtg gataaaatcc
     6841 ctgttgcccg cattgttgaa gcactggaaa accctggtgg cgcatatcaa cacaacggta
     6901 tgaaccgaca tttcccggat attcgtttta tctggtgggc gggcggtgcc aactttactc
     6961 atcatcagga taccaatcgc ctgatccgtg cctggcaaaa accggagctg gtggtgatct
     7021 ctgaatgctt ctggacggcg gcggcaaaac acgcggatat cgttctgcct gcgactacct
     7081 cttttgagcg taatgatctc accatgaccg gtgattacag taatcagcat ctggtgccga
     7141 tgaagcaagt ggtgccgcca cgctatgaag cgcgtaatga ttttgatgtt tttgccgagt
     7201 taagtgaacg ctgggagaag ggcggttatg cacgttttac ggaaggaaaa agtgagctgc
     7261 aatggctgga aacgttttat aacgttgccc gacagcgcgg ggcaagccag caggttgaat
     7321 tgccgccatt tgctgagttc tggcaagcca accagttaat tgagatgccg gaaaacccgg
     7381 acagcgagcg gtttattcgc ttcgctgatt tttgccgcga tccgctggcg catccgttaa
     7441 aaaccgccag cggcaagatt gaaatcttct cacagcgtat tgccgattac ggttacccgg
     7501 attgccctgg gcatccaatg tggctggagc cggacgaatg gcagggcaat gccgaaccag
     7561 aacagttgca ggtactttct gcccatccgg cgcaccgcct gcacagccag ctgaattaca
     7621 gttctctgcg cgaattgtac gcggtggcaa atcgtgagcc tgtcaccatt catcctgacg
     7681 atgcccagga gcgcggcata caagatggcg atactgttcg gttgtggaac gcacgcgggc
     7741 aaattcttgc cggagcggtc attagcgagg gaattaaacc tggcgtgatt tgcattcacg
     7801 aaggggcatg gccggatctg gatttaaccg ctgacggtat ttgtaaaaac ggcgcagtga
     7861 acgtgctgac caaagatctc cccagctcgc ggctggggaa tggctgtgcg ggtaatacgg
     7921 cgctggcatg gctggaaaaa tacaacggtc cggaactgac acttacagcg tttgaaccac
     7981 cggccagctc ataatccatg tgggtagttg ggtttcatcc tgccatgcgc aatcgacaat
     8041 gtgaaaaccc tgtgcctggt aaaaatttat cgccggttga tttttttgat aaacctccag
     8101 catcaggtgg ggatggcgct gctgcacata ctgcatcagc gccttaccaa taccgcgcct
     8161 gacggccttc ggtgcgacaa acatcgctgc cagaaatcgg ccttccataa tgctgacaaa
     8221 accgagaagc ttaccgtctt cttcccagac ccagttttgc gcgttggcaa gataggcatc
     8281 ccgcaccagc ggaatgcagt cacgccagta attcgctttt ataaagggat gcccccaggt
     8341 tgtactttcc agccacagtt cgaggatcgc ggggagttct gaacgttgcg cttcccgaat
     8401 catggtttat ttcccggata gcaacagcag ccaaccacat gatcattcac cagcccacat
     8461 gcctgcataa aggagtaaca gattgtggtg ccgacaaact taaaaccacg ttttttcagt
     8521 gccttagata gggcgtcgga ggcggacgta gatgtgggaa tttcgctcaa cgttgtggct
     8581 tgtgtcacct gtggctgatg atttacaaac gaccagacaa agtcgacaaa cggttcgccg
     8641 ttctgttcca tttgcaggta cgcccgcgca ttaccaataa ttgcctgaat tttccctcga
     8701 tggcggataa tcccggcgtc ctgtaccagt ctttcgacat cctcttcctg cattgctgcg
     8761 accttcaccg gatcgaactg atgaaagcag gcgcgatagt tttcgcgttt tttgaggacg
     8821 gtgatccacg ataatccagc ctgctgccct tcaaggcaga tcatttcgaa cagtttttta
     8881 ctgtcagttt caggcacgcc ccactcatta tcatggtagg caatataaag cgggtcctga
     8941 ctcacccagc cgcaacgttc catactttcc ctcgctatgt acccgatcgt aaaaatttca
     9001 gccgcttttc ttgacgcatc ggtgaaaaag tcaatattta atacagggct actatgcccg
     9061 atatccttca tacaatgaca ataatattgc cgaattcggc tcttccctgg agtcgtgtta
     9121 atgatcataa aaaaaagcgg tggtcgctgg cagctaagcc tgctggcgag cgtggtaatc
     9181 agtgcctttt ttctcaacac agcttacgcc tggcaacaag aatatatcgt tgatacgcaa
     9241 cccggacttt ccacagagcg ttacacctgg gatagtgatc atcaacctga ttacaacgat
     9301 attttgtcgc aacgtattca aagtagccaa agggcgctgg gactggaagt caatctggcg
     9361 gaagaaaccc ctgtggatgt gaccagcagt atgagtatgg gctggaattt tcctttatat
     9421 gaacaggtta caaccggccc ggtcgcggca ttacattacg atggcacaac cacctcgatg
     9481 tataacgagt ttggcgacag tactaccacg ctgaccgatc cgttatggca tgccagcgtg
     9541 agtaccttag gctggcgtgt tgactcccgg cttggcgatc tccgaccctg ggcgcaaatc
     9601 agctataacc agcaatttgg cgagaatatc tggaaggcgc aatcaggcct gagccggatg
     9661 acggcgacaa accagaacgg caactggctg gatgtcaccg taggcgctga tatgttgctc
     9721 aatcaaaata ttgccgccta tgccgcgcta actcaggcag aaaataccac taataatagc
     9781 gactatctgt atacgatggg ggttagcgcc agattttaac gtaacagtca caattgaaac
     9841 cattaaataa caatagttgt ggcgatagtg ggtgctaact taccaaataa taaatttggt
     9901 gaataattgt cgcgtcattc attcctgaac taaggcattt cattccgttc tgatggcatt
     9961 tcatgccgtt tttccccagg cataaagtgc acttcgttat ggttgtcggc agagattttt
    10021 cctttttatt actgcaggaa tactgccatg acaccttcaa attatcagcg tacccgctgg
    10081 ctgacactca tcggtactat cattacccag tttgcgctgg ggtcggttta tacctggagc
    10141 ctgtttaatg gcgcgctttc cgccaagctg gatgcgccgg taagccaggt cgctttctct
    10201 ttcggcttgt taagtctggg gctggcaatt tcgtcttctg ttgcgggcaa attacaggaa
    10261 cgttttggcg ttaaacgcgt caccatggct tccggcattt tgctgggatt aggcttcttc
    10321 ctgacagcgc attctgacaa cctgatgatg ctgtggttaa gcgccggtgt gctggtggga
    10381 ctggcagatg gcgcgggtta tctgctgacg ctctctaact gtgtgaagtg gttcccggag
    10441 cgtaaaggtc tgatctccgc gttcgctatc ggttcttatg gtctgggtag cctgggtttc
    10501 aaatttatcg acacgcagct gctggaaacg gtcggtctgg aaaaaacctt tgtgatttgg
    10561 ggagcgattg cgctgttgat gattgttttc ggcgcaacgt taatgaaaga cgcaccaaaa
    10621 caggaagtga aaaccagcaa tggtgtggtg gagaaagatt acacgctggc agagtcgatg
    10681 cgtaaaccgc agtactggat gttagcggta atgttcctga ccgcctgcat gagcggcctg
    10741 tacgtgattg gggtagcgaa agatatcgcc caaagtctgg cacaccttga tgtggtttcc
    10801 gcagccaatg cagtcactgt tatttccatc gccaaccttt caggtcgtct ggtgctgggt
    10861 attctgtctg acaaaatcgc ccgtatccgt gttattacca ttggtcaggt gatatcgctg
    10921 gtgggtatgg cggccctgct gtttgcacca ttgaatgcag tgacgttctt tgcagcgatt
    10981 gcctgcgtgg catttaactt tggcggcact attaccgtct ttccgtcact ggtcagtgag
    11041 ttctttggcc tcaataacct ggcgaaaaac tacggtgtga tttatctcgg tttcggtatc
    11101 ggtagcattt gtggttcgat tatcgcctca ctgtttggcg gcttctatgt gaccttctac
    11161 gtgattttcg ccctgctgat tctgtcattg gcgctttcta cgacgattcg tcagccagag
    11221 cagaaaatgt tgcgtgaggc gcatggctcc ctttaatgct cagccgcgag ctactgggct
    11281 tcagcttccg tgtgcatcaa acgcatcaac gaaatgtata aacaatgact cgtaaaattt
    11341 gggccaatta actggccctt tttactgctt tttgtaacgc taaagtctct tttcaaactt
    11401 gcatttttgt aaatttgtgc ttcatgcaca ctctttcccc acactttttc cctttgctgt
    11461 ggtctactta ttcgcgcgtg tagattttac ttatctgact acctccgcac tttttccctg
    11521 ccgggcctga aaagccacta agcagggtgt tatcacctgt ttgtccaggg tttgtttgca
    11581 tgagatacat caaatcgatt acacagcaga agctgagctt tttgcttgca atctatattg
    11641 gcctttttat gaatggcgcg gttttttacc gccgcttcgg cagctatgcg cacgatttta
    11701 ccgtctggaa aggcatttct gctgttgttg aactggccgc caccgtactg gtgaccttct
    11761 ttttactacg tcttctttcg ctgtttggcc gccgcagctg gcgtattctg gcatcgctgg
    11821 tggtgctctt ttccgcaggt gccagctatt acatgacctt ccttaatgtg gtcattggtt
    11881 atggcatcat cgcttccgtc atgaccaccg atatcgacct gtcaaaagaa gttgttggtc
    11941 tgaactttat tctctggtta atcgccgtta gtgcattgcc tcttatcctt atctggaata
    12001 accgctgtcg ctacaccttg ctccgacaac tgcgaacccc agggcagcgt attcgcagcc
    12061 tggcggtcgt cgtactggcg ggtattatgg tttgggcacc gattcgtttg ctggatatcc
    12121 agcagaagaa agtggagagg gcgaccggcg ttgatttgcc gagttatggc ggtgtcgtag
    12181 cgaactctta tctgccatca aactggcttt ctgcgttggg gctgtatgcc tgggcgcggg
    12241 tcgatgaatc ttccgataat aattcattgc ttaatccggc gaagaaattc acttatcagg
    12301 caccgcaaaa cgttgatgac acttatgtcg tgtttatcat cggtgaaacc acgcgttggg
    12361 accatatggg tattttcggc tatgagcgta ataccacgcc gaaactggcc caggagaaaa
    12421 atctggcggc gttccgtggt tactcctgtg ataccgcaac caaactctca ctgcgttgca
    12481 tgtttgtacg tcaggggggc gcggaagata atccgcagcg cacattaaaa gaacagaaca
    12541 ttttcgcggt tctgaagcag ttaggattca gttctgacct ctacgctatg cagagcgaaa
    12601 tgtggttcta cagcaacacg atggcggaca acattgctta tcgtgagcag attggtgcgg
    12661 agccacgtaa tcgtggcaag ccggtagatg atatgttgct ggtagacgaa atgcagcaat
    12721 cgctagggcg caacccggat ggtaagcatc tgatcattct gcataccaaa ggttcgcatt
    12781 ttaactacac ccagcgttat ccgcgtagct tcgcgcagtg gaagccggaa tgtattggtg
    12841 ttgatagcgg ctgtaccaaa gcgcagatga tcaactccta tgacaactcg gtgacctatg
    12901 tggatcactt tatctccagc gtgattgatc aggttcgcga taagaaagcg attgtgttct
    12961 acgcagctga ccacggtgag tcaattaatg aacgcgagca cctgcacggc acgccgcgtg
    13021 aactggcacc gccggagcag ttccgcgtac cgatgatggt ctggatgtca gataaatatc
    13081 tggaaaatcc ggccaatgcg caggcgtttg cgcagctgaa aaaagaagcc gacatgaaag
    13141 tgccacgccg tcacgtagag ctgtacgata ccatcatggg ttgtcttggc tatacttcac
    13201 cggatggtgg aattaacgaa aacaacaact ggtgtcacat cccgcaggca aaagaggcag
    13261 cggctaacta agcggcctgc tgactttctc gccgatcaaa aggcattttg ctattaaggg
    13321 attgacgagg gcgtatctgc gcagtaagat gcgccccgca ttcggtgatt ggcgcagcct
    13381 ggtagcgcac ttcgttcggg acgaaggggt cggaggttcg aatcctctat caccgaccaa
    13441 attcgaaaag cctgctcaac gagcaggctt ttttgcatct gcagctcatg aggatgagaa
    13501 cctccggggg cagggaggtt cgactcgagc gaagcgagag aacgttgcgc cag
//
LOCUS       DACAOP010000112        13160 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.112, whole genome shotgun sequence.
ACCESSION   DACAOP010000112 DACAOP010000000
VERSION     DACAOP010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13160
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.112"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            66..356
                     /locus_tag="IT892_003777"
     CDS             66..356
                     /locus_tag="IT892_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP3136935.1"
                     /translation="MKLKIVAVVVTGLLAANVAHAAEVYNKDGNKLDLYGKVTALRYF
                     TDDKRDDGDKTYARLGFKGETQINDQMIGFGHWEYDFKGYNDEANGSRGKNL"
     gene            380..1335
                     /locus_tag="IT892_003778"
                     /pseudo
     CDS             380..1335
                     /locus_tag="IT892_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518781.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
     gene            1374..1709
                     /locus_tag="IT892_003779"
     CDS             1374..1709
                     /locus_tag="IT892_003779"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136936.1"
                     /translation="MQLMLFNLFSPALKLNTGLAILSPGAFEVHSDGIDVDNELFHYP
                     IKKAYTPYNIHTYKTEEVVNQRNIKVKNMTLDEINNTYCNNDYYNQAIREEPIDLLDR
                     SFSSSSWPF"
     gene            2033..3421
                     /locus_tag="IT892_003780"
     CDS             2033..3421
                     /locus_tag="IT892_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NarK family nitrate/nitrite MFS transporter"
                     /protein_id="HAP3136937.1"
                     /translation="MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLL
                     LAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRW
                     TVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK
                     QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWV
                     PLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFV
                     MLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLF
                     LTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQA
                     HKEAVTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLT
                     WLVYGRRKFSQK"
     gene            3503..7243
                     /locus_tag="IT892_003781"
                     /pseudo
     CDS             3503..7243
                     /locus_tag="IT892_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415985.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
     gene            7240..8784
                     /gene="narH"
                     /locus_tag="IT892_003782"
     CDS             7240..8784
                     /gene="narH"
                     /locus_tag="IT892_003782"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HAP3136938.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNV
                     ETKPGIGYPKNWEDQEEWQGGWVRDVNGKIRPRLGNKMGVITKIFANPVVPQIDDYYE
                     PFTFDYEHLHSAPEGKHIPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
                     EAMQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDA
                     DRIEEAASTEREVDLYERQCEVFLDPHDPSVIEEALKQGIPQNVIDAAQRSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPKSEGVLPAIESLRIPVQYLAN
                     MLSAGDTGPVLRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVAQVEEMYRYLAIA
                     NYEDRFVIPTSHREMAGDAFAERNGCGFTFGDGCHGSDSKFNLFNSSRIDAINITEVR
                     DKAEGE"
     gene            8784..9479
                     /gene="narW"
                     /locus_tag="IT892_003783"
     CDS             8784..9479
                     /gene="narW"
                     /locus_tag="IT892_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HAP3136939.1"
                     /translation="MQILKVIGLLMEYPDELLWECKEDALALIRRDAPMLTDFTHNLL
                     NAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDRGQAMVDLLAEYEKVGLQLDCRE
                     LPDYLPLYLEYLSVLPDDQAKEGLLNVAPILALLGGRLKQREAPWYALFDALLQLAGS
                     SLSSDSVTKQVNSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDV
                     APQYVDISAGGGK"
     gene            9476..10156
                     /gene="narI"
                     /locus_tag="IT892_003784"
     CDS             9476..10156
                     /gene="narI"
                     /locus_tag="IT892_003784"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HAP3136940.1"
                     /translation="MIQYLNVFFYDIYPYICATVFFLGSWLRYDYGQYTWRASSSQML
                     DKRGMVIWSNLFHIGILGIFFGHLFGMLTPHWMYAWFLPVAAKQLMAMVLGGICGVLT
                     LIGGAGLLWRRLTNQRVRATSTTPDIIIMSILLIQCLLGLSTIPFSAQYPDGSEMMKL
                     VGWAQSIVTFRGGSSEMLNGVAFVFRLHLVLGMTIFLLFPFTRLVHVWSAPFEYFTRR
                     YQIVRSRR"
     gene            10235..11128
                     /locus_tag="IT892_003785"
     CDS             10235..11128
                     /locus_tag="IT892_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HAP3136941.1"
                     /translation="MKPQVYHVDAFTSQPFRGNSAGVVFPADNLSEAQMQLIARDLGH
                     SETAFLLHSDDSDVRIRYFTPTVEVPICGHATVAAHYVRAKVLGLGNCTIWQTSLAGK
                     HRVTIEKHNDDYRISLEQGTPGFEPPLEGETRAAIINALHLTEDDILPGLPIQVATTG
                     HSKVMIPLKPEVDIDALSPDLNALTAISKKIGCNGFFPFQIRPGKNETDGRMFSPAIG
                     IVEDPVTGNANGPMGAWLVHHNVLPHDGNVLRVKGHQGRALGRDGMIEVTVTIRDNQP
                     EKVTISGTAVILFHAEWAIEL"
     gene            complement(11224..12069)
                     /gene="nhoA"
                     /locus_tag="IT892_003786"
     CDS             complement(11224..12069)
                     /gene="nhoA"
                     /locus_tag="IT892_003786"
                     /EC_number="2.3.1.118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-hydroxyarylamine O-acetyltransferase"
                     /protein_id="HAP3136942.1"
                     /translation="MTPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVL
                     LPREIQLDNQSPEEKLVIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPAL
                     PPRTHRLLLVELEEEKWIADVGFGGQTLTAPIRLVSDLVQTTPHGEYRLLQEGDDWVL
                     QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPAGGKLTLT
                     NFHFTHYENGHAVEQRNLPDVASLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTH
                     PEAGK"
     gene            12242..12811
                     /locus_tag="IT892_003787"
     CDS             12242..12811
                     /locus_tag="IT892_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415979.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAP3136943.1"
                     /translation="MSRFIPIELHHASRLLNHGPTVLITSFDEQSQRRNIMAAAWSMP
                     VEFEPPRVAIVVDKSTWTRELIEHNGKFGIVIPGVAATNWTWAVGSVSGRDEDKFNCY
                     GIPVVRGPVFGLPLVEEKCLAWMECRLLPATSAQEEYDTLFGEVVSAAADARVFVEGR
                     WQFDDDKLNTLHHLGAGTFVTSGKRVTAG"
     gene            complement(12808..13041)
                     /gene="pptA"
                     /locus_tag="IT892_003788"
     CDS             complement(12808..13041)
                     /gene="pptA"
                     /locus_tag="IT892_003788"
                     /EC_number="5.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tautomerase PptA"
                     /protein_id="HAP3136944.1"
                     /translation="MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIAL
                     QQIQPESWQAIWDAEIAPQMEALIKKPGYSMNA"
BASE COUNT         3310 a         3304 c         3290 g         3256 t
ORIGIN      
        1 taaatgacgc cgtttaaaat tcgtttagaa aatacgttta acgataatta aaaggattct
       61 gttaaatgaa attaaaaata gttgcggtgg ttgtaactgg tttgttagct gcgaacgtag
      121 cacacgctgc cgaagtctat aacaaggatg gtaataaact cgacctttat ggcaaggtta
      181 ccgctctacg ttattttact gatgataagc gtgacgatgg tgataaaact tatgcccgtc
      241 tcggctttaa aggagaaacg caaatcaatg atcaaatgat tggttttggt cactgggaat
      301 atgattttaa aggctataac gatgaagcca acggctcgcg cggcaagaat ctctgattga
      361 gttaagtgcc catcacaata tgatcactga ccttatatta cacaatcatc ccaggatgaa
      421 aacaatcact ttaaacgaca accatattgc acatttaaac gccaaaaaca ctacaaaact
      481 ggaatattta aacttaagca ataacaattt actgccaacc aatgacattg atcaactaat
      541 atcatcaaaa catctttggc atgtattagt taacggcatc aacaatgatc cacttgcaca
      601 aatgcagtac tggactgcag taagaaatat aattgatgac actaatgaag tgaccattga
      661 tttatcagga cttaatttaa ccactcaacc accagggctg caaaacttca catctatcaa
      721 tcttgataat aaccaactca cacattttga tgcaaccaac tacgatagac tcgtaaagct
      781 aagtctgaat agtaatgctc ttgagtcaat aaattttcct caaggcagaa atgtaagtat
      841 tacacatata tctatgaata ataatgctct cagaaatatt gatatagata ggttttcatc
      901 agttacttat tttagtgcgg cacataatca actagagttt gtgcaattag aatcttgcga
      961 atggctgcaa tacctgaatc tcaccataat caattaactg atattgttgc aggtaataaa
     1021 aatgaactct tactgctgga tctatcccat aataaactaa caagtttaca caatgactta
     1081 tttcccaact tgaatacgtt acttattaac aacaatttgc tttctgaaat taaaatattc
     1141 tatagcaact tctgcaatgt tcagacatta aacgctgcta acaaccagtt gaaatatata
     1201 aatcttgatt tcctgactta tcttccatct atcaaaagtt taagactgga caataataaa
     1261 ataacccaca ttgatactaa taatacatcc gatattggaa ctttattccc cataataaaa
     1321 cagagcaaaa cttaaatttt ttaaatgttt ctgggaagaa caattgccct actatgcagc
     1381 tcatgttatt taatttgttt tccccagcac ttaagcttaa tactggcctg gcaattcttt
     1441 cgcctggtgc atttgaagtt cactctgacg gaatagatgt ggataacgaa ttgtttcact
     1501 atcctattaa aaaagcatat accccatata atatacacac ttacaagaca gaggaagttg
     1561 taaaccagag gaatataaaa gttaaaaaca tgaccttaga tgaaataaac aatacttact
     1621 gtaataacga ttattacaat caggcaataa gagaggaacc gatagacctt ctggacagat
     1681 cgttttcctc cagttcatgg cctttttagt gaataaatca tcactaattc tataagtgtc
     1741 tggtcttgtt gataatatag ttaatatgta accctttaga ttcacgatct gaagggttga
     1801 aacatgacat acgttcaaag attaaccccg tttgaaggtt agcttgttag ttacatttag
     1861 taacacatat ctggctactt aatccccatt ctgcccccgc ggttacgctt tcttatctat
     1921 tctttcaatc agcacttcac ccaattcatc cttaattcta ataactggct attgcgcctt
     1981 acctcgtgtt ttgtcttttt ttcattacca atgtgtgcat gtgaggaaca atatggcact
     2041 gcaaaatgag aaaaatagtc gttatctttt gcgcgactgg aaaccagaaa atccggcctt
     2101 ctgggaaaat aaaggaaaac atattgctcg aagaaatctc tggatatcag tcagttgtct
     2161 acttcttgcc ttctgtgtct ggatgctatt tagcgcagtt accgttaatc tcaataaaat
     2221 cggttttaat tttactaccg atcaactctt tttattaacc gcattaccct ccgtttctgg
     2281 cgcattattg cgtgttccct actcctttat ggtgcctata ttcggtggac gccgatggac
     2341 ggtttttagt actgcaatcc tgattattcc ttgcgtctgg ctcggaattg ccgtgcaaaa
     2401 tccgaatact ccttttggga tatttatcgt tatcgctttg ctatgcggtt ttgcaggtgc
     2461 aaactttgct tcgagcatgg gcaatatcag tttcttcttt ccaaaagcca aacaagggag
     2521 cgctcttggg attaatggcg gattaggaaa cttaggtgta agtgtaatgc agctggttgc
     2581 accgctggtc atttttgtac ctgtatttgc ctttctcggc gtcaatggcg taccgcaggc
     2641 cgacggttcg gtgatgtcgc tggcgaatgc cgcatggatt tgggtaccgc tactggcgat
     2701 tgccacgatc gccgcatggt cagggatgaa tgatatcgcc agttcacgcg cctcaattgc
     2761 cgaccagctc cctgtcttac aacgcctgca tctctggctg ctgagcctgc tttaccttgc
     2821 caccttcggt tcgtttatcg gtttttctgc gggttttgtc atgctggcaa aaacccagtt
     2881 cccggatgtg aatattctgc gcctggcgtt ctttggccca tttatcggtg ccatcgcgcg
     2941 gtcggttggt ggtgctattt ccgataagtt cggcggcgtg cgggtgacgt tgatcaactt
     3001 tatttttatg gcgattttca gtgccctgct gttccttacc ttaccgggca caggctccgg
     3061 taatttcatc gccttttacg ccgtatttat ggggctgttt ctgactgcgg gtctgggaag
     3121 tggttctact ttccagatga tcgccgtcat ctttcgccag ataaccattt atcgggtaaa
     3181 gatgaaaggc ggtagtgatg agcaagctca taaagaagcc gtcaccgaaa cggcggcggc
     3241 tctgggcttt atctcagcca ttggcgcagt gggcggcttt tttattccgc aggcgtttgg
     3301 catgtcgctc aatatgaccg gctctccggt cggcgcgatg aaagtgtttt taatcttcta
     3361 catcgtttgt gtgctgctga cctggctggt ttatggtcgg cggaagttca gccaaaaata
     3421 agagatcgat gcctgatgta caaccgtgtc gcatccgaca aggcatcaga tcccaattca
     3481 ttcctggagc aggagtcatg tcatgagtaa acttttggat cgctttcgct acttcaaaca
     3541 aaagggcgaa acctttgccg atggtcacgg acaggtgatg catagcaacc gcgactggga
     3601 ggacagctat cgccagcgtt ggcagttcga caaaatcgtg cgttccaccc acggtgttaa
     3661 ctgtacaggc tcctgtagct ggaaaatcta cgttaaaaat ggtctggtga cctgggaaat
     3721 ccaacagacc gactacccgc gcactcgccc tgacctgccc aatcatgaac ctcgcggctg
     3781 cccgcgtggc gcaagttact cctggtatct ttacagcgct aaccgcctga aatacccgct
     3841 cattcgtaaa cgactgattg aactgtggcg cgaagccctc aagcaacaca gcgatccggt
     3901 actggcgtgg gcatcgatta tgaacgatcc gcaaaagtgc ctgagctaca aacaagtgcg
     3961 tgggcgcggc gggtttatcc gctccaactg gcaggaacta aaccagctga ttgccgccgc
     4021 taacgtctgg accatcaaaa cctacggccc ggatcgcgtt gccggtttct cgccgatccc
     4081 ggcgatgtcg atggtttctt acgccgccgg aacgcgttat ctgtcgctgc ttggcggcac
     4141 ctgtttaagt ttctacgact ggtattgcga cctgccgccc gcctcgccga tgacctgggg
     4201 cgagcaaacc gacgtaccgg aatctgccga ctggtataac tccagctaca tcatcgcctg
     4261 ggggtctaac gtaccgcaga cacgtacgcc ggacgcccac ttctttaccg aagtacgcta
     4321 caaaggcact aaaaccatcg ccattacccc tgactactct gaagtggcca aattgtgcga
     4381 ccagtggctg gcaccgaaac aaggcactga tagcgccctg gcgatggcaa tgggccatgt
     4441 gattttaaaa gagtttcatc tcgataatcc cagcgactac tttatcaact actgccgccg
     4501 ctacagcgac atgccgatgc tggtaatgct ggagcctcgc gacgatggta gctacgttcc
     4561 cgggcgcatg atccgcgcat ctgacctggt ggatggactg ggcgaaagca acaatccgca
     4621 gtggaaaacc gtagcagtta ataccgcagg tgaattggta gtgccgaacg gttcgattgg
     4681 tttccgctgg ggagaaaaag gcaaatggaa tctggaatcc attgccgccg gtacggaaac
     4741 cgaattgtcg ttaaccctgc tcggtcaaca tgacgctgtt gcaggcgtgg ccttccccta
     4801 ctttggcggc attgaaaatc cgcattttcg cagcgtaaaa cacaatccgg tgctggtgcg
     4861 ccaattgccc gttaaaaacc tgacgttagt cgatggcaac acctgtccgg tggtcagcgt
     4921 ttatgatttg gtactggcga attacggcct cgatcgcggg ctggaagatg aaaacagtgc
     4981 gaaagattac gctgaaatca aaccgtacac cccagcctgg ggtgagcaaa ttaccggcgt
     5041 gccgcgccag tatattgaaa ccatcgcccg tgaatttgcc gataccgccc ataaaacgca
     5101 tgggcgctcg atgattatcc tcggcgcagg tgttaaccac tggtatcaca tggacatgaa
     5161 ctaccgcggg atgatcaata tgctgatctt ctgcggttgt gtcgggcaaa gcggtggcgg
     5221 ctgggcacac tatgtcggcc aggaaaaact gcgcccacaa accggctggt tgccactggc
     5281 ctttgcgctc gactggaacc gaccaccgcg ccaaatgaac agcacctcgt ttttctacaa
     5341 tcattccagc caatggcgct atgaaaaagt ctctgctcag gagttacttt caccgctcgc
     5401 cgatgccagt aagtacagcg gtcatctgat tgatttcaac gttcgcgccg aacgtatggg
     5461 ctggctacct tctgcgccgc agctggggcg taacccgctc gggattaaag ctgaagccga
     5521 caaggccgga ttatccccca cagaatttac cgcccaggcg ctgaaatcgg gcgatttacg
     5581 tatggcctgc gaacaaccag atagcagcag caatcatccg cgtaatttgt ttgtctggcg
     5641 ctctaacctg cttggctcct ccggcaaagg ccacgagtat atgcagaagt atctgctggg
     5701 gaccgaaagc gggattcagg gcgaggaact cggtgccagc gacgggatca aaccggaaga
     5761 agtcgagtgg caaactgcag cgattgaagg caagctcgac ctgctggtga cgctcgactt
     5821 ccgcatgtcc agtacctgcc tgttctccga tatcgttctg cccaccgcca cctggtacga
     5881 aaaagacgat atgaacacct cggatatgca tccgtttatt catccgcttt ctgcggcggt
     5941 cgatccggcg tgggaatcac gcagcgactg ggaaatctac aaaggtatcg ccaaagcatt
     6001 ttcgcaagtg tgcgtgggtc atcttggcaa agaaaccgac gtggtattac aacccctact
     6061 gcatgactct ccggcagagc tctcacagcc gtgtgaagtg ctcgactggc gcaaaggcga
     6121 atgcgatctg attccaggca aaaccgcgcc gaatattgtg gcggtggagc gcgactaccc
     6181 tgctacgtat gaacgcttta cctcgctcgg gccattgatg gacaaacttg gcaatggcgg
     6241 taaagggatt tcgtggaata cccaggatga aatcgatttc ctcggcaaac tcaattacac
     6301 caagcgtgat ggcccggcac aggggcgtcc gctgattgac accgccattg acgcttcaga
     6361 agtgattctg gcactggcac cggaaaccaa cggtcatgtt gcagtcaaag cgtggcaggc
     6421 gctgggcgag atcaccgggc gcgaacatac ccatctggcg ctgcacaaag aggacgagaa
     6481 gattcgcttt cgcgatattc aggcgcagcc gcgtaaaatt atctccagcc ccacctggtc
     6541 cggtctggaa agcgatcacg tctcctataa cgcgggatac accaacgttc atgagttaat
     6601 tccgtggcgc acgctgtcgg gacgccagta gctctatcag gatcatccgt ggatgcgtgc
     6661 ttttggtgaa agcctggtgg cttatcgccc gcctatcgac acccgtagcg tcagtgagat
     6721 gcgccagata ccgccaaacg gcttcccgga aaaagcactt aacttcctga cgccgcacca
     6781 gaaatggggc attcactcaa cctacagtga aaacctgcta atgctgacgc tctctcgcgg
     6841 tggaccgatt gtctggatca gcgaaacaga tgcccgagaa ctgaccattg tcgataacga
     6901 ctgggtggaa gtattcaacg ccaacggcgc gctgactgcc cgcgcggtgg tcagccaacg
     6961 tgtaccgccg ggcatgacca tgatgtatca cgcccaggaa cgcattatga atattcctgg
     7021 ttcggaagta actggcatgc gcggcggcat tcataactcg gttacccgcg tttgcccgaa
     7081 accaacgcat atgattggcg gttacgcgca gctggcctgg ggctttaact actacggcac
     7141 cgtcggatcg aaccgcgatg agttcatcat gatccgcaag atgaagaacg ttaactggct
     7201 ggatgatgaa ggtcgcgatc aggtacagga ggcgaaaaaa tgaaaatccg ttcacaagtc
     7261 ggcatggtgc ttaacctcga caaatgtatc ggctgccata cctgttcggt gacctgtaaa
     7321 aacgtctgga ccgggcgcga aggcatggag tacgcatggt ttaacaacgt cgaaaccaaa
     7381 ccgggcattg gttatccgaa aaactgggaa gatcaggaag agtggcaagg cggctgggtg
     7441 cgtgatgtga atggcaagat acgcccgcgt ctgggcaaca agatgggcgt aataaccaaa
     7501 atcttcgcca acccggtggt gccgcagatt gatgattact acgaaccttt caccttcgac
     7561 tacgaacatt tgcatagcgc accggaaggc aaacatattc ctactgctcg cccgcgttca
     7621 ctgattgacg gcaaacggat ggacaaagtg atctgggggc caaactggga agaactgctg
     7681 ggcggtgagt tcgaaaaacg tgcccgcgac cgcaacttcg aggccatgca aaaggagatg
     7741 tacgggcagt ttgaaaacac cttcatgatg tacctgccgc gcctgtgcga acactgcctc
     7801 aatcccagct gcgtggcgac ctgcccaagc ggcgctatct acaaacgcga agaagacggc
     7861 attgtgctga ttgatcagga taaatgccgt ggctggcgtt tgtgcataag cggttgtccg
     7921 tacaaaaaaa tctacttcaa ctggaaaagc ggcaagtcag aaaaatgcat cttctgttac
     7981 ccacgaattg agtccggtca accgaccgtg tgctcagaaa cctgcgtggg tcgcatccgg
     8041 tatctgggcg tgctgcttta cgacgccgac cgcatcgagg aagcggcgag caccgagcgc
     8101 gaagttgacc tctatgaacg ccagtgcgaa gtgttcctcg atccacacga tccctcagtg
     8161 atcgaggaag ccctgaaaca aggtattcca caaaatgtga ttgacgctgc ccagcgttcg
     8221 ccagtctaca aaatggcgat ggactggaaa ctggcactac cgttgcaccc tgaataccgc
     8281 accctgccga tggtctggta cgttcctccg ctgtcaccga ttcagtccta cgcagatgcg
     8341 ggcggtttgc cgaaaagcga aggcgtgctg cccgccatcg aaagcctgcg tattccggtg
     8401 caatatctcg ccaatatgtt gagtgccggc gataccggtc cggtactgcg ggcgctgaaa
     8461 cggatgatgg cgatgcgcca ctatatgcgt tcacaaaccg tggaaggcgt tactgatact
     8521 cgtgccatcg acgaagtagg cctgagcgtc gcccaggtcg aagagatgta tcgctatctc
     8581 gccattgcca actatgaaga tcgttttgtt atcccgacca gccatcggga aatggcgggc
     8641 gatgccttcg cagaacgcaa cggctgcggt tttacctttg gcgacggttg ccacggttcg
     8701 gacagtaaat tcaacctgtt caacagtagc cgtatcgatg ccatcaacat caccgaagtg
     8761 cgcgacaaag cggagggcga ataatgcaga tcctcaaagt gatcggcctg ttgatggagt
     8821 atccggacga gctgttgtgg gaatgcaagg aggacgcgct ggcgttgatc cgccgcgacg
     8881 cgccgatgct tacggatttc acccacaacc tgcttaacgc gccgctgctg gataaacagg
     8941 ccgaatggtg cgaagtgttt gaccgcgggc gcaccacgtc gctgctgctg ttcgaacatg
     9001 ttcatgccga gtcccgcgat cgcggccagg caatggtgga cctgctggcg gagtatgaaa
     9061 aggtcggcct gcagctggat tgtcgggaac tgcccgatta tctaccgctg tatctggagt
     9121 atttaagcgt actgcctgac gatcaggcga aagaaggatt gctcaatgtt gcgccgatcc
     9181 tcgccctgct tggcggtcgc ttaaaacaac gcgaggcacc gtggtacgcg ttgtttgatg
     9241 ctctgctgca actggcggga agctcccttt caagtgacag tgtcacaaaa caagtaaaca
     9301 gcgaagagcg cgatgacacc cgccaggcgc ttgatgcagt gtgggaagag gaacaggtga
     9361 agtttattga agataacgcc acggcgtgtg acagctcgcc gcttaatcaa tatcagcgac
     9421 gctttagcca ggatgtcgcg ccgcaatatg tcgacatcag tgcgggaggt gggaaatgat
     9481 tcagtatctg aacgtctttt tttacgatat ctacccgtac atttgtgcga cggtgttttt
     9541 cctcggcagc tggctgcgct acgactacgg gcagtacacc tggcgcgcct cctcaagtca
     9601 aatgctcgat aaacgcggga tggtgatatg gtcgaatctg ttccatatcg gcattttggg
     9661 gattttcttc gggcacttgt tcggcatgtt aacgccgcac tggatgtacg cgtggttttt
     9721 gccagtggca gcgaaacaac tcatggcgat ggtgctcggc ggtatttgcg gtgtgttgac
     9781 gttgattggc ggcgcaggac tgctgtggcg caggctgaca aatcagcgcg tgcgtgccac
     9841 ttccactacg ccggatatca tcatcatgag cattttgctg atccagtgtc tgttggggct
     9901 aagtaccata ccgttttcag cacagtatcc tgatggtagc gaaatgatga agctggtggg
     9961 ttgggcgcaa agcattgtca ctttccgtgg tggatcgtca gagatgctca acggcgtagc
    10021 gttcgtcttc cgcctgcatc tggtgttggg aatgaccatc ttcctgctct tcccgttcac
    10081 ccgactggtg catgtgtgga gcgcgccgtt tgagtacttt actcgtcgat atcaaattgt
    10141 gcgttcgcgg cgataatttc accctggccg gatagccctt cgctctccgg ccacttgcag
    10201 gctatgatag ttctccagtc acaggagaac gttaatgaaa ccgcaggtgt accacgtcga
    10261 tgcttttacc tcacaaccgt ttcgcggcaa ttctgccggt gttgttttcc ccgccgataa
    10321 tcttagcgaa gcgcaaatgc agcttatcgc ccgcgattta ggccattcgg aaactgcttt
    10381 tctgctgcac agcgacgaca gcgatgtgcg catccgctac tttacgccaa cggttgaagt
    10441 gccgatttgc ggtcacgcga cagtagctgc gcactatgta cgtgcgaagg tgttaggttt
    10501 aggaaattgc acgatctggc aaacatcgct ggcaggaaaa catcgcgtga ctatcgaaaa
    10561 gcacaacgat gattatcgta tttcgctgga acaaggtacg ccgggctttg agccaccgct
    10621 ggaaggtgaa acacgtgcgg cgattatcaa cgcgcttcat ctcactgagg acgatattct
    10681 gccaggcttg ccaattcagg tggcaacaac aggacactca aaagtgatga tcccactgaa
    10741 accggaagtg gatatcgacg ccctttcgcc tgaccttaat gcgctgaccg ctatcagcaa
    10801 aaagattggc tgcaatggtt tcttcccgtt ccagatccgc ccaggcaaaa acgaaaccga
    10861 tggtcgcatg ttctcgcctg cgattggtat tgtggaagat ccggtgactg gcaatgccaa
    10921 tggcccgatg ggtgcatggt tggtacatca caacgtattg ccccacgatg gcaacgtgtt
    10981 gcgtgttaaa ggccatcagg ggcgcgcatt ggggcgtgac ggtatgattg aagtgacggt
    11041 gacaattcgt gataaccaac cggaaaaagt caccatttca ggcacagcgg tgattttgtt
    11101 tcatgccgaa tgggcaattg aactctgaaa ccgttgtctg atgcgcttcg cctgtcaggt
    11161 ctacaaccgg gctaatgtat gccggataag gcgtttacgc cgcatccggc aacctgacat
    11221 aaattatttt cccgcctccg ggtgcgtatc aaacgccgcc atcaccagcg ctaactcatc
    11281 cacggtaaag ccatgtttcg catcatccac gcccagacca aactgttctt gcatcacagc
    11341 atataatgac gccacatccg gtagatttcg ctgctccacc gcgtgcccat tttcataatg
    11401 ggtaaaatga aaattggtca gtgtcagctt gccgccggcc ggcaaatggc ggcacatcag
    11461 caaatgatgg cgaaaatgcg actgcggcca gtgcgccgac cagaaattgc ccatcacata
    11521 atcgctttgt tgctgctcgc agagatcaaa acggtacatc gactgccaat gctgatgatg
    11581 attaaactgc aacacccaat catcaccctc ctgcaacaac cgatactctc cgtgtggcgt
    11641 ggtctgcacg agatcggaaa ctaaacgaat cggcgcggtt agcgtctgcc caccgaaacc
    11701 gacatcagca atccattttt cctcttccag ttccaccaac agcaaacgat gggtgcgcgg
    11761 cggtaatgct ggcggatttg ataacactac gcgccctaac aagctgcgaa cgttaaaccc
    11821 cagctcgcgt aacacccgct caaacacgcc attctgctca aaacagtaac cgccacgacg
    11881 ggctatcacc agtttctctt ccggcgattg attatcaagc tgtatttccc tcggcagcaa
    11941 aacgtcgagg ttttcaaacg gaatggtgca attgtgtttc aggtgcaatg cacgaagcgt
    12001 atcaatattg accgcagcag ctcccgacca gttaatacgg gcaaaatagt gattcagaat
    12061 gggcgtcatc aggcgtttcc cttagtggtt ttctcaactt ataacctgga atagacgccg
    12121 caccggctat tttgtgcgat cgcggacatg catcacgttc gcaaatcgcc aatcccgtta
    12181 atttcgttac ttattgcgtt acggactacg cttaaaaaaa ccttcttcgc gaggcgatac
    12241 catgagccga ttcatcccca tagaattaca ccatgccagc cgtctgttaa atcatggccc
    12301 aacggtcttg atcaccagtt tcgatgagca atcccagcgg cgtaacatta tggctgcagc
    12361 ctggtcaatg ccggtggagt ttgaacctcc acgcgtggcg attgtggtag ataaatcgac
    12421 atggaccagg gagttgattg aacataacgg taaatttggc atcgttatcc cgggcgttgc
    12481 agcaactaac tggacgtggg cggtgggaag tgtgtcgggg cgtgatgaag ataaatttaa
    12541 ttgctatggc attccggttg tgagaggccc ggtatttggt ttgcctctgg tcgaggaaaa
    12601 atgtctggcg tggatggagt gtcgattgct acctgcgact tctgcgcaag aagaatacga
    12661 cacgctgttt ggcgaagtag tatcagcagc ggcagacgca cgggtatttg tcgaaggccg
    12721 ctggcagttt gatgatgata agctcaatac gttgcatcat ttaggtgctg ggacgtttgt
    12781 taccagcggc aagcgtgtta cggcgggtta agcattcatg ctataaccag gtttctttat
    12841 caaagcctcc atttggggcg cgatttcggc atcccagata gcttgccaag attctggttg
    12901 aatctgctgt agagcaatgc ttatcgaact gtctttactg ttcagatgac gaataataac
    12961 gtcggtaata tctgcagcaa gtgctgcttt ttgttgttcg tccagttcac gcggaaaaca
    13021 tttaatgtcg atgtgcggca tgattacgct ccttttgaaa gatgtcagta aaattaacac
    13081 acattgtgaa tgtcatgtgt ccggtaaagc gtttatacga caataatgcc cagggcaaga
    13141 ttacgaaagc ccgctccccg
//
LOCUS       DACAOP010000113        13154 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.113, whole genome shotgun sequence.
ACCESSION   DACAOP010000113 DACAOP010000000
VERSION     DACAOP010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13154
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.113"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..644)
                     /gene="rstA"
                     /locus_tag="IT892_003789"
     CDS             complement(<1..644)
                     /gene="rstA"
                     /locus_tag="IT892_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RstA"
                     /protein_id="HAP3136945.1"
                     /translation="MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRE
                     NPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKT
                     TPPAVLLARLRLHLRQNEQATLTKGLQETSLTPYKALHFGTLTIDPINRVVTLANTEI
                     SLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLL"
     gene            773..1108
                     /locus_tag="IT892_003790"
     CDS             773..1108
                     /locus_tag="IT892_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlpM family protein"
                     /protein_id="HAP3136946.1"
                     /translation="MGLVIKAALGALVVLLIGVLAKTKNYYIAGLIPLFPTFALIAHY
                     IVASERGIEALRATIIFSMWSIIPYFVYLVSLWYFTGMMRLPAAFVGSVACWGISAWV
                     LIICWIKLH"
     gene            complement(1105..1827)
                     /gene="folM"
                     /locus_tag="IT892_003791"
     CDS             complement(1105..1827)
                     /gene="folM"
                     /locus_tag="IT892_003791"
                     /EC_number="1.5.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydromonapterin reductase"
                     /protein_id="HAP3136947.1"
                     /translation="MGKTQPLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAI
                     DGLINAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKPGAPLADVL
                     ACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALD
                     NMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVD
                     YLLTSCFVTGRSFPLDGGRHLR"
     gene            complement(1864..3246)
                     /locus_tag="IT892_003792"
     CDS             complement(1864..3246)
                     /locus_tag="IT892_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP3136948.1"
                     /translation="MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWG
                     ITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSY
                     LVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVAT
                     LAKLLPLGLFVVLAMMMFKLDTFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAV
                     VVSARARNKRDVGKATLLAVLSALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEM
                     MGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRIFARQNAQAAPSASL
                     WLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVG
                     ACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIA
                     SVPATWMLVG"
     gene            complement(3432..4376)
                     /locus_tag="IT892_003793"
     CDS             complement(3432..4376)
                     /locus_tag="IT892_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HAP3136949.1"
                     /translation="MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTG
                     RFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGNSGNWRVVADLYKADAEKAEETSNR
                     VINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDA
                     NQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEAAKKVEIPGVATTA
                     SPSSEVGRFFETQSSKGGRYTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTE
                     VSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK"
     gene            4900..6432
                     /gene="pntA"
                     /locus_tag="IT892_003794"
     CDS             4900..6432
                     /gene="pntA"
                     /locus_tag="IT892_003794"
                     /EC_number="1.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HAP3136950.1"
                     /translation="MRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLAS
                     FDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQNPELM
                     QKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA
                     GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE
                     EAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMK
                     AGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIGYTDLPGRLPTQSSQLYGTNLVNL
                     LKLLCKEKDGNITVDFDDVVIRGVTVIRAGEITWPAPPIQVSAQPQAAQKAAPEVKTE
                     EKCTCSPWRKYALMALAIILFGWMASVAPKEFLGHFTVFALACVVGYYVVWNVSHALH
                     TPLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFR
                     KN"
     gene            6443..7831
                     /gene="pntB"
                     /locus_tag="IT892_003795"
     CDS             6443..7831
                     /gene="pntB"
                     /locus_tag="IT892_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HAP3136951.1"
                     /translation="MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIA
                     LIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVG
                     FNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR
                     HKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVV
                     SMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFG
                     TDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLR
                     ARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGAND
                     TVNPAAQDDPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGD
                     AKASVDAILKAL"
     gene            complement(7856..8890)
                     /gene="tqsA"
                     /locus_tag="IT892_003796"
     CDS             complement(7856..8890)
                     /gene="tqsA"
                     /locus_tag="IT892_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2 transporter TqsA"
                     /protein_id="HAP3136952.1"
                     /translation="MAKPIITLNGLKIVIMLGMLVIILCGIRFAAEIIVPFILALFIA
                     VILNPLVQHMVRWRVPRVLAVSILMTIIVMAMVLLLAYLGSALNELTRTLPQYRNSIM
                     TPLQALEPLLQRVGIDVSVDQLAHYIDPNAAMTLLTNLLTQLSNAMSSIFLLLLTVLF
                     MLLEVPQLPGKFQQMMARPVEGMAAIQRAIDSVSHYLVLKTAISIITGLVAWAMLAAL
                     DVRFAFVWGLLAFALNYIPNIGSVLAAIPPIAQVLVFNGFYEALLVLAGYLLINLVFG
                     NILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIVKIALEQTAGGQSI
                     AVLLSDLNKE"
     gene            9302..9667
                     /gene="mdtJ"
                     /locus_tag="IT892_003797"
     CDS             9302..9667
                     /gene="mdtJ"
                     /locus_tag="IT892_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtJ"
                     /protein_id="HAP3136953.1"
                     /translation="MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLS
                     YIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLI
                     KSGTRKARKPELEVNHGAV"
     gene            9654..9983
                     /gene="mdtI"
                     /locus_tag="IT892_003798"
     CDS             9654..9983
                     /gene="mdtI"
                     /locus_tag="IT892_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtI"
                     /protein_id="HAP3136954.1"
                     /translation="MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAA
                     VLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAG
                     MIMVKLA"
     gene            complement(10022..10843)
                     /locus_tag="IT892_003799"
     CDS             complement(10022..10843)
                     /locus_tag="IT892_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HAP3136955.1"
                     /translation="MRTTIAVVLGAISLTSAFVFADKPDVARSANDEVSTLFFGHDDR
                     VPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLALTAGHCLLTPPKGKADKAVALRF
                     VSNKGLWRYEIHDIEGRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPSGITP
                     LPLFEGDKAALTAALKAAGRKVTQAGYPEDHLDTLYSHQNCEVTGWAQTSVMSHQCDT
                     LPGDSGSPLMLHTDDGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLDQLSQK"
     gene            complement(10943..11026)
                     /locus_tag="IT892_003800"
     CDS             complement(10943..11026)
                     /locus_tag="IT892_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3136956.1"
                     /translation="MVGRYRFEFILIILILCALIAARFYLS"
     gene            complement(11119..11454)
                     /locus_tag="IT892_003801"
     CDS             complement(11119..11454)
                     /locus_tag="IT892_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416114.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid shock protein"
                     /protein_id="HAP3136957.1"
                     /translation="MKKQIEGMTMKKVLALVVAAAMGLSSAAFAAETTTTPAPTATTT
                     KAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAKKHSHQQP
                     AKPAAQPAA"
     gene            complement(11851..13104)
                     /locus_tag="IT892_003802"
     CDS             complement(11851..13104)
                     /locus_tag="IT892_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3136958.1"
                     /translation="MSRTTTVDGAPASDTDKQSISQPNQFIKRGTPQFMRVTLALFSA
                     GLATFALLYCVQPILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKP
                     VMVTALLLASICTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
                     SMGLYISGNSIGGMSGRLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHFR
                     PTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAV
                     VGLLSLAYLTGTWSSPKAGTMTTRYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGML
                     LFSAGFFAAHSVASSWIGPRAKRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNG
                     VGAFIALMLVIALLVGTRLHRRLHA"
BASE COUNT         3339 a         3195 c         3380 g         3240 t
ORIGIN      
        1 tcgagcagtt tttttcttaa ccgcgaaata gccacgtcca cgctacgatc cagtccgtca
       61 taactgacgc cgcgtaaatt tttcagcaat gcatcgcggt ccatgatttg cccggcatgg
      121 gtagctaatt cccacaataa ttcgaaatca gctgtcgaga gcgagatttc agtgttagcc
      181 agggtgacta cgcggttgat gggatcgatg gtcaacgtgc cgaaatgcag ggctttgtag
      241 ggagtcagag acgtttcctg aagacctttg gtcagtgtgg cttgctcatt ctgacgcaaa
      301 tgcaaacgta aacgcgctag caaaacagca gggggcgtcg ttttgagaat atagtcgcag
      361 gcacccattt ccagtgccag gatgtggttc atatcgctat cgagagaggt tagaagaaca
      421 atcggtccag accactttgc gcgtaaatca cgacaaatgg tcatgccgtc cttgcctggt
      481 agcatgatgt cgagtaacac caaatccgga ttttctcgca aaatggtttc ttcggcctgg
      541 tcgccgcgcg gctctacggt aacctgcata tcatgttttg ccaggtacgc ggcaatcagt
      601 gaaccgactt ccgcatcatc ttccacaaat acgatagtgt tcataacatt cacggtagat
      661 ataaaaacgt cacaatacac cgcgctgttt ttacttacta tcaatcgttt ctaaacaagt
      721 tttcatcagg tattctactg atgacttgtt atggaagtgt taaggtaaaa agatggggct
      781 ggtaatcaaa gccgcgctcg gtgcgctggt agtgctgttg attggtgttt tagcaaaaac
      841 gaaaaattat tatatcgccg ggctgattcc acttttcccg acctttgcgc ttatcgcgca
      901 ttatattgtt gccagcgaac gcggcattga agccttacgc gcaaccatca tttttagtat
      961 gtggtcgatt attccctatt ttgtttacct ggtgtcgctg tggtatttca ccggaatgat
     1021 gcgcttgccc gccgcttttg ttggttctgt tgcgtgttgg gggataagcg catgggtgtt
     1081 gattatatgc tggataaagc tgcattaacg cagatgacga ccgccatcaa gtgggaaact
     1141 gcgtccggtg acaaagcaac tggtaagtaa gtaatcgacc aggtcgatca cttctttctc
     1201 gccaggcgcg gttttcatca gtgatttatt cagcgcctgt tgtcgatatt cggcatcatc
     1261 atgttcatta aacaggatca gcgatggcgc aatagaattc actttcactt ccggtgccag
     1321 cttgcgggca aacgagcggg tcatattatc cagtgccgct ttgcttgcag catacgcaat
     1381 atgtttgtcg ctaccgcgct ccaccacata atcggtaaag tgaatgatat cgctggcggc
     1441 gtgtccgtgc ccacgcagta atctttccag cgcatggttg agcaggtatg gggtattaac
     1501 gtggatctgc atcatgcaag ccagtacgtc ggccagtggc gcacccggtt tttccgccat
     1561 ccacgcactg gcgttatgca aaatagcacg cagaccatgg gtgcttttta gtacttcatc
     1621 ggcaaacgcc atcacaccgt cgttggtcga aaaatcagcc tgaatacact gcgcacctgc
     1681 attaatcagt ccatcaatgg ctggatagtg tgtccgatag ctgacaatca ccggttgctt
     1741 ttgattaatg aaatgccatg cgagggcgag gccgatgcga cgacctccgc cagtaattaa
     1801 tattggcaag ggctgggttt tacccatcgt tatctccttt gctatccaac gatgggatga
     1861 acgttatccc accagcatcc aggtcgccgg aactgaggca attaacagca tgccaatcag
     1921 caccatttcc tgacggttca gtacattatc atgggtatgc gttttgcgcg cgtacaggaa
     1981 aaccagcagc cccggtgcat acagaacaac ggataacagc aagtgcattg gaccagaggc
     2041 gtacaataac cataagccat aaatgcaggc accgacacct accgctttat gcagtggacg
     2101 ggttgcgatt ttcagcaaga acgcgccgac caggaaatag ggcaccagaa tcatttctga
     2161 ggcgatggtc agcaacgtgt tgtaatcgga accggtcagc cagatgagta ccagacaaat
     2221 ttgcacgcag atgttggtca accacagtga ggcggatggc gcagcttgtg cgttctggcg
     2281 cgcaaaaatg cgcgggaatg ctttatgagt ggcggccagg aacggtactt ctgctgccat
     2341 gatggtccag cttaagtacg cgccgcaaac ggaaacgatc aaaccggcag cgatgatgat
     2401 ttcgccccat ggtcccatca tttccaccat cagaccggcc attgacgggt tacgaatttc
     2461 agccagttca ggacgtgcca ccacacccag cgaaagcagc gttaccagca agtaaacgcc
     2521 cagagcggag agaaccgcca gcagtgtcgc tttgccaaca tcacgtttat tacgcgcacg
     2581 cgcagaaaca accacggcac cttccacacc aatgaaaacc cacagggtga tcagcatggt
     2641 gtttttcacc tgttcccaaa cgggtacgcc aagtgcaagt ccggtgaagt cgagcttgaa
     2701 ggtatccagt ttgaacatca tcatcgccag cacaacaaac agacccagcg gcaacaattt
     2761 tgccagtgtc gccaccaggt taatgctggc agcggtttgc accccgcgca ggatcaaaaa
     2821 gtgaacaatc cacaataaag ccgatgcacc gactatcgat tgccaggtat taccatcgcc
     2881 aaacaggcgc aattccggcg tgtccgtaaa aaagcttaac gcggaaaaaa cgatcaccag
     2941 ataggagacg ttggcgatga ctgcgcacag ccagtatccc catgcggaac aaaagccgat
     3001 tagctcgcca aacccttcgc gggcataggt aaagataccg ccgtcaagtt cgggacgaat
     3061 gcgcgtgagg atcagcatgg caaaggccag caataaaatg ccagcgccag taatacccca
     3121 gccgatgagc agtgctgccg ggctggcaac tgccgccata ttttgcggca gactgaaaac
     3181 acccgcgccc agcattgagc ttaataccag cgcggtgagt gcgctcagtc ccagtttctt
     3241 ttccatcgat atccagtgat taaaacgtga taagaagaat aaatattagg gcaaaacgca
     3301 taaaaatgga gtttgccact gaagcgcggg attttacgaa gagatgtgtc tgcatgcaat
     3361 ggtcgcgggg aaatttgtga ctaaaaatgc gaaaggcggc atcaagccgc cttataggag
     3421 taactgaata gttatttata cagatctgcg ctgacggtca ggttattacc acgttcctgc
     3481 cactggcggg tgatgtggta atacttagca cctttcttcg cggcacgttt cgcaacctga
     3541 taggagactt cggtcatgtt gccgtagttg ccagagaatt tgatgctgtc gaacgggacc
     3601 atcatcgctg cggtcgcttt gttcagttct tcgactttag tgccatccgg gagcgtgacg
     3661 gtgtaacgcc cgccttttga tgactgggtt tcaaagaagc gaccgacttc agaacttggt
     3721 gatgcggtag tcgcaacacc cgggatctca actttcttcg cggcttcgcc accggcagcc
     3781 agagctgcac gtcctgcttc ggaatctgcc gggatcacat ccgggctctg gacgatacgt
     3841 ttcttagcat cttttttata gatgaatgca gtaatacgct ggttgccgcc ctggttggca
     3901 tcgatttgac gaacgatgta gaaagagtag gcacctttcg cttttgccgc tttggtgatg
     3961 gcatcattga cttctggctg gctacgatag aagccctgga cggtgaccgt gtcaaacggt
     4021 tcaatcagaa cagcctgatc tttcggcagt tcgacaacac cgttaattac gcgattactt
     4081 gtttcttctg ctttttcagc atcggcttta tagaggtcag cgaccacacg ccagttaccg
     4141 ctgttaccaa aatcagaagt gtcgacaaca taaaaagagg cggcaccttc tttatctgcg
     4201 cgacgagaaa cggctttcac cgcttcgcca atagcattaa aacgaccggt aaccactaca
     4261 cggtcaaaag gtttaaccgc tgccgcttgc tccggtgtca gttctgttgc tgcgttaacg
     4321 gagaatgccg tagcagaaag cagtgccgac gccaggaggg tgttcttaag cttcataaaa
     4381 ataatccttc gccttgcgca aaccaggtac tggtattgtt attaacgaga aacgtggctg
     4441 attattgcat ttaaacggtg taactgtctg cgtcattttt catatcacat tccttaagcc
     4501 aattttaatc ctgctcaaat gaccgtctat gcttaaaaaa cagccgtatc agcatcatta
     4561 ctactgaagc aactgaattg tataagttaa tttaatgtta agtagtgatt cgtgccgggg
     4621 cgatgtctcg ttttacccga ccgtcgaaga caattatcag tctttatccg gcgttctaag
     4681 gtgtttatcc cactatcacg gctgaatcgt taatattttg cgagttcacg ccgaaatact
     4741 gatttttggc gctagatcac aggcataatt ttcagtacgt tatagggcgt ttgttactaa
     4801 tttattttaa cggagtaaca tttagctcgt acatgagcag cttgtgtggc tcctgacaca
     4861 ggcaaaccat catcaataaa accgatggaa gggaatatca tgcgaattgg cataccaaga
     4921 gaacggttaa ccaatgaaac ccgtgttgca gcaacgccaa aaacagtgga acagctgctg
     4981 aaactgggtt ttaccgtcgc ggtagagagc ggcgcgggtc aactggcaag ttttgacgat
     5041 aaagcgtttg tgcaagcggg cgctgaaatt gtagaaggga atagcgtctg gcagtcagag
     5101 atcattctga aggtcaatgc gccgttagat gatgaaattg cgttactgaa tcctgggaca
     5161 acgctggtga gttttatctg gcctgcgcag aatccggaat taatgcaaaa acttgcggaa
     5221 cgtaacgtga ccgtgatggc gatggactct gtgccgcgta tctcacgcgc acaatcgctg
     5281 gacgcactaa gctcgatggc gaacatcgcc ggttatcgcg ccattgttga agcggcacat
     5341 gaatttgggc gcttctttac cgggcaaatt actgcggccg ggaaagtgcc accggcaaaa
     5401 gtgatggtga ttggtgcggg tgttgcaggt ctggccgcca ttggcgcagc aaacagtctc
     5461 ggcgcgattg tgcgtgcatt cgacacccgc ccggaagtga aagaacaagt tcaaagtatg
     5521 ggcgcggaat tcctcgagct ggattttaaa gaggaagctg gcagcggcga tggctatgcc
     5581 aaagtgatgt cggacgcgtt catcaaagcg gaaatggaac tctttgccgc ccaggcaaaa
     5641 gaggtcgata tcattgtcac caccgcgctt attccaggca aaccagcgcc gaagctaatt
     5701 acccgtgaaa tggttgactc catgaaggcg ggcagtgtga ttgtcgacct ggcagcccaa
     5761 aacggcggca actgtgaata caccgtgccg ggtgaaatct tcactacgga aaatggtgtc
     5821 aaagtgattg gttataccga tcttccgggc cgtctgccga cgcaatcctc acagctttac
     5881 ggcacaaacc tcgttaatct gctgaaactg ttgtgcaaag agaaagacgg caatatcact
     5941 gttgattttg atgatgtggt gattcgcggc gtgaccgtga tccgtgcggg cgaaattacc
     6001 tggccggcac cgccgattca ggtatcagct cagccgcagg cggcacaaaa agcggcaccg
     6061 gaagtgaaaa ctgaggaaaa atgtacctgc tcaccgtggc gtaaatacgc gttgatggcg
     6121 ctggcaatca ttctttttgg ctggatggca agcgttgcgc cgaaagaatt ccttgggcac
     6181 ttcaccgttt tcgcgctggc ctgcgttgtc ggttattacg tggtgtggaa tgtatcgcac
     6241 gcgctgcata caccgttgat gtcggtcacc aacgcgattt cagggattat tgttgtcgga
     6301 gcactgttgc agattggcca gggcggctgg gttagcttcc ttagttttat cgcggtgctt
     6361 atagccagca ttaatatttt cggtggcttc accgtgactc agcgcatgct gaaaatgttc
     6421 cgcaaaaatt aaggggtaac atatgtctgg aggattagtt acagctgcat acattgttgc
     6481 cgcgatcctg tttatcttca gtctggccgg tctttcgaaa catgaaacgt ctcgccaggg
     6541 taacaacttc ggtatcgccg ggatggcgat tgcgttaatc gcaaccattt ttggaccgga
     6601 tacgggtaat gttggctgga tcttgctggc gatggtcatt ggtggggcaa ttggtatccg
     6661 tctggcgaag aaagttgaaa tgaccgaaat gccagaactg gtggcgatcc tgcatagctt
     6721 cgtgggtctg gcggcagtgc tggttggctt taacagctat ctgcatcatg acgcgggaat
     6781 ggcaccgatt ctggtcaata ttcacctgac ggaagtgttc ctcggtatct tcatcggggc
     6841 ggtaacgttc acgggttcgg tggtggcgtt cggcaaactg tgtggcaaga tttcgtctaa
     6901 accattgatg ctgccaaacc gtcacaaaat gaacctggcg gctctggtcg tttccttcct
     6961 gctgctgatt gtatttgttc gcacggacag cgtcggcctg caagtgctgg cattgctgat
     7021 aatgaccgca attgcgctgg tattcggctg gcatttagtc gcctccatcg gtggtgcaga
     7081 tatgccagtg gtggtgtcga tgctgaactc gtactccggc tgggcggctg cggctgcggg
     7141 ctttatgctc agcaacgacc tgctgattgt gaccggtgcg ctggtcggtt cttcgggggc
     7201 tatcctttct tacattatgt gtaaggcgat gaaccgttcc tttatcagcg ttattgcggg
     7261 tggtttcggc accgacggct cttctactgg cgatgatcag gaagtgggtg agcaccgcga
     7321 aatcaccgca gaagagacag cggaactgct gaaaaactcc cattcagtga tcattactcc
     7381 ggggtacggc atggcagtcg cgcaggcgca atatcctgtc gctgaaatta ctgagaaatt
     7441 gcgcgctcgt ggtattaatg tgcgtttcgg tatccacccg gtcgcggggc gtttgcctgg
     7501 acatatgaac gtattgctgg ctgaagcaaa agtaccgtat gacatcgtgc tggaaatgga
     7561 cgagatcaat gatgactttg ctgataccga taccgtactg gtgattggtg ctaacgatac
     7621 ggttaacccg gcggcgcagg atgatccgaa gagtccgatt gctggtatgc ctgtgctgga
     7681 agtgtggaaa gcgcagaacg tgattgtctt taaacgttcg atgaacactg gctatgctgg
     7741 tgtgcaaaac ccgctgttct tcaaggaaaa cacccacatg ctgtttggtg acgccaaagc
     7801 cagcgtggat gcaatcctga aagctctgta accctgacgg cctctgctga ggccgtcact
     7861 ctttattgag atcgcttaac agaacggcga tgctttgacc tcccgctgtt tgttcaagcg
     7921 caattttgac aataattgtc aacggcacgg aaagcagcat acccaccggt cctaacaacc
     7981 atccccaaaa aatcaacgac aaaaatacca ccaatgtgga aagccccagc ccacgcccca
     8041 tgatacgcgg ctccagaata ttgccgaaga ccagattaat cagcagatat cccgccagca
     8101 ccagcaacgc ttcgtagaag ccattaaaca ccagtacctg agcgataggg gggattgccg
     8161 cgaggactga accaatattc gggatgtaat taagcgcaaa ggccagcaat ccccagacaa
     8221 aagcgaagcg aacatcgagt gcggcgagca tcgcccaggc gaccaggccg gtgatgatgc
     8281 tgatggctgt tttcagcacc agataatgag aaacactgtc aatcgcacgt tgaatcgccg
     8341 ccatcccttc aaccggacgc gccatcattt gctgaaattt tccgggcaat tgtggcactt
     8401 cgagcagcat aaacagcacc gtcagcagca ataaaaatat tgatgacatg gcattagata
     8461 actgcgtcaa taagttggtg agcaacgtca tcgccgcgtt cggatcaata taatgcgcca
     8521 gctggtcaac tgagacgtca atccctacgc gttgcaacaa cggttcaagc gcttgcagcg
     8581 gcgtcataat agagttgcga tattgcggta acgtccgcgt caactcgttg agcgcggaac
     8641 ccagataagc taatagcaac accatcgcca tcacgatgat ggtcatcaaa atcgacaccg
     8701 ccagtacacg cggcacacgc cagcggacca tgtgttgcac cagcgggtta agaataacag
     8761 caataaataa tgcgagaata aacggcacga tgatctcggc ggcaaaacgg ataccgcaga
     8821 gaataatgac cagcattccc aacataatga cgatttttag gccattgagc gtgatgatcg
     8881 gctttgccat gcttgtcccc gttttttctt cctttgctaa taataatgtc tttttcgctc
     8941 cgtcatcata acgaaaatca aaccgctcag gtaaagaagt gaaaatattt tgagttaatt
     9001 cttaagctat gatacaaatc aggcgtgttc aactaccgag gacaattatc atccgcgatg
     9061 acgagaagca acactgcgga taattgtaat attatggaca atttgttcag gacgttattt
     9121 tctacattta cccatcttcg tacctcatcc actatcttgc tcgtaggtga gcagcactgg
     9181 cgcaacgcgc tttagtcctt tcttctgcca aagcttgcgc tatgcgcggg gcttgaccac
     9241 tttactttgg tttcgctgaa ttaagcgaaa attaaaataa ttctcttgca ggagaaggac
     9301 aatgtatatt tattggattt tattaggtct ggctattgct acagaaatta ccggtacgct
     9361 gtcaatgaaa tgggcgagcg tcagtgaggg aaatggcggc tttattttaa tgctggtgat
     9421 gatttctctg tcgtatatat ttctctcttt cgccgttaaa aaaatcgcct taggcgtagc
     9481 ttatgcgctg tgggaaggta tcggtatttt atttattacc ttgtttagcg ttttgttatt
     9541 cgacgaaagt ttatcgctga tgaaaattgc cgggttaacc accctggtcg ccgggattgt
     9601 gttgataaaa tcaggtaccc gtaaagcgcg taaacctgaa ctggaggtga accatggcgc
     9661 agtttgaatg ggttcacgcc gcctggctgg cattggcaat cgtgctggaa atcgttgcta
     9721 acgtcttttt gaaattttct gacggctttc gtcgcaaaat atttggcttg ctctccctgg
     9781 cggcggtgct ggctgccttt agtgcgcttt ctcaagccgt taaagggatc gacttgtctg
     9841 tcgcttatgc attgtggggc gggtttggta ttgccgccac gttagccgca ggttggatct
     9901 tgtttggtca acggttaaat cgtaaaggct ggattggcct ggtcttgctg ttggctggaa
     9961 tgatcatggt gaaacttgcc tgatgaagac gctgcccgcg ctgtcgggca gcgtttgaac
    10021 attatttttg cgacagttga tccagcttgt cgcgaaaacc ggtaacagaa atggcccggt
    10081 tatcggcgcg ccagcgatct ttcgcggcag gagccgaact ttgcacccca attaattgcc
    10141 agccgtcatc ggtatgcaac atcagaggcg aaccgctgtc acccggcaag gtatcgcact
    10201 gatgtgacat caccgacgtt tgcgcccagc cagtcacttc acagttttga tgactgtaca
    10261 acgtatcgag atgatcttca gggtagcctg cctgagtcac tttacgacct gccgctttta
    10321 atgcggcggt aagcgcggct ttatctccct caaataacgg caacggcgta atgccagaag
    10381 ggggattacg tagcacaatc aatccgaagt cccacggcgc ggctgcggga ggtacaatcc
    10441 aaccatcccc atctgctttt aaccgctttc ccagtgtcgg atcaacgcgg ccttctatgt
    10501 cgtggatctc atagcgccaa agacctttat ttgacacaaa acgcagcgcc actgctttat
    10561 cggctttacc ctttggaggt gtcaataaac agtgtcctgc cgttaatgcc agattgggtg
    10621 caatcagcgt cgccgtacat aaattgccgc tggccgtttc cagttgccca accgcatccc
    10681 acggtgattg ggtcgtgtca ttcactggca cacgatcatc atgaccaaaa aacagggtgc
    10741 tgacctcatc gtttgccgat ctggcaacgt ctggtttatc tgcaaacaca aaagcagacg
    10801 tcaaactaat tgcacccaac actacagcaa tggttgtacg catatcacac tctggtgggt
    10861 aattatgatt attaaaagca aaccctcata aatactatag acgggacggg atgaaagtgg
    10921 gagtaaaatc agataactac aatcaggaaa gataaaaacg ggcggcaatc agtgcgcata
    10981 aaataaggat gatcagaatg aactcaaagc gataacggcc caccatacta ccctccgcta
    11041 aaggcggtgc taaacgttac ccgcttagca ccgtaatttt caggcgcgag ggggcgcgcc
    11101 agcattactg ttgaaaactt acgctgcggg ttgtgcagca ggttttgccg gttgctgatg
    11161 gctgtgtttc ttggcgtgtt tcttcgctgc ctgcgctttt tgttcagggg ctttctgttc
    11221 agctttcgta tttttatgat gctttttagc cgcctgcgct ttctgggcag gtgctgcttt
    11281 atgctgtttt ttatgatgtg tagttttcgc cggcgctgct ttggtggtcg tcgcagtcgg
    11341 agcaggtgtg gtcgtagtct ctgcagcaaa ggcggcagaa gacagaccca tagcagcggc
    11401 aacaaccaga gctaatactt ttttcattgt cataccctca atttgttttt tcatttaacc
    11461 ccactgcggg gccgttgaaa taactatatc cctgggaatg gcagacttcc gtgagtggtt
    11521 ggtttcagcg tgtaacgata tgtacaaacg ctgaataaat tacagcgttg ataataacgt
    11581 attgtgactt aagggaaatt tagctaccaa taatagtagt cttgatcggg ttaactattt
    11641 tactacttac aaagcagtag aataactgcg catcagtaat aaatgacaca cagcaaaatg
    11701 aatccgttta tttgggtact tataatcctg atgacgctag acgcgctgcg ggaattggct
    11761 ggcgcttcgt ctattttagg atggctatta acgttggttt gagctggcaa taagtccgga
    11821 cgggtattta ccgcagtccg gacttatttt tcaggcgtgc agacgacgat gcaaacgcgt
    11881 cccgaccagc agagcaatga ccagcatcag agcaataaat gcgccgacgc cgttccagcc
    11941 atagttatgc cagaaaacac cacccagcgt cccggcaata ctcgacccca gatagtaact
    12001 gaacagatac agcgaggagg cctggccttt agcgcgtttt gcgcgggggc cgatccagct
    12061 gctggctact gagtgggctg cgaagaatcc tgctgagaag agtaacattc cggcaaagat
    12121 cagccacagc gagctgaata aggtcatcag taaaccaaac agcataaccc ccgtcgaaaa
    12181 caacatcact ggaccacgcc catagcgggt ggtcatggtt ccggctttgg gtgagctcca
    12241 tgtaccggtc aaataagcca gcgataataa gccaaccacg gcctgactga catgccaggg
    12301 ggagagcatc aaccgatagc cgatgtaatt aaacagcgtg acgaacgacc ccatcagcaa
    12361 aaagccttct gcgaacaata acggtaatcc ccggtcacgc cagtgcagac gaaagttgat
    12421 aaacaacgtc ttagggcgca gcgaagtcgg gcgaaaatgg cgtgattcag ggaggatttt
    12481 ccagaacatc aacgccgagg ccagcgcgaa acaaccgatt gccgccagag caattcgcca
    12541 gttgaaaaag tccgtgaaga caccgctaat taagcgtccg ctcatgccgc caattgagtt
    12601 gccgctgata tacaacccca ttgaaaaggc cacgaaactg ggatggattt cctcgctaag
    12661 ataagtcatg ccaacagctg ccacgccact taacgaaagc ccaatcaagg cgcgcataat
    12721 caaaatgccg tgccagctgg tcatcattgt cgaaagtaac gtacaaatgg aggccaacag
    12781 tagcgccgtg accatcactg gtttgcgacc aatggcatcg gatagcgggc cagtaaacag
    12841 caaaccaata gccaacatcg ccgtggaaat ggacagtgaa atactactgt tcgcgggggt
    12901 taagccaaac tcctgcgaaa gcaccggaag gataggctgc acacaataga gaagtgcaaa
    12961 tgttgccagt ccggcagaga acagcgccag ggtgacgcgc ataaattgcg gcgtaccgcg
    13021 tttaataaat tgatttggct gagaaatgct ttgcttgtca gtgtcgcttg ccggagcgcc
    13081 atcaacagtt gtagtacggc tcacttgaaa tccttgctaa atatgcctgt agatcaggct
    13141 tatacatagg gtag
//
LOCUS       DACAOP010000114        13081 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.114, whole genome shotgun sequence.
ACCESSION   DACAOP010000114 DACAOP010000000
VERSION     DACAOP010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13081
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.114"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..394
                     /locus_tag="IT892_003803"
     CDS             <1..394
                     /locus_tag="IT892_003803"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308103.1"
                     /note="dehydratase component, catalyzes the isomerization
                     between 2-isopropylmalate and 3-isopropylmalate; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HAP3136959.1"
                     /translation="VAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSG
                     PVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGR
                     GGRTHLVSPAMAAAAAVTGHFADIRNIK"
     gene            405..1010
                     /gene="leuD"
                     /locus_tag="IT892_003804"
     CDS             405..1010
                     /gene="leuD"
                     /locus_tag="IT892_003804"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HAP3136960.1"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN"
     gene            complement(1059..2237)
                     /gene="setA"
                     /locus_tag="IT892_003805"
     CDS             complement(1059..2237)
                     /gene="setA"
                     /locus_tag="IT892_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetA"
                     /protein_id="HAP3136961.1"
                     /translation="MIWIMTMARRMNGVYAAFMLVAFMMGGAGALQAPTLSLFLSREV
                     GAQPFWIGLFYTVNAIAGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRH
                     YLTLITCGVLLASLANTAMPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPL
                     AFMLALNYGFTVMFSIAAGIFTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVR
                     MLFVASTLMWTCNTMYIIDMPLWISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVK
                     RYGKRRMMVIAVAAGVLFYTGLIFFNSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMP
                     GRAGAATTLFTNSISTGVILAGVIQGAIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
                     "
     gene            complement(2339..2470)
                     /gene="sgrT"
                     /locus_tag="IT892_003806"
     CDS             complement(2339..2470)
                     /gene="sgrT"
                     /locus_tag="IT892_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake inhibitor SgrT"
                     /protein_id="HAP3136962.1"
                     /translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEGLMQWDDRNSES"
     gene            2559..4214
                     /locus_tag="IT892_003807"
     CDS             2559..4214
                     /locus_tag="IT892_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SgrR"
                     /protein_id="HAP3136963.1"
                     /translation="MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     DIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     STNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEG
                     CYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHART
                     IKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLKIKEIDYDQWHTGEIES
                     DIWLNSANFTLPLDFSVFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
                     SKAMVPLLHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     regulatory      4248..4347
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4378..5361
                     /gene="thiB"
                     /locus_tag="IT892_003808"
     CDS             4378..5361
                     /gene="thiB"
                     /locus_tag="IT892_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /protein_id="HAP3136964.1"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVA
                     ADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRT
                     STPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     gene            5337..6947
                     /gene="thiP"
                     /locus_tag="IT892_003809"
     CDS             5337..6947
                     /gene="thiP"
                     /locus_tag="IT892_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease ThiP"
                     /protein_id="HAP3136965.1"
                     /translation="MATRRQPLIPGWLIPGVSATTLVVAVALAAFLALWWNAPQDDWV
                     AVWQDSYLWHVVRFSFWQAFLSALLSVIPAIFLARALYRRRFPGRLALLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLATLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMRSWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALLQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQVLEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFTVIEKLPGRNVKTD"
     gene            6931..7629
                     /gene="thiQ"
                     /locus_tag="IT892_003810"
     CDS             6931..7629
                     /gene="thiQ"
                     /locus_tag="IT892_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein
                     ThiQ"
                     /protein_id="HAP3136966.1"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGSLTIDGVDHTTMPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAVQQGKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELL
                     SGKASASALLGITG"
     gene            complement(7743..8507)
                     /locus_tag="IT892_003811"
     CDS             complement(7743..8507)
                     /locus_tag="IT892_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HAP3136967.1"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSFWHAWLAGIIGCLMGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
                     LAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGV"
     gene            complement(8593..9471)
                     /gene="araC"
                     /locus_tag="IT892_003812"
     CDS             complement(8593..9471)
                     /gene="araC"
                     /locus_tag="IT892_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon transcriptional regulator AraC"
                     /protein_id="HAP3136968.1"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRA
                     YWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCEEKVNDVAVKLS"
     gene            9810..11510
                     /gene="araB"
                     /locus_tag="IT892_003813"
     CDS             9810..11510
                     /gene="araB"
                     /locus_tag="IT892_003813"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HAP3136969.1"
                     /translation="MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
                     PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLGWPLEQLAAQHPELKTQINASQKQLLPALTEAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPCSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
                     "
     gene            11521..13023
                     /gene="araA"
                     /locus_tag="IT892_003814"
     CDS             11521..13023
                     /gene="araA"
                     /locus_tag="IT892_003814"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAP3136970.1"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGKKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
BASE COUNT         3069 a         3633 c         3479 g         2900 t
ORIGIN      
        1 agtggctatc gacaaagtgt ttatcggttc ctgtaccaac tcgcgcattg aagatttacg
       61 cgcggcagcg gagatcgcca aagggcgaaa agtcgcgcca ggcgtgcagg cactggtggt
      121 tcccggctct ggcccggtaa aagcccaggc ggaagcggaa ggtctggata aaatctttat
      181 tgaagccggt tttgaatggc gcttgcctgg ctgctcaatg tgtctggcga tgaacaacga
      241 ccgtctgaat ccgggcgaac gttgtgcctc caccagcaac cgtaactttg aaggccgcca
      301 ggggcgcggc gggcgcacgc atctggtcag cccggcaatg gctgccgctg ctgctgtgac
      361 cggacatttc gccgacattc gcaacattaa ataaggagca caccatggca gagaaattta
      421 tcaaacacac aggcctggtg gttccgctgg atgccgccaa tgtcgatacc gatgcaatca
      481 tcccgaaaca gtttttgcag aaagtgaccc gtacgggttt tggcgcgcat ctgtttaacg
      541 actggcgttt tctggatgaa aaaggccaac agccaaaccc ggacttcgtg ctgaacttcc
      601 cgcagtatca gggcgcttcc attttgctgg cacgagaaaa cttcggctgt ggctcttcgc
      661 gtgagcacgc gccctgggca ttgaccgact acggttttaa agtggtgatt gcgccgagtt
      721 ttgctgacat cttctacggc aatagcttta acaaccagct gctgccggtg aaattaagcg
      781 atgcagaagt ggacgaactg tttgcgctgg tgaaagctaa tccggggatc catttcgacg
      841 tggatctgga agcgcaagag gtgaaagcgg gagagaaaac ctatcgcttt accatcgatg
      901 ccttccgccg ccactgcatg atgaacggtc tggacagtat tgggcttacc ttgcagcacg
      961 acgacgccat tgccgcttat gaagcaaaac aacctgcgtt tatgaattaa tccccttgcc
     1021 cggtcaaatg accgggcttt ccgctatcgt ccacgtcatc aaacgtcttt aacctttgcg
     1081 gttaaaaata atgcgacaac agaaataacc gcaattaccc agtagacagc aaagtgcccc
     1141 caactttgtg caattgctcc ctgaataacg ccagccagaa ttaccccggt agaaatactg
     1201 ttagtaaata aggtggtagc tgcccccgct cttccaggca ttaaatcctg aaaccatagc
     1261 atcccaatac ccgcaacaat gccgataaat acagcgttaa aaagttgcag cgtcatcaac
     1321 gccatacggc tattaaagaa aatcaatccg gtgtaaaaca gtactcctgc cgccactgct
     1381 atgaccatca ttcgccgctt accataacgt ttgacatagt agccagccag aatcattgct
     1441 ggtatttcca gtccagctgc cgtccccatc aggaaacccg ccagtttgtc tggcaatcct
     1501 aactcgctac tgatccacaa cggcatatca ataatgtaca tggtgttgca ggtccacatt
     1561 aacgtcgagg cgacaaataa catccgtacg ttactatcct gccagccacc ttgcattgat
     1621 aaagcatttt ccgacggcag ttctacccgc gccacagacg gaagcataaa tgcaatcaat
     1681 accagactga gtgtgaatat cccggcggca atcgaaaaca tcaccgtaaa gccgtaattc
     1741 aacgccagca taaaggccaa cggtggaccg ataacccatg ccagagaaag ctgcgcacgc
     1801 atcaccgagc taaacatcac cacttctcgc gccgagttat ccgcatattc ccgcgccaga
     1861 gcaaataact gtggcattgc cgtattggcc agagatgcca gaagcacacc acaggtgata
     1921 agcgtcagat aatgacgatt aaatgcaaac aatagcgcat tgccgatagc catcaaacag
     1981 caaaatataa tcagttttcg ccgatcgccc tgactgtcag aacgttttgc caaccagagg
     2041 cttacgccga tcccagcaat agcattcacc gtataaaaga ggccgatcca gaaaggttgc
     2101 gcgccaacct cacgactcag aaataagctc aatgtaggag cctgtagcgc cccggccccc
     2161 cccatcataa aagcgaccag cataaatgcc gcgtaaacac cgttcatacg gcgagccatc
     2221 gtcattatcc agatcatacg ttcccttttt agcgcggcga gaataaaaaa aaccagcagg
     2281 tataatctgc tggcgggtga ttttacacca atactcagtc acacatgatg caggcaagtc
     2341 aactttcaga attgcggtca tcccactgca tcagtccttc aagcatggtt aatcgttgtg
     2401 ggacgcttaa ccaacgcaac cagcacaact tcgctgtcgc ggtaaaatag tgctgataaa
     2461 actgacgcat ggggcacccc cttgcttcat cgttaggaat tattgactta atatagggaa
     2521 aataaaattg ctgtcttttg cacaggagtt ccccttttat gccatctgct cgtctgcaac
     2581 aacagttcat ccgcctgtgg caatgctgcg agggtaaatc gcaggacaca acgctcaacg
     2641 aactggcagc gttattgagc tgctcgcgtc gtcatatgcg caccctgctc aacaccatgc
     2701 aggatcgcgg ctggctgacg tgggaagcgg aagtcgggcg cggtaaacgc tcgcgtctga
     2761 cattcctcta taccgggctg gcgcttcagc aacagcgggc ggaagacctg ctggagcagg
     2821 atcgtatcga tcaactggtg cagttggttg gcgacaaagc gactgtgcgg caaatgctgg
     2881 tttctcatct gggccgcagc ttccgccagg ggcggcacat cctgcgcgtg ctctactatc
     2941 gtccgttgcg taatctgcta cctggcagcg cattgcgccg ttccgaaacc catatcgccc
     3001 ggcaaatctt cagttcgcta acgcgcataa atgaggaaaa tggggaactg gaagcagaca
     3061 tcgcccacca ctggcagcaa atttcaccgc ttcactggcg tttctttttg cgtccaggag
     3121 tccattttca ccatggtcgt gaactggaaa tggacgatgt gatcgcctct ttaaaacgaa
     3181 tcaatacgct gccgctctat tcgcatattg ctgacattgt gtcgccgacg ccctggacgc
     3241 tggatatcca tctcacgcaa ccggaccgct ggttaccgtt actgctaggg caagttccgg
     3301 cgatgatcct gccgcgcgaa tgggaaaccc tcagtaactt tgccagccat cccatcggca
     3361 ccggtccgta tgcggtgatt cgcaacagca ccaatcaact gaaaattcag gcattcgatg
     3421 acttcttcgg ttaccgggca ttaatcgacg aagttaacgt ctgggttctg ccggaaattg
     3481 ccgacgagcc agccggaggg ctgatgctaa aaggtccaca gggcgaggaa aaagagattg
     3541 aaagccgcct ggaggaaggt tgctactatt tactgttcga cagccgcacc catcgcgggg
     3601 cgaatcagca agtcagggac tgggtaagct atgtgctttc tccaactaat ctggtctatt
     3661 tcgctgagga acagtaccag caactgtggt tcccggctta tggactgctc ccccgttggc
     3721 accatgcccg caccataaag agcgaaaaac cggctggcct ggaaagcctc accctaacct
     3781 tttatcagga tcacagtgag catcgggtga ttgccgggat catgcagcag attctggcaa
     3841 gtcaccaggt cacgctgaaa atcaaagaga tcgactacga tcagtggcat acaggagaga
     3901 tcgaaagtga tatctggcta aacagcgcca actttaccct gccgctggac ttctctgttt
     3961 tcgcacattt atgcgaagtg ccactgctac aacattgcat tcccattgac tggcaagccg
     4021 acgctgctcg ctggcgcaat ggcgagatga atctggcgaa ctggtgccag caactggtcg
     4081 ccagcaaagc gatggtgcca ttattgcacc actggctgat cattcagggg caacgcagta
     4141 tgcgcggcct gcgcatgaat accctcggct ggttcgattt taaatcagcg tggtttgcgc
     4201 caccggatcc atgattgctg gttgataaca aaatcactac actaacgccg ttctcaacgg
     4261 ggtgccacgc gtacgcgtgc gctgagaaaa tacccgtcga acctgatccg gataacgccg
     4321 gcgaagggat ttgaggctcc ttctcaagtc ctttgccact cttttttgag gtgcaaagtg
     4381 ttaaaaaaat gtctgcccct gctgttgctg tgcacagcgc ccgttttcgc taaacccgtt
     4441 ctgactgttt atacctacga ttccttcgcc gccgactggg ggcctggtcc ggtggttaaa
     4501 aaagcctttg aagccgactg taattgcgaa ctgaaactgg tggcgctgga agatggcgtt
     4561 tcgcttctca accgtctacg gatggaaggc aaaaacagta aagccgatgt ggtgctgggg
     4621 ctggataaca acctgttaga cgccgccagt aaaaccggac tgtttgccaa aagcggtgtg
     4681 gcagcggatg ccgttaacgt tcccggcggc tggaataatg acactttcgt accgtttgat
     4741 tatggctact tcgccttcgt ttatgacaag aacaaactga aaaacccgcc acaaagcctg
     4801 aaagaactgg ttgagagcga tcaaaactgg cgggtgattt atcaggatcc gcgcaccagt
     4861 acaccggggc tgggtctgtt gctatggatg caaaaagtct atggcgatga cgccccacaa
     4921 gcctggcaga aactggcgaa gaaaacggtc acggtcacca aaggctggag cgaagcctac
     4981 ggcctgtttt taaaaggtga aagcgatctg gtactgagtt acaccacctc tccggcttat
     5041 cacattctcg aagagaagaa agataactac gccgccgcga acttcagcga aggtcactat
     5101 ctgcaagtgg aagtcgccgc ccgcaccgct gccagcaagc agccggagct ggcgcaaaaa
     5161 ttcctccagt ttatggtttc tccggctttc cagaatgcga tcccaaccgg caactggatg
     5221 tatccggtgg caaacgtcac gctgcctgcc ggttttgaaa aattgaccaa acccgcaacc
     5281 acgttggagt tcacgccagc cgaagtggcg gcacaacgtc aggcatggat tagcgaatgg
     5341 caacgcgccg tcagccgtta attcccggct ggttaattcc aggtgtaagc gccaccacgc
     5401 tggtggtagc ggttgcgctg gcggcgtttc tcgccctgtg gtggaacgcg ccgcaggatg
     5461 actgggtggc agtctggcag gacagctatc tgtggcatgt ggtgcgcttc tccttctggc
     5521 aggcgtttct ctcggcactg ctctctgtca tacccgcgat attcctcgcc cgcgcgctct
     5581 atcgcaggcg ctttccgggt cggctggcgc tgttgcgtct gtgtgcaatg accttgatcc
     5641 tcccggtgtt ggtcgctgtt ttcggcattc ttagcgtcta tggtcgccag ggctggctgg
     5701 caacactctg ccaatcgctc ggtctggagt ggaccttttc gccctacggc ctgcaaggta
     5761 ttttgctggc ccatgtgttt tttaatctgc cgatggcgag ccgcttatta ctccaggcac
     5821 tggaaaacat ccccggcgaa cagcgtcaac ttgccgccca gcttgggatg cgtagctggc
     5881 attttttccg cttcgtcgaa tggccgtggt tacggcgaca aatcccgccg gttgctgcgc
     5941 ttatctttat gctctgtttc gccagcttcg ccaccgtgct atcgctgggg ggcggtccgc
     6001 aggcgaccac tatcgagctg gcaatctatc aggcgctgag ttacgactac gatcctgccc
     6061 gcgcggcaat gctggcgctg ctccagatgg tgtgctgcct cgggctggtg ctgttgagtc
     6121 agcgattgag taaggccatt gcgcccggca ccacgctgct gcaaggctgg cgcgacccgg
     6181 acgatcgtct gcatagccgc atttgcgaca cggtgttaat tgtgctggcg ctgctgctgt
     6241 tgctgccacc gttactggcg gtgatcgtcg atggggtaaa tcgccagttg ccggaagtgc
     6301 tggcacaacc ggtgctgtgg caggcgctgt ggacctcgtt gcgtattgcg ctggcggcag
     6361 gtgtattgtg cgtagtgctg accatgatgc tgctatggag cagtcgcgaa ctgcgggcgc
     6421 ggcagaaaat gctggcgggt caggtgctgg agatgagcgg catgttgatc ctcgccatgc
     6481 cggggattgt gctggctacc ggcttctttt tactgctcaa caacactatc ggcctgccac
     6541 aatctgctga cggcattgtg attttcacca atgcgttaat ggcgatccct tatgcgctga
     6601 aagtgctgga aaacccgatg cgcgatatca ccgcccgcta cagcatgtta tgtcagtcgc
     6661 tggggattga aggctggtca cgcttaaaag tggtggagct gcgcgccctg aaacgtccac
     6721 tggcgcaggc gctggccttt gcatgcgtgc tgtcgattgg tgattttggc gtggtggcgt
     6781 tgttcggtaa cgatgatttc cgcaccctgc cgttttatct ctaccagcaa attggctcct
     6841 atcgcagcca ggacggtgcg gtcaccgcgt taattctgct gctgctctgt tttctgctgt
     6901 ttaccgtgat tgaaaaacta ccggggcgaa atgttaaaac tgactgatat cacctggctt
     6961 taccaccatt tgccgatgcg ttttagctta acggtggaac gcggcgagca ggtggcgatc
     7021 ctcgggccaa gcggcgcggg taaaagtacc ctgctgaatt tgatcgccgg ttttctgacg
     7081 ccagccagcg gttcgctgac tatcgatggc gtagatcaca caactatgcc gccgtcacgc
     7141 cgtccggtgt cgatgctgtt tcaggagaac aacctgttca gccacctgac ggtcgcacag
     7201 aacatcgggc tggggctaaa tccgggattg aaactgaacg cggtacagca ggggaaaatg
     7261 cacgctatcg cccgccagat ggggattgat aatttaatgg cgcggttacc gggcgagctt
     7321 tccggcggtc agcgacagcg agtggcgtta gcgcgttgtc tggtacgcga acagccgatt
     7381 ttattgctcg atgaaccgtt ctctgcgctc gatccggcgt tacgtcagga gatgttgacg
     7441 ctggtgagca cgagctgcca gcagcaaaaa atgacgctat tgatggtgtc gcacagcgtg
     7501 gaagatgcgg cgcggatcgc cacgcgctcg gtagtagtcg ccgacgggcg catcgcctgg
     7561 cagggtatga ccaatgagtt gttgagcggt aaggcgagtg cttcggcact attggggatt
     7621 acgggttagt atgcactgtc ggatgcggcg tgaacgcctt atccgaccta cgggtagtgc
     7681 gttttgtagg cctgataaga cgcggcaagc gtcgcatcag gcaacccgca caagactatc
     7741 tcctaaaccc caaccacttt acgcaaaata tcgatataca ccggcatcaa cgggtggcga
     7801 attaacacca ccagcgccac cacgccgatg gcagaaatca acggcgtcag ccacaacaaa
     7861 cgaccgcggg acaaataatg actcaaacgg tcagtcgctt taccgctgcg ccataaccgc
     7921 cagcacagcc agccaccaac ccacaaaaac accgctgttg ccagcagcaa ccatttaaac
     7981 tcaccgctct gcattccggc aggaatatcg atcgccgcgc ccgccagaat ccctggcagg
     8041 aagtaaaacg gcggccacag caggcagccg ataatattcg gcgtaataaa tttagccacc
     8101 ggcagatcca gcattcccgc caccattggc accagcggac gcgtcgggcc aacaaaacga
     8161 ccgaccagaa tggtgaacat gctgtgttga tgcaacgcat gttcagtttt atcaagtagt
     8221 gctttgtttt tcttcagaaa tgaccagcga tgcaacggct ttttaaaacg ccaacccagc
     8281 cagaaagaaa tccagtcgcc catcaagcag ccaataatcc ctgccagcca ggcgtgccag
     8341 aaacttaact cgccgctgcc aatcagcgct cccagccccg ccatcagcac cgtaccgggt
     8401 agaatcaaac cgaccagcgc cagcgactcc agaaaggcca ccaacaccac cgccatcaat
     8461 gaatacacgg tggattgggt aataaagtgt tccagcaatg cttgcataat gtgcctgtca
     8521 aatggacgaa gcagggattc tgcaaaccct atgctactcc gtcaagccgt caattgtctg
     8581 attcgttacc aattatgaca acttgacggc tacatcattc actttttctt cacaaccggc
     8641 acgaaactcg ctcgggctgg ccccggtgca ttttttaaat actcgcgaga aatagagttg
     8701 atcgtcaaaa ccaacattgc gaccgacggt ggcgataggc atccgggtag tgctcaaaag
     8761 cagcttcgcc tgactaatgc gttggtcctc gcgccagctt aagacgctaa tccctaactg
     8821 ctggcggaaa agatgtgaca gacgcgacgg cgacaagcaa acatgctgtg cgacgctggc
     8881 gatatcaaaa ttgctgtctg ccaggtgatc gctgatgtac tgacaagcct cgcgtacccg
     8941 attatccatc ggtggatgga gcgactcgtt aatcgcttcc atgcgccgca gtaacaattg
     9001 ctcaagcaga tttatcgcca gcagctccga atagcgccct tccccttgcc cggcgttaat
     9061 gatttgccca aacaggtcgc tgaaatgcgg ctggtgcgct tcatccgggc gaaagaaacc
     9121 cgtattggca aatattgacg gccagttaag ccattcatgc cagtaggcgc gcggacgaaa
     9181 gtaaacccac tggtgatacc attcgcgagc ctccggatga cgaccgtagt gatgaatctc
     9241 tcctggcggg aacagcaaaa tatcacccgg tcggcagaca aattctcgtc cctgattttt
     9301 caccaccccc tgaccgcgaa tggtgagatt gagaatataa cctttcattc ccagcggtcg
     9361 gtcgataaaa aaatcgagat aaccgttggc ctcaatcggc gttaaacccg ccaccagatg
     9421 ggcgttaaac gagtatcccg gcagcagggg atcattttgc gcttcagcca tacttttcat
     9481 actcccacca ttcagagaag aaaccaattg tccatattgc atcagacatt gccgtcactg
     9541 cgtcttttac tggctcttct cgctaaccca accggtaacc ccgcttatta aaagcattct
     9601 gtaacaaagc gggaccaaag ccatgacaaa aacgcgtaac aaaagtgtct ataatcacgg
     9661 cagaaaagtc cacattgatt atttgcacgg cgtcacactt tgctatgcca tagcattttt
     9721 atccataaga ttagcggatc ctacctgacg ctttttatcg caactctcta ctgtttctcc
     9781 atacccgttt ttttggatgg agtgaaacga tggcgattgc aattggcctc gattttggca
     9841 gtgattctgt gcgagctttg gcggtggact gcgctaccgg tgaagagatc gccaccagcg
     9901 tagagtggta tccccgttgg cagaaagggc aattttgtga tgccccgaat aaccagttcc
     9961 gtcatcatcc gcgtgactac attgagtcaa tggaagcggc actgaaaacc gtgcttgcag
    10021 agcttagcgt cgaacagcgc gcagctgtgg tcgggattgg cgttgacagt accggctcga
    10081 cgcccgcacc gattgatgcc gacggaaacg tgctggcgct gcgcccggag tttgccgaaa
    10141 acccgaacgc gatgttcgta ttgtggaaag accacactgc ggttgaagaa gcggaagaga
    10201 ttacccgttt gtgccacgcg ccgggcaacg ttgactactc ccgctacatt ggtggtattt
    10261 attccagcga atggttctgg gcaaaaatcc tgcatgtgac tcgccaggac agcgccgtgg
    10321 cgcaatctgc cgcatcgtgg attgagctgt gcgactgggt gccagctctg ctttccggta
    10381 ccacccgccc gcaggatatt cgtcgcggac gttgcagcgc cgggcataaa tctctgtggc
    10441 acgaaagctg gggcggcctg ccgccagcca gtttctttga tgagctggac ccgatcctca
    10501 atcgccattt gccttccccg ctgttcactg acacttggac tgccgatatt ccggtgggca
    10561 ccttatgccc ggaatgggcg cagcgtctcg gcctgcctga aagcgtggtg atttccggcg
    10621 gcgcgtttga ctgccatatg ggcgcagttg gcgcaggcgc acagcctaac gcactggtaa
    10681 aagttatcgg tacttccacc tgcgacattc tgattgccga caaacagagc gttggcgagc
    10741 gggcagttaa aggtatttgc ggtcaggttg atggcagcgt ggtgcctgga tttatcggtc
    10801 tggaagcagg ccaatcggcg tttggtgata tctacgcctg gtttggtcgc gtactcggct
    10861 ggccgctgga acagcttgcc gcccagcatc cggaactgaa aacgcaaatc aacgccagcc
    10921 agaaacaact gcttccggcg ctgaccgaag catgggccaa aaatccgtct ctggatcacc
    10981 tgccggtggt gctcgactgg tttaacggcc gccgcacacc gaacgctaac caacgcctga
    11041 aaggggtgat taccgatctt aacctcgcta ccgacgctcc gctgctgttc ggcggtttga
    11101 ttgctgccac cgcctttggc gcacgcgcaa tcatggagtg ctttaccgat caggggatcg
    11161 ccgttaataa cgtgatggca ctgggcggca tcgcgcggaa aaaccaggtc attatgcagg
    11221 cctgctgcga cgtgctgaat cgcccgctgc aaattgttgc ctctgaccag tgctgtgcgc
    11281 tcggtgcggc gatttttgct gccgtcgccg cgaaagtgca cgcagacatc ccatcagctc
    11341 agcaaaaaat ggccagtgcg gtagagaaaa ccctgcaacc gtgcagcgag caggcacaac
    11401 gctttgaaca gctttatcgc cgctatcagc aatgggcgat gagcgccgaa caacactatc
    11461 ttccaacttc cgccccggca caggctgccc aggccgttgc gactctataa ggacacgata
    11521 atgacgattt ttgataatta tgaagtgtgg tttgtcattg gcagccagca tctgtatggc
    11581 ccggaaaccc tgcgtcaggt cacccaacat gccgagcacg tcgttaatgc gctgaatacg
    11641 gaagcgaaac tgccctgcaa actggtgttg aaaccgctgg gcaccacgcc ggatgaaatc
    11701 accgctattt gccgcgacgc gaattacgac gatcgttgcg ctggtctggt ggtgtggctg
    11761 cacaccttct ccccggccaa aatgtggatc aacggcctga ccatgctcaa caaaccgttg
    11821 ctgcaattcc acacccagtt caacgcggcg ctgccgtggg acagtatcga tatggacttt
    11881 atgaacctga accagactgc acatggcggt cgcgagttcg gcttcattgg cgcgcgtatg
    11941 cgtcagcaac atgccgtggt taccggtcac tggcaggata aacaagccca tgagcgtatc
    12001 ggctcctgga tgcgtcaggc ggtctctaaa caggataccc gtcatctgaa agtctgccga
    12061 tttggcgata acatgcgtga agtggcggtc accgatggcg ataaagttgc cgcacagatc
    12121 aagttcggtt tctccgtcaa tacctgggcg gttggcgatc tggtgcaggt ggtgaactcc
    12181 atcagcgacg gcgatgttaa cgcgctggtc gatgagtacg aaagctgcta caccatgacg
    12241 cctgccacac aaatccacgg caaaaaacga cagaacgtgc tggaagcggc gcgtattgag
    12301 ctggggatga agcgtttcct ggaacaaggt ggcttccacg cgttcaccac cacctttgaa
    12361 gatttgcacg gtctgaaaca gcttcctggt ctggccgtac agcgtctgat gcagcagggt
    12421 tacggctttg cgggcgaagg cgactggaaa actgccgccc tgcttcgcat catgaaggtg
    12481 atgtcaaccg gtctgcaggg cggcacctcc tttatggagg actacaccta tcacttcgag
    12541 aaaggtaatg acctggtgct cggctcccat atgctggaag tctgcccgtc gatcgccgca
    12601 gaagagaaac cgatcctcga cgttcagcat ctcggtattg gtggtaagga cgatcctgcc
    12661 cgcctgatct tcaataccca aaccggccca gcgattgtcg ccagcttgat tgatctcggc
    12721 gatcgttacc gtctactggt taactgcatc gacacggtga aaacaccgca ctccctgccg
    12781 aaactgccgg tggcgaatgc gctgtggaaa gcgcaaccgg atctgccaac tgcttccgaa
    12841 gcgtggatcc tcgctggtgg cgcgcaccat accgtcttca gccatgcact gaacctcaac
    12901 gatatgcgcc aattcgccga gatgcacgac attgaaatca cggtgattga taacgacaca
    12961 cgcctgccag cgtttaaaga cgcgctgcgc tggaacgaag tgtattacgg gtttcgtcgc
    13021 taagtagccg catccggtat gtaacgcctg atgcgacgct gacgcgtctt atctggccta
    13081 c
//
LOCUS       DACAOP010000115        12829 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.115, whole genome shotgun sequence.
ACCESSION   DACAOP010000115 DACAOP010000000
VERSION     DACAOP010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12829
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.115"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..783
                     /gene="wcaM"
                     /locus_tag="IT892_003815"
     CDS             <1..783
                     /gene="wcaM"
                     /locus_tag="IT892_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785186.1"
                     /note="WcaM from Salmonella enterica is essential for
                     biofilm formation on HEp-2 cells and chicken intestinal
                     tissue but not on a plastic surface; may be involved in
                     the biosynthesis of colanic acid; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein WcaM"
                     /protein_id="HAP3136971.1"
                     /translation="ILISDHVIERINCTNGNVNWGIGIGLAGSTYDNTYPDELAVKNF
                     VVANITGSDCRQLVHVENGKHFIIRNITARNITPDYSKKAGIDNATVAIYGCDNFVID
                     NINMENSAGMLIGYGVIKGRYLSIPQNFKLNNIHLDNTKREYKLRGIQISSGNATSFV
                     AITNVEMKRATLELHNQPQHLFLRNIRVMQQSATGPALKMHFDLRQDVRGKFMAKQDT
                     LLSLANVHAVNESGQSSVDIDRVNHQVVNVEAVNFRLPGRER"
     gene            948..1841
                     /gene="galF"
                     /locus_tag="IT892_003816"
     CDS             948..1841
                     /gene="galF"
                     /locus_tag="IT892_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GalU regulator GalF"
                     /protein_id="HAP3136972.1"
                     /translation="MINLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEIVLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQAQLLGLGHSILCARPIVGDNPFVVVLPDVVLDTASADPLRYNLAAMVARFNETGRS
                     QVLAKRMEGDLSEYSVIQTKEPLDNEGKVSRIVEFIEKPDQPQTLDSDLMAVGRYVLS
                     ADIWAELEHTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGPKFRKSIEKLLGE"
     gene            2286..3302
                     /gene="galE"
                     /locus_tag="IT892_003817"
     CDS             2286..3302
                     /gene="galE"
                     /locus_tag="IT892_003817"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000154261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAP3136973.1"
                     /translation="MTILVTGGAGYIGSHTVLQLIEGGYDVVVLDNLSNSSQESLHRV
                     GSLVSKKIPFIEADINDKQKLEEVFKNYDIDAVIHFAGLKSVGESVKKPLEYYINNVS
                     GTLTLLEVMKQASVYKFIFSSSATVYGNHSPVPNLEEYPIGNASCPYGTTKVMLEQVL
                     SDYAKSDDKLKIIALRYFNPTGAHPSGLIGEDPNGIPNNLVPYISQVAIGKLEKLSVY
                     GGDYETIDGTGVRDFIHVVDLASGHVSALRHIDKLQGYDVFNLGTGNGVSVLQVIDAF
                     EKASDKKVNYEIVARREGDIGSSWADVSKAERVLGWKAKYNIEDMMAHTWNWQKQNPN
                     GYGS"
     gene            3336..5552
                     /locus_tag="IT892_003818"
     CDS             3336..5552
                     /locus_tag="IT892_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP3136974.1"
                     /translation="MNLFFIVDKLDWAFGKIAQNIAKELSDFNVKIVCTDDFKTVADL
                     VLHLDKNVKEKSILHFFWRDYLMEVMNFTQRNPQYKEILISNIVTTHIPDHLFTYDDI
                     ANYERRIPLMNFVDGYFVTSAKLKELYSELSDFPPPHSVIYDNPEIPMSEGNSHDNSD
                     RKKLVWIGNSKWGEYLGYKDYKGLNKIVLPALDKLKKSGYTFDFIEFDSSKGKTEREV
                     ILKTLSDADILLISSECEGTPLPLLEAMANSCAIVSTDVGIANEVLPEKQRQYIVSRD
                     AEAFYDSLRNLLDDQRGLKELQRMNYLAYRQQFVDDGLIADKWALFFKDMCSKSQNEF
                     KNIFLREQKAPSLKERLISKTIYNLSRLALRLNLMNTLKQYSLLRKIYYKVAGTTTNQ
                     VDYDLLDEFYSNAIADKEVLAFYSAYWSGVATSTASFFKDDSIQYPYYSYEFPQVSNH
                     VYLNRLAEKLAASKTLKSVIMSGGTQLQMELAKKIKELNPKIKIFFAWHGSPAQWVDS
                     SQYSTFDGWYELYRERIVDGVISFKPELDEILNAYGIRAFSVSNYAVSGTSFSKKLAV
                     PDSGNFRVGLFAAMFSWYKNPFPQLLAIGSLKGCELVTNLHLENNMKWITSNIKLTAL
                     SENLNNKRFIELLSRLHVVCYVTNTECSPMIALESASVGTPCVVGPAGNIYKGFPELE
                     LYLVEKEVDNPTAIRNRLQLVRDNYAEVKVLLNAFVLEYNSRLELIKEKMYKELKQ"
     gene            5549..6328
                     /locus_tag="IT892_003819"
     CDS             5549..6328
                     /locus_tag="IT892_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3136975.1"
                     /translation="MKESLTDIYSSIKSWHLWTTLGWLELRQRYKRSIVGPFWITLSM
                     AVLIIALGVIYGELFKLEVKEYLPMLAVGLVFWNFISGVINEGCVTFISSSSFISQLP
                     TKKFIYIMQMLWRNFMMLCHNIVIVIGVLIIFNVFSLKNFPLFILGFMIVVVNLIWIA
                     TLFAVISVRFRDFPQMVMSFMQVVFYITPILFSGTMLAKYSLLLKLNPFAWFIEIIRS
                     PLVGKMPELYCYYNSIILACVGTVISLITFAKCRNRIAYWV"
     gene            6335..7087
                     /locus_tag="IT892_003820"
     CDS             6335..7087
                     /locus_tag="IT892_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000018742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O89/0101/0162 family O-antigen ABC transporter
                     ATP-binding protein Wzt"
                     /protein_id="HAP3136976.1"
                     /translation="MSHLIDLKDVGVEFPIYDAKSRSFKSQVANLTRGVISSKKESST
                     VTVKSLDGLTFSLKEGDKLGLIGNNGAGKSTLLKLLAGIYEPTSGTIKRKGKIVPLLD
                     IALGMDDDSTGYQNIKLRGLLLGMTNAEIESKIEEIACFTELGDYLNLPIRVYSTGMR
                     VRLAFAVSTSVDPDVLLLDEIIGTGDASFLNKAKKRFQELQERAKVVVLSSHDNNVIL
                     KTCNKVLWLEGGKPKMIGDPEEVLNKYMDSVV"
     gene            7153..8184
                     /locus_tag="IT892_003821"
     CDS             7153..8184
                     /locus_tag="IT892_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001581568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP3136977.1"
                     /translation="MQVVELLLELQKCGHSVRLISLTPPVDLIDKLISNDIPVVSLGM
                     KSKLALPMAAFKLAMLIRQNSPDIVHSHMFHANILVRFVRALLGRRSSIICTAHSVRE
                     GGSARDWLYRLTNKLSDLNTVVSDAARQRFINDKVFPPEKTLTVYNCINIDHFCIIDR
                     QGRKRFRWITVGRLVKIKNQLLILQAMMQLPHSELIIVGEGEERLTLQTFIDQNSLSE
                     RVTLLGKKDNVVDYYHDSDAFVLASDYEGFALVVAEAMACGLPVVATDCGGPAEIIGN
                     GQDFGITISVNDVHHLTAAMQQIESLDIEQRKGSGYRARERVIEKFSAKKIVSQWEDI
                     YLCIQKNRI"
     gene            8194..9348
                     /locus_tag="IT892_003822"
     CDS             8194..9348
                     /locus_tag="IT892_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP3136978.1"
                     /translation="MKIALIGTTAESLIQFRKELINLLHKNGHVVYAFAIDYDDVTKE
                     KVKSFGAIPVHYCFSRTGLNPFSDVINTYKLYKILKSLQLDLAFSYFSKPAIFGTLAA
                     KFARIQKRYAMLEGLGFFFTNSGGQVSLRTKLLKKILVSLYKVSFRHIESLILLNADD
                     KRDLLVNEKIQVKKVHILGGIGLNMSDYPYCPPPVEPVSFIFVARFLQEKGVYEFIEA
                     AKIVKKKFPETHFCMLGHLDLHNPGSLTIERLNDLKCNNIIELPGHVDNVQEWLAKAS
                     VFVLPSWREGFPRSTQEAMAMGRAVITSDVPGCRDTVVDGVNGFLIKPRSSHALAEKM
                     LCFLHQPELITQMGNASHQIALQQFDSSIVNSKLMKILRVDFENTKSNVC"
     gene            9396..10585
                     /locus_tag="IT892_003823"
                     /pseudo
     CDS             9396..10585
                     /locus_tag="IT892_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000440491.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            10589..12670
                     /locus_tag="IT892_003824"
     CDS             10589..12670
                     /locus_tag="IT892_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP3136979.1"
                     /translation="MSARLKLLPGLKSTEYVYSDLHALLDTNGGSSLGPNIGSDGSNL
                     TITCLSMSRVFLTEKLVNSIYQHIPYFKGDILIVDNGSTVEELSILQNLSDRIPLNIR
                     VVELGNNFGVSGGRNKTLEHIKTEWAMFLDNDIYFINNPLPRLQNDISRLGCHFINMP
                     LLDSDGETLFANGGNVFLDIDDDSVHVGAGSACIQEKTITYDGEGFLSTFLFGGASVI
                     KIATLKNLGKYDENMFIGFEDIDLSIRLYQSGMKVGTCGAISLIHDHPKPSSNKDKDY
                     EKIRFTRSILKESADYLENKWGMVFWSAPVDDWLEEKQRSFELTTQHNDNLSQFDDNK
                     KGATYDLSVSKPKIALIIDTENWAFSNIANQIVNYLSDSYDFTIIPTEIVDNISQVIM
                     MTRNYDITHFFWRESLRLIYDEYYINYNRTIGFDELSFKKEFLDGRIITSSVYDHLFL
                     DEQAIKLRKTFYNDLITAYTVSSSKLYDIYSSIVEYPKPSVLAEDGVNLKLFYPINLE
                     RFDNIESRALRVGWAGNSKWAGELEDFKGYHSLLKPAVEQLQSEGLNIELVLADRQLG
                     FIPHDEMVKYYSQIDVYVCPSKIEGTPNPVLESMACGVPVISTDVGVVKDAFGEMQKE
                     WILPVRSKDTLIDKLRDFYHKRNSVVKCLSSENLQQIKKWDWKVKSENFRTFFDKVLE
                     SKKHSEISNKM"
BASE COUNT         4026 a         2142 c         2736 g         3925 t
ORIGIN      
        1 atcctcattt ctgaccatgt cattgaacgt atcaactgta ccaacggcaa cgtgaactgg
       61 ggcatcggca tcggtctggc ggggagtacc tatgacaata cctatcccga tgaactggcg
      121 gtaaaaaact ttgtggtagc gaacatcacc ggtagcgact gccgacagtt agtccatgtg
      181 gagaacggca aacactttat tattcgtaat attaccgcgc gaaatatcac cccggattat
      241 agtaagaaag cgggcattga taatgcgacg gtcgctattt acggatgtga taatttcgta
      301 attgataata tcaatatgga gaatagcgca ggtatgctca ttggttacgg cgtaatcaaa
      361 gggcgttatt tatccattcc acaaaacttt aagttaaata atatccatct ggataatacg
      421 aaacgtgaat acaaattgcg cggtattcag atctcctctg gtaatgcgac atcatttgtg
      481 gcgattacca atgtggagat gaaacgtgcc acgcttgagt tgcataacca accacagcac
      541 ctttttttac gtaacatcag ggttatgcag caatccgcga cgggacccgc gcttaagatg
      601 cacttcgatc tccgtcagga tgtgcgcggc aagtttatgg caaaacagga cacattactc
      661 tcgctggcga atgtccatgc ggtaaacgaa agcgggcaaa gctcagttga catcgaccgg
      721 gtaaaccatc aggtggtgaa tgtcgaagcg gtgaattttc gactcccggg acgggagcgg
      781 taactttgcg accattcctg gctaaagtga cactccctgg gattaagatt actgcattgc
      841 gaagttaagc ggcgtaacat acgctgcatc ggagtaatgt aattcatact ggctaaaaca
      901 agctaaaaag ctataattca gcaacaattg aataggtgaa tgacttaatg attaatttga
      961 aagcagttat tccggtagca ggtctgggga tgcacatgtt gcctgccacg aaggcaatcc
     1021 ctaaagagat gctaccgatc gtagacaagc cgatgattca atacattgtc gacgaaattg
     1081 tagctgcagg tatcaaagaa atcgtgctgg tgactcatgc gtctaagaac gcggttgaga
     1141 accacttcga cacctcttac gaactcgaat cgttgcttga gcagcgtgtt aaacgccagc
     1201 tattagccga ggtgcagtct atctgtcctc caggcgtgac tattatgaac gttcgtcagg
     1261 ctcagttact gggcctgggt cattcaattc tttgtgctcg tccaattgtt ggggataacc
     1321 ctttcgtagt cgtattacct gatgtggttc ttgatacagc gagcgcagat ccgctgcgct
     1381 acaacctggc tgccatggtt gctcgtttta atgaaaccgg gcgtagtcag gtgctggcta
     1441 agcgtatgga aggcgatctg tctgagtact ctgttattca gaccaaagag cctttagata
     1501 acgaaggtaa agtcagccgt atcgttgaat tcattgaaaa accagaccag ccgcagactc
     1561 tggattccga tctgatggca gtagggcgct acgtgctttc tgcggatatc tgggcagaac
     1621 tggagcatac ccagcctggt gcctgggggc gtattcaatt gacggatgct attgctgagc
     1681 tggctaaaaa acagtcggta gatgcgatgc tgatgacggg cgacagctac gactgcggga
     1741 agaaaatggg gtatatgcag gcgtttgtta agtacggcct gcgtaacctg aaagaagggc
     1801 cgaagttccg taagagcatt gagaagttgc tcggagaata ggcaagacga aagattaatt
     1861 atattagtaa tacttcatga taaatggcag gggaagactc atgatgctat cagtatacag
     1921 gcatgtcttc actgcctttt ttatgataaa aatcaagtag taaaaagatc aatgctctac
     1981 cttttcttgt agcaaaaatc gatttcttct tgtttcttag ttagattaat acgacaatat
     2041 ttgggatgtt ttggggctaa atgtgtcaaa atgtaatcaa taattgatag gctaagcccc
     2101 ctcaaaaatt ggagtgtaca gtacactggt agctgttgag ccaggggcgg tagcgtgcct
     2161 gattaaatta acatttctgt ggcaaaataa gctaatttta tgttaaaggc taatttagaa
     2221 aaatataaaa tcaaataatt taacacgtaa ttagcataaa agattaatac aatttcggag
     2281 actacatgac tatacttgtg acaggtggcg ctggttatat tggttcacat accgttttac
     2341 agttaattga gggcggatat gatgtggttg tgcttgataa cctgagtaat tcatctcaag
     2401 agtcacttca tcgtgttggt tctttggttt cgaaaaaaat tccattcatt gaagctgata
     2461 tcaacgataa acaaaaactt gaagaagttt ttaaaaacta cgatatcgat gcagtgattc
     2521 attttgcagg attaaaatct gtgggtgaat cggtaaaaaa accgctggaa tattatatta
     2581 ataatgtcag tgggaccctc accctgcttg aagttatgaa gcaagcaagt gtttataagt
     2641 tcatttttag ttcgtccgca actgtttatg gtaaccattc tccggttccc aacctggagg
     2701 aatatcctat tggaaatgct tcctgcccct atggtactac taaagtcatg ctggagcagg
     2761 ttttatcaga ctacgcgaaa tctgatgata aattgaagat tattgctctt cgttatttta
     2821 accctacagg cgcacatcct agtggtctta ttggggagga cccgaacggc attccaaata
     2881 atcttgtccc ttatatttct caggttgcta ttggaaaatt agaaaaattg tccgtttatg
     2941 gtggcgatta tgaaaccatt gatggaacag gggtacgcga ctttatccat gtagtagatc
     3001 ttgcctcagg ccatgttagt gctttaaggc atattgataa attacaagga tatgacgttt
     3061 ttaatcttgg caccggcaat ggtgtatcag ttttacaagt aattgatgcc tttgaaaagg
     3121 caagtgacaa gaaagttaac tatgaaattg tcgccaggcg agagggcgat ataggatctt
     3181 cttgggctga tgtctctaaa gcagaaaggg ttttaggctg gaaagccaag tacaatattg
     3241 aagatatgat ggctcatacc tggaattggc aaaagcaaaa ccctaatggc tatggaagct
     3301 agtacttatc tatttaatat cataatggcg tatcaatgaa tttatttttc atagtcgata
     3361 agttggattg ggcattcgga aaaatagccc aaaatatagc aaaagagttg agtgacttta
     3421 atgtaaaaat agtttgcacc gatgatttta aaacggtggc ggaccttgtt ttacacttgg
     3481 ataaaaacgt aaaagaaaag agtatcttac actttttctg gcgtgactat ctcatggaag
     3541 tgatgaactt cactcagcgg aatccccagt ataaagaaat tttgatcagc aatattgtca
     3601 ccacacatat tcctgatcac ctattcactt atgatgatat cgcgaactat gagagacgaa
     3661 ttcctcttat gaattttgtg gatgggtatt ttgttacatc cgcaaagttg aaagagctat
     3721 attctgaact gtctgatttt ccacctcctc atagtgttat ctatgataat ccagaaattc
     3781 ctatgagcga aggaaatagt catgataata gcgatagaaa aaaactcgta tggattggaa
     3841 atagcaaatg gggcgaatat cttggttata aagattataa aggcctgaat aaaatagttt
     3901 tgccggctct ggataaatta aaaaaatctg gatatacgtt tgattttatt gagtttgata
     3961 gttctaaggg caagaccgaa cgtgaagtaa ttcttaaaac actgtctgat gcagatattc
     4021 tactcatcag ttctgaatgt gaaggtacgc cattgccact tcttgaagca atggcaaaca
     4081 gttgcgctat tgtgtcaaca gacgtcggca tagcaaatga agtgttacct gaaaagcagc
     4141 ggcagtatat tgtgtctcgg gatgccgagg cattttatga ttctttgaga aatcttcttg
     4201 atgatcaacg tggtcttaaa gaattacaaa gaatgaatta tttagcatat cgtcagcaat
     4261 ttgtagatga tggccttata gctgataaat gggcattgtt cttcaaagac atgtgttcaa
     4321 aatcgcaaaa tgaatttaag aatatattcc ttcgcgagca gaaagcgcca tcgttgaaag
     4381 aacgtttaat ttcaaaaact atttataatc taagcaggct tgctctccgt ttgaatttga
     4441 tgaatacgct gaagcaatac agtctgctac gaaaaatata ttataaggtt gctggtacaa
     4501 ctaccaatca agttgattat gatttgttgg atgagttcta tagcaatgca atagcggata
     4561 aagaagtctt agcattttac tcggcctatt ggtctggtgt tgccacatca acagccagtt
     4621 tctttaaaga tgatagtatc caatatccgt actattcata tgagttccca caagtttcta
     4681 accatgtcta tctaaacagg ttggctgaaa aacttgctgc ttcgaagaca ctaaaaagtg
     4741 tgatcatgag cggtggaaca caattacaaa tggaacttgc taaaaagatt aaggaattaa
     4801 atccaaaaat aaaaatattt tttgcatggc atggctcacc tgctcagtgg gttgactcct
     4861 cgcaatattc aacttttgat ggatggtatg aactttatcg ggaacggatt gttgatgggg
     4921 tcatctcgtt taagcctgag ctagatgaaa tacttaatgc atacggtatt cgtgcattct
     4981 cagtatcgaa ctatgctgta tcaggcactt cgttttctaa aaagttagct gtacctgatt
     5041 cgggcaattt ccgcgtcggt ttgtttgccg caatgttcag ttggtataaa aatccatttc
     5101 ctcagttact agcgattggt tcattaaaag ggtgtgagtt ggttaccaac ttgcatcttg
     5161 aaaataatat gaagtggatt acctcaaaca tcaaacttac ggcattatca gagaatttaa
     5221 ataataagcg gtttatcgag ctgctatctc gtttacatgt tgtgtgctat gtaacgaata
     5281 cggaatgttc accaatgatc gcgctggaat cagcaagcgt tggaacgcca tgcgttgtag
     5341 gtccagccgg aaacatatat aaaggttttc ctgagttaga attgtatttg gttgaaaaag
     5401 aggttgataa tccaactgca atcaggaatc ggttacaatt agttcgtgat aattacgcgg
     5461 aagttaaggt tttacttaac gcatttgttt tggaatacaa ttccagatta gaactaatta
     5521 aagagaagat gtataaagag ctgaagcaat gaaagaatca ttaacagata tatattcgtc
     5581 aataaaatcc tggcatcttt ggactacatt aggttggttg gaattaaggc agagatataa
     5641 aagatccatt gttggaccgt tttggattac attaagtatg gcggtcctta ttattgcttt
     5701 aggggtaatt tatggagaac tatttaaatt agaagttaaa gagtatctcc cgatgctagc
     5761 agttggtttg gtgttctgga actttattag tggcgttata aatgaagggt gtgtaacttt
     5821 catatcgtcc agctctttta taagtcagtt accaactaaa aaattcatat acattatgca
     5881 aatgttatgg cgaaatttta tgatgctttg ccataatata gtaatagtga ttggtgtgtt
     5941 gattatattc aacgtctttt cgttgaagaa tttcccgctt tttatacttg gatttatgat
     6001 cgtagttgtt aatctgatct ggattgcaac tttatttgca gtaatttctg tacgttttag
     6061 agattttccg caaatggtca tgagttttat gcaggttgtc ttttatataa cgccgatatt
     6121 attttctgga acaatgttgg ctaaatatag cttgctgctg aagttaaacc catttgcttg
     6181 gtttatcgag attattcgct cgcctttagt agggaaaatg cccgagttat actgctatta
     6241 taattctatt atccttgcat gcgtaggaac agttatctca ctaattacat ttgcaaaatg
     6301 tagaaatcgc attgcatatt gggtgtaaat tattatgtct catttgattg acttaaaaga
     6361 tgtgggtgtc gaatttccca tttacgacgc taaaagtaga tcgtttaaat cgcaggtggc
     6421 taacttaacc cgcggtgtta tttcttcaaa aaaagaaagc agcacggtta cggttaaatc
     6481 attagacggt ttaacgttta gtctgaaaga aggtgataaa ctcggactta ttggaaacaa
     6541 tggcgcggga aaatctacgc tactgaagct gttggctggt atctatgaac caacctccgg
     6601 cacaattaaa agaaagggta agatagttcc actgttggat atcgctctag gaatggatga
     6661 tgattccaca ggataccaaa atataaaact acgcggtttg ttacttggta tgacgaatgc
     6721 agaaatcgaa tccaaaatag aagagatcgc ttgcttcaca gaactaggtg attacctgaa
     6781 tctaccaatt cgtgtctact ctaccgggat gcgcgtgaga ttagcatttg cagtatcaac
     6841 ttcagttgat ccagatgtac ttttactcga cgaaattatt gggactggtg atgcttcttt
     6901 cttaaataaa gcaaagaaaa gattccagga gttgcaggag agggcaaagg ttgttgtgct
     6961 atcttcccat gacaacaatg tcattctgaa aacttgtaat aaagttctgt ggttagaagg
     7021 tggtaaacca aagatgattg gagatccgga agaagtatta aataaatata tggatagcgt
     7081 agtttaaaaa cataggtggt atgagtgaag attgattatg tcattacagg catggatgtc
     7141 ggaggcgctg agatgcaggt tgtcgaattg cttcttgagc ttcaaaaatg tgggcattct
     7201 gttcgattaa tttcgcttac accaccagtt gatttgattg ataagctaat cagtaatgac
     7261 ataccagttg tttcattggg tatgaaatca aaattagctt tacctatggc tgcatttaaa
     7321 ttagcaatgt tgatcagaca aaactctcca gatattgtgc attcgcatat gtttcatgcc
     7381 aatatcttgg tacgtttcgt aagagcactc ttgggaaggc gttcatctat tatttgtact
     7441 gcacacagcg ttcgtgaagg tggcagtgcc agagactggc tctatcgttt gactaataaa
     7501 ttaagtgact tgaatacagt tgttagcgat gctgcacggc agcgatttat taacgacaaa
     7561 gtatttccac ctgagaaaac acttactgtt tataattgta tcaatattga tcatttttgt
     7621 atcatcgata gacagggcag gaaacgattt cgctggataa cagttgggcg gcttgtaaaa
     7681 ataaaaaacc aactgttgat tttgcaagct atgatgcagt tgccacatag tgaactcatc
     7741 atagttggag agggcgaaga acggcttaca ttgcaaacat ttatcgatca aaattctctc
     7801 agcgagcgag ttactctctt gggaaaaaag gataatgttg ttgattatta ccatgattcc
     7861 gatgcctttg tgctggcctc tgactatgaa ggttttgctc ttgtcgttgc cgaagctatg
     7921 gcatgtggat taccagtggt cgcaacagat tgtggtgggc cagcagaaat tattggaaat
     7981 ggacaggatt ttggcataac aatatcggtt aatgatgtac atcacttaac tgcagcgatg
     8041 caacagattg aatcattaga tatcgaacaa cgtaaaggaa gcggctatcg tgctcgggaa
     8101 agagtcattg agaaattttc tgctaaaaaa atcgtatctc aatgggaaga tatatacctg
     8161 tgcatacaga aaaacagaat ttagaactca cctatgaaaa tagcattaat cggtactaca
     8221 gcagaaagtc taatccaatt cagaaaagaa ctgattaatt tattacataa aaatggccat
     8281 gttgtatatg catttgcaat tgactatgat gatgtgacaa aagaaaaagt taaatcattt
     8341 ggcgctatac cagtacatta ttgtttcagt cgtacagggc taaatccatt ttctgatgtt
     8401 atcaacacct ataaattgta taaaatttta aaatcacttc agttagactt ggcattttct
     8461 tatttttcaa agccagccat ttttggtact ttagcagcaa agttcgcaag aatacaaaaa
     8521 cgatatgcga tgcttgaagg tcttggtttt ttctttacca attctggagg acaggtttca
     8581 ttacgaacta aattactaaa aaaaatattg gtttcgcttt acaaagtgag tttcagacac
     8641 attgaaagtc taatcttgct taatgcggat gataagcgag atcttttagt taatgaaaaa
     8701 attcaagtaa aaaaggtaca tatattaggg gggattggat taaatatgtc tgattatccc
     8761 tactgcccac ctcctgtcga gccagtgtct ttcatttttg tcgccagatt tttgcaagaa
     8821 aagggagttt atgaatttat tgaggctgca aaaatagtca aaaagaagtt tcctgaaact
     8881 catttttgta tgctgggcca tctggatctt cataacccgg gaagcttaac tatagaacga
     8941 cttaatgatt tgaaatgtaa taacatcatt gagttacctg gtcatgttga taacgtacag
     9001 gagtggcttg ctaaagcgag tgtattcgta ttgccttcct ggcgtgaagg gtttccgaga
     9061 agtacacagg aggctatggc catgggccgc gctgtcataa ccagcgatgt gccaggttgc
     9121 cgagatacag tggttgatgg cgttaatgga tttttgatta agccacgttc ttctcatgcc
     9181 ttagccgaaa aaatgctctg cttcttacat caacctgagc taattaccca aatggggaat
     9241 gcaagtcacc aaatagcttt acaacaattt gactcaagta tagttaattc gaagctaatg
     9301 aagatactac gtgtagattt tgaaaataca aaatctaatg tctgttaaat catataaata
     9361 caactttata aaaaacacaa tttagtagga agattatgga aagattaaat ttgagtgaaa
     9421 aacctgctca ctctttacag gaatcggcta ttcattgtgc cagatatgct aatatcttac
     9481 atcttgttaa agataaagta gttctggaca ttgcctgtgg tgagggatat ggctcagcac
     9541 tattaatgaa agcaggagct aaacgagttg tgggggtgga catctctgaa gagtcaatcg
     9601 agcgtgcaaa gaaacttttt gggaaatatg atgtagaata tattgtaagt gatgcaaata
     9661 ccatctcaga gcgttatggc gaagactttt ttgatatagt tgtttcaatt gagacaatag
     9721 aacacatcaa tacccctgac gtctttctta gttctatcaa aaaaactgct aaagaaaatg
     9781 cgattttcta tataacttgc cctaacgatt attggtacta tccaaataat gaacaatcta
     9841 atccttgtca tgtacgaaag tatacttttc aagaattcaa agagcttagt acaggggttt
     9901 tgggtaataa tgtccaatgg gcatatggtg gttctgtttt tggattcggc acagtctctg
     9961 ctaacaatcg aggtcttgaa aagataggtt cttcatggat ggaaataagc gagtcagaaa
    10021 attcaattaa tgttttaaac acagagattg acgctgttaa tgaaaataat tgtagtttct
    10081 ttgtgggctt atggaatgcg cctgaaacaa actttagcaa cagtactttt ccaataagta
    10141 tggatgctta ttcgcgcatg acagaagaat ttgagtcaaa tgtaagttct gtacttcgtg
    10201 aagatcaggc ggaaaataaa aaagccatat caatattaaa aaaagatatg aaacaattaa
    10261 caatgaattt gagaaaatca aatcttttat tatctgcatt aaaaattgaa aatgttacac
    10321 tgcgtaagaa tatttccgaa ttgcaacaac aactcgccaa acaaatcgcg atgtatcatg
    10381 acgtaacaaa tgcaaaaata atttagaatt agaaaacgcc gatttaattt cgttgcatgg
    10441 ggatctagca actaaaaatt catcattgat ggaacgaatt tcgcaaatgg aaattccata
    10501 ttatcgatat ttaagactct ctgctcttct tccgggtttt ttgaaaaaaa ttatactaaa
    10561 aattgtgcgt tttatcagga aataaaatat gtctgcacgt ttaaaattat tgcctgggtt
    10621 aaagtcaact gagtatgtgt attcagatct tcatgcttta cttgatacta atggtgggag
    10681 ttccttaggt ccgaacattg gtagtgatgg ttctaaccta acaataacat gtttatcgat
    10741 gagcagagtt tttcttactg aaaaacttgt taattctata tatcagcata taccttattt
    10801 taaaggtgat attctgattg ttgataatgg cagcacagta gaagaacttt caattttaca
    10861 aaatttaagt gataggatcc cgttaaatat tagagttgtc gagcttggta ataattttgg
    10921 cgtaagtggt ggaagaaaca aaactttaga gcatataaaa acagaatggg caatgtttct
    10981 cgataatgat atttatttca taaataatcc acttccgaga ttgcaaaatg atatttcaag
    11041 acttggttgt cattttatca atatgccatt gcttgattct gacggagaaa cattattcgc
    11101 aaatggaggg aatgttttcc tcgatattga tgatgattcg gtgcatgttg gtgcaggaag
    11161 tgcatgtatt caggaaaaaa caattacata tgatggtgaa ggcttccttt ctacatttct
    11221 ttttggtggt gcgagtgtta ttaaaatcgc gaccctgaaa aatttaggga agtatgacga
    11281 aaatatgttt attgggtttg aagacattga tttatcgatc cgtctttacc agtcaggaat
    11341 gaaagttggt acatgtggtg caatttcttt aatccatgat cacccgaagc ctagttctaa
    11401 caaagataaa gattatgaga aaattcgctt cacgcgaagt atcttaaaag aatccgcgga
    11461 ttatcttgaa aacaaatggg gaatggtttt ctggtcagct ccagttgatg attggttgga
    11521 agagaagcaa cgtagttttg aactgacaac tcagcataat gataatttgt cccaattcga
    11581 tgacaataaa aaaggcgcga cttatgattt atctgtgtca aaaccgaaaa ttgcattgat
    11641 tattgatact gaaaactggg cattctcaaa tattgcaaat caaatagtca attatctgtc
    11701 agattcatat gactttacaa taataccaac tgaaattgtt gataatatca gtcaggttat
    11761 tatgatgact agaaattatg atataacaca tttcttctgg cgtgaatcgc ttagacttat
    11821 atatgatgag tattatataa actataaccg gactatcgga tttgatgagc tcagctttaa
    11881 aaaagagttc ttggatggaa gaataataac cagtagcgtt tatgatcatt tattcctgga
    11941 tgagcaagct ataaaattaa gaaagacatt ttataacgat ttaataactg cttatacggt
    12001 tagttcatca aaactatatg acatctactc atccatagtt gagtatccta agccatcagt
    12061 tcttgcggaa gatggggtta atttaaaact attttatcca attaatcttg aacgttttga
    12121 taatatagaa tcgagggcct tgcgcgtagg ttgggctggg aattctaaat gggcgggaga
    12181 gttagaggat ttcaaaggtt accattcttt attaaagcct gcagttgagc aattacaatc
    12241 agaaggatta aatattgaat tagtccttgc cgatcgtcaa ctcggattta ttcctcatga
    12301 tgaaatggta aaatattata gccaaattga tgtatatgtc tgtccttcaa aaattgaagg
    12361 cacaccaaac cctgtccttg agtctatggc atgtggcgtt cccgtgataa gtactgatgt
    12421 tggtgtggtc aaagatgctt ttggtgagat gcaaaaagaa tggattttac cagttagaag
    12481 caaggatact ttgatagata aacttagaga tttttatcat aagcgtaatt cagtggtaaa
    12541 atgtctatct tcagaaaatt tgcaacaaat aaaaaaatgg gattggaaag ttaagtctga
    12601 gaactttcgg acttttttcg acaaagtact agaatctaaa aagcacagcg agataagcaa
    12661 taaaatgtga tcaagatatc atttgatccc tggtcctagt ttttttatca ttatcgcaac
    12721 ttaacaagct cgtggtatct acacctgaca ggagtatgta atgtctaagc aacagatcgg
    12781 cgtcgtcggt atggcagtaa tggggcgcaa cctggcgctc aacattgaa
//
LOCUS       DACAOP010000116        12445 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.116, whole genome shotgun sequence.
ACCESSION   DACAOP010000116 DACAOP010000000
VERSION     DACAOP010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12445
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.116"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            184..1683
                     /locus_tag="IT892_003825"
     CDS             184..1683
                     /locus_tag="IT892_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAP3136980.1"
                     /translation="MSETFLQMKHITKRFPGVLALNDVQFTLRRGEVHALLGENGAGK
                     STLMKILSGVYQPDEGEIIFEDKPVSFSDPLSAQNVGITIIHQEFNLFPELTVEENIF
                     IGREFCKKNRWRLDEKQQRQATIEILQKLNLAIKPDTLVADLTVAQQQMVEIAKAISV
                     NARILIMDEPTAALTETEIESLFRVTRLLKEQGTGIVYISHRLEELALIADRATVMRD
                     GQYISTVDYECVKISDLIAMMVGRDLGNIYPRREALQQRIPVLKVNGLTRKGVLNDIN
                     FTLYRGEILGFAGLMGAGRTELARAIFGADSIDSGTLKLNGKETVIKDISDAIQQGIS
                     YLTEDRKKEGLALNLSVERNIMLGNYPEYSDRFGNVDSRRCQQTSEEQVKALRIKTPN
                     LEQAALNLSGGNQQKIIIARWVCKDTDILIFDEPTRGIDVGAKLEIYELMNRLVAKGK
                     SIIMISSELPEVLGMCDRILVMRSGRITGELSAKEATQEKIMQYATLED"
     gene            1687..2670
                     /locus_tag="IT892_003826"
     CDS             1687..2670
                     /locus_tag="IT892_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP3136981.1"
                     /translation="MTISVTSPDSNNKKIKINKELLMRLAPLFSLIILVLFFSFSSPF
                     FFNTENIMTIALQTSVIGIMAIGVTFVIITAGIDLSLGSVVAFSGVAVGICATLGLPL
                     PVCIIAGVLAGGLCGYVNGLLVTKMTIPPFIATLGLMMSVRGINMVMTDGRAIYFADY
                     PMFKTLAQGRLFDVLPYPVFYLVIVALVGAYILKKTVIGRYVYAVGSNEVAAHLSGIK
                     VQRVKIFVYAFCGLLTGIAGVILASRLNSGQPTVGVGYELEAIAAVVIGGTSLMGGIG
                     TIGGTIIGAFIMSVLKNGLNLMGVSQFWQMVAMGVVVVAAVYLDTLRKKIR"
     gene            2744..3694
                     /locus_tag="IT892_003827"
     CDS             2744..3694
                     /locus_tag="IT892_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003034057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP3136982.1"
                     /translation="MKTRHFIYALSLLACVTSSALAKDLNLPVVSKGFQHEFWQTVKM
                     GTEAAAKELGDKTSYVGPADETQIAEQIQLVENAMAQKPNGLLLAALDANALAPLVET
                     ANSRGIKVVTFDSGINSDIPVSFVATNNRKAGAQAADALAAQVNNKGKVGIIAHVAGT
                     SSAIERSEGFMERMKEKYPDIKVLPVQYSDGDPQKAMDKTIDMIQANPDLAGIYGTNE
                     GSTLGVANAIDSQNLKGKVKVIGFDSTEAIINFLKNGVIQGFVVQDAYQIGYQGIKTL
                     NAALSGQAVEKEIDIPVKFVNAENINTPEIDKLLHPFGKK"
     gene            3748..5328
                     /locus_tag="IT892_003828"
     CDS             3748..5328
                     /locus_tag="IT892_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAP3136983.1"
                     /translation="MHNGYFLGVDVGSASVRAGVYSASGHRLAFATAPVSQFRPGGER
                     VEQSSAEIWQQVCKTVKEATALAGIPISAIRSLGFDATCSLVVLDEQGQGLAVSSGGS
                     ANHDIIMWMDHRATVETAQINATKDPALRYVGGEVSVEMELPKLRWLKTHLPQTWQAA
                     HRFFDLADFLVWKATGRDVAGLCTLTCKWNYLAHEQRFSHSLLESVDLTDMLERIPAE
                     ILPPGAAVGTLTATAAEELGLTTNVIVASGLIDAHAGGMALAGAQPSGTLALISGTSN
                     CHMLCSEKEIFTPGVWGPYWSAMLPNYWLTEGGQSAAGALVEWTLQESGASANLFNKA
                     QQRGCHPIQLINEWVAALEANESEPTRNLHVLADHHGNRSPRARSDARGSVYGLTLER
                     GENQLARLYLATLQAIAFGTRHIIETLRENGHTITRLTLCGGATHNPLWLREYADVTG
                     CDIHLMQEEDAVTLGAAISGAVASGAWGDFTSACKAMVEAGEVIQVNPQRREFLERKY
                     RVYLTLWEQQQAVNQLMQ"
     gene            5393..6391
                     /locus_tag="IT892_003829"
     CDS             5393..6391
                     /locus_tag="IT892_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP3136984.1"
                     /translation="MAKTVEQIASDLNLSVTTVRLVLNGKAEQYRISVKTQTRINEYV
                     ERYGYIINHSARSLKLNKTDTLGLIVPNISNVFFATLAEKLEQRCRRSGYQLTISCTY
                     DDVDYENKLTKAFIARNVDGLFIVPSTLENQQHHLRKIRKPMVLLDRDFKYTDNALVE
                     SNNISGGEKLTQNILEAGQAPVWFLLGDAGLPSISDRLTGYLNALAKKGITHRDWVRE
                     GPVNTPEGGYVIMEKLIEEQGCPQAFIASSLPVLEGAVRAIRDRLGAVPPEINIGTFD
                     EHPMLGFLANNVWSMQQDENAWAEKAFEMMLSAIEERPVKKTVKVEMKLIKRIRKK"
     gene            6524..7171
                     /gene="fucA"
                     /locus_tag="IT892_003830"
     CDS             6524..7171
                     /gene="fucA"
                     /locus_tag="IT892_003830"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HAP3136985.1"
                     /translation="MERTRLSREIIETCLEMTRLGLNQGTAGNVSTRFENGMLITPSG
                     IPYERMTENMIVYVDGNGKYEEGKIPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVS
                     ILNRPIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIAC
                     EVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE"
     gene            7199..8347
                     /gene="fucO"
                     /locus_tag="IT892_003831"
     CDS             7199..8347
                     /gene="fucO"
                     /locus_tag="IT892_003831"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417279.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAP3136986.1"
                     /translation="MANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQC
                     GVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLGVFQNSGADYLIAIGGGSPQDT
                     CKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTINYVITDEEKRR
                     KFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYITRGAWALTDALHI
                     KAIEIIAGALRGSVAGDKDAGEEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPH
                     GVANAILLPHVMRYNADFTGEKYRDIARVMGVKVEGMSLEEARNAAVEAVFALNRDVG
                     IPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAW"
     gene            complement(8452..9297)
                     /gene="xni"
                     /locus_tag="IT892_003832"
     CDS             complement(8452..9297)
                     /gene="xni"
                     /locus_tag="IT892_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease Xni"
                     /protein_id="HAP3136987.1"
                     /translation="MRGLFPFSQPAIACSGIECYPYRLIFKGVIVAVHLLIVDALNLI
                     RRVHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPP
                     MPEELHDEMPALRTAFEQRGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGY
                     CQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPK
                     SATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQ
                     LRLVR"
     gene            complement(9318..10685)
                     /gene="sdaB"
                     /locus_tag="IT892_003833"
     CDS             complement(9318..10685)
                     /gene="sdaB"
                     /locus_tag="IT892_003833"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase II"
                     /protein_id="HAP3136988.1"
                     /translation="MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTR
                     VVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPGFIQDVNTHGRLMLANGQ
                     HEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQ
                     DSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRG
                     GIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPC
                     IERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMK
                     IVACD"
     gene            complement(10743..12032)
                     /locus_tag="IT892_003834"
     CDS             complement(10743..12032)
                     /locus_tag="IT892_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HAP3136989.1"
                     /translation="METTQTSTIASKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPIN
                     AGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLIT
                     LLYFFAIYPILLVYSVAITNTVESFMSHQLGMTPPPRAILSLILIVGMMTIVRFGEQM
                     IVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVM
                     VFSFNHSPIISSFAVAKREEYGDMAEQKCSKILAFAHIMMVLTVMFFVFSCVLSLTPA
                     DLAAAKEQNISILSYLANHFNAPVIAWMAPIIAIIAITKSFLGHYLGAREGFNGMVIK
                     SLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMY
                     AIQKVPAMRKYSGHISNVFVVVMGLIAISAIFYSLFS"
BASE COUNT         3251 a         2851 c         3246 g         3097 t
ORIGIN      
        1 aatttgtata cctaaaatag ctttaaaagg cgatcgctaa ctcgagttag caaaatgcta
       61 agaatagatt gatgcgatga atatttattc aaaggttatt cgtatcacag tggagatggc
      121 tttagtagcg acgtttatgc cgtacttcac attttcagtt tctgattatt gaggaaagct
      181 gcaatgtccg aaacattttt gcaaatgaaa catatcacca aacgctttcc tggagtgttg
      241 gcgcttaatg acgtgcaatt taccctacgc cggggcgagg ttcatgcatt attaggtgaa
      301 aatggtgcag gaaaatctac cttaatgaaa attttgtcgg gggtttatca acctgatgaa
      361 ggcgaaataa tttttgaaga taaaccagtc tcattttctg atccgttaag tgcgcaaaac
      421 gtaggtatta ctattattca ccaggaattt aatttatttc ccgagcttac agtagaggaa
      481 aatattttta tcggcaggga gttttgtaaa aaaaatcgct ggcgtctgga tgaaaaacag
      541 caacgccagg cgacgattga aattttgcaa aaattaaatt tggcgatcaa accagatact
      601 ctggttgccg accttacggt agctcagcag cagatggtag aaattgccaa ggccatttca
      661 gttaacgcca ggattctcat tatggatgaa cctactgcgg cgttaacaga aactgaaatt
      721 gaaagcttat ttcgcgtcac ccggttattg aaagagcagg ggaccggcat tgtgtatatc
      781 tcccaccgtc tggaagagtt ggcgctaatt gccgaccgcg cgactgtaat gcgtgatggt
      841 cagtacatca gcacggtgga ttatgagtgc gtaaaaatca gcgatctgat tgccatgatg
      901 gttggtcgcg atttggggaa tatctatccc cgccgcgagg ccttgcagca gcggattccg
      961 gttctgaagg taaacggact gacgcgcaaa ggcgtcctga acgatattaa ttttacgctt
     1021 tatcgtggcg agatcctcgg ctttgccgga ctgatgggcg cggggcgtac tgaacttgcg
     1081 cgtgcgattt ttggtgcgga ttccattgac agcggaacgc taaaattaaa tggtaaggaa
     1141 accgttatta aagatatttc ggatgctatt cagcagggaa ttagttacct gacggaagac
     1201 cgcaaaaaag aagggctggc gctgaattta tctgttgaac gaaatattat gttaggaaac
     1261 taccctgagt attccgatcg ttttgggaat gtcgattcgc gtcgttgcca acaaaccagt
     1321 gaggaacagg taaaagcgtt aaggattaaa acgccaaatc ttgaacaggc ggcattaaat
     1381 ctaagtggag gaaaccagca gaaaattata attgcacgtt gggtgtgtaa agatactgat
     1441 attttaatct tcgatgaacc cactcgcggc attgatgttg gcgccaaatt ggaaatctat
     1501 gagttaatga atcgcctggt ggcaaaaggg aaatcaatca tcatgatctc ctctgaattg
     1561 ccggaggtgt taggaatgtg cgaccgtatt ttagtgatgc gcagtggtcg aattaccggc
     1621 gaacttagcg caaaagaagc gacacaagaa aaaatcatgc aatacgcgac gttagaggat
     1681 taaattatga ctatctctgt aacctctcca gacagtaata ataagaaaat aaagataaat
     1741 aaagaacttt tgatgcgcct tgcacctctt tttagcttaa ttatattggt gctatttttt
     1801 agtttcagct ctcccttttt ctttaatacc gaaaatatca tgacgattgc tctacaaacg
     1861 tcggtaatcg gcattatggc cattggggta actttcgtca ttattaccgc tggcatcgat
     1921 ctttcattgg gctccgtggt ggctttttct ggtgtcgccg taggtatttg cgccacgctg
     1981 ggcctgccgc tgcctgtgtg tattattgct ggtgttttgg ccggtggatt gtgcggctat
     2041 gtgaatggtt tgttggtcac taaaatgacc attccaccgt ttatcgctac gttgggcctg
     2101 atgatgtccg tcagaggcat caatatggtg atgactgacg ggcgcgccat ctattttgcc
     2161 gattacccga tgttcaaaac gctcgctcag ggacgcttat ttgatgtgct gccttatcct
     2221 gttttctacc ttgtcattgt agcgcttgtc ggcgcttaca tcctgaagaa aaccgtcatt
     2281 ggtcgctatg tctatgccgt aggcagtaat gaagttgctg ctcatctttc tggtattaaa
     2341 gttcagcgcg tgaaaatttt cgtctatgcc ttctgtggat tattaacggg gattgcaggt
     2401 gtcattctgg catctcgtct caactccgga caaccgacgg taggtgtggg ttatgaactg
     2461 gaagctattg ccgcggtagt gattggcgga accagcttaa tgggcggtat tggtactatt
     2521 ggcggcacaa tcattggcgc tttcattatg agtgtactga aaaatggcct caatttaatg
     2581 ggcgtctccc agttctggca aatggtcgcg atgggcgtcg ttgtggtcgc tgccgtttac
     2641 ctcgatacat tacgcaaaaa gattcgttga cttaggctcc ctgttttatc gggaaacaac
     2701 tgccctgacg ttaagggtga ttcactcaga acggagtaca acaatgaaaa ccaggcattt
     2761 tatctatgcg ttatctctgc tggcctgcgt aacttccagc gcactggcga aggatttaaa
     2821 tcttccggtt gttagtaaag gtttccaaca tgaattctgg caaaccgtaa aaatggggac
     2881 tgaagctgcg gctaaagagt tgggggataa aaccagctat gttggcccgg ctgatgaaac
     2941 gcaaatagcc gagcaaattc agttagtcga aaatgcgatg gcgcagaaac cgaatggctt
     3001 gcttctggca gccctcgacg cgaatgcgct cgccccactg gtagaaacgg caaattcacg
     3061 cggtatcaaa gtggtgacct ttgattcagg catcaattca gacattccgg tgagttttgt
     3121 cgccaccaat aaccgtaaag caggtgctca ggcagctgat gccttagctg cgcaggtaaa
     3181 taataaaggg aaagttggga ttatcgcgca cgttgcagga acatcttccg ctattgaacg
     3241 ctcggaaggc ttcatggagc gtatgaaaga aaaatatcct gacattaaag tcttacccgt
     3301 tcagtacagc gatggtgacc cgcaaaaagc gatggataaa actatcgata tgattcaggc
     3361 caatcccgat cttgctggga tctatggcac caatgaaggt tcaacgctcg gggtggcgaa
     3421 tgccattgat agccagaatc tgaaaggtaa ggtgaaggtc attggttttg atagtacgga
     3481 agcgattatt aacttcctga agaacggggt cattcagggc tttgttgttc aggatgcata
     3541 ccagattggc tatcaaggga tcaaaacgtt gaacgcggcc ctttcggggc aagccgttga
     3601 aaaagagatc gatattcccg tgaaatttgt taatgccgag aatattaaca cgccagaaat
     3661 cgacaaactc ctgcacccat tcggtaagaa ataaaaaaat tggggatgaa ttctcatccc
     3721 cgttatctcc agcgtcaggg aggctttatg cacaacggtt attttctcgg tgtcgatgtc
     3781 ggatcggcca gtgtcagggc aggcgtttac agtgccagtg gccacaggct ggcattcgct
     3841 actgcgcccg tctcccagtt tcgccctggc ggcgagcgtg tcgaacagtc ttcggcagag
     3901 atctggcaac aagtttgtaa aacggtgaaa gaggcgacag ctttggcagg catccccatt
     3961 tccgcaattc gctcactggg ttttgacgct acctgctcgc tggttgttct tgatgaacaa
     4021 ggccagggtt tagcggtttc gtccggtgga tctgcgaatc acgacattat tatgtggatg
     4081 gatcatcgtg caactgtcga gacggcgcag attaacgcaa cgaaggatcc cgcattgcgc
     4141 tacgttggcg gcgaagtgag cgtcgagatg gagttaccaa agttacgttg gttgaagacg
     4201 catctaccgc aaacctggca ggccgctcat cgctttttcg atctggcgga ttttctggtc
     4261 tggaaagcaa cagggcgaga cgtcgcggga ttgtgcacgc taacgtgtaa atggaattat
     4321 ctggctcatg aacaacgctt tagccatagc ttactggaat cggtagacct gaccgacatg
     4381 ctcgaaagaa ttcccgccga aattcttccg cctggtgctg ccgtgggaac tttaactgcc
     4441 acagctgctg aagaattagg attaacgacc aatgttatcg tggccagtgg tttgattgat
     4501 gcccatgccg gtggcatggc gctggctggc gcgcagccat caggaacgct ggcattgata
     4561 agcggaacgt cgaattgcca tatgttgtgc agtgaaaaag aaatattcac ccctggcgtc
     4621 tgggggccat actggtcggc catgttgcca aattactggc taactgaagg cgggcaaagc
     4681 gccgcagggg cgctggtgga gtggacgctt caggagtccg gggcaagcgc aaatcttttt
     4741 aacaaggcgc agcaacgcgg gtgtcatccg attcaactga ttaatgaatg ggtagccgca
     4801 ctggaagcta acgagtcaga acccacacga aatttacatg tgcttgccga tcatcacggc
     4861 aaccgttcgc cacgagcgcg gtccgatgcc agaggcagtg tttatggctt aacactggag
     4921 cgtggtgaaa atcagctcgc gcggctttat cttgcgactt tacaggcaat agcctttggc
     4981 accagacata ttattgaaac tctgcgggaa aatgggcata ccattacccg attaacatta
     5041 tgtggtggtg caacgcacaa ccctttatgg ctacgcgaat atgcagacgt gacaggttgc
     5101 gatatccacc tgatgcaaga agaagatgcc gttacgttgg gcgcagcaat tagcggcgct
     5161 gttgccagcg gagcatgggg ggattttaca tctgcgtgta aagcaatggt tgaagccgga
     5221 gaggttattc aggtaaatcc acaacgccgt gaatttttag agcgtaaata ccgggtttac
     5281 ctgacgcttt gggagcaaca acaggcggtt aaccaactga tgcaataaga caaaagttga
     5341 aaatactttt atgattgtga tttgacgtct ggatgttaac tgggaaatac ctatggctaa
     5401 aacagtagag cagatagcca gcgacctgaa tttatcggtt acgaccgtgc gactggtgct
     5461 aaatggaaaa gcggaacaat atcgaatcag cgtcaaaacc caaacgcgta tcaatgaata
     5521 tgttgaacgc tatggttata tcattaatca ttccgctcgc agccttaagc ttaacaaaac
     5581 tgatacatta gggttgattg ttcccaacat atccaacgtc ttttttgcta cgctggcaga
     5641 aaaactcgaa caacgctgtc gacgttccgg atatcaactt acaatcagtt gcacttatga
     5701 tgatgttgac tatgaaaata aattgacgaa agcatttatc gcacgaaatg tagatggtct
     5761 ttttattgtt ccttcgacgc tggaaaatca gcagcatcat ttacgcaaaa ttcgtaagcc
     5821 aatggtttta ctcgatcgtg attttaaata taccgataac gcattggtag agagtaataa
     5881 tatttctggc ggagaaaagc tgacgcaaaa tattcttgag gccgggcagg ctccagtatg
     5941 gtttttgctg ggagatgccg gtttgccgag tatcagcgat cgtctgacag gctatttgaa
     6001 tgcgttggca aaaaaaggga ttacccatcg cgattgggtg cgggaaggtc cggtaaatac
     6061 tccggaaggc ggctatgtca ttatggaaaa actcattgaa gagcagggat gtccgcaggc
     6121 atttatcgcc tcgtctttac ctgtgcttga aggcgctgtc cgcgcgattc gcgaccgtct
     6181 tggcgctgta ccgccagaaa tcaatattgg cactttcgat gaacatccta tgctgggatt
     6241 tctcgccaac aatgtctggt caatgcagca ggatgaaaat gcctgggcag aaaaagcgtt
     6301 cgaaatgatg ttaagcgcga tcgaagaaag accagtcaaa aaaacagtta aagtagaaat
     6361 gaaattaatt aagcgcataa gaaaaaaata ataatcgcca aaagatatca ggctactgaa
     6421 caatgatatt cagtggcctc cccttactaa aaataacccc gtcttcattt gcggtgctgt
     6481 tttacgcaac aaggcgagct gaaactgtat ctggagaata gaaatggaaa gaacacgttt
     6541 atcccgtgaa ataattgaaa cctgtctgga aatgacgcgc cttgggttaa atcaggggac
     6601 agcggggaat gtcagcacac gttttgaaaa cggcatgttg attactccca gcggtattcc
     6661 ttatgaaaga atgacggaga atatgattgt ctatgttgat ggcaacggca aatacgaaga
     6721 aggtaagatt ccttccagcg aatggcgttt ccatatggcg gcctatcaaa gcagaccgga
     6781 tgccaacgcg gttgttcaca atcatgccgt tcattgcacg gcagtttcca ttcttaaccg
     6841 accaatcccc gctattcact acatgattgc ggcggctggc ggtaattcta ttccttgcgc
     6901 gccttatgcg acctttggaa cacgtgaact ttctgaacat gttgcgctgg ctctcaaaaa
     6961 tcgtaaggca actttgttac aacatcatgg gcttatcgct tgtgaggtga atctggaaaa
     7021 agcgttatgg ctggcgcatg aagttgaagt gctggcgcaa ctttacctga cgaccctggc
     7081 gattacggac ccggtgccag tgctgagcga tgaagagatt gccgtagtgc tggagaaatt
     7141 caaaacctac gggttacgga ttgaagagta atttcgtaaa gcaacaagga gaaggatgat
     7201 ggctaacaga atgattctga acgaaacggc atggtttggt cggggtgctg ttggggcttt
     7261 aaccgatgag gtgaaacgcc gtggttatca gaaggcgctg atcgtcaccg ataaaacgct
     7321 ggtgcaatgc ggcgtggtgg cgaaagtgac cgataagatg gatgctgcag ggctggcatg
     7381 ggcgatttac gacggcgtag tgcccaaccc aacaattact gtcgtcaaag aagggctcgg
     7441 tgtattccag aatagcggcg cggattacct gatcgctatt ggtggtggtt ctccacagga
     7501 tacttgtaaa gcgattggca ttatcagcaa caacccggag tttgccgatg tgcgtagcct
     7561 ggaaggactt tccccgacca ataaacccag tgtaccgatt ctggcaatcc ccaccacagc
     7621 aggcactgcg gcagaagtga ccattaacta cgtgatcact gacgaagaaa aacggcgcaa
     7681 gtttgtttgc gttgatccgc atgatatccc gcaggtggcg tttattgacg ctgacatgat
     7741 ggatggtatg cctccagcgc tgaaagctgc gacgggtgtc gatgcgctca ctcatgctat
     7801 tgaggggtat attacccgtg gcgcgtgggc gctaaccgat gcactgcaca ttaaagcgat
     7861 tgaaatcatt gctggggcgc tgcgaggatc ggttgctggt gataaggatg ccggagaaga
     7921 aatggcgctc gggcagtatg ttgcgggtat gggcttctcg aatgttgggt tagggttggt
     7981 gcatggtatg gcgcatccac tgggcgcgtt ttataacact ccacacggtg ttgcgaacgc
     8041 catcctgtta ccgcatgtca tgcgctataa cgctgacttt accggtgaga agtaccgcga
     8101 tatcgcgcgc gttatgggcg tgaaagtgga aggtatgagc ctggaagagg cgcgtaatgc
     8161 cgctgttgaa gcggtgtttg ctctcaaccg tgatgtcggt attccgccac atttgcgtga
     8221 cgttggtgta cgcaaggaag acattccggc actggcgcag gcggcgcttg atgacgtttg
     8281 taccggtggc aacccgcgcg aagcaacgct tgaggatatt gtagagcttt accataccgc
     8341 ctggtaaatg cgctgatgtg ataatgccgg atgcgacgct agctgcgtct tatccggcgt
     8401 ataagttcat taaattcaat gtgttgataa tcgtttgcat ccggcacgcc gttaccgtac
     8461 caaccgcaat tgctgtaaat tgccgtcgat atgcaaatcg gtttgtaagc gggcaatatc
     8521 gcggcacaga aacgccatct ctttatgggt ttctaatttt ttgcgccact tttcggcaac
     8581 cgcatccaga ttctcatata tcccttccag actctgaaac tcgaccagca gctgcgtggc
     8641 gcttttgggt ccgatccccg caacacccgg tacctttgaa ctgctgatcc ccgcaagccc
     8701 ccagtaatcg ggcaactgct gcggttgaac gccaaattct ttatcgataa atggcgcatc
     8761 cagccaacgt ttctggaagt aatcacgaat acgtaatgtc ggtgaaagta actgacagta
     8821 gcctttatct gtcgaaacaa tcgttgcctg atgcccggcc tgtgtcactt tgaccgccag
     8881 cgtggcggct aagtcatcgg cttcgttacc gctggctgac cagcacggga cgccgcgttg
     8941 ctcaaaggcg gtgcgtagtg caggcatctc gtcgtgcaac tcttccggca ttggcggtcg
     9001 acccgctttg taatctggta aacgctgatg acgccagccg ctactgcggt tttcatcatc
     9061 aaaaacggcg accgcgtggg ttggctggct gtgcataatg agctgatcga gcgcgtgctg
     9121 gcaggtttcg acacagggcg aaccctgaac ggcatgaaca cgacgaataa gattcagtgc
     9181 atcgacaata agcaaatgaa cagccacgat aaccccctta aagatcaggc gataagggta
     9241 acattcgatg ccggaacagg ctatggctgg ttgagaaaac gggaagaggc ctcgcaaaac
     9301 gaggcctccg ggagagatta atcgcaggca acgatcttca ttgccaggcc accgcgagag
     9361 gtttcgcggt acttggcgtt catatcttta cctgtttcgt acatggtctc gataacttta
     9421 tcgaggcaga cgcgcggctc gctggtacgg cgcagcgcca tacgcgcggc gttcaccgct
     9481 tttactgccg caatggcgtt acgctcgatg cacggtacct gcacctgtcc agcaaccggg
     9541 tcacacgtca gaccgaggtt atgctccatg gcgatttccg ccgcgatgca cacctgcgcc
     9601 gggcttgcgc ctaacagttc tgccagacca gctgccgcca tagagcacgc cacgccaact
     9661 tcaccctggc aacccacttc ggcaccagaa atcgacgcgt tcatcttata aagagaacca
     9721 atggcgctgg ctaccagcag gtaacgagcc agtgagttag cgttcacttc gcggataaac
     9781 ttatcgtagt acgccagcac agccgggata atcccgcacg caccgttagt cggcgcagtc
     9841 accacgcgac cgccagcagc gttctcttcg ttcactgcca gtgcaaacat gttgatccag
     9901 tcaacaaccg ccatcgggtc agtggtggtt ttatcctggc tgaccagcat ccggcgtagt
     9961 gccgcagcac ggcgtggtac gcgcagtttg ccaggcaaca cgccttcggt ggaaataccg
    10021 cgctcaatac cgccgcgcat gacttcccag acgttcgcca ggtgctgttc cagctcttct
    10081 ttgctgtgca gcgccagctc gtttttcatc atcaggccag agagtgacag cccggtttcc
    10141 tgacaatgtt tttgcagatc ggctgctgaa ctgtacggat aaggaacttc aaccggtgcg
    10201 ctatcctgct ggccaaaatg ttcttcatca acgataaagc caccgccgat agagtagtaa
    10261 gtctggctgt aaacgacttt atcgcccgcc agcgcggtaa tgcgcatacc gttttcatgc
    10321 agagaaaggt tgtcggcatg gaagttcatg cactgatcaa ccgggaactc cacttcatgc
    10381 tgaccatttg ccagcatcag gcgaccatga gtattcacat cctgaataaa accagggatg
    10441 gaatcgatat ccacggtatc cggcaggtta cccgccaggc ccataataat ggcgatatca
    10501 gtgtggtggc ctttaccagt cagagagagc gagccgtaca cgtcaaccac cacgcgggtc
    10561 acgtctttaa gcaggttacg ggcaatcaga tcgtcggtaa attgtttacc cgctttcatt
    10621 ggtccaacgg tatgagaact ggaagggcca atgccgattt tgaaaatatc gaatacgcta
    10681 atcataggaa atacatcgcg ttaaaacgga ggaagcgccg cccgaaagcg gcgcgaaagg
    10741 acttagctga acagagagta gaagattgcg gagattgcaa tcagacccat cacgacaacg
    10801 aatacgttgc tgatgtgacc gctgtactta cgcattgccg gtactttctg aattgcgtac
    10861 atcggcatca ggaacaggat catcgcgatg attgggccgc ccagggtttc aatcataccc
    10921 aggatgctcg ggttcagggt ggcaacaatc caggtcgtta ccagcatgaa cagcgcagtg
    10981 atacggttca gcttgttgat ttcgatagac ttacctttac cacgcagaga tttaatcacc
    11041 ataccgttga agccttcacg tgcgcccagg tagtggccga ggaaggattt ggtgatagcg
    11101 ataatcgcga taatcggtgc catccacgcg ataaccggtg cgttaaagtg gttagccagg
    11161 taagacagaa tcgagatgtt ctgctcttta gccgcagcca ggtctgccgg agtcaggctc
    11221 agtacgcagc tgaagacgaa gaacattacg gtcagcacca tcatgatgtg tgcgaatgca
    11281 aggatcttcg agcatttctg ttctgccata tcgccgtact cttcacgctt cgcaacggcg
    11341 aaagaagaga tgatcggaga gtggttgaac gagaacacca ttaccggaat tgccagccac
    11401 agggtcatcc acagaccgtt tccggttgcc gatgcagtgt ccagagacag cgtttccagt
    11461 gctgcgccgt tccactgcgg gatcaggtac agagccagca gcatcagtac gccaacaaac
    11521 gggaatacca gaatactcat cgctttaacg atcatctgct caccgaagcg aacgatggtc
    11581 atcataccca cgatcaggat cagcgacaga atcgcacgcg gcggtggtgt catacccagc
    11641 tggtgagaca tgaagctttc aactgtattg gtgattgcca cgctataaac cagcaggatc
    11701 gggtagatag cgaagaagta gagcagggta atcagtttac ctgcgccaat accaaagtgt
    11761 tcttctacaa cctcggtgat gtcttcgcct gggtttttac cagacagtac gaagcgagtc
    11821 aggccgcggt gagcaaaaaa tgtcatcggg aacgcaagga tagccatgat gatcagcggg
    11881 atcataccgc caacaccggc attgattggc aggaacagca cgcccgcgcc gattgccgtg
    11941 ccgtaaaggc ccagcatcca catggtgtct gtcttgcgcc aggcactacg agagtctttc
    12001 gacgcaatcg tgctggtttg agtcgtttcc atctatttct cctggaggaa tgcaaataat
    12061 tcagctttta gccagttcag cccgggaagg tgcctgaccg taaaaatgaa atctgtctat
    12121 cggcgatggc ttaatcattt accgccgtaa taatttgagg gcggaaagat acacacaagt
    12181 tatgtatcta tcagtgatct tgatcccaaa tacaataatc tacttggaag atagattatc
    12241 ccaacgcttt actctgtaaa tcaaaagtaa aagagaattt aagggcaata tttgcccatt
    12301 aaacgacatc tgacttcttc cggggcgcgc aatatatgta ggttgaactg aaaaaatcaa
    12361 tacttttagt taatcatggc gataatttct ttttcatagc gataaaatgt ggtttatgaa
    12421 aataggtaaa cgtttgcgtt acaac
//
LOCUS       DACAOP010000117        12400 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.117, whole genome shotgun sequence.
ACCESSION   DACAOP010000117 DACAOP010000000
VERSION     DACAOP010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12400
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.117"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            394..1218
                     /gene="gadX"
                     /locus_tag="IT892_003835"
     CDS             394..1218
                     /gene="gadX"
                     /locus_tag="IT892_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadX"
                     /protein_id="HAP3136990.1"
                     /translation="MQSLHGNCLIAYARHKYILTMVNGEYRYFNGGDLVFADASQIRV
                     DKCVENFVFVSRDTLSLFLPMLKEEALNLHAHKKVSSLLVHHCSRDIPVFQEVAQLSQ
                     NKNLRYAEMLRKRALIFALLSVFLEDEHFIPLLLNVLQPNMRTRVCTVINNNIAHEWT
                     LARIASELLMSPSLLKKKLREEETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGY
                     HSVSYFIYVFRNYYGMTPTEYQERSAQRLSNRDSAASIVAQGNFYGTDRSAEGIRL"
     gene            1586..2314
                     /gene="gadW"
                     /locus_tag="IT892_003836"
     CDS             1586..2314
                     /gene="gadW"
                     /locus_tag="IT892_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadW"
                     /protein_id="HAP3136991.1"
                     /translation="MTHVCSVILIRRSFDIYHEQQKISLHNESILLLEKNLADDFAFC
                     SPDTRRLDIDELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPMPLVTAIFDSFNESG
                     VNSPILSNMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAE
                     RMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYF
                     INTFRQYYGVTPHQFAQHSPGTFS"
     gene            complement(2677..5790)
                     /locus_tag="IT892_003837"
     CDS             complement(2677..5790)
                     /locus_tag="IT892_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HAP3136992.1"
                     /translation="MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTIT
                     VSATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDAAGNASITLTFETGTSPDI
                     AQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS
                     NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQ
                     LGGMPQAADQQLNASIIVQTRLQTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYS
                     TVARYNGKPAAGIAIKLAAGANALDTSRAVKEELNRLSAYFPASLKTVYPYDTTPFIE
                     ISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLS
                     AVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILKAAPEGGHKPN
                     ALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSFLPEED
                     QGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKDNVQSVFTVGGFGFSGQGQNNGL
                     AFISLKPWSERVGEENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMEL
                     LDNGNLGHEKLTQARNELLSLAAQSPNQVTGVRPNGLEDTPMFKVNVNAAKAEAMGVA
                     LSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP
                     LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYS
                     WTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLAT
                     DLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPIEAIIEAARMRLRP
                     ILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVEHL
                     FARFKKA"
     gene            complement(5815..6972)
                     /gene="mdtE"
                     /locus_tag="IT892_003838"
     CDS             complement(5815..6972)
                     /gene="mdtE"
                     /locus_tag="IT892_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtE"
                     /protein_id="HAP3136993.1"
                     /translation="MNRRRKLLIPLLFCGAMLTACDDKSAENAAAMTPEVGVVTLSPG
                     SVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELN
                     SAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAV
                     EQATINLQYANVTSPITGVSGKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQD
                     FLRMKEEVASGQIKQVQGSTPVQLNLENGKRYSQTGTLKFSDPTVDETTGSVTLRAIF
                     PNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREIE
                     ASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ"
     gene            7032..7309
                     /locus_tag="IT892_003839"
                     /pseudo
     CDS             7032..7309
                     /locus_tag="IT892_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502656.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7310..7837)
                     /gene="gadE"
                     /locus_tag="IT892_003840"
     CDS             complement(7310..7837)
                     /gene="gadE"
                     /locus_tag="IT892_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadE"
                     /protein_id="HAP3136994.1"
                     /translation="MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNKPFKVI
                     IDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKLKAKAPIYFVSRKESIKNLLEIT
                     YGKHLPHKNSQLCFSHNQFKIMQLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKL
                     RRMSDIVTLGITSYF"
     gene            complement(8636..9208)
                     /gene="hdeD"
                     /locus_tag="IT892_003841"
     CDS             complement(8636..9208)
                     /gene="hdeD"
                     /locus_tag="IT892_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-resistance protein HdeD"
                     /protein_id="HAP3136995.1"
                     /translation="MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFV
                     SGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVLSGFLVAVAYLLIGYFFIRAPEL
                     GIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIVIAWIFLGATPMVS
                     VTLVSTLVGIELIFSAASLFSFASLFVKQQ"
     gene            9463..9795
                     /gene="hdeA"
                     /locus_tag="IT892_003842"
     CDS             9463..9795
                     /gene="hdeA"
                     /locus_tag="IT892_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeA"
                     /protein_id="HAP3136996.1"
                     /translation="MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLA
                     VDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKQANFKDKVKGE
                     WDKIKKDM"
     gene            9911..10237
                     /gene="hdeB"
                     /locus_tag="IT892_003843"
     CDS             9911..10237
                     /gene="hdeB"
                     /locus_tag="IT892_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417966.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeB"
                     /protein_id="HAP3136997.1"
                     /translation="MNISSPRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFID
                     LNPKAMTPVAWWMLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQA
                     SNDLPN"
     gene            10301..10948
                     /locus_tag="IT892_003844"
     CDS             10301..10948
                     /locus_tag="IT892_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAP3136998.1"
                     /translation="MTAEFIIRLILAAIACGAIGMERQMRGKGAGLRTHVLIGMGSAL
                     FMIVSKYGFADVLSLDHVGLDPSRIAAQVVTGVGFIGAGNILVRNQNIVGLTTAADIW
                     VTAAIGMVIGSGMYELGIYGSVMTLLVLEVFHQLTFRLMNKNYHLQLTLVNGNTVSML
                     DWFKQQKIKTDLVSLQENEDHEVVAIDIQLHATTSIEDLLRLLKGMAGVKGVSIS"
     gene            complement(10990..11520)
                     /locus_tag="IT892_003845"
     CDS             complement(10990..11520)
                     /locus_tag="IT892_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP3136999.1"
                     /translation="MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVI
                     IDTLMNNVFHSNFLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTITIIDFVALI
                     NGSYCSVPEAAVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNL
                     KRINELVRHQHIDYLV"
     gene            complement(11676..12242)
                     /gene="slp"
                     /locus_tag="IT892_003846"
     CDS             complement(11676..12242)
                     /gene="slp"
                     /locus_tag="IT892_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312404.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein Slp"
                     /protein_id="HAP3137000.1"
                     /translation="MNMTKGALILSLSFLLAACSSIPQNIKGNNQPDIQKSFVAVHNQ
                     PGLYVGQQARFGGKVINVINGKTDTLLEIAVLPLDSYAKPDIEANYQGRLLARQSGFL
                     DPVNYRNHFVTILGTIQGEQPGFINKVPYNFLEVNMQGIQVWHLREVVNTTYNLWDYG
                     YGAFWPKPGWGAPYYTNAVSQVTPELVK"
BASE COUNT         3416 a         2759 c         2818 g         3407 t
ORIGIN      
        1 cagaacagct ttaaacacac ctgataacat aacgttgtaa aaaccgaatg cccagccttt
       61 aaaaaaacag ctgggcattc ggttgcttat taatcgcaat aatatattgg ctgtctattc
      121 atcgtgttga taagatatat gttatatgaa tgtttattaa atgtagcgat tacctttaat
      181 gtcacgaaaa gggattattt gcttactatt aatttccctg cgttcttaaa cacgtttttg
      241 tattataaat ccagtcatcc tgcccgtaga acatcacaca ttatcatcct gttctcccgc
      301 ttcgtttaaa tttatttatc aatcaatttg acttaagagg gcggcgtgct acattaataa
      361 acagtaatat gtttatgtaa tattaagtca actatgcaat cactacatgg gaattgtcta
      421 attgcgtatg caagacataa atatattctc accatggtta atggtgaata tcgctatttt
      481 aatggcggtg acctggtttt tgcggatgca agccaaattc gagtagataa gtgtgttgaa
      541 aattttgtat tcgtgtcaag ggacacgctt tcattatttc tcccgatgct caaggaggag
      601 gcattaaatc ttcatgcaca taaaaaagtt tcttcattac tcgttcatca ctgtagtaga
      661 gatattcctg tttttcagga agttgcgcaa ctatcgcaga ataagaatct tcgctatgca
      721 gaaatgctac gtaaaagagc attaatcttt gcgttgttat ctgtttttct tgaggatgag
      781 cactttatac cgctgcttct gaacgtttta caaccgaaca tgcgaacacg agtttgtacg
      841 gttatcaata ataatatcgc ccatgagtgg acactagccc gaatcgccag cgagctgttg
      901 atgagtccaa gtctgttaaa gaaaaaattg cgcgaagaag agacatcata ttcacagttg
      961 cttactgagt gtagaatgca acgtgctttg caacttattg ttatacatgg tttttcaatt
     1021 aagcgagttg cagtatcctg tggatatcac agcgtgtcgt atttcattta cgtctttcga
     1081 aattattatg ggatgacgcc cacagagtat caggagcgat cggcgcagag attgtcgaac
     1141 cgtgactcgg cggcaagtat tgttgcgcaa gggaattttt acggcactga ccgttctgcg
     1201 gaaggaataa gattatagag ttttactcag acataaaaaa aacccggcat aggggaccgg
     1261 gaagaggata gtctgccgtc tccagactaa taaaccgtta taacactccc tgttggcacg
     1321 ggaaactttg tgctctcagt aagttaaata taacttttac tggaaataag atcagccatt
     1381 tttttataaa cataagctat acgctgtgcg aaaatatatt cgtgctgcat ttacttatta
     1441 tcaattaact gttatgcaaa actactttgt ggataaattt tggtcctacc aaatctggca
     1501 gtttttgcgc taagaaacag tctggcatca tttcattagt atactgaaat tgaaataatc
     1561 gcagtatgaa atataaggga taatcatgac tcatgtctgc tcggtgatcc tcattcgtcg
     1621 ttcattcgat atttatcatg aacagcaaaa aatatcgctg cataacgaga gtattctgct
     1681 gctggagaaa aatttggcag acgattttgc gttttgttca ccggatacgc gacgactgga
     1741 tatcgatgag ctgacagttt gccattactt acaaaatatt cgtcagctac cacgcaattt
     1801 agggttacac agcaaagacc gtttgttaat taaccagtca ccccccatgc cgctggtgac
     1861 ggcgattttt gatagcttca atgaatccgg ggtaaattca ccgatactga gcaatatgct
     1921 ctacctttcc tgtttatcga tgttttctca taagaaagaa ctgatcccct tacttttcaa
     1981 tagcatcagc actgtttcag gaaaagttga acgccttatt agctttgata tcgccaaacg
     2041 ttggtatctg cgcgatatcg cggaaagaat gtataccagc gagagtctaa tcaaaaaaaa
     2101 gttgcaggat gaaaatacct gtttcagtaa aatattactc gcctccagga tgtcgatggc
     2161 cagacgatta ctcgagttac gtcaaattcc tctgcatact attgcggaaa aatgtggcta
     2221 tagcagtaca tcgtacttta taaacacatt tcgacaatat tatggtgtaa cgccacatca
     2281 gtttgcgcaa cattcgccag gtaccttttc ctgacatatt tcgcatttga atattggtca
     2341 ggatctcaca cctgcttcat gtgaaactct tccctgatga tttctgccgg gctaccggct
     2401 agttctcttt cgcagtttgc caggcggtat cggtattttc aggaggaaaa gactcggcat
     2461 gtttgggatt attaagctga caattcatac gattacggga atgtgggtca gtattgtgtt
     2521 gttcaaattg atgacgaatg gctggagtgg tttctacttt cagtgctgtg tactaagcct
     2581 ggtattcctg acggttagct ggttgttgag tggtgaatgg ttagcaggaa agagtaaggc
     2641 tgaaccttca tgttcaacct tactctcatt tacacgttac gcttttttaa agcgggcaaa
     2701 gagatgttcc actacaacga aaaagaccgg aacgaagtaa attgccagca ctgttgcggc
     2761 aaacatcccg cccatcacgc cggtacctac cgcgttttgc gcgccagaac cggcaccatg
     2821 actgataacc agcggcagca cgccgagaat aaaggccaga gaggtcatca ggattgggcg
     2881 taaacgcatc cgcgccgctt cgatgattgc ctctatcggc gttttccctt ctttctgcat
     2941 catctcaacg gcaaattcga caatcaggat ggcgtttttg gcggaaagcc cgatggtggt
     3001 cagcaaacca acctggaagt agacgtcatt acttaagccg cgcagatcgg tggccagtaa
     3061 tgcgccaacg acgcctaacg gaacaaccaa catcaccgag aacggaattg accagctctc
     3121 atagagtgcg gcgagggcga ggaacaccac gaccagtgaa atcgcataca gcgcaggagc
     3181 ctgatttgag gataacgctt cctgatacga tagtccggtc catgagtagc cgacgcctgc
     3241 cggaagttta gcgaccaggt ctgccataaa tttcatggcg tcaccggtac ttttcccggc
     3301 cgccgcttca cctaaaatct ccattgacgg gatgccgttg tagcgttcca gtcgcggtga
     3361 accataggtc cattcggtag acgagtaggc agaaagcggt gccatcgtgc cagaggcgtt
     3421 gcgtacatac cattggttga tgttatccgg caacatacgg aacggcgtgc ctgcctggac
     3481 atacactttt ttcacccgcc cctggttgag gaagtcgttc acgtagctgc tgccgaaggc
     3541 ggtggaaatt gtctggttga tatcagacag cgccacgccc atcgcttcag ctttcgcagc
     3601 gttgacgttc actttgaaca tcggcgtatc ttccaggccg ttcgggcgta ccccggtgac
     3661 ctgattcggt gattgcgctg ccagtgataa cagctcgttt cgcgcctggg ttagtttttc
     3721 gtgccccagg ttaccgttgt ccagcagttc catatcaaaa cctgacgcgg tacccagttc
     3781 agccaccgcg ggtaagttga acgggaagac gacggcttta ttgatactgc ttaacgcaat
     3841 cattgcccgc tgaatgatcg cggtaaccga gttttcctca ccgacacgtt cagaccacgg
     3901 cttgagactg ataaacgcca ggccgttgtt ttgcccctga ccgctgaagc caaagccgcc
     3961 aacggtaaac accgactgga cattatcttt ctctttagtc agataataat ccgtcacctg
     4021 ttgcagcact ttcgtggtgt taaccatggt ggcaccggaa ggtaactgcg cggtggtcat
     4081 aaataccccc tgatcctctt ctggtaagaa agaggtcggc gtgcgcagga acagcaccgc
     4141 catcccggcg caaatcagca ggtagaccac catgtagcga ccggtacaac gcaacagcga
     4201 gcgggtgcta tcggtatagt gttgagttga tttttcaaac agcgtgttga agcgtgcgaa
     4261 cagggcgtta ggtttgtgac cgccttccgg cgcggctttc agaatggtgg cgcacagggc
     4321 aggggtcagg ctcattgcca caaatactga aagcagcatg gaggagatca gcgtgatgga
     4381 gaactggcgg tagatctccc cggttgcacc gctcataaag gccatcggca taaacactgc
     4441 ggaaagaaca acggcaatac cgaccagcgc acgttggatc tgccccatcg atttatgcgt
     4501 cgcttccttc ggcggtagct tatcttccgc aatgacacgc tcgacgttct ccaccaccac
     4561 gatggcgtca tccaccagta accctatcgc cagcaccatc ccgaacatag tcaacgtgtt
     4621 gatggtgaaa ccgaccgccg acaagatcgc aaacgtcccg agaataacca ccggtacggc
     4681 aatcgtcggg atgattgtgg cacggaaatt ctgcaaaaac agatacatga ccaggaagac
     4741 taggatgata gcctcaacca gtgttttgaa aacttcctga atagaaattt cgataaacgg
     4801 cgtggtgtcg taaggataaa ccgtcttcag acttgccggg aaataggctg ataagcggtt
     4861 cagttcctct ttgactgccc gcgaggtatc cagggcgttt gctccggcag ccagtttgat
     4921 ggcgatcccg gcagcaggtt tgccgttata gcgcgccacg gtggaataat cttccgcccc
     4981 aagttcgacg cgagcgacat cacgcagcag cacttgcgaa ccatcttgct gaactttcaa
     5041 caggattttg ccaaattctt ccggcgtttg cagacgcgtc tgcacaatga tcgaggcgtt
     5101 tagctgctgg tctgccgcct gtggcatgcc acccagttga ccaccggaaa tctggttgtt
     5161 ttgcacctta atctgggaaa taacatcgga aggtaccagg ttatatttat tgagtttttg
     5221 cgggtccagc cagatacgca tggcatactc ggaaccaaag agttgtacgc taccaacgcc
     5281 cgcggtacgg cttagcgggt ctttgatatt agacgctaca tagtccgcga tatcgtactg
     5341 gttgaggctg ccgttatcag aaataaacgc cgctaccatc aggatattac tgctcgactt
     5401 atcgacgcta atcccctgct gctgcactgc ttcaggtaat gaaggcatag cgagttgcag
     5461 tttattttgc acttgaacct gtgcgatatc aggagatgtc ccagtctcga aggtcagagt
     5521 gatagaggca ttgcccgccg catcactggt tgaagacatg tacatcaggc catcaagccc
     5581 attcatattt tgctcaatca cctgagtgac cgagtcttct accgtttgcg catcggcacc
     5641 tggataggta gcgctgacgg taatggtcgg tggcgcaatc tgcggatact gcgcaaccgg
     5701 taagttcatg atcgccagac cacctgcaag catcataata atggcaagta cccaggcaaa
     5761 aaccgggcga tcaataaaat agttagccat gaaagtcccc ttaagcctgc aacgttattg
     5821 tttcgattcg gtgctggcgt tttcctggct ggaggaaatt gctcgtgctt tgatacccgg
     5881 acgaatgcgt tgcaaaccgg aaacgatcac ccgatcgcca gcctgcaagc cagaggtgac
     5941 gacccactgg tcgccgatgg ctttgctggc ttcaatttcg cgtagctgca cgacatcgtc
     6001 tttatccaga atgagcgccg ttgctttacc ctgggcgttg tgggtgacgc cttcctgcgg
     6061 caccagtaat acattctggc ggctaccttc atccactaat gccgtgacgt acatgccagg
     6121 cagcaagtca ccatttgggt tggggaaaat cgcccgtaac gtcacggagc ccgtggtttc
     6181 atccactgtc gggtcggaga atttcagcgt gccggtctgg ctgtagcgtt taccattttc
     6241 cagattgagc tgtactggcg tactgccctg aacctgtttg atttgcccac tggcgacctc
     6301 ttctttcatg cgtaagaaat cttgcaccga ctgcgtgaga tcgacataaa tcgggtccag
     6361 acgttgtacg gtaaccagcg aatctgcctg attagcggta acgagtgcgc cgacggtcac
     6421 cgacgatttc ccgctgacgc ccgtaatcgg cgaggtgaca ttcgcgtatt gcagattgat
     6481 cgtcgcctgt tcaacagccg ctttggcgac ggtgacattg gcttctgctt cattcaactg
     6541 ggtgcgcgcg gtgtcgtaat cctgacggct aacgtagttg gtcttcagca acgatgcctg
     6601 gcggttaaag gtgatgcggg cattgctggc ggtagagagc gctttcgcca gcgagccttt
     6661 ggcggagttt agctcggcct gtaaaggtgc aggatcaatc tgatacagcg aatcgccctg
     6721 gttcacttta tcgccttcga taaagttgcg tttaatgata ataccgccca cctggggacg
     6781 tatctcggca acttcataag gaacggttct accgggcaat tcgctcaaca cattgaccga
     6841 accgggggag agtgtgacga caccgacctc aggcgtcatg gcggcggcgt tttccgccga
     6901 tttgtcatcg caggcggtga gcatcgcgcc gcagaataac aacggtatta acagctttct
     6961 tcttctgttc attttagtcc ctgaaaattc ttgagaaata acggttcttt aaattgcgcg
     7021 cgaggagaga tatgagggat ttacagacca gcggcatagt ggggttgtca gccagtaagg
     7081 tgggatacag gcacagtgat cgacatggtg aggtcaacga caaaaaaatg ttgccgttct
     7141 gccaacagtt cctgccagca ttcgggcaac gaagggttct actggtggat acacatacca
     7201 ggggaataaa gtcgttttag cctctccttt agtaatcacc gggggtaatg aaatcagcat
     7261 ctgcatccct cgtcatgcca gccatcaatt tcagttgctt atgtcctgac taaaaataag
     7321 atgtgatacc cagggtgacg atgtcgctca tacgtcttag tttcagcttg tacataatgt
     7381 tgaatttctg aatctttaat gtttgttgcg aaatattgag cgtcgacgtg atattgcttt
     7441 catttttatt tttcagaatc agttgcataa ttttgaactg attatgtgaa aaacataatt
     7501 gtgaattctt atggggcaag tgtttaccat aagtaatctc aagaagattt ttgatacttt
     7561 ctttgcggct aacaaaataa ataggcgctt tagcttttag tttactgatg tgataaggtg
     7621 ccaaaacaat aattctctcg gcatctaatt tctccagaaa tttaatcgct tcttcatcaa
     7681 ggatatgatt gtgataggta tcaatgataa ccttgaaggg tttattgcct acttttttga
     7741 tctctgacag ggaattgatt tttatcattt cgtgattatc tttcaactgc caaaagccct
     7801 gtaaaagaaa agaatctttc gtcatgagaa aaatcataac ttgctcctta gccgttatcg
     7861 tttcgaatat gtcatccttt tcattattta catccttgtc cgaatcgttg ttcaatatag
     7921 taaacgccta taagaacttt acccttcgtg aactaatacg tctattaaca ctaatcaata
     7981 cttcagattt atccatcacg cactccatat attgatccta agtaagattc ctggttgtta
     8041 tcagcttgta aatagcaaac aaaaagttaa cgtttgcgga ttactgccca agaataagtt
     8101 atcaataacc agtttgtgat ctctgaagaa tattactaaa gttaaaatgt aatccgattt
     8161 aaatatcgag tctccttgtt tcgacttaag ctggcaattg gattgccagc tttcttttaa
     8221 cgcattgaaa ttacctgagt aaataacgca ttcatgtctt caggttttta tatagcgtct
     8281 ggagacacgg atatttatgc aatgtaatca acgccagttg caaaaaaatg aacccggatt
     8341 acttatttaa ccgcccatag catcaacgct tacggaactc tttgttcact ttcccacagc
     8401 acttttaaaa cattaaacct gactacggaa aatatcagcc atgataatgt ttgaaatggc
     8461 taatttgcca tagagtgaaa aaaattagat gaaattcagt aggttgaaat aatcactagc
     8521 aggtaattat ttcaatgata gtgcgcaatt gatctacaac actgcgtagc ggagagagta
     8581 ttaatcggat catagtcaca tcaagtgact atgatccggg tgacaaccgg ggtaattatt
     8641 gctgcttaac gaacaaactg gcgaagctga acaggctggc ggcgctaaat atcagttcaa
     8701 ttcccaccag tgtggaaacc agcgttacag acaccatcgg cgttgcacca aggaatatcc
     8761 aggcaatgac gatatccagc acaccaataa cgagctgtag ccagctgcct ttcattgaac
     8821 gctgacgata ccaactcatc aggcgaataa cccctgcaac acagaacaaa ccggcaataa
     8881 atgccgcaat ggcaaaaatg cccagctccg gtgcgcggat gaagaaatag ccgatcaata
     8941 aataggcgac tgcgacgagg aaaccggata ataccggcca gaaattatga ctgcggttgc
     9001 tgaataaccc gacaataagc gcaatacccg agcagattaa taatgcaccc actactgtgc
     9061 ttaaaatatc gccagagacg aacgggaaac tgatacacag caacccgacg ataaacagca
     9121 gcacggcaat aaactggatt gctctgcgat gttttttaag catctccaga tcaaacttca
     9181 aaattgttgc cttatctata tataacatag aaccacccta taaaattaag aagaaaatcc
     9241 cctgctatca atctatgcca aaaacgcgtc taagaatgca gtcgatttaa taaaaatttc
     9301 ctaattgcag tatctgatgc atctgtaact cattgtattg aaataaaaat atctgatttt
     9361 gatattttcc atcaacatga catatacaga aaaccaggtt ataacctcag tgtcgaaatt
     9421 gattcgtgac ggctctttca ctttatagtt gaggatatta cgatgaaaaa agtattaggc
     9481 gttattcttg gtggtctgct tcttctgcca gttgtgagca atgcagcgga tgcgcaaaaa
     9541 gcagctgata acaaaaaacc ggtcaactcc tggacctgtg aagatttcct ggctgtggac
     9601 gaatccttcc agccaactgc agttggtttt gctgaagcgc tgaacaacaa agataaacca
     9661 gaagatgcgg ttttagatgt tcagggtatt gcaaccgtaa ccccagctat cgttcaggct
     9721 tgtactcagg ataaacaagc caactttaaa gataaagtta aaggcgaatg ggacaaaatt
     9781 aagaaagata tgtaattccg ggaatgcgtt acatcgtact tccttgcata ttgaacaggc
     9841 cggaatatct tctttaaaag cagctattcc tcctgttcat atataatctc tatattgaat
     9901 gggttacaaa atgaatattt catctccccg taaagcgttt atttttatgg gcgctgtagc
     9961 ggctttgtca ctggtgaacg cacaatctgc gctggcagcc aatgaatccg ctaaagatat
    10021 gacctgccag gaatttattg atctgaatcc aaaagcaatg accccggttg catggtggat
    10081 gctgcatgaa gaaacagtat ataaaggtgg cgataccgtt actttaaatg aaaccgatct
    10141 cactcaaatt cctaaagtga tcgaatactg taagaaaaac ccgcagaaaa atttgtatac
    10201 cttcaaaaat caagcatcta atgacttgcc gaattaatga ggtgcaagta aaaaggagta
    10261 gcaagttgag ccatcttgct gctccttttt gcatttttat atgacagcag aatttattat
    10321 acgtcttata ctcgcggcaa ttgcctgtgg cgctattggc atggaaaggc aaatgcgcgg
    10381 caaaggagca gggttacgca cacatgtatt aattggcatg ggaagcgccc tgtttatgat
    10441 tgtttcgaaa tatggttttg ctgacgtgct gtctttagat cacgtcggac tcgaccccag
    10501 ccgtattgct gctcaggtgg tgacgggcgt cgggtttatc ggtgcaggta acattctcgt
    10561 tcgtaaccaa aatattgtag gtctgacgac ggcagcggat atctgggtga ccgccgccat
    10621 aggtatggtt attggcagcg gtatgtacga actgggtatt tatggttcag tgatgacctt
    10681 gttggtgctg gaagtcttcc atcaattaac cttccgcctg atgaacaaaa attaccattt
    10741 acagctgaca ttagtgaacg gtaatacggt atcaatgctc gactggttta agcagcaaaa
    10801 aataaaaact gatttagttt cgttgcagga aaatgaagat catgaagtgg tcgccattga
    10861 tatccagctt catgccacaa cgtcgataga agacctgttg cgattattaa aaggtatggc
    10921 aggggtgaaa ggcgtttcaa ttagctaatc tgtgtggcag cgtagccaga ctcaccgtaa
    10981 gcctgaaatt cacaccagat aatcaatatg ctgatggcgt accagctcat tgatccgctt
    11041 aagattgagg atcatcatga tattgtgttt atggcagtag aacgttttta gcgatatttt
    11101 cagtttctcc agaatatctt ccgttgtcat ttgattcgca atgcagctca gaacctgatg
    11161 ttgcttgcgc gaaagtgaca cagccgcttc aggcacagag cagtaactgc cattgatgag
    11221 tgcgacaaaa tcaatgatag tgatagtccg cggaacaaag gtcaccggca ctttccccag
    11281 gcagcgttta atattaaagg gggagaaaat aatgacatgg acaggtttta atcgttcaat
    11341 ttgagtgaga aaattagaat gaaatacatt attcattaat gtatcaataa tgacgaaggc
    11401 attctgatgc aacattacgt cgatctcttc ttcgttctgt atatgaacga cattaccttt
    11461 actcagaatg tttttcatcg cggtgaagaa catcgtatcc ctggtaatta taagaaacat
    11521 aaccgactcc tggtgcggac attaacttta taatcagttt gccaaaggta attaacagga
    11581 cagggcttat aataataata gttagcttac tgtgtattaa tttgatgtaa tgcatgatgc
    11641 agatgctgag aaagcatctg catctttcgg tggtgttatt tgaccagctc aggtgttacc
    11701 tgactcaccg cattggtgta gtaaggcgca ccccagcccg gtttcggcca gaatgcacca
    11761 tagccgtaat cccacaggtt ataggtggta ttaaccactt ctctcaaatg ccacacctgg
    11821 atgccctgca tattcacttc caggaagtta tacgggactt tattgataaa gccaggttgt
    11881 tcaccctgaa tggtgccgag gatggtaaca aagtgattac gatagttcac tggatcaagg
    11941 aagccgcttt gtctggcgag cagtcggccc tgatagttgg cttcaatatc aggcttcgca
    12001 tagctatcca acggtaatac agcgatttct aacaacgtat ccgttttgcc attgataacg
    12061 ttgataacct tcccaccaaa gcgcgcttgt tgaccaacat ataaccccgg ctggttatga
    12121 acagcaacaa aacttttttg aatatcaggt tggttattgc ctttgatatt ttgcggaatt
    12181 gaactacatg cggcaagcaa aaatgaaagg ctgaggatga gtgcaccttt tgtcatgttc
    12241 atgttactat ccttatcaac aaatattaaa accataatag atatttcttt atagttttca
    12301 tctgattctg aggtgatatg cctgatagta acgtaaacct gtctgatgtt tatatccttt
    12361 ctgtttaggt gaactcagtt aattttgggg cgtgacatga
//
LOCUS       DACAOP010000118        12083 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.118, whole genome shotgun sequence.
ACCESSION   DACAOP010000118 DACAOP010000000
VERSION     DACAOP010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12083
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.118"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..47
                     /locus_tag="IT892_003847"
     CDS             <1..47
                     /locus_tag="IT892_003847"
                     /inference="COORDINATES: protein motif:HMM:NF025322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HAP3137001.1"
                     /translation="IIIVVLLVISFPAY"
     gene            320..379
                     /gene="ibsA"
                     /locus_tag="IT892_003848"
     CDS             320..379
                     /gene="ibsA"
                     /locus_tag="IT892_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsA"
                     /protein_id="HAP3137002.1"
                     /translation="MMKHVIILVILLVISFQAY"
     gene            601..1260
                     /locus_tag="IT892_003849"
     CDS             601..1260
                     /locus_tag="IT892_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP3137003.1"
                     /translation="MSEQIKFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAEL
                     VTFRDELLADSLALKRVELGIVTFGPVHVEQPFTSAANFFPPILFAHGDTPMGAAITK
                     ALNMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFQGEEDKKFAFFSIG
                     VQGADMKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTS
                     V"
     gene            1257..2018
                     /gene="pphC"
                     /locus_tag="IT892_003850"
     CDS             1257..2018
                     /gene="pphC"
                     /locus_tag="IT892_003850"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase PphC"
                     /protein_id="HAP3137004.1"
                     /translation="MSWRLVYASAVGTSHISADLSCQDACQMQVAWLEDQQPLLSVFV
                     ADGAGSVSQGGEGAMLAVNEAMAYMSQKVQGGELGLNDVLATDIVLTIRQRLFAEAEA
                     KELAVRDFACTFLGLISSANGTLIMQIGDGGVVVDLGHGLQLPLTPMVGEYANMTHFI
                     TDDDAVSRLETYTSTERAHKVAAFTDGIQRLALNMLDNSPHVPFFTPFFNGLASATQE
                     QLDLLPELLKQFLSSPAVNERTDDDKTLALALWLP"
     gene            2015..3955
                     /gene="yegI"
                     /locus_tag="IT892_003851"
     CDS             2015..3955
                     /gene="yegI"
                     /locus_tag="IT892_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310906.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YegI"
                     /protein_id="HAP3137005.1"
                     /translation="MKPTLYTATGECVTPGRELGKGGEGAVYDIEEFVDSVAKIYHTP
                     PPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRGGKVIGFMMPKVSGKEPIHMIYS
                     PAHRRQSYPHCAWDFLLYVARNIASSFATIHEHGHVVGDVNQNSFMVGRDSKVVLIDS
                     DSFQINANGTLHLCEVGVSHFTPPELQTLSSFIGFERTENHDNFGLALLIFHVLFGGR
                     HPYSGVPLISDAGNALETDIAHFRYAYASDNQRRGLTPPPRSIPLSMLPGDVEAMFQQ
                     AFTESGVATGRPTAKAWVAALDLLRQQLKKCTVSAMHIYPGHLTDCPWCALDNQGVIY
                     FIDLGEEVITTSGDFVLAKVWAMVMASVAPPALQLPLPDHFQPTGRPLPLGLLRREYI
                     ILIEIALSALSLLLCGLQVEPRYIILVPVLAAIWIIDSLTSKAYKAEVQRRREAFNRA
                     KMDYDHLVSQIQQLGGLEGFIAKRTMLEKMKDEILGLPEEEKRALAALQDNARERQKQ
                     KFLEGFFIDAASIPGVGPARKAALRSFGIETAADVTRRSVKQVKGFGDHLTQAVIDWK
                     ASCERRFVFRPNEAVTPADRQAVMAKMAAKRHRLESALTVGATELQRFRLHAPARTMP
                     LMEPLRQAAEKLAQAQADLSRC"
     gene            complement(3968..5320)
                     /gene="yegD"
                     /locus_tag="IT892_003852"
     CDS             complement(3968..5320)
                     /gene="yegD"
                     /locus_tag="IT892_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416573.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HAP3137006.1"
                     /translation="MFIGFDYGTANCSVAVMRDGKPQLLKMENDSTLLPSMLCAPTRE
                     AVSEWLYRHHDVPVDDNETQALLRRAIRYNREEDIDVTAKSVQFGLSSLAQYIDDPEE
                     VWFVKSPKSFLGASGLKPQQVALFEDLVCAMMLHIRQQAQAQLPDAITQAVIGRPINF
                     QGLGGDEANTQAQGILERAAKRAGFKDVVFQYEPVAAGLDYEATLQEEKRVLVVDIGG
                     GTTDCSLLLMGPQWRSRLDREASLLGHSGCRIGGNDLDIALAFKNLMPLLGMGGETEK
                     GIALPILPWWNAVAINDVPAQSDFYSSANGRLLNYLVRDAREPEKVALLQKVWRQRLS
                     YRLVRSAEESKIALSSVAETRASLPFISDELATLISQQGLESALNQPLARILEQVQLA
                     LDNAQEKPDVIYLTGGSARSPLIKKALTEQLPGIPIAGGDDFGSVTAGLARWAEVVFR
                     "
     gene            5454..6311
                     /gene="alkA"
                     /locus_tag="IT892_003853"
     CDS             5454..6311
                     /gene="alkA"
                     /locus_tag="IT892_003853"
                     /EC_number="3.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2"
                     /protein_id="HAP3137007.1"
                     /translation="MYTLNWQPPYDWSWMLGFLAARAVNGVETVADDYYARSLAVGEY
                     RGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGKLGAAR
                     PGLRLPGSVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPDYVCFPTPQR
                     LAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRW
                     TANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEG
                     WQPDGTDEL"
     gene            complement(6349..9666)
                     /locus_tag="IT892_003854"
     CDS             complement(6349..9666)
                     /locus_tag="IT892_003854"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HAP3137008.1"
                     /translation="MSKQSQHVLIALPHPLLHLVSLGLVSFIFTLFSLELSQFGTQLA
                     PLWFPTSIMMVAFYRHAGRMWPGIALSCSLGNIAASILLFSTSSLNMTWTTINIVEAV
                     VGAVLLRKMLPWYNPLQNLADWLRLALGSAIVPPLLGGVLVILLTPGDDPLRAFLIWV
                     LSESIGALALVPLGLLFKPHYLLRHRNPRLLFESLLTLAITLTLSWLSMLYLPWPFTF
                     IIVLLMWSAVRLPRMEAFLIFLTTVMMVSLMMAADPSLLATPRTYLMSHMPWLPFLLI
                     LLPANIMTMVMYAFRAERKHISESETRFRNAMEYSAIGMALVGTEGQWLQSNKALCQF
                     LGYSQEELRGLTFQQLTWPEDLNKDLQQVEKLISGEINTYSMEKRYYNRNGDVVWALL
                     AVSLVRHTDGTPLYFIAQIEDINELKRTEQVNQQLMERITLANEAGGIGIWEWELKPN
                     IFSWDKRMFELYEIPPHIKPNWQVWYECVLPEDRQHAEKVIRDSLQSRSPFKLEFRIA
                     VKDGIRHIRALANRELNKEGEVERLLGINMDMTEVKQLNEALFQEKERLHITLDSIGE
                     AVVCIDMAMKITFMNPVAEKMSGWTQEEALGVPLLTVLHITFGDNGPLMENIYSADTS
                     RSAIEQDVVLHCRSGGSYDVHYSITPLSTLDGSNIGSVLVIQDVTESRKMLRQLSYSA
                     SHDALTHLANRASFEKQLRILLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALL
                     RELASLMLSMLRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAVNDYHFIWEGR
                     VHRVGASAGITLIDDNNHQAAEVMSQADIACYASKNGGQGRVTVYEPQQAAAHSERAV
                     MSLDEQWRMIKENQLMMIAHGVASPRIPQARNLWLISLKLWSCEGEIIDEQTFRRSFS
                     DPALSHALDRRVFHDFFQQAAKAVASKGLSIALPLSVAGLSSTTLVNELLEQLENSPL
                     PPRLLHLIIPADAILDHAESVQKLRLAGCRIVFSQVGRDLQIFNSLKVNMADYLLLDG
                     ELCANVQGNLMDEMLITIIQGHAQRLGMKTIAGPVVLPLVMDTLPGIGVDLIYGDVIA
                     DAQPLDLLVNSSYFAIN"
     gene            9984..10625
                     /gene="udk"
                     /locus_tag="IT892_003855"
     CDS             9984..10625
                     /gene="udk"
                     /locus_tag="IT892_003855"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAP3137009.1"
                     /translation="MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVI
                     PEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTR
                     MKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
                     MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE"
     gene            10717..11298
                     /gene="dcd"
                     /locus_tag="IT892_003856"
     CDS             10717..11298
                     /gene="dcd"
                     /locus_tag="IT892_003856"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HAP3137010.1"
                     /translation="MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTF
                     RGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFNLHPGELALAVTLESVTLPAD
                     LVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
                     EPLSGPAARPYNRREDAKYRNQQGAVASRIDKD"
     gene            11320..>12083
                     /gene="asmA"
                     /locus_tag="IT892_003857"
     CDS             11320..>12083
                     /gene="asmA"
                     /locus_tag="IT892_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HAP3137011.1"
                     /translation="MRRFLTTLMILLVVLVAGLSALVLLVNPNDFRDYMVKQVAARSG
                     YQLQLDGPLRWHVWPQLSILSGRMSLTAQGASQPLVRAYNMRLDVALLPLLSHQLSVK
                     QVMLKGAVIQLTPQTEAVRSEDAPVAPRGNTLPDLSDDRGWPFDISSLKVADSVLVFQ
                     HEDDEQVTIRNIRLQMEQDPQHRGSFEFSGRVNRDQRDLTISLNGTVDASDYPHDLMA
                     AIEQINWQLQGADLPKQGIQGQGSFQVQWQESHKRLS"
BASE COUNT         2843 a         3099 c         3231 g         2910 t
ORIGIN      
        1 ggatcatcat cgtggtgctc ttagtcataa gcttcccggc ttactaagac taccagggcg
       61 ggggaaaccc cgctctaccc tcactcctga aattatgcct tcacgataag attgtcaatc
      121 cgcaggcttt gtagtctgcg atcctgccag caaatattct ttgcgagtcg ttacgcaata
      181 atcacagagg aaactatttt gttcacgcgt tagcgataga ctgcattcag ggcgaaagga
      241 ggtaagccga cgatttcagc gggacgctga aacgggaaac cctctcccgg agaagagggc
      301 ttttaataag gaaagggtta tgatgaagca cgtcatcata ctggtgatac tcttagtgat
      361 tagcttccag gcttactaag aacaccaggg ggagggggga aacctctccc taaccctcac
      421 tcctgaaatt atgtcactcc gcccttagtg tcaatcgacg gctctccgtt cttgcgaggc
      481 gaatagcaaa attttctgcg ccgccgggcc taattctgaa agtttcttcg tttgctctta
      541 tttcattatt gcaatcggta tgataccgga cctcaataat tctctaagaa aggatttctt
      601 atgagcgaac aaatcaagtt tgccaccagc gattttgcca gtaacccgga accacgttgc
      661 ccctgcattt tgctgctgga tgtttctggt tctatgaacg gtagacctat taatgaactt
      721 aacgccgaat tggttacctt tcgcgatgag ctgcttgccg attcgctggc cttaaaaaga
      781 gtggaactcg gtattgtgac gttcggcccg gtgcatgtgg aacaaccatt taccagtgcc
      841 gctaattttt tcccgcccat cctgtttgcc catggggata caccaatggg cgccgccatt
      901 accaaagccc tgaatatggt tgaggagcgc aaacgtgagt atcgcgccaa tggtatttcg
      961 tattatcgtc cgtggatttt cctgattacc gatggcgcac caaccgatga gtggcaggct
     1021 gctgccaaca aggtgtttca gggggaagaa gataagaagt ttgccttctt ttccatcggt
     1081 gttcaggggg cggatatgaa gacgctggcc caaatcagcg ttcgtcagcc tttgcctctt
     1141 caaggattac aattccgcga actatttagc tggttatcca gttcgctgcg ttcggtttcc
     1201 cgctccacgc cgggaacgga agttgtgctg gaagcgccaa aaggctggac gtcagtgtga
     1261 gctggcgtct ggtttatgca tcagccgttg gaacgtcgca catcagcgct gacttgtctt
     1321 gccaggatgc ctgccagatg caggttgcct ggttagaaga ccagcagcca ttattgtcgg
     1381 tatttgtcgc tgatggcgca ggcagcgtct cgcagggtgg cgaaggtgcg atgctcgccg
     1441 tcaatgaagc gatggcttat atgtcgcaaa aagtgcaggg cggggaattg gggcttaatg
     1501 atgtcctcgc aacggacatt gtgctgacca ttcgtcagcg actttttgcc gaggcggaag
     1561 ccaaagaatt agcggttcgc gattttgcct gcacgttttt gggattgatt tcatcagcta
     1621 atggcacctt gattatgcag attggcgatg gcggcgtggt ggtagatttg gggcacggtt
     1681 tgcaactgcc gctcacgccg atggtggggg aatatgccaa tatgacgcac ttcattaccg
     1741 atgacgatgc tgtttccaga ctggaaactt acaccagtac tgagcgtgcg cataaagttg
     1801 cagcatttac ggatggtatt cagcgactgg cgttaaatat gctggataat tctccgcatg
     1861 tgcctttctt taccccgttt ttcaatggac tggcgtcagc aacgcaggaa caactcgatt
     1921 tattacctga attgttaaag cagtttttgt ccagtccggc ggtaaacgag cgtaccgatg
     1981 atgataaaac gttggcactg gcgctgtggt taccatgaaa cccactttat atactgctac
     2041 tggtgagtgc gttacgcctg gccgtgaact gggcaaaggc ggcgaaggtg cggtttatga
     2101 tatcgaggag tttgtcgata gcgtcgccaa gatttatcac acgccgccac ccgccttaaa
     2161 acaggacaaa cttgccttta tggctgcgac agctgacgcg caattgttga attatgtcgc
     2221 ctggccgcag gcaacgcttc acggtggacg aggcggaaag gttatcggtt ttatgatgcc
     2281 aaaagtttct ggtaaagaac cgattcatat gatctatagc ccggcacatc gtcgccagag
     2341 ttaccctcat tgtgcgtggg attttctact ctatgttgcg cgcaatattg cttcatcttt
     2401 tgctacgatt cacgagcacg ggcacgtcgt gggtgacgta aaccagaaca gctttatggt
     2461 aggtcgcgac agcaaagtgg tgttgattga tagcgactcc tttcagatta acgccaatgg
     2521 cacgctgcat ttatgcgaag tcggcgtgtc gcattttacg ccgccagagc tacaaacctt
     2581 gtcgtcattt atcggctttg aacgcacaga aaatcacgat aattttggcc ttgcgttgct
     2641 gatttttcac gtcttgtttg gtgggcggca tccttattct ggtgtgccgc ttatctctga
     2701 tgcggggaat gcactggaga cggatattgc ccatttccgt tatgcctacg cgtcagataa
     2761 tcagcgacgt ggtttaacac cgccgccacg atctattccg ctgtcgatgt taccgggtga
     2821 tgttgaagcc atgtttcagc aggcattcac ggaaagtggc gtggcaaccg ggcgtccgac
     2881 ggcaaaagcg tgggtagcgg cacttgattt actacgccaa cagttaaaga aatgtaccgt
     2941 ttcggcaatg catatttacc ccggtcattt gaccgactgc ccgtggtgtg cgctggataa
     3001 tcaaggcgtt atctatttta ttgatctcgg cgaagaggtc attaccacca gcggtgattt
     3061 tgtgctggcg aaagtctggg cgatggtgat ggcgtcagta gcaccgccag cattgcaatt
     3121 gccattaccc gatcatttcc aaccgactgg caggccgctt cctttaggcc tgttacggcg
     3181 tgaatacatc attctgattg agatcgcact gtcagcgtta tcgctgctgc tttgcggcct
     3241 tcaggtagaa ccgcgttata tcattttggt tcccgtgctg gcggctatct ggattattga
     3301 cagccttaca agcaaagcgt acaaagcaga agtccagcga cgaagagagg cttttaatcg
     3361 cgcaaaaatg gactatgacc atttagtcag ccagatccaa cagttgggcg ggctggaagg
     3421 ttttatcgcc aaacggacga tgctcgaaaa aatgaaggac gaaattcttg ggttaccgga
     3481 agaggagaaa cgcgctctgg cagcacttca ggacaacgca agggaacggc agaagcagaa
     3541 gtttctggag ggatttttta tcgatgctgc ctctattccc ggcgtaggcc cagcgcgtaa
     3601 agcggcgtta cggtcttttg gtattgaaac cgccgcagac gttacccgac ggagcgttaa
     3661 gcaagtaaaa ggttttggtg atcatctgac ccaggcggtt atcgactgga aagcgagttg
     3721 cgaacgccgt tttgttttca ggccgaacga agcggtaacg cctgcagaca gacaagcggt
     3781 aatggcaaaa atggccgcca aacgacatcg gctggaatcg gcgctgactg tcggtgcgac
     3841 agagttgcag cgattccgcc ttcatgctcc agcacggacc atgccgttga tggaaccgct
     3901 acgtcaggcg gcagaaaaac tggctcaggc gcaggctgat ttaagccgtt gctgagccag
     3961 ttttcaatta acgaaacacc acttccgccc agcgtgccag cccggcggtg acggagccaa
     4021 agtcatcgcc acctgcaatc ggaatgcccg gcaactgttc tgtcagcgct tttttaatca
     4081 gcggtgaacg ggcgctaccg ccggtcagat agataacatc cggtttttcc tgggcgttat
     4141 ccagcgccag ttgcacctgt tccagaatcc gcgccagtgg ctggttgagg gcgctttcca
     4201 gcccttgctg gctaatcagc gtagccagtt catcgctgat aaacggcagt gaggcgcggg
     4261 tttccgctac gcttgaaagc gcaattttgc tctcttctgc gctacgtacc aggcgatagc
     4321 ttaaacgctg acgccagact ttctgtaaca gggccacttt ttccggttcg cgggcatcgc
     4381 gtaccagata gttaagcaga cgaccgttgg cactactgta gaaatcactt tgcgcaggta
     4441 cgtcgttgat ggcaaccgca ttccaccacg gcagaatcgg cagggcgatg cctttttcgg
     4501 tttcgccacc catgcccagt aacggcatca ggtttttaaa cgccagcgcg atatccagat
     4561 cgttaccgcc aatacggcaa ccactgtgac ccagcaggct ggcttcacga tcgagacgcg
     4621 aacgccactg cggccccatc agcagcaatg aacagtcagt cgtaccaccg ccgatatcca
     4681 ccaccagcac ccgtttttct tcctgcaagg tggcttcgta atccagccca gccgcgaccg
     4741 gctcgtactg gaataccaca tccttaaacc cggcacgctt tgccgcgcgt tccagaatcc
     4801 cttgcgcctg ggtgtttgct tcatcgccgc ccagcccctg gaagttgatc gggcgaccaa
     4861 tcaccgcctg agtaatcgca tccggcagct gcgcctgcgc ctgctggcga atatgcaaca
     4921 tcattgcgca gaccagatcc tcaaacagcg ctacctgctg cggttttaag ccgctggcac
     4981 cgaggaatga ttttggtgat ttcacaaacc acacctcttc tggatcatca atgtactgtg
     5041 ccagtgagga aagaccgaac tgcacgcttt tcgccgtaac atcgatatct tcttcgcggt
     5101 tataacgaat cgcccgacgc aacagcgcct gcgtttcatt gtcgtctacc ggaacatcat
     5161 gatggcggta cagccattcg cttaccgctt cacgcgttgg cgcgcaaagc attgaaggca
     5221 gcagcgtgct gtcgttttcc attttcagta attgtggctt accgtcgcgc atgaccgcca
     5281 ctgaacagtt tgctgtaccg taatcaaaac caataaacac gaaataatcc ccatgccggt
     5341 gaagaagggg cgtgacttta gcgaaatgtt gccgtcgcga caaccggaat atgaaagcaa
     5401 agcgtagcgt ctgaataacg tttatgctga aagcggatta acaaggagat gcgatgtata
     5461 ccctgaactg gcagccgcca tatgactggt cgtggatgtt gggatttctc gccgcccgtg
     5521 cggtgaacgg tgtggaaacg gtcgctgacg attattatgc ccgtagtctg gcggtgggcg
     5581 aatatcgcgg cgtggtgact gctattccgg atatagcccg ccatactctg cacataaatt
     5641 taagtgcagg tttagaacct gttgccgcag agtgtctggc gaaaatgagc cgcctgtttg
     5701 atctgcaatg taacccgcag attgttaacg gtgcgttggg caagttaggc gcggcgcggc
     5761 ccggattgcg tttacccggc agtgttgatg cttttgagca gggcgtgcgg gcgattttag
     5821 gccaactggt gagcgtggcg atggcggcaa aattgaccgc cagagtggca cagctttatg
     5881 gcgaacggct ggatgatttt ccggattatg tctgcttccc cacgcctcag cggctggcag
     5941 cagcagatcc gcaggcatta aaagcgttag gtatgccgtt gaaacgggca gaggcgctga
     6001 ttcatctggc aaatgcggcg ctggagggca ccttaccaat gacaataccg ggcgatgtgg
     6061 agcaggcgat gaaaacgctg caaacttttc cgggtatcgg gcgctggacg gcgaattatt
     6121 tcgccttgcg cggctggcag gcgaaagatg ttttcctgcc ggatgattat ctgattaaac
     6181 agcgatttcc gggaatgaca ccggcacaaa tccgccgtta tgccgaacgc tggaagccct
     6241 ggcgttctta tgcgctgttg catatctggt atacggaagg ctggcaacca gacggaacgg
     6301 acgaattgta ggcctgatac gccgcatcag gcgatgggga agcacgcctt agttaatcgc
     6361 gaaataactg ctattcacca gcaaatccag cggttgggca tcggcaatca catcaccata
     6421 aatcaaatcg acgccgatgc caggaagcgt atccatcacc aggggtaaaa ctactggccc
     6481 ggcgatggtc ttcatcccga gccgctgagc gtgcccctga atgatcgtaa tcagcatctc
     6541 atccatcaaa tttccctgca cgttggcgca taactcacca tcaagtagta ggtaatctgc
     6601 catatttact ttcagcgagt tgaagatttg cagatcgcgg cccacctgac tgaatacgat
     6661 ccgacatccc gccagccgca gtttttgcac gctttctgcg tgatctaaaa tcgcgtctgc
     6721 cggaataatc agatgtaata accgtggtgg taaagggctg ttttccagct gttcaagcag
     6781 ttcatttacc agtgtggtgc tactcaaacc ggcaacggaa agggggaggg cgatgcttaa
     6841 gcctttactg gcaaccgctt ttgcggcctg ctggaaaaaa tcgtggaata cccgtcggtc
     6901 aagagcatgg ctaagtgccg gatcgctgaa gctacgtcga aatgtttgtt catcaataat
     6961 ctcgccttcg caactccaga gcttaagtga aatcagccac aaattacgcg cttgcgggat
     7021 ccgcggcgaa gcgacaccgt gggcgatcat catcaactga ttctctttaa tcatccgcca
     7081 ctgttcatca agcgacatca ccgcccgttc gctatgtgcg gcagcttgct gcggttcgta
     7141 aaccgtcacc cggccctgtc caccattttt ggaggcataa caggcgatat cagcctgcga
     7201 catcacttca gccgcctgat gattgttgtc atcaatcaag gtaatcccgg cactggcacc
     7261 tacccgatgt acacgtcctt cccagataaa gtgatagtca tttacggcgc tgataatgcg
     7321 tgtagcgata aaacgcgcac tttcgacatt acaatctggc agcagcagac caaattcatc
     7381 gccaccgagt cgcgccagca cgtcgctgga gcgcagcata ctcagcatca atgacgcaag
     7441 ttcgcgcaac aaagcgtcgc cagcggcgtg cccggcgctg tcattcaccg ctttaaagcg
     7501 atcaagatcg ataaacacca gtgcatgtcg ctgatgtgta ctgtttaccg tttgcagcag
     7561 gatgcgtagt tgcttctcaa aactggcgcg attggcgaga tgcgtcagtg catcatggga
     7621 ggcgctgtag ctcagctggc gcagcatttt gcgcgattcg gtgacgtcct gaatcaccag
     7681 aaccgaacca atattgctgc cgtccagagt acttaacggc gtaatactgt aatgcacgtc
     7741 gtagctgccg ccgcttcggc agtgcaacac cacatcttgt tcaatcgcgg aacgtgaggt
     7801 gtcggcactg taaatgttct ccattaatgg tccgttgtcg ccaaaagtaa tatgcaacac
     7861 cgtcaggagt ggaacaccta acgcttcttc ctgcgtccag ccgctcatct tctccgccac
     7921 cggattcata aaggtaattt tcatcgccat atcaatacag accacggctt caccgatgga
     7981 atcaagcgta atgtgcaggc gctctttttc ctgaaacaat gcctcgttaa gctgtttaac
     8041 ctcggtcata tccatattaa tgccgagcag acgttcgact tcgccttctt tattcagttc
     8101 ccggttggcg agggcgcgga tatggcggat gccatctttc acggcaatgc gaaattccag
     8161 tttaaaggga gagcgcgatt gcaatgaatc gcgaatcact ttttcggcgt gctggcgatc
     8221 ttccggcagc acgcactcgt accacacctg ccagtttggt ttgatatgcg gaggaatttc
     8281 atacagctcg aacatccgct tatcccagct aaaaatattc ggcttaagct cccactccca
     8341 gatgccaatc ccgcccgctt cgttagccag cgtgatgcgc tccatcagtt gctgattcac
     8401 ctgttcggtg cgttttagct cgttaatgtc ttcaatctga gcgataaaat agagcggcgt
     8461 accatcggtg tggcgcacca gtgagacggc aagcaacgcc cagacaacat cgccattgcg
     8521 gttgtagtag cgtttttcca ttgaataggt gtttatttca ccgctgatca gcttttcaac
     8581 ctgttgcaga tctttattga gatcctccgg ccaggtcagt tgctgaaagg tgagtccgcg
     8641 cagttcttcc tgactgtaac cgagaaactg gcagagcgct ttgttggatt gcagccattg
     8701 cccctcggtg cccactaatg ccatgccgat ggcggaatat tccatcgcgt tccgaaagcg
     8761 ggtttcgctt tcggaaatgt gtttgcgttc cgcacgaaag gcatacatca ccatggtcat
     8821 gatgttggcg ggcagcagga tcagcaaaaa cggtagccac ggcatatggc tcatcaggta
     8881 tgtacgcggc gtagcaagca gggagggatc cgcggccatc atcagtgaca ccatcatcac
     8941 cgtggtaagg aagatcaaaa aggcttccat tcgtggcagg cgcacggcgc tccacatcaa
     9001 cagcacaata atgaaagtaa aaggccacgg cagatacagc atcgaaagcc agcttaacgt
     9061 cagtgtgatg gctaacgtga gcagcgactc aaaaagcaac cgtgggttgc gatggcgcag
     9121 cagatagtgt ggtttaaata acaatcccag cggcaccagt gccagtgcgc cgatggattc
     9181 tgacagtacc catatcaaaa atgccctgag aggatcgtct ccgggcgtca gcaggataac
     9241 cagaacaccc cctaacagag gtggaacaat ggcgctgccg agtgccagac gcagccagtc
     9301 agccagattt tgcaatgggt tataccacgg cagcatttta cgcagtagca ctgccccgac
     9361 cacggcttca acaatattga tggtcgtcca ggtcatgttc agcgagctgg tggaaaaaag
     9421 caggatggat gcggcgatat ttcccagcga gcagctcagc gcaatccccg gccacatgcg
     9481 cccggcatgg cgataaaacg ccaccatcat gatggacgtc gggaaccaca gtggggcgag
     9541 ttgggtgcca aactgcgaaa gctcaagcga gaaaagggta aagataaacg agactaaacc
     9601 taaactgacc aggtgaagca gcgggtgggg cagggcaatt aatacatgct gtgattgttt
     9661 gctcattacc gctttatccg caagaccagg tcgccagtat tcgtttctgt gtttatgcta
     9721 gtacaaaagt tttacatttt atatgcgaat tgctcataaa gtgacgtaaa ggcggataat
     9781 ttgcgcaacg gcgtataaca ttttttacct tgtataaaac tgatcaacgt aatttgccac
     9841 cgggaattct tcgtcaacaa ttaactctga gcgcgcggca acgctattcg actggtatca
     9901 ggcggatgaa atccctataa ttgccgcgtt tggcgcttcg tcgccccctt cctaacatcc
     9961 aggttaatca ggtcgctaaa tatatgactg atcagtctca tcagtgcgtc attatcggta
    10021 tcgctggcgc atcggcttcc ggcaagagtc ttattgccag taccctttat cgtgaattac
    10081 gtgagcaagt cggtgatgaa cacatcggcg taattcccga agactgctat tacaaagatc
    10141 aaagccatct gtcgatggaa gaacgcgtta agaccaacta cgaccatccc agcgcgatgg
    10201 atcacagcct gctgcttgag catttacaag cattgaaacg cggctcggcc attgacctgc
    10261 cggtttacag ctatgttgaa catacgcgta tgaaagaaac ggtgacagtt gagccgaaga
    10321 aagtcatcat tctcgaaggc attttgctgc tgacggatgc gcgtttgcgt gacgaactta
    10381 acttctcaat tttcgttgat accccgctgg atatctgcct gatgcgccgc atcaagcgtg
    10441 acgttaacga gcgtgggcgt tcaatggatt cagtgatggc gcaatatcaa aaaaccgtgc
    10501 gcccgatgtt cctgcaattc attgagcctt ctaaacaata tgcggacatt atcgtgccgc
    10561 gcggcgggaa aaaccgcatc gccatcgata tattgaaagc gaaaataagt cagttctttg
    10621 aataagcttg ataaattgtg taccgttcag tgataacctg gtatgccctt gacgtaattg
    10681 gcgttaaggg agtgatgcgc gaaaggagaa aatgccatgc gtctgtgtga ccgagatatt
    10741 gaagcctggc ttgatgaagg ccgtttgtcg atcaacccac gtccgccagt ggagcgtatt
    10801 aacggcgcga cggtggatgt gcgcctgggc aataaatttc gtaccttccg tggtcacacg
    10861 gcagcgttta tcgatctgag cggtcccaaa gatgaagtga gcgccgcgct tgaccgcgtg
    10921 atgagcgatg aaatcgtgct cgacgagggc gaggcgttta atcttcaccc aggagagctg
    10981 gcgctggcgg tgacgctgga gtcggtgacg ctgccagccg atctggtggg ctggctggac
    11041 gggcgttctt cactggcgcg tctggggctg atggtgcacg tcaccgcgca ccgtatcgat
    11101 ccgggctggt ctggctgcat tgtgctggag ttttacaact ccggtaagct gccgctggcg
    11161 ctgcgtccgg gcatgttaat tggtgcgctg agctttgagc cgctctccgg cccggcggcg
    11221 cgaccttaca accgccgtga agatgcgaaa tatcgcaacc agcagggcgc ggtagccagc
    11281 cgaatcgata aagactaatt caggcctatt gaggatacca tgagacgatt tctgacgacg
    11341 ctgatgatac tcctggtcgt gctggtggcc gggttatctg cgttagtatt gctggtgaat
    11401 ccgaatgatt tccgcgacta tatggtcaag caagttgctg cacgtagcgg ttatcaattg
    11461 cagctcgacg ggccactgcg ttggcacgtc tggccgcagc ttagtatcct ctccgggcga
    11521 atgtctctca ccgcccaggg cgcaagccag ccactggttc gcgcctacaa catgcgtctg
    11581 gacgtggcgc ttttaccact actgagtcat caactgagcg ttaagcaggt gatgctaaag
    11641 ggggcagtga tccaactgac gccgcagacg gaagctgtgc gcagtgaaga cgctccggtt
    11701 gcaccgcgcg gcaatacctt gccggatctg tcagacgatc gcggatggcc gtttgatata
    11761 tccagtctta aggtggcgga cagcgttctg gtgttccagc atgaagatga cgagcaggtg
    11821 acaatccgca atatccgcct gcaaatggaa caagatcccc aacatcgtgg ctcatttgag
    11881 ttctccgggc gggttaatcg cgatcagcgc gatctcacga tatcccttaa cggtacggtg
    11941 gatgcttctg attatccgca tgatttaatg gcggctattg aacaaattaa ctggcagttg
    12001 cagggtgccg atttaccaaa acaaggtatt caggggcagg ggagtttcca ggtccagtgg
    12061 caggagtcac ataaacgcct ttc
//
LOCUS       DACAOP010000119        11962 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.119, whole genome shotgun sequence.
ACCESSION   DACAOP010000119 DACAOP010000000
VERSION     DACAOP010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11962
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.119"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(296..370)
                     /locus_tag="IT892_003858"
     CDS             complement(296..370)
                     /locus_tag="IT892_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137012.1"
                     /translation="MCDILLNVLNIVFIGIAIILVIIC"
     gene            complement(676..2709)
                     /gene="betT"
                     /locus_tag="IT892_003859"
     CDS             complement(676..2709)
                     /gene="betT"
                     /locus_tag="IT892_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HAP3137013.1"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
                     YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
                     FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
                     GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSTLYEIIHGGAAFAEEAMVHP
                     ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
                     RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
                     SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
                     AYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
                     LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA"
     gene            2838..3425
                     /gene="betI"
                     /locus_tag="IT892_003860"
     CDS             2838..3425
                     /gene="betI"
                     /locus_tag="IT892_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414847.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BetI"
                     /protein_id="HAP3137014.1"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAEQRLQAIVGGNFDETQVS
                     SAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPREQAQEAGYGLAAL
                     IDGLWLRAALSGKPLDKTRANSLTRHFITQHLPTD"
     gene            3439..4911
                     /gene="betB"
                     /locus_tag="IT892_003861"
     CDS             3439..4911
                     /gene="betB"
                     /locus_tag="IT892_003861"
                     /EC_number="1.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine-aldehyde dehydrogenase"
                     /protein_id="HAP3137015.1"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWASMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTE
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMM
                     ANFFSSGQVCTNGTRVFVPAKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGKEEGARVLCGGDVLKGDGFDNGAWVAPTVFTDCSDDMTIVREEIFGPV
                     MSILTYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     gene            4925..6595
                     /gene="betA"
                     /locus_tag="IT892_003862"
     CDS             4925..6595
                     /gene="betA"
                     /locus_tag="IT892_003862"
                     /EC_number="1.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="HAP3137016.1"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
                     DLDNWAQEPGLENWSYLDCLPYYRKAETRDMGENDYHGGDGPVSVTTSKPGVNPLFEA
                     MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIIFDGKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGG
                     TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMSVVDGEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKIADMIRGQEALPRSTAGYFVANGMPVRAKK"
     gene            6808..7476
                     /locus_tag="IT892_003863"
     CDS             6808..7476
                     /locus_tag="IT892_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137017.1"
                     /translation="MREQIKQDIDLIEILFYLKKKIRVILFIMAICMAMVLLFLYINK
                     DNIKVIYSLKINQTTPGILVSCDSNNNFACQTTMTEDVIQRITTFFHTSPDVKNREIR
                     LEWSGDKRALPTAEEEISRVQASIIKWYASEYHNGRQVLDEIQTPSAINSELYTKMIY
                     LTRNWSLYPNGDGCVTISSPEIKNKYPAAICLALGFFLSIVISVMFCLVKKMVDEYQQ
                     NSGQ"
     gene            complement(7719..8414)
                     /locus_tag="IT892_003864"
     CDS             complement(7719..8414)
                     /locus_tag="IT892_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein C"
                     /protein_id="HAP3137018.1"
                     /translation="MDNRGEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLNQQ
                     QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
                     LQQECNAVVWDPAKGAENISQAEQAKVGVVYAEYGLTESGGVVLFSAAERGRSLSLLP
                     EYSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
     gene            complement(8407..9834)
                     /locus_tag="IT892_003865"
     CDS             complement(8407..9834)
                     /locus_tag="IT892_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster-binding protein"
                     /protein_id="HAP3137019.1"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFARTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHERLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDNVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEADGESFRSWFKKHQAQEKKNG"
     gene            complement(9845..10564)
                     /locus_tag="IT892_003866"
     CDS             complement(9845..10564)
                     /locus_tag="IT892_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HAP3137020.1"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPTYLADEPEWASRAA
                     KVAARMQDLTSFIVNKLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVAHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     gene            complement(11091..11945)
                     /locus_tag="IT892_003867"
     CDS             complement(11091..11945)
                     /locus_tag="IT892_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP3137021.1"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFLAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMLEMPGHAWTVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSRETLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
BASE COUNT         3108 a         3168 c         2893 g         2793 t
ORIGIN      
        1 actcaggaga taatcacgca agaatgcaat attaaaattc agatactcat ttttggtaat
       61 aaagaagtag ttggactatt tcaatattta taatttccca ctacatactg gcatccattc
      121 atgagcaaag gcgcattata tgaatttaac aatccagatc aactgaaaat acctctccct
      181 cataaacaca tagcgtcaac attcaatgac ataatgagta aagatgttgg ttatgcatac
      241 gtatcattac tctatgcctg tcccttaaaa acccactcat taagactgaa tccattcagc
      301 aaatgataac caatattata gcaatgccaa taaaaacaat atttaaaaca ttcaataaaa
      361 tatcacacac agataattaa accttaaata acaaatggtt gtgttaattt cagttgattt
      421 acgatacaca tttctcatga ataatgcgtc atttcaaatg atcagcaata tttacattaa
      481 ataagactaa acttattgaa cattcgcaac agcccaaatg taggttttgg gctgcaatag
      541 ttcttttctt ttttattatc tgttgtctgg taatcatcaa tagatactaa gggcttaacc
      601 gtatagatat aacgtatcaa gaggtaggag aaacagcgcc atatgcagac atggcgcggt
      661 tttatgcaat aacaatcacg cgtccgggaa catcacgcta tggcccggcg cttcacgatg
      721 gagatgaata aagttaaggt gccgctcgta ctggtcaaga atatcggtga tcacctgctc
      781 tttgctgtag tccatcaggt cgttgccctg gctgccttct aacaggaagg tttccagccg
      841 gtagtaggtc gatttaccgc tgcgtgcgcg gtaggtaaag cccggcaccg aatattgctg
      901 cggccaaatc tgatagacaa agttttgctc ttcgcccata tgcaccaaca aatccagatg
      961 acccaactgc tgtccctctt ccggtggcag gctttttagc tccacgtacg cgccgcgcaa
     1021 ccgcaactcc tgcgccactt cttccattgc cgggtaacag accgtctcca tcatctgttt
     1081 agtgtaacgc gtgcccggat aattcatcag gcgcgagaga cgttttttcc agctcaggcg
     1141 atcctgaagc cccagcggtc gcggtgcggt atcgcggttg gcactttcac ggcggtaatc
     1201 ttctaccttc agagatttat acaaccccgc catcacgaag aagatcacaa agctgaacgg
     1261 cagccccata atcaccgtgg tgttttgcag cgcggatatc ccgttagtca tcagcatgcc
     1321 gagcgtcagc aggccaatcg ccaccgacca gaagacgcgc agccagccgg gggcgtcgct
     1381 gttgatatct ttaagctgcg aggtgaaatt ccccagcacc agcgccccgg agtccgccga
     1441 ggtcacataa aacagcaggc cagtaatggt ggcgacggag gcgctaaagg taaacgccgg
     1501 atactgcgcc agcaggctgt agaagccgcg ctccggatgg accatcgctt cctcggcaaa
     1561 tgccgcgccg ccgtggatga tttcatacag cgtgctattg ccgaacaccg agagccataa
     1621 cagcgtgaag gtaaacggaa taatcaacgt gcccagcacg aactggcgaa tggtacgccc
     1681 acgcgagata cgcgccagga acaagccgac aaacggcgac catgccaccc accatgccca
     1741 gaagaagagc gtccagttat tcatccactc aaccggacgg tcgaaggcaa aactgttgag
     1801 cgtcatgccc ataaagcgat tcacatagtc gccaacattc agcaccagtg cattaagcag
     1861 gaacgaagtg tcgcccataa acaatacgaa caggatcaat cccagcgcca gcgcgacatt
     1921 aagctccgat aacacgcgaa tgcccttatc gacaccggag gtgacagaga tcgtggcgat
     1981 tatcaccgac aaggcgatca gtgccgcttt cgccgccatc gaatcgggaa tatcaaacag
     2041 tacgctcaag ccatagttaa gctgcaccac accgataccg agcgtagtgg caataccgaa
     2101 gatagtgccg atcaccgctg caatatccac tgagtgacct atcggcccgt taatccgttt
     2161 accgaagatc gggtacagcg ccgagcggat ggtgagcggc aaattataac gatagctaaa
     2221 gtatccgagc gccatgccca tcagcgcata catcgaccag ccggttaagc cgtagtgaaa
     2281 cagcgtccag accatcgcct gacgcgcggc ctcaatcgtc tgtcccgcgc cttccggcgg
     2341 ctgcatatac tgcgttaccg gttcggctac ggagaagaac atcaggtcga taccgatccc
     2401 ggcagcaaac agcatcgccg cccaactcag caggctgaat tccggtttgg attgttctgg
     2461 cccgagcttc accgaaccaa aacgcgaaca agcgatacag accacaaaga caatatagag
     2521 cgttgccgcc agcagatagt accaaccgaa ggttttagaa acccagtcca gcgtgcggcc
     2581 aatccacagg gccgagaagt cgcgaaacag gatcgttgtc agggaaaaca acaaaatcag
     2641 tccggcggag gtgtaaaaca ccaccggatt gattttgtcc ttttccctgc tgtgtgaaag
     2701 gtctgtcatc cagtatcccc actgttattg ttactattta aaatcaaatt cgtaacaatt
     2761 aagacacatt ttatattgaa cgtccaatca ataaccgctt taatagataa acaccgctga
     2821 tgaatggagt ggcgaaaatg cccaaattgg ggatgcagtc gatccggcgc agacaactga
     2881 tcgacgccac actggaagca ataaatgaag tgggcatgca cgatgcaacg atcgcgcaga
     2941 tcgcacgccg tgcaggcgtt tctacgggga tcatcagcca ctatttcagg gacaaaaatg
     3001 gtctgctgga agcaaccatg cgcgatatca ccagtcagct gcgtgacgcg gttttgaatc
     3061 gattacatgc acttccgcag ggcagtgcag agcagcgatt acaggcgatt gttggcggaa
     3121 acttcgatga aacgcaggtg agcagtgcgg cgatgaaagc ctggctggcg ttctgggcca
     3181 gcagtatgca tcagccgatg ctctatcgtt tacagcaggt cagcagccgc cgcttgctgt
     3241 cgaatctggt gagcgagttt cgtcgcgaat tgccgcgcga acaggcacag gaagcgggct
     3301 acggcctggc cgcgctgatt gatggattat ggctgcgcgc ggctctgagc ggcaaaccgc
     3361 tggataaaac ccgcgctaat tccctgaccc gccactttat cactcagcat ctacccaccg
     3421 attaaccgag gagacgtgat gtcccgaatg gcagaacagc agctttatat acatggtggt
     3481 tatacctccg ccaccagcgg tcgcaccttc gagaccatta acccggccaa cggtaacgtg
     3541 ctggcgaccg tgcaggccgc cgggcgcgag gatgtcgatc gcgccgtgaa aagcgcccag
     3601 caggggcaaa aaatctgggc gtcgatgacc gccatggagc gctcgcgtat tctgcgtcgg
     3661 gccgttgata ttctgcgtga acgcaatgac gaactcgcaa aactggaaac cctcgacacc
     3721 ggaaaagcat attcggaaac ctcaaccgtc gatatcgtta ccggtgcgga cgtgctggag
     3781 tactacgccg ggctgatccc ggcgctggaa ggcagccaga tcccgttgcg tgaaacgtcc
     3841 tttgtgtata cccgccgcga accgctgggc gtagtggcag ggattggcgc atggaactac
     3901 ccgatccaga ttgccctgtg gaaatccgcc ccggcgctgg cggcaggcaa cgcaatgatt
     3961 ttcaaaccga gcgaagttac cccgcttacc gcgttaaagc tggctgaaat ttacagcgaa
     4021 gcgggcctgc cggacggcgt atttaacgtg ttgccgggcg tgggcgcgga gaccgggcaa
     4081 tatctgaccg agcatccggg cattgccaaa gtgtcattta ccggcggtgt cgccagcggc
     4141 aaaaaagtga tggctaactc ggcggcctct tccctgaaag aagtgaccat ggaactgggc
     4201 ggtaaatcac cgctgatcgt tttcgatgat gcggatctcg atctcgccgc cgatatcgcc
     4261 atgatggcaa acttcttcag ctccggtcag gtgtgtacca atggcacccg cgtcttcgtt
     4321 ccggcgaaat gcaaagccgc atttgagcag aaaattctgg cgcgcgttga gcgcattcgc
     4381 gcgggcgacg ttttcgatcc gcaaactaac ttcggcccgc tggtcagctt cccgcatcgc
     4441 gataacgtgc tgcgctatat cgccaaaggc aaagaggaag gcgcgcgcgt actgtgcggc
     4501 ggcgatgtac tgaaaggcga tggcttcgat aacggcgcat gggttgcacc gacagtgttc
     4561 accgattgca gcgacgatat gaccatcgtg cgtgaagaga tcttcgggcc agtgatgtcc
     4621 attctgacct acgagtcgga agacgaagtc attcgccgcg ctaacgatac cgactacggc
     4681 ctagcggcgg gcatcgtgac agcggacctg aaccgcgcgc atcgcgtcat tcatcagctg
     4741 gaagcgggta tttgctggat caacacctgg ggcgaatccc cggcagagat gcccgttggc
     4801 ggctacaaac actccggcat tggtcgcgag aacggcgtga tgacgctcca gagttacacc
     4861 caggtgaagt ccatccaggt tgagatggct aaattccagt ccatattcta accaggaggt
     4921 ttatttgcaa tttgactaca tcattattgg tgccggctca gccggcaacg ttctcgctac
     4981 ccgtctgact gaagatccga atacctccgt gctgctgctt gaagcgggcg gcccggacta
     5041 tcgctttgac ttccgcaccc agatgcccgc tgccctggca ttcccgctac agggtaaacg
     5101 ctacaactgg gcctatgaaa cggaacctga accgtttatg aataaccgcc gcatggagtg
     5161 cggacgcggt aaaggtctgg gtggatcgtc gctgatcaac ggcatgtgct acatccgtgg
     5221 caatgcgctg gatctcgata actgggcgca agaacccggt ctggagaact ggagctacct
     5281 cgactgcctg ccctactacc gcaaggccga gactcgcgat atgggtgaaa acgactatca
     5341 cggcggtgat ggcccggtga gcgtcactac ctccaaaccc ggcgtcaatc cgctgtttga
     5401 agcgatgatt gaagcgggcg tgcaggcggg ctacccgcgc acggacgatc tcaacggtta
     5461 tcagcaggaa ggttttggtc cgatggatcg caccgtcacg ccgcagggcc gtcgcgccag
     5521 caccgcgcgt ggctatctcg atcaggccaa atcgcgtcct aacctgacca ttcgtactca
     5581 cgctatgacc gatcacatca tttttgacgg caaacgcgcg gtgggcgtcg aatggctgga
     5641 aggcgacagc accatcccaa cccgcgcaac ggccaacaaa gaagtgctgt tatgtgcagg
     5701 cgcgattgcc tcaccgcaga tcctgcaacg ctccggcgtc ggcaacgctg aactgctggc
     5761 ggagtttgat attccgctgg tgcatgaatt acccggcgtc ggcgaaaatc ttcaggatca
     5821 tctggagatg tatctgcaat atgagtgcaa agaaccggtt tccctctacc ctgccctgca
     5881 gtggtggaac cagccgaaaa tcggtgcgga gtggctgttt ggcggcactg gcgttggtgc
     5941 cagcaaccac tttgaagcag gtggatttat tcgcagccgt gaggaatttg cgtggccgaa
     6001 tattcagtac catttcctgc cagtagcgat taactataac ggctcgaatg cagtgaaaga
     6061 gcacggtttc cagtgccacg tcggctcaat gcgctcgcca agccgtgggc atgtgcggat
     6121 taaatcccgc gacccgcacc agcatccggc gattctgttt aactacatgt cgcacgagca
     6181 ggactggcag gagttccgcg acgcaattcg catcacccgc gagatcatgc atcaacccgc
     6241 gctggatcag tatcgtggcc gcgaaatcag ccccggtgtc gaatgccaga cggatgaaca
     6301 gctcgatgag ttcgtgcgta accacgccga aaccgccttc catccgtgcg gtacctgcaa
     6361 aatgggttac gacgagatgt ccgtggttga cggcgaaggc cgcgtacacg ggttagaagg
     6421 cctgcgtgtg gtggatgcgt cgattatgcc gcagattatc accgggaatt tgaacgccac
     6481 gacaattatg attggcgaga aaatagcgga tatgattcgt ggacaggaag cgctgccgag
     6541 gagcacggcg ggatattttg tggcaaatgg gatgccggtg agagcgaaaa aatgagtcgt
     6601 gatgtgaact aacgcaggaa ccgatcagat tgagagttac cgttccagag agggggaccg
     6661 aatccttata taaacactga ggtaactctc atgcttcata tccagtattc atgatgcggg
     6721 ctttttgctg atatttaacc cgaacattcc tgatacagac tattaataca accttatctg
     6781 cgacagattt tattctctgg atatattatg cgtgaacaaa tcaaacagga tatcgatctg
     6841 attgagattt tattttatct gaagaaaaag attcgtgtta tcctttttat tatggctata
     6901 tgtatggcta tggtgctgtt gtttctgtat atcaataaag acaatataaa agtgatttac
     6961 agcctaaaaa taaaccagac aacgccaggt atacttgtta gctgtgatag caataataat
     7021 tttgcctgtc agactacaat gactgaagat gttattcagc gaattactac attttttcac
     7081 accagcccag atgtcaagaa cagagaaata aggctggaat ggtcaggaga taagagagct
     7141 ttaccaactg ctgaagagga aatatctcgc gtgcaggcct ctattatcaa atggtatgcg
     7201 tcagaatatc ataatggcag gcaagttctc gatgagatac aaacgccttc agcaattaac
     7261 agtgagcttt atacaaaaat gatatacctg accaggaact ggtcattgta tccgaacggt
     7321 gatggctgtg taactataag ctcaccagaa ataaaaaata aataccctgc tgccatttgc
     7381 ctggctctgg gattttttct aagcattgta atttctgtaa tgttttgcct tgtcaaaaaa
     7441 atggtagatg aataccaaca aaactctggg cagtaataaa caacattctg atagagagtg
     7501 cctgtataaa gctgaagtga caatgaccgg gaagggaacc cgttttcagg aatggatgcc
     7561 tgtctttttc actgtaaata tcctggcatt ggtaatacca ggatatttac agaagagcag
     7621 cataaccatg acggaacggg gttaagtcag gttgtcctaa acgctatttt caacctcgta
     7681 tgccttcttc aggtttatgt ccagacttca tatctctctc aacaatcctc aataatcaga
     7741 tacaccgctt tcaccgggcc atgaactccg acgactttga taagctcaat atccgccgtt
     7801 gaactggggc cgctaatgat gttaatgcag gaaggcattc gttcaccggc ctgcgctttc
     7861 tgatgcaatt tttctgcgag ttgcgctaca cgcggcagga tagtgctttt acgcaggata
     7921 aaaagagaat attccgggag caggctcaat gaacgcccgc gctcggcggc ggaaaaaaga
     7981 accacgcctc ccgattcggt taaaccatat tcagcataca caacacccac tttagcctgc
     8041 tctgcctgcg agatattctc ggcacctttc gccggatccc aaacaacggc attgcattcc
     8101 tgctgcaaac gttcgctaat ccccaattcc tccagcctcg tgtcaccgct aatcacgacc
     8161 gactgatctc ccagctcttt acacagacgt attgcagctt ctgccgcctt cgcctcgctg
     8221 gtcagctcac agcgcgtcaa cataacatcg ctggcaaact gaataaacgc gtcacagcgc
     8281 tgctgttggt taagttgggt aagccgctcg ttagcatagt tgttaagcgg cgcatcttct
     8341 gcttgcggtt caagtcgcag cgggcgaccc agtgcctgag caacgttatt caaaaattcg
     8401 cctcgattat ccattctttt tctcctgcgc ctgatgtttc ttaaaccaac tacggaaact
     8461 ctctccgtca gcttcaggaa gatcgcgtgc ttccatccag tcgctaatcg cgccaaattt
     8521 gagtggtgtt ttgccgccat tgataaacca gcttgccgca tgagcaccgg ccatcatccc
     8581 gactttccac aatcctggat gactattggc ataagcgaac atttttatcg cccgttgctc
     8641 tgcttttgcg gtgatccctt tttcagccat cacccgacga tgacgcaaaa tcagttttga
     8701 cagcggaata cgcaccggac acacgttgtc acaagctgtg cataaagagc aggcgtaggg
     8761 taaatcttta aaatctttat agccgccaag tagcggagaa atcaccgcac caattggccc
     8821 tggataaata gagccatatc catgaccgcc aatatggcga tatgccggac aagtattcat
     8881 acaagccccg cagcgaatac agcgcagcac atcccgaaat tcagaggcca gcacctcaga
     8941 acgcccgtta tcgacaataa ccagatgaaa ctcttcagga ccatcaacgt gcccagcttc
     9001 gcgcggtcct gtcagccagg tgttgtatcc cgtcaaacgt gcaccaacgg cactgcgcgc
     9061 cagcatggtg atcaatacat ctacctcggc aaacgtgggg gcaatacgct ccattcccat
     9121 cactgcaata tgcgttttag gcagcgtggt acacattcgc gcattacctt cattggtcac
     9181 caggcatacc gaaccggtct ctgccaccgc gaaattacag ccggtaatac ctatttcagc
     9241 actgaggaaa tcttcgcgga ttttttgccg gatgaataag gtcatcgctt caggcgtttc
     9301 cggcccctca tagcccagac gttcgtgtag cactcgacgg atctgatggc gatctttatg
     9361 aattgccggg accacaacat gagatggcgg atcttgatcc agctggagaa tatattcacc
     9421 cagatcggtt tcaatcacct gaatgccagc atcctgcaac acatgattga caccaatctc
     9481 ttcggtcacc atcgatttag atttcaccac cttccgggca tttttgcgtt gggcaacctg
     9541 taaaatgtag cgggtagcgt cttctttggt tcttgcaaaa tagacgtgac cgccgttttg
     9601 cgtcactttt tctgagagct ggtacagata agcgtcgaga ttactcagaa catgatcacg
     9661 tatctgggcg gcccgatcgc gccactcctc ccagtgcccc aattcatcga ccattttttg
     9721 ccgatttgcc ccaatacgct gctgcgcgtt tgccaccgct ttgcgcatga tcggatcttc
     9781 aatttgctga cggatgcgtg tcttaaaatc tgtattactg gttttgatcg acatctttat
     9841 atcctcagcg gctcatcaac acttcagcaa tatgcatcac tttgactttc tgcccttccc
     9901 gttgtaatcg cccactgatg tttagcaggc aactcacgtc agcaccaatt aaatactcag
     9961 ggcggacttc catcaggtgc gcaacctttt ctttcaccat ctcgccggat atttcggcca
    10021 ttttgaccga gaacgtgccg ccaaatccgc agcaggtatc ctgttcagca aaggtcaaca
    10081 gctccagtcc acgcacattt ttcagcagcg taagtggctc gtccttcact cccagcttac
    10141 gggccaggct acaagatggg tgatacaccg ctctcccttg caaactggca cctacatcga
    10201 ctacccctaa tttattaaca ataaaagagg tgagatcctg catacgcgcg gcaacctttg
    10261 cggcacgtga tgcccattca ggttcatccg ccagatacgt cgggtaactt tttacggcat
    10321 aggtgcaaga gccagccggt gaaataatgg gatcgtcgtt atcctccagt gcggcgatca
    10381 gatttttcat ccctggaatc gcttctttga tataaccgct attgatcgca ggctgaccgc
    10441 agcatccctg tttctccggg aaatttacgc gacagccgag tttttccagt agcagcacgg
    10501 agtctcgtgc cattcttgat ttcagggcgt caccaataca ggtgacaaag aaattgacat
    10561 tcacaactaa tactccatta cttcatgccc atttatgccc gatgtttccc ccccaccggg
    10621 ggatcaatca tcaataaata tggcgttctt ttttaattgg ctagcaacat accacccctc
    10681 atttgtatga caaatgataa tctttcatcc aaacgtcaaa tgcaataact aattttattt
    10741 ctttcggcat cgctcacatt ttatggggaa atcgacgatc atttttggca taagaaatcc
    10801 atttaaaaat ggctacatcc cttataccta ttcagagcta cttattcagg ggttattgag
    10861 atatacactg atggtgtaca aaaaaatcac cgacaataat cacgtatcaa gtaatagtcg
    10921 ggattttatt taattgaagc aatttagttt gcatttttat ttaaaaactg agctagagtc
    10981 catcagaaaa aatatataaa gcccaaacca ccgttggaaa tagaaatagt tgaaaggctc
    11041 acaactcccg gaatgcggat tatctttgcc ctgatttctg gcggttttat tcagggtgca
    11101 agctgtctga ccctttccct atattctccc ggggtacaac caaactcgcg gacaaacgcc
    11161 ttgtgaaaag atgattcact ggcatagcct actgactcag cgatcaccac aacagggagc
    11221 gtttcccggg aaaacatctg ggccgctatt tgtagacgca actttgttaa tacagccagc
    11281 ggcgtggttc cggaaacatc acggaaaagc tgggcaaaac ttgcccggga catgtgagcg
    11341 atgctggcca gcgattcgac ggtccaggcg tgtcctggca tttccagcat ttgctgtatt
    11401 accgcaccaa gacgtggatg cagaagcaaa ctgagaatgt ttttctcagt attaacctgt
    11461 gcaatccact cacgcaccgc gagggtaaag aatgtagcgc agatctggct acacagtgca
    11521 tccactcccg gcattgccga tctggattcc tgttgtaaaa acgggatcgc ctccctcagc
    11581 cagttatatt ccacgctgtg gttaaccggt gctaaaaaca gcgtttccgg caaagacgtt
    11641 aaaaaataac gcgccgaatg ttgcaaccga agagtgccgc agacaataca ggtcgattca
    11701 ttatcgacat gactcaggcg atgagctgaa ttttgtggta gcaggaccac atttcccggg
    11761 cgtaatgtaa aaatctcccc cgtcggcatt tccagcttcg ccgctccttg cgttaacgca
    11821 tgccaacgaa taaccgataa ttccccggca ccatgtggaa gctgccagtc acttcctaac
    11881 acgcaattct tatcgatcgt tccttgtgga gcgttaagca tcaacaaacg gctaagggca
    11941 tccatatcag actcctgagt gg
//
LOCUS       DACAOP010000120        11926 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.120, whole genome shotgun sequence.
ACCESSION   DACAOP010000120 DACAOP010000000
VERSION     DACAOP010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11926
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.120"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(223..1413)
                     /locus_tag="IT892_003868"
     CDS             complement(223..1413)
                     /locus_tag="IT892_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP3137022.1"
                     /translation="MPLTARQVETAKPKDKIYKIADGGGLYLQVNPNGSKYWRMKYHY
                     AGKEKKLSFGTYPTITLAEARKRRDEAKKIHADGKDPGEVKKAENLEKNLSEGRTFAA
                     IATEWYNAKVSGWSASYADYVDRAFKNNVFPYIGNRPISEIEPLELLAVLQRIESRGA
                     CELANKVRQRCGEVFRYAIVTGRARYNPASDLVIAMKSYKRTHYPFLLPPELPEFLYK
                     LENYTGSIVTREATKLLMLTGLRTVELRMGEWCEIDFTQKIWEVPPTRMKMRKEHIVP
                     LSDQAIQSLQILKELTGRYRYIFAGRNDVNRPISDASVNMVLKKIGYDKKATGHGFRH
                     TMSTVLHEQGFNSAWIEMQLAHTDKNSIRGTYNHARYLEGRREMMQWYADYLDALRKE
                     SPAI"
     gene            complement(1589..1663)
                     /locus_tag="IT892_003869"
     tRNA            complement(1589..1663)
                     /locus_tag="IT892_003869"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1628..1630),aa:Arg,seq:cct)
     gene            complement(1739..2671)
                     /locus_tag="IT892_003870"
     CDS             complement(1739..2671)
                     /locus_tag="IT892_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HAP3137023.1"
                     /translation="MDNDKIDQHSDEIEVESEEKERGKKIEIDEDRLPSRAMAIHEHI
                     RQDGEKELERDAMALLWSAIAAGLSMGASLLAKGIFHVELEGVPGSFLLENLGYTFGF
                     IIVIMARQQLFTENTVTAVLPVMQKPTMSNVGLLMRLWGVVLLGNILGTGIAAWAFEY
                     MPIFNEETRDAFVKIGMDVMKNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIIL
                     MTWLIALGDTTHIVVGSVEILYLVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMS
                     HAQIRNDMSNKRKAEARQKAERAENIKKNDKNPA"
     gene            2965..3720
                     /gene="mlaA"
                     /locus_tag="IT892_003871"
     CDS             2965..3720
                     /gene="mlaA"
                     /locus_tag="IT892_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding lipoprotein MlaA"
                     /protein_id="HAP3137024.1"
                     /translation="MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNF
                     NVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTR
                     FFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRD
                     DGGDMADGLYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYF
                     QRHDFIANGGELKPQENPNAQAIQDDLKDIDSE"
     gene            complement(3899..5146)
                     /locus_tag="IT892_003872"
     CDS             complement(3899..5146)
                     /locus_tag="IT892_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000937803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137025.1"
                     /translation="MLPSISINNTSAAYPESINENNNDEVNGLVQEFKNLFNGKEGIS
                     TCIKHLLELIKNAMRVNDNPDRFNINNSSVTYINIDSNDTDYITIGIDNQEPIKLLAS
                     YKDKELARTIINDNIVEKTHDDINNAEFTDGSIVVSGNEGAIDSNDTADITSGIYNQE
                     PIKSPTNDENKKVGQTIIHENVVENTHDINNKEMIFSALKEIYDGDPGFIFDKISQKL
                     RHTITEFDENGKSEPTDLFTWYGKDKKGDSLAIVIKNKNGNDYLSLGYYDQDDYHIQR
                     GIRINGDSLTQYCSEKARNASAWFESSKAIMAESFATGSDHQVVNELNGERLREPNEV
                     FKRLGRAIRYNFQVDDAKFRRDNVKEIISTLVDNEVDRSQNKYDHFKEIEDKVEKRLQ
                     NRQAKYQNEINQLSALGVNFDDN"
     gene            complement(5512..6852)
                     /gene="fadL"
                     /locus_tag="IT892_003873"
     CDS             complement(5512..6852)
                     /gene="fadL"
                     /locus_tag="IT892_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311254.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid transporter FadL"
                     /protein_id="HAP3137026.1"
                     /translation="MSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSG
                     EGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVNISGTSPSDRSLKADNIAPTA
                     WVPNMHFVAPINDQFGWGASITSNYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYR
                     LNNAWSFGLGFNAVYARAKIERFAGDLGQLVAGQIMQSPAGKTPQGQALAATANGIDS
                     NTKIAHLNGNQWGFGWNAGILYELDKNNRYALTYRSEVKIDFKGNYSSDLNRAFNNYG
                     LPIPTATGGATQSGYLTLNLPEMWEVSGYNRVDPQWAIHYSLAYTSWSQFQQLKATST
                     SGDTLFQKHEGFKDAYRIALGTTYYYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRF
                     WLSAGTTYAFNKDASVDVGVSYMHGQSVKINEGPYQFESEGKAWLFGTNFNYAF"
     gene            7224..7508
                     /locus_tag="IT892_003874"
     CDS             7224..7508
                     /locus_tag="IT892_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF406 family protein"
                     /protein_id="HAP3137027.1"
                     /translation="MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTL
                     AALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR"
     gene            7689..8999
                     /gene="fadI"
                     /locus_tag="IT892_003875"
     CDS             7689..8999
                     /gene="fadI"
                     /locus_tag="IT892_003875"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadI"
                     /protein_id="HAP3137028.1"
                     /translation="MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMV
                     VGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATS
                     FQAIANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLF
                     SRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWS
                     DGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLT
                     DGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTM
                     SDLTLIDMHEAFAAQTLANIQLLGSERFARDVLGRAHATGEVDDSKFNVLGGSIAYGH
                     PFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVVEAE"
     gene            8999..11143
                     /gene="fadJ"
                     /locus_tag="IT892_003876"
     CDS             8999..11143
                     /gene="fadJ"
                     /locus_tag="IT892_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadJ"
                     /protein_id="HAP3137029.1"
                     /translation="MEMASAFTLNVRLDNIAVITIDVPGEKMNTLKAEFASQVRAIIK
                     QLRENKELRGVVFISAKPDNFIAGADINMIANCKTAQEAEALARQGQQLMAEIHALPV
                     PVIAAIHGACLGGGLELALACHGRMCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIG
                     VSTALEMILTGKQLRAKQALKLGLVDDVVPQSILLEAAVELAKQDRPSSRPLPVRERI
                     LAGPLGRALLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGEL
                     AMTPQSQALRSIFFASTEVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGLP
                     VRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERDRQLALISGTTDYRGFAHRDLI
                     IEAVFENLELKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSP
                     VEKMPLVEIIPHAGTSAQTIATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIR
                     MLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVV
                     SSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGTQGQGRLSAPQVAERCVM
                     LMLNEAVRCLDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLA
                     TQYGSRFTPCERLVEMSKRGESFWKTTATDLQ"
     gene            11346..11831
                     /gene="sixA"
                     /locus_tag="IT892_003877"
     CDS             11346..11831
                     /gene="sixA"
                     /locus_tag="IT892_003877"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohistidine phosphatase SixA"
                     /protein_id="HAP3137030.1"
                     /translation="MQVFIMRHGDAALDAASDSVRPLTTNGCDESRLMANWLKGQKVE
                     IERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELTPCGDVGLVSAYLQALTNEGVAS
                     VLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGNGTFNWQMSPCNLKMAKA
                     I"
BASE COUNT         2962 a         2722 c         2936 g         3306 t
ORIGIN      
        1 tattgtctat tacagctcca gttaatagag cctgaagtaa tttcttagta tttcatcata
       61 agcgtttatc tatcgtctct ttctaaatta accggtcgta ttacaaggtg ctgaatctga
      121 ttaaggaatg atacttaggg gattatggct gacttaataa ttagataact gataaatgac
      181 tatcaggggg atattgttaa gtcagccttt aaaatcaagc gattatatag ctggtgactc
      241 ttttcgaaga gcatcaaggt agtcagcgta ccattgcatc atttctcgtc ttccttcaag
      301 gtaacgagca tggttgtatg taccacgaat gctgtttttg tccgtatgtg caagttgcat
      361 ttcaatccat gcactattga atccttgctc gtgtagaaca gtactcattg tatgacgaaa
      421 tccatgcccg gtagcttttt tgtcatagcc aatcttcttc aaaaccatat tgacgcttgc
      481 atcgctgata ggcctgttaa catcatttct tccggcaaag atgtatctgt atcttccagt
      541 cagttctttg aggatttgca gagactggat tgcctgatct gacagaggga cgatatgctc
      601 cttcctcatt ttcatccggg tcggaggaac ttcccatatc ttttgggtaa aatcgatctc
      661 acaccattcc cccatacgta attctactgt tctcagccct gtgagcatca acaattttgt
      721 agcttcacgg gttacaatac tgccggtgta gttttcgagt ttgtataaaa actctggtag
      781 ttcaggagga agcaggaaag ggtaatgtgt tcgcttatag cttttcattg ctataaccag
      841 atcagaagct ggattgtatc gtgcccgacc tgtaacaatg gcataccgaa acacttcacc
      901 acatcgttgg cgaactttat tagctagctc gcaggctcct cggctttcga tacgctgaag
      961 aactgcgaga agttcaagag gttcgatttc actaatgggt ctgtttccaa tgtagggaaa
     1021 cacattattt ttgaatgctc tgtcgacata atcagcgtag ctggcagacc agcctgaaac
     1081 ttttgcgttg taccactcgg tggcgattgc ggcaaaagtt cttccttcgg aaaggttttt
     1141 ctcaagattt tcagctttct tgacttcacc gggatcttta ccatcggcat gtattttctt
     1201 ggcttcatcc cgacgtttgc gagcttcagc caatgtaata gttggatagg tgccaaatga
     1261 tagtttcttt tccttccccg catagtggta cttcattcgc cagtactttg agccgttagg
     1321 attgacctga aggtagagcc caccaccatc ggcaatctta taaattttat ctttgggttt
     1381 ggctgtttca acttgtcgag ctgtcagtgg catctggggg cctcgcaata gattgaccaa
     1441 gatgtgcccc taaataggcc cccaaatgtg acttgattta cgttcccctg aggagaatta
     1501 aggcgactat ttgagtaaca taagtaaggg tatgtgctga ttataaaggc tttttgtggg
     1561 gtatggtaga tttcaggaga ggtgtgcatg gtgtcccctg caggaatcga acctgcaatt
     1621 agcccttagg aggggctcgt tatatccatt taactaagag gacaatgcgg catgagtata
     1681 cccgctaatg gactgcgggg taagtacgct gccgctcgat tgcttaaacc ctcgccattt
     1741 atgccgggtt tttatcattt ttcttaatgt tttccgcacg ttctgctttt tggcgtgctt
     1801 ctgctttgcg cttgttgctc atgtcgttgc ggatctgtgc atgactcatt aacgcgaaga
     1861 taaaggtgcc gccgcagatg ttccccgcta aagtaggtag tgcgaagggc cagatgaaat
     1921 cgctccagtg cagcgtaccg ttaaacacca gatagaggat ttcaacagaa ccgacaacga
     1981 tgtgagtggt gtcacccagg gcaataagcc aggtcatcaa tataatcacc acaatctttg
     2041 ccgcacccgc tgcaggaaac atccatacca tagtggcgat cagccagccg gaaatgatcg
     2101 cgttggcaaa catctcgctg ggggtgttct tcatcacatc catgccgatt ttgacaaatg
     2161 catcgcgagt ttcttcattg aagattggca tatattcaaa tgcccacgcc gcaatacctg
     2221 tcccgagaat attacccagc agcacgacgc cccataaccg cataagtaag ccaacgttgc
     2281 tcattgtcgg tttttgcatg acgggtagta ccgcagtcac ggtgttttcg gtaaataatt
     2341 gctggcgggc cataatgacg ataataaaac caaaggtata accgagattc tccagcaaga
     2401 agctgcccgg cacgccttcc agttcgacat gaaatatccc ttttgccagt agcgaagcgc
     2461 ccatcgacag acccgccgca atggctgacc acagtagtgc cattgcgtcg cgttccagct
     2521 ctttttcacc atcctggcgg atatgctcat gaattgccat cgcccgggag gggagtcggt
     2581 cttcatctat ttctattttt ttgccgcgct ctttttcttc gctctcaact tcaatttcgt
     2641 cgctgtgttg atcaattttg tcgttgtcca tggtctcttc tcttgaatta gcacgtatag
     2701 ctaaagcgta gcggcttttt tgctcgcaac tggcgggagt tactctgaaa atgtagaaaa
     2761 ggccgcgttt gcctttttct gtttctatag aatcaagtag cctacagggc ggcgattacc
     2821 aggctatgat caaatcagca aatcagggcg tctggacatc agttgacgtg ctgttacaat
     2881 cgcccacacc taaacaggcg gatacggtat cgttccgtca tggatggcaa actgcataag
     2941 ccataaaaaa acagggagac atttatgaag cttcgcctgt cggcgcttgc tctgggaact
     3001 acgcttctgg tggggtgtgc gagttccggt acagatcagc aagggcgttc tgacccgtta
     3061 gaagggttca accgcaccat gtacaacttc aacttcaatg tattagaccc gtatattgtt
     3121 cgaccggtcg ctgtcgcctg gcgtgattat gttccgcaac cggcgcgtaa cggtttgagc
     3181 aactttactg gcaaccttga agaacctgcg gtgatggtta actacttctt gcagggcgac
     3241 ccttatcagg ggatggtcca ctttacccgc tttttcctga acaccatttt ggggatgggc
     3301 ggctttattg atgttgcagg gatggcgaac ccgaaactgc aacggactga acctcaccgc
     3361 ttcggtagta cgcttggtca ttatggtgtg ggttatgggc catacgttca gttaccgttc
     3421 tacggtagct tcacgctgcg tgatgacggt ggtgatatgg cggatggtct ttacccggtt
     3481 ctttcctggc tgacctggcc gatgtctgtg ggtaaatgga cgcttgaagg gatagaaact
     3541 cgtgcgcagt tgttggattc cgatggtctg ctgcgtcagt cgtccgatcc ttatattatg
     3601 gtgcgcgaag cgtacttcca gcgtcatgat ttcatcgcta atggcggcga actcaaaccg
     3661 caggaaaatc cgaacgcgca agcgattcag gatgatttaa aagatatcga ttctgaataa
     3721 gaaacaaata aaaaaggtga gtcacaaaac tcaccttttt tgttgttatc cctcaattac
     3781 cccaagtaaa agaagataaa ccgacaatga cctggacata attatgtaaa aatactgatg
     3841 ttcgtcattg tctgtttccg atattcagac gttgaaaaat caaaaaaact ggacaatttt
     3901 aattatcatc aaaattaaca cccaatgcag atagttgatt aatttcattt tgatatttag
     3961 cctggcgatt ttgaagcctt ttttcaactt tatcttcgat ttccttaaag tggtcatatt
     4021 tattttgaga acggtcaact tcgttatcga ctaaagtaga aattatttct tttacattat
     4081 cgcgtctaaa ttttgcatcg tccacttgaa aattatatct tattgctcga cctaaacgtt
     4141 taaaaacttc gtttggctct ctcagtcttt ccccgttgag ctcgtttaca acctgatgat
     4201 cggaacctgt tgcaaatgat tctgccatga tagctttact gctttcaaac cacgctgaag
     4261 cattcctggc tttttcacta caatattggg tgagactatc accattaata cgaattcctc
     4321 tttgaatgtg gtagtcgtcc tgatcatagt aaccgagaga taagtaatca tttccgtttt
     4381 tatttttaat tacaatagcg agagaatcgc cttttttatc tttaccgtac caggtaaata
     4441 agtccgttgg ttcgcttttc ccattctcat caaattccgt tatcgtatgt ctgagttttt
     4501 gtgatatctt atcgaagata aaaccaggat ctccatcata tatttctttt aatgcgctga
     4561 agatcatttc cttgttattg atatcatgag tattctctac tacattttca tggatgatgg
     4621 tttggccgac ttttttgttt tcatcgttcg taggtgattt tattggttct tgattataga
     4681 taccactagt aatatcggct gtatcattgg agtcaatagc accctcatta ccactaacaa
     4741 cgatactacc atcagtaaat tcagcattat ttatatcatc atgagtcttc tcaactatgt
     4801 tgtcattaat gatagtacgg gcgagttctt tgtctttata gctcgcaagt aattttattg
     4861 gttcttggtt atcgatacca atagtaatat agtctgtatc attggaatca atattaatat
     4921 aagtaactga ggaattatta atattaaatc tatcaggatt gtcgtttact cgcatggcgt
     4981 tttttataag ctcaagcaaa tgtttaatac aggtgcttat tccttcctta ccattaaaaa
     5041 ggtttttgaa ctcttgtact aatccattaa cttcatcatt gttattttca ttgatggatt
     5101 ctgggtaagc tgcgctggta ttgttgattg aaatagatgg tagcatgatt ttattccatg
     5161 ttgattgatt tgttacaaat atatattacc taataaaata gactatcaaa aaacgctcat
     5221 ttatttagag cctatcttta atttgagtgt atgagcgcac aatagccagg gaggttgagt
     5281 atcctggaaa tgcagaaaag taaactcttt gagaaggacg agcagaacgc ctgaaaatat
     5341 gcgtttccct tcaggtttgt ctgtggatac cacttactga tttgaaaggg caagctgcca
     5401 tcaggctgtt tgcaaaactc aggaggcaag caatgaggaa actactttcg gtgaagtggg
     5461 ggagttaaag tcacctgcat agctggtgac tttatccagg cgaacgcgtt atcagaacgc
     5521 gtagttaaag ttagtaccga acagccaggc tttaccttca gactcgaact ggtatgggcc
     5581 ttcgttaatt ttcacgctct gaccgtgcat ataagaaaca ccaacatcga ctgaagcatc
     5641 tttattaaat gcgtaagtcg tacctgcact cagccagaaa cggtcctggt ccggaatgga
     5701 gatagaacga ttctgtgccg gaactgggct gtcatcaaag gcgataccgg tacggaaggt
     5761 ccagttatca tcgtagtaat aagtggttcc caacgcgatg cggtaagcat ctttaaagcc
     5821 ttcatgtttc tggaacagcg tgtcgccact cgttgaggtc gctttcagct gctggaactg
     5881 actccagctg gtgtaagcca ggctatagtg aatcgcccac tgcggatcaa cacggttata
     5941 acccgacact tcccacattt caggcaggtt cagcgtcaga taacccgatt gcgttgcgcc
     6001 acctgtcgcg gtaggtattg gtaaaccgta gttattaaac gcacgattaa gatcgctgct
     6061 gtagttacct ttgaagtcaa ttttcacttc agaacggtag gtcagtgcat agcggttatt
     6121 tttatccagt tcatacagga taccggcgtt ccagccaaag ccccactggt taccgttcag
     6181 atgagcgatt ttggtattac tgtcgatacc gttggcggta gctgccaatg cttgcccttg
     6241 aggagtcttc ccggcaggag attgcatgat ctgaccggca accagctgcc ccagatcgcc
     6301 tgcgaaacgt tcaatcttcg cgcgagcgta gacggcgttg aaaccaagac caaagctcca
     6361 tgcattattt aagcgatacg caccgcttaa gttcaggttc atggtttcaa ggtcggttgt
     6421 acccccgaca gagccgcctg cataagtatc gttaaactct gttgccaggc catagttaga
     6481 ggtaatagaa gcgccccaac caaattggtc gttaatcggt gcaacaaagt gcatgttcgg
     6541 aacccatgcc gtaggcgcga tgttatcggc tttcaggcta cgatcagatg gagacgttcc
     6601 gctgatattt acatccggat caatataaac cgcacccgca gaaaatgtcg ggcggtcaaa
     6661 catggtaatc aatgcggggt tacggctaac gttacctgca tcatcggcaa ttgcaccttc
     6721 ccctgaataa gcccggccca ggccagagga agaaaattcg tttaactgaa agcctgccga
     6781 ccaggcctgg gtggagataa gtgccactgc gactgcgaga gcagactttg taaacagggt
     6841 tttctggctc atgaccataa cctcaatgat ttatttttat acaaactatg ttacgtgctg
     6901 taacaggagc gcgaagtgta gggtctgagg tacatcttag aaatcagacc agtggcgaga
     6961 gtataggtcg gaccagctgg aatgttgcaa gtatgtttct atcttttttc aaatatgatc
     7021 taagaaacgc gatccagctg gcaaaatttg gaggtggcgc actcatggat tcgggtgaat
     7081 tttgttttag atcattttta agtgtgattt cggtcactta tccgattttg cagaattaac
     7141 aactggagca gcactttccg gaagcgtaaa atatccacaa cgtttatctg gcaccttggg
     7201 tgcacataca gaggaaatca acgatgagta aatgtagtgc tgatgaaacc ccggtttgct
     7261 gctgtatgga tgttggcacc attatggaca actccgactg caccgcgtct tacagccgcg
     7321 tgtttgcaaa ccgcgcagaa gcagaacaaa cgctggcggc gctgactgaa aaagcccgta
     7381 gcgtggaatc cgaaccgtgc aaaatcaccc cgactttcac tgaagagtct gacggtgtgc
     7441 gcctggatat cgatttcact tttgcctgcg aagctgaaat gctgatcttc cagctgggtc
     7501 tgcgttaatt cctctcgggt acgtacgccc ctgtcagttg ttggcagggg cgttttattt
     7561 tctcttctac ttttctctct gtgtcatagc tcccactttc ccttttctcc acttggctaa
     7621 atgtaaaaaa atagttaaga ctatgatcag gtcagaccac tttatttatt attttacagg
     7681 ggagtgttat gggtcaggtt ttaccgctgg ttacccgcca gggcgatcgt atcgccattg
     7741 ttagcggttt acgtacgcct tttgcccgcc aggcgacggc ttttcatggc attcccgcgg
     7801 ttgatttagg gaagatggtg gtaggcgaac tgctggcacg cagcgagatc cccgccgaag
     7861 tgattgaaca actggttttt ggtcaggtcg tacaaatgcc ggaagccccc aacattgcgc
     7921 gtgaaattgt tctcggcacc ggaatgaatg tgcataccga tgcttacagc gtcagccgcg
     7981 cttgcgctac cagtttccag gcgattgcaa acgtcgcaga aagcctgatg gcgggaacta
     8041 ttcgcgcggg gattgccggt ggggccgatt cctcttccgt attgccaatt ggcgtcagta
     8101 aaaaactggc gcgcgtgctg gttgatgtca acaaagctcg aaccatgagc cagcgcctga
     8161 aactcttctc tcgcctgcgt ttgcgcgact taatgccggt gcctccggca gtggcggaat
     8221 actctactgg cttacggatg ggcgacaccg ctgaacaaat ggcgaaaacc tacggtatta
     8281 ctcgcgaaca gcaagatgca ttagcgcacc gttcgcatca gcgagccgct caggcgtggt
     8341 cagacggtaa actcaaagaa gaggtgatga ctgcctttat ccctccttat aaacaaccgc
     8401 ttgtcgaaga caacaatatt cgcggtaatt cctcgcttgc cgattacgca aagctgcgcc
     8461 cggcgtttga tcgcaaacac ggaacggtaa cggcggcaaa cagtacgccg ctgaccgatg
     8521 gcgcggcagc ggtgatcctg atgactgaat cccgggcgaa agaattaggg ctggtaccgc
     8581 tggggtatct gcgcagttac gcatttactg cgatagatgt ctggcaggac atgttgctcg
     8641 gtccggcctg gtcaacgccg ctggcgctgg aacgtgccgg tttgacaatg agcgatctga
     8701 cattgatcga tatgcacgaa gcctttgcag ctcagacact ggcgaatatt cagttgctgg
     8761 gtagcgaacg ttttgctcgt gatgtactgg ggcgtgcaca tgccactggc gaagtggacg
     8821 atagcaaatt taacgtgctt ggcggttcga ttgcttacgg gcatcccttc gcggcgaccg
     8881 gcgcgcggat gattacccag acattgcatg aacttcggcg tcgcggcggt ggatttggat
     8941 tagtgaccgc ctgtgctgcg ggtgggcttg gcgcggcaat ggttgtggag gcggaataat
     9001 ggaaatggca tcagcgttta cccttaatgt ccgtctggac aacattgctg ttatcaccat
     9061 cgacgtaccg ggtgagaaaa tgaataccct gaaggcggag tttgcctcgc aggtgcgcgc
     9121 cattattaag caactccgtg aaaacaaaga gttgcgcggc gtggtgttta tctccgcgaa
     9181 accagacaac ttcattgctg gcgcagacat caacatgatc gccaactgca aaacggcgca
     9241 agaagcggaa gcactggcgc ggcagggtca acagttaatg gcggagattc atgctttgcc
     9301 cgttccggtt atcgcggcta ttcatggcgc ttgcctgggc ggtgggctgg agttggcgct
     9361 ggcgtgccac ggtcgcatgt gtactgacga tcctaaaacg gtgctcggtt tgcctgaagt
     9421 acaacttgga ttattacccg gttcaggcgg cacccagcgt ttaccgcgtc tgataggcgt
     9481 cagcacagca ttagagatga tcctcaccgg aaaacaactt cgggcgaaac aggcattaaa
     9541 gctggggctg gtggatgacg tcgttccgca atccatttta ctggaagccg ctgttgagct
     9601 ggcaaagcag gatcgtccat cttcacgccc tctacctgta cgcgagcgta ttctggcggg
     9661 gccgttaggt cgtgcgctgc tgttcaaaat ggtcggcaag aaaacagaac acaaaactca
     9721 gggtaactat ccggcgacag aacgcatcct ggaggttgtc gaaacgggat tagcgcaagg
     9781 caccagtagc ggctatgacg ctgaagcccg tgcttttggc gaactggcga tgacgccgca
     9841 atcgcaggcg ctgcgtagta tcttttttgc cagtacggaa gtgaagaaag atcctggcag
     9901 tgatgcgccg cctgcgccat taaacagcgt gggaatttta ggtggtggct tgatgggcgg
     9961 cggtattgct tacgtcactg cttgtaaagc ggggcttccg gtcagaatta aagatatcaa
    10021 cccgcagggc ataaatcatg cgctgaagta cagttgggat cagctggagg gcaaagttcg
    10081 ccgtcgtcat ctcaaagcca gcgaacgtga cagacagctg gcattaatct ccggaacgac
    10141 ggactatcgc ggctttgccc atcgcgatct gattattgaa gcggtgtttg aaaatctcga
    10201 attaaaacaa caaatggtgg cggaagttga gcaaaattgc gccgctcata ccatctttgc
    10261 ttcgaatacg tcatctttac cgattggtga tatcgccgct cacgctacgc gacctgagca
    10321 agttattggc ctgcatttct tcagtccggt ggaaaaaatg ccgctggtgg agattattcc
    10381 tcatgcgggg acatcggcgc aaaccatcgc taccacagta aaactggcga aaaaacaggg
    10441 taaaacgccc attgtcgtgc gtgacaaagc cgggttttac gtcaatcgca ttttagcgcc
    10501 ttacattaat gaagctatcc gcatgttgac cgaaggtgaa cgggtagagc acattgatgc
    10561 cgcgctggtg aaatttggtt ttccggtagg cccaatccaa cttttggatg aggtaggaat
    10621 cgacaccggg actaaaatta ttcctgtact ggaagccgct tatggagaac gttttagcgc
    10681 gcctgcaaat gttgtttctt caattttgaa cgacgatcgc aaaggcagaa aaaatggtcg
    10741 gggtttctat ctttatggtc agaaagggcg taaaagcaaa aaacaggtcg atcccgccat
    10801 ttacccgctg attggcacac aagggcaggg gcgactctcc gcaccgcagg tagctgaacg
    10861 gtgtgtgatg ttgatgctga atgaagcagt acgttgtctg gacgagcagg ttatccgtag
    10921 cgtgcgtgac ggagatattg gcgcggtatt tggcattggt tttccgccat ttctcggtgg
    10981 tccgttccgc tacatcgatt ctctcggtgc gggtgaagtg gttgcaataa tgcaacgact
    11041 ggccacgcag tatggttccc gttttacccc ttgcgagcgt ttagtcgaga tgagcaagcg
    11101 tggggaaagt ttttggaaaa caactgcaac tgacctgcaa taagaaggtc aaagctatat
    11161 gaatccgcgc tgaatggcgg agtgttgctc aaaatgtaaa cgcatattga ctatacttac
    11221 gccattgagg taaaaaacag cgtttcattc ggtgaatgga taaggcacaa tgccggccac
    11281 cgttttcttt ctctggtttc agatgaaaga aaacgggcga atctggttaa caaaagcggt
    11341 gcaatatgca agtttttatc atgcgtcacg gcgacgcagc cctcgatgcc gccagtgatt
    11401 cggttcgtcc tctgactact aacggttgtg acgaatctcg cctgatggcg aactggctga
    11461 aaggtcaaaa agtggaaatc gaacgcgttc tggtgagccc gttcctgcga gccgagcaaa
    11521 cactggaaga agtaggggat tgtctgaacc tgccttccag tgcagaagtt ctgccggagt
    11581 taacgccctg cggcgatgtt ggtctggtca gtgcctattt acaggcgttg accaatgaag
    11641 gtgttgcttc ggtactggtg atctcccact tacccttagt cgggtatctg gttgctgagt
    11701 tatgtccggg cgaaacgccg cctatgttta ccacctcggc cattgccagc gtaacgcttg
    11761 atgaaagcgg aaacggcaca ttcaactggc agatgagccc gtgtaatctg aagatggcaa
    11821 aagcgattta atacgcatgc acaaggcccg ctggtgtaat ctatcgggcc tttatttttt
    11881 tctggcaatg ttgaatttat gcaatcttat tgtactaaca atgatc
//
LOCUS       DACAOP010000121        11792 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.121, whole genome shotgun sequence.
ACCESSION   DACAOP010000121 DACAOP010000000
VERSION     DACAOP010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11792
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.121"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            208..1305
                     /gene="mltA"
                     /locus_tag="IT892_003878"
     CDS             208..1305
                     /gene="mltA"
                     /locus_tag="IT892_003878"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HAP3137031.1"
                     /translation="MKGRWVKYLLMGTVVAMLAACSSKPTDRGQQYKDGKFTQPFSLV
                     NQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGI
                     DAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGA
                     LSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDR
                     GEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRA
                     SVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIG
                     PEAGHRAGWYNHYGRVWVLKTAPGAGNVFSG"
     gene            1381..2187
                     /gene="tcdA"
                     /locus_tag="IT892_003879"
     CDS             1381..2187
                     /gene="tcdA"
                     /locus_tag="IT892_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cyclic N6-threonylcarbamoyladenosine(37)
                     synthase TcdA"
                     /protein_id="HAP3137032.1"
                     /translation="MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSW
                     AAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRV
                     TVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQID
                     PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGT
                     VCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKMMAKAARQG"
     gene            complement(2238..2681)
                     /gene="csdE"
                     /locus_tag="IT892_003880"
     CDS             complement(2238..2681)
                     /gene="csdE"
                     /locus_tag="IT892_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase sulfur acceptor subunit
                     CsdE"
                     /protein_id="HAP3137033.1"
                     /translation="MTNPQFAGHPFGTTVTAETLRNTFAPLSQWEDKYRQLIMLGKQL
                     PALPDELKAQAKEIAGCENRVWLGYTMAENGKMHFFGDSEGRIVRGLLAVLLTAVEGK
                     TAAELQAQSPLALFDELGLRAQLSASRSQGLNALSEAIIAVAKQV"
     gene            complement(2681..3886)
                     /gene="csdA"
                     /locus_tag="IT892_003881"
     CDS             complement(2681..3886)
                     /gene="csdA"
                     /locus_tag="IT892_003881"
                     /EC_number="3.13.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase CsdA"
                     /protein_id="HAP3137034.1"
                     /translation="MNVFNPAQFRAQFPALQDAGVYLDSAATALKPEAVVEATRQFYS
                     LSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPDDKTIVWTRGTTESINMVAQCYA
                     RPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGSKVVKLPLNAQRLPDVDLLPELITPR
                     SRILALGQMSNVTGGCPDLARAITFAHSAGMVVMVDGAQGAVHFPADVQQLDIDFYAF
                     SGHKLYGPTGIGVLYGKSELLEAMSPWLGGGKMIHEVSFDGFTTQSAPWKLEAGTPNV
                     AGVIGLSAALEWLADYDINQAENWSRSLATLAEDALAKRPGFRSFRCQDSSLLAFDFA
                     GVHHSDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTKSDVDALVNAV
                     DRALELLVD"
     gene            4078..4305
                     /locus_tag="IT892_003882"
     CDS             4078..4305
                     /locus_tag="IT892_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HAP3137035.1"
                     /translation="MKKTAAIISACMLTFALSACSGSNYVMHTNDGRTIVSDGKPQTD
                     NDTGMISYKDANGNKQQINRTDVKEMVELDQ"
     gene            4656..5573
                     /locus_tag="IT892_003883"
     CDS             4656..5573
                     /locus_tag="IT892_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GcvA"
                     /protein_id="HAP3137036.1"
                     /translation="MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSL
                     EDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLP
                     SFAIHWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKL
                     YAEYLLPVCSPLLLTGEKPLKTPEDLAKHTLLHDASRRDWQTYTRQLGLNHINVQQGP
                     IFSHSAMVLQAAIHGQGVALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQA
                     ELGKIAAFRQWILAKAAAEQEKFRFRYEQ"
     gene            5592..5987
                     /locus_tag="IT892_003884"
     CDS             5592..5987
                     /locus_tag="IT892_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HAP3137037.1"
                     /translation="MTSRFMLIFAAISGFIFVALGAFGAHVLSKTMGAVEMGWIQTGL
                     EYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAFVT
                     PVGGVSFLAGWALMLVGAIRLKRKGVSHE"
     gene            5980..7080
                     /gene="rlmM"
                     /locus_tag="IT892_003885"
     CDS             5980..7080
                     /gene="rlmM"
                     /locus_tag="IT892_003885"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HAP3137038.1"
                     /translation="MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIY
                     ECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGE
                     LRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYT
                     GYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDL
                     GACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVC
                     DMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINA
                     QIQARQLYHDREEVTVHVRRIWAAVGGRRDER"
     gene            complement(7124..7855)
                     /gene="fucR"
                     /locus_tag="IT892_003886"
     CDS             complement(7124..7855)
                     /gene="fucR"
                     /locus_tag="IT892_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose operon activator"
                     /protein_id="HAP3137039.1"
                     /translation="MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQT
                     QGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDAS
                     STCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
                     LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEA
                     RIGHLDEVTHIISDERQVATSLVTA"
     gene            complement(7913..8335)
                     /gene="fucU"
                     /locus_tag="IT892_003887"
     CDS             complement(7913..8335)
                     /gene="fucU"
                     /locus_tag="IT892_003887"
                     /EC_number="5.1.3.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose mutarotase"
                     /protein_id="HAP3137040.1"
                     /translation="MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIR
                     ADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDI
                     IRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP"
     gene            complement(8337..9755)
                     /gene="fucK"
                     /locus_tag="IT892_003888"
     CDS             complement(8337..9755)
                     /gene="fucK"
                     /locus_tag="IT892_003888"
                     /EC_number="2.7.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417283.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HAP3137041.1"
                     /translation="MKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENN
                     TWHQWSLDAILQRFADCCRQINSELTDCHIRGIAVTTFGVDGALVDKQGNLLYPIISW
                     KCPRTAAVMDNIEQLISAQRLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFI
                     SSLINHRLTGEFSTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIG
                     TLQNSAAAMLGLPVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSTQVDT
                     SLLSQYTGSTCELDSQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAP
                     GADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQHNLQMLEKIGHFKA
                     SELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEAR
                     AQIHYQYRYFYPQTEPEFIEEV"
     gene            complement(9864..11639)
                     /gene="fucI"
                     /locus_tag="IT892_003889"
     CDS             complement(9864..11639)
                     /gene="fucI"
                     /locus_tag="IT892_003889"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HAP3137042.1"
                     /translation="MKINTLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEK
                     LRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPT
                     RPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
                     RFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRID
                     QKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLVMAMCIRDMMQG
                     NSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVV
                     ATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLIN
                     SGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
                     LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRL
                     TGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSA
                     WAAHGMDIEGQDYRACQNYGPLYKR"
BASE COUNT         2766 a         2959 c         3138 g         2929 t
ORIGIN      
        1 ccgtggatgc gcactatact ccgctcgcgt tttcatgcaa cctttttttt aacccgatca
       61 cggattcggc atgattttga acaaaaacaa atcactaaag cctatttttt gtgcaaaatt
      121 tgcgtcaggg agaggctgct catttcatta aacgcggtgg tttgttatct tcgttgcgcc
      181 ttatttttta acctgaagaa gagaacaatg aaaggacgtt gggtaaagta ccttcttatg
      241 ggcacggttg tggcaatgct tgccgcctgc tcttccaaac caaccgatcg cggacagcaa
      301 tataaagacg ggaaatttac ccagcctttc tctctggtga accagccaga tgccgttggc
      361 gcgccgatta acgccggtga ttttgccgag caaattaacc atatccgtaa ttcgtcaccg
      421 cgtctgtatg gcaaccagag taatgtttat aacgcggtgc aagagtggct gcgcgcaggc
      481 ggtgataccc gcaatatgcg ccagttcggc attgatgcct ggcagatgga aggtgccgac
      541 aactatggta acgtgcagtt tacaggctat tacacgccgg taattcaggc gcgccatacc
      601 cgccagggcg agttccagta tcctatttac cgtatgccgc caaaacgtgg tcgtctgccg
      661 tctcgtgcgg agatctacgc gggggcattg agcgataaat acatcctcgc ttacagcaac
      721 tccctgatgg ataacttcat tatggatgtg cagggtagcg ggtatattga ctttggtgat
      781 ggcagtccgc ttaacttttt cagctatgca gggaaaaacg gtcatgcata tcgcagtatt
      841 ggtaaggtgc tgatcgaccg tggcgaagtg aaaaaagaag atatgtcgat gcaggcgatt
      901 cgtcactggg gcgaaacaca cagtgaagcc gaggttcgcg agctgctgga acagaacccg
      961 tctttcgtct tctttaaacc gcaatctttt gcaccggtga aaggggcaag tgcggtgccg
     1021 ctggttggcc gtgcttctgt tgcctccgat cgttcaatta ttccgccagg tactaccttg
     1081 ctggcagaag tgccgctgct ggataataac ggcaaattta acggtcagta cgaattgcgt
     1141 ctgatggtgg cgctggatgt cggtggcgca atcaaaggcc aacacttcga tatctatcaa
     1201 gggatcgggc cggaagccgg gcaccgcgca ggttggtaca accactatgg acgtgtctgg
     1261 gtgctgaaaa cggctccggg cgcaggtaac gtctttagcg gctgatgtga tattctgtat
     1321 gccgttttta cgtatacgac agggtgaggg ataacctcgc cctttttatt ctgaggtgct
     1381 atgtctgtgg taattagtga tgcatggcgt cagcgttttg gtggcacagc gcgtctgtat
     1441 ggtgaaaaag cgttgcaact gtttgctgac gcgcatattt gtgtggtcgg tattggcggt
     1501 gtcggttcct gggcggcgga agcgctggcg cgcacgggga ttggcgcaat cacgcttatc
     1561 gatatggatg atgtgtgcgt caccaatacc aatcggcaaa ttcatgccct gcgcgataac
     1621 gttgggctgg caaaagcgga agtaatggcg gaacgtattc gccagattaa cccggagtgc
     1681 cgtgtaacgg tggtggatga tttcgtgacg ccggataacg tagcgcagta tatgagcgtg
     1741 ggttattcgt acgtgattga tgccattgat agcgtacggc ccaaagcggc gctgattgct
     1801 tattgtcggc gcaataaaat cccgctggtc acgactggtg gcgcgggtgg gcagattgac
     1861 ccgacgcaga ttcaggttac cgatctggcg aaaacgattc aggacccgct ggcggcgaag
     1921 ttgcgcgagc gcctgaaaag cgattttggc gtagtgaaaa acagcaaagg taagctcggc
     1981 gtggattgcg tgttctctac cgaagcgctg gtgtacccgc agtcagatgg cacggtctgt
     2041 gcaatgaaag ctacggcgga agggccaaag cggatggatt gtgcatctgg atttggtgcc
     2101 gcgacgatgg tgaccgccac ctttggtttt gttgcggttt ctcatgcgct gaagaagatg
     2161 atggcgaaag cggcccgtca ggggtaaaca atcaggtcgg atgcgacgcg aacgtcttat
     2221 ccgacctggt tctgtgctta aacctgcttc gccacagcga taatcgcctc gcttaacgca
     2281 ttcaacccct ggctgcgtga ggcgctaagt tgcgcacgca atcccagctc atcaaacaat
     2341 gccagcggcg actgtgcctg caattcggcg gcggttttgc cctcaacggc agtcaacaac
     2401 accgcaagca ggccgcgcac aatgcgtcct tcgctgtcgc caaagaaatg catcttgccg
     2461 ttttcagcca tggtatatcc cagccagacg cggttttcgc atccggcaat ctctttagcc
     2521 tgcgctttta actcgtctgg caaagccggc agctgtttcc ccagcatgat caactggcga
     2581 tatttatctt cccattgcga caacggtgcg aaggtattgc gtaacgtttc tgcggttacg
     2641 gttgtgccga acggatgtcc ggcgaattgc gggtttgtca ttaatccacc aataattcca
     2701 gcgcgcggtc aacggcattc accagcgcat ccacatcact ctttgtatta tatggcgcaa
     2761 atgaggcacg cagtgtgccg gttacgccta attctgccag tagcggctga gcgcaatgct
     2821 gcccggcgcg cagggcaata ccgtactccg ccagcagcgt caccatatcg ctgtgatgaa
     2881 cgccagcaaa atcgaaggcc agcaggctgg aatcctggca gcggaatgaa cgaaagcctg
     2941 gacgtttcgc cagcgcatct tccgccagcg ttgctaagct acggctccag ttttcagcct
     3001 ggttgatatc gtaatctgcc agccattcca gcgccgcgct taatcctatg acaccagcga
     3061 catttggcgt tccggcttcc agtttccacg gcgcagattg agtcgtgaag ccgtcaaaac
     3121 tcacttcgtg aatcattttg ccgccaccca gccagggtga catcgcttcc agcagttctg
     3181 atttgccata cagcacgccg atacccgtcg ggccatacag tttgtgacct gaaaaagcat
     3241 agaaatcaat atccagttgc tgaacatccg cagggaaatg caccgccccc tgagcaccat
     3301 caaccatcac caccatcccg gctgaatgag caaaggtaat cgctcgcgcc agatccgggc
     3361 aaccgccagt gacattcgac atttgtccca gagcaagaat tcgactacga ggtgtgatca
     3421 gttctggcaa caaatcgaca tccggcagtc gctgcgcatt aagcggcaat ttcaccactt
     3481 tggatccagt ttgttgggcg accatcagcc aggggacaag gttggcgtgg tgttctgcca
     3541 cgctgacaat aatctcatcg cccggttgca gacgcggacg cgcatagcat tgtgccacca
     3601 tgttgatgga ttcagtggtg ccgcgcgtcc agacgatagt tttatcatcc ggtgcattca
     3661 gtaattgcgc cactttctct cgtgcagctt cataacgcgc ggtcaggcgt tgggcttcgg
     3721 caaactggct gcgatggacg tttccggcgc tcaggctgta aaactgtcgg gtggcttcaa
     3781 ccacggcttc aggtttaagc gcggtcgcgg cgctgtcgag atagacgccc gcatcctgta
     3841 gtgcgggaaa ctgggcgcga aactgcgcgg gattaaaaac gttcatggta ctcctcggct
     3901 tgatgcaccg atcgtgacgc aaaattcact ttgatacaag gagagtgcta accatcagaa
     3961 ttatctggat atcctggcga agccgcgtca gtaacatatg ctgaatagtg ttaggcgtta
     4021 attttagcct gttaatcaat gctattaaga tttattaatc gctttaagga gaagatgatg
     4081 aaaaagactg ccgcaattat ttctgcctgt atgctgactt ttgccctgag cgcctgttcc
     4141 ggttcgaact atgtgatgca caccaatgac ggacgtacca tcgtctctga cggcaaacca
     4201 cagactgata acgataccgg tatgatttcg tataaagacg ctaatggcaa caaacagcag
     4261 atcaaccgta ctgacgtgaa agagatggtc gaactggatc agtaattcgc gatcgcaagg
     4321 taaaaaaaag caccgcaatt aggcggtgct acattaatca ctatggacag acagggtaaa
     4381 tgtacaggaa gtgaaaaaag gtagctttgc taccatggtc tgaatcgcag accaattgca
     4441 aacacaacaa cacaacatca caaccgtaag ccaaaagttc accagaacac gcattccgat
     4501 aaaacttttc gttccggctc aggaagtgcc gccactatag gtatttgctg gtagaagctc
     4561 aacggacaat ttataatggc tcagattaaa aaaactaata ggttacacag tgtgatctaa
     4621 ttgttaaatt catttaacat caaagtttaa aagccatgtc taaacgatta ccaccgctaa
     4681 atgccttacg agtttttgat gccgcagcac gccatttaag tttcactcgc gcagcagaag
     4741 agctttttgt gacccaagcc gcagtaagtc atcaaatcaa gtctcttgag gattttttgg
     4801 ggctaaaact gttccgccgc cgtaatcgtt cactcctgct gaccgaggaa gggcaaagct
     4861 atttcctcga tatcaaagag atattttcgc aattaaccga agcgacgcgt aaactccagg
     4921 cccgtagcgc caagggggcg ttgacggtca gtttactccc cagtttcgcc attcattggt
     4981 tggttccgcg actttccagc tttaattcag cttatccggg aattgacgtt cgaatccagg
     5041 cggttgatcg tcaggaagat aagctggcgg atgatgttga tgtggcgata ttttatggtc
     5101 ggggcaactg gccggggcta cgggtggaaa aactttacgc cgaatattta ttgccggtgt
     5161 gttcgccgct actgctgact ggcgaaaaac ccttgaagac cccggaagat ctggctaaac
     5221 atacgttatt acatgatgcg tcacgccgtg actggcagac atatactcgc caattggggt
     5281 taaatcatat caacgttcag caagggccaa tttttagcca tagcgccatg gtgctgcaag
     5341 cggctattca cgggcaggga gtggcgctgg caaataacgt gatggcgcaa tctgaaatcg
     5401 aggccggacg tcttgtttgc ccgtttaatg atgttctggt cagtaaaaat gctttttatc
     5461 tggtttgtca tgacagtcag gcagaactgg gtaaaatagc cgcctttcgc caatggatcc
     5521 tggcgaaagc cgctgctgaa caagaaaaat tccgctttcg ttatgaacaa taatttacgt
     5581 agggtacgac catgaccagc cgttttatgc tgattttcgc cgccattagc ggcttcattt
     5641 ttgtggctct gggcgctttt ggcgcgcatg tgttaagtaa aaccatgggg gccgttgaga
     5701 tgggctggat ccagaccggt ctcgaatacc aggcgttcca cacgctggcg atcttaggtc
     5761 tggcggtggc aatgcagcgt cgcatcagta tctggtttta ctggagtagc gttttcctcg
     5821 cgttaggcac ggtgctgttc agcggcagcc tttattgcct ggcgctgtcc catctgcgtt
     5881 tgtgggcatt tgtcacaccg gttggcggcg tgagcttcct cgcgggctgg gcgttaatgt
     5941 tagttggtgc tatccgttta aagcgcaagg gcgtaagtca tgaataaggt tgtattgctg
     6001 tgccgtccgg gctttgaaaa agagtgcgcc gcagaaatta ccgataaagc cggccagcgg
     6061 gaaattttcg gttttgcccg cgtgaaagag aatgcgggtt atgtcattta tgaatgttat
     6121 caacctgatg atggcgataa gttaatccgt gagctgccgt tcagttcatt aatttttgcc
     6181 cgccagtggt ttgtggtggg ggaactcctg cagcatttgc cgccagaaga tcgtattacc
     6241 cccattgtcg gcatgttaca gggtgtagta gagaagggcg gtgaactgcg tgttgaagtt
     6301 gccgatacca acgaaagcaa agagttgctg aaattctgcc gtaaattcac cgtgccgcta
     6361 cgcgctgcct tgcgcgatgc gggtgtgctg gcgaactatg aaacgccgaa gcgtccggtt
     6421 gtgcatgtat tctttattgc accaggctgc tgctataccg gttactcata cagcaacaat
     6481 aattcgccgt tctatatggg cattccgcgc ctgaaatttc cggcagatgc gccgagtcgt
     6541 tccacgctca aactggaaga ggcatttcat gtgtttattc ctgcggatga gtgggatgaa
     6601 cgcctggcga acgggatgtg ggcggtggat ttaggcgctt gcccaggcgg ctggacctac
     6661 caactggtga agcgcaacat gtgggtttat tccgtcgaca acggcccgat ggcgcaaagt
     6721 ctgatggata ccggacaggt gacgtggctg cgggaagacg gtttcaaatt ccgtccgaca
     6781 cgcagcaata tctcctggat ggtatgcgat atggttgaaa aaccggcgaa agttgcggca
     6841 ttgatggcgc agtggctggt taatggctgg tgccgtgaaa ccattttcaa cctcaaactg
     6901 ccgatgaaaa aacgctacga agaagtgtca cacaatctgg cgtatattca ggcacagctt
     6961 gatgaacatg gcataaatgc tcagattcag gcgcggcagt tgtatcacga tcgcgaagaa
     7021 gtgacggtgc acgtccgccg tatctgggct gcggtgggtg gtcgtcgcga cgagcgataa
     7081 caggcaaggc cggggcgtcg tctccggcct gctacccttt ccgtcaggct gttaccaaag
     7141 aagttgcaac ctggcgctca tcagaaataa tgtgcgttac ctcatccaga tgcccgatgc
     7201 gggcttcccc tgaacgatta aatttacttt tatcaatcaa taacaacgat tgcgcggcgc
     7261 gttttaatag cattgatttg taatcagcgt tgatggcatt ggagtcccac agtgcgccgc
     7321 tgctatcgat cccttcacaa gaaaaaataa acagatcgat ttccagcgat ttaagttggg
     7381 aaatcagcga gggattgacg taacagccat atttgcgctc aagtgtgcca ccggaactga
     7441 tcagttgaat gcgttcgcgt ttaccgagtt catggcaaat cggatggcta ttggtgaaga
     7501 cctgaatgtt gatgtcaggc aactggcgtg ccagatacca gcaagttgaa ctggcgtcta
     7561 aggctatcac catcccttct tcaatccacg cgagcgcctc gcgcgcgata tctgctttat
     7621 gcgcataatg gcttttcagc cggatgtgaa agggatcgcc actgtcttga ttttgacggt
     7681 ggatatattt agcgcgtcca tgattgcgca gaattttacc ctgcgtctgt aattcattga
     7741 gatcgcgacg aatggtttct ttactgacct ttagctgttc agagagagct tccgtggtca
     7801 ggctggtatg gttcagcagc aggtcgacta tcgcttgctg gcgtgccgct ttcatatttt
     7861 tcaccccatc attcgataac cgcccgcgtc atgcgggcgt accggtatga gattacggtg
     7921 ttaccccttt ttttaaaaga atattcccgt acttcgctcg ttcgcctgtg ataacgatcg
     7981 caaaggcttt ttgtgcccgt tcataaaacg caaaacgatt gatgcggatg atgtcaggac
     8041 acggggcttg tagtgaaagc gcattacggt aacgtcgttc tacttcagga tcgagagtgt
     8101 caccttctac cgccgccatc atcaccagcg gcggtgcata actgtccagt tcaaataatg
     8161 ggataatcgc ctggagcaag tcgctcacca acaggccatc agcgcggatc acctgcggtc
     8221 ccatcgaatg ggcgggaaag tgagcatcgg aaaaaataat ttcatctcca tgtcccatct
     8281 ctgccagcac tttcaatagt tcgggagaaa ttaacggcga aattgttttc agcatttcac
     8341 acttcctcta taaattcagg ttcagtttgc gggtagaaat aacggtactg ataatgaatc
     8401 tgcgcgcgag cttcctccgg gctgttaaat tcccctacgc cataccaacc gaacagcgca
     8461 gctcctgcga cggtcgtttc ggcgtcgtcg agaactttta ccggaatatc aagcatattg
     8521 gctttaatct gattccacaa tgtgttgcga cttcctccac cgactaacaa taattcagag
     8581 gctttaaagt gcccgatttt ttccagcatc tgtagattgt gctgtaattg cgcagttaac
     8641 ccttccagcg ccgcgcgata gaaatgcccc cgcgtggtat taagcgtcac tccttgccag
     8701 ccagcgttct gacacgacaa taaatcacac tgcattttca cgccatccgc gccaggcgcg
     8761 atcagacgag cctcttcaat caacatttgc cagggagttt cagccgtcca gaacagtttt
     8821 ctcacccatt ccagcacgcc ggatgccagc cattgcatac ctgggttata caaccctgcc
     8881 tgactatcca gttcgcaggt cgaaccggtg tactgactta acagcgaagt atcaacctgg
     8941 gtgctacgga ccattaaaat ttcccatgta ccggaagaga gcacgggttc attttgttcg
     9001 gcaccagcgc caaaaagggc gaactgggta tcgtgacctg cggaaatcac cggtatgcca
     9061 acgggtaagc cgagcattgc tgcggcgctg ttctgtaacg taccaatctg ttcacccgct
     9121 tccaccagac gagggaagag tcggcgtgga ataccggtgg cttgtaaaat ttgcggactg
     9181 aaatcgcgtt gctggatatc cagcatctgg ctggttccgg ccatcgtgat atcagtagag
     9241 aattcgccgg ttaaacggtg gttaatcagc gacgaaataa agagccaggc gtgcgcgcgt
     9301 tccagcagtt gtggatgatt ttctttcaac cacaccaact tatataacgt attgaaacta
     9361 aaggctccga cgccagaaat agcctgcaac cgctgtgcgg agatcaactg ttcaatattg
     9421 tccataaccg ctgctgttcg cggacatttc cagctaatga tcggatagag cagattgcct
     9481 tgcttatcta ccagagcgcc atccacacca aaggtggtga cggcgatacc gcggatgtgg
     9541 caatcagtca gttcactatt gatttgccga cagcaatcag caaagcgttg caaaatggcg
     9601 tctaaagacc actggtgcca ggtgttgttt tccatcgcga tatcgctggc attaggcgtt
     9661 gaggcgcggg caacaatttt tccctgccga ttaaccgcga tggccctgac attggtcgcg
     9721 ccacagtcga gtaccaggat aacttcttgt ttcataatcg ctcctgcaat atagccggat
     9781 aacattgttt atccggctaa ccactcttgc ttgttctggc ccggtagccg gagcgaccgg
     9841 gcatcacatc agggagtaat gtattaacgc ttgtacaacg ggccgtagtt ctggcaagcg
     9901 cggtaatcct ggccttcaat atccatgccg tgcgcggccc aggcagaagg acgatatact
     9961 ttggtctctt caacgttgtg catacatacc gggatacgca gcatggaggc gagagtgata
    10021 aagtctgcgc caacgtggcc gatggtcaga accccgtggt tagcgcccca gttcgccatt
    10081 accgaataca catccgtaaa cggcccttta ccggtgaggc gcggtgcaaa ccaggtggtt
    10141 ggccaggttg agttggtgcg tttgttgagg atgtcatgca catccttcgg taactcaacg
    10201 ctccagcctt ccgcgatttg cagtaccggg cccaggcctt tgatgatgtt gacacgggtc
    10261 atggtgaacg ggacgccgcc ttcggtaagg aagcgggaag agtaaccgcc gccacggaag
    10321 tattcgtgga tcgccgggca ccattcggta gcggcgaggc aagcgtcagc ctcttgctga
    10381 gagatttccc agtgtggctt catcgtcggg ttaccttcgc tgtcgcgttg tttacaggaa
    10441 ccgtccagcg cagcagaacc ggagttgatc aaatggatga tgccgtgttc tgccagtcca
    10501 tccagtttat gccccgttac acgttcaatt gcttctggtg accagtaggt acgcacatcg
    10561 gcaaatacct gagcggtgcc ggtgagctgg tgacccatta gcattgccac gccgttaaga
    10621 ctgtcgtttt cggtcgccac gacaaagggt tcgcgcacgc cattccagtc aaatgaactg
    10681 ttaaggatcg cttcggcggt gtcgccattg ggatattgat cggtccagtg acgttgcccc
    10741 tggaagcccg cagcgatggc gttgtagcca agtgattctt ccacgcgacc aatatcggcc
    10801 agtttgctgt tgccttgcat catgtcgcgg atacacatcg ccatcactaa actttcgcgc
    10861 agaactgcgc ggctttgctc ggcattgcgt tgatactgtt tgttattttc atcttcgcca
    10921 tagcggaagt ttttatcagc ccaggccagc gccatttcca gttcggcttc gtcgtaaatc
    10981 ttctgatcga tacggcgacg cagttcggtc atatccaccg cctggacttt cattcccagc
    11041 caggattcaa agaagttgtg atcaacaatg gaaccggcga tacccatcga aacgccgccc
    11101 agcgacagat agcttttacc tttcatgctg gcgacggcca aaccggcgcg ggcaaagcgc
    11161 agcagttttt cttcaacatc agcaggaatc gatgtgtcat cggcatcctg aacgtcatga
    11221 ccgtaaatgg agaatgccgg gatgcctttc tggctgtgag ctgccagagc cgcagccagg
    11281 taaacagcgc cggggcgttc agtgccgtta aagccccaaa tggctttcgg gcgggttgga
    11341 tccatgtcga tggtttcact gccatagcac cagcaaggcg ttaccgtaat ggtgaggcct
    11401 acattctggc tgctgaattt ttcttcgcaa gcagcggctt cagccatacc cgcgatacag
    11461 gtatcggaaa tgacacactc gacggcagct ccgcaggcat ggcgcagttt ctcggtcagc
    11521 agtgcagccg tggctttcgc catattcatt gtttgttctt caagcgactc acgaacaccc
    11581 atgcgacgac cgtcaataac cgggcggata ccaattttcg gtaacgtatt aattttcatc
    11641 aggattcctc atctcgcttt attggcgctc tgctaaggcg gagaaaggaa accaccgaag
    11701 cagtagtatt ggtcattact tgctaactcg agttagctta ggtttgtagg ctttttatgc
    11761 acaacttttt tgttgttgaa atgtgagggg ct
//
LOCUS       DACAOP010000122        11460 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.122, whole genome shotgun sequence.
ACCESSION   DACAOP010000122 DACAOP010000000
VERSION     DACAOP010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11460
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.122"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(731..1300)
                     /locus_tag="IT892_003890"
     CDS             complement(731..1300)
                     /locus_tag="IT892_003890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137043.1"
                     /translation="MSGNIGANPVPKLPLLAEWVDKNNDDLFVKAKSEKKERTVKKLK
                     NRGLATTLARINTWIDYDDDDNYKWVTEYYLSPVSIESLLTCSYNLITVQAKSKHPNI
                     NSTKLYILPFLSKTRLVILSCMAFYKPSSWDSEVLIDNNIKWTPHIIELITSNDIKKH
                     LTDLAKNFENETLYPILKAFKLLPDSDKK"
     gene            complement(1285..2558)
                     /locus_tag="IT892_003891"
     CDS             complement(join(1285..2198,2198..2558))
                     /locus_tag="IT892_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611435.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP3137044.1"
                     /translation="MIVLILVFRLVIGEQMIDVLGPEKRRRRTTQEKIAIVQQSFEPG
                     MTVSLVARQHGVAASQLFLWRKQYQEGSLTAVAAGEQVVPASELAAAMKQIKELQRLL
                     GKKTMENELLKEAVEYGRGKKVDSARALIARGWGVSLVSRCLRVLRAQLYVILRRTDD
                     WMDGRRSRHTDDTDVLLRIHHVIGELPTYGYRRVWALLRRQAELDGMPAINAKRVYRI
                     MRQNALLLERKPAVPPSKRAHTGRVAVKESNQRWCSDGFEFCCDNGERLRVTFALDCC
                     DREALHWAVTTGGFNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQF
                     ARMLGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNE
                     WHPHSALGYRSPREYLRQQASNGLSDNRCLEI"
     gene            2604..3362
                     /locus_tag="IT892_003892"
                     /pseudo
     CDS             2604..3362
                     /locus_tag="IT892_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001218737.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            3520..4530
                     /locus_tag="IT892_003893"
     CDS             3520..4530
                     /locus_tag="IT892_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP3137045.1"
                     /translation="MSLKAIATALGVSVTTVSRALGGYADVSASTRARVEAEARRRGY
                     RPNTQARRLKTGKTDAVGLVYPGRDVPFNSGVFMDMVSCISRELAHHDIDLLLIADDE
                     HADCHSYMRLVESRRVDALIIAHTLDDDPRITHLHKAGIPFLALGRVPSGLPCAWFDF
                     DNHAGTGQATQKLIALGHKRIALLSEDTSHTYVIARRQGWLDALNEHELEDTWLRLVS
                     PTRRAGYQAVMELMSLPIPPTAIITDNDLSGDGAAMALQLSGRLSGKAAVSLVVYDGL
                     PQDSIIELDVAAVIQSTRSLVGRQISEMIYQIITDSSSKPLQVVWNPVFYPGKTIHSP
                     CS"
     gene            4626..6752
                     /locus_tag="IT892_003894"
     CDS             4626..6752
                     /locus_tag="IT892_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001706555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP3137046.1"
                     /translation="MVSKYCRLSSPRSDLIIKTHPHAEIIWWGSALKHFSPDDCASLE
                     RPVANGRLDIDTPLTLMAENALGLFSSPGLEGHRNGLDSSPVFYTVDVEHTENTLRLT
                     SEDSVAGLRLVSELVMTPSGILKVRHALTNLREGDWQINRFAITLPLAERAEEVMAFH
                     GRWTREFQPHRVRLTHDAFVLENRRGRTSHEHFPALIVGTPGFSEQQGEVWAVHLGWS
                     GNHRMRCEAKTDGRRYVQAEALWMPGEKALRKNETLYTPWLYACHSADGLNGMSQQYH
                     RFLRDEIIRFPEQKPRPVHLNTWEGIYFNHNPDYIMQMAERAAALGVERFIIDDGWFK
                     GRNDDRAALGDWYTDEQKYPNGLMPVIKHVKSLGMEFGIWVEPEMINPDSDLFRLHPD
                     WVLSMPGYSQPTGRYQYVLNLNIPEAFAYIYERFSWLLGEHPVDYVKWDMNRELVQAG
                     HEGRAAADAQTRQFYRLLDLLRERFPHVEFESCASGGGRIDFEVLKRTHRFWASDNND
                     ALERCTIQRGMSYFFPPEVMGAHIGHRRCHATFRQHSIAFRGLTALFGHMGLELDPVA
                     ADAKESDGYRRYALLYKEWRQLIHTGVLWRVDMPDPSIQVQGVVSPDQSQALFMISQL
                     AMPDYTLPGILRFPGLAAEVRYRLRVIDHPDLQVVGEGGHTMRKLPVWMNQSLEASGE
                     WLAQGGIQLPVLDPESAILIALERAV"
     gene            6815..8092
                     /locus_tag="IT892_003895"
     CDS             6815..8092
                     /locus_tag="IT892_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3137047.1"
                     /translation="MNSASTHKNPDFWIFGLFFFLYFFIMATCFPFLPVWLSDVVGLS
                     KTDTGIVFSCLSLFAISFQPLLGVISDRLGLKKNLIWSISLLLVFFAPFFLYVFAPLL
                     RFNIWAGALTGGVFIGFVFSAGAGAIEAYIERVSRSRGFEYGKARMFGCLGWALCATM
                     AGMLFNVDPSLVFWMGSGGALLLLLLLFLARPSTSQTAMVMNTLGANSSLISTRMVFS
                     LFRMRQMWMFVLYTIGVACVYDVFDQQFATFFRSFFDTPQAGIKAFGFATTAGEICNA
                     IIMFCTPWIIHRIGAKNTLLVAGGIMTIRITGSAFATTATEVVILKMLHALEVPFLLV
                     GAFKYITAVFDTRLSATVYLIGFQFSKQLAAILLSTFAGHLYDRMGFQNTYFVLGMIA
                     LTVTVISAFTLSSSRGSVHPSVEKAPAAHSEIN"
     gene            8092..9522
                     /locus_tag="IT892_003896"
     CDS             8092..9522
                     /locus_tag="IT892_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP3137048.1"
                     /translation="MKQRLALAQSALEKLCARRGNAWYPIFHLAPPAGWMNDPNGLIY
                     FNGRYHAFFQHHPASAYQGPMHWGHATSTDMLHWQHEPVALAPGDKYDRDGCFSGSAV
                     DDDGVLSLIYTGHICLEDRGNDSIIREVQCLATSHDGIHFEKQGCVLTPPEGIMHFRD
                     PKVWHEEGSWWMVIGARDASDNGQVLLYRGTSLRDWHLEHVLAHSAAGESYMWECPDF
                     FRCGNFHWLMFSPQGMTPSGYRFRNLFQSGVLAGSWKPGSVFALKGGFEELDYGHDFY
                     APQSMLAEDGRRIIMAWMNMWDSPVPTRSEAWAGCLTLPREVFERDGRLCQRPVREVE
                     SLRRKCQPLSPVRLQGLQLLTENVQAAELLVTWHTVDSHAEHYGVRLGDGLRLYVDNQ
                     AGRLVLWRYYPEEGLDGYRSVELPDTEYLTLRIFLDRSSVEVFVNDGEATLSSRIYPQ
                     ADSRQLSLYAAHGDAILTNGTLWMLT"
     gene            9717..11111
                     /locus_tag="IT892_003897"
     CDS             9717..11111
                     /locus_tag="IT892_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HAP3137049.1"
                     /translation="MNKLLLGLSVFLLLEYNACAAKTGGLTLEQRMALLEERLEAAEK
                     RAEKAERMLKSFDTEQHSEIRQISSEQNKKAANSYAVVESTKEKTSSPGFLLSGYNDL
                     KFYGDVEFNIDAASKPGQLVMISSGANSESVNERWDLNGRILLGFDGTRKLDNGYFAG
                     FSAQPLADMHGSVNIDDALFFFGKDDEWKVKVGRFEAYDMFPLNQDTFIEYSGNTAND
                     IYADGRGYIYMMKEGRGRSDAGGNFLISKQLDNWYFELNTLLEDGTSLYNNGNYHGRY
                     MEQQKNVAYLRPVIAWSPTEEFTVSAAMEANVVKNAYGYTDNKGNFVDQSNRSGYGIS
                     MTWNDLKTDPENGIVVTLNTAYLDASNEKDFTASINALWKRFELGYIYAHNKIDEFSG
                     VVCNNGCWIDGEGIYNIHTIHASYQFANVMDMENFNIYLGAYYSILDSNCRYSNCDIT
                     DDRYGARLRFKYFF"
     gene            complement(11357..>11460)
                     /locus_tag="IT892_003898"
     CDS             complement(11357..>11460)
                     /locus_tag="IT892_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HAP3137050.1"
                     /translation="LCTLGDTPGQIFRSMVDGYHRHCTAPRGDKPTV"
BASE COUNT         2803 a         2566 c         2829 g         3262 t
ORIGIN      
        1 gatacagcca caacctgccg cactgactgt ccagggtaaa tgaacagccc acaaaatttt
       61 ttacccaaaa cccggtaaaa aattttgcgt tctgcccagg acaggtgcgt caggccgtgg
      121 cagtgatgcc ccttgcggcg agggttctca aacaggtgat ggtgaatacc agagggaaca
      181 aaaggcaggt ccccgcaaaa cgtcaaaact gcggctcccg aaactcaaca gctaccgtgt
      241 tctgtcaaga aaaaatcgct taaattcagt cgtacagccc ttaagtactg ccagcaggct
      301 tgtcagtacc aagtttccga tactgcgcgg ctacgctaac ggggttaaaa gggcttactt
      361 atactacatc atcgctgaaa gcttgtatgg tttcgcggaa cagggagtaa caggagaata
      421 ttcactctct accggctaac agttagctta attgcagtaa ctggtaacca actgctagaa
      481 aaattcacca tgaataataa ttgtgctgat tacctgcaat tattgtagtg aaatttctgt
      541 tcatattttt tcgctagcga tgtcttgttt gagaaaaaac actatttgtt gaatagtttg
      601 attctggtat ttggagtctt ttaaaggggg attctatatg gatatcactt tttatatgtt
      661 gtaaataatg ccgctgtaga agaacaacgg caaatgaagg ggggtattgt tacaataatc
      721 ttatttgtct ctatttttta tccgaatcag gtagcaattt aaaagctttc aatatggggt
      781 aaagtgtttc attctcaaag ttttttgcta aatcagtgag gtgttttttg atgtcattgc
      841 tggtaatgag ctcaattatg tgaggagtcc atttgatatt attgtcaatc aacacttcag
      901 agtcccaact agatggttta taaaaagcca tgcaagataa aataactagt ctcgtcttcg
      961 ataagaatgg taatatatat agtttggtac tgtttatgtt agggtgtttt gattttgcct
     1021 gcacagtaat taagttatat gagcaagtta gtaatgactc aatactaaca ggcgataagt
     1081 aatattctgt aacccacttg taattgtcat catcatcata atcaatccac gtatttatcc
     1141 tggctaaagt tgttgctagg cctctgtttt ttagtttctt tacagtcctt tcctttttct
     1201 cagatttggc ttttacgaat aaatcatcat tatttttatc aacccactca gccaggagag
     1261 gcaatttagg aactggattt gcccctatat ttccagacac ctgttatcac ttaacccatt
     1321 actggcctgc tgccgcagat attcccgtgg cgagcgataa cccagtgcac tatgcggatg
     1381 ccattcgtta taatgctcga acgcctctgc aaggttcttt gctgccgtta acccgtctgg
     1441 tttgggcatg atactgatgt agtcacgctt tatcgttttc acgaagctct ctgctattcc
     1501 gttactctcc ggactccgca ccgccgtgtt cttcggttca agtcccaaca tccgggcgaa
     1561 ctggcgtgtt tcattagccc ggtagcatga accattatcc gtcagccact ccactggaga
     1621 cgacggaaga tcgttgccga agcggcgttc caccgctccc agcatgacgt cctgtactgt
     1681 ttcactgttg aagccgccgg tagtgaccgc ccagtgcagt gcctcacgat cacagcagtc
     1741 cagcgcgaac gtgacacgca gtctctctcc gttatcacag cagaactcga acccgtcaga
     1801 gcaccatcgc tgattgcttt ctttcacggc cactctgcct gtatgtgccc gtttcgatgg
     1861 cggtacagca ggttttcgct caagcaacag cgcattctgg cgcatgatcc ggtaaacacg
     1921 tttggcattg atcgcaggca taccatcaag ttctgcctgt ctgcgaagca gcgcccatac
     1981 ccgacgataa ccatacgtgg gcagctctcc gataacatgg tgtatacgga gaagcacatc
     2041 cgtatcatca gtgtgacgac tgcggcggcc atccatccag tcatcggttc gtctgagaat
     2101 gacgtacaac tgcgcacgca acacccggag acaacggctg actaagctta ctccccatcc
     2161 ccgggcaata agggcgcgtg cgctatccac ttttttgcac gcccgtattc aacggcttct
     2221 ttaaggagtt cattttccat cgtttttttg ccgagcaggc gctggagttc tttaatctgc
     2281 ttcatggcag cagcaagttc agaggcagga acgacctgct ctcctgcggc cacagcagta
     2341 agacttccct cctggtattg cttgcgccag agaaataact ggctggctgc cacaccgtgt
     2401 tgccgggcaa caagggagac cgtcattccc ggttcaaaac tctgctgaac aattgcgatc
     2461 ttttcctgtg tagtacgccg tctgcgtttc tccggtccta agacatcaat catctgctct
     2521 ccaatgacta gtctaaaaac tagtattaag actatcactt atttaagtga tattggttgt
     2581 ctggagattc agggggccag tctatcctcc cgctggaaat gctggaaatt ctgcgccgca
     2641 tagaaaaacg tggctcgctg gaaaaactgc gtaaggtccg ccaatactgt aatcagattt
     2701 ttcgttatgc tatcgccacc ggacgagcca ctgtcaatcc ggcatctgaa ctgaccagta
     2761 cgctggcggc accaaaagct gcgcatttcc cccacctgag agcagatgag ctccctgttt
     2821 ttctccggaa gctcgctgaa tatcatggca gtcctgttac ccgcatggcg acaaatcttc
     2881 tgcttctgac gggtctcaga accattgagc tacggtccgc tgaatggtca gaaattgatt
     2941 ttgataatgc cctgtggaca atccctgaaa gccgcatgaa aatgcgacgt aaacatgtcg
     3001 taccactgtc acgacaggcc actgacattc tgctgcagct caaaactttc tccgagcaat
     3061 accgactggt ttttccggga cgttgtgata tcaacaagcc aatgagcgaa gccagcatca
     3121 atatggtgct caaacgtatc ggttacgatg gcagggcaac cggtcatggt tttcgtcaca
     3181 ccatgagtac cattctgcac gaacagggct ttaattctgc ctggattgaa atgcagttag
     3241 ctcatgtgga taaaaattcc atcaggggta cctataatca tgccctgtat ctcgatggtc
     3301 gccgtgaaat gatgcaatgg tacgctgact acattgattc actttccagc caggagagtt
     3361 aattacactt tgtcctgaaa ttattctcac aatcaataac ctttccctct gatcttacag
     3421 atcagaggga ttccgttaac ttacaataag tgatattggt tgtctggaga ttcagggggc
     3481 cagtctaacg gtctactata ataattagca ggagataata tgtcacttaa ggcgattgcc
     3541 actgcactcg gagtttctgt caccactgtc agtcgggctc ttggaggcta tgcagatgtg
     3601 tcagcttcca cccgtgcacg ggtggaagct gaagctcgtc gacgcggcta ccgtcctaat
     3661 actcaggcaa gaagactcaa aaccggtaaa accgatgctg tcggtctggt ttatcctgga
     3721 cgtgatgtgc catttaacag tggtgttttt atggatatgg tcagttgcat cagccgggaa
     3781 cttgctcacc atgatattga cttactactg atagctgatg atgagcatgc cgattgccac
     3841 agctatatgc ggcttgttga aagtcgcagg gttgatgctc tcatcattgc acacactctg
     3901 gatgacgatc cccgtatcac acaccttcat aaagcaggta ttccatttct ggctcttggt
     3961 cgggtaccat ctggtctgcc ctgtgcgtgg tttgactttg ataatcatgc cgggactgga
     4021 caggcaaccc agaaactgat tgctttggga cataaacgta ttgcattgtt gagtgaagac
     4081 acttcacata cctatgttat tgcaagacgt cagggatggc ttgatgcact gaatgagcat
     4141 gaactggaag atacatggct gcggctggtt tctcccacac ggcgagcagg atatcaggcc
     4201 gtgatggagt taatgtcact accgatacca ccaacagcta ttattactga caatgatctg
     4261 agtggagatg gtgctgccat ggcgctgcag ttgagcggtc gtctttcagg aaaagctgcg
     4321 gtatctctgg ttgtatatga tggtttgcca caggacagta ttattgagct ggatgtagct
     4381 gcagttattc agtcaacacg aagcctcgtt ggtcgccaga tttccgagat gatatatcag
     4441 ataattactg attcatcatc aaaaccacta caggttgtct ggaacccggt attttatccg
     4501 ggaaagacga ttcattctcc ttgctcctga tttttttatc cagctcacat atccgaaacg
     4561 ttttggttga tacccgaaac gtttcggatc aacagtaagg catccctgag aaaggagaat
     4621 gtcttatggt ttcaaagtac tgcagactga gcagtcctcg ctctgattta attattaaaa
     4681 cccatccaca tgcagaaatt atctggtggg gctctgcact gaaacatttc tcaccggatg
     4741 actgtgccag cctggaaaga ccggttgcga atggtcgtct ggatattgat acgccactga
     4801 cactgatggc tgaaaatgcc ctgggacttt ttagctctcc gggactggaa ggacacagga
     4861 atgggctgga ttcatctcct gttttttata cagttgacgt ggaacatacc gaaaacactc
     4921 tgagacttac cagtgaagat tcggtagccg gcctgcgtct ggtcagcgag ctggtgatga
     4981 cgccatcagg aattctgaaa gttcgtcatg cactgaccaa cctcagagag ggggactggc
     5041 agataaatcg tttcgccatc actttacctt tagcggagcg tgcggaagaa gtcatggctt
     5101 ttcacggacg ctggactcgt gaatttcagc cgcacagggt acgtctcact catgatgctt
     5161 ttgttctgga aaatcgcaga gggcggacat ctcatgagca ttttccggcg ctgattgtcg
     5221 gcacgccagg cttctcggaa caacagggag aggtatgggc tgtgcatctg gggtggagtg
     5281 gaaatcaccg tatgagatgt gaggcaaaaa ctgacggcag gcgttacgtt caggctgagg
     5341 ctctgtggat gccgggtgag aaggctctca ggaagaatga aaccctgtac accccgtggc
     5401 tatatgcctg ccactctgcg gatggcctga atggaatgag tcagcaatac catcgttttt
     5461 tgcgtgatga aattatccgt ttccctgagc aaaaaccccg ccccgtacat ctcaatacct
     5521 gggaaggtat ttatttcaat cacaatcctg attacatcat gcagatggct gagcgtgcag
     5581 cagcactggg cgttgaacgt ttcattattg atgatggctg gtttaaagga cgtaacgatg
     5641 accgcgcggc tctgggcgac tggtataccg atgaacagaa atacccgaac gggctgatgc
     5701 cggttattaa acatgtgaaa tctctcggta tggaatttgg catatgggtt gagccggaaa
     5761 tgattaaccc ggattctgac ctgtttcgtc ttcatcctga ctgggtattg tcaatgcctg
     5821 gatattccca gccaaccgga agatatcagt atgttcttaa cctgaatatt cctgaggcct
     5881 ttgcttacat ttatgaacgt ttctcatggt tactgggaga acatccggtt gattatgtga
     5941 aatgggacat gaatcgtgag cttgtacagg cagggcatga aggccgtgcg gcagcagatg
     6001 cacagacccg tcagttctat cgattgcttg atctcctccg tgaacgtttt ccacatgttg
     6061 agtttgagtc ctgtgcttcc ggtggggggc gtattgactt cgaagtcctg aaacgcacac
     6121 accggttctg ggcatctgac aataatgatg ccctggagcg ctgcaccata caacgtggca
     6181 tgagttactt tttccctcct gaggtgatgg gggcacatat tggccatcgc cgctgccatg
     6241 caactttccg acagcacagc atcgcttttc gtgggctgac agcattgttc ggccatatgg
     6301 ggctggagct ggatccggtg gccgcagatg cgaaggaatc tgacggttat cgccggtatg
     6361 ccttgctcta taaagaatgg cgacaactga ttcatacagg tgttctctgg cgtgtggata
     6421 tgccagatcc ttcgatacag gttcagggag tcgtcagccc tgatcagtct caggcacttt
     6481 ttatgatcag ccagcttgca atgccggatt acaccttacc aggcatactt cgttttcccg
     6541 gtctggcggc ggaagtgcgt taccggcttc gggttattga tcacccggac ctccaggtgg
     6601 tcggtgaagg cggtcatacc atgcgcaaat tacctgtctg gatgaatcag agccttgagg
     6661 ccagtggtga atggctggca cagggaggga ttcagctccc cgtactggat ccggagagtg
     6721 cgattttgat agcacttgaa agagctgtgt gaagagaggt acggagcctc agctccgtcc
     6781 tgtttctcaa tattatcccg tgagggtaag aataatgaat tctgcaagta cgcataaaaa
     6841 tcccgatttc tggattttcg gtctgttctt ctttctctac tttttcatca tggcaacctg
     6901 ttttccgttt ttgcctgtat ggctgtccga tgtggtcggg ctgagtaaaa cggatacagg
     6961 tatagtcttt tcatgtcttt ctctgtttgc catcagtttc cagccattgc ttggggtcat
     7021 atcagatcgc ctgggactga aaaaaaacct gatctggagt atcagcctgt tactggtatt
     7081 tttcgccccc ttttttttat atgtatttgc gcccctgctg cgcttcaata tctgggcagg
     7141 cgcactgact ggcggtgttt ttattggttt tgtgttttct gcaggtgccg gagctattga
     7201 agcttatata gagcgggtca gtcgcagtcg tggatttgaa tacggtaaag cgaggatgtt
     7261 cgggtgtctg ggctgggcgt tatgtgcgac tatggctgga atgcttttta atgtcgatcc
     7321 ttctctggtt ttctggatgg ggtcaggagg cgcattattg ttgcttcttc tgttgtttct
     7381 ggcgcgcccc agtaccagcc agacggcaat ggttatgaat acactgggtg ccaattcttc
     7441 cctgatttcg accagaatgg tcttcagcct gtttcgcatg cgtcagatgt ggatgtttgt
     7501 tctctacacg attggtgtgg cctgtgtcta tgatgtattt gatcagcagt ttgccacatt
     7561 ttttcgttca ttctttgaca ctcctcaggc aggaataaaa gcattcggat ttgctaccac
     7621 tgcgggggag atttgtaatg ccattatcat gttctgtaca ccatggataa ttcatcgcat
     7681 tggtgccaaa aataccctgc ttgttgcggg gggaattatg accatccgca ttaccggttc
     7741 tgcttttgcc accaccgcga cagaagtggt gattctgaaa atgcttcacg ctcttgaagt
     7801 tccatttttg ctggttgggg cgttcaaata tattacggca gtgtttgaca cccgactgtc
     7861 agcgaccgtt tatttaatag gttttcagtt ttccaaacaa cttgctgcaa tacttctctc
     7921 tacctttgcc ggccacctgt atgatcgtat gggattccag aatacgtatt ttgtgctcgg
     7981 gatgattgct ctgactgtta ccgtgatatc agctttcacg ctgagttctt cccgcgggag
     8041 cgtacaccct tctgtagaaa aagcccctgc agcgcattcg gagattaact gatgaaacag
     8101 cgtcttgctt tggcacagtc cgcccttgaa aaactttgcg cacgtcgtgg taatgcctgg
     8161 tacccgattt ttcatctggc tccacctgcc ggctggatga atgatccaaa tggccttatt
     8221 tacttcaatg ggcgttacca tgcgttcttc cagcatcatc ctgcaagcgc atatcagggg
     8281 ccaatgcact gggggcatgc caccagtacc gacatgttgc actggcaaca cgaacctgtc
     8341 gcgctggcac ccggagataa atatgatcgt gatggctgtt tttcagggag tgccgtggat
     8401 gatgatggcg tgctatcact tatttatact ggtcatattt gtctcgaaga tcgtggtaat
     8461 gacagcatta tccgtgaagt acagtgtctg gctaccagtc atgatggtat tcactttgag
     8521 aagcagggct gtgtgctgac acctccggaa ggtatcatgc atttccgtga tcccaaagtc
     8581 tggcacgaag aaggctcctg gtggatggtc attggtgccc gggacgcttc tgacaatggg
     8641 caagttctgt tgtatcgcgg gacatctttg cgggactggc atctggagca tgttctcgct
     8701 cattccgcag ccggagaaag ttatatgtgg gaatgccccg atttcttcag gtgtggtaat
     8761 tttcactggc tgatgttctc accacagggg atgacccctt ccggttatcg gttccgtaac
     8821 ctttttcaga gcggtgtgtt ggcagggagc tggaagcctg gttctgtctt tgcgctgaaa
     8881 gggggatttg aagagctgga ttatggtcat gacttttatg ctccacagtc catgctggct
     8941 gaggacggca ggcgtatcat tatggcatgg atgaatatgt gggattcacc cgtgcccacc
     9001 cgcagtgaag cctgggcagg atgtctgacg ctgcccagag aggtttttga gcgcgatggc
     9061 cggctgtgcc agcgacctgt gcgtgaagtc gaatctctgc gcagaaaatg ccagccatta
     9121 tcccctgtaa ggttacaggg tttgcaatta ctgaccgaaa atgtacaggc cgcagaatta
     9181 ttggtgacgt ggcatacggt tgacagtcat gcggagcact atggcgtccg ccttggagac
     9241 ggtctgcgac tttatgtgga taatcaggcc ggacgactgg tactgtggcg ctattaccct
     9301 gaggaagggc tggatggtta ccgcagtgtt gaacttcctg atacagaata tctgactctt
     9361 cgtattttcc tggatcgttc atctgttgaa gtgtttgtta acgatggtga ggcaacctta
     9421 tcaagtcgta tttatccgca agcggactcg agacaattat cgttatatgc cgctcatggc
     9481 gatgcgatat taactaatgg cactttatgg atgctgacct gagatatatc gatatcagta
     9541 ttttttttga tattatctgt cattactttg ccagtacaca ttaattatct ttgctgtgtg
     9601 cttttggtaa tgtgttgcga ttatatatac cagtctggtg aagagtatga atggtatttt
     9661 gtgttgatac agagaatata agagtaccca catttgtttt tatttaaggg ggtaaaatga
     9721 ataagttact cttgggtttg tctgtttttt tattactgga atacaatgcg tgtgcagcaa
     9781 aaacaggggg gctaacgctt gaacaaagaa tggcattgct ggaagaacgc ctggaagctg
     9841 cagaaaaaag ggcggaaaaa gcagaaagaa tgttaaaaag ttttgataca gaacaacatt
     9901 ctgaaatacg tcaaattagt tcagagcaga ataaaaaagc tgctaacagc tatgcagtag
     9961 ttgagtcaac aaaagaaaaa acatcttctc caggttttct gctctctggt tacaatgatt
    10021 tgaagtttta tggtgatgtg gagtttaata tagatgctgc cagtaaaccc ggtcagttag
    10081 taatgataag ttccggggcg aacagtgagt cagtgaatga acggtgggac cttaatggcc
    10141 gtattctatt aggttttgac ggtacccgta agcttgataa tggttatttc gctggatttt
    10201 cagcacaacc actggcggat atgcacggtt cagtgaatat tgatgatgca ttattctttt
    10261 ttggaaaaga tgacgagtgg aaagtgaaag tcggtcgttt tgaagcttac gatatgttcc
    10321 ctctaaatca ggatactttc attgagtatt ccggtaatac agctaacgat atttatgctg
    10381 atggccgtgg ttatatctat atgatgaaag agggacgcgg tcgttctgac gctggtggta
    10441 atttcctcat cagtaaacaa ctcgataact ggtattttga gttaaacacg ttacttgaag
    10501 acggaacatc tttatataat aacggtaatt atcatggacg atatatggag cagcagaaaa
    10561 atgtcgctta tctgcgcccg gtaattgcct ggtcgccaac ggaagaattc acagtctccg
    10621 cagcgatgga agcaaacgtg gtaaaaaatg cttatggcta taccgataat aaggggaatt
    10681 ttgtcgatca gtccaatcgt tccggttatg gtattagcat gacatggaac gatctgaaaa
    10741 cagatccgga aaatggcatc gtggttactc ttaataccgc ctatttggat gccagtaatg
    10801 agaaagattt cactgccagt attaatgctc tgtggaaacg tttcgaactg ggttatatct
    10861 acgcacataa taagattgat gaatttagtg gtgtcgtgtg taataatggt tgctggattg
    10921 atggtgaagg aatatacaac attcacacca ttcatgcatc ttatcagttt gctaatgtga
    10981 tggatatgga gaactttaat atttacctcg gggcttatta ctcaattctg gatagtaact
    11041 gtagatatag taattgtgac attaccgatg atcgttacgg tgcccgatta cgtttcaaat
    11101 actttttttg atgcatagta acaaagtatt gttccacact tacattaacg cgtttttcgg
    11161 gtacaccatc ggtgagcata cgaataatcg ctgtctgtcg atggttgatt taatttattg
    11221 cgcaacgagc cagctaccgg gaactggctc tgaagttgcg tcaggtcacg aagtactgcc
    11281 cggggaataa tgccagacta actctgacca gtgccacttg acgtctccgc cagcgcagcg
    11341 gaggcaaata gtactgtcag accgtgggct tatccccgcg cggagcggta caatgacggt
    11401 gataaccgtc aaccatactg cgaaatattt gccccggcgt gtcacccaga gtgcacagat
//
LOCUS       DACAOP010000123        11248 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.123, whole genome shotgun sequence.
ACCESSION   DACAOP010000123 DACAOP010000000
VERSION     DACAOP010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11248
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.123"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..134)
                     /locus_tag="IT892_003899"
     CDS             complement(<1..134)
                     /locus_tag="IT892_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP3137051.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     R"
     gene            complement(205..2319)
                     /gene="fusA"
                     /locus_tag="IT892_003900"
     CDS             complement(205..2319)
                     /gene="fusA"
                     /locus_tag="IT892_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020455498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP3137052.1"
                     /translation="MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVH
                     DGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKT
                     RLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEW
                     HQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQ
                     AMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLT
                     FFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTD
                     EESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQ
                     SGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPL
                     AGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETP
                     EENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTM
                     EFLKYDEAPSNVAQAVIEARGK"
     gene            complement(2416..2886)
                     /gene="rpsG"
                     /locus_tag="IT892_003901"
     CDS             complement(2416..2886)
                     /gene="rpsG"
                     /locus_tag="IT892_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006714698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAP3137053.1"
                     /translation="MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVY
                     SALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMR
                     WIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW"
     gene            complement(2983..3357)
                     /gene="rpsL"
                     /locus_tag="IT892_003902"
     CDS             complement(2983..3357)
                     /gene="rpsL"
                     /locus_tag="IT892_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003852912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAP3137054.1"
                     /translation="MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DCSGVKDRKQARSKYGVKRPKA"
     gene            complement(3483..3770)
                     /gene="tusB"
                     /locus_tag="IT892_003903"
     CDS             complement(3483..3770)
                     /gene="tusB"
                     /locus_tag="IT892_003903"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HAP3137055.1"
                     /translation="MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYL
                     ESLRNAPIKVYALNEDLIARGLTGQISNDIILIDYTDFVRLTVKHPSQMAW"
     gene            complement(3778..4137)
                     /gene="tusC"
                     /locus_tag="IT892_003904"
     CDS             complement(3778..4137)
                     /gene="tusC"
                     /locus_tag="IT892_003904"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusC"
                     /protein_id="HAP3137056.1"
                     /translation="MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGV
                     FQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLE
                     ADALRRELANYDVILRF"
     gene            complement(4137..4523)
                     /gene="tusD"
                     /locus_tag="IT892_003905"
     CDS             complement(4137..4523)
                     /gene="tusD"
                     /locus_tag="IT892_003905"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusD"
                     /protein_id="HAP3137057.1"
                     /translation="MRFAIVVTGPAYGTQQASSAFQFAQALIADGHELSSVFFYREGV
                     YNANQLTSPASDEFDLVRAWQQLNAQHGVALNICVAAALRRGVVDETEAGRLGLASSN
                     LQQGFTLSGLGALAEASLTCDRVVQF"
     gene            complement(4523..5245)
                     /locus_tag="IT892_003906"
     CDS             complement(4523..5245)
                     /locus_tag="IT892_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP3137058.1"
                     /translation="MSRSLLTNETSELDLLDQRPFDQTDFDILKSYEAVVDGLAMLIG
                     SHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFT
                     RAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMSTFVPPETPDVGSSVNFA
                     SSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI
                     SKHTVYLYIRQFKSGDFQGQDK"
     gene            complement(5412..6224)
                     /gene="fkpA"
                     /locus_tag="IT892_003907"
     CDS             complement(5412..6224)
                     /gene="fkpA"
                     /locus_tag="IT892_003907"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003827768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HAP3137059.1"
                     /translation="MKSLFKVTLLATTMAVALHAPITFAAEAAKPATAADSKAAFKND
                     DQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTL
                     QAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGEA
                     PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLV
                     IPPELAYGKAGVPGIPPNSTLVFDVELLDVKPAPKADAKPEADAKAADSAKK"
     gene            6445..6663
                     /locus_tag="IT892_003908"
     CDS             6445..6663
                     /locus_tag="IT892_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein SlyX"
                     /protein_id="HAP3137060.1"
                     /translation="MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDH
                     LRLLTEKLKASQPSNIASQAEETPPPHY"
     gene            complement(6712..7302)
                     /gene="slyD"
                     /locus_tag="IT892_003909"
     CDS             complement(6712..7302)
                     /gene="slyD"
                     /locus_tag="IT892_003909"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP3137061.1"
                     /translation="MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISG
                     LETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQ
                     GPVPVEITAVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHH
                     DHDHDGCCGGHGHDHGHEHGGEGCCGGKGNGGCGCH"
     gene            complement(7397..7597)
                     /locus_tag="IT892_003910"
     CDS             complement(7397..7597)
                     /locus_tag="IT892_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheV family putative metal-binding protein"
                     /protein_id="HAP3137062.1"
                     /translation="MAIRKRFIAGAKCPACQAQDSMAMWRENNIDIVECVKCGHQMRE
                     ADKEARDHVRKDEQVIGIFHPD"
     gene            complement(7607..9412)
                     /gene="kefB"
                     /locus_tag="IT892_003911"
     CDS             complement(7607..9412)
                     /gene="kefB"
                     /locus_tag="IT892_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefB"
                     /protein_id="HAP3137063.1"
                     /translation="MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGP
                     WGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALL
                     AGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV
                     IPALALVPLLAGSADEHFDWMKVGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFT
                     AATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFI
                     SVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGG
                     EFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDE
                     KPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGD
                     ATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELL
                     QAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADT
                     VQISRAREARRELEEIFQREMQQERRQLDGWDEFE"
     gene            complement(9412..9963)
                     /gene="kefG"
                     /locus_tag="IT892_003912"
     CDS             complement(9412..9963)
                     /gene="kefG"
                     /locus_tag="IT892_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312229.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein KefG"
                     /protein_id="HAP3137064.1"
                     /translation="MSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHY
                     PDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAG
                     KYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSA
                     QELASHARAYGDWLANPLSPGGR"
     gene            10094..>11248
                     /locus_tag="IT892_003913"
     CDS             10094..>11248
                     /locus_tag="IT892_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP3137065.1"
                     /translation="MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLL
                     ALLKNEISADGGSYTFPGSWQLAWVNQETPALPQAALEYVIDGDREYRQLEAQLHDAN
                     ERNDGHAIATIHGKLDAIDAWSIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNL
                     AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIH
                     IEQQSMFEYTGNYSSFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQA
                     QSRIKMLERMELIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGDRIILDSIKLN
                     LVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQL"
BASE COUNT         2759 a         3086 c         2716 g         2687 t
ORIGIN      
        1 cgagcagcac cgccgtaggt tttagccagt acggtggtga ttgcagcggt cagagtagtt
       61 ttaccgtggt caacgtggcc gatagtacca acgttaacgt gcggttttgt acgttcaaat
      121 ttttctttag acacggctat attccttact atagtgctct ccccttcagg agagagcacg
      181 ggactttggt attaaccctt aggcttattt accacgggct tcaattacgg cctgagcaac
      241 gttactcggc gcttcatcat acttcaggaa ttccatagtg tatgatgcac gacctttggt
      301 cagagaacgc agctgagttg cgtatccgaa catttcagac agcggtactt cagcgtggat
      361 cttaacgcca gtaacttcag attcctgacc tttgagcata ccacgacgac ggctcaagtc
      421 accgataacg tcaccggtgt tctcttccgg agtttctact tcaaccttca tgatcggctc
      481 aagcagaact ggtttcgctt tcttaaagcc ttctttaaag gcgatagaag cagccagttt
      541 aaacgccagt tcagaggagt caacgtcatg gtaagaaccg aagtgcagac gaatacccat
      601 gtctactacc gggtagcctg ccagcggacc tgctttcagc tgttcctgga tacctttatc
      661 aacggccggg atgtattcgc cagggattac accaccttta atgtcgttga tgaactcgta
      721 gcctttcggg tttgaacccg gctccagcgg gtacatgtcg ataacaacat gaccatactg
      781 accacgacca ccagactgtt tcgcgtgttt accttcaaca tcggtaactt tctggcggat
      841 agtttcacgg taagcaacct gcggtttacc tacgttcgct tcaacgttga attcacgctt
      901 catacggtca acgatgatgt cgaggtgcag ttcgcccata cccgcgatga tggtctggtt
      961 agattcttcg tcagtccata cacggaaaga cgggtcttct ttagccagac ggcccagagc
     1021 cagacccatt ttttcctggt cagctttggt tttcggttca actgcgatgg agattaccgg
     1081 ctcagggaat tccatacgtt ccagaatgat cggcgcatcc gggtcacaca gggtgtcacc
     1141 agtggttacg tctttcagac cgatagcagc agcgatgtcg cccgcgcgaa cttctttgat
     1201 ctcttcacgt ttgttagcgt gcatctgaac gatacgaccg aaacgctcac gtgcagcttt
     1261 cacggagttc agtacggtat caccagagtt aaccacaccg gagtaaacac ggaagaaggt
     1321 caggttacca acaaacgggt cggtagcgat tttgaacgcc agtgcagaga acggctcgtc
     1381 atcacttgcg tgacgttcag ccggagtgtc tttaccgtcg tccaggatac cgttgatcgc
     1441 aggtacgtca accggggatg gcaggtaatc aattaccgca tccagcatcg cctgaacacc
     1501 tttgttcttg aacgcagaac cacaggttac caggatgatt tcgttgttca gaacgcgctg
     1561 acgcagagca cctttgattt ctgcttcagt cagttcttca ccacccaggt atttttccat
     1621 cagctcttca gaagcttcag ctgcggattc gatcaggttc tggtgccatt cgttagccag
     1681 ttcaaccatg tctgccggga tatcttcgta ttcgaaggtt acgccctggt cagcgtcgtt
     1741 ccagttgata gctttcattt tcaccaggtc aacaacaccg gtgaaatgtt cttcagcacc
     1801 aatcgccagc tgcagcggaa ccgggttcgc gcccagacgg gttttgatct ggttaacaac
     1861 tttcaggaag ttcgcaccca tgcggtccat tttgttaacg aacgcaatgc gcggaacttt
     1921 atatttgttt gcctgacgcc atacggtttc agactgcggc tgaacaccac caactgcgca
     1981 gtaaaccatt accgcaccat cgagaacacg catggaacgt tctacttcga ttgtgaagtc
     2041 aacgtgcccc ggggtgtcga tgatgttgat gcgatgcggc tcatactgct tagccatacc
     2101 agaccagaat gcagtagtcg cagcggaagt gatggtaata ccacgttcct gctcctgctc
     2161 catccagtcc atggttgcag cgccgtcatg aacttcaccg attttatggt ttacaccggt
     2221 gtagaacaga atacgttcgg tagtagtggt tttaccggcg tcgatgtgcg cactgatacc
     2281 gatgttacgg tagcgtgcga tgggtgttgt acgagccatt tgtttcctcg tttatctttt
     2341 aggcgttcaa tttaagtagc ccaaagcggg ctgcttactg gaagcgcccg cctggtgact
     2401 aaaactccga agggattacc aacggtagtg tgcgaacgcc ttgttggctt cggccatacg
     2461 gtgaacgtct tcacgtttct taactgcagt acctttgttt tctgcagcat cagaaagttc
     2521 gttcgccagg cgcagagcca tggatttatc accgcgttta cgagcagctt caacgatcca
     2581 acgcattgcc agagcattac gacgaaccgg acggacttca actggtacct gataagtaga
     2641 accaccaacg cggcgagact taacttctac agtcgggcgc acgttttcga gagctacttc
     2701 gaatgcttcc agttcagatt taccagagcg ctgagccagg gtctccagcg cgctgtatac
     2761 gatagattca gcagtagatt ttttaccatc taccatcagg atatttacaa atttagccag
     2821 cagttctgat ccgaacttcg gatccggcag aattttacgc tgaccaatga cgcgacgacg
     2881 tggcatggaa atactccgtt gttaattcag gattgtccaa aactctacga gtttagtttg
     2941 acatttaagt taaaacgttt ggccttactt aacggagaac cattaagcct taggacgctt
     3001 cacgccatac ttggaacgag cctgcttacg gtctttaacg ccggagcagt caagcgcacc
     3061 acgtacggtg tggtaacgaa cacccgggag gtctttaaca cgaccgccac ggatcaggat
     3121 cacggagtgc tcctgcaggt tgtgaccttc accaccgatg taggaagtca cttcgaaacc
     3181 gttagtcaga cgaacacggc atactttacg cagcgcggag ttcggttttt taggagtggt
     3241 agtatataca cgagtacata cgccacgttt ttgcgggcat gcttccagcg caggcacgtt
     3301 gcttttcgca actttgcgag cacgtggttt gcgtaccagc tggttaactg ttgccattaa
     3361 atagctcctg gttttagctt ttgcttcgta aacacgtaat aaaacgtcct cacacaatat
     3421 gaggacgccg aattttaggg cgatgccgaa aaggtgtcaa gaaatataca acgatcccgc
     3481 catcaccagg ccatctggct ggggtgctta accgtaagtc tgacgaaatc agtatagtca
     3541 atgagaatga tgtcgttcga aatttgacca gtcaaaccgc gggcaataag gtcttcgttc
     3601 agggcataga ccttaatggg ggcattacgc agactttcaa ggtagcggtt accgtcaact
     3661 gcggcagtta cgccatcttg caataatagc agttcgtctc cttcactgag cagacgcagc
     3721 agcgcagcaa aatccgtcag ccagggtgag cgatgtaatg tgtgcagcat aaacgcctca
     3781 aaacctcaaa ataacatcgt agttggcgag ttcgcggcgt aaggcatctg cttcgagcgg
     3841 cgtggcttcg acaacaaagg gtgtctgcgg atctaacccg cgttcgcgca gtgaagccgc
     3901 acaaacccag cactgttcaa tgtcgtacag acccaacaat ttaaaagtgg caatgtaatc
     3961 acgcgccagc actgcatcgg gcttttgtcc tggcagcagc tgaaaaacgc catcagctat
     4021 aaagaagaca gccagatcgt cagttaatgc ggaagttgcc agtaaagcat ctaaaccttc
     4081 ccggcctgcg gctgtaccat gaggtgcagt agaaaaaaca aacgcaattc gtttcatcag
     4141 aactgtacca ccctgtcaca ggtcagcgag gcttccgcca gcgccccaag tccgcttaag
     4201 gtaaatccct gctgaaggtt tgacgaagcc agacccagtc ttccggcctc cgtttcatca
     4261 acaacgccac ggcgtaatgc tgccgctacg cagatattca gcgccacacc atgttgcgca
     4321 ttcagttgtt gccaggcccg tacgaggtca aattcgtcac ttgccggaga ggtcaattgg
     4381 ttagcgttat agaccccttc ccgatagaaa aagacgctgc ttaactcatg gccatctgct
     4441 atcagcgcct gcgcaaactg aaaagcacta ctcgcctgtt gcgtaccgta tgctggcccg
     4501 gtcaccacga tggcaaaacg cattacttat cttgcccctg gaaatcaccg ctcttgaact
     4561 ggcggatgta gagatagaca gtgtgtttgg agatgttcag gcggtcagca acctggttga
     4621 tcgcatcttt aatatcgaag atccctttct cgtagagatt cagcacgatc tgacgatttt
     4681 tggcgttatt agaaacattg cgatcggcat tcacttcttc gatggtgaac tccagcgttt
     4741 gggtaaccag atcttcaaca gaagaggcaa agttgacgct tgaaccgaca tccggggttt
     4801 ctggcggcac aaaggtgctc ataatctgcg agaagggaac atcaagattc atattgatgc
     4861 acagcagacc aattacacgc tgttcgcggt tacgaatcgc gatagtcagg gacttcatta
     4921 atacgccgct tttggcgcga gtaaagtagc atttagaaac gctgctatcc gctcccgtca
     4981 tatcgtgcag catacgtagc gccaggtcag taattggcga accaatcttc cggcctgtat
     5041 gttcaccgtt agcaatgcga atggctgaac attttagatc ctgcaaagag tgcaaaacga
     5101 tttcacagtg ggagccaata agcatcgcta acccgtccac caccgcttcg taggatttca
     5161 gaatatcaaa atcggtctgg tcgaaaggac gttgatccag taaatccaac tcactggttt
     5221 cgttggttaa aagcgacctg gacatgaaaa aaaacactcc ttttcaggag cctgtcgtta
     5281 acttttcagg gcaggctcat taatgatgcg ggtaactaaa ttaatacagc ggaggttccg
     5341 ctttccagca ctaattatat ccggcctgta ataaaaaaac cgccgcctgg tcaggcggcg
     5401 gttcttaatg cttatttttt agcagaatct gcggctttcg catcagcttc cggctttgca
     5461 tcagccttcg gcgctggttt cacatccagc agctctacgt caaacaccag ggtagaattc
     5521 ggtgggatcc ccggaacacc cgctttgccg taagccagtt ctggtggaat aaccagtttg
     5581 atcttaccgc ctttcttgat gttcttcaga ccttctgtcc aacccgggat aacaccgtcc
     5641 agacggaaag aaagcggttc accacgggtg taagagttgt cgaactcttt accgtcgatc
     5701 agcgtacctt tgtagttcac tacaacagta tcgctgtctt tcggtgcttc gcctttaccg
     5761 gcttctacta cctgataaac cagaccagtt gaagaggttt tcacaccttt ctctttggca
     5821 aatttctcgc ggtactcttt accttttgct tcgttatcag ccgcgtcttt ttccatcttc
     5881 gcctgagcag aagacttcac gcgagcttcg aatgcttgta gagtctgttc gatctcttgg
     5941 tcggagagtt tgctcttatc agcaaatgca tcctgaacac cagcgatcag ctgatcttta
     6001 tccagtttga tgcccagttt ttcttgttct tttagagagt tttccatgta acgacccagc
     6061 gaggcaccca gtgcataagc tgatttctga tcgtcatttt tgaacgctgc tttgctgtca
     6121 gcagctgtag caggttttgc agcttcagca gcaaaagtga ttggtgcatg cagggcaacg
     6181 gccattgtgg tcgccagcag cgttacttta aacagtgatt tcatccatat ctccaggatc
     6241 ggggcatctc accccagggt taactattat cagaagggta ctataaagcg ttgtcgaaca
     6301 aatctacata cagacacgcc ctattatcat ctattttcag actctttttg tttaaattag
     6361 tttcgatgac cgcgaaatga gtgctgtctc gggcagcaaa gttaagtaga atccgcggcg
     6421 accattcgac aaaagaggtg aatcatgcag gatttatcat tggaagcacg cctggcagag
     6481 ctggagagcc gactggcttt tcaggaaatc accattgaag aactgaacgt cacggtgacc
     6541 gctcatgaaa tggagatggc gaaactgcgc gatcatctgc gtctgctgac cgagaagtta
     6601 aaagccagcc agccgtcgaa catcgcgtcg caggctgaag aaacgccacc gccacattat
     6661 tgaggcgtaa aaaaagcggg gattccccgc ttttttgtca ctttttcggt attagtggca
     6721 accgcaaccg ccgttgcctt taccgccaca gcagccttcg ccaccgtgtt catgaccgtg
     6781 atcgtggcca tgaccgccgc agcaaccgtc gtggtcgtga tcgtggtggt gatcgtgcgc
     6841 gccgtgaacg tgaccatgag ccagttcttc ttcagtcgct tcgcgaatcg ccacaacttc
     6901 aacgttgaat ttcaggttct gaccggccag catgtggtta ccatcaacca cgacgtgatc
     6961 gtcttcaacc gcagtgattt caaccggtac cggaccctgg tcggtttcag ccaggaaacg
     7021 catacctacc tgcagttcat caacgcccat aaatacgtct ttaggaacac gttgcaccag
     7081 gttttcgtcg tactgaccgt aagcgtcgtt cgcgccaaca gcgacatcaa atttgtcgcc
     7141 aacttcatga ccttccagcg ccgtttccag gccagagatc agggaaccgt gaccatgcag
     7201 gtagtccagc ggcgcactca ccggagactc atcaaccaac acaccgtctt ctgtacgtac
     7261 ctgataggcc aggctgacca ccaggtcttt tgctactttc atgatatctc ctgagcatgg
     7321 gaagaatagt ggcgcagatt gtagcggaat tctgcagccg tgtactcact agcttaaaaa
     7381 aactcggcgc atatcgctag tccggatgaa aaatcccgat cacttgctca tctttgcgaa
     7441 cgtgatcgcg ggcttctttg tctgcttctc gcatctgatg tccgcactta acacattcaa
     7501 caatatcaat attattttcg cgccacatcg ccattgaatc ctgcgcctga caggccgggc
     7561 attttgcgcc cgcaataaaa cgttttcgga ttgccatctt taccctctac tcaaattcat
     7621 cccagccgtc cagctggcgt cgttcttgtt gcatttcacg ctggaaaatc tcttccagtt
     7681 cgcgtcgggc ttccctggcg cgagaaattt gtacggtatc ggcatgcatt gggatgagct
     7741 ctcgcagcat ccgcatatcc aggcggcgaa aatgcagttg cgctcgctgt gcctgatgcg
     7801 gatgcatgcc aagcgtgacc agcgtcttgc gccccagctc taacgcactg gagaatgttt
     7861 cacgggaaaa ctgcgtcacc cctgcctgta ataactcatg cgcttccaca cgtccgcgcg
     7921 ctcgcgcaag aatatgcaaa tgcggaaagt gctgttggca tatttccacc agcttcatgg
     7981 tgtcttccgg ctcgttacag gtaatgacga tagactcagc ggcctctgca cccgcagaac
     8041 gtaaaagatc gacctgcgtg gcgtcgccgt aataaacttt gtagccgtat ttacgcatca
     8101 ggttaacggc gctgatatcc cgctccagca cggtaatgcg cattttattt gccatcagca
     8161 aacgaccaat cacctgacca aaacgcccga agcccacgac aatgacctgg ggtttatcat
     8221 cgttgaccca cggtttttcg tcttcttctt ccggtccgtt aaactggcgg gatagccatt
     8281 tatccaccag cttcatcagc aacggcgtgg tcatcatgga aagcgtcacc gtcaccagca
     8341 acaacgccat ctggtcgccc tggaataagc gttgtgaaga agcggtagaa aagaggacaa
     8401 aggcaaactc accaccctga ctcaacacgc cagcaaactg catccgctct gagctacgca
     8461 cgccatacaa tcgcgccagc agatacagca cgagaatttt caccgccacc agcacaacca
     8521 cgcttatcac tacccacaac agatgggtat aaagcacccc gaggttgagt gacatgccga
     8581 cagagataaa gaacaaaccg agcagcaagc ctttgaaggg atcgatagcc gtttccagtt
     8641 catggcgata ttcactttcc gccagcagca cgcccgcaat aaatgtaccg agcgccatcg
     8701 acagccccag cgcatccata aacaatgcgg aacccaacac cagcagcagc gtcgcggcgg
     8761 tgaacacttc ccgcacgcca gaagctgcaa taaagcggaa taccggacgc agtaaatagc
     8821 gcccaccaat cagcatgccg acaaacgcca gcaccttcat gccgaccttc atccagtcga
     8881 aatgttcgtc tgccgacccc gccaacaacg gcactaacgc cagtgctggg attactgcca
     8941 gatcctgaaa cagcagaacc gaaaacccga gctggccgga ttcgctgcga ttcatccctt
     9001 tctcacgcat caattgcaac gccattgcag ttgaagacat cgcaaggcca atgccaccga
     9061 ccaccgccgc ctgccaggcg aaatccgtca gcatcaataa tcccgccagc aacgccgcgc
     9121 ttaacagcac ctgtgccgcg cctacgccaa aaatcgaacg ccgcagttgc caaagtttgg
     9181 agggattcaa ctcaaggccg atgataaaca tcaggaatac cacgccgagt tccgaaaagt
     9241 ggaggatctc atcgacgtcg ctaataaacc ccagccccca cgggccaatt gcaatccctg
     9301 ccagcaaata tcccaacaca gcgccaatac ccagccgcga tgccagcggc accgcagcca
     9361 ccgccgcgaa gagaaacagc actcctgcga gtaaaaaatc ggaaccttcc atcagcggcc
     9421 tcctggagac agcggatttg ccagccagtc accgtaggct ctggcgtggc tcgccagctc
     9481 ctgtgcgctt tgccgtctcg cccagtaaat aatgatggga cttaaccaat gcatccggca
     9541 catgcccgcc gccagttcaa aggggcgcag cacatcgctc atcgggtagc gattcagcgc
     9601 gtcataacgg taagcacttt ccggctcgcc ggtggtaatc acgctacgcc agtactttcc
     9661 cgccagttgg tttcctcccg gcccgctggc aaaaccacga cttaataccc ggtccagcca
     9721 ctctttcagt agcgccgggc agctataggt ataaagagga tgctgaaaga caatcacctc
     9781 gtgctcgcgc agtaatgcct gctcacgggg gatatcaata aaaaaatcgg gatagtgcgc
     9841 gtaaaggtcg tgcacggtaa cattgctgag ctgcgtggcc ggtttaagca gtacccggtt
     9901 tgccaccgag tcctgagatt ccggatgggc atacagcagc aaaactttcg ctggctgaga
     9961 catcatcccc ctcccggtat ggtttttgtg tatagtcgct gttttgggct accattgcgc
    10021 ccggtgcggc agctcgccca tacattacat tatcataatg ataagttaac atagtctgaa
    10081 catacggcac cttatgattg ttttctcctc gttacaaatt cgtcgcggcg tgcgcgtcct
    10141 gctggataat gccaccgcca ccatcaaccc tgggcagaaa gtcggcctgg tgggtaaaaa
    10201 cggctgtggt aaatctaccc tgctggcatt gctgaaaaat gaaatcagcg ccgacggcgg
    10261 cagctacacc tttccgggaa gctggcaact ggcgtgggtg aatcaggaaa cgccggcgtt
    10321 accgcaagcg gcgctggaat atgtcattga cggcgaccgt gaatatcgtc aactagaagc
    10381 gcagctacac gacgccaacg aacgtaacga cgggcacgcc attgcgacca ttcatggcaa
    10441 gctggatgct attgacgcat ggagtattcg ctcccgtgct gccagcctgc tgcacggcct
    10501 cggtttcagc aatgaacaac tggagcgccc ggtaagtgat ttttccgggg gctggcgtat
    10561 gcgtcttaac cttgcccagg cgctgatttg ccgttcagac ttgctgctgc tcgacgaacc
    10621 gactaaccac ctcgatctcg atgccgttat ctggctggaa aaatggctga agagctatca
    10681 gggcacgctg atcctgatct ctcacgaccg cgacttcctc gatccgatcg tcgataaaat
    10741 tattcatatc gaacaacaaa gcatgttcga gtacaccggc aactacagtt cgtttgaagt
    10801 acagcgcgcc acccgtctgg cgcagcaaca agcgatgtac gaaagccagc aggaacgcgt
    10861 agcgcatctg caaagttata tcgaccgttt ccgtgccaaa gccaccaaag cgaagcaggc
    10921 ccagagccgc attaagatgc tcgagcgtat ggagctaatt gcccccgcgc acgtcgacaa
    10981 cccgttccgc tttagcttcc gcgcgccgga aagcctgcca aatccgttac tgaagatgga
    11041 aaaagtcagc gcgggctatg gcgatcgcat tattctcgac tcgattaaac tgaacctggt
    11101 gcccggctcg cgtattggtc tgttaggccg caatggcgcg ggtaaatcga cattaatcaa
    11161 actgttagcc ggtgaacttg cgccagtcag cggtgaaatt ggtctggcga aagggatcaa
    11221 actcggctac ttcgcccagc atcaactt
//
LOCUS       DACAOP010000124        11141 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.124, whole genome shotgun sequence.
ACCESSION   DACAOP010000124 DACAOP010000000
VERSION     DACAOP010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11141
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.124"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(1..1099)
                     /locus_tag="IT892_003914"
                     /pseudo
     CDS             complement(1..1099)
                     /locus_tag="IT892_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002441793.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
     gene            complement(1554..2486)
                     /locus_tag="IT892_003915"
     CDS             complement(1554..2486)
                     /locus_tag="IT892_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HAP3137066.1"
                     /translation="MELLSYISKGLFLSEEEAKRYIVTIPRRYKIYPIAKRNGNGYRL
                     IAQPARQVKALQKVVINHMLANLKVHENAFAYEADKSIRSNALMHCNNDYLLKMDFKN
                     FFMSIKPHNLLSVLKDYGVELTDTDIFVLKNLFFWKLRRNSPLRLSVGAPSSPIISNT
                     VMYFFDEEISKRCKDLGITYSRYADDLTFSTKVKGALFDVPKLVREVLNVVNLRNIKI
                     NHEKTVFTSRKFNRHVTGVTITTDGYLSLGRDRKRLLRSKIHYYVCGVLSEKEILTLK
                     GELGYAKFIEHKFFASMIKKYGDDVISEISKYEI"
     gene            complement(2488..3456)
                     /locus_tag="IT892_003916"
     CDS             complement(2488..3456)
                     /locus_tag="IT892_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000993028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137067.1"
                     /translation="MNALQEQFGDLKYSNFTVQFMPPIIFVCGGPINSTPMSVRDHIF
                     TYVAGHKPELSDSLILAENFHDYFREGAYSDLMSFEDDIANISTLVVICLESAGSLVE
                     LGLFVNRKSLAQKLHVVAPFEEIEGNERKNIPARSSFIYLGPLEYLKKIDEASVSVYP
                     WPKSDRMKYDEVELIYHDIHSRLKRVKKTERYNPENTGHLAILIYEIILLSEPIKKSE
                     IEWALYCMDIDVPQKIITRLLYLLEKMKLTSSLSYSGTDYFYSRGHRESKLKFGISAS
                     GKIKDSMNIKVAIRQSYLSMDAKDMDETAKKRKNALNQINIVRGGA"
     gene            complement(4102..4374)
                     /locus_tag="IT892_003917"
     CDS             complement(4102..4374)
                     /locus_tag="IT892_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HAP3137068.1"
                     /translation="MALKCPECGTVAHARTAAYEAPSVKRSWYQCQNLECSCTFTALE
                     SVDKIIMKPRRNEQLSDKAQSPEKQQKTLNRYGSASKLSSRQQIPV"
     gene            complement(4380..4931)
                     /locus_tag="IT892_003918"
     CDS             complement(4380..4931)
                     /locus_tag="IT892_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage polarity suppression protein"
                     /protein_id="HAP3137069.1"
                     /translation="MTARGTPDQALTSFRNARILWAGHNESRKAVEQQITSLLAATEK
                     PADYARQLELLRERLDVLKWQINCAARECIYSQHLLMEACTEAALSNFMQANGAALTS
                     ALAPFLKGRGGVDVASRILRSALVRQLAITPPEIAGDYREILDESGLMPDPGMIRDCQ
                     GSYTPAQHLRFQQRLNDINDIQE"
     gene            complement(4928..5671)
                     /locus_tag="IT892_003919"
     CDS             complement(4928..5671)
                     /locus_tag="IT892_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation initiation protein"
                     /protein_id="HAP3137070.1"
                     /translation="MNNTAVNNNLSTFPAVTQRALETMNTARNAWLEARRQQKAAADN
                     IATIRQRRAEMEATTNTLNEEWRTLFRESQGVVSKEMKKLRTEIALGRETLEDFDELL
                     AAQESENALLPQKAAELAGKYIHAHNILVDIRAKQIWEDFMQSHGKALIQTLSLLKST
                     MGREASAVVGVVNSVNDPDTVLKDFIHKHITRPALANDAMPEQDPVFKLAGVAPDYAA
                     RLDFSNQLSPAAMHKIKVRQELAEKEKAV"
     gene            complement(6072..8744)
                     /locus_tag="IT892_003920"
     CDS             complement(6072..8744)
                     /locus_tag="IT892_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000211874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HAP3137071.1"
                     /translation="MTIQTVTQISAAARGKWPVILQMLRIDVPENGRHGPCPKCGGKD
                     RFRLDDLDGRGTWICSQCGNGDGLDLVKLVTGYSVRKAAQEVAQVLNVPDVQELPVKP
                     ARKKAPKRDMGLTVAALMKESHTGESAYLTGKGFAGYPASLTGSVQHISGKDFPAGSL
                     LLPLTTNTGAVTGAQLIAPTGEKSILPGSTMKGAFVSLSPLPSEPPVQVVITEGYATA
                     LTVSQLTAGCVVAAISAGNLPNVAQSLRARWPEVKIIIAGDNDFQDGGENPGRAFAER
                     AAKAVGGWMTLPPGEIKADWNDFHREHGITRAREAFRNGLVLCGEGRTQLPHGFRLTQ
                     EYLWYEKQVQRNGETEIQNVKICSPLRVTAITCDADGGNFGRLLEWEDTWGECRRWAM
                     PMEMLSGSGEELRRVLLVNGLSYISTTGEARARLMEYISLCKPERRVTCVSRTGWHGQ
                     VYVLQDEVSGEGAEGVILQTTSVQGRDFRVSGTTEEWREHVSRYCTGNSRVAFAVSLA
                     FAAPLLRLVGMDGGGYHLKGESTDGKTTTMKAATSVCGGPDYWQTWRATGNALEGCAS
                     RRNDAAMMLDEIREVDGREAGNIAYMLANGQGKGRAGTDGELRTRKHWRLLFFSTGEL
                     SLTEHAAKAGERTFAGMEVRMIQIPSDSGKFGVFEELHGFDSGKALAEHLEWATSCYY
                     GSPFREWLKALTADLNGLTAQAKSLMKEYAAALTPKDAGNQVGRAVNRFALVAMAGEL
                     ATRLGITGWPEGEALRATRVCLNAWLKDRGHTANQEDIAALEQVRSFFTANQYSRFAD
                     WYDERNRPGNMVGWRRVEKGSTAQGTEAVTTFYVMPSGWKEICRGFDPRKVARLCADR
                     GYLLPSTDGKLQTTIRPPEMNPRRLYVFNSEVPG"
     gene            complement(8741..9124)
                     /locus_tag="IT892_003921"
     CDS             complement(8741..9124)
                     /locus_tag="IT892_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5375 domain-containing protein"
                     /protein_id="HAP3137072.1"
                     /translation="MNQPQVSIFPAEMTTALYRRAIASAWRQKMLNETGSDQYGPHSL
                     TVERIEMAIALHIECVLINEYGEAQGAAAALALLTDMLEPSLLTAPPVLTARGCEVMA
                     EMYRTLPAAFDDFCSTGVTLYQGEV"
     gene            complement(9121..9405)
                     /locus_tag="IT892_003922"
     CDS             complement(9121..9405)
                     /locus_tag="IT892_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137073.1"
                     /translation="MNISNGHNGAQGHTLPEKHNTGAFAYGLSEDSFGKLTRARNACD
                     MLQLLFSEYPSQAGALDAGCAHGVAALMEYLLADLTDIAHSCALIEGGAR"
     gene            complement(9437..9796)
                     /locus_tag="IT892_003923"
     CDS             complement(9437..9796)
                     /locus_tag="IT892_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137074.1"
                     /translation="MRNYPHPGERWQHERGWTVTIIRLIEASPSVALVNPEFSCEVLI
                     RHDSDNQLSSCPLAWFEQRYTRLFDVPLLKPAPAPAGGSGSGPLTLHPSVLFIRWRER
                     SIRRSAEPDDGHYSKFL"
     gene            complement(9789..9965)
                     /locus_tag="IT892_003924"
     CDS             complement(9789..9965)
                     /locus_tag="IT892_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006120337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitor Icd-like protein"
                     /protein_id="HAP3137075.1"
                     /translation="MAKQKCTWLFAAINRSQRNARPVMLRITADNERSARRRLAPDYV
                     LSFAGRIPCGGEHA"
     gene            10153..10338
                     /locus_tag="IT892_003925"
     CDS             10153..10338
                     /locus_tag="IT892_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000235891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137076.1"
                     /translation="MATSSTNNKSQQLNARFPHDVVAELESNLEDGETKAQFIVTAVK
                     GEIKRRQRRKNKPEQGS"
     gene            complement(10435..10665)
                     /locus_tag="IT892_003926"
     CDS             complement(10435..10665)
                     /locus_tag="IT892_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001534484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HAP3137077.1"
                     /translation="MEYANSFSDNQTLISAKEVLRRVQRSKAWLYKQLANNTFPRPVK
                     IGTRAISFVESEVDHWIQEQIYASRGERYENH"
BASE COUNT         2817 a         2901 c         2484 g         2939 t
ORIGIN      
        1 atctgccgct ctaccgcatc cctcgaccat aatcccgact caatcaacga actacaagcc
       61 atcgtcctga agccatgccc acaaacctcg accttcgtgt cataccccat tacgcgcaaa
      121 gccttgttca ccgtattctc actcatcggc ttacgtggat cgtgatcgcc cacaaaaatc
      181 agctctcaat ttccgctcat gcttttgatc ttttccaaaa tacttagggc ctgccgcgac
      241 aaaggtacaa ggtgtggtgt ccgcatcttc gagccacgct gagaatgctt gactccttcc
      301 agttgctcac gctcacctgg gattgtccac atagccgttt caaaatctac ttctgaccag
      361 cgggcaaaat gcagctcgct cgaacggatg aaaaccaata aagtgagttc aaccgccagc
      421 cgagttaacg gtctgccaga atagtgatct atgcgatgaa gtaattcagg tatacggttc
      481 agttcaagag ctgcacggtg ctgtcttttc gccgtagcaa ccgcacctgc aatctcttgc
      541 gcggggttgt agtcgattaa gccgctctga acggcaaagc gcataatcgc ggtagtacgc
      601 tgctgtaaac gggcggcaac ttcgagccgc ccggatgact cgactgcttt aatgggtaca
      661 agaagatccc gcgtcttcag ttccgcaatg ttccgcttac cgatagcagt aaagagatta
      721 tcctccagac ttttcaaaac acgagcgcta tgcgatgccg accacttctg attgctggcg
      781 tgccagtctc tggcgactac ttcaacgtta tcgcctcttg ttcctgttct accttaacag
      841 ctttcttgtt ttcactggga tcgacaccat tagctaaaag cttacgagcc tcatcccggc
      901 gtgccctggc atccgccaac gacacttcgg ggtatttccc caatgccagc atcttctctt
      961 taccgccaaa gcgataacgt agccgccagt atttggagcc gttagggtga accagcaaaa
     1021 ccatgccttc accgtcggtc agcttatagg cttttgcttc aggcttagcc gaacgaacct
     1081 tcacatcact cagagccatg atgagtatcc tttcaagggt tctgtgtggg tacaaacatt
     1141 atcgaaccgg gaaatacccg cagttgtacc cgcatcagta agttgatgta gattgaatca
     1201 ggttgactta ggttgagtga aaaagcgagg aaagccttgc ggatactgga ttttaggcac
     1261 aaaaaaagac gtccgttgac gtctattgat gttccgatgg tgcgaaggcc ggaatagaat
     1321 aactatataa ctcattgaac atgatgataa aaattttata gcttatgact tgtgccccat
     1381 tttgtgcccc caacaaaatc ttattgttgc taactagcac aataaatgaa ttagcaagat
     1441 agagttgcct agttaggttc cgtcttacag agcctaacca gaacaaccaa acctctgaac
     1501 caaccttgcg caagctagat aaagtcatgc tgatttatta ggacaacaag ctattaaatt
     1561 tcatattttg aaatttcgct gattacatca tccccatatt tcttaatcat ggaggcaaag
     1621 aatttatgtt caataaattt cgcatagcct aattctcctt taagggttag aatttctttc
     1681 tcagataaaa ccccacacac ataataatgt attttacttc ttaaaagacg ctttctatca
     1741 cgacctaaag acaaataacc atcagtcgta atagttacac cagttacatg tctattaaac
     1801 ttccttgagg taaaaactgt tttctcatgg tttattttaa tattcctaag atttactacg
     1861 ttaagaactt cccttactaa cttaggaaca tcaaataaag ctcctttgac tttggtgcta
     1921 aacgtaagat catcagcata ccttgagtag gtaataccca aatccttgca tcttttcgat
     1981 atttcctcat cgaagaaata cattactgta tttgaaataa tgggagaaga aggtgctcca
     2041 acacttaggc gtaacgggct atttcttctt aacttccaga agaaaagatt tttaagaaca
     2101 aagatatcag tatcagttag ttcaacgcca taatctttta agacagataa aagattatgg
     2161 ggtttgatac tcataaaaaa gtttttaaaa tccattttaa gcaaataatc attattacaa
     2221 tgcattaacg cattagatct aatactttta tcggcttcat aagcgaaagc attttcatga
     2281 actttcaaat tagccaacat atgattgatt actaccttct gtaaggcttt aacttgccta
     2341 gctggttgtg caattaatct atatccatta ccatttcttt tggcgatagg ataaatttta
     2401 tatctgcgtg gaatagtaac aatatacctt ttagcctctt cttcgctaag aaaaagacct
     2461 tttgaaatat aacttagcaa ctccattcta agcccctcca cgcacgatat tgatttgatt
     2521 tagagcattt ttcctttttt ttgcagtctc gtccatatct ttagcatcca tacttaagta
     2581 agattgtcgg attgcaacct taatattcat agaatccttt attttaccac tagcactgat
     2641 accaaattta agtttactct ctctatgccc tcgggaatag aagtagtctg taccactgta
     2701 agataatgat gaggttaatt tcatcttttc aagcaaataa agtaaacgag ttattatttt
     2761 ttgtggcaca tctatatcca tacagtatag tgcccactct atttcgcttt tcttgattgg
     2821 ttctgataaa aggattattt cgtaaatcaa tatagctagg tgcccagtat tttcagggtt
     2881 atatcgctcc gtttttttta cacgttttaa tctagaatga atatcatggt agataagctc
     2941 aacctcatca tatttcatac gatccgattt tggccatgga taaactgata ctgaggcctc
     3001 atctattttt ttaagatact ccaaagggcc taaatatata aaagaagatc tagcaggaat
     3061 attttttcgt tcatttccct caatctcctc aaatggtgcg actacatgca atttttgagc
     3121 tagagacttc ctattaacaa ataatccaag ctcaactaac gaacctgcac tttctaaaca
     3181 gataacaact aatgttgaaa tatttgcaat atcatcttca aagctcatta gatctgaata
     3241 tgccccctct ctgaagtagt catggaagtt ctcagctaaa ataagagaat ctgacaattc
     3301 aggtttgtgg cctgctacat aagtaaatat gtggtctcgt acactcattg gagtggaatt
     3361 tatcggccca ccacaaacaa aaataatagg aggcatgaac tgaacagtga aatttgaata
     3421 tttcaaatct ccaaactgct cttgtaatgc attcatatat gcagaatcac tcacccttgt
     3481 gaccccctac tccaaaagaa aaggtggcta accagccacc ttcgacccct ttacctaaag
     3541 gatgcgcttt agactttcag caagatcctg aatggaacgc agtggcatga aggatcttgc
     3601 tgaaagtgct aaagcgcaac cctaaatgtc cacaataaat tagtgtctgg cgaaacgccc
     3661 gacaaggata aacctgttat cccgcgcgta aaggtagggt taggatagca aaagatgcga
     3721 gattttcaat aagtaagcgt actggctgcc agcaaccacc taaaccattg acatttaaac
     3781 aaaaataaat ctaacaattg aaagcaatac cttattgaat acagcattct tatatctctc
     3841 ttgatatcgc aacatcacaa ttatcaccgt tagtgcgggc agccccgcac gcctgcccgc
     3901 ttcgcttaac agactggttt tcatgcacct cattaatcgt ctcagaagcc agcacacaag
     3961 ggttttctcg tcaaaaatgg tgcataagac tcatgcgttt tcatgcgcca tagacatgca
     4021 ctcatgcgct ctcatgtcag ccaggaaaag ggggtaaaaa atcccggtac tggaccggga
     4081 ttacgtgggc gttctttcta atcagacagg aatctgctga cggcttgaca gttttgacgc
     4141 ggagccatag cgattgagcg ttttctgttg tttttccggg gattgtgctt tgtctgatag
     4201 ctgttcattg cgccggggtt tcatgattat cttatccaca ctctccagtg ccgtaaatgt
     4261 gcaggaacat tccagattct ggcactgata ccacgagcgt ttaactgacg gagcttcata
     4321 ggctgctgtt ctggcgtgtg caactgtacc gcattccgga catttaagtg ccattaatat
     4381 cactcctgta tatcgttaat gtcattcagg cgttgctgaa aacgcagatg ttgtgccggg
     4441 gtgtaagaac cctggcaatc acgaatcatc ccggggtcag gcatcaaacc ggattcatcc
     4501 aggatctcac gataatcccc ggcaatttca ggcggtgtta ttgccagctg gcgaaccaga
     4561 gcactgcgta atatacggga cgcaacgtca acccctccgc gccccttcag gaacggagcc
     4621 agtgcagatg tcagggctgc cccattcgcc tgcataaaat tgctgagagc ggcttctgtg
     4681 caggcctcca tcagtaaatg ctgcgagtaa atgcattcgc gcgcagcaca gttaatttgc
     4741 catttcagca catccagacg ttcccgcagt aattcgagct gtcgggcata atctgctggt
     4801 ttttctgtgg cagcgaggag agatgttatc tgttgttcaa cggcttttcg gctctcatta
     4861 tgtccggccc acagaatacg ggcattccga aaactggtaa gtgcctggtc aggcgtgcct
     4921 cgggccgtca tactgctttc tccttctcag caagttcctg acgaacctta attttatgca
     4981 tagctgccgg agagagttga ttactgaaat ccagacgcgc cgcataatcc ggggcaactc
     5041 ccgccagttt aaacaccggg tcctgctcag gcatcgcatc gttagccaga gccggtctgg
     5101 tgatatgttt atgaataaag tctttcagca ctgtgtccgg gtcattaact gaattcacca
     5161 cacccacaac ggcactggct tcccggccca ttgtggattt aagcaggctc agcgtctgaa
     5221 taagcgcttt tccatgcgac tgcataaaat cctcccagat ttgttttgcg cgaatatcca
     5281 caagaatgtt atgcgcgtgg atatactttc cggctaattc tgcagctttc tgcggcaaaa
     5341 gtgcattttc gctttcctga gccgccagca gctcatcaaa atcctcaagc gtttctcgtc
     5401 ccagcgcaat ttccgtgcgc agttttttca tttcctttga gaccacgccc tgactttcac
     5461 gaaacagcgt gcgccactcc tcattcagtg tgttcgtcgt ggcttccatt tcagcgcgac
     5521 gctggcggat tgtcgcaata ttatccgctg ccgctttctg ctgacgacgt gcttcaagcc
     5581 atgcgtttct ggctgtgttc atggtttcca gtgcccgctg cgttacagcc ggaaaagtgg
     5641 aaaggttgtt attcactgcg gtgttgttca tgacttctcc tgtcgggttg gttcgttacg
     5701 tcaattgtgt cgtggctgac acaagcacac tatcggtgct cagtgtgtgg tggctggcac
     5761 aacggacgct tgcggttatt cagacgtggc tatgaaagcc agccagataa aaatgccctc
     5821 tgtttcagtc tgctttatgt ccctgatgcg gtggaacagg tgaaacatgt gttacagctt
     5881 tgttttataa ggcatttata tacactgcac cggtggaaca tcgcgggtaa caaggtggaa
     5941 cagcggattg gctggcgtta catctgttcc acctcactat ttcagaaggt ggaacaggtt
     6001 cagccctgta aaatacggtt gttccacctg tttcacctgt tacccttaat aaataagact
     6061 cacgcaaagc cttaacccgg cacctcgctg ttgaagacat agagcctgcg gggattcatc
     6121 tctggcgggc gaatggttgt ctggagtttg ccatcagtgg agggcagcag gtatccacga
     6181 tctgcgcaca gacgcgccac cttgcgcggg tcaaatcccc tgcagatttc tttccagccg
     6241 gacggcatga catagaacgt agtgacagct tccgtgccct gcgcggtact gcctttctcc
     6301 accctgcgcc agcccaccat attgccgggg cggttgcgct cgtcatacca gtctgcaaag
     6361 cggctgtact gattcgcggt aaagaaactg cgaacctgct ccagtgcggc gatatcttcc
     6421 tgattggcgg tgtgcccgcg atctttcagc catgcgttca ggcagacgcg ggttgcccgc
     6481 agtgcttcac cctcaggcca gccggtgata cccagacggg ttgccagttc acctgccatc
     6541 gccaccagag caaagcggtt cacagcccgg cccacctgat tgcctgcatc tttcggagtc
     6601 agggcggcag catattcctt catcagcgat tttgcctgtg ccgttagtcc gttaagatca
     6661 gcggtcagtg ctttcagcca ctcccggaac ggcgaaccgt agtagcagga cgtggcccat
     6721 tcaagatgct ctgccagagc cttgccgctg tcgaagccgt gcagctcctc aaaaacgcca
     6781 aacttcccgg aatcgctggg gatctggatc atcctgactt ccatcccggc aaaagtacgc
     6841 tcaccggcct ttgccgcatg ttcggtcaga gacaactcgc cagttgaaaa gaacaacagg
     6901 cgccaatgct tacgggtacg cagctcaccg tccgtaccgg cacggccctt gccctgaccg
     6961 tttgccagca tgtaggcgat attgcctgcc tcgcgtccgt caacttcccg gatctcatca
     7021 agcatcatgg cggcatcgtt gcggcggctg gcgcatccct ccagcgcgtt gccggtggcc
     7081 cgccatgtct gccagtagtc aggcccgccg cagacggagg ttgccgcttt catggtggtg
     7141 gtcttaccgt ctgtcgattc ccctttgagg tggtagccgc cgccgtccat accaaccagc
     7201 cgtaacagtg gtgcagcaaa ggccaggctg acagcaaatg ccacgcggga gttgccggta
     7261 cagtagcggg atacatgctc ccgccattcc tctgttgtgc ccgacacgcg gaaatcacgc
     7321 ccctgcacgg aagtggtctg gagaatgaca ccctctgcac cttcaccgct gacctcatcc
     7381 tgcaggacgt aaacctgacc atgccagcca gtacgactga cgcaggtcac gcggcgttcc
     7441 ggtttacaca gtgagatata ttccatcagg cgtgcgcgtg cctcaccggt ggtgctgata
     7501 taagacagcc cgttaaccag caatacccgg cgcagttcct caccactgcc gctcagcatt
     7561 tccatcggca tcgcccagcg gcgacactca ccccacgtat cttcccattc cagcagtcgt
     7621 ccgaagttac cgccatcggc atcgcaggtg attgccgtca cgcgcagcgg gctgcatatt
     7681 ttgacgttct ggatctccgt ctcaccgttg cgctgtacct gcttttcata ccagagatat
     7741 tcctgggtaa gacggaaccc gtgcggcagt tgcgtgcggc cctccccgca cagcaccaga
     7801 ccgttacgaa aggcttcacg ggcgcgggta ataccgtgct cccgatggaa gtcattccag
     7861 tcggccttaa tctctcccgg tggcagcgtc atccagccgc caacagcttt tgccgcccgt
     7921 tcagcaaagg ctctgccggg attctcaccc ccgtcctgaa aatcgttatc accggcgatg
     7981 ataattttta cctcaggcca gcgtgcccgc agcgactgcg ccacattggg caggttgccc
     8041 gcagatatgg cagccactac gcatccggca gtgagctgac ttaccgtcag cgccgtagcg
     8101 taaccttcgg taatcaccac ctgtaccggt ggttcagacg gtaacgggct gagcgacaca
     8161 aacgcgcctt tcatcgtgct gccgggcagt atgctttttt cacccgtcgg ggcgataagc
     8221 tgtgcaccag tcacggctcc ggtgttggtc gtgagtggta acagcaggga accggcagga
     8281 aaatccttac cgctgatatg ctgcacgctt ccggtcagag aggccgggta tccggcgaac
     8341 ccttttcctg tcagataggc gctttctccc gtgtggctct ctttcatcag cgccgccacg
     8401 gtaagaccca tgtcgcgttt aggggctttt tttctggcag gcttaacagg cagttcctgc
     8461 acatccggca cattaagcac ctgcgccacc tcctgcgcag cctttctgac gctgtaaccg
     8521 gttacgagct taaccagatc cagaccgtca ccattgccac actggctgca gatccacgtc
     8581 ccgcgcccgt caaggtcatc aaggcgaaaa cgatccttgc ccccacattt cgggcaggga
     8641 ccgtgcctgc cgttttcagg tacatcaata cgcagcatct ggagaataac gggccatttc
     8701 ccccgtgcgg cggctgaaat ctgcgtaacc gtctgtattg tcatacttcc ccctgataca
     8761 acgtcacacc ggtactgcag aagtcatcaa aggccgccgg aagcgtgcgg tacatctccg
     8821 ccatcacttc acagccgcgc gcggtcagta ccggcggcgc ggtcagcagt gacggctcca
     8881 gcatgtcagt cagcagtgcc agcgcggcag cggcgccctg tgcttcgccg tactcgttaa
     8941 tcagtacgca ctcgatatgc agcgcaatgg ccatttcaat acgctccacc gtcaggctgt
     9001 gcggaccata ctgatcactg ccagtttcgt tcagcatttt ctgccgccat gctgaagcaa
     9061 tagcccgccg gtaaagcgcg gtggtcattt ctgccgggaa aatggaaacc tgcggctggt
     9121 tcatctggca cctccttcaa tcagtgcgca gctgtgtgca atatccgtca aatctgccag
     9181 caggtactcc atcagcgcgg cgacaccatg cgcacagcca gcgtccagtg ctccggcctg
     9241 agacgggtat tcagaaaaga gaagctggag catgtcgcag gcatttcttg cgcgggtcag
     9301 ttttccgaaa ctgtcctctg acaacccata ggcaaaagca ccggtattgt gtttttcagg
     9361 caaagtgtgg ccctgagcac cgttgtgccc gtttgaaata ttcatcgtgg attactccgt
     9421 tttcagcggt attttgtcag agaaactttg aatagtgacc gtcgtcaggc tcagcagaac
     9481 gccgtatgct acgctcccgc cagcggataa atagcacaga cggatgcagt gtcagcgggc
     9541 cggaaccact accgccagca ggagctggtg caggcttcaa gagcggtaca tcaaacaggc
     9601 gcgtataccg ctgttcaaac catgccagag ggcaggaaga aagctggttg tcgctgtcat
     9661 gacgtatcag cacttcacag ctgaattcag gattaaccag cgccacagag ggcgaggctt
     9721 ctattaatcg gataatcgtg accgtccagc cacgttcatg ctgccagcgt tcgccggggt
     9781 gcggataatt acgcatgttc acctccgcag ggaatgcgcc cggcaaagct cagtacatag
     9841 tccggggcaa gtctgcgccg cgctgaccgc tcgttatctg cggtgatcct taacatcaca
     9901 ggacgggcat tgcgttgact gcggttgatc gccgcaaata accaggtaca cttctgttta
     9961 gccatcttcg ttacctcatt tagcggattg gtcagaagcc cggttagtgt tgctgcactg
    10021 tcgggcttcg cactcacaag gtgaatcgca cctttaattt taaagctacc cttaagtgaa
    10081 tcgcacttca agctttttat tatcattttt tttgcatata ctgaatcgca cctaacgcga
    10141 ggagatccag taatggcaac gagttcaact aacaacaagt cgcagcaact taatgctcgt
    10201 ttcccacatg atgtagttgc agaattagaa agcaaccttg aagatggaga aacgaaagcg
    10261 caattcattg ttacggctgt aaaaggcgag attaaacgcc gacagcgcag gaaaaataag
    10321 ccagagcaag gtagttgaat agagaagcca acagacgttc tctctgtttc catgttaatt
    10381 tcagtaagcg acaatatttt taagcccaca aattcattat gtcgggcttt tttattagtg
    10441 attttcatat cgctcaccac gagaggcata tatttgctct tgaatccagt gatccacttc
    10501 gctttcaaca aatgaaattg cacgagttcc tattttcacc ggacggggaa atgtattgtt
    10561 tgcaagctgt ttgtaaagcc atgccttgct acgctgaacg cgtcttaaga cctcttttgc
    10621 tgagataaga gtctgattat ctgaaaagct gtttgcatat tccatcttgt tactccgtgt
    10681 tctacttaag ttcacggtga ctttaaacac tgggaaaaag tgattctagt gataatggaa
    10741 tctattaaga caaatattga ttctattgaa aaacaataat ctccactgaa aaaagaagta
    10801 atattcatat gaaagaacac ggagagaagg aaatgcacaa aaaaaaacaa aatcaataga
    10861 attcatatgg ataggatgga aaatcaaaaa atcatatgtc aaaaggtatt attgcatttt
    10921 aacgattcat attacctagg aattagcaca gtattacacc atattacatc gtattacccc
    10981 ctatagcccg ttagagcctc ttgtggccct tctattgaga gatagccaga aaattaataa
    11041 atttactctc cgtattttat aatgtctttc ccaagcttta ttttcttata aaacgtagct
    11101 tttttaaccc ctttcattag aatctcattc tcattacaaa a
//
LOCUS       DACAOP010000125        10757 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.125, whole genome shotgun sequence.
ACCESSION   DACAOP010000125 DACAOP010000000
VERSION     DACAOP010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10757
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.125"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(77..1123)
                     /gene="aroH"
                     /locus_tag="IT892_003927"
     CDS             complement(77..1123)
                     /gene="aroH"
                     /locus_tag="IT892_003927"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroH"
                     /protein_id="HAP3137078.1"
                     /translation="MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEK
                     ILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVG
                     WKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
                     IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMT
                     IYQTSGNPYGHIIMRGGKKPNYHADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRR
                     QLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGSQPLTYGQSITDPCLGWEDTE
                     RLVEKLASAVDTRF"
     gene            complement(1280..2113)
                     /gene="ppsR"
                     /locus_tag="IT892_003928"
     CDS             complement(1280..2113)
                     /gene="ppsR"
                     /locus_tag="IT892_003928"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="posphoenolpyruvate synthetase regulatory
                     kinase/phosphorylase PpsR"
                     /protein_id="HAP3137079.1"
                     /translation="MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVE
                     NESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQ
                     EMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSR
                     CGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIR
                     EERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRM
                     Y"
     gene            2446..4824
                     /gene="ppsA"
                     /locus_tag="IT892_003929"
     CDS             2446..4824
                     /gene="ppsA"
                     /locus_tag="IT892_003929"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HAP3137080.1"
                     /translation="MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVS
                     VPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQP
                     ELENAIREAYAQLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
                     KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQV
                     VFITSAWGLGEMVVQGAVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHG
                     KQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQ
                     ARPETVRSRGQVMERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVL
                     VTDMTDPDWEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGENV
                     TVSCAEGDTGYVYAELLEFSVKSSSVETMPDLPLKVMMNVGNPDRAFDFACLPNEGVG
                     LARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLTEGIATL
                     GAAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFAL
                     ECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIP
                     SNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRA
                     AKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK"
     gene            complement(4881..6581)
                     /gene="fadK"
                     /locus_tag="IT892_003930"
     CDS             complement(4881..6581)
                     /gene="fadK"
                     /locus_tag="IT892_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416216.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="medium-chain fatty-acid--CoA ligase"
                     /protein_id="HAP3137081.1"
                     /translation="MHPTGPHLGPDVLFRESNMKVTLTFNEQRRAAYRQQGLWGDASL
                     ADYWQQTARAMPDKIAVVDNHGASYTYSALDHAASCLANWMLAKGIESGDRIAFQLPG
                     WCEFTVIYLACLKIGAVSVPLLPSWREAELVWVLNKCQAKMFFAPTLFKQTRPVDLIL
                     PLQNQLPQLQQIVGVDKLAPATSSLSLSQIIADNTSLTTAITTHGDELAAVLFTSGTE
                     GLPKGVMLTHNNILASERAYCARLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARS
                     VLLDIFTPDACLALLEQQRCTCMLGATPFVYDLLNVLEKQPADLSALRFFLCGGTTIP
                     KKVARECQQRGIKLLSVYGSTESSPHAVVNLDDPLSRFMHTDGYAAAGVEIKVVDDAR
                     KTLPPGCEGEEASRGPNVFMGYFDEPELTARALDEEGWYYSGDLCRMDEAGYIKITGR
                     KKDIIVRGGENISSREVEDILLQHPKIHDACVVAMSDERLGERSCAYVVLKAPHHSLS
                     LEEVVAFFSRKRVAKYKYPEHIVVIEKLPRTTSGKIQKFLLRKDIMRRLTQDVCEEIE
                     "
     gene            complement(6584..6877)
                     /locus_tag="IT892_003931"
     CDS             complement(6584..6877)
                     /locus_tag="IT892_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HAP3137082.1"
                     /translation="MSQNATVNVDIKLGVNKFHVDEGHPHIILAENPDINEFHKLMKA
                     CPAGLYKQDDAGNIHFDSAGCLECGTCRVLCGNTILEQWQYPAGTFGIDFRYG"
     gene            complement(6874..8163)
                     /locus_tag="IT892_003932"
     CDS             complement(6874..8163)
                     /locus_tag="IT892_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP3137083.1"
                     /translation="MSDDKFDAIVVGAGVAGSVAALVMARAGLDVLVIERGDSAGCKN
                     MTGGRLYAHTLEAIIPGFAVSAPVERKVTREKISFLTEESAVTLDFHREQPDVPQHAS
                     YTVLRNRLDPWLMEQAEQAGAQFIPGVRVDALVREGNKVTGVQAGDDILEANVVILAD
                     GVNSMLGRSLGMVPASDPHHYAVGVKEVIGLTPEQINDRFNITGEEGAAWLFAGSPSD
                     GLMGGGFLYTNKDSISLGLVCGLGDIAHAQKSVPQMLEDFKQHPAIRPLISGGKLLEY
                     SAHMVPEGGLAMVPQLVNEGVMIVGDAAGFCLNLGFTVRGMDLAIASAQAAATTVIAA
                     KERADFSASSLAQYKRELEQSCVMRDMQHFRKIPALMENPRLFSQYPRMVADIMNEMF
                     TIDGKPNQPVRKMIMGHAKKIGLINLLKDGIKGATAL"
     gene            complement(8219..9157)
                     /locus_tag="IT892_003933"
     CDS             complement(8219..9157)
                     /locus_tag="IT892_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HAP3137084.1"
                     /translation="MSQLNSVWVFSDNPERYAELFGGAQQWGQQVYAIVQNTDQAQAV
                     MPYGPKCLYVLAQNDALQRTENYAESIAALLKDKHPAMLLLAATKRGKALAARLSVQL
                     NAALVNDATAVDIVDGHICAEHRMYGGLAFAQEKINSPLAIITLAPGVQEPCTSDTSH
                     QCPTETVPYVAPRHEILCRERRAKAASSVDLSKAKRVVGVGRGLAAQDDLKMVHELAA
                     VLNAEVGCSRPIAEGENWMERERYIGVSGVLLKSDLYLTLGISGQIQHMVGGNGAKVI
                     VAINKDKNAPIFNYADYGLVGDIYKVVPALISQLSR"
     gene            complement(9177..9941)
                     /locus_tag="IT892_003934"
     CDS             complement(9177..9941)
                     /locus_tag="IT892_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein"
                     /protein_id="HAP3137085.1"
                     /translation="MKIITCFKLVPEEQDIVVTPEYTLNFDNADAKISQFDLNAIEAA
                     SQLATDDDEIAALTVGGSLLQNSKVRKDVLSRGPHSLYLVQDAQLEHALPLDTAKALA
                     AAIEKIGFDLLIFGEGSGDLYAQQVGLLVGEILQLPVINAVSAIQRQGNTLVIERTLE
                     DDVEVIELSVPAVLCVTSDINVPRIPSMKAILGAGKKPVNQWQASDIDWSQSAPLAEL
                     VGIRVPPQTERKHIIIDNDSPEAIAELAEHLKKALN"
     gene            10257..>10757
                     /locus_tag="IT892_003935"
     CDS             10257..>10757
                     /locus_tag="IT892_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAP3137086.1"
                     /translation="MYQRCFDNASETLFVAGKTPRLSRFAFSDDPKWESGHHVHDNET
                     ELIYVKKGVARFTIDSSLYVAHADDIVVIERGRLHAVASDVNDPATTCTCALYGFQFQ
                     GAEENQLLQPHSCPVIAAGQGKEVIKTLFNELSVILPQSKNSQTSSLWDAFAYTLAIL
                     YYENFKN"
BASE COUNT         2588 a         2741 c         2786 g         2642 t
ORIGIN      
        1 ccagagcaag cagtaatttg ttgagaagac aacaagttgc gcagaaatgc ccattccgtc
       61 aggaatgggc acgcattcag aagcgggtat ctaccgcaga ggcgagtttt tcgaccaggc
      121 gttcggtatc ctcccagccc agacacgggt cggtaatgga ttgaccgtaa gtgagcggct
      181 gactgccgac gattttttgc gttccttcgc gcaggaaact ttccgccata attccagcaa
      241 tcgccgtaga gccattgcgg atttgctgac aaatatcctc acaaacttct aactggcgac
      301 ggtgctgctt ctggcagtta ccgtggctga aatccaccac cagatgttca ggtaaatcaa
      361 actcgtgcag cgtatcgcag gctgcggcga tatcatcggc atgataattc ggctttttgc
      421 cgccacgcat aataatgtgg ccatacgggt tgccgctggt ctgatagatg gtcatctgac
      481 catttttgtc tggcgagagg aacatatggc tggcgcgggc tgcgcggata gcatccacag
      541 caatccgcgt attgccatcg gtaccatttt taaaacctac cggacaggag agtgccgaag
      601 ccatttcgcg gtggatctga ctttcggtag tacgtgcgcc aatcgcgccc caactgatta
      661 aatcagcaat aaactgaccg gtcaccatat cgaggaactc ggtcgcggtt gggacgccca
      721 gctcatttac ctgtaaaagt aatttgcgcg ccagctccag accgtgattt acccgatagc
      781 tgccgtttaa atctggatcg gagattagtc ctttccagcc gacaacagtt cgtggttttt
      841 caaaataggt gcgcattacg atttccagcc gtgactggta ctggttgcgc agcgactgca
      901 gacgggtggc gtactccatt gcagcggtga gatcgtggat cgagcagggg ccaataatga
      961 ccaacagtcg cttatcttca ccattcagta ttttttcaat tctgcggcgg gagtcggtga
     1021 catgggtggc gacgccaggc gttacgggat accgtagcgc gagttcggcg ggcgttacca
     1081 ggctctcaat acgcgcagta cggagttcgt cagttctgtt cattacaagt ctcagaaatt
     1141 tgttgcttct acggcaggac tgccgggaag tgatgcgcat cacgataaac caatcgctgc
     1201 tgatttcaag tgcgaggtgt gtcacacctc gccgggtggt tagcatgata acaaaaaaat
     1261 aagctaatgc actagttctc tagtacattc ggcgactaag gcccatgata tcgaggatct
     1321 tggtggcaat ctcttctacc gaataattgg tactgttaat ccacgggatc tgatttttac
     1381 ggtacaaggc ttccacttcc gcgacttcca tcctgcactg acgaagcgag gcatagcgac
     1441 tgttctcccg acgttcctcg cgaatcgccg ccagacgttc cgggtcgata gtcaggccga
     1501 acaatttatg ctgaagcggt ttgagcgacg cgggtagcac cagattatcc atatcgtcgg
     1561 caataaaggg gtagtttgcc gcgcggatac caaactgcat tgccagatac agactggtgg
     1621 gggttttacc acagcgagaa acaccgagca ggatcacctg agcctggtcc agattgcgca
     1681 acgaaatgcc gtcatcgtgg gcgagggtgt aatcaatcgc cgcaatgcgc gcatcatatt
     1741 tattgagatt attagggtta aggccatggg tacgatgagc aatcggcgtt ggatccagtt
     1801 tcatctcttg ttgtagcggg gcaaccagcg cctgaacgat atcctggcaa aagccttcac
     1861 tttgcaagat gatggcgcga atctccggca acacgatgga gtagaagacc agcgggcgca
     1921 cgcctgtctg gtgataaatt gcgtcaatct gatccttcac tgcccgtgca cggctctcat
     1981 tttcgacaaa cggcagcgtg atgctgctga tagtgacggg aaattgtgac attactgcgt
     2041 gtcctaatac ctccgcagtt attgccgtac catcagaaat ataaaaaacg tggcgatcaa
     2101 cagcattatc cattttgttc ttcccgtgat gcagacataa ttctatgaaa gcataaatta
     2161 aaaacgcaca gaagcgtaga acgttatgtc tggtttataa aatgaacctt caattttatt
     2221 ttttatgaaa acagcatttc atttttatgg tttcgtttat accgatggtt tatgtggaaa
     2281 ttgtcgaaga gagcagattt gcgcaacgct gggatcagtc ttaaaaagta aaaaaatata
     2341 tttgcttgaa cgattcaccg tttttttcat ccggttaaat atgcaaagat aaatgcgcag
     2401 aaatgtgttt ctcaaaccgt tcatttatca caaaaggatt gttcgatgtc caacaatggc
     2461 tcgtcaccgc tggtgctttg gtataaccaa ctcggcatga atgatgtaga cagggttggg
     2521 ggcaaaaatg cctccctggg tgaaatgatt actaatcttt ccggaatggg tgtttccgtt
     2581 ccgaatggtt tcgccacaac cgccgacgcg tttaaccagt ttctggacca aagcggcgta
     2641 aaccagcgca tttatgaact gctggataaa acggatattg acgatgttac tcagcttgcg
     2701 aaagcgggcg cgcaaatccg ccagtggatt atcgacactc ccttccagcc tgagctggaa
     2761 aacgccatcc gcgaagccta tgcacagctt tccgccgatg acgaaaacgc ctcttttgcg
     2821 gtgcgctcct ccgccaccgc agaagatatg ccggacgctt cttttgccgg tcagcaggaa
     2881 accttcctca acgttcaggg ttttgacgcc gttctcgtgg cagtgaaaca tgtatttgct
     2941 tctctgttta acgatcgcgc catctcttat cgtgtgcacc agggttacga tcaccgtggt
     3001 gtggcgctct ccgccggtgt tcaacggatg gtgcgctctg acctcgcatc atctggcgtg
     3061 atgttctcca ttgataccga atccggcttt gaccaggtgg tgtttatcac ttccgcatgg
     3121 ggccttggtg agatggtcgt gcagggtgcg gttaacccgg atgagtttta cgtgcataaa
     3181 ccgacactgg cggcgaatcg cccggctatc gtgcgccgca ccatggggtc gaaaaaaatc
     3241 cgcatggttt acgcgccgac ccaggagcac ggcaagcagg ttaaaatcga agacgtaccg
     3301 caggaacagc gtgacatctt ctcgctgacc aacgaagaag tgcaggaact ggcaaaacag
     3361 gccgtacaaa ttgagaaaca ctacggtcgc ccgatggata ttgagtgggc gaaagatggc
     3421 cacaccggta aactgttcat tgtgcaggcg cgtccggaaa ccgtgcgctc acgcggtcag
     3481 gtcatggagc gttatacgct gcattcacag ggtaagatta tcgccgaagg ccgtgctatc
     3541 ggtcatcgca tcggtgcggg tccggtgaaa gtcatccatg acatcagcga aatgaaccgc
     3601 atcgaacctg gcgacgtgct ggttactgac atgaccgacc cggactggga accgatcatg
     3661 aagaaagcat ctgccatcgt caccaaccgt ggcggtcgta cctgtcacgc ggcgatcatc
     3721 gctcgtgaac tgggcattcc ggcggtagtg ggctgtggag atgcaacaga acggatgaaa
     3781 gacggtgaga acgtcactgt ttcttgtgcc gaaggtgata ccggttacgt ctatgcggag
     3841 ttgctggaat ttagcgtgaa aagctccagc gtagaaacga tgccggatct gccgttgaaa
     3901 gtgatgatga acgtcggtaa cccggaccgt gctttcgact tcgcctgcct accgaacgaa
     3961 ggcgtgggcc ttgcgcgtct ggaatttatc atcaaccgta tgattggcgt ccacccacgc
     4021 gcactgcttg agtttgacga tcaggaaccg cagttgcaaa acgaaatccg cgagatgatg
     4081 aaaggttttg attctccgcg tgaattttac gttggtcgtc tgactgaagg gatcgcgacg
     4141 ctgggtgccg cgttttatcc gaagcgcgtc attgtccgtc tctctgattt taaatcgaac
     4201 gaatatgcca acctggtcgg tggtgagcgt tacgagccag atgaagagaa cccgatgctc
     4261 ggcttccgtg gcgcgggccg ctatgtttct gacagcttcc gcgactgttt cgcgctggag
     4321 tgtgaagcag tgaaacgtgt gcgcaacgac atgggactga ccaacgttga gatcatgatc
     4381 ccgttcgtgc gtaccgtaga tcaggcgaaa gcggtggttg aagaactggc gcgtcagggg
     4441 ctgaaacgtg gcgagaacgg gctgaaaatc atcatgatgt gtgaaatccc gtccaacgcc
     4501 ttgctggccg agcagttcct cgaatatttc gacggcttct caattggctc aaacgatatg
     4561 acgcagctgg cgctcggtct ggaccgtgac tccggcgtgg tgtctgaatt gttcgatgag
     4621 cgcaacgatg cggtgaaagc actgctgtcg atggctatcc gtgccgcgaa gaaacagggc
     4681 aaatatgtcg ggatttgcgg tcagggtccg tccgaccacg aagactttgc cgcatggttg
     4741 atggaagagg ggatcgatag cctgtctctg aacccggaca ccgtggtgca aacctggtta
     4801 agcctggctg aactgaagaa ataaaataaa tccccggcgg cgtttagtcg ccggggttat
     4861 gtgatccccg aagatgaaac ttattcaatc tcttcacaga catcctgcgt taaacgccgc
     4921 ataatatctt ttcttaacaa aaacttttgt attttacctg aggtagttcg cggtagtttt
     4981 tcgattacca cgatatgttc aggatattta tattttgcga cccgtttacg gctaaaaaaa
     5041 gccactacct cttccagcga taatgaatga tgcggcgctt tcagcacgac ataagcgcat
     5101 gatcgttcac ctaaacgttc atcggacatt gcaaccacac aggcatcgtg aattttagga
     5161 tgctgcaata aaatatcttc cacttcacgg ctgctaatat tttcgccgcc gcggacaata
     5221 atatcttttt tgcgtccggt aatttttata tagccagcct catccatacg gcagagatcg
     5281 ccgctgtaat accagccttc ttcatccagg gcacgggcgg ttaattcagg ttcatcaaaa
     5341 taccccataa acacattggg gccacgcgag gcttcttcac cttcgcaacc tggcggtaag
     5401 gtcttgcgtg cgtcatcgac cactttaatc tctacacctg cggcagcgta accatcggtg
     5461 tgcataaagc gcgacaaagg atcatcgaga ttcaccaccg catgcggcga actttctgtg
     5521 gaaccataaa cacttaataa tttaatgccg cgctgctggc attcacgcgc cacttttttg
     5581 gggattgtgg ttccgccgca aagaaagaaa cgcagcgctg aaaggtccgc gggttgtttc
     5641 tctagtacat tcaaaagatc atagacaaac ggcgttgcgc cgagcataca ggtgcaacgc
     5701 tgctgctcaa gcagcgcgag acacgcatca ggagtgaaaa tatctaacaa cacgctgcga
     5761 gcgccaatta agaatggtgc cgttacgcca tgcagaaagc ccgttgcgtg accaagtggc
     5821 gcaggcatca taaagacatc ctgccaggtc agattcagtc gcgcgcaata agcccgctca
     5881 ctggcgagaa tattgttatg cgttagcatc acgccctttg gcagaccctc ggttccggag
     5941 gtaaacagca ccgcagctaa ttcatcgccg tgggtcgtta tcgccgtggt cagtgaggta
     6001 ttgtcggcga taatctgact taatgagagg gaagaggtgg cgggagccag tttgtccacg
     6061 ccgacaattt gttgtagttg tggaagctga ttttgcagcg gcaggattaa atctaccgga
     6121 cgcgtttgtt taaacaacgt cggtgcaaag aacatttttg cctgacactt attgagcacc
     6181 cacaccagtt ctgcttcccg ccaggaaggc aacagcggca cggaaactgc accgattttc
     6241 aggcaggcaa gatagataac ggtaaattca caccagccag gcagttgaaa tgcgatgcga
     6301 tcgcctgatt caataccctt cgctaacatc cagtttgcca gacagctcgc ggcgtgatcg
     6361 agcgcgctat aggtgtacga tgcaccatga ttatcgacca cggcaatttt gtctggcatc
     6421 gcacgagcgg tctgctgcca gtaatcggcc agcgaagcat cgccccataa cccttgctga
     6481 cgatacgccg cacgacgttg ttcgttaaac gttaatgtca ctttcatgtt ggactctcga
     6541 aacagaacat caggcccgag atgcgggcct gtgggatgca tgattagccg tagcgaaaat
     6601 caataccgaa ggtgcctgcg ggatattgcc actgttcgag aatagtgtta ccgcacagca
     6661 cccgacaggt gccgcactcc agacaaccgg cggaatcaaa atgaatgttt cctgcgtcat
     6721 cctgcttata aagtccggca gggcaggctt tcattaattt atggaattca ttgatatcgg
     6781 gattttccgc cagaatgata tgcgggtggc cctcatcaac atggaattta ttgacgccta
     6841 atttgatgtc gacgttaacc gtagcgttct ggctcatagc gcggttgctc ccttaatgcc
     6901 atctttcagc aagttgatca gcccaatttt cttcgcatgt cccatgatca tttttcgtac
     6961 cggctggttt ggtttgccgt cgatggtgaa catctcgttc atgatgtcgg ctaccattcg
     7021 tgggtattgg ctaaacaggc gcgggttttc catcagcgcc gggatcttgc gaaaatgctg
     7081 catatcacgc atgacgcagc tttgttccag ctcacgtttg tattgcgcca gactgctggc
     7141 ggagaaatcc gcgcgttctt tggcggcgat caccgttgtg gcggcagcct gagccgatgc
     7201 aatggctaaa tccatgccgc ggaccgtaaa acccaaattc aggcagaagc ctgcggcgtc
     7261 accaacgatc atcacgccct cgttaaccag ttgcggcacc attgccagac cgccttccgg
     7321 caccatatgc gcggaatatt caagcagttt gccgccgcta atcagcgggc gaatggcggg
     7381 gtgttgttta aaatcttcca gcatttgcgg cacgcttttt tgcgcatggg cgatatcacc
     7441 caatccacaa accagcccca aggatatgga atccttgttg gtatagagaa atcccccgcc
     7501 catcaggccg tcagaagggg aaccggcaaa cagccaggcg gcaccttcct cgcccgtaat
     7561 attaaagcga tcgttgatct gttctggtgt gaggccaata acctctttaa caccaacagc
     7621 gtaatgatgc ggatcggaag cgggaaccat tcccagcgag cggccaagca tcgagttaac
     7681 gccatcagcc agaatcacca cattcgcttc gagaatatca tccccagcct gcacgccagt
     7741 gaccttgttt ccttcacgaa ccagcgcgtc gacgcgaacg cctgggataa actgcgcgcc
     7801 cgcctgctcg gcttgttcca tcaaccacgg gtccagacga ttacgcaata cggtataaga
     7861 tgcgtgttgc ggaacatctg gctgctcgcg gtgaaaatcg agggtaacgg cgctttcttc
     7921 ggttaagaag gagattttct cgcgtgtgac cttgcgttct accggcgctg atactgcaaa
     7981 gcctggaatg attgcttcaa gtgtgtgggc ataaagacgc ccgccggtca tgtttttaca
     8041 tccggcactg tcgccgcgtt ctatcaccag gacatccagc ccggctcgtg ccatgaccag
     8101 tgcggcaacg ctaccagcaa cgcccgcacc gaccacaatg gcatcaaatt tgtcatccga
     8161 catgcgttat gctcccttcc cgctgcgttt acagcgggag atgtggttga aaggggaatt
     8221 agcggctcaa ctggctaatc agggcaggga cgactttgta gatatcgccc accagaccgt
     8281 agtcggcata gttgaagatt ggcgcatttt tatctttatt gatggcgaca atcacttttg
     8341 cgccgttgcc gccaaccata tgctggatct gcccggagat ccccagcgtc aggtagagat
     8401 cggatttcag caacacgccg gagacaccga tataacgttc acgctccatc cagttctcgc
     8461 cttcggcaat tggacgtgaa cagccgactt cagcattcag caccgccgcc agttcgtgga
     8521 ccatttttag gtcatcctgc gccgccagtc cacgaccgac gccaaccaca cgttttgctt
     8581 tgctcaggtc cacgctgctt gcggctttcg cacggcgttc gcgacagaga atttcatgac
     8641 gcggagcaac ataaggtacc gtttctgtcg ggcactgatg agaggtatca ctggtgcacg
     8701 gttcctgaac accgggtgca agggtaatga tcgccagcgg gctgttgatc ttttcctgag
     8761 cgaacgctaa cccgccatac atccggtgtt cggcgcaaat gtgaccatcg acaatatcca
     8821 ccgccgtggc atcgttcacc agcgccgcat tcagttgcac acttaaccgt gctgccagcg
     8881 ctttaccacg tttcgtcgcg gccaacagca acatagcggg gtgtttatct ttcagcaggg
     8941 cagcaatgct ttcggcgtaa ttttcagtgc gttgcagcgc gtcgttttgc gcaagaacat
     9001 aaagacattt tggaccataa ggcataactg cctgcgcctg gtcggtattt tgtacaatgg
     9061 catacacctg ttggccccat tgctgagcgc cgccaaacag ttcagcataa cgttcaggat
     9121 tatcgctaaa gacccagacg ctgtttaatt gactcatcgt ttcttctccg taggcttcag
     9181 ttcagggctt tcttcagatg ttccgccagc tcggcaatgg cctccggcga atcgttatcg
     9241 ataatgatgt gcttacgttc tgtttgcggc ggtacgcgaa tgccgaccag ttcagcaagt
     9301 ggcgcgctct ggctccagtc aatatcactt gcctgccact gatttaccgg ttttttaccc
     9361 gcgccgagaa tggctttcat cgaaggaatg cgtggcacgt taatatcgga ggtgacgcag
     9421 agcacggctg gaacagagag ttcaataact tcaacatcat cttcaagcgt gcgttcaatc
     9481 accagtgtat tgccctgacg ctgaatagca ctcactgcat taatcaccgg aagttgcaga
     9541 atttctccga ccagcaagcc aacctgctgg gcataaaggt cgccggaacc ttcaccaaag
     9601 atcagtaaat cgaagccgat cttttcaatt gctgccgcca gcgcttttgc ggtatcgaga
     9661 ggcagtgcat gttcaagttg cgcatcctgc accaaataca ggctgtgcgg cccgcgggat
     9721 agcacgtctt tgcgcacttt cgagttctgc aacaatgagc cgccaacggt cagcgcggct
     9781 atctcatcgt catctgttgc gagctggctt gcagcttcaa tggcattgag atcgaactgg
     9841 ctgattttgg cgtcggcatt gtcgaaattc agggtgtatt ctggagtgac aacaatgtcc
     9901 tgttcttcag gcaccagctt aaagcaggtt attattttca tgatttctcc tgtgagtcgc
     9961 atacggaacc atctccgatg gaaggtaaaa atggcctgaa aatagtgtgc gatagcggtg
    10021 cggggttttc gacggagcaa gctgttttcc ttgccaacaa tcttgcaaaa aaaatgcgat
    10081 cgctaaaaca aaagtgcaat ttgcggcaat atagttattc catgaccgta caatcttgca
    10141 ttcagtgtaa ataatcttgt ttagctctcg ctaaacgcgg ttgtataacc gcaatacacg
    10201 ccgtatttta tccggcatat attgtttttg cttgctcatg gaatagggag gttgtcatgt
    10261 atcaacgctg ttttgataac gccagtgaaa cgctgtttgt cgccggtaaa acgccacggc
    10321 tttcacgttt tgcatttagc gatgatccaa aatgggagtc cggacatcac gttcatgaca
    10381 atgaaaccga gttgatttac gtcaagaaag gggttgcaag gtttaccatc gattcttcgt
    10441 tatatgtcgc acatgcggat gacattgtgg tgatagaacg cggcaggctg catgcggtgg
    10501 cctctgacgt taacgatccg gcaacgacgt gtacctgtgc gctgtacggc tttcagtttc
    10561 agggggctga ggaaaatcag ctactgcaac cgcattcttg tccggtaatt gccgcggggc
    10621 agggaaaaga agtcataaaa accttattta atgagctaag tgtgattttg ccgcaaagta
    10681 aaaatagcca aacatcttcg ttatgggatg catttgccta tacgttagcc attctttact
    10741 acgaaaattt taaaaat
//
LOCUS       DACAOP010000126        10576 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.126, whole genome shotgun sequence.
ACCESSION   DACAOP010000126 DACAOP010000000
VERSION     DACAOP010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10576
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.126"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..670
                     /locus_tag="IT892_003936"
     CDS             <1..670
                     /locus_tag="IT892_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HAP3137087.1"
                     /translation="NKIMFLGSSCIYPKFAKQPISESELLQGTLESTNEPYAIAKIAG
                     IKLCESYNRQHNRDYRSVMPTNLYGENDNFHPSNSHVIPALLRRFHEAKLEGLPQVVV
                     WGSGTPMREFLHVDDMAAASIYVMELDKALWQEQTQPMLSHINVGTGVDCSIKELAET
                     ISKVVGYQGGVVFDSTKPDGTPRKLLDVSRLEGLGWKHQINLEAGLARTYEWFLKNQK
                     SFRS"
     gene            672..1139
                     /locus_tag="IT892_003937"
     CDS             672..1139
                     /locus_tag="IT892_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosyl hydrolase"
                     /protein_id="HAP3137088.1"
                     /translation="MFLDDNAFKNIIRNTPLISIDLIIQNEKDEYLVGKRNNRPARGF
                     WFVPGGRILKDESLDNGFARLTQNEIGIKMIRNESTFLGIFQHFYDDNFFNNEFSTHY
                     IVLAYKTSIISSGLVFPHEQHNEYHWMGVDEILNNDLVHFNTKAYFMNVALDF"
     gene            1142..2356
                     /locus_tag="IT892_003938"
     CDS             1142..2356
                     /locus_tag="IT892_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014070931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WcaI family glycosyltransferase"
                     /protein_id="HAP3137089.1"
                     /translation="MKLLVYGINYRPELTGIGKYSGEMVKWFVDNDLDVRVITAPPYY
                     PAWKIANNYSGWKYTKEKHPEIVYRCPLYVPNKPSTIKRLLHLSSFAFSSFFPLLMQA
                     RWKPDYIICIVPTLFCVPGALLLRKLTRAKVIIHIQDFEVDAMLGLGMAKKGVFATFA
                     KKFEKWCLTSADKVSTISKTMLSNASGKGVPQSNLIFFPNWSELERFKNVDGVKSVQL
                     KEEFGIAEDKKVILYSGNIGEKQGLEIVISAAQKMASNNFVFLFVGQGGGKENLEKMC
                     STLNLENVIFKPLQPYELLPALLNLADCHLVVQKKGAADAVLPSKLTNILAIGGNSVI
                     TAEENTELGQLCKNNPGIAQCVEPESVDALISGIEKCLLMPRHNDVAIKYANASLDMN
                     NVLSKFIMDIKI"
     gene            2659..4062
                     /gene="wcaJ"
                     /locus_tag="IT892_003939"
     CDS             2659..4062
                     /gene="wcaJ"
                     /locus_tag="IT892_003939"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014907232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HAP3137090.1"
                     /translation="MATLYHRTRSNANASLISMAQRFSDVVIIFLGLYLVCLINSVPF
                     EYQHALMSLLSLVIFQMIGGITDFYRSWRGVAFSTEYILIFKNWTLSLLIALGLLSLD
                     STIDTRFLFFIQWYLLVDIGFFVCRSVIRLISGLLRKFGYNTRRVAVVGSLPAGINLL
                     KSFIEQPWLGFVVKGIYDNIKLESAEYDNVPYAGNIDKLIQEAREGKIDRIYIAMSMR
                     DESKIKDVVRKLTDTTCSVLLIPDIFTFNILQSRTEEINGVPVVPLFDSPLNGINMVF
                     KRLEDIIVSSLILILISPILLVIATAVKTTSKGPVIFRQVRYGMDGKPIKVWKFRSMT
                     VMENDDKVIQATKNDIRVTKVGKFLRSTSLDELPQFFNVLFGQMSVVGPRPHAVSHNE
                     QYRSLIQGYMLRHKVKPGITGLAQINGWRGETDTLEKMEKRIEYDLLYIRGWSIWLDL
                     KIIFLTVFKGFINKSAY"
     gene            4226..5632
                     /gene="gndA"
                     /locus_tag="IT892_003940"
     CDS             4226..5632
                     /gene="gndA"
                     /locus_tag="IT892_003940"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAP3137091.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWELNYGEIAKIFRAGCIIRAQFLQKITDAYAQKAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLE"
     gene            5875..7290
                     /locus_tag="IT892_003941"
     CDS             5875..7290
                     /locus_tag="IT892_003941"
                     /EC_number="2.7.7.13"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019725197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="HAP3137092.1"
                     /translation="MLLPVIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITRL
                     SGLEIHEPMVICNEEHRFLVAEQLRQLNKLSNNIILEPVGRNTAPAIALAALQATRYG
                     DDPLMLVLAADHIINNQSAFHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVA
                     LTDSAHAPYQVARFVEKPDRERAEVYLASGEYYWNSGMFMFRAKKYLSELAKYRPDIL
                     ETCQAAVNAADNGSDFINIPHDIFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSW
                     SALWEVSPKDEQGNVFSGDAWVHNSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMN
                     RERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFS
                     MQMHHHRAEHWVILAGTGQVTVNGKQFLLSENQSTFIPIGAEHCLENPGCIPLEVLEI
                     QSGSYLGEDDIIRIKDQYGRC"
     gene            7314..8684
                     /gene="cpsG"
                     /locus_tag="IT892_003942"
     CDS             7314..8684
                     /gene="cpsG"
                     /locus_tag="IT892_003942"
                     /EC_number="5.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019725196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase CpsG"
                     /protein_id="HAP3137093.1"
                     /translation="MTQLTCFKAYDIRGELGEELNEDIAYRIGRAYGEFLKPGKIVVG
                     GDVRLTSESLKLALARGLMDAGTDVLDIGLSGTEEIYFATFHLGVDGGIEVTASHNPM
                     NYNGMKLVRENAKPISGDTGLRDIQRLAEENQFPPVDPARRGTLRQISVLKEYVDHLM
                     GYVDLANFTRPLKLVVNSGNGAAGHVIDEVEKRFAAAGVPVTFIKVHHQPDGHFPNGI
                     PNPLLPECRQDTADAVCEHQADMGIAFDGDFDRCFLFDDEASFIEGYYIVGLLAEAFL
                     QKQPGAKIIHDPRLTWNTVDIVTRNGGQPVMSKTGHAFIKERMRQEDAIYGGEMSAHH
                     YFRDFAYCDSGMIPWLLVAELLCLKNSSLKSLVADRQAAFPASGEINRKLGNAAEAIA
                     RIRAQYEPAAAHIDTTDGISIEYPEWRFNLRTSNTEPVVRLNVESRADTGLMNAKTEE
                     ILALLK"
     gene            8848..10014
                     /gene="ugd"
                     /locus_tag="IT892_003943"
     CDS             8848..10014
                     /gene="ugd"
                     /locus_tag="IT892_003943"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HAP3137094.1"
                     /translation="MKITISGTGYVGLSNGVLIAQNHEVVALDIVQAKVDMLNQKISP
                     IVDKEIQEYLAEKPLNFRATTDKHDAYRNADYVIIATPTDYDPKTNYFNTSTVEAVIR
                     DVTEINPNAVMIIKSTIPVGFTRDIKERLGIDNVIFSPEFLREGRALYDNLHPSRIVI
                     GERSARAERFADLLKEGAIKQDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYA
                     ESQGLNSKQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYESVPNNIIAAI
                     VDANRTRKDFIADSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIPVII
                     YEPVMQEDEFFNSRVVRDLDAFKQEADVIISNRMAEELADVADKVYTRDLFGND"
     gene            complement(10439..10561)
                     /locus_tag="IT892_003944"
     CDS             complement(10439..10561)
                     /locus_tag="IT892_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small membrane protein"
                     /protein_id="HAP3137095.1"
                     /translation="MENLFFLVVAAILLAVSVYFLISYLKDRKKTKLTFNKRKW"
BASE COUNT         2781 a         2339 c         2536 g         2920 t
ORIGIN      
        1 caataagatt atgtttctag gttcctcatg tatttatcct aaatttgcta agcaaccgat
       61 tagtgagtcc gaattactac aaggaacact tgaatcaacg aatgaaccgt atgctatagc
      121 aaaaatcgct ggtattaaac tctgcgagtc ctataatcga caacataatc gagattatcg
      181 ttcagttatg ccaactaact tgtatggaga aaacgataat ttccaccctt ctaattcgca
      241 tgtaattcct gcattactac gccgttttca tgaggcaaag ttagaaggtc taccacaagt
      301 tgttgtatgg ggtagtggaa ctccgatgcg cgagtttctg catgttgatg atatggctgc
      361 tgcatctatt tatgtcatgg agcttgataa agcactttgg caggagcaaa cacaaccaat
      421 gctttcacat attaacgtag gcactggcgt tgattgctct attaaagagt tagcggaaac
      481 aatttcaaaa gttgttggtt atcaaggggg ggtcgttttt gattctacca aacctgacgg
      541 cactcctaga aagttattag atgtttcgag attagaaggt ttaggctgga agcatcagat
      601 taatcttgaa gcaggcttgg cacggactta tgaatggttt ttaaaaaatc agaaaagttt
      661 ccggagttaa tatgttttta gatgacaatg catttaaaaa tataataagg aatacaccac
      721 ttatttcaat tgatttgatc attcaaaatg agaaagatga gtatttagtt ggtaaaagaa
      781 acaaccgccc cgcaaggggc ttttggtttg ttcctggagg gcgcatacta aaagatgagt
      841 cattggataa tggtttcgcc agactgaccc aaaatgaaat tggcattaaa atgatacgaa
      901 atgaaagcac ttttcttggt atctttcaac atttctatga tgacaatttt tttaataatg
      961 aatttagtac gcactatata gtattggcat ataaaacatc tattatctcc agcggtcttg
     1021 tatttccaca tgaacaacat aatgaatacc actggatggg tgtggatgaa atacttaata
     1081 atgatttagt acattttaat actaaagctt attttatgaa tgttgctttg gacttttaag
     1141 tatgaaatta cttgtatatg gcatcaatta tcgtcctgaa ttaactggta ttggcaagta
     1201 tagtggtgaa atggttaaat ggtttgttga taatgatctt gatgttagag tcattactgc
     1261 tccgccatat tatcctgcat ggaagattgc taataattat tctggatgga aatacacgaa
     1321 agaaaaacat cccgaaatag tatatagatg tcctctttat gtacctaaca aaccttctac
     1381 aataaagcgg ttattacatt tgtccagctt tgcattcagt tctttttttc ctcttttaat
     1441 gcaggctcgt tggaaacctg attatattat ctgcattgta cctactttat tttgtgtacc
     1501 aggggctctg ctattaagaa aactaactcg tgccaaggta ataattcata tacaagattt
     1561 cgaggttgat gctatgctcg gcttgggtat ggctaagaaa ggtgtgtttg ctacatttgc
     1621 caaaaagttt gaaaaatggt gcttaacgtc tgcagataaa gtatccacta tatctaaaac
     1681 aatgttatcg aatgcctccg gtaaaggtgt gccacagagt aatctaattt tttttcctaa
     1741 ctggtctgaa cttgaaagat ttaagaatgt tgacggtgta aagtcagttc agctgaaaga
     1801 agagtttgga attgctgaag acaaaaaagt tattctttac tcagggaata taggtgaaaa
     1861 gcaagggctt gaaattgtta tcagtgccgc gcagaaaatg gcatcaaata attttgtttt
     1921 cttatttgtt ggccagggtg gtggtaagga aaatttagag aaaatgtgct ctaccctcaa
     1981 tttggaaaat gtgattttta agcctttaca accttacgag ttattaccag cattattaaa
     2041 tcttgccgat tgtcatcttg tcgttcaaaa gaaaggtgca gctgacgctg ttctaccctc
     2101 taagcttacg aatatcttgg ctattggtgg taattctgtt atcactgcgg aagaaaacac
     2161 tgagcttggt caattatgca aaaataatcc tggtattgca caatgtgttg agcctgaatc
     2221 tgttgatgct ctcatttctg gtattgaaaa atgtttgcta atgccacgtc acaacgatgt
     2281 agcgataaaa tatgccaatg catcacttga tatgaataat gtcctttcaa aattcataat
     2341 ggatataaaa atataatatt taacattaac aaggagtgta gtatttaagt tacttctggt
     2401 ggaaaggatt cctcattttt atatcatcaa ttattatttc gtatgagtct ttcattaaac
     2461 gaagtaatat tatgaaattg gtggtgcttt ttaaagttaa tattgcagtc ctattttctt
     2521 cattacgact attatataat ctttattatg gtgtaagagt tcgagattaa ttaacgcatt
     2581 aacctttaat cttgtaaact tcaggatctc tattgcaaat tattatttca taaggttaaa
     2641 tattttaagg aaatcttcat ggcaaccttg tatcatcgga ctcgctcgaa tgcgaatgct
     2701 tctttgatct caatggctca acgcttttcc gatgtggtca taatcttttt gggattatat
     2761 ttggtatgtc ttattaattc agtcccattc gaataccaac atgccctcat gtctttacta
     2821 tcgttggtca ttttccagat gataggtggt ataactgatt tctatcgttc ttggcgtggc
     2881 gttgcgtttt ctacagagta tattttaata tttaaaaact ggacgcttag cttattaatt
     2941 gctttagggc ttttatcttt agactcaacg attgatactc gttttttatt ttttattcag
     3001 tggtacttgc tcgttgatat tggttttttt gtatgtcgct cagttatcag attgatctct
     3061 ggtttactta gaaaatttgg ctataatacc agaagagtgg ctgttgtcgg ctcattacct
     3121 gcaggcatta atttgctaaa aagctttatt gagcagcctt ggctaggctt cgttgttaaa
     3181 ggtatttacg ataatataaa attggaaagt gccgaatatg acaatgtacc ttatgctgga
     3241 aatatagata aacttattca ggaggcccgt gagggtaaaa tcgaccgtat ttatattgcg
     3301 atgagcatgc gcgatgagtc caaaataaag gatgtcgtta ggaaattaac agatacaact
     3361 tgttctgttt tgctaattcc tgatattttc acttttaaca tcctccagtc acgtacagaa
     3421 gaaattaatg gtgtaccggt tgttccatta ttcgattcac cgcttaatgg cattaatatg
     3481 gtctttaagc gtcttgaaga tataattgta tcatctttga ttcttattct gatatcacca
     3541 attcttctgg ttatagctac tgctgttaaa accacgtcga aagggccggt tattttccgc
     3601 caggtgcgtt atggaatgga cggaaaacct ataaaagtct ggaaatttcg ctcgatgact
     3661 gtgatggaaa acgacgataa agttattcag gctacaaaaa atgatatccg cgtgactaaa
     3721 gtcggcaagt ttttacgcag cacttcctta gacgaacttc cgcagttctt taatgtactt
     3781 tttggtcaga tgtccgttgt aggacctcga ccacatgcag tttctcataa cgagcaatat
     3841 cggtccttaa ttcaggggta tatgcttcgt cataaggtta agccaggtat cactggctta
     3901 gcacaaatta atggatggcg tggtgaaacg gatactttgg aaaaaatgga aaaaagaatc
     3961 gaatatgatt tgttatatat cagaggttgg agcatttggt tagatctaaa aataatattc
     4021 cttactgtct ttaaaggatt tattaacaaa tctgcttatt gatcagatgc tgcttaagac
     4081 aagctttgtg catttatagt ccaaaattta tatcttgtgc tagttaacaa attttcacta
     4141 tgagctcttt atactttggg ctaacattat tatcacattt aagctgcgaa cgtgtcgcag
     4201 tgaccacacc agacaggagt atgtaatgtc caagcaacag atcggggttg tcggtatggc
     4261 tgtgatgggg cgtaaccttg cgctgaatat cgaaagccgt ggttataccg tctccgtttt
     4321 caaccgctcc cgtgaaaaga ccgaagaagt gattgccgaa aacccaggca agaaactggt
     4381 tccttactac acagtacaag agtttgttga atccctcgaa acaccacgtc gtatcctgtt
     4441 gatggtgaag gccggggctg gcaccgacag cgccatcgat tccctgaagc cttacctcga
     4501 caaaggcgac atcatcattg atggcggcaa tactttcttc caggacacca tccgtcgtaa
     4561 ccgtgaactg tctgccgaag gttttaactt tatcggtacc ggtgtttccg gtggagaaga
     4621 gggggctctg aaagggcctt ccatcatgcc cggtggccag aaagaagcct atgagctggt
     4681 tgctccaatt ctgaagcaga ttgctgcggt tgctgaagac ggcgagccat gtgtcaccta
     4741 tatcggtgct gatggtgctg gtcattatgt aaagatggtt cataacggca tcgagtatgg
     4801 cgatatgcaa ctcattgcag aagcttatgc gctgttgaaa ggcggtctgg ctctttccaa
     4861 cgaagagctg gcgcaaacct tcaccgaatg gaacgaaggt gaactgagca gttacctgat
     4921 cgacattacc aaagatatct tcaccaagaa ggatgaagaa ggtaaatacc tcgttgatgt
     4981 cattcttgat gaagctgcaa acaaaggtac cggtaagtgg accagccaga gctcactgga
     5041 tctcggcgaa cctctgtctc tgatcaccga gtccgtattt gctcgttaca tttcttcgct
     5101 taaagaccag cgtgtagctg cttcgaaagt gctgagtggt ccgcaggctc aaccagccgg
     5161 cgataaagca gaatttatcg aaaaagtgcg tcgcgcgttg tacctcggta aaatcgtctc
     5221 ctatgctcag ggcttctccc agctacgagc tgcttctgat gaatacaact gggagctgaa
     5281 ctacggcgag atcgctaaga ttttccgcgc tggctgcata attcgtgcgc agttcctgca
     5341 gaaaatcacc gatgcttatg cgcaaaaggc tggcattgct aacctcctgc tggcgccgta
     5401 cttcaaacag atcgctgatg actatcagca ggcgctgcgt gatgtcgtgg cgtatgccgt
     5461 acagaatggt attccggtac cgacgttctc tgcggcaatt gcctactatg acagctaccg
     5521 ttccgcagtt ctgcccgcta acctgattca ggctcagcgt gattactttg gcgcgcacac
     5581 ttataagcgt actgataaag aaggtgtatt ccataccgag tggttggaat aatctttata
     5641 taccacagtc aggccaattg gcctgactgt tatctattgt tagttattct acaataatct
     5701 gatcaaagtc atcttatttg cacgcctgcg ttatttatcc agctctaata aaccaaatgc
     5761 tcatctttta agaatttgcc atatttatac ttttgtatac ctataataag ctgcttctgg
     5821 cctcagaata tatctgggtg tttaataaca gggttttaat taaaggatat taatatgttg
     5881 cttcctgtga taatggctgg cggtaccggc agtcgtctct ggccgatgtc tcgcgagctt
     5941 tacccgaaac agttcctccg cctgttcggg cagaactcca tgctgcagga aaccatcacc
     6001 cgactctcgg gccttgaaat ccatgaaccg atggtcatct gtaacgaaga gcatcgcttc
     6061 ctggtggctg aacagctgcg ccagctcaat aagctgtcga ataacattat acttgaaccg
     6121 gtcgggcgca acaccgcgcc ggccatcgcc ctggcggccc ttcaggccac ccgctacggt
     6181 gacgacccgc tgatgctggt cctcgccgcc gaccatatca tcaacaatca gtcggccttc
     6241 cacgacgcca tccgcgtcgc cgagcagtat gccgatgaag gccatctggt caccttcggt
     6301 atcgtgccga acgccccgga aaccggctac ggctacatcc agcgcggcgt ggcgctcacc
     6361 gacagcgccc acgccccgta ccaggtggcc cgcttcgtgg agaagccgga ccgcgagcgc
     6421 gccgaggtct acctcgcctc cggggagtac tactggaaca gcggcatgtt tatgttccgt
     6481 gccaaaaaat acctctccga gctggccaaa taccgtccgg atatcctgga aacctgccag
     6541 gctgcggtga atgccgccga taatggcagc gatttcatca atatcccgca tgatattttc
     6601 tgcgagtgcc cggatgagtc cgtggactac gccgttatgg agaaaaccgc cgacgcggtg
     6661 gtggtcggtc tcgatgccga ctggagcgat gtcggctcct ggtccgccct gtgggaggtc
     6721 agcccgaaag atgagcaggg caacgtcttc agcggcgacg cgtgggtgca caacagcgaa
     6781 aactgctaca tcaacagcga cgagaagctg gtggcggcca tcggcgtgga gaatctggtg
     6841 attgtcagca ccaaggacgc cgtgctggtg atgaaccgcg agcgttccca ggacgtgaag
     6901 aaggcggtcg agttcctcaa gcagaaccag cgcagcgaat acaagcgcca ccgcgagatt
     6961 taccgtccct ggggccgctg cgacgtggtg gtccagaccc cgcgcttcaa cgtcaaccgc
     7021 atcacggtga aacctggcgg tgccttctcg atgcagatgc accaccatcg cgctgagcat
     7081 tgggttattc tcgccggcac cggtcaggtg acggtcaacg gtaagcagtt cctgttgtcc
     7141 gagaaccagt ccacctttat tccgattggc gccgagcact gcctggaaaa ccctggctgt
     7201 attccgctgg aagtgctgga gatccagtcg gggtcgtacc tcggcgagga cgacattatt
     7261 cgtattaaag accagtatgg tcgttgctaa ttattttcgg gacaagatgc agaatgacac
     7321 agttaacttg ttttaaggct tatgacatcc gtggtgaact gggtgaggaa ctgaacgagg
     7381 acatcgccta ccgtatcggg cgcgcctacg gcgaatttct gaaacccggg aagatagtgg
     7441 tgggggggga tgtgcgcctc acaagcgagt cgttgaagct ggcgctggcc cgcgggttaa
     7501 tggacgccgg taccgatgtg ctggacatcg gactgagcgg cacggaagag atttacttcg
     7561 ccaccttcca cctcggggtg gacggcggca tcgaggtgac ggcgagtcac aacccgatga
     7621 actacaacgg catgaagctg gtgcgcgaga acgcgaagcc catcagcggc gacaccggcc
     7681 tgcgggatat ccagcgcctg gcggaggaga accagttccc gccggtggac ccggcacgtc
     7741 gcgggaccct gcgtcagatt tcggtgctga aggagtacgt cgaccacctg atgggctacg
     7801 tggacctggc gaacttcacc cgtccgctga agctggtggt gaactccggc aacggggcgg
     7861 cggggcacgt gattgatgag gtggagaaac gcttcgcggc ggctggggtg ccggtaacct
     7921 ttatcaaggt gcatcaccag ccggatggcc atttccctaa cggtatccct aatccgctgc
     7981 tgccggagtg ccgccaggat accgccgacg cggtgtgcga gcatcaggcc gacatgggga
     8041 ttgcctttga cggcgacttc gatcgctgct tcctgttcga tgacgaagct tcgtttatcg
     8101 aggggtatta cattgtcggc ctgctggctg aggcgttcct gcagaagcag ccgggagcga
     8161 aaatcattca cgacccgcgc ctgacgtgga atacggtaga catcgtgacc cgcaacggcg
     8221 gccagccggt gatgtcgaag acggggcatg cgttcatcaa ggagcggatg cgtcaggaag
     8281 acgctatcta cggcggggag atgagtgcgc accattactt ccgcgatttc gcctactgcg
     8341 acagcgggat gatcccgtgg ctgctggtgg cggagctgct gtgcctgaag aacagctcgc
     8401 tgaaatcgct ggtggcggac cgccaggcgg cgttcccggc gtcgggggag atcaaccgca
     8461 agctgggtaa tgcggcagag gcgatagcgc gcatccgggc gcagtatgag ccggcggctg
     8521 cccacatcga cacaacggac ggtatcagta ttgaataccc tgagtggcgc tttaacctgc
     8581 gcacgtccaa cacggagccg gtggtgcgtc tgaacgtgga gtccagagcg gatactgggt
     8641 taatgaatgc aaaaaccgaa gagattttag ctcttctcaa gtaatgcatt atccataatg
     8701 gaagccatag ggtcagattt taatcgtatt attgacctta tggcttattc ttgaaatacc
     8761 actggtcaaa gcgtaaaacc gcccacagta ttatttaatt tcgtggctat ccgccattat
     8821 ccagttaact gattaaagtg taatctcatg aaaattacta tttccggtac aggttatgtt
     8881 ggtttatcga acggtgtcct gattgcgcaa aaccacgaag tggttgccct ggatatcgta
     8941 caggctaaag tggatatgct taaccagaag atctctccga ttgtcgataa agaaattcag
     9001 gaatatctgg cagaaaaacc gttaaatttc cgtgccacca cggacaagca cgacgcctat
     9061 cgtaatgccg actacgtgat cattgcgacg ccgaccgatt atgatcccaa aactaactac
     9121 ttcaacacct ctacggtgga agcggttatt cgcgatgtca cagagatcaa cccgaacgcg
     9181 gtaatgatca ttaaatcgac catcccggtg gggttcaccc gcgacattaa agaacgttta
     9241 gggattgata atgttatttt ctctcctgag ttcctgcgtg aaggccgtgc gctgtacgac
     9301 aacctgcacc cgtcgcgtat tgtcatcggt gagcgctctg cgcgtgccga acgttttgct
     9361 gatctgctga aagaaggcgc gatcaagcag gatatcccaa ccctgtttac cgactccacc
     9421 gaagcggaag cgatcaaact gttcgctaac acctatctgg cgctacgcgt tgcttatttc
     9481 aacgagcttg acagctatgc tgaaagccag gggctgaaca gcaagcagat tatcgaaggg
     9541 gtatgcctgg atccgcgtat cggcaaccat tataacaacc cgtcctttgg ctacggcggc
     9601 tactgcctgc cgaaagatac caagcagctg ctggcgaact acgaatcggt cccgaacaat
     9661 atcatcgcgg ctatcgtcga tgccaaccgt acccgtaaag actttatcgc ggattctatt
     9721 ctcgctcgta agccgaaagt ggtgggtgta tatcgcctga tcatgaagag tggttcggac
     9781 aacttccgcg cctcttctat tcagggcatt atgaagcgca tcaaggcgaa aggtattccg
     9841 gttattatct atgaaccggt gatgcaggaa gatgagttct tcaactcccg cgtcgtgcgc
     9901 gacctggatg ccttcaaaca agaggcggat gtgatcatct ctaaccgtat ggcggaagaa
     9961 ctggcagatg tggcggacaa ggtttacacc cgcgatctgt ttggcaacga ttaatcctgt
    10021 ttgtctgtca ctggcggcct gccgccgcca gtgtgttcct ttatcccttc ctcatttctc
    10081 cttccccgag cctattttcc gctcattcag attaacctca ataaattgtg atggacatta
    10141 cgatcctgct caaaagccgt tgcgggttga aaacaggtcc gataagttaa acttaccttg
    10201 tgaagagcta ccgtcactgt gatgtagatg ccggagataa gcgccgggag gtaaaacaaa
    10261 gcctgcaacg caggcttttg ttatttatgt cctatgaaaa aacgagggac agggcgcgag
    10321 tagcgttatt ttttcttgcc ttaaggccat gccaaaacgc agaatgaata gtcattctgt
    10381 catatcattt ttttatctct taatattatc ttaatctaat tgcaatatga agtgggcctt
    10441 accacttgcg tttattaaac gtcagtttcg ttttctttct gtcttttaaa taagaaatta
    10501 agaaataaac ggaaacagca agtagtatgg cagcgaccac taaaaaaaat aggttttcca
    10561 taatatctac cacagg
//
LOCUS       DACAOP010000127        10388 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.127, whole genome shotgun sequence.
ACCESSION   DACAOP010000127 DACAOP010000000
VERSION     DACAOP010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10388
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.127"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            247..822
                     /gene="ssuE"
                     /locus_tag="IT892_003945"
     CDS             247..822
                     /gene="ssuE"
                     /locus_tag="IT892_003945"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HAP3137096.1"
                     /translation="MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAP
                     EDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVV
                     LPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTR
                     LDTALETFWQALHRRDVQVPDLLSLRGNAHA"
     gene            815..1774
                     /locus_tag="IT892_003946"
     CDS             815..1774
                     /locus_tag="IT892_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415456.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3137097.1"
                     /translation="MRNIIKLALAGLLSVSTFAVAAESSPEALRIGYQKGSIGMVLAK
                     SHQLLEKRYPESKISWVEFPAGPQMLEALNVGSIDLGSTGDIPPIFAQAAGADLVYVG
                     VEPPKPKAEVILVAENSPIKTVADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQP
                     TYLTPADARAAFQQGNVDAWAIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPY
                     AEKNGAFIQGVLATFSEADALTRSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKP
                     VNAEVAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQL"
     gene            1771..2916
                     /gene="ssuD"
                     /locus_tag="IT892_003947"
     CDS             1771..2916
                     /gene="ssuD"
                     /locus_tag="IT892_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMNH2-dependent alkanesulfonate monooxygenase"
                     /protein_id="HAP3137098.1"
                     /translation="MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGY
                     TGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGR
                     ALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLQRETVDFNGKHIHVRGA
                     KLLFPAIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPELVKEKIEQVRAKAAAH
                     GRKIRFGIRLHVIVRETNDEAWQAAERLISHLDDETIAKAQAAFARTDSVGQQRMAAL
                     HNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPH
                     LEEAYRVGELLFPLLDVAIPEIPQPQPLNPQGEAVANDFIPRKVAQS"
     gene            2927..3718
                     /gene="ssuC"
                     /locus_tag="IT892_003948"
     CDS             2927..3718
                     /gene="ssuC"
                     /locus_tag="IT892_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415454.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter permease
                     SsuC"
                     /protein_id="HAP3137099.1"
                     /translation="MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEG
                     VVTAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQ
                     MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARS
                     YGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREF
                     LQTDVVVVAIILYALLGKLADVSAQLLERLWLRWNPAYHLKEATV"
     gene            3715..4482
                     /gene="ssuB"
                     /locus_tag="IT892_003949"
     CDS             3715..4482
                     /gene="ssuB"
                     /locus_tag="IT892_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonates ABC transporter ATP-binding
                     protein"
                     /protein_id="HAP3137100.1"
                     /translation="MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVG
                     RSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVG
                     LGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPL
                     GALDALTRLEMQDLIVSLWQEHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVD
                     IPRPRRLGSVRLAELEAEVLQRVMQRGESETRLRKQG"
     gene            complement(4525..7137)
                     /gene="pepN"
                     /locus_tag="IT892_003950"
     CDS             complement(4525..7137)
                     /gene="pepN"
                     /locus_tag="IT892_003950"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HAP3137101.1"
                     /translation="MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVR
                     HGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEISPAA
                     NTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGN
                     RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRG
                     NLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYV
                     LARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL
                     GSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIH
                     TLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTV
                     KDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNS
                     VLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWD
                     AAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNE
                     MAELFDIIDPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRN
                     ACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWH
                     QNGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFH
                     AEDGSGYLFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLEN
                     LSGDLYEKITKALA"
     gene            7403..8605
                     /gene="pncB"
                     /locus_tag="IT892_003951"
     CDS             7403..8605
                     /gene="pncB"
                     /locus_tag="IT892_003951"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAP3137102.1"
                     /translation="MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGD
                     DLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSN
                     DNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSAL
                     TAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQ
                     AHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASR
                     YQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQL
                     SFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFD
                     LPHIKKAS"
     gene            8774..10174
                     /gene="asnS"
                     /locus_tag="IT892_003952"
     CDS             8774..10174
                     /gene="asnS"
                     /locus_tag="IT892_003952"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAP3137103.1"
                     /translation="MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDG
                     SCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQASKVEVAGW
                     VEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
                     STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGET
                     YACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKA
                     VLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAVTILENCGRKFENPVYWG
                     VDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIG
                     GSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQN
                     VRDVIPFPRTPRNASF"
BASE COUNT         2365 a         2648 c         2779 g         2596 t
ORIGIN      
        1 gtgacaaatc tttaatttat agatttcatg aatatttaaa tattaactga acgagtaatt
       61 cattgattca acatctaatg actatccaat aaataaatat gcgtgatata taaagccctt
      121 tctttagttt attttcagaa aaagatacac aaaatttata tttggaattt tcttgtctct
      181 ccgacagact gaccgaattg ttatcaatgt taacaaaaaa agaacaattg gttataagga
      241 gagagtatgc gtgtcatcac cctggcgggt agtcctcgct ttccttctcg ctccagctcc
      301 ttgctggaat atgcgcggga aaaactaaat ggcctggatg tagaggttta tcactggaat
      361 ctgcaaaact tcgccccgga agatctactt tatgctcgtt tcgatagtcc ggcactcaag
      421 accttcaccg aacagctgca acaggccgat gggctgattg tcgccacgcc tgtgtataaa
      481 gccgcctatt ccggtgcgtt gaaaaccctg ctcgacctgc tgccagaacg cgctttgcaa
      541 ggcaaagtgg tgctaccgct ggcgacgggc ggtaccgtgg cccatctgct ggcggtcgat
      601 tatgccctta aaccagtttt aagcgcactg aaagctcagg agatcctgca cggcgtgttt
      661 gccgatgact cacaagtaat tgattaccat cacagacccc agttcacgcc aaatctgcaa
      721 acccgtcttg ataccgcgct agaaactttc tggcaggcat tgcaccgccg cgatgttcag
      781 gttcctgacc ttctgtctct gcgaggtaat gcccatgcgt aacatcatta aactggcgct
      841 ggcgggattg cttagcgtct ctacttttgc ggttgctgca gaatcctcgc ctgaagcgtt
      901 acgtataggc tatcagaaag gcagtattgg tatggtgctg gcaaaaagcc accagttact
      961 ggaaaaacgc tatccggaat caaaaatctc ctgggtggag ttccccgcgg gtccgcaaat
     1021 gttggaagcg ttaaacgttg gcagtattga tctcggcagt accggggata ttccgccaat
     1081 ctttgcccag gctgccgggg ctgatttggt gtacgtgggc gtcgagccac cgaagcccaa
     1141 agccgaagtg attctggtgg cagaaaacag cccgatcaaa accgtagccg atcttaaagg
     1201 tcacaaagtt gcctttcaga aaggttccag ttcacacaac cttttactgc gtgcactgcg
     1261 tcaggccgga cttaagttta ccgatatcca acccacttac ctgacgcccg ctgatgcccg
     1321 cgccgcgttc cagcaaggta acgttgacgc ctgggctatc tgggatccct actactctgc
     1381 tgcattatta cagggcggcg tgcgggtgct gaaagacggc accgatctca atcaaactgg
     1441 atcgttttat ctggcagctc gtccctatgc agaaaaaaac ggcgctttta ttcagggcgt
     1501 actggcaacc tttagtgagg ccgatgcgtt aacccgcagc cagcgcgagc aaagcatcgc
     1561 tttactggca aaaacgatgg gcttaccggc accggtgatt gcctcttact tagatcatcg
     1621 ccctcctacc accatcaaac cggttaacgc cgaggttgcc gccttacagc agcaaacggc
     1681 agatctgttt tatgaaaatc gtctggtgcc gaaaaaagtc gatattcgcc agcgcatctg
     1741 gcagcccact caactggaag gaaaacaatt atgagtctga atatgttctg gtttttaccg
     1801 acccacggtg acgggcatta tctgggaacg gaagaaggtt cacgcccggt tgatcacggt
     1861 tatctgcaac aaattgcgca agcggcggat cgtcttggct ataccggtgt gctaattcca
     1921 acggggcgct cctgcgaaga tgcgtggctg gttgccgcat cgatgatccc ggtgacgcag
     1981 cggctgaagt ttcttgtcgc cctgcgtccc agcgtaacct cacctaccgt tgccgcccgc
     2041 caggccgcca cgcttgaccg tctctcaaat ggacgtgcgt tgtttaacct ggtcacaggc
     2101 agcgatccac aagagctggc aggcgacgga gtgttccttg atcatagcga gcgctacgaa
     2161 gcctcggcgg aatttaccca ggtctggcgg cgtttattgc agagagaaac cgtcgatttc
     2221 aacggtaaac atattcatgt gcgcggagca aaactgctct tcccggcgat tcaacagccg
     2281 tatccgccac tttactttgg cggatcgtca gatgtcgccc aggagctggc ggcagaacag
     2341 gttgatctct acctcacctg gggcgaaccg ccggaactgg ttaaagagaa aatcgaacaa
     2401 gtgcgggcga aagctgccgc gcatggacgc aaaattcgtt tcggtattcg tctgcatgtg
     2461 attgttcgtg aaactaacga cgaagcgtgg caggccgccg agcggttaat ctcgcatctt
     2521 gatgatgaaa ctatcgccaa agcacaggcc gcattcgccc ggacggattc cgtagggcaa
     2581 cagcgaatgg cggcgttaca taacggcaag cgcgacaatc tggagatcag ccccaattta
     2641 tgggcgggcg ttggcttagt gcgcggcggt gccgggacgg cgctggtggg cgatggtcct
     2701 acggtcgctg cgcgaatcaa cgaatatgcc gcgcttggca tcgacagttt tgtgctttcg
     2761 ggctatccgc atctggaaga agcgtatcgg gttggcgagt tgctgttccc gcttctggat
     2821 gtcgccatcc cggaaattcc ccagccgcag ccgctgaatc cgcaaggcga agcggtggcg
     2881 aatgatttta tcccccgtaa agtcgcgcaa agctaaggaa gaaataatgg caacgccagt
     2941 gaagaagtgg ttattgcgcg ttgccccctg gtttttaccg gtgggcatcg tggcggtgtg
     3001 gcaactggcc tcctcggttg gctggctgtc gacgcgtatt ttgccttcac cggaaggagt
     3061 ggtgacggcg ttctggacgc tctccgccag cggcgaactg tggcagcatc tggcgatcag
     3121 ctcctggcgg gcgctgattg gcttttcaat tggcggatcg ctggggttga ttttgggact
     3181 gattagcggg ctatctcgct ggggagaacg gctgctggat acctcaattc agatgttgcg
     3241 caacgtgccg catctggcgc tgatcccgct ggtgattttg tggtttggca ttgatgaatc
     3301 cgcaaaaatc tttctggtgg cgctcggtac gctattcccc atttatatca acacctggca
     3361 tggcatccgt aatatcgatc gcgggttggt ggagatggcg cgtagctatg gattatccgg
     3421 cataccgctg tttatccatg tgatcctgcc tggtgccctg ccctcaatta tggtcggcgt
     3481 gcgttttgcg ttgggcctga tgtggctgac gctgattgtt gccgaaacca tttctgccaa
     3541 ttcaggcatt ggttatctgg cgatgaatgc gcgggagttt ttgcaaacgg acgtggtggt
     3601 agtcgctatt attctttacg ccctgctcgg caaactggct gacgtcagcg cgcagctgtt
     3661 agagcgcctc tggttgcgct ggaacccggc ttatcatttg aaggaggcca cggtatgaat
     3721 actgctcgtc tgaaccaggg cacgccattg ttgctcaatg cagtaagcaa acattacgcg
     3781 gaaaatatcg tcctgaacca actggattta catattccgg caggtcagtt tgtggcggtg
     3841 gtgggccgca gcggtggtgg caaaagtacc ctgctgcgcc tgctggcagg tctggaaacg
     3901 ccaaccgcag gcgatgtgtt agcgggcacc acaccgctgg ctgaaattca ggaagacacg
     3961 cgaatgatgt ttcaggatgc gcgtctgcta ccgtggaaat cggtgattga taacgttggg
     4021 ttaggcctta aaggccagtg gcgcgatgcc gcacgtcgag cgttggctgc ggtaggactg
     4081 gagaatcgcg caggggaatg gcctgccgca ctttctggcg ggcagaaaca gcgagtggcg
     4141 ctggcaagag cgttgattca tcgaccggga ttattgttgc ttgatgaacc gctcggggcg
     4201 ctggacgcct taacgcgact cgagatgcag gatttgattg tgtcactttg gcaggagcac
     4261 ggctttaccg tactgttggt gacgcatgat gtgagcgaag cggtagcgat ggctgaccgg
     4321 gtgctgttaa ttgaagaggg aaaaattggt ctggatttga cagtggatat cccccgtccg
     4381 cgtcgattag ggtcggtgcg attagcggag ctggaagcgg aggtgttgca acgggtgatg
     4441 caacgtggtg aatctgaaac tcgcctgaga aaacaggggt aaattccccg aatggcggcg
     4501 ctattgccgc cattcggtta tttatcaagc cagtgcttta gttatcttct cgtacagatc
     4561 gccagagaga ttttccagcc ctttcaactg ttccagcgcc gcgcgcattt tctcctgacg
     4621 tttggcatcg taacgtttca ggcgaatcag cggttcaatc agacgtgaag ccacctgcgg
     4681 gttacggctg ttgaggtcgg taagcatttc caccaggaac aggtaaccgc tgccatcttc
     4741 ggcatggaac gctgccggat tgctgcccgc aaacgcgcca atcaacgaac gaatacggtt
     4801 cgggttgctc atggtaaatg agcgatgctg caacaggccg cgcaccgtct ccagcacatt
     4861 cgccgccggg ctggtggctt gcaggataaa ccatttatcc atcaccagac cgttctgatg
     4921 ccacttgtcg tcgtactcct gcatcagcgc gtcacggcaa ggcagctgtg cggcaaccgc
     4981 cgcagaaagc gccgccagcg catcagtcat attgtttgct tcgtggaact gcttgctcac
     5041 cagcacatca gccagatgcg tttcaccaaa agcgaggaaa cgcaggcagg cattacgcag
     5101 agtgcgtttt gcaatatctt catgctcaac acggtactcg ctctggtaat tcgcgttgta
     5161 aatagccagt agctcatccg ccagttcagt cgccagagta cgagtgagtg cttcgcgtac
     5221 ttcggcaata gcaatcgggt cgatgatatc gaacaattca gccatttcat tgacagaagg
     5281 cagcgtcagg atttctgccg ccagcgctgg atcaatcttc tcatcaagca gtaccgcgcg
     5341 gaaagcatca gccacatgca ccggcagaga cagcggctga ccttgctgat gacgcgcgac
     5401 gttcagcttg atgtaggttg ccagcaaact ttgcgccgca tcccagcggg agaaatcatt
     5461 acgcgcatga cgcatcagga aggtcagttg ctgatcgctc cacttatatt ccagtttcac
     5521 tggcgcagag aattcgcaca gcagcgcagg caccggctgg aagtagacat tatcaaagac
     5581 aaaggtctgt tccgcctgag tgacgttcag cacggaattc accggatgac cgcctttctg
     5641 caacgggatc actttgcctt cgttatcata cagttcgatg gcaaacggaa tatgcagcgg
     5701 ctgtttttct gcctgatccg gcgtggctgg cgtgcgctgg ctgatggtca gggtgtactg
     5761 ctcggtttcc ggattgtagt cgtctttgac ggtcacaatc ggtgtaccgg actggctgta
     5821 ccaacggcgg aaatgggaga gatcgacatt cgacgcatct tccatcgcct gcacaaagtc
     5881 gtcacaggtc gctgcactac catcatgacg ctcgaaataa agctgcatcc ctttctggaa
     5941 gttttcttcg ccaagcaggg tgtggatcat gcgaatcact tccgcgccct tctcgtaaac
     6001 ggtcagggtg tagaagttgt tcatctcaat gaccatatcc gggcggatcg ggtgcgccat
     6061 cgggctggcg tcttctgcaa actgcaatcc gcgcatggtg cgtacattat tgatgcggtt
     6121 aactgcgcgg gaaccaaggt cagagctgaa ctcctgatcg cggaagacgg ttaaaccttc
     6181 tttcaggctg agctggaacc agtcgcgaca ggtcactcgg ttaccggtcc agttatggaa
     6241 atattcatgg ccgataacgc gttcaatatc gaggtaatct ttgtcggtgg cggtgtcggt
     6301 gcgggccagc acatatttgg agttaaagat attcagcccc ttattctcca ttgcgcccat
     6361 attgaagaaa tccaccgcga cgatcatata gatgtcgagg tcatactcca ggccaaagcg
     6421 ttcttcatcc catttcatgg agtttttcag cgaggtcatc gcccacggcg cgcgatcaag
     6481 gttgccgcga tcgacgtaca gctccagtgc tacttcgcga ccagaacgcg tggtaaaggt
     6541 atcgcgcagt acatcaaagt cgcctgccac cagcgcaaac aggtagcacg gtttcgggaa
     6601 cgggtcctgc cactgtaccc aatggcgtcc gttttccagt tcgccttgcg caacgcggtt
     6661 accattggaa agcaggaagg gatatttgat tttatcggca ataattttgg tggtaaaacg
     6721 cgccagcacg tccgggcggt cgagataata cgtaatatgg cggaaacctt cggcttcaca
     6781 ctgggtgcaa agcgcatcgc ctgactgata aagcccttcc agcgcggtat tcgccgccgg
     6841 gcttatttca ttaatgatct taagcgtaaa acgctccggc aaattactga taaccagtgc
     6901 gccctcttct tctttccagg cggtccacgg ctcatcatta atatgaacag aaaccagttt
     6961 gaggtcttcg ccgttgagac gaaggggagc atctgatgca ccatgacgga cagcctggct
     7021 gaccgcggta acgaccgtct tttgcgcgtc gaggtcaaag gtcaagtcaa tatcagtaat
     7081 ctggtaatcc ggcgcacgat aatcgtgacg gtatttggct tgtggctgtt gagtcataaa
     7141 taacctttag catcttttat agagtctggt gttcagtcta ttcctgttgc gtaaatcgcg
     7201 ctatgcagaa tcttcatctt ttcaggtaca aacgccttta ttgctacatt tttataacat
     7261 acaccgcgta atgccatcga ccagaaaggt ggcatatggt gtgatcgggg ttcaataaat
     7321 tgcgaaacaa ggtatactcc agcagttcct gaagatgttt attgtactaa acgctcctgt
     7381 acgaggacgc tactgcgcac ctatgacaca attcgcttct cctgttctgc actcgttgct
     7441 ggatacagat gcttataagt tgcatatgca gcaagccgtg tttcatcact attacgatgt
     7501 gcatgtcgcg gcggagtttc gttgccgagg tgacgatctg ctgggtattt atgccgatgc
     7561 tattcgtgaa caggttcagg cgatgcagca cctgcgcctg caggatgatg aatatcagtg
     7621 gctttctgcc ctgcctttct ttaaggccga ctatcttaac tggttacgcg agttccgctt
     7681 taacccggaa caagtcaccg tgtccaacga taatggcaag ctggatattc gtttaagcgg
     7741 cccgtggcgt gaagtcatcc tctgggaagt tcctttgctg gcggttatca gtgaaatggt
     7801 acatcgctat cgctcaccgc aggccgacgt tgcgcaagcc ctcgacacgc tggaaagcaa
     7861 attagtcgac ttctcggcgt taaccgccgg tcttgatatg tcgcgcttcc atctgatgga
     7921 ttttggcacc cgtcgccgtt tttctcgcga agtacaagaa accatcgtta agcgtctgca
     7981 acaggaatcc tggtttgtgg gcaccagcaa ctacgatctg gcgcgtcggc tttccctcac
     8041 gccgatggga acacaggcac acgaatggtt ccaggcacat cagcaaatca gcccggatct
     8101 agccaacagc cagcgagctg cacttgctgc ctggctggaa gagtatcccg accaacttgg
     8161 cattgcatta accgactgca tcactatgga tgctttcctg cgtgatttcg gtgtcgagtt
     8221 cgctagtcgg tatcagggcc tgcgtcatga ctctggcgac ccggttgaat ggggtgaaaa
     8281 agccattgca cattatgaaa agctgggaat tgatccacag agtaaaacgc tggttttctc
     8341 tgacaatctg gatttacgca aagcggttga gctataccgc cacttctctt cccgcgtgca
     8401 attaagtttt ggtattggga ctcgcctgac ctgcgatatc ccccaggtaa aacccctgaa
     8461 tattgtcatt aagttggtag agtgtaacgg taaaccggtg gcgaaacttt ctgacagccc
     8521 tggcaaaact atctgccatg ataaagcgtt tgttcgggcg ctgcgcaaag cgttcgacct
     8581 tccgcatatt aaaaaagcca gttaatatca tcagggagct aatcggctcc ctttttttac
     8641 ctttaattcc gaaatctttc gctgcatttg cgaattctgc ttgtctgatt gcagatgcca
     8701 ggtaacatag gtatcccccc atttacgggt ggacaagtgt ttattttttc cgactattaa
     8761 cagagagaat attatgagcg ttgtgcctgt agccgacgta ctccagggcc gtgtagccgt
     8821 tgacagcgaa gtcaccgtgc gcggatgggt acgtacccgc cgagattcaa aagctggcat
     8881 ctccttcctc gccgtttatg acggttcctg ctttgatcct gtacaggctg tcatcaataa
     8941 ttctctgccc aattacaatg aagacgtcct gcgtctgacc accggctgct cggtcattgt
     9001 gacgggtaaa gtcgtggcgt cgccgggcca ggggcaacaa tttgaaattc aggccagcaa
     9061 ggttgaagtt gctggttggg ttgaagatcc agacacttac ccgatggcgg caaaacgcca
     9121 cagcattgag tatctgcgtg aagtcgctca cctgcgtccg cgcacaaacc tgattggtgc
     9181 cgtcgcgcgc gttcgccata cgctggcgca ggcgctgcat cgcttcttta acgagcaggg
     9241 attcttctgg gtttcaacgc cactgattac cgcatctgat accgaaggtg caggcgaaat
     9301 gttccgcgtt tctacgctgg atctggaaaa cctgccgcgt aacgatcagg gcaaagtgga
     9361 tttcgacaaa gacttctttg gtaaagagtc tttcctgacc gtatctggcc agttgaacgg
     9421 cgaaacctac gcttgcgcat tgtccaaaat ttataccttc ggcccgactt tccgtgctga
     9481 aaactccaac accagccgtc acctggcgga attctggatg ctggagccgg aagtggcgtt
     9541 tgctaacctg aacgatattg cgggtctggc tgaagccatg ctgaaatatg tcttcaaagc
     9601 ggttctcgaa gaacgcgctg acgacatgaa attcttcgct gaacgcgtag ataaagatgc
     9661 cgtttcacgt ctggaacgct tcattgaagc cgattttgcg caggtggatt ataccgacgc
     9721 agtgaccatt ctcgaaaact gcggcaggaa gtttgaaaac ccggtttact ggggagtcga
     9781 tctctcttct gagcatgagc gttatctggc ggaagaacac tttaaagcac cggtagtggt
     9841 taaaaactat ccgaaagata ttaaagcgtt ctatatgcgc cttaacgaag acggtaaaac
     9901 cgttgcggct atggacgttc tggctccggg catcggtgag atcattggtg gctcccagcg
     9961 tgaagaacgt ctggacgtgc tggacgagcg tatgctggaa atgggcctga ataaagaaga
    10021 ttactggtgg tatcgcgatc tgcgtcgcta cggtactgtt ccgcattcag gtttcggtct
    10081 tggttttgaa cgtctgattg cttacgtaac tggcgtgcaa aacgtacgtg atgtgattcc
    10141 gtttccacgt actccgcgta acgccagctt ctaatttagc gtcttcaaga gccagcgccc
    10201 gctggctctt tttttatctt ttctgtcaag ttatctgttt gttaagtcaa gcaatctatt
    10261 tgcaaccccg ccataacgat catcctgtta cggaatatta cattgcaaca tttacgcgca
    10321 aaaactaatc cgcattctta ttgcggatta gttttttctt agctaatagc acaattttca
    10381 tactattt
//
LOCUS       DACAOP010000128        10020 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.128, whole genome shotgun sequence.
ACCESSION   DACAOP010000128 DACAOP010000000
VERSION     DACAOP010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10020
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.128"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(2..77)
                     /locus_tag="IT892_003953"
     tRNA            complement(2..77)
                     /locus_tag="IT892_003953"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42..44),aa:Lys,seq:ttt)
     gene            complement(81..156)
                     /locus_tag="IT892_003954"
     tRNA            complement(81..156)
                     /locus_tag="IT892_003954"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(121..123),aa:Val,seq:tac)
     gene            complement(306..381)
                     /locus_tag="IT892_003955"
     tRNA            complement(306..381)
                     /locus_tag="IT892_003955"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(346..348),aa:Lys,seq:ttt)
     gene            complement(384..459)
                     /locus_tag="IT892_003956"
     tRNA            complement(384..459)
                     /locus_tag="IT892_003956"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Val,seq:tac)
     gene            complement(595..670)
                     /locus_tag="IT892_003957"
     tRNA            complement(595..670)
                     /locus_tag="IT892_003957"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(635..637),aa:Lys,seq:ttt)
     gene            complement(835..1626)
                     /gene="cpoB"
                     /locus_tag="IT892_003958"
     CDS             complement(835..1626)
                     /gene="cpoB"
                     /locus_tag="IT892_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein CpoB"
                     /protein_id="HAP3137104.1"
                     /translation="MSSNFRHQLLSLSLLVGIAAPWAAFAQAPISSVGSGSVEDRVTQ
                     LERISNAHSQLLTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVVERQKQILLQIDSLS
                     SGGAAAQSTSGDQSGAAASTTPTADAGTANAGAPVKSGNANTDYNAAIALVQDKSRQD
                     DAMVAFQNFIKNYPDSTYLPNANYWLGQLNYNKGKKDDAAYYFASVVKNYPKSPKAAD
                     AMFKVGVIMQDKGDTAKAKAVYQQVISKYPGTDGAKQAQKRLNAM"
     gene            complement(1636..2157)
                     /gene="pal"
                     /locus_tag="IT892_003959"
     CDS             complement(1636..2157)
                     /gene="pal"
                     /locus_tag="IT892_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HAP3137105.1"
                     /translation="MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGMLGAGTGMD
                     ANGGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSNPSYK
                     VTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDE
                     AAYSKNRRAVLVY"
     gene            complement(2192..3484)
                     /gene="tolB"
                     /locus_tag="IT892_003960"
     CDS             complement(2192..3484)
                     /gene="tolB"
                     /locus_tag="IT892_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolB"
                     /protein_id="HAP3137106.1"
                     /translation="MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQW
                     AGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVG
                     QVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIK
                     GAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVT
                     FESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLA
                     SGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQN
                     QDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYS
                     SSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL"
     gene            complement(3617..4882)
                     /gene="tolA"
                     /locus_tag="IT892_003961"
     CDS             complement(3617..4882)
                     /gene="tolA"
                     /locus_tag="IT892_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HAP3137107.1"
                     /translation="MSKATEQNDKLKRAIIISAVLHVILFAALIWSSFDENIEASAGG
                     GGGSSIDAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQER
                     LKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAA
                     KKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEK
                     AKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAA
                     AAKAAAEKAAAAKAAAEADDIFGELSSGKNAPKTGGGAKGNNASPAGSGNTKNNGASG
                     ADINNYAGQIKSAIESKFYDASSYAGKTCTLRIKLAPDGMLLDIKPEGGDPALCQAAL
                     AAAKLAKIPKPPSQAVYEVFKNAPLDFKP"
     gene            complement(4947..5375)
                     /gene="tolR"
                     /locus_tag="IT892_003962"
     CDS             complement(4947..5375)
                     /gene="tolR"
                     /locus_tag="IT892_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin uptake protein TolR"
                     /protein_id="HAP3137108.1"
                     /translation="MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVE
                     VDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKAN
                     PKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI"
     gene            complement(5379..6071)
                     /gene="tolQ"
                     /locus_tag="IT892_003963"
     CDS             complement(5379..6071)
                     /gene="tolQ"
                     /locus_tag="IT892_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolQ"
                     /protein_id="HAP3137109.1"
                     /translation="MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNA
                     AAREAEAFEDKFWSGIELSRLYQESQGKRDNLTGSEQIFYSGFKEFVRLHRANSHAPE
                     AVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
                     QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILH
                     RQAFTVSESNKG"
     gene            complement(6068..6472)
                     /gene="ybgC"
                     /locus_tag="IT892_003964"
     CDS             complement(6068..6472)
                     /gene="ybgC"
                     /locus_tag="IT892_003964"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HAP3137110.1"
                     /translation="MNTTLFRWPVRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHH
                     FSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQTEITSMRGTSLVFTQRIVNAENT
                     LLNEAEVLVVCVDPLKMKPRALPKSIVAEFKQ"
     gene            complement(6622..6915)
                     /gene="ybgE"
                     /locus_tag="IT892_003965"
     CDS             complement(6622..6915)
                     /gene="ybgE"
                     /locus_tag="IT892_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon protein YbgE"
                     /protein_id="HAP3137111.1"
                     /translation="MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTS
                     ELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF"
     gene            complement(6915..7028)
                     /gene="cydX"
                     /locus_tag="IT892_003966"
     CDS             complement(6915..7028)
                     /gene="cydX"
                     /locus_tag="IT892_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
                     /protein_id="HAP3137112.1"
                     /translation="MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI"
     gene            complement(7043..8182)
                     /gene="cydB"
                     /locus_tag="IT892_003967"
     CDS             complement(7043..8182)
                     /gene="cydB"
                     /locus_tag="IT892_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HAP3137113.1"
                     /translation="MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDT
                     ERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPV
                     GFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGN
                     FFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALA
                     GVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLP
                     LLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQ
                     LTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY"
     gene            complement(8198..9766)
                     /gene="cydA"
                     /locus_tag="IT892_003968"
     CDS             complement(8198..9766)
                     /gene="cydA"
                     /locus_tag="IT892_003968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HAP3137114.1"
                     /translation="MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSG
                     KQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLM
                     AFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFN
                     FETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKR
                     SFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPD
                     QEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSG
                     STDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRI
                     MVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQP
                     WAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGR
                     YHFEQSSTTTQPAR"
BASE COUNT         2445 a         2735 c         2406 g         2434 t
ORIGIN      
        1 ctggtgggtc gtgcaggatt cgaacctgcg accaattgat taaaagtcaa ctgctctacc
       61 aactgagcta acgacccgag tggtgggtga tgacgggatc gaaccgccga ccccctcctt
      121 gtaagggagg tgctctccca gctgagctaa tcacccgata ctgcgctgga tactacaaac
      181 tacttccacc gaacccaccg tcattagtgg tgggtcgtgc aggatgactc gcttcgctcg
      241 ccctacgggc cgttgctgac gcaacgttat cctacacgct taacatctgt cttcgatgtt
      301 aaaactggtg ggtcgtgcag gattcgaacc tgcgaccaat tgattaaaag tcaactgctc
      361 taccaactga gctaacgacc cggtggtggg tgatgacggg atcgaaccgc cgaccccctc
      421 cttgtaaggg aggtgctctc ccagctgagc taatcacccg atactacgct ggatactaca
      481 actaactatg ttagtggtgg gtcgtgcagg atgactcgac ttcgtctcgc ccttcgggcc
      541 gttgctcatg caacgttatc cttcacgttt tactaccgct tccaccttag cgattggtgg
      601 gtcgtgcagg attcgaacct gcgaccaatt gattaaaagt caactgctct accaactgag
      661 ctaacgaccc actttttcgt tgctttcggt ttgtttgata tcccgtggca acggcggcat
      721 atattactga tttcagactt gagcgcaaca aaaatttcga tgtagatcac tcaactgctt
      781 atgattcgca cgacacgacc agaaataatg cgacttctgg tcgtgtgtta tgcattacat
      841 cgcgttcaga cgtttttgtg cctgtttagc gccatcagta ccagggtatt tactgataac
      901 ctgctggtat acggctttcg cttttgcggt gtcacctttg tcctgcatga tgacgccgac
      961 tttaaacatc gcatctgcag cctttggtga cttcggatag tttttcacta ccgaagcaaa
     1021 atagtacgcc gcatcatctt ttttaccctt gttgtagttt aactgaccca gccaataatt
     1081 ggcgtttggc aggtaagttg aatcagggta atttttgatg aaattctgaa atgccaccat
     1141 tgcgtcatcc tggcgggatt tatcctgcac cagcgcaata gctgcattgt aatccgtgtt
     1201 tgcattaccg cttttcaccg gcgcgccagc attcgcagta ccagcatcag ctgtcggcgt
     1261 cgttgatgcc gccgcaccgc tttgatcgcc gctggttgat tgcgccgctg caccaccgct
     1321 gctgaggctg tcgatctgca acaggatctg cttttgccgc tccacgacct gattcagttg
     1381 atactgattt tcctgaatct gaccacgcag ggaatcaata tcggattgat tatcagaaag
     1441 ttgttgctgg agttgggtta aaagctggct gtgagcatta gaaatacgct caagttgagt
     1501 gacgcggtct tcgaccgagc ctgagccgac actactgatt ggtgcctgag caaaagcggc
     1561 ccagggggcc gctataccaa ccagtaacga cagactcaat agttgatgtc tgaagttact
     1621 gctcatgcaa ttctcttagt aaaccagtac cgcacgacgg tttttggagt atgccgcttc
     1681 gtcatgaccc agtactgcag gtttttcttt accgtaagaa acgatggaga tctggtctgc
     1741 agaaacgcct ttaccctgca ggtacatctt aacggcgttc gcacgacgtt cacccaggga
     1801 gatgttgtat tccggagtac cacgttcgtc cgcgtgacct tctacggtga ctttgtaaga
     1861 cgggttgcta cgcaggaagt ttgcatgtgc atccagcatt tgagcgaagt cagaacggat
     1921 atcgtacttg tccagatcga agtaaacgat gttgttctgc tgcagctgtt gcatttgcag
     1981 acgagcctgc tcttcggaag acatgttgcc gttgccgccg ttcgcatcca taccagtgcc
     2041 ggcacccagc atgccttcgc tgccgtcatt gctggcgttc ttgttggaag aacatgccgc
     2101 aattgccata acaggcagag caatcatcag ccctttcagc actttgttca gttgcatttc
     2161 aatgattcct ttactattca attaattatt atcacagata cggcgaccag gcagggaatt
     2221 tgacctgtcc atcagttgcc ggaagacgcg ctttgaaacg cccatcggta gaaaccaaat
     2281 tcagcacgga tcccatcccc tgagaagagc tgtagattac catagtgccg ttaggtgcca
     2341 gacttggcgt ttcatccagg aacgtggacg acagaacttg tacgcctccc gttgccagat
     2401 cttgtttggc aatgtgctgc tgcccaccat tggagctgac cattaccata aatttaccgt
     2461 cgctgctgac atccgcatcc tggttctgcg aaccttccca ggtaatacgt tgtggcgcac
     2521 cgccgttgat attcacttta taaacctgcg gacgaccggc ctggtcagaa gtaaatgcca
     2581 ggttctggct atccgggaac caggtcggtt cggtattgtt actgcgacca tcagtcacct
     2641 ggcggatctg accagaagcc aaatccatta cgtacaggtt cagactaccg gttttcgaca
     2701 aggcgaatgc cagtttgctg ccgtctggcg agaatgcagg tgcaccgttg tgacgcggga
     2761 atgaagccac ctgacgtaca gcgccatttg ccagcgtctg aataaccagc gcggaacgac
     2821 cgctttcgaa ggtcacataa gccagtttag aaccgtctgg tgaccacgcc ggagacatca
     2881 gcggctgcgg tgaacggtga acgacaaact ggttgtaacc gtcatagtca gatacgcgca
     2941 gttcatacgg gaactgaccg ccgttggtct gaacaacgta ggcaatacga gtacggaacg
     3001 cacctttaat gccggtcagt ttttcaaaca cttcatcact ggcggtatga ccagcataac
     3061 gcagccactg cttgttcact ttgtacgagt tctgagcaag tacagtaccc ggtgcgccgc
     3121 cagtgtcaac aagttgataa gcaacattgt aagaaccatc cggattcgga gtgacctgac
     3181 cgacaactac agcgtcaatg cccagtgcgg accatgcagc tggttgtact tcctgcgcac
     3241 tacccggctg ctgtggcaga cgagcgcgat ctaacggatt aaatttaccg ctgttacgca
     3301 agtcagcagc aacgatgccg ccaatatctt caggtgccgc accaggcccc gcccactgga
     3361 aaggaacaac accaatagga cgaccggaat ctacaccgct gtcgatcaca atgcggactt
     3421 cagcatgcag aactgatgcc cacagtatga gaaaaccaaa tgctactcgt aatgcctgct
     3481 tcatcatatc tcccttatct ggaccgatgg cccacgataa tttagcagaa tgttaacaaa
     3541 ctaaaataca caaaactacc agaaccccgt ggcaaccggt gcctgatgtt gaccgtccga
     3601 acagtcaaca tcgcgattac ggtttgaagt ccaatggcgc gtttttgaac acttcatata
     3661 ctgcctggct tggtggtttc gggatcttcg caagtttagc tgctgccaac gcagcctgac
     3721 aaagtgcggg atcgccacct tcaggtttga tatccagtaa cataccatcg ggtgccagtt
     3781 ttatgcgcag cgtacaggtt ttgcctgcat aggacgatgc gtcatagaac ttactttcga
     3841 tagcagattt aatctgcccg gcatagttat tgatatcggc ccctgatgcg ccattgtttt
     3901 tagtattacc actcccggca ggcgaagcat tgttcccttt cgcccctccc cccgttttcg
     3961 gtgcattctt accagagctt agctcaccga aaatatcatc tgcctctgcg gccgcttttg
     4021 ctgcagcggc tttttcagct gcagcttttg ccgctgccgc ttttttgtct gcggcggctt
     4081 tttctgccgc tgctttctta tcagctgctg ccttttcagc agccgctttt tctgctgctt
     4141 ttttgtcggc tgcagctttc tctgctgccg ctttcttatc agctgcagcc ttttcagcag
     4201 ccgctttctt ctcagcttct gctttggctt tttcagcagc ttcagttgcc gctttctttc
     4261 ttgcttcagc tgcagctgct tctgccgctt ccgctttctt cttcagtgcc gcagcggctg
     4321 cctcggcttt tttctgcgct tcggctgcgg ctttggcggc ttctgcttct gcttttttct
     4381 ttgcgtctgc agccgctttc ttcgctgctt cttccgcagc tttagcatct gcttcggcct
     4441 tcgctttagc atctgccgcc gctttcgctg ccgcctcttc agcttgcttc tgctttagct
     4501 cggcctgttt tgcggcttct tcagcctgct ttttctgctc ctgagccgct aaccgctctt
     4561 tctcaagttg cttcaggcgt tcctgttcag ccgcttgttt ctcacgcagt tcttcagcag
     4621 cctgctgttc cttcatcttg cgctgttcat cagaacgctt cgcgcttgat tcctggcttt
     4681 gcatgcgttt gtactgctca actaccgcac ctgaatcaac catgacagcg tcgatggacg
     4741 aaccaccgcc gcctccggct gaagcttcta tattctcatc gaacgaactc cagatcagcg
     4801 ccgcaaataa gatgacatgc agcactgctg aaataattat cgcccgcttg agcttgtcgt
     4861 tttgttcggt tgcctttgac actctcggtt tccaaaaact gttcgcctgt tacccgctct
     4921 ctttcaagca agggaaacgc agatgtttag ataggctgcg tcattaaacc aaccgatttc
     4981 acacccgcac tatgtaacaa gttcagtgct ttaattattt catcgtaagg cacatctttt
     5041 gcgccaccga tcagaaagac cgttttcggg ttggccttga aacggctgga cacttccgcc
     5101 accacctgct ctggtggtaa acgctccagg cgatctttct caaccaccac ggtgtactga
     5161 ccaataccag acacttcaac aatcactggc ggattatcgt tactgctcac cgcctgtgat
     5221 tcagtagcgt ctggcagatc gacctccacg ctctgggtga tgatgggcgc tgtcgccata
     5281 aagatcagca acagcaccag cagtacgtcc agcaacggta caatgttgat ttcggacttg
     5341 agatcgcgac gacctcgtcc acgcgctctg gccatggctt accccttgtt gctctcgcta
     5401 acggtaaacg cctggcggtg cagaatcgcg gtaaactctt ccataaagtt gtcgtaattc
     5461 agttccagtt tgtttacgcg ctggttgagg cggttgtagg ccataactgc cgggatagcg
     5521 gcaaacagac caattgcagt cgcaatcaac gcttctgcga taccgggcgc aaccatttgc
     5581 agtgttgctt gttttaccgc cccgagggcg ataaaggcgt gcatgatccc ccagaccgta
     5641 ccaaacagac caatatacgg gctgatggag ccaaccgtac cgaggaacgg aatgtgcgtt
     5701 tccagatttt caagttcacg gttcatggag atacgcatag cacgcgacgc cccttccact
     5761 acggcttccg gcgcatggct attggcacga tgcaggcgca caaactcttt gaacccgctg
     5821 taaaagattt gttccgaacc agtcagatta tcccgtttcc cctggctctc ttgatagagg
     5881 cgagagagtt cgattccaga ccagaattta tcttcaaacg cttcggcttc gcgcgccgct
     5941 gcgttaagaa tacgggtccg ctggataata atggcccaag atgcgattga aaaaccaatc
     6001 aaaatcaaca tgataagttt aaccagaagg ctagccttca ggaacaaatc aaggatattc
     6061 atgtcagtca ctgcttaaac tccgcgacaa tagacttggg aagcgcacga ggcttcattt
     6121 tgagtgggtc aacgcaaaca accagaacct ctgcttcatt cagcaaagta ttctcggcgt
     6181 tgacaatacg ttgcgtgaaa accaaagagg tgccacgcat tgatgttatt tcagtctgta
     6241 tttcgagcat atcgtcgagc cgcgcaggtg cgtaatattc caccgtcatt ttacgtacca
     6301 caaaggcaac gcgttcagcc atcagcgcct gctgactgaa gtgatgatga cgcagcatct
     6361 ctgtgcgtgc tctttcataa aaagcgacgt aactggcgtg gtacaccaca ccaccggcat
     6421 cggtatcttc atagtagacg cgaaccggcc atcgaaacag cgttgtattc actttacatc
     6481 ccggtaatgc aacaaaagtt agagctttta aacgctgcta ctatacgcgc gcgattgagg
     6541 tttgggaatg agggcaagtt aagggagcgt aaaaatttat gggcctggag cggcccataa
     6601 ttttttaaag agaattctga tttaaaagaa gaagaaaatc agcccgacaa tgagaacaat
     6661 atcggcaagc aatgggcaaa aaatcccttg ccaaagaacc ttctgcggac gaaagcccac
     6721 gccgtgaatc acaccagcac agacggccca catcagcaat aaaccatgcc agatttccag
     6781 ttcactggtc ttcgcggcaa aacgagatgg gtcccaaaac atacatcctg ctaacagaag
     6841 cgccatcacg aaggaaagcg cccgcagggg gcgcttgtcc attaccgcat acaaagtcgc
     6901 gataatctta ctcatcagat gtcttcttga ccggctttgc ctgattcgac gtgttcaagc
     6961 gccagcgcgg tgattacccc aaacgaacag gcaagaagcg ttcccagaat ccatgcgaaa
     7021 taccacattt ttagctcctt acttagtaca gagagtgggt gttacgttca atatcttctt
     7081 tggtgatacg accgaacatt ttccagtaac accaggcggt gtagagcaga atgatcggta
     7141 ccagaaccac cgcaacccag gtcatgacgt taagcgtcag ctggctggaa gttgcatccc
     7201 acattgtcag acttgcgttc atcatggtgc tggacggcat cacaaacggg aacattgcga
     7261 taccggctgt caggatgatg caggccagcg tcagggagga gaacacaaac gcccacgcgg
     7321 ctttatccat acgtgcagtc aggatggtca gcagcggcag aaccacaccc agtgccggaa
     7381 tagcccacag aattggcgtg ttgttgaagt taaccagcca tgcgccagct tcacgaacca
     7441 cttctttatt cagtgggtta gaggctgcgt aatggtccat tgtcgatttc acgacataac
     7501 catcgatacc gtacatcacc catacgccag ccagtgcgaa acagaccagt gtcaccagcg
     7561 cagccacctg agccgttgca cgggtacgca ggtgcagttc gcccacggta cgcatttgca
     7621 gataggttgc gccctgagta atgatcatcc ctacgctcac cacgcctgcc agcaggccga
     7681 acgggttaag caactggaag aagttaccgg tgtagtacag acgcagatat tcatcaacgt
     7741 tgaacggtac gccctgcaac aggttaccga acgctacacc aattaccagc ggcggaacga
     7801 agctaccaat gaagatgccc cagtcccaca tgttacgcca gcgggtttct tcaatcttgg
     7861 agcggtagtc aaaaccgacc ggacggaaga acaaagacgc cagcacgagg atcatcgcca
     7921 catagaagcc ggagaacgca gcggcataga ccatcggcca ggcagcaaag agtgcgccgc
     7981 ccgcggtgat cagccaaacc tggttaccgt cccagtgtgg tgcaatggag ttaatcataa
     8041 ttcgacgctc ggtgtcgtta cgaccgagga aacgggtgag catgcccacc cccatgtcga
     8101 aaccgtcagt gactgcaaaa ccaatcagca gaacgccaac cagcagccac cagataaaac
     8161 gcaatacttc ataatcgatc atttgacgac tcctgtctta gcgtgccggc tgagtagtcg
     8221 tggaagactg ctcaaagtga tagcgaccgg ttttcaggct gcttgggccg aggcgtgcaa
     8281 acttgaacat taagaacaat tctgccacca ggaacagggt atacaggccg caaatcagca
     8341 ccattgagaa gatgagatcg cctgcggtca gtgacgagtt cgccacagct gtcggcagca
     8401 cttcaccgat agcccacggt tggcggccat attcagccac gaaccagccc gcttctacag
     8461 caatccacgg cagcggaata ccgtacagcg cggcgcgcag aagccatttt ttctcgccaa
     8521 tgcggttgcg gatgacactc cagaaagaga gcgcgatgat tgccagaagc aggaagccac
     8581 acgccaccat gatacggaac gcaaagtaca gcggcgctac acgcgggatg gagtctttgg
     8641 ttgcctgttg aatctgcgct tcagtcgcat cagccacgtt tggcgtatag cgtttcagca
     8701 gcagaccgta accgaggtct ttcttcatgc tattgaactg gtcacgaacc gcctggtcgg
     8761 tagaaccaga acgcagttgt tcgagcagag agtacgcctt catcccgtta cgaatgcgtt
     8821 cttcatgctg caccatcagc tctttcaggc cgataaccgg ggtatccacg gaacgcgttg
     8881 caatgatgcc cagtgcgtaa gggatctgaa tcgcaaattt gttcgtctcc tcttcctgat
     8941 caggaatgcc gaacagagta aaggcagcag gcgcaggttg cgtttcccac tcggcttcaa
     9001 tagcagccag tttggttttc tgcacgtcgc ccatttcgta gccggattca tcacccagaa
     9061 caataacaga cagaacagca gccataccga agctggcagc gatagcaaag gagcgtttag
     9121 cgaaggcgaa gtcacgacct ttcagcatat accatgcgct gataccgagg atgaacatcg
     9181 cgccagtcac ataaccagac gctacagtgt gaacgaattt cacctgagca accgggttaa
     9241 gcaccagctc ggagaagctc accatctcca tacgcatagt ttcaaagttg aaatcggacg
     9301 cgattgggtt ttgcatccag ccgttcgcaa ccagaatcca cagtgcggac aggtttgaac
     9361 cgagcgccac cagccaggtg acacacatat gctgaacttt acccagacga tcccaaccga
     9421 agaagaacag acctacaaag gtggattcga ggaagaaggc catcagacct tcgattgcca
     9481 gcggcgcacc gaagatatcc cctacatagt gggaatagta agaccagtta gtcccgaact
     9541 ggaactccat ggtcagaccg gtagccacac ccagagcgaa gttgatacca aacaacttgc
     9601 cccagaactt ggtcatatct ttataaatct gtttgccgga gaggacgtag accgtttcca
     9661 taatggccag caggaacgcc ataccgagcg tcagtggcac aaaaaggaag tggtacatcg
     9721 cggtcaaggc aaactgtaag cgcgacagtt cgactatatc taacatcatg actccttgct
     9781 catcgcatga agactccgag agtgaacccc gttagaaagg gtcacacgca tgccccaata
     9841 gaaatttgtt tgaacacttt catcatacca tgtgaatgca cacaaaaacg gcgtaaagaa
     9901 aggttgcaaa catgttaata aaaactcaaa ttgatcccac gtatatatta cgccgcaaaa
     9961 tccttacaat aaacaggttt ttgttgaagc aaatttgcat ttttcgacgg tgatcaattt
//
LOCUS       DACAOP010000129         9768 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.129, whole genome shotgun sequence.
ACCESSION   DACAOP010000129 DACAOP010000000
VERSION     DACAOP010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9768
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.129"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            217..1167
                     /locus_tag="IT892_003969"
     CDS             217..1167
                     /locus_tag="IT892_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase family protein"
                     /protein_id="HAP3137115.1"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHKREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSDSQRDELQKANPDWCFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTDAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT"
     gene            1177..2559
                     /locus_tag="IT892_003970"
     CDS             1177..2559
                     /locus_tag="IT892_003970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP3137116.1"
                     /translation="MKESNSRREFLSQSGKMVTAAALFGTSVPLAHAAVAGTLNCEAN
                     NTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQTVEIQDGKIVALRENKLHPDAT
                     LPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
                     YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQAGFECEIVAFP
                     QHGLLLSKSEPLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHL
                     HETTPAGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDELANRMVVQQISI
                     ASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNE
                     QNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHK
                     GQLVGGSVAG"
     gene            2936..3985
                     /gene="yahK"
                     /locus_tag="IT892_003971"
     CDS             2936..3985
                     /gene="yahK"
                     /locus_tag="IT892_003971"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase YahK"
                     /protein_id="HAP3137117.1"
                     /translation="MKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDL
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALG
                     ADEVVNSRNADEMAAHLKSFDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     gene            4228..5043
                     /locus_tag="IT892_003972"
     CDS             4228..5043
                     /locus_tag="IT892_003972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137118.1"
                     /translation="MISLKAPHNNLMPYTQQSILNTVKNNQLPEDIKSSLVSCVDIFK
                     VLIKQYYDYPYDCRDDLVDDDKLIHLMAAVRDCEWSDDNALTINVQFNDFPGFYDWMD
                     YPDHPVKFVFRILENQKGTVWVYDQDDAFLDIKANVQAGRFTGLKKLVQFIDSVRTDC
                     KCILLEYHMPLLRIFPKGKECMHVEKWLREMSSIPETDAPIKQALAHGLLLHLKNIYP
                     VFPESLVMLLLSVLDVKTYRDDARLNEWISNRVQELGDRYYPVNKHVKIRYTL"
     gene            5456..5701
                     /locus_tag="IT892_003973"
     CDS             5456..5701
                     /locus_tag="IT892_003973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137119.1"
                     /translation="MAVQLFKTLLNQIPLLSSLQSGTLPLFGYSGWGRPMKKAHTGES
                     GLKWEAKDSSKLIGNKDHALRGLSSPMAVIRQIRLIT"
     gene            complement(5718..6389)
                     /locus_tag="IT892_003974"
     CDS             complement(5718..6389)
                     /locus_tag="IT892_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HAP3137120.1"
                     /translation="MMQLVHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQT
                     SLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAW
                     CSMRRQSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTW
                     ARLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYE
                     GVTQR"
     gene            6536..6811
                     /locus_tag="IT892_003975"
     CDS             6536..6811
                     /locus_tag="IT892_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HAP3137121.1"
                     /translation="MKIISKMLVGALALAVTNVYAAELMTKAEFEKVESQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
     gene            complement(6909..8495)
                     /gene="prpR"
                     /locus_tag="IT892_003976"
     CDS             complement(6909..8495)
                     /gene="prpR"
                     /locus_tag="IT892_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein
                     PrpR"
                     /protein_id="HAP3137122.1"
                     /translation="MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQL
                     GFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGK
                     LTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
                     LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDM
                     LGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSH
                     PFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLP
                     LQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMQQGRFRRDLFYRLSILR
                     LQLPPLRERVADILPLAESFLKVSLAALSAPFSAALRQGLQASETVLLHYDWPGNIRE
                     LRNMMERLALFLSVEPTPDLTPQFMQLLLPELARESAKTPAPRLLTPQQALEKFNGDK
                     TAAANYLGISRTTFWRRLKS"
     gene            8734..9624
                     /gene="prpB"
                     /locus_tag="IT892_003977"
     CDS             8734..9624
                     /gene="prpB"
                     /locus_tag="IT892_003977"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HAP3137123.1"
                     /translation="MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     LMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYES
                     INYYQYEEKLDNLFARSQVK"
BASE COUNT         2512 a         2390 c         2551 g         2315 t
ORIGIN      
        1 tgcggcgtgg acgccttatc cggcctacga gtggcgcgag aatctgtagg cctgataagc
       61 gtagcgcatc aggcatttgt caccattgcc ggatgcggcg tgaacgcctt atccggccta
      121 cgagtggcgc gagaattgta ggcctgataa gcgtagcgca tcaggcagtc tggcgttggt
      181 cataacccca tcaccctctg tagcggacat aacaacatga aagagcttgt ggtcgttgcc
      241 attggtggca acagcattat caaagataac gccagccagt cgattgagca tcaggcggag
      301 gcggtgaaag ccgtcgccga tacggtgctg gaaatgctgg cttccgatta cgacattgtg
      361 ctgacccacg gcaacgggcc gcaggtcggg ctggatttac gccgtgcgga gattgcccac
      421 aagcgcgaag ggctgccctt aacgccgctg gcgaactgtg tggcagatac gcagggcggc
      481 atcggctatc tgatccaaca ggcgctgaat aaccggctgg cgcgtcacgg cgagaagaaa
      541 gccgtcaccg tggtgactca ggtggaagtg gataaaaacg atccaggttt tgcccatccc
      601 accaagccca tcggcgcatt ctttagtgac agccagcgtg acgaattaca aaaggcaaac
      661 cctgactggt gttttgttga agatgccggg cggggctatc gccgcgtggt cgcctcgccg
      721 gaaccgaaac gtattgtcga agcacctgcc attaaagcgc tgatccaaca aggttttgtc
      781 gtaattggcg cgggcggcgg tggaattccg gtagtgcgta ctgacgcggg agattaccaa
      841 agcgtggacg cggttatcga caaagatctc tctaccgcgc tgctggcccg tgaaattcac
      901 gccgacattc ttgtgatcac cactggcgtc gaaaaagtgt gtattcactt tggcaaaccg
      961 cagcagcagg cgctcgatcg ggtggatatt gccaccatga cccgctatat gcaggaaggg
     1021 catttcccgc ccggcagcat gttgccaaaa atcatcgcca gcctgacatt tttagaacaa
     1081 ggcggcaaag aagtgattat caccacgccg gaatgcctgc ctgcggcgct gcgcggcgaa
     1141 acgggcactc atattattaa aacgtaagga cgtaagatga aagaaagcaa tagccgccgt
     1201 gaatttctga gccagagcgg taagatggtc accgccgccg cgctgtttgg tacctctgtg
     1261 ccgctcgccc atgcggcggt agctggcacc ctaaactgcg aagcgaacaa caccatgaaa
     1321 atcactgacc cgcattacta tctcgataac gtgctgctgg aaaccggttt tgactacgaa
     1381 aatggcgtgg cggtgcagac ccgcacggcg cgccagaccg tggagattca ggacggcaaa
     1441 attgtcgccc tgcgcgagaa caagctgcat ccggacgcca cgctgccgca ctatgacgct
     1501 ggcggtaagc tgatgctgcc caccacccgc gacatgcata ttcatctcga caaaaccttt
     1561 tacggcgggc cgtggcgctc gctcaatcgt ccggcaggca ccaccatcca ggacatgatc
     1621 aaactcgagc agaaaatgct gccggaactg caaccgtaca ctcaggagcg ggcagaaaaa
     1681 ctgattgatt tattgcagtc gaaaggcacc accattgccc gcagccactg caatatcgaa
     1741 ccggtttccg gcctgaaaaa tctgcaaaat ttgcaggcgg tgctggcgcg acgtcaggcg
     1801 ggctttgagt gtgaaatcgt cgccttcccg cagcacggtt tgctgctgtc gaaatctgaa
     1861 cctttaatgc gtgaagcgat gcaggcgggg gcgcattacg tcggcggcct ggacccgacc
     1921 agtgttgatg gcgcgatgga aaaatccctc gacaccatgt tccagattgc gctggactac
     1981 gacaaaggcg tcgatattca cctgcacgaa accactccgg caggcgtggc agccatcaat
     2041 tatatggttg aaacggtaga gaaaacgcca cagctgaagg gcaagctgac catcagtcac
     2101 gcctttgcgc tggcaacgct caacgagcaa caggtagatg aactggcgaa ccggatggtg
     2161 gtgcaacaaa tttctatcgc ctcgacggtg ccgattggca cgctgcatat gccgctcaaa
     2221 cagttgcacg acaaaggcgt aaaagtgatg actggcactg acagcgttat cgaccactgg
     2281 tcgccttatg gtctgggcga catgctggaa aaagccaatc tgtacgcgca gctctatatt
     2341 cgtcctaacg aacagaacct ctcccgctcg ctgtttttag ccactggcga tgtattgccg
     2401 ctgaatgaaa aaggcgagcg tgtatggcca aaagcgcagg atgacgccag ctttgtgctg
     2461 gtggacgcct cctgttccgc cgaggcggtg gcgcgtatct cgccgagaac cgcaacgttc
     2521 cataaagggc aactggtggg ggggagtgtg gcaggttgat gcgcatttga aacgcctgca
     2581 acggtgaata gtaagagatt taagccccag ggagtggggc aatctgaata tgagtgtgtc
     2641 ggcagaaatg gacattatct ttgaggaata tgcccttatt gacgttgtgt agataactat
     2701 ttgtctacgt gaaaagatca tcagttttgc cgattttagt cttttacaga tagcaaatat
     2761 cacacttaca ggcgctcgcc ttatggggaa cgttgctgct ctgtttcatt caggctcgcg
     2821 gcatgttggg gctggatcgg gtggtttaaa tattggctat attcaatgga cgcgttttgc
     2881 cgcgatgaca tatcaggcgt tgccaaatac acatagctaa tcaggagtaa acacaatgaa
     2941 gatcaaagct gttggtgcat attccgctaa acaaccactt gaaccgatgg atatcacccg
     3001 gcgtgaaccg ggaccgaatg atgtcaaaat cgaaatcgct tactgtggcg tttgccattc
     3061 cgatctccac caggtccgtt ccgagtgggc ggggacggtt tacccctgcg tgccgggtca
     3121 tgaaattgtg gggcgtgtgg tagccgttgg tgatcaggta gaaaaatatg cgccgggcga
     3181 tctggtcggt gtcggctgca ttgtcgacag ttgtaaacat tgcgaagagt gtgaagacgg
     3241 gttggaaaac tactgtgatc acatgaccgg cacctataac tcgccgacgc cggacgaacc
     3301 gggccatact ctgggcggct actcacaaca gatcgtcgtt catgagcgat atgttctgcg
     3361 tattcgtcac ccgcaagagc agctggcggc ggtggctcct ttgttgtgtg cagggatcac
     3421 cacgtattcg ccgctacgtc actggcaggc cgggccgggt aaaaaagtgg gcgtggtcgg
     3481 catcggcggt ctgggacata tggggattaa gctggcccac gcgatggggg cacatgtggt
     3541 ggcatttacc acttctgagg caaaacgcga agcggcaaaa gccctggggg ccgatgaagt
     3601 tgttaactca cgcaatgccg atgagatggc ggctcatctg aagagtttcg atttcatttt
     3661 gaatacagta gctgcgccac ataatctcga cgattttacc accttgctga agcgtgatgg
     3721 caccatgacg ctggttggtg cgcctgcgac accgcataaa tcgccggaag ttttcaacct
     3781 gatcatgaaa cgccgtgcga tagccggttc tatgattggc ggcattccag aaactcagga
     3841 gatgctcgat ttttgcgccg aacatggcat cgtggctgat atagagatga ttcgggccga
     3901 tcaaattaat gaagcctatg agcgaatgct gcgcggtgat gtgaaatatc gttttgttat
     3961 cgataatcgc acactaacag actgaaaaaa ttaataaata ccctgtggtt taacatatta
     4021 acttcgctct ccacttaact ttttagttaa ggagagcgaa ataatatcaa agtagcagta
     4081 aaacctataa cgtaaattta aattgttaaa ttaacgccct ccagtacaca atacttcaca
     4141 cgttagttat gagcgatttc tgatagtgcc tggtttaatc agagctttat tatctgcgac
     4201 gtttattttt atttaagaga gatcgcgatg atatcattaa aagctccgca caataatttg
     4261 atgccatata cgcaacaaag catacttaat acggttaaaa acaatcagtt accagaggat
     4321 atcaaaagct ccctggtttc ctgtgtcgat atattcaagg ttttgattaa acaatattat
     4381 gattatcctt atgattgtcg tgatgattta gtcgatgacg acaaactcat tcatctcatg
     4441 gctgccgtac gagactgtga gtggtcagac gataacgcac tcaccataaa tgtgcagttt
     4501 aatgatttcc ctggatttta tgactggatg gattaccctg atcacccggt taagtttgtt
     4561 tttcgcatac ttgaaaatca aaaagggaca gtttgggtat atgaccagga tgatgcgttt
     4621 cttgatatta aagcaaacgt gcaggctgga cgctttaccg ggcttaagaa attagtgcag
     4681 tttatcgatt cagtgcgaac agattgcaaa tgtattcttc ttgaatacca tatgcctttg
     4741 ctgagaattt tccctaaagg gaaagagtgt atgcatgtgg aaaaatggct tcgcgaaatg
     4801 tcgtctattc cggagacaga cgcgcccatt aagcaggcgc ttgcgcatgg attattatta
     4861 cacttaaaaa atatctaccc tgtttttcct gaatcactgg tgatgttatt gctctctgtt
     4921 ctggacgtaa aaacatacag agatgatgcg cgattaaatg aatggatatc taatagagtg
     4981 caggaattag gtgacagata ttatcctgta aataagcacg ttaaaatccg ctacactctt
     5041 tagttcagaa agggttccac ctgcaagttg ttattccacc tgagagtgaa tcgcaatgca
     5101 ggtaatcatt tcatctgtat atctgtatgc caactggcat tccatctctt ttttcgccga
     5161 tattttgttg tgatcggcga cacttcgctt aaaaaagcac cagtagtggt ttcgcagcca
     5221 tgcggtgtat aaaaaatgat ctcatgcaga tgttttgtga atgtgttggt tgacattcat
     5281 atgaaaaaaa tcataattcc atcatgtttg tgtggggtct tttctgtatc ttacgcatcg
     5341 cactcaagcc tgacagaaaa tatgctgtaa ggctcatatc aaaaaccgcc attagctcat
     5401 caggaagagc agacgacaac caggattgtt gtatggtacg gggttcgagg cctcgatggc
     5461 ggtccaactt ttcaaaactc ttctgaatca gatcccctta ttatcatccc tgcaaagtgg
     5521 aacattgcca ttgtttggct attcaggatg gggcagacca atgaaaaaag cccacacagg
     5581 ggagagtggg ctgaaatggg aagctaaaga ctcaagtaaa cttatcggaa ataaggacca
     5641 cgcattacgg gggctatcat cgccgatggc cgtgattcgg caaatcaggt tgattacgta
     5701 gagagtaaat tatctgctca ccgctgcgtc accccttcgt aaatcaggcg tagcgcgaat
     5761 acaccaataa ttgcaccaat aacccgactg gcaacgcgtt gcatacgccc ataagcacga
     5821 cgcacagcgg gcaaagaaaa cgcctgacta agaaaaactc gccagataat tgatgcgagc
     5881 acaatccccg cccaggccat taaacgtgcc catgttggtg tttcggcatt taatgttact
     5941 gagaaaatac tgataaaaaa taaaacggtt tgcgggttag agagatcggt aattaatccg
     6001 cggcgaaaaa agacatacca gggggcgcta atcggttgtt gtagtgtgct catttgcggt
     6061 gttgactggc ggcgcatgct gcaccacgca aaccataaga gataagcgcc gccgacgatt
     6121 ctgataagcg aaaaaatctc ctcacactgc gtaattagcg ttgcaagacc aaacaaaccc
     6181 aacccggaat aaaatgcatc gcccagcgcc acgcccagcc cggtcagcac ccctgcgcgt
     6241 cgaccggaag ccaggctggt ttgtactacc acaaagagat tggctcccgg attaaaaaaa
     6301 gtaatcacga acagtcctac ggtcaggtaa acggcatgca aaggatccat agtgatttca
     6361 tccataaata agtgaactaa ctgcatcata tttctaccaa aaataatcgg gtgcgagaga
     6421 gatcacaaag tgtcttattt ccggttactg gcgtttatgc cctgactgaa ctaattatta
     6481 atcaacccaa taatgtgggt gggtgatagt gtgataacaa ctctggagcc gtaatatgaa
     6541 aataatctct aaaatgttag tcggtgcgtt agcgttagcc gttaccaatg tctatgccgc
     6601 tgaattgatg accaaagcgg aatttgaaaa agttgaatcg cagtatgaaa aaataggtga
     6661 tatttcaacc agcaatgaaa tgtcgactgc agatgcaaaa gaagatttga tcaaaaaagc
     6721 ggatgaaaaa ggggctgatg tgttggtact gacctccggt caaactgaca ataagatcca
     6781 cggcacggca aatatttata agaagaagta attctgaatc ctatgtaaac atctccgatg
     6841 cgtaagttta tcggtgatca tctattgaaa tttatgccgg ataaagcgtt cgcgctgcat
     6901 tcggcagttc agcttttcag ccgccgccag aacgtcgtcc ggctgatgcc taaataattc
     6961 gccgctgctg ttttatcgcc attaaatttc tccagtgcct gttgtggtgt cagtaagcgt
     7021 ggagcgggag ttttcgccga ctcgcgcgcc agttccggca gtagcagttg cataaactgc
     7081 ggcgttaaat ccggcgtcgg ttccacactt aaaaacagcg ccagtcgttc catcatattg
     7141 cgcagttcac gaatattgcc tggccagtcg tagtgcagca gcacagtttc acttgcctgt
     7201 aacccctggc gtaatgcagc agaaaatggg gcggagagcg ccgccagaga cactttcaaa
     7261 aagctttccg ccagcggaag aatatccgcc acccgctcgc gcagtggtgg caattgcaga
     7321 cgcaaaatac tcagccgata aaacagatca cggcgaaaac gtccttgctg catatcttct
     7381 tccagattgc agtgagtggc gctaatgacc cgtacatcta ccggaacagg ctgatgcccg
     7441 ccgacgcggg tgacctcttt ttcttccagc acccgcagca gccgggtctg caaaggtagc
     7501 ggcatttcgc caatctcatc cagaaacagc gtaccgccgt gggcaatttc gaacagcccg
     7561 gcgcgacctc cgcgtcgcga gccggtaaac gccccttcct catagccaaa cagttctgct
     7621 tccagcagcg attcggcaat cgccccgcag ttgacggcaa caaacggatg cgactttttg
     7681 ccctgtcgcg catcgtggcg ggcaaaatat tcccgatgaa tcgcctgggc cgccagctct
     7741 ttgcccgtcc ctgtttcccc ctcaatcaac accgccgcac tggagcgggc atacagcaaa
     7801 atagtctgcc gtacttgttc catctgtggt gattgaccga gcatatcgcc cagcacgtaa
     7861 cgagtacgca gggcgttgcg ggtggcatcg tgagtgttat ggcgtaacga catgcgcgtc
     7921 atatccagcg catcgctgaa cgcctggcgc acggtggcgg cggaatagat aaaaattccg
     7981 gtcattccgg cttcttctgc caaatcggta atcagccctg cgccgaccac cgcttcggtg
     8041 ccgttagctt ttagctcgtt aatctgcccg cgtgcgtctt cctcggtaat gtagctacgt
     8101 tggtcgaggc gcaaattaaa ggttttttga aacgccacca gcgctggaat ggtttcctga
     8161 taggtgacaa cgccgataga agaggtgagt tttccggctt ttgccagtgc ctgtaacaca
     8221 tcgtagccgc tcggtttaat caaaataact ggcactgaca ggcggctttt caggtacgcg
     8281 ccgttagagc cagccgcgat gatggcgtca cagcgttcgt ttgccagttt cttgcggatg
     8341 taggtcactg ctttttcaaa gccaagctga ataggggtaa tgttcgccag gtgatcaaac
     8401 tcgaggctga tatcgcgaaa cagctcgaac aggcgcgtta cagataccgt ccagataacc
     8461 ggtttgtcgt cattaagccg tggtggatgt gccatagcgc accgcaaagt taagaaaccg
     8521 aatattgggt ttagtcttgt ttcataattg ttgcaatgaa acgcggtgaa acattgcctg
     8581 aaacgttaac tgaaacgcat atttgcggat tagttcatga ctttatctct aacaaattga
     8641 aattaaacat ttaattttat taaggcaatt gtggcacacc ccttgctttg tctttatcaa
     8701 cgcaaataac aagttgataa caaaggatgg gctatgtctc tacactctcc aggtaaagcg
     8761 tttcgcgctg cactgactaa agaaaatcca ttgcagattg ttggcaccat caacgctaat
     8821 catgcgctgt tggcgcagcg tgccggatat caggcaattt atctttctgg cggtggcgtg
     8881 gcggcaggtt cgctggggct gcccgatctc ggtatttcta cccttgatga tgtgctgacc
     8941 gacattcgcc gtatcaccga cgtttgttcg ctgccgctgc tggtggatgc ggatatcggt
     9001 tttggttctt cggcctttaa cgtggcgcgc accgtgaaat tgatgattaa agccggtgcg
     9061 gcaggattgc atattgaaga tcaggttggt gcgaaacgct gcggtcatcg tccgaataaa
     9121 gcgatcgtct cgaaagaaga gatggtggat cggatccgcg cggcggtgga tgcgaaaacc
     9181 gatcctgatt ttgtgatcat ggcgcgcacc gatgctctgg cggtagaggg gctggatgcg
     9241 gcgatcgagc gtgcgcaggc ctatgttgaa gcgggtgccg agatgttgtt cccggaggcg
     9301 attaccgaac tcgccatgta ccgccagttt gccgatgcgg tgcaggtgcc gatcctcgcc
     9361 aacatcaccg aatttggtgc cacgccgctg tttaccaccg acgaattacg cagcgcccat
     9421 gtcgcaatgg cgctgtaccc actttcagcg ttccgcgcca tgaaccgcgc cgctgaacat
     9481 gtctacaacg tcctgcgcca ggaaggcacg cagaaaagcg tcatcgacac catgcagacc
     9541 cgcaacgagc tgtacgaaag catcaactac taccagtacg aagagaagct cgacaacctg
     9601 tttgcccgta gccaggtgaa ataaaaaacg cccgttgatt gtattcgaca gccgatgcct
     9661 gatgcgtcgc tgacgcgact tatcaggcct acgaggtgca ctgaactgta ggtcggataa
     9721 gacggatggc gtcgcatccg acaaccgatg cctgatgcgc cgctgacg
//
LOCUS       DACAOP010000130         9744 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.130, whole genome shotgun sequence.
ACCESSION   DACAOP010000130 DACAOP010000000
VERSION     DACAOP010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9744
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.130"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..750
                     /locus_tag="IT892_003978"
     CDS             <1..750
                     /locus_tag="IT892_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311380.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase"
                     /protein_id="HAP3137124.1"
                     /translation="GAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQE
                     REIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPPLRDRPE
                     DIPLLAKHFTQKMARHMNRAIDAIPTEALRQLMSWDWPGNVRELENVIERAVLLTRGN
                     SLNLHLNVRQSRLLPTLNEDSALRSSMAQLLHPTTPENDEEERQRIVQVLRETNGIVA
                     GPRGAATRLGMKRTTLLSRMQRLGISVREVL"
     gene            772..1620
                     /locus_tag="IT892_003979"
     CDS             772..1620
                     /locus_tag="IT892_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter"
                     /protein_id="HAP3137125.1"
                     /translation="MRNKLSFDLQLSARKAAIAERIAAHKIARSKVSVFLMAMSAGVF
                     MAIGFTFYLTVIADAPSSQALTHLVGGLCFTLGFILLAVCGTSLFTSSVMTVMAKSRG
                     VISWRTWLINALLVACGNLAGIACFSLLIWFSGLVMSENAMWGVAVLHCAEGKMHHTF
                     TESVSLGIMCNLMVCLALWVSYCGRSLCDKIVAMILPITLFVASGFEHCIANLFVIPF
                     AIAIRHFAPTSFWQLAHSSADHFPVLTISHFITANLLPVMLGNIIGGAVLVSICYRAI
                     YLRQEP"
     gene            complement(1657..2718)
                     /locus_tag="IT892_003980"
     CDS             complement(1657..2718)
                     /locus_tag="IT892_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP3137126.1"
                     /translation="MLEMLMQWYRRRFSDPEAIALLVILVAGFGIIFFFSGLLAPLLV
                     AIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGILLLMAFVVLPIAWQQGIYLIRD
                     MPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLL
                     TIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVL
                     EMIVVGIATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVIGVALFQFGAGT
                     EFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPL
                     ATLIKAVIHAWPDGQIAQE"
     gene            2931..4394
                     /gene="bepA"
                     /locus_tag="IT892_003981"
     CDS             2931..4394
                     /gene="bepA"
                     /locus_tag="IT892_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-barrel assembly-enhancing protease"
                     /protein_id="HAP3137127.1"
                     /translation="MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTL
                     SIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINND
                     EINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLT
                     WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFD
                     PQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYL
                     AKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQP
                     LLAAEPGNAWYLDLATDIDLGQNKANDAINRLKNARDLRTNPVLQLNLANAYLQGGQP
                     QEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLL
                     SSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM"
     gene            4415..4774
                     /gene="arsC"
                     /locus_tag="IT892_003982"
     CDS             4415..4774
                     /gene="arsC"
                     /locus_tag="IT892_003982"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311384.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HAP3137128.1"
                     /translation="MTKQVKIYHNPRCSKSRETLNLLKENGVEPEVVLYLETPADAAT
                     LRDLLKMLGMNSARELMRQKEDLYKELNLADSSLSEEALIQAMVDNPKLMERPIVVAN
                     GKARIGRPPEQVLEIVG"
     gene            complement(4880..5626)
                     /gene="hda"
                     /locus_tag="IT892_003983"
     CDS             complement(4880..5626)
                     /gene="hda"
                     /locus_tag="IT892_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA inactivator Hda"
                     /protein_id="HAP3137129.1"
                     /translation="MVNFSRFCEILVEVSLNTPAQLSLPLYLPDDETFASFWPGDNSS
                     LLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVP
                     EVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNL
                     GLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRT
                     LFMTLDQLDRASITAQRKLTIPFVKEILKL"
     gene            complement(5676..6965)
                     /gene="uraA"
                     /locus_tag="IT892_003984"
     CDS             complement(5676..6965)
                     /gene="uraA"
                     /locus_tag="IT892_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAP3137130.1"
                     /translation="MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPA
                     TVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
                     LVSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKTII
                     ISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTL
                     YTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVI
                     SGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVM
                     GGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGM
                     ALATIVGIGLSLIFKMISVLRPEEVVLDAEDADITDK"
     gene            complement(7051..7677)
                     /gene="upp"
                     /locus_tag="IT892_003985"
     CDS             complement(7051..7677)
                     /gene="upp"
                     /locus_tag="IT892_003985"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAP3137131.1"
                     /translation="MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEAT
                     ADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMY
                     RNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
                     AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK"
     gene            8002..9039
                     /gene="purM"
                     /locus_tag="IT892_003986"
     CDS             8002..9039
                     /gene="purM"
                     /locus_tag="IT892_003986"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAP3137132.1"
                     /translation="MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGG
                     FGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEP
                     LFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFC
                     VGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPL
                     ADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQW
                     PEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIK
                     ASDSEQRVVIE"
     gene            9039..9677
                     /gene="purN"
                     /locus_tag="IT892_003987"
     CDS             9039..9677
                     /gene="purN"
                     /locus_tag="IT892_003987"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAP3137133.1"
                     /translation="MNIVVLISGNGSNLQAIIDACKTNKIKGTARAVFSNKADAFGLE
                     RARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAG
                     RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD
                     TEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE"
BASE COUNT         2440 a         2552 c         2535 g         2217 t
ORIGIN      
        1 ggggcattta ctggtgcgat taatacccat cgtggtcgtt ttgaaattgc cgatggcggc
       61 acgttgtttc tcgatgaaat tggcgatctg ccgttagaac ttcagcctaa actgctgcgc
      121 gtattgcagg aacgggagat tgagcgtctc ggcgggagta gaacgatccc ggtaaatgtc
      181 agagtcattg ccgccaccaa ccgtgatttg tggcaaatgg ttgaagatcg ccagtttcgc
      241 agcgatctct tttatcgcct gaatgtcttc ccactggaac tgccgccact gcgcgaccgt
      301 ccggaagata tccctctttt agcaaagcat ttcacgcaaa aaatggcgcg ccatatgaat
      361 cgcgcaattg acgccatccc gaccgaggcg ctacgccagt tgatgtcgtg ggactggccg
      421 ggcaacgtgc gcgagctgga aaacgtgatt gagcgagcgg tactactgac tcgcggtaac
      481 agtctgaatt tacatcttaa tgtccgacaa agccgtttac tgccgacgct aaatgaagat
      541 tcagcgcttc gcagttcaat ggcgcagttg ctgcacccga cgacgccaga gaatgacgaa
      601 gaagaacgtc agcgcattgt tcaggtattg cgagaaacca atggcattgt tgccgggccc
      661 cgtggcgcgg cgacgcgatt agggatgaag cgcaccacgc tgctgtcacg aatgcagcgg
      721 ctggggatct cggttcgcga ggtgttgtaa tctgtttttg caggagtatg catgagaaac
      781 aaactctctt tcgacttgca gttgagcgcc agaaaagcgg caatcgctga acggattgcc
      841 gcccataaaa ttgcccgcag taaagtgtcg gtctttttaa tggcgatgtc cgctggcgtg
      901 tttatggcga tcggatttac tttttacctt accgttatcg ccgatgcccc gtcttcacag
      961 gcattaaccc atctggtggg cggcctttgc tttacacttg gctttatttt gctggcggtt
     1021 tgcggcacca gcctgttcac ctcgtcggta atgacggtaa tggcaaaaag tcggggcgtt
     1081 attagttggc gaacatggct gattaatgca cttctggtgg cctgcggtaa tctggcaggt
     1141 attgcctgtt tcagtttgtt aatctggttt tccgggctgg tgatgagtga aaacgcgatg
     1201 tggggagtcg cggttttaca ctgcgccgag ggcaaaatgc atcatacatt tactgaatca
     1261 gtcagcctcg gcattatgtg caatctgatg gtttgcctgg cgctgtgggt gagttattgc
     1321 ggacgttcgt tatgcgacaa aatcgtcgcc atgattttgc ccatcaccct gtttgtcgcc
     1381 agtggttttg agcactgtat cgccaatttg tttgtgattc cgttcgccat tgccattcgc
     1441 catttcgccc ctacctcctt ctggcaactg gcgcacagta gcgcagacca ttttccggta
     1501 ctgacgatca gccattttat taccgccaat ctgctcccgg tgatgctggg taatattatc
     1561 ggcggtgcag tgctggtgag tatttgttat cgggctattt atttacgtca ggaaccctaa
     1621 aaatcagccc ggcgaaacag ttcgtcgggc tgaagattat tcttgcgcga tttgcccatc
     1681 gggccaggcg tgaatcacgg ctttgatcag cgtcgccaat ggaatggcga agaatacgcc
     1741 ccagaatccc cacaaaccac cgaagatcac caccgataaa ataatcacca gcggatgcag
     1801 gttaaccgct tcggagaaca acaccggcac tagcaggttg ccgtccagcg cctgaataat
     1861 cagatacacc gcgaagcagc tccagaattc cgtgccagca ccaaactgga atagcgccac
     1921 gccaatcacc ggaatggtca ccacaaatgc gccaatgtac ggaataagaa ccgagaagcc
     1981 gaccagcacc gccagcagca gcgaatagtt cagcccgaag agtaagaacc ccagccaggt
     2041 ggcgatcccc accacgatca tctccagcac tttgccgcgg atatagttgg tgatttgttg
     2101 attcatctcc ttccacacct gtcctgccag tccgcggtta cgcggtagca cccgacgaac
     2161 ggcgttcagc atctgctctt tgtctttcaa caggaagaag accatcaatg gcaccagcac
     2221 cagatagaca gctatggtga gcaaaccgac cagcgaggcg agggaaattt tcaccaccga
     2281 atcgcccatg gtaagcatcc gactgcgcat attttcggcc attgcatcaa taatgcccgc
     2341 atccatcaac gccggatagc ggcgcggcaa cgtggcggca aagtcagaaa gcttattgag
     2401 catccccggc atatcgcgga ttaagtagat gccctgttgc caggcgatag gcagtaccac
     2461 gaacgccatc agtagcaata taccgacgaa aaccaccaat acaatcgacg tcgcccagcg
     2521 gcgggagcag ccaatagatt gcaggcgcac ggttggccat tccagcaaat aggccagcac
     2581 aatagccacc agcaacggag caagcaggcc actaaagaaa aagataatgc caaatccggc
     2641 aactaaaata accagcaagg caatcgcttc cgggtcgcta aaacggcggc gataccattg
     2701 catcaacatt tcgagcataa agaccttccc tgaacctcaa gagcgggatt gcgatccgca
     2761 attgtatcga aatgtcacaa aaaagacttc gctttttatg acggattcag gaaactgaaa
     2821 agtcatttga gtgggctaat cttcgccgtt acactcaaag gcggcgcggt gggaacgata
     2881 tttcacagta tcggtcaaat gactatcttc agaaatacag gatagaggtt atgttcaggc
     2941 agttgaaaaa aaacctggtt gcaaccctca ttgctgctat gaccattggt caggtagccc
     3001 cggcgtttgc cgacagcgca gacaccttgc cggatatggg aacctccgca ggaagcacgc
     3061 tttccattgg ccaggaaatg cagatgggcg actattatgt ccgccagcta cgcggcagcg
     3121 cgccgttaat taatgacccg ctgttaacgc aatatattaa ttcgctgggt atgcgtctgg
     3181 tttcgcatgc caattcggtt aagacaccgt ttcatttctt tctgatcaac aacgacgaaa
     3241 ttaacgcctt tgctttcttt ggcggcaacg tggtgctgca ctctgccctg ttccgttatt
     3301 ccgataacga aagtcaactg gcttcagtta tggcgcacga aatctcccac gtcacccaac
     3361 gtcacctggc gcgagcgatg gaagatcagc agcgcagcgc gccgctgacc tgggtcggcg
     3421 cattaggttc tattttactg gcgatggcca gtccgcaggc ggggatggct gcgctgaccg
     3481 gtacactggc gggaacgcgc caagggatga tcagtttcac ccagcaaaat gaacaggaag
     3541 cggaccgcat tggtattcag gtgctgcaac gctcgggatt cgatccgcag gcgatgccga
     3601 ccttcctcga aaaattgctc gatcaggcgc gttactcctc gcgtccgccg gaaattttat
     3661 tgactcaccc gttgccggaa agtcgtctgg cagatgcccg caaccgtgct aatcagatgc
     3721 gtccgatggt ggtgcagtcg tcggaagatt tctatctggc gaaagcgcgc acactgggga
     3781 tgtataattc cggacgtaac cagctcacca gtgatttgct ggatgaatgg gcgaaaggaa
     3841 acgttcgtca gcaacgagcg gcgcaatatg gtcgtgcttt acaggcgatg gaagccaata
     3901 aatacgacga agcgcgtaaa acgctgcaac cgttactggc ggcagaacct ggcaacgcat
     3961 ggtatctcga tctggctacc gatatcgatc ttgggcaaaa caaagccaat gacgctatca
     4021 atcgcctgaa aaatgcccgc gatttgcgca ccaatccagt gttgcagctc aacctggcga
     4081 acgcttatct gcaaggcggt caaccacaag aagcggccaa tattctgaat cgctacactt
     4141 ttaacaataa agatgacagc aacggctggg atttactggc acaggcggaa gccgcgctaa
     4201 ataaccgcga tcaggaactg gctgcgcgag cagaaggtta tgcgctcgcc gggcgactcg
     4261 atcaggccat ttccttgttg agtagcgcca gttctcaggt gaaattaggc agcctgcaac
     4321 aagcgcgtta cgatgcgcgc atcgaccagt tgcgccagct gcaggaacgc tttaagcctt
     4381 ataccaagat gtaattcgca ttaaaggaag aacaatgacc aaacaggtaa aaatctacca
     4441 taacccacgc tgttcaaaga gccgggaaac gctaaacctg ctgaaagaaa acggcgtgga
     4501 gccagaagtg gtgctctacc ttgagacacc cgccgatgcg gcaacgctgc gtgatttgct
     4561 gaaaatgctg gggatgaata gcgctcgtga attgatgcgc cagaaagagg atctttataa
     4621 agaactgaac ctggctgaca gttcgcttag cgaagaggcg ctgattcagg caatggtgga
     4681 taatccgaag ctaatggagc gcccgattgt ggtcgcgaat ggcaaagcgc gaattggtcg
     4741 tccaccggag caggtgctgg aaatcgtggg ttaagaagtg ctccatcgct agttgaagca
     4801 cattgccgga tgcgacgctt gccgcgtctt atccggccga cgaatactat gggtgcgcat
     4861 ccgacaataa acgtcttgtc tacagtttca gaatttcttt cacaaacgga atggtcagct
     4921 tacgttgcgc ggtaatcgac gcacgatcca actgatccaa cgtcataaat aacgtgcgca
     4981 tctctctgtc gagccgcttc aacaagaaac gccccacatc ttccggcagt tcaaaaccac
     5041 gcaaacgcgc gcgtaactgt agcgcctgca acttatcttc atcagaaagt ggctgcaatt
     5101 tgtagatctg cccccagtcg agacgcgacg cgagatccgg taatcccaga ttcaactgcc
     5161 gcggtggacg atcgccggtg attaacaacc gtgttttgcc cgattccaga attcgattgt
     5221 agagatcgaa aatcgccatc tcccacaact catcgcctgc aatacactca atgttgtcga
     5281 tacagaccag cgacaaatgc tccataccgt cgagcacttc cggaacaaac caggtgcgtt
     5341 tatccagcgg gacatagccc accgcatcgc cacgctgcga caattccgcg caagccgcgt
     5401 gcagcagatg gctgcgcccc gcgccttcgc gtgcccagag atagatgtaa ccgctatgtt
     5461 cctgacgcag cacgttttgc agcgcggcca gtaaagagga gttatccccc ggccagaaac
     5521 ttgcaaaggt ttcgtcgtca ggaagataaa gtggcaaaga gagctgtgcc ggtgtgttca
     5581 gagatacctc aaccaggatt tcacaaaatc gcgagaagtt taccacagaa tcccatgatg
     5641 tttgaaccgg gcagcaacac tgcccggtcg gtacattatt tgtctgttat atccgcgtct
     5701 tctgcgtcca gcaccacttc ttcagggcgc agcacactaa tcattttgaa gatcaaactt
     5761 aagccgatac cgacgatggt cgccagcgcc atacctttca gctccgccgc gccgatgttt
     5821 accttcgcgc cactgacacc gatgatcaaa atcacggaag tcaggatcag gttctgtgct
     5881 ttgttgtaat ccactttcga ttcgatcaaa acacgaatac cggaagcacc gatgacacca
     5941 taaagcagca gcgaaacgcc gcccatcacc ggcaatggga tcatctggat agcagcagcc
     6001 agtttaccga cgcaggaaag caggatagcg aaaatcgccg ccccgccgat aacccaggta
     6061 ctgtaaacac gggtgatcgc catcacgcca atgttttccc cgtaggtggt gtttggcgtg
     6121 gagccaaaga agccggagat cacggtcgac aagccgttag caaacatcga acggtgcaga
     6181 cctggatcgc gcagcagatc ttttttgacg atattagccg ttaccaccag gtgccctacg
     6241 tgttcggcaa taaccactaa cgccgctggc agaatagtca gaatggcaaa ccactcgaag
     6301 cgcggcgtat agagggttgg cagcgcaaac cagtgagcat taataatcgg cgtggtatcg
     6361 acaattccca ttgcgaaaga gagcgcgtaa cccaccagca cgccaattaa aatcgggata
     6421 attgccagga aaccacgaaa cagcacggaa cctaaaaccg tgactgccag ggtggtaatg
     6481 gagatgatga tggttttgga gtctggcgtt tgcccttcag ccgggagtaa acctgccata
     6541 ccggcagcta cgcccgccag ctccagaccg atgacggcaa cgattgcgcc cattgccgca
     6601 ggtggaaaca gcacgtccag ccagccggtc cccgctttct tcacgataaa agaaaccagg
     6661 cagaacagca cgccgcacat aataaagccg cccagcgcga cttcataccc taacggcaac
     6721 agtaacaata ccggtgaaat aaaggcaaag ctggaaccaa gataagccgg aattttccct
     6781 ttacagatga agagatacag cagtgttcct ataccgttaa ataacagtac agtcgccggg
     6841 ttaatatgaa ataagacggg caccaggacg gttgcaccaa acatggcgaa caaatgttgc
     6901 aaactaagcg ggattgtctg taaaagtggc ggtctttcac tcaccccgat agcacggcgc
     6961 gtcatagtat tatcctctgt attatgtgtt ataggcgctt tactcaaaaa aaagccgact
     7021 cttaaagtcg gctttaatta tttttattct ttatttcgta ccaaagattt tgtcaccggc
     7081 atcgccgagg cccggaataa tgtatccgtg ctcgttcagt ccctggtcaa tcgatgcagt
     7141 atacagttcg acgtccgggt gcgctttttc cagcgctgcg ataccttctg gcgcagcgac
     7201 cagcaccaga actttgatgc tgctgcagcc cgcttttttc agcaggtcga tggtcgcgat
     7261 aacggaacca ccggttgcca gcattgggtc aacgatcagc gccatacgct catcgatgtt
     7321 agaaaccagt ttctggaagt acggtaccgg ctccagcgtt tcttcattac ggtacatacc
     7381 gacgacgctg atgcgcgcgc tcggaacgtt ttccagcaca ccgtccatca tccccagacc
     7441 cgcacgcaga attggcacaa cggtaatttt cttacctttg atctggtcga tttctaccgg
     7501 gccgttccag ccttcgatag ttactttttc cgtttcgagg tcggcggtcg cttcgtaagt
     7561 cagcaggcta cccacttcgg aagcgagttc gcgaaagcgc ttggtgctga tatcttgctc
     7621 acgcatcagt cccagcttgt gtttgacgag tgggtgtttg acttccacga tcttcatact
     7681 ctttctcctt tgaggggcag ccacaaaaaa aatcgacgga ttatacctcc tttcttcaag
     7741 gcggcaatat tattttcgtt gactttagtc aaaatgataa cggtttgaga taaagttatt
     7801 ttatattcaa atggttatgg aagaagatta ttccatccga aaacgatcct ttgccctggt
     7861 acaagtattg ttttgccgcg cgcctgggga aaagacgtac aaaaaggttg tgtaaagcag
     7921 tctcgcaaac gtttgctttc cctgttagaa ttgcgccgaa ttttattttt ctaccgcaag
     7981 taacgcgtgg ggacccaagc agtgaccgat aaaacctctc ttagctacaa agatgccggt
     8041 gttgatattg acgcgggtaa tgctctggtt ggaagaatca aaggcgtagt gaagaaaacg
     8101 cgtcgtccgg aagtgatggg cggtctgggc ggcttcggtg cgctgtgtgc attgccgcaa
     8161 aaatatcgtg aacccgtgct ggtttccggc actgacggcg taggtaccaa gctgcgtctg
     8221 gcgatggact taaaacgtca cgacaccatt ggtattgatc tggtcgccat gtgcgttaat
     8281 gacctggtgg tgcaaggtgc ggaaccgctg tttttcctcg actattacgc aaccggaaaa
     8341 ctggatgtgg ataccgcttc agcggtgatc agtggcattg cggaaggttg tctgcaatcg
     8401 ggctgttcac tggtgggtgg cgaaacggca gaaatgccgg ggatgtatca cggtgaagat
     8461 tacgatgtcg ctggtttctg cgttggcgtg gtagaaaaat cagaaatcat cgacggctct
     8521 aaagtcagcg atggcgatgt gctgattgca ctcggctcca gcggtccgca ctcgaacggc
     8581 tattcgctgg tgcgcaaaat tcttgaagtc agcggttgtg atccgcaaac caccgaactt
     8641 gatggtaagc cattagccga tcatctgctg gcaccgaccc gcatttacgt gaagtccgtg
     8701 ctggagttga ttgaaaaggt cgatgtgcat gctattgcgc acctgaccgg cggcggcttc
     8761 tgggaaaaca ttccgcgcgt attgccagat aatactcagg cagtgattga tgaatcatcc
     8821 tggcagtggc cggaagtgtt caactggctg caaacggcag gtaacgttga gcgccatgaa
     8881 atgtatcgca ccttcaactg cggcgtcggg atgattattg ccctgcctgc tccggaagtg
     8941 gacaaagccc tcgccctgct caatgccaac ggtgaaaacg cgtggaaaat cggtatcatc
     9001 aaagcctctg attccgaaca acgcgtggtt atcgaataat gaatattgtg gtgcttattt
     9061 ccggcaacgg aagtaatttg caggcaatta ttgacgcctg caaaaccaac aaaattaaag
     9121 gcaccgcacg ggcagttttc agcaataagg ccgacgcgtt cggccttgaa cgcgcccgcc
     9181 aggcgggtat tgcaacgcat acgctcatcg ccagcgcgtt tgacagtcgt gaagcctatg
     9241 accgggagtt gattcatgaa atcgacatgt acgcacccga tgtggtcgtg ctggctggtt
     9301 ttatgcgcat tctcagcccg gcgtttgtct cccactatgc cgggcgtttg ctgaacattc
     9361 acccttctct gctgccgaaa tatcccggat tacacaccca tcgtcaggcg ctggaaaatg
     9421 gcgatgaaga gcacggtaca tcggtgcatt tcgtcaccga tgaactggac ggtggcccgg
     9481 ttattttaca ggcgaaagtc ccggtatttg ctggtgatac ggaggatgac atcaccgccc
     9541 gcgtgcaaac ccaggaacac gctatttatc cactggtgat tagctggttt gccgatggtc
     9601 gtctgaaaat gcacgaaaac gccgcgtggc tggatggtca acgtctgccg ccgcagggct
     9661 acgctgccga cgagtaatgc cccgtagtta aagcgccagc tctgccgctg gcgtttttca
     9721 attcacctgt aaatcgcaag ctcc
//
LOCUS       DACAOP010000131         9675 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.131, whole genome shotgun sequence.
ACCESSION   DACAOP010000131 DACAOP010000000
VERSION     DACAOP010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9675
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.131"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..414)
                     /locus_tag="IT892_003988"
     CDS             complement(<1..414)
                     /locus_tag="IT892_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3137134.1"
                     /translation="MNTQYNSSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVA
                     PQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGS
                     AWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGI"
     gene            complement(786..1676)
                     /gene="malG"
                     /locus_tag="IT892_003989"
     CDS             complement(786..1676)
                     /gene="malG"
                     /locus_tag="IT892_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001252048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalG"
                     /protein_id="HAP3137135.1"
                     /translation="MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNF
                     ATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVAL
                     STTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
                     GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVV
                     FILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITI
                     VFLLAQRWLVNGLTAGGVKG"
     gene            complement(1691..3235)
                     /gene="malF"
                     /locus_tag="IT892_003990"
     CDS             complement(1691..3235)
                     /gene="malF"
                     /locus_tag="IT892_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalF"
                     /protein_id="HAP3137136.1"
                     /translation="MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAI
                     TTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTF
                     ERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
                     ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGT
                     LTNNQSGVKYRPNNQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKP
                     FLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISIL
                     IFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLL
                     KAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNG
                     GPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKA
                     TRMKFD"
     gene            complement(3389..4579)
                     /gene="malE"
                     /locus_tag="IT892_003991"
     CDS             complement(3389..4579)
                     /gene="malE"
                     /locus_tag="IT892_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate-binding protein MalE"
                     /protein_id="HAP3137137.1"
                     /translation="MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYN
                     GLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL
                     AEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPA
                     LDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGL
                     TFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
                     KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYE
                     EELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQT
                     RITK"
     gene            4944..6059
                     /gene="malK"
                     /locus_tag="IT892_003992"
     CDS             4944..6059
                     /gene="malK"
                     /locus_tag="IT892_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011915502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter ATP-binding
                     protein MalK"
                     /protein_id="HAP3137138.1"
                     /translation="MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKST
                     LLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKL
                     AGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP
                     LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP
                     LELYHYPADRFVAGFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQ
                     VGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDV
                     VLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV"
     gene            6131..7471
                     /gene="lamB"
                     /locus_tag="IT892_003993"
     CDS             6131..7471
                     /gene="lamB"
                     /locus_tag="IT892_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin LamB"
                     /protein_id="HAP3137139.1"
                     /translation="MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGE
                     QQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEAT
                     DPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVG
                     FGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDY
                     GRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSG
                     VAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVG
                     IRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFA
                     TYAKWDEKWGYDYTGNADNNANFGKAVPADFNGGSFGRGDSDEWTFGAQMEIWW"
     gene            7714..8634
                     /gene="malM"
                     /locus_tag="IT892_003994"
     CDS             7714..8634
                     /gene="malM"
                     /locus_tag="IT892_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon protein MalM"
                     /protein_id="HAP3137140.1"
                     /translation="MKMNKSLIVLCLSAGLLASAPGISLADVNYVPQNTSDAPAIPSA
                     ALQQLTWTPVDQSKTQTTQLATGGQQLNVPGISGPVAAYSVPANIGELTLTLTSEVNK
                     QTSVFAPNVLILDQNMTPSAFFPSSYFTYQEPGVMSADRLEGVMRLTPALGQQKLYVL
                     VFTTEKDLQQTTQLLDPAKAYAKGVGNSIPDIPDPVARHTTDGLLKLKVKTNSSSSVL
                     VGPLFGSSAPAPVTVGNTAAPAVAAPAPAPVKKSEPMLNDTESYFNTAIKNAVAKGDV
                     DKALKLLDEAERLGSTSARSTFISSVKGKG"
     gene            9060..9675
                     /locus_tag="IT892_003995"
                     /pseudo
     CDS             9060..9675
                     /locus_tag="IT892_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005136105.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SopA family protein"
BASE COUNT         2508 a         2395 c         2424 g         2348 t
ORIGIN      
        1 aataccgcca ataatgcgat aaataacaaa ttccgggaca taacctgcca gataaacagg
       61 cacagtgttg tccgggttta tagaggtaaa accaagttct ggccaggcag aacctacacc
      121 agaaataaaa aacaggacag cagcaatctt aagtgaatca cgacgaccga agcggttact
      181 gcaataacca ccgagggcac cgccgatgat gcaaccaatc agagcgctgg ccacgcaaaa
      241 ccctaacagg gagttggcag cggattcact taagttttgt ggagcaacaa agacggtatt
      301 gagtgactca acagtaccgg aaataacggc ggtgtcgtag ccaaataata aaccacctaa
      361 tgtagcgact aaggtaatcg aaaatatata actggaatta tactgggtat tcattcagac
      421 ctgccttaga ccattctgat cttttatcag tgcattgatg ttggaattgt caggcagtta
      481 aggcaattat cattttttac aatgcgttta cgtaatgtct tttctgtgat cttaattgtg
      541 ataattatcc aaaattgata aaaacaatac tattgccgtg actcagagca cgaaagagaa
      601 ttatcgtaag tgggaaaaca aataacgtaa aaataataag ctctatgatg gaaatattaa
      661 ccggcgaacg attcagattg cagacgaaag aaaaaaaggc gctccgtgga gcgccgaata
      721 acagtcacaa gttgggataa cgtaagttga gggtgcagcg gcataacatt ggcagaacaa
      781 catctttaac ctttcacacc acctgccgtc aggccgttga ccagccagcg ttgagccagc
      841 aagaagacga tggtgatcgg taatgcagac atcacggcag cggcggcaaa gtcaccccac
      901 aggtagtttt gcgggttgag gtattgctgc atccccacgg ccagggtgta gctgtttacg
      961 tcacgcagta acagcgacgc gaccggaact tcagtaatgg cagcgataaa cgacaggatg
     1021 aataccaccg ccagaatcgg tactgacagc ggcaacagga caaggcggaa ggcctgccac
     1081 ggtgtcgcac catccagcgc agcagcttct tccagcgaac tgtcgatggt ttcgaaatag
     1141 cctttgatgg tccagacatg cagcgcaatc ccacccagat acgcgaaaat tacgccgccg
     1201 tgagtattca ggccaatgaa tggaatgtac tcacccagac gatcaaacaa cgcatacaac
     1261 gcgaccagtg aaagtactgc cgggaacatc tggaaaatca gcattccttt cagcagcgtc
     1321 gctttgcctg gaaagcgcat acgggcgaaa gcgtaggcgc aggtggtgga gagcgccaca
     1381 atgccaatcg cggaaatccc ggcgaccttt accgagttcc acagccacag cagtaccggg
     1441 aatggcggtg gcgtaatgcg accatcagcc tgttcaacgc taaaacctaa cgccagtttc
     1501 cagtgatccc aggagatttg ctccgggatc aggctgccgg tcgcaaagtt tccctgacgc
     1561 agcgagatag cgacgaccat cagcagcggg aacataatcg ctgcgataaa aagtagcagt
     1621 agcaggtgag taataaataa acgagctttt tgcgatttcg gttggaccat tgccattttt
     1681 gttatctccc ttaatcaaac ttcattcgcg tggctttcag gttcactatc gccagcgcac
     1741 ccaccagcag gaagatcagc gtggcaattg ctgccgccag accgaagtcc tgacccccgc
     1801 cgccttcaaa agcgatgcgg taggtgtagt taacaagcag gtcggtataa ccggctggcg
     1861 tggtcgtgcc aagacgatcc gggccgccgt tggttaacag ttgaatcagc acgaagttgt
     1921 taaagttaaa ggcgaagctg gcgatcatca gcggcgtcag cggtttaatc agcagcggca
     1981 gcgtaatctt aaagaagttc tggaacggac ctgcgccatc cattgctgag gcttcataca
     2041 aatcgtccgg aatcgctttc agcaagccca tgcagaggat catcatgtac ggataaccca
     2101 gccaggtatt gacgataatt agcatcgtgc gggcggtggt cggatcgctg aaccaggcgg
     2161 gcttcacgcc aaacagcgcg ctcaacatca tgttgatttc accgaagctc tggttaaaca
     2221 accctttgaa aatcaagatt gaaatgaacg atggcaccgc gtagggcaga atcagcagga
     2281 cgcgatagac cgctttgccg cgcaacgctt cccactgcac cagacacgcc agaaccatgc
     2341 cgaccgccac cgttaaaaag acagtgatca gcgagaacac cacggtccag acgaaaatgg
     2401 cgaggaacgg tttctgaatg ccttcgtcgg taaagacgcg ggtaaagttt ttccagccgg
     2461 tggtcacggt gtaaccgggg cttagctttt catcacccca gttgccgtcg gcggtaatgg
     2521 actggtaaaa gccaatttgg ttattcggac gatatttcac gccgctctga ttattcgtca
     2581 acgtgccgtc accgtcgagt gtgtagagcg gctgcgtgcc agaaaactgg cgcagggagc
     2641 tcatcatcac tttgttgcca tccggcagaa tggcggtaat gtcactcagc gcctgacgat
     2701 tctgggtaat cacgcgcaga ttcgcgcgtt cgccttcggg ctgggcggtc gtttctttca
     2761 gttgcagttt ttgctcgccg ccaaatttaa aagcgtcgga gaggtaattt ttgccggttt
     2821 cgccgtcgct gagcgccagt tgccactcat cgcccgccgg gtaaagacca aagttatagg
     2881 ttttgcctgc ttgccaggag cgatctaaca acacttcctg cgcacgttca aaagtcagct
     2941 ggttagtgct gctgtagttg gtgaaggcaa tggcgatggt gcagaccaga gggaagagga
     3001 cgaataatcc cattccagcc attcccgggt aaacatagcg ccaggcgtag gctttacgat
     3061 tggcgaaaat atacagcccc gctgaactca atatcagcgt ggtaatggcg aacaggtatt
     3121 ccccttgtgc gtacattaaa acaacaaggt aacccaccag caggccgagc agacctagca
     3181 ctgaccattt cagcgcgtcg ctttgccacc aatgtttctt tttaatgaca tccatggggt
     3241 tcttcctcat tccaggacgg ataaggcttt cacgccttat ccgacaacaa ctgcctgatg
     3301 cgacgctgac gcgtcttatc aggcctacat acgtttcggt tttgtaggcc ggacaaggcg
     3361 ttcacgccgc atccggcatt tcacagcatt acttggtgat acgagtctgc gcgtctttca
     3421 gggcttcatc gacagtctga cgaccgctgg cggcgttgat caccgcagta cgcacggcat
     3481 accagaaagc ggacatctgc gggatgttcg gcatgatttc acctttctgg gcgttttcca
     3541 tggtggcggc aatacgtgga tctttcgcca actcttcctc gtaagacttc agcgctacgg
     3601 cacccagcgg tttgtcttta ttaaccgctt ccagaccttc atcagtcagc agatagtttt
     3661 cgaggaactc tttcgccagc tctttgttcg gactggcggc gttaatacct gcgctcagca
     3721 cgccaacgaa cggtttggat ggttgaccct tgaaggtcgg cagtaccgtt acaccataat
     3781 tcactttgct ggtgtcgatg ttggaccatg cccacgggcc gttgatggtc atcgctgttt
     3841 cgcctttatt aaaggcagct tctgcgatgg agtaatcggt gtctgcattc atgtgtttgt
     3901 ttttaatcag gtcaaccagg aaggtcagac ccgctttcgc gccagcgtta tccacgccca
     3961 cgtctttaat gtcgtacttg ccgttttcat acttgaacgc ataacccccg tcagcagcaa
     4021 tcagcggcca ggtgaagtac ggttcttgca ggttgaacat cagcgcgctc ttacctttcg
     4081 ctttcagttc tttatccagc gccgggatct cttcccaggt ttttggcggg ttcggcagca
     4141 gatctttgtt ataaatcagc gataacgctt caacagcgat cgggtaagca atcagcttgc
     4201 cgttgtaacg tacggcatcc caggtaaacg gatacagctt gtcctggaac gctttgtccg
     4261 gggtgatttc agccaacagg ccagattgag cgtagccacc aaagcggtcg tgtgcccaga
     4321 agataatgtc agggccatcg ccagttgccg caacctgtgg gaatttctct tccagtttat
     4381 ccggatgctc aacggtgact ttaattccgg tatctttctc gaatttctta ccgacttcag
     4441 cgagaccgtt atagccttta tcgccgttaa tccagattac cagtttacct tcttcgattt
     4501 tggcgagagc cgaggcggaa aacatcatcg tcgttaatgc ggataatgcg aggatgcgtg
     4561 cacctgtttt tattttcata atctatggtc cttgttggtg aagtgctcgt gaaaacacct
     4621 aaacggactc tagtttcttt atacggcaac ctctttccat cctccttgcc cctacgcccc
     4681 accgtcgctt tgtgtgatct ctgttacaga attggcggta atgtggagat gcgcacataa
     4741 aatcgccacg atttttgcaa gcaacatcac gaaattcctt acatgacctc ggtttagttc
     4801 acagaagccg tgttctcatc ctcccgcctc ctcccccata aaaaagccag ggggtggagg
     4861 atttaagcca tctcctgatg acgcatagtc agcccatcat gaatgttgct gtcgatgaca
     4921 ggttgttaca aagggagaag ggcatggcga gcgtacagct gcaaaatgta acgaaagcct
     4981 ggggcgaggt cgtggtatcg aaagatatca atctcgatat ccatgaaggt gaattcgtgg
     5041 tgtttgtcgg accgtctggc tgcggtaaat cgactttact gcgcatgatt gccgggcttg
     5101 agacgatcac cagcggcgac ctgttcatcg gtgagaaacg gatgaatgac actccgccag
     5161 cagaacgcgg cgttggtatg gtgtttcagt cttacgcgct ctatccccac ctgtcagtag
     5221 cagaaaacat gtcatttggc ctgaaactgg ctggcgcaaa aaaagaggtg attaaccaac
     5281 gcgttaacca ggtggcggaa gtgctacaac tggcgcattt gctggatcgc aaaccgaaag
     5341 cgctctccgg tggtcagcgt cagcgtgtgg cgattggccg tacgctggtg gccgagccaa
     5401 gcgtattttt gctcgatgaa ccgctctcca acctcgatgc tgcactgcgt gtgcaaatgc
     5461 gtatcgaaat ctcccgtctg cataaacgcc tgggccgcac aatgatttac gtcacccacg
     5521 atcaggtcga agcgatgacg ctggccgaca aaatcgtggt gctggacgcc ggtcgcgtgg
     5581 cgcaggttgg gaaaccgctg gagctgtacc actatccggc agaccgtttt gtcgccggat
     5641 ttatcggttc gccaaagatg aacttcctgc cggtaaaagt gaccgccacc gcaatcgatc
     5701 aagtgcaggt ggagctgccg atgccaaatc gtcagcaagt ctggctgcca gttgaaagcc
     5761 gtgatgtcca ggttggagcc aatatgtcgc tgggtattcg cccggaacat ctactgccga
     5821 gtgatatcgc tgacgtcatc cttgagggtg aagttcaggt cgtcgagcaa ctcggcaacg
     5881 aaactcaaat ccatatccag atcccttcca ttcgtcaaaa cctggtgtac cgccagaacg
     5941 acgtggtgtt ggtagaagaa ggtgccacat tcgctatcgg cctgccgcca gagcgttgcc
     6001 atctgttccg tgaggatggc actgcatgtc gtcgactgca taaggagccg ggcgtttaag
     6061 caccccacaa aacacacaaa gcctgtcaca ggtgatgtga aaaaagaaaa gcaatgactc
     6121 aggagataga atgatgatta ctctgcgcaa acttcctctg gcggttgccg tcgcagcggg
     6181 cgtaatgtct gctcaggcaa tggctgttga tttccacggc tatgcacgtt ccggtattgg
     6241 ttggacaggt agcggcggtg aacaacagtg tttccagact accggtgctc aaagtaaata
     6301 ccgtcttggc aacgaatgtg aaacttatgc tgaattaaaa ttgggtcagg aagtgtggaa
     6361 agagggcgat aagagcttct atttcgacac taacgtggcc tattccgtcg cacaacagaa
     6421 tgactgggaa gctaccgatc cggccttccg tgaagcaaac gtgcagggta aaaacctgat
     6481 cgaatggctg ccaggctcca ccatctgggc aggtaagcgc ttctaccaac gtcatgacgt
     6541 tcatatgatc gacttctact actgggatat ttctggtcct ggtgccggtc tggaaaacat
     6601 cgatgttggc ttcggtaaac tctctctggc agcaacccgc tcctctgaag ctggtggttc
     6661 ttcctctttc gccagcaaca atatttatga ctataccaac gaaaccgcga acgacgtttt
     6721 cgatgtgcgt ttagcgcaga tggaaatcaa cccgggcggc acattagaac tgggtgtcga
     6781 ctacggtcgt gccaacttgc gtgataacta tcgtctggtt gatggcgcat cgaaagacgg
     6841 ctggttattc actgctgaac atactcagag tgtcctgaag ggctttaaca agtttgttgt
     6901 tcagtacgct actgactcga tgacctcgca gggtaaaggg ctgtcgcagg gttctggcgt
     6961 tgcatttgat aacgaaaaat ttgcctacaa tatcaacaac aacggtcaca tgctgcgtat
     7021 cctcgaccac ggtgcgatct ccatgggcga caactgggac atgatgtacg tgggtatgta
     7081 ccaggatatc aactgggata acgacaacgg caccaagtgg tggaccgtcg gtattcgccc
     7141 gatgtacaag tggacgccaa tcatgagcac cgtgatggaa atcggctacg acaacgtcga
     7201 atcccagcgc accggcgaca agaacaatca gtacaaaatt accctcgcac aacaatggca
     7261 ggctggcgac agcatctggt cacgcccggc tattcgtgtc ttcgcaacct acgccaagtg
     7321 ggatgagaaa tggggttacg actacaccgg taacgctgat aacaacgcga acttcggcaa
     7381 agccgttcct gctgatttca acggcggcag cttcggtcgt ggcgacagcg acgagtggac
     7441 cttcggtgcc cagatggaaa tctggtggta atagcaaaac ctgggccgga taaggcgttt
     7501 acgccgcatt cggcaaccaa cgcctgatgc gacgcttgcg cgtcttatca ggcctacaac
     7561 ggctgtcaaa tgtaggccgg ataaggcgtt tacgccgcat ccggcataaa aacaggttgt
     7621 cattatctga aaggggcgaa agcccctctg attatcgggt ttagcgcgct attgcctggc
     7681 taccgctgag ctccagattt tgaggtgaaa acaatgaaaa tgaataaaag tctcatcgtc
     7741 ctctgtttat cagcagggtt actggcaagc gcgcctggaa ttagccttgc cgatgttaac
     7801 tacgtaccgc aaaacaccag cgacgcgcca gccattccat ctgctgcgct gcaacaactc
     7861 acctggacac cggtcgatca atctaaaacc cagaccaccc aactggcgac cggcggccaa
     7921 caactgaacg ttcccggcat cagtggtccg gttgctgcgt acagcgtccc ggcaaacatt
     7981 ggcgaactga ccctgacgct gaccagcgaa gtgaacaaac aaaccagcgt ttttgcgccg
     8041 aacgtgctga ttcttgatca gaacatgacc ccatcagcct tcttccccag cagttatttc
     8101 acctaccagg aaccaggcgt gatgagtgca gatcggctgg aaggcgttat gcgcctgaca
     8161 ccggcgttgg ggcagcaaaa actttatgtt ctggtcttta ccacggaaaa agatctccag
     8221 cagacgaccc aactgctcga cccggctaaa gcctatgcca agggcgtcgg taactcgatc
     8281 ccggatatcc ccgatccggt tgctcgtcat accaccgatg gcttactgaa actgaaagtg
     8341 aaaacgaact ccagctccag cgtgttggta ggacctttat ttggttcttc cgctccagct
     8401 ccggttacgg taggtaacac ggcggcacca gctgtggctg cacccgctcc ggcaccggtg
     8461 aagaaaagcg agccgatgct caacgacacg gaaagttatt ttaataccgc gatcaaaaac
     8521 gctgtcgcga aaggtgatgt tgataaggcg ttaaaactgc ttgatgaagc tgaacgcctg
     8581 ggatcgacat ctgcccgttc cacctttatc agcagtgtaa aaggcaaggg gtaattacgc
     8641 cccacagtgc tgattttgca acaactggtg cgtctcctgg cgcacctttt tttatgcttc
     8701 cttcctggga tatgagcgat tttttatagt aactcacttc ttcttcacta agaatatcca
     8761 ttatctcaat gccttatcag agattctttt cctttcgccg gtagtgtctg gacattcagg
     8821 ctacttttcc aggttatttt atttctgtta tgcagaggtt ttatgataag tcatatccta
     8881 aattctggcg gcaataactc tttgatgaaa catgatgtgg tgcaaggaaa taatatagta
     8941 gatcttgatt tactacgtaa tttaaatggg gtgccaggtt taaacagaga taactttatt
     9001 tatatcagca atattttttc aaatataaaa caacggaacg aaaaaatcat gcaataaata
     9061 tgtttcgtga agtctcaatc agtaatgata ctataagtgt aaaattctac agaaataaaa
     9121 aaaattgaat gcgcttgcaa ttttctgatg gataaagatg cgcaggggta tatcgacctg
     9181 tctgatttgg atttaacaag ttgtcatttt aaaggtgacg ttatatcgaa ggtgtctttt
     9241 ttatcatcaa atctacaaca tgtaacattc gaatgtaaag aaattgggga ttgcaatttt
     9301 actactgcaa tagttgataa tgtcatattt agatgtcgac gtttacacaa tgtgattttt
     9361 atcaaagcga gtggtgaatg tgtcgatttc agcaaaaata ttcttgatac agttgacttc
     9421 tcgcagagtc aacttggtca tagtaatttt cgcgaatgtc agattagaaa ttcaaacttc
     9481 gataattgtt atctttacgc ttcgcacttc accagagcag agtttctgtc tgccaaagaa
     9541 atatcattta ttaaatcgaa tttgacagct gttatgtttg attatgtgcg aatgtcgaca
     9601 gggaatttta aagattgcat tacagaacaa ttggaattaa ctattgatta ttcagatata
     9661 ttttggaatg aagat
//
LOCUS       DACAOP010000132         9654 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.132, whole genome shotgun sequence.
ACCESSION   DACAOP010000132 DACAOP010000000
VERSION     DACAOP010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9654
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.132"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..273)
                     /locus_tag="IT892_003996"
     CDS             complement(<1..273)
                     /locus_tag="IT892_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP3137141.1"
                     /translation="MSSSLPDDINALKRLLAEQEALNRALQEKLNEREREIDHLQAQL
                     DKLRRMNFGSRSEKVSRRIAQMEADLKALQKESDTLTGRVDDPAVQR"
     gene            complement(322..669)
                     /gene="tnpB"
                     /locus_tag="IT892_003997"
     CDS             complement(322..669)
                     /gene="tnpB"
                     /locus_tag="IT892_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004966400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAP3137142.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTTLKDDPMSGHVF
                     IFRGRNGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLLEGIDW
                     RQPKRLLTSLTML"
     gene            complement(666..1070)
                     /locus_tag="IT892_003998"
     CDS             complement(666..1070)
                     /locus_tag="IT892_003998"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HAP3137143.1"
                     /translation="MKSLTAVRKKSPNYPVEFKIKMVELSHRPEISVAQLAREHGIND
                     NLLFKWRQYWREGKLRPPSTTENNVPELLPITLDAEDVVPTTSPRSQPVAAATPESLN
                     ISCEVTFRHGSLRLNGAISENILNLLIRELKR"
     gene            1204..1485
                     /locus_tag="IT892_003999"
     CDS             1204..1485
                     /locus_tag="IT892_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000910668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137144.1"
                     /translation="MLKELVERTPGYHGWQQEFWLAHCGDFCVFIGYVGWNDIKDRLD
                     EFANLEEDCENFGIRNSDLAKCLQKGGHCQGYLFRCLHCGKLRLWGDFS"
     gene            complement(1547..2269)
                     /locus_tag="IT892_004000"
     CDS             complement(1547..2269)
                     /locus_tag="IT892_004000"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAP3137145.1"
                     /translation="MKLIITEDYQEMSRVAAHHLLGYMSKTRRVNLAITAGSTPKGMY
                     EYLTTLVKGKPWYDNCYFYNFDEIPFRGKEGEGVTITNLRNLFFTPAGIKEENIQKLT
                     IDNYREHDQKLAREGGLDLVVLGLGADGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA
                     HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASV
                     LQLHPSLMVIADKAAAAELALG"
     gene            complement(2346..3452)
                     /locus_tag="IT892_004001"
     CDS             complement(2346..3452)
                     /locus_tag="IT892_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001340430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAP3137146.1"
                     /translation="MNIKIAALTLAIASGISAQWAIAADMPASPAPTIPVKQYVTQVN
                     ADNSVTFRYFAPGAKNVSVVVGVPVPDNIHPMTKDEAGVWSWRTPILKGNLYEYFFNV
                     DGVRSIDTGTAMTNPQRQVNSSMILVPGSYLDTRSVAHGDLIAITYHSNALQSERQMY
                     VWTPPGYTGMGEPLPVLYFYHGFGDTGRSAIDQGRIPQIMDNLLAEGKIKPMLVVIPD
                     TETDAKGIIPEDFVPQERRKVFYPLNAKAADRELMNDIIPLISKRFNVRKDADGRALA
                     GLSQGGYQALVSGMNHLESFGWLATFSGVTTTTVPDEGVAARLNDPAAINQQLRNFTV
                     VVGDKDVVTGKDIAGLKTELEQKKLTLITRNIRV"
     gene            complement(3479..5095)
                     /locus_tag="IT892_004002"
                     /pseudo
     CDS             complement(3479..5095)
                     /locus_tag="IT892_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418176.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
     gene            complement(5164..6576)
                     /locus_tag="IT892_004003"
     CDS             complement(5164..6576)
                     /locus_tag="IT892_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglB"
                     /protein_id="HAP3137147.1"
                     /translation="MKAFPETFLWGGATAANQVEGAWQEDGKGISTSDLQPHGVMGKM
                     EPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCLRISIAWARIFPQGDEVEPNEAG
                     LAFYDRLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRY
                     QHKVALWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLLP
                     EAKIGNMLLGGLVYPLTCQPQDMLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNI
                     TIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNILNMIPNPHLKSSEWG
                     WQIDPVGLRVLLNTLWDRYQKPLFIVENGLGAKDSVEADGSIQDDYRIAYLNDHLVQV
                     NEAIADGVDIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGW
                     YAEVIKTRGLSLKKITIKAP"
     gene            complement(6595..8472)
                     /gene="bglF"
                     /locus_tag="IT892_004004"
     CDS             complement(6595..8472)
                     /gene="bglF"
                     /locus_tag="IT892_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIABC"
                     /protein_id="HAP3137148.1"
                     /translation="MTELARKIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLK
                     KTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGLDEKAQQAPENDDKGNLLNRFVY
                     VISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFWFFPIILG
                     YTAGKRFGGNPFTAMVIGGALVHPLILTAFENGQKADALGLDFLGIPVTLLNYSSSVI
                     PIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPVTFLLVGPLSTWISELIAA
                     GYLWLYQAVPAFAGAVMGGFWQIFVMFGLHWGLVPLCINNFTVLGYDTMIPLLMPAIM
                     AQVGAALGVFLCERDAQKKVVAGSAALTSLFGITEPAVYGVNLPRKYPFVIACISGAL
                     GATIIGYAQTKVYSFGLPSIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMLH
                     FITAKRQPAQGAPQEKTPEVITPPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIA
                     ILPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFSAHVNV
                     GDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQISAGEPLLSII
                     R"
     gene            complement(8606..9442)
                     /gene="bglG"
                     /locus_tag="IT892_004005"
     CDS             complement(8606..9442)
                     /gene="bglG"
                     /locus_tag="IT892_004005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator BglG"
                     /protein_id="HAP3137149.1"
                     /translation="MNMQITKILNNNVVVVIDDQQREKVVMGRGIGFQKRAGERINSS
                     GIEKEYALSSHELNGRLSELLSHIPLEVMATCDRIISLAQERLGKLQDSIYISLTDHC
                     QFAIKRFQQNVLLPNPLLWDIQRLYPKEFQLGEEALTIIDKRLGVQLPKDEVGFIAMH
                     LVSAQMSGNMEDVAGVTQLMREMLQLIKFQFSLNYQEESLSYQRLVTHLKFLSWRILE
                     HASINDSDESLQQAVKQNYPQAWQCAERIAIFIGLQYQRKISPAEIMFLAINIERVRK
                     EH"
BASE COUNT         2460 a         2452 c         2188 g         2554 t
ORIGIN      
        1 gcgctgcacg gccgggtcgt caacccgacc ggtaagggta tcactttctt tctgaagtgc
       61 cttcaggtca gcttccatct gtgcgatacg acgggagact ttttccgagc ggctgccgaa
      121 gttcatccgg cgcagcttat ccagctgtgc ctgcagatgg tctatttcgc gttcacgctc
      181 gttcagcttt tcctgcaggg cacggttcag cgcctcctgt tcggcaagga gacgtttcag
      241 tgcattgata tcgtcaggaa gtgagctgct cataccgggt atattaccag gctcattcag
      301 cgtcgactag gataaagagg cttacaacat agtcagggac gtaagcagtc ttttaggctg
      361 ccgccagtcg ataccttcca gcagcatcgc cagctgtgcc ggtgtgagga acactttgcc
      421 atcccgggct gacggccagg cgaagcggcc gcgctccagc cgtttggtca gcagacacag
      481 tccatcgccg gtagaccaga ggagctttac ctgactgcca ttacgcccac ggaagataaa
      541 aacgtgacct gacatcggat cgtctttcag cgtcgtctgc acctttgccg ccaggccgtt
      601 gaagccgttt ctcatatcgg tgatgccagc gaccagccag atctttgtcc ctgatggtaa
      661 tgggatcaac gtttgagctc ccgtatcagc aggttcagga tattttcgct gatggcacca
      721 ttcagacgga gtgatccgtg ccggaacgtc acttcacagc tgatattgag tgattcaggt
      781 gtcgcagcag ctacaggttg tgaccggggg gaggttgtag ggacaacatc ttcggcatca
      841 agtgttatcg ggagcagctc aggcacgttg ttttctgttg ttgaaggagg acgtagtttt
      901 ccttcgcgcc agtactggcg ccacttgaac agcaaattat cgttgatccc atgctcacga
      961 gcgagttgcg ctacggagat ctctggtcga tgcgagagtt caaccatttt gattttgaac
     1021 tcaacgggat aattagggct ttttttacgc actgcggtta atgatttcat ggattgcgtc
     1081 caccatattt ggtgtccact attctctcag gaatttcagg atctgccaga cggtgctgag
     1141 acgacgctta cgtatgatga agaggacgaa tttgccggta ttaagaacac atatcctgat
     1201 gaaatgctga aagagttggt tgaacgcacg ccaggttatc atggatggca gcaggaattc
     1261 tggctcgcgc attgtggcga tttctgtgtt tttatcggct atgtgggctg gaatgatata
     1321 aaagatcgcc tcgatgaatt tgccaacctt gaagaagatt gtgagaattt cggtattaga
     1381 aattctgatc tagctaaatg cctgcaaaag ggtggtcatt gtcagggtta tctcttccgc
     1441 tgtctccact gcggcaagct gagactgtgg ggtgattttt cgtagttatt taaataatga
     1501 gaacaggccg gagcgtaatt cacacatccg gccttatttc ttaagcttaa ccgagtgcta
     1561 attctgcggc agcggcttta tcagcgatta ccatcagcga aggatgcagc tgcaacacgg
     1621 aagctggaac atcttcggta accggacctt gcagaacatt tttcagtgcc tgcgctttac
     1681 ccgcgccgct gacaattatc agcaagtttt tcgccgccat gatgcttttc ggccccatcg
     1741 tcacgtagct gtcaggcact aacgaaaagt cgccgcccaa ctcgccatgc gccacaatat
     1801 caaccatctc tccctggatc gggaactcca cggtttgctc atggaaatgg gtcgtattcg
     1861 gcaaattgcc acaaaaatga ccatctgcac ctaatcccag caccaccaaa tccagtccgc
     1921 cttcacgcgc cagtttctga tcatgctcgc ggtagttatc aatagtgagc ttctggatat
     1981 tctcttcttt gatccccgca ggggtgaaaa acagattacg cagattggta atcgttacgc
     2041 cttctccctc tttgccgcga aatggaattt catcaaaatt atagaaatag cagttatcgt
     2101 accagggctt acctttaacc agggtggtga ggtattcata catgcctttg ggcgtgctac
     2161 cggcggtaat tgccaggtta acacgacgcg tcttcgacat ataaccaagc agatggtgtg
     2221 ccgcgacacg gctcatttcc tggtaatctt cggtaatgat taatttcatc ttaatgcctt
     2281 attttattta aataatttct gtacaaaggc tgcataggct ggtcgccaga catccatttc
     2341 atggttcaga cccggatatt cctggtaatc aaagttaatt ttttctgctc aagctcagtt
     2401 ttcagcccgg cgatatcctt gccggttacg acatctttat cccccacaac cacagtaaaa
     2461 ttacgtagtt gctggttgat agctgccgga tcgttcagtc gggccgcgac accttcatcc
     2521 ggtacggttg tcgtggtaac accactgaat gtggccagcc agccaaagct ttccagatga
     2581 ttcattccgg aaaccagcgc ctggtacccg ccttgtgaaa gccctgccag cgcgcggcca
     2641 tcggcatctt tacggacatt aaaacgcttg ctaatcagcg ggataatatc gttcatcagt
     2701 tcgcgatctg ccgctttagc attcagcgga taaaagactt tacgtctttc ctgaggcacg
     2761 aaatcttcgg gaataatgcc cttcgcatcg gtttctgtat ccgggatcac caccagcatc
     2821 ggtttaattt tcccttcagc aagcaggtta tccatgattt gcgggatacg cccctgatcg
     2881 atagcggaac gtccggtatc accaaagccg tgatagaaat agagcactgg caaaggctcg
     2941 cccatgccgg tgtatcctgg cggggtccag acatacatct gacgttcaga ttgcaatgcg
     3001 ttggagtggt aagttatggc gatcaaatca ccatgcgcaa cagaacgcgt atccagataa
     3061 ctgcctggca ccagaatcat actggagtta acctggcgct gaggattagt cattgcggtg
     3121 cctgtatcaa tgctgcgtac accatcaaca ttgaaaaaat actcgtacag gttgcctttc
     3181 aggataggtg tgcgccacga ccagactcct gcttcgtctt tggtcatcgg gtgaatattg
     3241 tccggaaccg gaacacccac cactacagag acattttttg ccccaggggc aaagtagcga
     3301 aaggtcacgc tgttatcggc attgacctga gtcacatact gtttcaccgg gatagtgggt
     3361 gccgggctgg ctggcatatc cgctgctatg gcccactgag cagaaatacc gctggcaata
     3421 gccagcgtta aagcagcaat ttttatattc atcgtaatat tcctttcatt aagttccatt
     3481 accaccagat ttcagcctgg gcaccgacag caaactggtc gtctttattg tcttcaaagg
     3541 tgaagccatc cagttcgttt tccagggctt tgatatacgt ggcgtagaaa cgaatttccg
     3601 gacgcgaggt caacatactg gtattgactt taaaggtatg gaagagcgtg gttttataac
     3661 cagactcatt aaatttatta ctattcgcat ctttgttttg ctgggtgaaa tagcccagtt
     3721 caacacctgt ctggttatat tggtcccaaa tataggccgg gcgaacaacc gcacgaatag
     3781 attcgaaatc agagtgggcg cctgtttcgt agctatatat atcgttaccg aaggagtaaa
     3841 caatcgcgtt agctacaatg aaatgatcgc caatataggc ttcgccctgc gaagtcagac
     3901 gtaccgctgt tccgccggtg tgatcaccat aataacgacc attaaaggtg gtaaatggac
     3961 ttgcgccagc ataacggcca aagttactgg cgatagagtt attcgcgacc aggaaggaga
     4021 attcgttgaa gccaccttta tcaaatttct gcgttaaaga tgtgccaaac atccaggtat
     4081 ctttccagtc ataatacccg ttattatcct gattatcttt ttccgatgcg ctttcgtttg
     4141 ccgtgacata acgaccactt accattaagg tggctttatc ctataacggg atatctttat
     4201 agcgtaaatc aatggtattg gtattaatct gctgtttgtt ttgcaggctg cgatcgtaat
     4261 catcgacatc ttcgcgaacc agcgcgatat caattttacc cggaccgact ttccagtttt
     4321 ccagacctac acccgctgcg gcatcagtac gctgcgtttt ccagtcaagc atctggattt
     4381 caattttcgg cgcaccgtgt ttacccaccc agaaatcagc ctctggcgca aagggcagga
     4441 aacctttggt ggtaacgtac atatcggaga actgcatata gttctcgcca ccggcgttat
     4501 cgccaaacca gccggtagag tactgctgac caacgttacc atccatcatc acaacggcat
     4561 caacccgttt gccgttttcg ttgtagacac gttgttttaa ctgcaaatca aaccagccgg
     4621 agtattcgtt accaaagcgg cccagagaac caatcgccca tgatttaggt gaaccatgag
     4681 aggcggtccc ccaaccagaa cggtaatagc cgttgtaact aaagccaatt tcatctttca
     4741 caaatttact gaaatctttc agagtcatgg aagaataaat cgagcctgtc tcactggcat
     4801 ttttctcttc atttttgacc agtacagcat caggttttgc ggcactactg gtcgggaacg
     4861 gattggcggc atacccttga tcattcgtac ttacgctacg attcaccgtc gctggcgtat
     4921 actttttctt ctcttcatct ttatactttt tgagttcgct ttgcgtttct cttaacgcct
     4981 tttctaataa ctcaaggcgt tgttccaccg ttaatgattc agccaatgat tgtgcagaaa
     5041 aggctaacgg tgccattaat aagatggcag aggtaataag atttcgtcta aacataatat
     5101 ccctttatgg tgcaaagaaa gaattaacgc atcgcatcca gactgttctg aatgcgacga
     5161 taattaaggt gctttaatgg ttattttttt taatgacagc ccccgcgtct tgatcacctc
     5221 tgcataccat ccgaagcttt tcttgcgtgt tcttgtgagg cttccttcgc cattatcatc
     5281 acgatccaca taaataaagc cgtagcgctt agacatttgt gaatgagatg cactgactaa
     5341 atcaattggc ccccaactgg tgtaccccat aatatccaca ccatcggcaa tcgcttcatt
     5401 tacctgtacc aggtgatcgt ttaaataggc aattcgataa tcgtcctgta tcgaaccatc
     5461 cgcttcaacg ctgtcttttg cgcctaatcc gttctcgaca ataaataacg gtttttgata
     5521 acgatcccaa agcgtattta acagaacccg taatccaacc ggatcaattt gccaccccca
     5581 ctctgaactt ttcagatgcg gattggggat catattcagt atgttgccct gcgcattttt
     5641 attaatgctt tcgtcgtggg aaacacaacc agtcatgtaa taactaaaag agatgaaatc
     5701 gacggtatgt tttaaatctt ctgcgtcact ttcagtcatc tcaatggtga tattgtggtc
     5761 gcggaagaaa cgctgcatat agccgggata ctggccacgc gcctgaacat caccaaagaa
     5821 catccagcgc cggttctctt ccatggcctg caacatatcc tgtggctggc aggtgagggg
     5881 gtaaaccagc ccaccgagaa gcatattgcc gattttcgct tcggggagca ggctatgaca
     5941 ggctttaact gcccgcgcac tggcaaccag ttgatggtgg atagcctgat aaacttccgc
     6001 ctcgccactc tcttctgcca gccccacgcc cgtgaatggc gcgtgtaacg acatgttgat
     6061 ttcattaaac gtcagccata acgccacttt atgttggtag cgagtaaaga ccgtgcgggc
     6121 gtaatgctcg aagtgatcga tgaccgctcg attagcccaa ccgccgtagt ttttcaccag
     6181 cccatatggc atttcgtaat gggataacgt taccagcggc ttgatccccg cctgcgccat
     6241 ttcatcaaac agccgatcgt aaaacgctaa ccccgcttca ttcggttcga cttcgtcgcc
     6301 ctgagggaaa attcgcgccc aggcaatgga aatacgcaga caggtgaagc ccatctcggc
     6361 aaataacgcg atatcttccg ggtaacggtg ataaaaatcg atggcgacat ctttgatatt
     6421 ctctttcccc aggatgcgcg gttccatttt tcccattacg ccatgaggct gtaaatctga
     6481 ggtcgagatc cctttgccat cttcctgcca ggcaccttcc acctgattgg cagctgttgc
     6541 gccaccccaa agaaatgttt ctggaaatgc tttcataatt aactcctttt atcgttagcg
     6601 aatgatggat aacagcggtt cacctgcgct tatctgcgcc gtgccgtggg gtaatacgtc
     6661 cgtaaaatca tcgctattac tgattaatac cggcgtcgtc agatcaaatc cggcctcgcg
     6721 aatagcaggg atatcaaaag aaatcagccg atcgcctgta ttgaccttgt cacccacgtt
     6781 gacgtgagcg gaaaagaatt tgccgtccag ttttacggtg tcgataccga catgaatcag
     6841 gatctccaca ccatcatctg actcaatgcc aatggcgtgt aatgtggcga acaacgaagc
     6901 aattcgaccc gcaaccggag aacgcacttc accaaccgag ggcagaatgg caataccttt
     6961 acccaacagg ccactggcaa acgtggtatc agcgacgtga atgagcggca caatctctcc
     7021 cgtcatcggt gaacagatac cgccctgctc aggtggtgta ataacctctg gtgttttctc
     7081 ttgcggggca ccctgcgctg gctgacgttt agcggtgatg aaatgaagca tcaccgtacc
     7141 gacaaatgcg caaccgatgg caatgacacc gccaataacg ctggcccaga cggtgaaatc
     7201 aattcccgtt gacgggatgg tttgcatgaa ggtgaaaata cttggcaaac caaaggagta
     7261 gactttcgtt tgcgcgtagc caataatggt ggcccccaaa gccccactga tacaggcgat
     7321 aacaaagggg tacttacgcg gcaggttgac gccatatacc gctggttcgg tgataccaaa
     7381 cagactcgtc aacgccgctg atcccgccac cacttttttc tgcgcatcgc gttcgcagag
     7441 gaagacgccg agcgccgccc cgacctgcgc cataatggcg ggcattaaca gcgggatcat
     7501 ggtgtcgtag cccagcacgg tgaagttatt gatacacagc ggcaccaggc cccagtgcag
     7561 tccgaacatg acgaagattt gccagaagcc gcccattacc gcgcccgcaa atgcaggaac
     7621 cgcctgataa agccagagat aaccggcggc aatcagttcg cttatccagg ttgatagcgg
     7681 ccccaccagc agaaaggtga cgggtgtgat aaccatcaga catagcaatg gtgtgaagaa
     7741 atttttgatt gccgacggta accacgcatt aagtcggcgt tccagaatgc tgcacaacca
     7801 ggcagaaaaa ataatgggaa taaccgatga cgagtaattc aacaatgtga ccggaatacc
     7861 caggaaatcc agccccagcg catccgcttt ttgcccgttc tcgaaagcag tcagaattaa
     7921 tggatgcact aacgctccac caatcaccat ggcagtaaat ggattaccgc cgaagcgttt
     7981 ccccgcggtg tatcccagga ttatcgggaa gaaccaaaac aaggcatcac tggcgctgaa
     8041 taaaattaaa taagtaccac tttgttcggt cgtccactga aaagtgagcg ccagagccag
     8101 catacctttc aagatcccgg ttgccgccat caaaccgatc agaggcgtaa aaatacctga
     8161 aataacataa acaaagcggt ttagcagatt acctttatca tcattttccg gtgcctgttg
     8221 cgctttttcg tcaaggcctg ccacactgtt aaccgccagg aagacatcgg ccacatggtt
     8281 acctatgacc acctgaaact ggccaccgct ttccaccacc ataataatac cgggggtctt
     8341 tttcagtacc tctgcttgcg ctttgctttc atcctttaat ttaaaacgta atcgcgttgc
     8401 gcaatgcatc agactcacaa tgttatctgc gcccccgact cctgcgacta tttttctggc
     8461 taactccgtc ataacttgcc ctctaccgct ttgcggcaaa actccaaaaa aaaacctgaa
     8521 aaaaacggcc tgacgtgaat caagcaattt ttttcaggtt ttgcccgctt agtgcggtaa
     8581 caatccttta ctcagtaata atatttcagt gttctttgcg cacgcgctct atatttatgg
     8641 ctaaaaacat aatctctgcg ggtgaaattt tacgttgata ctgcaaacca ataaaaatgg
     8701 cgatccgttc cgcacattgc catgcttgcg ggtaattttg ttttactgct tgttgtaatg
     8761 attcatcact atcgttaatt gaagcatgtt caagaatacg ccaggataaa aacttcagat
     8821 gtgtaaccag tcgctgataa ctcaagcttt cttcctggta attaaggctg aactgaaatt
     8881 ttattaattg cagcatttcg cgcattaact gcgtgacacc tgcaacatcc tccatatttc
     8941 cgctcatttg ggcactgacc agatgcatgg caataaagcc cacttcatct ttcggtaact
     9001 gcacgcccaa ccgtttatca ataatggtta acgcttcttc ccctagctgg aactctttcg
     9061 ggtaaagccg ctggatatcc cacagcaacg ggttgggcag caacacgttt tgctgaaagc
     9121 gtttaatcgc aaactggcaa tggtcagtta gcgagatata aatactgtcc tgtaattttc
     9181 ccaagcgctc ctgcgctaaa gagataatac gatcacaggt tgccatcacc tcaagaggaa
     9241 tatgacttaa gagttcgctt aatcgcccgt tcagttcatg actgctcaag gcatactctt
     9301 tttctattcc acttgagtta attctttcgc cagcgcgttt ttgaaagcca attccgcgcc
     9361 ccatgacgac tttttcccgc tgttgatcat caataaccac cacaacatta ttgttgagaa
     9421 ttttggtgat ttgcatgttc atagcaagga ccttttttat aaacaaaaaa acccgacttc
     9481 accagtattc tctggttatg tcaggttttg cctgcgaatg cagtaacaat ccagtcattt
     9541 attaatggtt tttataacga acatccaggt tcggaaatta atttaattgc gtgcagagaa
     9601 aatagcaatg cgctattgat aaaaatatga ccatgctcgc agttattaac tttg
//
LOCUS       DACAOP010000133         9530 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.133, whole genome shotgun sequence.
ACCESSION   DACAOP010000133 DACAOP010000000
VERSION     DACAOP010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9530
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.133"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            196..699
                     /locus_tag="IT892_004006"
     CDS             196..699
                     /locus_tag="IT892_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin-like protein"
                     /protein_id="HAP3137150.1"
                     /translation="MATAGMLLKLNSQMNREFYASNLYLHLSNWCSEQSLNGTATFLR
                     ALAQSNVTQMMRMFNFMKSVGATPIVKAIDVPGEKLNSLEELFQKTMEEYEQRSSTLA
                     QLADEAKELNDDSTVNFLRDLEKEQQHDGLLLQTILDEVRSAKLAGMCPVQTDQHVLN
                     VVSHQLH"
     gene            complement(778..1029)
                     /locus_tag="IT892_004007"
     CDS             complement(778..1029)
                     /locus_tag="IT892_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2766 domain-containing protein"
                     /protein_id="HAP3137151.1"
                     /translation="MSQPLNADQELVSDVVACQLVIKQILDVLDVIAPVEVREKMSSQ
                     LKNIDFTNHPAAADPVTMRAIQKAIALIELKFTPQGESH"
     gene            complement(1144..1230)
                     /gene="azuC"
                     /locus_tag="IT892_004008"
     CDS             complement(1144..1230)
                     /gene="azuC"
                     /locus_tag="IT892_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein AzuC"
                     /protein_id="HAP3137152.1"
                     /translation="MKLRKILKSMFNNYCKTFKDVPPGNMFR"
     gene            1493..1816
                     /locus_tag="IT892_004009"
     CDS             1493..1816
                     /locus_tag="IT892_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137153.1"
                     /translation="MRLLILTLSLITLAGCTVTRQAHVSEVDAATGIVRLVYDQAFLQ
                     HAHTDRYVSRGIADRACQQEGYTHAVPFGQPVGNCSLFAGSLCLNTEFTLSYQCHHSA
                     FPVFL"
     gene            1987..2484
                     /gene="ftnA"
                     /locus_tag="IT892_004010"
     CDS             1987..2484
                     /gene="ftnA"
                     /locus_tag="IT892_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin"
                     /protein_id="HAP3137154.1"
                     /translation="MLKPEMIEKLNEQMNLELYSSLLYQQMSAWCSYHTFEGAAAFLR
                     RHAQEEMTHMQRLFDYLTDTGNLPRINTVESPFAEYSSLDELFQETYKHEQLITQKIN
                     ELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGEGLYFIDKELST
                     LDTQN"
     gene            complement(2522..2761)
                     /locus_tag="IT892_004011"
     CDS             complement(2522..2761)
                     /locus_tag="IT892_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family protein"
                     /protein_id="HAP3137155.1"
                     /translation="MDSIHGHEVLNMMIESGEQYTHASLEAAIKARFGEQARFHTCSA
                     EGMTAGELVAFLAAKGKFIPSEDGFSTDQSKICRH"
     gene            2953..4164
                     /gene="tyrP"
                     /locus_tag="IT892_004012"
     CDS             2953..4164
                     /gene="tyrP"
                     /locus_tag="IT892_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine transporter TyrP"
                     /protein_id="HAP3137156.1"
                     /translation="MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLW
                     ALMCYTALLLLEVYQHVPADTGLGTLAKRYLGRYGQWLTGFSMMLLMYALTAAYISGA
                     GELLASSISDWTGISMSATAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVVM
                     LVLLLPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMDGNVRKLRWVF
                     ITGSAIPLVAYIFWQVATLGSIDSTTFMGLLANHAGLNGLLQALREMVASPHVELAVH
                     LFADLALATSFLGVALGLFDYLADLFQRSNTVGGRLQTGAITFLPPLAFALFYPRGFV
                     MALGYAGVALAVLALIIPSLLTWQSRKHNPQAGYRVKGGRPALVVVFLCGIAVIGVQF
                     LIAAGLLPEVG"
     gene            complement(4226..4891)
                     /gene="yecA"
                     /locus_tag="IT892_004013"
     CDS             complement(4226..4891)
                     /gene="yecA"
                     /locus_tag="IT892_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YecA"
                     /protein_id="HAP3137157.1"
                     /translation="MKTGPLNESELEWLDDILTKYNTDHAILDVAELDGLLTAVLSSP
                     QEIEPEQWLVAVWGGADYVPRWASEKEMTRFMNLAFQHMADTAERLNEFPEQFEPLFG
                     LREVDGSELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFERVEKMS
                     PEAFEESVDAIRLAALDLHAYWMAHPQEKAVQQPIKAEEKPGRNDPCPCGSGKKFKQC
                     CLH"
     gene            complement(5322..6503)
                     /locus_tag="IT892_004014"
     CDS             complement(5322..6503)
                     /locus_tag="IT892_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001384558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HAP3137158.1"
                     /translation="MIYQCDTCSRTTFEVNCPWCSGVSPVKTSAWGSASSTSQAIDIQ
                     RMTPLNPSFYPEFQYRSKGVLKDLFGKKKEQAQLNQLLENVLEKYSSLKDPYFTNFIY
                     TSRFSHNNKSEADYSTDNGTYSELQLFREVLVRKGFNELEELPELLDKLLLTTSFNAL
                     YYGFAKEVKRHIKSTLTESLKSWIEEAGTTFRADLSLFLFYIWSNKIEFSSVEFNEKA
                     EATPGVPLVSFDEVKKYLAVCEHIYFDILVDRLATRLEHFNPNKFVTMYLVDAMDGFQ
                     FEDFLVEVFQTMGYDVKETKRTQDQGADLFVTRFGKDMVIQAKNYSGSVGNSAVQQVI
                     SAKTFYGCDEAMVVTNSYFTRSAKELAESALVRLIDRDELQKYLDDYNQKIIEDFQSN
                     S"
     gene            complement(6608..7735)
                     /locus_tag="IT892_004015"
     CDS             complement(6608..7735)
                     /locus_tag="IT892_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HAP3137159.1"
                     /translation="MRSETFFVKFIEQLKGVSVEDDVEFNFFELGGSGYLENPTTDLM
                     ALFMGAQKMVPPWLLKALLCCLDDSLDVDEIDFTSLELMREARTEDGKYIDILIRHDE
                     FIIGIEHKVLADTYNPFPSYVSLIDSYGGNNQKLFRCILKPDGNSAKGVDGWQLINYS
                     LLLETAIRRLGLEMMNQEFSKWTFFYQEFLSHLKKLSEVSMDKVSDKNVEFVTENFTA
                     LIKSVQLLEMYQNAITEEAKSVVSEVLPDIHIATGINNWKGYYKAIHLMPGCWGQGKT
                     GITLVYRPSEDGRDEAEFYVYGWIHSDDYPEVNALKEEIRVALSAGDFIPTASPEDYE
                     VSITGKGKVLELSFWGNTRSKKDALVLLKDMTKWMDSKIRT"
     gene            complement(7794..>9530)
                     /locus_tag="IT892_004016"
     CDS             complement(7794..>9530)
                     /locus_tag="IT892_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003679974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HAP3137160.1"
                     /translation="WGEKHIEELVTDLTSAFLNEYTVGDSREQGENYNNYYLGPFVVS
                     SKDGKRSIIDGQQRLTSLTLFLIYLHNLQKELKYEEKIESMIFSELRGSKSFNIVVED
                     RIPCMEALFNFGSYSLVDGDDESTHNMVERYQNITDAFPDELKGQAFPFFIDWLKYNV
                     IMVEIVAYSDENAYTIFETMNDRGLNLTPSEMLKGFLLSRFHQGDKRQKANELWKKAM
                     MDLKNYDKDEDQRFFQSWLRAQYADTIRPGKAGSKNEDFEKIGTRFHSWVRDNLQEVG
                     LDPDNGETFERFIQKNFLFYLNAYTQILNAERALTHQLEYVFYIHHWGIAPTLSFPLM
                     LAPLNVGDSPEAVIAKINLVARYIETFVVRRSVNFRKFSASSIRYTMYSLVKEIRGKS
                     IEELKDLLSKKLSEMPDTFAGMKEFRLHGQNYRFVKFLLSRITAWVEQQAGMSTTFIT
                     YYQPEHGKPFEVEHIWADKYERYSDEFEQEHEFNNYRNRLGDLVLLPRGSNQSYGDLC
                     YDQKQPHYIKENLLAKSLCPLAYMNNPNFNQLRNVFGLPFKPHDSFKKQDVDERQSLY
                     KIICENIWDHNL"
BASE COUNT         2611 a         2187 c         1898 g         2834 t
ORIGIN      
        1 tgtaaaaata tataaacttg atgatttaag cattttctta tacccgttca gacgttattc
       61 ttatttcaga tcatcgtcag aattgactcc acgatcacat ttcggaccgg cagaaaggaa
      121 ttattctgca aacagtaatt atggtgtttt gatttatctt gcacctctcc acttctggat
      181 ataaggatat taggtatggc aaccgctgga atgcttctca aactcaactc tcaaatgaac
      241 cgcgagtttt acgcatccaa tctctacctt cacctgagta actggtgttc tgaacagagt
      301 ctgaacggca ccgccacttt ccttcgcgcc ctggcacaga gtaatgtgac ccaaatgatg
      361 cgcatgttta actttatgaa gagtgtcggc gctaccccca tcgttaaagc cattgatgtt
      421 cccggtgaaa aactgaactc tctggaagaa ctgttccaaa aaacgatgga agaatacgag
      481 caacgttcta gtacgttggc acagttagcc gatgaagcga aagaactgaa tgatgattca
      541 accgtcaatt tcctgcgcga tctggaaaaa gaacagcagc atgatggtct gttgctgcaa
      601 accattcttg atgaagtgcg cagtgcgaaa cttgcgggta tgtgccctgt gcagaccgac
      661 caacatgttc tgaatgtcgt gtcacaccag ctgcattgat catcatcggc gctaatgcat
      721 tgcgccgatg aaggttttga gaaaccgctg cctcatctgt ttgaagcagc ggttttttta
      781 atgggattca ccctgtgggg taaacttgag ttcaataagc gcgatggctt tttggattgc
      841 ccgcatggtg accgggtctg cggcggcggg atggttagta aagtcgatat tcttcagctg
      901 actggacatt ttttcacgaa cttcaacggg cgcgattaca tcgagaacat ccagaatttg
      961 tttgataacc aactggcaag caaccacatc agaaaccagt tcctgatcgg cattcagcgg
     1021 ctgggacatc gtaaactcct gatagcattt tgaaagccgt tatagtagcg gcttcacatc
     1081 ttcagcgata gtcacatcca ccgtcatcag gacacaaaaa aacctgccgg agcaggtttt
     1141 ttgttatcgg aacatattgc ctggcggtac gtctttgaac gtcttgcaat agttattgaa
     1201 catacttttc aggattttgc gcagtttcat cgcggcactc cgaccatttg ttatacaggt
     1261 gttattgtct ttgcgcttat aatatgacaa ccatcacaaa aatcaatctt tatgtgatgc
     1321 aaatcacata aatacccctt taatgttata aaaatgataa tcaaaaaaca gcccccctat
     1381 ttctgacacc tacagatggc aagaaatagc gcctgccagg cgtcttttcc ggccattgtc
     1441 gcagcactgt aacgcgtaaa atagtgcttt ctcttactct tctggctgga ccatgagact
     1501 tctgattctg actctttcat taataacgct ggcggggtgt acggttactc gccaagccca
     1561 tgtgagcgaa gttgacgcgg caacaggtat tgtacggtta gtttatgacc aggctttttt
     1621 gcagcatgcc cataccgatc gttatgtcag tcgcgggatc gccgatcgcg catgccagca
     1681 ggaaggctat acccacgcgg tcccctttgg tcagccagta ggcaactgta gcctttttgc
     1741 gggttcctta tgtttgaata cggaattcac tttgtcatat cagtgccatc attccgcctt
     1801 ccctgtcttt ctctaaatat tttaatcagc gaggggatct tcgctgatta aagaaatagc
     1861 ggtaatgcgt tttattccca ttcgtatttt taataattga agtttatatt ttaccttttg
     1921 caaataataa aataacaaat tatagtgacg ccacagcaac aaatataacc tttgtggagc
     1981 actatcatgc tgaaaccaga aatgattgaa aaacttaatg agcagatgaa cctggaactg
     2041 tactcttcac tgctttatca gcaaatgagc gcctggtgca gctatcatac cttcgaaggt
     2101 gctgccgcgt tcctgcgccg tcacgcccag gaagagatga cgcatatgca gcgtctgttt
     2161 gattacctga ctgataccgg caatttaccg cgtattaata ccgttgaatc tccgtttgct
     2221 gaatattcct cacttgatga attattccag gaaacctata aacacgaaca attaatcacg
     2281 cagaaaatta acgaactggc tcatgctgca atgaccaatc aggactaccc aacatttaat
     2341 ttcctgcaat ggtatgtttc tgagcagcat gaagaagaga aactgttcaa atcgattatt
     2401 gataaattaa gcctggcagg caaaagcggc gaaggtctgt attttatcga caaagaactc
     2461 tctaccctcg acacacaaaa ctaatgctct caggcggcag gttttctgcc gccgtttcaa
     2521 atcagtgacg gcaaatctta ctctgatcgg tcgaaaaacc gtcttctgaa ggtataaatt
     2581 tgccttttgc tgccagaaac gctaccagct ctcccgcagt catcccttct gccgagcagg
     2641 tgtgaaaacg tgcctgttca ccaaaacgcg ctttaattgc tgcttccaga ctggcatgcg
     2701 tatattgctc gcctgattca atcatcatat ttaacacttc atgaccgtga atagagtcca
     2761 tcgttcctcc tcaaaaaaaa gcctagcgta gcgattaccg cttatgaaga ctttgcgcca
     2821 gcgcaggact gaatgctttt tattgtacat ttatatttac accatatgta acgtcggttt
     2881 gacgaagcag ccgttatgcc ttaacctgcg ccgcagatat cactcataaa gatcgtcagg
     2941 acagaagaaa gcgtgaaaaa cagaaccctg ggaagtgttt ttatcgtggc gggaaccaca
     3001 attggcgcag gcatgctggc aatgccgctg gctgcggccg gtgttggttt tagcgttacg
     3061 ttaatcttgt tgattgggct ttgggcgttg atgtgctaca cggcgctatt actgctggag
     3121 gtgtaccagc atgttccggc agataccggt ctgggcacgc tggcaaaacg ctatctggga
     3181 cgctacggtc aatggctgac gggcttcagt atgatgttat taatgtatgc tctgactgcg
     3241 gcatacatca gcggtgccgg tgaattgttg gcctccagca tcagcgactg gacaggtatt
     3301 tcaatgtcgg caaccgctgg cgtgctgttg ttcacttttg ttgccggtgg cgtggtttgt
     3361 gttggaacat cgctggtcga tttatttaac cgttttctgt tcagcgccaa aattattttt
     3421 ctggtggtga tgctggtatt gctgctaccg catattcaca aagtgaatct tttaaccctg
     3481 ccgttgcaac aggggctggc tctgtcagca atcccggtga tttttacctc atttggtttt
     3541 cacggtagcg tgccgagtat tgtcagctat atggatggca acgttcgtaa gctacgctgg
     3601 gtgtttataa ccggtagtgc gatccccctg gtggcatata ttttctggca ggtggcaacg
     3661 cttggcagca ttgattcaac aacctttatg ggattgctgg ctaatcatgc tggattaaac
     3721 gggctgttac aggcgttacg cgaaatggtg gcctctccgc atgttgagct ggcagtgcat
     3781 ttatttgctg atttagccct cgccacgtca tttctcggcg ttgcgttagg cttatttgat
     3841 tatctggctg atttatttca gcgttcaaat accgttggtg gacggttgca aactggtgca
     3901 attacctttc tgccgccgtt ggcgtttgca ctgttttatc cacgaggatt tgtgatggcg
     3961 ctgggttacg ccggtgtggc gctggcggta ctggcattga ttatcccttc gctgttgacc
     4021 tggcaaagca gaaagcacaa tcctcaggcg ggttaccggg tgaaaggtgg tcgtccggcg
     4081 ctggtggtgg tgtttctctg tggtattgct gtgattggcg tgcaattttt gattgcggca
     4141 gggttgttac cagaagtggg gtgatcagat agcctcaaat tccttattgg gtgccagaat
     4201 taacgctgac acccaatttg acctcttaat gcaggcagca ctgcttaaat ttcttaccac
     4261 taccgcacgg gcaaggatcg ttacgccccg gtttctcttc tgctttgatc ggttgctgaa
     4321 cagctttttc ctgcggatgc gccatccagt acgcatgtag atcaagcgcc gccagtcgaa
     4381 tggcatctac gctctcttca aacgcttctg gcgacatttt ctctacccgc tcgaagtttt
     4441 cctcagtacc gtgcagcgca atcgcctcca gcgctggttt taacgaatcg ggcaacgttg
     4501 accagtcaga aagtgccacg ccccgcatat agccaaagca ccactcctca acaatcgtca
     4561 gctcgctgcc atcaacttct cgcaagccga ataacggctc aaactgctcc gggaattcgt
     4621 ttagacgctc tgcggtatcg gccatatgtt gaaaagccag attcataaag cgcgtcatct
     4681 ctttctctga cgcccagcgc ggcacatagt cagccccacc ccacacggca accagccact
     4741 gttccggttc aatctcttgc ggagaactca acaccgccgt caataaaccg tccagctccg
     4801 ccacatcaag gatggcgtgg tcagtgttgt atttggtcag aatatcgtcc agccattcca
     4861 actcactttc gtttaacggt cccgttttca tacgcttttc cttgtggatc tcaactcgcc
     4921 agcacctatc ttacatgccg gtccgtatca gagatacttt ttgagtggct ttgccggtga
     4981 ttaaaaatta aggagggtgt aacgacaagt tgcaggcaca aaaaaatcac ccgaaggtgg
     5041 tttcacgaca ctgcttattg ctttgatttt attcttatct ttcccatggt acccggagcg
     5101 ggacttgaac ccgcacagcg cgaacgccga gggattttaa attctacgca ggatcaatga
     5161 gttacatagc agtgcattgc gaaactttgc tgtaattgtt tactcatttt actgtaattg
     5221 gcagtaaata gatagacttg gataactttg agcacagaat ctgcacaggt aagtcccctc
     5281 tcacggaggc ctacctgtgc tatatctata tgactgcaaa gttacgagtt tgactggaaa
     5341 tcttcaatta tcttctgatt gtaatcatcc agatactttt gcagttcatc cctgtcgatc
     5401 agacgtacca aggctgattc agctaactct ttcgcagagc gagtgaagta ggaattagtc
     5461 acaaccatcg cctcatcaca accatagaat gttttagcag agatcacctg ctgcaccgcc
     5521 gagttaccta cagaaccaga ataatttttc gcctgaataa ccatatcctt accaaatcga
     5581 gtgacgaaga gatctgcccc ctgatcttgc gttctcttgg tttctttgac gtcatagccc
     5641 atagtctgga atacttccac aaggaaatct tcaaactgga aaccgtccat tgcatcaact
     5701 aaatacatgg tgacgaattt gttagggtta aaatgttcga gccgtgtagc taatctatca
     5761 accagaatat caaaataaat atgttcgcac acagctaagt attttttaac ttcatcaaat
     5821 gaaactaaag gaacaccagg cgtagcctcc gctttttcat tgaactctac tgatgagaac
     5881 tctattttat tgctccatat atagaataga aacaatgaaa gatctgccct aaaagtggta
     5941 cccgcttcct caatccatga cttcaaggat tcagtaagtg tagatttaat atgccgttta
     6001 acttccttag cgaaaccata ataaagagcg ttaaatgacg tggtaaggag taatttatct
     6061 aatagctcag gtaactcttc aagctcattg aacccttttc tgaccaacac ctcacggaaa
     6121 agttgtaatt cggagtatgt accattatct gttgagtaat ctgcttccga tttattatta
     6181 tgtgagaatc tggaagtgta aatgaagtta gtaaaatatg gatcttttaa actggagtat
     6241 ttttcgagaa cattttcaag caattgatta agctgagctt gctctttctt tttcccaaat
     6301 agatctttta gaacaccctt tgaacgatac tgaaactctg gataaaacga tggattcaat
     6361 ggtgtcatac gttgtatatc tattgcttgt gaggtcgatg atgctgaacc ccatgcagac
     6421 gtttttacag gcgaaactcc actacaccag ggacaattaa cctcaaaagt cgttctactg
     6481 caagtatcac actgataaat catttgaata ttctcctttt attctaatat ctgtctattc
     6541 ggcgcttcaa ttaccagcct aataatccac aatttaaaaa agatcgtcat cactcagtca
     6601 tattacttta tgttcttatt tttgagtcca tccacttagt catatcctta agaagaacca
     6661 gtgcatcttt tttgcttctc gtattccccc aaaaactcag ttcaagcact ttccccttcc
     6721 cagtaattga tacttcatag tcctcagggc tagctgttgg aatgaaatct ccagcactta
     6781 aagcaactct tatttcttct tttagtgcat taacttcagg gtaatcatct gaatgtatcc
     6841 atccatatac atagaactca gcttcatctc gaccatcctc tgaagggcga taaactaacg
     6901 taattcctgt tttaccttgc ccccagcatc ccggcatcag atgaattgct ttatagtaac
     6961 ccttccagtt attaatacct gttgcaatat gaatatcagg caatacctct gagacaaccg
     7021 atttagcttc ctcggtgata gcattttggt acatttccag caattgaacc gattttatca
     7081 aagctgtgaa attttcagtg acaaactcca catttttatc agatacctta tccatactaa
     7141 cctcactcaa ttttttaaga tgacttaaaa actcctgata aaaaaaagtc cacttgctga
     7201 actcttgatt catcatctct aaccccagac gtcgaatggc ggtttccagc agcagtgaat
     7261 aattgatcag ttgccaaccg tctacgcctt tagcgctgtt accgtcaggc tttaatatac
     7321 agcgaaatag tttttgattg ttgccgccgt aactatcaat gagacttaca tagctgggaa
     7381 aaggattata tgtatcagcc agaactttat gctcaatacc tataatgaat tcatcatgtc
     7441 tgataagaat atcaatatat ttcccatctt ctgttcgggc ctctctcatt agctccagag
     7501 aagtgaaatc aatttcatca acatcgaggg aatcatccag gcaacatagc aatgctttga
     7561 gcaaccatgg cggcaccatt ttctgggctc ccataaacaa agccatcaaa tccgtagttg
     7621 gattttcgag atatccggaa ccacccaatt caaaaaaatt gaattcaaca tcatcctcaa
     7681 ccgaaacacc tttcagttgt tcaataaatt tgacaaaaaa cgtttcagaa cgcaattcaa
     7741 cctcctttta aaaatcatga tgccattaca gattaattaa caccctaact ttgctataaa
     7801 ttatggtccc aaatattctc acaaattatt ttatacaaag actgtcgttc atcgacatct
     7861 tgttttttaa atgaatcatg tggtttgaaa ggcaatccga atacatttct caactgattg
     7921 aaattagggt tattcatata tgccaatggg cataacgatt tagccaggag attctctttg
     7981 atgtaatgag gttgcttttg atcgtaacac aaatcaccat atgactggtt tgagcctcta
     8041 ggtaataaaa ccaaatcacc taagcgattt ctgtaattgt taaattcgtg ctcttgttca
     8101 aactcatcag agtaacgttc atatttatcg gcccaaatat gctcgacttc aaatggctta
     8161 ccgtgttctg gctgataata tgtaatgaag gttgtactca ttccggcttg ctgctcaacc
     8221 cacgcagtta tacgagaaag caaaaacttc acaaaacgat agttttgacc atggagacga
     8281 aactctttca ttcctgcaaa agtatctggc atttcggata acttcttaga taacaaatct
     8341 tttaattctt caatactttt accacgaatt tctttaacaa gactgtacat tgtgtaacga
     8401 atagaactgg cagagaattt tcggaaatta acagaacgac gaacaacaaa tgtttcaata
     8461 tagcgcgcca ccaggtttat tttggctatc acagcctcag gactgtcacc tacatttaat
     8521 ggagccaaca tcaaagggaa acttaaagta ggtgcaatac cccaatggtg gatataaaat
     8581 acatattcca gttggtgcgt taatgctctc tcagcattca gtatttgtgt ataggcattc
     8641 aaataaaaca aaaagttttt ttgtataaat cgttcgaatg tctcaccatt atctgggtcc
     8701 aatcccacct cctgaagatt atctctaacc cagctatgaa aacgcgtacc tattttttca
     8761 aagtcttcat tttttgaacc agctttaccc gggcgtattg tatcagcata ttgagcacgc
     8821 aaccatgact ggaaaaaacg ttggtcttca tctttatcat agttttttaa atccatcatc
     8881 gcttttttcc agagttcatt tgccttttgg cgtttatctc cctgatgaaa gcgtgaaagt
     8941 aaaaaacctt taagcatttc ggacggagta agattcaatc ctcggtcatt catagtctca
     9001 aagatggtat atgcgttttc atctgaatag gcaactatct caaccataat aacgttatac
     9061 ttaagccagt cgataaaaaa aggaaaagcc tgacctttta attcatcagg aaaagcatct
     9121 gtgatattct gatatctctc caccatgtta tgggttgact catcatcccc atcaactaaa
     9181 ctatagctac caaaattaaa caatgcttcc atgcaaggta ttctgtcttc aactactata
     9241 ttgaatgatt tgctgccacg taactcggag aaaatcattg attctatttt ctcttcatat
     9301 ttaagttctt tctgaaggtt atggaggtaa attagaaata aagttaatga agtcagtcgt
     9361 tgctgaccat caataatact ccgtttccca tctttactac tcacaacaaa tggtcctaag
     9421 taataattat tgtagttttc accctgctcc cgagaatcac cgacggtgta ttcattgaga
     9481 aacgcagatg ttaagtctgt aaccaactct tcaatatgtt tctcacccca
//
LOCUS       DACAOP010000134         9383 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.134, whole genome shotgun sequence.
ACCESSION   DACAOP010000134 DACAOP010000000
VERSION     DACAOP010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9383
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.134"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            40..1806
                     /gene="adeD"
                     /locus_tag="IT892_004017"
     CDS             40..1806
                     /gene="adeD"
                     /locus_tag="IT892_004017"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAP3137161.1"
                     /translation="MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLIN
                     GGEISGPIVIKGRYIAGVGAEYTDAPALQRIDARGATAVPGFIDAHLHIESSMMTPVT
                     FETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
                     VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGL
                     GGKELNAYITAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNS
                     PQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGL
                     LAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQP
                     VSASDFALQFTPGKRYRVIDVIHNELITHSHSSVYSENGFDRDDVSFIAVLERYGQRL
                     APACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNG
                     QVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPAL
                     KLTSQGLFDGEKFAFTTLEVTE"
     gene            complement(1852..3243)
                     /gene="uhpT"
                     /locus_tag="IT892_004018"
     CDS             complement(1852..3243)
                     /gene="uhpT"
                     /locus_tag="IT892_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HAP3137162.1"
                     /translation="MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYL
                     IRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFML
                     ILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
                     LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPE
                     SYGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRI
                     GIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSDLANGRRGLVACIAL
                     ALIIATLGVYQHASNEYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKG
                     TFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERK
                     IRREKKIQQLTVA"
     gene            complement(3381..4700)
                     /gene="uhpC"
                     /locus_tag="IT892_004019"
     CDS             complement(3381..4700)
                     /gene="uhpC"
                     /locus_tag="IT892_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418123.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter family glucose-6-phosphate
                     receptor UhpC"
                     /protein_id="HAP3137163.1"
                     /translation="MLPFLKAPADAPLMTDKYEIDARYRYWRRHILLTIWLGYALFYF
                     TRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGL
                     IATGIINILFGFSTSLWAFAVLWVLNAFFQGWGSPVCARLLTAWYSRTERGGWWALWN
                     TAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLCWRLRDRPQALGLPAVG
                     EWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLVYVVRAAINDWGNLY
                     MSETLGVDLVTANTAVTMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVG
                     SLWLMPFASYVMQATCFFTIGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLG
                     ASLAGWPLAKVLDTWHWSGFFVVISIAAGISALLLLPFLNAQTPREA"
     gene            complement(4710..6212)
                     /gene="uhpB"
                     /locus_tag="IT892_004020"
     CDS             complement(4710..6212)
                     /gene="uhpB"
                     /locus_tag="IT892_004020"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418124.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine-protein
                     kinase/phosphatase UhpB"
                     /protein_id="HAP3137164.1"
                     /translation="MKTLFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFP
                     FGLRLGLMLQCPRGYWPVLLGAEWLLIYWLTQAVGLTHFPLLMIGSLLTLLPVALISR
                     YRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWH
                     YLANNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALP
                     IIALAWHYGWQGALIATLMNAIALIASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRL
                     RELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLA
                     ADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRG
                     IVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIE
                     DDGSGLPPGSGQQGFGLTGMRERVTALGGTLHISCLHGTRVSVSLPQRYV"
     gene            complement(6212..6802)
                     /gene="uhpA"
                     /locus_tag="IT892_004021"
     CDS             complement(6212..6802)
                     /gene="uhpA"
                     /locus_tag="IT892_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator UhpA"
                     /protein_id="HAP3137165.1"
                     /translation="MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLP
                     GRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKR
                     CSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
                     ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW"
     gene            complement(6877..7167)
                     /gene="ilvN"
                     /locus_tag="IT892_004022"
     CDS             complement(6877..7167)
                     /gene="ilvN"
                     /locus_tag="IT892_004022"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HAP3137166.1"
                     /translation="MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPI
                     QDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ"
     gene            complement(7171..8859)
                     /gene="ilvB"
                     /locus_tag="IT892_004023"
     CDS             complement(7171..8859)
                     /gene="ilvB"
                     /locus_tag="IT892_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HAP3137167.1"
                     /translation="MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYD
                     ALSQSTQIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARLDS
                     IPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFRIAQS
                     GRPGPVWIDIPKDVQTAVFEIETQPAMAEKAAAPAFSEESIRDAAAMINAAKRPVLYL
                     GGGVINAPARVRELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGVRSTNYILQEA
                     DLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQL
                     IPLVEAQPRAEWHQLVADLQREFPCPIPKACDPLSHYGLINAVAACVDDNAIITTDVG
                     QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMN
                     IQEMATASENQLDVKIILMNNEALGLVHQQQSLFYEQGVFAATYPGKINFMQIAAGFG
                     LETCDLNNEADPQASLQEIINRPGPALIHVRIDAEEKVYPMVPPGAANTEMVGE"
     gene            complement(8965..9063)
                     /gene="ivbL"
                     /locus_tag="IT892_004024"
     CDS             complement(8965..9063)
                     /gene="ivbL"
                     /locus_tag="IT892_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilvB operon leader peptide IvbL"
                     /protein_id="HAP3137168.1"
                     /translation="MTTSMLNAKLLPTAPSAAVVVVRVVVVVGNAP"
BASE COUNT         2307 a         2661 c         2451 g         1964 t
ORIGIN      
        1 aaataataat caaattgata aaatcaaaat gagaaaaata tgaataattc tattaaccat
       61 aaatttcatc acattagccg ggctgaatac caggaattgt tagccgtttc ccgtggcgac
      121 gctgttgccg attatattat tgataatgtc tctattctcg acctgatcaa tggcggagaa
      181 atttccggcc caattgtgat taaaggacgt tacattgccg gtgttggcgc agaatacact
      241 gatgctccgg ctttgcagcg gattgatgct cgcggcgcaa cggcggtgcc agggtttatt
      301 gatgctcacc tgcatattga atccagcatg atgacgccgg tcacttttga aaccgctacc
      361 ctgccgcgcg gcctgacgac cgttatttgc gaccctcatg aaatcgtcaa cgtgatgggc
      421 gaagccggat tcgcctggtt tgcccgctgt gccgaacagg caaggcaaaa ccagtactta
      481 caggtcagct cttgcgtacc cgccctggaa ggctgcgatg ttaacggtgc cagttttacc
      541 cttgaacaga tgctcgcctg gcgggaccat ccgcaggtta ccggccttgc agaaatgatg
      601 gactaccctg gcgtaattag cgggcagaat gcgctgctcg ataaactgga tgcatttcgc
      661 cacctgacgc tggacggtca ctgcccgggt ttgggtggta aagaacttaa cgcctatatt
      721 actgcgggta ttgaaaactg ccacgaaagt tatcagctgg aagaaggacg ccggaaatta
      781 caactcggca tgtcgttgat gatccgcgaa gggtccgctg cccgcaatct caacgcgctg
      841 gcaccgttga tcaacgaatt taacagcccg caatgcatgc tctgtaccga tgaccgtaac
      901 ccgtgggaga tcgcccatga aggacacatc gatgccttaa ttcgccgcct gatcgaacaa
      961 cacaatgtgc cgctgcatgt ggcatatcgc gtcgccagct ggtcgacggc gcgccacttt
     1021 ggtctgaatc acctcggctt actggcaccc ggcaagcagg ccgatatcgt cctgttgagc
     1081 gatgcgcgta aggtcacggt gcagcaggta ctggtgaaag gcgagccgat tgatgcgcaa
     1141 accttacagg cggaagagtc ggcgagactg gcacaatccg ctccgccata tggcaacacc
     1201 attgcccgcc agccagtttc cgccagcgac tttgccctgc aatttacgcc cggaaaacgc
     1261 tatcgggtca ttgacgtcat ccataacgaa ttgattacgc actcccactc cagcgtctac
     1321 agcgaaaatg gttttgatcg cgatgatgtg agctttattg ccgtacttga gcgttacggg
     1381 caacggctgg ctccggcttg tggtttgctt ggcggctttg gactgaatga aggtgcgctg
     1441 gctgcgacgg tcagccatga cagccataat attgtggtga tcggtcgcag tgccgaagag
     1501 atggcgctgg cggtcaatca ggtgattcag gatggcggcg ggctgtgcgt ggtacgtaac
     1561 ggccaggtac aaagtcatct gccgttaccc attgccgggc tgatgagcac cgacacggcg
     1621 cagtcgctgg cggaacaaat tgacgccttg aaagccgccg cccgtgaatg cggtccgtta
     1681 cccgatgagc cgtttattca gatggcgttt ctttctctgc cagtgatccc cgcgctaaaa
     1741 ctaaccagtc aggggctatt tgatggcgag aagtttgcct tcactacgct ggaagtcacg
     1801 gaataataaa aaaagcccgg cgtcatgccg ggcaaaagtc accagttacg tttatgccac
     1861 tgtcaactgc tgaatttttt tctcgcggcg gattttgcgt tcttccatta ccgccactat
     1921 cgccatcagg cagatacaac caatcgcggc gatatccagc gcggcgaagg tgcctgccca
     1981 gccggtaagg ccgaataccg gcgtcccatc ggcaatcatt cccagaccta acttggcaaa
     2041 gctgtcacca atcaggtaag caaaggtgcc tttaatacca tcggcagcgc caatcgcttt
     2101 tttaggtaca aagccaacag cagccacacc aatcaacaat tgcgggccaa agaccaggaa
     2161 acccaacgca aagagagaag ccagatagat atattcgtta ctggcatgtt gatacacacc
     2221 gagcgtggcg ataatcagcg ccagcgcgat gcaggccacc aggccacggc gaccgttcgc
     2281 caggtcagag agccagcccc acagcagcgt accgaccagc gcaccagctt caaacagcgt
     2341 aaagccctga atcgccaccg ctttagagag tttcagttcc tggaacgcgt atacggttga
     2401 ccactggtcg ataccaatac gtaccacata gaggaaaatg ttggcgaagc acagcagcca
     2461 gatcactttg tttttcagca catactcaac aaagatctgc cacttggtca tatcggtaga
     2521 ttctgtctct ttgtcctctt cgctgatctc ctcgccgaac agttcttcag ctttgccgag
     2581 gccataagat tccggggagt cgctgccgta acgcaggccg ataaaaccga caatcagcgc
     2641 gataatcgac gggaagataa acatgccgat gacatggcca tcgaacaggt aatttgcccc
     2701 gaacagcgcc acacctgctg cgcctgcacc gccaaggttg tgagaaatat tccagaaacc
     2761 gaggaatgtc ccgcgtttac gacgcggcgt ccatttggtg atggtggagt aactgcacga
     2821 accgccggta ctctggaaaa agccgcttaa ggcgtagaag gcaatcatca ggaacaggct
     2881 aaccgagccg ctgcccatac tggcactgaa gcccagcata caaatagcag agaggatcag
     2941 catgaacggc aggaattgtt tggtgttttt gccgtcggcg tagtaggaaa ccagcgtttt
     3001 acccacgcca taagtgatgg agaaacccag gccgatcatc cccagctgcg tcatgctcaa
     3061 cccgtaggtc gaaatcatat cgttctgcgc gatgttaaag ttcttgcgaa tcaggtacat
     3121 cgtcaggtag ccgataaaga ccaccaggta ggattgcatg aacggtttga accacatttt
     3181 gcgccgcact tcgagcggaa ggtccagggt cggcttgcga acctggttta agaaagccag
     3241 catgggttac tcctgaaatg aatacctgcg tgaggcatgc attgtaaaaa tcagcagcaa
     3301 atcaggcctg agatagcgtc caggcaaaac ctggaaaatt tcttagtttt gccggatatg
     3361 aagtgaaaag gtgagatgca tcacgcttcg cgcggtgtct gggcgttcaa aaagggcagt
     3421 aacagcagtg cggaaatccc ggcggcgata gagataacca caaaaaatcc gctccagtgc
     3481 caggtatcga gtactttcgc cagcggccaa ccagcaagcg acgcccccag ataagcaaac
     3541 aagccgacaa accccgtcgc cgcccctgcc gcctctttgt gggaacactc tgccgccgcc
     3601 ataccgatta acatctgtgg gccaaagaca aaaaaaccaa tggtgaagaa gcaggttgcc
     3661 tgcatcacgt agctggcaaa tggcatcagc cacagggagc cgactgaaag caaaattccg
     3721 gcggcgaaaa tcaaattcat cggccctcgg ttgccgttaa acaatttgtc cgagccccaa
     3781 ccggctacca gcgcaccgat aaatccgccc agttcaaaca tcgtcactgc cgtattcgcc
     3841 gtgaccagat cgacgcccag tgtctcggac atatacaaat tgccccagtc gttgatcgcc
     3901 gcccggacca catagaccag cacatagcaa aacgaaagca gccagatata cggattcagc
     3961 aacacatatt tggtgaggat ctctttacgc gtcaaccctg ccccttcttg ttgttgagca
     4021 atttccagcg cgtcgtgtcg ccattcaccg accgccggta aacctaacgc ctgcgggcga
     4081 tcgcgtagcc gccagcagag aaaaatcccc acgactatcg ccatacaacc agcaatcatc
     4141 atcccggcac gccagccgta atgcagcgca gccgctgcca tcacaatggg aatgagtgcg
     4201 ccgccgacgt tatgcgccgt gttccataat gcccaccaac cgccgcgctc ggtacgtgaa
     4261 taccaggccg ttaacagacg cgcacacacc ggtgaacccc agccctggaa aaaggcgttc
     4321 agcacccaga gcacggcaaa cgcccatagc gacgtcgaga agccaaacag aatgttgata
     4381 atgcccgtgg cgataagccc tatccccata aaataacggg catttgagcg atcgctgaca
     4441 atgccggaga caaacttcga cacgccatag gtaatgtaaa acagggtcgc taacaggccg
     4501 atatcgctac ggctgagcac gccgttagca aggatttctg gtacggcggc gttaaaactt
     4561 ttccgcgtga agtaaaacag cgcgtaaccc agccagatgg tcagcagaat atgccgacgc
     4621 cagtagcgat agcgggcatc aatttcatat ttatcagtca ttaatggcgc atcggcaggc
     4681 gctttcagaa acggcaacat catcaaacct tagacatagc gttgaggtag agaaacgctg
     4741 acacgcgtgc cgtgcagaca ggaaatgtgt aatgtgccac ccagcgccgt tacgcgctcg
     4801 cgcattccgg tgaggccaaa accttgttgc ccggaacccg gcggcaaacc gctgccatcg
     4861 tcttcaataa ccagcatcaa ccgttcatcc tgctgccagc cttgcagggt gaccgcgctg
     4921 gcatcagcat gtttcacaat gttgttcagc ccttcctggc agacacgaaa cagcgtcacg
     4981 cgctggtttt cgcttaacgc tgattcatcg attcgccatt cgagatggct gacaataccg
     5041 cgcccttcca gctccatttc ccgcatcagt gagcggatgg cctgctccag ggtgagatca
     5101 tccaactggc gcggacgtaa ccgacccaac aaacggcgca ccgcgtcgta aacgcccagc
     5161 gatagttgtt cgatgagctg cccgctctgc ttcacgctgg cgttatctgc cgccagccgc
     5221 tgaacaatgc ccgcctgagt acgaatagca gtgatggtct gaccgatatc atcatgcagc
     5281 tcacgcgcca catcacggcg cacgctctct tcggtttcca gcaaccgttc agccagatgc
     5341 tgattgcgcg ccagttcctt ttgcagcgac tggttaagtt cacgcaaccg ctggatgcca
     5401 gcgccaagca acaaccctgt cagactttgc accagcagcg agagcaataa atccaccgga
     5461 tgatcgcgcc aggtttgact ggcgatcagc gcgatggcgt tcatcaacgt cgcaatcagc
     5521 gccccttgcc aaccatagtg ccaggccagc gcgataatcg gcagcgccag acagaatggc
     5581 gtaaagcgcg acagttcgtc cggcaatccc aactggagcc agagactgat aacaaacagc
     5641 agcaagtacc agaccagatg tcgcccgcgc cagttgattg gctgagaaac cagtgacgga
     5701 ccgagcggca gccaggtgtt attggcgaga tagtgccaga acaccagaca tatcggggcc
     5761 agcgtcaggc cgccagttaa agtcagcaac agcgcattcc acgactcttt gccgtgccaa
     5821 agccagggca gcgactgcaa caacgccgcc gccgttaacg ccgccccctg taacagcaag
     5881 gtgcgccagt cacgctgatg gcgatagcgc gagatcagcg ctacgggcag taacgtcagt
     5941 aaactaccga tcatcaataa cggaaaatgg gttaaaccga ccgcctgcgt tagccagtaa
     6001 atcagcagcc actccgcgcc cagcaatacg ggccagtatc cgcgcgggca ttgcagcatt
     6061 agccccagac gcagaccaaa cggaaataac agcaccgcca tatcagggcg ctcaaccaga
     6121 tgcaggctga tactccacag gcaaaaccat gcggcagaga agataaaaaa gcaggcaata
     6181 acggtaatta agcgggagaa caacgtcttc atcaccagcc atcaaacatg cggcgcgcca
     6241 gctctacgtc gttactgacg cccagttttt ccatcagatt ggcgcgatgg acgtgtaccg
     6301 ttttcggtga caagcccagt tcggcggcaa tctctttcac cgccattcct tgcgccagtt
     6361 tttccgccac ctggcgttca cgtttggtta gcgggtcctg acgaccggat gccagtttaa
     6421 tggcaatatc cggcgtcaga taacagccgc ccgtggcaac cgtatgcacc gcagcaatga
     6481 gttcatccgg gctacagcgt ttggaaagaa agccgcgtgc ccccgcgtta agcgcctgct
     6541 caaccagcgc aggactgtcg tgaacggaga gcataatcgt cgccatacct ttcggcagct
     6601 ggcttagcag ctccagaccg gagatatcgg gcatggagat atcgcaaata cacacctgca
     6661 caccgcgccc cggcagcccc gccagcgcct cgcgccccga accaaactcg gcaactacct
     6721 gcaaatcagg ttccagcccc agcagctgcg caaagccgga gcggacgatg aggtgatcgt
     6781 ctataagggc aacggtgatc atggtcttgt cctggcgggt aaaaaaatac gcgcttacct
     6841 taacgataag cgcgatgttg ttcaagcctt gagcggttac tgaaaaaaca ccgcgatctt
     6901 gttaaacatc gtcggatcgg actgattacg ctgcactttc acgacatctt ccagcttatc
     6961 gatttggctt atcatctgct ccagacgctg gtcgtcattg accagtagcc agatatggct
     7021 tttgtcgctg tcctgaatcg gcagacaaag aatgccttca acgttaaaag cgcggcgggc
     7081 aaaaaggcca caaacgtggg tcattacgcc cggatggttg cgaacggtga gctccagaat
     7141 tacgttgtca tgagttgtgt tttgcatggc ttattccccc accatttcag tattcgccgc
     7201 acctggcggc accatcgggt aaactttttc ttcggcatca atgcgcacat ggatcagcgc
     7261 cgggccaggg cgattgatga tttcctgcaa tgaagcctgc ggatcggctt cgttattcaa
     7321 atcacaggtt tcgaggccga atccggcggc aatctgcata aagttgattt tgcccggata
     7381 ggtggcggca aaaacgcctt gctcgtagaa cagactctgt tgctgatgca ccagccccag
     7441 cgcttcgttg ttcatcagaa tgattttgac atccagctga ttttcactgg cggtcgccat
     7501 ctcctgaata ttcatcatca ggctgccgtc gccggagaaa cacaacactt tgcgatccgg
     7561 gttcgccagc gcagcgccaa tcgccgcagg caggccaaaa cccatcgtgc ccagcccacc
     7621 ggaggtcagc cactggcgtg ggcgattgag cggataagct tgcgcggtcc acatctgatg
     7681 ctgaccaacg tcggtggtga taattgcatt gtcatcgaca caggcggcaa cggcgttgat
     7741 caggccgtaa tggcttaacg gatcgcacgc tttcgggatt ggacacggaa actcacgctg
     7801 caaatccgct accaactggt gccactctgc acgcggttgc gcttccacca gcgggatcaa
     7861 ctgcgccagc acgtcatcaa catccgcctg aatcgccacg tgcggctgct tgattttacc
     7921 cagctctgca cggtcgatat cgacatgaat gattttggca ttcggacaga actgctcggt
     7981 tttgccaatc gcccggtcat caaaacgcgc accgagcact atcaacaaat ccgcctcctg
     8041 caaaatatag ttggtgctgc gcacgccgtg catccccagc atacccagcg acaacggatg
     8101 cgcttttggc aacatgccca gcgccattaa agtcatggtg gtaggcagtt gcgctttctc
     8161 cgccagttca cgcacccgtg cgggcgcatt gatcacaccg ccgcccagat aaagcaccgg
     8221 gcgtttggca gcgttaatca tcgccgctgc gtcacgaatg ctttcttcgc taaaggcggg
     8281 ggcggcggct ttttctgcca tagcgggctg tgtttcaatc tcaaaaactg ccgtttgcac
     8341 atccttagga atgtctatcc acaccgggcc tgggcggcct gattgcgcaa tgcggaaggc
     8401 atcgctcatg acctgcggga gttcttcgat atgtctgacc agatagttgt gtttggtgat
     8461 ggggatagag atgccgtagg tgtccacttc ctggaaggcg tcggtgccga tcatcgaggc
     8521 gggaacctga ccagtgatgc aaatcagcgg gatggagtcc agccgcgcat cggcaatggc
     8581 ggtcaccagg ttagtcgcac ccggtccgct acaggccata cagaccgccg gtttaccgtc
     8641 ggtgcgcgcc attccctgag cgataaagcc cgcgccctgt tcatgacggg ccagaatatg
     8701 gcggatttgc gtgctttggc ttaaggcatc gtaaacaggc aggatagaac cgcccggaat
     8761 gcctgtcaca atcttaatgc cctgctgttc caggaaatga acgataaatt ctgcgccggt
     8821 aaagcgctta cgcgtcgatg ttgtgcccga acttgccatg ctccagtcct tttcttctgg
     8881 gccgactttc cgggaggtgc ttaaacgaaa aaccccgccc ggtttgcgcc ggcggggttt
     8941 tggaatcgtg tgttgttcca gtccctacgg cgcattgccg acgaccacca ccacacgcac
     9001 gacgaccact gcggcggatg gcgcagttgg tagtagtttt gcgttgagca tggaagtagt
     9061 cattggggac cttgttggtt ttgtgtttaa caatatttat acaagcacag ctttacaggg
     9121 gagacaatgg aaaatttttc agcaagggaa aattgagggg ttgatcacgt tttgtactga
     9181 attgcagata acaaaaaacc ccgccggagc gaggtttcgt cagtcgcctg cggctggtaa
     9241 ccgcaaagca cactgtatta tgtcaacact gaaagtatac gtgttccgcg cagaacgcgc
     9301 aatttcggca cgaattttga cgtatttagt gcatagttga gtatcgatca cagtttgcgt
     9361 tttgtccaaa tattactgtt tat
//
LOCUS       DACAOP010000135         9329 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.135, whole genome shotgun sequence.
ACCESSION   DACAOP010000135 DACAOP010000000
VERSION     DACAOP010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9329
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.135"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(194..952)
                     /locus_tag="IT892_004025"
     CDS             complement(194..952)
                     /locus_tag="IT892_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP3137169.1"
                     /translation="MSQILLQPANAMITLENVNKWYGQFHVLKNINLTVQPGERIVLC
                     GPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDIRNIERVRQEVGMVFQHFNLFPH
                     LTVLQNCTLAPIWVRKMPKKEAEDLAVHYLERVRIAEHAHKFPGQISGGQQQRVAIAR
                     SLCMKPKIMLFDEPTSALDPEMVKEVLDTMIGLAQSGMTMLCVTHEMGFARTVADRVI
                     FMDRGEIVEQAAPDEFFAHPKSERTRAFLSQVIH"
     gene            complement(960..2063)
                     /locus_tag="IT892_004026"
     CDS             complement(960..2063)
                     /locus_tag="IT892_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP3137170.1"
                     /translation="MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWL
                     MWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINL
                     ALLIGLVSIAPMFWKILPHRGRYIAAWAVIYPLIVWWLMYGGFFALERVETRQWGGLT
                     LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVML
                     PLFMAEGTSIDKLIRALVGVILFQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQ
                     GLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEG
                     YVFAALIYWIFCFSMSRYSQYLEKRFNTGRTPH"
     gene            complement(2073..3254)
                     /locus_tag="IT892_004027"
     CDS             complement(2073..3254)
                     /locus_tag="IT892_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP3137171.1"
                     /translation="MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTV
                     TNLNNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYGRIFIVGLLNTLLVSALCIVFA
                     SVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
                     FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWP
                     IAAVLIIGLPLLAQWLFGAALHWDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFI
                     AEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSS
                     LAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVE
                     R"
     gene            complement(3322..4347)
                     /locus_tag="IT892_004028"
     CDS             complement(3322..4347)
                     /locus_tag="IT892_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3137172.1"
                     /translation="MKKMMIATLAAASVLLAVANQAHAGATLDAVQKKGFVQCGISDG
                     LPGFSYADADGKFSGIDVDICRGVAAAVFGDDTKVKYTPLTAKERFTALQSGEVDLLS
                     RNTTWTSSRDAGMGMAFTGVTYYDGIGFLTHDKAGLKSAKELDGATVCIQAGTDTELN
                     VADYFKANNMKYTPVTFDRSDESAKALESGRCDTLASDQSQLYALRIKLSNPAEWIVL
                     PEVISKEPLGPVVRRGDDEWFSIVRWTLFAMLNAEEMGINSQNVDEKAANPATPDMAH
                     LLGKEGDYGKDLKLDNKWAYNIIKQVGNYSEIFERNVGSESPLKIKRGQNNLWNNGGI
                     QYAPPVR"
     gene            complement(4778..4999)
                     /locus_tag="IT892_004029"
     CDS             complement(4778..4999)
                     /locus_tag="IT892_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137173.1"
                     /translation="MKRLIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTT
                     QDNWETAGAIAGGAAAVAGLTMGIIALSK"
     gene            complement(5252..8356)
                     /gene="acrF"
                     /locus_tag="IT892_004030"
     CDS             complement(5252..8356)
                     /gene="acrF"
                     /locus_tag="IT892_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit AcrF"
                     /protein_id="HAP3137174.1"
                     /translation="MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVS
                     VSANYPGADAQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDI
                     AQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVAS
                     NVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ
                     LGGTPALPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYN
                     VIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQ
                     LSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLS
                     AVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK
                     GGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEE
                     DQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAG
                     MAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFE
                     LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGV
                     SLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMV
                     PFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGY
                     DWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLA
                     ATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLR
                     PILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR
                     CFKG"
     gene            complement(8368..>9329)
                     /gene="acrE"
                     /locus_tag="IT892_004031"
     CDS             complement(8368..>9329)
                     /gene="acrE"
                     /locus_tag="IT892_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrE"
                     /protein_id="HAP3137175.1"
                     /translation="VRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQANYDSAKGE
                     LAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKATVESARI
                     NLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQSSNDFMRLK
                     QSVEQGNLHKENATSNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLRAVFPNPQH
                     TLLPGMFVRARIDEGVQPDAILIPQQGVSRTPRGDATVLIVNDKSQVEARPVVASQAI
                     GDKWLISEGLKSGDQVIVSGLQKARPGEQVKATTDTPADTASK"
BASE COUNT         2454 a         2437 c         2250 g         2188 t
ORIGIN      
        1 cttttgtttt atctgttgtt tgtcggtgaa cactctcccg agtaggacaa atccgccggg
       61 agcggatttg aacgttgcga agcaacggcc cggagggtgg cgggcaggac gcccgccata
      121 aactgccaga catcaaatca agcgaaaggc catccgaaag gatggccttt ttgcttttcg
      181 aactaacatt caattaatgg attacctgcg ataaaaatgc cctcgtacgc tctgatttag
      241 gatgcgcaaa aaattcatca ggtgcagctt gctccactat ttccccacga tccataaaaa
      301 ttacccggtc agcgacggtt cgtgcaaacc ccatctcatg tgttacacac aacattgtca
      361 tacccgactg cgccagccca atcatcgtat ccagcacctc tttcaccatc tcaggatcga
      421 gcgccgacgt tggctcatca aacaacataa ttttcggctt catacacagc gaacgcgcaa
      481 tggcaacgcg ttgctgctga ccacctgaaa tctgtccggg aaacttatgc gcatgttcgg
      541 caattctcac ccgctctagg taatgcaccg ccagatcttc agcctctttc ttaggcatct
      601 tgcgtaccca aatcggtgcc agggtacagt tctgtaaaac ggtcagatga gggaagagat
      661 tgaaatgctg aaagaccatt cccacttcct gcctgacgcg ctcaatattg cggatatctt
      721 cattaagttc gatgccatct accacgatcc gtccctgttg atgttcttcc agatgattaa
      781 tacaacgaat ggttgtcgat ttaccggaac ctgaagggcc acacagaacg atccgttctc
      841 ccggttgcac ggttaaattt atatttttca aaacatggaa ttgtccatac catttattga
      901 cgttttccag cgtaatcatc gcgttagcag gttgcagtaa aatttggctc atagtgtcct
      961 caatgcggtg tacgcccggt gttaaaacgt ttttccagat actggctata gcgcgacatg
     1021 ctgaaacaga agatccagta gatcagcgcg gcgaaaacat acccttccgt cgacataccc
     1081 aaccaggcgg gatcaacggt tgcctgctga acgctactga aaagatcgaa caacccgata
     1141 atgatcacca ggctggtatc tttgaagagt gcgatgatgg tatttaccag cccaggaatt
     1201 accagcttca acgcctgtgg cagaataacc agcccctgag ttttccagta acccaacgcc
     1261 agcgactctg ccgcttcata ttgcccttta ggcagcgcct gtaatccacc tcgcacgact
     1321 tccgcaacat atgctgactg aaacaggatc acgccaacca gcgcgcggat caatttgtcg
     1381 atactggtgc cttctgccat aaacaacggc agcatgaccg aagacataaa cagaacggta
     1441 atcagcggca cgccgcgcca gaattcgata aaaatgaccg ataagatacg cacaatcggc
     1501 atatgggagc ggcgacctaa cgccagtaag atcccccacg gtagcgcccc cgcaatccca
     1561 actgatgcaa taattaaagt tagcgtcagc ccgccccatt gccgggtttc aacccgctca
     1621 agagcaaaaa aaccgccata catcagccac cagacaatca gtgggtaaat caccgcccag
     1681 gccgcaatat agcgaccgcg atgcgggagt attttccaga acattggtgc gatcgacaca
     1741 agcccaatca gtaatgcgag gttaattcgc cagcgttggt cgtgtgggta aagcccatac
     1801 ataaactgac caaatcgttc gtggatgaag acccaacagg caccggcttt tgtgcagtcg
     1861 gcacgcgttg agccaaccca gttagcctgc aaaaatgccc agttcagcaa cggtgggatc
     1921 agttcccaca tcaaccatat gcagccaata gtcagcaggc tattgctcca gctggagaac
     1981 agattttttc gcacccacac catcgcgcgg cttgagttat ggctcgccgg gcgcggggga
     2041 tgagacagca atacttttgt catcatgact ccttagcgtt caacgatcgc gatgcggcgg
     2101 ttatagatat tcatcagcag cgagatagtc aggctgataa tcagatagac cgacatggtc
     2161 atggctatcg tctcgatggc ttgccccgtc tgattcagca cggtgccggc aaacagcgaa
     2221 accatatcgg gatagccaat agcggcggca agagaggagt ttttgacgat gttgagatac
     2281 tggctggtta acggtggaat aatcacccgc aatgcctggg gaataatgac ctggcgtagc
     2341 gtaaccgggt tgggtaatcc cagtgaccga gccgcttcat gttgaccata aggcactgcc
     2401 tggatcccag cgcggataat ctcggcgata aatgcagatg tataaaccga aagtgccagc
     2461 gttaaggctg ccagttcagg aattaaaacc atcccgccgc ggaagttaaa gcctcgtagg
     2521 gctgggacat cccagtgtag tgctgcgcca aaaagccatt gcgccagtaa aggcaaacca
     2581 atgatcaaca ctgcggcgat cggccaggtg cggcgcagtt gtccggtctt tatctggtat
     2641 gttttattaa agcggaatag cccaacagaa aggactatag ccataacaac agccaggata
     2701 aacgcaataa atccgtctcc cagctgcggt gacggaatat aaagcccacg attgctcaaa
     2761 aaggccagat caaacgcgct cacagcctgg cgtggtccgg gcaaattgcg caacacggca
     2821 aagtaccaga agaagatttg cagcagcggg ggaatattac ggaagatctc aatataaatt
     2881 gtggaaagct ttcgtagcag ccagttatcc gaaagtctcg ccagaccgat aaagaagccc
     2941 aaaacagaag cgaacacaat acacaatgca gaaaccagta gcgtattgag taagccgaca
     3001 ataaaaatgc gtccgtaggt gtcgccctgc tggtaatcga tcaaatgctg gacaataccg
     3061 aagccagcgc cgcgatccag aaaggcaaaa cctgaagtaa tgccacgatt attgagattc
     3121 gttacagtgt tgtgaaataa ccaaccaaca atgccgacaa cagcaacaac ggcaaggatc
     3181 tggaataacc aggcgcgaac cgtagggttg gcaaaagaga gtgagccttt aacggttgag
     3241 cggcgatgag acatagaaac ctcggaaagc ataacgctga agagagcgcc gccgtagcga
     3301 cgctcgttac ctcacaccga cttaacgcac gggcggtgcg tactgaatac cgccgttatt
     3361 ccagagatta ttttgcccac gtttaatttt cagcgggctt tctgaaccta cgttacgctc
     3421 aaaaatttcc gagtagttac ccacctgttt gatgatgtta taggcccatt tattatccag
     3481 cttcagatcc ttgccgtaat cgccttcttt acccagcaga tgtgccatat caggcgttgc
     3541 tggattagcc gctttttcat cgacgttctg ggaattgatg cccatctctt cagcattcag
     3601 catggcgaaa agcgtccagc gtacaatcga gaaccattca tcatcgccac gacgaactac
     3661 cggaccaagc ggttcttttg agataacttc cggtaagaca atccattcag ctgggttgct
     3721 taatttgatg cgcagggcat acagttgtga ttgatccgag gccagcgtat cgcagcgacc
     3781 agattccagt gccttcgctg attcgtcaga gcgatcgaaa gtcaccggtg tgtacttcat
     3841 attgtttgcc ttgaagtagt cggcgacgtt gagttcggta tcagtacccg cctgaataca
     3901 gacggtagcg ccatccagtt ctttcgcgct ttttagcccc gctttatcgt gcgtcaggaa
     3961 gccaatgccg tcgtaataag tgacgccggt aaatgccatt cccatcccgg catcgcgaga
     4021 tgaagtccag gtcgtattac gggagagcaa atccacctcc cctgactgta aagcggtgaa
     4081 gcgttctttt gcagtgagcg gggtatattt cactttcgtg tcgtcaccaa atacagcagc
     4141 ggcaacacca cgacaaatat caacatcaat acctgaaaac ttaccgtcag catcggcata
     4201 agagaaccca ggtaatccat cactgatccc gcattgcaca aaaccttttt tctgaacggc
     4261 atcaagcgtc gcgccagcat gcgcctgatt tgcaacggca agcagcacgc tggcggcagc
     4321 cagtgtggct atcatcatct ttttcataat gcttcctgtg aggcgaaaat tatcgttata
     4381 ggacgtttgg gaaacgtctt ttacctgtct gtggccatcc tcttataagc aaaagtagtg
     4441 ccagcttttg cgcacgattt cgcgtcgcaa taagctgagt gtagacagga aataataaaa
     4501 acagcgcccc gcaatggtgc gaaaatgaaa catgcgccac attttggcgc aaaatattta
     4561 cgcgtgtttt actaagcaga ataatgattg ttagcgtgag tatatttctg gtgggaagtg
     4621 tgaaaattaa attgatgcgt tatttcgaaa gcagcgaaat aacgcgatgt aacatgctaa
     4681 atcagcaggg aattacccag cagaatatag caatatttta tcttatggag agatactgta
     4741 tcgttaaaaa gagcgcggaa ctccgcgccc tgttcagtta tttcgataga gcgatgatcc
     4801 ccatcgtcag gccagcaaca gcagctgccc cgccggcaat agccccagcc gtttcccagt
     4861 tatcctgagt cgtgcctttc atacaggtat tggtgtgaac cagacgaccc tgatcgtcat
     4921 aaaccggaac gcagggcgaa tcgtgagcac agcccgccag caatgcggtg agcaatgcca
     4981 caggaattaa tcttttcatg gtgttacctc agtaataaac gctaacgctt aataagttaa
     5041 ctctcttatt aacgagctga atgccatttt atcaccggag gttataaatc ttgcggaatg
     5101 aataatgaca aattatgtga attgtaaaag tagtgaaggg agcgggaact atagaaagct
     5161 tttaaagagt gagcagaaga atatcttatt aatttttatg ggtttcactg gaaataataa
     5221 aggcacccga aagcgccttt atgtttctga tttatccttt aaagcaacgg cggatcacca
     5281 caaagaacac cggtacgaag aagattgcca gcaacgttgc agagaccatt cctcccatta
     5341 ccccgatacc cacagcgttc tgcgcgccac tgccggcacc gttactgata gctagcggta
     5401 atacgccgag aataaaggcg agagaggtca tcaggatagg acgcagacgc atacgtactg
     5461 ccatcagtgt cgcttcaaca acacctttac cctctttctc catgagatct ttagcgaact
     5521 caacgatcaa aatagcgttt ttggccgaca agccaattgt cgttagcaag cccaccataa
     5581 agtagacgtc atttttttga ttaaagagtg tcgccgccag cagcacgccg acaatcccta
     5641 acggcactac caacataacc gagacaggaa ttgaccagct ttcatagagt gcagcaaggc
     5701 acaggaaaac aaccacaaag gaaattgcta ccagagcggg agcctggttt cccgataagc
     5761 gttcctgata cgacataccc gtccagtcat aaccaatgcc cgcaggtaat tttgacgcaa
     5821 ggttttccat caacgccatg gcatcgccgg aactggttcc tggcgcggct tccccctgaa
     5881 tctccattga cggcagaccg ttgtagcgtt ccagtcgcgg agagccatac acccaatgtg
     5941 aagtggtaaa ggccgagaat ggcaccattt cgccgttggc gctgcggaca taaagtttat
     6001 cgacatcttc tggcagcata cggaatttgg catccgcctg aacatacaac tttttcacgc
     6061 gaccacggtc gatgaagtcg ttaacgtaag tcccacccag cgccgttgaa atggtctgat
     6121 tgatgtcaga aagtgaaaca cctaatgcct gcgccttttc ctggtcaact tccagtttaa
     6181 actgcgcggt gtcttccagg ccattagggc gcacgctgac taagctggca ggatgttgcg
     6241 ccgccatacc aagcaactgg ttacgggcct gggttagggc atcgtgaccc agcccagcct
     6301 gatcaattaa ctcaaagtcg aaacccgttg ccgtgcccag ttcaacaatg gctggcatat
     6361 tgaatggaat gacaaaaccg tcgcggatct tgcccaattc cattttggca cgatggatta
     6421 ccgcttccgc actgttttcg tcaccattac gctcttccca cggtttcaga ctgacgaagg
     6481 ccataccggc gttttgtgcc tggccgctga agctaaagcc gttaaccgta aagacacttt
     6541 caacgttcgc tttctcgttc ttcagatagt aatccgtaac ttgatccaac actttttgcg
     6601 tccgctcttg cgtcgcgcca gcgggtaact gaatcatggt cagaaagaca ccctgatcct
     6661 cttcaggtaa gaaggaagac ggaagacgta aaaacaacac caccattcct gcaacaatca
     6721 gcgcatagat cagtaaatat cgtcctgtgg atccgaggat tttgccgacg ctgttggtgt
     6781 agtggttaac gctatgatcg aaggtggtat taaaccaacc gaagaaaccg cccttatttt
     6841 cgtgatgctc agcagagacg ggtttaagca gcgttgcaca taacgcaggg gtaagaatca
     6901 atgccaccag aacagaaagc gccattgccg aaacgatggt gatagagaac tggcgataaa
     6961 ttgccccagt agaaccgccg aagaatgcca tcggaataaa taccgctgac agcaccatcg
     7021 cgatacccac cagtgcgccc tgaatttgcg acatcgattt ttccgtcgct tcttttggcg
     7081 ggagcttatc ctccatcatc acgcgctcga cgttctccac caccactatc gcatcatcga
     7141 cgagcagccc gatggcaagc accatcccga acatcgttag tgtgttgatg gagtaaccaa
     7201 aagcggcgag gatggcaaac gtccctaaca acaccacggg taccgcaatg gtggggatca
     7261 gcgttgctcg catattctgc aagaacagat acatcaccag gaacaccagc ataatggctt
     7321 cgaacagcgt ttttaccact tcgtgaatag aaagctggac gaatggcgtg gtgtcataag
     7381 ggtagagaac cttcattccc tgcgggaaga atggctgtaa ttccgccagt tttgccttaa
     7441 tggctttcgc ggtatcgaga gcattcgcgc cggttgccag cttaatcccc aggcccgccg
     7501 ccggttttcc gttgatacga gcgataacgt tatagttttc accgccaagt tcaacccgtg
     7561 cgacatcttt caggcgtacc accgagccgt cactgtttac gcgcagggtc actttgccga
     7621 attcttccgg atttttaaac cgcgtctgag caataatcga ggcgttcaat tgttgccctg
     7681 gtaacgctgg cgttccgccc aactgtccgg cagcgatctg atcgttctgt accttcaact
     7741 ggttaatcac atcaaccggt gtcagtttat atttgtttag cagatcggca tccagccaga
     7801 tacgcatcgc atactgtgcg ccgaaaagct gtacgtcacc gacgccattc agacggctaa
     7861 gcgtatcttt aacgttagag gccacatagt ccgagatatc gtcctgtgtg gtgcctgggt
     7921 tatcagagac aaagcccgcc accatcaaat agctgctact ggacttttca acactgatcc
     7981 cctgctgctg aacctcctgc ggcagcaacg gcgtggcgag ctggagtttg ttctgcacct
     8041 gcacttgcgc gatatcagga tcggtcccgg actggaaggt aagggtaatt gtcacgctac
     8101 cggcggaatc gctggtggag gacatataca tcaggttatc gataccgttc atattctgtt
     8161 cgataacctg cgtcaccgta tcctgcacgg tctgcgcatc agcgcccgga tagtttgctg
     8221 aaacagaaac cgcaggcggt gcaattgttg gatactgagc gacgggcaat tgtaggatcg
     8281 ccagtgcgcc cgccatcatc agaataatgg ccagcaccca tgcaaatatc ggtcgtcgaa
     8341 taaaaaagtt tgccatgtca gattacctta cttcgatgca gtatctgcgg gggtatcggt
     8401 agtggcttta acctgctctc ccgggcgcgc tttttgcagg ccgctgacaa tgacttgatc
     8461 gccagatttc agtccttcac taatcaacca tttatcgcca atcgcctgac tggcaacgac
     8521 agggcgcgct tcaacctgac ttttatcgtt aacaatcagc acggttgcat caccacgcgg
     8581 tgtgcggcta acgccttgtt gcgggataag aatggcgtca ggttggacgc cttcatcaat
     8641 ccgtgcacgc acaaacatac ccggcaaaag cgtatgttgc gggttaggga agacagcacg
     8701 tagggttatg gagccggtgc tttcatcaac ggtcacatcg gagaattgca gcgtaccttt
     8761 caggggatag gtttgaccgt tttccatgac caactctacg ttgctggtgg cgttttcctt
     8821 atgcaaattt ccttgctcta cggattgctt cagcctcata aaatcgttgc tggattgggt
     8881 cacatcaacg tagataggat cgagctgctg gacagtcgcc agttcagtcg tttgcccatt
     8941 agtgacaaga gcgccttcgg tcacagtcga tttgccgata cgtccgctaa ttggcgcagt
     9001 gactttggta taagcaagat tgatgcgagc gctttcgact gtggcttttg cggcaatcac
     9061 ggcggcatcg gcctgacgag catcagcaat ggcctggtcg tactcctgct ggctgatgta
     9121 tttcgtaccc acgagcggaa cgtaacgttt taccgtcaaa tgcgcgatgg cggcggcggc
     9181 ttcacttttc gccagttcgc ctttcgcgct gtcataattt gcctgatagg tcgcgggatc
     9241 gatctggtac agggactggc ctgcttgcac atcgctgcct tcagtgaaat tgcgattcag
     9301 tacgatcccg ctaacctgtg ggcgaactt
//
LOCUS       DACAOP010000136         9225 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.136, whole genome shotgun sequence.
ACCESSION   DACAOP010000136 DACAOP010000000
VERSION     DACAOP010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9225
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.136"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(112..897)
                     /locus_tag="IT892_004032"
     CDS             complement(112..897)
                     /locus_tag="IT892_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137176.1"
                     /translation="MNSKKLCCICVLFSLLAGCASESSIDEKKKKAQVTQSNINKNTP
                     QQLTDKDLFGNETTLAVSEEDIQAALDGDEFRVPLNSPVILVQSGNRAPETIMQEEMR
                     KYYTVSTFSGIPDRQKPLTCNKNKDKNENEDVASAENMNWMQALRFVAAKGHQKAIIV
                     YQDMLQTGKYDSALKSTVWSDYKNDKLTDAISLRYLVRFTLVDVATGEWATWSPVNYE
                     YKVLPPLPDKNEASTTDMTEQQIMQLKQKTYKAMVKDLVNRYQ"
     gene            complement(1225..1301)
                     /locus_tag="IT892_004033"
     tRNA            complement(1225..1301)
                     /locus_tag="IT892_004033"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1265..1267),aa:Asp,seq:gtc)
     gene            complement(1434..2165)
                     /gene="dnaQ"
                     /locus_tag="IT892_004034"
     CDS             complement(1434..2165)
                     /gene="dnaQ"
                     /locus_tag="IT892_004034"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HAP3137177.1"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
                     DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRIVRQASKLRVVFAT
                     DEEIAAHEARLDLVQKKGGSCLWRA"
     gene            2230..2697
                     /gene="rnhA"
                     /locus_tag="IT892_004035"
     CDS             2230..2697
                     /gene="rnhA"
                     /locus_tag="IT892_004035"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HAP3137178.1"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     gene            complement(2694..3416)
                     /locus_tag="IT892_004036"
     CDS             complement(2694..3416)
                     /locus_tag="IT892_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414749.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP3137179.1"
                     /translation="MKPARVPQTVVAPDCWGDLPWGKLYRKALERQLNPWFTKMYGFH
                     LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPISFMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQCRKPQA"
     gene            3450..4205
                     /gene="gloB"
                     /locus_tag="IT892_004037"
     CDS             3450..4205
                     /gene="gloB"
                     /locus_tag="IT892_004037"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HAP3137180.1"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNW
                     QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTL
                     VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
                     TEDIDLINVINEETLLQQPEERFAWLRSKKDRF"
     gene            4277..5635
                     /gene="mltD"
                     /locus_tag="IT892_004038"
     CDS             4277..5635
                     /gene="mltD"
                     /locus_tag="IT892_004038"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase D"
                     /protein_id="HAP3137181.1"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
                     DS"
     gene            complement(5683..6306)
                     /locus_tag="IT892_004039"
     CDS             complement(5683..6306)
                     /locus_tag="IT892_004039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP3137182.1"
                     /translation="MSGLPQGRPTFGAAQNVSAVVAYDLSAHMLDVVAQAAEARQLKN
                     ITTRQGYAESLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSP
                     GHPVRDIWLQTVEALRDTSHVRNYASGEWLTLINEANLIVDNLITDKLPLEFSSWVAR
                     MRTPEALVDAIRIYQQSASTEVRTYFALQNDGFFTSDIIMVDAHKAA"
     gene            complement(6310..7110)
                     /locus_tag="IT892_004040"
     CDS             complement(6310..7110)
                     /locus_tag="IT892_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAP3137183.1"
                     /translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
                     RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     gene            7351..8265
                     /locus_tag="IT892_004041"
     CDS             7351..8265
                     /locus_tag="IT892_004041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3137184.1"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISRYGKPETIDDLKQHICLGFTEPASLNTWPIARSDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDKEIARGELVELMADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEHVKTAPGGAVREA"
     gene            complement(8262..9065)
                     /gene="dkgB"
                     /locus_tag="IT892_004042"
     CDS             complement(8262..9065)
                     /gene="dkgB"
                     /locus_tag="IT892_004042"
                     /EC_number="1.1.1.346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /protein_id="HAP3137185.1"
                     /translation="MAIPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAA
                     VGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPN
                     DEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
                     NRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRKNLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
BASE COUNT         2485 a         2171 c         2178 g         2391 t
ORIGIN      
        1 ttaactccgg attccatgtc ctttcttgca ctgtctttgt caagaaaaat ttcttatgca
       61 aagaattttg tattattgcc gccagaaatt cctggcggca gatataattt attattgata
      121 gcggttaacc aaatctttta ccatcgcttt ataggtcttt tgcttaagtt gcatgatttg
      181 ctgctctgtc atatcagtcg tactggcttc attcttgtcg ggcaatggtg gaagcacttt
      241 atattcataa ttcaccggcg accaggtagc ccactcacct gttgccacat ccaccagcgt
      301 gaaacgtacc aggtagcgca gggagatagc gtcagtgagt ttgtcatttt tatagtcgga
      361 ccatactgtt gatttcagcg cagagtcata ttttcctgtc tgcaacatat cctggtaaac
      421 aataatcgct ttctgatgtc cttttgcagc cacaaaacgc agtgcctgca tccagttcat
      481 attctcagca ctggcaacat cctcgttctc atttttatct ttgtttttgt tacaagtcag
      541 aggcttttgc ctgtccggga taccagagaa tgtggaaaca gtataatatt ttcgcatctc
      601 ctcctgcata atggtttccg gtgcgcggtt gccggattga acaagtatta caggagaatt
      661 aaggggaacg cggaactcat ctccatcaag cgcagcttga atatcctctt cggatacggc
      721 cagagtggtt tcattaccga ataaatcttt gtctgtcagt tgctggggag tgtttttatt
      781 aatattactt tgtgtgactt gagctttttt cttcttttca tcaatagaag attcagaggc
      841 acatcctgca agcagcgaga ataacacaca tatgcaacaa agcttttttg aattcataat
      901 tggacactcc ctcgcctgtc ataatgatta gaatatttag cattgataac ggactctaat
      961 tatatacctc acttaaataa taacaaacaa aatcaatttg aaatatacat tcatttaatc
     1021 aatataaatt tattctctag aaatatattt aagctgaatg gttcgatatc attattgaat
     1081 tttaatgaat gagacaacaa gcgagaatca cgcacctacg ccagagtaaa atcattgaac
     1141 agagaaatgg tggaattcaa atacaaaaaa accgcaaaat taaaaatctt gcggctctct
     1201 gaactcattt tcatgagtga atagtggcgg aacggacggg actcgaaccc gcgaccccct
     1261 gcgtgacagg caggtattct aaccgactga actaccgctc cgcgttgtgt tccgttggga
     1321 acgaggcgaa tattacggat tgcctcgacc ttcgtcaacg gtttttctca tcttttgaat
     1381 cgtttgctgc aaaaatcgcc caagtcgcta tttttagcgc ctttcacagg tatttatgct
     1441 cgccagaggc aacttccgcc tttcttctgc accagatcga gacgggcttc atgagctgca
     1501 atctcttcat ctgtcgcaaa aacaacgcgt aacttacttg cctgacgtac aatgcgctga
     1561 attgttgctt caccttgttg ctgttgtgtc tctccttcca tcgcaaaagc catcgacgtt
     1621 tgaccaccgg tcatcgccag atatacttcc gcaaggatct gggcatcgag taatgccccg
     1681 tgcagcgttc gtttactgtt atctatttcg tagcgagcac ataacgcatc gaggctgttg
     1741 cgcttaccgg gaaacatttt cctcgccacc gcaaggctat cggtgacctt acagaaagta
     1801 ttggtcttcg gaatatcgcg cttaagcaac gaaaactcgt agtccataaa gccgatatcg
     1861 aacgctgcgt tatggatcac caactccgcg ccgcgaatat agtccatgaa ctcatcggct
     1921 acttcggcaa acgtgggctt atcgagcaaa aattcatcgg caataccatg tacgccaaag
     1981 gcttccggat ccaccagccg atcgggtttg agataaacat ggaagttatt gcccgtcagg
     2041 cgacggttca ccacttcaac ggcaccaatc tcaatgatct tgtggccttc atagtgcgca
     2101 ccaatctggt tcataccggt ggtttcggta tcgagaacga tctggcgtgt aattgcagtg
     2161 ctcatagcgg tcatttatgt cagacttgtc gttttacagt tcgattcaat tacaggaagt
     2221 ctaccagaga tgcttaaaca ggtagaaatt ttcaccgatg gttcgtgtct gggcaatcca
     2281 ggacctgggg gttacggcgc tattttacgc tatcgcggac gcgagaaaac ctttagcgct
     2341 ggctacaccc gcaccaccaa caaccgtatg gagttgatgg ccgctattgt cgcgctggag
     2401 gcgttaaaag aacattgcga agtcattttg agtaccgaca gccagtatgt ccgccagggt
     2461 atcacccagt ggatccataa ctggaaaaaa cgtggctgga aaaccgcaga caaaaaacca
     2521 gtaaaaaatg tcgatctctg gcaacgtctt gatgctgcat tggggcagca tcaaatcaaa
     2581 tgggaatggg ttaaaggcca tgccggacac ccggaaaacg aacgctgtga tgaactggct
     2641 cgtgccgcgg cgatgaatcc cacactggaa gatacaggct accaagttga agtttaagcc
     2701 tgtggtttac gacattgccg ggtggctcca accgcctggc gaattcgtgg cttgttttta
     2761 ctctgtttca tcggatttag cgttaaagga atagtccgtt tccgggcaac aataagttgt
     2821 aagcaaccaa gcgcaggaat atgcgcattc aatagttttc ctccgtgttt gttccacggg
     2881 agaacgtgga aacggctggc gtgtagcact tcaaaattca acaaagagag ccagtccagc
     2941 tgccgcatca gagtaaacat ccggctgtta tagggcgagg ttttgcgcaa taccggcaca
     3001 agtttgcgta atcccataaa actgatggga ttgaagccac taatgaccag ccagccatca
     3061 tcaatcaata cccgatcggc ttcacgcaat aaacgatgcg gatcggtgca ccacggcaat
     3121 gtatgtgcca gtagacaaac atcaacggat ttatcggcaa aaggaagatg aagtgggtcc
     3181 gcctgtacct ggacgggcat tccttgcgca gaaacattca cttgatgaga aaccgcgcac
     3241 gcttcgcaat tgatttctgc gcttaaattg ccaatcttaa gcagatgaaa accatacatt
     3301 ttagtgaacc acgggttgag ctggcgctcc agcgccttgc gataaagctt tccccagggc
     3361 aaatcgcccc agcaatcagg agccacgaca gtttgaggga ctcttgccgg tttcatcaca
     3421 accttccgtt tcacactgag aggtaatcta tgaatcttaa cagtattccc gcctttgatg
     3481 acaattacat ctgggttttg aatgatgaag caggtcgctg cctgattgtc gatcccggag
     3541 acgcagagcc agtattaaac gccattgccg ccaataactg gcaaccggag gccatatttc
     3601 tcacccacca tcaccacgat cacgttggcg gcgtaaaaga actggtggaa aagtttccac
     3661 aaattgtggt gtatggtcca caagagacac aagataaggg aacaacacag gtagtcaaag
     3721 atggcgaaac tgccttcgtt ttggggcatg aatttagtgt aattgctacg ccgggtcaca
     3781 ctttaggaca tatctgttac ttcagtaaac cttatctatt ttgcggcgac acactgtttt
     3841 ctggtgggtg tggtcggttg tttgaaggga cagcatcaca aatgtatcaa tcacttaaaa
     3901 agttaagtgc gttacctgac gatacattgg tatgttgtgc tcatgaatat accttatcaa
     3961 atatgaagtt tgctttgagt attcttccgc acgatttgtc cataaatgat tattatcgta
     4021 aagttaagga gttacgggca aaaaatcaaa taacactacc cgtaattctg aaaaatgagc
     4081 ggcaaattaa tgttttttta agaacggaag atattgattt aattaatgta attaatgaag
     4141 aaacattatt gcaacaacct gaagagcgtt ttgcatggtt aaggtcaaag aaagataggt
     4201 tctgataaaa ctttcttgtc atcggctccg ttcgccgtta tgattggtcg tcttttaagc
     4261 aactattgac acacacatga aggcaaaagc gatattactc gcctctgtcc tgctcgtggg
     4321 ttgccagagt accggcaacg ttcaacagca cgcacagagc ctttctgcag ctggtcaagg
     4381 ggaagcagca aagtttacaa gtcaggcacg atggatggac gatgggacgt ctatcgcgcc
     4441 agatggtgac ttgtgggctt tcattggcga cgagctaaag atgggaattc cggaaaatga
     4501 ccggattcgc gaacagaaac agaaatattt acgcaataag agctatctcc acgatgtaac
     4561 tttacgggca gagccgtata tgtactggat agcagggcaa gttaaaaaac gtaacatgcc
     4621 tatggaactg gtactactac ccatagtgga gagcgctttt gatcctcacg caacgtctgg
     4681 cgccaatgcc gcaggcatct ggcagatcat tccgagcacg gggcgcaatt atggtttgaa
     4741 acagacccgc aattatgacg cgcgtcgcga tgttgttgct tcaacaactg ccgcgctgaa
     4801 tatgatgcag cgtctgaaca aaatgtttga cggcgactgg cttctgaccg tagcggctta
     4861 taacagcggc gaaggtcggg tcatgaaggc aattaaaacg aacaaagcgc gtgggaaatc
     4921 cacggacttc tggtcgttac cgttgccgca ggaaacgaag cagtacgtgc ctaaaatgct
     4981 ggcattgagt gatattctca aaaacagcaa gcgttatggc gtacgtctgc caacgaccga
     5041 tgaaagccgt gctctggcgc gtgtgcacct gagcagcccg gttgaaatgg cgaaggtagc
     5101 agatatggcg gggatttccg tcagcaagct gaagacattc aacgctggcg taaaaggctc
     5161 cacgctgggc gcaagtggcc cgcagtacgt gatggtgcca aagaagcatg cagatcaact
     5221 gcgtgaatct ctggcttcag gcgaaattgc tgctgtacag tcgacgctgg ttgccgacaa
     5281 tacgccgctt aacagccgtg tttacaccgt acgctctggc gacacgcttt caagtatcgc
     5341 ttcacgtctc ggcgtaagca ccaaagattt gcagcagtgg aacaaactgc gcggatctaa
     5401 gctgaagcca ggccaaagtt tgacgattgg tgcaggcagt agcgcacagc gactggcaaa
     5461 caacagcgat agcattacgt atcgtgtgcg caaaggcgat tcgctttcaa gcattgctaa
     5521 acgccacggc gtgaacatca aagatgtgat gcgctggaac agcgacactg cgaatctgca
     5581 accaggcgat aagctgacgt tgtttgtgaa aaacaacaac atgccagatt cctgacaaac
     5641 cagataataa aaaggcaccg attcccccgg tgcctttttt atttatgccg ctttatgtgc
     5701 atctaccatg atgatatcac tggtgaaaaa gccatcattc tgcaaggcaa aatacgttct
     5761 cacctctgtc gatgcgctct gttggtaaat gcgaatagcg tctactaacg cttctggcgt
     5821 acgcattctc gcgacccatg aagaaaattc cagcggtaac ttatctgtaa ttaaattatc
     5881 aactatcaga ttggcttcat tgattaacgt caaccactca ccgctggcgt agtttcgtac
     5941 gtgagaggta tcgcgtaatg cttctaccgt ctgtaaccag atgtcgcgca ctgggtgacc
     6001 cggagacatt acgtccatca caatcagcct accgccaggt ttcaatatcc tattcacttc
     6061 tcgcagtgct gcaccaacat catgccagtg atgggcagaa taacggctga taacaatatc
     6121 aaatgcgtta tcggcaaatg gcagactttc ggcatatccc tggcgggtgg tgatattttt
     6181 cagttgccgg gcttcggcag cttgtgccac gacatccagc atgtgggcag ataagtcata
     6241 cgccaccacc gcgctcacgt tttgcgcagc gccaaacgtt ggtctgccct gtggcagacc
     6301 tgacatacct tatttatcag gcttgccggg actgaattca acgagtagcg gattgtgatc
     6361 ggaagcgcgc gtaaccagta cagaagcttc actgacgttc agaccacggt agaaaacaaa
     6421 atcgagcggg cgaccaaacg cccgacggcg ctgatcatcg gtaaaacgca cctggcgcag
     6481 cgacatttcc cgcgcaaagc gatataacgc gttcatcctt ctacggctcc aggcattgaa
     6541 atctcccgcc ataatgaccg ggccgctgtg gtgagctatc tgatcgccaa taggaagtaa
     6601 ctgcttacta tagacatcca cgcccagact gaagttgacg gcgtgtatat taaccaccat
     6661 caacaggcgg gtgtcaggta atggatagac cgtcaccagt gccgacttcg ccagacgcaa
     6721 aatgggttct cgttcacgta acgggcagca atacactgga tgtgccgccg aaagggtcat
     6781 tacgccagaa ggatgttgtg gcagcacgaa agcgggtacc tgatcggcgg caagatagtt
     6841 agcggtcgca aactgtacta actctggcgt tgtctgcgct tcctgcaata acaccagatg
     6901 tgcatctttg ccgtagttct ttaataccga caaccattca gcgcgttgct gtttgtatat
     6961 gttccacacc aggatccgaa tacgctcttc ggtacttaac ggttccccag gtggtaatgc
     7021 ctggccgatg ctcgcaaaag accccggcgg taagatcctt tccgcaggtt gtccggcaac
     7081 atagcgcatg gcataggtgt tttttcgcac ttttgacttt gaaacctcta ttacgtcaac
     7141 ccttccgcac tcgggagggt tctactgtta tagggatttt agctcactct ttcaacgagc
     7201 aattgtatat tgttatgtaa gcaagtgctt acaccggtca gaattttgct cattatggag
     7261 aacattaaat cgcatgacat atcacgcatc ctgatggttt aatgacaaat aaattcaaaa
     7321 tatctcttct attttgcaac aggagcaaaa atgaaagcca cgtcggaaga actcgccatt
     7381 tttgtttcgg tcgtcgaaag cggcagcttt agccgggcag cggaacaatt agggcaagca
     7441 aactcagcgg taagccgggc ggtgaaaaag ctggagatga aacttggcgt tagcctgctt
     7501 aatcggacca cgcgacaact tagcctgacg gaagaaggcg agcgttattt tcgtcgcgta
     7561 cagtcaattt tgcaggagat ggcagcggca gaatcagaaa ttatggagac gcgtaataca
     7621 ccgcgtggac tgttacggat cgatgccgca actccagtgg tgctgcactt tctgatgccg
     7681 ttaattaagc ctttccgtga acgctatccg gaagtcactt tgtcgctagt ctcctccgaa
     7741 acgattatta atttgatcga aagaaaagtg gatgtcgcga tacgcgctgg tacgttaacg
     7801 gattccagct tacgtgccag gccgttattt aacagttatc gaaaaattat cgcctccccc
     7861 gattatattt cccgctacgg gaagccagaa acgatcgacg atttaaagca acatatttgc
     7921 ctgggattca ctgaacccgc ttccctcaat acctggccga tagcccgtag cgatggacaa
     7981 ttacatgagg tgaagtacgg tttgtcatcc aatagtgggg aaacactgaa acagctttgc
     8041 ctgagtggca acgggattgc gtgtttgtcc gactacatga tcgacaaaga aatcgctcgc
     8101 ggagaattgg tggagttaat ggcagataaa gtgttgccag tggaaatgcc attcagtgcc
     8161 gtctattaca gcgaccgtgc ggtaagtacg cgcatccggg cttttatcga tttccttagc
     8221 gagcatgtaa aaacagctcc cggaggagct gtcagagagg cttaatccca ttcaggagcc
     8281 agaccttccg ggctaaccag gcggtcgttg caatccagtg cggcgatcgc ttttttatct
     8341 tcggcatcaa gctgtaaatt ttgtgcctta agattacttt ccaggttttt acgtttagta
     8401 gaagaaggaa ttactgagta accttccccc atagcccacg ccagaatcac ttgtgccgga
     8461 gtcgcattgt gtttagctgc gatacgagca ataacctcat ctttcagggc cttaccatac
     8521 gccagcgtca tataggaagt aatatggatg ccgtgctgtt tagcccaggc aaccacttta
     8581 cggttttgca gataaggaga gagttcaatc tggttagtag cgatgttttc agcaccaaca
     8641 gcagcaatcg ctttttccat caacgggatc gtgaagttgg aaataccgat ctcacgcgtc
     8701 agcccttgtt ttttggcttc cagcagcgcc tgcataaact cttcaacaga gacttcatcg
     8761 tttggtgacg gccagtggat tagcgtcaga tcaacataat cggtacgcaa tttttgcagg
     8821 ctctctttca gacttgggat caatttgtct ttgctgagat tttcaatcca gattttagtg
     8881 gtgatgtaga gttcatgacg tggcacgcca ctttctgcaa tcgcctgacc tactgcggct
     8941 tcgttatcat agatttgtgc ggtatcaatt gcgcgataac caagttcaag cgccgttatc
     9001 acagatgaaa taacaacgtc gtctttcaga cggaaagtac ctaaaccaaa tgcagggata
     9061 gccataatat gcctctttta atgctatttt cgttaactga ggtgattatg ggcttcagac
     9121 tgttgaggaa aaagagcgta aaatgcagag gatttttgcg attctggcaa taatagatat
     9181 acagacgaaa aaaaacctcg agcgttaact cgaggcttct taata
//
LOCUS       DACAOP010000137         9214 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.137, whole genome shotgun sequence.
ACCESSION   DACAOP010000137 DACAOP010000000
VERSION     DACAOP010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9214
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.137"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(358..1458)
                     /gene="chaA"
                     /locus_tag="IT892_004043"
     CDS             complement(358..1458)
                     /gene="chaA"
                     /locus_tag="IT892_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-potassium/proton antiporter ChaA"
                     /protein_id="HAP3137186.1"
                     /translation="MSNAQEAVKTRHKETSLIFPVLALVVLFLWGSSQTLPVVIAINL
                     LALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLSVVILEVSLISALMATGDAAPTL
                     MRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
                     LPAANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFVYEHEDDSDDDDPHHGKPSAH
                     SSLWHAIWLIIHLIAVIAVTKMNASSLETLLDSMNAPVAFTGFLVALLILSPEGLGAL
                     KAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAFMTGNELQFALGAPEMVVMVASLV
                     LCHISFSTGRTNVLNGAAHLALFAAYLMTIFA"
     gene            1728..1958
                     /gene="chaB"
                     /locus_tag="IT892_004044"
     CDS             1728..1958
                     /gene="chaB"
                     /locus_tag="IT892_004044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation transport regulator ChaB"
                     /protein_id="HAP3137187.1"
                     /translation="MPYKTKSDLPESVKHVLPSHAQDIYKEAFNSAWDQYKDKEDRRD
                     DASREETAHKVAWAAVKHEYAKGDDDKWHKKS"
     gene            2116..2811
                     /locus_tag="IT892_004045"
     CDS             2116..2811
                     /locus_tag="IT892_004045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HAP3137188.1"
                     /translation="MITRDFLMNADCKTAFGAIEESLLWSAEQRAASLAATLACRPDE
                     GPVWIFGYGSLMWNPALEFTESCTGTLVGWHRAFCLRLTAGRGTAHQPGRMLALKEGG
                     RTTGVAYRLPEETLEQELTLLWKREMITGCYLPTWCQLDLDDGRTVNAIVFIMDPRHP
                     EYESDTRAQVIAPLIAAASGPLGTNAQYLFSLEQELIKLGMQDDGLNDLLVSVKKLLA
                     ENFPDGVLRPGFA"
     gene            complement(2855..3208)
                     /gene="ychN"
                     /locus_tag="IT892_004046"
     CDS             complement(2855..3208)
                     /gene="ychN"
                     /locus_tag="IT892_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/F sulfur relay family protein YchN"
                     /protein_id="HAP3137189.1"
                     /translation="MQKIVIVANGAPYGSESLFNSLRLAIALREQESNLDLRLFLMSD
                     AVTAGLRGQKPGEGYNIQQMLEILTAQNVPVKLCKTCTDGRGISTLPLIDGVEIGTLV
                     ELAQWTLSADKVLTF"
     gene            3393..4787
                     /gene="ychO"
                     /locus_tag="IT892_004047"
     CDS             3393..4787
                     /gene="ychO"
                     /locus_tag="IT892_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter invasin YchO"
                     /protein_id="HAP3137190.1"
                     /translation="MSRFVPRIIPFYLLLLVAGGTANAQSTFEQKAANPFDNNNDGLP
                     DLGMAPENHDGEKHFAEIVKDFGETSMNDNGLDTGEQAKAFALGKVRDALSQQVNQHV
                     ESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDNDRYLTWSQLGLTQQDNGLVSNV
                     GVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANFYQPFAAWHEQT
                     ATQEQRMARGYDLTARMRMPFYQHLNTSVSLEQYFGDRVDLFNSGTGYHNPVALSLGL
                     NYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKKQLSAGEVAESQSLRGSRY
                     DNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQIRSRYGIRQLIWQGDTQ
                     ILSLTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVVEDNQGQRVSSNEITLTLVE
                     PFDALSNDELRWEP"
     gene            complement(4788..5438)
                     /gene="narL"
                     /locus_tag="IT892_004048"
     CDS             complement(4788..5438)
                     /gene="narL"
                     /locus_tag="IT892_004048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HAP3137191.1"
                     /translation="MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQG
                     IELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRG
                     ADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRE
                     RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF"
     gene            complement(5431..7227)
                     /gene="narX"
                     /locus_tag="IT892_004049"
     CDS             complement(5431..7227)
                     /gene="narX"
                     /locus_tag="IT892_004049"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarX"
                     /protein_id="HAP3137192.1"
                     /translation="MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSA
                     HAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGL
                     QDYWRNELIPALMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMA
                     VFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNN
                     MSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQ
                     NLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRL
                     ADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERA
                     TIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLT
                     TFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALS
                     NALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGD
                     CRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE"
     gene            7566..8957
                     /gene="narK"
                     /locus_tag="IT892_004050"
     CDS             7566..8957
                     /gene="narK"
                     /locus_tag="IT892_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter NarK"
                     /protein_id="HAP3137193.1"
                     /translation="MSHSSAPERATGAVITDWRPEDPAFWQQRGQRIASRNLWISVPC
                     LLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGR
                     RWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPK
                     QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWI
                     WVPFLAIFTIAAWFGMNDLATSKASIKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAG
                     FAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGL
                     LFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSD
                     ERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACV
                     VITWAVYGRHSKK"
BASE COUNT         2244 a         2252 c         2364 g         2354 t
ORIGIN      
        1 tgtctggttt caagattagc ccccgttttg ttgtcaggtt ttacctctca acgtgcgggg
       61 gttttctctt tccagcaacc aatgccacca gggataaagc cccgcaacat tgcgcctcac
      121 cggataacgc cggcttggtg tggatactac gtcgcaattc atcttcactt catccctgaa
      181 atgtttgcaa tgaagagtac attccggctt ttcaacagct gttgcagtgg tttcgtgcag
      241 ggtgtggtac aggctcgcaa ttctgattaa cgacctgtcc aggtagtatg aagaaataca
      301 ataagcagga atttatatta tctcccccga ttaccgtcat cggaggagat ataactgtca
      361 ggcaaatatc gtcatcaaat aggcggcaaa cagtgccaga tgcgctgcgc cattgagcac
      421 gttagtacgt ccggtggaga aggagatatg gcacagcact aaagaggcca ccatcaccac
      481 catttctggc gcaccaagtg caaactgcaa ttcgttaccc gtcataaagg caattagcgt
      541 gacgacaggt acggtaagcg aaatggttgc taacactgaa ccaaagaaca gattcatcgc
      601 gcgctgaacc tggttgttca acactgcttt taatgcacct aaaccttccg gcgacagaat
      661 caacagtgcc accaggaagc cagtaaaggc gacaggggca ttcatgctgt cgagcaatgt
      721 ctccagcgag ctggcgttca ttttggtcac cgcaataacg gcaatcagat ggataatcaa
      781 ccagatagca tgccacaggc tgctatgggc agacggttta ccgtgatgcg ggtcgtcatc
      841 atcactgtca tcttcgtgct cgtagacaaa caaactttga tgcgttttgg tctggatcag
      901 caaaaatacg ccatacattg ccgcagaaat taatgctacc agtaacgcct gaccggttga
      961 aaaattcgcc gcaggcagag ccattggaaa taccagtacg attatcgcca gggggaacag
     1021 cgcaattaaa tactgcttga taccaaacag attcatatat tgggtggcaa acttacgacc
     1081 gcccaacaat aatgaaaagc caaccagccc accggtaaca atcataatga ttgaatagag
     1141 cgtatcacgc attagcgttg gcgcggcgtc gccggttgcc attaaagctg aaatcaaact
     1201 gacttcaaga ataaccactg aaaggctaag aataagcgaa ccgtaaggtt ctcccaggcg
     1261 atgggctaat acgtccgcat gacggacaac actaaaggcg ctacttaaaa taccaataag
     1321 cgcaagaaga ttgatggcaa tgaccactgg tagtgtctgg ctgcttcccc acaggaacag
     1381 cactaccagc gccagaaccg ggaaaataag cgaagtctcc ttgtggcggg tttttaccgc
     1441 ctcttgagca tttgacatta tggttatccc tttgcagatg aatttatcga aaatgtaaaa
     1501 aataggtagg aaaaataaca gaaagtgtct ggatatcggt aacattttac gaatttttac
     1561 cccgctgtcg attttttact cattggggca taaaaataag tattacgttt agacaatgtt
     1621 tgttttagcg tttcttaaga agagtctgac ctgaaaattc ttatgttttg gcaagagtag
     1681 atattgttga ccacacttaa tgttcaactt tgtaaaagga gtcaacgatg ccgtataaaa
     1741 cgaaaagcga tctgccggaa agcgtaaagc acgttctacc gtctcatgcc caggatatct
     1801 ataaagaagc gttcaacagc gcatgggatc aatataaaga taaagaagat cggcgtgatg
     1861 acgccagtcg cgaagaaacc gcgcataaag tggcctgggc tgctgtgaag catgaatatg
     1921 ccaaagggga tgatgataaa tggcataaaa aatcgtaaaa ccggtcgctt agttaaagct
     1981 attcgtgcgg tgttgccttg caagtggtcc gtggattgca tattgtcccg ttagtggttt
     2041 caaaatgagc agtaaaaatg tccggaagac accaaaaagt tgtcgcaggg aagtatgcag
     2101 tggcggaggt gtaaggtgat aacgcgtgat ttcttgatga atgccgattg taaaacggca
     2161 tttggtgcca ttgaagaatc actcttatgg tcagcagaac aacgggcggc ttcgctggcg
     2221 gcgacgctgg cttgtcgacc tgatgaggga ccggtgtgga tcttcggcta tggatcgttg
     2281 atgtggaatc cggcactgga gtttaccgaa tcgtgcaccg gtacactggt tggatggcat
     2341 cgcgcatttt gcctgcgcct gaccgccggg cgcgggactg cgcaccagcc gggacggatg
     2401 cttgcactga aagagggcgg acgcaccaca ggcgtcgcct atcgactgcc agaagagacg
     2461 ctggagcagg aactaaccct gttgtggaag cgagagatga ttaccggctg ttatctgcca
     2521 acctggtgtc agcttgatct tgatgatgga cgcacagtaa acgccattgt gtttattatg
     2581 gacccgcgac atccagaata tgaatctgat actcgcgctc aggtcatcgc gccgttgatt
     2641 gcggcggcga gcggtccgct gggaaccaac gcacaatacc tgttttcact ggaacaggag
     2701 cttatcaaac tgggaatgca ggacgatggg ctgaatgatt tgctggtatc ggtaaaaaaa
     2761 ctgctggcgg agaattttcc ggatggtgtg ttacgtccgg gattcgcctg agtaaacttc
     2821 ccgcatagtg gggcgtcaga cgccccctca aacattaaaa tgtgagcact ttatcggctg
     2881 acagcgtcca ttgcgccagt tccacaagag taccgatttc caccccatca atcagaggaa
     2941 gtgtactaat cccgcgcccg tcggtacagg ttttgcacaa tttcaccggt acattctgag
     3001 cggtaaggat ctccagcatt tgctgaatgt tgtagccttc ccctggtttt tgcccgcgca
     3061 acccggctgt gaccgcatca gacatgagga acagacgcag atccagattg ctctcctgct
     3121 ctcgtaacgc aatggccagc cgcaagctgt taaacaagga ttcgctcccg taaggtgcgc
     3181 cattggcaac gatcacgatt ttttgcatta tttactcctg tattcaggga attagacact
     3241 catcttctac cttactgctt ctgcagcgtc tgaccaatcg gtcacatttt taaggatttt
     3301 cctgaaagcg cgagaaaata cgacaaaagt tgccagtaat cgttattctt taaggctatg
     3361 gtttttcatt attaccggaa gttaccgacg ttttgagccg tttcgttcct cgcattatcc
     3421 cgttttattt actcttgctt gtagcaggcg gtacagctaa cgcacaatct accttcgagc
     3481 aaaaagcggc aaatcccttt gataataaca atgatggtct gccggattta ggcatggctc
     3541 ccgaaaatca tgatggggaa aaacactttg ctgaaattgt gaaagatttc ggcgaaacca
     3601 gtatgaatga taacgggctg gatactggcg agcaggcaaa agctttcgca ttgggaaaag
     3661 tccgcgacgc gcttagtcaa caggttaatc agcacgtaga gtcctggcta tcaccgtggg
     3721 gaaatgccag tgttgacgtc aaagtggata acgaaggaca tttcaccggc agtcgtggaa
     3781 gctggtttgt gccgttacaa gataatgatc gttatctcac ctggagccag cttggtctta
     3841 ctcagcagga taatgggttg gtgagcaatg tgggcgttgg gcaacgctgg gcgcgcggca
     3901 actggctggt gggttataac actttttatg acaacttgct ggacgaaaat cttcagcgag
     3961 cgggctttgg tgccgaagcg tggggcgaat atttgcgatt atcggcaaac ttttatcagc
     4021 cgtttgctgc atggcatgaa cagacagcca cgcaggaaca acggatggcg cgcgggtacg
     4081 acctgacagc tcggatgcgc atgccgttct atcaacacct caataccagt gtcagcctag
     4141 aacagtattt tggtgatcgt gttgatttgt ttaactctgg tacgggttat cacaatcccg
     4201 tcgcgttgag tctgggatta aattacaccc ctgtgccatt agtcactgtg acggcccagc
     4261 ataaacaggg tgaaagtggc gaaaatcaaa ataacctcgg gctgaatctt aattaccgct
     4321 ttggtgtacc gctcaaaaaa caactttctg cgggcgaggt tgccgaaagt cagtcgttac
     4381 gtggtagtcg ctatgacaat ccgcagcgaa ataatctacc gactcttgag taccgacagc
     4441 gaaaaacgtt aacggtgttt ctggcgacac cgccgtggga tctaaaacct ggcgaaacag
     4501 tgccgctgaa attacaaatc cgcagtcgtt acggtattcg gcaactgatt tggcagggcg
     4561 atacgcagat attaagtttg acgccgggcg cacaagccaa cagcgcggag ggctggacgc
     4621 tgatcatgcc tgactggcag aacggggaag gggcaagcaa tcactggcga ttgtctgtgg
     4681 tggtggaaga taaccagggg cagcgtgtct cctccaatga gatcacgcta acgcttgtcg
     4741 aaccgttcga tgcattgtca aacgacgaac tgcgctggga accgtaatca gaaaatgcgc
     4801 tcctgatgca cccataccgc tgcttccacg cgagacttga gcttcatttt cttcagcatg
     4861 tgcttgacgt gcacttttac tgtgctttcg gtgatatcca ggcggcgggc aatcatcttg
     4921 ttcggcaaac cctgggcaat cagcttgaga atatcgcgct cgcgtggggt taactggtta
     4981 acatcgcgct cagtagtggc acggttagcg cgcaagctgg cggccagaac aggcgttaat
     5041 gcttcgctta ataccatttc gccagcagct gcctgatgca atgctttcag cagatcttcc
     5101 ggttccatat cttttaacag atagccatcc gcgccgcgtt tcagtgcggt gaccacatct
     5161 tcttcatggt tagagacgct gaataccaca atgcgccctg agagggactt ttcgcgcagt
     5221 ttatccagcg tttccagacc gttcatgccg ggcatattga gatctaacag gatcagatcg
     5281 ggatcaagag actccgccag ttcaataccc tgttcgccat tactcgcttc gccaaccacg
     5341 gtgatatctg gtgccatact gataagctgt tttacgccag ttcgcagcat cgggtgatcg
     5401 tcaatcagca ggatagtagc cggttcctga ttactcatgg gtatctcctt ggacgtctgt
     5461 gaaagttttt tcgggaataa aggtgaccac cacttcggtg ccacctgatt cacgacggcg
     5521 gacgcggcaa tcgcctcgta aactttgcgc acgatcgcgc attattatca tgccgtagtg
     5581 attgctgcgg atggcatttt caggcacgcc gcagccgtta tcctggacgg tcagtttgac
     5641 ctgattatcg ttttgcgcca ccgtcaccac gacttcactc gcttgcgaat gtttgagggc
     5701 gttacttaat gcctcacggg caatttgcaa caagtggatt gcctgatgcg aaggcaccag
     5761 gcgaggcggc aattgataat ccagcttcac cgggaagcca aatttggcgc tgtactcttc
     5821 gcaactcgcc tccagcgccg gacgtaatcc aggctcggtg agctgcaagc ggaatgtggt
     5881 gagcaattca cgcaactgcg cccaggatgc attcagttcg ttacggatct gacttaacag
     5941 ttcgcggctg ctttctggca gcgcatcgcc ctgcatctgt aaacaactca cctgcatctt
     6001 catgcaagag agagattggg caatagaatc atgcagttcg cgcgcaatgg tggcacgctc
     6061 ttccatcacg atcaactgtt gctgacgttc ctgatggcga tccagcgcca gcgtggcggt
     6121 gagttgttca accagggtat ccaccagttg ttgttgatca tggctaagat gacgcccctg
     6181 cggcagggtc gccagcaaaa taccgtactg cgtatgagag tcagccagcc gccacttcag
     6241 ggtcgtgccg cgatcaccaa cgggtaatac gccgcgcggg cagagctggc agcctttatc
     6301 atcacaagtc atatctggct ggcaggtaaa ctcctgatga ttctcttcat catcagtgtc
     6361 atacacccgc aattcgatat cacgtagcag ggttaaattc tgtaagccgt tgagtacagg
     6421 tgacaggcgt tcacacagcg gggcgcggga atgcaaacgg cggttagcct gccataaaaa
     6481 agagaggatc tgatttttat gctccagccc ggcggttttc tcctgaaccc gctgctcaag
     6541 tacggcataa ctttcggcca gttctgcaga catattgttc aacgcagttc caagcatcgc
     6601 catttcgttg cgcccgctga tgtttgcgcg ttgggtaaaa tcgcgatgac tgacggcact
     6661 cgccattgcc agcagttgcc gccacggttg tagcagtcgc gcccgcaacc agataatagt
     6721 gaacaccagt aaaagtgcca taaataccgc cattacccga tggaccagta ccactgtctc
     6781 gatgcgcatt tccgtggtgc ggtcaaaacc agataccagt tgatcaagcc cggcaacaaa
     6841 ctggctgaca tccgctgaca ccgtttctcg gttttgtgca cgcatcagcg cagggatcag
     6901 ttcattacgc cagtaatctt gtaaaccctg taattgcgcc agttgtccgt ctcgttctgc
     6961 tgctcgagtc aactcggcgc taaatgccgt ttgttccatc tctttaatta agggcttgtc
     7021 tttctcgctt aatggcactg ccgccaacag acggtaactt tgcatgcgca gcgatcccgc
     7081 tttgttgatc gcatgggcgc tgccctgaac gccttgcacc agccagccag aaaccgccat
     7141 ccctgccagt ccaatagcag tagaaagcaa cacaataagc gcaacctgat taaccagggt
     7201 gagcggagag agacaacgtt taagcatgta aacctcttcc ttcaggcttt aaatgagcaa
     7261 taaccttaat gaatgtgacg atacattctg gaatggcagt attctcggct attggctgaa
     7321 gtatacccat acccggaaag agttactcct tatttgccgt gtggttagtc gctttacatc
     7381 ggtaagggta gggattttac agcaccgtga aaaatcacat aatttttatg aagtcactgt
     7441 actcactatg ggtaatgata aatatcaatg atagataaag ttatcttatc gtttgattta
     7501 catcaaattg cctttagcta cagacactaa ggtggcagac atcgaaacga gtatcagagg
     7561 tgtctatgag tcactcatcc gcccccgaaa gggctactgg agctgtcatt acagattggc
     7621 gaccggaaga tcctgcgttc tggcaacaac gcggtcaacg tattgccagc cgcaacctgt
     7681 ggatttccgt tccctgtctg ctgctggcgt tttgcgtatg gatgttgttc agcgctgttg
     7741 cggtgaacct accgaaagtc ggctttaatt ttacgaccga tcagctattt atgttgactg
     7801 cgctgccttc ggtttctggc gcgttattac gtgttccata ctcctttatg gttcctatct
     7861 tcggtggtcg tcgctggacg gcgttcagca ccggtattct gattattcct tgcgtctggc
     7921 tgggttttgc cgtgcaggat acctccacgc cttatagcgt cttcatcatc atctctctgc
     7981 tatgcggctt tgctggcgcg aacttcgcat ccagtatggc aaacatcagc ttcttctttc
     8041 cgaaacagaa gcagggtggc gcgctgggtc tgaatggtgg tctgggaaac atgggcgtca
     8101 gcgtcatgca gttggttgct ccgctggtgg tatcactgtc gattttcgca gtatttggta
     8161 gccagggcgt caaacagccg gatgggactg agctgtatct ggcgaatgcg tcctggatat
     8221 gggtgccgtt ccttgccatc ttcaccattg cggcgtggtt tggcatgaac gatcttgcta
     8281 cctcgaaagc ctccatcaag gagcagttgc cggtactcaa acggggtcat ctgtggatta
     8341 tgagcctgct gtatctggca accttcggct ccttcatcgg cttctccgcg ggctttgcaa
     8401 tgctgtcaaa aacgcagttc ccggatgttc agattctgca atacgctttc ttcgggccgt
     8461 ttattggtgc gctggcgcgt tctgcaggtg gtgcattatc tgaccgtctg ggcggaactc
     8521 gtgtcacgct ggtgaacttt attctgatgg cgattttcag cggcctgctg ttcctgacct
     8581 taccgactga cgggcagggc ggaagcttca tggcgttctt cgcggtcttc ctggcgctgt
     8641 tcctgacagc tgggctgggt agtggttcca ctttccagat gatttcagtg atcttccgta
     8701 aactgacaat ggatcgcgtg aaagcagaag ggggttctga cgaacgtgcg atgcgtgaag
     8761 cggcaaccga cacggcggcg gcgctgggtt tcatctctgc gattggcgcg attggtggct
     8821 tctttatccc gaaagcgttt ggtagctcgc tggcattaac gggttcgcca gtcggcgcaa
     8881 tgaaggtatt tttgattttc tatatcgcct gcgtagtgat tacctgggcg gtatatggtc
     8941 ggcattctaa aaaataaacc gttactcgtc atacttcggg ttacatgtgc tgcggctgcg
     9001 ttcattcacc ccagtcactt actttagtaa gctcctggga ttcattcact tgccgccttc
     9061 ctgtaaaccg aattatatag agtaaaatat ttgattatcc tttgcgcggc atgatgtcgc
     9121 gcttttttta tgcgtcattt agttacaaca tactaatgtt atatggttta tttcgccgga
     9181 tttcattaag agccattaat atgttaccca tggg
//
LOCUS       DACAOP010000138         9145 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.138, whole genome shotgun sequence.
ACCESSION   DACAOP010000138 DACAOP010000000
VERSION     DACAOP010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9145
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.138"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..345
                     /locus_tag="IT892_004051"
     CDS             <1..345
                     /locus_tag="IT892_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP3137194.1"
                     /translation="MLNKGLESLAEGEKPLLHSDQGWHYRIKSYQSALADRGLVQSMS
                     RKGNCLDNAVMENFFGHLKEEMYYRRDYRNVEELENAVNEYITYWNQKRIKLSLGGLS
                     PVEYRTEHQKAG"
     gene            complement(445..1305)
                     /locus_tag="IT892_004052"
     CDS             complement(445..1305)
                     /locus_tag="IT892_004052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417249.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HAP3137195.1"
                     /translation="MNIAIVTINQENAATASWQAAQDFSGCTLAHWKIEPQPAVAEQV
                     LDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHW
                     GNALTATLQTEKRPLCLSLARQAGADKNATLPSGMQQLNIVPGALPDWLVSIENLKNV
                     TRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISG
                     HLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEA
                     LVTNIHAECQ"
     gene            complement(1302..2081)
                     /locus_tag="IT892_004053"
     CDS             complement(1302..2081)
                     /locus_tag="IT892_004053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HAP3137196.1"
                     /translation="MNILLAFKAEPDAGMLAEKEWQAAAQGNSGPDVSLLRSLLGADE
                     QAAAALLLAQRKNGTSMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPE
                     FVARHIAEWQYQNPLELIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDAPFI
                     TLEQRTENGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAVGKAAIIRKTVAAESPA
                     MQCLQLARAEQQRGATLIDGQTVAEKAQKLWQDYLRQRMQP"
     gene            complement(2059..3468)
                     /locus_tag="IT892_004054"
     CDS             complement(2059..3468)
                     /locus_tag="IT892_004054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3137197.1"
                     /translation="MTGRCLFGFSGEKPFLLPDNEGIKMNTSPVRMDDLPLNRFHCRI
                     AALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWIS
                     DHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFS
                     PRRHRGILLGAFSVVWTVGYVLASIAGHHFISESPEAWRWLLASAALPALLITLLRWG
                     TPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTLFSSRYWRRTAFN
                     SVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHR
                     KFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIR
                     SLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLAAVLLVGFVVTWLWAPETKA
                     LPLVAAGNVGGANEHSVSV"
     gene            complement(3490..4944)
                     /locus_tag="IT892_004055"
     CDS             complement(3490..4944)
                     /locus_tag="IT892_004055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAP3137198.1"
                     /translation="MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHG
                     IYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDG
                     SAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRS
                     IGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITE
                     VTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHF
                     ADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVA
                     AERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQ
                     NGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWS
                     KLEHGSAWTLLEGLKKQFDPNGIMNTGTIYPIEK"
     gene            complement(5014..5799)
                     /locus_tag="IT892_004056"
     CDS             complement(5014..5799)
                     /locus_tag="IT892_004056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417254.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP3137199.1"
                     /translation="MSIESLNALSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGAN
                     IFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILINNA
                     GICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
                     QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVL
                     DHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR"
     gene            6118..7395
                     /locus_tag="IT892_004057"
     CDS             6118..7395
                     /locus_tag="IT892_004057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3137200.1"
                     /translation="MQHNSYRRWIALAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSN
                     TEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVML
                     CIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFS
                     RFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVL
                     RISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPL
                     GGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYAS
                     RGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGYWQDTLPAAEAYRNMWL
                     MGMAALAMVIVFTFLLFQKIRTADSAPAMASSK"
     gene            7422..8900
                     /locus_tag="IT892_004058"
     CDS             7422..8900
                     /locus_tag="IT892_004058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAP3137201.1"
                     /translation="MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDAD
                     TAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLIS
                     WQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKTWAWSED
                     AAVMEKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAG
                     LLDDETAVISLGTYIALMMNGKLLPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSW
                     LRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMI
                     GFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFA
                     DVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFMPVESNAKRY
                     NAMNKGIFKELTKHTDVILKKSYEVMHGELGNADSIQSWSNA"
BASE COUNT         2306 a         2348 c         2244 g         2247 t
ORIGIN      
        1 atgttaaata aggggctgga aagccttgct gaaggggaga aaccgctgct ccacagtgat
       61 caaggatggc attaccggat aaaaagttat cagtccgccc tggcggacag agggttagtg
      121 cagagcatgt cgcgcaaggg caactgcctt gataatgcgg taatggagaa cttctttggt
      181 cacctgaaag aagaaatgta ctatcgccgg gactacagaa atgtagaaga gctggaaaat
      241 gccgttaacg aatacataac ttactggaat caaaaaagaa taaaactcag tcttggggga
      301 ctcagtccgg tagaataccg gactgagcat caaaaagccg gttaactgaa actgtccagg
      361 ttttggggtt cagttcattg acgcgtctta tcaggcttac aagtccccag cccgaaaccg
      421 taggcaggat catccggctg cacgttattg gcattctgcg tgaatgtttg tcaccagtgc
      481 ctccagcacc actttccagt catcaaccac gccaacatct gcctgtgaaa ataccgctgc
      541 gctggcgtca tgattaatcg ccaccacaaa cttgctattg cgtacgcccg ccattaacgc
      601 tgctgcgccg gaagcgccaa caacaataca cacctcaggt gccagcagat gtccagaaat
      661 accaatcact ttttcggcat caacgccacc gttcatcact cgtgcccgac tgtagcccac
      721 ttcggctccc agcttttctg ccagcatagc gatttcctgg ttatctgcct ctccgccctg
      781 ccccaccacc agcacccgtc tggcctcagc taatgggtcg cgggtaacat ttttcaggtt
      841 ttctatgcta accagccagt cgggaagcgc acctgggaca atgttcagtt gctgcatacc
      901 agagggcaac gtggcgtttt tatctgctcc cgcctgacgt gccagcgaaa ggcatagcgg
      961 gcgtttttct gtttgcagcg tcgccgttag cgcatttccc cagtgggatt tgcgcacgct
     1021 tacggttgga atatctaacg aagtcacctg gcagatgctt gcaccatgta aacgccaggc
     1081 cagccgggtc gacagttcat cgccaaacgt tcccggcgga aagagaacaa cgtccgctgg
     1141 cgttcgctgc cactgttcca ccagcgcatc cagcacctgt tccgccacag cgggctgagg
     1201 ttcaatcttc cagtgcgcca gggtacaacc gctgaaatcc tgcgccgcct gccagctcgc
     1261 tgttgcggca ttctcctgat ttattgtcac aattgcgata ttcatggctg catcctttgg
     1321 cgtaaatagt cctgccatag cttttgcgct ttttctgcta ccgtttgccc atcaatcagc
     1381 gtcgctccgc gttgttgctc tgctcttgcc agttgcagac actgcatcgc tggcgattcg
     1441 gcagcaacag ttttacggat aattgctgct ttccccaccg ccattcgctg acgcattccc
     1501 ggtactggca aggccacttc accgcactga cgcacggcaa tcaccgcagg caagcgaacc
     1561 cggcaacagc gcagcccgtt ttcagtacgc tgttcaaggg tgataaacgg cgcgtcgaga
     1621 gtaaaacgct ccacctgggt gaagcagggc cagcccagca tttccgccag caaaaatggc
     1681 gtttgcccat tctgcccttc gctgctttgg cagccagtaa ttatcagctc cagcggattc
     1741 tggtactgcc attcggcaat atggcgagcg acaaattccg gcgcaaagcg cagatctgcc
     1801 gccgtctcca gcaatacagc ttcctcaaac ccaagagcca taagatagcg cagccagtgc
     1861 aacgcccgtt catcccccat gctcaacgcg gttaaagaca tcgacgtacc gttttttctc
     1921 tgcgccaaca gcagcgcggc ggcagcctgt tcatcagcac cgagcaaact tcgcagaagc
     1981 gaaacatccg gtccgctatt accctgagcc gccgcctgcc actctttttc cgccagcatt
     2041 ccggcatccg gttcggcttt aaacgctaac agaatgttca ttcgcacctc caacatttcc
     2101 cgccgccacc agcgggagtg ctttggtttc tggtgcccat agccaggtca cgacaaaacc
     2161 aaccaacaac actgccgcca ggagcaataa ggtgacttgc attccccact gcgccagcac
     2221 ccacggcagc aggccagtac ttaccgccgc gcccaaccga ctcatggcgg tggcaaaacc
     2281 gacgcccagc gagcgaatgt cagtaggaaa actttccgca ggcaaaatgc ccaccagatt
     2341 actgactgcc gaaatggtgg tgctgaagag aacaaaaagc agcagcgtta atgaactgcc
     2401 ggaaggcaaa caagccatca ctaccagcgt tgccgccagc agcaaaaaac ttcccagcaa
     2461 aaatttgcga tgtgccagca ggtgcgtcag aactaatccc agcagcgcac ccacaattaa
     2521 caacgcatta agcatcaggc tagcggtcaa cgcatcttcc agaccaatag tctgggcgat
     2581 agttggcagc caggtataaa tcacaaacca tgggattacg aggcagacaa agaagacgct
     2641 gttaaacgct gtgcgccgcc agtagcgcga agagaacaag gttttgatgt gtttatgggt
     2701 cgccgttgcc acttcatcgc ccagtaaaac atggggacca aaatagcgat gcacgatagc
     2761 gtgagcttct gcaaaacgcc cctggcgcag tagccagcgt ggcgattctg gcgttcccca
     2821 gcgtaataac gtaatcaaca atgcgggcag agctgccgat gccagcagcc agcgccaggc
     2881 ctccgggctt tcgctaataa agtgatgtcc ggcaatactt gccagcacat agcctacagt
     2941 ccacaccacg ctgaacgcgc ccagcaaaat accgcggtgg cggcgcgggg aaaattcagc
     3001 cagcaaggtg tgaccgactg agtaatcgcc tcccagacca atgccaatca aaatgcgcag
     3061 tccaataaga tgctctggcg tggtggcaaa aaattgtaaa aacgaagcaa gcgtaatcag
     3121 caaaaagctg aaggtgaaga ttttttgtcg cccaatatgg tcggagatcc agcccagaac
     3181 caggctgcca agaaacaaac caaggagtgc tgagccgcca atcattcccg ccataaacgg
     3241 cgtcagttgc atggcgggcg taagctgaat aatggcgtaa ccaatgacgc cgaggacata
     3301 accgtcggtc aggtgtgcgc cgaaagtgag cgcagcaatg cggcagtgaa aacggttaag
     3361 tggtaaatca tccattcgca ccggtgaagt gttcatcttt atcccttcat tgtccggtaa
     3421 taagaacggc ttctcgcctg agaagccgaa aaggcaacgc cccgtcatcg cggaacgctg
     3481 cctgacacat tatttttcaa tcggatagat agtacccgta ttcataatgc cgttaggatc
     3541 gaactgcttt ttcagacctt ccagcaacgt ccacgcgctg ccgtgttcca gcttgctcca
     3601 gtgaacgcga tgtttaccaa tgccgtggtg gtgcaccatc gaaccaccga ggcgaatggt
     3661 ttcttcgcag atgattttgt tgagcggatt gtggtacttg tcgatttcct cttccggctt
     3721 acagtcaaca acgttgtagt cgtaaacgaa gtacatgttg gtgccgttct ggtagctgtg
     3781 agaggagtga ccgcccagca tggtgatgtc gtcggcgtgc gggaactcgg tacgaatacg
     3841 gttaataacg ctttcgtaga tttcgtgaat gcagctccag cagccggaca cttcggtggt
     3901 aaagcccatg ttgccggttt tgaggatctg cacacgttcg gcagctactt tatccggtcc
     3961 ccagttcagg ttgttaaacc aggtttcgat cagcttgctg tccactcgct ggcattgcgg
     4021 gtaacgtgcc acgatttcag caatcccttc gcccgtcgcc ttcgcaatgc gagggttacc
     4081 ttcagccata aagatcagca cgcattttcc gtcagcaaaa tgggtgaagt gttgggtgcc
     4141 atcttcagcg tcatacaaac gagcgatcga cggacgatac ccttccacca tgatttcacg
     4201 caggatgttg aagccggttt tcatgtcttc caggatatag ccgtagaaga ggttgttttc
     4261 cggggtgaac ttaaagattt tcacagttac ttcagtgata tagcacaatg caccttcgtt
     4321 gccgatgatg atgtgacgaa tgtccgggcc tgccgcgcgg cgtggtacgt ttttaatgcg
     4381 tgttacggtg ccatcagcca atactgcttc cagaccaacg accatatctt cgattgcgcc
     4441 gtagagtgtg gagaactgcc cgatactgcg ggttgctacc aggccgccca tctgcgccag
     4501 cggctttgac tgcggagaat gccccgtggt gtaacctttt tcacgcaacg cgttttccag
     4561 cacttccagc ggaactccgc attgcgccgt ggcctgcata ttctcaatat caatattaat
     4621 gatttgattc atggcagagc cgtcgagcac caccgagttt tccacaacgg tttccagccc
     4681 accttcggta gcggaagcac cggtacgcgg cacaccgtta attttgtgcg cattcataaa
     4741 attcagcaca cgggatactt gttctgtgga accgagtttt acgaccgctg ccggaatcgg
     4801 caaagtataa atgccatgaa tatccggaaa tttgcgaaaa cggtcaatac tgttcttctt
     4861 taatactgtt tcatcggtaa ttacgcgatc tgcaccaaca atttccttta gctggtcgac
     4921 aatcgctgcg cgagataaag acatagtaat tccttcctga taataaaaat ggaataatca
     4981 ttaataagag aaaacagaaa ccaccgttat ggattagcgc actaaataac caccatcaac
     5041 cactaataaa tgtccgttga cataattcga tgccggactt gcgaggaata cggctgcgcc
     5101 cattaaatcc tgagtatcgc cccaacggtt tgccggaata tgatcaagaa cgcgctgatt
     5161 ggtttctgga ttactgcgtg tcgccagcgt aatatctgtt gcataatagc caggggcaat
     5221 accatttacc tgaatattat attgacctag ttcatcacag taagctttgg tgaatccggc
     5281 aagagcatgt ttagtggcag aatatgcagg tgaccattgt ccacctaagt aagagaataa
     5341 tgaacagata ttaatgattt taccgctttt ctgcgggatc ataatttttg cagcttcata
     5401 gcttaactcg aatgcggcgg tcaggttcac atcaatcatc gggtcccagt cggcacgacc
     5461 gaagtccagc accttattca gcttacaaat accggcattg ttaatcagaa tatcgacggt
     5521 accgaaacgt tcgcaacagg cggcgattat cttctgcggc gctccttctg cggtgatatc
     5581 cacctgcatg aagtccacct caacaccctg tttttcaatc atttcctttg tttcgccgtt
     5641 atctttaacg aagcttggaa taaagatatt tgcgcctgct ttggccagcg ccatggcaaa
     5701 tgcctggcct aaaccgctat tcccgccggt aacaattgcg gttttacctt tcagggagaa
     5761 aaaatccatt gagagcgcat tgagagattc gattgacata gttagctcca atttccgtaa
     5821 ggcaaaaaaa aagaaaggta acttcccccg cgagagggaa gttacctttc tcattatctc
     5881 tggtaactgg agataatttt tatcataagg gcataatcgc taatgtgatc gtaatcacag
     5941 tgtgatattc gaattgtcaa ataattttaa aaagcagaag cgtgattact ctcacacaac
     6001 accactgctt tccatgttat ttcttattgc aattactaga gacctgagaa aagtaatcca
     6061 cctgaaaggg cggcttactt ttctcttttt tttgtctatt acaaatggga atacgatatg
     6121 caacacaact catatcgccg ttggatagcc ctcgcgataa ttagttttag cggcggcgtt
     6181 agtttcgacc tggcttattt acgttatatt tatcaaattc ccatggcgaa atttatggga
     6241 ttcagcaata ccgagatagg tttaataatg agtacatttg gtattgcggc cattattctt
     6301 tatgccccca gcggcgttat tgccgataaa ttttcacacc gcaaaatgat tacttccgcg
     6361 atgatcatta ccggattact gggtctgtta atggcaacat atccaccgct gtgggtaatg
     6421 ctctgtattc aggtcgcctt tgcgataacc actattttaa tgctgtggtc ggtgtcgatt
     6481 aaagccgcct cattgctggg cgatcatagc gagcaaggga aaattatggg ctggatggaa
     6541 gggctgcgcg gcgtcggtgt aatgtcgctg gcggtgttta ccatgtgggt cttttctcgc
     6601 ttcgctccgg atgacagcgc cagtctgaaa acggtcatca tcatctatag tgtggtttac
     6661 atcttgttgg ggattctgtg ctggtttttt gttagcgata acaacaatct gcgcagtgcc
     6721 aataacgaag aaaaacagtc attccagctt agcgacatcc tggccgtttt gcgcatcagc
     6781 accacctggt attgcagcat ggtgattttt ggcgtcttca ccatctacgc cattctgagt
     6841 tactccacca actatctgac cgaaatgtac ggcatgtcgc tggtggcggc gagctacatg
     6901 gggattgtga tcaacaaaat cttccgcgcg ctgtgcggcc cacttggcgg cattatcacc
     6961 acctacagca aagtgaaatc ccctacccgc gtgatccaaa tcctttccgt actcggcttg
     7021 ctggcgttaa ctgccctgct cgtcacgaac tctaacccgc aatcggtcgc gatggggatt
     7081 ggcctgattt tactgctggg attcacctgt tacgcctcac gcgggctgta ctgggcctgc
     7141 cctggcgaag cgagaacacc gtcttacatt atgggcacca cggtaggtat ttgttcggtg
     7201 attggattcc tgccggatgt cttcgtttac ccgattatcg gctactggca agacaccctg
     7261 cccgctgcag aagcctaccg caatatgtgg ctgatgggca tggcggcgct tgccatggtg
     7321 atcgtcttta cctttttgct gttccaaaaa attcgtactg ctgatagcgc ccctgctatg
     7381 gctagcagca agtaagtcca gaaaattaca ggagaaaaat catgtcgaaa aaatacatca
     7441 tagggattga tggtggaagt cagagcacaa aagtggtgat gtacgatctg gaaggtaatg
     7501 tggtttgcga aggcaaaggc ttattgcagc cgatgcacac gccagatgcc gataccgcag
     7561 aacatcctga cgacgattta tgggcatcat tatgctttgc cggtcacgat ttgatgagtc
     7621 agtttgccgg aaataaagaa gatattgtcg gtattggtct gggatccatc cgttgctgcc
     7681 gtgcgttatt gaaagccgat ggcacgccag ctgcgccgtt gattagctgg caggatgcac
     7741 gcgttacacg cccttacgaa catacgaatc ctgacgtggc atatgtcacc tctttttcgg
     7801 gttatctgac gcatcgctta accggcgagt ttaaagacaa tatcgccaac tattttggtc
     7861 agtggccggt ggattataag acctgggcat ggagtgaaga tgccgcagtc atggagaagt
     7921 ttaatatccc ccgtcatatg ctgtttgatg tgcaaatgcc gggcactgtt cttgggcata
     7981 tcactcctca agccgctctg gcgacacatt tcccggctgg gctgccggtt gtttgtacca
     8041 ccagtgataa accggtagaa gcactgggag ccgggttact ggatgatgaa actgcggtaa
     8101 tttctcttgg cacttacatc gcgttgatga tgaacggcaa attactaccg aaagatccgg
     8161 tagcgtactg gccgattatg tcttctattc cgcaaacctt gctgtatgaa ggttacggta
     8221 ttcgcaaagg catgtggacg gtgagctggc tacgcgacat gttaggcgag tcgttaattc
     8281 aggatgccaa agcacaggat ctttcaccgg aagatttgct caacaaaaaa gcgtcttgtg
     8341 tgccgccagg ctgtaatggt ctgatgacgg tgctggactg gctgaccaat ccgtgggaac
     8401 cgtacaaacg cgggattatg attggctttg attccagcat ggattacgca tggatatatc
     8461 gttcgatact ggaaagcgtg gcgctgacgc tgaagaacaa ttacgacaat atgtgtaatg
     8521 aaatgaatca ctttgcaaag catgtgatca ttactggcgg cggttcgaac agcgatctgt
     8581 ttatgcagat ttttgccgac gtgttcaacc ttccggcacg ccgtaacgcc attaatggtt
     8641 gtgcaagcct gggggcagcg attaatacgg cggtaggtct ggggctatac ccggattacg
     8701 caacggctgt cgacaaaatg gttcgcgtga aagatatctt tatgcctgtt gagagcaacg
     8761 ccaaacgcta caacgcgatg aataaaggca ttttcaagga gttaaccaaa catactgatg
     8821 taatcctgaa aaaatcgtat gaagtgatgc atggggaatt ggggaatgcg gattcgatcc
     8881 agagctggtc gaatgcgtaa gtgaggaaga ccgggcggga aactgcccgg cctgaacata
     8941 cctgaatggt tatccccgct ggcgcgggga acataagttc gacaacttaa aaaatgataa
     9001 caagtccggt ttatccccgc tgatgcaggg aacataataa aaactttaac tagttcggtt
     9061 tatccctgtt tttacaagga atattaacta cactcgatgt ctttagaata aaagacaata
     9121 cgaatcgcac tttatcaatt ttcac
//
LOCUS       DACAOP010000139         9119 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.139, whole genome shotgun sequence.
ACCESSION   DACAOP010000139 DACAOP010000000
VERSION     DACAOP010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9119
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.139"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..996)
                     /locus_tag="IT892_004059"
     CDS             complement(<1..996)
                     /locus_tag="IT892_004059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP3137202.1"
                     /translation="MKKRQKKPANMTASTPQKMEAFTFGVPSPVLDRRDILDYVECIN
                     NGKWYEPPVNFSGLAKSLRASVHHSSPIYVKRNILASTYIPHPLLSRQDFSRLVLDYL
                     VFANGYLEKRMSVTGQLLKLETSPAKYTRRGVEDGVYWYVSNYTQPHPFAPDSVFHLL
                     EPDINQELYGMPEYLSALNSAWLNESATLFRRKYYQNGAHAGYIMYVTDAAQSSTDVE
                     SLRNAMRDSKGLGNFKNLFFYAPNGKPDGIKIVPLSEVATKDDFFNIKKVSAEDLLSA
                     HRVPPQMMGIMPNNVGGFGDVVKAAQVFVRNELTPLQERFKELNNWLEMEVIRFKK"
     gene            complement(998..2767)
                     /locus_tag="IT892_004060"
     CDS             complement(998..2767)
                     /locus_tag="IT892_004060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase ATPase subunit family protein"
                     /protein_id="HAP3137203.1"
                     /translation="MTISTDLSLLHDPRRQARLLFWQGFSVPQIADTLQVKRPTVQSW
                     KQRDGWEETAPLNRVETTLEARLIQLYAKPDLTPHDFKVADFLSRQMERFARINRYGQ
                     TGNEVDLNPNIASRNKGDRKKPKRNYFSDEAIEKLEEIFFDQSFEYQLNWHKAGIAHR
                     IRHILKSRQIGATFYFARESLLRALKTGQNQIFLSASKTQAYVFRKYIIAFARMVDVD
                     LSGDPIVIGNNGAELIFLGTNSNTAQSHNGDLYVDEIFWIPNFQKLRKVASGMASQSH
                     LRTTYFSTPSTLAHGAYPFWSGELFNRGRSNASERVDIDISHKALAGGVLCPDGQWRQ
                     IVTIEDALAGGCTLFNLDQLKQENSADDFRNLFMCEFVDDKASVFPFEELQRCMVDAM
                     EEWEDFAPFSDRPFNWRPVWIGYDPSHTGDSAGCAVLAPPLVPGGKFRILERHQWKGM
                     DFATQAEAIRELTGKYCVEYIGIDATGIGQGVYQLVRSFFPAARAIRYTPEMKTAMVL
                     KAKDTIRRGCLEYDAGATDITQSFMAIRKTMTSSGRSSTYEASRSEEASHADIAWATM
                     HALLNEPLSAGSGMQSTSILDIN"
     gene            2934..3788
                     /locus_tag="IT892_004061"
     CDS             2934..3788
                     /locus_tag="IT892_004061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HAP3137204.1"
                     /translation="MAKKVSKWFRIGVEGDTCDGRVISGDDIQEMADSFDPRVYGCRI
                     NLEHLRGILPDSVLKRYGDVTEVKAEIISDDSALNGKKALFGKIAPLDELVSMVRSGQ
                     KVYTSMEIRPNFANSGKCYLVGLAVTDDPASLGTEYLEFCSRATQNPLAGKKAHPDDL
                     FSVATLAELEFEDVPDTVLNSLTDKVKAIFSRKQASDDGRLADVHEAVTTVTEQVQTS
                     LSNSEKRLTELETAFAQFKQDVTRQTEENAQAFTTLKSSLDNTESHRQPRREKSKGGM
                     GDELLTNC"
     gene            3849..4916
                     /locus_tag="IT892_004062"
     CDS             3849..4916
                     /locus_tag="IT892_004062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HAP3137205.1"
                     /translation="MRKDTRFKFNAYLSRVAELNGVDTDDVAKKFTVEPSVTQTLMTT
                     LQASSAFLTKVNIVPVDELKGEKVGVGVNGTIASTTDTAADDERKTADFTALESNKYE
                     CAQINFDFHIRYKQLDLWARFQDFQTRIRDAIIKRQSLDFIMAGFNGITRAATSSRKN
                     NPMLQDVAVGWLQKYRNEAAARVMSKITDEDGKVISDVIRVGKNGDYENLDALVMDAT
                     TNLIDEIYQDDPELVVITGRKLMADKYFPLVNKTQENSETLAADIIISQKRIGNLPAV
                     RVPYFPANALMVTRLDNLSIYFMDDAHRRAIIEEPKKDRIENYESMNIDYVIEAYAAG
                     CLIENINLGDFTAPAAPESGE"
     gene            4920..5675
                     /locus_tag="IT892_004063"
     CDS             4920..5675
                     /locus_tag="IT892_004063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase endonuclease subunit"
                     /protein_id="HAP3137206.1"
                     /translation="MTSPAARHMMRVSASETARRAAAPLRNATAYEQMLVKLAADCRT
                     LKQIRSNERKADKKRELLPFYLPWVGGVLSSGKGAQDDIVMTVMLWRLDADDIAGALE
                     IARYAMTYGLTMPTGGHRRTTPYLLAEEVALSAQRLLDAKQPVGLPLLLDTIALTERA
                     DMPDIVRAKLHKITGYVLREAGRLTDALTHLQRAIQLERAIGVKKDIEQLERALKPKA
                     EPAPKQNKPRTRKPAAKPAARRGRPPKAAKAAG"
     gene            5775..6281
                     /locus_tag="IT892_004064"
     CDS             5775..6281
                     /locus_tag="IT892_004064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HAP3137207.1"
                     /translation="MTTVIIEPKKEPQDVPGVVIPPPGVSEPVIKNTFFFPDVDPKRV
                     RELMRLEQTVSALRLNDAIKAGMAETNAELALWRVEQMAAGHDTLADVPADDIDGESV
                     RCFHYFRAVCAMTSATLFERYRGIDATAKGDRKAESTEAVIDELWRDMRWSVARIQDK
                     PRCIVGQI"
     gene            6281..6484
                     /locus_tag="IT892_004065"
     CDS             6281..6484
                     /locus_tag="IT892_004065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP3137208.1"
                     /translation="MKVRAMQGDTLDAICARYYGRTEGVVETVLWANPGLSELGVILP
                     HGTTIELPETDSAPKTETVNLWD"
     gene            6475..6696
                     /locus_tag="IT892_004066"
     CDS             6475..6696
                     /locus_tag="IT892_004066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein"
                     /protein_id="HAP3137209.1"
                     /translation="MGLSVEKITTFFAYWLAVGLAYFGAMSPEKLALYVGSACAIFTA
                     LTNYWFKRKTYRYLTSLGPDKGAARELNH"
     gene            6680..7189
                     /locus_tag="IT892_004067"
     CDS             6680..7189
                     /locus_tag="IT892_004067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HAP3137210.1"
                     /translation="MSSIIKRCSVAAVLALAALVPDFRLLNTSPEGLALIADLEGCRL
                     TPYQCSAGVWTSGIGHTAGVVPKGDITEQRAAENLIADVLNVEQRLAVCVPVDMPPRV
                     YNSLVSFAFNVGTGAACRSTLVSYIKRHQWWQACDQLTRWVYVNGTKNKGLENRRARE
                     RAYCVKGMQ"
     gene            7186..7611
                     /locus_tag="IT892_004068"
     CDS             7186..7611
                     /locus_tag="IT892_004068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006175794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysB family phage lysis regulatory protein"
                     /protein_id="HAP3137211.1"
                     /translation="MKVLMILLAGLLAMVLWLRHDNVNLSRSFEKASRVASEQKTTIG
                     MLKNQLAVSQRIASANEDAQVRLGDELAVAGEQAVKREETITRLMNENETLRRWYSDK
                     LPDAVRRLHIRTGCASAARCLQRLPEGESLPDAGKRPRQ"
     gene            7707..8174
                     /locus_tag="IT892_004069"
     CDS             7707..8174
                     /locus_tag="IT892_004069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001171050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP3137212.1"
                     /translation="MQKMKSLRKALNDAVPQILNNPEMMRIFADEGNIDARLADSLSH
                     EKNYTLNVIVCDFVGDPDLIFVPVAVWLRENQPDICTLDEGRKKGYRFQMDLNDGDNV
                     DISISLQLTERTLVRDENGALHVSYAPEPPLPEPVTRPTELYINGELVSKWDE"
     gene            8167..8613
                     /locus_tag="IT892_004070"
     CDS             8167..8613
                     /locus_tag="IT892_004070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016153626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HAP3137213.1"
                     /translation="MNEFKPFDDKLAGLIAAISPAGRRKLAAEIAKQLRRSQQQRIKQ
                     QKAPDGTPYQARKRQPLRAKKGRIKRTMFQKLRTNRYMKARGRDDAAVVEFTGKVQRI
                     AQIHQLGLKDRPNPHAQDVQYPERQLLGVDFGDNLLIEKLVIEHLN"
     gene            8749..>9119
                     /locus_tag="IT892_004071"
     CDS             8749..>9119
                     /locus_tag="IT892_004071"
                     /inference="COORDINATES: protein motif:HMM:NF015210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HAP3137214.1"
                     /translation="MSNDDKTLNLFPIDYPFETLCSRMKSNPIKLKLNPDFQRKYKWD
                     QDGWLRSSKFIESCLMRIPLPSCYFAEDDSGNHIVIDGVQRLTTIQKFFDDEFALEGM
                     TTFKELEGKKFSELGSLRSEL"
BASE COUNT         2121 a         2410 c         2597 g         1991 t
ORIGIN      
        1 ttttttaaat cttataactt ccatttctaa ccagttgttt agttctttga accgttcctg
       61 taaaggagtt aactcatttc ggacaaacac ttgtgcagct tttacaacat caccaaaacc
      121 gccaacattg ttaggcataa ttcccatcat ttgtggtggt accctatgag cactcaacaa
      181 atcttctgca ctaacctttt tgatattgaa aaaatcatct ttcgtggcga cttcactcaa
      241 cggcacaatc ttgatgccat ccggtttgcc gttgggcgcg tagaaaaaca agtttttgaa
      301 attcccgagt cctttcgagt cacgcatcgc gttgcggagc gactcgacgt cggtactgct
      361 ttgcgcggcg tcggtgacgt acatgatgta ccccgcgtgc gcgccgttct ggtaatactt
      421 gcggcgaaac agcgtagcgg actcattcag ccaggcagaa ttaagtgcgc tcaggtattc
      481 cggcatcccg tacaactcct gattgatatc gggctcaagc agatggaaaa cggaatcggg
      541 tgcgaacggg tgcggctggg tgtagttcga cacgtaccag taaacgccat cttcgacacc
      601 ccggcgggtg tatttagccg gtgaggtttc cagttttaag agctggccgg tgacgctcat
      661 gcgcttctca agatagccgt tggcaaagac cagataatcg agcaccaggc ggctgaagtc
      721 ctgacgtgac agcaacgggt gcggaatgta ggtgctcgcc agaatgttac gtttcacgta
      781 aatcggcgag ctgtgatgaa cggaggcgcg caggcttttt gccagccccg agaagttgac
      841 cggcggctcg taccatttcc cgttattgat acactctacg tagtcgagaa tgtcgcggcg
      901 atccagaacc ggggaaggca caccaaaggt gaacgcctcc attttttgcg gtgtgctggc
      961 ggtcatgttg gcgggtttct tctgtcgttt tttcatctta gttaatatcc agaattgagg
     1021 ttgattgcat gccgctaccg gcggaaagcg gttcgtttaa cagggcgtgc atggtcgccc
     1081 acgcaatatc cgcgtggctg gcctcttcgc tgcggctggc ctcataggtg gagctgcgcc
     1141 cgctgctggt catggtttta cggatagcca taaatgactg tgtgatgtcg gtcgcaccgg
     1201 cgtcatattc cagacatccg cgacggatgg tgtctttcgc tttcagcacc atcgcagttt
     1261 tcatttccgg cgtgtagcga atggcacgcg ccgccgggaa gaaggagcgc acgagctggt
     1321 aaaccccctg gccgatgccg gtcgcatcga tgccgatgta ctcgacgcaa tatttcccgg
     1381 tcagctcgcg gatagcctcg gcctgtgtcg caaaatccat ccctttccac tggtgacgct
     1441 caaggatgcg gaacttgcca ccgggaacca gtggtggagc cagtaccgca cagccagcgc
     1501 tgtcgccggt gtgcgacggg tcatagccaa tccagaccgg gcgccagtta aacggacggt
     1561 cagagaacgg cgcaaagtcc tcccattctt ccatcgcatc gaccatgcag cgctgtagct
     1621 cctcgaacgg gaataccgac gctttatcgt caacaaactc gcacatgaag aggttgcgaa
     1681 aatcgtcggc gctgttttcc tgtttcagct gatccagatt aaacagggtg catcccccgg
     1741 cgagtgcgtc ctcgatggtg acaatctgcc gccactggcc gtccgggcac agcacgccac
     1801 cggcgagcgc tttgtggctg atatcgatgt cgacgcgctc gctcgcgttg ctgcgtcccc
     1861 ggttaaacag ttcacctgac cagaacggat acgcgccatg tgccagcgtt gagggtgttg
     1921 aaaagtaggt ggtgcgcagg tgggactgcg acgccatccc cgaggcgact ttgcgcagct
     1981 tctgaaagtt ggggatccag aagatttcat cgacatacag gtcgccgtta tggctctgcg
     2041 cagtgtttga gtttgtcccg agaaaaatca gctctgcgcc gttgttgccg atgacaatcg
     2101 ggtctcctga caggtcgacg tcgaccatgc gcgcaaaggc gatgatgtac tttcggaaca
     2161 cgtaagcctg cgtcttactg gctgacaaaa atatctggtt ttgcccggtc ttaagcgcac
     2221 gcaggaggga ctcacgcgca aagtagaacg tcgcgccaat ctggcgtgat ttgaggatgt
     2281 ggcgaatacg gtgcgcgata ccggccttgt gccagttgag ctgatactca aaggactgat
     2341 cgaagaaaat ctcttccagc ttttcgatgg cctcgtcgct gaaataattg cgtttcggct
     2401 ttttgcgatc ccctttattg cggctcgcaa tgttggggtt taaatccact tcattaccgg
     2461 tctggccgta gcggttgatg cgtgcgaatc gctccatctg gcgtgacaga aaatcagcga
     2521 ccttgaagtc atgcggcgtc aggtcaggct ttgcataaag ctggatcagg cgcgcctcga
     2581 gcgtcgtttc cacgcgatta agcggggcgg tttcctccca cccgtcgcgc tgtttccagc
     2641 tctgcacggt cgggcgcttt acctgcagtg tgtcggcgat ttgtggtacg gaaaatccct
     2701 gccagaacaa cagccgcgcc tgtcgtcgcg ggtcatgcaa aagggagagg tcagtcgaaa
     2761 tggtcatggt tgcctcgtac tggtgaatac ggggcaaggc taaggaaata gccgggcatt
     2821 atcgctaacc ccctgttgtg tcaggggttg cacttccgca agcggtggct gatgcggggc
     2881 ggagtcggga aactaccccc gaaccgaaaa cccaatatca ggacacctga acaatggcaa
     2941 agaaagtttc taaatggttt cgcatcggcg tcgagggtga cacctgcgat ggccgtgtca
     3001 tcagcggtga tgacattcag gaaatggcgg attccttcga cccgcgcgtc tacggttgcc
     3061 gcatcaacct cgaacacctg cgcggcattc tgcccgacag tgtgctcaaa cgttatggcg
     3121 acgtgaccga agtgaaagcg gaaatcatca gcgatgactc tgccctgaat ggcaaaaagg
     3181 cgctgtttgg caaaatcgca ccgctggacg aactggtcag catggtgcgc agcggtcaga
     3241 aagtttacac ctcgatggag atccgcccta acttcgccaa cagcggcaaa tgttatctcg
     3301 ttggcctggc ggtgaccgat gacccggcaa gcctcggcac cgaatacctc gaattctgca
     3361 gccgtgcgac ccagaacccg ttggccggta aaaaagctca ccctgacgac ctgttttccg
     3421 ttgccacgct ggctgagctg gaattcgagg acgtccccga tactgtcctc aacagcctga
     3481 ccgacaaggt caaagccatt ttcagccgca agcaggcgag cgatgacggg cgtctggcag
     3541 atgtgcatga ggcggtcact acagtcactg agcaggtgca gaccagcctg agcaatagcg
     3601 aaaaacgttt aaccgaactc gaaaccgcat ttgcgcagtt taagcaggat gtgacccgcc
     3661 agaccgaaga aaacgcgcag gcgtttacca cgctgaaaag ttccctcgat aacaccgaaa
     3721 gccatcgcca gccgcgccgc gagaagtcga aaggcggaat gggcgacgag ctgctgacca
     3781 actgctgata acccgccggg tgcgcgtcac ccggcctgat gccccttttt agagaaacag
     3841 gaataacaat gcgtaaagat acccgcttta aatttaatgc ttacctgtcc cgcgtggcgg
     3901 aactgaacgg cgtcgacacc gacgatgtgg caaagaaatt caccgtcgag ccgtccgtga
     3961 cgcaaaccct gatgaccact ctgcaggcgt catccgcgtt tctgaccaaa gtgaatatcg
     4021 tgccggtcga cgagctgaaa ggcgaaaaag tcggggtggg cgtcaacggt acgattgcca
     4081 gcaccaccga tactgccgct gatgatgaac gtaagaccgc tgattttacc gcgctcgaat
     4141 ccaacaaata cgaatgcgcg caaatcaact tcgatttcca catccgttac aaacagctcg
     4201 acctgtgggc gcgattccag gactttcaga cccgtatccg tgacgcgatt atcaagcgcc
     4261 agtcgctcga tttcattatg gccggtttca acggtatcac ccgtgcggcg acctccagcc
     4321 gtaaaaacaa tccgatgctg caggatgtgg cggtgggctg gctgcagaag taccgcaatg
     4381 aagctgcagc gcgcgtgatg tcaaaaatca ccgacgaaga cggcaaggtt atttccgatg
     4441 tgatccgcgt gggtaaaaat ggtgactatg aaaacctcga tgcgctggtc atggatgcga
     4501 ccaccaacct gattgatgag atttatcagg atgacccgga gctcgtcgtt atcactggcc
     4561 gtaagctgat ggcggataaa tatttcccgc tggtcaacaa gacgcaggaa aacagcgaaa
     4621 cgctggccgc tgacatcatc atcagccaga agcggatcgg caacctcccc gccgtgcgtg
     4681 tgccgtactt cccggcgaat gccctgatgg tgacgcgtct cgataacctg tcgatttact
     4741 tcatggatga cgcacaccgc cgcgccatca ttgaagagcc gaaaaaagac cgtatcgaaa
     4801 actacgagtc aatgaatatt gactatgtga tcgaggctta cgcggccggt tgcctgattg
     4861 agaacatcaa tttaggtgac ttcaccgcac ctgccgcacc ggaaagcgga gagtaagcca
     4921 tgacgagtcc cgcagcgcgt cacatgatgc gggtctcggc ctctgaaact gcgcggcggg
     4981 ctgctgctcc gctgcgtaat gcaactgcct atgagcagat gctcgtcaag ctggccgcag
     5041 actgtcgcac gttaaaacaa atccgctcca acgagcgcaa ggcagacaaa aagcgcgagc
     5101 tgttgccgtt ttatctgccg tgggtgggtg gcgttctcag ctccggtaaa ggggcgcagg
     5161 atgacattgt catgaccgtc atgctgtggc gtctcgatgc ggatgacatc gccggtgcgc
     5221 tggagattgc ccgctatgcg atgacctatg gcctgaccat gccgaccggc ggccaccggc
     5281 gcaccacgcc gtatttgctg gccgaagagg tcgccctgtc agcgcagcgc ctgctcgatg
     5341 cgaaacagcc tgtcgggctg ccgctcctgc tcgacaccat cgcactgacc gaacgggcag
     5401 acatgccgga tatcgtgcgc gcgaagctgc acaaaattac cggctacgtg ctgcgtgagg
     5461 ctggccgtct gactgacgcg ctgacgcacc tgcagcgtgc gatccagtta gagcgggcta
     5521 tcggtgtgaa aaaggatatt gaacagctcg agcgcgcgct gaaacccaaa gcagaacctg
     5581 cacccaaaca gaataaaccg cgcacgcgca aacctgccgc taaaccggcg gcacggcgcg
     5641 ggcgtccccc gaaagcggca aaagccgcag gttaacagag cgctccccga gccgggcggc
     5701 acgccggtca atgcgggcat tgattgccct gactgcgacc ggcgtccacc gcccacccat
     5761 tacccgaggt tgtcatgacg acagtgatta ttgagccaaa aaaagagccg caggacgtgc
     5821 cgggcgtggt cattccgcca ccgggcgtga gtgaacctgt aataaaaaac accttctttt
     5881 ttcctgatgt ggatccgaag cgtgtgcgtg agctgatgcg tctggagcag accgtttccg
     5941 cgctgcgcct gaatgatgcg attaaagccg gtatggctga aaccaatgcg gagcttgctc
     6001 tgtggcgggt tgagcagatg gccgcagggc atgacacgct ggctgatgtg cctgccgatg
     6061 atatcgatgg cgaaagcgtg cgctgttttc actatttccg cgccgtctgc gccatgacca
     6121 gcgccacgct gtttgagcgt tatcgcggca tcgatgcgac ggcgaaaggc gaccgtaaag
     6181 cggaaagcac tgaggcggtt atcgatgaac tgtggcggga tatgcgctgg tctgtggcgc
     6241 gtattcagga caagccgcgc tgtattgtcg gtcaaatctg atgaaggtcc gggcgatgca
     6301 gggtgacacc ctcgatgcga tttgcgcccg gtattacggg cgcactgagg gcgtcgttga
     6361 aacggtgctg tgggcgaatc cggggctgtc ggagctgggc gttattctgc cgcacggcac
     6421 gacaatagaa ctgcccgaaa ccgacagcgc cccgaaaact gaaacggtga atttatggga
     6481 ctgagtgtgg aaaaaatcac gacgtttttc gcttactggc tggccgtggg gctggcgtat
     6541 ttcggggcta tgtcccccga aaagctggcg ctctatgtgg ggagtgcctg cgccattttt
     6601 accgcgctga cgaattactg gtttaagcgt aaaacctacc gctacctgac ctcacttgga
     6661 cccgataagg gggctgcccg tgagctcaat cattaaacgc tgcagtgtgg ccgccgtgct
     6721 ggcgctggcg gcactggtgc ctgattttcg tctgcttaac acctcgcccg aggggctggc
     6781 actgattgcc gacctcgaag gatgtcgcct gacaccttac cagtgcagcg cgggagtgtg
     6841 gacgtcgggc atcggccaca ctgccggggt ggtcccgaaa ggggatatta ccgaacagcg
     6901 cgcggcggag aatctcattg ccgatgtgct caacgtcgag caacggctcg cggtctgtgt
     6961 gccggtggat atgccaccgc gcgtctataa ctcgctggtc agttttgcgt ttaacgtcgg
     7021 aaccggtgcg gcctgtcggt cgactctggt ctcttatatc aagcgtcacc agtggtggca
     7081 ggcatgcgac cagctcaccc gctgggtgta tgtcaacggc acaaaaaata aagggctgga
     7141 gaaccgccgt gcgcgggagc gggcttactg cgtaaagggg atgcaatgaa agtgctgatg
     7201 attctgctgg cagggttgct cgccatggtg ctgtggctgc gccacgataa cgtgaactta
     7261 tcccggtctt ttgagaaagc gagccgcgtt gccagcgagc aaaagacgac gattggcatg
     7321 ctgaaaaatc agcttgccgt atcgcagcga atcgcaagtg cgaatgagga tgcgcaggtc
     7381 aggctcggtg atgagctggc cgttgccggt gagcaggcgg taaagcggga agaaaccata
     7441 acgaggttga tgaatgaaaa cgagacgtta cgccgctggt acagcgataa gctgcctgat
     7501 gctgtgcgtc ggttgcacat ccgaacgggc tgcgcctccg ccgcccgttg tttacaacgc
     7561 ctgcccgaag gtgagtctct gcccgatgcc gggaagcgac cccgtcaata acggtgatct
     7621 gagtgccgat attcggaggc ttgagcacgc gctcaccgcc tgtgcaatta aggtcgaaac
     7681 catcaaagac tgtcaggata aaatcgatgc agaaaatgaa aagcctgcgc aaagcgctga
     7741 atgacgccgt ccctcagatc ctgaataacc ccgagatgat gcgcatcttt gccgatgagg
     7801 ggaatatcga tgcgcgtctc gcagactcgc tgtctcatga aaagaattac accctgaatg
     7861 tgattgtctg cgattttgtg ggcgaccctg acctgatttt cgtgccggtg gcggtgtggc
     7921 tgcgtgagaa ccagccggat atctgcacgc tggatgaggg gcgcaaaaag ggctatcgat
     7981 tccagatgga tttaaacgac ggtgataatg tggatatcag tatcagcctg caactcaccg
     8041 agcgcaccct cgtcagagat gaaaacggcg cgttacacgt cagctatgcg cctgaaccgc
     8101 cattacctga gcctgtcacg cgaccgactg agctgtatat caatggcgag ctggtgagta
     8161 agtgggatga atgaatttaa gccttttgat gacaaacttg cggggttgat tgcggcaata
     8221 tcaccggcgg gtcggcgtaa gctggccgct gaaatagcaa agcaactgcg cagatcgcaa
     8281 cagcaacgca tcaaacagca aaaagcgcct gatggcacgc cgtatcaggc gcgaaaacgc
     8341 cagccgctca gagcgaagaa agggcgtatt aagcggacga tgtttcagaa gttgcgaacg
     8401 aaccgctaca tgaaagccag aggccgcgat gatgcagcgg tggtcgagtt taccggcaag
     8461 gtgcaacgta ttgctcagat tcatcagctc ggacttaaag accggccaaa cccacatgct
     8521 caggacgtgc aatacccaga acggcagttg cttggtgttg actttggaga caatttgttg
     8581 attgaaaaat tggttattga acatctaaat tgactattta cggttgcaag tctcataaga
     8641 cgaatcctag cttaccgacc ttttgacctt aatcataaaa aatggtaaat attgttgttg
     8701 tctgctacct cgttgatttt ttaagctttt acttacaagg attgaagcat gtctaacgat
     8761 gataaaacat tgaatttatt ccccatagat tatccatttg agactttatg ttctaggatg
     8821 aagtccaatc ccatcaaact aaaactgaat ccagactttc aaagaaagta caaatgggat
     8881 caggacggat ggctgcgatc ttcaaaattc attgaatctt gtttaatgcg tattcctctt
     8941 ccatcttgtt actttgcaga agatgatagc ggcaatcata ttgtaattga tggtgttcag
     9001 cgattaacca caatacagaa attttttgat gacgagttcg ctttggaggg aatgactaca
     9061 tttaaagagc ttgaagggaa aaagttttct gaattaggat ctctacgttc agagttaga
//
LOCUS       DACAOP010000140         8993 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.140, whole genome shotgun sequence.
ACCESSION   DACAOP010000140 DACAOP010000000
VERSION     DACAOP010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8993
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.140"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            13..267
                     /locus_tag="IT892_004072"
     CDS             13..267
                     /locus_tag="IT892_004072"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137215.1"
                     /translation="MEILREKRKAFSTNRYMLVIEDFNGGLSDSVYRIIETTKDFRPE
                     DRFNSSKPTYTTLSHIDFSEDEEVNNKSLITLKNKFFDLI"
     gene            305..649
                     /locus_tag="IT892_004073"
     CDS             305..649
                     /locus_tag="IT892_004073"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137216.1"
                     /translation="MEYTINFFHNLDDILKGTHLRLIFVAIIGFAIFMKGIRHVINDF
                     PVLVSYYKRAKREGYTDFQFFINNAHNIGMYLLVLFATLLSAYAIYFSAERINTIQEL
                     QESTVITTPKNK"
     gene            750..1901
                     /locus_tag="IT892_004074"
     CDS             750..1901
                     /locus_tag="IT892_004074"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019997.1,HMM:NF037521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1738 domain-containing protein"
                     /protein_id="HAP3137217.1"
                     /translation="MAFYKKRTSSDPGMSKEDKMNLFMETRKAEIIESLNQLPDDKPI
                     WQSPVFTTKYINPVSGAKYNIENSVLLLGQMRERALKNPDEKEKLPFFMTFNQAKNSG
                     LIVPKGTKSFAILKRFGKKYEVTKLDEATGQEEVEERFRRAASIDFVFNISDLEGELS
                     AKLQRNMSMGFSKATNEEAKVILEALEATSPVKITRVTDFNSSSGSYYVPSAEFINLP
                     PSSLFRNVIEEISTLAHEIAHSWGHSSRLNRETLNTYSQDNKARAEEELVANVASQAV
                     VNHFGLELDDKRQFESYEKNHDTYDFGWAKLLKDNPDSITTAIQNADKTAGKMIAEVE
                     LWLSNKLKDNPDLAVSEFIKDRINKKQEKEETPEENPTPEISTRRKPSI"
     gene            2000..2599
                     /locus_tag="IT892_004075"
     CDS             2000..2599
                     /locus_tag="IT892_004075"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137218.1"
                     /translation="MSFDPEISTKEKFQDLMDICKSNFQMTDDEAKCFYIMMNRCTPR
                     VDMGPNRVGKGFNELPKSMFDLSRRFEEWENLVTLGHASNYKGIPFEIYIKNNNTLAE
                     ILLEPAEAMLLNQMCNFNNIPKPPSKLTMAKIFKFYKDSEMPTVKVNHSSTSFKEHKF
                     HPIYESCEQIIAEHEQQKISQVFQNGTPGSGASKPKRRM"
     gene            complement(2628..3176)
                     /locus_tag="IT892_004076"
     CDS             complement(2628..3176)
                     /locus_tag="IT892_004076"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137219.1"
                     /translation="MALRIRDKKERVNLFLEYFDCTYEVKPRTPFNQPDVLTMNFYYA
                     LKLFCKNYNEIYDAPHHWKDKIPALFTGYKMLFESEELKVSFICGTMAKKARIREKYH
                     VSHAVTFRVPYHWNGSREPVGIATYHLAIDKTLNDEQIEQEFYKLLTLFEYSLKYHQG
                     KVPVFKIDLHNPEVIRPTYEKE"
     gene            3376..3729
                     /locus_tag="IT892_004077"
     CDS             3376..3729
                     /locus_tag="IT892_004077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP3137220.1"
                     /translation="MNLLHFIETKVFQRVIDGLLSPDELREFQEVLRQDPTAGDTISG
                     TGGCRKIRWALPGMGKSGGIRVIYYYLTADNEVFLLIAYPKNEKDNLTNAEKNQLKKA
                     VEGIEQASQEARGKK"
     gene            3726..4016
                     /locus_tag="IT892_004078"
     CDS             3726..4016
                     /locus_tag="IT892_004078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system MqsA family
                     antitoxin"
                     /protein_id="HAP3137221.1"
                     /translation="MRKELFDDLIESVNEAVAIKRGLVAPARVTTFEMPDVKAIRTKA
                     KLKQNEFAQVVGVSPSLVQAWEQQKRTPTGSSLKLLRVIEKHPDMLNLFRTA"
     gene            4068..4442
                     /locus_tag="IT892_004079"
     CDS             4068..4442
                     /locus_tag="IT892_004079"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137222.1"
                     /translation="MIKRYSERLAELELLQNRLLLSFRTDDDDYILTVCRQISDTGLN
                     LKYSNTDYIFHYINCCSYHREPSFIVIGLLLSLQAKKTVMAYRLFKKLYIDKKDSHSL
                     TDNIQRTAGSLLSVMNRKESAA"
     gene            4439..5149
                     /locus_tag="IT892_004080"
     CDS             4439..5149
                     /locus_tag="IT892_004080"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137223.1"
                     /translation="MKNLIRKIEKYFNQELDFSNISSTTIDGNENLLSGAITFLMHKN
                     IDSEVSLSLLQNILDSGVNVNHKIEESNSPLIKVFLYQWKNSDFKAKVIEILLSCGAD
                     QNIPGHNLLEYATAKECKLLLAYGADLERIADNRLQTAIFDCYCLDKLSVLIDSGANI
                     NHSNKKGKTCLACYYKKSEYVRFLLDNGINTESFLNDSDYTEEQKKTVNAMIAQRDNE
                     QLKTVFGNKLESKGMIRI"
     gene            5465..5644
                     /locus_tag="IT892_004081"
     CDS             5465..5644
                     /locus_tag="IT892_004081"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137224.1"
                     /translation="MNNRINKVPYSSSGDKPALPKTDKVKFYHEDEYAFAHFMYDDTA
                     TEQDNAETKSENNND"
     gene            5663..6451
                     /locus_tag="IT892_004082"
     CDS             5663..6451
                     /locus_tag="IT892_004082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HAP3137225.1"
                     /translation="MEKQFKKTLASIQTRSNRSHSDTVREFFNCVSYTMIMNSLFQLE
                     QRELFYSGSNIYGFNQLAIQSGFIEKSIMLTDRHKFCIEEKFYNQFDNEIIDTANLIS
                     LEIQKQPLTDVFNNIFQELYLTGKKGENLGQFLTPNRLSEAICRFVGWEKNIKYNIGD
                     ICAGTGSLLFPLLREIYSKEGFEGVQKIKLIYNDIDSLMAQLFMAQILTNMAYHNLDF
                     KSLHVYIGNAITEYDTVSTLFLRFKQNKLVAQRVLEIDKEKKAA"
     gene            6472..7260
                     /locus_tag="IT892_004083"
     CDS             6472..7260
                     /locus_tag="IT892_004083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HAP3137226.1"
                     /translation="MKKQFYKTMGNISTRSNRSHSDTVREFFNCVSYTMIMNSLYQLE
                     KREQFYSGETTYRFSTILNELNVSERNIIITNRHKFKVDSVFYKRFANEITYISGVLS
                     NEIGKNPLTDIFNELLEDLFLTGKKGDNFGQFLTPTDISELLTDIVYTTSKDKYKIAD
                     SCAGTGSLIFPLIKRIFFKEGFEGIQKVELFYNDKDSFVSQLFIAQILTNMIYHNLDF
                     KDLRIYIGDAITEYDTINTLFLRVKQNKVVAQRVLEIDREKKAA"
     gene            complement(7437..7883)
                     /locus_tag="IT892_004084"
     CDS             complement(7437..7883)
                     /locus_tag="IT892_004084"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137227.1"
                     /translation="MERISIGKLRYIEPVIYQSKEDARKASLSGKFIVYALGLTEQAY
                     RRLESFCIKNNLVEVYKMDILDDPHDIFNELRTKEFMLRERSTNGREGEFRVYSCNVY
                     DSQILGNDRSKRYRSGNPKCPTPTIEQLYFKLIKENGSVIKMAYSI"
BASE COUNT         3139 a         1550 c         1639 g         2665 t
ORIGIN      
        1 acggggtgac ttatggaaat attaagagaa aaaagaaaag cattttcaac taacagatat
       61 atgttagtga ttgaagattt taacggtggc ttatcagatt cagtatacag aataattgaa
      121 acaacaaaag attttagacc agaagacaga tttaactctt caaaaccaac ttacacgact
      181 ttaagccata ttgatttttc cgaagacgaa gaagttaata ataaaagtct tattacatta
      241 aaaaacaaat tctttgacct aatataatta taacaggggg tgaaagcccc cacaggagaa
      301 caatatggag tatacaataa atttctttca taaccttgac gatatattaa aaggtactca
      361 tttaaggctt atcttcgtgg ctatcattgg atttgctatt tttatgaaag gtatcaggca
      421 tgttatcaat gattttccag tgttggtaag ctattacaaa cgagcaaaac gagaaggata
      481 tacagatttc cagttcttta ttaataatgc tcacaacata ggaatgtatc ttttagtttt
      541 gtttgccact cttttaagtg cctatgctat ttatttcagt gcagaaagaa taaacacaat
      601 tcaggaattg caggaaagca ctgttattac cacacctaaa aataaataat taaatttgaa
      661 tattaaaaaa tctccgggta ttgttatttt acccggttgt tttattatat atatagccat
      721 taataattat tataaaaaag gaggtattta tggcatttta caagaaaaga acttccagtg
      781 atcccggaat gagtaaagaa gataaaatga acttattcat ggaaacacga aaagcagaaa
      841 ttatagaatc tcttaaccaa ttacccgacg ataaacctat atggcaatcc cccgttttta
      901 caaccaaata cataaaccct gtgagtggtg ctaaatataa tatcgaaaac tccgttttac
      961 tcttaggtca aatgagagaa cgagctttaa agaatccaga cgaaaaagaa aaactcccct
     1021 tcttcatgac ttttaaccag gctaaaaatt cgggtctaat cgttccgaaa ggaacaaagt
     1081 cttttgcgat attaaaaaga ttcgggaaga agtacgaagt aaccaagctg gacgaagcga
     1141 caggacagga agaggtagaa gaaaggttca ggagagcagc ttcaatagat ttcgtattca
     1201 acatttcaga tctggaagga gagctatcag cgaagctaca acgaaacatg agtatggggt
     1261 ttagtaaagc caccaatgaa gaggcaaaag tcattctgga agcactggaa gcgacctcac
     1321 cggtgaagat caccagggta accgacttta acagttcgtc aggctcttac tatgtgccgt
     1381 cagcggagtt tatcaacctt cccccttctt ctctgttcag gaatgtcata gaagagatct
     1441 ccacccttgc acacgagata gcccactcct gggggcatag cagccgttta aacagggaaa
     1501 ccctgaatac atacagccag gacaacaaag cacgagctga agaagaactg gtagcgaatg
     1561 tggcaagcca ggcagtcgtt aatcattttg gtctggaact ggacgacaag agacagtttg
     1621 agtcatacga aaagaaccat gacacttatg attttggctg ggcgaagctt cttaaagaca
     1681 acccggacag cataacaacg gctatccaga atgcagataa aacagcgggt aaaatgattg
     1741 ccgaagttga attatggtta tcgaataaat tgaaagataa tccagatctt gcggtatcag
     1801 aatttattaa agacagaata aataaaaaac aggaaaagga agaaacacca gaagaaaacc
     1861 ctactcctga aatctctacc aggagaaaac cttctatctg attaagtatt ccactggtca
     1921 cattttaaat caatattgca ttgtatcttt attatttaga ggtacaatgt atttataaca
     1981 acaaaacgga gaatataata tgagtttcga tccagaaata agcacaaaag aaaaatttca
     2041 agatttaatg gatatatgca aatccaattt tcaaatgact gatgacgaag caaagtgctt
     2101 ttacattatg atgaatagat gcacccccag ggttgatatg gggccaaaca gagttggaaa
     2161 gggatttaat gaattaccta aatcgatgtt tgatttatca agaaggtttg aagaatggga
     2221 aaatttagtt acattgggtc atgcttcgaa ttataaaggt attccttttg aaatatatat
     2281 aaaaaacaat aataccttag ctgagatcct ccttgaacca gccgaagcaa tgctacttaa
     2341 tcaaatgtgt aattttaata acatacctaa accaccgtca aagctaacaa tggcaaaaat
     2401 atttaaattt tataaagatt ctgaaatgcc aacggttaaa gtcaatcatt caagcacttc
     2461 atttaaagaa cataaatttc atcctatata cgaatcatgc gaacaaataa tagcagaaca
     2521 tgaacagcaa aagatatcac aggttttcca gaacggcaca cccggcagcg gggcaagtaa
     2581 acccaaaaga agaatgtaat ataaaaggag gttttaccct cctttgttta ttctttttcg
     2641 tatgttggtc ttatcacttc tggattgtgt aagtctattt taaagacggg tactttccct
     2701 tgatgatact ttaatgagta ttcaaaaaga gtgagtagtt tgtaaaattc ttgttctatt
     2761 tgttcgtcgt ttaaagtttt atcaatcgcc aggtgatagg tggcaatgcc tacgggttct
     2821 cttgaaccat tccagtgata aggaacacgg aaagtaacag catgagatac atgatacttt
     2881 tcccttattc ttgccttttt tgccattgtt ccacaaataa aagacacttt taactcttca
     2941 ctttcaaaaa gcattttata tccagtgaat aaagctggta ttttatcttt ccagtgatga
     3001 ggggcatcat agatttcatt gtaattttta caaaaaagct ttaaggcata gtaaaaattc
     3061 attgtaagca catcaggctg attaaatggg gttcgtggtt ttacttcata agtgcaatca
     3121 aagtattcga ggaataaatt tactctttct tttttgtctc ggattcttaa tgccatattt
     3181 atctcctttt taattgttat cactcattca ttatcaggaa ataaattaat atcaatatgt
     3241 accagttatg tttctggata tacggcttac ccacttaaaa gaacggttaa cttatcatca
     3301 aaaagggctt gcaactctta cacagtacca ctaagataga ctcatacagt gtgcgagtga
     3361 gatagagtta agggaatgaa tttactacac ttcattgaaa ccaaagtctt tcagagagta
     3421 atcgatggat tgctttcacc cgacgaactc cgggagtttc aggaagtgtt aaggcaagat
     3481 cctaccgctg gcgataccat atcaggtaca ggcggttgcc gtaagattcg ctgggctttg
     3541 cctggtatgg gtaagagtgg tggtatcagg gtcatatact actatctgac agcagataac
     3601 gaagtattcc ttcttatcgc ttatcctaag aacgagaaag acaatctcac caatgctgaa
     3661 aagaaccagt tgaagaaagc cgtagaaggt atagagcaag cctcccagga ggcaaggggg
     3721 aagaaatgag aaaagaactc tttgacgacc tgatcgagag tgtcaacgaa gccgtagcca
     3781 tcaaacgggg tcttgttgcc ccagctcgtg ttacgacctt tgagatgccc gatgtgaaag
     3841 ctatccgcac gaaagcgaag ctcaaacaaa atgagtttgc ccaggtagtg ggtgtctccc
     3901 cttctctggt gcaagcctgg gaacagcaaa agagaactcc caccggtagc agtcttaaac
     3961 ttttgcgggt cattgaaaag catccagata tgcttaacct gttcagaaca gcataagccc
     4021 cttagctggg gcttttttgt ttaatctgta ttaaccaggg aacagcaatg ataaagagat
     4081 acagtgaaag acttgcagaa ctggaactat tacaaaacag actgttgctg tcgttccgaa
     4141 cggacgacga cgattatatt ttaactgtat gccgtcaaat cagcgataca gggctaaatc
     4201 tcaaatacag taatacagat tatattttcc attacataaa ctgttgctct taccacagag
     4261 aaccaagttt tattgttatc ggcttactgt tgtcattaca ggctaaaaaa accgtcatgg
     4321 catacagact atttaagaag ctgtatatag ataaaaaaga tagccacagc ttaactgaca
     4381 acattcaaag aacggctggt agtttactgt ctgttatgaa cagaaaggaa agtgcagctt
     4441 gaaaaattta atccgtaaaa tcgaaaaata ttttaatcag gaactggatt tcagtaatat
     4501 ttcatcgaca acaatcgacg gaaatgaaaa tcttttatct ggtgctatta ctttcttaat
     4561 gcacaaaaat attgatagtg aagtgtcatt atctctactt caaaatattc tcgatagtgg
     4621 tgttaatgta aatcataaaa tcgaagaatc taacagcccg ttaataaaag ttttcctgta
     4681 tcaatggaag aatagcgact ttaaagcaaa ggttatcgaa atacttttat catgtggagc
     4741 agaccagaac atacccggtc acaaccttct tgaatatgcc acagcgaagg aatgtaagct
     4801 cttactggct tatggtgcag atctggaaag aatcgctgat aatcgcttac agacggctat
     4861 ctttgattgc tattgtctcg ataagctgtc tgtactgata gattcagggg caaacattaa
     4921 tcactcaaac aaaaagggta aaacctgcct ggcttgctat tacaagaaaa gcgaatatgt
     4981 cagattttta ctggataatg gcattaatac agaaagcttt ttaaatgata gtgattacac
     5041 ggaagaacaa aagaaaacgg ttaatgcaat gattgctcaa agagataacg agcaattaaa
     5101 aactgtattc gggaataaac ttgaatccaa aggaatgatt agaatatgaa aaaagccact
     5161 aatggggtta agtggctttt aagggtactt actaacaaat ttcagagtta catggaaaat
     5221 ccttatcctg tatttatatt tctatcaggt ttttataaac tgtcaacact tccacgaata
     5281 aaaacataat taatataaca aatagcactt tttgtatttt tataattgtt taataatatc
     5341 atcaccttac aatcataaat aaaatagaaa acgcttgctt ttattttgca ggcaaatata
     5401 tatctatact tattttataa tttaatatat attatgttta ttccaataat aaaggagaat
     5461 ataaatgaat aaccgcatta ataaagtacc ttacagtagt agcggtgata aaccagcact
     5521 ccctaaaacc gataaggtta agttttatca tgaagacgag tatgcttttg ctcatttcat
     5581 gtatgacgat acagcaaccg aacaagacaa tgcagagact aaaagcgaga ataacaacga
     5641 ctaatataaa taaggggtta ctatggaaaa acaattcaaa aagacactgg caagcattca
     5701 aacacgatct aatcgctcac attctgatac agtcagagag ttctttaatt gtgtgtctta
     5761 caccatgatc atgaatagcc tttttcaact tgaacaaaga gagctattct attcaggaag
     5821 taatatatac ggtttcaatc agcttgcgat acaatccggg ttcattgaaa aatccataat
     5881 gttaaccgat agacataaat tttgtatcga agaaaaattt tataatcagt ttgataatga
     5941 aattatagac acagctaact taatctcact tgaaatacaa aaacaacctt taacagatgt
     6001 tttcaataac atatttcaag agttgtattt aacaggtaaa aaaggtgaga atttggggca
     6061 gttcttaaca cctaacagac tttcagaagc aatatgtaga tttgtaggct gggaaaaaaa
     6121 tattaaatat aatattggtg atatttgtgc tggcacaggc tctttactat ttccgttgct
     6181 tagagaaatt tacagtaaag aagggttcga aggtgtccag aaaataaagc ttatttataa
     6241 tgatattgat tcgctcatgg ctcaattatt tatggctcaa attcttacta atatggcata
     6301 tcataattta gattttaaat ctctccatgt gtacataggt aatgcaatta ctgaatatga
     6361 tactgtaagc actctttttt tgagatttaa gcaaaataaa ttagtagctc aacgggtatt
     6421 agaaattgat aaagaaaaga aagcagcgta attctaagaa ggataaacaa aatgaaaaaa
     6481 caattttata aaacaatggg aaatatttca acacgatcta atcgctctca ttcggataca
     6541 gtcagggagt tttttaattg tgtgtcttac actatgataa tgaatagtct ttatcagtta
     6601 gaaaaaagag aacagtttta ttcaggtgaa acaacatatc ggttttcaac cattctcaat
     6661 gaattgaatg tatcagagag aaatataatc ataacaaata gacataaatt caaagttgat
     6721 agtgtgtttt ataaaagatt cgcaaatgaa ataacatata tttcaggagt attatctaat
     6781 gaaattggaa aaaacccact aactgatata ttcaatgagt tgcttgaaga tttattttta
     6841 acaggtaaaa aaggtgacaa ctttggtcaa tttcttacac ctactgacat atctgaactt
     6901 ttgacagata tagtttatac taccagtaaa gataaatata aaatcgctga tagctgtgct
     6961 ggtactggtt ctttaatatt cccattaatt aaaaggatat tttttaaaga agggtttgaa
     7021 ggtattcaaa aagtagagtt gttttataat gacaaagatt catttgtatc tcagttgttc
     7081 atagctcaaa tattaactaa tatgatttat cataatttag attttaaaga tcttcgtatt
     7141 tatattggtg atgctataac tgaatacgac actataaaca ctttattttt aagagttaaa
     7201 caaaataaag tagtagctca aagagtatta gaaattgata gagaaaagaa agcagcataa
     7261 taaaaataat tacgacaaag ttggcgcttt gtcgtggtgt aagcagttag gtggtaacat
     7321 gtgaatgtta cttaatatca ataaaaggaa ggaaataaaa atgagtgtaa catttttaat
     7381 ctatatacag atttatcaga tataaattac ttgtcaatca tcatcaattg aataatttat
     7441 attgaataag ccatttttat cacggaaccg ttttctttta taagtttaaa gtaaagctgt
     7501 tcaattgttg gagtaggaca tttaggatta ccagaacgat accgcttgct acggtcgtta
     7561 cccaggatct gactatcata gacattgcac gagtaaactc taaactcccc ttccctgccg
     7621 ttcgtgcttc tctctcttaa catgaactct tttgttcgta gctcattaaa aatatcatgt
     7681 gggtcgtcca ggatatccat tttatagact tcaaccagat tgtttttaat gcagaacgat
     7741 tccagacggc gataagcttg ctcggtcaga ccaagagcat agacaataaa tttccccgac
     7801 agggaagctt tacgggcatc ttcttttgac tggtaaatta ctggttctat atatcgtagt
     7861 ttgccaatac tgatccgttc caccgacagc cccgttctat taatgatttc atgtagctct
     7921 tttattccaa tcctacccta tccgctctca aatatccgct atggctaatg aatttttttg
     7981 gtagtggtag ggtgtttgta tgggttaggt gcaaaagtcg ctcagaaggg cttacaggca
     8041 ggatttgagc tattggggtg tttttggtta atcggtgagc agatttgaag ggttggccac
     8101 tcttgcagat cgataatgct cgattaaggg aacagggctt gccgttcctg gcgaactgga
     8161 ttgagtcgta acctgattag gctacagtgt agtatattat attatagtat agtgtattac
     8221 cttttcgatc atacggctgg cattgctaaa cttttatcaa tcgacggtac cgactctacc
     8281 cattccacga aggggaatta accgtggaac actacttacc agtaatggcg gggcatacag
     8341 ccccaaaact ttcaatgttc cccgttccac caaaataagg caacatacca tagggaagag
     8401 tgtagtatag tatattgtag tatattgcca tttcattttc tcaaaccgac ttaccacata
     8461 tcgatgacag ggaatgtcat tgctaccgcc agtgcttcaa acttttatca agtggctgta
     8521 ctgttttact cttttcctga tcacccgttc cgggcaggta cccaaccaaa tagaatgtag
     8581 aaaaatagaa attccccgtt caggttttct ataatctcaa accatcaatt tacaatgtag
     8641 tatagtatag tgtattacca tgttcagatc taaaaacacc cgttccgggc aataatagaa
     8701 aatagatttt gagatttacc gttatttccg atcatcccga ttctatttag tgtacaatac
     8761 tcacaacaac agcgaaatcc cccaggtgtt ccaccctgaa aagccattat tccacaacca
     8821 aaaagggtgg tggaatgcaa gtggaacaaa taaatcctta tatatcaatg ctctacggca
     8881 tattccacag attccaccca ttccaccgat acactcaatt ctcatagaga gatattaaat
     8941 agaatacgga aatagattga gaaatagatc tataagccta tttatctctc aat
//
LOCUS       DACAOP010000141         8895 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.141, whole genome shotgun sequence.
ACCESSION   DACAOP010000141 DACAOP010000000
VERSION     DACAOP010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8895
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.141"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            466..1368
                     /locus_tag="IT892_004085"
     CDS             466..1368
                     /locus_tag="IT892_004085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1281 domain-containing protein"
                     /protein_id="HAP3137228.1"
                     /translation="MHFSGEPAQIAEIKRLASGAVTPLYRRATNEGIQLFLAGSAGLL
                     QTTEDVQFEPCPGLTDAGRGVVSPENIAFTRWLTHLQNGVLLDEQNCLMLHELWLQSG
                     TGQRRWEGLPDEVRETITVHFTAKRGDWCGFWSNEDVSVWWNRLCDNVLPEKTMPFDL
                     LTVLPTRLDVEVNGFNGGVLNGVPSAYHWYTEQYGVKWPVGYEVNISRQGENFIQVDF
                     DTPWCQPESNVVAELSRRFGCTLEHWYAEQGCNFCGWQRYERGELVDVLWGELEWSSP
                     TDDDELPEVTAPEWIVDKVAHYGG"
     gene            1372..1676
                     /locus_tag="IT892_004086"
                     /pseudo
     CDS             1372..1676
                     /locus_tag="IT892_004086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052644.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1753..2436
                     /locus_tag="IT892_004087"
     CDS             1753..2436
                     /locus_tag="IT892_004087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HAP3137229.1"
                     /translation="MSRFVLGNCIDVMTRIPDNAIDFILTDPPYLVGFRDRSGRTIAG
                     DKTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRFMAAWKNAGFSVVGHLVFTKNYT
                     SKAAYVGYRHECAYILAKGRPRLPQNPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAAN
                     DDWFMPEAA"
     gene            2437..2658
                     /locus_tag="IT892_004088"
     CDS             2437..2658
                     /locus_tag="IT892_004088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137230.1"
                     /translation="MNYAGHEKLRADVAEVANTMCDLRARLNDMEHRCRFDSDVLVER
                     LTRQTLYRANRLFMEAYTEILELDSCFKD"
     gene            2672..3106
                     /locus_tag="IT892_004089"
     CDS             2672..3106
                     /locus_tag="IT892_004089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 domain-containing protein"
                     /protein_id="HAP3137231.1"
                     /translation="MYGTCETLCRELAAKYPGDAPLMLVIWSPEEIQALADGMEISLT
                     DHEIRTVLARMEDIPEDQRTESGISSAAVMEIISNVSENRQVTVPAELLASLIQTAEQ
                     ALWKREWAARDNGLAVPECVTRRQAVVNQARTLLKNNTHENN"
     gene            3157..3921
                     /locus_tag="IT892_004090"
                     /pseudo
     CDS             3157..3921
                     /locus_tag="IT892_004090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001476318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3806..4377
                     /locus_tag="IT892_004091"
                     /pseudo
     CDS             3806..4377
                     /locus_tag="IT892_004091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052648.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1472 domain-containing protein"
     gene            4473..4775
                     /locus_tag="IT892_004092"
     CDS             4473..4775
                     /locus_tag="IT892_004092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HAP3137232.1"
                     /translation="MMPEYQGGFWHFIRLPDGGGYMMPDGDRFHMVNGANWFDRTVSA
                     DAAGIILTSLVINRQLWLYHDSGDAGLTQLYRMRDAQLWRHIEFHPECNAIYAALD"
     gene            4822..5244
                     /locus_tag="IT892_004093"
     CDS             4822..5244
                     /locus_tag="IT892_004093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 domain-containing protein"
                     /protein_id="HAP3137233.1"
                     /translation="MYCTVKEIIREVLDTDVPDSECVFAVVLTRGDVRHIAQDWSLTD
                     DELETVMQRLDDAFEYGADVSVVHGVVRELMEEKRASRQVTVPAVMLEKVMALAGSEM
                     KRLYAVGSENGGDGDAFVREEREAMDVVLQALDGETMS"
     gene            5241..5432
                     /locus_tag="IT892_004094"
     CDS             5241..5432
                     /locus_tag="IT892_004094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137234.1"
                     /translation="MNISTETREILRNYRAVINARRREMGQKPLTTAQIVDEICDFVA
                     NQQAVFLGGHYILQGSRNR"
     gene            6467..6697
                     /locus_tag="IT892_004095"
     CDS             6467..6697
                     /locus_tag="IT892_004095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137235.1"
                     /translation="MTVSIVSPSAAAVKPRRHPRFRREDIPAPEIDPVLKAFGRHIAR
                     SFHRGRGVHIPAMKNTAFGQVLRTLELKRAFN"
     gene            6749..8110
                     /locus_tag="IT892_004096"
     CDS             6749..8110
                     /locus_tag="IT892_004096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3560 domain-containing protein"
                     /protein_id="HAP3137236.1"
                     /translation="MTLAAITMTAPEAASPVQMYRATYSPDDNKLRLYAVSRLDPETY
                     KKVHDAGFRWAPKQALFVAPAWTPGREDVLLSLAGEIEDEDSTLAERQEARAERFTGY
                     SGKRASESAQALDEVERLAAMIPPGQPILVGHHSERRARRDAQRIENGMKRAVMLFER
                     AEYWEERARSALLHAKYKERPDVRWRRIKKIEADLRKAEKTIAQSQKYLTMWRAESLD
                     LNMAKLISSHDHISACFPLDTYPRPAEKSQYEGSRSLWSALDDDIITTEQAREIAIRC
                     HERQIQHQQRWVNHYQNRLIYERAMLDESGGVVTRTQDFEPGGQVFSRGEWLTIIRVN
                     KSNGAVSSVTTPNYSFLGYSGTMKVTPDRITDYKAPSAEEAAVASQAAKRPPVVNYPG
                     EGFREMTKAQWAALPRDCKAVRSVAEAEDHGAYRYRRTMDNNFRLVNVYISDMKITEI
                     PQK"
     gene            8158..8721
                     /locus_tag="IT892_004097"
     CDS             8158..8721
                     /locus_tag="IT892_004097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP3137237.1"
                     /translation="MHSQLRERIRLMRARLDNAAPVAEIRAESQLFVTPAPVCDRLVM
                     LAEISNRDHILEPSAGTGAILRAIRDTAPGAMCDAVEINSGLVRYLRENFNGVRVQCG
                     DFMEWLPVQYYSRVIMNPPFSHGQDIRHILRAFSLLRPGGVLVAVCLNGPRQQEKLLP
                     FSDVREELPRGTFAYTDVPTMIIRLRA"
     gene            complement(8806..>8895)
                     /locus_tag="IT892_004098"
     CDS             complement(8806..>8895)
                     /locus_tag="IT892_004098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus protein"
                     /protein_id="HAP3137238.1"
                     /translation="NNNISNRQMTGMKKQKPPSERPRNERGGA"
BASE COUNT         1881 a         2456 c         2688 g         1870 t
ORIGIN      
        1 tcccactcgt gttgtcggtc tgattatcgg tctgggacca cggtcccact tgtattgtcg
       61 atcagactat cagcgtgaga ctacgattcc atcaatgcct gtcaagggca agtattgaca
      121 tgtcgtcgta acctgtagaa cggagtaacc tcggtgtgcg gttgtatgcc tgctgtggat
      181 tgctgctgtg tcctgcttat ccacaacatt ttgcgcacgg ttatgtggac aaaatacctg
      241 gttacccagg ccgtgccggc acgttaaccg ggctgcatcc gatgcaagtg tgtcgctgtc
      301 gccggcctcc tcacccggtc acgtttcgtc gttcctcctc cacgcgctgc ggcttcgggg
      361 ccgcacctgc attcgtatgc ggtcgcccgg ttacaggtgc ggcacggcct gatggaggcc
      421 gcatgtgaga ggagaattcc catgccaaac tggtgctcga atcgtatgca tttttctggt
      481 gaaccggcac agattgctga gattaaacga ctggccagcg gtgccgtcac accgctttat
      541 cgccgcgcca caaatgaagg tattcagctg tttctggccg gaagtgccgg acttctgcag
      601 accactgaag atgtgcagtt tgaaccgtgc cccggactga cggatgccgg acgtggtgtt
      661 gtatcgccgg agaatatcgc gttcacccgc tggctgacac acctgcagaa cggtgtactg
      721 ctggatgagc aaaactgcct gatgctgcat gaactctggc tgcagagtgg tactggccag
      781 cgtcgctggg aaggattacc ggatgaggtc agggaaacca tcaccgtgca tttcaccgca
      841 aaaagaggtg actggtgtgg cttctggagt aacgaggatg tatcggtgtg gtggaaccgt
      901 ctgtgtgaca atgtactgcc ggaaaaaacc atgccgtttg acctgctgac ggttctgccc
      961 acccgcctgg atgttgaagt gaatggcttt aacggtggtg ttctgaacgg tgttccttct
     1021 gcgtatcact ggtatacgga acagtatggc gtgaagtggc ctgtggggta tgaggtgaat
     1081 atcagccgtc agggagaaaa cttcattcaa gtggatttcg acacgccgtg gtgtcagccg
     1141 gaaagcaacg ttgttgcaga attaagccgc cgtttcggct gcacgctgga gcactggtac
     1201 gccgaacagg gctgcaattt ctgtggctgg cagcgatatg agcgtggaga gcttgttgat
     1261 gtgctgtggg gggaactgga atggtcttcc ccgacagatg atgatgagct gccggaagtc
     1321 accgcgccgg agtggatagt cgacaaggtg gcgcattacg ggggatgaag tatgacggag
     1381 acgggcgggc aaccgcccgt ttcttttccg acaaaggatg tcgccgtgct cctcttttta
     1441 ctgcgccggc tgacgcggcg cggcaggaac gctgcctgtg gtcagtgtcc cgcgtccggc
     1501 gggcacggga cgggcgcttt tactgctccc ggctggcacc ggtgacagtg tacgccagcc
     1561 tgtcgccctt ttctgatgaa cgcccttcaa gccgctttcg cggcatattc tcgccgtcaa
     1621 aaagacgacg gctgcgatat tccacggtcg gcctgacccg ttaccggacg cggtgaacag
     1681 cccacaggca gcggggaacg ggcaccacag gggggccctc ccggtgccct ctgtaagaga
     1741 aggagcgttg ttatgtcccg ttttgtcctt ggtaactgca tcgatgttat gacgcgtatc
     1801 cctgataacg ccattgattt catattaact gacccgccat atctcgtcgg ttttcgtgac
     1861 cgttccgggc gcaccatcgc cggcgataaa accgatgaat ggctgcaacc ggcctgtaat
     1921 gaaatgtacc gcgtactcaa aaaagacgcg ctgatggtga gcttctacgg ctggaaccgc
     1981 gtcgatcgct ttatggccgc ctggaaaaat gcgggattca gcgttgttgg tcacctggtc
     2041 ttcaccaaaa actacacatc gaaggccgca tatgtgggct atcgccacga atgcgcctac
     2101 atcctggcaa aaggccgtcc acgtctgcca caaaacccgc tgccggacgt gctgggctgg
     2161 aaatattctg gcaatcgtca tcacccgacg gaaaagcccg ttaccagcct gcaaccgctg
     2221 attgagagct tcacacaccc gaacgcaatt gtgctggacc cgtttgcagg cagcggctca
     2281 acctgcgtcg ccgccctcca gtccggacgc cggtatatcg gtatcgagct gcttgagcag
     2341 tatcaccgtg ccgggcagca acgccttgcc gccgtgcaac gggccatgca gcagggggcc
     2401 gcgaatgatg actggtttat gccggaggct gcgtaaatga actatgccgg acacgaaaaa
     2461 cttcgcgccg acgtggcgga ggtggccaac accatgtgtg accttcgggc caggctgaac
     2521 gatatggagc atcgctgtcg ctttgattcc gatgtgcttg ttgaacgcct gacacgccag
     2581 acgctgtatc gcgccaatcg cctgtttatg gaggcgtata ccgaaattct ggaactggat
     2641 tcctgcttca aagattgaga aggagacgag aatgtacgga acatgcgaaa cgctatgccg
     2701 ggagctggca gcaaagtatc cgggagacgc gccgctgatg ctggttatct ggtccccgga
     2761 agagattcag gcactggctg acggtatgga aatttctctg accgatcatg aaatcaggac
     2821 cgtcctggcg cgcatggagg acatcccgga agaccagcgg actgaatccg gtatttcttc
     2881 cgccgcggtg atggagatta tcagcaacgt gagcgaaaac cgccaggtga ccgtccctgc
     2941 tgaactgctg gcgtccctga ttcagaccgc tgaacaggca ctgtggaaac gtgagtgggc
     3001 cgcccgtgat aacggcctcg ccgtcccgga atgcgttacc cgccgtcagg cggtggttaa
     3061 tcaggcccgc accctgctga aaaacaacac acacgaaaac aactgatgtt atcgccgcct
     3121 gccctgcggg cggcgataca gggagaacgc ttaatcatga acgaaaacag cacgctgaac
     3181 gcactgattt gtcgtcacgc ccgtaacctg ctgctggcgc agggctggcc ggaagagacg
     3241 gatgttgacc agcgaaatcc gaactatccg ggctggatca gcatttacgt gcggctggat
     3301 gcgccccggc tggcgacgtt acttatcaac cgtcacggcg gcgtactgcc gccgctcctg
     3361 gcctccgcca ttcagagact gaccggaacc ggggcggaac tggtactgtc cggcagtcag
     3421 tggcagtcgc tgccggtact tccggcagac ggaacgcagg tgtctttccc gtatgccgga
     3481 gaatggctga ccgaagacga aatcagggct gttcttgatg cggtgcacga tgcggtacga
     3541 agcatctgtt accaggtggc agaagatgcg cggcgtatcc gtgcggcgct gaccaccacc
     3601 ggtcagacgt tgctgacccg ccagacgcgc cgctttcgcc tggtcgtgaa ggaaagcgat
     3661 cacccctgct ggctcgatga agatgacgaa aacctgcccg tggtgctcga tgccatcgtg
     3721 aaccggggag cacgtttttc gtcggtggaa atgtatctgg tcagtgagtg tattgagcat
     3781 atcctgtcca gtgggctggc ctgcgatgtg ctgcgtatac cggatgaacc gccccgccgc
     3841 tggtttgacc gtggtgttct gcgggaggtg gtccgggaag cccggaccga aatccgcagc
     3901 atggcggatg ccctggcaaa aatccggaaa tgatgacact ggcggggtaa atccccgcct
     3961 ttttcctgcc ggtccccgga cagagcacaa aggaagtcgc cgccggctcc gctttacccg
     4021 gccatgcagg gcatggcctt gtggtttttc agttatgtgg cctcagcgtc gtgtgcgggc
     4081 tgtgccgtgc ctccatctta gccgggctgg cgttgatgca agggtacgct tcgccgctgc
     4141 ggtcacccgg tccctccttc ccgtctgccg tgattttccg gtcgttcacc cgctcagatt
     4201 tcgcggtctc accctgcaac tcccgtcagc cgtgtgcgtc aggctgcggc ttcccttgcg
     4261 cccctgcatc cccgcctgtt cgcccggctt ttatggaggc acggcaccgc ccggtgtcgc
     4321 ggaatatgtg aacaacggag gaaaacatca tgcaatatgc gaaacctgtc actctgaatg
     4381 ttgaagagtg cgaccgtctc tcctttctgc cgtatctgtt tggcaacgat tttctgtatg
     4441 ccgaggcgta tgtgtacgcg ctggcgcaaa aaatgatgcc ggaatatcag ggaggcttct
     4501 ggcacttcat ccgcctgccg gacggtggcg gttacatgat gccggatggc gaccgtttcc
     4561 acatggtgaa cggtgcaaac tggtttgacc gtaccgtgag tgctgatgcc gcaggcatca
     4621 tcctgacctc ccttgtgatt aaccgccagt tgtggctgta ccacgacagc ggggatgcag
     4681 gactgaccca gctttaccgg atgcgcgatg cgcagttgtg gcgtcacatc gaatttcacc
     4741 ccgaatgcaa cgcgatttac gcggctctgg actgattaac ggacggggcg gcaatgccgc
     4801 ccctgtaaag gagacgagaa catgtactgt actgttaaag aaattatccg cgaagtgctg
     4861 gatacagacg tgccggacag tgaatgcgtt tttgccgtag tgctgacccg tggggatgtg
     4921 cgtcacatag cccaggactg gagtctgaca gacgatgagc tggaaaccgt catgcagcgg
     4981 ctggacgatg cctttgaata tggtgcggat gtcagcgttg ttcacggcgt tgttcgtgaa
     5041 ctgatggaag aaaagcgcgc cagccgtcag gtgacagtcc cggcggtgat gctggaaaaa
     5101 gtgatggcgc tggcaggcag tgaaatgaag cgcctgtatg ccgtcgggag tgagaacggg
     5161 ggcgacggtg acgcattcgt cagggaggaa cgcgaagcaa tggacgttgt gttacaggcg
     5221 ctggacgggg agacgatgtc atgaatatca gcacagaaac ccgcgaaatt ctgcgtaatt
     5281 acagggccgt gattaatgcg cggcgtcgtg aaatggggca gaaaccgctc accaccgcgc
     5341 agattgttga tgaaatctgc gattttgtgg cgaatcagca ggcggttttc ctgggcggtc
     5401 actacatctt acagggtagc agaaacaggt gatacagggg caggcggtgg aggccgcctg
     5461 tcagtccgcg cgaaaacccc tggcaggctg acgcctgccg gaagggaagc gggccacgct
     5521 ggcgcgtcgc ccgttaccct tcccgtctgt gatgtgtctg actcaggagt gtttctttct
     5581 tatgttatgg aactgttcct gatgttgttg ttcctttatc tgctgctctg attctgacta
     5641 ctgcagtgtt gttctgtctg ccgggcgcac cttcggctcc cggctgcctg gcggcatccg
     5701 gtcgtcaggc ccgactccga caggcagctg ctggcgcacc cgccagtctc cgccgaaccc
     5761 gctggcgcgg tttcgggctg tcgctacggt ccgatgcgtg aaaaccccgg gcttgcagcg
     5821 accgttccgg tcgcgccacc cttgtcgcgc cgtggcctgc gctcccggca tcccggcaaa
     5881 aggccgccgg gatgtaaggg gcaacgccgt ttcgcgcacg cgctctccgt cgttgcggcg
     5941 ggtccctgct cattgcctgc cggtgccaca cacccgtatg agtccctgtc gcctggggct
     6001 gatacagcca caacctgccg cactgactgt ccagggtaaa tgaacagccc acaaaatttt
     6061 ttacccaaaa cccggtaaaa aattttgcgt tctgcccagg acaggtgcgt caggccgtgg
     6121 cagtgatgcc ccttgcggcg aaggttctca aacgggtgaa gttcatacca cagggtatac
     6181 agcagcaggt tcccgcgaaa cgtcaaaacc gcggctcccg aaactcaacg ggtgatgttc
     6241 tttaaaaatc aggatttatt tcaggctccg gcaatacgca tttatgtgtt ctgtcagtca
     6301 tccggctggc aggtaatgag aacgcaggaa cagaaggagg aaaacaccgg agaacgtcag
     6361 acgcagatat gaaaaaagca ggtcagggac ctgcttaatc cacaccgcag agactgcacg
     6421 aacagtcttt acggtttcat taattaacgt cataagaggc taaattatga cagtaagtat
     6481 tgtttcacct tccgcagcgg ctgtaaagcc ccgccgtcat ccccgtttca gacgcgaaga
     6541 catccccgcg ccggaaattg accccgtgct gaaagccttc gggcgacaca ttgcccggag
     6601 ttttcaccgg gggcgtggtg tacacatccc cgccatgaaa aacacggcct tcgggcaggt
     6661 gctccgcaca ctcgaactga aacgcgcttt taactgatga ggtgagccgc cccgcgaggg
     6721 gcggcaacag acggaaggag aacattttat gacattagca gcaatcacca tgaccgcccc
     6781 ggaagccgcc agccctgtgc agatgtaccg cgcgacctac tcaccggatg acaacaaact
     6841 gcgcctgtat gccgtgtcac gtcttgaccc ggagacgtat aaaaaagtgc atgatgccgg
     6901 tttccgctgg gcaccaaaac aggcgctgtt tgtcgcgcca gcctggacac cgggccggga
     6961 agacgtgctc ctctcacttg ccggagagat tgaggatgaa gacagcacgc tcgctgaacg
     7021 tcaggaagca cgggcggagc ggtttaccgg atacagcgga aagcgggcca gtgaatccgc
     7081 acaggcactt gatgaagtgg aaagactggc cgcgatgatc ccgcccggtc agcccattct
     7141 tgtggggcat cacagcgaac gccgcgcccg tcgtgatgcg cagcgtattg aaaacggcat
     7201 gaaacgagcc gtgatgctct ttgaacgtgc ggaatactgg gaagagcggg cgcggtcggc
     7261 actgcttcac gcgaagtata aagaacgtcc ggacgttcgc tggcgtcgta tcaaaaaaat
     7321 cgaagctgat ttgcgcaagg ctgaaaagac catcgcgcag tcgcagaaat atctgacgat
     7381 gtggcgggct gaatcgctgg atctgaatat ggcaaaactc atcagcagtc atgaccatat
     7441 cagcgcctgt ttcccgctgg atacgtatcc gcgcccggca gaaaaaagcc agtatgaagg
     7501 aagtcgatcg ttatggtcgg ccctggatga tgacatcatc accacggagc aggcccgcga
     7561 aattgcgatc cgctgtcatg aacggcagat tcagcatcaa caacgctggg ttaaccacta
     7621 tcagaaccgc ctgatctatg agcgtgccat gctggacgaa agcggcggcg tggttacccg
     7681 gacacaggat tttgagccgg gcggacaggt tttcagccgg ggcgagtggc tgaccatcat
     7741 ccgtgtgaac aaaagcaacg gggcggtgag ttcagtcaca acgccaaatt acagttttct
     7801 cgggtacagc ggcacgatga aagtgacgcc cgatcgcatc acggactaca aagcaccatc
     7861 ggcagaagag gctgccgtcg ccagtcaggc cgcgaagcgt ccgccggtag tcaactatcc
     7921 gggggaaggt ttccgggaaa tgacaaaggc acagtgggcc gccctgcccc gggactgtaa
     7981 ggccgtgcgc agtgtggcag aagcagaaga ccacggggca taccggtacc gccgcacaat
     8041 ggacaataat ttccgcctgg tgaatgtgta tatctccgac atgaaaatca cggaaatccc
     8101 acagaaataa ggtatatccc cccgggaaaa tccccggggg atgacggaga taatgatatg
     8161 cacagtcagt taagagaacg tatccggctg atgcgcgcaa ggctggataa cgccgcgccg
     8221 gttgctgaaa tccgggctga atctcagctt tttgtgactc ctgccccggt ctgtgatcgc
     8281 ctggtgatgc tggcggagat cagcaaccgt gatcacattc tggaaccctc tgccggcacc
     8341 ggggccatac tgcgggcgat tcgggatacc gcgccggggg ccatgtgtga tgcggtggaa
     8401 atcaacagcg ggctggtccg gtatctgcgg gaaaatttta acggtgtcag ggttcagtgt
     8461 ggcgacttca tggaatggct gccggtgcag tattacagcc gggttatcat gaatccgccg
     8521 ttcagccacg ggcaggatat ccggcatatc ctgcgggcct tttccctgtt gcgtccgggt
     8581 ggcgtgctgg tcgccgtctg tctcaacgga ccacgccagc aggagaagct gttaccgttt
     8641 tctgacgtcc gcgaggagct gccgcgcggc acgtttgctt ataccgatgt cccgacgatg
     8701 attattcgtc tgcgtgcctg atgacacagg gccggcggga ggataaatgc ctgtctgccc
     8761 gcgccgggaa aaaacgcgcg ccggtggcgc tgaaaggggc cgcgctcacg cgccgcccct
     8821 ttcattacgc ggacgttctg atgggggctt ctgtttcttc atgcctgtca tttgtctgtt
     8881 actgatgttg ttgtt
//
LOCUS       DACAOP010000142         8857 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.142, whole genome shotgun sequence.
ACCESSION   DACAOP010000142 DACAOP010000000
VERSION     DACAOP010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8857
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.142"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(63..1145)
                     /locus_tag="IT892_004099"
     CDS             complement(63..1145)
                     /locus_tag="IT892_004099"
                     /inference="COORDINATES: protein motif:HMM:NF037421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137239.1"
                     /translation="MAETEHFDTEQLEKTYADAVNNVIKLRRDLKGYEETNNQEAIDQ
                     TNEQIAELKSIQNTTFNALGYVPQFDDLENEEEAIPDELKMFAQQEDNKSFTAAVVSP
                     ANDEPAIPAPVHSSAEPTEEELFPVEPKDNGFTDKAPVAAMTVANDDPEPAVKDTTEQ
                     DILELEELHNANKGQSFNSKTRFLDDEDYHRLFDNVGRIGRSLDGQKRIVYFKDNTQL
                     LEKTDSIVVMARNQIDSARRLVLVAKEKGWNTVTFQGNSSFLENAYLQAVQNGVGVKP
                     LSEEQRQFYKEVHDRFKLDELNIPFLGKKSLKELEDEKKERELAKVSNAEPEKKPDIK
                     QQQKEPETPKPENKPDENKPRRKFKR"
     gene            1314..1940
                     /locus_tag="IT892_004100"
     CDS             1314..1940
                     /locus_tag="IT892_004100"
                     /inference="COORDINATES: protein motif:HMM:NF013793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP3137240.1"
                     /translation="MIPYSVWNFKGGVGKTHTSLTLSGHLASQGKRVALVDYDPQNGA
                     TICSDIAKANGSPLPFLVVKSLSEINRDEIDAVVFDHSPGVNPGGQLAPIVIVPTILD
                     AASHSITIKSVHELDGTDKLCIVIPNRVELQNREHKDLLEMQFENVPYMKKRVSYSRA
                     YGMGVTIYSEGTGLPNLGITRQEFDGVAKYIHKRIEKHIADMKAKEKA"
     gene            1944..2279
                     /locus_tag="IT892_004101"
     CDS             1944..2279
                     /locus_tag="IT892_004101"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137241.1"
                     /translation="MSKKKNSWLDDMQSFEKIAVETAFNAGDSYWSHEYFAHSNNAAH
                     VVTNVKIRAKEDETRLTNIRIPAQLEAVLAQIAPGVPIATALLVLADLKASELVKENK
                     AVKISNKGE"
     gene            2427..4373
                     /locus_tag="IT892_004102"
     CDS             2427..4373
                     /locus_tag="IT892_004102"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137242.1"
                     /translation="MAQPKQSVNAKGLKEYNHKGFLASNSGANNVDSPLYPAIGDAMF
                     FDAVSTVTVTDSNPAKLVLDIEEGVYADVKPQTKYYYNELKIQGVLGGKAVNKNKEAL
                     HDQHEGEHFVLYLDGIPHHQQQLAVEIAFRVVTHPHYFIKKEQGKNRPPQWQAHIGTQ
                     SALIWGIHRGQKDYTGQNIVPDHVHIFRSMQCISDKNYIVDFQNGRPKAVIDAINPNR
                     RNVLPSMSLARNDIKASVQEQINEAWAKAGIDAKVNFGTLQDPIGVASVIKSQQITTE
                     AEENNEPVAEIAQKHINDQSLSEEDISDSLNNLGNLDEESIEKLETIIKKTAFDSVQQ
                     VKLKQSRIKDLMAEIVKEEQELQAINKGILYEAKYIHAKNLLNETSRKLESVNKELEE
                     ANKLNDDFNEKIIENTNTISNLNDELARERKYNEEQELQLNQLETELETERNINTENS
                     ELITTLTDKNAVLAANLEVEQEKTAELTAENAELKEKHKVEIATLRSEFAQKLVKYRK
                     NFVARVKNKVATAVEHAIQAFRDNELPSLLKDATTKAVSEYKLKELPGKLRKVREEEA
                     KKSEKEIKALTNDVSTLKTNVNTLTADKDTLQKDFDELFNASKEKATEMNNEIARLKE
                     ILKSNGINPDGDNSPKKPKNDNKI"
     gene            4384..5124
                     /locus_tag="IT892_004103"
     CDS             4384..5124
                     /locus_tag="IT892_004103"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137243.1"
                     /translation="MNINNNKDRIKEIESLGVSGEETPLTPPDGIVGAINELREEENT
                     LPDPLFVGKLVNPLIMKDKPGYAKKMKARKHITFKPNEDGLDLLECYYNDFYIELYTR
                     DYNEHLQAIPKKNLEKLARVDKKFQTYLEETEYTFYENISELFDLFGDTIYEWGMATP
                     SVDSSVIFTKAVLTEAVLRNMPVYPDLMNEQQRRILRRLFISIKDEYKMVYHSEMTKE
                     VRTTHYICGKNYYESMSKNKSYLLSSGY"
     gene            5208..7538
                     /locus_tag="IT892_004104"
     CDS             5208..7538
                     /locus_tag="IT892_004104"
                     /inference="COORDINATES: protein motif:HMM:NF017826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HAP3137244.1"
                     /translation="MTTNKIEVFLVRDGDIDYDSISENVVSDEVEQEEEQLQNEENNL
                     DNESEYEEEYQEDDEYTEEEDDQNDEHHASTVIGEAQEAGSDDPSNKLDGLPSPIRRK
                     KKEKEITLYESFVGKITTHGMYHTSRKSVKGKVVVKDILVHNFPIIPVEIITALDGTT
                     DESVTYIKFVFKSIDGEFKEVIIPSGAANDFKEVKKAGFLAPSPLNHSKVLALINDVI
                     SNGSLNKKAGYSQCGWTNDLMHHIRPDNDLYVGKKVKVTETKGSADLYFSMLSEFVLS
                     CPQMAFGLAFAAAGYMRGYITVTSLTPFYILYGKANEGKSKTCQLIASLQGNPMKGKG
                     NNIDWNTTMIGFHKFLANNNHGVLVVDELDNLFLKNNITHAATLIMDITNGGGRAYSD
                     QYRNTHQGESWNNSVIASTNLRIEDVAGGTMKEQALFTRLMQIDVLDPVLHNYKGGQY
                     RLEQLSQIMSENYGHFYPKAIEQIKIKGKEYKARLNELLKELTTDIKLVDLQNEPRSL
                     EMLALAQVGAELVGDVLGEKEGAACQAAVDIIIERFKRSEDELISKKQNEDANTYEML
                     KSFITDNAQRFRWENYAYCQGNRLDMKKSQIDQAIEFSSNATKASTGALGVVVQESVM
                     DHALDYKGYVLLNPSAFDSLARYGISKDKIISAAKNLGMLREQGGKNTKKLSDKYRTM
                     LSGLSRAYKIELKDISDILEFEVPEVAPEENLKEITPVKESDFTTEHLSENGNGQLSP
                     EIEQQLDRIMEDYDKFGFTDWDNIGASIQNKTNKGE"
     gene            7541..7801
                     /locus_tag="IT892_004105"
     CDS             7541..7801
                     /locus_tag="IT892_004105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137245.1"
                     /translation="MKDRYTLNQGRNALIDSEADQPVRIFFTNNVYVCKTPTGMFKER
                     SPEELARLLNRTANQQKVSAGFKLGRPRTADELSKLLEKNQK"
     gene            complement(7849..8100)
                     /locus_tag="IT892_004106"
     CDS             complement(7849..8100)
                     /locus_tag="IT892_004106"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137246.1"
                     /translation="MTTSHDLSTILMAWGVLFLCVWLTKHYTRLELSNILTSGKVSIQ
                     YVVANLAYRAGFIALVVACLASLAVSIGFSVGYFGSYYP"
     gene            complement(8189..8599)
                     /locus_tag="IT892_004107"
     CDS             complement(8189..8599)
                     /locus_tag="IT892_004107"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137247.1"
                     /translation="MKTKFSQKLRQYHYNEKKLRRRYIEFCILCYVSYTVLIATVVFG
                     FLAEDIFQLYSAVIFGLIMSTLTFRFSLMAYGVKYQTTYTHGFFRTPGEWLPDFSYNT
                     VWKEEWNEEPIDMLAIKETKSLPNKKSNSFNDIM"
     gene            complement(8589..>8857)
                     /locus_tag="IT892_004108"
     CDS             complement(8589..>8857)
                     /locus_tag="IT892_004108"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137248.1"
                     /translation="MSNKEKDLAFKIISRKAFDIKHMIAKIEKRRMQLFVPEKTLEEI
                     QCLLPELYKIHSIPALIDYAIDLKQKSGSVFLFECNQEGEHYEN"
BASE COUNT         3011 a         1535 c         1731 g         2580 t
ORIGIN      
        1 aagcaattat attacggggt tatacataaa aaaagagagc tatttaagcc ccctttataa
       61 ctttatcttt tgaattttct tcttggtttg ttttcatcgg gtttgttttc tggtttaggt
      121 gtttcaggtt ctttttgctg ttgtttaatg tcaggctttt tttctggttc ggcattactg
      181 actttcgcta actccctctc ctttttttcg tcttcaagtt ctttaagaga tttttttcct
      241 aaaaacggaa tatttaattc atcaagttta aacctgtcgt gaacttcttt ataaaactgt
      301 ctttgttctt cacttaatgg cttaaccccg acaccgttct gaacagcctg taagtaagca
      361 ttttcaagaa aagaagaatt tccctggaaa gtaaccgtat tccagccttt ttccttagcg
      421 acaagaacga gtcttcttgc actgtcgatc tgatttctcg ccatgacaac aatagaatcg
      481 gttttttcaa gcaattgagt attgtctttg aagtaaacaa ttcttttttg cccatcaagt
      541 gatctaccaa tacgacctac attatcaaaa agcctgtgat aatcttcgtc gtccaggaag
      601 cgggttttag aattgaatga ctgccccttg tttgcattgt gaagttcttc cagttcaaga
      661 atatcctgtt ccgtagtgtc cttaacggca ggctctggat cgtcgttcgc cacggtcata
      721 gctgctactg gtgctttgtc agtaaagccg ttgtccttcg gctccacagg gaagagttct
      781 tcttctgttg gttctgcact gctatggact ggtgcgggta tggcgggttc gtcatttgcc
      841 ggtgatacaa cggcagcggt aaagctttta ttgtcttcct gttgagcaaa cattttcagt
      901 tcgtcaggta ttgcttcttc ttcgttttcc aggtcgtcaa actgtggaac atagccgaga
      961 gcattaaatg ttgtgttctg tatgctttta agctctgcta tttgttcgtt agtctggtca
     1021 atcgcttcct gattgtttgt ctcctcatat cctttcagat ctcttcttaa cttgatgaca
     1081 ttgttaacgg catcagcata agttttttca agctgttcgg tgtcaaagtg ttctgtctct
     1141 gccataggca actccttagt tatcgttatg tttttaattt agatgatttt tttgcacaaa
     1201 ccctctacaa tgtagtatag tatattatag catattggca atagctgacg gctaaaaaat
     1261 gttcatgggt gattccatga aatttcttta taaacatcat gttagggggt tttatgattc
     1321 cgtattcagt atggaacttc aagggaggtg ttgggaaaac tcacactagt ttaactctct
     1381 ccgggcatct ggccagtcaa ggtaaacggg tggcacttgt tgactacgac cctcagaacg
     1441 gggctacaat ctgttcagat attgccaaag caaatggaag ccctttaccg tttttggtgg
     1501 taaaaagcct gagtgaaata aaccgcgacg agatagatgc agttgtcttt gaccattccc
     1561 caggtgttaa ccctggtggt cagcttgccc ctatcgttat cgttcctacc atcctcgatg
     1621 cagcaagcca ttctatcact atcaaaagtg ttcacgaact ggacggaacg gataagctct
     1681 gtatcgtcat tccaaaccgt gtagaactgc aaaacaggga acataaagac cttctggaaa
     1741 tgcagtttga aaatgttccc tacatgaaga agcgagtctc ctactctcgt gcctacggta
     1801 tgggtgtaac tatctattca gaaggtacgg gcttaccgaa cctggggatc actcgccagg
     1861 agttcgacgg ggtagctaaa tacattcata aacgaatcga aaaacacatt gctgatatga
     1921 aagcaaaaga gaaggcataa cttatgagca agaaaaaaaa ctcatggctt gacgatatgc
     1981 agtcgtttga aaagattgcc gttgaaactg ccttcaatgc gggtgactct tattggtcgc
     2041 atgaatactt tgcacatagc aataatgctg ctcatgtcgt cactaatgta aaaatacgag
     2101 caaaagaaga cgaaacccgt ttaaccaata ttcgtattcc tgcacaactg gaagcggttc
     2161 ttgcacaaat cgcccccggt gttcctatcg ctacggcttt attggtactt gcagatttaa
     2221 aagccagcga gcttgtaaaa gaaaataaag ctgtaaaaat atcgaataaa ggggagtaac
     2281 ccttatgtca ggtaattaca agttaagtcg tcagttcgtc ggaaatataa caggtgacac
     2341 ttttattttt tgagaaatag aatattatgg attaagatag atttgaaatc tatttttcta
     2401 ttaaaaaaat aactaaggag ttacatatgg cacaaccaaa acaatctgta aatgcaaagg
     2461 gtttaaaaga atataatcac aaaggtttcc ttgcttcaaa ctctggtgct aacaatgtag
     2521 atagcccgct ttaccccgct attggggatg caatgttttt tgatgcagtt tcaacggtta
     2581 ccgtaactga tagcaatcct gcaaagttag ttctcgatat agaggaggga gtttatgctg
     2641 atgttaaacc ccaaaccaaa tattattata atgaacttaa aatacagggt gtacttggcg
     2701 gtaaggcagt aaacaaaaac aaagaagctc ttcatgatca acatgaaggt gaacattttg
     2761 ttttatatct tgatggtatt ccacaccatc agcaacaatt agcagtagaa atagctttta
     2821 gagtagtaac tcaccctcac tattttataa aaaaagaaca aggtaaaaac agacctccac
     2881 aatggcaagc acatatagga acacaaagtg ctcttatatg ggggattcat cgtggtcaaa
     2941 aagattacac tggtcaaaac attgttcctg accatgttca tatatttaga tcaatgcaat
     3001 gtatatcaga taaaaactat attgtcgatt tccagaacgg aagaccaaaa gcagttatag
     3061 atgctattaa tccaaataga cgaaatgtat tgccatctat gtcgttagct cgcaacgaca
     3121 taaaagcatc agttcaggag cagattaacg aagcatgggc gaaggctggt atagatgcaa
     3181 aagttaactt cggaactcta caagatccta tcggtgtagc ttccgttatt aaatctcaac
     3241 aaataactac cgaagcagaa gagaataacg aacctgttgc agaaattgca cagaagcata
     3301 tcaatgatca atctcttagt gaagaagata tttcagactc attgaataat cttggaaacc
     3361 ttgatgaaga atctattgaa aaacttgaaa caattattaa gaagacagca tttgatagtg
     3421 ttcaacaagt taaattgaag cagtctcgca ttaaagatct tatggcagag attgttaaag
     3481 aagaacaaga attacaggct attaataaag gcattcttta tgaagctaag tacattcatg
     3541 ctaaaaacct gttaaatgaa acttccagaa agcttgaatc tgtaaataaa gaacttgaag
     3601 aagcaaataa actaaatgac gatttcaatg aaaaaatcat tgaaaatacg aatactattt
     3661 ctaaccttaa tgatgaatta gcgagggaaa gaaaatataa cgaagaacaa gaattacaac
     3721 ttaaccagtt agaaacagag cttgaaaccg aaagaaatat aaatacggaa aattccgagc
     3781 ttattacaac ccttaccgat aagaatgctg ttttagcggc taatctggaa gttgagcaag
     3841 agaagacagc agagctaaca gccgaaaatg cagaactcaa agagaagcat aaagttgaga
     3901 tcgctactct tcgtagtgag ttcgctcaga aactggttaa ataccgtaaa aactttgtgg
     3961 ctcgtgttaa aaacaaagtg gcaacggctg ttgaacatgc aatacaggca tttagagata
     4021 atgaattacc ttcattactt aaagatgcaa caaccaaagc tgttagtgaa tataaattaa
     4081 aagaattgcc tggaaaactt agaaaagtaa gagaggaaga agccaaaaaa tcagagaaag
     4141 aaattaaagc attaacaaac gatgtttcaa cgttgaagac taatgtaaat actttaacgg
     4201 ctgataaaga tacattgcag aaagattttg acgaattgtt taatgcaagc aaagaaaaag
     4261 caacggaaat gaataatgaa attgctcgtc ttaaagaaat tcttaaaagc aatggaataa
     4321 accctgatgg tgataactca ccaaaaaagc ctaaaaatga caataagata taaggggtga
     4381 cttatgaaca taaacaacaa taaggacaga ataaaagaaa tagagagtct tggtgtaagc
     4441 ggggaggaaa ctccccttac tccacctgat ggtattgtag gagcgattaa cgagttaagg
     4501 gaagaagaga acactcttcc cgatcccttg ttcgtcggca agctggttaa tcctctcatt
     4561 atgaaagata agccaggtta tgctaaaaaa atgaaggcaa gaaagcatat tacttttaaa
     4621 cccaatgaag acggtttaga tttgcttgaa tgctattata atgatttcta tatagagctt
     4681 tatactcgtg attataatga acatttacag gctattccaa aaaagaattt agaaaagctt
     4741 gcaagagtcg ataagaaatt ccaaacctac ctggaagaaa ctgaatacac attttacgaa
     4801 aacatatctg aattatttga tttattcggt gatactattt atgaatgggg aatggctaca
     4861 ccttcggtag atagcagtgt tatattcaca aaagctgttt taacagaggc tgtattaaga
     4921 aacatgcctg tctatcctga tttaatgaat gaacaacaaa gaagaatttt aagaagatta
     4981 tttatcagta ttaaggatga atacaaaatg gtttaccatt cagagatgac aaaagaagta
     5041 agaacgacac actatatttg tggtaaaaat tattatgagt ctatgagtaa aaataaaagc
     5101 tatttattat catcgggtta ttgacacttt aataaaaatc gaacatagtt tataatatac
     5161 attgaaatat acagataaat atataagaaa gaaaaaacgg ggtgcttatg acaacaaata
     5221 aaatagaagt tttccttgta agagatggtg atattgatta cgactcaata tctgagaatg
     5281 ttgtatctga tgaagttgag caggaagaag aacagcttca aaatgaagaa aacaatcttg
     5341 ataacgaatc tgaatatgaa gaagagtatc aggaagacga cgaatatacg gaagaagaag
     5401 acgatcagaa cgacgaacac catgcttcga ctgtaatagg agaagcacag gaagctggtt
     5461 cagatgatcc gtccaacaaa ctggacgggt taccttctcc tatacgcagg aagaaaaaag
     5521 aaaaagaaat aactctctat gaaagttttg tagggaaaat tactacacat ggtatgtatc
     5581 acacttcaag aaaatcagtg aaagggaaag ttgttgttaa agatattctt gttcataact
     5641 tcccaattat tccagtggaa attattacgg ctctcgatgg gacaactgac gaatcagtaa
     5701 cttatattaa atttgttttc aaaagcatcg acggcgaatt taaagaggtt attattcctt
     5761 ctggtgctgc taatgatttc aaagaagtaa aaaaagcggg ttttcttgca ccgtcgccat
     5821 tgaaccattc aaaagtgctc gcacttatta atgatgtcat ttctaatggt tcattaaata
     5881 aaaaggctgg gtattcacaa tgtggctgga caaatgattt aatgcatcat atcagaccag
     5941 ataatgatct ttatgtgggt aaaaaagtaa aagttaccga aacaaaagga agtgctgatt
     6001 tatatttttc tatgctttcg gaatttgttt taagttgtcc acagatggct tttggtcttg
     6061 catttgcggc ggctggctat atgcgtggat atattacggt aacaagtttg acgccttttt
     6121 atattcttta cggtaaagca aatgagggta aatctaaaac ttgtcagctt atagcaagct
     6181 tacaaggaaa cccaatgaaa gggaaaggta ataacatcga ctggaacact actatgattg
     6241 ggtttcataa atttcttgca aacaataatc atggtgtttt agttgttgat gaattagata
     6301 acctttttct taaaaataat attactcatg ctgcaacatt gattatggat attacaaacg
     6361 gtggtggtcg tgcttactct gaccaatatc gaaataccca tcagggtgaa agctggaaca
     6421 attctgttat tgcttctact aaccttcgta ttgaagatgt tgcaggtgga acgatgaaag
     6481 aacaagcttt gttcactcgt ttaatgcaaa tagatgttct tgacccagtt ctgcataatt
     6541 acaaaggtgg tcaatacaga cttgaacaac tcagtcagat catgagtgag aactacggtc
     6601 atttttatcc aaaagcgata gaacaaatta aaatcaaagg taaagaatat aaagcaaggc
     6661 ttaacgaact gttaaaagaa ctgaccactg acattaagct tgttgacttg cagaacgaac
     6721 ctcgttcact ggaaatgctg gctcttgctc aggttggtgc tgaactggtc ggtgatgtat
     6781 taggtgagaa agaaggtgca gcttgtcagg cagcggtaga cattatcatt gaacgattca
     6841 agagatcgga agacgaactt atatctaaaa agcaaaatga agatgctaac acttatgaaa
     6901 tgttaaaaag tttcataacg gataatgctc aaagattccg ttgggaaaat tatgcttatt
     6961 gccagggcaa tcgcttagat atgaaaaaat ctcagattga tcaggcgatt gaattttcca
     7021 gtaatgcgac aaaagcaagt accggtgcat taggtgttgt tgtacaggaa tcggttatgg
     7081 atcatgctct tgattacaaa gggtatgtat tacttaatcc gagtgcattt gatagcctcg
     7141 ctcgttatgg tatttcaaaa gataagataa tttcagcagc taaaaatctt ggtatgttga
     7201 gagaacaggg cggtaagaac actaaaaaac ttagtgacaa gtatagaaca atgctttctg
     7261 gtttaagtcg tgcttacaaa attgaactta aagacattag cgatatcctg gaatttgaag
     7321 taccagaagt tgcaccagaa gaaaatctga aggaaatcac cccggtgaaa gagtcagatt
     7381 tcacgacaga gcacctttca gagaacggga acgggcaact ttcacctgaa attgaacaac
     7441 agttagacag aatcatggaa gactatgaca aattcggctt tacggattgg gataacatag
     7501 gagcttccat acaaaacaaa accaacaaag gagagtgatt atgaaagaca gatataccct
     7561 taaccagggc agaaatgccc ttatagacag tgaagcagat cagccagtca ggattttttt
     7621 cactaacaat gtttatgtgt gcaagactcc aacaggcatg tttaaggagc gaagccccga
     7681 agaactggca agactgctta accgaacggc taaccagcaa aaggtatcgg cgggttttaa
     7741 gttaggaaga cccagaacgg cagacgaact atcgaagctg ttagagaaga accagaaata
     7801 acaaagcccc taaaaagggg ctttttaacg gcttatagga gagtgttttt aagggtaata
     7861 agaaccgaaa tacccgacag aaaacccgat tgacaccgct aacgaagcca ggcaagcaac
     7921 aaccaaagca atgaagccag cacgataagc aaggttggca acaacatatt ggatagaaac
     7981 ttttccagaa gttagaatat tactaagttc taaacgggta taatgcttag taagccatac
     8041 acataaaaac aatacacccc atgccattaa gatagttgat aaatcgtgtg aagtagtcat
     8101 tttatttctc ctataaaccg tttgttcatt attaatttag cgtactcttt tttgtatctc
     8161 aagttttttt tcgatgtttt tcatcatctt acataatgtc attgaagctg ttagattttt
     8221 tgttaggtaa tgatttggtt tcttttattg ccaacatatc aataggttct tcattccact
     8281 cttctttcca gacggtattg taagaaaaat caggaagcca ttcacctggg gttctgaaaa
     8341 aaccatgagt gtaagttgtc tgatacttta ctccatatgc cattagacta aatctgaatg
     8401 tcagagtaga cattatcaaa ccaaaaataa cagcagagta caactggaat atatcttccg
     8461 ctaagaatcc aaaaacaacc gttgcgatca agacagtata tgaaacataa caaagtatgc
     8521 aaaactctat atatcttctc cttaattttt tttcattata atgatactgc cttagtttct
     8581 gtgagaattt agttttcata atgctctcct tcctggttac actcaaataa gaatacactt
     8641 ccactctttt gtttcaaatc aatagcataa tcgataagtg caggtattga atgaatttta
     8701 taaagctctg gtaataaaca ctgtatctct tcaagagttt tttctggaac gaataattgc
     8761 attcttcttt tttcaatctt tgcgatcata tgtttaatat caaaagcctt tcttgatatt
     8821 attttgaaag ctaaatcctt ttctttgtta ctcattg
//
LOCUS       DACAOP010000143         8820 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.143, whole genome shotgun sequence.
ACCESSION   DACAOP010000143 DACAOP010000000
VERSION     DACAOP010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8820
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.143"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            236..757
                     /locus_tag="IT892_004109"
     CDS             236..757
                     /locus_tag="IT892_004109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP3137249.1"
                     /translation="MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQD
                     TFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPE
                     ERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKA
                     VEHCLLFRLEYGL"
     gene            754..1707
                     /gene="fecR"
                     /locus_tag="IT892_004110"
     CDS             754..1707
                     /gene="fecR"
                     /locus_tag="IT892_004110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fec operon regulator FecR"
                     /protein_id="HAP3137250.1"
                     /translation="MNPLLTDSRRQALRSASHWYAVLSGERVSPQQEARWQQWYEQDQ
                     DNQWAWQQVENLRNQLGGVPGDVASRALHDTRLTRRHVMKGLLLLLGAGGGWQLWQSE
                     TSEGLRADYRTAKGTVSRQQLEDGSLLTLNTQSAADVRFDAHQRTVRLWYGEIAITTA
                     KDALQRPFRVLTRQGQLTALGTEFTVRQQDNFTQLDVQQHAVEVLLASAPAQKRIVNA
                     GESLQFSASEFGAVKPLDDESTSWTKDILSFSDKPLGEVIATLTRYRNGVLRCDPAVA
                     GLRLSGTFPLKNTDAILNVIAQTLPVKIQSITRYWINISPL"
     gene            1794..4118
                     /gene="fecA"
                     /locus_tag="IT892_004111"
     CDS             1794..4118
                     /gene="fecA"
                     /locus_tag="IT892_004111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate transport protein FecA"
                     /protein_id="HAP3137251.1"
                     /translation="MTPLRVFRKTTPLVNAIRLSLLPLAGLSFSAFAAQVNIAPGSLD
                     KALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSW
                     TLEPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRI
                     PGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPIS
                     LGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPK
                     ETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLL
                     QYYDGEADMPGGLSRADYDADRWQSTRPYDHFWGRRKLASLGYQFQPDSQHKFNIQGF
                     YTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYVNESTHE
                     MRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQ
                     NNAITGTHEEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVE
                     PEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTNDTVTARGKTRHTGLETQAR
                     YDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTF
                     NLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKN
                     IFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF"
     gene            4163..5065
                     /gene="fecB"
                     /locus_tag="IT892_004112"
     CDS             4163..5065
                     /gene="fecB"
                     /locus_tag="IT892_004112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter
                     substrate-binding protein FecB"
                     /protein_id="HAP3137252.1"
                     /translation="MLAFIRFLFAGLLLVISHAFAAMVQDEHGTFTLEKTPQRIVVLE
                     LSFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDL
                     IIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQH
                     KERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGSSMPS
                     IGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRG
                     IFAAERIAADTVKIFHHQPLTVVK"
     gene            5062..6060
                     /gene="fecC"
                     /locus_tag="IT892_004113"
     CDS             5062..6060
                     /gene="fecC"
                     /locus_tag="IT892_004113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate ABC transporter permease FecC"
                     /protein_id="HAP3137253.1"
                     /translation="MTAIKHPMLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALL
                     PGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAA
                     LAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALS
                     AFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQL
                     NLLNLSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAG
                     FDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG"
     gene            6057..7013
                     /gene="fecD"
                     /locus_tag="IT892_004114"
     CDS             6057..7013
                     /gene="fecD"
                     /locus_tag="IT892_004114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter permease
                     subunit FecD"
                     /protein_id="HAP3137254.1"
                     /translation="MKIALVIFITLALAGCALLSLHMGVIPVPWRALLTDWQAGREHY
                     YVLMEYRLPRLLLALFVGAALAVAGVLIQGIVRNPLASPDILGVNHAASLASVGALLL
                     MPSLPVMVLPLLAFAGGMAGLILLKMLAKTHQPMKLALTGVALSACWASLTDYLMLSR
                     PQDVNNALLWLTGSLWGRDWSFVKIAIPLMILFLPLSLSFCRDLDLLALGDARATTLG
                     VSVPHTRFWALLLAVAMTSTGVAACGPISFIGLVVPHMMRSITGGRHRRLLPVSALTG
                     ALLLVVADLLARIIHPPLELPVGVLTAIIGAPWFVWLLVRMR"
     gene            7014..7781
                     /gene="fecE"
                     /locus_tag="IT892_004115"
     CDS             7014..7781
                     /gene="fecE"
                     /locus_tag="IT892_004115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter ATP-binding
                     protein FecE"
                     /protein_id="HAP3137255.1"
                     /translation="MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTL
                     LNCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRN
                     PWLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVV
                     LLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMA
                     QGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR"
     gene            complement(8339..8596)
                     /locus_tag="IT892_004116"
     CDS             complement(8339..8596)
                     /locus_tag="IT892_004116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137256.1"
                     /translation="MTLVNDTGFDPVFSGSIAESWRQQPCTPSYCCDWEAATMLRAFP
                     LAKKGEGRARLPSLYASFGKLGETPTHEDIIDNNRSINWPV"
     gene            complement(8679..>8820)
                     /locus_tag="IT892_004117"
     CDS             complement(8679..>8820)
                     /locus_tag="IT892_004117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP3137257.1"
                     /translation="DAAHAITDYIVGYYSALRPHEYNGGLPPNESENRYWKNSNAEAS
                     FS"
BASE COUNT         1923 a         2513 c         2446 g         1938 t
ORIGIN      
        1 aaatccccat cctttagggc agtgaggatg tcaataatag cagaccacat catgagtcat
       61 tctgaccgac acatgccaga agcagaggct ccatcccatt ttatacctac cttataacac
      121 ttagaaaaac aacatgttaa aaatgtctat tggaaacaat tttatttcca attgtaatga
      181 taaccattct catattaata tgactacgtg ataattaact tttgatgcac tccgcatgtc
      241 tgaccgcgcc actaccacag cttccttaac gttcgagtcg ctttatggca cacatcacgg
      301 ctggttgaaa agctggctga cgcgcaaact ccagtctgct tttgatgcag atgacattgc
      361 ccaggacact tttttgcggg taatggtcag cgaaacgctc tcgacgatcc gcgatcctcg
      421 ctccttcctc tgcactatcg ccaaacgcgt gatggtggac ctgtttcgcc gaaacgcgct
      481 ggaaaaagcg tatctggaga tgctggcgct tatgccggag gggggagcgc cttcacctga
      541 ggaacgcgaa agccaactcg agaccctaca actcctcgac agcatgctgg acgggctaaa
      601 cggcaaaaca cgtgaagcgt ttctgctttc gcaactggat ggtctgacat acagcgagat
      661 tgcgcacaaa ctcggtgttt ccatcagctc cgtgaaaaaa tacgtggcga aagccgtcga
      721 gcactgcctg ctgttccgtc tggagtatgg gttatgaatc ctttgttaac cgattcccgc
      781 cgtcaggcgc tgcgttcagc ttcccactgg tatgccgtgc taagcggcga gcgcgtcagc
      841 ccacaacagg aagcgcgctg gcaacagtgg tatgaacagg atcaggataa ccagtgggcc
      901 tggcagcagg ttgaaaacct gcgcaaccag cttggcggtg tgcctggcga cgttgccagc
      961 cgggcgttgc acgatacccg cctcacccgc cgtcacgtga tgaaaggatt actgctgttg
     1021 ctcggcgctg gcggaggctg gcagctctgg cagtcggaaa ccagcgaagg tctgcgggca
     1081 gattaccgca ccgccaaagg cacagtcagc cgccagcaac tggaagatgg ctccctgctc
     1141 acgctgaata cccaaagcgc ggcggatgtg cgttttgatg cgcatcagcg caccgtccgg
     1201 ctctggtacg gtgaaatcgc cattactacc gcgaaagatg ccctgcaacg ccccttccgt
     1261 gtcctgaccc gtcagggcca gctcactgct ttagggacag aatttaccgt ccgccagcag
     1321 gataatttca cgcagcttga cgtgcagcag cacgctgtgg aagtgcttct cgccagtgcc
     1381 cccgcgcaaa aacgcatcgt gaacgctggt gaaagcctgc agttcagcgc ctctgagttt
     1441 ggcgcagtga aaccgctgga tgacgagagt acaagctgga cgaaggacat cctgagcttc
     1501 agcgataaac cgctgggtga ggtgatagcc acgctaaccc gttaccgcaa cggagtgctg
     1561 cgctgcgatc ccgccgttgc cgggctgcgc ctgagcggga cgttcccgct gaaaaatacc
     1621 gatgcgatcc tgaacgttat cgcgcaaacg cttcccgtta aaattcagtc tattacgcgg
     1681 tactggataa acatttcacc actgtaagga aaataattct tatttcgatt gtccttttta
     1741 cccttctcgt tcgactcata gctgaacaca acaaaaatga tgatggggaa ggtatgacgc
     1801 cgttacgcgt ttttcgtaaa acaacacctt tggttaacgc cattcgcctg agcctgctgc
     1861 cgctggccgg tctctcgttt tccgcttttg ctgcacaggt taatatcgca ccgggatcgc
     1921 tcgataaagc gctcaatcag tatgccgcac acagcggatt taccctctcg gttgacgcca
     1981 gcctgacgcg cggcaagcag agcaacggcc tgcacggcga ttacgacgtc gagagcggcc
     2041 tgcaacaact gctggacggc agcggactgc aggtaaaacc gctgggaaat aacagctgga
     2101 cgctggagcc cgcgcccgca ccaaaagaag atgccctgac cgtggtcggc gactggctgg
     2161 gtgatgcgcg tgaaaacgac gtatttgaac atgctggcgc gcgtgacgtg atccgccgtg
     2221 aggatttcgc caaaaccggc gcaaccacca tgcgtgaggt acttaaccgc atccctggcg
     2281 tcagcgcgcc ggaaaacaac ggcaccggca gccacgacct ggcgatgaac tttggcatcc
     2341 ggggcctgaa cccacgcctc gccagccgct cgaccgtcct gatggacggc atccccgtcc
     2401 ccttcgcccc ttacggtcag ccgcagcttt cactggctcc catttcgctc ggcaacatgg
     2461 atgccattga cgtggtacgc ggtggtggtg cggtgcgtta cggaccgcag agcgtgggcg
     2521 gcgtggtgaa ctttgttacc cgtgccattc cgcaggactt tggtatcgag gcgggcgtgg
     2581 aaggtcagct cagcccaacc tcttcacaaa acaacccgaa agagacgcac aacctgatgg
     2641 tgggcggcac agcggacaac ggttttggca ccgcgctgct ctactccggc acgcgcggca
     2701 gtgactggcg cgagcacagc gccacccgca tcgacgacct gatgctgaaa agcaaatatg
     2761 cgccggatga ggtgcacacc ttcaacagcc tgctgcaata ttacgacggt gaagccgaca
     2821 tgcccggtgg cctgtctcgc gcggattacg acgccgatcg ctggcaatcc acccgcccgt
     2881 atgaccactt ctggggtcgt cgcaagctgg cgagcctggg ctaccagttc cagccagaca
     2941 gccagcataa attcaacatt caggggttct acacccaaac cctgcgcagc ggctacctgg
     3001 agcaaggcaa acgcatcacc ctctcgccgc gtaactactg ggtgcgcggt attgagccac
     3061 gctacagcca gatctttatg atcggccctt ccgcgcacga agtgggcgtg ggctatcgct
     3121 atgtgaatga atcaacgcat gaaatgcgtt actacaccgc caccagcagc gggcagttgc
     3181 cgtccggctc aagcccttac gaccgcgata cgcgttccgg caccgaggcg cacgcctggt
     3241 atctggatga caaaatcgac atcggcaact ggaccatcac gccgggtatg cgtttcgaac
     3301 atatcgagtc ataccagaac aacgccatca caggcacgca cgaagaagtg agctataacg
     3361 caccgcttcc ggcgttgaac gtgctctatc acctgactga cagctggaat ctttatgcaa
     3421 acactgaagg ctcgttcggc accgtacagt acagccagat tggcaaggct gtgcaaagcg
     3481 gcaatgtgga accggaaaaa gcgcgaacct gggaactcgg tacccgctac gacgacggcg
     3541 cgctgacggc ggaaatgggg ctgttcctga ttaactttaa caatcagtac gactccaacc
     3601 agaccaacga caccgtcact gcacgtggca aaacgcgcca taccgggctg gaaacgcagg
     3661 cacgttacga tctgggtacg ctaacgccaa cgcttgataa cgtttccatc tacgccagct
     3721 atgcgtatgt gaacgcggaa atccgcgaga aaggcgacac ctacggcaat ctggtaccat
     3781 tctccccgaa acataaaggc acgctgggcg tggactacaa gccaggaaac tggacgttca
     3841 atctgaacag cgatttccag tccagccagt ttgcggataa cgccaatacg gtgaaagaga
     3901 gcgccgacgg cagtaccggc cgcattcccg gcttcatgct ctggggcgca cgcgtggcgt
     3961 atgactttgg cccgcagatg gcagatctga acctggcatt cggtgtgaaa aacatcttcg
     4021 accaggacta cttcatccgc tcttatgacg acaacaacaa aggcatctat gcaggccagc
     4081 cgcgcacgct gtatatgcag gggtcgttga agttctgatg tgttaacgcc cggcttgccg
     4141 ggcttttagc tggaatgtga ttatgttggc atttatccgt tttctttttg caggcctgct
     4201 gctggtgatc agccacgcct ttgccgccat ggttcaggac gaacacggca cgtttacact
     4261 cgaaaaaacg ccacaacgga ttgtggtgct ggaactctcg ttcgccgatg cgctggccgc
     4321 cgtggacgtc agcccgatcg gtattgccga cgataacgat gcaaaacgca tcctgcccga
     4381 agtgcgtgcg cacctgaaac cgtggcagtc cgtcggaacg cgcgcgcagc cgagcctgga
     4441 agccattgcc gctctgaaac cagacctgat cattgccgac agcagtcgcc atgcgggggt
     4501 ttacatcgcc ttgcagcaaa tcgcgccggt actgctgctt aagtcccgca acgaaaccta
     4561 cgctgaaaat ttgcaatctg cggctatcat cggcgaaatg gtgggtaaaa agcgagagat
     4621 gcaggcacgt ctggaacaac ataaagagag gatggcgcag tgggccagcc agcttcccaa
     4681 agggacacgc gtggcctttg gcacatcacg cgaacagcaa ttcaacctgc atactcagga
     4741 gacctggacc ggcagcgtgc tggcctctct ggggctgaac gttcccgctg cgatggcggg
     4801 ttcgtccatg ccgtccatcg gcctggagca actgctggcg gtcaatcctg cctggctgct
     4861 ggttgcccac tatcgcgaag agagcattgt taaacgctgg caacaagatc cgctctggca
     4921 gatgttaacc gccgcgcaga agcagcaggt tgcttcggtc gacagtaaca cctgggcgcg
     4981 gatgcgcggt atttttgctg cagagcgtat tgccgctgac acggtaaaaa tcttccacca
     5041 tcagccgctt accgttgtga aatgaccgcg ataaaacacc cgatgctgct gtgggggctt
     5101 cccgttgcag cacttattat tattttctgg ctgagtctgt tttgctactc ggccattcct
     5161 gtttccggag cagatgcaac ccgcgccctg ctgcctggac acacgccaac gctaccagaa
     5221 gcgctggtgc aaaaccttcg tttgccacga agcctggtcg ccgttctgat cggcgcaagc
     5281 ctggcgctcg cgggcacgct gctgcaaacc ctgacccaca acccaatggc ctctccttca
     5341 ctgctcggca ttaacagcgg cgcggcgctg gctatggcgc ttaccagcgc gctgagtccg
     5401 acgccgattg caggctattc tctgtcgttc atcgcggcat gcgggggcgg cgtgagctgg
     5461 ctgctggtca tgaccgcagg aggcggattt cgtcataccc atgacagaaa caaactgatc
     5521 ctcgcgggta tcgcgctgtc ggccttttgt atgggcctta cccgcatcac cctgctgctg
     5581 gccgaagatc atgcttacgg catcttttac tggctggcag gcggagtgtc ccacgcccgc
     5641 tggcaggatg tctggcagct cttgccggtg gtggtcactg cagtccctgt cgtgttactg
     5701 ctggcgaatc aactgaacct gctcaacctc agcgacagca ccgcccatac gctgggagtg
     5761 aacctgacga ggctacgttt ggtcatcaat atgttagtgc tgcttctggt tggtgcgtgc
     5821 gtcagcgtgg caggtccggt ggcgtttatc ggtctgctgg tgccacatct ggcgcgcttc
     5881 tgggcaggct tcgatcagcg caacgtactg ccagtgagca tgctgctggg ggccacgctg
     5941 atgttgctgg cagatgtact cgcacgcgcg ctggccttcc ccggagatct gcccgcaggc
     6001 gcagtgctgg cgctgattgg cagcccttgc tttgtctggc ttgtgaggag gcgaggatga
     6061 aaattgcgct ggttattttc atcacccttg ccctggcggg ctgtgcgctg ttatcactcc
     6121 atatgggagt gatccccgtg ccgtggcgcg cgctgctgac cgactggcag gccggacgcg
     6181 agcattatta tgtattgatg gagtaccgac tgccgcgctt gctgctggca ctgtttgtcg
     6241 gtgcagccct cgccgtggcg ggcgtgctga tacaggggat tgtgcgcaac cctctggcat
     6301 caccggatat tctcggcgtt aaccatgccg ccagcctggc ctctgtgggg gctctacttc
     6361 ttatgccgtc actgcccgtg atggtgctgc cgctgctggc ctttgcgggc ggcatggcgg
     6421 ggttgatatt actgaagatg ctggcaaaga cccaccagcc gatgaagctg gcgctcaccg
     6481 gcgtggcgct ttctgcatgc tgggccagcc tgacggatta tctgatgctc tcgcgcccgc
     6541 aggatgtgaa caacgccctg ctgtggctga ccggcagctt atggggccgt gactggagct
     6601 ttgtgaagat tgccatcccg ctgatgattt tatttctgcc gctgagcctg agtttttgcc
     6661 gcgatctcga cctccttgca ctcggcgatg cgcgcgccac cacgctcggt gtgtcggtgc
     6721 cccatacccg attctgggct ttgttactag ctgtcgccat gacatctacc ggcgtggccg
     6781 cctgcggccc gattagcttt attggtctcg tggtgccgca tatgatgcgt agcatcaccg
     6841 gtggacgtca ccgcagactg ctgcctgttt cagccctgac aggtgcgttg ctgttggtgg
     6901 ttgccgatct gctggcgaga attattcatc ccccactgga gctcccggtt ggcgtgctga
     6961 ccgccattat cggtgcgccg tggtttgtct ggttgcttgt gagaatgcga taaatgactt
     7021 tacgaactga aaatctgacg gtcagttacg ggacagacaa ggtacttaac gacgtttcac
     7081 tctcactgcc aacggggaag atcaccgccc tgatcggccc taacggttgc gggaaatcga
     7141 cgctgttaaa ctgtttttcg cggcttttaa tgccgcagtc tggcaccgta tttctcggcg
     7201 ataatcccat aaatatgctc tcatcacgcc agttggcccg caggctttcg ctgctgcctc
     7261 agcaccattt aacgccagag gggatcacag tccaggagct ggtttcgtat ggtcgtaatc
     7321 cctggctgtc actctggggg cgtctctccg ctgaagacaa tgcacgagtt aatgtcgcca
     7381 tgaaccagac ccggatcaat catcttgccg ttcgtcggtt aaccgagctt tccggcggtc
     7441 agcgccagcg cgcatttctg gcgatggtcc tggcccagaa tacgcccgtt gtattacttg
     7501 atgagccaac cacctatctt gatatcaatc accaggtgga cctgatgcgg ttgatgggcg
     7561 aactccggac tcaggggaaa acggtggtcg ctgtgctgca cgaccttaat caggctagcc
     7621 ggtactgcga tcaactggtg gtaatggcaa acggacatgt tatggcgcaa ggcacaccag
     7681 aagaggtgat gaccccagga ttgctgagaa cagtattcag cgtggaagcg gaaatacacc
     7741 ccgagccggt atctggcagg ccgatgtgcc taatgaggta gattgcacag gccgtaagaa
     7801 ccaaaccacg actgaatgaa actggactgg cgccagcaag cctgttcaga ctggggctga
     7861 acttttccgg actctgaaag attaccaata ctcatcgtcc atccgcttgc tttaggctga
     7921 caggttcata atcaacgcaa accagagctg tacaggcttg ggcgcggctt tcaaaccagt
     7981 cgtgatcacg gcaatcaatt ttgaactctg cttaacggac atttctgtat aacccttacg
     8041 gcaacgaaaa acgcgaagtt aaaattttag aaacccaaaa acgtgacatg actaagttta
     8101 gatttcaggg ggggagatca aaaaatttcg ctctgtgcca gagcggacat tcacggagct
     8161 ggttcattac caatgaggtt gggcttttga ggataaatca atgatcagac gccaacgtaa
     8221 atcaaaagca accctggaac ggaattgcta atccagtttc tgaccatcga tttttctaaa
     8281 aagtgtgcgt ttgctactac ttaggtaggt gcagctttct taatcaccgg cagccacgtt
     8341 atacaggcca gttgatggat cgattgttat caatgatatc ttcatgagtc ggtgtctcac
     8401 ccagcttacc gaagctggca taaagtgaag gcagacgggc ccgtccttct ccctttttcg
     8461 ccagagggaa agcgcgaagc atggtggcag cctcccagtc acaacaatag gatggtgtgc
     8521 acggctgctg acgccatgat tcagcgatag agccggaaaa tacggggtca aagccggtat
     8581 cattaaccag agtcatcgtg acctgtactg cggctggatg atctcctgct actgcaactg
     8641 ccaggcgacc gcggctccct tcaggtagtc tgttgtggtc aactaaaact ggcctccgcg
     8701 ttagagtttt tccagtatcg gttttctgat tcgtttggtg gtaacccacc attatattcg
     8761 tgcggtctta gtgcgctgta atatccaacg atatagtccg ttattgcgtg agctgcatcg
//
LOCUS       DACAOP010000144         8805 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.144, whole genome shotgun sequence.
ACCESSION   DACAOP010000144 DACAOP010000000
VERSION     DACAOP010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8805
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.144"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            307..8289
                     /locus_tag="IT892_004118"
                     /pseudo
     CDS             307..8289
                     /locus_tag="IT892_004118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010904796.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter adhesin-like protein
                     YeeJ"
     gene            complement(8551..>8805)
                     /locus_tag="IT892_004119"
     CDS             complement(8551..>8805)
                     /locus_tag="IT892_004119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HAP3137258.1"
                     /translation="LSLSPSIKRSAAIIKDAYIAITPDTSILHMASAYNTPVVAIYAD
                     YKTRWPAMADVSESVVVGKKFDNISLDEFAKALKSVLARI"
BASE COUNT         2497 a         2168 c         2164 g         1976 t
ORIGIN      
        1 aaaaattcgc ttcttagtgc aatgtcacta accttagttg aacattgttt tttaacggat
       61 agcggttttt taacatctta agcggcctcg acctttatgg ttgagggcgt tttgctatga
      121 atgccatcac cattttcccc tcgattataa aacttgagtt attcagtagt ctcccctctt
      181 gcaactcaca cccaaaactg cctaacgaaa agttattaat tttcaatcat attgctatca
      241 ggatttacat tttttcgctg tactagaaag ggcgcattta tgttagctca ttcagggaag
      301 gtaagcatgg ctacgaagaa gagaagtgga gaagaaataa atgaccgaca aatcttatgc
      361 gggatgggaa ttaaactacg ccgcttaact gcgggtatct gcctgataac tcaacttgcg
      421 ttccctatgg ctgcggcagc acaaggtgtg gtaaacgccg caacccaaca acccgttcct
      481 gcacaaattg ccattgcaaa tgccaatacg gtgccctaca cccttggagc gctggaatcg
      541 gcccaaagcg ttgccgaacg tttcggtatt tcggtggctg agttacgcaa actcaaccag
      601 tttcgtacgt ttgctcgagg ttttgataat gtccgccagg gtgatgaact ggatgtcccg
      661 gcacaagtta gtaaaaaaaa tttaaccccg ccgccgggta atagcagtga caacctcgag
      721 caacagatag ccagtacttc acagcaaatc gggtctctgc tcgccgaaga tatgaacagc
      781 gagcaagcag caaatatggc gcgtggatgg gcctcttctc agacttcagg cgcaatgaca
      841 gactggttaa gccgcttcgg taccgcaaga atcacgctgg gcgtggatga agattttagc
      901 ctgaagaact cccagttcga ttttctccat ccatggtatg aaacgcctga taatctcttt
      961 ttcagtcagc atactctcca ccgtactgac gagcgtacgc agattaacaa cggcttgggt
     1021 tggcgtcatt tcactcccac atggatgtcg ggcatcaact tctttttcga ccacgacctt
     1081 agccgttatc actcccgcgc cggcattggc gcggagtact ggcgcgacta tcttaaatta
     1141 agcagtaacg gctatttacg actgaccaac tggcgtagcg cacctgaact ggacagcgat
     1201 tatgaagcac gcccggccaa tggctgggat gtacgcgcag aaggctggtt acccgcctgg
     1261 ccgcaccttg gcggtaaact ggtctatgaa cagtattatg gcgatgaagt ggccctgttc
     1321 gataaagatg atcggcaaag taatcctcat gccataaccg ctggacttaa ctataccccc
     1381 ttcccgctga tgacctttag cgcggagcaa cgtcagggta aacagggcga aaatgacacc
     1441 cgttttgccg tcgattttac ctggcaacct ggcagcgcaa tgcagaaaca gcttgacccg
     1501 aatgaagtcg ctgcacgacg tagccttgca ggcagccgtt atgatctggt ggatcgcaac
     1561 aacaacatcg ttctggaata tcgcaaaaaa gaactggtcc gcctgaccct gacagacccc
     1621 gtgacaggga agtcaggaga agtgaaatca ctggtttcgt cgctacaaac caaatatgcc
     1681 ctgaaaggct ataacgtcga agccaccgct ctggaagctg ccggtggtaa agtggttaca
     1741 acgggtaaag atattctggt taccctgccg gcgtaccggt tcaccagtac gccagaaacc
     1801 gataacacct ggccgattga agtcaccgct gaagatgtca aaggcaattt ttcgaatcgt
     1861 gaacagagca tggtagtcgt tcaggcacct acgctaagcc agaaagattc ctcggtatcg
     1921 ttaagtaccc agacgttgag cgcggattcc cattcaaccg ccacactgac ttttattgcg
     1981 catgatgcag caggtaatcc tgttatcggg ctggtgctct cgacgcgtca cgaaggtgtt
     2041 caggacatca ccctttctga ctggaaagat aatggtgacg gaagctatac ccagatcctg
     2101 accacaggag cgatgtctgg cacgctgacg ctgatgccac agctgaacgg tgtggatgcg
     2161 gctaaagccc ccgccgtggt gaatatcatt tctgtttcgt catcccggac tcactcgtca
     2221 attaagattg ataaggaccg ttatctctcc gggaatccta tcgaggtgac ggtagaactg
     2281 agagatgaaa atgacaaacc tgttaaggag caaaaacagc aactgaatac cgcagtcagc
     2341 atcgacaacg tgaaacctgg tgtcactaca gactggaaag aaaccgcaga tggcgtctat
     2401 aaggcaacct ataccgccta taccaaaggc agtgggctta ctgcgaagct gttaatgcaa
     2461 aactggaatg aagatttgca taccgctgga tttatcatcg acgccaaccc gcagtcagcg
     2521 aaaattgcga cattatctgc cagcaataat ggtgtgctcg ccaatgagaa tgcagcaaac
     2581 accgtctcgg tcaatgtcgc tgatgaagga agcaacccaa tcaatgatca taccgtcacg
     2641 tttgcggtat taagcggatc ggcaacttcc tttaacaatc aaaacaccgc aaaaacggat
     2701 gttaatggtc tggcgactat tgatctgaaa agtagtaagc aggaagacaa cacggttgaa
     2761 gtcacccttg aaaatggcgt gaaacaaacg ttaatcgtca gttttgtcgg cgactcgagt
     2821 accgcacagg ttgatctgca gaagtcgaaa aatgaagtgg tcgctgacgg caatgacagc
     2881 gccacaatga ccgcgacagt tcgggatgca aaaggcaacc tgctcaatga cgtcaaggtc
     2941 accttcaatg ttaattcagc agcagcgaaa ctgagccaaa ccgaagtgaa tagccacgac
     3001 gggatcgcca cagctacgct gaccagtttg aaaaatggtg attatacggt tacggcctct
     3061 gtgagctctg gttctcaggc taatcaacag gtgattttta tcggtgatca aagtactgca
     3121 gccctgaccc tcagtgtgcc cccaggcgag atcaccgtca ccgacacagc gcctcaacag
     3181 ctgacggcaa ccttgcagga taaaaatggc aacccactaa aagataaaga aatcactttc
     3241 tctgtgccaa acgacgtcgc aagtcggttc tcgattagca acggcggaaa aggcatgacg
     3301 gatagtaacg gggttgcaat cgcctccctg accggcacgt tagcgggcac gcatatgatc
     3361 acggctcgtc tggctaacag caatgtcagc gatacacagc caatgacgtt tgtggcggat
     3421 aaagacagag cggttgtcgt tctgcaaaca tcgaaagcgg aaatcattgg gaatggcgtg
     3481 gatgagacaa ctctgacagc aacagtgaaa gatccttttg ataacgtggt taaaaatctg
     3541 tcagtagtct tccgcacctc ccccgcagac acgcaactga gtctgaacgc gcgtaatact
     3601 aatgagaacg gtattgctga agttaccctt aagggcacgg ttttgggggt ttacacagcc
     3661 gaagccacac tgcctaacgg caacagagat acgaagatag tcaatattgc gcccgatgcc
     3721 agcaacgcgc tggtcacgct gaacatcccg gctcaacagg tggtgacgaa taacagcgac
     3781 agcgtgcagc tgacggcgac ggtgaaagat ccgtcgaatc atccgctggc ggggataacg
     3841 gtaaacttca ccatgccaca ggacgtcgcg gcaaacttta cccttgaaaa taacggtatt
     3901 gccatcactc aggccaatgg cgaagcgcat gtcacgctca aaggtaaaaa agcgggcaca
     3961 catacggtaa ccgcaacgct gggtaacaat aatgccagcg atgcgcaacc agtcaccttc
     4021 gtggcggata aggacagcgc agttgtcgtt ctgcaaacat cgaaagcgga aatcattggg
     4081 aatggcgtgg atgagacgac tctgacggca acagtgaaag atccttttga taacgcagta
     4141 aaagatctac aggtcacctt cagtaccaac ccggcagata ctcaacttag tcagagcaaa
     4201 agcaatacta acgacagtgg tgtggctgaa gttaccctta agggcacggt tttgggtgtt
     4261 catacagtcg aagccacact gcttaacggc aatggctata cgacgacagt caatattgcg
     4321 cccgatgcca gcaacgcgca ggtcaccctg aacatccctg cttaacaggt ggtgacgaat
     4381 aacagtgaca gcgtgcagct tacggcgatg gtgaaagatc cgtcgaatca tccggtggcg
     4441 gggataacgg taaacttcac catgccacag gacgttgcgg caaactttac ccttgaaaat
     4501 aacggtattg ccatcactca ggccaatggg gaagcgcatg tcacgctgaa aggtaaaaaa
     4561 gcgggcacgc atacggttac cgcaacgctg ggtaataaca ataccagtga ttcgcagccg
     4621 gtaacatttg tggcggacaa aacctcggct caggttgtcc tgcagatgtc aaaagatgag
     4681 atcacaggta atggcgtcga taacgcaacg ctaactgcaa cggttaaaga tcagttcgac
     4741 aatgaggtga ataatcttcc ggtaacattc agctcagcct cttcaggact caccctgacc
     4801 ccgggagtaa gtaataccaa tgagtctggc atcgcgcagg ccactctcgc aggcgttgcc
     4861 tttggtgagc agacggtcac tgcatcactg gctaataatg gtgccagcga caacaaaact
     4921 gtgcatttta ttggcgacac agcggcggca aaaattatcg agttgacgcc tgtcccagac
     4981 agcataatcg ccggtacccc gcagaacagc tccggcagcg tcatcaccgc cacagtcgtt
     5041 gataataatg gctttccggt gaaaggtgtg actgtgaact tcaccagcaa cgcagcgaca
     5101 gccgaaatga cgaacggcgg tcaagccgtg acgaacgaac agggtaaggc taccgtcact
     5161 tataccaata cccgctcctc gatagaatca ggagcgagac cggataccgt tgaggccagt
     5221 ctggaaaatg gtagctccac gcttagcaca tcaattaatg tcaacgctga tgcgtctacg
     5281 gcacatctca ccttgctaca ggcacttttt gatacagtct ccgcaggcga cactaccaat
     5341 ctgtatattg aggtgaagga taattacggc aacggagtac cccagcagga ggtaaccctc
     5401 agagtatcac caagtgaagg cgtgaccctc agtaataacg gcataaatac taccaaccac
     5461 gacggctatt tatacgcaag ctttaccgct acaaaagccg gggtttatca agtgacggca
     5521 accctcgaaa atggcgattc gatgcaacaa acagtgacct atgtgccgaa cgtcgcgaat
     5581 gccgaaatca cgctggcagc ctcgaaggat ccggtgattg ccgacaataa cgatctcacg
     5641 acactaacag caacagtcgc tgatacagag ggcaatgcga tagccaacac tgaagtaaca
     5701 tttactctgc cggaagatgt gaaggcgaac ttcacgctga gcgatggcgg taaagcgatt
     5761 actgatgctg aaggcaaagc gaaagtcacg ctgaaaggta caaaagcagg cgctcatact
     5821 gttacagcat cgataactgg cggtaagagt gagcagttgg tggtgaactt tactgcggat
     5881 acgctcactg cgcaggttaa tcttaacgtt accgaggaca attttatcgc taataacgtc
     5941 gggatgacca ggctgcaggc aacagtgact gatggaaacg gcaacccgtt agccaatgag
     6001 gcggtgacat tcacgctacc ggcagatgtg agcgcaagct ttactctcgg acaaggcggt
     6061 tccgccatta ctgacatcaa cggcaaggct gaagttacac tgagcggtac aaaatccggc
     6121 acctaccccg tgacagttag cgtgaacaat tatggtgtca gtgatacgaa acaggtgact
     6181 ttgattgccg atgctggtac cgcaaaacta gcctccttaa cctctgtata ctcattcgtc
     6241 gtcagcacga ccgagggcgc gaccatgact gcaagcgtca ctgacgctaa cggcaacccg
     6301 gtagaaggta taaaagttaa tttccgcgga acttccgtca cgctaagcag caccagcgtt
     6361 gaaacggatg atcggggttt cgctgaaatt cttgtgacaa gcaccgaggt cggactgaaa
     6421 acagtttcag cctctctggc agataaacct actgaagtca tctcgcgatt actgaatgca
     6481 aaagcagata ttaattctgc aacgattacc agtctggaga tacctgaagg tcaggtcatg
     6541 gtcgcacaag acgtagcagt taaagctcac gtcaacgacc agtttggcaa tccgattctt
     6601 aatgaatctg taacattcag tgcagaacca ccagagcaca tgaccatcag ccaaaatatt
     6661 gtctctactg atacgcatgg tatagccgag gtcactatga cgcccgaaag aaacggttcg
     6721 tatatggtga aagcatccct ggcgaatgga tcctcttatg agaaggatct ggtggtaatc
     6781 gatcaaaaac tgacactctc ggcgtccagc ccgcttatcg gtgtcaattc cccaacaggt
     6841 gcaactctga cggcaacgct aacttctgca aatggcactc cagtggaggg tcaggtcatc
     6901 aactttagcg taacgccaga aggtgcgacg ttaagtggcg gaaaagtgag aaccaactct
     6961 tcaggtcagg ctccagtcgt tctgaccagc aataaagtcg gtacatatac ggtgactgca
     7021 tcgttccata acggcgtcac aatacagaca cagacaaccg tgaaggttac tggcaaccca
     7081 agcaccgcac atgttgctag ctttatcgct gatccgtcga ctatcgccgc caccaacagt
     7141 gatttaagta ccttaaaggc aacggttgag gatggcagtg gtaacctgat cgaaggtctc
     7201 actgtgtact tcgccttaaa aagcggctcc accacattaa cgtcattaac agcggtgaca
     7261 gatcaaaacg gaatcgcgac aacaagcgtg aaaggagcga taacggggag cgtcacggta
     7321 agcgcagtca cgaccgctgg tggaatgcaa acagtagata taacgctggt ggcaggcccg
     7381 gcagacgcct caaagtcagt ccttaagaac aatcggtcat cattgaaagg agactttacc
     7441 gatagtgctg agctacatct tgttctgcac gatatatcag gcaatccgat caaagtttct
     7501 gaagggctgg aatttgtgca gtcaggtacc aacgtgccct atgtgcaagt tagtgcaatt
     7561 gactacagta aaaatttctc aggcgagtac aaagccactg ttacaggcgg cggagagggt
     7621 atcgcaacgc tgatccctgt attgaatggt gttcatcaag ctggtctgag taccacaata
     7681 caattcactc gcgcagaaga caaaataatg agcggtacag tgtcagtcaa tggtactgac
     7741 ctaccgacaa ctacattccc ttcgcaggga ttcaccgggg cgtattatca gttgaataat
     7801 gacaactttg cccctggaaa aacggcggct gattatgagt tttcaagctc tgcctcctgg
     7861 gtcgatgttg atgctaccgg taaagtgaca tttaaaaatg tcggcagcaa ttgggaaagg
     7921 attacggcga cgccaaaatc aggaggccct agctatgtat acgaaatccg tgtgaagagt
     7981 tggtgggtga acgccggcga tgctttcatg atatacagcc ttgctgaaaa tttttgcagc
     8041 agcaatggct acacacttcc ccgtgcagat catttaaacc atagtcgttc ccgaggcatc
     8101 gggtcactgt acagtgaatg gggagatatg gggcattaca cgactgaagc tggttttcaa
     8161 tcaaatatgt attggtcatc tagtcccgca aactcaaacg aacaatacgt agtttccctg
     8221 gcaacaggtg atcaaagcgt atttgaaaag cttgggtttg cttatgcgac atgttataaa
     8281 aacctctgat tttccgttat aatttcttaa agagtgctcc attcggggca ctctttttta
     8341 cattccctct atagagcttg ctcttctctc accgaaaatg aataaataaa aatgcgatac
     8401 cgccagattc gcgttcggtg tgactatgat cgtatccggt gagtacagct ttgatccaaa
     8461 ggctggtttt ctgtgatgat tgaccagcct cagagtattg atgacaccac cgttcataac
     8521 agatcggcat tactttgcat acgtactgcc tcaaattctc gccaaaacac tttttaatgc
     8581 ctttgcgaat tcatccagac ttatattgtc aaattttttc ccaacgacga ctgactccga
     8641 aacatcggcc attgcgggcc atcgcgtttt gtaatcagca taaattgcaa caacgggggt
     8701 attataggca cttgccatat gtaatattga agtgtcagga gttattgcga tataagcatc
     8761 ttttatgatt gctgctgaac gtttaatcga tggtgacaag gataa
//
LOCUS       DACAOP010000145         8636 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.145, whole genome shotgun sequence.
ACCESSION   DACAOP010000145 DACAOP010000000
VERSION     DACAOP010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8636
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.145"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(362..1465)
                     /gene="asd"
                     /locus_tag="IT892_004120"
     CDS             complement(362..1465)
                     /gene="asd"
                     /locus_tag="IT892_004120"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAP3137259.1"
                     /translation="MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAA
                     PSFGGTTGTLQDAFDLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLR
                     MKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVAT
                     YQAASGGGARHMRELLTQMGHLYGHVADELATPSSAILDIERKVTTLTRSGELPVDNF
                     GVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQ
                     AFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAAVTGTLTTPVGRLRK
                     LNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA"
     gene            1658..2251
                     /gene="yhgN"
                     /locus_tag="IT892_004121"
     CDS             1658..2251
                     /gene="yhgN"
                     /locus_tag="IT892_004121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YhgN"
                     /protein_id="HAP3137260.1"
                     /translation="MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVREL
                     LIALLVMLVFLFAGEKILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAG
                     EEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
                     RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG"
     gene            complement(2308..3648)
                     /gene="gntU"
                     /locus_tag="IT892_004122"
     CDS             complement(2308..3648)
                     /gene="gntU"
                     /locus_tag="IT892_004122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HAP3137261.1"
                     /translation="MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSG
                     MPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRAH
                     YAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVP
                     GPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHL
                     GEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLV
                     AIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALT
                     GMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAG
                     GSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS"
     gene            complement(3652..4179)
                     /gene="gntK"
                     /locus_tag="IT892_004123"
     CDS             complement(3652..4179)
                     /gene="gntK"
                     /locus_tag="IT892_004123"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAP3137262.1"
                     /translation="MSTTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLHP
                     RRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKHYRDLLREGN
                     PNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLVVDIDQPL
                     EGVVASTIEVIKKGK"
     gene            complement(4318..5313)
                     /locus_tag="IT892_004124"
     CDS             complement(4318..5313)
                     /locus_tag="IT892_004124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GntR"
                     /protein_id="HAP3137263.1"
                     /translation="MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAAL
                     DELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYG
                     YKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSKSPCLDIAV
                     GFDNFEAARQMTTAIIARGHRHIAYLGARLDERTIIKQKGYEQAMLDAGLVPYSVMVE
                     QSSSYSSGIELIRQARREYPQLDGVFCTNDDLAVGAAFECQRLGLKVPDDMAIAGFHG
                     HDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGESVTPKMLDLGFTLSPGGSI"
     gene            complement(5537..6232)
                     /locus_tag="IT892_004125"
     CDS             complement(5537..6232)
                     /locus_tag="IT892_004125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HAP3137264.1"
                     /translation="MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVIN
                     DDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMGNKEQVPAGEFQIMSAGTGIRHS
                     EYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDM
                     ELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHAD
                     SDSEVLLFDLPPV"
     gene            complement(6354..7391)
                     /locus_tag="IT892_004126"
     CDS             complement(6354..7391)
                     /locus_tag="IT892_004126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP3137265.1"
                     /translation="MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQ
                     APIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTL
                     AQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
                     ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGD
                     LKAIVKTSHLVKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGV
                     LEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITHGAPNYVKESEVLTNLEILERGFE
                     QASPSTVTLAK"
     gene            7724..8212
                     /gene="yhhY"
                     /locus_tag="IT892_004127"
     CDS             7724..8212
                     /gene="yhhY"
                     /locus_tag="IT892_004127"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP3137266.1"
                     /translation="MSEIVIRHAETRDYEAIRQIHAQPEVYCNTLQVPHPSDHMWQER
                     LADRPGIKQLVACIDGDVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMRE
                     MIEMCDNWLRVDRIELTVFVDNAPAIKVYKKYGFEIEGTGKKYALRNGEYVDAYYMAR
                     VK"
     gene            8449..>8636
                     /locus_tag="IT892_004128"
     CDS             8449..>8636
                     /locus_tag="IT892_004128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HAP3137267.1"
                     /translation="MSNIVYLTVTGEQQGSISAGCGTSESTGNRWQSGHEDEIFTFSL
                     LNNINNTGLGSQFHGITF"
BASE COUNT         2195 a         2258 c         2107 g         2076 t
ORIGIN      
        1 gttttatgca ttcccagtac ggaaaaagga tccgcaaaat ggcctgcaat tagcgcgtta
       61 atcacgtctc tatcgatacg atcggacatg cttgtcttcc tgttttattg tgtcacccca
      121 tccaattgga tttttgactt ctggttgtga catttttttg acctgaacgg cgcagcactc
      181 tgtgcatcct ctctgcgtcg tcctcacttc aggtaaggct gtgaatactc atgtattcag
      241 ccacccttaa agaatagcca atgctctatt taactcccgg taaatcatga aacatctgcg
      301 cttactcctg tattacgcac taacaggggc ggcatcgcgc cccagattta atgaataaag
      361 attacgccag ttgacgaagc atccgacgca gcggctccgc ggccccccac agcagctggt
      421 cgcccacggt aaaggctgac aggaactctg gtcccatatt cagcttacgc aggcggccta
      481 ccggcgtggt cagcgtgccg gtaacggcag ctggggttag ctcacgcata gtgatttccc
      541 gatcgttcgg aacgactttc gcccacggat tgtgcgcagc cagcagttct tccacggtcg
      601 gaatagacac atcttttttc aatttaatag tgaatgcctg gctgtggcag cgcaatgccc
      661 cgacacgcac acataaacca tctaccggaa ttacggaaga tgtgttgagg atcttgttgg
      721 tttccgcctg ccctttccac tcttcgcggc tctgaccgtt atcgagctgt ttgtcgatcc
      781 acggaatcag gctacccgcc agcggcacgc caaagttatc caccggcagc tcaccgctac
      841 gggttaaggt tgtgactttg cgttcgatat cgagaatagc agaggacggg gtcgcgagtt
      901 catctgccac atggccatac agatggccca tctgggttaa taactcacgc atatgtcgcg
      961 caccaccgcc ggaagcggcc tggtaggttg caacggacac ccaatcaaca agatcattgg
     1021 cgaataaacc acccaacgac atcaacatca ggcttacggt acagttaccg ccaacaaaag
     1081 tcctgatgcc attatttaat ccgtcggtaa tgacgtcctg attgacgggg tcaagaatga
     1141 tgatggcgtc atctttcatg cgcagagacg atgctgcgtc aatccagtaa ccttgccatc
     1201 cgctttcacg aagctttgga tagatttcgt tggtataatc gccgccctga caggtcacaa
     1261 tgatatcgag ggcctttagc gcctccagat caaaggcatc ctgaagtgtg ccagtggttc
     1321 cgccaaaaga cggcgcagcc tggccaagct gagaagtaga aaagaagaca gggcgaatgg
     1381 cgtcgaagtc gcgctcttca accatgcgtt gcatgagaac ggagccgacc ataccgcgcc
     1441 agccgataaa accaacattt ttcataagcg tttttttcct gcaaagatgt gtgctgtata
     1501 aatgtgccgg tctcctcttg gcacatcttt caccatacaa aaagcagcca aagtcgcaag
     1561 tgaaattaat caatgatagc gaagccatca gtaatgcgac ttatcctgct ttgttagcac
     1621 gcagaaagtc cgcggcaatt atcagggaat ttgagttatg aatgaaatca tttctgcagc
     1681 agttttattg atcctgatta tggatccgct cggaaaccta cctattttca tgtccgtact
     1741 gaaacatact gaaccgaaaa gacggcgggc aatcatggtg cgagagttgc ttattgctct
     1801 cctggtgatg ctggtgttcc tgtttgcggg tgagaaaatt ctggcatttc ttagcctacg
     1861 agcagaaacc gtctccattt ctggcggcat cattctgttt ctgatcgcca ttaaaatgat
     1921 tttccccagc gcttcaggaa atagcagcgg gcttccggca ggtgaagagc catttatcgt
     1981 gccgttggca attccgttag tcgccgggcc gactattctc gccacgctga tgttgttgtc
     2041 tcatcagtac ccgaatcaga tggggcatct ggtgattgct ctgctgctgg cctggggcgg
     2101 cacctttgtc atcctgctac agtcttcgct atttttacgt ctgctgggcg agaaaggggt
     2161 gaacgcactt gaacgcctga tgggattgat tctggtgatg atggcaaccc agatgttcct
     2221 cgacggcatt cgaatgtgga tgaaggggta acgaggagag tttttcgaaa agaacccggt
     2281 agcgtcacaa ctaccgggcg aacaaactta actcaacagc tggaacgcaa tcatcccaac
     2341 gatggcaccg acagtgccga ggatggtttc catcatggtc caggttttca gcgtttcggc
     2401 ttcggtcgcg ccggtaaatt taccgaacaa ccagaaaccg gcgtcgttaa cgtggctgac
     2461 aacaatcgaa ccaccagcga tacaaatcga cagcgccgcc atttgcgcac cggagtagtt
     2521 cagttgttca ataaccggca tcaccagtcc taccgccgtt aaacaggcta cggtggcaga
     2581 accctgaatg atgcgcactg cagctgccag cacgaagcag gtgatagcaa tcggcaggcc
     2641 catgccggtt aacgcttcgc ccagtgccgg acctacgcca gagtcaacca gcacctgttt
     2701 gaacacgccg cccgcaccaa tcaccagcag aatgatcccc gccggttgca gcgcgtgacc
     2761 gcaaatctcc atcactttgt cttttggcat gccctgacgc attgccagac cgtaaatcgc
     2821 caccagacaa gcaaccagaa tcgcggtaaa cggatgaccg ataaactcaa accattcgta
     2881 agcagttgat ccttccggca caaaacgcgc ggcaatggtt ttcagcccta ccagcaccag
     2941 cggcagcagg atcagcgaca ggctgaatcc gaaagatggc attttgcctt cgccgagatg
     3001 cggttcgctg atgtcgtcag gaatatgcag ctcaacgtaa cggctgatga agttacccca
     3061 cagcggcccg gcaataatca ttcccggaat tgccgcacac aggccaatca ggatcatcca
     3121 gccaaagtcg gcattcatct gcgatgccag cagcatcggc gctggtccag gcaccagaaa
     3181 tgccgccgct gccgccacgc ctgcaaataa tgggattacc agcttcacca ggttcgtacc
     3241 ggtgtggcgc gccattgaga aagcaacgct aatcagcaga actatcgcca cttcaaagaa
     3301 cagcggtagc gcacagacca gccccgcaag gccgatggca taatgcgcgc ggctgtgacc
     3361 gaaggatttg agcattttga cggcaatctg atcgactgcg ccggtttcat gtaagatctt
     3421 gccaaacata gctcccaggg cgacaaccac cgccaggaag ccgagggtgc ctcccatccc
     3481 tttttccatc gtcgctgcga ttttatcgag cggcatacca gaaaaaaggc cagcccccat
     3541 ggacaccacc attaaagcca ggaaagcgtg catacgcgcc ttcatgacta aaaacagcag
     3601 cagtaaaaca gaccctactg ctgttaaaac aagcgttaat gtagtcacta cttatttgcc
     3661 ttttttaata acctcaatgg tgcttgccac aacaccttcc agcggttgat cgatatccac
     3721 caccagtaca tcggtttcgt ccgcacccgg ctcctgcagc gtttcaaact gcgtcaccaa
     3781 catttgggtt ttaaagaaat ggcctttgcg cgctttcagg cggctttcaa tcacatcaaa
     3841 atcgcctttc aaatagatga aagagagatt cggattacct tcacgcagca agtcgcgata
     3901 gtgttttttc aatgcagaac agacgatcag cgacacttta ttagtgcgct gcatagcaaa
     3961 cgcggcgtcg ttcagcgcct gcaaccacgg tttgcgatcg tcgtcattca gtggttcgcc
     4021 agacgccatt ttttcgatat tgcgccgtgg atggaggaaa tcgccatcaa gaaacgcggc
     4081 atgaagttga tgcgccactt cactggcgac cgcagatttg ccgctgcccg atacgcccat
     4141 caagacgtaa atgtggtgat catggttagt cgtgctcaaa gtggtgcccc cacaatacaa
     4201 gaattaaaaa tgttacgggt aactgttatc ggtaacattg tccagccgga caatatcaga
     4261 agcaatatcc atccatgcct taagtgtata agtgtgagct acttcaaatt tgtgggctta
     4321 aatagatccg cccggtgaca aggtgaaacc taaatctaac attttcggtg tcacagattc
     4381 gccacgaata cgcgccagca ggcgttcagc gccaatactg cccatccgct cacgcggcgt
     4441 cagcacgctc gcaagtcgtg gctccatcac ctgaccaatg tcatgaccgt ggaaaccggc
     4501 aatcgccata tcgtcaggaa cttttaaccc cagacgctga cattcaaacg ccgcgccgac
     4561 cgccaggtca tcattcgtac agaacacgcc atccagctgc ggatattccc gccgcgcctg
     4621 gcgaatcagt tcaataccgg aagagtaaga agaagattgc tcaaccatca cgctatatgg
     4681 caccaggcct gcatccagca tcgcctgttc gtatcccttc tgtttgatga tagtacgttc
     4741 gtcgagacgt gcgccgagat aggcaatgtg gcgatgcccg cgagcaataa tggcagtggt
     4801 catctggcgt gctgcttcaa agttatcaaa accgacggcg atatcaaggc atggcgactt
     4861 gctgtccatc agttccacca cgggaatacc cgccacttca atcatcttta aggtgcgcgg
     4921 cgtgtgggta cgttcggtga ggatcaggcc gtcgatattc caggagagca tggattcgag
     4981 gcgttcttgc tccatttccg gtttataacc gtagtgcgcc agcatggtct gataaccgtg
     5041 cgcgtcggtg acgctttcga ttccgcgtaa tacttccgcg aaaacctggt tggtgagaga
     5101 aggtaacagg acgccaatcg cccggctggt ggcgttagag aggatatcgg gcgcacgatt
     5161 gggaatatag cccagttcat caagagccgc ggcaatcttg ccgcgtagag cgacggaaac
     5221 ctgctccggg ttgcgtaaaa aacggctgac cgtcattttg gtcacgccta cacggtcagc
     5281 cacatcctga agtacgggtc ttttcttttt catcgtcctg aaggtacaaa agagatagat
     5341 tctcttagtt taacacggac acatcagaac cttcccgggg aaaacagtgc ttgtttacaa
     5401 ttattagata tacactaaat caattgcatc gcattgtgct aacgacgcgg caaaaccccg
     5461 gaagcgtaca tcagcacgcg accggagcga gcgaggaagc ctgcaaaaag gcaggcttca
     5521 aagatgccgt tgagttttaa accggcggca gatcgaacag taacacttcg ctgtcgctat
     5581 ccgcatggat ggagattgcc tgctcatccc agattgccag accatcgctg gtcgaggctt
     5641 tcacgccgtt aatggtgaca ttgcctttca ccacctggat ccagacgcgg cgttcagcgg
     5701 caatctgatg caccgactgc tcatctttca gcaacgccca gcggtacagt tccatatcct
     5761 gatgcacttt caatgaacca tctcgcgcat ccggcgagag caccagctgt ttgccctgta
     5821 cggcatcgaa gcgacgctgt tcataacgcg gcgtaatacc gttttcttca ggcatgatcc
     5881 agatctgata cagatgcaga cgctcggtgc tgcttgggtt gtactctgag tgacgaatac
     5941 ccgtaccagc actcataatc tggaactcac ccgccggaac ctgctcttta ttgcccatgc
     6001 tgtcctgatg ctcaacagta ccttccagca cgtaggtcaa aatttccata tctttatgcg
     6061 ggtgagtgcc gaagccctgc cctgcttcaa tcacgtcgtc gttaatcacg cgcagcgcgg
     6121 agaagcccat aaagttcgga tcgtaatagt tggcaaaaga gaaagtatgc caggagtcca
     6181 gccagccatg atttgcatga ccacgttcat ttgctttgcg taagtagatc atttgtattc
     6241 gccccctgaa tgatttcgat gggcttagtg tggacccgat ctgcctggga tgatagaggg
     6301 tgaaaattga ccctctgttc aaaaaaattg aactattcga ggggccatca aacttactta
     6361 gcgagagtta ctgtggaggg agaggcttgc tcaaatccgc gttcaaggat ttccagattg
     6421 gtaagaactt cagattcctt gacgtaattt ggcgcaccgt gggtgatggt ttgatacaac
     6481 gcatcataaa cgcgcccgta atcgcccatc tccggcttca tctcttctct gaccgtcacg
     6541 ccctcgtcat tgacatactc cagcacaccg accgaatcat ccgctgcgaa tcccggttcg
     6601 cccggcataa tattagcctt caggctggtt tcctgctggt cgataccgta tttaataaac
     6661 gaacctttct taccgtgaac gataaatttc ggataatcga ttttcaccag atggctggtt
     6721 ttgacgatgg ctttcaggtc gccataaaac agttgcgctt caaaggtgtc gtcaggattg
     6781 gctttattac gcaggctgcg gatgtcataa gcgacgtgat ccgggcgacc gaacagagaa
     6841 ataatctggt ccatcgtatg cacaccaagg ccataaaacg cgccatcctg cggcagccca
     6901 ggtttggttt ctgccaccgg gcggtaatag tcaaaatggc tttccacttc aacaatctct
     6961 cccaacttgc cactttcaat cgcttttttc gctgtcagga agcaggagtc aaagcgacga
     7021 ttctgatacg gcgtgacggt cagccctttg cttttcgcca acgcaaacag ctctttcgcc
     7081 tgcgcaagtg tcggagtgaa cggtttttcg accagcacat ttttcccggc ttccagcgcg
     7141 cgtttcgcgt actcgaaatg gctgtccgcg tgggtgcaga caacaaccag cttaacatcg
     7201 ggatcgttta gtacttcgtc gagatcgctg gtgaaatgga tatgggaata aatgggagcc
     7261 tgttcttccg gcttcgcatg gcgacgaaaa atatgcgcga catgccagct atccttgcgg
     7321 ttaagtacat acggcagatg gtaacgggtg gtgcttttgc cgaagccaat aaaggcgcag
     7381 ttgatgacca tgatttcgtc ctttttaagg tggttattta caccttagcg caaagcggac
     7441 gtggttccta ctggagtgcg cataacgaac acaagcactc ccgtggataa attgagaacg
     7501 aaagatcaaa aaaaaagcca gcacccggct ggctaagtaa tactggaagc aatgtgagca
     7561 atgtcgtgct ttcaggttct ccgcgagggt cttcctgatc gcgagacaat aataatcatt
     7621 ctcattcgca cttgtccaac actttttgca aaaaaatgca tttgactcgc atttgaaagt
     7681 caatgatgtt gaaagggaca tttaccccaa agaggacaaa ggaatgagtg agatagtaat
     7741 acgccacgca gaaacacggg attacgaggc catcaggcag attcacgccc agccggaggt
     7801 gtattgcaac acactacagg tgcctcatcc ttccgatcat atgtggcagg agcgactcgc
     7861 cgatcgtccc ggcatcaagc aactcgtcgc ctgtattgat ggagacgtcg tgggccatct
     7921 caccattgac gtgcaacagc gcccacgccg cagtcatgtt gccgattttg gtatctgtgt
     7981 cgactctcgt tggaagaacc gcggcgtcgc cagcgccctg atgcgagaga tgattgaaat
     8041 gtgcgacaac tggttgcggg tagatcgcat tgaactaacc gtgtttgtcg ataacgcccc
     8101 ggcaattaag gtctataaaa aatacggctt tgaaattgaa gggactggta agaagtacgc
     8161 attgcgtaat ggtgaatatg tcgatgcata ttatatggcg cgggtgaagt aagatagtgc
     8221 cctttttctg agatggaaaa agggtgtcat tcaaaatcga cataccttcc tttaaggtat
     8281 ttatttgccc aatacatata ttgagattta actcataatt acttcctaaa gtgtaatatt
     8341 ttatttttta atatatacgc ctacaatttc ctggagtaaa taaataacaa ttaacaagca
     8401 taatattgcc attgataaaa tagcatgcca taaaaggact tttcagggat gagtaatatt
     8461 gtttacctga cagtaacggg agaacaacaa ggaagcatct ccgcaggttg tgggacttct
     8521 gagtctacag gtaatcgttg gcagagcggg catgaggatg aaatatttac attctcactc
     8581 ttaaataata ttaataatac ggggcttggt tcacagttcc atggtataac attttg
//
LOCUS       DACAOP010000146         8482 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.146, whole genome shotgun sequence.
ACCESSION   DACAOP010000146 DACAOP010000000
VERSION     DACAOP010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8482
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.146"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(231..437)
                     /locus_tag="IT892_004129"
     CDS             complement(231..437)
                     /locus_tag="IT892_004129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfA family protein"
                     /protein_id="HAP3137268.1"
                     /translation="MELYREYPAWLIFLRRTYAVAAGVLALPFMLFWKDRARFYSYLH
                     RVWSKTSDKPVWMDQAEKATGDFY"
     gene            750..839
                     /gene="kdpF"
                     /locus_tag="IT892_004130"
     CDS             750..839
                     /gene="kdpF"
                     /locus_tag="IT892_004130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HAP3137269.1"
                     /translation="MSAGVITGVLLVFLLLGYLVYALINAEAF"
     gene            839..2512
                     /gene="kdpA"
                     /locus_tag="IT892_004131"
     CDS             839..2512
                     /gene="kdpA"
                     /locus_tag="IT892_004131"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HAP3137270.1"
                     /translation="MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVER
                     VLFRALGVSDREMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLA
                     LNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
                     STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGP
                     VASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGD
                     RRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGTDSSINMEGKESRFGVLVSSL
                     FAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVF
                     IAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGP
                     HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLV
                     SKKSQAASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS"
     gene            2535..4583
                     /gene="kdpB"
                     /locus_tag="IT892_004132"
     CDS             2535..4583
                     /gene="kdpB"
                     /locus_tag="IT892_004132"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HAP3137271.1"
                     /translation="MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSL
                     LTTCISIAMASGAMPGNALFSAAISGWLWITVLFANFAEALAEGRSKAQANSLKGVKK
                     TAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITG
                     ESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNE
                     IALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGV
                     AGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLA
                     DAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRM
                     IRKGSVDAIRRHVEANGGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVK
                     GGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQA
                     EGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGK
                     QMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMCLHSPDSAILSAVIFN
                     ALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
                     "
     gene            4592..5164
                     /gene="kdpC"
                     /locus_tag="IT892_004133"
     CDS             4592..5164
                     /gene="kdpC"
                     /locus_tag="IT892_004133"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HAP3137272.1"
                     /translation="MSGLRPALSTFIFLLLITGGVYPLLTTVLGQWWFPWQANGSLIR
                     EGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPELDKLIAARV
                     AALRAANPDASASVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIA
                     KYSQQPLVKYIGQPVVNIVELNLALDKLDE"
     gene            5157..7841
                     /gene="kdbD"
                     /locus_tag="IT892_004134"
     CDS             5157..7841
                     /gene="kdbD"
                     /locus_tag="IT892_004134"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     KdbD"
                     /protein_id="HAP3137273.1"
                     /translation="MNNEPLRPDPDRLLEQTAAPHRGKLKVFFGACAGVGKTWAMLAE
                     AQRLRAQGLDIVVGVVETHGRKDTAAMLEGLAVLPLKRQAYRGRHISEFDLDAALARR
                     PALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
                     QVRETVPDPFFDAADDVVLVDLPPDDLRQRLKEGKVYIAGQAERAIEHFFRKGNLIAL
                     RELALRRTADRVDEQMRAWRGHPGEEKVWHTRDAILLCIGHNTGSEKLVRAAARLASR
                     LGSVWHAVYVETPALHRLPEKKRRAILSALRLAQELGAETATLSDPAEEKAVVRYARE
                     HNLGKIILGRPASRRWWRRETFADRLARIAPDLDQVLVALDEPPARTINNAPDNRSFK
                     DKWRVQIQGCVVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVV
                     ATVINVVSFDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYR
                     EQRTRHLYEMSKALAVGRSPQDIAATSEQFIASTFHARSQVLLPDDNGKLQPLTHPQG
                     MTPWDDAIAQWSFDKGLPAGAGTDTLPGVPYQILPLKSGEKTYGLVVVEPGNLRQLMI
                     PEQQRLLETFTLLVANALERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVL
                     FGQAEILTLDLASEGSPHARQASEIRQHVLNTTRLVNNLLDMARIQSGGFNLKKEWLT
                     LEEVVGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAE
                     IGIDAHVEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIV
                     DVHGGTITAFNRPEGGACFRVTLPQQTAPELEEFHEDM"
     gene            7838..>8482
                     /gene="kdpE"
                     /locus_tag="IT892_004135"
     CDS             7838..>8482
                     /gene="kdpE"
                     /locus_tag="IT892_004135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator KdpE"
                     /protein_id="HAP3137274.1"
                     /translation="MTNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATR
                     KPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKP
                     FGIGELQARLRVALRRHSATTAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
                     AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFIT"
BASE COUNT         1792 a         2199 c         2455 g         2036 t
ORIGIN      
        1 gttttatcgg gttatttgtc tgctgacagg cgaaacccta cagatttata agaaagcctt
       61 aagtgagata tctgtcagat aagaacaatt aggaaaatat ttatatatat ttcatgaata
      121 tatgtttcga ttggtataac gatgtctaaa tattcctctg aacatcttcc tgatacaaaa
      181 aaccgccagc gtttccgctg gcggttttca atgtattcaa aactcagcaa tcaataaaaa
      241 tcaccagttg ccttttcggc ctgatccatc cacaccggtt tatcgctggt tttcgaccag
      301 acgcgatgca ggtagctgta aaagcgggcg cggtctttcc agaaaagcat gaaaggcagc
      361 gccagaacgc ccgctgcaac cgcataagta cggcgtaaaa agataagcca tgcaggatat
      421 tctctgtaga gttccatact tttctccccc ttttgtatct acccggtgaa tggcaccgga
      481 aaaatgaatt tgtttatctg atgaaaatag taccgccttt tgtgtaattt tactactcat
      541 ccgaccactt atttttgctt attgatggtt tatttacatt catcctgtaa ttaagttaca
      601 caaaagttaa attaatacta aacattagtt aaatcatggc ttttgccatt tttatacttt
      661 ttttacaccc cgcccgcaga tttttgcgaa atctttgcag ccagaattct acccttccgg
      721 tatcactttt aggccactgg aggtgcactg tgagtgcagg cgtgataacc ggcgtattgc
      781 tggtgttttt attactgggt tatctggttt atgccctgat caatgcggag gcgttctgat
      841 ggctgcgcaa gggttcttac tgatcgccac gtttttactg gtgttaatgg tgctggcgcg
      901 tcctttaggc agcgggctgg cgcggctgat taatgacatt cctcttcccg gtacaacggg
      961 cgttgagcgc gtactttttc gcgcacttgg cgtctctgac cgtgagatga actggaagca
     1021 atatctttgt gccattctcg gcctgaacat gctggggctg gcggtgctgt tttttatgtt
     1081 gctcggtcag cactatctgc cgcttaatcc acagcagttg ccagggctgt cgtgggatct
     1141 ggcgctgaat accgccgtca gctttgtcac caataccaac tggcaatctt atagcggtga
     1201 aaccacgttg agctatttca gccagatggc gggcttaacg gtgcaaaact ttctttctgc
     1261 cgccagcggg attgcggtga tttttgccct catccgtgcg tttacccgcc agagcatgag
     1321 cacgctcggg aatgcctggg tcgatctgct acgcatcacg ttatgggtgc tagtccctgt
     1381 ggcgttgttg attgcactgt tttttattca acaaggtgcg ctgcaaaact ttctgcctta
     1441 tcaggctgtg aataccgttg aaggagcgca acagctgtta cccatggggc ctgtagcttc
     1501 tcaggaagcg atcaagatgc tcggtactaa cggcggtggc ttctttaatg ccaactcgtc
     1561 gcatccgttt gaaaacccaa ccgcactgac caacttcgtg cagatgctgg cgatcttctt
     1621 gatcccaacg gcgctgtgct ttgcctttgg tgaagtgacg ggcgatcgcc gccaggggcg
     1681 catgttgctg tgggcgatgt cagtgatttt tgtcatctgc gtaggcgtgg tgatgtgggc
     1741 agaagttcag ggtaatcctc atctgctggc actgggcacg gacagcagca tcaatatgga
     1801 aggtaaagag agccgtttcg gcgtgctggt cagtagcctg tttgcggtcg tgacgacggc
     1861 ggcttcctgt ggcgcggtga ttgcgatgca tgattcgttt accgctctcg gtggcatggt
     1921 gccgatgtgg ctgatgcaaa ttggtgaagt ggtgttcggc ggtgtcggtt ctggtcttta
     1981 cggcatgatg ctgtttgtcc tgctggcggt gtttattgcc gggctgatga ttggtcgtac
     2041 accggaatat ctgggtaaaa aaatcgacgt acgcgagatg aaactgactg cactggcaat
     2101 tctggttacc ccgacgctgg tgctgatggg cgcggcgttg gcgatgatga ccgacgccgg
     2161 acgtagcgcc atgctcaacc ctggcccgca tggttttagc gaagtgctgt acgccgtgtc
     2221 atccgccgct aacaacaacg gcagcgcctt tgccggatta agcgccaact ctccgttctg
     2281 gaactgttta ctggcgttct gcatgtttgt cggtcgcttc ggggtgatta tcccggtgat
     2341 ggcaattgcc ggttcgctgg tgagtaaaaa gagccaagcc gccagctccg gcacgctgcc
     2401 aacgcacggc ccgctgtttg ttggcctgtt aatcggcacc gtgttgctgg ttggcgcact
     2461 gacctttatc cctgccctgg cgcttggtcc ggtggcggaa tatctctcct gatgatattg
     2521 agtgagcact gaatatgagt cgtaaacaac tggcgctatt cgaaccaaca cttgtcgttc
     2581 aggcgctgaa agaagcggtg aaaaaattaa acccgcaggc gcaatggcgc aatccggtga
     2641 tgtttatcgt ctggatcggc agtctgctga ccacctgtat tagcatcgcg atggcaagcg
     2701 gtgcgatgcc cggcaatgcg ctgtttagcg cggccattag cggttggctg tggatcaccg
     2761 tactgttcgc taatttcgcc gaggcgctgg cagaaggccg cagtaaagcg caggccaaca
     2821 gtctgaaagg ggtgaaaaaa actgcctttg cccgcaagct gcgtgagccg aaatatggcg
     2881 ctgcggcgga caaagttcct gccgaccaac ttcgtaaagg cgatatcgta ctggtagaag
     2941 ctggcgatat tatcccctgc gatggtgaag ttattgaagg gggtgcatcg gtcgatgaaa
     3001 gcgccatcac cggggaatcg gcaccggtga tccgtgaatc cggcggcgat tttgcctccg
     3061 tcaccggcgg cacgcgtatt ctttctgact ggctggtgat tgagtgtagc gttaaccccg
     3121 gcgagacatt tctggatcgg atgatcgcga tggtggaagg cgcacagcga cgcaaaacgc
     3181 cgaacgaaat tgccctgacc attctgctga ttgccctgac tatcgtcttt ttactggcaa
     3241 ccgccacgct gtggccgttt tccgcgtggg gcggtaatgc agtcagcgta acggtactgg
     3301 tggcgctgct ggtctgtctg atcccaacca ctattggcgg cctgttgtca gcgatcggcg
     3361 tcgccgggat gagccggatg ttaggcgcga atgtgattgc caccagcgga cgtgcagttg
     3421 aagcggcagg tgacgttgac gttctgctac tggataaaac cggcaccatc acactcggta
     3481 accgtcaggc gtcggagttt atccccgcgc agggcgtgga tgaaaaaacg ctggctgacg
     3541 ccgcacaact ggcttcgctg gctgatgaaa cgccggaagg ccgcagtatt gtgatcctcg
     3601 ccaagcagcg ttttaacctg cgcgagcgcg atgtgcagtc gctccatgcc acctttgtac
     3661 cgtttactgc gcaaagccgg atgagcggga tcaacatcga caaccgcatg atccgtaaag
     3721 gttctgtcga tgccattcgt cgccatgttg aggctaacgg tggtcacttc cctaccgatg
     3781 ttgatcaaaa agtcgatcag gttgcgcgtc agggagccac gccgctggtg gtggtggaag
     3841 gttctcgtgt gctgggcgtt attgcgctga aagatatcgt caaaggcggt attaaagagc
     3901 gcttcgccca gctgcgcaaa atgggcatta aaacggtgat gattaccggc gataaccgtc
     3961 tgactgccgc cgcgattgct gcggaagcgg gtgtcgatga ttttctcgcc gaagcgacac
     4021 cggaggccaa gctggcattg atccgtcagt atcaggcgga aggtcgtttg gtagcgatga
     4081 ccggcgacgg caccaacgat gctccggcgc tggcgcaggc agatgtcgcg gtggcgatga
     4141 actccggcac ccaggcggcg aaagaggcgg gcaatatggt cgatctcgac tctaacccga
     4201 ccaagttgat cgaggtggtg cacattggca aacagatgct gatgacccgt ggctcgctga
     4261 ccaccttcag cattgccaac gatgtggcga aatacttcgc cattattccg gcggcattcg
     4321 cggcaacgta tccgcagtta aatgcgctga acatcatgtg cctgcattcg cccgactccg
     4381 caatcctcag tgcggtgatt ttcaacgcct tgattatcgt ctttttgatt cccctggcgt
     4441 taaaaggcgt gagttataaa ccgcttaccg cttctgccat gttgcgccgt aacttatgga
     4501 tttacggtct gggtgggctg ctggtgccgt ttatcggtat caaagtcatt gatttactgc
     4561 tgaccgtttg cggtctggtg tgaggtttac catgagtgga ttacgtccgg cattatcaac
     4621 atttatcttt ctgttattga ttactggcgg cgtttacccg ctgctgacca ccgtactggg
     4681 gcaatggtgg tttccctggc aggccaatgg ttcgttgatt cgtgaaggtg atacggtgcg
     4741 cggttcggca ttaatcgggc agaattttac cggcaacggc tattttcatg gtcgcccgtc
     4801 ggcaacggca gaaatgccct ataatccaca ggcttctggc gggagcaatc tggcggtcag
     4861 taaccctgag ctggataaac taatagccgc acgcgttgct gcattacggg ccgctaaccc
     4921 ggatgccagc gcgagcgttc cggttgaact ggtgacggca tcggcaagcg ggctggacaa
     4981 taatatcacc ccgcaagcgg cggcctggca aatcccacgc gtggcgaaag cgcgtaatct
     5041 cagcgttgaa cagctcacgc aactgatcgc aaaatacagc caacaaccgc tggtgaaata
     5101 tatcggccag ccggttgtca acattgttga actcaatctg gcgctggata aacttgatga
     5161 ataacgaacc cttacgtccc gaccccgatc gtctgctgga acaaactgcc gcgccgcatc
     5221 gggggaagct gaaagttttc ttcggtgcct gtgcaggcgt cgggaagacc tgggcgatgc
     5281 tggcagaagc ccagcgactg cgggcgcaag ggctggatat tgtggttggc gtggtagaaa
     5341 cccacgggcg aaaagatacc gccgccatgc tggaagggct ggctgttctg ccgttaaaac
     5401 gccaggcgta ccgtgggcgg catatcagcg agtttgatct cgatgccgcc ctcgcccgcc
     5461 gcccggcgct gatcttaatg gacgaactgg cgcacagtaa tgcgccaggt tcccgtcatc
     5521 ccaaacgctg gcaggatatc gaagaactgc tggaagctgg cattgatgtt ttcactaccg
     5581 tcaacgttca gcatctggaa agtctgaatg atgtggtcag cggcgtcacc ggaattcagg
     5641 tacgggaaac cgtgcccgat ccttttttcg atgccgccga cgacgtggtg ctggtggact
     5701 tgcccccgga cgatctgcgc cagcggctga aagaaggcaa agtctatatt gccgggcagg
     5761 cggagcgcgc cattgaacat tttttccgca aaggtaatct gatcgccctg cgcgaactgg
     5821 cactgcgccg tactgccgat cgcgttgatg agcaaatgcg cgcctggcgg gggcatcctg
     5881 gcgaagagaa agtgtggcac acgcgcgacg cgatcctttt atgcatcggc cataacaccg
     5941 gcagcgaaaa actggtccgc gcagcggcgc ggctggcgtc acggctgggt agcgtctggc
     6001 acgcggtgta tgttgaaacc cctgccctgc accgcttacc ggaaaaaaaa cgtcgggcaa
     6061 ttctcagcgc cttacgtctg gcgcaggaac tgggcgcgga gacggcaaca ctttctgatc
     6121 cagcggaaga gaaagcggta gtgcgttatg cccgtgaaca taatctcggc aagattattc
     6181 tcggtcgccc ggcctcgcgc cgctggtggc gtcgggaaac gtttgctgac cgactggcgc
     6241 gcatcgcccc cgatctcgat caggtgctgg tcgcgcttga tgaaccaccc gcccgcacga
     6301 ttaacaacgc gccggataac cgctctttta aagacaagtg gcgtgtacaa attcagggat
     6361 gcgtggttgc cgccgcgtta tgcgccgtta tcaccttaat tgccatgcag tggctgatgg
     6421 cgtttgatgc cgccaacctg gtgatgctgt atctgcttgg cgtggtggtg gtggcgctat
     6481 tttatggacg ctggccttca gtggttgcca ccgtcattaa tgtagtgagt ttcgatctct
     6541 tttttatcgc cccacgcggc acgctcgccg tctctgatgt gcaatatctg ctgaccttcg
     6601 cggtgatgtt aaccgtcggg ctggtgatcg ggaaccttac tgctggcgtg cgttatcagg
     6661 cgcgggtagc ccgttaccgc gagcaacgca cacggcactt atatgaaatg tcgaaagctc
     6721 tggcggtggg ccgcagtccg caggatatcg ctgccaccag cgaacaattt attgcctcca
     6781 cgtttcatgc ccgcagtcag gtgttgttgc ccgatgacaa cggtaaattg cagccgttaa
     6841 cacatccgca aggaatgacg ccgtgggacg atgccatcgc gcagtggagt tttgataaag
     6901 gcctgcctgc gggcgcgggc accgacacgt tacccggtgt accgtaccag attttgccgc
     6961 taaaaagcgg cgagaaaacc tacgggctgg tggtggtgga gccggggaat ctgcgccagt
     7021 tgatgatccc ggaacagcag cgcctgctgg agacgtttac gctgttagtc gccaatgccc
     7081 ttgagcggct gacgctaacc gccagcgaag aacaggcgcg gatggcaagc gaacgtgaac
     7141 agatccgcaa cgccctgctg gcggcgcttt cgcatgattt acgcacgccg cttacggtgc
     7201 tgtttggtca ggcagaaatc ttaacgctcg atctggcaag cgaaggatca ccccacgccc
     7261 gccaggccag cgagatccgt cagcatgtgc tgaacactac ccgactggtg aataatctac
     7321 tggatatggc gcgaattcag tccggcggct ttaatttgaa gaaagagtgg ttaacgctgg
     7381 aagaagtagt cggcagcgcg ctgcaaatgc tggaaccggg tttatcgtcg cccatcaatc
     7441 tttctctgcc agaaccgctg accttaatcc acgttgacgg gccactcttt gaacgggtgc
     7501 tgattaatct gctggagaac gcggtgaaat atgcgggtgc gcaggccgaa attggtatcg
     7561 atgcccacgt tgagggcgaa aatctacaac tggatgtctg ggataacggc cccggtcttc
     7621 cgccaggcca ggagcagacg atatttgata agtttgctcg cgggaataaa gagtcggcag
     7681 taccgggggt agggcttgga ctggcaattt gtcgggcgat agtggatgta cacgggggca
     7741 ctattaccgc gttcaaccga ccggaaggtg gtgcctgttt tcgtgttaca cttccccagc
     7801 aaactgcccc tgaacttgaa gaatttcatg aggatatgtg acaaacgttc tgattgttga
     7861 agatgaacag gctattcgtc gctttctgcg cacggcgctg gagggcgacg ggatgcgcgt
     7921 ctttgaggcc gaaacgctgc aacgcggctt gctggaagcg gcaacccgta agccagattt
     7981 gattattctc gatctcggcc tgcccgatgg tgatgggatt gagtttatcc gcgacctgcg
     8041 ccagtggagc gcggtgccgg tgattgtgct ttccgcacgc agcgaagaga gcgacaaaat
     8101 cgccgcgctg gatgccggag cggatgatta tctgagtaag ccgtttggca ttggcgaatt
     8161 gcaggcccgt ctgcgcgtcg cattacgccg ccactctgcc accaccgcgc ccgatccgct
     8221 ggtaaaattt tccgatgtta ccgtcgattt agccgcccgc gtgattcacc ggggtgagga
     8281 agaggtgcat ctcacaccaa ttgagttccg cctgctggcg gtgctgctca acaatgccgg
     8341 aaaagtactc acccagcgcc agctccttaa ccaggtgtgg gggccaaacg cggtcgaaca
     8401 cagtcactat ttgcgtattt atatgggaca tctgcgacaa aaactggaac aggatcccgc
     8461 ccgcccacgc catttcatta ct
//
LOCUS       DACAOP010000147         8357 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.147, whole genome shotgun sequence.
ACCESSION   DACAOP010000147 DACAOP010000000
VERSION     DACAOP010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8357
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.147"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(244..3360)
                     /locus_tag="IT892_004136"
     CDS             complement(244..3360)
                     /locus_tag="IT892_004136"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HAP3137275.1"
                     /translation="MTHQTHTIAESNNFIVLDKYIKAEPTGDSYQSESDLERELIQDL
                     RNQGYEFISVKSQSAMLANVREQLQNLNGVVFNDSEWRRFTEQYLDNPSDGILDKTRK
                     IHIDYICDFIFDDERLENIYLIDKKNLMRNKVQIIQQFEQTGSHANRYDVTILVNGLP
                     LVQIELKKRGVAIREAFNQIHRYSKESFNSENSLFKYLQLFVISNGTDTRYFANTTKR
                     DKNSFDFTMNWAKSDNTLIKDLKDFTATFFQKHTLLNVLVNYSVFDSSQTLLVMRPYQ
                     IAATERILWKINSSYKAKNWSTPESGGFIWHTTGSGKTLTSFKAARLATELDFIDKVF
                     FVVDRKDLDYQTMKEYQRFSPDSVNGSENTAGLKRNLDKDDNKIIVTTIQKLNNLMKA
                     ESDLPVYNQQVVFIFDECHRSQFGEAQKNLKKKFKRYYQFGFTGTPIFPENALGSETT
                     ASVFGRELHSYVITDAIRDEKVLKFKVDYNDVRPQFKSLETETDEKKLSAAENQQAFL
                     HPMRIQEITQYILNNFRQKTHRTFPGSKGFNAMLAVSSVDAAKAYYATFKRLQEEAAN
                     KSATYKPLRIATIFSFAANEEQNAIGEISDETFDTSAMDSSAKEFLDAAIREYNSHFK
                     TNFSTDSNGFQNYYRDLAQRVKNQDIDLLIVVGMFLTGFDAPTLNTLFVDKNLRFHGL
                     MQAFSRTNRIYDATKTFGNIVTFRDLERSTIDAITLFGDKNTKNVVLEKSYAEYMEGF
                     TDAATGEAKRGFMAVVAELEQRFPDPASIESEKEKKDFVKLFGEYLRTENILQNYDEF
                     ATLKALQQIDLSDPVAVEKFKAEHYVDDEKLAELQTIRLPADRKIQDYRSAYNDIRDW
                     QRREKEAEKKEKSTTDWDDVVFEVDLLKSQEINLDYILGLIFEHNRQNKGKGEMIEEV
                     KRLIRSSLGNRAKEGLVVDFIQQTNLDDLPDKASIIDAFFTFAQHEQLREAEALIKEE
                     NLNEEAAKRYIRTSLKREYATENGTELNETLPKLSPLNPQYKTKKQAVFQKIVSFIEK
                     FKGVGGKI"
     gene            complement(3482..4765)
                     /locus_tag="IT892_004137"
     CDS             complement(3482..4765)
                     /locus_tag="IT892_004137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAP3137276.1"
                     /translation="MSELSYLEKLLDGVEVEWKTLEDISIKISSGGTPKTGVSEFYDG
                     DIPWLRTQEVNFCDIWDTEVKITESGVKNSSAKWIPKNCVIVAMYGATVGKIGINKIP
                     MTTNQACANIQLNEEVAHYRYVFHFLCSQYTYIKSLGTGSQTNINAQIVKNIKIPIPC
                     PDNPEKSLAIQSEIVRILDKFTALTAELTAELTAELNMRKKQHNYYRDQLLTFKEGEV
                     EWKALGEIGEFIRGKRFTKADYVEDGGISVIHYGEIYTRYGVYTTHSLSQVRADMAAS
                     LRYAKHGDVVITDVGETVEDVGKAVAWLGDDDIAIHDHCYAFRHSLNPKFISYYMQTD
                     SFISEKAKYVARTKVNTLLINGFSKIMIPVPYPKDHEKSLKEQARIVEILDKFDTLTN
                     SITEGLPREIELRQKQYEYYRDLLFSFPKPETVSN"
     gene            complement(4762..6318)
                     /locus_tag="IT892_004138"
     CDS             complement(4762..6318)
                     /locus_tag="IT892_004138"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAP3137277.1"
                     /translation="MTSIQQRAELHRQIWQIANDVRGSVDGWDFKQYVLGALFYRFIS
                     ENFSSYIEAGDDSICYAKLDDSVITDDIKDDAIKTKGYFIYPSQLFCNVAAKANTNDR
                     LNADLNSIFVAIESSAYGYPSEADIKGLFADFDTTSNRLGNTVKDKNARLAAVLKGVE
                     GLKLGDFNEHQIDLFGDAYEFLISNYAANAGKSGGEFFTPQHVSRLIAQLAMHGQTSV
                     NKIYDPAAGSGSLLLQAKKQFDNHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFD
                     IKLGNTLTEPHFRDEKPFDAIVSNPPYSVKWIGSDDPTLINDERFAPAGVLAPKSKAD
                     FAFVLHALNYLSAKGRAAIVCFPGIFYRGGAEQKIRQYLVDNNYVETVISLAPNLFFG
                     TTIAVNILVLSKHKTDTKVQFIDASELFKKETNNNILTDAHIEQIMQVFASKEDVAHL
                     AKSVAFETVVANDYNLSVSCYVEAKDNREIINIAELNAELKTTVSKIDQLRKDIDAIV
                     AEIEGCEVQK"
     gene            6501..6722
                     /locus_tag="IT892_004139"
     CDS             6501..6722
                     /locus_tag="IT892_004139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001603498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP3137278.1"
                     /translation="MQSINFRTARGNLSEVLNNVEAGEEVEITRRGREPAVIVSKATF
                     EAYKKAALDAEFASLFDTLDSTNKELVNR"
     gene            6722..7102
                     /locus_tag="IT892_004140"
     CDS             6722..7102
                     /locus_tag="IT892_004140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP3137279.1"
                     /translation="MRHISPEELIALHDANINRYGGLPGMSDPGRAEAIIGRVQARVA
                     YEEITDLFEVSATYLVATARGHIFNDANKRTALNSALLFLRRNGVQVFDSPELADLTV
                     GAATGEISVSSVADTLRRLYGSAE"
     gene            7107..7286
                     /locus_tag="IT892_004141"
     CDS             7107..7286
                     /locus_tag="IT892_004141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PdcA protein"
                     /protein_id="HAP3137280.1"
                     /translation="MARKYNKLSREALKMLLDGVSRREVKQYLAGKQIGARTAIAVLC
                     RQEMVVLKQRMPGSR"
     gene            7314..7673
                     /locus_tag="IT892_004142"
     CDS             7314..7673
                     /locus_tag="IT892_004142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pdcB"
                     /protein_id="HAP3137281.1"
                     /translation="MKAVITPFVQKELGVATFKVDQEVRKLVEAGRKFIMEPVPRELI
                     EHMDDGLVVSEQTMATNEALQPFFNSDELFRRIGGIDSLVAWLRRKEGQVRLGHVVLA
                     GQQAYHESTGNGMGNPW"
     gene            7597..8010
                     /locus_tag="IT892_004143"
                     /pseudo
     CDS             7597..8010
                     /locus_tag="IT892_004143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611482.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
     gene            complement(7960..8277)
                     /locus_tag="IT892_004144"
     CDS             complement(7960..8277)
                     /locus_tag="IT892_004144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I deoxyribonuclease HsdR"
                     /protein_id="HAP3137282.1"
                     /translation="MPERENYQQVTLQARLVSALETLNPNVPSDTLIEVAKIVATPQT
                     PVLIKNNKLFHQYLIEGVPVEYSVMEQEQWVTKHTHVRLIDFVLWSTKTGHRVRVFPV
                     SVF"
BASE COUNT         2175 a         1853 c         1904 g         2425 t
ORIGIN      
        1 ggagggacag ctgatagaaa cagaagccac tggagcacct caaaaacacc atcatacact
       61 aaatcagtaa gttggcagca tcaccggcat tcaaaatcat tatggccgcg atctatttct
      121 ggctgttctc tatcactttt ggcggcatcg tcgctcatgg gtaaggggag tatattagcc
      181 atttggaacc ccacggtctc ttgcgggttt aattaagaac ccgcaagaaa aacacgaatt
      241 gggctatatt tttccgccta cgcctttaaa cttctcaata aacgagacga ttttctggaa
      301 aactgcctgt tttttcgttt tatattgcgg gtttaacgga ctaagttttg gtaatgtctc
      361 gtttaattct gtgccatttt cggtggcgta ttcgcgtttt aaagacgtgc gaatatagcg
      421 tttcgccgcc tcttcattga gattttcttc tttaatcaac gcttctgctt cacgtagctg
      481 ttcgtgttga gcaaaggtaa agaacgcgtc aatgatgctg gctttgtctg gtaaatcatc
      541 caggttcgtt tgctgaataa aatcgaccac caggccctct ttcgcccggt tccccaggct
      601 tgaacgaatt aagcgtttga cctcttcgat catttcgccc ttgcctttat tttgtctgtt
      661 atgttcgaaa atcagtccaa ggatataatc caggtttatt tcctgagact tcagcaaatc
      721 gacctcaaaa accacgtcat cccagtcagt ggttgatttc tcttttttct cagcttcttt
      781 ctcacggcgc tgccagtcgc gaatatcgtt ataggcagaa cgataatcct gaatcttgcg
      841 atcagcaggg agacgaattg tttgcaattc agcgagcttt tcatcatcca cataatgttc
      901 tgctttgaat ttttctactg caacaggatc gctaagatcg atttgttgca gggctttcag
      961 cgtggcaaat tcatcatagt tttgcaggat gttctcggta cgcaggtatt caccaaacag
     1021 ttttacgaag tctttcttct ctttttcact ttcaatactg gcagggtcag ggaaccgttg
     1081 ttccagttct gcaactactg ccataaagcc gcgcttagct tcaccagtag cagcatcagt
     1141 aaagccttcc atatactctg cataactctt ttctaacact acatttttgg tgtttttgtc
     1201 accaaacagc gttatggcat caatagttga gcgttccaga tcccggaaag tgacgatatt
     1261 accgaaggtt ttagtggcgt cataaatgcg gttggtgcgg gaaaatgcct gcatcaggcc
     1321 gtgaaaacgt aagtttttat cgacgaatag cgtgttcaat gttggagcat cgaagccggt
     1381 taagaacatc cccacgacaa ttagcagatc gatatcctga tttttaaccc gctgggctaa
     1441 atcacgatag tagttctgaa aaccgttact gtcggtgcta aagttagttt taaaatggct
     1501 gttatattca cgaattgcag cgtccagaaa ctctttagca ctgctgtcca ttgcgctggt
     1561 atcaaaagtt tcatcggaaa tctcaccaat ggcattttgt tcttcattgg cggcaaagga
     1621 gaagattgtc gcaatacgca gcggtttata ggtagccgat ttattagcgg cttcttcttg
     1681 taaccgttta aacgtcgcat aataggcttt cgcggcatcc acgctgctca ctgccaacat
     1741 agcattaaaa ccttttgagc cagggaaggt acggtgagtt ttctggcgga aattattcag
     1801 aatatattgc gtaatttcct gtatacgcat gggatgaaga aacgcctgct gattttcagc
     1861 cgcactcagt tttttctcgt cggtttctgt ctctaaagac ttaaactgtg gccgcacatc
     1921 gttgtagtcc accttgaatt taagcacttt ttcatctcga atcgcatcgg taataacata
     1981 tgaatgcaat tcacgaccaa atacgctggc ggttgtttct gagcctaagg cgttttccgg
     2041 gaaaataggg gtaccggtaa aaccaaactg ataatagcgt ttgaatttct tcttcaggtt
     2101 tttctgtgct tctccaaact ggctgcggtg gcattcatca aatataaaca ccacttgctg
     2161 attgtataca ggcaggtcgc tttctgcttt catcaggtta ttgagtttct gaatagtggt
     2221 gacgataatt ttgttatcat ccttatccag atttcgttta agacctgcgg tattttccga
     2281 tccattgaca ctgtctggcg aaaaacgctg atattccttc atggtctggt aatcgaggtc
     2341 tttcctgtcg accacaaaga agactttatc aataaagtcc agttctgttg ccagacgcgc
     2401 ggctttaaag ctggtcaggg ttttaccaga accggtagtg tgccagataa agccaccact
     2461 ttcgggggta gaccagtttt tcgctttata ggagctgttg attttccata agatacgctc
     2521 agtggcggca atctggtacg gtcgcatcac cagtagcgtc tggctactgt caaaaacgct
     2581 gtagttcacc agaacattca gcagagtatg tttctggaaa aaggtagcgg taaagtcttt
     2641 gaggtcttta atcagcgtgt tgtctgattt tgcccaattc atggtgaagt caaaactgtt
     2701 tttatcgcgc tttgtcgtgt tggcaaaata acgggtatcg gtgccgttag aaatgacaaa
     2761 cagttgcaga tacttaaaca gggaattttc gctgttaaaa ctctctttac tgtaacgatg
     2821 tatctggttg aaagcctcac gaatcgccac cccgcgtttt tttagttcga tttgcaccag
     2881 cggtaaacca ttaaccagga tcgtgacgtc ataacggtta gcatgagaac ccgtctgttc
     2941 aaactgctgg ataatctgca ccttattgcg catgagattc tttttatcta tcaaatagat
     3001 gttctcaaga cgctcgtcat caaaaataaa gtcgcaaata tagtcgatat ggattttacg
     3061 ggtcttatcc agaatgccat cgctcgggtt atccagatac tgctccgtga aacgccgcca
     3121 ctcgctgtca ttaaacacca caccattgag gttctgaagc tgttcccgaa cattggccag
     3181 catcgccgac tgtgatttta cggatataaa ttcatagccc tgattccgca ggtcctgaat
     3241 cagttctcgt tccaggtccg attcgctctg gtagctgtcg cctgttggct cagctttgat
     3301 gtacttatca aggacgataa agttattgga ttcagcaatg gtgtgtgtct gatgagtcat
     3361 agcgcatcct ttgtgccgtc tggcaagggc cggaagggag ttaagggtga cttccggcac
     3421 gtaaaaaata gtctatatac agaccggatg ttaaggtggc ccggtcggta gcaacggtca
     3481 attaattact gacagtttca ggttttggga aactgaacag taaatcacgg tagtattcgt
     3541 attgtttctg gcgcaactcg atttcacgcg gaagaccttc ggtgatggag ttagtcagtg
     3601 tgtcgaattt gtcgagtatt tcgacaatgc gagcttgttc cttaagtgat ttttcgtgat
     3661 ctttaggata tggaaccgga atcataattt ttgaaaaacc attaatgagt agtgtattaa
     3721 cttttgttct ggctacatac tttgcttttt cagaaataaa cgaatcggtt tgcatgtaat
     3781 aggaaataaa ttttggattc aaagaatgtc gaaaagcata acagtgatca tgaatagcga
     3841 tatcgtcatc cccaagccat gccactgctt taccaacgtc ttctacagtc tcccccacgt
     3901 cagttatcac gacatctcca tgtttggcat agcgtaatga cgctgccata tcagctctaa
     3961 cctgtgataa cgaatgagtt gtgtaaacac catatcgtgt atatatctca ccataatgga
     4021 ttacactgat accaccatct tctacataat ctgctttagt aaaacgtttt ccacgaataa
     4081 actcaccaat ttcccccaaa gctttccact caacctcacc ttctttaaaa gtcagcaatt
     4141 ggtcgcgata gtagttgtgc tgttttttac gcatgttaag ctcagcggta agctcagcgg
     4201 taagctcagc ggtaagtgca gtaaacttat ccagaatccg aacgatttca gactggatgg
     4261 caagggactt ttccggatta tccgggcagg ggatggggat cttaatattt ttgacaatct
     4321 gcgcatttat gtttgtctgg gaccctgttc caagggattt gatatatgtg tattggctac
     4381 acaagaagtg aaatacatat ctataatgag caacttcttc attaagttga atatttgcgc
     4441 acgcttgatt tgttgtcatt ggaattttgt ttatgccgat tttccccaca gttgccccat
     4501 acatagcaac aatgacacaa ttctttggta tccattttgc actagagttt ttaactccag
     4561 actcagttat ttttacctcg gtatcccata tatcacaaaa gtttacttct tgagttctca
     4621 accaaggaat gtcgccatca taaaattctg atacgccagt tttaggggtt cctccagatg
     4681 atatctttat agaaatatcc tcaagggttt tccactcaac ctcaacccca tccagcaatt
     4741 tttccagata actcaactcg ctcatttctg cacctcgcag ccttcaattt cagccacaat
     4801 cgcatcaata tctttacgca actggtcgat tttgctgacc gtagttttaa gctctgcatt
     4861 tagctcagca atattgataa tttcgcggtt atctttcgct tctacatagc agctcaccga
     4921 caggttatag tcattagcga caacggtctc aaacgcgaca gatttcgcca gatgagcaac
     4981 atcttccttg ctggcaaata cctgcataat ctgttcgata tgggcatcgg tcaggatatt
     5041 gttgttggtc tcttttttga atagttcgct ggcatcaata aactgaactt tggtatccgt
     5101 tttatgttta gacaacacca gaatattgac ggcaatggtg gtgccaaaga acaggttcgg
     5161 tgcgagtgaa atcacggttt cgacatagtt attgtcaacc agatactgac ggattttctg
     5221 ctccgcgccg ccacggtaaa aaatgcccgg gaagcagaca atcgcagcac gacctttggc
     5281 agaaagatag ttcagcgcat gtaatacaaa cgcaaagtca gctttggatt tgggggccag
     5341 aacgccagcc ggggcaaaac gttcatcgtt aatcagcgtc gggtcatcgc tgccaatcca
     5401 tttcaccgaa tacggcgggt tagaaacgat ggcatcaaac ggtttttcat ctctgaagtg
     5461 cggttcagtc agcgtattgc ccagcttgat atcaaacttg tcgtagttga tgttgtgcaa
     5521 aaacatgttc atacgcgcca ggttataggt cgtatggttg atttcctgac caaaaaaacc
     5581 ttcttcgatg atatggttat caaactgttt tttcgcctgc aacaacagtg agccggaacc
     5641 cgctgccggg tcgtagattt tgttaacgct ggtctgcccg tgcatagcca gttgtgcaat
     5701 cagcctggag acgtgctgcg gtgtaaagaa ctcaccgcct gacttaccgg catttgccgc
     5761 atagttagaa atcaggaact cataggcatc accgaacagg tcaatctgat gttcgttgaa
     5821 gtcaccaagt tttaaccctt caaccccttt cagaaccgca gccaggcggg catttttatc
     5881 tttaacggtg ttacccaggc ggttactggt ggtatcgaaa tcagcaaaca aacctttgat
     5941 gtcagcttct gaaggataac cgtaagcaga actttcgata gcaacgaaga tgctgtttaa
     6001 atctgcattc aatctgtcat tggtatttgc tttcgcagct acgttgcaga aaagctggct
     6061 tgggtagatg aagtagcctt tggttttgat ggcatcgtct ttaatgtcat cagtaattac
     6121 gctgtcatcc agtttcgcat aacagatact gtcatcaccg gcttcaatat aactggaaaa
     6181 attttcgctg ataaaacggt agaaaagtgc gcccagaacg tattgcttaa aatcccatcc
     6241 atcgaccgaa cccctgacat cgttagcaat ttgccagatt tgacgatgaa gctctgcacg
     6301 ttgttgaata cttgtcattt tcatccactt atttcaggct tatgtaattg gcggtgattc
     6361 tacagcaact tggatgcttt agcagttcgg acattaggct acgaatgacc tgcctagagg
     6421 tttgttaagc cgcaaagtgc tggtgcttta tgcctgtgaa gtttataatt gtgtacacat
     6481 aacgagtaca cgaggtgttt atgcaatcca ttaacttccg taccgcgcgc ggcaaccttt
     6541 ctgaagtgct caacaatgtt gaggccgggg aagaggttga aatcacccgc agaggccgtg
     6601 agccagcagt aattgtcagc aaggctactt tcgaagccta caaaaaagcg gcgctggatg
     6661 ctgaatttgc atccctgttt gacaccctgg actccaccaa caaggaactg gttaaccgat
     6721 aatgaggcat atatcaccgg aagaacttat tgcgcttcat gatgcgaata taaaccgcta
     6781 cggcggcctg ccgggaatgt ctgatccggg cagggcagag gccattatcg ggagagttca
     6841 ggccagagtt gcctacgaag agatcaccga ccttttcgaa gtctccgcca cctacctagt
     6901 ggctacagcg agagggcata tattcaatga tgccaataag cgtaccgcgc taaacagtgc
     6961 gctgttattt ctacgccgta acggggtgca ggtatttgat tcacctgaac tggcagacct
     7021 taccgtaggg gctgcgaccg gagagatatc tgtatcttct gtcgccgaca cgttacgtag
     7081 attgtatggt tctgcggagt agattaatgg cacgcaaata caacaaattg tcccgtgaag
     7141 cgttaaagat gcttcttgat ggcgtgagtc gccgcgaggt aaagcaatac ctggctggta
     7201 agcaaattgg tgccaggacc gctattgctg tgttatgccg tcaggaaatg gttgtgctta
     7261 aacagagaat gccgggcagc agataaagcc caatcagtga tgaaaggtgt gatgtgaaag
     7321 ccgtaattac tccctttgta caaaaagagc ttggcgtcgc cacattcaaa gtggatcagg
     7381 aagtcagaaa gctggtggag gctggccgta aatttattat ggagccggtg ccgcgtgagt
     7441 taatcgagca catggacgac ggcctcgttg tttccgagca aactatggca acaaatgagg
     7501 cgttgcagcc gttttttaac agcgatgaac tgtttcgccg tattggtgga attgactcgc
     7561 tggtagcgtg gttgcgcagg aaagaggggc aggtcaggct gggccatgtc gttctcgccg
     7621 gacagcaggc ttaccatgaa agcactggaa atggcatggg aaacccgtgg taagcccgtc
     7681 ggggtgatgt tccacagcga tcaaggcagt cattatacga gcaggcagtt ccggcagtta
     7741 ctgtggcgat accggatcag gcagagtatg agtcggcgtg gaaactgctg ggataacagc
     7801 ccaatggagc gcttcttcag gagtctgaag aacgaatggg tgccagcgac gggctatgta
     7861 agtttcagcg atgcagctca cgccataacg gactatatcg ttggatatta cagcgcacta
     7921 agaccgcacg aatataatgg tgggttacca ccaaacgaat cagaaaaccg atactggaaa
     7981 aactctaacg cggtggccag ttttagttga ccacaacaca aaatcaatta atcgaacatg
     8041 agtatgcttg gtcacccatt gttcttgctc cattaccgag tattcaacag gcacaccttc
     8101 gattaaatat tggtgaaaga gtttgttgtt tttaatcagt acaggcgttt gcggtgtggc
     8161 aacgattttc gctacttcga ttaaggtgtc actgggcaca tttgggttta aggtttccaa
     8221 ggcagagact aaacgcgcct gtagcgtgac ttgctgatag ttttcacgtt caggcatatc
     8281 accatctggt gcgatgtcat agccattttg gtattggtaa cctagctctt taaaccaatc
     8341 gaggcattgt tgttcta
//
LOCUS       DACAOP010000148         8253 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.148, whole genome shotgun sequence.
ACCESSION   DACAOP010000148 DACAOP010000000
VERSION     DACAOP010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8253
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.148"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(379..454)
                     /locus_tag="IT892_004145"
     tRNA            complement(379..454)
                     /locus_tag="IT892_004145"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(419..421),aa:Asn,seq:gtt)
     gene            complement(555..2197)
                     /gene="yeeO"
                     /locus_tag="IT892_004146"
                     /pseudo
     CDS             complement(555..2197)
                     /gene="yeeO"
                     /locus_tag="IT892_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416491.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxic metabolite efflux MATE transporter YeeO"
     gene            2202..2277
                     /locus_tag="IT892_004147"
     tRNA            2202..2277
                     /locus_tag="IT892_004147"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2235..2237,aa:Asn,seq:gtt)
     gene            complement(2315..3265)
                     /gene="cbl"
                     /locus_tag="IT892_004148"
     CDS             complement(2315..3265)
                     /gene="cbl"
                     /locus_tag="IT892_004148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator Cbl"
                     /protein_id="HAP3137283.1"
                     /translation="MNFQQLKIIREAARQDYNLTEVANMLFTSQSGVSRHIRELEDEL
                     GIEIFVRRGKRLLGMTEPGKALLVIAERILNEASNVRRLADLFTNDTSGVLTIATTHT
                     QARYSLPEVIKAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIASERLSNDPQLVA
                     FPWFRWHHSLLVPLDHPLTQITPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLPA
                     DIVLSAQDSDVIKTYVALGLGIGLVAEQSSGEQEEENLIRLDTRHLFDTNTVWLGLKR
                     GQLQRNYVWRFLELCNAGLSVEDIKHQVMENSEEEIDYQI"
     gene            complement(3367..4284)
                     /gene="nac"
                     /locus_tag="IT892_004149"
     CDS             complement(3367..4284)
                     /gene="nac"
                     /locus_tag="IT892_004149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen assimilation transcriptional regulator"
                     /protein_id="HAP3137284.1"
                     /translation="MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELN
                     QQLLIRTKRGVTPTDAGKILYTHARAILRQCEQAQLAVHNVGQSLSGQVSIGFAPGTA
                     ASSITMPLLQAVRAEFPEVVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQA
                     LLKEDLFLVGTQDCPGQSVDVNAIAQMNLFLPSDYSAVRLRVDEAFSLRRLTAKVIGE
                     IESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANL
                     SPQAQAVKELLMSVMSSPVMEKRQWQLVS"
     gene            4610..4685
                     /locus_tag="IT892_004150"
     tRNA            4610..4685
                     /locus_tag="IT892_004150"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4643..4645,aa:Asn,seq:gtt)
     gene            complement(4741..5676)
                     /gene="ldtA"
                     /locus_tag="IT892_004151"
     CDS             complement(4741..5676)
                     /gene="ldtA"
                     /locus_tag="IT892_004151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HAP3137285.1"
                     /translation="MMRRVNILCSFALLFASQNSLAVTYPLPPEGSRLVGQSLTVTVP
                     DHNTQPLETFAAQYGQGLSNMLEANPGADVFLPKPGSQLTIPQQLILPATVRKGIVVN
                     VAEMRLYYYPPDSNTVEVFPIGIGQAGRETPRNWVTTVERKQEAPTWTPTPNTRREYA
                     KRGESLPAFVPAGPDNPMGLYAIYIGRLYAIHGTNANFGIGLRVSQGCIRLRNDDIKY
                     LFDNVPVGTRVQIIDQPVKYTTEPDGSKWLEVHEPLSRNRAEYESDRKVPLPVTPSLR
                     AFINGQEVDVNRANAALERRSGMPVQISSGSRQMF"
     gene            complement(5738..6817)
                     /gene="cobT"
                     /locus_tag="IT892_004152"
     CDS             complement(5738..6817)
                     /gene="cobT"
                     /locus_tag="IT892_004152"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HAP3137286.1"
                     /translation="MQTLADLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALAI
                     QLAGMPGLNGIPHVGKKTVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVL
                     AAQAGANVHVVDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYT
                     RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVV
                     RRAITLNQPNPQDGVDVLAKVGGFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAAC
                     QMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMDMRLGEGSGAALAMSIIEAACA
                     IYNNMGELAASNIVLPGNTTSDLNS"
     gene            complement(6829..7572)
                     /gene="cobS"
                     /locus_tag="IT892_004153"
     CDS             complement(6829..7572)
                     /gene="cobS"
                     /locus_tag="IT892_004153"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HAP3137287.1"
                     /translation="MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLL
                     GAISGLVFMVLQAWCGAPLAALFSVLVLALMTGGFHLDGLADTCDGVFSARSRDRMLE
                     IMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRH
                     RYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQL
                     LKRTLGGQTGDTLGAAIELGELVFLLALL"
     gene            complement(7569..8114)
                     /gene="cobU"
                     /locus_tag="IT892_004154"
     CDS             complement(7569..8114)
                     /gene="cobU"
                     /locus_tag="IT892_004154"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HAP3137288.1"
                     /translation="MMILVTGGARSGKSRHAEVLIGDSSQVLYIATSQILDDEMAARI
                     EHHRQSRPEHWRTVERWQHLDELIHADINPNEAVLLECVTTMVTNLLFDYGGDKDPDE
                     WDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
                     QLAAAANEVWLVVSGIGVKIK"
BASE COUNT         2283 a         2228 c         1776 g         1966 t
ORIGIN      
        1 ctcgtcatat tgcttataaa aaatccccgt tcccagagaa ataatattta ttaaaatggc
       61 aggtcttctt tttctgatta ccgaagacaa agtggcaatt acgtatagtt tcccgataaa
      121 gacgcgacag ctacatcccg cataaggcat ttttctcttt atctttgtac ggtacttcat
      181 ggaacagaat ttttgacctt gtgaatcgtg atgtctgttg gggaggggca atttgctcac
      241 tgaagcgtga gactcgatta agcgcacgaa acacagaaat caaaaaaccc ggccactttt
      301 ttacaaagtg gccgggtaaa aataattttt attttttaac tgtcctgagt ctcatagaga
      361 tgtctcaaaa ctaaaatttg gctcctctga ctggactcga accagtgaca tacggattaa
      421 cagtccgccg ttctaccgac tgaactacag aggaatcgtg agaacgaggc gaatattagc
      481 gatgcccacc cacaatgtca aagcctgttt tttaaatttg aaatcgtttg ctgaaataat
      541 ctgcattttg tcgtttattc cgacacagct ggcttttttt cacacttttg cggttcgggt
      601 cgagggtatt tccacagcca acgtccagta accattcgcc agtaaaacag cacggcccgc
      661 acagcccagt cggcaaacat tcccatccag acaccaacca ccccccagcc aagcatgatg
      721 cccagcacat aaccgacgac aacccggcaa ccccacatgc tcaacataga aacccacatg
      781 gcgtaacggg catcacgagc ccccttaaat ccagcgggta gcacccatga ggcggaccaa
      841 ataggcataa ataaagcatt tagccaaatc agaatcacaa cgacatgttt aacctgtgga
      901 tcctgggtgt aaaacgatgc cataaccccg gcaaagggag ccgttagcca ggcgatggcc
      961 gttaatccaa gagtggaaag ccagaacaca tgccgcaact gaatctctgc ttgcgctatc
     1021 tgccctaccc caaccttcgg cctgtaatga tcgtagaagc agagccgagc gcacttccgg
     1081 gtaagttgat aagagccgca attgaaaacg cgataaaatt tccggcaata acactggtcc
     1141 ccatcccggc aacgaacatt tgggttaata accgaccact ggtaaataac actgattcga
     1201 cactcgctgg aataccaatc cccatgactt cccagataat gctaaaattc agcggtttaa
     1261 aatagctctt taacgaaatc cttagcgcag gattaaaacc aatcgccagc acccacaaaa
     1321 ttgcaactgc gccaatataa cgagaaatgg ttaaacccaa cccagccccg acaaatccca
     1381 gtcccggcca ggagaaaagg ccgtaaatca atatgccgct aataataata ttaagaatat
     1441 tcaggctacc gttaatcagt agcggtattt tcgtattccc tgcaccacga agtgccccgc
     1501 taccaattag agtgatggca gctgctggat aactgagtac cgtcagctcc agataagtca
     1561 acgccagtgc tttaacttct gtcgtggcat cacccgcgac gaaatcaata atttgctcgc
     1621 caaaatgatg aataagcgtt gccaacagta cggcaaacaa cgtcatgatc accaatgact
     1681 gccgcgtcgc caccctcgct cgtcgtcgat cccgcttacc gagactaaat gccacaacga
     1741 cagtagtacc aagatcgata gcagcaaaaa aagccataat gaccatattg aagctgtccg
     1801 ccaatcccac gccggccatc gcatcttttc ccagccagct gaccagaaaa gtgctcagaa
     1861 cccccatcaa caggacacag gcattctcca tgaagatagg aacagcaagc ggggttatct
     1921 cgcgccagaa caacactttg tagctcttgc gtttagcgtg ccagcgagtg ccgtgaacaa
     1981 cctgacgtaa agcagaggag atattcaaag ccgaccttaa ttgcagaaag tgaaaccaca
     2041 tttcaaataa tgagggagaa tcagcaaagc tgcaaagatt ttcgccaaca aattgtctgc
     2101 aaatgcaaca aactgttgat agaaacggca aacagttggg gaatttaaaa atcgggtttg
     2161 acaaaagatt tttcgccgtt aagatgtgcc tcaacagcga ttcctctgta gttcagtcgg
     2221 tagaacggcg gactgttaat ccgtatgtca ctggttcgag tccagtcaga ggagccaaat
     2281 ttctgaaaag cccgctttta tagcgggctt tttgctatat ctgataatca atttcctctt
     2341 cactgttttc catcacctgg tgcttgatat cctcaactga cagtcctgca ttacaaagtt
     2401 ccagaaagcg ccagacatag ttacgctgaa gttgtcctcg cttcagtccc aaccagacag
     2461 tattagtatc gaaaagatgc cgcgtatcca ggcggattaa attctcttcc tcttgttcgc
     2521 cgctggattg ttcggcaact aatccgatcc caagcccaag agcaacatag gttttaatga
     2581 catcagaatc ctgtgcactt aatacaatat ctgccggcaa acctttgcgg gcaaatgcgt
     2641 catcaatgcg tgagcgcccc gtaatcccct gtcggtaagt aattaacggc cacttcgcta
     2701 ttgattccag cgtcaacggt gtaatttgcg tcaagggatg atcgagtgga acaagcaaac
     2761 tatggtgcca acgaaaccac gggaaggcga cgagctgcgg gtcattactc aaacgctcgc
     2821 tggcgatacc aatatcagct tcgccatttt gcaacaacgt cgcaatttcc tgtggcgtac
     2881 cctggattag ctccagccga acctccggga aaagttcgcg aaaagcttta atgacctcag
     2941 gcaagctata acgtgcctga gtatgcgttg ttgcaatagt gagaacgcca gacgtatcgt
     3001 tggtaaacag gtctgcaagc cgacgaacat tactggcttc attaagaata cgttctgcaa
     3061 tgaccagtaa tgctttgccc ggttcagtca tgcccagcag tcgcttacct cgtcgaacaa
     3121 atatttcgat gccaagttca tcctccagtt cccgaatatg acggctgacg ccggactgtg
     3181 aggtaaaaag catattcgca acctctgtca ggttgtaatc ctgacgtgca gcctcgcgga
     3241 ttatctttag ttgttggaaa ttcacggtaa actccgggca gttcagattt tccgttattg
     3301 ttaaagtcta atgcccggca taacaaataa taaaaacccg catcttattc catcccgata
     3361 taacgcttag ctcaccaatt gccactgcct tttttccatc actggagaac tcatcactga
     3421 cattaacaac tctttcactg cctgtgcctg tggtgacaag tttgctctgg cgggtaaatt
     3481 taaggacaaa gagagactca ttgaaggagt ggtaatgcgt gacatccacc catttactgc
     3541 gccacataac gaacgcgcag ccgattcagg taatactgca acgcccatgc cgctggcaat
     3601 cgctgcggta agcgtggcaa tagactcaat ttcaccaatg acttttgccg tgagtcgccg
     3661 tagggaaaaa gcctcatcaa cacgaagtct aacagcactg taatcactgg gaagaaagag
     3721 gttcatttgc gcaatagcat taacatcaac gctttgcccc ggacaatctt gagtccctac
     3781 caggaaaaga tcttctttca gtaaagcctg actggataca ccagccacag gggaatgctc
     3841 ataaatcacc gccatatcga gttggtgatt tatcagtttt tcgttaagca ctgcaccact
     3901 attttcatga agatagataa cgacctccgg gaattcagcg cgaaccgcct gtaataaggg
     3961 catggtgatg gatgacgcag cggttcctgg cgcaaagcca atcgagactt gccccgataa
     4021 tgactgacca acgttatgca ccgccagttg ggcctgctca cactgacgta aaatggcccg
     4081 cgcatgggta tagagaattt ttccggcgtc tgttggcgta acgccccgtt ttgtgcgaat
     4141 caaaagttgt tgatttaact caccttccag tgtggcaacc tgctggctga gcgctggttg
     4201 tgcgatatgc aatacttcag cagcctgagt caggctacca atatctacaa tttttacgaa
     4261 gtatttcagg cgtctgaagt tcatgttgcc tccggttttt gagaatcggc ccaagtgccg
     4321 ccattactta caaccagact gcaagatgct tgccagtttt attttggcgt tgatgtacaa
     4381 gctaaccaac tgtcaaataa gagattatga tagattcgtc attggctctt ttcaccagca
     4441 gtcgcgttcc cctgccctat aaaaggaggg tatgcaccac gatggttcat taccaataag
     4501 attgaaatct catcactttg ttgaaattga cagcaaacaa acaaaaaaat gcatttcacc
     4561 ctttgacatc accatgcact gccattaata tgcgccccgt tcacacgatt cctctgtagt
     4621 tcagtcggta gaacggcgga ctgttaatcc gtatgtcact ggttcgagtc cagtcagagg
     4681 agccaaattc aaaaaagcct gctttctagc aggctttttg ctttctaatt accagcgctc
     4741 ttaaaacatc tgtcttgaac cagaactaat ttgcacaggc attcccgatc gacgttccaa
     4801 cgcagcattt gcgcgattca catcaacttc ttgcccgttg ataaacgccc gcaaagatgg
     4861 ggttaccggc aatggcactt ttcggtcaga ctcatattct gcacgattgc gcgacagcgg
     4921 ctcatgaact tccagccact ttgaaccatc cggttccgtt gtgtatttca ctggctgatc
     4981 aataatttgt acacgagtgc ctacaggaac attatcaaac agatatttga tatcgtcatt
     5041 acgcagacga atacagccct gacttacacg gagcccaata ccaaaattgg cattggtacc
     5101 gtggatggca tacaacctgc caatataaat cgcgtacagc cccatggggt tatcgggccc
     5161 cgcaggaaca aatgcgggca aactctcccc tcgtttcgca tattcgcgcc gggtgttcgg
     5221 cgttggcgtc caggttggtg cttcttgttt acgttcaacg gtagtcaccc agttacgcgg
     5281 ggtttctcgc ccagcctggc cgataccaat aggaaagact tccactgtat tactgtctgg
     5341 cggatagtaa taaagacgca tttcagcgac gttaaccaca atccctttac gaacagtggc
     5401 gggcaaaatc agttgctgcg gaatggtgag ttgtgagcca ggcttcggca aaaaaacatc
     5461 agcgcccgga ttcgcttcca gcatattact taacccttgc ccgtattgtg cggcaaaagt
     5521 ctccagcggc tgagtattgt gatcaggaac agttacagta agcgactgcc ccaccaaacg
     5581 gctaccctct ggaggtaacg gataagttac cgccaggcta ttttggctgg caaaaagcag
     5641 agcaaatgag caaagaatat ttacacgacg catcatgtcc ctttcctaag tcgcgaatac
     5701 tatccgataa gtatagcttt tatcagactt ttcgttttta gctgttcaaa tcagaagtcg
     5761 tattccccgg tagaacaata ttactggcag caagttcgcc catgttgttg tatatcgcac
     5821 aagcagcttc gatgatggac atcgccagag ctgcaccact cccctcacct aaacgcatat
     5881 ccatattgag ataaggctcc agccccaaat gcgagagcgc tatacgcgcg cctttttctg
     5941 ccgacaagtg agaagggatg agatacggtt tgattgcagg agacatctgg caggctgcga
     6001 gcgcagcagc ataagaaaga aatccatcca gcaacacggg taaaccgcag gaagcagcac
     6061 ctaacatcac tccagctatt ccgaccaaat caaatccacc cacttttgcc aggacatcaa
     6121 caccatcctg aggatttggt tgattcaacg taatcgcccg acgcacaaca tcaattttat
     6181 tagccagttt atctgtcggc aggtttgcgc caatcccaac cacttcttca ggatcccggc
     6241 cagtgattgt gctgactatt gccgctgccg gtgtcgtgtt tgccatcccc agttcaccta
     6301 caccaaacag cgtgacacca ttttttgcca gctcccgcgt ataacatatg acgtccaaaa
     6361 gcaacttttc agcctgacgg cgactcattg ccggagctga agcaatattg ccgctacctc
     6421 gtgcgacacg catgttgata agcccgggga taggctcagc agtatcaata ccaacatcaa
     6481 ctacgtggac gttagcgccc gcttgtgctg ccagcacaca cacgccggtt gttccacggg
     6541 tcatattttc agcctgtatg gctgtcactt cttttggaga aatagcgacc ccttcctccc
     6601 agacgccgtg atcggcacac ataaccagta ccgttttttt gcccacatgc ggtatgccat
     6661 tcaaccccgg cattcctgcc agttgtatgg caagcgcctc cagccttccc aggctaccaa
     6721 caggtttgag taacccgtca atatgccgtt gtgcacgcga catagcggca ggatcgatag
     6781 cagggatcgt attcagtaaa tcggcaagtg tttgcatgtc acgtctcttt atagcagtgc
     6841 cagcaggaag accagttcac caagctctat ggctgctccc agcgtatcgc ccgtttgccc
     6901 gcccagcgta cgtttgagaa gctgaccgag gatgaaaatc gccaccatcg tcaccaccat
     6961 agcagccaca ccatgcatac ccggcaataa tacggcagca aaaatagcgg ctaagccgag
     7021 tgtgacgcag gtttgtcgcc catcaatttt gccaatgaac acattgccaa gcccttcttc
     7081 ccgcgcataa cgatgacgat acatcaataa tgcggcagtc ccgcggctga ccgcacatgc
     7141 tgccgccagc gatgcaagga tcggttcgcc acgcagagcc aactcgctta acaccagaat
     7201 ctttgccagt accacaaaaa tcaatgccag accgccgtgg gtgcctaaac ggctatcacg
     7261 catgatttcc aacatgcgat cgcggctacg tgcagaaaat acgccatcac aggtatcagc
     7321 gaggccgtcc agatggaatc ccccggtcat cagcgccagc acaagtacgc taaacagtgc
     7381 cgccagtggt gcgccacacc atgcctgcag caccatgaag accagcccgc taatcgcgcc
     7441 aagcaataat ccaatcaaag gaaaagtaat aataccgcga gaataatgct cgaaatccag
     7501 tccctgggac cagcgacgcg gtacaggcag acgcgtaata aatgagagca tcgcccaaaa
     7561 taatttgctc atttgatttt tactccaata cccgaaacca ccagccatac ttcatttgcc
     7621 gcagcggcca actgctgatt tacccgcccg gcaatatcac gaaaatgtcg tgccagacga
     7681 ctctccggca caatccccat tcccacttcg ttagtcacta atacaacctt tgcggggcaa
     7741 cgttggcagg cagcaatcaa cgactgaatc tcagcattaa tcgcctgttc catcgcctga
     7801 taatcccatt catcagggtc tttatcgccg ccataatcaa acaacagatt agtcaccatt
     7861 gtggtaacgc attccagcaa cacagcctca ttcgggttaa tgtctgcatg aattaattca
     7921 tcaagatgtt gccagcgctc caccgtgcgc cagtgctccg ggcggctttg ccgatgatgt
     7981 tctatccgtg cagccatctc atcatcaagg atttgcgagg tagcgatata cagaacctgt
     8041 gaagagtccc caataagcac ctctgcgtgg cgactcttcc cgctccgtgc gcctcccgtc
     8101 accaaaatca tcataccgac tcctgattca aatgtatgat ggtattcatt gaacagagca
     8161 atggatcccc caccgttgct gaccgcaaaa catttacgcg attaatactg cgcgtaatat
     8221 aattaaaaat ccagcattct caatccatta cga
//
LOCUS       DACAOP010000149         8200 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.149, whole genome shotgun sequence.
ACCESSION   DACAOP010000149 DACAOP010000000
VERSION     DACAOP010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8200
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.149"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            247..918
                     /locus_tag="IT892_004155"
     CDS             247..918
                     /locus_tag="IT892_004155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016241930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HAP3137289.1"
                     /translation="MDKVLDSALLSSANKRKGILAIGAHPDDIELGCGASLARLAQKG
                     IYIAAVVMTTGNSGTDGIIDRHEESRNALKILGCHQTIHLNFADTRAHLQLNDMISAL
                     EDIIKNQIPSDVEIMRVYTMHDADRHQDHLAVYQASMVACRTIPQILGYETPSTWLSF
                     MPQVFESVKEEYFTVKLAALKKHKSQERRDYMRHDRLRAVAQFRGQQVNSDLGEGFVI
                     HKMIL"
     gene            928..2124
                     /locus_tag="IT892_004156"
     CDS             928..2124
                     /locus_tag="IT892_004156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP3137290.1"
                     /translation="MKTWIFICMSIAMLLWFLSTLRRKPSQKKGCIDAIIPAYNEGPC
                     LAQSLDNLLRNPYFCRVICVNDGSTDNTEAVMAEVKRKWGDRFVAVTQKNTGKGGALM
                     NGLNYATCDQVFLSDADTYVPPDQDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHI
                     RATVKLPMIVMKRTLQQLLGGALFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTL
                     VANGYRIRQANRCIVYPQECNSPREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIF
                     PMLLVVLYGVGIYLTTWFNEFITTGPHGVVLAMFPLIWVGVVCVIGAFSAWFHRCWLL
                     VPLAPLSVVYVLLAYAIWIIYGLIAFFTGREPQRDKPTRYSALVEASTAYSQPSVTGT
                     EKLSEA"
     gene            2102..2683
                     /locus_tag="IT892_004157"
     CDS             2102..2683
                     /locus_tag="IT892_004157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012602184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP3137291.1"
                     /translation="MKNYLKLNVKEKNIQIADQVIIDETAGEVVIGANTRICHGAVIQ
                     GPVVIGANCLIGNYAFIRPGTIISNGVKIGFATEIKNAVIEAEATIGPQCFIADSVVA
                     NQAYLGAQVRTSNHRLDEQPVSVRTPEGIIATGCDKLGCYIGQRSRLGVQVIILPGRI
                     ISPNTQLGPRVIVERNLPTGTYSLRQELIRTGD"
     gene            2685..3458
                     /gene="yaiO"
                     /locus_tag="IT892_004158"
     CDS             2685..3458
                     /gene="yaiO"
                     /locus_tag="IT892_004158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiO family outer membrane beta-barrel protein"
                     /protein_id="HAP3137292.1"
                     /translation="MIKRTLLAAAIFSALPAYAGLTSITAGYDFTDYSGDHGNRNLAY
                     AELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTP
                     VFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVDAWQGGVSLYTGPVITSYRYTH
                     YDSSDAGGSYSNMISVRLNDPRGTGYTQLWLSRGTGAYTYDWTPETRYGSMKSVSLQR
                     IQPLTEQLNLGLTAGKVWYDTPTDDFNGLQLAARLTWKF"
     gene            3646..3921
                     /gene="frmR"
                     /locus_tag="IT892_004159"
     CDS             3646..3921
                     /gene="frmR"
                     /locus_tag="IT892_004159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414891.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formaldehyde-responsive transcriptional
                     repressor FrmR"
                     /protein_id="HAP3137293.1"
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
                     VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
     gene            3956..5065
                     /locus_tag="IT892_004160"
     CDS             3956..5065
                     /locus_tag="IT892_004160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase/class
                     III alcohol dehydrogenase"
                     /protein_id="HAP3137294.1"
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
                     FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
                     TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
                     HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
                     AHRGWGQSVIIGVAGAGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
                     IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
     gene            5159..5992
                     /gene="fghA"
                     /locus_tag="IT892_004161"
     CDS             5159..5992
                     /gene="fghA"
                     /locus_tag="IT892_004161"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HAP3137295.1"
                     /translation="MELIEKHVSFGGWQNVYRHYSQSLKCEMNVGVYLPPKAANEKLP
                     VLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
                     YLNATQAPWNEHYKMYDYIRNELPDLVMHHFPATAKKSISGHSMGGLGALVLALRNPD
                     EYVSVSAFSPIVSPSQVPWGQQAFAAYLAENKDAWLDYDPVSLISQGQRVAEIMVDQG
                     LSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
                     R"
     gene            complement(6216..6755)
                     /locus_tag="IT892_004162"
     CDS             complement(6216..6755)
                     /locus_tag="IT892_004162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414888.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2058 domain-containing protein"
                     /protein_id="HAP3137296.1"
                     /translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
                     NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKI
                     FVDKLTQAQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
                     EQDEDDPYADFKVPDDLMW"
     gene            complement(6857..8068)
                     /locus_tag="IT892_004163"
     CDS             complement(6857..8068)
                     /locus_tag="IT892_004163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414887.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-(3-hydroxy-phenyl)propionate transporter"
                     /protein_id="HAP3137297.1"
                     /translation="MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQA
                     FALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRKRILIGSVALFGLFSLATAIAWD
                     FPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGF
                     AGANLAWQTVFWVGGVVPLILVPLLMRWLPESAVFAGEKQSAPPLRALFAPETATATL
                     LLWLCYFFTLLVVYMLINWLPLLLVEQGFQPSQAAGVMFALQMGAASGTLMLGALMDK
                     LRPVTMSLLIYSGMLASLLALGTVSSFNGMLLAGFVAGLFATGGQSVLYALAPLFYSS
                     QIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMS
                     RRSRIQPCADA"
BASE COUNT         2045 a         2102 c         2024 g         2029 t
ORIGIN      
        1 acaaactaaa tcacatctaa atacaatgta taaaacaaaa taactataca taccaaacat
       61 acaaacactt aacatatgaa ttgcatagaa acattaccca gtcgaaccca cgggtctgaa
      121 agcccttgct tttcagttat tagcaacatt taacatttat aaattaacat ctggctgcgc
      181 cagagattac gtctctgagt gcatcgttgt gcttgtagta taataaataa aatggagtgt
      241 cattaagtgg ataaggtttt agattcagcc ctcctttctt cggcaaataa aagaaagggt
      301 atccttgcta ttggcgcaca tcctgacgat atagaattag gctgtggcgc atcgcttgct
      361 cgtcttgcgc aaaaaggaat ttatatcgca gccgtggtga tgactaccgg caactctggc
      421 acagatggaa taatcgatcg ccatgaagaa tcgcgcaacg ccctaaagat attagggtgc
      481 caccaaacta ttcatcttaa ttttgctgac acccgcgctc atttacagct caatgatatg
      541 atttccgccc tggaagacat cattaaaaat caaattcctt ctgatgttga aatcatgcgg
      601 gtatatacca tgcatgatgc cgaccgccat caggatcatc ttgctgttta tcaagcttca
      661 atggttgcct gccgaactat tccgcaaatt ctcggctacg aaaccccaag tacctggctt
      721 tcatttatgc ctcaggtttt tgaatccgtt aaagaagaat atttcacagt caaacttgct
      781 gcattaaaaa aacataaaag ccaggaacga cgcgattata tgcgtcatga tcgcctgcgt
      841 gcagttgcac aatttcgcgg acaacaggtc aatagcgatc tgggtgaagg ctttgtaatt
      901 cataaaatga ttctttgagc aaattgcatg aaaacctgga tatttatctg tatgtccata
      961 gcaatgttgc tatggttttt aagtacgcta agacgtaaac ccagtcaaaa gaaaggctgt
     1021 attgacgcca ttatacctgc gtataacgaa ggcccgtgtc tggcgcagtc actggataat
     1081 ctactgcgta acccttattt ttgccgggta atttgcgtta acgacggctc cacggacaat
     1141 accgaagcgg tcatggcgga agtcaaacgc aaatggggcg accgctttgt tgccgtcacg
     1201 caaaaaaata ccggtaaagg tggtgcgctg atgaatggcc tcaattacgc cacctgcgac
     1261 caggtttttt taagtgatgc cgacacctat gttccgcccg atcaagacgg aatgggctat
     1321 atgctggcag aaattgagcg cggtgccgat gccgtaggcg gcattccctc tactgcgttg
     1381 aaaggcgcgg gtctgttacc gcacatccgc gcgaccgtaa agttgccgat gattgttatg
     1441 aagcgcacgc tacagcagct cctgggtggc gcactgttta ttatcagcgg tgcctgcggg
     1501 atgttccgta ctgatgtatt gcgtaagttc ggtttctcgg atcgtactaa agtcgaagac
     1561 cttgatctca cctggacatt ggtggcaaac ggctaccgta ttcggcaggc gaatcgctgc
     1621 atcgtatacc cacaggaatg caacagcccg cgtgaggagt ggcgtcgctg gcggcgttgg
     1681 attgtgggat acgcggtctg tatgcgcctg cataaaagac ttttatttag ccgcttcggt
     1741 atcttcagta tatttcctat gctgttggtt gtgctttatg gcgttgggat ttatctcact
     1801 acctggttta atgaattcat caccaccggg ccgcatggag tggtgttggc aatgtttccg
     1861 cttatctggg tcggcgtagt ttgtgttatt ggtgctttta gcgcctggtt tcatcgttgc
     1921 tggttgttgg tgcctttagc gccgctttcc gttgtgtatg tattattagc ttatgccatc
     1981 tggattattt atggacttat tgcctttttt actggacgcg aacctcagcg cgacaaaccc
     2041 acccgctatt ccgcactggt ggaagcgtca accgcttatt cccaaccttc tgtcacagga
     2101 actgaaaaac tatctgaagc ttaatgttaa agagaaaaat attcagattg cagaccaggt
     2161 aattattgat gaaactgcag gtgaagttgt tatcggcgcg aatacccgta tttgtcatgg
     2221 tgccgttatt cagggtccgg tagtgattgg cgcaaactgc ctgataggta attatgcgtt
     2281 tattcgtcct ggcacaataa tcagcaatgg cgtaaaaatt ggttttgcca ccgagattaa
     2341 aaatgcggtt attgaagcgg aagcaacgat tggtccgcaa tgttttattg ccgactcggt
     2401 agttgcaaac caggcatatt taggcgcaca agtacgtacc agtaatcatc gtctggatga
     2461 acagcccgtg tctgttcgaa ctccagaggg aattatcgct accggatgcg ataaattagg
     2521 ttgttatatc gggcagcgtt cacgccttgg cgtacaagtt attattttgc ctgggcgaat
     2581 tatttccccg aacacgcaac ttggcccgcg cgtgattgta gaacgtaatt tacctaccgg
     2641 aacttattca ctccgacaag aacttatccg tacaggagat taaaatgata aaacggacgt
     2701 tattagcggc ggccattttt agcgcattgc ccgcttatgc cgggttaact tccattaccg
     2761 cgggctacga ttttaccgat tattctggcg atcatggcaa ccgtaattta gcgtatgctg
     2821 aactggtggc gaaagttgaa aacgcaacgc tgctttttaa tctttcccag gggcgtcgtg
     2881 attatgaaac tgaacatttc aatgccactc gcggtcaggg tgcggtctgg tataaatgga
     2941 ataactggct gacaacccga acgggtattg cctttgcgga taatacgccg gtctttgccc
     3001 gccaggattt tcgtcaggat attaacctgg ccctgttacc aaaaacgctt ttcacgaccg
     3061 gttatcgcta cactaaatat tacgatgatg tcgaagtcga tgcctggcaa ggcggcgtat
     3121 cactctatac tggcccggtg atcaccagct accgctatac ccattatgac tccagcgatg
     3181 caggtggtag ttatagcaat atgatttccg tgcgtctgaa tgacccgcgc ggcactggtt
     3241 atacgcaact atggctaagc cgcggaacag gtgcttacac ctatgactgg acgccagaaa
     3301 cacgctacgg cagcatgaag agcgtcagtc tgcaacgtat tcaaccgctg actgagcaac
     3361 ttaatctcgg gctgacggca ggtaaagtgt ggtacgacac cccaaccgat gattttaacg
     3421 gtctgcaact tgcagcccgt ctgacctgga aattctgatt ccttctgccg cccgctatcc
     3481 ggggcggcct tccctgccga ttagcccccc cccctttcct ctttgttttc cgaccacatt
     3541 caccggataa attttattct ccagtgttat atactatagg ggggtatgca ttgacatata
     3601 gaataccccc ctatagtata ttgcatgcag atgatgaggt gcgaaatgcc cagtactccg
     3661 gaagagaaga aaaaggtcct tactcgagtt cgtcgtattc gggggcagat tgatgctctg
     3721 gaacggtcgc tggagggtga tgccgaatgc cgtgccatac tccaacagat cgctgccgtt
     3781 cggggcgcgg ctaatgggct gatggcagaa gtgcttgaaa gccatatccg ggaaacgttt
     3841 gaccgaaatg actgctacag ccgcgaagtc agccaatccg ttgacgacac tattgaactg
     3901 gttcgtgcct atcttaaata gctgaatcta ttaccatatt gaggaagagc gagagatgaa
     3961 atcacgtgct gccgttgcat ttgctcccgg taaaccgctg gaaatcgttg aaattgacgt
     4021 tgcaccaccg aaaaaaggtg aagtgctaat taaagtcacc cataccggcg tttgccatac
     4081 cgacgcattt accctctccg gcgatgaccc ggaaggtgta ttcccggtgg ttctcggtca
     4141 cgaaggggcc ggcgttgtgg ttgaagtcgg tgaaggcgta accagcgtca aacctggcga
     4201 ccatgtgatc ccgctttaca ccgcggagtg cggcgagtgt gagttctgtc gttctggcaa
     4261 aactaacctc tgtgttgcgg ttcgcgaaac ccagggtaaa ggcctgatgc cagacggcac
     4321 cacccgtttt tcttacaacg ggcagccgct ttatcactac atggggtgct ctacattcag
     4381 tgaatacacc gtagtcgcgg aagtgtctct ggcaaaaatt aatccagaag caaaccatga
     4441 acacgtctgc ctgctgggct gtggcgtgac caccggtatt ggcgcggtac acaacacagc
     4501 taaagtccag ccaggtgatt ctgttgccgt gtttggtctt ggcgcgattg gtctggcagt
     4561 ggttcagggc gcgcgtcagg cgaaagcggg tcggattatc gctatcgata ccaacccgaa
     4621 gaaattcgat ctggcgcgtc gcttcggtgc taccgactgc attaacccga atgactacga
     4681 caaaccgata aaagatgtcc tgttggatat caacaaatgg ggtatcgacc atacctttga
     4741 atgcatcggt aacgtcaacg tgatgcgtgc ggcgctggaa agtgcgcacc gcggctgggg
     4801 tcagtcggtg atcatcgggg tcgcgggtgc cggtcaggaa atctccaccc gtccattcca
     4861 gttggtcact ggtcgcgtat ggaaaggttc cgcgtttggc ggcgtgaaag gtcgttccca
     4921 gttaccgggc atggttgaag atgcgatgaa aggtgatatc gatctggaac cgtttgtcac
     4981 gcataccatg agcctggatg aaattaatga cgccttcgac ctgatgcatg aaggcaaatc
     5041 cattcgaacc gtaattcgtt actgatttcc cgcaggttta ccccgtccac ttcaggcggg
     5101 ggttcttaat actctccccg ggcagccgtc cgggggatta accctgagat aatgactgat
     5161 ggaactcatt gaaaaacatg tcagctttgg cggctggcaa aatgtgtatc ggcattattc
     5221 ccaatcactg aaatgtgaaa tgaatgtcgg cgtctatctc ccaccaaaag ccgcgaatga
     5281 aaaattgccg gtgctgtact ggctttcagg cctgacctgc aacgagcaga atttcattac
     5341 taaatcgggg atgcagcgtt acgcggctga gcacaacatt attgttgttg cgccggacac
     5401 cagtccgcga ggcagtcatg tcgcagatgc tgaccgttac gatctcgggc aaggtgccgg
     5461 gttttacctg aacgcgacgc aagcgccgtg gaatgaacat tacaaaatgt atgactatat
     5521 ccgcaacgag ctgccggatt tagtgatgca tcattttccg gcaacggcca aaaagtctat
     5581 ctctggtcat tctatgggcg ggctgggcgc gctggtgctg gcgttacgta acccagatga
     5641 atatgtcagc gtctcggcgt tttcgcccat tgtctcccca tcgcaagtgc cgtggggaca
     5701 gcaagccttt gctgcatatc ttgctgaaaa taaagatgcc tggttggatt acgacccggt
     5761 gagtcttatt tcacaaggtc aacgcgttgc ggaaatcatg gttgatcagg ggttgagtga
     5821 tgatttttac gcagaacagc tgcggactcc aaatcttgaa aagatctgcc aggagatgaa
     5881 tatcaagacg ttaatccgtt atcacgaggg ttatgatcac agctattatt ttgtctccag
     5941 ttttattggc gagcatattg cctaccacgc caataaactg aatatgcgtt gataatagca
     6001 cgactgccgg atgcggcgtg aacgccttat ccggcctaca cttcgcccgt aagccgtagg
     6061 cctgataaga cgcgcaaagc gtcgcatcag gcatggcgca cgactgccgg atgcggcgtg
     6121 aacgccttat ccggtctaca cttcgcccat aaaccgtagg cctgataaga cgcgcatagc
     6181 gtcgcatcag gcatctgcgc acgacttatc tatgtttacc acatcaaatc atcaggcact
     6241 ttgaagtcgg catacgggtc gtcttcatcc tgctcttcgg cgctgagcgc gctgtgcaac
     6301 actatactgc tggcatcgcg ctgagcaatt ttatcggcaa cgctggcggg aataatggcg
     6361 tattcacctt cgctattgtt atcgaccaac aagcgggcaa tcgccagacg accattaatc
     6421 aactgcgcct gtgtgagctt atcgacaaaa atcttcttaa tcagattgcc gtcagtgaag
     6481 ttaaaaccaa tatcgccatt ggcaatggtg attcggttca tttcaataag ctgcttcacc
     6541 tgagctttat attctttcgc caacgccgct tgtttttgct gttcgctaag ctgtttatca
     6601 cgctcaagct gtgccttttt attttcttct accgccgccc gagcttcacg cgcctgaacg
     6661 cgcgattttt tcgccgttct ctccaccttc gccgcttttt tgctggtgac taatcctgct
     6721 ttgagcaact gctcttgtaa ggtaagtttt gccatctttg tttccaaacc cgctgaataa
     6781 tttttagcga gtatacctgt aaacgccgta ggtgtattgg ggtgaagtcc ctttcgcccc
     6841 tgcctaataa ggcacgtcag gcatcggcgc acggctgtat tcgtgatctc cggctcatca
     6901 aaataaacac cgccaaccca gcaacaagaa tacccggtgc agaagcggcc attacgccga
     6961 ccgtgccagt gcctaatgcc agcattttcc cggccagtaa cggaccgctc atagccccca
     7021 gacgccctac cgccacggct gttcccacac ctgttgcgcg gatctgcgaa ctgtaaaaca
     7081 acggtgccag ggcatacaaa acgctttgcc cacctgtcgc aaacaacccc gcgacaaatc
     7141 ccgccagcaa cataccgtta aatgacgaca ccgttccaag cgccagcagc gaagctaaca
     7201 tgccgctata aatcagtagc gacatggtta ctggacgcag cttatccatc aatgcgccca
     7261 acattaacgt cccgcttgcc gcccccattt gcagggcaaa catcacccct gccgcctgcg
     7321 atggctggaa tccttgctcc accaaaagta gcggtagcca gttgatcaac atgtagacca
     7381 ccagcagagt gaagaaataa cacaaccaca gcagcagcgt cgcggttgcc gtttctggcg
     7441 caaataaggc acgcagtggt ggcgcagact gtttttcgcc agcgaaaacc gccgactccg
     7501 gcagccagcg cattaatagc ggcaccagaa tcaacggcac cacaccacct acccaaaaca
     7561 ccgtttgcca tgctaagttt gcccccgcga aacccagtgt cgccgccagc gccgcgccaa
     7621 tgggaacacc gcaatacatc aggctcactg ccgtcccacg aaaacgtgga cccgcggctt
     7681 cagacgtcag ggcgataaga ttcggcaacg ccgcccccag cccgacaccg gtcatcagcc
     7741 gcgcaaagac cagtgagggg aaatcccagg caatcgccgt tgccagtgag aacaaaccaa
     7801 acagcgcaac tgagccaatc aaaatgcgct tgcgaccata acggtccgcc agcattccgc
     7861 caaccaacgc gccgggtagc aaaccgagta ttccggcgct aaatatccag cccatttgca
     7921 ttttatcgag tgcgaaagcc tgggcgatgc cacccgccgc aatgccagcc gcctgaagat
     7981 ccagcccttc catcagagcg accaaaaaac aaagcccgat ggtcagcatc aggcgggatg
     8041 aagatgatga aggggtacga gtcgacataa gatgaacctc gttgcgagtg caggtgaatc
     8101 gcgactgata cattgccagc cgcgtaatca gaactattta atgactgcct acgggcgaaa
     8161 tgtaggccgg acaagacgtt tatcgcatcc ggcagtcgtg
//
LOCUS       DACAOP010000150         8184 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.150, whole genome shotgun sequence.
ACCESSION   DACAOP010000150 DACAOP010000000
VERSION     DACAOP010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8184
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.150"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..122
                     /locus_tag="IT892_004164"
     CDS             <1..122
                     /locus_tag="IT892_004164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF905 domain-containing protein"
                     /protein_id="HAP3137298.1"
                     /translation="FSREQAVAVKTAYRNVFTEDDQGTYSRLVIRNAEGQLRW"
     gene            277..1095
                     /locus_tag="IT892_004165"
     CDS             277..1095
                     /locus_tag="IT892_004165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HAP3137299.1"
                     /translation="MRLASRFGYANQIRRDRPLTHEELMHYVPSIFGEDRHTSRSKRY
                     AYIPTITVLESLQQEGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVCVPHRGNVVEKVIEGAYEVVGVFD
                     RIEEKRDAMQSLVLPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     TYQTIQENMLKGGISGRSAKGKRIHTRAIHNIDTDIKLNRALWVMAETLLESLR"
     gene            1437..1910
                     /locus_tag="IT892_004166"
     CDS             1437..1910
                     /locus_tag="IT892_004166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HAP3137300.1"
                     /translation="MKTLSQNTTSSACAPETDLQQLVATLVPDEQRISFWPQHFGLIP
                     QWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNAMNGN
                     RAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRIID"
     gene            1926..2402
                     /locus_tag="IT892_004167"
     CDS             1926..2402
                     /locus_tag="IT892_004167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HAP3137301.1"
                     /translation="MQQLSFLPGEMTPGERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHRSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGSQVFSFAEHGLL"
     gene            2465..2686
                     /locus_tag="IT892_004168"
     CDS             2465..2686
                     /locus_tag="IT892_004168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HAP3137302.1"
                     /translation="MKIITRGEAMHIHRQHPASRLFPFCTGKYRWHGSAEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            2849..3217
                     /locus_tag="IT892_004169"
     CDS             2849..3217
                     /locus_tag="IT892_004169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HAP3137303.1"
                     /translation="MSDTLSGTTHPDDNDDHPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGRFRDADAYPLDQAFPLLMKQLELMLTSGELNPRHQHTVTLYAKGLTCEAD
                     TLGSCGYVYLAVYPTPETKK"
     gene            3307..3684
                     /locus_tag="IT892_004170"
     CDS             3307..3684
                     /locus_tag="IT892_004170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HAP3137304.1"
                     /translation="MKTLPDTHVREVSCCPSPVTIWQTLLTRLLDQHYGLTLNDTPFV
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQSGFSACTHSQLINSIDILRARRATG
                     LMTRDNYRTVNNITLGKHPEAKR"
     gene            3681..3884
                     /locus_tag="IT892_004171"
     CDS             3681..3884
                     /locus_tag="IT892_004171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137305.1"
                     /translation="MKLALTLEADSVNVQALNMGRIVVDVDGVNLAELINKVAENGDS
                     LRVVDERDSTETPATYASPHQLL"
     gene            3897..4010
                     /locus_tag="IT892_004172"
     CDS             3897..4010
                     /locus_tag="IT892_004172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HAP3137306.1"
                     /translation="MQGIVPLTTETALLSCIKQAREDVLTLRHLQLLHQNQ"
     gene            4169..5197
                     /locus_tag="IT892_004173"
                     /pseudo
     CDS             4169..5197
                     /locus_tag="IT892_004173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008216294.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            5468..5638
                     /locus_tag="IT892_004174"
                     /pseudo
     CDS             5468..5638
                     /locus_tag="IT892_004174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001596174.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization protein"
     gene            5651..5833
                     /locus_tag="IT892_004175"
     CDS             5651..5833
                     /locus_tag="IT892_004175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein"
                     /protein_id="HAP3137307.1"
                     /translation="MNHPVTGVVTKADLASMEHISLVKCWLREAGAHNVLVTSAVNNN
                     GVTELFALQHTEEGCC"
     gene            complement(5934..6263)
                     /locus_tag="IT892_004176"
     CDS             complement(5934..6263)
                     /locus_tag="IT892_004176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF496 family protein"
                     /protein_id="HAP3137308.1"
                     /translation="METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLL
                     LDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERRDISKKLKAMGE
                     MKNGEAK"
     gene            complement(6435..7493)
                     /locus_tag="IT892_004177"
     CDS             complement(6435..7493)
                     /locus_tag="IT892_004177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP3137309.1"
                     /translation="MRADKSLSPFEIRVYRHYRIVHGTRVALAFLLTFLIIRLFTIPE
                     STWPLVTMVVIMGPISFWGNVVPRAFERIGGTVLGSILGLIALQLELISLPLMLVWCA
                     AAMFLCGWLALGKKPYQGLLIGVTLAIVVGSPTGEIDTALWRSGDVILGSLLAMLFTG
                     IWPQRAFIHWRIQLAKSLTEYNRVYQSAFSPNLLERPRLESHLQKLLTDAVKMRGLIA
                     PASKETRIPKSIYEGIQTINRNLVCMLELQINAYWATRPSHFVLLNAQKLRDTQHMMQ
                     QILLSLVHALYEGNPQPVFVNTEKLNDAVEELRQLLDNHHDLKVVETPIYGYVWLNME
                     TAHQLELLSNLICRALRK"
     gene            complement(7691..8164)
                     /gene="sbmC"
                     /locus_tag="IT892_004178"
     CDS             complement(7691..8164)
                     /gene="sbmC"
                     /locus_tag="IT892_004178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor SbmC"
                     /protein_id="HAP3137310.1"
                     /translation="MNYEIKQEDKRTVAGFHLVGPWEQTVQKGFEQLMMWVDSKNIVP
                     KEWVAVYYDNPDETPAEKLRCDTVVTVPNNFTLPENSEGVILTEISGGQYAVAVARVV
                     GDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGDWDIEMYVAVQPKHH"
BASE COUNT         2090 a         2142 c         2011 g         1941 t
ORIGIN      
        1 ctttctcacg cgaacaggct gttgccgtca aaacagctta ccgcaatgtg tttactgaag
       61 atgaccaggg aacatattcc cggctggtta tccgtaatgc tgaaggtcag ttgcgctggt
      121 gatgccggaa cacagcttaa tactcagctc gccagttaag ggcttctcag acaataaacg
      181 tcattcattt catctgtcag gccgcgtctt ctccgggaga cgcagctttt tcatttatta
      241 caccagtaaa tcgtaaccac cgataaggag caaattatgc gactagccag tcgttttggt
      301 tatgcgaacc agatacgccg tgaccgtccg ctgacacacg aagaactgat gcactatgtt
      361 cccagtattt tcggtgaaga ccggcatact tcccgcagta aacgatatgc gtacattccc
      421 accatcaccg tactggaaag cctgcagcag gaaggttttc agccattctt cgcctgccag
      481 acccgcgtgc gcgacccggg ccgccgggga tacacaaaac acatgctgcg tctgcggcgg
      541 gccggagaga taaacggaga acatgtccct gaaattattc tgctcaactc tcatgacggt
      601 acctccagct accagatgct gccgggttac ttcagattcg tctgccagaa tggctgcgtc
      661 tgcggtcagt ctctggggga agtgtgtgtt ccacaccggg gaaatgtggt ggagaaagtt
      721 atcgaagggg cttacgaagt ggtgggggtt tttgaccgga ttgaggaaaa gcgtgatgcc
      781 atgcagtcgc tggtcctgcc gccaccggca cgccaggcgc tggcacaggc ggcactgact
      841 taccgttatg gtgacgaaca tcagccagtc accaccgctg acattctgac gccacgacgc
      901 cgggaggatt acggtaagga cctgtggagt acttatcaga ccatccagga gaatatgctg
      961 aaaggcggga tttccggccg cagtgcaaaa ggaaaacgta tccacacccg tgccattcac
     1021 aacatcgaca ccgatattaa gctcaaccgc gcattgtggg taatggcaga aacgctgctg
     1081 gagagcctgc gctgatgcag catgtccctg aaggcgtgat tcaggcacca gaatcacccg
     1141 acgccccgga ggcgctgccg gggtgtcgtt ccatttctga tgatgacctg tgcgcctggt
     1201 gtacccgtct gctttaccgt cccggagaaa tcagtctgtg cagactgagt atacaggcaa
     1261 tggcatctgg ccatccgtct gtgaccggaa cggttacgcg tacggctgtc cggaatttca
     1321 gccgaatatc attcatccct gatattaccg ggtcatcacg gtcagtgatg aacgtgatgt
     1381 tgccaggtcc cgacctttac tccctctcat ttattcacat tacaaggatt tcatacatga
     1441 aaacattgtc tcagaacacc acctcttcgg cctgtgcacc ggagactgac ctgcaacaac
     1501 tggttgccac cctcgtccct gatgaacagc gcatcagctt ctggccgcag cactttggcc
     1561 tcattccaca gtgggtgacc ctggagcccc gtgtcttcgg ctggatggac cgtctgtgcg
     1621 aagactactg cggtggtatc tggaatctgt acaccctgaa caacggcggg gcatttatgg
     1681 cacccgaacc ggatgacgat gatgacgaaa catgggtact gttcaatgcc atgaacggta
     1741 accgcgctga aatgagtccg gaagctgccg gcattgctgc ctgtctgatg acgtacagtc
     1801 atcatgcctg tcgtacggag tgttatgcca tgacggtcca ttattaccgg ctgcgggatt
     1861 acgccctgca gcatccggaa tgcagcgcca ttatgcgcat catcgactga atggagagaa
     1921 gtacaatgca acagctttcc tttctgcccg gagagatgac gcccggcgag cgcagcctca
     1981 ttcaacgggc cctgaaaacc ctggaccgcc atcttcatga acccggcgtg gccttcacct
     2041 ccacccgtgc ggcacgagaa tggctgattc tgaacatggc gggactggag cgtgaagagt
     2101 tccgggtact gtatctgaac aaccagaatc agctgattgc cggtgaaacc ctcttcaccg
     2161 gcaccatcaa ccgcacggaa gtccatcccc gtgaagtgat taaacgcgcc ctgtatcaca
     2221 atgccgctgc tgtggtgctg gcacacaatc accggtccgg tgaagtcaca cccagcaagg
     2281 cagaccgcct tatcacggaa cgtctggtac aggcactggg cctggtggat atccgggtgc
     2341 cggaccatct gatagtcggt ggcagccagg ttttctcctt tgccgaacat ggtctgcttt
     2401 aacccgtcac aactacatca cacctgtttt cacttttatc ttctgtcttc agaggtatcc
     2461 caccatgaaa atcatcaccc gtggcgaagc catgcatatt caccgtcagc atccggcatc
     2521 ccgtcttttt ccgttctgta ccggcaaata ccgctggcac ggcagtgctg aagcgtatac
     2581 cggtcgtgaa gtgcaggata ttcccggtgt gctggccgtg tttgcagaac gccgtaagga
     2641 cagttttggt ccgtatgtcc ggctgatgag cgtcaccctg aactgatgtt ccgtcacccg
     2701 gaaaacgagt acgactggct gagctcagac gccgctgtgg atgaggtcct gctcatcaac
     2761 gaatacacct ttaccgaagc cggtctgcgc gccggctgac ccgtcatcgt taaactatca
     2821 ttcaccgatt ttctgtgagg attttatcgt gtcagacaca ctttccggga caacgcatcc
     2881 cgatgacaat gacgaccatc cctggtgggg actaccctgc acagtgacgc cctgtttcgg
     2941 cgcccgtctg gtgcaggagg gtaaccggtt gcattacctt gccgaccgtg ccggtatcag
     3001 aggccggttc agagatgcgg atgcgtaccc tctggaccag gcctttccgc tgctgatgaa
     3061 acaactggaa ttaatgctca ccagtggtga actgaatccc cgccatcagc ataccgtgac
     3121 actgtatgcg aaggggctga cctgtgaagc cgacaccctc ggctcctgtg gttacgttta
     3181 tctggctgtt tatccgacac ctgaaacgaa aaagtaaacc accggaataa ccttctgctc
     3241 cggcctggtg ttttcaccac gccactgtcc cattttttat ctctgcatat caggaaaatc
     3301 ttcagtatga aaacattacc cgacacgcat gtacgggagg tatcgtgctg cccgtctccc
     3361 gtcaccatct ggcagacact gctcacccga ctgctggacc agcactacgg ccttacgctg
     3421 aatgacacac cgttcgtgga tgaacgtgtg attgagcagc atattgaggc aggcatttca
     3481 ctgtgtgacg cggtgaactt tctcgttgaa aaatacgcgc tggtacgtac cgaccagtcg
     3541 ggattcagcg cctgtaccca ctctcagtta ataaacagca tcgatatcct ccgggctcgc
     3601 cgggcaacag gcctgatgac ccgcgacaat tacagaacgg taaataacat taccctgggg
     3661 aagcatccgg aggcgaaacg atgaaactgg ccctgacgct ggaagccgac agcgttaacg
     3721 tgcaggcgct gaacatgggg cgcattgtcg ttgacgtcga tggtgttaat ctcgctgaac
     3781 tgattaacaa ggtcgctgaa aacggtgatt cactccgcgt ggtggatgaa cgtgactcta
     3841 ccgaaacacc ggcaacttat gccagccctc accagttgct gtaagacaat gcagtgatac
     3901 agggtatagt gccattaacc acagaaacag cactgttgtc ctgtattaag caggcaagag
     3961 aagatgtcct taccctgcgc catctgcagc ttctgcacca gaaccagtga atctcactca
     4021 acaggcttca tttcccctga cgccagcctg aatacagctg gcgttttcat ttataaacag
     4081 aaaggaaaac cgataataat ggaatggacg cccctaccat gaagcaacgg taggatatta
     4141 ctgataaacc ttccagtgga ggtgcgttat ggccgtttta acgattagca ttgacctgac
     4201 aaaaaatgaa ttccaaatcc acggtctggg taggaacaga aaaatctaag ctcagaaaac
     4261 ggattaaacg ttccctgatg cccgtattct tcgcgaatat gtcttcctgt cggattggga
     4321 tggaggtctg cgccggagcg cgtcattagt gagaatgctg tctacttagg ggcataatgt
     4381 cagactaatg cccgcgattt gtaaagccat atgtgaaaac aaacaagaat gatatggctg
     4441 ctgccgaggc catctgtgaa gccgttaccc gacctaatat gcggtttgtc agcatcaaga
     4501 cgcctgagca gtagtcatta ctgtcttttc atcgtgccca gacggggttt gttaaatcaa
     4561 ggactgcgca gataaaccag atcagaggat tactggctga atttggcatc gttctcccgc
     4621 ccgacactgt agcgatcagt cgtcatgtcc ctgccctgct tgaagacgcg gaaaactgtt
     4681 taacaatgcc gttcagacag ctgtcgtcct atctctaatg aaaatgtgaa acaactgagc
     4741 gtacacattg aaaccataga agccgtgagc aacgaacacg tcgggaacga cgaactgtgc
     4801 aggaaaattg ccaccatttc ggggattgct attcttacca ccactgcaat tgtcagcacc
     4861 gggtagtatc ggcttcaaaa accggcgtca gcttgctgca tggcttggac tggttccccg
     4921 acagtgcttc agcgtaggta aaaacacgct ggggtctatc agtaaacggg acgatgtcta
     4981 tatcagaacg ctactgttcc atggtgcgaa gacagtgtca aacgccagaa agggcagaca
     5041 ggtccaggaa agctggctgg gcagaccagt ctcgcggcgg aataaaaatg ttgccaccgt
     5101 agcgctgaac aacaaaaatg ccagagtgct ctgggtattg ctaaccaacg ataaagagat
     5161 ttcaccagaa gaagtgatgg tagctgcata tatgtaaatg aaactacttc tgtctgttga
     5221 aaaataaaac caacctactg attgctaagg ataaacgagt attaaaggcc agactgataa
     5281 gaccgcgact aagtgaacct gtatctgaca tggcatagct tcgctaatgt gtcatcatga
     5341 ttaggactaa atctgtgaat tcctttagga agcacggaca caggccaatc tgagtccata
     5401 tgtatgattg gaatcttaca cagatgactt tttgacacgg ggacttggca aacaggagcg
     5461 accatgtatg tcagatatta caatctcact tccgaaagaa gtcaacgggc acgttatctg
     5521 ttcaaccaga atccgacaca ttctggctat acgaaagagc atacttatgc aaatctatat
     5581 gcttttccgg caacaagcag gaatctcagc gctgaggcag gaattagagg taaaaacgcc
     5641 ctaccgggcc atgaatcacc cggtcactgg agtagtaacc aaagcagatt tagccagcat
     5701 ggaacacata tctttggtga aatgttggtt acgggaagct ggagcgcaca acgtgttagt
     5761 aaccagtgcg gttaataaca atggagttac agaacttttt gccttgcagc atacagaaga
     5821 aggctgttgc taatttcgat aggttctcag atgagaatga tgacggtgat acacagataa
     5881 gaatcaatga gcaatgaggg ttgccgggca accctcattg aataaaacag gaattacttc
     5941 gcttcgccgt ttttcatttc gcccatagct ttcagctttt tggagatatc gcggcgttct
     6001 ttggagagct cggcattttt gatgatgtaa tcgtcaacgc gatcttcata gtcacctttc
     6061 atgctggcga tgatgccctg gattgcttca acgctcatcc ctggcttgat gtaatcgctc
     6121 aggttatcca gcaacaggac gcgcttctgg ttgtcacgga tctttttctc aacgtcctga
     6181 atttcacgtt gcagtttgtt cttacgacgg aacagacgaa caaattccag tacgtcctgg
     6241 aatgaaggct tggtagtttc catttttata cccctgataa tgtgagagtc ggattcgttt
     6301 aagcaaccgc tattcgttag ggccaacatt actcatagct gccgcagatg acaatgcttt
     6361 tatccctttt cactatcata ccctttatcc ttgctgaatc gaagcagcag caagatgatt
     6421 ctgaagttca ggaattattt gcgcaaggcc cggcaaatca gattcgatag caactcaagc
     6481 tgatgtgccg tttccatgtt cagccacaca taaccataga ttggtgtttc cacgactttc
     6541 aggtcatggt ggttatcgag caactgacgc aactcttcca cagcatcgtt caatttttcc
     6601 gtattgacaa aaaccggctg cggattacct tcgtacagcg catgaacaag gctcagcagt
     6661 atttgctgca tcatgtgctg ggtatcacga agtttttgcg cattcaataa cacgaaatgg
     6721 ctggggcgcg tggcccagta tgcattgatt tgcaactcca gcatacaaac cagattgcga
     6781 ttaatggtct ggataccttc atatatcgat ttgggaatac gggtttcttt gctggcgggc
     6841 gcaatcagcc cacgcatttt cacggcatcg gtcagcagtt tttgtagatg gctttccaga
     6901 cgtgggcgtt cgagtaagtt cggtgagaat gcagattgat agacccgatt atactcggtc
     6961 agacttttcg ccagttgaat gcgccagtgg atgaacgccc gttgtggcca gataccggta
     7021 aacaacattg ccagtaaaga gccgaggatc acatcgccgc ttcgccataa cgccgtatca
     7081 atttcacctg tcggggaacc cacaacaatt gccagcgtca ccccaatcaa taatccttga
     7141 tacggtttct tgcccagcgc cagccaaccg caaagaaaca tcgccgccgc gcaccagact
     7201 aacatcagcg gtaacgaaat taactccagt tgcagagcga taagacctaa aatcgacccc
     7261 aacaccgtac cgccaatacg ttcgaaggcg cgagggacaa cgttccccca gaacgagatt
     7321 ggccccataa tcaccaccat ggtgaccagc ggccaggtgc tttccgggat agtaaacagg
     7381 cggataatga gaaaagtgag caggaatgcc agcgcgaccc gagtaccatg cacaatgcgg
     7441 taatggcggt atacccggat ttcaaacggg cttaatgact tatcggcacg cacgcagaaa
     7501 ctccgtaatg aagattaaaa gcgctcataa cacatctgtc ggccagaagg cgcgcctctg
     7561 agttatccga cggacatacc gggaacagtg taatttcccg gcaggagcga aaaatttgaa
     7621 aggcgcatct tactcttttc gctttcaaaa aaagagtggt cttcgcgtta acacaccgcc
     7681 ctgagatgaa ttagtgatgt tttggctgca ccgcaacata catttcgata tcccagtccc
     7741 catcttccgc gccattgttc aagtaaacct cgaagcaggg ctttggtaac atttcataag
     7801 cactgtcctg caagaggcta ttaaagaact gataccaggg tttagcaaaa tcatcaccga
     7861 ctacacgagc caccgccacc gcatactgac cacctgaaat ttctgtcaga atgacgccct
     7921 cactgttttc ggggagcgta aagttattcg gtaccgtcac gacggtgtcg cagcgtaatt
     7981 tttcggcggg tgtttcatct ggattgtcgt aatagacagc aacccactcc ttcggcacaa
     8041 tatttttgct atctacccac atcatcaact gctcaaaacc tttttgtacc gtctgctccc
     8101 acgggccaac gagatggaaa cctgcaacgg tacgtttatc ttcctgctta atctcgtagt
     8161 tcatgacgcc tccattaaca ctgt
//
LOCUS       DACAOP010000151         7837 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.151, whole genome shotgun sequence.
ACCESSION   DACAOP010000151 DACAOP010000000
VERSION     DACAOP010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7837
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.151"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(52..192)
                     /locus_tag="IT892_004179"
     CDS             complement(52..192)
                     /locus_tag="IT892_004179"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137311.1"
                     /translation="MSDTTLLIAGSLIYSMIFCVVMTAAHTIMLSRKLRKLEKQIKEQ
                     SS"
     gene            complement(211..738)
                     /locus_tag="IT892_004180"
     CDS             complement(211..738)
                     /locus_tag="IT892_004180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001570842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAP3137312.1"
                     /translation="MRLHTRTKAFSLLEMMLVLAVAAVLAIGVFMIYPKVSSSQKIDS
                     DMKLLSTINGGIKSIFASKANYDGLSTDMVIKAQLVPEDNVEDGQIWNAWGATVLIDA
                     WYDGSYRIGFENISPDACPKFISQAGASFFKIQVEGTEVKNTADNKDFNVETAAQACA
                     SVSDNRPVTVYFYDK"
     gene            complement(750..1289)
                     /locus_tag="IT892_004181"
     CDS             complement(750..1289)
                     /locus_tag="IT892_004181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001515498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAP3137313.1"
                     /translation="MKLIKIQNKGFSLLEILLVLAVAAALVIGAFVLYPKLVASQKIE
                     KESKNITTLQAGVKALYAGRSRLSGLSPTVLIQSKNVPDNMVQDGKLINEWKGEVDIA
                     YQGNHGKYSITYNGVPAEACSKFITGVSGNFVSITIYNGGSGGDVKNDEEGKPLDVAK
                     TASACGSDTVSTIMFSSII"
     gene            complement(1264..1671)
                     /locus_tag="IT892_004182"
     CDS             complement(1264..1671)
                     /locus_tag="IT892_004182"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137314.1"
                     /translation="MAKKRKYKCKNCKQLEQKINHANQQEEILSTIAILFMFFMIFAI
                     PVINSKIINASNENSINLAESKNRESEKKVMELLDMKIQVCKMEGELQPGIYSFHLDS
                     DTSCDTYKREYRKLEEKYKSTKGNDYEINKNTK"
     gene            complement(1684..2013)
                     /locus_tag="IT892_004183"
     CDS             complement(1684..2013)
                     /locus_tag="IT892_004183"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137315.1"
                     /translation="MKNKIKNLSVCSKERMVKESILKEGLPDINSLFSFNHPMATYFY
                     TMEDMEESSWLIEYNDSEERKFLLNEFGFKGKLSLLSVNEQNKLLLKIISNDRANSLP
                     TIKRKRL"
     gene            complement(2152..2778)
                     /locus_tag="IT892_004184"
     CDS             complement(2152..2778)
                     /locus_tag="IT892_004184"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137316.1"
                     /translation="MENILSKKQKKELKKTYLNTERKIRNSIVSNRKGFYCGIAVLAV
                     LTAYSLLKPKEQQTVIPQVNQDYENCMSWNRSNSINRKQYLSPVQINGVVVDSAVNDF
                     CAADKNRNRVSSEQNGLWLMNFENCMQQLQPDRMFIETMNLTVFDKKYTGVKKETVNQ
                     CVRYAATNNKYDIYDNYLYAVYMAGTFIKSDSVDDVIFSIKTNFYKQI"
     gene            complement(2899..3807)
                     /locus_tag="IT892_004185"
     CDS             complement(2899..3807)
                     /locus_tag="IT892_004185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137317.1"
                     /translation="MRIENLKMKCLYKKHRFSGKEDFSDMIDVITSQGGIDKIKIIPE
                     YGDINDNTIKFLKAIGFDINTLNIEVGTIESGIALIKNGYNLYKTGSAWIPSIAKCEL
                     PVINEALNRGLDITKFSYKNHFDTHEAYNEFDDEYYTVTNPFSHFLKNHNNGMDGVFS
                     KFDFICEDRLKLFLDKNILNKDTLKEFEREGHPLYYYYPCNKGFEDKNIERLMNLYQK
                     VEINEGKIFEHHRQAVRNHIFKRQIELSENPVQTCKDIVELHNKWRIDIKSSDEILKP
                     LIESVLNSKPVEPQTPQRVKFTRRRM"
     gene            complement(3816..4724)
                     /locus_tag="IT892_004186"
     CDS             complement(3816..4724)
                     /locus_tag="IT892_004186"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137318.1"
                     /translation="MIITINDNEYNKLYEAGNLDREAIIDTIVKAGGTDKVRVSVCYN
                     GQNPLDITINEEEKETLDTLSFLKGIFEDINNVIIEHTPSDTICIALIKWGYDMTQLD
                     DFGIPHIANFGKEALLEVIKNGLDMSQFTQGDHFDFNHNHRFSRFINTNEKLEVFLQS
                     GLLAPDTIKDYECFEHHKLYNKPDLNLTDKGFELLLKCYDSISLNTEMMSSYSIFSGK
                     TTNNPAVFKLTDNDKHLDHLFKRYIEVSPDKIEAVNFIKGLFQKSESHDLNSGNYPNT
                     VTTIEDIEIQNVFKQSQPKAITRRRM"
     gene            complement(4733..5605)
                     /locus_tag="IT892_004187"
     CDS             complement(4733..5605)
                     /locus_tag="IT892_004187"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137319.1"
                     /translation="MTSISDKNKKLLYKKLTGINQDGIIDAIVRAGGVDNINIFNDLN
                     LFTHIESIEGIKFLKTIGYDISNINIFTCSPDIGVELIKQGYDMYKLRQNNKPVIADC
                     DLKVIKECINQGLDMSKFSKENHFSLYSENFLLTNEISHFLESFQNVNFIDEKKLELF
                     IDSGVFNSKNASDFDGYVPLYYFCDSRYGGKLSDELLDKLINVYDKIDIIEERIFDPD
                     NERAKDFIFKRYIETSEDKQGAIEHVKGLFEKEGLDIEQSERIMATIARYDNAAIKEV
                     FTHTAPKPSTRRRM"
     gene            complement(5616..5801)
                     /locus_tag="IT892_004188"
     CDS             complement(5616..5801)
                     /locus_tag="IT892_004188"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137320.1"
                     /translation="MIIKAEEMEKVMYGERLKEFIPEKKKPKLLADIYHAENLFRRNS
                     IDKIDTSNKIELAVNKR"
     gene            complement(5823..6326)
                     /locus_tag="IT892_004189"
     CDS             complement(5823..6326)
                     /locus_tag="IT892_004189"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137321.1"
                     /translation="MDDMIIRSVKSALKHSKRKGTTAMDFLLTDSHTQLKLDDRYGGI
                     ADTGHMFAILVEDHYKKKFKDITRKGNVVTIKVARDILVGFRFSYSPGSLSVYYKIRV
                     KGKNYKEGIKVIDGFNRTSESIINNIINKARQQIVSIKFIAGMTVLAISGVGMFYAIF
                     NLNTLIT"
     gene            complement(6341..6934)
                     /locus_tag="IT892_004190"
     CDS             complement(6341..6934)
                     /locus_tag="IT892_004190"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137322.1"
                     /translation="MAKFNLIGKNPEQAKKYLTFWTIVNAGEEERYQEAMQLSLEPGF
                     TINKTKTNGMFFMEDMMISCRKEFFSLFMDTHRQTVKYHLSRRSYTIPELVISRYMGS
                     YTRLASDEERIDHLTTNIVCFLDAMLATGTHKRLQHLDSYEKLIAKVEEYYMGVIADL
                     PSVRLYEALKAKAAGNEQAELKEVIAATTGTTKKRRL"
     gene            complement(6921..7457)
                     /locus_tag="IT892_004191"
     CDS             complement(6921..7457)
                     /locus_tag="IT892_004191"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137323.1"
                     /translation="MILKERDLVGFKLILNQNRISSSLVNYKLCIVEADKEIKRIVSS
                     NTFIYEEVTCKQYRNKKTGEYKLSVDAQENLDRMLSVFTNTREICKIMIQYFISQTNR
                     TDSIKEELKSVSIEITDKVFNKVKADDQTLILITHHEVMKQLIKMDWWKDNEAKRMEI
                     LKEIEMRKEQLGGVYGEI"
     gene            complement(7454..7807)
                     /locus_tag="IT892_004192"
     CDS             complement(7454..7807)
                     /locus_tag="IT892_004192"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137324.1"
                     /translation="MFIVVLFNLFKNTFLTKYKRLDESGFWKNIFHLLKWLKGKINYL
                     VGVYFFSMTLLFSIMVFVFRDKTFTLDITAYILCAFISVGLSVLFYTYRDINFDIKTY
                     KQVRQEQKEERRRKV"
BASE COUNT         2170 a         1537 c         1180 g         2950 t
ORIGIN      
        1 aataagctgg ggcaataaat ttattatctt cattgtttat tcataattat attagctgga
       61 ttgttcttta atttgctttt caagttttct taattttctg gataacataa tggtatgtgc
      121 tgctgtcatt accacacaaa aaatcattga ataaattagt gatcctgcaa ttaatagtgt
      181 tgtatcgctc atagtaagct ccttagttgg ttatttatcg taaaagtaaa ctgtaacggg
      241 tctgttatca gaaaccgagg cacaggcttg tgctgccgtt tctacattaa aatctttatt
      301 gtctgctgtg ttcttcactt ctgttccttc cacctgaatc ttaaagaagc tggctcctgc
      361 ctgggatatg aacttaggac aagcatcagg agatatgttt tcaaacccga tacggtagga
      421 accgtcatac caggcatcta tcagaacggt agcaccccag gcattccaga tctgaccgtc
      481 ttcaacattg tcctccggga cgagctgggc ttttatgacc atatccgtag ataagccgtc
      541 atagttcgcc ttactcgcaa atatgctctt aataccgccg ttaatggtgg agagaagctt
      601 catatcgctg tctatcttct gacttgaact taccttcggg taaatcatga aaacacctat
      661 ggcgagaaca gcggccaccg ccagaaccag catcatttca agaagggaga aagcttttgt
      721 tcgtgtgtgt agtctcatag ccagccccct taaatgattg aagaaaacat aatggttgaa
      781 acggtatcag aaccacatgc actggctgtt ttggcgacat ctaagggctt cccttcttcg
      841 tcgttcttca catcgccacc gctaccgccg ttgtatatgg ttatgctcac gaagttgcca
      901 gaaacaccgg taatgaactt agaacaggct tccgctggaa caccgttgta agtgatcgag
      961 tatttgccgt ggttaccctg gtaggctatg tctacttccc ctttccactc attgataagc
     1021 ttgccgtcct gcaccatgtt gtcaggaaca ttctttgact gaatcagaac ggtcgggctt
     1081 aacccggaga gcctggatct acccgcatac agggctttca ctcccgcctg taaggtggtt
     1141 atgttcttac tttctttctc tatcttctga gaagctacca gcttcggata aagcacaaat
     1201 gcaccgatta ccagagccgc agccacggca agaacaagta atatttctaa aaggctaaaa
     1261 cctttatttt gtatttttat taatttcata gtcattcccc tttgttgatt tatatttttc
     1321 ttctaatttt ctatattctc ttttgtaggt atcacatgaa gtatcagaat ccaaatgaaa
     1381 ggaataaata cccggttgta attcaccttc cattttgcag acctgaattt tcatatctaa
     1441 taactccata actttctttt cactttctct attttttgac tctgctaaat ttatcgaatt
     1501 ttcattgctt gcattaataa tttttgaatt aataactggt attgcaaata tcataaaaaa
     1561 cataaataat atcgctattg tcgataaaat ttcttcttgc tgatttgcat gatttatctt
     1621 ttgttctaat tgcttgcaat ttttgcattt gtattttctt ttctttgcca taatcatcac
     1681 cccttaaagt ctttttcttt ttattgttgg taaagaattg gctctatcat tagatatgat
     1741 tttaagaaga agcttgtttt gttcgttaac cgataaaaga cttaatttac ctttgaagcc
     1801 aaactcattt aaaagaaact ttctttcttc actgtcattg tattcaatta accaactgga
     1861 ctcttccata tcttccatag tataaaagta tgttgccatc ggatgattaa agctaaacag
     1921 gctattaatg tcaggcaatc cttctttaag aattgattct ttcaccattc tttctttgct
     1981 gcacacagat aaatttttaa ttttattttt cataaatcac cccgttattt atatttgtta
     2041 ttcctaccct cttatatatg tataaatgcc ccagtgaaat tgtcaataag ctggggtaaa
     2101 ataaaataat tgaaagtatt agtggttcac ctgattatat aaacggtaga tttatatctg
     2161 tttataaaag ttagtcttaa tggaaaatat cacatcatca acactatcac tcttgataaa
     2221 agttcctgcc atataaacgg catacagata gttatcgtaa atatcatatt tgttgttggt
     2281 tgctgcatat cttacacact ggttaactgt ttcctttttt acaccagtat attttttatc
     2341 gaatacagtt aagttcattg tttctatgaa catgcgatct ggctgtaatt gctgcataca
     2401 gttttcaaag ttcattaacc acagcccatt ttgttctgag cttactctgt tcctgttctt
     2461 gtctgctgca cagaaatcat taacggctga atccacgaca acaccgttaa tctgtaccgg
     2521 tgaaaggtat tgtttcctgt ttatgctgtt gctcctgttc catgacatac agttttcgta
     2581 atcctggtta acctgtggga tcactgtttg ctgttccttc ggttttaaca agctgtatgc
     2641 tgtcagaacg gcaagaacgg cgataccaca gtaaaagcct ttcctgttgc taactatgct
     2701 gttcctgatt ttcctttctg tattcagata ggttttcttc aattcttttt tttgtttttt
     2761 agataaaatg ttttccatag taattacccc tcttatagtt atttttttta tacatctaat
     2821 aggtacagtg aaattgtcaa taagctgggg caaaaaaaaa gacaactggt taagctgtct
     2881 tttatgtgag tagtttcatt acattcttct tctggtgaat ttcactcgtt gcggtgtttg
     2941 tggttctacg ggcttagaat ttaaaacact ctcaataagt ggtttaagaa tttcgtcgct
     3001 tgattttata tctatcctcc acttattatg tagttcaact atatccttac aagtttgaac
     3061 tggattttcg ctgagttcaa tctgtcgttt gaatatatga tttcttactg cttgcctgtg
     3121 gtgttcaaaa atcttacctt cgtttatctc caccttttga taaagattca ttaatcgctc
     3181 aatgttttta tcttcgaatc ccttattaca tgggtaatag taataaagtg ggtgtccttc
     3241 tctttcaaac tctttcaaag tatccttgtt taaaatattt ttatcgagaa atagttttaa
     3301 cctgtcttca catataaaat caaatttaga aaacaccccg tccataccat tattgtgatt
     3361 tttaaggaag tgtgaaaaag gattggttac cgtataatat tcatcatcaa attcgttgta
     3421 agcttcatga gtgtcaaaat gatttttata agagaatttt gttatgtcta accctcggtt
     3481 taatgcttca ttgattacag gaagttcaca cttagcaatg gatggtatcc atgccgaacc
     3541 agttttatat agattatacc cgttttttat taaagctatt ccagattcaa tcgttcctac
     3601 ttcaatgttt aaagtattaa tgtcaaatcc tattgcttta agaaacttta tagtattatc
     3661 gtttatgtct ccgtactcag ggataatctt tattttatct atgcctcctt gacttgtaat
     3721 aacatcaatc atatctgaaa agtcttcttt cccagaaaat ctgtgtttct tatataaaca
     3781 tttcattttt aaattttcta ttctcataaa tcctcctaca ttcttcttct ggtaatggct
     3841 tttggttgtg attgtttgaa tacattctgt atttcaatat cttctattgt cgtaactgta
     3901 ttaggatagt tcccactgtt caaatcgtga gattctgatt tctggaaaag gccttttatg
     3961 aagttaacag cttcaatttt atctggactc acttctatat atcgtttaaa caaatggtct
     4021 aaatgtttat cattgtctgt taatttaaat actgccgggt tatttgtggt tttacctgaa
     4081 aatatactat aagaactcat catttcggtg tttaatgata tggagtcata gcattttaaa
     4141 agcaattcaa accccttatc agttagattt aaatcaggtt tattataaag tttgtgatgt
     4201 tcaaaacatt catagtcttt tatagtatca ggtgctaata atccagactg aagaaagact
     4261 tcaagttttt catttgtatt tataaaacga gagaatctat gattatgatt aaaatcaaaa
     4321 tgatcacctt gtgtaaattg actcatatct aacccgttct ttatcacttc taatagtgct
     4381 tccttaccga agttagcaat atggggtatg ccaaaatcat caagctgtgt catatcatag
     4441 ccccatttta taagagctat acagattgtg tcgctcggtg tatgttctat aataacattg
     4501 tttatatctt caaatattcc ttttaaaaac gataatgtat ctaatgtttc tttctcttcc
     4561 tcatttatgg ttatatccaa tggattctgt ccgttgtaac aaacactaac tctgacttta
     4621 tcggtacccc ctgccttaac tattgtatca ataatagctt ctctatctaa attcccagcc
     4681 tcatatagct tgttatactc gttatcattt atagttataa tcatagttcc tcctacattc
     4741 ttcttctggt gctgggtttt ggtgcggtgt gtgtgaaaac ttccttaatt gctgcattgt
     4801 catatctggc tatcgttgcc ataatccttt cactttgttc aatatctaat ccttcctttt
     4861 caaaaagccc cttaacatgc tcaattgcac cctgtttatc ctcgctggtt tcaatgtatc
     4921 ttttgaagat aaaatccttt gctctttcat tatcaggatc aaatattcgt tcttctatta
     4981 tatcaatttt gtcgtaaaca ttaattagct tatcaagtaa ttcatcacta agttttcctc
     5041 catagcgtga atcgcagaaa taatataatg gaacataccc atcaaaatca ctcgcatttt
     5101 tactattaaa aactccgcta tcaataaata actcaagctt cttttcgtca atgaaattta
     5161 cattttggaa gctttcaaga aaatgcgata tttcatttgt tagcagaaag ttttcactat
     5221 ataaactaaa atggttttcc ttgctaaatt tactcatatc taacccttga ttaatacact
     5281 ctttgatgac ttttaaatca cagtctgcga tcacaggttt gttattttgt cgtaatttat
     5341 acatgtcgta tccttgtttg attaactcaa caccgatgtc tggactacat gtaaaaatat
     5401 tgatattgct aatgtcataa cctatggttt ttaaaaattt tattccttct atactttcta
     5461 tatgagtaaa taaatttaag tcattaaaaa tattgatatt gtctacacct cctgctcgaa
     5521 ctattgcatc tataatgcca tcttgattta ttccagttag ttttttatat aataactttt
     5581 tatttttgtc ggatatgctc gtcataatta actccttatc ttttgttgac tgctaattct
     5641 attttatttg atgtgtctat tttgtctata ctgtttcttc taaaaagatt ttcagcatga
     5701 taaatgtctg cgagtagttt aggttttttc ttttctggaa taaattcttt caacctctcg
     5761 ccatacatta ccttttccat ttcttccgct tttattatca taagtcaccg ccttttttat
     5821 aattatgtga ttagtgtatt taaattaaat attgcataaa acattcccac accagatatg
     5881 gctaaaacag tcataccagc aataaatttt attgaaacga tttgctgtct tgctttgtta
     5941 atgatgttgt ttattatgct ttctgatgtt ctgttaaacc catcaattac ctttattccc
     6001 tccttataat ttttcccttt aaccctgatt ttgtagtaaa cggatagaga gcctggcgag
     6061 tagctgaatc tgaaccctac cagtatgtct cttgctacct taatggttac tacattcccc
     6121 tttcttgtta tgtctttaaa cttcttcttg tagtgatctt ccaccaggat agcgaacata
     6181 tgccctgtat cagctatccc cccgtatctg tcgtccagct tcaactgtgt gtggctatcg
     6241 gttaacagga agtccatagc tgtcgttccc tttcttttgc tgtgcttcaa agctgattta
     6301 acagacctga ttatcatatc gtccataccc tttcccccgt ttacagtctt ctcttcttcg
     6361 tcgttcctgt cgtcgctgct atgacttcct tcagctccgc ttgctcatta cctgccgctt
     6421 tcgctttaag cgcctcatag agccttacag acggcaaatc ggctataacc cccatgtaat
     6481 actcttccac cttcgctata agcttctcgt agctgtccag gtgctgtaat cgcttatgtg
     6541 tgccggtggc caacatggca tcgagaaaac agacaatgtt tgttgttaag tggtctatcc
     6601 tttcttcatc acttgcaagc ctggtataac tacccatgta tcttgaaatg accagttccg
     6661 ggatagtgta agatctgcgg gataagtggt atttgaccgt ttgacggtgt gtgtccatga
     6721 acagagagaa gaactcttta cggcaagaaa tcatcatgtc ttccatgaaa aacatgccat
     6781 tggtttttgt cttgtttata gtgaatcctg gttcaagaga taactgcata gcttcctgat
     6841 atctttcttc ttcccctgca ttaacgattg tccagaaagt aagatatttt ttcgcttgtt
     6901 cgggattttt accaatgaga ttaaatttcg ccataaacac cccctaactg ttcttttctc
     6961 atttctattt ctttaagaat ttccattctt ttagcttcat tatctttcca ccaatccatt
     7021 ttgattaact gcttcataac ttcatggtga gtgataagta ttaaagtctg atcgtcagct
     7081 ttaaccttat taaaaacctt atcagtgatt tcaatcgaaa cggattttaa ttcttctttt
     7141 atgctgtcag ttctgtttgt ctgacttata aaatactgaa tcattatttt gcaaatttcc
     7201 ctggtgtttg taaatacaga taacattctg tccagatttt cctgtgcatc tacacttaac
     7261 ttgtactcac ccgtcttttt attgcgatac tgtttacaag tcacctcttc atatataaaa
     7321 gtattacttg atacgattct ttttatctcc ttatcagctt ccacaatgca aagcttatag
     7381 ttaacaaggc ttgatgatat tctgttctga ttgagaatga gtttaaaacc cactaaatct
     7441 ctttctttta agatcatact tttctccttc tttcttcttt ttgctcttgt cttacttgct
     7501 tgtaagtttt aatatcgaaa tttatatctc tgtatgtata aaacaaaaca cttaaaccaa
     7561 cactgataaa ggcacataga atatatgcag ttatatctaa cgtgaatgtt ttatctctga
     7621 atacaaacac cattattgaa aacagtaatg tcatactgaa aaaataaacc ccaacaagat
     7681 aatttatctt ccctttaagc cacttcaata aatggaatat atttttccag aatccagact
     7741 catcgagtct tttgtattta gttaaaaagg tgtttttgaa taaattaaaa agaacaacaa
     7801 taaacataaa ccccatgata attgttattg gaatagt
//
LOCUS       DACAOP010000152         7710 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.152, whole genome shotgun sequence.
ACCESSION   DACAOP010000152 DACAOP010000000
VERSION     DACAOP010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7710
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.152"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(19..171)
                     /locus_tag="IT892_004193"
     CDS             complement(19..171)
                     /locus_tag="IT892_004193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HAP3137325.1"
                     /translation="MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVL
                     AYESKK"
     gene            complement(436..1170)
                     /gene="cysH"
                     /locus_tag="IT892_004194"
     CDS             complement(436..1170)
                     /gene="cysH"
                     /locus_tag="IT892_004194"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HAP3137326.1"
                     /translation="MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNL
                     PGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLK
                     VYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQ
                     SGSRTNLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTT
                     RKWEPGMAEEETRFFGLKRECGLHEG"
     gene            complement(1244..2956)
                     /gene="cysI"
                     /locus_tag="IT892_004195"
     CDS             complement(1244..2956)
                     /gene="cysI"
                     /locus_tag="IT892_004195"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HAP3137327.1"
                     /translation="MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGF
                     KGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKF
                     AGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
                     PYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKT
                     TVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGY
                     LPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPI
                     RPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRI
                     TANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERF
                     LPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGN
                     RIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPAR
                     DLWD"
     gene            complement(2956..4755)
                     /gene="cysJ"
                     /locus_tag="IT892_004196"
     CDS             complement(2956..4755)
                     /gene="cysJ"
                     /locus_tag="IT892_004196"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /protein_id="HAP3137328.1"
                     /translation="MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVL
                     NQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYK
                     FKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEF
                     FCQSGKDFDSKLAELGGERLLDRVDADVEYQAAAIEWRARVVDALKSRAPVAAPSQSV
                     ATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDAL
                     GVWYQNDPALVKELVELLWLKGDEPVNVEGKTLPLNEALQWHFELTVNTANIVENYAT
                     LTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIAS
                     SQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPAN
                     PETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKE
                     GVLTRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQAL
                     LEVIAEFGGMDTEAADEFLSELRVERRYQRDVY"
     gene            5071..5436
                     /gene="queD"
                     /locus_tag="IT892_004197"
     CDS             5071..5436
                     /gene="queD"
                     /locus_tag="IT892_004197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HAP3137329.1"
                     /translation="MMSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGE
                     VDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPL
                     LSAVMVKETCTAGCIYRGE"
     gene            5514..6785
                     /locus_tag="IT892_004198"
     CDS             5514..6785
                     /locus_tag="IT892_004198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417246.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP3137330.1"
                     /translation="MEDNCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNL
                     SGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRA
                     RFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
                     AERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGA
                     FLYTNQQTLSLGIVCPLSSLTQSRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVP
                     EGGLHSMPVQYAGNGWLLLGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHRE
                     PQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKP
                     VPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL"
     gene            6776..7036
                     /locus_tag="IT892_004199"
     CDS             6776..7036
                     /locus_tag="IT892_004199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311649.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HAP3137331.1"
                     /translation="MSVARNLWRVADAPHIVPADSVERQTVQRLINACPAGLFSLTPE
                     GDLRVDYRGCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG"
     gene            7053..7628
                     /locus_tag="IT892_004200"
     CDS             7053..7628
                     /locus_tag="IT892_004200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate responsive antiterminator"
                     /protein_id="HAP3137332.1"
                     /translation="MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTIS
                     NIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGF
                     FCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVC
                     DEEDARNAINAGVVALSTTNTGVWTLAKKLL"
BASE COUNT         1682 a         2076 c         2033 g         1919 t
ORIGIN      
        1 tttacccccg cgtggtggct acttcttcga ttcgtaagcg agaactgcct taaactccat
       61 accacgttct ctgatactca actcacacaa cgagtcgcct accatcagcg tgaatcccag
      121 tactgtacaa cacagtacga tgattgccac aagggcatat tttgtcagca tgtcttgcct
      181 ccctgcaaag aagagactaa cattcgaatt gcttaggttc gaacgctggc ctcaggttga
      241 tagaaatatc gcctggggct tttgtccatc tggaacctcg cgaatgctta acgccagaca
      301 gcctcaagca cccaacgcca ttctatacct gataattctt ccagcggcgt tcacgtttaa
      361 aatcaggaat gctgctcgca aaataaaaac gcccccatca tttctgacag aggcgtttaa
      421 tttatccggc aatatttacc cttcgtgtaa cccacattct ctttttaagc caaagaaacg
      481 cgtttcttct tccgccatgc cgggttccca tttacgggtt gtatgggtat caccgaccga
      541 taaatatcct tcatcccata atgggtgata tttcaggcca tgtttttgca ggtactgata
      601 aatagttcgg ttatcccagt cgataatcgg cagcacttta aatacgccac gctgaattgc
      661 cagcaccggt aaattggtgc ggctgccgga ttgttcacgg cgcaggccag caaaccaggt
      721 ttgcgcattc agttctttca gcgcccggtt catcggttcg actttgttga tgtcattgta
      781 cttttcaatg ccttcaacac cctgctccca cagttttccg taacgtgctt cctgccaggc
      841 ggcgctttcg gtagcgcggt acactttcag gttgagcttg agtttgtccg ttaactcgtc
      901 aataaagcgg taggtttccg ggaacaagta acccgtatcg gtgaggatca ctggaatatc
      961 cgggcgaatc tgattcacca gatgcaggct caccgccgcc tgaatgccga aactggaaga
     1021 aagtacatat tcaccgggca gattatccag cgcccaggca acgcggcctt cagcgtccag
     1081 tttttccagt tcggcgttag tttctgccag cgccagaatg cgatctacct tcggcagttc
     1141 gttcagggcg tttagatcga gtttggacat agattcctca ctgtttgcct tgcctgatgc
     1201 gacgctcacg cgtcttatca ggcctacaag accgggctga tggttaatcc cacaaatcgc
     1261 gcgccggatc gagcaccggg cgaatgatgc ccgcacgcac cgtaaagtcg ccgaagcctt
     1321 cacccgcttc gcgctctttc gcccagcgcc ctatcagttc atcaagcgac gccaggattt
     1381 ccggttcggt gatgttttct ttatacatcc gtgggatacg tgtcccaatg cggttgccgc
     1441 caagatgcag gttgtagcga cccggcgctt tacccaccag gcccacttcc gccagcatcg
     1501 cgcgaccaca accgttcggg cagcctgtta cacgcatcac gatatgctca tcgctgacac
     1561 catgtttcgc cattaaatta tcgatgttgt cgataaaaga cggcaggaaa cgctcggctt
     1621 cggccatcgc cagcgggcaa gtcgggaatg acacgcaggc cattgagttt tcacgctgcg
     1681 gcgtgacggc attcattaac ccgctctctt tggcaatctt ctcgatcttc gctttctcgc
     1741 tttccggcac accggcgatg atcagattct ggttcgccgt aatgcggaaa tcgcctttgt
     1801 ggatcttcgc gatctccagc aggccggttt tcagcggacg cccaggataa tcaaggatgc
     1861 gaccattttc gataaacagc gtcaggtgcc agttatcatc aatgccttta acccagccaa
     1921 tacgatcgcc gcgtccggtg aactcatatg gacggatcgg ttcaaatttg atccccgcgc
     1981 gacgctccac ttccgcttta aacgtctcaa cccccacgcg ctccagcgtg tatttggttt
     2041 tggcattttt acgatcggta cggttacccc agtcgcgctg agtcgtcacg acggcttctg
     2101 ccaccgccag cgtatgctcc agcggcagat agccaaactc actcgccgtg cgggcgtagg
     2161 ttttcttgtt gccgtgttcg atagaaagcc caccgcccac caacaggtta aagcccacca
     2221 gcttgccgtt ttcggcgatt gccacgaagt tcatgtcgtt ggcatgcaga tcgatatcgt
     2281 tctgcggcgg gatcactacc gtagttttga atttacgcgg caaataagtc tgaccgagga
     2341 tcggttcttc atcggtggtg gcgacttttt cctgatcgag ccagatctcc gcatacgcgc
     2401 gggtacgcgg cagcagatgt tcagagattt tcttcgccca ttcatacgct tccgcgtgta
     2461 gctgcgactc gtaagggttc gaggtgcaga gtacgttacg gttcatgtcg ttagcagtcg
     2521 ccagcgcatc aagaccgacc gagtgcagca tctggtgcac cggtttgacg ttctttttca
     2581 gaatgccgtg gaactgaaac gtctggcggt tggtcaggcg aatgctgcca tagatggtgt
     2641 tttcaccggc aaatttatcg atcgcctgcc actgtttggt ggtaatcacg ccacccggca
     2701 gacggcagcg caacagcatt gcatgacgtg gctccagctt ctgttcagca cgttcggcgc
     2761 ggatgtcgcg gtcatcctgc tgatacatgc cgtggaagcg gatcagcagg aagttatcgc
     2821 ccttaaagcc gccggtcaga ccgtcgttta aatcttccgc aatggtgccg cgcaggtagt
     2881 tgctttcaag cttcatgcgc tcggcgtctg tcagttttcc ttcgaccact aaaggccctg
     2941 gatgtttttc gctcattagt agacatctcg ctgataacgg cgctctacgc gcagctcact
     3001 taaaaattca tccgccgctt cggtgtccat gccaccaaat tcggcaatca cttccagaag
     3061 tgcctgctca acgtctttcg ccatgcgatt agcgtcgccg cagacataaa tgtgggcacc
     3121 gtcattgatc cagcgccaca gctctgcgcc ctgttcgcgc agtttgtctt gtacgtaaat
     3181 tttttctttt tgatcgcgcg accaggcaag atcgatacgc gtcagcacgc cctctttgac
     3241 gtagcgctgc cattccacct ggtagaggaa atcttccgta aagtgcgggt tgccaaagaa
     3301 cagccagttt ttccccggcg cttcgtcggc ggcgcgttgc tgcataaagg cgcggaacgg
     3361 cgcgatgccg gtgcctgggc caatcataat caccggcgtt tccggattgg ctggcaggcg
     3421 gaagttatcg ttatgttcga taaagacgcg gacttcaccc tcttcttcca cgcgatccgc
     3481 gaggaagctg gaggcaccac cggcacgggc gcggccttcc acgtcgtaac gcaccacgcc
     3541 aacggtgacg tgtacttcgt tctcgacttc cgcctgcgag gaggcgatgg aatacaggcg
     3601 cggggtcagc gggcgcagca ggttaatcag cgcttcggca tccagttgcg ccggagagaa
     3661 acgcaccatg tcgacaatcg gcgtcgtcgc ggcgtaatgc tgtaacttcg ctttatcgcc
     3721 caccagcggc agcagcgttt cgctgcgggt aagcgtggca tagttctcaa caatgttggc
     3781 ggtgttgacg gtcagttcga agtgccactg tagcgcttcg ttcagcggca gggttttgcc
     3841 ctcaacgttg acaggttcat cacctttcag ccacagcagt tcgacaagtt ctttcaccag
     3901 tgccggatcg ttctgatacc agacgcccag cgcgtcaccc ggctggtaac gcaggcccga
     3961 gtcacctaag tcaatttcga tatggcgaac gtctttttca gagttacgcc cggtaatttt
     4021 ctggttaaca gagaggctcg ccaccagcgg cgcgtctttg ctgtacgggc tggtgtggat
     4081 ttcatttacc gcgccagtag cgacggattg cgaaggtgcc gcgacaggcg cacgcgattt
     4141 aagcgcatca accacgcggg cgcgccactc gatggcagca gcctggtatt caacgtcggc
     4201 atcgacacgg tcgagcaggc gttcaccgcc cagttccgcc agcttgctgt caaaatcttt
     4261 cccggactgg cagaaaaatt cataagagct atcgccgagg ctaaacacgg caaatgcggt
     4321 gttttccagc ttcggcgctt ttttggagaa caggaactta tgcagcgcga cggcttcttc
     4381 cggcggttcc ccttctcctt gcgttgacgt caccacgata agcagttttt cgctggcgat
     4441 ttgtttgaat ttatagtcgc ccgcgttcac cagcttaacg ttcagttttg ccgccaataa
     4501 atcatcgcgt aatgcttcag caacccggcg cgcattgccg gtttgcgaag cggagataat
     4561 agttataccc ggcatttctg cggcgggcgc tggcgtcgct gcaagcgcag ctggctgctg
     4621 gttgagcacg ccccagaaat agccagaaac ccaggcaagc tgggtgggag ttaaatcggt
     4681 cgtggccgcc tgaaggcgtg ccagttgctc cgggttcaac ggaagcaacg cggaaggtgg
     4741 gacctgtgtc gtcatgcgtc gttatgttcc agtaagcaaa gctgtttctg cgccctgtca
     4801 gcgcccataa aacagaagag aagataaggt taacggggtg aacggtgtgg attaaagacg
     4861 ggatagcgat aactaataac caaatcgact aacctgtttt agcaatagtc tttaacaaca
     4921 aaatagatta accaacccaa tgaaaaacaa atgaatattg cccatcaata agataaatca
     4981 gcgattttgc gcaacaaagt cgttttagat aatgcgaaaa aacagccttt ccggtactct
     5041 acggcggttt tatcgtcctg tagagaaatt atgatgtcca ccacgttatt taaagatttc
     5101 accttcgaag ccgctcaccg cttaccacac gtcccggaag ggcataaatg tggtcgcctg
     5161 cacgggcatt cctttatggt gcgactggaa attaccgggg aagtcgatcc gcatacgggc
     5221 tggattatcg atttcgctga actgaaagcg gcgtttaagc caacctacga gcgcctcgat
     5281 caccattatc tcaatgatat tccaggtctg gaaaacccaa ccagcgaagt tttagcaaaa
     5341 tggatttggg atcaggttaa acccgttgtg ccgctgttaa gtgcggtgat ggtaaaagaa
     5401 acctgtactg caggctgtat ctatcgcggc gaatgataag agtgtgtcgg cggtcaattt
     5461 cccttaagta acgccatgtt agggtgttgt gttctggata tctggggcat gacatggaag
     5521 acaactgcga cattattatt attggtgccg gtatagcagg taccgcttgt gctttacgct
     5581 gcgcgcgggc aggtttgtcc gttctgttac tggaacgcgc tgaaatcccc ggcagcaaaa
     5641 atctttccgg cgggcgttta tacacccatg cgctcgcgga actcctcccg caatttcatc
     5701 tgaccgcgcc tcttgaacga cgcatcactc acgaaagcct ttctctgcta acgccggatg
     5761 gcgcaacgac gttttccagc ttacagcccg gcggtgaatc ctggagtgta ttacgtgcac
     5821 ggttcgatcc gtggctggtt gccgaagccg aaaaagaagg tgtcgaatgc atccccggtg
     5881 cgacggtgga tgcgctgtat gaagaaaacg gcagggtgtg tggtgtcatt tgtggtgacg
     5941 atattctccg cgcccgttat gtggtgctgg cagaaggtgc caacagcgtc ctggctgaac
     6001 gtcacgggtt agtgactcgt cctgctggcg aagcgatggc gttggggatc aaagaagtgc
     6061 tgtcgctgga aacatccgct attgaagaac gttttcatct ggagaataac gaaggcgcag
     6121 cgttgctgtt cagcggcggg atctgtgatg acttacccgg cggcgcattt ctttatacta
     6181 atcaacaaac gctctcgtta gggattgttt gcccgctctc ttcccttacg caaagtcgtg
     6241 ttccggcaag cgagctgctg gctcgcttta aaacgcatcc ggcagtgcgc ccgcttatca
     6301 aaaacacgga atcactggag tatggtgcgc atctggtgcc agaaggtggc ttgcacagta
     6361 tgccggtgca atacgccggt aacggctggc tgctgctggg cgatgcgttg cgcagttgcg
     6421 tcaataccgg aatttccgtg cgcggcatgg atatggcgct aactggcgcg caggcggcgg
     6481 cacaaacgct gataagcgcc tgccagcacc gcgagccgca aaatctgttt ccgctttatc
     6541 atcacaacgt cgagcgcagc ctgctatggg atgttctaca acgttatcag catgttccgg
     6601 cgcttttgca acgccctggc tggtaccgtg cgtggcctgc gttaatgcag gatatttccc
     6661 gcgatttatg ggatcagggt gataaacctg ttccaccgct gcgccagtta ttctggcgtc
     6721 atttacgtcg tcacggcctg tggcatctgg cgggcgatgt tatcaggagt ctgcgatgtc
     6781 tgtagcccgt aatctctggc gcgttgccga tgcgccgcac attgttccgg ctgactccgt
     6841 tgagcgccag acggtacaac ggttgattaa cgcttgtccg gctggtcttt tttcgctcac
     6901 accggaaggt gacttacgcg ttgattatcg cggctgcctg gagtgtggca cctgccgttt
     6961 gctgtgcgac gaatcaacac tacaacagtg gcgctatccg ccttccggat tcggcatcac
     7021 ctaccgcttt ggataaataa taaggataat ttatgcccct cttacacctg ctccgccaga
     7081 atccggtgat tgctgccgtt aaagataatg ccagcctgca actggcaatc gattctgaat
     7141 gccagtttat ttcagtgttg tacggcaata tctgcaccat cagtaatatc gttaaaaaga
     7201 ttaaaaacgc cggaaaatat gcctttattc atgttgattt gctggaaggc gcatcgaaca
     7261 aagaagtggt gattcagttt ctgaaactgg tgaccgaggc ggacggcatt atcagcacga
     7321 aagcatcgat gctgaaagcg gcaagagcgg aaggtttttt ctgtattcat cgcctgttta
     7381 ttgttgattc gatttcgttt cacaacattg ataagcaagt tgcgcaatcg aatccggatt
     7441 gtattgagat cctgccaggc tgtatgccta aagtgctggg ctgggtgacg gagaaaatcc
     7501 gccaaccgct gattgccggc gggctggtgt gcgatgaaga agatgcgcgt aatgcgatta
     7561 acgcgggtgt tgtggcgctt tccaccacga ataccggggt ctggacgtta gcgaaaaaat
     7621 tgctttgacg ggatactcgt aacgagttga atttgtgtga tttgtaggct gcacgccaca
     7681 tccgacattc agcgcctgat gcgacgcttg
//
LOCUS       DACAOP010000153         7584 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.153, whole genome shotgun sequence.
ACCESSION   DACAOP010000153 DACAOP010000000
VERSION     DACAOP010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7584
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.153"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            201..1289
                     /locus_tag="IT892_004201"
     CDS             201..1289
                     /locus_tag="IT892_004201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAP3137333.1"
                     /translation="MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTE
                     ISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEIISATGSNSHRYINDN
                     HYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGIIPPDQFI
                     PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
                     VNKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
                     FPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
                     VHFLQGYLYSPPVPGNKFISEWVMKAGG"
     gene            complement(1331..2263)
                     /locus_tag="IT892_004202"
     CDS             complement(1331..2263)
                     /locus_tag="IT892_004202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3137334.1"
                     /translation="MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRME
                     TGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFYAIKRSIDTISQGIEARVRICIN
                     QLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGG
                     GIDYTEIGAIRWAFAIAPDHPLAFVPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLH
                     GQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMTQSLLVTRQIHNPRQDSRMLLAT
                     QHSATGQVTQWIKKQFAPNGILTGIYQDLLHREN"
     gene            complement(2355..2852)
                     /locus_tag="IT892_004203"
     CDS             complement(2355..2852)
                     /locus_tag="IT892_004203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HAP3137335.1"
                     /translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
                     FYAAGGGKSGFIRSLAVNYSGMVWAFFAALTAGWLASVSGLSAFWASVITTVPFSAVV
                     VWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGVISEYGGQKLSEATT
                     KRDGY"
     gene            3110..3715
                     /locus_tag="IT892_004204"
     CDS             3110..3715
                     /locus_tag="IT892_004204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HAP3137336.1"
                     /translation="MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
     gene            3755..4618
                     /locus_tag="IT892_004205"
     CDS             3755..4618
                     /locus_tag="IT892_004205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HAP3137337.1"
                     /translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFDDLFRHGDKVQFDDQGITVGQHLHIEMSRCRRWLSPTLQMTAV
                     NFHLIAWLQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNDKQNI
                     ASAVASMMGLGIGLTPSADDYLTGLALILFIPGHPAEKYKEEFYLGLQRGKNNTTLLS
                     AITLEAALQQRCRENIHRFIHNIIYDIPENATQAIEKIKHIGSSSGCDMLYGMADGCA
                     LSQTYGGNYVS"
     gene            4608..6155
                     /gene="fdrA"
                     /locus_tag="IT892_004206"
     CDS             4608..6155
                     /gene="fdrA"
                     /locus_tag="IT892_004206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HAP3137338.1"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKSGADNEQLLVEIEELFNTKAQSGSHEARYA
                     TIGSAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIALISKPPAPAVARKVLERARACRK
                     PVVVCFLDRGETPVDEQGLQFARGTKEAALKAVMLSGVKQENLDLHTLNQPLIADVRA
                     RLQPQQKYIRGLFCGGTLCDETMFAVMEKHGDVYSNIQPDPEFRLKDINRSIKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIETI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     gene            6155..7573
                     /locus_tag="IT892_004207"
     CDS             6155..7573
                     /locus_tag="IT892_004207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HAP3137339.1"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
                     QVVQALDNIADSPLADKIAAANQQALERIIQSHPVLIGFDQAINVVPGMTAKTILHAG
                     PPITWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPILRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
                     VASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGVGMIGAG
                     IVHPPFACFEKAILGWCERYGV"
BASE COUNT         1953 a         1841 c         2004 g         1786 t
ORIGIN      
        1 tttgacttgt gattaccttt ttaaggtatt tagcgtaact gtttttgagc gagcatcaga
       61 ggtaaagata atcttcttga tagtgatgtg ggatgttata cgtatggcat cgctgatgtt
      121 tatggttacc ccttatgtgt gctcaggaat cgacaggtaa tcactcatac tgaacagcga
      181 taaaagataa aggtgtgttc atgaattcat gtgattttcg tgtttttctg caagagttcg
      241 gtacaacggt tcatttgtca ttgcctggta gcgtatccga gaaagaacga ctgctactca
      301 agctgctgat gcagggaatg tctgtaacag aaatatcaca gtacagaaat cgcagtgcaa
      361 agacaatttc acatcaaaag aaacagctct ttgagaaact ggggattcag agcgatatta
      421 ctttctggcg cgatattttc tttcagtaca atccggagat catatccgcc acggggagta
      481 atagtcacag atatattaat gataatcact atcaccatat cgtcacgcct gaagccatca
      541 gtctggcgtt ggaaaaccac gaattcaaac cgtggatcca accggttttc tgcgcgcaga
      601 ctggggtact gacgggctgt gaggtgcttg tccgctggga acatccacaa acgggaatta
      661 tcccaccgga tcagtttatt cctctggcgg agtcatccgg tcttattgtc ataatgaccc
      721 gccaactgat gaaacagact gcggatattc tgatgccggt aaaacatttg ctgccggaca
      781 atttccatat tggcatcaac gtctcggcgg gttgtttttt ggcagcggga tttgaaaaag
      841 agtgtctgaa cctggttaat aaattaggta acgataaaat caagctggtt ctcgagctaa
      901 cggaacgtaa ccctattccg gtaacgccag aagccagagc gatatttgac agccttcatc
      961 agcacaacat tacctttgcg ctggatgact ttggtacggg ttatgcgacc tatcgttact
     1021 tgcaggcgtt cccggtcgat tttattaaga tcgataagtc atttgtgcaa atggcgagtg
     1081 tcgacgaaat ctccggtcat attgtggaca atattgtcga actagcgcgt aagcctggtc
     1141 tgagtatcgt ggcggaaggg gtagaaaccc aggagcaggc ggatttaatg atcggtaaag
     1201 gcgttcactt tttgcagggc tatttgtact ctccgccagt accgggtaat aaatttatct
     1261 ctgaatgggt aatgaaagca ggtggttgat gtaaaccgct attcacagcg catcgggagg
     1321 ttggcagcga ttaattctcc cgatgcagta aatcctgata gatccccgtt aatatgccat
     1381 ttggcgcaaa ttgtttttta atccactgcg tcacctgacc cgtagcagaa tgctgagtcg
     1441 ccagtaacat gcgcgaatcc tggcgcggat tatggatttg tcgggtaacc agcagggatt
     1501 gcgtcatcgc ctcacggacc atgtaatccg gcaaaaaacc aattccttca cctaaaatct
     1561 ggcactgaca tttggtgttg aaatctggca ccagaattga ctcctgcccg tgcagcaacc
     1621 agcccacttt tttattaatc gtatgcgcgg tgtcctccac cataatatta gggtagagac
     1681 gcagttggct ttcggcgatg ggttccggca caaaggctaa cgggtgatcc ggggcgatag
     1741 caaaagccca gcgaatcgcg ccaatttcag tgtaatcaat accgccgccg tccagtagtg
     1801 tatcgggtgc gccgatggcg atattggcct gattattaat aatcgcatcc cagacgccgt
     1861 tatacacttc ggtggtgacg gtaatctggc aggtaggaaa ctgctttttc agcacctgta
     1921 acaagcgtgc ggtgtgtttg ggcgtataaa gcagctgatt aatacaaatg cgcacacgcg
     1981 cttctatgcc ctgcgaaata gtatcgatac tgcgtttgat ggcataaaaa tcattcagca
     2041 ggtcggtagc tttgcggaaa aaataacgcc cggactccgt taactcaatg ctgcgggtac
     2101 tgcgagtgaa cagcaccaca tccagccccg tctccatacg cttaatggtg tagctaatgg
     2161 cggaagtggt taaacccaac tcttctgcgg ctttactgaa gctgccaaaa cgcgcagcgg
     2221 tagtaaatgc caacagattc tcttcggtaa aaattgagtt cattaaacca ttctcgccat
     2281 tatctactat gaatttctcc agctatgact gtagaggtat cggttaaaga tagataatca
     2341 tttttgaata acttttaata cccgtcgcgt ttagtcgtcg cttcgcttaa tttttgtcca
     2401 ccatattctg aaattacccc cacgcagtta cccgccagaa aacccagtaa cgtcaccgtc
     2461 cagttcatcc cgctggcaaa aaacagcgtc atgccgagaa agccaccggg aataaaggac
     2521 agtaaccaga aacgcccttg ccagaccact accgccgaga agggtacggt agtaattacg
     2581 ctcgcccaga acgcggacag tccacttaca gaggccagcc aaccagcagt cagcgcggcg
     2641 aaaaacgccc acaccatccc ggaataatta accgccagac ttctgataaa ccccgattta
     2701 ccgccgcctg cggcataaaa actgcaaaag gcgacgaagc caatggttcc taataattcc
     2761 catccttgag agagcccgac atgtgaagac actaactgcc aaagccctgc acaaataccg
     2821 acggtgacac ccgttgccgt gagtccgttc atcttgttcc cctctggtta gacatggacg
     2881 aaagctactc ttacatgtgc agactataga gaaataaaac ctgattgagt gaaagggtat
     2941 cgggtcaaag aaacaaatat tgcactaccg cacactgcga aaagattgtt gaatattatt
     3001 caacaaaaag gcgagatacg gcgaattaaa tttaagcggg ttcttttatc agattatcgt
     3061 tgctattctc aattcatcga aaacagccac aaaaaccagg ggaatgtgaa tgagtataaa
     3121 aaatctacct gccgactatt tattggctgc acaacagggt gatatcgata aagtaaaaac
     3181 ctgccttgcg ctgggtgtcg atattaatac ctgcgatcgt caggggaaaa cggcaattac
     3241 gctggcaagt ttatatcagc aatatgcttg cgttcaggca ttaattgatg ccggagcgga
     3301 tattaataag caagatcata cctgtttaaa tcctttttta attagctgtc tgaacgatga
     3361 tttaacgcta ctacgaatta ttttaccggc taaacccgat cttaattgcg taacccgttt
     3421 tggcggtgtc ggcctgacgc ctgcctgtga aaaaggccat ttaagtattg taaaagagct
     3481 tttggcgcat acggagatta acgttaacca gaccaaccat gtaggctgga cgccgctact
     3541 ggaagcgatt gtgcttaatg atggtggtat taaacagcag gcgattgtgc agttattgct
     3601 ggaacacggt gccagcccgc atctgaccga taaatatggc aaaacgccac tggaactggc
     3661 gcgggaacgg ggctttgaag agattgcgca gttactgatt gccgcaggtg cataaaccgg
     3721 gaggcttgct atcaacacac cagaaagacg gtgtgtgtgg gcgctaactg cggatgcgga
     3781 ttttctggcg cagcgggggc aaggacaggt tgaacaggtc tttgccagag cggtaaatat
     3841 cgcactcccg gctcgccagc agttgctgac gctgctttgt gaagagtacg acaatgcgcc
     3901 aaacagttgt cggttggcac tcactcactt tgatgatctg ttccggcatg gtgataaggt
     3961 tcagtttgac gatcaaggta ttacggttgg tcaacatctt catatagaga tgagtcgttg
     4021 tcggcgttgg ctgtccccaa ccttgcaaat gaccgctgtg aattttcacc ttatcgcctg
     4081 gctacagtgg cacgacatta ttcatcagca cctgggggaa aatgaaaccc tgtttaatta
     4141 tcgcggcgat aatccgtttt atcaggcgtt aaataaagaa ttacatatta aacgacgggc
     4201 agttattcag gccgtaaacg ataaacaaaa tatcgcctca gcggtcgcca gtatgatggg
     4261 gttagggatt ggccttacgc catcagccga cgattattta acaggtctgg cgcttatttt
     4321 atttattccc gggcatccgg cggaaaaata caaagaggaa ttttatctcg gtctgcaacg
     4381 cggcaaaaat aataccacat tattaagtgc cataacgctg gaagccgcat tacaacaacg
     4441 ctgccgggaa aatattcatc gttttattca caacattatt tatgacatcc ctgagaacgc
     4501 aactcaggca atagaaaaaa ttaaacatat tggctccagt tccggctgcg acatgctgta
     4561 tggcatggcc gatggttgtg cgctgagcca aacctacgga gggaattatg tcagttaaaa
     4621 tagtcattaa accgaatacc tattttgatt ctgtctcgct gatgtctatc tccacgcgtg
     4681 caaataaact cgacggcgtc gagcaggcat ttgtggcgat ggcgaccgaa atgaataaag
     4741 gcgtgctgaa gaatttagga ctgctgacgc cggagctgga gcaggcgaaa aacggcgacc
     4801 tgatgattgt catcaatggt aaatcgggtg cggacaacga gcagttactg gtggagattg
     4861 aagaactgtt caacaccaaa gcgcaaagcg gctcgcacga ggcgcgttac gccactattg
     4921 gcagcgccaa aaagcatatc ccggaaagta acctggcggt gatttcggtc aacggtctgt
     4981 ttgccgctcg cgaagcgcgt caggcgctgc aaaacgatct caacgtgatg ctgttttccg
     5041 ataacgtctc agttgaagat gaactggcgc tcaagcaact ggcccacgaa aaagggctgc
     5101 tgatgatggg gccagactgt ggcacggcga ttatcaacgg cgcggcgctc tgttttggta
     5161 acgccgtgcg tcgcggcaac atcggtattg ttggcgcatc cggcaccggc agtcaggagt
     5221 tgagcgtccg cattcatgaa tttggcggcg gcgtttcgca actgattggc accggcgggc
     5281 gcgacctgag cgagaaaatc ggcggcctga tgatgctcga cgccatcggg atgctggaaa
     5341 acgatccgca aactgaaatc attgcgctta tctccaaacc gcctgcgcct gcggtggccc
     5401 gcaaagtgct ggaacgtgcg cgcgcctgcc gcaagccggt ggtcgtctgc ttcctcgatc
     5461 gtggcgaaac gccagtggat gagcaggggc tacagtttgc ccgcggcacc aaagaggcag
     5521 cgctaaaagc ggtgatgctc tccggcgtga aacaggaaaa tctcgacctg catacgctta
     5581 accagccgtt gattgcggat gtgcgtgcgc gtctgcaacc gcagcagaaa tacattcgtg
     5641 gcctgttctg cggcggcacg ctgtgcgacg aaaccatgtt cgcggtgatg gaaaaacatg
     5701 gcgatgtcta cagcaacatt cagcccgatc cggaattccg cctgaaagat atcaaccgca
     5761 gcatcaaaca caccttcctc gactttggcg atgacgactt caccaacggc aagccgcacc
     5821 cgatgattga ccccaccaac cgcatcagtc gcttgatcga agaggcgcgc gatccagaag
     5881 tggcggtgat cgtgatggat tttgtgctcg gatttggatc gcatgaagat ccggtcggct
     5941 ccaccatcga gacgatcaaa gaagcgaaag cgatcgccgc tgccgaagga cgcgagttga
     6001 tcattctcgc ctatgtgctg ggtaccgatc ttgatacgcc atcgttagaa caacaaagcc
     6061 agatgctgct tgatgccgga gtgattctgg cgagcagcag caccaatacc ggattgctgg
     6121 cgcgtgaatt tatctgcaaa ggggaggaag cctgatgagc cagtcactgt ttagccaacc
     6181 attgaacgtt attaacgtcg gcatcgccat gtttagcgat gacctgaaaa agcagcatgt
     6241 agaagtgact caactcgact ggacgccgcc ggggcagggc aatatgcagg tggtgcaggc
     6301 gctggataac attgccgatt cgccgctggc ggacaaaatc gccgccgcta accagcaggc
     6361 gctggagcgt attatccagt cgcatccggt gctgattggt tttgatcagg cgattaacgt
     6421 ggtgccgggc atgacggcga aaaccattct tcacgccggg ccgccgatca cctgggaaaa
     6481 aatgtgcggc gcgatgaaag gcgcggtcac cggagcgctg gtgttcgaag gactggcgaa
     6541 agatctcgac gaggcggctg aactggcggc ttccggggag atcaccttct cgccgtgtca
     6601 cgagcacgac tgcgtgggat cgatggcggg tgttacctcg gcctcgatgt ttatgcacat
     6661 cgtaaaaaac aaaacctacg gcaacatcgc ttataccaac atgagcgagc agatggcgaa
     6721 gattttgcgt atgggcgcta acgaccagag cgtgattgac cgcctgaact ggatgcgtga
     6781 tgtgcaggga ccaatactgc gcgacgcgat gaaaattatc ggcgaaatcg atctgcgctt
     6841 aatgctggcg caggcgctgc atatgggcga tgagtgccat aaccgcaata acgccgggac
     6901 gacactgctg attcaggcgc tgacgccggg gattattcag gcgggttatt ccgtcgagca
     6961 acagcgcgaa gtgtttgagt ttgtcgccag cagcgactac ttctccggcc cgacgtggat
     7021 ggcgatgtgt aaagcggcga tggatgcggc gcatggcatc gaatacagca ccgtggtcac
     7081 caccatggcg cgtaacggcg tcgagttcgg cctgcgggtc agcggcctgc cggggcaatg
     7141 gtttaccggc ccggcgcagc aggtgatcgg cccgatgttt gccggttata agccggaaga
     7201 ttcggggctg gatatcggcg acagcgccat caccgaaacc tacggtattg gcggatttgc
     7261 tatggcgacc gcgcccgcta tcgtcgcgct ggtgggcggc acggtggaag aagctattga
     7321 tttctcccgt cagatgcgcg aaatcaccct cggtgaaaac cccaacgtca ccattccgct
     7381 gctcggtttt atgggcgtgc cgtcggcaat cgacatcacc cgcgtgggta gcagcggcat
     7441 tctgccggtg atcaacaccg ccatcgccca taaagatgcg ggcgtcggca tgattggcgc
     7501 gggcattgtg catccacctt ttgcctgctt cgagaaagcc attcttggct ggtgcgaacg
     7561 ttacggcgtc tgacctacat gttc
//
LOCUS       DACAOP010000154         7577 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.154, whole genome shotgun sequence.
ACCESSION   DACAOP010000154 DACAOP010000000
VERSION     DACAOP010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7577
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.154"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..1582
                     /locus_tag="IT892_004208"
     CDS             <1..1582
                     /locus_tag="IT892_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-NAD(P)-binding protein"
                     /protein_id="HAP3137340.1"
                     /translation="AGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKM
                     MLANIASIEIPPIYCTYLEWLQKQEDSHLQRYGVKKETLHDRQFLPRILLGEYFRDQF
                     LRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPD
                     EEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVV
                     FHRDNASEKLNITLLSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRV
                     FRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKR
                     EKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLA
                     LREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGL
                     REQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAM
                     ARAVVKPASRARRRLSFD"
     gene            complement(1594..2406)
                     /locus_tag="IT892_004209"
     CDS             complement(1594..2406)
                     /locus_tag="IT892_004209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137341.1"
                     /translation="MIITQADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYT
                     DWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGERPFCSQFARSDDHARIGCCED
                     NARITTAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRI
                     ANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTG
                     VVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC"
     gene            complement(2410..3195)
                     /locus_tag="IT892_004210"
     CDS             complement(2410..3195)
                     /locus_tag="IT892_004210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HAP3137342.1"
                     /translation="MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVL
                     GLHALLRARGVKKSATDHGEKIYLYSKAVRLWHWSNALLFVLLLASGLINHFAMVGAT
                     AVKSLVAVHEVCGFLLLACWLGFVLINAVGDNGHHYRIRRQGWLERAAKQTRFYLFGI
                     MQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYW
                     LLQTHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH"
     gene            complement(3192..3860)
                     /locus_tag="IT892_004211"
     CDS             complement(3192..3860)
                     /locus_tag="IT892_004211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416186.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HAP3137343.1"
                     /translation="MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDES
                     RCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCID
                     VCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLA
                     KGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIK
                     KENV"
     gene            complement(3924..4562)
                     /locus_tag="IT892_004212"
     CDS             complement(3924..4562)
                     /locus_tag="IT892_004212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhW family putative oxidoreductase system
                     protein"
                     /protein_id="HAP3137344.1"
                     /translation="MNHQDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAE
                     FIRQHSAAGQLVARAVFLSPPYLVAEEELSVLLESIKQNGDYADIACLTGSKDDYYYS
                     TQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEA
                     AIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP"
     gene            complement(4575..6677)
                     /locus_tag="IT892_004213"
     CDS             complement(4575..6677)
                     /locus_tag="IT892_004213"
                     /EC_number="1.2.7.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase"
                     /protein_id="HAP3137345.1"
                     /translation="MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDE
                     VPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQ
                     MKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCV
                     AAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKR
                     LNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPP
                     GNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGN
                     TCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYS
                     KGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWN
                     LGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPL
                     KLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTV
                     SPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRN
                     EHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQR
                     LGLEDIAADLAAHNLLPA"
     gene            complement(6698..7324)
                     /locus_tag="IT892_004214"
     CDS             complement(6698..7324)
                     /locus_tag="IT892_004214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein"
                     /protein_id="HAP3137346.1"
                     /translation="MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQE
                     DIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFG
                     DNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCS
                     ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV"
BASE COUNT         1955 a         1986 c         1719 g         1917 t
ORIGIN      
        1 tgccgggcct acggggatct acaccttatt ctcgcttcta cagcaacaaa ctccactttc
       61 tatttctatc ttcgagcagg ctgacgaggc cggtgtcggg atgccataca gtgatgagga
      121 aaactcaaaa atgatgctgg caaatattgc cagtattgaa ataccgccga tttattgtac
      181 gtatctcgaa tggctacaaa agcaagaaga cagccatctc cagcgttatg gcgttaaaaa
      241 agaaaccttg cacgatcgtc agtttttacc gcgaattctg ctgggcgaat atttccgcga
      301 tcaattttta cgactagtag accaggcacg acagcaaaaa tttgcagtgg ctgtttatga
      361 atcatgccag gttaccgatc tgcaaattac aaatgctggc gtcatgctcg ctacaaatca
      421 ggatttaccc agcgagacgt ttgatttagc ggtgatcgcc acgggtcacg tctggcctga
      481 tgaagaagaa gcaacccgaa cgtattttcc cagcccgtgg tcaggcctga tggaagcaaa
      541 ggtcgatgcg tgtaacgtgg gtattatggg aacatccttg agcggactgg atgcggcaat
      601 ggcagtggct attcagcatg gttcgttcat tgaagatgat aaacaacacg tcgtttttca
      661 ccgcgataac gcaagtgaaa agctaaatat cacgttgttg tcgcgcacgg gtattttacc
      721 cgaagccgat ttctattgcc ctattcccta cgagccctta cacatcgtca ccgatcaggc
      781 attaaatgct gagattcaaa aaggcgaaga gggccttttg gatcgggtat ttagattgat
      841 agtagaggaa atcaagtttg ctgatccaga ctggagtcaa cgcatagcct tagagagcct
      901 gaatgtcgat tcctttgctc aagcctggtt tgccgagcgc aaacaacgcg acccatttga
      961 ctgggcagaa aaaaatctcc aggaagtcga acgcaataaa cgagaaaaac atactgttcc
     1021 ctggcgttat gtcattctgc gcctgcatga agccgtacag gaaattgttc cacatctgaa
     1081 tgaacacgac cataaacggt tcagtaaagg ccttgcccgg gttttcatcg ataattatgc
     1141 ggcaatccct tcagagtcta ttcgtcgcct acttgcctta cgtgaagcgg gaatcattca
     1201 tattctcgcc ctcggtgaag actacaaaat ggaaattaat gagtcgcgca ccgtcctgaa
     1261 aacggaagac aacagctact cgtttgacgt ttttattgat gcccgcggac aacgtccgct
     1321 taaagtgaaa gatatccctt tccctgggct acgcgagcaa ttacagaaaa caggggatga
     1381 aatccctgat gttggcgaag attatacgtt acagcaaccc gaagatattc gtgggcgcgt
     1441 agcgttcggc gcgttgccct ggttgatgca cgaccagcct ttcgttcagg gacttacggc
     1501 atgtgcagaa attggtgagg cgatggctcg ggcggtcgta aagcctgcat cccgtgctcg
     1561 tcggcgtctt tcgtttgatt aaaggtaaag ctatcagcac tcaacaaact gatgctgttc
     1621 attaagacga tagcggactc cggctcgaat attgttttca ccttcaatgg cgacggcgaa
     1681 gcgaactctt tcgccgtcat gatatgccag tgcggcgctt cctcctggcc cgagaataat
     1741 tgagtcgacc acgcccgtgc tcactaccgt tgaattttca ccgctggcaa tgatgtgtac
     1801 attgtcgccg ctgttggcaa ttctggcgtt tgcgccaaag ctggcgattt gcaccaggtc
     1861 accattactg gcgacatgac accgttcacc caatgtacaa acgcgtactc gcattccggt
     1921 attcgcaatc cgactgctat ctccagcgct gcttatccgc gaagaattac cggttacagc
     1981 aacccgtgcg cgttcaccgg agctgccaat gtgactgtta aagccgacac ttccaatccg
     2041 cacgctataa cccatactgg caatttgcgc ggcataccca gcggttgtga ttctggcgtt
     2101 atcctcacaa cagccgatgc gagcatgatc gtcgctgcgg gcaaactgac tgcaaaatgg
     2161 tctctctccg gggtctgtgg ccagtttttg catagaggaa acttcctgat gcgcgaagtt
     2221 ttcatccgcc agccattttt tccacgcata ctcaaccaga ctctccgccc agtccgtata
     2281 tccttcctca atcagtgcat gatgaatatc ggcataacta ccgccgcgtg ggaaatggcg
     2341 caggaaccag cgatacatca ccgctccgat acgccattct cgcaggtctg cttgtgtaat
     2401 gatcattcgt tagtgccggt gatagccatc gaccatgctt ttaaaggttt cgtgtggcgt
     2461 acgccccgtg gtgcaaagat aaagatgacc gaagataaaa aagaggctta taaatgccag
     2521 agcaaaatgt gtctgcaata accagtatct tacgccagga aacacatctc ccacggcttg
     2581 cggatagaga cacagcagcc ccgtcaatag taacaacggc agcaatccat acatgacacc
     2641 aacataggcg acctgctgta agggattaaa tttagactgg gttgttgccg ggaaaggatg
     2701 ttcttccccc tgcataatgc caaacaaata aaatcgcgtt tgttttgccg ctcgttccag
     2761 ccacccctga cgacgaatgc gatagtggtg accattatcc ccaacggcat tgatcagcac
     2821 aaagccgagc cagcatgcca gtaacaaaaa tccgcaaact tcatgcaccg caaccagact
     2881 tttaaccgca gttgcgccca ccatcgcaaa gtgatttatc agcccactgg ccagcaacaa
     2941 tacaaagagt aacgcattcg accagtgcca taatctgacc gctttgctgt aaagataaat
     3001 cttctcacca tgatcggtgg ctgatttctt cacgccacga gcacgaagca aggcatgcag
     3061 ccccagcacc aaccacatcc caaccagcaa tactccggca atgatcaacc acaccggcca
     3121 aaattcggga gtgaactgtg gcacatagtt cgctaactgg ctctgaaact gttcagcatg
     3181 ttgcgacggg ttcatacatt ttccttttta atcaaatgtt gaccgaaccg gcgatacaga
     3241 tgcggtttcc cggcaccagg tagctgatat tgatagtatt tattttgctg caaccacgcc
     3301 tgaatttctg ggctatcttc gcgaccaaag atcaatgcgt gttccgggca ggcgctgacg
     3361 caaatgggcg gaaagccttt tgccagtcgg gactcagcgc agaaatcaca tttatctgcc
     3421 actttagtga cagggttaag gtagcgaacc tggtacggac aagcgccaat gcaataactg
     3481 cagccgatgc actgcgattt ttctacccgc acgatcccct gctcatcacg ccacgacgcc
     3541 cccgtcgggc aaacgtcgat gcacggagca tcttcgcagt gctgacatga ctggcgaaaa
     3601 aagtgatact gcgtttcgtt gtcgttatcg gtgactggaa tgtgtgctat cgataaacgg
     3661 cttccctgag cggggacgtg gttagtttta cggcatgcgc gggcgcaaat attacagcca
     3721 ttgcaccgtg actcgtcatg aatcatggca taccgaactt ccttttcttg cctcgtgttc
     3781 gctaacagag aagacgcaga accagtaaaa aagattactg ttcccatccc cagaacaaat
     3841 ttgcgtcgag tgaaggacat ctgattatcc cctaatgcag tggctgcaac tgtccaccct
     3901 atccatgaca tctccctgaa atttcagggg ttctgaaact gctctacctc gaaccattcg
     3961 cataagccat aagccttgcc ataggtcata aatcgctcgc taaacaagta caacaccgcc
     4021 gtcgatgact ccacctgccg tatatcggca tattcaggtg caacatccat cgcggcgatc
     4081 gcggcttcaa tctgcgcttc ctggaagtaa tatggcgctt gcatcagcat ggcgactttg
     4141 taaggacgag gatacgtctg gcactcaaaa cgaacggcgt gtgcaatggc gcgacaaatg
     4201 tcctgctcca caacttgcaa agacatcgcc gcgtagtttt cactcatggc ctgcgttgag
     4261 taatagtaat catccttgct tcccgtcaaa caagcgatat ccgcgtagtc tccgttctgc
     4321 ttaatgcttt ccagcaaaac tgacagttcc tcttctgcaa ccaaataggg tggcgagaga
     4381 aacacggcgc gcgccaccag ctgcccagcc gcagaatgct ggcgaatgaa ctcagccagg
     4441 atttcagcag gttctggttc ggttaccgta tcaacggggt gacgcatccc ctgcaaccat
     4501 tgccgcttcg cctcgtcaac ttcgctgact ttcgctaacg gcaattcatc ctgatggttc
     4561 atcttaccca ttccttacgc aggcagtaga ttgtgtgctg ccagatcggc ggcaatatct
     4621 tccagcccca gacgctgcaa tgtttcgcgg gttggacaac caagctgtgg gtcccagccc
     4681 atttctttgt agaacatcgt gagcgaagca tgcatatcgt cacgatccat tttgtcagta
     4741 ccttcagtaa agaccgggat ctgcggatcc ttgtcgaata cccaggaaca gataagatcg
     4801 tgttcattac gcatatcttt ggtttgcatc agttttaccg tgtaggcacg atgcaacgta
     4861 aaaatacgct ctgcagctaa atctaatttt tcctgagtca tctcttcgcc ggtgatcgct
     4921 ttgaagaatt tggcttcaag cgccagatcg ccccggtaat tacggctttt cagcggcgaa
     4981 acggtcattg gccagaccca gttgcacagg gtgacggcgt tatgcaaaca gacccgcaac
     5041 agcgaccact ttgcatattt aatttttgcg tcattgattg gcgtgtagtt tttggtttca
     5101 tcgtaagcat cttcagaacc aaaaagttct ttcgccactt cacgttgcag tttcaatggc
     5161 aagccggaac caataaagtt gatatgggta tgcgtcatgc agtcacggtt gaacatacag
     5221 ttaacaatgg aaccgacctg cgctgacgct tcattggcat ggtgaaccgg atagccaaac
     5281 ggcgaccaga gtttattttt cgcgtagccc cagtactctt cacccaaatt ccagcgttct
     5341 gcgatggcat atgaaccatc agccaggtga ctcagctcac ccacacgatg cgccagacgg
     5401 tagtaaaaat ctttaatgaa gttaacgtca cccgcttcca gttgatccca gcgaatttct
     5461 gcatactctt cagctggcag aacacgcttg aacacacctt tgctgtaaca ataagtaaag
     5521 tcgcgatgca actgcccgta gttacaccat aggccgtagt catcgaacaa attcagaccc
     5581 accaggttac caatcacacg accatcgtct ttatcttcaa aatctttcgg cccgttcggg
     5641 aagatggtgg tatggacaaa gtttgctaca caagtgttac cacctgtgct gggcacgcca
     5701 aactctttca cccgaggaat attcatttgg gtcatacaac ggatcgggca agagtggcag
     5761 ccgctcattt ttactgtgta tttctctgcc gccggtccta agtcaaaaac ggatttatag
     5821 gtacgaaagc cgaccgtatt ctgattgcct ggcggaattt cacccgtttc aatcggacca
     5881 ccttcagccg cgccccaaaa cagcccttta cgtgctgtcc agcgtgactt gggatctgaa
     5941 tactctgccc acgattgtgg cgtacttggc acgacatggt tgttattcgc accaataagt
     6001 tcagtcatca tgtaatcatt gagacgcttc atctcctgac gatcggcaat gttgacccct
     6061 ttcgtccctt caaccgcaat cgctttcagg tttttcgaac ccattattgc gccagttccc
     6121 gcaccgccgc tgtggttacg gctattcaac atgccagaga gaggaacaag gttttcccca
     6181 gcctgaccaa tagccgccac acaggtttcc ggactggtca atcgacaaat ttcttccgtc
     6241 gttgcgcgcg tcccttttcc ccataagaaa tcggcttttt ccaggctaac tttgtcatct
     6301 ttaatcttca gccataccgg tgatttcgcc ttcccttcga taataatgac gtcgtatcca
     6361 gcgaatttca tttgcgctgc aaaaaagcca cccatatggg catcgacgac taaatttcct
     6421 ttggtaaaag tagaaagtga ggtgatattt acgcgagaac tacagggggc accagatcca
     6481 gttaatgggc cggtagcaaa gactaattta ttcgcttcat cgaaaggttt cgtgcctggc
     6541 ggtacttcgt catacataat tttgtagccg aagcccatgc caccgacaaa acttttaaac
     6601 ttactggaat cttcgagggt aatatttcct gtcgtgagat tgactcttaa tatattacct
     6661 gtccaaccgt tagccatgat tttttccttt gcaagattca cacagtaata tctttccact
     6721 cgataatttt taacgcccct gttgggcagg cgtttgcgca ttcaccgcat aacacacatt
     6781 tcgaggattt tttactttcg gtatttacgg tggccatcat ccacgggcat gccgtagtac
     6841 aggcgctaca gccaatacag cgtttatgat cgacggtaat acagccttct ttctgctgcc
     6901 aggtaatcgc accaatcggg cagacgttca tgcattgcgg ctctttgcat tgacggcagg
     6961 tgtccgcggt atagttgaga tcgccataca ggccgccgcc agagccaacc ccgttgtcgc
     7021 caaagaaata attgcgatgg attttgatac gggagaagaa tgtccctact gagccatcgt
     7081 tgaagttggt acaagagatt tcacagcggt ggcaacccgt gcatcgcgct cgctgggtca
     7141 ccagcacccc tttgggggta tttatcaacc ctactgtgcc gctatcaata tcttcctgtt
     7201 tgcaacccaa aagtgacagt aacgcagggg caattgttag accagcaagg ccttttcctg
     7261 atatacgcaa gaattctaat cgcgttaagc caatatctaa tagtggacga tcaaccgggt
     7321 tcatttattt cgcatcctct tcgcaaacac agtgctgaca attcagcagc ctgatattaa
     7381 gcattcaact aatacgctgc tgactctgtc cccaacacca gatattttcc ctaacccgat
     7441 agtgtatgag aaaagattaa cgccgataaa ctaatccttt atggttagga gaaaaaataa
     7501 tgtgattatt ctgagccctt aacattgatc gttatcaatt aaaattacaa agcaagaaat
     7561 tataagtgaa ctgatat
//
LOCUS       DACAOP010000155         7548 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.155, whole genome shotgun sequence.
ACCESSION   DACAOP010000155 DACAOP010000000
VERSION     DACAOP010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7548
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.155"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            86..1255
                     /gene="prpC"
                     /locus_tag="IT892_004215"
     CDS             86..1255
                     /gene="prpC"
                     /locus_tag="IT892_004215"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HAP3137347.1"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAKHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRPFVALDKRQ"
     gene            1289..2740
                     /gene="prpD"
                     /locus_tag="IT892_004216"
     CDS             1289..2740
                     /gene="prpD"
                     /locus_tag="IT892_004216"
                     /EC_number="4.2.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="HAP3137348.1"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSKVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVASGKVPLTMKQVLTAMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRARLEQMPVNEYLDLYVI"
     gene            2780..4666
                     /gene="prpE"
                     /locus_tag="IT892_004217"
     CDS             2780..4666
                     /gene="prpE"
                     /locus_tag="IT892_004217"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HAP3137349.1"
                     /translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGSV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDGRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALV
                     DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
                     AMEE"
     gene            4996..6255
                     /gene="codB"
                     /locus_tag="IT892_004218"
     CDS             4996..6255
                     /gene="codB"
                     /locus_tag="IT892_004218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HAP3137350.1"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPA
                     IACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEANSVE"
     gene            6245..7528
                     /locus_tag="IT892_004219"
     CDS             6245..7528
                     /locus_tag="IT892_004219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine deaminase"
                     /protein_id="HAP3137351.1"
                     /translation="MSNNALQTIINARLPGEEGLWQIHLQDGKISAIDAQSGVMPITE
                     NSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHHEGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR"
BASE COUNT         1655 a         2022 c         2162 g         1709 t
ORIGIN      
        1 actgaactgt aggtcggata agacgcatag cgtcgcatcc gacaacaatc tcgaccctac
       61 aaatgataac aatgacgagg acaacatgag cgacacaacg atcctgcaaa acagtaccca
      121 tgtcattaaa ccgaaaaaat ctgtggcact ttctggcgtt ccggcgggca atacggcgct
      181 ctgcaccgtg ggtaaaagtg gcaatgacct gcattaccgc ggctacgata ttcttgatct
      241 ggcgaaacat tgcgaatttg aagaagtggc gcatctgctg atccacggca aactgccgac
      301 ccgtgacgaa ctcgccgctt acaaaacgaa actgaaagcc ctgcgcggtt taccggctaa
      361 cgtgcgtacc gtgctggaag ccttaccggc ggcgtcgcac ccgatggatg ttatgcgcac
      421 cggtgtttcc gcgctcggct gcacgctgcc agaaaaagag gggcataccg tctctggcgc
      481 gcgggatatt gccgacaaac tgctggcgtc gcttagctcg attctccttt attggtatca
      541 ctacagccac aacggcgaac gcatccaacc ggaaaccgat gacgactcca tcggcggtca
      601 cttcctgcat ctgctgcacg gcgaaaagcc atcgcaaagc tgggaaaagg cgatgcatat
      661 ctcgctggtg ctgtacgccg aacacgagtt taacgcctcc acctttacca gtcgggtgat
      721 tgcgggcacc ggctctgata tgtattccgc gattattggc gcgattggcg cactgcgcgg
      781 gccaaaacac ggcggggcga atgaagtgtc gctggagatc cagcaacgct acgaaacgcc
      841 ggacgaagcc gaagcagata tccgcaagcg cgtggaaaac aaagaagtgg tcattggttt
      901 tggtcatccg gtttacacca tcgctgaccc gcgccaccag gtgattaaac gtgtggcgaa
      961 gcagctctcg caggaaggcg gctcgctgaa gatgtacaac atcgccgatc gcctggaaac
     1021 ggtgatgtgg gagagcaaaa agatgttccc caatctcgac tggttctctg ctgtttccta
     1081 caacatgatg ggcgttccca ccgagatgtt cacaccactg tttgttatcg cccgcgtcac
     1141 cggctgggcg gcgcacatta tcgaacaacg tcaggacaac aaaattatcc gtccttccgc
     1201 caattatgtt ggaccggaag accgcccgtt tgtcgcgctg gataagcgcc agtaaacctc
     1261 tacgaataac aataaggaaa cgtacccaat gtcagctcaa atcaacaaca tccgcccgga
     1321 atttgatcgt gaaatcgttg atatcgtcga ttacgtcatg aactacgaaa tcagctctaa
     1381 agtggcctac gacaccgcac attactgcct gctcgacacg ctcggctgcg gtctggaagc
     1441 tctcgaatac ccggcctgta aaaaactgct ggggccaatt gttcccggca ccgtcgtacc
     1501 caacggcgtg cgcgtccccg gaactcagtt ccagctcgac cccgtccagg cggcatttaa
     1561 catcggcgcg atgatccgct ggctcgattt caacgatacc tggctggcgg cggagtgggg
     1621 ccatccttcc gacaacctcg gcggcattct ggcaacggcg gactggcttt cgcgcaacgc
     1681 ggtcgccagc ggcaaagtgc cgttgaccat gaaacaggtg ctgaccgcaa tgatcaaagc
     1741 ccatgaaatt cagggctgca tcgcgctgga aaactccttt aaccgcgtcg gcctcgacca
     1801 cgttctgtta gtgaaagtgg cttccaccgc cgtggtcgcc gaaatgctcg gcctgacccg
     1861 cgaggaaatt ctcaacgccg tttcgctggc gtgggtggac ggtcagtcgc tgcgcaccta
     1921 tcgccatgcg ccgaacaccg gcacgcgtaa atcctgggcg gcgggcgatg ccacttcccg
     1981 cgcggtacgt ctggcactga tggcgaaaac gggcgaaatg ggttacccgt cagccctgac
     2041 tgcgccggtg tggggcttct acgacgtctc ctttaaaggt gaatcgttcc gcttccagcg
     2101 cccgtacggt tcctacgtta tggaaaatgt gctgttcaaa atctccttcc cggcggagtt
     2161 ccactcccag acggcagttg aagcagcgat gacgctctat gaacagatgc aggcagcagg
     2221 caaaacggcg gcggatatcg aaaaagtgac cattcgcacc cacgaagcct gtattcgcat
     2281 catcgacaaa aaagggccgc tcaataaccc ggcagaccgc gatcactgca ttcagtacat
     2341 ggtggcgatc ccgctgctat tcgggcgctt aacggcggca gattacgagg acaacgttgc
     2401 gcaagataaa cgcattgacg ccctgcgcga gaagatcaat tgctttgaag atccggcatt
     2461 taccgctgac taccacgacc cggaaaaacg cgccatcgcc aatgccatta cccttgagtt
     2521 caccgacggc acacgatttg aagaagtggt ggtggagtac cccattggtc atgctcgccg
     2581 ccgtcaggat ggtattccga aactggtcga taaattcaaa atcaatctcg cgcgccagtt
     2641 cccgactcgc caacagcagc gcattctgga ggtttctctc gacagagctc gcctggaaca
     2701 gatgccggtc aatgagtatc tcgacctgta cgtcatttaa gtaaacggcg gtaaggcgta
     2761 agttcaacag gagagcatta tgtcttttag cgaattttat cagcgttcga ttaacgaacc
     2821 ggagcagttc tgggccgagc aggcccggcg tattgactgg cagacgccct ttacgcaaac
     2881 gctcgatcac agcaatccgc cgtttgcccg ttggttttgt gaaggccgaa ccaacttgtg
     2941 ccacaacgcc atcgaccgct ggctggagaa acagccagag gcgctggcgc tgattgccgt
     3001 ctcttcggaa acagaagaag agcgcacctt tacctttcgt cagctgcatg acgaagtgaa
     3061 cgcggtggcc tcaatgttgc gttcattggg tgtgcagcgc ggcgatcggg tgctggtgta
     3121 tatgccgatg attgccgaag cgcatattac tctgctggcc tgcgcgcgca ttggcgctat
     3181 tcactcggtg gtgtttggtg gatttgcctc gcacagcgtg gcggcgcgaa ttgatgacgc
     3241 taaaccggtg ctgattgtct cggctgatgc cggagcgcgc ggtggcaaaa tcattcccta
     3301 taaaaaattg ctcgacgatg cgataagtca ggcgcagcac cagccacgcc atgttttgct
     3361 ggtggatcgc gggctggcga aaatggcgcg cgtcagcggg cgggatgtcg atttcgcgtc
     3421 gttgcgccat caacacatcg gcgcgcgggt accggtggcg tggctggaat ccaacgaaac
     3481 ctcctgcatt ctctacactt ccggcacgac cggcaaacct aaaggcgtgc agcgtgacgt
     3541 cggcggatat gcggtggcgc tggcgacctc gatggacacc atttttggcg gcaaagcggg
     3601 cagcgtgttc ttttgcgcat cggatatcgg ctgggtggtg gggcattcgt atatcgttta
     3661 cgcgccgctg ctggcgggga tggcgactat cgtttacgaa ggattgccga cctggccgga
     3721 ctgcggcgtg tggtggaaaa tcgtcgagaa atatcaggtt agccggatgt tctcagcgcc
     3781 gaccgccatt cgcgtgctga aaaaattccc taccgctgaa attcgcaaac acgatctctc
     3841 gtcgctggaa gtgctctatc tggctggaga accgctggac gagccgaccg ccagttgggt
     3901 gagcaatacg ctggatgtgc cggtcatcga caactactgg cagaccgaat ccggctggcc
     3961 gattatggcg attgctcgcg gtctggacga caggccgacg cgtctgggaa gccccggtgt
     4021 gccgatgtat ggctataacg tgcagttgct taatgaagtc accggcgaac cgtgtggcgt
     4081 caacgagaaa gggatgctgg tggtggaagg gccgctgccg ccggggtgta ttcagaccat
     4141 ctggggcgac gacggccgct ttgtgaagac ttactggtcg ctgttttccc gcccggtgta
     4201 cgccaccttt gactggggca tccgtgacgc tgacggttat cactttattc tcgggcgcac
     4261 tgacgatgta attaacgttg ccgggcatcg gctggggacg cgcgagattg aagagagtat
     4321 ctccagccat ccgggcgttg ccgaagtggc ggtggttggg gtgaaagatg cgctgaaagg
     4381 gcaggtggcg gtggcgtttg tcattccgaa agagagcgac agtctggaag atcgtgatgt
     4441 ggcgcactcg caagagaagg cgattatggc gctggtggac agccagattg gcaactttgg
     4501 ccgcccggcg cacgtctggt ttgtctcgca attgccaaaa acgcgatccg gaaaaatgct
     4561 gcgccgcacg atccaggcga tttgcgaagg acgcgatcct ggagatctga cgaccattga
     4621 tgatcctgcg tcgttggatc agatccgcca ggcgatggaa gagtaggtta ttgtcggatg
     4681 cgtcgcgcgg tgcatccggc actgtgtgcc gatgcctgat gcgacgctga cgcgttttat
     4741 catgcctacg gacctgaacc gtaggtcgga taaggcgctc gcgtcgcatc cgacaccatg
     4801 ctcagatgcc tgatgcgacg ctgacgcgtc ttatcaggcc tacccactgt ttttacaccg
     4861 ataatttttc ccccaccttt ttgcactcat tcatataaaa aatatatttc cccacgaaaa
     4921 cgattgcttt ttatcttcag atgaatagaa tgcggcggat tttttgggtt tcaaacagca
     4981 aaaaggggga atttcgtgtc gcaagataac aactttagcc aggggccagt cccgcagtcg
     5041 gcgcggaaag gggtattggc attgacgttc gtcatgctgg gattaacctt cttttccgcc
     5101 agtatgtgga ccggcggcac tctcggaacc ggtcttagct atcatgattt cttcctcgca
     5161 gttctcatcg gtaatcttct cctcggtatt tacacttcat ttctcggtta cattggcgca
     5221 aaaaccggcc tgaccactca tcttcttgct cgcttctcgt ttggtgttaa aggctcatgg
     5281 ctgccttcac tgctactggg cggaactcag gttggctggt ttggcgtcgg tgtggcgatg
     5341 tttgccattc cggtgggtaa ggcaaccggg ctggatatta atttgctgat tgccgtttcc
     5401 ggtttactga tgaccgtcac cgtctttttt ggcatttcgg cgctgacggt tctttcggtg
     5461 attgcggttc cggctatcgc ctgcctgggc ggttattccg tgtggctggc tgttaacggc
     5521 atgggcggcc tggacgcatt aaaagcggtc gttcccgcac aaccgttaga tttcaatgtc
     5581 gcgctggcgc tggttgtggg gtcatttatc agtgcgggta cgctcaccgc tgactttgtc
     5641 cggtttggtc gcaatgccaa actggcggtg ctggtggcga tggtggcctt tttcctcggc
     5701 aactcgttga tgtttatttt cggtgcagcg ggcgctgcgg cactgggcat ggcggatatc
     5761 tctgatgtga tgattgctca gggcctgctg ctgcctgcga ttgtggtgct ggggctgaat
     5821 atctggacca ccaacgataa cgcactctat gcgtcgggtt taggtttcgc caacattacc
     5881 gggatgtcga gcaaaaccct ttcggtaatc aacggtatta tcggtacggt ctgcgcatta
     5941 tggctgtata acaattttgt cggctggttg accttccttt cggcagctat tcctccagtg
     6001 ggtggcgtga tcatcgccga ctatctgatg aaccgtcgcc gctatgagca ctttgcgacc
     6061 acgcgtatga tgagtgtcaa ttgggtggcg attctggcgg tcgccttggg gattgctgca
     6121 ggccactggt taccgggaat tgttccggtc aacgcggtat taggtggcgc gctgagctat
     6181 ctgatcctta acccgatttt gaatcgtaaa acgacagcag caatgacgca tgtggaggct
     6241 aacagtgtcg aataacgctt tacaaacaat tattaacgcc cggttaccag gcgaagaggg
     6301 gctgtggcag attcatctgc aggacggaaa aatcagcgcc attgatgcgc aatccggcgt
     6361 gatgcccata actgaaaaca gcctggatgc cgaacaaggt ttagttatac cgccgtttgt
     6421 ggagccacat attcacctgg acaccacgca aaccgccgga caaccgaact ggaatcagtc
     6481 cggcacgctg tttgaaggca ttgaacgctg ggccgagcgc aaagcgttat taacccatga
     6541 cgatgtgaaa caacgcgcat ggcaaacgct gaaatggcag attgccaacg gcattcagca
     6601 tgtgcgtacc catgtcgatg tttcggatgc aacgctaact gcgctgaaag caatgctgga
     6661 agtgaagcag gaagtcgcgc cgtggattga tctgcaaatc gtcgccttcc ctcaggaagg
     6721 gattttgtcg tatcccaacg gtgaagcgtt gctggaagag gcgttacgct taggggcaga
     6781 tgtagtgggg gcgattccgc attttgaatt tacccgtgaa tacggcgtgg agtcgctgca
     6841 taaaaccttc gccctggcgc aaaaatacga ccgtctcatc gacgttcact gtgatgagat
     6901 cgatgacgag cagtcgcgct ttgtcgaaac cgttgctgcc ctggcgcacc atgaaggcat
     6961 gggcgcgcga gtcaccgcca gccacaccac ggcaatgcac tcctataacg gggcgtatac
     7021 ctcacgcctg ttccgcttgc tgaaaatgtc cggtattaac tttgtcgcca acccgctggt
     7081 caatattcat ctgcaaggac gtttcgatac gtatccaaaa cgtcgcggca tcacgcgcgt
     7141 taaagagatg ctggagtccg gcattaacgt ctgctttggt cacgatgatg tcttcgatcc
     7201 gtggtatccg ctgggaacgg cgaatatgct gcaagtgctg catatggggc tgcatgtttg
     7261 ccagttgatg ggctacgggc agattaacga tggcctgaat ttaatcaccc accacagcgc
     7321 aaggacgttg aatttgcagg attacggcat tgccgccgga aacagcgcca acctgattat
     7381 cctgccggct gaaaatgggt ttgatgcgct gcgccgtcag gttccggtac gttattcggt
     7441 acgtggcggc aaggtgattg ccagcacaca accggcacaa accaccgtat atctggagca
     7501 gccagaagcc atcgattaca aacgttgaac gactgggtta cagcgagc
//
LOCUS       DACAOP010000156         7270 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.156, whole genome shotgun sequence.
ACCESSION   DACAOP010000156 DACAOP010000000
VERSION     DACAOP010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7270
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.156"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(152..1744)
                     /gene="lsrK"
                     /locus_tag="IT892_004220"
     CDS             complement(152..1744)
                     /gene="lsrK"
                     /locus_tag="IT892_004220"
                     /EC_number="2.7.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416028.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer-2 kinase"
                     /protein_id="HAP3137352.1"
                     /translation="MARLFTLSESKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWR
                     HLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIAPEYIAAVSACSMREGIVLYNNE
                     GAPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSD
                     IYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADIL
                     SPVKETGTLLGVVSSQAAELCGLKAGTPVVVGGGDVQLGCLGLGVVRPAQTAVLGGTF
                     WQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLIAE
                     RLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKAT
                     LFRALEENAAIVSACNLQQIADFSNIHPSSLVFAGGGSKGKLWSQILADVSGLPVNIP
                     VVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTHTPDPEKHELYQDSRDKWQAV
                     YQDQLGLVDHGLTTSLWKAPGL"
     gene            complement(1823..2776)
                     /gene="lsrR"
                     /locus_tag="IT892_004221"
     CDS             complement(1823..2776)
                     /gene="lsrR"
                     /locus_tag="IT892_004221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LsrR"
                     /protein_id="HAP3137353.1"
                     /translation="MTINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTR
                     LKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRL
                     GIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
                     GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDD
                     ATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTI
                     PVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS"
     gene            3025..4560
                     /gene="lsrA"
                     /locus_tag="IT892_004222"
     CDS             3025..4560
                     /gene="lsrA"
                     /locus_tag="IT892_004222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter ATP-binding
                     protein LsrA"
                     /protein_id="HAP3137354.1"
                     /translation="MQTSDTRALPLLCARSVYKQYSGVNVLKGIDFTLHQGEVHALLG
                     GNGAGKSTLMKIIAGITPADSGTLEIEGNNYVRLTPVHAHQLGIYLVPQEPLLFPSLS
                     IKENILFGLAKKQLSMQKMKNLLAALGCQFDLHSLAGSLDVADRQMVEILRGLMRDSR
                     ILILDEPTASLTPAETERLFSRLQELLATGVGIVFISHKLPEIRQIADRISVMRDGTI
                     ALSGKTSELSTDDIIQAITPAVREKSLSASQKLWLELPGNRPQHAAGTPVLTLENLTG
                     EGFRNVSLTLNAGEILGLAGLVGAGRTELAETLYGLRTLRGGRIMLNGKEINKLSTGE
                     RLLRGLVYLPEDRQSSGLNLDASLAWNVCALTHNLRGFWAKTAKDNATLERYRRALNI
                     KFNQPEQAARTLSGGNQQKILIAKCLEASPQVLIVDEPTRGVDVSARNDIYQLLRSIA
                     AQNVAVLLISSDLEEIELMADRVYVMHQGEITHSALTERDINVETIMRVAFGDSQRQE
                     ASC"
     gene            4554..5582
                     /gene="lsrC"
                     /locus_tag="IT892_004223"
     CDS             4554..5582
                     /gene="lsrC"
                     /locus_tag="IT892_004223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrC"
                     /protein_id="HAP3137355.1"
                     /translation="MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSA
                     QILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVATLLLGLLA
                     GFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLLGVS
                     AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMA
                     ALTGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQID
                     SVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALERNLRRQKYARFMTPPPSVKPAS
                     SGKKREAA"
     gene            5582..6574
                     /gene="lsrD"
                     /locus_tag="IT892_004224"
     CDS             5582..6574
                     /gene="lsrD"
                     /locus_tag="IT892_004224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrD"
                     /protein_id="HAP3137356.1"
                     /translation="MRIRYGWELALAALLVIEIVAFGAINPRMLDLNMLLFSTSDFIC
                     IGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGALCGL
                     INAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDV
                     LGLPVPLIIFLICLLVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMT
                     GLASAVAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLV
                     GYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEWLARRANNPLP"
     gene            6586..>7270
                     /gene="lsrB"
                     /locus_tag="IT892_004225"
     CDS             6586..>7270
                     /gene="lsrB"
                     /locus_tag="IT892_004225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein LsrB"
                     /protein_id="HAP3137357.1"
                     /translation="MTLHRFKKIALLSALGIAAISMNVQAAERIAFIPKLVGVGFFTS
                     GGNGAQQAGKELGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPAL
                     KRAMQRGVRVLTWDSDTKPECRSYYINQGTPAQLGGMLVDMAARQVNKDKAKVAFFYS
                     SPTVTDQNQWVKEAKAKIAKEHPGWEIVTTQFGYNDATKSLQTAEGILKAYSDLDAII
                     APDANALPAA"
BASE COUNT         1685 a         1877 c         1864 g         1844 t
ORIGIN      
        1 aatagcaatt ttctcttgaa tatagtactg gtgatggaac gatgaatctg caagctggct
       61 tttaacaagc cagctctaaa agaagggaaa taagaataac tatactcaaa aactaacagc
      121 cacggtcatc atgatgtggc tgtcaatgaa actataaccc aggcgctttc cataacgacg
      181 tcgtcagtcc atgatcaacc agccccagct gatcctgata aactgcctgc cacttatcgc
      241 gtgaatcctg ataaagttca tgcttttccg ggtctggtgt gtgcgtccgt tcccagcgaa
      301 ccaggcgttc tccggtttct gccattgatg aaaaaattcc ggcaccgacg ccagctgcaa
      361 tggcacatcc taatgcagtg gcttctttga ccaccggaat attgacgggt aatcccgaga
      421 catcagcgag aatttgactc cataatttcc cttttgaacc tccgcctgca aagactaacg
      481 atgaaggatg aatattcgag aaatcagcaa tttgctgcaa gttacacgct gatacaatcg
      541 ccgcattttc ttccagcgca cggaacaatg tcgctttgtt acatttatcc gggtcaatgg
      601 acaagttaat aaaggaaggc gcagcgtgat accaggtttt aaagcgcatt ctgtcggaga
      661 agatcggcat tacgccccac gacccaggcg gcacccgact ggccatctct tccagcagcg
      721 tataggtgtc gatgcctaaa cgttcggcaa tcagtttttc ttcggcacag aaagcatcgc
      781 ggaaccagcg catggtgagt ccggtaaaaa agcttataga ttcagcttgt accatgccag
      841 gaataacatg aggattaacg cgcacgttca tttctgggtc tgtcaccggc gcggctaaat
      901 ttacaacttg ctgccagaat gtgccgccaa gaaccgcggt ttgtgccgga cgcacaacgc
      961 ctaacccaag gcaaccaagc tgcacgtcgc ctcctccaac gaccaccgga gtgcccgcct
     1021 tcagaccgca gagttccgcc gcttgtgaac ttaccacgcc cagcaatgtg ccggtttctt
     1081 tgacaggaga aagaatatcg gcacgtaggc cagccatatc cagcaatgca ggtttccagt
     1141 cacgggtggt tagatcaaga agtcccgtgg tgccagcgtt agagggatcc accgccagtt
     1201 cgccgctgag catataggcc agccagtcgc tgatcatggt gatggttgat gcctgacggt
     1261 aaatatcgga acgatggtgc gccagccaaa gtaatctggg gatggcactt aaagccagtg
     1321 tttgtccggt cgcgcgataa acttcgtttt caaaggtatt gttgtgcagt tctttaagtt
     1381 cgctaacttc gcgtgccgct ctggcatcca cattggcgca ggcccagatc ggggctcctt
     1441 cattattata taaaacaatg ccttcacgca tcgaacatgc cgaaacggca gcgatatact
     1501 ccggggctat gccggcgttg tgcagcgcct ggcgcataca ctcacacgcc agttgccagt
     1561 ttttgttgag atcaaattcc atagaaccag gaacgtccgg tactgccaga tgccgccact
     1621 ccgcctgtcc cactgctatt tgattgcctt ccaggtcgaa tatcacagcc cgaatacttc
     1681 cggtgcctgc atccagcgcc atcaggtagt actttgattc tgaaagggta aagagtcgag
     1741 ccattagatt atcctcggct tatgcgttct gtctgttcct ctatacgttc tccatcattc
     1801 ccggtaataa ggtcatgcaa atttaactac gtaaaatcgc cgctgctgtg tcctgatcgg
     1861 taaccagtgc gttgatataa ccgcctttca ttgcagcggc aattgcttcg gctttatttt
     1921 ctccccctgc cacgccaacc cggacgggta tggtcttcag cgcgcttaaa ggtaagccaa
     1981 tcagttcgtt atgtattttg atattcgtga caacgtcacc ttttgcatca aaaaagtagc
     2041 ctaaaatgtc gccaaccgcc ccttttcggc caatcattaa ctgttcgccc tggctgatat
     2101 aaccggagcg aatgattgtc gcatcgtcct gttgactcac agcaccaatg ccgacaatcg
     2161 ccacatccgc tgcttgcgcg gctaacagaa catctttgac gcaattttca ttttttagcg
     2221 tacgggcaat gtcagcggag gatgcccgca acggagccgg aataatattc acactgcacg
     2281 ccgcgttaag ctgcccgatt cccgtcatat aagaaccgac gccaccggag agcgtgacca
     2341 ggcgaatttg ctgtgacgaa ataaaaccac ttaagcgttg cagcgtattc atggttgcct
     2401 cgccaaaacc aatcgccagc atctgttgtg gttgaagtaa actcatcaac atatgcgccg
     2461 cgcctatccc cagtcgccca ccgacatcag catccgcaag cccagggatc acccggacat
     2521 gttgcagcga aaactgacga cgtaattgag tttcatattc cagacagcct tcaaagcgag
     2581 aattaatctg tacgcgaata atgccggact gatgcccttt ctccagcaat cgcgacactt
     2641 tcaaacgtgt caggccgaga cgatcgctga tctcgctctg ggtcagcccg tcgtgatagt
     2701 aaaaccacgc gatccgcgcg acctgttctt cttcacacat tccctgttct gaaattgccg
     2761 aatcgttgat tgtcataatt cattcttcac tttgaacata tttaaatctt taatgcaatt
     2821 gttcagttct tgctcattta tatctgtgat ggcaaccaca gtttgactct acgagcatga
     2881 acaaacgcaa ccgtgaaaat caaaatagca taaattgtga tctattcgtc ggaaatatgt
     2941 gcaatgtcca cctaaggtta tgaacaaatt aaaagcagaa atacatttgt tcaaaactca
     3001 cctgcaaaac tgaacggggg aaatatgcaa acgagtgata cccgcgcgtt accgctactt
     3061 tgcgcccgct cggtttataa acagtattca ggggtcaatg tcctgaaagg catcgatttt
     3121 acgttgcatc agggggaggt ccacgccctg ctcggcggca atggtgccgg taaatcgacg
     3181 ttaatgaaga ttattgccgg tattacccct gctgatagcg gtacgctgga gattgagggc
     3241 aacaactacg tcagattaac gccagttcat gctcatcagc tgggtattta tctcgttccc
     3301 caggaaccgc tgcttttccc aagcctgtcg ataaaagaaa acatcctgtt tgggctggca
     3361 aaaaaacagc tctccatgca gaaaatgaag aacttgctgg cggcgctggg ctgccagttt
     3421 gatctgcata gtctggcagg atcgctggat gtcgccgatc gccaaatggt ggaaatcctc
     3481 cgcgggctga tgcgcgactc gcggattctg atcctcgatg aacctaccgc ctcgcttacc
     3541 cctgcggaaa ccgaacgctt gtttagtcgc ttgcaagagc tgcttgctac tggcgtgggt
     3601 attgttttta tctcgcataa gctgccggaa attcgccaga ttgccgatcg aattagcgtg
     3661 atgcgcgacg gaaccatcgc cttaagcggc aaaaccagcg aactgtctac cgacgacatt
     3721 attcaggcca tcaccccagc ggtacgggaa aaatcgctct ctgccagcca aaaattatgg
     3781 ctggagttac ctggtaaccg cccacaacat gccgccggaa cgccggtgct gacactggaa
     3841 aatctgaccg gcgaaggttt caggaatgtc agcctgacgc tcaatgccgg agaaattctg
     3901 ggcctggctg ggctggtggg ggccggacgc acagaactgg ccgagacgct ctatggtctg
     3961 cgtactttgc gtggcggacg cattatgctg aatggtaaag agatcaataa attatccact
     4021 ggagaacgtt tactgcgcgg tctggtttat ctgccggaag atcgccagtc atccggactg
     4081 aatctcgatg cttcgctggc ctggaacgtc tgcgccctta ctcataacct tcgtggattc
     4141 tgggcgaaaa ccgcgaaaga taatgccacc ctggaacgtt atcgtcgggc gctgaatatt
     4201 aaattcaacc aaccggaaca agctgcacgg acattatccg gtggcaacca gcaaaaaatc
     4261 ctcattgcca aatgcctgga agcttcgccg caagtattga ttgtcgatga gccgacgcgc
     4321 ggcgtggatg tctcggcccg taatgatatc taccagctgt tgcgcagcat cgccgcacaa
     4381 aatgtggctg tgctgcttat ctcctccgac ctggaagaga tcgaactgat ggcagatcgt
     4441 gtgtatgtga tgcatcaggg cgaaattacc cactctgcac tgaccgagcg cgatattaat
     4501 gtcgagacta ttatgcgcgt tgccttcggc gatagtcagc gtcaggaggc gtcatgctga
     4561 agtttattca gaacaaccgt gaaatcacgg cactgctggc ggtggtgctg ctgtttgtat
     4621 tacccggttt tctcgaccgc cagtatttaa gtgtgcaaac gctgaccatg gtttatagca
     4681 gcgcgcaaat cctgatcctg ctggcaatgg gcgcgacgct ggtaatgctt acgcgcaata
     4741 ttgatgtttc agtgggttcg attaccggaa tgtgcgcggt gctgttgggg atgttactga
     4801 acgcaggata ttcactacct gttgcttgtg tcgcgacttt actgcttggt ttgctcgcgg
     4861 gatttttcaa cggtgtcctg gtcgcgtggc taaagatccc tgccattgtt gccacccttg
     4921 gcacgttagg gttgtacaga ggcatcatgt tgctgtggac tggcggcaaa tggattgaag
     4981 ggttacccgc cgaactgaaa cagctctccg ccccgctgct gcttggcgtt tcagcaattg
     5041 gttggttgac gataattctg gtggcattta tggcctggct gctggcaaag acggcgtttg
     5101 gacgcagttt ttatgccacg ggcgataatt tacagggcgc tcgtcaactg ggcgttcgta
     5161 ctgaagccat tcgcattgtg gcattttcgt tgaacggctg catggcggca ctgacgggaa
     5221 ttgtgtttgc ttcgcagatt ggttttatcc ccaaccagac cggtaccggg ctggagatga
     5281 aagcaattgc agcctgcgtg ctgggcggca ttagtttgct cggtggttcc ggtgcgatca
     5341 ttggtgcggt actcggcgca tggttcctga cgcagatcga tagcgtactg gtgctgttgc
     5401 gcattccggc atggtggaat gattttatcg cgggtctggt tctgctggcg gtgctggtgt
     5461 ttgatggacg cctgcgttgt gcgctggaac gtaatctacg gcggcaaaaa tatgcccgct
     5521 ttatgacgcc accgccatcc gttaaacccg cttcgtcagg taaaaaacgg gaggccgcat
     5581 aatgcgtatt cgctacggtt gggaactggc tcttgccgca ctgctcgtta ttgagattgt
     5641 cgcatttggt gcaattaacc cgcgaatgtt agatctcaat atgttgctgt tcagcaccag
     5701 tgactttatc tgcattggca ttgtcgccct accgctaacg atggtgattg tcagtggcgg
     5761 gatcgatatt tcgtttggtt cgaccatcgg cctctgcgcc attgcattgg gcgtactgtt
     5821 tcaaagtggt gtgccgatgc cgctggcgat actcctgacc ttactgctcg gcgcattgtg
     5881 cgggctgatc aacgccggat taattatcta taccaaagtt aacccgctgg tgattacgct
     5941 tggcacgctg tatctgtttg ccggaagcgc tctgctgctt tccggtatgg ccggagcgac
     6001 ggggtacgaa ggtattggtg gattcccgat ggcgtttaca gatttcgcta acctggatgt
     6061 gctgggactc cccgttccgc tgattatctt cctgatatgt ctcctcgttt tctggctctg
     6121 gctgcataaa acccatgccg gacgtaatgt gtttttgatt gggcaaagcc cgcgcgtggc
     6181 gctttatagc gcgattccag ttaaccgtac cttatgtgcg ctctatgcca tgacggggct
     6241 ggcgtctgcg gtcgccgctg tgctgctggt atcgtatttt ggttcagcac gttccgatct
     6301 cggtgcgtcg tttctgatgc ccgccatcac cgccgtggtg cttggcgggg ccaatattta
     6361 tggtggttcc ggttccatta tcggcaccgc cattgcggtt ttattagtgg gatatttgca
     6421 acaaggtttg caaatggcag gagtgccaaa tcaggtgtcc agcgcccttt ccggtgcgct
     6481 acttatcgtc gttgtcgtag gtcgttccgt tagcctgcat cgccagcaaa ttaaagagtg
     6541 gctggcgcgt cgggccaata acccattgcc ataaaggata tcttcatgac acttcatcgc
     6601 tttaagaaaa tcgccttact tagcgctctt ggcattgccg caatctctat gaatgtgcag
     6661 gccgcagagc gtattgcatt tattcccaaa ctggttggcg tgggattttt taccagcggt
     6721 ggcaacggcg cacaacaagc gggtaaagag ctgggcgttg atgtgaccta cgacgggccg
     6781 acagaaccca gtgtttctgg tcaggtacag ttgattaata acttcgtcaa tcaaggttat
     6841 aacgccatta tcgtttctgc ggtttcgcct gatggcttgt gtccggcact gaaacgcgcc
     6901 atgcaacgtg gtgtgagagt gctgacctgg gactctgata ctaaaccgga gtgccgctct
     6961 tactacatta atcagggaac gcccgcccag ttaggaggta tgttggtgga tatggcggcg
     7021 cgtcaggtga ataaagacaa agccaaagtc gcgtttttct actcaagccc caccgttacg
     7081 gaccaaaacc agtgggtgaa agaagcgaaa gcgaaaatcg ccaaagagca tccaggctgg
     7141 gaaattgtca ctacgcagtt tggctataac gatgccacta aatcgttaca aaccgcagaa
     7201 ggaatattaa aagcgtatag cgatctcgac gccattatcg cccccgatgc caacgccctg
     7261 cccgctgccg
//
LOCUS       DACAOP010000157         7239 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.157, whole genome shotgun sequence.
ACCESSION   DACAOP010000157 DACAOP010000000
VERSION     DACAOP010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7239
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.157"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            96..356
                     /gene="dinJ"
                     /locus_tag="IT892_004226"
     CDS             96..356
                     /gene="dinJ"
                     /locus_tag="IT892_004226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin DinJ"
                     /protein_id="HAP3137358.1"
                     /translation="MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVARE
                     KALPFDLREPNQLTIQSIKNSEAGIDVHKAKDADDLFDKLGI"
     gene            359..637
                     /gene="yafQ"
                     /locus_tag="IT892_004227"
     CDS             359..637
                     /gene="yafQ"
                     /locus_tag="IT892_004227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafQ"
                     /protein_id="HAP3137359.1"
                     /translation="MIQRDIEYSGQYSKDVKLAQKRHKDMNKLKYLMTLLINNTLPLP
                     AVYKDHPLQGSWKGYRDAHVEPDWILIYKLTDKLLRFERTGTHAALFG"
     gene            793..1533
                     /locus_tag="IT892_004228"
     CDS             793..1533
                     /locus_tag="IT892_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HAP3137360.1"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     gene            complement(1504..2271)
                     /locus_tag="IT892_004229"
     CDS             complement(1504..2271)
                     /locus_tag="IT892_004229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HAP3137361.1"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV"
     gene            complement(2477..3055)
                     /gene="lpcA"
                     /locus_tag="IT892_004230"
     CDS             complement(2477..3055)
                     /gene="lpcA"
                     /locus_tag="IT892_004230"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HAP3137362.1"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     gene            3295..5739
                     /locus_tag="IT892_004231"
     CDS             3295..5739
                     /locus_tag="IT892_004231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HAP3137363.1"
                     /translation="MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALVKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     gene            complement(5782..6255)
                     /gene="ivy"
                     /locus_tag="IT892_004232"
     CDS             complement(5782..6255)
                     /gene="ivy"
                     /locus_tag="IT892_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-lysozyme inhibitor"
                     /protein_id="HAP3137364.1"
                     /translation="MGRISSGGMMFKAITTVAALVIATSAMAQDDLTISSLAKGETTK
                     AAFNQMVQGHKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEK
                     SNQMTGLFSTIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     gene            6409..7179
                     /gene="yafV"
                     /locus_tag="IT892_004233"
     CDS             6409..7179
                     /gene="yafV"
                     /locus_tag="IT892_004233"
                     /EC_number="3.5.1.111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutaramate amidase"
                     /protein_id="HAP3137365.1"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAL
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMAALREYREKFPAWQDADEFRLW"
BASE COUNT         1720 a         1828 c         1933 g         1758 t
ORIGIN      
        1 aaacatccgt ttattaaatt actcatggat tgtcgctgtt gctcatttga gctacaattc
       61 aagctgaata aatatacagc acaggagata ccccaatggc tgctaacgcg tttgttcgcg
      121 cccgaatcga tgaagatctg aagaatcagg cagcggacgt actggccggg atggggctga
      181 ccatctctga cctggttcgc ataaccctca caaaggtcgc gcgtgaaaag gcattgccgt
      241 ttgatttacg cgagcctaat caattaacca ttcaatcaat caaaaacagc gaagctggca
      301 ttgatgttca taaggccaaa gacgccgatg atttatttga taaattagga atttaaatat
      361 gattcaaagg gatattgaat actcgggaca atattcaaag gatgtaaaac ttgcacaaaa
      421 gcgtcataag gatatgaata aattgaaata tcttatgacg cttcttatca ataatacttt
      481 accgcttcca gctgtttata aagaccaccc gctgcaaggt tcatggaaag gttatcgcga
      541 tgctcatgtc gaaccggact ggatcctgat ttacaaactt accgataaac ttttacgatt
      601 tgagagaact ggaactcacg cggcgctctt tgggtaaagc ccgcttccga tgaaatttgt
      661 aaaccctgcg ccgacaggct tgcgtaaaac tcttttggtg ataatgtgag ccttccaaat
      721 ccagactatt ccgatttggg atccattttg ccgtcctggc gtgtgtaacc gttttatcaa
      781 ggaataagca gtatgcgtaa aatcgcatta attcttgcga tgttgttgat cccgtgcgtt
      841 tcatttgccg gtttgctggg cagcagtagc tctaccacgc ctgtgagcaa agagtataag
      901 cagcagttga tgggatcccc tgtctacatc cagatcttca aggaagaacg tacgctcgat
      961 ctctacgtca aaatgggcga gcaatatcaa ctgctcgaca gctataaaat ctgtaaatat
     1021 tccggcggct tagggccaaa acagcgtcag ggcgatttca aaagcccgga agggttttat
     1081 agcgtccagc gtaatcagtt aaaaccagac agccgttact acaaagcgat taatattggt
     1141 ttccccaatg cctatgaccg tgcgcatggt tatgaaggga aatacctgat gatccacggc
     1201 gattgtgttt ccatcggctg ctacgcaatg accaatcagg gtattgatga gatattccag
     1261 ttcgttactg gtgcgctggt gtttggtcag ccgagcgtgc aagtgagtat ttacccgttc
     1321 cgcatgaccg acgccaatat gaagcgccat aaatattcca actttaagga cttctgggag
     1381 caactgaagc cgggttacga ctactttgag caaacccgta agccaccaac cgtttctgtg
     1441 gtcaatggtc gttacgtggt cagcaagccg ttaagccacg aagttgtgca gccacaactg
     1501 gcatcaaact acacgctccc cgaggcaaaa taagcgccat tcgcctggca taatcttttg
     1561 ccaggtttca ttgcccgtca gcggctgtgt tgcaatcacc gtgaccacat cattcggtgt
     1621 ggtctgcgag ctgaagtcga tttccacatc ctgatccagc aacgttgcca cgccaaacgg
     1681 cgcgcggcgg gtgatccagt gtaaattagt cgagcaatac gccattacat agcgcccgtc
     1741 cgaaagcagc atgttgaaaa cgcccttctg ccgcagttca tccgccagtg aggcgatata
     1801 tttaaatacc gccgccatgt tgcccggtgt gcgcgggtaa cgctgcgtta atttatgcag
     1861 gagccagcag aaggcttttt cgctgtcggt ttcgcctacc gggcggaagt tgccggtttc
     1921 cagtgatttg tagcccgtca gttgtccgtt atgggcataa gtccagttac gcccccataa
     1981 ctcgcgggta aatgggtgag tattttccag cgccacctcg ccccgattag cctggcgaat
     2041 atgagccacc accgaacagg attttatcgg gtagtcctgg acaagtttgg cgatggggga
     2101 attaaagctg ggttgtggat ctttaaatgt gcgacagcct ttaccttcgt aaaaggtaat
     2161 gccccagcca tctttatgtg gcccggttcc accaccacgc tgtacaagcc cggtgaaact
     2221 aaagcagata tcggtaggga cgttggcgct catcccgagc aattcgcaca tgggtaacct
     2281 ccacaacagc gggagcgcat ggcccccggc gaagattgat ttaagaattt tcaggtcgga
     2341 tgcggcgtga acgcattatt cggcctacgg ttcgcgtaca gatttgtagg catgataaga
     2401 cgcgtcagcg tcgcatcagg catcagcgca caaatgccgg atgcggcgta aacgtcttat
     2461 ccggcctacg ccagacttac ttaaccatct ctttttcaat caactggatc aggatatgga
     2521 tcactttaat gtgaatctcc tgaatgcggt cggcataacc aaagtgcggt acgcgaattt
     2581 cgatatccgc cgtgccagcc attttgccgc cgtctttacc ggtcagggtg atcactttca
     2641 ttcccttctc acgcgccgct gcgatcgctt tgatcacgtt tgcagagtta ccggaggtgg
     2701 agatccccag cagtacatcg ccttcgcgac ctaccgcttc aacgtagcgg gagaaaatat
     2761 cattgaaacc gaaatcatta ccgacgcagg aaatatgact aacgtcagaa atagcaatcg
     2821 ccgggtagcc cggacggttt tcacggtagc gaccggtcaa ctcttcggca aagtgcatag
     2881 cgtcgcaatg ggaaccgccg ttgccgcagg aaagcacttt gccaccggct ttaaagctgt
     2941 ctgctaacag gaccgccgcg cgctgaatgg cgtgaatatt ggcgtcatct tttaaaaagt
     3001 tagccagcgt ttccgccgct tcgttcagtt cgttacgaat aagatcctgg tacatgagga
     3061 tatccttcag cataaatgta atagacaaaa tgcagtgtac cggataccgc caaaagcgag
     3121 aagtacgggc aggtgctatg accaggactt tttgacctga agtgcggata aaaacagcaa
     3181 caatgtgagc tttgttgtaa ttatattgta aacatattgc taaatgtttt tacatccact
     3241 acaaccatat catcacaagt ggtcagacct cctacaagta aggggctttt cgttatgatg
     3301 attttgagta ttctcgctac ggttgtcctg ctcggcgcgt tgttctatca ccgcgtgagc
     3361 ttatttatca gcagtctgat tttgctcgcc tggacagccg ccctcggcgt tgctggtctg
     3421 tggtcggcgt gggtactggt gcctctggcc attatcctcg tgccatttaa ctttgcgcct
     3481 atgcgtaagt cgatgatttc cgcgccggta tttcgcggtt tccgtaaggt gatgccgccg
     3541 atgtcgcgca ctgagaaaga agcgattgat gcgggcacca cctggtggga gggcgacttg
     3601 ttccagggca agccggactg gaaaaagctg cataactatc cgcagccgcg cctgaccgcc
     3661 gaagagcaag cgtttctcga cggcccggta gaagaagcct gccggatggc gaatgatttc
     3721 cagatcaccc atgagctggc ggatctgccg ccggagttgt gggcgtacct taaagagcat
     3781 cgtttcttcg cgatgatcat caaaaaagag tacggcgggc tggagttctc ggcttatgcc
     3841 cagtctcgcg tgctgcaaaa actctccggc gtgagcggga tcctggcgat taccgtcggc
     3901 gtgccaaact cattaggccc gggcgaactg ttgcaacatt acggcactga cgagcagaaa
     3961 gatcactatc tgccgcgtct ggcgcgtggt caggagatcc cctgctttgc actgaccagc
     4021 ccggaagcgg gttccgatgc gggcgcgatt ccggacaccg ggattgtctg catgggcgaa
     4081 tggcagggcc agcaggtgct ggggatgcgt ctgacctgga acaaacgcta cattacgctg
     4141 gcaccgattg cgaccgtgct tgggctggcg tttaaactct ccgacccgga aaaattactc
     4201 ggcggtgcag aagatttagg cattacctgt gcgctgatcc caaccaccac gccgggcgtg
     4261 gaaattggtc gtcgccactt cccgctgaac gtaccgttcc agaacggacc gacgcgcggt
     4321 aaagatgtct tcgtgccgat cgattacatc atcggcgggc cgaaaatggc cgggcaaggc
     4381 tggcggatgc tggtggagtg cctctcggta ggccgcggca tcaccctgcc ttccaactca
     4441 accggcggcg tgaaatcggt agcgctggca accggcgcgt atgctcacat tcgccgtcag
     4501 ttcaaaatct ctattggtaa gatggaaggg attgaagagc cgctggcgcg tattgccggt
     4561 aatgcctacg tgatggatgc tgcggcatcg ctgattacct acggcattat gctcggcgaa
     4621 aaacctgccg tgctgtcggc tatcgttaag tatcactgta cccaccgcgg gcagcagtcg
     4681 attattgatg cgatggatat taccggcggt aaaggcatta tgctcgggca aagcaacttc
     4741 ctggcgcgtg cttatcaggg cgcaccgatt gccatcaccg ttgaaggggc taacattctg
     4801 acccgcagca tgatgatctt cggacaagga gcgattcgtt gccatccgta cgtgctggaa
     4861 gagatggaag cggcgaagaa caatgacgtc aacgcgttcg ataaactgtt gttcaaacat
     4921 atcggtcacg tcggtagcaa caaagttcgc agcttctggc tgggcctgac gcgcggttta
     4981 accagcagca cgccaaccgg cgatgccact aaacgctact atcagcacct gaaccgcctg
     5041 agcgccaacc tcgccctgct ttctgatgtc tcgatggcag tgctgggcgg cagcctgaaa
     5101 cgtcgcgagc gcatctcggc ccgtctgggg gatattttaa gccagctcta cctcgcctct
     5161 gccgtgctga agcgttatga cgacgaaggc cgtaatgaag ccgacctgcc gctggtgcac
     5221 tggggcgtac aagatgcgct gtatcaggct gaacaggcga tggatgattt actgcaaaac
     5281 ttcccgaacc gcgtggttgc cgggctgctg aatgtggtga tcttcccgac cggacgtcat
     5341 tatctggcac cttctgacaa gctggatcat aaagtggcga agattttaca agtgccgaac
     5401 gccacccgtt cccgcattgg tcgcggtcag tacctgacgc cgagcgagca taatccggtt
     5461 ggcttgctgg aagaggcgct ggtggatgtg attgccgccg acccaattca tcagcggatc
     5521 tgtaaagagc tgggtaaaaa cctgccgttt acccgtctgg atgaactggc gcacaacgcg
     5581 ctggtgaagg ggctgattga taaagatgaa gccgctattc tggtgaaagc tgaagaaagc
     5641 cgtctgcgca gtattaacgt tgatgacttt gatccggaag agctggcgac gaagccggta
     5701 aagttgccgg agaaagtgcg gaaagttgaa gccgcgtaaa tgaataacgg agccgaaagg
     5761 ctccgtttct ttatccgcta attatttaaa attaaagcca tccggatggt tttccaggct
     5821 gccggtcaac gccgcgaaca acaccgtttt accatcaatc gaaagcgcat cgttcacatt
     5881 cagccaagtg agtttctctt gcgacgtttt ctcatcaata gtcgagaaca gccccgtcat
     5941 ctgattagat ttctcggacc acatcacagc gatacgttgc gagccacagt catgcggttt
     6001 gcacgcgctc atcacctgat acgtctcatc tcccaacgtt acggtttgtg cgggagtata
     6061 agtaccgcct ttcatcaccc aggcaggcag cttatgccct tgtaccatct gattaaatgc
     6121 agctttggtg gtttcgccct ttgcaaggct gctaatggtt aaatcatcct gcgccattgc
     6181 actggtggcg atgaccagag cggcgactgt cgttattgcc ttaaacatca ttcctcccga
     6241 gcttatcctg cccatgttat taacctccta aagcctggcg ataacacgat aatttgcaaa
     6301 tcagatattt ccaatatcag catttgttat caatttattc tgcgctaagg caactgcctg
     6361 ataaggtgtt aaagttataa aacccttcgc ataaaggagt tgtacaccgt gcctggtttg
     6421 aagattacgc ttttgcagca accactggtg tggatggatg gtcctgccaa cctgcgtcat
     6481 tttgatcgtc aactggaagg tattaccggg cgcgatgtga tcgttctacc ggagatgttt
     6541 accagcggct ttgccatgga agcggcagct tcgtcgctag cacaagatga cgtagtgaac
     6601 tggatgacag ctaaggcgca gcagtgcaat gcgctgattg caggcagtgt tgcattacaa
     6661 acggagtctg gttcggttaa ccgctttttg ctggttgagc cgggcggcac ggtacatttt
     6721 tatgataagc gtcatctgtt ccgcatggca gatgagcatc tacattataa agcgggcaat
     6781 gcgcgagtga ttgtggaatg gcgcggctgg cgtattttgc cgctggtgtg ctacgactta
     6841 cgttttcctg tgtggtcgcg caatctcaac gattatgacc tcgccctgta cgtcgccaac
     6901 tggcctgctc cgcgctctct gcactggcag gcattgctga cggcccgcgc gattgagaat
     6961 caggcgtatg tggcgggatg caatcgcgtc ggcagcgatg gcaacggctg ccattatcgc
     7021 ggtgacagcc gggtgattaa tccgcaagga gagattatcg ctactgccga cgcgcatcag
     7081 gcaacgcgca ttgatgcgga gctgtcgatg gcagcattgc gggaatatag agaaaagttt
     7141 ccggcatggc aggatgcgga tgagtttagg ttgtggtgag tgggggttgt gtttaaggac
     7201 ggggagagtc ggggtattac tacgaaagcc cgctccccg
//
LOCUS       DACAOP010000158         7231 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.158, whole genome shotgun sequence.
ACCESSION   DACAOP010000158 DACAOP010000000
VERSION     DACAOP010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7231
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.158"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..951
                     /locus_tag="IT892_004234"
     CDS             <1..951
                     /locus_tag="IT892_004234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009483995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HAP3137366.1"
                     /translation="SDGPLGDDMDKNRAIAKRIGYPVIIKASGGGGGRGMRVVRGDAE
                     LAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADGQGNAIYLAERDCSMQRR
                     HQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFEFLFENGEFYFIEMNTRI
                     QVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHAVECRINAEDPNTFLPSP
                     GKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYGENRDVAIARMKNALQEL
                     IIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKKLGLQEK"
     gene            1060..1302
                     /locus_tag="IT892_004235"
     CDS             1060..1302
                     /locus_tag="IT892_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdT family protein"
                     /protein_id="HAP3137367.1"
                     /translation="MDTRFVQAHKEARWALGLTLLYLAVWLVAAYLSGVAPGFTGFPR
                     WFEMACILTPLLFIGLCWAMVKFIYRDIPLEDDDAA"
     gene            1292..2743
                     /gene="panF"
                     /locus_tag="IT892_004236"
     CDS             1292..2743
                     /gene="panF"
                     /locus_tag="IT892_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312157.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/pantothenate symporter"
                     /protein_id="HAP3137368.1"
                     /translation="MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMG
                     GIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILA
                     RRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYET
                     GLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQ
                     TIDPQLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIG
                     TIVVAILMFGMHLAGALGRAVIPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMS
                     TINAQLLQSSATIIKDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMI
                     IWLNLLAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFH
                     PIVPSLLLSLLAFLVGNRFGTSVPQATVLTTDK"
     gene            2755..3636
                     /gene="prmA"
                     /locus_tag="IT892_004237"
     CDS             2755..3636
                     /gene="prmA"
                     /locus_tag="IT892_004237"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAP3137369.1"
                     /translation="MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPL
                     PGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDN
                     FHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGK
                     TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQ
                     PEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFAL
                     DPVVEKEEWCRITGRKN"
     gene            3965..4930
                     /gene="dusB"
                     /locus_tag="IT892_004238"
     CDS             3965..4930
                     /gene="dusB"
                     /locus_tag="IT892_004238"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAP3137370.1"
                     /translation="MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSS
                     NPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMADAARINVESGAQIIDINMGCPA
                     KKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWAPEHRNCEEIAQLAED
                     CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPLKARAVLDYTGA
                     DALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCAHVRELHDFYGPAKGY
                     RIARKHVSWYLQEHAPNDQFRRTFNAIEDASEQLEALEAYFENFA"
     gene            4956..5252
                     /gene="fis"
                     /locus_tag="IT892_004239"
     CDS             4956..5252
                     /gene="fis"
                     /locus_tag="IT892_004239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator Fis"
                     /protein_id="HAP3137371.1"
                     /translation="MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNG
                     QDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN"
     gene            5338..6222
                     /gene="yhdJ"
                     /locus_tag="IT892_004240"
     CDS             5338..6222
                     /gene="yhdJ"
                     /locus_tag="IT892_004240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417728.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HAP3137372.1"
                     /translation="MRTGCEPTRFGNEAKTIIHGDALAELKKIPAESVDLIFADPPYN
                     IGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLF
                     TIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALI
                     DYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIV
                     LDPFAGSFTTGAVAIASGRKFIGIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTG
                     NLSKRSRLSEVDPDLITK"
     gene            6306..6485
                     /locus_tag="IT892_004241"
     CDS             6306..6485
                     /locus_tag="IT892_004241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2556 domain-containing protein"
                     /protein_id="HAP3137373.1"
                     /translation="MIRKYWWLVVFAVFVFLFDTLLMQWIELLATETDKCRNMNSVNP
                     LKLVNCDELNFQDRM"
     gene            complement(6488..7150)
                     /gene="acrS"
                     /locus_tag="IT892_004242"
     CDS             complement(6488..7150)
                     /gene="acrS"
                     /locus_tag="IT892_004242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrS"
                     /protein_id="HAP3137374.1"
                     /translation="MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVT
                     RGAIYWHFENKTQLFNEMWLQQPSLRELIQEHLTAGLEHDPFQQLREKLIVGLQYIAK
                     IPRQQALLKILYHKCEFNDEMLAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLD
                     VVMIIIDGAFSGIVQNWLMNMAGYDLYKQAPALVDNVLRMFMPDENITKLIHQTNELS
                     VM"
BASE COUNT         1771 a         1760 c         1865 g         1835 t
ORIGIN      
        1 tctgacggcc cgctgggcga cgatatggat aaaaaccgtg ccattgctaa acgcattggt
       61 tatccggtga ttatcaaagc ctccggcggc ggcggcggtc gcggtatgcg cgtagtgcgc
      121 ggcgacgctg aactggcaca atccatctcc atgacccgtg cggaagcgaa agctgctttc
      181 agcaacgata tggtttacat ggagaaatac ctggaaaatc ctcgccacgt cgagattcag
      241 gtactggctg acggtcaggg caacgctatc tatctggcgg aacgtgactg ctccatgcaa
      301 cgccgccacc agaaagtggt cgaagaagcg ccagcaccgg gcattacccc ggaactgcgt
      361 cgctacatcg gcgaacgttg cgctaaagcg tgtgttgata tcggctatcg cggtgcaggt
      421 actttcgagt tcctgttcga aaacggcgag ttctatttca tcgaaatgaa cacccgtatt
      481 caggtagaac acccggttac agaaatgatc accggcgttg acctgatcaa agaacagctg
      541 cgtatcgctg ccggtcaacc gctgtcgatc aagcaagaag aagttcacgt tcgcggccat
      601 gcggtggaat gtcgtatcaa cgccgaagat ccgaacacct tcctgccaag tccgggcaaa
      661 atcacccgtt tccacgcacc tggcggtttt ggcgtacgtt gggagtctca tatctacgcg
      721 ggctacaccg taccgccgta ctatgactca atgatcggta agctgatttg ctacggtgaa
      781 aaccgtgacg tggcgattgc ccgcatgaag aatgcgctgc aggagctgat catcgacggt
      841 atcaaaacca acgttgatct gcagatccgc atcatgaatg acgagaactt ccagcatggt
      901 ggcactaaca tccactatct ggagaaaaaa ctcggtcttc aggaaaaata agactgctaa
      961 agcgtcaaaa ggccggattt tccggccttt tttattactg gggatcgaca acccccataa
     1021 ggtacaatcc ccgctttctt cacccatcag ggacaaaaaa tggacactcg ttttgttcag
     1081 gcccataaag aggcgcgctg ggcgctgggg ctgacccttt tgtatctggc agtttggtta
     1141 gtagccgctt acttatctgg cgttgccccc ggttttaccg gctttccgcg ctggtttgag
     1201 atggcctgca tcctgacgcc gctgctgttt attggactgt gctgggcgat ggtgaaattt
     1261 atctatcgcg atatcccact ggaggatgac gatgcagctt gaagtaattc taccgctggt
     1321 cgcctatctg gtggtggtgt tcggtatctc ggtttatgcg atgcgtaaac ggagcaccgg
     1381 caccttcctt aatgagtatt tcctcggcag ccgctctatg ggcggtattg tgctggcgat
     1441 gacgctcacc gcgacctata tcagtgccag ttcgtttatc ggcgggccag gagctgctta
     1501 taaatacggg ctgggctggg tattgctggc gatgattcag cttcctgcag tctggctttc
     1561 actcggtatt ctcggcaaga agtttgcgat tcttgcgcgc cgctacaatg cagtgacgct
     1621 gaacgatatg ctgtttgccc gctaccagag tcgtcttctg gtgtggctgg cgagtttgag
     1681 tttgctggtt gcgttcgttg gtgcgatgac cgtgcagttt atcggcggtg cgcgcctgct
     1741 ggaaaccgcg gcgggtattc cttatgaaac cgggctgctg atttttggta tcagcattgc
     1801 gttatatacc gcctttggtg gctttcgcgc cagcgtgctg aacgacacca tgcaagggct
     1861 tgtgatgctg attggcaccg ttgtgctgct tattggcgta gtacatgccg ctggcggctt
     1921 aagtaacgca gtacagacct tgcaaaccat cgatccgcaa ctggttacgc cacaaggcgc
     1981 tgacgatatt ctgtcgcctg cctttatgac gtcgttctgg gtactggtgt gttttggcgt
     2041 gattggcctg ccgcatactg cggtgcgctg tatctcttat aaagacagca aagccgtaca
     2101 tcgggggatc atcatcggta cgattgtggt cgcaattctg atgttcggta tgcacctggc
     2161 cggagcgtta ggtcgggcgg tgatccccga tctcaccgta ccggacctgg tgatcccaac
     2221 gttaatggta aaagtgctgc caccgtttgc tgccgggatc ttcctggctg caccgatggc
     2281 tgcgatcatg tcgacaatta acgcccaact gctgcaaagt tccgctacga tcattaaaga
     2341 tctctatctg aatatccgtc cggatcaaat gcaaaacgag acgcgtctga agcggatgtc
     2401 ggcggtaatt acgttagttc tcggcgcgtt gctgctgctt gccgcctgga agccgccaga
     2461 aatgatcatc tggctgaatt tgttggcctt cggtgggctg gaagccgttt tcctgtggcc
     2521 gctggtgctg ggtctttact gggaacgcgc caacgccaaa ggcgcgctaa gtgcgatgat
     2581 cgttggcggc gtgctgtatg ccgtactcgc gacgctgaat attcagtacc tgggcttcca
     2641 ccctatcgtg ccctcgttac tactaagttt gctggctttc ctggtcggaa accgtttcgg
     2701 tacatccgtc ccgcaagcta ccgttttgac tactgataaa taaagagttt tgccatgcct
     2761 tggatccaac tgaaactgaa caccaccggc gcgaacgcgg aagatcttag cgatgcgctg
     2821 atggaagcgg gtgccgtttc tatcactttt caggataccc acgatacgcc agtatttgaa
     2881 ccgctgccgg gcgaaacgcg cctgtggggc gacaccgatg tgattggtct gttcgacgct
     2941 gaaaccgata tgaacgacgt ggtggcgatt ctggaaaacc atccgctgct cggcgcaggc
     3001 ttcgcgcata aaatcgaaca actagaagat aaagactggg agcgcgaatg gatggataat
     3061 ttccacccga tgcgctttgg tgaacgactg tggatctgcc ctagctggcg tgatgtgccg
     3121 gacgaaaacg ccgtcaacgt gatgttagat ccagggctgg cgtttggtac gggtacccat
     3181 ccaaccacct ctctgtgcct gcaatggctc gacagcctcg atttaaccgg taaaacagtc
     3241 atcgactttg gctgtggttc cggcattctg gcgatcgcgg cgctgaaact gggtgcagca
     3301 aaagccattg gtattgatat cgatccgcag gcgattcagg ccagccgcga taacgccgaa
     3361 cgtaatggcg tttctgaccg tctggaactc tacttaccga aagatcagcc agaagaaatg
     3421 aaagccgacg tggtggtcgc taacatcctt gcaggcccat tacgtgaact ggcaccgtta
     3481 atcagcgtcc tgccggtttc aggcggtttg ctgggccttt ccggtattct ggcaagccag
     3541 gcagagagcg tttgtgaagc ttatgccgat agcttcgcac tggacccggt cgtggaaaaa
     3601 gaagagtggt gccgtattac cggtcgtaag aattaacctt cgcatcgccg tagggtgacg
     3661 cggggcgaag tgcgagcaag ctcacaaaag gcacgtaaat ttgccgatta tttacgcaaa
     3721 tttgcgtgcc aaaattttca ttcataaaga aaaattgaga acttactcaa atttctttga
     3781 gtgtaaattt tagtcactat tttctaatat gatgattttt atgagtaatt atcgcaccac
     3841 gctcatttta aatgcaattc tttgatccat ctcagaggat tggtcaaagt ttggcctttc
     3901 atctcgtgca aaaaatgcgt aatatacgcc gccttgcagt cacagtatgg tcatttctta
     3961 actcatgcgc atcggacaat atcagctcag aaatcgcctg atcgcagcgc ccatggctgg
     4021 cattacagac agaccttttc ggacgttgtg ctacgagatg ggagccggat tgacagtatc
     4081 cgagatgatg tcttctaacc cacaggtttg ggaaagcgac aaatctcgtt tacggatggt
     4141 gcacattgat gaacccggta ttcgcaccgt gcaaattgct ggtagcgatc cgaaagaaat
     4201 ggcagatgca gcacgtatta acgtggaaag cggtgcccag attattgata tcaatatggg
     4261 ttgcccggct aaaaaagtga atcgcaagct cgcaggttca gccctcttgc agtacccgga
     4321 tgtcgttaaa tcgatcctta ccgaggtcgt caatgcagtg gacgttcctg ttaccctgaa
     4381 gattcgcacc ggctgggcac cggaacaccg taactgcgaa gagattgccc aactggctga
     4441 agactgtggc attcaggctc tgaccattca tggccgtaca cgcgcctgtt tgttcaatgg
     4501 agaagctgag tacgacagta ttcgggcagt taagcagaaa gtttccattc cggttatcgc
     4561 gaatggcgac attactgacc cgcttaaagc cagagctgtg ctcgactata caggggcgga
     4621 tgccctgatg ataggccgcg cagctcaggg aagaccctgg atctttcggg aaatccagca
     4681 ttatctggac actggggagt tgctgccccc gctgcctttg gcagaggtta agcgcttgct
     4741 ttgcgcgcac gttcgggaac tgcatgactt ttatggtccg gcaaaagggt accgaattgc
     4801 acgtaaacac gtttcctggt atctccagga acacgctcca aatgaccagt ttcggcgcac
     4861 attcaacgcc attgaggatg ccagcgaaca gctggaggcg ttggaggcat acttcgaaaa
     4921 ttttgcgtaa acagaaataa agagctgaca gaactatgtt cgaacaacgc gtaaattctg
     4981 acgtactgac cgtttctacc gttaactctc aggatcaggt aacccaaaaa cccctgcgtg
     5041 actcggttaa acaggcactg aagaactatt ttgctcaact gaatggtcag gatgtgaatg
     5101 acctctatga gctggtactg gctgaagtag aacagcccct gttggacatg gtgatgcaat
     5161 acacccgtgg taaccagacc cgtgctgcgc tgatgatggg catcaaccgt ggtacgctgc
     5221 gtaaaaaatt gaaaaaatac ggcatgaact aattcaggtt agctaaatgc ttgattaaaa
     5281 aggcgctact cggcatgggg aagcgccttt tttataggtg tcacaaaggg agtgaccatg
     5341 agaacaggat gtgaaccgac ccggtttggt aatgaagcta agaccattat tcacggtgat
     5401 gcgcttgccg aacttaaaaa gatccccgcc gaaagtgtcg atctgatctt tgccgaccca
     5461 ccatataaca tcggtaaaaa ttttgatggt ctgatcgaag cctggaaaga agatctgttt
     5521 atcgactggc tgtttgaagt gattgcagag tgccaccgcg ttctgaaaaa gcagggcagc
     5581 atgtacatca tgaacagtac ggaaaacatg ccctttatcg atctccagtg ccgcaagctt
     5641 tttaccatca aaagtcgcat cgtctggtca tatgacagtt ctggagtgca ggcgaaaaaa
     5701 cactacggct ccatgtacga acccatcctg atgatggtga aagacgcaaa gaactacaca
     5761 ttcaacggtg atgctattct ggtagaagcc aaaaccggat cgcagcgcgc gttgatcgat
     5821 tatcgcaaaa atcctccaca gccttacaat catcaaaaag taccgggtaa cgtttgggat
     5881 tttccgcgcg tgcgttattt gatggatgaa tatgaaaacc acccgacgca aaaaccggaa
     5941 gccttactga aacgcattat tctcgcctct tccaacccag gcgatatcgt tctcgacccg
     6001 tttgctggta gctttactac cggtgccgta gccatcgcca gcggacgaaa attcattggt
     6061 attgagatca acagcgagta catcaaaatg gggcttcgac ggctggatgt cgcgtcgcat
     6121 tactctgcgg aagaactggc gaaagtgaaa aaaagaaaga ccggcaacct gtcaaaacga
     6181 agccggttaa gcgaagttga ccccgatctc attacaaagt aaaggatgtg taagcctggt
     6241 tttcagatta ttcatttcgt gtatatttcc tgccagactt ggttaaacat gcacaggctc
     6301 aggtaatgat tcgcaagtat tggtggctcg tcgttttcgc tgtcttcgtt tttctgtttg
     6361 atactttact gatgcagtgg attgaactgc tggcaacaga aacagacaaa tgccgcaata
     6421 tgaactcagt taatccacta aaactggtta actgtgacga actgaatttt caggacagaa
     6481 tgtgaattta catgacactt aattcattcg tttgatgaat taatttcgtt atgttttcat
     6541 ctggcatgaa cattcttaat acgttatcga ccagagcggg ggcttgttta taaagatcat
     6601 aacccgccat attcattaac cagttttgaa caattccgct gaaggcacca tcaataataa
     6661 tcatcacaac atctaaatcg aggttatttg ctacacaacc ttgttgctga cacgcctgca
     6721 atacttcgcg gagagtctgc ggattaaagc ccatcttttc gcgtatcact ccctcggcca
     6781 gcatctcatc attaaattca catttgtgat ataagatttt cagcaacgcc tgctggcggg
     6841 gaattttggc aatatattgc aagccgacaa tcaatttttc acgcaattgt tgaaacgggt
     6901 catgctctaa tccagccgtc aagtgttcct ggattaactc ccgcaatgaa ggctgttgca
     6961 accacatctc attaaacagt tgagtcttgt tttcgaagtg ccagtagata gcgccacgcg
     7021 taacgttagc ggcgtcggca atgtcgttga gcgtcgtctt gcttacgcca tgctgcgcaa
     7081 actgggcgat ggcagtttca atcagttctt gccgggtctt cagagcttcg gctttggttc
     7141 tttttgccat gattaattat tcaggaaata aatatattcg acacagagtg agaaaatagc
     7201 gaaggttaat ctatcaccta atgtgtattt a
//
LOCUS       DACAOP010000159         7217 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.159, whole genome shotgun sequence.
ACCESSION   DACAOP010000159 DACAOP010000000
VERSION     DACAOP010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7217
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.159"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(126..1277)
                     /gene="argE"
                     /locus_tag="IT892_004243"
     CDS             complement(126..1277)
                     /gene="argE"
                     /locus_tag="IT892_004243"
                     /EC_number="3.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase"
                     /protein_id="HAP3137375.1"
                     /translation="MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFK
                     DLGFNVEVQPVPGTRNKFNMLASIGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHD
                     GKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTAL
                     RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQ
                     LRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNG
                     LLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEA
                     PFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH"
     gene            1431..2435
                     /gene="argC"
                     /locus_tag="IT892_004244"
     CDS             1431..2435
                     /gene="argC"
                     /locus_tag="IT892_004244"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HAP3137376.1"
                     /translation="MLNTLIVGASGYAGAELVTYVNRHPHMNITALTVSAQSNDAGKL
                     ISDLHPQLKGIVDLPLQPMSDISEFSPGVDVVFLATAHEVSHDLAPQFLEAGCVVFDL
                     SGAFRVNDATFYEKYYGFTHQYPELLEQAAYGLAEWCGNKLKEANLIAVPGCYPTAAQ
                     LALKPLIDADLLDLNQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEI
                     ATHLGADVIFTPHLGNFPRGILETITCRLKSGVTQAQVAQVLQQAYAHKPLVRLYDKG
                     VPALKNVVGLPFCDIGFAVQGEHLIIVATEDNLLKGAAAQAVQCANIRFGYAETQSLI
                     "
     gene            2443..3219
                     /gene="argB"
                     /locus_tag="IT892_004245"
     CDS             2443..3219
                     /gene="argB"
                     /locus_tag="IT892_004245"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418394.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HAP3137377.1"
                     /translation="MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGG
                     GCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGL
                     FLGDGDSVKVTQLDEELGHVGLAQLGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVN
                     ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKV
                     NAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA"
     gene            3280..4653
                     /gene="argH"
                     /locus_tag="IT892_004246"
     CDS             3280..4653
                     /gene="argH"
                     /locus_tag="IT892_004246"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HAP3137378.1"
                     /translation="MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKAL
                     VTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKK
                     LHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRA
                     QPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGF
                     ASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSG
                     SSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDT
                     WLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAV
                     VEAIRQGKPLEDLPLSELQKFSQVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIA
                     FAQARLG"
     gene            4920..5837
                     /gene="oxyR"
                     /locus_tag="IT892_004247"
     CDS             4920..5837
                     /gene="oxyR"
                     /locus_tag="IT892_004247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator OxyR"
                     /protein_id="HAP3137379.1"
                     /translation="MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELG
                     VMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVG
                     PYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPL
                     FDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTH
                     FRATSLETLRNMVAAGSGITLLPALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGS
                     PLRSRYEQLAEAIRARMDGHFDKVLKQAV"
     gene            complement(5820..>7217)
                     /gene="sthA"
                     /locus_tag="IT892_004248"
     CDS             complement(5820..>7217)
                     /gene="sthA"
                     /locus_tag="IT892_004248"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418397.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HAP3137380.1"
                     /translation="PHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGGC
                     THWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQG
                     FYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTHP
                     RIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQEM
                     SDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTDS
                     LALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALVK
                     GEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMNV
                     GTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTMA
                     EAYRVAALNGLNRLF"
BASE COUNT         1669 a         1781 c         2066 g         1701 t
ORIGIN      
        1 gttgggcatc gtttgagtca ctgtaggtcg gataagatgc gcaagcatcg catccgacat
       61 tattgcggca ctggagtttg gcaacagcgc cggatgcggc gcgagcgcct tatccggcct
      121 acgttttaat gccagcaaaa atggtgaatt acctgggtta tcagttcgcg ggtgggcttg
      181 ataaaccgtg tttccagata ttcatcaggt tgatgagcct gattaattga gccaggcccc
      241 aacaccagcg tcgggcataa cgtttgaata aacggcgctt cggtacagta gttcaccact
      301 tcggtttttg ctccgagcaa tttctcaacc acttcaacca gttgatgatt cggtgggcat
      361 tcatagccag ggatcggcgg atgcagctcg tcgaccgtca gacgacccgg ccagcgttcg
      421 ctcaccggag ccaatgcatc gttgagcaaa ccattaagtt cattgagtgt catgccaggc
      481 agcggacgaa tatccatatg caactcacag caagcgcaaa tacggttaga agcgtcgcca
      541 ccgtgaatat gcccgaggtt gagcgtaggg tatggcacgg taaacgcttc gtagtgataa
      601 cgttctttca ggttatcgcg caattgcaaa atatgcccga tggcgtcgtg cattagttcg
      661 atagcgttaa ctccgcgtgc tggatcgctg gagtgccccg actggccctg aatacggatg
      721 gcgttagaga tatgaccttt atgtgcgcgt accggttgta gtgacgtcgg ttcgccaatg
      781 atggcgcaat ccgggcgcag ggcggtagtt tcggcaaaat aacgcgctcc ggccatactg
      841 gtttcttcat cagcagtcgc cagaatgtag agcggttttt tcagtttcgt gacgtcgaca
      901 tcgcgtagcg catcaaggat aaacgcaaaa aagcctttca tgtcggcggt gcctaagccg
      961 taaagcttgc cgtcatgctc cgtcagtgta aacggatcgc gcgtccagcg accgtcatca
     1021 aatggcaccg tatcggtatg ccccgccagc aacaagccgc cagccccctg tccgatactt
     1081 gccagcatat tgaatttgtt gcgagttcct ggaacaggct gcacttccac attgaagccc
     1141 aaatctttaa accagtccgc cagcagagtg attaaatctg cattgctttg atcgagtgcc
     1201 tcttccgtgg cgcttattga aggtgtggca atcagagcgc ggtaaatctc gataaatggc
     1261 ggtaatttgt ttttcattgt tgacacacct ctggtcatga tagtatcaat attcatgcag
     1321 tatttatgaa taaaaataca ctaacgttga gcgtaataaa acccaccagc cgtaaggtga
     1381 atgttttacg tttaacctgg caaccagaca taagaaggtg aatagccccg atgttgaata
     1441 cgctgattgt gggtgccagc ggctacgctg gcgcagagct agtgacctat gtaaatcgcc
     1501 atccgcatat gaacataacc gctttgactg tttcagcgca aagcaatgat gcgggaaagt
     1561 taatctccga tttgcatccg cagctaaaag gcatcgttga tctgccgttg cagccgatgt
     1621 cggatatcag cgagtttagc ccaggggtgg acgtagtgtt tctcgccacc gcccatgaag
     1681 ttagccacga tttagcgccg cagtttcttg aagcgggctg cgtggtgttc gacctttccg
     1741 gcgcgtttcg tgttaacgac gccaccttct atgaaaaata ttacggcttt acccatcaat
     1801 acccggaact gttggaacag gcagcctacg gtctggcgga gtggtgcggt aataaattaa
     1861 aagaagcgaa tttgattgcg gtgccgggct gttatccgac ggcggcacag ctggcgctga
     1921 aaccgttgat tgatgccgat cttcttgacc tcaatcagtg gccggtgatc aacgccacca
     1981 gcggcgtgag cggtgcaggg cgtaaagcgg ccatttcaaa cagcttttgt gaagttagcc
     2041 tgcaaccgta tggcgtcttt actcatcgcc atcaaccaga gatcgccaca cacctcggtg
     2101 ctgacgttat cttcacccca catctgggca atttcccgcg cggcattctc gaaaccatta
     2161 cctgccgcct gaaatcgggt gtgacccagg cgcaagtcgc gcaagtgtta cagcaggcgt
     2221 atgcccataa accgctggtg cggctgtatg acaaaggcgt tccggcgctg aaaaatgtcg
     2281 ttgggctgcc attttgcgat atcgggtttg ccgttcaggg cgagcatctg attattgtgg
     2341 cgaccgaaga caacttactg aaaggcgcgg cggcacaagc ggtacagtgc gccaatattc
     2401 gtttcggcta tgcggaaacg cagtctctta tttaagggtg caatgatgaa tccattaatt
     2461 atcaaactgg gcggcgtact gctggatagt gaagaggcgc tggaacgtct gtttagcgca
     2521 ctggtgaatt atcgtgagtc acatcagcgt ccgctggtga ttgtgcacgg cggcggttgc
     2581 gtggtggatg agctgatgaa agggctgaat ctgccggtga aaaagaaaaa cggcctgcgg
     2641 gtgacgcctg ctgatcagat agacattatc accggagcac tggcgggaac ggcaaataaa
     2701 accctgttgg catgggcgaa gaaacatcag attgcggccg taggtttgtt tctcggtgac
     2761 ggcgacagcg tcaaagtgac ccagcttgat gaagagttag gtcatgttgg actggcgcag
     2821 ctaggttcgc ctaagcttat caactccttg ctggagaacg gttatctgcc ggtggtcagc
     2881 tccattggcg taacagacga agggcaactg atgaacgtca atgccgacca ggcggcaacg
     2941 gcgctggcgg caacgctggg cgcggatctg attttgctct ccgacgtcag cggcattctc
     3001 gacggcaaag ggcaacgcat tgccgaaatg accgccgcga aagcagaaca actgattgag
     3061 cagggcatta ttactgacgg catgatagtg aaagtgaacg cggcgctgga tgcggcccgc
     3121 acgctgggcc gtccggtaga tatcgcctcc tggcgtcatg cggagcagct tccggcactg
     3181 tttaacggta tgccgatggg tacgcggatt ttagcttaag ttttgttggc cggaggcgca
     3241 gctttccggc attgaatttc aaaataagga aacagagtta tggcactttg gggcgggcgt
     3301 tttacccagg cagcagatca acggttcaaa caattcaacg actcactgcg ctttgattac
     3361 cgtctggcgg agcaggatat tgttggctct gtggcctggt ccaaagccct ggtcacggta
     3421 ggcgtgttaa ccgcagaaga gcaggcgcaa ctggaagagg cgctgaacgt gttgctggaa
     3481 gatgttcgcg ccaggccaca acaaatcctt gaaagcgacg ccgaagatat ccatagctgg
     3541 gtggaaggca aactgatcga caaagtgggc cagttaggca aaaagctgca taccgggcgt
     3601 agccgtaatg atcaggtagc gactgacctg aaactgtggt gcaaagatac cgttagcgag
     3661 ttactgacgg ctaaccggca gctgcaatcg gcgctggtgg aaaccgcaca aaacaatcag
     3721 gacgcggtaa tgccaggtta cactcacctg caacgcgccc agccggtgac gttcgcgcac
     3781 tggtgcctgg cctatgttga gatgctggcg cgtgatgaaa gccgtttgca ggatgcgctt
     3841 aagcgtctgg atgtcagccc gctaggctgt ggcgcgctgg cgggaacggc ctatgaaatc
     3901 gaccgtgaac agttagcagg ctggctgggc tttgcttcgg cgacccgtaa cagtctcgac
     3961 agcgtttctg accgtgacca tgtgttggaa ctgctttctg ctgccgctat cggcatggtg
     4021 catctgtcgc gttttgctga agatctgatt ttctttaaca ccggcgaagc ggggtttgtg
     4081 gagctttctg accgcgtgac ttccggttca tcattaatgc cgcagaagaa aaacccggat
     4141 gcgctggagc tgattcgcgg taaatgcggc cgggtgcagg gggcgttaac cggcatgatg
     4201 atgacgctga aaggtttgcc gctggcttac aacaaagata tgcaggaaga caaagaaggt
     4261 ctgttcgacg cgctcgatac ctggctggac tgcctgcata tggcggcgct ggtgctggac
     4321 ggcattcagg tgaaacgtcc acgttgccag gaagcggctc agcagggtta cgccaacgcc
     4381 accgaactgg cggattatct ggtggcgaaa ggcgtaccgt tccgcgaggc gcaccatatt
     4441 gttggtgaag cggtggtgga agccattcgt cagggcaaac cgctggaaga tctgccgctc
     4501 agtgagttgc agaaattcag tcaggtgatt gacgaagatg tctatccgat tctgtcgctg
     4561 caatcgtgcc tcgacaagcg tgcggcaaaa ggcggcgtct caccgcagca ggtggcgcag
     4621 gcgattgctt ttgcgcaggc tcggttaggg taagaacatt tatatgtata aatttgagcc
     4681 tggcttatcg ccgggctttt ttatggcaaa aaaaagcgga tcctggagat ccgcaaaagt
     4741 tcacgttggc tttagttatt cgagttgaga aactctcgaa acgggcagtg acttcaaggg
     4801 ttaaaagagg tgccgctccg tttctgtgag caattatcag tcagaatgct tgatagggat
     4861 aatcgttcat tgctattcta cctatcgcca tgaactatcg tggcgatgga ggatggataa
     4921 tgaatattcg tgatcttgag tacctggtgg cattggctga acaccgccat tttcggcgtg
     4981 cggcagattc ctgccacgtt agccagccga cgcttagcgg gcaaattcgt aagctggaag
     5041 atgagctggg cgtgatgttg ctggagcgga ccagccgtaa agtgttgttc acccaggcgg
     5101 gaatgctgct ggtggatcag gcgcgtaccg tgctgcgtga ggtgaaagtc cttaaagaga
     5161 tggcaagcca gcagggcgag acgatgtccg gaccgctgca cattggtttg attcccacag
     5221 ttggaccgta cctgctaccg catattatcc ctatgctgca ccagaccttt ccaaagctgg
     5281 aaatgtatct gcatgaagca cagacccacc agttactggc gcaactggac agcggcaaac
     5341 tcgattgcgt gatcctcgcg ctggtgaaag agagcgaagc attcattgaa gtgccgttgt
     5401 ttgatgagcc aatgttgctg gctatctatg aagatcaccc gtgggcgaac cgcgaatgcg
     5461 taccgatggc cgatctggca ggggaaaaac tgctgatgct ggaagatggt cactgtttgc
     5521 gcgatcaggc aatgggtttc tgttttgaag ccggggcgga tgaagataca cacttccgcg
     5581 cgaccagcct ggaaactctg cgcaacatgg tggcggcagg tagcgggatc actttactgc
     5641 cagcgctggc tgtgccgccg gagcgcaaac gcgatggggt tgtttatctg ccgtgcatta
     5701 agccggaacc acgccgcact attggcctgg tttatcgtcc tggctcaccg ctgcgcagcc
     5761 gctatgagca gctggcagag gccatccgcg caagaatgga tggccatttc gataaagttt
     5821 taaaacaggc ggtttaaacc gtttaacgca gctacccgat aggcttccgc catcgtcggg
     5881 tagttaaagg tggtgttgac gaagtactca atagtgttgc cgccaccttt ctgttccata
     5941 atcgcctgac cgatatgaat aatttcggca gcgcgctcgc caaagcagtg aatacccaga
     6001 atctcttttg tttcccgatg gaacaaaatt ttcagcgtgc ccacgttcat gccgacgatt
     6061 tgtgcgcgtg ccagatgttt aaactgggcg cggcccactt catatggcac tttcattgcg
     6121 gtcagctgct gttcggtttt gcccacagag ctgatttccg ggatggtgta aataccggta
     6181 gggatatctt caatcagatg tgcggtggct tcgcctttta ccagcgcctg cgcggcaatg
     6241 cgcccctggt cataggccgc cgacgccagg ctcggataac caatcacgtc gcccaccgcg
     6301 taaacgtgtg gctgtgcggt ctgatacatg ctgttgacct tcagctgtcc gcggctgtca
     6361 gtttctagcc caatgttctg taacgccagc gaatcggtat taccggtgcg accgttggca
     6421 tagagcaggc agtcagcttt cagtttttta cccgacttca gatgcatgat cacaccatcg
     6481 tcacagcctt cgatcttctc gtactcttcg ttgtgacgaa tcactacgcc actgttccag
     6541 aagtgatagg agagagaatc tgacatctct tgatcgagaa atgccagcag gcgatcgcgg
     6601 gtgttgatca gatccacttt tacatccata ccgcggaaga tcgacgcata ttcacagccg
     6661 atcactccag caccatagat aagtacatgg cgcggttcgt ggtgcatgct gagaattgag
     6721 tcgctgtcgt aaatgcgtgg atgggtgaaa tcaacatctg ttggatgata tggacgagag
     6781 ccgcaggcaa taacaaattt ttcagcggtt agtgtttcaa cgctgccgtc cgggcaatcc
     6841 agcgccaacg tatgctcgtc aacaaagcga gcgtttccct gcaatatttc acagtgatta
     6901 cgttcgtaaa atccctgacg catgcgcgtt tgttgattaa tcacgttatc ggcatggtta
     6961 aggatatcgg caaaagaaga gcggagcagt cgggaatggt cgctgtaaag tgggttttga
     7021 ttgaattcta taatgcggct gacggcgtga cggagagctt tcgacgggat ggtgccccag
     7081 tgggtgcaac cgccgccaac attttgataa cgctcgataa ctgcgacgcg cgcaccttgc
     7141 ttaaccaggc ccattgcagc gccttcgccg ccggggccgg aacctattac tatggcatcg
     7201 taatcgtagg aatgtgg
//
LOCUS       DACAOP010000160         7062 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.160, whole genome shotgun sequence.
ACCESSION   DACAOP010000160 DACAOP010000000
VERSION     DACAOP010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7062
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.160"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(349..1159)
                     /locus_tag="IT892_004249"
                     /pseudo
     CDS             complement(349..1159)
                     /locus_tag="IT892_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001380078.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
     gene            1945..2922
                     /locus_tag="IT892_004250"
     CDS             1945..2922
                     /locus_tag="IT892_004250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP3137381.1"
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNT
                     LSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVE
                     LPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSA
                     YYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPA
                     PISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKLFCIHYRRPR
                     LKAPNDESKENPLPPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR"
     gene            complement(3207..3947)
                     /locus_tag="IT892_004251"
     CDS             complement(3207..3947)
                     /locus_tag="IT892_004251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP3137382.1"
                     /translation="MNNVILLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAY
                     LLAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLDGVRPFVRILSEK
                     VRARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAV
                     RRAEADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFAL
                     DMAATLAVPFTGDGRDAAEILRTLPPLR"
     gene            complement(4068..4193)
                     /locus_tag="IT892_004252"
     CDS             complement(4068..4193)
                     /locus_tag="IT892_004252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001460400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP3137383.1"
                     /translation="MPWHYPISPKNRKTALSPRHDWLKTGSLLQNVPLRIWFYPQ"
     gene            complement(4593..4900)
                     /locus_tag="IT892_004253"
                     /pseudo
     CDS             complement(4593..4900)
                     /locus_tag="IT892_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461876.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
     gene            5393..6562
                     /locus_tag="IT892_004254"
     CDS             5393..6562
                     /locus_tag="IT892_004254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137384.1"
                     /translation="MNQKWKTLIISLLTPSSIISGIALIVLWGYFSRLGRLDIFFDVM
                     NIKSILVLVCCATILSLAMIVFIFFITSFFIPVVIPQDINNLPAYNKIQGNFLSVMML
                     SGMFPMAFIYVLYCAFDFDQNVKDNSGWLSIASMGVLIAVILAIVNKRYLEYDLSFKN
                     NRMKLLRRVQIYLVIPLSIALLVHLQLIPLEIVFSNIATSDKSVNFKVIAELAFMSYF
                     IFLLTMLPGVIYLKMNPQHKFSKRISYSFIASLMLLLIISTQITVLPVIFTHSVIKLS
                     GISDFKIHSYIIKTSEYPEEFFSNAAWDKKNIKPGDYYSVQAVSMFTTNQFILLCPKD
                     IIKFYRESWKFELLNVDFDINTRKKLQEEAAYCVPISAISVKRWDMPLQGSKPSS"
     gene            6595..6723
                     /locus_tag="IT892_004255"
                     /pseudo
     CDS             6595..6723
                     /locus_tag="IT892_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014543172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6758..7051)
                     /locus_tag="IT892_004256"
     CDS             complement(6758..7051)
                     /locus_tag="IT892_004256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137385.1"
                     /translation="MNYDEITKITAERISDYMTEAVNTDSIAVAEMFHNAAWGARTLW
                     FELVTKIDIDIHKKNRYASYDLRRKIEMQHEEFQKMTEREQVPLLKCISSDLI"
BASE COUNT         1864 a         1636 c         1601 g         1961 t
ORIGIN      
        1 gcccgttttg ccataaatct ggttcgttcc atcatgactt atgttgatga gttgctttag
       61 ttttaataaa aatatgagac tcacagcgaa cagatagaac ttcaacgaag aagtgaagta
      121 cggccagaat ttcgagctct ggccctccgg aagatgccgg acagacgcat catcccgtcg
      181 tggccgcttc catttttgtg tgtactcaac ctgccggatc aggatggcgg caggatttgc
      241 acccgatgtt ccagccgcct tgcctcttcc tgatcccggt attccctcgc ctttttcatc
      301 atttctgccg ttggctcctg cagtttgtcg agaaactcct tagatcgttt agccaccgac
      361 tgaagggaga cactgtccgt cctgccggta ttgcgattgg tgtaaaccag gcgggtaagg
      421 gggtctggtt aactccttcc cttccataaa gcgtttgaag atccagagat atatatcaac
      481 cagctccagc cctgcacttt ttgtacccga ctggaaaacc agcgttcagc cggcatgttc
      541 gtcacatcca tgaccggtaa accgggaccg tgtacccacg gcatctcacg tatctggtaa
      601 tagaactccc tcagctcccg ctgggtggtg ttgaactgtg actgctggtc cacaacgatg
      661 tcggctttgc gatttggtgc tcccaggcgg gaacagatac cgcgcaatac gaactgaaat
      721 ccaaccatat tgggcatgat ctgcagcttt tgtttaccgg ttttgcagtt atatcccagt
      781 tcgtcaaagt gggtcatcgc ccaggacaac gcatcggtaa tcaattcaat gtaacggcgg
      841 tcccccaggg tatgaacgcg cgcaagcagc tcactgcaga cctcactgaa cagagatgag
      901 gaccttccat catgggcttc gaggcgggca caccacgctt tttcagccag ttcattatcg
      961 aacaggcttg ccagattcag tagcagcggg taacgaaagg ggtccagtag gcaaccctgg
     1021 gcactgcagg attcatcccc tgatcgaaga acgaaataat ggcgtgatcc cgtttaacga
     1081 cctgccagac atcaaaccgt atccggtgct tcttctgcag gacaagcagc gtatcaacca
     1141 cctcatcaag gcggtgcatg ccaagctctg cggcgtgcag acgctgtact tgtcaacgcc
     1201 acgatctttg accgtcttat atcgacagag ttatccggca tggtgtcaat ccgttcacaa
     1261 tttttccatc ggagcagcct accaccggtg ataaccagac tttgcctgta gtttgtatac
     1321 acaatccctg gcattgaaac acacatatga agtgtacttc ggatatgacc gtacgctcag
     1381 gaagtacggc agattccgtc aaaaattacc tgtaaagaca gacatcagaa aaacagtgct
     1441 cgccgcagac cggtgaccgg gcgaagcccg cgaaccggcg aggaagcgca atggatctgt
     1501 agttacagtg agcaggtacg ccctgaagcc ttcataatcg gtagtgtatg ctgtttttct
     1561 ggaatgattt atccacatat ccggaggccc gatccagtaa acagatccat gaatgatcaa
     1621 caaaggatcc attaaagatc cccatatctc tgcaaacctt gtcactcatg ggccgggact
     1681 acgatcacat aagctgtggc atgttactga taaactgtaa catgctaatg ataagctgta
     1741 ttcagtaatc catatactga agtaagttaa tgacataaac tatggtcagt atgccagact
     1801 cagttgttaa atacaggctg caggtttttc ttcagtcagt tagcggagtt ctgacacacg
     1861 attttctgtt tattctttta ctgtccacag gctggaggct ttctggaaaa cgaaaattca
     1921 gacatcaaaa aactgttcgg cgaggtggat aagtcgtccg gtgagctggt gacactgaca
     1981 ccaaacaata acaacaccgt acaacctgtg gcgctgatgc gtctgggcgt ctttgtaccg
     2041 acccttaagt cactgaagaa cagtaaaaaa aatacactgt cacgcaccga tgccacggaa
     2101 gaactgacgc gtctttctct ggcccgtgca gaaggattcg ataaggttga gatcaccggc
     2161 ccccggctgg atatggataa cgatttcaag acctgggtgg ggatcattca ttcctttgcc
     2221 cgccataacg tgattggtga caaagttgaa ctgccttttg ttgagtttgc aaaactgtgt
     2281 ggtatacctt caagccagtc atcccgcagg ctgcgtgagc gcatcagccc ttccctgaag
     2341 cgcattgccg gtaccgtgat ctcgttttcc cgtaccgatg agaagcacac ccgggaatac
     2401 atcacccatc tggtacagtc agcctactac gatactgaac gggatattgt tcagttacag
     2461 gctgatcccc gcctgtttga actgtaccag tttgacagaa aggtccttct tcagcttaag
     2521 gcgattaatg ccctgaagcg acgggagtcc gcccaggcac tctacacctt tatagagagc
     2581 ctgccccggg atccggcacc gatatcgctg gcgcggctgc gtgcacgcct caatctgaag
     2641 tctcctgtat tttcccagaa ccagacggtc agacgggcaa tggagcagct gcgcgagatt
     2701 ggatatcttg attacacgga gatccagcgg gggcggacaa aactcttctg cattcactac
     2761 cggcgtcccc ggttaaaagc gccgaatgat gagagtaagg aaaatccgtt gccaccttca
     2821 cctgcggaaa aagtcagtcc ggagatggcg gagaaacttg ccctgcttga aaaactgggc
     2881 atcacgctgg atgacctgga aaaactcttc aaatcccgct gaacataaac tgtagtcagt
     2941 gaagagcgct cctttactga ctacagctta tattaaccgg tgcagtgagt ggtctgctca
     3001 ctgcagttta tattctgttt cctgcagtgc tgtctgtagc tgagctgcca tctgcctgtc
     3061 ccttacgtaa gtgatcccgt aacctgatgc tgaggcattg ctcccttcat aaaacatgac
     3121 ttactcacta cagcttatat acatactcca gcttatgtta tgtctgttct gctgaccaca
     3181 gcttatataa ggaagcgcgt atgccgtcac ctcaggggag gcagtgtacg caggatctcc
     3241 gcagcatccc gcccgtcacc ggtgaaaggc actgccagcg tggcagccat atccagtgca
     3301 aacactctgg tataaacctc catcgaacgt ggatccctgt gaccagccag tgcctggatg
     3361 actttccggg gctggcggtg atagagcatg tgcatgatat agctgtgccg gaaggtgtgt
     3421 ggtgtgaccg gaatcgaaaa gtgtaccccg tcagcttcgg cccgtctgac agcctgcttc
     3481 agccagttgc gcatggtttc gtcggtcacg gcccataatg gttcacgacg acggggccgg
     3541 gtggtgatca tccagctttc catctgcctg acatagctta tatctgtcag cggaaccagg
     3601 cgcacttcat cttttggcgg gcgtccgcgt cgcgcacgca ctttttcgga caggatccgc
     3661 acaaacggtc ttactccatc caggtcaaat gattccggtg tcagcatccg ggcttcgcca
     3721 atacgcattc cggtattcca gagggtggcg aacagcatat ggtgacgctg atccggcata
     3781 tagaaaagaa gggcactcac ttccggggcc agcaggtagg ccggtgtggc ccccgtggaa
     3841 gtggccattc ttctcaggga gagcgctgtt gcaaaatcca cccccggcgc aatgggtaac
     3901 agggagacgc gttctggtga attctgcagg agaatgacat tgttcatgag ttatttttca
     3961 cgtagcacac gcactgttta tggatacagg tattctgacc tgaacgcccg gatccttcca
     4021 cgacaataaa tcgcagcgcg cggatccttt tgtttgctta tcacgcatta ttgcgggtaa
     4081 aaccaaatac gtaaaggtac gttttgcagc agggatcccg tcttaagcca gtcgtggcgc
     4141 gggctgaggg ctgttttacg gtttttggga gaaatggggt aatgccaggg caaagatgat
     4201 cgcaaggaaa ggagaaaaat acacagagag gggagttgcg ctacgtgaat tctggctagg
     4261 tacacccctg taaccctgcc agttttcacg caacgcaatg tggtggctga ttactgtcag
     4321 ttgaaatgac ggctggcatc ctgatgctga cttaatatac gaataataac aatttcagta
     4381 tcagtctgca gaaaataaac catatgccgt tcaacgggta gtgcgaatgt gtattcccca
     4441 gttcaggagg gggagtaccg atattatgat tactcataac ctgaaaaatg tcggatatct
     4501 gattaatata tttatcagcc tactcttcac cgaaatggtg gtacccgtaa tgctagatat
     4561 cctccagatc ctgactggct ttaggtgtga gtttaacggt tttcaccgga agccctcgcg
     4621 ccagctttca cttttttcag aaacgcattt ttttcccacg acacaggttc accgctgctc
     4681 aagccttctg ccagtaaatc ccgcaggaca cctggagacg tgactctgcc tgtttctctc
     4741 gaaggagacg aagtgactcg cggattacct cactctgtgt acgataatca cctgattcta
     4801 tgagagattc tatgtactcc cagagttcat ctccgagagc aactgtcatt gttctggcca
     4861 tatcaagcct cgtgattgta agtttaaatt ttacatgcag tttattcgat actcaaaggt
     4921 gcttccagta cagaacattt gggagaattg gggtaatgcc tggaacagac agatacggag
     4981 aaaaaccctg cagataacct tatacgacaa ctgaaggtgt ctgatgccat attcttagct
     5041 acttctctgt cttcaggcgg cttagtcaca acataagacc gatgcataat aagcatattt
     5101 tttcatgtta tggtcttgtt catgcatgaa ctattatcta ttcagtcact tttaaagttt
     5161 tatatcatac tgcatatgat atatatcatc tcctatattc agactaaaaa tattatgacg
     5221 atggtcaaat gaatttagtg aaaacgctac ctaaaacaat atgcttatga tataacttat
     5281 caagaatatg cgacaatctt cttgaaaggt tacggagaag agtcagataa tgaagtgtta
     5341 taactcattc agctttttta tgttctcttt atagtaaaac caggagatta agatgaatca
     5401 gaagtggaag acgttaatta tttcattatt aacaccatca agtattatat cagggattgc
     5461 gttgatagtt ctctggggat atttcagtcg cctgggccga ctagatattt tctttgatgt
     5521 aatgaatatt aaaagcatct tggtattggt ttgttgtgca actatactat cattggctat
     5581 gatagtattt atctttttta taacctcttt ttttataccc gtagttattc ctcaggatat
     5641 aaataatctt cctgcttaca ataagattca gggtaatttt ttatctgtga tgatgttatc
     5701 tggcatgttc cccatggcct ttatatatgt gttatactgt gcatttgatt ttgatcagaa
     5761 tgttaaagat aactctggct ggttatctat tgcaagtatg ggtgtactga tagctgttat
     5821 tttagccata gtaaataaga ggtatcttga atatgactta tcgtttaaaa acaatagaat
     5881 gaaactgttg agacgtgttc agatctatct tgtcattccg ttgtctattg ctttactggt
     5941 gcatcttcag ttaattcctc tggagatagt ttttagtaat attgcaactt cagataagag
     6001 tgttaatttc aaagtgatag ctgaactggc tttcatgtca tattttatct ttcttctgac
     6061 aatgcttcct ggagtcattt atctgaaaat gaatccacag cataaatttt caaaaagaat
     6121 tagctattca tttatcgcat ccttgatgtt attattaata atatcgactc aaataaccgt
     6181 gttaccagtg atttttaccc attccgttat taagctatca ggtataagtg acttcaaaat
     6241 acatagctac attattaaaa caagtgaata tcctgaagag tttttttcca atgcagcatg
     6301 ggataaaaaa aatataaaac cgggggatta ttactctgtg caggctgttt ctatgtttac
     6361 gacaaaccag tttattctcc tttgtcctaa ggatattata aagttttatc gggaaagctg
     6421 gaagttcgag ttgcttaatg tagacttcga tataaatacc aggaagaaac tccaggaaga
     6481 agctgcatat tgcgtaccaa tttctgcaat atctgtaaaa cgatgggata tgcctcttca
     6541 gggctcgaaa ccctcaagtt agaaggcaac tagggcgact gtattctgtg acgaaatgaa
     6601 tggctggctc actataataa tgagcgaacc catcagggaa aaatgtgcaa tgggcggacg
     6661 ccaatggaaa cgttactcga tggaaaacgc atctgggccg agaaaaattt aagccagatg
     6721 taatctgaca gatacctgta taaataaccg ataactgtca gatcaggtct gagctaatac
     6781 atttcaataa aggtacttgc tcgcgctctg tcattttctg aaactcttca tgctgcattt
     6841 cgattttcct tctaagatca taactcgcat acctgttctt tttatgtata tctatatcta
     6901 tttttgtgac gagttcaaac cacaatgttc gcgctcccca tgcagcgtta tgaaacattt
     6961 ccgcaacggc tatagagtct gtattaactg cttcagtcat gtagtcgcta atacgttcag
     7021 cggtaatttt cgttatttca tcgtaattca ttttatctcc ta
//
LOCUS       DACAOP010000161         7026 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.161, whole genome shotgun sequence.
ACCESSION   DACAOP010000161 DACAOP010000000
VERSION     DACAOP010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7026
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.161"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..630
                     /gene="folP"
                     /locus_tag="IT892_004257"
     CDS             <1..630
                     /gene="folP"
                     /locus_tag="IT892_004257"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HAP3137386.1"
                     /translation="ALSDQMHRVSIDSFQPETQRYALKRGVGYLNDIQGFPDPALYPD
                     IAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSALRRSGVAADRLIL
                     DPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGATVGLPVKDLGPAS
                     LAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGLDHA"
     gene            758..1258
                     /locus_tag="IT892_004258"
     CDS             758..1258
                     /locus_tag="IT892_004258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP3137387.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARI
                     DRTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHA
                     GRGVSSALIEACRHAARTQGCAKLRLDCHPNLRGLYERLGFTHVDTFNPGWDPTFIAE
                     RLELEI"
     gene            complement(1717..2499)
                     /locus_tag="IT892_004259"
     CDS             complement(1717..2499)
                     /locus_tag="IT892_004259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004630242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP3137388.1"
                     /translation="MQHEGHVRILKSLKLFGMAHAIEELGNQNSPAFNQALPMLDSLI
                     KAEVAEREVRSVNYQLRVAKFPVYRDLVGFDFSQSLVNEATVKQLHRCDFMEQAQNVV
                     LIGGPGTGKTHLATAIGTQAVMHLNRRVRFFSTVDLVNALEQEKSSGRQGQIANRLLY
                     ADLVILDELGYLPFSQTGGALLFHLLSKLYEKTSVILTTNLSFSEWSRVFGDEKMTTA
                     LLDRLTHHCHILETGNESYRFKHSSTQNKQEEKQTRKLKIET"
     gene            complement(2489..4012)
                     /locus_tag="IT892_004260"
     CDS             complement(2489..4012)
                     /locus_tag="IT892_004260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001324342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS1326 family transposase"
                     /protein_id="HAP3137389.1"
                     /translation="MINVAILSAIRRWHFRDGASIREIARRSGLSRNTVRKYLQSKVV
                     EPQYPARDSVGKLSPFEPKLRQWLSTEHKKTKKLRRNLRSMYRDLVALGFTGSYDRVC
                     AFARQWKDSEQFKAQTSGKGCFIPLRFACGEAFQFDWSEDFARIAGKQVKLQIAQFKL
                     AHSRAFVLRAYYQQKHEMLFDAHWHAFQIFGGIPKRGIYDNMKTAVDSVGRGKERRVN
                     QRFTAMVSHYLFDAQFCNPASGWEKGQIEKNVQDSRQRLWQGAPDFQSLADLNVWLEH
                     RCKALWSELRHPELDQTVQEAFADEQGELMALPNAFDAFVEQTKRVTSTCLVHHEGNR
                     YSVPASYANRAISLRIYADKLVMAAEGQHIAEHPRLFGSGHARRGHTQYDWHHYLSVL
                     QKKPGALRNGAPFAELPPAFKKLQSILLQRPGGDRDMVEILALVLHHDEGAVLSAVEL
                     ALECGKPSKEHVLNLLGRLTEEPPPKPIPIPKGLRLTLEPQANVNRYDSLRRAHDAA"
     gene            4135..5679
                     /locus_tag="IT892_004261"
                     /pseudo
     CDS             4135..5679
                     /locus_tag="IT892_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1353 family transposase"
     gene            complement(5730..6590)
                     /locus_tag="IT892_004262"
     CDS             complement(5730..6590)
                     /locus_tag="IT892_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP3137390.1"
                     /translation="MDEYPIIDLSHLLPAAQGLARLPADERIQRLRADRWIGYPRAVE
                     ALNRLEALYAWPNKQRMPNLLLVGPTNNGKSMIVEKFRRTHPASSDADQEHIPVLVVQ
                     MPSEPSVIRFYVALLAAMGAPLRPRPRLPEMEQLALALLRKVGVRMLVIDELHNVLAG
                     NSVNRREFLNLLRFLGNELRIPLVGVGTRDAYLAIRSDDQLENRFEPMMLPVWEANDD
                     CCSLLASFAASLPLRRPSPIATLDMARYLLTRSEGTIGELAHLLMAAAIVAVESGEEA
                     INHRTLSMAC"
     gene            complement(6593..>7026)
                     /locus_tag="IT892_004263"
     CDS             complement(6593..>7026)
                     /locus_tag="IT892_004263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000935451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137391.1"
                     /translation="DALKPWIARRERWPSFLIRRDPRDISRIWVLEPEGQHYLEIPYR
                     TLSHPAVTLWEQRQALAKLRQQGREQVDESALFRMIGQMREIVTSAQKATRKARRDAD
                     RRQHLKTSARPDKPVPPDTDIADPQADNLPPAKPFDQIEEW"
BASE COUNT         1451 a         2040 c         2026 g         1509 t
ORIGIN      
        1 gccctgtccg atcagatgca ccgtgtttca atcgacagct tccaaccgga aacccagcgc
       61 tatgcgctca agcgcggcgt gggctacctg aacgatatcc aaggatttcc tgaccctgcg
      121 ctctatcccg atattgctga ggcggactgc aggctggtgg ttatgcactc agcgcagcgg
      181 gatggcatcg ccacccgcac cggtcacctt cgacccgaag acgcgctcga cgagattgtg
      241 cggttcttcg aggcgcgggt ttccgccttg cgacggagcg gggtcgctgc cgaccggctc
      301 atcctcgatc cggggatggg atttttcttg agccccgcac cggaaacatc gctgcacgtg
      361 ctgtcgaacc ttcaaaagct gaagtcggcg ttggggcttc cgctattggt ctcggtgtcg
      421 cggaaatcct tcttgggcgc caccgttggc cttcctgtaa aggatctggg tccagcgagc
      481 cttgcggcgg aacttcacgc gatcggcaat ggcgctgact acgtccgcac ccacgcgcct
      541 ggagatctgc gaagcgcaat caccttctcg gaaaccctcg cgaaatttcg cagtcgcgac
      601 gccagagacc gagggttaga tcatgcctag cattcacctt ccggccgccc gctagcggac
      661 cctggtcagg ttccgcgaag gtgggcgcag acatgctggg ctcgtcagga tcaaactgca
      721 ctatgaggcg gcggttcata ccgcgccagg ggagcgaatg gacagcgagg agcctccgaa
      781 cgttcgggtc gcctgctcgg gtgatatcga cgaggttgtg cggctgatgc acgacgctgc
      841 ggcgtggatg tccgccaagg gaacgcccgc ctgggacgtc gcgcggatcg accggacatt
      901 cgcggagacc ttcgtcctga gatccgagct cctagtcgcg agttgcagcg acggcatcgt
      961 cggctgttgc accttgtcgg ccgaggatcc cgagttctgg cccgacgccc tcaaggggga
     1021 ggccgcatat ctgcacaagc tcgcggtgcg acggacacat gcgggccggg gtgtcagctc
     1081 cgcgctgatc gaggcttgcc gccatgccgc gcgaacgcag gggtgcgcca agctgcggct
     1141 cgactgccac ccgaacctgc gtggcctata cgagcggctc ggattcaccc acgtcgacac
     1201 tttcaatccc ggctgggatc caaccttcat cgcagaacgc ctagaactcg aaatctaacg
     1261 tccgttcggg catcgaggtc catgtcgggg tgggacgggc ccgtggcttc aagatcactt
     1321 gcagtccgac cgcgatgtct tggttgcgcg agaggttgtc gatatcctcc acttccatca
     1381 tcaaccctgg ataatgccgc cgccgtcatc gccgccgacg cccgtgccgg gcttttcggg
     1441 cctgtcaggc ttgctcggcc ttcagcctgc ctgggcgaga tctccggcgg acggattaac
     1501 ggcggagctt cgccgccttt cgtgcgtgtg aaggccgaag atagttctct caaaaacatc
     1561 cgtttatgag agataccaaa gccgacagtc tgccgaaggt tgaaggtctc tcaaaactgc
     1621 ctctcgcttc cgatctctca ccgatctact gttgatttgc acccaaattt gacccgggat
     1681 ttgcattgaa ttttgaccca ccccttgttg tcagaattat gtctcgattt tcagtttgcg
     1741 ggtctgtttt tcctcctgct tattctgagt tgaactgtgt ttgaagcggt aactttcatt
     1801 gccggtttcc aggatgtggc agtggtgggt tagtcggtcc aacaacgctg ttgtcatctt
     1861 ttcatcgcca aacactcggc tccattccga gaagctcaag ttggtggtca gtatcacgct
     1921 ggttttttcg tacagctttg agagcaggtg aaacagcagt gccccaccgg tttggctaaa
     1981 aggcaaatat cccagctcat ccagaatcac caaatcggca tacaacagac ggtttgcgat
     2041 ttgtccctga cgcccagatg atttctcttg ctccagtgca ttgaccaaat ccacggtgga
     2101 gaagaaacgc acccgtcggt tcaagtgcat cactgcttgt gtaccaatgg ctgtggccag
     2161 gtgagtcttg cctgtgcctg gcccaccaat cagcaccacg ttctgggctt gttccatgaa
     2221 gtcgcaccgg tgcaattgtt tgaccgtggc ctcattaact aggctttgac tgaagtcaaa
     2281 gcccaccaag tcccgataca cggggaactt ggccacccgc aattgatagt tcaccgaacg
     2341 tacttcacgc tctgccactt cagctttaat caagctgtcc agcatgggca aggcttgatt
     2401 aaatgctggt gaattctgat tgcccaactc ctcaatggcg tgtgccatgc caaagagttt
     2461 caaggatttg aggattctca catggccttc atgctgcatc atgggctctc cttaaactgt
     2521 catagcggtt cacgttggcc tgtggttcca atgtcagcct taaccccttg ggaattggaa
     2581 tcggtttggg tggaggttct tcggtcaaac gtcccaacag attaagcaca tgctccttcg
     2641 atggcttgcc acactccaat gccaattcca cagcactgag taccgcacct tcatcgtggt
     2701 gcaatacaag ggccagaatt tccaccatgt cacggtcacc gccggggcgt tgcagcaaga
     2761 tggattgaag cttcttgaac gcgggtggca attcagcaaa tggcgcacca ttgcgcaacg
     2821 ccccaggttt cttctgaagc acagacaagt aatggtgcca gtcgtattgt gtgtggccac
     2881 gccgagcgtg gccactgcca aacaatcttg gatgctcggc aatgtgttgg ccttcggcag
     2941 ccatcaccag cttgtctgca taaatccgaa ggctgatggc cctgttggcg taactggcag
     3001 gaacgctgta gcgattgccc tcgtggtgaa caaggcaggt tgaagtgact cgcttggttt
     3061 gctccacgaa tgcatcaaag gcattgggta gcgccatcaa ctcgccttgt tcatcggcaa
     3121 aggcctcttg cacggtttgg tccaattcgg ggtggcgcag ctcagaccac agcgctttgc
     3181 agcgatgctc aagccacaca ttcaaatcag caaggctttg aaagtctggt gccccttgcc
     3241 acaggcgttg gcgggaatcc tgcacgttct tctcaatctg gcctttctcc caacccgatg
     3301 ctggattaca gaactgcgca tcaaacaggt agtggctgac catggcagtg aaccgctgat
     3361 tgaccctgcg ctctttgcca cgccccaccg aatccacagc ggtcttcatg ttgtcgtaga
     3421 tgccgcgctt gggaatgcca ccgaagattt gaaaggcatg ccagtgggca tcaaacagca
     3481 tttcatgttt ttgctggtag taagcccgaa gcacaaaggc ccggctgtgg gccaacttaa
     3541 actgggcaat ctgaagtttg acctgtttgc ccgctatgcg ggcaaagtcc tcactccaat
     3601 cgaattggaa ggcttcgcca caagcaaagc gcaaggggat gaaacaaccc ttgcccgagg
     3661 tttgcgcctt gaactgttcg gaatctttcc actgtcgggc aaaggcacac actcggtcat
     3721 aagacccggt aaagcccaaa gcgaccaaat cccggtacat gctgcgcagg tttctgcgca
     3781 gcttctttgt ctttttgtgc tcggtggaga gccactgcct taacttgggc tcaaaaggac
     3841 ttaacttgcc aacgctgtct cgcgctgggt actgcggttc aaccaccttg ctttgcaaat
     3901 acttgcgaac ggtgttcctg gacaggccgc ttcgtcgggc tatttcccga atcgacgcac
     3961 catcgcgaaa atgccagcgt cgaattgcgc tcaatatcgc cacgtttatc actccttgat
     4021 ttctcccgcc atatccagac gggaaacagt gtcatacgtg ggtcaaattt cgacgcaaat
     4081 ctttacccta agttggggtg cggacaaaat cttggactac tttaggagta gttcatgtat
     4141 tcgtatgaag atcgccttcg agccgtgagg ttgtacctga agcttgggcg ccggatgagc
     4201 gccacactac ggcagctggg ataccccacc aagaactcgc tgaaggcctg gttggcagaa
     4261 ttcgaacgga atcaggatct tcgccgaggc tatcaacgga taaaacggca gtacaccgat
     4321 gagcaaaagc aacgggcagt agatcactat atcgaacaag gctactgcct gagtcacaca
     4381 atccgaagcc tgggctaccc aagccgcgag gccttgcgtg cctggatccg tgatttacgc
     4441 cctgaattcg ctaggacggt cgtcggcagc agcgctccca cagtcgcccg ctctcgcctc
     4501 gagaagcagc aagccgtcat tgcactgaac ctgcgcgtag gttcggcaaa ggatgtggcc
     4561 gacactgtcg gtgtatcgcg accaacgttg tataactggc agcatcgatt acttggcaaa
     4621 gtgcccctaa aacccatgac aaagaagaaa ggtgacacct cgctcgagca gcggcatgag
     4681 gcactactca gggaactggc cgaactggag agccagaacc agcggcttcg catggagaat
     4741 gcaattctgg agaaggcgag tgaattgata aaaaaagaca tgggcatcaa ccccctcgaa
     4801 ctgacaagcc gagaaaaaac gaaggtggtt gatgccctca gagtcacgtt tccattagcc
     4861 aatctgttgt gcggcctgaa gctggcgcgc agcacatact tctatcaacg cctgcggcag
     4921 acgcggcccg acaagtacac gcaggtgcgt gaggtcattc ggactatctt cgaggacaac
     4981 taccgctgct atggctatcg acgcattgat agtgccttgc gccttggtgg catgcgtgtg
     5041 tccgagaagg tcgtgcgtcg cttgatggcg caagagcgtc tggtcgtgag aacaccgcgc
     5101 cgccggcgct tctcggcgta tgctggcgac ccgacaccag cggtcccgaa tctgctgaat
     5161 cgcgactttc acgcgtcggc gccgaatacg aaatggttga ccgatctgac ggaaatacac
     5221 attccggcag ggaaggtcta cgtctcgccg atcgtcgatt gcttcgatgg gctggtggtg
     5281 gcctggaata tcggcaccag cccggatgcg aacctggtca ataccatgct ggatcacgcg
     5341 gtacggacac tgcgacccgg tgagcatccg gttatccatt cggacagggg ctcgcattat
     5401 cgctggcctg cgtggatccg ccgcactgaa aatgcccaat taacgcggtc gatgtccaaa
     5461 aagggctgct cgccagacaa tgctgcatgc gagggctttt tcggacgatt gaagaccgaa
     5521 ctaatctacc cgaggaattg gcagcacgtg acgctgaaag acctcatgac gcgaatcgat
     5581 gcctatatcc actggtacaa cgagcgccgc atcaaagtgt cgcttggcgg gcgtagtccc
     5641 atcgagtatc gtcatgcggt cggattgatg tccgtataaa ccgtccaaga aatcgtccgc
     5701 acccccagtg ggtcaatttt agatgcaact caacaggcca tgctgagtgt gcgatggttg
     5761 atcgcttcct cgccgctctc cacggcgacg atggccgccg ccatcagcaa gtgcgccagt
     5821 tcccctatgg tgccctcgct gcgtgtgagc aggtagcgag ccatgtccag cgtggcaatt
     5881 ggggaaggcc ggcgcagcgg gagcgaagcg gcgaagctgg ccagcagtga gcagcaatcg
     5941 tcgttggcct cccataccgg cagcatcatc ggctcgaagc gattttccaa ctggtcatcg
     6001 gagcggatgg ctaggtaggc gtcgcgcgtg cctaccccaa ccaacgggat gcgcagttcg
     6061 ttgccgagga agcgcagcag gttgaggaat tcccggcggt tgacgctgtt gccggccagc
     6121 acgttgtgca gctcgtcgat caccagcatg cgcacgccga ccttgcgcag cagtgccaga
     6181 gccagttgct ccatttccgg caaccgtggg cgtgggcgca gcggcgcgcc catcgcggcg
     6241 agcagcgcga cgtagaagcg gatcacggac ggctcggacg gcatctgcac gaccaacacc
     6301 gggatgtgct cctggtcggc gtcggagctg gccgggtggg tgcggcggaa cttctcgacg
     6361 atcatcgact tgccattgtt ggtcgggcca accagcagca ggttgggcat gcgttgcttg
     6421 tttggccacg cataaagggc ttccagccgg ttcagcgcct cgactgcgcg cggatagccg
     6481 atccagcggt cggcgcgaag gcgctggatg cgctcgtccg ccggaagacg ggccaagccc
     6541 tgggccgccg gcagcaggtg ggacaggtcg atgatgggat attcgtccac ggctaccact
     6601 cctcaatctg gtcgaacggt ttggcgggtg gcaagttgtc tgcctgcggg tcggcaatat
     6661 ccgtatccgg cggaacgggc ttgtccggcc gagctgatgt cttgaggtgc tggcggcgat
     6721 ccgcgtcacg ccgcgccttg cgtgtggcct tctgcgcgct ggtcacaatc tcacgcatct
     6781 ggccgatcat gcggaacagc gccgactcat ccacctgttc gcgcccttgc tgccgcagtt
     6841 tcgccagcgc ctgccgttgt tcccagaggg tgacagccgg atgcgacaag gtacggtagg
     6901 gaatttccag gtaatgctgt ccctccggtt ccaggaccca gatacggctg atgtcgcgcg
     6961 gatcgcgccg gatcagaaag gacggccagc gttcacgccg cgcaatccac ggcttgagcg
     7021 catcgg
//
LOCUS       DACAOP010000162         7016 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.162, whole genome shotgun sequence.
ACCESSION   DACAOP010000162 DACAOP010000000
VERSION     DACAOP010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7016
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.162"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(181..858)
                     /gene="narI"
                     /locus_tag="IT892_004264"
     CDS             complement(181..858)
                     /gene="narI"
                     /locus_tag="IT892_004264"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HAP3137392.1"
                     /translation="MQFLNMFFFDIYPYIAGAVFLIGSWLRYDYGQYTWRAASSQMLD
                     RKGMNLASNLFHIGILGIFVGHFFGMLTPHWMYEAWLPIEVKQKMAMFAGGASGVLCL
                     IGGVLLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
                     GWAQSVVTFHGGASQHLDGVAFIFRLHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKY
                     QLVRARH"
     gene            complement(858..1568)
                     /gene="narJ"
                     /locus_tag="IT892_004265"
     CDS             complement(858..1568)
                     /gene="narJ"
                     /locus_tag="IT892_004265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HAP3137393.1"
                     /translation="MIELVIVSRLLEYPDAALWQHQQEMFEAIAASKNLPKEDAHALG
                     IFLRDLTTMDPLDAQAQYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLLAQYEQHG
                     LQLNSRELPDHLPLYLEYLAQLPQSEAVEGLKDIAPILALLSARLQQRESRYAVLFDL
                     LLKLANTAIDSDKVAEKIADEARDDTPQALDAVWEEEQVKFFADKGCGDSAITAHQRR
                     FAGAVAPQYLNITTGGQH"
     gene            complement(1565..3103)
                     /gene="narH"
                     /locus_tag="IT892_004266"
     CDS             complement(1565..3103)
                     /gene="narH"
                     /locus_tag="IT892_004266"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HAP3137394.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNV
                     ETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYE
                     PFDFDYQNLHTAPEGSKSQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKN
                     FDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCR
                     GWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYD
                     ADAIERAASTENEKDLYQRQLDVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMA
                     MEWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLAN
                     LLTAGDTKPVLRALKRMLAMRHYKRAETVDGKVDTRALEEVGLTEAQAQEMYRYLAIA
                     NYEDRFVVPSSHRELAREAFPEKNGCGFTFGDGCHGSDTKFNLFNSRRIDAIDVTSKT
                     EPHP"
     gene            complement(3100..6843)
                     /locus_tag="IT892_004267"
     CDS             complement(3100..6843)
                     /locus_tag="IT892_004267"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HAP3137395.1"
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVR
                     SSWQEVNELIVASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFY
                     DWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRY
                     TDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIG
                     FRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELEN
                     VLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWA
                     EQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCG
                     CVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV
                     TAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVD
                     YTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQ
                     GKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDM
                     NTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHD
                     SAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIGNGG
                     KGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAW
                     AALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNV
                     HELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKEVIGQKSNGNQEKALN
                     FLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKDLGIADNDWIEVFNSNGALT
                     ARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAH
                     LAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK"
BASE COUNT         1542 a         1996 c         1832 g         1646 t
ORIGIN      
        1 cttccttaaa taatcaaaac ctgttactcc gagctaattt tgcccgatgg caccacgttt
       61 accgggccta caatatcctc ccctgtaggt cggataagcg aagcgcatcc gacaactcac
      121 cccgcaccgt gcccataaaa aaaccccgcc gaagcagggt ctatgtgaac taaaattcgc
      181 ttagtgacga gcgcgcacca gctggtactt acgtgtcaga tactccaccg gtacgctcca
      241 gatgtgtacc agacgcgaga acgggaacag caggaataac gtcatcccca gcaccaggtg
      301 cagacggaag ataaacgcca caccatcgag gtgttgagaa gcgccaccgt ggaaggtcac
      361 caccgactgc gcccagccaa ccagtttcat catctcgcta ccgtccatat gctgagcgga
      421 gaacggaatg gtcaacaggc ccagcgcgca ctggataacg agcagcgaca ggatcaggat
      481 atccgctccg gtagtggttg cacgcacgcg tgggctgaac agacgacgtt tcagcaacag
      541 cacgccgcca atcagacaca gcacgccgct ggcaccacca gcaaacattg ccattttctg
      601 tttcacttca atcggcagcc aggcttcata catccagtgc ggcgtcagca taccgaagaa
      661 gtgaccgaca aaaatcccca gaatcccgat atggaacagg ttcgacgcca ggttcatccc
      721 tttgcgatcc agcatctggc tggacgccgc gcgccaggtg tactgcccgt agtcataacg
      781 cagccagcta ccaatcagga agaccgcccc ggctatgtac gggtagatat caaagaagaa
      841 catattcagg aattgcatta gtgctgtcct ccggtggtga tattcagata ttgcggcgcg
      901 acggcaccgg caaagcgacg ctgatgcgca gtgattgctg aatcaccgca gcctttgtca
      961 gcaaagaatt taacctgctc ttcttcccag acagcatcca gcgcctgcgg cgtatcatcg
     1021 cgcgcttcgt cggcaatttt ttccgccact ttgtcgctgt cgatagcggt attcgccagt
     1081 ttcagcagca gatcaaacag cacggcataa cggctttcac gctgttgcag acgcgcgctc
     1141 agcaatgcca gaatcggcgc gatatctttc aaaccttcca cggcttcgct ttgcggcagc
     1201 tgcgccaggt actccagata cagcggcaga tggtccggca attcgcggct gtttaactgc
     1261 aagccgtgct gctcgtactg cgccagcagg tccaccatcg cctggccgcg gtcgcgggat
     1321 tcgccgtgca catgttcaaa cagcaacagt gacgtggcgc ggccacggtc gaacagttcg
     1381 ctgtactgcg cctgggcatc gagcggatcc atcgtcgtta aatcgcgcag gaaaatgccc
     1441 agcgcatggg catcctcttt tggcagattt ttcgacgcgg caatcgcctc aaacatctct
     1501 tgttgatgct gccataaggc agcatccgga tattcaagga gacgcgatac aatcacgagt
     1561 tcgatcatgg atgcggctcc gttttgctgg tcacatcgat ggcatcgata cgacggctgt
     1621 tgaacagatt gaatttggta tctgaaccgt ggcagccatc accaaaggta aagccgcagc
     1681 catttttctc cgggaaggct tcccgtgcca gttcacgatg actactcggc accacaaagc
     1741 gatcttcgta gttagcaatc gccagataac ggtacatctc ctgtgcctgg gcttcggtca
     1801 gaccgacctc ttccagcgca cgggtatcaa ctttaccgtc aacggtttca gcacgtttgt
     1861 aatgacgcat cgccagcata cgtttcagtg cgcgcagtac cggtttggta tcaccggcgg
     1921 tcagcagatt cgccagatac tgtaccggaa tacgcaggct ttcgacgtct ggcagaatgc
     1981 cgttgctacc cagctcaccc gcgtctgctg cagactgaat cggagacaga ggcggcacgt
     2041 accagaccat cggcagtgtg cgatattccg gatgcagcgg cagcgccagt ttccattcca
     2101 ttgccatttt ataaaccggc gactgctgtg cggcttcaat aacgctcagc ggaataccgt
     2161 ctttaatcgc ctgctcgatg actttcggat cgttcggatc gaggaacacg tccagctgac
     2221 gctggtaaag atctttctcg ttctcggtgc tggctgcacg ttcaatagcg tcggcatcgt
     2281 acaacagcac gccaagataa cggatacgac cgacacaggt ttctgagcac acggtcggct
     2341 gacccgcttc aatacgcgga tagcagaaga tgcacttctc agacttaccg ctcttccagt
     2401 tgaagtagat ttttttgtac gggcatccag tgatgcacat acgccagcca cggcatttat
     2461 cctggtcgat caggacgatg ccatcttctt cacgcttgta aatcgcaccg ctcgggcagg
     2521 tcgccacaca tgccgggttc aggcagtgtt cgcacaggcg cggcaaatac atcatgaagg
     2581 tgttttcgaa ctggctatac atcgccttct ggatgttgtc gaagttcttg tctttcgcca
     2641 gtttgtcaaa ctcaccgccc aggtcatctt cccagttcgg ccctttttcg attttcgcca
     2701 tccgttcccc ggtaatcagc gaacgcggac gggcaatcgg ctgcgatttg ctgccttccg
     2761 gcgcggtatg caggttctga tagtcaaaat cgaacggctc gtaataatcg tcgatccccg
     2821 gcagatgcgg gttagcgaag attttaccca gcagcatggc acggttaccc atgcgcggct
     2881 gcagtttgcc gttgatttta cggatccagc cgcctttgta tttttcctgg ttttcccagt
     2941 cagtcgggaa gccctggccc ggcttggttt ccacgttgtt gaaccacgca tattccacgc
     3001 cttcacggct ggtccagacg tttttacagg taactgaaca ggtgtggcag ccgatgcact
     3061 tatcgagatt cagcaccatg ccgacttgtg aacgaatttt cattttacgc tctcctgtac
     3121 ctggtcattg ccttcgccat ctaaccagtc aatgttcttc atcttacgca ctacaacaaa
     3181 ctcatcgcgg ttagaaccta cggtgccata gtagttaaag ccgtatgcca gatgggcata
     3241 gccgccgatc atatgcgtcg gtttcggcgt gatacgggtg accgagttat ggataccacc
     3301 acgctgttgg gtaatttccg aaccaggcag gttaacgata cgttcctgcg cgtggtacat
     3361 catggtcatc cctgccggaa cacgctggct gacaaccgca cgggcagtca gagcaccgtt
     3421 gctgttgaag acttcaatcc agtcgttatc ggcgataccc agatctttgg catcggcttc
     3481 actcaaccag accaccggac caccgcgacc taaagtcagc atcagcaggt tgtcgctgta
     3541 ggtggagtgg ataccccact tctggtgcgg cgtcaggaag ttgagcgctt tttcctggtt
     3601 gccgttggat ttctggccta tcacttcttt caccgaacgg gtgtcgatcg gcggacgata
     3661 aaccagcagg ctttcaccga aatcacgcat ccactggtga tcctgataca gttgctgacg
     3721 accagagagc gtacgccatg ggatcagctc gtgaacgttg gtgtaaccgg cgttgtaaga
     3781 aacgtgttca tcttccagac cagaccaggt cgggctggag ataattttgc gcggctgtgc
     3841 ctgaatatcg cggaagcgga tcttctcgtc ttctttattc agcgccagat gcgtatggtc
     3901 acgaccggta aattcgctca gggcagccca ggctttcacg gctacctgac cgttggtttc
     3961 cggtgccagt gtcaggatca tctctgccgc atcaattgcg gtgttcagca tcggctggcc
     4021 tttcgccgga ccttccgctt tggtgtagtt gagcttacgc agcagatcca tctcgctctg
     4081 ggtgttccag gcaatccctt taccgccatt accgattttc tccatcagcg ggccgataga
     4141 ggtaaagcgt tcgtaagtcg ccggataatc gcgctctacg accataatgt gtggcgcggt
     4201 tttacctggg atcaggtcgc actcgccttt tttccagtct ttcacatcca gcggctgcgc
     4261 cagttcagcg gcagagtcat gctggatagg cagcgtgacg atgtcggttt ctttacccag
     4321 atggccgacg cacacttcgg agaatttctt cgcgatggct ttgtagattt cccagtcgct
     4381 tttcgcttcc caggccggat cgaccgccgc agacagcggg tgaataaacg gatgcatatc
     4441 cgaagtattc atgtcgtctt tttcgtacca ggtcgccgtc ggcaaaatga tgtcggaata
     4501 gagacaggtg ctcgacagac ggaagtccag cgtaaccacc agatccagct tgccttccag
     4561 accattgtcc tgccagtcca cttcttccgg cttcacgccg ccctgttgcc ccagatcttt
     4621 accctggata ccgtgctccg tccccagcag gtacttgagc ataaactcat gacctttacc
     4681 ggaagaaccg agcaggttag aacgccagat gaacaggttg cgcgggtggt ttttaccgtt
     4741 ttctggttgt tctgccgcaa aacggatgga accctctttc agggatttca ccgtatagtc
     4801 caccggattc atcccggctt tttccgcttc gccagcgata gtcagcgggt tagtgcctaa
     4861 ctgcggtgca gacggcagcc agcccatgcg ttccgcacgg acgttaaagt cgatcaagtg
     4921 tccggtatag cgggatttgt ccgccatcgg tgacagcaac tcttccgccg tgacggtttc
     4981 ataacgccac tggctggagt ggttatagaa ataagaagtg ctgttcatgt gacgcgccgg
     5041 acgctgccag tcaagggcaa acgccagcgg ctgccagccg gtttgcggac gcagtttttc
     5101 ctgacctaca tagtgcgccc agccgccccc gctctgaccg acacagccgc agaaaatcag
     5161 catgttgatc agaccacgat agttcatatc gaggtgatac cagtggttca gccccgcacc
     5221 gacgataatc atcgaacgac cgtgcgtttt atcagcgtta tcggcaaatt cacgggcgat
     5281 gcgaataatc tggctgcgag aaacgccggt aatctgctcg gcccaggccg gggtataagc
     5341 tttcacatcg tcatagctgg ttgcacagtt aacgtcgttc aggccacgtt ccagaccgta
     5401 gtttgccagc gtcagatcat aaacggtggt caccagggcg gtgctgccat cagccagttg
     5461 caggcgtttc accggcagtt tgtgcagcag cacgttttcc agttccactt tgttgaagtg
     5521 ttccgtgccg tcgccaccaa agtacgggaa gcctacctca gcgatctcat cctggctacc
     5581 cagcaggctc agttgcagct cggtttcttc gccagttttg ccgtcgcgct gctcaagatt
     5641 ccatttgccc ttctcgcccc agcggaagcc aatagaaccg ttcggcgcaa ccatttcgcc
     5701 attggtatta aaggcgacag ttttccattc cggattgttt tcctggccca gcgcatcaac
     5761 cagatcagca gcgcgcagca tacgacctgc agcgtagtaa ccgtcgcgtt cttccagcat
     5821 caccagcatc ggcatgtcgg tgtagcgacg cacatagtcg gtgaaatact ggcttgggtt
     5881 gtcgaggtgg aattcacgca gcattacgtg gcccatcgcc agcgccattg ccgcatcggt
     5941 gccctgtttc ggtgccagcc acagatcgca cagtttggcg atttcagcgt agtctggtgt
     6001 gacggcaaca gttttggtcc ctttgtaacg cacttcagta aagaagtgag catccggggt
     6061 acgcgtctgc ggcacgtttg acccccaggc gatgatgtag ctggagttgt accagtcagc
     6121 agattccggt acgtcagttt gctcgcccca ggtttgcgga gacgcaggag gcaagtcgca
     6181 gtaccagtcg tagaagctta agcaagtacc gccaatcagc gagagatagc gtgcacccga
     6241 tgcgtaagaa accatcgaca ttgccggaat tggcgagaaa ccagcaacac ggtccgggcc
     6301 gtagtttttg atggtgtaaa cgttagatgc gacgatcagt tcgttcacct cctgccagga
     6361 agaacgaaca aatccaccgc gtccacgcgc ctgcttaaag cttttcgctt tatcggcgtc
     6421 ttcaatgata gaagcccatg cctcaaccgg atcgctatgc agcgccttcg cttcacgcca
     6481 cattttcatc aggcgtttgc gcatcatcgg gtatttcagg cggttggcac tgtaaagata
     6541 ccaggagtag ctggcaccgc gcgggcagcc gcgaggttca tggtttggca gatccggacg
     6601 ggtacgcgga tagtcagtct gctgggtttc ccaggtgacc agaccgtttt tgacgtagat
     6661 tttccagctg caggagccgg tgcagtttac cccgtgggta gagcggacga ttttgtcatg
     6721 ctgccaacgc tggcgatatc catcctccca gtcacggttg gtattgagaa gctggccatg
     6781 cccatcggca aaggtttcac ccttctgttt gaagtagcga aaccggtcca ggaatttact
     6841 catcggtttt ctcctgtggg agcctgtcgg ccctctgata aatcgacatt gctaatgttt
     6901 aagggcaagg taacgctctg aaacagcgtg ggaattgata acgatcaaga gtgatgggga
     6961 tgaaaaataa agtaaattcc taagataccc ctttaggata attaacagcc accaca
//
LOCUS       DACAOP010000163         6776 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.163, whole genome shotgun sequence.
ACCESSION   DACAOP010000163 DACAOP010000000
VERSION     DACAOP010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6776
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.163"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            141..1586
                     /gene="tldD"
                     /locus_tag="IT892_004268"
     CDS             141..1586
                     /gene="tldD"
                     /locus_tag="IT892_004268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HAP3137396.1"
                     /translation="MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSY
                     HESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRD
                     SGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
                     GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLD
                     GEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRR
                     GTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQ
                     DKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFG
                     GGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNG
                     VGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA"
     gene            complement(1720..2649)
                     /gene="aaeR"
                     /locus_tag="IT892_004269"
     CDS             complement(1720..2649)
                     /gene="aaeR"
                     /locus_tag="IT892_004269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AaeR"
                     /protein_id="HAP3137397.1"
                     /translation="MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDEL
                     QVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTM
                     AQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
                     MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRF
                     VTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDK
                     LPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK"
     gene            2832..3035
                     /locus_tag="IT892_004270"
     CDS             2832..3035
                     /locus_tag="IT892_004270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AaeX family protein"
                     /protein_id="HAP3137398.1"
                     /translation="MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFV
                     WHPALFNTALYCCLFYLISRLFV"
     gene            3043..3975
                     /gene="aaeA"
                     /locus_tag="IT892_004271"
     CDS             3043..3975
                     /gene="aaeA"
                     /locus_tag="IT892_004271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeA"
                     /protein_id="HAP3137399.1"
                     /translation="MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFS
                     ADVVAIAPDVSGLITQVNVHDNQLVKKGQILFTIDQPRYQKALEEAQADVAYYQVLAQ
                     EKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
                     ADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGS
                     NKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWP
                     AGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG"
     gene            3981..5948
                     /gene="aaeB"
                     /locus_tag="IT892_004272"
     CDS             3981..5948
                     /gene="aaeB"
                     /locus_tag="IT892_004272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeB"
                     /protein_id="HAP3137400.1"
                     /translation="MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAA
                     IVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIW
                     AGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCA
                     IMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQ
                     GMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDT
                     PVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATE
                     EEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTS
                     LAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIE
                     VQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSR
                     DRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTM
                     IIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEK
                     LRIWQAPPQVTEPVNRLAGMLHKYQHALTDS"
     gene            6040..6312
                     /locus_tag="IT892_004273"
     CDS             6040..6312
                     /locus_tag="IT892_004273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137401.1"
                     /translation="MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMN
                     DVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEELEGHLRFNVRH"
     gene            complement(6368..6631)
                     /gene="yhcN"
                     /locus_tag="IT892_004274"
     CDS             complement(6368..6631)
                     /gene="yhcN"
                     /locus_tag="IT892_004274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HAP3137402.1"
                     /translation="MKIKTTVAALSVLSVLSFGAFAADSIDAAQAQNREAIGTVSVSG
                     VASSPMDMREMLNKKAEEKGATAYQITEARSGDTWHATAELYK"
BASE COUNT         1588 a         1671 c         1827 g         1690 t
ORIGIN      
        1 cagccgttgc ctgatgcgac gctgtgcgtc ttatcaggcc tacaaaccgg aacataaccg
       61 taggctggat agggcgttca cgccgcatcc ggcagccgta aaaaatcctc tactgcagta
      121 actaacgagt agcaaaaacg atgagtctta acctggtaag tgaacaattg ctagcggcga
      181 acggcctgaa acatcaggac ttgttcgcga tcctcggtca actggccgaa cgtcgccttg
      241 attatggcga tctctatttt cagtcgagct atcacgaatc ctgggtttta gaagaccgca
      301 ttattaaaga tggttcttac aacatcgatc agggcgttgg tgtgcgtgca atcagcggtg
      361 aaaaaaccgg atttgcttac gctgaccaaa tcagcctgct ggcgctggaa cagagtgcgc
      421 aagcggcgcg caccatcgtc cgtgatagtg gtgatggtaa agtacagacg ctgggcgcgg
      481 tagagcatag cccgttgtat acctcggtag atccgctgca aagcatgagc cgtgaagaga
      541 agctggatat cctgcgtcgc gtcgataagg ttgcccgcga agcggacaag cgcgtacagg
      601 aagtgactgc cagcctcagt ggtgtctatg aattaatttt ggttgcggcc accgacggca
      661 cgctagcggc ggatgtccgt ccgctggtgc gtctttccgt gagcgttctc gtcgaagaag
      721 atggcaaacg cgaacgcggt gccagtggcg gcggcggtcg ttttggttat gaattcttcc
      781 ttgccgatct cgacggcgaa gtccgtgcgg atgcatgggc aaaagaagca gtgcgtatgg
      841 cgctggtcaa tctttctgcc gttgctgcac cagcgggcac catgccggta gtacttggcg
      901 caggttggcc gggcgtgctg ttgcatgaag cggttggtca cggtctggaa ggcgacttca
      961 accgccgtgg cacttcagta tttagtggac aggtcgggga gctggtggct tcagaactgt
     1021 gtaccgtggt tgatgatggc acgatggtcg atcgccgagg ttcggtggcg attgatgacg
     1081 aaggtacgcc aggccagtac aacgtgctga ttgagaacgg cattctgaaa ggctacatgc
     1141 aggataaact caacgcgcgt ttgatgggga tgacgccgac tggcaacggt cgccgtgaat
     1201 cctacgccca tctgcccatg ccgcgtatga ccaacaccta tatgctgccg ggtaaatcga
     1261 ccccgcagga aattattgaa tccgttgagt acggtatcta tgcaccgaac tttggtggcg
     1321 gtcaggtgga tatcacctcc ggcaaattcg ttttctccac ttcagaagca tatctgattg
     1381 aaaacggtaa agtaacgaag ccggtgaaag gcgcaacgtt gattggttcc ggtatcgaaa
     1441 ccatgcagca gatttcgatg gttggcaacg acctgaaact ggataacggc gtgggtgtct
     1501 gcggtaaaga agggcaaagt ttgccggttg gcgtgggcca gccaacgttg aaagtcgata
     1561 acctgactgt tggcggtact gcgtaataat ttcactattt tcagaaggat aattaatctt
     1621 tctacgtgca cgaacggtcc cctcgcccct ttggggtgag ggttagggtg aggggaaccc
     1681 gttggcacag gtttgtacaa cgtaacagta caatatgaat tacttctctt tcccgcgccc
     1741 gtgcatctcc tgaaacaatt taccgacctc aacaaaataa tccgtcagcg agttgatcac
     1801 gacctgtacc ttcagcggca gcttatcttt ttcggtatat aacgcataaa ccgggcgtgg
     1861 atctgactgg taacgcggca gcaggatctc cagctcccca cgattgatct cgttgatcac
     1921 ccacatcagc ggcacgtagg cgatcccggc acccgccgtc agccagcgca ccagcgtcat
     1981 cggatcatta gtcacaaatc ttccttgtgg gatcaggcga gtcgagatcc cttccggtgc
     2041 gatcagttca aattcattgt cgggccgcac gctgtattca agccatgaat gactactcaa
     2101 atcggcgggt ttttccggta tgccgtattg tgtgagatag cttttcgcgg cgcacaccac
     2161 cattggcatc gcgcccagac ggcgggaaaa caggctggaa tcctgcaacg cgccgacgcg
     2221 gatcaccaca tccagaccgt cggcaatcag gtcgggggct ggaattccgg taaccagatt
     2281 gacgctcaaa cctgggtatt ctttcagcat tttggctgtc agcccggcga gaacattttg
     2341 tgccatagtt gaagaacagc caatgcgtag cgtcccgatg ggggtgttat tgaaggcata
     2401 cagttgctca tgaacatcct gcacttcatg aagcatacga cggcagccct ggtagtaaat
     2461 tctaccggct tcggtcaggc caatgctgcg tgtgctacgg tttaacagct ttacctgcaa
     2521 ctcatcttcc agttttgata ccgtctgact gatggacgaa acgctcatct gtagctgtct
     2581 ggcggcggcg gtaaaagagc caaattcaac tactttggca aacaccgaca tgcgttttag
     2641 tcgttccatt attcactctg acttaaaagt gatttagatc acataatata gataacagca
     2701 taacagttac gctaatatat taaatatcaa tctacagcaa tgttgctctc gcccggcttt
     2761 ccatgccctt ctctgcggcg acagatgctg aaaataataa cgcctgctct ctctttacaa
     2821 ccaaggtcaa catgagtctg tttcccgtta tcgtggtgtt tgggctgtcc ttcccaccga
     2881 tattttttga attgctttta tcactggcga ttttctggct ggtgcgccgg gtacttgtgc
     2941 caacaggtat ctacgacttt gtctggcatc cggcgttgtt caacaccgcg ctctattgct
     3001 gcttgtttta tttgatatcg cgactgttcg tttgaggttg aagtgaaaac actaataaga
     3061 aaattctccc gtacggccat cacggtcgta ttagtcattc tggccttcat cgcaattttt
     3121 aatgcctggg tctattacac cgaatccccc tggacgcgtg acgcgcgctt tagcgctgac
     3181 gtcgttgcga tcgcgccgga cgtttctgga ctcattaccc aggtgaatgt tcatgataac
     3241 cagctggtga aaaaaggaca gatactgttc accatcgacc agccgcgcta tcaaaaggcg
     3301 cttgaggaag cgcaagccga tgttgcttat tatcaggtac tggcacagga gaaacgccag
     3361 gaggccggac gtcgtaaccg tctcggtgtg caggcgatgt ctcgcgaaga gatcgaccag
     3421 gccaacaacg tactacaaac ggttctgcat cagttagcga aagcgcaggc gacccgcgat
     3481 ctggcaaaac tggatcttga acgcacggtg atccgcgcgc cagcagatgg ctgggtgacc
     3541 aacctcaacg tctataccgg tgagtttatt actcgaggat caacggcggt tgcgctggtg
     3601 aaacagaact ccttctatgt actggcctat atggaagaaa ctaagctgga aggggtgcgt
     3661 ccggggtatc gtgcagagat cacgccgctt ggcagtaaca aagtgctgaa agggactgtt
     3721 gatagtgttg ccgcaggggt caccaacgcc agcagcacgc gtgacgacaa agggatggcg
     3781 actatagact ctaaccttga atgggtgcgt cttgcgcaac gtgttccggt tcgtattcgt
     3841 ctcgacaacc agcaagagaa catctggcct gcgggcacca ctgctacagt ggtggtcact
     3901 ggcaaacaag atcgcgacga aagccaggat tcgttcttcc gtaaaatggc ccatcgcctg
     3961 cgtgagtttg gttaatcacg atgggtattt tctccattgc taaccaacat attcgctttg
     4021 cggtaaaact ggcgaccgcc attgtactgg cgctgtttgt tggctttcac ttccagctgg
     4081 aaacgccacg ctgggcggta ctgacagcgg cgattgttgc cgccggtccg gcctttgctg
     4141 cgggaggtga accgtattct ggcgctattc gctatcgtgg ctttttgcgc atcatcggca
     4201 catttattgg ctgtattgcc ggactggtga tcatcattgc gatgatccgc gcaccattat
     4261 tgatgattct ggtgtgctgt atctgggccg gtttttgtac ctggatatcc tcgctggtac
     4321 gaatagaaaa ctcgtatgcg tgggggctgg ccggttatac cgcgctgatc attgtgatca
     4381 ccattcagcc ggaaccattg cttacgccgc agtttgccgt cgaacgttgt agcgagatcg
     4441 ttatcggtat tgtgtgtgcg attatggcgg atttgctctt ttctccgcga tcgatcaaac
     4501 aagaagtgga tcgagagctg gaaagtttgc tggtcgcgca atatcaatta atgcaactct
     4561 gtatcaagca tggcgatggt gaagttgtcg ataaagcctg gggcgacctg gtgcgacgca
     4621 ccacggcgct acaaggcatg cgcagcaacc tgaatatgga atcttcccgc tgggcgcggg
     4681 ccaatcgacg tttaaaagcg atcaatacgc tatcgctgac gctgattacc caatcctgcg
     4741 aaacttatct tattcagaat acgcgcccgg aattgatcac tgatactttc cgcgaatttt
     4801 ttgacacgcc ggtagaaacc gcgcaggacg tccacaagca gctcaaacgc ctgcggagag
     4861 ttatcgcctg gaccggggaa cgggaaacgc ctgtcaccat ttatagctgg gtcgcggcgg
     4921 caacgcgtta tcagcttctc aagcgcggcg ttatcagtaa cacaaaaatc aacgccaccg
     4981 aagaagagat cctgcaaggc gaaccggaag taaaagtaga gtcagccgaa cgtcatcatg
     5041 caatggttaa cttctggcga accacacttt cctgcattct gggcacgctt ttctggctgt
     5101 ggacgggctg gacttccggc agtggtgcaa tggtgatgat tgcggtagtg acgtcactgg
     5161 caatgcgttt gccgaatcca cgcatggtgg cgatcgactt tatctacggg acgctggccg
     5221 cgctgccgtt agggctgctc tactttttgg tgattatccc taatacccaa cagagcatgt
     5281 tgctgctgtg cattagcctg gcagtgctgg gattcttcct cggtatagaa gtacagaaac
     5341 ggcgactggg ctcgatgggg gcactggcca gcaccataaa tattatcgtg ctggataacc
     5401 cgatgacttt ccatttcagt cagtttctcg acagcgcatt agggcaaatc gtcggctgtg
     5461 tgctcgcgtt caccgttatt ttgctggtgc gggataaatc gcgcgacagg accggacgtg
     5521 tactgcttaa tcagtttgtt tctgccgctg tttccgcgat gactaccaat gtggcacgtc
     5581 gtaaagagaa ccacctcccg gcactttatc agcagctgtt tttgctgatg aataagttcc
     5641 caggggattt gccgaaattt cgcctggcgc tgacgatgat tatcgcgcac cagcgcctgc
     5701 gtgatgcacc gatcccggtt aacgaggatt tatcggcgtt tcaccgacaa atgcgccgca
     5761 cagcagacca tgtgatatct gcccgtagcg atgataaacg tcgtcggtac tttggccagt
     5821 tgctggaaga actggaaatc taccaggaaa agctacgcat ctggcaagcg ccaccgcagg
     5881 tgacggaacc ggtaaatcgg ctggcgggga tgctccataa gtatcaacat gcgttgaccg
     5941 atagttaagt caaaaccgac gccaaaagcg tcggtttttt catggctata cttagcgatg
     6001 cacggcagaa ctcgccgcga aacgtgacgg tggcaacaga tgaatattta tacctttgat
     6061 tttgatgaga ttgagagtca ggaggatttt tatcgtgact ttagccaaac ctttggtctg
     6121 gcgaaagata aggtacgcga tctcgactca ctatgggatg tgttaatgaa cgatgtcctg
     6181 ccgctaccac ttgagattga atttgttcat ctgggagaga aaacgcgtcg ccgttttggc
     6241 gcgttaatat tgctgtttga tgaggcagag gaagagctgg aagggcattt gcgttttaat
     6301 gttcgtcatt agcgcaaaaa aaagcccccg aaccgggggc aatatcgtcg gacaagacga
     6361 tgagggttta tttgtacagt tcagccgtag cgtgccaggt gtcaccgcta cgagcttcag
     6421 taatctggta ggccgttgcg cctttctctt ccgctttttt gttcagcatt tcacgcatat
     6481 ccattggcga agacgccaca ccacttacgg atacggtccc gattgcttca cgattttgtg
     6541 cttgtgcagc atcaatggag tcggcagcga atgcaccgaa agagagaaca gaaagtacgc
     6601 ttaatgcagc aacagtggtt ttgattttca tgatttttac ctcgacataa tcttttagct
     6661 gggcctttgt ttcgtgaccc atatcacaaa atcaagtata cactaattat tgagctaatt
     6721 aataccgcgc taactgtttc agttgatact aagtgttaaa aatgtgaatt ttaata
//
LOCUS       DACAOP010000164         6548 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.164, whole genome shotgun sequence.
ACCESSION   DACAOP010000164 DACAOP010000000
VERSION     DACAOP010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6548
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.164"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..1308
                     /gene="espX1"
                     /locus_tag="IT892_004275"
     CDS             <1..1308
                     /gene="espX1"
                     /locus_tag="IT892_004275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector EspX1"
                     /protein_id="HAP3137403.1"
                     /translation="KTEFLILFDDFFRSYNLPKPSPVLHHFFQYTHLRDAYFYRCKLI
                     EHTVQFYFFKHKGITLLRLDVFDDRTSECLSEEIKIYQECHEKFVKFLKANFNHEIYP
                     QLYTPEIFYEACRNLQSFYAHQETSQNAKYSAPDKKKSHLNQEIKKLIKKNIFPELYN
                     EQCNKIPSSSIDDNQGIMWQNFKTSNIAYSQLCKKLSLFKSIPSRLIEKSAYCSTENI
                     ITNKFDVVFSYCGDNVKEFILLLPYNKSLEMHELNEQNIQYLTALNINIHKMLLSNII
                     IEKSNLSYGYYFSCVLSNISCFESDLSNTIFSNGEINNLFIKKSNIFGTSFTNTRIKN
                     LRCEDIMPGRWTTQLVNKHLGYRYTGVFKTLASIDDKPSRFEILIPLVQTLVRDNVKL
                     NNDVYKELKKFMHDYDKTSPEMRKYLKSINECMFLMKNIAHQN"
     gene            1542..2894
                     /locus_tag="IT892_004276"
                     /pseudo
     CDS             1542..2894
                     /locus_tag="IT892_004276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308049.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
     gene            2907..3866
                     /locus_tag="IT892_004277"
     CDS             2907..3866
                     /locus_tag="IT892_004277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial family protein"
                     /protein_id="HAP3137404.1"
                     /translation="MKWLLLITLSLYSFIVQSAPCGLTNVGEQRGTYILKPLSMKGNL
                     TAEKIENTGNIIECADLQETTNAIKVHFLTQNAFRFKVGSRHYIINFPFESDGKKIEL
                     PGRSSYNLEEMLSAINFTIPYSIASVSDSSNTANIFPGTPFPLLFEIEVSSCTGNNTN
                     CNSVRFNYNLNTILQVNLMTCGFEDQSIDTGRFVLSRINNENYQFHHIRFDCIQGEQG
                     ELVFEPSDVEYYFEPVTIQESGTSILKNELENSEDGAGQVGFQLSNDGTNEIQYGKSN
                     YYSFQHPHEGSNQIPLFIRPRTYGNNVSSGQIMSRVKIVVVYN"
     gene            complement(3904..4803)
                     /gene="nhaR"
                     /locus_tag="IT892_004278"
     CDS             complement(3904..4803)
                     /gene="nhaR"
                     /locus_tag="IT892_004278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705976.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HAP3137405.1"
                     /translation="MSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEE
                     RLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADA
                     LSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGL
                     FSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEI
                     LGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAERM
                     IQHPAVQRICNTDYSALFSPAAR"
     gene            complement(4869..6035)
                     /gene="nhaA"
                     /locus_tag="IT892_004279"
     CDS             complement(4869..6035)
                     /gene="nhaA"
                     /locus_tag="IT892_004279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HAP3137406.1"
                     /translation="MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLET
                     PVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
BASE COUNT         2135 a         1386 c         1263 g         1764 t
ORIGIN      
        1 aaaacagagt tcttaatttt gtttgacgac ttttttagaa gctataactt gcctaaacca
       61 tctccagtcc ttcatcattt ttttcaatat actcatctga gagatgcata tttttataga
      121 tgtaaactca tagaacatac agttcaattt tattttttta aacacaaagg catcacatta
      181 cttagattgg atgtttttga tgacagaaca agcgaatgtc tttctgaaga gattaagata
      241 tatcaagaat gccatgaaaa attcgttaag tttttaaagg caaacttcaa ccatgaaata
      301 tacccacagc tatatactcc tgaaatattt tatgaggcct gcagaaatct ccagtcattt
      361 tatgctcatc aggagacatc acaaaacgct aaatatagtg caccagacaa gaaaaaaagt
      421 catcttaacc aggaaatcaa aaagctgatt aaaaaaaata ttttccctga gctatacaat
      481 gagcaatgca ataaaatccc ctcctcatcg atagatgata accagggaat aatgtggcag
      541 aactttaaaa ctagcaatat tgcatattca caactatgta aaaaattatc tttatttaaa
      601 agcataccca gtcgattaat agaaaaatca gcttattgct caactgaaaa cataatcacc
      661 aataaatttg atgttgtctt ttcttactgc ggagataatg taaaggaatt tatactttta
      721 ttaccctata ataaatctct ggagatgcat gaacttaacg agcaaaacat ccagtatttg
      781 actgccctta atattaacat acataaaatg ttgctatcaa atataataat agaaaagagc
      841 aacctttcat atgggtatta ttttagttgt gtattatcca atatatcatg ttttgaaagc
      901 gacttatcaa acaccatctt ttcaaatgga gaaataaaca acctcttcat taaaaaaagc
      961 aacatatttg gaacatcgtt cactaatacc aggataaaaa atttgcgctg tgaagatatt
     1021 atgcctggcc gatggaccac tcaacttgtc aataagcact taggttacag atacacagga
     1081 gtattcaaaa ccctggcaag tattgatgac aaaccgtccc gtttcgaaat tttgatacca
     1141 ttggtacaaa ctttagttcg cgacaatgta aagctaaata atgatgtgta taaagaactg
     1201 aaaaagttta tgcacgatta cgacaaaaca tccccagaaa tgagaaaata ccttaaaagc
     1261 atcaacgagt gtatgttcct tatgaaaaac atagctcatc aaaattaaaa aatctcaaaa
     1321 aagaagtaat ttcagaatga aattaactgt gatgattatt aattcactac agaggaataa
     1381 aaaataatct gaagcatgct ctgaaacatc ctactctatc attctaatga tagaaacttg
     1441 ctcttcttat aaagaaggga acaattaaga atattaaatt ttcaaacttt catcaacttc
     1501 acatcaagaa attaaaaaac ttaaacatta atctaaataa taacaacctg atcacataat
     1561 cgggtacgat tttatccgat aactataatg ctataactct gggaaatggt tggaatacac
     1621 cgctgggtgc catctctttt gacgctaccc gatcgagtag taagttaaat aatgatacca
     1681 gacacgaagg tacgagctat caggtcgcct ataataaata tctattgcaa acggccactc
     1741 actttagcgt ggccgcctgg cgttatgctt cgcaggatta taggacattc agcgaccatc
     1801 tttacgaaaa tgataaaata aatcatcaga gtgactatga cgatttttat aatattggca
     1861 gaaaaaatag cctttctgcc aatattatgc aacctttatc taataatctg ggaaatgtat
     1921 cattaagtgc gctttggcgg aattactggg ggcgaagtgg aaatgctaaa gattaccaat
     1981 tcagttattc caatagctgg caacgcatca gttatacttt ctctgccagc caatcctatg
     2041 atgaaaatga caaagaagag gagcgtttta atctgtttat ctccattcct ttctactggg
     2101 gggatgatat tgccaaaaca cgtcaccaaa ttaacttatc gaattcgacc tcattttcca
     2161 aagatggcta ttcctccaac aatactggaa ttactggcat agccggtgaa catgatcagt
     2221 taaattatgg tatatatgtt aatcagcaac aacaaaataa tgatacatcg cttggtacga
     2281 atttaagctg gagaactccc atcgccataa tagatggcag ctatagtcat tctaaaaacg
     2341 cctggcaaag tggtggaagt attagtagtg gattagttgt ctggtccggt ggtattaata
     2401 tcactaacca gttatccgat acatttgcaa ttctggatga gcctggatta gaaggcgcgc
     2461 atattaatgg acaaaaatac aaccgaacaa acagcaaagg ccaggttgtt tacgacccga
     2521 ttatacctca tcgtgaaaac catctggtac ttgatatagc aaacagtgaa agtgaaacag
     2581 aattgcaggg caatcgtcaa attattgcgc cttaccgtgg agcagtttct tatgtgcagt
     2641 ttacaactga ccaacgtaag ccctggtata tacaggcact gcgtcccgat ggttcgccat
     2701 taacctttgg ctatgacgta ctggatctcc aggaaaacaa tattggagtc gttggccagg
     2761 gtagtcgcct ttttattcgc gtagatgaaa ttccaactgg cataaaagtt gctctcaatg
     2821 atgaacagaa tttattctgt actattactt ttcaacacgt tatcgatgaa aacaaaacat
     2881 atatatgcca gtaaaaggag tttactatga agtggctttt attaatcacc ttgagtctat
     2941 attcttttat tgtgcaaagt gctccctgtg gattgaccaa tgtcggggaa caacgtggaa
     3001 catatatact caagccactg agtatgaaag gtaatctcac cgccgaaaaa attgaaaaca
     3061 ccggaaatat cattgagtgt gcagacttac aagagacgac caacgccatt aaagttcatt
     3121 ttttaacaca gaacgctttt aggtttaaag tcggaagtcg tcattatatt attaatttcc
     3181 cctttgaatc tgacggtaaa aaaatagagc ttccaggaag gtcatcttat aatttagaag
     3241 aaatgctatc tgcgataaat ttcaccattc catactctat cgcatctgta tcagatagtt
     3301 ccaacaccgc aaatattttt ccaggaactc cttttccttt gttgttcgaa attgaagtga
     3361 gttcatgtac agggaataat actaattgta atagcgtccg ctttaattat aatttaaata
     3421 ctattttaca ggtaaattta atgacctgtg gttttgaaga tcaatccatc gacactggac
     3481 gatttgtact gtctcgtatc aataatgaaa attatcagtt tcatcatata agatttgact
     3541 gcatccaggg cgagcaaggt gaattagttt ttgaacccag tgatgttgaa tattactttg
     3601 aaccagtgac gatacaggag tcaggaacca gcatattaaa aaatgagtta gaaaacagtg
     3661 aggacggtgc gggtcaagta ggctttcaac tctccaatga tggtacgaat gaaatccagt
     3721 atggtaaaag caattactac tcttttcagc atccccatga aggaagtaat cagattcctc
     3781 tatttattcg cccgcgtaca tatggaaata atgtctcaag cgggcaaata atgagccgag
     3841 tcaaaatcgt ggttgtgtac aactaatcta tctcctccac tttaactttg ggggagctgc
     3901 cgattaacgc gccgctggac taaaaagcgc agaataatcc gtattgcaga ttcgctgtac
     3961 cgccgggtgc tgaatcatcc gctcagcaaa aatagcatgg tactcttcca tcacattctc
     4021 gacgcgacca atttctacga cagttttatc ggcataaaag tcatatgcat aaagcgttgg
     4081 ggcaacgaag attgcattgt gcattgcacc aaaagctttc atcaacgcgg catcatcaaa
     4141 ctcgccgagg atttctacgt ttaatccctg ggagttaaac cagttaagca atttgcgccc
     4201 taacattgaa cgtcgcccag gaatcaaaag tcgccgttct tccagacaag ccgggaacgg
     4261 tttttctggt ggtggatttg tacaccagaa actcacgcca cattcgccaa ttctcacgga
     4321 gaacaggcct tcctgctgcg tagagtctat cggacagtcg gaaatgatca tatccagttt
     4381 atgctggctt aattgctcca gtagcatttc gtgggtggat tcgaagcagc gaagatgaat
     4441 cggctcgcct tctaccactg cagcattcag cacgctactg accaggcgtt tggaaagtgc
     4501 atcagccacg ccaacgtcaa acaataaatt ggattctttg cgatagttca caatatccag
     4561 catttcctgg cttaaggtga acattttatc ggcatagcga tagaccagtt ctcccagctc
     4621 gctgggttcg agaccacgtc ccttgcgctt aaataatttg ccttgcaggc gctcttccag
     4681 agcccggatc tgtccggtaa tggtttgtgg agttaaataa agcgcctccg ctgcgccaac
     4741 cacggaacct tctttataga catgccagaa gtaatacaag tggttgtaat tgatatgaga
     4801 catgctcatt tctctccctg ataacaatga aaagggagcc gtttatggct ccccggtaaa
     4861 ccgtcctgtc aaactgatgg acgcaaacga acgcgtaacc agctgtatcc aattaccgcc
     4921 gaagagatag aaccgaccag gataccgagt ttcgcccagt taatcagttc tggatctacg
     4981 ctaccaaagg ccaggctggc aataaagata gacatagtaa aaccgatacc gcacaggatc
     5041 cccaccgcca taatttgctg ataagtcgtt ccctcaggca gatgcgccag tttcaaacgc
     5101 agcgccaacc agcagaacag actaatcccc agcggtttgc caatcagcaa gccagcgatg
     5161 atccccaatg gcagaatgga ggtcaagcca tccagcgtga caccttgcag tgaaacgcca
     5221 gcattagcaa atgcaaacag cggcaaaatc agatacgcca cccacgggtg taacacatgc
     5281 tccagtcgct tcgctggaga acgcccatgc ttctctttca aaggaataaa gaagccgaca
     5341 attacccccg ccagggttgc gtgaaccccc gatttcaaca ccgcagtcca caacactacg
     5401 ccaaccagaa tatagacgcc cgtgcggcgt acaccacaca gattcaatac cgcgagtacc
     5461 gcaattgcta cagccgcgac gccaagagag gccatcgata agtcattagt gtagaacaat
     5521 gcgatgataa tgatggcccc aagatcgtcg ataatagcca gagccatcaa aaagatcttc
     5581 agcgctaacg gaacacgact tcccaacagc gccagcacac caagtgcaaa ggcaatgtca
     5641 gtagccgccg ggatcgccca cccttcgcgg gtaatcggat cggcatagtt aaaggccaga
     5701 tagagtaatg ccggaacaat catcccacca atagcggcga taactggaaa tgcggcctgg
     5761 cgtaagctgg ctagcgatcc ttgcatcagt tcacgtttaa cttccagacc gactaacagg
     5821 aaaaataccg ccatcagcgc gtcatttatc cataacagca tgtttttgtt gatttcgagt
     5881 gaaccaaccc ggagctgaac cggcgtctcc agaaagtcgt gataccatcc actggttgcg
     5941 ccgctattgg ccataatcat cgccaggata gcggcaatga taagaataat gcctcccgag
     6001 gcatcactgc taaagaatcg atgcagatgt ttcacttttt atttctcttt caggtgaata
     6061 gatcgttttt actattttac cccgcacaaa tcatcgttaa aatcagatta tagtgtagga
     6121 ataactcgtt ttttacgatc cattgaagaa tttgcgccat cagcggtgag atgagttttt
     6181 gacggctgta agcgctcacg agtgacccta agcccagata atcatagctt aaggtgagga
     6241 tttctgaggg attaattagg aaaagtaata attaatttct tgtcagtcgg cgttatttgt
     6301 taggacaata tttcaaaaat aatccagctt gtcgtcaata attgcgataa agagataaat
     6361 taaagttaaa taattaaatc attaaaaaat tacgccacaa aaatgcgagg cgtcttcagg
     6421 attagaatcg ataaaacaaa atgggttaaa gagagcgata taatagcggc gggtgcttga
     6481 ggctgtctgt ctcaggcatt agctgaacgg cagatagaga aaagccccga gtgatatttt
     6541 accatcaa
//
LOCUS       DACAOP010000165         6460 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.165, whole genome shotgun sequence.
ACCESSION   DACAOP010000165 DACAOP010000000
VERSION     DACAOP010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6460
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.165"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(1..624)
                     /locus_tag="IT892_004280"
                     /pseudo
     CDS             complement(1..624)
                     /locus_tag="IT892_004280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308691.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deaminated glutathione amidase"
     gene            717..1100
                     /gene="crcB"
                     /locus_tag="IT892_004281"
     CDS             717..1100
                     /gene="crcB"
                     /locus_tag="IT892_004281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HAP3137407.1"
                     /translation="MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLTANLIG
                     AFIIGIGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLN
                     VFVNLLGSFAMTALAFWLFSASTAH"
     gene            complement(1154..1363)
                     /gene="cspE"
                     /locus_tag="IT892_004282"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(1154..1363)
                     /gene="cspE"
                     /locus_tag="IT892_004282"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002436076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HAP3137408.1"
                     /translation="MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTL
                     AEGQRVEFEITNGAKGPSAANVIAL"
     gene            complement(1538..2098)
                     /locus_tag="IT892_004283"
     CDS             complement(1538..2098)
                     /locus_tag="IT892_004283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid:lipid A palmitoyltransferase"
                     /protein_id="HAP3137409.1"
                     /translation="MNVSKYVAIFSFVFIQLISVGKVFANADEWMTTFRENIAQTWQQ
                     PEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGLSRWDEKGNWHGLYAMAFKDS
                     WNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGP
                     VTFQMTYIPGTYNNGNVYFAWMRFQF"
     gene            2687..4072
                     /gene="dcuC"
                     /locus_tag="IT892_004284"
     CDS             2687..4072
                     /gene="dcuC"
                     /locus_tag="IT892_004284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HAP3137410.1"
                     /translation="MLTFIELLIGVVVIVGVARYIIKGYSATGVLFVGGLLLLIISAI
                     MGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMV
                     VKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
                     AAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFW
                     QRYLDKKEHISHEMLDVSEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVI
                     CMLIASILEFLRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAAGVFAQGLSTIGFIQ
                     SLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAY
                     LTIPMLQASNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELM
                     VPGTAAAVTGK"
     gene            complement(4113..4793)
                     /gene="dpiA"
                     /locus_tag="IT892_004285"
                     /gene_synonym="citB"
     CDS             complement(4113..4793)
                     /gene="dpiA"
                     /locus_tag="IT892_004285"
                     /gene_synonym="citB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator DpiA"
                     /protein_id="HAP3137411.1"
                     /translation="MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARM
                     MIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVF
                     DYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGID
                     PLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGR
                     PQRIYHSG"
     gene            complement(4762..6420)
                     /gene="dpiB"
                     /locus_tag="IT892_004286"
     CDS             complement(4762..6420)
                     /gene="dpiB"
                     /locus_tag="IT892_004286"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase DpiB"
                     /protein_id="HAP3137412.1"
                     /translation="MLQLNENKQFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTAS
                     FEDYLTLHVRDMAMNQAKIIASNDSVISAVKTRDYKRLATIANKLQRDTDFDYVVIGD
                     RHSIRLYHPNPEKIGYPMQFTKQGALEKGESYFITGKGSMGMAMRAKTPIFDDDGKVI
                     GVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIA
                     RVVRQQEALFSSVYEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIVEVVRPA
                     DFFTEQIDEKRQDVVANFNGLSVIANREAIRSGDDLLGAIISFRSKDEISTLNAQLTQ
                     IKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGESQAQQQLIDSLREAFAD
                     RQVAGLLFGKVQRARELGLKMIIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLR
                     SDEGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEHGIGLY
                     LIASYVTRCGGVITLEDNDPCGTLFSIYIPKVKPNDSSINPIDR"
BASE COUNT         1612 a         1623 c         1459 g         1766 t
ORIGIN      
        1 tatttttgtt cccgcactcc cccgccgcca ccatataaca ggtggtatcc agcgcacgag
       61 cggcaagcaa cgttgaccag tgatgctctt tgagcggccc gcgaacccag gcggcaggaa
      121 gtaccaggat ttcagctccc tgtaatgcct gtgccagcgc cagctctgga aagcgtaagt
      181 cataacaggt catcagaccg accttcatcc cttccacctc cagtaacgga gcgatttcat
      241 taccagcatc aacacggcgt gattcctgaa tggcaaatgc atcatagaga tgcagtttgg
      301 cataacgggc gacgatgttt cctgcctgaa gtgccaccag catattccat gcgcgccccg
      361 gcgttgaagg aacatgaatc gtcagaattg tcgtcatcat gttacgttta ctttctcgcc
      421 gtaaagtccg aggaattcgc cttccagcag ctgtgctgat ttaaccgata gatctgcatc
      481 atgatcatcg cgcgccagca atgcttccgg caggacaaac agcgatacgt cgttttccgc
      541 cgcctgcgcc atcaacgagg cacaaatctc agcgttcttt tcccacacag atgtaacagc
      601 aaactgtcct gcggcaacca gcattgccac ctcctgtcag agtcgtaaaa ttcgccaacg
      661 acgattattc ggcgttacac ttatcactca tacaaatcaa atagcaggat tttgcagtgt
      721 tacaacttct tttagcagtt tttattggcg gtggtacggg aagcgtggcg agatggctgt
      781 taagtatgcg atttaaccca ctgcatcagg cgattccgtt ggggacgctg acagcaaacc
      841 tgattggggc attcatcata ggaataggat tcgcatggtt cagcaggatg acgaacattg
      901 atccagtgtg gaaagtatta atcaccaccg gattttgtgg cggtctaaca accttctcaa
      961 cattttcggc agaagtggtg tttttgttac aagagggccg ctttggctgg gcattactga
     1021 acgttttcgt caaccttctg gggtcttttg ccatgaccgc actggcattc tggctgtttt
     1081 cggcctcaac cgcacactaa agaccaaaaa aaacccgctg attaagcggg ttttgaattc
     1141 ttgctgacgt atcttacaga gcgattacgt ttgcagcaga agggcctttg gcaccgttag
     1201 tgatttcgaa ctctacgcgc tgaccttcag caagagtttt aaaaccatta gtctggattg
     1261 cagagaagtg tacgaacacg tctttgctgc cgtcttccgg agtaatgaaa ccgaatcctt
     1321 tggactcatt aaaccactta acgttacctt taatcttaga catcaaaatt acctttacat
     1381 gaaaaataga cacaaatgct gtgtcggtta ccagtacacc aattgtggta cgctttgtcc
     1441 agtgtaactt tactaaaaag tgataaaagt cgcgttattt ttgatgttac ttattttagc
     1501 tattgatttt aaagaagtta ctaaaacttc atttgtctca aaactgaaag cgcatccagg
     1561 caaagtacac attgccattg ttgtaggtac ccggaatgta ggtcatctga aaagtcactg
     1621 ggccataacc cacggaggcc aatggcagta gaaccgggag agggatgtaa ttccagttat
     1681 cgcgtgccgt tacgccagcg gtgaatccca gacctaaatg aaaattttca tccgccagcg
     1741 gtcgccaggt actttcccat ccgtatccgg caatcggttc ccatttgttc cacgagtcct
     1801 taaatgccat ggcatacagg ccatgccagt ttcctttttc atcccaacgc gacaggccaa
     1861 aaccgccacc ccacggtcgc tcgttatagc gatcggtttt ttctttgtcg taagcgaaac
     1921 gtgcatgcca ggtgatggca ggaatatata aatcataatg ttcaggctgt tgccaggttt
     1981 gtgcaatatt ttctctaaac gttgtcatcc actcatctgc gttagcaaaa actttaccaa
     2041 cgctgattaa ctgaataaaa acaaaggaaa agatagcgac atatttactc acgttcattt
     2101 gtgaccataa aacatttatc aaaaatctac tactagcata gcaaagctac aattaacata
     2161 accttaatag acccaacata aagaataatc tgaatagctg ctctatttat ttccgcttgt
     2221 tcaagttaaa tatttccgcg catcgattaa agatgatgcg tcgttttctg cgatgggaat
     2281 agtcaaaaaa gaaaaaccaa gtcttttttg atgacaaaat gcaatcaagg aaaaattatt
     2341 ttatttttta acgagataca acaatcatct taacgaagta tataatatat atcgtcaacc
     2401 tatgctcata ttagattatt ttttgagcgc acagccgcag ctaacaccat tgcaattaac
     2461 aaatttgcat caatccacca tcaatttgca cacattatta tgtgataatt gccaaccgct
     2521 aaatatgcgt tttgttatct atgtataaaa acagcaactt caatgtctta atggcagttt
     2581 ttcttgattt taatcagcat tcatcgccaa tttattgggc atattttttc cttaagcttt
     2641 aggaattttt tattatttac tttggggcct ggagacagga aaaattatgc tgacattcat
     2701 tgagctcctt attggggttg tggttattgt gggtgtagct cgctacatca ttaaagggta
     2761 ttccgccact ggtgtgttat ttgtcggtgg cctgttattg ctgattatca gtgccattat
     2821 ggggcacaaa gtgttaccgt ccagccaggc ttcaacaggc tacagcgcca cggatatcgt
     2881 tgaatacgtt aaaatattac taatgagccg cggcggcgac ctcggcatga tgattatgat
     2941 gctgtgtgga tttgccgctt acatgaccca tatcggcgcg aatgatatgg tggtcaagct
     3001 ggcgtcaaaa ccattgcagt atattaactc cccttacctg ctgatgattg ccgcctattt
     3061 tgtcgcctgt ctgatgtctc tggccgtctc ttccgcaacc ggtctgggtg ttttgctgat
     3121 ggcaacccta tttccggtga tggtaaacgt tggtatcagt cgtggcgcag ctgctgccat
     3181 ttgtgcctcc ccggcggcga ttattctcgc accgacttca ggggatgtgg tgctggcggc
     3241 gcaagcttcc gaaatgtcgc tgattgactt cgccttcaaa acgacgctgc ctatctcaat
     3301 tgctgcaatt atcggcatgg cgatcgccca cttcttctgg caacgttatc tggataaaaa
     3361 agagcacatc tctcatgaaa tgttagatgt cagtgaaatc accaccactg ctcctgcgtt
     3421 ttatgccatt ttgccgttca cgccgatcat cggtgtactg atttttgacg gtaaatgggg
     3481 tccgcaatta cacatcatca ctattctggt gatttgtatg ctgattgcct ccattctgga
     3541 gttcctccgc agctttaata cccagaaagt tttctctggt ctggaagtgg cttatcgcgg
     3601 gatggcagat gcgtttgcta acgtggtgat gctgctggtt gccgctgggg tattcgctca
     3661 ggggcttagc accatcggct ttattcaaag tctgatttct atcgctacct cgtttggttc
     3721 ggcgagtatc atcctgatgc tggtattggt gattctgaca atgctggcgg cagtcacgac
     3781 cggttcaggc aatgcgccgt tttatgcgtt tgttgagatg atcccgaaac tggcgcactc
     3841 ttccggcatt aacccggcgt atttgactat cccgatgctg caggcgtcaa accttggccg
     3901 taccctttcg cccgtttctg gcgtagtcgt tgcggttgcc gggatggcga agatctcgcc
     3961 gtttgaagtc gtaaaacgca cctcggtacc ggtgcttgtt ggtttggtga ttgttatcgt
     4021 tgctacagag ctgatggtgc caggaacggc agcagcggtc acaggcaagt aaatagtaat
     4081 gccggaggca agtttcctcc ggctttatca tgtcacccac tgtggtatat gcgttgtggt
     4141 ctgccaactt tgccgtgaac aatttcagca ataatcagat ggcggctggc gcaatattca
     4201 agataacgcc tggcagtggt gcggctgatg gtcagtgcct gcgccaccgt ttctgccgta
     4261 tgttgcacac caggctcttt aaacagtttt cgcaccgcgt ttagcgtcaa ggggtcaata
     4321 ccggtcggta gctcgtcctt aggttcaccg cgagcataag cattaaacat ctcatcaatt
     4381 tgcttctggc tggcgctatc aatactttcc agcatatgtt tacgctggcg gaaacgggtt
     4441 agcgtttgcc ccagccgttc ataggcaatg ggcttaatga gataatcaaa tacaccacaa
     4501 cgtacggctt cagacaccgt ttccatatcg ctggctgcag tggtaaacac cacgtcgccg
     4561 ggataatgcg cctgcaccag ttcatgcagt aaattaatcc ctctaccgtc aggaagatag
     4621 ttatcgagca agattagccc cggcttaaaa cgctcgatca tcattcgggc ctgcgccaga
     4681 tttcccgcca gtaatatctg actgaatccg ggaatgtgac gaatatattc cgcatgcatc
     4741 tctgccagcg gcgtttcgtc ctcaacgatc aatagggtta atggagctgt cattaggttt
     4801 cactttcgga atatagattg aaaataaggt accgcaggga tcattatctt cgagagtgat
     4861 aacaccaccg cagcgcgtta cgtagctggc aatcaagtac aacccaatgc catgttcacc
     4921 gggctcgtca gcacgcgtac tgaccccctg ctcaaatatt ttgtctcgta gagactctgg
     4981 aacgccgcag ccctgatcgg cgacttcaat caccacatca tcgccttcat cgctgaggaa
     5041 taattcaacg atcttgtttc cttcatcgct acgcaggctg gcttcgaagg cgttatcaag
     5101 taaattgccc acaatggctg caaactcggt gctatccagt cctggcggca gttgcgaaag
     5161 ctggctaccg gggacaatga tcatttttag ccccagttcc cgggcgcgct gcactttacc
     5221 aaaaagcagc cccgccacct ggcgatcggc aaacgcctcg cgcaggctgt caataagctg
     5281 ttgctgggcc tgagactccc cctgcaccat cgccagcacg cgatcatact ctttcatctg
     5341 caacagacca ttgagcgtcg acatccaatt gagatgctcg tgtcgcaatg tacgaaggct
     5401 ctcaacgtat tgttttattt gcgtcagttg cgcattgagg gtggaaattt cgtctttact
     5461 acgaaagctg ataatggccc ccagcaaatc atcacctgaa cgaatagctt cccggttggc
     5521 aataacgctc agaccgttaa agttcgccac cacatcctga cgtttttcat caatctgttc
     5581 ggtaaagaaa tcggcgggcc tgaccacttc aacaatgggt ttacccaacc attgccgtcc
     5641 gggggaactc agccccagca tctttcttgc gttacgattg atggcggtaa tgtaaccatg
     5701 cggatccacc gcaatcagcc cttcataaac cgaactaaac agcgcctctt gctgacggac
     5761 cacgcgtgcg atttgctttg gctccatgcc catcatctgc cgacggatat gcgcggccag
     5821 gaaccacgac agcaacatca gaatccctaa cagcacgaca aacacacctg ccatcggtaa
     5881 taaaaactca gcccgccagc tatcgatttt actcaccagg tagccaatcg acaccacgcc
     5941 gatgactttt ccatcgtcat caaagattgg cgttttggcg cgcatcgcca tccccattga
     6001 ccctttcccg gtaatgaagt agctctcccc tttctccagc gcgccctgtt tggtgaactg
     6061 cataggataa ccaattttct ccggattagg atggtaaagg cggatcgagt gccggtcccc
     6121 aatcaccaca taatcaaaat cggtatctct ttgtaatttg ttagcgatgg tcgccagccg
     6181 tttgtagtca cgcgttttca ccgcagagat gacactgtca ttggaggcaa taattttcgc
     6241 ctgattcatt gccatgtcgc gtacatgaag cgttaaatag tcctcaaaac tggccgtaaa
     6301 atattgcgcc agggctgcaa tgacaaatat tgagaacacc agaatcagca aaaagatacg
     6361 cagcggaaat gccagtcttt ggaaaaatgc aaactgttta ttctcgttaa gctgcaacat
     6421 tgttttcctt gcgggttgtc ccgagcctct ttgacggatg
//
LOCUS       DACAOP010000166         6438 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.166, whole genome shotgun sequence.
ACCESSION   DACAOP010000166 DACAOP010000000
VERSION     DACAOP010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6438
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.166"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(388..654)
                     /gene="minE"
                     /locus_tag="IT892_004287"
     CDS             complement(388..654)
                     /gene="minE"
                     /locus_tag="IT892_004287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HAP3137413.1"
                     /translation="MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRK
                     DILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK"
     gene            complement(658..1470)
                     /gene="minD"
                     /locus_tag="IT892_004288"
     CDS             complement(658..1470)
                     /gene="minD"
                     /locus_tag="IT892_004288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HAP3137414.1"
                     /translation="MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLR
                     NLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGV
                     AKVLDDLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
                     ASKSRRAENGEEPIKEHLLLTRYNPGRVSRGDMLSMEDVLEILRIKLVGVIPEDQSVL
                     RASNQGEPVILDINADAGKAYADTVERLLGEERPFRFIEEEKKGFLKRLFGG"
     gene            complement(1494..2189)
                     /gene="minC"
                     /locus_tag="IT892_004289"
     CDS             complement(1494..2189)
                     /gene="minC"
                     /locus_tag="IT892_004289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HAP3137415.1"
                     /translation="MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLK
                     HAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGK
                     EKAPRPAPTPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIAD
                     GNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARL
                     QLVENALTVQPLN"
     gene            2709..3077
                     /locus_tag="IT892_004290"
     CDS             2709..3077
                     /locus_tag="IT892_004290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137416.1"
                     /translation="MNMMRIFYIGLSGVGMMFSSMASGNDAGGLQSPACGVVCDPYIC
                     VNSDGISPELTRKYLGEKAAENLQSLQGYDPREFTFANGVFCDVKEKLCRDDRYFGVD
                     GKRSGKINQTTTKMLFMCRE"
     gene            complement(3180..3581)
                     /locus_tag="IT892_004291"
     CDS             complement(3180..3581)
                     /locus_tag="IT892_004291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inhibitor of g-type lysozyme"
                     /protein_id="HAP3137417.1"
                     /translation="MKIKSIRKAVLLLALLTSTSFAAGKNVNVEFRKGHSSAQYSGEI
                     KGYDYDTYTFYAKKGQKVHVSISNEGADTYLFGPGIDDSVDLSRYSPELDSHGQYSLP
                     ASGKYELRVLQTRNDARKNKTKKYNVDIQIK"
     gene            3822..4115
                     /locus_tag="IT892_004292"
     CDS             3822..4115
                     /locus_tag="IT892_004292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137418.1"
                     /translation="MFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMIL
                     PLDGRKKLVNADIEKVKQALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK"
     gene            4187..4846
                     /locus_tag="IT892_004293"
     CDS             4187..4846
                     /locus_tag="IT892_004293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HAP3137419.1"
                     /translation="MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSAVPEEPVLF
                     IKPETALCDLRQPLAIPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDL
                     TLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPAAEFTGDPQNTTLSLSVNGEQRQQG
                     TTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGVGPLQSGDELTVTFDGHSLTTRV
                     L"
     gene            4923..5384
                     /locus_tag="IT892_004294"
     CDS             4923..5384
                     /locus_tag="IT892_004294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415699.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgN family cysteine cluster protein"
                     /protein_id="HAP3137420.1"
                     /translation="MAEHLMSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDED
                     TDEIYFTNVACRQLNIKTCQCRNYERRFEFEPDCIKLTRENLPTFEWLPMTCAYRLLA
                     EGKDLPAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ"
     gene            complement(5591..>6438)
                     /gene="hlyE"
                     /locus_tag="IT892_004295"
     CDS             complement(5591..>6438)
                     /gene="hlyE"
                     /locus_tag="IT892_004295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hemolysin HlyE"
                     /protein_id="HAP3137421.1"
                     /translation="ALDLYNKYLDQVIPWQTFDETIKELSRFKQEYSQAASVLVGDIK
                     TLLMDSQDKYFEATQTVYEWCGVATQLLAAYILLFDEYNEKKASAQKDILIKVLDDGI
                     TKLNEAQKSLLVSSQSFNNASGKLLALDSQLTNDFSEKSSYFQSQVDKIRKEAYAGAA
                     AGVVAGPFGLIISYSIAAGVVEGKLIPELKNKLKSVQNFFTTLSNTVKQANKDIDAAK
                     LKLTTEIAAIGEIKTETETTRFYVDYDDLMLSLLKEAAKKMINTCNEYQKRHGKKTLF
                     EVPEV"
BASE COUNT         1656 a         1433 c         1513 g         1836 t
ORIGIN      
        1 gaactggtcg ttctgaccat caacgattaa actgcgcttc ggcgcagttt tcgtttacag
       61 gatgttgaaa gggaaaattc tggggcaaaa aaagcccgcc agttacggcg ggaaacctca
      121 tcctatggga gaacaatgaa taatgaaatt gcggggttat catctcccag tatatccata
      181 ctaacaataa ggttatttac tcaaccaggc ataaacattt tgttttgtgc gtgggaacag
      241 ccttaaggtg taaaggggga ggtggaaata gcaatgagga gtatcagcaa gaatactcgc
      301 cgctttacca caacgtggat gagagggatg aaaaactcaa ggcagagata actctgcctt
      361 gaagataaat gcgcttttac agcgggctta tttcagctct tctgcttccg gtaaggtcac
      421 gttcagctca agaatagaaa tatcgccatc tttttgctca agctgtacgg ttaccatctc
      481 aggatcaatt tgtacgtatt tacaaatgac ctcaagaata tctttacgca actgcggcag
      541 ataatgcggt tctgcatcgc tgcgacggcg ttcagcaaca ataatctgca gccgttcttt
      601 tgcaatgttg gctgtgtttt tcttccgcga gagaaagaaa tcgagtaatg ccataactta
      661 tcctccgaac aagcgtttga ggaagccttt cttctcttct tcaatgaagc ggaaaggacg
      721 ttcttctccc aacagacgtt ctacggtatc tgcgtaggct ttacccgcat cggcgttaat
      781 gtcgagaatg accggttcac cctggttaga ggcgcgcaat actgattgat cctctgggat
      841 cacgccgacg agtttgatgc gcaggatctc cagcacatct tccatgctca gcatgtcacc
      901 tctgcttacg cggcctgggt tatagcgcgt taacagcagg tgctctttaa taggctcttc
      961 gccattttct gcgcggcgtg atttcgacgc cagaatgcct aaaatacggt cagagtcgcg
     1021 tactgaggag acttccgggt tggtggtaat aatggcttcg tctgcaaaat agagtgccat
     1081 taacgcaccg gtttcaatcc ctgccgggga gtcacaaacg ataaattcaa aatccatcgc
     1141 tttcagatca tcaagaactt tggcgacccc ttcacgggtg agggcatctt tatcgcgtgt
     1201 ttgcgatgcc ggcagaatat agagattttc agtacgctta tctttaatta acgcctgatt
     1261 tagcgttgca tcgccctgaa tgacgttgac gaaatcgtaa acgacccggc gttcacaacc
     1321 cataatcagg tcgagattac gcaggccgat atcaaaatct atcacgacag ttttctttcc
     1381 cttctgggcc aaaccagtgg cgatggccgc gctggaggtt gtcttaccaa cacccccttt
     1441 gcccgaagta acaacaataa tgcgtgccat agaaattcct tgttaaaaag ggatcaattt
     1501 aacggttgaa cggtcaaagc gttttcgact aactgcagtc gcgccgcttt gccataaaat
     1561 tctgctggga tttgatcact cagccagtat tcacctgcga tggacaccag ttccgccatc
     1621 aggttcgtac aaaatatttg cgtttcccgg tcaccacttg cccctgccag cgcacgaccg
     1681 cgcatcatgc catagacatg aatgttccca tcggcaatca attcggcccc agcgctaacg
     1741 tggcttgtaa caatcagatc acattgtgga gcataaatac gctgaccgga acgcaccggg
     1801 gtatctatta aacgcgtttt tgtgaccggc gttgtatttt gcgctggagc ctgcggtgtg
     1861 ggagctggac gtggcgcttt ttcctttcct tccgtcagga taggcagccc catcttttca
     1921 atttcggctt taagttgcgc atctttgcag ccacttacgc caataacccg caaaccggtt
     1981 gccgaaaccg ccttatgcat cgctgaccag tttaccgggt cttccagtgc actgacgttg
     2041 agtacaacgg gggcatgttt taaaaatgcg ggggcctgag cgattttgtc ttccagcgcc
     2101 tgatggataa ccttaggttc tgcctcatgc agatgaacca cagataaagt gaagctactg
     2161 cctttaagct cgattggcgt gtttgacatc ctggccttac tcaattagct attaatcatc
     2221 gccagcgcgc gatgatgttc cgaagactat aaggcatgtt atagtctgga ttatattgag
     2281 gcaagtcacc ctcccattta ttcagagtaa aagtctattc tgtgataaat ggcgctgatt
     2341 catagcttaa aaaataccct tgtcaatcaa cccattgccg tcgtactttt gattgttctt
     2401 atttacgctt cctttttccg caccctaatc gtgacagcat ctccagacct gtttaaatat
     2461 ccagtattga ggcaagtgta ttttttcacc acgccaggct ttcttaactt tccatttttt
     2521 gcggcatcat taaagaacag atacccgtta tcttaatatc cgccacagaa ttgctctatc
     2581 atagaaaccg cagaagacgt ctgatacttc tgtcaggtca tcgtaactcg tccaggtcag
     2641 cggttttgat tacggattga tgatgaaatg agcataagtg ttgtacggtt ggattatcag
     2701 gatgtgctat gaatatgatg cgtatttttt atatcggatt gtcaggtgtg gggatgatgt
     2761 tctcatcaat ggcgtctgga aatgacgctg gcggacttca atctccggcg tgcggcgttg
     2821 tttgcgaccc gtatatttgt gtgaactcag atggcatttc cccagagtta acaaggaaat
     2881 atctcggcga aaaagccgct gaaaacttac aatcattaca aggctacgat cccagagaat
     2941 ttacattcgc taacggtgta ttttgcgatg ttaaagaaaa attatgtcgt gatgatcgtt
     3001 attttggtgt ggatggtaag cggagtggaa aaatcaatca aaccaccaca aagatgttat
     3061 ttatgtgtcg tgagtgatgt cttgtttaca ttatgttcta ttcgtcatta acctcttgag
     3121 cgacagagag gagtggggca ttaacgttta tgacggggag agtccccgtc ggttgacatt
     3181 tacttaattt gaatatcgac gttatatttt ttagttttgt ttttacgggc gtcgtttcgg
     3241 gtttgcaaca ctcgcagctc atatttgcca gaagcaggga gtgagtattg tccgtgacta
     3301 tcgagttctg gggaatatct ggataaatca actgaatcat cgattcctgg cccgaagagg
     3361 taagtatcag cgccttcatt agagatactc acatgcactt tctgaccttt tttggcatag
     3421 aaggtatatg tatcgtaatc gtatcccttt atttcgccgg agtactgagc gctgctatgg
     3481 ccttttctga actcaacatt gacattctta cccgcagcaa agctcgtgga ggttagcagt
     3541 gcaagcagca atacagcctt cctgatgctc ttgattttca ttggtagtct cctgttcaga
     3601 atgagtacga tgaactgtta taatataaca atccctaacg ggtgaattcc agtggctttc
     3661 ctgcgttcgg taaaatcacg ttgcggcatt tttgccgggg ggattactta taaaggggca
     3721 tggactcaac aaaccgtaga aatctacagc tggctggctt gtggcgcggg tttcattgat
     3781 gttagcttat gccaaaacct ggcatcttaa agagtaaaag tatgttttgt gtgatttatc
     3841 gaagcagcaa gcgtgaccag acctatttat atgtcgaaaa aaaagacgat ttttcgcgtg
     3901 ttcctgagga actgatgaaa ggttttggtc agcctcagtt agcgatgatt ctgccgctgg
     3961 atgggcggaa gaaactggtc aatgccgata ttgaaaaggt taaacaggca ttaaccgagc
     4021 aaggttacta tttgcagtta ccgccaccac ccgaagattt gctgaagcaa catctttccg
     4081 tcatggggca gaaaacagac gacactaaca aataaccgat atccggcggt ggcattatct
     4141 ttgtcggcgc gggttttcat atccacgata aggtgagggg aacgttatgt atcaacatca
     4201 caactggcaa ggtgcgctgc tggattatcc ggtgagtaaa gtagtctgtg ttggcagtaa
     4261 ctatgccaaa catattaaag agatgggcag cgcagtgccc gaagagccag tgctgtttat
     4321 taaaccagaa acggcactgt gcgatctgcg gcagccattg gcgatcccat ccgatttcgg
     4381 ttcagttcat catgaagtcg aactggcggt gttgattggc gcgacactgc gtcaggctac
     4441 ggaagagcat gtccgcaaag ccattgccgg ttatggcgtg gcgctcgatc tgacattgcg
     4501 tgatgttcag ggaaaaatga agaaagccgg gcagccgtgg gaaaaggcta aagcgtttga
     4561 taactcttgt ccgctttccg ggtttattcc cgcggcggaa tttaccggcg acccgcaaaa
     4621 tacaacgctg agcctgagcg taaacggcga acaacgccag caaggtacga ctgcggacat
     4681 gatccataaa atcgttccgc tgatcgctta tatgagcaag ttttttaccc tcaaggccgg
     4741 tgacgttgtg ttgacaggca cgcctgatgg cgtcggcccg ttgcaaagcg gtgatgagct
     4801 gacagtcact ttcgatgggc attctttgac aactcgcgtt ttgtaatact ttttgccgcc
     4861 tgaaagcggc ggcaaaactt gcatcgctgt gccagactgg ttataaggtg cgttttaacg
     4921 taatggcgga acacctgatg agcgatgtac ctttctggca aagtaaaacc ctggacgaaa
     4981 tgagcgatgc ggaatgggag tcgttgtgtg atggttgcgg tcagtgttgc ctgcataaac
     5041 tgatggatga agacaccgac gaaatctact tcactaacgt cgcctgtcgc cagctcaata
     5101 ttaaaacctg tcaatgtcgg aactacgaac gtcgtttcga gtttgaaccc gactgcatta
     5161 aattaacccg tgaaaatctg ccaacattcg aatggctgcc aatgacctgc gcttatcgtt
     5221 tgctggcgga aggtaaagat ttacctgcgt ggcatccgct acttactggt tcgaaagcgg
     5281 caatgcatgg tgaacgtatc tctgtgcgtc atatcgcagt gaaagaatca gaagtgattg
     5341 actggcagga tcatatctta aataaacctg actgggcgca gtgataaatt taatagatgc
     5401 tgatgggggc tttcttaata tacgtctgga tgctcgccat ttcgtagccc tgtttttgaa
     5461 agcgctctgt cataatgaga gttacccgat accttattat caacaggtaa ctctcaatct
     5521 ttaaaaaacg tctgtgtttt taaatgtgat aaaccttata ccttgagtac atggagagaa
     5581 taatcgctta tcagacttca ggtacctcaa agagtgtctt tttaccgtgt cttttctgat
     5641 actcattaca ggtgttaatc atttttttgg ccgcttcttt tagcaaagaa agcattaaat
     5701 catcataatc aacgtagaat ctggttgttt cagtttccgt ttttatctca ccgatggcgg
     5761 ctatttcggt ggttaatttc aatttggcgg catcgatatc tttattcgct tgtttaaccg
     5821 tgttagacag ggtggtaaag aaattctgca cagattttaa cttgttcttc aattctggaa
     5881 tcagttttcc ttcaactacg cccgcagcaa tagaatagga aatgattaat ccaaatggac
     5941 cggcgacgac accggctgcg gcaccggcat atgcttcctt cctgatttta tctacctgtg
     6001 actggaaata gctgcttttt tctgaaaaat cattggttaa ctggctatct aacgccagca
     6061 gtttcccgga agcgttgttg aaactttgtg agcttaccag cagggatttt tgcgcttcat
     6121 tcagcttcgt gatgccgtca tccagtacct taatgagaat gtctttctgg gcggatgctt
     6181 tcttctcatt gtactcatca aatagcaaaa tatacgctgc gagcaattgc gtcgcaacac
     6241 cacaccattc atacactgtt tgggttgctt caaaatactt atcctggcta tccataagta
     6301 aggttttaat atcgccgact aaaacggagg ctgcctgtga atactcctgt ttaaagcgac
     6361 ttaactcttt tatggtttca tcaaaggtct gccaggggat gacctgatcg agatatttat
     6421 tataaagatc taatgctc
//
LOCUS       DACAOP010000167         6239 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.167, whole genome shotgun sequence.
ACCESSION   DACAOP010000167 DACAOP010000000
VERSION     DACAOP010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6239
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.167"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(89..724)
                     /gene="msrQ"
                     /locus_tag="IT892_004296"
     CDS             complement(89..724)
                     /gene="msrQ"
                     /locus_tag="IT892_004296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HAP3137422.1"
                     /translation="MRLTAKQVTWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQ
                     HFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGV
                     NNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAIL
                     APIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSFFNRLRKQVHNKLSV"
     gene            complement(725..1729)
                     /gene="msrP"
                     /locus_tag="IT892_004297"
     CDS             complement(725..1729)
                     /gene="msrP"
                     /locus_tag="IT892_004297"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HAP3137423.1"
                     /translation="MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHA
                     DLLSWFKGNDRPPAPAGKALEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAA
                     NAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFP
                     LHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLT
                     LMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYG
                     FYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
                     "
     gene            complement(1837..2250)
                     /gene="hiuH"
                     /locus_tag="IT892_004298"
     CDS             complement(1837..2250)
                     /gene="hiuH"
                     /locus_tag="IT892_004298"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HAP3137424.1"
                     /translation="MLKRYLVLSVVTAAFSLPSLVYAAQQNILSVHILNQQTGKPAAD
                     VTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRVVFKTGDYFKKQNLES
                     FFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS"
     gene            2383..3054
                     /gene="hprR"
                     /locus_tag="IT892_004299"
     CDS             2383..3054
                     /gene="hprR"
                     /locus_tag="IT892_004299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor HprR"
                     /protein_id="HAP3137425.1"
                     /translation="MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDD
                     YALIILDIMLPGMDGWQILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPF
                     SFSELLARVRAQLRQHHTLNSTLEISGLRMDSVSQSVSRDNISITLTRKEFQLLWLLA
                     SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSF
                     VAVKK"
     gene            3054..4412
                     /locus_tag="IT892_004300"
     CDS             3054..4412
                     /locus_tag="IT892_004300"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal sensor histidine kinase"
                     /protein_id="HAP3137426.1"
                     /translation="MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTT
                     LINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDILIIHGDSINKIVNRTNVSDDMLN
                     NIPATETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
                     SIIICIVAIVLCSVLSPLLIRTGLREIKKLSGVTEALNYNDSREPVEVSALPRELKPL
                     GQALNKMHHALVKDFERLSQFADDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIA
                     GNIEELENISRLTENILFLARADKNNVLVKLDSLFLNKEVENLLDYLEYLSDEKEICF
                     KVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDTNGYLNIDIASPGTK
                     INEPEKLFRRFWRGDNSRHSEGQGLGLSLVKAIAELHGGSATYHYFNKHNVFRITLPQ
                     RN"
     gene            complement(4520..5371)
                     /gene="hchA"
                     /locus_tag="IT892_004301"
     CDS             complement(4520..5371)
                     /gene="hchA"
                     /locus_tag="IT892_004301"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase HchA"
                     /protein_id="HAP3137427.1"
                     /translation="MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKP
                     YRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMT
                     KFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADIVASLNADSEYAAIFVPGGHGALIG
                     LPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTP
                     EIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQE
                     MLAAYAG"
     gene            complement(5963..6076)
                     /locus_tag="IT892_004302"
     CDS             complement(5963..6076)
                     /locus_tag="IT892_004302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001735381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137428.1"
                     /translation="MNVYTAYQINLLDKSDYVLAHGLNTDDQLAFGIVYQF"
     gene            6175..>6239
                     /locus_tag="IT892_004303"
     CDS             6175..>6239
                     /locus_tag="IT892_004303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP3137429.1"
                     /translation="MKKRNFSAEFKRESAQLVVDQ"
BASE COUNT         1717 a         1305 c         1510 g         1707 t
ORIGIN      
        1 acataaccta atgcgatctg tgtatgccgg atagggcgct cgcgccgcat ccggcaggga
       61 taacgcgtac tttgtcggca atatgaagtt atacagataa tttgttgtga acctgcttgc
      121 gtaaccggtt gaaaaaggaa agcaacttct tataccgtaa ggctaaaagc agtacagcca
      181 gcccagcgta gatgagtggc tgcggtgaaa taatcttcac tgaccataga taatgtattg
      241 gggccaggat cgcgacaaga tagacgaagt tatgcaactg ttgccagtgt ttgccgagtt
      301 ttcgctgcat cgcctgggtt gaagtgaacg ctaaagcaag caaaataacc cagctgataa
      361 tacctaacgt taaataaggc cgggtaatta actccttacc taataacgcc agattattca
      421 cgcccagctc cagcaatgcg taactggtta aatgcagtgt cgcccaggca aagcaccata
      481 agcctaacag gcggcgagtg cgtatcaata acggctgttt tgcgtagcgt gccagaggtg
      541 tgattaacaa ggtcgccagc aaaaatttca gtgcagtgcg accggtaaaa tgctgaatat
      601 ctttcactgg atcggcaccc agtccaccgt gattgatcgc ccagaccagc cagagaaacg
      661 gcaacaatcc ggcaagatgc aggcaaactt tcagccatgt cacctgtttt gctgtcagac
      721 gcattcagaa attctcccgc aaatccaggc cacgatacag cgatgccacc tggtcggcgt
      781 aaccattaaa cagtagcgtt ggctggcgct gtacatcgag gatgccgcct gaaccaataa
      841 atcgttcggt agcctgtgac cagcgcgggt gatcaacatg cggattaacg ttggcgtaaa
      901 aaccgtattc gtcaggcgct gccagattcc aggtggttgg cggacgctcg cgggtcagct
      961 taatactgac gatcgattta atccctttaa agccatattt ccacggcaca atcagtcgca
     1021 ccggcgcgcc attttgtggc ggtaacgcct tgccataaac acctacggtc atcagtgtga
     1081 gcggatgcat tgcttcgtcg agacgcaatc cttcgacata aggatatttc agcccgccgc
     1141 cgataaagcg gtcctgctgg cctggcatct gttccggtgc ataaattgtt tcgaaagcga
     1201 catacttcgc attgctggtg ggttcggcaa gcgccagcaa tttgtgcagc ggaaaaccaa
     1261 tccacggcac caccatcgac cacgcttcca cgcagcgcat acgataaata cgctcttcca
     1321 gcgggaagcg acgggttaaa tcatcgtgat cgagggtcaa tggttttgcc acttcgccgc
     1381 tgattttcag tgtccatgga tcggttttca ggctaccagc attagcggcg ggatcggctt
     1441 tatccagccc gaattcatag aagttgttat aaccggagac tttatctgct ggcgtcagtg
     1501 gcaggttatt ttgccaggcg gcaggcttgc tgaactccag cgcttttccg gcgggggcgg
     1561 gtgggcgatc gttcccttta aaccagctaa gcagatcggc atgcgcagcg tgaggcaaag
     1621 aaagtgcagc tgcgctgatg cccagtgctt ttaacacctg ccgacgcttc ataaagaata
     1681 ccgactcggc cgtaacatct gattctttta aaaattgatt ctttttcata agccatcaca
     1741 ctttttgtcg ttagccagca agagccgttt actgttaatc tgtcagggag tgtcctccct
     1801 aacagtagca gagatctgct tttacatatt tatgcattaa ctgccacgat aggttgaata
     1861 cccatattgg ctaagtaata aaggcacatg ataatgctcg ttcactttat taatatgaaa
     1921 ttcaacgggg atctcaggga agaaactttc aagattttgt ttcttgaaat agtccccggt
     1981 tttaaatacg acacggtaat cgcccgtagt tgcagtttgc tcgggccaca gtgccttaat
     2041 tcgtccatcc ttatctgttt tggcggtatt aagttgtaac cagccgttgt ccgctttctt
     2101 ttcaagagtg actgtcacgt cggcagcggg ttttcctgtt tgctggttca aaatgtgcac
     2161 actaagaatg ttttgttgtg cagcatagac caaagaaggt aatgaaaatg cagccgttac
     2221 tacggagagt actaaataac gctttaacat gtttatatcc ttgtcatgtg aatgagtttt
     2281 gaggatagcg aaaaagcgtc cacggtaacc ttacagcagc attacaattt tgtaatgaac
     2341 caggctgttt ctataacata tgatttatgg catattattt tcatgaagat tttacttatt
     2401 gaagataatc aaaggaccca ggagtgggta acgcaggggc tttccgaagc gggttatgtc
     2461 attgatgccg tttctgatgg cagagatggg ctttatcttg cgcttaagga tgattatgca
     2521 ttgatcattc tggatattat gcttccgggt atggatggct ggcagatctt acaaacgtta
     2581 agaacagcaa agcaaactcc tgttatttgc cttactgcaa gagattctgt cgatgacaga
     2641 gtcagagggc tggacagtgg ggcaaatgat tatctggtaa aacctttttc attttctgag
     2701 ttgctggcaa gggttcgggc acaattaagg caacatcaca ctctgaattc aacattagaa
     2761 atcagtggct taagaatgga ctctgttagt caaagtgtga gcagggacaa tatcagtatt
     2821 acactgacgc gcaaggagtt tcagttactt tggctactgg cctccagagc tggcgagatt
     2881 atccccagaa cggttattgc gagtgaaatt tggggaatca actttgatag tgataccaat
     2941 acggtggacg tcgccattcg caggctccgc gcaaaagttg atgatccttt tcctgaaaag
     3001 ctaatcgcca caatccgggg gatgggctat tcattcgtag cggtaaaaaa ataatgaaaa
     3061 gattatctat aaccgtccgt ttaaccttgc tttttatatt gctgctgtct gttgctggcg
     3121 ctggaattgt atggactctc tataatggcc tggcaagtga gttgaaatgg cgcgatgata
     3181 caacactcat taaccggaca gcgcagatca agcagttgtt aattgatggg gtaaatccag
     3241 atacgttacc tgtgtacttt aaccggatga tggatgttag tcaggatatc ttgatcattc
     3301 atggtgatag catcaacaaa attgttaacc ggacgaatgt cagtgatgac atgttaaata
     3361 acatacctgc tactgagaca atcagcgcag ctggcattta cagaagcatt attaatgata
     3421 cagagataga tgctttacga attaatattg atgaagtttc gccatcatta acggttactg
     3481 tggctaaatt ggcttcagcc agacataaca tgcttgaaca gtataaaatt aatagcatta
     3541 taatttgcat tgtcgccatt gtactttgct cagtattaag tccgctgtta atcagaacgg
     3601 gattacgaga gatcaaaaag ttgagtggtg taacggaagc gctgaattat aacgatagcc
     3661 gggagcctgt tgaggttagc gcattaccga gagaactaaa acctcttggg caggcgttga
     3721 ataaaatgca tcatgcttta gtcaaagatt ttgagcgtct aagtcagttt gctgacgatc
     3781 tcgctcatga acttagaacg cccattaatg cattactggg tcagaatcag gttacgctca
     3841 gtcaaactag aagtatcgct gaatatcaaa aaacaattgc cggtaacatt gaagagctgg
     3901 aaaatatttc gcggttaaca gagaacatac tgtttcttgc ccgggcagat aaaaacaatg
     3961 ttttggtgaa actggactca ctttttctca ataaggaagt cgaaaatttg ttggattatc
     4021 ttgaatacct ttcagacgag aaagagattt gctttaaggt cgagtgcaat cagcaaatct
     4081 ttgcggataa aattttactg caacgaatgt tatcgaatct tattgttaat gccattagat
     4141 attcaccaga aaaatcgcgc attcatataa ccagttttct tgataccaac ggctatctta
     4201 atattgatat cgccagtcct ggaacgaaaa ttaatgagcc tgaaaaactc ttccgtagat
     4261 tttggcgggg agataattcg cgtcattccg aaggtcaggg acttggtctt tctttagtca
     4321 aagcgattgc cgaattgcat gggggaagtg ctacgtatca ctattttaat aagcataatg
     4381 tgttccgaat tacgttaccg caaagaaatt aacatagggc ttcagtacgc cataaatcaa
     4441 ccatgaaaaa acgcagccac gtcgtgagta ttaacgtggc tgcgattgat tatgcgctta
     4501 cattcatacg taacagggat taacccgcat aagctgccag catttcctgc gccgccagtt
     4561 tacccaacgc attcgctgcg aaaggactgt cgccggtgag aactttacgg tccttatgta
     4621 ctcgcccggt gatgtcgtca ttaataatgt tcatgcccat tttcttcagc tcttcgccga
     4681 agtaccaggt gagatgaccc ggcatatagc ctatctctgg cgtttgtttg tctgcggcgt
     4741 ctgggaatgc gcaaatggaa taaccattca gtgggttatc gccgtggcga agcgccagaa
     4801 aagccgccgg gccgtggcaa agggagataa caaaacggtc atttttgatt gcccactgca
     4861 aagcagcagc cacgtcctgg ctttctggta aaccaataag tgcgccatga ccaccaggaa
     4921 caaagattgc tgcatattcg ctgtctgcgt tgaggctggc gacaatatcc gcgagttttt
     4981 tcggattgcg gaacaacgat ttatgctgct caaagaatgg cattactttt tcatctttgt
     5041 gcggcatagc ccagtattca aacttggtca tcagaccgga aatggtcgcc acttcgaatt
     5101 cgaaacctgc agcatggaga tgatacaacg gcagcaacgt ttcaatcgga tggttaccgg
     5161 tcgagaacag ttttccgtta tcggtcggca aataacgttc gtccgcggcg atcaccagaa
     5221 ttttatgttt accgcgatac ggttttggat agtccacgcc atcaagatca gagacaggac
     5281 tggtatattg gctaagcgaa tattctgaag ggaagaatgc attatcttca gcaatatcga
     5341 cctgcggatt tttacttgtt tgaacagtca tagtgtattc cttattgttg cttagttagg
     5401 gtagtcacta tatttgcgac tgagctggtc gctattttta accagtctgg aaaattgagt
     5461 caatatatcg aaagcggtag tctgcgggtg taagtatgta atgatgatgc tgcactggtg
     5521 ttgaatatta ttcacgccaa attttcctta ttgagcaacg tcgtcgcaag tggcctcaat
     5581 gattttagac cattatcaga gatgcggggc ggagggaaga gatttagtgc tgtggaatat
     5641 tgtggtgctg atgaatattt atatcccgga ttggtagaga aaaagcttat ttcatgcact
     5701 atttttgcaa atatttctat atgggaggcg tgtttgttgc ggattaatac ataaagaaat
     5761 gtatttggag tgttggctgg aagagtagct ggtagagata ttgtgccagg aggggcaggg
     5821 taaggtgctg tatcgatatg ctttggcaat tgcgtgtgcc gcagatggag atgaaatgcc
     5881 aataaaaaag cctgagttcg atgagggacg aactcaggct agtgttatgt tttacagtaa
     5941 cacgccgcgg cgcgttggct gattagaact ggtagacgat accaaatgcg agttggtcgt
     6001 cggtgttcag tccatgagcg agaacataat cactcttatc aagcaggttg atctgataag
     6061 cggtatatac gttcatgttc ttattgaagt aataccaggt actgaagtgg tttactgaat
     6121 ttggccacct gaacagaggt gatatgctca cctcagaaca acacaggtgc cataatgaaa
     6181 aaaagaaatt tcagcgcaga gtttaaacgc gaatccgctc aactggtcgt tgaccagaa
//
LOCUS       DACAOP010000168         6200 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.168, whole genome shotgun sequence.
ACCESSION   DACAOP010000168 DACAOP010000000
VERSION     DACAOP010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6200
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.168"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(85..900)
                     /gene="sul2"
                     /locus_tag="IT892_004304"
     CDS             complement(85..900)
                     /gene="sul2"
                     /locus_tag="IT892_004304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /protein_id="HAP3137430.1"
                     /translation="MNKSLIIFGIVNITSDSFSDGGRYLAPDAAIAQARKLMAEGADV
                     IDLGPASSNPDAAPVSSDTEIARIAPVLDALKADGIPVSLDSYQPATQAYALSRGVAY
                     LNDIRGFPDAAFYPQLAKSSAKLVVMHSVQDGQADRREAPAGDIMDHIAAFFDARIAA
                     LTGAGIKRNRLVLDPGMGFFLGAAPETSLSVLARFDELRLRFDLPVLLSVSRKSFLRA
                     LTGRGPGDVGAATLAAELAAAAGGADFIRTHEPRPLRDGLAVLAALKETARIR"
     gene            complement(1560..1964)
                     /locus_tag="IT892_004305"
     CDS             complement(1560..1964)
                     /locus_tag="IT892_004305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication initiation protein"
                     /protein_id="HAP3137431.1"
                     /translation="MLHVAGEKRQHRRVSRICDTGDIPLPRSLTRYARSFGCGERYRL
                     TDGDGNFLEDTRKTLSKEEIRPRRSRFSIGSAPLTSIAKSDAQISGGETRQDYKDPRR
                     FPLVAPSCALLFLPFGLPVSFRCYGRGFSFHA"
     gene            complement(2983..3471)
                     /locus_tag="IT892_004306"
     CDS             complement(2983..3471)
                     /locus_tag="IT892_004306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011161230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="HAP3137432.1"
                     /translation="MFCCYNTVHTGDTVTFMAWHTVQETLKLTGKSRSQLYRDMAKGL
                     VSYRTGKNDRREFETSELIRAYGELRTSETPKRHKEGHSKSVVSQAENAQLDVIQQKL
                     DALQQTVTLMLEDKMAREAENRLRNEEREQLQAEISRLADALAQEKKRGFWSRLFRSG
                     SE"
     gene            3641..4030
                     /locus_tag="IT892_004307"
     CDS             3641..4030
                     /locus_tag="IT892_004307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137433.1"
                     /translation="MSTELNSGTVGGFGHMGPNDPYNDGHSGSGSSGGSFNGGGNGGH
                     DNSSGSSYTASFGLITGRHPITVPGTKNINSVDLSAVINNIIHHEGARNNMYLDTANN
                     VRVGVTGTGWQCLATAGISAEGKRTFR"
     gene            4074..4613
                     /locus_tag="IT892_004308"
     CDS             4074..4613
                     /locus_tag="IT892_004308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HAP3137434.1"
                     /translation="MPHVAARTASRDRDTGRYQSHRPEQTLLYQIVDEYYPAFAALMA
                     EQGKELPGYVQREFEEFLQCGRLEHGFLRVRCESCHAEHLVAFSCKRRGFCPSCGARR
                     MAESAALLVDEVLPEQPMRQWVLSFPFQLRFLFGVVCGKGRNPTLRLWPAIFSGEIDV
                     FPGDRRSRLISSMTSVAPA"
     gene            complement(4585..5421)
                     /locus_tag="IT892_004309"
     CDS             complement(4585..5421)
                     /locus_tag="IT892_004309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="HAP3137435.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLK
                     PIEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATE
                     IAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMM
                     SNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDP
                     RRIAQMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQT
                     SY"
     gene            complement(5421..>6200)
                     /locus_tag="IT892_004310"
                     /note="aph(3'')-Ib"
     CDS             complement(5421..>6200)
                     /locus_tag="IT892_004310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3'')-Ib"
                     /protein_id="HAP3137436.1"
                     /translation="GESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASRRGELAGER
                     DRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAWPSMGQQLG
                     AVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLLARVERELP
                     VRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLALMIANAEE
                     NWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
BASE COUNT         1432 a         1616 c         1642 g         1510 t
ORIGIN      
        1 aaaaaaaata ttagttcgat ttaatggagg ttccttcagt tttctgatga agcgcgaata
       61 tagagaaata tcccgaatgt gcagttaacg aattcttgcg gtttctttca gcgccgccaa
      121 taccgccagc ccgtcgcgca aggggcgcgg ctcgtgtgtg cggatgaagt cagctccacc
      181 tgcggcggcg gcaagctctg cagcgagtgt cgcggccccg acatcccccg gaccacggcc
      241 tgtgagcgcg cgcagaaagg atttgcgcga aacagacaga agcaccggca aatcgaagcg
      301 cagccgcaat tcatcgaacc gcgccagcac cgagagcgag gtttcgggag cagcccccag
      361 aaaaaacccc atgccgggat caaggacaag gcggttgcgt ttgataccgg cacccgtcag
      421 cgccgcgatg cgcgcgtcaa agaacgccgc aatgtgatcc atgatgtcgc cagcgggtgc
      481 ctcgcgccga tctgcctgcc cgtcttgcac cgaatgcata acgacgagtt tggcagatga
      541 tttcgccaat tgcggataga acgcagcgtc tggaaaaccg cgaatatcat tgagataggc
      601 cacaccacgc gacaaggcat aggcttgcgt cgcgggttga taactgtcga gcgagacggg
      661 aatgccatct gccttgagcg cgtccagcac cggcgcgata cgcgcgattt ctgtgtcgga
      721 cgaaacaggc gcggcgtcgg gattgctgga tgccggaccg aggtcgatca catctgcccc
      781 ctcggccatc agcttacgcg cctgcgcaat ggctgcgtct ggcgccagat accggcctcc
      841 atcggagaaa ctgtccgagg ttatgttgac gatgccgaaa atgatgagcg atttattcat
      901 gggggcttct ataataataa taatcgagca tgagtctcat acggatgctc gggtcgaaag
      961 ggaatcccca ggcgagtaac ctgtttgcgg tgatccgttt catgatgatg tatctgtagc
     1021 attttggaaa taaatatatc atctctcaat aagtagatat atttatcttt tttgcttctt
     1081 tggtgctgca agtcaccaat acgagggaaa cctgttacgg agcggtttaa ccgtaatcaa
     1141 cagtgactgg tgtcatgttc ggaagattaa ttgatagtaa tctacaaagg atcttcttga
     1201 gatccttttc aatgaatcgt aatctcttgc tctgtaaacg aaaaaaccgc ctggggaggc
     1261 ggtttgttcg aaggttaagt cagttgggga actgcttaac ccggtaacag ggttcacgag
     1321 accgccatta ccaaaactgt tctttcagtg tagccgcagt caggcctcta cttcaagacc
     1381 tcttaatcta tcttctcgtg cactcctgtt actaatggct gctgccagtg gcgttttgtc
     1441 gtgtctttcc gggttggact caagttgata gttaccggac aaggcgcagc ggtcggactg
     1501 aacggggggt tcgtgcatac agtccagctt ggagcgaact gccttcacgg aactgagtgt
     1561 caggcgtgga atgagaaacc gcggccataa cagcggaatg acaccggtaa accgaaaggc
     1621 aggaacagga gagcgcacga gggagctacc agggggaaac gcctgggatc tttatagtcc
     1681 tgtcgggttt cgccaccact gatttgagcg tcagattttg cgatgcttgt caggggggcg
     1741 gagcctatgg aaaaacggct tcgccgtggc cttatctctt ctttgctaag tgtcttcctg
     1801 gtatcttcca ggaaatttcc gtccccgtcc gtaagccggt accgctcgcc gcagccgaac
     1861 gaccgagcgt agcgagtcag tgagcgagga agcggaatat ctcctgtatc gcatattctg
     1921 ctgacgcgcc ggtgctgcct tttttctcct gccacatgaa gcacttcact gattttcgca
     1981 atcgtggcaa catagtaagc cagtatacac tccgctagcg ctacatgact ggttcagggc
     2041 tgcgccccga aacccgctaa caacctctca gctactggat atcaccccat gccatctgaa
     2101 tatgatgaac aactggattc gactgatacg cagcttcccg gcgaatatga cctttttgat
     2161 ttaatggcgc aggttactga agagaacctg catgcccctg tggattttgg gtcgcctgtc
     2221 ggccgggaag cgttatagct ttttcgcttg cccgcgtacg tggtaatact ccggtattac
     2281 cttttatttc tttattttca tgtaattaca gtggattttt aatacccggg tattactcgt
     2341 gaaaacgaaa tattcctttt ttttctttta attcatgcag ttgcgatgaa aatcgcggct
     2401 gcgttaggtg tatgaccatt ttgaggttga aaaataatca accatggcgg gtgatttacg
     2461 caggttaagg ggagatcgtg acaaaaaaag cgttcctcac tgtatcgttc atgcctgcat
     2521 gaacgggtta ttcttcctga ctacagaatt acatcgctcc ttcagttcat acatcacttt
     2581 tacatcactt atacatcact tttacatcat tccttcagct catacgtcac tttcatcctc
     2641 tgtgccattt gtacatcacc cccttcctga acgtgctgac agcgggtttt ccggctgcgc
     2701 cggcaacgct tcacggccac gcaataaatt gcgtccccgt tcaccgtttt cggatgggaa
     2761 gaacgccgga aacaggactt accccggctg aatggtgtga atttccgcgc tatgcacttg
     2821 tgcgcatact catgcatgcc gtaaaaacag agcctgcgcg tttctggcgg gttttcgggt
     2881 ggtttgttgc ctgttttacc ggtttcccgt cagaaacgcc ctgagggcct ctcaggcggt
     2941 gctgataaca gatgttatgg taaatcagag tcacctgcac tgttactctg aaccggagcg
     3001 aaacagccgc gaccagaatc cccgcttttt ttcctgtgcc agcgcgtcag ccagacggct
     3061 aatttcggcc tgtagttgtt ccctctcctc atttcgcagg cggttttctg cttcccgcgc
     3121 catcttgtct tcaagcatta gggtaacagt ctgctgcaga gcgtccagtt tctgctgaat
     3181 gacgtctagc tgagcatttt ccgcctggct aacgacagat ttggagtgtc cctccttgtg
     3241 cctttttggt gtctcagaag tgcgcagctc gccataggcc cgaatcagtt cactggtctc
     3301 gaactcccgg cgatcatttt ttcctgtgcg atagctgaca aggcctttag ccatgtcacg
     3361 atataattgc gagcgcgact ttcctgttaa tttcagtgtc tcttgaactg tgtgccatgc
     3421 cataaaagtg acagtgtctc ctgtgtgtac cgtattgtaa cagcagaaca tattactgtt
     3481 ttaacacaaa aggtctgagg ctgcccgtga ggcgtgaaaa atacacaaaa aacctgttga
     3541 cggtgtggtt ttgacgggcg tagtatttcg aatactgtat ataaacacat tgttataaat
     3601 acagtttttg ctgtttttaa aagtcaaaga ggataatttt atgagtacag agttaaatag
     3661 cggtactgtc ggtggttttg gtcacatggg accaaatgac ccctacaatg atggtcatag
     3721 cggctctgga agttcgggag gtagttttaa cggtggtggt aatggtggcc atgataatag
     3781 tagtggttca tcttatactg catcctttgg tctcatcact ggccgacacc cgataactgt
     3841 cccaggtacg aagaatatta attctgtcga tctttctgct gtcattaata acattataca
     3901 tcatgaaggt gcacgcaata acatgtacct agatactgcg aacaatgtaa gagtgggagt
     3961 gacgggcact ggctggcaat gtctagcaac ggcaggcatt tcggctgagg gtaaaagaac
     4021 tttccgctaa gcgatagact gtatgtaaac acagtattgc aaggacgcgg aacatgcctc
     4081 atgtggcggc caggacggcc agccgggatc gggatactgg tcgttaccag agccaccgac
     4141 ccgagcaaac ccttctctat cagatcgttg acgagtatta cccggcattc gctgcgctta
     4201 tggcagagca gggaaaggaa ttgccgggct atgtgcaacg ggaatttgaa gaatttctcc
     4261 aatgcgggcg gctggagcat ggctttctac gggttcgctg cgagtcttgc cacgccgagc
     4321 acctggtcgc tttcagctgt aagcgtcgcg gtttctgccc gagctgtggg gcgcggcgga
     4381 tggccgaaag tgccgccttg ctggttgatg aagtactgcc tgaacaaccc atgcgtcagt
     4441 gggtgttgag cttcccgttt cagctgcgtt tcctgtttgg ggtcgtttgc gggaaggggc
     4501 ggaatcctac gctaaggctt tggccagcga tattctccgg tgagattgat gtgttcccag
     4561 gggataggag aagtcgcttg atatctagta tgacgtctgt cgcacctgct tgatcgcggc
     4621 cgcgatagct agatcgcgtt gctcctcttc tccatccgcg ttccaagctg cggaaaggca
     4681 cccataagcg tacgcctggt cgagcaggcg acgcggatcg acgtccagcg cacgagagaa
     4741 tgcgtccgcc atctgtgcaa tgcgtctagg atcgagacaa aggtcgtctc tgtcagccgg
     4801 atcgtagaac atattggcgg cgccaaagcc cacttcaccg accagaccga cgggatctat
     4861 caccagccag ccgcgactgg agaacatgat gttttcatga tgcagatcgc catgtagccc
     4921 acgcagttcc gaggcattgc tcatcatttg atcggctata atcgccgcgt ggacgtagtc
     4981 agtttgacaa cctgcgtttt gatcatcgcg cgcccgctga aacaaagctg caaagcgatc
     5041 ccggatcggg agaagggcag aaggcagggg ttcctcagat gcggcataca gcttcgccat
     5101 tagttccgct gcaatttcgg tcgcctggta gtcgccgtgc tcggcaacga tgtgagagag
     5161 cattcgctcc ccggcatatt cgagcaacat cagattgttc tcacgaccga gcaaccggac
     5221 tgctcccctc ccattgcgcc ataccagata gtcggccccg cgcagttcat cagcaatgtc
     5281 ttctataggt ttcaatccct tgacgattgc aggagtcccg tctggcaatg aaactttcca
     5341 aacgaggctg gaaaaggtgt ccgcaatgag aacaggttgc gaaacgtgcc aatgagcagg
     5401 aaaaacaggc ggcatgaaca tcaaccccaa gtcagagggt ccaatcgcag atagaaggca
     5461 aggcgttcgc ggtcgggggc ttcgatcccc aatacattga ataggacagc gaaggcgcgc
     5521 tctgcttcat ctggcgctgc ccagttctct tcggcgttag caatcatgag tgccaaatcg
     5581 gcatagcgat ctgctgttcc gagccgccca aggtcgatca gacccgtgca ttgaagagtt
     5641 ttagggtcca ccatgaagtt cggcatgcag ggatcaccat ggcaaacaac catatcggtg
     5701 cgctcttggt cgagccgcac cggtagctct cgttcgacac gagccaaaag atcgagctgc
     5761 ggcgtactct tgtcctcgtc cggtaagaag tcgggattga cggcattgcg ggacaccaca
     5821 tcaacggcgc gtccgaacat tcgcgacagc ctgcgctcaa acggacattg atcaaccgat
     5881 aggctgtgaa cagcgccaag ttgctgcccc attgacggcc acgctttgag caaatccgct
     5941 ccagacagat cagccgccgg tactcccgga attgccgtta tcaccaagca tgcaccctcc
     6001 tgttcctcct gccagttgat gacctcgggg caagccacac ctcgaccttt gagccaaatg
     6061 aggcggtcac gctctccagc gagctcaccg cggcgggaag caggtgcgat tttcgcgaag
     6121 gcatgcccgt caccacgtcg aaaaacaaaa tcaccagatt ctccgcctct gacaggcaac
     6181 cagtcagaat gcgattcacc
//
LOCUS       DACAOP010000169         6116 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.170, whole genome shotgun sequence.
ACCESSION   DACAOP010000169 DACAOP010000000
VERSION     DACAOP010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6116
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.170"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            44..2110
                     /gene="ppk1"
                     /locus_tag="IT892_004311"
     CDS             44..2110
                     /gene="ppk1"
                     /locus_tag="IT892_004311"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HAP3137437.1"
                     /translation="MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSN
                     NLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEM
                     ARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVE
                     IIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYD
                     ALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVL
                     REKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHIWFDKAQFRNGFD
                     AIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHN
                     GKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVV
                     RYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQ
                     NSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLVRGM
                     CSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEV
                     ATPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIK
                     SLEQPE"
     gene            2115..3656
                     /gene="ppx"
                     /locus_tag="IT892_004312"
     CDS             2115..3656
                     /gene="ppx"
                     /locus_tag="IT892_004312"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HAP3137438.1"
                     /translation="MPIHDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQR
                     VHLADGLGPDNMLSEEAMTRGLNCLSLFAERLQGFSPASVCIVGTHTLRQALNATDFL
                     KRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPI
                     LVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQFRIQGWNVAMGASG
                     TIKAAHEVLMEMGEKDGIITPERLEKLVKEVLRHRNFASLSLPGLSEERKTVFVPGLA
                     ILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTASSLANQYHIDSEQAR
                     RVLDTTMQMYEQWREQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQNS
                     DLPGFNQEQQLMMATLVRYHRKAIKLDDLPRFTLFKKKQFLPLIQLLRLGVLLNNQRQ
                     ATTTPPTLTLITDDSHWTLRFPHDWFSQNALVLLDLEKEQEYWEGVAGWRLKIEEEST
                     PEIAA"
     gene            complement(3695..5938)
                     /gene="pdeF"
                     /locus_tag="IT892_004313"
     CDS             complement(3695..5938)
                     /gene="pdeF"
                     /locus_tag="IT892_004313"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeF"
                     /protein_id="HAP3137439.1"
                     /translation="MKLNATYIKIRDKWWGLPLFLPSLILPIFAHINTFAHISSGEVF
                     LFYLPLALMISMMMFFSWAALPGIALGIFVRKYAELGFYETLSLTANFIIIIILCWGG
                     YRVFTPRRNNVSHGDTRLISQRIFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMP
                     FNLGTLINYQALLVGNLIGVPLCYFIIRAVRNPFYLRSYYSQLKQQVDVKVTKKEFAL
                     WLLALGALLLLLCMPLNEKSTIFSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMI
                     SIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQRAVARRIQRLAYVDP
                     VVHLPNVRALNRALRDAPWSALCYLRIPGMEMLVKNYGIMLRIQYKQKLSHWLSPLLE
                     PGEDVYQLSGNDLALRLNTESHQERITALDSHLKQFRFFWDGMPMQPQIGVSYCYVRS
                     PVNHIYLLLGELNTVAELSIVTNAPENMQRRGAMYLQRELKDKVAMMNRLQQALEHNH
                     FFLMAQPITGMRGDVYHEILLRMKGENDELISPDSFLPVAHEFGLSSSIDMWVIEHTL
                     QFMAENRAKMPAHRFAINLSPTSVCQARFPVEVSQLLAKYQIEAWQLIFEVTESNALT
                     NVKQAQITLQHLQELGCQIAIDDFGTGYASYARLKNVNADLLKIDGSFIRNIVSNSLD
                     YQIVASICHLARMKKMRVVAEYVENEEIREAVLSLGIDYMQGYLIGKPQPLIDTLNEI
                     EPIRESA"
BASE COUNT         1645 a         1486 c         1489 g         1496 t
ORIGIN      
        1 tatccaggca gtgtcccgtg aataaaacgg agtaaaagtg gtaatgggtc aggaaaagct
       61 atacatcgaa aaagagctca gttggttatc gttcaatgaa cgcgtgcttc aggaagcggc
      121 ggacaaatct aacccgctga ttgaaaggat gcgtttcctg gggatctatt ccaataacct
      181 tgatgagttc tataaagtcc gcttcgctga actgaagcga cgcatcatta ttagcgaaga
      241 acaaggttcc aactctcatt cccgccattt actgggcaaa attcagtccc gggtgctgaa
      301 agccgatcag gaattcgacg gcctctacaa cgagttgttg ctggagatgg cgcgcaacca
      361 gatcttcctg attaatgaac gccagctctc cgtcaatcaa caaaactggc tgcgtcatta
      421 ttttaagcag tatctgcgtc agcacattac gccgatttta atcaatcctg acactgattt
      481 agtgcagttc ctgaaagatg attacaccta tctggcggtg gaaattatcc gtggcgatac
      541 catccgttac gcgctgctgg agatcccatc agataaagtg ccgcgctttg tgaatttacc
      601 gccagaagcg ccgcgtcgac gcaagccgat gattcttctg gataacattc tgcgttactg
      661 ccttgatgat attttcaaag gcttctttga ttatgacgcg ctgaatgcct attcaatgaa
      721 gatgacccgc gatgccgaat acgatttagt gcatgagatg gaagccagcc tgatggagtt
      781 gatgtcttcc agtctcaagc agcgtttaac tgctgagccg gtgcgttttg tttatcagcg
      841 cgatatgccc aatgcgctgg ttgaagtgtt acgcgaaaaa ctgactattt cccgctacga
      901 ctccatcgtc cccggcggtc gttatcataa ttttaaagac tttattaatt tccccaatgt
      961 cggcaaagcc aatctggtga acaaaccact gccgcgttta cgccacattt ggtttgataa
     1021 agcccagttc cgcaatggtt ttgatgccat tcgcgaacgc gatgtgttgc tctattatcc
     1081 ttatcatacc tttgagcatg tgctggaact gctgcgtcag gcttcgttcg acccgagcgt
     1141 actggcgatt aaaattaaca tttaccgcgt ggcgaaagat tcacgcatca tcgactcgat
     1201 gatccacgcc gcacacaacg gtaagaaagt caccgtggtg gttgagttac aggcgcgttt
     1261 cgacgaagaa gccaacattc actgggcgaa gcgcctgacc gaagcaggcg tgcacgttat
     1321 cttctctgcg ccggggctga aaattcacgc caaactgttc ctgatttcac gtaaagaaaa
     1381 cggtgaagtg gtgcgttacg cacacatcgg gaccgggaac tttaacgaaa aaaccgcgcg
     1441 tctttatact gactattcgt tgctgaccgc cgatgcgcgc atcaccaacg aagtacggcg
     1501 ggtgttcaac tttattgaaa acccataccg cccggtgaca tttgattatt taatggtgtc
     1561 gccgcaaaac tcccgccgcc tgttgtatga aatggtggac cgcgaaatcg ccaacgcgca
     1621 gcaagggctg cccagcggta tcaccctgaa gctaaataac cttgtcgata aaggcctggt
     1681 tgatcgtctg tatgcggcct ccagctccgg cgtaccggtt aatctgctgg ttcgcggcat
     1741 gtgttcgctg atccccaatc tggaaggcat tagcgacaac attcgtgcca tcagtattgt
     1801 tgaccgttac cttgaacatg accgggttta tatttttgaa aatggcggcg ataaaaaggt
     1861 ctacctttct tccgccgact ggatgacgcg caatattgat tatcgtattg aagtggcgac
     1921 accgctgctc gatccgcgcc tgaagcagcg ggtgctggac atcatcgaca tattgttcag
     1981 cgatacggtc aaagcacgtt atatcgataa agaactcagt aatcgctacg ttccccgcgg
     2041 caatcgccgc aaagtacggg cgcagttggc gatttacgac tacatcaaat cactcgaaca
     2101 acctgaataa ccctatgcca atacacgata aatcccctcg tccgcaggag tttgctgcgg
     2161 tcgatcttgg ttcaaacagt tttcacatgg tcattgcccg tgtggtagat ggtgccatgc
     2221 agattattgg ccgcctgaaa cagcgggtgc atctggcgga cggcctgggg ccagataata
     2281 tgttgagtga agaggcaatg acgcgcggtt taaactgtct gtcgctgttt gccgaacggc
     2341 tgcaagggtt ttctcctgcc agcgtctgta tagttggcac ccatacactg cgtcaggcgc
     2401 tgaacgccac tgactttctg aaacgcgcgg aaaaggtcat tccctacccg attgaaatta
     2461 tttccggtaa tgaagaagcc cgtctgattt ttatgggcgt ggaacatacc caaccggaga
     2521 aaggtcgcaa actggttatt gatattggcg gcggatctac ggaactggtg attggtgaaa
     2581 atttcgaacc gattctcgtt gaaagccgcc ggatgggttg tgtcagcttt gcccagcttt
     2641 acttccctgg cggggtcatc aataaagaga attttcagcg cgctcgtatg gcggcagcac
     2701 aaaaactgga aactttaacc tggcaattcc gtattcaggg ctggaacgtg gcaatgggcg
     2761 cttccggtac cataaaagcc gcccatgaag tgttaatgga aatgggcgag aaagacggga
     2821 taattacccc ggaacgtctg gaaaaactgg taaaagaagt tttacgtcac cgtaatttcg
     2881 catcgctgag tttaccgggt ctttccgaag agcggaaaac agtcttcgtt cctggactgg
     2941 cgattttatg cggtgtgttt gatgctttag ccatccgtga actgcgcctt tctgacgggg
     3001 cgttacgcga aggcgtactg tatgaaatgg aaggacgttt ccgtcatcag gatgtgcgta
     3061 gtcgcaccgc cagcagcctc gccaaccagt atcacatcga cagtgaacag gcccgacggg
     3121 tgctggatac cactatgcaa atgtacgaac agtggcggga acagcaaccg aagctggcgc
     3181 atccgcaact ggaggcgcta ctgcgatggg ccgccatgct gcatgaggtc gggttgaata
     3241 tcaaccacag cggtttgcat cgccactccg cttatattct gcaaaacagc gacttgccgg
     3301 gttttaatca ggaacagcag ttgatgatgg cgacgctggt gcgctatcac cgtaaagcga
     3361 ttaagctcga cgatctgccg cgctttacct tgtttaagaa gaaacagttc ctgccactga
     3421 ttcagctatt gcgccttggc gtattactca ataatcaacg tcaggcaacc accacaccgc
     3481 caacattgac gctgattacc gatgacagtc actggacact gcgttttccg catgactggt
     3541 ttagtcagaa tgcgctggta ctgcttgatc tggaaaagga gcaagaatac tgggaaggcg
     3601 tggctggctg gcggttgaaa attgaagaag aaagtacacc agaaatcgcc gcttaatgct
     3661 ttgcgggccg acaagaaatg tcggcccgca ttattcaggc actttcgcga atgggttcga
     3721 tttcattcag cgtatcaatt aacggttgcg gcttaccaat aagataaccc tgcatataat
     3781 cgatccccaa agagagcacc gcctcgcgga tctcttcgtt ttcaacgtac tctgccacta
     3841 cccgcatttt cttcattcgc gccaggtggc aaatcgacgc cactatctga taatccagac
     3901 tatttgacac aatattgcgg ataaaactgc cgtcaatttt aagcagatcg gcattcacat
     3961 ttttaagccg cgcatagctg gcgtagccgg tgccgaaatc atcaatcgca atctggcagc
     4021 ctaattcctg aagatgctgc aaggtgattt gcgcctgctt aacattggtc agagcattac
     4081 tttcggtgac ttcaaaaata agttgccacg cttcaatctg atatttagcc agcagctgac
     4141 tgacttcaac gggaaaacga gcctgacata ccgaggttgg cgacagatta atggcaaaac
     4201 ggtgagcggg catcttcgct ctgttttcag ccataaattg cagcgtatgt tcaatgaccc
     4261 acatgtcgat actcgacgat aaaccaaatt cgtgcgcgac cggcaagaag ctgtcggggc
     4321 tgatcagttc atcattctca cctttcatac gcagaagaat ttcatggtag acatcgccac
     4381 gcataccggt aatcggctgg gccatcagga aaaaatggtt gtgttccagc gcctgctgta
     4441 gccgattcat catcgcgact ttatctttca attcgcgttg caaatacatt gccccgcgac
     4501 gctgcatatt ttcaggggcg ttggtcacga tggaaagctc ggcgaccgta tttagctctc
     4561 ccagcagcag gtagatatga ttcactggcg agcgcacata gcagtaactg acgccaatct
     4621 gcggttgcat cggcattcca tcccaaaaga aacgaaattg cttgagatgg ctatccagtg
     4681 cggtaatgcg ctcctggtgc gattctgtat tcagtcgcag cgcgagatcg ttacccgaaa
     4741 gctgataaac atcctcaccc ggttccagca agggtgacag ccagtgagaa agtttttgct
     4801 tgtattgaat ccgcagcatg atgccatagt tcttaaccag catttccatg ccagggatgc
     4861 gtaaataaca aagcgcagac cagggggcat cacgcaacgc gcgattcagg gcgcgaacat
     4921 ttggcagatg aaccaccggg tccacatacg caagccgctg aatgcgtctg gctaccgctc
     4981 tctgacgggt tgccagtaca gccatataat tgacaataaa agagaatacc agataactgg
     5041 aggaggttat ggtcagctgc gtggtatagc caggataaat gggaatgtaa ttttgatagc
     5101 tgtggatgct gatcatcaac acgaccgccc agagcagcga aattagctta taaccatagc
     5161 gcatcgctcc ccacatcatc aggggcagca ataatgacaa ggtatagttg gtgctaaaaa
     5221 ttgtgctttt ttcatttaac ggcatgcata acagcagcag taaagcacct aatgccagta
     5281 gccagagtgc gaactctttt ttggtgactt ttacatcaac ctgctgtttt aattgcgaat
     5341 aataactacg taaataaaac ggatttcgca ctgcacgaat gatgaagtag cacagcggga
     5401 caccaatcag attgcccacc agtaaggcct gataattgat taaggtcccg aggttaaaag
     5461 gcatgacgcc gaccagattt tctctgctcg ccagtaatcc tacaaacgca gcaaactgga
     5521 aaagtatcag aaacagcgtt gcaggaaaca caatctgcca gaatatacgc tgggaaatta
     5581 aacgggtatc accatgtgaa acgttgttac gccggggagt aaagaccctg taaccgcccc
     5641 aacagagaat gataatgata ataaaattag ccgttaatga gagcgtttcg taaaaaccca
     5701 gctctgcata tttgcggaca aaaatcccta aggcgatccc tggcaatgcc gcccagctga
     5761 aaaacatcat catgctgatc atcagagcca gaggcagata aaagagaaaa acctcaccgg
     5821 aagaaatatg cgcgaaagta ttaatgtggg cgaaaatggg caagattaaa gaaggcagga
     5881 acagcggaag cccccaccat ttatcacgta tttttatata agttgcattc agtttcatag
     5941 atgctcagca gaatccccca catcctgaag gaggtgtatt cagacaggca tcccacctga
     6001 cttcgaatga tgattattca tcactataga gagcattgat tctaagtgtc atatgaaagt
     6061 tccaattgat atatatcaaa caaaataacc ctgattaatg aattattacg tttatc
//
LOCUS       DACAOP010000170         5991 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.171, whole genome shotgun sequence.
ACCESSION   DACAOP010000170 DACAOP010000000
VERSION     DACAOP010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5991
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.171"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            168..809
                     /locus_tag="IT892_004314"
     CDS             168..809
                     /locus_tag="IT892_004314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016153623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HAP3137440.1"
                     /translation="MNNLNSLQEIARAIRNLIRTGIVTDVDPVEGLCRVQTGGMQTTW
                     LNWLTCRAGRSRVWWAPSVGEQVLILAIGGELDTAFVLPGIFSDDHPAPSASSDAFHV
                     TFPDGAVIEYEPENGALTVSGIKTADVTASESITAIVPVVLVKAETRITLDTPEVVCT
                     NKLITGTLEVKKGGTMSGNIEHTEGKFTSNGVQVDAHDHGGVEPGGNWTKGVK"
     gene            806..1156
                     /locus_tag="IT892_004315"
     CDS             806..1156
                     /locus_tag="IT892_004315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017382989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate assembly protein"
                     /protein_id="HAP3137441.1"
                     /translation="MTVRYLGMNSQTGLSISEVEHIRQSVRDILVTPVGSRVMRREYG
                     SLLSALIDQPQTPALRLQIMAACYSAIQRWEPRVSLSTITVERGEDDGAMYVDMTGTR
                     SASGQPFSITLPLS"
     gene            1162..2070
                     /locus_tag="IT892_004316"
     CDS             1162..2070
                     /locus_tag="IT892_004316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001121472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate assembly protein"
                     /protein_id="HAP3137442.1"
                     /translation="MAIVDLSQLAAPDVVEELDYETILTERKVTLVSLYPEEQQDAVA
                     RTLTLESEPIVKLLQENAYREIIWRQRVNESARAVMLAYAAGHDLDNLGANYNVERLV
                     ITPADETTLPPTPAVMESDTDYRLRIQQAFEGMSVAGSTGAYQFHGRSADGRVADISV
                     ISPQPACVTVSVLSRENNGAASGELLAVVRNALNDEDVRPVADRVTVQSAVIVDYTID
                     AALYLYPGPESEPVLSAAKAKLQAYINAQHRLGRDIRKSAIYAALYVEGVQRVELVAP
                     VADIVLNETQASYCTAYSVNIGGNDE"
     gene            2063..2593
                     /locus_tag="IT892_004317"
     CDS             2063..2593
                     /locus_tag="IT892_004317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HAP3137443.1"
                     /translation="MSDTRLLPVGSSPLEVAAARACADIENTPVPLRRLWNPDNCPAN
                     LLPWLAWAFSVDRWDESWPEETKREVIRSTWFIHAHKGTIGAVRRVVEPLGYLINVTE
                     WWETNDPPGTFRLDIGVLETGITEEMYYEMERLIADAKPASRHLIGLNIIQDIPGYLF
                     TGALTWDGDIITVYPG"
     gene            2605..4290
                     /locus_tag="IT892_004318"
     CDS             2605..4290
                     /locus_tag="IT892_004318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP3137444.1"
                     /translation="MTVKYKTVITRAGAEKLAAATLPNGKKVNFAVMAVGDGGGKLPE
                     PDASQTKLVNEVWRHVLNKISQDKKHKNYVVAELVIPPETGGFWLREMGLYDDTGTLI
                     AVGNMAESYKPELAEGSGRAQTLRMVIMVSDIDTVELSIDTTLVMATQDYVDDKLAEH
                     EQSRRHPDATLKEKGFTQLSSATDSTSEALAATPKAVKAAYDLAKGKYSAQDATTAQK
                     GIVQLSSAIDSVSETLAATPKAVKAANDNADGRVPSSRKINGHSLNADTSVTSQDIFD
                     DQAIGLVTEDLDTLKTPGIYFQPANSNTSAARHYPENNAGTLVIYKNAGVTQVYRVYN
                     SSRSYSRSQYSTGAWTPWTPDDVFPVGAPVAWPSDSVPAGYAVMQGQTFDKAAYPLLA
                     VVYPSGVIPDMRGWTIKGKPASGRAILSQEQDGIKSHAHGASASSTDLGTKTTSAFDH
                     GTKTTTTFDYGTKTTNATGNHAHTFTVHRGDQAGGQAADGNEIATGTKTTSTAGNHAH
                     TVAIGAHNHNVGIGAHSHSVAIGAHGHTITIAASGNAENTIKNIAFNYIVRLA"
     gene            4290..4868
                     /locus_tag="IT892_004319"
     CDS             4290..4868
                     /locus_tag="IT892_004319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HAP3137445.1"
                     /translation="MTFKMTGESRTITVYNFRADTCEFIGKGDALIPAFTGLPACCTS
                     EKPPETRDGFIPVYDTENGCWAITEDHRGEVVYDTETGHEREITEPGQYPAGTTPVVP
                     ENPWQKWDGKTWVDDADAARNALTEAAKNNKNRLLKQANTAVATLQDSVDLEMATDDE
                     KTHLIAWKKYRVLLSRIQPEDAPDIEWPPLPV"
     gene            5004..>5991
                     /locus_tag="IT892_004320"
     CDS             5004..>5991
                     /locus_tag="IT892_004320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath protein"
                     /protein_id="HAP3137446.1"
                     /translation="MSDYHHGVQVIEINDGVRTISTVSTAIIGMVCTASDADEKTFLL
                     NEPVLITNVQSAIGKAGKQGSLSASLQAIADQCKPVIVAVRVAEGIEDPENPEAAHKQ
                     TISNIIGTTDENGKYTGLKALLTAKTVTGVKPRILGVPGLDSQEVATALASTCQSLRA
                     FGYVSAWGCKTISEAIDYRENFSQRELMVIFPDFLAWDTTANATATAWATARALGLRA
                     KIDQTVGWHKTLSNVGVNGVTGVSASVSWDLQEPATDANLLNQAGVTTLIRNDGFKFW
                     GNRTCSDDPLFLFENYTRTAQVLADTMAEAHAWAMDKPITPTLIRDIVSGINA"
BASE COUNT         1390 a         1642 c         1708 g         1251 t
ORIGIN      
        1 agatttattt catttctaag ttttgctatt tgataaatcc tttatgtggc tctcattaat
       61 ctaatgggat gaattatact gatattttaa agctgataat tgttgtttca tctcccataa
      121 aactccactt gattgccact agcctttcca gtcggcatcc tttccacatg aataatttaa
      181 attctttaca ggaaatcgct cgggcgatcc gcaaccttat ccgcaccggc attgtgaccg
      241 acgtcgaccc cgtcgagggg ctttgtcgtg tacagaccgg cgggatgcaa accacctggc
      301 ttaactggct gacctgccgc gccggccgct cgcgggtgtg gtgggctcct tctgttggcg
      361 agcaggtgct cattcttgcc attggtggcg agctggacac agcctttgtg ctgcccggca
      421 ttttctctga tgaccatcct gcgccgtcgg cctcgtccga tgcgtttcac gtcacttttc
      481 ctgacggggc ggttatcgag tacgaacccg aaaacggggc gctcaccgta tccggtatta
      541 aaaccgccga cgttaccgcg tcggagtcca ttaccgccat cgtgccggtg gtgctagtga
      601 aagccgaaac ccgcattacc ctcgatactc ccgaggtggt gtgtaccaac aagctcatca
      661 ccggcacgct cgaggtgaaa aaaggcggga cgatgtcggg gaacatcgag cacaccgaag
      721 ggaaatttac ctcaaacggc gtgcaggtcg atgcccacga tcatggtggc gtggagccgg
      781 gcggaaactg gacgaagggg gtcaaatgac ggtgcgttat ctgggaatga acagccagac
      841 cggcctcagt atttctgaag ttgagcacat caggcaaagc gtgcgcgaca ttctggtcac
      901 gccagtgggc tcgcgcgtca tgcgccgcga atatggctcg ctgttgtctg cactgattga
      961 ccagccgcag accccggcgc tgcgtctgca gattatggcc gcgtgctact ccgcgatcca
     1021 gaggtgggaa ccgcgcgtca gtttgtcgac catcaccgtt gaacgcggag aggatgacgg
     1081 cgcgatgtac gtcgatatga ccggcacgcg ttcggcatca ggccagcctt tttctatcac
     1141 ccttccactg agttaaacgt tatggctatt gttgacctga gccagctcgc cgcacctgat
     1201 gttgtggaag agttggatta tgaaaccatc ctgacagagc gaaaggtgac gctcgtctca
     1261 ctctatcccg aagagcaaca ggacgcggta gcgcgtacgc tgacgcttga atctgagccg
     1321 attgtgaagc tgttgcagga aaatgcttat cgggagatta tctggcgtca gcgggtgaat
     1381 gagtcggcac gggcggtgat gctggcttac gctgccggtc atgaccttga taacctcggc
     1441 gcaaattaca atgttgagcg tctcgttatt acgcctgctg atgagaccac gctgccgcca
     1501 acgcctgccg tcatggaatc ggacaccgat taccgtctgc gaattcaaca ggcttttgag
     1561 ggaatgagcg tggccgggtc gaccggtgcg tatcagtttc atggccgcag tgctgacggg
     1621 cgggtcgccg atatttctgt tatcagcccg cagcctgcct gcgtgaccgt gtcggtactg
     1681 tcccgggaga ataacggcgc ggcatccggg gaactgctcg ccgtggtgcg taatgctctc
     1741 aacgatgagg atgtgaggcc ggttgctgac cgcgtgaccg tgcagtcggc ggtcattgtc
     1801 gactacacca tcgatgccgc gctttatctt tatcccggcc ccgaaagcga gccggtgctc
     1861 agtgcggcaa aagcgaagct gcaggcttat atcaacgcgc agcaccggct cgggcgcgat
     1921 atccgcaagt ctgccatcta tgccgcgctt tacgtcgagg gggtgcagcg tgtcgaactt
     1981 gtcgcgccgg tcgctgacat cgtactcaat gagacacagg cgtcatattg cactgcttac
     2041 agcgtaaaca tcgggggcaa cgatgagtga tacccgtctg ctgccggtgg gctcgtcgcc
     2101 gcttgaggtg gcggcggcgc gcgcctgcgc ggatatcgaa aatacgcccg tcccgctgcg
     2161 tcgtctatgg aaccctgaca actgccccgc gaatctgctg ccgtggctgg cctgggcgtt
     2221 ttcggttgat cgctgggatg agagctggcc ggaagaaacc aaacgcgagg ttatccgcag
     2281 cacgtggttt atccatgcgc ataaagggac gataggtgcg gtgcgtcgtg tggtcgagcc
     2341 gctcgggtat ctgattaacg tgacggagtg gtgggagacg aacgaccccc cgggcacgtt
     2401 tcgccttgat atcggcgtgc tggagaccgg tatcaccgag gaaatgtatt acgaaatgga
     2461 aaggctgatt gccgatgcaa agccagccag ccgccatctt attggcctga atattatcca
     2521 ggacataccg ggttatctct tcaccggagc cctgacctgg gacggcgaca tcatcacggt
     2581 ttaccccgga taagtgagaa cacaatgaca gtgaaatata aaaccgttat cacccgagcc
     2641 ggtgcggaaa aactggcggc ggcgacgctc ccgaacggga agaaagtcaa ttttgctgtg
     2701 atggccgtcg gggacggcgg cggaaaactg cccgaaccgg acgccagcca gacaaaactc
     2761 gtcaatgagg tctggcgtca tgtcctgaac aaaatcagcc aggacaaaaa acataaaaat
     2821 tatgtcgtgg cggagctggt gatccccccg gagaccggcg gtttctggct gcgtgaaatg
     2881 gggctttacg atgacaccgg cacgctgatt gcggtcggca atatggccga aagctacaaa
     2941 cccgagctgg cggaaggatc aggtcgtgcg cagacgctgc gtatggtgat catggtgagt
     3001 gatatcgaca cggtcgagtt gtccatcgat accacgctgg tgatggcgac gcaggattat
     3061 gtcgacgaca aactcgcaga gcatgagcag tcccgccgcc atcctgacgc cacgctgaaa
     3121 gaaaaagggt tcacgcagtt aagcagtgcg accgacagca cgtctgaggc gctcgccgcg
     3181 acaccgaaag cggttaaggc ggcgtatgac cttgcgaaag gtaaatactc ggctcaggat
     3241 gcgaccacgg cgcagaaagg gattgttcag ctcagtagcg ccatcgacag cgtgtctgag
     3301 acgctcgccg caacgccaaa agcggtgaaa gcggcgaatg ataatgctga tggccgcgtt
     3361 ccttcctcgc gcaaaattaa cggacactcc ctgaatgctg acaccagtgt tacctcgcag
     3421 gatattttcg acgaccaggc tattgggctg gtaacggagg atttagacac ccttaaaacg
     3481 ccgggtattt actttcagcc agcgaattct aatacctcag ccgccagaca ttaccctgaa
     3541 aataacgccg ggacgctggt catttataaa aatgccggag tgactcaggt ataccgggtt
     3601 tataacagct cccggagcta ctcgcgcagt cagtattcaa caggcgcatg gacaccgtgg
     3661 acgcctgatg atgtttttcc ggtaggcgct cccgttgcgt ggccgtctga cagtgttcct
     3721 gctggctatg ccgtcatgca gggacaaact tttgataaag ccgcgtatcc gctgcttgct
     3781 gtggtgtacc catcgggtgt tattcctgat atgcggggct ggacaatcaa aggtaaaccc
     3841 gcaagtgggc gcgctatttt gtctcaggag caggacggca ttaaatcgca cgcccacggt
     3901 gccagcgcat cgagcaccga tttagggacg aaaaccacca gtgcttttga ccacggaacg
     3961 aaaaccacca cgacctttga ctacgggaca aaaaccacta atgcaaccgg caaccatgcg
     4021 cacactttta ccgtacaccg gggagatcag gccgggggac aggccgccga cggtaacgaa
     4081 atagcgacgg gaacgaaaac aacatcaact gcaggtaatc acgcgcatac cgtggcgatt
     4141 ggtgcccaca atcataatgt cgggattggc gcacactcgc actccgttgc tattggcgca
     4201 cacggtcaca ccattacgat cgccgcgtcg ggtaatgcag aaaacaccat caaaaacatc
     4261 gcatttaact atatcgtgag actcgcataa tgacgtttaa aatgaccgga gaaagccgga
     4321 ctatcactgt gtataacttt cgtgcagaca cctgtgaatt tattggaaaa ggtgacgccc
     4381 tgataccggc atttaccgga ttgcccgcct gctgcaccag tgaaaagccc ccggaaaccc
     4441 gagacggatt tattccggtt tatgacactg aaaatggttg ctgggctatc actgaagacc
     4501 accggggtga ggttgtctat gacaccgaaa caggtcatga gagggagata accgagccgg
     4561 gtcagtatcc ggcaggaaca acaccggttg tgccggaaaa cccgtggcag aaatgggatg
     4621 gtaaaacatg ggttgatgat gctgatgctg cacgtaatgc attgacagag gctgcgaaaa
     4681 acaacaaaaa caggcttctt aaacaggcca atactgcggt tgcgacatta caggactccg
     4741 ttgatctgga gatggcaacc gacgatgaaa aaacgcacct cattgcatgg aaaaaatacc
     4801 gtgttttact gagccgcatc cagccggagg atgctccgga tattgaatgg ccgccgctgc
     4861 cagtctgatc cgacatctgg cgggcagttg cccgcctttt cctttcccgt cgttgtgtca
     4921 gaccttagcc aaccctgaca aatagcccgc acccgccaca caacagaaaa tatcactcac
     4981 cccttaacca cggagttaaa cggatgagtg actatcatca cggcgtgcag gtcatcgaga
     5041 ttaacgatgg cgtgcgcacc atttccaccg tttcgacggc catcatcggc atggtctgca
     5101 cggccagcga tgctgacgaa aaaacatttc tcctcaatga gccggtgctc attacgaacg
     5161 tgcagagcgc tatcggtaag gccggtaaac agggctcgct gtcggcgtcc ctgcaggcta
     5221 tcgctgacca gtgcaagccg gtcatcgtgg ccgtgcgtgt ggccgaaggt attgaagatc
     5281 cggagaaccc cgaggcggcg cacaaacaga ccatttctaa tatcatcggc accaccgacg
     5341 aaaacggcaa atataccggg ctgaaagccc tgctgacggc gaaaaccgtc accggcgtta
     5401 agccacggat tctcggcgtg ccggggctgg attcacagga ggtggcgacc gcactcgcgt
     5461 ccacctgtca gagcctgcgc gcctttggct atgtcagcgc atggggctgt aaaaccattt
     5521 ccgaggccat cgactaccgc gagaatttca gccagcgtga gctgatggtc atcttccctg
     5581 attttctggc atgggacacc acggcgaacg cgactgcgac agcctgggcg acggcgcgcg
     5641 cgctcggcct gcgtgccaaa atcgaccaga cggtcggctg gcataaaacc ctgtctaacg
     5701 ttggcgttaa cggtgtgacc ggcgtcagtg cctcagtatc gtgggatttg caggaaccgg
     5761 cgaccgacgc caacctgctg aatcaggccg gtgtcaccac gcttatccgc aatgatggtt
     5821 tcaagttttg gggaaaccgt acctgctcgg atgatccgct tttcctgttt gagaactaca
     5881 cccgcaccgc gcaggtactg gccgacacga tggcggaggc gcacgcgtgg gcgatggata
     5941 aacccattac cccgaccctc attcgcgaca tcgtttccgg tatcaatgcc a
//
LOCUS       DACAOP010000171         5960 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.172, whole genome shotgun sequence.
ACCESSION   DACAOP010000171 DACAOP010000000
VERSION     DACAOP010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5960
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.172"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            136..1287
                     /gene="yiaY"
                     /locus_tag="IT892_004321"
     CDS             136..1287
                     /gene="yiaY"
                     /locus_tag="IT892_004321"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine dehydrogenase"
                     /protein_id="HAP3137447.1"
                     /translation="MAASTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDNMLTK
                     LGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAGLKLLKENNCDSVISLGGGSPHD
                     CAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
                     MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALK
                     AVTMIAENLPLAVEDGSNAKAREAMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYNLP
                     HGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGAEACINAIRELAKKV
                     DIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM"
     gene            1452..2990
                     /locus_tag="IT892_004322"
     CDS             1452..2990
                     /locus_tag="IT892_004322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HAP3137448.1"
                     /translation="MTNNPPSAQIKPGEYGFPLKLKARYDNFIGGEWVAPADGEYYQN
                     LTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAHTSVQDRAAILFKIADRMEQNLE
                     LLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
                     LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGV
                     VNVVNGAGGVIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNI
                     FFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESI
                     RSGNPLDSVTQMGAQVSHGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLE
                     PTILFGQNNMRVFQEEIFGPVLAVTTFKTMEEALELANDTQYGLGAGVWSRNGNLAYK
                     MGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKCLLVSYSDKP
                     LGLF"
     gene            complement(3209..3352)
                     /locus_tag="IT892_004323"
     CDS             complement(3209..3352)
                     /locus_tag="IT892_004323"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137449.1"
                     /translation="MNNSSKTSTVQIKRIKPSIIYRLLLIGLGSPMVIYGLVRPLTIE
                     TRD"
     gene            3535..3858
                     /locus_tag="IT892_004324"
     CDS             3535..3858
                     /locus_tag="IT892_004324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HAP3137450.1"
                     /translation="MFLDYFALGVLIFVFLVIFYGIIILHDIPYLIAKKRNHPHADAI
                     HVAGWVSLFTLHVIWPFLWIWATLYRPERGWGMQSHDSSVMQLQQRIAGLEKQLADIK
                     SSSAE"
     gene            3864..5000
                     /locus_tag="IT892_004325"
     CDS             3864..5000
                     /locus_tag="IT892_004325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAP3137451.1"
                     /translation="MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLI
                     LLMNYNHPYTFKAQKAVISIPVVPQVTGVVIEVTDKKNTLIKKGEVLFRLDPTRYQAR
                     VDRLMADIVTAEHKQRALGAELDEMAANTQQAKATRDKFAKEYQRYARGSQAKVNPFS
                     ERDIDVARQNYLAQEASVKSSAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLE
                     QTIVRAPSDGYVTQVLIRPGTYAASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGD
                     DAEVVFNALPGKVFSGKLAAISPAVPGGAYQSTGTLQTLNTAPGSDGVIATIELDEHT
                     DLSALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWVHYLYLDH"
     gene            complement(4997..>5960)
                     /locus_tag="IT892_004326"
     CDS             complement(4997..>5960)
                     /locus_tag="IT892_004326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP3137452.1"
                     /translation="QLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADFESKV
                     GLKVFDRTTRQLMLTPFGTALLPYINDMLDRNEQLNNFIADYKHEKRGRVTIYAPTGI
                     ITYLSKHVIDKIKDIGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDESLVA
                     SFITQYAVTAYASQRYLEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGSKEVR
                     DYRVKGNYVCDNTQSALELARNHLGIVFAPDKSVQSDLQDGTLVPCFQQPYEWWLDLV
                     AIFRKREYQPWRVQYVLDEMLREIRHQLAQSQQLRPEQAAESED"
BASE COUNT         1481 a         1409 c         1552 g         1518 t
ORIGIN      
        1 aaaaaagcac attgtttaat gaatacaatg tgctttttat tagattaatt ttgataatca
       61 ataatactga tcatattttc gaatgacaat cctcagtaag ctgcccgccc ttttttacac
      121 tttcaggagt gtgttatggc agcttcaacg ttctttattc cttctgtgaa tgtcatcggc
      181 gctgattcat tgactgatgc aatgaatatg atggcagatt atggatttac ccgtacctta
      241 attgtcactg acaatatgtt aacgaaatta ggtatggcgg gcgatgtgca aaaagcactg
      301 gaagaacgca atatttttag cgttatttat gatggcaccc aacctaaccc caccacggaa
      361 aacgtcgccg caggtttgaa attacttaaa gagaataatt gcgatagcgt gatctcctta
      421 ggcggtggtt ctccacacga ctgcgcaaaa ggtattgcgc tggtggcagc caatggcggc
      481 gatattcgcg attacgaagg cgttgaccgc tctgcaaaac cgcagctgcc gatgatcgcc
      541 atcaatacca cggcgggtac ggcctctgaa atgacccgtt tctgcatcat cactgacgaa
      601 gcgcgtcata tcaaaatggc gattgttgat aaacatgtca ctccgctgct ttctgtcaat
      661 gactcctctc tgatgattgg tatgccgaag tcactgaccg ccgcaacggg tatggatgcc
      721 ttaacgcacg ctatcgaagc atatgtttct attgccgcca cgccgatcac tgacgcttgt
      781 gcactgaaag ccgtgaccat gattgccgaa aacctgccgt tagccgttga agatggcagt
      841 aatgcgaaag cgcgtgaagc aatggcttat gcccagttcc tcgccggtat ggcgttcaat
      901 aatgcttctc tgggttatgt tcatgcgatg gcgcaccagc tgggcggttt ctacaacctg
      961 ccacacggtg tatgtaacgc cgttttgctg ccgcacgttc aggtattcaa cagcaaagtc
     1021 gccgctgcac gtctgcgtga ctgtgccgct gcaatgggcg tgaacgtgac aggtaaaaac
     1081 gacgcggaag gtgctgaagc ctgcattaac gccatccgtg aactggcgaa gaaagtggat
     1141 atcccggcag gcctacgcga cctgaacgtg aaagaagaag atttcgcggt attggcgact
     1201 aatgccctga aagatgcctg tggctttact aacccgatcc aggcaactca cgaagaaatt
     1261 gtggcgattt atcgcgcagc gatgtaatca tcatttccac aacggctggc aaattgtcag
     1321 ccgctttttc aactatctct gtaacccttg cccgtaaatt cgtgatagct gtcgtaaagc
     1381 tgttaccgac tggcgaagat ttcgccagtc acgtctaccc ttgttatacc tcacaccgca
     1441 aggagacgat catgaccaat aatccccctt cagcacagat taagcccggc gagtatggtt
     1501 tccccctcaa gttaaaagcc cgctatgaca actttattgg cggcgaatgg gtagcccctg
     1561 ccgacggcga gtattaccag aatctgacgc cggtgaccgg gcagctgctg tgcgaagtgg
     1621 cgtcttcggg caaacgagac atcgatctgg cgctggatgc tgcgcacaaa gtgaaagata
     1681 aatgggcgca cacctcggtg caggatcgtg cggcgattct gtttaagatt gccgatcgaa
     1741 tggaacaaaa cctcgagctg ttagcgacag ctgaaacctg ggataacggc aaacccattc
     1801 gcgaaaccag tgctgcggat gtaccgctgg cgattgacca tttccgctat ttcgcctcgt
     1861 gtattcgggc gcaggaaggt gggatcagtg aagttgatag cgaaaccgtg gcctatcatt
     1921 tccatgaacc gttaggcgtg gtggggcaga ttatcccgtg gaacttcccg ctgctgatgg
     1981 cgagctggaa aatggctccc gcgctggcgg cgggcaactg tgtggtgctg aaacccgcac
     2041 gtcttacccc gctttctgta ctgctgctaa tggaaattgt cggtgattta ctgccgccgg
     2101 gcgtggtgaa cgtggtcaat ggcgcaggtg gggtaattgg cgaatatctg gcgacctcga
     2161 aacgcatcgc caaagtggcg tttaccggct caacggaagt gggccaacaa attatgcaat
     2221 acgcaacgca aaacattatt ccggtgacgc tggagttggg cggtaagtcg ccaaatatct
     2281 tctttgctga tgtgatggat gaagaagatg cctttttcga taaagcgctg gaaggctttg
     2341 cactgtttgc ctttaaccag ggcgaagttt gcacctgtcc gagtcgtgct ttagtgcagg
     2401 aatctatcta cgaacgcttt atggaacgcg ccatccgccg tgtcgaaagc attcgtagcg
     2461 gtaacccgct cgacagcgtg acgcaaatgg gcgcgcaggt ttctcacggg caactggaaa
     2521 ccatcctcaa ctacattgat atcggtaaaa aagagggcgc tgacgtgctc acaggcgggc
     2581 ggcgcaagct gctggaaggt gaactgaaag acggctacta cctcgaaccg acgattctgt
     2641 ttggtcagaa caatatgcgg gtgttccagg aggagatttt tggcccggtg ctggcggtga
     2701 ccaccttcaa aacgatggaa gaagcgctgg agctggcgaa cgatacgcaa tatggcctgg
     2761 gcgcgggcgt ctggagccgc aacggtaatc tggcctataa gatggggcgc ggcatacagg
     2821 ctgggcgcgt gtggaccaac tgttatcacg cttacccggc acatgcggcg tttggtggct
     2881 acaaacaatc aggtatcggt cgcgaaaccc acaagatgat gctggagcat taccagcaaa
     2941 ccaagtgcct gctggtgagc tactcggata aaccgttggg gctgttctga tataagaagc
     3001 tggtcgcatt gggtattcat tgcctgatgc gacgcttacg cgtcttatca tgcctacggg
     3061 aacctgaccg taggccggat aaggcgtaca cgccgcatcc ggcataaaca aagcgcacgt
     3121 tgttacaatt tacgttttaa acctacgtgc gcaataaccc agactacgcc aacagaagta
     3181 cgtttctggg gcgtgttttg tcaggagttt aatctcgcgt ttcgatggtg agcgggcgaa
     3241 ccaggccgta aatcaccatt ggtgatccga ggccaatcag caataaacgg tagataattg
     3301 aaggtttaat acgcttaatc tgtactgtgg atgttttact ggagttattc attagtttgg
     3361 ccaatagttc cactatttca atatgataaa cctcgtcctg ttgaaaaacc agacagcaca
     3421 tttaagaaag tatataaaaa acaatatgtc gttatataaa taaggaaatt gcactgcatc
     3481 atggcatttc ataatatgcg ttaattgttc ttttttatat tctttgaggg aaatatgttc
     3541 ctggactatt ttgcactggg agtgcttatt tttgtatttc tggtgatctt ctatgggatc
     3601 attattttac atgatattcc ctacctgatt gccaaaaaac gtaatcatcc tcatgccgac
     3661 gccattcatg ttgctggttg ggtgagtctt tttacgttac atgttatctg gccgtttttg
     3721 tggatttggg ccacgcttta ccgcccggag cggggatggg gaatgcaaag ccatgattca
     3781 tccgttatgc aactgcaaca gcgcattgcc gggctggaga aacagctcgc cgacatcaaa
     3841 tcctcttctg ccgagtaata cttatggatt tactgattat tttgacctat gtggcttttg
     3901 catgggcaat gtttaagatc ttcaaaattc ccgtaaataa atggaccatt cccacagcgg
     3961 ccctgggtgg aatatttatt gtcagcggtc taattctgtt aatgaactat aaccatccgt
     4021 atacctttaa agcgcaaaaa gcggttattt ctattcctgt tgtcccacag gtgactggtg
     4081 tggtgattga agtgacggat aagaaaaata cgctgattaa aaaaggtgag gtgctatttc
     4141 gactggaccc gacgcgttat caggcgcggg tggatcggct gatggcggat atcgttaccg
     4201 cagaacataa acagcgggcg ttgggcgcag agttagatga gatggcggcg aatactcagc
     4261 aggcaaaggc cacgcgggat aaattcgcta aagagtatca gcgttacgca cgtggcagcc
     4321 aggcgaaagt aaacccgttt tcagaacgcg atatcgatgt ggcgcggcaa aattatctgg
     4381 cgcaggaagc ctccgtgaag tcatcggcgg cggaacaaaa acagatccag agccagctgg
     4441 atagcctggt gttgggtgaa cattctcaaa tcgccagcct gaaagcacag ctcgcggaag
     4501 caaaatataa ccttgagcag acgatagtgc gtgcgccgag cgatggttat gtgacccagg
     4561 tactgattcg tccgggtacc tatgccgcgt cgctgccgct acgtccggtg atggtgttta
     4621 tacccgatca gaaacgacaa atcgtggcgc agttccgtca gaactccttg ctgcgactgg
     4681 ctcctggcga cgatgcggaa gtggtgttta atgctctgcc aggtaaggta ttcagcggta
     4741 agctggcagc cattagtcca gccgttcccg gcggagctta tcagtcgacc ggcaccttac
     4801 agacgttaaa cacagcgccg ggttcagatg gcgttatcgc gaccattgaa ctggatgagc
     4861 acactgattt gagcgcttta ccagacggta tttacgccca ggtggcggtt tactctgatc
     4921 atttcagcca tgtctcggtg atgcgcaaag tgctattacg catgaccagc tgggtgcatt
     4981 acctttatct cgatcattaa tcttcgcttt ccgccgcttg ttcaggccgc agttgctgcg
     5041 actgagcaag ctggtggcga atttcacgca gcatttcatc cagcacatac tggacccgcc
     5101 agggctggta ttcccgttta cggaagatag ccaccagatc cagccaccat tcatagggtt
     5161 gctgaaagca gggcaccagc gtgccgtctt gcaggtcgct ctgcacactt ttgtctggcg
     5221 caaacacaat ccccaggtga tttcgtgcca gctccagcgc agattgcgtg ttgtcgcaaa
     5281 cgtaatttcc cttcacgcga taatcccgca cctctttact cccggcgacg ttgaagcgcc
     5341 agatattcgc gtcgtcgatc atcatcgagt cgatcaaaat acaggagtga tgttcgagtt
     5401 cgtcaggacg gctaatggga tgtttctcaa gatagcgctg gctggcataa gcggttacgg
     5461 catattgggt aataaaactg gcaaccagcg attcatcttt tggtggagcg tagctgatta
     5521 aaacatcaca atcatcagga aattcgacgc cttcataaaa ggcattacgc tcaagattgc
     5581 aggtttttag cgataaggtg atatcaccga tatctttaat tttatcgatt acatgtttgg
     5641 ataaataggt aattatgccg gttggggcgt agatggtgac ccgaccacgt ttctcatgct
     5701 tataatctgc aataaaatta ttaagttgct cgtttctgtc cagcatgtcg ttgatgtacg
     5761 gtaacagcgc ggtgccaaaa ggtgtgagca tcagctgccg ggtggttcgg tcaaagactt
     5821 ttaaacccac ttttgattca aaatcagcaa gatatttgct gacgttggcc tgtgcgatgc
     5881 caagtacagt cgcggcatgg ctgatatttt cactggcagc gattaccgag ataattttta
     5941 actcccggta cttaagttgt
//
LOCUS       DACAOP010000172         5885 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.173, whole genome shotgun sequence.
ACCESSION   DACAOP010000172 DACAOP010000000
VERSION     DACAOP010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5885
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.173"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..1042
                     /gene="asmA"
                     /locus_tag="IT892_004327"
     CDS             <1..1042
                     /gene="asmA"
                     /locus_tag="IT892_004327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HAP3137453.1"
                     /translation="AQVTLTEKPEWQLRLQFPQLNLDNLIPLNETANGENGAAQQGLS
                     QSTLPRPVISSRIDEPAYQGLQGFTADILLQASNVRWRGMNFTDVATQMTNKSGLLEI
                     TQLQGKLNGGQVSLPGTLDATSINPRINFQPRLENVEIGTILKAFNYPISLTGKMSLA
                     GDFSGADIDADAFRHNWQGQAHVEMTDTRMEGMNFQQMIQQAVERNGGDVKAAENFDN
                     VTRLDRFTTDLTLKDGVVTLNDMQGQSPMLALSGAGTLNLAEQTCDTQFDIRVVGGWN
                     GESKLIDFLKETPVPLRVYGNWQQLNYSLQVDQLLRKHLQDEAKRRLNDWAERNKDSR
                     NGKDVKKLLEKM"
     gene            complement(1494..3077)
                     /locus_tag="IT892_004328"
     CDS             complement(1494..3077)
                     /locus_tag="IT892_004328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HAP3137454.1"
                     /translation="MEWIADPSIWVGLVTLVIIELVLGIDNLVFIAILAEKLPPAQRD
                     RARITGLMLAMVMRLLLLASISWLVTLTQPLFSFRSFTFSARDLIMLFGGFFLLFKAT
                     MELNERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVITAIGMVDHLLVMMAA
                     VVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAI
                     GFSVMIEAFNQLAIFNRRRFLSANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLVD
                     HGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEDEIRQLLERNQHT
                     RLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLIRQPLVFPETLPLLPALEQFR
                     NARTHFAFVVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANG
                     HMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPKPGEEVQVGDYLLKTLQVESHR
                     VQKVQIIPLRKDGEMEYEV"
     gene            3854..4744
                     /gene="galF"
                     /locus_tag="IT892_004329"
     CDS             3854..4744
                     /gene="galF"
                     /locus_tag="IT892_004329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GalU regulator GalF"
                     /protein_id="HAP3137455.1"
                     /translation="MANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVTIMNV
                     RQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMVARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLS
                     ADIWAELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTY
                     GMRNLKEGTKFRESIKKLLA"
     gene            5138..5767
                     /locus_tag="IT892_004330"
     CDS             5138..5767
                     /locus_tag="IT892_004330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP3137456.1"
                     /translation="MNWQLISFFGDSTVLLPSAAALFIVLMLRKTSRLLAWQWSLLFG
                     ITGAIVCASKLAFMGWGLGFRELDYTGFSGHSALSAAFWPIFLWLLSARFSAGLQKAA
                     VATGYILAAVVGYSRLAIHVHSVSEVIAGLLLGAAGSALFLMLQKRTTHSESVSISWG
                     GVVCLVMVPLILLHSGNKAPTQSLLGQIATALGPLDKPFTRTDLHKQAW"
BASE COUNT         1442 a         1520 c         1581 g         1342 t
ORIGIN      
        1 agcacaggtc acgttgacag agaaaccgga atggcagctg agactgcaat tcccgcaact
       61 gaatcttgac aacctcatcc cccttaatga aacagcgaat ggtgagaacg gtgccgcgca
      121 gcaagggctg agccaatcaa cgttgccgcg cccggtcatt tcttcgcgta ttgatgaacc
      181 ggcctatcag ggactgcaag gctttacggc tgatattttg ttgcaggcca gtaacgtgcg
      241 ctggcgcgga atgaatttta cagatgttgc cacgcaaatg accaacaagt cgggtttgct
      301 ggaaattact caactgcagg gcaaacttaa cggtggacag gtttcactgc cgggcacgtt
      361 ggacgcgaca tcaataaatc cgcggataaa cttccagcca cggctggaaa acgttgagat
      421 tggcaccatt ctgaaggcgt ttaactatcc gatttcgttg accggaaaga tgtcactggc
      481 tggtgatttc tccggtgctg acatagatgc cgacgcattc cgccacaact ggcaaggaca
      541 ggcacatgtc gaaatgaccg acacacgcat ggaagggatg aacttccagc agatgattca
      601 gcaagcggta gaacgtaatg gtggtgatgt gaaggccgct gaaaacttcg ataacgtgac
      661 gcgtcttgac cgctttacca ccgatttgac gttgaaggat ggcgtcgtga cgttaaacga
      721 catgcaaggt caatcgccca tgctggcgct ttccggggct ggtacgttga atctggcgga
      781 gcaaacctgc gacacccagt ttgatattcg ggtcgtgggt ggctggaacg gagaaagcaa
      841 actgattgat ttcctcaaag aaacgccagt accgctgcgg gtttatggca actggcagca
      901 acttaattac agcctgcaag tggatcagtt actgcgtaaa catctacagg atgaagcaaa
      961 acgccgtctt aacgactggg ccgagcggaa taaagattcc cgcaatggca aagatgtgaa
     1021 gaagttgctg gagaagatgt aggttaccag gtgacctgtc ctgtaggcct gataagacgc
     1081 gtaaagcgtc gcatcaggcg ttcgtggcgg caccattata ttctgaatat gtaagatcga
     1141 aggctgttcc gttcacttga tgttcctcgc tactatggaa cgctcaagcc ggtgaacgtg
     1201 ccagggtggc tcaatcgcca ccaccctggc aacccgggct cccggcggta aatcgccgct
     1261 ggcgtggttc cctcatctta ttcctttcgg ctatcgggta cgggcgcgag gtaacatcac
     1321 tgtaaaacgc gccctcagcc cacatccatg tgggctgccc cggcctacag gaaacgattc
     1381 ggcgatttac agccggaccc acacccccgc tgtgatgtcc atgtaccaca gacaacgctt
     1441 cattgctgaa gttataaggc gttacgcagc attgggtaaa atggccgata ccatcacacc
     1501 tcgtactcca tctcgccatc cttacgcagc ggaataatct gcaccttctg cacgcgatgg
     1561 ctttctacct gcaacgtttt aagcaaataa tcccccacct gaacttcttc gccaggtttt
     1621 ggaatacgct gcaaatattc catcaatagc ccggcaatgg tgtgatattc acgtttttca
     1681 tccagcggca gcggcacata ttgcaccaga tcttccagcg gcatatgacc attcgccgtc
     1741 caggaaccgt ccgcattctt ctgaatatca tggcgggcgt cgatctcttc cacttcgttc
     1801 ggtaagttac cggcaatggt ttcagtgacg tcacttaatg tcacaatacc ttccaccgag
     1861 ccaaactcat ccaccacaaa agcaaagtgt gtgcgggcat tacggaactg ctccagggca
     1921 ggtaacaacg gcaaggtttc cgggaacacc agcggctgac gaatcaacac ccgcaggttg
     1981 agcggttcgc cgcgcagtga ctgttgtaac aggtcgataa cgtgaacaac accgagcaaa
     2041 tcttctgcgt catcgccatc agtaacgaca agccgcgtat gctgatttcg ctccagcagc
     2101 tggcggatct cgtcttccgg cgcgttgaga tcgatatgct caatatcgtg gcgcgacgtc
     2161 ataatgctgc tgacggtacg ctggttaaga ttaagtaccc gctcaatcat ccgccgttcc
     2221 tgcggattaa agatctgctg gttaccatga tccaccagca tggacgcggt ttcggcgtcc
     2281 agttccgcat cttctttttg cccgctaagc aggcgcatta ccgcttcggt agtccgctgg
     2341 cgcagtgtct ggttagcgga aagaaaacgt cgccggttaa agatagccaa ctgattgaac
     2401 gcctcgatca tcaccgagaa accaatggca gcgtacaggt agcctttcgg aatgacgaag
     2461 ccgaaacctt ccgccaccag gctaaagcca atcatcaaca ggaagcttaa gcagagaata
     2521 acgatcgtcg gatgactgtt aacgaactgg gttaacggct tgctggccat caacatcagg
     2581 ctgatagcga taaccacggc ggccatcatg accagtaaat ggtcgaccat cccgatggcg
     2641 gtaatcaccg agtcgagtga gaagatagcg tccagcacca ctatttgtgt caccacgccc
     2701 cagaacttcg cacctttgcg ttgcgtgggg ttattgctat ctttcccttc cagccgttcg
     2761 ttcagctcca tcgtggcttt gaacaacagg aagaaaccac caaacagcat gattaagtcg
     2821 cgggcgctaa aggtaaacga gcggaagctg aacagcggtt gagtaagggt gaccagccag
     2881 gagatagagg ccagcagcag gagacgcatc accatcgcca gcatcaggcc agtgatccgc
     2941 gctcggtcgc gctgggcggg agggagcttc tcggcgagga tagcgataaa gaccaggtta
     3001 tcgataccca acaccagttc gataatcacc agcgtgacga gacctaccca gattgacgga
     3061 tcggcaatcc attccatatg tattaaaacc tgtacgactg cggtatgtgt taccacgatc
     3121 atggataaga tgagtctaaa atgcaataac gacgcggata tcactccgcc aggggtggat
     3181 atatttccag caaattaaga gaacagaaaa gaattatgtt ccagaaaaga tcagcggaaa
     3241 aataacaata tggcggaacg cgctggaata agcttgctga tatcagaacc ataacccgct
     3301 gcgttttgcc cggcgcaaaa gcgagggcgg tcccgtcgtt cgccacggta ggcacccttc
     3361 ctcatccccg ggtgaaatgc gaagcccgct cacaaaatcg gcataattca catcatgaag
     3421 tgagcgcaga atagtgccga tcgccgttct ctgccgtggt ttacggttat tatcctgcca
     3481 tatctggctg tttgtgctga aatagattgc ctggcgaaat taattatcta tatctattct
     3541 ttccgcacac atgggcaccg cagtctgcag ctggcagggt ctgcgtacca aaggccgcgg
     3601 tgtaggggcc ttgcggcgac atcgcgctgt gcagggaagc gggccgctga atatcctgat
     3661 ggagaataag attattctca cttcaaactg ttggtaaaag gaagttgtgt gtattctttt
     3721 aggtgacagt gaatttaaga atttggcggg cagatgcccg ggcagtatcc gtgtattatc
     3781 agttccaatg gatttgtgac atgtaaaatt ttgcaaaact gcgtgttttg caaccaaaca
     3841 ggtgaagatg aatatggcga atttgaaagc ggttattccg gtcgcaggac taggcatgca
     3901 tatgctgccg gccacaaagg caattcccaa ggagatgctg ccgatcgttg ataagccaat
     3961 gattcagtac attgttgacg aaatcgtcgc cgccgggatc aaagagattg tcctggtgac
     4021 gcactcctcg aagaatgcag tggaaaacca ctttgatacc tcctacgagc tggaagccct
     4081 gcttgagcag cgcgtgaagc gccagctgct ggcggaagtc caggccattt gcccgccggg
     4141 cgtaaccatc atgaacgtgc gtcaggcaca gccgctgggt ctgggccact ccatcctctg
     4201 cgcccgcccg gtagtcgggg acaacccgtt tgtggtggtg ctgccggata tcattctcga
     4261 tggcggcact gcggacccgc tgcgctataa cctcgctgcc atggtcgccc gttttaacga
     4321 gaccggccgc agccaggtgc tggcgaaacg catgccgggc gatctctccg aatactccgt
     4381 tatccagacc aaagagccaa tggtggccga agggcaggtg gcgcgtatcg tcgagtttat
     4441 tgaaaaaccg gacgaaccgc agaccctgga ctccgacctg atggcggtgg gccgctacgt
     4501 gctgtcggca gatatctggg ctgaacttga acgaacccag ccgggcgcct ggggccgtat
     4561 ccagctaacc gacgccattg ccgaactggc gaagaagcag tccgttgacg cgatgctgat
     4621 gaccggcgaa agctatgact gcggtaaaaa aatgggctac atgcaggcct tcgtcaccta
     4681 cgggatgcgt aacctgaaag aaggtaccaa attccgcgaa agcattaaaa aactgctggc
     4741 ctgagcgccg gcgtaagggt gagcggcagg gcaggggtat tttgccacgc cgctcataac
     4801 gttatgcaga aattattcat aacgtgaatg ttataacgat tgtaaagaaa cgtatggctt
     4861 cggagacttc tggtagtttg tctctggcct ctgtggtgca atggtcggag tagcggcaat
     4921 aatgctttgt gaatagtcac ttagtgcgac aattcttaaa gcgcagggaa agcggtcaac
     4981 gtcagccaaa aataaaactt gactgcgatc atgtttccgc tttaaacatc tcacttgcat
     5041 gcataaaaat gtgaaatgaa ttggcatgcg agctggtaca gacattacgg ataatccctg
     5101 agcacggcag tggacatcat cgaaggatca caggtatatg aactggcaac tcatctcatt
     5161 ttttggcgat agcaccgttt tgctgcccag cgcagcggcg ctgtttattg tcctgatgct
     5221 gcgtaaaacg tcgcggttgc tggcgtggca gtggagtttg ctgttcggca tcaccggcgc
     5281 catcgtctgc gcctccaaac tggcctttat gggctggggt ctgggttttc gcgagctgga
     5341 ttacaccggc ttcagcggcc actcagcgct ctccgcggcc ttctggccta tcttcctgtg
     5401 gctgcttagc gcgcgttttt ccgcgggctt gcaaaaagca gccgtcgcca ccggctatat
     5461 tctggccgct gtggtggggt attcacggct ggccatccat gtgcattctg tctcggaagt
     5521 gatcgctggc ctgctgctcg gcgctgctgg cagcgctttg ttcctgatgc tgcaaaaacg
     5581 taccacccat tcggaaagcg tgagtatttc ctggggcggc gtcgtgtgcc ttgtgatggt
     5641 cccgcttatc ctgttgcata gcggcaataa agcgccgact cagtccctgc tggggcaaat
     5701 cgccaccgcg ttgggaccac tggataaacc ctttacgcgt accgatctgc ataagcaagc
     5761 ctggtaatcg ccatttgttt tacaggggaa attaagtttt cgccgattaa ttagacaaat
     5821 aagaaaataa tggtgatgct gccaatttac tgatttagtg tatgatggtg attttaaggt
     5881 gcttg
//
LOCUS       DACAOP010000173         5716 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.174, whole genome shotgun sequence.
ACCESSION   DACAOP010000173 DACAOP010000000
VERSION     DACAOP010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5716
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.174"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            31..795
                     /locus_tag="IT892_004331"
     CDS             31..795
                     /locus_tag="IT892_004331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1120 domain-containing protein"
                     /protein_id="HAP3137457.1"
                     /translation="MFFKKNLTTAAICAALSVAAFSAMATDSTDTELTIIGEYTPGAC
                     TPVVTGGGIVDYGKHHNSALNPTGKSNKLVQLGRKNSTLNITCTAPTLIAVTSKDNRQ
                     STIVALNDTSYIEKAYDTLVDMKGTKNAFGLGSAPNGQKIGAASIGIDRSNGGIHAAD
                     DTGEIPVDLIQTDHWSAATPTWKASSNGAFCSLTSCSAIERGYSVAKTGELTPVAITA
                     VTFPLLIDAAVNDNTILGSDETIKLDGNVTISVQYL"
     gene            967..1641
                     /locus_tag="IT892_004332"
     CDS             967..1641
                     /locus_tag="IT892_004332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HAP3137458.1"
                     /translation="MLRHITFTVFITTSMNTLATGMVPETSVLLVDEKRGEASINIKN
                     TDDHPSLLYTTIVDLPESNKSIRLIPTQPVIRVEAGQVQQVRFLLQATVPLQSEELKR
                     VTFEGIPPKDDKSSRVTVSIRQDLPVLIHPASLPEERETWKFLEWRKNGDQIEISNPS
                     NYVVRMTLQFKTLPSGKTGAINKTYFLPHTSTTTALTNATDTKVEFYPASRYGYRGNK
                     YVTDLK"
     gene            1662..4043
                     /locus_tag="IT892_004333"
     CDS             1662..4043
                     /locus_tag="IT892_004333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HAP3137459.1"
                     /translation="MLKKTLLAYTIGFAFSPPANADGIEIAAVDFDRETLKSLGVDPN
                     ISHYFSRSARFLPGEYSLIVSVNGEKKGNIATRFDENGDICLDQAFLQQAGLKIPSEE
                     KNGCYDYILSYPGTTITPLPNQEALDIIVSPQAIIPIGLDLTNAATGGTAALLNYSLM
                     SSRAEFSNGSSDYSQAALEGGININDWMLRSHQFLTQTNGTFSNQNSSTYLQRTFTDL
                     KTLMRAGEVNLNNSVLEGASIYGIEIAPDNALQTSGSGVQVTGIANTSQARVEIRQQG
                     VLIHSILVPAGAFTIPDVPVRNGNSDLNVTVVETDGSSHNYIVPSTLFNQHVESFQGY
                     RFAIGRVDDDYDESPWVISASSGWNLTRWSAMNGGVIVAENYQAASIRSSLVPLPDLT
                     VSSQISTSQDTKDSLQGQKYRLDANYNLPFSLGLTTSLTRSDRHYRELSEAIDDDYTD
                     PTKSTYALGLNWSNSILGGFNISGYKTYSYDGDNDSSNLNINWNKAFKHATVSVNWQH
                     QLSASENNEDDGDLFYVNISIPFGRSNTATLYTRHDDHKTHYGTGVMGVVSDEMSYYV
                     NAERDHDERETSLNGSISSNLHYTQVSLAAGASGSDSRTYNGTMSGGIAVHDQGVTFS
                     PWTINDTFAIAKMDNNIAGVRITSQAGPVWTDFRGNAVIPSIQPWRTSGVEIDTASLP
                     KNVDIGNGTKMIKQGRGAVGKVGFSAITQRRALLNITLSDGKKLPRGVAIEDSEGNYL
                     TTSVDDGVVFLNNIKPDMVLDIKDEQQSCRIHLTFPEDAPKDVFYETATGECQ"
     gene            4040..4585
                     /locus_tag="IT892_004334"
     CDS             4040..4585
                     /locus_tag="IT892_004334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137460.1"
                     /translation="MKRIITGCLLLNFAMAAQAECNISSSIQNIDYGKRSAAMRQVDR
                     GKTTQLADRTITLVMQCDQDAHIRVQLNTANISNNGFGFGPNGSLNLIASDAFSGSNN
                     LDLALASGKNDNPGSTGTASISTSPNNWLVFMQNGQEVVIDSGKSVSLTLTMAPAFKD
                     EGELTDMTDITGNLTVLVEAK"
     gene            4582..5298
                     /locus_tag="IT892_004335"
     CDS             4582..5298
                     /locus_tag="IT892_004335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1120 domain-containing protein"
                     /protein_id="HAP3137461.1"
                     /translation="MNNVKLLIAGSAFFAMSAQAADRVSIDVKVTLEAAACTPILSNG
                     GVVNFGSHSVNRLSTQHYTQIGTRNINMTITCESATGIAITARDTRMDSMTTGKDSGG
                     QSGVKYTLNGGGYISQTTRLFGLGKTKDNKNIGSYAVLIDSNNISASNGSQTLAVSIA
                     GADAVITGQKRAWQTLTAYPLAVDQSYYYTFVKPGETTPTPVTNAIIPLQVSASIAND
                     LGGSEKIELDGKAVISVVYL"
     gene            5483..>5716
                     /locus_tag="IT892_004336"
     CDS             5483..>5716
                     /locus_tag="IT892_004336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 domain-containing protein"
                     /protein_id="HAP3137462.1"
                     /translation="MESLSEGTTAGYQHIHDGIIHLVDSARTETVRSVNALMTATYQE
                     IGRRIVEFEQGGEARAAYGAQLIKRLSKDLCLRY"
BASE COUNT         1725 a         1277 c         1257 g         1457 t
ORIGIN      
        1 aaataaattt gttattaagg atatgttcat atgtttttca aaaagaacct cacaacagct
       61 gctatttgtg cagcactttc tgttgcagca ttcagtgcca tggcaacaga ttcaactgat
      121 acagaattaa ctatcatcgg cgagtatacc cctggtgcat gtaccccagt tgttacgggc
      181 ggcggcattg ttgactatgg gaaacatcat aacagtgcgc tgaatccgac cggtaaaagt
      241 aataaactgg ttcaactggg ccgcaaaaac agcacattaa atataacctg cacagcacca
      301 acgctaattg ctgtaacctc caaggataac cgtcagtcga ccattgtagc gttaaacgac
      361 acatcctata ttgaaaaagc ttatgatact ctcgtagata tgaagggaac gaaaaacgcc
      421 tttggtttag gttctgcgcc taatggacaa aaaattggcg ctgcatccat tggtattgac
      481 aggtctaatg gtgggattca cgcggcggac gatacaggtg aaattcctgt cgacctgatt
      541 caaactgacc actggtcagc agcgaccccc acatggaaag cctcatctaa tggcgcattc
      601 tgctcgctga caagttgctc agcaatcgag cgcggttatt ctgttgcaaa aacaggggaa
      661 ctgacacctg ttgccattac agcggtcacc ttcccgttac tgattgatgc tgcggtaaat
      721 gacaatacta ttcttggttc tgatgaaacg atcaaactgg atggtaacgt cactatcagc
      781 gttcagtatt tataagaact tgtaatacag tttttatttt tacgcattaa ccagttagct
      841 ataactcgga cagattatgc cctatgacat ggtctgtctt aatcaatctc atcgcaaaca
      901 gtgcataaca tatattaaca atatgtttct gcgttattta tcattattac aggagtttta
      961 atttaaatgc tcagacacat tacattcact gtatttataa caacatcaat gaatacctta
     1021 gccacaggga tggttcctga aacatcagta ttgctggttg atgaaaagcg tggtgaagct
     1081 agtattaata ttaagaatac agatgatcat ccttcattgc tttacaccac cattgttgat
     1141 ttgcctgaaa gcaataaatc aattcgttta atcccgactc agcccgttat tcgtgttgaa
     1201 gccggtcaag tacaacaggt tcgattttta cttcaggcga ctgttcctct gcaatcagaa
     1261 gagctgaaac gcgtaacgtt cgaaggtatt ccaccaaaag atgacaagag cagcagagtt
     1321 actgtttcaa ttcgtcagga tctacctgta ctgatccacc cggcttccct gccggaagag
     1381 cgagagacct ggaaattcct ggaatggcgt aaaaatggcg accaaattga gattagcaac
     1441 cccagtaatt atgtcgttcg tatgacctta caatttaaaa cgctcccttc aggaaaaacg
     1501 ggggctataa ataagaccta ttttctacca cacaccagta caactactgc attaacaaac
     1561 gctacggata caaaagtcga gttttaccca gccagccgat atggttatcg cggtaataaa
     1621 tatgtcactg acttaaaata actttgcctg gagcgacaag gatgttaaaa aaaacgttac
     1681 tggcctacac cattggtttt gccttttctc ccccagccaa tgcagatggt atagagattg
     1741 ccgctgttga ttttgatcgg gaaacattaa aatcactagg tgtagatcct aatatatcgc
     1801 attatttttc ccgttcagcc cgttttttgc caggtgaata ttcactgata gtatcagtaa
     1861 atggcgaaaa aaaaggcaac attgctacgc gctttgatga aaatggcgac atttgtcttg
     1921 atcaggcatt tctgcaacaa gccggtttaa aaattccttc tgaagaaaaa aatggctgtt
     1981 acgactatat attgtcctac ccgggtacca caatcacacc attacctaac caggaagcgt
     2041 tagatattat cgtttcacca caggcgatca ttcccatagg gttggatctc acaaacgcag
     2101 caactggtgg aacagctgcg ctgctaaact actctctgat gagcagccgt gcagaatttt
     2161 ctaatgggag ttcggactac tcccaggctg cacttgaagg cgggattaat attaatgact
     2221 ggatgttacg cagccatcag ttccttacac aaacaaatgg cacattcagt aaccagaact
     2281 cgtcaaccta ccttcaacgt acctttacag atcttaaaac actcatgcga gcaggtgaag
     2341 ttaacctcaa taatagcgtg ttggaaggag ccagtattta cggtatcgaa atcgcaccgg
     2401 acaacgcatt gcaaaccagc ggcagtggtg tgcaagttac tggtatagcc aacacctctc
     2461 aggctcgtgt cgagattcgt caacaaggag ttttaattca ttccattctg gttcctgcgg
     2521 gcgcattcac tatccctgat gtacctgttc gcaatggtaa tagtgatctt aatgtcaccg
     2581 ttgtcgaaac agacggtagt tcgcacaact atattgttcc ctccaccctg tttaatcagc
     2641 atgtagaaag cttccagggt tatcgcttcg cgatagggcg ggtagacgat gactatgacg
     2701 aatcaccttg ggtaattagt gcatcgagcg gatggaatct gacacgctgg agtgcaatga
     2761 acggcggcgt tatcgtagca gaaaattatc aggcggcatc aatccggtcg agtctggttc
     2821 ccctgcccga tttaacagtg agcagccaaa ttagtacatc gcaggatacg aaagactcac
     2881 tgcaaggaca gaaatatcgt cttgacgcga actacaatct cccattttca cttgggctaa
     2941 caaccagcct cactcgatct gatcgccatt atcgcgaact gtctgaagcg attgatgatg
     3001 attataccga tccgactaaa agcacttatg cgcttggttt aaactggtct aactccattc
     3061 tgggtggttt caacatcagt ggctataaaa catatagtta cgacggtgac aatgactcaa
     3121 gcaaccttaa tattaactgg aacaaagcgt tcaaacacgc cacggtttcc gtcaactggc
     3181 agcatcaact tagtgcttca gaaaataatg aagacgatgg tgatctgttc tacgtcaaca
     3241 tcagtattcc atttggcaga tcaaacaccg ccacactgta tactcgccat gacgatcata
     3301 aaacccacta tggtactggt gtcatgggag tcgtctcaga tgagatgtcc tactatgtga
     3361 atgctgaacg agatcacgac gaacgtgaaa cgagcttgaa cggcagtatc agttccaatc
     3421 tccattacac ccaagtcagc cttgccgcag gagcaagcgg cagtgatagc cgtacttaca
     3481 acggtacgat gtcaggtggt attgccgtac atgatcaggg agtgaccttt tcaccgtgga
     3541 ctatcaatga cactttcgcc atcgcaaaaa tggataacaa tattgcaggt gtcagaatta
     3601 catctcaggc aggcccagta tggacagatt ttcggggtaa tgccgtcatt ccatcaatcc
     3661 agccgtggcg aacatcagga gttgagatcg ataccgccag cttgccaaaa aatgtcgata
     3721 tcggtaacgg cacaaaaatg atcaaacaag gccgtggtgc agtagggaaa gtcggattca
     3781 gtgcgataac acaacgccgt gcattactca atatcacact ttccgacggc aaaaaactgc
     3841 ccagaggcgt tgcgattgaa gatagtgaag gcaactatct gacaacatca gtggatgacg
     3901 gtgttgtatt cctcaataac atcaaaccgg acatggtgct agatataaaa gatgagcagc
     3961 aatcatgccg tattcacctt acattcccag aagatgcacc aaaagatgtg ttctatgaga
     4021 cagcaacagg agagtgccaa tgaaacggat aataacagga tgcctgctgc tgaacttcgc
     4081 catggccgct caggcagagt gtaatatctc cagtagcata caaaatatcg actatggcaa
     4141 acgaagtgct gccatgcgcc aagttgaccg gggtaaaaca acacaattag cagacagaac
     4201 aatcacgctg gtaatgcaat gcgatcagga cgctcatatt cgtgttcagt tgaataccgc
     4261 taatatttcc aacaacggat ttggatttgg cccgaatggt tcattaaatc tgatcgccag
     4321 cgatgcattt tcaggtagta acaatctcga cctggcgtta gccagtggca aaaatgacaa
     4381 tccgggcagc acaggaacag catcaattag tacttccccc aataattggc tggtgtttat
     4441 gcaaaatggt caagaagtgg taattgatag cggtaaaagc gttagcctca cactgacaat
     4501 ggctccagct tttaaggatg aaggggaact aaccgacatg acagatatta caggcaatct
     4561 gacggtcctg gtggaggcaa aatgaacaat gtaaaattac tgattgccgg aagtgccttt
     4621 tttgccatgt cagcgcaagc cgctgataga gtatcaattg acgttaaggt gactctggaa
     4681 gctgcagctt gtactccaat actaagcaac ggcggagttg ttaacttcgg tagtcattca
     4741 gtcaatagac tttcaacgca gcactacaca cagattggaa cacgtaatat taatatgact
     4801 ataacttgcg aatccgctac cggcattgcg attaccgctc gtgatacacg aatggatagt
     4861 atgaccaccg gaaaagatag tgggggtcag agtggtgtaa aatatacctt aaatggcgga
     4921 ggttatatta gccagacaac gcgcttattc ggcttaggga aaacaaaaga taataaaaat
     4981 atcggtagtt atgccgtgtt aattgatagc aacaacatta gtgccagcaa tggtagccag
     5041 acgttagctg tatcaatagc aggtgcagat gccgtcataa cagggcaaaa aagagcatgg
     5101 caaacgctca ccgcttatcc gcttgcagtc gatcaaagct attattacac ctttgtaaaa
     5161 ccaggtgaaa caaccccaac tcctgtaacg aacgccatta taccgcttca ggtgagcgca
     5221 tctatcgcga atgatttagg cggttcagaa aaaatcgaac ttgatgggaa agctgtgata
     5281 agcgtagtct acttgtgata acaatgccgg acaggagtac tatcaggcat tcgttttata
     5341 cgatcggtta atgtttcagg aaagctcttc gcatatcttg gggaaagtaa atgtaatacg
     5401 ctgttcttaa ttgttcagtg ctcacccccc agagtatagc tcattccatt attcaactta
     5461 gctccatata aagggacaga taatggaatc gctctcagaa ggaaccacag caggctacca
     5521 gcatatccac gacggtatta ttcatctggt cgatagcgcc cggacggaaa cggtacgtag
     5581 cgttaacgcg ttaatgaccg cgacgtacca ggaaattggc cgacgaattg tcgaatttga
     5641 acaaggtggc gaggccaggg ctgcgtatgg tgcgcagcta atcaagcgac tatcaaagga
     5701 tttatgtcta aggtat
//
LOCUS       DACAOP010000174         5708 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.175, whole genome shotgun sequence.
ACCESSION   DACAOP010000174 DACAOP010000000
VERSION     DACAOP010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5708
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.175"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(105..725)
                     /gene="entD"
                     /locus_tag="IT892_004337"
     CDS             complement(105..725)
                     /gene="entD"
                     /locus_tag="IT892_004337"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415115.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /protein_id="HAP3137463.1"
                     /translation="MKTTHTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGR
                     KRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVWPAEVYGSISHCGTTALAVVSRQ
                     PIGIDIEEIFSVQTARELTDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKASEI
                     QTDAGFLDYQIISWNKQQVIIHRENEMFAVHWQIKEKIVITLCQHD"
     gene            complement(900..3140)
                     /gene="fepA"
                     /locus_tag="IT892_004338"
     CDS             complement(900..3140)
                     /gene="fepA"
                     /locus_tag="IT892_004338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore enterobactin receptor FepA"
                     /protein_id="HAP3137464.1"
                     /translation="MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQN
                     LQAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPE
                     NTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA
                     GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLD
                     KTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYS
                     RQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHT
                     RNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN
                     QQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTP
                     GLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVG
                     QNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSII
                     PEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS
                     ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYITGAGAYTYNEPGRTWYM
                     SVNTHF"
     gene            complement(3145..3309)
                     /locus_tag="IT892_004339"
     CDS             complement(3145..3309)
                     /locus_tag="IT892_004339"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137465.1"
                     /translation="MHLQYRNGAPWEARTLINQLHCVSFRIKGFRGSGMRRVDDDHAR
                     QLQFVAKMQE"
     gene            3383..4585
                     /gene="fes"
                     /locus_tag="IT892_004340"
     CDS             3383..4585
                     /gene="fes"
                     /locus_tag="IT892_004340"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterochelin esterase"
                     /protein_id="HAP3137466.1"
                     /translation="MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEEYS
                     TIKRVWVYITGVTDHHQNSQPQSMQRIAGTNVWQWTTQLNANWRGSYCFIPTERDDIF
                     SVPSPDRLELREGWRKLLPQAIADPLNLQSWKGGRGHAVSALEMPQAPLQPGWDCPQA
                     PEIPAKEIIWKSERLKKSRRVWIFTTGDATAEERPLAVLLDGEFWAQSMPVWPVLTSL
                     THRQQLPPAVYVLIDAIDTTHRAHELPCNADFWLAVQQELLPLVKAIAPFSDRADRTV
                     VAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGQQEGVLLEKLKAGEVSAEG
                     LRIVLEAGIREPMIMRANQALYAQLHPIKESIFWRQVDGGHDALCWRGGLMQGLIDLW
                     QPLFHDRS"
     gene            4588..4806
                     /locus_tag="IT892_004341"
     CDS             4588..4806
                     /locus_tag="IT892_004341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbtH family protein"
                     /protein_id="HAP3137467.1"
                     /translation="MAFSNPFDDPQGAFYILRNAQGQFSLWPQQCVLPAGWDIVCQPQ
                     SQASCQQWLEAHWRTLTPTNFTQLQEAQ"
     gene            4803..>5708
                     /locus_tag="IT892_004342"
     CDS             4803..>5708
                     /locus_tag="IT892_004342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HAP3137468.1"
                     /translation="MSQHLPLVAAQPGIWMAEKLSELPSAWSVAHYVELTGEVDSPLL
                     ARAVVAGLAQADTLRMRFTEDNGEVWQWVDDALTFELPEIIDLRTNIDPHGTAQALMQ
                     ADLQQDLRVDSGKPLVFHQLIQVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCTW
                     LRGEPTPASPFTPFADVVEEYQQYRESEAWHRDAAFWAEQRRQLPPPASLSPAPLPGR
                     SASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAALWLGRLCNRMDYAAGFIFM
                     RRLGSAALTATGPVLNVLPLGIHIAA"
BASE COUNT         1250 a         1545 c         1501 g         1412 t
ORIGIN      
        1 atccccgcat atccggttgt caggtcagga tggtaaggca cctgctttac actttcgccc
       61 gtggtcagtg atggctgcgg gcgaatcgta ccagatgttg tcaattaatc gtgttggcac
      121 agcgttatga ctatcttttc ttttatctgc cagtgcacag caaacatctc attctcacga
      181 tgaatgatga cctgctgttt attccagcta attatctgat agtccagaaa acctgcatca
      241 gtttggatct cacttgcctt aaatgcgctc tctttggcgg aaaatgccag tgtcagcgcc
      301 agagaaaagg ctaaaccgca gtctgcgagt cgctcgtgtt ccgctggtgt aataatgttg
      361 tctgtcaatt ctcttgcggt ttgtacagaa aaaatttctt ctatatcaat gccaatcggt
      421 tgacgagata ccacggctaa tgccgtagtc ccacagtggc taatactgcc gtatacctcc
      481 gcaggccaga caggttggcg tagctcgccg attgcgggca cacatttata gccatattcc
      541 cgcaaagcat aaacagcagc gatccgtccg gctaaatgct ctgttttacg tttacgtcca
      601 gcgtgttgca gttgtgcgta gtgcggcagc cagagtaaat cctgctcaca aaaattcgcc
      661 ggatcgaact caacaaaatg cagcgtatgt ccggcaaagg ggagggaggt atgcgtagtt
      721 ttcatatcga ccatattcga gactgatgac aaacgcaaaa ctgcctgatg cgctacgctt
      781 atcaggccta catggtcctg caatatattg aattggcaag atttttgtag gccggataag
      841 gcgttcacgc cgcatccggc atgaacgacg cgcactttgt caacaatctg acgttagcat
      901 cagaagtggg tgtttacgct catataccac gtacgtcccg gctcgttata ggtatacgcc
      961 ccggcaccgg tgatatagtt ggcccctgcc aaatcgcccg tggtctgggc attacccgca
     1021 cgccacaaac gtttgtcgaa cagattgtcc acgccgccgg tcagactgac attcttcgtc
     1081 acatcccagg tcgcgctcag gccaacaatg ctgtaaggac taatttcttt ggtttccggt
     1141 ccaaccgctg gctgaccttt atagttgtac ttcttcggct gctgcttgcc gtaccaggtg
     1201 aaggtcgttt gcatcgacaa atcttcccgt gcctgccagc tcagcgttga gttcaacgta
     1261 tactccggga tgatcgacaa acggtcgccc gtggttttgt tttcactctt cagcatataa
     1321 gtgatgttat tggtccacat caccgtttcg ctaaccggta cgtttaacga tccttccaga
     1381 ccttcaacca ccgctttcgg cacgttatcc cactgataga gatcggtgcc gactgcgttt
     1441 tgccctacag ccacatagcc cgcttcaatc ttattgcgat aatcgttacg gaaccaggtg
     1501 acgcccgcca gccacccgtc gcgtttgaac tccagaccaa tctctttgtt gatgctggtt
     1561 tctgctttca ggtcatcgtt accttgcaga tagcagccgc ccgcgctggc atagcaaccc
     1621 tgacctttac tgtagagaat gtagttcggg ttagtctggt acaggctcgg cgctttataa
     1681 gcacgggcga tgcccatttt cagcgtgaag tcatcgccta aaccttgcga tatgttcagc
     1741 gccgggctcc agttattgcc gacaatactg tgatgatcga aacgcagccc cggcgttacg
     1801 atggtgctgt cagtcagctc catgttgttt tcggcaaaca gcgagaaaat ttctgctttt
     1861 gaatacgggc tacggtcggt ggtactcacg ccatcaatag cgccaccggt attcgttccg
     1921 gtcagtgcct gggtgttgga acttaagtcc ttcatccgtt gctgattcca ctccgtaccc
     1981 agcgtcagcg tctggttaac gaggaaatca atcggcaggt taacttcgct gtgcagcatc
     2041 acgtcatcaa gatcgatatc gacgaaatcc tgtgtcgctt tttcgttaaa tttcccttcg
     2101 gtaccgcccg ccagaccttc cggaatacgc gagttacggg tgtgttcgta ctgcacccag
     2161 ttgctggtgg tcacgccgtt atcccagcca ccgttccagg tcagcgcgta gttctggcga
     2221 tacagacggt tggtttcatc gccatatttc gagcgggtat aggaatcgga gttggtattc
     2281 tgggtgtcgc ccgcatacag gttaccctgg cggctgtaac ctgcttccag ttccagcgat
     2341 tgcaatggcg cgaaatccca gcgcaccacg ccattaatat ctttgttgat taccccttcg
     2401 cgcccggctg gtaacgtcgt ggcatacgtt ccggcacgcg cggactgatg gccctggttg
     2461 atatcccacg cgtcagcctg ggttttgtcg aggttgccat acaaacggaa gctgaattcg
     2521 tcgcccagcg gaccggtcag gctaaagtta gtgcgtttgg tggcaccttc ctctttatgt
     2581 tctggcgcat tgaaatatgc gtcccaggag ccgtgccact cgccgctgcc ttttttggta
     2641 atgatgttaa ccacgccgcc cgccgcgccg ttgccataac gcgcagctgc cggaccacgc
     2701 agaacttcaa tacgttcaat catttcaggt ggcacccagg aagtatcacc acgggtatcg
     2761 cgctcgccac gccagccctg acgcaccgag ttacggctgc ttaccggctt gccgtcaatc
     2821 aaaatcagcg tgttttccgg acccataccg cgaatatcaa tctgtcggtt attcccacgc
     2881 tgaccactgg tggagttacc ggtcaggtta acgcctggca tggtacggat gatctccgac
     2941 acatcgcggg caaccgggtt tttgcggatt tcatctgcgg tgatggtcga aacgccaggc
     3001 gcctgtaagt tctgctcggc ggcggtaacg acaatagtat cgtcatgtga aacaggagta
     3061 tcggtcggct cttgtgcctg cgctacccca taaatcccca gattgaccaa caaggccagg
     3121 gaatgaatct tcttgttcat tgttttattc ctgcattttt gccacgaatt gcaactgtcg
     3181 ggcatggtcg tcatcaacac gacgcatccc gctaccgcga aaacctttga tcctgaaaga
     3241 cacgcagtgc agttggttaa ttaatgtccg cgcttcccac ggcgcgccat tacggtattg
     3301 caaatgcaaa tagttatcaa taatattatc aatatatttc tgcaatcaat gaaaaattgc
     3361 acagtaaaca tggggttatg gtgtgacggc gttaaaagta ggaagtgaga gctggtggca
     3421 gtcgaaacat ggcccggaat ggcagcgtct gaatgacgaa atgtttgagg tcactttctg
     3481 gtggcgtgat ccccaaggtt ctgaagaata ctcgacgata aagcgcgtat gggtctacat
     3541 cactggtgtg accgatcacc atcagaacag ccagccccag tcgatgcagc gaattgcagg
     3601 cactaacgtc tggcagtgga cgacacaact caatgccaac tggcgcggca gctactgctt
     3661 tattcccacc gaacgcgatg acattttttc tgtaccatcc cccgatcgcc tcgaattgcg
     3721 cgaaggctgg cgaaaactat taccccaggc gatagccgat ccgctgaacc tacaaagctg
     3781 gaaaggcggg cgagggcacg ctgtttctgc actcgaaatg ccgcaagcgc ctctgcaacc
     3841 gggatgggat tgtccgcaag cgccagaaat acctgccaaa gaaattatct ggaaaagtga
     3901 acggttgaaa aagtcacggc gtgtatggat ttttaccacc ggcgatgcaa cagcagaaga
     3961 acgcccgctg gcagttttgc tcgatggcga attttgggcg caaagtatgc ccgtctggcc
     4021 agtgctgact tcgctgaccc atcgtcagca acttcctccc gccgtgtatg tgttgatcga
     4081 cgctatcgac accacgcacc gcgcccacga actgccgtgt aatgcggatt tctggctcgc
     4141 agtacagcaa gagttattac ccctggtgaa agctattgcc ccttttagcg atcgtgccga
     4201 tcgcaccgtg gttgccgggc agagttttgg tgggctttcc gcgctgtatg ccggactgca
     4261 ctggcctgaa cgctttggct gtgtattaag ccagtcagga tcgtactggt ggccgcatcg
     4321 gggcgggcag caagagggcg tgttacttga aaagctaaaa gctggtgaag ttagcgccga
     4381 aggtctgcgc attgtgctgg aagcgggtat tcgcgagccg atgatcatgc gggccaatca
     4441 ggcgctgtat gcgcaattac accccataaa agaatccatt ttctggcgtc aggttgacgg
     4501 cggacatgat gcgctttgtt ggcgcggtgg cttgatgcag gggctaatcg acctctggca
     4561 accacttttc catgacagga gttgaatatg gcattcagta atcccttcga tgatccgcag
     4621 ggagcgtttt acatattgcg caatgcgcag gggcaattca gtctgtggcc gcaacaatgc
     4681 gtcttaccgg caggctggga cattgtgtgt cagccgcagt cacaggcgtc ctgccagcag
     4741 tggctggaag cccactggcg tactctgaca ccgacgaatt ttacccagtt gcaggaggca
     4801 caatgagcca gcatttacct ttggtcgccg cacagcccgg catctggatg gcagaaaaac
     4861 tgtcagaatt accctccgcc tggagcgtgg cgcattacgt tgagttaacc ggagaggttg
     4921 attcgccatt actggcccgc gcggtggttg ccggactagc gcaagcagat acgctgcgga
     4981 tgcgttttac ggaagataac ggcgaagtct ggcagtgggt cgatgatgcg ctgacgttcg
     5041 aactgccaga aattatcgac ctacgaacca acattgatcc gcacggtact gcgcaggcat
     5101 taatgcaggc ggatttgcaa caagatctgc gcgtcgatag cggtaaacca ctggtctttc
     5161 atcagctgat acaggtggcg gataaccgct ggtactggta tcagcgttat caccatttgc
     5221 tggtcgatgg ctttagtttc ccggccatta cccgccagat cgccaatatt tactgcacat
     5281 ggctgcgtgg cgaaccaacg cctgcttcgc catttacgcc tttcgctgat gtagtggaag
     5341 agtaccagca ataccgcgaa agcgaagcct ggcaccgtga tgcggcattc tgggcagaac
     5401 agcgtcgtca actgccgccg cccgcgtcac tttctccggc acctttaccg gggcgcagcg
     5461 cctcggcaga tattctgcgc ctgaaactgg aatttaccga cggggaattc cgccagctgg
     5521 ctacgcaact ttcaggtgtg cagcgtaccg atttagccct tgcgctggca gccttgtggc
     5581 tggggcgatt gtgcaatcgt atggactacg ccgccggatt tatctttatg cgtcgactgg
     5641 gctcggcggc gctgacggct accggacccg tgctcaacgt tttgccgttg ggtattcaca
     5701 ttgcggcg
//
LOCUS       DACAOP010000175         5523 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.176, whole genome shotgun sequence.
ACCESSION   DACAOP010000175 DACAOP010000000
VERSION     DACAOP010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5523
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.176"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            66..230
                     /locus_tag="IT892_004343"
     CDS             66..230
                     /locus_tag="IT892_004343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmiA family putative membrane protein"
                     /protein_id="HAP3137469.1"
                     /translation="MLISDGDYMRLAMPSGNQEPRRDPELKRKAWLAVFLGSALFWVV
                     VALLIWKVWG"
     gene            233..400
                     /locus_tag="IT892_004344"
     CDS             233..400
                     /locus_tag="IT892_004344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137470.1"
                     /translation="MVGQEQLESSPLCQHSDNETETKRECSVVIPDDWQLTSQQQAFI
                     ELFAEDDQPKQ"
     gene            514..609
                     /locus_tag="IT892_004345"
     CDS             514..609
                     /locus_tag="IT892_004345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137471.1"
                     /translation="MINTNMKYWSWMGAFSLSMLFWAELLWIITH"
     gene            773..3448
                     /gene="acnA"
                     /locus_tag="IT892_004346"
     CDS             773..3448
                     /gene="acnA"
                     /locus_tag="IT892_004346"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HAP3137472.1"
                     /translation="MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSLKV
                     LLENLLRWQDGNSVTEEDIHALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAA
                     MREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFL
                     KWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMI
                     NGLGVLGWGVGGIEAEAAMLGQLVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLR
                     KHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAVTLDYMRLSGRSE
                     DQVELVEKYAKAQGMWRNPGDEPIFTSTLELDMNDVEASLAGPKRPQDRVALPDVPKA
                     FAASNELEVNATHKDRQPVDYVMNGHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLL
                     AKKAVTLGLKRQPWVKASLAPGSKVVSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNS
                     GPLPDPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAGNMNI
                     NLASEPIGHDRKGDPVYLKDIWPSAQEIARAVEQVSTEMFRKEYAEVFEGTAEWKGIN
                     VTRSDTYGWQEDSTYIRLSPFFDEMQATPAPVEDIHGARILAMLGDSVTTDHISPAGS
                     IKPDSPAGRYLQGRGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMVPGVEGGMTR
                     HLPDSDVVSIYDAAMRYKQEQTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESF
                     ERIHRSNLIGMGILPLEFPQGVTRKTLGLTGEEKIDIGDLQNLQPGATVPVTLTRADG
                     SQEVVPCRCRIDTATELTYYQNDGILHYVIRNMLK"
     gene            complement(3512..4102)
                     /gene="ribA"
                     /locus_tag="IT892_004347"
     CDS             complement(3512..4102)
                     /gene="ribA"
                     /locus_tag="IT892_004347"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HAP3137473.1"
                     /translation="MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHT
                     PVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKI
                     RAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTE
                     AGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK"
     gene            4272..5036
                     /gene="pgpB"
                     /locus_tag="IT892_004348"
     CDS             4272..5036
                     /gene="pgpB"
                     /locus_tag="IT892_004348"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase B"
                     /protein_id="HAP3137474.1"
                     /translation="MRSIARRTAVGAALLLVMPVAVWISGWRWQPGEQSWLLKAAFWV
                     TETVTQPWGVITHLILFGWFLWCLRFRIKAAFVLFAILAAAILVGQGVKSWIKDKVQE
                     PRPFVIWLEKTHHIPVDEFYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFP
                     SGHTMFAASWALLAVGLLWPRRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLI
                     SWALVAVATWLAQRICGPLTPPAEENREIAQREQES"
     gene            5185..5493
                     /gene="lapA"
                     /locus_tag="IT892_004349"
     CDS             5185..5493
                     /gene="lapA"
                     /locus_tag="IT892_004349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA"
                     /protein_id="HAP3137475.1"
                     /translation="MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTL
                     LAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVVPHSSAAKE
                     "
BASE COUNT         1342 a         1296 c         1466 g         1419 t
ORIGIN      
        1 ttttgactaa agtttcttta ggatttgtct catcgtatga ttaattacac caatcgttca
       61 acgtcttgct gataagtgat ggcgattata tgaggttagc aatgccttct ggaaatcagg
      121 aaccccgccg cgatcctgaa ttaaaacgta aagcctggct ggcggttttt cttggttctg
      181 cacttttctg ggtggttgtc gcactgctga tttggaaagt gtggggataa ctatggtcgg
      241 tcaggagcaa ctggagtcgt caccattatg ccagcatagt gacaatgaaa cagaaacgaa
      301 acgggaatgt tccgtcgtta ttccagacga ctggcaacta acatcgcagc agcaagcctt
      361 tatagaactg tttgctgaag atgatcagcc gaaacaataa ttatcatcat tcttattacc
      421 catttttaat gaattaaagg gcttttaata caccgcagca ataacagctt gagttatctc
      481 aacacaaaat aataaccgtt aagggtgtag cctatgatca acacaaatat gaaatattgg
      541 tcctggatgg gcgcgttttc tctgtcgatg ctcttctggg ccgaactcct ctggatcatt
      601 actcactgat ccttgacccc gctgcggcgg ggttgtcatt tgctttgcca caaggtttct
      661 cctcttttat caatttgggt tgttatcaaa tcgttacgcg atgtttgtgt tatctttaat
      721 attcaccctg aagagaatca gggcttcgca accctgtcat taaggaggag ctatgtcgtc
      781 aaccctacga gaagccagta aggacacgtt gcaggccaaa gataaaactt accactacta
      841 cagcctgccg cttgctgcta aatcactggg cgatatcacc cgtctaccca agtcactcaa
      901 agttttgctc gaaaacctgc tgcgctggca ggatggtaac tcggttaccg aagaggatat
      961 ccacgcgctg gcaggatggc tgaaaaatgc ccatgctgac cgtgaaattg cctaccgccc
     1021 ggcaagggtg ctgatgcagg actttaccgg cgtacctgcc gttgttgatc tggcggcaat
     1081 gcgcgaagcg gttaaacgcc tcggcggcga tactgcaaag gttaacccgc tctcaccggt
     1141 cgacctggtc attgaccact cggtgaccgt cgatcgtttt ggtgatgatg aggcatttga
     1201 agaaaacgta cgcctggaaa tggagcgcaa ccacgaacgt tatgtgttcc tgaaatgggg
     1261 aaagcaagcg ttcagtcggt ttagcgtcgt gccgccaggc acaggcattt gccatcaggt
     1321 taacctcgaa tatctcggca aagcagtgtg gagtgaattg caggacggtg aatggattgc
     1381 ttatccggat acactcgttg gtactgactc gcacaccacc atgatcaacg gccttggcgt
     1441 gctggggtgg ggcgttggtg ggatcgaagc agaagccgca atgttaggcc agctggtttc
     1501 catgcttatc ccggatgtag tgggcttcaa acttaccgga aaattacgtg aaggtattac
     1561 cgccacagac ctggttctca ctgttaccca aatgctgcgc aaacatggcg tggtggggaa
     1621 attcgtcgaa ttttatggtg atggtctgga ttcactaccg ttggcggatc gcgccaccat
     1681 tgccaatatg tcgccagaat atggtgccac ctgtggcttc ttcccaatcg atgctgtaac
     1741 cctcgattac atgcgtttaa gcgggcgcag cgaagatcag gtcgagttgg tcgaaaaata
     1801 tgccaaagcg cagggcatgt ggcgtaaccc gggcgatgaa ccaattttta ccagtacgtt
     1861 agaactggat atgaatgacg ttgaagcgag cctggcaggg cctaaacgcc cacaggatcg
     1921 cgttgcactg cccgatgtac caaaagcatt tgccgccagt aacgaactgg aagtgaatgc
     1981 cacgcataaa gatcgccagc cggtcgatta tgttatgaac ggacatcagt atcagttacc
     2041 tgatggcgct gtggtcattg ctgcgataac ctcgtgcacc aacacctcta acccaagtgt
     2101 gctgatggcc gcaggcttgc tggcgaaaaa agccgtaact ctgggcctca agcggcaacc
     2161 atgggtcaaa gcgtcgctgg caccgggttc gaaagtcgtt tctgattatc tggcaaaagc
     2221 gaaactgaca ccgtatctcg acgaactggg gtttaacctt gtgggatacg gttgtaccac
     2281 ctgtattggt aactctgggc cgctgcccga tcctatcgaa acggcaatca aaaaaggcga
     2341 tttaaccgtc ggtgcggtgc tgtccggcaa ccgtaacttt gaaggccgta tccatccgct
     2401 ggttaaaact aactggctgg cctcgccgcc gctggtggtt gcctatgcgc tggcgggaaa
     2461 tatgaatatc aacctggctt ctgagcctat cggccatgat cgcaaaggcg atccggttta
     2521 tctgaaagat atctggccat cggcacaaga aattgcccgt gcggtagaac aagtctccac
     2581 agaaatgttc cgcaaagagt acgcagaagt ttttgaaggc acagcagagt ggaagggaat
     2641 taacgtcaca cgatccgata cctacggttg gcaggaggac tcaacctata ttcgcttatc
     2701 gcctttcttt gatgaaatgc aggcaacacc agcaccagtg gaagatattc acggtgcgcg
     2761 gatcctcgca atgctggggg attcagtcac cactgaccat atctctccgg cgggcagtat
     2821 taagcccgac agcccagcgg gtcgatatct acaaggtcgg ggtgttgagc gaaaagactt
     2881 taactcctac ggttcgcggc gtggtaacca tgaagtgatg atgcgcggca ccttcgccaa
     2941 tattcgcatc cgtaatgaaa tggtgcctgg cgttgaaggg gggatgacgc ggcatttacc
     3001 tgacagcgac gtagtctcta tttatgatgc tgcgatgcgc tataagcagg agcaaacgcc
     3061 gctggcggtg attgccggga aagagtatgg atcaggctcc agtcgtgact gggcggcaaa
     3121 aggtccgcgt ctgcttggta ttcgtgtggt gattgccgaa tcgtttgaac gaattcaccg
     3181 ttcgaattta attggcatgg gcatcctgcc gctggaattt ccgcaaggcg taacgcgtaa
     3241 aacgttaggg ctaaccgggg aagagaagat tgatattggc gatctgcaaa acctacaacc
     3301 cggcgcgacg gttccggtga cgcttacgcg cgcggatggt agccaggaag tcgtaccctg
     3361 ccgttgtcgt atcgacaccg cgacggagtt gacctactac cagaacgacg gcattttgca
     3421 ttatgtcatt cgtaatatgt tgaagtaaca actatttgct tgccggttat tttgcttccg
     3481 gcaagcaaat gaattacaca atgcaagagg gttatttgtt cagcaaatgg cccattttct
     3541 cggctttggt atcgagataa tgttcgttat tggggttacg acctacaatc aatggtacgc
     3601 gttcaacaat attaatccct gcttcggtca gaatttcgac ttttttcggg ttattggtta
     3661 acaagcggac ttcattgacg ccaaggagtt tgaacatatc agcgcaaaga gtgaagtcgc
     3721 gctcatcagc ggcgaagcct aactggtggt tagcctctac ggtatcgtaa ccttgatcct
     3781 gcagtgcgta agcgcggatt ttattcagca gaccaatgtt acgaccttcc tgacggtgat
     3841 acagcaaaat accacggcct tcctcggcaa tttgcgtcaa tgccgcttcg agctggaagc
     3901 cacaatcgca gcgcaagctg aacagggcgt caccggtcag acattcggaa tggacgcgcg
     3961 caagtaccgg ggtatgcccg gaaatatcgc catagactag cgcgacatga tcgtgtccgg
     4021 ttgccagttc ttcaaatccc accatcagga aatcgcccca tggggttggc agtttggctt
     4081 ctgccacacg tttaagctgc atgaaattct ccagataatg ctggttctgt attggcttat
     4141 tttgccataa cgagaagggg ttcacctaat cacgacgcgt cgatcgttca cggaatggca
     4201 caaatctgtc aatttttcct ggaactggcg ttttcagtta tgattgtggg acttatcaaa
     4261 aaggagaggc catgcgttcg attgccagac gtaccgcagt gggagctgca ctattgcttg
     4321 tcatgccagt agccgtatgg atttctggct ggcgttggca acctggagaa caaagttggc
     4381 tactaaaagc ggctttttgg gttactgaaa ctgtcaccca gccctggggc gtcattacac
     4441 atttgatttt attcggctgg tttctctggt gtctgcgttt tcgcattaag gctgcctttg
     4501 tattatttgc cattctggcg gccgcaatcc ttgtgggaca aggcgttaaa tcctggatca
     4561 aagacaaagt ccaggaacca cgaccttttg ttatctggct ggaaaaaaca catcatattc
     4621 cggttgatga gttctacact ttaaagcgag cagaacgcgg aaatctagtg aaagaacagt
     4681 tggctgaaga gaaaaatatc ccacaatatt tgcgttcaca ctggcagaaa gagacggggt
     4741 ttgcctttcc ttccggtcac acgatgtttg ctgccagttg ggcactgctg gccgttggtt
     4801 tgctgtggcc gcgtcggcga acgttaacca ttgctatctt gctggtctgg gcaacgggag
     4861 tcatgggaag ccgcctgctg ctcgggatgc attggccacg cgatctggta gtagctacgt
     4921 tgatttcgtg ggcgctggtg gcggtggcaa cgtggcttgc gcaacgaatt tgtgggccat
     4981 taacaccacc tgcggaagaa aatcgcgaaa tagcgcaacg agaacaagaa agttaacgct
     5041 ggttgatttt ccgaatttag cccttaaatc atcaacaatg cgtgtggatg ccatttcgca
     5101 gacggcgcga aaatggtact ttaaagggct attgcggtaa gttgaccata atttattcgc
     5161 tctaaccaca taacgggaag taatgtgaaa tatttactca ttttcttact ggtgttagcg
     5221 atcttcgtga tttcggtcac gttgggtgcg cagaacgatc aacaggtgac gtttaattat
     5281 ctgttagcgc aaggggagta ccgtatttcc acattgctgg cggtattgtt tgctgcgggg
     5341 tttgctatcg gttggttgat ttgtggcctg ttctggctgc gagttcgtgt ttccctggcg
     5401 cgcgctgaac gtaaaataaa gcgactggaa aaccagcttt cacccgcgac tgacgtggct
     5461 gtagtgccgc actcgtcagc ggcgaaggaa taactttcta tgctggagtt gttgtttctg
     5521 ctt
//
LOCUS       DACAOP010000176         5469 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.177, whole genome shotgun sequence.
ACCESSION   DACAOP010000176 DACAOP010000000
VERSION     DACAOP010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5469
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.177"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(13..870)
                     /gene="murI"
                     /locus_tag="IT892_004350"
     CDS             complement(13..870)
                     /gene="murI"
                     /locus_tag="IT892_004350"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418402.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAP3137476.1"
                     /translation="MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLL
                     PDLHYIYAFDNVAFPYGEKSEAFIVERVVAIVTAVQERYPLALAVVACNTASTVSLPA
                     LREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEML
                     GSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVL
                     PEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPGAEQLLPVLQRYGFE
                     TLEKLAVLG"
     gene            complement(815..2659)
                     /gene="btuB"
                     /locus_tag="IT892_004351"
     CDS             complement(815..2659)
                     /gene="btuB"
                     /locus_tag="IT892_004351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent vitamin B12 receptor BtuB"
                     /protein_id="HAP3137477.1"
                     /translation="MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLA
                     PTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDG
                     VRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEI
                     SAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQTDNDGFL
                     SKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRY
                     NGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAG
                     VDWQKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQ
                     TSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVN
                     WRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARN
                     AITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSL
                     WDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF"
     regulatory      complement(2724..2914)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            3028..4128
                     /gene="trmA"
                     /locus_tag="IT892_004352"
     CDS             3028..4128
                     /gene="trmA"
                     /locus_tag="IT892_004352"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HAP3137478.1"
                     /translation="MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHY
                     RMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLR
                     HKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTK
                     IELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELY
                     CGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNG
                     VREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLE
                     TLSQTHKVERLALFDQFPYTHHMECGVLLTAK"
     gene            complement(4168..4527)
                     /locus_tag="IT892_004353"
     CDS             complement(4168..4527)
                     /locus_tag="IT892_004353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YijD family membrane protein"
                     /protein_id="HAP3137479.1"
                     /translation="MKQANQDRGTLLLALVAGLSINGTFAALFSSIVPFSVFPIISLV
                     LTVYCLHQRYLNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIM
                     VFWIGAKMRNRKQEVAE"
     gene            complement(4527..5177)
                     /gene="fabR"
                     /locus_tag="IT892_004354"
     CDS             complement(4527..5177)
                     /gene="fabR"
                     /locus_tag="IT892_004354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor FabR"
                     /protein_id="HAP3137480.1"
                     /translation="MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGI
                     APTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGN
                     NPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVT
                     IVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE"
BASE COUNT         1444 a         1425 c         1326 g         1274 t
ORIGIN      
        1 cattcaacca aatcagccta aaactgccag tttttcgagc gtttcgaagc cgtaacgctg
       61 taaaacgggc aataattgtt cagctcctgg cgtcattgcc atacaaaagg caatattcgc
      121 atcggcagat tttgcatccg gggcttcatg ttctaacaac caggccgttc ggcgagcaat
      181 cgctgcgcca gaatccacca gccgggttcc ctctggcagc acttgtaaca gttcttcttg
      241 tagtagaggg aaatgggtgc aacccaatac aacggtatct ggcggctctt tcattcttaa
      301 ccacgggcgt aggatacgtt ttagtgcatc cagagaaaca tcttcgccat gtagcttcgc
      361 ttcagccaac tcaaccatct ctgccgagcc cagcatttct atctggcatt cattagcgaa
      421 acgcgcgatc agctcatgag tataagaacg tttaactgtt ccgcgggttg ccagtaatcc
      481 gacaatgcca tttgccgtca gacgtgcagc aggtttaatc gccggcacga caccaacaac
      541 cgggaagtcg aacttttcgc gtaatgcagg aagtgaaacg gtactggcag tgttgcaagc
      601 gaccacagcc agcgcaaggg gataacgttc ttgcaccgcg gtgacaattg ccaccactcg
      661 ctcaacaata aacgcttcgc ttttttcgcc atacgggaaa gcgacgttat cgaaagcata
      721 aatgtaatgg agatccggta agagatgccg gatctcgtca tagaccgaca acccaccgac
      781 gccggagtca aacaccagca cggtgggacg tggttcagaa ggtgtagctg ccagacaagg
      841 tgtattcccg tcctgcagtt tggtagccat agactgtctc ataatctttg tcgaacaggt
      901 tggctatttt accacgaact gtcaggtgag aggtgaccgg atacgcaacc gcaagatccc
      961 acaagctcac accgcccatt ttaacggttt gataaggata agatgagtaa tccttatcat
     1021 agcgagtgcc taaatactga taagtaatac cccagtcgaa gtcatacaac tgccagtcga
     1081 gctggtattt cacctgctgt ttagcacggc gtaacaacgg cgtgtcggta atcgcattgc
     1141 gcgcatcgac ataatcataa ctcacagtat gcgtcagtgg tccggtatca aaattggcgg
     1201 tcgcctcgac gcccttaatc cgcgctttcc cttcgttgta atatttcagg gtgtgatcat
     1261 cataatcgat caagtcactg acatcgttac gatatccgga aatacgccag ttcaccccag
     1321 cggttaagcc ttcaaacgcg ccttcccact gtttgctttt ctccgggtcc agattcggat
     1381 ttccgtagaa gccatacagt tgccccagat ttggtgcctt ataagatgtc ccgtaggaag
     1441 caatgaagcg ataaccttcg atgaattccc aaccggcgct ggtttgccag gttccatgac
     1501 gaccaaactg tgagttatcg tcactgcgtg ctgcgccttc aaaggtaaaa tcgccgactt
     1561 gttgcagccc ggtcagatag atgccggtat tacgttgatc atatccatcc tcaacataac
     1621 ctgtacccgg cgtcgtagtc tgtttctgcc agtcgacacc cgcaccaata ctaccgtgac
     1681 caacgatgac attgtttgcc cactggacgg tgtattgctt catctcatcg agcgtcgccg
     1741 acgaatcata acgaccataa tggggatcgt agttgtaatc tttgctatgg ctatagctgg
     1801 taatgagttg tgatttaatc agttcgccgt tatagcgcag cccggcgtcc caactttggc
     1861 tatagagttt acgggtatcg agcaacggtg aaccgggaga ataatacgcg tcataattgg
     1921 tacggttatc atagccatag ccgcgcacaa agccgctcca ggcatcagta aagttatgct
     1981 ccagcgcgcc ataaagcgtt ttacttaaaa aaccatcgtt atctgtctgc gcttgcgttc
     2041 cggtattacc ataggcaaca acatcataac catgagtatg ggcataatcg cccaacagcg
     2101 ttacccgtgt cttatccccc agttgttgct gcgtagagac atcatagttc tgataactat
     2161 tgcttcccca ccctgctgaa atttccgttc cgggttcatc gcgcgtcgtg atgatattca
     2221 ccaccccgcc tattgcatcg gaaccataaa cagcggagcg cggcccacgg atatattcaa
     2281 cacgctggac aagcgcaata gggaactggc taaggtcggc agaaccactc acccccgcca
     2341 gattcaggcg tacgccatca attaacacca acacatgact ggcatttgta ccgcgaataa
     2401 aaatagatga gagctgacct gaaccgccgt tttgggtgat atcgacgccc ggaagacggc
     2461 gcagcacatc attgaccgag gtcgactgcc agcggtcgat atcctgacgg gtcacaacgg
     2521 tggttggtgc aagcacagtg ctgcgcggct gttcaaaacg gttagcagta acgacgagag
     2581 tatccgggct ggtatcctgt gcccaagcgg aaaatgccgt gacggaacac gccgtcagca
     2641 gcgaagcttt tttaatcatt gtaaagcatc cacaatagaa gaaggatgcc gcaggtttca
     2701 tcaatattac gcgatgatga gaaccagatg cgacgttggc cggcaggtct tcgggcttgg
     2761 aggggtatct aagatactaa gagatgatga cttcccaccg aatggcagtg tccgcataac
     2821 gcaatcatcg cacctttcct taccgctgcg cgtcagctcc agattcgcac tggattccct
     2881 attaactcac aggaccggca agtggatgct acaggttgta acaagttact gtccagacgt
     2941 agctcacaaa taggaattca tcaagatctg gacatctgat gagcaatccc tacaatcgcc
     3001 gcgtacttta atttttcagg atacatcatg acccccgaac accttccaac agaacagtat
     3061 gaagcgcagt tagccgaaaa agtggtacgt ttgcaaagta tgatggcacc gttttctgac
     3121 ctggttccgg aagtgtttcg ctcgccggtc agtcattacc ggatgcgcgc ggagttccgc
     3181 atctggcacg atggcgatga cctgtatcac atcattttcg atcaacaaac caaaagccgc
     3241 atccgcgtgg atagcttccc cgccgccagt gaacttatca accagttgat gacggcgatg
     3301 attgcgggtg tgcgtaataa tcccgttctg cgccacaagt tgttccagat tgattacctc
     3361 actacgctga gtaatcaggc ggtggtttcc ctgctatacc ataagaagct ggatgatgag
     3421 tggcgtcagg aagcggaggc cctgcgcgat gcactgcgcg cgcagaatct gaatgtgcat
     3481 ctgattggtc gggcaacgaa aaccaaaatc gagctggatc aggattacat cgatgaacgt
     3541 ctgccggtcg cagggaaaga gatgatctac cgtcaggtag aaaacagctt tacccagccg
     3601 aacgcggcga tgaatattca gatgctggaa tgggcgctgg acgtaaccaa aggctcaaaa
     3661 ggcgatttac tggagctgta ctgcggcaac ggtaactttt cattagcgct ggcgcgtaat
     3721 tttgatcggg tattagccac cgaaatcgct aagccgtcgg ttgctgctgc gcaatacaac
     3781 atcgcagcta accatattga taacgtacaa attattcgta tggcggcaga agaatttact
     3841 caggcgatga atggtgtgcg cgagtttaac cgcctgcaag ggatcgactt aaagagttat
     3901 cagtgcgaaa ccatttttgt cgacccaccg cgcagcggtc tggacagtga aaccgagaaa
     3961 atggtgcagg cgtatccgcg tattttgtac atctcctgta acccggaaac gttatgcaag
     4021 aatctggaaa cattaagcca gacgcacaag gtcgaacgtc tggctctgtt tgatcagttc
     4081 ccctacacgc accatatgga gtgcggcgta ttactgaccg cgaagtaaaa cccatgccgg
     4141 atgcgccagc atccggcata ataccgatta ctcagcaact tcctgcttac ggttacgcat
     4201 cttcgcgcca atccagaaca ccataatgac ggagagtact gccgggaaga agttagagcc
     4261 gatatccgga tattccgcac gaactaccgt gctgtacagc agtacgccga gaataaaaca
     4321 ggcagctgcc agacccggca agcctaccgg catagtgcga ttaagataac gttgatgcag
     4381 gcagtaaacc gtcagcacca gggaaataat cgggaataca gaaaatggca caatggagct
     4441 aaacagcgct gcgaaagtac cattaatcga taagccagca actaacgcca gcagcagcgt
     4501 acctctatct tgatttgctt gtttcattac tcgtccttca catttcccgg aataattgcg
     4561 gttttctctt gttcacggcg ataccagtaa taagcccctt tcgaaatcat tcgcagttgc
     4621 agtaccagtc gctcttctaa ttgccgacgt tgttcgacgc cgacgtccaa cgcctcggca
     4681 cccgcactga agacaattgt caccattgct tcggcttgcg cttcagtaaa cgcacgcggc
     4741 atatggtttt cgagttccag atagtccgca agttccgcaa tgaagtgctg aatttcacgc
     4801 gcaacggcgg cacgaaacgc agcggaggtg ccggagcgtt cccgcaataa taaccggaag
     4861 gcgttaggat tattaccgat gaactccata aatgtggaga ccgaggtgcg gatcacactc
     4921 ccgcctttgg cgatacgctg acgcgcctgg cgcatgagtt ggcgtagcat taaaccgctc
     4981 tcatcaacca tggtcagacc cagttcgtct acgtcgcgga aatgccgata aaaagaggtg
     5041 ggagcaatgc ccgcttcacg cgccacttca cgcaaactca ggctggcgaa gctgcgttca
     5101 gcacttaatt ggctaaatgc ggcttccacc agcgaacggc gggttttttc tttttgttgc
     5161 gctcttacgc ccatcacgat gtctgaatcc ttgccaaaaa tactgctggc actataccag
     5221 agaatgaaca tactggattg ctccagtatt gtgaatgaac ggtaacgcaa taaaacatat
     5281 ttactgcaat tctttggccg gttcttttac gtacagcgga aacctgccgc ttaaacggag
     5341 agtatcgtcg ataaaaatcc aataaaacgt cagggcaaaa gtaagaaaca gacaaagcaa
     5401 aggccgctca ggatatagcc agataaatga cggggatcaa ttggcttacc cgcgataaaa
     5461 tgttaccat
//
LOCUS       DACAOP010000177         5447 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.178, whole genome shotgun sequence.
ACCESSION   DACAOP010000177 DACAOP010000000
VERSION     DACAOP010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5447
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.178"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..604
                     /gene="yiaO"
                     /locus_tag="IT892_004355"
     CDS             <1..604
                     /gene="yiaO"
                     /locus_tag="IT892_004355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter
                     substrate-binding protein YiaO"
                     /protein_id="HAP3137481.1"
                     /translation="KASLEGKGLKVLAYWENGWRDVTNSRAPVKTPADLKGLKIRTNN
                     SPMNIAAFKVFGANPIPMPFAEVYTGLETRTIDAQEHPINVVWSAKFFEVQKFLSLTH
                     HAYSPLLVVINKAKFDGLSPEFQQALVSSAQEAGNYQRKLVAEDQQKIIDGMKEAGVE
                     VITDLDRKAFSDALGNQVRDMFVKDVPQGADLLKAVDEVQ"
     gene            608..2104
                     /gene="lyxK"
                     /locus_tag="IT892_004356"
     CDS             608..2104
                     /gene="lyxK"
                     /locus_tag="IT892_004356"
                     /EC_number="2.7.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-xylulokinase"
                     /protein_id="HAP3137482.1"
                     /translation="MTQYWLGLDCGGSWLKAGLYDREGREAGVQRLPLCALSPQPGWA
                     ERDMAELWQCCMAVIRALLTHSGVSGEQIVGIGISAQGKGLFLLDKNDKPLGNAILSS
                     DRRAMEIVRRWQEDGIPEKLYPLTRQTLWTGHPVSLLRWLKEHEPERYAQIGCVMMTH
                     DYLRWCLTGVKGCEESNISESNLYNMSLGEYDPCLTDWLGIAEINHALPPVVGSAEIC
                     GEITAQTAALTGLKAGTPVVGGLFDVVSTALCAGIEDEFTLNAVMGTWAVTSGITRGL
                     RDGEAHPYVYGRYVNDGEFIVHEASPTSSGNLEWFTAQWGEISFDEINQAVASLPKAG
                     GDLFFLPFLYGSNAGLEMTSGFYGMQAIHTRAHLLQAIYEGVVFSHMTHLNRMRERFT
                     DVHTLRVTGGPAHSDVWMQMLADVSGLRIELPQVEETGCFGAALAARVGTGVYHNFSE
                     AQRDLRHPVRTLLPDMTAHQLYQKKYQRYQHLIAALQGFHARIKEHTL"
     gene            2101..2763
                     /gene="ulaD"
                     /locus_tag="IT892_004357"
     CDS             2101..2763
                     /gene="ulaD"
                     /locus_tag="IT892_004357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAP3137483.1"
                     /translation="MSRPLLQLALDHSSLEAAQRDVTLLKDSVDIVEAGTILCLNEGL
                     GAVKALREQCPDKIIVADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMA
                     QRCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
                     DIGLELSITGGITPADLPLFKDIRVKAFIAGRALAGAANPAQVAGDFHAQIDAIWGGA
                     RA"
     gene            2756..3616
                     /locus_tag="IT892_004358"
     CDS             2756..3616
                     /locus_tag="IT892_004358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418039.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAP3137484.1"
                     /translation="MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDER
                     LSRLDWSAAQRTSLVAAMIETGVGIPSMCLSAHRRFPFGSRDEAVRERAREIMSKAIR
                     LARDLGIRTIQLAGYDVYYEDHDEGTRQRFAEGLAWAVEQAAASQVMLAVEIMDTAFM
                     NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTG
                     QSPGQFRDVPFGEGCVDFVGIFKTLHKLNYRGSFLIEMWTEKAKEPVLEIIQARRWIE
                     ARMQEAGFIC"
     gene            3610..4305
                     /locus_tag="IT892_004359"
     CDS             3610..4305
                     /locus_tag="IT892_004359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase SgbE"
                     /protein_id="HAP3137485.1"
                     /translation="MLEQLKADVLAANLALPAHHLVTFTWGNVSAVDETRQWMVIKPS
                     GVEYDVMTADDMVVVEIASGKVVEGSKKPSSDTPTHLALYRRYAEIGGIVHTHSRHAT
                     IWSQAGLDLPAWGTTHADYFYGAIPCTRQMTAEEINGEYEYQTGEVIIETFEERGRSP
                     AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPAMQNELLDKH
                     YLRKHGANAYYGQ"
     gene            4442..4630
                     /locus_tag="IT892_004360"
                     /pseudo
     CDS             4442..4630
                     /locus_tag="IT892_004360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4652..5392)
                     /locus_tag="IT892_004361"
     CDS             complement(4652..5392)
                     /locus_tag="IT892_004361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MipA/OmpV family protein"
                     /protein_id="HAP3137486.1"
                     /translation="MLINRNIVALFSLPFMASATASELSIGAGAAYNESPYRGYNENT
                     KAIPLISYEGDTFYVRQITLGFILSQSEKNELSLTASWMPLEFDPTDNDDYAMQQLDK
                     RDSTAMAGVAWYHHERWGTVKASAAADVLDNSNGWVGELSVFHKMQIGRLSLTPALGV
                     LYYDENFSDYYYGISESESRRSGLASYSAQDAWVPYVSLTAKYPIGEHVVLMASAGYS
                     ELPEEITDSPMIDRNESFTFVTGVSWRF"
BASE COUNT         1287 a         1498 c         1508 g         1154 t
ORIGIN      
        1 gaaagcctca cttgaaggta aaggactgaa agtactggcc tactgggaaa acggctggcg
       61 cgatgtcacc aactcgcgcg caccggttaa aacccccgcc gacctgaaag ggctgaaaat
      121 ccgcaccaac aatagcccga tgaatatcgc cgcattcaaa gtctttggcg ctaacccgat
      181 cccgatgccg tttgccgaag tctataccgg gctggaaacc cgcactatcg acgctcagga
      241 acacccgatc aacgtcgtct ggtcagcaaa atttttcgaa gtgcagaagt tcctttctct
      301 gacgcaccac gcctattccc cgcttctggt ggtgatcaac aaagcgaagt ttgatggctt
      361 aagtccggag ttccagcagg cgctagtttc atctgcacaa gaagcgggta actatcagcg
      421 caaactggtt gctgaagatc agcaaaaaat catcgacggc atgaaagaag cgggcgtgga
      481 agtcatcacc gatctcgacc gcaaagcctt tagcgacgca ctggggaatc aggttcgcga
      541 catgtttgtt aaagatgtgc cgcagggagc tgatctgctg aaagccgtgg atgaggtgca
      601 ataaaccatg acgcaatact ggctggggtt agattgtggc ggtagctggc tgaaagccgg
      661 gctgtatgac cgcgaaggcc gggaggcagg cgtgcagcgc ctgccgctgt gcgcattaag
      721 cccgcagcca ggctgggcag agcgcgatat ggcagaactg tggcaatgct gcatggctgt
      781 cattcgcgcc ctgcttactc attctggtgt tagcggggaa caaattgtcg gtatcggcat
      841 ctccgcacag ggaaagggct tgtttttgct ggataaaaac gacaaaccgc tcgggaatgc
      901 tattttgtcc tcggaccgcc gggcgatgga aatcgttcgt cgctggcagg aagatggcat
      961 cccggaaaaa ctctacccgc tgacccgaca aaccttgtgg accgggcatc cggtgtcgct
     1021 gttacgctgg ctgaaagagc acgaaccaga acgctacgcg caaattggct gcgtgatgat
     1081 gacgcacgac tacctgcgct ggtgtttaac tggcgtcaaa ggctgtgaag agagcaatat
     1141 ttccgagtcc aacctctaca acatgagtct tggggaatat gacccgtgcc tcaccgactg
     1201 gctggggatc gctgaaatca atcacgccct gccgcctgtt gtcggatctg ccgaaatctg
     1261 cggggagatc accgctcaga cagccgccct gaccggtctg aaagcgggta cgcccgttgt
     1321 tggcggcctg tttgatgtgg tttccaccgc actctgcgcc gggatcgaag acgaatttac
     1381 cctcaatgcg gtgatgggga cctgggcggt gaccagcggc ataacccgcg gtttacgtga
     1441 cggtgaagcg catccgtatg tctatggtcg ctacgttaac gatggtgaat ttatcgttca
     1501 cgaagccagc cctacctctt ccggcaacct cgaatggttt accgcacagt ggggagaaat
     1561 ctcgtttgat gagatcaatc aggccgttgc cagcttgccg aaggctgggg gcgatctctt
     1621 tttcctgccg ttcctgtacg gcagcaacgc cggactcgag atgaccagtg gtttctacgg
     1681 gatgcaggcc attcacaccc gcgcgcacct gttgcaggcc atctatgaag gggtggtgtt
     1741 cagccatatg acccacctca accgaatgcg cgaacgtttt actgatgttc acaccctacg
     1801 cgtcactggc ggcccggcgc actccgatgt ctggatgcaa atgctggcgg acgtcagcgg
     1861 tctgcgtatc gagctgccgc aggtggaaga aaccggctgc tttggtgcgg cccttgccgc
     1921 ccgcgtcggc accggggttt atcacaactt cagcgaagcc caacgtgact tgcgacaccc
     1981 ggtgcgcacc ctgctgccag atatgaccgc ccatcagctt taccaaaaaa aatatcaacg
     2041 ttatcagcat ctcattgccg cacttcaggg ctttcacgcc cgcattaagg agcacacatt
     2101 atgagccgac cacttctgca actggccctc gaccactcat cacttgaagc cgcgcagcgc
     2161 gacgtgacgc tgttaaaaga cagcgtcgat atcgtcgaag cgggcaccat tctctgttta
     2221 aacgaagggc ttggcgcggt gaaagccttg cgcgaacagt gcccggacaa aatcatcgtt
     2281 gctgactgga aggtcgccga cgctggtgaa acgctcgcgc aacaggcgtt tggcgcaggc
     2341 gctaactgga tgaccatcat ctgcgccgcg ccgctcgcga cggtagaaaa aggccacgca
     2401 atggcacaac gctgcggggg tgaaattcag atagagctgt tcggtaactg gacgctggac
     2461 gacgcccgcg actggcatcg tattggcgtg cggcaggcca tttatcatcg cggtcgtgat
     2521 gcacaggcca gcgggcaaca gtggggcgaa gccgatctgg cacgcatgaa ggcgctttca
     2581 gatatcggcc ttgagctttc cattactggc gggattaccc ctgctgacct gccgctgttt
     2641 aaagatatcc gcgtgaaagc gtttattgcc gggcgggcac tggcaggcgc ggcaaatccg
     2701 gcgcaagtgg ctggcgattt ccatgcgcaa atcgacgcta tctggggagg tgcgcgtgcg
     2761 taatcatccg ttagggattt atgaaaaagc gctggcgaaa gatctctcct ggccggagcg
     2821 gctggtgctg gcaaaaagct gcggttttga ttttgtcgaa atgtcggtgg atgaaaccga
     2881 cgaacggctc tcacgtcttg actggagcgc cgcacaaagg acttcgctgg ttgccgcgat
     2941 gatcgaaaca ggtgttggga tcccgtcgat gtgcctgtcc gcacatcgtc gctttccctt
     3001 tggtagccgt gacgaggcag tgcgcgaacg ggcgcgggaa atcatgagta aagcgattcg
     3061 cctggcgcgc gatctcggca ttcgcaccat ccagctggca ggttatgacg tctattacga
     3121 agaccacgac gaaggcaccc ggcaacgttt tgctgaaggg ctggcgtggg cagtcgaaca
     3181 ggcggcggca tcacaagtaa tgctggcggt ggagattatg gataccgcgt ttatgaactc
     3241 catcagcaaa tggaaaaaat gggacgagat gctcgcctca ccgtggttca ccgtctaccc
     3301 ggacgtcggc aacctcagcg cctggggcaa tgatgttccc gccgaactga aactgggcat
     3361 tgaccgtatc gccgcgatcc acctgaaaga cacccagcca gtcaccgggc aaagtcccgg
     3421 acagttccgc gacgtgccgt ttggcgaagg ctgcgtcgat ttcgttggca tcttcaaaac
     3481 gctgcataaa ctgaactatc gcggttcttt cctgattgag atgtggaccg aaaaagccaa
     3541 agagccggtg ctggagatta ttcaggcgcg gcgttggatt gaagcgcgta tgcaggaggc
     3601 tggatttata tgttagagca actgaaagcc gacgtgctgg cggcgaatct ggcgcttccc
     3661 gctcaccatc tggtgacgtt cacctggggc aatgtcagcg cggtagacga aacgcggcaa
     3721 tggatggtaa tcaaaccttc cggcgtcgag tacgacgtga tgaccgccga cgatatggtg
     3781 gtggttgaga tagccagcgg taaggtggtg gaaggcagca aaaaaccctc ttccgataca
     3841 ccaacgcatc tggcgctcta ccgtcgctat gccgaaattg gcggtattgt gcatacccac
     3901 tcgcgccacg ccaccatctg gtcacaggcc gggctggatc tccccgcctg gggcaccacc
     3961 cacgccgatt atttttacgg tgccatcccc tgcacgcgac agatgaccgc agaggagatt
     4021 aacggcgaat atgaatatca gaccggcgaa gtgatcattg aaaccttcga agaacgtggc
     4081 aggagtccgg cacaaatccc ggcggtgctg gtgcattctc acggcccgtt cgcatggggt
     4141 aaaaacgccg ccgatgccgt gcataacgcc gtagtactcg aagaatgcgc ctatatgggt
     4201 ctattctcgc gccagcttgc gccgcagctc cctgcgatgc aaaacgaact gctggataag
     4261 cactacctgc gtaagcatgg ggccaatgcc tattacgggc agtaatccct cacgccgggg
     4321 cttcatcgcc ccggcactac gaattgatat gttccttgct gtaacgccgc ttccacgctg
     4381 ctggcgttaa accagtatgt ttctgaaaaa tctgccggaa atagccaacg tcattaaacc
     4441 gtattgcatg gagcaggccg acaacgtcga gtcactgcat aacctgttgc tgcccgccga
     4501 tgcgccattt acgacatttg aaggcaaggg attgttcagc cataagatcc tgattcagac
     4561 gccaggttcc cggtatgaac agagcaatcc agagcaacaa cctttgtggc attacgacgg
     4621 agcaccagcc gcaccgacat ctaccggtga attaaaaacg ccagctcacc ccggtgacaa
     4681 aggtaaaact ctcattacga tcaatcatcg ggctgtcggt aatctcttcc ggcagctcgc
     4741 tgtatcctgc gctcgccatc aatacgacgt gctctcctat cgggtatttt gccgtcaggc
     4801 tgacataggg cacccaggca tcctgcgcgg aataacttgc cagaccgcta cgacgggact
     4861 cactctctga aatgccatag taatagtcac tgaaattctc gtcataatag agaacgccca
     4921 gcgcaggtgt cagcgacaga cgacctatct gcattttgtg gaataccgat agctccccca
     4981 cccagccgtt gctgttatcc agaacgtccg cagctgcaga ggctttcacg gttccccaac
     5041 gctcgtggtg ataccaggca acccccgcca tagccgtact atcacgctta tcaagctgtt
     5101 gcatggcata atcgtcatta tcggtagggt caaattccag cggcatccag gatgcggtca
     5161 ggctaagttc atttttttca ctttgcgaca gaataaaacc taacgtgatc tgacgaacat
     5221 aaaaagtatc accttcataa ctaatcagcg gaattgcctt cgtattttca ttataaccgc
     5281 gataaggcga ttcattataa gccgcaccag caccaatgga taattcagaa gcagttgcgc
     5341 ttgccataaa aggcaacgaa aataacgcca caatattgcg attaattaac atgtccggta
     5401 ttccatttta aaataagata aaaaagagtc ggcataataa tgcttac
//
LOCUS       DACAOP010000178         5440 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.179, whole genome shotgun sequence.
ACCESSION   DACAOP010000178 DACAOP010000000
VERSION     DACAOP010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5440
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.179"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..425)
                     /locus_tag="IT892_004362"
     CDS             complement(<1..425)
                     /locus_tag="IT892_004362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137487.1"
                     /translation="MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPT
                     EHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKAAHVHEKPSTPPGNITALVIYLLSC
                     WRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRFDGPQLA"
     gene            599..1291
                     /locus_tag="IT892_004363"
     CDS             599..1291
                     /locus_tag="IT892_004363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HAP3137488.1"
                     /translation="MQSITPPLIAVIGSDGSGKSTVCEHLITVVEKYGAAERVHLGKQ
                     AGNVGRAVTKLPLMGKSLHKTIERNQVKTAKKLPGPVPALVITAFVARRLLRFRHMLA
                     CRRRGLIVLTDRYPQDQIPGAYDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKPDL
                     VIKLNVDLEVACARKPDHKRESLARKIAITPQLTFGGAQLVDIDANQPLEQVLVDAEK
                     AITDFMTARGYH"
     gene            complement(1340..2839)
                     /gene="pitB"
                     /locus_tag="IT892_004364"
     CDS             complement(1340..2839)
                     /gene="pitB"
                     /locus_tag="IT892_004364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitB"
                     /protein_id="HAP3137489.1"
                     /translation="MLNLFVGLDIYTGLLLLLALAFVLFYEAINGFHDTANAVAAVIY
                     TRAMQPQLAVVMAAFFNFFGVLLGGLSVAYAIVHMLPTDLLLNMGSTHGLAMVFSMLL
                     AAIIWNLGTWFFGLPASSSHTLIGAIIGIGLTNALLTGSSVMDALNLREVTKIFSSLI
                     VSPIVGLVIAGGLIFLLRRYWSGTKKRDRIHRIPEDRKKKKGKRKPPFWTRIALIVSA
                     AGVAFSHGANDGQKGIGLVMLVLVGIAPAGFVVNMNASGYEITRTRDAVTNFEHYLQQ
                     HPELPQKLIAMEPPLPAASTDGTQVTEFHCHPANTFDAIARVKTMLPGNMESYEPLSV
                     SQRSQLRRIMLCISDTSAKLAKLPGVSKEDQNLLKKLRSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVAMTIGEKIGKRGMTYAQGMAAQMTAAVSIGLASYIGMPVSTTHVL
                     SSAVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAIFLSGGLYWIALQLI"
     gene            complement(3131..4990)
                     /gene="gss"
                     /locus_tag="IT892_004365"
     CDS             complement(3131..4990)
                     /gene="gss"
                     /locus_tag="IT892_004365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutathionylspermidine
                     amidase/synthase"
                     /protein_id="HAP3137490.1"
                     /translation="MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVF
                     RSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQ
                     AFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQ
                     WTRELEMVVENGCYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLEN
                     KGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLH
                     ATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNAD
                     SASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEE
                     NYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQ
                     IREVSDREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLF
                     PHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKFAEQKNI
                     YQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVKK"
     gene            5195..>5440
                     /locus_tag="IT892_004366"
     CDS             5195..>5440
                     /locus_tag="IT892_004366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311901.2"
                     /note="YghU; B2989; one of eight putative glutathione
                     transferase proteins from E. coli; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HAP3137491.1"
                     /translation="MTDNTYQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHP
                     LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRI"
BASE COUNT         1419 a         1400 c         1283 g         1338 t
ORIGIN      
        1 gccaattgcg ggccatcaaa gcgaaacccc ggcacttcaa cctgcgggta gcggtcggtg
       61 atgagcagaa agccttgctg gcttttacac aacattttgc gaaacttgta cgcccgccag
      121 caggaaagca gatagataac cagtgcagta atattgccag gcggtgttga gggcttttcg
      181 tgcacatgtg ccgctttact tcgcagataa cgcccaaaag gtgcgccaat aacagggagc
      241 tgtgaaatcc attcgccaat tcgcccggac gattgcccga gataaatgtg ttctgttggc
      301 attcttgctg ccagttcatt taccaggctt gccgtgaggg tcgatttacc tgaaccatca
      361 catcctacaa tggcaataac acgcactggc gtggaattaa ttattgacat attacgttga
      421 ttcacgaaaa acccggcagt aaataatgta ttgaatatta cgtggtccgt gctcagaata
      481 tccgttcaac cttattgtga caatggttaa ttgtgacatt gacctgaatt acgctttcat
      541 aaaaacatat taaccaaata aatattttta atggatattt aaattaaagg atatattcat
      601 gcagtcaata acacctccat taattgccgt tattggtagc gatggttcag gcaagtcaac
      661 ggtgtgtgaa catcttatta ccgttgtcga aaaatatggt gctgccgaaa gagttcattt
      721 aggaaaacag gccggaaatg tcggtcgtgc agtgacaaaa ttaccgttga tgggaaaatc
      781 cttacataaa acaattgaac gaaatcaggt gaaaacagca aaaaaattgc ctggaccagt
      841 tccggcgctg gtaattacag cgtttgtcgc ccgtcgctta ctgcgctttc gtcatatgct
      901 tgcctgtcgt cgtcgcgggt taattgttct aaccgaccgt tatcctcagg accaaattcc
      961 tggcgcttac gatggtacgg tgttcccacc taacgttgaa ggtggtcgtt ttgtctcatg
     1021 gctggcaagc caggaacgta aagcgtttca ctggatggcg agccataagc ctgatctggt
     1081 catcaaactc aatgttgacc ttgaagttgc ctgtgcacgt aaacccgacc ataaacggga
     1141 atcgctggcg aggaagattg ccataacgcc acagttaacc tttggtggtg cacaactggt
     1201 tgatatcgat gccaatcagc cactggaaca ggtgttggtt gatgcagaaa aagcgattac
     1261 ggattttatg accgcgcgtg gttatcacta gtcaaaaatg gaaatgcccg atcgccagga
     1321 ccgggcattt tcaggaaggt taaatcaact gcaatgctat ccagtacagc ccaccagaaa
     1381 gaaaaattgc cgccggtaaa gtaaataccc acgccatcag gatgctggtt accgttttac
     1441 gctgtaaccc accgccgtcc accaccatcg tccctgcaac tgcagacgag aggacgtgtg
     1501 ttgtggagac gggcatccca atataactgg caagaccgat agacactgcc gccgtcattt
     1561 gtgccgccat gccttgcgca tacgtcatgc cgcgcttacc aatcttctca ccgatggtca
     1621 tcgctacacg acgccagcca atcatggtgc caatgccgag cgccagtgct accgccatga
     1681 tgatccacac cggagcgtac tcaatggtgc ttaacatatc gctgcgaagt tttttcagca
     1741 ggttctggtc ttctttactg acgcctggca gtttcgctag cttcgcggag gtatcagaga
     1801 tgcacagcat aatgcggcgc agctggctgc gctgactcac gcttaacggc tcgtaacttt
     1861 ccatattgcc tggcagcatc gttttaacgc gcgcaatagc atcaaaggta tttgccggat
     1921 gacagtgaaa ctctgttact tgcgtgccat cagtcgatgc tgcaggcaat ggaggttcca
     1981 tcgcaatcaa cttctgcggc agttcaggat gctgttgcag gtagtgttcg aagttggtaa
     2041 cggcatcgcg ggtacgggta atttcatagc cggacgcatt catattgacg acgaagccag
     2101 caggggcaat ccccaccagt accagcatta ccaggccgat ccctttttgt ccgtcgttcg
     2161 cgccgtgcga aaacgccacg cccgcagcgg aaacaatcag cgcaatacgc gtccagaatg
     2221 gcggtttacg tttgcctttt ttctttttgc gatcttccgg aatgcggtga atacggtcac
     2281 gctttttcgt cccgctccag tagcgtcgca gcaggaatat caggcctccc gcaatgacca
     2341 ggccgacgat aggggaaaca atcagcgagg agaaaatttt ggtcacttca cgcaggttta
     2401 acgcatccat caccgatgag ccggttaaca gcgcgttggt taaaccgatg ccgataatcg
     2461 caccaatcaa ggtgtgcgaa ctggaggccg gtaaaccgaa gaaccacgtt cccaggttcc
     2521 agataatcgc cgccagcagc atggaaaaga ccatcgccag gccgtgggtt gaccccatat
     2581 tcagcaacaa atcggttggc aacatatgga caatggcata ggcaacgcta agtccgccca
     2641 ataacacgcc aaaaaagtta aaaaatgccg ccatcaccac agcaagttgt ggttgcatgg
     2701 cacgagtata aataacggct gccaccgcat tcgccgtgtc atgaaaacca ttgattgctt
     2761 cgtagaacaa cacaaatgcc agagcaagca ataacaaaag ccctgtgtat atatcaaggc
     2821 caacaaataa atttagcata tattagatta cgccattttg aatttacgaa cggacgcatt
     2881 atcagtgact ttaacggcat gggcaaagtg aaatatcatt ttttaacgat aaaaagagtg
     2941 ttatttcttg tgtatcagac aataagcatt cattcaaaac ctttagaaat aatcaaaaca
     3001 caggtattcc actggttaat atattcacat atgaaatgaa taaatattgg aatatataaa
     3061 tattgaatat tttgattaat ccccgtactg attattcttc ataatcagta cggggttgct
     3121 acaacatgta ttactttttc accacaatta acggttcaat atcactctct tttttgatga
     3181 ccagtgattc atcaccgcgc aaacacgtcc caccgtagtt gccgccaacg gtgaaggtac
     3241 atacctgaat gtatttaccg tccactttcg gcaaacacca cagttgctga tagatgtttt
     3301 tctgctcggc aaatttaccg ctggttttgt ccagcacctc ttcatgatgg ctgacgaggt
     3361 cgatattgct gccacagcga ccggcgatcg gtttcactgc gtaacctgtt ttcaccagtt
     3421 catcattaac agtgaaatcg gtatccagca ggtaacgatg gtgcgggaac agcgaccaga
     3481 ggatcggcag aatcgctttg ttgccgggga tcaccgtcca cagcggctca aagaccagca
     3541 cttccgggcg cagcaatacg tcgataagac gcacttcgtt ttgcggatga ccggtacgga
     3601 ttggcaccgc agcaaactca cggtcgctaa cttcacgaat ctgatcaaac gcggtttccc
     3661 acgcccaggt tttccacacg cagttaacca gtcgcccttc cccatcaatc agttgcccgg
     3721 cagcatccca gcccagttca tccaatccac gcaagatacg cgtttcaaag cccgcctggt
     3781 gcagcgcctg ctccataaac tgcgcgtgat agttttcctc gatatctttg tcctgcatga
     3841 tatggacaaa cggacgtgca cgactgtgtt tccaggcacc agccaattcg ttaatcagcc
     3901 cttccgccgg attgaagccg ttgcctttat agccctgctc cgcccaacgt tcgaggatca
     3961 agcccgcttc ggtatgacag gaggcggagt cggcgttgta ctcgtaaacc ttcaggccac
     4021 gctcatccat gcagaaatcc atacgaccag tgatcatatg gtgacggcga cgctgccagg
     4081 agagacgcaa acgtggccag aggattttcg ggatgtcgaa cagcgccagc aggttgtcat
     4141 ctttcagcac cttgtcggtt gcgtgaagat acatcaggtg cagctcgttg gtggctttaa
     4201 ttagctcctg ctcggcactc tcggtaatgg tgtagtaatg ataaggatcc tgattgatca
     4261 cctgaccgtt ggcctgcaca taggcgtttt gcagcggatc tttttcatcc agccatttac
     4321 cgtcaaactg gcctttgttt tccaggcgcg ctccgctgat tttcagcagc tcgcctgcaa
     4381 tttccggctg cggtaagctg tattcagtat cttccgtctg gatcatccag cccagaatgg
     4441 tggtgtcatc aaaagtgtct ttcagggtat agcagccgtt ttcgaccacc atctccagct
     4501 cgcgcgtcca ctgttgccct tgcggcaacg gggaatgaat cacgttctgt tccgcaatac
     4561 ggactttgtt gccatgcaat tgggtaatga tggcgacatg gccagtgtct ttaaattcac
     4621 cgcctttatc ccagataaga agcgcacccg cgaccggcgc acgcggcgag ccgttaggaa
     4681 atgcctgcaa tggcaggatg ttgtcattaa ccacttctcg caggaagcgc agcgagaaaa
     4741 tctcccacgc catacccacg tcagtaaaga ccacaccgta attcagaaag agaaaacggc
     4801 gagcaaattc aacgcattgc cacttgtggc ccatatattc gtcgtcgata tagctacgga
     4861 atacggcgtc atcttcgtat tcctgcggat cgagagaact gtaatctgaa gagtagattg
     4921 ctaccccacc tggggcgtag cccaataatg tcccgaacgg ggcatcctgg ctggtcgttc
     4981 ctttgctcat cactttacct ttaacaatac aacctaagca gttggcgtaa ttgttgtgct
     5041 ctgattacct gctcagcgac attaaccgga cagaggtcag actaatcata cacctcatcg
     5101 cagcggctgg cgcaaagggt taaaaaattc acattctgta cagcaagtga cctgctacac
     5161 tgcttcaaca ctaccactca gaaggcaact cactatgaca gacaatactt atcagcccgc
     5221 gaaagtctgg acgtgggata aatccgctgg cggcgcgttc gccaatatca atcgcccggt
     5281 ttctggtccg acgcatgaaa aaacgctgcc cgttggcaaa cacccattgc aactttattc
     5341 gctgggaacg ccgaacggtc agaaagtaac gattatgctt gaggagctgc tggcgctggg
     5401 cgttactggt gcagagtacg acgcctggct gattcgtatt
//
LOCUS       DACAOP010000179         5428 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.180, whole genome shotgun sequence.
ACCESSION   DACAOP010000179 DACAOP010000000
VERSION     DACAOP010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5428
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.180"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(49..507)
                     /locus_tag="IT892_004367"
     CDS             complement(49..507)
                     /locus_tag="IT892_004367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF986 domain-containing protein"
                     /protein_id="HAP3137492.1"
                     /translation="MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGR
                     IDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFA
                     NVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSTQ"
     gene            complement(562..1413)
                     /locus_tag="IT892_004368"
     CDS             complement(562..1413)
                     /locus_tag="IT892_004368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020804907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IID"
                     /protein_id="HAP3137493.1"
                     /translation="MVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCF
                     SMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDG
                     AINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
                     TRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSR
                     ITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGY
                     ACGLLGL"
     gene            complement(1426..2226)
                     /locus_tag="IT892_004369"
     CDS             complement(1426..2226)
                     /locus_tag="IT892_004369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAP3137494.1"
                     /translation="MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLG
                     DMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPL
                     AAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVAL
                     SVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAA
                     FTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD"
     gene            complement(2289..3260)
                     /gene="manX"
                     /locus_tag="IT892_004370"
     CDS             complement(2289..3260)
                     /gene="manX"
                     /locus_tag="IT892_004370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAP3137495.1"
                     /translation="MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAET
                     LIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIVVDKEHYEVIAGVNIPMLVETL
                     MARDDDPSFDELVALAVETGREGVKALKAKPVEKAAPAPAAAAPKAAPTPAKPMGPND
                     YMVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTA
                     HVVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERLVEGGVKITSVNVGGMAFRQGKTQ
                     VNNAVSVDEKDIEAFKKLNARGIELEVRKVSTDPKLKMMDLISKIDK"
     gene            3723..5279
                     /gene="yoaE"
                     /locus_tag="IT892_004371"
     CDS             3723..5279
                     /gene="yoaE"
                     /locus_tag="IT892_004371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family cation transport protein YoaE"
                     /protein_id="HAP3137496.1"
                     /translation="MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRD
                     KARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMDFSFSGRDLIMLFGGIFLLFKAT
                     TELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
                     VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAI
                     GFSIIIEVFNQIARRNFIRHQSTLPLRARTADAILRLMDGKRQANVQHDADNPMPMPI
                     PEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEIREQLLSSPHSLF
                     PVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRAR
                     GSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIITDGDGWLVKGGTDLHALQ
                     QALDVEHLADDDDIATVAGLVISANGHIPRVGDVIDVGPLHITIIEANDYRVDLVRIV
                     KEQPAHDEDE"
     gene            complement(5283..5428)
                     /locus_tag="IT892_004372"
                     /pseudo
     CDS             complement(5283..5428)
                     /locus_tag="IT892_004372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416329.4"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rtn protein"
BASE COUNT         1335 a         1361 c         1376 g         1356 t
ORIGIN      
        1 tctgattatt aaaaatacac taagcatagc tttggctaaa ttcataactt attgagttga
       61 aacgagaagc ttataaattt tttccagatc gtcgatattt cgaacgcgga ttaacagccg
      121 acgctgttct aattgcatca ccaacacgcc atcttccgac aagttcatcg ctttgattcg
      181 gctatattca atccagacat tggcgaagaa aaaacctttt tgtttaaaga tgatcttcgg
      241 aacgcggatc cagaatatat aaaaacccat cagagccagt gcgcttaata accatgtcgt
      301 tattaacgca ccatgattcg tgacgttgtt atagataaga atgacaatca atccgacgaa
      361 gataacgcta tcgatgcgac cacgccggag caaaggaatt gccagcaggg tggggccgtt
      421 acggcggggc atgatgaact gatcgtagat cgcgaaggcc aggagtgcgg cgatgaaaag
      481 aatcagtacc aggtccgtga ttgtcattaa tcctccagat aaaaaaacgg ggccaaaagg
      541 ccccggtagt gtacaacagt cttacagtcc cagcaggccg caagcgtaac cagcgatacc
      601 gatgacgaag aagccaacga tgatccacag cgggttaact tttttgcgca gtagccacat
      661 acaagcaaag gtcagcagca gtggtaccag gcctggcatt aactggtcca gaatagtctg
      721 gacagtagta acgtgttctt tgcccgtctg gtcagtaatg cgagagacaa ccagcgggat
      781 gttgacatgt gtccacttgt taaccaatgc ccccatgaca aacaggccga ggatagacgc
      841 cccttccgtc agtttttgca ggaagccacc acccatatct ttaacgatat cgataccttt
      901 ggagtaacca tacgctacgc cgtagtaacg ggttgccaga cgcaccaggt taaacaggat
      961 gaagaacagc agcggaccta acaggctgcc gctcatcgcg ataccggcac ccagtgctgc
     1021 aaataccgga cgtacggttc cccagaagat cgggtcgcct acaccagcca gtggccccat
     1081 caaaccgact ttgataccgt tgatagcacc gtcgtcgatc tctgcgccat tagcacgctg
     1141 ttcttccagc gccagggtta cgccgagaat cggcgcagcc acgaacggct gggtgttaaa
     1201 gaactccagg tgacggcgaa tagcttgttt acgagcttcg ttgttctcag ggtagaggcg
     1261 acgaattgcc ggtaccatag agaagcagaa acccagtgcc tgcatacgtt cgaagttcca
     1321 tgaaccctgg aagaggttag aacgcaggaa gacgccacga atatcacttt gagtgagttt
     1381 tttctcggtg gtagtttgag ttgtatcaac catttcgctc acctgttagt ccagttcgtt
     1441 atcgagatcg ttgttaccag ctgcctgagc aggcgcaccg gctacgcggt tgtatttcgg
     1501 gctaagttgg atgtagagca ctgccataac agtaccaatc acacccagag caaccaggtt
     1561 aaagttggtg aatgctgcgg ttacgaagcc gaggtagaag aacggcatca ggtagccagc
     1621 acgcatcatg ttgataacca tcgcataacc aaccaccacg atcatgccac cggcgatatt
     1681 cagaccattg gtcaccactt ccggaatcgc attcagcatg ttctgtactt cgctggtacc
     1741 aacagacagc gcaacgatga cggccggaat agccacacgc attgcttgca ggaacagaga
     1801 agaaacgtgg atccaggaaa tcgctgtcag gttgccgtta tcagcagcct tatccgcagc
     1861 gtgctggaaa gcaacggtaa tagtacgaac gatgatggtc agtacctggc ccgcagcggc
     1921 cagagggatt gccagtgcga tacctgcacc aatgctctga tgacctgcga taaccagaat
     1981 ggtagaaatg atagaagcca gagcggcgtc aggcgcaact gcagcaccga tgttcatcca
     2041 gcccagcgcg atcatttcca gcgtaccacc gataataata ccggttttca tatccccaag
     2101 aacgataccc accagggtac acgcgattag cggacggtga aactgaaatt catcgaggat
     2161 tgatcccata cctgcgatac aggctacgat aaataccagc acaatttgaa gagtggtaat
     2221 ctccattgta cttctcctgt ttacgtaaga cttaagtgtg aaaactgagt gataatcaac
     2281 acaatacgtt acttatcgat tttgctgatc agatccatca ttttcagttt cggatcggtg
     2341 gaaaccttac ggacttccag ctcaataccg cgcgcattca gtttcttgaa cgcctcgata
     2401 tctttttcat caaccgaaac cgcgttattc acctgggttt taccctgacg gaatgccata
     2461 ccaccgacgt taacagaggt gattttcacg ccgccttcaa cgagacgctc tacatctgtt
     2521 gggttggtaa ataacagcat tacgcgttcg ccagcatatt tcgggttgtt gtagacgcga
     2581 atcattttgg caacatcaac tacgtgtgct gttacgcccg gaggtgcaac ctgggtgagc
     2641 agtgtcttac gaacggtatc cgcagccact tcatcactaa caacaataat acgggagaca
     2701 ttggtttctt tggtccagcg ggtggcgacc tgaccgtgaa tcagacggtc gtcgatacgc
     2761 gcaaggccaa taaccatgta gtcgtttggc cccattggtt ttgccggagt tggagccgct
     2821 tttggtgctg cggcagcggg tgctggcgcg gctttttcaa ccggtttggc tttcagtgct
     2881 ttcacgcctt cacggcctgt ttctactgcc agtgccacca gttcatcaaa gcttgggtca
     2941 tcatcacggg ccattaacgt ttccacgagc attggaatgt taacgcctgc aatgacttca
     3001 taatgctctt tgtcgacgac aatgcggctg gcagcattga acgggctgcc tccccatgta
     3061 tcaacgagaa acagcacgcc tttagtggtg tcgagttttg ccaactgagc gttgtacttt
     3121 tcaatcagcg tttcggcatt ttcacctgga acgaaatcga tccagccgac gttttcctgc
     3181 tcgcctaaca gcatttctgc cgttttaagc aactgctctg cagcccaacc atgtgtgcct
     3241 ataacaatag caatggtcac ttgctacctc ctttattatc gttaacacct caacgtgcca
     3301 gatgtatttt tgaatcgtcg tccacaatcg aatcgattca gataagggct acaaccaaaa
     3361 acccctgcgt ttcgcgattt attttagata tcgaaaaaat tattttatgt gatgaagatc
     3421 cgtaatttaa ctttcgatta gcagaaattt cgaaaggtaa aatatccttg tcacattcgt
     3481 ttgcaaagga aggtaaatct ttgccaaatc agaggcgtct ctgatatgtt taactcccgt
     3541 ttaacaacca tggagtatag ggcagtagcc cgcagtatgg atcgtcaccg acgtcatttc
     3601 agcatcaggc cttttaacgc ctgcctttct ggcactctat gccgcacctt tcgtttgcat
     3661 tttgtcgtta cgcctgcatt atttctggcg tcgaatagct attccttaag caggagcttg
     3721 tcatggaatt cttaatggac ccctcaattt gggcggggct actcacgctt gttgttctcg
     3781 aaattgtgct gggtatcgat aacctggtct tcatcgccat tcttgctgac aaactgccgc
     3841 caaaacaacg cgataaagcg cgtttgctgg ggttatcact ggcgctgatt atgcgtctgg
     3901 ggctgctgtc gctgatttca tggatggtca cgctgaccaa accgctattt accgtcatgg
     3961 atttctcctt ctccggacgc gacctgatta tgttgttcgg ggggatattc ttgctgttca
     4021 aagcaacaac cgaactgcat gaacggctgg aaaaccgcga tcatgattcc ggccacggta
     4081 aaggctacgc cagtttctgg gtggtcgtca cacagattgt catccttgac gccgtcttct
     4141 cgttggatgc ggtaattact gcagtaggga tggttaacca tctgccggtg atgatggcgg
     4201 cggtagtgat tgcgatggcg gttatgttgc tggcatccaa accgctgacg cgattcgtta
     4261 accagcaccc cacggtggtg gtgctctgtc tgagcttcct gttaatgatt ggtctgagtc
     4321 tggtggcaga aggtttcggt ttccacattc cgaaaggtta cctgtatgcc gcgattggct
     4381 tctcgatcat catcgaagtg tttaaccaga ttgcgcgtcg caactttatt cgccaccagt
     4441 cgactttgcc gctgcgagcg cgtactgccg atgccatcct gcgtttgatg gacgggaaac
     4501 gtcaggccaa tgttcagcac gatgccgata acccgatgcc gatgccgatc ccggaaggtg
     4561 catttgccga agaagaacgt tacatgatta acggcgtact gacgctggcg tcgcgttctc
     4621 tgcgcgggat catgacgccg cgcggtgaaa taagctgggt tgacgctaat ctcggggtcg
     4681 atgaaatccg cgagcaactg ctctcttcac cgcacagtct gttcccggta tgtcgcggtg
     4741 aactggatga aatcatcggt attgtacgtg ctaaagaact gctggtggcg ctggaagagg
     4801 gcgttgatgt ggcggcgatt gcttcggcgt ctccggcgat tatcgtcccg gaaaccctcg
     4861 atccgatcaa cctgttgggc gtgctgcgtc gtgctcgcgg gagctttgtt atcgtgacca
     4921 acgagtttgg tgtggtacaa ggtctggtca cgccgctgga tgtgctggaa gccattgcgg
     4981 gtgaattccc ggacgctgac gaaacgccgg aaatcattac tgatggtgac ggctggctgg
     5041 taaaaggcgg tacagatttg catgccttgc agcaggcgct tgatgttgag caccttgccg
     5101 atgacgatga tatcgcgacg gtcgcgggcc tcgtgatctc ggcaaatggt cacattcccc
     5161 gtgtgggcga tgtgattgat gtagggccac tgcatatcac catcattgaa gccaatgatt
     5221 atcgtgttga tctggttcgc attgttaaag agcaaccggc gcacgatgaa gatgagtaag
     5281 cgttaacgta acggcataat gggcgtgata tgtccattat gccgggcggc ggttggctgc
     5341 ccgccagcca tttgggaaaa tcacgtagcg gcatcggctg tgcgtacaaa tacccttgca
     5401 aaatatgcac gccatgacgg cgcaaata
//
LOCUS       DACAOP010000180         5373 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.181, whole genome shotgun sequence.
ACCESSION   DACAOP010000180 DACAOP010000000
VERSION     DACAOP010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5373
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.181"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..207
                     /locus_tag="IT892_004373"
     CDS             <1..207
                     /locus_tag="IT892_004373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopN family type III secretion system gatekeeper
                     subunit"
                     /protein_id="HAP3137497.1"
                     /translation="DKTLLLKAIYSGCTNLPFSLFINNEQLLEIRECCKQAIKVTFAA
                     ELFDTQNSNKKQNKKPWKKVMFNV"
     gene            200..2260
                     /locus_tag="IT892_004374"
     CDS             200..2260
                     /locus_tag="IT892_004374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscV/YscV/HrcV family type III secretion system
                     export apparatus protein"
                     /protein_id="HAP3137498.1"
                     /translation="MFNKVLIGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLN
                     LTLAILVFLGSFYVDRILSFSSFPSILLITTLFRLALAISTSRLILLEADAGEIITSF
                     GEFVIGDSLVVGFVIFSIVTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLR
                     AGIIDADLAKERRSVLERESQLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQ
                     NGMDFSTALTVYTILTVGDGLVSQIPALLIAISAGFIVTRVNGDSDNMGQNIMSQLLS
                     NSFVIIVTCVLALSIGLLPGFPLLVFLCLAVILGIYFYFKFKKKGVEETVVEGDITVG
                     LEPYNQDDDISLGIINKLDQVITETVPLVLIMNSVQAKKYTEINLADRIRSQFFIEYG
                     IRIPGIVIREGEGLNDEDVILMLNEVRASQFKIYHDLVLLVEYSDEVVSTLIKKPIIV
                     NSNGEQYYWVTKSDAQKLTKIGCYTRTAMDEMYNHLSVCLAHNINEYFGIQETKYILD
                     QLEMKYPDLLKEILRYITVQRISEVIQRLIQERISVRNMRLVMEALALWSPREKDIIT
                     LVEHVRGALGRYICHKFSYSGEIKAIVISPEIEDRIRDGVRPTAGGTFLNLDASEAEM
                     ILDNFKLALSGINIPIKDIILLGSVDIRRFIKKLIESSYRDLEVLSYGELTENVPVNI
                     LKTI"
     gene            2292..3584
                     /locus_tag="IT892_004375"
     CDS             2292..3584
                     /locus_tag="IT892_004375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311757.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliI/YscN family ATPase"
                     /protein_id="HAP3137499.1"
                     /translation="MKKLKLLNKYSYLHSINGSLIEAELDDVSVGEVCEIYASWQANE
                     RIARAQVVGFRNGKTLLNLIGSSVGLTRTAVLKPTGEQLTIQISDAFLGSVLNASGQI
                     MERFVPDTPGDRGNLRLIDELPPSYQERRVINTPLETRIRVIDGVLTCGIGQRVGIFA
                     SAGCGKTVLMHMLVNNTEADVFVIGLIGERGREVTECAESLKKSVNAAKCVLVYATSD
                     FSSVDRCNAALMATTVAEYFRDRGKRVVLFIDSMTRYARALRDMKLAAGEPPARRGYP
                     ASVFDSLPRLLERPGPTLKGSITAFYTVLLEGEDESDPLGDEIRSILDGHIYLSRKLA
                     GQGHYPAIDVLKSVSRVFGQVTDEKHRDNAARVRKILTTLEDLQVFIDLGEYRAGQNA
                     ENDFAMNARPKLTNWLKQSVNEKMPMSETLKELERIVK"
     gene            3574..4032
                     /locus_tag="IT892_004376"
     CDS             3574..4032
                     /locus_tag="IT892_004376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion protein"
                     /protein_id="HAP3137500.1"
                     /translation="MLSKVNRLIRRTAQSLAACEASLQKLNAEKEKLAEKERLYDMQL
                     KNLQSLLDMKELLGEVVFRQDIFYSLRKVAVIQQQIAEINLEKQKIAERRKILNKEIV
                     QQQAQRKHWWLKGEKYDRLKKRIKKQLLNQMLYQDELEQEEKYNGRSQEN"
     gene            4010..4885
                     /locus_tag="IT892_004377"
     CDS             4010..4885
                     /locus_tag="IT892_004377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion protein"
                     /protein_id="HAP3137501.1"
                     /translation="MDEVKKIEHCKILNTDTPDNSASDLDSFLKKNKKNKEMSEIVAG
                     TILQLLRQTQDSQFSTLGKKNGHMESIDNKSSLQVDRNPSLSLQTNGTEKFSTKKILN
                     MTSRDQGNDSEPSNKTIQFKEKIHNGIHTEYITDQKHSNNKDREKKYRDGDKINGPQA
                     HSLDITNERRFADNRTMFTQHIEKQRNVHTLNQNDINNSANNANVRENELTYQFQRWG
                     QNHTVRILESSEGIRLKPSDTLVSDRLHEAQHNDVTAQRWVLTEQDERQGQRHQPHDE
                     QENEGKFENNQKDES"
     gene            4845..5373
                     /locus_tag="IT892_004378"
                     /pseudo
     CDS             4845..5373
                     /locus_tag="IT892_004378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311753.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YscQ/HrcQ family type III secretion apparatus
                     protein"
BASE COUNT         1741 a          913 c         1185 g         1534 t
ORIGIN      
        1 gacaaaacgt tactcctgaa ggcgatttac agcggatgta caaatcttcc attttcactt
       61 tttattaata atgaacaatt attagagatt agggagtgtt gtaaacaggc aataaaagta
      121 acatttgcag cagagctctt tgatacacaa aacagtaata aaaaacaaaa taaaaaacca
      181 tggaagaagg taatgttcaa tgtttaacaa agttttgata gggttaagga gtcatccaga
      241 attaataatt cttggattaa tggtgatgat tatcgccatg ctcataattc cattgcccac
      301 ctacttaatc gattttttga ttgggctgaa cttaacattg gcaatacttg tgtttttagg
      361 atcattctat gttgatagga tcttaagttt ttcttcattc ccatcaattc ttctcatcac
      421 aacgttattt cgtttggcgc tggcgatcag taccagccga cttatacttc ttgaggcgga
      481 cgccggagaa attataacga gttttggtga attcgttatt ggagatagcc tggtagttgg
      541 ttttgttatt ttctccattg ttactattgt tcagtttatc gtgattacta aaggttcgga
      601 acgtgtggct gaagttgctg cccgcttttc gcttgacggt atgccaggta aacaaatgag
      661 tattgacgcc gatctacgcg ccgggatcat tgatgcagat ttagcaaaag aacgtcgtag
      721 cgtattagaa cgagagagtc agctgtatgg ttcctttgat ggtgcgatga aatttatcaa
      781 aggtgatgct attgcaaaca ttattattat ctttgttaat attatcggtg ggctatcagt
      841 aggagtaggc caaaatggaa tggatttctc gacagcgttg accgtctaca caattcttac
      901 cgtcggtgat ggtcttgttt cacaaattcc agctttatta attgctatta gtgcagggtt
      961 tatcgtaacg cgcgtgaatg gcgatagtga taatatgggg caaaatataa tgtcccagtt
     1021 attaagtaat tcttttgtca ttattgtgac atgtgtcctc gcgctaagta ttgggttgct
     1081 tccaggtttt ccccttcttg tgtttttatg tttggcagta atcttaggaa tttattttta
     1141 ctttaaattc aaaaagaaag gggttgaaga aacggttgtt gagggagata tcaccgttgg
     1201 gttggaaccc tataatcagg atgatgatat ttcattaggt attattaata aacttgatca
     1261 ggttattacc gaaacggtac ccttggtttt gattatgaat agtgtacagg ctaaaaaata
     1321 cactgaaatc aatcttgctg ataggattcg tagtcagttt tttattgagt atggtatccg
     1381 tattcccggt attgtcattc gcgaggggga aggccttaat gatgaagatg tcatattaat
     1441 gctaaatgaa gtcagagcct cgcaatttaa aatttatcat gatctcgtct tgttggttga
     1501 atattcagat gaagtggttt cgactttgat caagaaacct atcatcgtaa atagtaatgg
     1561 tgaacaatat tattgggtta caaaaagtga tgcccaaaaa ttaacaaaaa ttggctgtta
     1621 tactcgcacg gccatggatg aaatgtacaa tcatttatct gtatgtctgg cgcataatat
     1681 taatgagtat tttggtatac aagaaaccaa atatattctt gatcaattag agatgaagta
     1741 tcctgatcta ttaaaagaaa tattaagata tataaccgtg cagcgcattt cagaggtaat
     1801 tcagcgtctg atccaggagc gaatttcagt gcgcaatatg cgtttagtta tggaggcttt
     1861 agcattatgg agcccacggg agaaagatat aattacactc gtcgagcatg tacgaggtgc
     1921 attaggtcgc tacatttgcc ataagttttc atattctgga gaaattaaag caattgtgat
     1981 ttcgcctgaa atagaggaca gaatcagaga tggtgtcagg cctaccgctg gcggtacttt
     2041 tcttaatctc gatgcatccg aagctgagat gattctggat aattttaaac tggctctttc
     2101 tggaatcaat attcctatta aagacattat tttactggga tctgtggata ttcgtcgttt
     2161 tatcaaaaaa cttattgaat ctagttatcg agacctcgaa gtactttcgt acggggaact
     2221 aacggaaaat gttcccgtta atattctgaa aactatttag gataatgtct tgcgatatgg
     2281 agcatgctgg tatgaaaaaa ttaaaactat taaataaata cagctactta catagcataa
     2341 acggctcgct gattgaagca gagcttgacg acgtttcagt gggcgaagta tgcgaaattt
     2401 atgcgagctg gcaagcaaat gaacgtatag ccagggctca ggtcgttggc tttcgcaatg
     2461 gaaagacatt attaaacctt ataggcagct ctgtggggct tacacgtact gcagttttga
     2521 aaccaacggg agagcagtta accatacaga tcagtgatgc ctttcttggt tcagttttga
     2581 atgcttctgg tcaaattatg gaaaggtttg tcccggacac tccaggcgat aggggaaatt
     2641 tacgcctgat tgatgaactg ccaccgtcgt atcaggagcg tcgagttatt aatacaccac
     2701 tagagacacg gataagagtc attgatggcg tactgacatg tggcattggt caacgtgttg
     2761 ggatttttgc atcagctggc tgtggcaaaa cggttttaat gcatatgctt gtaaacaaca
     2821 ctgaagctga tgtgtttgtt attggcttga ttggcgaacg tggaagggaa gttacggaat
     2881 gcgcggaatc gctgaaaaaa tcagtaaatg cagcaaaatg tgttttggtt tatgccacct
     2941 ctgatttttc gtcagtagat cggtgtaatg ccgccctgat ggcgacaacc gtggcagagt
     3001 attttagaga tcgaggaaag agagttgtac tttttatcga ctcaatgacg cggtatgcac
     3061 gagcactacg tgatatgaaa ctggcagcgg gtgaaccacc tgccagacgt ggttatcctg
     3121 cttctgtttt tgacagtttg cctcgcttac tggagaggcc gggaccaaca ctaaaaggaa
     3181 gtattactgc gttttatacc gtattactgg agggggagga tgaatcagac ccactgggtg
     3241 atgaaattcg ctcaatcctt gatggccata tctatctaag tcgcaaactc gctgggcaag
     3301 gtcattatcc ggcaatagat gttctaaaaa gtgtgagtcg agtatttggt caggtcactg
     3361 atgaaaaaca cagagataat gctgcacggg taaggaagat cctcacaact ttggaagatc
     3421 tacaggtgtt tattgattta ggggaatatc gcgctgggca aaatgctgaa aatgattttg
     3481 ctatgaatgc ccggcctaaa ctcacaaatt ggttaaaaca gtcagttaat gaaaaaatgc
     3541 caatgagtga aacgctaaaa gagcttgaac gaattgttaa gtaaagttaa tcgacttatc
     3601 agaagaacag cgcagagcct ggctgcatgt gaagcatcat tacaaaagtt aaatgcagaa
     3661 aaagaaaagt tagccgaaaa ggaacgcctg tatgatatgc aacttaaaaa cctacagtca
     3721 ctgttagata tgaaagagtt actcggcgaa gttgtatttc gacaggatat attttactcg
     3781 ttacgtaaag ttgcagtcat tcagcagcag atcgctgaga taaatcttga aaagcaaaaa
     3841 atagcagagc ggcgaaaaat acttaacaag gaaatagttc aacagcaagc acaaagaaaa
     3901 cactggtggc taaaaggaga aaagtacgat cgactaaaga agcgcatcaa aaaacaactt
     3961 ttaaatcaga tgctttatca agacgagctt gaacaggagg agaaatataa tggacgaagt
     4021 caagaaaatt gaacactgta aaattttaaa cacagacaca cccgataatt ctgcttcaga
     4081 tttagacagt ttcttaaaga aaaacaaaaa aaataaagaa atgagtgaga ttgtcgctgg
     4141 aaccattctc cagttattac gtcagactca ggatagccaa ttttctacgt tggggaaaaa
     4201 aaatgggcac atggagtcta ttgacaacaa atcatctctc caggttgaca ggaatccatc
     4261 tctttctttg caaacaaatg gaacagagaa attttctaca aagaaaattc tcaatatgac
     4321 ttcacgagat caggggaatg attctgaacc atctaataaa acgatacaat ttaaggaaaa
     4381 aatccataat ggtatccata cagaatacat cacagatcaa aaacacagta ataataaaga
     4441 tcgtgaaaaa aaataccgcg atggagacaa aataaatgga ccgcaggccc attcattaga
     4501 cattactaac gaaagaaggt ttgctgataa cagaaccatg tttactcaac atatcgaaaa
     4561 gcaaaggaat gttcatacgc tcaatcagaa tgatataaat aattctgcta ataatgccaa
     4621 tgtgcgcgaa aatgaattga catatcagtt tcagcgttgg ggacaaaatc atacagtccg
     4681 gattctggaa agtagtgaag ggatacgact aaaaccatca gacacacttg tctccgacag
     4741 actccatgaa gcccaacaca atgatgttac agcacaacgc tgggtattga ctgagcaaga
     4801 tgaacgacaa gggcaacgac atcagcctca tgatgagcaa gaaaatgaag gtaaattcga
     4861 aaacaatcag aaggacgaaa gttaatgttc ggcctgagaa aagtaaatgg aaacactcat
     4921 tcctttgaaa ccacttttca aaactggaaa gaaaatggtg aagatgttgc gttattaatg
     4981 cccgaattta gcgccaaatg gctaccgata gcagaagaga gcggcagctg gtctggatgg
     5041 gtgttacttc gagagttatt tcccttaatt tctgccgagc tcgctgggat ggctttaatg
     5101 ccagaaacgg aaaggttaat agtggaatgg ctcagtttat ctagtacccc gttaaatcta
     5161 aagtatcctg aactaaaata taatcgtttg tgtgtcggta aagtatttga tggagtattg
     5221 agtccagctc aaccactgat aagaatatgg acaggggaat taaatatttg gttagataaa
     5281 gtcacagtct gccaatacga aaacgctcca acgctagaca aaaaatcatt atattggccc
     5341 attcattttg taattggatt tagtaaaaca tgt
//
LOCUS       DACAOP010000181         5312 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.182, whole genome shotgun sequence.
ACCESSION   DACAOP010000181 DACAOP010000000
VERSION     DACAOP010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5312
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.182"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..1062
                     /gene="murF"
                     /locus_tag="IT892_004379"
     CDS             <1..1062
                     /gene="murF"
                     /locus_tag="IT892_004379"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAP3137502.1"
                     /translation="ARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPM
                     TLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKA
                     KGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHG
                     TEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRL
                     FPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQV
                     GEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLKLLIAEQQVITILVKG
                     SRSAAMEEVVRALQENGTC"
     gene            1056..2138
                     /gene="mraY"
                     /locus_tag="IT892_004380"
     CDS             1056..2138
                     /gene="mraY"
                     /locus_tag="IT892_004380"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAP3137503.1"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     gene            2141..3457
                     /gene="murD"
                     /locus_tag="IT892_004381"
     CDS             2141..3457
                     /gene="murD"
                     /locus_tag="IT892_004381"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAP3137504.1"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
                     DKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     gene            3457..4701
                     /gene="ftsW"
                     /locus_tag="IT892_004382"
     CDS             3457..4701
                     /gene="ftsW"
                     /locus_tag="IT892_004382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HAP3137505.1"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     gene            4698..>5312
                     /locus_tag="IT892_004383"
     CDS             4698..>5312
                     /locus_tag="IT892_004383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HAP3137506.1"
                     /translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVA"
BASE COUNT         1093 a         1294 c         1589 g         1336 t
ORIGIN      
        1 gcgcgcgtgg ttgctctgac ggggtcctcc ggcaaaacct ccgttaaaga gatgacggcg
       61 gcgattttaa gccagtgcgg caacacgctt tatacggcag gcaatctcaa caacgacatc
      121 ggtgtaccga tgacgctgtt gcgcttaacg ccggaatacg attacgcagt tattgaactt
      181 ggcgcgaacc atcagggcga aatagcctgg actgtgagtc tgactcgccc ggaagctgcg
      241 ctggtcaaca acctggcagc ggcgcatctg gaaggttttg gctcgcttgc gggtgtcgcg
      301 aaagcgaaag gtgaaatctt tagcggcctg ccggaaaacg gtatcgccat tatgaacgcc
      361 gacaacaacg actggctgaa ctggcagagc gtaattggct cacgcaaagt gtggcgtttc
      421 tcacccaatg ccgccaacag cgatttcacc gccaccaata tccatgtgac ctcgcacggt
      481 acggaattta ccctacaaac cccaaccggt agcgtcgatg ttctgctgcc gttgccgggg
      541 cgtcacaata ttgcgaatgc gctggcagcc gctgcgctct ccatgtccgt gggcgcaacg
      601 cttgatgcta tcaaagcggg gctggcaaat ctgaaagctg ttccaggccg tctgttcccc
      661 atccaactgg cagaaaacca gttgctgctc gacgactcct acaacgccaa tgtcggttca
      721 atgactgcag cagtccaggt actggctgaa atgccgggct accgcgtgct ggtggtgggc
      781 gatatggcgg aactgggcgc tgaaagcgaa gcctgccatg tacaggtggg cgaggcggca
      841 aaagctgctg gtattgaccg cgtgttaagc gtgggtaaac aaagccatgc tatcagcacc
      901 gccagcggcg ttggcgaaca ttttgctgat aaaactgcgt taattacgcg tcttaaatta
      961 ctgattgctg agcaacaggt aattacgatt ttagttaagg gttcacgtag tgccgccatg
     1021 gaagaggtag tacgcgcttt acaggagaat gggacatgtt agtttggctg gccgaacatt
     1081 tggtcaaata ttattccggc tttaacgtct tttcctatct gacgtttcgc gccatcgtca
     1141 gcctgctgac cgcgctgttc atctcattgt ggatgggccc gcgtatgatt gctcatttgc
     1201 aaaaactttc ctttggtcag gtggtgcgta acgacggtcc tgaatcacac ttcagcaagc
     1261 gcggtacgcc gaccatgggc gggattatga tcctgacggc gattgtgatc tccgtactgc
     1321 tgtgggctta cccgtccaat ccgtacgtct ggtgcgtgtt ggtggtgctg gtaggttacg
     1381 gtgttattgg ctttgttgat gattatcgca aagtggtgcg taaagacacc aaagggttga
     1441 tcgctcgttg gaagtatttc tggatgtcgg tcattgcgct gggtgtcgcc ttcgccctgt
     1501 accttgccgg caaagacacg cccgcaacgc agctggtggt cccattcttt aaagatgtga
     1561 tgccgcagct ggggctgttc tacattctgc tggcttactt cgtcattgtg ggtactggca
     1621 acgcggtaaa cctgaccgat ggtctcgacg gcctggcaat tatgccgacc gtatttgtcg
     1681 ccggtggttt tgcgctggtg gcgtgggcga ccggcaatat gaactttgcc agctacttgc
     1741 atataccgta tctgcgacac gccggggaac tggttattgt ctgtaccgcg atagtcgggg
     1801 caggactggg cttcctgtgg tttaacacct atccggcgca ggtctttatg ggcgatgtag
     1861 gttcgctggc gttaggtggt gcgttaggca ttatcgccgt actgctacgt caggaattcc
     1921 tgctggtgat tatggggggc gtgttcgtgg tagaaacgct ttctgtcatc ctgcaggtcg
     1981 gctcctttaa actgcgcgga caacgtattt tccgcatggc accgattcat caccactatg
     2041 aactgaaagg ctggccggaa ccgcgcgtca ttgtgcgttt ctggattatt tcgctgatgc
     2101 tggttctgat tggtctggca acgctgaagg tacgttaatc atggctgatt atcagggtaa
     2161 aaatgtcgtc attatcggcc tgggcctcac cgggctttcc tgcgtggact ttttcctcgc
     2221 tcgcggtgtg acgccgcgcg ttatggatac gcgtatgaca ccgcctggcc tggataaatt
     2281 acccgaagcc gtagaacgcc acacgggcag tctgaatgat gaatggctga tggcggcaga
     2341 tctgattgtc gccagtcccg gtattgcact ggcgcatcca tccttaagcg ctgccgctga
     2401 tgccggaatc gaaatcgttg gcgatatcga gctgttctgt cgcgaagcac aagcaccgat
     2461 tgtggcgatt accggttcta acggcaaaag cacggtcacc acgctagtgg gtgaaatggc
     2521 gaaagcggcg ggggttaacg ttggtgtggg tggcaatatt ggcctgcctg cgttgatgct
     2581 actggatgat gagtgtgaac tgtacgtgct ggaactgtcg agcttccagc tggaaaccac
     2641 ctccagctta caggcggtag cagcgaccat tctgaacgtg actgaagatc atatggatcg
     2701 ctatccgttt ggtttacaac agtatcgtgc agcaaaactg cgcatttacg aaaacgcgaa
     2761 agtttgcgtg gttaatgctg atgatgcctt aacaatgccg attcgcggtg cggatgaacg
     2821 ctgcgtcagc tttggcgtca acatgggtga ctatcacctg aatcatcagc agggcgaaac
     2881 ctggctgcgg gttaaaggcg agaaagtgct gaatgtgaaa gagatgaaac tttccgggca
     2941 gcataactac accaatgcgc tggcggcgct ggcgctggca gatgctgcag ggttaccgcg
     3001 tgccagcagc ctgaaagcgt taaccacatt cactggtctg ccgcatcgct ttgaagttgt
     3061 gctggagcat aacggcgtac gttggattaa cgattcgaaa gcgaccaacg tcggcagtac
     3121 ggaagcggcg ctgaatggcc tgcacgtaga cggcacactg catttgttgc tgggtggcga
     3181 tggtaaatcg gcggacttta gcccactggc gcgttacctg aatggcgata acgtacgtct
     3241 gtattgtttc ggtcgtgacg gcgcgcagct ggcggcgcta cgcccggaag tggcagaaca
     3301 aaccgaaact atggaacagg cgatgcgctt gctggctccg cgtgttcagc cgggcgatat
     3361 ggttctgctc tccccagcct gtgccagcct tgatcagttc aagaactttg aacaacgagg
     3421 caatgagttt gcccgtctgg cgaaggagtt aggttgatgc gtttatctct ccctcgcctg
     3481 aaaatgccgc gcctgccagg attcagtatc ctggtctgga tctccacggc gctaaagggc
     3541 tgggtgatgg gctcgcggga aaaagatacc gacagcctga tcatgtacga tcgcacctta
     3601 ctgtggctga ccttcggcct cgcggcgatt ggctttatca tggtgacctc ggcgtcaatg
     3661 cccatagggc aacgcttaac caacgatccg ttcttcttcg cgaagcgtga tggtgtctat
     3721 ctgattttgg cgtttattct ggcgatcatt acgctgcgtc tgccgatgga gttctggcaa
     3781 cgctacagtg ccacgatgct gctcggatct atcatcctgc tgatgatcgt cctggtagtg
     3841 ggtagctcgg ttaaaggggc atcgcgttgg atcgatctcg gtttgctgcg tatccagcct
     3901 gcggagctga caaaactgtc gctgttttgc tatatcgcca actatctggt gcgtaaaggc
     3961 gacgaagtac gtaataacct gcgcggcttc ctgaaaccga tgggcgtgat tctggtgttg
     4021 gcagtgttac tgctggcaca gccagacctt ggtacggtgg tggtgttgtt tgtgactacg
     4081 ctggcgatgt tgttcctggc gggagcgaaa ttgtggcagt tcattgccat tatcggtatg
     4141 ggcatttcag cggttgtgtt gctgatactc gccgaaccgt accgtatccg ccgtgttacc
     4201 gcattctgga acccgtggga agatcccttt ggcagcggct atcagttaac gcaatcgctg
     4261 atggcgtttg gtcgcggcga actttggggg caaggtttag gtaactcggt acaaaaactg
     4321 gagtatctgc cggaagcgca cactgacttt attttcgcca ttatcggcga agaactgggg
     4381 tatgtcggtg tggtgctggc acttttaatg gtattcttcg tcgcttttcg cgcgatgtcg
     4441 attggccgta aagcattaga aattgaccac cgtttttccg gttttctcgc ctgttctatt
     4501 ggcatctggt ttagcttcca ggcgctggtt aacgtaggcg cggcggcggg gatgttaccg
     4561 accaaaggtc tgacattgcc gctgatcagt tacggtggtt cgagcttact gattatgtcg
     4621 acagccatca tgatgctgtt gcgtattgat tatgaaacgc gtctggagaa agcgcaggcg
     4681 tttgtacgag gttcacgatg agtggtcaag gaaagcgatt aatggtgatg gcaggcggaa
     4741 ccggtggaca tgtattcccg ggactggcgg ttgcgcacca tctaatggct cagggttggc
     4801 aagttcgctg gctggggact gccgaccgta tggaagcgga cttagtgcca aaacatggca
     4861 tcgaaattga tttcattcgt atctctggtc tgcgtggaaa aggtataaaa gcactgatag
     4921 ctgccccgct gcgtatcttc aacgcctggc gtcaggcgcg ggcgattatg aaagcgtaca
     4981 aacctgacgt ggtgctcggt atgggaggct acgtgtcagg tccaggtggt ctggccgcgt
     5041 ggtcgttagg cattccggtt gtacttcatg aacaaaacgg tattgcgggc ttaaccaata
     5101 aatggctggc gaagattgcc accaaagtga tgcaggcgtt tccaggtgct ttccctaatg
     5161 cggaagtagt gggtaacccg gtgcgtaccg atgtgttggc gctgccgttg ccgcagcaac
     5221 gtttggctgg acgtgaaggt ccggttcgtg tgctggtagt gggtggttct cagggcgcac
     5281 gcattcttaa ccagacaatg ccgcaggttg ct
//
LOCUS       DACAOP010000182         5288 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.183, whole genome shotgun sequence.
ACCESSION   DACAOP010000182 DACAOP010000000
VERSION     DACAOP010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5288
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.183"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(42..1346)
                     /gene="aceA"
                     /locus_tag="IT892_004384"
     CDS             complement(42..1346)
                     /gene="aceA"
                     /locus_tag="IT892_004384"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HAP3137507.1"
                     /translation="MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECT
                     LAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLA
                     ASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEA
                     GFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARL
                     AADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRG
                     LAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIA
                     SFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKD
                     GYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF"
     gene            complement(1376..2977)
                     /gene="aceB"
                     /locus_tag="IT892_004385"
     CDS             complement(1376..2977)
                     /gene="aceB"
                     /locus_tag="IT892_004385"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase A"
                     /protein_id="HAP3137508.1"
                     /translation="MTEQATTTDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQR
                     NKLLAARIQQQQDIDNGTLPDFISETASIRDADWKIRGIPADLEDRRVEITGPVERKM
                     VINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNP
                     AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQS
                     WQEAAWWSEVFSYAEDRFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGR
                     WDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFI
                     PSKDEEHNNQVLNKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEV
                     MREQDAPITADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAAT
                     AEISRTSIWQWIHHQKTLSNGKPVTKALFRQMLGEEMKVIASELGEERFSQGRFDDAA
                     RLMEQITTSDELIDFLTLPGYRLLA"
     gene            complement(3246..4175)
                     /gene="metA"
                     /locus_tag="IT892_004386"
     CDS             complement(3246..4175)
                     /gene="metA"
                     /locus_tag="IT892_004386"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HAP3137509.1"
                     /translation="MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLM
                     PKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQDQNFDG
                     LIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTR
                     TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGD
                     AYLFASKDKRIAFVTGHPEYDAQTLAQEFFRDVEAGLDPDVPYNYFPHNDPQNTPRAS
                     WRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD"
     gene            4332..4775
                     /locus_tag="IT892_004387"
     CDS             4332..4775
                     /locus_tag="IT892_004387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP3137510.1"
                     /translation="MVISIRRSRHEEGEELVAIWCRSVDATHDFLSAEYRTELEDLVR
                     SFLPEAPLWVAVNERDQPVGFMLLSGQHMDALFIDPDVRGCGVGRVLVEHALSMAPEL
                     TTNVNEQNEQAVGFYKKVGFKVTGRSEVDDLGKPYPLLNLAYVGA"
     gene            complement(4838..5221)
                     /locus_tag="IT892_004388"
     CDS             complement(4838..5221)
                     /locus_tag="IT892_004388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137511.1"
                     /translation="MSVLYIQIRRNQITVRDLESKREVSGDAAFSNQRLLIANFFVAE
                     KVLQDLVLQLHPRSTWHSFLPAKRMDIVVSALEMNEGGLSQVEERILHEVVAGATLMK
                     YRQFHIHAQSAVLSDSAVMAMLKQK"
BASE COUNT         1265 a         1336 c         1355 g         1332 t
ORIGIN      
        1 aacgccttat ccggcctaca gtcagcaacg gttgttgttg cttagaactg cgattcttca
       61 gtggagccgg tcagcgcggt gactgaagac gtgccgccct gaataatagt cgtcacttta
      121 tcgaagtaac ctgtacccac ttcctgctgg tgagatacga aggtatagcc atctttcgcg
      181 gcggcaaatt ccggctgctg cactttctca acgtagtgct tcataccctc gccctgggca
      241 taggcgtttg ccaggtcaaa catgttgaac cacatgctgt ggatacctgc cagggtgatg
      301 aactggaact tgtagcccat atccgacagc tgctgctgga agctggcaat agttttgtcg
      361 tcgaggtttt tctgccagtt gaacgacggc gagcagttat aagccagcag tttgcccgga
      421 tatttcgcgt ggatagcttg tgcaaagcga cgcgccagtt ccagatccgg cgtggaggtt
      481 tcacaccaga ccaggtcagc atatggcgca tacgccaggc cacggctgat cgcttgctca
      541 atgcccgcat gagtacggaa gaagccttca ctggtacgct cgccggtaat aaattcgctg
      601 tcatacgggt cgcaatcgga ggtgatcaga tccgccgcat cagcatcggt acgggcaacc
      661 agcagggttg gaacgcccgt cacgtcagct gccagacgcg ccgcgaccag tttctgaata
      721 gcttcctgag ttggcactaa aactttgccg cccatgtgac cgcatttctt cactgacgcc
      781 agctgatctt cgaagtgaac tgccgctgca ccggcttcaa tcatcgcttt catcagttca
      841 aaggcattca ggacaccgcc aaaaccggct tccgcatcgg caacgatcgg caggaagtaa
      901 tcgacatagc gcggatcgcc cggctcaatg cccgcggacc attggatctg atcggcacga
      961 cggaaggtgt tgttgatccg ctccaccaca gctggcaccg agtttgccgg atagagcgac
     1021 tgatccggat acatgctggc cgccaggtta gcgtccgccg ctacctgcca tcccgacaga
     1081 tagactgctt caatacccgc tttcgcctgt tgcagcgcct gaccgccagt cagtgcgccg
     1141 aggctgttga tgtagccttt tttcgactca ccgtgcagca gacgccacat tttcgctgcg
     1201 cccagttgcg ccagcgtgca ttcaggattg actgaaccgc gtaatttcac cacatcttcc
     1261 gcactgtatg ggcgagtaat gccttcccaa cgcggttgag tccactcttt ctgtaattct
     1321 tcaatttgtt gtgtacgggt tttcatgtgc agatgctcca tagttatgtg gtggtttacg
     1381 ctaacaggcg gtagcctggc agggtcagga aatcaattaa ctcatcggaa gtggtgatct
     1441 gttccatcaa gcgtgcggca tcgtcaaaac gcccctggga gaaacgttct tcgcccagtt
     1501 cgctggcaat gactttcatc tcttcgccca gcatctggcg gaacaaggct ttggtcaccg
     1561 gtttgccatt gctcaacgtt ttttgatgat ggatccactg ccagatcgag gtacgggaaa
     1621 tttcagccgt cgccgcatct tccatcaggc cataaatcgg cacacagccg ttgccagaga
     1681 tccacgcttc gatgtactgc acagccacgc gaatgttggc gcgcatacct tcttcggtgc
     1741 gttcaccatc acaaggtgcc agcagctgat cggcagtaat cggcgcgtct tgttcgcgca
     1801 tcacttcaag ctgattttta cgggagccga gaatgtcgtt gaataccgcc attgccgtgt
     1861 ccgcaaggcc tgggtgagcg atccatgtgc catcgtgacc gttattggct tccagcgatt
     1921 tatccgcttt tactttgttg agcacctggt tattgtgctc ttcatctttg ctcggaataa
     1981 acgccgccat gccgcccatc gcaaaagcac cgcgtttatg gcaggtttta atcaacaggc
     2041 gtgagtaagc attcaggaat ggtttatcca tcgtcactgc ctgtctgtct ggcaggacgc
     2101 gatcgggata gtttttcaac gttttgatat agctgaagat gtaatcccaa cgaccgcagt
     2161 tcagaccaac aatatggtca cgcagcgcgt gaaggatttc atccatctgg aacacggcgg
     2221 gcagcgtttc aatcagcaac gtcgccttga tggtgccgcg cggcagatta aagcgatctt
     2281 ctgcatagct gaagacttcg ctccaccagg ccgcttcctg ccaggactgg gttttcggca
     2341 gatagaaata gggaccactg ccctttgcca acagtgcctg atagttgtgg aagaaataga
     2401 gcgcaaaatc aaacaggctg ccggggattg cctcaccacg ccaggtgaca tgtttttccg
     2461 gcaagtgcag accgcgtacc cgacaaatca aaaccgctgg attgggcttg agctggtaaa
     2521 ttttgcctgc ttcattggtg taactgatgg tgccgttaac cgcatcacgc aggttaattt
     2581 gcccgtcgat cactttgttc cagtctggtg ccagtgaatc ttcgaaatcg gccataaaga
     2641 ctttcacatt ggcgttgagc gcgttgatca ccatcttgcg ctctaccggg ccagttatct
     2701 ctacgcggcg gtcttctaag tccgcaggaa tcccgcgaat tttccaatca gcatcgcgaa
     2761 tggaagctgt ttccgaaata aaatcaggca acgttccgtt atcaatatct tgctgctgct
     2821 gaatgcgcgc tgccagaagt ttattgcgtt gtggcgtaaa atgcgtcacc agctcagtca
     2881 gaaattctac cgcttcggca gtaagaattt gcttctcctg ctcgccatac ggccttgtga
     2941 aagccagttc atcggttgtt gttgcctgtt cagtcatcgt gcagctcctc gtcatggatc
     3001 cgaaaacttc cccactgtga acgaaggatc gttgtgctct tttcgttcag cacaactaag
     3061 actactcatt taaaatgcaa aatcaaaaac aatttccatt ttaattaaaa atacttgata
     3121 acttgttgat aacaatatga ataaaattta ttcacctgct gaggtacgtt tcggaaataa
     3181 aaaaggcacc cgaaggtgcc tgaggtaagg tgctgaatcg cttaacgatc gactatcaca
     3241 gaagattaat ccagcgttgg attcatgtgc cgtagatcgt atggcgtgat ctggtagacg
     3301 taatagttga gccagttggt aaacagtaaa ttaccgtgac tacgccagct cgctcgcggt
     3361 gtattttgcg gatcattgtg cgggaaatag ttatacggta catccgggtc tagtccggct
     3421 tccacatcgc ggaaaaattc ctgcgccagc gtttgcgcat catattcggg atggcccgtc
     3481 acaaaggcaa tgcgcttatc tttactggca aacagatatg catccccttc ttccgtctct
     3541 gccagaattt ccagatcggt gtaatcacga atcaacgctg ccggaaagtc agcatagcgc
     3601 gaatgcggtg ccaggaatga atcatcaaag ccacgcgtca gaagcgcatg aggatggaga
     3661 atatgatgct cgtaaacgcc agagagtttg tcggtgcgag tttgcttagg aatgccgtag
     3721 aggatattga gcgcggcctg taccgcccag cagacaaaca gcgtcgaggt gacgtgatct
     3781 ttcgaccact ccagcacctg tttgatctgc ggccagtaag cgacatcatt aaactccacc
     3841 aggcccagcg gcgcaccagt tacaatcaaa ccgtcaaagt tctgatcctg aatatcttca
     3901 aagttacagt agaagttgtt cagatgctct gcgggcgtgt tgcgcgattc acgggaatcg
     3961 atgcgcaaca gctgaatatc gacctgcaaa ggtgagtttg aaagcaggcg cagaaactga
     4021 ttttcagttt caatcttctt cggcatcagg ttaaggatca gaaccttaag tggacgaatt
     4081 tcctgaccag acgcacgaga agttgtcatc acaaagacgt tttcttcacg caagaaattg
     4141 acggcgggta gctcgtccgg cacacgaatc ggcataacct gattacctca ctacatacgc
     4201 ttatacgttt agacatccag atagctgaag ataaccagaa aatttgccaa tgtcgagcct
     4261 gcatgttgaa ggtgagaaag tttcaaggaa aagactacgt tagaatataa gaatgactaa
     4321 aaggagagaa aatggttatt agtattcgcc gctcacggca tgaggaaggg gaggaactcg
     4381 ttgcgatttg gtgtcgttct gtcgatgcca ctcacgattt tctatcagca gagtatcgga
     4441 ccgagctgga ggacctagtt cgttccttcc tgccggaagc gccgttgtgg gtcgcggtta
     4501 atgagcggga tcagccggtt ggatttatgt tgctaagtgg gcagcatatg gatgcgctgt
     4561 ttatcgatcc tgatgtgcgc ggctgcggcg taggtcgggt gctggtggag catgcgctct
     4621 cgatggcacc ggaactgaca accaacgtta atgagcaaaa tgagcaggcg gttgggttct
     4681 ataagaaggt gggttttaag gttacgggac gctctgaggt ggacgatttg gggaaaccgt
     4741 atccgttgct gaatctggcg tatgtggggg cgtaggcgat tttttctcat cccggtgggc
     4801 tgaacttcag gtttagtacc caccaatggt gacacgatta tttctgctta agcattgcca
     4861 tgaccgcact atcactgagt accgctgatt gcgcatggat gtggaactgg cgatatttca
     4921 ttaacgttgc cccagcgacc acttcatgga gaatgcgttc ctcaacctgt gacaaaccgc
     4981 cctcattcat ttccagcgcg ctcacaacaa tatccatacg ttttgctggc aaaaaagaat
     5041 gccaggttga acgtgggtgg agttgcagaa caagatcttg cagaactttt tctgcaacaa
     5101 agaaattggc gattaacagg cgctggttac tgaaggcagc gtctcctgac acttcacgtt
     5161 tgctttcaag atcgcgaaca gtaatttgat tacgacgaat ttggatatac agaactgaca
     5221 tgagattccc ttcatcatgc aaataattga tatgcaaaaa accccggcct tatggaccgg
     5281 ggtttttc
//
LOCUS       DACAOP010000183         5049 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.184, whole genome shotgun sequence.
ACCESSION   DACAOP010000183 DACAOP010000000
VERSION     DACAOP010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5049
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.184"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..588
                     /locus_tag="IT892_004389"
     CDS             <1..588
                     /locus_tag="IT892_004389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137512.1"
                     /translation="EKIGNNQAITVTNNQIQNIGLNQIQTVGVNQVETVGSNQIIKVG
                     SNQVEKVGIIRALTVGVAYQTTVGGIMNTSVALLQSSQVGLHKSLMVGMGYSVNVGNN
                     VTFSVGKTMKENTGQTAVYSAGEHLELCCGKARLVLTKDGSIFLNGTHIHLEGESDVN
                     GDAPVINWNCGATQPVPDAPVPKDLPPGMPDMRQF"
     gene            664..4896
                     /locus_tag="IT892_004390"
     CDS             664..4896
                     /locus_tag="IT892_004390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HAP3137513.1"
                     /translation="MGGGKPAARQGDMTRKGLDIVQGSAGVLIGAPTGVACSVCPTKK
                     DSPNYGSPVNPLLGAKVLPVETDLALPGPLPFILFRAYSSYRTRTPAPVGVFGPGWKA
                     PFDIRLQVHERELILNDSGGRSIHFESLFPGEISYSRSESFWLARGGVLKQHKGHPLA
                     RLWRALPEAVRLSPHTYMMAVSTTGQWLILGWPERVPEADEVPPPEPPAYRVLTGVVD
                     GFGRTLTFHRAAEGDVAGAVTGVTDGAGRCFHLVLSTQAQRAEAFRKQRESSLSSPAG
                     PRSASSSQVFPDTLPAGTEYGADNGIRLEAVWLTHDPAYPDEQPTAPLARYTYTASGE
                     LRAVYDRSGTQVRGFTYDAEHAGRMVAHHYAGRPESRYRYDDTGRVTEQVNPEGLDYR
                     FEYGESRVIITDSLNRREVLYTEGEGGLKRVVKKEHADGSITRSEYDEAGRLKAQTDA
                     AGRRTEYRLHMASGKLTSVILPDGRTVRYGYNSQLQLTSVTYPDGLRSSRKYDRQGRL
                     AEETSRNGNITRWFYDFSRSGLPCAVEDGTGVRRRITRNRYGQLLAFTDCSGYTTRYE
                     YDQYGQQIAVHREEGISTYSSYNPRGQLISRKDAQGRETRYEYSAAGDLTATISPDGK
                     RSATEYDKRGRPVSVTEGGLTRSMGYDAAGRITVLTNENGSQSTFRYDPVDRLTEQRG
                     FDGRTQRYQYDLTGKLTQSEDEGLITLWHYDASDRITRRTVNGEPAEQWQYDDHGWLT
                     EISHLSEGHRVAVHYGYDDKGRLTGERQTVENPETGEMLWEHETGHAYSEQGLATRQE
                     PDGLQPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETARSFGGEAYELATAWNTSG
                     QLRSRHLNLPQLDRDYDWNDNGQLIRISGPQESREYRYSDTGRLTGVHTTAANLDIDI
                     PYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYRHDEYGRLAEKTDRIPEGVI
                     RMHDERTHHYHYDSQHRLVFYTRIQHGEPQVESRYLYDPLGRRTGKRVWRRERDLTGW
                     MSLSRKPEVTWYGWDGDRLTTIQTGTTRIQTVYQPGSFTPLLRIETENGEQAKARHRS
                     LAEVLQEDTGVTLPAELAVMLGRLERELRAGAVSAESEAWLAQCGLTAEQMAAQMEDA
                     YIPERRLHLYHCDHRGLPQALITPEGETAWCGEYDEWGNQLNEENPHHLYQPYRLPGQ
                     QYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGINLYTYPLVPIRYTDPLGLERVIS
                     VYGPPAPDRAGAETPLVLTDMTGGVTIYYDPETGDSMTFDSSNRIDRRSQRGAGDPYT
                     GEVVGCETNESGISAAYGTTKIYTTDTRARWLHGGGSSLRDPYAPRQGWKPTMGCTRA
                     QNEDVDELCKKVTSWMYSHPGERIRYERFKTR"
BASE COUNT         1186 a         1272 c         1683 g          908 t
ORIGIN      
        1 gaaaaaatag gtaacaacca ggcgatcacc gttaccaata accagatcca gaacattggc
       61 cttaatcaga tacagacggt tggtgtcaac caggtggaaa cggtgggtag taaccagatt
      121 atcaaagtgg gatcaaacca ggttgaaaag gtggggatca ttcgtgcgct gacggtgggt
      181 gtggcttacc agacgacggt aggcggcatt atgaatacct cggtggcgtt gttgcagtcc
      241 tcacaggtag ggctgcataa atcactgatg gtgggaatgg gctacagcgt caatgtgggg
      301 aataacgtca ccttctcggt gggcaagacg atgaaggaaa acaccggaca aacagcagtt
      361 tattctgccg gtgagcatct tgaactctgc tgtggtaagg caaggctggt gctgacgaag
      421 gacggaagca tatttctcaa cggtacgcac attcatctgg aaggggagtc ggatgtgaac
      481 ggtgatgcgc cagtgattaa ctggaactgt ggtgccacac aacctgtacc ggatgcgcct
      541 gtgccgaaag atttaccccc cggaatgccg gatatgcggc aattttgagt caggtgcaaa
      601 aaattaaaac ggaactggtg cagtgaccag atgaaccata ttaaaagcag aaggaattga
      661 ttcatgggcg gcggaaaacc ggcggcgcgg cagggtgaca tgacccgcaa gggactggat
      721 attgtgcagg gttcagcagg ggtgctgata ggtgcgccaa ccggtgtggc ctgctcggtg
      781 tgtcccacaa aaaaggacag tccgaactat ggcagcccgg tgaacccgct actcggtgcg
      841 aaggttctgc ctgttgaaac cgacctggca ctgcccggcc cgctgccgtt tattcttttc
      901 cgcgcctaca gcagctaccg gaccaggacg cccgcgccag tgggcgtgtt tggtcccggc
      961 tggaaagcgc ccttcgatat ccgcttacag gttcatgagc gggaactgat actcaacgac
     1021 agcggcggca ggagcattca ctttgagtcg ctgtttcccg gcgagataag ctacagccgc
     1081 agcgagtcgt tctggctggc aaggggcgga gtgctgaaac aacacaaagg ccatccgctt
     1141 gcgcggctct ggcgggcgtt gccggaagcg gtccgtctga gtccacacac ctatatgatg
     1201 gctgtcagca caaccgggca gtggctgata ctcggctggc cggagcgtgt gccggaggcg
     1261 gacgaggtgc cgccgccgga gccgcccgca taccgggtgc tgacgggcgt ggtggacggc
     1321 ttcgggcgga cgctgacttt ccaccgggcg gcggagggtg acgtggcggg cgcggtgacg
     1381 ggggtgacgg acggtgcggg ccgctgtttt cacctggtgc tgagcacaca ggcgcagcgg
     1441 gcagaagcct tccgtaaaca gcgcgagtct tccttatctt ctccagccgg tccccgttct
     1501 gcttcctctt ctcaggtttt ccccgacacg ctgcccgccg gtacagagta cggtgccgat
     1561 aacggtatcc ggctggaggc ggtgtggctg acacacgacc cggcataccc ggatgaacag
     1621 ccgactgcgc cgctggcgcg ctacacgtac acggccagcg gagaactgcg ggcggtgtat
     1681 gaccgcagcg ggacgcaggt tcgcgggttt acttatgatg cggagcacgc cgggcggatg
     1741 gtggcgcacc attatgcggg gaggccggag agccgctacc ggtatgatga taccggtcgg
     1801 gtgacggagc aggtcaaccc ggaggggctg gactaccgct ttgagtacgg agagagccgg
     1861 gtaatcatca cggacagcct gaaccggcgg gaggtgctgt acacggaagg cgagggtggc
     1921 ctgaagcggg tggtgaagaa ggagcatgcc gacgggagca tcacccgcag cgagtatgat
     1981 gaggcgggga ggctgaaggc gcagacggat gcggcggggc ggcggacgga gtaccggctg
     2041 catatggcgt ctggaaagct gacttcagtg atactgccgg acggcaggac ggtgcggtat
     2101 ggctataaca gccagttgca actgacttca gtgacatatc cggatggttt acgcagcagc
     2161 cggaaatatg accgtcaggg ccgactggca gaagagacct cgcgcaacgg taacattacg
     2221 cgctggtttt atgatttttc ccgcagtggc ctgccctgtg cggtggaaga cggaaccggg
     2281 gtgaggcgga gaataacgcg aaaccgttac ggtcaactgc tggcctttac ggactgctcg
     2341 gggtacacga cgcggtatga gtacgaccag tacggtcaac aaatcgccgt tcaccgggaa
     2401 gaaggcatca gcacttacag cagttataac ccgcgtggcc aactgatcag tcggaaggat
     2461 gcgcaggggc gtgaaacccg ttatgagtac agcgctgcag gcgacctgac agcaacgata
     2521 tcaccggacg gtaaacgcag cgccaccgaa tatgataaac gtgggcgtcc ggtgagtgtg
     2581 acggaaggtg gactgacgcg cagcatgggg tatgacgccg ccgggcgcat caccgtgctg
     2641 actaacgaga acggcagcca gtccacgttc cggtatgacc cggtggacag gctgacggag
     2701 cagcgcggct ttgacggccg gacgcaacgt taccagtatg acctgaccgg aaaactcacg
     2761 cagagtgaag acgaggggct tatcaccctc tggcattacg atgcgtcaga ccgtatcacc
     2821 cggcgcacgg tgaacggtga accggcggag cagtggcagt atgacgacca cggctggctg
     2881 acagaaatca gccacctgag tgaaggccac cgtgtggcgg tccactacgg ctatgacgat
     2941 aaaggccgcc tgacgggcga acggcagacg gtggagaacc cggagacggg ggagatgctg
     3001 tgggagcatg agacggggca tgcgtacagc gaacaggggc tggcgacccg tcaggagccg
     3061 gacggtctgc agccggtgga gtggctgacg tatggcagcg gttatcttgc ggggatgaag
     3121 ctgggcggaa caccgctggt cgagtacacg cgggacaggc tgcaccgtga gacggcccgc
     3181 agcttcggcg gggaggcata tgaacttgcc accgcctgga ataccagcgg ccagctccgg
     3241 agcaggcacc tgaaccttcc gcagcttgac cgtgactacg actggaacga caacggacag
     3301 ctaatccgca tcagcggccc gcaggagagc cgggagtacc gttacagcga cacgggaagg
     3361 ctgacgggcg tccacaccac ggcggcgaac ctggatatcg atatcccgta tgcgacggac
     3421 ccggcaggaa accggctgcc ggacccggaa ctgcacccgg acagcacgct cacggcatgg
     3481 ccggataacc gcatcgcgga agatgcgcac tatgtctacc gccacgatga atacggcagg
     3541 ctggcggaga agacggaccg catcccggaa ggggtgatac ggatgcacga cgagcggacc
     3601 caccactacc actacgacag ccagcaccgc ctggtgttct acacgcggat acagcacggc
     3661 gaaccacagg tggagagccg gtacctctat gacccgctgg gccgccggac gggaaaacgg
     3721 gtatggcggc gggagcgtga cctgacgggg tggatgtcgc tgtcgcgtaa accggaggtg
     3781 acatggtacg ggtgggacgg tgacaggctg acgacgatac agaccggcac cacgcgtatc
     3841 cagacggtat accagccggg gagcttcacg ccgctcctga gaatcgaaac agagaatggc
     3901 gaacaggcga aggcgcggca ccggagcctg gcggaggtgt tgcaggagga cacgggtgtg
     3961 acgctaccgg cggagctggc ggtgatgctg ggaaggctgg agcgggagct gcgtgcggga
     4021 gcggtgagtg cggagagtga ggcatggctt gcgcagtgcg ggctgacggc ggaacagatg
     4081 gccgcgcaga tggaggatgc atacatcccg gagcggaggc tgcatcttta ccactgtgac
     4141 caccgtggac tgccgcaggc gctcatcacc ccggaaggcg aaacggcgtg gtgcggggag
     4201 tatgacgagt gggggaacca gcttaatgag gagaacccgc atcacctgta ccagccgtac
     4261 cgtttgccgg ggcagcagta tgatgaggag tcgggactgt attacaaccg tcaccggtac
     4321 tacgatccgt tgcaggggcg gtatatcacc caggatccga tagggttgaa ggggggaata
     4381 aatctataca cgtatccact ggtaccaata cgttacactg atccactggg gttagaacga
     4441 gttataagtg tatatgggcc tcccgctcca gaccgggcag gtgctgaaac tcctcttgtt
     4501 cttactgata tgactggagg agtgactatt tattatgatc ctgaaacagg tgattcaatg
     4561 acttttgata gtagcaatag aattgatcgt cgttctcaac gtggtgctgg tgatccatat
     4621 acaggtgaag tcgttggttg tgagacaaat gaatcaggaa tatcggcagc atatggcaca
     4681 acgaagatct atactacaga tactagagca agatggctac atggtggggg atcatcgttg
     4741 cgcgatcctt atgctcctcg acaaggctgg aaaccaacta tgggatgtac ccgtgcacag
     4801 aatgaagatg tagatgagtt gtgtaagaaa gtgacaagtt ggatgtattc gcatcctgga
     4861 gagagaatta gatatgaacg ttttaagaca cgttaatgcg attaacatgg gagtgtgcat
     4921 tctaatttgg gttattggat gtgcaaatgc taaagttctt aaacgatgta tattacctgc
     4981 tcctgatggt ggcgtagaaa aactatcaaa acccaactta catggagtaa ttaaaaaagt
     5041 tgatttgaa
//
LOCUS       DACAOP010000184         5004 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.185, whole genome shotgun sequence.
ACCESSION   DACAOP010000184 DACAOP010000000
VERSION     DACAOP010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5004
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.185"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(24..758)
                     /locus_tag="IT892_004391"
     CDS             complement(24..758)
                     /locus_tag="IT892_004391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscJ/YscJ/HrcJ family type III secretion inner
                     membrane ring protein"
                     /protein_id="HAP3137514.1"
                     /translation="MKYISLFLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINA
                     EKKDQGKTGFSIYVEPTDFASAVDWLKIYNLPGKPDIQISQMFPADALVSSPRAEKAR
                     LYSAIEQRLEQSLKIMDGIVSSRVHVSYDVDTGDSGKTALPIHISVLAVYEKDINPEI
                     KINDIKRFIVNSFASVQYENISVVLSKRRDIIEQAPTYEINEPVFAYDKTMPVSILLA
                     LMSIATCWLLWKYRAILTNLIRLKNK"
     gene            complement(755..1087)
                     /locus_tag="IT892_004392"
     CDS             complement(755..1087)
                     /locus_tag="IT892_004392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137515.1"
                     /translation="MSVSNMPPIDRAEQAAAREIQQAKVIDLNDRVLNLDNPDDKMIS
                     AFANYAVQTENWQQNALQALRSDKKGLTPEKLLVLQDHVLNYNVEVSLVGTLARKIVA
                     AVETLTRS"
     gene            complement(1107..1346)
                     /locus_tag="IT892_004393"
     CDS             complement(1107..1346)
                     /locus_tag="IT892_004393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system needle complex
                     protein"
                     /protein_id="HAP3137516.1"
                     /translation="MADWNGYIMDISKQFDQGVDDLNQQVEKALEDLATNPSDPKFLA
                     EYQSALAEYTLYRNAQSNVVKAYKDLDSAIIQNFR"
     gene            complement(1360..2541)
                     /locus_tag="IT892_004394"
     CDS             complement(1360..2541)
                     /locus_tag="IT892_004394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001365813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgH/EprH family type III secretion apparatus
                     protein"
                     /protein_id="HAP3137517.1"
                     /translation="MENNDKFLSQDLLESYAIRLLSGPLNGCEYEILNGRVLVIVGND
                     VSLGRSDSFSELPENTIVIPYGELTGSFEVIITTDPDLVVTIRELTAQEPEDRTLTLN
                     QQIEVLGLKFAVKVKNEVWQYSIPGIVENNITSTRQHFFSSTLFKYVTLFFLFAIIFI
                     AFYIVNASNDPQLRHIDKILVNKNRNYEILYGRDHVIYINTNSLDEAVWVKQALEKNQ
                     PGKPVRVINPDDESIRIFSWLADNFPDLQYFKLQLLDASNPRLTVSKQRNAITQQLID
                     NLIKGLLQTMPYASNISIAVLDDNVLESQAIETLSAIGISYEKYKTANNVYFNIIGTL
                     SDSELNKINNYVDGYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQGSKWTFQ
                     E"
     gene            2800..3300
                     /locus_tag="IT892_004395"
     CDS             2800..3300
                     /locus_tag="IT892_004395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP3137518.1"
                     /translation="MQVFSSDVYFTVGTNALLASQKEYYSDLVALVDLGHSFVVIDEH
                     QHRNLKPNTEPVNTLLSNNFIRINKNITLSDLTHFLVSNLHTQNVYSTQEPLTHDEID
                     ILRLCVSYSLKQIAIIKGIDYKTVSYHKIRALNKLNIKGTVELFIALCEWDKHYFKLQ
                     SCIRES"
     gene            3330..3596
                     /locus_tag="IT892_004396"
     CDS             3330..3596
                     /locus_tag="IT892_004396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="invasion protein"
                     /protein_id="HAP3137519.1"
                     /translation="MIITVALISLLSACTRENSLKDTQNKISGESQAIVDARQFFSEH
                     PEYISSAELEQKLYREFAQVTTVPAYKEMSMYQLLVISQDRLTH"
     gene            complement(3666..4790)
                     /locus_tag="IT892_004397"
     CDS             complement(3666..4790)
                     /locus_tag="IT892_004397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscU/YscU/HrcU family type III secretion system
                     export apparatus switch protein"
                     /protein_id="HAP3137520.1"
                     /translation="MECFTANKTEKPTQKKLQDASKKGQILKSRDLTVCVIMLVGTLY
                     LGYVFDVHHIMSILEYILDHNAKPDIWDYFKAMGIGWLKTIIPFLLVCMFTTILVSWF
                     QSKMQLATEAIKFKFDSLNPVNGLKRIFGLKTVKEFVKAILYIIFFALAIKLFWSNHK
                     SLLFKTLDGDIISLLSDWGEMLFLLILYCLGSMIIVLIFDFIAEYFLFMKDMKMDKQE
                     VKREYKEQEGSPEIKSKRRERHQEILSEQLKSDVSNSRLMIANPTHIAIGIYFKPHLS
                     PIPLISVRETNEVALAVRKYAKEIGIPIITDKKLARKIYATHRRYDYVSFENIDEILR
                     LLLWLEDVENAGQPVPDELLPSEDKFKEGEDTKSENKDNN"
     gene            complement(4787..4981)
                     /locus_tag="IT892_004398"
     CDS             complement(4787..4981)
                     /locus_tag="IT892_004398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein"
                     /protein_id="HAP3137521.1"
                     /translation="MLGGEAVLGLLARYASQLNAFAISLTVKSALAFLILIIYFGPIL
                     AERVMPLSFFPEQLQLYIDK"
BASE COUNT         1588 a          950 c          793 g         1673 t
ORIGIN      
        1 agattcataa cgttctcata tgtctactta ttttttaacc tgattaaatt agttagaata
       61 gccctgtact tccataacag ccagcaagtc gcaatggaca ttaatgcaag taagatagaa
      121 accggcatag tcttatcata agcaaaaaca ggttcgttaa tttcatatgt tggtgcttgt
      181 tcaataatat ctcttcgttt tgacaatacg actgaaatat tctcatattg tacgcttgca
      241 aagctattaa caataaatct cttaatgtca tttattttta tttctggatt gatatctttt
      301 tcatatacag caagtacaga aatatgaatt ggtaaagcag ttttgccact atcacctgta
      361 tcaacatcgt aactaacatg tactcttgaa gaaacaatgc catccataat tttgagagat
      421 tgctctaaac gctgttcaat agcagaatac aatcttgctt tttccgctcg tggagaggaa
      481 acgagcgcat ctgcagggaa catctgcgat atttgaatat caggcttacc cgggagattg
      541 tagattttta gccaatccac cgcagaagca aaatccgttg gttctacata gattgaaaat
      601 ccagttttgc cttgatcctt cttctcagca ttaatattat gtctttgtaa aacagcaagg
      661 acatcattag cttgctgttg atcaagatgg ttcagtaatt cctgctgctt gcaaccgcac
      721 aacagcagga taaacaagaa taatgatata tatttcatga gcgagtcaac gtctcaactg
      781 cagcgacaat ttttcttgct aatgttccca ccaatgaaac ctcgacatta taattaagca
      841 catgatcctg caagactaat aatttttcag gagttaaccc ctttttatca gaccttaatg
      901 cttgtaacgc attttgctgc caattttcag tttgtaccgc atagttggca aaagcggaaa
      961 tcattttatc atccgggtta tcaagattga gaacccggtc atttaaatca ataactttcg
     1021 cttgctgtat ttcacgagca gctgcttgct cagctctatc aataggtggc atattgctta
     1081 ctgacataat aaaatcctta tccagtttag cggaagtttt gtatgattgc cgaatcaaga
     1141 tctttatacg cttttacaac gttagattgc gcatttcgat ataatgtata ctcagctaat
     1201 gcactctgat attcggcaag gaatttcggg tcggaaggat tggttgctaa atcctccaac
     1261 gccttttcaa cttgttggtt cagatcatca acgccctgat caaattgttt gctgatatcc
     1321 ataatataac cattccaatc tgccataagt cctcctcaat tattcctgaa atgtccactt
     1381 gctaccttga gacttctcga atcggttatc tccgtagcta aatgaactat tatttgtatc
     1441 ctgatttttc aaattcacat taaatcttac atattgttta ccccattgct tataatatcc
     1501 gtcgacatag ttattaattt tatttaattc actgtcgctt aacgtaccaa tgatattaaa
     1561 atatacattg ttagctgttt tatatttttc ataagaaata cctattgccg acaatgtttc
     1621 aattgcctga ctttccaata cattatcatc taataccgca atacttatat tgctggcata
     1681 tggcatagtt tgcagtaatc ctttaataag attatcgatt agttgctgtg tgatagcatt
     1741 ccgttgctta ctcactgtca gtcttggatt actggcatct aatagctgta gtttaaaata
     1801 ttgtagatct gggaaattat cagcaagcca tgaaaaaatc cgtatcgatt catcatcagg
     1861 atttatcacc cgtactggct ttcctggttg atttttttcc agtgcttgtt tgacccagac
     1921 agcttcatcc aaactattgg tattgatata gatgacatga tccctaccat ataaaatttc
     1981 ataatttcta tttttgttta caagaatttt atcgatatgt ctcagctgcg gatcattact
     2041 ggcattaaca atataaaaag ctataaaaat gatagcaaaa agaaaaaata gcgttacata
     2101 tttaaacagc gtactactaa agaaatgttg tcttgttgaa gtaatgttat tttcaacaat
     2161 acctggtatt gaatactgcc aaacttcatt ttttactttt acagcaaatt tgaggcctaa
     2221 aacttctatt tgctgattca atgttaacgt tctatcttca ggttcttgtg ctgttaattc
     2281 tctgattgtt acaaccagat cagggtcggt agtgattatt acctcaaaac tgcctgtaag
     2341 ctctccataa ggaatgacta tcgtattctc tggtaactca gaaaaagaat cacttcttcc
     2401 taacgaaaca tcattaccaa cgataacgag tacacgccca ttaagtattt catactcgca
     2461 tccattcaat ggtccgctca ataaacgaat ggcataagat tccaataagt cttgtgataa
     2521 gaatttatca ttattttcca tgaataccac ccgctaattc cataagctct agtttagagt
     2581 agtgtaacaa gacggaaatt tcatgaccaa attatgatga cacacaataa aaagattata
     2641 attttcgaga accattttaa atgcctacat acataacttt atttgcaatt taaggtatac
     2701 accctattcc ctcattgata tgcaaatata acaattacca ttattttaaa ttttacacgt
     2761 aatatttacc ctaaatgatt ttagagtgca ggttggcata tgcaagtctt ttccagtgat
     2821 gtctacttca ctgtaggcac taatgcatta ttagcatccc aaaaggaata ttacagcgat
     2881 ttggttgcgt tggttgatct tggacattcg ttcgttgtta ttgatgagca ccaacatcga
     2941 aatctcaaac caaatacaga acctgtaaac acccttttga gcaacaattt catcaggatc
     3001 aataagaata ttacattatc tgatttaacg catttcctgg tttcgaatct tcatacacaa
     3061 aatgtgtatt ccactcaaga accacttacc catgatgaga tagatatcct gcggttatgt
     3121 gtttcttatt cgttaaaaca aatagccatt atcaaaggaa ttgattataa aacagtatca
     3181 tatcacaaaa taagagccct aaataaactt aacataaaag gtactgttga gttgtttata
     3241 gcactctgtg aatgggataa acattatttt aaactccaat cttgcataag agaaagttga
     3301 tatgtcatta gtaatgatat aatagtaaaa tcataataac tgtagcgctg atatcgttgc
     3361 tctctgcatg caccagagaa aattcattaa aggatactca gaataaaata agtggcgaat
     3421 ctcaagcgat agtagatgca agacagttct ttagcgaaca cccggaatat atatcatcag
     3481 cagaactaga gcagaagcta tatcgcgaat ttgcgcaggt tactactgtt ccagcttata
     3541 aagagatgag tatgtatcaa ttgcttgtca tttcgcaaga tcgtttaaca cattaaataa
     3601 gaatctacac gctttttgcg tgtagattct tataaatttc cgactatgat agatgtttaa
     3661 tttttttaat tattgtcttt attctcactt tttgtgtctt caccttcttt gaatttatct
     3721 tctgagggga gcagttcatc tggaacaggt tgtccagcat tctccacatc ttcaagccac
     3781 agcagaagac gcaagatctc atctatattt tcgaagctaa cataatcgta gcgacgatgg
     3841 gtagcataaa tttttcgtgc taatttttta tctgtaataa ttggtattcc gatttccttt
     3901 gcatatttcc ttacggctaa tgctacctca ttagtttctc tcacagaaat caatggtata
     3961 ggtgaaagat gtggcttaaa gtatatccct atggcaatgt gcgtagggtt ggcaatcatc
     4021 agacggctat tactgacatc agatttcaat tgctctgaca gaatttcttg atggcgttct
     4081 ctgcgtttag atttaatttc tggacttcct tcttgttcct tgtattctct tttaacttct
     4141 tgtttatcca ttttcatatc tttcataaat aaaaaatatt cagcgataaa atcaaaaatt
     4201 aagacaatta tcatactgcc gaggcaatac agtatgagaa ggaatagcat ctctccccaa
     4261 tctgataata aagaaatgat atctccatca agagttttaa aaagcagtga tttatggtta
     4321 ctccaaaata atttgatcgc caatgcaaaa aaaataatat aaagtattgc tttaacaaat
     4381 tcttttacgg tttttaagcc aaatatacgt tttaagccat ttactggatt taatgaatca
     4441 aacttaaact taatagcttc agttgctaat tgcattttac tttgaaacca tgaaacaagt
     4501 attgttgtaa acatacaaac cagcaaaaaa ggaatgatcg ttttcaacca acctatcccc
     4561 atagctttaa aatagtccca aatatccggt ttagcgttat gatcaaggat atattcaaga
     4621 atcgacataa tgtgatgcac atcaaataca tatccgagat ataaagtacc cacaagcatt
     4681 attacacaga ctgttaagtc tctacttttt agaatttgac cttttttaga agcatcctgg
     4741 agtttctttt gtgttggctt ttcagtttta tttgccgtga aacactctat ttatcaatgt
     4801 ataattgcaa ttgttctggg aaaaaggata acggcataac tcgttcagcc agtattgggc
     4861 caaaataaat aattaatatt aaaaatgcca gcgcactttt gacagtcagt gagatggcaa
     4921 aagcatttag ttgtgaagca taacgtgcca gcaatcccag gacagcttca ccgcccagca
     4981 taaccgcaat cacggggctt gcgt
//
LOCUS       DACAOP010000185         4944 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.186, whole genome shotgun sequence.
ACCESSION   DACAOP010000185 DACAOP010000000
VERSION     DACAOP010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4944
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.186"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..633)
                     /locus_tag="IT892_004399"
     CDS             complement(<1..633)
                     /locus_tag="IT892_004399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfK family protein"
                     /protein_id="HAP3137522.1"
                     /translation="MSGFFQRLFGKDNKPAIARGPLGLHLNSGFTLDTLAFRLLEDEL
                     LIALPGEEFTVAAVSRIDLGGGSQIFRYYTSGDEFLQINTTGGEDIDDIDDIKLFVYE
                     ESYGISKESHWREAINAKAMGAITLNWQEKRWQRFFNSEEPGNIELVYMLEKVENQNH
                     AKWEVHNFSMGYQRQVTEDTYEYLLLNGEESFNDLGEPEWIFSRALGVDIP"
     gene            complement(683..1381)
                     /locus_tag="IT892_004400"
                     /pseudo
     CDS             complement(683..1381)
                     /locus_tag="IT892_004400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418603.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PspA/IM30 family protein"
     gene            complement(1400..1801)
                     /locus_tag="IT892_004401"
                     /pseudo
     CDS             complement(1400..1801)
                     /locus_tag="IT892_004401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313184.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2170 family protein"
     gene            complement(1992..3587)
                     /locus_tag="IT892_004402"
     CDS             complement(1992..3587)
                     /locus_tag="IT892_004402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAP3137523.1"
                     /translation="MQKILRIDSNDNLIVALKDLHAGESYSWDDDNITLVTDVKAKHK
                     FATQDIPLDGIVSMYGTPVGKATRPIVKGEAITVDNIRHYAAPVTLEDVEPYHWQAPD
                     VSEWSTRTFKGYVRDDGRVGTASYWLVFPLVFCENRNVSKLTNALNDALGYTNNSLKK
                     FALNLTSGSDELIETARMFPHIEGVRCITVTSGCGGATSDCETMCDVLAAYADHPNVI
                     GMTVFSLGCEKAQQKMFKDALARRNPEFDKPALYFLQQEWDSEERMMQTALQQTFEAM
                     KAVKPTERVEVPLSCLKVGMKCGGSDGFSGISGNPAMGLVSDWLTTLGGASGLAEFPE
                     LCGAEGDMVKRCINLEDKKKFLNLMQGYEKTANFFDTTIADNPSFGNIADGLITDAIK
                     STGAAKKGGRAPIVSVCDYAEPMPDSGLSLVCTPGNDVDAVTGLVAAGCNVVIFSTGL
                     GTPTGNPIVPVLKISTNSTIARRLSDMIDFDCGPVIDGTPLEDVSRELFEKVIETASK
                     DYVVKADKLEQFDFMLWKRSLDL"
     gene            complement(3621..4922)
                     /locus_tag="IT892_004403"
     CDS             complement(3621..4922)
                     /locus_tag="IT892_004403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3137524.1"
                     /translation="MANITQYDNPLLNSAIQKSWKRLVPLMFIMYFVAFIDRVNVGFA
                     KDAMKLDIGLSESAFALGAGIFFAAYALFGIPANLILNKIGAQKWLSITTAIWGLLSA
                     MMGFVTGETQFIILRFLLGLGEAGFYPGILLLASIYFPNKVRGSVVGIFVLGVPLALT
                     LGSPISGALLELHGWMGRPGWFWMFVIEGLPALVLGIFTWFYLDDNPTKARFLTQEEK
                     DALNKQLESERQKTETSSVISALKNAKVWHLALIYGTIQISVYGLMFFLPSQVASLMG
                     ESLGFKQSLVAAIPWACSACGVYYIPRIADRNPSRRVAISVMCMLAAAVGLALSAFAG
                     PVVAIGALCLSAVGFLSVQPIFWTFPPQLLTGPALAAGIGFCTTMGAFCSFLAPLIRV
                     EVDRAMDSSIAGLMALSVITIGCALLIGLLQKSQQAAKAYS"
BASE COUNT         1374 a         1257 c         1008 g         1305 t
ORIGIN      
        1 cgggatatcg acacccagcg cgcgcgaaaa tatccactcc ggctcgccga gatcgttaaa
       61 tgattcctca ccatttaaca gcaaatattc gtaagtatct tcggtcactt gccgttggta
      121 gcccatgcta aaattatgga cctcccattt ggcatggttt tgattttcta ctttttccag
      181 catgtagacg agttcgatat ttcccggttc ttcactgtta aaaaatcgct gccagcgttt
      241 ttcctgccag tttaaggtta tagcccccat cgctttggcg ttgatcgcct cgcgccagtg
      301 actctcttta ctgataccgt agctctcttc atagacaaag agcttgatat catcaatgtc
      361 atcaatatct tcgccgccgg tggtattgat ttgcagaaat tcatcgcccg aagtgtagta
      421 gcggaaaatc tggctaccgc cgcccagatc gatgcggctg acggcggcta ccgtaaattc
      481 ctcacccggc agcgcaatca gcaattcatc ttccagcaaa cgaaatgcta acgtgtcgag
      541 cgtaaagcca ctattgagat gaagtcccag aggaccgcga gcgatagcag gcttattatc
      601 cttgccaaac agacgctgga aaaaaccaga catattttat ccttaaaata gttgccagcc
      661 ttttagcgag gctggcaaaa aattactcgc cctgttggcg ttgcagtctt gctaatacat
      721 cctgggcgct acttttattg ctaccgccaa ttccggcttc cgccagcttt tcatcaagat
      781 cgcgaccgtc tgcgactttt tccaactgtg cggcagcatc caggcgagcc tgacgttcgg
      841 cctgacgcgt ttgcaggcgt tttaaggatt ctgccgctgt cgaaacgctg gaagatgcgc
      901 caacggtaga ggtcgttaca gcctgttgtg cacgctgcat ggcttcagta gctttaacga
      961 cttccatttg ctgctcaaac tgagcgatac gctgcgctgt cgctgtaact gctttttcca
     1021 cgccatcacg agagacttcc agattcgaca acacttgctc ttcagcggta atgagattct
     1081 caaggcgcgc gatttcttca gcaacttcgt taatcaacga cggattaacg ttcttgctta
     1141 acgcttacag cgcacgagct tccagactgg ctttgcgctc acgtaaatct ttcagcttat
     1201 cgtgacttaa tttcacccgc gccagcagat caacgcgaga ttttccggct ttatcgagtt
     1261 cagctttagc gtcacgaata tgctgttcca gcatgcgcac gccctgggtt tcttcaatgg
     1321 attcttccgc ttgggagata aacgatttcc ccagcgtaaa taaacttttt aaaattccca
     1381 taaatacccg tccttgtaat tagtgtgaat attcttctgt aatttcagcc agatccaatg
     1441 cgttatctac cagcgaggtt atctcaagca ggatatcttc aagagaagat ttaagcgata
     1501 acgcaccgaa aacaatgtaa tactcttcat gttgcacgct ggagatccct accgatgaca
     1561 acggcatcat cttctgattt cttaataaga aggtattaaa ttcatctgga ttgctgatac
     1621 tactcaccgg acaaataaag gtttcgataa tcatttggcg ggaagtaaaa agaatattga
     1681 tttacaaatc gccataatca ttcattttaa taattaatgc gttatagcta tttgttacat
     1741 caatattttg ttcaggtaca gtttgcagcg ccgtcgccag cgccaacgga ttccatgtca
     1801 tatattattc catataaatt aagtttaaat attaataaaa tgaatatttg cagtacgtaa
     1861 ttatcttacc agctatagac aaaaaaaaac catccaaatc tggatggcta tttagaagaa
     1921 ccaaaaattt aacgctatgc atacgataaa aaatgcgcca gtctacatac gctgacgcta
     1981 atgattagtc actacaagtc taacgaccgc ttccacaaca taaagtcaaa ctgttcaagt
     2041 ttgtctgcct tcacgacgta gtccttactg gcagtttcaa taactttttc aaataattct
     2101 ctactcacat cttccagcgg agtgccgtca atcactgggc cacagtcgaa atcaatcatg
     2161 tcagacaatc gtctggcaat cgtgctgttg gtggatattt ttaacaccgg aacaatcggg
     2221 ttaccggtgg gcgtaccaag acccgtcgag aagataacca cattacatcc tgctgctacc
     2281 aatccggtta ccgcgtccac gtcattgccc ggagtacaca ccaacgataa tccactatcg
     2341 ggcatcggtt cagcgtaatc gcatacactc acaattggcg ctcgcccgcc ttttttcgct
     2401 gctccggtag attttattgc gtcagtaatc aacccatccg cgatgttgcc aaaacttggg
     2461 ttatccgcaa tggtggtatc gaaaaagttc gctgtctttt cgtagccttg cattagattg
     2521 aggaactttt ttttatcctc aagattaata caacgcttaa ccatatcacc ttctgcccca
     2581 cataattctg gaaattctgc taacccggaa gcgccaccaa gcgttgtcaa ccagtcagaa
     2641 accagcccca ttgcagggtt gccggagata ccagaaaaac catcggaacc accacacttc
     2701 atccccactt tgagacagga aagagggacc tctactcttt ctgtcggctt caccgctttc
     2761 attgcctcga aagtctgctg taaagcggtc tgcatcatcc gctcttcgct gtcccactcc
     2821 tgttggagaa agtagagcgc aggtttatca aattcaggat tacgtctcgc cagcgcatcc
     2881 ttaaacattt tctgctgcgc tttttcacat cctaaactga ataccgtcat accgattaca
     2941 ttcggatggt cagcataagc agctaataca tcgcacatag tttcacagtc tgaagttgca
     3001 ccaccacaac cactggtgac cgtaatacag cgaacacctt caatatgcgg gaacattctc
     3061 gcggtttcga tcagttcatc gctaccggac gtcagattaa gagcaaactt tttcagtgag
     3121 ttattggtat aacccaaagc atcattcaaa gcattggtta acttactgac attacggttc
     3181 tcgcaaaata ccaatggaaa gactaaccag taactggcag tacccactct gccatcgtca
     3241 cggacataac ctttaaaagt gcgggtgctc cattcagaga catccggtgc ctgccagtgg
     3301 tagggttcaa catcctccag tgtgacagga gctgcatagt ggcgaatatt atcaacggta
     3361 atcgcttctc ccttaacgat gggacgcgtg gccttgccaa ctggcgtacc gtacatcgaa
     3421 acaatgccat ccagaggaat atcttgcgtc gcaaacttat gtttagcctt aacatcagtt
     3481 actaacgtta tgttgtcgtc atcccacgag tacgattctc cagcgtgcag gtctttcaac
     3541 gcgacaatga gattatcgtt actgtcgata cgtaatattt tttgcataat catattcttc
     3601 cagtcagatg ttcaatctta ttaactgtat gcttttgctg cctgttggct cttttgcagc
     3661 aatccaatca ataatgcgca gccgatagta attacagaca acgccatcaa tccggcgatg
     3721 ctgctatcca ttgcccgatc aacctcaaca cggataagag gagcaaggaa cgagcagaaa
     3781 gcgcccatcg tggtgcaaaa accgatcccc gcagccagtg ccggaccagt aagaagttgt
     3841 ggagggaaag tccagaatat tggctgtact gagaggaaac caaccgcact taaacaaagt
     3901 gcaccaatcg ccacaacagg ccccgcaaat gcggaaaggg caaggccgac agcagcagcc
     3961 aacatacaca taaccgaaat ggccacacgc cgggaaggat tgcggtcagc aattcgcgga
     4021 atgtaataga cgccacaagc agagcacgcc catggtattg ccgcgactaa tgactgctta
     4081 aagccaaggc tttctcccat cagcgatgca acctgtgacg gaaggaaaaa cattaaacca
     4141 tatactgata tctggatggt gccgtagatt aatgccagat gccaaacttt ggcatttttc
     4201 aatgctgaaa tcactgaact ggtttctgtt ttctgtcgtt cagattccag ttgcttattc
     4261 aaagcgtctt tttcttcctg ggtaagaaat cgcgctttcg tcggattatc atcaaggtag
     4321 aaccaggtaa agataccaag cactaatgcc ggcaatccct caatgacaaa catccagaac
     4381 catcctggac gtcccatcca gccatgtagt tcaagtaaag ctcccgatat tggcgaaccg
     4441 agcgttaacg ccagcggcac ccccaacaca aatattccca cgaccgatcc gcgaaccttg
     4501 ttaggaaaat aaatggatgc gagcagtaaa attccgggat agaaccccgc ctcgcccagc
     4561 cctaacagaa agcgcaaaat aataaattgc gtttcaccgg tgacaaatcc catcattgcc
     4621 gagagaaggc cccaaattgc agttgtaata cttaaccact tttgtgcgcc gattttattg
     4681 aggatcaggt tagctggaat gccgaaaagt gcataggcag cgaaaaatat tcctgcaccg
     4741 agagcgaatg ccgactctga taatccaata tccagtttca ttgcatcttt ggcaaagcca
     4801 acatttaccc gatcaataaa ggcaacaaaa tacattatga acattaaggg tactaaacgt
     4861 ttccacgatt tttgaattgc ggaattcaac agcggattat cgtattgggt tatattagcc
     4921 ataaataaat ccttagttct gttg
//
LOCUS       DACAOP010000186         4900 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.187, whole genome shotgun sequence.
ACCESSION   DACAOP010000186 DACAOP010000000
VERSION     DACAOP010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4900
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.187"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..308
                     /locus_tag="IT892_004404"
     CDS             <1..308
                     /locus_tag="IT892_004404"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137525.1"
                     /translation="KKYIKRTPEQRKAYLEAQLNSVNAKLNKQKRKEANAKRRETDHL
                     KYTFAGDILKVMGCDVREVDLALVLGAVYYATNKNANSKNVELYRKAGLEILKENKK"
     gene            1187..2632
                     /locus_tag="IT892_004405"
     CDS             1187..2632
                     /locus_tag="IT892_004405"
                     /inference="COORDINATES: protein motif:HMM:NF013603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HAP3137526.1"
                     /translation="MFTGTSVFNKNRSVNRPDNLKEFASVNGERITERKKETFNIALS
                     MKDKGEDLQDETLTKRAERSLKCSSFRYIATVNGQAQTLYTHRCKGRHCQECQRIKAY
                     IWQKKTESIFPKLEENYLNAKYLFATFTIKNPKITDLRVVLSVMNKAANRLFKMKKYK
                     DFILGGIRSTEITRGKSGADECHPHFHFLLMVKGNYGKKYYVNQEDWGKDWGDCLAYE
                     CDRAGYPYNPIDYPRGFPIVDVVRAMDKEKKIEITNKNIKNSGEAIINYVLKYSVKGS
                     DILDHKKGKNDDWFFEFDKQIKGCRMITPVGVFKKYLSEIKKDPFDYDIEKAKIEERL
                     GEGYQVNKAIFKKGDYKLENKKDNEGYLLEALEAKAYNYQQLYLTMYSDYIKFYNDTN
                     REISKLEDKLFNEDNMLIESKIGRLLLIQEDRKKRINNTIESLKRVGYLKEEKGLYYD
                     EWGSLWATFEIEKPTIEIVEINDFADMFEVW"
     gene            2632..2778
                     /locus_tag="IT892_004406"
     CDS             2632..2778
                     /locus_tag="IT892_004406"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137527.1"
                     /translation="MKKKQKPKKRNRNKKSKFFKMLMASVREAVEISKGNIEPARITI
                     LNKE"
     gene            complement(2813..4111)
                     /locus_tag="IT892_004407"
     CDS             complement(2813..4111)
                     /locus_tag="IT892_004407"
                     /inference="COORDINATES: protein motif:HMM:NF015354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HAP3137528.1"
                     /translation="MAIYYFDVSNVSRSSGKKSASSVAASAYQNRARYTDERTGTTYD
                     YTKKGGLYYSGILAPENAPESLTASPLTLWNTVEATEKRKDARLAKDFKISLPIELSP
                     EQNKALILDFAKQAFVSKGMIVDLAIHDIDTQPHSHIKTTTRELTPEGFGGKVREWDK
                     KETTLYWRELWAKVANEHLLKAGHDITISHLTLKEQMKEALEEMDKTTDLEEKIKLAS
                     KAIELNRPAMKTISKKDWDDPKFQAIRKQEQEAKKQILKKAKNFRIKNIRELREIQKE
                     LDKKFRPSKIYKSISEAIRNLNNKITDSKLNNILNDKLDKLNETIKSVPDKIKHSIEK
                     RKIKKENKKRERMNKEEEKIFRETHKMDEFGNIYKKGDSKKWNKKNNELIKQQTASNK
                     AKAEEERERKKLEDEANRLAEKNNISPNDFKQKKKKGLNV"
     gene            4374..4676
                     /locus_tag="IT892_004408"
     CDS             4374..4676
                     /locus_tag="IT892_004408"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137529.1"
                     /translation="MSHDFYIERKKDKKKAVFNGYAEGVFYKHFHCEKYNAIWSGSND
                     GQDVSKRGTENALRKILESEEIKNYPDPDRINEIREFYENVVLKSNDQDKFYVHFL"
BASE COUNT         1584 a          725 c          947 g         1644 t
ORIGIN      
        1 aaaaaaaata tattaaaagg actcctgagc aaagaaaggc atatttagaa gcccagctta
       61 atagtgtaaa tgcaaaacta aataagcaga aaagaaaaga ggctaatgct aagagaagag
      121 aaacggatca tttaaaatat acttttgcag gtgatattct aaaagttatg gggtgcgacg
      181 ttcgggaagt tgatctggct ttggtgcttg gtgctgttta ctatgctaca aataaaaacg
      241 caaattctaa aaatgttgaa ctatatagaa aagcaggact ggaaatttta aaagaaaata
      301 aaaaataagt ttgacaataa tataattaga atatattaat atataagtcg gtatgtttat
      361 ttaattcctt gacaaattta atatatataa cggcaaattg ccccatttat ggggatattg
      421 gagaggctaa cttaggttag cctttcgtcc tttctgatac cgttcaccag tgccgaaccg
      481 tcaagcagaa tgtcgggggg tcccctctgg ggttccgtca ttgtgcttgt acggctccct
      541 ggtcaataca acacttggca aaggtggaag gtgaacaaag tgagccttct acctgataag
      601 ccgcccttaa atggttttaa gttgtattaa atgacatttg ataatacaac ttgccccggt
      661 aggggttgcc tttggtttta ggggtttggt ttgaggttgc cgaaggcgac ccctcccctt
      721 gtttagtaag aaacaaatgg aggcaaaact tggcttctaa aactccccta caagccccgt
      781 cattactggc tttaacccca tttttttagc agttttcaag gggggtaaat agcacttttt
      841 gctaaagaat tttagaacaa aaaataatca atcccccaga tatgggacag caccttcaag
      901 atcgccagaa aacaccccaa aaaatgggac gacacctttt aaaactatcc gacaaacgga
      961 agatttggga cggaacattt agaacaccgg ttttttggtg tgaaaaatgg gacgggtcta
     1021 accgtaacgg cataaaaaca cggaaaaaat gggacggtat cgacttttgg cggtggggga
     1081 agttttggag gtagatctga taagtgcttg actggtttga caaaaagaaa aaaccccgta
     1141 gagttgaact tgcgaaggta tcaaacaata cggggtattt cttaatatgt ttacagggac
     1201 aagtgtattt aataaaaata ggtctgtcaa tagaccggat aatttaaaag agtttgccag
     1261 tgtaaacggt gaacgaataa cagaaagaaa aaaagagacc tttaatattg ctttgtctat
     1321 gaaagacaaa ggcgaagatc tacaagacga gacattaact aaaagggctg aaaggtcttt
     1381 aaagtgttct tcttttcgtt atatcgccac agttaacgga caggctcaaa ccttatatac
     1441 tcaccgttgc aaaggtcgcc actgtcagga atgccaaaga attaaggctt atatctggca
     1501 gaaaaaaaca gagtctattt ttccaaaact ggaagaaaac tatctaaatg caaaatattt
     1561 atttgcgaca tttacgatta aaaacccaaa aataacagat ctaagggttg ttttatctgt
     1621 aatgaataaa gcagcaaata gactttttaa aatgaaaaaa tataaagatt ttattcttgg
     1681 aggtatccgt tcgacggaga tcacaagggg aaaatctggg gcagacgaat gtcacccaca
     1741 cttccatttt ttgttaatgg taaaaggtaa ttacggcaaa aaatactatg taaatcaaga
     1801 agattggggg aaagattggg gggattgcct ggcttatgag tgtgataggg cagggtatcc
     1861 gtataatcca atcgactatc ctcgtgggtt cccaatcgtg gacgtcgtta gagctatgga
     1921 caaagaaaag aaaatagaaa taacgaataa gaatattaaa aattcgggtg aagcgattat
     1981 aaattatgtt ctaaaatatt ccgtcaaggg cagtgatatt ttagaccata aaaagggtaa
     2041 aaatgacgat tggttttttg aatttgataa gcaaattaaa ggttgtcgaa tgataacacc
     2101 agttggagtt tttaaaaaat atctaagcga aattaaaaaa gatccgtttg attatgatat
     2161 tgaaaaagca aaaatagagg aaagattagg agaaggctat caggttaata aagctatatt
     2221 taaaaaaggc gattataaac ttgaaaataa aaaagataat gaaggttatt tattagaggc
     2281 attggaagca aaagcatata attatcaaca attatattta actatgtata gcgattatat
     2341 taaattctac aacgacacta acagggaaat atctaaatta gaagataagt tatttaatga
     2401 agataatatg ttgatcgagt ctaaaatagg aagattatta ttaattcagg aagatagaaa
     2461 aaaacgaatt aataacacta ttgaaagttt aaaaagggtc ggctatctta aagaagaaaa
     2521 agggctttac tatgacgaat ggggatcgct ttgggcaaca tttgaaattg aaaaacctac
     2581 tattgagata gtggagatta acgattttgc tgatatgttt gaggtgtggt aatgaaaaag
     2641 aaacagaagc ccaaaaaaag aaatcgtaat aaaaagagta aattctttaa aatgctaatg
     2701 gcttcggttc gtgaagccgt tgaaatttca aaaggaaata ttgagccagc aaggatcaca
     2761 attttaaata aagagtagta tagtatattg tagtatatag tagtatatag tcctatacat
     2821 ttaacccttt ctttttcttt tgcttaaagt cattaggtga aatattattt ttttcagcca
     2881 atctgttagc ctcatcctct aattttttcc tctctctttc ttcttcggct tttgctttat
     2941 tactggctgt ttgctgttta attaattcat tatttttctt attccatttt ttggaatctc
     3001 cttttttata aatatttccg aactcatcca ttttgtgagt ttctctaaat attttttcct
     3061 cttccttatt cattctttct cttttcttgt tttctttttt tatttttctc ttctctatgg
     3121 aatgctttat tttatcagga actgatttta ttgtttcgtt taatttatct aatttgtcat
     3181 ttagaatatt atttaatttt gagtcggtga ttttattatt taaatttcta attgcctcgg
     3241 aaattgattt atatattttt gacggtctaa attttttatc caattctttt tgtatttctc
     3301 ttaattctct tatgttttta attctaaaat ttttagcctt ttttaatatt tgttttttag
     3361 cctcctgttc ctgttttctt attgcctgaa atttgggatc gtcccagtct ttcttgctga
     3421 tagttttcat tgctggtcta tttaattcga tagccttaga agcaagtttt attttttcct
     3481 ccaggtcggt tgttttgtcc atttcctcca gtgcttcttt catttgttct tttaatgtca
     3541 aatggctgat agttatgtcg tgtccagctt ttaataaatg ttcgttagcc acttttgccc
     3601 ataattccct ccagtataaa gtcgtttctt ttttatccca ttccctaact tttccaccaa
     3661 atccctccgg tgttaattct ctggtagttg tttttatgtg gctatgtggt tgggtgtcta
     3721 tatcgtgaat agccagatct acaatcatcc cttttgatac gaaagcctgt tttgcaaagt
     3781 ctaaaattaa ggctttgttc tgttctgggg atagctctat gggtagggaa attttaaagt
     3841 ctttggcaag cctggcatcc ttcctcttct cagtagcctc tacggtgttc catagggtca
     3901 acggtgaagc tgtgaggctc tcaggtgcat tctccggggc taaaatgcct gagtagtata
     3961 aacccccctt cttggtgtag tcgtatgttg taccggttcg ttcgtctgtg tatctggctc
     4021 tgttttggta tgcagaagca gcaacagacg aagccgattt tttgcctgag cttctactca
     4081 cattggaaac atcaaaataa tatatagcca tattgtaaaa cctccacttt tctaattttt
     4141 ttggggtttg gtttttgctt ttcttttttc ccgtttacgg gaaaaaaccc tgtcattgcg
     4201 ttagcaatgc gtagaagggc ttcaagtaat ttttattttt tcgtaaactc aaaataaaaa
     4261 actttcagaa cggcaaaaat gcttttcctt attttagata taacataaat ttgactaaag
     4321 taaattacgg aggtatatgc ttaataatta caaaaatata tatggaggtt tttatgtcgc
     4381 atgattttta tatcgaaaga aaaaaagata aaaagaaggc tgtttttaat ggatatgctg
     4441 agggagtatt ttataagcat tttcattgtg aaaaatataa tgctatttgg tctggtagta
     4501 atgacggaca agatgtttct aaaagaggta ctgaaaatgc acttcgtaaa atattagagt
     4561 cggaagaaat taagaattac ccagatcctg accgtattaa tgaaattaga gaattttatg
     4621 aaaatgtagt cttgaaatct aatgatcaag ataaattcta tgtgcatttt ttgtaggggt
     4681 agattatgat ttttataggt tttattttag gtctggggtt tgtccttata atgggtttat
     4741 tgtatgaatt ttttaataat tatcaaaaac tcaaaggaaa aacggacggc ttagaagctc
     4801 ttgttttaag gttggaatat aaattagatt atgtaattaa tgaatgtaat aagaggggtt
     4861 ttgatttaga ggaggagata tattatgacg acgacgactg
//
LOCUS       DACAOP010000187         4716 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.188, whole genome shotgun sequence.
ACCESSION   DACAOP010000187 DACAOP010000000
VERSION     DACAOP010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4716
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.188"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            1188..1904
                     /gene="nanC"
                     /locus_tag="IT892_004409"
     CDS             1188..1904
                     /gene="nanC"
                     /locus_tag="IT892_004409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313297.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminic acid outer membrane channel
                     NanC"
                     /protein_id="HAP3137530.1"
                     /translation="MKKAKILSGVLLLCFSSPLISQAATLDVRGGYRSGSHAYETRLK
                     VSEGWQNGWWASMESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGMLTHF
                     SSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAYRQQDLSGDMSRDNVHRWDGYVTYH
                     INSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDRQGV
                     YNGRDNLSENSYRIGVSFKL"
     gene            1924..3030
                     /locus_tag="IT892_004410"
     CDS             1924..3030
                     /locus_tag="IT892_004410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418730.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HAP3137531.1"
                     /translation="MNKTITALAIIMASFAANASVLPETPVPFKSGTGAIDNDTVYIG
                     LGSAGTAWYKLDTQAKDKKWTALAAFPGGPRDQATSAFIDGNLYVFGGIGKNSEGLTQ
                     VFNDVHKYNPKTNSWVKLMSHAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNE
                     AGKDSTTIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNK
                     GDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLAPVASPDGVAGGFAGMSNDSLIF
                     AGGAGFKGSRENYQNGKNYAHEGLKKSYSADIHLWHNGKWDKSGELSQGRAYGVSLPW
                     NNSLLIIGGETAGGKAVTDSVLISVKDNKVTVQN"
     gene            3095..4075
                     /locus_tag="IT892_004411"
     CDS             3095..4075
                     /locus_tag="IT892_004411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HAP3137532.1"
                     /translation="MNAIISPDYYYVLTVAGQSNAMAYGEGLPLPDKEDAPHPRIKQL
                     ARFAHTHPGGPSCHFNDIIPLTHCPHDVQDMQGYHHPLATNHQTQYGTVGQALHIARK
                     LLPFIPDNAGVLIVPCCRGGSAFTAGSEGTYSERHGASHDACRWGTDTPLYQDLVSRT
                     RAALAKNPQNKFLGVCWMQGEFDLMTSDYASHPQHFNHMVDAFRRDLKQYHSQLNKIT
                     DAPWFCGDTTWYWKENFPHAYEAIYGNYQNNVLANIIFVDFQQQGARGLTNAPDEDPD
                     DLSTGYYGSAYRSPENWTTALRSSHFSAAARRGIISDRFVEAILQFWRER"
     gene            complement(4083..4205)
                     /locus_tag="IT892_004412"
     CDS             complement(4083..4205)
                     /locus_tag="IT892_004412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012139841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP3137533.1"
                     /translation="MISYVFLLPVCPNCHAMLHRRKPPFTPEELKALMDANKSN"
     gene            4301..4716
                     /locus_tag="IT892_004413"
                     /pseudo
     CDS             4301..4716
                     /locus_tag="IT892_004413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004186812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
BASE COUNT         1419 a          978 c         1046 g         1273 t
ORIGIN      
        1 ctaatcttat ctatatatca tgtgatatgt tctgtaacaa gtaaaatcaa cataaaaaat
       61 tcagcaaaat ttaatattcg ctcaactagc cgtctcacat atgacattat tagtcaactc
      121 catttgccac aaaatggcta tttcatggaa cgcagtaatt tcttagtggc tattatcatg
      181 ctaattctta ggtccctagc tattattcct ggctggttcg tcagtttaga ccatgagatt
      241 gttacattcc tttttatcat ggagatatgg gggaaagcag gaaacgattt tttcatctgc
      301 atccgttggt aaatatggct ttggtcacta cgacttaaac cttcctcaat cacagctgtt
      361 cgccgggcga tacggcaaac aaactaagtg aggcatcacc ctgaaaacac caacatcaac
      421 aagcctctcc agatcggctt caggagtgac cagttacaag ccacaaacca ggaaacatat
      481 ttcatgatga gaattatgct aagcctgatg gcgggtaaac acttattttc accaagctca
      541 ctgagttagc ttacaaagct tcccttattt agactctaaa taaatttttt ataaaacaga
      601 tatttaaaag aatatcttta gtttttgaag accaccgcaa gtgttcgtct ggcttcacat
      661 ggcatcttcc tcttagaaaa agatcgacat attttgtgac acgaattgca aatctggttt
      721 tgttgtatgg attgcgtgat ttttgatctg gtataacagg tataaaggtg caccgcgata
      781 gacaatgaga cagggcatct tgcaatctat ggcaaacatc acttcagttc tttctcatcg
      841 ggtgatgaaa acgcacttca gtctgaaagg aatatgaaaa tgagatcaac aaacactcta
      901 ttttatgact ctgggtaaaa tggattgagt aagtgatata gcttacgaac attcaaatca
      961 attaaacatc agaagagatt ttatactcag gtatttaatc tggctctctg tttatttaaa
     1021 taatgtgaaa agagaatttt cacaggagac cttatacaaa aaatataaaa taagctaccc
     1081 attgccaaag acactataag cctggcaaaa aatattacac aacataaatg ctaattgttt
     1141 atgcgggctt tgtattgctt tctgtatcct acaaatgagt gaaatttatg aaaaaggcta
     1201 aaatactttc tggcgtatta ttactgtgct tttcgtcacc attaatttct caggctgcga
     1261 cactggacgt acgtggtgga tatcgtagcg gaagccatgc ctatgagact cgactcaaag
     1321 tcagtgaggg atggcaaaat ggatggtggg caagcatgga aagtaatacc tggaatacca
     1381 ttcatgataa taaaaaggaa aatgccgcac tcaatgatgt tcaggttgaa gttaattacg
     1441 cgattaaact tgatgatcaa tggacggtgc gcccgggaat gttaacgcat tttagcagca
     1501 acggcacccg ctacggaccc tacgtaaaac tgtcctggga cgcgacaaaa gatcttaatt
     1561 ttggcattcg ctatcgttac gactggaaag cttaccgaca acaagactta tccggtgata
     1621 tgtctcgtga taacgttcat cgttgggatg gatatgtcac ttaccatatt aatagtgatt
     1681 tcaccttcgc atggcaaacg acgctataca gcaaacagaa cgattatcgc tatgcaaacc
     1741 ataagaaatg ggcgacggaa aatgcatttg ttctacaata ccatatgacg cccgatatta
     1801 cgccatacat agaatatgac taccttgacc gtcagggtgt ttacaacggc agagataatt
     1861 tatcggaaaa cagttatcgc attggtgtat catttaaact gtagtagaca ggagacagtc
     1921 acaatgaata aaacaataac ggcgcttgct atcataatgg cttcatttgc cgcaaacgcg
     1981 tctgtattac cggaaactcc tgtgccattt aaaagtggta ccggagcaat tgataacgac
     2041 actgtctaca ttggtttagg tagcgcaggt acagcatggt acaagctgga tacacaggcc
     2101 aaagataaaa aatggacagc gttagctgca ttccctggtg gaccgagaga tcaagcaacc
     2161 tctgcattta ttgatggtaa tctgtatgtg tttggcggca ttggcaaaaa cagcgagggc
     2221 ttgactcagg tatttaatga cgtacacaaa tacaacccca aaaccaatag ctgggttaaa
     2281 ttgatgtcgc acgcgccgat gggcatggcg ggccatgtga cttttgtaca caacggcaag
     2341 gcttatgtta ctggcggtgt taaccagaat atcttcaatg gctattttga agatctcaac
     2401 gaagctggaa aagattcaac cactatagat aaaatcaacg cccactattt tgacaaaaaa
     2461 gcagaagatt atttcttcaa taagtttctg ttgtcttttg atccctctac acagcaatgg
     2521 agttacgctg gcgaatctcc ctggtacgga acggctggtg cggcggttgt gaataaaggt
     2581 gataaaacct ggcttattaa tggcgaagcc aaaccaggat tgcgaacgga tgccgtattt
     2641 gaacttgatt tcaccggtaa taatttaaaa tggaataagc ttgctcccgt cgcatcacca
     2701 gatggcgtcg ctggcggttt tgcaggcatg agcaatgact cacttatatt tgccggaggg
     2761 gccggattca aaggttcacg agaaaattac cagaacggta agaactatgc gcatgaaggc
     2821 ctgaaaaaat catatagcgc tgatattcat ctttggcata acgggaaatg ggataaatcg
     2881 ggcgaattat cgcaaggtcg ggcctacgga gtatcattgc cctggaataa tagtttatta
     2941 attattggcg gtgaaactgc aggcggcaaa gcggtgacgg attcagtttt aatttctgtg
     3001 aaggataata aagtcacagt acaaaactaa cgcttcaggg ccccggtaaa ggggccttgc
     3061 tatcaatttg tcatttgtat tacgcgaaaa ttatatgaac gcaataatat cgcccgatta
     3121 ttactatgtt cttaccgttg ctggtcagtc taatgccatg gcgtatggcg aaggactacc
     3181 attaccggac aaggaagatg cgcctcatcc cagaattaaa caattagcga gatttgcgca
     3241 tacacatccc ggaggcccgt catgtcactt taacgacatt attccactga ctcactgccc
     3301 acacgatgtt caggatatgc agggttatca ccatcctctg gcaacgaatc atcaaacaca
     3361 gtacggcacc gttggccagg cactacatat agcacggaaa ttactgccct ttattcctga
     3421 taatgcaggg gttctcatcg ttccgtgttg ccgtggcgga tcggctttta ccgcgggcag
     3481 cgaagggaca tattcagaac ggcacggagc cagccatgat gcttgtcgtt ggggaacgga
     3541 tactccgcta taccaggatt tagtcagcag aacgcgagcc gcactggcaa aaaatccgca
     3601 gaacaaattc ctcggcgtat gctggatgca aggcgaattt gacttaatga ccagtgacta
     3661 cgcgtcacac cctcaacact ttaatcatat ggttgacgcc tttcgtaggg atctaaaaca
     3721 ataccattct cagcttaata aaattactga cgcgccgtgg ttttgcggcg ataccacctg
     3781 gtactggaaa gaaaatttcc ctcatgcgta tgaagctatt tatggcaatt atcaaaataa
     3841 tgttctagcc aatattattt tcgtcgactt ccagcaacaa ggtgcaagag gactgacgaa
     3901 cgcgcctgat gaagatccgg acgatttaag cacgggatat tacggttcag cgtaccggtc
     3961 accggagaac tggacgacgg cactgcgaag cagtcatttc agcgcggcag cccgtcgagg
     4021 gattatttct gacaggtttg tagaagcaat tttgcagttt tggcgcgaaa ggtgagcgtt
     4081 cattaatttg atttattcgc atccatcagc gcttttaact cctccggcgt aaacggtggt
     4141 ttgcgtcggt gcaacatcgc atggcaatta gggcacacag gaagtaaaaa aacatatgag
     4201 atcaaggtaa tatatcttcg cttgcaggct tgaaccgcag aaaatttgcg agcatgatcg
     4261 caattatttc actgccaggg atatcaatgg cttccagtaa atcgctgacg agcctttttt
     4321 tgctctccag caaatccgta agcagcgtga cccattattt cgcaaacatg tattacgcgc
     4381 ttataactac cagtgcgcaa tatgtagctt taatatttgt tacggcaact ccaccgtctc
     4441 actggaagcg acacatataa aatggaaaca acatggtggc ccttgtgaaa ttcccaatgg
     4501 cctggcgctt tgcgcgatac atcataaagc ctttgataaa ggaacgattg gcctggatga
     4561 aaatatgcgg gtactggtat tggatgcggt aaacggcgga gagatcattg agaggtcatt
     4621 ctgggatttt gacggaaaaa ttattgcgtt gccacaggtg cgtaaaaatt acccttttga
     4681 gggggttgta gagtggcatc ggaaagagtt ttttag
//
LOCUS       DACAOP010000188         4467 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.189, whole genome shotgun sequence.
ACCESSION   DACAOP010000188 DACAOP010000000
VERSION     DACAOP010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4467
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.189"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(253..339)
                     /locus_tag="IT892_004414"
     tRNA            complement(253..339)
                     /locus_tag="IT892_004414"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(303..305),aa:Leu,seq:taa)
     gene            complement(352..425)
                     /locus_tag="IT892_004415"
     tRNA            complement(352..425)
                     /locus_tag="IT892_004415"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(391..393),aa:Cys,seq:gca)
     gene            complement(480..555)
                     /locus_tag="IT892_004416"
     tRNA            complement(480..555)
                     /locus_tag="IT892_004416"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(520..522),aa:Gly,seq:gcc)
     gene            complement(707..1255)
                     /gene="pgsA"
                     /locus_tag="IT892_004417"
     CDS             complement(707..1255)
                     /gene="pgsA"
                     /locus_tag="IT892_004417"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAP3137534.1"
                     /translation="MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAV
                     TDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIARE
                     IIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
                     AVLTLWSMLQYLSAARADLLDQ"
     gene            complement(1312..3144)
                     /gene="uvrC"
                     /locus_tag="IT892_004418"
     CDS             complement(1312..3144)
                     /gene="uvrC"
                     /locus_tag="IT892_004418"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310678.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAP3137535.1"
                     /translation="MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLS
                     SYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSY
                     PFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
                     NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETAS
                     QNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKV
                     LGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLS
                     ELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEV
                     KRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRY
                     GKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLET
                     LFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGP
                     KRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH"
     gene            complement(3141..3797)
                     /gene="uvrY"
                     /locus_tag="IT892_004419"
     CDS             complement(3141..3797)
                     /gene="uvrY"
                     /locus_tag="IT892_004419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrY/SirA/GacA family response regulator
                     transcription factor"
                     /protein_id="HAP3137536.1"
                     /translation="MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCR
                     TNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYL
                     SKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
                     ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ
                     "
     gene            4093..4269
                     /locus_tag="IT892_004420"
     CDS             4093..4269
                     /locus_tag="IT892_004420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137537.1"
                     /translation="MIKIFIGHYINVFYSTADIALKKQPLLFLAKLMVYSAALTFFTA
                     NFHCNMTRKINEYA"
     gene            4256..>4467
                     /locus_tag="IT892_004421"
     CDS             4256..>4467
                     /locus_tag="IT892_004421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein"
                     /protein_id="HAP3137538.1"
                     /translation="MSTPDFSTAENNQELANEVSCLKAMLTLMLQAMGQADAGRVMLK
                     MEKQLALIEDETQAAVFSKTVKQIKQA"
BASE COUNT         1169 a         1168 c         1018 g         1112 t
ORIGIN      
        1 gttgagtggg aagatcccag aaaaaatttt gatttaacca aggccctagt tcaacatgcg
       61 aaatgcagat tagttgcagg agagttctgc ttcaccctta gagcttcaac agacgtgcac
      121 tatcattgtt tctgcatatc gccacatcat cgccacttta ccgccattgc acaaaataca
      181 aatacaaaaa aaccacccga aggtggtttc acgacactgc ttattgcttt gattttattc
      241 ttatctttcc catggtaccc ggagcgggac ttgaacccgc acagcgcgaa cgccgaggga
      301 ttttaaatcc cttgtgtcta ccgattccac catccgggct cgggaagaaa gtggaggcgc
      361 gttccggagt cgaaccggac tagacggatt tgcaatccgc tacataaccg ctttgttaac
      421 gcgccaaatt cttcaggcct ttcaaccaga catccgcttg aggccgatgt cttttaaact
      481 ggagcgggaa acgagactcg aactcgcgac cccgaccttg gcaaggtcgt gctctaccaa
      541 ctgagctatt cccgcattca tcaagcaatc agttaatcac ttgattttat tatcgtctgg
      601 caatcagtgc cgccgttcga tgcgttgcat tctacttacc tggcgcgatg agtcaacgat
      661 atttttcacc acttttgatc gtttgctgaa aattacgccg aaacgatcac tgatcaagca
      721 aatctgcacg cgcagcgctc aaatattgca acattgacca cagagtcagt accgcagcca
      781 caaagaaaag tgcaataccg gcgtactcaa cccaaatgtt cggacgccac agcagccagg
      841 ccaacgccac catctgggca gtggttttca ctttcccaat ccaggagacg gccacgctac
      901 tgcgtttacc caactccgcc atccattcgc gtagcgcaga aataataatt tcacgggcga
      961 tcatcgttgc cgccggtaat gtcacccacc agctgtgata atgctcggtt accagcacca
     1021 tggcgatagc cacgagaact ttatctgcga cagggtcaag gaaagcacca aaccgggtac
     1081 tctggttcca gcggcgtgcc agaaaaccat cgaaccagtc agtcaccgcc gcgacgcaga
     1141 aaatgagcgc ggcggcaaac ggcgaccagg tgacaggcag ataaaagacc aatacaaaga
     1201 atgggataag gatgacacgg aacagtgtaa gcaacgtagg gatattaaat tgcataatga
     1261 cgggtaacta tctgttgtca gtaagattac ccctatgttg ctacagagac atcaatgttt
     1321 caacgaccag aagatctttt ctgccagacc ttgcgaaata cccggcactt ttgcaatttc
     1381 ctcgacgctg gcgttacgta aaccttgcaa accgcccata tatttcaaca acatttgccg
     1441 acgttttggc ccgacgcctt caatggtttc cagggaactg gtatttttga ctttcgcccg
     1501 ttttttacgg tgcccgccaa tcgcgtgatc atgtgattca tcgcgaatat gctggataac
     1561 atgcagcgcg ggtgaatctg gcggcaaact aaatccctca ccttccggct caaagaacag
     1621 cgtttccagt ccagccttac gatctgctcc tttggcaacg ccaagtagca gcggatgatt
     1681 tttatcccat gagacatcca gttcggcgaa gacatttttc gcctgcgcaa gctggccttt
     1741 gccgccgtcg ataaggatca catccgggat cttactgtcg tcaatggctt taccataacg
     1801 ccgacgcagc acctgattca tcgccgcata atcatcgccc ggcgtgatgc cagtaatgtt
     1861 atagcgccga tactccgcac gcagcgggcc gttagcatca aacaccacac aggaagcgac
     1921 ggtttgttca cccatggtat ggctgatgtc aaagcactcc atccgcttca cttccggtaa
     1981 tttcaacacg ctggcaagcg cggtcagtcg ctggtgaacg gtagattgct gcgaaagttt
     2041 gctggttaag gccgtcgccg cattggtgcg cgcgagtttc agataacgcg cccgatcgcc
     2101 gcgaggtttg gtttgaacat taatcttgcg tcccgccagt tctgaaaggg aatcggcgag
     2161 cagcgtttta tcgctaagat taaaatcgag caggatctca cccggtaagg tgcgcatctg
     2221 gctgccttgt aaatagaact gacctacgaa ggtttccacc acctcgctca gttccgtacc
     2281 gcccggcact ttcgggaaat agctgcggct gccgagcact ttaccctgac gaatgaacaa
     2341 tacgtggaca caagccatgc ccgcatcgaa cgccacacca ataacgtcaa ggtcgtcgcc
     2401 ggtattggac acaaactgtt tttcggtgac gcgtcgcacc gcctgaattt ggtcgcgaat
     2461 acgtgccgct tcttcaaact ccagattctg gctggcagtt tccatacgac taatgagttg
     2521 cgtaagcacc tgatcatctt taccagacaa aaacaggcgc acatactcga cctgctgagc
     2581 gtattcttct tcactcacca gtccttcaac gcacggtccc agacagcgcc ctatctgata
     2641 ttgcagacac ggacgcgagc gattgcgata aacactattt tcgcactggc gaatggggaa
     2701 aatcttttgc agtagcgcca gagtttcacg tacggcatag ccattcggga acgggccgaa
     2761 atattcacct ttggcatgct tcgcaccacg atgcatcgcc agacgcgggt gggtatcgcc
     2821 actcaggaag ataaaaggat aagatttatc atcgcgtagc aaaacgttgt aacgcggctg
     2881 atagagtttg atgtagttgt gttccagcaa cagcgcttcg gtttctgtat gcgtaaccgt
     2941 tacatcaatt tgctggatct gggcgaccag cgcttcggtt ttgcgcgaag cgaggttgct
     3001 gcggaaatag ctggaaagcc gttttttcag gtctttcgct ttgccgacat agataaccgt
     3061 accaccagca tcgtacatgc gataaacgcc tggctggctg gttacggttt ttaaaaacgc
     3121 ttttgcgtca aactgatcac tcactgactt gataatgtct ccgcattaca cagaccatgg
     3181 cgaattgcca ggtgagtcag ctcaacatcg ccatgaatgt ttagtttact gaacatacga
     3241 tagcggtagc tgttcaccgt tttcggactg agattgagct gttctgagat ctcattgacc
     3301 ttctggccct tagtgatcat cagcataatc tgcaattcac gttcagacaa actggcaaat
     3361 gggctttctg ttttttctgg ttcgatctgg cttaacgcca tttgttgagc gatatcagaa
     3421 gcaatgtaac gctgcccaga atagacagaa cgaatcgcac tcacgacttc ctgcggagcc
     3481 gcgcctttgc tgaggtagcc cgcagcacct gcctgcatga ctttcgctgg taaagggttt
     3541 tctgtatgga ccgtaagcat gatgatttta acatcagctg tggaacgcgc gattttacgc
     3601 gtcgcctcaa gaccgccaat gcccggcata ctcatgtcca ttagcaccac gtcaacggca
     3661 tttgtccggc accacttaac ggcgtcttca ccgcacgatg cctctccgac gacttttata
     3721 ccctttatat cttccagaat gcgtcgtatc cctgcgcgca ccagttcgtg gtcatcaaca
     3781 agtagaacgt tgatcaaagg aatatctcca gaaataggga taacgctact gatagttagt
     3841 cattcgtata ttagcggttt ttattgcaac tttgaaacgt taaaaatggt gggtattcga
     3901 tttttctctc gtttttgtca attcgattgt ccacagttat ggtcacgccc gtcaccaacg
     3961 gcttaccgga tcgtttcaca gtaagcccta cgatgaaatg tgacaaaaat tgactttatt
     4021 cagcaaaaat gaaaatcagc ccgctgaata tgtaacatta attaacccga acaatacggg
     4081 caaaaaacat tcatgataaa aatatttatt ggtcattata ttaacgtatt ttatagcact
     4141 gccgatatcg cgctcaaaaa acaaccactg ctatttttag caaagcttat ggtatactcc
     4201 gccgccttaa catttttcac cgcaaatttt cattgcaaca tgacgaggaa aataaatgag
     4261 tacgcctgat ttttctactg ccgagaataa tcaagaactg gcaaatgaag tctcctgcct
     4321 gaaagcgatg ctgacgctga tgctgcaggc gatgggacaa gctgacgcgg gccgcgtgat
     4381 gttaaagatg gaaaaacagc ttgcgctgat cgaagacgaa acccaggctg cagtattttc
     4441 caaaacggtt aagcaaatta aacaagc
//
LOCUS       DACAOP010000189         4437 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.190, whole genome shotgun sequence.
ACCESSION   DACAOP010000189 DACAOP010000000
VERSION     DACAOP010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4437
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.190"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            71..166
                     /locus_tag="IT892_004422"
     CDS             71..166
                     /locus_tag="IT892_004422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAP3137539.1"
                     /translation="MLVFQMRYQMRYVDKTSTVLKQTKKSDYADK"
     gene            292..1029
                     /gene="erm(B)"
                     /locus_tag="IT892_004423"
     CDS             292..1029
                     /gene="erm(B)"
                     /locus_tag="IT892_004423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP3137540.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPRVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1659..2108
                     /locus_tag="IT892_004424"
     CDS             1659..2108
                     /locus_tag="IT892_004424"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137541.1"
                     /translation="MTTILSDYNKSILIELLNTNRQIIVVHGDDIDDYYTDSCYDIIF
                     IDYYDDDDFTYNGQEIWRGDSIYLVKSYQDEIQNRIEKGQELIFVNKENDISFSESIL
                     TYYHLFDYAGKTFEIDGQIIDEQTKVFAAPERRCACRTCWKVPARKT"
     gene            2261..2410
                     /locus_tag="IT892_004425"
                     /pseudo
     CDS             2261..2410
                     /locus_tag="IT892_004425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005920153.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
     gene            2637..4169
                     /locus_tag="IT892_004426"
     CDS             2637..4169
                     /locus_tag="IT892_004426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019726358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP3137542.1"
                     /translation="MPRLATSRRQAAGCAPLPSAHTGSRYARHAPERTLLYALVEAHY
                     PDFIARIEAEGRSLPGYVREAFDAYLRCGVLEHGFLRVVCEHCRAERLVAFSCKKRGF
                     CPSCGARRMAESARHLVEEVFGPRPVRQWVLSFPYPLRFLFASKPEAIGPVLGIVQRV
                     IAGWLADQAGIDRASAQCGAVTLIQRFGSALNLNIHFHMLWLDGVYVEATELPRRELR
                     LHRARAPTTAQLTQLAAAIAHRVCRHLTRKGWLEGEGESAFLADSAAGDDSMDGLRMS
                     SITYRIATGRDAGCKVVTLQTLPGDAGSLEGEAGKVGGFSLHAGVAAEAHESHKLEKL
                     CRYITRPAISEKRLSIALQGRVRYQLKTPWRNGTTHVEWDPVDFIAKLAALVPPPRAH
                     LTRFHGVFAPNAALRAQLTPSGRGRRHDAAVEPADASANDAPRSPEEKRRSMSWAQRL
                     KRVFSIDVTACVHCSGTVRIVASIEEPAAIRAILGHFVKQGAREEAHYRPAARAPPVQ
                     AA"
BASE COUNT         1170 a         1144 c         1135 g          988 t
ORIGIN      
        1 aattttgtat aataggaatt gaagttaaat tagatgctaa aaatttgtaa ttaagaagga
       61 gggattcgtc atgttggtat tccaaatgcg ttatcaaatg cgttatgtag ataaaacatc
      121 tactgttttg aaacagacta aaaaaagtga ttacgcagat aaataaatac gttagattaa
      181 ttcctaccag tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc
      241 gtttaacttc tgtatttgtt tatagatgta atcacttcag gagtaaatta catgaacaaa
      301 aatataaaat attctcaaaa ctttttaacg agtgaaaaag tactcaacca aataataaaa
      361 caattgaatt taaaagaaac cgataccgtt tacgaaattg gaacaggtaa agggcattta
      421 acgacgaaac tggctaaaat aagtaaacag gtaacgtcta ttgaattaga cagtcatcta
      481 ttcaacttat cgtcagaaaa attaaaactg aatactcgtg tcactttaat tcaccaagat
      541 attctacagt ttcaattccc taacaaacag aggtataaaa ttgttgggaa tattccttac
      601 catttaagca cacaaattat taaaaaagtg gtttttgaaa gccatgcgtc tgacatctat
      661 ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac actagggttg
      721 ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga atgctttcat
      781 cctaaaccaa gagtaaacag tgtcttaata aaacttaccc gccataccac agatgttcca
      841 gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg agaatatcgt
      901 caactgttta ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt aaacaattta
      961 agtaccgtta cttatgagca agtattgtct atttttaata gttatctatt atttaacggg
     1021 aggaaataat tctatgagtc gcttttgtaa atttggaaag ttacacgtta ctaaagggaa
     1081 tgtagataaa ttattaggta tactactgac agcttccaag gagctaaaga ggtccctaga
     1141 ctagcaagaa gtacacaaga agccttaaag attatagaaa agcttttcca tgaaatgctt
     1201 aacattattt aatgttaaca tgtggctttg tggtaactac cacgagtggt aacttgtaac
     1261 atgaaaaaag ttacaagtta caagtggttt atttacgaac ataaaggcta ggaaagcact
     1321 tgataagtat atcaagtgct ttttttccgt tcgattttac tatccaagat accgcttgac
     1381 gtacctaata ttttagtgtg ctaagggctt tgctttttct ggttatagtt cgttcaaaaa
     1441 agaccgcaag ggtaaatgca cgatcataga tcgcccttgc agctttttaa tctctccact
     1501 tttttataac caagcaaacc accaagcaca ctgaaaaaat aattaggaac taaagcgaag
     1561 tgcgtatctt ggataaatct tcactcgatt ttaaaagatt aagcacccag ccaaagcgcc
     1621 taaaaaaata atttttttaa agaaaggaag taatttaaat gactacaatt ttaagcgact
     1681 acaataaatc tatcctaatt gaattactaa acaccaatcg ccaaattatc gtcgttcatg
     1741 gcgacgatat tgatgattat tacacagatt cttgctatga cattatcttt attgattact
     1801 atgatgatga tgatttcact tataacggac aggaaatatg gcgtggcgat agcatttatc
     1861 ttgtaaaaag ttatcaagat gaaattcaaa accgtataga aaaaggacaa gagctgatat
     1921 ttgttaataa agaaaatgat atatcatttt cagaatctat tttaacttat taccatctat
     1981 ttgattatgc tggtaaaacg tttgaaatag acggtcaaat cattgatgaa caaacaaaag
     2041 tttttgccgc acccgagcgc cgctgcgcat gtcgcacgtg ctggaaggtg ccagccagga
     2101 agacctgaac ctttaccgcg cggaagtgga gcgcgaccag gcctatggca actggcgcga
     2161 tttcttcctg aacaagaagg gcagcgtcac atccgtgagc ggtgatgcca acctcgacca
     2221 gatcgcggac gtgtcgtacc tgctggatac cttctttgcc aaggtcaccc gcaccgcgtt
     2281 gcagaacgcc gcctccatcg cgggcctgat gatcaccacc gaagccatgg tggccgaggc
     2341 cccgaagaag gacgagccgg cgatgccgcc gggcggcggc atgggtggca tgggcggcat
     2401 ggatttctga tgcggttggc ccggtcgtca gggaaccgga ccgcgccagc gcggtccgat
     2461 cccggcaacg acccgacatc aaggccccaa ggacggggcc ggagcccggc agcgatgccg
     2521 ggctttttgt tgtgcccgcg ccgcggcaat gtctgacgcg aagatcagaa cgcaccgata
     2581 cgaacgtgcg aacacaggtg caaccctgag cagccgtccc cgcaccggag cgctgcgtgc
     2641 cgcgcctcgc cacatcccgg cggcaagccg cgggatgcgc gccactgccg tccgcccaca
     2701 ccggttcgcg gtacgcgcgc cacgcgcccg agcgcacgct gctgtacgcg ttggtagagg
     2761 cgcactaccc ggacttcatt gcacggatcg aagcggaggg ccgctcgctg cccgggtatg
     2821 tccgcgaggc gttcgatgcc tacctgcgtt gcggcgtgct cgagcacggc ttcctgcggg
     2881 tggtgtgcga gcactgccgt gcagagaggc tggtggcctt ctcctgcaag aagcgcgggt
     2941 tctgcccgag ttgcggcgcg cgacgcatgg ccgagagtgc gcggcacctg gtcgaggagg
     3001 tgttcggccc gcggcctgtg cggcaatggg tgctgagctt tccgtacccc ttgcgtttcc
     3061 tgttcgccag caagccagaa gccattggcc cggtgctggg catcgtgcag cgcgtgatcg
     3121 ccggctggtt ggccgatcaa gccggcatcg accgcgccag cgcccagtgc ggcgcggtga
     3181 cgctgatcca gcgtttcggc agcgcgctga acctgaacat ccacttccac atgctgtggc
     3241 tcgacggcgt gtacgtggaa gccaccgagc tgccgcggcg cgaactgcgc ctgcaccgcg
     3301 cccgtgcgcc caccaccgcg cagttgaccc agctggcagc tgccatcgcg caccgggtgt
     3361 gtcggcacct gacgcgcaaa ggctggctcg aaggggaggg cgaatcggcc ttcctggcag
     3421 acagcgctgc aggcgacgac agcatggatg ggctgcggat gagttcgatc acctaccgca
     3481 tcgccaccgg ccgcgacgct ggctgcaagg tcgtcacgct gcaaacgctg cccggtgacg
     3541 ccggttcgct ggagggcgaa gccggcaagg tcggcggctt ctcactgcat gccggcgtgg
     3601 cggccgaagc acacgaaagc cacaagctgg aaaagctgtg ccgctacatc acgcgcccgg
     3661 cgatcagcga gaagcggctg tcgatagcgc tccagggcag ggtgcgttac cagctcaaga
     3721 ccccgtggcg caatggcacc acgcatgtgg aatgggatcc ggtggatttc atcgccaagc
     3781 tggcggcgct ggtcccgcca ccgcgcgccc acctgacccg cttccacggg gtgtttgccc
     3841 cgaacgccgc cctgcgcgca cagctgacgc catcggggcg cggcaggcgg catgacgccg
     3901 ctgtggagcc ggcggacgca agcgcgaacg acgcgccgcg cagccccgag gagaagcgcc
     3961 gttcgatgag ctgggcgcaa cgcctcaagc gggtcttttc catcgacgtc accgcctgcg
     4021 tccactgcag tggcaccgtg cggatcgtcg ccagcatcga ggaacctgcc gccatccgcg
     4081 ccatccttgg ccacttcgtg aagcagggcg cgcgggaaga agcgcactac aggcccgcag
     4141 cgcgcgcacc gccagtgcaa gccgcgtgac gatctgccgg ctgcacagcc gacggcgaaa
     4201 ccggaatccg agccgatgcg gccacgatcc gcagggcggc gctcggcccg ctgtcgggaa
     4261 tcagcgaagc atggctgctg acaacgccgc tgcgtggccc cgcgatgccg aaatcccact
     4321 cacagacgtc cgatccgtgc ccaaaacggg gcttgcgcga ccgccgccta cccagcagac
     4381 tgcccgaaaa gggcgtttga acttcctata cgctgatagt gcattatctt aaaattt
//
LOCUS       DACAOP010000190         4361 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.191, whole genome shotgun sequence.
ACCESSION   DACAOP010000190 DACAOP010000000
VERSION     DACAOP010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4361
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.191"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..623
                     /locus_tag="IT892_004427"
     CDS             <1..623
                     /locus_tag="IT892_004427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS600 family transposase"
                     /protein_id="HAP3137543.1"
                     /translation="ARLRKELRLRCKQKRKFRATTNSNHNLPVAPNLLNQTFAPTAPN
                     QVWVADLTYVATQEGWLYLAGIKDVYTCEIVGYAMGERMTKELTGKALFMALRSQRPP
                     AGLIHHSDRGSQYCAYDYRVIQEQFGLKTSMSRKGNCYDNAPMESFWGTLKNESLSHY
                     RFNNRDEAISVIREYIEIFYNRQRRHSRLGNISPAAFREKYHQMAA"
     gene            777..2774
                     /locus_tag="IT892_004428"
     CDS             777..2774
                     /locus_tag="IT892_004428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004119118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HAP3137544.1"
                     /translation="MSENDTIPKKSTSQINKAVFFTSALLIFLLVAFAAVFPDVADKN
                     FKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSWFAML
                     FSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAIVA
                     LILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQ
                     VNAGLNHLFGVPINETVQVILIVVITGLATISVVSGLDKGIRILSELNLGLALLLLAL
                     VLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPKSSNWLGGWTLLYWGWWLSWS
                     PFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNQGATDLANTV
                     QQDVALALFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLASGGVANTPVW
                     QRIFWASLMGIVAIALLLAGGLSALQTVTIASALPFSVILLISIYGLLKALRRDLTKR
                     ESLSMATIAPTAARNPIPWQRRLRNIAYLPKRSLVKRFMDDVIQPAMTLVQEELNKQG
                     TISHISDAVDDRIRLEVDLGNELNFIYEVRLRGYISPTFALAAMDNDEQQTEQHRYYR
                     AEVYLKEGGQNYDVMGWNQEQLINDILDQYEKHLHFLHLVR"
     gene            2837..4114
                     /locus_tag="IT892_004429"
     CDS             2837..4114
                     /locus_tag="IT892_004429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2254 domain-containing protein"
                     /protein_id="HAP3137545.1"
                     /translation="MISRWKWMLKQTIKKLWFRATLFAIVAIITALLSILFKSMIPES
                     VSVKVGAEAVDNILNILASSMLAVTTFSLSIMVTAYGSATTNVTPRATRLVVEDVTTQ
                     NVLATFIGSFLFSLVGIIALNMGAYGERGRVILFIVTLVVIALILITLLRWIQHLTSL
                     GRVGETTAQVEQAAIETFIARARNPCLGGYPWLENNEQPKGTVAVYPKKIGYVEYIDM
                     VKLSKLLTNDPRHVYLVAQPGSFIHPSMPVLYLSQGQESSINTDLLETIIVSDARSFA
                     QDPRFCLSVMAEIACRALSPAVNDPGTAIDVIGRGVRILSTYAQNKSDEIEVKYPSVH
                     VAPLQNNDLLEDFFSPVARDGASMREIQIRVLKGLSMLSKGWPEIFAEAAHTLAFETL
                     EHATRADHIDSDRYLIKSTYYNLFSGEYSNKKT"
BASE COUNT         1079 a         1007 c         1100 g         1175 t
ORIGIN      
        1 tggcacgtct tcgtaaggag ctaaggctac gctgtaagca gaaacgcaag ttcagagcga
       61 ctacgaactc gaaccacaat ctgccagttg cgccaaatct gctgaaccag acgttcgctc
      121 ctacagcacc aaatcaggtc tgggtggcgg acctgacgta tgttgccaca caggagggat
      181 ggttgtacct cgctggcatc aaagatgttt atacgtgcga aattgtcggc tacgccatgg
      241 gagagcgcat gacaaaagag ctgacaggta aagccctgtt tatggcgctc aggagccagc
      301 gcccacctgc cgggctaatc caccactctg atcgaggttc acagtactgc gcatacgatt
      361 accgggtcat acaggagcag tttggtctga aaacatcaat gtcgcgtaaa ggtaactgtt
      421 acgacaacgc tccgatggaa agcttctggg gaacgctgaa aaatgagagc ctgagccact
      481 atcgttttaa taaccgggat gaagccatct cagtaatacg ggaatacatt gagattttct
      541 acaatcgtca gcgtcgtcac tctcgtctgg ggaatatctc cccggcagcc ttcagggaaa
      601 aatatcatca gatggctgct taaaaaaaga acaaatggta gtgtccgcta ttgccagtac
      661 acctcaacat tccaccatgc attacgatta acgccgcata gccagttgaa ctttgctact
      721 ttgtgagagg tagtaccttc tatccagtgc gaatttaatt aatggaataa atgattatga
      781 gtgaaaatga tacaatccca aagaagtcta caagtcagat taacaaagcg gtattcttta
      841 catctgcttt gctaattttc cttcttgtcg cctttgccgc cgtattcccg gatgtcgccg
      901 acaaaaattt taaactactt cagcaacaaa tcttcacgaa tgccagctgg ttctacatcc
      961 ttgctgtggc cctgatttta ctgagtgtca cgttccttgg actctcacgc tacggtgata
     1021 tcaagctggg cccggaccat gcgcagcctg atttcagcta ccactcctgg tttgcgatgc
     1081 ttttttcggc agggatgggg atcggcctga tgttctttgg cgttgccgaa cctgtaatgc
     1141 attatctttc gccacccgtt ggcactccag aaaccgttgc ggcagctaag gaagcaatgc
     1201 gtctgacctt tttccactgg ggactgcacg catgggcaat ttatgccatt gtggcgctga
     1261 ttctggcgtt cttcagttac cgtcacggtc tgcctttaac tctgcgctcc gcactctatc
     1321 ccattattgg cgatcgcata tacggacctg taggacatgc ggttgatatt ttcgctgtta
     1381 taggcacggt ctttggcgtt gcgacatcac tgggttacgg tgttttgcag gtgaatgccg
     1441 gtttgaacca tcttttcggg gtgcccatca atgaaacggt gcaggtaatt ctgatcgtgg
     1501 tcatcacggg gttagcgacg atttcagtgg tgtccggtct ggataaggga atacgtatcc
     1561 tgtctgaact caatctgggt ctggctttgt tgctcctggc gctggtcctg tgtctgggac
     1621 caaccgtgct tctgctgaag tcatttgtgg aaaatacggg cggttatctt tcggaactgg
     1681 tgagtaaaac gttcaacctt tacgcgtatg agcccaagtc gagcaactgg ctggggggct
     1741 ggacattact gtactgggga tggtggcttt catggtcgcc gtttgtgggg atgttcatcg
     1801 cacgggtctc ccgcgggcga accattcgcg agtttgtcac cggcgtgctg tttgttcccg
     1861 cgggttttac gctaatgtgg atgacggtgt ttggtaacag cgcgatctat ctcattatga
     1921 accagggggc cacagacctc gccaatactg ttcagcagga tgtggcgctg gccctgttta
     1981 atttcctgga gcatttcccg ttctcttctg tgctgtcatt cattgcaatg gcgatggtca
     2041 tcgtcttctt tgtaacgtct gctgattcgg gggcaatggt tgtggatact ctggcatcag
     2101 gtggagtggc aaacacaccc gtctggcagc gaatattctg ggcctcgctc atgggcattg
     2161 ttgcaattgc gcttctcctt gccggagggc taagtgcgct gcaaacggtg acaatagcga
     2221 gtgcattgcc cttctcagtg atcttactaa tatctatata cggactttta aaagctttgc
     2281 gccgggattt gaccaagcgt gaaagcctga gcatggcgac aattgctcct acggctgcac
     2341 gtaacccaat tccttggcag agaaggttac gcaatatcgc gtatctgccg aagcgatctc
     2401 ttgtgaaacg ttttatggac gacgttatcc agcctgccat gacgctggtt caggaggaac
     2461 tgaacaagca ggggacgata agccacatta gtgatgcagt cgacgatcgt attcgtcttg
     2521 aagtcgattt gggcaacgag ctgaatttta tatatgaagt gaggcttcgc gggtatatct
     2581 caccgacctt cgcgctcgcc gcaatggata atgatgagca gcagactgaa caacatcgat
     2641 attatcgcgc tgaggtttat ctcaaagaag gcggtcaaaa ttatgatgtg atgggctgga
     2701 accaggaaca gctgattaat gacatactgg accagtacga aaaacacctg cacttcctgc
     2761 acctggttcg ttaatagcaa catgccgtcc tgggggcggc aattattatc ccggccgcaa
     2821 tatgagggaa tgcagaatga tttcacgctg gaaatggatg ctgaagcaga caattaaaaa
     2881 actatggttc agggcaacgt tattcgcaat tgtcgcgata ataacggccc ttttatcaat
     2941 tctttttaaa tcaatgatac ctgagtcggt ttccgtgaag gttggtgcgg aagcagtcga
     3001 taacattctg aacatactgg catcgagtat gctggcagtg accacatttt cgctgagtat
     3061 catggtcaca gcctacggtt cagccactac taatgtgact cccagagcta cgcgtttagt
     3121 tgttgaagac gtcaccacac aaaatgtact ggccaccttc atcggttctt ttctcttcag
     3181 tctggtaggg attattgccc tcaatatggg agcttatgga gaaaggggga gagtcatttt
     3241 attcattgtc acactggttg tcattgcctt aatcctcatc acattgcttc gctggataca
     3301 gcatttgacc tctctgggga gggttggtga gacaacggca caagtagaac aggcggccat
     3361 cgaaacattt attgcgagag caagaaatcc ctgtctcggt ggatatccat ggcttgagaa
     3421 caatgaacag ccgaaaggaa cggttgcagt ttatccgaag aagattggct atgttgaata
     3481 tattgatatg gtgaaactta gcaagctgct gaccaatgat ccccgtcatg tatacctcgt
     3541 ggcgcagcca ggcagtttca tacatccgtc catgccagtt ttgtacctga gtcagggcca
     3601 ggagtcgtca atcaacaccg atttacttga gacgattatt gtctcggatg cacgttcatt
     3661 tgctcaggat cctcgatttt gtcttagcgt catggccgaa atagcctgcc gggccctttc
     3721 ccctgcagtg aacgatcctg gaaccgccat tgatgtcatt ggcagaggtg ttcgtatact
     3781 ttccacttac gcgcagaata aatctgatga aatagaagtg aaatatcctt cagtacatgt
     3841 tgcaccactt cagaataacg atctactgga agactttttc tcacctgtcg cgcgcgatgg
     3901 tgccagtatg agggagattc agataagagt ccttaaagga ctgtcgatgc tgagtaaagg
     3961 ttggcctgag atatttgctg aagccgcaca taccctggca tttgaaacat tagagcatgc
     4021 aactcgtgct gaccatatag attctgatag atatctaata aaatcaactt attataattt
     4081 atttagtggc gaatattcta ataaaaaaac atagctgcag agcaagcaat tcggttgttg
     4141 gcaagtcaag ggcaaagcat tcgcgtgaga atgggcgtat gctttgtgcc aaaagcaaac
     4201 gttgctaatt ctgcactgtt cagcgatggc gcagtagaga caggcactgc cactgtccag
     4261 tcggcaaaag cgaacacttt gccactgcgg ggataaactg attgaagctc tcgcgcaaaa
     4321 tcacttattc ttttgcgtta ataaaatgta ggagatgggt c
//
LOCUS       DACAOP010000191         4306 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.192, whole genome shotgun sequence.
ACCESSION   DACAOP010000191 DACAOP010000000
VERSION     DACAOP010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4306
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.192"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..844
                     /locus_tag="IT892_004430"
     CDS             <1..844
                     /locus_tag="IT892_004430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HAP3137546.1"
                     /translation="PLDDSGQIDLTGLEKHMARLSDSGINGILLSGTIGEFATMSVRE
                     RAMLILEARKMSDLPLIAHISSTVEEDMLYLADAAYDSGYDAVMVLPQYYYAQTSRQL
                     LSYFRSLDRKLAGDWFIYNFPARTGCDVDAHLVRMLAESCPRFIGIKDTVDCASHTRA
                     IVNAVTPLRKDFAVFAGFDEYFVPNLMNGGAGVLSGLNNVVPELFAQIMRAYRAGDLN
                     EVAGLHKEIGRLSGIYAIGDDFVSTIKTAISRKYGYMTPVSRNHNGQLTADQADCLDK
                     LFGL"
     gene            869..1249
                     /locus_tag="IT892_004431"
     CDS             869..1249
                     /locus_tag="IT892_004431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001403366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HAP3137547.1"
                     /translation="MKKDIIYTTGAPAPGGALSQAVKAGETIYLAGQVGFDPHTMQVV
                     STDFDEQARQAFKNLLSVAEAAGGSDRDIVKLNAYLTDVNMFPRFNAIMSEYFSPPYP
                     ARATLGIAALPQGAVIEIEAIMVL"
     gene            1282..2247
                     /gene="kdgT"
                     /locus_tag="IT892_004432"
     CDS             1282..2247
                     /gene="kdgT"
                     /locus_tag="IT892_004432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate transporter"
                     /protein_id="HAP3137548.1"
                     /translation="MNIKKTVEKIPGGMMLAPLFLGAVLHTFWPGTGKYFGSFTNGMI
                     TGVVPILAVWLFCMGASIKISATGTVLKKSGTLVATKIATAWVCAFVFAQLLPEGGMV
                     KTGFFAGLSVLAIVAAMDMTNAGLYASLMQEYGTKEEAGASVLISLESGPLMTMIILG
                     SAGQATFEPEHLAGVLIPFLVGFLLGNLDPELRELFSRATKSLIPFFAFALGNTINLG
                     VIIDTGLLGILMALAVIVITGVPLIIMDIMLGKGRGTAGIAASSTAGAAVATPLLVAE
                     IAPDFAEAAPAATTLVASCVVITAIVVPVITALWAKHGASRVRAT"
     gene            complement(2293..3045)
                     /locus_tag="IT892_004433"
     CDS             complement(2293..3045)
                     /locus_tag="IT892_004433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAP3137549.1"
                     /translation="MIATKTPAIDKAARIFHFIAGKGSATYSEIHQNVGLPQSTTSAL
                     LASLTTHAFLRQKNGRYYLGLIFYELGNKAIQDFDFRELAEESLVFLRDQTRLACHLG
                     VLDGSTGIYLAKKESQNAIIVRSWTGKRLSLHSSSLGKVLLAWLPEDHIDALLPTEHL
                     PAFTARTITTRKALKAELEVVRLQGWAFDNQEDVDDVTCIAAPVFNSDQAVVAAISIS
                     GVRFQMPEEKIPEYANAVMKAAGMMSEKLCGI"
     gene            3650..3934
                     /locus_tag="IT892_004434"
     CDS             3650..3934
                     /locus_tag="IT892_004434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HAP3137550.1"
                     /translation="MQMKNNAAQATKVITAHVPLPMADKVDQMAARLERSRGWVIKQA
                     LSAWLAQEEERNRLTLEALDDVTSGQVIDHQAVQAWSDSLSTDNPLPVPR"
     gene            3934..4209
                     /locus_tag="IT892_004435"
     CDS             3934..4209
                     /locus_tag="IT892_004435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP3137551.1"
                     /translation="MELKWTSKALSDLSRLFDFLVLASKPAAARTVQSLTQAPVILLT
                     HPRMGEQLFQFEPREVRRIFAGEYEIRYEINGQTIYVLRLWHTRENR"
BASE COUNT         1044 a         1098 c         1105 g         1059 t
ORIGIN      
        1 tcctctggat gacagcggtc agatagacct cacggggctg gaaaaacata tggcacgcct
       61 ttctgattcc ggcatcaacg gcattctgct atcaggtacc atcggggaat ttgccacaat
      121 gagcgtccgc gaacgggcaa tgctcatcct ggaagcccgg aaaatgagtg acctcccttt
      181 gattgcccat atttcatcta ccgttgaaga ggacatgctt tatctggctg atgccgccta
      241 tgacagtggc tatgacgcag taatggtact gccacagtat tactacgccc agacatcccg
      301 tcagttactt agctatttcc gcagtcttga ccgtaaactt gccggtgact ggtttatcta
      361 taacttcccg gccagaaccg gatgtgatgt ggatgctcac cttgtcagaa tgctggcgga
      421 aagctgcccg cggtttattg gcatcaaaga tactgtggac tgtgcgtctc acacccgggc
      481 catcgtcaac gcggtcacac cgctgagaaa agattttgcc gtattcgccg gttttgatga
      541 gtactttgta cccaatctga tgaacggagg cgccggagtt ctttccggac tgaataatgt
      601 ggtgccggag ctttttgccc aaattatgcg ggcctatcgg gccggcgacc tcaatgaagt
      661 cgccggatta cacaaagaaa ttgggcgact ttccgggata tatgccattg gtgatgattt
      721 tgtcagtacg atcaaaaccg ccatttccag aaagtatggc tacatgacgc cggtctcacg
      781 gaatcataac ggccagttaa cagccgacca ggcagactgc ctagacaaat tgttcggtct
      841 gtaaccgcaa aaggacagga ggcacatcat gaaaaaagac atcatttata ccaccggggc
      901 tcctgccccc ggtggggcat tatctcaggc ggtgaaagcc ggggaaacca tttatctcgc
      961 cggtcaggtc ggttttgacc cgcataccat gcaagtggtc tcaacagatt tcgatgaaca
     1021 ggcccgtcag gcgtttaaaa atttgctgtc ggtggcagag gccgcaggag ggagtgatag
     1081 ggatattgtg aagctgaatg cctatctgac cgacgtgaac atgttcccgc gatttaacgc
     1141 cattatgtcg gaatactttt cgccaccgta ccccgccagg gctacgttgg gtatcgccgc
     1201 cctgccgcag ggggctgtta ttgaaattga agccatcatg gtgctctgac tggccgtatc
     1261 tgacattaaa aagggacgat aatgaatatc aaaaaaacag ttgaaaaaat tccgggagga
     1321 atgatgctgg cccccctgtt tctgggggcg gtactgcata ccttctggcc aggtaccggc
     1381 aaatactttg gttcatttac taatggcatg atcaccggcg tggtccccat cctcgctgtc
     1441 tggctgttct gtatgggcgc ctccattaaa atcagtgcaa ccgggaccgt tctcaaaaag
     1501 tctggcacac tggtagccac aaaaatcgcc actgcctggg tctgtgcctt tgtttttgcc
     1561 cagctcctac cggaaggggg aatggtaaaa acaggtttct ttgccggttt atctgttctg
     1621 gcgattgttg cggcgatgga tatgaccaat gccgggcttt atgcttccct gatgcaggag
     1681 tacggcacaa aagaagaagc cggtgcttct gtacttatct cgcttgagtc cggccccctg
     1741 atgacgatga ttattctggg gtccgccggg caggcaacgt tcgaacctga acacctcgcc
     1801 ggcgtcctga tcccctttct ggtggggttt ttgctgggta atcttgatcc cgaacttcgg
     1861 gaattgtttt ccagggccac caaaagtctg atcccattct ttgcatttgc gttggggaat
     1921 accattaatc ttggcgtcat catcgacacc ggactgctgg gtattcttat ggctctggca
     1981 gtcattgtta tcacaggcgt accactgata atcatggata tcatgctggg taagggccgt
     2041 ggcacggctg gaattgccgc atcgagtact gctggcgctg ccgtggccac tccgttgctg
     2101 gtagccgaga tcgcgccgga cttcgctgag gccgcaccgg cagccaccac tctggtggca
     2161 tcctgtgtgg tgatcaccgc cattgtcgtg ccggtgatca ctgcgttgtg ggcaaaacac
     2221 ggagcctccc gcgtcagagc aacgtaaggc cgaacgccgc tcacgggtta tcatgacctg
     2281 tgagcggacc agtcatatac cgcataactt ttcagacatc atgccagcgg ctttcatcac
     2341 cgcgttcgca tactcaggta ttttttcctc aggcatctga aaacgaaccc cggaaatact
     2401 tattgcggca acaacggcct gatcactgtt aaataccggc gcggcaatac aggtgacatc
     2461 gtcgacatct tcctgattat caaacgccca tccctgcagg cggaccacct ccagctcagc
     2521 tttcaacgct ttacgtgttg taattgtccg ggcagtaaac gcaggaaggt gttctgtggg
     2581 taaaagagca tcaatgtggt cttccggaag ccaggccaac aacactttcc caagggagga
     2641 actgtgcagg gaaagtcgtt ttcccgtcca gctgcgaacg ataatcgcat tctggctttc
     2701 ttttttcgcc agatagatgc cggtggaacc atccagaacg cccagatggc aggcaagacg
     2761 ggtctggtca cggagaaaaa cgagtgactc ttcagccagt tcacgaaaat caaaatcctg
     2821 aatggcttta ttaccaagct cgtaaaagat tagccccaga taataccggc catttttttg
     2881 tctcagaaag gcatgcgtgg tcaggctggc aagcagggcc gaggtggtgc tttgaggcaa
     2941 tccgacattc tggtgaattt cactgtaggt ggcagagcct ttcccggcaa taaaatgaaa
     3001 tattcgggca gctttatcaa tggcaggcgt tttagttgcg atcatatcca ctgttcttcg
     3061 taagccccct ttttaatgaa ttgcaatgct gtaacaaacc atcatcctgc cacaggatac
     3121 gataatttac caaagtttca ctgacataac agcaagtccc ttctctttct caagtgatgg
     3181 tgtagtggcg actgacccct ggcagggcga tggaccacta cgtgaaccat caccccacac
     3241 acagggtgtt ttatgtgcag ttgtcaacca ctgaatcgtc accccaaagg ggcccccacg
     3301 attcagaagt tgacaattcg ggacctgaga ggaaataaaa gctagaagaa accactgtac
     3361 gtctctcatc cacgctcgta agcgtccctc acggcccgct aacgcggaga tacgccccga
     3421 ctgcgcacaa aggctctctc atagctgaaa gcgggtgtgg cttagcagga tggaaaaggg
     3481 taaggtgaaa tctatcaatc agtaccggct tacgccgggc ttcggcggtt ttacacctgt
     3541 gctacatgta acctccgtat gccgccttac atgcgctgac gcgcattatt tgccttgttc
     3601 cgtctgaaag taatcactat gattaaatat gattaacaac taatcggata tgcaaatgaa
     3661 aaacaatgcc gcacaagcaa caaaagtaat taccgcgcat gtgccattac ctatggctga
     3721 taaagtcgac cagatggccg ccagactgga acgttcccgg ggctgggtta tcaaacaggc
     3781 gctttctgca tggcttgccc aggaggagga gcgtaatcgc ctgacgctgg aagccctgga
     3841 cgatgtgaca tccggacagg ttatcgacca tcaggctgta caggcctggt cggacagcct
     3901 cagtactgac aatccgttac cggtgccacg ctgatggaac tgaagtggac cagtaaggcg
     3961 ctttctgatt tgtcgcggtt atttgatttt ctggtgctgg ccagtaaacc tgctgccgcc
     4021 agaacggtac agtccctgac acaggcaccg gtcattctgt taactcatcc acgtatggga
     4081 gaacagttgt ttcagtttga acccagggag gtcagacgga tttttgctgg cgagtacgaa
     4141 atccgttacg aaattaatgg ccagactatt tatgtattgc gtctgtggca cacacgagaa
     4201 aacaggtaga ttgtgtgtgg ggacaactta acatagcctg cagatattaa ttctggaaca
     4261 ttattatcag accagatatt ttgcattcca ttaaataatc ttgtag
//
LOCUS       DACAOP010000192         4304 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.193, whole genome shotgun sequence.
ACCESSION   DACAOP010000192 DACAOP010000000
VERSION     DACAOP010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4304
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.193"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..134)
                     /locus_tag="IT892_004436"
     CDS             complement(<1..134)
                     /locus_tag="IT892_004436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP3137552.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     R"
     gene            complement(249..324)
                     /locus_tag="IT892_004437"
     tRNA            complement(249..324)
                     /locus_tag="IT892_004437"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(289..291),aa:Thr,seq:ggt)
     gene            complement(331..405)
                     /locus_tag="IT892_004438"
     tRNA            complement(331..405)
                     /locus_tag="IT892_004438"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(370..372),aa:Gly,seq:tcc)
     gene            complement(522..606)
                     /locus_tag="IT892_004439"
     tRNA            complement(522..606)
                     /locus_tag="IT892_004439"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(570..572),aa:Tyr,seq:gta)
     gene            complement(615..690)
                     /locus_tag="IT892_004440"
     tRNA            complement(615..690)
                     /locus_tag="IT892_004440"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(655..657),aa:Thr,seq:tgt)
     gene            1052..2002
                     /gene="coaA"
                     /locus_tag="IT892_004441"
                     /gene_synonym="panK"
     CDS             1052..2002
                     /gene="coaA"
                     /locus_tag="IT892_004441"
                     /gene_synonym="panK"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAP3137553.1"
                     /translation="MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINE
                     DLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKS
                     TTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
                     SDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVF
                     VSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMT
                     LWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK"
     gene            complement(2031..2996)
                     /locus_tag="IT892_004442"
     CDS             complement(2031..2996)
                     /locus_tag="IT892_004442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HAP3137554.1"
                     /translation="MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLR
                     DWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELK
                     SGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEV
                     LRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESV
                     VNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPV
                     KLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK"
     gene            complement(2993..4021)
                     /gene="murB"
                     /locus_tag="IT892_004443"
     CDS             complement(2993..4021)
                     /gene="murB"
                     /locus_tag="IT892_004443"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAP3137555.1"
                     /translation="MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVL
                     ILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMP
                     GLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDSVELATGKQVRLTAKECRFGYRD
                     SIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKL
                     PDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKG
                     MQIGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGE
                     VSAVETIS"
BASE COUNT         1119 a         1079 c          956 g         1150 t
ORIGIN      
        1 cgagcagcac cgccgtaggt tttagccagt acggtagtga ttgcagcggt cagcgttgtt
       61 ttaccatggt caacgtggcc gatagtaccg acgttaacgt gcggttttgt acgttcaaac
      121 ttttctttag acatcgattg tccctctaag acacggataa atcggtgata tcaccacatc
      181 aaccaggcaa catgcccgac ttgttgaatg caataaacag aaggaaaaaa cagggaggag
      241 aaaagaagtg gtgctgatag gcagattcga actgccgacc tcacccttac caagggtgcg
      301 ctctaccaac tgagctatat cagcacatct tggagcgggc agcgggaatc gaacccgcat
      361 catcagcttg gaaggctgag gtaatagcca ttatacgatg cccgcatcct ggaactcggc
      421 tacctgattt tcattctgca ctgaatatcg agagaagctc tctttattcg agccggtaag
      481 cgaacttatc gtctcgggct acgccatcgc gtggccgaaa ttggtggtgg gggaaggatt
      541 cgaaccttcg aagtctgtga cggcagattt acagtctgct ccctttggcc gctcgggaac
      601 cccaccggac ttgatggtgc cgactaccgg aatcgaactg gtgacctact gattacaagt
      661 cagttgctct acctactgag ctaagtcggc atcaagtagc gcgcattcta tggagacatg
      721 cgagttcatg caactaaaaa attgcataat ttgttttatt ggtcacattt tatgcgacac
      781 gatgaaaaaa cagccgaacg gagggcagat tagcacactt tttcaacatc attgtgctca
      841 acaatgcgct cctgctaaac cataattctt tttatcagat ggaatatctg tcacattgct
      901 tttcaacgat agcttcctgg cagagatttt ttcttattat tcctccccat ctggtgttac
      961 cctcctgccc attaacccat tcaacagaac tgtgacgcgc catggcaaat atcgctttgc
     1021 cgatagagct atgaccgcca gaaacatgct tatgagtata aaagagcaaa cgttaatgac
     1081 gccttaccta cagtttgacc gcaaccagtg ggcagctctg cgtgattccg tacctatgac
     1141 gttatcggaa gatgagatcg cccgtctcaa aggtattaat gaagatctct cgttagaaga
     1201 agttgccgag atctatttac ctttgtcacg tttgctgaac ttctatataa gctcgaatct
     1261 gcgccgtcag gcagttctgg aacagtttct tggtaccaac gggcaacgca ttccttacat
     1321 tatcagtatt gctggcagtg tcgcggtggg gaaaagtaca accgcccgtg tattgcaggc
     1381 gctattaagc cgttggccgg aacatcgtcg tgttgaactg atcactacag atggcttcct
     1441 tcaccctaat caggttctga aagaacgtgg tctgatgaag aagaaaggct tcccggaatc
     1501 gtatgatatg catcgcctgg tgaagtttgt ttccgatctc aaatccggcg tgccaaacgt
     1561 tacagcacct gtttactcac atcttattta tgatgtgatc ccggatggag ataaaacggt
     1621 tgttcagcct gatattttaa ttcttgaagg gttaaatgtc ttacagagcg ggatggatta
     1681 tccacacgat ccacatcatg tatttgtttc tgattttgtc gatttttcga tatatgttga
     1741 tgcaccggaa gacttacttc agacatggta tatcaaccgt tttctgaaat tccgcgaagg
     1801 ggcttttacc gacccggatt cctattttca taactacgcg aaattaacta aagaagaagc
     1861 gattaagact gccatgacat tgtggaaaga gatcaactgg ctgaacttaa agcaaaatat
     1921 tctacctact cgtgagcgcg ccagtttaat cctgacgaaa agtgctaatc atgcggtaga
     1981 agaggtcaga ctacgcaaat aatttgcagg ggagcgaata ctcccctttc ttatttttct
     2041 gcactacgca gggatatttc accgcccatc cagggtttta ttattccatc ctgctcaagt
     2101 aataaagccc cctgtttgtc tattccgcgt gaaatgccaa atatttcttt atcaccaatg
     2161 ataagtttca ctgggcgatt aataaaatta tccagctttt cccagcgcga cagataaggt
     2221 gccaatcctt cttgttcgaa gagttccaac gcagcacgta attcacgtat tagcatggcc
     2281 gccaacgtat tacgatcgag attgatcccc gcttcctgca gcgtgatcca cccctgatta
     2341 acgacactct cttcaacacg gcgcattgcc atgttgatcc cggctccaat gactatttgc
     2401 gccgcatcgc cagttttgcc agtcagctcc acaagaatgc ctgccagctt gcgatcctgc
     2461 agatagaggt cattaggcca tttaacacga actttatctg cacccagctt gcgtaatact
     2521 tccgccatca cgataccgat aaccagactt aaaccaatcg ccgccgccgg gccttgttcc
     2581 agacgccaga acatcgacaa atataagttt gcgccaaaag gcgaaaacca tttccgaccc
     2641 cggcgaccac ggccagcctg ctggtattct gcaatgcaag catcgcccga tttaagctct
     2701 ccgatacgat caagaaggta ctgattcgtg gagtcaatca ctggcagcac ggctacacta
     2761 ccgccatcca gctgacccaa tatctgttta gcattaagta actggatagg ctcaggcagg
     2821 ctgtatcctt tacccggaac ggtaaagaca tcaacgcccc agtcacgcag tgtctgaatg
     2881 tgtttattaa tagccgcccg gctcattccc agcgtttcac ccaactgctc gccagagtga
     2941 aattcaccgt tcgctaacag ggcaatcaat ttcagtggca cggtgttatc cttcatgaaa
     3001 ttgtctccac tgcgctcact tcacctgatg caccaataaa gcggacttca ggctcaagcc
     3061 agacattaaa tttttcacca actttctgtc ttacatgatg cgccagctgt acaacatctt
     3121 cgctttttgc attgtcttca ttaatgagaa ctaacgcctg ttgacggtgc accgcagccc
     3181 cacctatttg catccctttt agctggcact gatcgataag ccaacctgct gccagtttta
     3241 ctgaaccatc cgcctggggg taatttggtg ctgttggaaa ttgtgacagt aatgctttag
     3301 ccgtttcggc agatacaaca gggtttttga agaaactacc ggcattgcca ttcacttttg
     3361 gatcagggag tttggtggtg cgcatatgac acaccgcatt aaatacttgc tgtggcgtta
     3421 ctgttgtagg atccagacga gttaagtcac catacgttag tacaggttgc cactcttttg
     3481 gcagacgcag acctacggct acaatagcga agcggtcctg gtattcatgt ttaaaaatac
     3541 tgtcgcgata gccaaaacgg cactctttgg cagttaagcg cacttgcttg cctgtcgcca
     3601 gttcaacaga atcaacataa gcgcaaactc gctgtaattc tacgccataa gcaccaatat
     3661 tctggatagg tgatgagccg acacaaccag gaattaatgc cagattttcc agaccaggca
     3721 taccttcctg caaagtgtat tttaccagac gatgccagtt ttctccggct cctacatgta
     3781 aataccacgc atcaggttca tcatgaattt cgataccttt gatccggttg atgatcaccg
     3841 tgccgcgata gtcctccaga aaaagtacat tacttccttc acccagaata agaacgggtt
     3901 gtccttctgc ggttgcatac tgccaggcat tgagtaattg ttgttcgtct tcggcacata
     3961 caatgtgctg agcattatga tcaatgccaa atgtgttcca gggttttaag gagtggttca
     4021 tagctgcttt cctgatgcaa aaacgaggct agtttaccgt atctgtgggg ggatggcttg
     4081 tagatatgac gacaggaaga gtttgtagaa acgcaaaaag gccatccgtc aggatggcct
     4141 tctgcttaat ttgatgcctg gcagtttatg gcggcgtcct gcccgccacc ctccgggccg
     4201 ttgcttcgca acgttcaaat ccgctcccgg cggatttgtc ctactcagga gagcgttcac
     4261 cgacaaacaa cagataaaac gaaaggccca gtctttcgac tgag
//
LOCUS       DACAOP010000193         4169 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.194, whole genome shotgun sequence.
ACCESSION   DACAOP010000193 DACAOP010000000
VERSION     DACAOP010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4169
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.194"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            245..853
                     /locus_tag="IT892_004444"
     CDS             245..853
                     /locus_tag="IT892_004444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HAP3137556.1"
                     /translation="MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFN
                     PLGKVPVLVTEEGECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMD
                     AGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIAC
                     AVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA"
     gene            951..2342
                     /gene="selA"
                     /locus_tag="IT892_004445"
     CDS             951..2342
                     /gene="selA"
                     /locus_tag="IT892_004445"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HAP3137557.1"
                     /translation="MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQML
                     DEAREVIRGSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAE
                     AAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLM
                     LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNEN
                     TALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEP
                     MPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAAL
                     EATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLS
                     QIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRC
                     LEDEQRFLEMLLK"
     gene            2339..>4169
                     /gene="selB"
                     /locus_tag="IT892_004446"
     CDS             2339..>4169
                     /gene="selB"
                     /locus_tag="IT892_004446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HAP3137558.1"
                     /translation="MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAY
                     WPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLT
                     GNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFITAATEGRGMDALREH
                     LLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRV
                     RALHAQNQPTETANAGQRIALNIAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHT
                     PLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDRLVLRDISARNTLAG
                     ARVVMLNPPRRGKRKPEYLQWLASLARAQSDADALSVHLERGAVNLADFAWARQLNGE
                     GMRELLQQPGYIQAGYSLLNAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMAL
                     PMEDEALVLLLIEKMRESGDIHSHHGWLHLPDHKAGFSEEQQAIWQKAEPLFGDEPWW
                     VRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRIVEFANMIRDLDQECGS
                     TCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRGNDHLLRDALL"
BASE COUNT          939 a         1062 c         1218 g          950 t
ORIGIN      
        1 gccggttttc cgctcatttc tcatccttgt tttatcgggt tatttgtctg ctgacaggcg
       61 aaaccctaca gatttataag aaagcctgaa gtgagatatc catcagagtg aaataattag
      121 gaaaatattt atatcaccat gataaatatg tgatttattt ggaagtaaca aaccatcaac
      181 attttctgcc ctttttccca tcaccaggcc atactgatat ttttcctcgc acaaaggact
      241 cggcatgaaa ctcgtcggta gctacaccag cccgtttgta cgcaaacttt ctattctgtt
      301 gttagaaaag ggcataactt tcgaatttat taatgaactg ccctataacg cggacaacgg
      361 cgtggcgcaa tttaacccgt taggaaaagt gccggtgctg gtgaccgaag agggcgaatg
      421 ctggtttgat tcgccgatca tcgctgaata tattgaatta atgaatgtcg ctccggcgat
      481 gttgccgcgc gatccgctgg agtcgttgcg ggtgcgcaaa attgaggcac tggcggatgg
      541 cattatggat gccgggctgg tatcggtgcg tgaacaggcg cgtccagcgg cgcagcagtc
      601 tgaagatgaa ttgttacgcc agcgggagaa aatcaaccgc agtctggatg tgctggaagg
      661 atatctggtc gatggcacac tcaaaaccga tacggtcaat ctggcgacta tcgccattgc
      721 ctgtgccgtc ggatatctca atttccgccg cgttgcgcca ggttggtgtg tcgaccgccc
      781 acacttagtc aaactggtcg aaaacctgtt tagccgcgaa agttttgctc gcaccgaacc
      841 gccaaaggct tgatgcgcga tatgtcctcc tgacccatct cacgttacaa tccgtggtta
      901 tgttaaacgc ccttctccgt gtgagagggc cttgatcagc caggtttcct atgacaaccg
      961 aaacgcgttc cctctatagt caacttccgg ctattgatcg cttattgcgc gatagctcct
     1021 tcctttcttt gcgtgatact tatggtcaca cccgcgtggt ggaattgttg cgtcagatgc
     1081 tcgacgaagc gcgagaagtg attcgtggca gccagacgct gcctgcgtgg tgtgaaaact
     1141 gggcgcaaga agtcgatgcc cggttgacga aagaagcgca gagcgcgctg cgtccggtga
     1201 tcaacctgac gggaaccgtg ctgcatacca accttgggcg agctttacag gcggaagccg
     1261 cggtggaagc cgttgcgcag gctatgcgtt cgccagtgac cctcgagtat gatctggacg
     1321 acgccggacg cggacatcgc gatcgggcgc tggcgcagct gctgtgccgt attacggggg
     1381 cggaagatgc ctgtatcgtc aataacaatg cggcggcggt gttattgatg ttggcggcca
     1441 ctgccagcgg aaaagaggtg gtggtatctc gcggcgaact ggtggagatt ggcggcgcgt
     1501 ttcgtattcc cgatgttatg cgtcaggcag gctgcaccct acacgaagta gggaccacca
     1561 accgcacgca cgcgaatgat tatcgtcagg cggtgaatga aaataccgca ctgttgatga
     1621 aagtacatac cagtaactac agcattcagg ggttcaccaa agcgatagat gaagcggaac
     1681 tggtggcgct cggcaaagag ctggatgttc ccgtagtgac tgatttaggc agtggctcgc
     1741 tggtcgatct tagccagtac ggtttgccga aagagccaat gccgcaggag ttgattgcgg
     1801 caggcgtcag tctggtgagt ttctccggcg acaagttgtt aggcgggccg caggcaggaa
     1861 ttattgttgg taaaaaagag atgatcgccc gcctgcaaag ccacccgctg aagcgtgcat
     1921 tacgcgcgga taaaatgacc ctcgcggcgc tggaagccac gttgcgtctt tatttacacc
     1981 ctgaagctct gagtgaaaaa ttaccgaccc tgcgcctgct tacccgcagc gcagaggtca
     2041 ttcaaatcca ggcacaacgt ttacaggccc cccttgccgc acattacggc gcggagtttg
     2101 cggtacaggt tatgccatgt ctttcgcaga ttggcagtgg ttcgctgccg gttgatcgcc
     2161 tgccgagcgc ggcattaacg tttacacccc atgatggacg cggtagccac cttgagtcat
     2221 tagccgcccg ctggcgtgaa ttgccagtgc cggtgattgg tcgtatttat gacggacgat
     2281 tgtggctgga tttacgctgc cttgaagatg agcaacggtt tttggagatg ttgttgaaat
     2341 gattattgcg actgccggac acgttgacca cggcaaaaca accttattgc aggcgattac
     2401 tggcgtaaat gctgaccgtc tgccggaaga aaaaaagcgc ggcatgacca tcgatctcgg
     2461 ctatgcctac tggccgcagc cggatggtcg cgtgcctggt tttatcgacg ttcccggtca
     2521 tgaaaagttt ctttccaaca tgctggcggg cgttggtggt atcgatcacg cgctgttggt
     2581 ggtggcgtgc gatgacggcg tgatggcaca gacccgtgag catctggcga ttttgcagct
     2641 gaccggtaac ccgatgctga cagtggcgct gaccaaagcc gatcgcgtgg acgaagcgcg
     2701 tgttgatgag gttgaacgcc aggtaaagga ggttctgcgg gaatacggtt ttgctgaggc
     2761 aaaactgttt atcaccgcag caaccgaagg tcggggaatg gatgccctgc gcgagcatct
     2821 gcttcagttg ccggaacgcg agcacgccag ccaacatagt ttccgcctcg cgattgaccg
     2881 cgcatttacc gtaaaaggtg ccgggctggt cgtcaccggt acggcgttaa gcggggaagt
     2941 gaaggtaggc gattcactct ggctgactgg tgtaaataaa ccgatgcgtg tacgtgcgct
     3001 gcatgcgcaa aaccagccaa cagaaaccgc caatgccggg cagcgtatcg cgcttaacat
     3061 cgcgggtgat gcggaaaaag agcagattaa ccgtggcgac tggctgcttg ccgatgtgcc
     3121 gccagagccg ttcacacggg tgattgtcga gcttcaaacc catacaccgc tgacccagtg
     3181 gcagccgctg catattcacc acgccgccag ccacgtcacg ggacgcgttt cactgctgga
     3241 agataacctt gctgaactgg tcttcgacac cccgttatgg ctggcagata acgaccgcct
     3301 ggtattgcgc gatatctctg cccgcaacac gctggccgga gcgcgcgtcg tgatgcttaa
     3361 cccgccgcgt cgcggtaaac gtaagccgga atatctgcaa tggctggcgt ctcttgcacg
     3421 ggcgcagagc gatgccgatg cgttatctgt tcatctggaa cgcggcgcgg ttaaccttgc
     3481 ggatttcgcc tgggcgcgcc agctcaacgg cgaagggatg cgcgaattgc tgcaacagcc
     3541 tggttatatt caggctggtt atagcttgtt gaatgcgccg gttgccgccc gctggcagcg
     3601 gaaaattctc gacacattag cgacttatca tgagcaacat cgcgatgaac ctggccctgg
     3661 gcgcgaacgt ctgcgacgta tggcgttgcc aatggaagat gaagcgctgg tactgttgct
     3721 gattgaaaag atgcgcgaaa gcggcgacat ccacagccat cacggctggc tgcatctgcc
     3781 agatcacaaa gcgggcttca gcgaagagca gcaggccatc tggcaaaaag cagagccact
     3841 gtttggtgac gaaccgtggt gggtgcgtga cctggcaaaa gagacgggaa ccgacgagca
     3901 ggcaatgcgc ctgactctac gccaggcggc gcagcaagga ataattaccg cgatcgttaa
     3961 agatcgttat taccgtaacg atcggattgt cgagtttgcc aatatgatcc gcgatctcga
     4021 tcaggagtgt ggttcaacct gcgcggcgga tttccgcgat cgcttaggcg taggccgaaa
     4081 gctggcaatt cagattctgg aatattttga ccgcattggc tttacgcgtc gtcgtggaaa
     4141 tgatcattta ttgcgcgacg cattattat
//
LOCUS       DACAOP010000194         4143 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.195, whole genome shotgun sequence.
ACCESSION   DACAOP010000194 DACAOP010000000
VERSION     DACAOP010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4143
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.195"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            97..861
                     /locus_tag="IT892_004447"
     CDS             97..861
                     /locus_tag="IT892_004447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002008502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS6100 family transposase"
                     /protein_id="HAP3137559.1"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDH
                     TTIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTID
                     FYLSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETA
                     HRQVKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQ
                     PGIRGEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
     gene            complement(1354..1938)
                     /locus_tag="IT892_004448"
     CDS             complement(1354..1938)
                     /locus_tag="IT892_004448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP3137560.1"
                     /translation="MPRPKLKSDDEVLEAATVVLKRCGPIEFTLSGVAKEVGLSRAAL
                     IQRFTNRDTLLVRMMERGVEQVRHYLNAIPIGAGPQGLWEFLQVLVRSMNTRNDFSVN
                     YLISWYELQVPELRTLAIQRNRAVVEGIRKRLPPGAPAAAELLLHSVIAGATMQWAVD
                     PDGELADHVLAQIAAILCLMFPEHDDFQLLQAHA"
     gene            complement(1938..3176)
                     /locus_tag="IT892_004449"
     CDS             complement(1938..3176)
                     /locus_tag="IT892_004449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP3137561.1"
                     /translation="MSERRYSPLATLFAATFLFRIGNAVAALALPWFVLSHTKSAAWA
                     GATAASSVIATIIGAWVGGGLVDRFGRAPVALISGVVGGVAMASIPLLDAVGALSNTG
                     LIACVVLGAAFDAPGMAAQDSELPKLGHVAGLSVERVSSLKAVIGNVAILGGPALGGA
                     AIGLLGAAPTLGLTAFCSVLAGLLGAWVLPARAARTMTTTATLSMRAGVAFLWSEPLL
                     RPLFGIVMIFVGIVGANGSVIMPALFVDAGRQVAELGLFSSMMGAGGLLGIAIHASVG
                     ARISAQNWLAVAFCGSAVGSLLLSQLPGVPVLMLLGALVGLLTGSVSPILNAAIYNRT
                     PPELLGRVLGTVSAVMLSASPMVMLAAGAFVDLAGPLPGLVVSAVFAGLVALLSLRLQ
                     FATMAAAATASAPTHTEGEH"
     gene            complement(3173..4078)
                     /gene="mph(A)"
                     /locus_tag="IT892_004450"
     CDS             complement(3173..4078)
                     /gene="mph(A)"
                     /locus_tag="IT892_004450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HAP3137562.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAQLAAAE"
BASE COUNT          857 a         1296 c         1292 g          698 t
ORIGIN      
        1 ctgcaccaat ctcgactatg ctcaatactc gtgtgggctc tgttgcaaaa atcgtgaagc
       61 ttgagcatgc ttggcggaga ttggacggac ggaacgatga cggatttcaa gtggcgccat
      121 ttccagggtg atgtgatcct gtgggcggtg cgctggtatt gtcgctatcc gatcagctat
      181 cgcgaccttg aggaaatgct ggcggaacgc ggcatttcgg tcgaccatac gacgatctat
      241 cgctgggtcc agtgctacgc cccggagatg gagaagcggc tgcgctggtt ctggcggcgt
      301 ggctttgatc cgagctggcg cctggatgaa acctacgtca aggtgcgggg caagtggacc
      361 tacctgtacc gggcagtcga caagcggggc gacacgatcg atttctacct gtcgccgacc
      421 cgcagcgcca aggcagcgaa gcggttcctg ggcaaggccc tgcgaggcct gaagcactgg
      481 gaaaagcctg ccacgctcaa taccgacaaa gcgccgagct atggtgcagc gatcaccgaa
      541 ttgaagcgcg aaggaaagct ggaccgggag acggcccacc ggcaggtgaa gtatctcaat
      601 aacgtgatcg aggccgatca cggaaagctc aagatactga tcaagccggt gcgcggtttc
      661 aaatcgatcc ccacggccta tgccacgatc aagggattcg aagtcatgcg agccctgcgc
      721 aaaggacagg ctcgcccctg gtgcctgcag cccggcatca ggggcgaggt gcgccttgtg
      781 gagagagctt ttggcattgg gccctcggcg ctgacggagg ccatgggcat gctcaaccac
      841 catttcgcag cagccgcctg atcggcgcag agcgacagcc tacctctgac tgccgccaat
      901 ctttgcaaca gagcccgccg tgctagtctg ctcggtgatg gtggagtgaa gccaacccgc
      961 aatcgggtta tgaatctgca tcgcgattcg caatcagctg tctcttgagc atgtcgaact
     1021 cctgcgatgt tatctcgccg tgctcgtgct gctacaccaa cttgtccaac tcatccgcca
     1081 caccgctccc caccacctgc gatggccagg ttgtttgctg ggcgcattgg cggagtatcg
     1141 tctcgacccg ggacacccac accggcacaa ccttacggga gtgattcact gtcaaagaat
     1201 cggcccggtg ctctgacgca agtatcggga tggtcaccat ttgtaagccg tagacctgag
     1261 tggtgatcaa gacttcgata ccaccgaccg taccggtact aatcgacgac ggtcgtgttc
     1321 gtcgcctgcc gcagggactc tgcacacctc cgtttacgca tgtgcctgga ggagttggaa
     1381 atcgtcgtgt tcgggaaaca ttaaacacag gatggcagcg atctgagcca gcacatgatc
     1441 agctagctca ccatccggat cgacggccca ctgcatcgtc gcgccagcga tgaccgagtg
     1501 caggagcaac tcagctgccg caggagcacc tgggggcagt cgcttgcgga tcccctccac
     1561 caccgcgcgg ttccgctgga tcgcaagcgt gcgtagctcc ggcacctgga gctcgtacca
     1621 ggagatgaga tagttcaccg agaagtcgtt gcgagtgttc atgctccgaa cgagcacctg
     1681 caaaaattcc cagagccctt gcggccctgc gcctatcggt atcgcattca ggtaatgccg
     1741 cacctgctcg acgccgcgct ccatcatcct caccagcagc gtatcgcggt tggtgaagcg
     1801 ctggattaac gctgcgcggg agagccccac ctcctttgct actccgctga gcgtgaactc
     1861 tatgggaccg caacgcttca gcactacggt ggcggcctcg agtacctcgt catcggactt
     1921 gagcttgggg cggggcatca gtgttcacct tctgtatggg ttggggcgga ggctgtggct
     1981 gccgccgcca ttgtagcaaa ttgaagacgg agcgagagta gagccacgag ccccgcaaac
     2041 acggccgata caacgaggcc agggagcgga ccagcaaggt cgacaaacgc gccggccgca
     2101 agcataacca tgggcgaggc tgacagcatc accgccgaga ccgtgccgag tacccggccg
     2161 agaagttctg gcggcgtgcg gttgtagatg gcagcgttga gaatgggaga gactgagccg
     2221 gtcagcagtc ccacgagcgc gcccaacaac atcagcaccg gcacgcctgg caactgtgaa
     2281 agcagaagcg agcccaccgc agagccacaa aatgccaccg ccagccagtt ctgcgctgat
     2341 atccgggcgc cgaccgacgc atgaatggca atgccaagga gaccaccagc ccccatcatt
     2401 gaggagaaca gcccgagctc tgctacttgg cgtcctgcat ctacaaacag cgcaggcatg
     2461 atgacgctgc cgttggcgcc aacgatgccc acgaagatca tcactatacc aaagagaggg
     2521 cgcagcaggg gttcgctcca gagaaaagcg acgccggcgc gcatggagag agtcgccgtc
     2581 gtggtcatcg tccgagcggc acgcgcggga agcacccacg cgccgagcag acctgcaagg
     2641 acggagcaga acgccgtcag cccgagcgtt ggcgcagcgc caagcaggcc gattgcggcc
     2701 cccccaaggg ccgggccacc tagaatcgcg acgttcccga tcaccgcttt cagtgacgag
     2761 acgcgctcaa cggagagccc ggcgacgtgg ccgagtttgg gcagctcact gtcctgcgcg
     2821 gccataccgg gtgcgtcgaa cgcggcaccg agcaccacgc aagcgatcag cccagtgttc
     2881 gagagggcgc caacggcatc gagcagtggg atgctcgcca tggccacgcc gcccaccaca
     2941 cccgagatca atgcgacggg cgcgcgcccg aaccgatcga cgaggccacc accaacccac
     3001 gcgccgatga tggtcgcgat gacgctgcta gcggccgtgg cgcccgccca ggccgcgctc
     3061 tttgtatgag acaggacgaa ccatggaagc gcgagggccg ccaccgcgtt gccgatccgg
     3121 aagagaaagg tcgccgcgaa cagcgtcgcg agcgggctat atcgacgttc gctcattccg
     3181 ctgcggcgag ctgcgccttc gccgcagcga ggtactcttc gttacccgag tcgagggcga
     3241 agagtgcgta ggtgaccgcc ccgaacgcaa ggcgctccgc gatgtggtgg gcgagccgcg
     3301 gccacacccg gccaccggcc gcttcatacg tgaggaggag cttcgcgagc ccctcttcac
     3361 caaagaccat aaggtgcgcg gccatgtcga tggcagggtc atcaacgcgg gcctcgctcc
     3421 agtcgatcat cccgctgacg cgctccgtgt tgtcgatgag cacatggccc acgtagagat
     3481 cgccatgcac caccacggag aaatctggcc acgacgaatc gtcgtcgagc cagcgctgcc
     3541 accggtggag gcgcttgtcg ttcaccacga actcgcgtcg gacgcggtca acgtcgtcgg
     3601 ccaccttctg acgggcctgc gtcggtgtac ggatgagcat ccccgcatcc acggcggcgg
     3661 aaatggggac ggcatgcagg gcggcgagcg cggtcgcgaa gctctccgcg aagacctccg
     3721 agtcctgcgg cacgacccag tcgggcgtgg acgaaccagg ctggatgacc atcgcagtcg
     3781 agtcttcgag catgggatag gcaacgagct cggcgttggc cacgcgccag tccggcaccg
     3841 cgaacggcag gcgattcttg agcattgcca gcacccgcgc ctctggttcg accttcgcgc
     3901 ttacctcggc tcggcgcggg atgcgcagca cccaccgacg tccatcgtcg acggtggcga
     3961 tcacgatcct atagtcgagc ccaagctcat tgacagtcag cgggccatgg agcttgagcc
     4021 catgtcgggc tgcaagtgcg tacagttggg aggtatcggc ggtcgtgact acggtcatga
     4081 ttcactcctg agggcttgac gggtttagcc acctaaatgt aacagtcacg tcggttatat
     4141 tca
//
LOCUS       DACAOP010000195         4139 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.196, whole genome shotgun sequence.
ACCESSION   DACAOP010000195 DACAOP010000000
VERSION     DACAOP010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4139
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.196"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            160..588
                     /gene="uspC"
                     /locus_tag="IT892_004451"
     CDS             160..588
                     /gene="uspC"
                     /locus_tag="IT892_004451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspC"
                     /protein_id="HAP3137563.1"
                     /translation="MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPE
                     MYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCHKHH
                     FDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLMGD"
     gene            complement(595..2019)
                     /gene="otsA"
                     /locus_tag="IT892_004452"
     CDS             complement(595..2019)
                     /gene="otsA"
                     /locus_tag="IT892_004452"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalose-phosphate synthase"
                     /protein_id="HAP3137564.1"
                     /translation="MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSG
                     ETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQFSNAVLWPAFHYRLDLVQFQRPA
                     WDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPT
                     PEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKA
                     FRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLA
                     YEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLY
                     YLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAA
                     NELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISD
                     LKQIVPRSAESQQRDKVATFPKLA"
     gene            complement(1994..2794)
                     /gene="otsB"
                     /locus_tag="IT892_004453"
     CDS             complement(1994..2794)
                     /gene="otsB"
                     /locus_tag="IT892_004453"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HAP3137565.1"
                     /translation="MTEPLTETPELSAKYAWFFDLDGTLAEIKPHPDQVVVPDNILQG
                     LQLLATASDGALALISGRSMVELDALAKPYRFPLAGVHGAERRDINGKTHIVHLPDAI
                     ARDISVQLHTVIAQYPGAELEAKGMAFALHYRQAPQHEDALMTLAQRITQIWPQMALQ
                     QGKCVVEIKPRGTSKGEAIAAFMQEAPFIGRTPVFLGDDLTDESGFAVVNRLGGMSVK
                     IGTGATQASWRLAGVPDVWSWLEMITTALQQKRENNRSDDYESFSRSI"
     gene            complement(2961..3950)
                     /locus_tag="IT892_004454"
     CDS             complement(2961..3950)
                     /locus_tag="IT892_004454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose ABC transporter permease AraH"
                     /protein_id="HAP3137566.1"
                     /translation="MMSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVP
                     NFATFINMKGLGLAISMSGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTES
                     LWIGVAAGLLLGVLCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIED
                     ESFFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPV
                     VRTKIIIFVLSGLVSAIAGIILASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGK
                     ISYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRYKQKAKRTV"
     gene            complement(3962..>4139)
                     /gene="araG"
                     /locus_tag="IT892_004455"
     CDS             complement(3962..>4139)
                     /gene="araG"
                     /locus_tag="IT892_004455"
                     /EC_number="7.5.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127704.1"
                     /note="Part of the ABC transporter complex AraFGH involved
                     in the high affinity transport of arabinose; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="L-arabinose ABC transporter ATP-binding protein
                     AraG"
                     /protein_id="HAP3137567.1"
                     /translation="AQGVAVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQ
                     ALSLAMPKVSQAVA"
BASE COUNT         1076 a         1072 c          975 g         1016 t
ORIGIN      
        1 tacatttgaa attatatgat caccgggagt gattgattaa ttgtctttac taataatcag
       61 actaatattt acctgtttga ccgagttggg attgcgtcgt ttctccatta ggagtaaagc
      121 tttaatgtca cctgaagttc acagaataag gaacaggtta tgagctatag caatattctt
      181 gtcgctgttg cggttacacc ggaaagtcag caactgctgg caaaagcggt atctatcgcc
      241 aggccagtaa agggacacat cagtttaatt actctcgctt ccgacccgga aatgtacaat
      301 caattagccg cgccgatgct tgaagattta cgcagcgtga tgcaagaaga aacgcaaagc
      361 tttcttgata agttaattca ggatgcgggg tatcccgttg acaagacgtt tattgcctac
      421 ggtgagttaa gcgaacatat tctggaagta tgtcacaaac atcatttcga tttggtgatt
      481 tgcggtaatc acaatcacag tttcttttcg cgagcatcct gctcggcgaa aagagtgatt
      541 gcctcaagtg aggtcgatgt gctgttagtt ccacttatgg gtgattaacc gctcctacgc
      601 aagctttgga aaggtagcaa ctttatcgcg ctgctggctt tccgcgcttc gcggaactat
      661 ctgctttagg tcgctaatga agcactcctg ccagtggtta atatcgtttt tcacgataac
      721 gtccagcatt tctgcatgac gggaaatacg ttccgccagc gacatagtca atgcacgatc
      781 cagcgcagct gcaacttcgt cacgatcgta ggggttaaca attaacgccg acgttaactc
      841 gtttgccgct cccgcaaatt gcgaaagaac aagaacgccc ggattggctg ggtcctgagc
      901 agcaacatac tcttttgcta ccaggttcat cccgtcacgc agtggcgtca ctaagcccac
      961 gtcagagtag cggaatattt tcatcagtaa tttacggtca aaatgctgat tcaaataata
     1021 aagcggcgtc cagcctaatt gcccgtattt accattaatt cgtccagctt cattttcgag
     1081 ctgatgacga atatcctgat aggcttgcac atcaccacgc gacgttggtg caatctgggt
     1141 ataacgaatt ttaccatgat gctgcggata tttttccagc aacgcttcat aggcgagaaa
     1201 acgctctggc aaacctttgg aataatccag ccgttcgaca gaaaagatat tttgtacgtt
     1261 tttcagttcc gctttaagtt gcgccagttt tggcggcagt ggcccggcag cctgtttggc
     1321 tatttctttc ggttcaatgc cgatcgggta gacttctgtt cgaaatgctt tgccccaggc
     1381 tgtatggctt tttgcgctac gtgtcgtgac gcgggtcagg ttagaaagac aatccaggaa
     1441 cgccagacga tcgttttctg tctggaaacc cagcaaatca taatcacaaa gctgttcaag
     1501 caaggtgtca tatgtcggca gcgcgttgaa gatttccggt gtcgggaaag gaatatgcag
     1561 aaagaaacca atgcgattat tcactccccg tttgcgtaat tcatgcgcaa atggcaacag
     1621 gtgataatcg tggatccaga taatgtcatc gtcttgcaac agcggcagta atttatctgc
     1681 cagcaacgca tttacgcgta gatagccgtc ccaggcagga cgctgaaatt gcaccagatc
     1741 gagccgataa tgaaaagcgg gccagagaac ggcattggag aattggttgt agtattcgtc
     1801 aaggtcctgt tcgctgaggt taaaagaggc ccacgtaatg ttaccttttt tcaccttttt
     1861 tagcggctga tcctcattcc ctgtttcacc actccagcca aaccacagtc cgcctgcggc
     1921 tttcagtgcc cccagtatgc caacggcaag gccaccggca ctggcggcgt gctcgtctgg
     1981 tggtgcaatc cggttagata ctacgactaa acgactcata gtcatcactc ctgttatttt
     2041 ctcttttttg ttgtaatgcg gtggttatca tttcaagcca gctccagaca tccggcacac
     2101 ccgccagtcg ccatgatgcc tgagttgcac ctgtgccaat ttttactgac attccgccca
     2161 gtcggttaac gactgcgaag ccagattcat cggttaaatc atcgcccaga aatacgggcg
     2221 ttcgcccgat aaagggagct tcctgcataa aagctgcaat tgcctcacct ttactggtac
     2281 ctctcggttt gatctcgaca acacactttc cctgctgtaa cgccatttgt ggccagatct
     2341 gagtaatacg ttgcgctaat gtcattaatg cgtcttcatg ctgcggagcc tgacgataat
     2401 gcagcgcaaa agccatccct ttcgcctcca gctccgcgcc gggatactga gcgatgactg
     2461 tatgcagttg cacgctaata tcacgcgcaa tcgcatccgg cagatgaacg atatgtgttt
     2521 taccattgat gtcacggcgc tccgccccat gcacgcccgc taacgggaag cgataaggtt
     2581 ttgccagtgc gtcaagctcc accattgagc gccctgatat caatgccaat gcaccatcac
     2641 ttgcggttgc cagtagctgt agtccttgca gaatattgtc aggcacgacg acctgatcgg
     2701 gatgcggttt gatttccgcc agcgttccat caagatcaaa aaaccaggca tatttcgcgg
     2761 atagttcagg ggtttcggtt aacggttctg tcacccggtt ctcctccttc tcttttctta
     2821 ttgtgttgcg cagaacgcgc tttacagaca tgtaagtata gacagtgtga cgggggtcgc
     2881 catttgcaac gaagaacagc caaccgttat ggcggttggc tatggtggga aaaaacgcta
     2941 aattgttgca gaaaaaagca tcagacagtg cgtttcgctt tttgcttgta acggtcgaag
     3001 atcaccgctg ccagcaggat taagccgcga accacgtact gcgcgaaagg agaaatatta
     3061 agcaggttca tggcgttttc cacggtgcct aaaattaaga tacccgccac cacatatgag
     3121 atttttccga tgccaccttt cagagaaacg ccacctaaaa cgcaggcgga gataacaatc
     3181 agctcataac caatcgacgt cattggctgc ccactggtca tacgtgaagc cagaataatt
     3241 ccggctatcg ctgataccag gcctgagaga acaaagataa taattttggt gcgaacaacc
     3301 ggtacacccg ccagacgcgc ggcctcttcg ttcccgccaa tcgccagggt gttacgacca
     3361 aaggtggttt tattcagcag caaaccaaag ataatcagac acgcgacggt gagccagatt
     3421 ggcgcaggca gaccgaacca gttggcgtaa ccaagggcaa agaagctttc atcttcgata
     3481 ccgaccgctt taccgtctga aatgatgtac gccagacctc gaacaatctg catcgttgcc
     3541 aatgtcgtga tcagagcatt tattttcagt ttggcgataa caaagccatt gaccaggcca
     3601 cagagaacgc ccagcaacaa ccccgctgcc acgccaatcc acaggctttc agtcaggtta
     3661 ataaccaccg ccgtggtgac acccgcacag gcaattacgg aggcgacaga aaggtcaaag
     3721 tcaccggaag cgaggcagaa caacatgcca caagccacca tccccgacat ggaaattgcc
     3781 aggcccaacc ctttcatatt aatgaaggtg gcaaaatttg ggacaaaaat ggcacaggcg
     3841 ataaagagca ccgcaaacac caccagcatg ccgtactgat cccagatacg cccgaagctg
     3901 aatgacgact taggtgcgcc agaccccgat gtagaaacag aagacatcat actctcctta
     3961 ctcaggcaac agcctggctg actttaggca tcgcaaggct cagtgcctga cgctcatctg
     4021 cctgctcgtg taacaattca ccggcgattt caccttcccg catcaccaca atccggtcgg
     4081 caacgccgag gacttcaggt aagtcgctgg aggcaaacag caccgccacg ccctgcgcc
//
LOCUS       DACAOP010000196         3961 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.197, whole genome shotgun sequence.
ACCESSION   DACAOP010000196 DACAOP010000000
VERSION     DACAOP010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3961
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.197"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            475..1914
                     /locus_tag="IT892_004456"
     CDS             475..1914
                     /locus_tag="IT892_004456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule assembly Wzi family protein"
                     /protein_id="HAP3137568.1"
                     /translation="MIKIARIAVTLGLLSSLGAQAYAAGLVVNDNDLRNDLAWLSDRG
                     VIHLSLSTWPLSQEEIARALKKAKPSYSSEQVVLARINQRLSALKADFRVTGYTSTDQ
                     PGTPQGFGQTQPADNSLGLAFNNSGEWWDVHLQGNVEGGERISNGSRFNANGAYGAVK
                     FWNQWLSFGQVPQWWGPGYEGSLIRGDAMRPMTGFLMQRAEQAAPETWWLRWVGPWQY
                     QISASQMNQYAVIPHTKIIGGRFTFSPFQSLELGASRIMQWGGEGRPESFSSFWNGLT
                     GKDNTSANDPNEPGNQLAGFDFKYKLEPTLGWPISFYGQLIGEDEAGFLPSANMYLGG
                     IEGHHGWGKDALNWYLEAHDTRTNMSRTGYSYWHHLYTDGYYQQGYSLGDAMGGDGQL
                     LAGKVELITEDNQRWSSRLVYAKVNPESQSINKAFPHADTLKGIQLGWSGDVYRSVRI
                     NTSLWYTNANNSDSDDVGASAGIEIPFSL"
     gene            2060..3193
                     /locus_tag="IT892_004457"
     CDS             2060..3193
                     /locus_tag="IT892_004457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HAP3137569.1"
                     /translation="MKKKIVRFSALALAIGFLTGCTIVPGQGLNSLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLIDQLRPATVLARPNPQLDNLLRSYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKILVAGKTLSQVRQDIANRLTTYIESPQ
                     VDVSIAAFRSQKTYVTGEVIKSGQQPITNIPLTVMDAINAAGGLAPDADWRNVVLTHN
                     GKDTKISLYALMQKGDLSQNHLLYPGDILFVPRNDDLKVFVMGEVGKQSTLKMDRSGM
                     TLAEAIGNAEGISQEFSDATGIFVVRQLKEDKQGKIANVYQLNAQDASAMVLSTEFQL
                     QPYDIVYVTTAPLVRWNRVISQLVPTIAGVHDMTETGKYIRTW"
     gene            3187..3633
                     /locus_tag="IT892_004458"
     CDS             3187..3633
                     /locus_tag="IT892_004458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004144167.1"
                     /note="Wzb shows phosphatase activity towards the
                     autophosphorylated Wzc protein, which induces colanic acid
                     biosynthesis; catalyzes the phosphorylation of UDP-glucose
                     dehydrogenase, an enzyme involved in colanic acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="HAP3137570.1"
                     /translation="MVKIMFNSILVICTGNICRSPFAERILRNKLPNMRVDSAGTGAL
                     VDSAADSTAMRIAKSFDVSLDGHKGKQFSAKLGREYDLILVMERAHITQISSIAPEVR
                     GKTMLLNHWVNQKDIPDPYRKSDEAFESVFNLIEKACFKWVEKLNG"
     gene            3652..>3961
                     /locus_tag="IT892_004459"
     CDS             3652..>3961
                     /locus_tag="IT892_004459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HAP3137571.1"
                     /translation="MSSTKSNKRLSADEIDIGRLYGELIDHRKLILSITAISVFISIL
                     YCLFATPIYQADALIQVEQKQGNTILESLSQVLPDAQPQSAPEISLLQSRMVLGKTVD
                     D"
BASE COUNT         1111 a          783 c          985 g         1082 t
ORIGIN      
        1 acgccgctaa aaataaaggc ctgaccaatt tatcacctac aggccgatta aatacgccgt
       61 tcaggtagtc agtgcgctgg tagctgttaa gccaggggcg gtagcgtcgc tgaaatcgcc
      121 tgctgcaaca caaaacacct tctttgaatg gctataaaaa tcgacacgct ctgggtgatt
      181 aacgctatga gatatctatc atgctcatca gatatcctca taaaggggtc aggcgcggct
      241 gctgatatcc cctgtacact aactttcctg tctcattgat agcctgtacg gtaaaattcg
      301 cctacattgt gagctgggtg gaagtgataa tggtgacaag cagcttaggg taactgtact
      361 tgcctcgccg gtgttgcaca gtgaagtcag ctggtgccgc gagcgctttc tatcttggta
      421 ttcccctcat tctcattgag atacgacagc ggggttgaaa atggatcttg tacaatgata
      481 aaaattgcgc gaattgccgt gacattgggc ttgctttcct cattgggagc ccaggcttac
      541 gcggccgggt tagtagtaaa tgataacgat ctgcgaaacg accttgcctg gctttccgat
      601 cgcggggtca tccatctgag cctgtcgacc tggccgctga gccaggaaga gatcgcccga
      661 gcactaaaaa aggccaaacc atcctattct tctgagcagg tagttctggc ccgtatcaac
      721 cagcgactgt ctgctttaaa agccgatttc cgggtcaccg gctatacctc gaccgaccag
      781 ccgggcaccc cgcaggggtt cggtcagacg cagccggcag ataactcctt aggcctggcg
      841 tttaataaca gcggcgagtg gtgggatgtc cacctccagg gcaacgtcga agggggagag
      901 cggatcagca acggctcgcg cttcaacgcc aacggcgcct atggcgcggt gaagttctgg
      961 aatcagtggc tctcctttgg ccaggtaccg cagtggtggg gacctgggta tgaaggtagc
     1021 ttgatccgcg gggatgcgat gcggccgatg accggctttc tgatgcagcg ggcagagcag
     1081 gcggcaccgg aaacttggtg gctgcgctgg gtgggcccat ggcagtatca gatttctgcc
     1141 agtcagatga atcagtacgc agtaatccct catactaaaa ttattggtgg tcgatttaca
     1201 ttctcgcctt ttcagtcttt agaattaggc gcatcgcgca ttatgcagtg gggcggagaa
     1261 ggtcggccag agtcatttag tagtttttgg aatggtttga caggaaaaga taacacttct
     1321 gctaacgacc caaatgaacc tggcaaccaa ttggctggat tcgactttaa gtataagctt
     1381 gaacctactc tcggttggcc aattagtttt tacggtcaat tgattggtga ggatgaggct
     1441 ggatttttac cctccgctaa tatgtacctc ggtggtatag aagggcatca tggatgggga
     1501 aaagatgcgc taaattggta tttagaagcc catgatacga gaacaaacat gagtagaacc
     1561 ggatatagct attggcatca tctttataca gatggctatt atcaacaagg ctactctctt
     1621 ggtgatgcga tgggaggaga tgggcagtta ttagctggca aggtcgagct tataacagag
     1681 gataatcaac gctggagttc acgtctggtt tacgccaaag taaatcctga gagtcagtcg
     1741 ataaacaagg cattccctca tgctgataca ttaaaaggaa ttcaactggg gtggagtgga
     1801 gatgtttacc ggtctgttcg tataaatact tcactttggt ataccaacgc taacaacagc
     1861 gatagtgatg acgttggagc cagcgcaggg atagagatac cgtttagttt ataaggctga
     1921 atgctgaaaa taggggagag aaagtggtag cgctgcagga cgcagtcagc ttttgtctct
     1981 ctattagccg gcaaggatgc aacggttatg acagctgctc aggaattggc aaattttgat
     2041 ttactgatga tgtgacatta tgaagaaaaa aattgttaga ttttcggcat tagcattggc
     2101 aatcgggttt ctaacaggtt gtactattgt tccaggccaa gggttaaata gtctacgtaa
     2161 gaatgttgtt gaactccccg acagcgacta cgatctcgat aagttggtaa atgtttatcc
     2221 catgacgcca ggcctaatag accagcttcg tccggcaacc gttcttgctc gcccaaatcc
     2281 gcagttggat aatttactac gtagttacga atatcgtatt ggtgtaggtg atgtactgat
     2341 ggttactgta tgggaccatc cggaattaac tactcctgct ggccagtata ggagtgcaag
     2401 tgataccggg aattgggtaa attcagatgg cacaatattt tatccctaca tcggaaagat
     2461 acttgtagcc gggaaaacac ttagtcaagt acgccaggat atagcaaatc gtcttacaac
     2521 ttatattgag agcccgcagg tcgatgttag catagctgct tttagatcac aaaagaccta
     2581 tgttacaggt gaagtaatta aatcaggaca gcagccaatt acaaatattc cgcttacggt
     2641 tatggatgca ataaacgctg caggtggact tgcacctgat gcagactggc gtaacgttgt
     2701 tttaacccat aatgggaagg atacaaaaat ctcattatat gcattaatgc aaaagggtga
     2761 tttgtcacag aatcatctcc tttatcctgg tgatattctt tttgttcccc gtaatgatga
     2821 cctgaaagtg tttgtcatgg gcgaagttgg taagcaaagc actcttaaga tggatcgaag
     2881 tggtatgact ttagctgagg ccattgggaa tgcggaaggt atttctcagg aatttagtga
     2941 tgcaacgggt atctttgtcg ttcggcaact gaaagaggat aaacaaggca agatagcaaa
     3001 tgtttaccaa ctaaatgctc aagatgcttc agcgatggta ctgagcactg aatttcagtt
     3061 acaaccttat gatatcgttt atgtaactac tgccccattg gttcgatgga atcgggttat
     3121 atcacagttg gtgcctacaa ttgctggtgt acatgatatg actgagacgg gtaaatatat
     3181 tcgaacttgg tgaaaataat gtttaattct attttagtta tatgcacagg aaacatctgc
     3241 cgttcacctt ttgcagaaag aatattaagg aacaaactgc cgaatatgag ggtcgactcg
     3301 gcaggaactg gagcgttagt tgatagcgct gctgattcta cagcaatgag aattgccaaa
     3361 tcttttgatg tttctttgga tggacataaa ggtaaacaat ttagcgcaaa gttaggaagg
     3421 gagtatgatc ttatcttggt gatggaaaga gcccatatta cacaaattag tagtattgca
     3481 cctgaagtta gaggtaaaac tatgttgttg aatcattggg taaatcaaaa agatattcct
     3541 gatccttacc gaaaaagtga tgaagctttc gaatcagttt ttaatttgat cgaaaaagca
     3601 tgctttaaat gggttgaaaa attaaatgga tgaaatttgg gaacataact aatgtcttct
     3661 acgaaatcta ataaacgact cagcgcagat gaaattgaca ttggtcgtct gtatggtgaa
     3721 ttaattgacc atcgtaaatt gattctaagt attactgcaa tttctgtatt tataagcatt
     3781 ttatattgtc tgtttgctac tccaatttat caagctgatg ctttaattca agttgaacaa
     3841 aagcaaggta atacaatact tgagagtttg agtcaggttc ttccagatgc acaacctcaa
     3901 tcagcacctg aaatatcatt gcttcagtca aggatggtat taggtaaaac agtagacgat
     3961 c
//
LOCUS       DACAOP010000197         3831 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.198, whole genome shotgun sequence.
ACCESSION   DACAOP010000197 DACAOP010000000
VERSION     DACAOP010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3831
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.198"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(150..404)
                     /gene="bssS"
                     /locus_tag="IT892_004460"
     CDS             complement(150..404)
                     /gene="bssS"
                     /locus_tag="IT892_004460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415578.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssS"
                     /protein_id="HAP3137572.1"
                     /translation="MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNKSEQEGT
                     EVGQTLWLTTDVARQFISILEAGIAKIESGDFQVNEYRRH"
     gene            complement(692..937)
                     /gene="dinI"
                     /locus_tag="IT892_004461"
     CDS             complement(692..937)
                     /gene="dinI"
                     /locus_tag="IT892_004461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein I"
                     /protein_id="HAP3137573.1"
                     /translation="MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRY
                     AAANNLSVIGATKEDKQRISEILQETWESADDWFVSE"
     gene            complement(1011..2057)
                     /gene="pyrC"
                     /locus_tag="IT892_004462"
     CDS             complement(1011..2057)
                     /gene="pyrC"
                     /locus_tag="IT892_004462"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAP3137574.1"
                     /translation="MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMP
                     NLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAA
                     KLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIES
                     VMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRP
                     HLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTAL
                     GSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLV
                     PFLAGETVRWSVKQ"
     gene            complement(2163..2723)
                     /locus_tag="IT892_004463"
     CDS             complement(2163..2723)
                     /locus_tag="IT892_004463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP3137575.1"
                     /translation="MNKFLFAAALIVSGLLVGCNQLTQYTITEQEINQSLAKHNNFSK
                     DIGLPGVADAHIVLTNLTSQIGREEPNKVTLTGDANLDMNSLFGSQKATMKLKLKALP
                     VFDKEKGAIFLKEMEVVDATVQPEKMQTVMQTLLPYLNQALRNYFNQQPAYVLREDGS
                     QGEAMAKKLAKGIEVKPGEIVIPFTD"
     gene            complement(2857..3504)
                     /gene="grxB"
                     /locus_tag="IT892_004464"
     CDS             complement(2857..3504)
                     /gene="grxB"
                     /locus_tag="IT892_004464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 2"
                     /protein_id="HAP3137576.1"
                     /translation="MKLYIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVG
                     QKQVPILQKDDSRYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLL
                     PRFAKSAFDEFSTPAARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVK
                     PNAVNGELSEDDIQLFPLLRNLTLVAGINWPSRVADYRDNMAKQTQINLLSSMAI"
     gene            complement(3568..>3831)
                     /locus_tag="IT892_004465"
     CDS             complement(3568..>3831)
                     /locus_tag="IT892_004465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706986.2"
                     /note="Confers resistance to norfloxacin and enoxacin;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter MdtH"
                     /protein_id="HAP3137577.1"
                     /translation="PARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDL
                     GKSAHQPELPWMMLGIIGIFTFLALGWQFSQKRAARRLLERDA"
BASE COUNT          961 a          913 c          950 g         1007 t
ORIGIN      
        1 gaaccgctgc caataatgat gagatcgtat ttcatttttt tctctctgct ctcatggttt
       61 aagcagagta attaactgaa tgcagatata caacccagaa atggtaaagg caccggtgag
      121 gtgccttttg ggtggatggt catgtcatgt taatgacgcc gatactcgtt tacctggaaa
      181 tcaccggatt caattttggc gattcctgct tctaatatcg aaataaattg tctggcaaca
      241 tcagtggtta accagagcgt ctgaccaact tcagtccctt cctgctcgga cttatttggg
      301 gtctggtagt gcaaacgcaa catcagcgca tcatagctat caacggtgct gatgtcccac
      361 cctacgagcg gatgagtctg aatgacttca ttattttttt ccatcatggc cccctaattc
      421 gtgttactag acaacgttat tcgaggttca atgcgttttt atctgaagca acttcagtat
      481 accaataagt aagggtattc accgaatttt taaaggggga aacagataaa tttctgcttt
      541 taagatttat atgaacaata aaacagcatg tcattcatat ttttttagca tattgtgcaa
      601 ttattttgag gaagtgtaga aattttgtac tcaaaattcg taagtaaaat aaaaaagccg
      661 gggcgacccg gcaaaaaaaa atcactgcat attattcgct gacaaaccag tcatcggcgc
      721 tttcccacgt ttcctggaga atttcactaa tgcgctgttt atcttctttt gtcgcgccaa
      781 taaccgataa attattcgct gcggcataac gtaccgatac gtggccttca ttatcaggaa
      841 acgcatactg aatacggcgg gaaagttcgc cagccagggc gtcaatagcc ccagctggca
      901 atggagaagt tttcgctatg gtgacttcaa ttcgcataat agccccctgt tgaatatact
      961 ggttatttat acaggtaaaa taacctaatg acaacaggaa gctacgattt ttattgttta
     1021 acggaccagc gtaccgtttc cccggcgagg aatggcacca gcgtgtcatc agtcagtgcg
     1081 atgctttcag caacctgttg ctcttcacgt accagttcga tgaatgtgtc gttgaccggc
     1141 aacccataga actgcgggcc gtttacagaa cagaatgctt caaagtgctg caaagcattc
     1201 atttcttcaa agacggtagc gtaactgccc agtgcggttg gggcgttgaa gcagcccgcg
     1261 cagccgcaac tgctctcttt gcgatgacgt gcatgtggcg cagaatccgt accgaggaat
     1321 actcgattaa aaccgctggc gaccagttca cgcaatgcct gttggtgaat attacgtttg
     1381 aggatgggta gacaatacag gtgcggacgc acgcctccaa ccagcatatg gttgcggtta
     1441 aacatcagat gctgcggagt gatggtggca gccagccgtt catttccgtc acggacatag
     1501 tcggcagcat ctttggtggt gatgtgctca aaaacgactt tcagcgcagt caggcgctgg
     1561 cgcagaggtt ccatcacgct ttctataaag cgcgcttcac gatcaaaaat gtcgatatct
     1621 gcatgtgtca cttcaccatg caccagtagc ggcataccga ttttttccat gcgctcaagt
     1681 accggcatga ttgcgtcaat tgacgtcacg ccgtggctgg agttagtggt tgcgtttgcc
     1741 gggtaaagtt ttgcagcggt gaacacgcct tcgttaaatc cgcgctccag ctcattagga
     1801 tccagcgaat ctgttaaata acaggtcatc aatggggtga aatcgtgccc ggcaggtacg
     1861 gcgtcaagaa tacgctggcg atacgccacg gcagcctcaa cggtggtcac gggcggagcc
     1921 agattgggca ttacgatagc ccgtccataa atttcgctgg tatatggcac gacagttttt
     1981 aacatgtcgc catcgcggag gtgaaggtgc cagtcgtctg ggcggcggat ctttaatacc
     2041 tgggatggtg cagtcattaa tctctatgct ccggctgaag ggatgttttt gccggacaca
     2101 aaggataagc ggaaacgttt tcctttgcac gaaaaataaa gggcgcgaat gcgccctcgt
     2161 gattaatcag taaatggaat gacaatttcg cctggcttca cttcaatgcc tttcgccagt
     2221 tttttcgcca ttgcttcgcc ctggctgcca tcttcgcgca ggacgtaagc aggttgctgg
     2281 ttaaagtaat tgcgtaatgc ctggttcaaa tagggaagca acgtttgcat caccgtttgc
     2341 attttttccg gttgtaccgt cgcatcgacc acttccatct ctttcaggaa gatcgcacct
     2401 ttttctttat caaacacggg cagcgctttc agcttcagtt tcatggtcgc tttctgacta
     2461 ccgaacaggg agttcatgtc cagattggcg tctccggtta gggtaacctt attcggctct
     2521 tcgcgaccaa tttggctggt caggtttgtc agaacaatat gggcgtcagc cacgccgggt
     2581 aaaccgatat cttttgagaa attattatgt ttcgcaagcg actggttaat ttcttgttcg
     2641 gtgatggtgt attgggtgag ttgattacag ccaacgagca ggccactgac gatcaatgca
     2701 gcggcaaata aaaacttgtt catggtagtc ctcgacatga aatctgcgtc aatatcctga
     2761 cacaacgcag catgtgtcac cagcgataaa ctcgccagca gaaaaaactg aaaacggcgg
     2821 caacccgcga atacaggctg ccgcggcggg tcaggattaa atcgccattg atgataacaa
     2881 attgatttgt gtctgtttcg ccatattatc gcggtaatca gcaacgcggc ttggccagtt
     2941 aattccggct accagcgtca gattacgcag tagcgggaat agctgaatat catcttccga
     3001 aagttcgcca ttcacggcgt tcggtttgac gatcagtttg tccagcgcac gtaaatcatc
     3061 gctgatattc ttaatcagac cgtcagagtg ggccagcagg tcggcaaaat tacccgcgct
     3121 ggcctctttc ttgtcgacga aatatttgcg cgcggcggga gtagaaaact catcaaatgc
     3181 cgatttggca aaacgcggca acagcagttt gttggcgtag ccattgacct tgcgcagcca
     3241 ctcttcaatg gcaggggaac gtttgccggt cagtaacggt ttgccgtcga gtttatcgac
     3301 atagtgaacg atgtccatgc tttctggcat atagcggctg tcatcttttt gcagaatggg
     3361 aacctgtttt tgaccgacca tccgggtggg tgtttctgcg tcgtcgttga gcagaacatg
     3421 taattcgacg gggatatttt tcaggccgaa aatcatgcgg gctttgaggc agtaagggca
     3481 gtgatcgtaa atgtatagct tcacgtgact cctccatttg gctgtcagtt cactttcagt
     3541 atgaaggagt caggggggag tatcaaatca ggcgtcgcgt tcaagcaaac gacgcgcggc
     3601 gcgtttctgg ctaaactgcc aacccagcgc aaggaaagtg aagatgccaa taatgcccag
     3661 catcatccac ggaagctctg gctggtgcgc cgatttgccc aggtcaaaca gccagccgcc
     3721 accgatataa ccaatagcgc cgccaatcgc cagacccaga cggctaaacc ccatatagct
     3781 gccgcgagct cttgcgtccg ccagcgaagc acttaaggtt tcacgcgcag g
//
LOCUS       DACAOP010000198         3795 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.199, whole genome shotgun sequence.
ACCESSION   DACAOP010000198 DACAOP010000000
VERSION     DACAOP010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3795
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.199"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..478
                     /locus_tag="IT892_004466"
     CDS             <1..478
                     /locus_tag="IT892_004466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP3137578.1"
                     /translation="IFILGEFAGGMMGSELIKWVKSHKIDAHIITFVAKMPYIDSIKL
                     LEAGAKGCVWKTSHPAKLNRAIDSISNGYTYFDSVHMDCEKISSRYSSDNQLTNRESE
                     ILQLIADGKTNKEIANFLQLSRKTVETHRLNIMKKLDVHSGIELIKTALRMGVCTI"
     gene            complement(498..1001)
                     /locus_tag="IT892_004467"
     CDS             complement(498..1001)
                     /locus_tag="IT892_004467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001695307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HAP3137579.1"
                     /translation="MRLPKVKILAIFMFSILITKMSFASSACFNEAGSIFRIEPNLIK
                     AIALVESNLKNDSIGKNRDKKNNIKSFDYGLMQINQMHIPMLKKRGIIKDEQDLLDNP
                     CLNIKIGTEILYNHFSRCGVTWQCLGTYNAGFAMENQKKRLQYAKKIYVVYTRLNEID
                     KRKALAK"
     gene            complement(1085..1303)
                     /locus_tag="IT892_004468"
     CDS             complement(1085..1303)
                     /locus_tag="IT892_004468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137580.1"
                     /translation="MTNPINMNNFSQSLNIATATGDEVVSLDKHITTSATDTDQIQAF
                     IVSTWMASFQNDMYSKDNPIFPYYELEW"
     gene            complement(1470..2846)
                     /gene="ygeH"
                     /locus_tag="IT892_004469"
     CDS             complement(1470..2846)
                     /gene="ygeH"
                     /locus_tag="IT892_004469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HilA family transcriptional regulator YgeH"
                     /protein_id="HAP3137581.1"
                     /translation="MDLENKFSYHFLEGLTLTEDGILTQGNEQIYIPPKELGVLIVLL
                     ESAGHVVLKDMIIESVWKNIIVSDESLTRCIYSLRCIFEKIGYARCIETIYRKGYRFS
                     GQVFKTKINEDNTSDYSIAIFPFTTSLNTLDPLILNQELVQNISNKKIDGLYTYPMAA
                     TNFCNDHISQNSFLRRFKPDYFVTGRINQNNAVKTLYIELIDAKNLFLIASNHLPVDE
                     LHNTSQFIIDNILQTVHIPERSVRLAKPDQGYKNHYLSDELLAGKKELYEFTPESIYR
                     AMAIFDGLQNKSDIQTLKIECYCLLAECHMSLALHGKYELELAAQKALELLHYVSDIT
                     NVDGKILAIMGLITGLSGQAKVSHILFEQAKIHTTDIASLYYYRALVNFHNERIEEAR
                     ICIDKSLQLEPRRRKAVVIKECVDMYVPNPLKSNMKLYYKETSSESHRVIIDNILKLK
                     QLTRICMR"
     gene            complement(3181..3672)
                     /locus_tag="IT892_004470"
     CDS             complement(3181..3672)
                     /locus_tag="IT892_004470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP3137582.1"
                     /translation="MSTDTLEIFNNSDEWASQLKHALSQGENLALLHGLTPDILDRIY
                     AYAFDYHEKGNITDAEIYYKFLCIYAFENHEYLKGFASVCQSKKKYQQAYDLYKLSYN
                     YSPYDDYSVIYRMGQCQIGAKNIDNAMQCFYHIINNCEDESVKSKAQAYIELLTDNSE
                     DNG"
BASE COUNT         1167 a          623 c          641 g         1364 t
ORIGIN      
        1 aatatttatt ttaggagaat ttgcaggtgg aatgatgggg tccgaactca ttaaatgggt
       61 taaatcgcat aaaatagatg ctcatattat tacatttgta gcaaaaatgc cgtatattga
      121 ttcaataaaa ttgcttgaag ccggtgcaaa aggatgcgta tggaaaacca gtcacccggc
      181 gaaactaaat cgggctattg attcgattag taatggttac acttattttg atagtgtaca
      241 catggattgt gaaaaaatat cttcaagata ttcctctgat aatcaactta caaatcgtga
      301 gtctgaaata ctacaactca tagctgatgg aaaaacaaac aaagaaatcg ctaatttctt
      361 gcagttaagc aggaaaacag tcgaaacaca tagactcaat atcatgaaga aattagatgt
      421 tcacagtggt atcgagttga tcaaaacagc tttacgtatg ggcgtttgca ctatataaaa
      481 aaaaagaggc tttaggctca ttttgctaaa gccttacgct tgtctatttc attaagtctg
      541 gtatatacaa catatatttt ttttgcatat tgcagcctct ttttttggtt ttccattgca
      601 aaacccgcgt tataagtccc cagacattgc cacgttactc cacaacgtga aaaatgatta
      661 tataaaatct cggtccctat tttaatgttt agacaggggt tatctaacaa atcttgttca
      721 tcttttatta ttccacgttt ttttaacatg ggaatgtgca tctggtttat ctgcattaaa
      781 ccataatcaa aactctttat attgtttttc ttatccctgt tcttgccgat gctatcattt
      841 tttaaattac tttcaacaag tgcgatagct ttgatcaaat ttggttcgat tctgaaaatt
      901 gatcctgctt cattaaagca agcgctactg gcgaaagaca tttttgtaat taatatagaa
      961 aacatgaaga tggctaagat tttaactttg ggtaagcgca tatgttttta tgtgtaggat
     1021 tgaaggaaag gaacgagata ctaatatatt cagtatctcg ttaatcattt aagtggtcaa
     1081 ttatctacca ttccagttca tagtaaggaa agataggatt atctttcgaa tacatatcat
     1141 tttgaaaaga tgccatccat gttgaaacta taaatgcttg tatttgatct gtatcagtag
     1201 cactggtggt gatgtgttta tctaatgaaa cgacttcatc acccgttgcg gttgctatat
     1261 ttaaactttg agaaaaatta ttcatattga ttggattagt cataaagttc ccttttttat
     1321 ttgtccaggc caatagccca tacacaatac ttttaatcta gagtatttga tatatattgc
     1381 aataaggtaa ttatcttaga tgttttcatc tctgttgttt acataaccag ttgcatacat
     1441 ctaaacaata aaattgcgac aataaatatt tatcgcatac aaattctcgt cagttgcttt
     1501 agtttcaaaa tgttatcaat tataactcga tggctttcac tcgaagtttc tttatagtag
     1561 agtttcatgt tgcttttgag cgggttaggc acatacatat ctacacactc ttttatcaca
     1621 actgcttttc gtcttctggg ttcgagttgt agtgatttgt ctatacaaat ccttgcctct
     1681 tcaattcttt cattatgaaa gttgacaagt gctctatagt agtagagaga ggctatatca
     1741 gttgtgtgta tcttagcctg ttcaaataag atatgagata cttttgcttg tccagacaga
     1801 ccagttatca gtcccataat ggctaaaatt tttccatcga cattggttat gtctgataca
     1861 taatgtaaaa gctctaatgc tttttgagca gcaagttcaa gttcatactt tccatgaagt
     1921 gccaaagaca tatggcattc cgctagcaga caataacatt ctatttttag cgtctgtata
     1981 tcacttttat tttgtaatcc atcaaatata gccatagccc tgtaaatgct ttcaggagta
     2041 aactcgtaaa gttctttctt accagccaac agttcatctg ataaataatg attcttgtaa
     2101 ccttggtccg gtttagctaa tcttacagaa cgctctggaa tatgtaccgt ttgaaggata
     2161 ttatctataa taaattgtga tgtgttatgt agttcatcaa caggaagatg attactggcg
     2221 atgaggaaaa gatttttagc gtcgatcagt tcaatgtata aagttttcac cgcgttattc
     2281 tggtttattc ttcctgtaac gaaataatct ggcttgaatc ttctcaaaaa tgaattttgc
     2341 gatatgtgat cattacaaaa atttgtcgca gccatcggat aggtataaag gccatcgatt
     2401 tttttattcg aaatgttttg cactaattcc tgattaagta ttaatggatc cagagtattc
     2461 aatgaagtgg tgaaaggaaa tatagctatg gaatagtctg aagtgttatc ttcatttatt
     2521 ttagttttga aaacctgtcc actgaaacga taccctttcc ggtagattgt ttctatgcaa
     2581 cgagcatagc caattttttc aaaaatgcag cgcaaagaat agatacatct tgtcagggac
     2641 tcgtcactta caataatatt tttccatact gattcgatga tcatatcttt caggacaaca
     2701 tgaccagcgg attcaagtaa tacgatcaat actcctaact ctttcggtgg aatataaatc
     2761 tgctcatttc cttgagtaag aattccatct tccgtgagcg ttaatccctc gagaaaatga
     2821 tatgagaatt tattttctaa gtccattagt taacctctat gaaaaaattg gtttcttgca
     2881 tcctgcataa gcaatagaaa ttgtggctat tcatatttat gtgtcattaa tgctacagga
     2941 gtttacattc gacatatcta tggttgtgtt cactaattta tcttaggaat tcagtgatgt
     3001 aatctgaaat agccttattc aattttgata aaatagattg ttctctaacg cgttgaaaaa
     3061 taataattta tagtgtgttc ttaactgttt taagatgttg atttaagaaa acataagaga
     3121 agctggtcat agtagttaac tgcactataa ccagcaattt taaccaaaag attgtaatgc
     3181 ttagccatta tcttctgaat tatcagttaa gagttcaata tatgcctgcg ctttgctctt
     3241 aacactttca tcctcacaat tgttaataat atgatagaaa cattgcattg cgttatcgat
     3301 atttttagcc ccaatttgac attgacccat acgataaata actgaatagt catcatacgg
     3361 tgagtaattg taacttagtt tgtaaaggtc atatgcttgt tgatatttct tttttgactg
     3421 gcatactgat gcaaaacctt ttagatattc atgattttcg aacgcataaa tgcacagaaa
     3481 tttataataa atttctgcgt ccgttatatt acctttttca tggtagtcga atgcatatgc
     3541 atatattcta tcaaggatat caggagtcaa tccatgtagt aatgccagat tttctccttg
     3601 tgataatgcg tgttttagtt gacttgccca ttcatcactg ttattgaata tttcaagtgt
     3661 atctgtgctc ataatattcc tctgtgatgt gtttcgtgat gctaaattat tattgattga
     3721 ctcattaatt ttttgcattt atcttttttg aattatgagt tttaagcttg cattgcttat
     3781 gggtatattg gttca
//
LOCUS       DACAOP010000199         3745 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.200, whole genome shotgun sequence.
ACCESSION   DACAOP010000199 DACAOP010000000
VERSION     DACAOP010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3745
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.200"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..2066)
                     /gene="htrE"
                     /locus_tag="IT892_004471"
     CDS             complement(<1..2066)
                     /gene="htrE"
                     /locus_tag="IT892_004471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Yad fimbria usher protein HtrE"
                     /protein_id="HAP3137583.1"
                     /translation="MTIEYTKNYHHLTRIATFCALLYCNTAFSAELVEYDHTFLMGQN
                     ASNIDLSRYSEGNPAIPGVYDVSVYVNDQPIINQSITFVAIEGKKNAQACITLKNLLQ
                     FHINSPDINNEKAVLLARDETLGNCLNLTEIIPQASVRYDVNDQRLDIDVPQAWVMKN
                     YQNYVDPSLWENGINAAMLSYNLNGYHSETPGRKNESIYAAFNGGMNLGAWRLRASGN
                     YNWMTDSGSNYDFKNRYVQRDIASLRSQLILGESYTTGETFDSVSIRGIRLYSDSRML
                     PPTLASFAPIIHGVANTNAKVTITQGGYKIYETTVPPGAFVIDDLSPSGYGSDLIVTI
                     EESDGSKRTFSQPFSSVVQMLRPGVGRWDISGGQVLKDDIQDEPNLFQASYYYGLNNY
                     LTGYTGIQITDNNYTAGLLGLGLNTSVGAFSFDVTHSNVRIPDDKTYQGQSYRVSWNK
                     LFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVKHPEQDLEPKFMRNYSRMKNQVTV
                     SINQPLKFEKKDYGSFYLSGSWSDYWASGQNRSNYSIGYSNSTSWGSYSVSAQRSWNE
                     DGDTDDSVYLSFTIPIEKLLGTEQRTSGFQSIDTQISSDFKGNNQLNVSSSGYSDNAR
                     VSYSVNTGYTMNKASKDLSYVGGYASYESPWGTLAGSISANSDNSRQVSLSTDGGFVL
                     HSGGLT"
     gene            complement(2101..2841)
                     /locus_tag="IT892_004472"
     CDS             complement(2101..2841)
                     /locus_tag="IT892_004472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HAP3137584.1"
                     /translation="MFFNTKHTTALCFVTCMAFSSSSIADIVISGTRVIYKSDQKSVN
                     VRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKHGQTIKLMYTAST
                     SLPKDRESVFWFNVLEVPPKPDAEKVANQSLLQLAFRTRIKLFYRPDGLKGNPSEAPL
                     ALKWFWSGSEGKASLRVTNPTPYYVSFSSGDLEASGKRYPIDVKMIAPFSDEVMKVNG
                     LNGKANSAKVHFYAINDFGGAIEGNARL"
     gene            complement(2939..3523)
                     /locus_tag="IT892_004473"
     CDS             complement(2939..3523)
                     /locus_tag="IT892_004473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HAP3137585.1"
                     /translation="MSKKLGFALSGLMLAMVAGTASADMDGGQLNISGLVVDNTCETR
                     VDGGNKDGLILLQTATVGEIDAGVLNDTVGAKAKPFSITVDCSKANPNPGSTAKMTFG
                     SVFFGNSKGTLNNDMSINNPSDGVNIALHNIDGSTIKQVQINNPGDVYTKALDATTKS
                     AVYDFKASYVRAVADQTATAGYVKTNTAYTITYQ"
BASE COUNT         1079 a          805 c          784 g         1077 t
ORIGIN      
        1 aaagtcagtc caccgctatg caatacaaaa ccaccgtcgg tgctgagaga aacttgacgg
       61 ctgttatcgc tatttgcaga aattgaacct gccagcgttc cccatggtga ctcatagctg
      121 gcataacccc caacataact caaatctttg ctggctttat tcatcgtata gccagtattc
      181 acgctataac tgacgcgagc gttatcgcta tagccactgc tgctaacgtt gagttggtta
      241 ttacccttaa agtcactgct tatttgagta tcaatactct ggaaacctga agtacgttgt
      301 tcagtgccaa gtaatttttc aattggaatg gtgaaactaa gataaacgct atcgtcagtg
      361 tcgccgtctt cattccatga acgctgggca ctgacactgt agctgcccca ggatgtactg
      421 ttactgtagc caatagagta attgctacga ttttgtccgg aagcccagta atcggaccaa
      481 cttccggaaa gataaaatga accgtaatct tttttctcaa atttcaacgg ttggttaata
      541 ctgaccgtaa cctgattttt catgcgtgag taattacgca tgaatttcgg ttcaagatct
      601 tgttcgggat gtttcacttc atcaattaga gttagtgcat cattaagacc aaggtaattc
      661 tgtgtcgaat agcgataggc cgcgatattc agtgaagtac ttgtttcttc gaataacttg
      721 ttccaggaaa cacgataact ttgcccctgg tatgttttat catccgggat acgaacattg
      781 gaatgagtca catcgaaaga aaatgcacca actgaagtat tcagaccaag acctaacaaa
      841 ccagcggtat agttattatc ggttatctga ataccggtat aacccgtcag atagttattc
      901 aggccgtagt agtagcttgc ttgaaataaa ttaggctcat cctgaatatc atcttttaag
      961 acctgaccgc cgctaatatc ccaacgtcca acgccagggc gtaacatttg aacaacggat
     1021 gagaaaggtt gcgagaatgt ccgctttgag ccatcggatt cttcgatggt aacaataaga
     1081 tcgctgccgt accctgacgg actcagatca tcaatgacga aagcgcctgg cggcaccgtc
     1141 gtttcataaa tcttatagcc accttgcgta atagtgactt tggcgttggt attggcaacg
     1201 ccatgaatga taggcgcaaa gctggctaaa gtcggaggca acatgcggct gtcactgtat
     1261 aaacgaatgc ctcggatact gacggaatca aaggtttcgc ccgtcgtata agactcacca
     1321 agaatgagtt gagaacgcag cgaggcgata tcacgctgaa cataccgatt cttaaaatca
     1381 taattactgc cagaatcggt catccagttg tagttgcccg aggcacgcag tcgccatgca
     1441 cctaaattca tcccaccgtt aaatgcagca taaatgcttt cattttttcg accaggggtt
     1501 tcactatgat atccgttgag gttgtatgac aacatggccg cattaatgcc gttttcccat
     1561 aacgatggat caacatagtt ttggtaattt ttcattaccc aggcttgagg aacgtctata
     1621 tccagacgtt gatcgttaac gtcataacga acagaagcct gagggataat ttccgtcaaa
     1681 ttgaggcaat tgccgagcgt ttcatccctg gcaagcagaa cggctttttc gttatttata
     1741 tcgggagaat taatatgaaa ctgcaataaa ttctttaatg tgatacaagc ctgggcgttc
     1801 ttttttcctt caattgcgac aaatgtaata ctttggttaa tgattggttg gtcgtttaca
     1861 taaacactga cgtcgtaaac acccggtata gcggggttac cttcactgta ccggctgaga
     1921 tcaatattag atgcattctg ccccatcagg aaggtatggt catattcaac gagttcagca
     1981 ctgaaagcag tattgcaata cagcagcgcg caaaacgtgg cgatacgggt cagatgatga
     2041 taatttttag tatattctat agtcacgcta tgcttcctgc ggaattatat ccttgcctga
     2101 ttacagcctg gcattacctt caattgcgcc accaaagtca ttaatggcgt aaaaatgcac
     2161 ttttgcagaa ttcgctttgc cattaaggcc attgactttc atgacctcat cactaaatgg
     2221 tgcaatcatt ttcacatcaa tcggatagcg tttaccgcta gcttctaaat caccactgct
     2281 aaaagagacg tagtaagggg ttggattggt cactcgtaat gacgccttac cttctgaacc
     2341 tgaccagaac cacttcaggg ctaacggggc ttcagaggga tttcccttca atccatccgg
     2401 gcgatagaaa agttttatac gtgtgcgaaa tgccagttgc agcaggcttt gattcgcgac
     2461 cttttctgca tctggttttg gtggaacttc cagtacgtta aaccagaaca cgctctctct
     2521 gtctttaggc agtgaggtgc tggctgtgta cattaatttg attgtttgcc catgtttggc
     2581 atcaatacgc gatactggcg gcgtagcagt aaaagggact gtaatactgc caggctcagc
     2641 gttgtcatcg ccagtatcta accaactctg gacaagcaac gggttattcc ctttattttc
     2701 cagacgtacg ttgacacttt tttgatcgct tttatatatt acgcgagtac ccgaaatgac
     2761 aatgtccgca atagacgatg aactaaaagc catacaggtt acgaagcata aagctgttgt
     2821 atgtttggtg ttaaaaaaca taaaccatcc ctgatagagt taattaaaac agggaataat
     2881 ataaaataga aattattatt ccctgtatat tcattcaatc aatttaactg gtgaatactt
     2941 actgataagt aatggtgtat gcagtgttag tttttacata accagcagtt gctgtttggt
     3001 ctgcgacggc acgaacgtaa gacgctttaa aatcataaac agcagatttt gtcgttgcat
     3061 ccagggcttt agtatacaca tcgccagggt tgttaatttg aacctgtttg atagtggaac
     3121 catcaatatt gtgtagagcg atattaacgc cgtcagatgg gttgttaata gacatgtcgt
     3181 tgttcaaagt ccctttgctg ttaccaaaga aaacagaacc gaaggtcatt ttagccgtgc
     3241 tacctggatt cggatttgct ttgctgcagt caacggtgat gctgaaaggt ttagctttag
     3301 cgccaacggt gtcattcagt acgccagcat cgatttcacc aacggttgcg gtttgcagca
     3361 ggatcagacc atccttgtta ccgccgtcaa cgcgggtttc acaggtgtta tcaacaacca
     3421 gaccactgat atttaactga ccgccgtcca tatcagcaga agcagtacct gcaaccatcg
     3481 ccagcataag accagacagg gcaaaaccta attttttaga cataaaaatc ctttaataaa
     3541 attccattag tcagactaca tgtttgaaga atgactattc atgacacaaa taggagaaac
     3601 aaatgttaga tattaatgag caatgatatt tgttacccaa atttacaacc attgttcatt
     3661 aggtcgccta ttgtgcactt tagaagcttt tgaacaaatt aaatttactt aattcaaaat
     3721 taagtaaaaa taagttcaca agtgc
//
LOCUS       DACAOP010000200         3741 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.201, whole genome shotgun sequence.
ACCESSION   DACAOP010000200 DACAOP010000000
VERSION     DACAOP010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3741
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.201"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..692
                     /locus_tag="IT892_004474"
     CDS             <1..692
                     /locus_tag="IT892_004474"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137586.1"
                     /translation="SKIVTYITLAVFSILVLIPINIENTEIAAHIGIIKISLTIVVLT
                     MFFIIGIVADKYESIIAAIMFVLLSLPFGHVLSNDSSIKKLTISMCENEKQAGIEKKP
                     YECEEIAKSSSKFESVFFTYGLIVMSLLLTNQYIASTRKVNLLLSIFEEEHSSTDEEQ
                     IKTKGRVASLVEKANKSCENPIVRVTTFIVGSILVLLIAFALMYYNHIEESKHIMSLR
                     ESLSVWAKLFN"
     gene            798..1064
                     /locus_tag="IT892_004475"
     CDS             798..1064
                     /locus_tag="IT892_004475"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137587.1"
                     /translation="MIKKRERETSLDDIDDTDWDEYENDETYVDPTTTSLTQEEDDKP
                     VSTIRILVFIIHLGLFKFAAMTLNGLIRSLAILHGLYIKTIKRL"
     gene            1163..1435
                     /locus_tag="IT892_004476"
     CDS             1163..1435
                     /locus_tag="IT892_004476"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137588.1"
                     /translation="MNRQQIAKLVAIPSKIKMIDTEINEYLFMVNKKNEGYFWINENS
                     ITTEMGRNEYIKVIKEANKYNLSCKYHIIAESFTYDSDNIHCIRIK"
     gene            1448..1729
                     /locus_tag="IT892_004477"
     CDS             1448..1729
                     /locus_tag="IT892_004477"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137589.1"
                     /translation="MNKTELTQRLYEADLINNYAITGSQESYLFMANQNGEGYYWINH
                     NGETLNFIKEDLDKIYSEAKEYGLSDKKFHVVSKSMVYEKQCSTIMINF"
     gene            1840..2484
                     /locus_tag="IT892_004478"
     CDS             1840..2484
                     /locus_tag="IT892_004478"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137590.1"
                     /translation="MGRNIESKSFVSIWKEVKSYTCTVNETETFEMLLLVMAGRGFKF
                     SKHEFIILSTRGQMRSQKVNRCSLHKKFFYKSVEEKMKTVFMALKQIHDRNELERSRL
                     LNGRDKIISRFNRIKTFNSIWKELIELEITTDEIDSYECLIFIMKDRKIKIPDSALAA
                     MELTAFNSLKKKKLYRETKSIPFELDSIREELNNIYNLLTDNIKYDKFQTIHTI"
     gene            2453..2854
                     /locus_tag="IT892_004479"
     CDS             2453..2854
                     /locus_tag="IT892_004479"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137591.1"
                     /translation="MTNFKRYTLYKGMVIIDKVATGKTNFLNRIVKDHPDSILNLDSD
                     FYFAGKSSYLSAINEAEEKGKFIIMSGSYIGDTEKSELVNKGYLVFHSITQAMFYYSE
                     HLSPESIARKEQQAIKQIMTGERITRKRNRL"
     gene            2866..3258
                     /locus_tag="IT892_004480"
     CDS             2866..3258
                     /locus_tag="IT892_004480"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137592.1"
                     /translation="MSNITLNTPYSGMIILDHYHSGKTTFLKKITSEHPDLFFNMDDN
                     YNNYTDSIIERAKANNQFLLAANRLLNEKEKKELLKKGFKILNSVEEAKSYYDNYLNP
                     MKIAKIEQQEIEQVMNEKPVAIKKKARL"
BASE COUNT         1488 a          523 c          659 g         1071 t
ORIGIN      
        1 taagtaaaat agtaacatat ataacattgg ctgtttttag tatattagtg ttgattccaa
       61 taaatataga aaatacagaa atcgccgctc atattgggat tattaagatt tccttaacaa
      121 tcgtagtgct tactatgttt tttattattg ggattgtagc ggataagtat gaaagtatca
      181 ttgcagcgat aatgtttgtg cttttatcat tgccttttgg tcatgtatta agtaatgact
      241 cttcgataaa gaaactaact atttcaatgt gcgaaaacga aaaacaagca ggaattgaaa
      301 aaaaaccata tgagtgcgag gaaattgcca agtcatcatc caaatttgaa agtgttttct
      361 ttacttacgg tttaattgta atgagtttac tattaacaaa tcaatatatt gcatctacac
      421 gaaaagtaaa tttattattg agcatttttg aagaagaaca ttcatcaacc gatgaagaac
      481 aaataaagac aaaaggaaga gttgccagct tagtagaaaa ggcaaataaa tcatgtgaaa
      541 atcctattgt aagagtaact acttttattg ttggttcaat cctggtttta ttaatagcat
      601 ttgcacttat gtactataac catattgaag aaagtaaaca tataatgtct ttgagggaaa
      661 gtttatctgt ttgggcgaaa ttatttaact aatgaattat aattaaaaaa ccacaaagga
      721 gttaacttat ggaatatata gtttaattta tgaagtggtt tatgatttga tccataaaaa
      781 caaaaaagga aaataaaatg ataaaaaaaa gagaacgaga aacttcatta gatgatatcg
      841 acgacactga ttgggacgaa tacgaaaatg acgaaacata tgttgaccct acaacaacct
      901 cactaaccca ggaagaagac gacaagccag taagcaccat tagaatctta gtatttatta
      961 tccacttagg actattcaaa tttgcagcta tgacattaaa cggcttaatc agatccctgg
     1021 ctattctgca tgggctatat atcaaaacaa taaaaagact ttaaatgtgg aaaaatagtg
     1081 aactctaacc ccagcttatt gacgatttcg ctggggtatt tatatttata ttacagggta
     1141 tataatataa atggggtgac ttatgaacag acaacaaatc gcaaaattag tagcaattcc
     1201 ttcaaagata aagatgatag ataccgaaat taatgaatat ctttttatgg ttaataaaaa
     1261 gaatgaaggg tatttctgga taaatgaaaa tagcattact actgaaatgg gcagaaatga
     1321 atatattaag gttataaaag aagctaacaa atacaatctt tcctgtaaat atcatatcat
     1381 agccgaaagt tttacttatg acagcgataa tattcattgc attagaataa aataaatggg
     1441 ggggcttatg aacaagacag aactaacaca gagactatat gaagctgatt tgataaataa
     1501 ctatgccatt accggaagcc aggagagtta tctctttatg gctaaccaga acggggaagg
     1561 gtactactgg ataaaccata atggcgagac actgaacttt ataaaagaag atctggacaa
     1621 aatttacagc gaagcaaaag agtatgggtt atcggataaa aaattccatg tggtttcaaa
     1681 aagcatggta tatgaaaaac agtgcagcac aataatgata aatttctaat tatggagaaa
     1741 aggtggagaa tttccccagc ttattgacag tttcactgta tccaataaat tgaaatagta
     1801 gtaataaaac aataaataat tataaccaag gagttaatta tgggaagaaa tatagaaagc
     1861 aaatcattcg tcagtatatg gaaagaagta aaaagctata cttgcactgt gaatgagaca
     1921 gaaacttttg aaatgctatt attagtaatg gctggtagag gttttaaatt ctctaagcat
     1981 gaatttataa ttctatcgac aagagggcaa atgagaagcc agaaagtaaa tagatgctca
     2041 ttacacaaga aattctttta caagtcagta gaagaaaaaa tgaagacggt attcatggca
     2101 ttaaagcaaa tccatgatag aaacgaactg gaaagaagta gactattaaa cggaagggat
     2161 aaaatcatta gccgtttcaa cagaatcaaa acctttaaca gtatctggaa ggaattaata
     2221 gaattagaga tcactactga cgagatagat agttatgaat gtcttatttt tattatgaag
     2281 gacagaaaaa ttaaaattcc tgactcagca ttagccgcta tggaactcac cgcctttaat
     2341 tctctcaaaa agaaaaagct gtacagggaa acaaaatcca ttccatttga actcgattct
     2401 atcagagaag aactaaataa tatatacaac ttacttacgg ataatattaa atatgacaaa
     2461 tttcaaacga tacacactat ataaaggaat ggtaattatt gataaggtag cgaccgggaa
     2521 aacaaatttt ctaaatcgta ttgttaaaga ccatccagac tcaattttaa acttagacag
     2581 tgatttttat ttcgctggta aatcttccta cttgtcagca ataaatgaag cagaagagaa
     2641 aggaaagttt attattatgt ctggtagcta tattggtgat acagaaaaga gtgaactggt
     2701 aaataaaggc tatctggtgt tccattcaat tactcaggcg atgttttact attcagaaca
     2761 tttaagccct gaatcaatag caagaaaaga acagcaagcc attaaacaaa taatgacggg
     2821 tgaaagaatc acccgtaaaa gaaacagact ataaggggta caaatatgag caatattact
     2881 ttaaacacac catattcagg aatgataata ttagatcatt accattcagg gaaaacaaca
     2941 tttttgaaga aaataacaag cgagcatcca gatttatttt ttaacatgga cgataattat
     3001 aataattaca ctgattctat aatagaaaga gcaaaagcaa ataatcaatt tttattggct
     3061 gctaatcgtt tattaaatga aaaagaaaaa aaggagcttc tgaagaaagg tttcaagata
     3121 ttaaattcag ttgaagaagc taagagttat tatgataact atctaaaccc tatgaagata
     3181 gccaaaatag aacagcaaga aattgagcag gtaatgaatg aaaaaccagt tgccattaag
     3241 aagaaagcca gattgtaata acctttaagc cttcccgttc gtggagggct tcttttttta
     3301 tccagtatcg tatgatcgcc aacaaaaaaa tcatggagaa ttaatggagc cttaccccag
     3361 cttattgaca gtgaaactgt atcttttata aatatataag agggtaaaat aactaaggag
     3421 ttaactatgg agataaaata taattgcaaa gaaatatttg aagagttaaa aagtgatggt
     3481 gttttggatt cattcgtcgc atggtcatca aatatatacc caaacataca tttaagtcag
     3541 ccatgtttcg aaagttgcta tgaaatatat aaattgaatg agaatttctt taaagaagaa
     3601 tggaataaaa aataatgtct acctaaccag acccgcataa cagcgggttt tcttttttta
     3661 atcaaagcta ttattcccca tgtgtttgca aacaaacccc cccaggatta gaagataaac
     3721 acagaggggg aataatgtcg t
//
LOCUS       DACAOP010000201         3739 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.202, whole genome shotgun sequence.
ACCESSION   DACAOP010000201 DACAOP010000000
VERSION     DACAOP010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3739
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.202"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            20..841
                     /locus_tag="IT892_004481"
     CDS             20..841
                     /locus_tag="IT892_004481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP3137593.1"
                     /translation="MFKANHVPVLMYHHVSHCPGLVTLSPETFRKQMKWLAENNWKTL
                     SSDELEFFYRGGKLPRKSVMLTFDDGYLDNWFQVYPLLNEFNLKAHIFLITSFIGNGP
                     VRHSPGKEYSHRDCEHQIATGNADNVMLRWSEVNEMLQSGLVEFHVHTHTHTRWDKKF
                     TSREEQCKHLRQDLLSGREYLKKMTGKCSKHLCWPEGYYNKDYIQIAEELGFHYLYTT
                     ERRMNAPAKGTTRIGRISTKERENCVWLKRRLFYYTTPFFSSLLALHKGPRLPDD"
     gene            844..1932
                     /gene="capU"
                     /locus_tag="IT892_004482"
     CDS             844..1932
                     /gene="capU"
                     /locus_tag="IT892_004482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative hexosyltransferase CapU"
                     /protein_id="HAP3137594.1"
                     /translation="MNILFTESSPNIGGQELQAVAQMKALKKMGHSVLLVCRENSKIA
                     FEASKFGIDITFALFRNSLHIPTVWRLLGIVHSFQPDAIVCHSGHDSNIVGLVRFFTW
                     KHPFRIIRQKTYLTRKTKFFSINHFCDEVIVPGTNMKTHLEQEGCRTRVTVVPPGFDF
                     QELYVDSRNSLPPSVLSWLASRRGCPVIAQVGMLRPEKGHEFMLNLLFHLKMNGRQFC
                     WLIVGSGSPELREHLQYQIDSMGMHDDVFIADNVFPAAPVYRVASLVVLPSENESFGM
                     VLAEASAFSVPVVATQIGGIPEVIQNNQTGTLLPASNKHAWMCALNDFFNDPGRFYQM
                     ARLAKQDIEERFDINKTALKILTLAKQK"
     gene            1937..2887
                     /gene="virK"
                     /locus_tag="IT892_004483"
     CDS             1937..2887
                     /gene="virK"
                     /locus_tag="IT892_004483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor VirK"
                     /protein_id="HAP3137595.1"
                     /translation="MFSISNLSFIGFLKRIIFSSDSLPGKWEHRKFRFMYILRCSINP
                     VVSIRYYYELRSLPCIEDILAIHPTLPARIHRPYLHKGGRAWTRGQYILEHYRFVQNL
                     PEKYSKFLFPQKSVSLVQFIGKDGENFDIQCSPSGFDREGELMLSLFYNKTVIARLTF
                     SVILTQNGHIAFIGGLQGAPKNTGPDVIRCATRACYGIFPKRIIFEAFCALMKACNIS
                     ECLAVSEHSHVFRQLRYWYQKRKTFVAVYSDFWESVAGKTCGDWYRLPTQVIRKPLSD
                     IASKKRSEYRKRYALLDYIHETTISSLDAYPVHSEHQNLN"
     gene            2952..>3739
                     /gene="lpxM"
                     /locus_tag="IT892_004484"
                     /gene_synonym="msbB"
     CDS             2952..>3739
                     /gene="lpxM"
                     /locus_tag="IT892_004484"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858371.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HAP3137596.1"
                     /translation="MKKYKSEFIPEFKKNYLSPVYWSTWFLLGMIAGISMFPPSFRDP
                     VLAKIGRWAGRLSKKARRRATINLSLCFPEKSDTEREIIVDKMFITALQSIVMMAELA
                     IRGPEKFQKRVFWKGLEILEEIRHNNRNVIFLVPHGWSVDIPAMLLAAQGKKMAAMFH
                     QQRNPVIDYVWNSVRRKFGGRLHAREDGIKPFIQSVRQGYWGYYLPDQDHGPEYSEFA
                     DFFATYKATLPIIGRLMNISQAMIIPLFPVYDEKKHLLTIEIRPP"
BASE COUNT         1090 a          695 c          841 g         1113 t
ORIGIN      
        1 tttaaacgga gggggcattt tgtttaaagc aaatcatgtt ccggtattaa tgtatcatca
       61 tgtcagccat tgcccaggac tggttacact ttctcccgag acattccgga aacaaatgaa
      121 atggttggct gaaaacaact ggaaaacact gtcatcagat gaactggagt ttttttatcg
      181 gggcggaaaa cttccccgta aaagcgttat gttgacattt gatgatggat accttgacaa
      241 ctggtttcag gtatatcctt tattaaacga gtttaatctc aaggcacata tttttttaat
      301 taccagtttt attggaaatg gtccggttcg tcactctcct ggaaaggaat attctcatcg
      361 cgattgcgaa catcaaatag caaccgggaa tgctgataat gttatgcttc gctggtctga
      421 agtgaacgaa atgttgcaat ctggtctggt cgaatttcat gttcatacac atactcatac
      481 acgttgggat aaaaagttca cttcacgaga agaacagtgt aaacatcttc ggcaggactt
      541 attgagcggg agagaatatt taaaaaaaat gacaggaaaa tgcagtaaac atttgtgttg
      601 gccggaaggt tattataaca aggattatat tcagatcgct gaagaacttg gattccatta
      661 tttatataca acagaaagaa gaatgaatgc tcctgctaaa ggaactacac ggataggaag
      721 aataagcacc aaggaacggg aaaattgcgt atggctgaaa agacgacttt tttattatac
      781 aacaccgttt ttttcatcgt tgctggccct tcataagggg ccaagattac cggatgacta
      841 ataatgaata tactatttac ggaatcatca ccgaatatag gtggtcagga attacaggct
      901 gttgctcaaa tgaaggccct gaagaaaatg gggcattcag ttctgcttgt ctgcagggag
      961 aacagcaaaa ttgcttttga agccagtaag tttggaattg atatcacatt cgcgttattt
     1021 cgaaacagtc ttcacattcc tactgtatgg agattactcg gaatagttca tagttttcag
     1081 cccgatgcaa tcgtttgtca cagtggacat gatagtaata ttgttggttt ggtacggttt
     1141 tttacctgga aacatccatt cagaattatc aggcaaaaga catatttgac acgaaaaaca
     1201 aaattttttt caataaatca tttttgcgat gaggtgattg ttcccggaac aaatatgaag
     1261 acacatctgg agcaggaagg atgtcgaact cgggttactg ttgtgcctcc tggctttgat
     1321 ttccaggaat tatacgttga ttcccgaaac agtttgcctc cgagtgttct ttcctggctg
     1381 gcgtcccgaa gaggatgccc cgtaattgct caggtaggaa tgttgcgccc ggaaaaaggg
     1441 cacgaattta tgttgaattt actgttccat ttaaaaatga atggacgaca gttctgttgg
     1501 ttgattgtgg ggtctggttc acctgaactg cgggaacatt tacagtatca gattgacagt
     1561 atgggcatgc atgatgatgt ttttattgct gacaatgttt ttcctgccgc ccccgtatat
     1621 cgggttgcca gtctggtggt tctgccttca gaaaacgaat cttttggtat ggtgctggca
     1681 gaagcatcgg cattttctgt gcctgtagtg gccactcaga ttggtggaat ccctgaggtt
     1741 attcagaaca accagaccgg gacattgtta ccagcaagta ataagcacgc atggatgtgc
     1801 gccctgaatg atttttttaa tgaccctggg cgtttttatc agatggctcg cctggcaaaa
     1861 caggatatag aagagcggtt tgatattaat aaaactgcgt taaaaatact cacattagcg
     1921 aagcaaaagt aacaatatgt tttctataag taacttatca tttatcggtt tccttaaaag
     1981 gattattttt tcctcagatt cactaccggg gaagtgggaa cacagaaaat ttcggttcat
     2041 gtacattttg cgatgttcta taaatccggt tgtcagtatt cgatattatt atgaactgcg
     2101 ttccttgccg tgcattgagg atattctggc aatacacccc acgttgccag caagaattca
     2161 tcgcccttat ttgcataaag gggggcgcgc ctggacccgt ggacaatata ttcttgagca
     2221 ttatcgcttt gtgcaaaatt tgccagaaaa atattctaaa tttttgtttc cacaaaaatc
     2281 ggtatcatta gtccaattca tcgggaaaga tggagagaat tttgatatcc agtgttctcc
     2341 cagtggtttt gaccgggaag gagagttgat gttgtcattg ttttacaata aaacagttat
     2401 tgcccggtta acattttcag tcattctgac tcaaaatgga cacattgctt ttattggcgg
     2461 attacaggga gcccctaaaa ataccggacc tgatgttatt cggtgcgcaa cccgggcctg
     2521 ttatgggatt ttcccaaaac ggattatttt tgaagcattt tgtgcgttga tgaaagcttg
     2581 caatatctct gagtgtctgg cagtcagtga gcacagtcat gttttccggc aattgagata
     2641 ctggtatcag aaacgcaaaa cctttgttgc ggtctatagt gatttctggg agtctgtagc
     2701 aggaaaaacc tgtggtgact ggtacagatt accaacccag gtgattcgaa agccgctaag
     2761 cgatatagcc agtaaaaaac gctctgagta ccgaaaacga tacgctttgc tggattatat
     2821 ccatgaaact actatcagct ctttggatgc atatcctgta cactcagaac atcagaattt
     2881 aaattaaggt ttgatgtatt ctctgaataa aacagtaatg ataattttgg tagaggcatt
     2941 cgcactaaat aatgaaaaaa tataaatctg agtttattcc tgaatttaag aaaaattacc
     3001 tttcccctgt ttactggtct acatggttcc ttttgggaat gattgcaggt atttcaatgt
     3061 ttcccccttc attcagagat cctgtcttgg caaaaatagg gcgttgggcg ggcagattga
     3121 gcaaaaaagc tcgtcgcagg gcgacgatta atttatcgct ttgtttccca gaaaagagtg
     3181 atacagaacg ggaaataatt gtcgacaaaa tgtttatcac agcattgcaa tccatagtga
     3241 tgatggcaga actggcaatt cgtggtccgg aaaagttcca gaaacgagtg ttctggaaag
     3301 gcctcgaaat tcttgaggaa attcgacaca ataatagaaa tgtgattttt ctggttcccc
     3361 atggctggag cgtggatatt cctgcaatgt tgctggcagc tcagggaaaa aaaatggccg
     3421 ccatgtttca tcagcaacga aatccagtga ttgattatgt ctggaattca gtacggcgta
     3481 aattcggggg gcgcttacat gcccgggagg atgggataaa accatttatt cagtcagtac
     3541 gccagggata ctggggatat tacctcccag atcaggatca tggtcctgaa tacagtgaat
     3601 ttgctgattt ttttgcgacc tataaagcga cattaccaat cattggacgt ctgatgaaca
     3661 tcagtcaggc tatgattata ccacttttcc cggtttatga tgaaaaaaaa catctactga
     3721 ctattgaaat tcggccacc
//
LOCUS       DACAOP010000202         3596 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.203, whole genome shotgun sequence.
ACCESSION   DACAOP010000202 DACAOP010000000
VERSION     DACAOP010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3596
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.203"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..209)
                     /locus_tag="IT892_004485"
     CDS             complement(<1..209)
                     /locus_tag="IT892_004485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase family
                     protein"
                     /protein_id="HAP3137597.1"
                     /translation="MFLASLLRRIAFSYYDYKAYNFNIEKTEFVVIHIPDQIGDAMAI
                     FPVIRALELHKIKHLLIVTSIINLEV"
     gene            524..1840
                     /gene="shiA"
                     /locus_tag="IT892_004486"
     CDS             524..1840
                     /gene="shiA"
                     /locus_tag="IT892_004486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate transporter"
                     /protein_id="HAP3137598.1"
                     /translation="MDSTLISTRPDEGTLSLSRARRAALGSFAGAVVDWYDFLLYGIT
                     AALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLGGVIFGHFGDRLGRKRMLMLTVW
                     IMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPENKKA
                     FYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNG
                     MEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIALRLCELLTMYIVTAFALNY
                     STQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYITGALIGTLSAFPFF
                     MALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVG
                     GGFTPFIAAALITYFAGNWHSVAIYLLAGCLISAMTALLMKDNQRS"
     gene            1942..3396
                     /gene="amn"
                     /locus_tag="IT892_004487"
     CDS             1942..3396
                     /gene="amn"
                     /locus_tag="IT892_004487"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HAP3137599.1"
                     /translation="MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGKYITSGELPDE
                     NARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLT
                     LLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETAD
                     GIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGC
                     SQILDPDSPYIALSCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITADGQGITLV
                     NIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAV
                     LPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASAL
                     RFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAIS
                     EHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR"
BASE COUNT          870 a          861 c          837 g         1028 t
ORIGIN      
        1 acttctaaat taattatcga cgtaacaatt agtagatgct taattttatg caattcaagc
       61 gcccgaataa ctggaaagat ggccatagca tcgccaatct gatcgggaat atggataaca
      121 acaaactctg ttttttcaat attgaaatta taagctttat aatcgtagta actaaatgca
      181 atacgtctca acaatgatgc taaaaacata cctaacctcg cctccctact ggttataatg
      241 caaagcagtc tatcagactc atcagggtgc cattttgtgc atatgcggac ttttatgttt
      301 catatctcga acctgtgggt cctctgctta atccttaaac aacaccagca actcccgcgc
      361 tttcatcttc cagcgaattt ttcatgttgc cgctaatcag ccataaaatc atttgcagat
      421 gcgctctgtc gaggtagtct cataaggttc gtttatagat cgacggcaat gtgagttacc
      481 ttttccatac taattataaa aagacagtac aaacaggatc attatggact ccacgctcat
      541 ctccacccgt cccgatgaag ggacgctttc gttaagtcgc gcccgacgag ctgcgttagg
      601 cagtttcgct ggtgccgtcg tcgactggta tgatttttta ctctatggca ttaccgccgc
      661 actggtgttt aatcgcgagt ttttcccgca agtaagcccg gcgatgggaa cgctcgccgc
      721 atttgctacc tttggcgtcg gattcctttt ccgtccgctc ggcggtgtca ttttcggtca
      781 ctttggcgac cggctgggac gtaagcgcat gttaatgctg accgtctgga tcatgggcat
      841 cgcgacagcc ttgattggta ttcttccttc attctcgacc attgggtggt gggcacctat
      901 tttgctggtg acactgcgtg ccattcaggg atttgccgtc ggcggcgaat ggggaggcgc
      961 ggcgttgctt tccgttgaaa gtgcgccgga aaataaaaaa gccttttaca gtagcggtgt
     1021 acaagttggc tacggagtag gtttactgct ttcaaccgga ctggtttcat tgatcagtat
     1081 gatgacaact gacgaacagt ttttaagctg gggctggcgc attcctttcc tgtttagcat
     1141 cgtactggta ctgggagcat tgtgggtgcg caatggcatg gaagagtccg cggaatttga
     1201 acaacagcaa cattatcaag ctgccgcgaa aaaacgcatc ccggttatcg aagctctgtt
     1261 acgacatccc ggtgctttcc tgaagattat tgcgctacga ctgtgcgaat tgctgacgat
     1321 gtacatcgtt actgcctttg cacttaatta ttcaacccag aatatggggc taccgcgcga
     1381 acttttcctt aatattggtt tgctggtagg tggattaagc tgcctgacaa ttccctgttt
     1441 tgcctggctt gccgatcgtt ttggtcgccg cagggtttat atcacaggcg cgttaatcgg
     1501 aacgttgagc gcatttcctt tctttatggc gcttgaagca caatctattt tctggatagt
     1561 tttcttctcc ataatgctgg caaacattgc gcatgacatg gtggtgtgtg tgcaacaacc
     1621 gatgtttacc gaaatgtttg gtgccagtta tcgctatagt ggtgctggag tcggttatca
     1681 ggttgccagt gtggttggcg gtggatttac accttttatt gccgctgcgc tcatcactta
     1741 ctttgccggg aactggcata gcgtcgccat ttatttgctg gctggatgtc tgatttccgc
     1801 aatgaccgct ttattgatga aagacaatca acgctcgtga tagcctggcg aagatcatcc
     1861 gatcttcgcc ttatactttt gtttcacatt cctgtgacat actatcagat gtgcggtaat
     1921 tgtatggaac aggagacaca catgaataat aagggctccg gtctgacccc agctcaggca
     1981 ctggataaac tcgacgcgct gtatgagcaa tctgtagttg ctttacgcaa cgccattggc
     2041 aaatatatta caagtggcga attacctgat gaaaacgccc gcaaacaagg tctttttgtc
     2101 tatccatcac tgaccgtaac ctgggacggt agcacaacta atccccccaa aacgcgcgca
     2161 tttggtcgtt ttactcacgc aggcagctac accaccacga ttactcgccc tactctcttt
     2221 cgttcgtatc tcaatgaaca acttacgttg ctgtatcagg attatggtgc gcatatctct
     2281 gtgcaaccct cgcagcatga aataccttat ccttatgtca tcgatggctc tgaattgaca
     2341 cttgatcgct caatgagcgc tggtttaact cgctacttcc cgacaacaga actggcgcaa
     2401 atcggcgatg aaactgcaga cggcatttat catccaacgg aattctcccc gttatcgcat
     2461 tttgatgctc gccgggttga tttttccctc gcacggttgc gccattatac cggtacgcca
     2521 gtagaacatt ttcaaccgtt cgtcttgttt accaactaca cacgttatgt ggatgaattc
     2581 gttcgttggg gatgcagcca gatcctcgat cctgatagtc cctacattgc cctttcttgt
     2641 gctggcggga actggatcac tgccgaaacc gaagcgccag aagaagccat ttccgacctt
     2701 gcatggaaaa aacaccagat gccagcatgg catttaatta ccgctgatgg tcagggtatt
     2761 actctggtga atattggcgt gggaccgtcc aatgctaaaa ccatctgcga tcatctggca
     2821 gtgctacgcc cggatgtctg gttgatgatt ggtcactgtg gcggattacg tgaaagccag
     2881 gccattggag attatgtcct tgcacacgct tatttacgcg atgaccacgt tcttgatgcg
     2941 gttctgccgc ccgatattcc tattccgagc attgctgaag tgcaacgtgc gctttatgac
     3001 gctaccaagt tagtcagcgg caggcctggt gaggaagtca aacagcggct gcgtacaggt
     3061 actgtggtaa ccacagatga caggaactgg gagttacgtt actcagcttc tgcacttcgt
     3121 tttaacttaa gccgggccgt agcaattgat atggaaagtg caaccattgc cgcgcaagga
     3181 tatcgtttcc gcgtgccata cgggacacta ctgtgtgttt cagataaacc gttacatggt
     3241 gagattaagc ttcccggcca ggctaaccgt ttttatgaag gcgctatttc cgaacacctg
     3301 caaattggca ttcgggcgat cgatttgctg cgcgcagaag gcgaccgact gcattcacgt
     3361 aaattacgaa cctttaatga gccgccgttc cgataataag ttatgaacct tcttatcaga
     3421 aatagatgtg aaggattaag taagacatct ggcaaatagc ctgcaataaa cgcgggctgt
     3481 ttgcttcctt gggcagatgc gagttttatt atcatcttaa tgatttccac atattaaaag
     3541 caagtatgct ttcaaaacac aattataaaa aatcccgcca acaacattag ttttta
//
LOCUS       DACAOP010000203         3592 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.204, whole genome shotgun sequence.
ACCESSION   DACAOP010000203 DACAOP010000000
VERSION     DACAOP010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3592
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.204"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            91..327
                     /locus_tag="IT892_004488"
     CDS             91..327
                     /locus_tag="IT892_004488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YcgZ"
                     /protein_id="HAP3137600.1"
                     /translation="MHQNSVTLDSAGAITRYFAKANLHTQQETLGEIVTEILKDGRNL
                     SRKSLCAKLLCRLEHATGEEEQKHYNALIGLLFE"
     gene            370..642
                     /locus_tag="IT892_004489"
     CDS             370..642
                     /locus_tag="IT892_004489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YmgA"
                     /protein_id="HAP3137601.1"
                     /translation="MKTSDNERIKYEITGQAVLQILRMKINFSLQTLIKQLLVMKSAE
                     EDAFRRDLIDSIIRDFSNSDSGGPNRRTATADNKSMFNGKKINRIH"
     gene            671..937
                     /gene="ariR"
                     /locus_tag="IT892_004490"
     CDS             671..937
                     /gene="ariR"
                     /locus_tag="IT892_004490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm/acid-resistance regulator AriR"
                     /protein_id="HAP3137602.1"
                     /translation="MLEDTTIHNAITDKALASYFRSSGNLLEEESAVLGQAVTNLMLS
                     GDNVNNKNIILSLIHSLETTSDILKADVIRKTLEIVLRYTADDM"
     gene            1050..1298
                     /locus_tag="IT892_004491"
     CDS             1050..1298
                     /locus_tag="IT892_004491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137603.1"
                     /translation="MNNSIPERFIFQCALFKNLEREVFMTHGYVDSHIIDQALRLRLK
                     DETSVILSDLYLQILQYIEMHKTTLTDIIINDRESVLS"
     gene            1630..3153
                     /locus_tag="IT892_004492"
     CDS             1630..3153
                     /locus_tag="IT892_004492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415686.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HAP3137604.1"
                     /translation="MRNTLIPILVAICLFITGVAILNIQLWYSAKAEYLAGARYAANN
                     INHILEEASQATQTAVNIAGKECNLEEQYQLGTEAALKPHLRTIIILKQGIVWCTSLP
                     GNRVLLSRIPVFPDSNLLLAPAIDTVNRLPILLYQNQFADTRILVTISDQHIRGALNV
                     PLKGVRYVLRVADDIIGPTGDVMTLNGHYPYTEKVHSTKYHFTIIFNPPPLFSFYRLI
                     DKGFGILIFILLIACAAAFLLDRYFNKSATPEEILRRAINNGEIVPFYQPVVNGREGT
                     LRGVEVLARWKQPHGGYISPAAFIPLAEKSGLIVPLTQSLMNQVARQMNAIASKLPEG
                     FHIGINFSASHIISPTFVDECLNFRDSFTRRDLNLVLEVTEREPLNVDESLVQRLNIL
                     HENGFVIALDDFGTGYSGLSYLHDLHIDYIKIDHSFVGRVNADPESTRILDCVLDLAR
                     KLSISIVAEGVETKEQLDYLNQNNITFQQGYYFYKPVTYIDLVKIILSKPKVKVVVE"
     gene            3285..3503
                     /locus_tag="IT892_004493"
     CDS             3285..3503
                     /locus_tag="IT892_004493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137605.1"
                     /translation="MNNSNNLDYFTLYIIFSIAFMLITLLVILIAKPSTGLGEVLVTI
                     NLLNALVWLAINLVNRLRERLVNHRDQQ"
BASE COUNT         1043 a          697 c          760 g         1092 t
ORIGIN      
        1 attaatttat cattctgtac acatatttcg tacaagtttg ctattgttac ttcacttaac
       61 attgattaac atttttaaca gaggcgtagc atgcatcaaa attcagtgac tttagattct
      121 gcgggagcaa tcactcgtta ctttgcaaaa gctaacttgc atactcagca ggaaactctc
      181 ggggaaattg tgactgagat tttgaaagat ggacgtaatc tgagtcgaaa gtcgctttgt
      241 gccaaacttc tttgccgact ggaacacgcg acgggggaag aggaacagaa acattataat
      301 gcactaattg ggttgctttt tgaataatgc aacagcctga ttatttaaca ggttagctat
      361 gaagtcgtta tgaagacatc tgataatgaa cgtataaaat atgaaattac tggccaggcg
      421 gtgctccaga tactgcgcat gaagataaat ttttcattgc agactcttat taagcaatta
      481 ctcgtaatga aatcggctga ggaagatgct ttccgacgcg atttaattga cagcataatt
      541 cgtgatttta gcaatagtga ttcaggaggg ccaaaccgaa gaacagcgac agctgacaat
      601 aaaagtatgt tcaatggtaa gaaaataaac agaatacatt aaaatttcat aagtaagatg
      661 agaggttacc atgcttgaag atactacaat tcataatgca ataactgata aagcgttagc
      721 aagttacttt cgcagttcgg gtaatttgtt agaagaagaa tcagcagtgt tagggcaggc
      781 tgtcaccaat ttaatgcttt caggcgataa tgttaataat aaaaatatta tcttaagtct
      841 gatacactcc ttggaaacaa caagtgatat tctcaaagct gatgtgatta gaaaaacact
      901 ggaaatcgtg ttgcgataca cagctgatga tatgtaactt ctaattatta agtataagtt
      961 tatagaaaac tcattcatct tatttttgtc tgtcgcttta gactatacac agcataattt
     1021 tattgggtta atatttctac gaggctgaca tgaataattc aatcccagag agatttattt
     1081 ttcaatgtgc tttgtttaaa aatctcgaga gggaggtgtt catgacgcat gggtatgttg
     1141 atagtcatat tattgatcag gctttacgct tgcgtttaaa agatgaaacc agtgtgattc
     1201 tttctgatct ctatctgcaa atattgcagt acattgaaat gcataagact acactaacgg
     1261 atatcattat taatgacagg gaatccgtgc tctcttagaa cttgagtaag gttttagaat
     1321 aaacatcagc tgtatcacca tgctgatgca aagtgagcat ttcaggcgtt atgctttctt
     1381 attatgtccg caatatcagg tgtcaagaat ggagagttct cgctctccat tcttgacgcc
     1441 tgatatcccg cctaacttat tttgtactgc ctacattatg ctcaataatt aatgggttag
     1501 atcaagatgg agaaaatttt atcttcggcg tggatatttc ttatgctctc taccatgctc
     1561 tctgtagatg ccagcgcgag cgaatgaatg gcattttcat gtattaaacc ctttggccgg
     1621 gacaagcaaa tgcgcaatac actcataccc atcctcgttg cgatatgctt gtttattacc
     1681 ggtgtcgcta ttttgaacat ccagctctgg tattccgcaa aagcagagta cctggcggga
     1741 gcgagatatg ccgccaacaa tatcaatcat atacttgaag aagcgtcaca agcgactcaa
     1801 acagcggtta acattgccgg gaaggaatgc aacctcgagg agcaatatca gcttggcact
     1861 gaagcagctc tgaaacctca cctgcgcaca atcatcattc tcaaacaggg aatagtctgg
     1921 tgtacatccc tgcctgggaa tcgggtcctg ttgtctcgta ttcctgtttt cccggacagt
     1981 aatttactgt tggctccagc aatcgacacc gttaatagat tacctatcct gctctatcag
     2041 aaccaatttg cagatacgcg cattttggtt acgataagcg atcagcatat tcgtggggca
     2101 cttaatgtac ccttgaaagg ggtaaggtat gtattacgcg tggcggatga cattattgga
     2161 ccaacgggtg atgtgatgac gcttaatgga cattatccct ataccgagaa ggttcactcc
     2221 acaaaatatc atttcactat tatctttaac ccgccgccac tctttagctt ctacagactt
     2281 atcgataaag gctttgggat tttaatattt attctgttaa tcgcctgcgc cgctgccttc
     2341 ctgcttgata gatatttcaa taaaagcgca acgcctgaag agatcctgcg acgggcaata
     2401 aataatgggg agatcgtccc tttttaccaa cctgtggtaa atggtcggga agggacattg
     2461 cggggagttg aggtgttagc ccgctggaaa caacctcacg gtggatatat atcacccgcg
     2521 gcatttattc cacttgctga aaaatccgga ttaatcgttc cgcttacgca aagcctgatg
     2581 aatcaggttg ccagacagat gaacgctatc gcgagtaaat tgccggaagg ttttcatatt
     2641 ggaattaatt ttagcgcttc gcatattatt tcgccgacgt ttgtcgacga gtgtttaaat
     2701 ttccgtgaca gttttacccg ccgcgattta aaccttgttc tggaagtcac cgagcgtgag
     2761 ccattgaatg ttgatgaaag tctggttcag cggttgaaca tactgcatga aaatggtttt
     2821 gtcatcgcac tggatgattt cggtactggc tactcagggc tttcttatct tcatgacctg
     2881 catattgatt atatcaaaat tgatcacagt ttcgttggcc gcgtaaacgc agacccagaa
     2941 tcaacccgaa ttctggattg tgtattggat ctggcgcgta aactttcgat cagtatcgtc
     3001 gctgaaggtg tcgaaacgaa agaacaactt gactatctga accaaaataa tatcacattt
     3061 cagcagggtt attatttcta taaacctgtt acatacatcg acctggtcaa aattatcctt
     3121 tctaaaccga aggtgaaggt tgtggttgag tgaaaattga tcagtaaggc catagtgcgg
     3181 tgtaattata gacagctaat tagctcgttg cctcttgtta ctattgttca ttattttgtt
     3241 tgctataatt gtttgaaagt tttgacagga ttgccattag tagcatgaac aatagtaata
     3301 atctggatta tttcactctc tatatcatat tttccattgc atttatgctg atcaccctcc
     3361 tggtcatcct tattgcaaaa cccagtaccg ggctgggaga agtgcttgtg acgataaatt
     3421 tgcttaatgc ccttgtttgg ctggcgatca atctggttaa tcgattaaga gaaagactcg
     3481 tcaaccacag ggatcagcaa taatctttca gtttctcact gtcagtatgc ggctgaatgg
     3541 gttgctggca gtgaacgcct ggatcattga aggaaaggca ttattgcgca aa
//
LOCUS       DACAOP010000204         3579 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.205, whole genome shotgun sequence.
ACCESSION   DACAOP010000204 DACAOP010000000
VERSION     DACAOP010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3579
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.205"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            28..243
                     /locus_tag="IT892_004494"
     CDS             28..243
                     /locus_tag="IT892_004494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001384468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAP3137606.1"
                     /translation="MSIERFQSLATEGKMLSLSWWENEYAVLQWKNHVLHAKAQQEGR
                     ESIFDFYKISIAHITREYSFKKDKDNV"
     gene            236..622
                     /locus_tag="IT892_004495"
     CDS             236..622
                     /locus_tag="IT892_004495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HAP3137607.1"
                     /translation="MFDVHVVLDNQIGQLALLGKTLGNKGIGLEGGGIFTVGDECHAH
                     FLVEQGKEAKIALEQAGLLVLAIRTPLIRKLKQEKPGELGEIARVLAENNINILVQYS
                     DHANQLILITDNDSMAASVTLPWAIK"
     gene            630..1316
                     /locus_tag="IT892_004496"
     CDS             630..1316
                     /locus_tag="IT892_004496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP3137608.1"
                     /translation="MANLIRKEVTFESSIAAIGAAMSDISRVKILSALMDGRAWTATE
                     LSSVANISASTASSHLSKLLDCQLITVVAQGKHRYFRLAGKDIAELMESMMGISLNHG
                     VHAKVSTPVHLRKARTCYDHLAGEVAVKIYDSLCQQQWITENGSMITLSGIQYFHEMG
                     IDVPSKHSRKICCACLDWSERRFHLGGYVGAALFSLYESKGWLTRHLGYREVTITEKG
                     YAAFKTHFHI"
     gene            complement(1294..1917)
                     /gene="tetR(B)"
                     /locus_tag="IT892_004497"
     CDS             complement(1294..1917)
                     /gene="tetR(B)"
                     /locus_tag="IT892_004497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HAP3137609.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            1999..3204
                     /gene="tet(B)"
                     /locus_tag="IT892_004498"
     CDS             1999..3204
                     /gene="tet(B)"
                     /locus_tag="IT892_004498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HAP3137610.1"
                     /translation="MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
     gene            complement(3317..>3579)
                     /locus_tag="IT892_004499"
     CDS             complement(3317..>3579)
                     /locus_tag="IT892_004499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP3137611.1"
                     /translation="EVMPIIGWNELEKISLEYITGKVNAIVSKLIQENQLKAYDDDVL
                     KNLLNGWFMHIAIHAKNLKELADKKGQFIAIYRGFLLSLKDK"
BASE COUNT          982 a          663 c          778 g         1156 t
ORIGIN      
        1 ccactattaa gtcatgtagc tggttttatt tcaattgaac gttttcaaag tctagctaca
       61 gaaggaaaaa tgttatcgct atcttggtgg gaaaacgaat acgcagttct gcaatggaaa
      121 aatcatgttt tacatgcgaa agctcaacaa gaagggcgag agtcaatatt tgatttttac
      181 aaaattagta ttgctcatat tactcgcgaa tattcattta aaaaggacaa ggataatgtt
      241 tgatgttcac gttgttttag ataatcaaat aggacaatta gcattactag gaaaaacatt
      301 aggtaataaa ggtattggat tggaaggggg agggatattt acggttggtg atgaatgcca
      361 tgctcatttt cttgttgaac aaggaaagga agctaaaata gcgctagagc aagctggact
      421 gttagtactt gcgatccgga caccattaat tcgtaagtta aaacaggaaa aaccggggga
      481 acttggcgaa atagcacgag tattggcgga gaataacatt aatattttag tgcaatacag
      541 tgaccatgct aaccaactga tattaataac ggacaatgat agtatggctg catctgttac
      601 gctcccttgg gcaataaagt gaacttgcga tggctaattt aatacgaaaa gaggttacct
      661 ttgagtcctc aatagccgcg ataggggcgg ctatgtctga catttcacga gttaaaatac
      721 tcagtgcttt gatggatggg cgagcttgga cggccactga gctaagttct gtggcgaata
      781 tatcagcttc aacggcgagc agtcatttat ctaaattatt agattgccag ctaatcacag
      841 tagtagctca aggcaagcat cgttattttc ggctagcagg aaaagatatt gctgaattga
      901 tggaaagtat gatggggatc tccttaaacc atggcgtaca tgccaaagtt tccacgccag
      961 tgcatttacg aaaagcacgt acttgctatg atcatttagc tggcgaagtt gccgttaaga
     1021 tctatgattc cctttgtcaa cagcaatgga tcactgaaaa tggttcaatg atcacattaa
     1081 gtggtattca atattttcat gaaatgggaa ttgacgttcc ttccaaacat tcacgtaaaa
     1141 tctgttgtgc gtgtttagat tggagtgaac gccgtttcca tttaggtggg tacgttggag
     1201 ccgcattatt ttcgctttat gaatctaaag ggtggttaac tcgacatctt ggttaccgtg
     1261 aagttaccat cacggaaaaa ggttatgctg cttttaagac ccactttcac atttaagttg
     1321 tttttctaat ccgcatatga tcaattcaag gccgaataag aaggctggct ctgcaccttg
     1381 gtgatcaaat aattcgatag cttgtcgtaa taatggcggc atactatcag tagtaggtgt
     1441 ttccctttct tctttagcga cttgatgctc ttgatcttcc aatacgcaac ctaaagtaaa
     1501 atgccccaca gcgctgagtg catataatgc attctctagt gaaaaacctt gttggcataa
     1561 aaaggctaat tgattttcga gagtttcata ctgtttttct gtaggccgtg tacctaaatg
     1621 tacttttgct ccatcgcgat gacttagtaa agcacatcta aaacttttag cgttattacg
     1681 taaaaaatct tgccagcttt ccccttctaa agggcaaaag tgagtatggt gcctatctaa
     1741 catctcaatg gctaaggcgt cgagcaaagc ccgcttattt tttacatgcc aatacaatgt
     1801 aggctgctct acacctagct tctgggcgag tttacgggtt gttaaacctt cgattccgac
     1861 ctcattaagc agctctaatg cgctgttaat cactttactt ttatctaatc tagacatcat
     1921 taattcctaa tttttgttga cactctatca ttgatagagt tattttacca ctccctatca
     1981 gtgatagaga aaagtgaaat gaatagttcg acaaagatcg cattggtaat tacgttactc
     2041 gatgccatgg ggattggcct tatcatgcca gtcttgccaa cgttattacg tgaatttatt
     2101 gcttcggaag atatcgctaa ccactttggc gtattgcttg cactttatgc gttaatgcag
     2161 gttatctttg ctccttggct tggaaaaatg tctgaccgat ttggtcggcg cccagtgctg
     2221 ttgttgtcat taataggcgc atcgctggat tacttattgc tggctttttc aagtgcgctt
     2281 tggatgctgt atttaggccg tttgctttca gggatcacag gagctactgg ggctgtcgcg
     2341 gcatcggtca ttgccgatac cacctcagct tctcaacgcg tgaagtggtt cggttggtta
     2401 ggggcaagtt ttgggcttgg tttaatagcg gggcctatta ttggtggttt tgcaggagag
     2461 atttcaccgc atagtccctt ttttatcgct gcgttgctaa atattgtcgc tttccttgtg
     2521 gttatgtttt ggttccgtga aaccaaaaat acacgtgata atacagatac cgaagtaggg
     2581 gttgagacgc aatcgaattc ggtatacatc actttattta aaacgatgcc cattttgttg
     2641 attatttatt tttcagcgca attgataggc caaattcccg caacggtgtg ggtgctattt
     2701 accgaaaatc gttttggatg gaatagcatg atggttggct tttcattagc gggtcttggt
     2761 cttttacact cagtattcca agcctttgtg gcaggaagaa tagccactaa atggggcgaa
     2821 aaaacggcag tactgctcgg atttattgca gatagtagtg catttgcctt tttagcgttt
     2881 atatctgaag gttggttagt tttccctgtt ttaattttat tggctggtgg tgggatcgct
     2941 ttacctgcat tacagggagt gatgtctatc caaacaaaga gtcatcagca aggtgcttta
     3001 cagggattat tggtgagcct taccaatgca accggtgtta ttggcccatt actgtttgct
     3061 gttatttata atcattcact accaatttgg gatggctgga tttggattat tggtttagcg
     3121 ttttactgta ttattatcct gctatcgatg accttcatgt taacccctca agctcagggg
     3181 agtaaacagg agacaagtgc ttagttattt cgtcaccaaa tgatgttatt ccgcgaaata
     3241 taatgaccct cttgataacc caagagggca ttttttacga taaagaagat ttagcttcaa
     3301 ataaaaccta tctattttat ttatctttca agctcaataa aaagccgcgg taaatagcaa
     3361 taaattggcc ttttttatcg gcaagctctt ttaggttttt cgcatgtatt gcgatatgca
     3421 taaaccagcc attgagtaag tttttaagca catcatcatc ataagcttta agttggttct
     3481 cttggatcaa tttgctgaca atggcgttta ccttaccagt aatgtattca aggctaattt
     3541 tttcaagttc attccaacca atgataggca tcacttctt
//
LOCUS       DACAOP010000205         3560 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.206, whole genome shotgun sequence.
ACCESSION   DACAOP010000205 DACAOP010000000
VERSION     DACAOP010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3560
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.206"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            81..914
                     /gene="xapA"
                     /locus_tag="IT892_004500"
     CDS             81..914
                     /gene="xapA"
                     /locus_tag="IT892_004500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine phosphorylase"
                     /protein_id="HAP3137612.1"
                     /translation="MYQAQFSHNPLYCVDIIKTYKPDFTPRVAFILGSGLGALADQIE
                     NAVAISYEKLPGFPVSTVHGHAGELVLGYLQGVPVVCMKGRGHFYEGRGMTIMTDAIR
                     TFKLLGCELLFSTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDERFGERFFSL
                     ANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV
                     PEVISARHCELKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI
                     A"
     gene            974..2230
                     /gene="xapB"
                     /locus_tag="IT892_004501"
     CDS             974..2230
                     /gene="xapB"
                     /locus_tag="IT892_004501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine/proton symporter XapB"
                     /protein_id="HAP3137613.1"
                     /translation="MSIALRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVY
                     SSKGIAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGVLFYAASVTDPDMMFWVMLVN
                     AMAFMPTIALSNSVSYSCLAQAGLDPVTAFPPIRVFGTVGFIVAMWAVSLLHLELSSL
                     QLYIASGASLLLSAYALTLPKIPVAEKKATTSLASKLGLDAFVLFKNPRMAIFFLFAM
                     MLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLK
                     RFGIKTVMLMSMVAWTLRFGFFAYGDPSTTGFILLLLSMIVYGCAFDFFNISGSVFVE
                     QEVDSSIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFSVDGVKDWHTIWLMFAGYAL
                     FLAVIFFFGFKYNHDSEKITHRSVTH"
     gene            2283..2441
                     /locus_tag="IT892_004502"
     CDS             2283..2441
                     /locus_tag="IT892_004502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1427 family protein"
                     /protein_id="HAP3137614.1"
                     /translation="MKDILFSSGVGFGIGALFTIVRLPIPVPNVLPGILSIVFMYVGY
                     LVVKYFMP"
     gene            2482..3366
                     /gene="xapR"
                     /locus_tag="IT892_004503"
     CDS             2482..3366
                     /gene="xapR"
                     /locus_tag="IT892_004503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XapR"
                     /protein_id="HAP3137615.1"
                     /translation="MERVYRTDLKLLRYFLAVAEELHFGRAAARLNMSQPPLSIHIKE
                     LENQLGTQLFIRHSRSVVLTHAGKILMEESRRLLVNANNVLARVEQIGRGEAGRIELG
                     VVGTAMWGRMRPVMRRFLRENPNVDVLFREKMPAMQMALLERRELDAGIWRMATEPPA
                     GFTSLRLHESAFLVAMPEEHHLSSFSTVPLEALRDEYFVTMPPVYTDWDFLQRVCQQV
                     GFSPVVIREVNEPQTVLAMVSMGIGITLIADSYAQMNWPGVIFRPLKERIPADLYIVY
                     ETQQVTPALVKLLAALAQ"
     gene            complement(3477..>3560)
                     /locus_tag="IT892_004504"
     ncRNA           complement(3477..>3560)
                     /ncRNA_class="other"
                     /locus_tag="IT892_004504"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
BASE COUNT          784 a          775 c          971 g         1030 t
ORIGIN      
        1 gaaaaaagtg tattggtatg agttagggca atctcgttat aaaaaggcgt tagattccac
       61 cctacaaaaa aaggatatat atgtatcagg ctcagttttc tcataaccca ctgtattgcg
      121 tagatattat caagacttat aaacctgatt tcacgccacg agtggccttt attttaggtt
      181 ccgggctggg cgcgctggcc gatcagattg agaacgcggt cgcaatttcc tacgaaaagc
      241 tgcctgggtt cccggtaagt accgtacatg gccatgcggg tgagctggtg ctgggttatc
      301 tccagggggt gccagtggtg tgcatgaaag gtcgcggaca tttctacgaa ggtcgtggga
      361 tgaccatcat gacggatgca atccgtacct ttaagttgct gggctgcgag ttgctgttca
      421 gcaccaatgc ggctggctca ctgcgtcctg aagtgggggc cggcagtctg gtcgcattga
      481 aagatcacat caacaccatg ccgggaacgc cgatggtggg tcttaatgat gaacgttttg
      541 gtgagcgctt cttctcgctg gcgaatgcct acgatgcgga ataccgcgca ctgttacaaa
      601 aagtggcgaa agaagagggg ttccctctga cggagggcgt gttcgtctcg tatccgggtc
      661 cgaatttcga gactgcggcg gaaattcgca tgatgcaaat tattggtggg gatgttgttg
      721 gtatgtctgt ggtgcctgag gttatttctg ctcgccattg cgaacttaaa gtcgttgcgg
      781 tctctgcgat taccaacatg gcggaaggtt taagcgatgt gaaattgtca catgcgcaaa
      841 cgctggcggc tgcggagctc tctaagcaga acttcatcaa ccttatttgt ggctttctgc
      901 gcaaaattgc ctgagaaaaa caataagaaa cggcctcgcg ggtgaggcca aatgatgcga
      961 caaggaaacg attatgagca tcgctttgcg cttaaaggta atgtcctttt tgcaatattt
     1021 tatctggggg agctggctgg ttaccctcgg ttcttacatg attaataccc ttcatttcac
     1081 cggcgctaat gttggcatgg tttacagttc caaagggatc gccgcgatta ttatgcctgg
     1141 tataatgggg atcatcgcag acaaatggct gcgtgcagaa cgtgcataca tgctgtgtca
     1201 cctggtgtgt gcgggcgtac ttttttatgc ggcatccgta actgatccgg atatgatgtt
     1261 ttgggtgatg ttagtcaatg cgatggcgtt tatgccgact attgcgttat cgaacagcgt
     1321 ctcttattcc tgtcttgccc aggcagggct tgacccggtg accgctttcc cgcccattcg
     1381 cgtttttggt acggtggggt tcattgtcgc catgtgggca gtaagcctgc tgcatctgga
     1441 attgagtagt ctgcagctgt atatcgcgtc cggtgcgtca ttgctgctgt cggcttatgc
     1501 gctgactttg ccgaagattc cggttgcgga gaaaaaagcg actacatcgc ttgccagcaa
     1561 gctgggtctg gatgccttcg tgctgtttaa aaatccacgc atggctatct ttttcctctt
     1621 cgccatgatg ctgggcgcgg tgctgcaaat taccaacgtt tttggcaacc cgttcctgca
     1681 tgatttcgcc cgtaatcctg agtttgctga cagttttgtg gtgaaatatc cctccatttt
     1741 actgtcagtt tcacagatgg cagaagtggg ctttatactg actatcccat tctttttaaa
     1801 gcgatttggc attaaaaccg tcatgctgat gagtatggtg gcctggacgc tgcgctttgg
     1861 cttcttcgcc tatggcgatc cgtcaacaac cggatttatt ttgctgctgc tgtcgatgat
     1921 tgtttatggc tgtgcattcg atttcttcaa tatttctggt tcggtatttg tcgaacagga
     1981 agttgattcc agcattcgtg ccagcgcgca gggccttttt atgacgatgg taaatggcgt
     2041 cggcgcatgg gttggctcga ttctgagcgg tatggcagtg gattacttct cggtggatgg
     2101 cgtaaaagac tggcatacca tttggctgat gtttgcaggg tatgctcttt tcctcgcagt
     2161 gatatttttc tttgggttta aatataacca tgactctgaa aagataacgc atcgttcagt
     2221 tacacattaa aaggattcgc agctctgttc cttggggctg cttttatgat aaaggttaat
     2281 tagtgaaaga tattttattt tcttctggcg ttggttttgg cattggtgct ttgtttacaa
     2341 tcgtgcgatt acctattcct gttccaaatg tattgccggg tatattatcc atcgtgttta
     2401 tgtatgtcgg atatctggtg gtgaaatact ttatgccatg ataatttaat acgatgtatt
     2461 tattatatgg agcacttaat tatggaacgc gtatatagaa cagatcttaa gttgctccgt
     2521 tattttcttg ccgtagcgga agagttgcat tttggtcgcg cagcagcgcg tttaaatatg
     2581 tctcagcctc cgctcagtat tcatattaaa gagctggaaa atcaactcgg cacgcagctt
     2641 tttattcgcc attcgcgcag cgtcgtactg acacacgcgg gcaaaatctt gatggaagaa
     2701 tcgcgtcgat tgctggtgaa tgcaaataat gtattggctc gggttgaaca aataggtcgg
     2761 ggagaagcag ggcggattga actcggggtt gtgggaacgg caatgtgggg acggatgcgt
     2821 ccggttatgc ggcgattcct cagggaaaat cctaacgttg acgttctttt tcgcgaaaag
     2881 atgcccgcga tgcaaatggc cctgctggaa cgacgtgaac tcgatgccgg aatctggaga
     2941 atggcgacag aaccaccggc aggttttacc agcttacggt tgcatgaatc ggcgtttctg
     3001 gtggcgatgc ctgaagagca tcatctctca tcattttcca ccgttccgct ggaagcgcta
     3061 cgtgacgagt attttgttac aatgccgccc gtgtacactg actgggattt tttgcagcga
     3121 gtttgccagc aggtgggatt ttcaccggtt gttattcgcg aagttaatga accgcaaacg
     3181 gtactcgcca tggtcagtat gggtattggt atcacattga tagcggacag ctacgcgcag
     3241 atgaactggc ccggtgtcat attccgtccg ctcaaagaac gcatccctgc agacttatat
     3301 attgtttatg aaacgcagca ggtgacgccc gcgctggtta aactgctggc ggcgttggcg
     3361 cagtagatga gaggcacggg aactgccgga catagttggt ctgacaagcg aagcgcatca
     3421 ggcaatttcg caaattgcag atagcaaaaa agcgccttta gggcgctttt ttacattggt
     3481 gggtcgtgca ggatgactcg cttcactcgc ccttcgggcc gtcgccgcga gcggctccgt
     3541 tgtttcgctg cgctcaactc
//
LOCUS       DACAOP010000206         3350 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.207, whole genome shotgun sequence.
ACCESSION   DACAOP010000206 DACAOP010000000
VERSION     DACAOP010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3350
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.207"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(254..781)
                     /gene="mobB"
                     /locus_tag="IT892_004505"
     CDS             complement(254..781)
                     /gene="mobB"
                     /locus_tag="IT892_004505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418293.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HAP3137616.1"
                     /translation="MAGKTMIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHT
                     HHDMDVDKPGKDSYELRKAGAAQTIVASQQRWALMTETPDEEELDLQFLASRMDTSKL
                     DLILVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLDINDVE
                     GLADFVVEWMQKQNG"
     gene            complement(763..1347)
                     /gene="mobA"
                     /locus_tag="IT892_004506"
     CDS             complement(763..1347)
                     /gene="mobA"
                     /locus_tag="IT892_004506"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HAP3137617.1"
                     /translation="MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALM
                     TQLSHVVVNANRHQEIYQASGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDT
                     PYIPPDLAARLNHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMVF
                     MRLAGGHAVDFSDHKDAFVNVNTPEELARWQEKR"
     gene            1417..1686
                     /locus_tag="IT892_004507"
     CDS             1417..1686
                     /locus_tag="IT892_004507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihD family protein"
                     /protein_id="HAP3137618.1"
                     /translation="MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELAD
                     LTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE"
     gene            1763..2749
                     /gene="srkA"
                     /locus_tag="IT892_004508"
     CDS             1763..2749
                     /gene="srkA"
                     /locus_tag="IT892_004508"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response kinase SrkA"
                     /protein_id="HAP3137619.1"
                     /translation="MNNSAFTFQTLHPDTIMDALFEHGIRVDSGLTPLNSYENRVYQF
                     QDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFY
                     FAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLF
                     EDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDL
                     DDARNGPAVQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVY
                     YLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY"
     gene            2766..>3350
                     /gene="dsbA"
                     /locus_tag="IT892_004509"
     CDS             2766..>3350
                     /gene="dsbA"
                     /locus_tag="IT892_004509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA"
                     /protein_id="HAP3137620.1"
                     /translation="MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEF
                     FSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALG
                     VEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKA
                     AADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQ"
BASE COUNT          832 a          814 c          835 g          869 t
ORIGIN      
        1 ctcagtcgga agactgggcc tttcgtttta tctgttgttt gtcggtgaac gctctcctga
       61 gtaggacaaa tccgccggga gcggatttga acgttgcgaa gcaacggccc ggagggtggc
      121 gggcaggacg cccgccataa actgccaggc atcaaattaa gcagaaggcc atcctgacgg
      181 atggcctttt tgcattggcg cagaaaaaaa tgccggatgc gacgctggcg cgtcttatcc
      241 agcctactct tgcttatccg ttctgctttt gcatccactc caccacaaaa tcagccagtc
      301 cctcaacatc attaatatcc agtaatgcga catcaagatt aagcggcaca tcactggcta
      361 cagcaataac atgcctgtct atcactaatt cttcaggtcg atgtccggct ccatcgcgaa
      421 acagcacaat ctttgcgatc tcttcatgct taaacccttc gaccagaatc aaatccagct
      481 ttgaggtatc cattcgactt gcgagaaact gtagatccag ctcttcttcg tctggtgttt
      541 ccgtcatcaa ggcccatcgt tgctggctgg caacgatggt ttgtgccgcg ccagccttgc
      601 gcagctcata gctatctttg cctggcttat caacatccat atcatggtgc gtatgcttaa
      661 tcagccctgg acggatccct ctggcgcata atgccgggat cagttttttc aaaagcgtag
      721 tttttccggt accactccac gcggcaaagg cgagtaacgg tatcatcgtt tttcctgcca
      781 tcgggcaagc tcctctggcg tattcacgtt aacaaatgca tctttatgat cgctgaaatc
      841 aaccgcatga ccgccagcca gacgcataaa taccattacc cggcgttctc ctgcttgcag
      901 atattccagt aataaaggct caatagcgcg gtttaccaga gcaatagtcg ggtgatcgcg
      961 ttcaccgtca tggacccaca cgacaggcgc atctttgcgc tgatgattaa gcctggctgc
     1021 taaatcaggg ggaatgtaag gcgtatcgca cgggcaaaac aaaaaccact caccagcttc
     1081 ctgctgcatt actgaaagca ttcctgccag agggcctggg taatccgcca gtgaatcttc
     1141 aatcactttc agaccgcttg cctgatagat ttcctgatga cgattagcat taaccacgac
     1201 gtgagagagc tgcgtcataa gcgcgtcagc gacatgttgc cataatggtt tgccgtttaa
     1261 ttcaagcaat cctttatcta cgccgcccat tcgtctggct ttaccgcctg ccagcacaac
     1321 gcctgttatc gtcgtcatca gattcaccga tatcgcctct tttattgtgg gattgaccct
     1381 gctaacgtgt ctgtctcaag agtaaggagc atcactatga aatgtaaacg tctgaatgaa
     1441 gttattgaac tcctccagcc agcctggcaa aaagagccag accttaacct gctgcaattt
     1501 ttgcagaaac tggcgaaaga gtcaggtttt gacggcgaac tggcggattt gacggatgac
     1561 attctgatct atcacctgaa aatgcgtgat tccgcgaaag atgcggtgat cccgggtttg
     1621 cagaaagatt atgaagaaga cttcaaaacg gcgctgttac gcgctcgcgg cgtaattaaa
     1681 gagtaaaagc ttgtaagcgg cgccaccaaa atcatcgtga aatgatatcc ttcgtcattc
     1741 gtaatgtttt ccggatgatg ggatgaataa cagcgctttt actttccaga cactacaccc
     1801 ggataccatc atggacgctc tgtttgagca tgggatccgg gtggattccg gtcttacccc
     1861 gcttaacagc tatgaaaacc gtgtctatca atttcaggac gaagatcgtc gacgttttgt
     1921 cgtcaaattt tatcgccctg aacgttggac agccgatcaa atcctcgaag aacatcaatt
     1981 tgcgttgcag ctggtaaatg atgaagttcc ggtcgcagca cctgtggcct ttaacggtca
     2041 gactttattg aatcatcagg gattttattt cgctgttttt ccaagcgtcg gtggtcgcca
     2101 gttcgaagct gataatatcg atcagatgga agcggttggg cgttatttag ggcgtatgca
     2161 ccagacgggg cgcaaacagc tttttatcca tcgcccgacc atcggtttga acgaatatct
     2221 cattgagcca cgcaagctgt ttgaggacgc tacactgata ccttccgggt tgaaagcggc
     2281 attcctgaaa gcgacagatg agctgattgc cgccgttaca gcacactggc gggaagattt
     2341 caccgttctg cggctacatg gagactgcca cgccgggaat attctctggc gcgatggtcc
     2401 aatgtttgtt gatctggatg atgcacgtaa tggtccagcc gttcaggatt tgtggatgtt
     2461 gctcaatggc gataaagccg agcagcggat gcaactggaa actattattg aagcttatga
     2521 agaatttagc gagttcgaca ccgctgaaat cggactgatt gaacctttac gcgccatgcg
     2581 tttggtttat tatcttgcct ggctaatgcg gcgttgggct gatcccgcgt tcccgaaaaa
     2641 tttcccgtgg ttaaccgggg aagattactg gctgcgacag acggcgactt ttatagaaca
     2701 ggcaaaagtt ctacaagaac cccctttgca attaacacct atgtattaat cggagagagt
     2761 agatcatgaa aaagatttgg ctggcgctgg ctggtttagt tttagcgttt agcgcatcgg
     2821 cggcgcagta tgaagatggt aaacagtaca ctaccctgga aaaaccggta gctggcgcgc
     2881 cgcaagtgct ggagtttttc tctttcttct gcccgcactg ctatcagttt gaagaagttc
     2941 tgcatatttc tgataatgtg aagaaaaaac tgccggaagg cgtgaagatg actaaatacc
     3001 acgtcaactt catgggtggt gacctgggca aagatctgac tcaggcatgg gctgtggcga
     3061 tggcgctggg cgtggaagac aaagtgactg ttccgctgtt tgaaggcgta cagaaaaccc
     3121 agaccattcg ttctgcttct gatatccgcg atgtatttat caacgcaggt attaaaggtg
     3181 aagagtacga cgcggcgtgg aacagcttcg tggtgaaatc tctggtcgct cagcaggaaa
     3241 aagctgcagc tgacgtgcaa ttgcgtggcg ttccggcgat gtttgttaac ggtaaatatc
     3301 agctgaatcc gcagggtatg gataccagca atatggatgt ttttgttcag
//
LOCUS       DACAOP010000207         3283 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.208, whole genome shotgun sequence.
ACCESSION   DACAOP010000207 DACAOP010000000
VERSION     DACAOP010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3283
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.208"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            86..628
                     /locus_tag="IT892_004510"
     CDS             86..628
                     /locus_tag="IT892_004510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137621.1"
                     /translation="MKKIALAGLAGMLLVSASVNAMSISGQAGKEYTNIGVGFGTEST
                     GLALSGNWTHNDDDGDVAGVGLGLNLPLGPLMATVGGKGVYTNPNYGDEGYAAAVGGG
                     LQWKIGNSFRLFGEYYYSPDSLSSGIQSYEEANAGARYTIMRPVSIEAGYRYLNLSGK
                     DGNRDNAVADGPYVGVNASF"
     gene            728..1930
                     /locus_tag="IT892_004511"
     CDS             728..1930
                     /locus_tag="IT892_004511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide deamidase-related
                     protein YfaY"
                     /protein_id="HAP3137622.1"
                     /translation="MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLTRRNTVG
                     DNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHEAWLKEMER
                     YFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVM
                     VEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPII
                     ELKLTGPASEQQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQNRQFSLTLSEQF
                     TSGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGFENEH
                     LNFALATPDGTFALRVRFSTTRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEV
                     VESMTLSV"
     gene            2150..2932
                     /locus_tag="IT892_004512"
     CDS             2150..2932
                     /locus_tag="IT892_004512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAP3137623.1"
                     /translation="MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYL
                     LLNELRRQRFLSLDHQENFCLWTKLVELSGHALSKMDLRELARPRLTQLMDTTGLLCH
                     LGIIDNGSAYYILKVESSATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGL
                     VWEQATPTTITHPQQLHEELARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAIS
                     VVGTRLQINEEYRDYLAGKAIACARDISRLLGWKSPFDLQAS"
     gene            2947..>3283
                     /locus_tag="IT892_004513"
     CDS             2947..>3283
                     /locus_tag="IT892_004513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416750.2"
                     /note="catalyzes the formation of
                     2-keto-3-deoxy-L-rhamnonate from L-rhamnonate; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnonate dehydratase"
                     /protein_id="HAP3137624.1"
                     /translation="MTLPKIKQVRAWFTGGATAEKGAGGGDYHDQGANHWIDDHIATP
                     MSKYREYEQSRQSFGINVLGTLIVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEG
                     KCVSDIKLIH"
BASE COUNT          765 a          810 c          890 g          818 t
ORIGIN      
        1 tttttcgctc attgaatcct ctgtgccagg cagtacaatc ccgcagcttt gggaattttg
       61 atttattgct tgtgggagag gggaaatgaa aaaaattgcg ctagcaggtc tggccggaat
      121 gctgttggtt tctgcatcgg tcaatgcaat gagcatcagc ggccaggcgg gtaaagaata
      181 caccaatatt ggtgtcggtt ttgggactga atcaacgggc ctggcgttaa gcggtaactg
      241 gacacataac gacgacgacg gtgacgtcgc gggcgtgggg ctggggttga atctacctct
      301 cgggccgtta atggcgaccg ttggcggaaa aggcgtttac accaacccga attacggcga
      361 tgaaggttat gccgcagcgg taggaggtgg tttgcagtgg aaaattggca acagcttccg
      421 tctgtttggc gagtattact actctccgga ttcgctctcc agcggtattc aaagttatga
      481 ggaagcgaat gctggcgcgc gttacaccat tatgcgtcca gtcagcattg aggcgggtta
      541 tcgctacctg aacctttctg gtaaagacgg taaccgcgac aacgcagtgg ctgacggccc
      601 gtatgttggg gttaacgcca gtttctgatc ccttccggcg cggcattctg ccgcgccatt
      661 cagtttctta ctacgcctta tctccctttg cgttatagtg attcgataac aaaagcagga
      721 gataaccatg ttaaaagtgg aaatgttatc caccggggat gaagtgttac acgggcaaat
      781 cgttgacact aacgctgcct ggctggccga ttttttcttt catcaggggt tgcctttaac
      841 tcgccgcaat acggtggggg ataaccttga tgacttagtc accattcttc gcgaacgtag
      901 tcagcacgcc gatgtgctga tcgttaacgg cgggctgggg ccgaccagtg atgatttaag
      961 tgcactcgcc gctgcgacag caaaaggtga aggcctggtg ttgcatgaag cctggctcaa
     1021 agagatggaa cgctatttcc acgaacgtgg acgagtaatg gcaccgagca accgtaaaca
     1081 agcggagcta cctgccagtg ctgaatttat caataacccg gtaggcaccg cctgtggttt
     1141 tgccgtgcag cttaatcgtt gcctgatgtt ctttaccccc ggcgtaccgt cagaatttaa
     1201 ggtgatggtc gagcacgaaa tcctgccgcg cctgcgcgag cgtttttctt taccgcagcc
     1261 gccggtttgc ctgcgtttga ctacctttgg tcgttcggaa agcgatctgg cacaaagcct
     1321 ggacactcta caattgccgc cgggcgtaac aatgggctat cgctcttcta tgccgattat
     1381 cgaactgaaa ctcaccggac cggcaagcga gcaacaggct atggaaaaac tgtggctgga
     1441 cgttaaacgt gttgccggac agagcgtgat tttcgaaggc accgaagggc tgcccgcgca
     1501 gatcagtcgc gaattgcaaa accgccagtt cagcctgacg ttgagcgagc aattcaccag
     1561 cggtttattg gctttgcaac tttctcgcgc aggtgctcca ttgctggcgt gtgaagtggt
     1621 tccttcacag gaagaaaccc tggcgcaaac tgcgcactgg attacagaac ggcgggccaa
     1681 ccattttgcc gggctggcac tggctgtttc gggtttcgag aacgagcatc tcaactttgc
     1741 gctagccacg ccagatggca ctttcgctct gcgtgtacgt ttcagcacta cacgctacag
     1801 cctggctatc cgtcaggaag tgtgcgcaat gatggcactg aatatgctgc gccgttggtt
     1861 aaacggtcag gacatcgcca gtgagcatgg ctggattgag gttgttgagt ccatgacttt
     1921 atctgtctga ttccgccact ctgtgccggt ttactgcacc ggcacattcc ccctccggcg
     1981 aaatttgtcc aacctgttgt actcaataag aaaaaatccg tgcgctgatt cacaaatttg
     2041 tgcgtaattt ctccagtccg ctggacgagg agtgggattt gatgcgcttc acaattttac
     2101 tccccctgag caacgagact gattccagta tctaagactg gagtccagta tgttggaatc
     2161 aagcaaagtt cccgccctga cacgggctat tgatattctc aatttgattg cccgcattgg
     2221 cccctgtagt gctgcgacga tcattgacac attggggatc cctaaaagca cggcctattt
     2281 gctgcttaat gaactcaggc gtcagcgttt tcttagcctt gatcaccagg aaaatttttg
     2341 tttgtggacc aagctggtgg agctttccgg tcatgcgtta agcaagatgg atctccggga
     2401 actggctcga ccgcgtttga cgcaactgat ggataccacc gggctgttat gtcacctggg
     2461 gattattgat aacggcagcg cttattacat tttgaaagtg gagtcatcag ccactatcag
     2521 cgtgcgttcc catgaaggaa aaagcctttc gctttatcgc tccggaatag gtaaatgcct
     2581 gcttgcctgg caacctgcag ctgtacagca aagtattatc gaagggctgg tctgggagca
     2641 ggcgacaccc acaacgatta ctcatccaca gcaacttcac gaagaactgg cgcgtattcg
     2701 ccgtcagggc tggagttatg acaacggcga agattatgcc gatgtccgtt gtgtcgctgc
     2761 cccggtgttt aacgccaata acgagcttac cgctgcgatt tcggtggtcg gtacccgctt
     2821 acaaatcaat gaagaatacc gtgattatct ggcgggcaag gccattgcct gcgccaggga
     2881 tatttcacgt ctgttgggat ggaaaagtcc ctttgactta caggcctcat aacaatggag
     2941 aacatcatga ccctaccaaa aatcaaacag gttcgcgcct ggtttactgg cggtgcgaca
     3001 gcagaaaaag gcgctggcgg cggtgattat cacgaccagg gggcaaatca ctggattgat
     3061 gatcatattg ccaccccgat gagtaaatac cgcgaatacg agcagtcccg ccagtcattt
     3121 ggcattaacg ttcttggcac gttgattgtt gaagttgaag cagaaaacgg ccagaccgga
     3181 ttcgctgttt cgacagccgg tgaaatgggc tgttttattg tcgaaaaaca tcttaaccgt
     3241 ttcattgagg gtaaatgcgt cagtgatatc aaactgatcc acg
//
LOCUS       DACAOP010000208         3266 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.209, whole genome shotgun sequence.
ACCESSION   DACAOP010000208 DACAOP010000000
VERSION     DACAOP010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3266
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.209"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(81..878)
                     /gene="mtfA"
                     /locus_tag="IT892_004514"
     CDS             complement(81..878)
                     /gene="mtfA"
                     /locus_tag="IT892_004514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgsA anti-repressor MtfA"
                     /protein_id="HAP3137625.1"
                     /translation="MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAE
                     RFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDE
                     WEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGD
                     RASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSE
                     YFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH"
     gene            972..1061
                     /locus_tag="IT892_004515"
     tRNA            972..1061
                     /locus_tag="IT892_004515"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1006..1008,aa:Ser,seq:cga)
     gene            complement(1631..2161)
                     /locus_tag="IT892_004516"
     CDS             complement(1631..2161)
                     /locus_tag="IT892_004516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416483.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HAP3137626.1"
                     /translation="MNRFSKTQIYLHWLTLLFVAITYAAMELRGWFPKGSSTYLLMRE
                     THYNAGIFVWVLMFSRLIIKHRYSDPSIVPPPPAWQMKAASLMHIMLYITFLALPLLG
                     IALMAYSGKSWSFLGFNVSPFVTPNSEIKALIKNIHETWANIGYFLIAAHAGAALFHH
                     YIQKDNTLLRMMPRRK"
     gene            complement(2504..3154)
                     /gene="zinT"
                     /locus_tag="IT892_004517"
     CDS             complement(2504..3154)
                     /gene="zinT"
                     /locus_tag="IT892_004517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HAP3137627.1"
                     /translation="MAIRLHKLAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGV
                     FDDANVQNRTLSDWDGVWQSVYPLLQSGKLDPVFQKKADADKTKTFAEIKDYYHKGYA
                     TDIEMIGIEDGIVEFHRNNETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPK
                     YIQFSDHIIAPRKSSHFHIFMGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH"
BASE COUNT          947 a          676 c          690 g          953 t
ORIGIN      
        1 attacttagc ggtaccttgt ctgtcaacac taaatttcat aagtcatttc aattggttaa
       61 ttaatctgca aagttgttaa ttaatgaaca ttcgtcgccg aaaacgagtc tgtatcatta
      121 gcgtgatgca gtctctgcaa aggatcttgt tgataaaatt ggcagaaacg ttgccacaat
      181 gaagggaaac gaggagcaaa aagttctggt gcgctaaaga aatattcaga aagtacggca
      241 aaacattcag caggatcact ggcagcataa gcatcaatgc tcgccgcatt ctcgccaacc
      301 aattcgattt cttcctgaat gttgttcatt gcagcatgaa gatcgtgttc ccagccagca
      361 acctcacgca acggaataaa gggaactccg ctggcgcgat cgccgttacg ggtgtccagc
      421 ttatgagcga cttcatgaat aatcaggtta aaaccagaag catcaaaaga atcttgtata
      481 tccaaccagt tcaaaacgat aggcccttgc tgccagctct gacctgactg aacaatacgt
      541 tggttatgca ccagaccgat atcgtcttcc cattcatcat cgaccacaaa tggcgcagga
      601 taaattaaga cttcatgaaa accatccagc cattccagtc ctaactccag aacgggtagg
      661 caaaatagaa gtgctatccg gcagcttctt aatgaatcca gttcaaagcc ctgtaaagga
      721 acaagccgct tttgctgtaa aaaacgttcg gcaagagtga ctaatttgct ttgttcctgt
      781 tccgtcagac acgttaaaag ggggatcgat agtgcttcct gccagggaag ggcagtttga
      841 tgtgctgatt cttgtacttt ccagggccac ttaatcatcg ttttgctcgc aaactcgtca
      901 cttgaacaaa attgcacgga cagggactgt taaaatgcca gatttcctgg catcatggca
      961 accatctgaa cggagagatg ccggagcggc tgaacggacc ggtctcgaaa accggagtag
     1021 gggcaactct accgggggtt caaatccccc tctctccgcc actttatcaa tgacttatct
     1081 cccgacttcc cgccttgctt ttcctaaaca gaacaatcgt agaatattct tgaagggtta
     1141 gatcgtcact gttttctgtt cgatactgtg acattcagca cttgattcgc tatggatctg
     1201 acaggaagct ttcgagcgaa aatgtgcagt tattcagtcg ttttcttatc gctcaccatt
     1261 attcttttag acattcatcc tatgaaactg ccgcaaagtt ggtggtggga actgaagttg
     1321 cgtagagaag gggtcaataa ttgagtcaaa aaaggaacgc ggccgtcaga ttaaagccgc
     1381 gggacaaagt ccataatttc caagagttgt tgaatttccc agcttttttg aaagcctttg
     1441 tatcatacta acaagtaaaa aaggtttaaa taccaaaatt aacctgtatt tttgataagt
     1501 cttaccattg tacgatttac acagtttctg ctcctccttg ttgatcgtgg aaagggtgca
     1561 ttgtgcactt gcgtaaacat ttatgacgcg ttgatgtcca tagtgcacat ttccttgtca
     1621 ggggatcgac ttatttgcgg cgaggcatca ttcgtaacag agtattatct ttctgaatgt
     1681 agtgatgaaa gagtgctgcg ccagcgtgag ctgcgattaa aaagtagcct atatttgccc
     1741 aggtttcgtg aatatttttt atcagtgctt taatttcgct gtttggggta acaaagggag
     1801 acacattgaa accaaggaaa ctccacgatt ttccactgta agccatcaaa gcaatcccca
     1861 gcagaggaag tgcaaggaag gttatataaa gcatgatgtg cattagcgaa gccgctttca
     1921 tttgccaggc aggtggcggt ggcacaatag aaggatcact ataacggtgt tttataatca
     1981 ggcgtgaaaa cattaacacc caaacgaata tacccgcatt gtaatgtgtt tctcgcatca
     2041 gcagataagt actactacct ttaggaaacc agccacggag ttccatcgcg gcataggtta
     2101 ttgcaacgaa aagcagcgtt aaccaatgta aataaatttg agtttttgag aatcggttca
     2161 tttttgaagc tcctgtgatt ttcacagtca agctatccca cgaaccttaa aaattcctta
     2221 tacagatgtg gttttaagaa tttgttattt aaaaaattga tagtgcacat tgtaaccagc
     2281 caatataagc aatggcgtga gcacaggtat ctttctctgt tggccgtatt gtgtatggaa
     2341 tccgttattg gttaactcaa tgcgggttag cttattaata tacagacacg tcatagtgat
     2401 gagcgtgtct gtagctagct tgcgttcagt ggcgtttgtg gatggaccag tggcagttat
     2461 gatgacttac taaagcggca tcgaggcgtt atcatgagaa tactcaatga gacatcattt
     2521 cctcgaccac ttcttcgcta ctcaactgat atggataata cgttggccag ttttccattt
     2581 catttaataa agattgctgt gaatcattac ccataaaaat atgaaaatga gatgattttc
     2641 gtggtgcaat tatatgatcg ctaaattgta tatatttagg ggctttgctt tcaggatctt
     2701 tacattcgaa taagtaacga acgcctttct tgcctgattt ataggtgagt attttgtatc
     2761 catcgtaatc atatttacac gatgttgttt cattatttct atggaattca acaatgccgt
     2821 cctcaatgcc aatcatctcg atatctgttg cataaccttt gtgataataa tctttaattt
     2881 cagcaaatgt tttagtttta tctgcatccg ctttcttctg aaagacgggg tcaagtttgc
     2941 cactttgcag taaaggataa acggattgcc agactccatc ccagtcactg agcgttcggt
     3001 tttgtacatt ggcatcatca aaaacaccat tagcagcttt ttgttcgacc tctgttaagg
     3061 gtttgccgtg tgagtgatga ccatgcgaaa aggcaggagc gctaacaata aagacaccta
     3121 aagcaacagc cagtttatga agacgaatcg ccaaaacagt ttcctccaga gttaatgtat
     3181 atgatgtgta atgttatatt gtaacatata acaaaatgca acaactctta ggaaacgaga
     3241 gcatggcttt ctcagttcta cttatc
//
LOCUS       DACAOP010000209         3218 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.210, whole genome shotgun sequence.
ACCESSION   DACAOP010000209 DACAOP010000000
VERSION     DACAOP010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3218
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.210"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            220..1032
                     /locus_tag="IT892_004518"
     CDS             220..1032
                     /locus_tag="IT892_004518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase NDM-5"
                     /protein_id="HAP3137628.1"
                     /translation="MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQ
                     RFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLLVDTAWTDDQTAQIL
                     NWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHS
                     LTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSL
                     GNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR"
     gene            1036..1401
                     /gene="ble"
                     /locus_tag="IT892_004519"
     CDS             1036..1401
                     /gene="ble"
                     /locus_tag="IT892_004519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bleomycin binding protein Ble-MBL"
                     /protein_id="HAP3137629.1"
                     /translation="MADHVTPNLPSRDFDVTEAFYAKLGFATSWKDRGWMILQRGGLQ
                     LEFFPYPDLDPATSSFGCCLRLDDLDAMVALVNAAGAEEKSTGWPRFKAPQLEASGLR
                     IGYLIDPDCTLVRLIQNPD"
     gene            1406..2044
                     /locus_tag="IT892_004520"
     CDS             1406..2044
                     /locus_tag="IT892_004520"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HAP3137630.1"
                     /translation="MPAKIKICGISTPEALDATIAARADYAGLVFYPASPRAVTSNVA
                     GALTSRAAGQIAMVGLFVDADDAVIADALVAAKLNALQLHGSESPERVAQLRARFGKP
                     VWKALPVASASDVARAAAYAGAADLILFDAKTPKGALPGGMGLAFDWSLLAGYRGALP
                     WGLAGGLNPTNVAEAIARTGAPLVDTSSGVESAPGVKDTDKITNFAFAVRLA"
     gene            complement(2055..3086)
                     /locus_tag="IT892_004521"
     CDS             complement(2055..3086)
                     /locus_tag="IT892_004521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocation (TAT) pathway signal
                     sequence domain protein"
                     /protein_id="HAP3137631.1"
                     /translation="MTASTIRLRRWLAGLALLLALPATSAVAQDFELPPVDEVFVLSA
                     QATAPDRIEVRWRIADGYYLYRHRTSVKADAAFTGATMALPKGKAYRDEFFGDVETYR
                     KELLGTLTGTPAAGASATTLTVKYQGCADAGVCYPPQTRTLKVALPGEAGAGGFGCKA
                     RGLHDYVVKNGSADHPNAEVKFALGDVVNTMIGCTNGETIMLCHDTSLPRPYSLGFRV
                     QGTEGLWMDVNKSIYLEGKSPQPHRWEPAEGWFAKYDHPLWKRYADLAAGAGHGGMDW
                     FVIHAFVEALKAKAPMPIDIYDALAWSAITPLSEQSIAEGNRTLDFPDFTRGQWRTRK
                     PIFALNDAY"
     gene            complement(3091..>3218)
                     /locus_tag="IT892_004522"
     CDS             complement(3091..>3218)
                     /locus_tag="IT892_004522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HAP3137632.1"
                     /translation="ALQERLRQLHPYELPELLAVEAASGLPEYLQWLAAESRPVN"
BASE COUNT          583 a          979 c         1030 g          626 t
ORIGIN      
        1 atggctccag atgacaaaca tgatctcata tcagggactt gttcgcacct tccttagaga
       61 aatttgctca gcttgttgat tatcatatgg cttttgaaac tgtcgcacct catgtttgaa
      121 ttcgccccat atttttgcta cagtgaacca aattaagatc atctatttac taggcctcgc
      181 atttgcgggg tttttaatgc tgaataaaag gaaaacttga tggaattgcc caatattatg
      241 cacccggtcg cgaagctgag caccgcatta gccgctgcat tgatgctgag cgggtgcatg
      301 cccggtgaaa tccgcccgac gattggccag caaatggaaa ctggcgacca acggtttggc
      361 gatctggttt tccgccagct cgcaccgaat gtctggcagc acacttccta tctcgacatg
      421 ccgggtttcg gggcagtcgc ttccaacggt ttgatcgtca gggatggcgg ccgcgtgctg
      481 ttggtcgata ccgcctggac cgatgaccag accgcccaga tcctcaactg gatcaagcag
      541 gagatcaacc tgccggtcgc gctggcggtg gtgactcacg cgcatcagga caagatgggc
      601 ggtatggacg cgctgcatgc ggcggggatt gcgacttatg ccaatgcgtt gtcgaaccag
      661 cttgccccgc aagaggggct ggttgcggcg caacacagcc tgactttcgc cgccaatggc
      721 tgggtcgaac cagcaaccgc gcccaacttt ggcccgctca aggtatttta ccccggcccc
      781 ggccacacca gtgacaatat caccgttggg atcgacggca ccgacatcgc ttttggtggc
      841 tgcctgatca aggacagcaa ggccaagtcg ctcggcaatc tcggtgatgc cgacactgag
      901 cactacgccg cgtcagcgcg cgcgtttggt gcggcgttcc ccaaggccag catgatcgtg
      961 atgagccatt ccgcccccga tagccgcgcc gcaatcactc atacggcccg catggccgac
     1021 aagctgcgct gagccatggc tgaccacgtc acccccaatc tgccatcgcg cgatttcgat
     1081 gtgacagagg cgttttatgc gaagctgggc tttgcgacga gttggaagga tcgcggctgg
     1141 atgatcctgc agcgcggcgg tttgcagctc gaattcttcc cctatcctga cctcgaccca
     1201 gctacgagct cgttcggctg ttgcctgcgg ttggatgatc tcgatgccat ggtggcattg
     1261 gtgaacgcgg cgggagccga ggaaaaaagc accggctggc cgcgcttcaa agctccgcaa
     1321 ctggaggcga gcggcctgag gatcggctac ctgatcgatc ccgactgcac gctggtgcgg
     1381 ctgatccaga accccgactg accgcatgcc cgcgaaaatc aagatttgcg ggatcagcac
     1441 acccgaggcg ctcgatgcga ccatcgcggc gcgggcggac tatgccgggt tggtgttcta
     1501 tccagcgtcg ccccgtgcgg ttacgtcgaa tgtcgcgggc gctttgacat cgcgcgcagc
     1561 tggccagatc gccatggtcg gtttgttcgt cgatgcggat gatgctgtca tcgccgacgc
     1621 actggtggca gccaagctga acgcgctgca gctgcacggt tcggaatcgc ccgaacgcgt
     1681 ggcccagttg cgcgcgcggt ttggcaagcc ggtgtggaag gcgctgcccg tcgccagcgc
     1741 cagcgatgtc gcacgcgccg cagcctatgc cggggcggcg gacttgatct tgttcgacgc
     1801 caagaccccc aaaggcgcgc tgcccggcgg catggggttg gcgttcgact ggtcgctgct
     1861 ggccggatat cgcggtgcct tgccgtgggg gctggcaggc gggctaaatc cgacgaatgt
     1921 tgccgaggcg attgcgcgca ccggagcgcc gctggtcgat acctccagcg gcgtcgaaag
     1981 cgcgccgggc gtcaaggata ccgacaagat taccaatttc gcctttgcgg tgcgcttggc
     2041 ctaaatcgcg tcgatcaata ggcgtcgttc agcgcaaaga tcggcttgcg ggtgcgccac
     2101 tgccctcggg tgaagtcggg aaaatctaac gtgcgattgc cctcagcaat cgattgttcc
     2161 gacagaggcg tgatcgcgct ccaggccagc gcgtcgtaaa tgtcgattgg catcggggcc
     2221 ttggccttca gcgcctcgac aaaagcgtgg atcacgaacc agtccatccc gccatgcccg
     2281 gcccctgccg ccagatcggc gtagcgtttc catagcgggt gatcgtattt cgcaaaccag
     2341 ccctcggcag gctcccagcg gtgcggctgt gggctcttgc cctccagata gatcgacttg
     2401 ttgacgtcca tccacagccc ctcggtgcct tgcacccgaa agccgagaga ataggggcgc
     2461 ggcagcgagg tgtcgtggca cagcatgatc gtttcaccat tagtgcagcc gatcatggtg
     2521 ttgaccacat cacccagtgc gaatttcacc tcggcgttgg gatgatcggc agagccgttc
     2581 ttgacgacat aatcatgcag cccgcgcgcc ttacagccga agccgccagc gcccgcttcg
     2641 cccggcaacg cgaccttcag ggtgcgggtc tgcggcgggt agcacacgcc ggcatcggcg
     2701 cagccctggt acttcacggt cagggtggtc gcgctcgcgc cggccgcggg cgtgccggtg
     2761 agggtgccga gcaattcctt gcggtaggtt tcgacgtcgc cgaagaattc gtcgcggtag
     2821 gccttgccct tcggcagcgc catggtcgcg ccggtgaagg cggcatcggc cttgaccgag
     2881 gtgcggtgcc ggtacaggta atagccgtcg gcgatccgcc agcgcacctc gatgcggtcc
     2941 ggcgcggtgg cctgcgcgga caggacgaag acctcgtcga ccggcggcag ttcgaagtcc
     3001 tgggcgacgg ccgaggtcgc gggcagcgca agcagcaggg cgagcccggc cagccagcgg
     3061 cgcaggcgga tcgtggatgc ggtcattggc tcagtttacc ggtcggctct cggcggccag
     3121 ccattgcagg tattcgggca ggccggacgc ggcttcgacc gcgagcagct ccgggagttc
     3181 gtagggatgc agttggcgca ggcgttcctg cagggcgg
//
LOCUS       DACAOP010000210         3203 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.211, whole genome shotgun sequence.
ACCESSION   DACAOP010000210 DACAOP010000000
VERSION     DACAOP010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3203
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.211"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..76
                     /locus_tag="IT892_004523"
     CDS             <1..76
                     /locus_tag="IT892_004523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137633.1"
                     /translation="LPSETYITCAEANEMAKTDSAQVA"
     gene            89..250
                     /locus_tag="IT892_004524"
     CDS             89..250
                     /locus_tag="IT892_004524"
                     /inference="COORDINATES: protein motif:HMM:NF027771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137634.1"
                     /translation="MGNASVASRDLKIEQSPELSAKVVEKLNQVCAKDPQMLLITAID
                     DTMRAIGKK"
     gene            complement(333..1421)
                     /locus_tag="IT892_004525"
     CDS             complement(333..1421)
                     /locus_tag="IT892_004525"
                     /inference="COORDINATES: protein motif:HMM:TIGR01414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HAP3137635.1"
                     /translation="MAAGAFEYQLKQQGKNWYLTSYQSVNEEDNSSEGNSESTETPTP
                     VLRPEAGSYVANLAAANTLFVMRLNDRAGETRYIDPVTEQERSSRLWLRQIGGHNAWR
                     DSNGQLRTTSHRYVSQLGGDLLTGGFTDSDSWRLGVMAGYARDYNLTHSSVSDYRSKG
                     SVRGYSAGLYATWFADDISKKGAYIDSWAQYSWFKNSVKGDELAYESYSAKGATVSLE
                     AGYGFALNKSFGLEAAKYTWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNIQTRL
                     GFRTFIRTQEKNSGPHGDDFEPFVEMNWIHNSKDFAVSMNGVKVEQDGASNLGEIKLG
                     VNGNLNPAASVWGMWACSWVIMATMTPQ"
     gene            complement(1434..2954)
                     /locus_tag="IT892_004526"
     CDS             complement(1434..2954)
                     /locus_tag="IT892_004526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HAP3137636.1"
                     /translation="MKLKKLPGFSLGLIALAVGNAYATQLLDDYSIISYMTDEESPIE
                     IKDNNPISNGEYLTTEDESHAVKVDDGVTGYINNASVMTSGDGSYGISVDSQNKVLYI
                     SDSDIKTSGSVSDKENGGITASAVVSEFGGTIFMNGDNSVESGGAYSAGLLSQVNDSE
                     KMVNNTRLETTDKTNIVTSGENAVGVLACSSPGESRTCVDAVDDEVSDSNSYEVISRA
                     DLKMNGGSITTNGINSYGAYANGKKAYINLDYVALETVADGSYAVAIRQGNIDIKNSS
                     ITTTGTKAPIAKIYNGGELFFSNVTAVSKQDKGISIDASNIDSQAKIALLSVELSSAL
                     DSIDVNKTTTDVSILNRSIITPGNNVLVNNTGGDLNIISSDSILNGATKLVSGTTTLK
                     LSENTIWNMKDDSVVTHLTNSDSIINLSYDDGQTFTQGKTLTVKGNYVGNNGQLNIRT
                     VLGDDKSATDRLIVEGNTSGSTTVYVKNAGGSGAATLNGIELITVNGDESPADAFR"
BASE COUNT          884 a          754 c          606 g          959 t
ORIGIN      
        1 tttgccgtca gaaacctata ttacttgcgc agaagccaac gaaatggcaa aaactgacag
       61 cgcacaggtt gcataaattg ttgcggtaat gggtaatgcc agcgttgcca gccgtgattt
      121 aaaaattgag caatctccgg aactgagcgc caaagtggta gaaaaactga atcaggtttg
      181 cgctaaagac ccgcaaatgc tgttgatcac ggcaattgat gacaccatgc gtgctatcgg
      241 caaaaaataa tatttcatat gtaccgcgtc gatgaatacg acgcggtttt ttagctaacg
      301 gcgggatcag aacttatatt tcaggcccac catcactgcg gtgtcattgt agccattatc
      361 acccagctgc acgcccacat tccccagacg ctggccgctg gattcaggtt gccatttacg
      421 ccaagtttaa tttcccccaa attactcgcc ccatcttgtt cgactttcac accgttcatt
      481 gagacagcaa aatctttact gttatggatc cagttcattt caacaaaagg ttcaaagtcg
      541 tcaccgtgcg gaccgctgtt tttctcctga gtacgaataa aggtgcggaa gccgagtcgg
      601 gtctggatgt tgttatttgc gtcattctca atacgtgagc cattggcttc cgtgtgcgca
      661 ttatgatcga cgcccatcca gatagcctgt gcctgtggct ggaagatcca cgtatatttc
      721 gccgcttcca gaccaaagga tttattcagg gcaaaaccgt aacccgcttc cagcgagacg
      781 gttgcacctt tcgcgctata ggattcatag gctaattcat cccctttcac cgagttttta
      841 aaccagctat attgcgccca ggagtcaatg tatgcgcctt ttttactgat gtcatcggca
      901 aaccaggtgg catacagccc tgcgctatag cctctgacac tccctttcga acgataatcc
      961 gacacgctgg aatgagttaa gttgtagtcg cgggcataac cagccatcac tcccaaacgc
     1021 caactgtcac tatcggtaaa accaccggtt aacagatcgc cccctaactg cgagacgtag
     1081 cgatgcgagg tcgttctcaa ctgtccgttg ctgtcacgcc aggcattatg cccgccaatt
     1141 tgacgtagcc aaagtcggct tgaacgctcc tgttcagtta caggatcgat gtagcgcgtt
     1201 tcacccgcac ggtcgttcag acgcataaca aaaagagtgt tagcagctgc caggttagcg
     1261 acgtaacttc cagcttcggg gcgcaggacg ggggtaggcg tttctgttga ttctgaattt
     1321 ccctctgagc tgttatcctc ctcattcact gactgataac ttgtcaaata ccagtttttg
     1381 ccttgttgtt ttagttgata ttcgaaagct ccagctgcaa tccttgcatc accttatctg
     1441 aaggcatctg ctggagattc atcgccattc acagttatga gttcgatccc gtttagcgtg
     1501 gccgcgccgc ttcctccagc atttttcaca tagacggtag ttgaacccga agtattaccc
     1561 tcaacaataa gtctgtccgt agccgattta tcatcaccta atacggtgcg gatattaagc
     1621 tgaccattat taccgacata attacctttt acggttaatg tttttccttg ggtaaatgtt
     1681 tgaccatcat catacgaaag attgataata ctgtctgaat tagtcagatg ggtaacaacg
     1741 gagtcatctt tcatattcca gattgtattt tctgaaagct tcagcgtggt tgtgccgctg
     1801 acgagtttag tcgctccatt tagaatagag tcggacgaaa ttatgtttaa gtcacctcca
     1861 gtattattaa ccagaacatt attaccaggt gtgataatac ttcgattaag gatacttaca
     1921 tccgttgtag ttttgttaac atcaatacta tccaaagcac ttgaaagttc aacacttaat
     1981 agtgctattt tggcttgaga atcgatattt gatgcatcaa ttgatattcc tttatcttgt
     2041 tttgataccg cggtgacatt ggaaaaaaat aactctccac cattgtatat ttttgcaatg
     2101 ggggctttag tgcctgttgt tgtaatagaa ctatttttta tatcaatgtt accttgtcga
     2161 atagcaactg cataacttcc atcagccaca gtttcaagtg ccacataatc taaattaata
     2221 tatgcttttt tcccattagc ataagcacca tagctattaa tgccattagt tgttatggaa
     2281 ccaccattca tttttaaatc agcacggcta ataacttcgt aactgttaga atcactaact
     2341 tcatcatcta cagcatcgac acatgttcga gactctccag gacttgaaca tgcaagaaca
     2401 cctactgcat tttccccaga ggtaacaatg ttcgttttat ctgtggtttc aagacgggtg
     2461 ttatttacca tcttttcaga atcattaacc tggcttaaaa gtcccgctga atatgcccca
     2521 cccgactcga ctgaattatc accattcata aagatggtgc caccaaattc actgactact
     2581 gcgctggctg ttatccctcc attttctttg tcagatacgc ttccagaggt cttaatatcg
     2641 ctatcgctta tatataatac tttgttttga ctatcaacag aaataccata agatccatca
     2701 ccactagtca tcacactggc attatttata tatccagtta caccgtcatc cactttcaca
     2761 gcatggcttt cgtcttcagt ggttagatac tctccattac ttatcggatt attatctttg
     2821 atttcaatcg gcgattcttc atcagtcata taggaaatta tactataatc atccaacaat
     2881 tgtgttgcat atgcattacc caccgccaga gcaataagtc ccaaactaaa cccggggagt
     2941 tttttcagtt tcatagatta accatccatt cattggatta acaaacattc ctggtcaaat
     3001 aacctatgag ctcagattac caaaacggag ggtaaagaca aaaacaaaag cacaaaaaat
     3061 ttaaatagat aaacagcgac aatatataaa tgataaataa gtcggcatta tcatttttca
     3121 ccttattttc atgacattga tcactttgag gtgacgattt tgtttaacaa ataactcttc
     3181 gacatcaaaa ttgttaatag ttg
//
LOCUS       DACAOP010000211         3163 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.212, whole genome shotgun sequence.
ACCESSION   DACAOP010000211 DACAOP010000000
VERSION     DACAOP010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3163
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.212"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            35..895
                     /locus_tag="IT892_004527"
     CDS             35..895
                     /locus_tag="IT892_004527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(3)-IId"
                     /protein_id="HAP3137637.1"
                     /translation="MHTRKAITEALQKLGVQTGDLLMVHASLKAIGPVEGGAETVVAA
                     LRSAVGPTGTVMGYASWDRSPYEETLNGARLDDEARRTWLPFDPATAGTYRGFGLLNQ
                     FLVQAPGARRSAHPDASMVAVGPLAETLTEPHELGHALGEGSPVERFVRLGGKALLLG
                     APLNSVTALHYAEAVADIPNKRWVTYEMPMLGRDGEVAWKTASDYDSNGILDCFAIEG
                     KPDAVETIANAYVKLGRHREGVVGFAQCYLFDAQDIVTFGVTYLEKHFGTTPIVPPHE
                     AVERSCEPSG"
     gene            908..1450
                     /locus_tag="IT892_004528"
     CDS             908..1450
                     /locus_tag="IT892_004528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP3137638.1"
                     /translation="MIIWINGPFGAGKTTLAKRLRDRRSKSLIFDPEEIGFVVKETVP
                     MPASGDYQDLPLWRGLTIAAVREIRRNYSQDIIIPMTLVHPDYLTEILDGVRRIDDQL
                     LHIFLTLNEDLLRHRIANQTMHPDPNRNAEIREWRLANVARCLAARERLPCTTRVLDS
                     GAHTSDELAAMVLDGIDGRT"
     gene            complement(1932..2123)
                     /locus_tag="IT892_004529"
     CDS             complement(1932..2123)
                     /locus_tag="IT892_004529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000951934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137639.1"
                     /translation="MAIALMGAGFSATDTSDAVNILYPITMTVQANKAWQASGLKKSF
                     FLPSHKKVRGGEKISYARL"
     gene            2147..2374
                     /locus_tag="IT892_004530"
     CDS             2147..2374
                     /locus_tag="IT892_004530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137640.1"
                     /translation="MVNSYSLSDDSGVMAAAAITHFLFGQAVFSYLNGWSVLIGPGTG
                     LDSTGCKYARDLMGLVAFTAFIVTFLFRGYS"
     gene            2425..>3163
                     /locus_tag="IT892_004531"
     CDS             2425..>3163
                     /locus_tag="IT892_004531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137641.1"
                     /translation="MSQLSQLRSPAAVQAAIDEFVQLGRTKFLARHGYGKSRDFLVRD
                     PKTGTDCDSKAIAGVAFGKQFPEQGPLTADSFSGGEATVVPALTRLGFRIIRIGEDWS
                     EEEVLATVEDYFDMLRAEAAGEPYNKSEHNQALRQLLNGRSKSSVELKHQNISAVLDA
                     LGLPYINGYKPRGNSQLLLRKSVHAYVLEHQQTVGALVDALEEVKLPGDKTYRAALVE
                     PPAREVLVRTPASLRQRLPRKFDYAARD"
BASE COUNT          638 a          909 c          931 g          685 t
ORIGIN      
        1 gtatagtgtt ttgcagttta gaggagatat cgcgatgcat acgcggaagg caataacgga
       61 ggcgcttcaa aaactcggag tccaaaccgg tgacctcttg atggtgcatg cctcacttaa
      121 agcgattggt ccggtcgaag gaggagcgga gacggtcgtt gccgcgttac gctccgcggt
      181 tgggccgact ggcactgtga tgggatacgc gtcgtgggac cgatcaccct acgaggagac
      241 tctgaatggc gctcggctgg atgacgaagc ccgccgtacc tggctgccgt tcgatcccgc
      301 aacagccggg acttaccgtg ggttcggcct gctgaatcaa tttctggttc aagcccccgg
      361 cgcgcggcgc agcgcgcacc ccgatgcatc gatggtcgcg gttggtccgc tggctgaaac
      421 gctgacggag cctcacgaac tcggtcacgc cttgggggaa ggatcgcccg tcgagcggtt
      481 cgttcgcctt ggcgggaagg ccctgctgtt gggtgcgccg ctaaactccg ttaccgcatt
      541 gcactacgcc gaggcggttg ccgatatccc caacaaacgg tgggtgacgt atgagatgcc
      601 gatgcttgga agagacggtg aagtcgcctg gaaaacggca tcggattacg attcaaacgg
      661 cattctcgat tgctttgcta tcgaaggaaa gccggatgcg gttgaaacta tagcaaatgc
      721 ttacgtgaag ctcggtcgcc atcgagaagg tgtcgtgggc tttgctcagt gctacctgtt
      781 cgacgcgcag gacatcgtga cgttcggcgt cacctatctt gagaagcatt tcggaaccac
      841 tccgatcgtg cctccgcacg aggccgtcga gcgctcttgc gagccttcag gttagaggcc
      901 gtcgacaatg ataatctgga tcaacggacc tttcggcgcc ggaaagacga cgctcgctaa
      961 gcggctgcgc gatcggcgtt ccaaatcgct gatctttgac cccgaggaaa tcgggttcgt
     1021 ggtgaaagaa acggtcccca tgccagcgag cggagactat caggatctcc ccttgtggag
     1081 gggacttacg atcgcggcgg tcagggagat tcgaaggaat tactcgcagg acatcatcat
     1141 cccaatgacg ctcgtgcacc cggactatct gactgagata ctcgacgggg taaggcggat
     1201 cgacgatcag ctgctgcaca tctttctgac gctcaacgag gacctattgc gtcaccggat
     1261 cgcgaaccag accatgcatc ctgacccgaa tcgaaatgcg gagattcgag agtggcgatt
     1321 agcgaatgtc gcccgatgct tggccgcaag ggaacggctt ccatgcacaa cccgtgttct
     1381 cgatagtggt gcacacacca gcgatgaact cgcagcgatg gtgctcgacg gaatcgatgg
     1441 gcgcacctga tcgccttcga cgcctgcgca aagcgtagcg cgagggtggc gggctcacga
     1501 ccaaacgccc agaggtcgat catcgcaggg atgtttggct ttgtggtgcg gacgacggga
     1561 ctcgaacccg tactctcaca gagaagcaga ttttcgtacc acctcgactt tcgccgccgt
     1621 ctgatgacgt tcgtggtctg gactgtccct tcgccattgc ccgaaggctt taggcgccgc
     1681 ccgtccagtc tctacacctt cccccgaagg ggcttggctc gggattggct tagggtattg
     1741 cccgttagcg ttccccgact ttgagcggtt ctactccgcg gatttccccg cgggcactcc
     1801 aattttaaag tctgctgcgt ctaccgattt cgccacgtcc gccttttttc gccgttccta
     1861 gcgctcgtgc gatgcaccta tgttgcacct agcgccgaat cgttcttcgt catcctgaaa
     1921 aaccacgtct cctaaagcct tgcatagctt atcttttctc caccacgaac ttttttgtgg
     1981 gatggtagaa aaaaagactt tttaagtccg ctggcttgcc aggccttgtt agcttgtacg
     2041 gtcatggtta tcgggtaaag aatattgacg gcatcgctgg tgtcggtggc tgaaaagccg
     2101 gctcccatca gggcaatagc catttcagat gcaggcgtac agggcaatgg tcaacagcta
     2161 cagcctgtct gacgattccg gcgtcatggc tgcggcggct atcacgcatt ttttgttcgg
     2221 tcaggcggtg ttttcgtacc tcaatggttg gagcgtgttg atcggacctg gtacaggttt
     2281 ggacagcacg ggctgcaaat acgcaaggga tttaatgggc ctggtggcgt tcacggcttt
     2341 tatcgtgacg tttctgttca ggggctactc ataatctcgt ggctcggcgg ttcccggcac
     2401 accatgacag taaggaagga ccctgtgtct caactctccc agcttcgaag ccccgccgcc
     2461 gtgcaggctg ccatcgatga gttcgtgcaa ctgggccgca cgaaattcct ggcgcgccac
     2521 ggctacggca agtcccgcga cttcctggta cgtgatccga agaccggcac cgattgcgat
     2581 tccaaggcca tcgccggtgt ggccttcggc aagcaatttc ccgagcaggg cccgctcact
     2641 gctgacagct tctccggtgg cgaggcgacc gtcgttccgg cgctgacgcg gctcgggttt
     2701 cgcatcattc gcatcggcga agactggtcc gaagaagagg tcctggccac ggtcgaagac
     2761 tatttcgaca tgctgcgtgc cgaggcggct ggggagccgt acaacaagtc cgagcacaac
     2821 caggcactgc gccaactgct gaacggtcgc agcaagtctt cagtcgagct caagcaccag
     2881 aacattagcg ccgtactcga tgccctgggc ctgccctata tcaacggcta caagccacgc
     2941 ggcaacagcc aactgctgct gcgtaaatcc gtacacgcct acgttctgga acatcagcag
     3001 acggtcggcg ctcttgtcga tgccctggag gaggtaaaac ttccgggtga caaaacctac
     3061 cgagcggctt tggtagaacc acccgcccgt gaagtgcttg tgcgtacccc ggcatctcta
     3121 cggcaacgcc taccgcgaaa gttcgattat gccgctcgcg atg
//
LOCUS       DACAOP010000212         3035 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.213, whole genome shotgun sequence.
ACCESSION   DACAOP010000212 DACAOP010000000
VERSION     DACAOP010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3035
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.213"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(72..566)
                     /locus_tag="IT892_004532"
     CDS             complement(72..566)
                     /locus_tag="IT892_004532"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP3137642.1"
                     /translation="MGLAQVKALDNIQEFEFDDEVAEQVENLQEKGNVKVTAIIQPEK
                     KSSLKSEFVMAFTSNLRALAELNISQSELKVITYILEIMEYGNLISLNQSQIARDLDM
                     KKSNMSVIFKKLTEKGVLIKEKGHLFMNSNLFAKGLNHKLNTERRENLKTAQFENDKF
                     TRSF"
     gene            complement(1029..1766)
                     /locus_tag="IT892_004533"
     CDS             complement(1029..1766)
                     /locus_tag="IT892_004533"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP3137643.1"
                     /translation="MGNSKRNIKKLNEDFRESILDYAISHNLKCAPGLIALYATGCRP
                     DEIETGIRVNFDSKNNKLRFKIVGSKLNYQQKRGIRIREVTVKVTEKNLQYYKPIIDI
                     FEKNPGAYDLKVKTESAKAFSGYITKISKKLWPRKKHHVSAYSFRHAKATELKNSEKF
                     DTEEIAKIMGHASVRSQESYGRKNKRSAGGFDDITEVETSTKPRGGDRLLRFKIKNKN
                     EATQKIKAVSTPTDTVVSTPPVRSLKR"
     gene            complement(1783..2730)
                     /locus_tag="IT892_004534"
     CDS             complement(1783..2730)
                     /locus_tag="IT892_004534"
                     /inference="COORDINATES: protein motif:HMM:NF013122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HAP3137644.1"
                     /translation="MESEDYDFMNIAELESDLDIISDDLQGIFDIEDLEEYMKGIDYG
                     YYINKTDFVYVDYIIEDPRITESLVYDFFDEIKNLYSDRKLELIQNSELYKKIKSKMD
                     ETADYDVERISEIVYKYQTLASNGFFVLDTETTDLNGEVVSFALIDEKNNILINEFCK
                     PIYNKISKTAESIHHISNEMIKNGRNIIDIYEDFLKIINSEENKNKPIFIYNEEFDIA
                     TIYRSLNFAKYEYKEIDEKGNNDFDNFELRTHCVMKDFAKFYGDFDDDYCSYNWKKLE
                     FAANYFGVKTDNLELHNSAVDCYLTLEVIKNMRDFFNKE"
BASE COUNT          917 a          528 c          401 g         1189 t
ORIGIN      
        1 aaaaaaaatc cccagattga tagaatttat tctattaatt tggggatttc gcctgtccgg
       61 cgaggacggt tttaaaatga tcttgtgaat ttatcgtttt caaattgtgc agtttttaaa
      121 ttctctcttc gttctgtatt taatttatga tttaaacctt tggcaaatag attagagttc
      181 ataaacaaat gtcctttttc ttttattaaa actcccttct ctgtgagttt tttaaatata
      241 acggacatat tagatttttt catatctaaa tctctcgcga tctgcgattg atttagacta
      301 attaaattgc cgtattccat aatttcgaga atatatgtaa ttacttttaa ttcgctttga
      361 cttatattta attctgctaa ggctcttaaa ttacttgtaa aagccataac aaattcgctt
      421 ttaagcgaac ttttcttttc tggttgaata atagcagtga cttttacatt tcctttttct
      481 tgtaaatttt ctacttgctc cgctacttca tcatcgaatt caaattcttg aatattatca
      541 agtgctttaa cttgtgctaa ccccataatt ttactccttt ttaaattgta taaactcagc
      601 tcctttataa tatattttgt gtactagtca ataacaaagt agaaaaaaat taaactttgt
      661 tatatgtctt tggactatag tccaatcctg atagttatga gatctcataa ctggagttat
      721 gagtttacat aacttcgagt tataagatta cataactgga gttatgagtt tacataactt
      781 ttttttgaaa aaaactatat ataacaatgt tttgacagta tgttaagaag taagaattaa
      841 taagaacata agaaaggaaa acaatccagg ctgtgccagt cggtagatcc aaccccaaaa
      901 cccatcggga aaaccatccc agttaccccg ttccggggcc ctgcttcgca atatggagga
      961 ttttgctata aaaccgtcct accggacagg tcaacccttc aaagccacac agcaagctgt
     1021 gtagcttctc agcgttttag agaacgaact ggaggtgtac ttactactgt atccgtaggg
     1081 gtagaaacag ctttaatttt ttgagtagct tcatttttgt tcttgatctt aaacctcagc
     1141 aatctatcgc ctcctcttgg ttttgtgctt gtttcgactt ctgttatgtc gtcaaatcca
     1201 ccggcacttc ttttgttctt tctcccgtaa ctttcttgag atcttacaga agcatgaccc
     1261 ataatttttg ctatttcttc tgtatcaaat ttttctgagt tttttaattc tgtcgctttt
     1321 gcatgtctaa aactatatgc agaaacatga tgtttttttc ggggccatag ttttttactt
     1381 atttttgtaa tgtatccgga aaacgctttt gcactttcag ttttaacttt taaatcataa
     1441 gcaccagggt ttttttcaaa aatatcaata ataggtttgt aatattgaag atttttttct
     1501 gtgactttta ctgtaacttc tctaattcta attcctcttt tttgctgata attaagttta
     1561 gaaccaacaa ttttaaatct taacttatta tttttactat caaaatttac tcttataccg
     1621 gtttcgattt cgtcaggtct acatcctgtt gcatataatg caataaggcc aggggcgcat
     1681 tttagattgt gcgatatcgc ataatctaaa atactctctc taaaatcttc gtttagtttt
     1741 tttatatttc tttttgagtt acccatatat aatttctctt ttttattctt tgttgaaaaa
     1801 atctctcata ttttttatta cttctaatgt taaataacaa tcaactgctg aattatgtaa
     1861 ctctaaatta tcagttttta caccaaaata attagctgca aactctagtt ttttccaatt
     1921 gtaagaacaa taatcatcat cgaaatcacc ataaaattta gcgaaatctt tcattacaca
     1981 gtgggttctt aattcgaaat tatcaaaatc attatttcct ttttcgtcga tttctttata
     2041 ttcgtatttc gcaaaattta gagatctata tattgtggca atgtcaaatt cttcattata
     2101 tataaaaatg ggtttgtttt tattttcttc gctatttatt atttttaaaa aatcttcata
     2161 tatatcaatt atatttctac cgtttttgat catttcgtta gaaatgtgat gaattgactc
     2221 agcagttttt gaaattttat tgtatatagg tttgcaaaat tcgttaatca atatattgtt
     2281 tttttcgtca attaaagcaa aactgacaac ttcgccattc agatctgttg tttcagtgtc
     2341 tagtacgaaa aagccattgc ttgcaagtgt ttgatattta tagacaattt ccgatattct
     2401 ttcaacgtca taatctgctg tttcatccat ctttgatttt atttttttgt ataattcgct
     2461 attttgtatt aactctaatt ttctatcaga atataaattt ttaatttcgt caaaaaaatc
     2521 atatactaaa ctttcagtaa ttctcggatc ttcgattata taatccacat aaacaaaatc
     2581 ggttttgttt atgtaataac cataatcaat gcctttcata tattcttcta aatcttcaat
     2641 gtcgaagatc ccttgcaaat catctgatat gatatctaaa tcactttcta attctgctat
     2701 attcataaaa tcataatctt cactttccat atttcacctc tttattgttt tttatattgt
     2761 taaattcaaa atccggaaat ttcaaaaatt cgcgttgctc aaatttgaaa taccgtaaaa
     2821 cccaaaccat ccccccatat taaatttatc gctctcgctc aaaattcaat atgaccccct
     2881 atgtaagggg gtggcatttt ccgatatgac gatgtcatac ctacaaatgc cgtgttgttc
     2941 caccccagga acggggttga aacaacaaaa acatataata gatataaccg ggtggaaatt
     3001 aatgtcaata ttcaaactgt ggagaaaata agaat
//
LOCUS       DACAOP010000213         2986 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.214, whole genome shotgun sequence.
ACCESSION   DACAOP010000213 DACAOP010000000
VERSION     DACAOP010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2986
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.214"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..327
                     /locus_tag="IT892_004535"
     CDS             <1..327
                     /locus_tag="IT892_004535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414796.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
                     /protein_id="HAP3137645.1"
                     /translation="NLFPATFSDGYVDIYGYHLPRPLHFGTQGEGMVGVRPEAITLSD
                     RGEESQRCVIRHVAYMGPQYEVTVEWHGQEILLQVNATRLQPDVGEQYYLEIHPYGMF
                     VLADAA"
     gene            complement(436..1368)
                     /gene="mmuM"
                     /locus_tag="IT892_004536"
     CDS             complement(436..1368)
                     /gene="mmuM"
                     /locus_tag="IT892_004536"
                     /EC_number="2.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase"
                     /protein_id="HAP3137646.1"
                     /translation="MSQNNPLRALLDKQDILLLDGAMATELEARGCNLADSLWSAKVL
                     VENPELIREVHLDYYRAGAQCAITASYQATPAGFAARGLDEAQSKALIGKSVELARKA
                     REAYLAENPQAGTLLVAGSVGPYGAYLADGSEYRGDYHCSVEAFQAFHRPRVEALLDA
                     GADLLACETLPNFSEIEALAELLTAYPRARAWFSFTLRDSEHLSDGTPLRDVVALLAG
                     YPQVVALGINCIALENTTAALQHLHGLTVLPLVVYPNSGEHYDAVSKTWHHHGEHCAQ
                     LADYLPQWQAAGARLIGGCCRTTPADIAALKARS"
     gene            complement(1355..2758)
                     /gene="mmuP"
                     /locus_tag="IT892_004537"
     CDS             complement(1355..2758)
                     /gene="mmuP"
                     /locus_tag="IT892_004537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414794.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-methylmethionine permease"
                     /protein_id="HAP3137647.1"
                     /translation="MQTTQQNAPLKRTMKTRHLIMLSLGGVIGTGLFFNTGYIISTTG
                     AAGTLLAYLIGALVVWLVMQCLGELSVAMPETGAFHVYAARYLGPATGYTVAWLYWLT
                     WTVALGSSFTAAGFCMQYWFPQVPVWVWCVVFCAIIFGLNVISTRFFAEGEFWFSLVK
                     VVTIIAFIILGGAAIFGFIPMQDGSPAPGLSNITAEGWFPHGGLPILMTMVAVNFAFS
                     GTELIGIAAGETENPRKVIPVAIRTTIARLIIFFIGTVFVLAALIPMQQAGVEKSPFV
                     LVFEKVGIPYAADIFNFVILTAILSAANSGLYASGRMLWSLSNERTLPACFARVTKNG
                     VPLTALSVSMLGGVLALFSSVVAPDTVFVALSAISGFAVVAVWLSICASHFVFRRRHL
                     QQGKALSELHYRAPWYPLVPVLGFVLCLVACVGLAFDPAQRIALWCGLPFVALCYGAY
                     FLTQPRNAKQEPEHVAE"
BASE COUNT          744 a          909 c          776 g          557 t
ORIGIN      
        1 aacctgttcc cggcaacctt cagcgacgga tacgttgata tctacggcta tcatctgccg
       61 cgcccgctgc actttggtac acagggtgaa gggatggtcg gtgtgcgccc ggaagcgatc
      121 acgctcagcg atcgcggcga agagagccag cgctgcgtga tccgccatgt cgcctatatg
      181 gggccgcagt atgaagtgac ggtggaatgg cacgggcagg agatattatt gcaggtcaac
      241 gctacgcgtc tgcaaccgga cgtcggcgag cagtattatc ttgaaatcca tccgtacggc
      301 atgtttgttc tggcggatgc ggcataacgt tttgtggttt tgtaggccgg ataaggcgct
      361 tgtgccgcca tccggcaatg cctgatgcgc tgcgcttatc aggcctacaa tgaacgatgt
      421 agacccgata aaccctcagc ttcgcgcttt taacgcggcg atatccgcag gcgtggtgcg
      481 acagcacccg ccaatcaacc gtgcgccagc ggcctgccac tgcggcagat aatccgccag
      541 ctgcgcgcaa tgttcaccgt gatgatgcca ggttttgctc acggcatcgt aatgctcgcc
      601 cgagttcgga tacaccacca gcggcagcac cgttaaaccg tgtaaatgct gcaacgcagc
      661 ggtggtgttt tccagcgcaa tacagttaat gcctagcgcc accacctgcg gataacccgc
      721 cagcaacgca accacgtcac gcagcggcgt accgtcgctc aggtgttcgc tgtcgcgcag
      781 ggtaaatgag aaccacgccc gcgcacgcgg atatgcggtc aacagctcgg ccaacgcctc
      841 aatctcggaa aaattcggca gggtttcgca ggccagcaga tcggccccgg catccagcaa
      901 ggcttccacg cgcgggcgat gaaacgcctg aaatgcctca acgctacaat gataatcgcc
      961 acggtattca gagccatccg ccagatacgc gccgtaaggc ccgacggatc ccgccaccag
     1021 aagcgttccc gcctgcgggt tctctgccag atacgcttca cgggctttac gcgccagctc
     1081 cacgcttttg ccaatcagcg ctttcgactg cgcttcatcc agacctcgcg cggcgaagcc
     1141 cgccggcgtc gcctgatagc tggcagtgat cgcgcattgc gcccccgccc ggtagtaatc
     1201 aagatgcact tcgcggataa gctccgggtt ttctaccagc actttggctg accacaggct
     1261 gtcggctaag ttacaccctc gcgcttccag ctccgtcgcc atcgcgccat ccagcagcag
     1321 gatatcctgt ttatcaagaa gagcgcgtaa cggattattc tgcgacatgt tctggctcct
     1381 gttttgcgtt tcggggttga gtaaggaaat aagcaccata gcacaacgca acaaacggta
     1441 acccgcacca caacgcaatt ctctgcgctg gatcgaatgc cagcccaaca caggccacca
     1501 ggcacagcac aaaacctaat actggcacca gcggatacca cggcgcgcga taatgtaatt
     1561 cactcaatgc cttaccttgt tgcagatgac ggcgacgaaa aacaaaatgc gaggcgcaga
     1621 tactcagcca caccgctacc accgcaaacc cggagattgc cgacagcgca acaaataccg
     1681 tgtccggggc caccacgctg gaaaacagcg ccagcacacc accgagcata ctgaccgaca
     1741 gcgccgtcag tggcacgccg tttttcgtta ctcgcgcaaa acaggccggt agcgtacgtt
     1801 cattcgacaa cgaccacagc atgcgcccgg aggcatataa cccggagttc gctgcagaaa
     1861 gaatagccgt caggatcacg aagttaaaaa tatcagcggc gtacgggatc cctactttct
     1921 caaataccag cacaaacggg cttttctcca cgcccgcctg ctgcatcggg atcagcgctg
     1981 ccagcacaaa cacggtgccg ataaagaaaa taatcagtcg cgcgatggta gtacgaatcg
     2041 ctaccgggat aactttgcgc gggttttccg tttcaccggc ggcaatgccg ataagttcgg
     2101 tacccgaaaa agcaaagttc actgccacca tagtcatcaa aatcggtaag ccaccgtgcg
     2161 ggaaccagcc ttctgccgtg atattactca gccccggcgc gggcgagcca tcctgcatcg
     2221 gaataaagcc gaaaatcgcc gccccaccga ggatgataaa ggcgatgata gtgaccactt
     2281 tgaccagcga gaaccagaac tccccttcgg caaaaaagcg cgtggagata acattcagac
     2341 caaaaataat cgcgcagaac accacgcacc agacccatac cggcacctgt ggaaaccagt
     2401 actgcataca gaatccagcg gcggtaaagc tcgaacccag cgccacggtc caggtcagcc
     2461 agtaaagcca ggccacggta tacccggtag ccggaccaag atagcgcgcg gcataaacgt
     2521 gaaacgctcc ggtctccggc atcgcgaccg acagctcgcc cagacactgc ataaccagcc
     2581 agaccaccag cgcaccaatc agataggcca gcagcgttcc cgccgctcca gtggtggaaa
     2641 tgatgtaccc ggtattgaag aataatcctg tgccaatcac gccgcccaag gaaagcataa
     2701 tcaggtgacg cgttttcatt gtgcgcttca gtggcgcatt ttgttgtgtt gtttgcatat
     2761 aaccttctaa acgtatggac atctaaacat ccaaagaagg tttgttatac cgcgtttgtt
     2821 aacagaatgc aaagtcaacc ctgcaccaga cgcagatgcc cgcgccgggc gcttaatagc
     2881 gggtggggat taataatcag atacaaaaag ggccgccagc tcataacgcc tccggaaggt
     2941 gcgaacaagt ccctgatatg agatcatgtt tgtcatctgg agccat
//
LOCUS       DACAOP010000214         2905 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.216, whole genome shotgun sequence.
ACCESSION   DACAOP010000214 DACAOP010000000
VERSION     DACAOP010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2905
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.216"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            559..1548
                     /locus_tag="IT892_004538"
     CDS             559..1548
                     /locus_tag="IT892_004538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001397210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP3137648.1"
                     /translation="MHKFTKALAAIGLAAVMSQSAMAENLKLGFLVKQPEEPWFQTEW
                     KFADKAGKDLGFEVIKIAVPDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKAR
                     GYDMKVIAVDDQFVNAKGKPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAV
                     MAITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPE
                     VKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLL
                     PSPDVHGYKSSEMLYNWVAKDVEPPKFTEVTDVVLITRDNFKEELEKKGLGGK"
     gene            1618..>2905
                     /locus_tag="IT892_004539"
     CDS             1618..>2905
                     /locus_tag="IT892_004539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose ABC transporter ATP-binding protein
                     AraG"
                     /protein_id="HAP3137649.1"
                     /translation="MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGA
                     GKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAEN
                     IYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALAR
                     NAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKD
                     GRYVKTFTDMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPIS
                     LAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMM
                     LCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPG
                     AEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRG"
BASE COUNT          773 a          665 c          748 g          719 t
ORIGIN      
        1 agtgcttttt gtatcttgtt gatattaatc aatgaatttg aattcatgat gaagtgatga
       61 ttttataaaa cgttttttca tttttgcgag atggctctca ttatacgtgt tctgttaatt
      121 aatgagcaca gtgataatta atgacgaaat gaatgacgtg cattttccac atctttgagt
      181 tgcggttatt acaccatttc aaaaactcaa cgccaggtaa tgcggcctat tgactggtta
      241 aaaagaagac atcccgcatg ggtaccaaag acaacaagga tttccaggct aatcttatgg
      301 attaatctgc tgtgcattcg acaatttgtc tgacaaattg gctttccctt atgtcttttc
      361 ccgctaaatt tatgcacgtt ctcactgtaa ttctgcgatg tgatattgct ctcctatgga
      421 gaattaattt ctcgctaaaa ctatgtcaac acagtcactt atcttttagt taaaaggtaa
      481 tgctttgttt tccgattaat ttaacgaatg tcattcgttt ttgccctaca caaaacgaca
      541 ctaaagctgg agagaaccat gcacaaattt actaaagccc tggcagccat tggtctggca
      601 gccgttatgt cacaatccgc tatggcggag aacctgaagc tcggttttct ggtgaagcaa
      661 ccggaagagc cgtggttcca gaccgaatgg aagtttgccg ataaagccgg gaaggattta
      721 gggtttgagg ttattaagat tgccgtgccg gatggcgaaa aaacattgaa cgcgatcgac
      781 agcctggctg ccagtggcgc aaaaggtttc gttatttgta ctccggaccc caaactcggc
      841 tctgccatcg tcgcgaaagc gcgtggctac gatatgaaag tcattgccgt ggatgaccag
      901 tttgttaacg ccaaaggtaa gccaatggat accgttccgc tggtgatgat ggcggcgact
      961 aaaattggcg aacgtcaggg ccaggaactg tataaagaga tgcagaaacg tggctgggat
     1021 gtcaaagaaa gcgcggtgat ggcgattacc gccaacgaac tggataccgc ccgccgccgt
     1081 actacgggat ctatggatgc gctgaaagcg gccggattcc cggaaaaaca aatttatcag
     1141 gtacctacca aatctaacga catcccgggg gcatttgacg ctgccaactc aatgctggtt
     1201 caacatccgg aagttaaaca ttggctgatc gtcggtatga acgacagcac cgtgctgggc
     1261 ggcgtacgcg cgacggaagg tcagggcttt aaagcggccg atatcatcgg cattggcatt
     1321 aacggtgtgg atgcggtgag cgaactgtct aaagcacagg caaccggctt ctacggttcc
     1381 ctgctgccaa gcccggacgt acatggctat aaatccagcg aaatgcttta caactgggta
     1441 gcaaaagacg ttgaaccgcc aaaatttacc gaagttaccg acgtggtact gatcacgcgt
     1501 gacaacttta aagaagaact ggagaaaaaa ggtttaggcg gtaagtaatt tgccggaaaa
     1561 attcccctct gcatgatgca gagggggtgt gaacgaccag tgattcacgg agacgttatg
     1621 caacagtcta ccccgtatct ctcatttcgc ggcatcggta aaacgtttcc cggcgttaag
     1681 gcgctgacgg atattagttt tgactgctat gccggtcagg ttcatgcgtt gatgggtgaa
     1741 aatggcgcag gaaaatcaac tctcttaaaa atcctcagcg gcaactatgc gccaaccacg
     1801 ggttctgtag tgattaatgg gcaggaaatg tccttttccg acacgaccgc agcacttaac
     1861 gcgggcgtgg cgattattta ccaggaactg catctcgtgc cagaaatgac cgtcgcggaa
     1921 aacatctatc tcggccagct gccgcataaa ggcggcattg tgaatcgctc attgctgaat
     1981 tatgaggcgg gtttacaact taaacatctt ggtatggata ttgacccgga cacgccgctg
     2041 aaatatctct ccattggtca gtggcagatg gttgaaatcg ccaaagcgct ggcgcgtaac
     2101 gccaaaatta tcgcctttga tgagccaacc agctccctct ctgcccgtga aatcgacaat
     2161 cttttccgcg ttattcgtga actgcgaaaa gaggggcggg taatcttata cgtttctcac
     2221 cgtatggaag aaatatttgc cctcagcgat gccattactg tctttaaaga tggacgttat
     2281 gtcaaaacct ttaccgatat gcagcaggtt gaccacgacg cgctggtgca ggcgatggtc
     2341 gggcgcgaca ttggcgatat ctacggctgg caaccgcgta gttatggcga ggagcgccta
     2401 cgtcttgatg ctgtgaaagc accaggcgtg cgtacgccaa taagtctggc ggttcgcagt
     2461 ggtgaaattg ttgggctgtt tggtctggta ggggcggggc gtagcgaatt aatgaaaggc
     2521 atgtttggcg ggacgcaaat caccgccggt caggtttata tcgaccaaca gccgatcgat
     2581 attcgtaaac cgagccacgc cattgccgca ggcatgatgc tctgcccgga agatcgcaaa
     2641 gcggaaggca ttattcccgt gcactccgtt cgcgacaata tcaacatcag tgccagacgt
     2701 aaacatgtgc tcggcggttg tgtaatcaac aacggttggg aagaaaacaa tgccgatcac
     2761 cacattcgtt cgctcaacat caaaacgccg ggcgcggagc aactgatcat gaatctctca
     2821 ggcggaaatc agcaaaaagc cattctgggc cgctggttat cggaagagat gaaggtcatt
     2881 ttgctggatg aacctacgcg cggca
//
LOCUS       DACAOP010000215         2864 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.217, whole genome shotgun sequence.
ACCESSION   DACAOP010000215 DACAOP010000000
VERSION     DACAOP010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2864
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.217"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            64..618
                     /locus_tag="IT892_004540"
     CDS             64..618
                     /locus_tag="IT892_004540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ib3"
                     /protein_id="HAP3137650.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLA
                     DVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQL
                     LANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTV
                     TTPDGPAVYMVQTRQAFERTRSDA"
     gene            885..2144
                     /gene="cmlA"
                     /locus_tag="IT892_004541"
                     /pseudo
     CDS             885..2144
                     /gene="cmlA"
                     /locus_tag="IT892_004541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001256773.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CmlA family chloramphenicol efflux MFS
                     transporter"
     gene            2336..2683
                     /locus_tag="IT892_004542"
     CDS             2336..2683
                     /locus_tag="IT892_004542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="HAP3137651.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     gene            2677..>2864
                     /locus_tag="IT892_004543"
     CDS             2677..>2864
                     /locus_tag="IT892_004543"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HAP3137652.1"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEI"
BASE COUNT          590 a          733 c          819 g          722 t
ORIGIN      
        1 aacgatgtta cgcagcaggg cagtcgccct aaaacaaagt taggcatcac aaagtacagc
       61 atcgtgacca acagcaacga ttccgtcaca ctgcgcctca tgactgagca tgaccttgcg
      121 atgctctatg agtggctaaa tcgatctcat atcgtcgagt ggtggggcgg agaagaagca
      181 cgcccgacac ttgctgacgt acaggaacag tacttgccaa gcgttttagc gcaagagtcc
      241 gtcactccat acattgcaat gctgaatgga gagccgattg ggtatgccca gtcgtacgtt
      301 gctcttggaa gcggggacgg atggtgggaa gaagaaaccg atccaggagt acgcggaata
      361 gaccagttac tggcgaatgc atcacaactg ggcaaaggct tgggaaccaa gctggttcga
      421 gctctggttg agttgctgtt caatgatccc gaggtcacca agatccaaac ggacccgtcg
      481 ccgagcaact tgcgagcgat ccgatgctac gagaaagcgg ggtttgagag gcaaggtacc
      541 gtaaccaccc cagatggtcc agccgtgtac atggttcaaa cacgccaggc attcgagcga
      601 acacgcagtg atgcctaacc cttccatcga gggggacgtc caagggctgg cgcccttggc
      661 cgcccctcat gtcaaacgtt gggcgcacaa taaggctcct cgcagagttg cttgaaagtt
      721 gttacgattc aaattcaatc atgagatagt cggcagatga gcatttccaa gaacgcagac
      781 aagtaagccg cagcaacctt catttttcgg ttgttgcggc gttctcaaga atccttttgc
      841 tctacgggag cgccgccaaa tcctttgttc aaggagatgg tttcgtgcgc tcaaaaaatt
      901 ttagttggcg gtactccctt gccgccacgg tgttgttgtt atcaccgttc gatttattgg
      961 catcactcgg catggacatg tacttgccgg cagtgccgtt tatgccaaac gcgcttggta
     1021 cgacagcgag cacaattcag cttacgctga caacgtactt ggtcatgatt ggtgccggtc
     1081 agctcttgtt tggaccgcta tcggaccgac tggggcgccg ccccgttcta ctgggaggtg
     1141 gcctcgccta ggttgtggcg tcaatgggcc tcgctcttac gtcatcggct gaagtctttc
     1201 tggggcttcg gattcttcag gcttgtggtg cctcggcgtg ccttgtttcc acgtttgcaa
     1261 cagtacgtga catttacgca ggtcgcgagg aaagtaatgt catttacggc atactcggat
     1321 ccatgctggc catggtcccg gcggtaggcc cattgctcgg agcgctcgtc gacatgtggc
     1381 ttgggtggcg ggctatcttt gcgtttctag gtttgggcat gatcgctgca tctgcagcag
     1441 cgtggcgatt ctggcctgaa acccgggtgc aacgagttgc gggcttgcaa tggtcgcagc
     1501 tgctactccc cgttaagtgc ctgaacttct ggttgtacac gttgtgttac gccgctggaa
     1561 tgggtagctt cttcgtcttt ttctccattg cgcccggact aatgatgggc aggcaaggtg
     1621 tgtctcagct tggcttcagc ctgctgttcg ccacagtggc aattgccatg gtgtttacag
     1681 ctcgttttat ggggcgtgta atacccaagt ggggcagccc aagcgtcttg cgaatgggaa
     1741 tgggatgcct gatagctgga gcagtattgc ttgccatcac cgaaatatgg gcttcgcagt
     1801 ccgtgttagg ctttatttct ccaatgtggc tagtgggtat tggtgtcgcc acagcggtat
     1861 ctgtggcgcc caatggcgct cttcgaggat tcgaccatgt tgctggaacg gtcacggcag
     1921 tctacttctg cttgggcggt gtactgctag gaagcatcgg aacgttgatc atttcgctgt
     1981 tgccgcgcaa cacggcttgg ccggttgtcg tgtactgttt gacccttgca acagtcgtgc
     2041 tcggtctgtc ttgtgtttcc cgagcggagg gctctcgcgg ccagggggag catgatgtgg
     2101 tcgcgctaca aagtgcggaa agtacgtcaa atcccaatcg ttgagagaat gtggcaagct
     2161 atcgcccaac aaatcgctgc agccgaccca aaaccgctac gcggtttcgg tcggctgagc
     2221 tcaggcgtta gatgcactaa gcacataatt gctcacagcc aaactatcag gtcaagtctg
     2281 cttttattat ttttaagcgt gcataataag ccctacacaa attgggagat atatcatgaa
     2341 aggctggctt tttcttgtta tcgcaatagt tggcgaagta atcgcaacat ccgcattaaa
     2401 atctagcgag ggctttacta agcttgcccc ttccgccgtt gtcataatcg gttatggcat
     2461 cgcattttat tttctttctc tggttctgaa atccatccct gtcggtgttg cttatgcagt
     2521 ctggtcggga ctcggcgtcg tcataattac agccattgcc tggttgcttc atgggcaaaa
     2581 gcttgatgcg tggggctttg taggtatggg gctcataatt gctgcctttt tgctcgcccg
     2641 atccccatcg tggaagtcgc tgcggaggcc gacgccatgg tgacggtgtt cggcattctg
     2701 aatctcaccg aggactcctt cttcgatgag agccggcggc tagaccccgc cggcgctgtc
     2761 accgcggcga tcgaaatgct gcgagtcgga tcagacgtcg tggatgtcgg accggccgcc
     2821 agccatccgg acgcgaggcc tgtatcgccg gccgatgaga tcag
//
LOCUS       DACAOP010000216         2759 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.218, whole genome shotgun sequence.
ACCESSION   DACAOP010000216 DACAOP010000000
VERSION     DACAOP010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2759
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.218"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..210
                     /locus_tag="IT892_004544"
     CDS             <1..210
                     /locus_tag="IT892_004544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001499638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAP3137653.1"
                     /translation="DRPDIAFRYYYKGVLWSPGYFASSCGGAPISVIRQYIEQQQTPG
                     QVENRALYPRPEGWGFTAHRIKSAI"
     gene            complement(228..896)
                     /locus_tag="IT892_004545"
     CDS             complement(228..896)
                     /locus_tag="IT892_004545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HAP3137654.1"
                     /translation="MRTTSFAKVAALCGLLALSGCASKITQPDKYSGFLNNYSDLKET
                     TSATGKPVLRWVDPSFDQSKYDSIVWNPITYYPVPKPSTQVGQKVLDKILNYTNTEMK
                     EAIAQRKPLVTTAGPRSLIFRGAITGVDTSKEGLQFYEVVPVALVVAGTQMATGHRTM
                     DTRLYFEGELIDAATNKPVIKVVRQGEGKDLNNESTPMAFENIKQVIDDMATDATMFD
                     VNKK"
     gene            complement(1198..1791)
                     /gene="tehB"
                     /locus_tag="IT892_004546"
     CDS             complement(1198..1791)
                     /gene="tehB"
                     /locus_tag="IT892_004546"
                     /EC_number="2.1.1.265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
                     /protein_id="HAP3137655.1"
                     /translation="MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRN
                     SLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNLHTRVVDLNNLTFDRQYDFILST
                     VVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYY
                     EGWERVKYNEDVGELHRTDANGNRIKLRFATMLARKK"
     gene            complement(1788..>2759)
                     /gene="tehA"
                     /locus_tag="IT892_004547"
     CDS             complement(1788..>2759)
                     /gene="tehA"
                     /locus_tag="IT892_004547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate transporter/tellurite-resistance
                     protein TehA"
                     /protein_id="HAP3137656.1"
                     /translation="NLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGLVILAMII
                     WGLLTSAFIARLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFRPLAVWLF
                     SFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALGYTDAGLV
                     FLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSVNGGEGDT
                     LAKMLFGYGLLQLLFMLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFF
                     HTLAVPLFIFTNFIIAILLIRTFALLMQGKLLVRTERAVLMKAEDKE"
BASE COUNT          762 a          702 c          617 g          678 t
ORIGIN      
        1 gatcgaccag atattgcatt caggtattac tacaaaggcg ttttgtggag tcctggctat
       61 tttgccagta gctgcggagg tgcgccaata tccgtcatcc gccaatacat tgaacaacag
      121 caaacacctg gtcaggtgga aaaccgcgcc ttatatcccc gccctgaagg atggggtttt
      181 acggcgcacc ggataaaaag cgccatctaa cgatggcgcg tctggaacta ctttttgtta
      241 acgtcaaaca tggtggcatc ggtcgccatg tcatcaataa cttgtttaat attttcgaaa
      301 gccattggcg tactttcgtt attcaggtct ttaccttcgc cctgacgaac gactttgata
      361 accggtttat tagtcgctgc atcaatcagc tcaccttcaa aatagaggcg agtatccatg
      421 gtacggtggc ctgtagccat ttgcgtcccc gcaaccacta atgcaacagg aaccacttca
      481 tagaattgca gcccttcttt gctggtatct acaccggtaa tggccccacg gaaaatcaga
      541 ctacgcggcc cagcggtggt aaccagtggt ttacgctgcg ctatcgcttc tttcatttcg
      601 gtgttggtat agttcaaaat tttatccaga actttctgcc ctacctgggt cgacggtttc
      661 ggtaccggat aataagtgat tgggttccag acgatgctgt catatttgct ttgatcaaaa
      721 ctcgggtcta cccaacgtaa aacaggttta cctgtagccg aggttgtttc ttttaaatca
      781 gagtaattgt ttaaaaaacc agaatattta tctggctggg tgattttaga ggcacaacca
      841 gacagagcca ataagccgca taaagctgca actttcgcaa atgatgtggt acgcatgaat
      901 agtttcctga gatgattata ttactttcta agttatagca aaaagcgccg cttcgtgttg
      961 tggcaaaaaa agtgttggtg aaaataaatt tttcagcccc ttttcagacg acatagtcaa
     1021 tgccgaaaaa ggggctaagt caatcatcag tacttaaatt tcagtaagtt aagctgctaa
     1081 aaacttcgac tactgtgatt aatttcacat cccttcgata aaaaatatgc ttaccgaaaa
     1141 gaagaacagt aaatcatctc agcgtgggga attttcacgc gttttgtgct taccgggtca
     1201 ttttttacgt gccagcatcg tggcgaaacg cagtttaata cgattaccgt tggcgtcggt
     1261 gcggtgcagc tcgccgacgt cttcattgta tttcaccctc tcccagcctt cgtaatatcg
     1321 acgtaattct ccctctttga aggcaaacgg gaagccgacg gtacatggat aatcagcggt
     1381 atccatcgcc gccacaatca ggttgtaacc accaggttta gtgcaacgtt gcatattggc
     1441 aatcaacccg gggatggttt tagcctcaag gaacatcagc accacagtcg aaagaataaa
     1501 atcgtactgt ctatcaaatg tgaggttatt cagatcaacg actcgggtgt gtaaattatc
     1561 cagattttca atggatttaa tgcgctcgac gttggcgata ctcatggcat ttttatccca
     1621 tgcgtcaaca tcataaccat tggcagccag gtaaagactg ttacgaccat tgccacagcc
     1681 cagatccagc gttttacccg gtttaaccac tttcaccgct tccagtactt cagagtgtgt
     1741 gcgggttaat tcatatttat cagtaaaata gttttcgtca cgaatgatca ttctttgtcc
     1801 tctgctttca ttaaaacggc gcgctcggtt ctgactaaca attttccctg catcagaagc
     1861 gcaaaagtac ggatgagcag tattgcaata ataaaattgg taaagataaa cagcggcacc
     1921 gccagcgtat ggaaaaatcc attatcgctg ccactcccca gatgcaaacc ggtggttgcc
     1981 agtgcagata cgccgaacga gaaactccag aatgaagcat taaatggctg ggagagatac
     2041 catggcatca gacgtagcat aaacagcagt tgcagcagtc cataaccgaa aagcattttc
     2101 gccagcgtgt caccctcgcc gccgttgacg ctcagccagg cactacaagc caccagcgca
     2161 ggagcgagct gaatgccgag tgatgtccgc agtgccgtgg gtaattctcc cgaactgcgc
     2221 agacgctgca agatcaccgg ttcaaggctt agccatgaga aaacgcctgc gcctaaaaac
     2281 accagaccgg cgtcggtgta gcccaacgca ccacaggcca ttgcgctgat aaagttgttg
     2341 gcaactgtcg gcagatacag tccaggcgtg gtagcttctt cagggtgaga tccgcgccat
     2401 aatcccgcag tttgccaggc ggcataagcc aactgaacca cgacaccaaa actgaacagc
     2461 cacaccgcca gtgggcgaaa ccacggaaca aaaccaatcg ccaccagcat cgtcgttgcc
     2521 ggaaacaaac tcacaaaact gctcagcact ggatggcgaa cttccgccag cacgctatgc
     2581 ggaaagcgta tgagtcgggc aataaatgcg ctagtcaata atccccagat gatcatcgcc
     2641 agaatcacca gcccatcccc taaccagtgg ctgacctgcc aaacctggct ggcatagcgc
     2701 caggcaaatc ccatccctat cgtccccaac acaataccaa agtagcctgc cggcaaatt
//
LOCUS       DACAOP010000217         2634 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.219, whole genome shotgun sequence.
ACCESSION   DACAOP010000217 DACAOP010000000
VERSION     DACAOP010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2634
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.219"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..308
                     /locus_tag="IT892_004548"
     CDS             <1..308
                     /locus_tag="IT892_004548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HAP3137657.1"
                     /translation="NREPPQAFISSSLPILEGTLSALRETYGFIPSDISIGTFDEHQM
                     LGFLPNAVWSMRQDEDAWAQHAFRLMQQKLQGENSDVKITVPMTLIQRPLSVEKRKG"
     gene            complement(357..785)
                     /locus_tag="IT892_004549"
     CDS             complement(357..785)
                     /locus_tag="IT892_004549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HAP3137658.1"
                     /translation="MSDNALCTPPRLNDSAICLRLAQFLQETEAAPQSTGLAIAVVGI
                     DGELIAFGAHARCPALPRQLAQRKAWSALRFRRPTARLAEEVCQGTLTLDIFDDKRLL
                     AMPGGAPVLVEGMAIGGVGISGLPPERDAELAEHFVQLLL"
     gene            complement(778..1683)
                     /locus_tag="IT892_004550"
     CDS             complement(778..1683)
                     /locus_tag="IT892_004550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HAP3137659.1"
                     /translation="MVNEKWSAFRGIISAVVTPMHADESVNYAALETLAHAQLARGVE
                     GFYCCGSSGEGPLLRFDERKQVLATLVNAAQGKVPVIAHVGTPRTQDAVELAKSAEQD
                     GASAVSLVPPYYYKYSREEIIAYYRRVLDAISIPVILYNIPQFTGVELDSLSAEALLG
                     DEQVLGVKHTSHNLYSLERMIARYPDKVFFNGFDEIFLSSLAAGATATVGTTVNLQPE
                     LFLALRTALRQGDIPKAQRLQQQINEVVENLVARGVFQSAKYLAGKGVVDTGPTREPF
                     VALTATQREDLDALHQRLQGYIADV"
     gene            complement(1677..2504)
                     /locus_tag="IT892_004551"
     CDS             complement(1677..2504)
                     /locus_tag="IT892_004551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004133472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP3137660.1"
                     /translation="MEDSLFSVKDKIIIVTGGLGQLGAQYVKTLHERGAKVAALATHV
                     DAARVDRVLGAIKDSDRLLCAEVNITDKASINQVLDKIEAKWGVPDGLVNNAGVDTQP
                     SAPPEVSGPFEDFPEEVFREVVEVNLVGTFLMTQQVGKRMRLAGKGGSIINVGSIYGV
                     VSPVQDIYSYKKEDTGIPFVKPVAYAAAKSGLYNFTRYCATYWGRDGIRVNTLTLSGV
                     ERSDQDPRFQKNYTNRIPIGRMAQPHEYNGAVVFLLSDASVYMTGSTVTVDGGWTAW"
BASE COUNT          534 a          826 c          727 g          547 t
ORIGIN      
        1 agaaccgcga gccgccgcag gcctttatct catcgtcgtt acccatcctg gaagggacgc
       61 tcagcgcact gcgggaaacc tacggtttta tcccctcgga tatctcaatc ggcaccttcg
      121 atgaacatca aatgctggga tttctgccca atgcggtttg gtcgatgcgc caggacgaag
      181 acgcttgggc gcagcatgcg tttcggctga tgcagcaaaa gctgcaaggg gaaaacagcg
      241 acgtcaaaat taccgtgccg atgacgctga ttcagcgtcc gctgtcggtg gaaaaacgta
      301 agggataaaa aagaagcggg cgaccgcgcc tcacaccggg ccgcccgtac agcgcgttaa
      361 agcagaagct gcacaaaatg ttcagccagc tccgcgtccc gttccggcgg caatccgctg
      421 atgcctacac cgccaatcgc catcccttcc accagtactg gtgcgccacc gggcatcgcc
      481 agcaaccgtt tatcgtcaaa gatgtccagc gttagggttc cctgacatac ttcttccgcc
      541 agtcgcgccg ttgggcggcg aaagcgcaat gcgctccagg ctttgcgttg tgccagttgc
      601 cggggcagag ctggacagcg ggcatgagcg ccgaaagcga tcagctcacc gtcgataccg
      661 accaccgcaa tcgccaggcc cgtgctctgc ggggccgctt ccgtctcctg taaaaactgc
      721 gccagccgca ggcagatcgc gctgtcgttc agtcgcggtg gcgtacagag cgcgttgtca
      781 gacatcagcg atatacccct gcaaacgctg atgcagtgcg tccagatctt cccgctgggt
      841 tgccgtcagc gccacaaacg gctcgcgggt cggcccggtg tccaccacgc ctttgcccgc
      901 cagatacttc gccgactgga acacgccacg cgccaccagg ttttccacca cctcgttaat
      961 ctgctgctgc aaacgctgcg ctttgggaat gtcgccttgc cgtaatgcgg tacgcagcgc
     1021 taggaacagc tccggttgca ggttcaccgt ggtaccaacg gtggctgtgg ccccggcggc
     1081 gaggctggac aggaagattt catcaaagcc gttaaagaac actttatcgg gataacgagc
     1141 gatcatgcgt tccagtgaat acaggttatg agaggtgtgc ttcaccccca gcacctgctc
     1201 gtcgcccagc agcgcttcgg cgctcaggct gtccagctcc acaccggtaa attgcgggat
     1261 gttatacaaa atcaccggga tcgagatggc gtccagtacc cggcggtagt aagcgataat
     1321 ctcctcgcgg ctgtatttat agtaataggg cggcaccagc gaaaccgcgc tcgccccatc
     1381 ctgctcggcg cttttcgcca gctccacggc atcctgagta cgcggtgtgc cgacgtgggc
     1441 aatcaccggc acctttcctt gcgccgcgtt gaccaacgtc gccagcacct gcttacgttc
     1501 gtcgaagcgc aacagcggcc cctccccgga ggagccacag cagtaaaagc cttccacgcc
     1561 acgtgccagc tgggcgtgcg ccagagtctc cagcgccgcg tagttaacgg attcatccgc
     1621 gtgcatcggc gtgactaccg cggaaataat gccgcgaaac gccgaccatt tttcgtttac
     1681 catgcggtcc agcctccatc cacggtgacg gtggagccgg tcatatacac ggaagcgtca
     1741 gagagcagga acaccaccgc gccgttgtac tcatgtggtt gcgccatgcg gccaattgga
     1801 atgcggttgg tgtagttctt ctgaaaacgt gggtcctggt cgctacgctc cacgccggaa
     1861 agcgtcagtg tattaacgcg aatgccgtcg cggccccagt aggtggcgca atagcgggtg
     1921 aagttataca gcccggactt ggccgccgcg taggcaaccg gcttcacaaa cgggatgccg
     1981 gtgtcctctt ttttgtagct gtagatatcc tgtactggcg aaaccacgcc ataaatcgag
     2041 ccgacgttaa tgatcgagcc gcctttgccg gctaggcgca tccgcttgcc cacctgctgg
     2101 gtcatcagga aagtacccac caggttcact tccaccacct cacggaacac ctcttcaggg
     2161 aaatcttcga acggaccgga aacttccggc ggcgcactcg gctgggtatc aacgcccgcg
     2221 ttgttcacca gaccgtccgg tacgccccat ttggcttcaa ttttatccag tacctgattg
     2281 atgctggctt tgtcggtaat gtttacttcc gcgcatagca gacggtcgga atctttaatc
     2341 gctcccagta cgcggtccac acgcgccgcg tcaacatgcg tcgccagcgc cgccaccttc
     2401 gcgccgcgct cgtgcagcgt tttcacgtac tgagcgccca gttgccccag gccgccagtc
     2461 acaatgatga tcttgtcttt taccgagaat aagctgtctt ccatttttcc tttcccctca
     2521 atatttatta gattttgtgt gcggcgaggt agtcacgatc gagaataatg ccgtggcccg
     2581 gtcggtcgct cggtatgtag tagccgtctt tctcaacacc ggcctcggcg atga
//
LOCUS       DACAOP010000218         2631 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.220, whole genome shotgun sequence.
ACCESSION   DACAOP010000218 DACAOP010000000
VERSION     DACAOP010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2631
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.220"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(205..1590)
                     /locus_tag="IT892_004552"
     CDS             complement(205..1590)
                     /locus_tag="IT892_004552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP3137661.1"
                     /translation="MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQL
                     DKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTLTGRVYDPAVQRPLRQTRTRKPF
                     PESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
                     DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYCQSEIYGRQGVELSRSLLSG
                     WVDACCRLLSPLEEALHGYVMTDGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNA
                     GSALAPAVRFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELYRNGGITEAACWAHA
                     RRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLES
                     WLREKMKTLFFGSGHGGERGALLYSLIGTCKLNDVDPESYLRHVPGVIADWPVNRVSE
                     LLPWRIALPAE"
     gene            complement(1640..1987)
                     /gene="tnpB"
                     /locus_tag="IT892_004553"
     CDS             complement(1640..1987)
                     /gene="tnpB"
                     /locus_tag="IT892_004553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019104956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAP3137662.1"
                     /translation="MIPLPSGTKIWLVTGITDMRNGFNGLAAKVQTALKDDPMSGHVF
                     IFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTQAQLAMLLEGIDW
                     RQPKRLLTSLTML"
     gene            complement(1984..2364)
                     /locus_tag="IT892_004554"
     CDS             complement(1984..2364)
                     /locus_tag="IT892_004554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HAP3137663.1"
                     /translation="MQKNVNPGRRKGCPNYPPEFKQQLVAASCEPGISISKLALENGI
                     NANLLFKWRQQWREGKLLLPSSESPQLLPVTLDAAAEQPESLAEDPETLSISCEVTFR
                     HGTLRFNGNVSEKLLTLLIQELKR"
BASE COUNT          558 a          740 c          696 g          637 t
ORIGIN      
        1 tttcaaattc atgtatgtga acaatattgg ggttccggcg tagaccccca atgaaagcgt
       61 caccacgtga aaacatgcct gcacggttta cacgtcatcc catggtggca gccggttaac
      121 tttcctgcgc caccagtgga aaaaggccat aagcagtccg aacaaaagta agcgtacagc
      181 gagggccgta ttgacgggga tgtgttattc agctggcagt gctatgcgcc acggaagcag
      241 ttcgctgacc cggttgaccg gccagtctgc tatgacgcca ggcacatggc gaaggtagct
      301 ttctggatcc acgtcattca gtttgcacgt cccgatcagg ctgtacagta gcgctccccg
      361 ctcaccacca tggccagagc cgaagaacag ggtcttcatc ttttcacgca accagctttc
      421 cagggatttc aacagcggtt tcgtttttcg ctgacgttca gcaagccgct gctctgccgg
      481 cattcccctt atatccgcct ctatggcgta caactgaccg atctgctcca gggcttcttc
      541 cgtcagtgct gacgggatgc ggacgtgcac atcgtggatc tttcggcggg catgagccca
      601 gcaggcagct tccgttatcc caccattgcg atacagctcg ttgaacccgg cgtacgcatc
      661 cgcttgcagc acaccgctga agcaagcaag atgagtctgc ggatggatgc cttttctgtc
      721 cgggctgtaa gcgaacctca ctgcaggtgc caacgctgac ccggcattgc ggtcatcacg
      781 aacatacgcc cacaaccgcc cggtcttcgt cttcttatta cccggcagca gtacctggac
      841 cggggtatca tcggcatgga gtttgccgtc agtcatgaca tagccatgaa gcgcctcttc
      901 cagcggagac agcagccggc agcatgcatc cacccagccc gacagcagtg aacggctcag
      961 ctccacacct tgccggccgt atatttctga ctggcaatac agcggggtgt gctctgcata
     1021 cttcgaggtc agcacgcggg ccagcagccc cggtccggcg ataccccgct cgatgggccg
     1081 cgaaggtgca ggtgcctgca cgatggcatc gcactgagta caggcatgtt tttcccgtac
     1141 cgtccggata acccggaagg cgctacgcat caactccagc tgttcggcgg tatcctcgcc
     1201 cagatagctc agtgaaccgc cgcagttcgg gcagcacggc gccgcaggca acagtcgctt
     1261 ttcgtcacgg ggtagtgatt cagggaacgg cttacgggtg cgggtctgac gcaacggacg
     1321 ctgtactgcc gggtcataca ccctaccagt cagcgtatcg ctctctttct gaagccggtt
     1381 cagatcggct tccatttgtg cgatacggcg ggagactttt tcggaacgac tgccgaagtt
     1441 catccggcgg agtttatcca gctgcgcctg cagatggtct atttcgcgct cccggttgct
     1501 cagcttttcc tgcagggcgt ggatcagcgc ttcctgttcg gccaggcgct gtttcagcag
     1561 gaagatgtcg tcagaagaga tgtcgttcat aagcccgtat tttaccgggc ttattctgtg
     1621 acaaccagga taaagagatt tacagcatgg tcagggaggt cagcagccgc ttgggctgtc
     1681 gccagtcgat accttccagc agcatcgcca gctgcgcctg cgtaaggaac actttgccat
     1741 cacgggctga cggccaggcg aagcgcccac gctccagccg tttggtcagg aggcacagtc
     1801 cgtcaccggt ggaccacagc agtttaacct gactgccgct gcggccccgg aaaatgaaaa
     1861 catggccgga catgggatcg tctttcagcg ccgtctgtac tttcgcagcc aggccgttga
     1921 agccatttct catatcggtg ataccggtaa ccagccaaat tttggtcccg gaaggtaacg
     1981 ggatcatcgc ttcagttcct gtatcagcag agtcaggagc ttttcgctga cattgccatt
     2041 gaagcggagc gtcccgtgcc ggaacgttac ctcacagctg atactgaggg tttccgggtc
     2101 ctctgcgagc gattctggct gttcggcagc tgcatcgaga gtcacaggaa gtagctgggg
     2161 gctctctgaa gaaggtaata gcagctttcc ctcacgccat tgttgtcgcc atttgaacaa
     2221 cagattggcg ttaatgccat tttcaagagc aagttttgag atggatatcc cgggttcaca
     2281 ggaggcagca acgagctgct gtttaaattc gggaggataa ttagggcagc cttttcgcct
     2341 gccgggattc acatttttct gcatatctga cactttggtt cccactactt atttggtgga
     2401 caccactttg tctaattcgt cagattctga ccagacggtt caggctgtac gcttaccccg
     2461 aagaggttat agactgtttc cgtagcatct cgttcacttg ctaatctttt ctctccttct
     2521 attctttcaa aaaatatttc agctgtttct ttatcatcat aagtatttaa taattccatt
     2581 atgattttcc tgattaatga attgatatca cgataattat atcatgaata g
//
LOCUS       DACAOP010000219         2563 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.221, whole genome shotgun sequence.
ACCESSION   DACAOP010000219 DACAOP010000000
VERSION     DACAOP010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2563
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.221"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..623)
                     /gene="pyrE"
                     /locus_tag="IT892_004555"
     CDS             complement(<1..623)
                     /gene="pyrE"
                     /locus_tag="IT892_004555"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAP3137664.1"
                     /translation="MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGR
                     DLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEA
                     KDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERG
                     RGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYR"
     gene            complement(688..1404)
                     /gene="rph"
                     /locus_tag="IT892_004556"
     CDS             complement(688..1404)
                     /gene="rph"
                     /locus_tag="IT892_004556"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006803115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAP3137665.1"
                     /translation="MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE
                     EGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAV
                     DLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVA
                     AVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLL
                     ALARGGIESIVATQKAALAN"
     gene            1531..2394
                     /locus_tag="IT892_004557"
     CDS             1531..2394
                     /locus_tag="IT892_004557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAP3137666.1"
                     /translation="MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRS
                     LEPVVRERIRSRLTRGKVECTLRYEPDVSAQGELILNEKLAKQLVTAANWVKMQSDEG
                     EINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIVARETEGQALKALIEQRL
                     EGVTAEVVKVRSHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVLLAQRIDVAEEL
                     DRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINAEVTNSAIELKVLI
                     EQMREQIQNIE"
BASE COUNT          601 a          724 c          638 g          600 t
ORIGIN      
        1 cgataggcct taaccgccgc cagatgttcc gccatttccg gcttctcttc caggtaagca
       61 atcagatctt tcagggtgat gatagagatc actttgcagt tgtaatcacg ctcaacttcc
      121 tgaatcgccg aaatctcgcc gcgcccccgt tcctgacgat cgagcgaaat caacacgcca
      181 gcaagcgtcg cgccattggc ctgaataatt tccatcgact cacgaatcgc cgttccggcg
      241 gtgatcacat catctaccag cattacgcgt ccttgtaacg cgctaccaac cagattgccg
      301 ccttcaccgt ggtcttttgc ctctttgcgg ttaaagcagt acggcaggtc caggtcatga
      361 tgctccgcca acgccacggc ggttgtggtg gcaatcggga tccctttgta agcagggcca
      421 aacagcagat cgaactcaat gccggagtcc accaatgctt cagcgtaaaa acggcctaac
      481 agtgccaggt cgcgcccggt attaaacagc ccggcgttga agaaataggg gcttttacgc
      541 ccggatttca gcgtaaactc gccaaacttt aacacctgct tgctaagcgc aaattcaata
      601 aactggcgct gatatggttt catgccttcg ctcctcatct tacttttcta cagacaaaaa
      661 aaagcgactc atcagtcgcc ttaaaaatca gtttgccagc gccgccttct gcgtcgctac
      721 aatggattcg attccccctc gggccagcgc caacaaggtg agtagctctt catgggtgaa
      781 cggctcgcct tctgccgtcc cctgcacttc aatgatgcgc ccgtcttcgg tcatcactac
      841 gttcatgtcg gtctctgcgg cagagtcttc aacgtattcc agatcgcaaa ccgcttcgcc
      901 gttcacaatc ccgacagaaa ccgcggctac catccctttc atcgggttgg ttttcagctt
      961 gccgttttcc accagcttct gtagcgcatc tgccagcgcc acacaggcac ccgtaatcga
     1021 agcggtacgc gtgccaccat cagcctgaag cacgtcgcag tccagcgtaa tggtgaactc
     1081 acccagcgct ttcaaatcta ctgccgcgcg aagcgcacgg gcgatcagac gctggatttc
     1141 cattgtgcgt ccaccctgct tacctttcgc cgcttcacga gcgttacggg tgtgggtaga
     1201 acgtggcagc atgccgtact ctgcggtgat ccagccctgg ccctgacctt tcaggaagcg
     1261 cggcacgcct tcttcaatag aggcggtaca caacactttg gtatcgccaa attcgaccag
     1321 caccgagcct tctgcatgtt ttgtatagtt acgagtcagg gtaacgggac gcacctgatt
     1381 attgctacgg cctgctggac gcatattgaa atctccggct tgaaacaaat gtggctgcgc
     1441 attatacgga cttccggcgg ttattcctat cctgacaagg catcgatggc tataatcctt
     1501 ccacctctcc ttttataaac aggaacgtct atgatccgca gtatgaccgc ctacgcccgg
     1561 cgtgaaatca agggtgaatg ggggagcgca acctgggaaa tgcgctcggt aaaccagcgt
     1621 tatctggaaa cttactttcg tctgccggag cagttccgta gccttgaacc tgtcgttcgc
     1681 gagcgtattc gttctcgcct gacgcgcggt aaagtggaat gtaccctgcg ctatgagcca
     1741 gatgttagcg cgcaaggtga gctgatcctc aacgaaaaac tggctaaaca gctggtaact
     1801 gccgcgaact gggtaaaaat gcagagtgac gaaggggaaa tcaacccggt tgatattcta
     1861 cgctggccgg gcgtgatggc agcccaggag caggatcttg acgccattgc cgctgaaatt
     1921 ctcgcggcgc tggatggtac gctggacgac tttattgtcg cgcgcgaaac cgaaggtcag
     1981 gcactgaaag cattgatcga gcagcgtctg gaaggcgtca ccgccgaagt ggtcaaagtc
     2041 cgctcccata tgccggaaat cctgcaatgg cagcgtgaac gcttggtcgc gaagctggaa
     2101 gatgctcagg ttcagttgga aaacaaccgt ctggagcagg agttggttct gctggcacaa
     2161 cgaattgacg ttgccgaaga actggaccgc ctcgaagcgc atgtcaaaga gacctacaac
     2221 attctgaaga aaaaagaagc cgttggtcgt cgtctggact ttatgatgca ggagttcaac
     2281 cgcgagtcga acactcttgc gtcgaagtct atcaatgccg aagtgacaaa ctccgcgatt
     2341 gagctgaaag tgttgattga gcagatgcgc gagcagattc agaatattga ataactcgta
     2401 acgccaattc ttacttttca gccttcacaa atgccgccca ctcaaacaga gcggcatttt
     2461 tcttccccgc aactttcaat tctgtttttc gtgccagctc cagattttgc gatgtttttt
     2521 tgcccagcac actgagaacg tgagatactc acaactgtat ata
//
LOCUS       DACAOP010000220         2538 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.222, whole genome shotgun sequence.
ACCESSION   DACAOP010000220 DACAOP010000000
VERSION     DACAOP010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2538
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.222"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..883)
                     /locus_tag="IT892_004558"
     CDS             complement(<1..883)
                     /locus_tag="IT892_004558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopN family type III secretion system gatekeeper
                     subunit"
                     /protein_id="HAP3137667.1"
                     /translation="MAIHVEHVGVLERAREVSRLEDIITEDNEDIEAEMPKMGDDPAG
                     KEARFLQATDEMSAALTQFMKKKIYEEQLANFLDGEEYVLEDQPIEKTDKVMEALKAA
                     TTHDYEVYSFAKKLFPDESELVVVLRAILRKKQISENVRLNAEALLKKVNQETTKKFI
                     NSGINSALKAKLFGQALSLNPKLLRASYRQFLMAEDDAVDTYVEWIGSYGYQNRILVT
                     KFIKETLFSDINALDASCSSLEFGMFLNKLSQLLSLQSAEALFLKTLMNNPIIKKFIS
                     AEDYWIFFLISLIKFPET"
     gene            complement(888..>2538)
                     /locus_tag="IT892_004559"
     CDS             complement(888..>2538)
                     /locus_tag="IT892_004559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="EscC/YscC/HrcC family type III secretion system
                     outer membrane ring protein"
                     /protein_id="HAP3137668.1"
                     /translation="NGLLTPGAYAATANGYVANKENLRSFFETVSSYAGKPTIVSKLA
                     MKKQISGNFDLTEPYALIERLSAQMGLIWYDDGKAIYIYDSSEMRNALINLRKVSTNE
                     FNNFLKKSGLYNSRYEIKGGGNGTFYVSGPPVYVDLVVNAAKLMEQNSDGIEIGRNKV
                     GIIHLVNTFVNDRTYELRGEKIVIPGMAKVLSTLLNNNIKQSTGVNVLSEISSRQQLK
                     NVSRMPPFPGAEEDDDLQVEKIISTAGAPETDDIQIIAYPDTNSLLVKGTVSQVDFIE
                     KLVATLDIPKRHIELSLWIIDIDKTDLEQLGADWSGTIKIGSSLSASFNNSGSISTLD
                     GTQFIATIQALAQKRRAAVVARPVVLTQENIPAIFDNNRTFYTKLVGERTAELDEVTY
                     GTMISVLPRFASRNQIELLLNIEDGNEINSDKTNVDDLPQVGRTLISTIARVPQGKSL
                     LIGGYTRDTNTYESRKIPILGSIPFIGKLFGYEGTNANNIVRVFLIEPREIDERMMNN
                     ANEAAVDARAITQQMAKNKEINDELLQKWIKTYLNREVVGG"
BASE COUNT          709 a          551 c          419 g          859 t
ORIGIN      
        1 ctgtctcagg aaattttatt aacgatatca gaaaaaatat ccaataatct tctgcgctaa
       61 taaatttttt aattattggg ttattcatta aagttttcag aaataaagcc tctgctgact
      121 gaagagacaa tagttgtgac aacttattga gaaacatacc aaattccaat gatgaacagc
      181 tcgcatcaag tgcatttata tctgagaaaa gcgtctcttt gataaatttt gtcaccagta
      241 ttctattttg atagccataa ctaccaatcc attcgacata agtatctaca gcatcgtctt
      301 ctgccattaa aaactgtcga taacttgccc ttagtaattt tggatttaat gacaacgcct
      361 ggccaaataa ctttgctttt aatgccgagt taataccgct attaatgaat tttttagtag
      421 tctcttgatt aactttttta agtaatgctt cagcgtttag ccgcacattt tcagatattt
      481 gttttttacg taaaattgca cgtaatacaa ccaccagttc gctttcatct ggaaataatt
      541 ttttagcaaa gctatacact tcatagtcat gggtagttgc tgccttaagc gcctccatga
      601 ctttatcggt tttttctatt ggctgatctt ccaggacata ttcttctccg tccagaaagt
      661 tggccagttg ttcttcgtag atttttttct tcataaactg cgttaacgct gctgacatct
      721 cgtcagtagc ttgtaagaat cgagcttctt taccggcggg atcatccccc attttaggca
      781 tttcagcttc aatatcttca ttatcttctg tgataatgtc ctctaagcga gaaacttctc
      841 tggctctttc taatacaccg acatgctcta catgaatcgc catttcacta tcctccgacg
      901 acttcacgat tcaggtaagt ttttatccat ttctgcagta attcatcgtt gatttcttta
      961 ttttttgcca tttgctgtgt tattgctctg gcgtcaaccg cagcctcatt cgcattattc
     1021 atcatgcgct catcgatctc tcttggctca ataagaaaga cacgaacgat gttattcgca
     1081 tttgttcctt catatccaaa taatttacca ataaatggaa tactgcctaa tattgggatc
     1141 ttacgacttt cataggtatt cgtatctcgt gtatatccac caatcaaaag acttttccct
     1201 tgaggcacgc gcgcaatagt acttataagc gttctaccaa cctgaggcag atcatcaaca
     1261 ttggtcttgt cggaattgat ttcattgcca tcttcaatat tcaagagtaa ttcaatttga
     1321 tttcgtgaag caaatcgtgg tagcacgcta atcatcgtac cataggttac ttcatccaac
     1381 tccgcagtac gctcgccgac taatttagta tagaaagtac ggttattatc aaatatagca
     1441 ggaatattct cctgtgttaa aacgacagga cgagcaacaa cggcggctct tcttttttgc
     1501 gcaagtgcct gtattgttgc aataaactgt gtcccatcca gggtactaat tgaacctgaa
     1561 ttattaaatg atgcacttag gctggatcca atttttatcg tgcccgacca gtcagctcct
     1621 aactgttcta gatcagtctt atcaatatct attatccata aagataattc aatatgtcgc
     1681 tttggaatat cgagcgtagc tactaacttc tcgataaaat caacctgaga tactgttcct
     1741 ttaacaagta aactgttggt atcaggatat gcaataattt gtatatcgtc agtctctggc
     1801 gctccagctg tcgatattat tttctctact tgtaggtcat catcttcttc agcaccagga
     1861 aaaggaggca tacgtgatac gttttttagt tgttgacgac ttgaaatttc agaaagtacg
     1921 ttaaccccag tgctttgctt aatgttatta tttaacaacg tcgatagtac ttttgccatg
     1981 ccaggaataa ctatcttttc gccacgtaat tcataagtcc gatcattaac gaatgtgttg
     2041 accagatgaa ttattcctac tttatttcgt ccgatctcga tgccatcgct gttttgctcc
     2101 attaatttcg cagcattaac gaccaggtca acataaactg gtggccccga tacatagaaa
     2161 gtaccattgc cgcccccttt aatttcataa cgagagttat acagacccga tttttttaaa
     2221 aaattattaa actcattcgt cgataccttt ctcagattaa tcagcgcatt acgcatctct
     2281 gatgagtcat agatataaat agctttgcca tcatcgtacc aaataagtcc catctgcgcc
     2341 gacaggcgtt caatcaaggc atagggttcg gttaaatcaa aatttccgct gatctgtttc
     2401 ttcatggcaa gcttacttac tattgtaggc ttacccgcat atgatgaaac cgtttcaaaa
     2461 aaactacgta gattttcttt atttgctacg tatccattcg ctgttgcggc atatgcacca
     2521 ggagtcaata atccatta
//
LOCUS       DACAOP010000221         2508 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.223, whole genome shotgun sequence.
ACCESSION   DACAOP010000221 DACAOP010000000
VERSION     DACAOP010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2508
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.223"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..225
                     /locus_tag="IT892_004560"
     CDS             <1..225
                     /locus_tag="IT892_004560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001682158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137669.1"
                     /translation="WPDLGGGSAVSQFAMMARKFGKQLIVAVSEKDAIKLKDNFDIIG
                     MLSYGKENFIAMSHTKSELTGGKRRYRIKN"
     gene            469..618
                     /locus_tag="IT892_004561"
     CDS             469..618
                     /locus_tag="IT892_004561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HAP3137670.1"
                     /translation="MTKYALIGLLAVCATVLCFSLIFRERLCELNIHRGNTVVQVTLA
                     YEARK"
     gene            902..1159
                     /locus_tag="IT892_004562"
     CDS             902..1159
                     /locus_tag="IT892_004562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="HAP3137671.1"
                     /translation="MSQTENAVTSSSGKKRPYRRGNPVPARERQKASLARRSATHKAF
                     HAVIQLRLKEKLSELADEDGITQAQMLEWLIESEVKRRKSL"
     gene            1395..1469
                     /locus_tag="IT892_004563"
     CDS             1395..1469
                     /locus_tag="IT892_004563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="HAP3137672.1"
                     /translation="MPGKVQDFFLCSLLLRIVSAGWCD"
     gene            1462..2319
                     /gene="repA"
                     /locus_tag="IT892_004564"
     CDS             1462..2319
                     /gene="repA"
                     /locus_tag="IT892_004564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
                     /protein_id="HAP3137673.1"
                     /translation="MTDLQQTYYRQVKNPNPVFTPREGAGTLKFCEKLMEKAVGFTSR
                     FDFAIHVAHARSKGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECG
                     LATESGAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTSALFAALDV
                     SEEAVAAARRSRVEWENRQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIK
                     RARARRDANRERQDIVTLVKRQLTREISEGRFTVNREAVKREVERRVKERMILSRNRN
                     YSRLATASP"
BASE COUNT          661 a          576 c          669 g          602 t
ORIGIN      
        1 tggcctgatt taggtggtgg atcagcagta tcacagtttg caatgatggc cagaaaattt
       61 ggtaaacaac ttattgtcgc tgtaagtgaa aaggatgcca tcaaattaaa agacaatttt
      121 gatattattg ggatgttgtc atatggtaaa gaaaatttta ttgccatgag tcatacgaaa
      181 agcgagttaa ctggagggaa acgtcggtac cggattaaaa attgatataa ataaaaagca
      241 tacttattgg ctggagtttc ggtagtaaaa agcgggaaat gaaggtaata gtcagcaaca
      301 gggaatgtgg tattatcgcg gcgggtgtct gagcctttct ggttcaggca agacgcaggt
      361 accagaaatg cgaagacccc actcgttaat ccattaactc gtgaggtctg catgaagtac
      421 cttaacacta ctgattgtag cctcttcctt gcagggaggt caaagtttat gacgaaatat
      481 gcccttatcg ggttgctcgc cgtgtgcgcc acggtgttgt gtttttcact gatattcagg
      541 gaacggttat gtgaactgaa tattcacagg ggaaatacag tggtgcaggt aactctggcc
      601 tacgaagcac ggaagtaagc tgccgggcgg ggacggaagt ccccgctttc cggaagtgtg
      661 aggtatttca ggggcagaca cccgacatgc cagaaacagc cggtcccgcc cggggccggc
      721 atcctggtta aggcatttcc tgcttttcag tcatttcatt atcaaaatca cattaaacgg
      781 ttgtaatcag acatgatttg tgcgccaaca ccgatcatcg tcacaacttt caagtcgctg
      841 atttcaaaaa actgtagtat cctctgcgaa acgatctctg tttgattatt gaggaggcga
      901 gatgtcgcag acagaaaatg cagtgacttc ctcatcggga aaaaaacgac cttacagaag
      961 gggtaatcct gttcctgcga gagaacgaca aaaagcgtct cttgcaagaa ggagtgccac
     1021 tcataaagcg tttcatgccg tcattcagct tcgactgaaa gaaaagttaa gtgagcttgc
     1081 tgatgaagac gggatcactc aggcacagat gcttgagtgg ctgatagagt cagaggttaa
     1141 gcgcagaaaa tctttgtgag tatttgcgtt tcttgctgtt tcagtgatga gatgttagat
     1201 tgctgatcgt tttaaggaat tttgtggctg gccacgccgt aaggtggcag ggaactggtt
     1261 ctgatgtgga tttacaggag ccagaaaagt aaaaaccccg ataatcttca ccaggtttgg
     1321 cgactaagag aagattaccg gggcccactt aaaccgtata gccaacaatt cagctatgcg
     1381 gggagtatag ttatatgccc ggaaaagttc aagacttctt tctgtgctca ctccttctgc
     1441 gcattgtaag cgcaggatgg tgtgactgat cttcaacaaa cgtattaccg ccaggtaaag
     1501 aacccgaatc cggtgtttac accccgtgaa ggtgcaggaa cgctgaagtt ctgcgaaaaa
     1561 ctgatggaaa aggcggtggg cttcacctcc cgttttgatt tcgctattca tgtggcgcat
     1621 gcccgttcga agggactgcg tcggcgcatg ccaccggtgc tgcgtcgacg ggctattgat
     1681 gcgctgctgc aggggctgtg tttccactat gacccgctgg ccaaccgtgt ccagtgctcc
     1741 atcaccacgc tggccattga gtgcgggctg gcgacagagt ccggtgcagg aaaactctcc
     1801 atcacccgtg ccacccgggc tctgacgttc ctgtcagagc tgggactgat tacctaccag
     1861 acggaatatg acccgcttat cgggtgctac attccgaccg atatcacgtt cacatctgca
     1921 ctgtttgctg ccctcgatgt atcagaggag gcagtggccg ccgcgcgccg cagccgtgtg
     1981 gaatgggaaa acagacagcg caaaaagcag gggctggata ccctgggtat ggatgaactg
     2041 atagcgaaag cctggcgttt tgtccgtgag cgtttccgca gttaccagac agagcttaag
     2101 tcccggggaa taaagcgtgc ccgtgcgcgt cgtgatgcga acagggaacg tcaggatatc
     2161 gtcaccctgg tgaaacggca gctgacgcgt gaaatctcgg aagggcgctt cactgtcaat
     2221 cgtgaggcgg taaaacgcga agtggagcgt cgtgtgaaag agcgcatgat tctgtcacgt
     2281 aaccgtaatt acagccggct ggccacagct tccccttgaa agtgacctcc tctgaataat
     2341 ccggcccgca ccggaggcat ctgcacgcct gaagcctgtc ggcgaacaaa aaaacagcac
     2401 tgcatacaaa aaacaaccta atcatccacc ttcaggtgca tccggtccct cctgtttttg
     2461 atacaaaaca cgcctcacag acgaggaatt ttgcttatcc acatttaa
//
LOCUS       DACAOP010000222         2455 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.224, whole genome shotgun sequence.
ACCESSION   DACAOP010000222 DACAOP010000000
VERSION     DACAOP010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2455
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.224"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            168..1709
                     /locus_tag="IT892_004565"
     CDS             168..1709
                     /locus_tag="IT892_004565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family transposase"
                     /protein_id="HAP3137674.1"
                     /translation="MPTVPISMRKLKEILRLKYGVGLSHRQIGRSLAISPSVVSRYAN
                     RAAQLGIKQWPLPTGWDDTKLKHAFLQTQVKMKKHSLPDWATVHRELRNKCVTLQLLW
                     EEYCERNPGGFYSYNHYCRMYREWLKTTSPSMRQVHKAGEKLFVDYCGPTVGVTDPET
                     GEIRTAQVIVAVLGASSYTWAEATWSQQLEDWVMSHVRCFQWLGGVPELVVPDNLKSA
                     TSRACKYDPDVNPTYQQMLEHYNVAVLPARPRKPKDKAKAEVGVQVVERWIMARIRHE
                     IFYSLASLNQRIRELLERLNNKIMQKLGYSRAELFIQLDKPALKPLPEASYSYTLVKK
                     VRVHADYHVEIDKHYYSVPCSLLGQQLEAWISGELVRLFNQGQEVAVHPRKRTYGYST
                     RNEHMPEAHRQHATWTPERLLEWAGHIGSETHSYVLHILNSRPHPEQSYRFCLGLLNL
                     HKKYSKARLNAACARALKTKVWRLSGIKSILEKGLDKQPVQDPKPDLLSTMEHENVRG
                     SEYYH"
     gene            1724..>2455
                     /locus_tag="IT892_004566"
     CDS             1724..>2455
                     /locus_tag="IT892_004566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP3137675.1"
                     /translation="MNHLYEQLTALKLTGFRDALKKQLAQPGTYQELGFEERLSLLTA
                     EELTCRENRKAERLIKHARFRLNAELSKLDYRNNRGLDRALIRSLSQGNWLTLKQNIL
                     LTGATGSGKTFLACALGHNACRQGYKVYYYRLKALMEQCYQGHADGRYSKLLTRLNNS
                     DLLLLDDWGLEPLSSEQRSDLLEIVDLMYQRGSIIVVSQLPVENWYKMIGDSTHADAI
                     LDRLVHGSIKIELKGESMRKIQSPLT"
BASE COUNT          698 a          580 c          587 g          590 t
ORIGIN      
        1 tcaataactt ccatcgagat cgggtaataa catttgaaca gatcgctgaa taacatcgat
       61 ggagatcact tttgactcat tttgttattc agtgatctcc atcaatgtta ttggaacttc
      121 acaggtgtgt tgatctgtat cttttgccat tccggtaaag gatacctatg ccaacagttc
      181 caatttctat gagaaaactt aaagaaattc ttaggcttaa atacggtgtt ggactcagcc
      241 atcgacaaat tggtcgtagt cttgcaatct ccccttccgt tgtatccaga tatgctaatc
      301 gggcggctca acttggcata aagcagtggc ccttacctac aggatgggat gatacaaaac
      361 taaaacatgc gttccttcag acccaggtta agatgaagaa gcactctctg cctgactggg
      421 ctacagtaca ccgggaactg cgtaataaat gcgtgacgct gcagctactc tgggaagaat
      481 actgtgagcg taatccaggc ggtttttaca gctataacca ttactgccgg atgtaccgtg
      541 aatggctcaa aaccacttca ccatcaatgc gtcaggtaca taaagctggc gaaaaacttt
      601 tcgttgatta ctgtggacct accgttggcg ttaccgaccc tgagaccgga gaaataagaa
      661 ctgctcaggt catcgtagct gttctcgggg catcaagtta cacatgggca gaggccacct
      721 ggtctcagca gcttgaagac tgggtgatga gtcatgttcg ctgcttccag tggttgggtg
      781 gcgttcctga acttgttgtt ccggacaatc tgaaaagcgc cacatccagg gcatgtaagt
      841 atgatcctga cgttaaccct acctaccagc agatgcttga gcattataat gtcgcagttt
      901 tgcctgcgcg gccacgtaaa ccgaaagata aagccaaagc tgaagttggc gttcaggttg
      961 ttgaacgctg gatcatggcc cgaatcaggc atgagatctt ctacagcctt gcatcgctta
     1021 atcagcgcat tcgggagttg ctggaaagac tgaataacaa aataatgcag aagttgggtt
     1081 attcacgtgc agaactcttc atccagcttg ataaacccgc actgaagcct cttcctgaag
     1141 ccagttacag ttacaccctg gtgaagaaag tcagagttca tgccgattac cacgtggaaa
     1201 tcgacaaaca ttactactcg gttccatgtt cgctgttagg ccagcaactg gaagcatgga
     1261 tctccggaga actggtaaga ctcttcaatc aggggcagga ggttgctgtg cacccgcgca
     1321 agcgtactta tggctacagt acccgcaacg agcacatgcc tgaagctcat cgacagcatg
     1381 ccacctggac gccagagcgt cttctggaat gggcggggca cataggcagt gaaactcata
     1441 gttatgtgct tcatatactg aactctcgtc cacatccgga acaaagctat cgcttctgcc
     1501 ttggactcct gaaccttcat aaaaaataca gtaaagccag acttaatgca gcatgtgcaa
     1561 gagctctgaa aacaaaggta tggcgtctgt caggtattaa atcgatcctg gaaaaaggtc
     1621 tggataaaca acctgttcag gatccaaaac cagatctgtt atccacgatg gaacacgaaa
     1681 acgtacgcgg cagtgagtat taccactgat acgggatcca atgatgaatc atctttacga
     1741 acaactgacc gcacttaaac tcaccggctt ccgtgatgcg cttaaaaagc aacttgctca
     1801 accgggcaca taccaggagc tgggcttcga agaacgcctg tcattactga cagcagaaga
     1861 actaacctgc cgtgaaaaca ggaaggcaga gcgtctgatc aaacatgcac ggttcagact
     1921 taatgctgag ttatcaaagc tggattatcg taacaataga gggctggaca gggccctcat
     1981 ccgttcactc agtcagggaa actggttaac cctgaaacaa aatattttac tgaccggggc
     2041 caccggcagc ggtaaaacgt tcctggcatg tgcacttggt cataatgcct gccgacaggg
     2101 atacaaggtc tactattatc gccttaaagc gctgatggaa cagtgctatc aggggcatgc
     2161 tgatggaaga tacagcaaac ttttgaccag gctgaataat agcgatctgc tgcttctgga
     2221 tgactggggg ctggaacctc tctcatcaga acagcgtagc gacctgctgg aaatagtgga
     2281 tctgatgtac caacgaggct caatcatcgt agtgagccag ttgccggtgg aaaactggta
     2341 caaaatgatc ggagactcta cacatgcgga tgccatccta gatcgactgg ttcatggcag
     2401 tatcaagatc gaacttaaag gagaatcaat gcggaaaata caatctccgt tgacc
//
LOCUS       DACAOP010000223         2454 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.225, whole genome shotgun sequence.
ACCESSION   DACAOP010000223 DACAOP010000000
VERSION     DACAOP010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2454
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.225"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..1314)
                     /gene="ag43"
                     /locus_tag="IT892_004567"
     CDS             complement(<1..1314)
                     /gene="ag43"
                     /locus_tag="IT892_004567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HAP3137676.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVTSELARSRGKRAGVAVALSLAA
                     VTSVPALAADTVVQTGETVSGGTLENHDNQIVFGTANGMTISTGLEYGPDNEANTGGQ
                     WIQNGGIANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQAVNTTLNGGEQWVHE
                     GGIATGTVINEKGWQAVKSGAVATDTVVNTGAEGGPDAENGDTGQTVYGDAVRTTINK
                     NGRQIVAAEGTVNTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASGTVVNSDGWQ
                     IIKEGGLADFTTVNQKGKLQVNAGGTATNVTLKQGGALVTSTAATVTGSNRLGNFTVE
                     NGKADGVVLESGGRLDVLEGHSAQKTRVDDGGTLAVSAGGKATGVTMTSGGALIADSG
                     ATVEGTNASGKFSIDGISGQASGLLLENGGSFTVNAGGQASNTTVG"
     gene            complement(1686..>2454)
                     /locus_tag="IT892_004568"
     CDS             complement(1686..>2454)
                     /locus_tag="IT892_004568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HAP3137677.1"
                     /translation="EPVIGIMGKSGAGKSSLCNALFQGEVTPVSDVHAGTREVRRFRL
                     SGHGHSMIITDLPGVGESRDRDAEYEALYRDILPELDLVLWLIKADDRALSVDEYFWR
                     HILHRGHQQVLFVVTQADKTEPCHEWDMAGIQPSPAQAQNIREKTDAVFRLFRPVHPV
                     VAVSACTGWELDTLVSALMTALPDHAASPLMTRLQDELRTESVRSQAREQFTGAVDRI
                     FDTAESVCIASVARTVLRAVRDSVVSVARAVWNWIFF"
BASE COUNT          510 a          749 c          628 g          567 t
ORIGIN      
        1 tccgacagtg gtgttgctgg cctgtccccc ggcattaacc gtaaagctgc cgccattttc
       61 cagcagcagg ccgctggcct gaccggatat gccatcaata ctgaacttac cgctggcatt
      121 ggtcccctca acagtggcac cactgtctgc aatcagggca ccaccggatg tcatggtgac
      181 acctgttgcc ttaccaccgg cagacactgc cagggttccg ccgtcatcca cccgtgtttt
      241 ctgcgctgaa tggccttcca gtacatccag gcgaccgccg gactccagaa caacgccgtc
      301 agccttaccg ttttccaccg tgaaattgcc cagacggttg ctgccggtga cggttgccgc
      361 cgtactggtg accagtgcgc ctccctgctt cagggtgaca ttcgtggctg taccaccggc
      421 gttcacctgc agcttgcctt tctggttaac ggtggtgaaa tccgccagac caccttcctt
      481 gataatctgc cagccgtcac tgtttacaac agtgccagac gccgtaccgc cgttgtgcac
      541 atactggtac cccccattca gcgtggtatc cagtgcgtga ccatgtacag tctggtcgcc
      601 gccggcataa accacagtgg tatttaccgt tccttcagca gccacaatct gacgaccatt
      661 tttattgatg gtggtgcgta cggcatctcc gtagacggtc tgcccggtat caccattttc
      721 tgcatccggt cccccttccg cgccggtatt cacaaccgtg tcggttgcca ctgcgccgga
      781 tttgacggcc tgccagccct tctcattaat gacagtaccc gttgcaatcc cgccttcatg
      841 tacccactgc tcaccgccgt tcagagtggt gttcactgcc tgcccctgaa ggctctgtcc
      901 gcctccggca ctgataaccg tgtctgaaac gcttcctccg gcattcactc tctgaagacc
      961 accaccggtg acagtagtgt tgttggcgat accgccattt tgtatccatt gtccgccggt
     1021 attggcctcg ttatccggcc catactccag accggtactg atggtcattc cgttggccgt
     1081 accgaagaca atctggttgt catgattttc cagtgttccg ccgctcacgg tttctcccgt
     1141 ctgtacaacc gtgtcagcag ccagtgccgg gactgatgtg acagcagcaa gagacagcgc
     1201 aaccgccaca ccggcgcgtt ttccccgtga gcgggccagt tcggaggtca ccaccagggt
     1261 gcccgtaatg tgattccata ccagcctgta gctggtgttc agatgtcgtt tcatcagctt
     1321 ttccttacag agggtgaata aaaaagccgg tacccacaaa tatgggtacc ggcaggtaca
     1381 aaacagcatg gtcagataaa gtggtttttc ccggacataa atgcttctcc tctctcatcc
     1441 gccagagaag tatcagtccg ttgtgtgcaa ttccgttctg catgatgaag agattcagct
     1501 gccttttcgc agaccattaa ccactataaa cgatcgatgg taacgatcga tacctgtttt
     1561 atcgatcgtt ttattctatt aacagcaagg cagtcacgca agagaaagag gtgggtatga
     1621 ggtgtttgtg tcatgttttc agttggttaa cgcaatgtaa tcaggcattt cccctggcag
     1681 agtgttcaga agaaaatcca gttccataca gcgcgggcaa cagagaccac cgagtcacgg
     1741 acggcacgca gaaccgtgcg tgcaacagag gcaatacaga cgctctccgc cgtgtcaaat
     1801 atccggtcca ccgcaccggt aaactgttca cgggcctgag accggacaga ttccgtgcgc
     1861 agctcgtcct gcaggcgggt catcagggga ctggcggcat ggtcgggaag cgctgtcatg
     1921 agcgcactga ccagcgtatc cagttcccag ccggtgcagg ccgatacggc cacaaccgga
     1981 tgtacgggcc ggaacagccg gaataccgca tctgttttct cacgaatgtt ctgtgcctgt
     2041 gcgggagaag gctgaatgcc ggccatatcc cattcatggc agggctccgt tttgtcggcc
     2101 tgcgtcacca caaacagcac ctgctgatgt ccccggtgca ggatgtgtcg ccagaaatac
     2161 tcatccacag acagggcacg gtcatcggct ttaatcagcc acagtaccag gtcaagttca
     2221 ggcagaatgt cacggtacag ggcttcatac tctgcatccc tgtcccggct ctcgcccacc
     2281 ccgggcaggt cagtgataat catgctgtga ccgtggccac tcagacggaa gcgccgcact
     2341 tcccgggtgc cggcgtgaac atcactgacc ggggtgacct ccccctgaaa cagtgcatta
     2401 cagagtgagg atttaccggc cccgctttta cccataatgc caatcacggg ttcg
//
LOCUS       DACAOP010000224         2429 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.226, whole genome shotgun sequence.
ACCESSION   DACAOP010000224 DACAOP010000000
VERSION     DACAOP010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2429
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.226"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..2287
                     /locus_tag="IT892_004569"
     CDS             <1..2287
                     /locus_tag="IT892_004569"
                     /inference="COORDINATES: protein motif:HMM:TIGR04346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DotA/TraY family protein"
                     /protein_id="HAP3137678.1"
                     /translation="TKNITRYLGSIFLLLSLTITQNAYAEGFDLFKPNDDNWLIKNIF
                     IPLFYPDTSPFSPISGVFLAGILAFGGVLAGYTMLAGTLNTAHDGEMLGKKWSSLWLP
                     VRTTLGVSMIMPIKGGFCAIQIIVVWLAVQGVGLADQTWNAFVENPLKGSVLPQPVID
                     RQISTLYQSAVSGYACIAAIKKDQGENEADGKSAGIIDKLLNITKEEWNPGVTTSTTS
                     GTNNGKKLVIEFGNKNREASRNACGSIIYDMYATSDKVIANAPQAALDLVDLNKIQRS
                     LIPVHVTALSALLARASDVGNRIANDDDSITADYIANDMKVAGEAYKVAIALAANTAY
                     QDSISKDTVESLKKDGFVSAGAWFIRIAMAQSAVNNVVNNVPIGTGVTGSMLEESTSW
                     FGGSDKTDYPSVDKIKKKVKTYFAKANMLNNNSASGAGAGTEGDQSLLDKLMAVFSPS
                     ELAALFTAQAFTANPVVAIINIGLSLINFALVTYGVMTTVVLGIGTAANVIPGGVISA
                     TTLVTPLVTGLLFALFWAGIRMAYVIAWKPFIVWFGAIIGWLVLVVESMFAAPLWMVA
                     HLAPDQDGVVGKMGQGYMLILSLILRPVLMVIGFVVALSLMTPCLMLINAFIAFTGDT
                     IGVGAAAFIGKIVMITIYLKVVEETMNKLFGLIHSIPDSILQWIGGGLSRSMGDYANG
                     IEGGSSHTTEKIGGGSKQAVMSMSSASTRGVQRAQELRERNEENTMNAANGHDGGGSG
                     NDKSSDNAPKTRSAGNTDTPE"
BASE COUNT          741 a          416 c          520 g          752 t
ORIGIN      
        1 tacaaaaaat ataacgaggt atttaggaag tatattctta cttctttcac taacaataac
       61 acaaaatgct tatgcagaag gatttgatct ctttaaacca aatgatgata actggttaat
      121 aaagaatata ttcattcctt tgttttatcc cgatacttcc cccttttccc ccatatctgg
      181 tgtcttcctt gcaggtatac ttgcttttgg tggtgttctt gctggttata ctatgcttgc
      241 cggcacactc aacacggctc acgatgggga gatgttaggt aagaaatggt cttctctctg
      301 gttgcctgtg agaacgactc ttggtgtctc tatgatcatg cctatcaaag gcgggttctg
      361 tgcaatacag attatcgtcg tatggcttgc agtgcaggga gtagggcttg cagatcagac
      421 ctggaatgct tttgttgaaa acccattaaa aggttctgtt ttgcctcaac ctgttattga
      481 cagacagatc agcacacttt accaaagtgc tgtaagtgga tatgcctgta tagcagctat
      541 taagaaagac cagggcgaaa atgaagctga cggaaaaagt gctggtatta ttgataaatt
      601 attaaacata acaaaagaag aatggaatcc aggagttaca acctcaacaa ccagtggcac
      661 taacaatggt aaaaaacttg ttatcgagtt tggtaataaa aatagagagg cttcaagaaa
      721 tgcctgtggt tctataattt atgatatgta tgctacttcc gataaagtta tagcaaatgc
      781 accccaggca gcacttgacc ttgttgatct taacaaaatt caaagaagct tgattcctgt
      841 tcatgtaaca gcattaagtg ctttattagc aagagcaagc gatgtaggaa acagaattgc
      901 taatgatgat gattctataa ccgctgatta catagctaac gatatgaaag ttgcaggtga
      961 agcctataaa gtcgctattg ctcttgcagc taatacggct taccaggatt caatttcaaa
     1021 agatactgtt gaatcattga aaaaagacgg gttcgtatca gcaggagcat ggtttatcag
     1081 aatcgcaatg gctcaaagtg ctgttaacaa tgtagtaaat aatgttccta ttggtacagg
     1141 tgttacaggt agtatgttgg aagaatcaac aagctggttt ggtggttctg ataaaacaga
     1201 ttatccttct gttgataaaa tcaagaaaaa ggtaaaaaca tactttgcaa aagcaaatat
     1261 gttgaataat aacagtgcaa gtggtgccgg tgcaggaaca gaaggtgatc aaagtctttt
     1321 agataagtta atggctgttt tctctccttc tgagcttgct gctcttttca ctgcacaggc
     1381 atttactgca aatccagttg tagcaattat caacattgga ttatctttaa ttaattttgc
     1441 tcttgtaaca tatggagtca tgacaactgt tgttttaggt attggtaccg ctgctaatgt
     1501 tatacctggt ggggttattt cagctacgac attggttaca ccattggtta caggactatt
     1561 atttgcactg ttctgggcag gaatcagaat ggcttatgtt attgcatgga aacctttcat
     1621 agtctggttc ggtgcgatta taggttggtt ggtgttagta gtcgaatcta tgtttgcagc
     1681 cccattatgg atggttgctc accttgcacc agatcaagac ggtgtagtgg gtaaaatggg
     1741 acaaggatac atgttgatac tgtctcttat cctccgtcct gttcttatgg ttatcgggtt
     1801 cgtagtagct ctatcactca tgaccccatg cttaatgttg ataaatgctt tcattgcttt
     1861 tactggcgat acgataggag tcggtgcagc cgctttcata ggtaaaatcg ttatgattac
     1921 gatctatcta aaagttgtag aagaaactat gaacaagctc tttggcttaa tccactctat
     1981 accagacagt attctacaat ggattggtgg tggtttatct cgctcaatgg gggattatgc
     2041 aaatggtatc gaaggtggtt cttctcacac gactgaaaaa atcggtggcg gtagtaaaca
     2101 agctgttatg agtatgagta gtgcatctac aagaggagta caaagggctc aggagcttag
     2161 ggaaagaaac gaagaaaata ccatgaatgc agctaacgga catgatggag gtggttctgg
     2221 aaatgataaa tcttctgata atgcaccaaa aacaagatca gcaggtaata cagatacacc
     2281 agaataaaat aaagcccctg aacttagggg ctttttgttt caatatagaa actaattaat
     2341 caacaatatt tacggagtta cttatggtaa cgactttaat atattctatt tattttcaaa
     2401 tatcaaatat ttttaaattt attttgccc
//
LOCUS       DACAOP010000225         2364 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.227, whole genome shotgun sequence.
ACCESSION   DACAOP010000225 DACAOP010000000
VERSION     DACAOP010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.227"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(277..678)
                     /gene="pemK"
                     /locus_tag="IT892_004570"
     CDS             complement(277..678)
                     /gene="pemK"
                     /locus_tag="IT892_004570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001398199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin
                     endoribonuclease PemK"
                     /protein_id="HAP3137679.1"
                     /translation="MLKYQLKNENGWMHRRLVRRKSDMERGEIWLVSLDPTAGHEQQG
                     TRPVLIVTPAAFNRVTRLPVVVPVTSGGNFARTAGFAVSLDGVGIRTTGVVRCDQPRT
                     IDMKARGGKRLERVPETIMNEVLGRLSTILT"
     gene            complement(611..868)
                     /gene="pemI"
                     /locus_tag="IT892_004571"
     CDS             complement(611..868)
                     /gene="pemI"
                     /locus_tag="IT892_004571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PemI"
                     /protein_id="HAP3137680.1"
                     /translation="MHTTRLKRVGGSVMLTVPPALLNALSLGTDNEVGMVIDNGRLIV
                     EPYRRPQYSLAELLAQCDPNAEISAEEREWLDAPATGQEEI"
     gene            complement(961..1614)
                     /locus_tag="IT892_004572"
     CDS             complement(961..1614)
                     /locus_tag="IT892_004572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001757010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP3137681.1"
                     /translation="MIQTRNQYLQFMLVMLAAWGISWGARFVMEQAVLLYGSGKNYLF
                     FSHGTVLMYLLCVFLVYRRWIAPLPVVGQLRNVGVPWLVGAMAVVYVGVFLLGKALAL
                     PAEPFMTKLFADKSIPDVILTLLTIFILAPLNEETLFRGIMLNVFRSRYCWTMWLGAL
                     ITSLLFVAAHSQYQNLLTLAELFLVGLITSVARIRSGGLLLPVLLHMEATTLGLLFG"
BASE COUNT          628 a          614 c          565 g          557 t
ORIGIN      
        1 tctcgagtat ttagttaaga aactgatagg tcagtatttg catcaatgtt cattgaattt
       61 gtatccgaag tcaatctgat gtaggaactt caaaactgcg caaaacacgc aaatacgcac
      121 aagaaagtag ggctgcgctt ggaattcgga aaataaacca catcaaaact actttttagc
      181 caaataacgt ttgggaatca ccagaatggt gggacaacag cggttttagt gccctaaatc
      241 gtacgttttc atccagttgc ccctcaaacc ccatgttcaa gtcagaatag tggacaggcg
      301 gccaagaact tcgttcatga tagtctccgg aacccgttcg agtcgttttc cgccccgtgc
      361 tttcatatca attgtccggg gttgatcgca acgtacaaca cctgtggtac gtatgccaac
      421 accatccaac gacaccgcaa agccggcagt gcgggcaaaa ttgcctccgc tggttacggg
      481 cacaacaaca ggcaggcggg tcacgcgatt aaaggccgcc ggtgtgacaa tcagcaccgg
      541 ccgcgttccc tgctgctcat gacctgcggt aggatcaagc gagacaagcc agatttcccc
      601 tctttccatg tcagatttcc tcctgaccag tcgccggtgc atccagccat tctcgttctt
      661 cagctgatat ttcagcattc ggatcacact gtgccagtag ctcagccagt gaatattgcg
      721 ggcgtctgta cggctcaaca atcagccggc cattatcaat gaccatgcca acttcattat
      781 ctgtgcccag agacagcgca ttcagcagtg ccggtgggac ggtcagcata actgagccgc
      841 caaccctctt cagtcgggtg gtatgcattc ttcacctcca taaaagttat atttaaatat
      901 aacatccact aaaaaaacac accaggcttt aacgcacaat gtttaataaa aatataactt
      961 tcaaccaaac agtaaaccca gcgtggttgc ttccatatgc agcaataccg gcagcagcag
     1021 gccaccactt ctgatcctgg ccactgatgt aatcaacccc accaggaaca gttctgccag
     1081 tgtcagcagg ttctgatact ggctgtgcgc ggcgacgaac aacaacgacg ttatcagcgc
     1141 ccccagccac atcgtccagc agtaccgtga acggaagacg ttcagcataa tcccccggaa
     1201 cagcgtttcc tcattcaacg gggcaaggat aaagatggtc agcaacgtca ggatcacgtc
     1261 aggtatggac ttatcggcaa aaagtttcgt cataaatggc tcagcaggca gagccagcgc
     1321 cttaccgagc agaaatacac cgacatacac cacggccatc gcaccgacca gccacggtac
     1381 gccaacgttg cgcagctgac caacgaccgg tagcggagct atccaacggc ggtataccag
     1441 gaaaacacac agcaggtaca tcagaacagt accatgactg aagaacaaat agttttttcc
     1501 tgatccataa agcagaacgg cctgctccat gacaaatctg gctccccaac taatgcccca
     1561 tgcagccagc ataaccagca taaactgcag atattgatta cgtgtttgaa tcattgcatc
     1621 gcctgtaaat ttttaacttg tcctattttt gtcattacca cgtatataca catgtataac
     1681 aattcagata tcgttaccag gatatgccgc atcagcggca tggaaggcgg cactctgttg
     1741 tttcatatga tacaggagta aaaccgccga agcccggcgt aagccggtac tgattgatag
     1801 atttcacctt acccatcccc agccctgcca gaccataccc gctttcagcc atgagagagc
     1861 ttctgtgcgc ggtcggagtg gtcccgacga gggtttaccc gaagtcgggg cgtatctccg
     1921 cgttagcggg ccgtgagggc cgcttacgag cgtgtactga gaacttccag cgagaagact
     1981 gacagcgatg aagatgtagt tacaacattc ataattaaaa gcgactctgt tccggccctt
     2041 tgggccgggg cggggccgct tttcagttat gagggagggg ctttgtggtt tcggttctgc
     2101 gctggaccgg ggtttttctg gaggttgttt ttgtgtgttg taactaaagt ggctccggtc
     2161 ggggcccgcc gcttgcggtg ggaggtgcat atctgtctgt ccacaggaca ggcagtgaat
     2221 aggttttctt tttaaatgaa tgtaattaag tagtttaaag gagatataaa caggtgttta
     2281 aaagatacat tgcaccctgt aagactggcg gctggcgctt tatgacatga acggttgtaa
     2341 ccttatgggg aagtcccttg cagt
//
LOCUS       DACAOP010000226         2325 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.228, whole genome shotgun sequence.
ACCESSION   DACAOP010000226 DACAOP010000000
VERSION     DACAOP010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2325
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.228"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..1317)
                     /locus_tag="IT892_004573"
     CDS             complement(<1..1317)
                     /locus_tag="IT892_004573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase-like activity of phytase family
                     protein"
                     /protein_id="HAP3137682.1"
                     /translation="MKRKIIPVLIGCTLSFSALAAQPTAERYVVSFPEGTHVNYAGAF
                     ASAFPNGLPVGIGSGLLFTGKQGDALTFATITDRGPNADSPKEGKNETKIFVTPDFAP
                     LLMTIRVQNGKAEAIDPRPLHDDKGAINGLPLASDVIGSTNEVAFSDTLHRLKGDNRG
                     LDTEGITPDGKGGYWLCDEYGPFLINIDSKGKILAIHGPQAAEEEKAIAGGLPNILKW
                     RQANRGFEGLTRMPDGRIIVAVQSTLDIDAKSKKKALFTRLVSFDPASGKTAMYGYPI
                     DSAAYSKNSDAKIGDIVALDNQHILLIEQGRDKNNRMRNLIYEVDLNKASDLSGFDKP
                     GEYPEFDDEKTLSQRGITLAQKTQVVDLRSLGWQQEKAEGLALIDSKTLAVANDNDFG
                     VKVAMQHPVEGKTFKDYRVNAEGKLTLDDKQVETTLRVKPLEKPESD"
     gene            1599..1730
                     /locus_tag="IT892_004574"
                     /pseudo
     CDS             1599..1730
                     /locus_tag="IT892_004574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1696..1905
                     /locus_tag="IT892_004575"
     CDS             1696..1905
                     /locus_tag="IT892_004575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000937735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137683.1"
                     /translation="MLPSETMIWQPEFTDKTLSRKPGAVHLAACPLLLDKIITIHRVK
                     QVVTASLKLRDYDGQVAEAMPMIPK"
     gene            complement(2068..2325)
                     /locus_tag="IT892_004576"
     CDS             complement(2068..2325)
                     /locus_tag="IT892_004576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm development YmgB/AriR family protein"
                     /protein_id="HAP3137684.1"
                     /translation="MHSDYYNMVFGEKLANILYEANSQFFYERNVIEEAVNALFCERE
                     IINNKNIIKKLMFFLSDVNHTKKDVVQSALNIIIDITSGDI"
BASE COUNT          571 a          583 c          544 g          627 t
ORIGIN      
        1 gtcagactcc ggtttctcca gtggcttcac tctgagggtc gtttcaacct gcttgtcgtc
       61 aagcgtcagc tttccttccg cgttcacccg ataatccttg aatgtcttgc cctcgaccgg
      121 atgttgcatc gccaccttca cgccaaagtc gttatcgttc gccaccgcca gcgttttgct
      181 gtcgatcagc gccaatcctt cagccttctc ctgctgccag cccaaggagc gcagatcaac
      241 aacctgcgtt ttctgcgcaa gggtaatgcc gcgctgtgac agggttttct catcatcaaa
      301 ctccggatac tcacccggct tgtcgaagcc tgacaggtcg ctcgccttat tgagatcgac
      361 ctcgtaaatc aggttacgca ttctgttgtt tttatctctt ccctgttcga tcagcaggat
      421 gtgctggtta tcgagcgcca cgatgtctcc gattttagcg tcgctgtttt tgctgtaggc
      481 cgcgctgtcg atgggataac cgtacatcgc ggtttttccg cttgccggat cgaagctcac
      541 cagacgcgta aacagcgcct ttttcttgct cttagcgtcg atatccagcg tactttgcac
      601 ggcgacaata atacgcccgt ccggcatacg ggtgaggcct tcaaagccgc ggttcgcctg
      661 acgccatttg aggatatttg gcaaaccgcc cgcaatcgct ttttcctctt ccgccgcctg
      721 cggaccgtgg attgccagga ttttcccttt actgtcgatg ttaatcagga acgggccata
      781 ctcatcgcac agccagtaac ctcctttacc atccggagtg atcccttccg tatccagccc
      841 gcgattatcc cccttcagtc tatgtaacgt gtcgctgaag gccacttcat tggtggagcc
      901 aatcacgtcg cttgccagcg gcagaccgtt gatcgcgcct ttatcgtcat gcagaggacg
      961 gggatcgatg gcctccgctt tgccgttttg tacacgaatc gtcatcagca gcggcgcgaa
     1021 atctggcgta acgaaaattt tagtttcgtt tttcccctct ttcggtgaat ccgcgttcgg
     1081 accgcgatcg gtaatggttg cgaatgtcag ggcatcgccc tgtttaccgg tgaacagcag
     1141 gccagaacct atcccaaccg gaaggccgtt cgggaatgca ctggcaaatg cgccggcgta
     1201 gttcacgtgc gtgccttctg gaaaactgac gacatagcgc tcagccgtag gttgtgccgc
     1261 cagggcagag aaagagagcg tacaaccgat tagcacggga ataatttttc ttttcatatt
     1321 gttagcatcc ataaagtgaa gatcacacta caccataaag aagaaacgag tcaggaaaat
     1381 gacatcgaat ggcaacatgc gcgggcctga ggccaaagaa atgtaaaaca ctgttgttat
     1441 ttgtaacaac ggaaacattt acggaaatta tttgtctttc ttcgtgatca aaaatgctgt
     1501 gtcttgttgg attggagtga tgagggctgc gtttaggaaa cgccctatat tgtacggttg
     1561 cattatcgcg gtaggggtaa tgcacgtgtc agtatgatga gctgaccaca ctcacgtggg
     1621 tggactggta taacaatcga cgattgctgg aaaggcaggg ccatatccca ccggcagaag
     1681 cagaaaaagc ttattatgct tccatcggaa acgatgatct ggcagcctga gttcacagat
     1741 aaaacactct ccaggaaacc cggggcggtt cacttagccg cgtgtccatt attgctggat
     1801 aagatcataa cgatacaccg ggttaaacag gtggtcactg cttcactgaa gctgcgtgat
     1861 tatgatggtc aggtagcaga agctatgccc atgataccaa aatgacgaaa gccgaaatgt
     1921 ctgaaagcgt gtgtattacc tgaaaatatg accggctccg gggtacgtaa ccgattcaac
     1981 aaagccaatc gatattacaa aacgagaggg actatatatt tcgttttcag ataagactcc
     2041 ttgagagatt atcttttatg taaaatctca aatatcacct gatgtaatgt caatgataat
     2101 attaagtgcg ctctgaacaa catctttctt ggtgtgatta acatctgaca aaaagaacat
     2161 cagcttcttt attatgttct tgttgtttat tatttcacgc tcacagaata aagcgttgac
     2221 tgcctcttct atgacatttc tctcgtaaaa aaattgagag ttagcttcat ataaaatatt
     2281 ggccaatttt tcaccaaaaa ccatattata ataatcactg tgcat
//
LOCUS       DACAOP010000227         2184 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.230, whole genome shotgun sequence.
ACCESSION   DACAOP010000227 DACAOP010000000
VERSION     DACAOP010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2184
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.230"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..1798
                     /locus_tag="IT892_004577"
     CDS             <1..1798
                     /locus_tag="IT892_004577"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase"
                     /protein_id="HAP3137685.1"
                     /translation="GKGWARLFGDNPGNIYVENMVIPEKKLNENNKAIVTVINDSEYT
                     VSIDDSTYHGKVGVQIKEPNISLLINKIDAQPGESFKIKYKTRLEAINDLANSFHVED
                     QGKDTGMLALTLIGDDPSLISVILNKISENYLEQNVSRQAAQDARSLEFLNERLPKVR
                     DDLDRAEDKLNSYRKQKDSVDLSLEAKATLDQLVNVDNQINELTFREAEISQLFTKDH
                     PTYKALIEKKNTLSKERGLLNNRISAMPATQQEVLRLSRDVESGRTVYMMLLNRQQEL
                     EISKSSAIGNVRIVDESVTEPEPVKPKKAMVIILGVLLGGLISVGVVLLRVSFRRGIE
                     SPEQLEEVGISVYSSIPLSEWLESNKKTKHGDSRNLLAIDNPADLAIEAIRGLRTSLH
                     FAMLEAKNNILMISGASPNAGKTFVSSNLAVIEAQTGKSVLFIDADMRKGYSHKLFGI
                     NIGNDNVGLSELLSSNYDFEKAINKIAEMKIDFISRGQVPHNPAEMLTSMKFDNLLRW
                     AASNYDLVIVDTPPVLAVTDAEIIGRYVGTTLLVARYETNTVKEMEVSIKRFERSGIN
                     VKGCILNGVMKKSSSYYGYGYNHYGYTYNDDK"
     gene            1852..>2184
                     /locus_tag="IT892_004578"
     CDS             1852..>2184
                     /locus_tag="IT892_004578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HAP3137686.1"
                     /translation="MFKILRVIPSMDPQKGGPSEGIRQLQQEIHRQRLNIKCDIVCMD
                     NLSEEAKDVEYASIYAVGKGKGVYSYSESLKNWLEENVRKYDFVIIHGIWQYHSYIAS
                     KLCIKNSIP"
BASE COUNT          774 a          303 c          460 g          647 t
ORIGIN      
        1 tggtaaaggc tgggctagat tatttggcga taatcccggt aatatttatg ttgagaatat
       61 ggttatacct gagaaaaagc ttaatgagaa taacaaagca atagtaactg tcattaatga
      121 tagcgaatat actgtatcta ttgacgattc tacttatcat ggaaaggttg gtgttcaaat
      181 aaaagagcca aatatatcat tgttaataaa taaaattgat gctcaacctg gtgaaagttt
      241 caagattaaa tataagacta gattagaggc aataaatgat ttagcgaatt cttttcatgt
      301 tgaagatcaa ggaaaagata ctggcatgtt agccttaact ttgattggag atgacccatc
      361 attaatttca gtgatactca ataaaataag cgaaaattat ttggagcaaa atgtctctag
      421 gcaagctgca caagatgcaa ggagtctcga gtttctaaat gaacgcttgc caaaagtaag
      481 agatgatctg gatagagcag aagataagct caatagttat agaaaacaga aagattcggt
      541 cgatttgtca ttagaagcta aagccacatt agatcaacta gttaatgttg ataatcaaat
      601 taatgaactg acctttcgag aggctgaaat atcgcagctt tttactaagg atcatccgac
      661 ttataaagca cttatcgaga agaaaaatac attaagtaaa gagcgtggtt tgttgaataa
      721 tagaatttct gcgatgccag caactcagca agaagtctta cgtctgagtc gtgatgtcga
      781 atctggacgt actgtttata tgatgctatt aaacagacag caagagctgg aaatttctaa
      841 atcaagtgca attggtaatg ttcgtattgt tgatgagtcc gttactgagc cagagccagt
      901 aaaacccaaa aaagcaatgg ttattatatt aggagttctt ctcggtggct taatctctgt
      961 tggtgtcgtt ttactaagag tatcatttag aagaggaatt gaatcgcccg aacagctaga
     1021 agaagtaggg attagcgttt attcaagcat tcctttatca gaatggttag aaagtaataa
     1081 aaaaacaaag catggtgata gcagaaatct gcttgctata gataatccag ctgacttagc
     1141 catagaggcg attaggggct taagaacaag cctccatttt gctatgcttg aagccaaaaa
     1201 taatatatta atgatatcgg gtgctagccc taatgctggt aaaacatttg ttagcagtaa
     1261 tttggcagta attgaagctc aaaccggtaa gtctgtatta tttattgatg ccgatatgag
     1321 aaaggggtac tctcataaat tatttggcat aaacattggc aatgataatg ttggattgtc
     1381 ggaattgctt tcaagtaatt atgattttga aaaagcaatt aataagatag cagaaatgaa
     1441 aatagacttc atttctagag gtcaagtacc acataatccg gctgaaatgt taacaagcat
     1501 gaaatttgat aatttattac gatgggccgc aagcaattat gacttggtta ttgttgatac
     1561 accgccagtc ctagcagtga cagatgctga gattattggt cgctatgttg gaacaacttt
     1621 gttggttgct cgatatgaaa caaacacggt taaagaaatg gaagtcagta taaaacgttt
     1681 tgagcgaagc ggtattaatg ttaaaggttg catactcaat ggcgtaatga aaaaatctag
     1741 ctcgtattat ggctatgggt ataatcatta tggatataca tataatgatg ataaataata
     1801 cttattctaa tttcgaatca aaaaaattaa gtttatcata aggggggggc aatgtttaaa
     1861 attcttcgag tcattccttc aatggatccg caaaagggag gtccatctga aggtatcaga
     1921 cagcttcagc aagagataca taggcaacga ttaaatataa agtgcgatat agtatgcatg
     1981 gataatttat cagaagaagc caaagatgtt gagtatgcta gtatttatgc ggtgggtaaa
     2041 ggtaaaggtg tatattcata ttcagaaagc ttgaaaaatt ggctagagga aaatgtaaga
     2101 aaatatgatt ttgtaataat tcatggtatc tggcaatatc atagctatat tgctagcaaa
     2161 ttatgtatta aaaacagcat cccg
//
LOCUS       DACAOP010000228         2131 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.231, whole genome shotgun sequence.
ACCESSION   DACAOP010000228 DACAOP010000000
VERSION     DACAOP010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2131
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.231"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>2131
                     /locus_tag="IT892_004579"
     CDS             <1..>2131
                     /locus_tag="IT892_004579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HAP3137687.1"
                     /translation="ALPPDIRLSPHLYLATNSAQGPWWILGWSERVPGAEDVLPAPLP
                     PYRVLTGMADRFGRTLTYRREAAGDLAGEITGVTDGAGREFRLVLTTQAQRAEEARTS
                     SLSSSDSSRPLSASAFPDTLPGTEYGPDRGIRLSAVWLMHDPAYPESLPAAPLVRYTY
                     TEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPA
                     GLSYRYLYEQDRITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTRSGYDAAGRLT
                     AQTDAAGRRTEYGLNVVSGDITDITTPDGRETKFYYNDGNQLTAVVSPDGLESRREYD
                     EPGRLVSETSRSGETVRYRYDDAHSELPATTTDATGSTRQMTWSRYGQLLAFTDCSGY
                     QTRYEYDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGRETRYEYNAAGDLTAVI
                     TPDGNRSETQYDAWGKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRL
                     VQQGGFDGRTQRYHYDLTGKLTQSEDEGLVILWYYDESDRITHRTVNGEPAEQWQYDG
                     HGWLTDISHLSEGHRVAVHYGYDDKGRLTGECQTVENPETGELLWQHETKHAYNEQGL
                     ANRVTPDSLPPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETVRSFGSMAGSNAAY
                     ELTSTYTPAGQLQSQHLNSLVYDRDYGW"
BASE COUNT          454 a          623 c          735 g          319 t
ORIGIN      
        1 gcgctgccgc cggatatccg gttaagcccg catctttacc tggcgaccaa cagcgcacag
       61 gggccgtggt ggatactggg gtggtctgag cgggtgccgg gtgctgagga cgtactgcca
      121 gcgccgctgc cgccgtaccg ggtgcttacc gggatggcgg accgcttcgg gcggacgctg
      181 acgtaccggc gtgaggccgc cggtgacctg gccggggaaa tcaccggcgt gacggacggt
      241 gccgggcggg agttccgtct ggtgctgacc acgcaggcgc agcgtgcgga agaggcccgc
      301 acctcttcgc tatcttcttc tgacagttcc cgccctctct cagcctcagc gttccccgac
      361 acactgcccg gtaccgaata cggccccgac aggggtatcc gcctttcggc ggtgtggctg
      421 atgcacgacc cggcataccc ggagagcctg cccgctgcgc cactggtgcg gtacacgtat
      481 acggaagccg gtgaactgct ggcggtatat gaccgcagca atacgcaggt gcgcgctttc
      541 acgtatgacg cgcagcaccc gggccggatg gtggcgcacc gttacgcggg aaggccggag
      601 atgcgctacc gctacgacga tacggggcgg gtggtggagc aactgaaccc ggcagggtta
      661 agctaccgct atctttatga gcaggaccgc atcaccgtca ccgacagcct gaaccggcgt
      721 gaggtgctgc atacagaagg cggggccggg ctgaaacggg tggtgaaaaa agaactggcg
      781 gacggcagcg tcacgcgcag cgggtatgac gcggcaggaa ggctcacggc gcagacggac
      841 gcggcgggac ggaggacaga gtacggtctg aatgtggtgt ccggcgatat cacggacatc
      901 accacaccgg acgggcggga gacgaaattt tactataacg acgggaacca gctgacggcg
      961 gtggtgtccc cggacgggct ggagagccgc cgggaatatg atgaaccggg caggctggta
     1021 tcggagacat cgcgcagcgg ggagacagta cgctaccgct acgatgacgc gcacagtgag
     1081 ttaccggcga cgacaacgga tgcgacgggc agcacccggc agatgacctg gagccgctac
     1141 gggcagttgc tggcgttcac cgactgctcg ggctaccaga cccgttatga atacgaccgc
     1201 ttcggccaga tgacggcggt ccaccgcgag gaaggcatca gcctttaccg ccgctatgac
     1261 aaccgtggcc ggttaacctc ggtgaaagac gcacagggcc gtgaaacgcg gtatgaatac
     1321 aacgccgcag gcgacctgac tgccgttatc accccggacg gcaaccggag cgagacacag
     1381 tacgatgcgt ggggaaaggc ggtcagcacc acgcagggcg ggctgacgcg cagtatggag
     1441 tacgatgctg ccggacgtgt catcagcctg accaacgaga acggcagcca cagcgtcttc
     1501 agttacgatg cgctggaccg gctggtacag cagggcggct ttgacgggcg gacgcaacgt
     1561 tatcattatg acctgaccgg aaaactcaca cagagtgagg atgagggact tgtcatcctc
     1621 tggtactacg atgaatcgga ccgtatcact caccgcacgg tgaacggcga accggcagag
     1681 cagtggcagt atgatggcca cggctggctg acagacatca gccacctgag cgaaggccac
     1741 cgtgttgccg tccactatgg ctatgacgat aaaggccgcc tgaccggcga atgccagacg
     1801 gtggagaacc cggagacggg ggaactgctg tggcagcatg agacgaaaca cgcatacaac
     1861 gagcaggggc tggcaaaccg cgtcacgccg gacagcctgc cgccggtgga gtggctgacg
     1921 tatggcagcg gttacctggc gggaatgaag ctgggcggga cgccgctggt cgagtatacg
     1981 cgggacaggc tgcaccgtga gacggtgcgc agcttcggca gcatggcagg cagtaatgcc
     2041 gcatacgaac tgaccagcac atacaccccc gcaggccagt tacagagcca gcacctgaac
     2101 agcctggtat atgaccgtga ctacgggtgg a
//
LOCUS       DACAOP010000229         2125 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.232, whole genome shotgun sequence.
ACCESSION   DACAOP010000229 DACAOP010000000
VERSION     DACAOP010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2125
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.232"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            235..753
                     /locus_tag="IT892_004580"
     CDS             235..753
                     /locus_tag="IT892_004580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HAP3137688.1"
                     /translation="MPTPCYISITGQTQGNITAGAFTADSVGNIYVQGHEDEMLVQEF
                     LHNVTVPTDPQSGQPAGQRAHKPFIFTVALNKAVPLMYNALASGEMLPTTELHWWRTS
                     VEGKQEHYFTTRLTDSTIVDMKLHMPHCQDPAKREFTQLLEVSLAYRKIEWEHVKSGT
                     SGADDWRAPLEA"
     gene            963..>2125
                     /gene="tssI"
                     /locus_tag="IT892_004581"
     CDS             963..>2125
                     /gene="tssI"
                     /locus_tag="IT892_004581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HAP3137689.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQ
                     FLSLEFQQILDKMAYLTIWQGDDVQRRVKGVVTWFELGENDKNQKLYSMKVCPPLWRT
                     GLRQNFRIFQNEDIESILGTILQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAQKSTDQSLVLCDTVRYLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGWAGRFDQEGQYQDYQRTQYEVYDYPGRFKGAHGQNFARWQ
                     MDGWRNNAEVARGTSRSPEIWPGRRIVLTGHPQANLNREWQVVASELHGEQPQAVPGR
                     SGSGTTLNNHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRV"
BASE COUNT          506 a          549 c          593 g          477 t
ORIGIN      
        1 ggactttgaa cagttgggta tggttatcca gatatatatt attaagttat tgctgaataa
       61 gagatttaat gattttaaaa atagttttta cgacaaccgt aaattctagc tcggtttgta
      121 tgtaaaaaat actgaaaatg atgcggttcc gtgaagtgag ctgcatctgc ctgtctggga
      181 ttaacggcag gtcattgtaa gtagtaatta accacgttaa caaggagttt acaaatgcca
      241 acaccgtgtt atatctccat cactggtcag acccagggaa atattactgc aggtgcattt
      301 accgctgatt ctgtcggcaa catctatgtg caggggcacg aagacgagat gctggtgcag
      361 gaattcctgc ataacgttac tgtcccgacc gatcctcagt ccggtcagcc tgcgggtcag
      421 cgtgctcaca agcctttcat ttttaccgtg gcgctgaaca aagcggttcc gctgatgtac
      481 aacgcactgg cctccggcga aatgctgcca accactgaac ttcactggtg gcgtacctct
      541 gtggaaggca aacaggagca ttatttcact acccgcctga ctgattcgac gattgtcgat
      601 atgaaactgc atatgccgca ttgccaggac ccggcgaaac gcgagttcac ccagttgctc
      661 gaagtttcac tggcctaccg caaaattgaa tgggaacacg tcaaatctgg cacctccggt
      721 gccgacgact ggcgcgcacc gctggaagca taagttaagc caacagcatc cggctatcag
      781 gccggatgct gtttttgtat tacgccgtag aaagaaaggt tgtcagtaag gggttacgtt
      841 cacgggagat ggcggctgcc ggaaacttcg gcggtagcgt gcctgaacgc aagcgtaaca
      901 ctgtactgtc acagccgctt taacagcgaa ctgtctgttt ttccttaacc ccggaggttg
      961 ctatgtcaac cggattacgt ttcacgctgg aagtggacgg cctgccaccg gatgcttttg
     1021 cggtggtttc ctttcatctg aaccagtcac tctcttcgct tttttccctc gatctctctc
     1081 tggtcagcca gcagtttctc tcccttgaat tccagcagat cctcgacaaa atggcctacc
     1141 tgacgatatg gcagggcgat gacgtacagc gccgggtgaa aggtgtggtg acctggtttg
     1201 aactggggga gaacgacaaa aaccagaagc tgtacagcat gaaggtatgc ccgccgctgt
     1261 ggcgcacagg gctgcgccag aacttccgta tcttccagaa tgaggacatc gaaagcatcc
     1321 tcggcacgat attgcaggaa aacggggtga ccgagtggag cccgctgttc agcgagccac
     1381 atccttcccg tgagttttgt gtccagtacg gtgagactga ttacgatttc ctgtgccgga
     1441 tggcggcgga ggaaggcatc ttcttttatg aggagcacgc gcaaaaaagt accgaccaga
     1501 gcctggtcct gtgcgatacc gtgcgttatc tgccggagtc ctttgagatc ccctggaatc
     1561 cgaacacccg taccgaggta agcaccctct gcatcagcca gtttcgctac agcgcacaaa
     1621 tccgcccttc ttccgtggtg accaaagact acacctttaa acgacccggc tgggcagggc
     1681 gttttgatca ggaaggccag taccaggatt accagcgcac acagtatgaa gtgtatgact
     1741 accccggacg tttcaagggt gctcacgggc agaactttgc ccgctggcag atggatggct
     1801 ggcgcaacaa cgcagaagtg gcgcgcggaa caagccgttc tccggagata tggccgggac
     1861 ggcgaattgt gctgacgggg catccgcagg cgaacctgaa ccgggaatgg caggtggtgg
     1921 caagtgaact gcacggcgag cagccgcagg cggtgccggg acgcagtggt tcaggaacca
     1981 cgctgaataa ccactttgcg gtaataccgg cagaccggac atggcggcca cagccgttgc
     2041 tgaaaccgct ggtggacggc ccgcagagcg ccgtcgtgac gggaccggca ggcgaggaaa
     2101 tcttctgtga tgaacatggc cgcgt
//
LOCUS       DACAOP010000230         2035 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.234, whole genome shotgun sequence.
ACCESSION   DACAOP010000230 DACAOP010000000
VERSION     DACAOP010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2035
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.234"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..638
                     /locus_tag="IT892_004582"
     CDS             <1..638
                     /locus_tag="IT892_004582"
                     /inference="COORDINATES: protein motif:HMM:NF012744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP3137690.1"
                     /translation="LKHIKKMLYWTLIERKVVNNAEAVIFTSEEEKILARQSFPFYEP
                     KEFVTAYGTSGSIFDKEIARSEFYKKFPFLKGKKILLYMGRIHEKKGCDILIKSYAKI
                     SKEHNDYHLFIAGPDTSAYAKTLKDLVSSLNLNDKVTWGGMLSGDVKWGAYYSSEVFC
                     LASHQENFGIVVAEALSCEIPVVTTTKVNIWREIERADAGMIAIDNDDSFT"
     gene            861..2027
                     /locus_tag="IT892_004583"
     CDS             861..2027
                     /locus_tag="IT892_004583"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137691.1"
                     /translation="MFIAQTLLISKSEVALVGQITIGLGLLTLAQWLADAGGVFLIPR
                     LLGSEENEQKKLACFINARFIFVTIIVISVLVYLIAKNSWHLYYGLVSFIIPVLLISS
                     FSVLGYLDFYNETKASGTLSGVSWSLASLPLYYSYFYEGDRYIIGMSAGLLFVLGNAL
                     FIIIQCIKMKQVSKNGGVKLTYKDGFCIKQIKYSFYDIIKYNLNYGFSQSYGRFVPIF
                     LNTLLGPVLAGYYIYAKSFANIANQFIAFSRRVEFSNLIAIHDGSVRKILSSQLISFG
                     IACIFAMFCFGAELVECFYTLPIGNNTLLYIQIIALINLLWCLSSSFSQYFLAKGKLG
                     FICITQLITYILSLSIIYFGVDFLSIYSVFVAESIMYVVQFLIFIVFLKTYKKL"
BASE COUNT          648 a          273 c          388 g          726 t
ORIGIN      
        1 cattaaagca tatcaaaaaa atgctttatt ggacattaat tgagcgaaaa gtcgtgaaca
       61 atgcagaggc tgttatattt acaagtgaag aggaaaaaat actagcacgt cagtcattcc
      121 cattctatga accaaaagaa tttgtaactg catacggaac ttctggtagt attttcgata
      181 aagagattgc aaggagtgaa ttttataaaa aattcccttt tctaaaaggt aaaaaaatac
      241 ttctttatat ggggcgaatt catgaaaaaa agggatgtga tatattaata aaatcatatg
      301 caaaaatcag taaagagcat aatgactatc atttgtttat tgctgggccg gatacgtctg
      361 catacgcaaa aacgttgaaa gatcttgtgt cctctttaaa tttaaatgac aaagtaactt
      421 gggggggaat gcttagtggt gatgtaaaat ggggcgctta ttattcaagt gaggtttttt
      481 gcttagcatc acaccaagaa aactttggga tagttgttgc agaagcctta tcatgtgaga
      541 ttcctgttgt tactactacg aaagtcaata tctggcgaga aatagaacgc gctgatgctg
      601 gcatgattgc aatagataat gatgattctt ttacttaaat actaaatgag tttcttaaaa
      661 aatacgaaaa cgatcgtgag agattaagag ggaatgcctt gagatgcttt aaggaaaact
      721 ttgacataaa acttgtagcg acatcattta acaacttaat atcctctgaa cgataagata
      781 ttaaccctta taggagaggg acgttgagat atcgaagttt ttataactta gttttcggat
      841 ttcttattgg gcaaggagca atgtttatag cgcaaacatt gttaatttct aaatctgaag
      901 ttgcacttgt tggccaaatt acaattggtc taggactatt gacattagct cagtggttgg
      961 ctgatgctgg aggggtgttt ttaataccgc gtttgttagg ctcagaagaa aatgaacaaa
     1021 aaaaattagc gtgctttatt aatgcgagat ttatttttgt cacaattatt gttataagtg
     1081 ttctagttta tcttattgct aaaaattcgt ggcatctata ctacggactc gtatcattta
     1141 taattcctgt tttgctgata tcatccttta gtgtacttgg ttatctcgat ttttataatg
     1201 aaacgaaggc ttctggaaca ttgtctggag tgtcttggtc attagcctca ttgcctttgt
     1261 attattcata tttctatgaa ggagatagat atatcatagg tatgagtgct gggctgcttt
     1321 ttgttttagg gaacgcatta tttataataa ttcaatgcat taaaatgaaa caagtaagca
     1381 agaatggcgg ggttaaattg acatataagg atggtttttg cataaaacag ataaaatatt
     1441 cattttatga tatcattaaa tataatttga actatgggtt ttcgcaaagt tatggaagat
     1501 tcgtcccgat tttcttaaat acacttttag gccctgttct ggctgggtat tacatatatg
     1561 ctaaaagttt cgcaaacatt gcaaatcaat ttatagcttt ctccagaaga gttgagttta
     1621 gtaatctgat cgcaattcat gatggaagtg ttaggaaaat attatccagt cagttaatta
     1681 gctttggcat tgcatgtata tttgcgatgt tttgttttgg agctgaactt gtagagtgtt
     1741 tttacacatt accaattgga aataatactc tattatatat acaaattata gcattaatta
     1801 atctgctatg gtgtttgtca agctcatttt cccagtattt ccttgccaaa gggaagttgg
     1861 gctttatctg tattacgcaa ttaattactt atattttatc tttgtcaatt atttattttg
     1921 gcgttgattt tttatcaatt tattcagtct ttgttgctga atcaataatg tatgttgttc
     1981 aattcttaat ttttatagtg tttttgaaaa cttataaaaa gttataatta tcaat
//
LOCUS       DACAOP010000231         1991 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.235, whole genome shotgun sequence.
ACCESSION   DACAOP010000231 DACAOP010000000
VERSION     DACAOP010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1991
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.235"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(189..1235)
                     /locus_tag="IT892_004584"
                     /pseudo
     CDS             complement(189..1235)
                     /locus_tag="IT892_004584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513488.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
     gene            1217..1324
                     /locus_tag="IT892_004585"
                     /pseudo
     CDS             1217..1324
                     /locus_tag="IT892_004585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
     gene            1421..>1991
                     /locus_tag="IT892_004586"
     CDS             1421..>1991
                     /locus_tag="IT892_004586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISEc9 family transposase"
                     /protein_id="HAP3137692.1"
                     /translation="MINKIDFKAKNLTSNAGLFLLLENAKSNGIFDFIENDLVFDNDS
                     TNKIKMNHIKTMLCGHFIGIDKLERLKLLQNDPLVNEFDISVKEPETVSRFLGNFNFK
                     TTQMFRDINFKVFKKLLTKSKLTSITIDIDSSVINVEGHQEGASKGYNPKKLGNRCYN
                     IQFAFCDELKAYVTGFVRSGNTYTANGAAE"
BASE COUNT          561 a          440 c          412 g          578 t
ORIGIN      
        1 ggggaaccgc agaattcgga aaaaatcgta cgctaagcta acggtgttct cgtgacagct
       61 ctttgactag gctttctaag gccattctga tagccctgac ttcctgaaaa gccatggcta
      121 aaatttgtgc ggctaaaagg gataaccgat ggtaaagtaa gttatccctg tcgagatact
      181 gaaaagcgtt atcctcgttt ttcccaaaac tgttttgcca gttcgctcag agcgctagtt
      241 aactgagcga cagatttcgc actttgcaaa ttattctgcc cggtctgtac attggtatca
      301 gcagcatcgc gtatattgat aatactgcgg tttatgtctt cacttactgc tccctgctgc
      361 tcgaccgcag tcgctatttg cgcgttcatg tcggtaattt cgttaacgcg ttggccaatt
      421 ccatcaagag ctgtagctgc ttcctctgcg tgagctacac tcgtgtgcgc ttgccgacta
      481 ctttgctcca tgactgtaac agcggattgc gctcgctctt gtagagcgct gatcatgctt
      541 tgaatatccg ttgtcgattg ctgtgtgcga gcagcaagac tgcgaacctc atcggcgaca
      601 acagcaaaac cacgcccctg ctcaccagca cgcgcggcct caattgctgc gttgagtgcc
      661 aacaaattcg tttgctcggc gatccctcgt ataacgtcaa gaacttttga tatctcgtta
      721 ctttgacctt caagctcatg aataacctga gtggcttgcc taatttcacc ttcaagggca
      781 gtgattgact ggcttgtgtg ggctaccaga cgctggccag atgccgtctc agtgtctgct
      841 cttccggccg catctgcagc atgctgtgca ttgctcgcaa cctcttgaat gcttgccacc
      901 atttggttta ctgccgttgc tatttgatct gtctctgcct gctgctcaac tgtaagtaca
      961 ttgcttgact caatatcctt tagtaggcct cgggtgtgtt cgctaagccg atttgatgca
     1021 tcacctatgc gacctactat ggcgcctgtt tcagcttgca tcattcgtaa agcaaactct
     1081 atttggccaa actcatcggt gcgcccagtg tagagggatt gacttaatgg gttattggaa
     1141 atattcctgg ctctttcaac cagtcttcca agaggagaga gaatagccaa aacactaaca
     1201 gagcttaagc ttcctgacat taaagtggct aacacctaga ttctacgtca gtacttcaaa
     1261 aagcataatc aaagccttga taaatatgca ttccttcgaa attcagcttt cacccattgg
     1321 gtgaaagaaa agtgctcaaa aatatgttaa attatcagct tttatgactc gatatatggt
     1381 aaaataatag taagaaaagt agtaaaaagg ggttctaatt atgattaata aaattgattt
     1441 caaagctaag aatctaacat caaatgcagg tctttttctg ctccttgaga atgcaaaaag
     1501 caatgggatt tttgatttta ttgaaaatga cctcgtattt gataatgact caacaaataa
     1561 aatcaagatg aatcatataa agaccatgct ctgcggtcac ttcattggca ttgataagtt
     1621 agaacgtcta aagctacttc aaaatgatcc cctcgtcaac gagtttgata tttccgtaaa
     1681 agaacctgaa acagtgtcac ggtttctagg aaacttcaac ttcaagacaa cccaaatgtt
     1741 tagagacatt aattttaaag tctttaaaaa actgctcact aaaagtaaat tgacatccat
     1801 tacgattgat attgatagta gtgtaattaa cgtagaaggt catcaagaag gtgcgtcaaa
     1861 aggatataat cctaagaaac tgggaaaccg atgctacaat atccaatttg cattttgcga
     1921 cgaattaaaa gcatatgtta ccggatttgt aagaagtggc aatacttaca ctgcaaacgg
     1981 tgctgcggaa a
//
LOCUS       DACAOP010000232         1979 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.236, whole genome shotgun sequence.
ACCESSION   DACAOP010000232 DACAOP010000000
VERSION     DACAOP010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.236"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..1120)
                     /gene="tssI"
                     /locus_tag="IT892_004587"
     CDS             complement(<1..1120)
                     /gene="tssI"
                     /locus_tag="IT892_004587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HAP3137693.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQ
                     FLSLEFAQVLDKMAYLTIWQGDEVQRRVKGVVTWFELGENDKNQMLYSMKVHPPLWRA
                     GLRQNFRIFQNEDIKSILGTMLQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAYKSTDQSLVLCDTVRHLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGWAGRFEQEGQHQDYQRTQYEVYDYPGRFKGAHGQNFARWQ
                     MDGWRNNAETARGMSRSPEIWPGRRIVLTGHPQANLNREWQVVASELHGEQPQAVPGR
                     QGAGTALENHFAVIPADRTWRPQPLLKPLVDGPQSAVVT"
BASE COUNT          501 a          508 c          461 g          509 t
ORIGIN      
        1 ccgtcacgac ggcgctctgc gggccgtcga ccagcggttt cagcaacggc tgtggtcgcc
       61 atgttctgtc tgccgggatc accgcaaaat ggttctccag cgccgtcccc gctccctgcc
      121 gtcctggcac cgcctgtggc tgttcgccgt gcagttcact tgccaccacc tgccattccc
      181 ggttcaggtt cgcctgcgga tgccccgtca gcacaattcg tcgtcccggc catatctccg
      241 gcgagcgact cattccccgc gcggtttctg cattgtttcg ccagccgtcc atctgccagc
      301 gggcaaagtt ctgcccgtgg gcacccttga aacgtccggg gtagtcatac acttcatact
      361 gcgtgcgctg gtagtcctgg tgctggcctt cctgttcaaa acgtccggcc cagccggggc
      421 gtttaaaggt gtagtctttg gtcaccacgg aagaagggcg gatttgtgcg ctgtagcgga
      481 actggctgat gcagagggtg ctcacctcgg tacgggtgtt cgggttccat gggatttcaa
      541 aagattcggg cagatggcgg actgtgtcgc acagcaccag gctctggtcg gtacttttgt
      601 aagcatgctc ctcataaaag aagatgcctt cctccgccgc catccggcac aggaaatcgt
      661 aatcagtctc accgtactgg acacaaaact cacgggaagg atgcggctcg ctgaacagcg
      721 gactccattc ggtcaccccg ttttcctgca acatcgtgcc gaggatgctt ttgatgtcct
      781 cgttctggaa gatacggaag ttctggcgca gaccggcacg ccacagcggc gggtgcacct
      841 tcatgctgta cagcatctgg tttttgtcgt tctccccgag ttcaaaccag gtcaccacgc
      901 ctttcacccg gcgctgtact tcatcgccct gccatatcgt caggtaggcc attttgtcca
      961 gcacctgcgc aaattcaagg gagagaaact gctggctgac cagggagaga tcgagggaaa
     1021 agagcgaaga gagtgactgg ttcagatgaa aggaaaccac cgcaaaagca tccggcggca
     1081 ggccgtccac ttccagtgtg aaacgtaatc cggttgacat agcaacctcc gtgaaaatga
     1141 ataataatcc gcacatattg catgtacaac atgtcgggcg gatgagataa gcgagtcgac
     1201 atctggcgtt accggggaat atcagaaaaa tgtcatggtt atgtgatgat ttagtctggg
     1261 attttacttc agagaaacgg gtgtctgttt agtcaacaaa ataatcacaa acgcaacgga
     1321 tgggttctcg acgttattca cgacaggctc gtacattaca gcgagtaata aaaaacctga
     1381 tatgcaaagt caaaccaata ttcataatgt ctttttattc acaacaataa ataattcaat
     1441 aacaatcatt gaaatgaatg atggtttgta taaggaatat acgctaccgc cccaccctga
     1501 taacatgatc tgcacattgc catcttaacg tcgttaaaca ctagcttaat agtggatatt
     1561 tcaaattagg aatttattaa attcacctga tgaatataat aagcaaatag catagaaaat
     1621 aatgacaact cccccgaggg gaccatttcc aaagcactgc accaccacct ggtgccggat
     1681 gatcttgctt cagtggtaag agtacctgat gcattgttcc caaaatggtg ttttcccctg
     1741 cccctccaat aatgtgtagc tctcacttga taatctattg attaggttat attaagaatc
     1801 aacatttaaa atacatccat tttcttgaat aaatcaacat gtttattaat caattgctgt
     1861 tttagctctg actcatcaag ctctccatat ttgtcctaca gataattgcg aataaataca
     1921 gagaacgcca tttatccttt tagcatacct gccggatatt tttatttgta ttaatatta
//
LOCUS       DACAOP010000233         1978 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.237, whole genome shotgun sequence.
ACCESSION   DACAOP010000233 DACAOP010000000
VERSION     DACAOP010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1978
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.237"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..257
                     /locus_tag="IT892_004588"
     CDS             <1..257
                     /locus_tag="IT892_004588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137694.1"
                     /translation="LRQRELKLYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAALQE
                     KIAVTPQLTFNGAKILELDGRHPADEILQASQRAIHAALS"
     gene            289..1047
                     /locus_tag="IT892_004589"
     CDS             289..1047
                     /locus_tag="IT892_004589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137695.1"
                     /translation="MDALQTQTVNSTTAPQPNYIPGLIAVVGCDGTGKSTLTTDLVKS
                     LQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLAAKSSKTQSMKTKSPALWAAV
                     IMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFYYDGPGIGVERATGKISMF
                     LAQRERRLYQQMAQYRPELIIRLGIDIETAISRKPDHDYAELQDKIGVMSKIGYNGTK
                     ILEIDSRAPYSEVLEQAQKAVSLVAIVSDRRSLT"
     gene            1093..>1978
                     /locus_tag="IT892_004590"
     CDS             1093..>1978
                     /locus_tag="IT892_004590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HAP3137696.1"
                     /translation="MAGFNIKHWFADGAFRTIIRNSAWLGSSNVVSALLGLLALSCAG
                     KGMTPAMFGVLVIVQSYAKSISDFIKFQTWQLVVQYGTPALTNNNPQQFRNVVSFSFS
                     LDIVSGAVAIVGGIALLPFLSHSLGLDDQSFWLAALYCTLIPSMASSTPTGILRAVDR
                     FDLIAVQQATKPFLRAAGSVVAWYFDFGFAGFVIAWYVSNLVGGTMYWWFAARELRRR
                     NIHNAFKLNLFESARHIKGAWSFVWSTNIAHSIWSARNSCSTVLVGIVLGPAAAGLFK
                     IAMTFFDAAGTPAGLLGKS"
BASE COUNT          447 a          501 c          537 g          493 t
ORIGIN      
        1 tgttaaggca gcgcgagctg aagctgtacc aatggatggc atcttatttg cccgtattgt
       61 tgattcgtct tggcattgat gaacaaaccg cgtttgcgcg taaacctgac caccaactgg
      121 cagcgttaca ggaaaaaatc gccgttacgc cgcaactgac attcaatggc gcaaagatcc
      181 ttgaactgga tgggcgacac cccgccgatg aaattctgca agcgtcacaa cgcgcaattc
      241 acgccgcgct ttcctgatca ccaaaatgga taggggatga tttaacgaat ggatgcacta
      301 caaactcaaa ctgttaatag tacaaccgcg ccgcagccca actacattcc ggggctgatt
      361 gcggtggtcg ggtgtgatgg caccggtaaa tccacactga ccaccgacct ggtgaaatcg
      421 ctgcaacaac actggcaaac cgagcggcgc tatctggggc tgctctccgg cgaagacggc
      481 gacaaaatca aacgattgcc gttggttggc gtctggctgg aacggcgact ggcggccaaa
      541 tcctcgaaaa cccaaagcat gaaaaccaaa tctccggcgc tatgggcggc ggtgattatg
      601 tactgcttct cgctgcgaag aatggcgaat ctacgcaagg ttcagcgact ggcgcaaagt
      661 ggcgttctgg tggtcagcga tcgcttcccg caggctgaaa tttcgggctt ttattatgat
      721 ggaccgggga ttggcgtcga acgtgcgacc gggaaaatca gcatgtttct ggcgcagcgc
      781 gaacggcgtt tataccaaca aatggcgcaa tatcgcccgg aattaattat tcgcctgggc
      841 attgatattg agactgccat ctcccgcaag cctgaccatg actatgccga gctgcaggac
      901 aaaatcggtg tcatgtcgaa gattggctat aacggcacaa aaattcttga gattgattcc
      961 agagcgccct acagcgaagt gctggaacag gcacagaagg cggtttctct ggttgccatc
     1021 gtttctgacc gccgaagttt aacttaaggc tggcgggata ctttttacta tcaacgataa
     1081 ggtcaggctg aattggcggg ttttaacatc aaacattggt ttgcagatgg cgcgtttcgc
     1141 accattattc gcaatagcgc ctggttaggc tccagtaatg tcgtgagcgc cttgctgggt
     1201 ctgttggcgc tctcgtgtgc cggtaaaggg atgacgcccg ccatgtttgg cgtactggtg
     1261 attgtgcaat cgtacgccaa gtcgatcagc gattttatta agtttcagac atggcaactg
     1321 gtggttcagt acggaacacc agcattaacc aacaataatc cgcagcaatt ccgcaatgtc
     1381 gtctcatttt ccttctcgct ggatatcgtc agcggcgcgg tggcgattgt cggtggcatt
     1441 gccttactgc cattcctttc ccattcatta ggtctggatg accaaagttt ttggctggca
     1501 gcgctctatt gcacgctcat tccttcaatg gcttcctcca cgccgaccgg cattctgcgt
     1561 gcggtagatc gcttcgattt aattgctgta cagcaggcga cgaaaccttt tctgcgcgca
     1621 gcggggagcg tcgtagcctg gtattttgac tttggttttg cgggttttgt tattgcctgg
     1681 tacgtgtcga atctggttgg cggcaccatg tactggtggt ttgccgcgcg cgaattacgc
     1741 cgccgaaata tccataacgc cttcaaattg aatctgtttg agtctgcccg acacattaaa
     1801 ggcgcgtgga gttttgtctg gtcaaccaac attgcccact ccatctggtc ggcgcgtaac
     1861 tcgtgcagca cagtgttggt ggggatcgtg ttaggacccg ctgccgccgg gttatttaaa
     1921 atcgccatga cattcttcga cgccgccgga acgccagcgg gtttgctggg taaaagtt
//
LOCUS       DACAOP010000234         1962 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.238, whole genome shotgun sequence.
ACCESSION   DACAOP010000234 DACAOP010000000
VERSION     DACAOP010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1962
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.238"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            566..823
                     /locus_tag="IT892_004591"
     CDS             566..823
                     /locus_tag="IT892_004591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001333498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP3137697.1"
                     /translation="MEMEKQDWHKADIIAALHKKGLSLASLSRANGLSSSTLANALTR
                     DWPRGEIIIANAIGEEPQEIWPTRYFDKAGMPIKRIIRKPV"
     gene            994..1485
                     /locus_tag="IT892_004592"
     CDS             994..1485
                     /locus_tag="IT892_004592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000217395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP3137698.1"
                     /translation="MTVLSAPEMRFGTKQDVPFIIAVIRDGMRDGYFNFDDDDGLSQF
                     ESQISEAIARRERGENCADFLFVFDAQHNGAAIGFALLTGKNGANGLASHLEIRMFGV
                     TRSQRQKGFGRSMLQSILDATPGHKVEASCLPASVVMARMLTNAGFHVKEISPFGKRT
                     FRR"
     gene            complement(1571..1933)
                     /locus_tag="IT892_004593"
     CDS             complement(1571..1933)
                     /locus_tag="IT892_004593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137699.1"
                     /translation="MVYFIPDTAVDPIEPVAYKIRFSFSNPDLLLKSAIEKYGEPSVS
                     DAQRGRYIWCKALAEKTNKCDDSKSELTLTTREVEDTGILTLSDPTVSFDASRTATAT
                     PDKDQAATEDNQGPLPQL"
BASE COUNT          520 a          455 c          486 g          501 t
ORIGIN      
        1 acctgcccat gaactcccgg attatatcca ctatcacctg gaacgggccg gagtgatctg
       61 tggacggtta cgtatcgttc gaagcaccaa gttccatatt attaagcccg ggagcgttgg
      121 ccgtacatcc cacaagatca ttgtaccgat gagccagtac gatgctgaat gcgtgattga
      181 agatgtcggc gcacttgaac aggcatacgc tttcgggatc ggcagaaagc ggatattcgg
      241 ctttggctat atgaacagca tcgaagtgct ttcctgaaca ggccattaag catagttatt
      301 atctgaattt caaaccgact cgcaaactta cggcattaac acttctgata caccctttaa
      361 atgctgtaaa ctgttgtagc ccttactaaa tcgtaagagt ggggatttgc agccccgact
      421 aatgacacgc cgttcatgta cttgaacggt tcgcactcgc tcgcctgttt tttgtcaatg
      481 gtgggtcggg gcgtgggagc cttacggctc gccagtcgtc attagctggt actgcaaacc
      541 atgttccgat tcaccaccaa aggaaatgga gatggaaaaa caggactggc ataaggcaga
      601 catcatagct gcgctacata agaaaggttt gtcacttgcc tcactgagta gggctaacgg
      661 tctttcaagc agcactctgg caaatgcact gacacgtgac tggcctagag gcgagatcat
      721 catcgctaat gcaattggtg aagaacctca agaaatatgg ccaacccgat attttgataa
      781 ggcaggaatg ccgatcaaga gaatcataag aaaaccggtt taaatgaaaa aggctggcat
      841 ttttgctggc cttatatacc tcctggctct gctactgaaa ccactaacac cgatcaaatg
      901 gtcatcagcg aaataccccg ttcatttcta ttgacctctt tacctccatg taatcaaatt
      961 gatggaataa taacggttac gagagacaaa ctgatgacgg tgttatctgc ccctgaaatg
     1021 cgctttggaa ccaaacagga tgttcccttt atcatagcgg tgattcgcga cggtatgcgg
     1081 gatgggtatt ttaactttga tgatgatgac ggactgtctc agttcgaaag tcagatctca
     1141 gaagccattg ccaggcggga acggggagag aattgcgccg atttcttgtt tgtctttgat
     1201 gctcaacata atggcgcagc gataggtttt gccctactga cgggcaaaaa tggtgcaaat
     1261 ggacttgctt cacatctgga aatcaggatg tttggtgtta ccaggagtca aagacaaaaa
     1321 ggatttgggc gctccatgtt gcaaagtatt ctggatgcta ctcccggcca taaagtggag
     1381 gcatcctgtc ttcctgcatc agttgtcatg gccaggatgc tgactaatgc gggttttcac
     1441 gtcaaagaga taagcccgtt tggaaagcgt actttcagac gctaatgtaa aattcagata
     1501 aaaaaaccgg ctgacgaatt cagtcggttt agtaatcctg caaaaggatg ctggacagcg
     1561 acggacgact tcagagctgt ggcaatggcc cctggttatc ttcagtcgca gcctggtctt
     1621 tatccggggt ggccgttgca gtccgcgagg catcaaatga gaccgttggg tcgctgagag
     1681 tcaggatgcc agtgtcttca acttctcgcg ttgtcagcgt aagctcagat ttactgtcat
     1741 cacacttatt cgttttctcc gccagtgcct tgcaccagat ataacgacct ctctgggcat
     1801 cagagactga aggctctcca tatttctcga tcgccgactt cagtaagaga tcagggttgc
     1861 tgaatgaaaa gcggattttg taagccaccg gctcaatggg gtcaactgcc gtatcgggga
     1921 taaaatagac caccgtctcc tggtgagcat ctccccagaa aa
//
LOCUS       DACAOP010000235         1944 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.239, whole genome shotgun sequence.
ACCESSION   DACAOP010000235 DACAOP010000000
VERSION     DACAOP010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1944
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.239"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>1944
                     /locus_tag="IT892_004594"
     CDS             <1..>1944
                     /locus_tag="IT892_004594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HAP3137700.1"
                     /translation="TQAQRAEEARQQAISGGTEPSAFPDTLPGYTEYGRDNGIRLSAV
                     WLTHDPEYPENLPAAPLVRYGWTPRGELAVVYDRSGKQVRSFTYDDKYRGRMVAHRHT
                     GRPEIRYRYDSDGRVTEQLNPAGLSYTYQYEKDHITITDSLDRREVLHTQGEAGLKRV
                     VKKEHADGSVTQSQFDAVGRLRAQTDAAGRTTEYSPDVVTGLITRITTPDGRASAFYY
                     NHHNQLTSATGPDGLELRREYDELGRLIQETAPDGDITRYRYDNPHSDLPCATEDATG
                     SRKTMTWSRYGQLLSFTDCSGYVTRYDHDRFGQMTAVHREEGLSQYRAYDSRGQLIAV
                     KDTQGHETRYEYNIAGDLTAVIAPDGSRNGTQYDAWGKAVRTTQGGLTRSMEYDAAGR
                     VIRLTSENGSHTTFRYDVLDRLIQETGFDGRTQRYHHDLTGKLIRSEDEGLVTHWHYD
                     EADRLTHRTVKGETAERWQYDERGWLTDISHISEGHRVAVYYGYDEKGRLTGERQTVH
                     HPQTEALLWQHETRHAYNAQGLANRCIPDSLPAVEWLTYGSGWLSGMKLGDTPLVEYT
                     RDRLHRETLRSFGRYELTTAYTPAGQLQSQHLNSLLSDRDYTWNDNGELIRISSPRQT
                     RSYSYSTTGRLTGVHTTAANLDIR"
BASE COUNT          458 a          588 c          598 g          300 t
ORIGIN      
        1 cacgcaggcg cagcgggcag aagaagcccg gcagcaggcc atttccggcg ggacggaacc
       61 gtccgctttt cctgataccc tgccgggtta caccgaatat ggccgggaca acggcatccg
      121 tctgtctgcc gtgtggctga cgcacgaccc ggaatacccg gagaatttac ctgccgcgcc
      181 gctggtgcgc tatggctgga cgccacgcgg cgaactggcg gtggtgtatg accgtagtgg
      241 caaacaggtg cgcagcttta cttacgatga taaataccgg ggccggatgg tggcgcaccg
      301 tcacacgggc cggccggaaa tccgttaccg ttacgacagc gacgggcggg tgacagaaca
      361 gcttaacccg gcaggcttaa gctacacgta tcagtatgag aaagaccaca tcaccatcac
      421 cgacagcctg gaccgccgtg aagtgctgca cacgcagggc gaagccgggc tgaagcgggt
      481 ggtgaaaaag gaacacgcgg acggcagcgt cacgcagagt cagtttgacg ccgtgggcag
      541 gctcagggca cagacggatg ccgcaggcag gacaacagag tacagcccgg atgtggtgac
      601 gggcctcatc acgcgcataa ccacgccgga tggcagggca tcggcgtttt actataacca
      661 ccacaaccag ttaacgtcag ccaccgggcc tgacgggctg gaattgcgcc gggaatatga
      721 tgaattgggc cgtctgattc aggaaactgc ccctgacggc gatatcaccc gctaccgtta
      781 tgataatcca cacagtgact taccctgcgc aacggaagat gccaccggca gccggaaaac
      841 catgacgtgg agccgttacg gtcagttgct gagcttcacc gactgttccg gttatgtaac
      901 ccgttatgac catgaccgct tcgggcagat gacggcggtg caccgcgagg aagggctgag
      961 tcagtaccgc gcatacgaca gccgtggaca gttaattgcc gtgaaagaca cgcagggcca
     1021 tgaaacgcgg tatgaataca acatcgccgg tgacctgacc gccgtcattg ccccggacgg
     1081 cagcagaaac gggacacagt acgatgcgtg gggaaaggcc gtccgtacca cgcagggcgg
     1141 gctgacgcgc agtatggaat acgatgctgc cggacgggtc atccgcctga ccagtgaaaa
     1201 cggcagccac accaccttcc gttacgatgt acttgaccgg ctgatacagg aaaccggctt
     1261 tgacggccgc acacagcgtt atcaccacga cctgaccggc aaacttatcc gcagcgagga
     1321 tgagggtctg gtcacccact ggcactatga cgaagcagac cgcctcacgc accgcaccgt
     1381 gaagggtgaa accgcagagc ggtggcagta tgacgaacgt ggctggctga cagacatcag
     1441 ccatatcagc gaagggcacc gggtggcggt gtattacgga tatgatgaga aaggccggct
     1501 gaccggtgag cgtcagacgg tgcatcaccc gcagacggaa gcactgctct ggcagcatga
     1561 gaccagacat gcgtacaacg cgcaggggct ggcgaaccgc tgtataccgg acagcctgcc
     1621 cgccgtggaa tggctgacct acggcagcgg ctggctgtca ggcatgaaac tcggcgacac
     1681 accgctggtg gagtacaccc gcgaccgcct gcaccgggaa acgctgcgca gcttcggccg
     1741 ttatgaactc accaccgctt atacccctgc cgggcagtta cagagccagc acctgaacag
     1801 cctgctgtct gaccgcgatt acacctggaa cgacaacggc gaactcatcc gcatcagcag
     1861 cccgcgccag acccggagtt acagctacag caccaccggc aggctgaccg gcgttcacac
     1921 caccgcagcg aatctggata tccg
//
LOCUS       DACAOP010000236         1937 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.240, whole genome shotgun sequence.
ACCESSION   DACAOP010000236 DACAOP010000000
VERSION     DACAOP010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1937
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.240"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..182)
                     /locus_tag="IT892_004595"
     CDS             complement(<1..182)
                     /locus_tag="IT892_004595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
                     /protein_id="HAP3137701.1"
                     /translation="MQQISFLPGEMTPGERSLILRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRV"
     gene            complement(197..682)
                     /locus_tag="IT892_004596"
     CDS             complement(197..682)
                     /locus_tag="IT892_004596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HAP3137702.1"
                     /translation="MTTVTHNSTTPSVSVTAASGNNPPQLVATLVPDEQRISFWPQHF
                     GLIPQWVTLEPRVFGWMDRLCENYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNA
                     MNGNRAEMSPEAAGITACLMTYSHHACRTENYAMTVHYYRLRDYALQHPECSAIMRII
                     D"
     gene            complement(774..1592)
                     /locus_tag="IT892_004597"
     CDS             complement(774..1592)
                     /locus_tag="IT892_004597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HAP3137703.1"
                     /translation="MRLASRFGHVNQIRRDRPLTHEELMHYVPSIFGEDRHTSRSERY
                     AYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRDGEINGQHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVEKVIEGAYEVVGVFD
                     RIEEKRDAMQSLVLPPPSRQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSARGKRIHTRTIHSIDTDIKLNRALWVMAETLLESMR"
BASE COUNT          442 a          510 c          546 g          439 t
ORIGIN      
        1 acccggaatt cttcacgctc cagtcccgcc atgttaagaa tcagccattc ccgtgctgca
       61 cgggtggagg tgaaggccac gccgggttca tgaagatggc ggtccagggt tttcagggcc
      121 cgcagaatga gactgcgctc gccgggcgtc atttctccgg gcagaaagga aatctgttgc
      181 attattccgg cccctttcag tcaatgatgc gcataatggc gctgcattcc ggatgctgca
      241 gggcgtaatc ccgcaaccgg taataatgga ccgtcatggc ataattctcc gtacgacagg
      301 catgatgact gtacgtcatc agacaggcgg taataccggc ggcttccggg ctcatttctg
      361 cgcggttacc gttcatggca ttgaacagta cccatgtttc gtcatcatca tcatccggtt
      421 cgggggccat aaatgccccg ccgttgttca gggtgtacag attccagata ccaccgcagt
      481 agttttcgca cagacggtcc atccagccga agacacgggg ctccagggtc acccactgtg
      541 gaatgaggcc aaaatgctgc ggccagaagc tgatgcgctg ttcatcaggg acgagagtag
      601 caaccagctg aggtgggtta ttccctgatg cagcggttac ggaaacagaa ggtgtggtgg
      661 aattatgcgt aacggttgtc atgagattat tccttataaa aagtaaatga atggaagaat
      721 gtccggaggc aggggcggaa gtgagtcagg actgcgcttt cagggaaaag gcatcagcgc
      781 atgctctcca gcagtgtttc tgccatcacc cacaacgccc ggttgagctt aatgtcggtg
      841 tcgatgctgt gaatggtacg ggtatggata cgttttcctc tggcactgcg accggaaatc
      901 ccgcctttca gcatattctc ctggatggtc tgataagcac tccacaggtc cttaccgtaa
      961 tcctcccggc gtcgtggcgt cagaatgtcg gcggtggtga cgggctgatg ttcgtcacca
     1021 taacggtaag tcagtgccgc ctgtgccagc gcctggcgtg acggtggcgg caggaccagc
     1081 gactgcatgg catcacgctt ctcctctatc cggtcaaaca cgcccaccac ctcgtaagcc
     1141 ccttcgataa ctttctccac cacatttccc cggtgtggaa cacgcacttc ccccagagac
     1201 tggccacaga cgcacccgtt ctggcagacg aacctgaagt aacccggcag catctggtag
     1261 ctggaagtac cgtcatggga gttcagcagg atgatttcag ggacatgttg tccgtttatc
     1321 tccccgtcac ggcgcagacg cagcatgtgt ttggtgtatc cccggcggcc cgggtcgcgc
     1381 acgcgggtct ggcaggcgaa gaagggctga aagccctccc gctgcaggct ttctagtacg
     1441 gtgatggtgg gaatgtacgc atagcgttca ctgcgggagg tatgccggtc ttccccaaaa
     1501 atactgggca catagtgcat cagttcttca tgtgtcagcg ggcggtcacg gcgtatctgg
     1561 tttacatgac caaaacgact tgctaatcgc attatttgct ccttatgaat gagttagcgg
     1621 tataaatgaa aaagccgcgt ctcccggaga agacgcggcc tgacagatga aatgaatgac
     1681 gtttattgtc tgagaagccc ttcactggcg agctgcgtat tttcatggaa ggagatcacc
     1741 caatatcccc atcgggatcg ggtaataact ggccagactg tgatcaattc agatgccatt
     1801 tggcagtaaa agggtcttcg ggcaataaac gtgatgcaca acccggcata tctgttgatc
     1861 cctgaaagta aaaggccccg gtcataatga ccggggcctg aagggaagtg acctgattat
     1921 cagaaagtca cgttcag
//
LOCUS       DACAOP010000237         1913 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.241, whole genome shotgun sequence.
ACCESSION   DACAOP010000237 DACAOP010000000
VERSION     DACAOP010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1913
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.241"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            72..386
                     /locus_tag="IT892_004598"
     CDS             72..386
                     /locus_tag="IT892_004598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001366610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137704.1"
                     /translation="MYNQKNKTGTVALSGTWQQGNRESKSIRRNIEYTWIENYDTAHL
                     TSKKVNKFEIMDQVDDDRLAELIPDFYVFPEKSVSYNILKQGKHAFILSIGNRAIMHC
                     AR"
     gene            complement(419..499)
                     /locus_tag="IT892_004599"
     CDS             complement(419..499)
                     /locus_tag="IT892_004599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137705.1"
                     /translation="MKDVDQNFDALYWHILQAYLILLFYD"
     gene            complement(535..960)
                     /locus_tag="IT892_004600"
     CDS             complement(535..960)
                     /locus_tag="IT892_004600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311733.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137706.1"
                     /translation="MDIEFSQIHEMVYMHDIVNSDSKKKPRIPLKKFLNAEKVLTQTT
                     SWVLNSRYVNVNSVSKVNVKSKVKNSYISRSVNDEFSLTDDEINSFKETLVLSSIDSL
                     SKLVLNNPLSVLFTSTVRRNNNRAKMNVEFDSWICTRCC"
     gene            1390..1881
                     /locus_tag="IT892_004601"
     CDS             1390..1881
                     /locus_tag="IT892_004601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137707.1"
                     /translation="MKPRNINNSLPLQPLVPDQENKNKKNEEKYVNPVKITMRSGLNY
                     IEQESLGGKYLTHDLSIKIADISEEIIQQAILSAMSIYKFPITDDLMSMATNELIKLA
                     KIENNLDLNKFSTICTDVLSPLVTRHNKEKKPDDLLPFAKIPFLIFIEKMEIDNMNPG
                     HAH"
BASE COUNT          724 a          311 c          303 g          575 t
ORIGIN      
        1 ataatgaaac atgcactgca aattgggtaa tttttaatga caaggggcga gcaaatctta
       61 ccatcgactt tatgtataac caaaaaaata aaacaggaac tgttgcgttg agcggaacct
      121 ggcaacaagg taacagagaa agtaagtcaa tacggcgaaa tattgaatac acatggattg
      181 aaaactatga cacagcccat ttaacatcaa agaaagttaa taaatttgag atcatggatc
      241 aagtcgatga tgatagactt gcagaactta ttcctgattt ttatgtcttt ccagaaaaaa
      301 gtgtaagcta taatatacta aagcaaggta agcatgcttt tattttgagt attggtaaca
      361 gagcaataat gcattgtgca aggtaaactt aaatagataa taaaaagatg gaacctcgtt
      421 aatcataaaa caataaaatt aaatatgctt gtagtatatg ccagtataaa gcatcaaagt
      481 tttgatcaac atctttcatt ttagatatca ccttgcaatg caaaatatca tgtatcaaca
      541 acatctggtg caaatccatg agtcgaactc aacattcatc ttagctctat tattattcct
      601 tcgtacagtc gatgtaaaca atacagaaag aggattatta agaaccagtt tacttagaga
      661 atcaatagag gaaaggacta acgtttcttt aaaagaattg atttcatcat ctgttaaact
      721 aaactcatca ttgacagatc gtgagatata actgttttta actttactct ttacgttgac
      781 tttactgaca gaattaacat tcacatatct tgaatttagt acccatgatg ttgtttgcgt
      841 gagaaccttc tcagcattaa ggaatttttt taacggaatc cttggtttct ttttcgagtc
      901 cgaatttaca atatcatgca tatagaccat ttcatgaatc tgcgaaaact caatgtccat
      961 tatatacctc acattttgac cgtgactcga tgttactgtt caataatcac cttccatcaa
     1021 tactaaattt aataccccta atgtgccgat aacaaatata gtcattctac gtaacgtctc
     1081 cataaggtga taaccttgat caaatgaatt tcgaaaataa taaaggaaat cttttgagat
     1141 gtttgtcacg aataaagcta tttatgttac caatatcatt tcgagtgtgc acactatcta
     1201 tctgtttttt caggatataa aaaacaacat gtaagttatg taaattgccg atgccactaa
     1261 gtaacattat ggtaaaaaaa gtaaaaatga gcgatttttg atagaataaa gcatgagaaa
     1321 aggtgatatt tgacattatc agaagctgcg aattcggatt ttgctctaat caaatgagag
     1381 aaatgtaaaa tgaagccacg aaatattaat aatagcctac cactgcaacc attagttcct
     1441 gatcaggaga acaaaaataa gaaaaatgaa gagaaatacg tgaatccagt taaaattacg
     1501 atgaggtctg gtttaaatta tattgaacaa gaatctcttg gaggaaaata tctaacacat
     1561 gatttgtcaa taaagatagc ggatatttct gaagaaataa ttcagcaagc aatattatcg
     1621 gctatgagca tatataaatt tccgataaca gatgatttaa tgagtatggc tacaaatgaa
     1681 ctcataaaac tggccaaaat agagaataat ttagacctga ataaattctc tactatatgt
     1741 accgacgttc tatcccccct cgtcaccaga cataataaag aaaaaaaacc agacgactta
     1801 ctacccttcg caaaaatccc ttttttaatt ttcatcgaaa aaatggaaat tgataatatg
     1861 aatccaggcc atgcacatta aggcatttat gaaatgtcgt aattaagata act
//
LOCUS       DACAOP010000238         1866 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.242, whole genome shotgun sequence.
ACCESSION   DACAOP010000238 DACAOP010000000
VERSION     DACAOP010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1866
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.242"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(300..410)
                     /locus_tag="IT892_004602"
     CDS             complement(300..410)
                     /locus_tag="IT892_004602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137708.1"
                     /translation="MEIKVQRLSLWMINTVFLLSPINNHQTNTINLIFEM"
     gene            complement(463..867)
                     /locus_tag="IT892_004603"
     CDS             complement(463..867)
                     /locus_tag="IT892_004603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 domain-containing protein"
                     /protein_id="HAP3137709.1"
                     /translation="MDQVVVFQKMFEQVRKEQNFSWFYSELKHHRIAHYIYYLATDNI
                     RIITHDDTVLLLRGTRNLLKVSTTKNPAKIKEAALLHICGKSTFREYCSTLAGAGVFR
                     WVTDVNHNKRSYYAIDNTLLYIEDVENNKPLI"
     gene            complement(1088..1819)
                     /locus_tag="IT892_004604"
     CDS             complement(1088..1819)
                     /locus_tag="IT892_004604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP3137710.1"
                     /translation="MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDE
                     EDIQRIEEIKRWISNGVPVGKVKALLETTSQDTEDDWSRLQEEMMSILRMANPAKLRA
                     RIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAATSLFEMRRK
                     PGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIESPRPELFPTQTLIVWTGM
                     APTRRQNELLQHWGEQGYKVIFHAP"
BASE COUNT          523 a          389 c          386 g          568 t
ORIGIN      
        1 atgactgaac atcctgtaat taaaacatag cctttatgct actttgtgcc aatttgctaa
       61 acattatggt tgccttttta tataacgata ataatgaata taagcatgac atgagaataa
      121 ggtttcaatt tttgagttat ataggaatga tttaacctgt tcctggctaa aatacatata
      181 accggatgat gactaaacca aaatacatgt gcgttaagta ttgaaacgga cgtgtggcac
      241 ggccgttgtt tttataaata tgttaaccgt tataaaataa cgtatcaaaa gtcaagtgat
      301 cacatttcaa atatcaagtt gatagtatta gtctggtgat tatttatggg tgacaataaa
      361 aagacagtat taatcatcca tagagatagt ctctgcactt ttatttccat tatgctaatg
      421 ccttactgaa ttatgaagca tttcttaagt atccaacttt agctagatta atggtttatt
      481 attttctaca tcttcaatat ataaaagcgt attatcaatg gcgtagtaac tgcgtttgtt
      541 atgattaaca tcagtaaccc accggaaaac gcccgcgcct gccagtgttg aacagtattc
      601 ccgaaatgta gattttccgc aaatatgaag caatgcggcc tcttttattt tagcagggtt
      661 cttggtcgta ctaactttta acaggttcct ggttcctctt aataacaaaa ccgtatcatc
      721 gtgagtaata attctgatgt tatccgtagc cagataataa atgtaatgtg caatacggtg
      781 atgttttaat tctgaataaa accaggagaa gttttgctct tttctcactt gctcaaacat
      841 cttttgaaaa acaacgacct gatccatcag gataataacc tcttgttagt tgtgagactg
      901 cgtagtgtgc acgatcggtt ttaccacttc aatctggtct gtcctttggc tgtgatatgt
      961 acagagtgtg atagagggaa tatctgaatt ctcccggtga gcattttgca acggaccagc
     1021 tccggtacaa acgctgttgt gggttcagat tataacattc tgtctaaggg gcgggataaa
     1081 ggtgaaatta gggggcatga aagatgactt tataaccttg ctcaccccag tgttgtaaaa
     1141 gttcgttttg ccttctcgtt ggtgccatgc ctgtccagac aatcaatgtt tgcgtcggga
     1201 acagttccgg gcgcggcgat tcaatgggat cagcaagaac agaaatgtgc catcctgaca
     1261 atgataaacg ccatgcttcc agccacaatc gtgctctctc ttcaacattc cacgccatca
     1321 gaatggcttc tttaccgggc ttacggcgca tttcgaaaag cgaggttgct gcgtattcaa
     1381 ttaatgcgcc gtcaaacata ctgctcataa tgcgggaggt gttgtgatca agcacgagac
     1441 gctggcgaac aggaaggtaa acatgattaa tcaattgatc tactgggtac tctcgaccca
     1501 gtgaaataat tctcgcgcgt agtttggcag gattagccat gcgaagaatt gacatcatct
     1561 cttcttgcag gcggctccag tcatcttccg tatcctggct ggtggtttcc agtaatgctt
     1621 taactttgcc tacagggacg ccattactta tccaacgctt gatctcttcg atgcgttgta
     1681 tgtcttcttc atcaaagagt cggtgtccgc cttcactgcg ctgtggtttt aacaaaccgt
     1741 agcggcgttg ccaggcccgg agagtgacag gattaatccc gcaacgttca gcaacatcac
     1801 caatgctgta ataagccaca attcctcctt gcggtcacaa atctccgtcg cctgtacacg
     1861 acccaa
//
LOCUS       DACAOP010000239         1845 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.243, whole genome shotgun sequence.
ACCESSION   DACAOP010000239 DACAOP010000000
VERSION     DACAOP010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1845
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.243"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..515)
                     /locus_tag="IT892_004605"
     CDS             complement(<1..515)
                     /locus_tag="IT892_004605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscT/YscT/HrcT family type III secretion system
                     export apparatus protein"
                     /protein_id="HAP3137711.1"
                     /translation="MGEAMLYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRH
                     PIIIVVSCALVQHYHYELSTLNEIDIALFAAREIIIGLFIACLLASPFWIFLAIGSFI
                     DNQRGATLSSTLDPATGVDTSELARLFNLFSAAVYLTNGGLNFILETLWQSYNLWPSG
                     NFNFPKLEPLFS"
     gene            complement(517..777)
                     /locus_tag="IT892_004606"
     CDS             complement(517..777)
                     /locus_tag="IT892_004606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscS/YscS/HrcS family type III secretion system
                     export apparatus protein"
                     /protein_id="HAP3137712.1"
                     /translation="MDDIVFAGNRALYLILVMSAGPIAVATFVGLLVGLFQTVTQLQE
                     QTLPFGVKLLCVSICFFLMSGWYGEKLYSFGIEMLNLAFARG"
     gene            complement(787..1452)
                     /locus_tag="IT892_004607"
     CDS             complement(787..1452)
                     /locus_tag="IT892_004607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscR/YscR/HrcR family type III secretion system
                     export apparatus protein"
                     /protein_id="HAP3137713.1"
                     /translation="MSNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRNALGLQ
                     QVPSNMTLNGVALLLSMFVMMPVGKEIYNNSQNENLSFNNVASVVNFVETGMSGYKSY
                     LIKYSEPELVSFFEKIQKVNSSEDNEEIIDDDNISIFSLLPAYALSEIKSAFIIGFYI
                     YLPFVVVDLVISSVLLTLGMMMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLS
                     INP"
     gene            complement(1442..>1845)
                     /locus_tag="IT892_004608"
     CDS             complement(1442..>1845)
                     /locus_tag="IT892_004608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YscQ/HrcQ family type III secretion apparatus
                     protein"
                     /protein_id="HAP3137714.1"
                     /translation="AYAVIYNTKICDLIYPEELKMVDHFEYEEDFETDDFDIKKSEIE
                     INDENDYQQINSFEDLPVKIEFVLGKKIMNLYEIDDLCAKRIISLLPEAEKNIEIRVN
                     GALTGYGELVEVDDKLGVEIHSWLSGNNNVK"
BASE COUNT          641 a          394 c          273 g          537 t
ORIGIN      
        1 gagaataaag gctctaattt aggaaaatta aaatttcctg aaggccataa gttataactt
       61 tgccatagag tctccagaat aaagttcaat ccaccgttag taagataaac tgctgcagag
      121 aaaaggttaa ataatcttgc taattccgat gtatcgacac ctgtagccgg atccaaagta
      181 ctacttaacg ttgcaccacg ttggttatcg ataaagctac ctatagcaag gaaaatccaa
      241 aatggggatg ctaataagca agcaataaac aaccctatga taatttctct ggcagcaaac
      301 aaagcgatat ctatttcatt tagggtagat aattcatagt ggtaatgctg aactaatgca
      361 catgatacca ctattattat tggatgacgg actactgttg gtatattccc actggcgaaa
      421 aatggtaaca aatagaaagt tggtgccaat cggcaaaaac cgagcgctgt agcagccagc
      481 agactatgca actgatagag catcgcctcc cccatgctat cctctcgcga atgctaaatt
      541 cagcatttcg ataccaaacg aatataattt ttcaccatac catccgctca ttaaaaaaaa
      601 gcaaatactt acgcacaata atttgacgcc aaatggcaac gtctgttctt gcaactgtgt
      661 taccgtttga aaaagcccta ccaataaacc aacaaatgtc gcaactgcaa taggtcctgc
      721 agacataact aaaatcagat acagcgccct attccccgca aaaacaatgt cgtccatatt
      781 ttttcctcag ggattaatgg ataggtcaaa atattgtaaa atgagtcctt tcgataacat
      841 tgtccaaccg tccatcgcga caaacagaat taattttatc ggtgtagata tggttaccgg
      901 actcatcatc atcataccta acgttaacag aacgctggat ataaccagat caactacaac
      961 aaagggtaaa taaatataaa aacctataat aaatgcactt tttatctcac tcaacgcata
     1021 tgccgggagt aacgagaaaa ttgaaatatt atcatcatcg attatctctt cattgtcttc
     1081 agaactattc accttctgaa tcttttcaaa aaagctaacc aactccggtt cagaatattt
     1141 tatcaaatat gatttataac cactcatgcc tgtctcaaca aaattaacaa ccgacgcaac
     1201 attattgaat gaaagattct cattctgact gttattatat atttccttcc caaccggcat
     1261 cattacgaac attgacaata gcaaagctac cccattaagt gtcatatttg atggcacttg
     1321 ctgaagtccc aaagcgtttc ggacaataac aaaaacaatc gagaatttaa taaaacatgt
     1381 cccggatgct attataaacg gtaatagtgt gaataatgat aatatcgcta tcagcgaaat
     1441 gctatttgac attattattc cctgataacc aagaatgaat ttctacgccc aatttatcat
     1501 ccacttcaac aagttcgcca tagccagtta gcgcgccatt tacacgtatc tctatatttt
     1561 tctccgcttc aggaagcaaa gatataattc tttttgcaca gagatcgtct atttcatata
     1621 gattcattat tttcttacca agaacaaact caatttttac aggcaggtct tcaaaactat
     1681 taatctgctg atagtcattt tcatcattaa tctcgatttc gctttttttg atatcaaagt
     1741 catctgtttc aaaatcttcc tcgtactcaa aatgatcaac catttttaac tcctctggat
     1801 aaattaaatc acaaatcttt gtattataaa taaccgcata agcaa
//
LOCUS       DACAOP010000240         1811 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.244, whole genome shotgun sequence.
ACCESSION   DACAOP010000240 DACAOP010000000
VERSION     DACAOP010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1811
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.244"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(17..169)
                     /locus_tag="IT892_004609"
     CDS             complement(17..169)
                     /locus_tag="IT892_004609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HAP3137715.1"
                     /translation="MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     gene            622..1740
                     /locus_tag="IT892_004610"
     CDS             622..1740
                     /locus_tag="IT892_004610"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HAP3137716.1"
                     /translation="MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNK
                     ITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAATDHHLEICGGGTHPF
                     QKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPH
                     FIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMID
                     SIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKD
                     YLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKIGASSAIEAL
                     HRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD"
BASE COUNT          465 a          477 c          416 g          453 t
ORIGIN      
        1 actccccgca caacggctac ttcttcggtt cgtaagcgag aacagcctta aactcaatat
       61 tacgttcctt caccgtaaac tcacacagcg agtctccgac cagaagcgta aatcccagca
      121 ccgttaaaca cagcactatg actgccgcaa gggcatattt cgtcagcatg tttatattgc
      181 ctccatgcga agaagggact accatccaaa ttgttcgggt ttggagtggc agccccaggg
      241 ttgatagaaa tatctcctgg ggcttcatct ttccagacct cagagtaaac ctgaaaccgg
      301 aaagcttcag gcacccgccg ttatcttacc cttcctcaac aaaatagctg tttatttata
      361 cagtgagtcc tgtttcggac ttctcactcc tcatttaatc aactgaagct gaacccgttt
      421 ttttctgcat gactcaatcg tcaaaattct tcgccaccag tcagcactgc cataacttgt
      481 cacattgcaa aagtagccaa attgcttcag gcaccatcag ttcaccatca ccaaaaaaaa
      541 gaaacattcc agaacttccg catctcgccc agccgctccg acttctatac tgaatagaaa
      601 acgccaacat aagagaaacc tatgccatta cccgattttc atgtttctga accttttacc
      661 ctcggtattg aactggaaat gcaggtggtt aatccgccgg gctatgactt aagccaggac
      721 tcttcaatgc tgattgacgc ggttaaaaat aagatcacgg ccggagaggt aaagcacgat
      781 atcaccgaaa gtatgctgga gctggcgacg gatgtttgcc gtgatatcaa ccaggctgcc
      841 gggcagtttt cagcgatgca gaaagtcgta ttgcaggcag ccacagacca tcatctggaa
      901 atttgcggcg gtggcacgca cccgtttcag aaatggcagc gtcaggaggt atgcgataac
      961 gaacgctatc aacgcacgct ggaaaacttt ggttatctca ttcagcaggc gaccgttttt
     1021 ggtcagcatg tccatgttgg ctgcgccagt ggcgatgacg ccatttattt gctgcacggc
     1081 ttgtcacgat ttgtgccgca ctttatcgcc ctttccgccg cgtcgccata tatgcaggga
     1141 acggatacgc gttttgcctc ctcacgaccg aatatttttt ccgcctttcc tgataatggc
     1201 ccgatgccgt gggtcagtaa ctggcaacaa tttgaagccc tgtttcgctg tctgagttac
     1261 accacgatga tcgacagcat taaagatctg cactgggata ttcgccccag tcctcatttt
     1321 ggcacggtgg aggttcgggt gatggatacc ccgttaaccc ttagccacgc agtaaatatg
     1381 gcgggattaa ttcaggctac cgcccactgg ttactgacgg aacgcccgtt taaacatcag
     1441 gaaaaagatt acctgctgta taaattcaac cgtttccagg cctgtcgcta tgggcttgaa
     1501 ggcgtcatca ccgatccgca cactggagat cgtcgaccgc taacggaaga taccttgcga
     1561 ttgctggaaa aaatcgcccc ttccgcacat aaaattggtg catcgagcgc gattgaggcc
     1621 ctgcatcgcc aggtcgtcag cggtctgaat gaagcgcagc taatgcgcga tttcgtcgcc
     1681 gatggcggct cgctgattgg gctggtgaaa aagcattgtg agatctgggc cggtgactaa
     1741 gccgggaatt gccttacaga agaatatccc tgacaatggt gttttaactt acatttaaca
     1801 atgttatgaa a
//
LOCUS       DACAOP010000241         1792 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.245, whole genome shotgun sequence.
ACCESSION   DACAOP010000241 DACAOP010000000
VERSION     DACAOP010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1792
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.245"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(1..218)
                     /locus_tag="IT892_004611"
                     /pseudo
     CDS             complement(1..218)
                     /locus_tag="IT892_004611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415974.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(202..>1792)
                     /locus_tag="IT892_004612"
     CDS             complement(202..>1792)
                     /locus_tag="IT892_004612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HAP3137717.1"
                     /translation="ISGPRQTREYGYSATGRLESVRTLAPDLDIRIPYATDPAGNRLP
                     DPELHPDSTLTVWPDNRIAEDAHYVYRHDEYGRLTEKTDRIPAGVIRTDDERTHHYHY
                     DSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRERDLTGWMSLSRKPEVTWY
                     GWDGDRLTTVQTDTTRIQTVYEPGSFTPLIRVETENGEREKAQRRSLAETLQQEGSEN
                     GHGVVFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLARQVEPEYTPARKA
                     HLYHCDHRGLPLALISEDGNTAWSAEYDEWGNQLNEENPHHVYQPYRLPGQQHDEESG
                     LYYNRHRHYDPLQGRYITPDPIGLRGGWNMYQYPLNPIQVIDPMGLDAIENMTSGGLI
                     YAVSGVPGLIAANSITNSAYQFGYDMDAIVGGAHNGAADAMRHCYLMCRMTKTFGSTI
                     ADVIGKNHEAAGDRQGQPAKERIMDLKNNTVGIACGDFSAKCSDACIEKYNTGQLFGL
                     DGIKADNPIKAKQGSSDASNY"
BASE COUNT          364 a          532 c          415 g          481 t
ORIGIN      
        1 tatacttata aaatgaccat tccctctact aattttttgg tcattaatta ttttataaat
       61 aatatttttt cagaaagata tatctcaacg ctctttggtg ttttatgtcc ataaaatacg
      121 atgtcagaat ttgaattgtt atcaaaccca aggtaaacaa caaataaaca aagggtaatt
      181 aaaaaaatga caagtttgcc tctaataatt tgaagcatct gaactccctt gctttgcttt
      241 tattggatta tctgctttta taccatctaa cccgaagagt tgcccagtgt tatatttttc
      301 aatacatgca tcgctacatt tggcagaaaa atcgccacaa gcaataccga cagtgttatt
      361 tttaagatcc atgattcttt ctttagctgg ctgaccttgt ctatcccctg ccgcctcatg
      421 atttttacct atcacgtcag ctattgttga tccaaatgtc ttagtcattc gacacatcaa
      481 gtaacaatgt ctcattgcat cggcggcccc attatgagct ccgccaacaa tagcatccat
      541 atcataaccg aactggtaag cactgttagt aatgctgttt gcagcaatca atccaggtac
      601 accagatacg gcataaatta gtccacctga tgtcatattc tcaatcgcat ctaaccccat
      661 tgggtctatc acttgtatgg gattcaacgg atactgatac atattccatc cacctctcaa
      721 cccaatcggg tccggggtga tataccgccc ctgcaacgga tcgtagtgcc ggtgacggtt
      781 atagtacagc cctgattcct catcatgctg ctgccctggc agacggtacg gctgatacac
      841 atgatgcggg ttctcctcat taagctggtt gccccattca tcatattccg cgctccacgc
      901 cgtattgccg tcttcgctga taagcgccag cggcagtccc cggtggtcgc agtgataaag
      961 atgagctttt cgcgccggtg tgtattccgg ctccacctgt ctggccagtt gctccaccgt
     1021 cagcccgcac tgcgcaagcc acgcccggct ttcactgctc acgcggtctg cccggatttc
     1081 ttcctccagc ctgtccagca gccgcaccag ttcagccggg aacaccacgc cgtggccgtt
     1141 ctcactccct tcctgctgga gcgtctctgc caggctgcgc cgctgcgctt tttcccgctc
     1201 gccgttctct gtctcgaccc ggatgagcgg cgtgaagctt cccggctcgt ataccgtctg
     1261 gatacgtgtg gtgtcagtct gcaccgtcgt cagcctgtct ccgtcccagc cataccacgt
     1321 cacctccggt ttacgcgaca gcgacatcca ccccgtcagg tcacgctccc gccgccagac
     1381 ccgttttgcc attcgccgtc ccagcgggtc gtagaggtag cggctctcga ccagtggctc
     1441 gccatgctgt atccgcgtgt agaacaccag gcggtgctgg ctgtcgtagt ggtagtggtg
     1501 ggtccgctcg tcgtccgtcc gtatcacacc cgccgggatg cggtccgtct tctccgtcag
     1561 cctgccgtat tcatcgtggc ggtagacata gtgcgcatcc tccgcgatgc ggttatccgg
     1621 ccacactgtg agtgtactgt ccgggtgcag ctccgggtcc ggcagccggt tgcccgccgg
     1681 gtccgtggca tacgggatgc ggatgtccag gtctggtgcg agggtgcgca cactctccag
     1741 cctgcccgtg gcgctgtagc cgtattcccg cgtctgtcgc gggccgctga tg
//
LOCUS       DACAOP010000242         1741 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.248, whole genome shotgun sequence.
ACCESSION   DACAOP010000242 DACAOP010000000
VERSION     DACAOP010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1741
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.248"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            91..1104
                     /gene="intI1"
                     /locus_tag="IT892_004613"
     CDS             91..1104
                     /gene="intI1"
                     /locus_tag="IT892_004613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="HAP3137718.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAF
                     IRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQ
                     EIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDF
                     DHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALER
                     KYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTFQRAFKRAVEQAGITKPATP
                     HTLRHSFATALLRSGYDIRTVQDLLGHSDVSTTMIYTHVLKVGGAGVRSPLDALPPLT
                     SER"
     gene            1307..1657
                     /locus_tag="IT892_004614"
     CDS             1307..1657
                     /locus_tag="IT892_004614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3330 domain-containing protein"
                     /protein_id="HAP3137719.1"
                     /translation="MEVVAEGVETPDCLAWLRQAGCDTVQGFLFARPMPAAAFVGFVN
                     QWRNTTMNANEPSTSCCVCCKEIPLDAAFTPEGAEYVEHFCGLECYQRFQARASTATE
                     TSVKPDACDSPPSG"
     gene            1677..1741
                     /locus_tag="IT892_004615"
                     /pseudo
     CDS             1677..1741
                     /locus_tag="IT892_004615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
BASE COUNT          327 a          523 c          533 g          358 t
ORIGIN      
        1 cataacatca aacatcgacc cacggcgtaa cgcgcttgct gcttggatgc ccgaggcata
       61 gactgtacaa aaaaacagtc ataacaagcc atgaaaaccg ccactgcgcc gttaccaccg
      121 ctgcgttcgg tcaaggttct ggaccagttg cgtgagcgca tacgctactt gcattacagt
      181 ttacgaaccg aacaggctta tgtccactgg gttcgtgcct tcatccgttt ccacggtgtg
      241 cgtcacccgg caaccttggg cagcagcgaa gtcgaggcat ttctgtcctg gctggcgaac
      301 gagcgcaagg tttcggtctc cacgcatcgt caggcattgg cggccttgct gttcttctac
      361 ggcaaggtgc tgtgcacgga tctgccctgg cttcaggaga tcggaagacc tcggccgtcg
      421 cggcgcttgc cggtggtgct gaccccggat gaagtggttc gcatcctcgg ttttctggaa
      481 ggcgagcatc gtttgttcgc ccagcttctg tatggaacgg gcatgcggat cagtgagggt
      541 ttgcaactgc gggtcaagga tctggatttc gatcacggca cgatcatcgt gcgggagggc
      601 aagggctcca aggatcgggc cttgatgtta cccgagagct tggcacccag cctgcgcgag
      661 cagctgtcgc gtgcacgggc atggtggctg aaggaccagg ccgagggccg cagcggcgtt
      721 gcgcttcccg acgcccttga gcggaagtat ccgcgcgccg ggcattcctg gccgtggttc
      781 tgggtttttg cgcagcacac gcattcgacc gatccacgga gcggtgtcgt gcgtcgccat
      841 cacatgtatg accagacctt tcagcgcgcc ttcaaacgtg ccgtagaaca agcaggcatc
      901 acgaagcccg ccacaccgca caccctccgc cactcgttcg cgacggcctt gctccgcagc
      961 ggttacgaca ttcgaaccgt gcaggatctg ctcggccatt ccgacgtctc tacgacgatg
     1021 atttacacgc atgtgctgaa agttggcggt gccggagtgc gctcaccgct tgatgcgctg
     1081 ccgcccctca ctagtgagag gtagggcagc gcaagtcaat cctggcggat tcactacccc
     1141 tgcgcgaagg ccatcggtgc cgcatcgaac ggccggttgc ggaaagtcct ccctgcgtcc
     1201 gctgatggcc ggcagcagcc cgtcgttgcc tgatggatcc aacccctccg ctgctatagt
     1261 gcagtcggct tctgacgttc agtgcagccg tcttctgaaa acgacaatgg aggtggtagc
     1321 cgagggtgtg gaaacacccg actgccttgc gtggttgcgg caggcgggtt gcgacacggt
     1381 gcagggtttc ctgttcgcca ggccgatgcc ggcggcggcc ttcgtcggct tcgtcaacca
     1441 atggaggaac accaccatga acgccaatga accgagcacc agttgctgcg tgtgctgcaa
     1501 ggaaatcccg ctcgatgccg ccttcacgcc ggaaggggcc gagtacgtgg agcatttctg
     1561 cgggctggag tgctatcagc gcttccaggc gcgggccagc actgcgaccg aaaccagcgt
     1621 caaaccggac gcttgtgatt cgccgccgtc aggttgaggc ataccctaac tggattgtca
     1681 ttttcagaag acgactgcac cagttgattg ggcgtaatgg ctgttgtgca gccagctcct
     1741 g
//
LOCUS       DACAOP010000243         1555 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.249, whole genome shotgun sequence.
ACCESSION   DACAOP010000243 DACAOP010000000
VERSION     DACAOP010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1555
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.249"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            187..1305
                     /gene="gmd"
                     /locus_tag="IT892_004616"
     CDS             187..1305
                     /gene="gmd"
                     /locus_tag="IT892_004616"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HAP3137720.1"
                     /translation="MKKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRSSSFNTDRV
                     DHIYQDPHSSNPKFHLHYGDLTDTSNLTRLLSEIKPDEVYNLGAMSHVAVSFESPEYT
                     ADVDAIGTLRLLDAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRGLSNIAQGLEKCLYL
                     GNMDSLRDWGHAKDYVKMQWLMLQQEQPEDYVIATGVQYSVRQFVDFAASELGIKLRF
                     EGHGVDEVGIVESVSGEDAPAVNVGDVIVAVDPRYFRPAEVETLLGDPSKAHYKLGWK
                     PETTLQEMVVEMVRKDLEAAKKHSLLKSHGYEVSISLE"
     gene            1310..>1555
                     /locus_tag="IT892_004617"
     CDS             1310..>1555
                     /locus_tag="IT892_004617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001575929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAP3137721.1"
                     /translation="MTIKKRVFVAGHNGMVGSAIVRQLKNRDDIELVLRSRQEINLLN
                     AQDVNDFFANERIDEVYLAAAKVGGIVANNTFPADFIY"
BASE COUNT          450 a          266 c          356 g          483 t
ORIGIN      
        1 tccggttggg ttttttggat ggctcaaaag gatgggattt tcatttaatg caaggtttgt
       61 ggtatagaag ttacgttgat attagatata aggagttgga tgcactcatt tctgatataa
      121 gcagtgatcg tgaaaaatta aacgtattat ctaaatcaac tggtttaagt ctctgaggaa
      181 ataaatatga aaaaggttgc attaattacg ggcgttactg gtcaggatgg ttcttatctt
      241 gcagagtttt tactcgagaa aggatatgaa gttcatggta ttaaacggcg gtcttcttca
      301 tttaacacag atcgtgttga tcatatttat caagatccgc actcatcaaa tccgaagttc
      361 catcttcatt atggcgattt aactgatact tctaacctga cgagactttt atcagaaata
      421 aaacctgatg aggtctacaa cttgggggct atgagtcacg ttgctgtttc tttcgaatca
      481 ccagaatata ctgctgatgt tgatgctatt ggtactcttc gtcttctaga tgctattcgt
      541 tttctggggc ttgagaaaaa aacccgtttc tatcaggcat ctacttctga actatatggt
      601 ctagtgcagg aaattccgca aaaagagaca actccattct atcctcgttc accatatgca
      661 gtagcgaaac tttatgcata ttggattacg gttaactatc gtgagtcata tggaatgtac
      721 gcgtgcaatg gtattctgtt taaccatgaa tcaccacgcc gtggcgaaac gtttgtaaca
      781 cgaaaaatta cacgtgggct ttccaatatt gctcaaggtt tagaaaaatg tctttatctt
      841 ggtaatatgg actccttacg agactggggg catgcgaaag actatgtcaa aatgcaatgg
      901 ttaatgctgc aacaagagca accggaagat tatgttattg caacaggcgt ccaatactcg
      961 gtacgtcaat tcgttgactt tgccgcatcc gagttgggta ttaaattacg ctttgagggg
     1021 catggcgttg atgaagtcgg aattgtagag agtgtttctg gtgaagatgc acctgcagtt
     1081 aacgtaggtg acgtaattgt agctgttgat ccgcggtatt tccgtcctgc tgaagtggaa
     1141 accttacttg gagacccttc gaaagctcac tataaattgg gctggaaacc tgaaacaacc
     1201 ttacaagaga tggttgtcga aatggttaga aaggatcttg aggctgctaa aaagcattct
     1261 ctactcaaat cacatggtta cgaggtttcg atttctctgg agtaaagaaa tgacaattaa
     1321 gaagagagtt tttgttgctg ggcataatgg tatggttggg tcagcaatcg taagacaatt
     1381 gaaaaataga gacgacattg agctcgtact gcgttcacgt caagagatca acctgcttaa
     1441 tgctcaagac gtgaatgatt ttttcgctaa tgagcgtatt gatgaagtat atttagctgc
     1501 tgcaaaagtt ggcggaatag ttgcgaataa tacttttcct gctgatttta tatat
//
LOCUS       DACAOP010000244         1554 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.250, whole genome shotgun sequence.
ACCESSION   DACAOP010000244 DACAOP010000000
VERSION     DACAOP010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1554
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.250"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..938)
                     /gene="emrD"
                     /locus_tag="IT892_004618"
     CDS             complement(<1..938)
                     /gene="emrD"
                     /locus_tag="IT892_004618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418129.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EmrD"
                     /protein_id="HAP3137722.1"
                     /translation="MKRQRNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGA
                     VQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVGMSIFMLATLVAVTTSSLTVLIAA
                     SAMQGMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWN
                     WRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTLFGNSGFNCYLLMLIG
                     GLAGIAAFEACSGVLMGAVLGLSSMTVSILFILPIPAAFFGAWFAGRPNKRFSTLMWQ
                     SVICCLLAGLLMWIPDWFGVMNVWTLLVPAALFFFGA"
     gene            complement(1218..1307)
                     /gene="tisB"
                     /locus_tag="IT892_004619"
     CDS             complement(1218..1307)
                     /gene="tisB"
                     /locus_tag="IT892_004619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin TisB"
                     /protein_id="HAP3137723.1"
                     /translation="MNLVDIAILILKLIVAALQLLDAVLKYLK"
BASE COUNT          439 a          420 c          392 g          303 t
ORIGIN      
        1 gcaccgaaaa agaacagcgc ggcgggaacg agcagcgtcc agacattcat cacgccaaac
       61 cagtcgggga tccacatcag caagccagcc agcaggcagc agataaccga ctgccacatt
      121 aacgtggaga agcgtttatt gggacgtccg gcaaaccatg cgccaaaaaa cgctgccgga
      181 atcggcagaa taaacaaaat actgaccgtc atactgctca gccctaacac cgcgcccatc
      241 agcacgccgg agcaggcttc aaaggcggca atcccggcca gaccgccaat cagcatcagc
      301 aaataacagt taaaaccgct gttaccgaaa agcgttttat aactggtaag caggcgcgtg
      361 cgcggtgcat cgaccggacg cgtttccggc atccagcggg ccatactgaa ggtcacacca
      421 gcacaaagaa ccaacaaaaa gagataacag gcgcgccagt tccacatcgt atccagcaga
      481 ccgccgatta gcggtgcgag caacggactg acgagaatcc ccatgtttaa caggctgtta
      541 gcatggcgca actgtgtccg ttcatataaa tctcgcggta aagtacgcgc cattacgccg
      601 ccaacgccgg tgcccatccc ctgcatcgcg ctggcggcaa tcaacaccgt caaactggag
      661 gtcgtgaccg cgaccagcgt tgccagcata aaaatggaca ttccgacgag gatcaccggt
      721 cggcggccca cgcggtcgga aatcgggcca taaaacagct gtgagacacc gtaagtcagc
      781 agataagcgc ccattacgct ctgcaccgcc ccttcacgga cgttgagatc gcgcgccata
      841 tcggcaatag ctggaatata aatggtttgc gccatctgac cgacggccac gagtaatacc
      901 aacatcaata acaaattgac gtttctttgc cttttcatta tcacggatgc ttttataaaa
      961 ataattagaa taagtcacta cgcattccca taaatgcggg agaggaatct atcacattga
     1021 tgaatgttag ccagatatac gccaggaatg gggaattgtt tagcggcaga atatgtaaac
     1081 aaaagcggca ataaatgttg ccgggagaga tggtagggcg gataagatgc gtcagcatcg
     1141 catccgacac caacccgcac gctaaatata aaaggggagc ggtttcccgc tcccctttgg
     1201 tgcgacttga atctgaatta cttcaggtat ttcagaacag catcaagcag ttgcagtgct
     1261 gcaacaatga gtttgaggat aagaatggcg atatccacca ggttcatacg cgtctcctgt
     1321 ggttcaggag cactgccagc tgacgtacct ttccgctgcc tgttgccagc tgttgtgcac
     1381 gcggtatctc aaggagaaac gttgtgcttg ttgacataac acagtgtgct cacgcggggt
     1441 taaggcgctg acggcaccac ccgtttcagc caggacttag tgcgccgggt aacgatgcgg
     1501 cccccgcata acacattgcg tacagtgata ttatagaagt ttactgtata aata
//
LOCUS       DACAOP010000245         1527 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.251, whole genome shotgun sequence.
ACCESSION   DACAOP010000245 DACAOP010000000
VERSION     DACAOP010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1527
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.251"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(94..882)
                     /locus_tag="IT892_004620"
     CDS             complement(94..882)
                     /locus_tag="IT892_004620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /protein_id="HAP3137724.1"
                     /translation="MGEFFPAQVFKQLSHARAVIERHLAATLDTIHLFGSAIDGGLKP
                     DSDIDLLVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWRYP
                     ARRELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSAATFFEPVPKE
                     HFSKALFDTIAQWNAESDWKGDERNVVLALARIWYSASTGLIAPKDVAAAWVSERLPA
                     EHRPLICKARAAYLGSEDDDLAMRVEETAAFVRYAKATIERILR"
     gene            complement(1013..1486)
                     /locus_tag="IT892_004621"
     CDS             complement(1013..1486)
                     /locus_tag="IT892_004621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA17"
                     /protein_id="HAP3137725.1"
                     /translation="MKISLISAVSENGVIGSGPDIPWSVKGEQLLFKALTYNQWLLVG
                     RKTFDSMGVLPNRKYAVVSKNGISSSNENVLVFPSIENALKELSKVTDHVYVSGGGQI
                     YNSLIEKADIIHLSTVHVEVEGDIKFPIMPENFNLVFEQFFMSNINYTYQIWKKG"
BASE COUNT          384 a          392 c          377 g          374 t
ORIGIN      
        1 tagttgagcg gcgggcgcag cccgtccgct tgaacgccga gttaggcatc agatgccctc
       61 ggcgcgggtc gatgcacttt tcgcacatgc cgctcaacgc aagattctct caatcgttgc
      121 tttggcatat cgaacgaacg cggccgtctc ttcgacgcgc attgctaggt cgtcgtcctc
      181 gctacccagg tacgccgcgc gtgccttgca gatgaggggc cgatgctcgg caggcaaacg
      241 ctccgatacc catgcggcag caacgtcctt aggagcaatg agaccagttg aagcgctgta
      301 ccaaatgcga gcaagagcaa gaacgacgtt ccgctcgtca cccttccaat ccgactctgc
      361 attccactgg gcaatagtgt cgaaaagcgc cttggagaaa tgctccttcg gcaccggctc
      421 gaaaaacgtg gctgcggatg ggcctagaag cgcaaggctg tgttgcctcg ccttggtcag
      481 caaaatcgca agatcgtgat ccagaacggc aggctcgaac gttccggaaa ggatgtcgtg
      541 gcggagccac tcaccgaact gaagctcacg ccgcgccgga tagcgccaag gcactacttc
      601 gcttcgagcg acaacagtta gctccagcgg tcgccatgtt ccgccatcgc ctggcggtga
      661 tgagactttc agcaaatcga gcattagcgc ctgccggagc gaatcgttag gtgcggcgct
      721 gacggtcacg agcaagtcta tgtcgctgtc cggcttcagc cctccatcga tcgcagatcc
      781 gaacaggtgg attgtgtcca gtgtcgcagc cagatggcgc tcgatcaccg cgcgagcgtg
      841 ggacagctgc ttgaaaactt gtgcagggaa aaattcaccc atgatgccta acgttaagtt
      901 cagcggcagc ttttaagttg cggctttgtg gaatactttt gcgcagcaaa accacaaaga
      961 cgcgacttaa aagctgtcca aggagcgaag cgactggtgc tgcaacgcat tgttagcctt
     1021 ttttccaaat ctggtatgta taatttatat tagacataaa aaactgttca aaaaccaaat
     1081 tgaaattctc aggcattata gggaatttga tatcaccttc gacttcaacg tgaacagtag
     1141 acaaatgaat tatatctgct ttttcaataa ggctattata gatttgaccc ccgccagaga
     1201 catatacatg atctgtaact tttgatagct ctttcaaagc attttctatt gaaggaaaaa
     1261 ctaggacgtt ttcatttgag cttgaaattc cgttctttga cactactgca tatttgcgat
     1321 ttggaagaac acccatagag tcaaatgttt ttcttccgac aaggagccat tgattatatg
     1381 tgagcgcttt aaagagtagt tgctcacctt ttactgacca cgggatatca ggaccactac
     1441 cgattacgcc attttctgac actgcagaaa tcaatgatat tttcaattta actcccttaa
     1501 tggctaactt tgttttaggg cgactgc
//
LOCUS       DACAOP010000246         1519 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.252, whole genome shotgun sequence.
ACCESSION   DACAOP010000246 DACAOP010000000
VERSION     DACAOP010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.252"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(1..187)
                     /locus_tag="IT892_004622"
                     /pseudo
     CDS             complement(1..187)
                     /locus_tag="IT892_004622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308269.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
     gene            complement(218..544)
                     /locus_tag="IT892_004623"
     CDS             complement(218..544)
                     /locus_tag="IT892_004623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137726.1"
                     /translation="MKYIIFLFRAIWLALSLLILFFSMHRLSLLDSTRDVSELISLMS
                     YGMMVICFPTGIVFFIALIFIGTVSDIIGVRIDSKYIMAIIIWLYFLSGGYIQWFVLS
                     KRIINK"
     gene            complement(544..1341)
                     /locus_tag="IT892_004624"
     CDS             complement(544..1341)
                     /locus_tag="IT892_004624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HAP3137727.1"
                     /translation="MDPVYTPARKIHLYHCDHRGLPLALISTEGTTAWYAEYDEWGNL
                     LNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNFYQY
                     PLNPISNIDPLGLETLKCIKPLHSMGGTGERSGPDIWGNPFYHQYLCVPDGKGDYTCG
                     GQDQRGESKGDGLWGPGKASNDTKEAAGRCDLVETDNSCVENCLKGKFKEVRPRYSVL
                     PDIFTPINLGLFKNCQDWSNDSLETCKMKCSGNNIGRFIRFVFTGVM"
BASE COUNT          396 a          394 c          317 g          412 t
ORIGIN      
        1 ccccttccgg gatgaggtcg gttttctccg tcagcctgcc gtgacggtca taccggtaaa
       61 gatagtgcgc gtcacgggcg atacggttat ccggccacat gctgagggtg ctgtccgggt
      121 gcagctccgg gtcgggcagg cggttacctg ccgggtctgt ggcatacggg atatcaatgc
      181 ccaggttaca tataataata agagcaatta acttaattta tttgtttata atgcgcttac
      241 ttaatacaaa ccattgaata taccctcctg acagaaaata aagccatatt attatcgcca
      301 taatatactt actatcaatc cttacgccaa taatgtctga tacagtccct ataaatatta
      361 gagcaataaa gaatactatg cctgttggaa aacatattac catcattcca taagacatga
      421 gactaattaa ctcgctcaca tcacgagtgg agtctaatag tgaaagtcta tgcatggaaa
      481 agaatagtat taaaagcgat aaagccagcc atatagctct gaataaaaaa ataatatatt
      541 tcattacatc actccggtga atacaaatct aataaaacgt ccaatgttat ttccggagca
      601 cttcatctta catgtttcta aagaatcatt agaccagtct tggcagtttt taaatagccc
      661 taaatttata ggtgtaaata tatcaggcaa tacagaataa cgcggcctta cctctttaaa
      721 cttccctttt aaacagttct ccacacaact attatcggtt tcaacgaggt cacaacggcc
      781 agcagcttct tttgtatcat tacttgcttt acctggcccc catagaccat ctccttttga
      841 ttctccccgt tggtcttggc caccacaagt atagtcccct ttaccatctg ggacacaaag
      901 atattgatga tagaacggat tcccccatat atctggaccg cttctttcac cagttccgcc
      961 cattgaatgc agtggcttaa tgcattttag tgtttctaat cctaatggat ctatatttga
     1021 gatcggattc aacggatact gataaaaatt ccatccccct ttcagcccaa tcggatcctg
     1081 agtgatatat cgcccctgca gcgggtcata atagcggtgg cggttgtaat acaggccgga
     1141 ctcctcatca tactgctgcc ccggcaggcg gataagctgc tgcagctgat gcgggttctc
     1201 ttcattcagc aggttacccc attcatcgta ttctgcgtac cacgctgttg tcccttccgt
     1261 gctgataagg gccagcggca ggccgcgatg gtcgcagtgg tacaggtgaa tttttcgcgc
     1321 cggcgtgtat accgggtcca tctggctttg catctgcgcc accgtcaggc cgcacgatgc
     1381 cagccagcgg cggctttcct cactcacccg gtcagccagg atttcacttt ccagccggtc
     1441 gagcatctgc accagcaccg gcgggaacac cacactgcca ccgtcttcgc cgccggactg
     1501 ctgaagggta tccgccagg
//
LOCUS       DACAOP010000247         1491 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.254, whole genome shotgun sequence.
ACCESSION   DACAOP010000247 DACAOP010000000
VERSION     DACAOP010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1491
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.254"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..637)
                     /locus_tag="IT892_004625"
     CDS             complement(<1..637)
                     /locus_tag="IT892_004625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137728.1"
                     /translation="MSPVSSIGNDISSDLARRKMNDLPESPIGNNLEALAPGIEKLKQ
                     TSIEMVTLLNALQPGGKCIITGDFQKELAYLQNVILYNDSSLRMDFFGYNARIIQRSD
                     NTCELTINEPLKNQEISTGNINVNCPLKDIYNEIRRLNVIFSCGTGGIVDLSSLDLRN
                     VDLELYDFTDKHMANTILNPFKLDDTDFTNANMFQVNFVSSKQNATISWDYL"
     gene            complement(659..1198)
                     /locus_tag="IT892_004626"
     CDS             complement(659..1198)
                     /locus_tag="IT892_004626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312027.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137729.1"
                     /translation="MKGFPIAHIFHPSIPPMHAVVNNHNRNIDYWTVKRKFAEIVSTN
                     DVNKIYSISNELRRVLSAITALNFYQGDVPSVMIRIQPENMSPFIIDISTGEHDDYII
                     QTLDVGTFAPFGEQCTCSAVNKKELECIKETISKYCAKFTRKEAILTPPTYFNKTAIP
                     SDCWQILFFSPDHFNNDFY"
BASE COUNT          450 a          270 c          281 g          490 t
ORIGIN      
        1 gtaaataatc ccatgagatt gtggcgtttt gttttgaact aacgaaattt acctgaaaca
       61 tgttggcatt agtaaaatct gtgtcatcca atttaaaagg atttaaaatt gtattggcca
      121 tatgtttatc tgtaaaatca taaagttcta aatcgacatt ccgtaagtcc agagaggata
      181 gatcaactat acctccagtc ccacaactaa agattacgtt caacctcctg atttcattgt
      241 aaatgtcttt caatgggcaa ttaacattga tattgcctgt ggatatttcc tggtttttta
      301 acggttcatt aattgtaagt tcacaggtat tgtctgatcg ttgaataatt cgggcgttat
      361 aaccaaaaaa atccatacga agagaggagt cattataaag aattacattt tgtaagtacg
      421 ctaattcttt ttgaaaatca ccagtgataa tgcatttccc acctggttgt aacgcgttaa
      481 gtaaagtgac catttcaata gaggtctgtt ttagtttttc tatgcctggt gctagtgctt
      541 cgaggttatt tcctatgggg ctttcaggaa ggtcattcat ttttcgacgg gctaaatcac
      601 tactaatatc attaccaatt gatgaaacag gggacattat tttatccttc ataaataatc
      661 aataaaaatc attattaaaa tgatcgggtg aaaaaaagag aatttgccaa caatctgaag
      721 gaatggcggt tttattaaag tacgtagggg gggttaagat ggcttctttt cgggtgaatt
      781 ttgcacaata cttagaaatc gtctccttaa tacactccag ctctttttta ttgacggctg
      841 agcaagtaca ttgttcgcca aaaggtgcaa aagtgcctac atctaatgtt tgtatgatat
      901 aatcgtcatg ttctcctgta gaaatatcta tgatgaatgg actcatattt tccggttgga
      961 ttcgaatcat gacagaagga acatcgcctt gatagaagtt caatgcagta attgcagata
     1021 atactctccg cagttcatta cttatactgt atattttatt aacgtcattg gtggagacaa
     1081 tttctgcaaa ctttcttttt accgtccaat aatcaatatt tctgttgtga ttgttaacca
     1141 ctgcgtgcat tggcgggatt gaagggtgaa aaatatgtgc aattgggaag cctttcattg
     1201 atgcctgcct tgtcatcatg acaaacaata atagatgctt attttcctcg cacggcactt
     1261 tcgcactatc aaaaaacgct catttacccg gcattacagt aaacgaagca acattctgtg
     1321 gcctacgccg atcaaaagct ctgtgaaaat tccccttgtt gtctttggct gaccttatcg
     1381 cggcgaccag caattattcg ttttgtgatc ctcaacacaa aatgctattc gtcacctatg
     1441 aggggagaag aatttatgga aaacgattgc attcacaaaa tgacgtcctg t
//
LOCUS       DACAOP010000248         1482 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.255, whole genome shotgun sequence.
ACCESSION   DACAOP010000248 DACAOP010000000
VERSION     DACAOP010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1482
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.255"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            181..1392
                     /gene="bluF"
                     /locus_tag="IT892_004627"
     CDS             181..1392
                     /gene="bluF"
                     /locus_tag="IT892_004627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blue light-responsive regulator BluF"
                     /protein_id="HAP3137730.1"
                     /translation="MLTTLIYRSHIRDDEPVKKIEEMVSIANRRNMQSDVTGILLFNG
                     SHFFQLLEGPEEQVKMIYRAICQDPRHYNIVELLCDYAPARRFGKAGMELFDLRLHER
                     DDVLQAVFDKGTSKFQLTYDDRALQFFRTFVLATEQSTYFEIPAEDSWLFIADGSDKE
                     LDSCALSPTINDHFAFHPIVDPLSRRIIAFEAIVQKNEDSPSAIAVGQRKDGEIYTAD
                     LKSKALAFTMAHALELGDKMISINLLPMTLVNEPDAVSFLLNEIKANALVPEQIIVEF
                     TESEVISRFDEFAEAIKSLKAAGISVAIDHFGAGFAGLLLLSRFQPDRIKISQELITN
                     VHKSGPRQAIIQAIIKCCTSLEIQVSAMGVATPEEWMWLESAGIEMFQGDLFAKAKLN
                     GIPSIAWPEKK"
BASE COUNT          435 a          307 c          303 g          437 t
ORIGIN      
        1 taaaacatat tgcatcattt aactgacaat ctatacaaga tttttcgcca actagtgttc
       61 aactttttcc attttttatc aatgtaaaga aacggttatg ttttggtatt aaaagaaaga
      121 cacaagaaga tatgtctgtt accgtcttac tctcgcctca cccattaccc tggattgtta
      181 atgcttacca cccttattta tcgtagccat atacgtgacg acgaacctgt caaaaaaatc
      241 gaagaaatgg tttcgatagc aaatcgcagg aacatgcagt ctgacgtaac agggatctta
      301 ctgtttaatg gttctcattt tttccagctt ctggaaggtc cggaagaaca ggttaaaatg
      361 atatatcggg ctatatgcca ggatccacgg cactataata ttgttgagct gctgtgcgat
      421 tacgcgcctg ctcgccgttt tggcaaagcg ggaatggaat tatttgattt gcgcctgcac
      481 gagcgagatg acgttttaca ggccgtattc gacaaaggca catcaaaatt tcagctaact
      541 tatgatgaca gagcgctaca attttttcgt acttttgtcc ttgcaaccga acaatcaacc
      601 tatttcgaga tccctgccga agactcctgg ctttttatcg ctgacggatc tgataaagaa
      661 cttgattcct gtgccctttc accaactata aacgaccact ttgcctttca tcctattgtc
      721 gatcccttat cgcggcggat aatcgctttt gaagccattg tgcaaaaaaa tgaagatagc
      781 ccatcagcca tagcggttgg gcagcgtaaa gacggggaaa tctacacagc ggatctcaaa
      841 agtaaggcgc ttgcattcac gatggcacac gcacttgagc tcggtgataa aatgatttca
      901 atcaatctat tacctatgac cctggttaac gaacctgacg cagtctcttt tttacttaat
      961 gaaataaagg ccaatgctct ggtgcctgaa caaatcatcg ttgaatttac tgaaagtgaa
     1021 gtcatatctc ggtttgatga gtttgccgaa gcgattaaat cgctaaaggc tgctggtatc
     1081 agtgtagcaa ttgatcattt tggcgcaggt tttgctggtt tgttactcct gtcacgcttc
     1141 cagcctgaca gaattaaaat cagtcaggaa ttgattacca atgttcataa aagtgggcca
     1201 cggcaggcaa ttattcaggc gatcataaaa tgctgtacat cacttgaaat tcaagtcagt
     1261 gctatgggcg tggcaacacc agaagagtgg atgtggcttg aatccgcagg aattgagatg
     1321 tttcagggag atctgtttgc taaagctaaa ttgaatggta tcccttccat agcgtggcca
     1381 gagaaaaaat aattttcagc acattctttc acatgatttc agtaaatcat cgtgaaaatg
     1441 aatacgttac gtttaaattt aatccacatt aaaaataatg tt
//
LOCUS       DACAOP010000249         1464 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.256, whole genome shotgun sequence.
ACCESSION   DACAOP010000249 DACAOP010000000
VERSION     DACAOP010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1464
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.256"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..287
                     /locus_tag="IT892_004628"
     CDS             <1..287
                     /locus_tag="IT892_004628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HAP3137731.1"
                     /translation="NYIKEAKYDMAVGHLLLKSFWANEAVFQMMMLSYNLFLLFKFDS
                     LDSSEYRQQIKTFRLKYVFLAAKIIKTARYVIMKLSENYPYKGVYEKCLV"
     gene            complement(435..557)
                     /locus_tag="IT892_004629"
     CDS             complement(435..557)
                     /locus_tag="IT892_004629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137732.1"
                     /translation="MHSLCHHLKLPIRSIRVTSVFPKFHVCFLLASKITISRRI"
     gene            537..1412
                     /locus_tag="IT892_004630"
     CDS             537..1412
                     /locus_tag="IT892_004630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A extended-spectrum beta-lactamase
                     CTX-M-14"
                     /protein_id="HAP3137733.1"
                     /translation="MVTKRVQRMMFAAAACIPLLLGSAPLYAQTSAVQQKLAALEKSS
                     GGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKP
                     ADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGD
                     ETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNT
                     TGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESR
                     RDVLASAARIIAEGL"
BASE COUNT          394 a          322 c          411 g          337 t
ORIGIN      
        1 aaaactatat caaagaagcc aaatacgaca tggcggtggg tcatctcttg ctaaagtcat
       61 tttgggcgaa tgaagccgtg tttcaaatga tgatgctttc atataaccta tttttgttgt
      121 tcaagtttga ttccttggac tcttcagaat acagacagca aataaagacc tttcgtttga
      181 agtatgtatt tcttgcagca aaaataatca aaaccgcaag atatgtaatc atgaagttgt
      241 cggaaaacta tccgtacaag ggagtgtatg aaaaatgtct ggtataataa gaatatcatc
      301 aataaaattg agtgttgctc tgtggataac ttgcagagtt tattaagtat cattgcagca
      361 aagatgaaat caatgattta tcaaaaatga ttgaaaggtg gttgtaaata atgttacaat
      421 gtgtgagaag cagtctaaat tcttcgtgaa atagtgattt ttgaagctaa taaaaaacac
      481 acgtggaatt tagggaatac tgatgtaaca cggattgacc gtattgggag tttgagatgg
      541 tgacaaagag agtgcaacgg atgatgttcg cggcggcggc gtgcattccg ctgctgctgg
      601 gcagcgcgcc gctttatgcg cagacgagtg cggtgcagca aaagctggcg gcgctggaga
      661 aaagcagcgg agggcggctg ggcgtcgcgc tcatcgatac cgcagataat acgcaggtgc
      721 tttatcgcgg tgatgaacgc tttccaatgt gcagtaccag taaagttatg gcggccgcgg
      781 cggtgcttaa gcagagtgaa acgcaaaagc agctgcttaa tcagcctgtc gagatcaagc
      841 ctgccgatct ggttaactac aatccgattg ccgaaaaaca cgtcaacggc acaatgacgc
      901 tggcagaact gagcgcggcc gcgttgcagt acagcgacaa taccgccatg aacaaattga
      961 ttgcccagct cggtggcccg ggaggcgtga cggcttttgc ccgcgcgatc ggcgatgaga
     1021 cgtttcgtct ggatcgcact gaacctacgc tgaataccgc cattcccggc gacccgagag
     1081 acaccaccac gccgcgggcg atggcgcaga cgttgcgtca gcttacgctg ggtcatgcgc
     1141 tgggcgaaac ccagcgggcg cagttggtga cgtggctcaa aggcaatacg accggcgcag
     1201 ccagcattcg ggccggctta ccgacgtcgt ggactgtggg tgataagacc ggcagcggcg
     1261 actacggcac caccaatgat attgcggtga tctggccgca gggtcgtgcg ccgctggttc
     1321 tggtgaccta ttttacccag ccgcaacaga acgcagagag ccgccgcgat gtgctggctt
     1381 cagcggcgag aatcatcgcc gaagggctgt aactggtttt gttgaataaa tcgaactttt
     1441 gctgagttga aggatcagat cacg
//
LOCUS       DACAOP010000250         1456 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.257, whole genome shotgun sequence.
ACCESSION   DACAOP010000250 DACAOP010000000
VERSION     DACAOP010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.257"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(131..1117)
                     /locus_tag="IT892_004631"
     CDS             complement(131..1117)
                     /locus_tag="IT892_004631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137734.1"
                     /translation="MIPDYLTFIRFQDKRNLIYIYAIGLILIGFYWKNAGFTFPSEDI
                     GVVSGILALVLYNFIFDLKAYWAYKCVTKNIDFSWFKKKQNHKIELFLTQPLVAGFLS
                     LIMLSAMSWGLYQLLPSLYALFLISLLGPLVIFLLFRMIRTSYVKQVAISVAKKVKYK
                     SLTRYVLLSVCISTVVNLLTISPLRNSDSFVTEGQWLTFKSIIALLILCGVVLAINLF
                     FLRFSKRYAFLGRLFLQEIDLFFSSENALSTFFAKPLWLRLFILLVIEVMWITLVSVL
                     ATLVEWRIWFEAYFLLCYVPCLIYYFFYCRFLWHNDFMMACDMYFRWGHFNK"
     gene            complement(1114..1437)
                     /locus_tag="IT892_004632"
     CDS             complement(1114..1437)
                     /locus_tag="IT892_004632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP3137735.1"
                     /translation="MEDGVQAMRDYLAGLDIASPEHQVLMNVTAKSEVAPSIIKENLS
                     LHLTHTVKWTESLDTFLNMPTPVAFLEISNKPYLGNMLNDFAGVDQQRVMHCRKAFSD
                     AKVFK"
BASE COUNT          497 a          341 c          269 g          349 t
ORIGIN      
        1 gcccccgccc acgtctgtta gggcgagggg aaatcgtgca catcaactgt ctggttactc
       61 agtcaacaat caaaatgcgc aagagagtac agaacatata tgtattatct ggtcacttcc
      121 tatcacttcc tcacttatta aaatgccccc aacggaaata catgtcacat gccatcataa
      181 aatcgttatg ccagaggaat cgacaataga aaaaatagta aattaagcac ggtacatagc
      241 agagtaaaaa ataggcttca aaccaaatcc gccattctac aagcgttgcc aataccgaca
      301 ccagcgtaat ccacatcact tcaataacca gcaatatgaa taaccgaagc caaagcggct
      361 tggcaaaaaa ggtcgacaac gcattttcac tggagaaaaa cagatcgatt tcctgcaaaa
      421 aaagcctgcc cagaaaagcg taccgcttgg agaagcgcag aaaaaacaga ttaatcgcca
      481 acactacgcc acaaagaatg agcaatgcaa ttatcgattt aaacgttaac cactgcccct
      541 ctgtcacaaa agaatcactg ttacgcaacg ggctgatagt aagcaggtta acaaccgttg
      601 agatgcacac cgaaagcagc acatagcgag tcagactttt atattttact tttttcgcta
      661 ctgaaatagc gacctgcttg acataactgg tgcggatcat ccgaaacagc agaaagatga
      721 ccaacggccc aagtaacgaa atcaggaaca gcgcatataa cgagggtaga agctggtata
      781 gcccccaact cattgcactc aacatgatta acgacagaaa tcctgccacc agaggttgtg
      841 taagaaataa ttctattttg tggttctgct ttttcttaaa ccacgaaaaa tcgatattct
      901 tcgtgacgca tttataagcc cagtacgcct tgagatcaaa aataaaatta tacagcacca
      961 gagccagaat cccactaact acaccaatat cctctgatgg aaaagtaaac cctgcattct
     1021 tccaataaaa gcctatcaga ataagtccaa tagcataaat gtatatcaga tttcgtttat
     1081 cctgaaagcg aataaaagtt aaataatcag gaatcatttg aatacctttg catcactaaa
     1141 tgctttacga caatgcataa ctcgttgctg atccacgcca gcaaaatcat ttaacatatt
     1201 ccccaaatag ggcttattac ttatttcaag gaaagctacc ggggttggca tattcagaaa
     1261 tgtatcgaga gattcagtcc atttcaccgt atgagttaag tgtaatgaga gattttcttt
     1321 gataattgac ggagcgacct cgctttttgc tgttacgttc atcagaacct gatgctctgg
     1381 cgaagcgata tccagtccgg caagataatc gcgcattgcc tgaacgccgt cttccatcaa
     1441 acgcgtgtgc caggca
//
LOCUS       DACAOP010000251         1445 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.258, whole genome shotgun sequence.
ACCESSION   DACAOP010000251 DACAOP010000000
VERSION     DACAOP010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1445
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.258"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..550
                     /locus_tag="IT892_004633"
     CDS             <1..550
                     /locus_tag="IT892_004633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HAP3137736.1"
                     /translation="ITQDPIGLKGGWNFYQYPLNPVQYIDSMGLASKYGHLNNGGYGA
                     RPNKPPTPDPSKLPDIAKQLRLPYPIDQASSAPNVFKTFFRALSPYDYTLYCRKWVKP
                     NLTCTPQDDSQYPGMDTKTASDYLPQTNWPTTQLPPGYTCAEPYLFPDINKPDGPATA
                     GIDDLGEILAKMKQRTSRGIRK"
     gene            547..1116
                     /locus_tag="IT892_004634"
     CDS             547..1116
                     /locus_tag="IT892_004634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137737.1"
                     /translation="MKRVLFFLLMIFVSFGVIADCEIQAKDHDCFTIFAKGTIFSAFP
                     VLNNKAMWRWYQNEDIGEYYWQTELGTCKNNKFTPSGARLLIRVGSLRLNENHAIKGT
                     LQELINTAEKTAFLGDRFRSYIRAGIYQKKSSDPVQLLAVLDNSIMVKYFKDEKPTYA
                     RMTAHLPNKNESYECLIKIQHELIRSEEK"
     gene            1342..>1445
                     /locus_tag="IT892_004635"
     CDS             1342..>1445
                     /locus_tag="IT892_004635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP3137738.1"
                     /translation="MELKKLMEHISITPDYRQAWKVVHKLSDILLLTI"
BASE COUNT          494 a          255 c          292 g          404 t
ORIGIN      
        1 tatcactcag gatccgattg ggctgaaggg gggatggaat ttttatcagt atccgctgaa
       61 tccggttcag tatatagatt caatgggact ggcatcaaaa tatggacact taaataatgg
      121 cggatatgga gcgagaccca acaaaccgcc tacgcccgat ccaagtaaat tgccggacat
      181 agcgaaacaa ttaagactgc catatcctat tgaccaggcc agtagtgcgc ctaatgtttt
      241 caaaacattc ttcagagcat taagccctta cgactacaca ctgtattgca ggaagtgggt
      301 aaaaccaaat ctgacttgta cgccacagga tgattcccag tatccaggga tggatacaaa
      361 gacagcaagt gattacctgc cacagacaaa ttggccaaca actcaattac caccaggata
      421 tacttgtgca gaaccctatt tattcccaga cattaataaa cccgatgggc cagcaacagc
      481 agggatagat gatttgggtg aaattttagc taagatgaaa cagagaacat cgagaggaat
      541 aagaaaatga aaagagtttt gttctttttg ctgatgatat ttgttagttt tggtgttata
      601 gctgattgcg aaatacaagc taaagatcat gattgtttta ctattttcgc taagggtact
      661 attttttccg cgtttcctgt cttaaataat aaagccatgt ggagatggta tcagaatgag
      721 gacatcggtg agtattattg gcaaacagaa ctgggtacat gtaaaaataa taaattcaca
      781 ccaagcgggg cgagactctt aattcgcgtc gggtcactac gccttaatga aaatcatgcc
      841 atcaaaggaa cgttgcagga gttgataaat acagcagaaa aaacggcgtt tctcggcgat
      901 cggtttagaa gttatataag agcgggtatc tatcaaaaaa agagcagtga tccagttcag
      961 ttgttggcag tccttgataa ttcaatcatg gtaaaatatt ttaaagatga gaaaccaact
     1021 tatgctcgaa tgacagcaca tctcccgaac aaaaatgagt cttacgaatg tttaataaag
     1081 atacagcatg aactaattcg tagtgaagag aaataaaatc tcttcctgag aaaacaaatt
     1141 aatcattgtg aaaaattata taactcatgg aataggtgtt tattttgcgt tccatttgca
     1201 gggaaagatc acgtaacgct acttttttgt actaaataat tcgaatttta agttcaacaa
     1261 ttgagatact acttattgtc taaagctgtt tttcatagct tatacatgat caaatactcc
     1321 ttacataaat aaggtgaaca aatggaactt aaaaaattga tggaacatat ttctattaca
     1381 cccgattaca gacaagcctg gaaagtggtg cataaattgt cagatattct actgttgact
     1441 atttg
//
LOCUS       DACAOP010000252         1435 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.259, whole genome shotgun sequence.
ACCESSION   DACAOP010000252 DACAOP010000000
VERSION     DACAOP010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1435
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.259"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..1364
                     /gene="ltrA"
                     /locus_tag="IT892_004636"
     CDS             <1..1364
                     /gene="ltrA"
                     /locus_tag="IT892_004636"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP3137739.1"
                     /translation="GVNKTMLQARLAVELQILRDELLSGHYQPLPARRVYIPKSNGKL
                     RPLGIPALRDRIVQRAMLMAMEPIWESDFHTLSYGFRPERSVHHAIRTVKLQLTDCGE
                     TRGRWVIEGDLSSYFDTVHHRLLMKAVRRRISDARFMTLLWKTIKAGHIDVGLFRAAS
                     EGVPQGGVISPLLSNIMLNEFDQYLHERYLSGKARKDRWYWNNSIQRGRSTAVRENWQ
                     WKPAVAYCRYADDFVLIVKGTKAQAEAIREECRGVLEGSLKLRLNMDKTKITHVNDGF
                     IFLGHRIIRKRSRYGEMRVVSTIPQEKARNFAASLTALLSGNYSESKVDMAEQLNRKL
                     KGWAMFYQFVDFKAKVFSYIDRVVFWKLAHWLARKYRTGIASLMRWWCKSPKPGQSKT
                     WVLFGKTNHGKLSGEILYRLVGQGKKLFRWRLPEGNPYLRTETRNTYTSRFTEVAMAF
                     ASI"
BASE COUNT          370 a          350 c          414 g          301 t
ORIGIN      
        1 atggcgtgaa caaaacaatg ctacaggcca gactggctgt tgagctgcaa atcctcaggg
       61 atgaattact ctcaggccac taccagccct tgcccgccag acgggtttac atccctaaaa
      121 gcaacggcaa actgcgacca ctgggtatcc ccgcgttgcg ggatcgtatt gttcagcggg
      181 ccatgctgat ggcgatggag ccgatatggg agagtgattt tcatacgctc tcatatggct
      241 tccggcctga gcgcagtgtc caccacgcga tccgcacggt gaaattacag ctcacagact
      301 gtggtgaaac ccggggacgc tgggtgattg aaggcgacct gtccagttac ttcgacaccg
      361 tacatcatcg actgctgatg aaggctgtac gccgcaggat cagtgacgca cgtttcatga
      421 ctctgctgtg gaaaaccatc aaggcgggac atatcgatgt cggtctcttt cgggcggcca
      481 gtgaaggtgt gccacagggc ggtgttatat cgccgctatt atcgaacatc atgctgaatg
      541 agttcgatca atacctgcat gagcgctacc tgagcgggaa agccagaaaa gatcggtggt
      601 actggaataa cagtatccaa cggggccgaa gtacggcggt cagagaaaac tggcagtgga
      661 aacccgcggt ggcgtactgc cgctatgccg atgattttgt cctcatcgtc aaaggcacca
      721 aagcacaggc ggaagccatc agggaggagt gtcggggtgt gctcgaaggc agtctgaaac
      781 tcaggctgaa catggataag actaaaatca cccatgttaa tgacggcttt atctttctgg
      841 ggcacaggat cattcgcaaa cgcagtcgtt atggcgagat gcgagtggtc tcaacgatcc
      901 cgcaggagaa agccagaaac ttcgccgcat cgctgacagc actgttatca ggcaactaca
      961 gtgaaagcaa agtcgatatg gctgaacaac tcaaccgaaa actgaaaggc tgggccatgt
     1021 tctatcagtt cgttgatttt aaggccaaag tcttcagtta tatcgaccgt gtcgtgttct
     1081 ggaagctggc tcactggctg gcccgcaaat accgtacagg tatcgcttcc ctgatgaggt
     1141 ggtggtgtaa atcaccgaaa ccgggtcaga gcaaaacgtg ggttttattt ggtaaaacca
     1201 atcacggcaa gctcagcggc gaaatactgt accggttggt ggggcaaggc aagaagctgt
     1261 tccgctggcg gctacccgaa ggtaatccct atctgaggac ggagaccaga aacacgtata
     1321 catcgcgctt tacagaagtg gcaatggcgt tcgccagcat ttaaatggag agccggatgc
     1381 gctgaaaggt gcacgtccgg ttcggggagg agaggcaggg aaatagtccg actac
//
LOCUS       DACAOP010000253         1403 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.260, whole genome shotgun sequence.
ACCESSION   DACAOP010000253 DACAOP010000000
VERSION     DACAOP010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1403
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.260"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            36..566
                     /locus_tag="IT892_004637"
     CDS             36..566
                     /locus_tag="IT892_004637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4329 domain-containing protein"
                     /protein_id="HAP3137740.1"
                     /translation="MNPISDIDPLGLSMWEDAKSGACTNGLCGTLSAMIGPDKFDSID
                     STAYDALNKINSQSICEDKEFAGLICKDNSGRYFSTAPNRGERKGSYPFNSPCPNGTE
                     KVSAYHTHGADSHGEYWDEIFSGKDEKIVKSKDNNIKSFYLGTPSGNFKAIDNHGKEI
                     TNRKGLPNVCRVHGNM"
     gene            538..921
                     /gene="yhhH"
                     /locus_tag="IT892_004638"
     CDS             538..921
                     /gene="yhhH"
                     /locus_tag="IT892_004638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417940.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YhhH"
                     /protein_id="HAP3137741.1"
                     /translation="MSAEFMVICKKILFRNCVIVSLFVFTYNTWAQCNNNIKIMRKYE
                     SEGKYTVRNLVKNKAIALELAEIYVKNRYGQDAAEEEKPYEITELTTSWVVEGTIHSD
                     QIAGGVFIIEIGKNDGRILNFGHGK"
     gene            1011..1271
                     /locus_tag="IT892_004639"
     CDS             1011..1271
                     /locus_tag="IT892_004639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001334888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137742.1"
                     /translation="MEVPAMSNTYQKRKASKEYGLYNKCKKLNDDELFRLLDDRNSLK
                     RISSARVLQLRGGQDAVRLAIEFCTDKNYIRRDIGAFILGQI"
BASE COUNT          507 a          200 c          312 g          384 t
ORIGIN      
        1 gactgaaggg gggatggaac ctgtatggat atcaattgaa tccgatatca gacatcgacc
       61 ccctgggttt atctatgtgg gaggatgcaa aatcgggggc atgtactaat ggtctttgcg
      121 gcacactatc cgctatgata ggtccagata aatttgattc tatagatagc accgcatatg
      181 acgccttaaa taaaataaat agccaatcta tttgcgaaga taaagagttc gctggtttaa
      241 tatgtaagga taatagtggc agatatttct caacagcacc taaccgagga gaaagaaaag
      301 gatcatatcc attcaatagc ccttgcccta atggtactga gaaagtatca gcttatcata
      361 ctcatggtgc agatagtcat ggagaatatt gggacgaaat attttcaggt aaagatgaga
      421 aaatagttaa aagtaaagat aacaatatca agtcatttta tttaggtacg cccagtggta
      481 attttaaagc aatagataac cacgggaagg aaataacaaa cagaaaagga ttacctaatg
      541 tctgcagagt tcatggtaat atgtaaaaaa atattgttta ggaactgtgt cattgtatct
      601 ttgtttgttt ttacatacaa cacatgggcg cagtgtaata ataatattaa aataatgcgc
      661 aagtatgaaa gtgaaggtaa atataccgtt agaaatttgg ttaaaaataa agctatagca
      721 ttggaattag ctgagatata tgttaagaat cgttatggac aggatgccgc agaagaagaa
      781 aaaccatacg aaatcactga gttaacaaca agttgggttg ttgaaggtac cattcactca
      841 gaccaaattg ctggtggggt ttttattata gaaataggca aaaatgatgg gagaattctg
      901 aattttggcc acggaaaata agtatgtaag gataatcaaa catcgtgtgc gctgatggca
      961 gagtaggtgg aggactccag acagtcaaac gatagaaaaa gatagccttt atggaggttc
     1021 ctgcaatgtc aaatacatac cagaaaagaa aggcaagtaa agagtatggt ttatataata
     1081 aatgtaagaa actaaatgat gatgaattat ttcgcttact tgatgatcgc aattccttga
     1141 aaaggatttc atctgccaga gtattacagt taagaggggg gcaagacgct gttagattgg
     1201 caattgaatt ctgcactgac aaaaattata tccgtagaga tatcggagca tttatactcg
     1261 ggcaaatata aatttgcaaa aaatgcgaag ataatgtttt taatattttg aacaatatgg
     1321 cattgaatga taagagtgct tgcgttcgag ctacggcaat cgagtcaacg gccagggaaa
     1381 gatcatcaaa agttcacttt ttg
//
LOCUS       DACAOP010000254         1357 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.261, whole genome shotgun sequence.
ACCESSION   DACAOP010000254 DACAOP010000000
VERSION     DACAOP010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1357
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.261"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>1357
                     /locus_tag="IT892_004640"
     rRNA            <1..>1357
                     /locus_tag="IT892_004640"
                     /product="23S ribosomal RNA"
BASE COUNT          370 a          292 c          432 g          263 t
ORIGIN      
        1 gggacacgtg gtatcctgtc tgaatatggg gggaccatcc tccaaggcta aatactcctg
       61 actgaccgat agtgaaccag taccgtgagg gaaaggcgaa aagaaccccg gcgaggggag
      121 tgaaaaagaa cctgaaaccg tgtacgtaca agcagtggga gcacgcttag gcgtgtgact
      181 gcgtaccttt tgtataatgg gtcagcgact tatattctgt agcaaggtta accgaatagg
      241 ggagccgaag ggaaaccgag tcttaactgg gcgttaagtt gcagggtata gacccgaaac
      301 ccggtgatct agccatgggc aggttgaagg ttgggtaaca ctaactggag gaccgaaccg
      361 actaatgttg aaaaattagc ggatgacttg tggctggggg tgaaaggcca atcaaaccgg
      421 gagatagctg gttctccccg aaagctattt aggtagcgcc tcgtgaattc atctccgggg
      481 gtagagcact gtttcggcaa gggggtcatc ccgacttacc aacccgatgc aaactgcgaa
      541 taccggagaa tgttatcacg ggagacacac ggcgggtgct aacgtccgtc gtgaagaggg
      601 aaacaaccca gaccgccagc taaggtccca aagtcatggt taagtgggaa acgatgtggg
      661 aaggcccaga cagccaggat gttggcttag aagcagccat catttaaaga aagcgtaata
      721 gctcactggt cgagtcggcc tgcgcggaag atgtaacggg gctaaaccat gcaccgaagc
      781 tgcggcagcg acgcttatgc gttgttgggt aggggagcgt tctgtaagcc tgtgaaggtg
      841 tgctgtgagg catgctggag gtatcagaag tgcgaatgct gacataagta acgataaagc
      901 gggtgaaaag cccgctcgcc ggaagaccaa gggttcctgt ccaacgttaa tcggggcagg
      961 gtgagtcgac ccctaaggcg aggccgaaag gcgtagtcga tgggaaacag gttaatattc
     1021 ctgtacttgg tgttactgcg aaggggggac ggagaaggct atgttggccg ggcgacggtt
     1081 gtcccggttt aagcgtgtag gctggttttc caggcaaatc cggaaaatca aggctgaggc
     1141 gtgatgacga ggcactacgg tgctgaagca acaaatgccc tgcttccagg aaaagcctct
     1201 aagcatcagg taacatcaaa tcgtacccca aaccgacaca ggtggtcagg tagagaatac
     1261 caaggcgctt gagagaactc gggtgaagga actaggcaaa atggtgccgt aacttcggga
     1321 gaaggcacgc tgatatgtag gtgaagtccc tcgcgga
//
LOCUS       DACAOP010000255         1350 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.262, whole genome shotgun sequence.
ACCESSION   DACAOP010000255 DACAOP010000000
VERSION     DACAOP010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1350
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.262"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..658)
                     /locus_tag="IT892_004641"
     CDS             complement(<1..658)
                     /locus_tag="IT892_004641"
                     /inference="COORDINATES: protein motif:HMM:NF025082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP3137743.1"
                     /translation="MNKPNLTIVILTKNEQLHLRRCLDSVINFCERIVIVDSFSDDST
                     LEIIKEYPGIVELYQNKFINYANQFQWGLDNSGITTDWVMRLDADEYIESDLQDEIKN
                     KLNSIDKNKNCIFIRRKYFYKGKWIKHGAVYPLNLLRIWRNGQGRIEQRWMDEHIVVN
                     NPQPSFFKGHIVDYNLNDMKWWIEKHIKYADREVVDLLNIKYQLFNRDEDVRKQGGFQ
                     A"
     gene            complement(651..1253)
                     /locus_tag="IT892_004642"
     CDS             complement(651..1253)
                     /locus_tag="IT892_004642"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="putative colanic acid biosynthesis
                     acetyltransferase"
                     /protein_id="HAP3137744.1"
                     /translation="MMSTIVIPKMQKIDYIAKEENLSGEYEINYFSFKNKLHRLIWGG
                     VYIIFFKYSPVPMFGYRNFILSLFGARLGKNVRIYPSAKIWMPRNLTIGNNSSIGPRA
                     LIYNQGSIYIGNDSIISQDVTICASTHDYNKRDHPLILKNVEIGNRVWLCAESFVGPG
                     VQVFDGAVLGARAVAKRNLSSWSVYDGNPCNKLKERVNNE"
BASE COUNT          433 a          271 c          176 g          470 t
ORIGIN      
        1 tagcctggaa accaccttgc ttccttacat cctcatcacg attaaataat tgatatttaa
       61 tgtttaataa atcaacaact tctctgtctg catattttat atgtttttct atccaccact
      121 tcatatcatt taaattataa tccacaatat gacctttaaa aaatgaaggc tgtgggttat
      181 tgacaactat atgttcatcc atccatcttt gttctatacg gccttgcccg ttccgccaaa
      241 tccgtaaaag atttagtgga tataccgctc catgttttat ccactttccc ttgtaaaaat
      301 acttacgcct gatgaaaatg caatttttat ttttatcaat cgaatttaat ttgtttttaa
      361 tctcatcttg aaggtcagat tcaatatatt catcagcatc aagcctcatt acccaatccg
      421 ttgttattcc cgaattatct aagccccatt gaaattggtt agcatagttg atgaatttat
      481 tttgatagag ttcaactata cccggatact cttttataat ttccaatgta ctatcatcag
      541 aaaaagagtc aacgataaca attctttcgc aaaaatttat aactgaatct aaacaacgcc
      601 ttaggtgtag ttgctcattt tttgtcaaaa taacaatagt tagattaggc ttattcatta
      661 ttcactcttt ctttaagttt attacatggg ttaccatcgt atacagacca tgaagataaa
      721 tttctcttag cgacagctct agcacctaac accgccccat caaaaacttg aactccaggg
      781 ccaacaaatg actcggcaca aagccaaact ctatttccaa tttctacatt ctttaatata
      841 aggggatgat cacgtttgtt gtaatcatgc gtgctcgcac aaatagttac atcttggcta
      901 ataattgaat cattaccgat ataaatagaa ccctgattgt aaattagtgc ccttggtcca
      961 atggaggaat tatttccaat ggttaaattt cttggcatcc atattttagc acttggatag
     1021 attctgacat ttttaccaag ccttgctcca aacaatgaaa gaataaaatt cctatatccg
     1081 aacatgggca caggagaata tttaaaaaat attatataca ccccccccca aattaagcga
     1141 tgtaatttat ttttaaagct aaagtagtta atttcatatt caccagacaa attttcctcc
     1201 tttgctatat aatcaatttt ttgcatttta ggtatcacaa ttgtactcat catgattcat
     1261 tattttatcg gatttaatag cgagcaaaga ataaaataaa aacactactg atatttctgg
     1321 tcgtaccatt gttgattcgc tcaatccgta
//
LOCUS       DACAOP010000256         1306 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.264, whole genome shotgun sequence.
ACCESSION   DACAOP010000256 DACAOP010000000
VERSION     DACAOP010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1306
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.264"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..647)
                     /locus_tag="IT892_004643"
     CDS             complement(<1..647)
                     /locus_tag="IT892_004643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000906719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137745.1"
                     /translation="MLINIENATPEKVLNNSFAIAVENILRAFAEQKHLVIGARVFFK
                     TIINDQSGLYSLSSKSYAQEALSGLTEYYAILDQVSFYVSVDFNISDKSFKWVQIGES
                     FKFVCGPLYFNDSAQLQKTKIVCENPLDSDFFKVIAAHYAEGINLSRCEMGFIALNGG
                     GGSTKDIFERAIQNNEIVFCIVDNDKKHPGAPFGGTCSHFLGSQITRSGFVEILDV"
     gene            complement(650..>1306)
                     /locus_tag="IT892_004644"
     CDS             complement(650..>1306)
                     /locus_tag="IT892_004644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000589623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3696 domain-containing protein"
                     /protein_id="HAP3137746.1"
                     /translation="KYIAPLRATSERFYRFQDLQVNEIDHTGSNLAMLLNSLRPADKS
                     KFEDWTKLNFDFIIKVEQSGSHFAILINTGENSENYNVSDMGFGYSQVLPIVTAIWLE
                     TERRATTVRKPITFIIEQPELHLHPSYQHNLASIFAKVVTKAKENNVDLKIIFETHSQ
                     TMIEALGEYIEENESLSQDDISILVFEKDDKQQTIVKKSYFDENGFLKNWPVGFFSGK
                     "
BASE COUNT          428 a          270 c          195 g          413 t
ORIGIN      
        1 acatctaaaa tctccacgaa acctgagcga gtaatttgtg agcccaaaaa atgtgagcaa
       61 gtacctccga atggggctcc aggatgtttt ttgtcattat ccacaataca aaaaactatc
      121 tcattatttt gaattgcacg ctcgaatata tccttagtac tgcccccacc gccatttaga
      181 gcgataaaac ccatttcgca gcgagataag ttaatacctt cggcataatg agccgctata
      241 accttaaaaa aatcagaatc caaaggattt tcacatacta ttttcgtttt ttgcaattgt
      301 gccgagtcat taaaatacaa tggaccacaa acaaatttaa aagattcacc gatctgaacc
      361 catttaaatg atttatcact aatattaaag tcgacagata cataaaatga gacctgatcc
      421 aagatagcat agtactctgt tagacccgac aaagcctctt gcgcgtaact ttttgatgaa
      481 aggctataaa gcccgctttg atcattgata atagttttaa aaaaaaccct tgcccctata
      541 accaagtgtt tttgttcagc gaatgcccga agtatatttt caaccgctat ggcaaatgag
      601 ttatttagca ccttctcagg tgtcgcattt tcgatattaa tcaacataac tacttacccg
      661 agaaaaagcc aaccggccaa ttttttagga aaccattctc gtcaaaataa gatttcttaa
      721 ctatagtctg ctgcttatca tctttttcaa ataccagtat tgaaatatca tcctgtgaaa
      781 gactttcatt ttcctcaata tattcaccaa gtgcttcaat catggtctgg ctatgtgtct
      841 caaaaattat cttcaaatct acattatttt cttttgcttt agttactact tttgcaaaaa
      901 tacttgctaa attatgctga tatgacggat gtaaatgcaa ttctggctgc tcaatgataa
      961 atgttatagg ttttctaacc gtggtagcac gacgttctgt ctcaagccaa atggctgtaa
     1021 ctatcggcaa aacctgagaa taaccaaacc ccatatcact aacattatag ttctcactat
     1081 tttcaccggt atttattaaa attgcaaagt gagagccact ttgttcaacc ttgataatga
     1141 aatcaaaatt taactttgtc caatcttcaa attttgattt atcagccggt cttaatgaat
     1201 tcaaaagcat tgcaagattg gaaccagtat gatctatctc attaacctgt aaatcttgaa
     1261 aacgataaaa tctttctgat gtagcacgca gtggagctat gtactt
//
LOCUS       DACAOP010000257         1274 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.265, whole genome shotgun sequence.
ACCESSION   DACAOP010000257 DACAOP010000000
VERSION     DACAOP010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1274
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.265"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            47..1267
                     /locus_tag="IT892_004645"
     CDS             47..1267
                     /locus_tag="IT892_004645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISKox3 family transposase"
                     /protein_id="HAP3137747.1"
                     /translation="MDEKSLYAHILNLSDPWQVKSLSLDENAGSVTVTIEIAENTRLA
                     CPTCGKSCSVHDHRHRKWRHLDTCQFTTIVEADVPRIMCPEHGCLTLPVPWAGPGSRY
                     TLLFESFVLSWLKISTVDAVRKQLKLSWNAVDGIMTRAVKRGLARIKKPLSARHMNVD
                     EVAFKKGHRYITVISDRDGRALALTDDRGTESLAGYLRTLTDGQLLAIKTLSMDMNAG
                     YIRAARIHLPSAVEKIAFDRFHVAKQLGEVVDKTRQNEHPHLPVESRHQAKGTRFLWQ
                     YSDKWMTESRQEKLMWLRAQMKLTSQCWALKELAKDIWNRPWSEERRSDWQRWLALAA
                     NSDVPMMKNAAKTIGKRLYGILNAMRHSVSNGNAEALNSKIRLLRIKARGYRNRERFK
                     LGVMFHYGKLNMAF"
BASE COUNT          325 a          312 c          357 g          280 t
ORIGIN      
        1 gctgaaggca tgataatggt gtatttaatc gccagaggtc accgccatgg acgaaaagtc
       61 cctctacgct catattctca acctgtccga tccgtggcag gtaaagtccc tttctctcga
      121 tgaaaatgcc ggttctgtta ctgtcactat tgagatcgct gaaaacaccc ggctagcctg
      181 tccgacctgc ggtaaatcct gttctgttca cgatcaccgt catcgtaaat ggcgccatct
      241 tgatacctgc cagttcacca ctattgttga agccgatgtt ccacgaatta tgtgtccgga
      301 gcatggctgc ctgacgttgc ctgttccgtg ggctggcccc ggaagccggt atacgttgct
      361 attcgaatcg ttcgttctct catggctgaa aatcagcacc gttgatgctg tcaggaagca
      421 acttaagctc agttggaatg cggttgacgg cattatgacc cgggcagtta agcgaggtct
      481 tgcccggata aaaaagccat tatccgcccg tcatatgaat gtggatgagg tcgcctttaa
      541 aaaaggacat cgttacataa cggtgatctc cgatcgcgat ggtcgggcgc tggccttaac
      601 ggatgatcgc ggcacagaga gtcttgccgg ctatcttcgc acgctcactg atgggcagtt
      661 gctggctatc aaaacgctct caatggacat gaacgcgggc tatataagag cagcgcgtat
      721 ccacttaccc agtgcggttg agaaaatcgc ctttgaccgc ttccatgtgg cgaagcaact
      781 gggcgaggta gttgataaaa cccgtcagaa tgaacatccg cacctccctg ttgaaagccg
      841 acaccaggca aaaggaaccc gcttcctgtg gcagtacagc gataagtgga tgaccgaatc
      901 ccggcaggaa aagctgatgt ggctgcgtgc acagatgaag ctgacgagcc agtgctgggc
      961 gctgaaagag ctggcaaagg atatctggaa caggccatgg agcgaggaaa gacggagtga
     1021 ctggcagaga tggttggcgc tggcggctaa cagtgacgtt cccatgatga aaaatgccgc
     1081 gaaaacgata ggaaaaaggc tgtacgggat cctgaatgcg atgcgacaca gtgtctcaaa
     1141 cggaaatgcg gaggcactta acagcaagat caggctgctg aggataaaag ccaggggata
     1201 ccgaaaccgg gagcgcttta aactgggggt gatgttccac tacggaaagc tgaatatggc
     1261 gttctgagcc ttcc
//
LOCUS       DACAOP010000258         1234 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.266, whole genome shotgun sequence.
ACCESSION   DACAOP010000258 DACAOP010000000
VERSION     DACAOP010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1234
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.266"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(55..762)
                     /locus_tag="IT892_004646"
     CDS             complement(55..762)
                     /locus_tag="IT892_004646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137748.1"
                     /translation="MRKKIEMSLINSPANGVVIKRIISDGLKEIVSLKEQILLETTAK
                     IQSIEEKREEKVIQGYYDGYAKGIIDVMDNFIPLISLLSSELEKNRINMINDLKSILL
                     KSSEEVEVFIKIFESWVTKLPSISGPLNLYIPTSFKDKSIEVESYFVDKSIWNVHISY
                     HDDKRFVFFTDQFIAEFSPQEFVDNCEQYLISNHCFSPDKVNEICEHARHYLVERMCE
                     IDSLAMNNSDLTTPEDL"
     gene            complement(704..>1234)
                     /locus_tag="IT892_004647"
     CDS             complement(704..>1234)
                     /locus_tag="IT892_004647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion apparatus protein OrgA/MxiK"
                     /protein_id="HAP3137749.1"
                     /translation="PQRVSLNNARISNPVLRSITNEMILLQYNLSVEHFSLNSSLIYY
                     INNWKLFPLICLLSGCHFYRERFAERGFFYKVPDVLRNYLSAIPVEINEKARYKPGIV
                     NYQNIITCGFSTLLPYVRQQPLAMQQRFNLLFPDFVDHIQLPLPLASTLLERITFYAK
                     KNRDELDKLSCKWCCD"
BASE COUNT          412 a          221 c          188 g          413 t
ORIGIN      
        1 gtttaaaata ttagaattag attatattca agtcattaag ccggagacag tgatctataa
       61 gtcctctggg gtcgtcaaat cagaattatt catagccaaa gaatctattt cacacattct
      121 ttcaactaaa taatgtctgg catgttcaca gatttcatta accttgtcag gggaaaaaca
      181 gtgattgcta attaaatatt gctcacaatt atccacaaat tcctgcggac taaactcagc
      241 aataaattga tctgtaaaaa aaacaaaacg tttgtcatca tgatatgaaa tatggacatt
      301 ccatattgac ttgtcgacaa aatatgactc tacttcaata gacttatctt tgaaactggt
      361 aggtatatag agatttaaag ggcctgatat tgacggtaat tttgttaccc aactttcaaa
      421 aattttgata aaaacttcaa cttcctctga agattttaac aatatgctct tcagatcgtt
      481 tatcatattt attctgtttt tttctaattc tgagctcagc aaacttatca agggtataaa
      541 attatccatc acatcaataa tgcctttcgc atagccatca taataacctt gaataacttt
      601 ttcttctctc ttttcctcaa tactctgaat ttttgcggtg gtttcaagaa ggatctgttc
      661 ttttagagaa actatttctt tcaatccatc agaaattatt cttttaatca caacaccatt
      721 tgcaggagag tttatcaagc tcatctctat tttttttcgc ataaaatgta attctctcca
      781 aaagagtaga cgcaagtggt aacggcaatt gtatgtggtc aacaaaatca ggaaataata
      841 aattaaatcg ttgctgcatt gccaacggtt gttgccttac atagggcaac aacgttgaaa
      901 aaccacatgt gatgatattc tgatagttaa cgataccagg tttatatcgt gccttttcat
      961 ttatttccac cggtatagct gataaataat tccttagcac atcaggaacc ttgtaaaaaa
     1021 atccgcgttc tgcaaacctt tctcgataaa agtgacaacc actgagtaaa cagatcaatg
     1081 gaaataattt ccaattgttt atgtagtaaa taagtgaact attcagactg aaatgctcaa
     1141 ctgaaagatt gtactgtagg agtatcattt cattggtaat agatctaagt accggattgc
     1201 taatacgtgc attattcaaa cttactcgtt gagg
//
LOCUS       DACAOP010000259         1232 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.267, whole genome shotgun sequence.
ACCESSION   DACAOP010000259 DACAOP010000000
VERSION     DACAOP010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.267"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            1..852
                     /locus_tag="IT892_004648"
                     /pseudo
     CDS             1..852
                     /locus_tag="IT892_004648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311184.2"
                     /note="ElaD; specific cysteine protease which targets
                     ubiquitin and ubiquitin-like proteins covalently bound to
                     target proteins; SseL in Salmonella is required for
                     macrophage killing and virulence, and it is secreted by
                     the salmonella pathogenicity island 2 type III secretion
                     system; frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="deubiquitinase"
BASE COUNT          454 a          232 c          195 g          351 t
ORIGIN      
        1 cttcgaaatt aatgacaatt atcggtgagg acattcctct tatatcagaa aaacagtcgc
       61 tttcaaaggt acttttaaat gataagaata atgaactgag cgatgggaca aacttctggg
      121 ataaaaatcg tcaattaacc acagatgaaa tagcttgcta tcttaaaaag atagccgcaa
      181 atgcaaaaaa tactcaagtc aattatccta ctgatttcta cctccccaat tccaacagca
      241 cttacctgga agtcgctctc aatgataata ttaggagcga tccattatgg ccgaaagcag
      301 tccagttatt ccccataaat actggcggac actggatatt agtttcgcta caaaaaatag
      361 ttaatgaaaa aaaataacac acaacaaata aaatgcatca tattcaattc attacgtgca
      421 ctaggccatg aaaaagaaaa ttcacttaag cgtatcatta atagttttaa ttctgaactc
      481 atgggagaaa tgtcgaataa taatataaca gatcatttaa ctgaacccga gataatattt
      541 ttacatgccg atcttcagca atacttaagc caaagttgcg gtgcatttgt gtgcatggca
      601 gcccaggaag tgattgaaca aagggaaagc aattccgaca gcgccctcta tacgttatta
      661 aaaaactatg ctgacagatt taaaaaatat tcagcagaag agcagtacga aattgatttt
      721 caacatcgac aggtaaacag aaattgttat ttagataaat atggcgatgc aaatatcaat
      781 gattattata gagacttaga aataaaacac tcacaacccc aaaatagagc atcaggcaaa
      841 agagtaagtt aacatcattg ttaattaatt cgaccagtca gcaaatatgc tgactggtcg
      901 aacatagttt gctaaaaagt catcactgac tgatgtcagt cacaccaccc gccagttcaa
      961 tctgcgggta tttccagcgt atcgcggcac gcgattgctg gtctgttgat gtagtggatt
     1021 gtagttgctg atttttctta ccctaagatt tcaattcaat ctgccaataa ataacataat
     1081 tatatttttt cctcatatga attccttttt aatatagcga actcactgta aaaaaaacac
     1141 tttttgtata tctctaccaa ccgtaataaa ataaacactc acagctcatt ataaataata
     1201 atgaaataac gccttttatt gataatttac at
//
LOCUS       DACAOP010000260         1222 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.269, whole genome shotgun sequence.
ACCESSION   DACAOP010000260 DACAOP010000000
VERSION     DACAOP010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1222
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.269"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..634
                     /locus_tag="IT892_004649"
     CDS             <1..634
                     /locus_tag="IT892_004649"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137750.1"
                     /translation="KLIREIFSRLNQGAVKLSDQEIRHALYPGGFDELLEELGNIDAI
                     KNFGLAETTTVKRDSREPDEQVLRFFAFYEDNFFDYFDSSLKEFLDDHMEKFSDLKDD
                     ELNIMRERFKTSLSKCEKIFGEDVFTNPTVRRKRKGLVHYDILMPTIGKLNDDIVNEK
                     SEQIRNAWFTLCSSAEFKKTLSGGLQNKSSVMKRRASWVALLKEVIDGKY"
     gene            621..1199
                     /locus_tag="IT892_004650"
     CDS             621..1199
                     /locus_tag="IT892_004650"
                     /inference="COORDINATES: protein motif:HMM:NF037889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137751.1"
                     /translation="MENTEYYDGYRSLFLSLKEIIKETEQQAILEENEFFNKNINFFV
                     KSYLITLCTYLESYLTEVATWHCDTINRRLKAACLPHNFLLWRVKKDVKDKELKYIDA
                     DLKVEKSEVSDSLSGNPYKTIKAFSYLGVNLLNSAEFNANKDVVNAVVVKRNNIIHHN
                     DNANDISLTDVSGYVDLFVSYMAAIDNMVCGK"
BASE COUNT          408 a          151 c          267 g          396 t
ORIGIN      
        1 aaaattaata agagagatat tttctagact caatcagggg gcagttaaac tttctgatca
       61 agaaataaga catgcgttat atccgggagg gtttgatgaa ttattagaag agttaggtaa
      121 tattgatgcc attaaaaatt ttggtttggc ggaaacaact acagtaaaaa gagatagtcg
      181 tgagccagac gaacaagttt tgcgtttttt tgcattttat gaagataact tttttgatta
      241 ctttgatagc tccttgaaag aattcttgga tgatcatatg gaaaaatttt cagacttaaa
      301 agatgatgaa ctgaatatta tgagggagag attcaaaaca tcattatcta agtgtgaaaa
      361 aatatttggt gaagatgtat ttacaaaccc tacagttagg agaaaacgta aagggttagt
      421 tcattatgac attttaatgc ctacaattgg caagttaaat gatgatattg taaatgaaaa
      481 gtccgaacaa atacggaatg cttggtttac tctttgttca agtgctgagt tcaaaaaaac
      541 tttatcaggt gggctacaga ataagagttc ggtgatgaag cgtagggcta gttgggtggc
      601 acttcttaag gaagttattg atggaaaata ctgaatacta tgatggatat cgttcattat
      661 ttttatcctt aaaagaaatt attaaggaga cggagcaaca ggctatcctt gaggaaaatg
      721 aattcttcaa taagaacatt aatttttttg ttaaatcgta tcttattaca ctctgcactt
      781 atttagagtc gtatttgact gaggttgcaa catggcactg cgataccatc aatcgcaggc
      841 tcaaagcagc ctgcttgcca cacaattttt tgctttggcg agtcaaaaaa gatgttaaag
      901 ataaggagtt gaaatatata gatgctgatt taaaggttga gaaaagtgag gtgtcggata
      961 gcctgtctgg taatccttac aagacgatta aggcattttc ttatttgggt gttaatcttt
     1021 tgaattcggc ggaatttaat gcgaataagg atgttgtgaa tgcagtggtt gtaaagagaa
     1081 ataacattat tcatcataac gacaatgcaa atgatattag tctcactgac gtaagtggtt
     1141 atgtagatct gtttgtatcc tatatggctg cgatagataa tatggtttgt ggaaaataat
     1201 gttttaatat tcgtggggct gt
//
LOCUS       DACAOP010000261         1215 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.270, whole genome shotgun sequence.
ACCESSION   DACAOP010000261 DACAOP010000000
VERSION     DACAOP010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.270"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..152)
                     /locus_tag="IT892_004651"
     CDS             complement(<1..152)
                     /locus_tag="IT892_004651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137752.1"
                     /translation="MIYITIFMILPCPVPCSHVFLYVFYIFLFLVLFIMTIYQSSQKL
                     HFSNCY"
     gene            234..1215
                     /locus_tag="IT892_004652"
                     /pseudo
     CDS             234..1215
                     /locus_tag="IT892_004652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027427.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT          439 a          170 c          283 g          323 t
ORIGIN      
        1 tgataacaat ttgaaaaatg aagtttttga ctggattggt aaatggtcat aatgaacaac
       61 accagaaaga gaaaaatata aaatacatac agaaagacat gagagcaagg gacggggcag
      121 ggcaagatca tgaaaattgt gatgtaaatc acgattttca tctttgcttt aacgcctaca
      181 ggtgatcaaa atttaacctt tggaataact aaaaagataa aaaaggacgc caggtgagta
      241 ttcaaagttt gcttgattat atttcagtga cccctgatat acgacaacaa ggaaaggtta
      301 aacataaatt atctgctatt ttgtttctca ccgtatgtgc agtaattgca ggtgccgatg
      361 agtggcagga aattgaagat tttggacatg aaagacttga atggctaaag aaatatggtg
      421 attttgataa tggcattccg gtcgatgaca ccattgcacg cgttgtgagt aacattgaca
      481 gtttggcctt tgaaaagatg tttattgaat ggatgcagga gtgccatgaa atcactgatg
      541 gtgaaattat agcaatagat ggaaagacca taagaggctc ctttgataag ggaaaaagaa
      601 aaggagcaat ccatatggtg agtgcattct cgaacgaaaa tggtgttgta ctggggcagg
      661 tgaaaacgga agccaaaagt aatgagatta cagccattcc agagttgctt aacctactgt
      721 atttaaagaa aaatttgata accattgatg ctatgggctg tcagaaagat atctcttcga
      781 agatcaaaga taaaaaagca gattatcttc tggcagtaaa aggcaatcag gggaaattac
      841 atcatgcatt cgaggaaaaa tttcctgtaa atgtgttttc taattataaa ggcgattcgt
      901 ttagtacgca ggagataagt catggaagaa aagaaacacg tttgcatatt gtcagtaacg
      961 taacgcctga acttttgtga ttttgaattc gaatggaagg gattaaaaaa gctttgtgta
     1021 gcattgtcat tcaggcagaa gaaagaagat aaatcagcag aaggtgtaag catccgatat
     1081 tatatttcat caaaggatat ggatgctaaa gaatttgcac atgctatcag agcgcactgg
     1141 ctgatcgagc acagtcttca ttgggtgtta gatgtaaaaa tgaatgaaga tgccagccgg
     1201 ataagaagag gaaac
//
LOCUS       DACAOP010000262         1186 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.271, whole genome shotgun sequence.
ACCESSION   DACAOP010000262 DACAOP010000000
VERSION     DACAOP010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1186
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.271"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..921
                     /gene="tssI"
                     /locus_tag="IT892_004653"
     CDS             <1..921
                     /gene="tssI"
                     /locus_tag="IT892_004653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HAP3137753.1"
                     /translation="YNPSNQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDP
                     DQPIIMGRTYHHENRTPGSLPGTKTQMTIRSKTYKGSGFNELKFDDATGKEQVYIHAQ
                     KNMNTEVLNNRTTDVINNHAETIGNNQMIAVTNNQIQTVGVNQIETVGSNQIIKVGSV
                     QVETIGLVRALTVGVAYQTTVGGIMNTSVALMQSSQIGLHKSLRVGLGYDVKVGNNVT
                     FTVGKTKKDDTGQTAIYSAGEHLELCCGKARLVLTKDGQIFLNGTKIHLQGKEQVNGD
                     SLLINWNCAASKSPPKTPDEKQDTPDMREY"
     gene            988..>1186
                     /locus_tag="IT892_004654"
     CDS             988..>1186
                     /locus_tag="IT892_004654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005136314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137754.1"
                     /translation="MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMT
                     SGNPVNPLLGAKVLPGETDLAL"
BASE COUNT          316 a          277 c          356 g          237 t
ORIGIN      
        1 tataacccgt caaaccagga cagttcatgc tggatccgtg tggcacaggc gtgggcaggc
       61 accggctttg gcaacctggc gataccgcga gtgggtcagg aggtgattgt ggacttcctc
      121 aacggcgacc cggaccagcc gattattatg gggcgtacct accaccatga aaaccgcaca
      181 cccggcagcc tgccggggac gaagacgcag atgaccattc gttcgaaaac ctataagggc
      241 agcgggttta atgaactgaa gtttgacgat gcgacaggga aagaacaggt ctacatccac
      301 gcgcagaaga acatgaacac cgaggtgctg aataaccgca ccactgatgt gataaacaac
      361 catgctgaaa ccattggcaa caatcagatg attgcggtta ccaacaatca gatacagacg
      421 gtgggtgtca accagataga gacggtgggc agtaaccaga taattaaagt gggttctgtt
      481 caggtggaaa cgattggact tgttcgtgcg ctgaccgtgg gcgtggcgta ccagacgacg
      541 gtaggtggca ttatgaacac ttcggtggct ctgatgcagt cctcgcagat cggtttgcat
      601 aaatcgttga gggtcgggct gggttatgac gtcaaagtcg gaaataacgt taccttcacc
      661 gttggtaaaa cgaaaaagga tgataccggg cagaccgcga tttactccgc cggtgagcat
      721 ctggagctct gctgtggtaa ggcaaggctg gtgctgacga aggacggaca aatttttctc
      781 aacggcacaa aaattcattt gcagggtaag gagcaggtta atggtgactc actgttgatt
      841 aactggaact gtgcagcctc gaaatcccca ccgaagaccc ctgatgaaaa gcaggatacg
      901 ccggatatga gagagtactg atcccgtacc tgttcggtat tcagtaacaa accagcatta
      961 aaaataaaca gaagaaggaa ttgaatcatg agcggaaaac cagcggcgcg tcagggagat
     1021 atgactcagt atggcggtcc cattgtccag ggttcggcag gtgtaagaat tggcgcgccc
     1081 accggcgtgg cgtgctcggt gtgtccgggc gggatgactt cgggcaaccc ggtaaatccg
     1141 ctgctggggg cgaaggtgct gcccggcgag acggaccttg cgctgc
//
LOCUS       DACAOP010000263         1185 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.272, whole genome shotgun sequence.
ACCESSION   DACAOP010000263 DACAOP010000000
VERSION     DACAOP010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1185
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.272"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            593..>1185
                     /locus_tag="IT892_004655"
     CDS             593..>1185
                     /locus_tag="IT892_004655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137755.1"
                     /translation="MKLLNKKYYNLEPNFDYLKDSFILGLAWKKTDRFVRTHNWYADL
                     LALDKCAFDISDEVTSWSSEAVNRNLSKSDIELIPAPKRASWFFNKGKWTTNKDDRKL
                     RPLANISIKDQSFATAVTMCLADAIETRQKDCSLRNLGYAEHVNKKVVSYGNRLVCDW
                     DNERARFRWGGSEYYRKFSTDYRNFLQRPVYIGRETV"
BASE COUNT          385 a          201 c          268 g          331 t
ORIGIN      
        1 cggtgaaaaa agacaaaacc ccgcgcaccg gaaaggtggc gggggattca caacgataat
       61 atctgtctga aattatttgg aatgcaggta tatgtggctg atttgtatca gctaatgagt
      121 acaggtctga atctaatctg acagtccgct ctgtgccagg agcggacgtt gataaccaaa
      181 tttaagtatc acccaaggct tatatgagaa tggtcttgat gcagcgttca gtaaaactcg
      241 aacgcttcac cgaaatgtct tagagtggga gaatattcta cttatgccca tatcgattgg
      301 ttgggggatt gtcttatcac tcaaagaacc ggaaaaccga taccggaaaa actctaactc
      361 agtgggcaat ttttgttgac cattacaacg ctctctcttg tacaacctgg tttatggcat
      421 gacagacacg actgatttat caggtgagcc cattagacat gacaaacttt tgacacttcc
      481 cgtggattat tcgattcagg aacggtagta tagttatatt aggtgataca aacagtgaat
      541 ttcaatactg tagttgaaat gagtaaaacg cttagcatta agttgagaaa aaatgaaact
      601 acttaataaa aagtattaca acctcgaacc aaactttgac taccttaagg actcatttat
      661 tttagggctg gcttggaaaa aaacggatcg ttttgtaaga actcataatt ggtatgcaga
      721 tcttttagcg ctagacaagt gtgcgtttga tattagtgat gaggtcacta gttggtcaag
      781 tgaggccgta aataggaatc tgtctaaaag tgatattgaa ttaataccag ctccaaaaag
      841 agcaagctgg ttctttaata aagggaagtg gactactaat aaagatgata gaaaactaag
      901 acctttagct aatatatcta ttaaggatca gtcttttgca acagcagtaa ccatgtgtct
      961 tgctgatgcg atagaaacga gacagaaaga ctgctcattg cgtaatcttg gctatgctga
     1021 gcatgtaaat aaaaaggttg ttagttacgg aaataggctt gtctgtgatt gggacaatga
     1081 aagggcgaga tttcgttggg gcggcagcga gtattatagg aaattctcca ccgattatcg
     1141 aaactttcta caaagacctg tctatatagg tagggaaact gtaaa
//
LOCUS       DACAOP010000264         1154 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.273, whole genome shotgun sequence.
ACCESSION   DACAOP010000264 DACAOP010000000
VERSION     DACAOP010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1154
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.273"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>1154
                     /gene="ag43"
                     /locus_tag="IT892_004656"
     CDS             <1..>1154
                     /gene="ag43"
                     /locus_tag="IT892_004656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HAP3137756.1"
                     /translation="TNVGNSNLGVATSGQGIRVVDAQNGATTEEGAFALSRPLQAGAF
                     NYTLNRDSDEDWYLRSENAYRAEVPLYTSMLTQAMDYDRILAGSRSHQTGVNGENNSV
                     RLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVHGAAGH
                     SSVDVKDDDGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDF
                     RARGWGWLGSLETGLPFSITDNLMLEPQLHYTWQGLSLDDGQDNAGYVKFGHGSAQHV
                     RAGFRLGSHNDMSFGEGTSSRDTLRDSAKHRVRELPVNWWVQPSVIRTFSSRGDMSMG
                     TAAAGSNMTFSPSRNGTSLDLQAGLEARVRENITLGVQAGYAHSVSGSSA"
BASE COUNT          246 a          331 c          352 g          225 t
ORIGIN      
        1 acaaatgtcg gaaacagtaa cctcggggtg gcaacctccg gacagggtat ccgggttgtg
       61 gatgcacaga atggcgccac cacagaagaa ggtgcgtttg ccctgagtcg cccgcttcag
      121 gccggcgcct ttaactacac cctgaaccgt gacagcgatg aagactggta cctgcgcagt
      181 gaaaatgctt atcgtgctga agtccccctg tatacatcca tgctgacaca ggcaatggac
      241 tatgaccgga ttctggcagg ctcccgcagc catcagaccg gtgtaaacgg tgaaaataac
      301 agcgtccgtc tcagcattca gggcggtcat ctcggtcacg ataacaacgg cggtattgcc
      361 cgtggagcca cgccggaaag cagcggcagc tatggcttcg tccgtctgga gggtgacctg
      421 ctcagaacag aggttgccgg tatgtctctg acgacagggg tgcatggtgc cgcaggccat
      481 tcttccgttg atgttaagga tgatgacggt tcccgcgccg gcacggtccg ggatgatgcc
      541 ggcagcctgg gcggatacct gaatctggta cacacgtcct ccggcctgtg ggctgacatt
      601 gtggcacagg gaacccgcca cagcatgaaa gcgtcatcgg ataataacga cttccgcgcc
      661 cggggctggg gctggctggg ctcactggaa accggtctgc ccttcagtat cactgacaac
      721 ctgatgctgg agccacaact gcactatacc tggcagggac tttccctgga tgacggccag
      781 gataacgccg gttatgtgaa gttcgggcat ggcagtgcac aacatgtgcg tgccggtttc
      841 cgtctgggca gccacaacga tatgagcttt ggtgaaggca cctcatcccg tgacaccctg
      901 cgcgacagtg caaaacaccg tgtgcgtgaa ctgccggtga actggtgggt acagccttct
      961 gttatccgca ccttcagttc ccggggtgac atgagcatgg ggacagccgc cgccggcagt
     1021 aacatgacgt tctcaccgtc ccggaatggc acgtcactgg acctgcaggc cggactggaa
     1081 gcccgtgtcc gggaaaatat caccctgggc gttcaggccg gttatgccca cagtgtcagc
     1141 ggcagcagcg ctga
//
LOCUS       DACAOP010000265         1114 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.274, whole genome shotgun sequence.
ACCESSION   DACAOP010000265 DACAOP010000000
VERSION     DACAOP010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1114
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.274"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..136
                     /locus_tag="IT892_004657"
     CDS             <1..136
                     /locus_tag="IT892_004657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP3137757.1"
                     /translation="AHAITDYIVGYYSALRPHEYNGGLPPNESENRYWKNSNAVASFS
                     "
     gene            complement(146..1066)
                     /locus_tag="IT892_004658"
                     /pseudo
     CDS             complement(146..1066)
                     /locus_tag="IT892_004658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238717.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          321 a          261 c          218 g          314 t
ORIGIN      
        1 agctcacgca ataacggact atatcgttgg atattacagc gcactaagac cgcacgaata
       61 taatggtggg ttaccaccaa acgaatcaga aaaccgatac tggaaaaact ctaacgcggt
      121 ggccagtttt agttgaccac aacataccga tttcaatgta gttcagacga tcagaatctt
      181 tgtaacctgc tacgtccagt gctttagaat aggagtaacc gatggatgga cgcagaccga
      241 agtcgaactg atattgcaga acagcttcga agttttgtgt tttgttcaca acatcaccgt
      301 cgtcggaatt catgttgtga gattcaccgt acatcacagc agcatagacg ttgttgggat
      361 catattttgt tgacagtgcc caaacttctg ctttttcacc tttactatca ctagactgga
      421 aatcagtacg gtcagagttt gcgtaagcac cagtaaatga gaaaccgtca atagtgtaag
      481 ttacagataa accatggcca tcgccatttg ctttgtagtt gcctgtacct tcatttttac
      541 cctgatattg cagagcaaaa tttagacctt caaccatgcc aaagaaatct gtgttacgat
      601 aggttgcaac accgttggta cggttggtca tgaacaggtc agtaccagcc catgaatcac
      661 cgccccactc aacaaacata tcagtaaatg cttctgcatc atacgcgaca ccgacattac
      721 gaccatagtc gaatgaacca aaatctttgt aactcaaacc agcataagcc aaacgagttt
      781 ggtcagggtt gtgtctgttt gatgcttcca ggtctagttc aaactgaccg taaccagtca
      841 attcagggtt gatctgagtt tcacctttca cgcctacacg ggcataagag gtatcttgag
      901 aattatcgcc tttttcacca ttttcacggt cggtcagaat gcgctcacca accatcttgc
      961 cgtacagatc cagtttattg ccatctttat tataaatttc agccgcattt gctgcgccag
     1021 caactaataa cgccgggacc agcattgcca gaacttttct tttcattatg tattcccttg
     1081 tgattataat cttcatgaat atatcaataa gtgc
//
LOCUS       DACAOP010000266         1092 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.275, whole genome shotgun sequence.
ACCESSION   DACAOP010000266 DACAOP010000000
VERSION     DACAOP010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1092
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.275"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(150..269)
                     /locus_tag="IT892_004659"
     CDS             complement(150..269)
                     /locus_tag="IT892_004659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP3137758.1"
                     /translation="MPLSYAGYHHFIMMSLVSGEHNTPALSLQDESPGLVPAG"
     gene            complement(230..415)
                     /locus_tag="IT892_004660"
     CDS             complement(230..415)
                     /locus_tag="IT892_004660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137759.1"
                     /translation="MSRRYSSATITLVILFCRRPHCRKISVRQYYQKRVIFYPTTLQR
                     TACKKCLFLMRDIIISS"
     gene            516..689
                     /locus_tag="IT892_004661"
     CDS             516..689
                     /locus_tag="IT892_004661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137760.1"
                     /translation="MSYSSFKIILIHVKNIIPIITATLILNYLNNSERSLVKQILIED
                     EIIVCATYLIPDI"
     gene            751..1035
                     /locus_tag="IT892_004662"
     CDS             751..1035
                     /locus_tag="IT892_004662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper family protein"
                     /protein_id="HAP3137761.1"
                     /translation="MADMNRTTKGALLGAGVGLLTGNGVNGVLKGAAVGAGVGAVTEK
                     GRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVIGGTGGAILGKMK"
BASE COUNT          315 a          222 c          250 g          305 t
ORIGIN      
        1 ggttcatttc cataccgttc cccaggcgca tgttgtaact cagcgttgca cccagttcac
       61 gatatatact gcgggtatcg actgatttcg attccatgcc attggataaa tgatagtagc
      121 gtctaagtga cctaagctct gctgcaacat cagcccgcag gcaccagacc aggggattca
      181 tcctgaagag acagcgcagg tgtattgtgt tcaccgctca ccaaagacat catgatgaaa
      241 tgatgatatc ccgcataaga aagaggcatt ttttacacgc agtgcgctga agtgtagttg
      301 gataaaaaat cactcttttc tgataatact gtcgtacgct tatctttcga caatgaggcc
      361 gtcggcaaaa taaaatgact aatgtaatcg ttgctgatga atatcttctg ctcacataaa
      421 aatcacacaa taatattgat aaatcagatt atcttacctt tacaacattg cgttaacagt
      481 caatgacact tcttgaataa aaatattgtc aatcaatgag ttattcctca tttaagatta
      541 ttctcattca cgtaaaaaac ataattccta tcatcacagc cacgctcatt ttgaattatc
      601 tgaataatag cgagcgttct ttagttaagc agatcttaat tgaagacgaa attattgtgt
      661 gtgcaactta cttaataccg gacatctaag ttgaagaaaa aaatacttgc cttcgggctt
      721 atctcagcat tgttctgctc cacgccagcg atggcggata tgaaccgcac cacgaaaggt
      781 gcattgctag gcgcaggcgt tggtttactt actggcaatg gtgttaatgg cgtactgaaa
      841 ggtgcagctg ttggcgctgg tgttggtgca gtaacagaaa aaggccgcga cggtaaaaat
      901 gcgcgtaaag gtgcaaaagt gggtgccgcc gttggtgctg tcactggcgt tctgaccggc
      961 aatggcctcg aaggggcgat taaaggtgcc gtgattggcg gtacgggtgg tgcaattctg
     1021 ggtaaaatga aataaggaat gatgatgaaa aaatttgctt tactggcggg cctgtttgtt
     1081 ttcgcaccaa tg
//
LOCUS       DACAOP010000267         1049 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.277, whole genome shotgun sequence.
ACCESSION   DACAOP010000267 DACAOP010000000
VERSION     DACAOP010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.277"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..924
                     /locus_tag="IT892_004663"
     CDS             <1..924
                     /locus_tag="IT892_004663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS5 family transposase"
                     /protein_id="HAP3137762.1"
                     /translation="RKEIFLSRMEQILPWQNMVEVIEPFYPKAGNGRRPYPLETMLRI
                     HCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQL
                     FKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPEMHQTKKGNQWHFGMKA
                     HIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDV
                     DWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRAKVEHPFRIIKRQFGFVKARYKG
                     LLKNDNQLAMLFTLANLFRADQMIRQWERSH"
BASE COUNT          295 a          279 c          279 g          196 t
ORIGIN      
        1 agaaaagaga ttttcttgtc ccgcatggag cagattctgc catggcaaaa catggtggaa
       61 gtcatcgagc cgttttaccc caaggctggt aatggccggc gaccttatcc gctggaaacc
      121 atgctacgca ttcactgcat gcagcattgg tacaacctga gcgatggcgc gatggaagat
      181 gctctgtacg aaatcgcctc catgcgtctg tttgcccggt tatccctgga tagcgccttg
      241 cctgaccgca ccaccatcat gaatttccgc cacctgctgg agcagcatca actggcccgc
      301 caattgttca agaccatcaa tcgctggctg gccgaagcag gcgtcatgat gactcaaggc
      361 accttggtcg atgccaccat cattgaggca cccagctcga ccaagaacaa agagcagcaa
      421 cgcgatccgg agatgcatca gaccaagaaa ggcaatcaat ggcactttgg catgaaggcc
      481 cacattggtg tcgatgccaa gagtggcctg acccacagcc tagtcaccac cgcggccaac
      541 gagcatgacc tcaatcagct gggtaatctg ctgcatggag aggagcaatt tgtctcagcc
      601 gatgccggct accaaggggc gccacagcgc gaggagctgg ccgaggtgga tgtggactgg
      661 ctgatcgccg agcgccccgg caaggtaaga accttgaaac agcatccacg caagaacaaa
      721 acggccatca acatcgaata catgaaagcc agcatccggg ccaaggtgga gcacccattt
      781 cgcatcatca agcgacagtt cggcttcgtg aaagccagat acaaggggtt gctgaaaaac
      841 gataaccaac tggcgatgtt attcacgctg gccaacctgt ttcgggcgga ccaaatgata
      901 cgtcagtggg agagatctca ctaaaaactg gggataacgc cttaaatggc gaagaaacgg
      961 tctaaatagg ctgattcaag gcatttacgg gagaaaaaat cggctcaaac atgaagaaat
     1021 gaaatgactg agtcagccga gaagaattt
//
LOCUS       DACAOP010000268         1040 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.278, whole genome shotgun sequence.
ACCESSION   DACAOP010000268 DACAOP010000000
VERSION     DACAOP010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1040
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.278"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..893
                     /locus_tag="IT892_004664"
     CDS             <1..893
                     /locus_tag="IT892_004664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS4-like element IS421 family transposase"
                     /protein_id="HAP3137763.1"
                     /translation="VALLKRLRNAADWFGILAAQTLAVRAAVTGCTSGKRLRLVDGTA
                     ISAPGGGSAEWRLHMGYDPHTCQFTDFELTDSRDAERLDRFAQTADEIRIADRGFGSR
                     PECIRSLAFGEADYIVRVHWRGLRWLTAEGMRFDMMGFLRGLDCGKNGETTVMIGNSG
                     NKKAGAPFPARLIAVSLPPEKALISKTRLLSENRRKGRVVQAETLEAAGHVLLLTSLP
                     EDEYSAEQVADCYRLRWQIELAFKRLKSLLHLDALRAKEPELAKAWIFANLLAAFLID
                     DIIQPSLDFPPRSAGSEKKN"
BASE COUNT          268 a          248 c          285 g          239 t
ORIGIN      
        1 acgtggctct cctgaagcgg ctgcggaatg ccgccgactg gtttggcata cttgccgcac
       61 aaacacttgc tgtacgcgcc gcagttacgg gttgtacaag cggaaagaga ttgcgtcttg
      121 tcgatggaac agcaatcagt gcgcccgggg gcggcagcgc tgaatggcga ctacatatgg
      181 gatatgatcc tcatacctgt cagttcactg attttgagct aaccgacagc agagacgctg
      241 aacggctgga ccgatttgcg caaacggcag acgagatacg cattgctgac cggggattcg
      301 gttcgcgtcc cgaatgtatc cgctcacttg cttttggaga agctgattat atcgtccggg
      361 ttcactggcg aggattgcgc tggttaactg cagaaggaat gcgctttgac atgatgggtt
      421 ttctgcgcgg gctggattgc ggtaagaacg gtgaaaccac tgtaatgata ggcaattcag
      481 gtaataaaaa agccggagct ccctttccgg cacgtctcat tgccgtatca cttcctcccg
      541 aaaaagcatt aatcagtaaa acccgactgc tcagcgagaa tcgtcgaaaa ggacgagtag
      601 ttcaggcgga aacgctggaa gcagcgggcc atgtgctatt gctaacatca ttaccggaag
      661 atgaatattc agcagagcaa gtggctgatt gttaccgtct gcgatggcaa attgaactgg
      721 cttttaagcg gctcaaaagt ttgctgcacc tggatgcttt gcgtgcaaag gaacctgaac
      781 tcgcgaaagc gtggatattt gctaatctac tcgccgcatt tttaattgac gacataatcc
      841 agccatcgct ggatttcccc cccagaagtg ccggatccga aaagaagaac taactcgttg
      901 tggagaataa caaaaatggt catctggagc ttacaggtgg ccattcgtgg gacagtatcc
      961 ctgacagcct acaaaacgca attgaagaac gcgaggcatc gtcttaacga ggcaccgagg
     1021 cgtcgcattc ttcagatggt
//
LOCUS       DACAOP010000269         1029 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.279, whole genome shotgun sequence.
ACCESSION   DACAOP010000269 DACAOP010000000
VERSION     DACAOP010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1029
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.279"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..273)
                     /locus_tag="IT892_004665"
     CDS             complement(<1..273)
                     /locus_tag="IT892_004665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP3137764.1"
                     /translation="MENKNHQQENFKSTYQSLVNSARILFVEKGYQAVSIDEISGKAL
                     VTKGAFYHHFKNKKQLLSACYKQQLIMIDAYITTKTDLTNGWSALES"
     gene            361..771
                     /locus_tag="IT892_004666"
                     /pseudo
     CDS             361..771
                     /locus_tag="IT892_004666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014656611.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(787..>1029)
                     /locus_tag="IT892_004667"
     CDS             complement(787..>1029)
                     /locus_tag="IT892_004667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAP3137765.1"
                     /translation="LIALMLQLTCWLAGVHAQKQGWDKHFQANTVRNRNVLSTVRLGM
                     EVLRHSGYTITREDLLVAATLLAQNLFTHGYALGKL"
BASE COUNT          307 a          179 c          204 g          339 t
ORIGIN      
        1 actttctaag gcagaccaac catttgttaa atcagttttt gttgtgatgt aggcatcaat
       61 cataattaat tgctgcttat aacaggcact gagtaattgt tttttatttt taaagtgatg
      121 ataaaaggca cctttggtca ccaacgcttt tcccgagatc tcatctattg aaacagcttg
      181 atagcctttt tcaacaaaca atattcgtgc tgagttaacc agtgattgat aggtactctt
      241 aaaattttct tgttgatgat ttttattttc catgatagat ttaaaataac ataccgtcag
      301 tatgtttatg gtatcatgat gatgtggtcg tgacaatctt aagaacattt aggttatttt
      361 atgtatattg aacagcattc tcgctatcaa aataaagcta ataacatcca attaagatat
      421 gatgataagc agtttcatac aacggttatc aaagatgttc tattatggat tgaacataat
      481 ttagatcagt ctttactgct tgatgatgtg gcgaataaag cgggttatac caagtggtat
      541 tttcagcggc tgttcaaaaa agtaacaggg gtcacactgg ctagctatat tcgtgctcgt
      601 cgtttgacga aagcggctgt tgagttgagg ttgacgaaaa aaactatcct tgagatcgca
      661 ttaaaatatc aatttgattc ccaacaatct tttacacgtc gatttaagta catttttaag
      721 gttacaccaa gttattatcg gcgtaataaa ttatgggaat tggaggcaat gcactgagag
      781 atcccctcat aatttcccca aagcgtaacc atgtgtgaat aaattttgag ctagtagggt
      841 tgcagccacg agtaagtctt cccttgttat tgtgtagcca gaatgccgca aaacttccat
      901 gcctaagcga actgttgaga gtacgtttcg atttctgact gtgttagcct ggaagtgctt
      961 gtcccaacct tgtttctgag catgaacgcc cgcaagccaa catgttagtt gaagcatcag
     1021 ggcgattag
//
LOCUS       DACAOP010000270          930 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.281, whole genome shotgun sequence.
ACCESSION   DACAOP010000270 DACAOP010000000
VERSION     DACAOP010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.281"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>930
                     /gene="ag43"
                     /locus_tag="IT892_004668"
     CDS             <1..>930
                     /gene="ag43"
                     /locus_tag="IT892_004668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HAP3137766.1"
                     /translation="TNVGNSNLGVATTGQGIRVVDAQNGATTEEGAFALSRPLQAGAF
                     NYTLNRDSDEDWYLRSENAYRAEVPLYASMLTQAMDYDRILAGSRSHQTGVNGENNSV
                     RLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVYGAAGH
                     SSVDVKDDDGYRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDF
                     RARGWGWLGSLETGLPFSITDNLMLEPQLQYTWQGLSLDDGQDNAGYVKFGHGSAQHV
                     RAGFRLGSHNDMTFGEGTSSRDTLRDSAKHSVRE"
BASE COUNT          203 a          262 c          283 g          182 t
ORIGIN      
        1 acaaatgtcg gaaacagtaa cctcggggtg gcaaccaccg gacagggtat ccgggttgtg
       61 gatgcacaga atggtgccac cacagaagaa ggtgcgtttg ccctgagccg cccgcttcag
      121 gccggcgcct ttaactacac cctgaaccgt gacagcgatg aagactggta cctgcgcagt
      181 gaaaatgctt atcgtgctga agtccccctg tatgcctcca tgctgacaca ggcaatggac
      241 tatgaccgga ttctggctgg ctcccgcagc catcagaccg gtgtaaacgg tgaaaataac
      301 agcgtccgtc tcagcattca gggcggtcat ctcgggcacg ataacaacgg cggtattgcc
      361 cgtggggcca cgccggaaag cagcggcagc tatggcttcg tccgtctgga gggtgacctg
      421 ctcagaacag aggttgccgg tatgtctctg acgacagggg tgtatggtgc tgcaggccat
      481 tcttccgttg atgttaagga tgatgacggc taccgcgccg gcacggtccg ggatgatgcc
      541 ggcagtctgg gcggatacct gaatctggta cacacatcct ccggcctgtg ggctgacatt
      601 gtggcacagg gaacccgcca cagcatgaaa gcgtcatcgg acaataacga cttccgcgcc
      661 cggggctggg gctggctggg ctcactggaa accggtctgc ccttcagtat cactgacaat
      721 ctgatgctgg agccacaact gcagtacacc tggcagggac tctccctgga tgacggccag
      781 gataacgccg gttatgtgaa gttcgggcat ggcagtgcac aacatgtgcg tgccggtttc
      841 cgtctgggca gccacaacga tatgaccttt ggtgaaggca cctcatcccg tgacaccctg
      901 cgcgacagtg ccaaacacag tgtgcgtgaa
//
LOCUS       DACAOP010000271          923 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.282, whole genome shotgun sequence.
ACCESSION   DACAOP010000271 DACAOP010000000
VERSION     DACAOP010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..923
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.282"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..645
                     /locus_tag="IT892_004669"
     CDS             <1..645
                     /locus_tag="IT892_004669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HAP3137767.1"
                     /translation="FRLSGHGHSMVITDLPGVGESRDRDAEYEALYRDILPELDLVLW
                     LIKADDRALSVDEYFWRHILHRGHQQVLFVVTQADKTEPCHEWDMAGIQPSPAQAQNI
                     REKTEAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALPDHAASPLMTRLQDELRTE
                     SVRGQAREQFTGAVDRIFDTAESVCIASVARTVLRAVRDSVVSVARAVWNWIFF"
BASE COUNT          197 a          249 c          268 g          209 t
ORIGIN      
        1 ttccgtctga gtggccacgg tcacagcatg gttatcactg acctgcccgg ggtgggcgag
       61 agccgggaca gggatgcaga gtatgaagcc ctgtaccgtg acattctgcc cgaactggac
      121 ctggtgctgt ggctgattaa agccgatgac cgcgccctgt ctgtggatga gtatttctgg
      181 cgacacatcc tgcaccgggg acatcagcag gtgctgtttg tggtgacgca ggccgacaaa
      241 acggagccct gccatgaatg ggatatggcc ggtattcagc cttctcccgc acaggcacag
      301 aatattcgcg aaaaaacgga ggcggtattc cgtctgttcc ggcccgtaca tccggttgtg
      361 gccgtatcgg cccgcaccgg ctgggaactg gatacgctgg tcagtgcgct catgacagcg
      421 cttcccgacc atgccgccag tcccctgatg acccgcctgc aggacgagct gcgcacggaa
      481 tctgtccggg gtcaggcccg tgaacagttt accggtgcgg tggaccggat atttgacacg
      541 gcggagagcg tctgtattgc ctctgttgca cgcacggttc tgcgggccgt ccgtgactcg
      601 gtggtctctg ttgcccgcgc ggtatggaac tggattttct tctgaacact ctgccagggg
      661 aaatgcctga ttacattgcg ttaaccaact gaaaacatga cacaaacacc tcatacccct
      721 cctgtttctc ttgcgtgacc gctccgctgt caatagaata aaacgatcga taaaacaggt
      781 atcgatcgtc actatcgatc gtttatagtg gttaatggtc tgcgaaaagg cagctgaatc
      841 tcttcattat gcagaacgga attgcacaca acggactgat acttctctgg cggatgagag
      901 aggggaagca tttatgtccg gga
//
LOCUS       DACAOP010000272          913 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.283, whole genome shotgun sequence.
ACCESSION   DACAOP010000272 DACAOP010000000
VERSION     DACAOP010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..913
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.283"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
BASE COUNT          256 a          131 c          163 g          363 t
ORIGIN      
        1 agttgttaag ataaaaatag acaattaagc ctggggtttg aaccatggtt aaggtagcaa
       61 tactattatt tattatgcaa ttaaactcga tgctcgcggt tggtctggga tggttacctc
      121 agagcgttgc attgtctgtg cgagtctgtg tgggaggcta cttactatac cattatatcc
      181 gcaatggtaa gatgcattat tctttatatg cactattatt agtaatgctc acattatttg
      241 ttatcaatga tatgatgttg ataattaatt ttatatttgt aagtttgatg atttattcta
      301 ttaaagataa tggagaggaa tcaatcatca aaagtatcta ttattcgaca attgcattat
      361 cactaatatt tattgtaatc tctctgaatg gtatattaca tcctactatt ctttactctc
      421 ccgatacagg tagatatcga aattcattag ggtttatatc acccaactat cctggattga
      481 ttgctttttc atgcattgtt gcactatttt cttgcattgg aatgttgaaa agtaaagtcg
      541 gaaaaaaaag taaagttctt gtggttataa ttgcattgtt ttgtttggtt ataccgctat
      601 taaccgattc tcgaaccccg ttatatacac taattgtttc atttattttt tatgtattgc
      661 ttagattctc attttttaga ttactaacaa ggatttttat ccctctagta cctgctattt
      721 tcatggggtt aacattatac attgcatttt attacaatca tgatgtaaat gcactattaa
      781 gcggcaggcc gtacttatat tctttatatt tgaaagactt tggttgggtc gattatttat
      841 taggtgggga gggaacccaa ggattttcgg ttgatagttc atacttatta ctattatctt
      901 gttttggtgt gtt
//
LOCUS       DACAOP010000273          893 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.284, whole genome shotgun sequence.
ACCESSION   DACAOP010000273 DACAOP010000000
VERSION     DACAOP010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..893
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.284"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>893
                     /locus_tag="IT892_004670"
     CDS             <1..>893
                     /locus_tag="IT892_004670"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HAP3137768.1"
                     /translation="EYPQSAAIDLRCVNMVADLWHAPAPKNGQAVGTNTIGSSEACML
                     GGMAMKWRWRKRMEAAGKPTDKPNLVCGPVQICWHKFARYWDVELREIPMRPGQLFMD
                     PKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADTGIDIDMHIDAASGG
                     FLAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDEEALPQELVFNVDYL
                     GGQIGTFAINFSRPAGQVIAQYYEFLRLGREGYTKVQNASYQVAAYLADEIAKLGPYE
                     FICTGRPDEGIPAVCFKLKDG"
BASE COUNT          190 a          246 c          258 g          199 t
ORIGIN      
        1 gaatatccgc aatccgcagc catcgacctg cgttgcgtaa atatggttgc cgatctgtgg
       61 catgcgcctg cgccgaaaaa tggtcaggcc gttggcacca acaccattgg ttcttccgag
      121 gcctgtatgc tcggcgggat ggcgatgaaa tggcgttggc gcaagcgtat ggaagctgca
      181 ggcaaaccaa cggataaacc aaacctggtg tgcggtccgg tacaaatctg ctggcataaa
      241 ttcgcccgct actgggatgt ggagctgcgt gagatcccta tgcgccccgg tcagttgttt
      301 atggacccga aacgcatgat tgaagcctgt gacgaaaaca ccatcggcgt ggtgccgact
      361 ttcggcgtga cctacaccgg taactatgag ttcccacaac cgctgcacga tgcgctggat
      421 aaattccagg ccgacaccgg tatcgacatc gacatgcaca tcgacgctgc cagcggtggc
      481 ttcctggcac cgttcgtcgc cccggatatc gtctgggact tccgcctgcc gcgtgtgaaa
      541 tcgatcagtg cttcaggcca taaattcggt ctggctccgc tgggctgcgg ctgggttatc
      601 tggcgtgacg aagaagcgct gccgcaggaa ctggtgttca acgttgacta cctgggtggt
      661 caaattggta cttttgccat caacttctcc cgcccggcgg gtcaggtaat tgcacagtac
      721 tatgaattcc tgcgcctcgg tcgtgaaggc tataccaaag tacagaacgc ctcttaccag
      781 gttgccgctt atctggcgga tgaaatcgcc aaactggggc cgtatgagtt catctgtacg
      841 ggtcgcccgg acgaaggcat cccggcggtt tgcttcaaac tgaaagatgg tga
//
LOCUS       DACAOP010000274          892 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.285, whole genome shotgun sequence.
ACCESSION   DACAOP010000274 DACAOP010000000
VERSION     DACAOP010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..892
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.285"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..665
                     /gene="rfaY"
                     /locus_tag="IT892_004671"
     CDS             <1..665
                     /gene="rfaY"
                     /locus_tag="IT892_004671"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II) kinase RfaY"
                     /protein_id="HAP3137769.1"
                     /translation="FTDENNSKYLNVLNDFLSYDINIIKVFRSIDDTKVMLIDTDYGK
                     LILKVFSPKVKRNERFFKSLLKGDYYERLFEHTQKVRNEGLHSLNDFYLLAERKTLRF
                     VHTYIMLIEYIDGVELCDIPDIDETLKNKIQQSIRSLHEHGMVSGDPHRGNFIIENGE
                     VRIIDLSGKRASAQRKAKDRIDLERHYGIKNEVKDLGYYLLVYRKKIRNLMRRLKGKP
                     AR"
BASE COUNT          293 a          141 c          161 g          297 t
ORIGIN      
        1 tttttaccga tgaaaataac tcaaagtatc tcaatgtatt aaatgacttt ctttcttatg
       61 atattaatat catcaaagtt tttcgttcta tagatgatac aaaagtcatg cttattgata
      121 ccgattacgg taaattgata cttaaagttt tttcgcctaa agtaaaacgc aacgaacgtt
      181 tctttaaatc tcttttaaag ggagattatt atgaacgcct ttttgagcat actcaaaaag
      241 tgcgtaacga ggggctacat tctctcaatg atttttattt gttggcagaa cggaaaacat
      301 tacgttttgt ccatacttat atcatgctta tcgaatatat cgatggcgta gagttgtgtg
      361 atatccccga tattgatgaa actttaaaaa ataaaattca acaatcaatt cgttcattac
      421 acgaacacgg tatggtatct ggtgatcctc accgcggtaa ttttattatt gaaaatggtg
      481 aagtacgcat tattgatctt tcaggaaaac gggcatctgc acaacgtaaa gcgaaagatc
      541 gtattgattt agagcgacat tatggtatta agaatgaggt taaagatctc ggttattatc
      601 ttttagttta tcgtaaaaaa atacgtaatc ttatgcggcg tttgaaaggg aagccagcac
      661 gataaagtaa aagtcttaca tttaaacgtc ttcgtcagga catttctatg cggagttctt
      721 atttcacagg tttatcatga agaatattag atacattgac aaaaaagatg ttgaaaacct
      781 gatagaaagt aaaacgtctg atgatgttat tatttttctt tccggcccca catcgcaaaa
      841 aacaccattg tcagtgctgc agacaaggga tgttattgct gtcaatggtt ct
//
LOCUS       DACAOP010000275          864 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.286, whole genome shotgun sequence.
ACCESSION   DACAOP010000275 DACAOP010000000
VERSION     DACAOP010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..864
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.286"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>864
                     /locus_tag="IT892_004672"
     CDS             <1..>864
                     /locus_tag="IT892_004672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HAP3137770.1"
                     /translation="LNGGEQWVHEGGIATGTVINEKGWQAVKSGAVATDTVVNTGAEG
                     GPDAENGDTGQTVYGDAVRTTINKNGRQIVAAEGTANTTVVYAGGDQTVHGHALDTTL
                     NGGYQYVHNGGTASGTVVNSDGWQIIKEGGLADFTTVNQKGKLQVNAGGTATNVTLTQ
                     GGALVTSTAATVTGSNRLGNFTVENGKADGVVLESGGRLDVLEGHSAQKTLVDDGGTL
                     AVSAGGKATDVTMTSGGALIADSGATVEGTNASGKFSIDGISGQASGLLLENGGSFTV
                     NTGGQAGNTTVG"
BASE COUNT          206 a          211 c          291 g          156 t
ORIGIN      
        1 ctgaacggcg gtgagcagtg ggtacatgaa ggcgggattg caacgggtac cgtcattaat
       61 gagaagggct ggcaggccgt caaatccggc gcagtggcaa ccgacacggt tgtgaatacc
      121 ggcgcggaag ggggaccgga tgcggaaaat ggtgataccg ggcagaccgt ctacggagat
      181 gccgtacgca ccaccatcaa taaaaatggt cgtcagattg tggctgctga aggaacggca
      241 aataccactg tggtttatgc cggcggcgac cagactgtac atggtcacgc actggatacc
      301 acgctgaatg gggggtacca gtatgtgcac aacggcggta cggcgtctgg cactgttgtt
      361 aacagtgacg gctggcagat tatcaaggaa ggtggtctgg cggatttcac caccgttaac
      421 cagaaaggca aactgcaggt gaacgccggt ggtacagcca cgaatgtcac cctgacgcag
      481 ggcggcgcac tggtcaccag tacggcggca accgtcaccg gtagcaaccg tctgggcaat
      541 ttcacggtgg aaaacggtaa ggctgacggc gttgttctgg agtccggcgg tcgcctggat
      601 gtactggagg gccattcagc gcagaaaaca ctggtggatg acggcggtac cctggcagtg
      661 tctgccggtg gtaaggcaac agatgtcacc atgacatccg gtggtgccct gatagcagac
      721 agtggtgcca ctgttgaggg gaccaatgcc agcggtaagt tcagtattga tggcatatcc
      781 gggcaggcca gcggcctgct actggaaaat ggcggcagct ttacggttaa taccggggga
      841 caggcaggca acaccactgt cgga
//
LOCUS       DACAOP010000276          858 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.287, whole genome shotgun sequence.
ACCESSION   DACAOP010000276 DACAOP010000000
VERSION     DACAOP010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.287"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>858
                     /gene="treA"
                     /locus_tag="IT892_004673"
     CDS             <1..>858
                     /gene="treA"
                     /locus_tag="IT892_004673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="alpha,alpha-trehalase TreA"
                     /protein_id="HAP3137771.1"
                     /translation="EKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVV
                     PGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRS
                     QPPFFALMVELLAQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGT
                     LLNRYWDDRDTPRPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQ
                     QLNTLRTTSIVPVDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYLW
                     NDQQGWYAD"
BASE COUNT          234 a          225 c          220 g          179 t
ORIGIN      
        1 gtgagaaata tgttccgcca gaggggcagt cactgcgcga acatattgac ggactttggc
       61 cggtattaac gcgttctacc gaaaacaccg aaaaatggga ttctctgtta ccgctgccgg
      121 aaccttatgt cgtgccgggc ggacgctttc gcgaggtata ttactgggac agttacttca
      181 ccatgttagg acttgccgaa agcggtcact gggataaagt cgcggatatg gtggccaatt
      241 ttgctcatga aatagacact tacggtcata ttcccaacgg caaccgcagt tactatttaa
      301 gccgctcgca accgcccttc tttgccctga tggtagagtt actggcgcag catgaaggcg
      361 atgccgcgtt gaagcaatac ctgccgcaaa tgcaaaaaga atatgcttac tggatggacg
      421 gtgttgaaaa cctgcaagcc ggacaacagg aaaaacgcgt tgtcaaactt caggatggta
      481 cccttctcaa ccgctactgg gacgatcgcg atacgccacg accagagtca tgggtggaag
      541 atattgccac cgccaaaagc aatccgaatc gacctgccac tgaaatttac cgcgacctgc
      601 gctctgccgc tgcgtctggc tgggatttca gctcgcgctg gatggacaac ccgcagcagt
      661 taaatacctt acgcaccacc agcatcgtac cggtcgatct gaacagcctg atgtttaaaa
      721 tggaaaaaat cctcgcccgc gccagcaaag ctgccggaga taacgcgatg gcaaaccagt
      781 acgaaacgct ggcaaatgcc cgtcaaaaag ggatcgaaaa atacctgtgg aacgatcaac
      841 aaggctggta tgccgatt
//
LOCUS       DACAOP010000277          856 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.288, whole genome shotgun sequence.
ACCESSION   DACAOP010000277 DACAOP010000000
VERSION     DACAOP010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..856
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.288"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>856
                     /locus_tag="IT892_004674"
     CDS             <1..>856
                     /locus_tag="IT892_004674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001271524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HAP3137772.1"
                     /translation="VTCPADPGKLSPEELKRLPSECSPLVEQNLMPWLSTGAAALITA
                     LAVVELNDDDDHHHRNNSPLPPTPPDDESDDTPVPPTPGGDEIIPDDPDDTPTPPKPV
                     SFNNDVILDKTEKTLTIRDSVFTYTENADGTISLQDSNGRKATINLWQIDEANNTVAL
                     EGVSADGATKWQYNHNGELVITGDNATVNNNGKTTVDGKDSTGTEINGNNGKVIQDGD
                     LDVSGGGHGIDITGDSATVDNKGTMTVTDPESMGIQIDGDKAIVNNEGESTITNGGTG
                     TQINGDDAT"
BASE COUNT          250 a          217 c          210 g          179 t
ORIGIN      
        1 gtgacttgtc cggcagaccc aggaaaactc agtccggaag agcttaaacg cttaccctct
       61 gaatgctctc ctttagtcga acaaaacctg atgccatggc tttccacagg cgctgctgcg
      121 ttaatcacgg ccttagccgt agtggaacta aacgacgatg atgatcatca tcatcgcaac
      181 aattctccac tcccaccgac accccctgat gatgaatcag acgacactcc agttccccca
      241 actcctggcg gagatgagat aataccggac gatccggatg atacgcctac acctcccaaa
      301 ccggtttcgt ttaataatga cgttattctc gataaaacag aaaaaacgtt aactattcgc
      361 gattcagttt ttacttatac cgagaatgct gacgggacta tatctctgca agatagcaat
      421 ggtcgtaagg caacgattaa tctttggcag attgatgaag cgaataacac tgttgccctt
      481 gaaggggtga gcgcagatgg cgcaacgaag tggcaatata atcacaacgg tgagcttgtt
      541 attacgggtg ataatgccac agtaaacaac aatggcaaaa ccaccgttga cggtaaagat
      601 tccaccggta cggaaatcaa cggtaataac gggaaagtga ttcaggacgg cgatctggat
      661 gtcagcggcg gcggtcacgg tattgatatc accggtgaca gcgcgacggt ggataacaag
      721 ggcaccatga ccgtcaccga tccggagtcc atgggtatcc agatcgacgg tgacaaggcc
      781 atcgtcaata acgaaggcga gagcaccatc accaacggtg gcaccggcac ccagattaat
      841 ggtgatgacg ccacgg
//
LOCUS       DACAOP010000278          838 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.289, whole genome shotgun sequence.
ACCESSION   DACAOP010000278 DACAOP010000000
VERSION     DACAOP010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.289"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(478..585)
                     /locus_tag="IT892_004675"
     CDS             complement(478..585)
                     /locus_tag="IT892_004675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small toxic polypeptide LdrA/LdrC"
                     /protein_id="HAP3137773.1"
                     /translation="MTLAQFAMIFWHDLAAPILAGIITAAIVSWWRNRK"
BASE COUNT          182 a          227 c          198 g          231 t
ORIGIN      
        1 ggtgccgcca ggtcgtgcca gaaagtcatg gcaaactgcg cgagcgtcat atagccgcct
       61 tgttgtaatg acaacatttt gcggctattc ttgaagtgtc tggtttcaag attagccccc
      121 gttctgttgt caggttttac ctctcaacgt gcgggggttt tctctttcca gcaaccaatg
      181 ccaccaggga taaagccccc gcaacattgc gcctcaccgg ataattccgg cttggtgtgg
      241 atactacgtc tcaattcatc ttcacttcat ccctgaaatg tttgcaataa agagtacatt
      301 ccggcttttc aacagctgtt gcagtcgttt catgagtgct ctggatgatg cttccagctc
      361 gggttgccaa tatttacttg tggaagagat aaagacaaaa atggccgcag gctgttaccc
      421 ctgcggccgg tttcgggcgc atattgccat cacggcagcc tgacgcccgt tttcacctta
      481 cttccggtta cgccaccagc tgacaatcgc tgcggtaata attcccgcca ggatcggtgc
      541 tgccaggtcg tgccagaaaa tcatggcaaa ctgcgcgagc gtcatatagc cgccttgttg
      601 taatgacaac attttgcggc tattcttgaa ttgttctggt tcaagattag cccccgttct
      661 gttgtcaggt tgtacctctc aacgtgcggg ggttttctct ttccagcaac caatgccacc
      721 agggataaag cccccgcaac attgcgcctc accggataac gccggcttgg tgtggatact
      781 acgactcaat tcatcttcac ttcatccctg aaatgtttgc aatgaagagt gcattccg
//
LOCUS       DACAOP010000279          836 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.290, whole genome shotgun sequence.
ACCESSION   DACAOP010000279 DACAOP010000000
VERSION     DACAOP010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..836
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.290"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            1..836
                     /locus_tag="IT892_004676"
                     /pseudo
     CDS             1..836
                     /locus_tag="IT892_004676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558234.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          240 a          196 c          227 g          173 t
ORIGIN      
        1 ggcactggat tgcagacaca agcgtagcta ttctcctgaa gataaacttt gcgtggttct
       61 ttatgctctc gggcattctg agtctctacc ccgggtagct gcccggttta acattcccag
      121 ccacaacacg gttaaaaact ggataaaagg ctaccgcaaa tctggtaatg aggcctttat
      181 caggcgcagg aaggagaaaa gcatgacccg ttctgatgat acccatgaaa acgaggcaaa
      241 catgacgccg gaagagatga agaatgagct acgttatctt cgcgcagaaa atgcatatct
      301 gaaagccatg caggagcatc tcctggaaaa aaagcgccag gagctggaga aaaaacgaaa
      361 gtcatccgga gcctgaggtg cggacactgc cagtctgacc tgttaaaggc tgcagggctg
      421 gccagaagca cgctgtacta ccagctgtca ctgcagaagg ctaaggacaa gtatgctgat
      481 gtgaaacagc tcatagcctc catcttccat gaacaccggg gatgttatgg gtaccggcgg
      541 atccattgtg agcttcagaa aagaggtctt aagttcagtg gcaaaacggt gcgaaaactg
      601 atgcaacagc tcggcctgaa gtctcctgtg cgcctgaaga aataccggtc ttaccgggga
      661 aatatgggac tcgctgcaga aaatatcctt cagcggcagt tcaaagcgga agctccctgt
      721 gagaaatggg tgacagatat caccgaattc agggctggcg gacaaaaact gtacctgtcc
      781 ccgatacttg atttgtttaa cggggaaatc gtggcgtggg aaactgcctg caggcc
//
LOCUS       DACAOP010000280          833 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.291, whole genome shotgun sequence.
ACCESSION   DACAOP010000280 DACAOP010000000
VERSION     DACAOP010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..833
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.291"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>833
                     /locus_tag="IT892_004677"
     CDS             <1..>833
                     /locus_tag="IT892_004677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HAP3137774.1"
                     /translation="IINENEFWGLASQILNWEWPEDSLSLLKNLDIEEENVGLPQGLA
                     SAGALANAYLIEFDESLTSNLRTKIDGSQIVLHDYCRYVDDIRLVISGEALTNEEIKK
                     SIHELVQRILDETLDQDESDNEPYLKINDKKTYILGLSDIDNGSSLTNRINEIQNEVG
                     TSSIPERNGLDNNIPALQQLLLTEQDNFLEDADGLFSGFNNDKSIKLESLRRFSAHRL
                     ETSLANKSKLISPAERKQFDNESALIAKKLLKTWLKDPSIMVIFRKAITINPNLDAYK
                     T"
BASE COUNT          300 a          122 c          158 g          253 t
ORIGIN      
        1 attataaatg agaatgagtt ttggggttta gcgagtcaga ttttaaattg ggagtggcct
       61 gaagactctt tatctttact taaaaatttg gatattgaag aagaaaatgt tggactccca
      121 caaggtttag catctgccgg agctttggct aatgcatatc tcattgagtt tgacgaatct
      181 ttaacttcta acctccgtac taagatagac ggtagccaaa ttgtactgca tgattattgt
      241 cgatacgtcg atgatattag attggtgatt tctggagaag cattaacaaa tgaggaaatt
      301 aagaaatcca ttcatgagtt agttcagagg atcctcgatg aaacgttaga tcaagatgag
      361 tcagataacg aaccatattt aaaaattaat gataaaaaaa cttatatatt gggactctca
      421 gatattgata acggaagtag ccttacaaat cgaatcaatg aaatccagaa tgaagtagga
      481 acttcgagta ttccagagcg taatggatta gataataaca taccggcgct tcaacaatta
      541 ttattgactg agcaagataa ttttttagaa gatgcagatg gtttattttc tggatttaac
      601 aatgataaat cgattaaatt agaatcttta cgtagatttt ctgcccatag gctggaaaca
      661 agtttggcta ataaaagcaa actaatctca cctgcagaaa gaaagcagtt tgataatgaa
      721 tctgcgttga ttgcaaaaaa attattaaaa acctggttaa aagatccatc aattatggtt
      781 attttccgca aagcgataac cataaaccct aatctagatg cttataaaac aat
//
LOCUS       DACAOP010000281          766 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.293, whole genome shotgun sequence.
ACCESSION   DACAOP010000281 DACAOP010000000
VERSION     DACAOP010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.293"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            15..731
                     /locus_tag="IT892_004678"
     CDS             15..731
                     /locus_tag="IT892_004678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP3137775.1"
                     /translation="MGRKWANIVAKKTAKDGATSKIYAKFGVEIYAAAKQGEPDPELN
                     TSLKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMIIAETLTSN
                     VNRTIANVRTIFNKKGGNIGAAGSVSYMFDNTGVIVFKGTDPDHIFEILLEAEVDVRD
                     VTEEEGNIVIYTEPTDLHKGIAALKAAGITEFSTTELEMIAQSEVELSPEDLEIFEGL
                     VDALEDDDDVQKVYHNVANL"
BASE COUNT          254 a          129 c          167 g          216 t
ORIGIN      
        1 aggagatcat tccagtggga cgtaaatggg ccaatattgt tgctaaaaaa acggctaaag
       61 acggtgcaac gtctaaaatt tatgcaaaat tcggtgtaga aatctatgct gctgccaaac
      121 aaggtgaacc cgatccagaa ttaaacacat ctttaaaatt cgttattgaa cgtgcaaagc
      181 aggcacaagt tccaaagcac gttattgata aagcaattga taaagccaaa ggcggcggag
      241 atgaaacgtt cgtacaggga cgttatgaag gctttggtcc taatggctca atgattattg
      301 ctgagacatt gacttcaaat gttaaccgta cgattgctaa cgttcgcaca attttcaata
      361 aaaaaggcgg caatatcgga gcggcaggtt ctgtcagcta tatgtttgac aatacgggtg
      421 tgattgtatt taaaggaaca gaccctgacc atatttttga aattttgctt gaagctgaag
      481 ttgatgttcg tgatgtaact gaagaagaag gtaatattgt tatttatact gaacctactg
      541 accttcataa aggaatcgcg gcgctaaaag cagctggaat cactgagttc tcaacaacag
      601 aattagaaat gattgctcaa tctgaagttg agctttcccc agaagattta gaaatctttg
      661 aagggcttgt tgatgccctt gaagatgacg acgatgtaca aaaagtttat cataacgttg
      721 caaatctcta attatatttt aaagaaatct gtctttatgg cagatt
//
LOCUS       DACAOP010000282          759 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.294, whole genome shotgun sequence.
ACCESSION   DACAOP010000282 DACAOP010000000
VERSION     DACAOP010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.294"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
BASE COUNT          146 a          232 c          186 g          195 t
ORIGIN      
        1 ctttgatgaa agcgtgatcc gcgccgcttc agccagccat tctggttgtg ttatcagacg
       61 cagcagccgt tgaatccgta gggacggatc ggtgactgcc catgtggcaa gcttgcgttg
      121 catttcgctg attatcaaag gtcttcacct cgttaggtca gttaattcac gtcgcaaaca
      181 cattcaaact gcttcccttc gccatgtaat gggctttccc catcgcggac tactacggaa
      241 gctccgccag ccagcgcgtc atcggagcca tgccccctta acatccgtcg ctgaccttcc
      301 ccggtttacc tgcctggact caggcatact gaggaggctg cccgtcgcac tctttatcct
      361 tgcttgccgc aagttggcag aagtcagcaa cgcaagcgtg atagacgctg ctgccccggt
      421 gtttcgcata catgtcaaaa caccttcgac cggcagtgct tacgtatcac tgccagttcc
      481 tcctgcacgg cctgtcagat cacgtaggcc gtggtgacgt tttcaaccca cagaggcgga
      541 ttaacgggtt catgttcttc agcctttcag tacttaacct tgaggatcat ctcggcttag
      601 tgatctcgcc tcaatccccg ttgtcagcgg gttacatcac cctgcgggca tgccgcaggt
      661 cactgccgct caggttctcc accgtcacac ccggtgggat tgttgggttt ctcatcgtga
      721 gttaccggct caatattcca gacagactcg cggttcatt
//
LOCUS       DACAOP010000283          753 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.295, whole genome shotgun sequence.
ACCESSION   DACAOP010000283 DACAOP010000000
VERSION     DACAOP010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..753
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.295"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            34..753
                     /locus_tag="IT892_004679"
                     /pseudo
     CDS             34..753
                     /locus_tag="IT892_004679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          189 a          186 c          223 g          155 t
ORIGIN      
        1 gagactaaac ttcctgagaa agaggtaaac aggatgacta aaaatactcg tttttccccc
       61 gaagtccgtc aacgggcagt ccgtatggtt ctggaaagtc agagcgaata tgactcacaa
      121 tgggcgacaa tttgttccat tgctccaaag attggctgta cgccggagac tctgcgtgtc
      181 tgggttcgcc agcatgagcg ggataccggg ggcggtgatg gagggctcac caccgctgaa
      241 cgtcagcgtc tgaaagagct ggaacgtgaa aatcgtgaac tgcgccgcag taacgatatc
      301 cttcgccagg cttccgctta ttttgcgaag gcggagttcg accgcctctg gaaaaaatga
      361 tgccactgct ggataagctg cgtgagcagt acggggtcgg accgctatgc agcgaactgc
      421 atattgcccc gtcaacgtat taccactgtc agcaacagcg acatcatccg gataaacgca
      481 gtgcccgtgc gcagcgcgat gactggctga agaaagagat acagcgcgta tacgatgaaa
      541 atcacaaggt atacggtgtg cgtaaagtct ggcgtcagtt gttacgggaa ggtatcagag
      601 tggccagatg cactgtggca cgtctcatgg cggttatggg acttgccggt gttctccggg
      661 gtaaaaaggt ccgtacgacc atcagccgga aagccgttgc cgcaggcgac cgcgtaaacc
      721 gtcagttcgt ggcagaacga cctgaccagc tgt
//
LOCUS       DACAOP010000284          694 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.296, whole genome shotgun sequence.
ACCESSION   DACAOP010000284 DACAOP010000000
VERSION     DACAOP010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.296"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>694
                     /locus_tag="IT892_004680"
     rRNA            <1..>694
                     /locus_tag="IT892_004680"
                     /product="16S ribosomal RNA"
BASE COUNT          176 a          156 c          229 g          133 t
ORIGIN      
        1 tagctggtct gagaggatga ccagccacac tggaactgag acacggtcca gactcctacg
       61 ggaggcagca gtggggaata ttgcacaatg ggcgcaagcc tgatgcagcc atgccgcgtg
      121 tatgaagaag gccttcgggt tgtaaagtac tttcagcggg gaggaaggga gtaaagttaa
      181 tacctttgct cattgacgtt acccgcagaa gaagcaccgg ctaactccgt gccagcagcc
      241 gcggtaatac ggagggtgca agcgttaatc ggaattactg ggcgtaaagc gcacgcaggc
      301 ggtttgttaa gtcagatgtg aaatccccgg gctcaacctg ggaactgcat ctgatactgg
      361 caagcttgag tctcgtagag gggggtagaa ttccaggtgt agcggtgaaa tgcgtagaga
      421 tctggaggaa taccggtggc gaaggcggcc ccctggacga agactgacgc tcaggtgcga
      481 aagcgtgggg agcaaacagg attagatacc ctggtagtcc acgccgtaaa cgatgtcgac
      541 ttggaggttg tgcccttgag gcgtggcttc cggagctaac gcgttaagtc gaccgcctgg
      601 ggagtacggc cgcaaggtta aaactcaaat gaattgacgg gggcccgcac aagcggtgga
      661 gcatgtggtt taattcgatg caacgcgaag aacc
//
LOCUS       DACAOP010000285          680 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.297, whole genome shotgun sequence.
ACCESSION   DACAOP010000285 DACAOP010000000
VERSION     DACAOP010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..680
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.297"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            1..219
                     /locus_tag="IT892_004681"
     CDS             1..219
                     /locus_tag="IT892_004681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001520354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP3137776.1"
                     /translation="MTGENRGRGRPRKTESTYADTRNDLIRSGLELLTQNGFLATGVD
                     AIVKNANVPKGSFYYYLKSKEDYAVNDG"
     gene            complement(270..659)
                     /locus_tag="IT892_004682"
     CDS             complement(270..659)
                     /locus_tag="IT892_004682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011566155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP3137777.1"
                     /translation="MRCSVDAYADLLLQLSTAQRQGRYKTTLQRGVMAPRLLIIDEIG
                     YLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDAALTSAMLDRILHHS
                     HIVQIKGESYRLRQKRKAGVIAEANPE"
BASE COUNT          171 a          156 c          170 g          183 t
ORIGIN      
        1 atgacaggcg aaaatcgtgg ccggggaagg ccgcgaaaga cagaaagtac ctatgcagat
       61 actcgtaatg atctgatccg cagtggcctt gaactgctga cgcagaatgg ttttcttgcg
      121 acgggagtcg atgccattgt taaaaatgcc aatgtcccta aaggctcatt ttattactac
      181 cttaagagta aagaggatta tgctgtcaac gacggatgaa aagtgatcca cttatatctc
      241 caccaacggc ccaatattga tccaccgttt tactcaggat tagcttctgc tataaccccg
      301 gcctttcgtt tctgtctgag tcgatagctt tctcctttga tttgaacgat atgtgagtgg
      361 tgtaagatac ggtccagcat cgctgaggtc agtgctgcat caccggcgaa cgtttgatcc
      421 cactgcccga acggcagatt ggatgtcagg atcattgcgc tcttttcgta acgtttagcg
      481 atgacctgga agaacagctt tgcttcttcc tgactgaacg gcagatagcc tatttcatca
      541 atgatgagca ggcggggggc cattactcca cgctgaagcg tcgttttata acggccctga
      601 cgttgtgccg tagataactg aagtaacaga tctgcgtaag cgtcaacgga gcaccgtatt
      661 gacgcttatt tattggtgag
//
LOCUS       DACAOP010000286          630 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.298, whole genome shotgun sequence.
ACCESSION   DACAOP010000286 DACAOP010000000
VERSION     DACAOP010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.298"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>630
                     /locus_tag="IT892_004683"
     rRNA            <1..>630
                     /locus_tag="IT892_004683"
                     /product="23S ribosomal RNA"
BASE COUNT          143 a          143 c          204 g          140 t
ORIGIN      
        1 cgccagtctg catggagccg accttgaaat accacccttt aatgtttgat gttctaacgt
       61 tgacccgtaa tccgggttgc ggacagtgtc tggtgggtag tttgactggg gcggtctcct
      121 cctaaagagt aacggaggag cacgaaggtt ggctaatcct ggtcggacat caggaggtta
      181 gtgcaatggc ataagccagc ttgactgcga gcgtgacggc gcgagcaggt gcgaaagcag
      241 gtcatagtga tccggtggtt ctgaatggaa gggccatcgc tcaacggata aaaggtactc
      301 cggggataac aggctgatac cgcccaagag ttcatatcga cggcggtgtt tggcacctcg
      361 atgtcggctc atcacatcct ggggctgaag taggtcccaa gggtatggct gttcgccatt
      421 taaagtggta cgcgagctgg gtttagaacg tcgtgagaca gttcggtccc tatctgccgt
      481 gggcgctgga gaactgaggg gggctgctcc tagtacgaga ggaccggagt ggacgcatca
      541 ctggtgttcg ggttgtcatg ccaatggcac tgcccggtag ctaaatgcgg aagagataag
      601 tgctgaaagc atctaagcac gaaacttgcc
//
LOCUS       DACAOP010000287          629 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.299, whole genome shotgun sequence.
ACCESSION   DACAOP010000287 DACAOP010000000
VERSION     DACAOP010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..629
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.299"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            292..396
                     /locus_tag="IT892_004684"
                     /pseudo
     CDS             292..396
                     /locus_tag="IT892_004684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          211 a          125 c          120 g          173 t
ORIGIN      
        1 tcaaagctat catacagata attactggtt aaccctatat agggcatttt aaagtgttgt
       61 gatcttaccc agcaatagtg gacacgcggc taagtgagta aactctcagt cagaggtgac
      121 tcacaagaca aaacagtttc aaccagtaaa aaaacgtaaa caccattcgc atgaatttcg
      181 tagttaagat ctgaagcttg cagaatgcat cggtgttact gccggagtcc gtgaacttag
      241 tctgcatgaa tcaccacagc tttacatctg tcgcagtaaa cagcaaaatc agcaaactta
      301 cttaattata tcgagtgcga ttacaatcgc tggcgatggt acagttggtg tggcggtctc
      361 agtccggaac aatttgaaaa tcagaatctc acttaaaacg gcatccattt tacaaaagat
      421 ggccgtctgt gtatttataa tgaatacctt ctacatgttt agagtgcata atccacgaca
      481 aggcgatatc ctaaaaatta gctagcaggc aactttgatg gcatagataa tgtttttagt
      541 aaaaaagagt tgacttaata taatacagcc tcttcctaca taagaaggaa tgtgctcaca
      601 aaaaaaaacc attagtctgc ttcctgttc
//
LOCUS       DACAOP010000288          609 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.300, whole genome shotgun sequence.
ACCESSION   DACAOP010000288 DACAOP010000000
VERSION     DACAOP010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..609
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.300"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(339..578)
                     /locus_tag="IT892_004685"
     CDS             complement(339..578)
                     /locus_tag="IT892_004685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase V"
                     /protein_id="HAP3137778.1"
                     /translation="MPRHYEIDSAWRASIKREPNGRQTVTTEAFVSQLALINFHWSCR
                     QANQWIETYVTVFKDISTQEGENRTFMLFNPNGGR"
BASE COUNT          152 a          162 c          140 g          155 t
ORIGIN      
        1 aatgtgcgta atgacccccc tgacctccaa cccgtcctca tcgtcatcag gtatagccct
       61 gaagttatcc agcttatcga gttcctggag acaccgcttg gggtgtagtc gcaatcgcat
      121 gatcctgaat tcttgttcca ggacacagag caccaaagac ccgtcaacgg gcgtgccccc
      181 aaaatctact atgagcagcg caccaggctt tatcccttcc cggaaagagt aggtatcact
      241 tcgaaaaaag aatactcccg gcgctcctgt attacagtgc tgatcgagtg acagcctgtt
      301 ttcctggtag tcggttgctg gcgatggaaa acccattttt aacggcctcc gttggggtta
      361 aaaagcatga atgtccggtt ctctccttcc tgagtggaaa tgtctttaaa aacggtcacg
      421 taggtttcaa tccactgatt tgcttggcga caactccagt gaaaattaat cagcgcaagc
      481 tggctgacaa aggcttctgt cgtaactgtc tgacgaccgt tcggctcacg cttaatgctc
      541 gcacgccagg ctgagtcaat ttcatagtgt ctaggcatga aaaacctccg atcaatatag
      601 ctgtatgca
//
LOCUS       DACAOP010000289          561 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.302, whole genome shotgun sequence.
ACCESSION   DACAOP010000289 DACAOP010000000
VERSION     DACAOP010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.302"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(51..386)
                     /locus_tag="IT892_004686"
     CDS             complement(51..386)
                     /locus_tag="IT892_004686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004856597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phnA family protein"
                     /protein_id="HAP3137779.1"
                     /translation="MSLPHCPKCNSEYTYEDNGMYICPECAYEWNDAEPAQESDELIV
                     KDANGNLLADGDSVTIIKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMK
                     LKSEFVKKN"
BASE COUNT          139 a          130 c          127 g          165 t
ORIGIN      
        1 ttgccggatg cggcgcgagc gccttatccg gcttaccgat cacaatacaa tcagttcttt
       61 ttcacaaact cagatttcag tttcatcgga ccaaaaccgt cgattttgca atcgatgtta
      121 tggtcgcctt caaccaggcg gatgtttttc actttggtgc caattttcag catcgaagag
      181 ctacctttca ccttcagatc tttaatgatg gtaacgctgt cgccgtcagc cagcagattg
      241 ccgttagcat ctttaacgat cagctcgtcg ctttcctgtg caggttctgc gtcgttccat
      301 tcgtaggcac attccgggca gatgtacatg ccgttatctt cgtaggtgta ttcggagttg
      361 cattttgggc agtgtggtaa tgacatgtgg atttcctcaa aagtcagcag ggcaaaagcg
      421 ccaaaaaacg gcagattgcc gaaaaaggcc gcaattatac acaaaatccc tgagtttgtc
      481 gggggtactg ctgattttag acgacgatcg ttttcatttg aaaggaaacg caaaaagaaa
      541 ataatctttt tgcctctatt t
//
LOCUS       DACAOP010000290          542 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.303, whole genome shotgun sequence.
ACCESSION   DACAOP010000290 DACAOP010000000
VERSION     DACAOP010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.303"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>542
                     /locus_tag="IT892_004687"
     CDS             <1..>542
                     /locus_tag="IT892_004687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element ISVsa5 family transposase"
                     /protein_id="HAP3137780.1"
                     /translation="VALHGRSVTLYEKAFPLSEQCSKKAHDQFLADLASILPSNTTPL
                     IVSDAGFKVPWYKSVEKLGWYWLSRVRGKVQYADLGAENWKPISNLHDMSSSHSKTLG
                     YKRLTKSNPISCQILLYKSRSKGRKNQRSTRTHCHHPSPKIYSASAKEPWVLATNLPV
                     EIRTPKQLVNIYSKRMQIEET"
BASE COUNT          172 a          127 c          109 g          134 t
ORIGIN      
        1 gtcgcactac acggtcgttc tgttactctt tatgagaaag cgttcccgct ttcagagcaa
       61 tgttcaaaga aagctcatga ccaatttcta gccgaccttg cgagcattct accgagtaac
      121 accacaccgc tcattgtcag tgatgctggc tttaaagtgc catggtataa atccgttgag
      181 aagctgggtt ggtactggtt aagtcgagta agaggaaaag tacaatatgc agacctagga
      241 gcggaaaact ggaaacctat cagcaactta catgatatgt catctagtca ctcaaagact
      301 ttaggctata agaggctgac taaaagcaat ccaatctcat gccaaattct attgtataaa
      361 tctcgctcta aaggccgaaa aaatcagcgc tcgacacgga ctcattgtca ccacccgtca
      421 cctaaaatct actcagcgtc ggcaaaggag ccatgggttc tagcaactaa cttacctgtt
      481 gaaattcgaa cacccaaaca acttgttaat atctattcga agcgaatgca gattgaagaa
      541 ac
//
LOCUS       DACAOP010000291          525 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.304, whole genome shotgun sequence.
ACCESSION   DACAOP010000291 DACAOP010000000
VERSION     DACAOP010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.304"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
BASE COUNT          175 a           74 c          124 g          152 t
ORIGIN      
        1 gttttatttt taatgaggaa acattgtatt ttactgtttt tggtggggat tttattatgg
       61 atgatttaaa aaaagtaaaa aatacggaag catgggtatg gtataaaaat tgcgatagta
      121 aaaataaaaa tgtggcagtt gaacttcttc aaatctacga attgcatcaa tgaaaaatat
      181 agttaaatag aggaggttat taatagcagg aaaagcatca cgtgatgctg attttttgca
      241 ctaaataatt cgcgctaatg ttcaatagtt aatatatccc tcatcaggga aagatcaccg
      301 gtgtgccgta ggcacaaaga tgcaaaacgg gacgttttgc atgtaataag cataagcttg
      361 tgaagagatg gtggcaggcc caccgggatc tgctgtcgga agtcggtccc aaacaacccc
      421 ggctgctgtg gtaaagagcc atggtagtga gcgcaggggc agggaaagat cacgtaacgc
      481 tgattttttg tactaaataa ttcgcatttt atgtttaaaa attga
//
LOCUS       DACAOP010000292          488 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.305, whole genome shotgun sequence.
ACCESSION   DACAOP010000292 DACAOP010000000
VERSION     DACAOP010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.305"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(265..>488)
                     /locus_tag="IT892_004688"
     CDS             complement(265..>488)
                     /locus_tag="IT892_004688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308434.1"
                     /note="catalyzes the formation of pyruvate and
                     acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved
                     in the degradation of phenylpropionate; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="HAP3137781.1"
                     /translation="VRPLQDRPVRVDRETLALGYAGVYSSFLRHCETAAARYGLSAVD
                     ILVELGKRRMVGGQEDMIVDVALDLRNNK"
BASE COUNT          107 a          164 c          123 g           94 t
ORIGIN      
        1 acgccgcatc cggcagtcgt gcgcagatgc ctgatgcgac gctaacgcgt cttatcaggc
       61 ctacaaattc ccgcgccatc cgtaggccgg ataaggcgtt cacgccgcat ccggcagtcg
      121 tgcgcagatg cctgatgcga cgctaacgcg tcttatcaga cctacaaatt ctcacgccat
      181 ccgtaggccg gataaggcgt tcacgccgca tccggcagtc gtgctgggat gggcatacaa
      241 aatgcacgtt ctcggcagtc atcattattt gttgttgcgc agatccagcg ccacgtcaac
      301 gatcatatcc tcctggccgc caaccatccg gcgtttgccc agctcaacga gaatatccac
      361 cgcacttaag ccataacgcg ccgccgccgt ttcacagtga cgcaggaagc tcgagtaaac
      421 accagcgtat cccagcgcca gcgtttcgcg atcgactcgt accggtcgat cctgcaacgg
      481 acgcacca
//
LOCUS       DACAOP010000293          475 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.306, whole genome shotgun sequence.
ACCESSION   DACAOP010000293 DACAOP010000000
VERSION     DACAOP010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..475
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.306"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>475
                     /locus_tag="IT892_004689"
     CDS             <1..>475
                     /locus_tag="IT892_004689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HAP3137782.1"
                     /translation="TVNGDPAEQWQYDEHGWLTTLSHTSEGHRVSVHYGYDDKGRLTG
                     ERQTVENPETGELLWHHETGHAYNEQGLANRVTPDSLPPVEWLTYGSGYLAGMKLGGT
                     PLLEFTRDRLHRETVRSFGSMAGSNAAYKLTSTYTPAGQLQSQHLNSLVYDRDYGW"
BASE COUNT          108 a          142 c          159 g           66 t
ORIGIN      
        1 acggtgaacg gcgacccggc agagcagtgg cagtatgatg agcacgggtg gttaaccacc
       61 ctcagccata ccagtgaagg ccaccgcgtg tcggtccact acggctatga cgataaaggc
      121 cgcctgaccg gcgaacgcca gacggtggag aacccggaga cgggggaact gctgtggcac
      181 catgagaccg gacatgcgta caacgaacag gggctggcaa accgcgtcac gccggacagt
      241 ctgccgccgg tggagtggct gacctacggc agcggctatc ttgcgggcat gaagctgggc
      301 gggacgccgc tgctggagtt cacgcgcgac cgcctgcacc gtgagacggt gcgcagcttc
      361 ggcagcatgg caggcagtaa tgccgcatat aaactgacca gcacatacac ccccgcaggc
      421 cagttacaga gccagcacct gaacagcctg gtgtatgacc gtgactacgg gtgga
//
LOCUS       DACAOP010000294          474 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.307, whole genome shotgun sequence.
ACCESSION   DACAOP010000294 DACAOP010000000
VERSION     DACAOP010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.307"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            136..432
                     /locus_tag="IT892_004690"
                     /pseudo
     CDS             136..432
                     /locus_tag="IT892_004690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708738.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4102 domain-containing protein"
BASE COUNT          127 a          123 c          107 g          117 t
ORIGIN      
        1 gtcctgccgc caaatcaatt ctaccgaact caaccagact ccccccacat caaccccatt
       61 gtgtgggtat aattgcgggt ataccccagt tcgacagaat ttgtaccctc tttaacgcat
      121 tcagaaggct gaactatggc actgactgac gcaaaaatcc gggctgcaaa gcacactgac
      181 aaggcttata aactcactga cggggctggc atgttcctgc tggtacatcc taatggttcc
      241 cgttactggc gtctccgtta tcgcattctg ggtaaggaga aaactctggc acttggtgta
      301 tacccggagg tttctctctc cgaagctcgt acaaaacggg atgaggcccg aaaactgatt
      361 tcggagggga ttgacccttg cgaacagaaa agagctaaaa aagtagtccc tgatttacaa
      421 ctctcttttg aaggcactgt tgcaaatagt cggtggtgat aaacttatca tccc
//
LOCUS       DACAOP010000295          473 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.308, whole genome shotgun sequence.
ACCESSION   DACAOP010000295 DACAOP010000000
VERSION     DACAOP010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.308"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..>473)
                     /locus_tag="IT892_004691"
     CDS             complement(<1..>473)
                     /locus_tag="IT892_004691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HAP3137783.1"
                     /translation="TVLVIKRVFRLTLRAAQGFIDSIFSLMNVPLRCPDYSCVSRRAK
                     SVNISFKTPTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRKLHLAVDSKTHE
                     IICADLSLNNVTDSEAFPGLIRQTHRKIRSAAADGAYDTRLCHDELRRKKISALIP"
BASE COUNT          104 a          126 c          128 g          115 t
ORIGIN      
        1 gggataagcg cgctgatttt cttacgccgc agttcatcgt gacagagccg ggtatcgtaa
       61 gctccatcgg cggcggctga cctgattttc cggtgggttt gccggattaa cccggggaag
      121 gcctctgagt ccgtaacgtt gttcagcgac aggtcagcgc agatgatttc atgtgtttta
      181 ctgtcaactg ccagatgcag cttacgccat atacgacggc gttcctggcc atgctttttg
      241 actttccact cgccttcacc gaagaccttc agcccggtgg aatcaattac caggtgtgcg
      301 atttcacccc gggtgggcgt tttgaaactg atattaaccg actttgcccg cctgctgaca
      361 cagctgtaat ccgggcagcg tagcggaacg ttcatcagag aaaaaatgga atcaataaag
      421 ccctgcgcag cgcgcagggt cagcctgaat acgcgtttaa tgaccagcac agt
//
LOCUS       DACAOP010000296          473 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.309, whole genome shotgun sequence.
ACCESSION   DACAOP010000296 DACAOP010000000
VERSION     DACAOP010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.309"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..>473)
                     /locus_tag="IT892_004692"
     CDS             complement(<1..>473)
                     /locus_tag="IT892_004692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HAP3137784.1"
                     /translation="TVLVIKRVFRLTLRAAQGFIDSIFSLMNVPLRCPDYSCVSRRAK
                     SVNVSFKTPTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRIWRKLHLAVDSKTHE
                     IICADLSLNNVTDSEAFPGLIRQTHRKIRSAAADGAYDTRLCHDELRRKKISALIP"
BASE COUNT          105 a          125 c          131 g          112 t
ORIGIN      
        1 gggataagcg cgctgatttt cttacgtcgc agttcatcgt gacagagccg ggtatcgtaa
       61 gcgccatcgg cggcggctga cctgattttc cggtgggttt gccggattaa cccggggaag
      121 gcctctgagt ccgtaacgtt gttcagcgac aggtcagcgc agatgatttc atgtgtttta
      181 ctgtcaacgg cgagatgcag cttacgccag atacggcggc gttcctggcc atgctttttg
      241 actttccact cgccttcacc gaagaccttc agcccggtgg aatcaattac caggtgtgcg
      301 atttcacccc gggtgggcgt tttgaaactg acattaaccg actttgcccg cctgctgaca
      361 cagctgtaat ccgggcagcg tagcggaacg ttcatcagag aaaaaatgga atcaataaaa
      421 ccctgtgcag cccgcagggt caacctgaac acgcgtttaa tgaccagaac ggt
//
LOCUS       DACAOP010000297          461 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.310, whole genome shotgun sequence.
ACCESSION   DACAOP010000297 DACAOP010000000
VERSION     DACAOP010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.310"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..407
                     /locus_tag="IT892_004693"
     CDS             <1..407
                     /locus_tag="IT892_004693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000906719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137785.1"
                     /translation="QLQQKEKSLIFFKHLCSVDESVKFYIDHKKGFDFKTALELDRKH
                     GAYWRPILKKLDIKYDCEYIESKRCSCNAACVSYDGFGENLLSNTLKYIQKGSLKKYN
                     PHLTPVLSDKWYKLGKNFFSWSCGPYKKARVG"
BASE COUNT          158 a           64 c           91 g          148 t
ORIGIN      
        1 gtcaattgca acaaaaagaa aaatctctca ttttctttaa gcatctttgc tccgtagatg
       61 aatcagtaaa attttatatt gaccataaaa aaggttttga ttttaaaaca gcccttgaac
      121 tcgatcgaaa acatggtgca tattggcgtc cgatattaaa gaagcttgat ataaaatatg
      181 attgtgagta tatcgaatca aaacgttgta gctgcaacgc tgcttgtgta agttatgatg
      241 gttttggaga gaatttgctc agcaatacat tgaaatatat acaaaaggga agtttaaaaa
      301 aatataatcc tcacctaaca ccagtgcttt ctgataaatg gtataagtta ggtaagaatt
      361 tctttagttg gagttgtggt ccatataaaa aagcaagggt tggttaaatt atcacagccc
      421 cgataaagtg ggctgtgatg ttattatctg tggttcttga g
//
LOCUS       DACAOP010000298          460 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.311, whole genome shotgun sequence.
ACCESSION   DACAOP010000298 DACAOP010000000
VERSION     DACAOP010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.311"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>460
                     /gene="waaZ"
                     /locus_tag="IT892_004694"
     CDS             <1..>460
                     /gene="waaZ"
                     /locus_tag="IT892_004694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-D-manno-oct-2-ulosonate III transferase
                     WaaZ"
                     /protein_id="HAP3137786.1"
                     /translation="RRDDFYKFSQRSRYTIVNVDVYEHASEEDKRYILQNCLVLRSFY
                     RREKGGLIKKIKFNILSRIHKELLISVPFSKKGRLVGFCKDINLGYCSCHTVVFAAIQ
                     IAYSLKYARIICSGLDLTGSCSRFYDEDKNPMPSELTRDLFKILPFFRFMR"
BASE COUNT          123 a           84 c           94 g          159 t
ORIGIN      
        1 cggcgtgatg atttttataa atttagccag agaagtcgtt ataccatcgt aaatgttgac
       61 gtttatgaac atgcttctga agaagataag cggtacatcc ttcaaaactg cctggtacta
      121 cgttcatttt accgcagaga aaaaggtgga ttgatcaaga agatcaagtt taatattttg
      181 agccgaattc ataaagagct cctgatctct gtaccttttt ctaaaaaagg tcgtctggtt
      241 ggcttttgca aggatattaa cctcggttat tgttcatgcc ataccgttgt ttttgctgca
      301 atccaaatag cctattcgct gaagtatgct cgtattatct gttcaggcct tgatttaacg
      361 ggtagctgtt cgcgtttcta tgatgaagat aagaatccta tgccctcaga gttgactcgg
      421 gatttattca aaattttacc atttttccgt tttatgcgtg
//
LOCUS       DACAOP010000299          458 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.312, whole genome shotgun sequence.
ACCESSION   DACAOP010000299 DACAOP010000000
VERSION     DACAOP010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.312"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>458
                     /locus_tag="IT892_004695"
     CDS             <1..>458
                     /locus_tag="IT892_004695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137787.1"
                     /translation="YRTKTPAPVGSLGPGWKMPADIRLQLRDNTLILSDNGGRSLYFE
                     HLFPGEDGYSRSESLWLVRGGVAKLDEGHRLAALWQALPEELRLSPHRYLATNSPQGP
                     WWLLGWCERVPEADEVLPAPLPPYRVLTGLVDRFGRTQTFHREAAGEFSG"
BASE COUNT           83 a          135 c          161 g           79 t
ORIGIN      
        1 taccggacaa aaacgcccgc gccggtgggg agcctcggcc ccggctggaa aatgcctgcg
       61 gatatccgct tacagctgcg cgataacaca ctgatactca gtgataacgg cggcagaagc
      121 ctgtattttg agcacctgtt tcccggtgag gacggttaca gccgcagcga gtcactgtgg
      181 ctggtgcgcg gcggcgtggc gaaactggat gaaggtcacc ggctggccgc actctggcag
      241 gcgctgccgg aagaactccg cttaagtccg catcgttatc tggcgacaaa cagtccgcag
      301 gggccgtggt ggctgctcgg ttggtgtgag cgggtgccgg aagcggatga ggtgctgcct
      361 gcgccgctgc cgccgtaccg ggtactgacc gggctggtgg accgcttcgg gcgcacacag
      421 acgttccacc gcgaagccgc cggtgaattc agcggcga
//
LOCUS       DACAOP010000300          445 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.313, whole genome shotgun sequence.
ACCESSION   DACAOP010000300 DACAOP010000000
VERSION     DACAOP010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.313"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..203)
                     /locus_tag="IT892_004696"
     CDS             complement(<1..203)
                     /locus_tag="IT892_004696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312164.1"
                     /note="with AcrD and TolC forms a transport system
                     involved in resistance to a number of compounds including
                     lipophilic antibiotics; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux transporter periplasmic adaptor subunit"
                     /protein_id="HAP3137788.1"
                     /translation="MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIV
                     KTAPLEVKTELPGRTNAYRIAEVR"
BASE COUNT          148 a           89 c           90 g          118 t
ORIGIN      
        1 cgaacttcgg ctatacgata agcattggtg cggcctggta attcagtctt aacttctaac
       61 ggggccgttt ttacaatatg aacggtaacc tgcggttcac cgacgtgagc tttctcttct
      121 cccttatcgt tacaaccggc gattaaagcc gcggagatca gaataaagga gggcaggagg
      181 aaaaacctgg catgtttcgt cattactatt cctcaaaaaa ccaaaagcgc gttatttacc
      241 caaaaaggca acgcgttaac tcgcagaaag aaaaatacag ttcgctatcc tacaaattat
      301 cattcgtcga tgtaaggaat agttatgaat acaggcatct caaggcacat aaacacaaaa
      361 aaagattaat attctactgt tttattttga cgcgggttga aagaggcaga attaaaacct
      421 cgtaaattga aatatatatt gatgt
//
LOCUS       DACAOP010000301          427 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.314, whole genome shotgun sequence.
ACCESSION   DACAOP010000301 DACAOP010000000
VERSION     DACAOP010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.314"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            88..279
                     /locus_tag="IT892_004697"
     CDS             88..279
                     /locus_tag="IT892_004697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2633 family protein"
                     /protein_id="HAP3137789.1"
                     /translation="MSQATSMRKRHRFNSRMTRIVLLISFIFFFGRFIYSSVGAWQHH
                     QSKKEAQQSTLSVESPVQR"
BASE COUNT          105 a          109 c           84 g          129 t
ORIGIN      
        1 tacataacga agaattgacc attttgtcct gttgtgcctt aatgtaagta ccgtccacag
       61 cgtgggacat acttcaagga accttttgtg agtcaggcaa ccagtatgcg aaaacgacac
      121 cgatttaaca gtcgcatgac ccgtatcgta ctgctcatca gctttatctt cttctttggc
      181 cgttttatct actcgtccgt cggtgcatgg cagcaccatc agagcaaaaa agaagctcag
      241 caatccacac tctccgtcga atcaccggta caacgttagc ggttaccttc tccactttca
      301 cagaacataa cggcacctcg ctgtcggatg cttttgctct ttgggattat caaagcggca
      361 gatattcttt catcttaaat tttacgtctt tgtcctgact gatgtttatc ctgtttggct
      421 gcgaaat
//
LOCUS       DACAOP010000302          417 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.315, whole genome shotgun sequence.
ACCESSION   DACAOP010000302 DACAOP010000000
VERSION     DACAOP010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.315"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(107..>417)
                     /locus_tag="IT892_004698"
     CDS             complement(107..>417)
                     /locus_tag="IT892_004698"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137790.1"
                     /translation="IMNTEKYQTIEEKILAIYSGKAEKLAQRKSAVLKELITANSAKA
                     IEELTRERMVIDKRLFVCKNILNSIRNASSKKNENFSNYVVVLSTEAARLNMLTPYTV
                     "
BASE COUNT          131 a           71 c           68 g          147 t
ORIGIN      
        1 taaatataca actaaatata ccttcaaata tataaatttc ggacatatgg tttaccagaa
       61 aacaaaaaag ccccaaaaaa ggggcttagt gagagagatg tttccgttaa acggtgtacg
      121 gtgtcagcat atttaatctt gctgcttcgg tagaaagcac aacaacataa ttagaaaagt
      181 tttcattttt ctttgatgaa gcattacgaa tgctgttgag tatgttttta cagacaaaaa
      241 gccttttgtc gataaccatt ctttctcttg taagttcttc aatagctttc gcactgttag
      301 ctgtaatcag ttctttaaga acagcacttt ttctttgagc cagtttttca gcttttccag
      361 aatagatagc caggatcttt tcttcaatgg tttgatattt ttcagtattc ataatac
//
LOCUS       DACAOP010000303          408 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.316, whole genome shotgun sequence.
ACCESSION   DACAOP010000303 DACAOP010000000
VERSION     DACAOP010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.316"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
BASE COUNT          122 a           92 c           87 g          107 t
ORIGIN      
        1 gtaagttgga gtcattaccc atttgacata tgggttacct gtccactcac ctcacctgac
       61 gatataaaaa atttcagaaa cagtttcaat aaggccaagg cgcagcgcaa gtacaaaaaa
      121 atgcaggaag ataaagtcaa tgtacagttt tttcttgacg cagaaaccag ggcgcagctc
      181 aaagaattat ccagggtcag aagactcagt accggagaaa tgctgcatga cctgattgtt
      241 gaagagtata aaaggtaccg acattccaga taatttcaga catatattat ctccgtgagt
      301 cccccgcctc ctttccggtg tgcggggttt ttgtcttttt tcaccgggaa tacatgtatg
      361 aatccgtctg atgccattga ggcaattgaa aaaccgctct cctccctg
//
LOCUS       DACAOP010000304          401 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.317, whole genome shotgun sequence.
ACCESSION   DACAOP010000304 DACAOP010000000
VERSION     DACAOP010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.317"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..140
                     /locus_tag="IT892_004699"
     CDS             <1..140
                     /locus_tag="IT892_004699"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="V-type ATPase 116kDa subunit family protein"
                     /protein_id="HAP3137791.1"
                     /translation="NQQTSSERELEMSTEIARLKRQLAERDEELAILQKAATYFAKRL
                     K"
     gene            137..>401
                     /locus_tag="IT892_004700"
     CDS             137..>401
                     /locus_tag="IT892_004700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP3137792.1"
                     /translation="MKYVFIEKHQAEFSIKAMCRVLRVARSGWYTWCQRRTRISTRQQ
                     FRQHCDSVVLAAFTRSKQRYGAPRLTDELRAQGYPFNVKTVAAS"
BASE COUNT          101 a          110 c          112 g           78 t
ORIGIN      
        1 aaaatcagca gacgtcttct gaacgtgaac tggagatgtc taccgagatt gcacgtctca
       61 aacgccagct ggcagaacgg gatgaagagc tggctatcct ccaaaaggcc gcgacatact
      121 tcgcgaagcg cctgaaatga agtatgtctt tattgaaaaa catcaggctg agttcagcat
      181 caaagcaatg tgccgcgtgc tccgggtggc ccgcagcggc tggtatacgt ggtgtcagcg
      241 gcggacaagg ataagcacgc gtcagcagtt ccgccaacac tgcgacagcg ttgtcctcgc
      301 ggcttttacc cggtcaaaac agcgttacgg tgccccacgc ctgacggatg aactgcgtgc
      361 tcagggttac ccctttaacg taaaaaccgt ggcggcaagc c
//
LOCUS       DACAOP010000305          391 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.318, whole genome shotgun sequence.
ACCESSION   DACAOP010000305 DACAOP010000000
VERSION     DACAOP010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.318"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>391
                     /locus_tag="IT892_004701"
     CDS             <1..>391
                     /locus_tag="IT892_004701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP3137793.1"
                     /translation="YVAFIIDVFAGYIVGWRVSSSMETTFVLDALEQALWARRPSGTV
                     HHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAEVIHRKSWKN
                     RAEVELATLTWVDWYNNRRLLERLGHTP"
BASE COUNT           98 a           91 c          118 g           84 t
ORIGIN      
        1 tctatgtggc gttcatcatt gatgtgtttg ccggatacat cgtggggtgg cgggtctcat
       61 cgtccatgga aacgacattc gtgctggatg cactggagca ggcgttatgg gcccgtcgac
      121 cgtccggcac ggtccatcac agtgataaag gttctcagta tgtatcgctg gcctacacac
      181 agcggcttaa ggaagccgga ttactggcat caacaggaag tacaggcgac tcgtatgaca
      241 acgcgatggc ggagagcatc aatggtcttt acaaagcgga ggtaatacac cgtaagagct
      301 ggaaaaaccg tgcagaagtg gaactggcca cactcacgtg ggtggactgg tataacaatc
      361 gacgattgct ggaaaggctg ggccatactc c
//
LOCUS       DACAOP010000306          373 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.319, whole genome shotgun sequence.
ACCESSION   DACAOP010000306 DACAOP010000000
VERSION     DACAOP010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.319"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>373
                     /locus_tag="IT892_004702"
     CDS             <1..>373
                     /locus_tag="IT892_004702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="HAP3137794.1"
                     /translation="NPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVD
                     FYLSSRRNSKAAYRFLGKILN"
BASE COUNT           82 a          101 c          102 g           88 t
ORIGIN      
        1 tgaacccatt caaaggccgg cattttcagc gtgacatcat tctgtgggcc gtacgctggt
       61 actgcaaata cggcatcagt taccgtgagc tgcaggagat gctggctgaa cgcggagtga
      121 atgtcgatca ctccacgatt taccgctggg ttcagcgtta tgcgcctgaa atggaaaaac
      181 ggctgcgctg gtactggcgt aacccttccg atctttgccc gtggcacatg gatgaaacct
      241 acgtgaaggt caatggccgc tgggcgtatc tgtaccgggc cgtcgacagc cggggccgca
      301 ctgtcgattt ttatctctcc tcccgtcgta acagcaaagc tgcataccgg tttctgggta
      361 aaatcctcaa caa
//
LOCUS       DACAOP010000307          371 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.320, whole genome shotgun sequence.
ACCESSION   DACAOP010000307 DACAOP010000000
VERSION     DACAOP010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..371
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.320"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            24..100
                     /locus_tag="IT892_004703"
     tRNA            24..100
                     /locus_tag="IT892_004703"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:58..60,aa:Ile,seq:gat)
     gene            143..218
                     /locus_tag="IT892_004704"
     tRNA            143..218
                     /locus_tag="IT892_004704"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:176..178,aa:Ala,seq:tgc)
BASE COUNT          105 a           79 c           90 g           97 t
ORIGIN      
        1 aaaatgagca gtaaaacctc tacaggcttg tagctcaggt ggttagagcg cacccctgat
       61 aagggtgagg tcggtggttc aagtccactc aggcctacca aatttgcacg gcaaatttga
      121 agaggtttta actacatgtt atggggctat agctcagctg ggagagcgcc tgctttgcac
      181 gcaggaggtc tgcggttcga tcccgcatag ctccaccatc tctgtagtga ttaaataaaa
      241 aatacttcag agtgtacctg caaaggttca ctgcgaagtt ttgctcttta aaaatctgga
      301 tcaagctgaa aattgaaaca ctgaacaacg aaagttgttc gtgagtctct caaattttcg
      361 cgactctgaa g
//
LOCUS       DACAOP010000308          367 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.321, whole genome shotgun sequence.
ACCESSION   DACAOP010000308 DACAOP010000000
VERSION     DACAOP010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.321"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>367
                     /locus_tag="IT892_004705"
     CDS             <1..>367
                     /locus_tag="IT892_004705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HAP3137795.1"
                     /translation="DFLKQYGDFENGIPVHDTIARVVSCISPSKFHECFINWMRDCHT
                     SDDKDVIAIDGKTLRHSYDKSRRKGAIHVISAFSTMHSLVIGQIRTDEKSNEITAIPE
                     LLNMLDIKGKIITTDAMGCQ"
BASE COUNT          113 a           74 c           78 g          102 t
ORIGIN      
        1 cgatttttta aaacaatatg gtgattttga aaatggtatt cctgttcacg ataccatcgc
       61 cagagttgta tcctgtatca gtccttcaaa atttcacgag tgctttatta actggatgcg
      121 agattgccat acttcagatg ataaagacgt catcgcaatt gatggaaaaa cactccggca
      181 ttcttatgac aagagtcgcc gcaagggagc gattcatgtc attagtgcgt tctcaacaat
      241 gcacagtctg gtcatcggac agatcaggac ggatgagaaa tccaatgaga ttacagctat
      301 ccctgaactt cttaacatgc tggatattaa aggaaaaatc atcacaactg atgcgatggg
      361 ttgccag
//
LOCUS       DACAOP010000309          344 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.322, whole genome shotgun sequence.
ACCESSION   DACAOP010000309 DACAOP010000000
VERSION     DACAOP010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..344
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.322"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            38..>344
                     /locus_tag="IT892_004706"
     CDS             38..>344
                     /locus_tag="IT892_004706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HAP3137796.1"
                     /translation="MSGILLLTIFAVISGAESWEDIEDFGETHLDFLKQYGDFENGIP
                     VHDTIARVVSCISPAKFHECFINWMRDCHSSNDKDVIAIDGKTLRHSYDKSRRRGAIH
                     "
BASE COUNT           99 a           63 c           79 g          103 t
ORIGIN      
        1 tcccgattac agataagcct ggaaagtaga gcataaattg tcaggcatcc tactattgac
       61 tatttttgcc gttatttctg gtgcagaaag ttgggaagat atagaggatt tcggggaaac
      121 acatctcgat ttcttgaagc aatatggtga ttttgaaaat ggtattcctg ttcacgatac
      181 tattgccaga gttgtatcct gtatcagtcc tgcaaaattt cacgagtgct ttattaactg
      241 gatgcgtgat tgccattcat caaatgataa agacgtcatt gcaattgatg gaaaaacgct
      301 ccggcactct tatgacaaga gtcgccgcag gggagcgatt catg
//
LOCUS       DACAOP010000310          298 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.323, whole genome shotgun sequence.
ACCESSION   DACAOP010000310 DACAOP010000000
VERSION     DACAOP010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.323"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..292
                     /locus_tag="IT892_004707"
     CDS             <1..292
                     /locus_tag="IT892_004707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP3137797.1"
                     /translation="HTDRGGQYCSADYQAQLKRHNLRGSMSAKGCCYDNACVESFFHS
                     LKVECIHGEHFISREIMRATVFNYIECDYNRWRRHSWCGGLSPEQFENKNLA"
BASE COUNT           80 a           62 c           85 g           71 t
ORIGIN      
        1 tcacacggac cgtggaggcc agtactgttc agcagattat caggcgcaac tgaagcggca
       61 taatctgcgt ggaagtatga gcgcaaaagg ttgctgctac gataatgcct gcgtggaaag
      121 cttctttcat tcgctgaaag tggaatgtat ccatggagaa cactttatca gccgggaaat
      181 aatgcgggca acggtgttta attatatcga atgtgattac aatcggtggc ggcggcacag
      241 ttggtgtggc ggcctcagtc cggaacaatt tgaaaacaag aacctcgctt aggcctgt
//
LOCUS       DACAOP010000311          295 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.324, whole genome shotgun sequence.
ACCESSION   DACAOP010000311 DACAOP010000000
VERSION     DACAOP010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.324"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>295
                     /locus_tag="IT892_004708"
     CDS             <1..>295
                     /locus_tag="IT892_004708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HAP3137798.1"
                     /translation="AGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAGEIHFDNQTTPD
                     AALSRAVAKGDSPVTFHKLTTSNLTGQGGTINMRVRLDGSNASDQLVINGGQAT"
BASE COUNT           73 a           75 c           87 g           60 t
ORIGIN      
        1 ctgccggggg aagtctgagt ggcagaacac agctcagtaa aggcgccagc atggtactga
       61 atggtgatgt ggtcagtacc ggcgatattg ttaacgcagg agagattcac tttgataatc
      121 agacgacacc ggatgccgcg ctgagccgtg ctgttgcaaa aggcgactcc ccggtaacgt
      181 tccataaact gaccaccagt aacctcaccg gtcagggggg caccatcaat atgcgtgttc
      241 gccttgatgg cagcaatgcc tctgaccagc tggtgattaa tggtggccag gcaac
//
LOCUS       DACAOP010000312          294 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.325, whole genome shotgun sequence.
ACCESSION   DACAOP010000312 DACAOP010000000
VERSION     DACAOP010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.325"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            19..103
                     /locus_tag="IT892_004709"
     tRNA            19..103
                     /locus_tag="IT892_004709"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:53..55,aa:Tyr,seq:gta)
     gene            147..278
                     /locus_tag="IT892_004710"
     ncRNA           147..278
                     /ncRNA_class="other"
                     /locus_tag="IT892_004710"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
BASE COUNT           80 a           79 c           76 g           59 t
ORIGIN      
        1 aaaatttgaa ttacccctgg tggggttccc gagcggccaa agggagcaga ctgtaaatct
       61 gccgtcatcg acttcgaagg ttcgaatcct tcccccacca ccataattca ccacagcgat
      121 gtggtaactt cggtgagatt gtgaaagttt gcactcatcg gggaagggtg agaaccttcg
      181 actaaggttc gattcgagcg aaagcgagag aacgttgcca caggcaacgg cccgaagggt
      241 gaggagcgaa gcgacgaata atccttcccc caccaccatc tcaagcatta cctc
//
LOCUS       DACAOP010000313          293 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.326, whole genome shotgun sequence.
ACCESSION   DACAOP010000313 DACAOP010000000
VERSION     DACAOP010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.326"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..258
                     /locus_tag="IT892_004711"
     CDS             <1..258
                     /locus_tag="IT892_004711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HAP3137799.1"
                     /translation="WPGEYADRNRAVANQRMTGSNARWKWTTDYNRRSIAETAMYRVK
                     QLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA"
BASE COUNT           80 a           68 c           93 g           52 t
ORIGIN      
        1 tggcccggtg aatatgcaga ccgtaaccgt gcagtggcta atcagcgaat gaccgggagt
       61 aatgcgcggt ggaaatggac aacagattac aaccgtcgct cgatagcgga aacggcgatg
      121 taccgggtaa aacagctgtt cgggggttca ctgacgctgc gtgactacga tggtcaggtt
      181 gcggaggcta tggccctggt acgagcgctg aacaaaatga cgaaagcagg tatgcctgaa
      241 agcgtgcgta ttgcctgaaa acacaacccg ctacggggga gacttacccg aaa
//
LOCUS       DACAOP010000314          273 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.327, whole genome shotgun sequence.
ACCESSION   DACAOP010000314 DACAOP010000000
VERSION     DACAOP010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.327"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            45..>273
                     /locus_tag="IT892_004712"
     CDS             45..>273
                     /locus_tag="IT892_004712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP3137800.1"
                     /translation="MSRKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQW
                     VTAARKGLGTPGSRTVAELESEILQLRKALNE"
BASE COUNT           82 a           63 c           66 g           62 t
ORIGIN      
        1 ggacactcct tcctgaaata gaatggcatc agaaggagct aataatgagc agaaaaaccc
       61 aacgttactc taaagagttc aaagccgaag ctgtcagaac ggttcttgaa aatcaacttt
      121 cgatcagtga aggcgcttcc cgattatctc ttcctgaagg cactttagga caatgggtta
      181 ccgccgccag aaaagggctc ggtactcctg gttcccgcac ggtggctgaa ctggaatctg
      241 aaattctgca actgcgtaag gcgttaaatg aag
//
LOCUS       DACAOP010000315          272 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.328, whole genome shotgun sequence.
ACCESSION   DACAOP010000315 DACAOP010000000
VERSION     DACAOP010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.328"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..158
                     /locus_tag="IT892_004713"
     CDS             <1..158
                     /locus_tag="IT892_004713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HAP3137801.1"
                     /translation="MDACIASADNKTIARQMNKTVEILVGPHPEQYVWVLKLLKTRKS
                     NEADPYP"
BASE COUNT           92 a           55 c           62 g           63 t
ORIGIN      
        1 caatggatgc ttgcattgcc agcgcggaca ataaaacgat tgcccgacaa atgaacaaaa
       61 cagtggaaat tttggtgggg ccacatccgg aacagtatgt ctgggtttta aaattgttaa
      121 aaacacgcaa atcaaacgaa gcggacccgt acccttgaaa ttataaagta caagtatttc
      181 cactagttgt ttgtaagcgt acagcctgaa ccgtctggtc agaatctgac gaattagaca
      241 aagtggtgtc caccaaataa gtagtgggaa cc
//
LOCUS       DACAOP010000316          270 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.329, whole genome shotgun sequence.
ACCESSION   DACAOP010000316 DACAOP010000000
VERSION     DACAOP010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.329"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
BASE COUNT          112 a           54 c           24 g           80 t
ORIGIN      
        1 cttgaaagga taaaaattca cattatcacc ataaaatcac aacgacacca aaacacatct
       61 cacaacaaca cccttgcaat aaacctgttt ttaacaaaaa atcaaagact gaaaagaatt
      121 ttgattcaga aaaccacatg agacatgctt aatatttttc agtttatcta aaggacgcgt
      181 tcatctttat tacaaaaata taagtacact gtacttatta aacatccaaa aatcacacca
      241 gttaatattt cttgtattac tgtaatttct
//
LOCUS       DACAOP010000317          264 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.330, whole genome shotgun sequence.
ACCESSION   DACAOP010000317 DACAOP010000000
VERSION     DACAOP010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..264
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.330"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>264
                     /locus_tag="IT892_004714"
     rRNA            <1..>264
                     /locus_tag="IT892_004714"
                     /product="16S ribosomal RNA"
BASE COUNT           66 a           60 c           81 g           57 t
ORIGIN      
        1 gagagcaagc ggacctcata aagtgcgtcg tagtccggat tggagtctgc aactcgactc
       61 catgaagtcg gaatcgctag taatcgtgga tcagaatgcc acggtgaata cgttcccggg
      121 ccttgtacac accgcccgtc acaccatggg agtgggttgc aaaagaagta ggtagcttaa
      181 ccttcgggag ggcgcttacc actttgtgat tcatgactgg ggtgaagtcg taacaaggta
      241 accgtagggg aacctgcggt tgga
//
LOCUS       DACAOP010000318          263 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.331, whole genome shotgun sequence.
ACCESSION   DACAOP010000318 DACAOP010000000
VERSION     DACAOP010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.331"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>263
                     /locus_tag="IT892_004715"
     CDS             <1..>263
                     /locus_tag="IT892_004715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP3137802.1"
                     /translation="VVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLE
                     LVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILEL"
BASE COUNT           58 a           64 c           81 g           60 t
ORIGIN      
        1 gtagttgctg cgactgacgg cccgatgccg cagactcgtg agcacatcct gctgggtcgt
       61 caggtaggcg ttccgtacat catcgtgttc ctgaacaaat gcgacatggt tgatgacgaa
      121 gagctgctgg aactggttga aatggaagtt cgtgaacttc tgtctcagta cgacttcccg
      181 ggcgacgaca ctccgatcgt tcgtggttct gctctgaaag cgctggaagg cgacgcagag
      241 tgggaagcga aaatcctgga act
//
LOCUS       DACAOP010000319          252 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.332, whole genome shotgun sequence.
ACCESSION   DACAOP010000319 DACAOP010000000
VERSION     DACAOP010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..252
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.332"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>252
                     /locus_tag="IT892_004716"
     rRNA            <1..>252
                     /locus_tag="IT892_004716"
                     /product="23S ribosomal RNA"
BASE COUNT           76 a           56 c           71 g           49 t
ORIGIN      
        1 gttaagcgac taagcgtaca cggtggatgc cctggcagtc agaggcgatg aaggacgtgc
       61 taatctgcga taagcgtcgg taaggtgata tgaaccgtta taaccggcga tttccgaatg
      121 gggaaaccca gtgtgtttcg acacactatc attaactgaa tccataggtt aatgaggcga
      181 accgggggaa ctgaaacatc taagtacccc gaggaaaaga aatcaaccga gattccccca
      241 gtagcggcga gc
//
LOCUS       DACAOP010000320          250 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.333, whole genome shotgun sequence.
ACCESSION   DACAOP010000320 DACAOP010000000
VERSION     DACAOP010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..250
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.333"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
BASE COUNT           61 a           57 c           69 g           63 t
ORIGIN      
        1 tcggcttacc tcctttcgcc ctgaatgcag tctatcgctg acttgcggat aaaatagttt
       61 cacatgtgat tattgcgtga cgtctcgcaa agaatatttg ctggcaggat cgcagactgc
      121 aaagcctgcg gattgacaat cggaccgtga aggcatactt tcaggagtga gggtagagcg
      181 gggtttcccc cgccctggta gtcttagtaa gctgggtagc taacgactaa gagcaccacg
      241 atgatgagta
//
LOCUS       DACAOP010000321          244 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.334, whole genome shotgun sequence.
ACCESSION   DACAOP010000321 DACAOP010000000
VERSION     DACAOP010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..244
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.334"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(20..229)
                     /gene="mokC"
                     /locus_tag="IT892_004717"
     CDS             complement(20..229)
                     /gene="mokC"
                     /locus_tag="IT892_004717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin MokC"
                     /protein_id="HAP3137803.1"
                     /translation="MLNTCRVPLTDRKVKEKRAMKQHKAMIVALIVICITAVVAALVT
                     RKDLCEVHIRTGQTEVAVFTAYESE"
BASE COUNT           50 a           72 c           59 g           63 t
ORIGIN      
        1 tcactccccg ccgttgctct tactcggatt cgtaagcagt gaaaacagca acctccgtct
       61 ggccagttcg gatgtgaacc tcacagaggt cttttctcgt taccagcgcc gccactacgg
      121 cggtgataca gatgacgatc agggcgacaa tcatcgcctt atgctgcttc attgctctct
      181 tctccttgac cttacggtca gtaagaggca ctctacatgt gttcagcata tagggggcct
      241 cggg
//
LOCUS       DACAOP010000322          226 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.335, whole genome shotgun sequence.
ACCESSION   DACAOP010000322 DACAOP010000000
VERSION     DACAOP010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..226
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.335"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(36..110)
                     /locus_tag="IT892_004718"
     tRNA            complement(36..110)
                     /locus_tag="IT892_004718"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(76..78),aa:Gln,seq:ttg)
     gene            complement(134..218)
                     /locus_tag="IT892_004719"
     tRNA            complement(134..218)
                     /locus_tag="IT892_004719"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(182..184),aa:Leu,seq:tag)
BASE COUNT           55 a           64 c           58 g           49 t
ORIGIN      
        1 accaactgag ctacgtagcc agattgtttc ttcgatggct ggggtacctg gattcgaacc
       61 agggaatgcc ggtatcaaaa accggtgcct taccgcttgg cgatacccca tccgtacaac
      121 gctttctggt gaatggtgcg ggaggcgaga cttgaactcg cacaccttgc ggcgccagaa
      181 cctaaatctg gtgcgtctac caatttcgcc actcccgcaa aaaaag
//
LOCUS       DACAOP010000323          220 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.336, whole genome shotgun sequence.
ACCESSION   DACAOP010000323 DACAOP010000000
VERSION     DACAOP010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..220
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.336"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>220
                     /locus_tag="IT892_004720"
     CDS             <1..>220
                     /locus_tag="IT892_004720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP3137804.1"
                     /translation="MLNKGLESLAEGEKPLLHSDQGWHYRIKSYQSDLADKGLVQSMS
                     RKGNCLDNAVMENFFGHLKEEIYYRRDYR"
BASE COUNT           71 a           40 c           61 g           48 t
ORIGIN      
        1 atgttaaata aggggctgga aagccttgca gaaggagaaa aaccgctgct ccacagtgat
       61 caagggtggc attaccggat aaaaagttat cagtctgacc tggcagacaa agggttagtg
      121 cagagcatgt cgcgcaaggg caactgtctt gataatgcgg taatggagaa tttctttggt
      181 cacctgaaag aagaaattta ctatcgccgg gactacagaa
//
LOCUS       DACAOP010000324          217 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.337, whole genome shotgun sequence.
ACCESSION   DACAOP010000324 DACAOP010000000
VERSION     DACAOP010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..217
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.337"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>217
                     /locus_tag="IT892_004721"
     rRNA            <1..>217
                     /locus_tag="IT892_004721"
                     /product="23S ribosomal RNA"
BASE COUNT           57 a           55 c           58 g           47 t
ORIGIN      
        1 ccggtaaacg gcggccgtaa ctataacggt cctaaggtag cgaaattcct tgtcgggtaa
       61 gttccgacct gcacgaatgg cgtaatgatg gccaggctgt ctccacccga gactcagtga
      121 aattgaactc gctgtgaaga tgcagtgtac ccgcggcaag acggaaagac cccgtgaacc
      181 tttactatag cttgacactg aacattgagc cttgatg
//
LOCUS       DACAOP010000325          216 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.338, whole genome shotgun sequence.
ACCESSION   DACAOP010000325 DACAOP010000000
VERSION     DACAOP010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..216
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.338"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>216
                     /locus_tag="IT892_004722"
     CDS             <1..>216
                     /locus_tag="IT892_004722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAP3137805.1"
                     /translation="LNSLTLACHALLDCKTLTLTELGRNLPTKARTKHNIKRIDRLLG
                     NRHLHKERLAVYRWHASFICSGNTMPIV"
BASE COUNT           63 a           60 c           40 g           53 t
ORIGIN      
        1 actcaacagc ttaacgttgg cttgccacgc attacttgac tgtaaaactc tcactcttac
       61 cgaacttggc cgtaacctgc caaccaaagc gagaacaaaa cataacatca aacgaatcga
      121 ccgattgtta ggtaatcgtc acctccacaa agagcgactc gctgtatacc gttggcatgc
      181 tagctttatc tgttcgggca atacgatgcc cattgt
//
LOCUS       DACAOP010000326          211 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.339, whole genome shotgun sequence.
ACCESSION   DACAOP010000326 DACAOP010000000
VERSION     DACAOP010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..211
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.339"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>211
                     /locus_tag="IT892_004723"
     CDS             <1..>211
                     /locus_tag="IT892_004723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HAP3137806.1"
                     /translation="RLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYTQRIERH
                     NLNLRQHLARLGRKSLSFSKSVELH"
BASE COUNT           49 a           50 c           67 g           45 t
ORIGIN      
        1 ggcgtcttat gagcctgctg tcaccctttg acgtggtgat atggatgacg gatggctggc
       61 cgctgtatga atcccgcctg aagggaaagc tgcacgtaat cagcaagcga tatacgcagc
      121 gaattgagcg gcataacctg aatctgaggc agcacctggc acggctggga cggaagtcgc
      181 tgtcgttctc aaaatcggtg gagctgcatg a
//
LOCUS       DACAOP010000327          208 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.340, whole genome shotgun sequence.
ACCESSION   DACAOP010000327 DACAOP010000000
VERSION     DACAOP010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..208
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.340"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..177)
                     /locus_tag="IT892_004724"
     CDS             complement(<1..177)
                     /locus_tag="IT892_004724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAP3137807.1"
                     /translation="MNYSHDNWSAILAHIGKPEELDTSARNAGALTRRREIRDAATLL
                     RLGLAYGPGGMSLRE"
BASE COUNT           51 a           57 c           54 g           46 t
ORIGIN      
        1 ttcacgtaat gacatccccc cggggccgta agccagcccc agacgtagca gagttgcagc
       61 atcacgaatt tcgcggcggc gggttagagc cccggcatta cgtgccgaag tatccagttc
      121 ttcgggctta ccaatatggg ccagaattgc tgaccagtta tcgtgagagt aattcatcgg
      181 cacgttaaat catatcaggc gtaatacc
//
LOCUS       DACAOP010000328          201 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.341, whole genome shotgun sequence.
ACCESSION   DACAOP010000328 DACAOP010000000
VERSION     DACAOP010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..201
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.341"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..>201
                     /locus_tag="IT892_004725"
     CDS             <1..>201
                     /locus_tag="IT892_004725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HAP3137808.1"
                     /translation="FTTLKKLRPQSVNSRIQPGSDVIVCAEMDEQWGYVGAKSRQRWL
                     FYAYDRIRRTVVAHVFGERTLAT"
BASE COUNT           49 a           47 c           60 g           45 t
ORIGIN      
        1 ttttacgaca cttaaaaaac tcaggccgca gtcggtaaac tcacgcatac aaccgggcag
       61 tgacgtcatt gtttgcgcgg aaatggacga acagtggggt tacgtcggcg ctaaatcacg
      121 ccagcgctgg ttgttttacg cgtatgacag gatacggagg acggttgtgg cgcatgtatt
      181 cggtgaacgc acgttggcca c
//
LOCUS       DACAOP010000329          200 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.342, whole genome shotgun sequence.
ACCESSION   DACAOP010000329 DACAOP010000000
VERSION     DACAOP010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..200
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.342"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
BASE COUNT           81 a           26 c           39 g           54 t
ORIGIN      
        1 aaacgcagcc taaataatat ctggaataaa gaagatggca ctgaatttat taagagattg
       61 caaagacatt aagggtgaag aggaaaagaa agaaggctgc gttaaacaca gggaaagatc
      121 atcagaagtt cactttttgt actaaacaat tcgcattata tgtttaaaaa ttgagatatt
      181 ccttattacc taaagctgtt
//
LOCUS       DACAOP010000330          200 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.343, whole genome shotgun sequence.
ACCESSION   DACAOP010000330 DACAOP010000000
VERSION     DACAOP010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..200
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.343"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
BASE COUNT           56 a           47 c           53 g           44 t
ORIGIN      
        1 agccagtcct gcggtaagtg gtacatcagt attcagacag aaagtgaagt atcaactccg
       61 gttcaccctt cagcatcaat ggtcgggctg gatgctggcg tggctaaact cgccacgctg
      121 tcagatggca cagtctttga gcctgtaaac agttttcaga aaaaccagaa gaagctggcg
      181 agacttcagc gacagttaag
//
LOCUS       DACAOP010000331          200 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.denovo.344, whole genome shotgun sequence.
ACCESSION   DACAOP010000331 DACAOP010000000
VERSION     DACAOP010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..200
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.denovo.344"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
BASE COUNT           45 a           60 c           62 g           33 t
ORIGIN      
        1 tataacccgt caaaccagga cagttcatgc tggatccgtg tggcacaggc gtgggcaggc
       61 accggattcg gtaacctggc gataccgcgt gtgggtcagg aggtgattgt ggacttcctc
      121 aacggcgatc cggaccagcc gatcattatg gggcgcacct accaccagga aaaccgcaca
      181 cccggcagcc tgccgggaac
//
LOCUS       DACAOP010000332         6199 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.169, whole genome shotgun sequence.
ACCESSION   DACAOP010000332 DACAOP010000000
VERSION     DACAOP010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6199
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.169"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            1091..1495
                     /locus_tag="IT892_004728"
     CDS             1091..1495
                     /locus_tag="IT892_004728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication initiation protein"
                     /protein_id="HAP3137809.1"
                     /translation="MLHVAGEKRQHRRVSRICDTGDIPLPRSLTRYARSFGCGERYRL
                     TDGDGNFLEDTRKTLSKEEIRPRRSRFSIGSAPLTSIAKSDAQISGGETRQDYKDPRR
                     FPLVAPSCALLFLPFGLPVSFRCYGRGFSFHA"
     gene            2155..2970
                     /gene="sul2"
                     /locus_tag="IT892_004729"
     CDS             2155..2970
                     /gene="sul2"
                     /locus_tag="IT892_004729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /protein_id="HAP3137810.1"
                     /translation="MNKSLIIFGIVNITSDSFSDGGRYLAPDAAIAQARKLMAEGADV
                     IDLGPASSNPDAAPVSSDTEIARIAPVLDALKADGIPVSLDSYQPATQAYALSRGVAY
                     LNDIRGFPDAAFYPQLAKSSAKLVVMHSVQDGQADRREAPAGDIMDHIAAFFDARIAA
                     LTGAGIKRNRLVLDPGMGFFLGAAPETSLSVLARFDELRLRFDLPVLLSVSRKSFLRA
                     LTGRGPGDVGAATLAAELAAAAGGADFIRTHEPRPLRDGLAVLAALKETARIR"
     gene            3016..3834
                     /locus_tag="IT892_004730"
                     /note="aph(3'')-Ib"
     CDS             3016..3834
                     /locus_tag="IT892_004730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3'')-Ib"
                     /protein_id="HAP3137811.1"
                     /translation="MKEPPLNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKI
                     APASRRGELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGAD
                     LLKAWPSMGQQLGAVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTP
                     QLDLLARVERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADR
                     YADLALMIANAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
     gene            3834..4670
                     /locus_tag="IT892_004731"
     CDS             3834..4670
                     /locus_tag="IT892_004731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="HAP3137812.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLK
                     PIEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATE
                     IAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMM
                     SNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDP
                     RRIAQMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQT
                     SY"
     gene            complement(4642..5181)
                     /locus_tag="IT892_004732"
     CDS             complement(4642..5181)
                     /locus_tag="IT892_004732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HAP3137813.1"
                     /translation="MPHVAARTASRDRDTGRYQSHRPEQTLLYQIVDEYYPAFAALMA
                     EQGKELPGYVQREFEEFLQCGRLEHGFLRVRCESCHAEHLVAFSCKRRGFCPSCGARR
                     MAESAALLVDEVLPEQPMRQWVLSFPFQLRFLFGVVCGKGRNPTLRLWPAIFSGEIDV
                     FPGDRRSRLISSMTSVAPA"
     gene            complement(5225..5614)
                     /locus_tag="IT892_004733"
     CDS             complement(5225..5614)
                     /locus_tag="IT892_004733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137814.1"
                     /translation="MSTELNSGTVGGFGHMGPNDPYNDGHSGSGSSGGSFNGGGNGGH
                     DNSSGSSYTASFGLITGRHPITVPGTKNINSVDLSAVINNIIHHEGARNNMYLDTANN
                     VRVGVTGTGWQCLATAGISAEGKRTFR"
     gene            5784..>6199
                     /locus_tag="IT892_004734"
     CDS             5784..>6199
                     /locus_tag="IT892_004734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011161230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="HAP3137815.1"
                     /translation="MFCCYNTVHTGDTVTFMAWHTVQETLKLTGKSRSQLYRDMAKGL
                     VSYRTGKNDRREFETSELIRAYGELRTSETPKRHKEGHSKSVVSQAENAQLDVIQQKL
                     DALQQTVTLMLEDKMAREAENRLRNEEREQLQAEISR"
BASE COUNT         1510 a         1642 c         1616 g         1431 t
ORIGIN      
        1 ctggctgacg cgctggcaca ggaaaaaaag cggggattct ggtcgcggct gtttcgctcc
       61 ggttcagagt aacagtgcag gtgactctga tttaccataa catctgttat cagcaccgcc
      121 tgagaggccc tcagggcgtt tctgacggga aaccggtaaa acaggcaaca aaccacccga
      181 aaacccgcca gaaacgcgca ggctctgttt ttacggcatg catgagtatg cgcacaagtg
      241 catagcgcgg aaattcacac cattcagccg gggtaagtcc tgtttccggc gttcttccca
      301 tccgaaaacg gtgaacgggg acgcaattta ttgcgtggcc gtgaagcgtt gccggcgcag
      361 ccggaaaacc cgctgtcagc acgttcagga agggggtgat gtacaaatgg cacagaggat
      421 gaaagtgacg tatgagctga aggaatgatg taaaagtgat gtataagtga tgtaaaagtg
      481 atgtatgaac tgaaggagcg atgtaattct gtagtcagga agaataaccc gttcatgcag
      541 gcatgaacga tacagtgagg aacgcttttt ttgtcacgat ctccccttaa cctgcgtaaa
      601 tcacccgcca tggttgatta tttttcaacc tcaaaatggt catacaccta acgcagccgc
      661 gattttcatc gcaactgcat gaattaaaag aaaaaaaagg aatatttcgt tttcacgagt
      721 aatacccggg tattaaaaat ccactgtaat tacatgaaaa taaagaaata aaaggtaata
      781 ccggagtatt accacgtacg cgggcaagcg aaaaagctat aacgcttccc ggccgacagg
      841 cgacccaaaa tccacagggg catgcaggtt ctcttcagta acctgcgcca ttaaatcaaa
      901 aaggtcatat tcgccgggaa gctgcgtatc agtcgaatcc agttgttcat catattcaga
      961 tggcatgggg tgatatccag tagctgagag gttgttagcg ggtttcgggg cgcagccctg
     1021 aaccagtcat gtagcgctag cggagtgtat actggcttac tatgttgcca cgattgcgaa
     1081 aatcagtgaa gtgcttcatg tggcaggaga aaaaaggcag caccggcgcg tcagcagaat
     1141 atgcgataca ggagatattc cgcttcctcg ctcactgact cgctacgctc ggtcgttcgg
     1201 ctgcggcgag cggtaccggc ttacggacgg ggacggaaat ttcctggaag ataccaggaa
     1261 gacacttagc aaagaagaga taaggccacg gcgaagccgt ttttccatag gctccgcccc
     1321 cctgacaagc atcgcaaaat ctgacgctca aatcagtggt ggcgaaaccc gacaggacta
     1381 taaagatccc aggcgtttcc ccctggtagc tccctcgtgc gctctcctgt tcctgccttt
     1441 cggtttaccg gtgtcattcc gctgttatgg ccgcggtttc tcattccacg cctgacactc
     1501 agttccgtga aggcagttcg ctccaagctg gactgtatgc acgaaccccc cgttcagtcc
     1561 gaccgctgcg ccttgtccgg taactatcaa cttgagtcca acccggaaag acacgacaaa
     1621 acgccactgg cagcagccat tagtaacagg agtgcacgag aagatagatt aagaggtctt
     1681 gaagtagagg cctgactgcg gctacactga aagaacagtt ttggtaatgg cggtctcgtg
     1741 aaccctgtta ccgggttaag cagttcccca actgacttaa ccttcgaaca aaccgcctcc
     1801 ccaggcggtt ttttcgttta cagagcaaga gattacgatt cattgaaaag gatctcaaga
     1861 agatcctttg tagattacta tcaattaatc ttccgaacat gacaccagtc actgttgatt
     1921 acggttaaac cgctccgtaa caggtttccc tcgtattggt gacttgcagc accaaagaag
     1981 caaaaaagat aaatatatct acttattgag agatgatata tttatttcca aaatgctaca
     2041 gatacatcat catgaaacgg atcaccgcaa acaggttact cgcctgggga ttccctttcg
     2101 acccgagcat ccgtatgaga ctcatgctcg attattatta ttatagaagc ccccatgaat
     2161 aaatcgctca tcattttcgg catcgtcaac ataacctcgg acagtttctc cgatggaggc
     2221 cggtatctgg cgccagacgc agccattgcg caggcgcgta agctgatggc cgagggggca
     2281 gatgtgatcg acctcggtcc ggcatccagc aatcccgacg ccgcgcctgt ttcgtccgac
     2341 acagaaatcg cgcgtatcgc gccggtgctg gacgcgctca aggcagatgg cattcccgtc
     2401 tcgctcgaca gttatcaacc cgcgacgcaa gcctatgcct tgtcgcgtgg tgtggcctat
     2461 ctcaatgata ttcgcggttt tccagacgct gcgttctatc cgcaattggc gaaatcatct
     2521 gccaaactcg tcgttatgca ttcggtgcaa gacgggcagg cagatcggcg cgaggcaccc
     2581 gctggcgaca tcatggatca cattgcggcg ttctttgacg cgcgcatcgc ggcgctgacg
     2641 ggtgccggta tcaaacgcaa ccgccttgtc cttgatcccg gcatggggtt ttttctgggg
     2701 gctgctcccg aaacctcgct ctcggtgctg gcgcggttcg atgaattgcg gctgcgcttc
     2761 gatttgccgg tgcttctgtc tgtttcgcgc aaatcctttc tgcgcgcgct cacaggccgt
     2821 ggtccggggg atgtcggggc cgcgacactc gctgcagagc ttgccgccgc cgcaggtgga
     2881 gctgacttca tccgcacaca cgagccgcgc cccttgcgcg acgggctggc ggtattggcg
     2941 gcgctgaaag aaaccgcaag aattcgttaa ctgcacattc gggatatttc tctatattcg
     3001 cgcttcatca gaaaactgaa ggaacctcca ttaaatcgaa ctaatatttt ttttggtgaa
     3061 tcgcattctg actggttgcc tgtcagaggc ggagaatctg gtgattttgt ttttcgacgt
     3121 ggtgacgggc atgccttcgc gaaaatcgca cctgcttccc gccgcggtga gctcgctgga
     3181 gagcgtgacc gcctcatttg gctcaaaggt cgaggtgtgg cttgccccga ggtcatcaac
     3241 tggcaggagg aacaggaggg tgcatgcttg gtgataacgg caattccggg agtaccggcg
     3301 gctgatctgt ctggagcgga tttgctcaaa gcgtggccgt caatggggca gcaacttggc
     3361 gctgttcaca gcctatcggt tgatcaatgt ccgtttgagc gcaggctgtc gcgaatgttc
     3421 ggacgcgccg ttgatgtggt gtcccgcaat gccgtcaatc ccgacttctt accggacgag
     3481 gacaagagta cgccgcagct cgatcttttg gctcgtgtcg aacgagagct accggtgcgg
     3541 ctcgaccaag agcgcaccga tatggttgtt tgccatggtg atccctgcat gccgaacttc
     3601 atggtggacc ctaaaactct tcaatgcacg ggtctgatcg accttgggcg gctcggaaca
     3661 gcagatcgct atgccgattt ggcactcatg attgctaacg ccgaagagaa ctgggcagcg
     3721 ccagatgaag cagagcgcgc cttcgctgtc ctattcaatg tattggggat cgaagccccc
     3781 gaccgcgaac gccttgcctt ctatctgcga ttggaccctc tgacttgggg ttgatgttca
     3841 tgccgcctgt ttttcctgct cattggcacg tttcgcaacc tgttctcatt gcggacacct
     3901 tttccagcct cgtttggaaa gtttcattgc cagacgggac tcctgcaatc gtcaagggat
     3961 tgaaacctat agaagacatt gctgatgaac tgcgcggggc cgactatctg gtatggcgca
     4021 atgggagggg agcagtccgg ttgctcggtc gtgagaacaa tctgatgttg ctcgaatatg
     4081 ccggggagcg aatgctctct cacatcgttg ccgagcacgg cgactaccag gcgaccgaaa
     4141 ttgcagcgga actaatggcg aagctgtatg ccgcatctga ggaacccctg ccttctgccc
     4201 ttctcccgat ccgggatcgc tttgcagctt tgtttcagcg ggcgcgcgat gatcaaaacg
     4261 caggttgtca aactgactac gtccacgcgg cgattatagc cgatcaaatg atgagcaatg
     4321 cctcggaact gcgtgggcta catggcgatc tgcatcatga aaacatcatg ttctccagtc
     4381 gcggctggct ggtgatagat cccgtcggtc tggtcggtga agtgggcttt ggcgccgcca
     4441 atatgttcta cgatccggct gacagagacg acctttgtct cgatcctaga cgcattgcac
     4501 agatggcgga cgcattctct cgtgcgctgg acgtcgatcc gcgtcgcctg ctcgaccagg
     4561 cgtacgctta tgggtgcctt tccgcagctt ggaacgcgga tggagaagag gagcaacgcg
     4621 atctagctat cgcggccgcg atcaagcagg tgcgacagac gtcatactag atatcaagcg
     4681 acttctccta tcccctggga acacatcaat ctcaccggag aatatcgctg gccaaagcct
     4741 tagcgtagga ttccgcccct tcccgcaaac gaccccaaac aggaaacgca gctgaaacgg
     4801 gaagctcaac acccactgac gcatgggttg ttcaggcagt acttcatcaa ccagcaaggc
     4861 ggcactttcg gccatccgcc gcgccccaca gctcgggcag aaaccgcgac gcttacagct
     4921 gaaagcgacc aggtgctcgg cgtggcaaga ctcgcagcga acccgtagaa agccatgctc
     4981 cagccgcccg cattggagaa attcttcaaa ttcccgttgc acatagcccg gcaattcctt
     5041 tccctgctct gccataagcg cagcgaatgc cgggtaatac tcgtcaacga tctgatagag
     5101 aagggtttgc tcgggtcggt ggctctggta acgaccagta tcccgatccc ggctggccgt
     5161 cctggccgcc acatgaggca tgttccgcgt ccttgcaata ctgtgtttac atacagtcta
     5221 tcgcttagcg gaaagttctt ttaccctcag ccgaaatgcc tgccgttgct agacattgcc
     5281 agccagtgcc cgtcactccc actcttacat tgttcgcagt atctaggtac atgttattgc
     5341 gtgcaccttc atgatgtata atgttattaa tgacagcaga aagatcgaca gaattaatat
     5401 tcttcgtacc tgggacagtt atcgggtgtc ggccagtgat gagaccaaag gatgcagtat
     5461 aagatgaacc actactatta tcatggccac cattaccacc accgttaaaa ctacctcccg
     5521 aacttccaga gccgctatga ccatcattgt aggggtcatt tggtcccatg tgaccaaaac
     5581 caccgacagt accgctattt aactctgtac tcataaaatt atcctctttg acttttaaaa
     5641 acagcaaaaa ctgtatttat aacaatgtgt ttatatacag tattcgaaat actacgcccg
     5701 tcaaaaccac accgtcaaca ggttttttgt gtatttttca cgcctcacgg gcagcctcag
     5761 accttttgtg ttaaaacagt aatatgttct gctgttacaa tacggtacac acaggagaca
     5821 ctgtcacttt tatggcatgg cacacagttc aagagacact gaaattaaca ggaaagtcgc
     5881 gctcgcaatt atatcgtgac atggctaaag gccttgtcag ctatcgcaca ggaaaaaatg
     5941 atcgccggga gttcgagacc agtgaactga ttcgggccta tggcgagctg cgcacttctg
     6001 agacaccaaa aaggcacaag gagggacact ccaaatctgt cgttagccag gcggaaaatg
     6061 ctcagctaga cgtcattcag cagaaactgg acgctctgca gcagactgtt accctaatgc
     6121 ttgaagacaa gatggcgcgg gaagcagaaa accgcctgcg aaatgaggag agggaacaac
     6181 tacaggccga aattagccg
//
LOCUS       DACAOP010000333         2963 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.215, whole genome shotgun sequence.
ACCESSION   DACAOP010000333 DACAOP010000000
VERSION     DACAOP010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2963
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.215"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            76..936
                     /locus_tag="IT892_004735"
     CDS             76..936
                     /locus_tag="IT892_004735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(3)-IId"
                     /protein_id="HAP3137816.1"
                     /translation="MHTRKAITEALQKLGVQTGDLLMVHASLKAIGPVEGGAETVVAA
                     LRSAVGPTGTVMGYASWDRSPYEETLNGARLDDEARRTWLPFDPATAGTYRGFGLLNQ
                     FLVQAPGARRSAHPDASMVAVGPLAETLTEPHELGHALGEGSPVERFVRLGGKALLLG
                     APLNSVTALHYAEAVADIPNKRWVTYEMPMLGRDGEVAWKTASDYDSNGILDCFAIEG
                     KPDAVETIANAYVKLGRHREGVVGFAQCYLFDAQDIVTFGVTYLEKHFGTTPIVPPHE
                     AVERSCEPSG"
     gene            949..1491
                     /locus_tag="IT892_004736"
     CDS             949..1491
                     /locus_tag="IT892_004736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP3137817.1"
                     /translation="MIIWINGPFGAGKTTLAKRLRDRRSKSLIFDPEEIGFVVKETVP
                     MPASGDYQDLPLWRGLTIAAVREIRRNYSQDIIIPMTLVHPDYLTEILDGVRRIDDQL
                     LHIFLTLNEDLLRHRIANQTMHPDPNRNAEIREWRLANVARCLAARERLPCTTRVLDS
                     GAHTSDELAAMVLDGIDGRT"
     gene            complement(1973..2164)
                     /locus_tag="IT892_004737"
     CDS             complement(1973..2164)
                     /locus_tag="IT892_004737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000951934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137818.1"
                     /translation="MAIALMGAGFSATDTSDAVNILYPITMTVQANKAWQASGLKKSF
                     FLPSHKKVRGGEKISYARL"
     gene            2188..2415
                     /locus_tag="IT892_004738"
     CDS             2188..2415
                     /locus_tag="IT892_004738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137819.1"
                     /translation="MVNSYSLSDDSGVMAAAAITHFLFGQAVFSYLNGWSVLIGPGTG
                     LDSTGCKYARDLMGLVAFTAFIVTFLFRGYS"
     gene            2466..>2963
                     /locus_tag="IT892_004739"
     CDS             2466..>2963
                     /locus_tag="IT892_004739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137820.1"
                     /translation="MSQLSQLRSPAAVQAAIDEFVQLGRTKFLARHGYGKSRDFLVRD
                     PKTGTDCDSKAIAGVAFGKQFPEQGPLTADSFSGGEATVVPALTRLGFRIIRIGEDWS
                     EEEVLATVEDYFDMLRAEAAGEPYNKSEHNQALRQLLNGRSKSSVELKHQNISAVLDA
                     LGLPYI"
BASE COUNT          597 a          840 c          872 g          654 t
ORIGIN      
        1 acttaatgat ttttaccaaa atcattaggg gattcatcag cgtatagtgt tttgcagttt
       61 agaggagata tcgcgatgca tacgcggaag gcaataacgg aggcgcttca aaaactcgga
      121 gtccaaaccg gtgacctctt gatggtgcat gcctcactta aagcgattgg tccggtcgaa
      181 ggaggagcgg agacggtcgt tgccgcgtta cgctccgcgg ttgggccgac tggcactgtg
      241 atgggatacg cgtcgtggga ccgatcaccc tacgaggaga ctctgaatgg cgctcggctg
      301 gatgacgaag cccgccgtac ctggctgccg ttcgatcccg caacagccgg gacttaccgt
      361 gggttcggcc tgctgaatca atttctggtt caagcccccg gcgcgcggcg cagcgcgcac
      421 cccgatgcat cgatggtcgc ggttggtccg ctggctgaaa cgctgacgga gcctcacgaa
      481 ctcggtcacg ccttggggga aggatcgccc gtcgagcggt tcgttcgcct tggcgggaag
      541 gccctgctgt tgggtgcgcc gctaaactcc gttaccgcat tgcactacgc cgaggcggtt
      601 gccgatatcc ccaacaaacg gtgggtgacg tatgagatgc cgatgcttgg aagagacggt
      661 gaagtcgcct ggaaaacggc atcggattac gattcaaacg gcattctcga ttgctttgct
      721 atcgaaggaa agccggatgc ggttgaaact atagcaaatg cttacgtgaa gctcggtcgc
      781 catcgagaag gtgtcgtggg ctttgctcag tgctacctgt tcgacgcgca ggacatcgtg
      841 acgttcggcg tcacctatct tgagaagcat ttcggaacca ctccgatcgt gcctccgcac
      901 gaggccgtcg agcgctcttg cgagccttca ggttagaggc cgtcgacaat gataatctgg
      961 atcaacggac ctttcggcgc cggaaagacg acgctcgcta agcggctgcg cgatcggcgt
     1021 tccaaatcgc tgatctttga ccccgaggaa atcgggttcg tggtgaaaga aacggtcccc
     1081 atgccagcga gcggagacta tcaggatctc cccttgtgga ggggacttac gatcgcggcg
     1141 gtcagggaga ttcgaaggaa ttactcgcag gacatcatca tcccaatgac gctcgtgcac
     1201 ccggactatc tgactgagat actcgacggg gtaaggcgga tcgacgatca gctgctgcac
     1261 atctttctga cgctcaacga ggacctattg cgtcaccgga tcgcgaacca gaccatgcat
     1321 cctgacccga atcgaaatgc ggagattcga gagtggcgat tagcgaatgt cgcccgatgc
     1381 ttggccgcaa gggaacggct tccatgcaca acccgtgttc tcgatagtgg tgcacacacc
     1441 agcgatgaac tcgcagcgat ggtgctcgac ggaatcgatg ggcgcacctg atcgccttcg
     1501 acgcctgcgc aaagcgtagc gcgagggtgg cgggctcacg accaaacgcc cagaggtcga
     1561 tcatcgcagg gatgtttggc tttgtggtgc ggacgacggg actcgaaccc gtactctcac
     1621 agagaagcag attttcgtac cacctcgact ttcgccgccg tctgatgacg ttcgtggtct
     1681 ggactgtccc ttcgccattg cccgaaggct ttaggcgccg cccgtccagt ctctacacct
     1741 tcccccgaag gggcttggct cgggattggc ttagggtatt gcccgttagc gttccccgac
     1801 tttgagcggt tctactccgc ggatttcccc gcgggcactc caattttaaa gtctgctgcg
     1861 tctaccgatt tcgccacgtc cgcctttttt cgccgttcct agcgctcgtg cgatgcacct
     1921 atgttgcacc tagcgccgaa tcgttcttcg tcatcctgaa aaaccacgtc tcctaaagcc
     1981 ttgcatagct tatcttttct ccaccacgaa cttttttgtg ggatggtaga aaaaaagact
     2041 ttttaagtcc gctggcttgc caggccttgt tagcttgtac ggtcatggtt atcgggtaaa
     2101 gaatattgac ggcatcgctg gtgtcggtgg ctgaaaagcc ggctcccatc agggcaatag
     2161 ccatttcaga tgcaggcgta cagggcaatg gtcaacagct acagcctgtc tgacgattcc
     2221 ggcgtcatgg ctgcggcggc tatcacgcat tttttgttcg gtcaggcggt gttttcgtac
     2281 ctcaatggtt ggagcgtgtt gatcggacct ggtacaggtt tggacagcac gggctgcaaa
     2341 tacgcaaggg atttaatggg cctggtggcg ttcacggctt ttatcgtgac gtttctgttc
     2401 aggggctact cataatctcg tggctcggcg gttcccggca caccatgaca gtaaggaagg
     2461 accctgtgtc tcaactctcc cagcttcgaa gccccgccgc cgtgcaggct gccatcgatg
     2521 agttcgtgca actgggccgc acgaaattcc tggcgcgcca cggctacggc aagtcccgcg
     2581 acttcctggt acgtgatccg aagaccggca ccgattgcga ttccaaggcc atcgccggtg
     2641 tggccttcgg caagcaattt cccgagcagg gcccgctcac tgctgacagc ttctccggtg
     2701 gcgaggcgac cgtcgttccg gcgctgacgc ggctcgggtt tcgcatcatt cgcatcggcg
     2761 aagactggtc cgaagaagag gtcctggcca cggtcgaaga ctatttcgac atgctgcgtg
     2821 ccgaggcggc tggggagccg tacaacaagt ccgagcacaa ccaggcactg cgccaactgc
     2881 tgaacggtcg cagcaagtct tcagtcgagc tcaagcacca gaacattagc gccgtactcg
     2941 atgccctggg cctgccctat atc
//
LOCUS       DACAOP010000334         2261 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.229, whole genome shotgun sequence.
ACCESSION   DACAOP010000334 DACAOP010000000
VERSION     DACAOP010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.229"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            61..615
                     /locus_tag="IT892_004740"
     CDS             61..615
                     /locus_tag="IT892_004740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ib3"
                     /protein_id="HAP3137821.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLA
                     DVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGWWEEETDPGVRGIDQL
                     LANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTV
                     TTPDGPAVYMVQTRQAFERTRSDA"
     gene            882..2141
                     /gene="cmlA"
                     /locus_tag="IT892_004741"
                     /pseudo
     CDS             882..2141
                     /gene="cmlA"
                     /locus_tag="IT892_004741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001256773.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CmlA family chloramphenicol efflux MFS
                     transporter"
BASE COUNT          471 a          579 c          656 g          555 t
ORIGIN      
        1 gatgttacgc agcagggcag tcgccctaaa acaaagttag gcatcacaaa gtacagcatc
       61 gtgaccaaca gcaacgattc cgtcacactg cgcctcatga ctgagcatga ccttgcgatg
      121 ctctatgagt ggctaaatcg atctcatatc gtcgagtggt ggggcggaga agaagcacgc
      181 ccgacacttg ctgacgtaca ggaacagtac ttgccaagcg ttttagcgca agagtccgtc
      241 actccataca ttgcaatgct gaatggagag ccgattgggt atgcccagtc gtacgttgct
      301 cttggaagcg gggacggatg gtgggaagaa gaaaccgatc caggagtacg cggaatagac
      361 cagttactgg cgaatgcatc acaactgggc aaaggcttgg gaaccaagct ggttcgagct
      421 ctggttgagt tgctgttcaa tgatcccgag gtcaccaaga tccaaacgga cccgtcgccg
      481 agcaacttgc gagcgatccg atgctacgag aaagcggggt ttgagaggca aggtaccgta
      541 accaccccag atggtccagc cgtgtacatg gttcaaacac gccaggcatt cgagcgaaca
      601 cgcagtgatg cctaaccctt ccatcgaggg ggacgtccaa gggctggcgc ccttggccgc
      661 ccctcatgtc aaacgttggg cgcacaataa ggctcctcgc agagttgctt gaaagttgtt
      721 acgattcaaa ttcaatcatg agatagtcgg cagatgagca tttccaagaa cgcagacaag
      781 taagccgcag caaccttcat ttttcggttg ttgcggcgtt ctcaagaatc cttttgctct
      841 acgggagcgc cgccaaatcc tttgttcaag gagatggttt cgtgcgctca aaaaatttta
      901 gttggcggta ctcccttgcc gccacggtgt tgttgttatc accgttcgat ttattggcat
      961 cactcggcat ggacatgtac ttgccggcag tgccgtttat gccaaacgcg cttggtacga
     1021 cagcgagcac aattcagctt acgctgacaa cgtacttggt catgattggt gccggtcagc
     1081 tcttgtttgg accgctatcg gaccgactgg ggcgccgccc cgttctactg ggaggtggcc
     1141 tcgcctaggt tgtggcgtca atgggcctcg ctcttacgtc atcggctgaa gtctttctgg
     1201 ggcttcggat tcttcaggct tgtggtgcct cggcgtgcct tgtttccacg tttgcaacag
     1261 tacgtgacat ttacgcaggt cgcgaggaaa gtaatgtcat ttacggcata ctcggatcca
     1321 tgctggccat ggtcccggcg gtaggcccat tgctcggagc gctcgtcgac atgtggcttg
     1381 ggtggcgggc tatctttgcg tttctaggtt tgggcatgat cgctgcatct gcagcagcgt
     1441 ggcgattctg gcctgaaacc cgggtgcaac gagttgcggg cttgcaatgg tcgcagctgc
     1501 tactccccgt taagtgcctg aacttctggt tgtacacgtt gtgttacgcc gctggaatgg
     1561 gtagcttctt cgtctttttc tccattgcgc ccggactaat gatgggcagg caaggtgtgt
     1621 ctcagcttgg cttcagcctg ctgttcgcca cagtggcaat tgccatggtg tttacagctc
     1681 gttttatggg gcgtgtaata cccaagtggg gcagcccaag cgtcttgcga atgggaatgg
     1741 gatgcctgat agctggagca gtattgcttg ccatcaccga aatatgggct tcgcagtccg
     1801 tgttaggctt tatttctcca atgtggctag tgggtattgg tgtcgccaca gcggtatctg
     1861 tggcgcccaa tggcgctctt cgaggattcg accatgttgc tggaacggtc acggcagtct
     1921 acttctgctt gggcggtgta ctgctaggaa gcatcggaac gttgatcatt tcgctgttgc
     1981 cgcgcaacac ggcttggccg gttgtcgtgt actgtttgac ccttgcaaca gtcgtgctcg
     2041 gtctgtcttg tgtttcccga gcggagggct ctcgcggcca gggggagcat gatgtggtcg
     2101 cgctacaaag tgcggaaagt acgtcaaatc ccaatcgttg agagaatgtg gcaagctatc
     2161 gcccaacaaa tcgctgcagc cgacccaaaa ccgctacgcg gtttcggtcg gctgagctca
     2221 ggcgttagat gcactaagca cataattgct cacagccaaa c
//
LOCUS       DACAOP010000335         2109 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.233, whole genome shotgun sequence.
ACCESSION   DACAOP010000335 DACAOP010000000
VERSION     DACAOP010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2109
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.233"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            complement(<1..416)
                     /gene="tetR(B)"
                     /locus_tag="IT892_004742"
     CDS             complement(<1..416)
                     /gene="tetR(B)"
                     /locus_tag="IT892_004742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HAP3137822.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVG"
     gene            498..1703
                     /gene="tet(B)"
                     /locus_tag="IT892_004743"
     CDS             498..1703
                     /gene="tet(B)"
                     /locus_tag="IT892_004743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HAP3137823.1"
                     /translation="MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
     gene            complement(1816..>2109)
                     /locus_tag="IT892_004744"
     CDS             complement(1816..>2109)
                     /locus_tag="IT892_004744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP3137824.1"
                     /translation="IDNNKNLIPIQEVMPIIGWNELEKISLEYITGKVNAIVSKLIQE
                     NQLKAYDDDVLKNLLNGWFMHIAIHAKNLKELADKKGQFIAIYRGFLLSLKDK"
BASE COUNT          534 a          404 c          450 g          721 t
ORIGIN      
        1 tgccccacag cgctgagtgc atataatgca ttctctagtg aaaaaccttg ttggcataaa
       61 aaggctaatt gattttcgag agtttcatac tgtttttctg taggccgtgt acctaaatgt
      121 acttttgctc catcgcgatg acttagtaaa gcacatctaa aacttttagc gttattacgt
      181 aaaaaatctt gccagctttc cccttctaaa gggcaaaagt gagtatggtg cctatctaac
      241 atctcaatgg ctaaggcgtc gagcaaagcc cgcttatttt ttacatgcca atacaatgta
      301 ggctgctcta cacctagctt ctgggcgagt ttacgggttg ttaaaccttc gattccgacc
      361 tcattaagca gctctaatgc gctgttaatc actttacttt tatctaatct agacatcatt
      421 aattcctaat ttttgttgac actctatcat tgatagagtt attttaccac tccctatcag
      481 tgatagagaa aagtgaaatg aatagttcga caaagatcgc attggtaatt acgttactcg
      541 atgccatggg gattggcctt atcatgccag tcttgccaac gttattacgt gaatttattg
      601 cttcggaaga tatcgctaac cactttggcg tattgcttgc actttatgcg ttaatgcagg
      661 ttatctttgc tccttggctt ggaaaaatgt ctgaccgatt tggtcggcgc ccagtgctgt
      721 tgttgtcatt aataggcgca tcgctggatt acttattgct ggctttttca agtgcgcttt
      781 ggatgctgta tttaggccgt ttgctttcag ggatcacagg agctactggg gctgtcgcgg
      841 catcggtcat tgccgatacc acctcagctt ctcaacgcgt gaagtggttc ggttggttag
      901 gggcaagttt tgggcttggt ttaatagcgg ggcctattat tggtggtttt gcaggagaga
      961 tttcaccgca tagtcccttt tttatcgctg cgttgctaaa tattgtcgct ttccttgtgg
     1021 ttatgttttg gttccgtgaa accaaaaata cacgtgataa tacagatacc gaagtagggg
     1081 ttgagacgca atcgaattcg gtatacatca ctttatttaa aacgatgccc attttgttga
     1141 ttatttattt ttcagcgcaa ttgataggcc aaattcccgc aacggtgtgg gtgctattta
     1201 ccgaaaatcg ttttggatgg aatagcatga tggttggctt ttcattagcg ggtcttggtc
     1261 ttttacactc agtattccaa gcctttgtgg caggaagaat agccactaaa tggggcgaaa
     1321 aaacggcagt actgctcgga tttattgcag atagtagtgc atttgccttt ttagcgttta
     1381 tatctgaagg ttggttagtt ttccctgttt taattttatt ggctggtggt gggatcgctt
     1441 tacctgcatt acagggagtg atgtctatcc aaacaaagag tcatcagcaa ggtgctttac
     1501 agggattatt ggtgagcctt accaatgcaa ccggtgttat tggcccatta ctgtttgctg
     1561 ttatttataa tcattcacta ccaatttggg atggctggat ttggattatt ggtttagcgt
     1621 tttactgtat tattatcctg ctatcgatga ccttcatgtt aacccctcaa gctcagggga
     1681 gtaaacagga gacaagtgct tagttatttc gtcaccaaat gatgttattc cgcgaaatat
     1741 aatgaccctc ttgataaccc aagagggcat tttttacgat aaagaagatt tagcttcaaa
     1801 taaaacctat ctattttatt tatctttcaa gctcaataaa aagccgcggt aaatagcaat
     1861 aaattggcct tttttatcgg caagctcttt taggtttttc gcatgtattg cgatatgcat
     1921 aaaccagcca ttgagtaagt ttttaagcac atcatcatca taagctttaa gttggttctc
     1981 ttggatcaat ttgctgacaa tggcgtttac cttaccagta atgtattcaa ggctaatttt
     2041 ttcaagttca ttccaaccaa tgataggcat cacttcttgg atagggataa ggtttttatt
     2101 attatcaat
//
LOCUS       DACAOP010000336         1783 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.246, whole genome shotgun sequence.
ACCESSION   DACAOP010000336 DACAOP010000000
VERSION     DACAOP010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1783
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.246"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            207..1019
                     /locus_tag="IT892_004745"
     CDS             207..1019
                     /locus_tag="IT892_004745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase NDM-5"
                     /protein_id="HAP3137825.1"
                     /translation="MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQ
                     RFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLLVDTAWTDDQTAQIL
                     NWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHS
                     LTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSL
                     GNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR"
     gene            1023..1388
                     /gene="ble"
                     /locus_tag="IT892_004746"
     CDS             1023..1388
                     /gene="ble"
                     /locus_tag="IT892_004746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bleomycin binding protein Ble-MBL"
                     /protein_id="HAP3137826.1"
                     /translation="MADHVTPNLPSRDFDVTEAFYAKLGFATSWKDRGWMILQRGGLQ
                     LEFFPYPDLDPATSSFGCCLRLDDLDAMVALVNAAGAEEKSTGWPRFKAPQLEASGLR
                     IGYLIDPDCTLVRLIQNPD"
     gene            1393..>1783
                     /locus_tag="IT892_004747"
     CDS             1393..>1783
                     /locus_tag="IT892_004747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-(5'-phosphoribosyl)anthranilate isomerase"
                     /protein_id="HAP3137827.1"
                     /translation="MPAKIKICGISTPEALDATIAARADYAGLVFYPASPRAVTSNVA
                     GALTSRAAGQIAMVGLFVDADDAVIADALVAAKLNALQLHGSESPERVAQLRARFGKP
                     VWKALPVASASDVARAAAYAGAADLILF"
BASE COUNT          344 a          531 c          536 g          372 t
ORIGIN      
        1 acaaacatga tctcatatca gggacttgtt cgcaccttcc ttagagaaat ttgctcagct
       61 tgttgattat catatggctt ttgaaactgt cgcacctcat gtttgaattc gccccatatt
      121 tttgctacag tgaaccaaat taagatcatc tatttactag gcctcgcatt tgcggggttt
      181 ttaatgctga ataaaaggaa aacttgatgg aattgcccaa tattatgcac ccggtcgcga
      241 agctgagcac cgcattagcc gctgcattga tgctgagcgg gtgcatgccc ggtgaaatcc
      301 gcccgacgat tggccagcaa atggaaactg gcgaccaacg gtttggcgat ctggttttcc
      361 gccagctcgc accgaatgtc tggcagcaca cttcctatct cgacatgccg ggtttcgggg
      421 cagtcgcttc caacggtttg atcgtcaggg atggcggccg cgtgctgttg gtcgataccg
      481 cctggaccga tgaccagacc gcccagatcc tcaactggat caagcaggag atcaacctgc
      541 cggtcgcgct ggcggtggtg actcacgcgc atcaggacaa gatgggcggt atggacgcgc
      601 tgcatgcggc ggggattgcg acttatgcca atgcgttgtc gaaccagctt gccccgcaag
      661 aggggctggt tgcggcgcaa cacagcctga ctttcgccgc caatggctgg gtcgaaccag
      721 caaccgcgcc caactttggc ccgctcaagg tattttaccc cggccccggc cacaccagtg
      781 acaatatcac cgttgggatc gacggcaccg acatcgcttt tggtggctgc ctgatcaagg
      841 acagcaaggc caagtcgctc ggcaatctcg gtgatgccga cactgagcac tacgccgcgt
      901 cagcgcgcgc gtttggtgcg gcgttcccca aggccagcat gatcgtgatg agccattccg
      961 cccccgatag ccgcgccgca atcactcata cggcccgcat ggccgacaag ctgcgctgag
     1021 ccatggctga ccacgtcacc cccaatctgc catcgcgcga tttcgatgtg acagaggcgt
     1081 tttatgcgaa gctgggcttt gcgacgagtt ggaaggatcg cggctggatg atcctgcagc
     1141 gcggcggttt gcagctcgaa ttcttcccct atcctgacct cgacccagct acgagctcgt
     1201 tcggctgttg cctgcggttg gatgatctcg atgccatggt ggcattggtg aacgcggcgg
     1261 gagccgagga aaaaagcacc ggctggccgc gcttcaaagc tccgcaactg gaggcgagcg
     1321 gcctgaggat cggctacctg atcgatcccg actgcacgct ggtgcggctg atccagaacc
     1381 ccgactgacc gcatgcccgc gaaaatcaag atttgcggga tcagcacacc cgaggcgctc
     1441 gatgcgacca tcgcggcgcg ggcggactat gccgggttgg tgttctatcc agcgtcgccc
     1501 cgtgcggtta cgtcgaatgt cgcgggcgct ttgacatcgc gcgcagctgg ccagatcgcc
     1561 atggtcggtt tgttcgtcga tgcggatgat gctgtcatcg ccgacgcact ggtggcagcc
     1621 aagctgaacg cgctgcagct gcacggttcg gaatcgcccg aacgcgtggc ccagttgcgc
     1681 gcgcggtttg gcaagccggt gtggaaggcg ctgcccgtcg ccagcgccag cgatgtcgca
     1741 cgcgccgcag cctatgccgg ggcggcggac ttgatcttgt tcg
//
LOCUS       DACAOP010000337         1757 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.247, whole genome shotgun sequence.
ACCESSION   DACAOP010000337 DACAOP010000000
VERSION     DACAOP010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1757
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.247"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            112..459
                     /locus_tag="IT892_004748"
     CDS             112..459
                     /locus_tag="IT892_004748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="HAP3137828.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     gene            453..1292
                     /gene="sul1"
                     /locus_tag="IT892_004749"
     CDS             453..1292
                     /gene="sul1"
                     /locus_tag="IT892_004749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /protein_id="HAP3137829.1"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     gene            1420..>1757
                     /locus_tag="IT892_004750"
     CDS             1420..>1757
                     /locus_tag="IT892_004750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004194535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP3137830.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARI
                     DRTFAETFVLRSELLVASCSDGIVGCCTLSAEDPEFWPDALKGEAAYLHKLAVRRTHA
                     GRGVSSALIEA"
BASE COUNT          327 a          513 c          527 g          390 t
ORIGIN      
        1 gcgttagatg cactaagcac ataattgctc acagccaaac tatcaggtca agtctgcttt
       61 tattattttt aagcgtgcat aataagccct acacaaattg ggagatatat catgaaaggc
      121 tggctttttc ttgttatcgc aatagttggc gaagtaatcg caacatccgc attaaaatct
      181 agcgagggct ttactaagct tgccccttcc gccgttgtca taatcggtta tggcatcgca
      241 ttttattttc tttctctggt tctgaaatcc atccctgtcg gtgttgctta tgcagtctgg
      301 tcgggactcg gcgtcgtcat aattacagcc attgcctggt tgcttcatgg gcaaaagctt
      361 gatgcgtggg gctttgtagg tatggggctc ataattgctg cctttttgct cgcccgatcc
      421 ccatcgtgga agtcgctgcg gaggccgacg ccatggtgac ggtgttcggc attctgaatc
      481 tcaccgagga ctccttcttc gatgagagcc ggcggctaga ccccgccggc gctgtcaccg
      541 cggcgatcga aatgctgcga gtcggatcag acgtcgtgga tgtcggaccg gccgccagcc
      601 atccggacgc gaggcctgta tcgccggccg atgagatcag acgtattgcg ccgctcttag
      661 acgccctgtc cgatcagatg caccgtgttt caatcgacag cttccaaccg gaaacccagc
      721 gctatgcgct caagcgcggc gtgggctacc tgaacgatat ccaaggattt cctgaccctg
      781 cgctctatcc cgatattgct gaggcggact gcaggctggt ggttatgcac tcagcgcagc
      841 gggatggcat cgccacccgc accggtcacc ttcgacccga agacgcgctc gacgagattg
      901 tgcggttctt cgaggcgcgg gtttccgcct tgcgacggag cggggtcgct gccgaccggc
      961 tcatcctcga tccggggatg ggatttttct tgagccccgc accggaaaca tcgctgcacg
     1021 tgctgtcgaa ccttcaaaag ctgaagtcgg cgttggggct tccgctattg gtctcggtgt
     1081 cgcggaaatc cttcttgggc gccaccgttg gccttcctgt aaaggatctg ggtccagcga
     1141 gccttgcggc ggaacttcac gcgatcggca atggcgctga ctacgtccgc acccacgcgc
     1201 ctggagatct gcgaagcgca atcaccttct cggaaaccct cgcgaaattt cgcagtcgcg
     1261 acgccagaga ccgagggtta gatcatgcct agcattcacc ttccggccgc ccgctagcgg
     1321 accctggtca ggttccgcga aggtgggcgc agacatgctg ggctcgtcag gatcaaactg
     1381 cactatgagg cggcggttca taccgcgcca ggggagcgaa tggacagcga ggagcctccg
     1441 aacgttcggg tcgcctgctc gggtgatatc gacgaggttg tgcggctgat gcacgacgct
     1501 gcggcgtgga tgtccgccaa gggaacgccc gcctgggacg tcgcgcggat cgaccggaca
     1561 ttcgcggaga ccttcgtcct gagatccgag ctcctagtcg cgagttgcag cgacggcatc
     1621 gtcggctgtt gcaccttgtc ggccgaggat cccgagttct ggcccgacgc cctcaagggg
     1681 gaggccgcat atctgcacaa gctcgcggtg cgacggacac atgcgggccg gggtgtcagc
     1741 tccgcgctga tcgaggc
//
LOCUS       DACAOP010000338         1498 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.253, whole genome shotgun sequence.
ACCESSION   DACAOP010000338 DACAOP010000000
VERSION     DACAOP010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1498
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.253"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            <1..328
                     /locus_tag="IT892_004751"
     CDS             <1..328
                     /locus_tag="IT892_004751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137831.1"
                     /translation="DKFITTDYLQQCPENYIKEAKYDMAVGHLLLKSFWANEAVFQMM
                     MLSYNLFLLFKFDSLDSSEYRQQIKTFRLKYVFLAAKIIKTARYVIMKLSENYPYKGV
                     YEKCLV"
     gene            complement(476..598)
                     /locus_tag="IT892_004752"
     CDS             complement(476..598)
                     /locus_tag="IT892_004752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP3137832.1"
                     /translation="MHSLCHHLKLPIRSIRVTSVFPKFHVCFLLASKITISRRI"
     gene            578..1453
                     /locus_tag="IT892_004753"
     CDS             578..1453
                     /locus_tag="IT892_004753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A extended-spectrum beta-lactamase
                     CTX-M-14"
                     /protein_id="HAP3137833.1"
                     /translation="MVTKRVQRMMFAAAACIPLLLGSAPLYAQTSAVQQKLAALEKSS
                     GGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKP
                     ADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGD
                     ETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRAQLVTWLKGNT
                     TGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESR
                     RDVLASAARIIAEGL"
BASE COUNT          403 a          331 c          416 g          348 t
ORIGIN      
        1 tgataagttt atcaccaccg actatttgca acagtgccct gaaaactata tcaaagaagc
       61 caaatacgac atggcggtgg gtcatctctt gctaaagtca ttttgggcga atgaagccgt
      121 gtttcaaatg atgatgcttt catataacct atttttgttg ttcaagtttg attccttgga
      181 ctcttcagaa tacagacagc aaataaagac ctttcgtttg aagtatgtat ttcttgcagc
      241 aaaaataatc aaaaccgcaa gatatgtaat catgaagttg tcggaaaact atccgtacaa
      301 gggagtgtat gaaaaatgtc tggtataata agaatatcat caataaaatt gagtgttgct
      361 ctgtggataa cttgcagagt ttattaagta tcattgcagc aaagatgaaa tcaatgattt
      421 atcaaaaatg attgaaaggt ggttgtaaat aatgttacaa tgtgtgagaa gcagtctaaa
      481 ttcttcgtga aatagtgatt tttgaagcta ataaaaaaca cacgtggaat ttagggaata
      541 ctgatgtaac acggattgac cgtattggga gtttgagatg gtgacaaaga gagtgcaacg
      601 gatgatgttc gcggcggcgg cgtgcattcc gctgctgctg ggcagcgcgc cgctttatgc
      661 gcagacgagt gcggtgcagc aaaagctggc ggcgctggag aaaagcagcg gagggcggct
      721 gggcgtcgcg ctcatcgata ccgcagataa tacgcaggtg ctttatcgcg gtgatgaacg
      781 ctttccaatg tgcagtacca gtaaagttat ggcggccgcg gcggtgctta agcagagtga
      841 aacgcaaaag cagctgctta atcagcctgt cgagatcaag cctgccgatc tggttaacta
      901 caatccgatt gccgaaaaac acgtcaacgg cacaatgacg ctggcagaac tgagcgcggc
      961 cgcgttgcag tacagcgaca ataccgccat gaacaaattg attgcccagc tcggtggccc
     1021 gggaggcgtg acggcttttg cccgcgcgat cggcgatgag acgtttcgtc tggatcgcac
     1081 tgaacctacg ctgaataccg ccattcccgg cgacccgaga gacaccacca cgccgcgggc
     1141 gatggcgcag acgttgcgtc agcttacgct gggtcatgcg ctgggcgaaa cccagcgggc
     1201 gcagttggtg acgtggctca aaggcaatac gaccggcgca gccagcattc gggccggctt
     1261 accgacgtcg tggactgtgg gtgataagac cggcagcggc gactacggca ccaccaatga
     1321 tattgcggtg atctggccgc agggtcgtgc gccgctggtt ctggtgacct attttaccca
     1381 gccgcaacag aacgcagaga gccgccgcga tgtgctggct tcagcggcga gaatcatcgc
     1441 cgaagggctg taactggttt tgttgaataa atcgaacttt tgctgagttg aaggatca
//
LOCUS       DACAOP010000339         1313 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.263, whole genome shotgun sequence.
ACCESSION   DACAOP010000339 DACAOP010000000
VERSION     DACAOP010000339.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.263"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            10..1143
                     /gene="blaEC"
                     /locus_tag="IT892_004754"
     CDS             10..1143
                     /gene="blaEC"
                     /locus_tag="IT892_004754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HAP3137834.1"
                     /translation="MFKTTLCALLITASCSTFAAPQKINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPATKYWSELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWG
                     YREGKAVHVSPGALDAETYGVKSTIEDMACWVRSNMNPRDINDKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDSIINGSGNKIALAARPVKAITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVTAAWQILNALQ"
BASE COUNT          344 a          348 c          318 g          303 t
ORIGIN      
        1 ccagacccta tgttcaaaac gacgctctgc gccttattaa ttaccgcctc ttgctccaca
       61 tttgctgccc cccaaaaaat caacgatatt gtgcatcgca caattacccc gcttatagag
      121 caacaaaaga tccccggtat ggcggtggcg gtaatttatc agggtaaacc ttattacttt
      181 acctggggct atgcggacat cgccaaaaaa cagcccgtca cacagcaaac gttgtttgag
      241 ttaggttcgg tcagcaaaac atttacgggc gtgcttggtg gcgacgctat tgctcgaggg
      301 gaaatcaagt taagcgatcc cgcaacaaaa tactggtctg aacttaccgc taaacagtgg
      361 aacgggatca cactattaca tctcgcaacc tacaccgctg gcggcctgcc attgcaggtg
      421 ccggatgagg tgaaatcctc aagcgacttg ctgcgcttct atcaaaactg gcagcctgca
      481 tgggctccag gaacacaacg tctgtatgcc aactccagta tcggtttgtt cggcgcactg
      541 gctgtgaagc cgtctggttt gagttttgag caggcgatgc aaacacgtgt cttccagcca
      601 ctcaaactca accatacgtg gattaatgta ccgcccgcag aagaaaagaa ttacgcctgg
      661 ggatatcgcg aaggcaaggc agttcatgtt tcgccagggg cgttagatgc tgaaacttat
      721 ggtgtgaagt cgaccattga agatatggcc tgctgggtac gaagcaatat gaatccccgt
      781 gatatcaacg acaaaacact tcagcaaggg atacaactgg cacaatctcg ctactggcaa
      841 accggcgata tgtatcaggg cctgggctgg gaaatgctgg actggccggt aaatcctgac
      901 agcatcatta acggcagtgg caataaaatt gcactggcag cacgccccgt aaaagcgatt
      961 acgcccccaa ctcctgcagt acgcgcatca tgggtacata aaacaggggc aaccggcgga
     1021 tttggtagct atgtcgcgtt tattccagaa aaagagctgg gtatagtgat gctggctaac
     1081 aaaaactatc ccaatccagc gagagtcacc gccgcctggc agattctcaa cgctctacag
     1141 taaaatttca tcgggtccga attttcggac cttttctgcg cttttccttg ctgtcatcta
     1201 cacttagaaa aaaaccagta aggaaacatt tatgcgcctg ctccctctcg ttgccgcagc
     1261 gacagctgca tttctggtcg ttgcctgcag ttctcctacg ccgccgcgtg gcg
//
LOCUS       DACAOP010000340         1226 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.268, whole genome shotgun sequence.
ACCESSION   DACAOP010000340 DACAOP010000000
VERSION     DACAOP010000340.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1226
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.268"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            109..204
                     /locus_tag="IT892_004755"
     CDS             109..204
                     /locus_tag="IT892_004755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAP3137835.1"
                     /translation="MLVFQMRYQMRYVDKTSTVLKQTKKSDYADK"
     gene            330..1067
                     /gene="erm(B)"
                     /locus_tag="IT892_004756"
     CDS             330..1067
                     /gene="erm(B)"
                     /locus_tag="IT892_004756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP3137836.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPRVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          462 a          199 c          197 g          368 t
ORIGIN      
        1 gataagttta tcaccaccga ctatttgcaa cagtgccaaa ttttgtataa taggaattga
       61 agttaaatta gatgctaaaa atttgtaatt aagaaggagg gattcgtcat gttggtattc
      121 caaatgcgtt atcaaatgcg ttatgtagat aaaacatcta ctgttttgaa acagactaaa
      181 aaaagtgatt acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta
      241 tgacttttta aacagataac taaaattaca aacaaatcgt ttaacttctg tatttgttta
      301 tagatgtaat cacttcagga gtaaattaca tgaacaaaaa tataaaatat tctcaaaact
      361 ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca attgaattta aaagaaaccg
      421 ataccgttta cgaaattgga acaggtaaag ggcatttaac gacgaaactg gctaaaataa
      481 gtaaacaggt aacgtctatt gaattagaca gtcatctatt caacttatcg tcagaaaaat
      541 taaaactgaa tactcgtgtc actttaattc accaagatat tctacagttt caattcccta
      601 acaaacagag gtataaaatt gttgggaata ttccttacca tttaagcaca caaattatta
      661 aaaaagtggt ttttgaaagc catgcgtctg acatctatct gattgttgaa gaaggattct
      721 acaagcgtac cttggatatt caccgaacac tagggttgct cttgcacact caagtctcga
      781 ttcagcaatt gcttaagctg ccagcggaat gctttcatcc taaaccaaga gtaaacagtg
      841 tcttaataaa acttacccgc cataccacag atgttccaga taaatattgg aagctatata
      901 cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca actgtttact aaaaatcagt
      961 ttcatcaagc aatgaaacac gccaaagtaa acaatttaag taccgttact tatgagcaag
     1021 tattgtctat ttttaatagt tatctattat ttaacgggag gaaataattc tatgagtcgc
     1081 ttttgtaaat ttggaaagtt acacgttact aaagggaatg tagataaatt attaggtata
     1141 ctactgacag cttccaagga gctaaagagg tccctagact agcaagaagt acacaagaag
     1201 ccttaaagat tatagaaaag cttttc
//
LOCUS       DACAOP010000341         1052 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.276, whole genome shotgun sequence.
ACCESSION   DACAOP010000341 DACAOP010000000
VERSION     DACAOP010000341.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1052
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.276"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            107..1012
                     /gene="mph(A)"
                     /locus_tag="IT892_004757"
     CDS             107..1012
                     /gene="mph(A)"
                     /locus_tag="IT892_004757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HAP3137837.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAQLAAAE"
BASE COUNT          186 a          338 c          334 g          194 t
ORIGIN      
        1 caaaaggctg cctcatcgct aactttgcaa cagtgccgga ttgaatataa ccgacgtgac
       61 tgttacattt aggtggctaa acccgtcaag ccctcaggag tgaatcatga ccgtagtcac
      121 gaccgccgat acctcccaac tgtacgcact tgcagcccga catgggctca agctccatgg
      181 cccgctgact gtcaatgagc ttgggctcga ctataggatc gtgatcgcca ccgtcgacga
      241 tggacgtcgg tgggtgctgc gcatcccgcg ccgagccgag gtaagcgcga aggtcgaacc
      301 agaggcgcgg gtgctggcaa tgctcaagaa tcgcctgccg ttcgcggtgc cggactggcg
      361 cgtggccaac gccgagctcg ttgcctatcc catgctcgaa gactcgactg cgatggtcat
      421 ccagcctggt tcgtccacgc ccgactgggt cgtgccgcag gactcggagg tcttcgcgga
      481 gagcttcgcg accgcgctcg ccgccctgca tgccgtcccc atttccgccg ccgtggatgc
      541 ggggatgctc atccgtacac cgacgcaggc ccgtcagaag gtggccgacg acgttgaccg
      601 cgtccgacgc gagttcgtgg tgaacgacaa gcgcctccac cggtggcagc gctggctcga
      661 cgacgattcg tcgtggccag atttctccgt ggtggtgcat ggcgatctct acgtgggcca
      721 tgtgctcatc gacaacacgg agcgcgtcag cgggatgatc gactggagcg aggcccgcgt
      781 tgatgaccct gccatcgaca tggccgcgca ccttatggtc tttggtgaag aggggctcgc
      841 gaagctcctc ctcacgtatg aagcggccgg tggccgggtg tggccgcggc tcgcccacca
      901 catcgcggag cgccttgcgt tcggggcggt cacctacgca ctcttcgccc tcgactcggg
      961 taacgaagag tacctcgctg cggcgaaggc gcagctcgcc gcagcggaat gagcgaacgt
     1021 cgatatagcc cgctcgcgac gctgttcgcg gc
//
LOCUS       DACAOP010000342          998 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.280, whole genome shotgun sequence.
ACCESSION   DACAOP010000342 DACAOP010000000
VERSION     DACAOP010000342.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..998
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.280"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            76..864
                     /locus_tag="IT892_004758"
     CDS             76..864
                     /locus_tag="IT892_004758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /protein_id="HAP3137838.1"
                     /translation="MGEFFPAQVFKQLSHARAVIERHLAATLDTIHLFGSAIDGGLKP
                     DSDIDLLVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWRYP
                     ARRELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSAATFFEPVPKE
                     HFSKALFDTIAQWNAESDWKGDERNVVLALARIWYSASTGLIAPKDVAAAWVSERLPA
                     EHRPLICKARAAYLGSEDDDLAMRVEETAAFVRYAKATIERILR"
BASE COUNT          206 a          286 c          287 g          219 t
ORIGIN      
        1 ttgtggtttt gctgcgcaaa agtattccac aaagccgcaa cttaaaagct gccgctgaac
       61 ttaacgttag gcatcatggg tgaatttttc cctgcacaag ttttcaagca gctgtcccac
      121 gctcgcgcgg tgatcgagcg ccatctggct gcgacactgg acacaatcca cctgttcgga
      181 tctgcgatcg atggagggct gaagccggac agcgacatag acttgctcgt gaccgtcagc
      241 gccgcaccta acgattcgct ccggcaggcg ctaatgctcg atttgctgaa agtctcatca
      301 ccgccaggcg atggcggaac atggcgaccg ctggagctaa ctgttgtcgc tcgaagcgaa
      361 gtagtgcctt ggcgctatcc ggcgcggcgt gagcttcagt tcggtgagtg gctccgccac
      421 gacatccttt ccggaacgtt cgagcctgcc gttctggatc acgatcttgc gattttgctg
      481 accaaggcga ggcaacacag ccttgcgctt ctaggcccat ccgcagccac gtttttcgag
      541 ccggtgccga aggagcattt ctccaaggcg cttttcgaca ctattgccca gtggaatgca
      601 gagtcggatt ggaagggtga cgagcggaac gtcgttcttg ctcttgctcg catttggtac
      661 agcgcttcaa ctggtctcat tgctcctaag gacgttgctg ccgcatgggt atcggagcgt
      721 ttgcctgccg agcatcggcc cctcatctgc aaggcacgcg cggcgtacct gggtagcgag
      781 gacgacgacc tagcaatgcg cgtcgaagag acggccgcgt tcgttcgata tgccaaagca
      841 acgattgaga gaatcttgcg ttgagcggca tgtgcgaaaa gtgcatcgac ccgcgccgag
      901 ggcatctgat gcctaactcg gcgttcaagc ggacgggctg cgcccgccgc tcaactatgc
      961 gttagatgca ctaagcacat aattgctcac agccaaac
//
LOCUS       DACAOP010000343          779 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.292, whole genome shotgun sequence.
ACCESSION   DACAOP010000343 DACAOP010000000
VERSION     DACAOP010000343.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..779
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.292"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            31..489
                     /gene="gpt"
                     /locus_tag="IT892_004759"
     CDS             31..489
                     /gene="gpt"
                     /locus_tag="IT892_004759"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAP3137839.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            581..>779
                     /locus_tag="IT892_004760"
     CDS             581..>779
                     /locus_tag="IT892_004760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP3137840.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREI"
BASE COUNT          182 a          206 c          200 g          191 t
ORIGIN      
        1 gccgtagata aacaggctgg gacacttcac atgagcgaaa aatacatcgt cacctgggac
       61 atgttgcaga tccatgcacg taaactcgca agccgactga tgccttctga acaatggaaa
      121 ggcattattg ccgtaagccg tggcggtctg gtaccgggtg cgttactggc gcgtgaactg
      181 ggtattcgtc atgtcgatac cgtttgtatt tccagctacg atcacgacaa ccagcgcgag
      241 cttaaagtgc tgaaacgcgc agaaggcgat ggcgaaggct tcatcgttat tgatgacctg
      301 gtggataccg gtggtactgc ggttgcgatt cgtgaaatgt atccaaaagc gcactttgtc
      361 accatcttcg caaaaccggc tggtcgtccg ctggttgatg actatgttgt tgatatcccg
      421 caagatacct ggattgaaca gccgtgggat atgggcgtcg tattcgtccc gccaatctcc
      481 ggtcgctaat cttttcaacg cctggcactg ccgggcgttg ttctttttaa cttcaggcgg
      541 gttacaatag tttccagtaa gtattctgga ggctgcatcc atgacacagg caaacctgag
      601 cgaaaccctg ttcaaacccc gctttaaaca tcctgaaacc tcgacgctag tccgccgctt
      661 taatcacggc gcacaaccgc ctgtgcagtc ggcccttgat ggtaaaacca tccctcactg
      721 gtatcgcatg attaaccgtc tgatgtggat ctggcgcggc attgacccac gcgaaatcc
//
LOCUS       DACAOP010000344          582 bp    DNA     linear   BCT 09-NOV-2020
DEFINITION  TPA_asm: Escherichia coli strain hkcpe106
            SAMN15904775-rid10982953.guided.301, whole genome shotgun sequence.
ACCESSION   DACAOP010000344 DACAOP010000000
VERSION     DACAOP010000344.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15904775
            Sequence Read Archive: SRR12517574
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-NOV-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-NOV-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000881491.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000881491.1
            Genome Coverage       :: 30x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/07/2020 03:26:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 4,759
            CDSs (total)                      :: 4,695
            Genes (coding)                    :: 4,583
            CDSs (with protein)               :: 4,583
            Genes (RNA)                       :: 64
            rRNAs                             :: 2, 4 (16S, 23S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 112
            CDSs (without protein)            :: 112
            Pseudo Genes (ambiguous residues) :: 0 of 112
            Pseudo Genes (frameshifted)       :: 51 of 112
            Pseudo Genes (incomplete)         :: 53 of 112
            Pseudo Genes (internal stop)      :: 26 of 112
            Pseudo Genes (multiple problems)  :: 16 of 112
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..582
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15904775-rid10982953.guided.301"
                     /strain="hkcpe106"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="Hong Kong"
                     /lat_lon="22.3797 N 114.2017 E"
                     /collection_date="2015-10-07"
                     /collected_by="CUHK"
     gene            58..531
                     /locus_tag="IT892_004761"
     CDS             58..531
                     /locus_tag="IT892_004761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA17"
                     /protein_id="HAP3137841.1"
                     /translation="MKISLISAVSENGVIGSGPDIPWSVKGEQLLFKALTYNQWLLVG
                     RKTFDSMGVLPNRKYAVVSKNGISSSNENVLVFPSIENALKELSKVTDHVYVSGGGQI
                     YNSLIEKADIIHLSTVHVEVEGDIKFPIMPENFNLVFEQFFMSNINYTYQIWKKG"
BASE COUNT          186 a          104 c          117 g          175 t
ORIGIN      
        1 gatgttacgc agcagggcag tcgccctaaa acaaagttag ccattaaggg agttaaattg
       61 aaaatatcat tgatttctgc agtgtcagaa aatggcgtaa tcggtagtgg tcctgatatc
      121 ccgtggtcag taaaaggtga gcaactactc tttaaagcgc tcacatataa tcaatggctc
      181 cttgtcggaa gaaaaacatt tgactctatg ggtgttcttc caaatcgcaa atatgcagta
      241 gtgtcaaaga acggaatttc aagctcaaat gaaaacgtcc tagtttttcc ttcaatagaa
      301 aatgctttga aagagctatc aaaagttaca gatcatgtat atgtctctgg cgggggtcaa
      361 atctataata gccttattga aaaagcagat ataattcatt tgtctactgt tcacgttgaa
      421 gtcgaaggtg atatcaaatt ccctataatg cctgagaatt tcaatttggt ttttgaacag
      481 ttttttatgt ctaatataaa ttatacatac cagatttgga aaaaaggcta acaatgcgtt
      541 gcagcaccag tcgcttcgct ccttggacag cttttaagtc gc
//
